id category name description xref provided_by synonym iri knowledge_source object predicate relation same_as subject subsets CHEBI:26547 biolink:ChemicalSubstance rhamnoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_26547 CHEBI:26548 biolink:ChemicalSubstance rhamnosylglucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_26548 CHEBI:26543 biolink:ChemicalSubstance rhamnogalacturonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_26543 CHEBI:26544 biolink:ChemicalSubstance rhamnonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26544 CHEBI:26545 biolink:ChemicalSubstance rhamnonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26545 CHEBI:26546 biolink:ChemicalSubstance rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_26546 CHEBI:51507 biolink:ChemicalSubstance benzil go-plus.json http://purl.obolibrary.org/obo/CHEBI_51507 chebi_ph7_3 CHEBI:51509 biolink:ChemicalSubstance (R)-benzoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_51509 chebi_ph7_3 CHEBI:26558 biolink:ChemicalSubstance ribonucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26558 CHEBI:26554 biolink:ChemicalSubstance ribitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26554 CHEBI:26556 biolink:ChemicalSubstance 1-ribosylimidazolecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26556 GO:0099593 biolink:BiologicalProcess endocytosed synaptic vesicle to endosome fusion Fusion of an endocytosed synaptic vesicle with an endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0099593 CHEBI:26523 biolink:ChemicalSubstance reactive oxygen species go-plus.json http://purl.obolibrary.org/obo/CHEBI_26523 GO:0099592 biolink:BiologicalProcess endocytosed synaptic vesicle processing via endosome The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. go-plus.json synaptic vesicle processing via endosome involved in synaptic vesicle recycling http://purl.obolibrary.org/obo/GO_0099592 GO:0099590 biolink:BiologicalProcess neurotransmitter receptor internalization A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0099590 CHEBI:26536 biolink:ChemicalSubstance retinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26536 CHEBI:75504 biolink:ChemicalSubstance pyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_75504 chebi_ph7_3 CHEBI:26537 biolink:ChemicalSubstance retinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26537 CHEBI:75507 biolink:ChemicalSubstance 3-dehydropyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_75507 chebi_ph7_3 CHEBI:26533 biolink:ChemicalSubstance reticuline go-plus.json http://purl.obolibrary.org/obo/CHEBI_26533 CHEBI:26534 biolink:ChemicalSubstance retinals go-plus.json http://purl.obolibrary.org/obo/CHEBI_26534 CHEBI:26507 biolink:ChemicalSubstance dihydroxyquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_26507 CHEBI:26508 biolink:ChemicalSubstance quinoline N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26508 CHEBI:26509 biolink:ChemicalSubstance quinoline alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26509 CHEBI:75525 biolink:ChemicalSubstance D-galactopyranuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75525 chebi_ph7_3 CHEBI:26515 biolink:ChemicalSubstance quinolizidine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26515 CHEBI:26516 biolink:ChemicalSubstance quinolizidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26516 CHEBI:75524 biolink:ChemicalSubstance 2,3-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75524 chebi_ph7_3 CHEBI:75529 biolink:ChemicalSubstance 1-lauroyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75529 chebi_ph7_3 CHEBI:26512 biolink:ChemicalSubstance quinolinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26512 CHEBI:26513 biolink:ChemicalSubstance quinolines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26513 CHEBI:75528 biolink:ChemicalSubstance 3-lauroyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75528 chebi_ph7_3 CHEBI:26519 biolink:ChemicalSubstance radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_26519 CHEBI:75522 biolink:ChemicalSubstance beta-L-galactose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75522 chebi_ph7_3 CHEBI:75536 biolink:ChemicalSubstance 1-myristoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75536 chebi_ph7_3 CHEBI:75537 biolink:ChemicalSubstance 3-myristoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75537 chebi_ph7_3 CHEBI:75539 biolink:ChemicalSubstance 1-monolauroylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75539 chebi_ph7_3 NCBITaxon:289376 biolink:OrganismalEntity Thermodesulfovibrio yellowstonii DSM 11347 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_289376 CHEBI:75533 biolink:ChemicalSubstance 3-lauroyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75533 chebi_ph7_3 CHEBI:75547 biolink:ChemicalSubstance 1-monodecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75547 chebi_ph7_3 CHEBI:75545 biolink:ChemicalSubstance 2-keto-3-deoxy-L-galactonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75545 chebi_ph7_3 CHEBI:75546 biolink:ChemicalSubstance 2-oleoyl-3-palmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75546 chebi_ph7_3 CHEBI:75540 biolink:ChemicalSubstance 2-oleoyl-3-myristoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75540 chebi_ph7_3 CHEBI:75542 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75542 chebi_ph7_3 GO:0051599 biolink:BiologicalProcess response to hydrostatic pressure Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. go-plus.json response to biomechanical stress|response to static fluid pressure http://purl.obolibrary.org/obo/GO_0051599 GO:0002621 biolink:BiologicalProcess positive regulation of non-professional antigen presenting cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. go-plus.json up regulation of non-professional antigen presenting cell antigen processing and presentation|upregulation of non-professional antigen presenting cell antigen processing and presentation|stimulation of non-professional antigen presenting cell antigen processing and presentation|up-regulation of non-professional antigen presenting cell antigen processing and presentation|activation of non-professional antigen presenting cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002621 GO:0099533 biolink:BiologicalProcess positive regulation of presynaptic cytosolic calcium concentration Any process that increases the concentration of calcium ions in the presynaptic cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0099533 goslim_synapse GO:0099534 biolink:MolecularActivity calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations. go-plus.json presynaptic calcium ion buffering|regulation of presynaptic cytosolic calcium ion concentration by calcium ion buffering|calcium ion binding involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099534 goslim_synapse GO:0002622 biolink:BiologicalProcess regulation of B cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation. go-plus.json regulation of B-cell antigen processing and presentation|regulation of B-lymphocyte antigen processing and presentation|regulation of B lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002622 GO:0002623 biolink:BiologicalProcess negative regulation of B cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation. go-plus.json negative regulation of B-cell antigen processing and presentation|negative regulation of B-lymphocyte antigen processing and presentation|down-regulation of B cell antigen processing and presentation|negative regulation of B lymphocyte antigen processing and presentation|downregulation of B cell antigen processing and presentation|down regulation of B cell antigen processing and presentation|inhibition of B cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002623 GO:0099531 biolink:BiologicalProcess presynaptic process involved in chemical synaptic transmission The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0099531 goslim_synapse|gocheck_do_not_annotate GO:0051597 biolink:BiologicalProcess response to methylmercury Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus. go-plus.json response to MeHg+|response to CH3-Hg+ http://purl.obolibrary.org/obo/GO_0051597 GO:0051598 biolink:BiologicalProcess meiotic recombination checkpoint signaling A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes. go-plus.json pachytene checkpoint|meiotic recombination checkpoint|signal transduction involved in meiotic recombination checkpoint http://purl.obolibrary.org/obo/GO_0051598 GO:0002624 biolink:BiologicalProcess positive regulation of B cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation. go-plus.json upregulation of B cell antigen processing and presentation|positive regulation of B-cell antigen processing and presentation|stimulation of B cell antigen processing and presentation|up-regulation of B cell antigen processing and presentation|activation of B cell antigen processing and presentation|positive regulation of B-lymphocyte antigen processing and presentation|up regulation of B cell antigen processing and presentation|positive regulation of B lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002624 GO:0099532 biolink:BiologicalProcess synaptic vesicle endosomal processing The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. go-plus.json synaptic vesicle processing via endosome http://purl.obolibrary.org/obo/GO_0099532 goslim_synapse NCBITaxon:4896 biolink:OrganismalEntity Schizosaccharomyces pombe go-plus.json fission yeast|Schizosaccharomyces malidevorans http://purl.obolibrary.org/obo/NCBITaxon_4896 GO:0099530 biolink:MolecularActivity G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane. go-plus.json G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0099530 goslim_synapse NCBITaxon:4894 biolink:OrganismalEntity Schizosaccharomycetaceae go-plus.json fission yeasts|Schizosaccharomycetoideae http://purl.obolibrary.org/obo/NCBITaxon_4894 GO:0002620 biolink:BiologicalProcess negative regulation of non-professional antigen presenting cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. go-plus.json downregulation of non-professional antigen presenting cell antigen processing and presentation|down regulation of non-professional antigen presenting cell antigen processing and presentation|inhibition of non-professional antigen presenting cell antigen processing and presentation|down-regulation of non-professional antigen presenting cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002620 NCBITaxon:4895 biolink:OrganismalEntity Schizosaccharomyces go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4895 GO:0002629 biolink:BiologicalProcess negative regulation of proteolysis associated with antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. go-plus.json down regulation of proteolysis associated with antigen processing and presentation|downregulation of proteolysis associated with antigen processing and presentation|down-regulation of proteolysis associated with antigen processing and presentation|inhibition of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002629 GO:0051591 biolink:BiologicalProcess response to cAMP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus. go-plus.json response to 3',5'-cAMP|response to adenosine 3',5'-cyclophosphate|response to cyclic AMP|response to 3',5' cAMP http://purl.obolibrary.org/obo/GO_0051591 GO:0051592 biolink:BiologicalProcess response to calcium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. go-plus.json response to Ca2+ ion http://purl.obolibrary.org/obo/GO_0051592 GO:0099539 biolink:BiologicalProcess neuropeptide secretion from presynapse The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration. go-plus.json neuropeptide secretion from presynapse via dense core granule exocytosis http://purl.obolibrary.org/obo/GO_0099539 goslim_synapse GO:0051590 biolink:BiologicalProcess positive regulation of neurotransmitter transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of neurotransmitter transport|upregulation of neurotransmitter transport|stimulation of neurotransmitter transport|up-regulation of neurotransmitter transport|activation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051590 CHEBI:51586 biolink:ChemicalSubstance benzoins go-plus.json http://purl.obolibrary.org/obo/CHEBI_51586 GO:0002625 biolink:BiologicalProcess regulation of T cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation. go-plus.json regulation of T-cell antigen processing and presentation|regulation of T-lymphocyte antigen processing and presentation|regulation of T lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002625 GO:0051595 biolink:BiologicalProcess response to methylglyoxal Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. go-plus.json response to pyruvaldehyde http://purl.obolibrary.org/obo/GO_0051595 GO:0099537 biolink:BiologicalProcess trans-synaptic signaling Cell-cell signaling in either direction across the synaptic cleft. go-plus.json http://purl.obolibrary.org/obo/GO_0099537 goslim_synapse GO:0051596 biolink:BiologicalProcess methylglyoxal catabolic process The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. MetaCyc:METHGLYUT-PWY|MetaCyc:Methylglyoxal-Detoxification go-plus.json methylglyoxal degradation|methylglyoxal breakdown|methylglyoxal catabolism http://purl.obolibrary.org/obo/GO_0051596 GO:0099538 biolink:BiologicalProcess synaptic signaling via neuropeptide Cell-cell signaling to or from a synapse, mediated by a peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0099538 goslim_synapse GO:0002626 biolink:BiologicalProcess negative regulation of T cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation. go-plus.json down-regulation of T cell antigen processing and presentation|negative regulation of T lymphocyte antigen processing and presentation|downregulation of T cell antigen processing and presentation|down regulation of T cell antigen processing and presentation|inhibition of T cell antigen processing and presentation|negative regulation of T-cell antigen processing and presentation|negative regulation of T-lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002626 GO:0051593 biolink:BiologicalProcess response to folic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus. go-plus.json cellular response to folate|cellular response to vitamin B9 http://purl.obolibrary.org/obo/GO_0051593 GO:0002627 biolink:BiologicalProcess positive regulation of T cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation. go-plus.json positive regulation of T-lymphocyte antigen processing and presentation|up regulation of T cell antigen processing and presentation|positive regulation of T lymphocyte antigen processing and presentation|upregulation of T cell antigen processing and presentation|stimulation of T cell antigen processing and presentation|positive regulation of T-cell antigen processing and presentation|activation of T cell antigen processing and presentation|up-regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002627 GO:0099535 biolink:CellularComponent synapse-associated extracellular matrix The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft. go-plus.json extra-synaptic extracellular matrix http://purl.obolibrary.org/obo/GO_0099535 goslim_synapse GO:0099536 biolink:BiologicalProcess synaptic signaling Cell-cell signaling to, from or within a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099536 goslim_synapse GO:0002628 biolink:BiologicalProcess regulation of proteolysis associated with antigen processing and presentation Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002628 GO:0051594 biolink:BiologicalProcess detection of glucose The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal. go-plus.json glucose sensing|glucose detection|glucose perception http://purl.obolibrary.org/obo/GO_0051594 GO:0099544 biolink:CellularComponent perisynaptic space The extracellular region immediately adjacent to to a synapse. go-plus.json extrasynaptic space http://purl.obolibrary.org/obo/GO_0099544 goslim_synapse GO:0002632 biolink:BiologicalProcess negative regulation of granuloma formation Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation. go-plus.json down regulation of granuloma formation|downregulation of granuloma formation|down-regulation of granuloma formation|inhibition of granuloma formation http://purl.obolibrary.org/obo/GO_0002632 GO:0099545 biolink:BiologicalProcess trans-synaptic signaling by trans-synaptic complex Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0099545 goslim_synapse GO:0002633 biolink:BiologicalProcess positive regulation of granuloma formation Any process that activates or increases the frequency, rate, or extent of granuloma formation. go-plus.json upregulation of granuloma formation|up regulation of granuloma formation|activation of granuloma formation|stimulation of granuloma formation|up-regulation of granuloma formation http://purl.obolibrary.org/obo/GO_0002633 GO:0002634 biolink:BiologicalProcess regulation of germinal center formation Any process that modulates the frequency, rate, or extent of germinal center formation. go-plus.json http://purl.obolibrary.org/obo/GO_0002634 GO:0099542 biolink:BiologicalProcess trans-synaptic signaling by endocannabinoid Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0099542 goslim_synapse GO:0002635 biolink:BiologicalProcess negative regulation of germinal center formation Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. go-plus.json inhibition of germinal center formation|down regulation of germinal center formation|downregulation of germinal center formation|down-regulation of germinal center formation http://purl.obolibrary.org/obo/GO_0002635 GO:0099543 biolink:BiologicalProcess trans-synaptic signaling by soluble gas Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft. go-plus.json http://purl.obolibrary.org/obo/GO_0099543 goslim_synapse GO:0099540 biolink:BiologicalProcess trans-synaptic signaling by neuropeptide Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. go-plus.json http://purl.obolibrary.org/obo/GO_0099540 goslim_synapse GO:0099541 biolink:BiologicalProcess trans-synaptic signaling by lipid Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0099541 goslim_synapse GO:0002630 biolink:BiologicalProcess positive regulation of proteolysis associated with antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. go-plus.json up-regulation of proteolysis associated with antigen processing and presentation|upregulation of proteolysis associated with antigen processing and presentation|up regulation of proteolysis associated with antigen processing and presentation|activation of proteolysis associated with antigen processing and presentation|stimulation of proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002630 GO:0002631 biolink:BiologicalProcess regulation of granuloma formation Any process that modulates the frequency, rate, or extent of granuloma formation. go-plus.json http://purl.obolibrary.org/obo/GO_0002631 GO:0099548 biolink:BiologicalProcess trans-synaptic signaling by nitric oxide Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide. go-plus.json http://purl.obolibrary.org/obo/GO_0099548 goslim_synapse GO:0002636 biolink:BiologicalProcess positive regulation of germinal center formation Any process that activates or increases the frequency, rate, or extent of germinal center formation. go-plus.json up-regulation of germinal center formation|upregulation of germinal center formation|up regulation of germinal center formation|activation of germinal center formation|stimulation of germinal center formation http://purl.obolibrary.org/obo/GO_0002636 GO:0099549 biolink:BiologicalProcess trans-synaptic signaling by carbon monoxide Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide. go-plus.json http://purl.obolibrary.org/obo/GO_0099549 goslim_synapse GO:0002637 biolink:BiologicalProcess regulation of immunoglobulin production Any process that modulates the frequency, rate, or extent of immunoglobulin production. go-plus.json regulation of immunoglobulin secretion|regulation of antibody production|regulation of immunoglobulin biosynthetic process http://purl.obolibrary.org/obo/GO_0002637 GO:0002638 biolink:BiologicalProcess negative regulation of immunoglobulin production Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. go-plus.json negative regulation of immunoglobulin secretion|down-regulation of immunoglobulin production|inhibition of immunoglobulin production|negative regulation of immunoglobulin biosynthetic process|down regulation of immunoglobulin production|downregulation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002638 GO:0099546 biolink:BiologicalProcess protein catabolic process, modulating synaptic transmission Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0099546 goslim_synapse CHEBI:51570 biolink:ChemicalSubstance biotins go-plus.json http://purl.obolibrary.org/obo/CHEBI_51570 GO:0099547 biolink:BiologicalProcess regulation of translation at synapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099547 goslim_synapse GO:0002639 biolink:BiologicalProcess positive regulation of immunoglobulin production Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. go-plus.json stimulation of immunoglobulin production|positive regulation of immunoglobulin secretion|positive regulation of immunoglobulin biosynthetic process|up-regulation of immunoglobulin production|upregulation of immunoglobulin production|up regulation of immunoglobulin production|activation of immunoglobulin production http://purl.obolibrary.org/obo/GO_0002639 CHEBI:51571 biolink:ChemicalSubstance diphenylethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_51571 CHEBI:51569 biolink:ChemicalSubstance N-acyl-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51569 GO:0099511 biolink:MolecularActivity voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel. go-plus.json http://purl.obolibrary.org/obo/GO_0099511 goslim_synapse GO:0002600 biolink:BiologicalProcess positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. go-plus.json upregulation of antigen processing and presentation of lipid antigen via MHC class Ib|up regulation of antigen processing and presentation of lipid antigen via MHC class Ib|activation of antigen processing and presentation of lipid antigen via MHC class Ib|positive regulation of lipid antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation of lipid antigen via MHC class Ib|up-regulation of antigen processing and presentation of lipid antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002600 GO:0099512 biolink:CellularComponent supramolecular fiber A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. go-plus.json fibril http://purl.obolibrary.org/obo/GO_0099512 GO:0002601 biolink:BiologicalProcess regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. go-plus.json regulation of polysaccharide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002601 GO:0002602 biolink:BiologicalProcess negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. go-plus.json down-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|negative regulation of polysaccharide antigen processing and presentation via MHC class II|downregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|down regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002602 GO:0099510 biolink:MolecularActivity calcium ion binding involved in regulation of cytosolic calcium ion concentration The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations. go-plus.json regulation of cytosolic calcium ion concentration by calcium ion buffering http://purl.obolibrary.org/obo/GO_0099510 GO:0002607 biolink:BiologicalProcess regulation of myeloid dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002607 GO:0099519 biolink:BiologicalProcess dense core granule cytoskeletal transport The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments. go-plus.json dense core granule cytoskeletal transport|dense core vesicle cytoskeletal trafficking http://purl.obolibrary.org/obo/GO_0099519 GO:0002608 biolink:BiologicalProcess negative regulation of myeloid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. go-plus.json down-regulation of myeloid dendritic cell antigen processing and presentation|downregulation of myeloid dendritic cell antigen processing and presentation|down regulation of myeloid dendritic cell antigen processing and presentation|inhibition of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002608 GO:0002609 biolink:BiologicalProcess positive regulation of myeloid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. go-plus.json stimulation of myeloid dendritic cell antigen processing and presentation|up-regulation of myeloid dendritic cell antigen processing and presentation|activation of myeloid dendritic cell antigen processing and presentation|up regulation of myeloid dendritic cell antigen processing and presentation|upregulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002609 GO:0099517 biolink:BiologicalProcess synaptic vesicle transport along microtubule The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors. go-plus.json http://purl.obolibrary.org/obo/GO_0099517 goslim_synapse GO:0099518 biolink:BiologicalProcess vesicle cytoskeletal trafficking The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. go-plus.json cytoskeletal fiber-based vesicle localization|vesicle cytoskeletal transport http://purl.obolibrary.org/obo/GO_0099518 GO:0002603 biolink:BiologicalProcess positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. go-plus.json positive regulation of polysaccharide antigen processing and presentation via MHC class II|up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|activation of antigen processing and presentation of polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002603 GO:0099515 biolink:BiologicalProcess actin filament-based transport The transport of organelles or other particles from one location in the cell to another along actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0099515 GO:0002604 biolink:BiologicalProcess regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002604 GO:0099516 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099516 GO:0002605 biolink:BiologicalProcess negative regulation of dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation. go-plus.json down regulation of dendritic cell antigen processing and presentation|inhibition of dendritic cell antigen processing and presentation|down-regulation of dendritic cell antigen processing and presentation|downregulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002605 GO:0099513 biolink:CellularComponent polymeric cytoskeletal fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0099513 GO:0002606 biolink:BiologicalProcess positive regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation. go-plus.json upregulation of dendritic cell antigen processing and presentation|stimulation of dendritic cell antigen processing and presentation|up-regulation of dendritic cell antigen processing and presentation|activation of dendritic cell antigen processing and presentation|up regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002606 GO:0099514 biolink:BiologicalProcess synaptic vesicle cytoskeletal transport The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors. go-plus.json http://purl.obolibrary.org/obo/GO_0099514 goslim_synapse GO:0002610 biolink:BiologicalProcess regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002610 GO:0099522 biolink:CellularComponent cytosolic region Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol. go-plus.json region of cytosol http://purl.obolibrary.org/obo/GO_0099522 gocheck_do_not_annotate GO:0002611 biolink:BiologicalProcess negative regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. go-plus.json downregulation of plasmacytoid dendritic cell antigen processing and presentation|down-regulation of plasmacytoid dendritic cell antigen processing and presentation|inhibition of plasmacytoid dendritic cell antigen processing and presentation|down regulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002611 GO:0099523 biolink:CellularComponent presynaptic cytosol The region of the cytosol consisting of all cytosol that is part of the presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099523 goslim_synapse GO:0099520 biolink:MolecularActivity ion antiporter activity involved in regulation of presynaptic membrane potential Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. go-plus.json ion antiporter activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099520 goslim_synapse GO:0002612 biolink:BiologicalProcess positive regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. go-plus.json up regulation of plasmacytoid dendritic cell antigen processing and presentation|activation of plasmacytoid dendritic cell antigen processing and presentation|stimulation of plasmacytoid dendritic cell antigen processing and presentation|up-regulation of plasmacytoid dendritic cell antigen processing and presentation|upregulation of plasmacytoid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002612 GO:0099521 biolink:MolecularActivity ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. go-plus.json ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099521 goslim_synapse GO:0002613 biolink:BiologicalProcess regulation of monocyte antigen processing and presentation Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002613 GO:0002618 biolink:BiologicalProcess positive regulation of macrophage antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation. go-plus.json stimulation of macrophage antigen processing and presentation|up-regulation of macrophage antigen processing and presentation|activation of macrophage antigen processing and presentation|up regulation of macrophage antigen processing and presentation|upregulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002618 NCBITaxon:4892 biolink:OrganismalEntity Saccharomycetales go-plus.json budding yeasts|Endomycetales http://purl.obolibrary.org/obo/NCBITaxon_4892 GO:0002619 biolink:BiologicalProcess regulation of non-professional antigen presenting cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002619 NCBITaxon:4893 biolink:OrganismalEntity Saccharomycetaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4893 NCBITaxon:4890 biolink:OrganismalEntity Ascomycota go-plus.json ascomycetes|sac fungi|ascomycetes http://purl.obolibrary.org/obo/NCBITaxon_4890 GO:0099528 biolink:MolecularActivity G protein-coupled neurotransmitter receptor activity Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein coupled neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0099528 GO:0099529 biolink:MolecularActivity neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel). go-plus.json http://purl.obolibrary.org/obo/GO_0099529 goslim_synapse NCBITaxon:4891 biolink:OrganismalEntity Saccharomycetes go-plus.json Hemiascomycetes http://purl.obolibrary.org/obo/NCBITaxon_4891 GO:0099526 biolink:BiologicalProcess presynapse to nucleus signaling pathway A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications). go-plus.json presynaptic signaling to nucleus http://purl.obolibrary.org/obo/GO_0099526 goslim_synapse GO:0002614 biolink:BiologicalProcess negative regulation of monocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation. go-plus.json downregulation of monocyte antigen processing and presentation|down regulation of monocyte antigen processing and presentation|inhibition of monocyte antigen processing and presentation|down-regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002614 GO:0002615 biolink:BiologicalProcess positive regulation of monocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation. go-plus.json up regulation of monocyte antigen processing and presentation|upregulation of monocyte antigen processing and presentation|stimulation of monocyte antigen processing and presentation|up-regulation of monocyte antigen processing and presentation|activation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002615 GO:0099527 biolink:BiologicalProcess postsynapse to nucleus signaling pathway A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications). go-plus.json postsynaptic signaling to nucleus http://purl.obolibrary.org/obo/GO_0099527 goslim_synapse GO:0099524 biolink:CellularComponent postsynaptic cytosol The region of the cytosol consisting of all cytosol that is part of the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099524 goslim_synapse GO:0002616 biolink:BiologicalProcess regulation of macrophage antigen processing and presentation Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002616 GO:0099525 biolink:BiologicalProcess presynaptic dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels. go-plus.json http://purl.obolibrary.org/obo/GO_0099525 goslim_synapse GO:0002617 biolink:BiologicalProcess negative regulation of macrophage antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation. go-plus.json down-regulation of macrophage antigen processing and presentation|downregulation of macrophage antigen processing and presentation|down regulation of macrophage antigen processing and presentation|inhibition of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002617 GO:0099577 biolink:BiologicalProcess regulation of translation at presynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099577 goslim_synapse GO:0099578 biolink:BiologicalProcess regulation of translation at postsynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099578 goslim_synapse GO:0099575 biolink:BiologicalProcess regulation of protein catabolic process at presynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099575 goslim_synapse CHEBI:51549 biolink:ChemicalSubstance benzisoxazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_51549 GO:0099576 biolink:BiologicalProcess regulation of protein catabolic process at postsynapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099576 goslim_synapse GO:0099573 biolink:CellularComponent glutamatergic postsynaptic density The post-synaptic specialization of a glutamatergic excitatory synapse. go-plus.json postsynaptic specialization, glutamatergic neuron-to-neuron synapse http://purl.obolibrary.org/obo/GO_0099573 goslim_synapse CHEBI:26587 biolink:ChemicalSubstance rutinoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_26587 GO:0099574 biolink:BiologicalProcess regulation of protein catabolic process at synapse, modulating synaptic transmission Any process that modulates synaptic transmission by regulating protein degradation at the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099574 goslim_synapse CHEBI:26588 biolink:ChemicalSubstance 1,3,5-triazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26588 GO:0099571 biolink:CellularComponent postsynaptic cytoskeleton The portion of the cytoskeleton contained within the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099571 goslim_synapse CHEBI:51545 biolink:ChemicalSubstance 1,2-benzoxazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_51545 GO:0099572 biolink:CellularComponent postsynaptic specialization A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. go-plus.json http://purl.obolibrary.org/obo/GO_0099572 goslim_synapse CHEBI:26580 biolink:ChemicalSubstance rifamycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26580 GO:0099579 biolink:MolecularActivity G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential. go-plus.json G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0099579 goslim_synapse GO:0099588 biolink:BiologicalProcess positive regulation of postsynaptic cytosolic calcium concentration Any process that increases the concentration of calcium ions in the postsynaptic cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0099588 goslim_synapse GO:0099589 biolink:MolecularActivity serotonin receptor activity Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0099589 GO:0099586 biolink:BiologicalProcess release of sequestered calcium ion into postsynaptic cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0099586 goslim_synapse GO:0099587 biolink:BiologicalProcess inorganic ion import across plasma membrane The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json inorganic ion import into cell http://purl.obolibrary.org/obo/GO_0099587 GO:0099585 biolink:BiologicalProcess release of sequestered calcium ion into presynaptic cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0099585 goslim_synapse GO:0099582 biolink:MolecularActivity neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol. go-plus.json neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099582 goslim_synapse GO:0099583 biolink:MolecularActivity neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol. go-plus.json neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099583 goslim_synapse GO:0099580 biolink:MolecularActivity ion antiporter activity involved in regulation of postsynaptic membrane potential Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. go-plus.json ion antiporter activity involved in regulation of post-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099580 goslim_synapse GO:0099581 biolink:MolecularActivity ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. go-plus.json ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099581 goslim_synapse CHEBI:26596 biolink:ChemicalSubstance salicylates go-plus.json http://purl.obolibrary.org/obo/CHEBI_26596 CHEBI:26590 biolink:ChemicalSubstance sabinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26590 chebi_ph7_3 GO:0099555 biolink:BiologicalProcess trans-synaptic signaling by nitric oxide, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099555 goslim_synapse GO:0099556 biolink:BiologicalProcess trans-synaptic signaling by carbon monoxide, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099556 goslim_synapse GO:0099553 biolink:BiologicalProcess trans-synaptic signaling by endocannabinoid, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099553 goslim_synapse GO:0099554 biolink:BiologicalProcess trans-synaptic signaling by soluble gas, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099554 goslim_synapse GO:0099551 biolink:BiologicalProcess trans-synaptic signaling by neuropeptide, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099551 goslim_synapse GO:0099552 biolink:BiologicalProcess trans-synaptic signaling by lipid, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099552 goslim_synapse GO:0099550 biolink:BiologicalProcess trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099550 goslim_synapse CHEBI:26568 biolink:ChemicalSubstance ribosylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26568 CHEBI:26561 biolink:ChemicalSubstance ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26561 CHEBI:26562 biolink:ChemicalSubstance ribose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26562 CHEBI:26563 biolink:ChemicalSubstance ribose triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26563 GO:0099559 biolink:BiologicalProcess maintenance of alignment of postsynaptic density and presynaptic active zone The process by which alignment between postsynaptic density and presynaptic active zone is maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0099559 goslim_synapse GO:0099557 biolink:BiologicalProcess trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099557 goslim_synapse GO:0099558 biolink:BiologicalProcess maintenance of synapse structure A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds. go-plus.json synaptic maintenance http://purl.obolibrary.org/obo/GO_0099558 goslim_synapse GO:0099566 biolink:BiologicalProcess regulation of postsynaptic cytosolic calcium ion concentration Any process that regulates the concentration of calcium in the postsynaptic cytosol. go-plus.json regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099566 goslim_synapse GO:0099567 biolink:MolecularActivity calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations. go-plus.json regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering|postsynaptic calcium ion buffering|calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099567 goslim_synapse GO:0099564 biolink:BiologicalProcess modification of synaptic structure, modulating synaptic transmission Any process that modulates synaptic transmission via modification of the structure of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099564 goslim_synapse GO:0099565 biolink:BiologicalProcess chemical synaptic transmission, postsynaptic The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. go-plus.json postsynaptic process involved in chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0099565 goslim_synapse|gocheck_do_not_annotate CHEBI:51510 biolink:ChemicalSubstance (S)-benzoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_51510 chebi_ph7_3 GO:0099562 biolink:BiologicalProcess maintenance of postsynaptic density structure A process which maintains the organization and the arrangement of proteins in the presynaptic density. go-plus.json http://purl.obolibrary.org/obo/GO_0099562 goslim_synapse GO:0099563 biolink:BiologicalProcess modification of synaptic structure Any process that modifies the structure/morphology of a synapse. go-plus.json synapse remodelling http://purl.obolibrary.org/obo/GO_0099563 goslim_synapse GO:0099560 biolink:BiologicalProcess synaptic membrane adhesion The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane. go-plus.json synapse adhesion between pre- and post-synapse http://purl.obolibrary.org/obo/GO_0099560 goslim_synapse GO:0099561 biolink:BiologicalProcess synaptic membrane adhesion to extracellular matrix The binding of a synaptic membrane to the extracellular matrix via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0099561 goslim_synapse CHEBI:26573 biolink:ChemicalSubstance ribulose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26573 GO:0099568 biolink:CellularComponent cytoplasmic region Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0099568 gocheck_do_not_annotate GO:0099569 biolink:CellularComponent presynaptic cytoskeleton The portion of the cytoskeleton contained within the presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099569 goslim_synapse GO:0002588 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. go-plus.json upregulation of antigen processing and presentation of peptide antigen via MHC class II|up regulation of antigen processing and presentation of peptide antigen via MHC class II|activation of antigen processing and presentation of peptide antigen via MHC class II|stimulation of antigen processing and presentation of peptide antigen via MHC class II|positive regulation of peptide antigen processing and presentation via MHC class II|up-regulation of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002588 GO:0051511 biolink:BiologicalProcess negative regulation of unidimensional cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. go-plus.json down-regulation of unidimensional cell growth|downregulation of unidimensional cell growth|negative regulation of cell elongation|down regulation of unidimensional cell growth|inhibition of unidimensional cell growth http://purl.obolibrary.org/obo/GO_0051511 GO:0002589 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. go-plus.json regulation of peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_0002589 GO:0051512 biolink:BiologicalProcess positive regulation of unidimensional cell growth Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. go-plus.json up regulation of unidimensional cell growth|positive regulation of cell elongation|upregulation of unidimensional cell growth|stimulation of unidimensional cell growth|up-regulation of unidimensional cell growth|activation of unidimensional cell growth http://purl.obolibrary.org/obo/GO_0051512 GO:0051510 biolink:BiologicalProcess regulation of unidimensional cell growth Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. go-plus.json regulation of cell elongation http://purl.obolibrary.org/obo/GO_0051510 GO:0002584 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen. go-plus.json downregulation of antigen processing and presentation of peptide antigen|down regulation of antigen processing and presentation of peptide antigen|inhibition of antigen processing and presentation of peptide antigen|down-regulation of antigen processing and presentation of peptide antigen|negative regulation of peptide antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002584 GO:0051515 biolink:BiologicalProcess positive regulation of monopolar cell growth Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. go-plus.json up regulation of monopolar cell growth|stimulation of monopolar cell growth|up-regulation of monopolar cell growth|upregulation of monopolar cell growth http://purl.obolibrary.org/obo/GO_0051515 GO:0051516 biolink:BiologicalProcess regulation of bipolar cell growth Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051516 GO:0002585 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen. go-plus.json upregulation of antigen processing and presentation of peptide antigen|stimulation of antigen processing and presentation of peptide antigen|up-regulation of antigen processing and presentation of peptide antigen|activation of antigen processing and presentation of peptide antigen|positive regulation of peptide antigen processing and presentation|up regulation of antigen processing and presentation of peptide antigen http://purl.obolibrary.org/obo/GO_0002585 GO:0051513 biolink:BiologicalProcess regulation of monopolar cell growth Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051513 GO:0002586 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. go-plus.json regulation of peptide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002586 GO:0002587 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. go-plus.json down regulation of antigen processing and presentation of peptide antigen via MHC class II|downregulation of antigen processing and presentation of peptide antigen via MHC class II|negative regulation of peptide antigen processing and presentation via MHC class II|down-regulation of antigen processing and presentation of peptide antigen via MHC class II|inhibition of antigen processing and presentation of peptide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002587 GO:0051514 biolink:BiologicalProcess negative regulation of monopolar cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. go-plus.json down-regulation of monopolar cell growth|inhibition of monopolar cell growth|down regulation of monopolar cell growth|downregulation of monopolar cell growth http://purl.obolibrary.org/obo/GO_0051514 GO:0002580 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. go-plus.json regulation of peptide or polysaccharide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002580 GO:0051519 biolink:BiologicalProcess activation of bipolar cell growth Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051519 GO:0002581 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. go-plus.json down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002581 GO:0051517 biolink:BiologicalProcess negative regulation of bipolar cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. go-plus.json down regulation of bipolar cell growth|downregulation of bipolar cell growth|down-regulation of bipolar cell growth|inhibition of bipolar cell growth http://purl.obolibrary.org/obo/GO_0051517 GO:0002582 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. go-plus.json upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002582 GO:0002583 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen. go-plus.json regulation of peptide antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002583 GO:0051518 biolink:BiologicalProcess positive regulation of bipolar cell growth Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. go-plus.json up regulation of bipolar cell growth|stimulation of bipolar cell growth|up-regulation of bipolar cell growth|upregulation of bipolar cell growth http://purl.obolibrary.org/obo/GO_0051518 GO:1905920 biolink:BiologicalProcess positive regulation of CoA-transferase activity Any process that activates or increases the frequency, rate or extent of CoA-transferase activity. go-plus.json up regulation of CoA-transferase activity|upregulation of CoA-transferase activity|up-regulation of CoA-transferase activity|activation of CoA-transferase activity http://purl.obolibrary.org/obo/GO_1905920 GO:1905921 biolink:BiologicalProcess regulation of acetylcholine biosynthetic process Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. go-plus.json regulation of acetylcholine synthesis|regulation of acetylcholine formation|regulation of acetylcholine biosynthesis|regulation of acetylcholine anabolism http://purl.obolibrary.org/obo/GO_1905921 GO:1905922 biolink:BiologicalProcess negative regulation of acetylcholine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. go-plus.json downregulation of acetylcholine anabolism|down regulation of acetylcholine synthesis|down regulation of acetylcholine formation|downregulation of acetylcholine synthesis|downregulation of acetylcholine formation|down-regulation of acetylcholine anabolism|negative regulation of acetylcholine anabolism|down-regulation of acetylcholine biosynthetic process|down-regulation of acetylcholine synthesis|negative regulation of acetylcholine synthesis|negative regulation of acetylcholine biosynthesis|down-regulation of acetylcholine biosynthesis|inhibition of acetylcholine anabolism|down-regulation of acetylcholine formation|negative regulation of acetylcholine formation|inhibition of acetylcholine synthesis|downregulation of acetylcholine biosynthetic process|downregulation of acetylcholine biosynthesis|inhibition of acetylcholine formation|down regulation of acetylcholine biosynthesis|down regulation of acetylcholine biosynthetic process|inhibition of acetylcholine biosynthetic process|inhibition of acetylcholine biosynthesis|down regulation of acetylcholine anabolism http://purl.obolibrary.org/obo/GO_1905922 GO:1905923 biolink:BiologicalProcess positive regulation of acetylcholine biosynthetic process Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. go-plus.json upregulation of acetylcholine formation|up regulation of acetylcholine anabolism|activation of acetylcholine anabolism|positive regulation of acetylcholine anabolism|up-regulation of acetylcholine biosynthesis|up-regulation of acetylcholine biosynthetic process|activation of acetylcholine biosynthesis|activation of acetylcholine biosynthetic process|up regulation of acetylcholine synthesis|activation of acetylcholine synthesis|positive regulation of acetylcholine synthesis|up regulation of acetylcholine formation|activation of acetylcholine formation|positive regulation of acetylcholine formation|up-regulation of acetylcholine anabolism|positive regulation of acetylcholine biosynthesis|up regulation of acetylcholine biosynthetic process|up regulation of acetylcholine biosynthesis|up-regulation of acetylcholine synthesis|up-regulation of acetylcholine formation|upregulation of acetylcholine anabolism|upregulation of acetylcholine biosynthesis|upregulation of acetylcholine biosynthetic process|upregulation of acetylcholine synthesis http://purl.obolibrary.org/obo/GO_1905923 GO:1905924 biolink:BiologicalProcess obsolete regulation of invadopodium assembly OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium assembly. go-plus.json regulation of invadopodium formation http://purl.obolibrary.org/obo/GO_1905924 GO:1905925 biolink:BiologicalProcess obsolete negative regulation of invadopodium assembly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium assembly. go-plus.json down regulation of invadopodium assembly|downregulation of invadopodium formation|downregulation of invadopodium assembly|down regulation of invadopodium formation|inhibition of invadopodium formation|down-regulation of invadopodium assembly|inhibition of invadopodium assembly|down-regulation of invadopodium formation|negative regulation of invadopodium formation http://purl.obolibrary.org/obo/GO_1905925 GO:1905926 biolink:BiologicalProcess obsolete positive regulation of invadopodium assembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium assembly. go-plus.json up regulation of invadopodium formation|up regulation of invadopodium assembly|upregulation of invadopodium formation|activation of invadopodium assembly|up-regulation of invadopodium formation|activation of invadopodium formation|up-regulation of invadopodium assembly|positive regulation of invadopodium formation|upregulation of invadopodium assembly http://purl.obolibrary.org/obo/GO_1905926 GO:1905927 biolink:BiologicalProcess obsolete regulation of invadopodium disassembly OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium disassembly. go-plus.json http://purl.obolibrary.org/obo/GO_1905927 GO:1905928 biolink:BiologicalProcess obsolete negative regulation of invadopodium disassembly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly. go-plus.json downregulation of invadopodium disassembly|down regulation of invadopodium disassembly|inhibition of invadopodium disassembly|down-regulation of invadopodium disassembly http://purl.obolibrary.org/obo/GO_1905928 GO:1905929 biolink:BiologicalProcess obsolete positive regulation of invadopodium disassembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium disassembly. go-plus.json upregulation of invadopodium disassembly|up-regulation of invadopodium disassembly|activation of invadopodium disassembly|up regulation of invadopodium disassembly http://purl.obolibrary.org/obo/GO_1905929 GO:0002599 biolink:BiologicalProcess negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. go-plus.json negative regulation of lipid antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|inhibition of antigen processing and presentation of lipid antigen via MHC class Ib|down regulation of antigen processing and presentation of lipid antigen via MHC class Ib|downregulation of antigen processing and presentation of lipid antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002599 GO:0051522 biolink:BiologicalProcess activation of monopolar cell growth Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051522 GO:0051523 biolink:BiologicalProcess cell growth mode switching, monopolar to bipolar The process in which a cell switches from monopolar cell growth to bipolar cell growth. go-plus.json new end take off|NETO http://purl.obolibrary.org/obo/GO_0051523 GO:0051520 biolink:BiologicalProcess termination of bipolar cell growth Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051520 GO:0051521 biolink:BiologicalProcess termination of monopolar cell growth Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051521 GO:0051526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051526 GO:0002595 biolink:BiologicalProcess regulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. go-plus.json regulation of peptide antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002595 GO:0002596 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. go-plus.json negative regulation of peptide antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|inhibition of antigen processing and presentation of peptide antigen via MHC class Ib|down regulation of antigen processing and presentation of peptide antigen via MHC class Ib|downregulation of antigen processing and presentation of peptide antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002596 GO:0051527 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051527 PR:000013246 biolink:Protein prolactin A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof. go-plus.json PRL http://purl.obolibrary.org/obo/PR_000013246 GO:0002597 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. go-plus.json up regulation of antigen processing and presentation of peptide antigen via MHC class Ib|activation of antigen processing and presentation of peptide antigen via MHC class Ib|positive regulation of peptide antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation of peptide antigen via MHC class Ib|up-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|upregulation of antigen processing and presentation of peptide antigen via MHC class Ib http://purl.obolibrary.org/obo/GO_0002597 GO:0051524 biolink:BiologicalProcess cell growth mode switching, bipolar to monopolar The process in which a cell switches from bipolar cell growth to monopolar cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0051524 GO:0051525 biolink:MolecularActivity NFAT protein binding Binding to NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system. go-plus.json NFATx binding|NFAT5 protein binding|nuclear factor of activated T cell protein binding|NFAT4 protein binding|NFAT3 protein binding|NFAT2 protein binding|NFAT1 protein binding|NFATp binding|NFAT binding|NFATc4 binding|NFATc3 binding|NFATc2 binding|NFATc1 binding|NFATc binding|non-calcium-regulated NFAT protein binding http://purl.obolibrary.org/obo/GO_0051525 PR:000013248 biolink:Protein prolactin receptor A protein that is a translation product of the human PRLR gene or a 1:1 ortholog thereof. go-plus.json PRL-R|PRLR http://purl.obolibrary.org/obo/PR_000013248 GO:0002598 biolink:BiologicalProcess regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. go-plus.json regulation of lipid antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002598 GO:0002591 biolink:BiologicalProcess positive regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. go-plus.json stimulation of antigen processing and presentation of peptide antigen via MHC class I|activation of antigen processing and presentation of peptide antigen via MHC class I|up-regulation of antigen processing and presentation of peptide antigen via MHC class I|positive regulation of peptide antigen processing and presentation via MHC class I|up regulation of antigen processing and presentation of peptide antigen via MHC class I|upregulation of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002591 GO:0002592 biolink:BiologicalProcess regulation of antigen processing and presentation via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. go-plus.json http://purl.obolibrary.org/obo/GO_0002592 GO:0051528 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051528 GO:0002593 biolink:BiologicalProcess negative regulation of antigen processing and presentation via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. go-plus.json down-regulation of antigen processing and presentation via MHC class Ib|downregulation of antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation via MHC class Ib|inhibition of antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002593 GO:0002594 biolink:BiologicalProcess positive regulation of antigen processing and presentation via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. go-plus.json upregulation of antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation via MHC class Ib|up-regulation of antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation via MHC class Ib|up regulation of antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002594 GO:0051529 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051529 GO:0002590 biolink:BiologicalProcess negative regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. go-plus.json down-regulation of antigen processing and presentation of peptide antigen via MHC class I|negative regulation of peptide antigen processing and presentation via MHC class I|downregulation of antigen processing and presentation of peptide antigen via MHC class I|down regulation of antigen processing and presentation of peptide antigen via MHC class I|inhibition of antigen processing and presentation of peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002590 GO:1905930 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. go-plus.json regulation of VSMC differentiation involved in phenotypic switching|regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of VSMC differentiation involved in phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1905930 GO:1905931 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. go-plus.json inhibition of VSMC differentiation involved in phenotypic switching|down regulation of VSMC differentiation involved in phenotypic dimorphism|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of VSMC differentiation involved in phenotypic switching|downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|downregulation of VSMC differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic dimorphism|down-regulation of VSMC differentiation involved in phenotypic dimorphism|down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|negative regulation of VSMC differentiation involved in phenotypic switching|down-regulation of VSMC differentiation involved in phenotypic switching|downregulation of VSMC differentiation involved in phenotypic dimorphism|downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1905931 GO:1905932 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. go-plus.json activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|activation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|upregulation of VSMC differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic dimorphism|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of VSMC differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic dimorphism|up regulation of VSMC differentiation involved in phenotypic dimorphism|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching http://purl.obolibrary.org/obo/GO_1905932 GO:1905933 biolink:BiologicalProcess regulation of cell fate determination Any process that modulates the frequency, rate or extent of cell fate determination. go-plus.json http://purl.obolibrary.org/obo/GO_1905933 GO:1905934 biolink:BiologicalProcess negative regulation of cell fate determination Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination. go-plus.json inhibition of cell fate determination|down regulation of cell fate determination|downregulation of cell fate determination|down-regulation of cell fate determination http://purl.obolibrary.org/obo/GO_1905934 GO:1905935 biolink:BiologicalProcess positive regulation of cell fate determination Any process that activates or increases the frequency, rate or extent of cell fate determination. go-plus.json up-regulation of cell fate determination|upregulation of cell fate determination|up regulation of cell fate determination|activation of cell fate determination http://purl.obolibrary.org/obo/GO_1905935 GO:1905936 biolink:BiologicalProcess regulation of germ cell proliferation Any process that modulates the frequency, rate or extent of germ cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_1905936 GO:1905937 biolink:BiologicalProcess negative regulation of germ cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. go-plus.json down regulation of germ cell proliferation|downregulation of germ cell proliferation|down-regulation of germ cell proliferation|inhibition of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905937 GO:1905938 biolink:BiologicalProcess positive regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. go-plus.json upregulation of germ cell proliferation|up regulation of germ cell proliferation|activation of germ cell proliferation|up-regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905938 GO:1905939 biolink:BiologicalProcess regulation of gonad development Any process that modulates the frequency, rate or extent of gonad development. go-plus.json regulation of gonadogenesis http://purl.obolibrary.org/obo/GO_1905939 GO:0051533 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051533 GO:0002566 biolink:BiologicalProcess somatic diversification of immune receptors via somatic mutation The process in which immune receptor genes are diversified through somatic mutation. go-plus.json http://purl.obolibrary.org/obo/GO_0002566 GO:0051534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051534 GO:0002567 biolink:BiologicalProcess somatic diversification of FREP-based immune receptors The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails. go-plus.json http://purl.obolibrary.org/obo/GO_0002567 GO:0075501 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075501 GO:0075502 biolink:BiologicalProcess endosome membrane permeabilization involved in viral entry into host cell Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm. go-plus.json viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization http://purl.obolibrary.org/obo/GO_0075502 GO:0002568 biolink:BiologicalProcess somatic diversification of T cell receptor genes The somatic process that results in the generation of sequence diversity of T cell receptor genes. go-plus.json somatic diversification of TCR genes http://purl.obolibrary.org/obo/GO_0002568 GO:0051531 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051531 GO:0051532 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051532 GO:0075503 biolink:BiologicalProcess fusion of virus membrane with host macropinosome membrane Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm. go-plus.json viral entry into host cell via macropinocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via macropinocytosis followed by membrane fusion with the host macropinosome membrane http://purl.obolibrary.org/obo/GO_0075503 GO:0002569 biolink:BiologicalProcess somatic diversification of immune receptors by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene. go-plus.json http://purl.obolibrary.org/obo/GO_0002569 GO:0002562 biolink:BiologicalProcess somatic diversification of immune receptors via germline recombination within a single locus The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. go-plus.json http://purl.obolibrary.org/obo/GO_0002562 GO:0051537 biolink:MolecularActivity 2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. go-plus.json 2 iron, 2 sulphur cluster binding|diiron disulphide cluster binding|2Fe-2S cluster binding|diiron disulfide cluster binding|2 Fe 2 S cluster binding|iron-sulphur cluster 2Fe-2S binding|iron-sulfur cluster 2Fe-2S binding http://purl.obolibrary.org/obo/GO_0051537 GO:0075504 biolink:BiologicalProcess macropinosomal membrane permeabilization involved in viral entry into host cell Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm. go-plus.json viral entry into host cell via macropinocytosis followed by macropinosomal membrane permeabilization http://purl.obolibrary.org/obo/GO_0075504 GO:0051538 biolink:MolecularActivity 3 iron, 4 sulfur cluster binding Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing. go-plus.json triiron tetrasulfide cluster binding|iron-sulfur cluster 3Fe-4S binding|3Fe-4S cluster binding|3 Fe 4 S cluster binding|triiron tetrasulphide cluster binding|iron-sulphur cluster 3Fe-4S binding|3 iron, 4 sulphur cluster binding http://purl.obolibrary.org/obo/GO_0051538 GO:0002563 biolink:BiologicalProcess somatic diversification of immune receptors via alternate splicing The process in which immune receptor genes are diversified through alternate splicing. go-plus.json http://purl.obolibrary.org/obo/GO_0002563 GO:0075505 biolink:BiologicalProcess entry of intact viral capsid into host nucleus through nuclear pore complex Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC). go-plus.json http://purl.obolibrary.org/obo/GO_0075505 GO:0002564 biolink:BiologicalProcess alternate splicing of immunoglobulin genes The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons. go-plus.json alternate splicing of antibody genes http://purl.obolibrary.org/obo/GO_0002564 GO:0051535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051535 GO:0075506 biolink:BiologicalProcess entry of viral genome into host nucleus through nuclear pore complex via importin Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery. go-plus.json entry of viral genome into host nucleus via cellular importin transport through the nuclear pore complex http://purl.obolibrary.org/obo/GO_0075506 GO:0051536 biolink:MolecularActivity iron-sulfur cluster binding Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms. go-plus.json iron sulphur cluster binding|iron-sulphur cluster binding|iron sulfur cluster binding|Fe/S binding http://purl.obolibrary.org/obo/GO_0051536 goslim_metagenomics GO:0002565 biolink:BiologicalProcess somatic diversification of immune receptors via gene conversion The process in which immune receptor genes are diversified through gene conversion. go-plus.json http://purl.obolibrary.org/obo/GO_0002565 GO:0075507 biolink:BiologicalProcess entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0075507 GO:0075508 biolink:BiologicalProcess entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm. go-plus.json entry of viral genome into host nucleus via attachment of capsid to nuclear pore complex and release of genome into nucleoplasm http://purl.obolibrary.org/obo/GO_0075508 GO:0075509 biolink:BiologicalProcess endocytosis involved in viral entry into host cell Any endocytosis that is involved in the uptake of a virus into a host cell. VZ:977 go-plus.json viral penetration via endocytosis followed by endosome disruption|virus endocytosis by host|viral entry into host cell via endocytosis http://purl.obolibrary.org/obo/GO_0075509 GO:0051539 biolink:MolecularActivity 4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. go-plus.json iron-sulfur cluster 4Fe-4S binding|tetrairon tetrasulfide cluster binding|4Fe-4S cluster binding|tetrairon tetrasulphide cluster binding|4 Fe 4 S cluster binding|iron-sulphur cluster 4Fe-4S binding|4 iron, 4 sulphur cluster binding http://purl.obolibrary.org/obo/GO_0051539 GO:0002560 biolink:BiologicalProcess basophil mediated immunity Any process involved in the carrying out of an immune response by a basophil. go-plus.json http://purl.obolibrary.org/obo/GO_0002560 GO:0002561 biolink:BiologicalProcess basophil degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. go-plus.json http://purl.obolibrary.org/obo/GO_0002561 GO:1905940 biolink:BiologicalProcess negative regulation of gonad development Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. go-plus.json down regulation of gonad development|down regulation of gonadogenesis|downregulation of gonad development|downregulation of gonadogenesis|down-regulation of gonad development|down-regulation of gonadogenesis|negative regulation of gonadogenesis|inhibition of gonad development|inhibition of gonadogenesis http://purl.obolibrary.org/obo/GO_1905940 GO:1905941 biolink:BiologicalProcess positive regulation of gonad development Any process that activates or increases the frequency, rate or extent of gonad development. go-plus.json upregulation of gonad development|upregulation of gonadogenesis|up regulation of gonad development|activation of gonad development|up regulation of gonadogenesis|activation of gonadogenesis|positive regulation of gonadogenesis|up-regulation of gonad development|up-regulation of gonadogenesis http://purl.obolibrary.org/obo/GO_1905941 GO:1905942 biolink:BiologicalProcess regulation of formation of growth cone in injured axon Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon. go-plus.json http://purl.obolibrary.org/obo/GO_1905942 GO:1905943 biolink:BiologicalProcess negative regulation of formation of growth cone in injured axon Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon. go-plus.json down-regulation of formation of growth cone in injured axon|downregulation of formation of growth cone in injured axon|down regulation of formation of growth cone in injured axon|inhibition of formation of growth cone in injured axon http://purl.obolibrary.org/obo/GO_1905943 GO:1905944 biolink:BiologicalProcess positive regulation of formation of growth cone in injured axon Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon. go-plus.json up-regulation of formation of growth cone in injured axon|activation of formation of growth cone in injured axon|up regulation of formation of growth cone in injured axon|upregulation of formation of growth cone in injured axon http://purl.obolibrary.org/obo/GO_1905944 GO:1905945 biolink:BiologicalProcess regulation of response to calcium ion Any process that modulates the frequency, rate or extent of response to calcium ion. go-plus.json regulation of response to Ca2+ ion http://purl.obolibrary.org/obo/GO_1905945 GO:1905946 biolink:BiologicalProcess negative regulation of response to calcium ion Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. go-plus.json downregulation of response to Ca2+ ion|downregulation of response to calcium ion|down regulation of response to Ca2+ ion|inhibition of response to Ca2+ ion|down-regulation of response to calcium ion|inhibition of response to calcium ion|negative regulation of response to Ca2+ ion|down-regulation of response to Ca2+ ion|down regulation of response to calcium ion http://purl.obolibrary.org/obo/GO_1905946 GO:1905947 biolink:BiologicalProcess positive regulation of response to calcium ion Any process that activates or increases the frequency, rate or extent of response to calcium ion. go-plus.json up regulation of response to Ca2+ ion|up regulation of response to calcium ion|activation of response to calcium ion|upregulation of response to Ca2+ ion|activation of response to Ca2+ ion|up-regulation of response to Ca2+ ion|up-regulation of response to calcium ion|upregulation of response to calcium ion|positive regulation of response to Ca2+ ion http://purl.obolibrary.org/obo/GO_1905947 GO:1905948 biolink:MolecularActivity ABC-type 3',5'-cyclic GMP transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out). go-plus.json ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity|ATPase-coupled cGMP transmembrane transporter activity|ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity|3',5'-cyclic GMP transmembrane-transporting ATPase activity http://purl.obolibrary.org/obo/GO_1905948 GO:1905949 biolink:BiologicalProcess negative regulation of calcium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane. go-plus.json inhibition of calcium ion import across plasma membrane|down regulation of calcium ion import across plasma membrane|downregulation of calcium ion import across plasma membrane|down-regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905949 GO:0051530 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051530 GO:0051544 biolink:BiologicalProcess positive regulation of elastin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. go-plus.json stimulation of elastin biosynthetic process|up-regulation of elastin biosynthetic process|activation of elastin biosynthetic process|up regulation of elastin biosynthetic process|upregulation of elastin biosynthetic process http://purl.obolibrary.org/obo/GO_0051544 GO:0002577 biolink:BiologicalProcess regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002577 GO:0002578 biolink:BiologicalProcess negative regulation of antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. go-plus.json down-regulation of antigen processing and presentation|inhibition of antigen processing and presentation|down regulation of antigen processing and presentation|downregulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002578 GO:0051545 biolink:BiologicalProcess negative regulation of elastin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. go-plus.json down-regulation of elastin biosynthetic process|downregulation of elastin biosynthetic process|down regulation of elastin biosynthetic process|inhibition of elastin biosynthetic process http://purl.obolibrary.org/obo/GO_0051545 GO:0002579 biolink:BiologicalProcess positive regulation of antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. go-plus.json stimulation of antigen processing and presentation|up-regulation of antigen processing and presentation|upregulation of antigen processing and presentation|up regulation of antigen processing and presentation|activation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002579 GO:0051542 biolink:BiologicalProcess elastin biosynthetic process The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries. go-plus.json http://purl.obolibrary.org/obo/GO_0051542 GO:0051543 biolink:BiologicalProcess regulation of elastin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. go-plus.json http://purl.obolibrary.org/obo/GO_0051543 GO:0051548 biolink:BiologicalProcess negative regulation of keratinocyte migration Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration. go-plus.json down-regulation of keratinocyte migration|downregulation of keratinocyte migration|down regulation of keratinocyte migration|inhibition of keratinocyte migration http://purl.obolibrary.org/obo/GO_0051548 GO:0002573 biolink:BiologicalProcess myeloid leukocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. go-plus.json myeloid leucocyte differentiation http://purl.obolibrary.org/obo/GO_0002573 GO:0051549 biolink:BiologicalProcess positive regulation of keratinocyte migration Any process that activates or increases the frequency, rate or extent of keratinocyte migration. go-plus.json up regulation of keratinocyte migration|upregulation of keratinocyte migration|stimulation of keratinocyte migration|activation of keratinocyte migration|up-regulation of keratinocyte migration http://purl.obolibrary.org/obo/GO_0051549 GO:0002574 biolink:BiologicalProcess thrombocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0002574 CHEBI:145656 biolink:ChemicalSubstance galactoxylomannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_145656 GO:0051546 biolink:BiologicalProcess keratinocyte migration The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_0051546 GO:0002575 biolink:BiologicalProcess basophil chemotaxis The movement of a basophil in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002575 GO:0051547 biolink:BiologicalProcess regulation of keratinocyte migration Any process that modulates the frequency, rate or extent of keratinocyte migration. go-plus.json http://purl.obolibrary.org/obo/GO_0051547 GO:0002576 biolink:BiologicalProcess platelet degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. go-plus.json platelet exocytosis http://purl.obolibrary.org/obo/GO_0002576 GO:0002570 biolink:BiologicalProcess somatic diversification of immunoglobulin genes by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions. go-plus.json somatic diversification of antibody genes by N region addition http://purl.obolibrary.org/obo/GO_0002570 GO:0002571 biolink:BiologicalProcess somatic diversification of T cell receptor genes by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene. go-plus.json somatic diversification of TCR genes by N region addition http://purl.obolibrary.org/obo/GO_0002571 GO:0002572 biolink:BiologicalProcess pro-T cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed. go-plus.json pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002572 GO:1905960 biolink:BiologicalProcess response to differentiation-inducing factor 2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus. go-plus.json response to DIF-2|response to DIF2|response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one http://purl.obolibrary.org/obo/GO_1905960 GO:1905950 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905950 GO:1905951 biolink:BiologicalProcess mitochondrion DNA recombination Any DNA recombination that takes place in mitochondrion. go-plus.json DNA recombination in mitochondria http://purl.obolibrary.org/obo/GO_1905951 GO:1905952 biolink:BiologicalProcess regulation of lipid localization Any process that modulates the frequency, rate or extent of lipid localization. go-plus.json regulation of lipid localisation http://purl.obolibrary.org/obo/GO_1905952 GO:1905953 biolink:BiologicalProcess negative regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. go-plus.json down-regulation of lipid localization|downregulation of lipid localisation|down regulation of lipid localisation|inhibition of lipid localisation|downregulation of lipid localization|down regulation of lipid localization|inhibition of lipid localization|negative regulation of lipid localisation|down-regulation of lipid localisation http://purl.obolibrary.org/obo/GO_1905953 GO:1905954 biolink:BiologicalProcess positive regulation of lipid localization Any process that activates or increases the frequency, rate or extent of lipid localization. go-plus.json up regulation of lipid localization|upregulation of lipid localisation|upregulation of lipid localization|up-regulation of lipid localisation|activation of lipid localisation|up-regulation of lipid localization|activation of lipid localization|positive regulation of lipid localisation|up regulation of lipid localisation http://purl.obolibrary.org/obo/GO_1905954 GO:1905955 biolink:BiologicalProcess negative regulation of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. go-plus.json down-regulation of endothelial tube morphogenesis|downregulation of endothelial tube morphogenesis|down regulation of endothelial tube morphogenesis|inhibition of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905955 GO:1905956 biolink:BiologicalProcess positive regulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. go-plus.json up-regulation of endothelial tube morphogenesis|activation of endothelial tube morphogenesis|up regulation of endothelial tube morphogenesis|upregulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905956 GO:1905957 biolink:BiologicalProcess regulation of cellular response to alcohol Any process that modulates the frequency, rate or extent of cellular response to alcohol. go-plus.json http://purl.obolibrary.org/obo/GO_1905957 GO:1905958 biolink:BiologicalProcess negative regulation of cellular response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol. go-plus.json downregulation of cellular response to alcohol|down regulation of cellular response to alcohol|inhibition of cellular response to alcohol|down-regulation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905958 GO:1905959 biolink:BiologicalProcess positive regulation of cellular response to alcohol Any process that activates or increases the frequency, rate or extent of cellular response to alcohol. go-plus.json up regulation of cellular response to alcohol|upregulation of cellular response to alcohol|up-regulation of cellular response to alcohol|activation of cellular response to alcohol http://purl.obolibrary.org/obo/GO_1905959 GO:0051540 biolink:MolecularActivity metal cluster binding Binding to a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters. go-plus.json http://purl.obolibrary.org/obo/GO_0051540 goslim_pir GO:0051541 biolink:BiologicalProcess elastin metabolic process The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue. go-plus.json elastin metabolism http://purl.obolibrary.org/obo/GO_0051541 GO:0075522 biolink:BiologicalProcess IRES-dependent viral translational initiation Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation. VZ:867 go-plus.json http://purl.obolibrary.org/obo/GO_0075522 GO:0002544 biolink:BiologicalProcess chronic inflammatory response Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response. go-plus.json http://purl.obolibrary.org/obo/GO_0002544 GO:0051555 biolink:BiologicalProcess flavonol biosynthetic process The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities. MetaCyc:PWY-3101 go-plus.json http://purl.obolibrary.org/obo/GO_0051555 GO:0075523 biolink:BiologicalProcess viral translational frameshifting A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins. VZ:860 go-plus.json ribosomal frameshifting involved in viral translation http://purl.obolibrary.org/obo/GO_0075523 GO:0002545 biolink:BiologicalProcess chronic inflammatory response to non-antigenic stimulus A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma. go-plus.json http://purl.obolibrary.org/obo/GO_0002545 GO:0051556 biolink:BiologicalProcess leucoanthocyanidin metabolic process The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids. MetaCyc:PWY1F-823 go-plus.json leucoanthocyanidin metabolism http://purl.obolibrary.org/obo/GO_0051556 GO:0002546 biolink:BiologicalProcess negative regulation of tissue kallikrein-kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade. go-plus.json down regulation of tissue kallikrein-kinin cascade|downregulation of tissue kallikrein-kinin cascade|negative regulation of glandular kallikrein-kinin cascade|down-regulation of tissue kallikrein-kinin cascade|inhibition of tissue kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002546 GO:0075524 biolink:BiologicalProcess ribosomal skipping A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue. VZ:914 go-plus.json http://purl.obolibrary.org/obo/GO_0075524 GO:0051553 biolink:BiologicalProcess flavone biosynthetic process The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone). go-plus.json 2-phenylchromone biosynthesis|2-phenylchromone biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthesis|2-phenyl-4H-1-benzopyran-4-one biosynthetic process http://purl.obolibrary.org/obo/GO_0051553 GO:0075525 biolink:BiologicalProcess viral translational termination-reinitiation A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF. VZ:858 go-plus.json viral translation involving termination re-initiation|viral translation involving translational stop-start|termination reinitiation involved in viral translation|viral translation involving termination-reinitiation http://purl.obolibrary.org/obo/GO_0075525 GO:0002547 biolink:BiologicalProcess positive regulation of tissue kallikrein-kinin cascade Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade. go-plus.json up regulation of tissue kallikrein-kinin cascade|activation of tissue kallikrein-kinin cascade|positive regulation of glandular kallikrein-kinin cascade|stimulation of tissue kallikrein-kinin cascade|up-regulation of tissue kallikrein-kinin cascade|upregulation of tissue kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002547 GO:0051554 biolink:BiologicalProcess flavonol metabolic process The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities. go-plus.json flavonol metabolism http://purl.obolibrary.org/obo/GO_0051554 GO:0002540 biolink:BiologicalProcess leukotriene production involved in inflammatory response The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json leukotriene production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002540 GO:0075526 biolink:BiologicalProcess cap snatching A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs. VZ:839 go-plus.json cap snatching involved in viral mRNA transcription http://purl.obolibrary.org/obo/GO_0075526 GO:0051559 biolink:BiologicalProcess phlobaphene biosynthetic process The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols. go-plus.json http://purl.obolibrary.org/obo/GO_0051559 GO:0075527 biolink:BiologicalProcess viral RNA editing The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon. VZ:857 go-plus.json RNA editing involved in viral mRNA transcription http://purl.obolibrary.org/obo/GO_0075527 GO:0002541 biolink:BiologicalProcess activation of plasma proteins involved in acute inflammatory response Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0002541 GO:0075528 biolink:BiologicalProcess modulation by virus of host immune response The process in which a virus effects a change in the host immune response. go-plus.json regulation by virus of host immune system process http://purl.obolibrary.org/obo/GO_0075528 GO:0051557 biolink:BiologicalProcess leucoanthocyanidin biosynthetic process The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids. go-plus.json http://purl.obolibrary.org/obo/GO_0051557 GO:0002542 biolink:BiologicalProcess Factor XII activation Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade. go-plus.json Hageman factor activation http://purl.obolibrary.org/obo/GO_0002542 GO:0075529 biolink:BiologicalProcess establishment of latency as a circular episome A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure. go-plus.json establishment of latency as a circular plasmid|establishment of circular plasmid latency http://purl.obolibrary.org/obo/GO_0075529 GO:0002543 biolink:BiologicalProcess activation of blood coagulation via clotting cascade Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot. go-plus.json activation of clotting cascade http://purl.obolibrary.org/obo/GO_0002543 GO:0051558 biolink:BiologicalProcess phlobaphene metabolic process The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols. go-plus.json phlobaphene metabolism http://purl.obolibrary.org/obo/GO_0051558 GO:1905961 biolink:CellularComponent protein-cysteine S-palmitoyltransferase complex A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity. go-plus.json Palmitoyltransferase ERF2/SHR5 complex|Palmitoyltransferase ERF2-SHR5 complex http://purl.obolibrary.org/obo/GO_1905961 GO:1905962 biolink:BiologicalProcess glutamatergic neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron. go-plus.json http://purl.obolibrary.org/obo/GO_1905962 GO:1905963 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905963 GO:1905964 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905964 GO:1905965 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905965 GO:0002548 biolink:BiologicalProcess monocyte chemotaxis The movement of a monocyte in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002548 GO:0051551 biolink:BiologicalProcess aurone biosynthetic process The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments. go-plus.json benzalcoumaran-3-one biosynthesis|benzalcoumaran-3-one biosynthetic process http://purl.obolibrary.org/obo/GO_0051551 GO:0051552 biolink:BiologicalProcess flavone metabolic process The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone). go-plus.json 2-phenyl-4H-1-benzopyran-4-one metabolism|flavone metabolism|2-phenyl-4H-1-benzopyran-4-one metabolic process|2-phenylchromone metabolic process|2-phenylchromone metabolism http://purl.obolibrary.org/obo/GO_0051552 GO:0002549 biolink:BiologicalProcess negative regulation of plasma kallikrein-kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade. go-plus.json downregulation of plasma kallikrein-kinin cascade|down-regulation of plasma kallikrein-kinin cascade|inhibition of plasma kallikrein-kinin cascade|down regulation of plasma kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002549 GO:0075520 biolink:BiologicalProcess actin-dependent intracellular transport of virus The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions. VZ:991 go-plus.json actin-dependent intracellular transport of viral material http://purl.obolibrary.org/obo/GO_0075520 GO:0051550 biolink:BiologicalProcess aurone metabolic process The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides. go-plus.json aurone metabolism|benzalcoumaran-3-one metabolic process|benzalcoumaran-3-one metabolism http://purl.obolibrary.org/obo/GO_0051550 GO:0075521 biolink:BiologicalProcess microtubule-dependent intracellular transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules. VZ:983 go-plus.json microtubule-dependent intracellular transport of viral material to nucleus http://purl.obolibrary.org/obo/GO_0075521 GO:0099500 biolink:BiologicalProcess vesicle fusion to plasma membrane Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. go-plus.json http://purl.obolibrary.org/obo/GO_0099500 GO:0051566 biolink:MolecularActivity anthocyanidin-3-glucoside rhamnosyltransferase activity Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP. go-plus.json 3RT activity|anthocyanidin 3-glucoside-rhamnosyltransferase activity http://purl.obolibrary.org/obo/GO_0051566 GO:0075511 biolink:BiologicalProcess macropinosome lysis involved in viral entry into host cell Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0075511 GO:0002555 biolink:BiologicalProcess histamine secretion by platelet The regulated release of histamine by a platelet or group of platelets. go-plus.json http://purl.obolibrary.org/obo/GO_0002555 GO:0051567 biolink:BiologicalProcess histone H3-K9 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone. go-plus.json histone lysine H3 K9 methylation|histone H3K9me|histone H3 K9 methylation http://purl.obolibrary.org/obo/GO_0051567 GO:0075512 biolink:BiologicalProcess clathrin-dependent endocytosis of virus by host cell Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus. VZ:957 go-plus.json viral penetration via clathrin-mediated endocytosis|viral entry into host cell via clathrin-mediated endocytosis followed by endosome lysis|viral entry into host cell via clathrin-mediated endocytosis|clathrin-mediated endocytosis of virus by host cell http://purl.obolibrary.org/obo/GO_0075512 GO:0099501 biolink:CellularComponent exocytic vesicle membrane The lipid bilayer surrounding an exocytic vesicle. go-plus.json secretory vesicle membrane http://purl.obolibrary.org/obo/GO_0099501 GO:0002556 biolink:BiologicalProcess serotonin secretion by basophil The regulated release of serotonin by a basophil or group of basophils. go-plus.json serotonin release by basophil http://purl.obolibrary.org/obo/GO_0002556 GO:0051564 biolink:BiologicalProcess positive regulation of smooth endoplasmic reticulum calcium ion concentration Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum. go-plus.json elevation of smooth endoplasmic reticulum calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration elevation|elevation of smooth ER calcium ion concentration|elevation of calcium ion concentration in smooth endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0051564 GO:0075513 biolink:BiologicalProcess caveolin-mediated endocytosis of virus by host cell Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus. VZ:976 go-plus.json viral penetration via caveolae-mediated endocytosis followed by endosome disruption|viral entry into host cell via caveolae-mediated endocytosis|viral entry into host cell via caveolin-mediated endocytosis http://purl.obolibrary.org/obo/GO_0075513 GO:0002557 biolink:BiologicalProcess histamine secretion by basophil The regulated release of histamine by a basophil or group of basophils. go-plus.json http://purl.obolibrary.org/obo/GO_0002557 GO:0075514 biolink:BiologicalProcess endosome lysis involved in viral entry into host cell Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm. go-plus.json viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis http://purl.obolibrary.org/obo/GO_0075514 GO:0051565 biolink:BiologicalProcess negative regulation of smooth endoplasmic reticulum calcium ion concentration Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum. go-plus.json smooth endoplasmic reticulum calcium ion concentration reduction|reduction of smooth ER calcium ion concentration|reduction of calcium ion concentration in smooth ER|reduction of calcium ion concentration in smooth endoplasmic reticulum|reduction of smooth endoplasmic reticulum calcium ion concentration|smooth ER calcium ion concentration reduction http://purl.obolibrary.org/obo/GO_0051565 GO:0002558 biolink:BiologicalProcess type I hypersensitivity mediated by mast cells An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. go-plus.json http://purl.obolibrary.org/obo/GO_0002558 GO:0075515 biolink:BiologicalProcess obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. go-plus.json viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane http://purl.obolibrary.org/obo/GO_0075515 GO:0002551 biolink:BiologicalProcess mast cell chemotaxis The movement of a mast cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002551 GO:0075516 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075516 GO:0002552 biolink:BiologicalProcess serotonin secretion by mast cell The regulated release of serotonin by a mast cell or group of mast cells. go-plus.json serotonin release by mast cell http://purl.obolibrary.org/obo/GO_0002552 GO:0075517 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075517 GO:0051568 biolink:BiologicalProcess histone H3-K4 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone. go-plus.json histone lysine H3 K4 methylation|histone H3K4me|histone H3 K4 methylation http://purl.obolibrary.org/obo/GO_0051568 GO:0002553 biolink:BiologicalProcess histamine secretion by mast cell The regulated release of histamine by a mast cell or group of mast cells. go-plus.json http://purl.obolibrary.org/obo/GO_0002553 GO:0051569 biolink:BiologicalProcess regulation of histone H3-K4 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. go-plus.json http://purl.obolibrary.org/obo/GO_0051569 GO:0075518 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075518 GO:0002554 biolink:BiologicalProcess serotonin secretion by platelet The regulated release of serotonin by a platelet or group of platelets. go-plus.json serotonin release by platelet http://purl.obolibrary.org/obo/GO_0002554 GO:0075519 biolink:BiologicalProcess microtubule-dependent intracellular transport of viral material The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0075519 GO:0002550 biolink:BiologicalProcess positive regulation of plasma kallikrein-kinin cascade Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade. go-plus.json upregulation of plasma kallikrein-kinin cascade|up regulation of plasma kallikrein-kinin cascade|activation of plasma kallikrein-kinin cascade|stimulation of plasma kallikrein-kinin cascade|up-regulation of plasma kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002550 GO:0099508 biolink:MolecularActivity voltage-gated ion channel activity involved in regulation of presynaptic membrane potential Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse. go-plus.json voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|voltage gated ion channel activity involved in regulation of presynaptic membrane potential|voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential|voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099508 goslim_synapse GO:0099509 biolink:BiologicalProcess regulation of presynaptic cytosolic calcium ion concentration Any process that regulates the concentration of calcium in the presynaptic cytosol. go-plus.json regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099509 goslim_synapse GO:0099506 biolink:BiologicalProcess synaptic vesicle transport along actin filament The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors. go-plus.json http://purl.obolibrary.org/obo/GO_0099506 goslim_synapse GO:0099507 biolink:MolecularActivity ligand-gated ion channel activity involved in regulation of presynaptic membrane potential Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. go-plus.json ligand gated ion channel activity involved in regulation of presynaptic membrane potential|ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential|ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential|ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099507 goslim_synapse GO:0051562 biolink:BiologicalProcess negative regulation of mitochondrial calcium ion concentration Any process that decreases the concentration of calcium ions in mitochondria. go-plus.json reduction of mitochondrial calcium ion concentration|reduction of calcium ion concentration in mitochondria|mitochondrial calcium ion concentration reduction|reduction of calcium ion concentration in mitochondrion http://purl.obolibrary.org/obo/GO_0051562 GO:0099504 biolink:BiologicalProcess synaptic vesicle cycle A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters. go-plus.json http://purl.obolibrary.org/obo/GO_0099504 goslim_synapse GO:0002559 biolink:BiologicalProcess type I hypersensitivity mediated by basophils An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. go-plus.json http://purl.obolibrary.org/obo/GO_0002559 GO:0051563 biolink:BiologicalProcess smooth endoplasmic reticulum calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings. go-plus.json regulation of smooth ER calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration regulation|smooth ER calcium ion concentration regulation|regulation of calcium ion concentration in smooth endoplasmic reticulum|calcium ion homeostasis in smooth ER|smooth ER calcium ion homeostasis|calcium ion homeostasis in smooth endoplasmic reticulum|regulation of calcium ion concentration in smooth ER|regulation of smooth endoplasmic reticulum calcium ion concentration http://purl.obolibrary.org/obo/GO_0051563 GO:0099505 biolink:BiologicalProcess regulation of presynaptic membrane potential Any process that modulates the potential difference across a presynaptic membrane. go-plus.json regulation of pre-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0099505 goslim_synapse GO:0051560 biolink:BiologicalProcess mitochondrial calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings. go-plus.json regulation of calcium ion concentration in mitochondria|calcium ion homeostasis in mitochondrion|mitochondrial calcium ion concentration regulation|calcium ion homeostasis in mitochondria|regulation of mitochondrial calcium ion concentration|regulation of calcium ion concentration in mitochondrion http://purl.obolibrary.org/obo/GO_0051560 GO:0099502 biolink:BiologicalProcess calcium-dependent activation of synaptic vesicle fusion The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099502 goslim_synapse GO:0075510 biolink:BiologicalProcess macropinocytosis involved in viral entry into host cell Any macropinocytosis that is involved in the uptake of a virus into a host cell. VZ:800 go-plus.json viral entry into host cell via macropinocytosis http://purl.obolibrary.org/obo/GO_0075510 GO:0051561 biolink:BiologicalProcess positive regulation of mitochondrial calcium ion concentration Any process that increases the concentration of calcium ions in mitochondria. go-plus.json elevation of calcium ion concentration in mitochondrion|mitochondrial calcium ion concentration elevation|elevation of mitochondrial calcium ion concentration|elevation of calcium ion concentration in mitochondria http://purl.obolibrary.org/obo/GO_0051561 GO:0099503 biolink:CellularComponent secretory vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. go-plus.json http://purl.obolibrary.org/obo/GO_0099503 goslim_drosophila GO:0002522 biolink:BiologicalProcess leukocyte migration involved in immune response The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. go-plus.json immune cell migration during immune response|immune cell trafficking during immune response|leukocyte trafficking during immune response|leucocyte migration during immune response|leucocyte trafficking during immune response http://purl.obolibrary.org/obo/GO_0002522 GO:0051577 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051577 GO:0002523 biolink:BiologicalProcess leukocyte migration involved in inflammatory response The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. go-plus.json leukocyte trafficking during inflammatory response|leucocyte migration during inflammatory response|leukocyte migration during inflammatory response|leucocyte trafficking during inflammatory response|immune cell migration during inflammatory response|immune cell trafficking during inflammatory response http://purl.obolibrary.org/obo/GO_0002523 GO:0051578 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051578 GO:0002524 biolink:BiologicalProcess hypersensitivity An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. Wikipedia:Hypersensitivity go-plus.json hypersensitivity response http://purl.obolibrary.org/obo/GO_0002524 GO:0051575 biolink:MolecularActivity 5'-deoxyribose-5-phosphate lyase activity Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site. go-plus.json dRP lyase activity|dRPase activity|5'-deoxyribose phosphate activity http://purl.obolibrary.org/obo/GO_0051575 GO:0002525 biolink:BiologicalProcess acute inflammatory response to non-antigenic stimulus An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma. go-plus.json http://purl.obolibrary.org/obo/GO_0002525 GO:0051576 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051576 GO:0002520 biolink:BiologicalProcess immune system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. go-plus.json http://purl.obolibrary.org/obo/GO_0002520 goslim_drosophila GO:0051579 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051579 GO:0002521 biolink:BiologicalProcess leukocyte differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. go-plus.json leucocyte differentiation|immune cell differentiation http://purl.obolibrary.org/obo/GO_0002521 GO:0051570 biolink:BiologicalProcess regulation of histone H3-K9 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. go-plus.json http://purl.obolibrary.org/obo/GO_0051570 GO:0002526 biolink:BiologicalProcess acute inflammatory response Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0002526 GO:0051573 biolink:BiologicalProcess negative regulation of histone H3-K9 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. go-plus.json down regulation of histone H3-K9 methylation|downregulation of histone H3-K9 methylation|down-regulation of histone H3-K9 methylation|inhibition of histone H3-K9 methylation http://purl.obolibrary.org/obo/GO_0051573 CHEBI:51480 biolink:ChemicalSubstance (5S)-albaflavenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_51480 chebi_ph7_3 GO:0051574 biolink:BiologicalProcess positive regulation of histone H3-K9 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. go-plus.json upregulation of histone H3-K9 methylation|up regulation of histone H3-K9 methylation|activation of histone H3-K9 methylation|stimulation of histone H3-K9 methylation|up-regulation of histone H3-K9 methylation http://purl.obolibrary.org/obo/GO_0051574 GO:0002527 biolink:BiologicalProcess vasodilation involved in acute inflammatory response An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response. go-plus.json vasodilation during acute inflammatory response http://purl.obolibrary.org/obo/GO_0002527 GO:0051571 biolink:BiologicalProcess positive regulation of histone H3-K4 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. go-plus.json upregulation of histone H3-K4 methylation|up regulation of histone H3-K4 methylation|activation of histone H3-K4 methylation|stimulation of histone H3-K4 methylation|up-regulation of histone H3-K4 methylation http://purl.obolibrary.org/obo/GO_0051571 GO:0002528 biolink:BiologicalProcess regulation of vascular permeability involved in acute inflammatory response Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response. go-plus.json regulation of vascular permeability during acute inflammatory response http://purl.obolibrary.org/obo/GO_0002528 GO:0002529 biolink:BiologicalProcess regulation of plasma kallikrein-kinin cascade Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0002529 GO:0051572 biolink:BiologicalProcess negative regulation of histone H3-K4 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. go-plus.json down regulation of histone H3-K4 methylation|downregulation of histone H3-K4 methylation|down-regulation of histone H3-K4 methylation|inhibition of histone H3-K4 methylation http://purl.obolibrary.org/obo/GO_0051572 GO:0051588 biolink:BiologicalProcess regulation of neurotransmitter transport Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051588 GO:0002533 biolink:BiologicalProcess lysosomal enzyme secretion involved in inflammatory response The regulated release of lysosomal enzymes by a cell as part of an inflammatory response. go-plus.json secretion of lysosomal enzymes involved in inflammatory response|lysosomal enzyme secretion involved in acute inflammatory response|secretion of lysosomal enzymes involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002533 GO:0051589 biolink:BiologicalProcess negative regulation of neurotransmitter transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json inhibition of neurotransmitter transport|down-regulation of neurotransmitter transport|downregulation of neurotransmitter transport|down regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051589 GO:0002534 biolink:BiologicalProcess cytokine production involved in inflammatory response The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json cytokine production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002534 gocheck_do_not_annotate GO:0002535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002535 GO:0051586 biolink:BiologicalProcess positive regulation of dopamine uptake involved in synaptic transmission Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell. go-plus.json up regulation of dopamine uptake involved in synaptic transmission|activation of dopamine uptake involved in synaptic transmission|stimulation of dopamine uptake involved in synaptic transmission|up-regulation of dopamine uptake involved in synaptic transmission|positive regulation of dopamine import involved in synaptic transmission|upregulation of dopamine uptake involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051586 GO:0002536 biolink:BiologicalProcess respiratory burst involved in inflammatory response A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels. go-plus.json respiratory burst involved in acute inflammatory response|oxidative burst during acute inflammatory response|production of reactive oxygen species during acute inflammatory response http://purl.obolibrary.org/obo/GO_0002536 GO:0051587 biolink:BiologicalProcess inhibition of dopamine uptake involved in synaptic transmission Any process that prevents the activation of the directed movement of dopamine into a cell. go-plus.json inhibition of dopamine import involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051587 GO:0002530 biolink:BiologicalProcess regulation of systemic arterial blood pressure involved in acute-phase response Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein. go-plus.json regulation of systemic arterial blood pressure during acute phase response|blood pressure regulation during acute phase response http://purl.obolibrary.org/obo/GO_0002530 CHEBI:51478 biolink:ChemicalSubstance albaflavenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_51478 chebi_ph7_3 GO:0002531 biolink:BiologicalProcess regulation of heart contraction involved in acute-phase response Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein. go-plus.json regulation of cardiac contraction during acute phase response|regulation of heart contraction during acute phase response http://purl.obolibrary.org/obo/GO_0002531 CHEBI:51479 biolink:ChemicalSubstance (5R)-albaflavenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_51479 chebi_ph7_3 GO:0002532 biolink:BiologicalProcess production of molecular mediator involved in inflammatory response The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json production of molecular mediator involved in acute inflammatory response|production of cellular mediator of acute inflammation http://purl.obolibrary.org/obo/GO_0002532 GO:0051580 biolink:BiologicalProcess regulation of neurotransmitter uptake Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. go-plus.json regulation of neurotransmitter import|regulation of neurotransmitter reuptake http://purl.obolibrary.org/obo/GO_0051580 goslim_synapse NCBITaxon:422676 biolink:OrganismalEntity Aconoidasida go-plus.json Hematozoa Vivier 1982 http://purl.obolibrary.org/obo/NCBITaxon_422676 GO:0051581 biolink:BiologicalProcess negative regulation of neurotransmitter uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. go-plus.json negative regulation of neurotransmitter import|down regulation of neurotransmitter uptake|downregulation of neurotransmitter uptake|down-regulation of neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051581 CHEBI:51475 biolink:ChemicalSubstance naphthohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51475 GO:0002537 biolink:BiologicalProcess nitric oxide production involved in inflammatory response The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json production of nitric oxide involved in inflammatory response|production of nitric oxide involved in acute inflammatory response|nitric oxide production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002537 GO:0051584 biolink:BiologicalProcess regulation of dopamine uptake involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell. go-plus.json regulation of dopamine import involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051584 GO:0075530 biolink:BiologicalProcess establishment of latency as a linear episome A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure. go-plus.json establishment of linear plasmid latency|establishment of latency as a linear plasmid http://purl.obolibrary.org/obo/GO_0075530 GO:0051585 biolink:BiologicalProcess negative regulation of dopamine uptake involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell. go-plus.json down regulation of dopamine uptake involved in synaptic transmission|downregulation of dopamine uptake involved in synaptic transmission|down-regulation of dopamine uptake involved in synaptic transmission|negative regulation of dopamine import involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051585 GO:0002538 biolink:BiologicalProcess arachidonic acid metabolite production involved in inflammatory response The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels. go-plus.json production of arachidonic acid metabolites involved in inflammatory response|arachidonic acid metabolite production involved in acute inflammatory response|production of arachidonic acid metabolites involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002538 GO:0002539 biolink:BiologicalProcess prostaglandin production involved in inflammatory response The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json prostaglandin production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002539 GO:0051582 biolink:BiologicalProcess positive regulation of neurotransmitter uptake Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. go-plus.json up-regulation of neurotransmitter uptake|positive regulation of neurotransmitter import|upregulation of neurotransmitter uptake|up regulation of neurotransmitter uptake|activation of neurotransmitter uptake|stimulation of neurotransmitter uptake http://purl.obolibrary.org/obo/GO_0051582 GO:0051583 biolink:BiologicalProcess dopamine uptake involved in synaptic transmission The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. go-plus.json dopamine import involved in synaptic transmission|dopamine reuptake involved in synaptic transmission http://purl.obolibrary.org/obo/GO_0051583 NCBITaxon:38820 biolink:OrganismalEntity Poales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_38820 CHEBI:75434 biolink:ChemicalSubstance phytyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75434 chebi_ph7_3 CHEBI:75431 biolink:ChemicalSubstance ghrelin go-plus.json http://purl.obolibrary.org/obo/CHEBI_75431 CHEBI:75448 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75448 chebi_ph7_3 CHEBI:75449 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75449 chebi_ph7_3 CHEBI:75447 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75447 chebi_ph7_3 PR:000003858 biolink:Protein aryl hydrocarbon receptor A protein that is a translation product of the human AHR gene or a 1:1 ortholog thereof. go-plus.json AhR|AHR|class E basic helix-loop-helix protein 76|bHLHe76|Ah receptor http://purl.obolibrary.org/obo/PR_000003858 CHEBI:75443 biolink:ChemicalSubstance 1-butyryl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75443 chebi_ph7_3 CHEBI:75457 biolink:ChemicalSubstance 2-linoleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75457 chebi_ph7_3 CHEBI:75450 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75450 chebi_ph7_3 CHEBI:75455 biolink:ChemicalSubstance 2-palmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75455 chebi_ph7_3 CHEBI:75456 biolink:ChemicalSubstance 2-stearoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75456 chebi_ph7_3 CHEBI:75468 biolink:ChemicalSubstance 1-octadecanoyl-2-[(9Z)-octadecenoyl]-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75468 chebi_ph7_3 CHEBI:75462 biolink:ChemicalSubstance 1-octanoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75462 chebi_ph7_3 CHEBI:75463 biolink:ChemicalSubstance 1-lauroyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75463 chebi_ph7_3 CHEBI:75466 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75466 chebi_ph7_3 CHEBI:75465 biolink:ChemicalSubstance 1-myristoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75465 chebi_ph7_3 CHEBI:75470 biolink:ChemicalSubstance 1-icosanoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75470 chebi_ph7_3 CHEBI:75471 biolink:ChemicalSubstance 1-linoleoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75471 chebi_ph7_3 CHEBI:75472 biolink:ChemicalSubstance 1-arachidonoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75472 chebi_ph7_3 CHEBI:75480 biolink:ChemicalSubstance Ins-1-P-Cer-A 42:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75480 chebi_ph7_3 CHEBI:75481 biolink:ChemicalSubstance Ins-1-P-Cer-A 44:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75481 chebi_ph7_3 CHEBI:75483 biolink:ChemicalSubstance phytyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75483 chebi_ph7_3 GO:1905900 biolink:BiologicalProcess negative regulation of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. go-plus.json down-regulation of smooth muscle tissue development|downregulation of smooth muscle tissue development|down regulation of smooth muscle tissue development|inhibition of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905900 GO:1905901 biolink:BiologicalProcess positive regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. go-plus.json activation of smooth muscle tissue development|up regulation of smooth muscle tissue development|upregulation of smooth muscle tissue development|up-regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905901 GO:1905902 biolink:BiologicalProcess regulation of mesoderm formation Any process that modulates the frequency, rate or extent of mesoderm formation. go-plus.json http://purl.obolibrary.org/obo/GO_1905902 GO:1905903 biolink:BiologicalProcess negative regulation of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. go-plus.json down-regulation of mesoderm formation|downregulation of mesoderm formation|down regulation of mesoderm formation|inhibition of mesoderm formation http://purl.obolibrary.org/obo/GO_1905903 GO:1905904 biolink:BiologicalProcess positive regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. go-plus.json up regulation of mesoderm formation|upregulation of mesoderm formation|activation of mesoderm formation|up-regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905904 NCBITaxon:2697495 biolink:OrganismalEntity Spiralia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2697495 GO:1905905 biolink:BiologicalProcess pharyngeal gland morphogenesis The developmental process by which a pharyngeal gland is generated and organized. go-plus.json glandulae pharyngeae morphogenesis|pharynx gland morphogenesis http://purl.obolibrary.org/obo/GO_1905905 GO:1905906 biolink:BiologicalProcess regulation of amyloid fibril formation Any process that modulates the frequency, rate or extent of amyloid fibril formation. go-plus.json regulation of amyloid fibril assembly|regulation of amyloid structure formation|regulation of amyloid structure assembly http://purl.obolibrary.org/obo/GO_1905906 GO:1905907 biolink:BiologicalProcess negative regulation of amyloid fibril formation Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation. go-plus.json downregulation of amyloid fibril assembly|down-regulation of amyloid structure assembly|negative regulation of amyloid structure assembly|inhibition of amyloid structure formation|down-regulation of amyloid fibril formation|down regulation of amyloid structure formation|downregulation of amyloid structure assembly|negative regulation of amyloid fibril assembly|down-regulation of amyloid fibril assembly|downregulation of amyloid structure formation|down regulation of amyloid structure assembly|downregulation of amyloid fibril formation|down regulation of amyloid fibril formation|inhibition of amyloid structure assembly|negative regulation of amyloid structure formation|inhibition of amyloid fibril assembly|down-regulation of amyloid structure formation|inhibition of amyloid fibril formation|down regulation of amyloid fibril assembly http://purl.obolibrary.org/obo/GO_1905907 GO:1905908 biolink:BiologicalProcess positive regulation of amyloid fibril formation Any process that activates or increases the frequency, rate or extent of amyloid fibril formation. go-plus.json activation of amyloid structure assembly|activation of amyloid fibril formation|up-regulation of amyloid fibril formation|up regulation of amyloid fibril assembly|positive regulation of amyloid structure assembly|upregulation of amyloid structure formation|positive regulation of amyloid fibril assembly|up regulation of amyloid structure assembly|activation of amyloid fibril assembly|up regulation of amyloid fibril formation|up regulation of amyloid structure formation|upregulation of amyloid structure assembly|up-regulation of amyloid fibril assembly|positive regulation of amyloid structure formation|activation of amyloid structure formation|upregulation of amyloid fibril formation|upregulation of amyloid fibril assembly|up-regulation of amyloid structure assembly|up-regulation of amyloid structure formation http://purl.obolibrary.org/obo/GO_1905908 GO:1905909 biolink:BiologicalProcess regulation of dauer entry Any process that modulates the frequency, rate or extent of dauer entry. go-plus.json regulation of nematode entry into dormancy http://purl.obolibrary.org/obo/GO_1905909 GO:0051500 biolink:MolecularActivity D-tyrosyl-tRNA(Tyr) deacylase activity Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0051500 GO:0051501 biolink:BiologicalProcess diterpene phytoalexin metabolic process The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units. go-plus.json diterpene phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0051501 GO:0051504 biolink:BiologicalProcess diterpene phytoalexin precursor biosynthetic process pathway A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins. MetaCyc:PWY-2981 go-plus.json diterpene phytoalexin precursor formation pathway|diterpene phytoalexin precursor anabolism pathway|diterpene phytoalexin precursor synthesis pathway http://purl.obolibrary.org/obo/GO_0051504 GO:0051505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051505 GO:0051502 biolink:BiologicalProcess diterpene phytoalexin biosynthetic process The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses. go-plus.json diterpene phytoalexin synthesis|diterpene phytoalexin formation|diterpene phytoalexin biosynthesis|diterpene phytoalexin anabolism http://purl.obolibrary.org/obo/GO_0051502 GO:0051503 biolink:BiologicalProcess adenine nucleotide transport The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051503 GO:0051508 biolink:MolecularActivity stigmasterol UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol. RHEA:61828|MetaCyc:RXN-12126 go-plus.json http://purl.obolibrary.org/obo/GO_0051508 GO:0051509 biolink:MolecularActivity tomatidine UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine. go-plus.json http://purl.obolibrary.org/obo/GO_0051509 GO:0051506 biolink:MolecularActivity ergosterol UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol. RHEA:61836|MetaCyc:RXN-16975) go-plus.json http://purl.obolibrary.org/obo/GO_0051506 GO:0051507 biolink:MolecularActivity beta-sitosterol UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol. RHEA:61832|MetaCyc:RXN-12128 go-plus.json http://purl.obolibrary.org/obo/GO_0051507 NCBITaxon:133551 biolink:OrganismalEntity Eleutherozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_133551 OBO:uberon/core#transitively_anteriorly_connected_to biolink:OntologyClass transitively anteriorly connected to . transitively_anteriorly_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to GO:1905910 biolink:BiologicalProcess negative regulation of dauer entry Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry. go-plus.json down regulation of dauer entry|downregulation of dauer entry|negative regulation of nematode entry into dormancy|down-regulation of nematode entry into dormancy|down-regulation of dauer entry|downregulation of nematode entry into dormancy|down regulation of nematode entry into dormancy|inhibition of dauer entry|inhibition of nematode entry into dormancy http://purl.obolibrary.org/obo/GO_1905910 GO:1905911 biolink:BiologicalProcess positive regulation of dauer entry Any process that activates or increases the frequency, rate or extent of dauer entry. go-plus.json upregulation of nematode entry into dormancy|upregulation of dauer entry|up-regulation of nematode entry into dormancy|activation of nematode entry into dormancy|up regulation of dauer entry|activation of dauer entry|positive regulation of nematode entry into dormancy|up regulation of nematode entry into dormancy|up-regulation of dauer entry http://purl.obolibrary.org/obo/GO_1905911 GO:1905912 biolink:BiologicalProcess regulation of calcium ion export across plasma membrane Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane. go-plus.json regulation of calcium ion efflux from cell|regulation of calcium ion export from cell http://purl.obolibrary.org/obo/GO_1905912 GO:1905913 biolink:BiologicalProcess negative regulation of calcium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane. go-plus.json downregulation of calcium ion export from cell|negative regulation of calcium ion efflux from cell|down-regulation of calcium ion efflux from cell|down regulation of calcium ion export from cell|inhibition of calcium ion export from cell|negative regulation of calcium ion export from cell|downregulation of calcium ion efflux from cell|down regulation of calcium ion efflux from cell|inhibition of calcium ion efflux from cell|down-regulation of calcium ion export from cell http://purl.obolibrary.org/obo/GO_1905913 GO:1905914 biolink:BiologicalProcess positive regulation of calcium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane. go-plus.json up regulation of calcium ion export from cell|positive regulation of calcium ion efflux from cell|up regulation of calcium ion efflux from cell|upregulation of calcium ion export from cell|positive regulation of calcium ion export from cell|up-regulation of calcium ion export from cell|upregulation of calcium ion efflux from cell|activation of calcium ion export from cell|up-regulation of calcium ion efflux from cell|activation of calcium ion efflux from cell http://purl.obolibrary.org/obo/GO_1905914 GO:1905915 biolink:BiologicalProcess regulation of cell differentiation involved in phenotypic switching Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching. go-plus.json http://purl.obolibrary.org/obo/GO_1905915 GO:1905916 biolink:BiologicalProcess negative regulation of cell differentiation involved in phenotypic switching Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching. go-plus.json down regulation of cell differentiation involved in phenotypic switching|downregulation of cell differentiation involved in phenotypic switching|down-regulation of cell differentiation involved in phenotypic switching|inhibition of cell differentiation involved in phenotypic switching http://purl.obolibrary.org/obo/GO_1905916 GO:1905917 biolink:BiologicalProcess positive regulation of cell differentiation involved in phenotypic switching Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching. go-plus.json upregulation of cell differentiation involved in phenotypic switching|up regulation of cell differentiation involved in phenotypic switching|activation of cell differentiation involved in phenotypic switching|up-regulation of cell differentiation involved in phenotypic switching http://purl.obolibrary.org/obo/GO_1905917 GO:1905918 biolink:BiologicalProcess regulation of CoA-transferase activity Any process that modulates the frequency, rate or extent of CoA-transferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905918 GO:1905919 biolink:BiologicalProcess negative regulation of CoA-transferase activity Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity. go-plus.json down regulation of CoA-transferase activity|inhibition of CoA-transferase activity|down-regulation of CoA-transferase activity|downregulation of CoA-transferase activity http://purl.obolibrary.org/obo/GO_1905919 CHEBI:26420 biolink:ChemicalSubstance pyridinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26420 CHEBI:26421 biolink:ChemicalSubstance pyridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26421 CHEBI:26437 biolink:ChemicalSubstance pyrimidine nucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26437 CHEBI:26438 biolink:ChemicalSubstance pyrimidine nucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26438 CHEBI:26439 biolink:ChemicalSubstance pyrimidine nucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26439 CHEBI:26433 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26433 CHEBI:26434 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26434 CHEBI:26435 biolink:ChemicalSubstance pyrimidine deoxyribonucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26435 CHEBI:26436 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26436 CHEBI:26432 biolink:ChemicalSubstance pyrimidine nucleobase go-plus.json http://purl.obolibrary.org/obo/CHEBI_26432 chebi_ph7_3 CHEBI:26404 biolink:ChemicalSubstance puromycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26404 CHEBI:26406 biolink:ChemicalSubstance N-substituted putrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26406 CHEBI:26407 biolink:ChemicalSubstance pyrans go-plus.json http://purl.obolibrary.org/obo/CHEBI_26407 CHEBI:26400 biolink:ChemicalSubstance purine ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26400 CHEBI:26401 biolink:ChemicalSubstance purines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26401 chebi_ph7_3 CHEBI:26416 biolink:ChemicalSubstance pyridine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26416 CHEBI:26413 biolink:ChemicalSubstance pyrethroid insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26413 CHEBI:26414 biolink:ChemicalSubstance pyridazinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26414 CHEBI:26410 biolink:ChemicalSubstance pyrazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_26410 NCBITaxon:4734 biolink:OrganismalEntity commelinids go-plus.json Commelinidae|Commeliniflorae http://purl.obolibrary.org/obo/NCBITaxon_4734 UBERON:6001059 biolink:AnatomicalEntity insect visual primordium go-plus.json P2 VisSys|optic lobe placode|optic lobe primordium http://purl.obolibrary.org/obo/UBERON_6001059 CHEBI:75402 biolink:ChemicalSubstance 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75402 chebi_ph7_3 CHEBI:75406 biolink:ChemicalSubstance 2-methyl-6-phytylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75406 chebi_ph7_3 CHEBI:75407 biolink:ChemicalSubstance 2,3-dimethyl-6-phytylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75407 chebi_ph7_3 CHEBI:75416 biolink:ChemicalSubstance EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75416 CHEBI:75414 biolink:ChemicalSubstance platelet-activating factor receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_75414 NCBITaxon:4710 biolink:OrganismalEntity Arecaceae go-plus.json palm family|palms|Palmae http://purl.obolibrary.org/obo/NCBITaxon_4710 NCBITaxon:4719 biolink:OrganismalEntity Phoenix go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4719 GO:0036093 biolink:BiologicalProcess germ cell proliferation The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0036093 GO:0036094 biolink:MolecularActivity small molecule binding Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0036094 goslim_agr|goslim_flybase_ribbon GO:0036095 biolink:BiologicalProcess obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json transcriptional activation of genes involved in invasive growth http://purl.obolibrary.org/obo/GO_0036095 GO:0036096 biolink:MolecularActivity obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA. go-plus.json exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA|3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0036096 GO:0036097 biolink:BiologicalProcess obsolete pre-miRNA 3'-end processing OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA. go-plus.json pre-miRNA 3'-end processing|miRNA 3'-end processing|microRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0036097 CHEBI:75411 biolink:ChemicalSubstance 2-methyl-6-geranylgeranyl-1,4-benzoquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75411 chebi_ph7_3 GO:0036098 biolink:BiologicalProcess male germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of male germ-line stem cells. go-plus.json http://purl.obolibrary.org/obo/GO_0036098 CHEBI:75412 biolink:ChemicalSubstance 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75412 chebi_ph7_3 GO:0036099 biolink:BiologicalProcess female germ-line stem cell population maintenance The process by which an organism or tissue maintains a population of female germ-line stem cells. go-plus.json http://purl.obolibrary.org/obo/GO_0036099 GO:0036090 biolink:BiologicalProcess cleavage furrow ingression Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed. go-plus.json cleavage furrow contraction http://purl.obolibrary.org/obo/GO_0036090 GO:0036091 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0036091 GO:0036092 biolink:BiologicalProcess phosphatidylinositol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position. go-plus.json phosphatidylinositol-3-phosphate anabolism|PtdIns3P biosynthesis|PI(3)P biosynthesis|phosphatidylinositol-3-phosphate synthesis|phosphatidylinositol-3-phosphate biosynthesis|phosphatidylinositol-3-phosphate formation http://purl.obolibrary.org/obo/GO_0036092 GO:0036082 biolink:MolecularActivity extracellular phenylacetaldehyde-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts. go-plus.json ionotropic phenylacetaldehyde receptor activity http://purl.obolibrary.org/obo/GO_0036082 GO:0036083 biolink:BiologicalProcess obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0036083 GO:0036084 biolink:BiologicalProcess GDP-fucose import into endoplasmic reticulum lumen The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-fucose import into endoplasmic reticulum|GDP-fucose transport into endoplasmic reticulum lumen|GDP-fucose transport across endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0036084 GO:0036085 biolink:BiologicalProcess GDP-fucose import into Golgi lumen The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-fucose import into Golgi|GDP-fucose transport across Golgi membrane|GDP-fucose transport into Golgi lumen http://purl.obolibrary.org/obo/GO_0036085 GO:0036086 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. go-plus.json positive regulation of transcription from RNA polymerase II promoter in response to iron deficiency http://purl.obolibrary.org/obo/GO_0036086 GO:0036087 biolink:CellularComponent glutathione synthase complex A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer. go-plus.json glutathione synthetase complex http://purl.obolibrary.org/obo/GO_0036087 GO:0036088 biolink:BiologicalProcess D-serine catabolic process The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. go-plus.json D-serine degradation|D-serine breakdown|D-serine catabolism http://purl.obolibrary.org/obo/GO_0036088 GO:0036089 biolink:BiologicalProcess cleavage furrow formation Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell. go-plus.json cleavage furrow positioning http://purl.obolibrary.org/obo/GO_0036089 GO:0002742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002742 GO:0002743 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002743 GO:0002744 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002744 NCBITaxon:4777 biolink:OrganismalEntity Peronosporaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4777 GO:0002745 biolink:BiologicalProcess antigen processing and presentation initiated by receptor mediated uptake of antigen Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0002745 NCBITaxon:4776 biolink:OrganismalEntity Peronosporales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4776 GO:0002740 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002740 GO:0002741 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002741 GO:0085008 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from microneme OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085008 GO:0061040 biolink:BiologicalProcess female gonad morphogenesis The process in which a female gonad is generated and organized. go-plus.json ovary morphogenesis http://purl.obolibrary.org/obo/GO_0061040 GO:1905890 biolink:BiologicalProcess regulation of cellular response to very-low-density lipoprotein particle stimulus Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. go-plus.json regulation of cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_1905890 GO:0085009 biolink:BiologicalProcess obsolete interaction with host mediated by symbiont secreted substance released from Maurer's cleft OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host mediated by symbiont secreted substance released from Maurers cleft http://purl.obolibrary.org/obo/GO_0085009 GO:0061041 biolink:BiologicalProcess regulation of wound healing Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. go-plus.json http://purl.obolibrary.org/obo/GO_0061041 GO:0085006 biolink:BiologicalProcess obsolete interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host mediated by symbiont secreted substance released from parasitophorous vacuole http://purl.obolibrary.org/obo/GO_0085006 GO:0061042 biolink:BiologicalProcess vascular wound healing Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_0061042 GO:1905891 biolink:BiologicalProcess regulation of cellular response to thapsigargin Any process that modulates the frequency, rate or extent of cellular response to thapsigargin. go-plus.json http://purl.obolibrary.org/obo/GO_1905891 GO:0061043 biolink:BiologicalProcess regulation of vascular wound healing Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_0061043 GO:1905892 biolink:BiologicalProcess negative regulation of cellular response to thapsigargin Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin. go-plus.json down-regulation of cellular response to thapsigargin|inhibition of cellular response to thapsigargin|down regulation of cellular response to thapsigargin|downregulation of cellular response to thapsigargin http://purl.obolibrary.org/obo/GO_1905892 GO:0085007 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from rhoptry OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085007 GO:0061044 biolink:BiologicalProcess negative regulation of vascular wound healing Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_0061044 GO:0085004 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from haustorium OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085004 GO:1905893 biolink:BiologicalProcess positive regulation of cellular response to thapsigargin Any process that activates or increases the frequency, rate or extent of cellular response to thapsigargin. go-plus.json up-regulation of cellular response to thapsigargin|upregulation of cellular response to thapsigargin|up regulation of cellular response to thapsigargin|activation of cellular response to thapsigargin http://purl.obolibrary.org/obo/GO_1905893 GO:0061045 biolink:BiologicalProcess negative regulation of wound healing Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. go-plus.json http://purl.obolibrary.org/obo/GO_0061045 GO:0085005 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from invasive hyphae OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085005 GO:1905894 biolink:BiologicalProcess regulation of cellular response to tunicamycin Any process that modulates the frequency, rate or extent of cellular response to tunicamycin. go-plus.json http://purl.obolibrary.org/obo/GO_1905894 GO:1905884 biolink:BiologicalProcess negative regulation of triglyceride transport Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport. go-plus.json inhibition of triacylglycerol transport|down regulation of triglyceride transport|inhibition of triglyceride transport|down regulation of triacylglycerol transport|downregulation of triacylglycerol transport|down-regulation of triglyceride transport|down-regulation of triacylglycerol transport|negative regulation of triacylglycerol transport|downregulation of triglyceride transport http://purl.obolibrary.org/obo/GO_1905884 GO:0085002 biolink:BiologicalProcess obsolete interaction with host mediated by secreted substance released by symbiont from symbiotic structure OBSOLETE. An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0085002 GO:0061046 biolink:BiologicalProcess regulation of branching involved in lung morphogenesis Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go-plus.json http://purl.obolibrary.org/obo/GO_0061046 GO:0085003 biolink:BiologicalProcess obsolete interaction with host via secreted substance released from stylet OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085003 GO:1905885 biolink:BiologicalProcess positive regulation of triglyceride transport Any process that activates or increases the frequency, rate or extent of triglyceride transport. go-plus.json up-regulation of triacylglycerol transport|upregulation of triglyceride transport|upregulation of triacylglycerol transport|up-regulation of triglyceride transport|activation of triglyceride transport|up regulation of triacylglycerol transport|activation of triacylglycerol transport|positive regulation of triacylglycerol transport|up regulation of triglyceride transport http://purl.obolibrary.org/obo/GO_1905885 GO:0061047 biolink:BiologicalProcess positive regulation of branching involved in lung morphogenesis Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go-plus.json http://purl.obolibrary.org/obo/GO_0061047 GO:1905886 biolink:BiologicalProcess obsolete chromatin remodeling involved in meiosis I OBSOLETE. Any chromatin remodeling that is involved in meiosis I. go-plus.json chromatin modeling involved in meiosis I|chromatin remodelling involved in meiosis I|meiosis-specific chromatin remodeling|chromatin modelling involved in meiosis I http://purl.obolibrary.org/obo/GO_1905886 GO:0061048 biolink:BiologicalProcess negative regulation of branching involved in lung morphogenesis Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go-plus.json http://purl.obolibrary.org/obo/GO_0061048 GO:0085000 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type V secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085000 GO:0061049 biolink:BiologicalProcess cell growth involved in cardiac muscle cell development The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go-plus.json cardiomyocyte growth|heart muscle cell growth|cardiac muscle cell hypertrophy http://purl.obolibrary.org/obo/GO_0061049 GO:1905887 biolink:BiologicalProcess autoinducer AI-2 transmembrane transport The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing. go-plus.json autoinducer 2 transmembrane transport|AI-2 transmembrane transport|(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport http://purl.obolibrary.org/obo/GO_1905887 GO:0085001 biolink:BiologicalProcess formation of stylet for nutrient acquisition The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation by symbiont of stylet for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0085001 GO:1905888 biolink:BiologicalProcess negative regulation of cellular response to very-low-density lipoprotein particle stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. go-plus.json down regulation of cellular response to very-low-density lipoprotein particle stimulus|down regulation of cellular response to VLDL particle stimulus|downregulation of cellular response to very-low-density lipoprotein particle stimulus|downregulation of cellular response to VLDL particle stimulus|down-regulation of cellular response to very-low-density lipoprotein particle stimulus|down-regulation of cellular response to VLDL particle stimulus|negative regulation of cellular response to VLDL particle stimulus|inhibition of cellular response to very-low-density lipoprotein particle stimulus|inhibition of cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_1905888 GO:1905889 biolink:BiologicalProcess positive regulation of cellular response to very-low-density lipoprotein particle stimulus Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. go-plus.json upregulation of cellular response to very-low-density lipoprotein particle stimulus|upregulation of cellular response to VLDL particle stimulus|up regulation of cellular response to very-low-density lipoprotein particle stimulus|up regulation of cellular response to VLDL particle stimulus|activation of cellular response to very-low-density lipoprotein particle stimulus|positive regulation of cellular response to VLDL particle stimulus|activation of cellular response to VLDL particle stimulus|up-regulation of cellular response to very-low-density lipoprotein particle stimulus|up-regulation of cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_1905889 NCBITaxon:4783 biolink:OrganismalEntity Phytophthora go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4783 GO:0002746 biolink:BiologicalProcess antigen processing and presentation following pinocytosis Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0002746 GO:0002747 biolink:BiologicalProcess antigen processing and presentation following phagocytosis Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0002747 GO:0002748 biolink:BiologicalProcess antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR). go-plus.json antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen|antigen processing and presentation initiated by PRR mediated uptake of antigen http://purl.obolibrary.org/obo/GO_0002748 CHEBI:51460 biolink:ChemicalSubstance albaflavenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51460 chebi_ph7_3 GO:0002749 biolink:BiologicalProcess antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR). go-plus.json antigen processing and presentation initiated by TLR mediated phagocytosis of antigen http://purl.obolibrary.org/obo/GO_0002749 GO:0002753 biolink:BiologicalProcess cytoplasmic pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go-plus.json cytoplasmic pathogen receptor signaling pathway|cytoplasmic PRR signaling pathway|cytoplasmic pattern recognition receptor signalling pathway|cytoplasmic PAMP receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002753 GO:0002754 biolink:BiologicalProcess intracellular endosomal pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go-plus.json intracellular vesicle PAMP receptor signaling pathway|intracellular vesicle pattern recognition receptor signaling pathway|intracellular vesicle pathogen receptor signaling pathway|intracellular vesicle PRR signaling pathway|intracellular vesicle pattern recognition receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002754 GO:0002755 biolink:BiologicalProcess MyD88-dependent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go-plus.json MyD88-dependent TLR signaling pathway|MyD88-dependent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002755 GO:0002756 biolink:BiologicalProcess MyD88-independent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go-plus.json MyD88-independent TLR signaling pathway|MyD88-independent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002756 GO:0002750 biolink:BiologicalProcess antigen processing and presentation following macropinocytosis Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0002750 GO:0002751 biolink:BiologicalProcess antigen processing and presentation following receptor mediated endocytosis Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0002751 GO:0002752 biolink:BiologicalProcess cell surface pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go-plus.json cell surface pathogen receptor signaling pathway|cell surface PRR signaling pathway|cell surface pattern recognition receptor signalling pathway|cell surface PAMP receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002752 CHEBI:51458 biolink:ChemicalSubstance (+)-epi-isozizaene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51458 chebi_ph7_3 GO:0061030 biolink:BiologicalProcess epithelial cell differentiation involved in mammary gland alveolus development The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. go-plus.json http://purl.obolibrary.org/obo/GO_0061030 GO:0061031 biolink:BiologicalProcess endodermal digestive tract morphogenesis The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0061031 GO:0061032 biolink:BiologicalProcess visceral serous pericardium development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. go-plus.json epicardium development http://purl.obolibrary.org/obo/GO_0061032 GO:0061033 biolink:BiologicalProcess secretion by lung epithelial cell involved in lung growth The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development. go-plus.json fetal lung liquid secretion http://purl.obolibrary.org/obo/GO_0061033 GO:0061034 biolink:BiologicalProcess olfactory bulb mitral cell layer development The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. go-plus.json http://purl.obolibrary.org/obo/GO_0061034 GO:1905895 biolink:BiologicalProcess negative regulation of cellular response to tunicamycin Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to tunicamycin. go-plus.json down-regulation of cellular response to tunicamycin|downregulation of cellular response to tunicamycin|down regulation of cellular response to tunicamycin|inhibition of cellular response to tunicamycin http://purl.obolibrary.org/obo/GO_1905895 GO:0061035 biolink:BiologicalProcess regulation of cartilage development Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0061035 GO:1905896 biolink:BiologicalProcess positive regulation of cellular response to tunicamycin Any process that activates or increases the frequency, rate or extent of cellular response to tunicamycin. go-plus.json up-regulation of cellular response to tunicamycin|activation of cellular response to tunicamycin|up regulation of cellular response to tunicamycin|upregulation of cellular response to tunicamycin http://purl.obolibrary.org/obo/GO_1905896 GO:0061036 biolink:BiologicalProcess positive regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0061036 GO:1905897 biolink:BiologicalProcess regulation of response to endoplasmic reticulum stress Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress. go-plus.json regulation of response to ER stress|regulation of cellular response to endoplasmic reticulum stress|regulation of ER stress response http://purl.obolibrary.org/obo/GO_1905897 GO:0061037 biolink:BiologicalProcess negative regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0061037 GO:0061038 biolink:BiologicalProcess uterus morphogenesis The process in which anatomical structures of the uterus are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061038 GO:1905898 biolink:BiologicalProcess positive regulation of response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress. go-plus.json up regulation of cellular response to endoplasmic reticulum stress|up regulation of response to ER stress|upregulation of ER stress response|activation of response to ER stress|activation of cellular response to endoplasmic reticulum stress|positive regulation of response to ER stress|positive regulation of cellular response to endoplasmic reticulum stress|up regulation of response to endoplasmic reticulum stress|activation of ER stress response|up-regulation of ER stress response|up-regulation of response to ER stress|up-regulation of cellular response to endoplasmic reticulum stress|upregulation of response to endoplasmic reticulum stress|positive regulation of ER stress response|upregulation of cellular response to endoplasmic reticulum stress|upregulation of response to ER stress|up regulation of ER stress response|activation of response to endoplasmic reticulum stress|up-regulation of response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_1905898 GO:1905899 biolink:BiologicalProcess regulation of smooth muscle tissue development Any process that modulates the frequency, rate or extent of smooth muscle tissue development. go-plus.json http://purl.obolibrary.org/obo/GO_1905899 GO:0061039 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061039 CHEBI:145715 biolink:ChemicalSubstance hex-3-en-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_145715 chebi_ph7_3 CHEBI:51453 biolink:ChemicalSubstance (S)-carnitinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_51453 CHEBI:51454 biolink:ChemicalSubstance cyclopropanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_51454 GO:0002757 biolink:BiologicalProcess immune response-activating signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002757 GO:0002758 biolink:BiologicalProcess innate immune response-activating signal transduction A series of molecular signals generated as a consequence of a pathogen or microbial effector binding to a plant 'resistance-gene' receptor to activate a plant immune response, usually plant-type hypersensitive response. go-plus.json defense response signalling pathway, resistance gene-dependent|defense response signaling pathway, resistance gene-independent|effector-triggered immunity|defence response signaling pathway, resistance gene-dependent|defence response signalling pathway, resistance gene-dependent|defence response signaling pathway, resistance gene-independent|effector-triggered immune signaling|defence response signalling pathway, resistance gene-independent|effector triggered immunity|defense response signaling pathway, resistance gene-dependent http://purl.obolibrary.org/obo/GO_0002758 GO:0002759 biolink:BiologicalProcess regulation of antimicrobial humoral response Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response. go-plus.json http://purl.obolibrary.org/obo/GO_0002759 GO:0099632 biolink:BiologicalProcess protein transport within plasma membrane A process in which protein is transported from one region of the plasma membrane to another. go-plus.json http://purl.obolibrary.org/obo/GO_0099632 GO:0002720 biolink:BiologicalProcess positive regulation of cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. go-plus.json up regulation of cytokine production during immune response|positive regulation of cytokine secretion involved in immune response|positive regulation of cytokine production during immune response|upregulation of cytokine production during immune response|stimulation of cytokine production during immune response|activation of cytokine production during immune response|positive regulation of cytokine biosynthetic process involved in immune response|up-regulation of cytokine production during immune response http://purl.obolibrary.org/obo/GO_0002720 GO:0099633 biolink:BiologicalProcess protein localization to postsynaptic specialization membrane A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density). go-plus.json protein localisation in postsynaptic specialization membrane http://purl.obolibrary.org/obo/GO_0099633 GO:0002721 biolink:BiologicalProcess regulation of B cell cytokine production Any process that modulates the frequency, rate, or extent of B cell cytokine production. go-plus.json regulation of B-cell cytokine production|regulation of B-lymphocyte cytokine production|regulation of B lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002721 GO:0099630 biolink:BiologicalProcess postsynaptic neurotransmitter receptor cycle The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099630 GO:0002722 biolink:BiologicalProcess negative regulation of B cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production. go-plus.json negative regulation of B-cell cytokine production|negative regulation of B-lymphocyte cytokine production|down-regulation of B cell cytokine production|negative regulation of B lymphocyte cytokine production|downregulation of B cell cytokine production|down regulation of B cell cytokine production|inhibition of B cell cytokine production http://purl.obolibrary.org/obo/GO_0002722 GO:0002723 biolink:BiologicalProcess positive regulation of B cell cytokine production Any process that activates or increases the frequency, rate, or extent of B cell cytokine production. go-plus.json upregulation of B cell cytokine production|stimulation of B cell cytokine production|positive regulation of B-cell cytokine production|activation of B cell cytokine production|up-regulation of B cell cytokine production|positive regulation of B-lymphocyte cytokine production|up regulation of B cell cytokine production|positive regulation of B lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002723 GO:0099631 biolink:CellularComponent postsynaptic endocytic zone cytoplasmic component The cytoplasmic component of the postsynaptic endocytic zone. go-plus.json postsynaptic endocytic zone cytoplasmic component http://purl.obolibrary.org/obo/GO_0099631 goslim_synapse NCBITaxon:4751 biolink:OrganismalEntity Fungi go-plus.json Mycota|fungi http://purl.obolibrary.org/obo/NCBITaxon_4751 CHEBI:51446 biolink:ChemicalSubstance organic divalent group go-plus.json http://purl.obolibrary.org/obo/CHEBI_51446 CHEBI:51447 biolink:ChemicalSubstance organic univalent group go-plus.json http://purl.obolibrary.org/obo/CHEBI_51447 GO:0061060 biolink:BiologicalProcess negative regulation of peptidoglycan recognition protein signaling pathway Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. go-plus.json negative regulation of peptidoglycan recognition protein signalling pathway http://purl.obolibrary.org/obo/GO_0061060 GO:0061061 biolink:BiologicalProcess muscle structure development The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0061061 goslim_drosophila GO:0061062 biolink:BiologicalProcess regulation of nematode larval development Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go-plus.json http://purl.obolibrary.org/obo/GO_0061062 GO:0061063 biolink:BiologicalProcess positive regulation of nematode larval development Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go-plus.json http://purl.obolibrary.org/obo/GO_0061063 GO:0085028 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0085028 GO:0061064 biolink:BiologicalProcess negative regulation of nematode larval development Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go-plus.json http://purl.obolibrary.org/obo/GO_0061064 GO:0061065 biolink:BiologicalProcess regulation of dauer larval development Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go-plus.json http://purl.obolibrary.org/obo/GO_0061065 CHEBI:26481 biolink:ChemicalSubstance quercetin bissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26481 GO:0085029 biolink:BiologicalProcess extracellular matrix assembly The aggregation, arrangement and bonding together of the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0085029 GO:0085026 biolink:CellularComponent tubovesicular membrane network A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains. go-plus.json TVN|TVM network http://purl.obolibrary.org/obo/GO_0085026 GO:0061066 biolink:BiologicalProcess positive regulation of dauer larval development Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go-plus.json http://purl.obolibrary.org/obo/GO_0061066 CHEBI:26482 biolink:ChemicalSubstance quercetin sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26482 GO:0061067 biolink:BiologicalProcess negative regulation of dauer larval development Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go-plus.json http://purl.obolibrary.org/obo/GO_0061067 GO:0085027 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0085027 CHEBI:26483 biolink:ChemicalSubstance quercetin trissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26483 GO:0061068 biolink:BiologicalProcess urethra development The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. go-plus.json http://purl.obolibrary.org/obo/GO_0061068 GO:0085024 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by Sec complex OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification by symbiont of host morphology or physiology via protein secreted by the Sec secretion system http://purl.obolibrary.org/obo/GO_0085024 GO:0085025 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by Tat complex OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification by symbiont of host morphology or physiology via protein secreted by the Tat secretion system http://purl.obolibrary.org/obo/GO_0085025 GO:0061069 biolink:BiologicalProcess male urethra development The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. go-plus.json http://purl.obolibrary.org/obo/GO_0061069 GO:0085022 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085022 GO:0085023 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085023 CHEBI:26490 biolink:ChemicalSubstance quinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26490 GO:0085020 biolink:BiologicalProcess protein K6-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair. go-plus.json protein K6-linked polyubiquitination http://purl.obolibrary.org/obo/GO_0085020 GO:0085021 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type I secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085021 CHEBI:51440 biolink:ChemicalSubstance L-isoascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51440 GO:0002728 biolink:BiologicalProcess negative regulation of natural killer cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production. go-plus.json down regulation of natural killer cell cytokine production|downregulation of natural killer cell cytokine production|negative regulation of NK cell cytokine production|down-regulation of natural killer cell cytokine production|inhibition of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002728 NCBITaxon:4761 biolink:OrganismalEntity Chytridiomycota go-plus.json Mastigomycotina|Monoblepharidomycota|chytrids http://purl.obolibrary.org/obo/NCBITaxon_4761 GO:0002729 biolink:BiologicalProcess positive regulation of natural killer cell cytokine production Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production. go-plus.json positive regulation of NK cell cytokine production|up regulation of natural killer cell cytokine production|activation of natural killer cell cytokine production|stimulation of natural killer cell cytokine production|up-regulation of natural killer cell cytokine production|upregulation of natural killer cell cytokine production http://purl.obolibrary.org/obo/GO_0002729 GO:0099638 biolink:BiologicalProcess endosome to plasma membrane protein transport The directed movement of proteins from the endosome to the plasma membrane in transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0099638 GO:0099639 biolink:BiologicalProcess neurotransmitter receptor transport, endosome to plasma membrane The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0099639 goslim_synapse GO:0002724 biolink:BiologicalProcess regulation of T cell cytokine production Any process that modulates the frequency, rate, or extent of T cell cytokine production. go-plus.json regulation of T-cell cytokine production|regulation of T-lymphocyte cytokine production|regulation of T lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002724 GO:0099636 biolink:BiologicalProcess cytoplasmic streaming The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains. Wikipedia:Cytoplasmic_streaming go-plus.json http://purl.obolibrary.org/obo/GO_0099636 CHEBI:145707 biolink:ChemicalSubstance glycosylarabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_145707 GO:0099637 biolink:BiologicalProcess neurotransmitter receptor transport The directed movement of neurotransmitter receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0099637 goslim_synapse GO:0002725 biolink:BiologicalProcess negative regulation of T cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. go-plus.json down-regulation of T cell cytokine production|negative regulation of T lymphocyte cytokine production|downregulation of T cell cytokine production|down regulation of T cell cytokine production|inhibition of T cell cytokine production|negative regulation of T-cell cytokine production|negative regulation of T-lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002725 GO:0099634 biolink:CellularComponent postsynaptic specialization membrane The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. go-plus.json http://purl.obolibrary.org/obo/GO_0099634 goslim_synapse GO:0002726 biolink:BiologicalProcess positive regulation of T cell cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production. go-plus.json up regulation of T cell cytokine production|positive regulation of T lymphocyte cytokine production|upregulation of T cell cytokine production|stimulation of T cell cytokine production|positive regulation of T-cell cytokine production|up-regulation of T cell cytokine production|activation of T cell cytokine production|positive regulation of T-lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002726 GO:0099635 biolink:MolecularActivity voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0099635 goslim_synapse GO:0002727 biolink:BiologicalProcess regulation of natural killer cell cytokine production Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production. go-plus.json regulation of NK cell cytokine production http://purl.obolibrary.org/obo/GO_0002727 GO:0002731 biolink:BiologicalProcess negative regulation of dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production. go-plus.json downregulation of dendritic cell cytokine production|down regulation of dendritic cell cytokine production|inhibition of dendritic cell cytokine production|down-regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002731 GO:0099643 biolink:BiologicalProcess signal release from synapse Any signal release from a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099643 goslim_synapse GO:0002732 biolink:BiologicalProcess positive regulation of dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production. go-plus.json up regulation of dendritic cell cytokine production|upregulation of dendritic cell cytokine production|stimulation of dendritic cell cytokine production|up-regulation of dendritic cell cytokine production|activation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002732 GO:0099644 biolink:BiologicalProcess protein localization to presynaptic membrane A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane. go-plus.json protein localization in presynaptic membrane|protein localisation to presynaptic membrane|protein localisation in presynaptic membrane http://purl.obolibrary.org/obo/GO_0099644 GO:0002733 biolink:BiologicalProcess regulation of myeloid dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production. go-plus.json http://purl.obolibrary.org/obo/GO_0002733 GO:0099641 biolink:BiologicalProcess anterograde axonal protein transport The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. go-plus.json anterograde axon cargo transport http://purl.obolibrary.org/obo/GO_0099641 goslim_synapse GO:0002734 biolink:BiologicalProcess negative regulation of myeloid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production. go-plus.json down regulation of myeloid dendritic cell cytokine production|inhibition of myeloid dendritic cell cytokine production|down-regulation of myeloid dendritic cell cytokine production|downregulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002734 GO:0099642 biolink:BiologicalProcess retrograde axonal protein transport The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. go-plus.json retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_0099642 goslim_synapse GO:0099640 biolink:BiologicalProcess axo-dendritic protein transport The directed movement of proteins along microtubules in neuron projections. go-plus.json axonal protein transport http://purl.obolibrary.org/obo/GO_0099640 goslim_synapse NCBITaxon:4762 biolink:OrganismalEntity Oomycota go-plus.json Peronosporomycetes|oomycetes|Oomycetes http://purl.obolibrary.org/obo/NCBITaxon_4762 GO:0002730 biolink:BiologicalProcess regulation of dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production. go-plus.json http://purl.obolibrary.org/obo/GO_0002730 GO:0061050 biolink:BiologicalProcess regulation of cell growth involved in cardiac muscle cell development Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061050 GO:0085019 biolink:BiologicalProcess formation of tubovesicular network for nutrient acquisition The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation of a symbiont- induced tubovesicular network for nutrient acquisition from host|formation by symbiont of a tubovesicular network for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0085019 GO:0061051 biolink:BiologicalProcess positive regulation of cell growth involved in cardiac muscle cell development Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061051 GO:0061052 biolink:BiologicalProcess negative regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061052 GO:0085017 biolink:BiologicalProcess entry into host cell by a symbiont-containing vacuole The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole. go-plus.json symbiont entry into host cell forming a pathogen-containing vacuole|symbiont entry into host cell forming a symbiont-containing vacuole|symbiont entry into host cell forming a parasitophorous vacuole http://purl.obolibrary.org/obo/GO_0085017 GO:0061053 biolink:BiologicalProcess somite development The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0061053 GO:0085018 biolink:BiologicalProcess obsolete maintenance of symbiont-containing vacuole by host OBSOLETE. The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment. go-plus.json maintenance of vacuolar integrity during bacterial infection|maintenance of parasitophorous vacuole|maintenance of pathogen-containing vacuole http://purl.obolibrary.org/obo/GO_0085018 GO:0061054 biolink:BiologicalProcess dermatome development The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go-plus.json http://purl.obolibrary.org/obo/GO_0061054 GO:0085015 biolink:BiologicalProcess dormancy maintenance of symbiont in host Any process in which a dormant state is maintained by the symbiont within the host organism. go-plus.json NRP|non-replicating persistence http://purl.obolibrary.org/obo/GO_0085015 GO:0061055 biolink:BiologicalProcess myotome development The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0061055 CHEBI:26493 biolink:ChemicalSubstance quinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26493 GO:0085016 biolink:BiologicalProcess dormancy exit of symbiont in host Exit from dormant state, also known as resuscitation, of the symbiont within the host organism. go-plus.json resuscitation of symbiont http://purl.obolibrary.org/obo/GO_0085016 GO:0061056 biolink:BiologicalProcess sclerotome development The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. go-plus.json http://purl.obolibrary.org/obo/GO_0061056 GO:0061057 biolink:BiologicalProcess peptidoglycan recognition protein signaling pathway A series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides. go-plus.json Imd signalling pathway|immune deficiency signaling pathway|Imd signaling pathway|PGRP signaling pathway|immune deficiency pathway http://purl.obolibrary.org/obo/GO_0061057 GO:0085013 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type VII secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085013 GO:0085014 biolink:BiologicalProcess dormancy entry of symbiont in host Entry into a dormant state of the symbiont within the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0085014 GO:0061058 biolink:BiologicalProcess regulation of peptidoglycan recognition protein signaling pathway Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. go-plus.json regulation of peptidoglycan recognition protein signalling pathway http://purl.obolibrary.org/obo/GO_0061058 GO:0085011 biolink:BiologicalProcess obsolete interaction with host via protein secreted by Sec complex OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host via protein secreted by Sec secretion system http://purl.obolibrary.org/obo/GO_0085011 GO:0061059 biolink:BiologicalProcess positive regulation of peptidoglycan recognition protein signaling pathway Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. go-plus.json positive regulation of peptidoglycan recognition protein signalling pathway http://purl.obolibrary.org/obo/GO_0061059 GO:0085012 biolink:BiologicalProcess obsolete interaction with host via protein secreted by Tat complex OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host via protein secreted by Tat secretion system http://purl.obolibrary.org/obo/GO_0085012 GO:0085010 biolink:BiologicalProcess obsolete interaction with host mediated by secreted substance entering host via endocytosis OBSOLETE. An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0085010 CHEBI:9638 biolink:ChemicalSubstance torulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_9638 chebi_ph7_3 GO:0002739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002739 GO:0002735 biolink:BiologicalProcess positive regulation of myeloid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production. go-plus.json upregulation of myeloid dendritic cell cytokine production|stimulation of myeloid dendritic cell cytokine production|activation of myeloid dendritic cell cytokine production|up-regulation of myeloid dendritic cell cytokine production|up regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002735 GO:0002736 biolink:BiologicalProcess regulation of plasmacytoid dendritic cell cytokine production Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. go-plus.json http://purl.obolibrary.org/obo/GO_0002736 GO:0002737 biolink:BiologicalProcess negative regulation of plasmacytoid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. go-plus.json downregulation of plasmacytoid dendritic cell cytokine production|down-regulation of plasmacytoid dendritic cell cytokine production|inhibition of plasmacytoid dendritic cell cytokine production|down regulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002737 GO:0099645 biolink:BiologicalProcess neurotransmitter receptor localization to postsynaptic specialization membrane A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density). go-plus.json neurotransmitter receptor localisation in postsynaptic specialization membrane http://purl.obolibrary.org/obo/GO_0099645 goslim_synapse GO:0002738 biolink:BiologicalProcess positive regulation of plasmacytoid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. go-plus.json up regulation of plasmacytoid dendritic cell cytokine production|activation of plasmacytoid dendritic cell cytokine production|stimulation of plasmacytoid dendritic cell cytokine production|up-regulation of plasmacytoid dendritic cell cytokine production|upregulation of plasmacytoid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002738 GO:0099646 biolink:BiologicalProcess neurotransmitter receptor transport, plasma membrane to endosome Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0099646 goslim_synapse GO:0099699 biolink:CellularComponent integral component of synaptic membrane The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099699 goslim_synapse GO:0002700 biolink:BiologicalProcess regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002700 GO:0002701 biolink:BiologicalProcess negative regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. go-plus.json down regulation of production of molecular mediator of immune response|downregulation of production of molecular mediator of immune response|down-regulation of production of molecular mediator of immune response|inhibition of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002701 CHEBI:51422 biolink:ChemicalSubstance organodiyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_51422 GO:0061080 biolink:BiologicalProcess right horn of sinus venosus development The progression of the right horn of the sinus venosus from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061080 GO:0061081 biolink:BiologicalProcess positive regulation of myeloid leukocyte cytokine production involved in immune response Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. go-plus.json positive regulation of myeloid cell cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0061081 CHEBI:26469 biolink:ChemicalSubstance quaternary nitrogen compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_26469 GO:0061082 biolink:BiologicalProcess myeloid leukocyte cytokine production Any process that contributes to cytokine production by a myeloid cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061082 gocheck_do_not_annotate CHEBI:26463 biolink:ChemicalSubstance pyruvate family amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26463 GO:0061083 biolink:BiologicalProcess regulation of protein refolding Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. go-plus.json http://purl.obolibrary.org/obo/GO_0061083 GO:0061084 biolink:BiologicalProcess negative regulation of protein refolding Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. go-plus.json http://purl.obolibrary.org/obo/GO_0061084 GO:0061085 biolink:BiologicalProcess regulation of histone H3-K27 methylation Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0061085 GO:0061086 biolink:BiologicalProcess negative regulation of histone H3-K27 methylation Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0061086 GO:0061087 biolink:BiologicalProcess positive regulation of histone H3-K27 methylation Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0061087 GO:0061088 biolink:BiologicalProcess regulation of sequestering of zinc ion Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. go-plus.json http://purl.obolibrary.org/obo/GO_0061088 GO:0061089 biolink:BiologicalProcess negative regulation of sequestering of zinc ion Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. go-plus.json http://purl.obolibrary.org/obo/GO_0061089 CHEBI:26461 biolink:ChemicalSubstance pyrroloquinoline cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_26461 GO:0085044 biolink:BiologicalProcess disassembly by symbiont of host cuticle The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json degradation of host cuticle|catabolism of host cuticle http://purl.obolibrary.org/obo/GO_0085044 GO:0085042 biolink:CellularComponent periarbuscular membrane A host-derived membrane surrounding the symbiont arbuscule during symbiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0085042 GO:0085040 biolink:CellularComponent obsolete extra-invasive hyphal space OBSOLETE. The space between the symbiont plasma membrane and the extra-invasive hyphal membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0085040 GO:0085041 biolink:CellularComponent arbuscule Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0085041 GO:0002706 biolink:BiologicalProcess regulation of lymphocyte mediated immunity Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. go-plus.json http://purl.obolibrary.org/obo/GO_0002706 CHEBI:9688 biolink:ChemicalSubstance trichodermin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9688 chebi_ph7_3 GO:0002707 biolink:BiologicalProcess negative regulation of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. go-plus.json down-regulation of lymphocyte mediated immunity|downregulation of lymphocyte mediated immunity|down regulation of lymphocyte mediated immunity|inhibition of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002707 GO:0002708 biolink:BiologicalProcess positive regulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. go-plus.json stimulation of lymphocyte mediated immunity|up-regulation of lymphocyte mediated immunity|activation of lymphocyte mediated immunity|up regulation of lymphocyte mediated immunity|upregulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002708 GO:0002709 biolink:BiologicalProcess regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell mediated immunity. go-plus.json regulation of T-lymphocyte mediated immunity|regulation of T lymphocyte mediated immunity|regulation of T-cell mediated immunity http://purl.obolibrary.org/obo/GO_0002709 GO:0002702 biolink:BiologicalProcess positive regulation of production of molecular mediator of immune response Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. go-plus.json upregulation of production of molecular mediator of immune response|up regulation of production of molecular mediator of immune response|activation of production of molecular mediator of immune response|stimulation of production of molecular mediator of immune response|up-regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002702 GO:0002703 biolink:BiologicalProcess regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. go-plus.json regulation of leucocyte mediated immunity|regulation of immune cell mediated immunity http://purl.obolibrary.org/obo/GO_0002703 GO:0002704 biolink:BiologicalProcess negative regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. go-plus.json down-regulation of leukocyte mediated immunity|inhibition of leukocyte mediated immunity|negative regulation of immune cell mediated immunity|down regulation of leukocyte mediated immunity|downregulation of leukocyte mediated immunity|negative regulation of leucocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002704 GO:0002705 biolink:BiologicalProcess positive regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. go-plus.json positive regulation of immune cell mediated immunity|up-regulation of leukocyte mediated immunity|upregulation of leukocyte mediated immunity|positive regulation of leucocyte mediated immunity|up regulation of leukocyte mediated immunity|activation of leukocyte mediated immunity|stimulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002705 GO:0002710 biolink:BiologicalProcess negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. go-plus.json negative regulation of T-lymphocyte mediated immunity|down-regulation of T cell mediated immunity|negative regulation of T lymphocyte mediated immunity|downregulation of T cell mediated immunity|down regulation of T cell mediated immunity|inhibition of T cell mediated immunity|negative regulation of T-cell mediated immunity http://purl.obolibrary.org/obo/GO_0002710 GO:0002711 biolink:BiologicalProcess positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. go-plus.json stimulation of T cell mediated immunity|positive regulation of T-cell mediated immunity|up-regulation of T cell mediated immunity|activation of T cell mediated immunity|positive regulation of T-lymphocyte mediated immunity|up regulation of T cell mediated immunity|positive regulation of T lymphocyte mediated immunity|upregulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002711 GO:0002712 biolink:BiologicalProcess regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of B cell mediated immunity. go-plus.json regulation of B lymphocyte mediated immunity|regulation of B-cell mediated immunity|regulation of B-lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002712 GO:0061070 biolink:BiologicalProcess female urethra development The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. go-plus.json http://purl.obolibrary.org/obo/GO_0061070 GO:0061071 biolink:BiologicalProcess urethra epithelium development The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. go-plus.json http://purl.obolibrary.org/obo/GO_0061071 GO:0061072 biolink:BiologicalProcess iris morphogenesis The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. go-plus.json http://purl.obolibrary.org/obo/GO_0061072 GO:0061073 biolink:BiologicalProcess ciliary body morphogenesis The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. go-plus.json http://purl.obolibrary.org/obo/GO_0061073 GO:0061074 biolink:BiologicalProcess regulation of neural retina development Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061074 GO:0085039 biolink:CellularComponent hyphal membrane A host-derived membrane surrounding the symbiont hypha during infection. go-plus.json extra-invasive hyphal membrane http://purl.obolibrary.org/obo/GO_0085039 GO:0061075 biolink:BiologicalProcess positive regulation of neural retina development Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061075 GO:0061076 biolink:BiologicalProcess negative regulation of neural retina development Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061076 GO:0061077 biolink:BiologicalProcess chaperone-mediated protein folding The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. go-plus.json http://purl.obolibrary.org/obo/GO_0061077 GO:0085037 biolink:CellularComponent extrahaustorial membrane The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0085037 GO:0061078 biolink:BiologicalProcess positive regulation of prostaglandin secretion involved in immune response Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response. go-plus.json positive regulation of prostaglandin secretion during immune response http://purl.obolibrary.org/obo/GO_0061078 GO:0085035 biolink:CellularComponent haustorium A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0085035 GO:0061079 biolink:BiologicalProcess left horn of sinus venosus development The progression of the left horn of the sinus venosus from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061079 GO:0085036 biolink:CellularComponent extrahaustorial matrix The space between the symbiont plasma membrane and the extrahaustorial membrane of the host. go-plus.json http://purl.obolibrary.org/obo/GO_0085036 GO:0085033 biolink:BiologicalProcess induction by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|stimulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|activation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of nuclear factor kappa-light-chain-enhancer of activated B cells mediated signal transduction pathway|up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|upregulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host NF-kappaB-mediated signal transduction pathway|induction by symbiont of host I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0085033 GO:0085034 biolink:BiologicalProcess suppression by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0085034 GO:0085031 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0085031 GO:0085032 biolink:BiologicalProcess modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host NF-kappaB-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0085032 GO:0085030 biolink:BiologicalProcess symbiotic process benefiting host A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. go-plus.json mutualism http://purl.obolibrary.org/obo/GO_0085030 GO:0002717 biolink:BiologicalProcess positive regulation of natural killer cell mediated immunity Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity. go-plus.json upregulation of natural killer cell mediated immunity|positive regulation of NK cell mediated immunity|up regulation of natural killer cell mediated immunity|positive regulation of natural killer cell activity|activation of natural killer cell mediated immunity|stimulation of natural killer cell mediated immunity|positive regulation of NK cell activity|up-regulation of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0002717 GO:0002718 biolink:BiologicalProcess regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. go-plus.json regulation of cytokine biosynthetic process involved in immune response|regulation of cytokine secretion involved in immune response|regulation of cytokine production during immune response http://purl.obolibrary.org/obo/GO_0002718 GO:0002719 biolink:BiologicalProcess negative regulation of cytokine production involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. go-plus.json inhibition of cytokine production during immune response|down-regulation of cytokine production during immune response|negative regulation of cytokine biosynthetic process involved in immune response|negative regulation of cytokine secretion involved in immune response|downregulation of cytokine production during immune response|negative regulation of cytokine production during immune response|down regulation of cytokine production during immune response http://purl.obolibrary.org/obo/GO_0002719 GO:0002713 biolink:BiologicalProcess negative regulation of B cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. go-plus.json downregulation of B cell mediated immunity|down regulation of B cell mediated immunity|inhibition of B cell mediated immunity|negative regulation of B-cell mediated immunity|negative regulation of B-lymphocyte mediated immunity|down-regulation of B cell mediated immunity|negative regulation of B lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002713 GO:0002714 biolink:BiologicalProcess positive regulation of B cell mediated immunity Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. go-plus.json positive regulation of B lymphocyte mediated immunity|upregulation of B cell mediated immunity|positive regulation of B-cell mediated immunity|stimulation of B cell mediated immunity|up-regulation of B cell mediated immunity|activation of B cell mediated immunity|positive regulation of B-lymphocyte mediated immunity|up regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002714 GO:0002715 biolink:BiologicalProcess regulation of natural killer cell mediated immunity Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity. go-plus.json regulation of NK cell mediated immunity|regulation of natural killer cell activity http://purl.obolibrary.org/obo/GO_0002715 GO:0002716 biolink:BiologicalProcess negative regulation of natural killer cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. go-plus.json down regulation of natural killer cell mediated immunity|negative regulation of natural killer cell activity|downregulation of natural killer cell mediated immunity|negative regulation of NK cell mediated immunity|negative regulation of NK cell activity|down-regulation of natural killer cell mediated immunity|inhibition of natural killer cell mediated immunity http://purl.obolibrary.org/obo/GO_0002716 CHEBI:26444 biolink:ChemicalSubstance pyrimidine ribonucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26444 CHEBI:26446 biolink:ChemicalSubstance pyrimidine ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26446 CHEBI:26447 biolink:ChemicalSubstance pyrimidinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26447 CHEBI:26440 biolink:ChemicalSubstance pyrimidine nucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_26440 CHEBI:26441 biolink:ChemicalSubstance pyrimidine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26441 CHEBI:26442 biolink:ChemicalSubstance pyrimidine ribonucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26442 CHEBI:26443 biolink:ChemicalSubstance pyrimidine ribonucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26443 UBERON:0008000 biolink:AnatomicalEntity sesamoid bone of pes A sesamoid bone that is part of a pes. go-plus.json sesamoid bone of foot http://purl.obolibrary.org/obo/UBERON_0008000 UBERON:0008001 biolink:AnatomicalEntity irregular bone The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid. go-plus.json os irregulare|os irregulare http://purl.obolibrary.org/obo/UBERON_0008001 CHEBI:9661 biolink:ChemicalSubstance triacetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9661 chebi_ph7_3 CHEBI:26455 biolink:ChemicalSubstance pyrroles go-plus.json http://purl.obolibrary.org/obo/CHEBI_26455 GO:0061090 biolink:BiologicalProcess positive regulation of sequestering of zinc ion Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. go-plus.json http://purl.obolibrary.org/obo/GO_0061090 CHEBI:26456 biolink:ChemicalSubstance pyrrolidine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26456 GO:0061091 biolink:BiologicalProcess regulation of phospholipid translocation Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go-plus.json http://purl.obolibrary.org/obo/GO_0061091 CHEBI:26457 biolink:ChemicalSubstance 1-pyrrolinecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26457 GO:0061092 biolink:BiologicalProcess positive regulation of phospholipid translocation Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go-plus.json http://purl.obolibrary.org/obo/GO_0061092 GO:0061093 biolink:BiologicalProcess negative regulation of phospholipid translocation Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go-plus.json http://purl.obolibrary.org/obo/GO_0061093 GO:0061094 biolink:BiologicalProcess regulation of turning behavior involved in mating Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go-plus.json http://purl.obolibrary.org/obo/GO_0061094 CHEBI:26452 biolink:ChemicalSubstance pyrrolecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26452 GO:0061095 biolink:BiologicalProcess positive regulation of turning behavior involved in mating Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go-plus.json http://purl.obolibrary.org/obo/GO_0061095 CHEBI:26454 biolink:ChemicalSubstance pyrrolecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26454 GO:0061096 biolink:BiologicalProcess negative regulation of turning behavior involved in mating Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go-plus.json http://purl.obolibrary.org/obo/GO_0061096 GO:0061097 biolink:BiologicalProcess regulation of protein tyrosine kinase activity Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061097 GO:0061098 biolink:BiologicalProcess positive regulation of protein tyrosine kinase activity Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061098 GO:0061099 biolink:BiologicalProcess negative regulation of protein tyrosine kinase activity Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061099 GO:0051632 biolink:BiologicalProcess negative regulation of acetylcholine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. go-plus.json down regulation of acetylcholine uptake|negative regulation of acetylcholine import|down-regulation of acetylcholine uptake|downregulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051632 GO:0051633 biolink:BiologicalProcess positive regulation of acetylcholine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell. go-plus.json upregulation of acetylcholine uptake|positive regulation of acetylcholine import|stimulation of acetylcholine uptake|activation of acetylcholine uptake|up-regulation of acetylcholine uptake|up regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051633 GO:0051630 biolink:BiologicalProcess acetylcholine uptake The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. go-plus.json acetylcholine import http://purl.obolibrary.org/obo/GO_0051630 GO:0075601 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075601 GO:0051631 biolink:BiologicalProcess regulation of acetylcholine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. go-plus.json regulation of acetylcholine import http://purl.obolibrary.org/obo/GO_0051631 GO:0051636 biolink:MolecularActivity obsolete Gram-negative bacterial cell surface binding OBSOLETE. Binding to a component on the surface of a Gram-negative bacterial cell. go-plus.json Gram-negative bacterium binding|Gram-negative bacterial cell surface binding|Gram-negative bacterial binding|Gram-negative bacterium cell surface binding|binding to Gram-negative bacterium http://purl.obolibrary.org/obo/GO_0051636 GO:0051637 biolink:MolecularActivity obsolete Gram-positive bacterial cell surface binding OBSOLETE. Binding to a component on the surface of a Gram-positive bacterium. go-plus.json Gram-positive bacterium binding|Gram-positive bacterial cell surface binding|Gram-positive bacterial binding|binding to Gram-positive bacterium|Gram-positive bacterium cell surface binding http://purl.obolibrary.org/obo/GO_0051637 GO:0051634 biolink:BiologicalProcess inhibition of acetylcholine uptake Any process that prevents the activation of the directed movement of acetylcholine into a cell. go-plus.json inhibition of acetylcholine import http://purl.obolibrary.org/obo/GO_0051634 GO:0051635 biolink:MolecularActivity obsolete bacterial cell surface binding OBSOLETE. Binding to a component on the surface of a bacterial cell. go-plus.json binding to bacterium|bacterium cell surface binding|bacterium binding|bacterial cell surface binding|bacterial binding http://purl.obolibrary.org/obo/GO_0051635 GO:0075606 biolink:BiologicalProcess transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane. VZ:990 go-plus.json cytoplasmic inwards viral transport|viral genome transport to host cell nucleus|transport of viral material to nucleus http://purl.obolibrary.org/obo/GO_0075606 GO:0051638 biolink:BiologicalProcess barbed-end actin filament uncapping The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. go-plus.json barbed-end F-actin uncapping|plus end actin filament uncapping|plus end F-actin uncapping|barbed end F-actin uncapping|plus-end F-actin uncapping|plus-end actin filament uncapping|barbed end actin filament uncapping http://purl.obolibrary.org/obo/GO_0051638 GO:0051639 biolink:BiologicalProcess actin filament network formation The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments. go-plus.json actin gel formation|actin gel biosynthesis http://purl.obolibrary.org/obo/GO_0051639 GO:1905800 biolink:BiologicalProcess negative regulation of intraciliary retrograde transport Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport. go-plus.json down regulation of intraciliary retrograde transport|downregulation of intraciliary retrograde transport|down regulation of intraflagellar retrograde transport|downregulation of intraflagellar retrograde transport|down-regulation of intraciliary retrograde transport|down-regulation of intraflagellar retrograde transport|negative regulation of intraflagellar retrograde transport|inhibition of intraciliary retrograde transport|inhibition of intraflagellar retrograde transport http://purl.obolibrary.org/obo/GO_1905800 GO:1905801 biolink:BiologicalProcess positive regulation of intraciliary retrograde transport Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport. go-plus.json upregulation of intraciliary retrograde transport|upregulation of intraflagellar retrograde transport|up regulation of intraciliary retrograde transport|activation of intraciliary retrograde transport|up regulation of intraflagellar retrograde transport|activation of intraflagellar retrograde transport|positive regulation of intraflagellar retrograde transport|up-regulation of intraciliary retrograde transport|up-regulation of intraflagellar retrograde transport http://purl.obolibrary.org/obo/GO_1905801 GO:1905802 biolink:BiologicalProcess regulation of cellular response to manganese ion Any process that modulates the frequency, rate or extent of cellular response to manganese ion. go-plus.json regulation of cellular response to manganese http://purl.obolibrary.org/obo/GO_1905802 GO:1905803 biolink:BiologicalProcess negative regulation of cellular response to manganese ion Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion. go-plus.json down-regulation of cellular response to manganese ion|down-regulation of cellular response to manganese|negative regulation of cellular response to manganese|downregulation of cellular response to manganese ion|down regulation of cellular response to manganese ion|inhibition of cellular response to manganese ion|downregulation of cellular response to manganese|down regulation of cellular response to manganese|inhibition of cellular response to manganese http://purl.obolibrary.org/obo/GO_1905803 GO:1905804 biolink:BiologicalProcess positive regulation of cellular response to manganese ion Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion. go-plus.json up-regulation of cellular response to manganese ion|activation of cellular response to manganese ion|up-regulation of cellular response to manganese|activation of cellular response to manganese|up regulation of cellular response to manganese ion|positive regulation of cellular response to manganese|up regulation of cellular response to manganese|upregulation of cellular response to manganese ion|upregulation of cellular response to manganese http://purl.obolibrary.org/obo/GO_1905804 GO:1905805 biolink:BiologicalProcess excitatory synapse pruning The disaggregation of an excitatory synapse into its constituent components. go-plus.json synapse clearance|synapse disassembly|synapse removal|synapse elimination http://purl.obolibrary.org/obo/GO_1905805 CHEBI:75397 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_75397 chebi_ph7_3 GO:1905806 biolink:BiologicalProcess regulation of synapse pruning Any process that modulates the frequency, rate or extent of synapse pruning. go-plus.json regulation of synapse disassembly|regulation of synapse elimination|regulation of synapse clearance|regulation of synapse removal http://purl.obolibrary.org/obo/GO_1905806 goslim_synapse GO:1905807 biolink:BiologicalProcess negative regulation of synapse pruning Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. go-plus.json regulation of synapse disassembly|down regulation of synapse disassembly|downregulation of synapse disassembly|regulation of synapse removal|regulation of synapse elimination|down-regulation of synapse disassembly|inhibition of synapse disassembly|regulation of synapse clearance http://purl.obolibrary.org/obo/GO_1905807 GO:1905808 biolink:BiologicalProcess positive regulation of synapse pruning Any process that activates or increases the frequency, rate or extent of synapse pruning. go-plus.json upregulation of synapse disassembly|regulation of synapse disassembly|regulation of synapse removal|up regulation of synapse disassembly|activation of synapse disassembly|regulation of synapse elimination|up-regulation of synapse disassembly|regulation of synapse clearance http://purl.obolibrary.org/obo/GO_1905808 GO:1905809 biolink:BiologicalProcess negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. go-plus.json inhibition of synapse organization and biogenesis|downregulation of synapse morphogenesis|downregulation of synapse development|down-regulation of synapse organisation|negative regulation of synapse organisation|down regulation of synapse organization and biogenesis|down-regulation of synapse organization|down-regulation of synapse morphogenesis|negative regulation of synapse morphogenesis|down-regulation of synapse development|negative regulation of synapse development|downregulation of synapse organisation|downregulation of synapse organization and biogenesis|down regulation of synapse organisation|inhibition of synapse organisation|inhibition of synapse development|downregulation of synapse organization|negative regulation of synapse organization and biogenesis|down-regulation of synapse organization and biogenesis|inhibition of synapse morphogenesis|down regulation of synapse organization|inhibition of synapse organization|down regulation of synapse morphogenesis|down regulation of synapse development http://purl.obolibrary.org/obo/GO_1905809 GO:0051643 biolink:BiologicalProcess endoplasmic reticulum localization Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell. go-plus.json establishment and maintenance of ER localization|ER localization|endoplasmic reticulum localisation http://purl.obolibrary.org/obo/GO_0051643 GO:0051644 biolink:BiologicalProcess plastid localization Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell. go-plus.json establishment and maintenance of plastid localization|plastid localisation http://purl.obolibrary.org/obo/GO_0051644 GO:0051641 biolink:BiologicalProcess cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. go-plus.json establishment and maintenance of cellular localization|single-organism cellular localization|intracellular localization|localization within cell|establishment and maintenance of localization in cell or cell membrane|cellular localisation|single organism cellular localization http://purl.obolibrary.org/obo/GO_0051641 goslim_pir GO:0051642 biolink:BiologicalProcess centrosome localization Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell. go-plus.json centrosome localisation|establishment and maintenance of centrosome localization http://purl.obolibrary.org/obo/GO_0051642 GO:0051647 biolink:BiologicalProcess nucleus localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. go-plus.json nucleus localisation|cell nucleus localization|localization of nucleus|establishment and maintenance of nucleus localization http://purl.obolibrary.org/obo/GO_0051647 GO:0051648 biolink:BiologicalProcess vesicle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. go-plus.json vesicle localisation|cytoplasmic vesicle localization|establishment and maintenance of vesicle localization http://purl.obolibrary.org/obo/GO_0051648 GO:0051645 biolink:BiologicalProcess Golgi localization Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. go-plus.json establishment and maintenance of Golgi localization|Golgi body localization|Golgi localisation|Golgi apparatus localization http://purl.obolibrary.org/obo/GO_0051645 GO:0051646 biolink:BiologicalProcess mitochondrion localization Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. go-plus.json establishment and maintenance of mitochondrion localization|localization of mitochondria|mitochondrion localisation|localization of mitochondrion|mitochondria localization|establishment and maintenance of mitochondria localization|mitochondrial localization http://purl.obolibrary.org/obo/GO_0051646 GO:0051649 biolink:BiologicalProcess establishment of localization in cell Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. go-plus.json establishment of localisation in cell|establishment of intracellular localization|positioning within cell|establishment of localization within cell|establishment of cellular localization http://purl.obolibrary.org/obo/GO_0051649 GO:1905810 biolink:BiologicalProcess regulation of excitatory synapse pruning Any process that modulates the frequency, rate or extent of excitatory synapse pruning. go-plus.json regulation of synapse clearance|regulation of synapse disassembly|regulation of synapse removal|regulation of synapse elimination http://purl.obolibrary.org/obo/GO_1905810 GO:1905811 biolink:BiologicalProcess negative regulation of excitatory synapse pruning Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning. go-plus.json downregulation of excitatory synapse disassembly|down regulation of excitatory synapse disassembly|regulation of synapse clearance|inhibition of excitatory synapse disassembly|regulation of synapse disassembly|regulation of synapse removal|down-regulation of excitatory synapse disassembly|regulation of synapse elimination http://purl.obolibrary.org/obo/GO_1905811 GO:1905812 biolink:BiologicalProcess regulation of motor neuron axon guidance Any process that modulates the frequency, rate or extent of motor neuron axon guidance. go-plus.json regulation of motor axon pathfinding|regulation of motoneuron axon guidance|regulation of motor axon guidance http://purl.obolibrary.org/obo/GO_1905812 GO:1905813 biolink:BiologicalProcess negative regulation of motor neuron axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance. go-plus.json downregulation of motor axon pathfinding|negative regulation of motor axon guidance|down-regulation of motor axon guidance|down regulation of motor axon pathfinding|downregulation of motor neuron axon guidance|inhibition of motor axon pathfinding|inhibition of motor axon guidance|down regulation of motor neuron axon guidance|inhibition of motor neuron axon guidance|negative regulation of motoneuron axon guidance|down-regulation of motoneuron axon guidance|downregulation of motoneuron axon guidance|down regulation of motor axon guidance|negative regulation of motor axon pathfinding|down-regulation of motor axon pathfinding|down regulation of motoneuron axon guidance|inhibition of motoneuron axon guidance|downregulation of motor axon guidance|down-regulation of motor neuron axon guidance http://purl.obolibrary.org/obo/GO_1905813 GO:1905814 biolink:BiologicalProcess positive regulation of motor neuron axon guidance Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance. go-plus.json up regulation of motor neuron axon guidance|up-regulation of motoneuron axon guidance|activation of motoneuron axon guidance|upregulation of motor axon pathfinding|up-regulation of motor axon guidance|upregulation of motor neuron axon guidance|positive regulation of motoneuron axon guidance|up-regulation of motor axon pathfinding|up regulation of motoneuron axon guidance|upregulation of motor axon guidance|activation of motor axon pathfinding|up-regulation of motor neuron axon guidance|activation of motor neuron axon guidance|upregulation of motoneuron axon guidance|up regulation of motor axon guidance|positive regulation of motor axon pathfinding|positive regulation of motor axon guidance|up regulation of motor axon pathfinding|activation of motor axon guidance http://purl.obolibrary.org/obo/GO_1905814 GO:1905815 biolink:BiologicalProcess regulation of dorsal/ventral axon guidance Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance. go-plus.json regulation of dorsoventral axon guidance|regulation of dorsal/ventral axon pathfinding|regulation of dorsal-ventral axon guidance http://purl.obolibrary.org/obo/GO_1905815 GO:1905816 biolink:BiologicalProcess negative regulation of dorsal/ventral axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance. go-plus.json downregulation of dorsoventral axon guidance|down regulation of dorsal/ventral axon pathfinding|down regulation of dorsoventral axon guidance|inhibition of dorsoventral axon guidance|downregulation of dorsal/ventral axon pathfinding|negative regulation of dorsal-ventral axon guidance|down-regulation of dorsal-ventral axon guidance|down-regulation of dorsal/ventral axon guidance|negative regulation of dorsal/ventral axon pathfinding|down-regulation of dorsal/ventral axon pathfinding|downregulation of dorsal-ventral axon guidance|downregulation of dorsal/ventral axon guidance|down regulation of dorsal-ventral axon guidance|inhibition of dorsal/ventral axon pathfinding|negative regulation of dorsoventral axon guidance|down-regulation of dorsoventral axon guidance|down regulation of dorsal/ventral axon guidance|inhibition of dorsal-ventral axon guidance|inhibition of dorsal/ventral axon guidance http://purl.obolibrary.org/obo/GO_1905816 GO:1905817 biolink:BiologicalProcess positive regulation of dorsal/ventral axon guidance Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance. go-plus.json upregulation of dorsal/ventral axon pathfinding|up-regulation of dorsal-ventral axon guidance|activation of dorsal-ventral axon guidance|up-regulation of dorsal/ventral axon guidance|activation of dorsal/ventral axon guidance|upregulation of dorsoventral axon guidance|up regulation of dorsal/ventral axon pathfinding|positive regulation of dorsal/ventral axon pathfinding|activation of dorsal/ventral axon pathfinding|positive regulation of dorsal-ventral axon guidance|up regulation of dorsal-ventral axon guidance|up-regulation of dorsoventral axon guidance|activation of dorsoventral axon guidance|up regulation of dorsal/ventral axon guidance|up-regulation of dorsal/ventral axon pathfinding|upregulation of dorsal-ventral axon guidance|positive regulation of dorsoventral axon guidance|upregulation of dorsal/ventral axon guidance|up regulation of dorsoventral axon guidance http://purl.obolibrary.org/obo/GO_1905817 GO:1905818 biolink:BiologicalProcess regulation of chromosome separation Any process that modulates the frequency, rate or extent of chromosome separation. go-plus.json regulation of rDNA separation|regulation of chromatid release http://purl.obolibrary.org/obo/GO_1905818 GO:1905819 biolink:BiologicalProcess negative regulation of chromosome separation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation. go-plus.json negative regulation of chromatid release|down-regulation of chromatid release|down regulation of chromosome separation|inhibition of rDNA separation|downregulation of chromosome separation|down regulation of rDNA separation|inhibition of chromatid release|downregulation of rDNA separation|down-regulation of chromosome separation|down regulation of chromatid release|inhibition of chromosome separation|negative regulation of rDNA separation|down-regulation of rDNA separation|downregulation of chromatid release http://purl.obolibrary.org/obo/GO_1905819 GO:0051640 biolink:BiologicalProcess organelle localization Any process in which an organelle is transported to, and/or maintained in, a specific location. go-plus.json establishment and maintenance of organelle localization|organelle localisation http://purl.obolibrary.org/obo/GO_0051640 goslim_pir GO:0051654 biolink:BiologicalProcess establishment of mitochondrion localization The directed movement of the mitochondrion to a specific location. go-plus.json establishment of mitochondrion localisation|mitochondria positioning|mitochondrial migration|establishment of mitochondria localization|mitochondrion positioning http://purl.obolibrary.org/obo/GO_0051654 GO:0002687 biolink:BiologicalProcess positive regulation of leukocyte migration Any process that activates or increases the frequency, rate, or extent of leukocyte migration. go-plus.json positive regulation of leucocyte migration|up regulation of leukocyte migration|activation of leukocyte migration|stimulation of leukocyte migration|positive regulation of immune cell migration|up-regulation of leukocyte migration|upregulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0002687 GO:0051655 biolink:BiologicalProcess maintenance of vesicle location Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of vesicle localization http://purl.obolibrary.org/obo/GO_0051655 GO:0002688 biolink:BiologicalProcess regulation of leukocyte chemotaxis Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis. go-plus.json regulation of leucocyte chemotaxis|regulation of immune cell chemotaxis http://purl.obolibrary.org/obo/GO_0002688 GO:0002689 biolink:BiologicalProcess negative regulation of leukocyte chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. go-plus.json negative regulation of leucocyte chemotaxis|downregulation of leukocyte chemotaxis|down regulation of leukocyte chemotaxis|inhibition of leukocyte chemotaxis|negative regulation of immune cell chemotaxis|down-regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002689 GO:0051652 biolink:BiologicalProcess maintenance of chromosome location Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of chromosome localization http://purl.obolibrary.org/obo/GO_0051652 GO:0051653 biolink:BiologicalProcess spindle localization Any process in which is the spindle is transported to, and/or maintained in, a specific location. go-plus.json establishment and maintenance of spindle localization|spindle localisation http://purl.obolibrary.org/obo/GO_0051653 GO:0002683 biolink:BiologicalProcess negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. go-plus.json down-regulation of immune system process|inhibition of immune system process|down regulation of immune system process|downregulation of immune system process http://purl.obolibrary.org/obo/GO_0002683 GO:0051658 biolink:BiologicalProcess maintenance of nucleus location Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of nucleus localization|maintenance of cell nucleus location http://purl.obolibrary.org/obo/GO_0051658 GO:0002684 biolink:BiologicalProcess positive regulation of immune system process Any process that activates or increases the frequency, rate, or extent of an immune system process. go-plus.json activation of immune system process|stimulation of immune system process|up-regulation of immune system process|upregulation of immune system process|up regulation of immune system process http://purl.obolibrary.org/obo/GO_0002684 GO:0051659 biolink:BiologicalProcess maintenance of mitochondrion location Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of mitochondrion localization|maintenance of mitochondria localization http://purl.obolibrary.org/obo/GO_0051659 GO:0002685 biolink:BiologicalProcess regulation of leukocyte migration Any process that modulates the frequency, rate, or extent of leukocyte migration. go-plus.json regulation of immune cell migration|regulation of leucocyte migration http://purl.obolibrary.org/obo/GO_0002685 GO:0051656 biolink:BiologicalProcess establishment of organelle localization The directed movement of an organelle to a specific location. go-plus.json establishment of organelle localisation http://purl.obolibrary.org/obo/GO_0051656 GO:0002686 biolink:BiologicalProcess negative regulation of leukocyte migration Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. go-plus.json downregulation of leukocyte migration|negative regulation of leucocyte migration|down-regulation of leukocyte migration|inhibition of leukocyte migration|negative regulation of immune cell migration|down regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0002686 GO:0051657 biolink:BiologicalProcess maintenance of organelle location Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of organelle localization http://purl.obolibrary.org/obo/GO_0051657 GO:0002680 biolink:BiologicalProcess pro-T cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell. go-plus.json pro-T lymphocyte lineage commitment|pro-T cell fate commitment|pro-T lymphocyte fate commitment http://purl.obolibrary.org/obo/GO_0002680 GO:0002681 biolink:BiologicalProcess somatic recombination of T cell receptor gene segments The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments. go-plus.json somatic recombination of TCR gene segments http://purl.obolibrary.org/obo/GO_0002681 GO:0002682 biolink:BiologicalProcess regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process. go-plus.json http://purl.obolibrary.org/obo/GO_0002682 GO:1905820 biolink:BiologicalProcess positive regulation of chromosome separation Any process that activates or increases the frequency, rate or extent of chromosome separation. go-plus.json activation of rDNA separation|up regulation of chromatid release|positive regulation of chromatid release|up-regulation of rDNA separation|upregulation of chromosome separation|activation of chromatid release|upregulation of rDNA separation|up-regulation of chromatid release|up regulation of chromosome separation|activation of chromosome separation|up regulation of rDNA separation|upregulation of chromatid release|positive regulation of rDNA separation|up-regulation of chromosome separation http://purl.obolibrary.org/obo/GO_1905820 GO:1905821 biolink:BiologicalProcess positive regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. go-plus.json upregulation of chromosome condensation|activation of eukaryotic chromosome condensation|up-regulation of eukaryotic chromosome condensation|up regulation of nuclear chromosome condensation|activation of nuclear chromosome condensation|positive regulation of nuclear chromosome condensation|up regulation of chromosome condensation|activation of chromosome condensation|positive regulation of eukaryotic chromosome condensation|up regulation of eukaryotic chromosome condensation|up-regulation of nuclear chromosome condensation|up-regulation of chromosome condensation|upregulation of eukaryotic chromosome condensation|upregulation of nuclear chromosome condensation http://purl.obolibrary.org/obo/GO_1905821 GO:1905822 biolink:BiologicalProcess regulation of mitotic sister chromatid arm separation Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation. go-plus.json http://purl.obolibrary.org/obo/GO_1905822 GO:1905823 biolink:BiologicalProcess negative regulation of mitotic sister chromatid arm separation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation. go-plus.json down-regulation of mitotic sister chromatid arm separation|inhibition of mitotic sister chromatid arm separation|down regulation of mitotic sister chromatid arm separation|downregulation of mitotic sister chromatid arm separation http://purl.obolibrary.org/obo/GO_1905823 GO:1905824 biolink:BiologicalProcess positive regulation of mitotic sister chromatid arm separation Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation. go-plus.json activation of mitotic sister chromatid arm separation|up-regulation of mitotic sister chromatid arm separation|upregulation of mitotic sister chromatid arm separation|up regulation of mitotic sister chromatid arm separation http://purl.obolibrary.org/obo/GO_1905824 GO:1905825 biolink:BiologicalProcess regulation of selenocysteine metabolic process Any process that modulates the frequency, rate or extent of selenocysteine metabolic process. go-plus.json regulation of selenocysteine metabolism http://purl.obolibrary.org/obo/GO_1905825 GO:1905826 biolink:BiologicalProcess negative regulation of selenocysteine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process. go-plus.json inhibition of selenocysteine metabolism|down-regulation of selenocysteine metabolic process|down regulation of selenocysteine metabolism|downregulation of selenocysteine metabolic process|downregulation of selenocysteine metabolism|down regulation of selenocysteine metabolic process|inhibition of selenocysteine metabolic process|down-regulation of selenocysteine metabolism|negative regulation of selenocysteine metabolism http://purl.obolibrary.org/obo/GO_1905826 GO:1905827 biolink:BiologicalProcess positive regulation of selenocysteine metabolic process Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process. go-plus.json up-regulation of selenocysteine metabolism|up-regulation of selenocysteine metabolic process|activation of selenocysteine metabolic process|upregulation of selenocysteine metabolism|up regulation of selenocysteine metabolic process|up regulation of selenocysteine metabolism|activation of selenocysteine metabolism|positive regulation of selenocysteine metabolism|upregulation of selenocysteine metabolic process http://purl.obolibrary.org/obo/GO_1905827 GO:1905828 biolink:BiologicalProcess regulation of prostaglandin catabolic process Any process that modulates the frequency, rate or extent of prostaglandin catabolic process. go-plus.json regulation of prostaglandin catabolism|regulation of prostaglandin degradation|regulation of prostaglandin breakdown http://purl.obolibrary.org/obo/GO_1905828 GO:1905829 biolink:BiologicalProcess negative regulation of prostaglandin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process. go-plus.json downregulation of prostaglandin catabolic process|down-regulation of prostaglandin degradation|negative regulation of prostaglandin degradation|negative regulation of prostaglandin catabolism|down-regulation of prostaglandin catabolism|down-regulation of prostaglandin breakdown|negative regulation of prostaglandin breakdown|inhibition of prostaglandin degradation|down-regulation of prostaglandin catabolic process|inhibition of prostaglandin breakdown|downregulation of prostaglandin catabolism|down regulation of prostaglandin catabolism|inhibition of prostaglandin catabolic process|inhibition of prostaglandin catabolism|down regulation of prostaglandin degradation|downregulation of prostaglandin degradation|down regulation of prostaglandin breakdown|downregulation of prostaglandin breakdown|down regulation of prostaglandin catabolic process http://purl.obolibrary.org/obo/GO_1905829 GO:0051650 biolink:BiologicalProcess establishment of vesicle localization The directed movement of a vesicle to a specific location. go-plus.json establishment of vesicle localisation http://purl.obolibrary.org/obo/GO_0051650 goslim_aspergillus GO:0051651 biolink:BiologicalProcess maintenance of location in cell Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. go-plus.json maintenance of intracellular localization|maintenance of localization within cell|cellular retention|intracellular retention|cellular storage|intracellular storage|intracellular sequestering|sequestering within cell|cellular sequestering|retention within cell|maintenance of cellular localization|maintenance of localization in cell|storage within cell http://purl.obolibrary.org/obo/GO_0051651 GO:0002698 biolink:BiologicalProcess negative regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. go-plus.json down regulation of immune effector process|downregulation of immune effector process|down-regulation of immune effector process|inhibition of immune effector process http://purl.obolibrary.org/obo/GO_0002698 GO:0051665 biolink:BiologicalProcess membrane raft localization Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. go-plus.json establishment and maintenance of membrane raft localization|membrane raft localisation|lipid raft localization http://purl.obolibrary.org/obo/GO_0051665 GO:0002699 biolink:BiologicalProcess positive regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. go-plus.json upregulation of immune effector process|up regulation of immune effector process|activation of immune effector process|stimulation of immune effector process|up-regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002699 GO:0051666 biolink:BiologicalProcess actin cortical patch localization Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells. go-plus.json actin cortical patch localisation|establishment and maintenance of actin cortical patch localization http://purl.obolibrary.org/obo/GO_0051666 GO:0051663 biolink:BiologicalProcess oocyte nucleus localization involved in oocyte dorsal/ventral axis specification The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte. go-plus.json oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte axis determination, oocyte nucleus localization|establishment and maintenance of oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|oocyte nucleus localization involved in oocyte dorsoventral axis specification http://purl.obolibrary.org/obo/GO_0051663 GO:0051664 biolink:BiologicalProcess nuclear pore localization Any process in which nuclear pores are transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of nuclear pore localization|positioning of nuclear pores|nuclear pore distribution|nuclear pore localisation http://purl.obolibrary.org/obo/GO_0051664 GO:0051669 biolink:MolecularActivity fructan beta-fructosidase activity Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans. MetaCyc:3.2.1.80-RXN|EC:3.2.1.80 go-plus.json fructanase activity|exo-beta-D-fructosidase activity|fructan exohydrolase activity|fructan b-fructosidase activity|beta-D-fructan fructohydrolase activity|polysaccharide beta-fructofuranosidase activity|exo-beta-fructosidase activity http://purl.obolibrary.org/obo/GO_0051669 GO:0002694 biolink:BiologicalProcess regulation of leukocyte activation Any process that modulates the frequency, rate, or extent of leukocyte activation. go-plus.json regulation of immune cell activation|regulation of leucocyte activation http://purl.obolibrary.org/obo/GO_0002694 CHEBI:99 biolink:ChemicalSubstance (-)-maackiain go-plus.json http://purl.obolibrary.org/obo/CHEBI_99 chebi_ph7_3 GO:0002695 biolink:BiologicalProcess negative regulation of leukocyte activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. go-plus.json down-regulation of leukocyte activation|negative regulation of leucocyte activation|downregulation of leukocyte activation|down regulation of leukocyte activation|inhibition of leukocyte activation|negative regulation of immune cell activation http://purl.obolibrary.org/obo/GO_0002695 GO:0002696 biolink:BiologicalProcess positive regulation of leukocyte activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. go-plus.json positive regulation of immune cell activation|up regulation of leukocyte activation|positive regulation of leucocyte activation|upregulation of leukocyte activation|stimulation of leukocyte activation|up-regulation of leukocyte activation|activation of leukocyte activation http://purl.obolibrary.org/obo/GO_0002696 GO:0051667 biolink:BiologicalProcess establishment of plastid localization The directed movement of a plastid to a specific location in the cell. go-plus.json establishment of plastid localisation http://purl.obolibrary.org/obo/GO_0051667 GO:0051668 biolink:BiologicalProcess localization within membrane Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. go-plus.json positioning within membrane|localisation within membrane|establishment and maintenance of position in membrane|localization to membrane|establishment and maintenance of localization in membrane http://purl.obolibrary.org/obo/GO_0051668 GO:0002697 biolink:BiologicalProcess regulation of immune effector process Any process that modulates the frequency, rate, or extent of an immune effector process. go-plus.json http://purl.obolibrary.org/obo/GO_0002697 GO:0002690 biolink:BiologicalProcess positive regulation of leukocyte chemotaxis Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis. go-plus.json positive regulation of immune cell chemotaxis|up regulation of leukocyte chemotaxis|positive regulation of leucocyte chemotaxis|upregulation of leukocyte chemotaxis|stimulation of leukocyte chemotaxis|up-regulation of leukocyte chemotaxis|activation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002690 GO:0002691 biolink:BiologicalProcess regulation of cellular extravasation Any process that modulates the frequency, rate, or extent of cellular extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_0002691 GO:0002692 biolink:BiologicalProcess negative regulation of cellular extravasation Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation. go-plus.json down-regulation of cellular extravasation|downregulation of cellular extravasation|down regulation of cellular extravasation|inhibition of cellular extravasation http://purl.obolibrary.org/obo/GO_0002692 GO:0002693 biolink:BiologicalProcess positive regulation of cellular extravasation Any process that activates or increases the frequency, rate, or extent of cellular extravasation. go-plus.json stimulation of cellular extravasation|up-regulation of cellular extravasation|activation of cellular extravasation|up regulation of cellular extravasation|upregulation of cellular extravasation http://purl.obolibrary.org/obo/GO_0002693 CHEBI:98 biolink:ChemicalSubstance (S)-linalool go-plus.json http://purl.obolibrary.org/obo/CHEBI_98 chebi_ph7_3 GO:1905830 biolink:BiologicalProcess positive regulation of prostaglandin catabolic process Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process. go-plus.json upregulation of prostaglandin catabolic process|up regulation of prostaglandin degradation|positive regulation of prostaglandin degradation|activation of prostaglandin degradation|up-regulation of prostaglandin catabolism|activation of prostaglandin catabolism|up regulation of prostaglandin breakdown|activation of prostaglandin breakdown|positive regulation of prostaglandin breakdown|up regulation of prostaglandin catabolic process|activation of prostaglandin catabolic process|positive regulation of prostaglandin catabolism|up-regulation of prostaglandin degradation|up regulation of prostaglandin catabolism|up-regulation of prostaglandin breakdown|up-regulation of prostaglandin catabolic process|upregulation of prostaglandin degradation|upregulation of prostaglandin catabolism|upregulation of prostaglandin breakdown http://purl.obolibrary.org/obo/GO_1905830 GO:1905831 biolink:BiologicalProcess negative regulation of spindle assembly Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly. go-plus.json downregulation of spindle formation|down regulation of bipolar spindle formation|down-regulation of spindle biosynthesis|negative regulation of spindle biosynthesis|downregulation of bipolar spindle biosynthesis|down-regulation of spindle formation|downregulation of bipolar spindle formation|negative regulation of spindle formation|down regulation of bipolar spindle biosynthesis|inhibition of bipolar spindle biosynthesis|down-regulation of spindle assembly|inhibition of spindle formation|downregulation of spindle biosynthesis|negative regulation of bipolar spindle formation|down-regulation of bipolar spindle formation|down regulation of spindle biosynthesis|inhibition of spindle biosynthesis|downregulation of spindle assembly|inhibition of bipolar spindle formation|down regulation of spindle assembly|down regulation of spindle formation|inhibition of spindle assembly|negative regulation of bipolar spindle biosynthesis|down-regulation of bipolar spindle biosynthesis http://purl.obolibrary.org/obo/GO_1905831 GO:1905832 biolink:BiologicalProcess positive regulation of spindle assembly Any process that activates or increases the frequency, rate or extent of spindle assembly. go-plus.json up-regulation of spindle biosynthesis|activation of spindle biosynthesis|upregulation of bipolar spindle formation|up regulation of spindle formation|positive regulation of bipolar spindle biosynthesis|up regulation of bipolar spindle biosynthesis|activation of spindle formation|positive regulation of spindle formation|up-regulation of spindle assembly|activation of spindle assembly|up regulation of bipolar spindle formation|positive regulation of spindle biosynthesis|up regulation of spindle biosynthesis|activation of bipolar spindle formation|positive regulation of bipolar spindle formation|upregulation of bipolar spindle biosynthesis|up-regulation of spindle formation|up regulation of spindle assembly|upregulation of spindle biosynthesis|up-regulation of bipolar spindle biosynthesis|up-regulation of bipolar spindle formation|activation of bipolar spindle biosynthesis|upregulation of spindle formation|upregulation of spindle assembly http://purl.obolibrary.org/obo/GO_1905832 GO:1905833 biolink:BiologicalProcess negative regulation of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. go-plus.json down-regulation of microtubule nucleation|downregulation of microtubule nucleation|down regulation of microtubule nucleation|inhibition of microtubule nucleation http://purl.obolibrary.org/obo/GO_1905833 GO:1905834 biolink:BiologicalProcess response to pyrimidine ribonucleotide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905834 GO:1905835 biolink:BiologicalProcess cellular response to pyrimidine ribonucleotide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905835 GO:1905836 biolink:BiologicalProcess response to triterpenoid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905836 GO:1905837 biolink:BiologicalProcess cellular response to triterpenoid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905837 GO:1905838 biolink:BiologicalProcess regulation of telomeric D-loop disassembly Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly. go-plus.json http://purl.obolibrary.org/obo/GO_1905838 GO:1905839 biolink:BiologicalProcess negative regulation of telomeric D-loop disassembly Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly. go-plus.json downregulation of telomeric D-loop disassembly|down regulation of telomeric D-loop disassembly|inhibition of telomeric D-loop disassembly|down-regulation of telomeric D-loop disassembly http://purl.obolibrary.org/obo/GO_1905839 GO:0051661 biolink:BiologicalProcess maintenance of centrosome location Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of centrosome localization http://purl.obolibrary.org/obo/GO_0051661 GO:0051662 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051662 GO:0051660 biolink:BiologicalProcess establishment of centrosome localization The directed movement of the centrosome to a specific location. go-plus.json establishment of centrosome localisation|centrosome positioning http://purl.obolibrary.org/obo/GO_0051660 GO:0002665 biolink:BiologicalProcess negative regulation of T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction. go-plus.json negative regulation of T-lymphocyte tolerance induction|down-regulation of T cell tolerance induction|negative regulation of T lymphocyte tolerance induction|downregulation of T cell tolerance induction|down regulation of T cell tolerance induction|inhibition of T cell tolerance induction|negative regulation of T-cell tolerance induction http://purl.obolibrary.org/obo/GO_0002665 GO:0099610 biolink:BiologicalProcess action potential initiation The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate. go-plus.json action potential firing|action potential triggering http://purl.obolibrary.org/obo/GO_0099610 GO:0051676 biolink:BiologicalProcess pullulan metabolic process The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. go-plus.json pullulan metabolism http://purl.obolibrary.org/obo/GO_0051676 GO:0051677 biolink:BiologicalProcess pullulan biosynthetic process The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0051677 GO:0002666 biolink:BiologicalProcess positive regulation of T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction. go-plus.json stimulation of T cell tolerance induction|positive regulation of T-cell tolerance induction|activation of T cell tolerance induction|up-regulation of T cell tolerance induction|positive regulation of T-lymphocyte tolerance induction|up regulation of T cell tolerance induction|positive regulation of T lymphocyte tolerance induction|upregulation of T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002666 GO:0099611 biolink:BiologicalProcess regulation of action potential firing threshold Any process that regulates the potential at which an axon potential is triggered. go-plus.json http://purl.obolibrary.org/obo/GO_0099611 GO:0051674 biolink:BiologicalProcess localization of cell Any process in which a cell is transported to, and/or maintained in, a specific location. go-plus.json establishment and maintenance of localization of cell|establishment and maintenance of cell localization|localisation of cell|cell localization http://purl.obolibrary.org/obo/GO_0051674 GO:0002667 biolink:BiologicalProcess regulation of T cell anergy Any process that modulates the frequency, rate, or extent of T cell anergy. go-plus.json regulation of T-lymphocyte anergy|regulation of T-cell anergy|regulation of T lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002667 GO:0051675 biolink:MolecularActivity isopullulanase activity Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose). EC:3.2.1.57|MetaCyc:3.2.1.57-RXN go-plus.json pullulan 4-glucanohydrolase (isopanose-forming) activity http://purl.obolibrary.org/obo/GO_0051675 GO:0002668 biolink:BiologicalProcess negative regulation of T cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy. go-plus.json negative regulation of T lymphocyte anergy|down-regulation of T cell anergy|inhibition of T cell anergy|negative regulation of T-lymphocyte anergy|negative regulation of T-cell anergy|down regulation of T cell anergy|downregulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002668 GO:0002661 biolink:BiologicalProcess regulation of B cell tolerance induction Any process that modulates the frequency, rate, or extent of B cell tolerance induction. go-plus.json regulation of B lymphocyte tolerance induction|regulation of B-cell tolerance induction|regulation of B-lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002661 CHEBI:51389 biolink:ChemicalSubstance calixpyrroles go-plus.json http://purl.obolibrary.org/obo/CHEBI_51389 GO:0002662 biolink:BiologicalProcess negative regulation of B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction. go-plus.json downregulation of B cell tolerance induction|down regulation of B cell tolerance induction|inhibition of B cell tolerance induction|negative regulation of B-cell tolerance induction|negative regulation of B-lymphocyte tolerance induction|down-regulation of B cell tolerance induction|negative regulation of B lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002662 GO:0002663 biolink:BiologicalProcess positive regulation of B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction. go-plus.json positive regulation of B lymphocyte tolerance induction|upregulation of B cell tolerance induction|positive regulation of B-cell tolerance induction|stimulation of B cell tolerance induction|up-regulation of B cell tolerance induction|activation of B cell tolerance induction|positive regulation of B-lymphocyte tolerance induction|up regulation of B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002663 GO:0051678 biolink:BiologicalProcess pullulan catabolic process The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0051678 GO:0051679 biolink:BiologicalProcess 6-alpha-maltosylglucose metabolic process The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose. go-plus.json 6-alpha-maltosylglucose metabolism|isopanose metabolic process|isopanose metabolism http://purl.obolibrary.org/obo/GO_0051679 GO:0002664 biolink:BiologicalProcess regulation of T cell tolerance induction Any process that modulates the frequency, rate, or extent of T cell tolerance induction. go-plus.json regulation of T-cell tolerance induction|regulation of T-lymphocyte tolerance induction|regulation of T lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002664 GO:0002660 biolink:BiologicalProcess positive regulation of peripheral tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction. go-plus.json up regulation of peripheral tolerance induction|upregulation of peripheral tolerance induction|stimulation of peripheral tolerance induction|activation of peripheral tolerance induction|up-regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002660 GO:0061000 biolink:BiologicalProcess negative regulation of dendritic spine development Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061000 GO:0061001 biolink:BiologicalProcess regulation of dendritic spine morphogenesis Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0061001 GO:1905850 biolink:BiologicalProcess positive regulation of forward locomotion Any process that activates or increases the frequency, rate or extent of forward locomotion. go-plus.json upregulation of forward locomotion|up-regulation of forward locomotion|activation of forward locomotion|up regulation of forward locomotion http://purl.obolibrary.org/obo/GO_1905850 GO:0061002 biolink:BiologicalProcess negative regulation of dendritic spine morphogenesis Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0061002 GO:1905840 biolink:BiologicalProcess positive regulation of telomeric D-loop disassembly Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly. go-plus.json up regulation of telomeric D-loop disassembly|upregulation of telomeric D-loop disassembly|up-regulation of telomeric D-loop disassembly|activation of telomeric D-loop disassembly http://purl.obolibrary.org/obo/GO_1905840 GO:1905841 biolink:BiologicalProcess response to oxidopamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905841 GO:0061003 biolink:BiologicalProcess positive regulation of dendritic spine morphogenesis Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0061003 GO:1905842 biolink:BiologicalProcess cellular response to oxidopamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905842 GO:0061004 biolink:BiologicalProcess pattern specification involved in kidney development Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate. go-plus.json pattern formation involved in kidney development|kidney pattern specification|kidney pattern formation http://purl.obolibrary.org/obo/GO_0061004 GO:1905843 biolink:BiologicalProcess regulation of cellular response to gamma radiation Any process that modulates the frequency, rate or extent of cellular response to gamma radiation. go-plus.json regulation of cellular response to gamma ray|regulation of cellular response to gamma-ray photon http://purl.obolibrary.org/obo/GO_1905843 GO:0061005 biolink:BiologicalProcess cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061005 GO:1905844 biolink:BiologicalProcess negative regulation of cellular response to gamma radiation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation. go-plus.json downregulation of cellular response to gamma ray|inhibition of cellular response to gamma-ray photon|down regulation of cellular response to gamma ray|downregulation of cellular response to gamma radiation|down regulation of cellular response to gamma-ray photon|down regulation of cellular response to gamma radiation|inhibition of cellular response to gamma radiation|downregulation of cellular response to gamma-ray photon|inhibition of cellular response to gamma ray|down-regulation of cellular response to gamma-ray photon|negative regulation of cellular response to gamma-ray photon|down-regulation of cellular response to gamma ray|negative regulation of cellular response to gamma ray|down-regulation of cellular response to gamma radiation http://purl.obolibrary.org/obo/GO_1905844 GO:0061006 biolink:BiologicalProcess regulation of cell proliferation involved in kidney morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0061006 GO:1905845 biolink:BiologicalProcess positive regulation of cellular response to gamma radiation Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation. go-plus.json up regulation of cellular response to gamma radiation|upregulation of cellular response to gamma-ray photon|upregulation of cellular response to gamma ray|upregulation of cellular response to gamma radiation|up regulation of cellular response to gamma-ray photon|up-regulation of cellular response to gamma ray|positive regulation of cellular response to gamma-ray photon|activation of cellular response to gamma radiation|up-regulation of cellular response to gamma radiation|activation of cellular response to gamma-ray photon|activation of cellular response to gamma ray|positive regulation of cellular response to gamma ray|up-regulation of cellular response to gamma-ray photon|up regulation of cellular response to gamma ray http://purl.obolibrary.org/obo/GO_1905845 GO:0061007 biolink:BiologicalProcess hepaticobiliary system process An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. go-plus.json hepatobiliary system process http://purl.obolibrary.org/obo/GO_0061007 GO:0061008 biolink:BiologicalProcess hepaticobiliary system development The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. go-plus.json hepatobiliary system development http://purl.obolibrary.org/obo/GO_0061008 GO:1905846 biolink:BiologicalProcess regulation of cellular response to oxidopamine Any process that modulates the frequency, rate or extent of cellular response to oxidopamine. go-plus.json http://purl.obolibrary.org/obo/GO_1905846 GO:1905847 biolink:BiologicalProcess negative regulation of cellular response to oxidopamine Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine. go-plus.json downregulation of cellular response to oxidopamine|down regulation of cellular response to oxidopamine|inhibition of cellular response to oxidopamine|down-regulation of cellular response to oxidopamine http://purl.obolibrary.org/obo/GO_1905847 GO:0061009 biolink:BiologicalProcess common bile duct development The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine. go-plus.json extrahepatic bile duct development|CBD development|bile duct development|EHBD development http://purl.obolibrary.org/obo/GO_0061009 GO:1905848 biolink:BiologicalProcess positive regulation of cellular response to oxidopamine Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine. go-plus.json upregulation of cellular response to oxidopamine|up-regulation of cellular response to oxidopamine|activation of cellular response to oxidopamine|up regulation of cellular response to oxidopamine http://purl.obolibrary.org/obo/GO_1905848 GO:0099618 biolink:MolecularActivity UDP-glucuronic acid dehydrogenase activity Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+. RHEA:24702|EC:1.1.1.305 go-plus.json UDP-GlcUA decarboxylase activity http://purl.obolibrary.org/obo/GO_0099618 GO:1905849 biolink:BiologicalProcess negative regulation of forward locomotion Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion. go-plus.json down-regulation of forward locomotion|downregulation of forward locomotion|down regulation of forward locomotion|inhibition of forward locomotion http://purl.obolibrary.org/obo/GO_1905849 GO:0099619 biolink:MolecularActivity UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. EC:2.1.2.13|RHEA:24706 go-plus.json UDP-L-Ara4N formyltransferase activity|10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity|ArnAFT activity http://purl.obolibrary.org/obo/GO_0099619 CHEBI:51387 biolink:ChemicalSubstance calix(hetero)arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51387 GO:0099616 biolink:CellularComponent extrinsic component of matrix side of mitochondrial inner membrane The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0099616 GO:0099617 biolink:CellularComponent matrix side of mitochondrial inner membrane The side (leaflet) of the mitochondrial inner membrane that faces the matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0099617 GO:0002669 biolink:BiologicalProcess positive regulation of T cell anergy Any process that activates or increases the frequency, rate, or extent of T cell anergy. go-plus.json positive regulation of T lymphocyte anergy|up regulation of T cell anergy|activation of T cell anergy|stimulation of T cell anergy|positive regulation of T-lymphocyte anergy|up-regulation of T cell anergy|positive regulation of T-cell anergy|upregulation of T cell anergy http://purl.obolibrary.org/obo/GO_0002669 GO:0051672 biolink:BiologicalProcess obsolete catabolism by organism of cell wall peptidoglycan in other organism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism. go-plus.json cell wall catabolism in other organism|cell wall catabolic process in other organism|cell wall peptidoglycan catabolic process in another organism|catabolic process of cell wall peptidoglycans of other organism|catabolism of cell wall peptidoglycans of other organism http://purl.obolibrary.org/obo/GO_0051672 GO:0099614 biolink:BiologicalProcess protein localization to spore cell wall A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall. go-plus.json protein targeting to spore cell wall http://purl.obolibrary.org/obo/GO_0099614 GO:0051673 biolink:BiologicalProcess membrane disruption in other organism The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism. go-plus.json cytolysis, by membrane disruption, in other organism|membrane disruption in another organism http://purl.obolibrary.org/obo/GO_0051673 GO:0099615 biolink:MolecularActivity (D)-2-hydroxyglutarate-pyruvate transhydrogenase activity Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor. go-plus.json D-2HG-pyruvate transhydrogenase activity|R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity http://purl.obolibrary.org/obo/GO_0099615 GO:0099612 biolink:BiologicalProcess protein localization to axon A process in which a protein is transported to or maintained in a location within an axon. go-plus.json http://purl.obolibrary.org/obo/GO_0099612 GO:0051670 biolink:MolecularActivity inulinase activity Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin. MetaCyc:3.2.1.7-RXN|EC:3.2.1.7 go-plus.json indoinulinase activity|2,1-beta-D-fructan fructanohydrolase activity|exoinulinase activity|inulase activity|endo-inulinase activity http://purl.obolibrary.org/obo/GO_0051670 GO:0051671 biolink:BiologicalProcess obsolete induction of autolysin activity in other organism OBSOLETE. Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism. go-plus.json positive regulation of autolysin activity in another organism|induction of autolytic activity in other organism|activation of autolysis in other organism|activation of autolytic activity in other organism|activation of autolysin activity in another organism|induction of autolysis in other organism|induction of autolysin activity in another organism http://purl.obolibrary.org/obo/GO_0051671 GO:0099613 biolink:BiologicalProcess protein localization to cell wall The process of directing proteins towards the cell-wall. go-plus.json http://purl.obolibrary.org/obo/GO_0099613 CHEBI:51384 biolink:ChemicalSubstance D-ascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51384 GO:0099621 biolink:MolecularActivity undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate. MetaCyc:RXN0-3521|EC:2.4.2.53|RHEA:27722 go-plus.json undecaprenyl-phosphate Ara4FN transferase activity|undecaprenyl phosphate-L-Ara4FN transferase activity|Ara4FN transferase activity http://purl.obolibrary.org/obo/GO_0099621 GO:0051687 biolink:BiologicalProcess maintenance of spindle location Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of spindle localization http://purl.obolibrary.org/obo/GO_0051687 GO:0002676 biolink:BiologicalProcess regulation of chronic inflammatory response Any process that modulates the frequency, rate, or extent of a chronic inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0002676 GO:0002677 biolink:BiologicalProcess negative regulation of chronic inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response. go-plus.json inhibition of chronic inflammatory response|down regulation of chronic inflammatory response|downregulation of chronic inflammatory response|down-regulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0002677 GO:0099622 biolink:BiologicalProcess cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0099622 GO:0051688 biolink:BiologicalProcess maintenance of plastid location Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of plastid localization http://purl.obolibrary.org/obo/GO_0051688 GO:0002678 biolink:BiologicalProcess positive regulation of chronic inflammatory response Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response. go-plus.json up-regulation of chronic inflammatory response|upregulation of chronic inflammatory response|up regulation of chronic inflammatory response|activation of chronic inflammatory response|stimulation of chronic inflammatory response http://purl.obolibrary.org/obo/GO_0002678 GO:0051685 biolink:BiologicalProcess maintenance of ER location Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of ER localization|maintenance of endoplasmic reticulum localization http://purl.obolibrary.org/obo/GO_0051685 GO:0051686 biolink:BiologicalProcess establishment of ER localization The directed movement of the endoplasmic reticulum to a specific location. go-plus.json establishment of ER localisation|establishment of endoplasmic reticulum localization http://purl.obolibrary.org/obo/GO_0051686 GO:0099620 biolink:MolecularActivity UDP-4-amino-4-deoxy-L-arabinose aminotransferase Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate. EC:2.6.1.87|RHEA:24710 go-plus.json UDP-L-Ara4N transaminase|UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase|UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase|UDP-Ara4O aminotransferase|UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase http://purl.obolibrary.org/obo/GO_0099620 GO:0002679 biolink:BiologicalProcess respiratory burst involved in defense response A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0002679 GO:0002672 biolink:BiologicalProcess positive regulation of B cell anergy Any process that activates or increases the frequency, rate, or extent of B cell anergy. go-plus.json activation of B cell anergy|stimulation of B cell anergy|positive regulation of B-lymphocyte anergy|up-regulation of B cell anergy|positive regulation of B-cell anergy|upregulation of B cell anergy|positive regulation of B lymphocyte anergy|up regulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002672 GO:0002673 biolink:BiologicalProcess regulation of acute inflammatory response Any process that modulates the frequency, rate, or extent of an acute inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0002673 GO:0002674 biolink:BiologicalProcess negative regulation of acute inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. go-plus.json inhibition of acute inflammatory response|down regulation of acute inflammatory response|downregulation of acute inflammatory response|down-regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0002674 GO:0051689 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051689 GO:0002675 biolink:BiologicalProcess positive regulation of acute inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. go-plus.json up-regulation of acute inflammatory response|upregulation of acute inflammatory response|up regulation of acute inflammatory response|activation of acute inflammatory response|stimulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0002675 GO:0002670 biolink:BiologicalProcess regulation of B cell anergy Any process that modulates the frequency, rate, or extent of B cell anergy. go-plus.json regulation of B-lymphocyte anergy|regulation of B-cell anergy|regulation of B lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002670 GO:0002671 biolink:BiologicalProcess negative regulation of B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy. go-plus.json negative regulation of B lymphocyte anergy|down-regulation of B cell anergy|inhibition of B cell anergy|negative regulation of B-lymphocyte anergy|negative regulation of B-cell anergy|down regulation of B cell anergy|downregulation of B cell anergy http://purl.obolibrary.org/obo/GO_0002671 GO:1905860 biolink:BiologicalProcess positive regulation of heparan sulfate proteoglycan binding Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding. go-plus.json positive regulation of heparin proteoglycan binding|up regulation of heparin proteoglycan binding|upregulation of heparan sulfate proteoglycan binding|upregulation of heparin proteoglycan binding|up-regulation of heparan sulfate proteoglycan binding|activation of heparan sulfate proteoglycan binding|up-regulation of heparin proteoglycan binding|up regulation of heparan sulfate proteoglycan binding|activation of heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_1905860 GO:1905861 biolink:BiologicalProcess intranuclear rod assembly The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod. go-plus.json intranuclear rod formation|intranuclear actin rod assembly|intranuclear actin rod formation http://purl.obolibrary.org/obo/GO_1905861 GO:1905851 biolink:BiologicalProcess negative regulation of backward locomotion Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion. go-plus.json down regulation of backward locomotion|downregulation of backward locomotion|down-regulation of backward locomotion|inhibition of backward locomotion http://purl.obolibrary.org/obo/GO_1905851 GO:1905852 biolink:BiologicalProcess positive regulation of backward locomotion Any process that activates or increases the frequency, rate or extent of backward locomotion. go-plus.json upregulation of backward locomotion|up regulation of backward locomotion|activation of backward locomotion|up-regulation of backward locomotion http://purl.obolibrary.org/obo/GO_1905852 GO:1905853 biolink:BiologicalProcess regulation of heparan sulfate binding Any process that modulates the frequency, rate or extent of heparan sulfate binding. go-plus.json http://purl.obolibrary.org/obo/GO_1905853 GO:1905854 biolink:BiologicalProcess negative regulation of heparan sulfate binding Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding. go-plus.json down-regulation of heparan sulfate binding|inhibition of heparan sulfate binding|down regulation of heparan sulfate binding|downregulation of heparan sulfate binding http://purl.obolibrary.org/obo/GO_1905854 GO:1905855 biolink:BiologicalProcess positive regulation of heparan sulfate binding Any process that activates or increases the frequency, rate or extent of heparan sulfate binding. go-plus.json up regulation of heparan sulfate binding|activation of heparan sulfate binding|up-regulation of heparan sulfate binding|upregulation of heparan sulfate binding http://purl.obolibrary.org/obo/GO_1905855 GO:1905856 biolink:BiologicalProcess negative regulation of pentose-phosphate shunt Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt. go-plus.json http://purl.obolibrary.org/obo/GO_1905856 GO:1905857 biolink:BiologicalProcess positive regulation of pentose-phosphate shunt Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt. go-plus.json http://purl.obolibrary.org/obo/GO_1905857 GO:1905858 biolink:BiologicalProcess regulation of heparan sulfate proteoglycan binding Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding. go-plus.json regulation of heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_1905858 GO:1905859 biolink:BiologicalProcess negative regulation of heparan sulfate proteoglycan binding Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding. go-plus.json down regulation of heparin proteoglycan binding|inhibition of heparin proteoglycan binding|down-regulation of heparan sulfate proteoglycan binding|negative regulation of heparin proteoglycan binding|down-regulation of heparin proteoglycan binding|downregulation of heparan sulfate proteoglycan binding|down regulation of heparan sulfate proteoglycan binding|inhibition of heparan sulfate proteoglycan binding|downregulation of heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_1905859 GO:0099629 biolink:CellularComponent postsynaptic specialization of symmetric synapse A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses. go-plus.json postsynaptic density of inhibitory synapse http://purl.obolibrary.org/obo/GO_0099629 goslim_synapse CHEBI:51374 biolink:ChemicalSubstance GABA agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_51374 GO:0051680 biolink:BiologicalProcess 6-alpha-maltosylglucose biosynthetic process The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose. go-plus.json isopanose biosynthetic process|isopanose biosynthesis http://purl.obolibrary.org/obo/GO_0051680 GO:0099627 biolink:BiologicalProcess neurotransmitter receptor cycle The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping). go-plus.json http://purl.obolibrary.org/obo/GO_0099627 GO:0099628 biolink:BiologicalProcess neurotransmitter receptor diffusion trapping The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099628 goslim_synapse GO:0051683 biolink:BiologicalProcess establishment of Golgi localization The directed movement of the Golgi to a specific location. go-plus.json establishment of Golgi body localization|establishment of Golgi localisation|establishment of Golgi apparatus localization http://purl.obolibrary.org/obo/GO_0051683 GO:0099625 biolink:BiologicalProcess ventricular cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0099625 GO:0051684 biolink:BiologicalProcess maintenance of Golgi location Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of Golgi body localization|maintenance of Golgi localization|maintenance of Golgi apparatus localization http://purl.obolibrary.org/obo/GO_0051684 CHEBI:51371 biolink:ChemicalSubstance muscle relaxant go-plus.json http://purl.obolibrary.org/obo/CHEBI_51371 GO:0099626 biolink:MolecularActivity voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels. go-plus.json voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0099626 goslim_synapse GO:0099623 biolink:BiologicalProcess regulation of cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte. go-plus.json regulation of cardiac muscle cell repolarization|heart repolarization|regulation of cardiomyocyte membrane repolarization http://purl.obolibrary.org/obo/GO_0099623 CHEBI:51372 biolink:ChemicalSubstance neuromuscular agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_51372 GO:0051681 biolink:BiologicalProcess 6-alpha-maltosylglucose catabolic process The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose. go-plus.json isopanose catabolism|isopanose catabolic process http://purl.obolibrary.org/obo/GO_0051681 CHEBI:51373 biolink:ChemicalSubstance GABA agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_51373 GO:0051682 biolink:BiologicalProcess galactomannan catabolic process The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units. go-plus.json http://purl.obolibrary.org/obo/GO_0051682 GO:0099624 biolink:BiologicalProcess atrial cardiac muscle cell membrane repolarization The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0099624 GO:0051698 biolink:MolecularActivity saccharopine oxidase activity Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2. go-plus.json SAX activity http://purl.obolibrary.org/obo/GO_0051698 GO:0002643 biolink:BiologicalProcess regulation of tolerance induction Any process that modulates the frequency, rate, or extent of tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0002643 GO:0002644 biolink:BiologicalProcess negative regulation of tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction. go-plus.json inhibition of tolerance induction|down regulation of tolerance induction|downregulation of tolerance induction|down-regulation of tolerance induction http://purl.obolibrary.org/obo/GO_0002644 GO:0051699 biolink:MolecularActivity proline oxidase activity Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2. RHEA:26124|MetaCyc:RXN-821 go-plus.json http://purl.obolibrary.org/obo/GO_0051699 GO:0051696 biolink:BiologicalProcess pointed-end actin filament uncapping The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. go-plus.json minus-end actin filament uncapping|minus end F-actin uncapping|pointed end F-actin uncapping|pointed end actin filament uncapping|minus end actin filament uncapping|minus-end F-actin uncapping|pointed-end F-actin uncapping http://purl.obolibrary.org/obo/GO_0051696 GO:0002645 biolink:BiologicalProcess positive regulation of tolerance induction Any process that activates or increases the frequency, rate, or extent of tolerance induction. go-plus.json up-regulation of tolerance induction|upregulation of tolerance induction|up regulation of tolerance induction|activation of tolerance induction|stimulation of tolerance induction http://purl.obolibrary.org/obo/GO_0002645 GO:0051697 biolink:BiologicalProcess protein delipidation The breakage of covalent bonds to detach lipid groups from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0051697 GO:0002646 biolink:BiologicalProcess regulation of central tolerance induction Any process that modulates the frequency, rate, or extent of central tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0002646 CHEBI:145742 biolink:ChemicalSubstance (Z)-3-amino-2-methylacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145742 GO:0002640 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002640 GO:0002641 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002641 GO:0002642 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002642 GO:0061020 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061020 GO:1905870 biolink:BiologicalProcess positive regulation of 3'-UTR-mediated mRNA stabilization Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. go-plus.json up regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-UTR-mediated mRNA stabilization|positive regulation of 3'-untranslated region-mediated mRNA stabilization|up regulation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-UTR-mediated mRNA stabilization|upregulation of 3'-untranslated region-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_1905870 GO:0061021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061021 GO:1905871 biolink:BiologicalProcess regulation of protein localization to cell leading edge Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. go-plus.json regulation of protein localisation in cell leading edge|regulation of protein localisation to cell leading edge|regulation of protein localization in cell leading edge http://purl.obolibrary.org/obo/GO_1905871 GO:0061022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061022 GO:1905872 biolink:BiologicalProcess negative regulation of protein localization to cell leading edge Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. go-plus.json downregulation of protein localization in cell leading edge|inhibition of protein localisation to cell leading edge|down regulation of protein localisation in cell leading edge|down regulation of protein localization to cell leading edge|downregulation of protein localisation in cell leading edge|negative regulation of protein localization in cell leading edge|down-regulation of protein localization in cell leading edge|downregulation of protein localization to cell leading edge|down regulation of protein localisation to cell leading edge|inhibition of protein localization in cell leading edge|down-regulation of protein localisation in cell leading edge|negative regulation of protein localisation in cell leading edge|downregulation of protein localisation to cell leading edge|down-regulation of protein localization to cell leading edge|inhibition of protein localisation in cell leading edge|inhibition of protein localization to cell leading edge|negative regulation of protein localisation to cell leading edge|down-regulation of protein localisation to cell leading edge|down regulation of protein localization in cell leading edge http://purl.obolibrary.org/obo/GO_1905872 GO:0061023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061023 GO:0061024 biolink:BiologicalProcess membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. go-plus.json cellular membrane organisation|cellular membrane organization|membrane organisation|membrane organization and biogenesis|single-organism membrane organization http://purl.obolibrary.org/obo/GO_0061024 goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl GO:1905862 biolink:CellularComponent ferroxidase complex A protein complex which is capable of ferroxidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905862 GO:1905863 biolink:BiologicalProcess obsolete invadopodium organization OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an invadopodium. go-plus.json http://purl.obolibrary.org/obo/GO_1905863 GO:0061025 biolink:BiologicalProcess membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane. Wikipedia:Lipid_bilayer_fusion go-plus.json single-organism membrane fusion|cellular membrane fusion http://purl.obolibrary.org/obo/GO_0061025 goslim_yeast GO:1905864 biolink:BiologicalProcess regulation of Atg1/ULK1 kinase complex assembly Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. go-plus.json regulation of ATG1 kinase complex assembly|regulation of ATG1/ULK1 signaling complex assembly|regulation of Atg1p signalling complex formation|regulation of ATG1-ATG13 complex assembly|regulation of ULK1-ATG13-FIP200 complex assembly|regulation of ATG1-ATG13 complex formation|regulation of ULK1-ATG13-FIP200 complex formation|regulation of Atg1p signalling complex assembly|regulation of ATG1/ULK1 signaling complex formation|regulation of ATG1 kinase complex formation|regulation of ULK1-ATG13-RB1CC1 complex assembly|regulation of ULK1 signaling complex assembly|regulation of ULK1 signaling complex formation|regulation of ATG1/ULK1 kinase complex formation|regulation of ULK1-ATG13-RB1CC1 complex formation http://purl.obolibrary.org/obo/GO_1905864 GO:0061026 biolink:BiologicalProcess cardiac muscle tissue regeneration The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. go-plus.json http://purl.obolibrary.org/obo/GO_0061026 GO:1905865 biolink:BiologicalProcess negative regulation of Atg1/ULK1 kinase complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. go-plus.json downregulation of ULK1-ATG13-RB1CC1 complex formation|downregulation of ATG1/ULK1 signaling complex assembly|inhibition of ATG1 kinase complex formation|down regulation of ATG1 kinase complex assembly|down-regulation of ULK1 signaling complex assembly|downregulation of Atg1p signalling complex formation|negative regulation of ULK1 signaling complex assembly|inhibition of ATG1 kinase complex assembly|down regulation of ATG1-ATG13 complex assembly|downregulation of ULK1-ATG13-FIP200 complex assembly|down regulation of ATG1/ULK1 signaling complex assembly|down-regulation of ULK1-ATG13-RB1CC1 complex assembly|down regulation of Atg1p signalling complex formation|negative regulation of ULK1-ATG13-RB1CC1 complex assembly|inhibition of ATG1/ULK1 kinase complex assembly|down regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ATG1-ATG13 complex formation|inhibition of ATG1/ULK1 signaling complex assembly|downregulation of ATG1-ATG13 complex assembly|down regulation of ULK1-ATG13-FIP200 complex assembly|inhibition of Atg1p signalling complex formation|down-regulation of ULK1-ATG13-RB1CC1 complex formation|inhibition of ULK1 signaling complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of Atg1p signalling complex assembly|down regulation of ATG1/ULK1 signaling complex formation|inhibition of ULK1-ATG13-FIP200 complex assembly|down regulation of ATG1-ATG13 complex formation|downregulation of ULK1-ATG13-FIP200 complex formation|down-regulation of ULK1 signaling complex formation|inhibition of ATG1-ATG13 complex formation|down regulation of ATG1 kinase complex formation|downregulation of Atg1p signalling complex assembly|negative regulation of ULK1 signaling complex formation|downregulation of ATG1/ULK1 signaling complex formation|downregulation of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ATG1/ULK1 kinase complex formation|inhibition of ULK1-ATG13-RB1CC1 complex formation|negative regulation of ATG1/ULK1 kinase complex formation|negative regulation of ATG1-ATG13 complex assembly|downregulation of ATG1 kinase complex formation|down-regulation of ATG1-ATG13 complex assembly|down regulation of ATG1/ULK1 kinase complex assembly|down regulation of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ULK1-ATG13-FIP200 complex formation|negative regulation of ULK1-ATG13-FIP200 complex formation|down regulation of ULK1 signaling complex assembly|inhibition of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ATG1 kinase complex assembly|negative regulation of ATG1 kinase complex assembly|negative regulation of Atg1p signalling complex assembly|downregulation of ULK1 signaling complex formation|downregulation of ATG1/ULK1 kinase complex assembly|down-regulation of Atg1p signalling complex assembly|negative regulation of ATG1/ULK1 signaling complex formation|down-regulation of ATG1/ULK1 signaling complex formation|negative regulation of ATG1/ULK1 signaling complex assembly|down-regulation of ATG1/ULK1 signaling complex assembly|inhibition of ATG1-ATG13 complex assembly|down-regulation of Atg1p signalling complex formation|downregulation of ULK1 signaling complex assembly|negative regulation of Atg1p signalling complex formation|downregulation of ATG1/ULK1 kinase complex formation|down regulation of ULK1 signaling complex formation|down-regulation of ATG1 kinase complex formation|negative regulation of ATG1 kinase complex formation|down-regulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ULK1-ATG13-FIP200 complex assembly|inhibition of ULK1-ATG13-FIP200 complex formation|inhibition of ULK1 signaling complex formation|down regulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of ATG1/ULK1 kinase complex formation|inhibition of Atg1p signalling complex assembly|downregulation of ATG1 kinase complex assembly|down-regulation of ATG1-ATG13 complex formation|negative regulation of ATG1-ATG13 complex formation|inhibition of ATG1/ULK1 signaling complex formation|inhibition of ATG1/ULK1 kinase complex formation|down-regulation of ATG1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_1905865 GO:0061027 biolink:BiologicalProcess umbilical cord development The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0061027 GO:1905866 biolink:BiologicalProcess positive regulation of Atg1/ULK1 kinase complex assembly Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. go-plus.json upregulation of ATG1/ULK1 kinase complex formation|activation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-FIP200 complex assembly|up-regulation of ATG1 kinase complex formation|positive regulation of ATG1-ATG13 complex formation|up regulation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ULK1-ATG13-FIP200 complex formation|up regulation of ATG1-ATG13 complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex formation|activation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ATG1 kinase complex assembly|up-regulation of ATG1/ULK1 kinase complex assembly|upregulation of Atg1p signalling complex assembly|up-regulation of ULK1 signaling complex formation|upregulation of ATG1/ULK1 signaling complex formation|activation of ULK1 signaling complex formation|upregulation of ATG1/ULK1 signaling complex assembly|up-regulation of ATG1/ULK1 kinase complex formation|up-regulation of ULK1 signaling complex assembly|upregulation of Atg1p signalling complex formation|activation of ATG1/ULK1 kinase complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ATG1 kinase complex formation|upregulation of ULK1-ATG13-FIP200 complex assembly|up regulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-RB1CC1 complex assembly|activation of ATG1-ATG13 complex assembly|positive regulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ATG1 kinase complex assembly|upregulation of ATG1-ATG13 complex formation|upregulation of ATG1/ULK1 kinase complex assembly|activation of ATG1 kinase complex assembly|up regulation of Atg1p signalling complex assembly|activation of ULK1-ATG13-FIP200 complex formation|positive regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex formation|up-regulation of ATG1/ULK1 signaling complex assembly|up regulation of ATG1/ULK1 signaling complex formation|positive regulation of ULK1 signaling complex formation|up-regulation of Atg1p signalling complex formation|activation of ATG1/ULK1 signaling complex assembly|positive regulation of Atg1p signalling complex assembly|upregulation of ULK1 signaling complex assembly|activation of Atg1p signalling complex assembly|up regulation of ULK1 signaling complex formation|activation of Atg1p signalling complex formation|positive regulation of ATG1/ULK1 signaling complex formation|activation of ATG1/ULK1 signaling complex formation|up regulation of ATG1 kinase complex formation|positive regulation of ATG1/ULK1 kinase complex formation|up-regulation of ULK1-ATG13-FIP200 complex assembly|activation of ULK1-ATG13-FIP200 complex assembly|positive regulation of ATG1 kinase complex formation|activation of ATG1 kinase complex formation|up regulation of ATG1/ULK1 kinase complex formation|upregulation of ULK1-ATG13-RB1CC1 complex assembly|up-regulation of ATG1-ATG13 complex formation|up-regulation of ATG1-ATG13 complex assembly|activation of ATG1-ATG13 complex formation|up regulation of ATG1/ULK1 kinase complex assembly|upregulation of ULK1-ATG13-RB1CC1 complex formation|positive regulation of ATG1 kinase complex assembly|activation of ATG1/ULK1 kinase complex assembly|up-regulation of ULK1-ATG13-FIP200 complex formation|up regulation of ATG1 kinase complex assembly|up regulation of ULK1 signaling complex assembly|positive regulation of ATG1/ULK1 signaling complex assembly|up-regulation of Atg1p signalling complex assembly|upregulation of ULK1 signaling complex formation|positive regulation of Atg1p signalling complex formation|up-regulation of ATG1/ULK1 signaling complex formation|activation of ULK1 signaling complex assembly|positive regulation of ULK1 signaling complex assembly|up regulation of ATG1/ULK1 signaling complex assembly|up regulation of Atg1p signalling complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex assembly|positive regulation of ULK1-ATG13-FIP200 complex assembly http://purl.obolibrary.org/obo/GO_1905866 GO:0061028 biolink:BiologicalProcess establishment of endothelial barrier The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. go-plus.json http://purl.obolibrary.org/obo/GO_0061028 GO:1905867 biolink:BiologicalProcess epididymis development The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. go-plus.json epididymus development http://purl.obolibrary.org/obo/GO_1905867 GO:0061029 biolink:BiologicalProcess eyelid development in camera-type eye The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. go-plus.json http://purl.obolibrary.org/obo/GO_0061029 GO:1905868 biolink:BiologicalProcess regulation of 3'-UTR-mediated mRNA stabilization Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. go-plus.json regulation of 3'-untranslated region-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_1905868 GO:1905869 biolink:BiologicalProcess negative regulation of 3'-UTR-mediated mRNA stabilization Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. go-plus.json inhibition of 3'-UTR-mediated mRNA stabilization|negative regulation of 3'-untranslated region-mediated mRNA stabilization|down-regulation of 3'-untranslated region-mediated mRNA stabilization|downregulation of 3'-untranslated region-mediated mRNA stabilization|down regulation of 3'-untranslated region-mediated mRNA stabilization|inhibition of 3'-untranslated region-mediated mRNA stabilization|down-regulation of 3'-UTR-mediated mRNA stabilization|downregulation of 3'-UTR-mediated mRNA stabilization|down regulation of 3'-UTR-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_1905869 GO:0051690 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051690 CHEBI:145747 biolink:ChemicalSubstance phosphatidylethanolamine 42:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145747 GO:0051691 biolink:BiologicalProcess cellular oligosaccharide metabolic process The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells. go-plus.json cellular oligosaccharide metabolism http://purl.obolibrary.org/obo/GO_0051691 CHEBI:145748 biolink:ChemicalSubstance PE(18:4_24:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145748 CHEBI:145749 biolink:ChemicalSubstance PE(24:1/18:4) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145749 GO:0051694 biolink:BiologicalProcess pointed-end actin filament capping The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. go-plus.json minus-end actin filament capping activity|pointed-end F-actin capping activity|minus-end F-actin capping activity|pointed-end actin capping activity http://purl.obolibrary.org/obo/GO_0051694 GO:0002647 biolink:BiologicalProcess negative regulation of central tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction. go-plus.json down-regulation of central tolerance induction|inhibition of central tolerance induction|down regulation of central tolerance induction|downregulation of central tolerance induction http://purl.obolibrary.org/obo/GO_0002647 GO:0002648 biolink:BiologicalProcess positive regulation of central tolerance induction Any process that activates or increases the frequency, rate, or extent of central tolerance induction. go-plus.json up regulation of central tolerance induction|activation of central tolerance induction|stimulation of central tolerance induction|up-regulation of central tolerance induction|upregulation of central tolerance induction http://purl.obolibrary.org/obo/GO_0002648 GO:0051695 biolink:BiologicalProcess actin filament uncapping The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. go-plus.json F-actin uncapping http://purl.obolibrary.org/obo/GO_0051695 GO:0051692 biolink:BiologicalProcess cellular oligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells. go-plus.json cellular oligosaccharide degradation|cellular oligosaccharide breakdown|cellular oligosaccharide catabolism http://purl.obolibrary.org/obo/GO_0051692 GO:0002649 biolink:BiologicalProcess regulation of tolerance induction to self antigen Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen. go-plus.json http://purl.obolibrary.org/obo/GO_0002649 GO:0051693 biolink:BiologicalProcess actin filament capping The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. go-plus.json actin capping activity|F-actin capping activity http://purl.obolibrary.org/obo/GO_0051693 GO:0002654 biolink:BiologicalProcess positive regulation of tolerance induction dependent upon immune response Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response. go-plus.json stimulation of tolerance induction dependent upon immune response|activation of tolerance induction dependent upon immune response|up-regulation of tolerance induction dependent upon immune response|positive regulation of immune response-dependent tolerance induction|up regulation of tolerance induction dependent upon immune response|upregulation of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002654 GO:0099600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099600 GO:0002655 biolink:BiologicalProcess regulation of tolerance induction to nonself antigen Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen. go-plus.json http://purl.obolibrary.org/obo/GO_0002655 GO:0002656 biolink:BiologicalProcess negative regulation of tolerance induction to nonself antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen. go-plus.json down-regulation of tolerance induction to nonself antigen|downregulation of tolerance induction to nonself antigen|down regulation of tolerance induction to nonself antigen|inhibition of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002656 GO:0002657 biolink:BiologicalProcess positive regulation of tolerance induction to nonself antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen. go-plus.json up-regulation of tolerance induction to nonself antigen|activation of tolerance induction to nonself antigen|up regulation of tolerance induction to nonself antigen|upregulation of tolerance induction to nonself antigen|stimulation of tolerance induction to nonself antigen http://purl.obolibrary.org/obo/GO_0002657 GO:0002650 biolink:BiologicalProcess negative regulation of tolerance induction to self antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen. go-plus.json down-regulation of tolerance induction to self antigen|inhibition of tolerance induction to self antigen|down regulation of tolerance induction to self antigen|downregulation of tolerance induction to self antigen http://purl.obolibrary.org/obo/GO_0002650 CHEBI:51356 biolink:ChemicalSubstance penicillinate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_51356 chebi_ph7_3 GO:0002651 biolink:BiologicalProcess positive regulation of tolerance induction to self antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen. go-plus.json up regulation of tolerance induction to self antigen|activation of tolerance induction to self antigen|stimulation of tolerance induction to self antigen|up-regulation of tolerance induction to self antigen|upregulation of tolerance induction to self antigen http://purl.obolibrary.org/obo/GO_0002651 GO:0002652 biolink:BiologicalProcess regulation of tolerance induction dependent upon immune response Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response. go-plus.json regulation of immune response-dependent tolerance induction http://purl.obolibrary.org/obo/GO_0002652 GO:0002653 biolink:BiologicalProcess negative regulation of tolerance induction dependent upon immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response. go-plus.json down-regulation of tolerance induction dependent upon immune response|downregulation of tolerance induction dependent upon immune response|negative regulation of immune response-dependent tolerance induction|down regulation of tolerance induction dependent upon immune response|inhibition of tolerance induction dependent upon immune response http://purl.obolibrary.org/obo/GO_0002653 CHEBI:145735 biolink:ChemicalSubstance (Z)-3-amino-2-methylacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_145735 chebi_ph7_3 GO:1905880 biolink:BiologicalProcess negative regulation of oogenesis Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. go-plus.json down-regulation of ovum development|negative regulation of ovum development|down regulation of oogenesis|downregulation of oogenesis|downregulation of ovum development|down regulation of ovum development|down-regulation of oogenesis|inhibition of ovum development|inhibition of oogenesis http://purl.obolibrary.org/obo/GO_1905880 GO:1905881 biolink:BiologicalProcess positive regulation of oogenesis Any process that activates or increases the frequency, rate or extent of oogenesis. go-plus.json upregulation of oogenesis|positive regulation of ovum development|up regulation of ovum development|up regulation of oogenesis|activation of oogenesis|upregulation of ovum development|up-regulation of oogenesis|up-regulation of ovum development|activation of ovum development http://purl.obolibrary.org/obo/GO_1905881 GO:0061010 biolink:BiologicalProcess gall bladder development The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile. go-plus.json http://purl.obolibrary.org/obo/GO_0061010 GO:1905882 biolink:CellularComponent obsolete other organism cell wall OBSOLETE. Any cell wall that is part of a other organism. go-plus.json http://purl.obolibrary.org/obo/GO_1905882 GO:0061011 biolink:BiologicalProcess hepatic duct development The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. go-plus.json http://purl.obolibrary.org/obo/GO_0061011 GO:0061012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061012 GO:1905883 biolink:BiologicalProcess regulation of triglyceride transport Any process that modulates the frequency, rate or extent of triglyceride transport. go-plus.json regulation of triacylglycerol transport http://purl.obolibrary.org/obo/GO_1905883 GO:1905873 biolink:BiologicalProcess positive regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. go-plus.json upregulation of protein localisation in cell leading edge|up-regulation of protein localisation to cell leading edge|up regulation of protein localization in cell leading edge|upregulation of protein localization to cell leading edge|positive regulation of protein localization in cell leading edge|activation of protein localization in cell leading edge|up regulation of protein localisation in cell leading edge|upregulation of protein localisation to cell leading edge|positive regulation of protein localisation in cell leading edge|activation of protein localisation in cell leading edge|up regulation of protein localization to cell leading edge|activation of protein localization to cell leading edge|up-regulation of protein localization in cell leading edge|up regulation of protein localisation to cell leading edge|positive regulation of protein localisation to cell leading edge|activation of protein localisation to cell leading edge|up-regulation of protein localisation in cell leading edge|upregulation of protein localization in cell leading edge|up-regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1905873 GO:0061013 biolink:BiologicalProcess regulation of mRNA catabolic process Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. go-plus.json regulation of mRNA decay http://purl.obolibrary.org/obo/GO_0061013 GO:1905874 biolink:BiologicalProcess regulation of postsynaptic density organization Any process that modulates the frequency, rate or extent of postsynaptic density organization. go-plus.json regulation of postsynaptic density organisation|regulation of post synaptic density organization|regulation of PSD organization|regulation of post-synaptic density organization http://purl.obolibrary.org/obo/GO_1905874 GO:0061014 biolink:BiologicalProcess positive regulation of mRNA catabolic process Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. go-plus.json positive regulation of mRNA decay http://purl.obolibrary.org/obo/GO_0061014 GO:1905875 biolink:BiologicalProcess negative regulation of postsynaptic density organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization. go-plus.json negative regulation of PSD organization|down-regulation of PSD organization|inhibition of postsynaptic density organization|down regulation of postsynaptic density organisation|downregulation of post synaptic density organization|downregulation of PSD organization|downregulation of postsynaptic density organisation|negative regulation of post-synaptic density organization|down-regulation of post-synaptic density organization|down regulation of post synaptic density organization|down regulation of PSD organization|inhibition of post synaptic density organization|down regulation of postsynaptic density organization|inhibition of PSD organization|downregulation of postsynaptic density organization|down-regulation of postsynaptic density organisation|negative regulation of postsynaptic density organisation|downregulation of post-synaptic density organization|down regulation of post-synaptic density organization|inhibition of post-synaptic density organization|inhibition of postsynaptic density organisation|down-regulation of postsynaptic density organization|down-regulation of post synaptic density organization|negative regulation of post synaptic density organization http://purl.obolibrary.org/obo/GO_1905875 GO:0061015 biolink:BiologicalProcess snRNA import into nucleus The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0061015 GO:1905876 biolink:BiologicalProcess positive regulation of postsynaptic density organization Any process that activates or increases the frequency, rate or extent of postsynaptic density organization. go-plus.json up-regulation of postsynaptic density organization|positive regulation of post synaptic density organization|upregulation of postsynaptic density organisation|positive regulation of PSD organization|up-regulation of post-synaptic density organization|activation of post-synaptic density organization|up regulation of post synaptic density organization|up regulation of PSD organization|upregulation of postsynaptic density organization|up regulation of postsynaptic density organisation|activation of postsynaptic density organisation|upregulation of post synaptic density organization|positive regulation of postsynaptic density organisation|positive regulation of post-synaptic density organization|upregulation of PSD organization|up regulation of post-synaptic density organization|up regulation of postsynaptic density organization|activation of postsynaptic density organization|up-regulation of post synaptic density organization|activation of post synaptic density organization|activation of PSD organization|up-regulation of PSD organization|up-regulation of postsynaptic density organisation|upregulation of post-synaptic density organization http://purl.obolibrary.org/obo/GO_1905876 GO:0061016 biolink:BiologicalProcess snRNA localization to Cajal body The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body. go-plus.json http://purl.obolibrary.org/obo/GO_0061016 GO:0061017 biolink:BiologicalProcess hepatoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0061017 GO:1905877 biolink:BiologicalProcess obsolete invadopodium assembly OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form an invadopodium. go-plus.json invadopodium formation http://purl.obolibrary.org/obo/GO_1905877 GO:0061018 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061018 GO:1905878 biolink:BiologicalProcess obsolete invadopodium disassembly OBSOLETE. The disaggregation of an invadopodium into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_1905878 OBO:go/extensions/ro_pending#results_in_connection_of biolink:OntologyClass obsolete results_in_connection_of go-plus.json http://purl.obolibrary.org/obo/go/extensions/ro_pending#results_in_connection_of GO:0061019 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061019 GO:0099609 biolink:MolecularActivity microtubule lateral binding Binding to the side of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0099609 GO:1905879 biolink:BiologicalProcess regulation of oogenesis Any process that modulates the frequency, rate or extent of oogenesis. go-plus.json regulation of ovum development http://purl.obolibrary.org/obo/GO_1905879 GO:0099607 biolink:BiologicalProcess lateral attachment of mitotic spindle microtubules to kinetochore The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate). go-plus.json http://purl.obolibrary.org/obo/GO_0099607 GO:0099608 biolink:BiologicalProcess regulation of action potential firing pattern Any process that regulates the temporal pattern of a sequence of action potentials in a neuron. go-plus.json spike train sculpting http://purl.obolibrary.org/obo/GO_0099608 CHEBI:51353 biolink:ChemicalSubstance N-carbamoyl-L-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51353 GO:0099605 biolink:BiologicalProcess regulation of action potential firing rate Any process that regulates the frequency of action potentials in a spike train. go-plus.json http://purl.obolibrary.org/obo/GO_0099605 CHEBI:51354 biolink:ChemicalSubstance benzylpenicillin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_51354 chebi_ph7_3 GO:0099606 biolink:BiologicalProcess microtubule plus-end directed mitotic chromosome migration The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression. go-plus.json plus-end directed chromosome gliding http://purl.obolibrary.org/obo/GO_0099606 GO:0099603 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099603 GO:0002658 biolink:BiologicalProcess regulation of peripheral tolerance induction Any process that modulates the frequency, rate, or extent of peripheral tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0002658 GO:0002659 biolink:BiologicalProcess negative regulation of peripheral tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction. go-plus.json inhibition of peripheral tolerance induction|down-regulation of peripheral tolerance induction|downregulation of peripheral tolerance induction|down regulation of peripheral tolerance induction http://purl.obolibrary.org/obo/GO_0002659 GO:0099604 biolink:MolecularActivity ligand-gated calcium channel activity Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0099604 GO:0099601 biolink:BiologicalProcess regulation of neurotransmitter receptor activity Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0099601 goslim_synapse GO:0099602 biolink:MolecularActivity neurotransmitter receptor regulator activity A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing. go-plus.json http://purl.obolibrary.org/obo/GO_0099602 GO:0036080 biolink:MolecularActivity purine nucleotide-sugar transmembrane transporter activity Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0036080 GO:0036081 biolink:MolecularActivity extracellular ammonia-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts. go-plus.json ionotropic ammonia receptor activity http://purl.obolibrary.org/obo/GO_0036081 GO:0036079 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036079 CHEBI:90955 biolink:ChemicalSubstance bacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90955 chebi_ph7_3 CHEBI:90956 biolink:ChemicalSubstance 2-exo-hydroxy-1,4-cineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_90956 chebi_ph7_3 GO:0036071 biolink:BiologicalProcess N-glycan fucosylation The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains. go-plus.json glycoprotein fucosylation http://purl.obolibrary.org/obo/GO_0036071 GO:0036072 biolink:BiologicalProcess direct ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0036072 GO:0036073 biolink:BiologicalProcess perichondral ossification Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_0036073 GO:0036074 biolink:BiologicalProcess metaplastic ossification Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division. go-plus.json metaplasia http://purl.obolibrary.org/obo/GO_0036074 GO:0036075 biolink:BiologicalProcess replacement ossification Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. go-plus.json indirect ossification http://purl.obolibrary.org/obo/GO_0036075 GO:0036076 biolink:BiologicalProcess ligamentous ossification Ossification wherein bone tissue forms within ligamentous tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0036076 GO:0036077 biolink:BiologicalProcess intratendonous ossification Ossification wherein bone tissue forms within tendonous tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0036077 GO:0036078 biolink:BiologicalProcess minus-end specific microtubule depolymerization The removal of tubulin heterodimers from the minus end of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0036078 CHEBI:75311 biolink:ChemicalSubstance methyl aklanonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75311 CHEBI:75327 biolink:ChemicalSubstance (8S,9S)-epoxy-(10R)-hydroxyicosa-(5Z,11Z,14Z)-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75327 chebi_ph7_3 CHEBI:75325 biolink:ChemicalSubstance cathartic go-plus.json http://purl.obolibrary.org/obo/CHEBI_75325 CHEBI:75326 biolink:ChemicalSubstance 8-oxo-ETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75326 chebi_ph7_3 UBERON:4300173 biolink:AnatomicalEntity pelvic fin bud A paired fin bud that develops into a pelvic fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300173 GO:0036070 biolink:BiologicalProcess light-independent bacteriochlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants. go-plus.json light-independent bacteriochlorophyll anabolism|light-independent bacteriochlorophyll biosynthesis|light-independent bacteriochlorophyll synthesis|light-independent bacteriochlorophyll formation|light independent bacteriochlorophyll biosynthetic process http://purl.obolibrary.org/obo/GO_0036070 UBERON:4300172 biolink:AnatomicalEntity pectoral fin bud A paired fin bud that develops into a pectoral fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300172 GO:0036068 biolink:BiologicalProcess light-independent chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light. go-plus.json light-independent chlorophyll anabolism|light-independent chlorophyll synthesis|light-independent chlorophyll formation|light-independent chlorophyll biosynthesis|light independent chlorophyll biosynthetic process http://purl.obolibrary.org/obo/GO_0036068 CHEBI:90946 biolink:ChemicalSubstance dTDP-4-(methylammonio)-2,3,4,6-tetradeoxy-alpha-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90946 chebi_ph7_3 CHEBI:90947 biolink:ChemicalSubstance dTDP-alpha-D-forosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90947 chebi_ph7_3 GO:0036069 biolink:BiologicalProcess light-dependent bacteriochlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants. go-plus.json light-dependent bacteriochlorophyll synthesis|light-dependent bacteriochlorophyll formation|light-dependent bacteriochlorophyll biosynthesis|light dependent bacteriochlorophyll biosynthetic process|light-dependent bacteriochlorophyll anabolism http://purl.obolibrary.org/obo/GO_0036069 CHEBI:90944 biolink:ChemicalSubstance dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90944 chebi_ph7_3 CHEBI:90945 biolink:ChemicalSubstance dTDP-4-ammonio-2,3,4,6-tetradeoxy-alpha-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90945 chebi_ph7_3 GO:0036060 biolink:BiologicalProcess slit diaphragm assembly The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration. go-plus.json http://purl.obolibrary.org/obo/GO_0036060 GO:0036061 biolink:BiologicalProcess muscle cell chemotaxis toward tendon cell The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells. go-plus.json muscle cell attraction|muscle cell chemotaxis towards tendon cell http://purl.obolibrary.org/obo/GO_0036061 CHEBI:75320 biolink:ChemicalSubstance 2-amino-5-chloro-cis,cis-muconic 6-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_75320 CHEBI:90940 biolink:ChemicalSubstance N-acetyl-L-phosphinothricin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90940 chebi_ph7_3 GO:0036062 biolink:CellularComponent presynaptic periactive zone A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development. go-plus.json pre-synaptic periactive zone|periactive zone http://purl.obolibrary.org/obo/GO_0036062 GO:0036063 biolink:CellularComponent acroblast A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle. go-plus.json spermatid acroblast http://purl.obolibrary.org/obo/GO_0036063 GO:0036064 biolink:CellularComponent ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. NIF_Subcellular:sao11978067 go-plus.json basal body|cilium basal body|cilial basal body|microtubule basal body|kinetosome http://purl.obolibrary.org/obo/GO_0036064 GO:0036065 biolink:BiologicalProcess fucosylation The covalent attachment of a fucosyl group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0036065 GO:0036066 biolink:BiologicalProcess protein O-linked fucosylation The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0036066 GO:0036067 biolink:BiologicalProcess light-dependent chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light. go-plus.json light-dependent chlorophyll synthesis|light-dependent chlorophyll formation|light-dependent chlorophyll biosynthesis|light dependent chlorophyll biosynthetic process|light-dependent chlorophyll anabolism http://purl.obolibrary.org/obo/GO_0036067 CHEBI:75322 biolink:ChemicalSubstance 8(S)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75322 chebi_ph7_3 GO:0036057 biolink:CellularComponent slit diaphragm A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration. go-plus.json http://purl.obolibrary.org/obo/GO_0036057 CHEBI:90979 biolink:ChemicalSubstance 5,20-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_90979 GO:0036058 biolink:BiologicalProcess filtration diaphragm assembly The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. go-plus.json http://purl.obolibrary.org/obo/GO_0036058 GO:0036059 biolink:BiologicalProcess nephrocyte diaphragm assembly The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0036059 CHEBI:90975 biolink:ChemicalSubstance O(4)-(N-acetyl-alpha-D-galactosaminyl)-trans-4-hydroxy-L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90975 chebi_ph7_3 CHEBI:90976 biolink:ChemicalSubstance 20-hydroxylipoxin A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90976 CHEBI:90978 biolink:ChemicalSubstance 20-hydroxylipoxin B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90978 GO:0036050 biolink:BiologicalProcess peptidyl-lysine succinylation The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine. RESID:AA0545 go-plus.json http://purl.obolibrary.org/obo/GO_0036050 GO:0036051 biolink:BiologicalProcess protein localization to trailing edge A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement. go-plus.json protein localisation to trailing edge http://purl.obolibrary.org/obo/GO_0036051 GO:0036052 biolink:BiologicalProcess protein localization to uropod A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell. go-plus.json protein localisation to uropod http://purl.obolibrary.org/obo/GO_0036052 GO:0036053 biolink:CellularComponent glomerular endothelium fenestra A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. go-plus.json GEnC fenestration|glomerular endothelial cell fenestration http://purl.obolibrary.org/obo/GO_0036053 GO:0036054 biolink:MolecularActivity protein-malonyllysine demalonylase activity Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide. go-plus.json peptidyl-malonyllysine demalonylase activity|protein malonyl lysine demalonylation activity|protein lysine demalonylation activity http://purl.obolibrary.org/obo/GO_0036054 GO:0036055 biolink:MolecularActivity protein-succinyllysine desuccinylase activity Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. RHEA:47668 go-plus.json peptidyl-succinyllysine desuccinylase activity|succinyl lysine desuccinylase activity|succinyllysine desuccinylase activity http://purl.obolibrary.org/obo/GO_0036055 CHEBI:75332 biolink:ChemicalSubstance nonadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75332 GO:0036056 biolink:CellularComponent filtration diaphragm A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. go-plus.json http://purl.obolibrary.org/obo/GO_0036056 CHEBI:90970 biolink:ChemicalSubstance 1alpha,23(S),25-trihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90970 chebi_ph7_3 CHEBI:75348 biolink:ChemicalSubstance (8E,10S,12Z,15Z)-10-hydroperoxyoctadec-8,12,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75348 chebi_ph7_3 GO:0036046 biolink:BiologicalProcess protein demalonylation The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0036046 CHEBI:90968 biolink:ChemicalSubstance 3-vinyl-bacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90968 chebi_ph7_3 GO:0036047 biolink:BiologicalProcess peptidyl-lysine demalonylation The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0036047 CHEBI:90969 biolink:ChemicalSubstance 7-hydroxybacteriochlorophyllide c(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90969 chebi_ph7_3 GO:0036048 biolink:BiologicalProcess protein desuccinylation The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0036048 GO:0036049 biolink:BiologicalProcess peptidyl-lysine desuccinylation The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0036049 CHEBI:90964 biolink:ChemicalSubstance 8,12-diethyl-3-vinylbacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90964 chebi_ph7_3 CHEBI:90965 biolink:ChemicalSubstance bacteriochlorophyllide c(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90965 chebi_ph7_3 CHEBI:90966 biolink:ChemicalSubstance 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90966 chebi_ph7_3 CHEBI:90967 biolink:ChemicalSubstance 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90967 chebi_ph7_3 CHEBI:75341 biolink:ChemicalSubstance (8E,10S)-10-hydroperoxy-8-octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75341 chebi_ph7_3 CHEBI:75342 biolink:ChemicalSubstance 1-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75342 chebi_ph7_3 GO:0036040 biolink:BiologicalProcess curcumin catabolic process The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin. go-plus.json (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolism|curcumin breakdown|diferuloylmethane catabolism|turmeric yellow catabolism|turmeric yellow degradation|diferuloylmethane degradation|turmeric yellow breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione degradation|diferuloylmethane breakdown|curcumin catabolism|turmeric yellow catabolic process|diferuloylmethane catabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolic process|curcumin degradation http://purl.obolibrary.org/obo/GO_0036040 GO:0036041 biolink:MolecularActivity long-chain fatty acid binding Binding to a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json long chain fatty acid binding http://purl.obolibrary.org/obo/GO_0036041 CHEBI:90963 biolink:ChemicalSubstance 3-vinylbacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90963 chebi_ph7_3 GO:0036042 biolink:MolecularActivity long-chain fatty acyl-CoA binding Binding to a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. go-plus.json long-chain fatty acyl-coenyme A binding http://purl.obolibrary.org/obo/GO_0036042 CHEBI:75346 biolink:ChemicalSubstance (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75346 chebi_ph7_3 GO:0036043 biolink:CellularComponent obsolete microspike OBSOLETE. A dynamic, actin-rich projection extending from the surface of a migrating animal cell. go-plus.json microspike http://purl.obolibrary.org/obo/GO_0036043 GO:0036044 biolink:BiologicalProcess obsolete protein malonylation OBSOLETE. The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group. go-plus.json protein malonylation http://purl.obolibrary.org/obo/GO_0036044 GO:0036045 biolink:BiologicalProcess obsolete peptidyl-lysine malonylation OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine. go-plus.json lysine malonylation|peptidyl-lysine malonylation http://purl.obolibrary.org/obo/GO_0036045 GO:0036035 biolink:BiologicalProcess osteoclast development The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. go-plus.json osteoclast cell development http://purl.obolibrary.org/obo/GO_0036035 GO:0036036 biolink:BiologicalProcess cardiac neural crest cell delamination The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0036036 CHEBI:131198 biolink:ChemicalSubstance (Z)-1,2-ethenediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_131198 chebi_ph7_3 GO:0036037 biolink:BiologicalProcess CD8-positive, alpha-beta T cell activation The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json http://purl.obolibrary.org/obo/GO_0036037 GO:0036038 biolink:CellularComponent MKS complex A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane. go-plus.json MKS module|tectonic complex|TCTN-B9D complex|B9 complex|tectonic-like complex http://purl.obolibrary.org/obo/GO_0036038 GO:0036039 biolink:BiologicalProcess curcumin metabolic process The chemical reactions and pathways involving the polyphenol, curcumin. go-plus.json diferuloylmethane metabolism|turmeric yellow metabolism|turmeric yellow metabolic process|diferuloylmethane metabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process|curcumin metabolism|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism http://purl.obolibrary.org/obo/GO_0036039 CHEBI:90996 biolink:ChemicalSubstance 12(S)-HpEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_90996 GO:0036030 biolink:CellularComponent protein C inhibitor-plasma kallikrein complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein. go-plus.json SERPINA5-plasma kallikrein complex|protein C inhibitor-KLKB1 complex|plasma serine protease inhibitor-plasma kallikrein complex|serpin A5-plasma kallikrein complex|PCI-plasma kallikrein complex http://purl.obolibrary.org/obo/GO_0036030 GO:0036031 biolink:BiologicalProcess recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript. go-plus.json recruitment of guanylyltransferase to RNA polymerase II holoenzyme complex|capping enzyme targeting to RNA polymerase II http://purl.obolibrary.org/obo/GO_0036031 CHEBI:75357 biolink:ChemicalSubstance 1-oleoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75357 GO:0036032 biolink:BiologicalProcess neural crest cell delamination The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube. go-plus.json neural crest cell emigration|neural crest cell segregation|neural crest cell individualization http://purl.obolibrary.org/obo/GO_0036032 CHEBI:90990 biolink:ChemicalSubstance 12,20-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_90990 GO:0036033 biolink:MolecularActivity mediator complex binding Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0036033 CHEBI:75354 biolink:ChemicalSubstance (11Z)-octadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75354 GO:0036034 biolink:BiologicalProcess mediator complex assembly The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0036034 CHEBI:90992 biolink:ChemicalSubstance 20-hydroxy-6-trans-leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90992 GO:0051600 biolink:BiologicalProcess regulation of endocytosis by exocyst localization Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. go-plus.json regulation of site selection of endocytosis|spatial regulation of endocytosis|relocation of endocytosis|regulation of endocytosis by exocyst localisation http://purl.obolibrary.org/obo/GO_0051600 GO:0051603 biolink:BiologicalProcess proteolysis involved in cellular protein catabolic process The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. go-plus.json peptidolysis during cellular protein catabolism|proteolysis during cellular protein catabolic process|proteolysis during cellular protein catabolism|peptidolysis during cellular protein catabolic process|peptidolysis involved in cellular protein catabolic process|peptidolysis involved in cellular protein catabolism http://purl.obolibrary.org/obo/GO_0051603 goslim_yeast GO:0051604 biolink:BiologicalProcess protein maturation Any process leading to the attainment of the full functional capacity of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0051604 goslim_yeast|goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl GO:0051601 biolink:BiologicalProcess exocyst localization Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. go-plus.json exocyst localisation|establishment and maintenance of exocyst localization http://purl.obolibrary.org/obo/GO_0051601 GO:0051602 biolink:BiologicalProcess response to electrical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. go-plus.json response to electricity http://purl.obolibrary.org/obo/GO_0051602 GO:0051607 biolink:BiologicalProcess defense response to virus Reactions triggered in response to the presence of a virus that act to protect the cell or organism. go-plus.json defence response to virus|defense response to viruses|antiviral response http://purl.obolibrary.org/obo/GO_0051607 GO:0051608 biolink:BiologicalProcess histamine transport The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json http://purl.obolibrary.org/obo/GO_0051608 GO:0051605 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051605 GO:0051606 biolink:BiologicalProcess detection of stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. go-plus.json perception of stimulus|stimulus sensing|stimulus detection http://purl.obolibrary.org/obo/GO_0051606 goslim_pir GO:0051609 biolink:BiologicalProcess inhibition of neurotransmitter uptake Any process that prevents the activation of the directed movement of a neurotransmitter into a cell. go-plus.json inhibition of neurotransmitter import http://purl.obolibrary.org/obo/GO_0051609 GO:0036024 biolink:CellularComponent protein C inhibitor-TMPRSS7 complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7. go-plus.json SERPINA5-TMPRSS7 complex|plasma serine protease inhibitor-TMPRSS7 complex|protein C inhibitor-matriptase-3 complex|serpin A5-TMPRSS7 complex|protein C inhibitor-transmembrane protease serine 7 complex|PCI-TMPRSS7 complex http://purl.obolibrary.org/obo/GO_0036024 GO:0036025 biolink:CellularComponent protein C inhibitor-TMPRSS11E complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E. go-plus.json plasma serine protease inhibitor-TMPRSS11E complex|serpin A5-TMPRSS11E complex|protein C inhibitor-transmembrane protease serine 11E complex|PCI-TMPRSS11E complex|SERPINA5-TMPRSS11E complex http://purl.obolibrary.org/obo/GO_0036025 GO:0036026 biolink:CellularComponent protein C inhibitor-PLAT complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator. go-plus.json serpin A5-PLAT complex|plasma serine protease inhibitor-PLAT complex|SERPINA5-PLAT complex|protein C inhibitor-tPA complex|protein C inhibitor-tissue-type plasminogen activator complex|PCI-PLAT complex http://purl.obolibrary.org/obo/GO_0036026 GO:0036027 biolink:CellularComponent protein C inhibitor-PLAU complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator. go-plus.json serpin A5-PLAU complex|protein C inhibitor-uPA complex|protein C inhibitor-urokinase-type plasminogen activator complex|plasma serine protease inhibitor-PLAU complex|protein C inhibitor-U-plasminogen activator complex|SERPINA5-PLAU complex|PCI-PLAU complex http://purl.obolibrary.org/obo/GO_0036027 GO:0036028 biolink:CellularComponent protein C inhibitor-thrombin complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin. go-plus.json protein C inhibitor-coagulation factor II complex|PCI-thrombin complex|serpin A5-thrombin complex|plasma serine protease inhibitor-thrombin complex|SERPINA5-thrombin complex|protein C inhibitor-F2 complex http://purl.obolibrary.org/obo/GO_0036028 CHEBI:90986 biolink:ChemicalSubstance (20S,24S)-dihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90986 chebi_ph7_3 GO:0036029 biolink:CellularComponent protein C inhibitor-KLK3 complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen. go-plus.json PCI-KLK3 complex|serpin A5-KLK3 complex|plasma serine protease inhibitor-KLK3 complex|protein C inhibitor-kallikrein-3 complex|SERPINA5-KLK3 complex|protein C inhibitor-prostate-specific antigen complex http://purl.obolibrary.org/obo/GO_0036029 CHEBI:75360 biolink:ChemicalSubstance (6Z)-octadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75360 CHEBI:90987 biolink:ChemicalSubstance 3-deoxy-D-glycero-beta-D-galacto-nonulosonate 9-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90987 chebi_ph7_3 CHEBI:90988 biolink:ChemicalSubstance 3-deoxy-D-glycero-beta-D-galacto-nonulosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90988 chebi_ph7_3 CHEBI:90989 biolink:ChemicalSubstance CMP-3-deoxy-D-glycero-beta-D-galacto-nonulosonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90989 chebi_ph7_3 CHEBI:90982 biolink:ChemicalSubstance 8,20-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_90982 CHEBI:75363 biolink:ChemicalSubstance 1-oleoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75363 CHEBI:90983 biolink:ChemicalSubstance (20S)-hydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90983 chebi_ph7_3 CHEBI:90984 biolink:ChemicalSubstance 20(S),25-dihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90984 chebi_ph7_3 CHEBI:90985 biolink:ChemicalSubstance (20S,24R)-dihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90985 chebi_ph7_3 GO:0036020 biolink:CellularComponent endolysosome membrane The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome. go-plus.json endolysosomal membrane http://purl.obolibrary.org/obo/GO_0036020 GO:0036021 biolink:CellularComponent endolysosome lumen The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome. go-plus.json endolysosomal lumen http://purl.obolibrary.org/obo/GO_0036021 GO:0036022 biolink:BiologicalProcess limb joint morphogenesis The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. go-plus.json knee morphogenesis|leg joint morphogenesis http://purl.obolibrary.org/obo/GO_0036022 CHEBI:90980 biolink:ChemicalSubstance 23(S),25-dihydroxy-24-oxovitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90980 chebi_ph7_3 GO:0036023 biolink:BiologicalProcess embryonic skeletal limb joint morphogenesis The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb. go-plus.json http://purl.obolibrary.org/obo/GO_0036023 GO:0051610 biolink:BiologicalProcess serotonin uptake The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. go-plus.json 5-hydroxytryptamine uptake|serotonin import|5HT uptake|5-HT uptake http://purl.obolibrary.org/obo/GO_0051610 GO:0051611 biolink:BiologicalProcess regulation of serotonin uptake Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell. go-plus.json regulation of serotonin import|regulation of 5HT uptake|regulation of 5-HT uptake|regulation of 5-hydroxytryptamine uptake http://purl.obolibrary.org/obo/GO_0051611 GO:0051614 biolink:BiologicalProcess inhibition of serotonin uptake Any process that prevents the activation of the directed movement of serotonin into a cell. go-plus.json inhibition of 5-hydroxytryptamine uptake|inhibition of 5-HT uptake|inhibition of serotonin import|inhibition of 5HT uptake http://purl.obolibrary.org/obo/GO_0051614 GO:0051615 biolink:BiologicalProcess histamine uptake The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json histamine import http://purl.obolibrary.org/obo/GO_0051615 UBERON:5001466 biolink:AnatomicalEntity pedal digit plus metapodial segment A subdivision of the autopod consisting of pedal digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. go-plus.json pedal digit|pedal digit digitopodial subdivision|pedal digit ray|pedal digit ( phalanges plus metapodial) plus soft tissue http://purl.obolibrary.org/obo/UBERON_5001466 GO:0051612 biolink:BiologicalProcess negative regulation of serotonin uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell. go-plus.json down-regulation of serotonin uptake|negative regulation of 5-hydroxytryptamine uptake|downregulation of serotonin uptake|down regulation of serotonin uptake|negative regulation of serotonin import|negative regulation of 5-HT uptake|negative regulation of 5HT uptake http://purl.obolibrary.org/obo/GO_0051612 GO:0051613 biolink:BiologicalProcess positive regulation of serotonin uptake Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell. go-plus.json up-regulation of serotonin uptake|activation of serotonin uptake|positive regulation of 5HT uptake|up regulation of serotonin uptake|positive regulation of 5-hydroxytryptamine uptake|upregulation of serotonin uptake|positive regulation of 5-HT uptake|positive regulation of serotonin import|stimulation of serotonin uptake http://purl.obolibrary.org/obo/GO_0051613 GO:0051618 biolink:BiologicalProcess positive regulation of histamine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell. go-plus.json upregulation of histamine uptake|positive regulation of histamine import|stimulation of histamine uptake|activation of histamine uptake|up-regulation of histamine uptake|up regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051618 GO:0051619 biolink:BiologicalProcess inhibition of histamine uptake Any process that prevents the activation of the directed movement of histamine into a cell. go-plus.json inhibition of histamine import http://purl.obolibrary.org/obo/GO_0051619 GO:0051616 biolink:BiologicalProcess regulation of histamine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell. go-plus.json regulation of histamine import http://purl.obolibrary.org/obo/GO_0051616 GO:0051617 biolink:BiologicalProcess negative regulation of histamine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell. go-plus.json negative regulation of histamine import|down-regulation of histamine uptake|downregulation of histamine uptake|down regulation of histamine uptake http://purl.obolibrary.org/obo/GO_0051617 GO:0036013 biolink:CellularComponent cyanelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0036013 GO:0036014 biolink:CellularComponent cyanelle intermembrane space The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer. go-plus.json cyanelle periplasm|cyanelle envelope lumen http://purl.obolibrary.org/obo/GO_0036014 GO:0036015 biolink:BiologicalProcess response to interleukin-3 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. go-plus.json response to IL-3 http://purl.obolibrary.org/obo/GO_0036015 GO:0036016 biolink:BiologicalProcess cellular response to interleukin-3 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. go-plus.json cellular response to IL-3 http://purl.obolibrary.org/obo/GO_0036016 GO:0036017 biolink:BiologicalProcess response to erythropoietin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis. go-plus.json http://purl.obolibrary.org/obo/GO_0036017 CHEBI:75370 biolink:ChemicalSubstance 2-(2,4-dichlorophenoxy)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75370 GO:0036018 biolink:BiologicalProcess cellular response to erythropoietin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036018 GO:0036019 biolink:CellularComponent endolysosome An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. go-plus.json http://purl.obolibrary.org/obo/GO_0036019 CHEBI:75374 biolink:ChemicalSubstance (S)-dichlorprop go-plus.json http://purl.obolibrary.org/obo/CHEBI_75374 CHEBI:131170 biolink:ChemicalSubstance (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[[(1S)-1-carboxy-2-phenylethyl]amino]-oxomethyl]-1-pyrrolidinyl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131170 CHEBI:75373 biolink:ChemicalSubstance (R)-dichlorprop go-plus.json http://purl.obolibrary.org/obo/CHEBI_75373 CHEBI:75378 biolink:ChemicalSubstance 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75378 GO:0036010 biolink:BiologicalProcess protein localization to endosome A process in which a protein is transported to, or maintained in, a location within an endosome. go-plus.json protein localization in endosome|protein localisation in endosome http://purl.obolibrary.org/obo/GO_0036010 GO:0036011 biolink:BiologicalProcess imaginal disc-derived leg segmentation Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint. go-plus.json http://purl.obolibrary.org/obo/GO_0036011 CHEBI:75376 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75376 GO:0036012 biolink:CellularComponent cyanelle inner membrane The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma. go-plus.json cyanelle inner envelope membrane http://purl.obolibrary.org/obo/GO_0036012 GO:0051621 biolink:BiologicalProcess regulation of norepinephrine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. go-plus.json regulation of noradrenaline uptake|regulation of levarterenol uptake|regulation of norepinephrine import http://purl.obolibrary.org/obo/GO_0051621 GO:0051622 biolink:BiologicalProcess negative regulation of norepinephrine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. go-plus.json negative regulation of levarterenol uptake|negative regulation of norepinephrine import|down regulation of norepinephrine uptake|downregulation of norepinephrine uptake|down-regulation of norepinephrine uptake|negative regulation of noradrenaline uptake http://purl.obolibrary.org/obo/GO_0051622 GO:0051620 biolink:BiologicalProcess norepinephrine uptake The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. go-plus.json norepinephrine reuptake|levarterenol uptake|noradrenaline reuptake|norepinephrine import|levarterenol reuptake|noradrenaline uptake http://purl.obolibrary.org/obo/GO_0051620 GO:0051625 biolink:BiologicalProcess epinephrine uptake The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. go-plus.json adrenaline uptake|epinephrine reuptake|adrenaline reuptake|epinephrine import http://purl.obolibrary.org/obo/GO_0051625 GO:0051626 biolink:BiologicalProcess regulation of epinephrine uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell. go-plus.json regulation of epinephrine import|regulation of adrenaline uptake http://purl.obolibrary.org/obo/GO_0051626 GO:0051623 biolink:BiologicalProcess positive regulation of norepinephrine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. go-plus.json positive regulation of norepinephrine import|upregulation of norepinephrine uptake|up regulation of norepinephrine uptake|activation of norepinephrine uptake|stimulation of norepinephrine uptake|up-regulation of norepinephrine uptake|positive regulation of levarterenol uptake|positive regulation of noradrenaline uptake http://purl.obolibrary.org/obo/GO_0051623 GO:0051624 biolink:BiologicalProcess inhibition of norepinephrine uptake Any process that prevents the activation of the directed movement of norepinephrine into a cell. go-plus.json inhibition of levarterenol uptake|inhibition of noradrenaline uptake|inhibition of norepinephrine import http://purl.obolibrary.org/obo/GO_0051624 GO:0051629 biolink:BiologicalProcess inhibition of epinephrine uptake Any process that prevents the activation of the directed movement of epinephrine into a cell. go-plus.json inhibition of epinephrine import|inhibition of adrenaline uptake http://purl.obolibrary.org/obo/GO_0051629 GO:0051627 biolink:BiologicalProcess negative regulation of epinephrine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell. go-plus.json negative regulation of adrenaline uptake|down-regulation of epinephrine uptake|downregulation of epinephrine uptake|down regulation of epinephrine uptake|negative regulation of epinephrine import http://purl.obolibrary.org/obo/GO_0051627 GO:0051628 biolink:BiologicalProcess positive regulation of epinephrine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell. go-plus.json positive regulation of epinephrine import|stimulation of epinephrine uptake|activation of epinephrine uptake|up-regulation of epinephrine uptake|positive regulation of adrenaline uptake|up regulation of epinephrine uptake|upregulation of epinephrine uptake http://purl.obolibrary.org/obo/GO_0051628 GO:0036002 biolink:MolecularActivity pre-mRNA binding Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule. go-plus.json protein-coding primary transcript binding http://purl.obolibrary.org/obo/GO_0036002 GO:0036003 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0036003 GO:0036004 biolink:MolecularActivity GAF domain binding Binding to a GAF protein domain. go-plus.json http://purl.obolibrary.org/obo/GO_0036004 GO:0036005 biolink:BiologicalProcess response to macrophage colony-stimulating factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. go-plus.json response to M-CSF|response to macrophage colony-stimulating factor|response to macrophage colony-stimulating factor stimulus http://purl.obolibrary.org/obo/GO_0036005 GO:0036006 biolink:BiologicalProcess cellular response to macrophage colony-stimulating factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. go-plus.json cellular response to M-CSF stimulus|cellular response to macrophage colony-stimulating factor http://purl.obolibrary.org/obo/GO_0036006 CHEBI:75381 biolink:ChemicalSubstance EC 1.11.1.* (peroxidases) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75381 GO:0036007 biolink:CellularComponent scintillon A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen. go-plus.json http://purl.obolibrary.org/obo/GO_0036007 GO:0036008 biolink:BiologicalProcess sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate. MetaCyc:SUCUTIL-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0036008 CHEBI:75380 biolink:ChemicalSubstance EC 1.11.1.6 (catalase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75380 GO:0036009 biolink:MolecularActivity protein-glutamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine. Reactome:R-HSA-6800138 go-plus.json http://purl.obolibrary.org/obo/GO_0036009 CHEBI:75385 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75385 GO:0036000 biolink:CellularComponent mucocyst A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0036000 GO:0036001 biolink:BiologicalProcess 'de novo' pyridoxal 5'-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components. MetaCyc:PYRIDOXSYN-PWY go-plus.json 'de novo' pyridoxal phosphate biosynthetic process|'de novo' pyridoxal 5'-phosphate biosynthesis|'de novo' PLP biosynthesis|'de novo' pyridoxal 5'-phosphate anabolism|'de novo' pyridoxal 5'-phosphate synthesis|'de novo' pyridoxal 5'-phosphate formation http://purl.obolibrary.org/obo/GO_0036001 CHEBI:26300 biolink:ChemicalSubstance propenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26300 GO:0120057 biolink:BiologicalProcess regulation of small intestinal transit Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. go-plus.json regulation of small intestine transit|regulation of small bowel transit http://purl.obolibrary.org/obo/GO_0120057 GO:0120058 biolink:BiologicalProcess positive regulation of small intestinal transit Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. go-plus.json positive regulation of small bowel transit|positive regulation of small intestine transit http://purl.obolibrary.org/obo/GO_0120058 GO:0120059 biolink:BiologicalProcess negative regulation of small intestinal transit Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. go-plus.json negative regulation of small bowel transit|negative regulation of small intestine transit http://purl.obolibrary.org/obo/GO_0120059 CHEBI:16977 biolink:ChemicalSubstance L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16977 CHEBI:16978 biolink:ChemicalSubstance leukotriene C4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_16978 CHEBI:41945 biolink:ChemicalSubstance 9-(2-deoxy-5-O-phosphono-beta-L-ribofuranosyl)guanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_41945 GO:0120053 biolink:MolecularActivity ribitol beta-1,4-xylosyltransferase activity Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R. go-plus.json http://purl.obolibrary.org/obo/GO_0120053 CHEBI:16975 biolink:ChemicalSubstance 1-acyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16975 GO:0120054 biolink:BiologicalProcess intestinal motility Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth). go-plus.json http://purl.obolibrary.org/obo/GO_0120054 CHEBI:16976 biolink:ChemicalSubstance hygromycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_16976 GO:0120055 biolink:BiologicalProcess small intestinal transit Migration of ingested material along the length of the small intestine. go-plus.json small bowel transit|small intestine transit http://purl.obolibrary.org/obo/GO_0120055 CHEBI:16973 biolink:ChemicalSubstance 11-deoxycorticosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16973 chebi_ph7_3 GO:0120056 biolink:BiologicalProcess large intestinal transit Migration of ingested material along the length of the large intestine. go-plus.json colon transit|colonic transit|large bowel transit|large intestine transit http://purl.obolibrary.org/obo/GO_0120056 CHEBI:41941 biolink:ChemicalSubstance (3,4-dihydroxyphenyl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41941 CHEBI:16974 biolink:ChemicalSubstance imidazol-4-ylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16974 CHEBI:16971 biolink:ChemicalSubstance benzene-1,2,4-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16971 chebi_ph7_3 CHEBI:16970 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16970 CHEBI:26313 biolink:ChemicalSubstance propynol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26313 CHEBI:16968 biolink:ChemicalSubstance 1,8-diazacyclotetradecane-2,9-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16968 chebi_ph7_3 GO:0120068 biolink:BiologicalProcess regulation of stomach fundus smooth muscle contraction Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0120068 GO:0120069 biolink:BiologicalProcess positive regulation of stomach fundus smooth muscle contraction Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0120069 CHEBI:16966 biolink:ChemicalSubstance heteroglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_16966 CHEBI:16967 biolink:ChemicalSubstance (Z)-5-oxohex-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16967 chebi_ph7_3 GO:0120064 biolink:BiologicalProcess stomach pylorus smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach. go-plus.json http://purl.obolibrary.org/obo/GO_0120064 CHEBI:16964 biolink:ChemicalSubstance 5-hydroxymethyluracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_16964 chebi_ph7_3 GO:0120065 biolink:BiologicalProcess pyloric antrum smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach. go-plus.json antrum smooth muscle contraction http://purl.obolibrary.org/obo/GO_0120065 CHEBI:16965 biolink:ChemicalSubstance 2,3-dihydrogossypetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16965 chebi_ph7_3 CHEBI:16962 biolink:ChemicalSubstance cortisone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16962 chebi_ph7_3 GO:0120066 biolink:BiologicalProcess pyloric canal smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter. go-plus.json http://purl.obolibrary.org/obo/GO_0120066 GO:0120067 biolink:BiologicalProcess pyloric sphincter smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum. go-plus.json http://purl.obolibrary.org/obo/GO_0120067 GO:0120060 biolink:BiologicalProcess regulation of gastric emptying Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go-plus.json regulation of small intestine emptying|regulation of small bowel emptying http://purl.obolibrary.org/obo/GO_0120060 CHEBI:16960 biolink:ChemicalSubstance ADP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16960 GO:0120061 biolink:BiologicalProcess negative regulation of gastric emptying Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go-plus.json http://purl.obolibrary.org/obo/GO_0120061 CHEBI:16961 biolink:ChemicalSubstance monoacylglycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16961 GO:0120062 biolink:BiologicalProcess positive regulation of gastric emptying Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go-plus.json http://purl.obolibrary.org/obo/GO_0120062 GO:0120063 biolink:BiologicalProcess stomach smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach. go-plus.json http://purl.obolibrary.org/obo/GO_0120063 GO:0120079 biolink:BiologicalProcess obsolete regulation of microfilament motor activity OBSOLETE. Any process that modulates the frequency, rate or extent of microfilament motor activity. go-plus.json regulation of actin-activated ATPase activity|regulation of actin-dependent ATPase activity|regulation of actin filament motor activity|regulation of myosin ATPase activity|regulation of actin-filament motor activity|regulation of muscle motor activity http://purl.obolibrary.org/obo/GO_0120079 CHEBI:16999 biolink:ChemicalSubstance 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16999 GO:0120075 biolink:BiologicalProcess positive regulation of endocardial cushion cell differentiation Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0120075 CHEBI:16997 biolink:ChemicalSubstance propane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16997 chebi_ph7_3 GO:0120076 biolink:BiologicalProcess negative regulation of endocardial cushion cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0120076 CHEBI:16998 biolink:ChemicalSubstance D-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16998 CHEBI:65932 biolink:ChemicalSubstance funalenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_65932 GO:0120077 biolink:BiologicalProcess angiogenic sprout fusion The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis. go-plus.json blood vessel anastomosis|angiogenic sprout fusion http://purl.obolibrary.org/obo/GO_0120077 CHEBI:16995 biolink:ChemicalSubstance oxalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16995 CHEBI:16996 biolink:ChemicalSubstance L-histidinol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16996 GO:0120078 biolink:BiologicalProcess cell adhesion involved in sprouting angiogenesis The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network. go-plus.json cell adhesion involved in vascular anastomosis|cell adhesion involved in blood vessel anastomosis http://purl.obolibrary.org/obo/GO_0120078 GO:0120071 biolink:BiologicalProcess regulation of pyloric antrum smooth muscle contraction Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0120071 CHEBI:16993 biolink:ChemicalSubstance 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16993 GO:0120072 biolink:BiologicalProcess positive regulation of pyloric antrum smooth muscle contraction Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0120072 CHEBI:16994 biolink:ChemicalSubstance 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16994 chebi_ph7_3 GO:0120073 biolink:BiologicalProcess negative regulation of pyloric antrum smooth muscle contraction Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0120073 CHEBI:16991 biolink:ChemicalSubstance deoxyribonucleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16991 GO:0120074 biolink:BiologicalProcess regulation of endocardial cushion cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell. go-plus.json http://purl.obolibrary.org/obo/GO_0120074 CHEBI:16992 biolink:ChemicalSubstance 2-hydroxy-3-oxopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16992 CHEBI:16990 biolink:ChemicalSubstance bilirubin IXalpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_16990 CHEBI:41929 biolink:ChemicalSubstance 2-deoxy-5-O-phosphono-beta-L-ribofuranosylcytosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_41929 GO:0120070 biolink:BiologicalProcess negative regulation of stomach fundus smooth muscle contraction Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0120070 CHEBI:16988 biolink:ChemicalSubstance D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16988 CHEBI:16989 biolink:ChemicalSubstance 2-(carboxymethyl)-5-oxo-2,5-dihydro-3-furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16989 GO:0120086 biolink:MolecularActivity (3S)-(+)-asterisca-2(9),6-diene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene. go-plus.json asterisca-2(9),6-diene synthase activity http://purl.obolibrary.org/obo/GO_0120086 CHEBI:16987 biolink:ChemicalSubstance 1-piperideine-6-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16987 chebi_ph7_3 CHEBI:16984 biolink:ChemicalSubstance N-acetylimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16984 chebi_ph7_3 CHEBI:16985 biolink:ChemicalSubstance 5beta-androstane-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16985 chebi_ph7_3 GO:0120082 biolink:CellularComponent smooth endoplasmic reticulum cisterna A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0120082 CHEBI:16982 biolink:ChemicalSubstance (R,R)-butane-2,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16982 chebi_ph7_3 GO:0120083 biolink:CellularComponent rough endoplasmic reticulum cisterna A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0120083 GO:0120084 biolink:BiologicalProcess endothelial tip cell filopodium assembly The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout. go-plus.json http://purl.obolibrary.org/obo/GO_0120084 CHEBI:16980 biolink:ChemicalSubstance geranial go-plus.json http://purl.obolibrary.org/obo/CHEBI_16980 chebi_ph7_3 GO:0120085 biolink:BiologicalProcess transposon integration involved in RNA-mediated transposition Any transposon integration that contributes to a process of RNA-mediated transposition. go-plus.json retrotransposon integration http://purl.obolibrary.org/obo/GO_0120085 CHEBI:16981 biolink:ChemicalSubstance O-(3-O-D-galactosyl-N-acetyl-beta-D-galactosaminyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16981 CHEBI:41917 biolink:ChemicalSubstance 4-phospho-L-threonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41917 GO:0120080 biolink:BiologicalProcess obsolete negative regulation of microfilament motor activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity. go-plus.json negative regulation of actin filament motor activity|negative regulation of actin-filament motor activity|negative regulation of muscle motor activity|down regulation of actin-activated ATPase activity|inhibition of actin-dependent ATPase activity|negative regulation of myosin ATPase activity|down regulation of actin-dependent ATPase activity|negative regulation of actin-activated ATPase activity|inhibition of actin-activated ATPase activity|negative regulation of actin-dependent ATPase activity http://purl.obolibrary.org/obo/GO_0120080 GO:0120081 biolink:BiologicalProcess obsolete positive regulation of microfilament motor activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of microfilament motor activity. go-plus.json positive regulation of myosin ATPase activity|activation of actin-dependent ATPase activity|positive regulation of muscle motor activity|positive regulation of actin-filament motor activity|activation of actin-activated ATPase activity|upregulation of actin-dependent ATPase activity|positive regulation of actin-activated ATPase activity|positive regulation of actin-dependent ATPase activity|positive regulation of actin filament motor activity http://purl.obolibrary.org/obo/GO_0120081 GO:0120017 biolink:MolecularActivity ceramide transfer activity Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json ceramide carrier activity|intermembrane ceramide transfer activity|ceramide transporter activity http://purl.obolibrary.org/obo/GO_0120017 CHEBI:16939 biolink:ChemicalSubstance 3-amino-3-(4-hydroxyphenyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16939 CHEBI:90906 biolink:ChemicalSubstance protodeoxyviolaceinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90906 GO:0120018 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0120018 CHEBI:90907 biolink:ChemicalSubstance protodeoxyviolaceinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90907 chebi_ph7_3 GO:0120019 biolink:MolecularActivity phosphatidylcholine transfer activity Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json phosphatidylcholine carrier activity|intermembrane phosphatidylcholine transfer activity http://purl.obolibrary.org/obo/GO_0120019 CHEBI:16937 biolink:ChemicalSubstance 5,6-dihydroxy-3-methylquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16937 chebi_ph7_3 CHEBI:90909 biolink:ChemicalSubstance deoxyviolaceinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90909 CHEBI:16938 biolink:ChemicalSubstance 6-O-phosphono-D-glucono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16938 GO:0120013 biolink:MolecularActivity lipid transfer activity Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids. go-plus.json lipid carrier activity|intermembrane lipid transfer activity http://purl.obolibrary.org/obo/GO_0120013 CHEBI:16935 biolink:ChemicalSubstance L-rhamnofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16935 chebi_ph7_3 GO:0120014 biolink:MolecularActivity phospholipid transfer activity Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json intermembrane phospholipid transfer activity|phospholipid carrier activity http://purl.obolibrary.org/obo/GO_0120014 CHEBI:90915 biolink:ChemicalSubstance aurachin go-plus.json http://purl.obolibrary.org/obo/CHEBI_90915 CHEBI:16933 biolink:ChemicalSubstance ergosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16933 chebi_ph7_3 GO:0120015 biolink:MolecularActivity sterol transfer activity Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json sterol carrier activity|intermembrane sterol transfer activity http://purl.obolibrary.org/obo/GO_0120015 GO:0120016 biolink:MolecularActivity sphingolipid transfer activity Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json intermembrane sphingolipid transfer activity|sphingolipid carrier activity http://purl.obolibrary.org/obo/GO_0120016 CHEBI:16934 biolink:ChemicalSubstance 3-cyano-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16934 CHEBI:16931 biolink:ChemicalSubstance trans-cyclohexane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16931 chebi_ph7_3 GO:0120010 biolink:BiologicalProcess intermembrane phospholipid transfer The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0120010 CHEBI:90910 biolink:ChemicalSubstance deoxyviolaceinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90910 chebi_ph7_3 CHEBI:89929 biolink:ChemicalSubstance glycoursodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_89929 CHEBI:16932 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16932 GO:0120011 biolink:BiologicalProcess intermembrane sterol transfer The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). go-plus.json http://purl.obolibrary.org/obo/GO_0120011 GO:0120012 biolink:BiologicalProcess intermembrane sphingolipid transfer The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). go-plus.json http://purl.obolibrary.org/obo/GO_0120012 GO:0120028 biolink:BiologicalProcess negative regulation of osmosensory signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120028 GO:0120029 biolink:BiologicalProcess proton export across plasma membrane The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region. go-plus.json hydrogen ion export across plasma membrane|proton export across plasma membrane|proton export from cell|hydrogen ion export from cell http://purl.obolibrary.org/obo/GO_0120029 CHEBI:16929 biolink:ChemicalSubstance sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16929 CHEBI:16927 biolink:ChemicalSubstance L-saccharopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16927 CHEBI:16924 biolink:ChemicalSubstance 5-oxo-D-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16924 GO:0120024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0120024 CHEBI:90902 biolink:ChemicalSubstance 4-hydroxyprotoasukamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_90902 chebi_ph7_3 GO:0120025 biolink:CellularComponent plasma membrane bounded cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. go-plus.json http://purl.obolibrary.org/obo/GO_0120025 CHEBI:90903 biolink:ChemicalSubstance asperlicin E go-plus.json http://purl.obolibrary.org/obo/CHEBI_90903 chebi_ph7_3 CHEBI:16925 biolink:ChemicalSubstance 6-phospho-5-dehydro-2-deoxy-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16925 CHEBI:90904 biolink:ChemicalSubstance asperlicin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_90904 chebi_ph7_3 GO:0120026 biolink:CellularComponent host cell uropod A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively. go-plus.json host cell uropodium http://purl.obolibrary.org/obo/GO_0120026 CHEBI:16923 biolink:ChemicalSubstance N-formyl-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16923 chebi_ph7_3 GO:0120027 biolink:BiologicalProcess regulation of osmosensory signaling pathway Any process that modulates the frequency, rate or extent of osmosensory signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120027 GO:0120020 biolink:MolecularActivity cholesterol transfer activity Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Reactome:R-HSA-265443|Reactome:R-HSA-5682111|Reactome:R-HSA-265545|Reactome:R-HSA-1454928|Reactome:R-HSA-266082|Reactome:R-HSA-216723|Reactome:R-HSA-8951850 go-plus.json cholesterol carrier activity|intermembrane cholesterol transfer activity|cholesterol transporter activity http://purl.obolibrary.org/obo/GO_0120020 GO:0120021 biolink:MolecularActivity oxysterol transfer activity Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json oxysterol carrier activity|intermembrane oxysterol transfer activity http://purl.obolibrary.org/obo/GO_0120021 GO:0120022 biolink:MolecularActivity glucagon family peptide binding Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP). go-plus.json glucagon-like peptide binding|glucagon binding http://purl.obolibrary.org/obo/GO_0120022 CHEBI:90900 biolink:ChemicalSubstance violaceinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90900 chebi_ph7_3 GO:0120023 biolink:MolecularActivity somatostatin binding Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin. go-plus.json http://purl.obolibrary.org/obo/GO_0120023 CHEBI:90901 biolink:ChemicalSubstance protoasukamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_90901 chebi_ph7_3 GO:0120039 biolink:BiologicalProcess plasma membrane bounded cell projection morphogenesis The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0120039 CHEBI:16959 biolink:ChemicalSubstance albendazole S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16959 chebi_ph7_3 GO:0120035 biolink:BiologicalProcess regulation of plasma membrane bounded cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. go-plus.json http://purl.obolibrary.org/obo/GO_0120035 CHEBI:16957 biolink:ChemicalSubstance deacetoxyvindoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16957 GO:0120036 biolink:BiologicalProcess plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. go-plus.json http://purl.obolibrary.org/obo/GO_0120036 CHEBI:16958 biolink:ChemicalSubstance beta-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16958 CHEBI:16955 biolink:ChemicalSubstance GDP-4-dehydro-6-deoxy-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16955 GO:0120038 biolink:CellularComponent obsolete plasma membrane bounded cell projection part OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon. go-plus.json http://purl.obolibrary.org/obo/GO_0120038 GO:0120031 biolink:BiologicalProcess plasma membrane bounded cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. go-plus.json eupodium http://purl.obolibrary.org/obo/GO_0120031 CHEBI:16953 biolink:ChemicalSubstance N-acetyl-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16953 chebi_ph7_3 GO:0120032 biolink:BiologicalProcess regulation of plasma membrane bounded cell projection assembly Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0120032 CHEBI:16954 biolink:ChemicalSubstance vitexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16954 GO:0120033 biolink:BiologicalProcess negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0120033 GO:0120034 biolink:BiologicalProcess positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0120034 CHEBI:16952 biolink:ChemicalSubstance 5-hydroxymethyldeoxycytidylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16952 CHEBI:16950 biolink:ChemicalSubstance 2-dehydro-3-deoxy-L-fuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16950 GO:0120030 biolink:BiologicalProcess positive regulation of cilium beat frequency involved in ciliary motility Any process that activates or increases the frequency of cilium beating involved in ciliary motility. go-plus.json http://purl.obolibrary.org/obo/GO_0120030 CHEBI:75305 biolink:ChemicalSubstance glutamine hydroxamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75305 CHEBI:75306 biolink:ChemicalSubstance 2-heptyl-4-hydroxyquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_75306 chebi_ph7_3 CHEBI:75304 biolink:ChemicalSubstance 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75304 chebi_ph7_3 CHEBI:75309 biolink:ChemicalSubstance aklanonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75309 CHEBI:75308 biolink:ChemicalSubstance 19-oxotestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75308 chebi_ph7_3 CHEBI:90917 biolink:ChemicalSubstance A-type aurachin go-plus.json http://purl.obolibrary.org/obo/CHEBI_90917 CHEBI:90918 biolink:ChemicalSubstance C-type aurachin go-plus.json http://purl.obolibrary.org/obo/CHEBI_90918 GO:0120046 biolink:BiologicalProcess regulation of protein localization to medial cortical node Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node. go-plus.json http://purl.obolibrary.org/obo/GO_0120046 CHEBI:16946 biolink:ChemicalSubstance L-kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16946 CHEBI:16947 biolink:ChemicalSubstance citrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16947 chebi_ph7_3 GO:0120047 biolink:BiologicalProcess positive regulation of protein localization to medial cortical node Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node. go-plus.json http://purl.obolibrary.org/obo/GO_0120047 GO:0120048 biolink:MolecularActivity U6 snRNA (adenine-(43)-N(6))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0120048 CHEBI:16944 biolink:ChemicalSubstance L-2-amino-3-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16944 GO:0120049 biolink:BiologicalProcess snRNA (adenine-N6)-methylation The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0120049 CHEBI:16945 biolink:ChemicalSubstance scytalone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16945 chebi_ph7_3 GO:0120042 biolink:BiologicalProcess negative regulation of macrophage proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0120042 CHEBI:90920 biolink:ChemicalSubstance EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_90920 CHEBI:16942 biolink:ChemicalSubstance lipid X go-plus.json http://purl.obolibrary.org/obo/CHEBI_16942 GO:0120043 biolink:CellularComponent stereocilium shaft The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle. go-plus.json http://purl.obolibrary.org/obo/GO_0120043 CHEBI:90921 biolink:ChemicalSubstance EC 1.8.5.4 (sulfide:quinone reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_90921 CHEBI:16943 biolink:ChemicalSubstance (R)-2,4-dihydroxy-3-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16943 GO:0120044 biolink:CellularComponent stereocilium base The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium. go-plus.json stereocilium taper http://purl.obolibrary.org/obo/GO_0120044 GO:0120045 biolink:BiologicalProcess stereocilium maintenance The organization process that preserves a stereocilium in a stable functional or structural state. go-plus.json http://purl.obolibrary.org/obo/GO_0120045 CHEBI:16941 biolink:ChemicalSubstance cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16941 chebi_ph7_3 GO:0120040 biolink:BiologicalProcess regulation of macrophage proliferation Any process that modulates the frequency, rate or extent of macrophage proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0120040 GO:0120041 biolink:BiologicalProcess positive regulation of macrophage proliferation Any process that activates or increases the frequency, rate or extent of macrophage proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0120041 CHEBI:75301 biolink:ChemicalSubstance 1-palmitoyl-2-hexanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75301 chebi_ph7_3 CHEBI:75302 biolink:ChemicalSubstance 1-palmitoyl-2-capryloyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75302 chebi_ph7_3 CHEBI:75300 biolink:ChemicalSubstance 1-palmitoyl-2-decanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75300 chebi_ph7_3 GO:0002863 biolink:BiologicalProcess positive regulation of inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. go-plus.json stimulation of inflammatory response to antigenic stimulus|up-regulation of inflammatory response to antigenic stimulus|upregulation of inflammatory response to antigenic stimulus|up regulation of inflammatory response to antigenic stimulus|activation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002863 CHEBI:51349 biolink:ChemicalSubstance polyamine macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_51349 GO:0002864 biolink:BiologicalProcess regulation of acute inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002864 GO:0002865 biolink:BiologicalProcess negative regulation of acute inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. go-plus.json inhibition of acute inflammatory response to antigenic stimulus|down regulation of acute inflammatory response to antigenic stimulus|downregulation of acute inflammatory response to antigenic stimulus|down-regulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002865 GO:0002866 biolink:BiologicalProcess positive regulation of acute inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. go-plus.json up-regulation of acute inflammatory response to antigenic stimulus|upregulation of acute inflammatory response to antigenic stimulus|up regulation of acute inflammatory response to antigenic stimulus|activation of acute inflammatory response to antigenic stimulus|stimulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002866 CHEBI:26389 biolink:ChemicalSubstance purine deoxyribonucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26389 GO:0002860 biolink:BiologicalProcess positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. go-plus.json up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target|activation of natural killer cell mediated cytotoxicity directed against tumor cell target|up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002860 GO:0002861 biolink:BiologicalProcess regulation of inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002861 GO:0002862 biolink:BiologicalProcess negative regulation of inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. go-plus.json down-regulation of inflammatory response to antigenic stimulus|inhibition of inflammatory response to antigenic stimulus|down regulation of inflammatory response to antigenic stimulus|downregulation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002862 CHEBI:26385 biolink:ChemicalSubstance purine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26385 GO:0061160 biolink:BiologicalProcess regulation of establishment of bipolar cell polarity regulating cell shape Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061160 CHEBI:26386 biolink:ChemicalSubstance purine nucleobase go-plus.json http://purl.obolibrary.org/obo/CHEBI_26386 chebi_ph7_3 GO:0061161 biolink:BiologicalProcess positive regulation of establishment of bipolar cell polarity regulating cell shape Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061161 CHEBI:26387 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26387 CHEBI:26388 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26388 GO:0061162 biolink:BiologicalProcess establishment of monopolar cell polarity The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. go-plus.json http://purl.obolibrary.org/obo/GO_0061162 GO:0061163 biolink:BiologicalProcess endoplasmic reticulum polarization The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity. go-plus.json endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|ER polarization|endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site|transitional endoplasmic reticulum polarization at cell division site|ER localization involved in ER polarization at cell division site http://purl.obolibrary.org/obo/GO_0061163 CHEBI:26381 biolink:ChemicalSubstance p-menth-4(8)-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_26381 chebi_ph7_3 GO:0061164 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061164 GO:0061165 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061165 CHEBI:26384 biolink:ChemicalSubstance pullulans go-plus.json http://purl.obolibrary.org/obo/CHEBI_26384 GO:0061166 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061166 GO:0061167 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061167 GO:0061168 biolink:BiologicalProcess regulation of hair follicle placode formation Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go-plus.json http://purl.obolibrary.org/obo/GO_0061168 GO:0061169 biolink:BiologicalProcess positive regulation of hair placode formation Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go-plus.json http://purl.obolibrary.org/obo/GO_0061169 CHEBI:26390 biolink:ChemicalSubstance purine 2'-deoxyribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26390 CHEBI:26391 biolink:ChemicalSubstance purine nucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26391 UBERON:8410056 biolink:AnatomicalEntity capillary of anorectum A capillary that is part of the anorectum. go-plus.json blood vessel capillary of anorectum http://purl.obolibrary.org/obo/UBERON_8410056 CHEBI:51341 biolink:ChemicalSubstance pristanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_51341 UBERON:8410057 biolink:AnatomicalEntity capillary of colon A capillary that is part of the colon. go-plus.json blood vessel capillary of colon http://purl.obolibrary.org/obo/UBERON_8410057 GO:0002867 biolink:BiologicalProcess regulation of B cell deletion Any process that modulates the frequency, rate, or extent of B cell deletion. go-plus.json regulation of B-cell deletion|regulation of B lymphocyte deletion|regulation of B-lymphocyte deletion http://purl.obolibrary.org/obo/GO_0002867 GO:0002868 biolink:BiologicalProcess negative regulation of B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion. go-plus.json down-regulation of B cell deletion|inhibition of B cell deletion|negative regulation of B-lymphocyte deletion|negative regulation of B-cell deletion|down regulation of B cell deletion|downregulation of B cell deletion|negative regulation of B lymphocyte deletion http://purl.obolibrary.org/obo/GO_0002868 GO:0002869 biolink:BiologicalProcess positive regulation of B cell deletion Any process that activates or increases the frequency, rate, or extent of B cell deletion. go-plus.json stimulation of B cell deletion|positive regulation of B-lymphocyte deletion|up-regulation of B cell deletion|positive regulation of B-cell deletion|upregulation of B cell deletion|positive regulation of B lymphocyte deletion|up regulation of B cell deletion|activation of B cell deletion http://purl.obolibrary.org/obo/GO_0002869 CHEBI:51340 biolink:ChemicalSubstance pristanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51340 GO:0002874 biolink:BiologicalProcess regulation of chronic inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002874 CHEBI:51339 biolink:ChemicalSubstance adamantanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_51339 GO:0002875 biolink:BiologicalProcess negative regulation of chronic inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. go-plus.json downregulation of chronic inflammatory response to antigenic stimulus|down-regulation of chronic inflammatory response to antigenic stimulus|inhibition of chronic inflammatory response to antigenic stimulus|down regulation of chronic inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002875 GO:0002876 biolink:BiologicalProcess positive regulation of chronic inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. go-plus.json up regulation of chronic inflammatory response to antigenic stimulus|activation of chronic inflammatory response to antigenic stimulus|stimulation of chronic inflammatory response to antigenic stimulus|up-regulation of chronic inflammatory response to antigenic stimulus|upregulation of chronic inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002876 UBERON:8410050 biolink:AnatomicalEntity anorectum A subdivision of the digestive tract in humans that includes the rectum, the anal canal and the anus. go-plus.json anorectal canal http://purl.obolibrary.org/obo/UBERON_8410050 GO:0002877 biolink:BiologicalProcess regulation of acute inflammatory response to non-antigenic stimulus Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002877 UBERON:8410051 biolink:AnatomicalEntity lymphatic vessel of colon A lymphatic vessel located in the colon. go-plus.json http://purl.obolibrary.org/obo/UBERON_8410051 GO:0002870 biolink:BiologicalProcess T cell anergy Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction. go-plus.json T-lymphocyte anergy|T-cell anergy|T lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002870 CHEBI:51334 biolink:ChemicalSubstance SO-thioperoxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_51334 chebi_ph7_3 GO:0002871 biolink:BiologicalProcess regulation of natural killer cell tolerance induction Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction. go-plus.json regulation of NK cell tolerance induction http://purl.obolibrary.org/obo/GO_0002871 GO:0002872 biolink:BiologicalProcess negative regulation of natural killer cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction. go-plus.json down regulation of natural killer cell tolerance induction|downregulation of natural killer cell tolerance induction|negative regulation of NK cell tolerance induction|down-regulation of natural killer cell tolerance induction|inhibition of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002872 GO:0002873 biolink:BiologicalProcess positive regulation of natural killer cell tolerance induction Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction. go-plus.json positive regulation of NK cell tolerance induction|up regulation of natural killer cell tolerance induction|activation of natural killer cell tolerance induction|stimulation of natural killer cell tolerance induction|up-regulation of natural killer cell tolerance induction|upregulation of natural killer cell tolerance induction http://purl.obolibrary.org/obo/GO_0002873 CHEBI:51337 biolink:ChemicalSubstance organic sulfate salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_51337 CHEBI:26396 biolink:ChemicalSubstance purine ribonucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26396 CHEBI:26397 biolink:ChemicalSubstance purine ribonucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26397 GO:0061150 biolink:BiologicalProcess renal system segmentation The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis. go-plus.json urinary tract segmentation http://purl.obolibrary.org/obo/GO_0061150 CHEBI:26398 biolink:ChemicalSubstance purine ribonucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26398 GO:0061151 biolink:BiologicalProcess BMP signaling pathway involved in renal system segmentation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system. go-plus.json BMP signalling pathway involved in renal system segmentation http://purl.obolibrary.org/obo/GO_0061151 CHEBI:26399 biolink:ChemicalSubstance purine ribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_26399 chebi_ph7_3 GO:0061152 biolink:BiologicalProcess trachea submucosa development The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. go-plus.json http://purl.obolibrary.org/obo/GO_0061152 CHEBI:26392 biolink:ChemicalSubstance purine nucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26392 GO:0061153 biolink:BiologicalProcess trachea gland development The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. go-plus.json http://purl.obolibrary.org/obo/GO_0061153 CHEBI:26393 biolink:ChemicalSubstance purine nucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26393 GO:0061154 biolink:BiologicalProcess endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061154 CHEBI:26394 biolink:ChemicalSubstance purine nucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_26394 GO:0061155 biolink:BiologicalProcess pulmonary artery endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. go-plus.json http://purl.obolibrary.org/obo/GO_0061155 CHEBI:26395 biolink:ChemicalSubstance purine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26395 GO:0061156 biolink:BiologicalProcess pulmonary artery morphogenesis The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. go-plus.json http://purl.obolibrary.org/obo/GO_0061156 GO:0061157 biolink:BiologicalProcess mRNA destabilization Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. go-plus.json http://purl.obolibrary.org/obo/GO_0061157 GO:0061158 biolink:BiologicalProcess 3'-UTR-mediated mRNA destabilization An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0061158 GO:0061159 biolink:BiologicalProcess establishment of bipolar cell polarity involved in cell morphogenesis The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane. go-plus.json http://purl.obolibrary.org/obo/GO_0061159 CHEBI:9533 biolink:ChemicalSubstance thiamine(1+) monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_9533 CHEBI:9534 biolink:ChemicalSubstance thiamine(1+) triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_9534 CHEBI:51333 biolink:ChemicalSubstance sulfenic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_51333 UBERON:8410048 biolink:AnatomicalEntity venule of colon A venule located in the colon. go-plus.json http://purl.obolibrary.org/obo/UBERON_8410048 GO:0002878 biolink:BiologicalProcess negative regulation of acute inflammatory response to non-antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. go-plus.json down regulation of acute inflammatory response to non-antigenic stimulus|downregulation of acute inflammatory response to non-antigenic stimulus|down-regulation of acute inflammatory response to non-antigenic stimulus|inhibition of acute inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002878 GO:0002879 biolink:BiologicalProcess positive regulation of acute inflammatory response to non-antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. go-plus.json up regulation of acute inflammatory response to non-antigenic stimulus|activation of acute inflammatory response to non-antigenic stimulus|stimulation of acute inflammatory response to non-antigenic stimulus|up-regulation of acute inflammatory response to non-antigenic stimulus|upregulation of acute inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002879 CHEBI:9532 biolink:ChemicalSubstance thiamine(1+) diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_9532 GO:0002841 biolink:BiologicalProcess negative regulation of T cell mediated immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell. go-plus.json negative regulation of T-lymphocyte mediated immune response to tumor cell|negative regulation of T-cell mediated immune response to tumor cell|down regulation of T cell mediated immune response to tumor cell|downregulation of T cell mediated immune response to tumor cell|negative regulation of T lymphocyte mediated immune response to tumor cell|negative regulation of T cell mediated immune response to tumour cell|down-regulation of T cell mediated immune response to tumor cell|inhibition of T cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002841 GO:0002842 biolink:BiologicalProcess positive regulation of T cell mediated immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell. go-plus.json up-regulation of T cell mediated immune response to tumor cell|positive regulation of T-cell mediated immune response to tumor cell|upregulation of T cell mediated immune response to tumor cell|positive regulation of T lymphocyte mediated immune response to tumor cell|up regulation of T cell mediated immune response to tumor cell|activation of T cell mediated immune response to tumor cell|stimulation of T cell mediated immune response to tumor cell|positive regulation of T cell mediated immune response to tumour cell|positive regulation of T-lymphocyte mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002842 GO:0002843 biolink:BiologicalProcess regulation of tolerance induction to tumor cell Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell. go-plus.json regulation of tolerance induction to tumour cell http://purl.obolibrary.org/obo/GO_0002843 GO:0002844 biolink:BiologicalProcess negative regulation of tolerance induction to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell. go-plus.json downregulation of tolerance induction to tumor cell|negative regulation of tolerance induction to tumour cell|down-regulation of tolerance induction to tumor cell|inhibition of tolerance induction to tumor cell|down regulation of tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002844 UBERON:8410041 biolink:AnatomicalEntity venule of lymph node A venule that is part of a lymph node. go-plus.json lymph node venule http://purl.obolibrary.org/obo/UBERON_8410041 CHEBI:51323 biolink:ChemicalSubstance cinchona alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51323 UBERON:8410042 biolink:AnatomicalEntity arteriole of lymph node An arteriole that is part of a lymph node. go-plus.json lymph node arteriole http://purl.obolibrary.org/obo/UBERON_8410042 CHEBI:51324 biolink:ChemicalSubstance vinylarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51324 CHEBI:26369 biolink:ChemicalSubstance psoralens go-plus.json http://purl.obolibrary.org/obo/CHEBI_26369 UBERON:8410043 biolink:AnatomicalEntity bronchus submucosal gland A submucosal gland located in a bronchus. go-plus.json airway submucosal gland|bronchial submucosal gland|submucosal bronchial gland|submucosal bronchus gland http://purl.obolibrary.org/obo/UBERON_8410043 GO:0002840 biolink:BiologicalProcess regulation of T cell mediated immune response to tumor cell Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell. go-plus.json regulation of T cell mediated immune response to tumour cell|regulation of T lymphocyte mediated immune response to tumor cell|regulation of T-lymphocyte mediated immune response to tumor cell|regulation of T-cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002840 GO:0061180 biolink:BiologicalProcess mammary gland epithelium development The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. go-plus.json breast epithelium development http://purl.obolibrary.org/obo/GO_0061180 GO:0061181 biolink:BiologicalProcess regulation of chondrocyte development Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. go-plus.json http://purl.obolibrary.org/obo/GO_0061181 GO:0061182 biolink:BiologicalProcess negative regulation of chondrocyte development Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. go-plus.json http://purl.obolibrary.org/obo/GO_0061182 GO:0061183 biolink:BiologicalProcess regulation of dermatome development Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go-plus.json http://purl.obolibrary.org/obo/GO_0061183 GO:0061184 biolink:BiologicalProcess positive regulation of dermatome development Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go-plus.json http://purl.obolibrary.org/obo/GO_0061184 CHEBI:26366 biolink:ChemicalSubstance pseudouridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26366 GO:0061185 biolink:BiologicalProcess negative regulation of dermatome development Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. go-plus.json http://purl.obolibrary.org/obo/GO_0061185 GO:0061186 biolink:BiologicalProcess negative regulation of silent mating-type cassette heterochromatin assembly Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. go-plus.json negative regulation of chromatin silencing at silent mating-type cassette http://purl.obolibrary.org/obo/GO_0061186 CHEBI:26361 biolink:ChemicalSubstance protoporphyrins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26361 GO:0061187 biolink:BiologicalProcess regulation of ribosomal DNA heterochromatin assembly Any process that modulates the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin. go-plus.json regulation of chromatin silencing at rDNA http://purl.obolibrary.org/obo/GO_0061187 GO:0061188 biolink:BiologicalProcess negative regulation of ribosomal DNA heterochromatin assembly Any process that decreases the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin. go-plus.json negative regulation of chromatin silencing at rDNA http://purl.obolibrary.org/obo/GO_0061188 GO:0061189 biolink:BiologicalProcess positive regulation of sclerotome development Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. go-plus.json http://purl.obolibrary.org/obo/GO_0061189 GO:0002849 biolink:BiologicalProcess regulation of peripheral T cell tolerance induction Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0002849 UBERON:8410034 biolink:AnatomicalEntity lymph node artery An artery that enters the lymph node at the hilum and branches into smaller arterioles. go-plus.json hilar artery of lymph node|artery of lymph node http://purl.obolibrary.org/obo/UBERON_8410034 UBERON:8410035 biolink:AnatomicalEntity medullary arteriole of lymph node An arteriole that arises from the hilar artery of a lymph node and radiates centrifugally, branching in the medulla. go-plus.json arteriole of medulla of lymph node http://purl.obolibrary.org/obo/UBERON_8410035 UBERON:8410036 biolink:AnatomicalEntity medullary venule of lymph node Medullary venules are a continuation of high endothelial venules which condense repeatedly in the interfollicular cortex and peripheral deep cortical unit and then transition to medullary venules at the corticomedullary junction. The medullary venules condense and return centripetally to the hilar vein. go-plus.json venule of medulla of lymph node http://purl.obolibrary.org/obo/UBERON_8410036 GO:0002845 biolink:BiologicalProcess positive regulation of tolerance induction to tumor cell Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell. go-plus.json up regulation of tolerance induction to tumor cell|activation of tolerance induction to tumor cell|stimulation of tolerance induction to tumor cell|positive regulation of tolerance induction to tumour cell|up-regulation of tolerance induction to tumor cell|upregulation of tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002845 GO:0002846 biolink:BiologicalProcess regulation of T cell tolerance induction to tumor cell Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002846 GO:0002847 biolink:BiologicalProcess negative regulation of T cell tolerance induction to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell. go-plus.json down-regulation of T cell tolerance induction to tumor cell|downregulation of T cell tolerance induction to tumor cell|down regulation of T cell tolerance induction to tumor cell|inhibition of T cell tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002847 GO:0002848 biolink:BiologicalProcess positive regulation of T cell tolerance induction to tumor cell Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell. go-plus.json up regulation of T cell tolerance induction to tumor cell|upregulation of T cell tolerance induction to tumor cell|stimulation of T cell tolerance induction to tumor cell|up-regulation of T cell tolerance induction to tumor cell|activation of T cell tolerance induction to tumor cell http://purl.obolibrary.org/obo/GO_0002848 GO:0002852 biolink:BiologicalProcess regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. go-plus.json http://purl.obolibrary.org/obo/GO_0002852 CHEBI:51316 biolink:ChemicalSubstance haloethene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51316 GO:0002853 biolink:BiologicalProcess negative regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. go-plus.json inhibition of T cell mediated cytotoxicity directed against tumor cell target|down regulation of T cell mediated cytotoxicity directed against tumor cell target|downregulation of T cell mediated cytotoxicity directed against tumor cell target|down-regulation of T cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002853 GO:0002854 biolink:BiologicalProcess positive regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. go-plus.json up-regulation of T cell mediated cytotoxicity directed against tumor cell target|upregulation of T cell mediated cytotoxicity directed against tumor cell target|up regulation of T cell mediated cytotoxicity directed against tumor cell target|activation of T cell mediated cytotoxicity directed against tumor cell target|stimulation of T cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002854 GO:0002855 biolink:BiologicalProcess regulation of natural killer cell mediated immune response to tumor cell Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002855 CHEBI:51312 biolink:ChemicalSubstance dehypoxanthine futalosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_51312 GO:0002850 biolink:BiologicalProcess negative regulation of peripheral T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction. go-plus.json inhibition of peripheral T cell tolerance induction|down regulation of peripheral T cell tolerance induction|downregulation of peripheral T cell tolerance induction|down-regulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002850 UBERON:8410032 biolink:AnatomicalEntity trabecular sinus of lymph node The trabecular sinus is the lymph-filled space outside the trabeculae between lobules of the lymph node. This is a continuation of the subcapsular sinus which receives the afferent vessels and is present beneath the capsule. This space is traversed by both reticular fibers and cells in the lymph. go-plus.json lymph node trabecular sinus http://purl.obolibrary.org/obo/UBERON_8410032 UBERON:8410033 biolink:AnatomicalEntity lymph node vein A vein where lymph node venules condense and which exits at the lymph node hilum. It is also called hilar vein. go-plus.json hilar vein of lymph node|vein of lymph node http://purl.obolibrary.org/obo/UBERON_8410033 GO:0002851 biolink:BiologicalProcess positive regulation of peripheral T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction. go-plus.json up-regulation of peripheral T cell tolerance induction|upregulation of peripheral T cell tolerance induction|up regulation of peripheral T cell tolerance induction|activation of peripheral T cell tolerance induction|stimulation of peripheral T cell tolerance induction http://purl.obolibrary.org/obo/GO_0002851 GO:0061170 biolink:BiologicalProcess negative regulation of hair follicle placode formation Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go-plus.json http://purl.obolibrary.org/obo/GO_0061170 CHEBI:26374 biolink:ChemicalSubstance pterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26374 GO:0061171 biolink:BiologicalProcess establishment of bipolar cell polarity The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane. go-plus.json http://purl.obolibrary.org/obo/GO_0061171 CHEBI:26375 biolink:ChemicalSubstance pterins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26375 GO:0061172 biolink:BiologicalProcess regulation of establishment of bipolar cell polarity Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane. go-plus.json http://purl.obolibrary.org/obo/GO_0061172 CHEBI:26377 biolink:ChemicalSubstance pterocarpans go-plus.json http://purl.obolibrary.org/obo/CHEBI_26377 chebi_ph7_3 GO:0061173 biolink:BiologicalProcess positive regulation of establishment of bipolar cell polarity Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0061173 GO:0061174 biolink:CellularComponent type I terminal bouton Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. go-plus.json type I terminal button http://purl.obolibrary.org/obo/GO_0061174 GO:0061175 biolink:CellularComponent type II terminal bouton Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. go-plus.json type II terminal button http://purl.obolibrary.org/obo/GO_0061175 GO:0061176 biolink:CellularComponent type Ib terminal bouton Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons. go-plus.json type Ib terminal button http://purl.obolibrary.org/obo/GO_0061176 GO:0061177 biolink:CellularComponent type Is terminal bouton Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons. go-plus.json type Is terminal button http://purl.obolibrary.org/obo/GO_0061177 CHEBI:26373 biolink:ChemicalSubstance pteridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26373 GO:0061178 biolink:BiologicalProcess regulation of insulin secretion involved in cellular response to glucose stimulus Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. go-plus.json regulation of insulin secretion in response to glucose http://purl.obolibrary.org/obo/GO_0061178 CHEBI:9519 biolink:ChemicalSubstance thebaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9519 GO:0061179 biolink:BiologicalProcess negative regulation of insulin secretion involved in cellular response to glucose stimulus Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. go-plus.json negative regulation of insulin secretion involved in cellular response to glucose|negative regulation of insulin secretion in response to glucose http://purl.obolibrary.org/obo/GO_0061179 CHEBI:9516 biolink:ChemicalSubstance thapsigargin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9516 chebi_ph7_3 UBERON:8410024 biolink:AnatomicalEntity intestinal junction An anatomical junction between two parts of the intestine. go-plus.json junction of intestine http://purl.obolibrary.org/obo/UBERON_8410024 CHEBI:51310 biolink:ChemicalSubstance futalosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_51310 GO:0002856 biolink:BiologicalProcess negative regulation of natural killer cell mediated immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. go-plus.json downregulation of natural killer cell mediated immune response to tumor cell|down regulation of natural killer cell mediated immune response to tumor cell|inhibition of natural killer cell mediated immune response to tumor cell|down-regulation of natural killer cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002856 GO:0002857 biolink:BiologicalProcess positive regulation of natural killer cell mediated immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. go-plus.json up regulation of natural killer cell mediated immune response to tumor cell|upregulation of natural killer cell mediated immune response to tumor cell|stimulation of natural killer cell mediated immune response to tumor cell|activation of natural killer cell mediated immune response to tumor cell|up-regulation of natural killer cell mediated immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002857 GO:0002858 biolink:BiologicalProcess regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. go-plus.json http://purl.obolibrary.org/obo/GO_0002858 GO:0002859 biolink:BiologicalProcess negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. go-plus.json downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target|down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002859 CHEBI:26349 biolink:ChemicalSubstance proteochondroitin sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26349 GO:0002820 biolink:BiologicalProcess negative regulation of adaptive immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. go-plus.json down-regulation of adaptive immune response|downregulation of adaptive immune response|down regulation of adaptive immune response|inhibition of adaptive immune response http://purl.obolibrary.org/obo/GO_0002820 GO:0002821 biolink:BiologicalProcess positive regulation of adaptive immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. go-plus.json up regulation of adaptive immune response|upregulation of adaptive immune response|stimulation of adaptive immune response|up-regulation of adaptive immune response|activation of adaptive immune response http://purl.obolibrary.org/obo/GO_0002821 CHEBI:51307 biolink:ChemicalSubstance diester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51307 CHEBI:51308 biolink:ChemicalSubstance dinitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_51308 GO:0002822 biolink:BiologicalProcess regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. go-plus.json http://purl.obolibrary.org/obo/GO_0002822 CHEBI:26345 biolink:ChemicalSubstance prostaglandins I go-plus.json http://purl.obolibrary.org/obo/CHEBI_26345 chebi_ph7_3 CHEBI:26346 biolink:ChemicalSubstance prostaglandins J go-plus.json http://purl.obolibrary.org/obo/CHEBI_26346 chebi_ph7_3 CHEBI:26347 biolink:ChemicalSubstance prostanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26347 CHEBI:26348 biolink:ChemicalSubstance prosthetic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_26348 CHEBI:41983 biolink:ChemicalSubstance 4'-epidoxorubicinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_41983 chebi_ph7_3 CHEBI:26343 biolink:ChemicalSubstance prostaglandins G go-plus.json http://purl.obolibrary.org/obo/CHEBI_26343 chebi_ph7_3 CHEBI:26344 biolink:ChemicalSubstance prostaglandins H go-plus.json http://purl.obolibrary.org/obo/CHEBI_26344 chebi_ph7_3 CHEBI:51309 biolink:ChemicalSubstance N(2)-succinyl-L-citrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_51309 CHEBI:26340 biolink:ChemicalSubstance prostaglandins F go-plus.json http://purl.obolibrary.org/obo/CHEBI_26340 chebi_ph7_3 GO:0120097 biolink:CellularComponent glycosylphosphatidylinositol-mannosyltransferase II complex A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p. go-plus.json GPI-MT-I complex http://purl.obolibrary.org/obo/GO_0120097 GO:0120098 biolink:CellularComponent procentriole A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells. go-plus.json http://purl.obolibrary.org/obo/GO_0120098 GO:0120099 biolink:CellularComponent procentriole replication complex A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0120099 GO:0120093 biolink:BiologicalProcess regulation of peptidyl-lysine crotonylation Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0120093 GO:0002827 biolink:BiologicalProcess positive regulation of T-helper 1 type immune response Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response. go-plus.json upregulation of T-helper 1 type immune response|up regulation of T-helper 1 type immune response|activation of T-helper 1 type immune response|stimulation of T-helper 1 type immune response|up-regulation of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002827 GO:0120094 biolink:BiologicalProcess negative regulation of peptidyl-lysine crotonylation Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0120094 GO:0002828 biolink:BiologicalProcess regulation of type 2 immune response Any process that modulates the frequency, rate, or extent of a type 2 immune response. go-plus.json regulation of T-helper 2 type immune response|regulation of Th2 immune response http://purl.obolibrary.org/obo/GO_0002828 GO:0002829 biolink:BiologicalProcess negative regulation of type 2 immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response. go-plus.json inhibition of type 2 immune response|negative regulation of T-helper 2 type immune response|negative regulation of Th2 immune response|down-regulation of type 2 immune response|downregulation of type 2 immune response|down regulation of type 2 immune response http://purl.obolibrary.org/obo/GO_0002829 GO:0120095 biolink:CellularComponent vacuole-isolation membrane contact site An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome. go-plus.json vacuole-phagophore contact site|vacuole-IM contact site|VICS http://purl.obolibrary.org/obo/GO_0120095 GO:0002823 biolink:BiologicalProcess negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. go-plus.json http://purl.obolibrary.org/obo/GO_0002823 GO:0002824 biolink:BiologicalProcess positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. go-plus.json http://purl.obolibrary.org/obo/GO_0002824 GO:0120091 biolink:MolecularActivity jasmonic acid hydrolase Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid. go-plus.json 2-oxoglutarate dioxygenase http://purl.obolibrary.org/obo/GO_0120091 GO:0002825 biolink:BiologicalProcess regulation of T-helper 1 type immune response Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002825 GO:0120092 biolink:MolecularActivity crotonyl-CoA hydratase activity Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. RHEA:45584 go-plus.json http://purl.obolibrary.org/obo/GO_0120092 GO:0002826 biolink:BiologicalProcess negative regulation of T-helper 1 type immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response. go-plus.json down regulation of T-helper 1 type immune response|downregulation of T-helper 1 type immune response|down-regulation of T-helper 1 type immune response|inhibition of T-helper 1 type immune response http://purl.obolibrary.org/obo/GO_0002826 GO:0002830 biolink:BiologicalProcess positive regulation of type 2 immune response Any process that activates or increases the frequency, rate, or extent of a type 2 immune response. go-plus.json up regulation of type 2 immune response|positive regulation of T-helper 2 type immune response|upregulation of type 2 immune response|positive regulation of Th2 immune response|stimulation of type 2 immune response|up-regulation of type 2 immune response|activation of type 2 immune response http://purl.obolibrary.org/obo/GO_0002830 GO:0002831 biolink:BiologicalProcess regulation of response to biotic stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002831 gocheck_do_not_manually_annotate GO:0002832 biolink:BiologicalProcess negative regulation of response to biotic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. go-plus.json down regulation of response to biotic stimulus|downregulation of response to biotic stimulus|down-regulation of response to biotic stimulus|inhibition of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0002832 gocheck_do_not_manually_annotate GO:0002833 biolink:BiologicalProcess positive regulation of response to biotic stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. go-plus.json upregulation of response to biotic stimulus|up regulation of response to biotic stimulus|activation of response to biotic stimulus|stimulation of response to biotic stimulus|up-regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0002833 gocheck_do_not_manually_annotate GO:0061190 biolink:BiologicalProcess regulation of sclerotome development Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. go-plus.json http://purl.obolibrary.org/obo/GO_0061190 GO:0061191 biolink:BiologicalProcess positive regulation of vacuole fusion, non-autophagic Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0061191 GO:0061192 biolink:BiologicalProcess negative regulation of vacuole fusion, non-autophagic Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0061192 GO:0061193 biolink:BiologicalProcess taste bud development The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0061193 GO:0061194 biolink:BiologicalProcess taste bud morphogenesis The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0061194 CHEBI:26354 biolink:ChemicalSubstance protochlorophyllides go-plus.json http://purl.obolibrary.org/obo/CHEBI_26354 GO:0061195 biolink:BiologicalProcess taste bud formation The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0061195 CHEBI:26355 biolink:ChemicalSubstance heme b go-plus.json http://purl.obolibrary.org/obo/CHEBI_26355 GO:0061196 biolink:BiologicalProcess fungiform papilla development The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue. go-plus.json http://purl.obolibrary.org/obo/GO_0061196 GO:0061197 biolink:BiologicalProcess fungiform papilla morphogenesis The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue. go-plus.json http://purl.obolibrary.org/obo/GO_0061197 GO:0061198 biolink:BiologicalProcess fungiform papilla formation The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. go-plus.json http://purl.obolibrary.org/obo/GO_0061198 GO:0061199 biolink:BiologicalProcess striated muscle contraction involved in embryonic body morphogenesis The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0061199 CHEBI:41977 biolink:ChemicalSubstance daunorubicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_41977 CHEBI:9577 biolink:ChemicalSubstance (-)-alpha-thujone go-plus.json http://purl.obolibrary.org/obo/CHEBI_9577 chebi_ph7_3 GO:0002838 biolink:BiologicalProcess negative regulation of immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell. go-plus.json down regulation of immune response to tumor cell|downregulation of immune response to tumor cell|negative regulation of immune response to tumour cell|down-regulation of immune response to tumor cell|inhibition of immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002838 CHEBI:9578 biolink:ChemicalSubstance (-)-thujopsene go-plus.json http://purl.obolibrary.org/obo/CHEBI_9578 chebi_ph7_3 GO:0002839 biolink:BiologicalProcess positive regulation of immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell. go-plus.json up regulation of immune response to tumor cell|activation of immune response to tumor cell|positive regulation of immune response to tumour cell|stimulation of immune response to tumor cell|up-regulation of immune response to tumor cell|upregulation of immune response to tumor cell http://purl.obolibrary.org/obo/GO_0002839 GO:0002834 biolink:BiologicalProcess regulation of response to tumor cell Any process that modulates the frequency, rate, or extent of a response to tumor cell. go-plus.json regulation of response to tumour cell http://purl.obolibrary.org/obo/GO_0002834 GO:0002835 biolink:BiologicalProcess negative regulation of response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell. go-plus.json negative regulation of response to tumour cell|down-regulation of response to tumor cell|downregulation of response to tumor cell|down regulation of response to tumor cell|inhibition of response to tumor cell http://purl.obolibrary.org/obo/GO_0002835 GO:0002836 biolink:BiologicalProcess positive regulation of response to tumor cell Any process that activates or increases the frequency, rate, or extent of a response to tumor cell. go-plus.json positive regulation of response to tumour cell|stimulation of response to tumor cell|up-regulation of response to tumor cell|activation of response to tumor cell|up regulation of response to tumor cell|upregulation of response to tumor cell http://purl.obolibrary.org/obo/GO_0002836 GO:0002837 biolink:BiologicalProcess regulation of immune response to tumor cell Any process that modulates the frequency, rate, or extent of an immune response to tumor cell. go-plus.json regulation of immune response to tumour cell http://purl.obolibrary.org/obo/GO_0002837 GO:0002800 biolink:BiologicalProcess regulation of antifungal peptide secretion Any process that modulates the frequency, rate, or extent of antifungal peptide secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0002800 GO:0002809 biolink:BiologicalProcess negative regulation of antibacterial peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis. go-plus.json downregulation of antibacterial peptide biosynthetic process|down regulation of antibacterial peptide biosynthetic process|inhibition of antibacterial peptide biosynthetic process|down-regulation of antibacterial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002809 CHEBI:41963 biolink:ChemicalSubstance (-)-taxifolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_41963 chebi_ph7_3 GO:0002805 biolink:BiologicalProcess regulation of antimicrobial peptide biosynthetic process Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0002805 GO:0002806 biolink:BiologicalProcess negative regulation of antimicrobial peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis. go-plus.json downregulation of antimicrobial peptide biosynthetic process|down regulation of antimicrobial peptide biosynthetic process|inhibition of antimicrobial peptide biosynthetic process|down-regulation of antimicrobial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002806 GO:0002807 biolink:BiologicalProcess positive regulation of antimicrobial peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis. go-plus.json upregulation of antimicrobial peptide biosynthetic process|stimulation of antimicrobial peptide biosynthetic process|up-regulation of antimicrobial peptide biosynthetic process|activation of antimicrobial peptide biosynthetic process|up regulation of antimicrobial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002807 GO:0002808 biolink:BiologicalProcess regulation of antibacterial peptide biosynthetic process Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0002808 OBO:go#systematic_synonym biolink:OntologyClass Systematic synonym go-plus.json http://purl.obolibrary.org/obo/go#systematic_synonym GO:0002801 biolink:BiologicalProcess negative regulation of antifungal peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion. go-plus.json downregulation of antifungal peptide secretion|down regulation of antifungal peptide secretion|inhibition of antifungal peptide secretion|down-regulation of antifungal peptide secretion http://purl.obolibrary.org/obo/GO_0002801 GO:0002802 biolink:BiologicalProcess positive regulation of antifungal peptide secretion Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion. go-plus.json up regulation of antifungal peptide secretion|upregulation of antifungal peptide secretion|stimulation of antifungal peptide secretion|activation of antifungal peptide secretion|up-regulation of antifungal peptide secretion http://purl.obolibrary.org/obo/GO_0002802 GO:0002803 biolink:BiologicalProcess positive regulation of antibacterial peptide production Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production. go-plus.json stimulation of antibacterial peptide production|up-regulation of antibacterial peptide production|activation of antibacterial peptide production|up regulation of antibacterial peptide production|upregulation of antibacterial peptide production http://purl.obolibrary.org/obo/GO_0002803 GO:0002804 biolink:BiologicalProcess positive regulation of antifungal peptide production Any process that activates or increases the frequency, rate, or extent of antifungal peptide production. go-plus.json up regulation of antifungal peptide production|activation of antifungal peptide production|stimulation of antifungal peptide production|up-regulation of antifungal peptide production|upregulation of antifungal peptide production http://purl.obolibrary.org/obo/GO_0002804 CHEBI:26338 biolink:ChemicalSubstance prostaglandins E go-plus.json http://purl.obolibrary.org/obo/CHEBI_26338 chebi_ph7_3 GO:0002810 biolink:BiologicalProcess regulation of antifungal peptide biosynthetic process Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0002810 GO:0002811 biolink:BiologicalProcess negative regulation of antifungal peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis. go-plus.json down-regulation of antifungal peptide biosynthetic process|inhibition of antifungal peptide biosynthetic process|down regulation of antifungal peptide biosynthetic process|downregulation of antifungal peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0002811 CHEBI:26334 biolink:ChemicalSubstance prostaglandins A go-plus.json http://purl.obolibrary.org/obo/CHEBI_26334 chebi_ph7_3 CHEBI:26335 biolink:ChemicalSubstance prostaglandins B go-plus.json http://purl.obolibrary.org/obo/CHEBI_26335 chebi_ph7_3 CHEBI:26336 biolink:ChemicalSubstance prostaglandins C go-plus.json http://purl.obolibrary.org/obo/CHEBI_26336 chebi_ph7_3 CHEBI:26337 biolink:ChemicalSubstance prostaglandins D go-plus.json http://purl.obolibrary.org/obo/CHEBI_26337 chebi_ph7_3 CHEBI:26333 biolink:ChemicalSubstance prostaglandin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26333 CHEBI:9555 biolink:ChemicalSubstance tioguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9555 chebi_ph7_3 GO:0002816 biolink:BiologicalProcess regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0002816 GO:0002817 biolink:BiologicalProcess negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. go-plus.json down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria http://purl.obolibrary.org/obo/GO_0002817 GO:0002818 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002818 GO:0002819 biolink:BiologicalProcess regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002819 GO:0002812 biolink:BiologicalProcess biosynthetic process of antibacterial peptides active against Gram-negative bacteria The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0002812 GO:0002813 biolink:BiologicalProcess regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0002813 CHEBI:9553 biolink:ChemicalSubstance thioglucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_9553 GO:0002814 biolink:BiologicalProcess negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. go-plus.json down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria http://purl.obolibrary.org/obo/GO_0002814 GO:0002815 biolink:BiologicalProcess biosynthetic process of antibacterial peptides active against Gram-positive bacteria The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0002815 GO:0075720 biolink:BiologicalProcess establishment of episomal latency A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity. go-plus.json establishment of plasmid latency|establishment as a plasmid prophage http://purl.obolibrary.org/obo/GO_0075720 GO:0051753 biolink:MolecularActivity mannan synthase activity Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan. go-plus.json mannan beta-1,4-mannosyltransferase activity|galactomannan beta-1,4-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0051753 GO:0051754 biolink:BiologicalProcess meiotic sister chromatid cohesion, centromeric The cell cycle process in which centromeres of sister chromatids are joined during meiosis. go-plus.json centromeric meiotic sister chromatin cohesion|sister chromatid cohesion at centromere at meiosis I|meiotic sister chromatid cohesion at centromere http://purl.obolibrary.org/obo/GO_0051754 GO:0051751 biolink:MolecularActivity alpha-1,4-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0051751 GO:0051752 biolink:MolecularActivity phosphoglucan, water dikinase activity Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate. MetaCyc:2.7.9.5-RXN|EC:2.7.9.5 go-plus.json ATP:phospho-alpha-glucan, water phosphotransferase activity|PWD|OK1 http://purl.obolibrary.org/obo/GO_0051752 GO:0051757 biolink:BiologicalProcess meiotic sister chromatid separation The process in which sister chromatids are physically detached from each other during meiosis. go-plus.json meiotic sister chromatid resolution http://purl.obolibrary.org/obo/GO_0051757 GO:0051758 biolink:BiologicalProcess homologous chromosome movement towards spindle pole in meiosis I anaphase The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase. go-plus.json meiosis I, homologous chromosome movement towards spindle pole|homologous chromosome movement towards spindle pole during meiosis I http://purl.obolibrary.org/obo/GO_0051758 GO:0051755 biolink:BiologicalProcess meiotic sister chromatid arm separation The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0051755 GO:0051756 biolink:BiologicalProcess meiotic sister chromatid centromere separation The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0051756 GO:0051759 biolink:BiologicalProcess sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II. go-plus.json sister chromosome movement towards spindle pole during meiosis II|meiosis II, sister chromosome movement towards spindle pole http://purl.obolibrary.org/obo/GO_0051759 GO:0036112 biolink:BiologicalProcess medium-chain fatty-acyl-CoA metabolic process The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. go-plus.json medium-chain fatty acyl-CoA metabolism|medium-chain fatty acyl CoA metabolic process http://purl.obolibrary.org/obo/GO_0036112 GO:0036113 biolink:BiologicalProcess very long-chain fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. go-plus.json very long-chain fatty-acyl-CoA catabolism|very long-chain fatty-acyl-CoA degradation|very long-chain fatty-acyl-CoA breakdown http://purl.obolibrary.org/obo/GO_0036113 GO:0036114 biolink:BiologicalProcess medium-chain fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. go-plus.json medium-chain fatty-acyl-CoA breakdown|medium-chain fatty-acyl-CoA catabolism|medium-chain fatty-acyl-CoA degradation http://purl.obolibrary.org/obo/GO_0036114 GO:0036115 biolink:BiologicalProcess fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. go-plus.json fatty-acyl-CoA catabolism|fatty-acyl-CoA degradation|fatty-acyl-CoA breakdown http://purl.obolibrary.org/obo/GO_0036115 GO:0036116 biolink:BiologicalProcess long-chain fatty-acyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json long-chain fatty-acyl-CoA degradation|long-chain fatty-acyl-CoA breakdown|long-chain fatty-acyl-CoA catabolism http://purl.obolibrary.org/obo/GO_0036116 GO:0036117 biolink:CellularComponent hyaluranon cable A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan. go-plus.json HA cable http://purl.obolibrary.org/obo/GO_0036117 GO:0036118 biolink:BiologicalProcess hyaluranon cable assembly A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan. go-plus.json HA cable assembly http://purl.obolibrary.org/obo/GO_0036118 GO:0036119 biolink:BiologicalProcess response to platelet-derived growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. go-plus.json response to PDGF stimulus|response to platelet-derived growth factor stimulus http://purl.obolibrary.org/obo/GO_0036119 CHEBI:75279 biolink:ChemicalSubstance 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75279 chebi_ph7_3 GO:0051750 biolink:MolecularActivity delta3,5-delta2,4-dienoyl-CoA isomerase activity Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA. go-plus.json delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase activity|delta5-delta2,4-dienoyl-CoA isomerase activity http://purl.obolibrary.org/obo/GO_0051750 GO:0036110 biolink:BiologicalProcess cellular response to inositol starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol. go-plus.json http://purl.obolibrary.org/obo/GO_0036110 GO:0036111 biolink:BiologicalProcess very long-chain fatty-acyl-CoA metabolic process The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. go-plus.json very long-chain fatty acyl CoA metabolic process|very long-chain fatty acyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0036111 GO:0051764 biolink:BiologicalProcess actin crosslink formation The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes. go-plus.json formation of actin crosslink|actin crosslinking|actin bundling|bridging actin filaments http://purl.obolibrary.org/obo/GO_0051764 GO:0051765 biolink:MolecularActivity inositol tetrakisphosphate kinase activity Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP. go-plus.json http://purl.obolibrary.org/obo/GO_0051765 GO:0075710 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075710 GO:0051762 biolink:BiologicalProcess sesquiterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. go-plus.json http://purl.obolibrary.org/obo/GO_0051762 GO:0051763 biolink:BiologicalProcess sesquiterpene catabolic process The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. go-plus.json http://purl.obolibrary.org/obo/GO_0051763 CHEBI:145434 biolink:ChemicalSubstance oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_145434 chebi_ph7_3 GO:0075713 biolink:BiologicalProcess establishment of integrated proviral latency A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage. VZ:980 go-plus.json prophage integration|provirus integration http://purl.obolibrary.org/obo/GO_0075713 GO:0051768 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051768 GO:0051769 biolink:BiologicalProcess regulation of nitric-oxide synthase biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme. go-plus.json regulation of nitric-oxide synthase (type 2) biosynthetic process|regulation of nitric-oxide synthase (type 2) biosynthesis|regulation of NOS biosynthetic process|regulation of NOS2 synthase biosynthetic process|regulation of NOS2 synthase biosynthesis|regulation of NOS biosynthesis|regulation of nitric-oxide synthase (type II) biosynthetic process|regulation of nitric-oxide synthase (type II) biosynthesis|regulation of NO synthase biosynthetic process|regulation of NO synthase biosynthesis|regulation of nitric-oxide synthase 2 biosynthetic process http://purl.obolibrary.org/obo/GO_0051769 CHEBI:145437 biolink:ChemicalSubstance uncoupling protein inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_145437 GO:0051766 biolink:MolecularActivity inositol trisphosphate kinase activity Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP. go-plus.json http://purl.obolibrary.org/obo/GO_0051766 GO:0051767 biolink:BiologicalProcess nitric-oxide synthase biosynthetic process The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. go-plus.json NOS2 synthase biosynthesis|NOS2 synthase biosynthetic process|brain nitric-oxide synthase biosynthetic process|NOS biosynthesis|NOS biosynthetic process|NO synthase biosynthesis|NO synthase biosynthetic process|nitric-oxide synthase (type II) biosynthesis|nitric-oxide synthase (type II) biosynthetic process|inducible nitric-oxide synthase biosynthetic process|nitric-oxide synthase 2 biosynthetic process|nitric-oxide synthase (type 2) biosynthetic process|nitric-oxide synthase-1 biosynthetic process|nitric-oxide synthase (type 2) biosynthesis|endothelial nitric-oxide synthase biosynthetic process|nitric-oxide synthase-2 biosynthetic process|nitric-oxide synthase-3 biosynthetic process|NOS1 biosynthesis|NOS2 biosynthesis|NOS3 biosynthesis http://purl.obolibrary.org/obo/GO_0051767 GO:0075716 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075716 GO:0036109 biolink:BiologicalProcess alpha-linolenic acid metabolic process The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. Wikipedia:Linoleic_acid go-plus.json alpha-linolenic acid metabolism|ALA metabolism http://purl.obolibrary.org/obo/GO_0036109 GO:0075717 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075717 GO:0036101 biolink:BiologicalProcess leukotriene B4 catabolic process The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. go-plus.json leukotriene B4 catabolism|leukotriene B4 degradation|LTB4 catabolism|leukotriene B4 breakdown http://purl.obolibrary.org/obo/GO_0036101 GO:0036102 biolink:BiologicalProcess leukotriene B4 metabolic process The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. go-plus.json LTB4 metabolism http://purl.obolibrary.org/obo/GO_0036102 GO:0036103 biolink:BiologicalProcess Kdo2-lipid A metabolic process The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component. go-plus.json Kdo2-lipid A metabolism http://purl.obolibrary.org/obo/GO_0036103 GO:0036104 biolink:BiologicalProcess Kdo2-lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component. go-plus.json Kdo2-lipid A anabolism|Kdo2-lipid A synthesis|Kdo2-lipid A formation|Kdo2-lipid A biosynthesis|di[3-deoxy-D-manno-octulosonyl]-lipid A biosynthesis|KDO(2)-lipid A biosynthesis http://purl.obolibrary.org/obo/GO_0036104 GO:0036105 biolink:MolecularActivity peroxisome membrane class-1 targeting sequence binding Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner. go-plus.json PEX19-dependent mPTS binding|class 1 mPTS binding http://purl.obolibrary.org/obo/GO_0036105 CHEBI:75282 biolink:ChemicalSubstance ergosterol biosynthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75282 GO:0036106 biolink:MolecularActivity peroxisome membrane class-2 targeting sequence binding Binding to a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner. go-plus.json PEX19-independent mPTS binding|class 2 mPTS binding http://purl.obolibrary.org/obo/GO_0036106 CHEBI:75280 biolink:ChemicalSubstance 1-acyl-2-palmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75280 chebi_ph7_3 GO:0036107 biolink:BiologicalProcess 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). go-plus.json 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process|undecaprenyl phosphate alpha-L-Ara4N metabolism http://purl.obolibrary.org/obo/GO_0036107 GO:0036108 biolink:BiologicalProcess 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). go-plus.json undecaprenyl phosphate alpha-L-Ara4N biosynthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0036108 CHEBI:75287 biolink:ChemicalSubstance (S)-dichlorprop(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75287 chebi_ph7_3 CHEBI:75284 biolink:ChemicalSubstance (R)-2-(4-chloro-2-methylphenoxy)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75284 chebi_ph7_3 CHEBI:75285 biolink:ChemicalSubstance (S)-2-(4-chloro-2-methylphenoxy)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75285 chebi_ph7_3 GO:0051760 biolink:BiologicalProcess meiotic sister chromatid cohesion, arms The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis. go-plus.json meiotic sister chromatid cohesion along arms|sister chromatid cohesion along arms at meiosis I http://purl.obolibrary.org/obo/GO_0051760 GO:0099703 biolink:BiologicalProcess induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0099703 goslim_synapse GO:0051761 biolink:BiologicalProcess sesquiterpene metabolic process The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. go-plus.json sesquiterpene metabolism http://purl.obolibrary.org/obo/GO_0051761 CHEBI:75288 biolink:ChemicalSubstance (R)-dichlorprop(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75288 chebi_ph7_3 GO:0036100 biolink:BiologicalProcess leukotriene catabolic process The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. go-plus.json leukotriene breakdown|leukotriene catabolism|leukotriene degradation http://purl.obolibrary.org/obo/GO_0036100 CHEBI:75289 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75289 chebi_ph7_3 GO:0051775 biolink:BiologicalProcess response to redox state Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. go-plus.json redox signal response http://purl.obolibrary.org/obo/GO_0051775 GO:0051776 biolink:BiologicalProcess detection of redox state The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. go-plus.json redox sensing http://purl.obolibrary.org/obo/GO_0051776 CHEBI:9592 biolink:ChemicalSubstance tiglic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9592 GO:0051773 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051773 GO:0051774 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051774 GO:0051779 biolink:MolecularActivity gibberellin 12-aldehyde oxidase activity Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). RHEA:22700|MetaCyc:RXN1F-161 go-plus.json GA12-aldehyde oxidase activity http://purl.obolibrary.org/obo/GO_0051779 GO:0051777 biolink:MolecularActivity ent-kaurenoate oxidase activity Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). RHEA:19241|MetaCyc:1.14.13.79-RXN go-plus.json ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity|ent-kaurenoic acid oxidase activity http://purl.obolibrary.org/obo/GO_0051777 GO:0051778 biolink:MolecularActivity ent-7-alpha-hydroxykaurenoate oxidase activity Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). MetaCyc:RXN1F-160|RHEA:22904 go-plus.json http://purl.obolibrary.org/obo/GO_0051778 GO:0061100 biolink:BiologicalProcess lung neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0061100 GO:0061101 biolink:BiologicalProcess neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. go-plus.json http://purl.obolibrary.org/obo/GO_0061101 GO:0061102 biolink:BiologicalProcess stomach neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. go-plus.json gastric neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061102 CHEBI:75290 biolink:ChemicalSubstance 1-O-octadecyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75290 chebi_ph7_3 GO:0061103 biolink:BiologicalProcess carotid body glomus cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia. go-plus.json http://purl.obolibrary.org/obo/GO_0061103 GO:0061104 biolink:BiologicalProcess adrenal chromaffin cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0061104 GO:0061105 biolink:BiologicalProcess regulation of stomach neuroendocrine cell differentiation Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. go-plus.json http://purl.obolibrary.org/obo/GO_0061105 GO:0061106 biolink:BiologicalProcess negative regulation of stomach neuroendocrine cell differentiation Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. go-plus.json http://purl.obolibrary.org/obo/GO_0061106 CHEBI:75294 biolink:ChemicalSubstance 1-icosanoyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75294 chebi_ph7_3 CHEBI:75291 biolink:ChemicalSubstance epsilon-rhodomycinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75291 chebi_ph7_3 GO:0061107 biolink:BiologicalProcess seminal vesicle development The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. go-plus.json http://purl.obolibrary.org/obo/GO_0061107 GO:0061108 biolink:BiologicalProcess seminal vesicle epithelium development The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061108 CHEBI:51286 biolink:ChemicalSubstance tetracenequinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_51286 CHEBI:9588 biolink:ChemicalSubstance ticlopidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9588 GO:0061109 biolink:BiologicalProcess dense core granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. go-plus.json dense core granule organisation http://purl.obolibrary.org/obo/GO_0061109 CHEBI:75297 biolink:ChemicalSubstance 13-deoxydaunorubicin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75297 chebi_ph7_3 CHEBI:75296 biolink:ChemicalSubstance 13-dihydrodaunorubicin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75296 chebi_ph7_3 GO:0051771 biolink:BiologicalProcess negative regulation of nitric-oxide synthase biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme. go-plus.json downregulation of nitric-oxide synthase 2 biosynthetic process|down regulation of nitric-oxide synthase 2 biosynthetic process|inhibition of nitric-oxide synthase 2 biosynthetic process|down-regulation of nitric-oxide synthase biosynthetic process|negative regulation of NOS2 synthase biosynthesis|negative regulation of NOS2 synthase biosynthetic process|negative regulation of NOS biosynthesis|negative regulation of NOS biosynthetic process|negative regulation of nitric-oxide synthase (type II) biosynthesis|negative regulation of nitric-oxide synthase (type II) biosynthetic process|negative regulation of NO synthase biosynthetic process|negative regulation of NO synthase biosynthesis|downregulation of nitric-oxide synthase biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthesis|down-regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase 2 biosynthetic process|down regulation of nitric-oxide synthase biosynthetic process|inhibition of nitric-oxide synthase biosynthetic process http://purl.obolibrary.org/obo/GO_0051771 CHEBI:51282 biolink:ChemicalSubstance 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51282 GO:0051772 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051772 CHEBI:51283 biolink:ChemicalSubstance hydroxypyruvaldehyde phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51283 CHEBI:51284 biolink:ChemicalSubstance 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51284 GO:0051770 biolink:BiologicalProcess positive regulation of nitric-oxide synthase biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme. go-plus.json stimulation of nitric-oxide synthase biosynthetic process|up-regulation of nitric-oxide synthase biosynthetic process|activation of nitric-oxide synthase biosynthetic process|upregulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NOS2 synthase biosynthetic process|positive regulation of NOS biosynthesis|positive regulation of NOS2 synthase biosynthesis|up regulation of nitric-oxide synthase biosynthetic process|positive regulation of NOS biosynthetic process|up-regulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthesis|positive regulation of nitric-oxide synthase (type 2) biosynthetic process|stimulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NO synthase biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthesis|positive regulation of NO synthase biosynthesis|positive regulation of nitric-oxide synthase (type II) biosynthetic process|activation of nitric-oxide synthase 2 biosynthetic process|upregulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase 2 biosynthetic process|up regulation of nitric-oxide synthase 2 biosynthetic process http://purl.obolibrary.org/obo/GO_0051770 CHEBI:51285 biolink:ChemicalSubstance acenoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51285 GO:0051786 biolink:MolecularActivity all-trans-retinol 13,14-reductase activity Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction. KEGG_REACTION:R07163|MetaCyc:1.3.99.23-RXN|Reactome:R-HSA-8956427|EC:1.3.99.23|RHEA:19193 go-plus.json retinol saturase activity|all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity|(13,14)-all-trans-retinol saturase activity|RetSat activity|all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051786 GO:0075732 biolink:BiologicalProcess viral penetration into host nucleus The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid. VZ:989 go-plus.json viral entry into host nucleus|viral import into host nucleus http://purl.obolibrary.org/obo/GO_0075732 GO:0051787 biolink:MolecularActivity misfolded protein binding Binding to a misfolded protein. Reactome:R-HSA-5324632 go-plus.json http://purl.obolibrary.org/obo/GO_0051787 GO:0051784 biolink:BiologicalProcess negative regulation of nuclear division Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. go-plus.json inhibition of nuclear division|down-regulation of nuclear division|downregulation of nuclear division|down regulation of nuclear division http://purl.obolibrary.org/obo/GO_0051784 GO:0075733 biolink:BiologicalProcess intracellular transport of virus The directed movement of a virus, or part of a virus, within the host cell. go-plus.json viral genome transport in host cell|egress of virus within host cell|viral egress|intracellular virion transport|movement of virus within host cell|intracellular transport of viral material http://purl.obolibrary.org/obo/GO_0075733 GO:0051785 biolink:BiologicalProcess positive regulation of nuclear division Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. go-plus.json upregulation of nuclear division|stimulation of nuclear division|up-regulation of nuclear division|activation of nuclear division|up regulation of nuclear division http://purl.obolibrary.org/obo/GO_0051785 GO:0051788 biolink:BiologicalProcess response to misfolded protein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0051788 UBERON:4300230 biolink:AnatomicalEntity forelimb wing bud A wing bud that develops into a wing go-plus.json http://purl.obolibrary.org/obo/UBERON_4300230 GO:0051789 biolink:BiologicalProcess obsolete response to protein OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. go-plus.json response to protein stimulus|response to protein http://purl.obolibrary.org/obo/GO_0051789 UBERON:4300231 biolink:AnatomicalEntity forelimb wing bud mesenchyme Mesenchyme that is part of a forelimb wing bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300231 CHEBI:51270 biolink:ChemicalSubstance tetracenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_51270 UBERON:4300229 biolink:AnatomicalEntity pelvic fin bud mesenchyme Mesechyme that is part of a pelvic fin bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300229 CHEBI:51276 biolink:ChemicalSubstance thioureas go-plus.json http://purl.obolibrary.org/obo/CHEBI_51276 CHEBI:51277 biolink:ChemicalSubstance thioester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51277 chebi_ph7_3 GO:0051782 biolink:BiologicalProcess negative regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. go-plus.json down-regulation of cell division|inhibition of cell division|down regulation of cell division|downregulation of cell division http://purl.obolibrary.org/obo/GO_0051782 GO:0051783 biolink:BiologicalProcess regulation of nuclear division Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. go-plus.json http://purl.obolibrary.org/obo/GO_0051783 UBERON:4300226 biolink:AnatomicalEntity forelimb bud mesenchyme Mesenchyme that is part of a forelimb bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300226 GO:0051780 biolink:BiologicalProcess behavioral response to nutrient Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus. go-plus.json behavioural response to nutrient http://purl.obolibrary.org/obo/GO_0051780 UBERON:4300227 biolink:AnatomicalEntity hindlimb bud mesenchyme Mesenchyme that is part of a hindlimb bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300227 GO:0051781 biolink:BiologicalProcess positive regulation of cell division Any process that activates or increases the frequency, rate or extent of cell division. go-plus.json up regulation of cell division|activation of cell division|stimulation of cell division|up-regulation of cell division|upregulation of cell division http://purl.obolibrary.org/obo/GO_0051781 UBERON:4300228 biolink:AnatomicalEntity pectoral fin bud mesenchyme Mesechyme that is part of a pectoral fin bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_4300228 GO:0051797 biolink:BiologicalProcess regulation of hair follicle development Any process that modulates the frequency, rate or extent of hair follicle development. go-plus.json http://purl.obolibrary.org/obo/GO_0051797 GO:0002786 biolink:BiologicalProcess regulation of antibacterial peptide production Any process that modulates the frequency, rate, or extent of antibacterial peptide production. go-plus.json http://purl.obolibrary.org/obo/GO_0002786 GO:0051798 biolink:BiologicalProcess positive regulation of hair follicle development Any process that activates or increases the frequency, rate or extent of hair follicle development. go-plus.json up regulation of hair follicle development|activation of hair follicle development|stimulation of hair follicle development|up-regulation of hair follicle development|upregulation of hair follicle development http://purl.obolibrary.org/obo/GO_0051798 GO:0002787 biolink:BiologicalProcess negative regulation of antibacterial peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production. go-plus.json down-regulation of antibacterial peptide production|downregulation of antibacterial peptide production|down regulation of antibacterial peptide production|inhibition of antibacterial peptide production http://purl.obolibrary.org/obo/GO_0002787 GO:0051795 biolink:BiologicalProcess positive regulation of timing of catagen Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. go-plus.json up-regulation of catagen|upregulation of catagen|activation of catagen|stimulation of catagen|up regulation of catagen|positive regulation of catagen http://purl.obolibrary.org/obo/GO_0051795 GO:0002788 biolink:BiologicalProcess regulation of antifungal peptide production Any process that modulates the frequency, rate, or extent of antifungal peptide production. go-plus.json http://purl.obolibrary.org/obo/GO_0002788 GO:0051796 biolink:BiologicalProcess negative regulation of timing of catagen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. go-plus.json down-regulation of catagen|negative regulation of catagen|inhibition of catagen|down regulation of catagen|downregulation of catagen http://purl.obolibrary.org/obo/GO_0051796 GO:0002789 biolink:BiologicalProcess negative regulation of antifungal peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production. go-plus.json down-regulation of antifungal peptide production|inhibition of antifungal peptide production|down regulation of antifungal peptide production|downregulation of antifungal peptide production http://purl.obolibrary.org/obo/GO_0002789 GO:0002782 biolink:BiologicalProcess antifungal peptide secretion The regulated release of an antifungal peptide from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0002782 GO:0002783 biolink:BiologicalProcess antifungal peptide biosynthetic process The chemical reactions and pathways resulting in the formation of an antifungal peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0002783 CHEBI:51269 biolink:ChemicalSubstance acenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_51269 GO:0051799 biolink:BiologicalProcess negative regulation of hair follicle development Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development. go-plus.json down regulation of hair follicle development|downregulation of hair follicle development|down-regulation of hair follicle development|inhibition of hair follicle development http://purl.obolibrary.org/obo/GO_0051799 GO:0002784 biolink:BiologicalProcess regulation of antimicrobial peptide production Any process that modulates the frequency, rate, or extent of antimicrobial peptide production. go-plus.json http://purl.obolibrary.org/obo/GO_0002784 GO:0002785 biolink:BiologicalProcess negative regulation of antimicrobial peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production. go-plus.json down-regulation of antimicrobial peptide production|downregulation of antimicrobial peptide production|down regulation of antimicrobial peptide production|inhibition of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002785 GO:0002780 biolink:BiologicalProcess antibacterial peptide biosynthetic process The chemical reactions and pathways resulting in the formation of an antibacterial peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0002780 GO:0002781 biolink:BiologicalProcess antifungal peptide production The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0002781 gocheck_do_not_annotate GO:0061120 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP by DIF-1 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. go-plus.json http://purl.obolibrary.org/obo/GO_0061120 GO:0061121 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP by DIF-2 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. go-plus.json http://purl.obolibrary.org/obo/GO_0061121 GO:0061122 biolink:BiologicalProcess positive regulation of positive chemotaxis to cAMP Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. go-plus.json http://purl.obolibrary.org/obo/GO_0061122 GO:0061123 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. go-plus.json http://purl.obolibrary.org/obo/GO_0061123 GO:0061124 biolink:BiologicalProcess positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. go-plus.json http://purl.obolibrary.org/obo/GO_0061124 GO:0061125 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. go-plus.json http://purl.obolibrary.org/obo/GO_0061125 GO:0061126 biolink:BiologicalProcess positive regulation of positive chemotaxis to cAMP by DIF-1 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. go-plus.json http://purl.obolibrary.org/obo/GO_0061126 GO:0061127 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP by DIF-1 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. go-plus.json http://purl.obolibrary.org/obo/GO_0061127 GO:0061128 biolink:BiologicalProcess positive regulation of chemotaxis to cAMP by DIF-2 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. go-plus.json http://purl.obolibrary.org/obo/GO_0061128 GO:0061129 biolink:BiologicalProcess negative regulation of positive chemotaxis to cAMP by DIF-2 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. go-plus.json http://purl.obolibrary.org/obo/GO_0061129 GO:0051790 biolink:BiologicalProcess short-chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6. go-plus.json short-chain fatty acid synthesis|short-chain fatty acid formation|short-chain fatty acid biosynthesis|short chain fatty acid biosynthesis|short chain fatty acid biosynthetic process|short-chain fatty acid anabolism http://purl.obolibrary.org/obo/GO_0051790 GO:0099738 biolink:CellularComponent cell cortex region The complete extent of cell cortex that underlies some some region of the plasma membrane. go-plus.json perimembrane region http://purl.obolibrary.org/obo/GO_0099738 gocheck_do_not_annotate UBERON:8410015 biolink:AnatomicalEntity arteriole of colon An arteriole located in the colon. go-plus.json http://purl.obolibrary.org/obo/UBERON_8410015 UBERON:8410016 biolink:AnatomicalEntity descending sigmoid junction The anatomical junction between the descending colon and the sigmoid colon. go-plus.json descending-sigmoid colon junction|descending-sigmoid junction|sigmoid junction http://purl.obolibrary.org/obo/UBERON_8410016 GO:0051793 biolink:BiologicalProcess medium-chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12. go-plus.json medium-chain fatty acid degradation|medium-chain fatty acid catabolism|medium-chain fatty acid breakdown|medium chain fatty acid catabolism|medium chain fatty acid catabolic process http://purl.obolibrary.org/obo/GO_0051793 GO:0051794 biolink:BiologicalProcess regulation of timing of catagen Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. go-plus.json regulation of catagen http://purl.obolibrary.org/obo/GO_0051794 UBERON:8410017 biolink:AnatomicalEntity left colic vein A portal vein that drains the descending colon. It is a tributary of the inferior mesenteric vein, and follows the path of its corresponding artery, the left colic artery. go-plus.json http://purl.obolibrary.org/obo/UBERON_8410017 GO:0051791 biolink:BiologicalProcess medium-chain fatty acid metabolic process The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12. go-plus.json medium chain fatty acid metabolism|medium-chain fatty acid metabolism|medium chain fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0051791 UBERON:8410018 biolink:AnatomicalEntity right colic vein A portal vein that drains the ascending colon. It is a tributary of the superior mesenteric vein, and travels with its corresponding artery, the right colic artery. go-plus.json http://purl.obolibrary.org/obo/UBERON_8410018 GO:0051792 biolink:BiologicalProcess medium-chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12. go-plus.json medium chain fatty acid biosynthetic process|medium chain fatty acid biosynthesis|medium-chain fatty acid biosynthesis|medium-chain fatty acid anabolism|medium-chain fatty acid synthesis|medium-chain fatty acid formation http://purl.obolibrary.org/obo/GO_0051792 GO:0002797 biolink:BiologicalProcess regulation of antibacterial peptide secretion Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0002797 GO:0002798 biolink:BiologicalProcess negative regulation of antibacterial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion. go-plus.json down-regulation of antibacterial peptide secretion|inhibition of antibacterial peptide secretion|down regulation of antibacterial peptide secretion|downregulation of antibacterial peptide secretion http://purl.obolibrary.org/obo/GO_0002798 GO:0002799 biolink:BiologicalProcess positive regulation of antibacterial peptide secretion Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion. go-plus.json up regulation of antibacterial peptide secretion|activation of antibacterial peptide secretion|stimulation of antibacterial peptide secretion|up-regulation of antibacterial peptide secretion|upregulation of antibacterial peptide secretion http://purl.obolibrary.org/obo/GO_0002799 GO:0002793 biolink:BiologicalProcess positive regulation of peptide secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. go-plus.json up-regulation of peptide secretion|upregulation of peptide secretion|up regulation of peptide secretion|activation of peptide secretion|stimulation of peptide secretion http://purl.obolibrary.org/obo/GO_0002793 GO:0002794 biolink:BiologicalProcess regulation of antimicrobial peptide secretion Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0002794 GO:0002795 biolink:BiologicalProcess negative regulation of antimicrobial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion. go-plus.json down-regulation of antimicrobial peptide secretion|inhibition of antimicrobial peptide secretion|down regulation of antimicrobial peptide secretion|downregulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002795 GO:0002796 biolink:BiologicalProcess positive regulation of antimicrobial peptide secretion Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion. go-plus.json up regulation of antimicrobial peptide secretion|activation of antimicrobial peptide secretion|stimulation of antimicrobial peptide secretion|up-regulation of antimicrobial peptide secretion|upregulation of antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002796 GO:0002790 biolink:BiologicalProcess peptide secretion The controlled release of a peptide from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0002790 GO:0002791 biolink:BiologicalProcess regulation of peptide secretion Any process that modulates the frequency, rate, or extent of peptide secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0002791 GO:0002792 biolink:BiologicalProcess negative regulation of peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. go-plus.json down regulation of peptide secretion|downregulation of peptide secretion|down-regulation of peptide secretion|inhibition of peptide secretion http://purl.obolibrary.org/obo/GO_0002792 GO:0061110 biolink:BiologicalProcess dense core granule biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule. go-plus.json http://purl.obolibrary.org/obo/GO_0061110 GO:0061111 biolink:BiologicalProcess epithelial-mesenchymal cell signaling involved in lung development Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ. go-plus.json epithelial-mesenchymal cell signalling involved in lung development http://purl.obolibrary.org/obo/GO_0061111 GO:0061112 biolink:BiologicalProcess negative regulation of bud outgrowth involved in lung branching Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching. go-plus.json http://purl.obolibrary.org/obo/GO_0061112 UBERON:8410009 biolink:AnatomicalEntity arteriole of anorectum An arteriole that is located in the anorectum. go-plus.json anorectum arteriole http://purl.obolibrary.org/obo/UBERON_8410009 GO:0061113 biolink:BiologicalProcess pancreas morphogenesis Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061113 GO:0061114 biolink:BiologicalProcess branching involved in pancreas morphogenesis The process in which the branches of the pancreas are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061114 GO:0061115 biolink:BiologicalProcess lung proximal/distal axis specification The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli. go-plus.json http://purl.obolibrary.org/obo/GO_0061115 GO:0061116 biolink:BiologicalProcess ductus venosus closure The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth. go-plus.json http://purl.obolibrary.org/obo/GO_0061116 GO:0061117 biolink:BiologicalProcess negative regulation of heart growth Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061117 GO:0061118 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. go-plus.json http://purl.obolibrary.org/obo/GO_0061118 GO:0061119 biolink:BiologicalProcess regulation of positive chemotaxis to cAMP by chlorinated alkylphenone Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. go-plus.json http://purl.obolibrary.org/obo/GO_0061119 UBERON:8410001 biolink:AnatomicalEntity small intestine venule Venule of villus of small intestine. go-plus.json venule of small intestine http://purl.obolibrary.org/obo/UBERON_8410001 UBERON:8410002 biolink:AnatomicalEntity small intestine lymphatic vessel A lymphatic vessel that supplies the small intestine. go-plus.json lymphatic vessel of small intestine http://purl.obolibrary.org/obo/UBERON_8410002 UBERON:8410004 biolink:AnatomicalEntity small intestine arteriole Arteriole of villus of small intestine. go-plus.json arteriole of small intestine|small intestine villus arteriole|arteriole of villus of small intestine http://purl.obolibrary.org/obo/UBERON_8410004 UBERON:8410008 biolink:AnatomicalEntity venule of anorectum A venule that is located in the anorectum. go-plus.json anorectum venule http://purl.obolibrary.org/obo/UBERON_8410008 GO:0002764 biolink:BiologicalProcess immune response-regulating signaling pathway The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response. go-plus.json immune response-regulating signalling pathway http://purl.obolibrary.org/obo/GO_0002764 GO:0002765 biolink:BiologicalProcess immune response-inhibiting signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002765 GO:0002766 biolink:BiologicalProcess innate immune response-inhibiting signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002766 GO:0002767 biolink:BiologicalProcess immune response-inhibiting cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response. go-plus.json immune response-inhibiting cell surface receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002767 GO:0002760 biolink:BiologicalProcess positive regulation of antimicrobial humoral response Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response. go-plus.json up regulation of antimicrobial humoral response|upregulation of antimicrobial humoral response|stimulation of antimicrobial humoral response|up-regulation of antimicrobial humoral response|activation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0002760 GO:0002761 biolink:BiologicalProcess regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0002761 GO:0002762 biolink:BiologicalProcess negative regulation of myeloid leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. go-plus.json down regulation of myeloid leukocyte differentiation|downregulation of myeloid leukocyte differentiation|down-regulation of myeloid leukocyte differentiation|inhibition of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0002762 GO:0002763 biolink:BiologicalProcess positive regulation of myeloid leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. go-plus.json upregulation of myeloid leukocyte differentiation|up regulation of myeloid leukocyte differentiation|activation of myeloid leukocyte differentiation|stimulation of myeloid leukocyte differentiation|up-regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0002763 CHEBI:26287 biolink:ChemicalSubstance propane-1,3-diols go-plus.json http://purl.obolibrary.org/obo/CHEBI_26287 CHEBI:26288 biolink:ChemicalSubstance propanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26288 GO:0061140 biolink:BiologicalProcess lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. go-plus.json http://purl.obolibrary.org/obo/GO_0061140 CHEBI:26282 biolink:ChemicalSubstance propanals go-plus.json http://purl.obolibrary.org/obo/CHEBI_26282 GO:0061141 biolink:BiologicalProcess lung ciliated cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061141 GO:0061142 biolink:BiologicalProcess mesothelial-mesenchymal cell signaling involved in early lung development Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung. go-plus.json mesothelial-mesenchymal cell signalling involved in early lung development http://purl.obolibrary.org/obo/GO_0061142 GO:0061143 biolink:BiologicalProcess alveolar primary septum development The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms. go-plus.json http://purl.obolibrary.org/obo/GO_0061143 CHEBI:26284 biolink:ChemicalSubstance propane-1,2-diols go-plus.json http://purl.obolibrary.org/obo/CHEBI_26284 GO:0061144 biolink:BiologicalProcess alveolar secondary septum development The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule. go-plus.json http://purl.obolibrary.org/obo/GO_0061144 GO:0061145 biolink:BiologicalProcess lung smooth muscle development The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061145 GO:0061146 biolink:BiologicalProcess Peyer's patch morphogenesis The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0061146 GO:0061147 biolink:BiologicalProcess endocardial endothelium development The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go-plus.json http://purl.obolibrary.org/obo/GO_0061147 GO:0061148 biolink:BiologicalProcess extracellular matrix organization involved in endocardium development A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go-plus.json extracellular matrix organisation involved in endocardium development http://purl.obolibrary.org/obo/GO_0061148 CHEBI:26292 biolink:ChemicalSubstance propanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_26292 GO:0061149 biolink:BiologicalProcess BMP signaling pathway involved in ureter morphogenesis A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder. go-plus.json BMP signalling pathway involved in ureter morphogenesis http://purl.obolibrary.org/obo/GO_0061149 GO:0002768 biolink:BiologicalProcess immune response-regulating cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response. go-plus.json immune response-regulating cell surface receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002768 GO:0002769 biolink:BiologicalProcess natural killer cell inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response. go-plus.json natural killer cell inhibitory signalling pathway|killer cell inhibitory receptor signaling pathway|NK cell inhibitory signaling pathway|inhibitory KIR signaling pathway|Ly49 inhibitory receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002769 GO:0002775 biolink:BiologicalProcess antimicrobial peptide production The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. go-plus.json http://purl.obolibrary.org/obo/GO_0002775 gocheck_do_not_annotate GO:0002776 biolink:BiologicalProcess antimicrobial peptide secretion The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. go-plus.json http://purl.obolibrary.org/obo/GO_0002776 GO:0002777 biolink:BiologicalProcess antimicrobial peptide biosynthetic process The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. go-plus.json http://purl.obolibrary.org/obo/GO_0002777 GO:0002778 biolink:BiologicalProcess antibacterial peptide production The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0002778 gocheck_do_not_annotate GO:0002771 biolink:BiologicalProcess inhibitory killer cell immunoglobulin-like receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response. go-plus.json KIR signaling pathway|inhibitory killer cell immunoglobulin-like receptor signalling pathway|killer cell inhibitory receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002771 GO:0002772 biolink:BiologicalProcess inhibitory C-type lectin receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response. go-plus.json inhibitory C-type lectin receptor signalling pathway|Ly49 inhibitory receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002772 GO:0002773 biolink:BiologicalProcess B cell inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response. go-plus.json B-cell inhibitory signaling pathway|B cell inhibitory signalling pathway|B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway http://purl.obolibrary.org/obo/GO_0002773 GO:0002774 biolink:BiologicalProcess Fc receptor mediated inhibitory signaling pathway A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json Fc receptor mediated inhibitory signalling pathway|Fc-receptor mediated inhibitory signaling pathway http://purl.obolibrary.org/obo/GO_0002774 GO:0002770 biolink:BiologicalProcess T cell inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response. go-plus.json T cell inhibitory signalling pathway|T-lymphocyte inhibitory signaling pathway|T-cell inhibitory signaling pathway|T lymphocyte inhibitory signaling pathway http://purl.obolibrary.org/obo/GO_0002770 GO:0061130 biolink:BiologicalProcess pancreatic bud formation The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. go-plus.json http://purl.obolibrary.org/obo/GO_0061130 GO:0061131 biolink:BiologicalProcess pancreas field specification The process in which a specific region of the gut is delineated into the area in which the pancreas will develop. go-plus.json http://purl.obolibrary.org/obo/GO_0061131 GO:0061132 biolink:BiologicalProcess pancreas induction The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_0061132 GO:0061133 biolink:MolecularActivity endopeptidase activator activity Binds to and increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. go-plus.json http://purl.obolibrary.org/obo/GO_0061133 CHEBI:26296 biolink:ChemicalSubstance propanoyl-CoAs go-plus.json http://purl.obolibrary.org/obo/CHEBI_26296 GO:0061134 biolink:MolecularActivity peptidase regulator activity Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0061134 GO:0061135 biolink:MolecularActivity endopeptidase regulator activity Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. go-plus.json http://purl.obolibrary.org/obo/GO_0061135 GO:0061136 biolink:BiologicalProcess regulation of proteasomal protein catabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. go-plus.json http://purl.obolibrary.org/obo/GO_0061136 GO:0061137 biolink:BiologicalProcess bud dilation The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch. go-plus.json http://purl.obolibrary.org/obo/GO_0061137 GO:0061138 biolink:BiologicalProcess morphogenesis of a branching epithelium The process in which the anatomical structures of a branched epithelium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061138 GO:0061139 biolink:BiologicalProcess bud field specification The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0061139 GO:0002779 biolink:BiologicalProcess antibacterial peptide secretion The regulated release of an antibacterial peptide from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0002779 CHEBI:90837 biolink:ChemicalSubstance 3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_90837 CHEBI:90838 biolink:ChemicalSubstance O-(N-acetyl-beta-D-glucosaminyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90838 chebi_ph7_3 CHEBI:90839 biolink:ChemicalSubstance 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_90839 CHEBI:90832 biolink:ChemicalSubstance NMNH(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90832 chebi_ph7_3 CHEBI:90833 biolink:ChemicalSubstance 5-hydroperoxy-15-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_90833 GO:0036192 biolink:MolecularActivity 3-hydroxyindolin-2-one monooxygenase activity Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O. EC:1.14.14.109|RHEA:31927|KEGG_REACTION:R07422 go-plus.json 3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming) http://purl.obolibrary.org/obo/GO_0036192 GO:0036193 biolink:MolecularActivity 2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O. RHEA:31939|EC:1.14.14.110|KEGG_REACTION:R07423 go-plus.json http://purl.obolibrary.org/obo/GO_0036193 GO:0036194 biolink:CellularComponent muscle cell projection A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. go-plus.json myopodia|myocyte projection|muscle arm http://purl.obolibrary.org/obo/GO_0036194 GO:0036195 biolink:CellularComponent muscle cell projection membrane The portion of the plasma membrane surrounding a muscle cell projection. go-plus.json http://purl.obolibrary.org/obo/GO_0036195 GO:0036196 biolink:BiologicalProcess zymosterol metabolic process The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol). go-plus.json http://purl.obolibrary.org/obo/GO_0036196 GO:0036197 biolink:BiologicalProcess zymosterol biosynthetic process The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol). MetaCyc:PWY-6074|UniPathway:UPA00770 go-plus.json zymosterol anabolism|zymosterol synthesis|zymosterol biosynthesis|zymosterol formation http://purl.obolibrary.org/obo/GO_0036197 GO:0036198 biolink:BiologicalProcess dTMP salvage Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis. UniPathway:UPA00578 go-plus.json deoxythymidine monophosphate biosynthesis via salvage pathway|dTMP biosynthesis via salvage pathway http://purl.obolibrary.org/obo/GO_0036198 GO:0036199 biolink:MolecularActivity cholest-4-en-3-one 26-monooxygenase activity Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate. EC:1.14.15.29|RHEA:51564|KEGG_REACTION:R09859 go-plus.json http://purl.obolibrary.org/obo/GO_0036199 CHEBI:75207 biolink:ChemicalSubstance 2-palmitoyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75207 chebi_ph7_3 CHEBI:75204 biolink:ChemicalSubstance (S)-3,5-dihydroxyphenylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75204 chebi_ph7_3 CHEBI:75205 biolink:ChemicalSubstance 2'-linoleoylcardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75205 chebi_ph7_3 CHEBI:75208 biolink:ChemicalSubstance 2-stearoyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75208 chebi_ph7_3 GO:0036190 biolink:MolecularActivity indole-2-monooxygenase activity Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O. EC:1.14.14.153|RHEA:31899|KEGG_REACTION:R07403 go-plus.json http://purl.obolibrary.org/obo/GO_0036190 GO:0036191 biolink:MolecularActivity indolin-2-one monooxygenase activity Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O. RHEA:31919|EC:1.14.14.157|KEGG_REACTION:R07421 go-plus.json indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating) http://purl.obolibrary.org/obo/GO_0036191 CHEBI:75209 biolink:ChemicalSubstance 2-linoleoyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75209 chebi_ph7_3 GO:0120109 biolink:BiologicalProcess mitotic telomere clustering and tethering at nuclear periphery The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0120109 GO:0120105 biolink:CellularComponent mitotic actomyosin contractile ring, intermediate layer The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer. go-plus.json actomyosin contractile ring, intermediate layer http://purl.obolibrary.org/obo/GO_0120105 CHEBI:90818 biolink:ChemicalSubstance 18(R)-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90818 chebi_ph7_3 GO:0120106 biolink:CellularComponent mitotic actomyosin contractile ring, distal actin filament layer The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to. go-plus.json actomyosin contractile ring, distal actin filament layer http://purl.obolibrary.org/obo/GO_0120106 CHEBI:90819 biolink:ChemicalSubstance 15(R)-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90819 chebi_ph7_3 GO:0120107 biolink:CellularComponent bacterial-type flagellum rotor complex The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation. go-plus.json http://purl.obolibrary.org/obo/GO_0120107 GO:0120108 biolink:MolecularActivity DNA-3'-diphospho-5'-guanosine diphosphatase Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H(2)O <=> (DNA)-3'-phosphate + GMP. RHEA:52140|EC:3.6.1.72 go-plus.json DNA-3'pp5'G guanylate hydrolase http://purl.obolibrary.org/obo/GO_0120108 GO:0036189 biolink:MolecularActivity abieta-7,13-diene hydroxylase activity Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O. RHEA:26217|KEGG_REACTION:R06351|MetaCyc:RXN-8507|EC:1.14.14.144 go-plus.json abietadiene hydroxylase http://purl.obolibrary.org/obo/GO_0036189 GO:0120101 biolink:CellularComponent bacterial-type flagellum stator complex A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. go-plus.json bacterial-type flagellum torque generator complex|bacterial-type flagellum motor force generator complex http://purl.obolibrary.org/obo/GO_0120101 CHEBI:90825 biolink:ChemicalSubstance 18-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90825 chebi_ph7_3 GO:0120102 biolink:CellularComponent bacterial-type flagellum secretion apparatus A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament. go-plus.json bacterial-type flagellum export apparatus http://purl.obolibrary.org/obo/GO_0120102 CHEBI:90826 biolink:ChemicalSubstance (5S)-hydroperoxy-18-hydroxy-EPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90826 chebi_ph7_3 GO:0120103 biolink:CellularComponent centriolar subdistal appendage A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68. go-plus.json subdistal appendage of mother centriole|subdistal appendage of centriole|subdistal appendage of basal body http://purl.obolibrary.org/obo/GO_0120103 GO:0120104 biolink:CellularComponent mitotic actomyosin contractile ring, proximal layer The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located. go-plus.json actomyosin contractile ring, proximal layer http://purl.obolibrary.org/obo/GO_0120104 CHEBI:90821 biolink:ChemicalSubstance 15-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90821 chebi_ph7_3 CHEBI:90822 biolink:ChemicalSubstance 5-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90822 chebi_ph7_3 CHEBI:90823 biolink:ChemicalSubstance 13-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90823 chebi_ph7_3 GO:0120100 biolink:CellularComponent bacterial-type flagellum motor A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation. go-plus.json http://purl.obolibrary.org/obo/GO_0120100 CHEBI:90824 biolink:ChemicalSubstance (7Z,10Z,13R,14E,16Z,19Z)-13-hydroxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90824 chebi_ph7_3 GO:0036181 biolink:BiologicalProcess protein localization to linear element A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase. go-plus.json protein localisation to linear element http://purl.obolibrary.org/obo/GO_0036181 GO:0036182 biolink:BiologicalProcess asperthecin metabolic process The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. go-plus.json asperthecin metabolism http://purl.obolibrary.org/obo/GO_0036182 GO:0036183 biolink:BiologicalProcess asperthecin catabolic process The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. go-plus.json asperthecin breakdown|asperthecin catabolism|asperthecin degradation http://purl.obolibrary.org/obo/GO_0036183 GO:0036184 biolink:BiologicalProcess asperthecin biosynthetic process The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. go-plus.json asperthecin synthesis|asperthecin formation|asperthecin biosynthesis http://purl.obolibrary.org/obo/GO_0036184 CHEBI:90820 biolink:ChemicalSubstance 11(R)-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90820 chebi_ph7_3 GO:0036185 biolink:MolecularActivity 13-lipoxin reductase activity Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+. Reactome:R-HSA-2161844 go-plus.json http://purl.obolibrary.org/obo/GO_0036185 GO:0036186 biolink:CellularComponent early phagosome membrane The lipid bilayer surrounding an early phagosome. go-plus.json early phagocytic vesicle membrane http://purl.obolibrary.org/obo/GO_0036186 CHEBI:75203 biolink:ChemicalSubstance 2'-lauroylcardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75203 chebi_ph7_3 GO:0036187 biolink:BiologicalProcess cell growth mode switching, budding to filamentous The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans. go-plus.json yeast to hyphal transition http://purl.obolibrary.org/obo/GO_0036187 CHEBI:75200 biolink:ChemicalSubstance phosphatidylglycerol 36:2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75200 chebi_ph7_3 GO:0036188 biolink:MolecularActivity abieta-7,13-dien-18-al dehydrogenase activity Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+. EC:1.2.1.74|KEGG_REACTION:R06357|RHEA:26225|MetaCyc:1.2.1.74-RXN go-plus.json abietadienal dehydrogenase http://purl.obolibrary.org/obo/GO_0036188 CHEBI:75201 biolink:ChemicalSubstance 2-dodecanoyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75201 chebi_ph7_3 CHEBI:75216 biolink:ChemicalSubstance 1-O-octadecyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75216 chebi_ph7_3 CHEBI:75219 biolink:ChemicalSubstance 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75219 chebi_ph7_3 GO:0036180 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to biotic stimulus The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036180 CHEBI:16919 biolink:ChemicalSubstance creatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16919 GO:0120116 biolink:BiologicalProcess glucagon processing The formation of mature glucagon by proteolysis of the precursor proglucagon. go-plus.json http://purl.obolibrary.org/obo/GO_0120116 GO:0120117 biolink:BiologicalProcess T cell meandering migration The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs). go-plus.json lymph node surveillance|T cell meandering search http://purl.obolibrary.org/obo/GO_0120117 CHEBI:16918 biolink:ChemicalSubstance gallate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16918 chebi_ph7_3 GO:0120118 biolink:CellularComponent flagella connector A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum. go-plus.json http://purl.obolibrary.org/obo/GO_0120118 GO:0120119 biolink:CellularComponent flagellum attachment zone A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species. go-plus.json FAZ http://purl.obolibrary.org/obo/GO_0120119 CHEBI:16916 biolink:ChemicalSubstance oligosaccharide phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16916 GO:0120112 biolink:BiologicalProcess UDP-glucose transmembrane transport into endoplasmic reticulum The directed movement of UDP-glucose from cytosol to endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0120112 GO:0036178 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to neutral pH The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036178 CHEBI:16913 biolink:ChemicalSubstance N-methylphenylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16913 CHEBI:90858 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1<->1')-N-acylsphingosine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90858 chebi_ph7_3 GO:0120113 biolink:BiologicalProcess cytoplasm to vacuole transport by the NVT pathway A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe. go-plus.json protein localization by the Nbr1-mediated vacuolar targeting pathway|protein localization by the NVT pathway|cytoplasm to vacuole targeting|cytoplasm-to-vacuole targeting http://purl.obolibrary.org/obo/GO_0120113 GO:0036179 biolink:BiologicalProcess osteoclast maturation A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes. go-plus.json chondroclast maturation http://purl.obolibrary.org/obo/GO_0036179 CHEBI:90859 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90859 chebi_ph7_3 CHEBI:16914 biolink:ChemicalSubstance salicylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16914 GO:0120114 biolink:CellularComponent Sm-like protein family complex A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles. go-plus.json http://purl.obolibrary.org/obo/GO_0120114 GO:0120115 biolink:CellularComponent Lsm2-8 complex A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0120115 CHEBI:16912 biolink:ChemicalSubstance trans-1,2-dithiane-4,5-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16912 CHEBI:16910 biolink:ChemicalSubstance mandelonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_16910 chebi_ph7_3 GO:0120110 biolink:BiologicalProcess interphase mitotic telomere clustering The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope. go-plus.json mitotic telomere clustering during interphase http://purl.obolibrary.org/obo/GO_0120110 CHEBI:90856 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNac-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90856 chebi_ph7_3 GO:0120111 biolink:CellularComponent neuron projection cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. go-plus.json http://purl.obolibrary.org/obo/GO_0120111 CHEBI:90857 biolink:ChemicalSubstance bacteriochlorophyllide g(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90857 chebi_ph7_3 GO:0036170 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to starvation The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment. go-plus.json http://purl.obolibrary.org/obo/GO_0036170 CHEBI:90850 biolink:ChemicalSubstance 13(S)-HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90850 chebi_ph7_3 CHEBI:75210 biolink:ChemicalSubstance 3,5-dihydroxyphenylglyoxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75210 chebi_ph7_3 GO:0036171 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to chemical stimulus The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036171 GO:0036172 biolink:BiologicalProcess thiamine salvage A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis. MetaCyc:PWY-6898|MetaCyc:PWY-6897|MetaCyc:PWY-6896 go-plus.json http://purl.obolibrary.org/obo/GO_0036172 GO:0036173 biolink:MolecularActivity thiosulfate binding Binding to a thiosulfate, a sulfur oxide that has formula O3S2. go-plus.json http://purl.obolibrary.org/obo/GO_0036173 GO:0036174 biolink:MolecularActivity butane monooxygenase activity Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O. go-plus.json sBMO|soluble butane monooxygenase http://purl.obolibrary.org/obo/GO_0036174 GO:0036175 biolink:MolecularActivity ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin. Reactome:R-HSA-111742|Reactome:R-HSA-8866405 go-plus.json http://purl.obolibrary.org/obo/GO_0036175 GO:0036176 biolink:BiologicalProcess response to neutral pH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json http://purl.obolibrary.org/obo/GO_0036176 GO:0036177 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to pH The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json http://purl.obolibrary.org/obo/GO_0036177 CHEBI:145497 biolink:ChemicalSubstance N-acylethanolamine phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145497 chebi_ph7_3 GO:0051702 biolink:BiologicalProcess biological process involved in interaction with symbiont An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. go-plus.json interaction with symbiont http://purl.obolibrary.org/obo/GO_0051702 GO:0051703 biolink:BiologicalProcess biological process involved in intraspecies interaction between organisms Any process in which an organism has an effect on an organism of the same species. go-plus.json intraspecies interaction between organisms|intraspecies interaction with other organisms http://purl.obolibrary.org/obo/GO_0051703 gocheck_do_not_annotate|goslim_pir GO:0051700 biolink:MolecularActivity fructosyl-amino acid oxidase activity Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2. go-plus.json FAOD activity http://purl.obolibrary.org/obo/GO_0051700 GO:0051701 biolink:BiologicalProcess biological process involved in interaction with host An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. go-plus.json growth of symbiont in host|interaction with host|growth of symbiont in host organelle|growth of symbiont in host cell|growth of symbiont in host vacuole http://purl.obolibrary.org/obo/GO_0051701 GO:0051706 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051706 GO:0051707 biolink:BiologicalProcess response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. go-plus.json http://purl.obolibrary.org/obo/GO_0051707 GO:0051704 biolink:BiologicalProcess multi-organism process A biological process which involves another organism of the same or different species. go-plus.json physiological interaction with other organism|interaction between organisms|physiological interaction between organisms http://purl.obolibrary.org/obo/GO_0051704 gocheck_do_not_annotate|goslim_pir CHEBI:16908 biolink:ChemicalSubstance NADH go-plus.json http://purl.obolibrary.org/obo/CHEBI_16908 GO:0051705 biolink:BiologicalProcess obsolete multi-organism behavior OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species. go-plus.json behavioural interaction between organisms|behavioral signalling|behavioral signaling|behavioral interaction between organisms|behavioural interaction with other organism|behavioral interaction with other organism http://purl.obolibrary.org/obo/GO_0051705 goslim_pir GO:0120127 biolink:BiologicalProcess response to zinc ion starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion. go-plus.json http://purl.obolibrary.org/obo/GO_0120127 CHEBI:16907 biolink:ChemicalSubstance 4-nitroquinoline N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16907 chebi_ph7_3 GO:0051708 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051708 CHEBI:16904 biolink:ChemicalSubstance fluoren-9-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16904 chebi_ph7_3 CHEBI:16905 biolink:ChemicalSubstance keto-D-fructose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16905 GO:0051709 biolink:BiologicalProcess regulation of killing of cells of other organism Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism. go-plus.json regulation of killing of cells of another organism|modulation by organism of apoptotic process in other organism involved in symbiotic interaction|modulation of programmed cell death in other organism|modulation of programmed cell death in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051709 GO:0120123 biolink:CellularComponent ubiquitin activating enzyme complex A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. go-plus.json E1 complex|E1 ubiquitin-activating enzyme http://purl.obolibrary.org/obo/GO_0120123 GO:0036167 biolink:BiologicalProcess phenotypic switching in response to host A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. go-plus.json http://purl.obolibrary.org/obo/GO_0036167 GO:0036168 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms in response to heat The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature. go-plus.json http://purl.obolibrary.org/obo/GO_0036168 CHEBI:16903 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-O-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16903 chebi_ph7_3 GO:0120124 biolink:CellularComponent membrane fusion priming complex A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes. go-plus.json GATE-16 complex|LMA1 complex http://purl.obolibrary.org/obo/GO_0120124 GO:0120125 biolink:CellularComponent PNGase complex A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. go-plus.json http://purl.obolibrary.org/obo/GO_0120125 GO:0036169 biolink:MolecularActivity 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2. Reactome:R-HSA-2162195 go-plus.json http://purl.obolibrary.org/obo/GO_0036169 CHEBI:90849 biolink:ChemicalSubstance geranylgeranyl bacteriochlorophyllide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90849 chebi_ph7_3 CHEBI:16900 biolink:ChemicalSubstance chlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_16900 GO:0120126 biolink:BiologicalProcess response to copper ion starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion. go-plus.json http://purl.obolibrary.org/obo/GO_0120126 CHEBI:16901 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_16901 chebi_ph7_3 GO:0120120 biolink:CellularComponent bilobe structure A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone). go-plus.json kinetoplastid flagellar hook complex http://purl.obolibrary.org/obo/GO_0120120 GO:0120121 biolink:CellularComponent tripartite attachment complex A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body. go-plus.json TAC http://purl.obolibrary.org/obo/GO_0120121 GO:0120122 biolink:BiologicalProcess prolactin metabolic process The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals. go-plus.json prolactin metabolism http://purl.obolibrary.org/obo/GO_0120122 CHEBI:75220 biolink:ChemicalSubstance 1-stearoyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75220 chebi_ph7_3 GO:0036160 biolink:BiologicalProcess melanocyte-stimulating hormone secretion The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation. go-plus.json MSH secretion http://purl.obolibrary.org/obo/GO_0036160 CHEBI:90840 biolink:ChemicalSubstance O-(N-acetyl-beta-D-glucosaminyl)-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90840 chebi_ph7_3 GO:0036161 biolink:BiologicalProcess calcitonin secretion The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0036161 GO:0036162 biolink:BiologicalProcess oxytocin production The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain. go-plus.json oxytocin biosynthesis|oxytocin secretion http://purl.obolibrary.org/obo/GO_0036162 GO:0036163 biolink:MolecularActivity 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2. RHEA:44768|KEGG_REACTION:R06866 go-plus.json http://purl.obolibrary.org/obo/GO_0036163 GO:0036164 biolink:BiologicalProcess cell-abiotic substrate adhesion The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules. go-plus.json cell-abiotic surface adhesion http://purl.obolibrary.org/obo/GO_0036164 GO:0036165 biolink:BiologicalProcess invasive growth in response to heat The growth of colonies in filamentous chains of cells as a result of an increase in temperature. go-plus.json invasive growth in response to high temperature|invasive growth in response to elevated temperature|invasive growth in response to temperature stimulus http://purl.obolibrary.org/obo/GO_0036165 GO:0036166 biolink:BiologicalProcess phenotypic switching A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues. go-plus.json phenotypic dimorphism http://purl.obolibrary.org/obo/GO_0036166 CHEBI:75239 biolink:ChemicalSubstance 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75239 chebi_ph7_3 GO:0051710 biolink:BiologicalProcess regulation of cytolysis in other organism Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism. go-plus.json regulation of cytolysis of cells of another, non-host, organism|regulation of cytolysis of cells of another organism http://purl.obolibrary.org/obo/GO_0051710 CHEBI:75238 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75238 chebi_ph7_3 GO:0051713 biolink:BiologicalProcess negative regulation of cytolysis in other organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism. go-plus.json down regulation of cytolysis of cells of another organism|inhibition of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another organism|down-regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another, non-host, organism|downregulation of cytolysis of cells of another organism http://purl.obolibrary.org/obo/GO_0051713 GO:0051714 biolink:BiologicalProcess positive regulation of cytolysis in other organism Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism. go-plus.json upregulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another organism|stimulation of cytolysis of cells of another organism|activation of cytolysis of cells of another organism|up-regulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another, non-host, organism|up regulation of cytolysis of cells of another organism http://purl.obolibrary.org/obo/GO_0051714 GO:0051711 biolink:BiologicalProcess negative regulation of killing of cells of other organism Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism. go-plus.json downregulation of killing of cells of another organism|down regulation of killing of cells of another organism|inhibition of killing of cells of another organism|negative regulation of killing of cells of another organism|down-regulation of killing of cells of another organism|negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051711 GO:0051712 biolink:BiologicalProcess positive regulation of killing of cells of other organism Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism. go-plus.json positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|upregulation of killing of cells of another organism|activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction|induction by organism of apoptosis in other organism involved in symbiotic interaction|stimulation of killing of cells of another organism|activation of killing of cells of another organism|up-regulation of killing of cells of another organism|positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction|enhancement of other organism programmed cell death by organism|positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction|induction by organism of apoptosis in other organism during symbiotic interaction|up regulation of killing of cells of another organism http://purl.obolibrary.org/obo/GO_0051712 GO:0051717 biolink:MolecularActivity inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate. Reactome:R-HSA-1855200|Reactome:R-HSA-1855205|MetaCyc:3.1.3.62-RXN go-plus.json inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity|inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity|inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity http://purl.obolibrary.org/obo/GO_0051717 GO:0051718 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA). Reactome:R-HSA-5334151 go-plus.json HpaII methylase|M.BsuRIb|M.BsuRIa|HpaII' methylase http://purl.obolibrary.org/obo/GO_0051718 GO:0051715 biolink:BiologicalProcess cytolysis in other organism The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm. go-plus.json cytolysis of cells of another organism|cytolysis of cells of competing organism|cytolysis of cells of another, non-host, organism http://purl.obolibrary.org/obo/GO_0051715 GO:0051716 biolink:BiologicalProcess cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051716 gocheck_do_not_manually_annotate GO:0051719 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN. Reactome:R-HSA-5334152|Reactome:R-HSA-5334097 go-plus.json http://purl.obolibrary.org/obo/GO_0051719 GO:0036156 biolink:CellularComponent inner dynein arm Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. go-plus.json inner dynein arm complex http://purl.obolibrary.org/obo/GO_0036156 GO:0036157 biolink:CellularComponent outer dynein arm Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. go-plus.json outer dynein arm complex http://purl.obolibrary.org/obo/GO_0036157 GO:0036158 biolink:BiologicalProcess outer dynein arm assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. go-plus.json ODA assembly http://purl.obolibrary.org/obo/GO_0036158 GO:0036159 biolink:BiologicalProcess inner dynein arm assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. go-plus.json IDA assembly http://purl.obolibrary.org/obo/GO_0036159 CHEBI:75231 biolink:ChemicalSubstance 12-oxo-ETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75231 chebi_ph7_3 CHEBI:90872 biolink:ChemicalSubstance L-thyroxine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90872 chebi_ph7_3 CHEBI:90873 biolink:ChemicalSubstance dehydroalanine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90873 chebi_ph7_3 CHEBI:75232 biolink:ChemicalSubstance (8R)-hydroxy-(11R,12R)-epoxyicosa-(5Z,9E,14Z)-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75232 chebi_ph7_3 GO:0036150 biolink:BiologicalProcess phosphatidylserine acyl-chain remodeling Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains. go-plus.json phosphatidyl-L-serine acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036150 CHEBI:90874 biolink:ChemicalSubstance 3,3',5-triiodo-L-thyronine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90874 chebi_ph7_3 GO:0036151 biolink:BiologicalProcess phosphatidylcholine acyl-chain remodeling Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. go-plus.json http://purl.obolibrary.org/obo/GO_0036151 CHEBI:75230 biolink:ChemicalSubstance 12(R)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75230 chebi_ph7_3 GO:0036152 biolink:BiologicalProcess phosphatidylethanolamine acyl-chain remodeling Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. go-plus.json http://purl.obolibrary.org/obo/GO_0036152 CHEBI:75235 biolink:ChemicalSubstance (13R)-hydroxy-(14S,15S)-epoxyicosa-(5Z,8Z,11Z)-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75235 chebi_ph7_3 GO:0036153 biolink:BiologicalProcess triglyceride acyl-chain remodeling Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains. go-plus.json triacylglycerol acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036153 GO:0036154 biolink:BiologicalProcess diacylglycerol acyl-chain remodeling Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains. go-plus.json diglyceride acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036154 CHEBI:90870 biolink:ChemicalSubstance 3-iodo-L-tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90870 chebi_ph7_3 CHEBI:75233 biolink:ChemicalSubstance (8R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,9E,14Z)-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75233 chebi_ph7_3 CHEBI:75234 biolink:ChemicalSubstance (10R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,8Z,14Z)-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75234 chebi_ph7_3 GO:0036155 biolink:BiologicalProcess acylglycerol acyl-chain remodeling Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains. go-plus.json glyceride acyl-chain remodeling http://purl.obolibrary.org/obo/GO_0036155 CHEBI:90871 biolink:ChemicalSubstance 3,5-diiodo-L-tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90871 chebi_ph7_3 GO:0051720 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG. go-plus.json http://purl.obolibrary.org/obo/GO_0051720 GO:0051721 biolink:MolecularActivity protein phosphatase 2A binding Binding to protein phosphatase 2A. go-plus.json protein phosphatase 2 binding http://purl.obolibrary.org/obo/GO_0051721 GO:0051724 biolink:MolecularActivity NAD transmembrane transporter activity Enables the transfer of NAD from one side of a membrane to the other. go-plus.json NADH transporter activity|NAD+ transporter activity|NAD (oxidized) transporter activity|oxidized nicotinamide adenine dinucleotide transmembrane transporter activity|NAD (reduced) transporter activity|oxidized NAD transporter activity|reduced nicotinamide adenine dinucleotide transmembrane transporter activity|reduced NAD transporter activity|nicotinamide adenine dinucleotide transmembrane transporter activity|NAD transporter activity http://purl.obolibrary.org/obo/GO_0051724 GO:0051725 biolink:BiologicalProcess protein de-ADP-ribosylation The process of removing one or more ADP-ribose residues from a protein. go-plus.json removal of ADP-ribose from protein|protein poly(ADP-ribose) catabolism|protein poly(ADP-ribose) degradation|protein poly(ADP-ribose) catabolic process|protein poly(ADP-ribose) hydrolysis|protein amino acid de-ADP-ribosylation|poly(ADP-ribose) removal from protein http://purl.obolibrary.org/obo/GO_0051725 GO:0051722 biolink:MolecularActivity protein C-terminal methylesterase activity Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol. Reactome:R-HSA-8856951 go-plus.json protein phosphatase methylesterase activity http://purl.obolibrary.org/obo/GO_0051722 GO:0051723 biolink:MolecularActivity protein methylesterase activity Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol. Reactome:R-HSA-5367022 go-plus.json PME activity|protein methyl-esterase activity|protein carboxylic ester hydrolase activity|protein carboxyl methylesterase activity http://purl.obolibrary.org/obo/GO_0051723 GO:0051728 biolink:BiologicalProcess cell cycle switching, mitotic to meiotic cell cycle The process in which a cell switches cell cycle mode from mitotic to meiotic division. go-plus.json cell cycle switching, mitosis to meiosis|initiation of meiosis|initiation of meiotic cell cycle|conversion to meiotic cell cycle|entry into meiosis|conversion to meiosis|entry into meiotic cell cycle|meiotic entry http://purl.obolibrary.org/obo/GO_0051728 GO:0051729 biolink:BiologicalProcess germline cell cycle switching, mitotic to meiotic cell cycle The process in which a germline cell switches cell cycle mode from mitotic to meiotic division. go-plus.json germline entry into meiotic cell cycle|germline cell cycle switching, mitosis to meiosis|germline conversion to meiosis|germline meiotic entry|germline initiation of meiotic cell cycle|germline initiation of meiosis|germline conversion to meiotic cell cycle|germline entry into meiosis http://purl.obolibrary.org/obo/GO_0051729 GO:0051726 biolink:BiologicalProcess regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle. go-plus.json cell cycle arrest|cell cycle regulation|arrest of mitotic cell cycle progression|regulation of progression through cell cycle|mitotic cell cycle arrest|regulation of cell cycle progression|cell cycle modulation|regulation of cell cycle arrest|positive regulation of cell cycle arrest|control of cell cycle progression|modulation of cell cycle progression|negative regulation of cell cycle arrest|cell cycle regulator|tumor suppressor http://purl.obolibrary.org/obo/GO_0051726 goslim_yeast GO:0051727 biolink:BiologicalProcess obsolete cell cycle switching, meiotic to mitotic cell cycle OBSOLETE. The process in which a cell switches cell cycle mode from meiotic to mitotic division. go-plus.json entry into mitotic cell cycle|cell cycle switching, meiotic to mitotic cell cycle|entry into mitosis|initiation of mitotic cell cycle|cell cycle switching, meiosis to mitosis|conversion to mitosis|mitotic entry|conversion to mitotic cell cycle|initiation of mitosis http://purl.obolibrary.org/obo/GO_0051727 CHEBI:145470 biolink:ChemicalSubstance sophoroside go-plus.json http://purl.obolibrary.org/obo/CHEBI_145470 chebi_ph7_3 GO:0036145 biolink:BiologicalProcess dendritic cell homeostasis The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json DC homeostasis http://purl.obolibrary.org/obo/GO_0036145 CHEBI:90869 biolink:ChemicalSubstance validamycin A(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90869 chebi_ph7_3 GO:0036146 biolink:BiologicalProcess cellular response to mycotoxin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0036146 GO:0036147 biolink:BiologicalProcess rumination A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again. go-plus.json digestive rumination http://purl.obolibrary.org/obo/GO_0036147 GO:0036148 biolink:BiologicalProcess phosphatidylglycerol acyl-chain remodeling Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains. go-plus.json http://purl.obolibrary.org/obo/GO_0036148 GO:0036149 biolink:BiologicalProcess phosphatidylinositol acyl-chain remodeling Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains. go-plus.json http://purl.obolibrary.org/obo/GO_0036149 CHEBI:90866 biolink:ChemicalSubstance 14-HDoHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90866 chebi_ph7_3 CHEBI:90867 biolink:ChemicalSubstance 14-oxo-DoHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90867 chebi_ph7_3 CHEBI:90868 biolink:ChemicalSubstance validamycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_90868 chebi_ph7_3 CHEBI:75242 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75242 chebi_ph7_3 CHEBI:75243 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75243 chebi_ph7_3 CHEBI:90862 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90862 chebi_ph7_3 CHEBI:75240 biolink:ChemicalSubstance 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75240 chebi_ph7_3 GO:0036140 biolink:MolecularActivity peptidyl-asparagine 3-dioxygenase activity Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2. go-plus.json http://purl.obolibrary.org/obo/GO_0036140 CHEBI:75241 biolink:ChemicalSubstance 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75241 chebi_ph7_3 GO:0036141 biolink:MolecularActivity L-phenylalanine-oxaloacetate transaminase activity Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate. go-plus.json L-phenylalanine:oxaloacetate transaminase activity http://purl.obolibrary.org/obo/GO_0036141 GO:0036142 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036142 CHEBI:75244 biolink:ChemicalSubstance aklaviketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75244 GO:0036143 biolink:MolecularActivity kringle domain binding Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors. go-plus.json http://purl.obolibrary.org/obo/GO_0036143 CHEBI:75245 biolink:ChemicalSubstance 1-O-octadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75245 chebi_ph7_3 GO:0036144 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036144 GO:0051731 biolink:MolecularActivity polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. go-plus.json PNK|5'-dephosphopolynucleotide kinase activity|polynucleotide kinase activity|polynucleotide 5'-hydroxy-kinase activity|polynucleotide 5'-hydroxyl kinase (phosphorylating) activity|5'-hydroxyl polynucleotide kinase activity http://purl.obolibrary.org/obo/GO_0051731 GO:0051732 biolink:MolecularActivity polyribonucleotide kinase activity Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA. go-plus.json RNA 5'-hydroxyl kinase activity|5'-hydroxyl RNA kinase activity|5'-hydroxyl polyribonucleotide kinase activity|RNA kinase activity http://purl.obolibrary.org/obo/GO_0051732 GO:0051730 biolink:MolecularActivity GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA. go-plus.json GTP-dependent RNA kinase activity|GTP-dependent polyribonucleotide kinase activity|GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent RNA 5'-hydroxyl-kinase activity http://purl.obolibrary.org/obo/GO_0051730 GO:0051735 biolink:MolecularActivity GTP-dependent polynucleotide kinase activity Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. go-plus.json GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0051735 GO:0051736 biolink:MolecularActivity polyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA. go-plus.json ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|ATP-dependent RNA 5'-hydroxyl-kinase activity|ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity|ATP-dependent RNA kinase activity|ATP-dependent polyribonucleotide kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity http://purl.obolibrary.org/obo/GO_0051736 GO:0051733 biolink:MolecularActivity polydeoxyribonucleotide kinase activity Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA. go-plus.json DNA kinase activity|DNA 5'-hydroxyl kinase activity http://purl.obolibrary.org/obo/GO_0051733 GO:0051734 biolink:MolecularActivity polynucleotide kinase activity Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. EC:2.7.1.78|RHEA:54580 go-plus.json ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP:5'-dephosphopolynucleotide 5'-phosphatase activity|ATP-dependent polynucleotide kinase activity http://purl.obolibrary.org/obo/GO_0051734 GO:0075705 biolink:BiologicalProcess obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. go-plus.json viral penetration via endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane http://purl.obolibrary.org/obo/GO_0075705 GO:0075706 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075706 GO:0051739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051739 GO:0051737 biolink:MolecularActivity GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA. go-plus.json GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity|GTP-dependent DNA 5'-hydroxyl-kinase activity|GTP-dependent DNA kinase activity|GTP-dependent polydeoxyribonucleotide kinase activity http://purl.obolibrary.org/obo/GO_0051737 GO:0051738 biolink:MolecularActivity xanthophyll binding Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen. go-plus.json http://purl.obolibrary.org/obo/GO_0051738 GO:0036134 biolink:MolecularActivity 12-hydroxyheptadecatrienoic acid synthase activity Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA). RHEA:48644|Reactome:R-HSA-2161613 go-plus.json prostaglandin H2 degradation activity http://purl.obolibrary.org/obo/GO_0036134 GO:0036135 biolink:BiologicalProcess Schwann cell migration The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function. go-plus.json http://purl.obolibrary.org/obo/GO_0036135 GO:0036136 biolink:MolecularActivity kynurenine-oxaloacetate transaminase activity Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate. go-plus.json L-kynurenine-oxaloacetate transaminase activity http://purl.obolibrary.org/obo/GO_0036136 GO:0036137 biolink:MolecularActivity kynurenine aminotransferase activity Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid. go-plus.json kynurenine-oxo-acid transaminase activity|L-kynurenine transaminase activity http://purl.obolibrary.org/obo/GO_0036137 GO:0036138 biolink:BiologicalProcess peptidyl-histidine hydroxylation The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine. go-plus.json http://purl.obolibrary.org/obo/GO_0036138 CHEBI:90898 biolink:ChemicalSubstance protoviolaceinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90898 chebi_ph7_3 CHEBI:90899 biolink:ChemicalSubstance violaceinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90899 GO:0036139 biolink:MolecularActivity peptidyl-histidine dioxygenase activity Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2. go-plus.json http://purl.obolibrary.org/obo/GO_0036139 CHEBI:90894 biolink:ChemicalSubstance (-)-5'-desmethylyatein go-plus.json http://purl.obolibrary.org/obo/CHEBI_90894 chebi_ph7_3 CHEBI:90896 biolink:ChemicalSubstance (-)-pluviatolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90896 chebi_ph7_3 CHEBI:90897 biolink:ChemicalSubstance protoviolaceinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90897 GO:0036130 biolink:MolecularActivity prostaglandin H2 endoperoxidase reductase activity Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate). RHEA:45312|KEGG_REACTION:R02264|Reactome:R-HSA-2161549 go-plus.json PGH2 9-,11-endoperoxide reductase|PGH2 9,11-endoperoxidase http://purl.obolibrary.org/obo/GO_0036130 CHEBI:75257 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75257 chebi_ph7_3 CHEBI:90890 biolink:ChemicalSubstance 3-farnesyl-3-hydroxy-2-methyl-1-oxo-1lambda(5)-quinolin-4-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_90890 chebi_ph7_3 GO:0036131 biolink:MolecularActivity prostaglandin D2 11-ketoreductase activity Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+. Reactome:R-HSA-2161614|EC:1.1.1.188|RHEA:45316|KEGG_REACTION:R02799 go-plus.json PGD2 11-ketoreductase|prostaglandin 11-keto reductase http://purl.obolibrary.org/obo/GO_0036131 CHEBI:90891 biolink:ChemicalSubstance 2-imino-3-(indol-3-yl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90891 GO:0036132 biolink:MolecularActivity 13-prostaglandin reductase activity Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin. KEGG_REACTION:R04557|KEGG_REACTION:R04556|EC:1.3.1.48|Reactome:R-HSA-2161692 go-plus.json 15-oxo-delta13-prostaglandin reductase activity|15-oxoprostaglandin 13-reductase activity|prostaglandin delta13-reductase activity|prostaglandin 13-reductase activity|15-ketoprostaglandin delta13-reductase activity|delta13-15-ketoprostaglandin reductase activity http://purl.obolibrary.org/obo/GO_0036132 CHEBI:75255 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75255 chebi_ph7_3 CHEBI:90892 biolink:ChemicalSubstance 2-imino-3-(indol-3-yl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90892 GO:0036133 biolink:MolecularActivity 11-hydroxythromboxane B2 dehydrogenase activity Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+. Reactome:R-HSA-2161732|KEGG_REACTION:R05060|RHEA:52312 go-plus.json NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity http://purl.obolibrary.org/obo/GO_0036133 CHEBI:90893 biolink:ChemicalSubstance (-)-bursehernin go-plus.json http://purl.obolibrary.org/obo/CHEBI_90893 chebi_ph7_3 CHEBI:75256 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75256 chebi_ph7_3 GO:0051742 biolink:MolecularActivity 2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine. MetaCyc:RXN-2762|RHEA:37999 go-plus.json MSBQ methyltransferase activity http://purl.obolibrary.org/obo/GO_0051742 GO:0051743 biolink:MolecularActivity red chlorophyll catabolite reductase activity Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence. MetaCyc:RXN-7741|RHEA:24752 go-plus.json RCC reductase activity http://purl.obolibrary.org/obo/GO_0051743 GO:0051740 biolink:MolecularActivity ethylene binding Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. go-plus.json ethene binding http://purl.obolibrary.org/obo/GO_0051740 GO:0051741 biolink:MolecularActivity 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine. MetaCyc:RXN-2542|RHEA:37979 go-plus.json MPBQ methyltransferase activity http://purl.obolibrary.org/obo/GO_0051741 GO:0051746 biolink:MolecularActivity thalianol synthase activity Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol). EC:5.4.99.31|RHEA:26160 go-plus.json http://purl.obolibrary.org/obo/GO_0051746 GO:0051747 biolink:MolecularActivity cytosine C-5 DNA demethylase activity Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA. go-plus.json DNA methyltransferase activity acting on cytosine C-5|hydrolytic DNA demethylase activity|DNA demethylase activity http://purl.obolibrary.org/obo/GO_0051747 CHEBI:89891 biolink:ChemicalSubstance 3-hexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_89891 chebi_ph7_3 GO:0051744 biolink:MolecularActivity 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+. MetaCyc:RXN1F-72|RHEA:48884 go-plus.json http://purl.obolibrary.org/obo/GO_0051744 GO:0051745 biolink:MolecularActivity 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. MetaCyc:ISPH2-RXN|EC:1.17.7.4 go-plus.json 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity|isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051745 GO:0051748 biolink:MolecularActivity UTP-monosaccharide-1-phosphate uridylyltransferase activity Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide. MetaCyc:2.7.7.64-RXN|RHEA:13205|EC:2.7.7.64 go-plus.json UDP-monosaccharide pyrophosphorylase activity|UDP-monosaccharide diphosphorylase activity|USP|PsUSP|UDP-sugar pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0051748 GO:0051749 biolink:MolecularActivity indole acetic acid carboxyl methyltransferase activity Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine. go-plus.json IAA carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0051749 PR:000013429 biolink:Protein parathyroid hormone A protein that is a translation product of the human PTH gene or a 1:1 ortholog thereof. go-plus.json parathyrin|parathormone|PTH http://purl.obolibrary.org/obo/PR_000013429 GO:0036123 biolink:BiologicalProcess histone H3-K9 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone. go-plus.json histone H3 K9 dimethylation|histone lysine H3 K9 dimethylation http://purl.obolibrary.org/obo/GO_0036123 GO:0036124 biolink:BiologicalProcess histone H3-K9 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0036124 GO:0036125 biolink:CellularComponent fatty acid beta-oxidation multienzyme complex A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT). go-plus.json http://purl.obolibrary.org/obo/GO_0036125 GO:0036126 biolink:CellularComponent sperm flagellum A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid. go-plus.json sperm cilium|sperm tail http://purl.obolibrary.org/obo/GO_0036126 GO:0036127 biolink:MolecularActivity 3-sulfino-L-alanine binding Binding to 3-sulfino-L-alanine (cysteine sulfinate). go-plus.json cysteine sulfinate binding http://purl.obolibrary.org/obo/GO_0036127 CHEBI:90887 biolink:ChemicalSubstance 2-hydroxy-6-oxo-2,4-heptadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90887 chebi_ph7_3 GO:0036128 biolink:CellularComponent CatSper complex A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits. go-plus.json CatSper channel complex|CATSPER channel http://purl.obolibrary.org/obo/GO_0036128 CHEBI:90888 biolink:ChemicalSubstance aurachin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_90888 chebi_ph7_3 GO:0036129 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036129 CHEBI:90889 biolink:ChemicalSubstance aurachin C epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90889 chebi_ph7_3 CHEBI:75264 biolink:ChemicalSubstance 1-acyl-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75264 chebi_ph7_3 CHEBI:90883 biolink:ChemicalSubstance 2,3-dichloromuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90883 chebi_ph7_3 CHEBI:90884 biolink:ChemicalSubstance 2'-hydroxyrifampicin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90884 chebi_ph7_3 CHEBI:75265 biolink:ChemicalSubstance 1-acyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75265 chebi_ph7_3 CHEBI:90885 biolink:ChemicalSubstance 1,3,7-trimethyl-5-hydroxyisouric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90885 chebi_ph7_3 CHEBI:90886 biolink:ChemicalSubstance 2-hydroxy-6-oxo-2,4-heptadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90886 CHEBI:75263 biolink:ChemicalSubstance 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75263 chebi_ph7_3 CHEBI:75268 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_75268 chebi_ph7_3 GO:0036120 biolink:BiologicalProcess cellular response to platelet-derived growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. go-plus.json cellular response to PDGF stimulus http://purl.obolibrary.org/obo/GO_0036120 GO:0036121 biolink:MolecularActivity double-stranded DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix. go-plus.json double-stranded DNA-dependent ATP-dependent DNA helicase activity|dsDNA-dependent ATPase activity|double-stranded DNA-dependent ATPase activity|dsDNA-dependent ATP-dependent DNA helicase activity http://purl.obolibrary.org/obo/GO_0036121 CHEBI:75266 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75266 chebi_ph7_3 CHEBI:90882 biolink:ChemicalSubstance 3,4-dichlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90882 chebi_ph7_3 GO:0036122 biolink:MolecularActivity BMP binding Binding to a member of the bone morphogenetic protein (BMP) family. go-plus.json bone morphogenetic protein binding http://purl.obolibrary.org/obo/GO_0036122 NCBITaxon:4932 biolink:OrganismalEntity Saccharomyces cerevisiae go-plus.json Saccharomyces uvarum var. melibiosus|baker's yeast|brewer's yeast|Mycoderma cerevisiae|Saccharomyces oviformis|Saccharomyces italicus|S. cerevisiae|Candida robusta|Saccharomyces capensis http://purl.obolibrary.org/obo/NCBITaxon_4932 NCBITaxon:4930 biolink:OrganismalEntity Saccharomyces go-plus.json Pachytichospora http://purl.obolibrary.org/obo/NCBITaxon_4930 CHEBI:16858 biolink:ChemicalSubstance pantetheine 4'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16858 CHEBI:16859 biolink:ChemicalSubstance oxaloacetic acid 4-methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_16859 CHEBI:16856 biolink:ChemicalSubstance glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16856 CHEBI:16857 biolink:ChemicalSubstance L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16857 GO:0002908 biolink:BiologicalProcess regulation of peripheral B cell deletion Any process that modulates the frequency, rate, or extent of peripheral B cell deletion. go-plus.json http://purl.obolibrary.org/obo/GO_0002908 CHEBI:16854 biolink:ChemicalSubstance 3-fumarylpyruvate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16854 chebi_ph7_3 GO:0002909 biolink:BiologicalProcess negative regulation of peripheral B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion. go-plus.json down-regulation of peripheral B cell deletion|downregulation of peripheral B cell deletion|down regulation of peripheral B cell deletion|inhibition of peripheral B cell deletion http://purl.obolibrary.org/obo/GO_0002909 CHEBI:16855 biolink:ChemicalSubstance D-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16855 CHEBI:16852 biolink:ChemicalSubstance L-dopaquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16852 CHEBI:16853 biolink:ChemicalSubstance tetrathionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16853 GO:0002904 biolink:BiologicalProcess positive regulation of B cell apoptotic process Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process. go-plus.json up regulation of B cell apoptosis|upregulation of B cell apoptosis|stimulation of B cell apoptosis|activation of B cell apoptosis|up-regulation of B cell apoptosis|positive regulation of B cell apoptosis http://purl.obolibrary.org/obo/GO_0002904 CHEBI:16850 biolink:ChemicalSubstance 1,2-dihydro-alpha-santonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16850 chebi_ph7_3 GO:0002905 biolink:BiologicalProcess regulation of mature B cell apoptotic process Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process. go-plus.json regulation of mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002905 CHEBI:16851 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16851 GO:0002906 biolink:BiologicalProcess negative regulation of mature B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process. go-plus.json down-regulation of mature B cell apoptosis|inhibition of mature B cell apoptosis|down regulation of mature B cell apoptosis|downregulation of mature B cell apoptosis|negative regulation of mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002906 GO:0002907 biolink:BiologicalProcess positive regulation of mature B cell apoptotic process Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process. go-plus.json activation of mature B cell apoptosis|stimulation of mature B cell apoptosis|up-regulation of mature B cell apoptosis|upregulation of mature B cell apoptosis|positive regulation of mature B cell apoptosis|up regulation of mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002907 GO:0002900 biolink:BiologicalProcess positive regulation of central B cell deletion Any process that activates or increases the frequency, rate, or extent of central B cell deletion. go-plus.json up regulation of central B cell deletion|activation of central B cell deletion|stimulation of central B cell deletion|up-regulation of central B cell deletion|upregulation of central B cell deletion http://purl.obolibrary.org/obo/GO_0002900 GO:0002901 biolink:BiologicalProcess mature B cell apoptotic process Any apoptotic process in a B cell that is mature, having left the bone marrow. go-plus.json apoptosis of mature B-lymphocytes|apoptosis of mature B-cells|mature B lymphocyte programmed cell death by apoptosis|mature B lymphocyte apoptosis|programmed cell death of mature B-cells by apoptosis|mature B cell programmed cell death by apoptosis|programmed cell death, mature B lymphocytes|programmed cell death of mature B-lymphocytes by apoptosis|programmed cell death, mature B cells|mature B-lymphocyte programmed cell death by apoptosis|apoptosis of mature B lymphocytes|programmed cell death of mature B cells by apoptosis|mature B-cell apoptosis|mature B-cell programmed cell death by apoptosis|apoptosis of mature B cells|programmed cell death, mature B-lymphocytes|mature B-lymphocyte apoptosis|programmed cell death of mature B lymphocytes by apoptosis|programmed cell death, mature B-cells|mature B cell apoptosis http://purl.obolibrary.org/obo/GO_0002901 GO:0002902 biolink:BiologicalProcess regulation of B cell apoptotic process Any process that modulates the frequency, rate, or extent of B cell apoptotic process. go-plus.json regulation of B cell apoptosis http://purl.obolibrary.org/obo/GO_0002902 GO:0002903 biolink:BiologicalProcess negative regulation of B cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process. go-plus.json downregulation of B cell apoptosis|down regulation of B cell apoptosis|inhibition of B cell apoptosis|negative regulation of B cell apoptosis|down-regulation of B cell apoptosis http://purl.obolibrary.org/obo/GO_0002903 GO:0002910 biolink:BiologicalProcess positive regulation of peripheral B cell deletion Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion. go-plus.json upregulation of peripheral B cell deletion|stimulation of peripheral B cell deletion|up-regulation of peripheral B cell deletion|activation of peripheral B cell deletion|up regulation of peripheral B cell deletion http://purl.obolibrary.org/obo/GO_0002910 CHEBI:16849 biolink:ChemicalSubstance D-fructuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16849 CHEBI:16848 biolink:ChemicalSubstance coenzyme gamma-F420-2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_16848 CHEBI:16845 biolink:ChemicalSubstance (S)-2,3,4,5-tetrahydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16845 chebi_ph7_3 CHEBI:16846 biolink:ChemicalSubstance UDP-alpha-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16846 GO:0002919 biolink:BiologicalProcess positive regulation of peripheral B cell anergy Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy. go-plus.json up regulation of peripheral B cell anergy|upregulation of peripheral B cell anergy|stimulation of peripheral B cell anergy|up-regulation of peripheral B cell anergy|activation of peripheral B cell anergy http://purl.obolibrary.org/obo/GO_0002919 CHEBI:16843 biolink:ChemicalSubstance cis-1,2-dihydro-3-ethylcatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16843 chebi_ph7_3 CHEBI:16844 biolink:ChemicalSubstance N(3')-acetyl-2-deoxystreptamine antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_16844 CHEBI:16841 biolink:ChemicalSubstance bis(3-aminopropyl)amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16841 CHEBI:16842 biolink:ChemicalSubstance formaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16842 chebi_ph7_3 GO:0002915 biolink:BiologicalProcess negative regulation of central B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy. go-plus.json inhibition of central B cell anergy|down regulation of central B cell anergy|downregulation of central B cell anergy|down-regulation of central B cell anergy http://purl.obolibrary.org/obo/GO_0002915 GO:0002916 biolink:BiologicalProcess positive regulation of central B cell anergy Any process that activates or increases the frequency, rate, or extent of central B cell anergy. go-plus.json up-regulation of central B cell anergy|upregulation of central B cell anergy|up regulation of central B cell anergy|activation of central B cell anergy|stimulation of central B cell anergy http://purl.obolibrary.org/obo/GO_0002916 CHEBI:16840 biolink:ChemicalSubstance 4-CDP-2-C-methyl-D-erythritol 2-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16840 GO:0002917 biolink:BiologicalProcess regulation of peripheral B cell anergy Any process that modulates the frequency, rate, or extent of peripheral B cell anergy. go-plus.json http://purl.obolibrary.org/obo/GO_0002917 GO:0002918 biolink:BiologicalProcess negative regulation of peripheral B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy. go-plus.json downregulation of peripheral B cell anergy|down regulation of peripheral B cell anergy|inhibition of peripheral B cell anergy|down-regulation of peripheral B cell anergy http://purl.obolibrary.org/obo/GO_0002918 GO:0002911 biolink:BiologicalProcess regulation of lymphocyte anergy Any process that modulates the frequency, rate, or extent of lymphocyte anergy. go-plus.json http://purl.obolibrary.org/obo/GO_0002911 GO:0002912 biolink:BiologicalProcess negative regulation of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy. go-plus.json down regulation of lymphocyte anergy|downregulation of lymphocyte anergy|down-regulation of lymphocyte anergy|inhibition of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002912 GO:0002913 biolink:BiologicalProcess positive regulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy. go-plus.json up regulation of lymphocyte anergy|activation of lymphocyte anergy|stimulation of lymphocyte anergy|up-regulation of lymphocyte anergy|upregulation of lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002913 GO:0002914 biolink:BiologicalProcess regulation of central B cell anergy Any process that modulates the frequency, rate, or extent of central B cell anergy. go-plus.json http://purl.obolibrary.org/obo/GO_0002914 CHEBI:16878 biolink:ChemicalSubstance N-acetyl-L-gamma-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16878 CHEBI:16879 biolink:ChemicalSubstance diethyl 2-methyl-3-oxosuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16879 chebi_ph7_3 CHEBI:16877 biolink:ChemicalSubstance oxidized Watasenia luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16877 CHEBI:16874 biolink:ChemicalSubstance psychosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16874 CHEBI:16875 biolink:ChemicalSubstance 5,6-dihydroxyindole-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16875 chebi_ph7_3 CHEBI:16872 biolink:ChemicalSubstance N-malonylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16872 chebi_ph7_3 CHEBI:16870 biolink:ChemicalSubstance choline alfoscerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16870 chebi_ph7_3 CHEBI:16871 biolink:ChemicalSubstance 4-pyridoxolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16871 chebi_ph7_3 CHEBI:41808 biolink:ChemicalSubstance decane go-plus.json http://purl.obolibrary.org/obo/CHEBI_41808 chebi_ph7_3 CHEBI:41805 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_41805 CHEBI:16869 biolink:ChemicalSubstance oleandomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16869 CHEBI:16867 biolink:ChemicalSubstance D-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16867 CHEBI:16865 biolink:ChemicalSubstance gamma-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16865 CHEBI:16866 biolink:ChemicalSubstance alizarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16866 chebi_ph7_3 CHEBI:16863 biolink:ChemicalSubstance 6-phospho-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16863 CHEBI:16864 biolink:ChemicalSubstance D-ribofuranosyl-ADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16864 CHEBI:16861 biolink:ChemicalSubstance 7''-O-phosphohygromycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_16861 CHEBI:16862 biolink:ChemicalSubstance nucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16862 CHEBI:16860 biolink:ChemicalSubstance 3',4',5,7-tetrahydroxy-3-methoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16860 CHEBI:16818 biolink:ChemicalSubstance all-trans-pentaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16818 CHEBI:16816 biolink:ChemicalSubstance flavonol 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16816 chebi_ph7_3 CHEBI:16817 biolink:ChemicalSubstance trans-4-hydroxycyclohexanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16817 CHEBI:16814 biolink:ChemicalSubstance dehydroepiandrosterone sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16814 CHEBI:16815 biolink:ChemicalSubstance enol-phenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16815 chebi_ph7_3 CHEBI:16812 biolink:ChemicalSubstance (S,S)-butane-2,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16812 chebi_ph7_3 CHEBI:16813 biolink:ChemicalSubstance galactitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16813 chebi_ph7_3 CHEBI:16810 biolink:ChemicalSubstance 2-oxoglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16810 chebi_ph7_3 CHEBI:16811 biolink:ChemicalSubstance methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16811 CHEBI:16809 biolink:ChemicalSubstance D-glucose 6-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16809 CHEBI:16807 biolink:ChemicalSubstance S(6)-acetyldihydrolipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16807 chebi_ph7_3 CHEBI:16808 biolink:ChemicalSubstance 2-dehydro-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16808 chebi_ph7_3 CHEBI:16805 biolink:ChemicalSubstance [1-(5-phosphoribosyl)imidazol-4-yl]acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16805 CHEBI:16806 biolink:ChemicalSubstance xanthine-8-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16806 chebi_ph7_3 CHEBI:16803 biolink:ChemicalSubstance N-acetylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16803 chebi_ph7_3 CHEBI:16804 biolink:ChemicalSubstance (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16804 CHEBI:16802 biolink:ChemicalSubstance sedoheptulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16802 chebi_ph7_3 NCBITaxon:4951 biolink:OrganismalEntity Yarrowia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4951 NCBITaxon:4952 biolink:OrganismalEntity Yarrowia lipolytica go-plus.json Mycotorula lipolytica|Candida lipolytica|Endomycopsis lipolytica http://purl.obolibrary.org/obo/NCBITaxon_4952 CHEBI:16838 biolink:ChemicalSubstance polyphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16838 chebi_ph7_3 CHEBI:90814 biolink:ChemicalSubstance 17(R)-HDoHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90814 chebi_ph7_3 CHEBI:16836 biolink:ChemicalSubstance 4-nitrophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16836 CHEBI:90815 biolink:ChemicalSubstance (4Z,7Z,10Z,14E,16Z,19Z)-13-hydroxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90815 chebi_ph7_3 CHEBI:16837 biolink:ChemicalSubstance alpha-ribazole 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16837 CHEBI:16834 biolink:ChemicalSubstance L-gamma-glutamyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16834 CHEBI:89823 biolink:ChemicalSubstance PS(16:0/18:2(9Z,12Z)) go-plus.json http://purl.obolibrary.org/obo/CHEBI_89823 CHEBI:16835 biolink:ChemicalSubstance 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16835 CHEBI:90810 biolink:ChemicalSubstance 5(S),11(R)-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90810 chebi_ph7_3 CHEBI:16832 biolink:ChemicalSubstance kievitone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16832 chebi_ph7_3 CHEBI:90811 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90811 chebi_ph7_3 CHEBI:16833 biolink:ChemicalSubstance neurosporene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16833 chebi_ph7_3 CHEBI:90812 biolink:ChemicalSubstance 5(S),15(R)-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90812 chebi_ph7_3 CHEBI:16830 biolink:ChemicalSubstance methylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16830 CHEBI:90813 biolink:ChemicalSubstance 5(S),15(S)-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90813 chebi_ph7_3 CHEBI:89828 biolink:ChemicalSubstance propyl propionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_89828 chebi_ph7_3 CHEBI:16831 biolink:ChemicalSubstance 3-hydroxy-3-methylglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16831 GO:0051900 biolink:BiologicalProcess regulation of mitochondrial depolarization Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. go-plus.json http://purl.obolibrary.org/obo/GO_0051900 GO:0051901 biolink:BiologicalProcess positive regulation of mitochondrial depolarization Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. go-plus.json upregulation of mitochondrial depolarization|stimulation of mitochondrial depolarization|up-regulation of mitochondrial depolarization|activation of mitochondrial depolarization|up regulation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0051901 GO:0051904 biolink:BiologicalProcess pigment granule transport The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json pigment granule translocation http://purl.obolibrary.org/obo/GO_0051904 GO:0051905 biolink:BiologicalProcess establishment of pigment granule localization The directed movement of a pigment granule to a specific location. go-plus.json establishment of pigment granule localisation http://purl.obolibrary.org/obo/GO_0051905 GO:0051902 biolink:BiologicalProcess negative regulation of mitochondrial depolarization Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. go-plus.json down regulation of mitochondrial depolarization|inhibition of mitochondrial depolarization|down-regulation of mitochondrial depolarization|downregulation of mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0051902 GO:0051903 biolink:MolecularActivity S-(hydroxymethyl)glutathione dehydrogenase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+. KEGG_REACTION:R06983|Reactome:R-HSA-5692237|KEGG_REACTION:R07140|EC:1.1.1.284|MetaCyc:RXN-2962|UM-BBD_reactionID:r1146 go-plus.json chi-ADH activity|glutathione-dependent formaldehyde dehydrogenase activity|NAD-linked formaldehyde dehydrogenase activity|NAD- and glutathione-dependent formaldehyde dehydrogenase activity|class III alcohol dehydrogenase activity|ADH3 activity|GD-FALDH activity|S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity|GS-FDH activity|FDH activity|formic dehydrogenase activity|NAD-dependent formaldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0051903 GO:0051908 biolink:MolecularActivity double-stranded DNA 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule. go-plus.json double-stranded DNA specific 5'-3' exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0051908 CHEBI:16829 biolink:ChemicalSubstance polyneuridine aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16829 chebi_ph7_3 GO:0051909 biolink:MolecularActivity acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O. EC:4.2.1.27 go-plus.json alkynoate hydratase activity|3-hydroxypropenoate dehydratase activity|acetylenemonocarboxylate hydratase activity|acetylenecarboxylate hydratase activity http://purl.obolibrary.org/obo/GO_0051909 GO:0051906 biolink:BiologicalProcess maintenance of pigment granule location Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere. go-plus.json maintenance of pigment granule localization http://purl.obolibrary.org/obo/GO_0051906 CHEBI:16827 biolink:ChemicalSubstance corticosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16827 chebi_ph7_3 GO:0051907 biolink:MolecularActivity S-(hydroxymethyl)glutathione synthase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione. UM-BBD_reactionID:r1145|EC:4.4.1.22|RHEA:22488|KEGG_REACTION:R06982|MetaCyc:RXN-2961 go-plus.json glutathione-dependent formaldehyde-activating enzyme activity|S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)|Gfa|S-(hydroxymethyl)glutathione formaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0051907 CHEBI:16828 biolink:ChemicalSubstance L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_16828 CHEBI:90803 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90803 chebi_ph7_3 CHEBI:16825 biolink:ChemicalSubstance (R)-2-methylimino-1-phenylpropan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16825 chebi_ph7_3 CHEBI:16826 biolink:ChemicalSubstance acyl monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16826 CHEBI:16823 biolink:ChemicalSubstance kanamycin A 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16823 CHEBI:16824 biolink:ChemicalSubstance D-fuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16824 CHEBI:16821 biolink:ChemicalSubstance 4-oxo-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16821 CHEBI:16822 biolink:ChemicalSubstance choline sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16822 chebi_ph7_3 CHEBI:90800 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90800 chebi_ph7_3 CHEBI:90801 biolink:ChemicalSubstance 19-hydroxyprostaglandin H1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90801 chebi_ph7_3 CHEBI:90802 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90802 chebi_ph7_3 CHEBI:16820 biolink:ChemicalSubstance N-benzoyl-D-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16820 GO:0061280 biolink:BiologicalProcess epithelial cell migration involved in mesonephric proximal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0061280 GO:0061281 biolink:BiologicalProcess specification of mesonephric connecting tubule identity The process in which the connecting tubule of the mesonephric nephron acquires its identity. go-plus.json specification of mesonephric collecting tubule identity http://purl.obolibrary.org/obo/GO_0061281 GO:0061282 biolink:BiologicalProcess specification of mesonephric nephron tubule identity The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0061282 CHEBI:26267 biolink:ChemicalSubstance proanthocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26267 GO:0061283 biolink:BiologicalProcess specification of mesonephric distal tubule identity The process in which the distal tubule of the mesonephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0061283 GO:0061284 biolink:BiologicalProcess specification of mesonephric proximal tubule identity The process in which the proximal tubule of the mesonephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0061284 GO:0061285 biolink:BiologicalProcess mesonephric capsule development The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0061285 GO:0061286 biolink:BiologicalProcess mesonephric capsule morphogenesis The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go-plus.json http://purl.obolibrary.org/obo/GO_0061286 GO:0061287 biolink:BiologicalProcess mesonephric capsule formation The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go-plus.json http://purl.obolibrary.org/obo/GO_0061287 GO:0061288 biolink:BiologicalProcess mesonephric capsule specification The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0061288 GO:0061289 biolink:BiologicalProcess Wnt signaling pathway involved in kidney development The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time. go-plus.json Wnt receptor signalling pathway involved in kidney development|Wnt-activated signaling pathway involved in kidney development|Wnt receptor signaling pathway involved in kidney development http://purl.obolibrary.org/obo/GO_0061289 CHEBI:9407 biolink:ChemicalSubstance taurochenodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_9407 chebi_ph7_3 CHEBI:9402 biolink:ChemicalSubstance taraxerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_9402 chebi_ph7_3 CHEBI:26279 biolink:ChemicalSubstance propan-1-ols go-plus.json http://purl.obolibrary.org/obo/CHEBI_26279 CHEBI:51214 biolink:ChemicalSubstance diamminedichloroplatinum go-plus.json http://purl.obolibrary.org/obo/CHEBI_51214 GO:0061270 biolink:BiologicalProcess mesonephric intraglomerular mesangial cell proliferation The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0061270 GO:0061271 biolink:BiologicalProcess mesenchymal to epithelial transition involved in mesonephric renal vesicle formation A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0061271 GO:0061272 biolink:BiologicalProcess mesonephric connecting tubule development The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. go-plus.json mesonephric collecting tubule development|mesonephric connecting duct development http://purl.obolibrary.org/obo/GO_0061272 CHEBI:41893 biolink:ChemicalSubstance 4-deoxy-Delta(4)-beta-D-GlcpA go-plus.json http://purl.obolibrary.org/obo/CHEBI_41893 GO:0061273 biolink:BiologicalProcess mesonephric distal tubule morphogenesis The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061273 CHEBI:26271 biolink:ChemicalSubstance proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_26271 GO:0061274 biolink:BiologicalProcess mesonephric distal tubule development The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061274 GO:0061275 biolink:BiologicalProcess mesonephric proximal tubule development The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061275 CHEBI:26273 biolink:ChemicalSubstance proline derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_26273 GO:0061276 biolink:BiologicalProcess mesonephric proximal tubule morphogenesis The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061276 GO:0061277 biolink:BiologicalProcess mesonephric nephron tubule formation The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061277 GO:0061278 biolink:BiologicalProcess epithelial cell migration involved in mesonephric nephron tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0061278 GO:0061279 biolink:BiologicalProcess epithelial cell migration involved in mesonephric distal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0061279 CHEBI:9410 biolink:ChemicalSubstance taurodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9410 CHEBI:26248 biolink:ChemicalSubstance prenyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_26248 chebi_ph7_3 CHEBI:26249 biolink:ChemicalSubstance prenyl groups go-plus.json http://purl.obolibrary.org/obo/CHEBI_26249 CHEBI:26244 biolink:ChemicalSubstance prenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_26244 NCBITaxon:265488 biolink:OrganismalEntity Rhodopirellula go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_265488 GO:0061290 biolink:BiologicalProcess canonical Wnt signaling pathway involved in metanephric kidney development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt receptor signaling pathway involved in metanephric kidney development|canonical Wnt receptor signalling pathway involved in metanephric kidney development|canonical Wnt-activated signaling pathway involved in metanephric kidney development http://purl.obolibrary.org/obo/GO_0061290 GO:0061291 biolink:BiologicalProcess canonical Wnt signaling pathway involved in ureteric bud branching The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt receptor signaling pathway involved in ureteric bud branching|canonical Wnt receptor signalling pathway involved in ureteric bud branching http://purl.obolibrary.org/obo/GO_0061291 CHEBI:26253 biolink:ChemicalSubstance polyprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26253 GO:0061292 biolink:BiologicalProcess canonical Wnt signaling pathway involved in mesonephros development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt receptor signaling pathway involved in mesonephros development|canonical Wnt-activated signaling pathway involved in mesonephros development|canonical Wnt receptor signalling pathway involved in mesonephros development http://purl.obolibrary.org/obo/GO_0061292 CHEBI:26254 biolink:ChemicalSubstance prenylnaphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26254 chebi_ph7_3 GO:0061293 biolink:BiologicalProcess canonical Wnt signaling pathway involved in mesonephric nephron development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt-activated signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signalling pathway involved in mesonephric nephron development http://purl.obolibrary.org/obo/GO_0061293 CHEBI:26255 biolink:ChemicalSubstance prenylquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26255 GO:0061294 biolink:BiologicalProcess mesonephric renal vesicle induction Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0061294 GO:0061295 biolink:BiologicalProcess regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. go-plus.json regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061295 GO:0061296 biolink:BiologicalProcess negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. go-plus.json negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061296 CHEBI:26250 biolink:ChemicalSubstance prenol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26250 GO:0061297 biolink:BiologicalProcess positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. go-plus.json positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061297 GO:0061298 biolink:BiologicalProcess retina vasculature development in camera-type eye The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. go-plus.json retinal vasculature development http://purl.obolibrary.org/obo/GO_0061298 GO:0061299 biolink:BiologicalProcess retina vasculature morphogenesis in camera-type eye The process in which the vasculature of the retina is generated and organized. go-plus.json retinal vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0061299 CHEBI:41879 biolink:ChemicalSubstance dexamethasone go-plus.json http://purl.obolibrary.org/obo/CHEBI_41879 chebi_ph7_3 GO:0002940 biolink:BiologicalProcess tRNA N2-guanine methylation The process whereby a guanine in a tRNA is methylated at the N2 position of guanine. go-plus.json tRNA m2-guanine biosynthesis http://purl.obolibrary.org/obo/GO_0002940 CHEBI:26228 biolink:ChemicalSubstance precorrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26228 GO:0002941 biolink:BiologicalProcess synoviocyte proliferation The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0002941 GO:0002942 biolink:BiologicalProcess tRNA m2,2-guanine biosynthesis The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position. go-plus.json http://purl.obolibrary.org/obo/GO_0002942 GO:0002943 biolink:BiologicalProcess tRNA dihydrouridine synthesis The process whereby a uridine in a transfer RNA is converted to dihydrouridine. go-plus.json http://purl.obolibrary.org/obo/GO_0002943 CHEBI:41865 biolink:ChemicalSubstance sebacic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41865 CHEBI:16899 biolink:ChemicalSubstance D-mannitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16899 chebi_ph7_3 CHEBI:16897 biolink:ChemicalSubstance D-erythrose 4-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16897 chebi_ph7_3 GO:0002948 biolink:MolecularActivity archaeosine synthase activity Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA. RHEA:54084|Wikipedia:Archaeosine_synthase|EC:2.6.1.97 go-plus.json ArcS|glutamine:preQ0-tRNA amidinotransferase http://purl.obolibrary.org/obo/GO_0002948 CHEBI:16894 biolink:ChemicalSubstance 3-sulfopyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16894 GO:0002949 biolink:BiologicalProcess tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base). go-plus.json t6A tRNA modification|threonylcarbamoyladenosine biosynthesis|threonylcarbamoyladenosine anabolism|threonylcarbamoyladenosine synthesis|threonylcarbamoyladenosine formation|t6A biosynthesis|t6A biosynthetic process|threonylcarbamoyladenosine biosynthetic process http://purl.obolibrary.org/obo/GO_0002949 CHEBI:16895 biolink:ChemicalSubstance S-methyl-5-thio-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16895 chebi_ph7_3 CHEBI:16892 biolink:ChemicalSubstance 4-amino-5-hydroxymethyl-2-methylpyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16892 chebi_ph7_3 CHEBI:16893 biolink:ChemicalSubstance sphinganine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16893 GO:0002944 biolink:CellularComponent cyclin K-CDK12 complex A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json CycK/Cdk12 complex http://purl.obolibrary.org/obo/GO_0002944 CHEBI:16890 biolink:ChemicalSubstance glycerol monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16890 GO:0002945 biolink:CellularComponent cyclin K-CDK13 complex A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json CycK/Cdk13 complex http://purl.obolibrary.org/obo/GO_0002945 CHEBI:16891 biolink:ChemicalSubstance glyoxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16891 GO:0002946 biolink:BiologicalProcess tRNA C5-cytosine methylation The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine. go-plus.json tRNA 5-methylcytosine biosynthesis http://purl.obolibrary.org/obo/GO_0002946 GO:0002947 biolink:CellularComponent tumor necrosis factor receptor superfamily complex A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily. go-plus.json TNF receptor superfamily complex http://purl.obolibrary.org/obo/GO_0002947 GO:0002951 biolink:MolecularActivity leukotriene-C(4) hydrolase Catalysis of the reaction Leukotriene C(4) + H(2)O= leukotriene D(4) + L-glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0002951 GO:0002952 biolink:MolecularActivity (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione. go-plus.json phospho-AI-2 isomerase activity http://purl.obolibrary.org/obo/GO_0002952 GO:0002953 biolink:MolecularActivity 5'-deoxynucleotidase activity Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0002953 GO:0002950 biolink:MolecularActivity ceramide phosphoethanolamine synthase activity Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine. Reactome:R-HSA-8959462 go-plus.json http://purl.obolibrary.org/obo/GO_0002950 CHEBI:16889 biolink:ChemicalSubstance trans-3-hydroxy-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16889 CHEBI:16887 biolink:ChemicalSubstance 5-(4-hydroxybut-1-ynyl)-2,2'-bithiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16887 chebi_ph7_3 CHEBI:16885 biolink:ChemicalSubstance 1-kestose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16885 chebi_ph7_3 CHEBI:16886 biolink:ChemicalSubstance 2-aminomuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16886 CHEBI:9457 biolink:ChemicalSubstance terpinolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_9457 chebi_ph7_3 CHEBI:16881 biolink:ChemicalSubstance 1H-indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16881 chebi_ph7_3 CHEBI:16880 biolink:ChemicalSubstance L-ribulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16880 chebi_ph7_3 CHEBI:26207 biolink:ChemicalSubstance polyterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26207 CHEBI:26208 biolink:ChemicalSubstance polyunsaturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26208 GO:0002920 biolink:BiologicalProcess regulation of humoral immune response Any process that modulates the frequency, rate, or extent of a humoral immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002920 GO:0002921 biolink:BiologicalProcess negative regulation of humoral immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response. go-plus.json inhibition of humoral immune response|down regulation of humoral immune response|downregulation of humoral immune response|down-regulation of humoral immune response http://purl.obolibrary.org/obo/GO_0002921 CHEBI:26203 biolink:ChemicalSubstance polyprenol triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26203 CHEBI:41847 biolink:ChemicalSubstance 1,2-dioctadecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_41847 chebi_ph7_3 GO:0002926 biolink:BiologicalProcess tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine. go-plus.json tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis|mcm5 modification|mcm5s2U34 biosynthesis http://purl.obolibrary.org/obo/GO_0002926 GO:0002927 biolink:BiologicalProcess archaeosine-tRNA biosynthetic process The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0002927 GO:0002928 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002928 GO:0002929 biolink:CellularComponent MECO complex A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II. go-plus.json meta-coactivator complex http://purl.obolibrary.org/obo/GO_0002929 GO:0002922 biolink:BiologicalProcess positive regulation of humoral immune response Any process that activates or increases the frequency, rate, or extent of a humoral immune response. go-plus.json up-regulation of humoral immune response|upregulation of humoral immune response|up regulation of humoral immune response|activation of humoral immune response|stimulation of humoral immune response http://purl.obolibrary.org/obo/GO_0002922 GO:0002923 biolink:BiologicalProcess regulation of humoral immune response mediated by circulating immunoglobulin Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. go-plus.json http://purl.obolibrary.org/obo/GO_0002923 GO:0002924 biolink:BiologicalProcess negative regulation of humoral immune response mediated by circulating immunoglobulin Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. go-plus.json down-regulation of humoral immune response mediated by circulating immunoglobulin|downregulation of humoral immune response mediated by circulating immunoglobulin|down regulation of humoral immune response mediated by circulating immunoglobulin|inhibition of humoral immune response mediated by circulating immunoglobulin http://purl.obolibrary.org/obo/GO_0002924 GO:0002925 biolink:BiologicalProcess positive regulation of humoral immune response mediated by circulating immunoglobulin Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. go-plus.json up regulation of humoral immune response mediated by circulating immunoglobulin|upregulation of humoral immune response mediated by circulating immunoglobulin|stimulation of humoral immune response mediated by circulating immunoglobulin|up-regulation of humoral immune response mediated by circulating immunoglobulin|activation of humoral immune response mediated by circulating immunoglobulin http://purl.obolibrary.org/obo/GO_0002925 CHEBI:26217 biolink:ChemicalSubstance potassium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_26217 GO:0002930 biolink:BiologicalProcess trabecular meshwork development The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. go-plus.json http://purl.obolibrary.org/obo/GO_0002930 GO:0002931 biolink:BiologicalProcess response to ischemia Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply. go-plus.json http://purl.obolibrary.org/obo/GO_0002931 GO:0002932 biolink:BiologicalProcess tendon sheath development The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. go-plus.json http://purl.obolibrary.org/obo/GO_0002932 CHEBI:9440 biolink:ChemicalSubstance tenuazonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9440 CHEBI:26214 biolink:ChemicalSubstance porphyrins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26214 CHEBI:26216 biolink:ChemicalSubstance potassium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_26216 chebi_ph7_3 CHEBI:41837 biolink:ChemicalSubstance (4S,5S)-1,2-dithiane-4,5-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_41837 chebi_ph7_3 GO:0002937 biolink:BiologicalProcess tRNA 4-thiouridine biosynthesis The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0002937 GO:0002938 biolink:BiologicalProcess tRNA guanine ribose methylation The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0002938 GO:0002939 biolink:BiologicalProcess tRNA N1-guanine methylation The process whereby a guanine in tRNA is methylated at position N1 of the guanine. go-plus.json tRNA m1-guanine biosynthesis http://purl.obolibrary.org/obo/GO_0002939 GO:0002933 biolink:BiologicalProcess lipid hydroxylation The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid. go-plus.json fatty acid hydroxylation http://purl.obolibrary.org/obo/GO_0002933 GO:0002934 biolink:BiologicalProcess desmosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0002934 GO:0002935 biolink:MolecularActivity tRNA (adenine-C2-)-methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0002935 GO:0002936 biolink:BiologicalProcess bradykinin biosynthetic process The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin. go-plus.json http://purl.obolibrary.org/obo/GO_0002936 GO:0051874 biolink:BiologicalProcess sphinganine-1-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. go-plus.json dihydrosphingosine-1-phosphate catabolic process|dihydrosphingosine-1-phosphate catabolism http://purl.obolibrary.org/obo/GO_0051874 GO:0051875 biolink:BiologicalProcess pigment granule localization Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. go-plus.json pigment granule localisation http://purl.obolibrary.org/obo/GO_0051875 CHEBI:9493 biolink:ChemicalSubstance tetrahymanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_9493 chebi_ph7_3 GO:0051872 biolink:BiologicalProcess sphingosine catabolic process The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. go-plus.json (4E)-sphing-4-enine catabolism|sphing-4-enine catabolism|sphing-4-enine catabolic process|(4E)-sphing-4-enine catabolic process http://purl.obolibrary.org/obo/GO_0051872 CHEBI:145565 biolink:ChemicalSubstance macrolide lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_145565 GO:0051873 biolink:BiologicalProcess killing by host of symbiont cells Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json disruption by host of symbiont cells http://purl.obolibrary.org/obo/GO_0051873 CHEBI:90790 biolink:ChemicalSubstance 18(R)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90790 chebi_ph7_3 GO:0051878 biolink:BiologicalProcess lateral element assembly The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements. go-plus.json http://purl.obolibrary.org/obo/GO_0051878 GO:0051879 biolink:MolecularActivity Hsp90 protein binding Binding to Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size. go-plus.json Hsp90 class protein binding|Hsp90 binding http://purl.obolibrary.org/obo/GO_0051879 GO:0051876 biolink:BiologicalProcess pigment granule dispersal The directed movement of pigment granules within a cell towards the cell periphery. go-plus.json http://purl.obolibrary.org/obo/GO_0051876 GO:0051877 biolink:BiologicalProcess pigment granule aggregation in cell center The directed movement of dispersed pigment granules towards the center of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051877 GO:0061200 biolink:CellularComponent clathrin-sculpted gamma-aminobutyric acid transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle. go-plus.json clathrin sculpted gamma-aminobutyric acid transport vesicle|clathrin sculpted GABA transport vesicle http://purl.obolibrary.org/obo/GO_0061200 GO:0036233 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036233 GO:0061201 biolink:CellularComponent clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle. go-plus.json clathrin sculpted GABA transport vesicle lumen|clathrin sculpted gamma-aminobutyric acid transport vesicle lumen http://purl.obolibrary.org/obo/GO_0061201 GO:0036234 biolink:BiologicalProcess deglucuronidation The removal of glucuronic acid from a conjugated substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0036234 GO:0036235 biolink:BiologicalProcess acyl deglucuronidation The removal of glucuronic acid from an acyl-glucuronide. go-plus.json http://purl.obolibrary.org/obo/GO_0036235 GO:0061202 biolink:CellularComponent clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle. go-plus.json clathrin sculpted GABA transport vesicle membrane|clathrin sculpted gamma-aminobutyric acid transport vesicle membrane http://purl.obolibrary.org/obo/GO_0061202 GO:0036236 biolink:BiologicalProcess acyl glucuronidation The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside). go-plus.json http://purl.obolibrary.org/obo/GO_0036236 GO:0061203 biolink:BiologicalProcess striated muscle paramyosin thick filament assembly The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0061203 CHEBI:90799 biolink:ChemicalSubstance dipeptide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_90799 chebi_ph7_3 GO:0036237 biolink:MolecularActivity acyl-glucuronidase activity Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate. go-plus.json acyl-glucuronide deglucuronidation activity http://purl.obolibrary.org/obo/GO_0036237 GO:0061204 biolink:BiologicalProcess paramyosin filament assembly or disassembly The formation or disassembly of a filament composed of paramyosin molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0061204 CHEBI:75150 biolink:ChemicalSubstance 3-dehydro-D-glucose-6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75150 GO:0036238 biolink:MolecularActivity gallate dioxygenase activity Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate. KEGG_REACTION:R09565|MetaCyc:GALLATE-DIOXYGENASE-RXN|EC:1.13.11.57|RHEA:28927 go-plus.json http://purl.obolibrary.org/obo/GO_0036238 GO:0061205 biolink:BiologicalProcess paramesonephric duct development The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. go-plus.json Mullerian duct development http://purl.obolibrary.org/obo/GO_0061205 GO:0061206 biolink:BiologicalProcess mesonephros morphogenesis The process in which the anatomical structures of the mesonephros are generated and organized. go-plus.json Wolffian body morphogenesis http://purl.obolibrary.org/obo/GO_0061206 GO:0036239 biolink:MolecularActivity taxoid 7beta-hydroxylase activity Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O. MetaCyc:RXN-12885|EC:1.14.13.147|RHEA:31975|KEGG_REACTION:R09868 go-plus.json http://purl.obolibrary.org/obo/GO_0036239 GO:0061207 biolink:BiologicalProcess mesonephric juxtaglomerulus cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061207 CHEBI:90795 biolink:ChemicalSubstance bacteriochlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90795 chebi_ph7_3 GO:0061208 biolink:BiologicalProcess cell differentiation involved in mesonephros development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061208 GO:0061209 biolink:BiologicalProcess cell proliferation involved in mesonephros development The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061209 CHEBI:75155 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75155 chebi_ph7_3 CHEBI:90796 biolink:ChemicalSubstance D-erythrulose 4-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90796 chebi_ph7_3 CHEBI:90797 biolink:ChemicalSubstance 19-hydroxyprostaglandin H2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90797 chebi_ph7_3 CHEBI:90798 biolink:ChemicalSubstance L-erythrulose 4-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90798 chebi_ph7_3 CHEBI:75158 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75158 chebi_ph7_3 GO:0051870 biolink:MolecularActivity methotrexate binding Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0051870 CHEBI:90791 biolink:ChemicalSubstance 3-(1-hydroxyethyl)bacteriochlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90791 chebi_ph7_3 GO:0051871 biolink:MolecularActivity dihydrofolic acid binding Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms. go-plus.json dihydrofolate binding|DHF binding http://purl.obolibrary.org/obo/GO_0051871 GO:0036230 biolink:BiologicalProcess granulocyte activation The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0036230 CHEBI:90792 biolink:ChemicalSubstance 3-(1-hydroxyethyl)chlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90792 chebi_ph7_3 CHEBI:90793 biolink:ChemicalSubstance prostaglandin H1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90793 chebi_ph7_3 GO:0036231 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036231 CHEBI:90794 biolink:ChemicalSubstance 3-acetylchlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90794 chebi_ph7_3 GO:0036232 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036232 GO:0051885 biolink:BiologicalProcess positive regulation of timing of anagen Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. go-plus.json upregulation of anagen|stimulation of anagen|activation of anagen|up-regulation of anagen|positive regulation of anagen|up regulation of anagen http://purl.obolibrary.org/obo/GO_0051885 GO:0051886 biolink:BiologicalProcess negative regulation of timing of anagen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. go-plus.json downregulation of anagen|inhibition of anagen|down regulation of anagen|negative regulation of anagen|down-regulation of anagen http://purl.obolibrary.org/obo/GO_0051886 GO:0051883 biolink:BiologicalProcess killing of cells in other organism involved in symbiotic interaction Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json killing of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051883 GO:0051884 biolink:BiologicalProcess regulation of timing of anagen Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. go-plus.json regulation of anagen http://purl.obolibrary.org/obo/GO_0051884 CHEBI:145555 biolink:ChemicalSubstance macropolylide go-plus.json http://purl.obolibrary.org/obo/CHEBI_145555 GO:0051889 biolink:BiologicalProcess negative regulation of timing of exogen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. go-plus.json down-regulation of exogen|negative regulation of exogen|downregulation of exogen|inhibition of exogen|down regulation of exogen http://purl.obolibrary.org/obo/GO_0051889 CHEBI:145556 biolink:ChemicalSubstance macrodiolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_145556 GO:0051887 biolink:BiologicalProcess regulation of timing of exogen Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. go-plus.json regulation of exogen http://purl.obolibrary.org/obo/GO_0051887 GO:0051888 biolink:BiologicalProcess positive regulation of timing of exogen Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. go-plus.json positive regulation of exogen|up regulation of exogen|upregulation of exogen|stimulation of exogen|activation of exogen|up-regulation of exogen http://purl.obolibrary.org/obo/GO_0051888 CHEBI:145559 biolink:ChemicalSubstance macrotriolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_145559 CHEBI:145550 biolink:ChemicalSubstance peregrinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_145550 chebi_ph7_3 GO:0036222 biolink:MolecularActivity XTP diphosphatase activity Catalysis of the reaction: XTP + H2O <=> H+ + XDP + monophosphate. KEGG_REACTION:R02720|EC:3.6.1.66|MetaCyc:RXN0-5074|RHEA:28610|MetaCyc:RXN0-1603|Reactome:R-HSA-2509831 go-plus.json XTPase activity|hypoxanthine/xanthine dNTP pyrophosphatase|XTP pyrophosphohydrolase activity|XTP/dITP diphosphatase http://purl.obolibrary.org/obo/GO_0036222 GO:0036223 biolink:BiologicalProcess cellular response to adenine starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine. go-plus.json cellular response to adenine deprivation http://purl.obolibrary.org/obo/GO_0036223 GO:0036224 biolink:CellularComponent pairing center A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment. go-plus.json homolog recognition region http://purl.obolibrary.org/obo/GO_0036224 GO:0036225 biolink:BiologicalProcess cellular response to vitamin B1 starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine). go-plus.json cellular response to vitamin B1 deprivation|cellular response to thiamin starvation http://purl.obolibrary.org/obo/GO_0036225 CHEBI:75161 biolink:ChemicalSubstance 1-myristoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75161 chebi_ph7_3 GO:0036226 biolink:BiologicalProcess obsolete mitotic cell cycle arrest in response to glucose starvation OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose. go-plus.json cell cycle arrest in response to glucose starvation http://purl.obolibrary.org/obo/GO_0036226 GO:0036227 biolink:BiologicalProcess mitotic G2 cell cycle arrest in response to glucose starvation The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0036227 GO:0036228 biolink:BiologicalProcess protein localization to nuclear inner membrane A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane. go-plus.json protein targeting to nuclear inner membrane|protein targeting to INM http://purl.obolibrary.org/obo/GO_0036228 CHEBI:75160 biolink:ChemicalSubstance 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75160 chebi_ph7_3 GO:0036229 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036229 CHEBI:90784 biolink:ChemicalSubstance aurachin B(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90784 chebi_ph7_3 CHEBI:90785 biolink:ChemicalSubstance 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_90785 chebi_ph7_3 CHEBI:51177 biolink:ChemicalSubstance antitussive go-plus.json http://purl.obolibrary.org/obo/CHEBI_51177 CHEBI:90786 biolink:ChemicalSubstance 2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90786 chebi_ph7_3 CHEBI:75163 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75163 chebi_ph7_3 CHEBI:75169 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75169 GO:0051881 biolink:BiologicalProcess regulation of mitochondrial membrane potential Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0051881 GO:0051882 biolink:BiologicalProcess mitochondrial depolarization The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. go-plus.json mitochondrion depolarization|mitochondria depolarization|mitochondrial depolarisation|mitochondrial membrane depolarization http://purl.obolibrary.org/obo/GO_0051882 CHEBI:90781 biolink:ChemicalSubstance 13-oxo-9Z,11E-ODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90781 chebi_ph7_3 GO:0036220 biolink:MolecularActivity ITP diphosphatase activity Catalysis of the reaction: ITP + H2O = IMP + diphosphate. KEGG_REACTION:R00720|MetaCyc:RXN0-6382|RHEA:29399|Reactome:R-HSA-2509827 go-plus.json inosine-5'-triphosphate pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0036220 CHEBI:90782 biolink:ChemicalSubstance C-terminal proteinogenic amino-acid residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90782 chebi_ph7_3 CHEBI:90783 biolink:ChemicalSubstance C-terminal S-(Gly-Gly)-L-Cys zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90783 chebi_ph7_3 GO:0036221 biolink:MolecularActivity UTP diphosphatase activity Catalysis of the reaction: UTP + H2O = UMP + diphosphate. KEGG_REACTION:R00662|RHEA:29395 go-plus.json uridine triphosphate pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0036221 GO:0051880 biolink:MolecularActivity G-quadruplex DNA binding Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. go-plus.json G-quartet DNA binding|G-quartet binding|tetraplex DNA binding|G-DNA binding|quadruplex DNA binding|G quartet DNA binding|G quadruplex DNA binding|G quartet binding http://purl.obolibrary.org/obo/GO_0051880 CHEBI:75168 biolink:ChemicalSubstance 1-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75168 GO:0051896 biolink:BiologicalProcess regulation of protein kinase B signaling Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. go-plus.json regulation of PKB signalling cascade|regulation of protein kinase B signalling cascade|regulation of AKT signalling cascade|regulation of protein kinase B signaling cascade|regulation of AKT signaling cascade|regulation of PKB signaling cascade http://purl.obolibrary.org/obo/GO_0051896 CHEBI:9470 biolink:ChemicalSubstance tetracenomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_9470 chebi_ph7_3 GO:0051897 biolink:BiologicalProcess positive regulation of protein kinase B signaling Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. go-plus.json positive regulation of PKB signaling cascade|upregulation of protein kinase B signaling cascade|positive regulation of AKT signaling cascade|stimulation of protein kinase B signaling cascade|activation of protein kinase B signaling cascade|positive regulation of protein kinase B signalling cascade|up-regulation of protein kinase B signaling cascade|up regulation of protein kinase B signaling cascade|positive regulation of AKT signalling cascade|positive regulation of PKB signalling cascade|positive regulation of protein kinase B signaling cascade http://purl.obolibrary.org/obo/GO_0051897 GO:0051894 biolink:BiologicalProcess positive regulation of focal adhesion assembly Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. go-plus.json up regulation of focal adhesion formation|upregulation of focal adhesion formation|stimulation of focal adhesion formation|up-regulation of focal adhesion formation|activation of focal adhesion formation http://purl.obolibrary.org/obo/GO_0051894 GO:0051895 biolink:BiologicalProcess negative regulation of focal adhesion assembly Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. go-plus.json downregulation of focal adhesion formation|down regulation of focal adhesion formation|inhibition of focal adhesion formation|down-regulation of focal adhesion formation http://purl.obolibrary.org/obo/GO_0051895 CHEBI:145544 biolink:ChemicalSubstance S-nitrosoglutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145544 chebi_ph7_3 CHEBI:145545 biolink:ChemicalSubstance nitrosothio compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_145545 chebi_ph7_3 GO:0051898 biolink:BiologicalProcess negative regulation of protein kinase B signaling Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. go-plus.json negative regulation of PKB signaling cascade|negative regulation of AKT signaling cascade|negative regulation of protein kinase B signalling cascade|down-regulation of protein kinase B signaling cascade|negative regulation of AKT signalling cascade|negative regulation of PKB signalling cascade|negative regulation of protein kinase B signaling cascade|downregulation of protein kinase B signaling cascade|inhibition of protein kinase B signaling cascade|down regulation of protein kinase B signaling cascade http://purl.obolibrary.org/obo/GO_0051898 GO:0051899 biolink:BiologicalProcess membrane depolarization The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json http://purl.obolibrary.org/obo/GO_0051899 GO:0036219 biolink:MolecularActivity GTP diphosphatase activity Catalysis of the reaction: GTP + H2O = GMP + diphosphate. RHEA:29391|KEGG_REACTION:R00426 go-plus.json GTP diphosphohydrolase activity|GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase http://purl.obolibrary.org/obo/GO_0036219 GO:0061220 biolink:BiologicalProcess mesonephric macula densa development The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061220 GO:0061221 biolink:BiologicalProcess mesonephric mesenchyme morphogenesis The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061221 GO:0036211 biolink:BiologicalProcess protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). go-plus.json protein modification http://purl.obolibrary.org/obo/GO_0036211 GO:0061222 biolink:BiologicalProcess mesonephric mesenchymal cell proliferation involved in mesonephros development The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0061222 GO:0061223 biolink:BiologicalProcess mesonephric mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061223 GO:0036212 biolink:BiologicalProcess contractile ring maintenance The process in which the contractile ring is maintained, typically in response to an internal or external cue. go-plus.json http://purl.obolibrary.org/obo/GO_0036212 GO:0061224 biolink:BiologicalProcess mesonephric glomerulus development The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061224 GO:0036213 biolink:BiologicalProcess contractile ring contraction The process of an actomyosin ring getting smaller in diameter. go-plus.json contractile ring constriction http://purl.obolibrary.org/obo/GO_0036213 GO:0061225 biolink:BiologicalProcess mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. go-plus.json mesonephric Goormaghtigh proliferation|mesonephric lacis cell proliferation http://purl.obolibrary.org/obo/GO_0061225 GO:0036214 biolink:BiologicalProcess contractile ring localization The process in which a contractile ring is assembled and/or maintained in a specific location. go-plus.json http://purl.obolibrary.org/obo/GO_0036214 GO:0036215 biolink:BiologicalProcess response to stem cell factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus. go-plus.json response to stem cell factor stimulus|response to KIT ligand|response to hematopoietic growth factor KL|response to SCF http://purl.obolibrary.org/obo/GO_0036215 GO:0061226 biolink:BiologicalProcess proximal/distal pattern formation involved in mesonephric nephron development The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end). go-plus.json http://purl.obolibrary.org/obo/GO_0061226 CHEBI:75173 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75173 chebi_ph7_3 GO:0036216 biolink:BiologicalProcess cellular response to stem cell factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus. go-plus.json cellular response to KITLG|cellular response to SCF|cellular response to KIT ligand|cellular response to hematopoietic growth factor KL http://purl.obolibrary.org/obo/GO_0036216 GO:0061227 biolink:BiologicalProcess pattern specification involved in mesonephros development Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate. go-plus.json mesonephros pattern formation|mesonephros pattern specification http://purl.obolibrary.org/obo/GO_0061227 GO:0036217 biolink:MolecularActivity dGTP diphosphatase activity Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate. RHEA:28362|KEGG_REACTION:R01855 go-plus.json 2'-deoxyguanosine 5'-triphosphate diphosphohydrolase http://purl.obolibrary.org/obo/GO_0036217 GO:0061228 biolink:BiologicalProcess mesonephric nephron morphogenesis The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061228 GO:0036218 biolink:MolecularActivity dTTP diphosphatase activity Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate. RHEA:28534|MetaCyc:RXN0-5107|EC:3.6.1.9 go-plus.json http://purl.obolibrary.org/obo/GO_0036218 GO:0061229 biolink:BiologicalProcess mesonephric juxtaglomerulus cell development The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061229 GO:0051892 biolink:BiologicalProcess negative regulation of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json down regulation of cardioblast differentiation|downregulation of cardioblast differentiation|down-regulation of cardioblast differentiation|inhibition of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051892 GO:0051893 biolink:BiologicalProcess regulation of focal adhesion assembly Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions. go-plus.json regulation of adhesion plaque assembly http://purl.obolibrary.org/obo/GO_0051893 GO:0051890 biolink:BiologicalProcess regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0051890 GO:0051891 biolink:BiologicalProcess positive regulation of cardioblast differentiation Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json up regulation of cardioblast differentiation|activation of cardioblast differentiation|stimulation of cardioblast differentiation|up-regulation of cardioblast differentiation|upregulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051891 GO:0036210 biolink:BiologicalProcess protein modification process in other organism The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). go-plus.json protein modification in other organism http://purl.obolibrary.org/obo/GO_0036210 GO:0036208 biolink:BiologicalProcess obsolete negative regulation of histone gene expression OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. go-plus.json down-regulation of histone gene expression|inhibition of histone gene expression|negative regulation of expression of histone-encoding gene|downregulation of histone gene expression http://purl.obolibrary.org/obo/GO_0036208 GO:0036209 biolink:MolecularActivity 9beta-pimara-7,15-diene oxidase activity Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase]. EC:1.14.14.111|RHEA:31951|KEGG_REACTION:R09865|MetaCyc:RXN-15437 go-plus.json 9-beta-stemod-13(17)-ene oxidase activity http://purl.obolibrary.org/obo/GO_0036209 GO:0061210 biolink:BiologicalProcess cell-cell signaling involved in mesonephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ. go-plus.json cell-cell signalling involved in mesonephros development http://purl.obolibrary.org/obo/GO_0061210 GO:0061211 biolink:BiologicalProcess mesonephric collecting duct development The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0061211 GO:0036200 biolink:MolecularActivity 3-ketosteroid 9-alpha-monooxygenase activity Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O. EC:1.14.15.30|RHEA:32199|KEGG_REACTION:R09860 go-plus.json KshAB activity|3-ketosteroid 9alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0036200 GO:0036201 biolink:MolecularActivity ent-isokaurene C2-hydroxylase activity Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+. RHEA:56336|KEGG_REACTION:R09861|EC:1.14.14.76 go-plus.json http://purl.obolibrary.org/obo/GO_0036201 GO:0061212 biolink:BiologicalProcess mesonephric juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. go-plus.json http://purl.obolibrary.org/obo/GO_0061212 GO:0036202 biolink:MolecularActivity ent-cassa-12,15-diene 11-hydroxylase activity Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O. RHEA:31967|KEGG_REACTION:R09866|EC:1.14.14.112 go-plus.json ent-cassadiene C11alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0036202 GO:0061213 biolink:BiologicalProcess positive regulation of mesonephros development Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0061213 GO:0061214 biolink:BiologicalProcess mesonephric smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061214 GO:0036203 biolink:MolecularActivity taxoid 14-beta-hydroxylase activity Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O. RHEA:31971|KEGG_REACTION:R09867|EC:1.14.13.146 go-plus.json http://purl.obolibrary.org/obo/GO_0036203 GO:0036204 biolink:MolecularActivity abieta-7,13-dien-18-ol hydroxylase activity Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O. EC:1.14.14.145|KEGG_REACTION:R06354|RHEA:26221|MetaCyc:RXN-12799 go-plus.json http://purl.obolibrary.org/obo/GO_0036204 GO:0061215 biolink:BiologicalProcess mesonephric nephron development The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0061215 GO:0061216 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in mesonephros development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061216 GO:0036205 biolink:BiologicalProcess histone catabolic process The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells. go-plus.json histone protein catabolic process http://purl.obolibrary.org/obo/GO_0036205 GO:0061217 biolink:BiologicalProcess regulation of mesonephros development Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0061217 GO:0036206 biolink:BiologicalProcess obsolete regulation of histone gene expression OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. go-plus.json regulation of expression of histone-encoding gene http://purl.obolibrary.org/obo/GO_0036206 GO:0061218 biolink:BiologicalProcess negative regulation of mesonephros development Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0061218 GO:0036207 biolink:BiologicalProcess obsolete positive regulation of histone gene expression OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. go-plus.json up-regulation of histone gene expression|positive regulation of expression of histone-encoding gene|upregulation of histone gene expression|activation of histone gene expression http://purl.obolibrary.org/obo/GO_0036207 GO:0061219 biolink:BiologicalProcess mesonephric mesenchyme development The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061219 CHEBI:145538 biolink:ChemicalSubstance N-acylethanolamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_145538 CHEBI:566274 biolink:ChemicalSubstance malonaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_566274 chebi_ph7_3 CHEBI:51151 biolink:ChemicalSubstance dipolar compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_51151 CHEBI:75189 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_75189 chebi_ph7_3 CHEBI:51149 biolink:ChemicalSubstance xanthones go-plus.json http://purl.obolibrary.org/obo/CHEBI_51149 CHEBI:26187 biolink:ChemicalSubstance polyprenyl phospho carbohydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26187 CHEBI:26188 biolink:ChemicalSubstance polyketide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26188 GO:0061240 biolink:BiologicalProcess mesonephric nephron tubule morphogenesis The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061240 GO:0061241 biolink:BiologicalProcess mesonephric nephron epithelium development The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061241 GO:0061242 biolink:BiologicalProcess mesonephric nephron tubule development The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061242 CHEBI:26185 biolink:ChemicalSubstance polyprenyl glycosyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26185 GO:0061243 biolink:BiologicalProcess mesonephric renal vesicle morphogenesis The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061243 CHEBI:26186 biolink:ChemicalSubstance polyprenyl phospho oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26186 GO:0061244 biolink:BiologicalProcess mesonephric S-shaped body morphogenesis The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061244 CHEBI:75190 biolink:ChemicalSubstance EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75190 GO:0061245 biolink:BiologicalProcess establishment or maintenance of bipolar cell polarity Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns. go-plus.json http://purl.obolibrary.org/obo/GO_0061245 CHEBI:26191 biolink:ChemicalSubstance polyol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26191 CHEBI:75191 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phosphonato-alpha-D-mannosyl group(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75191 chebi_ph7_3 GO:0061246 biolink:BiologicalProcess establishment or maintenance of bipolar cell polarity regulating cell shape Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061246 GO:0061247 biolink:BiologicalProcess mesonephric glomerular mesangium development The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061247 GO:0061248 biolink:BiologicalProcess mesonephric glomerulus vasculature morphogenesis The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061248 CHEBI:75194 biolink:ChemicalSubstance phosphatidylinositol 36:4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75194 chebi_ph7_3 GO:0061249 biolink:BiologicalProcess mesonephric glomerular capillary formation The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0061249 CHEBI:75195 biolink:ChemicalSubstance phosphatidylglycerol 32:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75195 chebi_ph7_3 CHEBI:51143 biolink:ChemicalSubstance nitrogen molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_51143 CHEBI:75199 biolink:ChemicalSubstance phosphatidylglycerol 36:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75199 chebi_ph7_3 CHEBI:51144 biolink:ChemicalSubstance nitrogen group go-plus.json http://purl.obolibrary.org/obo/CHEBI_51144 CHEBI:51145 biolink:ChemicalSubstance secondary amino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_51145 CHEBI:75196 biolink:ChemicalSubstance phosphatidylglycerol 32:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75196 chebi_ph7_3 CHEBI:51142 biolink:ChemicalSubstance amino groups go-plus.json http://purl.obolibrary.org/obo/CHEBI_51142 NCBITaxon:241407 biolink:OrganismalEntity Saccharomycetales incertae sedis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_241407 CHEBI:26199 biolink:ChemicalSubstance polyprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26199 chebi_ph7_3 GO:0061230 biolink:BiologicalProcess mesonephric juxtaglomerulus cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061230 CHEBI:26195 biolink:ChemicalSubstance polyphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26195 GO:0061231 biolink:BiologicalProcess mesonephric glomerulus vasculature development The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061231 CHEBI:26196 biolink:ChemicalSubstance polyphenylpropanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26196 GO:0061232 biolink:BiologicalProcess mesonephric glomerular epithelium development The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061232 GO:0061233 biolink:BiologicalProcess mesonephric glomerular basement membrane development The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration. go-plus.json http://purl.obolibrary.org/obo/GO_0061233 GO:0061234 biolink:BiologicalProcess mesonephric glomerulus morphogenesis The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061234 GO:0061235 biolink:BiologicalProcess mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061235 GO:0061236 biolink:BiologicalProcess mesonephric comma-shaped body morphogenesis The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061236 GO:0061237 biolink:BiologicalProcess convergent extension involved in mesonephric nephron morphogenesis The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061237 GO:0061238 biolink:BiologicalProcess establishment of planar polarity involved in mesonephric nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros. go-plus.json establishment of planar cell polarity involved in mesonephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0061238 GO:0061239 biolink:BiologicalProcess mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061239 CHEBI:51132 biolink:ChemicalSubstance nitroarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51132 GO:0002885 biolink:BiologicalProcess positive regulation of hypersensitivity Any process that activates or increases the frequency, rate, or extent of hypersensitivity. go-plus.json up regulation of hypersensitivity|upregulation of hypersensitivity|stimulation of hypersensitivity|up-regulation of hypersensitivity|activation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002885 CHEBI:51129 biolink:ChemicalSubstance nitrohydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_51129 GO:0002886 biolink:BiologicalProcess regulation of myeloid leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. go-plus.json http://purl.obolibrary.org/obo/GO_0002886 GO:0002887 biolink:BiologicalProcess negative regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. go-plus.json down regulation of myeloid leukocyte mediated immunity|downregulation of myeloid leukocyte mediated immunity|down-regulation of myeloid leukocyte mediated immunity|inhibition of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002887 GO:0002888 biolink:BiologicalProcess positive regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. go-plus.json upregulation of myeloid leukocyte mediated immunity|up regulation of myeloid leukocyte mediated immunity|activation of myeloid leukocyte mediated immunity|stimulation of myeloid leukocyte mediated immunity|up-regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002888 GO:0002881 biolink:BiologicalProcess negative regulation of chronic inflammatory response to non-antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. go-plus.json down regulation of chronic inflammatory response to non-antigenic stimulus|downregulation of chronic inflammatory response to non-antigenic stimulus|down-regulation of chronic inflammatory response to non-antigenic stimulus|inhibition of chronic inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002881 GO:0002882 biolink:BiologicalProcess positive regulation of chronic inflammatory response to non-antigenic stimulus Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. go-plus.json upregulation of chronic inflammatory response to non-antigenic stimulus|up regulation of chronic inflammatory response to non-antigenic stimulus|activation of chronic inflammatory response to non-antigenic stimulus|stimulation of chronic inflammatory response to non-antigenic stimulus|up-regulation of chronic inflammatory response to non-antigenic stimulus http://purl.obolibrary.org/obo/GO_0002882 GO:0002883 biolink:BiologicalProcess regulation of hypersensitivity Any process that modulates the frequency, rate, or extent of hypersensitivity. go-plus.json http://purl.obolibrary.org/obo/GO_0002883 GO:0002884 biolink:BiologicalProcess negative regulation of hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity. go-plus.json downregulation of hypersensitivity|down regulation of hypersensitivity|inhibition of hypersensitivity|down-regulation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002884 GO:0061260 biolink:BiologicalProcess mesonephric mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061260 CHEBI:26167 biolink:ChemicalSubstance polar amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26167 GO:0061261 biolink:BiologicalProcess mesenchymal to epithelial transition involved in mesonephros morphogenesis A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros. go-plus.json mesonephric mesenchyme to epithelial transition http://purl.obolibrary.org/obo/GO_0061261 GO:0002880 biolink:BiologicalProcess regulation of chronic inflammatory response to non-antigenic stimulus Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002880 GO:0061262 biolink:BiologicalProcess mesonephric renal vesicle formation The developmental process pertaining to the initial formation of the mesonephros. go-plus.json mesonephros formation http://purl.obolibrary.org/obo/GO_0061262 GO:0061263 biolink:BiologicalProcess mesonephric glomerular mesangial cell development The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061263 GO:0061264 biolink:BiologicalProcess mesonephric glomerular mesangial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061264 GO:0061265 biolink:BiologicalProcess mesonephric nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061265 GO:0061266 biolink:BiologicalProcess mesonephric interstitial fibroblast differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state. go-plus.json mesonephros interstitial cell differentiation http://purl.obolibrary.org/obo/GO_0061266 GO:0061267 biolink:BiologicalProcess mesonephric interstitial fibroblast development The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure. go-plus.json mesonephros interstitial cell development http://purl.obolibrary.org/obo/GO_0061267 GO:0061268 biolink:BiologicalProcess mesonephric interstitial fibroblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast. go-plus.json http://purl.obolibrary.org/obo/GO_0061268 GO:0061269 biolink:BiologicalProcess mesonephric glomerular mesangial cell proliferation involved in mesonephros development The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population. go-plus.json http://purl.obolibrary.org/obo/GO_0061269 CHEBI:51121 biolink:ChemicalSubstance fluorescent dye go-plus.json http://purl.obolibrary.org/obo/CHEBI_51121 GO:0002889 biolink:BiologicalProcess regulation of immunoglobulin mediated immune response Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002889 CHEBI:51120 biolink:ChemicalSubstance ortho- and peri-fused tricyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_51120 GO:0002896 biolink:BiologicalProcess negative regulation of central B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction. go-plus.json down-regulation of central B cell tolerance induction|downregulation of central B cell tolerance induction|down regulation of central B cell tolerance induction|inhibition of central B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002896 GO:0002897 biolink:BiologicalProcess positive regulation of central B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction. go-plus.json up regulation of central B cell tolerance induction|upregulation of central B cell tolerance induction|stimulation of central B cell tolerance induction|up-regulation of central B cell tolerance induction|activation of central B cell tolerance induction http://purl.obolibrary.org/obo/GO_0002897 CHEBI:51119 biolink:ChemicalSubstance tricyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_51119 GO:0002898 biolink:BiologicalProcess regulation of central B cell deletion Any process that modulates the frequency, rate, or extent of central B cell deletion. go-plus.json http://purl.obolibrary.org/obo/GO_0002898 GO:0002899 biolink:BiologicalProcess negative regulation of central B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion. go-plus.json down regulation of central B cell deletion|downregulation of central B cell deletion|down-regulation of central B cell deletion|inhibition of central B cell deletion http://purl.obolibrary.org/obo/GO_0002899 GO:0002892 biolink:BiologicalProcess regulation of type II hypersensitivity Any process that modulates the frequency, rate, or extent of type II hypersensitivity. go-plus.json http://purl.obolibrary.org/obo/GO_0002892 GO:0002893 biolink:BiologicalProcess negative regulation of type II hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity. go-plus.json down-regulation of type II hypersensitivity|downregulation of type II hypersensitivity|down regulation of type II hypersensitivity|inhibition of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002893 GO:0002894 biolink:BiologicalProcess positive regulation of type II hypersensitivity Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity. go-plus.json stimulation of type II hypersensitivity|activation of type II hypersensitivity|up-regulation of type II hypersensitivity|up regulation of type II hypersensitivity|upregulation of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002894 GO:0002895 biolink:BiologicalProcess regulation of central B cell tolerance induction Any process that modulates the frequency, rate, or extent of central B cell tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0002895 CHEBI:26177 biolink:ChemicalSubstance polyene antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_26177 GO:0002890 biolink:BiologicalProcess negative regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response. go-plus.json downregulation of immunoglobulin mediated immune response|down-regulation of immunoglobulin mediated immune response|inhibition of immunoglobulin mediated immune response|down regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002890 CHEBI:26178 biolink:ChemicalSubstance polyester macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_26178 GO:0002891 biolink:BiologicalProcess positive regulation of immunoglobulin mediated immune response Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. go-plus.json up regulation of immunoglobulin mediated immune response|activation of immunoglobulin mediated immune response|stimulation of immunoglobulin mediated immune response|up-regulation of immunoglobulin mediated immune response|upregulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002891 GO:0061250 biolink:BiologicalProcess mesonephric glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061250 CHEBI:26179 biolink:ChemicalSubstance polyether antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_26179 GO:0061251 biolink:BiologicalProcess mesonephric glomerular epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061251 CHEBI:26172 biolink:ChemicalSubstance poly(ribitol phosphate)s go-plus.json http://purl.obolibrary.org/obo/CHEBI_26172 GO:0061252 biolink:BiologicalProcess mesonephric glomerular epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061252 CHEBI:26174 biolink:ChemicalSubstance poly(N-acetyllactosamine) go-plus.json http://purl.obolibrary.org/obo/CHEBI_26174 chebi_ph7_3 GO:0061253 biolink:BiologicalProcess mesonephric glomerular parietal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0061253 GO:0061254 biolink:BiologicalProcess mesonephric glomerular parietal epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0061254 GO:0061255 biolink:BiologicalProcess mesonephric glomerular parietal epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0061255 GO:0061256 biolink:BiologicalProcess mesonephric glomerular visceral epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061256 GO:0061257 biolink:BiologicalProcess mesonephric glomerular visceral epithelial cell development The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061257 GO:0061258 biolink:BiologicalProcess mesonephric glomerular visceral epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0061258 GO:0061259 biolink:BiologicalProcess mesonephric glomerular mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061259 CHEBI:90708 biolink:ChemicalSubstance retinoic acid receptor modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_90708 CHEBI:90709 biolink:ChemicalSubstance nuclear receptor modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_90709 CHEBI:90715 biolink:ChemicalSubstance 5,20-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90715 chebi_ph7_3 CHEBI:90716 biolink:ChemicalSubstance 8-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90716 chebi_ph7_3 CHEBI:90717 biolink:ChemicalSubstance 8,20-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90717 chebi_ph7_3 CHEBI:90718 biolink:ChemicalSubstance 12-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90718 chebi_ph7_3 CHEBI:90711 biolink:ChemicalSubstance 20-hydroxylipoxin B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90711 chebi_ph7_3 CHEBI:90710 biolink:ChemicalSubstance receptor modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_90710 GO:0051801 biolink:BiologicalProcess cytolysis in other organism involved in symbiotic interaction The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction. go-plus.json cytolysis of cells in other organism involved in symbiotic interaction|cytolysis of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051801 GO:0051802 biolink:BiologicalProcess regulation of cytolysis in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json regulation of cytolysis of cells in other organism during symbiotic interaction|regulation of cytolysis of cells in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051802 GO:0051800 biolink:MolecularActivity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate. Reactome:R-HSA-1676149|Reactome:R-HSA-1676204 go-plus.json PTEN activity http://purl.obolibrary.org/obo/GO_0051800 GO:0051805 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051805 GO:0051806 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051806 GO:0051803 biolink:BiologicalProcess negative regulation of cytolysis in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json down-regulation of cytolysis of cells in other organism during symbiotic interaction|inhibition of cytolysis of cells in other organism during symbiotic interaction|negative regulation of cytolysis of cells in other organism involved in symbiotic interaction|negative regulation of cytolysis of cells in other organism during symbiotic interaction|down regulation of cytolysis of cells in other organism during symbiotic interaction|downregulation of cytolysis of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051803 PR:000013526 biolink:Protein peptide YY A protein that is a translation product of the human PYY gene or a 1:1 ortholog thereof. go-plus.json peptide tyrosine tyrosine|PYY|PYY-I http://purl.obolibrary.org/obo/PR_000013526 GO:0051804 biolink:BiologicalProcess positive regulation of cytolysis in other organism involved in symbiotic interaction Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json up-regulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism during symbiotic interaction|upregulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism involved in symbiotic interaction|up regulation of cytolysis of cells in other organism during symbiotic interaction|activation of cytolysis of cells in other organism during symbiotic interaction|stimulation of cytolysis of cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051804 GO:0051809 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051809 GO:0051807 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051807 GO:0051808 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051808 CHEBI:90707 biolink:ChemicalSubstance 20-hydroxylipoxin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90707 chebi_ph7_3 CHEBI:89719 biolink:ChemicalSubstance propyl butyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_89719 chebi_ph7_3 CHEBI:65768 biolink:ChemicalSubstance (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65768 GO:0051812 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051812 GO:0051813 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051813 GO:0051810 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051810 GO:0051811 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051811 GO:0051816 biolink:BiologicalProcess acquisition of nutrients from other organism during symbiotic interaction The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051816 GO:0051817 biolink:BiologicalProcess modulation of process of other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of morphology or physiology of other organism during symbiotic interaction|regulation of physiological process in other organism during symbiotic interaction|regulation of physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism during symbiotic interaction|modulation of biological process of other organism involved in symbiotic interaction|regulation of morphology or physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism involved in symbiotic interaction|regulation of morphology of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051817 GO:0051814 biolink:BiologicalProcess obsolete movement in other organism involved in symbiotic interaction OBSOLETE. The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json movement within other organism during symbiotic interaction|movement in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051814 GO:0051815 biolink:BiologicalProcess obsolete migration in other organism involved in symbiotic interaction OBSOLETE. The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json migration within other organism during symbiotic interaction|migration in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051815 GO:0051818 biolink:BiologicalProcess disruption of cells of other organism involved in symbiotic interaction A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction. go-plus.json disruption of cells of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051818 GO:0051819 biolink:BiologicalProcess induction by symbiont of tumor or growth in host The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic. go-plus.json induction by symbiont of nodulation, tumor or growth in host|induction by symbiont in host of tumor, nodule, or growth containing transformed cells|induction of tumor, nodule, or growth containing transformed cells in other organism during symbiotic interaction|induction of tumor, nodule, or growth in other organism involved in symbiotic interaction|induction by symbiont in host of tumor, nodule, or growth|induction of tumor, nodule, or growth in other organism during symbiotic interaction|induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051819 GO:0036299 biolink:BiologicalProcess non-recombinational interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination. go-plus.json recombination-independent ICL repair|recombination-independent interstrand cross-link repair http://purl.obolibrary.org/obo/GO_0036299 CHEBI:90737 biolink:ChemicalSubstance 5-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90737 chebi_ph7_3 CHEBI:90736 biolink:ChemicalSubstance very long-chain acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90736 chebi_ph7_3 GO:0036291 biolink:BiologicalProcess protein cis-autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues. go-plus.json cis-autophosphorylation http://purl.obolibrary.org/obo/GO_0036291 GO:0036292 biolink:BiologicalProcess DNA rewinding The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA. go-plus.json RPA-dependent DNA rewinding|single-stranded DNA bubble rewinding|DNA annealing http://purl.obolibrary.org/obo/GO_0036292 GO:0036293 biolink:BiologicalProcess response to decreased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. go-plus.json response to lowered oxygen levels http://purl.obolibrary.org/obo/GO_0036293 GO:0036294 biolink:BiologicalProcess cellular response to decreased oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. go-plus.json cellular response to lowered oxygen levels http://purl.obolibrary.org/obo/GO_0036294 CHEBI:90732 biolink:ChemicalSubstance 20-hydroxy-6-trans-leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90732 chebi_ph7_3 GO:0036295 biolink:BiologicalProcess cellular response to increased oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. go-plus.json cellular response to raised oxygen levels http://purl.obolibrary.org/obo/GO_0036295 GO:0036296 biolink:BiologicalProcess response to increased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. go-plus.json response to raised oxygen levels http://purl.obolibrary.org/obo/GO_0036296 GO:0036297 biolink:BiologicalProcess interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. go-plus.json ICL repair http://purl.obolibrary.org/obo/GO_0036297 GO:0036298 biolink:BiologicalProcess recombinational interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region. go-plus.json recombination-dependent interstrand cross-link repair http://purl.obolibrary.org/obo/GO_0036298 GO:0051820 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051820 CHEBI:75105 biolink:ChemicalSubstance nonadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75105 chebi_ph7_3 CHEBI:75106 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75106 GO:0051823 biolink:BiologicalProcess regulation of synapse structural plasticity Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane. go-plus.json regulation of synaptic structural plasticity http://purl.obolibrary.org/obo/GO_0051823 GO:0051824 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051824 GO:0051821 biolink:BiologicalProcess obsolete dissemination or transmission of organism from other organism involved in symbiotic interaction OBSOLETE. The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism. go-plus.json dissemination or transmission of organism from other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051821 CHEBI:75109 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75109 GO:0036290 biolink:BiologicalProcess protein trans-autophosphorylation The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer. go-plus.json trans-autophosphorylation http://purl.obolibrary.org/obo/GO_0036290 GO:0051822 biolink:BiologicalProcess obsolete dissemination or transmission of organism from other organism by vector involved in symbiotic interaction OBSOLETE. The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal. go-plus.json dissemination or transmission of organism from other organism by vector during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051822 GO:0051827 biolink:BiologicalProcess obsolete growth or development on or near surface of other organism during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json growth or development on or near surface of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0051827 GO:0051828 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051828 GO:0051825 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051825 GO:0051826 biolink:BiologicalProcess negative regulation of synapse structural plasticity Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity. go-plus.json inhibition of synapse structural plasticity|down regulation of synapse structural plasticity|downregulation of synapse structural plasticity|down-regulation of synapse structural plasticity http://purl.obolibrary.org/obo/GO_0051826 GO:0120006 biolink:BiologicalProcess regulation of glutamatergic neuron differentiation Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0120006 CHEBI:90719 biolink:ChemicalSubstance 12,20-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90719 chebi_ph7_3 GO:0120007 biolink:BiologicalProcess negative regulation of glutamatergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0120007 GO:0120008 biolink:BiologicalProcess positive regulation of glutamatergic neuron differentiation Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0120008 GO:0051829 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051829 GO:0120009 biolink:BiologicalProcess intermembrane lipid transfer The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). go-plus.json http://purl.obolibrary.org/obo/GO_0120009 GO:0120002 biolink:CellularComponent fusiform vesicle A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0120002 GO:0036288 biolink:BiologicalProcess response to ximelagatran Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036288 gocheck_do_not_manually_annotate CHEBI:90726 biolink:ChemicalSubstance 3-oxoacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90726 chebi_ph7_3 GO:0120003 biolink:CellularComponent hinge region between urothelial plaques of apical plasma membrane A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0120003 GO:0036289 biolink:BiologicalProcess peptidyl-serine autophosphorylation The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein. go-plus.json serine autophosphorylation http://purl.obolibrary.org/obo/GO_0036289 CHEBI:90722 biolink:ChemicalSubstance 20-hydroxy-20-oxoleukotriene B4(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90722 chebi_ph7_3 CHEBI:90723 biolink:ChemicalSubstance 6-trans-leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90723 chebi_ph7_3 GO:0120001 biolink:CellularComponent apical plasma membrane urothelial plaque A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array. go-plus.json asymmetric unit membrane|AUM http://purl.obolibrary.org/obo/GO_0120001 CHEBI:90725 biolink:ChemicalSubstance very long-chain 3-oxoacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90725 chebi_ph7_3 GO:0036280 biolink:BiologicalProcess cellular response to L-canavanine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. go-plus.json http://purl.obolibrary.org/obo/GO_0036280 GO:0036281 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036281 GO:0036282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036282 CHEBI:90720 biolink:ChemicalSubstance 20-oxoleukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90720 chebi_ph7_3 GO:0036283 biolink:BiologicalProcess obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress. go-plus.json positive regulation of transcription factor import into nucleus in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_0036283 GO:0036284 biolink:CellularComponent tubulobulbar complex Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes. go-plus.json TBC http://purl.obolibrary.org/obo/GO_0036284 CHEBI:75103 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75103 GO:0036285 biolink:BiologicalProcess SAGA complex assembly The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof. go-plus.json SAGA complex formation http://purl.obolibrary.org/obo/GO_0036285 CHEBI:75104 biolink:ChemicalSubstance 1-oleoyl-2-nonadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75104 chebi_ph7_3 CHEBI:75101 biolink:ChemicalSubstance 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75101 GO:0036286 biolink:CellularComponent eisosome filament A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1. go-plus.json linear eisosome http://purl.obolibrary.org/obo/GO_0036286 GO:0036287 biolink:BiologicalProcess response to iloperidone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036287 gocheck_do_not_manually_annotate GO:0051830 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051830 CHEBI:75118 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75118 GO:0051831 biolink:BiologicalProcess obsolete growth or development in other organism during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism. go-plus.json growth or development within other organism during symbiotic interaction|growth or development in other organism during symbiotic interaction|invasive growth http://purl.obolibrary.org/obo/GO_0051831 CHEBI:75116 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75116 chebi_ph7_3 GO:0051834 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051834 GO:0051835 biolink:BiologicalProcess positive regulation of synapse structural plasticity Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity. go-plus.json up regulation of synapse structural plasticity|activation of synapse structural plasticity|stimulation of synapse structural plasticity|up-regulation of synapse structural plasticity|upregulation of synapse structural plasticity http://purl.obolibrary.org/obo/GO_0051835 GO:0051832 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051832 GO:0051833 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051833 GO:0051838 biolink:BiologicalProcess cytolysis by host of symbiont cells The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051838 GO:0051839 biolink:BiologicalProcess regulation by host of cytolysis of symbiont cells Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051839 GO:0051836 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051836 GO:0051837 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051837 GO:0036277 biolink:BiologicalProcess response to anticonvulsant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity. go-plus.json http://purl.obolibrary.org/obo/GO_0036277 gocheck_do_not_manually_annotate GO:0036278 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0036278 GO:0036279 biolink:BiologicalProcess positive regulation of protein export from nucleus in response to glucose starvation Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0036279 CHEBI:75110 biolink:ChemicalSubstance 1-acyl-2-linoleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75110 GO:0036270 biolink:BiologicalProcess response to diuretic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function. go-plus.json http://purl.obolibrary.org/obo/GO_0036270 gocheck_do_not_manually_annotate CHEBI:75111 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75111 chebi_ph7_3 GO:0036271 biolink:BiologicalProcess response to methylphenidate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus. go-plus.json response to MPD|response to ritalin|response to MPH http://purl.obolibrary.org/obo/GO_0036271 gocheck_do_not_manually_annotate GO:0036272 biolink:BiologicalProcess response to gemcitabine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas. go-plus.json response to 2'-deoxy-2',2'-difluorocytidine|response to 2',2'-difluorodeoxycytidine http://purl.obolibrary.org/obo/GO_0036272 gocheck_do_not_manually_annotate GO:0036273 biolink:BiologicalProcess response to statin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. go-plus.json response to HMG-CoA reductase inhibitor|response to hydroxymethylglutaryl-CoA reductase inhibitor http://purl.obolibrary.org/obo/GO_0036273 gocheck_do_not_manually_annotate GO:0036274 biolink:BiologicalProcess response to lapatinib Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036274 gocheck_do_not_manually_annotate GO:0036275 biolink:BiologicalProcess response to 5-fluorouracil Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus. go-plus.json response to fluorouracil|response to 5-fluoropyrimidine-2,4(1H,3H)-dione http://purl.obolibrary.org/obo/GO_0036275 gocheck_do_not_manually_annotate CHEBI:75112 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75112 GO:0036276 biolink:BiologicalProcess response to antidepressant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug. go-plus.json http://purl.obolibrary.org/obo/GO_0036276 gocheck_do_not_manually_annotate GO:0051841 biolink:BiologicalProcess positive regulation by host of cytolysis of symbiont cells Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json up-regulation by host of cytolysis of symbiont cells|upregulation by host of cytolysis of symbiont cells|up regulation by host of cytolysis of symbiont cells|activation by host of cytolysis of symbiont cells|stimulation by host of cytolysis of symbiont cells http://purl.obolibrary.org/obo/GO_0051841 GO:0051842 biolink:BiologicalProcess obsolete evasion or tolerance of symbiont immune response OBSOLETE. Any process, either active or passive, by which an organism avoids the effects of the symbiont organism's immune response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json immune evasion|evasion or tolerance of symbiont immune response http://purl.obolibrary.org/obo/GO_0051842 CHEBI:75127 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-D-galactosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_75127 GO:0051840 biolink:BiologicalProcess negative regulation by host of cytolysis of symbiont cells Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json down-regulation by host of cytolysis of symbiont cells|inhibition by host of cytolysis of symbiont cells|down regulation by host of cytolysis of symbiont cells|downregulation by host of cytolysis of symbiont cells http://purl.obolibrary.org/obo/GO_0051840 GO:0051845 biolink:BiologicalProcess obsolete passive evasion of symbiont immune response OBSOLETE. Any mechanism of immune avoidance that does not directly interfere with the symbiont immune system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json passive evasion of symbiont immune response|passive immune evasion http://purl.obolibrary.org/obo/GO_0051845 GO:0051846 biolink:BiologicalProcess obsolete active evasion of symbiont immune response OBSOLETE. Any mechanism of immune avoidance that directly affects the symbiont immune system, e.g. blocking any stage in symbiont MHC class I and II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json active evasion of symbiont immune response|active immune evasion http://purl.obolibrary.org/obo/GO_0051846 GO:0051843 biolink:BiologicalProcess obsolete evasion or tolerance of symbiont defense response OBSOLETE. Any process, either active or passive, by which an organism avoids or tolerates the effects of a symbiont organism's defense response. The symbiont defense response is mounted by the symbiont in response to the presence of the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json evasion or tolerance of symbiont defense response|evasion of symbiont defence response http://purl.obolibrary.org/obo/GO_0051843 GO:0051844 biolink:BiologicalProcess translocation of peptides or proteins into symbiont The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json transport of peptides or proteins into symbiont http://purl.obolibrary.org/obo/GO_0051844 GO:0051849 biolink:BiologicalProcess obsolete active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json active immune evasion via regulation of symbiont antigen processing or presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation|active immune evasion via modulation of symbiont antigen processing/presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation pathway|active immune evasion via modulation of symbiont antigen processing and presentation http://purl.obolibrary.org/obo/GO_0051849 GO:0051847 biolink:BiologicalProcess obsolete active evasion of symbiont immune response via regulation of symbiont complement system OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, symbiont macrophages, which are eventually destroyed. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json active immune evasion via regulation of symbiont complement system|active immune evasion via modulation of symbiont complement system|active evasion of symbiont immune response via regulation of symbiont complement system http://purl.obolibrary.org/obo/GO_0051847 GO:0051848 biolink:BiologicalProcess obsolete active evasion of symbiont immune response via regulation of symbiont cytokine network OBSOLETE. Any mechanism of active immune avoidance which works by regulating symbiont cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester symbiont cytokines and inhibit action. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json active immune evasion via regulation of symbiont cytokine network|active evasion of symbiont immune response via regulation of symbiont cytokine network|active immune evasion via modulation of symbiont cytokine network http://purl.obolibrary.org/obo/GO_0051848 GO:0036266 biolink:CellularComponent Cdc48p-Npl4p-Vms1p AAA ATPase complex A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p. go-plus.json Vms1-Cdc48-Npl4 complex|Vms1p-Cdc48p-Npl4p complex|Cdc48p-Npl4p-Vms1p complex http://purl.obolibrary.org/obo/GO_0036266 GO:0036267 biolink:BiologicalProcess invasive filamentous growth The growth of colonies in filamentous chains of cells into a substrate. go-plus.json invasive growth http://purl.obolibrary.org/obo/GO_0036267 CHEBI:90749 biolink:ChemicalSubstance antidote to cyanide poisoning go-plus.json http://purl.obolibrary.org/obo/CHEBI_90749 GO:0036268 biolink:BiologicalProcess swimming Self-propelled movement of an organism from one location to another through water, often by means of active fin movement. go-plus.json http://purl.obolibrary.org/obo/GO_0036268 GO:0036269 biolink:BiologicalProcess swimming behavior The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water. go-plus.json swimming behaviour http://purl.obolibrary.org/obo/GO_0036269 CHEBI:90740 biolink:ChemicalSubstance dihydronaphthalenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_90740 CHEBI:75121 biolink:ChemicalSubstance (11Z)-octadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75121 chebi_ph7_3 CHEBI:75122 biolink:ChemicalSubstance 1-oleoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75122 chebi_ph7_3 GO:0036260 biolink:BiologicalProcess RNA capping The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts. go-plus.json http://purl.obolibrary.org/obo/GO_0036260 GO:0036261 biolink:BiologicalProcess 7-methylguanosine cap hypermethylation Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation. go-plus.json m(7)G cap hypermethylation|hypermethylation of snRNA cap|snRNA capping|conversion of m(7)G to m(3)G|TMG cap formation|hypermethylation of snoRNA cap|2,2,7-trimethylguanosine cap formation|snoRNA capping http://purl.obolibrary.org/obo/GO_0036261 GO:0036262 biolink:BiologicalProcess granulysin production The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0036262 gocheck_do_not_annotate GO:0036263 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036263 GO:0036264 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036264 CHEBI:75123 biolink:ChemicalSubstance (6Z)-octadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75123 chebi_ph7_3 CHEBI:75124 biolink:ChemicalSubstance 1-oleoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75124 chebi_ph7_3 GO:0036265 biolink:BiologicalProcess RNA (guanine-N7)-methylation The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0036265 GO:0051852 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051852 GO:0051853 biolink:BiologicalProcess obsolete induction in symbiont of tumor, nodule, or growth OBSOLETE. The process by which an associated organism causes the formation of an abnormal mass of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction in symbiont of tumor, nodule, or growth http://purl.obolibrary.org/obo/GO_0051853 GO:0051850 biolink:BiologicalProcess acquisition of nutrients from symbiont The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051850 CHEBI:75139 biolink:ChemicalSubstance 2-oleoyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75139 chebi_ph7_3 GO:0051851 biolink:BiologicalProcess modulation by host of symbiont process The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modification by host of symbiont morphology or physiology http://purl.obolibrary.org/obo/GO_0051851 GO:0051856 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051856 GO:0051857 biolink:BiologicalProcess obsolete growth or development of organism on or near symbiont surface OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json growth or development of organism during interaction with symbiont|growth or development of organism on or near symbiont surface http://purl.obolibrary.org/obo/GO_0051857 GO:0051854 biolink:BiologicalProcess obsolete induction in symbiont of tumor, nodule, or growth containing transformed cells OBSOLETE. The process by which an organism causes the formation in its symbiont organism of an abnormal growth whose cells have been transformed and continue to exist in the absence of the first organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction in symbiont of tumor, nodule, or growth containing transformed cells http://purl.obolibrary.org/obo/GO_0051854 GO:0051855 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051855 GO:0051858 biolink:BiologicalProcess obsolete avoidance of symbiont defenses OBSOLETE. Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051858 GO:0051859 biolink:BiologicalProcess obsolete suppression of symbiont defenses OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051859 GO:0036255 biolink:BiologicalProcess response to methylamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036255 GO:0036256 biolink:BiologicalProcess cellular response to methylamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036256 GO:0036257 biolink:BiologicalProcess multivesicular body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. go-plus.json MVB organization http://purl.obolibrary.org/obo/GO_0036257 GO:0036258 biolink:BiologicalProcess multivesicular body assembly The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. go-plus.json multivesicular body biogenesis|MVB formation|MVB biogenesis http://purl.obolibrary.org/obo/GO_0036258 GO:0036259 biolink:BiologicalProcess aerobic raffinose catabolic process The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen. go-plus.json aerobic raffinose degradation|aerobic raffinose breakdown|aerobic raffinose catabolism http://purl.obolibrary.org/obo/GO_0036259 CHEBI:90778 biolink:ChemicalSubstance C-terminal Gly-Gly(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90778 chebi_ph7_3 CHEBI:90779 biolink:ChemicalSubstance S-substituted glutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90779 chebi_ph7_3 CHEBI:90774 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-mono(long-chain acyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90774 chebi_ph7_3 GO:0036250 biolink:BiologicalProcess peroxisome transport along microtubule The directed movement of a peroxisome along a microtubule, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0036250 CHEBI:90776 biolink:ChemicalSubstance 11-oxo-ETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_90776 GO:0036251 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to salt stress OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0036251 CHEBI:90770 biolink:ChemicalSubstance 3-(beta-D-galactosyl)mono(long-chain acyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90770 chebi_ph7_3 GO:0036252 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to menadione Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position. go-plus.json positive regulation of transcription from RNA polymerase II promoter in response to menadione stress http://purl.obolibrary.org/obo/GO_0036252 CHEBI:75137 biolink:ChemicalSubstance 2,2'-dilysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75137 chebi_ph7_3 CHEBI:75134 biolink:ChemicalSubstance 1-oleoyl-2-icosanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75134 GO:0036253 biolink:BiologicalProcess response to amiloride Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036253 CHEBI:90772 biolink:ChemicalSubstance 12(S)-HpEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90772 chebi_ph7_3 GO:0036254 biolink:BiologicalProcess cellular response to amiloride Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036254 GO:0051863 biolink:BiologicalProcess obsolete translocation of DNA into symbiont OBSOLETE. The directed movement of DNA from an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json translocation of DNA into symbiont http://purl.obolibrary.org/obo/GO_0051863 GO:0051864 biolink:MolecularActivity histone H3-methyl-lysine-36 demethylase activity Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. go-plus.json histone H3-lysine-36 demethylase activity|[histone-H3]-lysine-36 demethylase activity|histone-lysine (H3-K36) demethylase activity|histone-lysine demethylase activity (H3-K36 specific)|histone-lysine(H3-K36) demethylase activity|histone demethylase activity (H3-K36 specific)|histone H3K36 demethylase activity http://purl.obolibrary.org/obo/GO_0051864 GO:0051861 biolink:MolecularActivity glycolipid binding Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0051861 GO:0051862 biolink:BiologicalProcess translocation of molecules into symbiont The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json transport of molecules into symbiont http://purl.obolibrary.org/obo/GO_0051862 GO:0051867 biolink:BiologicalProcess general adaptation syndrome, behavioral process The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus. go-plus.json behavioural process during general adaptation syndrome|behavioural response during general adaptation syndrome|general adaptation syndrome, behavioral response|behavioral response during general adaptation syndrome|general adaptation syndrome, behavioural process|behavioral process during general adaptation syndrome|general adaptation syndrome, behavioural response http://purl.obolibrary.org/obo/GO_0051867 GO:0051868 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051868 GO:0051865 biolink:BiologicalProcess protein autoubiquitination The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink. go-plus.json protein self-ubiquitination|protein auto-ubiquitination|protein autoubiquitinylation|protein self-ubiquitinylation|protein auto-ubiquitinylation http://purl.obolibrary.org/obo/GO_0051865 GO:0051866 biolink:BiologicalProcess general adaptation syndrome General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses. go-plus.json general adaptation syndrome, physiological response|physiological process during general adaptation syndrome|general adaptation syndrome, physiological process|physiological response during general adaptation syndrome http://purl.obolibrary.org/obo/GO_0051866 GO:0051869 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051869 GO:0036244 biolink:BiologicalProcess cellular response to neutral pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json http://purl.obolibrary.org/obo/GO_0036244 GO:0036245 biolink:BiologicalProcess cellular response to menadione Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position. go-plus.json cellular response to vitamin K3 http://purl.obolibrary.org/obo/GO_0036245 GO:0036246 biolink:BiologicalProcess phytochelatin 2 import into vacuole The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. go-plus.json PC2 import into vacuole http://purl.obolibrary.org/obo/GO_0036246 GO:0036247 biolink:BiologicalProcess phytochelatin 3 import into vacuole The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. go-plus.json PC3 import into vacuole http://purl.obolibrary.org/obo/GO_0036247 GO:0036248 biolink:BiologicalProcess phytochelatin 4 import into vacuole The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. go-plus.json PC4 import into vacuole http://purl.obolibrary.org/obo/GO_0036248 GO:0036249 biolink:BiologicalProcess cadmium ion import into vacuole The directed movement of cadmium ions into the vacuole. go-plus.json vacuolar cadmium import http://purl.obolibrary.org/obo/GO_0036249 CHEBI:75140 biolink:ChemicalSubstance 2'-oleoylcardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75140 chebi_ph7_3 CHEBI:90768 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-monooctanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90768 chebi_ph7_3 CHEBI:90769 biolink:ChemicalSubstance 3-(beta-D-galactosyl)monooctanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90769 chebi_ph7_3 CHEBI:90762 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90762 chebi_ph7_3 CHEBI:90763 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl-(1->4)-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90763 chebi_ph7_3 CHEBI:75141 biolink:ChemicalSubstance 1-arachidonoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75141 GO:0036240 biolink:CellularComponent septal periplasm The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi. go-plus.json cell wall-enclosed septal periplasm http://purl.obolibrary.org/obo/GO_0036240 CHEBI:75147 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75147 chebi_ph7_3 GO:0036241 biolink:BiologicalProcess glutamate catabolic process to 4-hydroxybutyrate The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate. go-plus.json glutamate degradation to 4-hydroxybutyrate http://purl.obolibrary.org/obo/GO_0036241 CHEBI:75148 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75148 chebi_ph7_3 GO:0051860 biolink:BiologicalProcess obsolete evasion or tolerance of symbiont defenses OBSOLETE. The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051860 GO:0036242 biolink:BiologicalProcess glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase. MetaCyc:PWY-4321|MetaCyc:PWY3O-210 go-plus.json glutamate degradation via gamma aminobutyrate transaminase activity http://purl.obolibrary.org/obo/GO_0036242 CHEBI:51197 biolink:ChemicalSubstance calixaromatic go-plus.json http://purl.obolibrary.org/obo/CHEBI_51197 GO:0036243 biolink:MolecularActivity succinate-semialdehyde dehydrogenase (NADP+) activity Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+. RHEA:13213|EC:1.2.1.79 go-plus.json succinate semialdehyde:NADP+ oxidoreductase activity|succinic semialdehyde dehydrogenase (NADP+) activity|succinyl semialdehyde dehydrogenase (NADP+) activity|NADP-dependent succinate-semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0036243 CHEBI:90761 biolink:ChemicalSubstance 2-deoxy-D-ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_90761 chebi_ph7_3 CHEBI:75954 biolink:ChemicalSubstance vancomycin aglycone zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75954 CHEBI:75953 biolink:ChemicalSubstance devancoaminyl vancomycin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75953 chebi_ph7_3 CHEBI:75956 biolink:ChemicalSubstance galactosylceramide sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75956 chebi_ph7_3 CHEBI:51985 biolink:ChemicalSubstance alpha-linolenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_51985 CHEBI:75957 biolink:ChemicalSubstance dTDP-beta-L-4-epi-vancosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75957 chebi_ph7_3 UBERON:0013774 biolink:AnatomicalEntity diaphysis of metatarsal bone A diaphysis that is part of a metatarsal bone. go-plus.json shaft of metatarsal bone|diaphysis of metatarsal|metatarsal bone diaphysis|metatarsal diaphysis http://purl.obolibrary.org/obo/UBERON_0013774 CHEBI:61310 biolink:ChemicalSubstance chromium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61310 UBERON:0013772 biolink:AnatomicalEntity left nipple A nipple that is in_the_left_side_of a body proper. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013772 UBERON:0013773 biolink:AnatomicalEntity right nipple A nipple that is in_the_right_side_of a body proper. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013773 GO:0120299 biolink:MolecularActivity peptide histaminyltransferase activity Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein]. RHEA:66564 go-plus.json http://purl.obolibrary.org/obo/GO_0120299 CHEBI:61313 biolink:ChemicalSubstance C21-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61313 chebi_ph7_3 CHEBI:61314 biolink:ChemicalSubstance XTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61314 chebi_ph7_3 CHEBI:36347 biolink:ChemicalSubstance nuclear particle go-plus.json http://purl.obolibrary.org/obo/CHEBI_36347 CHEBI:36344 biolink:ChemicalSubstance hadron go-plus.json http://purl.obolibrary.org/obo/CHEBI_36344 CHEBI:61312 biolink:ChemicalSubstance 5-hydroxypseudobaptigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61312 GO:0120295 biolink:MolecularActivity histone serotonyltransferase activity Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+). go-plus.json http://purl.obolibrary.org/obo/GO_0120295 CHEBI:61317 biolink:ChemicalSubstance cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61317 CHEBI:61318 biolink:ChemicalSubstance cyanidin 3-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61318 GO:0120296 biolink:MolecularActivity peptide dopaminyltransferase activity Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+). RHEA:66556 go-plus.json http://purl.obolibrary.org/obo/GO_0120296 UBERON:0013768 biolink:AnatomicalEntity great vessel of heart Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart. go-plus.json great vessel of thorax|great vessel http://purl.obolibrary.org/obo/UBERON_0013768 UBERON:0013769 biolink:AnatomicalEntity uterine lumen A organ cavity that is part of a uterus. go-plus.json uterine space|cavity of uterus|uterine cavity http://purl.obolibrary.org/obo/UBERON_0013769 GO:0120297 biolink:MolecularActivity histone dopaminyltransferase activity Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+). go-plus.json http://purl.obolibrary.org/obo/GO_0120297 CHEBI:61316 biolink:ChemicalSubstance (3Z)-hex-3-en-1-yl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61316 chebi_ph7_3 GO:0120298 biolink:MolecularActivity peptide noradrenalinyltransferase activity Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+). RHEA:66560 go-plus.json http://purl.obolibrary.org/obo/GO_0120298 GO:0120291 biolink:BiologicalProcess negative regulation of mitotic recombination involved in replication fork processing Any process that inhibits or decreases the rate of mitotic DNA recombination during replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching. go-plus.json negative regulation of template switch recombination involved in replication fork processing|maintenance of template fidelity during replication fork processing|suppression of template switching during replication fork processing http://purl.obolibrary.org/obo/GO_0120291 GO:0120292 biolink:BiologicalProcess positive regulation of mitotic recombination-dependent replication fork processing Any process that activates or increases the frequency, rate or extent of replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart. go-plus.json positive regulation of homologous recombination dependent replication fork recovery|positive regulation of recombination-dependent DNA replication|positive regulation of homologous recombination-dependent replication fork processing http://purl.obolibrary.org/obo/GO_0120292 GO:0120293 biolink:CellularComponent dynein axonemal particle An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm. go-plus.json DynAP http://purl.obolibrary.org/obo/GO_0120293 GO:0120294 biolink:MolecularActivity peptide serotonyltransferase activity Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+). RHEA:66552 go-plus.json http://purl.obolibrary.org/obo/GO_0120294 CHEBI:36342 biolink:ChemicalSubstance subatomic particle go-plus.json http://purl.obolibrary.org/obo/CHEBI_36342 CHEBI:75950 biolink:ChemicalSubstance (20S)-protopanaxadiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75950 chebi_ph7_3 CHEBI:75951 biolink:ChemicalSubstance protopanaxatriol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75951 chebi_ph7_3 CHEBI:36343 biolink:ChemicalSubstance composite particle go-plus.json http://purl.obolibrary.org/obo/CHEBI_36343 CHEBI:36340 biolink:ChemicalSubstance fermion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36340 GO:0120290 biolink:BiologicalProcess stalled replication fork localization to nuclear periphery A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication. go-plus.json stalled replication fork localization to nuclear periphery involved in replication fork processing http://purl.obolibrary.org/obo/GO_0120290 CHEBI:36341 biolink:ChemicalSubstance boson go-plus.json http://purl.obolibrary.org/obo/CHEBI_36341 CHEBI:51978 biolink:ChemicalSubstance oxonium betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_51978 CHEBI:75963 biolink:ChemicalSubstance chloroorienticin B(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75963 chebi_ph7_3 CHEBI:51972 biolink:ChemicalSubstance 12'-apo-carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51972 chebi_ph7_3 CHEBI:51973 biolink:ChemicalSubstance 9-cis-epoxycarotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51973 chebi_ph7_3 CHEBI:75967 biolink:ChemicalSubstance nicotinate-adenine dinucleotide phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75967 chebi_ph7_3 UBERON:0013765 biolink:AnatomicalEntity digestive system element Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. go-plus.json digestive system organ|digestive organ http://purl.obolibrary.org/obo/UBERON_0013765 UBERON:0013760 biolink:AnatomicalEntity external cervical os Opening of uterine cervix into the vagina. go-plus.json external os|ostium uteri|external os of uterus|ostium of uterus http://purl.obolibrary.org/obo/UBERON_0013760 UBERON:0013761 biolink:AnatomicalEntity cervical cavity The cavity formed by the walls of the cervix. go-plus.json endocervical canal|cervical canal of uterus|cavity of cervix|endocervix|canal of the cervix|cervical canal|lumen of cervix of uterus|endocervical http://purl.obolibrary.org/obo/UBERON_0013761 CHEBI:36357 biolink:ChemicalSubstance polyatomic entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_36357 CHEBI:36358 biolink:ChemicalSubstance polyatomic ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36358 CHEBI:61323 biolink:ChemicalSubstance pratensein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61323 chebi_ph7_3 UBERON:0013756 biolink:AnatomicalEntity venous blood A blood that is part of a vein. go-plus.json blood in vein|venous blood|portion of venous blood http://purl.obolibrary.org/obo/UBERON_0013756 UBERON:0013757 biolink:AnatomicalEntity capillary blood A blood that is part of a capillary. go-plus.json portion of blood in capillary|blood in capillary|portion of capillary blood http://purl.obolibrary.org/obo/UBERON_0013757 UBERON:0013758 biolink:AnatomicalEntity cervical os One of two openings in the uterine cervix. go-plus.json cervical opening|uterine cervix opening http://purl.obolibrary.org/obo/UBERON_0013758 CHEBI:36359 biolink:ChemicalSubstance phosphorus oxoacid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_36359 CHEBI:75977 biolink:ChemicalSubstance (S)-2-hydroxyhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75977 CHEBI:51967 biolink:ChemicalSubstance monochlorobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51967 CHEBI:51961 biolink:ChemicalSubstance sesquarterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51961 CHEBI:51963 biolink:ChemicalSubstance hopanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51963 UBERON:0013752 biolink:AnatomicalEntity diaphysis of metacarpal bone A diaphysis that is part of a metacarpal bone. go-plus.json corpus ossis metacarpi|body of metacarpal|shaft of metacarpal bone|metacarpal bone diaphysis|shaft of metacarpal http://purl.obolibrary.org/obo/UBERON_0013752 UBERON:0013753 biolink:AnatomicalEntity distal epiphysis of metacarpal bone A distal epiphysis that is part of a metacarpal bone. go-plus.json distal end of metacarpal bone|lower end of metacarpal bone|caput ossis metacarpi|head of metacarpal bone http://purl.obolibrary.org/obo/UBERON_0013753 UBERON:0013754 biolink:AnatomicalEntity integumentary system layer A organ component layer that is part of a integumental system. go-plus.json layer of skin|skin layer http://purl.obolibrary.org/obo/UBERON_0013754 UBERON:0013755 biolink:AnatomicalEntity arterial blood A blood that is part of a artery. go-plus.json blood in artery|arterial blood|portion of arterial blood http://purl.obolibrary.org/obo/UBERON_0013755 UBERON:0013750 biolink:AnatomicalEntity metaphysis of tibia A metaphysis that is part of a tibia. go-plus.json tibial metaphysis http://purl.obolibrary.org/obo/UBERON_0013750 CHEBI:85300 biolink:ChemicalSubstance N(1),N(8)-bis(sinapoyl)-spermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85300 CHEBI:61330 biolink:ChemicalSubstance icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61330 chebi_ph7_3 CHEBI:85301 biolink:ChemicalSubstance N-(decanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85301 chebi_ph7_3 UBERON:0013749 biolink:AnatomicalEntity metaphysis of humerus A metaphysis that is part of a metaphysis. go-plus.json humeral metaphysis|diaphyseal end of humerus http://purl.obolibrary.org/obo/UBERON_0013749 CHEBI:85302 biolink:ChemicalSubstance N-(octanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85302 chebi_ph7_3 CHEBI:85303 biolink:ChemicalSubstance N-(hexanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85303 chebi_ph7_3 CHEBI:61336 biolink:ChemicalSubstance C4-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61336 CHEBI:85304 biolink:ChemicalSubstance N-(butanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85304 chebi_ph7_3 CHEBI:85305 biolink:ChemicalSubstance S-3-[(2R)-phycourobilin]-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85305 chebi_ph7_3 CHEBI:85306 biolink:ChemicalSubstance D-alloisoleucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85306 chebi_ph7_3 CHEBI:61339 biolink:ChemicalSubstance 5-hydroxypseudobaptigenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61339 chebi_ph7_3 CHEBI:36328 biolink:ChemicalSubstance HODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_36328 CHEBI:85307 biolink:ChemicalSubstance heparosan D-glucuronic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85307 chebi_ph7_3 CHEBI:36329 biolink:ChemicalSubstance HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_36329 CHEBI:36326 biolink:ChemicalSubstance octadecanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36326 CHEBI:85308 biolink:ChemicalSubstance heparosan L-iduronic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85308 chebi_ph7_3 CHEBI:61338 biolink:ChemicalSubstance bacillithiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61338 CHEBI:75972 biolink:ChemicalSubstance (R)-2-hydroxyhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75972 CHEBI:36321 biolink:ChemicalSubstance porphyrinogens go-plus.json http://purl.obolibrary.org/obo/CHEBI_36321 CHEBI:75970 biolink:ChemicalSubstance 2'-phospho-cyclic ADP-ribose(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75970 chebi_ph7_3 CHEBI:75989 biolink:ChemicalSubstance alpha-D-glucosamine 6-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75989 chebi_ph7_3 CHEBI:51958 biolink:ChemicalSubstance organic polycyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_51958 CHEBI:51959 biolink:ChemicalSubstance organic tricyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_51959 CHEBI:61346 biolink:ChemicalSubstance achromobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61346 chebi_ph7_3 CHEBI:36335 biolink:ChemicalSubstance trypanocidal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_36335 CHEBI:36336 biolink:ChemicalSubstance naphthalenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36336 CHEBI:36333 biolink:ChemicalSubstance local anaesthetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_36333 CHEBI:61344 biolink:ChemicalSubstance (S)-beta-macrocarpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61344 chebi_ph7_3 CHEBI:61345 biolink:ChemicalSubstance chrysobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61345 CHEBI:36334 biolink:ChemicalSubstance naphthalene-1,3,5-trisulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36334 CHEBI:36339 biolink:ChemicalSubstance baryon go-plus.json http://purl.obolibrary.org/obo/CHEBI_36339 CHEBI:12387 biolink:ChemicalSubstance beta-L-fucose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12387 CHEBI:36338 biolink:ChemicalSubstance lepton go-plus.json http://purl.obolibrary.org/obo/CHEBI_36338 CHEBI:36331 biolink:ChemicalSubstance octadeca-10,12-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36331 CHEBI:36330 biolink:ChemicalSubstance senecionan go-plus.json http://purl.obolibrary.org/obo/CHEBI_36330 CHEBI:26987 biolink:ChemicalSubstance threonine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_26987 CHEBI:75999 biolink:ChemicalSubstance (S)-laudanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75999 chebi_ph7_3 CHEBI:75996 biolink:ChemicalSubstance 2-arachidonoyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75996 chebi_ph7_3 CHEBI:26984 biolink:ChemicalSubstance threonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26984 CHEBI:26986 biolink:ChemicalSubstance threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26986 CHEBI:26980 biolink:ChemicalSubstance tetritol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26980 CHEBI:26981 biolink:ChemicalSubstance threitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26981 CHEBI:36309 biolink:ChemicalSubstance cyclic tetrapyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36309 GO:0120259 biolink:CellularComponent 7SK snRNP A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb. go-plus.json snRNP 7SK http://purl.obolibrary.org/obo/GO_0120259 GO:0120255 biolink:BiologicalProcess olefinic compound biosynthetic process The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). go-plus.json alkene substituted compound biosynthesis|alkene substituted compound biosynthetic process|alkene substituted compound anabolism|alkene substituted compound synthesis|alkene substituted compound anabolic process http://purl.obolibrary.org/obo/GO_0120255 CHEBI:36302 biolink:ChemicalSubstance icosa-5,8,12,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36302 GO:0120256 biolink:BiologicalProcess olefinic compound catabolic process The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). go-plus.json alkene substituted compound degradation|alkene substituted compound catabolism|alkene substituted compound breakdown|alkene substituted compound catabolic process http://purl.obolibrary.org/obo/GO_0120256 CHEBI:12336 biolink:ChemicalSubstance alpha-cyclopiazonic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_12336 GO:0120257 biolink:BiologicalProcess peptidyl-threonine acetylation The acetylation of peptidyl-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0120257 CHEBI:36300 biolink:ChemicalSubstance tricarboxylic acid dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36300 CHEBI:61355 biolink:ChemicalSubstance 3-hydroxy carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61355 GO:0120258 biolink:BiologicalProcess peptidyl-threonine O-acetylation The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine. RESID:AA0364 go-plus.json http://purl.obolibrary.org/obo/GO_0120258 CHEBI:36301 biolink:ChemicalSubstance ferroheme o go-plus.json http://purl.obolibrary.org/obo/CHEBI_36301 CHEBI:36306 biolink:ChemicalSubstance icosa-5,8,11,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36306 GO:0120251 biolink:BiologicalProcess hydrocarbon biosynthetic process The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only. go-plus.json hydrocarbon anabolism|hydrocarbon synthesis|hydrocarbon biosynthesis|hydrocarbon formation http://purl.obolibrary.org/obo/GO_0120251 GO:0120252 biolink:BiologicalProcess hydrocarbon metabolic process The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only. go-plus.json hydrocarbon metabolism http://purl.obolibrary.org/obo/GO_0120252 CHEBI:85329 biolink:ChemicalSubstance UDP-4-dehydro-6-deoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85329 chebi_ph7_3 CHEBI:36307 biolink:ChemicalSubstance glycosyl alditol go-plus.json http://purl.obolibrary.org/obo/CHEBI_36307 GO:0120253 biolink:BiologicalProcess hydrocarbon catabolic process The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only. go-plus.json hydrocarbon degradation|hydrocarbon breakdown|hydrocarbon catabolism http://purl.obolibrary.org/obo/GO_0120253 GO:0120254 biolink:BiologicalProcess olefinic compound metabolic process The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). go-plus.json alkene substituted compound metabolic process|alkene substituted compound metabolism http://purl.obolibrary.org/obo/GO_0120254 CHEBI:75990 biolink:ChemicalSubstance 2'-capryloylcardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75990 chebi_ph7_3 GO:0120250 biolink:MolecularActivity fatty acid omega-hydroxylase activity Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:39023 go-plus.json http://purl.obolibrary.org/obo/GO_0120250 CHEBI:75994 biolink:ChemicalSubstance 2'-palmitoylcardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75994 chebi_ph7_3 CHEBI:75995 biolink:ChemicalSubstance 2'-arachidonoylcardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75995 chebi_ph7_3 CHEBI:75992 biolink:ChemicalSubstance phenyl 5-phosphonato-alpha-D-ribofuranoside(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75992 chebi_ph7_3 CHEBI:75993 biolink:ChemicalSubstance 2-capryloyl-2'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75993 chebi_ph7_3 CHEBI:26995 biolink:ChemicalSubstance thromboxane go-plus.json http://purl.obolibrary.org/obo/CHEBI_26995 CHEBI:26996 biolink:ChemicalSubstance thromboxanes B go-plus.json http://purl.obolibrary.org/obo/CHEBI_26996 chebi_ph7_3 CHEBI:61360 biolink:ChemicalSubstance globoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_61360 CHEBI:26992 biolink:ChemicalSubstance threoses go-plus.json http://purl.obolibrary.org/obo/CHEBI_26992 CHEBI:61362 biolink:ChemicalSubstance cyclitol ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_61362 CHEBI:85311 biolink:ChemicalSubstance poly[(1->4)-beta-D-mannuronate] go-plus.json http://purl.obolibrary.org/obo/CHEBI_85311 chebi_ph7_3 CHEBI:85312 biolink:ChemicalSubstance beta-D-galacturonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85312 chebi_ph7_3 GO:0120266 biolink:BiologicalProcess positive regulation of chromosome attachment to the nuclear envelope Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope. go-plus.json stimulation of chromosome attachment to the nuclear envelope|up-regulation of chromosome attachment to the nuclear envelope|upregulation of chromosome attachment to the nuclear envelope|up regulation of chromosome attachment to the nuclear envelope|activation of chromosome attachment to the nuclear envelope http://purl.obolibrary.org/obo/GO_0120266 CHEBI:85313 biolink:ChemicalSubstance beta-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85313 chebi_ph7_3 CHEBI:36313 biolink:ChemicalSubstance glycerophosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36313 GO:0120267 biolink:CellularComponent pellicular membrane The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles. go-plus.json pellicle membrane|pellicular plasma membrane http://purl.obolibrary.org/obo/GO_0120267 CHEBI:36314 biolink:ChemicalSubstance glycerophosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36314 GO:0120268 biolink:BiologicalProcess paraflagellar rod assembly The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. go-plus.json PFR assembly|paraflagellar rod formation|paraflagellar rod biogenesis http://purl.obolibrary.org/obo/GO_0120268 CHEBI:36311 biolink:ChemicalSubstance corphinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36311 CHEBI:61366 biolink:ChemicalSubstance 2-tetradecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61366 GO:0120269 biolink:CellularComponent ciliary centrin arm A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0120269 CHEBI:36312 biolink:ChemicalSubstance sarpagan go-plus.json http://purl.obolibrary.org/obo/CHEBI_36312 CHEBI:85316 biolink:ChemicalSubstance (R)-ethylmalonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85316 chebi_ph7_3 GO:0120262 biolink:BiologicalProcess negative regulation of heterochromatin organization Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization. go-plus.json down regulation of heterochromatin organization|inhibition of heterochromatin organization|negative regulation of heterochromatin organization|down-regulation of heterochromatin organization|downregulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_0120262 CHEBI:85317 biolink:ChemicalSubstance D-galactaro-1,4-lactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85317 chebi_ph7_3 GO:0120263 biolink:BiologicalProcess positive regulation of heterochromatin organization Any process that activates or increases the frequency, rate or extent of heterochromatin organization. go-plus.json upregulation of heterochromatin organization|stimulation of heterochromatin organization|up-regulation of heterochromatin organization|activation of heterochromatin organization|positive regulation of heterochromatin organization|up regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_0120263 GO:0120264 biolink:BiologicalProcess regulation of chromosome attachment to the nuclear envelope Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0120264 CHEBI:36315 biolink:ChemicalSubstance glycerophosphoinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_36315 GO:0120265 biolink:BiologicalProcess negative regulation of chromosome attachment to the nuclear envelope Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope. go-plus.json down-regulation of chromosome attachment to the nuclear envelope|inhibition of chromosome attachment to the nuclear envelope|down regulation of chromosome attachment to the nuclear envelope|downregulation of chromosome attachment to the nuclear envelope http://purl.obolibrary.org/obo/GO_0120265 CHEBI:36316 biolink:ChemicalSubstance dipyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36316 GO:0120260 biolink:CellularComponent ciliary microtubule quartet A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape. go-plus.json ciliary MtQ http://purl.obolibrary.org/obo/GO_0120260 GO:0120261 biolink:BiologicalProcess regulation of heterochromatin organization Any process that modulates the frequency, rate, extent or location of heterochromatin organization. go-plus.json http://purl.obolibrary.org/obo/GO_0120261 CHEBI:36310 biolink:ChemicalSubstance glycosylglycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36310 CHEBI:51921 biolink:ChemicalSubstance heptadienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51921 CHEBI:26965 biolink:ChemicalSubstance thioglycines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26965 CHEBI:51922 biolink:ChemicalSubstance (E,E)-7-hydroxy-6-methylhepta-3,5-dienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51922 chebi_ph7_3 CHEBI:26961 biolink:ChemicalSubstance thiophenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_26961 CHEBI:85342 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85342 chebi_ph7_3 CHEBI:61375 biolink:ChemicalSubstance ferric-vibriobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61375 CHEBI:85344 biolink:ChemicalSubstance (4R)-3,4-dihydro-4-hydroxyphenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85344 CHEBI:85346 biolink:ChemicalSubstance N(3)-fumaroyl-(S)-2,3-diaminopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85346 GO:0120277 biolink:BiologicalProcess positive regulation of cerebral blood circulation Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. go-plus.json positive regulation of cerebrum blood circulation|up-regulation of cerebral blood circulation|activation of cerebral blood circulation|positive regulation of telencephalon blood circulation|up regulation of cerebral blood circulation|upregulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120277 CHEBI:12357 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_12357 chebi_ph7_3 GO:0120278 biolink:BiologicalProcess negative regulation of cerebral blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. go-plus.json negative regulation of cerebrum blood circulation|down-regulation of cerebral blood circulation|negative regulation of telencephalon blood circulation|downregulation of cerebral blood circulation|down regulation of cerebral blood circulation|inhibition of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120278 CHEBI:85347 biolink:ChemicalSubstance N(3)-fumaramoyl-(S)-2,3-diaminopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85347 GO:0120279 biolink:CellularComponent Z granule A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans. go-plus.json germline granule http://purl.obolibrary.org/obo/GO_0120279 CHEBI:61377 biolink:ChemicalSubstance TDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_61377 CHEBI:85348 biolink:ChemicalSubstance 11,12-saturated fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85348 CHEBI:85349 biolink:ChemicalSubstance CDP-1-stearoyl-2-arachidonoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85349 chebi_ph7_3 CHEBI:61378 biolink:ChemicalSubstance 2'-(5-triphosphoribosyl)-3'-dephospho-CoA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61378 chebi_ph7_3 GO:0120273 biolink:BiologicalProcess ciliary centrin arm assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules. go-plus.json ciliary centrin arm formation http://purl.obolibrary.org/obo/GO_0120273 GO:0120274 biolink:MolecularActivity virus coreceptor activity Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity. go-plus.json viral coreceptor activity http://purl.obolibrary.org/obo/GO_0120274 GO:0120275 biolink:BiologicalProcess cerebral blood circulation The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. go-plus.json telencephelon blood circulation|cerebrum blood circulation http://purl.obolibrary.org/obo/GO_0120275 GO:0120276 biolink:BiologicalProcess regulation of cerebral blood circulation Any process that modulates the frequency, rate or extent of cerebral blood circulation. go-plus.json regulation of telencephalon blood circulation|regulation of cerebrum blood circulation http://purl.obolibrary.org/obo/GO_0120276 GO:0120270 biolink:BiologicalProcess regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go-plus.json http://purl.obolibrary.org/obo/GO_0120270 CHEBI:12350 biolink:ChemicalSubstance beta-D-fructofuranose 2-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12350 GO:0120271 biolink:BiologicalProcess negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go-plus.json http://purl.obolibrary.org/obo/GO_0120271 GO:0120272 biolink:BiologicalProcess positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go-plus.json http://purl.obolibrary.org/obo/GO_0120272 CHEBI:26976 biolink:ChemicalSubstance thioribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_26976 CHEBI:26977 biolink:ChemicalSubstance thiosulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26977 CHEBI:26979 biolink:ChemicalSubstance organic heterotricyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_26979 CHEBI:26975 biolink:ChemicalSubstance thioribose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26975 CHEBI:61382 biolink:ChemicalSubstance dITP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61382 chebi_ph7_3 CHEBI:61383 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61383 chebi_ph7_3 CHEBI:61380 biolink:ChemicalSubstance acetylenic fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61380 CHEBI:85330 biolink:ChemicalSubstance dapdiamide A go-plus.json http://purl.obolibrary.org/obo/CHEBI_85330 CHEBI:61381 biolink:ChemicalSubstance D-mannitol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61381 chebi_ph7_3 CHEBI:61386 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alaninate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61386 chebi_ph7_3 CHEBI:51914 biolink:ChemicalSubstance organic heterohexacyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_51914 CHEBI:85331 biolink:ChemicalSubstance dapdiamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_85331 CHEBI:61387 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61387 chebi_ph7_3 CHEBI:51915 biolink:ChemicalSubstance indolocarbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_51915 CHEBI:85332 biolink:ChemicalSubstance dapdiamide B go-plus.json http://purl.obolibrary.org/obo/CHEBI_85332 CHEBI:85333 biolink:ChemicalSubstance dapdiamide C go-plus.json http://purl.obolibrary.org/obo/CHEBI_85333 CHEBI:61384 biolink:ChemicalSubstance sulfolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61384 CHEBI:61385 biolink:ChemicalSubstance UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61385 chebi_ph7_3 CHEBI:85334 biolink:ChemicalSubstance N,1-dipalmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85334 chebi_ph7_3 GO:0120288 biolink:BiologicalProcess negative regulation of aspartic endopeptidase activity, intramembrane cleaving Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120288 CHEBI:85335 biolink:ChemicalSubstance N,1-dipalmitoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85335 chebi_ph7_3 GO:0120289 biolink:BiologicalProcess positive regulation of aspartic endopeptidase activity, intramembrane cleaving Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120289 CHEBI:85336 biolink:ChemicalSubstance D-glucaro-1,4-lactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85336 chebi_ph7_3 CHEBI:61388 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61388 chebi_ph7_3 CHEBI:85337 biolink:ChemicalSubstance dapdiamide E go-plus.json http://purl.obolibrary.org/obo/CHEBI_85337 CHEBI:85338 biolink:ChemicalSubstance L-alloisoleucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85338 chebi_ph7_3 GO:0120284 biolink:MolecularActivity tryptophan binding Binding to 2-amino-3-(1H-indol-3-yl)propanoic acid. go-plus.json Trp binding http://purl.obolibrary.org/obo/GO_0120284 CHEBI:85339 biolink:ChemicalSubstance O-[S-(L-alloisoleucyl)pantetheine-4'-phosphoryl]serine zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85339 chebi_ph7_3 GO:0120285 biolink:MolecularActivity tyrosine sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of tyrosine. go-plus.json http://purl.obolibrary.org/obo/GO_0120285 GO:0120286 biolink:MolecularActivity tryptophan sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of tryptophan. go-plus.json http://purl.obolibrary.org/obo/GO_0120286 GO:0120287 biolink:BiologicalProcess regulation of aspartic endopeptidase activity, intramembrane cleaving Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120287 GO:0120280 biolink:CellularComponent ciliary pro-basal body The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium. go-plus.json flagellar pro-basal body|pro-basal body|probasal body|flagellar probasal body|pro-centriole http://purl.obolibrary.org/obo/GO_0120280 GO:0120281 biolink:CellularComponent autolysosome membrane A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0120281 GO:0120282 biolink:CellularComponent autolysosome lumen The volume that is enclosed within the autolysosome single-membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0120282 GO:0120283 biolink:MolecularActivity protein serine/threonine kinase binding Binding to a protein serine/threonine kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0120283 CHEBI:131436 biolink:ChemicalSubstance N-acetyl-L-phosphinothricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_131436 GO:1901169 biolink:BiologicalProcess 3-chlorocatechol biosynthetic process The chemical reactions and pathways resulting in the formation of 3-chlorocatechol. go-plus.json 3-chlorocatechol anabolism|3-chlorocatechol synthesis|3-chlorocatechol formation|3-chlorocatechol biosynthesis http://purl.obolibrary.org/obo/GO_1901169 GO:1901167 biolink:BiologicalProcess 3-chlorocatechol metabolic process The chemical reactions and pathways involving 3-chlorocatechol. go-plus.json 3-chlorocatechol metabolism http://purl.obolibrary.org/obo/GO_1901167 GO:1901168 biolink:BiologicalProcess 3-chlorocatechol catabolic process The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol. go-plus.json 3-chlorocatechol degradation|3-chlorocatechol breakdown|3-chlorocatechol catabolism http://purl.obolibrary.org/obo/GO_1901168 GO:1901165 biolink:BiologicalProcess positive regulation of trophoblast cell migration Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. go-plus.json up regulation of trophoblast cell migration|upregulation of trophoblast cell migration|up-regulation of trophoblast cell migration|activation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_1901165 GO:1901166 biolink:BiologicalProcess neural crest cell migration involved in autonomic nervous system development Any neural crest cell migration that is involved in autonomic nervous system development. go-plus.json http://purl.obolibrary.org/obo/GO_1901166 GO:1901174 biolink:BiologicalProcess phytoene biosynthetic process The chemical reactions and pathways resulting in the formation of phytoene. go-plus.json phytoene anabolism|phytoene synthesis|phytoene formation|phytoene biosynthesis http://purl.obolibrary.org/obo/GO_1901174 GO:1901175 biolink:BiologicalProcess lycopene metabolic process The chemical reactions and pathways involving lycopene. go-plus.json lycopene metabolism http://purl.obolibrary.org/obo/GO_1901175 GO:1901172 biolink:BiologicalProcess phytoene metabolic process The chemical reactions and pathways involving phytoene. go-plus.json phytoene metabolism http://purl.obolibrary.org/obo/GO_1901172 GO:1901173 biolink:BiologicalProcess phytoene catabolic process The chemical reactions and pathways resulting in the breakdown of phytoene. go-plus.json phytoene breakdown|phytoene catabolism|phytoene degradation http://purl.obolibrary.org/obo/GO_1901173 GO:1901170 biolink:BiologicalProcess naphthalene catabolic process The chemical reactions and pathways resulting in the breakdown of naphthalene. UM-BBD_pathwayID:naph go-plus.json naphthalene metabolism|naphthalene metabolic process|naphthalene catabolism|naphthalene degradation|naphthalene breakdown http://purl.obolibrary.org/obo/GO_1901170 GO:1901171 biolink:BiologicalProcess obsolete naphthalene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of naphthalene. go-plus.json naphthalene formation|naphthalene biosynthesis|naphthalene anabolism|naphthalene synthesis http://purl.obolibrary.org/obo/GO_1901171 GO:0061390 biolink:BiologicalProcess positive regulation of direction of cell growth Any process that increases the direction of cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0061390 CHEBI:131447 biolink:ChemicalSubstance 2-aminobenzoylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131447 chebi_ph7_3 GO:0061391 biolink:BiologicalProcess negative regulation of direction of cell growth Any process that decreases the direction of cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0061391 CHEBI:131448 biolink:ChemicalSubstance beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp go-plus.json http://purl.obolibrary.org/obo/CHEBI_131448 chebi_ph7_3 GO:0061392 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to osmotic stress OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061392 GO:0061393 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061393 GO:1901178 biolink:BiologicalProcess spheroidene metabolic process The chemical reactions and pathways involving spheroidene. go-plus.json spheroidene metabolism http://purl.obolibrary.org/obo/GO_1901178 GO:0061394 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. go-plus.json http://purl.obolibrary.org/obo/GO_0061394 GO:0061395 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. go-plus.json http://purl.obolibrary.org/obo/GO_0061395 GO:1901179 biolink:BiologicalProcess spheroidene catabolic process The chemical reactions and pathways resulting in the breakdown of spheroidene. go-plus.json spheroidene catabolism|spheroidene degradation|spheroidene breakdown http://purl.obolibrary.org/obo/GO_1901179 GO:1901176 biolink:BiologicalProcess lycopene catabolic process The chemical reactions and pathways resulting in the breakdown of lycopene. go-plus.json lycopene breakdown|lycopene degradation|lycopene catabolism http://purl.obolibrary.org/obo/GO_1901176 GO:0061396 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061396 GO:1901177 biolink:BiologicalProcess lycopene biosynthetic process The chemical reactions and pathways resulting in the formation of lycopene. go-plus.json lycopene biosynthesis|lycopene anabolism|lycopene synthesis|lycopene formation http://purl.obolibrary.org/obo/GO_1901177 GO:0061397 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to copper ion OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061397 GO:1901185 biolink:BiologicalProcess negative regulation of ERBB signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway. go-plus.json negative regulation of EGF receptor family signaling pathway|down-regulation of EGF receptor family signaling pathway|inhibition of ERBB signalling pathway|inhibition of ErbB signaling|down-regulation of ERBB signaling pathway|inhibition of EGFR family signaling pathway|down regulation of ERBB signalling pathway|downregulation of ERBB signaling pathway|downregulation of ERBB signalling pathway|inhibition of EGF receptor family signaling pathway|down-regulation of ErbB signaling|negative regulation of ErbB signaling|down regulation of EGFR family signaling pathway|down regulation of ERBB signaling pathway|inhibition of ERBB signaling pathway|downregulation of EGFR family signaling pathway|down regulation of EGF receptor family signaling pathway|down-regulation of ERBB signalling pathway|negative regulation of ERBB signalling pathway|downregulation of ErbB signaling|downregulation of EGF receptor family signaling pathway|down regulation of ErbB signaling|negative regulation of EGFR family signaling pathway|down-regulation of EGFR family signaling pathway http://purl.obolibrary.org/obo/GO_1901185 GO:0061398 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to copper ion OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061398 GO:1901186 biolink:BiologicalProcess positive regulation of ERBB signaling pathway Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway. go-plus.json upregulation of ErbB signaling|activation of EGF receptor family signaling pathway|up-regulation of EGFR family signaling pathway|upregulation of ERBB signalling pathway|up-regulation of ErbB signaling|up-regulation of EGF receptor family signaling pathway|up regulation of ERBB signaling pathway|upregulation of EGFR family signaling pathway|activation of ErbB signaling|up regulation of ERBB signalling pathway|upregulation of EGF receptor family signaling pathway|positive regulation of ErbB signaling|positive regulation of ERBB signalling pathway|upregulation of ERBB signaling pathway|up regulation of ErbB signaling|up regulation of EGFR family signaling pathway|activation of ERBB signalling pathway|positive regulation of EGFR family signaling pathway|up regulation of EGF receptor family signaling pathway|activation of ERBB signaling pathway|up-regulation of ERBB signaling pathway|positive regulation of EGF receptor family signaling pathway|activation of EGFR family signaling pathway|up-regulation of ERBB signalling pathway http://purl.obolibrary.org/obo/GO_1901186 GO:0061399 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061399 GO:1901183 biolink:BiologicalProcess positive regulation of camalexin biosynthetic process Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process. go-plus.json up regulation of camalexin biosynthesis|up regulation of camalexin anabolism|up regulation of camalexin biosynthetic process|positive regulation of camalexin anabolism|up regulation of camalexin synthesis|positive regulation of camalexin synthesis|up regulation of camalexin formation|activation of camalexin anabolism|positive regulation of camalexin formation|upregulation of camalexin biosynthesis|upregulation of camalexin biosynthetic process|activation of camalexin synthesis|up-regulation of camalexin anabolism|activation of camalexin formation|up-regulation of camalexin synthesis|up-regulation of camalexin biosynthesis|up-regulation of camalexin biosynthetic process|activation of camalexin biosynthetic process|up-regulation of camalexin formation|upregulation of camalexin anabolism|activation of camalexin biosynthesis|upregulation of camalexin synthesis|upregulation of camalexin formation|positive regulation of camalexin biosynthesis http://purl.obolibrary.org/obo/GO_1901183 GO:1901184 biolink:BiologicalProcess regulation of ERBB signaling pathway Any process that modulates the frequency, rate or extent of ERBB signaling pathway. go-plus.json regulation of ERBB signalling pathway|regulation of EGFR family signaling pathway|regulation of EGF receptor family signaling pathway|regulation of ErbB signaling http://purl.obolibrary.org/obo/GO_1901184 GO:1901181 biolink:BiologicalProcess negative regulation of cellular response to caffeine Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine. go-plus.json inhibition of cellular response to caffeine|down regulation of cellular response to caffeine|downregulation of cellular response to caffeine|down-regulation of cellular response to caffeine http://purl.obolibrary.org/obo/GO_1901181 GO:1901182 biolink:BiologicalProcess regulation of camalexin biosynthetic process Any process that modulates the frequency, rate or extent of camalexin biosynthetic process. go-plus.json regulation of camalexin synthesis|regulation of camalexin formation|regulation of camalexin biosynthesis|regulation of camalexin anabolism http://purl.obolibrary.org/obo/GO_1901182 CHEBI:131444 biolink:ChemicalSubstance guanidinoacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131444 CHEBI:131445 biolink:ChemicalSubstance 4-methylpentanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131445 chebi_ph7_3 GO:1901180 biolink:BiologicalProcess spheroidene biosynthetic process The chemical reactions and pathways resulting in the formation of spheroidene. go-plus.json spheroidene biosynthesis|spheroidene anabolism|spheroidene synthesis|spheroidene formation http://purl.obolibrary.org/obo/GO_1901180 CHEBI:131446 biolink:ChemicalSubstance 2-aminobenzoylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131446 chebi_ph7_3 GO:1901189 biolink:BiologicalProcess positive regulation of ephrin receptor signaling pathway Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway. go-plus.json up regulation of Eph receptor signalling pathway|upregulation of Eph receptor signaling pathway|positive regulation of Eph receptor signalling pathway|up regulation of ephrin receptor signaling pathway|activation of ephrin receptor signaling pathway|activation of Eph receptor signalling pathway|up-regulation of Eph receptor signaling pathway|up-regulation of Eph receptor signalling pathway|activation of Eph receptor signaling pathway|up-regulation of ephrin receptor signaling pathway|positive regulation of Eph receptor signaling pathway|up regulation of Eph receptor signaling pathway|upregulation of Eph receptor signalling pathway|upregulation of ephrin receptor signaling pathway http://purl.obolibrary.org/obo/GO_1901189 GO:1901187 biolink:BiologicalProcess regulation of ephrin receptor signaling pathway Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway. go-plus.json regulation of Eph receptor signalling pathway|regulation of Eph receptor signaling pathway http://purl.obolibrary.org/obo/GO_1901187 GO:1901188 biolink:BiologicalProcess negative regulation of ephrin receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway. go-plus.json down regulation of ephrin receptor signaling pathway|down regulation of Eph receptor signaling pathway|downregulation of Eph receptor signalling pathway|downregulation of ephrin receptor signaling pathway|inhibition of Eph receptor signaling pathway|down-regulation of Eph receptor signalling pathway|negative regulation of Eph receptor signalling pathway|down-regulation of ephrin receptor signaling pathway|inhibition of ephrin receptor signaling pathway|down-regulation of Eph receptor signaling pathway|negative regulation of Eph receptor signaling pathway|inhibition of Eph receptor signalling pathway|down regulation of Eph receptor signalling pathway|downregulation of Eph receptor signaling pathway http://purl.obolibrary.org/obo/GO_1901188 GO:1901196 biolink:BiologicalProcess positive regulation of calcium-mediated signaling involved in cellular response to salt stress Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress. go-plus.json up regulation of calcium-mediated signaling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular response to salt stress|up regulation of calcium-mediated signaling involved in cellular salinity response|activation of calcium-mediated signaling involved in cellular salinity response|stimulation of calcium-mediated signaling involved in cellular response to salt stress|positive regulation of calcium-mediated signaling involved in cellular salinity response|stimulation of calcium-mediated signaling involved in cellular salinity response|upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|positive regulation of calcium-mediated signalling involved in cellular response to ionic osmotic stress|stimulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular response to salt stress|up-regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to salt stress|positive regulation of calcium-mediated signalling involved in cellular salinity response|upregulation of calcium-mediated signaling involved in cellular response to salt stress|upregulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress http://purl.obolibrary.org/obo/GO_1901196 GO:1901197 biolink:BiologicalProcess positive regulation of calcium-mediated signaling involved in cellular response to calcium ion Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion. go-plus.json upregulation of calcium-mediated signaling involved in cellular response to calcium ion|positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up-regulation of calcium-mediated signaling involved in response to calcium ion|up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up regulation of calcium-mediated signaling involved in cellular response to calcium ion|activation of calcium-mediated signaling involved in cellular response to calcium ion|stimulation of calcium-mediated signaling involved in cellular response to calcium ion|upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion|stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to calcium ion http://purl.obolibrary.org/obo/GO_1901197 GO:1901194 biolink:BiologicalProcess negative regulation of formation of translation preinitiation complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex. go-plus.json down-regulation of formation of translation pre-initiation complex|negative regulation of formation of translation pre-initiation complex|downregulation of translation preinitiation complex assembly|downregulation of formation of translation preinitiation complex|down regulation of formation of translation preinitiation complex|down regulation of translation preinitiation complex assembly|inhibition of formation of translation pre-initiation complex|inhibition of formation of translation preinitiation complex|inhibition of translation preinitiation complex assembly|down regulation of formation of translation pre-initiation complex|downregulation of formation of translation pre-initiation complex|negative regulation of translation preinitiation complex assembly|down-regulation of formation of translation preinitiation complex|down-regulation of translation preinitiation complex assembly http://purl.obolibrary.org/obo/GO_1901194 GO:1901195 biolink:BiologicalProcess positive regulation of formation of translation preinitiation complex Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex. go-plus.json positive regulation of translation preinitiation complex assembly|activation of formation of translation pre-initiation complex|up regulation of formation of translation preinitiation complex|up regulation of translation preinitiation complex assembly|up-regulation of formation of translation pre-initiation complex|upregulation of translation preinitiation complex assembly|upregulation of formation of translation preinitiation complex|upregulation of formation of translation pre-initiation complex|up-regulation of translation preinitiation complex assembly|up-regulation of formation of translation preinitiation complex|activation of formation of translation preinitiation complex|up regulation of formation of translation pre-initiation complex|positive regulation of formation of translation pre-initiation complex|activation of translation preinitiation complex assembly http://purl.obolibrary.org/obo/GO_1901195 GO:1901192 biolink:BiologicalProcess positive regulation of formation of translation initiation ternary complex Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. go-plus.json up regulation of translation initiation ternary complex assembly|up regulation of formation of translation initiation ternary complex|positive regulation of translation initiation ternary complex assembly|activation of formation of translation initiation ternary complex|activation of translation initiation ternary complex assembly|up-regulation of formation of translation initiation ternary complex|up-regulation of translation initiation ternary complex assembly|upregulation of formation of translation initiation ternary complex|upregulation of translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_1901192 GO:1901193 biolink:BiologicalProcess regulation of formation of translation preinitiation complex Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex. go-plus.json regulation of translation preinitiation complex assembly|regulation of formation of translation pre-initiation complex http://purl.obolibrary.org/obo/GO_1901193 GO:1901190 biolink:BiologicalProcess regulation of formation of translation initiation ternary complex Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. go-plus.json regulation of translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_1901190 GO:1901191 biolink:BiologicalProcess negative regulation of formation of translation initiation ternary complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. go-plus.json down regulation of formation of translation initiation ternary complex|down regulation of translation initiation ternary complex assembly|downregulation of translation initiation ternary complex assembly|downregulation of formation of translation initiation ternary complex|down-regulation of formation of translation initiation ternary complex|negative regulation of translation initiation ternary complex assembly|down-regulation of translation initiation ternary complex assembly|inhibition of formation of translation initiation ternary complex|inhibition of translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_1901191 CHEBI:131429 biolink:ChemicalSubstance carcinine go-plus.json http://purl.obolibrary.org/obo/CHEBI_131429 GO:1901198 biolink:BiologicalProcess positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion. go-plus.json positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion http://purl.obolibrary.org/obo/GO_1901198 GO:1901199 biolink:BiologicalProcess positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress. go-plus.json positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|positive regulation of calcium ion transport into cytosol involved in cellular salinity response http://purl.obolibrary.org/obo/GO_1901199 CHEBI:9330 biolink:ChemicalSubstance sulfamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9330 CHEBI:75914 biolink:ChemicalSubstance 1-oleoyl-2-O-arachidonyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75914 chebi_ph7_3 CHEBI:75913 biolink:ChemicalSubstance 2-arachidonyl glyceryl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_75913 chebi_ph7_3 UBERON:0013727 biolink:AnatomicalEntity notochordal fluid Fluid contained within the notochordal canal go-plus.json notochord fluid|portion of notochordal fluid http://purl.obolibrary.org/obo/UBERON_0013727 CHEBI:36388 biolink:ChemicalSubstance saturated organic heterocyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_36388 CHEBI:36389 biolink:ChemicalSubstance saturated organic heteromonocyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_36389 CHEBI:36387 biolink:ChemicalSubstance chloroalkene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36387 CHEBI:75921 biolink:ChemicalSubstance (R,R)-2,3-dimethyl-6-phytylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75921 chebi_ph7_3 CHEBI:75920 biolink:ChemicalSubstance (R,R)-2-methyl-6-phytylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75920 chebi_ph7_3 CHEBI:9341 biolink:ChemicalSubstance sulfinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_9341 chebi_ph7_3 CHEBI:75925 biolink:ChemicalSubstance octadecanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_75925 chebi_ph7_3 CHEBI:75926 biolink:ChemicalSubstance 4-hydroxy-2-quinolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_75926 chebi_ph7_3 CHEBI:75923 biolink:ChemicalSubstance 3-oxodecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75923 chebi_ph7_3 CHEBI:75929 biolink:ChemicalSubstance D-cycloserine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75929 chebi_ph7_3 CHEBI:75927 biolink:ChemicalSubstance (R)-2-hydroxyhexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75927 chebi_ph7_3 CHEBI:75928 biolink:ChemicalSubstance (S)-2-hydroxyhexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75928 chebi_ph7_3 CHEBI:131401 biolink:ChemicalSubstance hexopyranosyl hexopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_131401 CHEBI:36393 biolink:ChemicalSubstance thiomorpholines go-plus.json http://purl.obolibrary.org/obo/CHEBI_36393 CHEBI:9337 biolink:ChemicalSubstance sulfathiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_9337 CHEBI:75932 biolink:ChemicalSubstance 26-desglucoavenacoside A go-plus.json http://purl.obolibrary.org/obo/CHEBI_75932 chebi_ph7_3 CHEBI:75933 biolink:ChemicalSubstance 4-O-(beta-L-Araf)-cis-L-Hyp go-plus.json http://purl.obolibrary.org/obo/CHEBI_75933 CHEBI:75931 biolink:ChemicalSubstance 26-desglucoavenacoside B go-plus.json http://purl.obolibrary.org/obo/CHEBI_75931 chebi_ph7_3 CHEBI:75936 biolink:ChemicalSubstance 1-O-palmityl-2-acetyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75936 chebi_ph7_3 CHEBI:75937 biolink:ChemicalSubstance monooleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75937 chebi_ph7_3 CHEBI:75935 biolink:ChemicalSubstance (R)-2-hydroxylignocerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75935 chebi_ph7_3 CHEBI:75938 biolink:ChemicalSubstance 3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75938 chebi_ph7_3 UBERON:0013701 biolink:AnatomicalEntity main body axis A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013701 UBERON:0013702 biolink:AnatomicalEntity body proper The region of the organism associated with the visceral organs. go-plus.json body|whole body http://purl.obolibrary.org/obo/UBERON_0013702 UBERON:0013703 biolink:AnatomicalEntity integumentary projection Anatomical projection that is part of the integumentl system. go-plus.json skin projection http://purl.obolibrary.org/obo/UBERON_0013703 UBERON:0013704 biolink:AnatomicalEntity notochordal canal A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily. go-plus.json chordal canal http://purl.obolibrary.org/obo/UBERON_0013704 CHEBI:36360 biolink:ChemicalSubstance phosphorus oxoacids and derivatives go-plus.json http://purl.obolibrary.org/obo/CHEBI_36360 CHEBI:36361 biolink:ChemicalSubstance phosphorous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36361 chebi_ph7_3 CHEBI:9300 biolink:ChemicalSubstance suberic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9300 CHEBI:36363 biolink:ChemicalSubstance hydroxyphosphanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36363 CHEBI:75947 biolink:ChemicalSubstance 2'-3'-cGAMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_75947 CHEBI:75945 biolink:ChemicalSubstance dioleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75945 chebi_ph7_3 CHEBI:75946 biolink:ChemicalSubstance cytochalasan alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75946 UBERON:0013700 biolink:AnatomicalEntity axial musculature Musculature of the head and neck, spine, and ribs. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013700 CHEBI:61302 biolink:ChemicalSubstance cerebronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61302 CHEBI:61301 biolink:ChemicalSubstance germacra-1(10),4,11(13)-trien-12-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61301 chebi_ph7_3 CHEBI:61307 biolink:ChemicalSubstance solavetivol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61307 chebi_ph7_3 CHEBI:61304 biolink:ChemicalSubstance phosphoglycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61304 CHEBI:61305 biolink:ChemicalSubstance germacra-1(10),4,11(13)-trien-12-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61305 GO:0051995 biolink:MolecularActivity Se-methyltransferase activity Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0051995 GO:0051996 biolink:MolecularActivity squalene synthase activity Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate. EC:2.5.1.21|MetaCyc:RXN66-281 go-plus.json squalene synthetase activity http://purl.obolibrary.org/obo/GO_0051996 GO:0051993 biolink:MolecularActivity abscisic acid glucose ester beta-glucosidase activity Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose. MetaCyc:RXN-11469|EC:3.2.1.175|RHEA:31347 go-plus.json ABA-GE beta-glucosidase activity http://purl.obolibrary.org/obo/GO_0051993 GO:0051994 biolink:MolecularActivity P-methyltransferase activity Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule. EC:2.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0051994 GO:0051999 biolink:BiologicalProcess mannosyl-inositol phosphorylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative. go-plus.json mannosyl-inositol phosphorylceramide biosynthesis|mannose-inositol-P-ceramide (MIPC) biosynthetic process|mannose inositol phosphoceramide biosynthetic process|MIPC biosynthetic process|mannosyl-inositol phosphorylceramide anabolism|mannosyl-inositol phosphorylceramide synthesis|mannosyl-inositol phosphorylceramide formation http://purl.obolibrary.org/obo/GO_0051999 GO:0051997 biolink:MolecularActivity 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2. KEGG_REACTION:R06604|RHEA:26301|MetaCyc:RXN-6201 go-plus.json OHCU decarboxylase activity|4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity http://purl.obolibrary.org/obo/GO_0051997 GO:0051998 biolink:MolecularActivity protein carboxyl O-methyltransferase activity Catalysis of the transfer of a methyl group to a carboxyl group on a protein. go-plus.json protein carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0051998 GO:2000104 biolink:BiologicalProcess negative regulation of DNA-dependent DNA replication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_2000104 NCBITaxon:226186 biolink:OrganismalEntity Bacteroides thetaiotaomicron VPI-5482 go-plus.json Bacteroides thetaiotaomicron str. VPI-5482|Bacteroides thetaiotaomicron strain VPI-5482 http://purl.obolibrary.org/obo/NCBITaxon_226186 GO:2000105 biolink:BiologicalProcess positive regulation of DNA-dependent DNA replication Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_2000105 GO:2000106 biolink:BiologicalProcess regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. go-plus.json regulation of leukocyte apoptosis http://purl.obolibrary.org/obo/GO_2000106 GO:2000107 biolink:BiologicalProcess negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. go-plus.json negative regulation of leukocyte apoptosis http://purl.obolibrary.org/obo/GO_2000107 GO:2000108 biolink:BiologicalProcess positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. go-plus.json positive regulation of leukocyte apoptosis http://purl.obolibrary.org/obo/GO_2000108 GO:2000109 biolink:BiologicalProcess regulation of macrophage apoptotic process Any process that modulates the frequency, rate or extent of macrophage apoptotic process. go-plus.json regulation of AICD|regulation of macrophage apoptosis|regulation of activation-induced cell death http://purl.obolibrary.org/obo/GO_2000109 GO:0061320 biolink:BiologicalProcess pericardial nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go-plus.json pericardial cell differentiation http://purl.obolibrary.org/obo/GO_0061320 GO:0036354 biolink:MolecularActivity 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+. RHEA:19733|MetaCyc:RXN-8787 go-plus.json http://purl.obolibrary.org/obo/GO_0036354 GO:0061321 biolink:BiologicalProcess garland nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go-plus.json garland cell differentiation http://purl.obolibrary.org/obo/GO_0061321 GO:0036355 biolink:MolecularActivity 2-iminoacetate synthase activity Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+. MetaCyc:RXN-11319|EC:4.1.99.19|RHEA:26361 go-plus.json http://purl.obolibrary.org/obo/GO_0036355 GO:0061322 biolink:BiologicalProcess disseminated nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061322 GO:0036356 biolink:MolecularActivity cyclic 2,3-diphosphoglycerate synthetase activity Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate. go-plus.json cDPGS activity|CPGS activity http://purl.obolibrary.org/obo/GO_0036356 GO:0061323 biolink:BiologicalProcess cell proliferation involved in heart morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061323 GO:0061324 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells. go-plus.json canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation http://purl.obolibrary.org/obo/GO_0061324 GO:0036357 biolink:MolecularActivity 2-phosphoglycerate kinase activity Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP. EC:2.7.2.- go-plus.json 2PGK activity http://purl.obolibrary.org/obo/GO_0036357 GO:2000100 biolink:BiologicalProcess regulation of establishment or maintenance of bipolar cell polarity regulating cell shape Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000100 GO:0061325 biolink:BiologicalProcess cell proliferation involved in outflow tract morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. go-plus.json http://purl.obolibrary.org/obo/GO_0061325 GO:0036358 biolink:BiologicalProcess lipoteichoic acid D-alanylation The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA). go-plus.json D-alanyl lipoteichoic acid formation|LTA D-alanylation|D-alanyl LTA formation http://purl.obolibrary.org/obo/GO_0036358 GO:2000101 biolink:BiologicalProcess regulation of mammary stem cell proliferation Any process that modulates the frequency, rate or extent of mammary stem cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000101 GO:0061326 biolink:BiologicalProcess renal tubule development The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0061326 GO:0036359 biolink:BiologicalProcess renal potassium excretion The elimination by an organism of potassium in the urine. go-plus.json renal K+ elimination|renal K(+) excretion|renal potassium ion excretion http://purl.obolibrary.org/obo/GO_0036359 GO:2000102 biolink:BiologicalProcess negative regulation of mammary stem cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000102 GO:0061327 biolink:BiologicalProcess anterior Malpighian tubule development The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. go-plus.json http://purl.obolibrary.org/obo/GO_0061327 GO:2000103 biolink:BiologicalProcess positive regulation of mammary stem cell proliferation Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000103 GO:0061328 biolink:BiologicalProcess posterior Malpighian tubule development The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. go-plus.json http://purl.obolibrary.org/obo/GO_0061328 GO:0061329 biolink:BiologicalProcess Malpighian tubule principal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061329 OBO:uberon/core#channel_for biolink:OntologyClass channel for channel_for go-plus.json carries http://purl.obolibrary.org/obo/uberon/core#channel_for GO:0051991 biolink:MolecularActivity UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP. EC:2.4.1.227|MetaCyc:NACGLCTRANS-RXN|RHEA:31227 go-plus.json http://purl.obolibrary.org/obo/GO_0051991 GO:0036350 biolink:BiologicalProcess mannose-specific flocculation The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other. go-plus.json cell-cell adhesion involved in mannose-specific flocculation http://purl.obolibrary.org/obo/GO_0036350 GO:0036351 biolink:BiologicalProcess histone H2A-K13 ubiquitination The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin. go-plus.json histone H2A ubiquitination (H2A-K13) http://purl.obolibrary.org/obo/GO_0036351 GO:0051992 biolink:MolecularActivity UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol. EC:2.7.8.13|MetaCyc:PHOSNACMURPENTATRANS-RXN|RHEA:28386 go-plus.json http://purl.obolibrary.org/obo/GO_0051992 goslim_chembl GO:0036352 biolink:BiologicalProcess histone H2A-K15 ubiquitination The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin. go-plus.json histone H2A ubiquitination (H2A-K15) http://purl.obolibrary.org/obo/GO_0036352 GO:0036353 biolink:BiologicalProcess histone H2A-K119 monoubiquitination The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms. go-plus.json histone H2A monoubiquitination (H2A-K119) http://purl.obolibrary.org/obo/GO_0036353 GO:0051990 biolink:MolecularActivity (R)-2-hydroxyglutarate dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. Reactome:R-HSA-880053|RHEA:38295|Reactome:R-HSA-880007|EC:1.1.99.39 go-plus.json D-2-hydroxyglutarate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0051990 GO:2000115 biolink:BiologicalProcess regulation of maintenance of bipolar cell polarity regulating cell shape Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000115 GO:2000116 biolink:BiologicalProcess regulation of cysteine-type endopeptidase activity Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity. go-plus.json regulation of lysosomal cysteine-type endopeptidase|regulation of thiol endopeptidase activity http://purl.obolibrary.org/obo/GO_2000116 GO:2000117 biolink:BiologicalProcess negative regulation of cysteine-type endopeptidase activity Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity. go-plus.json negative regulation of thiol endopeptidase activity|negative regulation of lysosomal cysteine-type endopeptidase http://purl.obolibrary.org/obo/GO_2000117 GO:2000118 biolink:BiologicalProcess regulation of sodium-dependent phosphate transport Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000118 GO:2000119 biolink:BiologicalProcess negative regulation of sodium-dependent phosphate transport Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000119 GO:0061310 biolink:BiologicalProcess canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation. go-plus.json canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development http://purl.obolibrary.org/obo/GO_0061310 GO:0036343 biolink:BiologicalProcess psychomotor behavior The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument. go-plus.json http://purl.obolibrary.org/obo/GO_0036343 GO:0061311 biolink:BiologicalProcess cell surface receptor signaling pathway involved in heart development Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time. go-plus.json cell surface receptor linked signaling pathway involved in heart development|cell surface receptor linked signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061311 GO:0036344 biolink:BiologicalProcess platelet morphogenesis Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. go-plus.json http://purl.obolibrary.org/obo/GO_0036344 GO:0061312 biolink:BiologicalProcess BMP signaling pathway involved in heart development A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time. go-plus.json BMP signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061312 GO:0036345 biolink:BiologicalProcess platelet maturation A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. go-plus.json http://purl.obolibrary.org/obo/GO_0036345 GO:0036346 biolink:BiologicalProcess cellular response to L-cysteine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration. go-plus.json http://purl.obolibrary.org/obo/GO_0036346 GO:2000110 biolink:BiologicalProcess negative regulation of macrophage apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. go-plus.json negative regulation of AICD|negative regulation of activation-induced cell death|negative regulation of macrophage apoptosis http://purl.obolibrary.org/obo/GO_2000110 GO:0061313 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in heart development The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time. go-plus.json fibroblast growth factor receptor signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061313 GO:0061314 biolink:BiologicalProcess Notch signaling involved in heart development The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time. go-plus.json Notch signalling involved in heart development http://purl.obolibrary.org/obo/GO_0061314 GO:0036347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036347 GO:2000111 biolink:BiologicalProcess positive regulation of macrophage apoptotic process Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. go-plus.json positive regulation of activation-induced cell death|positive regulation of AICD|positive regulation of macrophage apoptosis http://purl.obolibrary.org/obo/GO_2000111 GO:0036348 biolink:MolecularActivity hydantoin racemase activity Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin. EC:5.1.99.5|MetaCyc:RXN-9781|RHEA:46624|KEGG_REACTION:R09704 go-plus.json http://purl.obolibrary.org/obo/GO_0036348 GO:0061315 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells. go-plus.json canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0061315 GO:2000112 biolink:BiologicalProcess regulation of cellular macromolecule biosynthetic process Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. go-plus.json regulation of cellular macromolecule anabolism|regulation of cellular biopolymer biosynthetic process|regulation of cellular macromolecule synthesis|regulation of cellular macromolecule formation|regulation of cellular macromolecule biosynthesis http://purl.obolibrary.org/obo/GO_2000112 GO:2000113 biolink:BiologicalProcess negative regulation of cellular macromolecule biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process. go-plus.json negative regulation of cellular macromolecule biosynthesis|negative regulation of cellular macromolecule anabolism|negative regulation of cellular biopolymer biosynthetic process|negative regulation of cellular macromolecule synthesis|negative regulation of cellular macromolecule formation http://purl.obolibrary.org/obo/GO_2000113 GO:0036349 biolink:BiologicalProcess galactose-specific flocculation The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other. go-plus.json cell-cell adhesion involved in galactose-specific flocculation http://purl.obolibrary.org/obo/GO_0036349 GO:0061316 biolink:BiologicalProcess canonical Wnt signaling pathway involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt receptor signalling pathway involved in heart development|canonical Wnt-activated signaling pathway involved in heart development|canonical Wnt receptor signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061316 GO:0061317 biolink:BiologicalProcess canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment http://purl.obolibrary.org/obo/GO_0061317 GO:2000114 biolink:BiologicalProcess regulation of establishment of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. go-plus.json regulation of cell polarization|regulation of bud site selection/establishment of cell polarity http://purl.obolibrary.org/obo/GO_2000114 GO:0061318 biolink:BiologicalProcess renal filtration cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061318 GO:0061319 biolink:BiologicalProcess nephrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061319 GO:0036340 biolink:BiologicalProcess chitin-based cuticle sclerotization by biomineralization The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate. go-plus.json chitin-based cuticle hardening by biomineralisation http://purl.obolibrary.org/obo/GO_0036340 GO:0036341 biolink:BiologicalProcess chitin-based cuticle sclerotization by protein cross-linking The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle. go-plus.json chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning http://purl.obolibrary.org/obo/GO_0036341 GO:0036342 biolink:BiologicalProcess post-anal tail morphogenesis The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. go-plus.json http://purl.obolibrary.org/obo/GO_0036342 GO:1901109 biolink:BiologicalProcess granaticin biosynthetic process The chemical reactions and pathways resulting in the formation of granaticin. go-plus.json granaticin biosynthesis|granaticin anabolism|granaticin synthesis|granaticin formation http://purl.obolibrary.org/obo/GO_1901109 GO:1901107 biolink:BiologicalProcess granaticin metabolic process The chemical reactions and pathways involving granaticin. go-plus.json granaticin metabolism http://purl.obolibrary.org/obo/GO_1901107 GO:1901108 biolink:BiologicalProcess granaticin catabolic process The chemical reactions and pathways resulting in the breakdown of granaticin. go-plus.json granaticin catabolism|granaticin degradation|granaticin breakdown http://purl.obolibrary.org/obo/GO_1901108 GO:2000126 biolink:BiologicalProcess negative regulation of octopamine or tyramine signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway. go-plus.json negative regulation of octopamine/tyramine signaling pathway|negative regulation of octopamine or tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000126 GO:1901105 biolink:BiologicalProcess tetracenomycin C catabolic process The chemical reactions and pathways resulting in the breakdown of tetracenomycin C. go-plus.json tetracenomycin C degradation|tetracenomycin C breakdown|tetracenomycin C catabolism http://purl.obolibrary.org/obo/GO_1901105 GO:1901106 biolink:BiologicalProcess tetracenomycin C biosynthetic process The chemical reactions and pathways resulting in the formation of tetracenomycin C. go-plus.json tetracenomycin C biosynthesis|tetracenomycin C anabolism|tetracenomycin C synthesis|tetracenomycin C formation http://purl.obolibrary.org/obo/GO_1901106 GO:2000127 biolink:BiologicalProcess positive regulation of octopamine or tyramine signaling pathway Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway. go-plus.json positive regulation of octopamine or tyramine signalling pathway|positive regulation of octopamine/tyramine signaling pathway http://purl.obolibrary.org/obo/GO_2000127 GO:1901103 biolink:BiologicalProcess gramicidin S biosynthetic process The chemical reactions and pathways resulting in the formation of gramicidin S. go-plus.json gramicidin S anabolism|gramicidin S synthesis|gramicidin S formation|gramicidin S biosynthesis http://purl.obolibrary.org/obo/GO_1901103 GO:2000128 biolink:BiologicalProcess regulation of octopamine signaling pathway Any process that modulates the frequency, rate or extent of octopamine signaling pathway. go-plus.json regulation of octopamine signalling pathway http://purl.obolibrary.org/obo/GO_2000128 GO:1901104 biolink:BiologicalProcess tetracenomycin C metabolic process The chemical reactions and pathways involving tetracenomycin C. go-plus.json tetracenomycin C metabolism http://purl.obolibrary.org/obo/GO_1901104 GO:2000129 biolink:BiologicalProcess negative regulation of octopamine signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway. go-plus.json negative regulation of octopamine signalling pathway http://purl.obolibrary.org/obo/GO_2000129 GO:1901101 biolink:BiologicalProcess gramicidin S metabolic process The chemical reactions and pathways involving gramicidin S. go-plus.json gramicidin S metabolism http://purl.obolibrary.org/obo/GO_1901101 GO:1901102 biolink:BiologicalProcess gramicidin S catabolic process The chemical reactions and pathways resulting in the breakdown of gramicidin S. go-plus.json gramicidin S catabolism|gramicidin S degradation|gramicidin S breakdown http://purl.obolibrary.org/obo/GO_1901102 GO:0061340 biolink:BiologicalProcess establishment or maintenance of monopolar cell polarity regulating cell shape Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061340 GO:0061341 biolink:BiologicalProcess non-canonical Wnt signaling pathway involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time. go-plus.json non-canonical Wnt receptor signalling pathway involved in heart development|non-canonical Wnt receptor signaling pathway involved in heart development|non-canonical Wnt-activated signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0061341 GO:0061342 biolink:BiologicalProcess regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart. go-plus.json regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway http://purl.obolibrary.org/obo/GO_0061342 GO:0036332 biolink:MolecularActivity placental growth factor-activated receptor activity Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json PlGF receptor activity|placental growth factor receptor activity|PlGF-activated receptor activity http://purl.obolibrary.org/obo/GO_0036332 GO:0061343 biolink:BiologicalProcess cell adhesion involved in heart morphogenesis The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061343 GO:0036333 biolink:BiologicalProcess hepatocyte homeostasis Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. go-plus.json http://purl.obolibrary.org/obo/GO_0036333 GO:0061344 biolink:BiologicalProcess regulation of cell adhesion involved in heart morphogenesis Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061344 GO:2000120 biolink:BiologicalProcess positive regulation of sodium-dependent phosphate transport Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000120 GO:0036334 biolink:BiologicalProcess epidermal stem cell homeostasis Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0036334 GO:0061345 biolink:BiologicalProcess planar cell polarity pathway involved in cardiac muscle cell fate commitment The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0061345 GO:0061346 biolink:BiologicalProcess planar cell polarity pathway involved in heart morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061346 GO:0036335 biolink:BiologicalProcess intestinal stem cell homeostasis Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0036335 GO:2000121 biolink:BiologicalProcess regulation of removal of superoxide radicals Any process that modulates the frequency, rate or extent of removal of superoxide radicals. go-plus.json regulation of removal of oxygen free radicals|regulation of removal of O2- http://purl.obolibrary.org/obo/GO_2000121 GO:0061347 biolink:BiologicalProcess planar cell polarity pathway involved in outflow tract morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract. go-plus.json http://purl.obolibrary.org/obo/GO_0061347 GO:0036336 biolink:BiologicalProcess dendritic cell migration The movement of a dendritic cell within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0036336 GO:2000122 biolink:BiologicalProcess negative regulation of stomatal complex development Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development. go-plus.json http://purl.obolibrary.org/obo/GO_2000122 GO:0061348 biolink:BiologicalProcess planar cell polarity pathway involved in ventricular septum morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum. go-plus.json http://purl.obolibrary.org/obo/GO_0061348 GO:0036337 biolink:BiologicalProcess Fas signaling pathway A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily. go-plus.json FAS ligand-Fas signaling pathway|Apo-1 signaling pathway|Fas receptor signaling pathway|CD95 signaling pathway|FasL signaling pathway|FasR signaling pathway|Fas-FasL signaling pathway http://purl.obolibrary.org/obo/GO_0036337 GO:2000123 biolink:BiologicalProcess positive regulation of stomatal complex development Any process that activates or increases the frequency, rate or extent of stomatal complex development. go-plus.json http://purl.obolibrary.org/obo/GO_2000123 GO:2000124 biolink:BiologicalProcess regulation of endocannabinoid signaling pathway Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway. go-plus.json regulation of endocannabinoid signalling pathway http://purl.obolibrary.org/obo/GO_2000124 GO:0061349 biolink:BiologicalProcess planar cell polarity pathway involved in cardiac right atrium morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium. go-plus.json http://purl.obolibrary.org/obo/GO_0061349 GO:0036338 biolink:CellularComponent viral membrane The lipid bilayer of a virion, a complete fully infectious extracellular virus particle. go-plus.json http://purl.obolibrary.org/obo/GO_0036338 GO:2000125 biolink:BiologicalProcess regulation of octopamine or tyramine signaling pathway Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway. go-plus.json regulation of octopamine or tyramine signalling pathway|regulation of octopamine/tyramine signaling pathway http://purl.obolibrary.org/obo/GO_2000125 GO:0036339 biolink:BiologicalProcess lymphocyte adhesion to endothelial cell of high endothelial venule The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. go-plus.json lymphocyte adhesion to high endothelial venule|lymphocyte adhesion to HEV cell http://purl.obolibrary.org/obo/GO_0036339 CHEBI:9347 biolink:ChemicalSubstance sulfoglycolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9347 CHEBI:9349 biolink:ChemicalSubstance sulfonyldimethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_9349 chebi_ph7_3 GO:0036330 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036330 GO:0036331 biolink:BiologicalProcess avascular cornea development in camera-type eye The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees. go-plus.json avascular cornea development http://purl.obolibrary.org/obo/GO_0036331 GO:1901118 biolink:BiologicalProcess cephamycin C biosynthetic process The chemical reactions and pathways resulting in the formation of cephamycin C. go-plus.json cephamycin C anabolism|cephamycin C synthesis|cephamycin C formation|cephamycin C biosynthesis http://purl.obolibrary.org/obo/GO_1901118 GO:1901119 biolink:BiologicalProcess tobramycin metabolic process The chemical reactions and pathways involving tobramycin. go-plus.json tobramycin metabolism http://purl.obolibrary.org/obo/GO_1901119 GO:1901116 biolink:BiologicalProcess cephamycin C metabolic process The chemical reactions and pathways involving cephamycin C. go-plus.json cephamycin C metabolism http://purl.obolibrary.org/obo/GO_1901116 GO:2000137 biolink:BiologicalProcess negative regulation of cell proliferation involved in heart morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000137 GO:0036329 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036329 GO:1901117 biolink:BiologicalProcess cephamycin C catabolic process The chemical reactions and pathways resulting in the breakdown of cephamycin C. go-plus.json cephamycin C degradation|cephamycin C breakdown|cephamycin C catabolism http://purl.obolibrary.org/obo/GO_1901117 GO:2000138 biolink:BiologicalProcess positive regulation of cell proliferation involved in heart morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000138 GO:1901114 biolink:BiologicalProcess erythromycin catabolic process The chemical reactions and pathways resulting in the breakdown of erythromycin. go-plus.json erythromycin catabolism|erythromycin degradation|erythromycin breakdown http://purl.obolibrary.org/obo/GO_1901114 GO:2000139 biolink:BiologicalProcess regulation of octopamine signaling pathway involved in response to food Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food. go-plus.json regulation of octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_2000139 GO:1901115 biolink:BiologicalProcess erythromycin biosynthetic process The chemical reactions and pathways resulting in the formation of erythromycin. go-plus.json erythromycin formation|erythromycin biosynthesis|erythromycin anabolism|erythromycin synthesis http://purl.obolibrary.org/obo/GO_1901115 GO:1901112 biolink:BiologicalProcess actinorhodin biosynthetic process The chemical reactions and pathways resulting in the formation of actinorhodin. go-plus.json actinorhodin biosynthesis|actinorhodin anabolism|actinorhodin synthesis|actinorhodin formation http://purl.obolibrary.org/obo/GO_1901112 GO:1901113 biolink:BiologicalProcess erythromycin metabolic process The chemical reactions and pathways involving erythromycin. go-plus.json erythromycin metabolism http://purl.obolibrary.org/obo/GO_1901113 GO:1901110 biolink:BiologicalProcess actinorhodin metabolic process The chemical reactions and pathways involving actinorhodin. go-plus.json actinorhodin metabolism http://purl.obolibrary.org/obo/GO_1901110 GO:0061330 biolink:BiologicalProcess Malpighian tubule stellate cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0061330 GO:1901111 biolink:BiologicalProcess actinorhodin catabolic process The chemical reactions and pathways resulting in the breakdown of actinorhodin. go-plus.json actinorhodin degradation|actinorhodin breakdown|actinorhodin catabolism http://purl.obolibrary.org/obo/GO_1901111 GO:0061331 biolink:BiologicalProcess epithelial cell proliferation involved in Malpighian tubule morphogenesis The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061331 GO:0061332 biolink:BiologicalProcess Malpighian tubule bud morphogenesis The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. go-plus.json Malpighian tubule formation http://purl.obolibrary.org/obo/GO_0061332 GO:0036321 biolink:BiologicalProcess ghrelin secretion The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone. go-plus.json pancreatic ghrelin secretion http://purl.obolibrary.org/obo/GO_0036321 GO:0036322 biolink:BiologicalProcess pancreatic polypeptide secretion The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas. go-plus.json PP secretion http://purl.obolibrary.org/obo/GO_0036322 GO:0061333 biolink:BiologicalProcess renal tubule morphogenesis The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0061333 GO:2000130 biolink:BiologicalProcess positive regulation of octopamine signaling pathway Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway. go-plus.json positive regulation of octopamine signalling pathway http://purl.obolibrary.org/obo/GO_2000130 GO:1901120 biolink:BiologicalProcess tobramycin catabolic process The chemical reactions and pathways resulting in the breakdown of tobramycin. go-plus.json tobramycin degradation|tobramycin catabolism|tobramycin breakdown http://purl.obolibrary.org/obo/GO_1901120 GO:0061334 biolink:BiologicalProcess cell rearrangement involved in Malpighian tubule morphogenesis The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. go-plus.json cell migration involved in Malpighian tubule morphogenesis http://purl.obolibrary.org/obo/GO_0061334 GO:0036323 biolink:BiologicalProcess vascular endothelial growth factor receptor-1 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json FLT1 signaling pathway|VEGFR1 signaling pathway|VEGFR-1 signaling pathway http://purl.obolibrary.org/obo/GO_0036323 GO:2000131 biolink:BiologicalProcess regulation of tyramine signaling pathway Any process that modulates the frequency, rate or extent of tyramine signaling pathway. go-plus.json regulation of tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000131 GO:0036324 biolink:BiologicalProcess vascular endothelial growth factor receptor-2 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json VEGFR-2 signaling pathway|FLK-1 signaling pathway|VEGFR2 signaling pathway|KDR signaling pathway http://purl.obolibrary.org/obo/GO_0036324 GO:2000132 biolink:BiologicalProcess negative regulation of tyramine signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway. go-plus.json negative regulation of tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000132 GO:0061335 biolink:BiologicalProcess cell growth involved in Malpighian tubule morphogenesis The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061335 GO:0061336 biolink:BiologicalProcess cell morphogenesis involved in Malpighian tubule morphogenesis The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061336 GO:2000133 biolink:BiologicalProcess positive regulation of tyramine signaling pathway Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway. go-plus.json positive regulation of tyramine signalling pathway http://purl.obolibrary.org/obo/GO_2000133 GO:0036325 biolink:BiologicalProcess vascular endothelial growth factor receptor-3 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json VEGFR3 signaling pathway|FLT4 signaling pathway|VEGFR-3 signaling pathway http://purl.obolibrary.org/obo/GO_0036325 GO:0061337 biolink:BiologicalProcess cardiac conduction Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. go-plus.json http://purl.obolibrary.org/obo/GO_0061337 GO:0036326 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036326 GO:2000134 biolink:BiologicalProcess negative regulation of G1/S transition of mitotic cell cycle Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_2000134 GO:2000135 biolink:BiologicalProcess obsolete positive regulation of regulation of secondary heart field cardioblast proliferation OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation. go-plus.json positive regulation of regulation of secondary heart field cardioblast proliferation|positive regulation of regulation of second heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_2000135 GO:0061338 biolink:BiologicalProcess obsolete atrioventricular node impulse conduction delay OBSOLETE. A heart process that modulates the propagation of the signal that causes the heart muscle to contract. go-plus.json atrioventricular node impulse conduction delay http://purl.obolibrary.org/obo/GO_0061338 GO:0036327 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036327 GO:0061339 biolink:BiologicalProcess establishment or maintenance of monopolar cell polarity Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. go-plus.json http://purl.obolibrary.org/obo/GO_0061339 GO:0036328 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036328 GO:2000136 biolink:BiologicalProcess regulation of cell proliferation involved in heart morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000136 GO:0036320 biolink:MolecularActivity mating-type P-factor pheromone receptor activity Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus. go-plus.json P-factor receptor activity|P-factor mating pheromone receptor activity http://purl.obolibrary.org/obo/GO_0036320 GO:1901129 biolink:BiologicalProcess gentamycin catabolic process The chemical reactions and pathways resulting in the breakdown of gentamycin. go-plus.json gentamycin breakdown|gentamycin catabolism|gentamycin degradation http://purl.obolibrary.org/obo/GO_1901129 GO:1901127 biolink:BiologicalProcess candicidin biosynthetic process The chemical reactions and pathways resulting in the formation of candicidin. go-plus.json candicidin formation|candicidin biosynthesis|candicidin anabolism|candicidin synthesis http://purl.obolibrary.org/obo/GO_1901127 GO:0036318 biolink:MolecularActivity peptide pheromone receptor activity Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0036318 GO:0036319 biolink:MolecularActivity mating-type M-factor pheromone receptor activity Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus. go-plus.json M-factor mating pheromone receptor activity|M-factor receptor activity http://purl.obolibrary.org/obo/GO_0036319 GO:1901128 biolink:BiologicalProcess gentamycin metabolic process The chemical reactions and pathways involving gentamycin. go-plus.json gentamycin metabolism http://purl.obolibrary.org/obo/GO_1901128 GO:1901125 biolink:BiologicalProcess candicidin metabolic process The chemical reactions and pathways involving candicidin. go-plus.json candicidin metabolism http://purl.obolibrary.org/obo/GO_1901125 GO:1901126 biolink:BiologicalProcess candicidin catabolic process The chemical reactions and pathways resulting in the breakdown of candicidin. go-plus.json candicidin degradation|candicidin breakdown|candicidin catabolism http://purl.obolibrary.org/obo/GO_1901126 GO:0061360 biolink:BiologicalProcess optic chiasma development The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. go-plus.json optic chiasm development http://purl.obolibrary.org/obo/GO_0061360 GO:1901123 biolink:BiologicalProcess bacitracin A catabolic process The chemical reactions and pathways resulting in the breakdown of bacitracin A. go-plus.json bacitracin A degradation|bacitracin A breakdown|bacitracin A catabolism http://purl.obolibrary.org/obo/GO_1901123 GO:0061361 biolink:BiologicalProcess positive regulation of maintenance of bipolar cell polarity regulating cell shape Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_0061361 GO:1901124 biolink:BiologicalProcess bacitracin A biosynthetic process The chemical reactions and pathways resulting in the formation of bacitracin A. go-plus.json bacitracin A synthesis|bacitracin A formation|bacitracin A anabolism|bacitracin A biosynthesis http://purl.obolibrary.org/obo/GO_1901124 GO:0061362 biolink:BiologicalProcess negative regulation of maintenance of bipolar cell polarity regulating cell shape Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_0061362 GO:1901121 biolink:BiologicalProcess tobramycin biosynthetic process The chemical reactions and pathways resulting in the formation of tobramycin. go-plus.json tobramycin anabolism|tobramycin synthesis|tobramycin formation|tobramycin biosynthesis http://purl.obolibrary.org/obo/GO_1901121 GO:0061363 biolink:BiologicalProcess negative regulation of progesterone biosynthesis involved in luteolysis Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis. go-plus.json functional luteolysis http://purl.obolibrary.org/obo/GO_0061363 GO:1901122 biolink:BiologicalProcess bacitracin A metabolic process The chemical reactions and pathways involving bacitracin A. go-plus.json bacitracin A metabolism http://purl.obolibrary.org/obo/GO_1901122 GO:0061364 biolink:BiologicalProcess apoptotic process involved in luteolysis The apoptotic process that contributes to luteolysis. go-plus.json structural luteolysis|apoptosis involved in luteolysis http://purl.obolibrary.org/obo/GO_0061364 GO:0036310 biolink:MolecularActivity ATP-dependent DNA/DNA annealing activity An ATP-dependent activity that facilitates the formation of a complementary double-stranded DNA molecule. Reactome:R-HSA-5686642 go-plus.json DNA rewinding activity|nucleoside-triphosphatase activity involved in DNA annealing|ATP-dependent DNA annealing activity|annealing helicase activity http://purl.obolibrary.org/obo/GO_0036310 GO:1901130 biolink:BiologicalProcess gentamycin biosynthetic process The chemical reactions and pathways resulting in the formation of gentamycin. go-plus.json gentamycin anabolism|gentamycin synthesis|gentamycin formation|gentamycin biosynthesis http://purl.obolibrary.org/obo/GO_1901130 GO:0061365 biolink:BiologicalProcess positive regulation of triglyceride lipase activity Any process that increases the activity of triglyceride lipase. go-plus.json positive regulation of TAG activity http://purl.obolibrary.org/obo/GO_0061365 GO:0036311 biolink:MolecularActivity chitin disaccharide deacetylase activity Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate. go-plus.json chitin oligosaccharide amidohydrolase activity|chitobiose amidohydrolase activity|chitin oligosaccharide deacetylase activity http://purl.obolibrary.org/obo/GO_0036311 GO:1901131 biolink:BiologicalProcess kanamycin metabolic process The chemical reactions and pathways involving kanamycin. go-plus.json kanamycin metabolism http://purl.obolibrary.org/obo/GO_1901131 GO:0061366 biolink:BiologicalProcess behavioral response to chemical pain Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061366 GO:0061367 biolink:BiologicalProcess behavioral response to acetic acid induced pain Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061367 GO:0036312 biolink:MolecularActivity phosphatidylinositol 3-kinase regulatory subunit binding Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location. go-plus.json p85 binding|PI3K regulatory subunit binding http://purl.obolibrary.org/obo/GO_0036312 GO:0061368 biolink:BiologicalProcess behavioral response to formalin induced pain Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061368 GO:0036313 biolink:MolecularActivity phosphatidylinositol 3-kinase catalytic subunit binding Binding to the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring. go-plus.json p110 binding|PI3K catalytic subunit binding http://purl.obolibrary.org/obo/GO_0036313 GO:0061369 biolink:BiologicalProcess negative regulation of testicular blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle. go-plus.json negative regulation of testicular vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0061369 GO:0036314 biolink:BiologicalProcess response to sterol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036314 GO:0036315 biolink:BiologicalProcess cellular response to sterol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036315 GO:0036316 biolink:BiologicalProcess SREBP-SCAP complex retention in endoplasmic reticulum Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER. go-plus.json http://purl.obolibrary.org/obo/GO_0036316 GO:0036317 biolink:MolecularActivity tyrosyl-RNA phosphodiesterase activity Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis. go-plus.json unlinkase activity|VPg unlinkase activity|uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity|Y-pUpN PDE activity http://purl.obolibrary.org/obo/GO_0036317 GO:0036307 biolink:MolecularActivity 23S rRNA (adenine(2030)-N(6))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0036307 GO:1901138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901138 GO:0036308 biolink:MolecularActivity 16S rRNA (guanine(1516)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0036308 GO:1901139 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901139 GO:0036309 biolink:BiologicalProcess protein localization to M-band Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere. go-plus.json protein localization to M line|cellular protein localization to M-band|protein localization to mesophragma|protein localization to M disc http://purl.obolibrary.org/obo/GO_0036309 GO:1901136 biolink:BiologicalProcess carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. go-plus.json carbohydrate derivative degradation|carbohydrate derivative catabolism|carbohydrate derivative breakdown http://purl.obolibrary.org/obo/GO_1901136 GO:1901137 biolink:BiologicalProcess carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. go-plus.json carbohydrate derivative anabolism|carbohydrate derivative synthesis|carbohydrate derivative formation|carbohydrate derivative biosynthesis http://purl.obolibrary.org/obo/GO_1901137 GO:0061350 biolink:BiologicalProcess planar cell polarity pathway involved in cardiac muscle tissue morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0061350 GO:1901134 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901134 GO:0061351 biolink:BiologicalProcess neural precursor cell proliferation The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061351 GO:1901135 biolink:BiologicalProcess carbohydrate derivative metabolic process The chemical reactions and pathways involving carbohydrate derivative. go-plus.json carbohydrate derivative metabolism http://purl.obolibrary.org/obo/GO_1901135 goslim_mouse|goslim_agr GO:0061352 biolink:BiologicalProcess cell chemotaxis involved in Malpighian tubule morphogenesis The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0061352 GO:1901132 biolink:BiologicalProcess kanamycin catabolic process The chemical reactions and pathways resulting in the breakdown of kanamycin. go-plus.json kanamycin catabolism|kanamycin degradation|kanamycin breakdown http://purl.obolibrary.org/obo/GO_1901132 GO:1901133 biolink:BiologicalProcess kanamycin biosynthetic process The chemical reactions and pathways resulting in the formation of kanamycin. go-plus.json kanamycin anabolism|kanamycin synthesis|kanamycin formation|kanamycin biosynthesis http://purl.obolibrary.org/obo/GO_1901133 GO:0061353 biolink:BiologicalProcess BMP signaling pathway involved in Malpighian tubule cell chemotaxis A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule. go-plus.json bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis http://purl.obolibrary.org/obo/GO_0061353 GO:1901141 biolink:BiologicalProcess regulation of lignin biosynthetic process Any process that modulates the frequency, rate or extent of lignin biosynthetic process. go-plus.json regulation of lignin anabolism|regulation of lignin synthesis|regulation of lignin biosynthesis|regulation of lignin formation http://purl.obolibrary.org/obo/GO_1901141 GO:0061354 biolink:BiologicalProcess planar cell polarity pathway involved in pericardium morphogenesis The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium. go-plus.json http://purl.obolibrary.org/obo/GO_0061354 GO:1901142 biolink:BiologicalProcess insulin metabolic process The chemical reactions and pathways involving insulin. go-plus.json insulin metabolism http://purl.obolibrary.org/obo/GO_1901142 GO:0061355 biolink:BiologicalProcess Wnt protein secretion The controlled release of a Wnt protein from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061355 GO:0036300 biolink:BiologicalProcess B cell receptor internalization A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell. go-plus.json BCR receptor internalization|B cell receptor uptake of antigen|BCR endocytosis http://purl.obolibrary.org/obo/GO_0036300 GO:0036301 biolink:BiologicalProcess macrophage colony-stimulating factor production The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json M-CSF production http://purl.obolibrary.org/obo/GO_0036301 gocheck_do_not_annotate GO:0061356 biolink:BiologicalProcess regulation of Wnt protein secretion Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061356 GO:0036302 biolink:BiologicalProcess atrioventricular canal development The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0036302 GO:0061357 biolink:BiologicalProcess positive regulation of Wnt protein secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061357 GO:1901140 biolink:BiologicalProcess p-coumaryl alcohol transport The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json 4-hydroxycinnamyl alcohol transport http://purl.obolibrary.org/obo/GO_1901140 CHEBI:131487 biolink:ChemicalSubstance 1,2-diacyl-3-(alpha-D-6-sulfoquinovosyl)-sn-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131487 chebi_ph7_3 GO:0036303 biolink:BiologicalProcess lymph vessel morphogenesis The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0036303 GO:0061358 biolink:BiologicalProcess negative regulation of Wnt protein secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061358 GO:0061359 biolink:BiologicalProcess regulation of Wnt signaling pathway by Wnt protein secretion Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell. go-plus.json regulation of Wnt receptor signaling pathway by Wnt protein secretion|regulation of Wnt receptor signalling pathway by Wnt protein secretion|regulation of Wnt-activated signaling pathway by Wnt protein secretion http://purl.obolibrary.org/obo/GO_0061359 GO:0036304 biolink:BiologicalProcess umbilical cord morphogenesis The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0036304 GO:0036305 biolink:BiologicalProcess ameloblast differentiation The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. go-plus.json http://purl.obolibrary.org/obo/GO_0036305 GO:0036306 biolink:BiologicalProcess embryonic heart tube elongation The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. go-plus.json http://purl.obolibrary.org/obo/GO_0036306 GO:1901149 biolink:MolecularActivity salicylic acid binding Binding to salicylic acid. go-plus.json salicylic acid receptor http://purl.obolibrary.org/obo/GO_1901149 GO:0061380 biolink:BiologicalProcess superior colliculus development The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0061380 GO:0061381 biolink:BiologicalProcess cell migration in diencephalon The orderly movement of a cell that will reside in the diencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0061381 GO:1901147 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1901147 GO:0061382 biolink:BiologicalProcess Malpighian tubule tip cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061382 GO:1901148 biolink:BiologicalProcess gene expression involved in extracellular matrix organization Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. go-plus.json extracellular matrix protein production|expression of extracellular matrix proteins http://purl.obolibrary.org/obo/GO_1901148 GO:1901145 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in nephron morphogenesis Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1901145 GO:0061383 biolink:BiologicalProcess trabecula morphogenesis The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0061383 GO:0061384 biolink:BiologicalProcess heart trabecula morphogenesis The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0061384 GO:1901146 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1901146 GO:1901143 biolink:BiologicalProcess insulin catabolic process The chemical reactions and pathways resulting in the breakdown of insulin. go-plus.json insulin degradation|insulin breakdown|insulin catabolism http://purl.obolibrary.org/obo/GO_1901143 GO:0061385 biolink:BiologicalProcess fibroblast proliferation involved in heart morphogenesis The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061385 GO:1901144 biolink:BiologicalProcess obsolete insulin biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin. go-plus.json insulin formation|insulin biosynthetic process|insulin anabolism|insulin biosynthesis|insulin synthesis http://purl.obolibrary.org/obo/GO_1901144 GO:0061386 biolink:BiologicalProcess closure of optic fissure The closure of the temporary ventral gap in the optic cup that contributes to its shaping. go-plus.json closure or choriod fissure http://purl.obolibrary.org/obo/GO_0061386 GO:1901152 biolink:BiologicalProcess vistamycin biosynthetic process The chemical reactions and pathways resulting in the formation of vistamycin. go-plus.json vistamycin anabolism|vistamycin synthesis|vistamycin formation|vistamycin biosynthesis|ribostamycin anabolism|ribostamycin synthesis|ribostamycin formation|ribostamycin biosynthetic process|ribostamycin biosynthesis http://purl.obolibrary.org/obo/GO_1901152 GO:0061387 biolink:BiologicalProcess regulation of extent of cell growth Any process that modulates the extent of cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0061387 CHEBI:131450 biolink:ChemicalSubstance 2,6-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131450 chebi_ph7_3 GO:0061388 biolink:BiologicalProcess regulation of rate of cell growth Any process that modulates the rate of cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0061388 GO:1901153 biolink:BiologicalProcess paromomycin metabolic process The chemical reactions and pathways involving paromomycin. go-plus.json paromomycin metabolism http://purl.obolibrary.org/obo/GO_1901153 GO:1901150 biolink:BiologicalProcess vistamycin metabolic process The chemical reactions and pathways involving vistamycin. go-plus.json ribostamycin metabolic process|vistamycin metabolism|ribostamycin metabolism http://purl.obolibrary.org/obo/GO_1901150 GO:0061389 biolink:BiologicalProcess regulation of direction of cell growth Any process that modulates the direction of cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0061389 GO:1901151 biolink:BiologicalProcess vistamycin catabolic process The chemical reactions and pathways resulting in the breakdown of vistamycin. go-plus.json ribostamycin degradation|ribostamycin breakdown|vistamycin catabolism|ribostamycin catabolic process|vistamycin degradation|ribostamycin catabolism|vistamycin breakdown http://purl.obolibrary.org/obo/GO_1901151 GO:1901158 biolink:BiologicalProcess neomycin biosynthetic process The chemical reactions and pathways resulting in the formation of neomycin. go-plus.json neomycin biosynthesis|neomycin anabolism|neomycin synthesis|neomycin formation http://purl.obolibrary.org/obo/GO_1901158 GO:0061370 biolink:BiologicalProcess testosterone biosynthetic process The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. go-plus.json http://purl.obolibrary.org/obo/GO_0061370 GO:0061371 biolink:BiologicalProcess determination of heart left/right asymmetry Determination of the asymmetric location of the heart with respect to the left and right halves of the organism. go-plus.json determination of cardiac left/right asymmetry http://purl.obolibrary.org/obo/GO_0061371 GO:1901159 biolink:BiologicalProcess xylulose 5-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate. go-plus.json xylulose 5-phosphate biosynthesis|xylulose 5-phosphate anabolism|xylulose 5-phosphate synthesis|xylulose 5-phosphate formation http://purl.obolibrary.org/obo/GO_1901159 GO:1901156 biolink:BiologicalProcess neomycin metabolic process The chemical reactions and pathways involving neomycin. go-plus.json neomycin metabolism http://purl.obolibrary.org/obo/GO_1901156 GO:0061372 biolink:BiologicalProcess activin receptor signaling pathway involved in heart jogging A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging. go-plus.json activin receptor signalling pathway involved in heart jogging http://purl.obolibrary.org/obo/GO_0061372 GO:1901157 biolink:BiologicalProcess neomycin catabolic process The chemical reactions and pathways resulting in the breakdown of neomycin. go-plus.json neomycin catabolism|neomycin degradation|neomycin breakdown http://purl.obolibrary.org/obo/GO_1901157 GO:0061373 biolink:BiologicalProcess mammillary axonal complex development The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0061373 GO:0061374 biolink:BiologicalProcess mammillothalamic axonal tract development The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit. go-plus.json http://purl.obolibrary.org/obo/GO_0061374 GO:1901154 biolink:BiologicalProcess paromomycin catabolic process The chemical reactions and pathways resulting in the breakdown of paromomycin. go-plus.json paromomycin catabolism|paromomycin degradation|paromomycin breakdown http://purl.obolibrary.org/obo/GO_1901154 GO:1901155 biolink:BiologicalProcess paromomycin biosynthetic process The chemical reactions and pathways resulting in the formation of paromomycin. go-plus.json paromomycin anabolism|paromomycin biosynthesis|paromomycin synthesis|paromomycin formation http://purl.obolibrary.org/obo/GO_1901155 GO:0061375 biolink:BiologicalProcess mammillotectal axonal tract development The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. go-plus.json http://purl.obolibrary.org/obo/GO_0061375 GO:1901163 biolink:BiologicalProcess regulation of trophoblast cell migration Any process that modulates the frequency, rate or extent of trophoblast cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_1901163 GO:0061376 biolink:BiologicalProcess mammillotegmental axonal tract development The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons. go-plus.json http://purl.obolibrary.org/obo/GO_0061376 GO:0061377 biolink:BiologicalProcess mammary gland lobule development The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. go-plus.json http://purl.obolibrary.org/obo/GO_0061377 GO:1901164 biolink:BiologicalProcess negative regulation of trophoblast cell migration Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. go-plus.json downregulation of trophoblast cell migration|down regulation of trophoblast cell migration|inhibition of trophoblast cell migration|down-regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_1901164 GO:1901161 biolink:BiologicalProcess primary amino compound catabolic process The chemical reactions and pathways resulting in the breakdown of primary amino compound. go-plus.json primary amino compound degradation|primary amino compound breakdown|primary amino compound catabolism http://purl.obolibrary.org/obo/GO_1901161 GO:0061378 biolink:BiologicalProcess corpora quadrigemina development The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi. go-plus.json http://purl.obolibrary.org/obo/GO_0061378 GO:0061379 biolink:BiologicalProcess inferior colliculus development The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally. go-plus.json http://purl.obolibrary.org/obo/GO_0061379 GO:1901162 biolink:BiologicalProcess primary amino compound biosynthetic process The chemical reactions and pathways resulting in the formation of primary amino compound. go-plus.json primary amino compound anabolism|primary amino compound biosynthesis|primary amino compound synthesis|primary amino compound formation http://purl.obolibrary.org/obo/GO_1901162 GO:1901160 biolink:BiologicalProcess primary amino compound metabolic process The chemical reactions and pathways involving primary amino compound. go-plus.json primary amino compound metabolism http://purl.obolibrary.org/obo/GO_1901160 CHEBI:9398 biolink:ChemicalSubstance tamsulosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9398 CHEBI:26945 biolink:ChemicalSubstance thiamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26945 GO:0051911 biolink:MolecularActivity Methanosarcina-phenazine hydrogenase activity Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine. EC:1.12.98.3|MetaCyc:RXN-7733|RHEA:24436 go-plus.json methylviologen-reducing hydrogenase activity|methanophenazine hydrogenase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051911 GO:0051912 biolink:MolecularActivity CoB--CoM heterodisulfide reductase activity Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine. EC:1.8.98.1|MetaCyc:1.8.98.1-RXN|RHEA:18085 go-plus.json soluble heterodisulfide reductase activity|coenzyme B--coenzyme M heterodisulfide reductase activity|CoB-CoM heterodisulfide reductase activity|heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|coenzyme B:coenzyme M:methanophenazine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051912 GO:0051910 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051910 GO:0051915 biolink:BiologicalProcess induction of synaptic plasticity by chemical substance The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require. go-plus.json induction of synaptic plasticity by drug|activation of synaptic plasticity by drug|activation of synaptic plasticity by chemical substance http://purl.obolibrary.org/obo/GO_0051915 GO:0051916 biolink:MolecularActivity granulocyte colony-stimulating factor binding Binding to granulocyte colony-stimulating factor, G-CSF. go-plus.json G-CSF binding|granulocyte colony stimulating factor binding http://purl.obolibrary.org/obo/GO_0051916 GO:0051913 biolink:BiologicalProcess regulation of synaptic plasticity by chemical substance The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require. go-plus.json regulation of synaptic plasticity by drug http://purl.obolibrary.org/obo/GO_0051913 CHEBI:85241 biolink:ChemicalSubstance 1-monooctanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85241 chebi_ph7_3 GO:0051914 biolink:BiologicalProcess positive regulation of synaptic plasticity by chemical substance The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require. go-plus.json up-regulation of synaptic plasticity by chemical substance|upregulation of synaptic plasticity by chemical substance|positive regulation of synaptic plasticity by drug|up regulation of synaptic plasticity by chemical substance|activation of synaptic plasticity by chemical substance|stimulation of synaptic plasticity by chemical substance http://purl.obolibrary.org/obo/GO_0051914 GO:0051919 biolink:BiologicalProcess positive regulation of fibrinolysis Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. go-plus.json up-regulation of fibrinolysis|activation of fibrinolysis|up regulation of fibrinolysis|upregulation of fibrinolysis|stimulation of fibrinolysis http://purl.obolibrary.org/obo/GO_0051919 GO:0051917 biolink:BiologicalProcess regulation of fibrinolysis Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. go-plus.json http://purl.obolibrary.org/obo/GO_0051917 GO:0051918 biolink:BiologicalProcess negative regulation of fibrinolysis Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. go-plus.json down-regulation of fibrinolysis|downregulation of fibrinolysis|down regulation of fibrinolysis|inhibition of fibrinolysis http://purl.obolibrary.org/obo/GO_0051918 GO:2000184 biolink:BiologicalProcess positive regulation of progesterone biosynthetic process Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. go-plus.json positive regulation of progesterone synthesis|positive regulation of progesterone formation|positive regulation of progesterone biosynthesis|positive regulation of progesterone anabolism http://purl.obolibrary.org/obo/GO_2000184 GO:2000185 biolink:BiologicalProcess regulation of phosphate transmembrane transport Any process that modulates the frequency, rate or extent of phosphate transmembrane transport. go-plus.json regulation of phosphate membrane transport http://purl.obolibrary.org/obo/GO_2000185 GO:2000186 biolink:BiologicalProcess negative regulation of phosphate transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport. go-plus.json negative regulation of phosphate membrane transport http://purl.obolibrary.org/obo/GO_2000186 CHEBI:61278 biolink:ChemicalSubstance scutellarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61278 GO:2000187 biolink:BiologicalProcess positive regulation of phosphate transmembrane transport Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport. go-plus.json positive regulation of phosphate membrane transport http://purl.obolibrary.org/obo/GO_2000187 GO:2000188 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000188 GO:2000189 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000189 GO:2000180 biolink:BiologicalProcess negative regulation of androgen biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process. go-plus.json negative regulation of androgen biosynthesis|negative regulation of androgen anabolism|negative regulation of androgen synthesis|negative regulation of androgen formation http://purl.obolibrary.org/obo/GO_2000180 GO:2000181 biolink:BiologicalProcess negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000181 CHEBI:26948 biolink:ChemicalSubstance vitamin B1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_26948 GO:2000182 biolink:BiologicalProcess regulation of progesterone biosynthetic process Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. go-plus.json regulation of progesterone anabolism|regulation of progesterone synthesis|regulation of progesterone formation|regulation of progesterone biosynthesis http://purl.obolibrary.org/obo/GO_2000182 GO:2000183 biolink:BiologicalProcess negative regulation of progesterone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. go-plus.json negative regulation of progesterone formation|negative regulation of progesterone anabolism|negative regulation of progesterone biosynthesis|negative regulation of progesterone synthesis http://purl.obolibrary.org/obo/GO_2000183 CHEBI:26955 biolink:ChemicalSubstance thiocyanates go-plus.json http://purl.obolibrary.org/obo/CHEBI_26955 GO:0051922 biolink:MolecularActivity cholesterol sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate. EC:2.8.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0051922 CHEBI:61280 biolink:ChemicalSubstance 5-nitroanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61280 GO:0051923 biolink:BiologicalProcess sulfation The addition of a sulfate group to a molecule. go-plus.json phase II metabolism|sulfur addition|sulphur addition|sulfonation|sulphation http://purl.obolibrary.org/obo/GO_0051923 GO:0051920 biolink:MolecularActivity peroxiredoxin activity Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. Reactome:R-HSA-1500804|MetaCyc:1.11.1.15-RXN|Reactome:R-HSA-1222431|EC:1.11.1.24|RHEA:10008|Reactome:R-HSA-1222755 go-plus.json AhpC activity|thiol-containing-reductant:hydroperoxide oxidoreductase activity|PRDX activity|Prx activity|alkyl hydroperoxide reductase C22 activity http://purl.obolibrary.org/obo/GO_0051920 CHEBI:26952 biolink:ChemicalSubstance thioacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26952 GO:0051921 biolink:MolecularActivity adenosylcobyric acid synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate. EC:6.3.5.10|MetaCyc:R345-RXN|RHEA:23256|KEGG_REACTION:R05225 go-plus.json Ado-cobyric acid synthase [glutamine hydrolyzing] activity|CobQ activity|cobyric acid synthase activity|adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)|5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity|adenosylcobyric acid synthase (glutamine-hydrolysing) activity http://purl.obolibrary.org/obo/GO_0051921 CHEBI:26953 biolink:ChemicalSubstance thioadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26953 GO:0051926 biolink:BiologicalProcess negative regulation of calcium ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down regulation of calcium ion transport|downregulation of calcium ion transport|down-regulation of calcium ion transport|inhibition of calcium ion transport|negative regulation of calcium transport http://purl.obolibrary.org/obo/GO_0051926 CHEBI:61283 biolink:ChemicalSubstance baicalin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61283 chebi_ph7_3 GO:0051927 biolink:BiologicalProcess obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel. go-plus.json inhibition of calcium ion transport via voltage gated calcium channel|negative regulation of calcium ion transport via voltage-gated calcium channel activity|negative regulation of calcium transport via voltage gated calcium channel|down regulation of calcium ion transport via voltage gated calcium channel|downregulation of calcium ion transport via voltage gated calcium channel|down-regulation of calcium ion transport via voltage gated calcium channel http://purl.obolibrary.org/obo/GO_0051927 CHEBI:61284 biolink:ChemicalSubstance scutellarin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61284 chebi_ph7_3 GO:0051924 biolink:BiologicalProcess regulation of calcium ion transport Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of calcium transport http://purl.obolibrary.org/obo/GO_0051924 CHEBI:61281 biolink:ChemicalSubstance 5-nitrosalicylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61281 CHEBI:85230 biolink:ChemicalSubstance N-arachidonoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85230 chebi_ph7_3 GO:0051925 biolink:BiologicalProcess obsolete regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel. go-plus.json regulation of calcium transport via voltage-gated calcium channel|regulation of calcium ion transport via voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0051925 CHEBI:61282 biolink:ChemicalSubstance wogonin 7-O-beta-D-glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61282 CHEBI:85231 biolink:ChemicalSubstance 1-(9Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85231 chebi_ph7_3 CHEBI:85232 biolink:ChemicalSubstance prostaglandin D2 1-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_85232 chebi_ph7_3 CHEBI:61287 biolink:ChemicalSubstance (S)-2-O-sulfonatolactate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61287 chebi_ph7_3 CHEBI:61285 biolink:ChemicalSubstance wogonin 7-O-beta-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61285 chebi_ph7_3 GO:0051928 biolink:BiologicalProcess positive regulation of calcium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of calcium ion transport|activation of calcium ion transport|stimulation of calcium ion transport|positive regulation of calcium transport|up-regulation of calcium ion transport|upregulation of calcium ion transport http://purl.obolibrary.org/obo/GO_0051928 CHEBI:85234 biolink:ChemicalSubstance human blood serum metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_85234 GO:0051929 biolink:BiologicalProcess obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via the activity of voltage-gated calcium channels. go-plus.json up-regulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium ion transport via voltage-gated calcium channel activity|upregulation of calcium ion transport via voltage gated calcium channel|up regulation of calcium ion transport via voltage gated calcium channel|activation of calcium ion transport via voltage gated calcium channel|stimulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium transport via voltage gated calcium channel http://purl.obolibrary.org/obo/GO_0051929 CHEBI:61286 biolink:ChemicalSubstance dolichol-linked oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61286 CHEBI:85236 biolink:ChemicalSubstance 15-deoxy-Delta(12,14)-prostaglandin J2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85236 chebi_ph7_3 GO:2000195 biolink:BiologicalProcess negative regulation of female gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. go-plus.json negative regulation of ovary development|negative regulation of ovarian development http://purl.obolibrary.org/obo/GO_2000195 GO:2000196 biolink:BiologicalProcess positive regulation of female gonad development Any process that activates or increases the frequency, rate or extent of female gonad development. go-plus.json positive regulation of ovary development|positive regulation of ovarian development http://purl.obolibrary.org/obo/GO_2000196 CHEBI:85237 biolink:ChemicalSubstance 1-myristoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85237 GO:2000197 biolink:BiologicalProcess regulation of ribonucleoprotein complex localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. go-plus.json regulation of cellular ribonucleoprotein complex localization|regulation of establishment and maintenance of ribonucleoprotein complex localization|regulation of ribonucleoprotein complex localisation|regulation of RNP localization http://purl.obolibrary.org/obo/GO_2000197 CHEBI:85238 biolink:ChemicalSubstance 15-deoxy-Delta(12,14)-prostaglandin J2-2-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_85238 chebi_ph7_3 CHEBI:61289 biolink:ChemicalSubstance (S)-3-sulfonatolactate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61289 chebi_ph7_3 GO:2000198 biolink:BiologicalProcess negative regulation of ribonucleoprotein complex localization Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization. go-plus.json negative regulation of ribonucleoprotein complex localisation|negative regulation of RNP localization|negative regulation of cellular ribonucleoprotein complex localization|negative regulation of establishment and maintenance of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000198 GO:2000199 biolink:BiologicalProcess positive regulation of ribonucleoprotein complex localization Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization. go-plus.json positive regulation of cellular ribonucleoprotein complex localization|positive regulation of RNP localization|positive regulation of ribonucleoprotein complex localisation|positive regulation of establishment and maintenance of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000199 GO:2000190 biolink:BiologicalProcess obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor. go-plus.json negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor http://purl.obolibrary.org/obo/GO_2000190 GO:2000191 biolink:BiologicalProcess regulation of fatty acid transport Any process that modulates the frequency, rate or extent of fatty acid transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000191 GO:2000192 biolink:BiologicalProcess negative regulation of fatty acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000192 CHEBI:26959 biolink:ChemicalSubstance thiocarboxylic ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_26959 GO:2000193 biolink:BiologicalProcess positive regulation of fatty acid transport Any process that activates or increases the frequency, rate or extent of fatty acid transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000193 GO:2000194 biolink:BiologicalProcess regulation of female gonad development Any process that modulates the frequency, rate or extent of female gonad development. go-plus.json regulation of ovary development|regulation of ovarian development http://purl.obolibrary.org/obo/GO_2000194 CHEBI:26921 biolink:ChemicalSubstance tetrahydropyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26921 GO:0051930 biolink:BiologicalProcess regulation of sensory perception of pain Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. go-plus.json http://purl.obolibrary.org/obo/GO_0051930 GO:0051933 biolink:BiologicalProcess amino acid neurotransmitter reuptake The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go-plus.json amino acid uptake during transmission of nerve impulse|amino acid neurotransmitter import into neuron|amino acid neurotransmitter import into glial cell|amino acid neurotransmitter recycling http://purl.obolibrary.org/obo/GO_0051933 GO:0051934 biolink:BiologicalProcess catecholamine uptake involved in synaptic transmission The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go-plus.json catecholamine neurotransmitter recycling|catecholamine neurotransmitter import into neuron|catecholamine neurotransmitter import into glial cell|catecholamine neurotransmitter reuptake|catecholamine reuptake during transmission of nerve impulse|catecholamine uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051934 CHEBI:61291 biolink:ChemicalSubstance (R)-4-phosphopantoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61291 GO:0051931 biolink:BiologicalProcess regulation of sensory perception Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. go-plus.json http://purl.obolibrary.org/obo/GO_0051931 GO:0051932 biolink:BiologicalProcess synaptic transmission, GABAergic The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json synaptic transmission, GABA mediated|synaptic transmission, gamma-aminobutyric acid mediated|GABAergic synaptic transmission|synaptic transmission, gamma-aminobutyric acid-ergic http://purl.obolibrary.org/obo/GO_0051932 CHEBI:26920 biolink:ChemicalSubstance tetrahydropteroyltri-L-glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26920 CHEBI:85261 biolink:ChemicalSubstance N-dodecanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85261 chebi_ph7_3 GO:0051937 biolink:BiologicalProcess catecholamine transport The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_0051937 CHEBI:61294 biolink:ChemicalSubstance (R)-4-phosphonatopantoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61294 chebi_ph7_3 CHEBI:85262 biolink:ChemicalSubstance N-(tetradecanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85262 chebi_ph7_3 GO:0051938 biolink:BiologicalProcess L-glutamate import The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. go-plus.json L-glutamate uptake http://purl.obolibrary.org/obo/GO_0051938 CHEBI:61295 biolink:ChemicalSubstance guanyl ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61295 GO:0051935 biolink:BiologicalProcess glutamate reuptake The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go-plus.json glutamate uptake during transmission of nerve impulse|L-glutamate reuptake|L-glutamate uptake during transmission of nerve impulse|L-glutamate uptake involved in synaptic transmission|glutamate recycling|glutamate import into glial cell|glutamate import into neuron http://purl.obolibrary.org/obo/GO_0051935 CHEBI:85263 biolink:ChemicalSubstance N-(dodecanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85263 chebi_ph7_3 CHEBI:61292 biolink:ChemicalSubstance guanyl nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61292 CHEBI:61293 biolink:ChemicalSubstance adenyl nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61293 GO:0051936 biolink:BiologicalProcess gamma-aminobutyric acid reuptake The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go-plus.json gamma-aminobutyric acid uptake during transmission of nerve impulse|gamma-aminobutyric acid uptake involved in synaptic transmission|gamma-aminobutyric acid recycling|GABA import into neuron|GABA import into glial cell|GABA recycling|gamma-aminobutyric acid import into neuron|GABA reuptake|gamma-aminobutyric acid import into glial cell http://purl.obolibrary.org/obo/GO_0051936 CHEBI:61298 biolink:ChemicalSubstance D-glucose- and/or D-galactose-substituted mannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_61298 GO:0051939 biolink:BiologicalProcess gamma-aminobutyric acid import The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. go-plus.json gamma-aminobutyrate import|gamma-aminobutyric acid uptake|GABA import|4-aminobutyrate import http://purl.obolibrary.org/obo/GO_0051939 CHEBI:61296 biolink:ChemicalSubstance adenyl ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61296 CHEBI:85268 biolink:ChemicalSubstance (5Z)-icosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85268 chebi_ph7_3 CHEBI:61297 biolink:ChemicalSubstance adenyl deoxyribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61297 CHEBI:26925 biolink:ChemicalSubstance naphthalenetetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26925 GO:0051940 biolink:BiologicalProcess regulation of catecholamine uptake involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. go-plus.json regulation of catecholamine uptake during transmission of nerve impulse|regulation of catecholamine neurotransmitter uptake|regulation of catecholamine neurotransmitter reuptake http://purl.obolibrary.org/obo/GO_0051940 CHEBI:26932 biolink:ChemicalSubstance tetrapyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_26932 CHEBI:26933 biolink:ChemicalSubstance tetraric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26933 GO:0051941 biolink:BiologicalProcess regulation of amino acid uptake involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. go-plus.json regulation of amino acid neurotransmitter uptake|regulation of amino acid neurotransmitter reuptake|regulation of amino acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051941 CHEBI:26935 biolink:ChemicalSubstance tetraterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26935 GO:0051944 biolink:BiologicalProcess positive regulation of catecholamine uptake involved in synaptic transmission Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. go-plus.json positive regulation of catecholamine neurotransmitter reuptake|upregulation of catecholamine uptake during transmission of nerve impulse|up regulation of catecholamine uptake during transmission of nerve impulse|activation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine uptake during transmission of nerve impulse|stimulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter uptake|up-regulation of catecholamine uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051944 GO:0051945 biolink:BiologicalProcess negative regulation of catecholamine uptake involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. go-plus.json negative regulation of catecholamine neurotransmitter reuptake|down regulation of catecholamine uptake during transmission of nerve impulse|downregulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine uptake during transmission of nerve impulse|down-regulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine neurotransmitter uptake|inhibition of catecholamine uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051945 GO:0051942 biolink:BiologicalProcess negative regulation of amino acid uptake involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. go-plus.json downregulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter reuptake|down regulation of amino acid uptake during transmission of nerve impulse|inhibition of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter uptake|down-regulation of amino acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051942 GO:0051943 biolink:BiologicalProcess positive regulation of amino acid uptake involved in synaptic transmission Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. go-plus.json positive regulation of amino acid neurotransmitter uptake|up regulation of amino acid uptake during transmission of nerve impulse|upregulation of amino acid uptake during transmission of nerve impulse|positive regulation of amino acid neurotransmitter reuptake|stimulation of amino acid uptake during transmission of nerve impulse|up-regulation of amino acid uptake during transmission of nerve impulse|activation of amino acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051943 GO:0051948 biolink:BiologicalProcess negative regulation of glutamate uptake involved in transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. go-plus.json down regulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake involved in conduction of nerve impulse|downregulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake during transmission of nerve impulse|down-regulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate reuptake|inhibition of glutamate uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051948 CHEBI:85250 biolink:ChemicalSubstance N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85250 chebi_ph7_3 GO:0051949 biolink:BiologicalProcess negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. go-plus.json negative regulation of GABA uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of GABA reuptake|downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of 4-aminobutyrate reuptake|down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid reuptake|negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse|inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051949 GO:0051946 biolink:BiologicalProcess regulation of glutamate uptake involved in transmission of nerve impulse Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. go-plus.json regulation of glutamate uptake during transmission of nerve impulse|regulation of L-glutamate reuptake|regulation of glutamate reuptake|regulation of L-glutamate uptake during transmission of nerve impulse|regulation of glutamate uptake involved in conduction of nerve impulse http://purl.obolibrary.org/obo/GO_0051946 CHEBI:85252 biolink:ChemicalSubstance N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85252 chebi_ph7_3 GO:0051947 biolink:BiologicalProcess regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. go-plus.json regulation of GABA reuptake|regulation of gamma-aminobutyric acid reuptake|regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|regulation of GABA uptake during transmission of nerve impulse|regulation of 4-aminobutyrate uptake during transmission of nerve impulse|regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|regulation of 4-aminobutyrate reuptake http://purl.obolibrary.org/obo/GO_0051947 CHEBI:85253 biolink:ChemicalSubstance N-(icosanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85253 chebi_ph7_3 CHEBI:26936 biolink:ChemicalSubstance tetrathionate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_26936 CHEBI:26937 biolink:ChemicalSubstance monoatomic tetracation go-plus.json http://purl.obolibrary.org/obo/CHEBI_26937 chebi_ph7_3 CHEBI:26938 biolink:ChemicalSubstance tetrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_26938 GO:0051951 biolink:BiologicalProcess positive regulation of glutamate uptake involved in transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. go-plus.json up-regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate reuptake|upregulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake involved in conduction of nerve impulse|up regulation of glutamate uptake during transmission of nerve impulse|activation of glutamate uptake during transmission of nerve impulse|stimulation of glutamate uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051951 CL:0013000 biolink:Cell forebrain radial glial cell go-plus.json http://purl.obolibrary.org/obo/CL_0013000 GO:0051952 biolink:BiologicalProcess regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051952 CHEBI:26900 biolink:ChemicalSubstance tetradecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_26900 CHEBI:26901 biolink:ChemicalSubstance benzyltetrahydroisoquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_26901 GO:0051950 biolink:BiologicalProcess positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. go-plus.json positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse|positive regulation of 4-aminobutyrate reuptake|positive regulation of gamma-aminobutyric acid reuptake|up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of GABA uptake during transmission of nerve impulse|positive regulation of GABA reuptake|positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|activation of gamma-aminobutyric acid uptake during transmission of nerve impulse|stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051950 GO:0051955 biolink:BiologicalProcess regulation of amino acid transport Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051955 GO:0051956 biolink:BiologicalProcess negative regulation of amino acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down-regulation of amino acid transport|negative regulation of amino acid transmembrane transport|downregulation of amino acid transport|down regulation of amino acid transport|inhibition of amino acid transport http://purl.obolibrary.org/obo/GO_0051956 CHEBI:85280 biolink:ChemicalSubstance S-3-[(2R)-phycocyanobilin]-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85280 chebi_ph7_3 CHEBI:85281 biolink:ChemicalSubstance N-(polyunsaturated fatty acyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85281 chebi_ph7_3 GO:0051953 biolink:BiologicalProcess negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down regulation of amine transport|downregulation of amine transport|down-regulation of amine transport|inhibition of amine transport http://purl.obolibrary.org/obo/GO_0051953 CHEBI:85282 biolink:ChemicalSubstance N-(monounsaturated fatty acyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85282 chebi_ph7_3 GO:0051954 biolink:BiologicalProcess positive regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json upregulation of amine transport|up regulation of amine transport|activation of amine transport|stimulation of amine transport|up-regulation of amine transport http://purl.obolibrary.org/obo/GO_0051954 GO:0051959 biolink:MolecularActivity dynein light intermediate chain binding Binding to a light intermediate chain of the dynein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0051959 CHEBI:85283 biolink:ChemicalSubstance N-(saturated fatty acyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85283 chebi_ph7_3 GO:2000148 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in ventricular septum morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000148 CHEBI:85284 biolink:ChemicalSubstance N-(11Z)-icosenoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85284 chebi_ph7_3 GO:2000149 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000149 GO:0051957 biolink:BiologicalProcess positive regulation of amino acid transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json upregulation of amino acid transport|stimulation of amino acid transport|up-regulation of amino acid transport|activation of amino acid transport|up regulation of amino acid transport|positive regulation of amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0051957 CHEBI:85285 biolink:ChemicalSubstance N-(11Z)-icosenoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85285 chebi_ph7_3 CHEBI:85286 biolink:ChemicalSubstance N-(11Z)-icosenoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85286 chebi_ph7_3 GO:0051958 biolink:BiologicalProcess methotrexate transport The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase. go-plus.json http://purl.obolibrary.org/obo/GO_0051958 CHEBI:85288 biolink:ChemicalSubstance S-3-[(2R)-phycoviolobilin]-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85288 chebi_ph7_3 GO:2000140 biolink:BiologicalProcess negative regulation of octopamine signaling pathway involved in response to food Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food. go-plus.json negative regulation of octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_2000140 GO:0036398 biolink:CellularComponent TCR signalosome A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology. go-plus.json LAT signalosome|linker for activation of T cells signalosome http://purl.obolibrary.org/obo/GO_0036398 GO:0036399 biolink:BiologicalProcess TCR signalosome assembly The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome. go-plus.json linker for activation of T cells signalosome assembly|LAT signalosome assembly http://purl.obolibrary.org/obo/GO_0036399 GO:2000141 biolink:BiologicalProcess positive regulation of octopamine signaling pathway involved in response to food Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food. go-plus.json positive regulation of octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_2000141 GO:2000142 biolink:BiologicalProcess regulation of DNA-templated transcription, initiation Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation. go-plus.json regulation of DNA-dependent transcription, initiation|regulation of initiation of DNA-dependent transcription|regulation of transcription initiation, DNA-dependent http://purl.obolibrary.org/obo/GO_2000142 GO:2000143 biolink:BiologicalProcess negative regulation of DNA-templated transcription, initiation Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation. go-plus.json negative regulation of DNA-dependent transcription, initiation|negative regulation of initiation of DNA-dependent transcription|negative regulation of transcription initiation, DNA-dependent http://purl.obolibrary.org/obo/GO_2000143 GO:2000144 biolink:BiologicalProcess positive regulation of DNA-templated transcription, initiation Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation. go-plus.json positive regulation of DNA-dependent transcription, initiation|transcriptional transactivation|positive regulation of initiation of DNA-dependent transcription|positive regulation of transcription initiation, DNA-dependent|transactivation http://purl.obolibrary.org/obo/GO_2000144 GO:2000145 biolink:BiologicalProcess regulation of cell motility Any process that modulates the frequency, rate or extent of cell motility. go-plus.json regulation of cell movement|regulation of cell locomotion|regulation of movement of a cell http://purl.obolibrary.org/obo/GO_2000145 GO:2000146 biolink:BiologicalProcess negative regulation of cell motility Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. go-plus.json negative regulation of cell locomotion|negative regulation of movement of a cell|negative regulation of cell movement http://purl.obolibrary.org/obo/GO_2000146 GO:2000147 biolink:BiologicalProcess positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of cell motility. go-plus.json positive regulation of movement of a cell|positive regulation of cell movement|positive regulation of cell locomotion http://purl.obolibrary.org/obo/GO_2000147 GO:0036390 biolink:BiologicalProcess pre-replicative complex assembly involved in bacterial-type DNA replication The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go-plus.json bacterial pre-RC assembly|bacterial pre-replicative complex assembly http://purl.obolibrary.org/obo/GO_0036390 CHEBI:26907 biolink:ChemicalSubstance tetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26907 GO:0036391 biolink:CellularComponent medial cortex septin ring A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0036391 CHEBI:26908 biolink:ChemicalSubstance tetrahydrofolyl glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26908 GO:0036392 biolink:BiologicalProcess chemokine (C-C motif) ligand 20 production The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CCL-20 production|C-C motif chemokine 20 production|CCL20 production http://purl.obolibrary.org/obo/GO_0036392 gocheck_do_not_annotate GO:0036393 biolink:MolecularActivity thiocyanate peroxidase activity Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate. go-plus.json lactoperoxidase activity http://purl.obolibrary.org/obo/GO_0036393 GO:0036394 biolink:BiologicalProcess amylase secretion The controlled release of amylase from a cell. go-plus.json amylase release http://purl.obolibrary.org/obo/GO_0036394 GO:0036395 biolink:BiologicalProcess pancreatic amylase secretion The controlled release of amylase from a cell of the pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_0036395 CHEBI:26904 biolink:ChemicalSubstance tetrahydrocorphin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26904 GO:0036396 biolink:CellularComponent RNA N6-methyladenosine methyltransferase complex A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). go-plus.json m6A methyltransferase complex|m(6)A writer complex|WMM complex|METTL3-METTL14-WTAP methyltransferase complex|MIS complex|Mum2, Ime4, and Slz1 complex http://purl.obolibrary.org/obo/GO_0036396 GO:0036397 biolink:MolecularActivity formate dehydrogenase (quinone) activity Catalysis of the reaction: formate + a quinone = CO2 + a quinol. EC:1.17.5.3|RHEA:48592|KEGG_REACTION:R09494|MetaCyc:FORMATEDEHYDROG-RXN go-plus.json formate:quinone oxidoreductase activity|Fdh-N activity|formate dehydrogenase-N activity http://purl.obolibrary.org/obo/GO_0036397 GO:0051962 biolink:BiologicalProcess positive regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. go-plus.json stimulation of nervous system development|up-regulation of nervous system development|activation of nervous system development|up regulation of nervous system development|upregulation of nervous system development http://purl.obolibrary.org/obo/GO_0051962 NCBITaxon:10066 biolink:OrganismalEntity Muridae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_10066 CHEBI:26911 biolink:ChemicalSubstance oxolane go-plus.json http://purl.obolibrary.org/obo/CHEBI_26911 chebi_ph7_3 GO:0051963 biolink:BiologicalProcess regulation of synapse assembly Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. go-plus.json regulation of synapse biogenesis|regulation of synaptogenesis http://purl.obolibrary.org/obo/GO_0051963 goslim_synapse CHEBI:26912 biolink:ChemicalSubstance oxolanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_26912 GO:0051960 biolink:BiologicalProcess regulation of nervous system development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0051960 GO:0051961 biolink:BiologicalProcess negative regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. go-plus.json down-regulation of nervous system development|downregulation of nervous system development|down regulation of nervous system development|inhibition of nervous system development http://purl.obolibrary.org/obo/GO_0051961 GO:0051966 biolink:BiologicalProcess regulation of synaptic transmission, glutamatergic Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0051966 GO:0051967 biolink:BiologicalProcess negative regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. go-plus.json downregulation of synaptic transmission, glutamatergic|down regulation of synaptic transmission, glutamatergic|inhibition of synaptic transmission, glutamatergic|down-regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051967 CHEBI:85270 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85270 chebi_ph7_3 GO:0051964 biolink:BiologicalProcess negative regulation of synapse assembly Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. go-plus.json down-regulation of synapse assembly|negative regulation of synapse biogenesis|negative regulation of synaptogenesis|downregulation of synapse assembly|down regulation of synapse assembly|inhibition of synapse assembly http://purl.obolibrary.org/obo/GO_0051964 GO:0051965 biolink:BiologicalProcess positive regulation of synapse assembly Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. go-plus.json stimulation of synapse assembly|up-regulation of synapse assembly|activation of synapse assembly|up regulation of synapse assembly|positive regulation of synapse biogenesis|positive regulation of synaptogenesis|upregulation of synapse assembly http://purl.obolibrary.org/obo/GO_0051965 CHEBI:85271 biolink:ChemicalSubstance (Kdo)2-lipid A 1-diphosphate(7-) (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85271 chebi_ph7_3 GO:0120307 biolink:CellularComponent Hechtian strand An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely. Wikipedia:Hechtian_strand go-plus.json http://purl.obolibrary.org/obo/GO_0120307 GO:2000159 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in heart morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000159 GO:0120308 biolink:BiologicalProcess axonemal outer doublet assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule. go-plus.json axonemal outer doublet morphogenesis|axoneme outer doublet assembly|outer doublet assembly|outer-doublet microtubule assembly|axonemal outer doublet biogenesis|axonemal outer doublet formation http://purl.obolibrary.org/obo/GO_0120308 GO:0120309 biolink:BiologicalProcess cilium attachment to cell body A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species. go-plus.json flagellar attachment to cell body|ciliary attachment to cell body|flagellum attachment to cell body|cilial attachment to cell body http://purl.obolibrary.org/obo/GO_0120309 GO:0051968 biolink:BiologicalProcess positive regulation of synaptic transmission, glutamatergic Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. go-plus.json upregulation of synaptic transmission, glutamatergic|stimulation of synaptic transmission, glutamatergic|activation of synaptic transmission, glutamatergic|up-regulation of synaptic transmission, glutamatergic|up regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051968 GO:0051969 biolink:BiologicalProcess regulation of transmission of nerve impulse Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. go-plus.json regulation of conduction of nerve impulse http://purl.obolibrary.org/obo/GO_0051969 CHEBI:85275 biolink:ChemicalSubstance (3E)-phycocyanobilin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85275 chebi_ph7_3 GO:0120303 biolink:BiologicalProcess visually-mediated background adaptation Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells. go-plus.json http://purl.obolibrary.org/obo/GO_0120303 CHEBI:85276 biolink:ChemicalSubstance (3E)-phycoerythrobilin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85276 chebi_ph7_3 GO:0120304 biolink:BiologicalProcess integument-mediated background adaptation Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument. go-plus.json http://purl.obolibrary.org/obo/GO_0120304 CHEBI:85277 biolink:ChemicalSubstance N-arachidonoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85277 chebi_ph7_3 GO:0120305 biolink:BiologicalProcess regulation of pigmentation Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0120305 CHEBI:85278 biolink:ChemicalSubstance 17beta-hydroxyandrostan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85278 chebi_ph7_3 GO:0120306 biolink:BiologicalProcess cellular response to actin cytoskeletal stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton. go-plus.json cellular response to actin cytoskeleton stress|response to latrunculin B|response to latrunculin A|cellular response to latrunculin B|cellular response to latrunculin A http://purl.obolibrary.org/obo/GO_0120306 CHEBI:85279 biolink:ChemicalSubstance S-3-[(2R)-phycoerythrobilin]-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85279 chebi_ph7_3 GO:0036387 biolink:CellularComponent pre-replicative complex A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go-plus.json pre-RC|pre-replication complex http://purl.obolibrary.org/obo/GO_0036387 GO:2000151 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000151 GO:0036388 biolink:BiologicalProcess pre-replicative complex assembly The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go-plus.json pre-replication complex assembly|pre-RC assembly http://purl.obolibrary.org/obo/GO_0036388 GO:2000152 biolink:BiologicalProcess regulation of ubiquitin-specific protease activity Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity. go-plus.json regulation of UBP|regulation of UCH2|regulation of deubiquitinase activity http://purl.obolibrary.org/obo/GO_2000152 GO:0120300 biolink:MolecularActivity peptide lactyltransferase activity Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein]. RHEA:61996 go-plus.json http://purl.obolibrary.org/obo/GO_0120300 GO:0036389 biolink:CellularComponent bacterial pre-replicative complex A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. go-plus.json bacterial pre-RC http://purl.obolibrary.org/obo/GO_0036389 GO:0120301 biolink:MolecularActivity histone lactyltransferase activity Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[histone]. go-plus.json http://purl.obolibrary.org/obo/GO_0120301 GO:2000153 biolink:BiologicalProcess obsolete regulation of flagellar cell motility OBSOLETE. Any process that modulates the frequency, rate or extent of flagellar cell motility. go-plus.json regulation of flagellar cell motility http://purl.obolibrary.org/obo/GO_2000153 GO:2000154 biolink:BiologicalProcess obsolete negative regulation of flagellar cell motility OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of flagellar cell motility. go-plus.json negative regulation of flagellar cell motility http://purl.obolibrary.org/obo/GO_2000154 GO:0120302 biolink:BiologicalProcess background adaptation Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity. go-plus.json http://purl.obolibrary.org/obo/GO_0120302 GO:2000155 biolink:BiologicalProcess positive regulation of cilium-dependent cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. go-plus.json positive regulation of ciliary cell motility http://purl.obolibrary.org/obo/GO_2000155 GO:2000156 biolink:BiologicalProcess regulation of retrograde vesicle-mediated transport, Golgi to ER Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER. go-plus.json regulation of retrograde transport, Golgi to ER|regulation of retrograde (Golgi to ER) transport|regulation of retrograde transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough ER vesicle-mediated transport|regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|regulation of cis-Golgi to rough endoplasmic reticulum transport|regulation of cis-Golgi to rough ER transport|regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum http://purl.obolibrary.org/obo/GO_2000156 GO:2000157 biolink:BiologicalProcess negative regulation of ubiquitin-specific protease activity Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. go-plus.json negative regulation of UCH2|negative regulation of deubiquitinase activity|negative regulation of ubiquitin hydrolase activity|negative regulation of UBP http://purl.obolibrary.org/obo/GO_2000157 GO:2000158 biolink:BiologicalProcess positive regulation of ubiquitin-specific protease activity Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. go-plus.json positive regulation of deubiquitinase activity|positive regulation of UCH2|positive regulation of UBP|positive regulation of ubiquitin hydrolase activity http://purl.obolibrary.org/obo/GO_2000158 GO:0036380 biolink:MolecularActivity UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. RHEA:28090|MetaCyc:GLCNACPTRANS-RXN|KEGG_REACTION:R08856|EC:2.7.8.33 go-plus.json UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|GlcNAc-P-P-Und synthase activity|UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity|UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity http://purl.obolibrary.org/obo/GO_0036380 GO:0036381 biolink:MolecularActivity pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate. MetaCyc:RXN-11322|RHEA:31507|KEGG_REACTION:R10089|EC:4.3.3.6 go-plus.json PdxST activity|pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity http://purl.obolibrary.org/obo/GO_0036381 GO:0036382 biolink:MolecularActivity flavin reductase (NADH) activity Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+. EC:1.5.1.36|RHEA:31303|MetaCyc:1.5.1.36-RXN|KEGG_REACTION:R09662 go-plus.json NADH-dependent flavin reductase activity|flavin:NADH oxidoreductase activity http://purl.obolibrary.org/obo/GO_0036382 CHEBI:26914 biolink:ChemicalSubstance tetrahydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26914 GO:0036383 biolink:MolecularActivity 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O. EC:1.14.14.12|KEGG_REACTION:R09819|RHEA:31731|MetaCyc:1.14.14.12-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0036383 GO:0036384 biolink:MolecularActivity cytidine-diphosphatase activity Catalysis of the reaction: CDP + H2O = CMP + phosphate. RHEA:64880 go-plus.json CDPase activity http://purl.obolibrary.org/obo/GO_0036384 GO:0036385 biolink:BiologicalProcess nucleoid DNA packaging Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid. go-plus.json http://purl.obolibrary.org/obo/GO_0036385 CHEBI:26916 biolink:ChemicalSubstance tetrahydronicotinamide adenine dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26916 GO:2000150 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000150 GO:0036386 biolink:BiologicalProcess bacterial nucleoid DNA packaging Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling. go-plus.json prokaryotic DNA condensation|nucleoid compaction|chromosomal compaction http://purl.obolibrary.org/obo/GO_0036386 GO:0051973 biolink:BiologicalProcess positive regulation of telomerase activity Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). go-plus.json up regulation of telomerase activity|activation of telomerase activity|stimulation of telomerase activity|telomerase activator|up-regulation of telomerase activity|upregulation of telomerase activity http://purl.obolibrary.org/obo/GO_0051973 GO:0051974 biolink:BiologicalProcess negative regulation of telomerase activity Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). go-plus.json telomerase inhibitor|down regulation of telomerase activity|downregulation of telomerase activity|down-regulation of telomerase activity|inhibition of telomerase activity http://purl.obolibrary.org/obo/GO_0051974 GO:0051971 biolink:BiologicalProcess positive regulation of transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. go-plus.json up-regulation of transmission of nerve impulse|positive regulation of conduction of nerve impulse|upregulation of transmission of nerve impulse|up regulation of transmission of nerve impulse|activation of transmission of nerve impulse|stimulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051971 GO:0051972 biolink:BiologicalProcess regulation of telomerase activity Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. go-plus.json telomerase regulator http://purl.obolibrary.org/obo/GO_0051972 GO:0051977 biolink:BiologicalProcess lysophospholipid transport The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. go-plus.json http://purl.obolibrary.org/obo/GO_0051977 GO:0051978 biolink:MolecularActivity lysophospholipid:sodium symporter activity Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. go-plus.json lysophospholipid transporter activity http://purl.obolibrary.org/obo/GO_0051978 GO:0051975 biolink:BiologicalProcess lysine biosynthetic process via alpha-aminoadipate and saccharopine The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine. MetaCyc:LYSINE-AMINOAD-PWY go-plus.json lysine biosynthetic process via aminoadipic acid and saccharopine|lysine biosynthesis via aminoadipic acid and saccharopine http://purl.obolibrary.org/obo/GO_0051975 GO:0051976 biolink:BiologicalProcess lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine. MetaCyc:PWY-3081 go-plus.json lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate|lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate http://purl.obolibrary.org/obo/GO_0051976 GO:0120318 biolink:BiologicalProcess olfactory sociosexual communication The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system. go-plus.json http://purl.obolibrary.org/obo/GO_0120318 GO:0120319 biolink:MolecularActivity long-chain fatty acid omega-1 hydroxylase activity Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. RHEA:60936 go-plus.json cytochrome P450 fatty acid omega-1 hydroxylase activity http://purl.obolibrary.org/obo/GO_0120319 GO:0051979 biolink:BiologicalProcess alginic acid acetylation The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate. go-plus.json alginate acetylation http://purl.obolibrary.org/obo/GO_0051979 GO:0120314 biolink:BiologicalProcess negative regulation of oocyte karyosome formation Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go-plus.json http://purl.obolibrary.org/obo/GO_0120314 GO:0120315 biolink:BiologicalProcess positive regulation of oocyte karyosome formation Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go-plus.json http://purl.obolibrary.org/obo/GO_0120315 GO:0120316 biolink:BiologicalProcess sperm flagellum assembly The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium). go-plus.json http://purl.obolibrary.org/obo/GO_0120316 GO:0120317 biolink:BiologicalProcess sperm mitochondrial sheath assembly The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum. go-plus.json http://purl.obolibrary.org/obo/GO_0120317 GO:0036376 biolink:BiologicalProcess sodium ion export across plasma membrane The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json sodium export|sodium ion export|sodium ion export from cell http://purl.obolibrary.org/obo/GO_0036376 GO:2000162 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000162 GO:0120310 biolink:BiologicalProcess amastigogenesis The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites. go-plus.json http://purl.obolibrary.org/obo/GO_0120310 GO:0036377 biolink:BiologicalProcess arbuscular mycorrhizal association A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil. go-plus.json arbuscular mycorrhizas formation|arbuscular mycorrhizal symbiosis|arbuscular mycorrhizae formation http://purl.obolibrary.org/obo/GO_0036377 GO:0061300 biolink:BiologicalProcess cerebellum vasculature development The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061300 GO:0120311 biolink:BiologicalProcess ciliary pro-basal body maturation A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium. go-plus.json flagellar pro-basal body maturation|flagellar probasal body maturation|pro-basal body maturation http://purl.obolibrary.org/obo/GO_0120311 GO:2000163 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in outflow tract morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000163 GO:0061301 biolink:BiologicalProcess cerebellum vasculature morphogenesis The process in which the vasculature of the cerebellum is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061301 GO:0036378 biolink:BiologicalProcess calcitriol biosynthetic process from calciol Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. go-plus.json calcitriol biosynthesis from calciol|vitamin D3 activation|1alpha,25(OH)2D3 biosynthesis|1alpha,25-dihydroxyvitamin D3 biosynthesis|1alpha,25-dihydroxycholecalciferol biosynthesis http://purl.obolibrary.org/obo/GO_0036378 GO:0120312 biolink:BiologicalProcess ciliary basal body segregation The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites. go-plus.json microtubule basal body separation|ciliary basal body separation|microtubule basal body segregation http://purl.obolibrary.org/obo/GO_0120312 GO:2000164 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000164 GO:0120313 biolink:BiologicalProcess regulation of oocyte karyosome formation Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go-plus.json http://purl.obolibrary.org/obo/GO_0120313 GO:0061302 biolink:BiologicalProcess smooth muscle cell-matrix adhesion The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0061302 GO:2000165 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in pericardium morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000165 GO:0036379 biolink:CellularComponent myofilament Any of the smallest contractile units of a myofibril (striated muscle fiber). go-plus.json striated muscle filament http://purl.obolibrary.org/obo/GO_0036379 GO:0061303 biolink:BiologicalProcess cornea development in camera-type eye The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. go-plus.json http://purl.obolibrary.org/obo/GO_0061303 GO:2000166 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in pericardium morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000166 GO:2000167 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in neural tube closure Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. go-plus.json http://purl.obolibrary.org/obo/GO_2000167 GO:0061304 biolink:BiologicalProcess retinal blood vessel morphogenesis The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061304 GO:0061305 biolink:BiologicalProcess maintenance of bipolar cell polarity regulating cell shape The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061305 GO:2000168 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in neural tube closure Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. go-plus.json http://purl.obolibrary.org/obo/GO_2000168 GO:0061306 biolink:BiologicalProcess obsolete DNA strand renaturation involved in double-strand break repair OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair. go-plus.json http://purl.obolibrary.org/obo/GO_0061306 GO:2000169 biolink:BiologicalProcess regulation of peptidyl-cysteine S-nitrosylation Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000169 GO:0061307 biolink:BiologicalProcess cardiac neural crest cell differentiation involved in heart development The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. go-plus.json http://purl.obolibrary.org/obo/GO_0061307 GO:0061308 biolink:BiologicalProcess cardiac neural crest cell development involved in heart development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0061308 GO:0061309 biolink:BiologicalProcess cardiac neural crest cell development involved in outflow tract morphogenesis The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. go-plus.json http://purl.obolibrary.org/obo/GO_0061309 GO:0036370 biolink:MolecularActivity D-alanyl carrier activity Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG). go-plus.json D-alanyl carrier protein http://purl.obolibrary.org/obo/GO_0036370 GO:0036371 biolink:BiologicalProcess protein localization to T-tubule A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. go-plus.json protein localization to T tubule|protein localisation to T-tubule|protein localization to transverse tubule http://purl.obolibrary.org/obo/GO_0036371 GO:0036372 biolink:BiologicalProcess opsin transport The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. go-plus.json ciliary transport of opsin http://purl.obolibrary.org/obo/GO_0036372 GO:0051970 biolink:BiologicalProcess negative regulation of transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. go-plus.json inhibition of transmission of nerve impulse|negative regulation of conduction of nerve impulse|down regulation of transmission of nerve impulse|downregulation of transmission of nerve impulse|down-regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0051970 GO:0036373 biolink:MolecularActivity L-fucose mutarotase activity Catalysis of the reaction: alpha-L-fucose = beta-L-fucose. MetaCyc:RXN0-5298|RHEA:25580|EC:5.1.3.29 go-plus.json alpha-L-fucose 1-epimerase activity|fucose 1-epimerase activity|type-2 mutarotase activity http://purl.obolibrary.org/obo/GO_0036373 GO:0036374 biolink:MolecularActivity glutathione hydrolase activity Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. Reactome:R-HSA-5433072|KEGG_REACTION:R00494|Reactome:R-HSA-9035966|Reactome:R-HSA-8943279|MetaCyc:RXN-12618|Reactome:R-HSA-266046|Reactome:R-HSA-9026907|Reactome:R-HSA-9026927|Reactome:R-HSA-9026916|Reactome:R-HSA-5602984|Reactome:R-HSA-9026912|Reactome:R-HSA-9026757|EC:3.4.19.13|RHEA:28807|Reactome:R-HSA-1222712 go-plus.json glutathionase activity|gamma-glutamyltranspeptidase activity http://purl.obolibrary.org/obo/GO_0036374 GO:2000160 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in heart morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000160 GO:0036375 biolink:CellularComponent Kibra-Ex-Mer complex An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2. go-plus.json KEM complex|Kbr, Ex and Mer complex http://purl.obolibrary.org/obo/GO_0036375 GO:2000161 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000161 GO:0051984 biolink:BiologicalProcess positive regulation of chromosome segregation Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. go-plus.json upregulation of chromosome segregation|stimulation of chromosome segregation|up-regulation of chromosome segregation|activation of chromosome segregation|up regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0051984 GO:0051985 biolink:BiologicalProcess negative regulation of chromosome segregation Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. go-plus.json down regulation of chromosome segregation|inhibition of chromosome segregation|down-regulation of chromosome segregation|downregulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0051985 GO:0051982 biolink:MolecularActivity copper-nicotianamine transmembrane transporter activity Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other. go-plus.json Cu-NA chelate transporter activity http://purl.obolibrary.org/obo/GO_0051982 GO:0051983 biolink:BiologicalProcess regulation of chromosome segregation Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. go-plus.json http://purl.obolibrary.org/obo/GO_0051983 GO:0051988 biolink:BiologicalProcess regulation of attachment of spindle microtubules to kinetochore Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. go-plus.json regulation of kinetochore-microtubule attachment http://purl.obolibrary.org/obo/GO_0051988 GO:0051989 biolink:MolecularActivity coproporphyrinogen dehydrogenase activity Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine. EC:1.3.98.3|RHEA:15425|MetaCyc:HEMN-RXN go-plus.json radical SAM enzyme activity|coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)|HemN|oxygen-independent coproporphyrinogen-III oxidase activity|coproporphyrinogen III oxidase activity http://purl.obolibrary.org/obo/GO_0051989 CHEBI:85291 biolink:ChemicalSubstance N,1,2-trioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85291 chebi_ph7_3 GO:0051986 biolink:BiologicalProcess negative regulation of attachment of spindle microtubules to kinetochore Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. go-plus.json downregulation of attachment of spindle microtubules to kinetochore|down-regulation of attachment of spindle microtubules to kinetochore|inhibition of attachment of spindle microtubules to kinetochore|down regulation of attachment of spindle microtubules to kinetochore http://purl.obolibrary.org/obo/GO_0051986 CHEBI:85292 biolink:ChemicalSubstance N-stearoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85292 chebi_ph7_3 GO:0051987 biolink:BiologicalProcess positive regulation of attachment of spindle microtubules to kinetochore Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. go-plus.json up regulation of attachment of spindle microtubules to kinetochore|activation of attachment of spindle microtubules to kinetochore|stimulation of attachment of spindle microtubules to kinetochore|up-regulation of attachment of spindle microtubules to kinetochore|upregulation of attachment of spindle microtubules to kinetochore http://purl.obolibrary.org/obo/GO_0051987 CHEBI:85293 biolink:ChemicalSubstance N-myristoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85293 chebi_ph7_3 CHEBI:85294 biolink:ChemicalSubstance N-lauroyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85294 chebi_ph7_3 CHEBI:85295 biolink:ChemicalSubstance N-capryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85295 chebi_ph7_3 CHEBI:85296 biolink:ChemicalSubstance N-capryloyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85296 chebi_ph7_3 CHEBI:85297 biolink:ChemicalSubstance N-caproyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85297 chebi_ph7_3 GO:0120325 biolink:MolecularActivity NuRD complex binding Binding to a NuRD complex. go-plus.json http://purl.obolibrary.org/obo/GO_0120325 CHEBI:85298 biolink:ChemicalSubstance N-butyryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85298 chebi_ph7_3 GO:0120326 biolink:BiologicalProcess appressorium-mediated entry into host Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json appressorium-mediated invasion into host|appressorium-mediated penetration into host|appressorium-mediated host invasion|appressorium-mediated host penetration http://purl.obolibrary.org/obo/GO_0120326 CHEBI:85299 biolink:ChemicalSubstance N-(octadecanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85299 chebi_ph7_3 GO:0120327 biolink:CellularComponent telopode A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0120327 GO:0120328 biolink:MolecularActivity ATP-dependent DNA (cytosine-5-)-methyltransferase activity Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0120328 GO:2000173 biolink:BiologicalProcess negative regulation of branching morphogenesis of a nerve Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. go-plus.json http://purl.obolibrary.org/obo/GO_2000173 GO:0120321 biolink:CellularComponent nuclear envelope adjacent to nuclear pore complex The region of the nuclear envelope situated in close proximity to a nuclear pore complex. go-plus.json nuclear envelope periphery of the nuclear pore complex|nuclear envelope adjacent to NPC|associated with the nuclear pore http://purl.obolibrary.org/obo/GO_0120321 GO:0036365 biolink:BiologicalProcess transforming growth factor beta2 activation The release of transforming growth factor beta 2 (TGF-beta2) from its latent state. go-plus.json TGF-beta 2 activation|TGFB2 activation|TGFbeta 2 activation http://purl.obolibrary.org/obo/GO_0036365 GO:2000174 biolink:BiologicalProcess regulation of pro-T cell differentiation Any process that modulates the frequency, rate or extent of pro-T cell differentiation. go-plus.json regulation of pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000174 GO:0036366 biolink:BiologicalProcess transforming growth factor beta3 activation The release of transforming growth factor beta 3 (TGF-beta3) from its latent state. go-plus.json TGF-beta 3 activation|TGFB3 activation|TGFbeta 3 activation http://purl.obolibrary.org/obo/GO_0036366 GO:0120322 biolink:BiologicalProcess lipid modification by small protein conjugation A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0120322 GO:2000175 biolink:BiologicalProcess negative regulation of pro-T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation. go-plus.json negative regulation of pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000175 GO:0036367 biolink:BiologicalProcess light adaption The ability of a photoreceptor to adjust to varying levels of light. go-plus.json http://purl.obolibrary.org/obo/GO_0036367 GO:0120323 biolink:BiologicalProcess lipid ubiquitination The process in which one or more ubiquitin groups are added to a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0120323 GO:2000176 biolink:BiologicalProcess positive regulation of pro-T cell differentiation Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation. go-plus.json positive regulation of pro-T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000176 GO:0036368 biolink:BiologicalProcess cone photoresponse recovery The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers. go-plus.json cone phototransduction termination|cone response recovery http://purl.obolibrary.org/obo/GO_0036368 GO:0120324 biolink:BiologicalProcess procyclogenesis The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei. go-plus.json http://purl.obolibrary.org/obo/GO_0120324 GO:0036369 biolink:BiologicalProcess transcription factor catabolic process The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go-plus.json proteasome-mediated transcription factor catabolism|transcription factor catabolism|transcription factor degradation|sequence-specific DNA binding transcription factor catabolic process|transcription factor breakdown http://purl.obolibrary.org/obo/GO_0036369 GO:2000177 biolink:BiologicalProcess regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000177 GO:2000178 biolink:BiologicalProcess negative regulation of neural precursor cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000178 GO:2000179 biolink:BiologicalProcess positive regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000179 GO:0120320 biolink:BiologicalProcess lateral pseudopodium retraction The myosin-based contraction and retraction of a lateral pseudopodium. go-plus.json lateral pseudopodium suppression http://purl.obolibrary.org/obo/GO_0120320 GO:0036360 biolink:BiologicalProcess sorocarp stalk morphogenesis The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum. go-plus.json fruiting body stalk morphogenesis http://purl.obolibrary.org/obo/GO_0036360 GO:0036361 biolink:MolecularActivity racemase activity, acting on amino acids and derivatives Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0036361 GO:0051980 biolink:MolecularActivity iron-nicotianamine transmembrane transporter activity Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other. go-plus.json Fe-NA chelate transporter activity http://purl.obolibrary.org/obo/GO_0051980 GO:2000170 biolink:BiologicalProcess positive regulation of peptidyl-cysteine S-nitrosylation Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000170 GO:0036362 biolink:CellularComponent ascus membrane A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0036362 GO:0051981 biolink:MolecularActivity copper chelate transmembrane transporter activity Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions. go-plus.json http://purl.obolibrary.org/obo/GO_0051981 GO:0036363 biolink:BiologicalProcess transforming growth factor beta activation The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms. go-plus.json L-TGF-beta activation|TGFbeta activation|TGFB activation|latent TGF-beta activation|TGF-B activation|TGF-beta activation http://purl.obolibrary.org/obo/GO_0036363 GO:2000171 biolink:BiologicalProcess negative regulation of dendrite development Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. go-plus.json http://purl.obolibrary.org/obo/GO_2000171 GO:2000172 biolink:BiologicalProcess regulation of branching morphogenesis of a nerve Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. go-plus.json http://purl.obolibrary.org/obo/GO_2000172 GO:0036364 biolink:BiologicalProcess transforming growth factor beta1 activation The release of transforming growth factor beta1 (TGF-beta1) from its latent state. go-plus.json latent-TGF-beta1 activation|TGF-beta 1 activation|TGFB1 activation|L-TGF-beta 1 activation|TGFbeta 1 activation|transforming growth factor-beta1 activation http://purl.obolibrary.org/obo/GO_0036364 CHEBI:75833 biolink:ChemicalSubstance (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75833 CHEBI:51867 biolink:ChemicalSubstance methyl ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51867 CHEBI:75831 biolink:ChemicalSubstance (8E,10S)-10-hydroperoxy-8-octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75831 CHEBI:51869 biolink:ChemicalSubstance alpha-diketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51869 CHEBI:75837 biolink:ChemicalSubstance phytyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75837 CHEBI:75838 biolink:ChemicalSubstance phytyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75838 CHEBI:75835 biolink:ChemicalSubstance anti-anaemic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_75835 GO:0120178 biolink:BiologicalProcess steroid hormone biosynthetic process The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0120178 GO:0120179 biolink:BiologicalProcess adherens junction disassembly The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0120179 CHEBI:36223 biolink:ChemicalSubstance thiomorpholinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36223 GO:0120174 biolink:BiologicalProcess stress-induced homeostatically regulated protein degradation pathway A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway. go-plus.json SHRED pathway http://purl.obolibrary.org/obo/GO_0120174 GO:0120175 biolink:BiologicalProcess regulation of torso signaling pathway Any process that modulates the frequency, rate or extent of the torso signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120175 GO:0120176 biolink:BiologicalProcess positive regulation of torso signaling pathway Any process that activates or increases the frequency, rate or extent of the torso signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120176 GO:0120177 biolink:BiologicalProcess negative regulation of torso signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120177 GO:0120170 biolink:MolecularActivity intraciliary transport particle B binding Binding to an intraciliary transport particle B (IFT B) complex. go-plus.json intraflagellar transport particle B binding|intraflagellar transport complex B binding|IFT B complex binding|intraciliary transport complex B binding http://purl.obolibrary.org/obo/GO_0120170 GO:0120171 biolink:CellularComponent Cdc24p-Far1p-Gbetagamma complex A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit). go-plus.json Cdc24p-Far1p-BG complex|CDC24-FAR1-Gbetagamma complex|CDC24-FAR1-BG complex http://purl.obolibrary.org/obo/GO_0120171 CHEBI:51860 biolink:ChemicalSubstance dexmethylphenidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51860 GO:0120172 biolink:BiologicalProcess positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0120172 GO:0120173 biolink:BiologicalProcess regulation of actin filament bundle convergence involved in mitotic contractile ring assembly Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0120173 CHEBI:75844 biolink:ChemicalSubstance 1,2,3-trilinoleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75844 chebi_ph7_3 CHEBI:75845 biolink:ChemicalSubstance 1,2,3-trilinolenoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75845 chebi_ph7_3 CHEBI:51856 biolink:ChemicalSubstance methylphenidate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_51856 chebi_ph7_3 CHEBI:51857 biolink:ChemicalSubstance methyl (S)-phenyl[(S)-piperidin-2-yl]acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51857 CHEBI:51851 biolink:ChemicalSubstance ketonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_51851 CHEBI:75848 biolink:ChemicalSubstance 1,2-dioleoyl-3-palmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75848 chebi_ph7_3 CHEBI:75849 biolink:ChemicalSubstance 1,3-dipalmitoleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75849 chebi_ph7_3 CHEBI:51852 biolink:ChemicalSubstance alpha-ketonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_51852 CHEBI:75846 biolink:ChemicalSubstance 1,3-dioleoyl-2-palmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75846 chebi_ph7_3 CHEBI:51853 biolink:ChemicalSubstance benzoyl cyanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_51853 chebi_ph7_3 CHEBI:75847 biolink:ChemicalSubstance 1-palmitoyl-2,3-dioleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75847 chebi_ph7_3 CHEBI:61200 biolink:ChemicalSubstance 3-decenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61200 GO:0120189 biolink:BiologicalProcess positive regulation of bile acid secretion Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0120189 CHEBI:36237 biolink:ChemicalSubstance cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36237 CHEBI:61204 biolink:ChemicalSubstance docosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61204 CHEBI:61201 biolink:ChemicalSubstance beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61201 CHEBI:36234 biolink:ChemicalSubstance chenodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36234 chebi_ph7_3 CHEBI:36235 biolink:ChemicalSubstance bile acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36235 GO:0120185 biolink:BiologicalProcess MBF transcription complex assembly The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex. go-plus.json MBF complex assembly|DSC1 transcription factor complex assembly|Mlu1-box binding factor assembly http://purl.obolibrary.org/obo/GO_0120185 GO:0120186 biolink:BiologicalProcess negative regulation of protein localization to chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin. go-plus.json negative regulation of protein localisation to chromatin http://purl.obolibrary.org/obo/GO_0120186 GO:0120187 biolink:BiologicalProcess positive regulation of protein localization to chromatin Any process that activates or increases the frequency, rate or extent of protein localization to chromatin. go-plus.json positive regulation of protein localisation to chromatin http://purl.obolibrary.org/obo/GO_0120187 CHEBI:61205 biolink:ChemicalSubstance docosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61205 CHEBI:36238 biolink:ChemicalSubstance 5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36238 GO:0120188 biolink:BiologicalProcess regulation of bile acid secretion Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0120188 GO:0120181 biolink:BiologicalProcess focal adhesion disassembly The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120181 GO:0120182 biolink:BiologicalProcess regulation of focal adhesion disassembly Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0120182 GO:0120183 biolink:BiologicalProcess positive regulation of focal adhesion disassembly Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0120183 GO:0120184 biolink:BiologicalProcess negative regulation of focal adhesion disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0120184 CHEBI:75840 biolink:ChemicalSubstance 2-keto-3-deoxy-L-galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75840 CHEBI:36232 biolink:ChemicalSubstance icosa-5,7,11,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36232 CHEBI:75841 biolink:ChemicalSubstance 1,2,3-tripalmitoleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75841 chebi_ph7_3 CHEBI:36233 biolink:ChemicalSubstance disaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36233 GO:0120180 biolink:BiologicalProcess cell-substrate junction disassembly The disaggregation of a cell-substrate junction into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0120180 CHEBI:26888 biolink:ChemicalSubstance tetrachlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_26888 CHEBI:75855 biolink:ChemicalSubstance 2,3-dilinolenoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75855 chebi_ph7_3 CHEBI:75856 biolink:ChemicalSubstance 3-methylfumaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75856 CHEBI:75853 biolink:ChemicalSubstance 2,3-dipalmitoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75853 chebi_ph7_3 CHEBI:75854 biolink:ChemicalSubstance 2,3-dilinoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75854 chebi_ph7_3 CHEBI:51847 biolink:ChemicalSubstance ketoester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51847 CHEBI:51848 biolink:ChemicalSubstance alpha-ketoester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51848 CHEBI:61211 biolink:ChemicalSubstance beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61211 CHEBI:51849 biolink:ChemicalSubstance beta-ketoester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51849 CHEBI:36203 biolink:ChemicalSubstance trioxilin A3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_36203 CHEBI:36204 biolink:ChemicalSubstance 12-hydroxylaurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36204 chebi_ph7_3 CHEBI:36201 biolink:ChemicalSubstance trioxilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_36201 CHEBI:36202 biolink:ChemicalSubstance all-cis-icosa-5,8,14-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36202 GO:0120196 biolink:BiologicalProcess negative regulation of anther dehiscence Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence. go-plus.json http://purl.obolibrary.org/obo/GO_0120196 GO:0120197 biolink:BiologicalProcess mucociliary clearance The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways. go-plus.json mucociliary transport|MCT|MCC http://purl.obolibrary.org/obo/GO_0120197 CHEBI:36208 biolink:ChemicalSubstance shikimate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36208 chebi_ph7_3 GO:0120198 biolink:BiologicalProcess positive regulation of imaginal disc-derived wing size Any process that increases the size of an imaginal disc-derived wing. go-plus.json http://purl.obolibrary.org/obo/GO_0120198 CHEBI:61216 biolink:ChemicalSubstance ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61216 chebi_ph7_3 CHEBI:36205 biolink:ChemicalSubstance cyclobutanedicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36205 GO:0120199 biolink:CellularComponent cone photoreceptor outer segment The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0120199 CHEBI:36206 biolink:ChemicalSubstance 3-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36206 GO:0120192 biolink:BiologicalProcess tight junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. go-plus.json occluding junction assembly|occluding cell junction assembly http://purl.obolibrary.org/obo/GO_0120192 GO:0120193 biolink:BiologicalProcess tight junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. go-plus.json occluding junction organization|occluding cell junction organization http://purl.obolibrary.org/obo/GO_0120193 GO:0120194 biolink:BiologicalProcess regulation of anther dehiscence Any process involved in the dehiscence of an anther to release the pollen grains contained within it. go-plus.json http://purl.obolibrary.org/obo/GO_0120194 GO:0120195 biolink:BiologicalProcess positive regulation of anther dehiscence Any process that activates or increases the frequency, rate or extent of anther dehiscence. go-plus.json http://purl.obolibrary.org/obo/GO_0120195 CHEBI:75851 biolink:ChemicalSubstance (2S,3R)-capreomycidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75851 CHEBI:36200 biolink:ChemicalSubstance hepoxilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_36200 CHEBI:75852 biolink:ChemicalSubstance 1,3-dilinolenoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75852 chebi_ph7_3 GO:0120190 biolink:BiologicalProcess negative regulation of bile acid secretion Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0120190 GO:0120191 biolink:BiologicalProcess negative regulation of termination of RNA polymerase II transcription Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription. go-plus.json repression of termination of RNA polymerase II transcription|down-regulation of RNA 3'-end formation by RNA polymerase II|negative regulation of RNA 3'-end formation by RNA polymerase II|downregulation of transcription termination from RNA polymerase II promoter|downregulation of transcription termination from Pol II promoter|down regulation of RNA polymerase II transcription termination|down regulation of transcription termination from Pol II promoter|down-regulation of termination of RNA polymerase II transcription|repression of transcription termination from RNA polymerase II promoter|downregulation of RNA polymerase II transcription termination|negative regulation of transcription termination from RNA polymerase II promoter|down regulation of RNA polymerase II transcription termination factor activity|down-regulation of transcription termination from RNA polymerase II promoter|downregulation of RNA polymerase II transcription termination factor activity|repression of RNA polymerase II transcription termination|repression of transcription termination from Pol II promoter|downregulation of termination of RNA polymerase II transcription|down regulation of RNA 3'-end formation by RNA polymerase II|down-regulation of RNA polymerase II transcription termination|negative regulation of RNA polymerase II transcription termination|down regulation of termination of RNA polymerase II transcription|downregulation of RNA 3'-end formation by RNA polymerase II|negative regulation of RNA polymerase II transcription termination factor activity|down-regulation of RNA polymerase II transcription termination factor activity|negative regulation of transcription termination from Pol II promoter|down-regulation of transcription termination from Pol II promoter|repression of RNA polymerase II transcription termination factor activity|repression of RNA 3'-end formation by RNA polymerase II|down regulation of transcription termination from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0120191 CHEBI:75850 biolink:ChemicalSubstance 1,3-dilinoleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75850 chebi_ph7_3 CHEBI:51833 biolink:ChemicalSubstance beta-D-fructofuranosyl alpha-D-mannopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_51833 chebi_ph7_3 CHEBI:75867 biolink:ChemicalSubstance 1-oleoyl-3-palmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75867 chebi_ph7_3 CHEBI:51834 biolink:ChemicalSubstance beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51834 CHEBI:51835 biolink:ChemicalSubstance microthecin go-plus.json http://purl.obolibrary.org/obo/CHEBI_51835 chebi_ph7_3 CHEBI:75865 biolink:ChemicalSubstance D-glucosaminic acid 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75865 CHEBI:51836 biolink:ChemicalSubstance 3,3'-biflaviolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_51836 CHEBI:26895 biolink:ChemicalSubstance tetracyclines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26895 CHEBI:75868 biolink:ChemicalSubstance 1-palmitoyl-3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75868 chebi_ph7_3 CHEBI:75869 biolink:ChemicalSubstance 1-oleoyl-3-palmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75869 chebi_ph7_3 CHEBI:26893 biolink:ChemicalSubstance tetracyclic triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26893 CHEBI:51837 biolink:ChemicalSubstance 3,8'-biflaviolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_51837 CHEBI:36218 biolink:ChemicalSubstance beta-lactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_36218 chebi_ph7_3 CHEBI:36219 biolink:ChemicalSubstance alpha-lactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_36219 chebi_ph7_3 CHEBI:12266 biolink:ChemicalSubstance 8-amino-7-oxononanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12266 CHEBI:61227 biolink:ChemicalSubstance beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61227 chebi_ph7_3 CHEBI:36210 biolink:ChemicalSubstance (S)-3-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36210 CHEBI:36211 biolink:ChemicalSubstance 2-hydroxydodecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36211 CHEBI:75860 biolink:ChemicalSubstance (3R)-citramalyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75860 CHEBI:51822 biolink:ChemicalSubstance 3,7-dideoxy-D-threo-hepto-2,6-diuolosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51822 CHEBI:51824 biolink:ChemicalSubstance N-(3-aminopropyl)-4-aminobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51824 CHEBI:75876 biolink:ChemicalSubstance (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75876 CHEBI:26863 biolink:ChemicalSubstance teasterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26863 chebi_ph7_3 CHEBI:75879 biolink:ChemicalSubstance 4-O-(beta-L-Araf-(1->2)-beta-L-Araf-(1->2)-beta-L-Araf)-cis-L-Hyp zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75879 chebi_ph7_3 GO:0120138 biolink:BiologicalProcess regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120138 CHEBI:61232 biolink:ChemicalSubstance N-acylphosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61232 GO:0120139 biolink:BiologicalProcess positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120139 CHEBI:61233 biolink:ChemicalSubstance spermidine hydroxycinnamic acid conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61233 CHEBI:85200 biolink:ChemicalSubstance N-icosenoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85200 chebi_ph7_3 CHEBI:61230 biolink:ChemicalSubstance beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61230 chebi_ph7_3 CHEBI:85201 biolink:ChemicalSubstance N-icosenoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85201 chebi_ph7_3 CHEBI:61231 biolink:ChemicalSubstance L-seryl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61231 chebi_ph7_3 GO:0120134 biolink:CellularComponent proximal portion of axoneme The portion of the axoneme that is close to the base of the cilium. go-plus.json proximal part of axoneme http://purl.obolibrary.org/obo/GO_0120134 GO:0120135 biolink:CellularComponent distal portion of axoneme The portion of the axoneme that is close to the tip of the cilium. go-plus.json distal part of axoneme http://purl.obolibrary.org/obo/GO_0120135 CHEBI:85204 biolink:ChemicalSubstance N-oleoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85204 chebi_ph7_3 GO:0120136 biolink:MolecularActivity dUMP kinase activity Catalysis of the reaction: ATP + dUMP = ADP + dUDP. RHEA:30655 go-plus.json deoxyuridine monophosphate kinase activity|ATP:dUMP phosphotransferase activity|dUMP-kinase activity http://purl.obolibrary.org/obo/GO_0120136 CHEBI:85205 biolink:ChemicalSubstance 3-hydroxytetradecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85205 GO:0120137 biolink:BiologicalProcess positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120137 CHEBI:85206 biolink:ChemicalSubstance N-arachidonoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85206 chebi_ph7_3 CHEBI:85207 biolink:ChemicalSubstance N-arachidonoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85207 chebi_ph7_3 CHEBI:85208 biolink:ChemicalSubstance 12-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85208 GO:0120132 biolink:BiologicalProcess positive regulation of apoptotic process in bone marrow cell Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow. go-plus.json positive regulation of bone marrow cell programmed cell death by apoptosis|positive regulation of bone marrow cell apoptosis|positive regulation of killing of bone marrow cells|activation of apoptosis in bone marrow|positive regulation of apoptotic process in bone marrow|up-regulation of apoptosis in bone marrow|up regulation of apoptosis in bone marrow|positive regulation of programmed cell death, bone marrow cells|positive regulation of apoptosis in bone marrow|positive regulation of programmed cell death of bone marrow cells by apoptosis|upregulation of apoptosis in bone marrow http://purl.obolibrary.org/obo/GO_0120132 CHEBI:85209 biolink:ChemicalSubstance 12-hydroxyoctadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85209 GO:0120133 biolink:BiologicalProcess negative regulation of actin cortical patch assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches. go-plus.json downregulation of actin cortical patch assembly|down-regulation of actin cortical patch assembly|inhibition of actin cortical patch assembly|down regulation of actin cortical patch assembly http://purl.obolibrary.org/obo/GO_0120133 CHEBI:75870 biolink:ChemicalSubstance 2-palmitoyl-3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75870 chebi_ph7_3 CHEBI:26878 biolink:ChemicalSubstance tertiary alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26878 chebi_ph7_3 CHEBI:26873 biolink:ChemicalSubstance terpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26873 CHEBI:26874 biolink:ChemicalSubstance terpenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26874 CHEBI:26875 biolink:ChemicalSubstance terpenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26875 CHEBI:26876 biolink:ChemicalSubstance terpineol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26876 CHEBI:61240 biolink:ChemicalSubstance beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61240 CHEBI:26872 biolink:ChemicalSubstance terpene ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26872 GO:0120149 biolink:CellularComponent host cell peroxisome A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. go-plus.json host peroxisome http://purl.obolibrary.org/obo/GO_0120149 CHEBI:61243 biolink:ChemicalSubstance beta-D-Galp-(1->3)-beta-D-GalpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_61243 chebi_ph7_3 GO:0120145 biolink:BiologicalProcess protein localization to basal ectoplasmic specialization A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization. go-plus.json protein localisation in basal ectoplasmic specialization|protein localization in basal ectoplasmic specialization|protein localisation to basal ectoplasmic specialization http://purl.obolibrary.org/obo/GO_0120145 CHEBI:61247 biolink:ChemicalSubstance beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61247 chebi_ph7_3 GO:0120146 biolink:MolecularActivity sulfatide binding Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group. go-plus.json sulfated galactocerebroside binding|3-O-sulfogalactosylceramide binding|SM4 binding http://purl.obolibrary.org/obo/GO_0120146 GO:0120147 biolink:MolecularActivity Formylglycine-generating oxidase activity Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O. MetaCyc:RXN-16226|EC:1.8.3.7|RHEA:51152 go-plus.json http://purl.obolibrary.org/obo/GO_0120147 GO:0120148 biolink:CellularComponent host cell centrosome A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. go-plus.json host centrosome http://purl.obolibrary.org/obo/GO_0120148 CHEBI:61246 biolink:ChemicalSubstance beta-D-Galp-(1->3)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_61246 chebi_ph7_3 GO:0120141 biolink:BiologicalProcess regulation of ecdysone receptor-mediated signaling pathway Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120141 GO:0120142 biolink:BiologicalProcess positive regulation of ecdysone receptor-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120142 GO:0120143 biolink:BiologicalProcess negative regulation of ecdysone receptor-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120143 CHEBI:61249 biolink:ChemicalSubstance hesperetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61249 CHEBI:75880 biolink:ChemicalSubstance 4-O-(beta-L-Araf)-cis-L-Hyp zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75880 chebi_ph7_3 GO:0120140 biolink:BiologicalProcess negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0120140 CHEBI:75884 biolink:ChemicalSubstance N-acylindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_75884 CHEBI:75885 biolink:ChemicalSubstance 2-pyranones go-plus.json http://purl.obolibrary.org/obo/CHEBI_75885 CHEBI:75882 biolink:ChemicalSubstance 1-alkyl-2-acetylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75882 chebi_ph7_3 CHEBI:75883 biolink:ChemicalSubstance monoalkylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75883 CHEBI:26845 biolink:ChemicalSubstance tagaturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26845 CHEBI:51802 biolink:ChemicalSubstance 4H-imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_51802 chebi_ph7_3 CHEBI:26847 biolink:ChemicalSubstance altraric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26847 CHEBI:26841 biolink:ChemicalSubstance synthetic auxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26841 CHEBI:61251 biolink:ChemicalSubstance alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61251 CHEBI:85220 biolink:ChemicalSubstance N-acetyl-D-methionine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85220 chebi_ph7_3 CHEBI:61254 biolink:ChemicalSubstance alpha-D-glucosyl ditrans,polycis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61254 chebi_ph7_3 CHEBI:85221 biolink:ChemicalSubstance N-icosanoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85221 chebi_ph7_3 CHEBI:85222 biolink:ChemicalSubstance N,1-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85222 chebi_ph7_3 CHEBI:85223 biolink:ChemicalSubstance N-arachidonoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85223 chebi_ph7_3 CHEBI:61252 biolink:ChemicalSubstance alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61252 chebi_ph7_3 CHEBI:61253 biolink:ChemicalSubstance alpha-D-glucosyl ditrans,polycis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61253 CHEBI:85225 biolink:ChemicalSubstance N-acyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85225 chebi_ph7_3 GO:0120157 biolink:CellularComponent PAR polarity complex A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. go-plus.json PAR6-PAR3-aPKC complex|BEM1-CDC24-CLA4 complex|PAR3-PAR6-atypical PKC|Cdc42p GEF-PAK complex|apical polarity complex|PAR3/PAR6/aPKC http://purl.obolibrary.org/obo/GO_0120157 CHEBI:85226 biolink:ChemicalSubstance N-hexadecanoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85226 chebi_ph7_3 GO:0120158 biolink:BiologicalProcess positive regulation of collagen catabolic process Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. go-plus.json up-regulation of collagen catabolic process|activation of collagen catabolic process|positive regulation of collagen degradation|positive regulation of collagen catabolism|positive regulation of collagen breakdown|up regulation of collagen catabolic process|upregulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0120158 CHEBI:85227 biolink:ChemicalSubstance N-octadecanoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85227 chebi_ph7_3 GO:0120159 biolink:MolecularActivity rRNA pseudouridine synthase activity Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. EC:5.4.99.19|EC:5.4.99.29|EC:5.4.99.24|EC:5.4.99.23|EC:5.4.99.22|EC:5.4.99.43|EC:5.4.99.21|EC:5.4.99.20 go-plus.json 23S rRNA pseudouridine(2605) synthase|23S rRNA pseudouridine(1911/1915/1917) synthase|23S rRNA pseudouridine(2604) synthase|23S rRNA pseudouridine(2457) synthase|16S rRNA pseudouridine(516) synthase|23S rRNA pseudouridine(746) synthase|21S rRNA pseudouridine(2819) synthase|23S rRNA pseudouridine(955/2504/2580) synthase http://purl.obolibrary.org/obo/GO_0120159 CHEBI:85228 biolink:ChemicalSubstance N-icosanoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85228 chebi_ph7_3 GO:0120152 biolink:MolecularActivity calcium-dependent outer dynein arm binding Binding to an outer dynein arm in the presence of calcium. go-plus.json http://purl.obolibrary.org/obo/GO_0120152 CHEBI:85229 biolink:ChemicalSubstance N-oleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85229 chebi_ph7_3 GO:0120153 biolink:MolecularActivity calcium-dependent carbohydrate binding Binding to a carbohydrate in the presence of calcium. go-plus.json http://purl.obolibrary.org/obo/GO_0120153 GO:0120154 biolink:BiologicalProcess negative regulation of ERBB4 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0120154 GO:0120155 biolink:CellularComponent MIH complex A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins. go-plus.json Mlc1p-Iqg1p-Hof1p complex http://purl.obolibrary.org/obo/GO_0120155 GO:0120150 biolink:BiologicalProcess regulation of mitotic actomyosin contractile ring disassembly Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly. go-plus.json regulation of mitotic cytokinetic ring disassembly|regulation of mitotic actomyosin ring disassembly|regulation of mitotic CAR disassembly|regulation of mitotic constriction ring disassembly|regulation of mitotic contractile actomyosin ring disassembly http://purl.obolibrary.org/obo/GO_0120150 GO:0120151 biolink:BiologicalProcess positive regulation of mitotic actomyosin contractile ring disassembly Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly. go-plus.json positive regulation of mitotic actomyosin ring disassembly|positive regulation of mitotic CAR disassembly|positive regulation of mitotic constriction ring disassembly|positive regulation of mitotic cytokinetic ring disassembly|positive regulation of mitotic contractile actomyosin ring disassembly http://purl.obolibrary.org/obo/GO_0120151 CHEBI:75890 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75890 CHEBI:75895 biolink:ChemicalSubstance N(alpha)-methyl-L-histidine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75895 chebi_ph7_3 CHEBI:26848 biolink:ChemicalSubstance tannin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26848 CHEBI:26849 biolink:ChemicalSubstance tartaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26849 CHEBI:75894 biolink:ChemicalSubstance 4-O-(beta-L-Araf-(1->2)-beta-L-Araf-(1->2)-beta-L-Araf)-cis-L-Hyp go-plus.json http://purl.obolibrary.org/obo/CHEBI_75894 CHEBI:85210 biolink:ChemicalSubstance N-acetyl-D-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85210 CHEBI:61265 biolink:ChemicalSubstance (beta-D-glucopyranosyloxymethyl)deoxyuridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61265 CHEBI:85211 biolink:ChemicalSubstance 15-hydroxypentadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85211 CHEBI:61266 biolink:ChemicalSubstance hemicellulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61266 CHEBI:85212 biolink:ChemicalSubstance omega-hydroxy fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85212 CHEBI:61264 biolink:ChemicalSubstance pectic arabinan go-plus.json http://purl.obolibrary.org/obo/CHEBI_61264 CHEBI:85213 biolink:ChemicalSubstance 16-hydroxyhexadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85213 CHEBI:85214 biolink:ChemicalSubstance 9-decenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85214 CHEBI:61269 biolink:ChemicalSubstance scopolamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61269 GO:0120168 biolink:BiologicalProcess detection of hot stimulus involved in thermoception The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception. go-plus.json thermoception, sensory detection of heat stimulus|thermoception, sensory transduction of heat stimulus|sensory transduction of hot stimulus during thermoception|thermoception, sensory transduction of hot stimulus|thermoception, sensory detection of hot stimulus|sensory detection of hot stimulus during thermoception|sensory detection of heat stimulus during thermoception|sensory transduction of heat stimulus during thermoception http://purl.obolibrary.org/obo/GO_0120168 CHEBI:85215 biolink:ChemicalSubstance 1-myristoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85215 GO:0120169 biolink:BiologicalProcess detection of cold stimulus involved in thermoception The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception. go-plus.json sensory detection of cold stimulus during thermoception|sensory transduction of cold stimulus during thermoception|thermoception, sensory detection of cold stimulus|thermoception, sensory transduction of cold stimulus http://purl.obolibrary.org/obo/GO_0120169 CHEBI:85216 biolink:ChemicalSubstance N-acyllysophosphatidylethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85216 chebi_ph7_3 CHEBI:61267 biolink:ChemicalSubstance 5-nitroanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61267 chebi_ph7_3 CHEBI:85217 biolink:ChemicalSubstance N-palmitoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85217 chebi_ph7_3 CHEBI:61268 biolink:ChemicalSubstance 5-nitrosalicylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61268 chebi_ph7_3 GO:0120163 biolink:BiologicalProcess negative regulation of cold-induced thermogenesis Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis. go-plus.json negative regulation of CIT http://purl.obolibrary.org/obo/GO_0120163 GO:0120164 biolink:BiologicalProcess conidium germination The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination. go-plus.json http://purl.obolibrary.org/obo/GO_0120164 CHEBI:85219 biolink:ChemicalSubstance N-stearoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85219 chebi_ph7_3 GO:0120165 biolink:BiologicalProcess perithecium development The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck. go-plus.json http://purl.obolibrary.org/obo/GO_0120165 GO:0120166 biolink:BiologicalProcess protoperithecium formation The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium. go-plus.json http://purl.obolibrary.org/obo/GO_0120166 GO:0120160 biolink:MolecularActivity intraciliary transport particle A binding Binding to an intraciliary transport particle A (IFT A) complex. go-plus.json intraflagellar transport complex A binding|IFT A complex binding|intraciliary transport complex A binding|intraflagellar transport particle A binding http://purl.obolibrary.org/obo/GO_0120160 GO:0120161 biolink:BiologicalProcess regulation of cold-induced thermogenesis Any process that modulates the frequency, rate or extent of cold-induced thermogenesis. go-plus.json regulation of CIT http://purl.obolibrary.org/obo/GO_0120161 GO:0120162 biolink:BiologicalProcess positive regulation of cold-induced thermogenesis Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis. go-plus.json positive regulation of CIT http://purl.obolibrary.org/obo/GO_0120162 GO:0036516 biolink:BiologicalProcess chemoattraction of dopaminergic neuron axon The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. go-plus.json chemoattraction of DA axon|chemoattraction of dopaminergic axon http://purl.obolibrary.org/obo/GO_0036516 GO:0036517 biolink:BiologicalProcess chemoattraction of serotonergic neuron axon The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. go-plus.json chemoattraction of serotonergic axon|chemoattraction of 5-HT axon http://purl.obolibrary.org/obo/GO_0036517 GO:1901048 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. go-plus.json TGF-beta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of multicellular organism growth|TGFbeta receptor signaling pathway of regulation of body size|transforming growth factor beta receptor signalling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signalling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signaling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of body size|TGF-beta receptor signaling pathway of regulation of body growth|TGF-beta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of body growth|transforming growth factor beta receptor signalling pathway of regulation of body growth http://purl.obolibrary.org/obo/GO_1901048 GO:0036518 biolink:BiologicalProcess chemorepulsion of dopaminergic neuron axon The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. go-plus.json chemorepulsion of DA axon|chemorepulsion of dopaminergic axon http://purl.obolibrary.org/obo/GO_0036518 GO:1901049 biolink:BiologicalProcess atropine metabolic process The chemical reactions and pathways involving atropine. go-plus.json atropine metabolism http://purl.obolibrary.org/obo/GO_1901049 GO:0036519 biolink:BiologicalProcess chemorepulsion of serotonergic neuron axon The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. go-plus.json chemorepulsion of serotonergic axon|chemorepulsion of 5-HT axon http://purl.obolibrary.org/obo/GO_0036519 GO:1901046 biolink:BiologicalProcess positive regulation of oviposition Any process that activates or increases the frequency, rate or extent of oviposition. go-plus.json positive regulation of egg laying|up regulation of egg laying|up-regulation of oviposition|up-regulation of egg-laying|upregulation of oviposition|upregulation of egg laying|activation of egg-laying|positive regulation of egg-laying|up regulation of egg-laying|up-regulation of egg laying|up regulation of oviposition|activation of oviposition|activation of egg laying|upregulation of egg-laying http://purl.obolibrary.org/obo/GO_1901046 GO:1901047 biolink:BiologicalProcess insulin receptor signaling pathway involved in determination of adult lifespan The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle. go-plus.json daf-2 receptor signaling pathway of determination of adult lifespan|insulin receptor signalling pathway of determination of adult lifespan|insulin receptor signaling pathway of determination of adult lifespan http://purl.obolibrary.org/obo/GO_1901047 GO:1901044 biolink:BiologicalProcess protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1901044 GO:1901045 biolink:BiologicalProcess negative regulation of oviposition Any process that stops, prevents or reduces the frequency, rate or extent of oviposition. go-plus.json inhibition of oviposition|inhibition of egg-laying|downregulation of egg laying|down regulation of egg laying|down regulation of oviposition|down-regulation of egg-laying|negative regulation of egg-laying|inhibition of egg laying|downregulation of oviposition|downregulation of egg-laying|down-regulation of oviposition|down regulation of egg-laying|down-regulation of egg laying|negative regulation of egg laying http://purl.obolibrary.org/obo/GO_1901045 GO:1901053 biolink:BiologicalProcess sarcosine catabolic process The chemical reactions and pathways resulting in the breakdown of sarcosine. go-plus.json sarcosine catabolism|sarcosine degradation|sarcosine breakdown http://purl.obolibrary.org/obo/GO_1901053 GO:1901054 biolink:BiologicalProcess sarcosine biosynthetic process The chemical reactions and pathways resulting in the formation of sarcosine. go-plus.json sarcosine anabolism|sarcosine synthesis|sarcosine biosynthesis|sarcosine formation http://purl.obolibrary.org/obo/GO_1901054 GO:1901051 biolink:BiologicalProcess atropine biosynthetic process The chemical reactions and pathways resulting in the formation of atropine. go-plus.json atropine formation|atropine biosynthesis|atropine anabolism|atropine synthesis http://purl.obolibrary.org/obo/GO_1901051 GO:0036510 biolink:BiologicalProcess trimming of terminal mannose on C branch The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. go-plus.json conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2|glycoprotein mannose trimming on C branch|conversion of M9 to M8C http://purl.obolibrary.org/obo/GO_0036510 GO:0036511 biolink:BiologicalProcess trimming of first mannose on A branch The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. go-plus.json conversion of (Man)9(GlcNAc)2 to (Man)8A(GlcNAc)2|conversion of M9 to M8A|glycoprotein mannose trimming on A branch http://purl.obolibrary.org/obo/GO_0036511 GO:1901052 biolink:BiologicalProcess sarcosine metabolic process The chemical reactions and pathways involving sarcosine. go-plus.json sarcosine metabolism http://purl.obolibrary.org/obo/GO_1901052 GO:0036512 biolink:BiologicalProcess trimming of second mannose on A branch The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. go-plus.json conversion of (Man)8A(GlcNAc)2 to (Man)7AA(GlcNAc)2|conversion of M8A to M7AA|glycoprotein mannose trimming on A branch http://purl.obolibrary.org/obo/GO_0036512 GO:0036513 biolink:CellularComponent Derlin-1 retrotranslocation complex A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel. go-plus.json Derlin-1 protein dislocation complex|Derlin-1 complex|ERAD protein dislocation complex|Derlin-1 retro-translocation complex|Derlin-1 retrotranslocon http://purl.obolibrary.org/obo/GO_0036513 GO:1901050 biolink:BiologicalProcess atropine catabolic process The chemical reactions and pathways resulting in the breakdown of atropine. go-plus.json atropine catabolism|atropine degradation|atropine breakdown http://purl.obolibrary.org/obo/GO_1901050 GO:0036514 biolink:BiologicalProcess dopaminergic neuron axon guidance The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json mdDA axon guidance|dopaminergic axon guidance|DA axon guidance http://purl.obolibrary.org/obo/GO_0036514 GO:0036515 biolink:BiologicalProcess serotonergic neuron axon guidance The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json 5-HT axon guidance|serotonergic axon guidance http://purl.obolibrary.org/obo/GO_0036515 GO:0036505 biolink:MolecularActivity prosaposin receptor activity Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D). go-plus.json prosaposin-activated receptor activity http://purl.obolibrary.org/obo/GO_0036505 GO:0036506 biolink:BiologicalProcess maintenance of unfolded protein Maintaining a protein in an unfolded, soluble state. go-plus.json http://purl.obolibrary.org/obo/GO_0036506 GO:0036507 biolink:BiologicalProcess protein demannosylation The removal of one or more mannose residues from a mannosylated protein. go-plus.json protein de-mannosylation http://purl.obolibrary.org/obo/GO_0036507 GO:1901059 biolink:BiologicalProcess p-hydroxyphenyl lignin catabolic process The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin. go-plus.json H-lignin catabolic process|p-hydroxyphenyl lignin catabolism|p-hydroxyphenyl lignin degradation|p-hydroxyphenyl lignin breakdown http://purl.obolibrary.org/obo/GO_1901059 GO:0036508 biolink:BiologicalProcess protein alpha-1,2-demannosylation The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein. go-plus.json glycoprotein mannose trimming|mannose trimming http://purl.obolibrary.org/obo/GO_0036508 GO:1901057 biolink:BiologicalProcess trimethylenediamine biosynthetic process The chemical reactions and pathways resulting in the formation of trimethylenediamine. go-plus.json trimethylenediamine anabolism|trimethylenediamine synthesis|trimethylenediamine biosynthesis|trimethylenediamine formation http://purl.obolibrary.org/obo/GO_1901057 GO:0036509 biolink:BiologicalProcess trimming of terminal mannose on B branch The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. KEGG_REACTION:R06722 go-plus.json glycoprotein mannose trimming on B branch|conversion of (Man)9(GlcNAc)2 to (Man)8B(GlcNAc)2|conversion of M9 to M8B http://purl.obolibrary.org/obo/GO_0036509 GO:1901058 biolink:BiologicalProcess p-hydroxyphenyl lignin metabolic process The chemical reactions and pathways involving p-hydroxyphenyl lignin. go-plus.json H-lignin metabolic process|p-hydroxyphenyl lignin metabolism http://purl.obolibrary.org/obo/GO_1901058 GO:1901055 biolink:BiologicalProcess trimethylenediamine metabolic process The chemical reactions and pathways involving trimethylenediamine. go-plus.json trimethylenediamine metabolism http://purl.obolibrary.org/obo/GO_1901055 GO:1901056 biolink:BiologicalProcess trimethylenediamine catabolic process The chemical reactions and pathways resulting in the breakdown of trimethylenediamine. go-plus.json trimethylenediamine catabolism|trimethylenediamine degradation|trimethylenediamine breakdown http://purl.obolibrary.org/obo/GO_1901056 GO:1901064 biolink:BiologicalProcess syringal lignin metabolic process The chemical reactions and pathways involving syringal lignin. go-plus.json syringal lignin metabolism|S-lignin metabolic process http://purl.obolibrary.org/obo/GO_1901064 CHEBI:131561 biolink:ChemicalSubstance hyaluronic acid synthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_131561 GO:1901065 biolink:BiologicalProcess syringal lignin catabolic process The chemical reactions and pathways resulting in the breakdown of syringal lignin. go-plus.json syringal lignin degradation|syringal lignin breakdown|syringal lignin catabolism|S-lignin catabolic process http://purl.obolibrary.org/obo/GO_1901065 CHEBI:131562 biolink:ChemicalSubstance (5S,15S)-5-hydroperoxy-15-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_131562 GO:1901062 biolink:BiologicalProcess guaiacyl lignin catabolic process The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin. go-plus.json guaiacyl lignin breakdown|guaiacyl lignin catabolism|G-lignin catabolic process|guaiacyl lignin degradation http://purl.obolibrary.org/obo/GO_1901062 GO:0036500 biolink:BiologicalProcess ATF6-mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity. go-plus.json UPR signaling by ATF6 stress sensor|ATF6 signaling in response to endoplasmic reticulum stress|ATF6-alpha UPR branch|ATF6 signal transduction pathway|ATF6-beta UPR branch|endoplasmic reticulum unfolded protein response; ATF6 signaling|ATF6 branch of UPR|activating transcription factor 6 signaling in unfolded protein response http://purl.obolibrary.org/obo/GO_0036500 GO:1901063 biolink:BiologicalProcess guaiacyl lignin biosynthetic process The chemical reactions and pathways resulting in the formation of guaiacyl lignin. go-plus.json G-lignin biosynthetic process|guaiacyl lignin anabolism|guaiacyl lignin synthesis|guaiacyl lignin formation|guaiacyl lignin biosynthesis http://purl.obolibrary.org/obo/GO_1901063 GO:1901060 biolink:BiologicalProcess p-hydroxyphenyl lignin biosynthetic process The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin. go-plus.json p-hydroxyphenyl lignin anabolism|p-hydroxyphenyl lignin synthesis|p-hydroxyphenyl lignin formation|p-hydroxyphenyl lignin biosynthesis|H-lignin biosynthetic process http://purl.obolibrary.org/obo/GO_1901060 GO:0036501 biolink:CellularComponent UFD1-NPL4 complex A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p. go-plus.json Ufd1/Npl4 complex|UFD1L-NPLOC4 complex|Npl4p-Ufd1p complex|Ufd1-Npl4 binary complex|Ufd1-Npl4 cofactor complex http://purl.obolibrary.org/obo/GO_0036501 CHEBI:131564 biolink:ChemicalSubstance (5S,15S)-5-hydroperoxy-15-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131564 chebi_ph7_3 GO:1901061 biolink:BiologicalProcess guaiacyl lignin metabolic process The chemical reactions and pathways involving guaiacyl lignin. go-plus.json G-lignin metabolic process|guaiacyl lignin metabolism http://purl.obolibrary.org/obo/GO_1901061 GO:0036502 biolink:CellularComponent Derlin-1-VIMP complex A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome. go-plus.json Derlin-1/VIMP complex http://purl.obolibrary.org/obo/GO_0036502 CHEBI:131565 biolink:ChemicalSubstance steroid aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_131565 GO:0036503 biolink:BiologicalProcess ERAD pathway The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. go-plus.json protein degradation by ERAD|ER-associated degradation pathway|endoplasmic reticulum-associated degradation|endoplasmic reticulum-associated protein degradation pathway http://purl.obolibrary.org/obo/GO_0036503 GO:0036504 biolink:BiologicalProcess Golgi membrane fusion The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. go-plus.json membrane fusion involved in Golgi reassembly|post-mitotic fusion of Golgi membranes http://purl.obolibrary.org/obo/GO_0036504 GO:1901068 biolink:BiologicalProcess guanosine-containing compound metabolic process The chemical reactions and pathways involving guanosine-containing compounds (guanosines). go-plus.json guanosines metabolism|guanosine-containing compound metabolism|guanosines metabolic process http://purl.obolibrary.org/obo/GO_1901068 GO:1901069 biolink:BiologicalProcess guanosine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines). go-plus.json guanosines catabolism|guanosine-containing compound catabolism|guanosines degradation|guanosine-containing compound degradation|guanosines breakdown|guanosine-containing compound breakdown|guanosines catabolic process http://purl.obolibrary.org/obo/GO_1901069 GO:1901066 biolink:BiologicalProcess syringal lignin biosynthetic process The chemical reactions and pathways resulting in the formation of syringal lignin. go-plus.json syringal lignin biosynthesis|syringal lignin anabolism|syringal lignin synthesis|syringal lignin formation|S-lignin biosynthetic process http://purl.obolibrary.org/obo/GO_1901066 GO:1901067 biolink:BiologicalProcess ferulate catabolic process The chemical reactions and pathways resulting in the breakdown of ferulate. go-plus.json ferulate degradation|ferulate breakdown|ferulate catabolism http://purl.obolibrary.org/obo/GO_1901067 GO:1901075 biolink:BiologicalProcess negative regulation of engulfment of apoptotic cell Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell. go-plus.json down regulation of engulfment of cell corpse|downregulation of engulfment of apoptotic cell corpse|downregulation of engulfment of cell corpse|downregulation of engulfment of apoptotic cell|down regulation of engulfment of apoptotic cell|down-regulation of engulfment of apoptotic cell corpse|negative regulation of engulfment of apoptotic cell corpse|inhibition of engulfment of apoptotic cell|negative regulation of engulfment of cell corpse|down-regulation of engulfment of cell corpse|inhibition of engulfment of apoptotic cell corpse|inhibition of engulfment of cell corpse|down-regulation of engulfment of apoptotic cell|down regulation of engulfment of apoptotic cell corpse http://purl.obolibrary.org/obo/GO_1901075 GO:1901076 biolink:BiologicalProcess positive regulation of engulfment of apoptotic cell Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell. go-plus.json up regulation of engulfment of apoptotic cell|up regulation of engulfment of apoptotic cell corpse|activation of engulfment of apoptotic cell corpse|positive regulation of engulfment of apoptotic cell corpse|up regulation of engulfment of cell corpse|activation of engulfment of cell corpse|positive regulation of engulfment of cell corpse|upregulation of engulfment of apoptotic cell|up-regulation of engulfment of apoptotic cell corpse|up-regulation of engulfment of cell corpse|activation of engulfment of apoptotic cell|up-regulation of engulfment of apoptotic cell|upregulation of engulfment of apoptotic cell corpse|upregulation of engulfment of cell corpse http://purl.obolibrary.org/obo/GO_1901076 GO:1901073 biolink:BiologicalProcess glucosamine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines). go-plus.json glucosamines anabolism|glucosamines synthesis|glucosamines formation|glucosamine-containing compound anabolism|glucosamines biosynthetic process|glucosamine-containing compound synthesis|glucosamine-containing compound biosynthesis|glucosamine-containing compound formation|glucosamines biosynthesis http://purl.obolibrary.org/obo/GO_1901073 CHEBI:131530 biolink:ChemicalSubstance pyridoxal(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131530 GO:1901074 biolink:BiologicalProcess regulation of engulfment of apoptotic cell Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell. go-plus.json regulation of engulfment of cell corpse|regulation of engulfment of apoptotic cell corpse http://purl.obolibrary.org/obo/GO_1901074 GO:1901071 biolink:BiologicalProcess glucosamine-containing compound metabolic process The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines). go-plus.json glucosamines metabolic process|glucosamine-containing compound metabolism|glucosamines metabolism http://purl.obolibrary.org/obo/GO_1901071 GO:1901072 biolink:BiologicalProcess glucosamine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines). go-plus.json glucosamine-containing compound breakdown|glucosamine-containing compound catabolism|glucosamines catabolic process|glucosamines degradation|glucosamines catabolism|glucosamines breakdown|glucosamine-containing compound degradation http://purl.obolibrary.org/obo/GO_1901072 CHEBI:131533 biolink:ChemicalSubstance pyridoxamine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131533 GO:1901070 biolink:BiologicalProcess guanosine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines). go-plus.json guanosines anabolism|guanosine-containing compound anabolism|guanosines synthesis|guanosine-containing compound synthesis|guanosines formation|guanosine-containing compound formation|guanosines biosynthesis|guanosines biosynthetic process|guanosine-containing compound biosynthesis http://purl.obolibrary.org/obo/GO_1901070 CHEBI:36281 biolink:ChemicalSubstance caffeic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36281 GO:1901079 biolink:BiologicalProcess positive regulation of relaxation of muscle Any process that activates or increases the frequency, rate or extent of relaxation of muscle. go-plus.json upregulation of relaxation of muscle|up-regulation of relaxation of muscle|activation of relaxation of muscle|up regulation of relaxation of muscle http://purl.obolibrary.org/obo/GO_1901079 GO:1901077 biolink:BiologicalProcess regulation of relaxation of muscle Any process that modulates the frequency, rate or extent of relaxation of muscle. go-plus.json http://purl.obolibrary.org/obo/GO_1901077 GO:1901078 biolink:BiologicalProcess negative regulation of relaxation of muscle Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle. go-plus.json down regulation of relaxation of muscle|inhibition of relaxation of muscle|down-regulation of relaxation of muscle|downregulation of relaxation of muscle http://purl.obolibrary.org/obo/GO_1901078 GO:1901086 biolink:BiologicalProcess benzylpenicillin metabolic process The chemical reactions and pathways involving benzylpenicillin. go-plus.json penicillin G metabolism|benzylpenicillin metabolism http://purl.obolibrary.org/obo/GO_1901086 GO:1901087 biolink:BiologicalProcess benzylpenicillin catabolic process The chemical reactions and pathways resulting in the breakdown of benzylpenicillin. go-plus.json benzylpenicillin breakdown|penicillin G catabolism|penicillin G degradation|benzylpenicillin catabolism|penicillin G breakdown|penicillin G catabolic process|benzylpenicillin degradation http://purl.obolibrary.org/obo/GO_1901087 GO:1901084 biolink:BiologicalProcess pyrrolizidine alkaloid catabolic process The chemical reactions and pathways resulting in the breakdown of pyrrolizidine alkaloid. go-plus.json pyrrolizidine alkaloid catabolism|pyrrolizidine alkaloid degradation|pyrrolizidine alkaloid breakdown http://purl.obolibrary.org/obo/GO_1901084 GO:1901085 biolink:BiologicalProcess pyrrolizidine alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid. go-plus.json pyrrolizidine alkaloid biosynthesis|pyrrolizidine alkaloid anabolism|pyrrolizidine alkaloid synthesis|pyrrolizidine alkaloid formation http://purl.obolibrary.org/obo/GO_1901085 GO:1901082 biolink:BiologicalProcess positive regulation of relaxation of smooth muscle Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle. go-plus.json up regulation of relaxation of smooth muscle|positive regulation of smooth muscle relaxation|activation of relaxation of smooth muscle|up regulation of smooth muscle relaxation|up-regulation of relaxation of smooth muscle|upregulation of smooth muscle relaxation|up-regulation of smooth muscle relaxation|upregulation of relaxation of smooth muscle|activation of smooth muscle relaxation http://purl.obolibrary.org/obo/GO_1901082 GO:1901083 biolink:BiologicalProcess pyrrolizidine alkaloid metabolic process The chemical reactions and pathways involving pyrrolizidine alkaloid. go-plus.json pyrrolizidine alkaloid metabolism http://purl.obolibrary.org/obo/GO_1901083 GO:1901080 biolink:BiologicalProcess regulation of relaxation of smooth muscle Any process that modulates the frequency, rate or extent of relaxation of smooth muscle. go-plus.json regulation of smooth muscle relaxation http://purl.obolibrary.org/obo/GO_1901080 GO:1901081 biolink:BiologicalProcess negative regulation of relaxation of smooth muscle Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle. go-plus.json down-regulation of relaxation of smooth muscle|downregulation of smooth muscle relaxation|down regulation of smooth muscle relaxation|inhibition of relaxation of smooth muscle|inhibition of smooth muscle relaxation|down regulation of relaxation of smooth muscle|down-regulation of smooth muscle relaxation|negative regulation of smooth muscle relaxation|downregulation of relaxation of smooth muscle http://purl.obolibrary.org/obo/GO_1901081 CHEBI:36299 biolink:ChemicalSubstance tricarboxylic acid monoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36299 GO:0012505 biolink:CellularComponent endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. Wikipedia:Endomembrane_system go-plus.json http://purl.obolibrary.org/obo/GO_0012505 goslim_flybase_ribbon|goslim_yeast|goslim_candida|goslim_aspergillus GO:0012506 biolink:CellularComponent vesicle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell. NIF_Subcellular:sao1153182838 go-plus.json http://purl.obolibrary.org/obo/GO_0012506 GO:0012503 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0012503 GO:0012504 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0012504 GO:0012509 biolink:CellularComponent inter-Golgi transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances within the Golgi. go-plus.json inter-Golgi transport constitutive secretory pathway transport vesicle membrane http://purl.obolibrary.org/obo/GO_0012509 GO:0012507 biolink:CellularComponent ER to Golgi transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi. go-plus.json ER-Golgi transport vesicle membrane|ER to Golgi constitutive secretory pathway transport vesicle membrane|endoplasmic reticulum-Golgi transport vesicle membrane|COPII coated vesicle membrane|endoplasmic reticulum to Golgi transport vesicle membrane http://purl.obolibrary.org/obo/GO_0012507 GO:1901088 biolink:BiologicalProcess benzylpenicillin biosynthetic process The chemical reactions and pathways resulting in the formation of benzylpenicillin. go-plus.json penicillin G anabolism|penicillin G synthesis|benzylpenicillin anabolism|penicillin G formation|benzylpenicillin synthesis|benzylpenicillin biosynthesis|benzylpenicillin formation|penicillin G biosynthesis http://purl.obolibrary.org/obo/GO_1901088 GO:0012508 biolink:CellularComponent Golgi to ER transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER. go-plus.json Golgi-ER transport vesicle membrane|Golgi to ER constitutive secretory pathway transport vesicle membrane|Golgi to endoplasmic reticulum transport vesicle membrane|Golgi-endoplasmic reticulum transport vesicle membrane http://purl.obolibrary.org/obo/GO_0012508 GO:1901089 biolink:BiologicalProcess acetate ester metabolic process involved in fermentation Any acetate ester metabolic process that is involved in fermentation. go-plus.json acetate ester metabolic process during fermentation http://purl.obolibrary.org/obo/GO_1901089 GO:1901097 biolink:BiologicalProcess negative regulation of autophagosome maturation Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation. go-plus.json inhibition of amphisome-lysosome fusion|inhibition of autophagic vacuole fusion|inhibition of autophagosome maturation|inhibition of autolysosome formation|negative regulation of autophagic vacuole fusion|down-regulation of autophagic vacuole maturation|down regulation of amphisome-lysosome fusion|down-regulation of fusion of autophagosome with lysosome|negative regulation of fusion of autophagosome with lysosome|downregulation of amphisome-lysosome fusion|down regulation of autophagic vacuole fusion|inhibition of autophagic vacuole maturation|down-regulation of autophagosome maturation|negative regulation of autolysosome formation|down-regulation of autolysosome formation|negative regulation of autophagosome maturation|downregulation of autophagic vacuole fusion|negative regulation of autophagosome fusion|inhibition of fusion of autophagosome with lysosome|down-regulation of amphisome-lysosome fusion|negative regulation of amphisome-lysosome fusion|downregulation of autophagosome maturation|downregulation of autolysosome formation|down regulation of autophagic vacuole maturation|down regulation of fusion of autophagosome with lysosome|down-regulation of autophagic vacuole fusion|down regulation of autophagosome maturation|down regulation of autolysosome formation|downregulation of autophagic vacuole maturation|downregulation of fusion of autophagosome with lysosome http://purl.obolibrary.org/obo/GO_1901097 GO:1901098 biolink:BiologicalProcess positive regulation of autophagosome maturation Any process that activates or increases the frequency, rate or extent of autophagosome maturation. go-plus.json up regulation of autophagic vacuole maturation|up-regulation of autophagic vacuole fusion|up regulation of fusion of autophagosome with lysosome|activation of autophagic vacuole maturation|positive regulation of autophagic vacuole fusion|positive regulation of fusion of autophagosome with lysosome|upregulation of amphisome-lysosome fusion|up-regulation of autophagosome maturation|up-regulation of autolysosome formation|activation of fusion of autophagosome with lysosome|upregulation of autophagic vacuole fusion|activation of autolysosome formation|activation of autophagosome maturation|up-regulation of autophagic vacuole maturation|up regulation of amphisome-lysosome fusion|up-regulation of fusion of autophagosome with lysosome|positive regulation of amphisome-lysosome fusion|positive regulation of autolysosome formation|positive regulation of autophagosome maturation|up regulation of autophagosome maturation|up regulation of autophagic vacuole fusion|up regulation of autolysosome formation|activation of amphisome-lysosome fusion|upregulation of autophagic vacuole maturation|activation of autophagic vacuole fusion|positive regulation of autophagosome fusion|upregulation of fusion of autophagosome with lysosome|up-regulation of amphisome-lysosome fusion|upregulation of autophagosome maturation|upregulation of autolysosome formation http://purl.obolibrary.org/obo/GO_1901098 GO:1901095 biolink:BiologicalProcess positive regulation of protein homotetramerization Any process that activates or increases the frequency, rate or extent of protein homotetramerization. go-plus.json upregulation of protein homotetramer formation|upregulation of protein homotetramer assembly|upregulation of protein homotetramerization|up regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer biosynthesis|activation of protein homotetramer biosynthetic process|activation of protein homotetramer biosynthesis|positive regulation of protein homotetramer biosynthesis|up-regulation of protein homotetramer formation|activation of protein homotetramer formation|positive regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer assembly|activation of protein homotetramer assembly|positive regulation of protein homotetramer assembly|up regulation of protein homotetramerization|activation of protein homotetramerization|up-regulation of protein homotetramer biosynthesis|positive regulation of protein homotetramer formation|up-regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer formation|up-regulation of protein homotetramer assembly|up-regulation of protein homotetramerization|upregulation of protein homotetramer biosynthetic process|upregulation of protein homotetramer biosynthesis http://purl.obolibrary.org/obo/GO_1901095 CHEBI:36267 biolink:ChemicalSubstance molybdenum oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36267 GO:1901096 biolink:BiologicalProcess regulation of autophagosome maturation Any process that modulates the frequency, rate or extent of autophagosome maturation. go-plus.json regulation of amphisome-lysosome fusion|regulation of autolysosome formation|regulation of autophagosome maturation|regulation of autophagic vacuole fusion|regulation of fusion of autophagosome with lysosome|regulation of autophagosome fusion http://purl.obolibrary.org/obo/GO_1901096 GO:1901093 biolink:BiologicalProcess regulation of protein homotetramerization Any process that modulates the frequency, rate or extent of protein homotetramerization. go-plus.json regulation of protein homotetramer biosynthetic process|regulation of protein homotetramer biosynthesis|regulation of protein homotetramer assembly|regulation of protein homotetramer formation http://purl.obolibrary.org/obo/GO_1901093 GO:0012501 biolink:BiologicalProcess programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. Wikipedia:Programmed_cell_death go-plus.json non-apoptotic programmed cell death|caspase-independent cell death|caspase-independent apoptosis|RCD|regulated cell death|PCD|nonapoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0012501 GO:1901094 biolink:BiologicalProcess negative regulation of protein homotetramerization Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization. go-plus.json down regulation of protein homotetramer biosynthetic process|down regulation of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthetic process|down regulation of protein homotetramer assembly|down regulation of protein homotetramerization|downregulation of protein homotetramer assembly|downregulation of protein homotetramerization|down-regulation of protein homotetramer biosynthesis|negative regulation of protein homotetramer biosynthetic process|negative regulation of protein homotetramer biosynthesis|down-regulation of protein homotetramer biosynthetic process|negative regulation of protein homotetramer formation|down-regulation of protein homotetramer formation|negative regulation of protein homotetramer assembly|down-regulation of protein homotetramer assembly|inhibition of protein homotetramer biosynthesis|inhibition of protein homotetramer biosynthetic process|down-regulation of protein homotetramerization|downregulation of protein homotetramer formation|inhibition of protein homotetramer assembly|inhibition of protein homotetramerization|down regulation of protein homotetramer formation|inhibition of protein homotetramer formation http://purl.obolibrary.org/obo/GO_1901094 GO:0012502 biolink:BiologicalProcess induction of programmed cell death A process which directly activates any of the steps required for programmed cell death. go-plus.json induction of nonapoptotic programmed cell death|induction of non-apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0012502 GO:1901091 biolink:BiologicalProcess negative regulation of protein tetramerization Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization. go-plus.json downregulation of protein tetramer assembly|downregulation of protein tetramer formation|downregulation of protein tetramerization|down-regulation of protein tetramer biosynthesis|down-regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer biosynthesis|down regulation of protein tetramer formation|inhibition of protein tetramer formation|inhibition of protein tetramer biosynthesis|inhibition of protein tetramer biosynthetic process|down-regulation of protein tetramer assembly|negative regulation of protein tetramer assembly|down-regulation of protein tetramerization|inhibition of protein tetramer assembly|inhibition of protein tetramerization|down regulation of protein tetramer biosynthesis|down regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer formation|down-regulation of protein tetramer formation|downregulation of protein tetramer biosynthetic process|downregulation of protein tetramer biosynthesis|down regulation of protein tetramer assembly|down regulation of protein tetramerization http://purl.obolibrary.org/obo/GO_1901091 CHEBI:9209 biolink:ChemicalSubstance soyasapogenol B go-plus.json http://purl.obolibrary.org/obo/CHEBI_9209 chebi_ph7_3 GO:1901092 biolink:BiologicalProcess positive regulation of protein tetramerization Any process that activates or increases the frequency, rate or extent of protein tetramerization. go-plus.json up regulation of protein tetramer assembly|activation of protein tetramer assembly|positive regulation of protein tetramer assembly|up regulation of protein tetramerization|activation of protein tetramerization|upregulation of protein tetramer formation|up-regulation of protein tetramer biosynthesis|up-regulation of protein tetramer biosynthetic process|up-regulation of protein tetramer assembly|up-regulation of protein tetramer formation|up-regulation of protein tetramerization|activation of protein tetramer formation|upregulation of protein tetramer biosynthesis|upregulation of protein tetramer biosynthetic process|upregulation of protein tetramer assembly|upregulation of protein tetramerization|positive regulation of protein tetramer formation|up regulation of protein tetramer biosynthesis|up regulation of protein tetramer biosynthetic process|up regulation of protein tetramer formation|positive regulation of protein tetramer biosynthesis|activation of protein tetramer biosynthesis|activation of protein tetramer biosynthetic process|positive regulation of protein tetramer biosynthetic process http://purl.obolibrary.org/obo/GO_1901092 CHEBI:36261 biolink:ChemicalSubstance taurodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36261 chebi_ph7_3 CHEBI:36262 biolink:ChemicalSubstance molybdenum oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36262 GO:1901090 biolink:BiologicalProcess regulation of protein tetramerization Any process that modulates the frequency, rate or extent of protein tetramerization. go-plus.json regulation of protein tetramer formation|regulation of protein tetramer biosynthesis|regulation of protein tetramer biosynthetic process|regulation of protein tetramer assembly http://purl.obolibrary.org/obo/GO_1901090 CHEBI:36260 biolink:ChemicalSubstance monohydroxy-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36260 CHEBI:36265 biolink:ChemicalSubstance transition element oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36265 CHEBI:36263 biolink:ChemicalSubstance hydrogenmolybdate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36263 CHEBI:36264 biolink:ChemicalSubstance molybdate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36264 chebi_ph7_3 CHEBI:75800 biolink:ChemicalSubstance (2'->5')-dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_75800 CHEBI:36280 biolink:ChemicalSubstance oct-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36280 CHEBI:131528 biolink:ChemicalSubstance aurachin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_131528 GO:1901099 biolink:BiologicalProcess negative regulation of signal transduction in absence of ligand Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand. go-plus.json down regulation of basal signaling|down-regulation of non-classical signal transduction|negative regulation of non-classical signal transduction|downregulation of basal signaling|down-regulation of signal transduction in absence of ligand|down-regulation of basal signaling|down regulation of signal transduction in absence of agonist|downregulation of signal transduction in absence of agonist|down regulation of non-classical signal transduction|downregulation of signal transduction in absence of ligand|downregulation of non-classical signal transduction|down regulation of signal transduction in absence of ligand|down-regulation of signal transduction in absence of agonist|negative regulation of signal transduction in absence of agonist|inhibition of signal transduction in absence of ligand http://purl.obolibrary.org/obo/GO_1901099 CHEBI:36278 biolink:ChemicalSubstance cholanic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_36278 CHEBI:36279 biolink:ChemicalSubstance oct-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36279 GO:0012510 biolink:CellularComponent trans-Golgi network transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell. go-plus.json trans-Golgi network constitutive secretory pathway transport vesicle membrane|TGN transport vesicle membrane http://purl.obolibrary.org/obo/GO_0012510 CHEBI:131522 biolink:ChemicalSubstance dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_131522 GO:0012511 biolink:CellularComponent monolayer-surrounded lipid storage body A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins. Wikipedia:Oil_body go-plus.json oleosome|oilbody|oil body|spherosome http://purl.obolibrary.org/obo/GO_0012511 CHEBI:36272 biolink:ChemicalSubstance tungstic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36272 CHEBI:36270 biolink:ChemicalSubstance tungsten oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36270 CHEBI:36271 biolink:ChemicalSubstance hydrogentungstate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36271 CHEBI:9211 biolink:ChemicalSubstance soyasaponin I go-plus.json http://purl.obolibrary.org/obo/CHEBI_9211 CHEBI:36274 biolink:ChemicalSubstance glycochenodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36274 CHEBI:36275 biolink:ChemicalSubstance HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_36275 CHEBI:75819 biolink:ChemicalSubstance 8-oxo-ETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_75819 CHEBI:36248 biolink:ChemicalSubstance 5beta-cholanic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_36248 CHEBI:36246 biolink:ChemicalSubstance 5alpha-cholanic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_36246 CHEBI:36249 biolink:ChemicalSubstance bile acid conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36249 CHEBI:36240 biolink:ChemicalSubstance 3alpha,7alpha,12beta-trihydroxy-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36240 CHEBI:36243 biolink:ChemicalSubstance propanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_36243 chebi_ph7_3 CHEBI:36244 biolink:ChemicalSubstance dicarboxylic acid monoester go-plus.json http://purl.obolibrary.org/obo/CHEBI_36244 CHEBI:36241 biolink:ChemicalSubstance 3,4-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36241 chebi_ph7_3 CHEBI:36242 biolink:ChemicalSubstance 3-(4-hydroxyphenyl)pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36242 chebi_ph7_3 CHEBI:75822 biolink:ChemicalSubstance (8S,9S)-epoxy-(10R)-hydroxyicosa-(5Z,11Z,14Z)-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75822 CHEBI:51877 biolink:ChemicalSubstance bisindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_51877 CHEBI:51879 biolink:ChemicalSubstance bisindole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51879 CHEBI:75824 biolink:ChemicalSubstance 2,3-dioleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75824 chebi_ph7_3 CHEBI:75825 biolink:ChemicalSubstance (7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75825 CHEBI:36258 biolink:ChemicalSubstance but-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36258 chebi_ph7_3 CHEBI:36259 biolink:ChemicalSubstance taurolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36259 CHEBI:36257 biolink:ChemicalSubstance taurocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36257 chebi_ph7_3 CHEBI:36255 biolink:ChemicalSubstance bile acid glycine conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36255 CHEBI:36252 biolink:ChemicalSubstance glycochenodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36252 chebi_ph7_3 GO:0061440 biolink:BiologicalProcess kidney vasculature development The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061440 GO:0061441 biolink:BiologicalProcess renal artery morphogenesis The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. go-plus.json http://purl.obolibrary.org/obo/GO_0061441 GO:0061442 biolink:BiologicalProcess cardiac muscle cell fate determination The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0061442 GO:0036475 biolink:BiologicalProcess neuron death in response to oxidative stress Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus. go-plus.json oxidative stress-induced neuron death|neuronal cell death in response to oxidative stress http://purl.obolibrary.org/obo/GO_0036475 GO:0036476 biolink:BiologicalProcess neuron death in response to hydrogen peroxide Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2). go-plus.json neuron death in response to H2O2|neuronal cell death in response to hydrogen peroxide|hydrogen peroxide-induced neuron death http://purl.obolibrary.org/obo/GO_0036476 GO:0061443 biolink:BiologicalProcess endocardial cushion cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061443 GO:0061444 biolink:BiologicalProcess endocardial cushion cell development The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0061444 GO:0036477 biolink:CellularComponent somatodendritic compartment The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. go-plus.json http://purl.obolibrary.org/obo/GO_0036477 GO:0036478 biolink:MolecularActivity L-dopa decarboxylase activator activity Interacts with and increases L-dopa decarboxylase activity. go-plus.json DDC activator activity http://purl.obolibrary.org/obo/GO_0036478 GO:0061445 biolink:BiologicalProcess endocardial cushion cell fate commitment The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061445 GO:0036479 biolink:MolecularActivity peroxidase inhibitor activity Binds to and stops, prevents or reduces the activity of peroxidase. go-plus.json http://purl.obolibrary.org/obo/GO_0036479 GO:0061446 biolink:BiologicalProcess endocardial cushion cell fate determination The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0061446 GO:0061447 biolink:BiologicalProcess endocardial cushion cell fate specification The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. go-plus.json http://purl.obolibrary.org/obo/GO_0061447 GO:0061448 biolink:BiologicalProcess connective tissue development The progression of a connective tissue over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061448 GO:0061449 biolink:BiologicalProcess olfactory bulb tufted cell development The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061449 GO:0036470 biolink:MolecularActivity tyrosine 3-monooxygenase activator activity Interacts with and increases tyrosine 3-monooxygenase (tyrosine hydroxylase) activity. go-plus.json tyrosine hydroxylase activator activity|TH activator activity http://purl.obolibrary.org/obo/GO_0036470 GO:0036471 biolink:BiologicalProcess cellular response to glyoxal Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036471 GO:0036472 biolink:BiologicalProcess suppression by virus of host protein-protein interaction Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins. go-plus.json suppression by virus of host protein:protein interaction|suppression by virus of host protein interaction|suppression by virus of host protein:protein binding|suppression by virus of host protein binding http://purl.obolibrary.org/obo/GO_0036472 GO:0036473 biolink:BiologicalProcess cell death in response to oxidative stress Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0036473 GO:0036474 biolink:BiologicalProcess cell death in response to hydrogen peroxide Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2). go-plus.json cell death in response to H2O2|hydrogen peroxide-mediated cell death http://purl.obolibrary.org/obo/GO_0036474 CHEBI:85195 biolink:ChemicalSubstance 9,10-epoxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85195 chebi_ph7_3 CHEBI:85197 biolink:ChemicalSubstance 9,10-dihydroxystearate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85197 chebi_ph7_3 CHEBI:85198 biolink:ChemicalSubstance N-arachidonoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85198 chebi_ph7_3 CHEBI:85199 biolink:ChemicalSubstance N-icosenoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85199 chebi_ph7_3 GO:0061430 biolink:BiologicalProcess bone trabecula morphogenesis The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod. go-plus.json http://purl.obolibrary.org/obo/GO_0061430 GO:0061431 biolink:BiologicalProcess cellular response to methionine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061431 GO:0036464 biolink:CellularComponent cytoplasmic ribonucleoprotein granule A ribonucleoprotein granule located in the cytoplasm. go-plus.json Staufen granule http://purl.obolibrary.org/obo/GO_0036464 GO:0036465 biolink:BiologicalProcess synaptic vesicle recycling The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. go-plus.json kiss-and-stay synaptic vesicle recycling|kiss-and-run synaptic vesicle recycling http://purl.obolibrary.org/obo/GO_0036465 GO:0061432 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to methionine OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061432 GO:0036466 biolink:BiologicalProcess synaptic vesicle recycling via endosome Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate. go-plus.json recycling endosome localization within postsynapse http://purl.obolibrary.org/obo/GO_0036466 goslim_synapse GO:0061433 biolink:BiologicalProcess cellular response to caloric restriction Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake. go-plus.json http://purl.obolibrary.org/obo/GO_0061433 GO:0061434 biolink:BiologicalProcess obsolete regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061434 GO:0036467 biolink:MolecularActivity 5-hydroxy-L-tryptophan decarboxylase activity Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin. RHEA:18533 go-plus.json 5-hydroxytryptophan decarboxylase activity http://purl.obolibrary.org/obo/GO_0036467 GO:0061435 biolink:BiologicalProcess positive regulation of transcription from a mobile element promoter Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0061435 GO:0036468 biolink:MolecularActivity L-dopa decarboxylase activity Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine. RHEA:12272 go-plus.json DDC activity|4-dihydroxyl-L-phenylalanine decarboxylase activity|DOPA decarboxylase activity http://purl.obolibrary.org/obo/GO_0036468 GO:0061436 biolink:BiologicalProcess establishment of skin barrier Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability. go-plus.json skin barrier development|epithelial barrier development|establishment of epithelial barrier http://purl.obolibrary.org/obo/GO_0061436 GO:0036469 biolink:MolecularActivity L-tryptophan decarboxylase activity Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine. RHEA:30339|EC:4.1.1.105 go-plus.json L-tryptophan decarboxylase activity http://purl.obolibrary.org/obo/GO_0036469 GO:0061437 biolink:BiologicalProcess renal system vasculature development The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061437 GO:0061438 biolink:BiologicalProcess renal system vasculature morphogenesis The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form. go-plus.json http://purl.obolibrary.org/obo/GO_0061438 GO:0061439 biolink:BiologicalProcess kidney vasculature morphogenesis The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form. go-plus.json http://purl.obolibrary.org/obo/GO_0061439 GO:0036460 biolink:BiologicalProcess cellular response to cell envelope stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope. go-plus.json envelope stress response http://purl.obolibrary.org/obo/GO_0036460 GO:0036461 biolink:MolecularActivity BLOC-2 complex binding Binding to a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. go-plus.json http://purl.obolibrary.org/obo/GO_0036461 GO:0036462 biolink:BiologicalProcess TRAIL-activated apoptotic signaling pathway An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface. go-plus.json TRAIL-activated extrinsic apoptotic signaling pathway|TRAIL-induced apoptotic signaling pathway|tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0036462 GO:0036463 biolink:MolecularActivity TRAIL receptor activity Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death. go-plus.json tumor necrosis factor-related apoptosis-inducing ligand receptor http://purl.obolibrary.org/obo/GO_0036463 GO:2000005 biolink:BiologicalProcess negative regulation of metanephric S-shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000005 GO:2000006 biolink:BiologicalProcess regulation of metanephric comma-shaped body morphogenesis Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000006 GO:2000007 biolink:BiologicalProcess negative regulation of metanephric comma-shaped body morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000007 GO:2000008 biolink:BiologicalProcess regulation of protein localization to cell surface Any process that modulates the frequency, rate or extent of protein localization to the cell surface. go-plus.json regulation of protein localisation at cell surface|regulation of protein localization at cell surface http://purl.obolibrary.org/obo/GO_2000008 GO:2000009 biolink:BiologicalProcess negative regulation of protein localization to cell surface Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface. go-plus.json negative regulation of protein localisation at cell surface|negative regulation of protein localization at cell surface http://purl.obolibrary.org/obo/GO_2000009 GO:0061460 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061460 GO:0061461 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061461 GO:0061462 biolink:BiologicalProcess protein localization to lysosome A process in which a protein is transported to, or maintained in, a location within a lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061462 GO:0061463 biolink:MolecularActivity O-acetyl-ADP-ribose deacetylase activity Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate. go-plus.json http://purl.obolibrary.org/obo/GO_0061463 GO:0036453 biolink:BiologicalProcess transitive RNA interference An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence. go-plus.json transitive RNAi http://purl.obolibrary.org/obo/GO_0036453 GO:0061464 biolink:CellularComponent obsolete plasma membrane part of cell-substrate junction OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell-substrate junction. go-plus.json http://purl.obolibrary.org/obo/GO_0061464 GO:0061465 biolink:CellularComponent obsolete plasma membrane part of hemidesmosome OBSOLETE. The part of the plasma membrane that contributes to the structure of a hemidesmosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061465 GO:0036454 biolink:CellularComponent growth factor complex A protein complex that has growth factor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0036454 GO:0036455 biolink:MolecularActivity iron-sulfur transferase activity Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor). Reactome:R-HSA-2564828 go-plus.json Fe-S transferase activity http://purl.obolibrary.org/obo/GO_0036455 GO:0061466 biolink:CellularComponent obsolete plasma membrane part of cell junction OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell junction. go-plus.json http://purl.obolibrary.org/obo/GO_0061466 GO:0036456 biolink:MolecularActivity L-methionine-(S)-S-oxide reductase activity Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O. RHEA:19995 go-plus.json http://purl.obolibrary.org/obo/GO_0036456 GO:0061467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061467 GO:0061468 biolink:CellularComponent karyomere A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0061468 GO:0036457 biolink:CellularComponent keratohyalin granule A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0036457 GO:2000001 biolink:BiologicalProcess regulation of DNA damage checkpoint Any process that modulates the frequency, rate or extent of a DNA damage checkpoint. go-plus.json regulation of DNA damage response, signal transduction resulting in cell cycle arrest http://purl.obolibrary.org/obo/GO_2000001 GO:0036458 biolink:MolecularActivity hepatocyte growth factor binding Binding to a hepatocyte growth factor. go-plus.json HGF binding http://purl.obolibrary.org/obo/GO_0036458 GO:2000002 biolink:BiologicalProcess negative regulation of DNA damage checkpoint Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint. go-plus.json negative regulation of DNA damage response, signal transduction resulting in cell cycle arrest http://purl.obolibrary.org/obo/GO_2000002 GO:0061469 biolink:BiologicalProcess regulation of type B pancreatic cell proliferation Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0061469 GO:2000003 biolink:BiologicalProcess positive regulation of DNA damage checkpoint Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint. go-plus.json positive regulation of DNA damage response, signal transduction resulting in cell cycle arrest http://purl.obolibrary.org/obo/GO_2000003 GO:0036459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036459 GO:2000004 biolink:BiologicalProcess regulation of metanephric S-shaped body morphogenesis Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000004 GO:0036450 biolink:BiologicalProcess polyuridylation-dependent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end. go-plus.json uridylation-dependent decapping of nuclear-transcribed mRNA http://purl.obolibrary.org/obo/GO_0036450 GO:0036451 biolink:BiologicalProcess cap mRNA methylation Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0036451 GO:0036452 biolink:CellularComponent ESCRT complex An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes. Wikipedia:ESCRT go-plus.json endosomal sorting complex required for transport http://purl.obolibrary.org/obo/GO_0036452 GO:2000016 biolink:BiologicalProcess negative regulation of determination of dorsal identity Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity. go-plus.json negative regulation of determination of adaxial identity http://purl.obolibrary.org/obo/GO_2000016 GO:2000017 biolink:BiologicalProcess positive regulation of determination of dorsal identity Any process that activates or increases the frequency, rate or extent of determination of dorsal identity. go-plus.json positive regulation of determination of adaxial identity http://purl.obolibrary.org/obo/GO_2000017 GO:2000018 biolink:BiologicalProcess regulation of male gonad development Any process that modulates the frequency, rate or extent of male gonad development. go-plus.json regulation of testicular development|regulation of testis development http://purl.obolibrary.org/obo/GO_2000018 GO:2000019 biolink:BiologicalProcess negative regulation of male gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development. go-plus.json negative regulation of testis development|negative regulation of testicular development http://purl.obolibrary.org/obo/GO_2000019 GO:0061450 biolink:BiologicalProcess trophoblast cell migration Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. go-plus.json http://purl.obolibrary.org/obo/GO_0061450 GO:0061451 biolink:BiologicalProcess retrotrapezoid nucleus development The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration. go-plus.json http://purl.obolibrary.org/obo/GO_0061451 GO:0061452 biolink:BiologicalProcess retrotrapezoid nucleus neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0061452 GO:0036442 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036442 GO:0061453 biolink:BiologicalProcess interstitial cell of Cajal differentiation The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction. go-plus.json ICC differentiation http://purl.obolibrary.org/obo/GO_0061453 GO:0061454 biolink:BiologicalProcess release of sequestered calcium ion into cytosol by Golgi The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol. go-plus.json Golgi calcium ion export http://purl.obolibrary.org/obo/GO_0061454 GO:0036443 biolink:MolecularActivity dermatan 6-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate. KEGG_REACTION:R07288 go-plus.json http://purl.obolibrary.org/obo/GO_0036443 GO:2000010 biolink:BiologicalProcess positive regulation of protein localization to cell surface Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface. go-plus.json positive regulation of protein localisation at cell surface|positive regulation of protein localization at cell surface http://purl.obolibrary.org/obo/GO_2000010 GO:0061455 biolink:CellularComponent integral component of muscle cell projection membrane The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to muscle cell projection membrane http://purl.obolibrary.org/obo/GO_0061455 GO:0036444 biolink:BiologicalProcess calcium import into the mitochondrion A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix. go-plus.json mitochondrial calcium ion import|mitochondrial calcium uptake|calcium ion transmembrane import into mitochondrion|calcium ion import into mitochondrion http://purl.obolibrary.org/obo/GO_0036444 GO:0061456 biolink:BiologicalProcess mesenchymal stem cell migration involved in uteric bud morphogenesis The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061456 GO:2000011 biolink:BiologicalProcess regulation of adaxial/abaxial pattern formation Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation. go-plus.json regulation of adaxial/abaxial pattern specification http://purl.obolibrary.org/obo/GO_2000011 GO:0036445 biolink:BiologicalProcess neuronal stem cell division The self-renewing division of a neuronal stem cell. go-plus.json NSC division http://purl.obolibrary.org/obo/GO_0036445 GO:0061457 biolink:BiologicalProcess mesonephric cell migration involved in male gonad development The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development. go-plus.json http://purl.obolibrary.org/obo/GO_0061457 GO:0036446 biolink:BiologicalProcess myofibroblast differentiation The process in which an undifferentiated cell acquires the features of a myofibroblast cell. go-plus.json myofibroblast cell differentiation http://purl.obolibrary.org/obo/GO_0036446 GO:2000012 biolink:BiologicalProcess regulation of auxin polar transport Any process that modulates the frequency, rate or extent of auxin polar transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000012 GO:2000013 biolink:BiologicalProcess regulation of arginine biosynthetic process via ornithine Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine. go-plus.json regulation of arginine formation via ornithine|regulation of arginine anabolism via ornithine|regulation of arginine synthesis via ornithine http://purl.obolibrary.org/obo/GO_2000013 GO:0061458 biolink:BiologicalProcess reproductive system development The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0061458 GO:0036447 biolink:BiologicalProcess cellular response to sugar-phosphate stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate. go-plus.json cellular response to presence of non-metabolizable sugars http://purl.obolibrary.org/obo/GO_0036447 GO:0061459 biolink:MolecularActivity L-arginine transmembrane transporter activity Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane. go-plus.json ATP-dependent L-arginine transmembrane transporter activity|arginine porter activity|ATPase-coupled L-arginine transmembrane transporter activity|L-arginine-importing ATPase activity|arginine-importing ATPase activity http://purl.obolibrary.org/obo/GO_0061459 GO:0036448 biolink:BiologicalProcess cellular response to glucose-phosphate stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0036448 GO:2000014 biolink:BiologicalProcess regulation of endosperm development Any process that modulates the frequency, rate or extent of endosperm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000014 GO:2000015 biolink:BiologicalProcess regulation of determination of dorsal identity Any process that modulates the frequency, rate or extent of determination of dorsal identity. go-plus.json regulation of determination of adaxial identity http://purl.obolibrary.org/obo/GO_2000015 GO:0036449 biolink:CellularComponent microtubule minus-end The end of a microtubule that does not preferentially grow (polymerize). go-plus.json microtubule minus end http://purl.obolibrary.org/obo/GO_0036449 GO:0036440 biolink:MolecularActivity citrate synthase activity Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA. RHEA:16845|KEGG_REACTION:R00351 go-plus.json http://purl.obolibrary.org/obo/GO_0036440 GO:0036441 biolink:MolecularActivity 2-dehydropantolactone reductase activity Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. KEGG_REACTION:R03155|RHEA:18981 go-plus.json http://purl.obolibrary.org/obo/GO_0036441 GO:1901008 biolink:BiologicalProcess (S)-scoulerine catabolic process The chemical reactions and pathways resulting in the breakdown of (S)-scoulerine. go-plus.json (S)-scoulerine breakdown|(S)-scoulerine catabolism|(S)-scoulerine degradation http://purl.obolibrary.org/obo/GO_1901008 GO:1901009 biolink:BiologicalProcess (S)-scoulerine biosynthetic process The chemical reactions and pathways resulting in the formation of (S)-scoulerine. go-plus.json (S)-scoulerine anabolism|(S)-scoulerine biosynthesis|(S)-scoulerine synthesis|(S)-scoulerine formation http://purl.obolibrary.org/obo/GO_1901009 GO:1901006 biolink:BiologicalProcess ubiquinone-6 biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone-6. go-plus.json ubiquinone-6 biosynthesis|ubiquinone-6 anabolism|ubiquinone-6 synthesis|ubiquinone-6 formation http://purl.obolibrary.org/obo/GO_1901006 GO:0036439 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0036439 GO:1901007 biolink:BiologicalProcess (S)-scoulerine metabolic process The chemical reactions and pathways involving (S)-scoulerine. go-plus.json (S)-scoulerine metabolism http://purl.obolibrary.org/obo/GO_1901007 GO:1901004 biolink:BiologicalProcess ubiquinone-6 metabolic process The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2. go-plus.json coenzyme Q6 metabolism|ubiquinone-6 metabolism|coenzyme Q6 metabolic process http://purl.obolibrary.org/obo/GO_1901004 GO:0061480 biolink:BiologicalProcess response to asparaginase Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061480 GO:1901005 biolink:BiologicalProcess ubiquinone-6 catabolic process The chemical reactions and pathways resulting in the breakdown of ubiquinone-6. go-plus.json ubiquinone-6 breakdown|ubiquinone-6 catabolism|ubiquinone-6 degradation http://purl.obolibrary.org/obo/GO_1901005 GO:0061481 biolink:BiologicalProcess response to TNF agonist Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061481 GO:1901002 biolink:BiologicalProcess positive regulation of response to salt stress Any process that activates or increases the frequency, rate or extent of response to salt stress. go-plus.json positive regulation of response to ionic osmotic stress|upregulation of response to salt stress|upregulation of salinity response|up regulation of response to ionic osmotic stress|up regulation of response to salt stress|activation of response to salt stress|up regulation of salinity response|upregulation of response to ionic osmotic stress|positive regulation of salinity response|activation of salinity response|up-regulation of response to ionic osmotic stress|up-regulation of response to salt stress|up-regulation of salinity response|activation of response to ionic osmotic stress http://purl.obolibrary.org/obo/GO_1901002 GO:0061482 biolink:BiologicalProcess response to irinotecan Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061482 GO:1901003 biolink:BiologicalProcess negative regulation of fermentation Any process that stops, prevents or reduces the frequency, rate or extent of fermentation. go-plus.json down-regulation of fermentation|downregulation of fermentation|down regulation of fermentation|inhibition of fermentation http://purl.obolibrary.org/obo/GO_1901003 GO:0061483 biolink:MolecularActivity sulfinylpropanyl adenylate synthase Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate. go-plus.json SPA synthase http://purl.obolibrary.org/obo/GO_0061483 GO:1901000 biolink:BiologicalProcess regulation of response to salt stress Any process that modulates the frequency, rate or extent of response to salt stress. go-plus.json regulation of response to ionic osmotic stress|regulation of salinity response http://purl.obolibrary.org/obo/GO_1901000 GO:0061484 biolink:BiologicalProcess hematopoietic stem cell homeostasis Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061484 GO:1901001 biolink:BiologicalProcess negative regulation of response to salt stress Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress. go-plus.json inhibition of salinity response|down regulation of response to salt stress|downregulation of response to ionic osmotic stress|down regulation of salinity response|downregulation of response to salt stress|down regulation of response to ionic osmotic stress|downregulation of salinity response|down-regulation of response to salt stress|inhibition of response to ionic osmotic stress|negative regulation of salinity response|down-regulation of salinity response|inhibition of response to salt stress|negative regulation of response to ionic osmotic stress|down-regulation of response to ionic osmotic stress http://purl.obolibrary.org/obo/GO_1901001 GO:0061485 biolink:BiologicalProcess memory T cell proliferation The expansion of a memory T cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0061485 GO:0036431 biolink:MolecularActivity dCMP kinase activity Catalysis of the reaction: ATP + dCMP = ADP + dCDP. RHEA:25094|MetaCyc:RXN-11831|MetaCyc:RXN-7913|KEGG_REACTION:R01665 go-plus.json ATP:dCMP phosphotransferase activity http://purl.obolibrary.org/obo/GO_0036431 GO:0061486 biolink:MolecularActivity high-affinity fructose transmembrane transporter activity Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity fructose transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0061486 CHEBI:131593 biolink:ChemicalSubstance 3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131593 GO:0036432 biolink:MolecularActivity all-trans undecaprenol kinase activity Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+. RHEA:23752 go-plus.json http://purl.obolibrary.org/obo/GO_0036432 GO:1901010 biolink:BiologicalProcess (S)-reticuline metabolic process The chemical reactions and pathways involving (S)-reticuline. go-plus.json (S)-reticuline metabolism http://purl.obolibrary.org/obo/GO_1901010 GO:0061487 biolink:BiologicalProcess obsolete DNA replication initiation from late origin OBSOLETE. The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase. go-plus.json late replication origin firing http://purl.obolibrary.org/obo/GO_0061487 GO:0036433 biolink:MolecularActivity di-trans, poly-cis-undecaprenol kinase activity Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+. RHEA:28122|MetaCyc:UNDECAPRENOL-KINASE-RXN|KEGG_REACTION:R05626 go-plus.json ditrans,polycis-undecaprenol kinase activity http://purl.obolibrary.org/obo/GO_0036433 GO:0061488 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061488 GO:0036434 biolink:MolecularActivity nitronate monooxygenase (FMN-linked) activity Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite. KEGG_REACTION:R00025|RHEA:26458 go-plus.json http://purl.obolibrary.org/obo/GO_0036434 GO:0061489 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061489 CHEBI:131596 biolink:ChemicalSubstance CMP-3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131596 GO:0036435 biolink:MolecularActivity K48-linked polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein. Reactome:R-HSA-5683077 go-plus.json http://purl.obolibrary.org/obo/GO_0036435 GO:0036436 biolink:CellularComponent Isw1a complex An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p. go-plus.json http://purl.obolibrary.org/obo/GO_0036436 GO:0036437 biolink:CellularComponent Isw1b complex An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p. go-plus.json http://purl.obolibrary.org/obo/GO_0036437 GO:0036438 biolink:BiologicalProcess maintenance of lens transparency A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina. go-plus.json preservation of lens transparency|maintenance of ocular lens transparency http://purl.obolibrary.org/obo/GO_0036438 CHEBI:131591 biolink:ChemicalSubstance C18-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131591 GO:0036430 biolink:MolecularActivity CMP kinase activity Catalysis of the reaction: ATP + CMP = ADP + CDP. MetaCyc:RXN-11832|KEGG_REACTION:R00512|RHEA:11600 go-plus.json http://purl.obolibrary.org/obo/GO_0036430 GO:1901019 biolink:BiologicalProcess regulation of calcium ion transmembrane transporter activity Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_1901019 GO:1901017 biolink:BiologicalProcess negative regulation of potassium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity. go-plus.json downregulation of potassium transporter activity|downregulation of potassium ion transmembrane transporter activity|down regulation of potassium transporter activity|down regulation of potassium ion transmembrane transporter activity|inhibition of potassium ion transmembrane transporter activity|inhibition of potassium transporter activity|negative regulation of potassium transporter activity|down-regulation of potassium transporter activity|down-regulation of potassium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901017 GO:0036428 biolink:MolecularActivity adenosylcobinamide kinase (GTP-specific) activity Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+. MetaCyc:RXN-14063|KEGG_REACTION:R06558|RHEA:15765 go-plus.json http://purl.obolibrary.org/obo/GO_0036428 GO:1901018 biolink:BiologicalProcess positive regulation of potassium ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity. go-plus.json positive regulation of potassium transporter activity|up regulation of potassium transporter activity|up regulation of potassium ion transmembrane transporter activity|upregulation of potassium transporter activity|upregulation of potassium ion transmembrane transporter activity|up-regulation of potassium transporter activity|up-regulation of potassium ion transmembrane transporter activity|activation of potassium ion transmembrane transporter activity|activation of potassium transporter activity http://purl.obolibrary.org/obo/GO_1901018 GO:0036429 biolink:MolecularActivity adenosylcobinamide kinase (ATP-specific) activity Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+. MetaCyc:COBINAMIDEKIN-RXN|RHEA:15769|KEGG_REACTION:R05221 go-plus.json http://purl.obolibrary.org/obo/GO_0036429 GO:1901015 biolink:BiologicalProcess 3alpha(S)-strictosidine biosynthetic process The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine. go-plus.json 3alpha(S)-strictosidine anabolism|3alpha(S)-strictosidine synthesis|3alpha(S)-strictosidine formation|3alpha(S)-strictosidine biosynthesis http://purl.obolibrary.org/obo/GO_1901015 GO:1901016 biolink:BiologicalProcess regulation of potassium ion transmembrane transporter activity Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity. go-plus.json regulation of potassium transporter activity http://purl.obolibrary.org/obo/GO_1901016 GO:0061470 biolink:BiologicalProcess T follicular helper cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell. go-plus.json T-helper follicular cell differentiation http://purl.obolibrary.org/obo/GO_0061470 GO:0061471 biolink:BiologicalProcess karyomere assembly The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0061471 GO:1901013 biolink:BiologicalProcess 3alpha(S)-strictosidine metabolic process The chemical reactions and pathways involving 3alpha(S)-strictosidine. go-plus.json 3alpha(S)-strictosidine metabolism http://purl.obolibrary.org/obo/GO_1901013 GO:0061472 biolink:BiologicalProcess karyomere membrane fusion Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0061472 GO:1901014 biolink:BiologicalProcess 3alpha(S)-strictosidine catabolic process The chemical reactions and pathways resulting in the breakdown of 3alpha(S)-strictosidine. go-plus.json 3alpha(S)-strictosidine catabolism|3alpha(S)-strictosidine degradation|3alpha(S)-strictosidine breakdown http://purl.obolibrary.org/obo/GO_1901014 GO:1901011 biolink:BiologicalProcess (S)-reticuline catabolic process The chemical reactions and pathways resulting in the breakdown of (S)-reticuline. go-plus.json (S)-reticuline catabolism|(S)-reticuline degradation|(S)-reticuline breakdown http://purl.obolibrary.org/obo/GO_1901011 GO:0061473 biolink:MolecularActivity murein tripeptide carboxypeptidase activity Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate. go-plus.json http://purl.obolibrary.org/obo/GO_0061473 GO:1901012 biolink:BiologicalProcess (S)-reticuline biosynthetic process The chemical reactions and pathways resulting in the formation of (S)-reticuline. go-plus.json (S)-reticuline anabolism|(S)-reticuline synthesis|(S)-reticuline biosynthesis|(S)-reticuline formation http://purl.obolibrary.org/obo/GO_1901012 GO:0061474 biolink:CellularComponent phagolysosome membrane The lipid bilayer surrounding a phagolysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061474 GO:1901020 biolink:BiologicalProcess negative regulation of calcium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity. go-plus.json down-regulation of calcium ion transmembrane transporter activity|downregulation of calcium ion transmembrane transporter activity|down regulation of calcium ion transmembrane transporter activity|inhibition of calcium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901020 GO:0036420 biolink:CellularComponent extrinsic component of mycolate outer membrane The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to MOM|extrinsic to mycomembrane|extrinsic to mycolate outer membrane http://purl.obolibrary.org/obo/GO_0036420 GO:0061475 biolink:BiologicalProcess cytosolic valyl-tRNA aminoacylation The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0061475 NCBITaxon:554915 biolink:OrganismalEntity Amoebozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_554915 GO:0061476 biolink:BiologicalProcess response to anticoagulant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061476 GO:1901021 biolink:BiologicalProcess positive regulation of calcium ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity. go-plus.json up regulation of calcium ion transmembrane transporter activity|upregulation of calcium ion transmembrane transporter activity|up-regulation of calcium ion transmembrane transporter activity|activation of calcium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901021 GO:0036421 biolink:CellularComponent extrinsic component of external side of mycolate outer membrane The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to external side of MOM|extrinsic to external side of mycolate outer membrane|extrinsic to external side of mycomembrane http://purl.obolibrary.org/obo/GO_0036421 GO:0036422 biolink:MolecularActivity heptaprenyl diphosphate synthase activity Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate. MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN|EC:2.5.1.30|RHEA:27794 go-plus.json heptaprenyl pyrophosphate synthetase activity|all-trans-heptaprenyl-diphosphate synthase activity|heptaprenyl pyrophosphate synthase activity|HepPP synthase activity http://purl.obolibrary.org/obo/GO_0036422 GO:0061477 biolink:BiologicalProcess response to aromatase inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061477 GO:0061478 biolink:BiologicalProcess response to platelet aggregation inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061478 GO:0036423 biolink:MolecularActivity hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate. MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN|RHEA:27559|EC:2.5.1.83|KEGG_REACTION:R09245 go-plus.json hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity http://purl.obolibrary.org/obo/GO_0036423 GO:0061479 biolink:BiologicalProcess response to reverse transcriptase inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061479 GO:0036424 biolink:MolecularActivity L-phosphoserine phosphatase activity Catalysis of the reaction: O-phospho-L-serine + H2O = L-serine + phosphate, on a free amino acid. MetaCyc:RXN0-5114|MetaCyc:PSERPHOSPHA-RXN|EC:3.1.3.3|KEGG_REACTION:R00582|Reactome:R-HSA-977324|RHEA:21208 go-plus.json O-phosphoserine phosphohydrolase activity|phosphoserine phosphatase activity http://purl.obolibrary.org/obo/GO_0036424 GO:0036425 biolink:MolecularActivity obsolete D-phosphoserine phosphatase activity OBSOLETE. Catalysis of the reaction: O-phospho-D-serine + H2O = L-serine + phosphate, on a free amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0036425 GO:0036426 biolink:MolecularActivity ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP. MetaCyc:2.4.1.54-RXN|KEGG_REACTION:R07257 go-plus.json http://purl.obolibrary.org/obo/GO_0036426 GO:0036427 biolink:MolecularActivity all-trans-undecaprenyl-phosphate mannosyltransferase activity Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP. RHEA:28118 go-plus.json http://purl.obolibrary.org/obo/GO_0036427 OBO:GOCHE_27026 biolink:OntologyClass substance with toxin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_27026 3_STAR OBO:GOCHE_27027 biolink:OntologyClass substance with micronutrient role go-plus.json http://purl.obolibrary.org/obo/GOCHE_27027 3_STAR NCBITaxon:265606 biolink:OrganismalEntity Rhodopirellula baltica go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_265606 GO:0036417 biolink:BiologicalProcess tRNA destabilization Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes. go-plus.json http://purl.obolibrary.org/obo/GO_0036417 GO:1901028 biolink:BiologicalProcess regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. go-plus.json regulation of MOMP|regulation of mitochondrial outer membrane permeabilization http://purl.obolibrary.org/obo/GO_1901028 CHEBI:131579 biolink:ChemicalSubstance pApA go-plus.json http://purl.obolibrary.org/obo/CHEBI_131579 GO:1901029 biolink:BiologicalProcess negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. go-plus.json down regulation of mitochondrial outer membrane permeabilization|downregulation of mitochondrial outer membrane permeabilization|negative regulation of mitochondrial outer membrane permeabilization|down-regulation of MOMP|negative regulation of MOMP|down-regulation of mitochondrial outer membrane permeabilization|inhibition of mitochondrial outer membrane permeabilization|downregulation of MOMP|down regulation of MOMP|inhibition of MOMP http://purl.obolibrary.org/obo/GO_1901029 GO:0036418 biolink:CellularComponent intrinsic component of mycolate outer membrane The component of the mycolate outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to mycomembrane|intrinsic to MOM|intrinsic to mycolate outer membrane http://purl.obolibrary.org/obo/GO_0036418 GO:1901026 biolink:BiologicalProcess ripoptosome assembly involved in necroptotic process The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process. go-plus.json ripoptosome assembly involved in necroptosis http://purl.obolibrary.org/obo/GO_1901026 GO:0036419 biolink:CellularComponent integral component of mycolate outer membrane The component of the mycolate outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to mycolate outer membrane|integral to mycomembrane|integral to MOM http://purl.obolibrary.org/obo/GO_0036419 GO:1901027 biolink:BiologicalProcess dextrin catabolic process The chemical reactions and pathways resulting in the breakdown of dextrin. go-plus.json dextrin degradation|dextrin breakdown|dextrin catabolism http://purl.obolibrary.org/obo/GO_1901027 GO:1901024 biolink:BiologicalProcess 4-hydroxyphenylacetate biosynthetic process The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate. go-plus.json 4-hydroxyphenylacetate synthesis|4-hydroxyphenylacetate formation|4-hydroxyphenylacetate biosynthesis|4-hydroxyphenylacetate anabolism http://purl.obolibrary.org/obo/GO_1901024 GO:1901025 biolink:BiologicalProcess ripoptosome assembly involved in extrinsic apoptotic signaling pathway The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1901025 GO:1901022 biolink:BiologicalProcess 4-hydroxyphenylacetate metabolic process The chemical reactions and pathways involving 4-hydroxyphenylacetate. go-plus.json 4-hydroxyphenylacetate metabolism http://purl.obolibrary.org/obo/GO_1901022 GO:1901023 biolink:BiologicalProcess 4-hydroxyphenylacetate catabolic process The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate. go-plus.json 4-hydroxyphenylacetate degradation|4-hydroxyphenylacetate catabolism|4-hydroxyphenylacetate breakdown http://purl.obolibrary.org/obo/GO_1901023 GO:1901031 biolink:BiologicalProcess regulation of response to reactive oxygen species Any process that modulates the frequency, rate or extent of response to reactive oxygen species. go-plus.json regulation of response to ROI|regulation of response to reactive oxidative species|regulation of response to AOS|regulation of response to reactive oxygen intermediate|regulation of response to ROS|regulation of response to active oxygen species http://purl.obolibrary.org/obo/GO_1901031 GO:0036410 biolink:CellularComponent Mst2 histone acetyltransferase complex A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6. go-plus.json Mst2 H3K14 acetyltransferase complex|Mst2 complex|Mst2 histone H3K14 acetyltransferase complex http://purl.obolibrary.org/obo/GO_0036410 GO:1901032 biolink:BiologicalProcess negative regulation of response to reactive oxygen species Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species. go-plus.json down-regulation of response to reactive oxygen intermediate|negative regulation of response to reactive oxygen intermediate|down regulation of response to ROI|inhibition of response to AOS|down-regulation of response to ROS|negative regulation of response to active oxygen species|down-regulation of response to active oxygen species|negative regulation of response to ROS|downregulation of response to reactive oxidative species|downregulation of response to ROI|down regulation of response to AOS|downregulation of response to reactive oxygen intermediate|down regulation of response to reactive oxidative species|down regulation of response to reactive oxygen species|downregulation of response to AOS|down regulation of response to reactive oxygen intermediate|downregulation of response to reactive oxygen species|down-regulation of response to ROI|negative regulation of response to ROI|inhibition of response to reactive oxidative species|inhibition of response to ROS|inhibition of response to active oxygen species|inhibition of response to reactive oxygen intermediate|negative regulation of response to AOS|down-regulation of response to AOS|down regulation of response to active oxygen species|down-regulation of response to reactive oxygen species|down regulation of response to ROS|inhibition of response to ROI|downregulation of response to ROS|downregulation of response to active oxygen species|negative regulation of response to reactive oxidative species|down-regulation of response to reactive oxidative species|inhibition of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901032 CHEBI:131572 biolink:ChemicalSubstance 3'-L-prolyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_131572 GO:0036411 biolink:CellularComponent H-NS-Cnu complex A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes. go-plus.json http://purl.obolibrary.org/obo/GO_0036411 GO:1901030 biolink:BiologicalProcess positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. go-plus.json upregulation of MOMP|upregulation of mitochondrial outer membrane permeabilization|up-regulation of MOMP|activation of MOMP|positive regulation of mitochondrial outer membrane permeabilization|up regulation of mitochondrial outer membrane permeabilization|activation of mitochondrial outer membrane permeabilization|positive regulation of MOMP|up regulation of MOMP|up-regulation of mitochondrial outer membrane permeabilization http://purl.obolibrary.org/obo/GO_1901030 GO:0036412 biolink:MolecularActivity acetyl-CoA:oxalate CoA-transferase Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA. RHEA:37883 go-plus.json http://purl.obolibrary.org/obo/GO_0036412 GO:0036413 biolink:BiologicalProcess histone H3-R26 citrullination The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3. go-plus.json histone H3 arginine 26 citrullination http://purl.obolibrary.org/obo/GO_0036413 GO:0036414 biolink:BiologicalProcess histone citrullination The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein. go-plus.json histone deimination http://purl.obolibrary.org/obo/GO_0036414 GO:0036415 biolink:BiologicalProcess regulation of tRNA stability Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0036415 GO:0036416 biolink:BiologicalProcess tRNA stabilization Prevention of degradation of tRNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0036416 GO:0036406 biolink:CellularComponent anchored component of periplasmic side of cell outer membrane The component of the cell outer membrane consisting of gene products and protein complexes that are tethered to the periplasmic side of membrane by only a covalently attached anchor, embedded in the periplasmic side of the membrane only. go-plus.json anchored to periplasmic side of cell outer membrane|anchored to internal side of cell outer membrane http://purl.obolibrary.org/obo/GO_0036406 GO:1901039 biolink:BiologicalProcess regulation of peptide antigen transport Any process that modulates the frequency, rate or extent of peptide antigen transport. go-plus.json http://purl.obolibrary.org/obo/GO_1901039 GO:0061490 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061490 GO:0036407 biolink:CellularComponent mycolate outer membrane A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria). go-plus.json mycolate outer membrane|mycobacterial outer membrane|MOM|mycomembrane http://purl.obolibrary.org/obo/GO_0036407 GO:1901037 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle OBSOLETE. Any process that regulates transcription such that the target genes are transcribed during the M/G1 transition of the mitotic cell cycle. go-plus.json regulation of transcription from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter involved in M/G1 transition of mitotic cell cycle|regulation of gene-specific transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|global transcription regulation from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription during M/G1 transition of mitotic cell cycle|regulation of global transcription from Pol II promoter during M/G1 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_1901037 GO:0036408 biolink:MolecularActivity histone acetyltransferase activity (H3-K14 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14). go-plus.json histone lysine N-acetyltransferase activity (H3-K14 specific) http://purl.obolibrary.org/obo/GO_0036408 GO:0061491 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061491 GO:0061492 biolink:BiologicalProcess asymmetric protein localization to old or new spindle pole body Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically. go-plus.json http://purl.obolibrary.org/obo/GO_0061492 GO:0036409 biolink:CellularComponent histone H3-K14 acetyltransferase complex A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3. go-plus.json H3-K14 histone acetyltransferase complex|histone acetyltransferase complex (H3-K14 specific)|histone H3K14 acetyltransferase complex|histone H3 Lys 14 (H3K14) acetyltransferase complex http://purl.obolibrary.org/obo/GO_0036409 GO:1901038 biolink:BiologicalProcess cyanidin 3-O-glucoside metabolic process The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside. go-plus.json cyanidin 3-O-beta-D-glucoside metabolic process|cyanidin 3-O-beta-D-glucoside metabolism http://purl.obolibrary.org/obo/GO_1901038 GO:0061493 biolink:CellularComponent central plaque of mitotic spindle pole body One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0061493 GO:1901035 biolink:BiologicalProcess negative regulation of L-glutamine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell. go-plus.json negative regulation of L-glutamine import|down-regulation of L-glutamine uptake|negative regulation of L-glutamine uptake|downregulation of L-glutamine import|down-regulation of L-glutamine import|downregulation of L-glutamine uptake|down regulation of L-glutamine import|inhibition of L-glutamine import|down regulation of L-glutamine uptake|inhibition of L-glutamine uptake http://purl.obolibrary.org/obo/GO_1901035 GO:1901036 biolink:BiologicalProcess positive regulation of L-glutamine import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell. go-plus.json up-regulation of L-glutamine uptake|positive regulation of L-glutamine import|activation of L-glutamine uptake|up regulation of L-glutamine import|positive regulation of L-glutamine uptake|up regulation of L-glutamine uptake|upregulation of L-glutamine import|upregulation of L-glutamine uptake|up-regulation of L-glutamine import|activation of L-glutamine import http://purl.obolibrary.org/obo/GO_1901036 GO:0061494 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061494 GO:1901033 biolink:BiologicalProcess positive regulation of response to reactive oxygen species Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species. go-plus.json up-regulation of response to reactive oxygen species|up regulation of response to active oxygen species|upregulation of response to ROI|up regulation of response to ROS|activation of response to reactive oxygen intermediate|positive regulation of response to ROS|positive regulation of response to active oxygen species|positive regulation of response to reactive oxidative species|up regulation of response to reactive oxidative species|positive regulation of response to reactive oxygen intermediate|activation of response to active oxygen species|activation of response to ROS|upregulation of response to AOS|up regulation of response to reactive oxygen intermediate|upregulation of response to reactive oxygen species|up regulation of response to ROI|positive regulation of response to ROI|up-regulation of response to active oxygen species|up-regulation of response to ROS|upregulation of response to reactive oxidative species|activation of response to ROI|up regulation of response to AOS|upregulation of response to reactive oxygen intermediate|positive regulation of response to AOS|up regulation of response to reactive oxygen species|activation of response to reactive oxygen species|upregulation of response to active oxygen species|upregulation of response to ROS|up-regulation of response to reactive oxidative species|up-regulation of response to ROI|activation of response to AOS|up-regulation of response to reactive oxygen intermediate|activation of response to reactive oxidative species|up-regulation of response to AOS http://purl.obolibrary.org/obo/GO_1901033 GO:0061495 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061495 GO:0061496 biolink:CellularComponent half bridge of mitotic spindle pole body Structure adjacent to the plaques of the mitotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0061496 GO:1901034 biolink:BiologicalProcess regulation of L-glutamine import across plasma membrane Any process that modulates the frequency, rate or extent of L-glutamine import into cell. go-plus.json regulation of L-glutamine import|regulation of L-glutamine uptake http://purl.obolibrary.org/obo/GO_1901034 GO:0061497 biolink:CellularComponent inner plaque of mitotic spindle pole body One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0061497 GO:1901042 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901042 CHEBI:131582 biolink:ChemicalSubstance 8,12-diethyl-3-vinylbacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_131582 GO:1901043 biolink:BiologicalProcess obsolete protein polyubiquitination involved in cellular response to misfolded protein OBSOLETE. Any protein polyubiquitination that is involved in cellular response to misfolded protein. go-plus.json polyubiquitin of cellular response to misfolded protein|protein polyubiquitinylation of cellular response to misfolded protein|protein polyubiquitination involved in cellular response to misfolded protein|protein polyubiquitination of cellular response to misfolded protein|protein polyubiquitylation of cellular response to misfolded protein http://purl.obolibrary.org/obo/GO_1901043 GO:0061498 biolink:CellularComponent intermediate layer of mitotic spindle pole body Structure between the central and outer plaques of the mitotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0061498 GO:1901040 biolink:BiologicalProcess negative regulation of peptide antigen transport Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport. go-plus.json inhibition of peptide antigen transport|down regulation of peptide antigen transport|downregulation of peptide antigen transport|down-regulation of peptide antigen transport http://purl.obolibrary.org/obo/GO_1901040 GO:0061499 biolink:CellularComponent outer plaque of mitotic spindle pole body One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0061499 GO:0036400 biolink:MolecularActivity short neuropeptide F receptor activity Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide. go-plus.json sNPF receptor activity http://purl.obolibrary.org/obo/GO_0036400 GO:0036401 biolink:MolecularActivity pyrokinin receptor activity Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation. go-plus.json PK receptor activity http://purl.obolibrary.org/obo/GO_0036401 GO:1901041 biolink:BiologicalProcess positive regulation of peptide antigen transport Any process that activates or increases the frequency, rate or extent of peptide antigen transport. go-plus.json up-regulation of peptide antigen transport|upregulation of peptide antigen transport|up regulation of peptide antigen transport|activation of peptide antigen transport http://purl.obolibrary.org/obo/GO_1901041 GO:0036402 biolink:MolecularActivity proteasome-activating activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. EC:5.6.1.5 go-plus.json proteasomal ATPase activity|proteasome-activating ATPase activity|ATPase involved in positive regulation of proteasomal protein catabolic process|proteasome channel gating activity|proteasome channel opening activity http://purl.obolibrary.org/obo/GO_0036402 GO:0036403 biolink:MolecularActivity arachidonate 8(S)-lipoxygenase activity Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. KEGG_REACTION:R07053|RHEA:38675 go-plus.json 8-lipoxygenase (S-type)|8(S)-lipoxygenase activity http://purl.obolibrary.org/obo/GO_0036403 CHEBI:131587 biolink:ChemicalSubstance 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_131587 GO:0036404 biolink:BiologicalProcess conversion of ds siRNA to ss siRNA The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA). go-plus.json conversion of double-stranded small interfering RNA to single-stranded small interfering RNA http://purl.obolibrary.org/obo/GO_0036404 CHEBI:131588 biolink:ChemicalSubstance 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_131588 GO:0036405 biolink:CellularComponent anchored component of cell outer membrane The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json anchored to cell outer membrane http://purl.obolibrary.org/obo/GO_0036405 CHEBI:131589 biolink:ChemicalSubstance 3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid 9-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131589 CHEBI:26822 biolink:ChemicalSubstance sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_26822 CHEBI:26825 biolink:ChemicalSubstance sulfobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26825 CHEBI:75799 biolink:ChemicalSubstance 3-beta-D-glucosyl-1,2-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75799 chebi_ph7_3 CHEBI:26820 biolink:ChemicalSubstance sulfates go-plus.json http://purl.obolibrary.org/obo/CHEBI_26820 GO:0120219 biolink:CellularComponent subapical part of cell The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina. go-plus.json subapical region of cell http://purl.obolibrary.org/obo/GO_0120219 CHEBI:61151 biolink:ChemicalSubstance poly-ADP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61151 CHEBI:61150 biolink:ChemicalSubstance 2,3-dihydro-3-oxoanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61150 GO:0120215 biolink:BiologicalProcess positive regulation of histidine biosynthetic process Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process. go-plus.json up-regulation of histidine synthesis|up-regulation of histidine formation|up-regulation of histidine biosynthetic process|up-regulation of histidine biosynthesis|activation of histidine biosynthetic process|activation of histidine biosynthesis|upregulation of histidine anabolism|upregulation of histidine synthesis|upregulation of histidine formation|positive regulation of histidine biosynthesis|up regulation of histidine anabolism|activation of histidine anabolism|up regulation of histidine biosynthesis|up regulation of histidine biosynthetic process|positive regulation of histidine anabolism|up regulation of histidine synthesis|activation of histidine synthesis|positive regulation of histidine synthesis|up regulation of histidine formation|activation of histidine formation|positive regulation of histidine formation|upregulation of histidine biosynthetic process|upregulation of histidine biosynthesis|up-regulation of histidine anabolism http://purl.obolibrary.org/obo/GO_0120215 GO:0120216 biolink:CellularComponent matrilin complex A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer. go-plus.json matrilin-4 complex|matrilin family complex|matrilin-3 complex|matrilin-2 complex|matrilin-1 complex http://purl.obolibrary.org/obo/GO_0120216 GO:0120217 biolink:CellularComponent DNA gyrase complex A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB). go-plus.json topoisomerase II complex http://purl.obolibrary.org/obo/GO_0120217 GO:0120218 biolink:BiologicalProcess host interaction involved in quorum sensing A quorum sensing process that is modulated by some interaction with a host cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0120218 GO:2000063 biolink:BiologicalProcess positive regulation of ureter smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000063 GO:0120211 biolink:BiologicalProcess proacrosomal vesicle fusion Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0120211 CHEBI:61159 biolink:ChemicalSubstance conjugated linoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61159 GO:0120212 biolink:CellularComponent sperm head-tail coupling apparatus A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head. go-plus.json head-tail coupling apparatus|HTCA http://purl.obolibrary.org/obo/GO_0120212 GO:2000064 biolink:BiologicalProcess regulation of cortisol biosynthetic process Any process that modulates the frequency, rate or extent of cortisol biosynthetic process. go-plus.json regulation of cortisol biosynthesis|regulation of cortisol synthesis|regulation of cortisol anabolism|regulation of cortisol formation http://purl.obolibrary.org/obo/GO_2000064 GO:2000065 biolink:BiologicalProcess negative regulation of cortisol biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process. go-plus.json negative regulation of cortisol anabolism|negative regulation of cortisol synthesis|negative regulation of cortisol formation|negative regulation of cortisol biosynthesis http://purl.obolibrary.org/obo/GO_2000065 GO:0120213 biolink:BiologicalProcess regulation of histidine biosynthetic process Any process that modulates the frequency, rate or extent of histidine biosynthetic process. go-plus.json regulation of histidine anabolism|regulation of histidine synthesis|regulation of histidine formation|regulation of histidine biosynthesis http://purl.obolibrary.org/obo/GO_0120213 GO:2000066 biolink:BiologicalProcess positive regulation of cortisol biosynthetic process Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process. go-plus.json positive regulation of cortisol synthesis|positive regulation of cortisol anabolism|positive regulation of cortisol formation|positive regulation of cortisol biosynthesis http://purl.obolibrary.org/obo/GO_2000066 GO:0120214 biolink:BiologicalProcess negative regulation of histidine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process. go-plus.json inhibition of histidine formation|down regulation of histidine anabolism|down-regulation of histidine biosynthetic process|down-regulation of histidine biosynthesis|negative regulation of histidine biosynthesis|down regulation of histidine synthesis|downregulation of histidine anabolism|down regulation of histidine formation|downregulation of histidine synthesis|downregulation of histidine formation|downregulation of histidine biosynthetic process|downregulation of histidine biosynthesis|negative regulation of histidine anabolism|down-regulation of histidine anabolism|down regulation of histidine biosynthetic process|down regulation of histidine biosynthesis|negative regulation of histidine synthesis|down-regulation of histidine synthesis|inhibition of histidine biosynthetic process|inhibition of histidine biosynthesis|negative regulation of histidine formation|down-regulation of histidine formation|inhibition of histidine anabolism|inhibition of histidine synthesis http://purl.obolibrary.org/obo/GO_0120214 CHEBI:61158 biolink:ChemicalSubstance 3''-hydroxy-geranylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_61158 chebi_ph7_3 GO:2000067 biolink:BiologicalProcess regulation of root morphogenesis Any process that modulates the frequency, rate or extent of root morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000067 GO:2000068 biolink:BiologicalProcess regulation of defense response to insect Any process that modulates the frequency, rate or extent of defense response to insect. go-plus.json regulation of physiological defense response to insect http://purl.obolibrary.org/obo/GO_2000068 GO:2000069 biolink:BiologicalProcess regulation of post-embryonic root development Any process that modulates the frequency, rate or extent of post-embryonic root development. go-plus.json http://purl.obolibrary.org/obo/GO_2000069 GO:0120210 biolink:CellularComponent rod telodendria Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina. go-plus.json http://purl.obolibrary.org/obo/GO_0120210 CHEBI:75792 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75792 chebi_ph7_3 CHEBI:75793 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75793 chebi_ph7_3 CHEBI:26826 biolink:ChemicalSubstance dihydroxybenzenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26826 GO:2000060 biolink:BiologicalProcess positive regulation of ubiquitin-dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process. go-plus.json positive regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|positive regulation of protein degradation tagging activity|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitination during ubiquitin-dependent protein degradation|positive regulation of protein ubiquitination during ubiquitin-dependent protein breakdown http://purl.obolibrary.org/obo/GO_2000060 GO:2000061 biolink:BiologicalProcess regulation of ureter smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000061 GO:2000062 biolink:BiologicalProcess negative regulation of ureter smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000062 CHEBI:26829 biolink:ChemicalSubstance sulfoglycolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26829 CHEBI:26833 biolink:ChemicalSubstance sulfur atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_26833 chebi_ph7_3 CHEBI:26834 biolink:ChemicalSubstance sulfur-containing amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26834 CHEBI:26835 biolink:ChemicalSubstance sulfur molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_26835 CHEBI:26836 biolink:ChemicalSubstance sulfuric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26836 CHEBI:26830 biolink:ChemicalSubstance sulfonium compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_26830 CHEBI:26831 biolink:ChemicalSubstance N,N''-sulfonyldiurea go-plus.json http://purl.obolibrary.org/obo/CHEBI_26831 CHEBI:61162 biolink:ChemicalSubstance poly(3-hydroxycarboxylic acid) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_61162 CHEBI:61163 biolink:ChemicalSubstance D-alanyl-(R)-lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61163 CHEBI:61160 biolink:ChemicalSubstance conjugated linolenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61160 CHEBI:85110 biolink:ChemicalSubstance (3E,5Z)-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85110 chebi_ph7_3 GO:0120226 biolink:MolecularActivity succinyl-CoA binding Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component. go-plus.json succinyl-coenzyme A binding http://purl.obolibrary.org/obo/GO_0120226 CHEBI:85111 biolink:ChemicalSubstance 6-saturated-trans,trans-2,4-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85111 chebi_ph7_3 CHEBI:61166 biolink:ChemicalSubstance D-alanyl-(R)-lactic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61166 chebi_ph7_3 GO:0120227 biolink:MolecularActivity acyl-CoA binding Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid. go-plus.json acyl binding|acyl-coenzyme A binding http://purl.obolibrary.org/obo/GO_0120227 GO:0120228 biolink:CellularComponent outer dynein arm docking complex A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules. go-plus.json ODA docking complex|ODA-DC http://purl.obolibrary.org/obo/GO_0120228 GO:0120229 biolink:BiologicalProcess protein localization to motile cilium A process in which a protein is transported to, or maintained in, a location within a motile cilium. go-plus.json protein localization to nonmotile primary cilium http://purl.obolibrary.org/obo/GO_0120229 CHEBI:61165 biolink:ChemicalSubstance D-alanyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_61165 GO:0120222 biolink:BiologicalProcess regulation of blastocyst development Any process that modulates the frequency, rate or extent of blastocyst development. go-plus.json http://purl.obolibrary.org/obo/GO_0120222 GO:2000074 biolink:BiologicalProcess regulation of type B pancreatic cell development Any process that modulates the frequency, rate or extent of pancreatic B cell development. go-plus.json regulation of pancreatic beta cell development|regulation of pancreatic B cell development http://purl.obolibrary.org/obo/GO_2000074 GO:2000075 biolink:BiologicalProcess negative regulation of cytokinesis, site selection Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis. go-plus.json negative regulation of site selection involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_2000075 GO:0120223 biolink:BiologicalProcess larynx morphogenesis The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. go-plus.json laryngeal morphogenesis http://purl.obolibrary.org/obo/GO_0120223 GO:0120224 biolink:BiologicalProcess larynx development The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. go-plus.json http://purl.obolibrary.org/obo/GO_0120224 GO:2000076 biolink:BiologicalProcess positive regulation of cytokinesis, site selection Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis. go-plus.json positive regulation of site selection involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_2000076 GO:2000077 biolink:BiologicalProcess negative regulation of type B pancreatic cell development Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development. go-plus.json negative regulation of pancreatic beta cell development|negative regulation of pancreatic B cell development http://purl.obolibrary.org/obo/GO_2000077 GO:0120225 biolink:MolecularActivity coenzyme A binding Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. go-plus.json CoA binding http://purl.obolibrary.org/obo/GO_0120225 GO:2000078 biolink:BiologicalProcess positive regulation of type B pancreatic cell development Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. go-plus.json positive regulation of pancreatic B cell development|positive regulation of pancreatic beta cell development http://purl.obolibrary.org/obo/GO_2000078 GO:2000079 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. go-plus.json regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_2000079 GO:0120220 biolink:CellularComponent basal body patch The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster. go-plus.json centriolar patch http://purl.obolibrary.org/obo/GO_0120220 GO:0120221 biolink:BiologicalProcess maintenance of ciliary planar beating movement pattern Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement. go-plus.json http://purl.obolibrary.org/obo/GO_0120221 GO:2000070 biolink:BiologicalProcess regulation of response to water deprivation Any process that modulates the frequency, rate or extent of response to water deprivation. go-plus.json regulation of response to thirst|regulation of drought tolerance|regulation of response to drought|regulation of response to dehydration http://purl.obolibrary.org/obo/GO_2000070 GO:2000071 biolink:BiologicalProcess regulation of defense response by callose deposition Any process that modulates the frequency, rate or extent of defense response by callose deposition. go-plus.json regulation of callose deposition during defense response|regulation of callose localization during defense response http://purl.obolibrary.org/obo/GO_2000071 GO:2000072 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000072 GO:2000073 biolink:BiologicalProcess regulation of cytokinesis, site selection Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis. go-plus.json regulation of site selection involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_2000073 CHEBI:85140 biolink:ChemicalSubstance (9Z)-12-(phosphonooxy)octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85140 CHEBI:85141 biolink:ChemicalSubstance (9Z)-12-(phosphonooxy)octadecenoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85141 chebi_ph7_3 CHEBI:85142 biolink:ChemicalSubstance methyl nogalonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85142 GO:0120237 biolink:BiologicalProcess terminal acetylenic compound biosynthetic process The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom. go-plus.json terminal alkyne substituted compound anabolic process|terminal alkyne substituted compound anabolism|terminal alkyne substituted compound synthesis|terminal alkyne substituted compound biosynthesis|terminal alkyne substituted compound biosynthetic process http://purl.obolibrary.org/obo/GO_0120237 GO:0120238 biolink:CellularComponent sperm glycocalyx The carbohydrate rich layer at the outermost periphery of a sperm cell. go-plus.json http://purl.obolibrary.org/obo/GO_0120238 GO:0120239 biolink:CellularComponent vascular endothelial glycocalyx The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated. go-plus.json endothelial glycocalyx http://purl.obolibrary.org/obo/GO_0120239 GO:0120233 biolink:MolecularActivity prenyl-FMNH2 binding Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1. go-plus.json prenylated FMNH2 binding http://purl.obolibrary.org/obo/GO_0120233 CHEBI:85148 biolink:ChemicalSubstance 3-hydroxytetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85148 GO:2000085 biolink:BiologicalProcess negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. go-plus.json negative regulation of mesonephric mesenchyme to epithelial transition http://purl.obolibrary.org/obo/GO_2000085 GO:0120234 biolink:CellularComponent stereocilium coat A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle. go-plus.json stereocilium glycocalyx|auditory hair cell glycocalyx http://purl.obolibrary.org/obo/GO_0120234 GO:2000086 biolink:BiologicalProcess positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. go-plus.json positive regulation of mesonephric mesenchyme to epithelial transition http://purl.obolibrary.org/obo/GO_2000086 GO:2000087 biolink:BiologicalProcess regulation of mesonephric glomerulus development Any process that modulates the frequency, rate or extent of mesonephric glomerulus development. go-plus.json http://purl.obolibrary.org/obo/GO_2000087 GO:0120235 biolink:BiologicalProcess regulation of posttranslational protein targeting to membrane, translocation Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane. go-plus.json regulation of posttranslational endoplasmic reticulum membrane protein translocation|regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation|regulation of N-terminal signal peptide-independent translocation into the ER http://purl.obolibrary.org/obo/GO_0120235 GO:2000088 biolink:BiologicalProcess negative regulation of mesonephric glomerulus development Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development. go-plus.json http://purl.obolibrary.org/obo/GO_2000088 GO:0120236 biolink:BiologicalProcess negative regulation of posttranslational protein targeting to membrane, translocation Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane. go-plus.json negative regulation of N-terminal signal peptide-independent translocation into the ER|negative regulation of posttranslational endoplasmic reticulum membrane protein translocation|negative regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation http://purl.obolibrary.org/obo/GO_0120236 GO:2000089 biolink:BiologicalProcess positive regulation of mesonephric glomerulus development Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development. go-plus.json http://purl.obolibrary.org/obo/GO_2000089 GO:0120230 biolink:MolecularActivity recombinase activator activity Binds to and increases the activity of a recombinase. go-plus.json http://purl.obolibrary.org/obo/GO_0120230 GO:0120231 biolink:CellularComponent DNA recombinase auxiliary factor complex A protein complex that binds to a recombinase and incrseases its activity. go-plus.json DNA recombinase activator complex|DNA recombinase accessory factor complex http://purl.obolibrary.org/obo/GO_0120231 GO:0120232 biolink:BiologicalProcess prenyl-FMNH2 biosynthetic process The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1. go-plus.json prenyl-FMNH2 anabolism|prenylated FMNH2 anabolism|prenyl-FMNH2 synthesis|prenylated FMNH2 synthesis|prenyl-FMNH2 formation|prenylated FMNH2 formation|prenylated FMNH2 biosynthetic process|prenylated FMNH2 biosynthesis|prenyl-FMNH2 biosynthesis http://purl.obolibrary.org/obo/GO_0120232 GO:2000080 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. go-plus.json negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_2000080 GO:2000081 biolink:BiologicalProcess positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. go-plus.json positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_2000081 GO:2000082 biolink:BiologicalProcess regulation of L-ascorbic acid biosynthetic process Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process. go-plus.json regulation of ascorbate biosynthesis|regulation of ascorbate biosynthetic process|regulation of L-ascorbic acid anabolism|regulation of L-ascorbic acid synthesis|regulation of L-ascorbic acid formation|regulation of L-ascorbic acid biosynthesis|regulation of vitamin C biosynthetic process|regulation of vitamin C biosynthesis http://purl.obolibrary.org/obo/GO_2000082 CHEBI:26806 biolink:ChemicalSubstance succinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26806 GO:2000083 biolink:BiologicalProcess negative regulation of L-ascorbic acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process. go-plus.json negative regulation of L-ascorbic acid formation|negative regulation of ascorbate biosynthesis|negative regulation of ascorbate biosynthetic process|negative regulation of L-ascorbic acid biosynthesis|negative regulation of vitamin C biosynthesis|negative regulation of vitamin C biosynthetic process|negative regulation of L-ascorbic acid anabolism|negative regulation of L-ascorbic acid synthesis http://purl.obolibrary.org/obo/GO_2000083 GO:2000084 biolink:BiologicalProcess regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. go-plus.json regulation of mesonephric mesenchyme to epithelial transition http://purl.obolibrary.org/obo/GO_2000084 NCBITaxon:745062 biolink:OrganismalEntity Lactucinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_745062 PR:000013743 biolink:Protein Ras GTPase-activating protein 1 A protein that is a translation product of the human RASA1 gene or a 1:1 ortholog thereof. go-plus.json RASA|p120GAP|RASA1|RasGAP|GTPase-activating protein|ras p21 protein activator|GAP http://purl.obolibrary.org/obo/PR_000013743 CHEBI:85130 biolink:ChemicalSubstance 7,8-dihydroxanthopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85130 chebi_ph7_3 CHEBI:61185 biolink:ChemicalSubstance L-pipecolic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61185 chebi_ph7_3 GO:0120248 biolink:BiologicalProcess acetylenic compound catabolic process The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C). go-plus.json alkyne substituted compound degradation|alkyne substituted compound breakdown|alkyne substituted compound catabolic process|alkyne substituted compound catabolism http://purl.obolibrary.org/obo/GO_0120248 CHEBI:85133 biolink:ChemicalSubstance 12-(phosphonooxy)octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85133 CHEBI:85134 biolink:ChemicalSubstance 12-(phosphonooxy)octadecanoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85134 chebi_ph7_3 GO:0120249 biolink:CellularComponent lateral wall of outer hair cell The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae. go-plus.json outer hair cell lateral wall|lateral wall of OHC|OHC lateral wall http://purl.obolibrary.org/obo/GO_0120249 CHEBI:61186 biolink:ChemicalSubstance 7,8-dihydromonapterin 3-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61186 chebi_ph7_3 CHEBI:85136 biolink:ChemicalSubstance (9E)-12-(phosphonooxy)octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85136 GO:0120244 biolink:BiologicalProcess terminal acetylenic compound metabolic process The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom. go-plus.json terminal alkyne substituted compound metabolism|terminal alkyne substituted compound metabolic process http://purl.obolibrary.org/obo/GO_0120244 GO:2000096 biolink:BiologicalProcess positive regulation of Wnt signaling pathway, planar cell polarity pathway Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. go-plus.json positive regulation of non-canonical Wnt signaling pathway|positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway|positive regulation of Wnt-PCP signaling pathway|positive regulation of PCP pathway|positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway|positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway|positive regulation of Wnt-JNK signaling pathway http://purl.obolibrary.org/obo/GO_2000096 CHEBI:85137 biolink:ChemicalSubstance (9E)-12-(phosphonooxy)octadecenoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85137 chebi_ph7_3 GO:2000097 biolink:BiologicalProcess regulation of smooth muscle cell-matrix adhesion Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_2000097 GO:0120245 biolink:BiologicalProcess terminal acetylenic compound catabolic process The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom. go-plus.json terminal alkyne substituted compound degradation|terminal alkyne substituted compound breakdown|terminal alkyne substituted compound catabolic process|terminal alkyne substituted compound catabolism http://purl.obolibrary.org/obo/GO_0120245 GO:0120246 biolink:BiologicalProcess acetylenic compound metabolic process The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C). go-plus.json alkyne substituted compound metabolism|alkyne substituted compound metabolic process http://purl.obolibrary.org/obo/GO_0120246 GO:2000098 biolink:BiologicalProcess negative regulation of smooth muscle cell-matrix adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_2000098 CHEBI:85139 biolink:ChemicalSubstance beta-amino acid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_85139 GO:0120247 biolink:BiologicalProcess acetylenic compound biosynthetic process The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C). go-plus.json alkyne substituted compound biosynthetic process|alkyne substituted compound biosynthesis|alkyne substituted compound anabolism|alkyne substituted compound synthesis|alkyne substituted compound anabolic process http://purl.obolibrary.org/obo/GO_0120247 GO:2000099 biolink:BiologicalProcess regulation of establishment or maintenance of bipolar cell polarity Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity. go-plus.json http://purl.obolibrary.org/obo/GO_2000099 GO:0120240 biolink:CellularComponent platelet glycocalyx The carbohydrate rich layer at the outermost periphery of a platelet. go-plus.json http://purl.obolibrary.org/obo/GO_0120240 GO:0120241 biolink:MolecularActivity 2-iminobutanoate/2-iminopropanoate deaminase Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. EC:3.5.99.10 go-plus.json enamine/imine deaminase|2-iminobutanoate deaminase|2-iminopropanoate deaminase|imine intermediate deaminase activity http://purl.obolibrary.org/obo/GO_0120241 GO:0120242 biolink:MolecularActivity 2-iminobutanoate deaminase activity Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+). KEGG_REACTION:R11098|RHEA:39975|MetaCyc:RXN-15123 go-plus.json 2-iminobutanoate/2-iminopropanoate deaminase http://purl.obolibrary.org/obo/GO_0120242 GO:0120243 biolink:MolecularActivity 2-iminopropanoate deaminase activity Catalysis of the reaction: 2-iminopropanoate + H2O = NH4(+) + pyruvate. RHEA:40671|KEGG_REACTION:R11099|MetaCyc:RXN-15127 go-plus.json 2-iminobutanoate/2-iminopropanoate deaminase http://purl.obolibrary.org/obo/GO_0120243 CHEBI:26819 biolink:ChemicalSubstance sulfuric ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_26819 chebi_ph7_3 GO:2000090 biolink:BiologicalProcess regulation of mesonephric glomerular mesangial cell proliferation Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000090 GO:2000091 biolink:BiologicalProcess negative regulation of mesonephric glomerular mesangial cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000091 GO:2000092 biolink:BiologicalProcess positive regulation of mesonephric glomerular mesangial cell proliferation Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000092 GO:2000093 biolink:BiologicalProcess regulation of mesonephric nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000093 CHEBI:26816 biolink:ChemicalSubstance carbohydrate phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26816 GO:2000094 biolink:BiologicalProcess negative regulation of mesonephric nephron tubule epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000094 GO:2000095 biolink:BiologicalProcess regulation of Wnt signaling pathway, planar cell polarity pathway Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. go-plus.json regulation of PCP pathway|regulation of Wnt-activated signaling pathway, planar cell polarity pathway|regulation of Wnt-JNK signaling pathway|regulation of non-canonical Wnt signaling pathway|regulation of Wnt receptor signalling pathway, planar cell polarity pathway|regulation of Wnt receptor signaling pathway, planar cell polarity pathway|regulation of Wnt-PCP signaling pathway http://purl.obolibrary.org/obo/GO_2000095 CHEBI:61191 biolink:ChemicalSubstance 7,8-dihydromonapterin 3-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61191 CHEBI:61190 biolink:ChemicalSubstance beta-D-GalpNAc-(1->4)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_61190 chebi_ph7_3 GO:2000027 biolink:BiologicalProcess regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of animal organ morphogenesis. go-plus.json regulation of histogenesis and organogenesis http://purl.obolibrary.org/obo/GO_2000027 GO:2000028 biolink:BiologicalProcess regulation of photoperiodism, flowering Any process that modulates the frequency, rate or extent of photoperiodism, flowering. go-plus.json regulation of response to day length, flowering|regulation of photoperiodic control of inflorescence development|regulation of response to night length, flowering|regulation of photoperiodic control of flowering time|regulation of response to photoperiod, flowering http://purl.obolibrary.org/obo/GO_2000028 GO:2000029 biolink:BiologicalProcess regulation of proanthocyanidin biosynthetic process Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process. go-plus.json regulation of proanthocyanidin biosynthesis|regulation of proanthocyanidin anabolism|regulation of proanthocyanidin synthesis|regulation of proanthocyanidin formation http://purl.obolibrary.org/obo/GO_2000029 CHEBI:61194 biolink:ChemicalSubstance 2'-deoxyinosine 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61194 chebi_ph7_3 CHEBI:85165 biolink:ChemicalSubstance prostaglandin G2 2-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_85165 chebi_ph7_3 CHEBI:85166 biolink:ChemicalSubstance prostaglandin H2 2-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_85166 chebi_ph7_3 CHEBI:61197 biolink:ChemicalSubstance phlobaphene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61197 GO:2000020 biolink:BiologicalProcess positive regulation of male gonad development Any process that activates or increases the frequency, rate or extent of male gonad development. go-plus.json positive regulation of testis development|positive regulation of testicular development http://purl.obolibrary.org/obo/GO_2000020 GO:0061400 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to calcium ion Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061400 GO:2000021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000021 GO:0061401 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0061401 GO:2000022 biolink:BiologicalProcess regulation of jasmonic acid mediated signaling pathway Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway. go-plus.json regulation of jasmonic acid mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000022 GO:0061402 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to acidic pH Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7. go-plus.json positive regulation of transcription from RNA polymerase II promoter in response to acidity http://purl.obolibrary.org/obo/GO_0061402 GO:2000023 biolink:BiologicalProcess regulation of lateral root development Any process that modulates the frequency, rate or extent of lateral root development. go-plus.json http://purl.obolibrary.org/obo/GO_2000023 GO:0061403 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. go-plus.json http://purl.obolibrary.org/obo/GO_0061403 GO:2000024 biolink:BiologicalProcess regulation of leaf development Any process that modulates the frequency, rate or extent of leaf development. go-plus.json http://purl.obolibrary.org/obo/GO_2000024 GO:2000025 biolink:BiologicalProcess regulation of leaf formation Any process that modulates the frequency, rate or extent of leaf formation. go-plus.json http://purl.obolibrary.org/obo/GO_2000025 GO:0061404 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to increased salt OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0061404 GO:0061405 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. go-plus.json http://purl.obolibrary.org/obo/GO_0061405 GO:2000026 biolink:BiologicalProcess regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of multicellular organismal development. go-plus.json http://purl.obolibrary.org/obo/GO_2000026 GO:0061406 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0061406 GO:0061407 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061407 GO:0061408 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to heat stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. go-plus.json http://purl.obolibrary.org/obo/GO_0061408 GO:0061409 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to freezing Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius. go-plus.json http://purl.obolibrary.org/obo/GO_0061409 CHEBI:85150 biolink:ChemicalSubstance (9Z)-12-hydroxyoctadec-9-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85150 chebi_ph7_3 GO:2000038 biolink:BiologicalProcess regulation of stomatal complex development Any process that modulates the frequency, rate or extent of stomatal complex development. go-plus.json http://purl.obolibrary.org/obo/GO_2000038 GO:2000039 biolink:BiologicalProcess regulation of trichome morphogenesis Any process that modulates the frequency, rate or extent of trichome morphogenesis. go-plus.json regulation of trichome cell morphogenesis during differentiation http://purl.obolibrary.org/obo/GO_2000039 CHEBI:85152 biolink:ChemicalSubstance (9E)-12-hydroxyoctadec-9-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85152 chebi_ph7_3 GO:2000030 biolink:BiologicalProcess regulation of response to red or far red light Any process that modulates the frequency, rate or extent of response to red or far red light. go-plus.json http://purl.obolibrary.org/obo/GO_2000030 GO:2000031 biolink:BiologicalProcess regulation of salicylic acid mediated signaling pathway Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway. go-plus.json regulation of salicylic acid mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000031 GO:2000032 biolink:BiologicalProcess regulation of secondary shoot formation Any process that modulates the frequency, rate or extent of secondary shoot formation. go-plus.json regulation of auxiliary shoot formation|regulation of axillary shoot system formation|regulation of axillary shoot formation|regulation of shoot branching http://purl.obolibrary.org/obo/GO_2000032 GO:2000033 biolink:BiologicalProcess regulation of seed dormancy process Any process that modulates the frequency, rate or extent of seed dormancy process. go-plus.json regulation of seed dormancy http://purl.obolibrary.org/obo/GO_2000033 GO:2000034 biolink:BiologicalProcess regulation of seed maturation Any process that modulates the frequency, rate or extent of seed maturation. go-plus.json http://purl.obolibrary.org/obo/GO_2000034 GO:2000035 biolink:BiologicalProcess regulation of stem cell division Any process that modulates the frequency, rate or extent of stem cell division. go-plus.json regulation of stem cell renewal http://purl.obolibrary.org/obo/GO_2000035 GO:2000036 biolink:BiologicalProcess regulation of stem cell population maintenance Any process that modulates the frequency, rate or extent of stem cell population maintenance. go-plus.json regulation of maintenance of pluripotency http://purl.obolibrary.org/obo/GO_2000036 GO:2000037 biolink:BiologicalProcess regulation of stomatal complex patterning Any process that modulates the frequency, rate or extent of stomatal complex patterning. go-plus.json http://purl.obolibrary.org/obo/GO_2000037 GO:2000049 biolink:BiologicalProcess positive regulation of cell-cell adhesion mediated by cadherin Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin. go-plus.json http://purl.obolibrary.org/obo/GO_2000049 CHEBI:85184 biolink:ChemicalSubstance dihydroxycholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85184 CHEBI:85187 biolink:ChemicalSubstance L-iduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85187 CHEBI:85189 biolink:ChemicalSubstance O-[(9Z)-hexadecenoyl]-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85189 chebi_ph7_3 GO:0061420 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to biotin starvation Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin. go-plus.json http://purl.obolibrary.org/obo/GO_0061420 GO:2000041 biolink:BiologicalProcess negative regulation of planar cell polarity pathway involved in axis elongation Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation. go-plus.json http://purl.obolibrary.org/obo/GO_2000041 GO:0036497 biolink:BiologicalProcess eIF2alpha dephosphorylation in response to endoplasmic reticulum stress The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress. go-plus.json eIF2alpha dephosphorylation in response to ER stress|regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_0036497 GO:0036498 biolink:BiologicalProcess IRE1-mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB. go-plus.json IRE1alpha unfolded protein response|UPR signaling by IRE1 stress sensor|inositol-requiring transmembrane kinase/endonuclease signal transduction|IRE1 signaling in response to endoplasmic reticulum stress|IRE1 signal transduction pathway|inositol-requiring enzyme 1-mediated unfolded protein response|IRE1p unfolded protein response|endoplasmic reticulum unfolded protein response; IRE1 signaling|ERN1-mediated unfolded protein response|IRE1 branch of UPR http://purl.obolibrary.org/obo/GO_0036498 GO:0061421 biolink:BiologicalProcess positive regulation of transcription by oleic acid Any process involving oleic acid that activates or increases the rate of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0061421 GO:2000042 biolink:BiologicalProcess negative regulation of double-strand break repair via homologous recombination Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination. go-plus.json negative regulation of HRR|negative regulation of Rad51-dependent recombinational repair|negative regulation of Rhp51-dependent recombinational repair|negative regulation of HDR|negative regulation of homologous recombinational repair|negative regulation of homology-directed repair http://purl.obolibrary.org/obo/GO_2000042 GO:2000043 biolink:BiologicalProcess regulation of cardiac cell fate specification Any process that modulates the frequency, rate or extent of cardiac cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_2000043 GO:0061422 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0. go-plus.json positive regulation of transcription from RNA polymerase II promoter in response to alkalinity http://purl.obolibrary.org/obo/GO_0061422 GO:0036499 biolink:BiologicalProcess PERK-mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity. go-plus.json UPR signaling by PERK stress sensor|PERK signaling in response to endoplasmic reticulum stress|PERK signal transduction pathway|endoplasmic reticulum unfolded protein response; PERK signaling|EIF2AK3-mediated unfolded protein response|PKR-like ER kinase signal transduction|PERK branch of UPR|eukaryotic translation initiation factor 2-alpha kinase 3-mediated unfolded protein response http://purl.obolibrary.org/obo/GO_0036499 GO:2000044 biolink:BiologicalProcess negative regulation of cardiac cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_2000044 GO:0061423 biolink:BiologicalProcess positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0061423 GO:2000045 biolink:BiologicalProcess regulation of G1/S transition of mitotic cell cycle Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_2000045 GO:0061424 biolink:BiologicalProcess obsolete positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization. go-plus.json positive regulation of peroxisome organisation by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0061424 GO:2000046 biolink:BiologicalProcess obsolete regulation of G2 phase of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of G2 phase of mitotic cell cycle. go-plus.json regulation of G2 phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2000046 GO:0061425 biolink:BiologicalProcess positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0061425 GO:2000047 biolink:BiologicalProcess regulation of cell-cell adhesion mediated by cadherin Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin. go-plus.json http://purl.obolibrary.org/obo/GO_2000047 GO:0061426 biolink:BiologicalProcess positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport. go-plus.json http://purl.obolibrary.org/obo/GO_0061426 GO:0061427 biolink:BiologicalProcess obsolete negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0061427 GO:2000048 biolink:BiologicalProcess negative regulation of cell-cell adhesion mediated by cadherin Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin. go-plus.json http://purl.obolibrary.org/obo/GO_2000048 GO:0061428 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to hypoxia Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061428 GO:0036490 biolink:BiologicalProcess regulation of translation in response to endoplasmic reticulum stress Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. go-plus.json regulation of translation in response to ER stress http://purl.obolibrary.org/obo/GO_0036490 GO:0061429 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter by oleic acid Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0061429 GO:0036491 biolink:BiologicalProcess regulation of translation initiation in response to endoplasmic reticulum stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress. go-plus.json regulation of translation initiation in response to ER stress http://purl.obolibrary.org/obo/GO_0036491 GO:0036492 biolink:BiologicalProcess eiF2alpha phosphorylation in response to endoplasmic reticulum stress The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress. go-plus.json eiF2alpha phosphorylation in response to ER stress|regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_0036492 GO:0036493 biolink:BiologicalProcess positive regulation of translation in response to endoplasmic reticulum stress Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. go-plus.json positive regulation of translation in response to ER stress http://purl.obolibrary.org/obo/GO_0036493 GO:0036494 biolink:BiologicalProcess positive regulation of translation initiation in response to endoplasmic reticulum stress Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress. go-plus.json positive regulation of translation initiation in response to ER stress http://purl.obolibrary.org/obo/GO_0036494 GO:0036495 biolink:BiologicalProcess negative regulation of translation initiation in response to endoplasmic reticulum stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress. go-plus.json negative regulation of translation initiation in response to ER stress http://purl.obolibrary.org/obo/GO_0036495 GO:2000040 biolink:BiologicalProcess regulation of planar cell polarity pathway involved in axis elongation Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation. go-plus.json http://purl.obolibrary.org/obo/GO_2000040 GO:0036496 biolink:BiologicalProcess regulation of translational initiation by eIF2 alpha dephosphorylation Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha. go-plus.json http://purl.obolibrary.org/obo/GO_0036496 CHEBI:85171 biolink:ChemicalSubstance sphingoid-1-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85171 chebi_ph7_3 GO:0120208 biolink:CellularComponent telodendria Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0120208 CHEBI:85173 biolink:ChemicalSubstance 11-epi-prostaglandin F2alpha(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85173 chebi_ph7_3 CHEBI:85174 biolink:ChemicalSubstance prostaglandin D2 ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_85174 chebi_ph7_3 GO:0120209 biolink:CellularComponent cone telodendria Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina. go-plus.json http://purl.obolibrary.org/obo/GO_0120209 CHEBI:85175 biolink:ChemicalSubstance 11beta-prostaglandin F2alpha ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_85175 chebi_ph7_3 GO:0120204 biolink:MolecularActivity methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2. go-plus.json http://purl.obolibrary.org/obo/GO_0120204 GO:0120205 biolink:CellularComponent photoreceptor proximal connecting cilium The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR. go-plus.json photoreceptor PCC|PCC http://purl.obolibrary.org/obo/GO_0120205 GO:0120206 biolink:CellularComponent photoreceptor distal connecting cilium The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability. go-plus.json DCC|photoreceptor DCC http://purl.obolibrary.org/obo/GO_0120206 GO:0120207 biolink:BiologicalProcess endocytosis, site selection The process of selecting and or marking the position where endocytosis will occur. go-plus.json http://purl.obolibrary.org/obo/GO_0120207 GO:0036486 biolink:BiologicalProcess ventral trunk neural crest cell migration The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta. go-plus.json ventral trunk NCC migration|trunk NCC migration within somite|trunk NCC migration through anterior sclerotome http://purl.obolibrary.org/obo/GO_0036486 GO:2000052 biolink:BiologicalProcess positive regulation of non-canonical Wnt signaling pathway Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway. go-plus.json positive regulation of non-canonical Wnt receptor signalling pathway|positive regulation of beta-catenin-independent Wnt receptor signaling pathway|positive regulation of non-canonical Wnt-activated signaling pathway|positive regulation of non-canonical Wnt receptor signaling pathway http://purl.obolibrary.org/obo/GO_2000052 GO:0120200 biolink:CellularComponent rod photoreceptor outer segment The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0120200 GO:0036487 biolink:MolecularActivity nitric-oxide synthase inhibitor activity Binds to and stops, prevents or reduces the activity of nitric oxide synthase. go-plus.json nitric oxide synthase inhibitor activity|NOS inhibitor activity http://purl.obolibrary.org/obo/GO_0036487 GO:0120201 biolink:CellularComponent cone photoreceptor disc membrane Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0120201 GO:2000053 biolink:BiologicalProcess regulation of Wnt signaling pathway involved in dorsal/ventral axis specification Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. go-plus.json regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification http://purl.obolibrary.org/obo/GO_2000053 GO:0061410 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to ethanol Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061410 GO:0036488 biolink:CellularComponent CHOP-C/EBP complex A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors. go-plus.json CHOP-C/EBP heterodimer|GADD153-C/EBP complex|GADD153-C/EBP-alpha complex|CHOP-C/EBP dimer http://purl.obolibrary.org/obo/GO_0036488 GO:0061411 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to cold Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. go-plus.json http://purl.obolibrary.org/obo/GO_0061411 GO:0120202 biolink:CellularComponent rod photoreceptor disc membrane Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment. go-plus.json http://purl.obolibrary.org/obo/GO_0120202 GO:2000054 biolink:BiologicalProcess negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. go-plus.json negative regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification http://purl.obolibrary.org/obo/GO_2000054 GO:0120203 biolink:CellularComponent rod photoreceptor disc lumen The volume enclosed by the membrane of a rod photoreceptor cell disc membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0120203 GO:0036489 biolink:BiologicalProcess neuromelanin biosynthetic process The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers. go-plus.json neuromelanin anabolism|neuromelanin biosynthesis|neuromelanin synthesis|neuromelanin formation http://purl.obolibrary.org/obo/GO_0036489 GO:2000055 biolink:BiologicalProcess positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. go-plus.json positive regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification http://purl.obolibrary.org/obo/GO_2000055 GO:0061412 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids. go-plus.json http://purl.obolibrary.org/obo/GO_0061412 GO:2000056 biolink:BiologicalProcess regulation of Wnt signaling pathway involved in digestive tract morphogenesis Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis. go-plus.json regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis http://purl.obolibrary.org/obo/GO_2000056 GO:0061413 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. go-plus.json http://purl.obolibrary.org/obo/GO_0061413 GO:0061414 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. go-plus.json http://purl.obolibrary.org/obo/GO_0061414 GO:2000057 biolink:BiologicalProcess negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis. go-plus.json negative regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|negative regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis http://purl.obolibrary.org/obo/GO_2000057 GO:0061415 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. go-plus.json http://purl.obolibrary.org/obo/GO_0061415 GO:2000058 biolink:BiologicalProcess regulation of ubiquitin-dependent protein catabolic process Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process. go-plus.json regulation of protein degradation tagging activity|regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation|regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitination during ubiquitin-dependent protein degradation|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_2000058 GO:2000059 biolink:BiologicalProcess negative regulation of ubiquitin-dependent protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process. go-plus.json negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|negative regulation of protein degradation tagging activity|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_2000059 GO:0061416 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to salt stress OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0061416 GO:0061417 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0061417 GO:0061418 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to hypoxia Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061418 GO:0036480 biolink:BiologicalProcess neuron intrinsic apoptotic signaling pathway in response to oxidative stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. go-plus.json neuron apoptosis in response to oxidative stress|oxidative stress-induced neuronal apoptosis|oxidative stress-induced neuron apoptosis http://purl.obolibrary.org/obo/GO_0036480 GO:0061419 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to hypoxia Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061419 GO:0036481 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to hydrogen peroxide A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2). go-plus.json intrinsic apoptotic signaling pathway in response to H2O2|H2O2-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced apoptosis http://purl.obolibrary.org/obo/GO_0036481 GO:0036482 biolink:BiologicalProcess neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide. go-plus.json hydrogen peroxide-induced neuronal apoptosis|neuron apoptosis in response to hydrogen peroxide|hydrogen peroxide-induced neuron apoptosis|H2O2-induced neuron intrinsic apoptotic signaling pathway|neuron intrinsic apoptotic signaling pathway in response to H2O2 http://purl.obolibrary.org/obo/GO_0036482 GO:0036483 biolink:BiologicalProcess neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. go-plus.json endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|ER stress-induced neuron intrinsic apoptotic signaling pathway|endoplasmic reticulum stress-induced neuron apoptosis|ER stress-induced neuron apoptosis http://purl.obolibrary.org/obo/GO_0036483 GO:2000050 biolink:BiologicalProcess regulation of non-canonical Wnt signaling pathway Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway. go-plus.json regulation of beta-catenin-independent Wnt receptor signaling pathway|regulation of non-canonical Wnt-activated signaling pathway|regulation of non-canonical Wnt receptor signalling pathway|regulation of non-canonical Wnt receptor signaling pathway http://purl.obolibrary.org/obo/GO_2000050 GO:0036484 biolink:BiologicalProcess trunk neural crest cell migration The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. go-plus.json trunk NCC migration http://purl.obolibrary.org/obo/GO_0036484 GO:0036485 biolink:BiologicalProcess dorsolateral trunk neural crest cell migration The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells. go-plus.json dorsolateral trunk NCC migration http://purl.obolibrary.org/obo/GO_0036485 GO:2000051 biolink:BiologicalProcess negative regulation of non-canonical Wnt signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway. go-plus.json negative regulation of non-canonical Wnt receptor signalling pathway|negative regulation of beta-catenin-independent Wnt receptor signaling pathway|negative regulation of non-canonical Wnt-activated signaling pathway|negative regulation of non-canonical Wnt receptor signaling pathway http://purl.obolibrary.org/obo/GO_2000051 CHEBI:26789 biolink:ChemicalSubstance streptothricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26789 CHEBI:75712 biolink:ChemicalSubstance (S)-mecoprop go-plus.json http://purl.obolibrary.org/obo/CHEBI_75712 CHEBI:75717 biolink:ChemicalSubstance (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75717 chebi_ph7_3 CHEBI:26787 biolink:ChemicalSubstance streptomycin phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26787 CHEBI:75714 biolink:ChemicalSubstance dUMP residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_75714 CHEBI:26788 biolink:ChemicalSubstance streptomycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26788 CHEBI:36104 biolink:ChemicalSubstance 1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36104 CHEBI:36105 biolink:ChemicalSubstance (2R)-flavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36105 chebi_ph7_3 CHEBI:36102 biolink:ChemicalSubstance (2R)-flavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_36102 chebi_ph7_3 CHEBI:36103 biolink:ChemicalSubstance (2S)-flavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_36103 chebi_ph7_3 UBERON:0013525 biolink:AnatomicalEntity stomach lumen The anatomical space that is enclosed by a stomach. go-plus.json cavity of stomach|gastric cavity http://purl.obolibrary.org/obo/UBERON_0013525 CHEBI:36108 biolink:ChemicalSubstance 1-hydroxy-2-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36108 UBERON:0013526 biolink:AnatomicalEntity otocyst lumen A anatomical cavity that is part of a ear vesicle. go-plus.json lumen of otocyst http://purl.obolibrary.org/obo/UBERON_0013526 CHEBI:36109 biolink:ChemicalSubstance piperidinecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36109 CHEBI:36106 biolink:ChemicalSubstance 2-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36106 CHEBI:36107 biolink:ChemicalSubstance 2-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36107 chebi_ph7_3 CHEBI:36100 biolink:ChemicalSubstance (S)-isoflavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_36100 chebi_ph7_3 CHEBI:36101 biolink:ChemicalSubstance (R)-isoflavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_36101 chebi_ph7_3 CHEBI:51737 biolink:ChemicalSubstance alpha,beta-unsaturated carboxylic ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51737 CHEBI:75728 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75728 chebi_ph7_3 CHEBI:51732 biolink:ChemicalSubstance cycloheptatriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51732 CHEBI:26799 biolink:ChemicalSubstance styrenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_26799 UBERON:0013522 biolink:AnatomicalEntity subdivision of tube go-plus.json http://purl.obolibrary.org/obo/UBERON_0013522 CHEBI:75729 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75729 chebi_ph7_3 CHEBI:36115 biolink:ChemicalSubstance 1H-isochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36115 chebi_ph7_3 CHEBI:36116 biolink:ChemicalSubstance 3H-isochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36116 chebi_ph7_3 CHEBI:36114 biolink:ChemicalSubstance chromenylium go-plus.json http://purl.obolibrary.org/obo/CHEBI_36114 chebi_ph7_3 UBERON:0013514 biolink:AnatomicalEntity space surrounding organism The space that surrounds an organism. go-plus.json external to organism|outside of body http://purl.obolibrary.org/obo/UBERON_0013514 UBERON:0013515 biolink:AnatomicalEntity subdivision of oviduct A section through the tube or network of tubes that connects the ovaries to the outside of the body. go-plus.json subdivision of uterine tube|subdivision of fallopian tube|zone of uterine tube|uterine tube zone|subdivision of oviduct http://purl.obolibrary.org/obo/UBERON_0013515 CHEBI:36117 biolink:ChemicalSubstance isochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36117 CHEBI:36112 biolink:ChemicalSubstance pyridinedicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36112 CHEBI:36110 biolink:ChemicalSubstance pipecolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36110 CHEBI:75735 biolink:ChemicalSubstance 1,3-dioleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75735 chebi_ph7_3 CHEBI:26763 biolink:ChemicalSubstance steroid glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26763 CHEBI:26764 biolink:ChemicalSubstance steroid hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26764 CHEBI:51720 biolink:ChemicalSubstance ynal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51720 chebi_ph7_3 CHEBI:51721 biolink:ChemicalSubstance alpha,beta-unsaturated ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51721 CHEBI:26766 biolink:ChemicalSubstance steroid lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26766 CHEBI:26761 biolink:ChemicalSubstance steroid antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_26761 UBERON:0013507 biolink:AnatomicalEntity thoracic vertebra cartilage element A thoracic vertebra endochondral element that is composed primarily of cartilage tissue. go-plus.json thoracic vertebral cartilage condensation group http://purl.obolibrary.org/obo/UBERON_0013507 UBERON:0013508 biolink:AnatomicalEntity thoracic vertebra pre-cartilage condensation A thoracic vertebra endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013508 UBERON:0013503 biolink:AnatomicalEntity caudal vertebra cartilage element A caudal vertebra endochondral element that is composed primarily of cartilage tissue. go-plus.json tail vertebral cartilage condensation|coccygeal vertebral cartilage condensation group|coccygeal vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_0013503 UBERON:0013504 biolink:AnatomicalEntity caudal vertebra pre-cartilage condensation A caudal vertebra endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json coccygeal vertebra pre-cartilage condensation|tail vertebral pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0013504 UBERON:0013505 biolink:AnatomicalEntity cervical vertebra cartilage element A cervical vertebra endochondral element that is composed primarily of cartilage tissue. go-plus.json cervical vertebral cartilage condensation group http://purl.obolibrary.org/obo/UBERON_0013505 CHEBI:566825 biolink:ChemicalSubstance propan-1-aminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_566825 chebi_ph7_3 UBERON:0013506 biolink:AnatomicalEntity cervical vertebra pre-cartilage condensation A cervical vertebra endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013506 CHEBI:12154 biolink:ChemicalSubstance 5-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12154 chebi_ph7_3 CHEBI:75730 biolink:ChemicalSubstance carminomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75730 chebi_ph7_3 CHEBI:26775 biolink:ChemicalSubstance stilbene go-plus.json http://purl.obolibrary.org/obo/CHEBI_26775 chebi_ph7_3 CHEBI:26776 biolink:ChemicalSubstance stilbenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26776 UBERON:0013501 biolink:AnatomicalEntity cloacal sphincter A sphincter muscle that is part of a cloaca. go-plus.json sphincter cloacae http://purl.obolibrary.org/obo/UBERON_0013501 UBERON:0013502 biolink:AnatomicalEntity 5th arch mesenchyme A mesenchyme that is part of a pharyngeal arch 5. go-plus.json 5th pharyngeal arch mesenchyme|5th branchial arch mesenchyme|pharyngeal arch 5 mesenchyme http://purl.obolibrary.org/obo/UBERON_0013502 CHEBI:26773 biolink:ChemicalSubstance stigmastane go-plus.json http://purl.obolibrary.org/obo/CHEBI_26773 chebi_ph7_3 CHEBI:51718 biolink:ChemicalSubstance alpha,beta-unsaturated aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_51718 CHEBI:61109 biolink:ChemicalSubstance pyrimidine nucleotide-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_61109 CHEBI:26745 biolink:ChemicalSubstance spirostan go-plus.json http://purl.obolibrary.org/obo/CHEBI_26745 chebi_ph7_3 CHEBI:75757 biolink:ChemicalSubstance 1-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75757 chebi_ph7_3 CHEBI:51702 biolink:ChemicalSubstance enoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51702 chebi_ph7_3 CHEBI:51703 biolink:ChemicalSubstance glyoxylate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_51703 chebi_ph7_3 CHEBI:26747 biolink:ChemicalSubstance squalene triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26747 CHEBI:51704 biolink:ChemicalSubstance glyoxylates go-plus.json http://purl.obolibrary.org/obo/CHEBI_51704 chebi_ph7_3 CHEBI:26743 biolink:ChemicalSubstance sphing-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26743 CHEBI:75759 biolink:ChemicalSubstance beta-L-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_75759 CHEBI:51705 biolink:ChemicalSubstance octacarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51705 CHEBI:61111 biolink:ChemicalSubstance aminophosphonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61111 CHEBI:61112 biolink:ChemicalSubstance methyl thiocyanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61112 chebi_ph7_3 CHEBI:61115 biolink:ChemicalSubstance EC 3.5.1.98 (histone deacetylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_61115 CHEBI:61114 biolink:ChemicalSubstance N-(4-aminobenzoyl)-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61114 CHEBI:61119 biolink:ChemicalSubstance dTDP-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61119 CHEBI:75767 biolink:ChemicalSubstance animal metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_75767 CHEBI:75768 biolink:ChemicalSubstance mammalian metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_75768 CHEBI:26759 biolink:ChemicalSubstance sterigmatocystins go-plus.json http://purl.obolibrary.org/obo/CHEBI_26759 CHEBI:75769 biolink:ChemicalSubstance B vitamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_75769 CHEBI:61122 biolink:ChemicalSubstance 3-geranyl-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61122 CHEBI:61123 biolink:ChemicalSubstance (E)-4-(trimethylammonio)but-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61123 CHEBI:61120 biolink:ChemicalSubstance nucleobase-containing molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_61120 CHEBI:61121 biolink:ChemicalSubstance oxylipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61121 CHEBI:61126 biolink:ChemicalSubstance 5,6,7,8-tetrahydropterin-6-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61126 CHEBI:61125 biolink:ChemicalSubstance 7-carboxy-7-deazaguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61125 CHEBI:61129 biolink:ChemicalSubstance N-hydroxy-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61129 CHEBI:75763 biolink:ChemicalSubstance eukaryotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_75763 CHEBI:26725 biolink:ChemicalSubstance glucitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26725 CHEBI:61130 biolink:ChemicalSubstance hydroxy-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61130 CHEBI:61133 biolink:ChemicalSubstance N,N-dihydroxy-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61133 chebi_ph7_3 CHEBI:85100 biolink:ChemicalSubstance 4,5-saturated-trans-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85100 chebi_ph7_3 CHEBI:61134 biolink:ChemicalSubstance 2-methylbutanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_61134 chebi_ph7_3 CHEBI:85101 biolink:ChemicalSubstance trans,trans-2,4-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85101 chebi_ph7_3 CHEBI:61131 biolink:ChemicalSubstance N-hydroxy-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61131 chebi_ph7_3 CHEBI:61132 biolink:ChemicalSubstance N,N-dihydroxy-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61132 CHEBI:61138 biolink:ChemicalSubstance N-hydroxy-L-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61138 CHEBI:61135 biolink:ChemicalSubstance (E)-2-methylbutanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_61135 chebi_ph7_3 CHEBI:61136 biolink:ChemicalSubstance (Z)-2-methylbutanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_61136 chebi_ph7_3 CHEBI:85108 biolink:ChemicalSubstance trans-3-cis-5-octadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85108 chebi_ph7_3 CHEBI:61139 biolink:ChemicalSubstance hydroxy-L-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61139 CHEBI:12113 biolink:ChemicalSubstance 5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_12113 chebi_ph7_3 CHEBI:75771 biolink:ChemicalSubstance mouse metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_75771 CHEBI:75772 biolink:ChemicalSubstance Saccharomyces cerevisiae metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_75772 CHEBI:26735 biolink:ChemicalSubstance substituted spermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26735 CHEBI:75787 biolink:ChemicalSubstance prokaryotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_75787 CHEBI:61140 biolink:ChemicalSubstance N-hydroxy-L-valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61140 chebi_ph7_3 CHEBI:61141 biolink:ChemicalSubstance N,N-dihydroxy-L-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61141 CHEBI:61144 biolink:ChemicalSubstance (Z)-2-methylpropanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_61144 chebi_ph7_3 CHEBI:12109 biolink:ChemicalSubstance 5-aminolevulinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12109 CHEBI:61142 biolink:ChemicalSubstance N,N-dihydroxy-L-valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61142 chebi_ph7_3 CHEBI:61143 biolink:ChemicalSubstance (E)-2-methylpropanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_61143 chebi_ph7_3 CHEBI:61148 biolink:ChemicalSubstance drimenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61148 chebi_ph7_3 CHEBI:61149 biolink:ChemicalSubstance 2,3-dihydro-3-oxoanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61149 CHEBI:61146 biolink:ChemicalSubstance 4-nitrophenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61146 chebi_ph7_3 CHEBI:61147 biolink:ChemicalSubstance ferroheme d1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61147 CHEBI:26738 biolink:ChemicalSubstance sphingenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26738 CHEBI:26739 biolink:ChemicalSubstance sphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26739 CHEBI:36191 biolink:ChemicalSubstance hexenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36191 CHEBI:36192 biolink:ChemicalSubstance 2-hexenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36192 CHEBI:145844 biolink:ChemicalSubstance PE(14:1_22:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145844 CHEBI:36190 biolink:ChemicalSubstance hepoxilin A3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_36190 CHEBI:145847 biolink:ChemicalSubstance PE(20:2_20:3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145847 CHEBI:36188 biolink:ChemicalSubstance malate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_36188 CHEBI:36186 biolink:ChemicalSubstance cyclobutanedicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36186 CHEBI:145832 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 26:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145832 CHEBI:145833 biolink:ChemicalSubstance phosphatidylglycerol 27:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145833 CHEBI:36194 biolink:ChemicalSubstance cyclohexadienedicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36194 CHEBI:36197 biolink:ChemicalSubstance pyrandicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36197 CHEBI:36166 biolink:ChemicalSubstance 5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36166 CHEBI:36167 biolink:ChemicalSubstance dipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36167 chebi_ph7_3 CHEBI:36164 biolink:ChemicalSubstance amino dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36164 CHEBI:36165 biolink:ChemicalSubstance pimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36165 chebi_ph7_3 CHEBI:36180 biolink:ChemicalSubstance butenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36180 chebi_ph7_3 CHEBI:36181 biolink:ChemicalSubstance succinate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_36181 CHEBI:145813 biolink:ChemicalSubstance D-cystine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_145813 chebi_ph7_3 CHEBI:36173 biolink:ChemicalSubstance pyridinedicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36173 CHEBI:36174 biolink:ChemicalSubstance octenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36174 CHEBI:145814 biolink:ChemicalSubstance EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_145814 CHEBI:51793 biolink:ChemicalSubstance (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51793 CHEBI:36178 biolink:ChemicalSubstance cytoporphyrins go-plus.json http://purl.obolibrary.org/obo/CHEBI_36178 CHEBI:36175 biolink:ChemicalSubstance octenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36175 CHEBI:36148 biolink:ChemicalSubstance 4-hydroxy-2-oxoglutarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36148 CHEBI:36149 biolink:ChemicalSubstance 2-hydroxyglutarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36149 CHEBI:36147 biolink:ChemicalSubstance oxo dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36147 CHEBI:36140 biolink:ChemicalSubstance cyclopentanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_36140 CHEBI:36141 biolink:ChemicalSubstance quinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36141 CHEBI:145806 biolink:ChemicalSubstance (R)-(+)-perillyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_145806 chebi_ph7_3 CHEBI:36144 biolink:ChemicalSubstance ferriheme b go-plus.json http://purl.obolibrary.org/obo/CHEBI_36144 CHEBI:36145 biolink:ChemicalSubstance oxo dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36145 OBA:0006038 biolink:OntologyClass concentration of of calcium ion in cytosol The concentration of of a calcium ion when measured in cytosol. go-plus.json cytosol calcium ion concentration of http://purl.obolibrary.org/obo/OBA_0006038 CHEBI:36159 biolink:ChemicalSubstance protoporphyrinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36159 CHEBI:36157 biolink:ChemicalSubstance muconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36157 chebi_ph7_3 CHEBI:36158 biolink:ChemicalSubstance metalloprotoporphyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_36158 CHEBI:12164 biolink:ChemicalSubstance 5-phosphoribosyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12164 CHEBI:36126 biolink:ChemicalSubstance cyclohexenecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36126 CHEBI:36124 biolink:ChemicalSubstance (+)-quinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36124 CHEBI:36125 biolink:ChemicalSubstance cyclitol carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36125 CHEBI:36128 biolink:ChemicalSubstance cyclopropanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36128 chebi_ph7_3 CHEBI:36129 biolink:ChemicalSubstance pentenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36129 CHEBI:12195 biolink:ChemicalSubstance 6-O-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_12195 CHEBI:36123 biolink:ChemicalSubstance cyclitol carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36123 CHEBI:36121 biolink:ChemicalSubstance flavylium go-plus.json http://purl.obolibrary.org/obo/CHEBI_36121 chebi_ph7_3 CHEBI:12194 biolink:ChemicalSubstance 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_12194 CHEBI:75700 biolink:ChemicalSubstance (13R)-hydroxy-(14S,15S)-epoxyicosa-(5Z,8Z,11Z)-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75700 CHEBI:75705 biolink:ChemicalSubstance D-glucosaminic acid 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75705 chebi_ph7_3 CHEBI:75703 biolink:ChemicalSubstance (R)-mecoprop go-plus.json http://purl.obolibrary.org/obo/CHEBI_75703 CHEBI:75704 biolink:ChemicalSubstance 2-(4-chloro-2-methylphenoxy)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75704 CHEBI:36130 biolink:ChemicalSubstance cyclic terpene ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36130 CHEBI:51750 biolink:ChemicalSubstance alpha,beta-unsaturated carboxylic acid amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_51750 CHEBI:51751 biolink:ChemicalSubstance enamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_51751 chebi_ph7_3 CHEBI:36133 biolink:ChemicalSubstance pentenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36133 CHEBI:36134 biolink:ChemicalSubstance glutaconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36134 chebi_ph7_3 CHEBI:36132 biolink:ChemicalSubstance alicyclic ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36132 GO:1901329 biolink:BiologicalProcess regulation of odontoblast differentiation Any process that modulates the frequency, rate or extent of odontoblast differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1901329 GO:1901327 biolink:BiologicalProcess response to tacrolimus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus. go-plus.json response to tacrolimus hydrate|response to FK506 http://purl.obolibrary.org/obo/GO_1901327 GO:1901328 biolink:BiologicalProcess response to cytochalasin B Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901328 GO:1901325 biolink:BiologicalProcess response to antimycin A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901325 GO:1901326 biolink:BiologicalProcess response to tetracycline Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901326 GO:1901323 biolink:BiologicalProcess response to erythromycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901323 GO:1901324 biolink:BiologicalProcess response to trichodermin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901324 GO:1901321 biolink:BiologicalProcess positive regulation of heart induction Any process that activates or increases the frequency, rate or extent of heart induction. go-plus.json up-regulation of heart induction|upregulation of heart induction|up regulation of heart induction|activation of heart induction http://purl.obolibrary.org/obo/GO_1901321 GO:0061560 biolink:BiologicalProcess cranial ganglion formation The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json cranial ganglia formation http://purl.obolibrary.org/obo/GO_0061560 GO:1901322 biolink:BiologicalProcess response to chloramphenicol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901322 GO:0061561 biolink:BiologicalProcess trigeminal ganglion formation The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json trigeminal ganglia formation http://purl.obolibrary.org/obo/GO_0061561 GO:0061562 biolink:BiologicalProcess cranial ganglion structural organization The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure. go-plus.json cranial ganglia structural organization http://purl.obolibrary.org/obo/GO_0061562 GO:1901320 biolink:BiologicalProcess negative regulation of heart induction Any process that stops, prevents or reduces the frequency, rate or extent of heart induction. go-plus.json inhibition of heart induction|down regulation of heart induction|downregulation of heart induction|down-regulation of heart induction http://purl.obolibrary.org/obo/GO_1901320 GO:0061563 biolink:BiologicalProcess trigeminal ganglion structural organization The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure. go-plus.json trigeminal ganglia organization http://purl.obolibrary.org/obo/GO_0061563 GO:0061564 biolink:BiologicalProcess axon development The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). go-plus.json http://purl.obolibrary.org/obo/GO_0061564 GO:0061565 biolink:BiologicalProcess dAMP phosphorylation The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP. go-plus.json http://purl.obolibrary.org/obo/GO_0061565 GO:0061566 biolink:BiologicalProcess CMP phosphorylation The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061566 GO:0061567 biolink:BiologicalProcess dCMP phosphorylation The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061567 GO:0061568 biolink:BiologicalProcess GDP phosphorylation The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061568 GO:0061569 biolink:BiologicalProcess UDP phosphorylation The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061569 GO:1901338 biolink:MolecularActivity catecholamine binding Binding to catecholamine. go-plus.json http://purl.obolibrary.org/obo/GO_1901338 CHEBI:85072 biolink:ChemicalSubstance 15-dehydroprostaglandin A1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85072 chebi_ph7_3 CHEBI:85073 biolink:ChemicalSubstance 12-methyloctadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85073 GO:1901339 biolink:BiologicalProcess regulation of store-operated calcium channel activity Any process that modulates the frequency, rate or extent of store-operated calcium channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_1901339 GO:1901336 biolink:BiologicalProcess lactone biosynthetic process The chemical reactions and pathways resulting in the formation of lactone. go-plus.json lactone anabolism|lactone synthesis|lactone formation|lactone biosynthesis http://purl.obolibrary.org/obo/GO_1901336 CHEBI:85074 biolink:ChemicalSubstance 2-methylhexadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85074 GO:1901337 biolink:BiologicalProcess thioester transport The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901337 CHEBI:85075 biolink:ChemicalSubstance 3-methylundecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85075 GO:1901334 biolink:BiologicalProcess lactone metabolic process The chemical reactions and pathways involving lactone. go-plus.json lactone metabolism http://purl.obolibrary.org/obo/GO_1901334 CHEBI:85076 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85076 GO:1901335 biolink:BiologicalProcess lactone catabolic process The chemical reactions and pathways resulting in the breakdown of lactone. go-plus.json lactone catabolism|lactone degradation|lactone breakdown http://purl.obolibrary.org/obo/GO_1901335 CHEBI:85077 biolink:ChemicalSubstance isomyristoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85077 GO:1901332 biolink:BiologicalProcess negative regulation of lateral root development Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development. go-plus.json inhibition of lateral root development|down-regulation of lateral root development|downregulation of lateral root development|down regulation of lateral root development http://purl.obolibrary.org/obo/GO_1901332 GO:1901333 biolink:BiologicalProcess positive regulation of lateral root development Any process that activates or increases the frequency, rate or extent of lateral root development. go-plus.json upregulation of lateral root development|activation of lateral root development|up-regulation of lateral root development|up regulation of lateral root development http://purl.obolibrary.org/obo/GO_1901333 GO:1901330 biolink:BiologicalProcess negative regulation of odontoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation. go-plus.json down-regulation of odontoblast differentiation|inhibition of odontoblast differentiation|down regulation of odontoblast differentiation|downregulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_1901330 GO:0061550 biolink:BiologicalProcess cranial ganglion development The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. go-plus.json cranial ganglia development http://purl.obolibrary.org/obo/GO_0061550 GO:1901331 biolink:BiologicalProcess positive regulation of odontoblast differentiation Any process that activates or increases the frequency, rate or extent of odontoblast differentiation. go-plus.json up regulation of odontoblast differentiation|activation of odontoblast differentiation|up-regulation of odontoblast differentiation|upregulation of odontoblast differentiation http://purl.obolibrary.org/obo/GO_1901331 GO:0061551 biolink:BiologicalProcess trigeminal ganglion development The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. go-plus.json trigeminal ganglia development http://purl.obolibrary.org/obo/GO_0061551 GO:0061552 biolink:BiologicalProcess ganglion morphogenesis The process in which the anatomical structures of ganglion are generated and organized. go-plus.json ganglia morphogenesis http://purl.obolibrary.org/obo/GO_0061552 GO:1901340 biolink:BiologicalProcess negative regulation of store-operated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity. go-plus.json down regulation of store-operated calcium channel activity|downregulation of store-operated calcium channel activity|down-regulation of store-operated calcium channel activity|inhibition of store-operated calcium channel activity http://purl.obolibrary.org/obo/GO_1901340 GO:0061553 biolink:BiologicalProcess ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. go-plus.json ganglia maturation http://purl.obolibrary.org/obo/GO_0061553 GO:0061554 biolink:BiologicalProcess ganglion formation The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json ganglia formation http://purl.obolibrary.org/obo/GO_0061554 GO:0061555 biolink:BiologicalProcess ganglion structural organization The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure. go-plus.json ganglia structural organization http://purl.obolibrary.org/obo/GO_0061555 GO:0061556 biolink:BiologicalProcess trigeminal ganglion morphogenesis The process in which the anatomical structure of a trigeminal ganglion is generated and organized. go-plus.json trigeminal ganglia morphogenesis http://purl.obolibrary.org/obo/GO_0061556 GO:0061557 biolink:BiologicalProcess trigeminal ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. go-plus.json trigeminal ganglia maturation http://purl.obolibrary.org/obo/GO_0061557 GO:0061558 biolink:BiologicalProcess cranial ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. go-plus.json cranial ganglia maturation http://purl.obolibrary.org/obo/GO_0061558 GO:0061559 biolink:BiologicalProcess cranial ganglion morphogenesis The process in which the anatomical structure of a cranial ganglion is generated and organized. go-plus.json cranial ganglia morphogenesis http://purl.obolibrary.org/obo/GO_0061559 GO:1901349 biolink:BiologicalProcess glucosinolate transport The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901349 GO:1901347 biolink:BiologicalProcess negative regulation of secondary cell wall biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis. go-plus.json negative regulation of secondary cell wall synthesis|down-regulation of secondary cell wall synthesis|down regulation of cellulose and pectin-containing secondary cell wall biogenesis|negative regulation of secondary cell wall formation|down-regulation of secondary cell wall formation|negative regulation of secondary cell wall biosynthetic process|down-regulation of secondary cell wall biosynthetic process|down-regulation of secondary cell wall biogenesis|inhibition of cellulose and pectin-containing secondary cell wall biogenesis|inhibition of secondary cell wall anabolism|inhibition of plant-type secondary cell wall biogenesis|inhibition of secondary cell wall synthesis|downregulation of secondary cell wall biosynthetic process|downregulation of secondary cell wall biogenesis|down regulation of secondary cell wall anabolism|inhibition of secondary cell wall formation|down regulation of plant-type secondary cell wall biogenesis|down regulation of secondary cell wall biosynthetic process|down regulation of secondary cell wall biogenesis|inhibition of secondary cell wall biogenesis|downregulation of secondary cell wall anabolism|down regulation of secondary cell wall synthesis|negative regulation of cellulose and pectin-containing secondary cell wall biogenesis|downregulation of plant-type secondary cell wall biogenesis|down-regulation of cellulose and pectin-containing secondary cell wall biogenesis|down regulation of secondary cell wall formation|downregulation of secondary cell wall synthesis|inhibition of secondary cell wall biosynthetic process|downregulation of secondary cell wall formation|negative regulation of secondary cell wall anabolism|down-regulation of secondary cell wall anabolism|down-regulation of plant-type secondary cell wall biogenesis|negative regulation of plant-type secondary cell wall biogenesis|downregulation of cellulose and pectin-containing secondary cell wall biogenesis http://purl.obolibrary.org/obo/GO_1901347 GO:1901348 biolink:BiologicalProcess positive regulation of secondary cell wall biogenesis Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis. go-plus.json activation of secondary cell wall synthesis|up-regulation of secondary cell wall anabolism|activation of secondary cell wall biosynthetic process|upregulation of cellulose and pectin-containing secondary cell wall biogenesis|up-regulation of plant-type secondary cell wall biogenesis|activation of secondary cell wall formation|up-regulation of secondary cell wall synthesis|positive regulation of secondary cell wall biosynthetic process|up regulation of secondary cell wall biosynthetic process|up-regulation of secondary cell wall formation|up regulation of secondary cell wall biogenesis|upregulation of secondary cell wall anabolism|upregulation of plant-type secondary cell wall biogenesis|up-regulation of cellulose and pectin-containing secondary cell wall biogenesis|upregulation of secondary cell wall synthesis|upregulation of secondary cell wall formation|activation of cellulose and pectin-containing secondary cell wall biogenesis|upregulation of secondary cell wall biosynthetic process|upregulation of secondary cell wall biogenesis|up regulation of secondary cell wall anabolism|up regulation of plant-type secondary cell wall biogenesis|positive regulation of cellulose and pectin-containing secondary cell wall biogenesis|positive regulation of secondary cell wall anabolism|positive regulation of plant-type secondary cell wall biogenesis|up regulation of secondary cell wall synthesis|up regulation of cellulose and pectin-containing secondary cell wall biogenesis|positive regulation of secondary cell wall synthesis|up-regulation of secondary cell wall biosynthetic process|up regulation of secondary cell wall formation|activation of secondary cell wall anabolism|up-regulation of secondary cell wall biogenesis|activation of plant-type secondary cell wall biogenesis|activation of secondary cell wall biogenesis|positive regulation of secondary cell wall formation http://purl.obolibrary.org/obo/GO_1901348 GO:1901345 biolink:BiologicalProcess response to L-thialysine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus. go-plus.json response to thialysine http://purl.obolibrary.org/obo/GO_1901345 GO:1901346 biolink:BiologicalProcess negative regulation of vasculature development involved in avascular cornea development in camera-type eye Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye. go-plus.json downregulation of vascular system development involved in avascular cornea development|downregulation of vasculature development involved in avascular cornea development in camera-type eye|down regulation of vascular system development involved in avascular cornea development|negative regulation of vascular system development involved in avascular cornea development in camera-type eye|down-regulation of vascular system development involved in avascular cornea development in camera-type eye|down-regulation of vasculature development involved in avascular cornea development|negative regulation of vasculature development involved in avascular cornea development|inhibition of vascular system development involved in avascular cornea development|down-regulation of vasculature development involved in avascular cornea development in camera-type eye|inhibition of vasculature development involved in avascular cornea development in camera-type eye|downregulation of vasculature development involved in avascular cornea development|inhibition of vascular system development involved in avascular cornea development in camera-type eye|down regulation of vasculature development involved in avascular cornea development|negative regulation of vascular system development involved in avascular cornea development|down-regulation of vascular system development involved in avascular cornea development|inhibition of vasculature development involved in avascular cornea development|down regulation of vascular system development involved in avascular cornea development in camera-type eye|downregulation of vascular system development involved in avascular cornea development in camera-type eye|down regulation of vasculature development involved in avascular cornea development in camera-type eye http://purl.obolibrary.org/obo/GO_1901346 GO:0061580 biolink:BiologicalProcess colon epithelial cell migration The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0061580 GO:1901343 biolink:BiologicalProcess negative regulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. go-plus.json negative regulation of vascular system development|down-regulation of vascular system development|down-regulation of vasculature development|inhibition of vasculature development|inhibition of vascular system development|down regulation of vascular system development|downregulation of vascular system development|down regulation of vasculature development|downregulation of vasculature development http://purl.obolibrary.org/obo/GO_1901343 GO:0061581 biolink:BiologicalProcess corneal epithelial cell migration The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0061581 GO:0061582 biolink:BiologicalProcess intestinal epithelial cell migration The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0061582 GO:1901344 biolink:BiologicalProcess response to leptomycin B Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901344 GO:0061583 biolink:BiologicalProcess colon epithelial cell chemotaxis The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_0061583 GO:1901341 biolink:BiologicalProcess positive regulation of store-operated calcium channel activity Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity. go-plus.json up regulation of store-operated calcium channel activity|activation of store-operated calcium channel activity|up-regulation of store-operated calcium channel activity|upregulation of store-operated calcium channel activity http://purl.obolibrary.org/obo/GO_1901341 GO:1901342 biolink:BiologicalProcess regulation of vasculature development Any process that modulates the frequency, rate or extent of vasculature development. go-plus.json regulation of vascular system development http://purl.obolibrary.org/obo/GO_1901342 GO:0061584 biolink:BiologicalProcess hypocretin secretion The controlled release of hypocretin from a cell or a tissue. go-plus.json orexin secretion http://purl.obolibrary.org/obo/GO_0061584 GO:1901350 biolink:BiologicalProcess obsolete cell-cell signaling involved in cell-cell junction organization OBSOLETE. Any cell-cell signaling that is involved in cell-cell junction organization. go-plus.json cell-cell signalling involved in intercellular junction assembly and maintenance|cell-cell signaling involved in cell-cell junction assembly and maintenance|cell-cell signaling involved in intercellular junction assembly and maintenance|cell-cell signalling involved in cell-cell junction biogenesis|cell-cell signalling involved in cell-cell junction organisation|cell-cell signalling involved in cell-cell junction organization|cell-cell signaling involved in cell-cell junction biogenesis|cell-cell signaling involved in cell-cell junction organisation|cell-cell signalling involved in cell-cell junction assembly and maintenance http://purl.obolibrary.org/obo/GO_1901350 GO:0061585 biolink:BiologicalProcess hypocretin secretion, neurotransmission The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter. go-plus.json orexin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061585 GO:1901351 biolink:BiologicalProcess regulation of phosphatidylglycerol biosynthetic process Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process. go-plus.json regulation of phosphatidylglycerol formation|regulation of phosphatidylglycerol biosynthesis|regulation of phosphatidylglycerol anabolism|regulation of phosphatidylglycerol synthesis http://purl.obolibrary.org/obo/GO_1901351 GO:0061586 biolink:BiologicalProcess positive regulation of transcription by transcription factor localization Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor. go-plus.json http://purl.obolibrary.org/obo/GO_0061586 GO:0061587 biolink:BiologicalProcess transfer RNA gene-mediated silencing The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes. go-plus.json tRNA gene-mediated chromatin silencing|transfer RNA gene-mediated chromatin silencing|transfer RNA gene-mediated gene silencing|tgm silencing|tRNA gene-mediated gene silencing http://purl.obolibrary.org/obo/GO_0061587 GO:0061588 biolink:BiologicalProcess calcium activated phospholipid scrambling The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061588 GO:0061589 biolink:BiologicalProcess calcium activated phosphatidylserine scrambling The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061589 CHEBI:9107 biolink:ChemicalSubstance senecionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9107 CHEBI:9100 biolink:ChemicalSubstance Sem-tRNA(Met) go-plus.json http://purl.obolibrary.org/obo/CHEBI_9100 CHEBI:85090 biolink:ChemicalSubstance (3E,5Z,8Z,11Z,14Z)-icosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85090 chebi_ph7_3 CHEBI:85091 biolink:ChemicalSubstance (2E,4E,8Z,11Z,14Z)-icosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85091 chebi_ph7_3 GO:1901358 biolink:BiologicalProcess beta-D-galactofuranose biosynthetic process The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose. go-plus.json beta-D-galactofuranose anabolism|beta-D-galactofuranose biosynthesis|beta-D-galactofuranose synthesis|beta-D-galactofuranose formation http://purl.obolibrary.org/obo/GO_1901358 CHEBI:85097 biolink:ChemicalSubstance 4-saturated trans-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85097 chebi_ph7_3 GO:1901359 biolink:MolecularActivity tungstate binding Binding to tungstate. go-plus.json http://purl.obolibrary.org/obo/GO_1901359 GO:1901356 biolink:BiologicalProcess beta-D-galactofuranose metabolic process The chemical reactions and pathways involving beta-D-galactofuranose. go-plus.json beta-D-galactofuranose metabolism http://purl.obolibrary.org/obo/GO_1901356 GO:1901357 biolink:BiologicalProcess beta-D-galactofuranose catabolic process The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose. go-plus.json beta-D-galactofuranose catabolism|beta-D-galactofuranose degradation|beta-D-galactofuranose breakdown http://purl.obolibrary.org/obo/GO_1901357 CHEBI:85099 biolink:ChemicalSubstance (2E,4Z)-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85099 chebi_ph7_3 GO:0061570 biolink:BiologicalProcess dCDP phosphorylation The process of introducing a phosphate group into dCDP to produce a dCTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061570 GO:1901354 biolink:BiologicalProcess response to L-canavanine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901354 GO:0061571 biolink:BiologicalProcess TDP phosphorylation The process of introducing a phosphate group into TDP to produce a TTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061571 GO:1901355 biolink:BiologicalProcess response to rapamycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901355 GO:1901352 biolink:BiologicalProcess negative regulation of phosphatidylglycerol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process. go-plus.json inhibition of phosphatidylglycerol synthesis|down regulation of phosphatidylglycerol formation|inhibition of phosphatidylglycerol formation|down regulation of phosphatidylglycerol biosynthesis|down regulation of phosphatidylglycerol biosynthetic process|downregulation of phosphatidylglycerol biosynthetic process|downregulation of phosphatidylglycerol biosynthesis|down-regulation of phosphatidylglycerol anabolism|negative regulation of phosphatidylglycerol anabolism|down-regulation of phosphatidylglycerol biosynthesis|down-regulation of phosphatidylglycerol biosynthetic process|negative regulation of phosphatidylglycerol synthesis|down-regulation of phosphatidylglycerol synthesis|negative regulation of phosphatidylglycerol biosynthesis|down-regulation of phosphatidylglycerol formation|negative regulation of phosphatidylglycerol formation|downregulation of phosphatidylglycerol anabolism|inhibition of phosphatidylglycerol biosynthetic process|inhibition of phosphatidylglycerol biosynthesis|down regulation of phosphatidylglycerol anabolism|downregulation of phosphatidylglycerol synthesis|inhibition of phosphatidylglycerol anabolism|downregulation of phosphatidylglycerol formation|down regulation of phosphatidylglycerol synthesis http://purl.obolibrary.org/obo/GO_1901352 GO:0061572 biolink:BiologicalProcess actin filament bundle organization A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. go-plus.json actin filament cable organization http://purl.obolibrary.org/obo/GO_0061572 GO:1901353 biolink:BiologicalProcess positive regulation of phosphatidylglycerol biosynthetic process Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process. go-plus.json upregulation of phosphatidylglycerol biosynthetic process|upregulation of phosphatidylglycerol biosynthesis|upregulation of phosphatidylglycerol synthesis|upregulation of phosphatidylglycerol formation|up-regulation of phosphatidylglycerol anabolism|activation of phosphatidylglycerol anabolism|up-regulation of phosphatidylglycerol synthesis|activation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol biosynthetic process|up regulation of phosphatidylglycerol biosynthesis|activation of phosphatidylglycerol biosynthetic process|activation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol biosynthesis|activation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol anabolism|up regulation of phosphatidylglycerol anabolism|positive regulation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol synthesis|up-regulation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol biosynthetic process|positive regulation of phosphatidylglycerol formation|up regulation of phosphatidylglycerol formation|upregulation of phosphatidylglycerol anabolism http://purl.obolibrary.org/obo/GO_1901353 GO:0061573 biolink:BiologicalProcess actin filament bundle retrograde transport A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell. go-plus.json actin filament cable retrograde transport http://purl.obolibrary.org/obo/GO_0061573 GO:1901361 biolink:BiologicalProcess organic cyclic compound catabolic process The chemical reactions and pathways resulting in the breakdown of organic cyclic compound. go-plus.json organic cyclic compound breakdown|organic cyclic compound catabolism|organic cyclic compound degradation http://purl.obolibrary.org/obo/GO_1901361 GO:0061574 biolink:CellularComponent ASAP complex A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1. go-plus.json http://purl.obolibrary.org/obo/GO_0061574 GO:0061575 biolink:MolecularActivity cyclin-dependent protein serine/threonine kinase activator activity Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase. go-plus.json cyclin-dependent protein kinase 5 activator activity http://purl.obolibrary.org/obo/GO_0061575 GO:1901362 biolink:BiologicalProcess organic cyclic compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic cyclic compound. go-plus.json organic cyclic compound anabolism|organic cyclic compound synthesis|organic cyclic compound biosynthesis|organic cyclic compound formation http://purl.obolibrary.org/obo/GO_1901362 GO:0061576 biolink:CellularComponent acyl-CoA ceramide synthase complex A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1. go-plus.json http://purl.obolibrary.org/obo/GO_0061576 GO:1901360 biolink:BiologicalProcess organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound. go-plus.json organic cyclic compound metabolism http://purl.obolibrary.org/obo/GO_1901360 GO:0061577 biolink:BiologicalProcess calcium ion transmembrane transport via high voltage-gated calcium channel A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel. go-plus.json generation of L-type calcium current http://purl.obolibrary.org/obo/GO_0061577 GO:0061578 biolink:MolecularActivity Lys63-specific deubiquitinase activity Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein. Reactome:R-HSA-936381|Reactome:R-HSA-5691411|Reactome:R-HSA-5690856|Reactome:R-HSA-5357845|Reactome:R-HSA-741411|Reactome:R-HSA-5691431|Reactome:R-HSA-688136|Reactome:R-HSA-936390|Reactome:R-HSA-5691439|Reactome:R-HSA-5696547|Reactome:R-HSA-8869506 go-plus.json http://purl.obolibrary.org/obo/GO_0061578 GO:0061579 biolink:MolecularActivity N-acyl homoserine lactone synthase activity Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone. EC:2.3.1.184|RHEA:10096 go-plus.json autoinducer-1 synthase http://purl.obolibrary.org/obo/GO_0061579 NCBITaxon:1648017 biolink:OrganismalEntity Hordeinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648017 GO:1901369 biolink:BiologicalProcess cyclic 2,3-bisphospho-D-glycerate biosynthetic process The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid. go-plus.json cDPG biosynthesis|cyclic 2,3-diphosphoglycerate biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid biosynthetic process|cyclic 2,3-bisphospho-D-glyceric acid anabolism|cyclic 2,3-bisphospho-D-glyceric acid biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid synthesis|cyclic 2,3-bisphospho-D-glyceric acid formation http://purl.obolibrary.org/obo/GO_1901369 GO:1901367 biolink:BiologicalProcess response to L-cysteine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901367 GO:1901368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901368 GO:1901365 biolink:BiologicalProcess funalenone catabolic process The chemical reactions and pathways resulting in the breakdown of funalenone. go-plus.json funalenone catabolism|funalenone degradation|funalenone breakdown http://purl.obolibrary.org/obo/GO_1901365 GO:1901366 biolink:BiologicalProcess funalenone biosynthetic process The chemical reactions and pathways resulting in the formation of funalenone. go-plus.json funalenone biosynthesis|funalenone anabolism|funalenone synthesis|funalenone formation http://purl.obolibrary.org/obo/GO_1901366 GO:1901363 biolink:MolecularActivity heterocyclic compound binding Binding to heterocyclic compound. go-plus.json http://purl.obolibrary.org/obo/GO_1901363 GO:1901364 biolink:BiologicalProcess funalenone metabolic process The chemical reactions and pathways involving funalenone. go-plus.json funalenone metabolism http://purl.obolibrary.org/obo/GO_1901364 GO:1901372 biolink:BiologicalProcess obsolete trehalose biosynthetic process involved in ascospore formation OBSOLETE. Any trehalose biosynthetic process that is involved in ascospore formation. go-plus.json trehalose biosynthesis involved in ascospore formation|mycose biosynthesis involved in ascospore biosynthesis|mycose biosynthetic process involved in ascospore biosynthesis|trehalose anabolism involved in ascospore formation|trehalose formation involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore formation|mykose biosynthetic process involved in ascospore formation|trehalose synthesis involved in ascospore formation|trehalose synthesis involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore biosynthesis|mykose biosynthetic process involved in ascospore biosynthesis|trehalose formation involved in ascospore formation|trehalose anabolism involved in ascospore biosynthesis|mycose biosynthesis involved in ascospore formation|mycose biosynthetic process involved in ascospore formation|trehalose biosynthetic process involved in ascospore biosynthesis|trehalose biosynthesis involved in ascospore biosynthesis http://purl.obolibrary.org/obo/GO_1901372 GO:1901373 biolink:BiologicalProcess lipid hydroperoxide transport The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901373 GO:1901370 biolink:BiologicalProcess response to glutathione Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901370 GO:1901371 biolink:BiologicalProcess regulation of leaf morphogenesis Any process that modulates the frequency, rate or extent of leaf morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1901371 CHEBI:9168 biolink:ChemicalSubstance sirolimus go-plus.json http://purl.obolibrary.org/obo/CHEBI_9168 chebi_ph7_3 NCBITaxon:1648028 biolink:OrganismalEntity Sorghinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648028 NCBITaxon:1648029 biolink:OrganismalEntity Tripsacinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648029 NCBITaxon:10226 biolink:OrganismalEntity Placozoa go-plus.json placozoans|placozoans|placozoan http://purl.obolibrary.org/obo/NCBITaxon_10226 NCBITaxon:10227 biolink:OrganismalEntity Trichoplax go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_10227 NCBITaxon:10228 biolink:OrganismalEntity Trichoplax adhaerens go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_10228 GO:0061590 biolink:BiologicalProcess calcium activated phosphatidylcholine scrambling The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061590 GO:1901378 biolink:BiologicalProcess organic heteropentacyclic compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound. go-plus.json organic heteropentacyclic compound anabolism|organic heteropentacyclic compound synthesis|organic heteropentacyclic compound biosynthesis|organic heteropentacyclic compound formation http://purl.obolibrary.org/obo/GO_1901378 GO:1901379 biolink:BiologicalProcess regulation of potassium ion transmembrane transport Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport. go-plus.json regulation of potassium ion membrane transport http://purl.obolibrary.org/obo/GO_1901379 GO:0061591 biolink:BiologicalProcess calcium activated galactosylceramide scrambling The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061591 GO:1901376 biolink:BiologicalProcess organic heteropentacyclic compound metabolic process The chemical reactions and pathways involving organic heteropentacyclic compound. go-plus.json organic heteropentacyclic compound metabolism http://purl.obolibrary.org/obo/GO_1901376 GO:0061592 biolink:BiologicalProcess phosphatidylserine exposure on osteoblast involved in bone mineralization A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization. go-plus.json http://purl.obolibrary.org/obo/GO_0061592 GO:1901377 biolink:BiologicalProcess organic heteropentacyclic compound catabolic process The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound. go-plus.json organic heteropentacyclic compound breakdown|organic heteropentacyclic compound catabolism|organic heteropentacyclic compound degradation http://purl.obolibrary.org/obo/GO_1901377 GO:0061593 biolink:MolecularActivity sulfoquinovose isomerase activity Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose. go-plus.json http://purl.obolibrary.org/obo/GO_0061593 NCBITaxon:1648021 biolink:OrganismalEntity Oryzinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648021 GO:1901374 biolink:BiologicalProcess acetate ester transport The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901374 GO:0061594 biolink:MolecularActivity 6-deoxy-6-sulfofructose kinase activity Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP. MetaCyc:RXN-15297|RHEA:40443|EC:2.7.1.184 go-plus.json http://purl.obolibrary.org/obo/GO_0061594 GO:1901375 biolink:MolecularActivity acetate ester transmembrane transporter activity Enables the transfer of an acetate ester from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901375 GO:0061595 biolink:MolecularActivity 6-deoxy-6-sulfofructose-1-phosphate aldolase activity Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0061595 GO:1901383 biolink:BiologicalProcess negative regulation of chorionic trophoblast cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation. go-plus.json downregulation of chorionic trophoblast cell proliferation|down regulation of chorionic trophoblast cell proliferation|inhibition of chorionic trophoblast cell proliferation|down-regulation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_1901383 GO:0061596 biolink:MolecularActivity 3-sulfolactaldehyde reductase activity Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+. MetaCyc:RXN-15299|RHEA:40511|EC:1.1.1.373 go-plus.json http://purl.obolibrary.org/obo/GO_0061596 GO:1901384 biolink:BiologicalProcess positive regulation of chorionic trophoblast cell proliferation Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation. go-plus.json up regulation of chorionic trophoblast cell proliferation|upregulation of chorionic trophoblast cell proliferation|up-regulation of chorionic trophoblast cell proliferation|activation of chorionic trophoblast cell proliferation http://purl.obolibrary.org/obo/GO_1901384 GO:0061597 biolink:MolecularActivity obsolete cyclic pyranopterin monophosphate synthase activity OBSOLETE. Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0061597 GO:0061598 biolink:MolecularActivity molybdopterin adenylyltransferase activity Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin. RHEA:31331|EC:2.7.7.75 go-plus.json http://purl.obolibrary.org/obo/GO_0061598 GO:1901381 biolink:BiologicalProcess positive regulation of potassium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. go-plus.json up-regulation of potassium ion transmembrane transport|upregulation of potassium ion transmembrane transport|up regulation of potassium ion transmembrane transport|positive regulation of potassium ion membrane transport|activation of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1901381 GO:0061599 biolink:MolecularActivity molybdopterin molybdotransferase activity Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP. EC:2.10.1.1|Reactome:R-HSA-947531|RHEA:35047 go-plus.json http://purl.obolibrary.org/obo/GO_0061599 GO:1901382 biolink:BiologicalProcess regulation of chorionic trophoblast cell proliferation Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_1901382 GO:1901380 biolink:BiologicalProcess negative regulation of potassium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport. go-plus.json down regulation of potassium ion transmembrane transport|downregulation of potassium ion transmembrane transport|negative regulation of potassium ion membrane transport|down-regulation of potassium ion transmembrane transport|inhibition of potassium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1901380 NCBITaxon:1648036 biolink:OrganismalEntity Panicodae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648036 CHEBI:145863 biolink:ChemicalSubstance PG(16:0_16:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145863 NCBITaxon:1648038 biolink:OrganismalEntity Triticodae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648038 CHEBI:36090 biolink:ChemicalSubstance 4-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36090 CHEBI:9150 biolink:ChemicalSubstance simvastatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9150 chebi_ph7_3 CHEBI:36091 biolink:ChemicalSubstance cinnamates go-plus.json http://purl.obolibrary.org/obo/CHEBI_36091 GO:1901389 biolink:BiologicalProcess negative regulation of transforming growth factor beta activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation. go-plus.json down regulation of TGF-B activation|inhibition of TGFbeta activation|inhibition of TGFB activation|down regulation of TGF-beta activation|down regulation of L-TGF-beta activation|downregulation of transforming growth factor beta activation|inhibition of TGF-B activation|downregulation of TGF-beta activation|down regulation of TGFB activation|negative regulation of latent TGF-beta activation|down-regulation of latent TGF-beta activation|downregulation of L-TGF-beta activation|down regulation of transforming growth factor beta activation|inhibition of transforming growth factor beta activation|downregulation of TGFB activation|down-regulation of TGFbeta activation|negative regulation of TGFbeta activation|negative regulation of TGF-beta activation|down-regulation of TGF-beta activation|downregulation of latent TGF-beta activation|down-regulation of L-TGF-beta activation|negative regulation of L-TGF-beta activation|negative regulation of TGF-B activation|down-regulation of TGF-B activation|down-regulation of TGFB activation|down regulation of latent TGF-beta activation|negative regulation of TGFB activation|downregulation of TGFbeta activation|down regulation of TGFbeta activation|downregulation of TGF-B activation|inhibition of TGF-beta activation|inhibition of latent TGF-beta activation|down-regulation of transforming growth factor beta activation|inhibition of L-TGF-beta activation http://purl.obolibrary.org/obo/GO_1901389 NCBITaxon:1648030 biolink:OrganismalEntity Triticinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648030 GO:1901387 biolink:BiologicalProcess positive regulation of voltage-gated calcium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity. go-plus.json activation of depolarization-activated voltage gated calcium channel activity|up regulation of voltage-sensitive calcium channel|upregulation of voltage-dependent calcium channel activity|positive regulation of depolarization-activated voltage-gated calcium channel|upregulation of depolarization-activated voltage-gated calcium channel activity|upregulation of depolarization-activated calcium channel|positive regulation of voltage-sensitive calcium channel|upregulation of voltage-gated calcium ion channel activity|up regulation of depolarization-activated voltage-gated calcium channel|up-regulation of voltage-gated calcium channel activity|activation of voltage-gated calcium channel activity|up-regulation of dihydropyridine-sensitive calcium channel activity|up-regulation of depolarization-activated voltage gated calcium channel activity|activation of voltage-sensitive calcium channel|upregulation of voltage gated calcium channel activity|up-regulation of voltage-dependent calcium channel activity|up-regulation of depolarization-activated calcium channel|activation of dihydropyridine-sensitive calcium channel activity|up regulation of depolarization-activated voltage-gated calcium channel activity|up-regulation of voltage-gated calcium ion channel activity|upregulation of depolarization-activated voltage-gated calcium channel|up-regulation of voltage-sensitive calcium channel|positive regulation of depolarization-activated voltage-gated calcium channel activity|upregulation of depolarization-activated voltage gated calcium channel activity|activation of voltage-dependent calcium channel activity|positive regulation of dihydropyridine-sensitive calcium channel activity|up-regulation of voltage gated calcium channel activity|activation of depolarization-activated calcium channel|up regulation of voltage-gated calcium channel activity|activation of voltage-gated calcium ion channel activity|up regulation of dihydropyridine-sensitive calcium channel activity|activation of depolarization-activated voltage-gated calcium channel activity|positive regulation of voltage-dependent calcium channel activity|positive regulation of depolarization-activated calcium channel|up-regulation of depolarization-activated voltage-gated calcium channel|activation of voltage gated calcium channel activity|upregulation of voltage-sensitive calcium channel|up regulation of voltage-dependent calcium channel activity|positive regulation of voltage-gated calcium ion channel activity|up regulation of depolarization-activated calcium channel|up regulation of depolarization-activated voltage gated calcium channel activity|up regulation of voltage-gated calcium ion channel activity|up-regulation of depolarization-activated voltage-gated calcium channel activity|positive regulation of depolarization-activated voltage gated calcium channel activity|upregulation of voltage-gated calcium channel activity|upregulation of dihydropyridine-sensitive calcium channel activity|positive regulation of voltage gated calcium channel activity|activation of depolarization-activated voltage-gated calcium channel|up regulation of voltage gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901387 GO:1901388 biolink:BiologicalProcess regulation of transforming growth factor beta activation Any process that modulates the frequency, rate or extent of transforming growth factor beta activation. go-plus.json regulation of TGF-beta activation|regulation of L-TGF-beta activation|regulation of TGFB activation|regulation of latent TGF-beta activation|regulation of TGFbeta activation|regulation of TGF-B activation http://purl.obolibrary.org/obo/GO_1901388 GO:1901385 biolink:BiologicalProcess regulation of voltage-gated calcium channel activity Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity. go-plus.json regulation of voltage gated calcium channel activity|regulation of depolarization-activated voltage-gated calcium channel activity|regulation of depolarization-activated voltage-gated calcium channel|regulation of depolarization-activated voltage gated calcium channel activity|regulation of dihydropyridine-sensitive calcium channel activity|regulation of voltage-dependent calcium channel activity|regulation of voltage-sensitive calcium channel|regulation of depolarization-activated calcium channel|regulation of voltage-gated calcium ion channel activity http://purl.obolibrary.org/obo/GO_1901385 NCBITaxon:1648033 biolink:OrganismalEntity Andropogonodae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1648033 GO:1901386 biolink:BiologicalProcess negative regulation of voltage-gated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity. go-plus.json downregulation of voltage gated calcium channel activity|down regulation of voltage gated calcium channel activity|inhibition of voltage-dependent calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel activity|downregulation of depolarization-activated voltage-gated calcium channel|negative regulation of voltage-sensitive calcium channel|inhibition of depolarization-activated calcium channel|inhibition of voltage-gated calcium ion channel activity|down-regulation of voltage-sensitive calcium channel|downregulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel|inhibition of depolarization-activated voltage gated calcium channel activity|down-regulation of voltage-gated calcium channel activity|down-regulation of dihydropyridine-sensitive calcium channel activity|negative regulation of dihydropyridine-sensitive calcium channel activity|inhibition of voltage gated calcium channel activity|inhibition of depolarization-activated voltage-gated calcium channel|negative regulation of voltage-dependent calcium channel activity|down-regulation of voltage-dependent calcium channel activity|negative regulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated voltage gated calcium channel activity|down-regulation of depolarization-activated voltage-gated calcium channel activity|down-regulation of depolarization-activated calcium channel|negative regulation of voltage-gated calcium ion channel activity|negative regulation of depolarization-activated calcium channel|inhibition of voltage-sensitive calcium channel|down-regulation of voltage-gated calcium ion channel activity|downregulation of voltage-gated calcium channel activity|downregulation of dihydropyridine-sensitive calcium channel activity|downregulation of depolarization-activated voltage gated calcium channel activity|negative regulation of voltage gated calcium channel activity|down-regulation of voltage gated calcium channel activity|down regulation of voltage-gated calcium channel activity|down regulation of dihydropyridine-sensitive calcium channel activity|downregulation of voltage-dependent calcium channel activity|inhibition of voltage-gated calcium channel activity|down regulation of voltage-sensitive calcium channel|downregulation of depolarization-activated calcium channel|downregulation of voltage-gated calcium ion channel activity|negative regulation of depolarization-activated voltage-gated calcium channel|down-regulation of depolarization-activated voltage-gated calcium channel|downregulation of voltage-sensitive calcium channel|inhibition of depolarization-activated voltage-gated calcium channel activity|down regulation of voltage-dependent calcium channel activity|negative regulation of depolarization-activated voltage gated calcium channel activity|down-regulation of depolarization-activated voltage gated calcium channel activity|down regulation of voltage-gated calcium ion channel activity|down regulation of depolarization-activated calcium channel|inhibition of dihydropyridine-sensitive calcium channel activity http://purl.obolibrary.org/obo/GO_1901386 GO:1901394 biolink:BiologicalProcess positive regulation of transforming growth factor beta1 activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation. go-plus.json up regulation of TGFB1 activation|up regulation of transforming growth factor-beta1 activation|upregulation of L-TGF-beta 1 activation|up-regulation of latent-TGF-beta1 activation|positive regulation of transforming growth factor-beta1 activation|upregulation of transforming growth factor beta1 activation|up-regulation of TGFbeta 1 activation|activation of transforming growth factor-beta1 activation|up regulation of TGF-beta 1 activation|upregulation of TGFB1 activation|upregulation of latent-TGF-beta1 activation|up regulation of L-TGF-beta 1 activation|positive regulation of TGF-beta 1 activation|activation of TGFbeta 1 activation|positive regulation of L-TGF-beta 1 activation|up-regulation of transforming growth factor-beta1 activation|up regulation of transforming growth factor beta1 activation|activation of transforming growth factor beta1 activation|positive regulation of TGFbeta 1 activation|activation of TGF-beta 1 activation|activation of L-TGF-beta 1 activation|up regulation of TGFbeta 1 activation|up-regulation of TGFB1 activation|up regulation of latent-TGF-beta1 activation|positive regulation of latent-TGF-beta1 activation|up-regulation of TGF-beta 1 activation|upregulation of transforming growth factor-beta1 activation|up-regulation of L-TGF-beta 1 activation|activation of TGFB1 activation|up-regulation of transforming growth factor beta1 activation|activation of latent-TGF-beta1 activation|upregulation of TGFbeta 1 activation|positive regulation of TGFB1 activation|upregulation of TGF-beta 1 activation http://purl.obolibrary.org/obo/GO_1901394 GO:0036530 biolink:BiologicalProcess protein deglycation, methylglyoxal removal The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein. go-plus.json protein deglycation of methylglyoxal-glycated protein http://purl.obolibrary.org/obo/GO_0036530 GO:0036531 biolink:BiologicalProcess glutathione deglycation The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine. go-plus.json http://purl.obolibrary.org/obo/GO_0036531 GO:1901395 biolink:BiologicalProcess regulation of transforming growth factor beta2 activation Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation. go-plus.json regulation of TGF-beta 2 activation|regulation of TGFB2 activation|regulation of TGFbeta 2 activation http://purl.obolibrary.org/obo/GO_1901395 GO:1901392 biolink:BiologicalProcess regulation of transforming growth factor beta1 activation Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation. go-plus.json regulation of TGF-beta 1 activation|regulation of TGFB1 activation|regulation of L-TGF-beta 1 activation|regulation of latent-TGF-beta1 activation|regulation of TGFbeta 1 activation|regulation of transforming growth factor-beta1 activation http://purl.obolibrary.org/obo/GO_1901392 GO:1901393 biolink:BiologicalProcess negative regulation of transforming growth factor beta1 activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation. go-plus.json down regulation of TGF-beta 1 activation|down regulation of L-TGF-beta 1 activation|downregulation of TGFB1 activation|downregulation of TGF-beta 1 activation|inhibition of latent-TGF-beta1 activation|down-regulation of transforming growth factor-beta1 activation|down regulation of transforming growth factor beta1 activation|negative regulation of transforming growth factor-beta1 activation|down regulation of TGFB1 activation|downregulation of L-TGF-beta 1 activation|downregulation of transforming growth factor beta1 activation|down-regulation of TGFbeta 1 activation|negative regulation of TGFbeta 1 activation|down regulation of latent-TGF-beta1 activation|inhibition of TGFB1 activation|negative regulation of TGF-beta 1 activation|down-regulation of TGF-beta 1 activation|down-regulation of L-TGF-beta 1 activation|negative regulation of L-TGF-beta 1 activation|downregulation of latent-TGF-beta1 activation|inhibition of transforming growth factor-beta1 activation|down-regulation of transforming growth factor beta1 activation|downregulation of TGFbeta 1 activation|down regulation of TGFbeta 1 activation|down regulation of transforming growth factor-beta1 activation|down-regulation of TGFB1 activation|inhibition of transforming growth factor beta1 activation|down-regulation of latent-TGF-beta1 activation|negative regulation of latent-TGF-beta1 activation|negative regulation of TGFB1 activation|inhibition of TGF-beta 1 activation|inhibition of L-TGF-beta 1 activation|downregulation of transforming growth factor-beta1 activation|inhibition of TGFbeta 1 activation http://purl.obolibrary.org/obo/GO_1901393 GO:1901390 biolink:BiologicalProcess positive regulation of transforming growth factor beta activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation. go-plus.json up-regulation of transforming growth factor beta activation|activation of transforming growth factor beta activation|activation of TGFB activation|positive regulation of TGF-B activation|up-regulation of TGF-beta activation|up-regulation of L-TGF-beta activation|up regulation of TGF-B activation|upregulation of latent TGF-beta activation|up-regulation of TGFB activation|upregulation of TGFbeta activation|upregulation of TGF-beta activation|up-regulation of latent TGF-beta activation|upregulation of L-TGF-beta activation|upregulation of TGF-B activation|up regulation of transforming growth factor beta activation|upregulation of TGFB activation|up-regulation of TGFbeta activation|activation of latent TGF-beta activation|up regulation of TGF-beta activation|up-regulation of TGF-B activation|up regulation of L-TGF-beta activation|activation of TGFbeta activation|positive regulation of latent TGF-beta activation|upregulation of transforming growth factor beta activation|positive regulation of TGF-beta activation|positive regulation of L-TGF-beta activation|up regulation of latent TGF-beta activation|up regulation of TGFB activation|activation of TGF-beta activation|activation of TGF-B activation|positive regulation of TGFB activation|positive regulation of TGFbeta activation|activation of L-TGF-beta activation|up regulation of TGFbeta activation http://purl.obolibrary.org/obo/GO_1901390 CHEBI:36085 biolink:ChemicalSubstance trihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36085 CHEBI:36086 biolink:ChemicalSubstance sulfonatobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36086 CHEBI:36084 biolink:ChemicalSubstance dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36084 CHEBI:36087 biolink:ChemicalSubstance cinnamate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_36087 CHEBI:36088 biolink:ChemicalSubstance thromboxanes A go-plus.json http://purl.obolibrary.org/obo/CHEBI_36088 chebi_ph7_3 CHEBI:145850 biolink:ChemicalSubstance PE(20:3_20:3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145850 CHEBI:145852 biolink:ChemicalSubstance PE(18:4_22:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145852 CHEBI:9160 biolink:ChemicalSubstance single-stranded DNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_9160 CHEBI:145855 biolink:ChemicalSubstance phosphatidylethanolamine 44:8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145855 CHEBI:145856 biolink:ChemicalSubstance PE(22:2_22:6) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145856 GO:0036527 biolink:BiologicalProcess peptidyl-arginine deglycation The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein. go-plus.json deglycation of N-acetylarginine http://purl.obolibrary.org/obo/GO_0036527 GO:0036528 biolink:BiologicalProcess peptidyl-lysine deglycation The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein. go-plus.json deglycation of N-acetyllysine http://purl.obolibrary.org/obo/GO_0036528 GO:0036529 biolink:BiologicalProcess protein deglycation, glyoxal removal The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein. go-plus.json protein deglycation of glyoxal-glycated protein http://purl.obolibrary.org/obo/GO_0036529 GO:1901398 biolink:BiologicalProcess regulation of transforming growth factor beta3 activation Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation. go-plus.json regulation of TGF-beta 3 activation|regulation of TGFB3 activation|regulation of TGFbeta 3 activation http://purl.obolibrary.org/obo/GO_1901398 GO:1901399 biolink:BiologicalProcess negative regulation of transforming growth factor beta3 activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation. go-plus.json inhibition of TGFbeta 3 activation|down regulation of TGF-beta 3 activation|downregulation of TGFB3 activation|down regulation of transforming growth factor beta3 activation|downregulation of TGF-beta 3 activation|down regulation of TGFB3 activation|downregulation of transforming growth factor beta3 activation|down-regulation of TGFbeta 3 activation|negative regulation of TGFbeta 3 activation|inhibition of TGFB3 activation|down-regulation of TGF-beta 3 activation|negative regulation of TGF-beta 3 activation|down-regulation of transforming growth factor beta3 activation|downregulation of TGFbeta 3 activation|down regulation of TGFbeta 3 activation|inhibition of transforming growth factor beta3 activation|negative regulation of TGFB3 activation|down-regulation of TGFB3 activation|inhibition of TGF-beta 3 activation http://purl.obolibrary.org/obo/GO_1901399 GO:1901396 biolink:BiologicalProcess negative regulation of transforming growth factor beta2 activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation. go-plus.json inhibition of TGFbeta 2 activation|down regulation of TGF-beta 2 activation|downregulation of TGFB2 activation|down regulation of transforming growth factor beta2 activation|downregulation of TGF-beta 2 activation|down regulation of TGFB2 activation|downregulation of transforming growth factor beta2 activation|negative regulation of TGFbeta 2 activation|down-regulation of TGFbeta 2 activation|inhibition of TGFB2 activation|down-regulation of TGF-beta 2 activation|negative regulation of TGF-beta 2 activation|down-regulation of transforming growth factor beta2 activation|downregulation of TGFbeta 2 activation|inhibition of transforming growth factor beta2 activation|down regulation of TGFbeta 2 activation|negative regulation of TGFB2 activation|down-regulation of TGFB2 activation|inhibition of TGF-beta 2 activation http://purl.obolibrary.org/obo/GO_1901396 GO:1901397 biolink:BiologicalProcess positive regulation of transforming growth factor beta2 activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation. go-plus.json positive regulation of TGFB2 activation|upregulation of TGF-beta 2 activation|up regulation of TGFB2 activation|upregulation of transforming growth factor beta2 activation|up-regulation of TGFbeta 2 activation|up regulation of TGF-beta 2 activation|upregulation of TGFB2 activation|activation of TGFbeta 2 activation|positive regulation of TGF-beta 2 activation|up regulation of transforming growth factor beta2 activation|activation of transforming growth factor beta2 activation|positive regulation of TGFbeta 2 activation|activation of TGF-beta 2 activation|up regulation of TGFbeta 2 activation|up-regulation of TGFB2 activation|up-regulation of TGF-beta 2 activation|activation of TGFB2 activation|up-regulation of transforming growth factor beta2 activation|upregulation of TGFbeta 2 activation http://purl.obolibrary.org/obo/GO_1901397 GO:0036520 biolink:BiologicalProcess astrocyte-dopaminergic neuron signaling Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron. go-plus.json mesencephalic dopaminergic neuron-astrocyte crosstalk|dopaminergic neuron-astrocyte crosstalk|astrocyte-dopaminergic neuron cell signaling|midbrain dopaminergic neuron-astrocyte crosstalk http://purl.obolibrary.org/obo/GO_0036520 GO:0036521 biolink:BiologicalProcess modulation by symbiont of host protein localization to phagocytic vesicle Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host protein localisation to phagosome http://purl.obolibrary.org/obo/GO_0036521 GO:0036522 biolink:BiologicalProcess negative regulation by symbiont of host protein localization to phagocytic vesicle Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json inhibition of host protein localisation to phagosome|suppression of host protein localisation to phagosome|disruption of host protein localisation to phagosome http://purl.obolibrary.org/obo/GO_0036522 GO:0036523 biolink:BiologicalProcess obsolete induction by symbiont of host cytokine production OBSOLETE. Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host cytokine secretion|'induction by symbiont of host cytokine secretion'|induction by symbiont of host cytokine secretion http://purl.obolibrary.org/obo/GO_0036523 GO:0036524 biolink:MolecularActivity protein deglycase activity Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein. MetaCyc:RXN-17634|MetaCyc:RXN-17632|MetaCyc:RXN-17630 go-plus.json protein deglycating enzyme http://purl.obolibrary.org/obo/GO_0036524 GO:0036525 biolink:BiologicalProcess protein deglycation The removal of a sugar or dicarbonyl from a glycated protein. go-plus.json glycated protein repair http://purl.obolibrary.org/obo/GO_0036525 GO:0036526 biolink:BiologicalProcess peptidyl-cysteine deglycation The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein. go-plus.json deglycation of N-acetylcysteine http://purl.obolibrary.org/obo/GO_0036526 CHEBI:36096 biolink:ChemicalSubstance cyclohexanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36096 CHEBI:36094 biolink:ChemicalSubstance organic chloride salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_36094 CHEBI:61032 biolink:ChemicalSubstance 5,6,7,8-tetrahydropterin-6-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61032 chebi_ph7_3 CHEBI:85004 biolink:ChemicalSubstance sphingadienine-1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85004 CHEBI:85005 biolink:ChemicalSubstance anticapsin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85005 CHEBI:85006 biolink:ChemicalSubstance N(1),N(8)-bis(sinapoyl)-spermidine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85006 chebi_ph7_3 CHEBI:85007 biolink:ChemicalSubstance N(1),N(8)-bis(coumaroyl)spermidine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85007 chebi_ph7_3 CHEBI:61036 biolink:ChemicalSubstance 7-carboxylato-7-deazaguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61036 chebi_ph7_3 CHEBI:85008 biolink:ChemicalSubstance trans-4-coumaroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85008 chebi_ph7_3 CHEBI:26706 biolink:ChemicalSubstance sn-glycerol 3-phosphates go-plus.json http://purl.obolibrary.org/obo/CHEBI_26706 CHEBI:26707 biolink:ChemicalSubstance glycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26707 CHEBI:26708 biolink:ChemicalSubstance sodium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_26708 chebi_ph7_3 CHEBI:26712 biolink:ChemicalSubstance sodium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_26712 CHEBI:75688 biolink:ChemicalSubstance 1,3-dipalmitoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75688 chebi_ph7_3 CHEBI:26714 biolink:ChemicalSubstance sodium salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_26714 PR:000013883 biolink:Protein renin A protein that is a translation product of the human REN gene or a 1:1 ortholog thereof. go-plus.json angiotensinogenase|REN http://purl.obolibrary.org/obo/PR_000013883 CHEBI:61042 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61042 chebi_ph7_3 CHEBI:61049 biolink:ChemicalSubstance tacrolimus (anhydrous) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61049 chebi_ph7_3 CHEBI:61048 biolink:ChemicalSubstance ganglioside GM1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61048 CHEBI:9192 biolink:ChemicalSubstance solavetivone go-plus.json http://purl.obolibrary.org/obo/CHEBI_9192 chebi_ph7_3 NCBITaxon:10239 biolink:OrganismalEntity Viruses go-plus.json Vira|Viridae|viruses http://purl.obolibrary.org/obo/NCBITaxon_10239 CHEBI:61050 biolink:ChemicalSubstance alkyl hydroperoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61050 CHEBI:61051 biolink:ChemicalSubstance lipid hydroperoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61051 chebi_ph7_3 CHEBI:61057 biolink:ChemicalSubstance tacrolimus hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61057 CHEBI:85027 biolink:ChemicalSubstance 2'-phospho-nucleotide 5'-phosphate(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85027 chebi_ph7_3 CHEBI:566789 biolink:ChemicalSubstance ethylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_566789 chebi_ph7_3 GO:0061500 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061500 GO:0061501 biolink:MolecularActivity 2',3'-cyclic GMP-AMP synthase activity Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP). RHEA:42064|Reactome:R-HSA-3244614|EC:2.7.7.86 go-plus.json 2',3' cyclic-GMP-AMP synthase activity|cyclic-GMP-AMP synthase activity|cyclic 2',3' GAMP synthase activity|2',3' cyclic GMP-AMP synthase activity http://purl.obolibrary.org/obo/GO_0061501 GO:0061502 biolink:BiologicalProcess early endosome to recycling endosome transport The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0061502 CHEBI:75690 biolink:ChemicalSubstance (8R)-hydroxy-(11R,12R)-epoxyicosa-(5Z,9E,14Z)-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75690 GO:0061503 biolink:MolecularActivity tRNA threonylcarbamoyladenosine dehydratase Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A. go-plus.json http://purl.obolibrary.org/obo/GO_0061503 GO:0061504 biolink:BiologicalProcess cyclic threonylcarbamoyladenosine biosynthetic process The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0061504 GO:0061505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061505 GO:0061506 biolink:MolecularActivity obsolete DNA topoisomerase type II (ATP-independent) activity OBSOLETE. Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. go-plus.json http://purl.obolibrary.org/obo/GO_0061506 GO:0061507 biolink:MolecularActivity 2',3'-cyclic GMP-AMP binding Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages. go-plus.json 2',3' cyclic GAMP binding|2',5-3',5'-cyclic GMP-AMP binding|2',3' cGAMP binding|2',3'-cyclic GAMP binding|cyclic-GMP-AMP binding|2',3'-cGAMP binding|c[G(2',5')pA(3',5')p] binding http://purl.obolibrary.org/obo/GO_0061507 GO:0061508 biolink:BiologicalProcess CDP phosphorylation The process of introducing a phosphate group into CDP to produce a CTP. go-plus.json http://purl.obolibrary.org/obo/GO_0061508 CHEBI:75692 biolink:ChemicalSubstance (8R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,9E,14Z)-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75692 GO:0061509 biolink:BiologicalProcess asymmetric protein localization to old mitotic spindle pole body Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically. go-plus.json http://purl.obolibrary.org/obo/GO_0061509 CHEBI:75696 biolink:ChemicalSubstance (10R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,8Z,14Z)-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75696 CHEBI:85011 biolink:ChemicalSubstance EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85011 CHEBI:85040 biolink:ChemicalSubstance (3R)-3,6-diaminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85040 CHEBI:61073 biolink:ChemicalSubstance oxygen radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_61073 CHEBI:61078 biolink:ChemicalSubstance purine nucleoside bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61078 CHEBI:61079 biolink:ChemicalSubstance ribonucleoside bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61079 CHEBI:85046 biolink:ChemicalSubstance skin lightening agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_85046 CHEBI:85048 biolink:ChemicalSubstance EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85048 CHEBI:85049 biolink:ChemicalSubstance EC 1.10.3.1 (catechol oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85049 GO:0061520 biolink:BiologicalProcess Langerhans cell differentiation The process in which a precursor cell type acquires the specialized features of a Langerhans cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061520 GO:0061521 biolink:BiologicalProcess hepatic stellate cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061521 GO:0061522 biolink:MolecularActivity 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA. go-plus.json http://purl.obolibrary.org/obo/GO_0061522 GO:0061523 biolink:BiologicalProcess cilium disassembly A cellular process that results in the breakdown of a cilium. go-plus.json cilium resorption http://purl.obolibrary.org/obo/GO_0061523 GO:0061524 biolink:BiologicalProcess central canal development The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0061524 GO:0061525 biolink:BiologicalProcess hindgut development The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut. go-plus.json http://purl.obolibrary.org/obo/GO_0061525 GO:0061526 biolink:BiologicalProcess acetylcholine secretion The regulated release of acetylcholine by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061526 GO:0061527 biolink:BiologicalProcess dopamine secretion, neurotransmission The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061527 GO:0061528 biolink:BiologicalProcess aspartate secretion The regulated release of aspartate by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061528 GO:0061529 biolink:BiologicalProcess epinephrine secretion, neurotransmission The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter. go-plus.json adrenaline secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061529 CHEBI:61081 biolink:ChemicalSubstance bis(5'-nucleosidyl) oliogophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61081 CHEBI:61082 biolink:ChemicalSubstance lipid-linked peptidoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_61082 CHEBI:61085 biolink:ChemicalSubstance 3-sulfino-L-alanine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61085 chebi_ph7_3 CHEBI:85033 biolink:ChemicalSubstance cobalt(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85033 chebi_ph7_3 CHEBI:85035 biolink:ChemicalSubstance methyl-Co(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85035 chebi_ph7_3 GO:0061510 biolink:BiologicalProcess asymmetric protein localization to new mitotic spindle pole body Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically. go-plus.json http://purl.obolibrary.org/obo/GO_0061510 GO:0061511 biolink:BiologicalProcess centriole elongation The centrosome organization process by which a centriole increases in length as part of the process of replication. go-plus.json http://purl.obolibrary.org/obo/GO_0061511 GO:0061512 biolink:BiologicalProcess protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a cilium. go-plus.json http://purl.obolibrary.org/obo/GO_0061512 GO:0061513 biolink:MolecularActivity glucose 6-phosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out). Reactome:R-HSA-3229118|Reactome:R-HSA-198513|Reactome:R-HSA-3257122 go-plus.json glucose 6-phosphate:phosphate antiporter activity http://purl.obolibrary.org/obo/GO_0061513 GO:0061514 biolink:BiologicalProcess interleukin-34-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0061514 GO:0061515 biolink:BiologicalProcess myeloid cell development The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061515 GO:0061516 biolink:BiologicalProcess monocyte proliferation The expansion of a monocyte population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0061516 GO:0061517 biolink:BiologicalProcess macrophage proliferation The expansion of a macrophage population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0061517 GO:0061518 biolink:BiologicalProcess microglial cell proliferation The expansion of a microglial cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0061518 GO:0061519 biolink:BiologicalProcess macrophage homeostasis The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061519 GO:1901309 biolink:BiologicalProcess negative regulation of sterol regulatory element binding protein cleavage Any process that stops, prevents or reduces the frequency, rate or extent of sterol regulatory element binding protein cleavage. go-plus.json downregulation of SREBP cleavage|down regulation of sterol regulatory element binding protein cleavage|inhibition of sterol regulatory element binding protein cleavage|down regulation of SREBP cleavage|inhibition of SREBP processing|inhibition of SREBP cleavage|down-regulation of sterol regulatory element binding protein cleavage|down-regulation of SREBP cleavage|negative regulation of SREBP cleavage|downregulation of sterol regulatory element binding protein cleavage http://purl.obolibrary.org/obo/GO_1901309 GO:1901307 biolink:BiologicalProcess positive regulation of spermidine biosynthetic process Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process. go-plus.json up regulation of spermidine synthesis|positive regulation of spermidine formation|activation of spermidine biosynthesis|up regulation of spermidine formation|upregulation of spermidine anabolism|up-regulation of spermidine biosynthetic process|up-regulation of spermidine biosynthesis|upregulation of spermidine synthesis|upregulation of spermidine formation|up-regulation of spermidine anabolism|upregulation of spermidine biosynthesis|upregulation of spermidine biosynthetic process|up-regulation of spermidine synthesis|activation of spermidine anabolism|up-regulation of spermidine formation|activation of spermidine synthesis|positive regulation of spermidine anabolism|up regulation of spermidine biosynthetic process|up regulation of spermidine biosynthesis|up regulation of spermidine anabolism|activation of spermidine formation|positive regulation of spermidine biosynthesis|activation of spermidine biosynthetic process|positive regulation of spermidine synthesis http://purl.obolibrary.org/obo/GO_1901307 GO:1901308 biolink:BiologicalProcess regulation of sterol regulatory element binding protein cleavage Any process that modulates the frequency, rate or extent of sterol regulatory element binding protein cleavage. go-plus.json regulation of SREBP cleavage http://purl.obolibrary.org/obo/GO_1901308 GO:1901305 biolink:BiologicalProcess negative regulation of spermidine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process. go-plus.json negative regulation of spermidine biosynthesis|down-regulation of spermidine biosynthesis|down-regulation of spermidine biosynthetic process|downregulation of spermidine synthesis|down regulation of spermidine anabolism|downregulation of spermidine formation|down regulation of spermidine synthesis|inhibition of spermidine biosynthetic process|inhibition of spermidine anabolism|down regulation of spermidine formation|inhibition of spermidine biosynthesis|inhibition of spermidine synthesis|inhibition of spermidine formation|down regulation of spermidine biosynthesis|down regulation of spermidine biosynthetic process|down-regulation of spermidine anabolism|negative regulation of spermidine anabolism|downregulation of spermidine biosynthetic process|downregulation of spermidine biosynthesis|negative regulation of spermidine synthesis|down-regulation of spermidine synthesis|down-regulation of spermidine formation|negative regulation of spermidine formation|downregulation of spermidine anabolism http://purl.obolibrary.org/obo/GO_1901305 GO:1901303 biolink:BiologicalProcess negative regulation of cargo loading into COPII-coated vesicle Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle. go-plus.json negative regulation of COPII coat-cargo complex assembly|down-regulation of COPII coat-cargo complex assembly|down-regulation of cargo selection into COPII-coated vesicle|negative regulation of cargo selection into COPII-coated vesicle|down regulation of cargo loading into COPII-coated vesicle|down-regulation of cargo loading into COPII vesicle|downregulation of cargo loading into COPII-coated vesicle|negative regulation of cargo loading into COPII vesicle|inhibition of COPII coat-cargo complex assembly|inhibition of COPII vesicle protein binding|inhibition of cargo selection into COPII-coated vesicle|downregulation of cargo loading into COPII vesicle|down-regulation of cargo loading into COPII-coated vesicle|inhibition of protein sorting into COPII-coated vesicles|down regulation of COPII coat-cargo complex assembly|down regulation of cargo selection into COPII-coated vesicle|down regulation of cargo loading into COPII vesicle|downregulation of COPII coat-cargo complex assembly|downregulation of cargo selection into COPII-coated vesicle|inhibition of cargo loading into COPII-coated vesicle|inhibition of cargo loading into COPII vesicle http://purl.obolibrary.org/obo/GO_1901303 GO:1901304 biolink:BiologicalProcess regulation of spermidine biosynthetic process Any process that modulates the frequency, rate or extent of spermidine biosynthetic process. go-plus.json regulation of spermidine anabolism|regulation of spermidine synthesis|regulation of spermidine formation|regulation of spermidine biosynthesis http://purl.obolibrary.org/obo/GO_1901304 GO:1901301 biolink:BiologicalProcess regulation of cargo loading into COPII-coated vesicle Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle. go-plus.json regulation of cargo loading into COPII vesicle|regulation of COPII coat-cargo complex assembly|regulation of cargo selection into COPII-coated vesicle http://purl.obolibrary.org/obo/GO_1901301 GO:1901300 biolink:BiologicalProcess positive regulation of hydrogen peroxide-mediated programmed cell death Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. go-plus.json up-regulation of hydrogen peroxide-mediated programmed cell death|activation of hydrogen peroxide-mediated programmed cell death|up regulation of hydrogen peroxide-mediated programmed cell death|upregulation of hydrogen peroxide-mediated programmed cell death http://purl.obolibrary.org/obo/GO_1901300 GO:0061540 biolink:BiologicalProcess octopamine secretion, neurotransmission The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061540 GO:0061541 biolink:BiologicalProcess rhabdomere morphogenesis The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments. go-plus.json http://purl.obolibrary.org/obo/GO_0061541 GO:0061542 biolink:MolecularActivity 3-demethylubiquinol-n 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n. go-plus.json 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase|5-demethylubiquinone-9 methyltransferase|S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase|5-demethylubiquinone-10 methyltransferase|OMHMB-methyltransferase http://purl.obolibrary.org/obo/GO_0061542 GO:0061543 biolink:MolecularActivity 3-demethylubiquinol-6 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6. go-plus.json http://purl.obolibrary.org/obo/GO_0061543 GO:0061544 biolink:BiologicalProcess peptide secretion, neurotransmission The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061544 GO:0061545 biolink:BiologicalProcess tyramine secretion The regulated release of a tyramine by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061545 GO:0061546 biolink:BiologicalProcess tyramine secretion, neurotransmission The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061546 GO:0061547 biolink:MolecularActivity glycogen synthase activity, transferring glucose-1-phosphate Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate. Reactome:R-HSA-3781024|Reactome:R-HSA-3780994 go-plus.json http://purl.obolibrary.org/obo/GO_0061547 GO:0061548 biolink:BiologicalProcess ganglion development The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. go-plus.json gangliogenesis|ganglia development http://purl.obolibrary.org/obo/GO_0061548 GO:0061549 biolink:BiologicalProcess sympathetic ganglion development The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. go-plus.json sympathetic ganglia development http://purl.obolibrary.org/obo/GO_0061549 GO:1901318 biolink:BiologicalProcess negative regulation of flagellated sperm motility Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. go-plus.json down regulation of sperm motility|negative regulation of sperm motility|downregulation of sperm movement|down regulation of sperm movement|inhibition of sperm movement|down-regulation of sperm motility|inhibition of sperm motility|downregulation of sperm motility|negative regulation of sperm movement|down-regulation of sperm movement http://purl.obolibrary.org/obo/GO_1901318 GO:1901319 biolink:BiologicalProcess positive regulation of trehalose catabolic process Any process that activates or increases the frequency, rate or extent of trehalose catabolic process. go-plus.json positive regulation of trehalose breakdown|activation of trehalose degradation|up regulation of trehalose catabolic process|positive regulation of mykose catabolic process|activation of trehalose catabolism|activation of trehalose catabolic process|up regulation of mykose catabolic process|upregulation of mycose catabolism|activation of trehalose breakdown|up-regulation of trehalose degradation|upregulation of mycose catabolic process|up regulation of mykose catabolism|positive regulation of trehalose catabolism|positive regulation of mykose catabolism|up regulation of trehalose catabolism|up-regulation of trehalose breakdown|activation of mykose catabolism|up regulation of mycose catabolism|upregulation of mykose catabolic process|up-regulation of trehalose catabolic process|upregulation of trehalose degradation|up-regulation of mycose catabolic process|positive regulation of mycose catabolism|upregulation of trehalose catabolism|up-regulation of mykose catabolism|upregulation of trehalose breakdown|activation of mycose catabolic process|activation of mycose catabolism|up-regulation of mykose catabolic process|upregulation of trehalose catabolic process|up regulation of trehalose degradation|positive regulation of trehalose degradation|positive regulation of mycose catabolic process|up-regulation of mycose catabolism|up regulation of mycose catabolic process|upregulation of mykose catabolism|up-regulation of trehalose catabolism|up regulation of trehalose breakdown|activation of mykose catabolic process http://purl.obolibrary.org/obo/GO_1901319 GO:1901316 biolink:BiologicalProcess positive regulation of histone H2A K63-linked ubiquitination Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination. go-plus.json upregulation of histone H2A K63-linked ubiquitination|up regulation of histone H2A K63-linked ubiquitination|activation of histone H2A K63-linked ubiquitination|up-regulation of histone H2A K63-linked ubiquitination http://purl.obolibrary.org/obo/GO_1901316 CHEBI:85050 biolink:ChemicalSubstance EC 1.10.3.2 (laccase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85050 GO:1901317 biolink:BiologicalProcess regulation of flagellated sperm motility Any process that modulates the frequency, rate or extent of flagellated sperm motility. go-plus.json regulation of sperm movement|regulation of sperm motility http://purl.obolibrary.org/obo/GO_1901317 CHEBI:85051 biolink:ChemicalSubstance EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85051 CHEBI:85052 biolink:ChemicalSubstance EC 1.4.3.3 (D-amino-acid oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85052 GO:1901314 biolink:BiologicalProcess regulation of histone H2A K63-linked ubiquitination Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_1901314 GO:1901315 biolink:BiologicalProcess negative regulation of histone H2A K63-linked ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination. go-plus.json down regulation of histone H2A K63-linked ubiquitination|downregulation of histone H2A K63-linked ubiquitination|down-regulation of histone H2A K63-linked ubiquitination|inhibition of histone H2A K63-linked ubiquitination http://purl.obolibrary.org/obo/GO_1901315 GO:1901312 biolink:BiologicalProcess obsolete negative regulation of gene expression involved in extracellular matrix organization OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of gene expression involved in extracellular matrix organization. go-plus.json down regulation of extracellular matrix protein production|downregulation of gene expression involved in extracellular matrix organization|down regulation of expression of extracellular matrix proteins|downregulation of extracellular matrix protein production|downregulation of expression of extracellular matrix proteins|down-regulation of gene expression involved in extracellular matrix organization|down-regulation of extracellular matrix protein production|negative regulation of extracellular matrix protein production|down-regulation of expression of extracellular matrix proteins|negative regulation of expression of extracellular matrix proteins|inhibition of gene expression involved in extracellular matrix organization|inhibition of extracellular matrix protein production|inhibition of expression of extracellular matrix proteins|down regulation of gene expression involved in extracellular matrix organization http://purl.obolibrary.org/obo/GO_1901312 GO:1901313 biolink:BiologicalProcess obsolete positive regulation of gene expression involved in extracellular matrix organization OBSOLETE. Any process that activates or increases the frequency, rate or extent of gene expression involved in extracellular matrix organization. go-plus.json upregulation of expression of extracellular matrix proteins|up regulation of gene expression involved in extracellular matrix organization|activation of gene expression involved in extracellular matrix organization|up regulation of extracellular matrix protein production|positive regulation of extracellular matrix protein production|up regulation of expression of extracellular matrix proteins|positive regulation of expression of extracellular matrix proteins|activation of extracellular matrix protein production|activation of expression of extracellular matrix proteins|up-regulation of gene expression involved in extracellular matrix organization|up-regulation of extracellular matrix protein production|up-regulation of expression of extracellular matrix proteins|upregulation of gene expression involved in extracellular matrix organization|upregulation of extracellular matrix protein production http://purl.obolibrary.org/obo/GO_1901313 GO:1901310 biolink:BiologicalProcess positive regulation of sterol regulatory element binding protein cleavage Any process that activates or increases the frequency, rate or extent of sterol regulatory element binding protein cleavage. go-plus.json activation of SREBP cleavage|up regulation of sterol regulatory element binding protein cleavage|positive regulation of SREBP cleavage|up regulation of SREBP cleavage|upregulation of sterol regulatory element binding protein cleavage|upregulation of SREBP cleavage|up-regulation of sterol regulatory element binding protein cleavage|activation of sterol regulatory element binding protein cleavage|up-regulation of SREBP cleavage http://purl.obolibrary.org/obo/GO_1901310 GO:1901311 biolink:BiologicalProcess obsolete regulation of gene expression involved in extracellular matrix organization OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression involved in extracellular matrix organization. go-plus.json regulation of extracellular matrix protein production|regulation of expression of extracellular matrix proteins http://purl.obolibrary.org/obo/GO_1901311 CHEBI:85057 biolink:ChemicalSubstance 2-methylhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85057 CHEBI:85058 biolink:ChemicalSubstance 12-methyloctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85058 CHEBI:85059 biolink:ChemicalSubstance 3-methylundecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85059 GO:0061530 biolink:BiologicalProcess aspartate secretion, neurotransmission The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061530 GO:0061531 biolink:BiologicalProcess primary amine secretion The regulated release of a primary amine by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061531 GO:0061532 biolink:BiologicalProcess primary amine secretion, neurotransmission The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061532 GO:0061533 biolink:BiologicalProcess norepinephrine secretion, neurotransmission The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter. go-plus.json noradrenaline secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061533 GO:0061534 biolink:BiologicalProcess gamma-aminobutyric acid secretion, neurotransmission The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061534 GO:0061535 biolink:BiologicalProcess glutamate secretion, neurotransmission The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061535 GO:0061536 biolink:BiologicalProcess glycine secretion The controlled release of glycine by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061536 GO:0061537 biolink:BiologicalProcess glycine secretion, neurotransmission The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061537 GO:0061538 biolink:BiologicalProcess histamine secretion, neurotransmission The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061538 GO:0061539 biolink:BiologicalProcess octopamine secretion The controlled release of octopamine by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061539 CHEBI:51625 biolink:ChemicalSubstance indolinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51625 CHEBI:26666 biolink:ChemicalSubstance short-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26666 CHEBI:26667 biolink:ChemicalSubstance sialic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26667 CHEBI:26660 biolink:ChemicalSubstance sesterterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26660 NCBITaxon:10090 biolink:OrganismalEntity Mus musculus go-plus.json mouse|house mouse http://purl.obolibrary.org/obo/NCBITaxon_10090 CHEBI:75603 biolink:ChemicalSubstance EC 6.* (ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75603 CHEBI:51614 biolink:ChemicalSubstance diarylmethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_51614 CHEBI:75600 biolink:ChemicalSubstance EC 6.3.* (C-N bond-forming ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75600 CHEBI:75606 biolink:ChemicalSubstance hydroxamic acid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_75606 chebi_ph7_3 CHEBI:26675 biolink:ChemicalSubstance silicic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26675 chebi_ph7_3 CHEBI:26677 biolink:ChemicalSubstance silicon molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_26677 CHEBI:75604 biolink:ChemicalSubstance EC 6.4.* (C-C bond-forming ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75604 CHEBI:26672 biolink:ChemicalSubstance siderophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_26672 CHEBI:26673 biolink:ChemicalSubstance organosilanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26673 CHEBI:75608 biolink:ChemicalSubstance 2-palmitoyloxypalmityl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75608 chebi_ph7_3 CHEBI:75609 biolink:ChemicalSubstance 1-alpha-linolenoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75609 chebi_ph7_3 UBERON:0013636 biolink:AnatomicalEntity epithelium of intestinal villus A epithelium that is part of a intestinal villus. go-plus.json villus epithelium|villous epithelium|intestinal villus epithelium http://purl.obolibrary.org/obo/UBERON_0013636 UBERON:0013637 biolink:AnatomicalEntity prostate gland lateral lobe The prostate gland lobe that is located on the lateral side of the organ. go-plus.json lateral lobe of prostate gland|lateral prostate|lateral ventral lobe of prostate gland|lateral lobe of prostate http://purl.obolibrary.org/obo/UBERON_0013637 CHEBI:75614 biolink:ChemicalSubstance 1-linoleoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75614 chebi_ph7_3 CHEBI:75611 biolink:ChemicalSubstance 1-arachidonoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75611 chebi_ph7_3 CHEBI:75612 biolink:ChemicalSubstance 1-arachidonoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75612 chebi_ph7_3 CHEBI:26649 biolink:ChemicalSubstance serine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_26649 CHEBI:26642 biolink:ChemicalSubstance selenous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26642 CHEBI:75617 biolink:ChemicalSubstance N(3')-acetylgentamycin C(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75617 chebi_ph7_3 CHEBI:26643 biolink:ChemicalSubstance aldehydic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26643 CHEBI:75615 biolink:ChemicalSubstance (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_75615 CHEBI:26645 biolink:ChemicalSubstance semiochemical go-plus.json http://purl.obolibrary.org/obo/CHEBI_26645 CHEBI:75616 biolink:ChemicalSubstance gentamicin C(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75616 chebi_ph7_3 UBERON:0013631 biolink:AnatomicalEntity sesamoid element Ossicle that develops within bands of dense, regular connective tissue (e.g., tendons and ligaments). Sesamoids are generally located proximate to a bony prominence, over which the dense regular connective tissue wraps, and/or a joint or articulation. go-plus.json sesamoid http://purl.obolibrary.org/obo/UBERON_0013631 UBERON:0013632 biolink:AnatomicalEntity sesamoid cartilage A sesamoid element that is composed primarily of cartilage tissue. go-plus.json cartilago sesamoidea|sesamoid cartilage of cricopharyngeal ligament http://purl.obolibrary.org/obo/UBERON_0013632 CHEBI:26640 biolink:ChemicalSubstance selenomethionines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26640 UBERON:0013630 biolink:AnatomicalEntity short bone Short bones are designated as those bones that are as wide as they are long. Their primary function is to provide support and stability with little to no movement. They are one of five types of bones: long, short, flat, irregular and sesamoid. Examples of these bones include the tarsals in the foot and the carpals in the hand. go-plus.json http://purl.obolibrary.org/obo/UBERON_0013630 CHEBI:75610 biolink:ChemicalSubstance 1-alpha-linolenoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75610 chebi_ph7_3 CHEBI:75624 biolink:ChemicalSubstance palmitoleyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75624 chebi_ph7_3 NCBITaxon:10088 biolink:OrganismalEntity Mus go-plus.json Mus|mouse|mice http://purl.obolibrary.org/obo/NCBITaxon_10088 CHEBI:75625 biolink:ChemicalSubstance stearyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75625 chebi_ph7_3 CHEBI:26658 biolink:ChemicalSubstance sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26658 CHEBI:75622 biolink:ChemicalSubstance palmityl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75622 chebi_ph7_3 CHEBI:75623 biolink:ChemicalSubstance palmitoleyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75623 chebi_ph7_3 CHEBI:75628 biolink:ChemicalSubstance arachidyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75628 chebi_ph7_3 CHEBI:75629 biolink:ChemicalSubstance palmityl palmitoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75629 chebi_ph7_3 CHEBI:75626 biolink:ChemicalSubstance oleyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75626 chebi_ph7_3 CHEBI:75627 biolink:ChemicalSubstance icosan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75627 chebi_ph7_3 CHEBI:26650 biolink:ChemicalSubstance serine family amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26650 CHEBI:75620 biolink:ChemicalSubstance decyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75620 chebi_ph7_3 CHEBI:75635 biolink:ChemicalSubstance mesaconyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75635 chebi_ph7_3 CHEBI:75636 biolink:ChemicalSubstance 3-methylfumaryl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75636 chebi_ph7_3 CHEBI:75634 biolink:ChemicalSubstance L-erythro-3-methylmalyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75634 chebi_ph7_3 CHEBI:75637 biolink:ChemicalSubstance (3R)-citramalyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75637 chebi_ph7_3 UBERON:0013697 biolink:AnatomicalEntity exocrine pancreas epithelium Epithelium lining the exocrine pancreas. go-plus.json epithelium of exocrine pancreas|exocrine pancreas epithelial cell http://purl.obolibrary.org/obo/UBERON_0013697 UBERON:0013699 biolink:AnatomicalEntity strand of axillary hair A strand of hair that is part of a axilla. go-plus.json axillary hair|hair of axilla|axilla hair http://purl.obolibrary.org/obo/UBERON_0013699 UBERON:0013694 biolink:AnatomicalEntity brain endothelium Vascular endothelium found in blood vessels of the blood-brain-barrier. go-plus.json cerebromicrovascular endothelium http://purl.obolibrary.org/obo/UBERON_0013694 UBERON:0013695 biolink:AnatomicalEntity colon endothelium Vascular endothelium found in colon blood vessels. go-plus.json colorectal endothelium|colonic endothelium|colonic endothelial cell|colorectal endothelial cell|colon endothelial cell|colon endothelial cells http://purl.obolibrary.org/obo/UBERON_0013695 CHEBI:26628 biolink:ChemicalSubstance selenium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_26628 CHEBI:75631 biolink:ChemicalSubstance palmityl stearate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75631 chebi_ph7_3 CHEBI:26629 biolink:ChemicalSubstance selenoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26629 CHEBI:75646 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75646 CHEBI:75645 biolink:ChemicalSubstance 1-acyl-2-palmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75645 CHEBI:26632 biolink:ChemicalSubstance selenocysteines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26632 CHEBI:75649 biolink:ChemicalSubstance 5-(2-methoxy-2-oxoethyl)uridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_75649 CHEBI:26634 biolink:ChemicalSubstance selenodiglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_26634 UBERON:0013686 biolink:AnatomicalEntity anatomical conduit space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. go-plus.json foramen space http://purl.obolibrary.org/obo/UBERON_0013686 CHEBI:26630 biolink:ChemicalSubstance selenocystathionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26630 CHEBI:61001 biolink:ChemicalSubstance 2-O-(6-phosphono-alpha-D-mannosyl)-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61001 UBERON:0013683 biolink:AnatomicalEntity left dorsal thalamus A dorsal thalamus that is in_the_left_side_of a diencephalon. go-plus.json left thalamus http://purl.obolibrary.org/obo/UBERON_0013683 UBERON:0013684 biolink:AnatomicalEntity right dorsal thalamus A dorsal thalamus that is in_the_right_side_of a diencephalon. go-plus.json right thalamus http://purl.obolibrary.org/obo/UBERON_0013684 UBERON:0013685 biolink:AnatomicalEntity foramen of skull Anatomical space that is an opening in a bone of the skull. go-plus.json cranial foramen|cranial conduit|foramina of the skull|foramen of skull http://purl.obolibrary.org/obo/UBERON_0013685 CHEBI:61006 biolink:ChemicalSubstance mannosyl diphosphorylinositol ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61006 CHEBI:61007 biolink:ChemicalSubstance amino fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61007 CHEBI:61008 biolink:ChemicalSubstance nitrogen-containing fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61008 CHEBI:75657 biolink:ChemicalSubstance 5-(carboxymethyl)uridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75657 CHEBI:75658 biolink:ChemicalSubstance 5-(carboxymethyl)uridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_75658 CHEBI:26604 biolink:ChemicalSubstance santonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26604 CHEBI:26605 biolink:ChemicalSubstance saponin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26605 CHEBI:75659 biolink:ChemicalSubstance O-acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75659 chebi_ph7_3 CHEBI:26600 biolink:ChemicalSubstance salutaridinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_26600 CHEBI:61011 biolink:ChemicalSubstance all-trans-decaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61011 CHEBI:61016 biolink:ChemicalSubstance angiotensin receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_61016 CHEBI:61015 biolink:ChemicalSubstance nephrotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61015 GO:0061700 biolink:CellularComponent GATOR2 complex A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins. go-plus.json SEACAT complex http://purl.obolibrary.org/obo/GO_0061700 GO:0061701 biolink:CellularComponent bacterial outer membrane vesicle A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0061701 GO:0061702 biolink:CellularComponent inflammasome complex A cytosolic protein complex that is capable of activating caspase-1. go-plus.json http://purl.obolibrary.org/obo/GO_0061702 GO:0061703 biolink:CellularComponent pyroptosome complex A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis. go-plus.json ASC pyroptosome http://purl.obolibrary.org/obo/GO_0061703 GO:0061704 biolink:BiologicalProcess glycolytic process from sucrose The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0061704 CHEBI:75650 biolink:ChemicalSubstance 5-(2-methoxy-2-oxoethyl)uridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75650 GO:0061705 biolink:BiologicalProcess sucrose catabolic process to fructose-6-phosphate through glucose and fructose The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates. MetaCyc:PWY-621 go-plus.json http://purl.obolibrary.org/obo/GO_0061705 GO:0061706 biolink:BiologicalProcess glycolytic process from sucrose through glucose and fructose The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. MetaCyc:PWY-1042 go-plus.json http://purl.obolibrary.org/obo/GO_0061706 GO:0061707 biolink:BiologicalProcess extracellular exosome macropinocytosis The single-organism macropinocytosis process that results in the uptake of an extracellular exosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061707 CHEBI:26606 biolink:ChemicalSubstance sapogenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26606 GO:0061708 biolink:MolecularActivity tRNA-5-taurinomethyluridine 2-sulfurtransferase Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+. Reactome:R-HSA-6787447|RHEA:47040|MetaCyc:RXN-16821 go-plus.json http://purl.obolibrary.org/obo/GO_0061708 CHEBI:26607 biolink:ChemicalSubstance saturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26607 GO:0061709 biolink:BiologicalProcess reticulophagy The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions. go-plus.json endoplasmic reticulum autophagy|ER-phagy|ER autophagy|autophagy of the ER|endoplasmic reticulum degradation|ER degradation|autophagy of the endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0061709 NCBITaxon:58022 biolink:OrganismalEntity Gnetophyta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_58022 CHEBI:26613 biolink:ChemicalSubstance scyllo-inositol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26613 NCBITaxon:58023 biolink:OrganismalEntity Tracheophyta go-plus.json vascular plants|vascular plants http://purl.obolibrary.org/obo/NCBITaxon_58023 NCBITaxon:58024 biolink:OrganismalEntity Spermatophyta go-plus.json seed plants|seed plants http://purl.obolibrary.org/obo/NCBITaxon_58024 CHEBI:26616 biolink:ChemicalSubstance seco-androstane go-plus.json http://purl.obolibrary.org/obo/CHEBI_26616 CHEBI:61027 biolink:ChemicalSubstance (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61027 CHEBI:75665 biolink:ChemicalSubstance (2S,3R)-capreomycidine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75665 chebi_ph7_3 GO:0071087 biolink:CellularComponent alpha11-beta1 integrin-collagen type I complex A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen. go-plus.json ITGA11-ITGB1-COL1A1 complex http://purl.obolibrary.org/obo/GO_0071087 GO:0071088 biolink:CellularComponent alpha5-beta1 integrin-tissue transglutaminase complex A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase. go-plus.json ITGA5-ITGB1-TGM2 complex http://purl.obolibrary.org/obo/GO_0071088 GO:0071085 biolink:CellularComponent alphaIIb-beta3 integrin-CD9 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9. go-plus.json ITGA2b-ITGB3-CD9 complex http://purl.obolibrary.org/obo/GO_0071085 GO:0071086 biolink:CellularComponent alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib. go-plus.json ITGA2b-ITGB3-CD9-GP1b-CD47 complex http://purl.obolibrary.org/obo/GO_0071086 GO:0071083 biolink:CellularComponent alphaV-beta3 integrin-CD47-FCER2 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2). go-plus.json ITGAV-ITGB3-CD447-FCER2 complex http://purl.obolibrary.org/obo/GO_0071083 GO:0071084 biolink:CellularComponent alpha2-beta1 integrin-CD47 complex A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47. go-plus.json ITGA2-ITGB1-CD47 complex http://purl.obolibrary.org/obo/GO_0071084 GO:0071081 biolink:CellularComponent alpha3-beta1 integrin-CD63 complex A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63. go-plus.json ITGA3-ITGB1-CD63 complex http://purl.obolibrary.org/obo/GO_0071081 GO:0071082 biolink:CellularComponent alpha9-beta1 integrin-tenascin complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin. go-plus.json ITGA9-ITGB1-TNC complex http://purl.obolibrary.org/obo/GO_0071082 GO:0071080 biolink:CellularComponent alpha3-beta1 integrin-basigin complex A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin. go-plus.json ITGA3-ITGB1-BSG complex http://purl.obolibrary.org/obo/GO_0071080 GO:1901288 biolink:BiologicalProcess iron-sulfur-molybdenum cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor. go-plus.json iron-sulfur-molybdenum cofactor formation|FeMo-co formation|iron-molybdenum cofactor biosynthetic process|iron-molybdenum cofactor biosynthesis|iron-molybdenum cofactor anabolism|iron-molybdenum cofactor synthesis|iron-molybdenum cofactor formation|FeMo-co biosynthetic process|FeMo-co biosynthesis|iron-sulfur-molybdenum cofactor anabolism|iron-sulfur-molybdenum cofactor biosynthesis|FeMo-co anabolism|iron-sulfur-molybdenum cofactor synthesis|FeMo-co synthesis http://purl.obolibrary.org/obo/GO_1901288 GO:1901289 biolink:BiologicalProcess succinyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of succinyl-CoA. go-plus.json succinyl-CoA degradation|succinyl-CoA breakdown|succinyl-CoA catabolism http://purl.obolibrary.org/obo/GO_1901289 GO:1901286 biolink:BiologicalProcess iron-sulfur-molybdenum cofactor metabolic process The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor. go-plus.json iron-molybdenum cofactor metabolic process|iron-molybdenum cofactor metabolism|FeMo-co metabolic process|FeMo-co metabolism|iron-sulfur-molybdenum cofactor metabolism http://purl.obolibrary.org/obo/GO_1901286 GO:1901287 biolink:BiologicalProcess iron-sulfur-molybdenum cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor. go-plus.json iron-sulfur-molybdenum cofactor degradation|FeMo-co degradation|iron-molybdenum degradation|iron-sulfur-molybdenum cofactor breakdown|FeMo-co breakdown|iron-molybdenum catabolism|iron-molybdenum breakdown|FeMo-co catabolism|FeMo-co catabolic process|iron-molybdenum catabolic process|iron-sulfur-molybdenum cofactor catabolism http://purl.obolibrary.org/obo/GO_1901287 GO:1901295 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. go-plus.json regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment http://purl.obolibrary.org/obo/GO_1901295 GO:1901296 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. go-plus.json downregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|downregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment http://purl.obolibrary.org/obo/GO_1901296 GO:1901293 biolink:BiologicalProcess nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. go-plus.json nucleoside phosphate anabolism|nucleoside phosphate synthesis|nucleoside phosphate formation|nucleoside phosphate biosynthesis http://purl.obolibrary.org/obo/GO_1901293 GO:1901294 biolink:BiologicalProcess obsolete negative regulation of SREBP signaling pathway by negative regulation of DNA binding OBSOLETE. Negative regulation of DNA binding that results in negative regulation of a SREBP signaling pathway. go-plus.json negative regulation of SREBP-mediated signalling pathway by down regulation of DNA binding|negative regulation of SREBP signaling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signaling pathway by downregulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by negative regulation of DNA binding|negative regulation of SREBP signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by inhibition of DNA binding|inhibition of SREBP-dependent transcription by blocking DNA binding|negative regulation of SREBP-mediated signalling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by negative regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by inhibition of DNA binding|negative regulation of SREBP signaling pathway by downregulation of DNA binding|negative regulation of SREBP signaling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by downregulation of DNA binding http://purl.obolibrary.org/obo/GO_1901294 GO:1901291 biolink:BiologicalProcess negative regulation of double-strand break repair via single-strand annealing Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing. go-plus.json downregulation of double-strand break repair via single-strand annealing|down regulation of double-strand break repair via single-strand annealing|inhibition of double-strand break repair via single-strand annealing|down-regulation of double-strand break repair via single-strand annealing http://purl.obolibrary.org/obo/GO_1901291 GO:1901292 biolink:BiologicalProcess nucleoside phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate. go-plus.json nucleoside phosphate degradation|nucleoside phosphate breakdown|nucleoside phosphate catabolism http://purl.obolibrary.org/obo/GO_1901292 GO:1901290 biolink:BiologicalProcess succinyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of succinyl-CoA. go-plus.json succinyl-CoA formation|succinyl-CoA biosynthesis|succinyl-CoA anabolism|succinyl-CoA synthesis http://purl.obolibrary.org/obo/GO_1901290 CHEBI:36063 biolink:ChemicalSubstance oxytocic go-plus.json http://purl.obolibrary.org/obo/CHEBI_36063 CHEBI:36064 biolink:ChemicalSubstance taxane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36064 chebi_ph7_3 CHEBI:36061 biolink:ChemicalSubstance octa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36061 CHEBI:36062 biolink:ChemicalSubstance 3,4-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36062 GO:0071089 biolink:CellularComponent alphaV-beta3 integrin-tissue transglutaminase complex A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase. go-plus.json ITGAV-ITGB3-TGM2 complex http://purl.obolibrary.org/obo/GO_0071089 CHEBI:36066 biolink:ChemicalSubstance prostaglandins Falpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_36066 chebi_ph7_3 GO:0071076 biolink:BiologicalProcess RNA 3' uridylation The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0071076 GO:0071077 biolink:MolecularActivity adenosine 3',5'-bisphosphate transmembrane transporter activity Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other. go-plus.json adenosine 3',5'-diphosphate transporter activity|adenosine 3'-phosphate-5'-phosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0071077 GO:0071074 biolink:MolecularActivity eukaryotic initiation factor eIF2 binding Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation. go-plus.json http://purl.obolibrary.org/obo/GO_0071074 CHEBI:145951 biolink:ChemicalSubstance 4-hydroxymethylsteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145951 chebi_ph7_3 GO:0071075 biolink:CellularComponent CUGBP1-eIF2 complex A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation. go-plus.json http://purl.obolibrary.org/obo/GO_0071075 GO:0071072 biolink:BiologicalProcess negative regulation of phospholipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. go-plus.json negative regulation of phospholipid biosynthesis|inhibition of phospholipid biosynthetic process|negative regulation of phospholipid anabolism|down regulation of phospholipid biosynthetic process|negative regulation of phospholipid synthesis|downregulation of phospholipid biosynthetic process|negative regulation of phospholipid formation|down-regulation of phospholipid biosynthetic process http://purl.obolibrary.org/obo/GO_0071072 CHEBI:145952 biolink:ChemicalSubstance 4-formyl steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145952 chebi_ph7_3 GO:0071073 biolink:BiologicalProcess positive regulation of phospholipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. go-plus.json up-regulation of phospholipid biosynthetic process|upregulation of phospholipid biosynthetic process|positive regulation of phospholipid anabolism|up regulation of phospholipid biosynthetic process|positive regulation of phospholipid synthesis|activation of phospholipid biosynthetic process|positive regulation of phospholipid biosynthesis|positive regulation of phospholipid formation|stimulation of phospholipid biosynthetic process http://purl.obolibrary.org/obo/GO_0071073 GO:0071070 biolink:CellularComponent alpha4-beta1 integrin-thrombospondin-2 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2. go-plus.json ITGA4-ITGB1-THBS2 complex http://purl.obolibrary.org/obo/GO_0071070 CHEBI:145954 biolink:ChemicalSubstance 4alpha-formyl steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145954 chebi_ph7_3 GO:0071071 biolink:BiologicalProcess regulation of phospholipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. go-plus.json regulation of phospholipid synthesis|regulation of phospholipid formation|regulation of phospholipid biosynthesis|regulation of phospholipid anabolism http://purl.obolibrary.org/obo/GO_0071071 CHEBI:36080 biolink:ChemicalSubstance protein go-plus.json http://purl.obolibrary.org/obo/CHEBI_36080 GO:1901299 biolink:BiologicalProcess negative regulation of hydrogen peroxide-mediated programmed cell death Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. go-plus.json down regulation of hydrogen peroxide-mediated programmed cell death|inhibition of hydrogen peroxide-mediated programmed cell death|down-regulation of hydrogen peroxide-mediated programmed cell death|downregulation of hydrogen peroxide-mediated programmed cell death http://purl.obolibrary.org/obo/GO_1901299 GO:1901297 biolink:BiologicalProcess positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. go-plus.json positive regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment http://purl.obolibrary.org/obo/GO_1901297 GO:1901298 biolink:BiologicalProcess regulation of hydrogen peroxide-mediated programmed cell death Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. go-plus.json http://purl.obolibrary.org/obo/GO_1901298 CHEBI:36078 biolink:ChemicalSubstance cholanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36078 GO:0071078 biolink:CellularComponent fibronectin-tissue transglutaminase complex A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion. go-plus.json FN-TGM2 complex http://purl.obolibrary.org/obo/GO_0071078 GO:0071079 biolink:CellularComponent alpha2-beta1 integrin-chondroadherin complex A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin. go-plus.json ITGA2-ITGB1-CHAD complex http://purl.obolibrary.org/obo/GO_0071079 CHEBI:145942 biolink:ChemicalSubstance 4alpha-formyl-5alpha-cholest-7-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_145942 chebi_ph7_3 CHEBI:145943 biolink:ChemicalSubstance 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145943 chebi_ph7_3 CHEBI:51688 biolink:ChemicalSubstance enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51688 chebi_ph7_3 CHEBI:51689 biolink:ChemicalSubstance enone go-plus.json http://purl.obolibrary.org/obo/CHEBI_51689 chebi_ph7_3 CHEBI:36047 biolink:ChemicalSubstance antibacterial drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_36047 CHEBI:145945 biolink:ChemicalSubstance 4beta-hydroxymethyl steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145945 chebi_ph7_3 CHEBI:36042 biolink:ChemicalSubstance icosa-5,9,11,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36042 CHEBI:145946 biolink:ChemicalSubstance N-acetyl-D-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_145946 chebi_ph7_3 CHEBI:51683 biolink:ChemicalSubstance methoxybenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_51683 CHEBI:145947 biolink:ChemicalSubstance antiatherosclerotic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_145947 CHEBI:36040 biolink:ChemicalSubstance icosa-6,8,11,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36040 CHEBI:36045 biolink:ChemicalSubstance icosa-6,8,10,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36045 CHEBI:36046 biolink:ChemicalSubstance icosatetraenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36046 CHEBI:36043 biolink:ChemicalSubstance antimicrobial drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_36043 CHEBI:36044 biolink:ChemicalSubstance antiviral drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_36044 CHEBI:51681 biolink:ChemicalSubstance dimethoxybenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_51681 GO:0071098 biolink:CellularComponent alpha6-beta4 integrin-Fyn complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn. go-plus.json ITGA6-ITGB4-FYN complex http://purl.obolibrary.org/obo/GO_0071098 GO:0071099 biolink:CellularComponent alphaV-beta6 integrin-TGFbeta-3 complex A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3). go-plus.json ITGAV-ITGB6-TFGB3 complex http://purl.obolibrary.org/obo/GO_0071099 GO:0071096 biolink:CellularComponent alphaV-beta3 integrin-gelsolin complex A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin. go-plus.json ITGAV-ITGB3-Gsn complex http://purl.obolibrary.org/obo/GO_0071096 GO:0071097 biolink:CellularComponent alphaV-beta3 integrin-paxillin-Pyk2 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2. go-plus.json ITGAV-ITGB3-PXN-PTK2b complex http://purl.obolibrary.org/obo/GO_0071097 GO:0071094 biolink:CellularComponent alpha6-beta4 integrin-CD9 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9. go-plus.json ITGA6-ITGB4-CD9 complex http://purl.obolibrary.org/obo/GO_0071094 GO:0071095 biolink:CellularComponent alpha3-beta1 integrin-thrombospondin complex A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin. go-plus.json ITGA3-ITGB1-THBS1 complex http://purl.obolibrary.org/obo/GO_0071095 GO:0071092 biolink:CellularComponent alpha3-beta1 integrin-tissue transglutaminase complex A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase. go-plus.json ITGA3-ITGB1-TGM2 complex http://purl.obolibrary.org/obo/GO_0071092 CHEBI:145932 biolink:ChemicalSubstance (S)-2-methylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_145932 chebi_ph7_3 GO:0071093 biolink:CellularComponent alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase. go-plus.json ITGA5-ITGB1-FN1-TGM2 complex http://purl.obolibrary.org/obo/GO_0071093 GO:0071090 biolink:CellularComponent alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase. go-plus.json ITGA2b-ITGB3-FN1-TGM2 complex http://purl.obolibrary.org/obo/GO_0071090 GO:0071091 biolink:CellularComponent alpha1-beta1 integrin-tissue transglutaminase complex A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase. go-plus.json ITGA1-ITGB1-TGM2 complex http://purl.obolibrary.org/obo/GO_0071091 CHEBI:36059 biolink:ChemicalSubstance hydroxy monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36059 CHEBI:36056 biolink:ChemicalSubstance furancarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36056 CHEBI:36054 biolink:ChemicalSubstance benzoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_36054 CHEBI:36055 biolink:ChemicalSubstance furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36055 CHEBI:36027 biolink:ChemicalSubstance stilbenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_36027 CHEBI:36025 biolink:ChemicalSubstance octadeca-9,11-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36025 CHEBI:36029 biolink:ChemicalSubstance butenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36029 UBERON:0013605 biolink:AnatomicalEntity layer of lateral geniculate body go-plus.json http://purl.obolibrary.org/obo/UBERON_0013605 CHEBI:36023 biolink:ChemicalSubstance vaccenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36023 CHEBI:36024 biolink:ChemicalSubstance trideca-2,6-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36024 CHEBI:36021 biolink:ChemicalSubstance octadec-9-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36021 CHEBI:36022 biolink:ChemicalSubstance octadec-6-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36022 CHEBI:36038 biolink:ChemicalSubstance icosa-7,9,11,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36038 CHEBI:36039 biolink:ChemicalSubstance icosa-5,8,10,14-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36039 CHEBI:36036 biolink:ChemicalSubstance fatty acid 20:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_36036 CHEBI:36037 biolink:ChemicalSubstance (5Z,9E,14Z)-icosa-5,9,14-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36037 CHEBI:36030 biolink:ChemicalSubstance pentenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36030 CHEBI:106304 biolink:ChemicalSubstance sphingomyelin d18:1/16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_106304 chebi_ph7_3 CHEBI:36031 biolink:ChemicalSubstance docosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36031 CHEBI:51652 biolink:ChemicalSubstance dithianes go-plus.json http://purl.obolibrary.org/obo/CHEBI_51652 CHEBI:36035 biolink:ChemicalSubstance icosa-5,8,11,13-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36035 CHEBI:36032 biolink:ChemicalSubstance tetracosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36032 CHEBI:36033 biolink:ChemicalSubstance icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36033 CHEBI:12040 biolink:ChemicalSubstance 4-oxohex-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12040 chebi_ph7_3 CHEBI:26689 biolink:ChemicalSubstance singlet dioxygen go-plus.json http://purl.obolibrary.org/obo/CHEBI_26689 chebi_ph7_3 CHEBI:36005 biolink:ChemicalSubstance docosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36005 CHEBI:36006 biolink:ChemicalSubstance icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36006 CHEBI:36003 biolink:ChemicalSubstance decenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36003 CHEBI:36004 biolink:ChemicalSubstance tetradecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36004 CHEBI:36009 biolink:ChemicalSubstance omega-6 fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36009 CHEBI:36007 biolink:ChemicalSubstance trans-stilbene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36007 chebi_ph7_3 CHEBI:145902 biolink:ChemicalSubstance 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145902 chebi_ph7_3 CHEBI:12071 biolink:ChemicalSubstance 5,10-methylenetetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_12071 chebi_ph7_3 CHEBI:36016 biolink:ChemicalSubstance chloroethanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_36016 CHEBI:36014 biolink:ChemicalSubstance chloromethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36014 chebi_ph7_3 CHEBI:12060 biolink:ChemicalSubstance 5'-deoxy-5'-fluoroadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_12060 chebi_ph7_3 CHEBI:36011 biolink:ChemicalSubstance pinosylvin go-plus.json http://purl.obolibrary.org/obo/CHEBI_36011 chebi_ph7_3 GO:0046043 biolink:BiologicalProcess TDP metabolic process The chemical reactions and pathways involving TDP, ribosylthymine diphosphate. go-plus.json TDP metabolism http://purl.obolibrary.org/obo/GO_0046043 GO:0071000 biolink:BiologicalProcess response to magnetism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus. go-plus.json response to magnetic stimulus http://purl.obolibrary.org/obo/GO_0071000 GO:0046044 biolink:BiologicalProcess TMP metabolic process The chemical reactions and pathways involving TMP, ribosylthymine monophosphate. go-plus.json TMP metabolism http://purl.obolibrary.org/obo/GO_0046044 GO:0046041 biolink:BiologicalProcess ITP metabolic process The chemical reactions and pathways involving ITP, inosine triphosphate. go-plus.json ITP metabolism http://purl.obolibrary.org/obo/GO_0046041 NCBITaxon:324602 biolink:OrganismalEntity Chloroflexus aurantiacus J-10-fl go-plus.json Chloroflexus aurantiacus str. J-10-fl|Chloroflexus aurantiacus DSM 635|Chloroflexus aurantiacus strain J-10-fl|Chloroflexus aurantiacus ATCC 29366 http://purl.obolibrary.org/obo/NCBITaxon_324602 GO:0046042 biolink:BiologicalProcess ITP biosynthetic process The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate. go-plus.json ITP biosynthesis|ITP anabolism|ITP synthesis|ITP formation http://purl.obolibrary.org/obo/GO_0046042 GO:1901208 biolink:BiologicalProcess negative regulation of heart looping Any process that stops, prevents or reduces the frequency, rate or extent of heart looping. go-plus.json down regulation of heart looping|inhibition of cardiac looping|downregulation of heart looping|down regulation of cardiac looping|down-regulation of heart looping|downregulation of cardiac looping|inhibition of heart looping|down-regulation of cardiac looping|negative regulation of cardiac looping http://purl.obolibrary.org/obo/GO_1901208 GO:1901209 biolink:BiologicalProcess positive regulation of heart looping Any process that activates or increases the frequency, rate or extent of heart looping. go-plus.json activation of cardiac looping|upregulation of heart looping|up-regulation of cardiac looping|up regulation of heart looping|upregulation of cardiac looping|activation of heart looping|up regulation of cardiac looping|up-regulation of heart looping|positive regulation of cardiac looping http://purl.obolibrary.org/obo/GO_1901209 GO:0046040 biolink:BiologicalProcess IMP metabolic process The chemical reactions and pathways involving IMP, inosine monophosphate. go-plus.json IMP metabolism http://purl.obolibrary.org/obo/GO_0046040 GO:1901206 biolink:BiologicalProcess obsolete positive regulation of adrenergic receptor signaling pathway involved in heart process OBSOLETE. Any process that activates or increases the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. go-plus.json up-regulation of beta-adrenergic receptor signalling pathway involved in heart process|positive regulation of adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signaling pathway involved in heart process|upregulation of beta-adrenergic receptor signalling pathway involved in heart process|upregulation of adrenergic receptor signalling pathway involved in heart process|upregulation of adrenergic receptor signaling pathway involved in heart process|up regulation of beta-adrenergic receptor signalling pathway involved in heart process|positive regulation of beta-adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signaling pathway involved in heart process|activation of beta-adrenergic receptor signalling pathway involved in heart process|activation of adrenergic receptor signaling pathway involved in heart process|activation of adrenergic receptor signalling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1901206 GO:1901207 biolink:BiologicalProcess regulation of heart looping Any process that modulates the frequency, rate or extent of heart looping. go-plus.json regulation of cardiac looping http://purl.obolibrary.org/obo/GO_1901207 GO:1901204 biolink:BiologicalProcess obsolete regulation of adrenergic receptor signaling pathway involved in heart process OBSOLETE. Any process that modulates the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. go-plus.json regulation of adrenergic receptor signalling pathway involved in heart process|regulation of beta-adrenergic receptor signalling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1901204 GO:1901205 biolink:BiologicalProcess obsolete negative regulation of adrenergic receptor signaling pathway involved in heart process OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. go-plus.json inhibition of beta-adrenergic receptor signalling pathway involved in heart process|inhibition of adrenergic receptor signaling pathway involved in heart process|downregulation of adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signalling pathway involved in heart process|down regulation of beta-adrenergic receptor signalling pathway involved in heart process|downregulation of beta-adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signaling pathway involved in heart process|inhibition of adrenergic receptor signalling pathway involved in heart process|downregulation of adrenergic receptor signaling pathway involved in heart process|down-regulation of beta-adrenergic receptor signalling pathway involved in heart process|negative regulation of beta-adrenergic receptor signalling pathway involved in heart process|down-regulation of adrenergic receptor signaling pathway involved in heart process|down-regulation of adrenergic receptor signalling pathway involved in heart process|negative regulation of adrenergic receptor signalling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1901205 GO:1901202 biolink:BiologicalProcess negative regulation of extracellular matrix assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. go-plus.json down regulation of extracellular matrix assembly|downregulation of extracellular matrix assembly|down-regulation of extracellular matrix assembly|inhibition of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1901202 GO:0046049 biolink:BiologicalProcess UMP metabolic process The chemical reactions and pathways involving UMP, uridine monophosphate. go-plus.json UMP metabolism http://purl.obolibrary.org/obo/GO_0046049 GO:1901203 biolink:BiologicalProcess positive regulation of extracellular matrix assembly Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. go-plus.json upregulation of extracellular matrix assembly|up regulation of extracellular matrix assembly|activation of extracellular matrix assembly|up-regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1901203 GO:0046047 biolink:BiologicalProcess TTP catabolic process The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate. go-plus.json TTP catabolism|TTP degradation|TTP breakdown|TTP hydrolysis http://purl.obolibrary.org/obo/GO_0046047 GO:0061680 biolink:BiologicalProcess Entner-Doudoroff pathway through gluconate to D-glyceraldehyde The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde. MetaCyc:ENTNER-DOUDOROFF-PWY-II go-plus.json http://purl.obolibrary.org/obo/GO_0061680 GO:1901200 biolink:BiologicalProcess negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress. go-plus.json negative regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|negative regulation of calcium ion transport into cytosol involved in cellular salinity response http://purl.obolibrary.org/obo/GO_1901200 GO:0061681 biolink:BiologicalProcess Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate. MetaCyc:ENTNER-DOUDOROFF-PWY-III go-plus.json http://purl.obolibrary.org/obo/GO_0061681 GO:1901201 biolink:BiologicalProcess regulation of extracellular matrix assembly Any process that modulates the frequency, rate or extent of extracellular matrix assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1901201 GO:0046048 biolink:BiologicalProcess UDP metabolic process The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate. go-plus.json UDP metabolism http://purl.obolibrary.org/obo/GO_0046048 GO:0046045 biolink:BiologicalProcess TMP catabolic process The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate. go-plus.json TMP degradation|TMP breakdown|TMP catabolism http://purl.obolibrary.org/obo/GO_0046045 GO:0061682 biolink:BiologicalProcess seminal vesicle morphogenesis The process in which the anatomical structures of a seminal vesicle are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061682 GO:0061683 biolink:BiologicalProcess branching involved in seminal vesicle morphogenesis The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem. go-plus.json seminal vesicle branching morphogenesis|seminal vesicle branching|seminal gland branching morphogenesis|gonecyst branching morphogenesis http://purl.obolibrary.org/obo/GO_0061683 GO:0046046 biolink:BiologicalProcess TTP metabolic process The chemical reactions and pathways involving TTP, ribosylthymine triphosphate. go-plus.json TTP metabolism http://purl.obolibrary.org/obo/GO_0046046 GO:0061684 biolink:BiologicalProcess chaperone-mediated autophagy The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded. Wikipedia:Chaperone-mediated_autophagy go-plus.json CMA|CASA|chaperone-assisted selective autophagy http://purl.obolibrary.org/obo/GO_0061684 GO:0061685 biolink:MolecularActivity diphthine methylesterase activity Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol. RHEA:42656|EC:3.1.1.97 go-plus.json http://purl.obolibrary.org/obo/GO_0061685 GO:0061686 biolink:MolecularActivity hercynylcysteine sulfoxide synthase activity Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 <=> hercynylcysteine sulfoxide + H2O. EC:1.14.99.51|RHEA:42704 go-plus.json hercynylcysteine S-oxide synthase|hercynylcysteine sulfoxide synthase http://purl.obolibrary.org/obo/GO_0061686 GO:0061687 biolink:BiologicalProcess detoxification of inorganic compound Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0061687 GO:0061688 biolink:BiologicalProcess glycolytic process via Entner-Doudoroff Pathway A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes. go-plus.json gluconate pathway http://purl.obolibrary.org/obo/GO_0061688 GO:0061689 biolink:CellularComponent tricellular tight junction An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0061689 GO:0071009 biolink:CellularComponent U4atac/U6atac x U5 tri-snRNP complex A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs. go-plus.json U4atac/U6atac.U5 snRNP complex http://purl.obolibrary.org/obo/GO_0071009 GO:0071007 biolink:CellularComponent U2-type catalytic step 2 spliceosome A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs. go-plus.json GT-AG catalytic step 2 spliceosome|yeast U2-type spliceosomal complex A2-2|mammalian U2-type spliceosomal complex C1|major catalytic step 2 spliceosome|mammalian U2-type spliceosomal complex C http://purl.obolibrary.org/obo/GO_0071007 GO:0071008 biolink:CellularComponent U2-type post-mRNA release spliceosomal complex A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs. go-plus.json major post-mRNA release spliceosomal complex|GT-AG post-mRNA release spliceosomal complex|U2/U5/U6 tri-snRNP complex|mammalian U2-type spliceosomal complex I|U2/U5/U6 snRNP complex http://purl.obolibrary.org/obo/GO_0071008 GO:0071005 biolink:CellularComponent U2-type precatalytic spliceosome A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs. go-plus.json yeast U12-type spliceosomal complex A2-1|major precatalytic spliceosome|mammalian U2-type spliceosomal complex B1|GT-AG precatalytic spliceosome|mammalian U2-type spliceosomal complex B http://purl.obolibrary.org/obo/GO_0071005 GO:0071006 biolink:CellularComponent U2-type catalytic step 1 spliceosome A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs. go-plus.json GT-AG catalytic step 1 spliceosome|mammalian U2-type spliceosomal complex B*|U2-type activated spliceosome|mammalian U2-type spliceosomal complex B2|yeast U2-type spliceosomal complex A1|major catalytic step 1 spliceosome http://purl.obolibrary.org/obo/GO_0071006 GO:0071003 biolink:CellularComponent penta-snRNP complex A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins. go-plus.json penta-RNP complex http://purl.obolibrary.org/obo/GO_0071003 GO:0071004 biolink:CellularComponent U2-type prespliceosome A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. go-plus.json major prespliceosome|GT-AG prespliceosome|yeast U2-type spliceosomal complex B|mammalian U2-type spliceosomal complex A http://purl.obolibrary.org/obo/GO_0071004 CHEBI:9003 biolink:ChemicalSubstance salicin 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_9003 GO:0071001 biolink:CellularComponent U4/U6 snRNP A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0071001 GO:0071002 biolink:CellularComponent U4atac/U6atac snRNP A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0071002 GO:0046054 biolink:BiologicalProcess dGMP metabolic process The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). go-plus.json dGMP metabolism http://purl.obolibrary.org/obo/GO_0046054 GO:0046055 biolink:BiologicalProcess dGMP catabolic process The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). go-plus.json dGMP degradation|dGMP catabolism|dGMP breakdown http://purl.obolibrary.org/obo/GO_0046055 GO:0046052 biolink:BiologicalProcess UTP catabolic process The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate. go-plus.json UTP degradation|UTP breakdown|UTP hydrolysis|UTP catabolism http://purl.obolibrary.org/obo/GO_0046052 GO:0046053 biolink:BiologicalProcess dAMP metabolic process The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). go-plus.json dAMP metabolism http://purl.obolibrary.org/obo/GO_0046053 GO:0046050 biolink:BiologicalProcess UMP catabolic process The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate. go-plus.json UMP degradation|UMP breakdown|UMP catabolism http://purl.obolibrary.org/obo/GO_0046050 GO:1901219 biolink:BiologicalProcess regulation of cardiac chamber morphogenesis Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. go-plus.json regulation of heart chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 GO:0046051 biolink:BiologicalProcess UTP metabolic process The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate. go-plus.json UTP metabolism http://purl.obolibrary.org/obo/GO_0046051 GO:1901217 biolink:BiologicalProcess regulation of holin activity Any process that modulates the frequency, rate or extent of holin activity. go-plus.json http://purl.obolibrary.org/obo/GO_1901217 GO:1901218 biolink:BiologicalProcess negative regulation of holin activity Any process that stops, prevents or reduces the frequency, rate or extent of holin activity. go-plus.json down-regulation of holin activity|downregulation of holin activity|down regulation of holin activity|antiholin activity|inhibition of holin activity|phage antiholin http://purl.obolibrary.org/obo/GO_1901218 GO:1901215 biolink:BiologicalProcess negative regulation of neuron death Any process that stops, prevents or reduces the frequency, rate or extent of neuron death. go-plus.json down regulation of neuronal cell death|negative regulation of neuron cell death|down-regulation of neuron death|down-regulation of neuron cell death|downregulation of neuronal cell death|inhibition of neuron cell death|downregulation of neuron death|negative regulation of neuronal cell death|down-regulation of neuronal cell death|down regulation of neuron death|inhibition of neuron death|inhibition of neuronal cell death|down regulation of neuron cell death|downregulation of neuron cell death http://purl.obolibrary.org/obo/GO_1901215 GO:1901216 biolink:BiologicalProcess positive regulation of neuron death Any process that activates or increases the frequency, rate or extent of neuron death. go-plus.json up regulation of neuronal cell death|up regulation of neuron death|activation of neuronal cell death|up-regulation of neuron cell death|positive regulation of neuronal cell death|upregulation of neuron cell death|upregulation of neuron death|up-regulation of neuronal cell death|up-regulation of neuron death|up regulation of neuron cell death|activation of neuron death|upregulation of neuronal cell death|positive regulation of neuron cell death|activation of neuron cell death http://purl.obolibrary.org/obo/GO_1901216 GO:1901213 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in heart development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the development of the heart over time. go-plus.json regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|regulation of global transcription from Pol II promoter involved in heart development|regulation of transcription from Pol II promoter involved in cardiac development|regulation of transcription from RNA polymerase II promoter, global involved in heart development|regulation of transcription from RNA polymerase II promoter involved in cardiac development|regulation of global transcription from Pol II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|regulation of global transcription from Pol II promoter involved in cardiac development|global transcription regulation from Pol II promoter involved in heart development|regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|regulation of transcription from Pol II promoter involved in heart development|regulation of transcription from Pol II promoter involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in dorsal vessel development http://purl.obolibrary.org/obo/GO_1901213 GO:1901214 biolink:BiologicalProcess regulation of neuron death Any process that modulates the frequency, rate or extent of neuron death. go-plus.json regulation of neuronal cell death|regulation of neuron cell death http://purl.obolibrary.org/obo/GO_1901214 GO:0046058 biolink:BiologicalProcess cAMP metabolic process The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json 3',5' cAMP metabolic process|3',5' cAMP metabolism|cyclic AMP metabolism|adenosine 3',5'-cyclophosphate metabolism|cAMP metabolism|cAMP generating peptide activity|3',5'-cAMP metabolic process|3',5'-cAMP metabolism|adenosine 3',5'-cyclophosphate metabolic process|cyclic AMP metabolic process http://purl.obolibrary.org/obo/GO_0046058 GO:1901211 biolink:BiologicalProcess negative regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. go-plus.json down regulation of heart chamber formation|downregulation of heart chamber formation|down regulation of cardiac chamber formation|negative regulation of heart chamber formation|down-regulation of heart chamber formation|downregulation of cardiac chamber formation|down-regulation of cardiac chamber formation|inhibition of heart chamber formation|inhibition of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901211 GO:1901212 biolink:BiologicalProcess positive regulation of cardiac chamber formation Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. go-plus.json up-regulation of cardiac chamber formation|up regulation of heart chamber formation|upregulation of cardiac chamber formation|positive regulation of heart chamber formation|activation of heart chamber formation|up regulation of cardiac chamber formation|activation of cardiac chamber formation|up-regulation of heart chamber formation|upregulation of heart chamber formation http://purl.obolibrary.org/obo/GO_1901212 GO:0046059 biolink:BiologicalProcess dAMP catabolic process The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). go-plus.json dAMP catabolism|dAMP degradation|dAMP breakdown http://purl.obolibrary.org/obo/GO_0046059 GO:0061670 biolink:BiologicalProcess evoked neurotransmitter secretion Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential. go-plus.json stimulus-dependant neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0061670 GO:0061671 biolink:CellularComponent Cbp3p-Cbp6 complex A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0061671 GO:0046056 biolink:BiologicalProcess dADP metabolic process The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate). go-plus.json dADP metabolism http://purl.obolibrary.org/obo/GO_0046056 GO:1901210 biolink:BiologicalProcess regulation of cardiac chamber formation Any process that modulates the frequency, rate or extent of cardiac chamber formation. go-plus.json regulation of heart chamber formation http://purl.obolibrary.org/obo/GO_1901210 GO:0061672 biolink:CellularComponent glutathione hydrolase complex Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly. go-plus.json glutamine amidotransferase II complex|gamma-glutamyltranspeptidase complex|glutathionase complex http://purl.obolibrary.org/obo/GO_0061672 GO:0046057 biolink:BiologicalProcess dADP catabolic process The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate). go-plus.json dADP degradation|dADP breakdown|dADP catabolism http://purl.obolibrary.org/obo/GO_0046057 GO:0061673 biolink:CellularComponent mitotic spindle astral microtubule Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061673 GO:0061674 biolink:BiologicalProcess gap filling involved in double-strand break repair via nonhomologous end joining Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining. go-plus.json http://purl.obolibrary.org/obo/GO_0061674 GO:0061675 biolink:MolecularActivity RBL family protein binding Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose. go-plus.json rhamnose-binding lectin family protein binding http://purl.obolibrary.org/obo/GO_0061675 GO:0061676 biolink:MolecularActivity importin-alpha family protein binding Binding to a member of the importin-alpha family. go-plus.json http://purl.obolibrary.org/obo/GO_0061676 GO:0061677 biolink:MolecularActivity 2-dehydro-3-deoxy-D-gluconate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde. EC:4.1.2.51|MetaCyc:DHDOGALDOL-RXN|RHEA:35583|MetaCyc:4.1.2.51-RXN go-plus.json KDG aldolase activity|2-keto-3-deoxygluconate aldolase activity http://purl.obolibrary.org/obo/GO_0061677 GO:0061678 biolink:BiologicalProcess Entner-Doudoroff pathway A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate. MetaCyc:Entner-Doudoroff-Pathways go-plus.json http://purl.obolibrary.org/obo/GO_0061678 GO:0061679 biolink:BiologicalProcess Entner-Doudoroff pathway through gluconate The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate. go-plus.json gluconate pathway http://purl.obolibrary.org/obo/GO_0061679 GO:0071021 biolink:CellularComponent U2-type post-spliceosomal complex A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6. go-plus.json yeast U2-type spliceosomal complex A2-3|major post-spliceosomal complex|mammalian U2-type spliceosomal complex C2|GT-AG post-spliceosomal complex http://purl.obolibrary.org/obo/GO_0071021 GO:0046065 biolink:BiologicalProcess dCTP metabolic process The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate. go-plus.json dCTP metabolism http://purl.obolibrary.org/obo/GO_0046065 GO:0046066 biolink:BiologicalProcess dGDP metabolic process The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). go-plus.json dGDP metabolism http://purl.obolibrary.org/obo/GO_0046066 GO:0071022 biolink:CellularComponent U12-type post-spliceosomal complex A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac. go-plus.json AT-AC post-spliceosomal complex|yeast U12-type spliceosomal complex A2-3|minor post-spliceosomal complex|mammalian U12-type spliceosomal complex C2 http://purl.obolibrary.org/obo/GO_0071022 GO:0046063 biolink:BiologicalProcess dCMP metabolic process The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate. go-plus.json dCMP metabolism http://purl.obolibrary.org/obo/GO_0046063 GO:0046064 biolink:BiologicalProcess dCMP biosynthetic process The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate. go-plus.json dCMP anabolism|dCMP synthesis|dCMP formation|dCMP biosynthesis http://purl.obolibrary.org/obo/GO_0046064 GO:0071020 biolink:CellularComponent post-spliceosomal complex A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5. go-plus.json yeast spliceosomal complex A2-3|mammalian spliceosomal complex C2 http://purl.obolibrary.org/obo/GO_0071020 GO:0046061 biolink:BiologicalProcess dATP catabolic process The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate). go-plus.json dATP degradation|dATP breakdown|dATP catabolism http://purl.obolibrary.org/obo/GO_0046061 GO:0046062 biolink:BiologicalProcess dCDP metabolic process The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate. go-plus.json dCDP metabolism http://purl.obolibrary.org/obo/GO_0046062 GO:1901228 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in heart development Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development. go-plus.json activation of global transcription from RNA polymerase II promoter involved in heart development|stimulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|up regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from Pol II promoter involved in heart development|positive regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of global transcription from RNA polymerase II promoter involved in heart development|activation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from Pol II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of global transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in heart development|activation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in cardiac development|up regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in heart development|up regulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in cardiac development|stimulation of global transcription from RNA polymerase II promoter involved in heart development|up regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of transcription from Pol II promoter involved in cardiac development|activation of transcription from RNA polymerase II promoter involved in heart development|up regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in heart development|upregulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|activation of transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in heart development http://purl.obolibrary.org/obo/GO_1901228 GO:1901229 biolink:BiologicalProcess regulation of non-canonical Wnt signaling pathway via JNK cascade Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade. go-plus.json regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|regulation of non-canonical Wnt receptor signaling pathway via JNK cascade http://purl.obolibrary.org/obo/GO_1901229 GO:0046060 biolink:BiologicalProcess dATP metabolic process The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate). go-plus.json dATP metabolism http://purl.obolibrary.org/obo/GO_0046060 GO:1901226 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development. go-plus.json up regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|activation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|upregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|upregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of global transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription regulation from Pol II promoter involved in cardiac development|up-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up-regulation of regulation of transcription from Pol II promoter involved in heart development|positive regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|activation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|activation of regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|up-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in cardiac development|activation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from Pol II promoter involved in dorsal vessel development|activation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up regulation of global transcription regulation from Pol II promoter involved in heart development|activation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|positive regulation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of global transcription from Pol II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in cardiac development|activation of global transcription regulation from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|positive regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up regulation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of global transcription regulation from Pol II promoter involved in cardiac development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|upregulation of global transcription regulation from Pol II promoter involved in heart development|activation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up regulation of global transcription regulation from Pol II promoter involved in cardiac development|positive regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|activation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of global transcription from Pol II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|upregulation of regulation of transcription from Pol II promoter involved in heart development|up-regulation of regulation of global transcription from Pol II promoter involved in heart development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of regulation of global transcription from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development http://purl.obolibrary.org/obo/GO_1901226 GO:1901227 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter involved in heart development Any negative regulation of transcription from RNA polymerase II promoter that is involved in heart development. go-plus.json negative regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in heart development|downregulation of transcription from RNA polymerase II promoter involved in cardiac development|inhibition of transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from Pol II promoter involved in heart development|negative regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of global transcription from Pol II promoter involved in heart development|down-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in heart development|down-regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of global transcription from RNA polymerase II promoter involved in heart development|down regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of global transcription from Pol II promoter involved in cardiac development|downregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of transcription from Pol II promoter involved in cardiac development|downregulation of transcription from RNA polymerase II promoter involved in heart development|downregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in cardiac development|down regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of global transcription from RNA polymerase II promoter involved in heart development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of global transcription from RNA polymerase II promoter involved in cardiac development|inhibition of global transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of transcription from RNA polymerase II promoter involved in cardiac development|inhibition of global transcription from RNA polymerase II promoter involved in cardiac development http://purl.obolibrary.org/obo/GO_1901227 GO:1901224 biolink:BiologicalProcess positive regulation of NIK/NF-kappaB signaling Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling. go-plus.json positive regulation of NF-kappaB import into nucleus|release of cytoplasmic sequestered NF-kappaB|positive regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|up regulation of p52-dependent NF-kappaB signaling|up regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|activation of non-canonical NF-KB signaling|positive regulation of p52-dependent NF-kappaB signaling|upregulation of noncanonical NF-kappaB signaling|release of NF-kappaB sequestered in cytoplasm|upregulation of NIK/NF-kappaB cascade|activation of p52-dependent NF-kappaB signaling|up-regulation of non-canonical NF-KB signaling|positive regulation of NIK/NF-kappaB cascade|up-regulation of noncanonical NF-kappaB signaling|upregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|activation of NIK/NF-kappaB cascade|negative regulation of cytoplasmic NF-kappaB storage|up-regulation of p52-dependent NF-kappaB signaling|up regulation of NIK/NF-kappaB cascade|activation of noncanonical NF-kappaB signaling|upregulation of non-canonical NF-KB signaling|up-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|positive regulation of noncanonical NF-kappaB signaling|upregulation of p52-dependent NF-kappaB signaling|up regulation of noncanonical NF-kappaB signaling|activation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|up-regulation of NIK/NF-kappaB cascade|up regulation of non-canonical NF-KB signaling|positive regulation of non-canonical NF-KB signaling http://purl.obolibrary.org/obo/GO_1901224 GO:1901225 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development. go-plus.json down regulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|inhibition of regulation of transcription from Pol II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of transcription from Pol II promoter involved in dorsal vessel development|inhibition of global transcription regulation from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of global transcription regulation from Pol II promoter involved in cardiac development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription regulation from Pol II promoter involved in heart development|down-regulation of global transcription regulation from Pol II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from Pol II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from Pol II promoter involved in heart development|negative regulation of regulation of transcription from Pol II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|down-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|inhibition of regulation of transcription from Pol II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in heart development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of global transcription regulation from Pol II promoter involved in cardiac development|down-regulation of global transcription regulation from Pol II promoter involved in cardiac development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of global transcription regulation from Pol II promoter involved in heart development|down regulation of regulation of global transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in heart development|down-regulation of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|downregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of regulation of transcription from Pol II promoter involved in heart development|downregulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|inhibition of global transcription regulation from Pol II promoter involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of regulation of transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|negative regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development http://purl.obolibrary.org/obo/GO_1901225 GO:0046069 biolink:BiologicalProcess cGMP catabolic process The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate. go-plus.json cGMP catabolism|cGMP breakdown|cGMP degradation http://purl.obolibrary.org/obo/GO_0046069 GO:1901222 biolink:BiologicalProcess regulation of NIK/NF-kappaB signaling Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling. go-plus.json regulation of NIK/NF-kappaB cascade|NF-kappaB import into nucleus|regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|NF-KB import into nucleus|regulation of non-canonical NF-KB signaling|regulation of NF-kappaB import into nucleus|regulation of p52-dependent NF-kappaB signaling|regulation of noncanonical NF-kappaB signaling http://purl.obolibrary.org/obo/GO_1901222 GO:1901223 biolink:BiologicalProcess negative regulation of NIK/NF-kappaB signaling Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling. go-plus.json down regulation of noncanonical NF-kappaB signaling|down-regulation of non-canonical NF-KB signaling|negative regulation of NF-kappaB import into nucleus|negative regulation of non-canonical NF-KB signaling|downregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|negative regulation of p52-dependent NF-kappaB signaling|down-regulation of p52-dependent NF-kappaB signaling|inhibition of noncanonical NF-kappaB signaling|down regulation of NIK/NF-kappaB cascade|down regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of NIK/NF-kappaB cascade|inhibition of non-canonical NF-KB signaling|negative regulation of NIK/NF-kappaB cascade|inhibition of noncanonical nuclear factor kappaB (NF-kappaB) pathway|inhibition of p52-dependent NF-kappaB signaling|negative regulation of noncanonical NF-kappaB signaling|down-regulation of noncanonical NF-kappaB signaling|down-regulation of NIK/NF-kappaB cascade|down regulation of non-canonical NF-KB signaling|inhibition of NIK/NF-kappaB cascade|down regulation of p52-dependent NF-kappaB signaling|downregulation of non-canonical NF-KB signaling|down-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|negative regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of noncanonical NF-kappaB signaling|downregulation of p52-dependent NF-kappaB signaling http://purl.obolibrary.org/obo/GO_1901223 GO:1901220 biolink:BiologicalProcess negative regulation of cardiac chamber morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. go-plus.json downregulation of heart chamber morphogenesis|down regulation of cardiac chamber morphogenesis|negative regulation of heart chamber morphogenesis|down-regulation of heart chamber morphogenesis|downregulation of cardiac chamber morphogenesis|inhibition of heart chamber morphogenesis|down-regulation of cardiac chamber morphogenesis|inhibition of cardiac chamber morphogenesis|down regulation of heart chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901220 GO:0046067 biolink:BiologicalProcess dGDP catabolic process The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). go-plus.json dGDP catabolism|dGDP degradation|dGDP breakdown http://purl.obolibrary.org/obo/GO_0046067 GO:0046068 biolink:BiologicalProcess cGMP metabolic process The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate. go-plus.json cGMP metabolism http://purl.obolibrary.org/obo/GO_0046068 GO:1901221 biolink:BiologicalProcess positive regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. go-plus.json up regulation of heart chamber morphogenesis|activation of heart chamber morphogenesis|upregulation of cardiac chamber morphogenesis|positive regulation of heart chamber morphogenesis|up regulation of cardiac chamber morphogenesis|activation of cardiac chamber morphogenesis|up-regulation of heart chamber morphogenesis|upregulation of heart chamber morphogenesis|up-regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901221 GO:1901230 biolink:BiologicalProcess negative regulation of non-canonical Wnt signaling pathway via JNK cascade Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade. go-plus.json down-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signalling pathway via JNK cascade http://purl.obolibrary.org/obo/GO_1901230 GO:0071029 biolink:BiologicalProcess nuclear ncRNA surveillance The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus. go-plus.json nuclear ncRNA quality control|nuclear aberrant ncRNA catabolic process http://purl.obolibrary.org/obo/GO_0071029 GO:0071027 biolink:BiologicalProcess nuclear RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus. go-plus.json nuclear RNA quality control|nuclear aberrant RNA catabolic process http://purl.obolibrary.org/obo/GO_0071027 GO:0071028 biolink:BiologicalProcess nuclear mRNA surveillance The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus. go-plus.json nuclear mRNA quality control|nuclear aberrant mRNA catabolic process http://purl.obolibrary.org/obo/GO_0071028 GO:0071025 biolink:BiologicalProcess RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs. go-plus.json aberrant RNA catabolic process|RNA quality control http://purl.obolibrary.org/obo/GO_0071025 GO:0071026 biolink:BiologicalProcess cytoplasmic RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm. go-plus.json cytoplasmic RNA quality control|cytoplasmic aberrant RNA catabolic process http://purl.obolibrary.org/obo/GO_0071026 GO:0071023 biolink:CellularComponent trans spliceosomal complex A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates. go-plus.json http://purl.obolibrary.org/obo/GO_0071023 GO:0071024 biolink:CellularComponent SL snRNP A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0071024 GO:0071010 biolink:CellularComponent prespliceosome A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex. go-plus.json mammalian spliceosomal complex A|prespliceosomal complex|yeast spliceosomal complex B http://purl.obolibrary.org/obo/GO_0071010 GO:0046076 biolink:BiologicalProcess dTTP catabolic process The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate. go-plus.json dTTP degradation|dTTP breakdown|dTTP catabolism http://purl.obolibrary.org/obo/GO_0046076 GO:0071011 biolink:CellularComponent precatalytic spliceosome A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs. go-plus.json mammalian spliceosomal complex B|yeast spliceosomal complex A2-1|mammalian spliceosomal complex B1 http://purl.obolibrary.org/obo/GO_0071011 GO:0046077 biolink:BiologicalProcess dUDP metabolic process The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate. go-plus.json dUDP metabolism http://purl.obolibrary.org/obo/GO_0046077 GO:0046074 biolink:BiologicalProcess dTMP catabolic process The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate. go-plus.json dTMP breakdown|dTMP catabolism|dTMP degradation http://purl.obolibrary.org/obo/GO_0046074 GO:0046075 biolink:BiologicalProcess dTTP metabolic process The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate. go-plus.json dTTP metabolism http://purl.obolibrary.org/obo/GO_0046075 GO:0046072 biolink:BiologicalProcess dTDP metabolic process The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate. go-plus.json dTDP metabolism http://purl.obolibrary.org/obo/GO_0046072 GO:0046073 biolink:BiologicalProcess dTMP metabolic process The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). go-plus.json dTMP metabolism http://purl.obolibrary.org/obo/GO_0046073 GO:0046070 biolink:BiologicalProcess dGTP metabolic process The chemical reactions and pathways involving dGTP, guanosine triphosphate. go-plus.json dGTP metabolism http://purl.obolibrary.org/obo/GO_0046070 GO:1901239 biolink:MolecularActivity malonate(1-) transmembrane transporter activity Enables the transfer of malonate(1-) from one side of a membrane to the other. RHEA:33115 go-plus.json malonic acid uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901239 GO:0046071 biolink:BiologicalProcess dGTP biosynthetic process The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate. go-plus.json dGTP synthesis|dGTP formation|dGTP biosynthesis|dGTP anabolism http://purl.obolibrary.org/obo/GO_0046071 GO:1901237 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901237 GO:1901238 biolink:MolecularActivity ABC-type tungstate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out). EC:7.3.2.6|RHEA:35027 go-plus.json ATPase-coupled tungstate transmembrane transporter activity|tungstate transmembrane-transporting ATPase activity|tungstate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901238 GO:1901235 biolink:MolecularActivity (R)-carnitine transmembrane transporter activity Enables the transfer of (R)-carnitine from one side of a membrane to the other. RHEA:34959 go-plus.json http://purl.obolibrary.org/obo/GO_1901235 GO:1901236 biolink:MolecularActivity 4-(trimethylammonio)butanoate transmembrane transporter activity Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other. RHEA:32835 go-plus.json http://purl.obolibrary.org/obo/GO_1901236 GO:0061690 biolink:MolecularActivity lipoamidase activity Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein. MetaCyc:RXN-13031 go-plus.json lipoyl-X-hydrolase http://purl.obolibrary.org/obo/GO_0061690 GO:0061691 biolink:BiologicalProcess detoxification of hydrogen peroxide Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration. go-plus.json http://purl.obolibrary.org/obo/GO_0061691 GO:1901233 biolink:BiologicalProcess negative regulation of convergent extension involved in axis elongation Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation. go-plus.json down-regulation of convergent extension involved in axis elongation|downregulation of convergent extension involved in axis elongation|down regulation of convergent extension involved in axis elongation|inhibition of convergent extension involved in axis elongation http://purl.obolibrary.org/obo/GO_1901233 GO:0061692 biolink:BiologicalProcess cellular detoxification of hydrogen peroxide Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration. go-plus.json http://purl.obolibrary.org/obo/GO_0061692 GO:1901234 biolink:BiologicalProcess positive regulation of convergent extension involved in axis elongation Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation. go-plus.json up-regulation of convergent extension involved in axis elongation|activation of convergent extension involved in axis elongation|up regulation of convergent extension involved in axis elongation|upregulation of convergent extension involved in axis elongation http://purl.obolibrary.org/obo/GO_1901234 GO:1901231 biolink:BiologicalProcess positive regulation of non-canonical Wnt signaling pathway via JNK cascade Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade. go-plus.json up-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|activation of non-canonical Wnt receptor signaling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|positive regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|activation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signaling pathway via JNK cascade http://purl.obolibrary.org/obo/GO_1901231 GO:0061693 biolink:MolecularActivity alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine. RHEA:34679|EC:2.7.8.37|MetaCyc:RXN0-6732 go-plus.json http://purl.obolibrary.org/obo/GO_0061693 GO:0046078 biolink:BiologicalProcess dUMP metabolic process The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate). go-plus.json dUMP metabolism http://purl.obolibrary.org/obo/GO_0046078 GO:0046079 biolink:BiologicalProcess dUMP catabolic process The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate. go-plus.json dUMP breakdown|dUMP catabolism|dUMP degradation http://purl.obolibrary.org/obo/GO_0046079 GO:1901232 biolink:BiologicalProcess regulation of convergent extension involved in axis elongation Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation. go-plus.json http://purl.obolibrary.org/obo/GO_1901232 GO:0061694 biolink:CellularComponent alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061694 GO:0061695 biolink:CellularComponent transferase complex, transferring phosphorus-containing groups A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). go-plus.json http://purl.obolibrary.org/obo/GO_0061695 GO:1901240 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901240 GO:0061696 biolink:CellularComponent pituitary gonadotropin complex A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function. go-plus.json http://purl.obolibrary.org/obo/GO_0061696 GO:1901241 biolink:MolecularActivity 4-hydroxyphenylacetate transmembrane transporter activity Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other. RHEA:33175 go-plus.json http://purl.obolibrary.org/obo/GO_1901241 GO:0061697 biolink:MolecularActivity protein-glutaryllysine deglutarylase activity Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. RHEA:47664 go-plus.json http://purl.obolibrary.org/obo/GO_0061697 GO:0061698 biolink:BiologicalProcess protein deglutarylation The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0061698 GO:0061699 biolink:BiologicalProcess peptidyl-lysine deglutarylation The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0061699 GO:0071018 biolink:CellularComponent U12-type catalytic step 2 spliceosome A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs. go-plus.json mammalian U12-type spliceosomal complex C|yeast U12-type spliceosomal complex A2-2|minor catalytic step 2 spliceosome|AT-AC catalytic step 2 spliceosome|mammalian U12-type spliceosomal complex C1 http://purl.obolibrary.org/obo/GO_0071018 GO:0071019 biolink:CellularComponent U12-type post-mRNA release spliceosomal complex A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs. go-plus.json minor post-mRNA release spliceosomal complex|AT-AC post-mRNA release spliceosomal complex|mammalian U12-type spliceosomal complex I http://purl.obolibrary.org/obo/GO_0071019 GO:0046080 biolink:BiologicalProcess dUTP metabolic process The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate. go-plus.json dUTP metabolism http://purl.obolibrary.org/obo/GO_0046080 GO:0071016 biolink:CellularComponent U12-type precatalytic spliceosome A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs. go-plus.json mammalian U12-type spliceosomal complex B|yeast U12-type spliceosomal complex A2-1|mammalian U12-type spliceosomal complex B1|minor precatalytic spliceosome|AT-AC precatalytic spliceosome http://purl.obolibrary.org/obo/GO_0071016 GO:0071017 biolink:CellularComponent U12-type catalytic step 1 spliceosome A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs. go-plus.json minor catalytic step 1 spliceosome|AT-AC catalytic step 1 spliceosome|yeast U12-type spliceosomal complex A1|mammalian U12-type spliceosomal complex B2|U12-type activated spliceosome|mammalian U12-type spliceosomal complex B* http://purl.obolibrary.org/obo/GO_0071017 GO:0071014 biolink:CellularComponent post-mRNA release spliceosomal complex A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5. go-plus.json mammalian spliceosomal complex I http://purl.obolibrary.org/obo/GO_0071014 GO:0071015 biolink:CellularComponent U12-type prespliceosome A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. go-plus.json mammalian U12-type spliceosomal complex A|minor prespliceosome|AT-AC prespliceosome|yeast U12-type spliceosomal complex B http://purl.obolibrary.org/obo/GO_0071015 GO:0071012 biolink:CellularComponent catalytic step 1 spliceosome A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs. go-plus.json activated spliceosome|mammalian spliceosomal complex B2|yeast spliceosomal complex A1|mammalian spliceosomal complex B* http://purl.obolibrary.org/obo/GO_0071012 GO:0071013 biolink:CellularComponent catalytic step 2 spliceosome A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. go-plus.json mammalian spliceosomal complex C|yeast spliceosomal complex A2-2|mammalian spliceosomal complex C1 http://purl.obolibrary.org/obo/GO_0071013 GO:0071043 biolink:BiologicalProcess CUT metabolic process The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome. go-plus.json http://purl.obolibrary.org/obo/GO_0071043 GO:0046087 biolink:BiologicalProcess cytidine metabolic process The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside. go-plus.json cytidine metabolism http://purl.obolibrary.org/obo/GO_0046087 GO:0022032 biolink:BiologicalProcess telencephalon oligodendrocyte cell migration The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022032 GO:0071044 biolink:BiologicalProcess histone mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0071044 CHEBI:9053 biolink:ChemicalSubstance sclareol go-plus.json http://purl.obolibrary.org/obo/CHEBI_9053 chebi_ph7_3 GO:0046088 biolink:BiologicalProcess cytidine biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside. go-plus.json cytidine anabolism|cytidine synthesis|cytidine formation|cytidine biosynthesis http://purl.obolibrary.org/obo/GO_0046088 GO:0022033 biolink:BiologicalProcess telencephalon microglial cell migration The orderly movement of microglial cells through the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0022033 GO:0071041 biolink:BiologicalProcess antisense RNA transcript catabolic process The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product. go-plus.json http://purl.obolibrary.org/obo/GO_0071041 GO:0022034 biolink:BiologicalProcess rhombomere cell proliferation The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022034 GO:0046085 biolink:BiologicalProcess adenosine metabolic process The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. go-plus.json adenosine metabolism http://purl.obolibrary.org/obo/GO_0046085 GO:0071042 biolink:BiologicalProcess nuclear polyadenylation-dependent mRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA. go-plus.json nuclear poly(A)-dependent mRNA catabolic process http://purl.obolibrary.org/obo/GO_0071042 GO:0022035 biolink:BiologicalProcess rhombomere cell migration The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. go-plus.json http://purl.obolibrary.org/obo/GO_0022035 GO:0046086 biolink:BiologicalProcess adenosine biosynthetic process The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. go-plus.json adenosine formation|adenosine biosynthesis|adenosine anabolism|adenosine synthesis http://purl.obolibrary.org/obo/GO_0046086 GO:0022036 biolink:BiologicalProcess rhombomere cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell. go-plus.json http://purl.obolibrary.org/obo/GO_0022036 GO:0046083 biolink:BiologicalProcess adenine metabolic process The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine. go-plus.json adenine metabolism http://purl.obolibrary.org/obo/GO_0046083 GO:0022037 biolink:BiologicalProcess metencephalon development The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0022037 GO:0071040 biolink:BiologicalProcess nuclear polyadenylation-dependent antisense transcript catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript. go-plus.json nuclear poly(A)-dependent antisense transcript catabolic process http://purl.obolibrary.org/obo/GO_0071040 GO:0046084 biolink:BiologicalProcess adenine biosynthetic process The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine. go-plus.json adenine biosynthesis|adenine anabolism|adenine synthesis|adenine formation http://purl.obolibrary.org/obo/GO_0046084 GO:0046081 biolink:BiologicalProcess dUTP catabolic process The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate. go-plus.json dUTP degradation|dUTP breakdown|dUTP catabolism http://purl.obolibrary.org/obo/GO_0046081 GO:0022038 biolink:BiologicalProcess corpus callosum development The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. go-plus.json http://purl.obolibrary.org/obo/GO_0022038 GO:0046082 biolink:BiologicalProcess 5-methylcytosine biosynthetic process The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA. go-plus.json 5-methylcytosine biosynthesis|5-methylcytosine anabolism|5-methylcytosine synthesis|5-methylcytosine formation http://purl.obolibrary.org/obo/GO_0046082 OBO:GOCHE_52208 biolink:OntologyClass substance with biophysical role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_52208 1_STAR GO:1901248 biolink:BiologicalProcess positive regulation of lung ciliated cell differentiation Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation. go-plus.json up regulation of lung ciliated cell differentiation|upregulation of lung ciliated cell differentiation|up-regulation of lung ciliated cell differentiation|activation of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_1901248 GO:1901249 biolink:BiologicalProcess regulation of lung goblet cell differentiation Any process that modulates the frequency, rate or extent of lung goblet cell differentiation. go-plus.json regulation of pulmonary goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901249 GO:1901246 biolink:BiologicalProcess regulation of lung ciliated cell differentiation Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1901246 OBO:GOCHE_52206 biolink:OntologyClass substance with biochemical role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_52206 3_STAR GO:1901247 biolink:BiologicalProcess negative regulation of lung ciliated cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation. go-plus.json down-regulation of lung ciliated cell differentiation|downregulation of lung ciliated cell differentiation|down regulation of lung ciliated cell differentiation|inhibition of lung ciliated cell differentiation http://purl.obolibrary.org/obo/GO_1901247 GO:1901244 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter to protect the cell or organism in response to the presence of a fungus. go-plus.json activation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of global transcription from Pol II promoter involved in defense response to fungus|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of global transcription from Pol II promoter involved in defense response to fungi|activation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from Pol II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from Pol II promoter involved in defense response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|activation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|activation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of global transcription from Pol II promoter involved in defence response to fungus|positive regulation of global transcription from Pol II promoter involved in defence response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from Pol II promoter involved in defense response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from Pol II promoter involved in defence response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|activation of transcription from RNA polymerase II promoter involved in defense response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|activation of transcription from RNA polymerase II promoter involved in defense response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungi http://purl.obolibrary.org/obo/GO_1901244 GO:1901245 biolink:BiologicalProcess positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling. go-plus.json BCR-induced TLR9 recruitment|positive regulation of toll-like receptor 9 signaling pathway by BCR receptor internalization|positive regulation of TLR9 signaling pathway by BCR endocytosis|positive regulation of toll-like receptor 9 signalling pathway by BCR endocytosis|positive regulation of toll-like receptor 9 signalling pathway by BCR receptor internalization|positive regulation of TLR9 signaling pathway by B cell receptor internalization|positive regulation of toll-like receptor 9 signalling pathway by B cell receptor internalization|positive regulation of TLR9 signaling pathway by BCR receptor internalization|positive regulation of toll-like receptor 9 signaling pathway by BCR endocytosis http://purl.obolibrary.org/obo/GO_1901245 GO:1901242 biolink:MolecularActivity ABC-type doxorubicin transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out). TC:3.A.1.105.1 go-plus.json ATPase-coupled doxorubicin transmembrane transporter activity|doxorubicin transmembrane-transporting ATPase activity http://purl.obolibrary.org/obo/GO_1901242 GO:0022030 biolink:BiologicalProcess telencephalon glial cell migration The orderly movement of glial cells through the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0022030 GO:0046089 biolink:BiologicalProcess cytosine biosynthetic process The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. go-plus.json cytosine anabolism|cytosine synthesis|cytosine formation|cytosine biosynthesis http://purl.obolibrary.org/obo/GO_0046089 GO:0022031 biolink:BiologicalProcess telencephalon astrocyte cell migration The orderly movement of an astrocyte cell through the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0022031 GO:1901243 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901243 GO:1901251 biolink:BiologicalProcess positive regulation of lung goblet cell differentiation Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation. go-plus.json upregulation of pulmonary goblet cell differentiation|upregulation of lung goblet cell differentiation|up regulation of pulmonary goblet cell differentiation|positive regulation of pulmonary goblet cell differentiation|activation of pulmonary goblet cell differentiation|up-regulation of lung goblet cell differentiation|activation of lung goblet cell differentiation|up-regulation of pulmonary goblet cell differentiation|up regulation of lung goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901251 OBO:GOCHE_52211 biolink:OntologyClass substance with physiological role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_52211 1_STAR GO:1901252 biolink:BiologicalProcess regulation of intracellular transport of viral material Any process that modulates the frequency, rate or extent of egress of virus within host cell. go-plus.json regulation of viral egress|regulation of movement of virus within host cell|regulation of egress of virus within host cell http://purl.obolibrary.org/obo/GO_1901252 GO:1901250 biolink:BiologicalProcess negative regulation of lung goblet cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation. go-plus.json downregulation of lung goblet cell differentiation|down regulation of lung goblet cell differentiation|inhibition of lung goblet cell differentiation|down regulation of pulmonary goblet cell differentiation|downregulation of pulmonary goblet cell differentiation|down-regulation of pulmonary goblet cell differentiation|negative regulation of pulmonary goblet cell differentiation|down-regulation of lung goblet cell differentiation|inhibition of pulmonary goblet cell differentiation http://purl.obolibrary.org/obo/GO_1901250 OBO:GOCHE_52210 biolink:OntologyClass substance with pharmacological role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_52210 3_STAR GO:0046090 biolink:BiologicalProcess deoxyadenosine metabolic process The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. go-plus.json deoxyadenosine metabolism http://purl.obolibrary.org/obo/GO_0046090 GO:0046091 biolink:BiologicalProcess deoxyadenosine biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. go-plus.json deoxyadenosine biosynthesis|deoxyadenosine anabolism|deoxyadenosine synthesis|deoxyadenosine formation http://purl.obolibrary.org/obo/GO_0046091 GO:0071049 biolink:BiologicalProcess nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0071049 GO:0071047 biolink:BiologicalProcess polyadenylation-dependent mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA. go-plus.json poly(A)-dependent mRNA catabolic process http://purl.obolibrary.org/obo/GO_0071047 GO:0071048 biolink:BiologicalProcess nuclear retention of unspliced pre-mRNA at the site of transcription The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0071048 GO:0071045 biolink:BiologicalProcess nuclear histone mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0071045 GO:0071046 biolink:BiologicalProcess nuclear polyadenylation-dependent ncRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA. go-plus.json nuclear poly(A)-dependent ncRNA catabolic process http://purl.obolibrary.org/obo/GO_0071046 GO:0022021 biolink:BiologicalProcess caudal ganglionic eminence cell proliferation The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022021 GO:0046098 biolink:BiologicalProcess guanine metabolic process The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. go-plus.json guanine metabolism http://purl.obolibrary.org/obo/GO_0046098 GO:0071032 biolink:BiologicalProcess nuclear mRNA surveillance of mRNP export The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm. go-plus.json nuclear mRNA quality control of mRNAs in aberrant mRNPs|nuclear mRNA catabolic process of mRNAs in aberrant mRNPs http://purl.obolibrary.org/obo/GO_0071032 CHEBI:145992 biolink:ChemicalSubstance orlandin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145992 chebi_ph7_3 GO:0022022 biolink:BiologicalProcess septal cell proliferation The multiplication or reproduction of septal cells, resulting in the expansion of a cell population. go-plus.json septum cell proliferation http://purl.obolibrary.org/obo/GO_0022022 GO:0046099 biolink:BiologicalProcess guanine biosynthetic process The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. go-plus.json guanine biosynthesis|guanine anabolism|guanine synthesis|guanine formation http://purl.obolibrary.org/obo/GO_0046099 GO:0071033 biolink:BiologicalProcess nuclear retention of pre-mRNA at the site of transcription The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0071033 GO:0071030 biolink:BiologicalProcess nuclear mRNA surveillance of spliceosomal pre-mRNA splicing The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus. go-plus.json nuclear RNA catabolic process of incorrectly spliced pre-mRNA|nuclear mRNA quality control of incorrectly spliced pre-mRNA http://purl.obolibrary.org/obo/GO_0071030 GO:0046096 biolink:BiologicalProcess deoxyuridine metabolic process The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA. go-plus.json deoxyuridine metabolism http://purl.obolibrary.org/obo/GO_0046096 GO:0022023 biolink:BiologicalProcess radial glial cell fate commitment in forebrain The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0022023 GO:0046097 biolink:BiologicalProcess deoxyuridine biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA. go-plus.json deoxyuridine anabolism|deoxyuridine synthesis|deoxyuridine formation|deoxyuridine biosynthesis http://purl.obolibrary.org/obo/GO_0046097 GO:0022024 biolink:BiologicalProcess BMP signaling pathway involved in forebrain neuron fate commitment A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. go-plus.json bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment|BMP signalling pathway involved in forebrain neuron fate commitment|bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment http://purl.obolibrary.org/obo/GO_0022024 GO:0071031 biolink:BiologicalProcess nuclear mRNA surveillance of mRNA 3'-end processing The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus. go-plus.json nuclear mRNA quality control of mRNAs with aberrant 3'-ends|nuclear mRNA catabolic process of mRNA with aberrant 3'-ends http://purl.obolibrary.org/obo/GO_0071031 CHEBI:9066 biolink:ChemicalSubstance L-adenosylselenomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9066 GO:0046094 biolink:BiologicalProcess deoxyinosine metabolic process The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside. go-plus.json deoxyinosine metabolism http://purl.obolibrary.org/obo/GO_0046094 GO:0022025 biolink:BiologicalProcess leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. go-plus.json leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment http://purl.obolibrary.org/obo/GO_0022025 GO:0046095 biolink:BiologicalProcess deoxyinosine biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside. go-plus.json deoxyinosine biosynthesis|deoxyinosine anabolism|deoxyinosine synthesis|deoxyinosine formation http://purl.obolibrary.org/obo/GO_0046095 GO:0022026 biolink:BiologicalProcess epidermal growth factor signaling pathway involved in forebrain neuron fate commitment The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. go-plus.json epidermal growth factor signalling pathway involved in forebrain neuron fate commitment http://purl.obolibrary.org/obo/GO_0022026 GO:0046092 biolink:BiologicalProcess deoxycytidine metabolic process The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA. go-plus.json deoxycytidine metabolism http://purl.obolibrary.org/obo/GO_0046092 GO:0022027 biolink:BiologicalProcess interkinetic nuclear migration The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0022027 GO:0046093 biolink:BiologicalProcess deoxycytidine biosynthetic process The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA. go-plus.json deoxycytidine anabolism|deoxycytidine synthesis|deoxycytidine formation|deoxycytidine biosynthesis http://purl.obolibrary.org/obo/GO_0046093 CHEBI:9062 biolink:ChemicalSubstance scutellarein go-plus.json http://purl.obolibrary.org/obo/CHEBI_9062 GO:0022028 biolink:BiologicalProcess tangential migration from the subventricular zone to the olfactory bulb The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. go-plus.json rostral migratory stream migration http://purl.obolibrary.org/obo/GO_0022028 GO:1901259 biolink:BiologicalProcess chloroplast rRNA processing Any rRNA processing that takes place in chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_1901259 GO:1901257 biolink:BiologicalProcess negative regulation of macrophage colony-stimulating factor production Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production. go-plus.json down regulation of macrophage colony-stimulating factor production|downregulation of macrophage colony-stimulating factor production|downregulation of M-CSF production|down regulation of M-CSF production|down-regulation of macrophage colony-stimulating factor production|inhibition of M-CSF production|inhibition of macrophage colony-stimulating factor production|down-regulation of M-CSF production|negative regulation of M-CSF production http://purl.obolibrary.org/obo/GO_1901257 GO:1901258 biolink:BiologicalProcess positive regulation of macrophage colony-stimulating factor production Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production. go-plus.json positive regulation of M-CSF production|up regulation of M-CSF production|up regulation of macrophage colony-stimulating factor production|activation of macrophage colony-stimulating factor production|upregulation of M-CSF production|up-regulation of macrophage colony-stimulating factor production|up-regulation of M-CSF production|activation of M-CSF production|upregulation of macrophage colony-stimulating factor production http://purl.obolibrary.org/obo/GO_1901258 GO:1901255 biolink:BiologicalProcess nucleotide-excision repair involved in interstrand cross-link repair Any nucleotide-excision repair that is involved in interstrand cross-link repair. go-plus.json nucleotide-excision repair involved in ICL repair|NER involved in ICL repair|NER involved in interstrand cross-link repair http://purl.obolibrary.org/obo/GO_1901255 GO:1901256 biolink:BiologicalProcess regulation of macrophage colony-stimulating factor production Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production. go-plus.json regulation of M-CSF production http://purl.obolibrary.org/obo/GO_1901256 GO:1901253 biolink:BiologicalProcess negative regulation of intracellular transport of viral material Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material. go-plus.json down-regulation of movement of virus within host cell|negative regulation of movement of virus within host cell|down regulation of viral egress|downregulation of egress of virus within host cell|down regulation of egress of virus within host cell|downregulation of movement of virus within host cell|inhibition of egress of virus within host cell|inhibition of viral egress|down regulation of movement of virus within host cell|negative regulation of egress of virus within host cell|inhibition of movement of virus within host cell|negative regulation of viral egress|down-regulation of viral egress|down-regulation of egress of virus within host cell|downregulation of viral egress http://purl.obolibrary.org/obo/GO_1901253 GO:1901254 biolink:BiologicalProcess positive regulation of intracellular transport of viral material Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material. go-plus.json up regulation of egress of virus within host cell|positive regulation of movement of virus within host cell|upregulation of viral egress|up regulation of movement of virus within host cell|upregulation of egress of virus within host cell|up-regulation of viral egress|upregulation of movement of virus within host cell|up-regulation of egress of virus within host cell|positive regulation of egress of virus within host cell|activation of viral egress|activation of egress of virus within host cell|up-regulation of movement of virus within host cell|positive regulation of viral egress|up regulation of viral egress|activation of movement of virus within host cell http://purl.obolibrary.org/obo/GO_1901254 GO:0022020 biolink:BiologicalProcess medial ganglionic eminence cell proliferation The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022020 GO:1901262 biolink:BiologicalProcess negative regulation of sorocarp spore cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation. go-plus.json inhibition of sorocarp spore cell differentiation|down regulation of sorocarp spore cell differentiation|downregulation of sorocarp spore cell differentiation|down-regulation of sorocarp spore cell differentiation http://purl.obolibrary.org/obo/GO_1901262 GO:1901263 biolink:BiologicalProcess positive regulation of sorocarp spore cell differentiation Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation. go-plus.json up-regulation of sorocarp spore cell differentiation|upregulation of sorocarp spore cell differentiation|up regulation of sorocarp spore cell differentiation|activation of sorocarp spore cell differentiation http://purl.obolibrary.org/obo/GO_1901263 GO:1901260 biolink:BiologicalProcess peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification. go-plus.json EF-P lysine hydroxylation http://purl.obolibrary.org/obo/GO_1901260 GO:1901261 biolink:BiologicalProcess regulation of sorocarp spore cell differentiation Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1901261 CHEBI:131367 biolink:ChemicalSubstance 3-hydroxy-3-butenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131367 GO:0022029 biolink:BiologicalProcess telencephalon cell migration The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0022029 GO:0071038 biolink:BiologicalProcess nuclear polyadenylation-dependent tRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA. go-plus.json nuclear poly(A)-dependent tRNA catabolic process http://purl.obolibrary.org/obo/GO_0071038 GO:0071039 biolink:BiologicalProcess nuclear polyadenylation-dependent CUT catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT. go-plus.json nuclear poly(A)-dependent CUT catabolic process http://purl.obolibrary.org/obo/GO_0071039 GO:0071036 biolink:BiologicalProcess nuclear polyadenylation-dependent snoRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA. go-plus.json nuclear poly(A)-dependent snoRNA catabolic process http://purl.obolibrary.org/obo/GO_0071036 GO:0071037 biolink:BiologicalProcess nuclear polyadenylation-dependent snRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA. go-plus.json nuclear poly(A)-dependent snRNA catabolic process http://purl.obolibrary.org/obo/GO_0071037 GO:0071034 biolink:BiologicalProcess CUT catabolic process The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs). go-plus.json cryptic unstable transcript catabolic process http://purl.obolibrary.org/obo/GO_0071034 GO:0071035 biolink:BiologicalProcess nuclear polyadenylation-dependent rRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA. go-plus.json nuclear poly(A)-dependent rRNA catabolic process http://purl.obolibrary.org/obo/GO_0071035 GO:0022010 biolink:BiologicalProcess central nervous system myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. go-plus.json myelination in central nervous system http://purl.obolibrary.org/obo/GO_0022010 GO:0071065 biolink:CellularComponent alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1. go-plus.json ITGA9-ITGB1-VCAM1 complex http://purl.obolibrary.org/obo/GO_0071065 GO:0022011 biolink:BiologicalProcess myelination in peripheral nervous system The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. go-plus.json peripheral nervous system myelination http://purl.obolibrary.org/obo/GO_0022011 GO:0071066 biolink:BiologicalProcess detection of mechanical stimulus involved in sensory perception of wind The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal. go-plus.json perception of wind, sensory detection of mechanical stimulus|perception of wind, detection of mechanical stimulus|perception of wind, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during perception of wind|detection of mechanical stimulus involved in sensory perception of air flow|detection of wind|sensory detection of mechanical stimulus during perception of wind|sensory transduction of wind http://purl.obolibrary.org/obo/GO_0071066 GO:0071063 biolink:BiologicalProcess sensory perception of wind The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal. go-plus.json perception of wind|sensory perception of air flow http://purl.obolibrary.org/obo/GO_0071063 GO:0022012 biolink:BiologicalProcess subpallium cell proliferation in forebrain The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022012 GO:0071064 biolink:CellularComponent alphaE-beta7 integrin-E-cadherin complex A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin. go-plus.json ITGAE-ITGB7-CDH1 complex http://purl.obolibrary.org/obo/GO_0071064 GO:0022013 biolink:BiologicalProcess pallium cell proliferation in forebrain The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022013 GO:0071061 biolink:CellularComponent alpha6-beta4 integrin-CD151 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151. go-plus.json ITGA6-ITGB4-CD151 complex http://purl.obolibrary.org/obo/GO_0071061 GO:0022014 biolink:BiologicalProcess obsolete radial glial cell division in subpallium OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0022014 GO:0071062 biolink:CellularComponent alphav-beta3 integrin-vitronectin complex A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin. go-plus.json ITGAV-ITGB3-VTN complex http://purl.obolibrary.org/obo/GO_0071062 GO:0022015 biolink:BiologicalProcess radial glial cell division in pallium The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0022015 GO:0022016 biolink:BiologicalProcess pallium glioblast division The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells. go-plus.json glioblast cell division in pallium http://purl.obolibrary.org/obo/GO_0022016 GO:0071060 biolink:CellularComponent alpha7-beta1 integrin-CD151 complex A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151. go-plus.json ITGA7-ITGB1-CD151 complex http://purl.obolibrary.org/obo/GO_0071060 GO:0022017 biolink:BiologicalProcess neuroblast division in pallium The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0022017 GO:1901268 biolink:BiologicalProcess cephalosporin C biosynthetic process The chemical reactions and pathways resulting in the formation of cephalosporin C. go-plus.json cephalosporin C anabolism|cephalosporin C synthesis|cephalosporin C formation|cephalosporin C biosynthesis http://purl.obolibrary.org/obo/GO_1901268 GO:1901269 biolink:BiologicalProcess lipooligosaccharide metabolic process The chemical reactions and pathways involving lipooligosaccharide. go-plus.json lipooligosaccharide metabolism http://purl.obolibrary.org/obo/GO_1901269 GO:1901266 biolink:BiologicalProcess cephalosporin C metabolic process The chemical reactions and pathways involving cephalosporin C. go-plus.json cephalosporin C metabolism http://purl.obolibrary.org/obo/GO_1901266 GO:1901267 biolink:BiologicalProcess cephalosporin C catabolic process The chemical reactions and pathways resulting in the breakdown of cephalosporin C. go-plus.json cephalosporin C catabolism|cephalosporin C degradation|cephalosporin C breakdown http://purl.obolibrary.org/obo/GO_1901267 GO:1901264 biolink:BiologicalProcess carbohydrate derivative transport The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901264 GO:1901265 biolink:MolecularActivity nucleoside phosphate binding Binding to nucleoside phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1901265 GO:1901273 biolink:BiologicalProcess 2-dehydro-3-deoxy-D-gluconic acid catabolic process The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid. go-plus.json 2-dehydro-3-deoxy-D-gluconic acid breakdown|2-dehydro-3-deoxy-D-gluconic acid catabolism|2-dehydro-3-deoxy-D-gluconic acid degradation http://purl.obolibrary.org/obo/GO_1901273 GO:1901274 biolink:BiologicalProcess 2-dehydro-3-deoxy-D-gluconic acid biosynthetic process The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid. go-plus.json 2-dehydro-3-deoxy-D-gluconic acid biosynthesis|2-dehydro-3-deoxy-D-gluconic acid anabolism|2-dehydro-3-deoxy-D-gluconic acid synthesis|2-dehydro-3-deoxy-D-gluconic acid formation http://purl.obolibrary.org/obo/GO_1901274 GO:1901271 biolink:BiologicalProcess lipooligosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of lipooligosaccharide. go-plus.json lipooligosaccharide biosynthesis|lipooligosaccharide anabolism|lipooligosaccharide synthesis|lipooligosaccharide formation http://purl.obolibrary.org/obo/GO_1901271 GO:1901272 biolink:BiologicalProcess 2-dehydro-3-deoxy-D-gluconic acid metabolic process The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid. go-plus.json 2-dehydro-3-deoxy-D-gluconic acid metabolism http://purl.obolibrary.org/obo/GO_1901272 GO:1901270 biolink:BiologicalProcess lipooligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide. go-plus.json lipooligosaccharide breakdown|lipooligosaccharide catabolism|lipooligosaccharide degradation http://purl.obolibrary.org/obo/GO_1901270 GO:0022018 biolink:BiologicalProcess lateral ganglionic eminence cell proliferation The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022018 CHEBI:145989 biolink:ChemicalSubstance 3-phosphonatoshikimate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145989 chebi_ph7_3 GO:0022019 biolink:BiologicalProcess dorsal lateral ganglionic eminence cell proliferation The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0022019 GO:0071069 biolink:CellularComponent alpha4-beta1 integrin-thrombospondin-1 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1. go-plus.json ITGA4-ITGB1-THBS1 complex http://purl.obolibrary.org/obo/GO_0071069 GO:0071067 biolink:CellularComponent alphav-beta3 integrin-ADAM23 complex A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23. go-plus.json ITGAV-ITGB3-ADAM23 complex http://purl.obolibrary.org/obo/GO_0071067 GO:0071068 biolink:CellularComponent alpha9-beta1 integrin-ADAM12 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12. go-plus.json ITGA9-ITGB1-ADAM12 complex http://purl.obolibrary.org/obo/GO_0071068 GO:0071054 biolink:CellularComponent alpha9-beta1 integrin-ADAM3 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3. go-plus.json ITGA9-ITGB1-ADAM3 complex http://purl.obolibrary.org/obo/GO_0071054 GO:0071055 biolink:CellularComponent alpha9-beta1 integrin-ADAM9 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9. go-plus.json ITGA9-ITGB1-ADAM9 complex http://purl.obolibrary.org/obo/GO_0071055 GO:0022000 biolink:BiologicalProcess forebrain induction by the anterior neural ridge The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate. go-plus.json http://purl.obolibrary.org/obo/GO_0022000 GO:0071052 biolink:CellularComponent alpha9-beta1 integrin-ADAM1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1. go-plus.json ITGA9-ITGB1-ADAM1 complex http://purl.obolibrary.org/obo/GO_0071052 GO:0022001 biolink:BiologicalProcess negative regulation of anterior neural cell fate commitment of the neural plate Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate. go-plus.json down regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate of the neural plate|caudalization of neural plate|downregulation of anterior neural cell fate of the neural plate|down-regulation of anterior neural cell fate of the neural plate|posteriorization|inhibition of anterior neural cell fate of the neural plate http://purl.obolibrary.org/obo/GO_0022001 GO:0071053 biolink:CellularComponent alpha9-beta1 integrin-ADAM2 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2. go-plus.json ITGA9-ITGB1-ADAM2 complex http://purl.obolibrary.org/obo/GO_0071053 GO:0022002 biolink:BiologicalProcess negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell. go-plus.json Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway|Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway|Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate http://purl.obolibrary.org/obo/GO_0022002 GO:0022003 biolink:BiologicalProcess negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. go-plus.json fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate http://purl.obolibrary.org/obo/GO_0022003 GO:0071050 biolink:BiologicalProcess sno(s)RNA polyadenylation The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA class molecule (referred to as an sRNA in Archaea). In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation. go-plus.json sRNA polyadenylation|snoRNA polyadenylation http://purl.obolibrary.org/obo/GO_0071050 GO:0022004 biolink:BiologicalProcess midbrain-hindbrain boundary maturation during brain development A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json http://purl.obolibrary.org/obo/GO_0022004 GO:0071051 biolink:BiologicalProcess polyadenylation-dependent snoRNA 3'-end processing Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA. go-plus.json poly(A)-dependent snoRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0071051 GO:0022005 biolink:BiologicalProcess midbrain-hindbrain boundary maturation during neural plate development A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json midbrain-hindbrain boundary maturation involved in neural plate development http://purl.obolibrary.org/obo/GO_0022005 GO:0022006 biolink:BiologicalProcess zona limitans intrathalamica formation The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. go-plus.json zli biosynthesis|zli formation http://purl.obolibrary.org/obo/GO_0022006 GO:1901279 biolink:BiologicalProcess D-ribose 5-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate. go-plus.json D-ribose 5-phosphate degradation|D-ribose 5-phosphate catabolism|D-ribose 5-phosphate breakdown http://purl.obolibrary.org/obo/GO_1901279 OBO:GOCHE_52217 biolink:OntologyClass substance with pharmaceutical role go-plus.json http://purl.obolibrary.org/obo/GOCHE_52217 3_STAR GO:1901277 biolink:BiologicalProcess tartrate biosynthetic process The chemical reactions and pathways resulting in the formation of tartrate. go-plus.json tartrate anabolism|tartrate synthesis|tartrate formation|tartrate biosynthesis http://purl.obolibrary.org/obo/GO_1901277 GO:1901278 biolink:BiologicalProcess D-ribose 5-phosphate metabolic process The chemical reactions and pathways involving D-ribose 5-phosphate. go-plus.json D-ribose 5-phosphate metabolism http://purl.obolibrary.org/obo/GO_1901278 GO:1901275 biolink:BiologicalProcess tartrate metabolic process The chemical reactions and pathways involving tartrate. go-plus.json tartrate metabolism http://purl.obolibrary.org/obo/GO_1901275 GO:1901276 biolink:BiologicalProcess tartrate catabolic process The chemical reactions and pathways resulting in the breakdown of tartrate. go-plus.json tartrate degradation|tartrate breakdown|tartrate catabolism http://purl.obolibrary.org/obo/GO_1901276 OBO:GOCHE_52214 biolink:OntologyClass substance with ligand role go-plus.json http://purl.obolibrary.org/obo/GOCHE_52214 3_STAR GO:1901284 biolink:BiologicalProcess 5,6,7,8-tetrahydromethanopterin catabolic process The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin. go-plus.json 5,6,7,8-tetrahydromethanopterin degradation|5,6,7,8-tetrahydromethanopterin breakdown|5,6,7,8-tetrahydromethanopterin catabolism http://purl.obolibrary.org/obo/GO_1901284 GO:1901285 biolink:BiologicalProcess 5,6,7,8-tetrahydromethanopterin biosynthetic process The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin. go-plus.json 5,6,7,8-tetrahydromethanopterin formation|5,6,7,8-tetrahydromethanopterin biosynthesis|5,6,7,8-tetrahydromethanopterin anabolism|5,6,7,8-tetrahydromethanopterin synthesis http://purl.obolibrary.org/obo/GO_1901285 GO:1901282 biolink:BiologicalProcess fructoselysine biosynthetic process The chemical reactions and pathways resulting in the formation of fructoselysine. go-plus.json fructosyllysine anabolism|fructosyllysine biosynthesis|fructosyllysine synthesis|fructosyllysine formation|fructosyllysine biosynthetic process http://purl.obolibrary.org/obo/GO_1901282 GO:1901283 biolink:BiologicalProcess 5,6,7,8-tetrahydromethanopterin metabolic process The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin. go-plus.json 5,6,7,8-tetrahydromethanopterin metabolism http://purl.obolibrary.org/obo/GO_1901283 GO:1901280 biolink:BiologicalProcess D-ribose 5-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate. go-plus.json D-ribose 5-phosphate biosynthesis|D-ribose 5-phosphate anabolism|D-ribose 5-phosphate synthesis|D-ribose 5-phosphate formation http://purl.obolibrary.org/obo/GO_1901280 GO:1901281 biolink:BiologicalProcess fructoselysine catabolic process The chemical reactions and pathways resulting in the breakdown of fructoselysine. go-plus.json fructosyllysine catabolism|fructosyllysine catabolic process|fructosyllysine degradation|fructosyllysine breakdown http://purl.obolibrary.org/obo/GO_1901281 GO:0022007 biolink:BiologicalProcess convergent extension involved in neural plate elongation The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate. go-plus.json http://purl.obolibrary.org/obo/GO_0022007 GO:0022008 biolink:BiologicalProcess neurogenesis Generation of cells within the nervous system. Wikipedia:Neurogenesis go-plus.json neural cell differentiation|nervous system cell generation http://purl.obolibrary.org/obo/GO_0022008 GO:0022009 biolink:BiologicalProcess central nervous system vasculogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0022009 GO:0071058 biolink:CellularComponent alpha3-beta1 integrin-CD151 complex A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151. go-plus.json ITGA3-ITGB1-CD151 complex http://purl.obolibrary.org/obo/GO_0071058 GO:0071059 biolink:CellularComponent alpha6-beta1 integrin-CD151 complex A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151. go-plus.json ITGA6-ITGB1-CD151 complex http://purl.obolibrary.org/obo/GO_0071059 CHEBI:9036 biolink:ChemicalSubstance sarpagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9036 chebi_ph7_3 GO:0071056 biolink:CellularComponent alpha9-beta1 integrin-ADAM15 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15. go-plus.json ITGA9-ITGB1-ADAM15 complex http://purl.obolibrary.org/obo/GO_0071056 NCBITaxon:251221 biolink:OrganismalEntity Gloeobacter violaceus PCC 7421 go-plus.json Gloeobacter violaceus ATCC 29082 http://purl.obolibrary.org/obo/NCBITaxon_251221 GO:0071057 biolink:CellularComponent alphav-beta3 integrin-ADAM15 complex A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15. go-plus.json ITGAV-ITGB3-ADAM15 complex http://purl.obolibrary.org/obo/GO_0071057 CHEBI:9096 biolink:ChemicalSubstance L-selenohomocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9096 CHEBI:75558 biolink:ChemicalSubstance 2-oleoyl-3-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75558 chebi_ph7_3 CHEBI:9093 biolink:ChemicalSubstance selenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9093 GO:0061600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061600 GO:0061601 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061601 GO:0061602 biolink:MolecularActivity molybdenum cofactor cytidylyltransferase activity Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor. RHEA:31335|EC:2.7.7.76 go-plus.json http://purl.obolibrary.org/obo/GO_0061602 GO:0061603 biolink:MolecularActivity molybdenum cofactor guanylyltransferase activity Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor. RHEA:34243|EC:2.7.7.77 go-plus.json http://purl.obolibrary.org/obo/GO_0061603 GO:0061604 biolink:MolecularActivity molybdopterin-synthase sulfurtransferase activity Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase. RHEA:48612|EC:2.8.1.11 go-plus.json http://purl.obolibrary.org/obo/GO_0061604 CHEBI:75550 biolink:ChemicalSubstance 1-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75550 chebi_ph7_3 GO:0061605 biolink:MolecularActivity molybdopterin-synthase adenylyltransferase activity Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP. EC:2.7.7.80|RHEA:43616 go-plus.json http://purl.obolibrary.org/obo/GO_0061605 GO:0061606 biolink:BiologicalProcess N-terminal protein amino acid propionylation The propionylation of the N-terminal amino acid of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0061606 GO:0061607 biolink:MolecularActivity peptide alpha-N-propionyltransferase activity Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein. go-plus.json N-terminal propionyltransferase activity http://purl.obolibrary.org/obo/GO_0061607 GO:0061608 biolink:MolecularActivity nuclear import signal receptor activity Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein. go-plus.json importin activity http://purl.obolibrary.org/obo/GO_0061608 GO:0061609 biolink:MolecularActivity fructose-1-phosphate aldolase activity Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde. Reactome:R-HSA-70342|RHEA:30851|Reactome:R-HSA-5656438 go-plus.json http://purl.obolibrary.org/obo/GO_0061609 CHEBI:75555 biolink:ChemicalSubstance 1-monostearoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75555 chebi_ph7_3 CHEBI:75553 biolink:ChemicalSubstance 3-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75553 chebi_ph7_3 CHEBI:75569 biolink:ChemicalSubstance 3-linoleoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75569 chebi_ph7_3 CHEBI:75568 biolink:ChemicalSubstance 1-monolinolein go-plus.json http://purl.obolibrary.org/obo/CHEBI_75568 chebi_ph7_3 CHEBI:169944 biolink:ChemicalSubstance kaempferol 7-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_169944 CHEBI:169942 biolink:ChemicalSubstance kaempferol 3-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_169942 CHEBI:75561 biolink:ChemicalSubstance 1-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75561 chebi_ph7_3 CHEBI:75562 biolink:ChemicalSubstance 1-monomyristoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75562 chebi_ph7_3 CHEBI:75563 biolink:ChemicalSubstance 3-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75563 chebi_ph7_3 CHEBI:75579 biolink:ChemicalSubstance 1-lauroyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75579 chebi_ph7_3 NCBITaxon:10114 biolink:OrganismalEntity Rattus go-plus.json rat|rats http://purl.obolibrary.org/obo/NCBITaxon_10114 NCBITaxon:10116 biolink:OrganismalEntity Rattus norvegicus go-plus.json rats|rat|Norway rat|brown rat http://purl.obolibrary.org/obo/NCBITaxon_10116 GO:0061620 biolink:BiologicalProcess glycolytic process through glucose-6-phosphate The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP. MetaCyc:GLYCOLYSIS go-plus.json http://purl.obolibrary.org/obo/GO_0061620 GO:0061621 biolink:BiologicalProcess canonical glycolysis The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. Reactome:R-HSA-70171|MetaCyc:PWY66-400|MetaCyc:ANAGLYCOLYSIS-PWY|Wikipedia:Glycolysis go-plus.json http://purl.obolibrary.org/obo/GO_0061621 GO:0061622 biolink:BiologicalProcess glycolytic process through glucose-1-phosphate The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0061622 GO:0061623 biolink:BiologicalProcess glycolytic process from galactose The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0061623 GO:0061624 biolink:BiologicalProcess fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0061624 GO:0061625 biolink:BiologicalProcess glycolytic process through fructose-1-phosphate The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH. go-plus.json http://purl.obolibrary.org/obo/GO_0061625 GO:0061626 biolink:BiologicalProcess pharyngeal arch artery morphogenesis The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. go-plus.json aortic arch artery morphogenesis http://purl.obolibrary.org/obo/GO_0061626 GO:0061627 biolink:MolecularActivity S-methylmethionine-homocysteine S-methyltransferase activity Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+. RHEA:26337|Reactome:R-HSA-5696838 go-plus.json homocysteine methyltransferase activity|S-methylmethionine homocysteine transmethylase activity|homocysteine transmethylase activity|methylmethionine:homocysteine methyltransferase activity http://purl.obolibrary.org/obo/GO_0061627 CHEBI:75573 biolink:ChemicalSubstance 2-oleoyl-3-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75573 chebi_ph7_3 GO:0061628 biolink:MolecularActivity H3K27me3 modified histone binding Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation. go-plus.json H3-K27me3 modified histone binding http://purl.obolibrary.org/obo/GO_0061628 GO:0061629 biolink:MolecularActivity RNA polymerase II-specific DNA-binding transcription factor binding Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. go-plus.json RNA polymerase II activating transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II sequence-specific DNA binding transcription factor binding|RNA polymerase II transcription factor binding|RNA polymerase II sequence-specific DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0061629 CHEBI:75571 biolink:ChemicalSubstance 3-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75571 chebi_ph7_3 CHEBI:9068 biolink:ChemicalSubstance Se-methylselenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_9068 GO:0061610 biolink:BiologicalProcess glycerol to glycerone phosphate metabolic process The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate. go-plus.json glycerol to dihydroxyacetone phosphate metabolic process|glycerol metabolism to DHAP|glycerol metabolism to dihydroxyacetone phosphate|glycerol to DHAP metabolic process|glycerol metabolism to glycerone phosphate http://purl.obolibrary.org/obo/GO_0061610 GO:0061611 biolink:BiologicalProcess mannose to fructose-6-phosphate metabolic process The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate. go-plus.json mannose metabolism to fructose-6-phosphate http://purl.obolibrary.org/obo/GO_0061611 GO:0061612 biolink:BiologicalProcess galactose to glucose-1-phosphate metabolic process The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0061612 GO:0061613 biolink:BiologicalProcess glycolytic process from glycerol The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH. go-plus.json http://purl.obolibrary.org/obo/GO_0061613 GO:0061614 biolink:BiologicalProcess pri-miRNA transcription by RNA polymerase II The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation. go-plus.json pri-miRNA transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0061614 GO:0061615 biolink:BiologicalProcess glycolytic process through fructose-6-phosphate The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH. MetaCyc:PWY-5484 go-plus.json glycolysis through fructose-6-phosphate http://purl.obolibrary.org/obo/GO_0061615 CHEBI:75583 biolink:ChemicalSubstance 1,2-dioleoyl-3-palmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75583 chebi_ph7_3 GO:0061616 biolink:BiologicalProcess glycolytic process from fructose through fructose-6-phosphate The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate. MetaCyc:PWY-5484 go-plus.json glycolysis from fructose through fructose-6-phosphate http://purl.obolibrary.org/obo/GO_0061616 CHEBI:75584 biolink:ChemicalSubstance palmityl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75584 chebi_ph7_3 GO:0061617 biolink:CellularComponent MICOS complex Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60. go-plus.json MitOS complex|MINOS complex|mitochondrial contact site and cristae organizing system|Fcj1 complex http://purl.obolibrary.org/obo/GO_0061617 CHEBI:75582 biolink:ChemicalSubstance 1-myristoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75582 chebi_ph7_3 GO:0061618 biolink:CellularComponent obsolete sublamina densa OBSOLETE. The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0061618 CHEBI:75587 biolink:ChemicalSubstance 2-hydroxypalmityl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75587 chebi_ph7_3 GO:0061619 biolink:BiologicalProcess glycolytic process from mannose through fructose-6-phosphate The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH. go-plus.json http://purl.obolibrary.org/obo/GO_0061619 CHEBI:75585 biolink:ChemicalSubstance 1-palmitoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75585 chebi_ph7_3 CHEBI:75586 biolink:ChemicalSubstance 1,2-hexadecanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75586 chebi_ph7_3 GO:0046000 biolink:BiologicalProcess positive regulation of ecdysteroid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid. go-plus.json up regulation of ecdysteroid secretion|activation of ecdysteroid secretion|stimulation of ecdysteroid secretion|up-regulation of ecdysteroid secretion|upregulation of ecdysteroid secretion http://purl.obolibrary.org/obo/GO_0046000 GO:0046007 biolink:BiologicalProcess negative regulation of activated T cell proliferation Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation. go-plus.json negative regulation of activated T-lymphocyte proliferation|down-regulation of activated T cell proliferation|negative regulation of activated T lymphocyte proliferation|downregulation of activated T cell proliferation|down regulation of activated T cell proliferation|inhibition of activated T cell proliferation|negative regulation of activated T-cell proliferation http://purl.obolibrary.org/obo/GO_0046007 GO:0046008 biolink:BiologicalProcess regulation of female receptivity, post-mating Any process that modulates the receptiveness of a female to male advances subsequent to mating. go-plus.json http://purl.obolibrary.org/obo/GO_0046008 CHEBI:169979 biolink:ChemicalSubstance (+)-trans-isopiperitenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_169979 GO:0046005 biolink:BiologicalProcess positive regulation of circadian sleep/wake cycle, REM sleep Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep. go-plus.json up-regulation of circadian sleep/wake cycle, REM sleep|upregulation of circadian sleep/wake cycle, REM sleep|up regulation of circadian sleep/wake cycle, REM sleep|activation of circadian sleep/wake cycle, REM sleep|stimulation of circadian sleep/wake cycle, REM sleep|positive regulation of REM sleep http://purl.obolibrary.org/obo/GO_0046005 GO:0046006 biolink:BiologicalProcess regulation of activated T cell proliferation Any process that modulates the frequency, rate or extent of activated T cell proliferation. go-plus.json regulation of activated T-cell proliferation|regulation of activated T-lymphocyte proliferation|regulation of activated T lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046006 GO:0046003 biolink:BiologicalProcess negative regulation of syncytial blastoderm mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle. go-plus.json negative regulation of syncytial blastoderm cell cycle progression|down regulation of progression through syncytial blastoderm mitotic cell cycle|negative regulation of progression through syncytial blastoderm mitotic cell cycle|downregulation of progression through syncytial blastoderm mitotic cell cycle|down-regulation of progression through syncytial blastoderm mitotic cell cycle|inhibition of progression through syncytial blastoderm mitotic cell cycle http://purl.obolibrary.org/obo/GO_0046003 GO:0046004 biolink:BiologicalProcess positive regulation of syncytial blastoderm mitotic cell cycle Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle. go-plus.json upregulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of progression through syncytial blastoderm mitotic cell cycle|up regulation of progression through syncytial blastoderm mitotic cell cycle|activation of progression through syncytial blastoderm mitotic cell cycle|stimulation of progression through syncytial blastoderm mitotic cell cycle|up-regulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of syncytial blastoderm cell cycle progression http://purl.obolibrary.org/obo/GO_0046004 GO:0046001 biolink:BiologicalProcess negative regulation of preblastoderm mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle. go-plus.json downregulation of progression through preblastoderm mitotic cell cycle|down regulation of progression through preblastoderm mitotic cell cycle|inhibition of progression through preblastoderm mitotic cell cycle|negative regulation of progression through preblastoderm mitotic cell cycle|down-regulation of progression through preblastoderm mitotic cell cycle|negative regulation of preblastoderm mitotic cell cycle progression http://purl.obolibrary.org/obo/GO_0046001 GO:0046002 biolink:BiologicalProcess positive regulation of preblastoderm mitotic cell cycle Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle. go-plus.json positive regulation of preblastoderm mitotic cell cycle progression|upregulation of progression through preblastoderm mitotic cell cycle|stimulation of progression through preblastoderm mitotic cell cycle|positive regulation of progression through preblastoderm mitotic cell cycle|up-regulation of progression through preblastoderm mitotic cell cycle|activation of progression through preblastoderm mitotic cell cycle|up regulation of progression through preblastoderm mitotic cell cycle http://purl.obolibrary.org/obo/GO_0046002 GO:0061640 biolink:BiologicalProcess cytoskeleton-dependent cytokinesis A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0061640 GO:0061641 biolink:BiologicalProcess CENP-A containing chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin. go-plus.json centromeric chromatin organization http://purl.obolibrary.org/obo/GO_0061641 GO:0061642 biolink:BiologicalProcess chemoattraction of axon The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal. go-plus.json http://purl.obolibrary.org/obo/GO_0061642 GO:0061643 biolink:BiologicalProcess chemorepulsion of axon The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. go-plus.json http://purl.obolibrary.org/obo/GO_0061643 GO:0061644 biolink:BiologicalProcess protein localization to CENP-A containing chromatin Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0061644 CHEBI:75590 biolink:ChemicalSubstance 1-stearoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75590 chebi_ph7_3 GO:0061645 biolink:CellularComponent endocytic patch The part of the cell cortex consisting of an aggregation of proteins that will give rise to an endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0061645 CHEBI:75591 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_75591 GO:0061646 biolink:BiologicalProcess positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0061646 GO:0046009 biolink:BiologicalProcess positive regulation of female receptivity, post-mating Any process that increases the receptiveness of a female to male advances subsequent to mating. go-plus.json up regulation of female receptivity, post-mating|activation of female receptivity, post-mating|stimulation of female receptivity, post-mating|up-regulation of female receptivity, post-mating|upregulation of female receptivity, post-mating http://purl.obolibrary.org/obo/GO_0046009 GO:0061647 biolink:BiologicalProcess histone H3-K9 modification The modification of histone H3 at a lysine in position 9 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0061647 GO:0061648 biolink:BiologicalProcess tooth replacement The process whose specific outcome is the replacement of an existing tooth with another tooth. go-plus.json http://purl.obolibrary.org/obo/GO_0061648 GO:0061649 biolink:MolecularActivity ubiquitin modification-dependent histone binding Binding to a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json ubiquitinated histone binding http://purl.obolibrary.org/obo/GO_0061649 CHEBI:75592 biolink:ChemicalSubstance L-cycloserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75592 CHEBI:75596 biolink:ChemicalSubstance EC 5.* (isomerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_75596 GO:0046010 biolink:BiologicalProcess positive regulation of circadian sleep/wake cycle, non-REM sleep Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep. go-plus.json activation of circadian sleep/wake cycle, non-REM sleep|stimulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of non-REM sleep|up-regulation of circadian sleep/wake cycle, non-REM sleep|upregulation of circadian sleep/wake cycle, non-REM sleep|up regulation of circadian sleep/wake cycle, non-REM sleep http://purl.obolibrary.org/obo/GO_0046010 GO:0046011 biolink:BiologicalProcess regulation of oskar mRNA translation Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0046011 GO:0046018 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase I promoter during mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle. go-plus.json up-regulation of transcription from RNA polymerase I promoter during mitosis|mitotic activation of transcription from Pol I promoter|positive regulation of transcription from Pol I promoter during mitosis|upregulation of transcription from RNA polymerase I promoter during mitosis|up regulation of transcription from RNA polymerase I promoter during mitosis|activation of transcription from RNA polymerase I promoter during mitosis|stimulation of transcription from RNA polymerase I promoter during mitosis|positive regulation of transcription from RNA polymerase I promoter, mitotic http://purl.obolibrary.org/obo/GO_0046018 GO:0046019 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter by pheromones Any process involving pheromones that modulates the frequency, rate or extent or transcription from an RNA polymerase II promoter. go-plus.json regulation of transcription from Pol II promoter by pheromones http://purl.obolibrary.org/obo/GO_0046019 GO:0046016 biolink:BiologicalProcess positive regulation of transcription by glucose Any process involving glucose that activates or increases the rate of transcription. go-plus.json upregulation of transcription by glucose|stimulation of transcription by glucose|up-regulation of transcription by glucose|activation of transcription by glucose|up regulation of transcription by glucose http://purl.obolibrary.org/obo/GO_0046016 GO:0046017 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase I promoter during mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle. go-plus.json regulation of transcription from Pol I promoter during mitosis|regulation of transcription from RNA polymerase I promoter during mitosis|mitotic regulation of transcription from Pol I promoter http://purl.obolibrary.org/obo/GO_0046017 GO:0046014 biolink:BiologicalProcess negative regulation of T cell homeostatic proliferation Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation. go-plus.json negative regulation of T-lymphocyte homeostatic proliferation|down-regulation of T cell homeostatic proliferation|negative regulation of T lymphocyte homeostatic proliferation|downregulation of T cell homeostatic proliferation|negative regulation of resting T cell proliferation|down regulation of T cell homeostatic proliferation|inhibition of T cell homeostatic proliferation|negative regulation of T-cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046014 GO:0046015 biolink:BiologicalProcess regulation of transcription by glucose Any process involving glucose that modulates the frequency, rate or extent or transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0046015 GO:0046012 biolink:BiologicalProcess positive regulation of oskar mRNA translation Any process that activates or increases the frequency, rate or extent of oskar mRNA translation. go-plus.json upregulation of oskar mRNA translation|stimulation of oskar mRNA translation|activation of oskar mRNA translation|up-regulation of oskar mRNA translation|up regulation of oskar mRNA translation http://purl.obolibrary.org/obo/GO_0046012 GO:0046013 biolink:BiologicalProcess regulation of T cell homeostatic proliferation Any process that modulates the frequency, rate or extent of resting T cell proliferation. go-plus.json regulation of resting T cell proliferation|regulation of T-cell homeostatic proliferation|regulation of T-lymphocyte homeostatic proliferation|regulation of T lymphocyte homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046013 GO:0061630 biolink:MolecularActivity ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. Reactome:R-HSA-8939706|Reactome:R-HSA-6781867|Reactome:R-HSA-5654679|Reactome:R-HSA-9009308|Reactome:R-HSA-5687081|Reactome:R-HSA-5654677|Reactome:R-HSA-8866546|Reactome:R-HSA-201445|Reactome:R-HSA-8956684|Reactome:R-HSA-5690827|Reactome:R-HSA-8848829|Reactome:R-HSA-8877003|Reactome:R-HSA-3322429|Reactome:R-HSA-6782943|Reactome:R-HSA-936475|Reactome:R-HSA-9009403|Reactome:R-HSA-8875431|Reactome:R-HSA-5246693|Reactome:R-HSA-8939335|Reactome:R-HSA-1504190|Reactome:R-HSA-5654672|Reactome:R-HSA-8876258|Reactome:R-HSA-9011300|Reactome:R-HSA-990526|Reactome:R-HSA-8952382|Reactome:R-HSA-9686969|Reactome:R-HSA-8854628|Reactome:R-HSA-5654684|Reactome:R-HSA-8854051|Reactome:R-HSA-6804253|Reactome:R-HSA-6804879|Reactome:R-HSA-1225956|Reactome:R-HSA-934604|Reactome:R-HSA-3640861|Reactome:R-HSA-69015|Reactome:R-HSA-68946|Reactome:R-HSA-6804942|Reactome:R-HSA-8875183|Reactome:R-HSA-8938773|Reactome:R-HSA-5635864|Reactome:R-HSA-9008076|Reactome:R-HSA-5689111|Reactome:R-HSA-8943080|Reactome:R-HSA-8866856|Reactome:R-HSA-6804724|Reactome:R-HSA-5610737|Reactome:R-HSA-5684071|Reactome:R-HSA-6785361|Reactome:R-HSA-8943003|Reactome:R-HSA-6807106|Reactome:R-HSA-5635856|Reactome:R-HSA-5658424|Reactome:R-HSA-8956026|Reactome:R-HSA-8943040|Reactome:R-HSA-8948775|Reactome:R-HSA-6790487|Reactome:R-HSA-8953946|Reactome:R-HSA-6798373|Reactome:R-HSA-4641129|Reactome:R-HSA-5632648|Reactome:R-HSA-4641253|Reactome:R-HSA-9706354|Reactome:R-HSA-8952419|Reactome:R-HSA-6804441|Reactome:R-HSA-8948832|Reactome:R-HSA-8854041|Reactome:R-HSA-5682858|Reactome:R-HSA-9686920|Reactome:R-HSA-9604629|Reactome:R-HSA-4641246|Reactome:R-HSA-9706356|Reactome:R-HSA-4608852|Reactome:R-HSA-9021523|Reactome:R-HSA-9033485|Reactome:R-HSA-8867288|Reactome:R-HSA-8942101|Reactome:R-HSA-6807134|Reactome:R-HSA-4641159|Reactome:R-HSA-8851011|Reactome:R-HSA-936462|Reactome:R-HSA-8938815|Reactome:R-HSA-5674022|Reactome:R-HSA-9008479 go-plus.json E3 involved in endoplasmic reticulum-associated degradation|ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition|ubiquitin protein ligase activity involved in chloroplast disassembly|APC-Cdc20 complex activity|APC-fizzy related complex activity|ER-associated E3 ligase|ubiquitin ligase activity|ubiquitin protein ligase activity involved in ERAD pathway|ubiquitin protein ligase activity involved in ER-associated degradation pathway|protein ubiquitination activity|ubiquitin ligase activity involved in ER-associated degradation pathway|E3 http://purl.obolibrary.org/obo/GO_0061630 GO:0061631 biolink:MolecularActivity ubiquitin conjugating enzyme activity Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. EC:2.3.2.23 go-plus.json HECT E3|E2 http://purl.obolibrary.org/obo/GO_0061631 GO:0061632 biolink:MolecularActivity RNA lariat debranching enzyme activator activity Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0061632 GO:0061633 biolink:BiologicalProcess transport-coupled glycolytic process through glucose-6-phosphate The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_0061633 GO:0061634 biolink:MolecularActivity alpha-D-xyloside xylohydrolase Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose. EC:3.2.1.177 go-plus.json alpha-xylosidase http://purl.obolibrary.org/obo/GO_0061634 GO:0061635 biolink:BiologicalProcess regulation of protein complex stability Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly. go-plus.json http://purl.obolibrary.org/obo/GO_0061635 GO:0061636 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061636 GO:0061637 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061637 GO:0061638 biolink:CellularComponent CENP-A containing chromatin The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment. go-plus.json centromeric core region chromatin|chromatin containing CENP-A|nuclear CENP-A containing chromatin|centromeric core domain chromatin http://purl.obolibrary.org/obo/GO_0061638 GO:0061639 biolink:BiologicalProcess Cdv-dependent cytokinesis A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells. go-plus.json http://purl.obolibrary.org/obo/GO_0061639 GO:0046021 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter during mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle. go-plus.json regulation of transcription from RNA polymerase II promoter during mitosis|regulation of transcription from Pol II promoter, mitotic|mitotic regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0046021 GO:0046022 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle. go-plus.json up regulation of transcription from RNA polymerase II promoter during mitosis|positive regulation of transcription from RNA polymerase II promoter, mitotic|mitotic activation of transcription from Pol II promoter|upregulation of transcription from RNA polymerase II promoter during mitosis|positive regulation of transcription from Pol II promoter during mitosis|stimulation of transcription from RNA polymerase II promoter during mitosis|up-regulation of transcription from RNA polymerase II promoter during mitosis|activation of transcription from RNA polymerase II promoter during mitosis http://purl.obolibrary.org/obo/GO_0046022 GO:0046020 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter by pheromones Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. go-plus.json down regulation of transcription from RNA polymerase II promoter by pheromones|downregulation of transcription from RNA polymerase II promoter by pheromones|down-regulation of transcription from RNA polymerase II promoter by pheromones|inhibition of transcription from RNA polymerase II promoter by pheromones|negative regulation of transcription from Pol II promoter by pheromones http://purl.obolibrary.org/obo/GO_0046020 GO:0046029 biolink:MolecularActivity mannitol dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH. RHEA:15029|KEGG_REACTION:R07135|MetaCyc:1.1.1.255-RXN|EC:1.1.1.255 go-plus.json NAD-dependent mannitol dehydrogenase activity|mannitol:NAD+ 1-oxidoreductase activity|MTD activity http://purl.obolibrary.org/obo/GO_0046029 GO:0046027 biolink:MolecularActivity phospholipid:diacylglycerol acyltransferase activity Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol. MetaCyc:2.3.1.158-RXN|RHEA:14057|EC:2.3.1.158 go-plus.json phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity|PDAT activity http://purl.obolibrary.org/obo/GO_0046027 GO:0046028 biolink:MolecularActivity electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II. go-plus.json plastocyanin http://purl.obolibrary.org/obo/GO_0046028 GO:0046025 biolink:MolecularActivity precorrin-6Y C5,15-methyltransferase (decarboxylating) activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2. RHEA:17477|MetaCyc:2.1.1.132-RXN|EC:2.1.1.132 go-plus.json precorrin-6Y methylase activity|S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)|precorrin-6 methyltransferase activity http://purl.obolibrary.org/obo/GO_0046025 GO:0046026 biolink:MolecularActivity precorrin-4 C11-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5. RHEA:22012|MetaCyc:2.1.1.133-RXN|EC:2.1.1.133 go-plus.json CobM|S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity http://purl.obolibrary.org/obo/GO_0046026 GO:0061660 biolink:MolecularActivity Atg12 ligase activity Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061660 GO:0046023 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase III promoter during mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle. go-plus.json mitotic regulation of transcription from Pol III promoter|regulation of transcription from RNA polymerase III promoter during mitosis|regulation of transcription from Pol III promoter, mitotic http://purl.obolibrary.org/obo/GO_0046023 GO:0046024 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase III promoter during mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III that occurs during the mitotic cell cycle. go-plus.json up regulation of transcription from RNA polymerase III promoter during mitosis|activation of transcription from RNA polymerase III promoter during mitosis|stimulation of transcription from RNA polymerase III promoter during mitosis|positive regulation of transcription from RNA polymerase III promoter, mitotic|up-regulation of transcription from RNA polymerase III promoter during mitosis|mitotic activation of transcription from Pol III promoter|positive regulation of transcription from Pol III promoter during mitosis|upregulation of transcription from RNA polymerase III promoter during mitosis http://purl.obolibrary.org/obo/GO_0046024 GO:0061661 biolink:MolecularActivity FAT10 ligase activity Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061661 GO:0061662 biolink:MolecularActivity ISG15 ligase activity Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061662 GO:0061663 biolink:MolecularActivity NEDD8 ligase activity Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061663 GO:0061664 biolink:MolecularActivity Pup ligase activity Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061664 GO:0061665 biolink:MolecularActivity SUMO ligase activity Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061665 GO:0061666 biolink:MolecularActivity UFM1 ligase activity Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061666 GO:0061667 biolink:MolecularActivity URM1 ligase activity Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate. go-plus.json E3 http://purl.obolibrary.org/obo/GO_0061667 GO:0061668 biolink:BiologicalProcess mitochondrial ribosome assembly The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0061668 GO:0061669 biolink:BiologicalProcess spontaneous neurotransmitter secretion Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential. go-plus.json stimulus-independent neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0061669 GO:0046032 biolink:BiologicalProcess ADP catabolic process The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate. go-plus.json ADP degradation|ADP breakdown|ADP catabolism http://purl.obolibrary.org/obo/GO_0046032 GO:0046033 biolink:BiologicalProcess AMP metabolic process The chemical reactions and pathways involving AMP, adenosine monophosphate. go-plus.json adenylate forming enzyme activity|AMP metabolism http://purl.obolibrary.org/obo/GO_0046033 GO:0046030 biolink:MolecularActivity inositol trisphosphate phosphatase activity Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate. go-plus.json IP3 phosphatase activity|IP(3) phosphatase activity|inositol-1,4,5-trisphosphate phosphatase http://purl.obolibrary.org/obo/GO_0046030 GO:0046031 biolink:BiologicalProcess ADP metabolic process The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate. go-plus.json ADP metabolism http://purl.obolibrary.org/obo/GO_0046031 GO:0046038 biolink:BiologicalProcess GMP catabolic process The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate. go-plus.json GMP degradation|GMP breakdown|GMP catabolism http://purl.obolibrary.org/obo/GO_0046038 GO:0046039 biolink:BiologicalProcess GTP metabolic process The chemical reactions and pathways involving GTP, guanosine triphosphate. go-plus.json GTP metabolism http://purl.obolibrary.org/obo/GO_0046039 GO:0046036 biolink:BiologicalProcess CTP metabolic process The chemical reactions and pathways involving CTP, cytidine triphosphate. go-plus.json CTP metabolism|CTP deamination http://purl.obolibrary.org/obo/GO_0046036 GO:0046037 biolink:BiologicalProcess GMP metabolic process The chemical reactions and pathways involving GMP, guanosine monophosphate. go-plus.json GMP metabolism http://purl.obolibrary.org/obo/GO_0046037 GO:0046034 biolink:BiologicalProcess ATP metabolic process The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. go-plus.json ATP metabolism http://purl.obolibrary.org/obo/GO_0046034 GO:0046035 biolink:BiologicalProcess CMP metabolic process The chemical reactions and pathways involving CMP, cytidine monophosphate. go-plus.json CMP metabolism http://purl.obolibrary.org/obo/GO_0046035 GO:0061650 biolink:MolecularActivity ubiquitin-like protein conjugating enzyme activity Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue. go-plus.json E2|small conjugating protein conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0061650 GO:0061651 biolink:MolecularActivity Atg12 conjugating enzyme activity Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061651 GO:0061652 biolink:MolecularActivity FAT10 conjugating enzyme activity Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061652 GO:0061653 biolink:MolecularActivity ISG15 conjugating enzyme activity Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061653 GO:0061654 biolink:MolecularActivity NEDD8 conjugating enzyme activity Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061654 GO:0061655 biolink:MolecularActivity Pup conjugating enzyme activity Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061655 GO:0061656 biolink:MolecularActivity SUMO conjugating enzyme activity Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061656 GO:0061657 biolink:MolecularActivity UFM1 conjugating enzyme activity Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061657 GO:0061658 biolink:MolecularActivity URM1 conjugating enzyme activity Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue. go-plus.json E2 http://purl.obolibrary.org/obo/GO_0061658 GO:0061659 biolink:MolecularActivity ubiquitin-like protein ligase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate. go-plus.json small conjugating protein ligase activity|E3 http://purl.obolibrary.org/obo/GO_0061659 GO:1905130 biolink:BiologicalProcess carcinine import across plasma membrane The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1905130 GO:1905131 biolink:MolecularActivity carcinine transmembrane transporter activity Enables the transfer of carcinine from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1905131 GO:1905132 biolink:BiologicalProcess regulation of meiotic chromosome separation Any process that modulates the frequency, rate or extent of meiotic chromosome separation. go-plus.json regulation of chromosome separation during meiosis|regulation of meiotic chromosome resolution http://purl.obolibrary.org/obo/GO_1905132 GO:1905133 biolink:BiologicalProcess negative regulation of meiotic chromosome separation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation. go-plus.json down-regulation of meiotic chromosome resolution|negative regulation of meiotic chromosome resolution|down regulation of chromosome separation during meiosis|inhibition of chromosome separation during meiosis|down-regulation of meiotic chromosome separation|inhibition of meiotic chromosome resolution|inhibition of meiotic chromosome separation|down regulation of meiotic chromosome resolution|negative regulation of chromosome separation during meiosis|down-regulation of chromosome separation during meiosis|downregulation of meiotic chromosome resolution|down regulation of meiotic chromosome separation|downregulation of meiotic chromosome separation|downregulation of chromosome separation during meiosis http://purl.obolibrary.org/obo/GO_1905133 GO:1905134 biolink:BiologicalProcess positive regulation of meiotic chromosome separation Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation. go-plus.json up regulation of meiotic chromosome separation|activation of meiotic chromosome separation|upregulation of chromosome separation during meiosis|up-regulation of meiotic chromosome resolution|up-regulation of meiotic chromosome separation|up-regulation of chromosome separation during meiosis|activation of chromosome separation during meiosis|upregulation of meiotic chromosome resolution|upregulation of meiotic chromosome separation|positive regulation of chromosome separation during meiosis|up regulation of meiotic chromosome resolution|positive regulation of meiotic chromosome resolution|up regulation of chromosome separation during meiosis|activation of meiotic chromosome resolution http://purl.obolibrary.org/obo/GO_1905134 GO:1905135 biolink:BiologicalProcess biotin import across plasma membrane The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json biotin import into cell|biotin import http://purl.obolibrary.org/obo/GO_1905135 GO:1905125 biolink:BiologicalProcess positive regulation of glucosylceramidase activity Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity. go-plus.json upregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|positive regulation of beta-glucocerebrosidase activity|upregulation of glucosylcerebrosidase activity|upregulation of glucosylsphingosine beta-glucosidase activity|up-regulation of glucocerebrosidase activity|up regulation of beta-glucocerebrosidase activity|up regulation of glucosylsphingosine beta-D-glucosidase activity|activation of glucosylsphingosine beta-D-glucosidase activity|upregulation of acid beta-glucosidase activity|activation of GlcCer-beta-glucosidase activity|up-regulation of GlcCer-beta-glucosidase activity|positive regulation of glucosylsphingosine beta-D-glucosidase activity|up-regulation of glucosphingosine glucosylhydrolase activity|positive regulation of GCase activity|upregulation of ceramide glucosidase activity|up-regulation of psychosine hydrolase activity|up regulation of glucosylceramidase activity|up-regulation of beta-glucosylceramidase activity|activation of beta-glucosylceramidase activity|positive regulation of beta-D-glucocerebrosidase activity|activation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|activation of glucosylceramidase activity|up-regulation of glucosylcerebrosidase activity|activation of glucosylcerebrosidase activity|up regulation of beta-D-glucocerebrosidase activity|upregulation of glucocerebrosidase activity|up regulation of glucosylsphingosine beta-glucosidase activity|upregulation of beta-glucocerebrosidase activity|activation of glucosylsphingosine beta-glucosidase activity|up-regulation of acid beta-glucosidase activity|activation of acid beta-glucosidase activity|positive regulation of glucosylsphingosine beta-glucosidase activity|upregulation of glucosphingosine glucosylhydrolase activity|up-regulation of glucosylsphingosine beta-D-glucosidase activity|positive regulation of GlcCer-beta-glucosidase activity|upregulation of psychosine hydrolase activity|up regulation of ceramide glucosidase activity|up regulation of GlcCer-beta-glucosidase activity|activation of ceramide glucosidase activity|positive regulation of beta-glucosylceramidase activity|positive regulation of ceramide glucosidase activity|positive regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of beta-glucosylceramidase activity|upregulation of beta-D-glucocerebrosidase activity|activation of beta-glucocerebrosidase activity|positive regulation of glucosylcerebrosidase activity|up-regulation of glucosylceramidase activity|up regulation of glucocerebrosidase activity|up-regulation of beta-glucocerebrosidase activity|activation of glucocerebrosidase activity|up regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of glucosylcerebrosidase activity|positive regulation of acid beta-glucosidase activity|positive regulation of glucocerebrosidase activity|up-regulation of glucosylsphingosine beta-glucosidase activity|upregulation of glucosylsphingosine beta-D-glucosidase activity|up regulation of glucosphingosine glucosylhydrolase activity|activation of glucosphingosine glucosylhydrolase activity|up regulation of acid beta-glucosidase activity|up regulation of psychosine hydrolase activity|positive regulation of glucosphingosine glucosylhydrolase activity|upregulation of GlcCer-beta-glucosidase activity|activation of psychosine hydrolase activity|positive regulation of psychosine hydrolase activity|up-regulation of ceramide glucosidase activity|activation of beta-D-glucocerebrosidase activity|up-regulation of beta-D-glucocerebrosidase activity|upregulation of glucosylceramidase activity|upregulation of beta-glucosylceramidase activity http://purl.obolibrary.org/obo/GO_1905125 GO:0090327 biolink:BiologicalProcess negative regulation of locomotion involved in locomotory behavior Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. go-plus.json http://purl.obolibrary.org/obo/GO_0090327 GO:1905126 biolink:BiologicalProcess regulation of axo-dendritic protein transport Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. go-plus.json regulation of axonal protein transport http://purl.obolibrary.org/obo/GO_1905126 GO:0090328 biolink:BiologicalProcess regulation of olfactory learning Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. go-plus.json http://purl.obolibrary.org/obo/GO_0090328 GO:1905127 biolink:BiologicalProcess negative regulation of axo-dendritic protein transport Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. go-plus.json down-regulation of axo-dendritic protein transport|inhibition of axo-dendritic protein transport|down-regulation of axonal protein transport|negative regulation of axonal protein transport|downregulation of axonal protein transport|down regulation of axo-dendritic protein transport|down regulation of axonal protein transport|downregulation of axo-dendritic protein transport|inhibition of axonal protein transport http://purl.obolibrary.org/obo/GO_1905127 GO:0090325 biolink:BiologicalProcess regulation of locomotion involved in locomotory behavior Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. go-plus.json http://purl.obolibrary.org/obo/GO_0090325 GO:1905128 biolink:BiologicalProcess positive regulation of axo-dendritic protein transport Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. go-plus.json up-regulation of axonal protein transport|up-regulation of axo-dendritic protein transport|activation of axonal protein transport|positive regulation of axonal protein transport|up regulation of axonal protein transport|upregulation of axo-dendritic protein transport|upregulation of axonal protein transport|up regulation of axo-dendritic protein transport|activation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_1905128 GO:0090326 biolink:BiologicalProcess positive regulation of locomotion involved in locomotory behavior Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. go-plus.json http://purl.obolibrary.org/obo/GO_0090326 GO:1905129 biolink:BiologicalProcess endocannabinoid signaling pathway involved in trans-synaptic signaling Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid. go-plus.json endocannabinoid signalling pathway involved in trans-synaptic signaling by endocannabinoid http://purl.obolibrary.org/obo/GO_1905129 GO:0090329 biolink:BiologicalProcess regulation of DNA-dependent DNA replication Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. go-plus.json http://purl.obolibrary.org/obo/GO_0090329 GO:0090320 biolink:BiologicalProcess regulation of chylomicron remnant clearance Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0090320 GO:0090323 biolink:BiologicalProcess prostaglandin secretion involved in immune response The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring. go-plus.json http://purl.obolibrary.org/obo/GO_0090323 gocheck_do_not_annotate GO:0090324 biolink:BiologicalProcess negative regulation of oxidative phosphorylation Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090324 GO:0090321 biolink:BiologicalProcess positive regulation of chylomicron remnant clearance Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0090321 GO:0090322 biolink:BiologicalProcess regulation of superoxide metabolic process Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. go-plus.json regulation of superoxide metabolism http://purl.obolibrary.org/obo/GO_0090322 GO:1905140 biolink:BiologicalProcess regulation of apical ectodermal ridge formation Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. go-plus.json regulation of AER formation|regulation of apical epidermal ridge formation|regulation of crista ectodermalis apicalis formation http://purl.obolibrary.org/obo/GO_1905140 GO:1905141 biolink:BiologicalProcess negative regulation of apical ectodermal ridge formation Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. go-plus.json downregulation of apical ectodermal ridge formation|down-regulation of apical epidermal ridge formation|negative regulation of apical epidermal ridge formation|inhibition of crista ectodermalis apicalis formation|inhibition of AER formation|downregulation of apical epidermal ridge formation|down-regulation of apical ectodermal ridge formation|down regulation of AER formation|down regulation of apical epidermal ridge formation|downregulation of AER formation|negative regulation of crista ectodermalis apicalis formation|down-regulation of crista ectodermalis apicalis formation|inhibition of apical epidermal ridge formation|inhibition of apical ectodermal ridge formation|down-regulation of AER formation|negative regulation of AER formation|downregulation of crista ectodermalis apicalis formation|down regulation of apical ectodermal ridge formation|down regulation of crista ectodermalis apicalis formation http://purl.obolibrary.org/obo/GO_1905141 GO:1905142 biolink:BiologicalProcess positive regulation of apical ectodermal ridge formation Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. go-plus.json up regulation of apical ectodermal ridge formation|positive regulation of apical epidermal ridge formation|upregulation of AER formation|up regulation of apical epidermal ridge formation|up-regulation of crista ectodermalis apicalis formation|upregulation of apical epidermal ridge formation|up regulation of AER formation|up-regulation of apical ectodermal ridge formation|positive regulation of AER formation|positive regulation of crista ectodermalis apicalis formation|up regulation of crista ectodermalis apicalis formation|activation of AER formation|upregulation of apical ectodermal ridge formation|up-regulation of apical epidermal ridge formation|up-regulation of AER formation|upregulation of crista ectodermalis apicalis formation http://purl.obolibrary.org/obo/GO_1905142 GO:1905143 biolink:BiologicalProcess eukaryotic translation initiation factor 2 complex assembly The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex. go-plus.json eukaryotic translation initiation factor 2 complex formation|eIF2 formation|eIF-2 assembly|eIF-2 formation|eIF2 assembly http://purl.obolibrary.org/obo/GO_1905143 GO:1905144 biolink:BiologicalProcess response to acetylcholine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905144 GO:1905145 biolink:BiologicalProcess cellular response to acetylcholine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905145 GO:1905146 biolink:BiologicalProcess lysosomal protein catabolic process Any cellular protein catabolic process that takes place in a lysosome. go-plus.json cellular protein catabolic process in lysosome|lysosomal proteolysis|cellular protein degradation in lysosome|proteolysis within lysosome|cellular protein breakdown in lysosome|lysosomal protein degradation|cellular protein catabolism in lysosome|lysosomal protein catabolism http://purl.obolibrary.org/obo/GO_1905146 GO:0090338 biolink:BiologicalProcess positive regulation of formin-nucleated actin cable assembly Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. go-plus.json http://purl.obolibrary.org/obo/GO_0090338 GO:1905136 biolink:BiologicalProcess dethiobiotin import across plasma membrane The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json dethiobiotin import|dethiobiotin import into cell http://purl.obolibrary.org/obo/GO_1905136 CHEBI:5337 biolink:ChemicalSubstance (1E,4E)-germacrene B go-plus.json http://purl.obolibrary.org/obo/CHEBI_5337 chebi_ph7_3 GO:1905137 biolink:BiologicalProcess regulation of viral DNA genome packaging via site-specific sequence recognition Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition. go-plus.json http://purl.obolibrary.org/obo/GO_1905137 GO:0090339 biolink:BiologicalProcess negative regulation of formin-nucleated actin cable assembly Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. go-plus.json http://purl.obolibrary.org/obo/GO_0090339 GO:1905138 biolink:BiologicalProcess positive regulation of viral DNA genome packaging via site-specific sequence recognition Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition. go-plus.json up regulation of viral DNA genome packaging via site-specific sequence recognition|activation of viral DNA genome packaging via site-specific sequence recognition|up-regulation of viral DNA genome packaging via site-specific sequence recognition|upregulation of viral DNA genome packaging via site-specific sequence recognition http://purl.obolibrary.org/obo/GO_1905138 GO:0090336 biolink:BiologicalProcess positive regulation of brown fat cell differentiation Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. go-plus.json http://purl.obolibrary.org/obo/GO_0090336 GO:1905139 biolink:BiologicalProcess apical ectodermal ridge formation The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json crista ectodermalis apicalis formation|AER formation|apical epidermal ridge formation http://purl.obolibrary.org/obo/GO_1905139 GO:0090337 biolink:BiologicalProcess regulation of formin-nucleated actin cable assembly Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. go-plus.json http://purl.obolibrary.org/obo/GO_0090337 GO:0090330 biolink:BiologicalProcess regulation of platelet aggregation Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0090330 GO:0090331 biolink:BiologicalProcess negative regulation of platelet aggregation Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. go-plus.json platelet disaggregation http://purl.obolibrary.org/obo/GO_0090331 GO:0090334 biolink:BiologicalProcess regulation of cell wall (1->3)-beta-D-glucan biosynthetic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. go-plus.json regulation of cell wall 1,3-beta-D-glucan biosynthetic process|regulation of cell wall 1,3-beta-glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0090334 GO:0090335 biolink:BiologicalProcess regulation of brown fat cell differentiation Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. go-plus.json http://purl.obolibrary.org/obo/GO_0090335 GO:0090332 biolink:BiologicalProcess stomatal closure The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0090332 GO:0090333 biolink:BiologicalProcess regulation of stomatal closure Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0090333 GO:1905150 biolink:BiologicalProcess regulation of voltage-gated sodium channel activity Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity. go-plus.json regulation of voltage gated sodium channel activity|regulation of voltage-dependent sodium channel activity|regulation of voltage-sensitive sodium channel|regulation of voltage-gated sodium ion channel activity http://purl.obolibrary.org/obo/GO_1905150 GO:1905151 biolink:BiologicalProcess negative regulation of voltage-gated sodium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity. go-plus.json downregulation of voltage-gated sodium ion channel activity|down-regulation of voltage-gated sodium channel activity|inhibition of voltage-dependent sodium channel activity|down regulation of voltage gated sodium channel activity|inhibition of voltage-gated sodium channel activity|negative regulation of voltage-gated sodium ion channel activity|down-regulation of voltage-gated sodium ion channel activity|downregulation of voltage gated sodium channel activity|negative regulation of voltage-sensitive sodium channel|down-regulation of voltage-sensitive sodium channel|down regulation of voltage-dependent sodium channel activity|inhibition of voltage-gated sodium ion channel activity|downregulation of voltage-dependent sodium channel activity|down regulation of voltage-gated sodium channel activity|negative regulation of voltage gated sodium channel activity|down-regulation of voltage gated sodium channel activity|downregulation of voltage-sensitive sodium channel|downregulation of voltage-gated sodium channel activity|down regulation of voltage-sensitive sodium channel|down-regulation of voltage-dependent sodium channel activity|negative regulation of voltage-dependent sodium channel activity|inhibition of voltage gated sodium channel activity|down regulation of voltage-gated sodium ion channel activity|inhibition of voltage-sensitive sodium channel http://purl.obolibrary.org/obo/GO_1905151 GO:1905152 biolink:BiologicalProcess positive regulation of voltage-gated sodium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity. go-plus.json up-regulation of voltage-dependent sodium channel activity|up regulation of voltage-gated sodium ion channel activity|upregulation of voltage gated sodium channel activity|activation of voltage-gated sodium ion channel activity|positive regulation of voltage-gated sodium ion channel activity|activation of voltage-sensitive sodium channel|up-regulation of voltage-sensitive sodium channel|up-regulation of voltage-gated sodium channel activity|upregulation of voltage-dependent sodium channel activity|up regulation of voltage gated sodium channel activity|activation of voltage gated sodium channel activity|positive regulation of voltage gated sodium channel activity|up-regulation of voltage-gated sodium ion channel activity|upregulation of voltage-gated sodium channel activity|positive regulation of voltage-sensitive sodium channel|up regulation of voltage-sensitive sodium channel|up regulation of voltage-dependent sodium channel activity|activation of voltage-dependent sodium channel activity|positive regulation of voltage-dependent sodium channel activity|upregulation of voltage-gated sodium ion channel activity|up-regulation of voltage gated sodium channel activity|up regulation of voltage-gated sodium channel activity|activation of voltage-gated sodium channel activity|upregulation of voltage-sensitive sodium channel http://purl.obolibrary.org/obo/GO_1905152 GO:1905153 biolink:BiologicalProcess regulation of membrane invagination Any process that modulates the frequency, rate or extent of membrane invagination. go-plus.json http://purl.obolibrary.org/obo/GO_1905153 GO:1905154 biolink:BiologicalProcess negative regulation of membrane invagination Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. go-plus.json inhibition of membrane invagination|down regulation of membrane invagination|downregulation of membrane invagination|down-regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905154 GO:1905155 biolink:BiologicalProcess positive regulation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. go-plus.json up-regulation of membrane invagination|upregulation of membrane invagination|up regulation of membrane invagination|activation of membrane invagination http://purl.obolibrary.org/obo/GO_1905155 GO:1905156 biolink:BiologicalProcess negative regulation of photosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis. go-plus.json down-regulation of photosynthesis|downregulation of photosynthesis|down regulation of photosynthesis|inhibition of photosynthesis http://purl.obolibrary.org/obo/GO_1905156 GO:1905157 biolink:BiologicalProcess positive regulation of photosynthesis Any process that activates or increases the frequency, rate or extent of photosynthesis. go-plus.json up regulation of photosynthesis|upregulation of photosynthesis|activation of photosynthesis|up-regulation of photosynthesis http://purl.obolibrary.org/obo/GO_1905157 GO:0090305 biolink:BiologicalProcess nucleic acid phosphodiester bond hydrolysis The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. go-plus.json nucleic acid cleavage http://purl.obolibrary.org/obo/GO_0090305 GO:1905147 biolink:BiologicalProcess regulation of smooth muscle hypertrophy Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. go-plus.json http://purl.obolibrary.org/obo/GO_1905147 GO:1905148 biolink:BiologicalProcess negative regulation of smooth muscle hypertrophy Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. go-plus.json down regulation of smooth muscle hypertrophy|downregulation of smooth muscle hypertrophy|down-regulation of smooth muscle hypertrophy|inhibition of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_1905148 GO:0090306 biolink:BiologicalProcess meiotic spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis. go-plus.json meiotic spindle assembly|spindle assembly involved in meiosis http://purl.obolibrary.org/obo/GO_0090306 GO:0090303 biolink:BiologicalProcess positive regulation of wound healing Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. go-plus.json http://purl.obolibrary.org/obo/GO_0090303 GO:1905149 biolink:BiologicalProcess positive regulation of smooth muscle hypertrophy Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. go-plus.json upregulation of smooth muscle hypertrophy|up regulation of smooth muscle hypertrophy|activation of smooth muscle hypertrophy|up-regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_1905149 GO:0090304 biolink:BiologicalProcess nucleic acid metabolic process Any cellular metabolic process involving nucleic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0090304 GO:0090309 biolink:BiologicalProcess positive regulation of DNA methylation-dependent heterochromatin assembly Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. go-plus.json positive regulation of methylation-dependent chromatin silencing http://purl.obolibrary.org/obo/GO_0090309 GO:0090307 biolink:BiologicalProcess mitotic spindle assembly Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied. go-plus.json spindle assembly involved in mitosis http://purl.obolibrary.org/obo/GO_0090307 GO:0090308 biolink:BiologicalProcess regulation of DNA methylation-dependent heterochromatin assembly Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. go-plus.json regulation of methylation-dependent chromatin silencing http://purl.obolibrary.org/obo/GO_0090308 GO:0090301 biolink:BiologicalProcess negative regulation of neural crest formation Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. go-plus.json http://purl.obolibrary.org/obo/GO_0090301 GO:0090302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090302 GO:0090300 biolink:BiologicalProcess positive regulation of neural crest formation Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. go-plus.json http://purl.obolibrary.org/obo/GO_0090300 GO:1905160 biolink:BiologicalProcess obsolete positive regulation of Factor XII activation OBSOLETE. Any process that activates or increases the frequency, rate or extent of Factor XII activation. go-plus.json up-regulation of Factor XII activation|up-regulation of Hageman factor activation|upregulation of Factor XII activation|upregulation of Hageman factor activation|up regulation of Factor XII activation|activation of Factor XII activation|up regulation of Hageman factor activation|activation of Hageman factor activation|positive regulation of Hageman factor activation http://purl.obolibrary.org/obo/GO_1905160 GO:1905161 biolink:BiologicalProcess protein localization to phagocytic vesicle A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle. go-plus.json protein localization in phagocytic vesicle|protein localisation to phagosome|protein recruitment to phagosome|protein localisation to phagocytic vesicle|protein localisation in phagocytic vesicle http://purl.obolibrary.org/obo/GO_1905161 GO:1905162 biolink:BiologicalProcess regulation of phagosome maturation Any process that modulates the frequency, rate or extent of phagosome maturation. go-plus.json http://purl.obolibrary.org/obo/GO_1905162 GO:1905163 biolink:BiologicalProcess negative regulation of phagosome maturation Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation. go-plus.json downregulation of phagosome maturation|down regulation of phagosome maturation|inhibition of phagosome maturation|down-regulation of phagosome maturation http://purl.obolibrary.org/obo/GO_1905163 GO:1905164 biolink:BiologicalProcess positive regulation of phagosome maturation Any process that activates or increases the frequency, rate or extent of phagosome maturation. go-plus.json up regulation of phagosome maturation|upregulation of phagosome maturation|activation of phagosome maturation|up-regulation of phagosome maturation http://purl.obolibrary.org/obo/GO_1905164 GO:1905165 biolink:BiologicalProcess regulation of lysosomal protein catabolic process Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process. go-plus.json regulation of lysosomal protein catabolism|regulation of lysosomal protein degradation|regulation of cellular protein catabolism in lysosome|regulation of cellular protein degradation in lysosome|regulation of lysosomal proteolysis|regulation of proteolysis within lysosome|regulation of cellular protein breakdown in lysosome|regulation of cellular protein catabolic process in lysosome http://purl.obolibrary.org/obo/GO_1905165 GO:1905166 biolink:BiologicalProcess negative regulation of lysosomal protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process. go-plus.json inhibition of cellular protein catabolic process in lysosome|down-regulation of lysosomal proteolysis|negative regulation of lysosomal proteolysis|down-regulation of proteolysis within lysosome|inhibition of lysosomal protein catabolic process|negative regulation of proteolysis within lysosome|downregulation of lysosomal protein catabolism|down regulation of lysosomal protein degradation|down regulation of lysosomal protein catabolism|inhibition of lysosomal protein catabolism|negative regulation of cellular protein degradation in lysosome|down-regulation of cellular protein degradation in lysosome|down regulation of cellular protein catabolism in lysosome|downregulation of lysosomal protein degradation|downregulation of cellular protein catabolism in lysosome|inhibition of lysosomal proteolysis|down-regulation of cellular protein breakdown in lysosome|negative regulation of cellular protein breakdown in lysosome|inhibition of proteolysis within lysosome|down regulation of lysosomal protein catabolic process|downregulation of cellular protein degradation in lysosome|negative regulation of cellular protein catabolic process in lysosome|down-regulation of cellular protein catabolic process in lysosome|negative regulation of lysosomal protein degradation|down-regulation of lysosomal protein degradation|downregulation of lysosomal protein catabolic process|down regulation of lysosomal proteolysis|down-regulation of cellular protein catabolism in lysosome|down regulation of cellular protein degradation in lysosome|down regulation of proteolysis within lysosome|negative regulation of cellular protein catabolism in lysosome|inhibition of cellular protein degradation in lysosome|downregulation of cellular protein breakdown in lysosome|downregulation of lysosomal proteolysis|downregulation of proteolysis within lysosome|inhibition of lysosomal protein degradation|down-regulation of lysosomal protein catabolism|down regulation of cellular protein breakdown in lysosome|downregulation of cellular protein catabolic process in lysosome|negative regulation of lysosomal protein catabolism|inhibition of cellular protein catabolism in lysosome|inhibition of cellular protein breakdown in lysosome|down-regulation of lysosomal protein catabolic process|down regulation of cellular protein catabolic process in lysosome http://purl.obolibrary.org/obo/GO_1905166 GO:1905167 biolink:BiologicalProcess positive regulation of lysosomal protein catabolic process Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process. go-plus.json positive regulation of proteolysis within lysosome|up regulation of lysosomal protein catabolism|up-regulation of cellular protein degradation in lysosome|upregulation of cellular protein catabolic process in lysosome|activation of cellular protein degradation in lysosome|upregulation of lysosomal protein degradation|up-regulation of lysosomal protein catabolic process|activation of lysosomal proteolysis|activation of proteolysis within lysosome|upregulation of cellular protein catabolism in lysosome|up-regulation of cellular protein breakdown in lysosome|activation of cellular protein breakdown in lysosome|up-regulation of lysosomal proteolysis|upregulation of lysosomal protein catabolism|up-regulation of cellular protein catabolic process in lysosome|up-regulation of proteolysis within lysosome|activation of cellular protein catabolic process in lysosome|upregulation of lysosomal protein catabolic process|positive regulation of cellular protein degradation in lysosome|up regulation of lysosomal protein degradation|up regulation of cellular protein degradation in lysosome|positive regulation of lysosomal protein degradation|activation of lysosomal protein degradation|up regulation of cellular protein catabolism in lysosome|positive regulation of cellular protein catabolism in lysosome|positive regulation of cellular protein breakdown in lysosome|activation of cellular protein catabolism in lysosome|upregulation of lysosomal proteolysis|up regulation of cellular protein breakdown in lysosome|upregulation of proteolysis within lysosome|up-regulation of lysosomal protein catabolism|activation of lysosomal protein catabolism|positive regulation of cellular protein catabolic process in lysosome|up regulation of lysosomal protein catabolic process|up regulation of cellular protein catabolic process in lysosome|activation of lysosomal protein catabolic process|upregulation of cellular protein degradation in lysosome|up-regulation of lysosomal protein degradation|up regulation of lysosomal proteolysis|up-regulation of cellular protein catabolism in lysosome|up regulation of proteolysis within lysosome|upregulation of cellular protein breakdown in lysosome|positive regulation of lysosomal proteolysis|positive regulation of lysosomal protein catabolism http://purl.obolibrary.org/obo/GO_1905167 GO:1905168 biolink:BiologicalProcess positive regulation of double-strand break repair via homologous recombination Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination. go-plus.json up-regulation of HDR|upregulation of Rad51-dependent recombinational repair|up regulation of HRR|positive regulation of homology-directed repair|up-regulation of homologous recombinational repair|up-regulation of double-strand break repair via homologous recombination|activation of HRR|up regulation of homology-directed repair|positive regulation of HRR|upregulation of Rhp51-dependent recombinational repair|up-regulation of Rad51-dependent recombinational repair|upregulation of HDR|activation of Rad51-dependent recombinational repair|upregulation of homologous recombinational repair|upregulation of double-strand break repair via homologous recombination|upregulation of homology-directed repair|up-regulation of HRR|up-regulation of Rhp51-dependent recombinational repair|activation of Rhp51-dependent recombinational repair|up regulation of HDR|positive regulation of Rad51-dependent recombinational repair|positive regulation of HDR|activation of HDR|up regulation of homologous recombinational repair|up regulation of double-strand break repair via homologous recombination|up-regulation of homology-directed repair|up regulation of Rad51-dependent recombinational repair|positive regulation of homologous recombinational repair|activation of homologous recombinational repair|activation of double-strand break repair via homologous recombination|upregulation of HRR|activation of homology-directed repair|positive regulation of Rhp51-dependent recombinational repair|up regulation of Rhp51-dependent recombinational repair http://purl.obolibrary.org/obo/GO_1905168 GO:1905158 biolink:BiologicalProcess obsolete regulation of Factor XII activation OBSOLETE. Any process that modulates the frequency, rate or extent of Factor XII activation. go-plus.json regulation of Hageman factor activation http://purl.obolibrary.org/obo/GO_1905158 GO:0090316 biolink:BiologicalProcess positive regulation of intracellular protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090316 GO:1905159 biolink:BiologicalProcess obsolete negative regulation of Factor XII activation OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of Factor XII activation. go-plus.json down regulation of Factor XII activation|downregulation of Factor XII activation|down regulation of Hageman factor activation|downregulation of Hageman factor activation|down-regulation of Factor XII activation|down-regulation of Hageman factor activation|negative regulation of Hageman factor activation|inhibition of Factor XII activation|inhibition of Hageman factor activation http://purl.obolibrary.org/obo/GO_1905159 GO:0090317 biolink:BiologicalProcess negative regulation of intracellular protein transport Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090317 GO:0090314 biolink:BiologicalProcess positive regulation of protein targeting to membrane Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090314 GO:0090315 biolink:BiologicalProcess negative regulation of protein targeting to membrane Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090315 GO:0090318 biolink:BiologicalProcess regulation of chylomicron remodeling Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json http://purl.obolibrary.org/obo/GO_0090318 GO:0090319 biolink:BiologicalProcess positive regulation of chylomicron remodeling Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json http://purl.obolibrary.org/obo/GO_0090319 GO:0090312 biolink:BiologicalProcess positive regulation of protein deacetylation Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json positive regulation of protein amino acid deacetylation http://purl.obolibrary.org/obo/GO_0090312 GO:0090313 biolink:BiologicalProcess regulation of protein targeting to membrane Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090313 GO:0090310 biolink:BiologicalProcess negative regulation of DNA methylation-dependent heterochromatin assembly Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. go-plus.json negative regulation of methylation-dependent chromatin silencing http://purl.obolibrary.org/obo/GO_0090310 GO:0090311 biolink:BiologicalProcess regulation of protein deacetylation Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json regulation of protein amino acid deacetylation http://purl.obolibrary.org/obo/GO_0090311 GO:0090360 biolink:BiologicalProcess platelet-derived growth factor production The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090360 gocheck_do_not_annotate GO:1905170 biolink:BiologicalProcess negative regulation of protein localization to phagocytic vesicle Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle. go-plus.json down-regulation of protein localization to phagocytic vesicle|downregulation of protein recruitment to phagosome|downregulation of protein localisation to phagocytic vesicle|down-regulation of protein localisation in phagocytic vesicle|negative regulation of protein localisation in phagocytic vesicle|down regulation of protein recruitment to phagosome|down regulation of protein localisation to phagosome|down regulation of protein localisation to phagocytic vesicle|inhibition of protein recruitment to phagosome|inhibition of protein localisation to phagocytic vesicle|downregulation of protein localisation to phagosome|downregulation of protein localization to phagocytic vesicle|down-regulation of protein localization in phagocytic vesicle|negative regulation of protein localization in phagocytic vesicle|downregulation of protein localisation in phagocytic vesicle|down regulation of protein localization to phagocytic vesicle|inhibition of protein localization to phagocytic vesicle|down regulation of protein localisation in phagocytic vesicle|inhibition of protein localisation in phagocytic vesicle|down-regulation of protein localisation to phagosome|negative regulation of protein localisation to phagosome|downregulation of protein localization in phagocytic vesicle|down regulation of protein localization in phagocytic vesicle|down-regulation of protein recruitment to phagosome|negative regulation of protein recruitment to phagosome|inhibition of protein localization in phagocytic vesicle|inhibition of protein localisation to phagosome|down-regulation of protein localisation to phagocytic vesicle|negative regulation of protein localisation to phagocytic vesicle http://purl.obolibrary.org/obo/GO_1905170 GO:1905171 biolink:BiologicalProcess positive regulation of protein localization to phagocytic vesicle Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle. go-plus.json upregulation of protein localization in phagocytic vesicle|activation of protein localization to phagocytic vesicle|positive regulation of protein recruitment to phagosome|up-regulation of protein localisation in phagocytic vesicle|activation of protein localisation in phagocytic vesicle|positive regulation of protein localisation to phagocytic vesicle|up regulation of protein recruitment to phagosome|up regulation of protein localisation to phagocytic vesicle|upregulation of protein localisation to phagosome|up-regulation of protein localization in phagocytic vesicle|activation of protein localization in phagocytic vesicle|up regulation of protein localization to phagocytic vesicle|positive regulation of protein localisation in phagocytic vesicle|upregulation of protein recruitment to phagosome|up regulation of protein localisation in phagocytic vesicle|upregulation of protein localisation to phagocytic vesicle|up regulation of protein localisation to phagosome|positive regulation of protein localization in phagocytic vesicle|activation of protein localisation to phagosome|positive regulation of protein localisation to phagosome|upregulation of protein localization to phagocytic vesicle|up regulation of protein localization in phagocytic vesicle|up-regulation of protein recruitment to phagosome|up-regulation of protein localisation to phagocytic vesicle|activation of protein recruitment to phagosome|activation of protein localisation to phagocytic vesicle|upregulation of protein localisation in phagocytic vesicle|up-regulation of protein localisation to phagosome|up-regulation of protein localization to phagocytic vesicle http://purl.obolibrary.org/obo/GO_1905171 GO:1905172 biolink:MolecularActivity RISC complex binding Binding to a RISC complex. go-plus.json RNA-induced silencing complex binding http://purl.obolibrary.org/obo/GO_1905172 GO:1905173 biolink:BiologicalProcess eukaryotic translation initiation factor 2B complex assembly The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex. go-plus.json eif2B assembly|eIF-2B formation|eIF-2B assembly|eif2B formation|eukaryotic translation initiation factor 2B complex formation http://purl.obolibrary.org/obo/GO_1905173 GO:1905174 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell dedifferentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. go-plus.json regulation of vascular smooth muscle cell dedifferentiation http://purl.obolibrary.org/obo/GO_1905174 GO:1905175 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell dedifferentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. go-plus.json inhibition of vascular smooth muscle cell dedifferentiation|negative regulation of vascular smooth muscle cell dedifferentiation|down regulation of vascular smooth muscle cell dedifferentiation|downregulation of vascular smooth muscle cell dedifferentiation|down-regulation of vascular smooth muscle cell dedifferentiation http://purl.obolibrary.org/obo/GO_1905175 GO:1905176 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell dedifferentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. go-plus.json up-regulation of vascular smooth muscle cell dedifferentiation|positive regulation of vascular smooth muscle cell dedifferentiation|upregulation of vascular smooth muscle cell dedifferentiation|up regulation of vascular smooth muscle cell dedifferentiation|activation of vascular smooth muscle cell dedifferentiation http://purl.obolibrary.org/obo/GO_1905176 GO:1905177 biolink:BiologicalProcess tracheary element differentiation The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element. go-plus.json http://purl.obolibrary.org/obo/GO_1905177 GO:1905178 biolink:BiologicalProcess regulation of cardiac muscle tissue regeneration Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration. go-plus.json http://purl.obolibrary.org/obo/GO_1905178 GO:1905179 biolink:BiologicalProcess negative regulation of cardiac muscle tissue regeneration Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration. go-plus.json down-regulation of cardiac muscle tissue regeneration|downregulation of cardiac muscle tissue regeneration|down regulation of cardiac muscle tissue regeneration|inhibition of cardiac muscle tissue regeneration http://purl.obolibrary.org/obo/GO_1905179 GO:1905169 biolink:BiologicalProcess regulation of protein localization to phagocytic vesicle Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle. go-plus.json regulation of protein localisation to phagocytic vesicle|regulation of protein localisation to phagosome|regulation of protein localisation in phagocytic vesicle|regulation of protein localization in phagocytic vesicle|regulation of protein recruitment to phagosome http://purl.obolibrary.org/obo/GO_1905169 GO:0090369 biolink:MolecularActivity ornithine carbamoyltransferase inhibitor activity Binds to and stops, prevents, or reduces the activity of ornithine carbamoyltransferase. go-plus.json http://purl.obolibrary.org/obo/GO_0090369 GO:0090363 biolink:BiologicalProcess regulation of proteasome core complex assembly Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles. go-plus.json http://purl.obolibrary.org/obo/GO_0090363 GO:0090364 biolink:BiologicalProcess regulation of proteasome assembly Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex. go-plus.json http://purl.obolibrary.org/obo/GO_0090364 GO:0090361 biolink:BiologicalProcess regulation of platelet-derived growth factor production Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090361 GO:0090362 biolink:BiologicalProcess positive regulation of platelet-derived growth factor production Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090362 GO:0090367 biolink:BiologicalProcess negative regulation of mRNA modification Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. go-plus.json http://purl.obolibrary.org/obo/GO_0090367 GO:0090368 biolink:BiologicalProcess regulation of ornithine metabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090368 GO:0090365 biolink:BiologicalProcess regulation of mRNA modification Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. go-plus.json regulation of mRNA editing http://purl.obolibrary.org/obo/GO_0090365 GO:0090366 biolink:BiologicalProcess positive regulation of mRNA modification Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. go-plus.json http://purl.obolibrary.org/obo/GO_0090366 GO:0090370 biolink:BiologicalProcess negative regulation of cholesterol efflux Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0090370 GO:1905180 biolink:BiologicalProcess positive regulation of cardiac muscle tissue regeneration Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration. go-plus.json upregulation of cardiac muscle tissue regeneration|up-regulation of cardiac muscle tissue regeneration|activation of cardiac muscle tissue regeneration|up regulation of cardiac muscle tissue regeneration http://purl.obolibrary.org/obo/GO_1905180 GO:0090371 biolink:BiologicalProcess regulation of glycerol transport Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0090371 GO:1905181 biolink:BiologicalProcess regulation of urease activity Any process that modulates the frequency, rate or extent of urease activity. go-plus.json regulation of urea amidohydrolase activity http://purl.obolibrary.org/obo/GO_1905181 GO:1905182 biolink:BiologicalProcess positive regulation of urease activity Any process that activates or increases the frequency, rate or extent of urease activity. go-plus.json up regulation of urease activity|activation of urease activity|upregulation of urea amidohydrolase activity|up-regulation of urease activity|activation of urea amidohydrolase activity|up-regulation of urea amidohydrolase activity|upregulation of urease activity|positive regulation of urea amidohydrolase activity|up regulation of urea amidohydrolase activity http://purl.obolibrary.org/obo/GO_1905182 GO:1905183 biolink:BiologicalProcess negative regulation of protein serine/threonine phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity. go-plus.json down regulation of serine/threonine specific protein phosphatase activity|down regulation of protein serine/threonine phosphatase activity|inhibition of serine/threonine specific protein phosphatase activity|downregulation of protein serine/threonine phosphatase activity|down-regulation of protein serine/threonine phosphatase activity|down-regulation of serine/threonine specific protein phosphatase activity|negative regulation of serine/threonine specific protein phosphatase activity|inhibition of protein serine/threonine phosphatase activity|downregulation of serine/threonine specific protein phosphatase activity http://purl.obolibrary.org/obo/GO_1905183 GO:1905184 biolink:BiologicalProcess positive regulation of protein serine/threonine phosphatase activity Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity. go-plus.json upregulation of protein serine/threonine phosphatase activity|upregulation of serine/threonine specific protein phosphatase activity|up regulation of protein serine/threonine phosphatase activity|activation of protein serine/threonine phosphatase activity|activation of serine/threonine specific protein phosphatase activity|up-regulation of serine/threonine specific protein phosphatase activity|up-regulation of protein serine/threonine phosphatase activity|positive regulation of serine/threonine specific protein phosphatase activity|up regulation of serine/threonine specific protein phosphatase activity http://purl.obolibrary.org/obo/GO_1905184 GO:1905185 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905185 GO:1905186 biolink:BiologicalProcess regulation of metaphase/anaphase transition of meiosis I Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I. go-plus.json regulation of meiosis I metaphase/anaphase transition|regulation of first meiotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1905186 GO:1905187 biolink:BiologicalProcess negative regulation of metaphase/anaphase transition of meiosis I Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_1905187 GO:1905188 biolink:BiologicalProcess positive regulation of metaphase/anaphase transition of meiosis I Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I. go-plus.json positive regulation of meiosis I metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1905188 GO:1905189 biolink:BiologicalProcess regulation of metaphase/anaphase transition of meiosis II Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II. go-plus.json regulation of meiosis II metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1905189 GO:0090374 biolink:BiologicalProcess oligopeptide export from mitochondrion The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0090374 CHEBI:5373 biolink:ChemicalSubstance (S)-glaucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_5373 GO:0090375 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. go-plus.json negative regulation of transcription from RNA polymerase II promoter in response to iron deficiency http://purl.obolibrary.org/obo/GO_0090375 GO:0090372 biolink:BiologicalProcess positive regulation of glycerol transport Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0090372 GO:0090373 biolink:BiologicalProcess negative regulation of glycerol transport Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0090373 GO:0090378 biolink:BiologicalProcess seed trichome elongation The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090378 GO:0090379 biolink:BiologicalProcess secondary cell wall biogenesis involved in seed trichome differentiation A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete. go-plus.json secondary cell wall biosynthesis involved in seed trichome differentiation|seed trichome secondary wall biosynthesis http://purl.obolibrary.org/obo/GO_0090379 GO:0090376 biolink:BiologicalProcess seed trichome differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function. go-plus.json seed hair differentiation|seed trichome development|cotton fiber development http://purl.obolibrary.org/obo/GO_0090376 GO:0090377 biolink:BiologicalProcess seed trichome initiation The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis. go-plus.json seed trichome fate commitment http://purl.obolibrary.org/obo/GO_0090377 GO:1905190 biolink:BiologicalProcess negative regulation of metaphase/anaphase transition of meiosis II Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II. go-plus.json negative regulation of meiosis II metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1905190 GO:1905191 biolink:BiologicalProcess positive regulation of metaphase/anaphase transition of meiosis II Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II. go-plus.json positive regulation of meiosis II metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1905191 GO:1905192 biolink:BiologicalProcess regulation of chloroplast fission Any process that modulates the frequency, rate or extent of chloroplast fission. go-plus.json regulation of chloroplast division http://purl.obolibrary.org/obo/GO_1905192 GO:1905193 biolink:BiologicalProcess negative regulation of chloroplast fission Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission. go-plus.json down regulation of chloroplast fission|downregulation of chloroplast fission|down-regulation of chloroplast division|negative regulation of chloroplast division|down-regulation of chloroplast fission|downregulation of chloroplast division|inhibition of chloroplast fission|down regulation of chloroplast division|inhibition of chloroplast division http://purl.obolibrary.org/obo/GO_1905193 GO:1905194 biolink:BiologicalProcess positive regulation of chloroplast fission Any process that activates or increases the frequency, rate or extent of chloroplast fission. go-plus.json upregulation of chloroplast division|upregulation of chloroplast fission|activation of chloroplast division|up-regulation of chloroplast division|up regulation of chloroplast fission|activation of chloroplast fission|positive regulation of chloroplast division|up regulation of chloroplast division|up-regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_1905194 GO:1905195 biolink:BiologicalProcess obsolete regulation of ATPase activity, uncoupled OBSOLETE. Any process that modulates the frequency, rate or extent of ATPase activity, uncoupled. go-plus.json regulation of adenylpyrophosphatase activity http://purl.obolibrary.org/obo/GO_1905195 GO:1905196 biolink:BiologicalProcess obsolete positive regulation of ATPase activity, uncoupled OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled. go-plus.json up regulation of adenylpyrophosphatase activity|up regulation of ATPase activity, uncoupled|upregulation of adenylpyrophosphatase activity|upregulation of ATPase activity, uncoupled|up-regulation of adenylpyrophosphatase activity|activation of ATPase activity, uncoupled|up-regulation of ATPase activity, uncoupled|activation of adenylpyrophosphatase activity|positive regulation of adenylpyrophosphatase activity http://purl.obolibrary.org/obo/GO_1905196 GO:1905197 biolink:BiologicalProcess endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid. go-plus.json endocannabinoid signalling pathway involved in retrograde trans-synaptic signaling by endocannabinoid http://purl.obolibrary.org/obo/GO_1905197 GO:1905198 biolink:BiologicalProcess manchette assembly The aggregation, arrangement and bonding together of a set of components to form a manchette. go-plus.json manchette formation http://purl.obolibrary.org/obo/GO_1905198 GO:1905199 biolink:BiologicalProcess manchette disassembly The disaggregation of a manchette into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_1905199 GO:0090349 biolink:BiologicalProcess negative regulation of cellular organohalogen metabolic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090349 GO:0090347 biolink:BiologicalProcess regulation of cellular organohalogen metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090347 GO:0090348 biolink:BiologicalProcess regulation of cellular organofluorine metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090348 GO:0090341 biolink:BiologicalProcess negative regulation of secretion of lysosomal enzymes Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090341 GO:0016363 biolink:CellularComponent nuclear matrix The dense fibrillar network lying on the inner side of the nuclear membrane. Wikipedia:Nuclear_matrix go-plus.json nucleoskeleton http://purl.obolibrary.org/obo/GO_0016363 GO:0090342 biolink:BiologicalProcess regulation of cell aging Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan. go-plus.json http://purl.obolibrary.org/obo/GO_0090342 GO:0090340 biolink:BiologicalProcess positive regulation of secretion of lysosomal enzymes Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090340 GO:0090345 biolink:BiologicalProcess cellular organohalogen metabolic process The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090345 GO:0090346 biolink:BiologicalProcess cellular organofluorine metabolic process The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090346 GO:0016360 biolink:BiologicalProcess sensory organ precursor cell fate determination The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json sense organ precursor cell fate determination http://purl.obolibrary.org/obo/GO_0016360 GO:0090343 biolink:BiologicalProcess positive regulation of cell aging Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan. go-plus.json http://purl.obolibrary.org/obo/GO_0090343 GO:0016361 biolink:MolecularActivity activin receptor activity, type I Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals. go-plus.json type I activin receptor activity http://purl.obolibrary.org/obo/GO_0016361 GO:0016362 biolink:MolecularActivity activin receptor activity, type II Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor. Reactome:R-HSA-201443 go-plus.json type II activin receptor activity http://purl.obolibrary.org/obo/GO_0016362 GO:0090344 biolink:BiologicalProcess negative regulation of cell aging Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan. go-plus.json http://purl.obolibrary.org/obo/GO_0090344 GO:0031999 biolink:BiologicalProcess negative regulation of fatty acid beta-oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation. go-plus.json down regulation of fatty acid beta-oxidation|downregulation of fatty acid beta-oxidation|down-regulation of fatty acid beta-oxidation|inhibition of fatty acid beta-oxidation http://purl.obolibrary.org/obo/GO_0031999 GO:0031997 biolink:MolecularActivity N-terminal myristoylation domain binding Binding to the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin. go-plus.json http://purl.obolibrary.org/obo/GO_0031997 GO:0031998 biolink:BiologicalProcess regulation of fatty acid beta-oxidation Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation. go-plus.json http://purl.obolibrary.org/obo/GO_0031998 GO:0031995 biolink:MolecularActivity insulin-like growth factor II binding Binding to insulin-like growth factor II. go-plus.json IGF-II binding http://purl.obolibrary.org/obo/GO_0031995 goslim_chembl GO:0031996 biolink:MolecularActivity thioesterase binding Binding to a thioesterase. go-plus.json thiolesterase binding http://purl.obolibrary.org/obo/GO_0031996 GO:0090358 biolink:BiologicalProcess positive regulation of tryptophan metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. go-plus.json positive regulation of tryptophan metabolism http://purl.obolibrary.org/obo/GO_0090358 GO:0090359 biolink:BiologicalProcess negative regulation of abscisic acid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid. go-plus.json negative regulation of abscisic acid biosynthesis http://purl.obolibrary.org/obo/GO_0090359 GO:0090352 biolink:BiologicalProcess regulation of nitrate assimilation Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances. go-plus.json http://purl.obolibrary.org/obo/GO_0090352 GO:0031993 biolink:MolecularActivity light transducer activity Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031993 GO:0031994 biolink:MolecularActivity insulin-like growth factor I binding Binding to insulin-like growth factor I. go-plus.json IGF-I binding http://purl.obolibrary.org/obo/GO_0031994 goslim_chembl GO:0090353 biolink:MolecularActivity polygalacturonase inhibitor activity Binds to and stops, prevents or reduces the activity of polygalacturonase. go-plus.json http://purl.obolibrary.org/obo/GO_0090353 GO:0031991 biolink:BiologicalProcess regulation of actomyosin contractile ring contraction Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle. go-plus.json regulation of contractile ring contraction involved in cell cycle cytokinesis|regulation of actomyosin contractile ring constriction|regulation of contractile ring contraction involved in cytokinesis during cell cycle http://purl.obolibrary.org/obo/GO_0031991 GO:0090350 biolink:BiologicalProcess negative regulation of cellular organofluorine metabolic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090350 GO:0090351 biolink:BiologicalProcess seedling development The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge. PO:0008037 go-plus.json http://purl.obolibrary.org/obo/GO_0090351 GO:0031992 biolink:MolecularActivity energy transducer activity The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell. go-plus.json light harvesting activity|photon capture http://purl.obolibrary.org/obo/GO_0031992 goslim_pir GO:0090356 biolink:BiologicalProcess negative regulation of auxin metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth. go-plus.json negative regulation of auxin metabolism http://purl.obolibrary.org/obo/GO_0090356 GO:0031990 biolink:BiologicalProcess mRNA export from nucleus in response to heat stress The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export. go-plus.json mRNA export from nucleus during heat stress|mRNA export from cell nucleus during heat stress http://purl.obolibrary.org/obo/GO_0031990 GO:0090357 biolink:BiologicalProcess regulation of tryptophan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. go-plus.json regulation of tryptophan metabolism http://purl.obolibrary.org/obo/GO_0090357 GO:0090354 biolink:BiologicalProcess regulation of auxin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth. go-plus.json regulation of auxin metabolism http://purl.obolibrary.org/obo/GO_0090354 GO:0090355 biolink:BiologicalProcess positive regulation of auxin metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth. go-plus.json positive regulation of auxin metabolism http://purl.obolibrary.org/obo/GO_0090355 GO:2000508 biolink:BiologicalProcess regulation of dendritic cell chemotaxis Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000508 GO:2000509 biolink:BiologicalProcess negative regulation of dendritic cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000509 UBERON:0018144 biolink:AnatomicalEntity cervical rib A rib that is attached to a cervical vertebra. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018144 UBERON:0018142 biolink:AnatomicalEntity caudal vertebra endochondral element Any vertebra endochondral element that is part of the caudal region of the vertebral column (tail or coccyx). go-plus.json coccyx vertebra element|coccygeal vertebra element|tail vertebra element|caudal vertebra element http://purl.obolibrary.org/obo/UBERON_0018142 UBERON:0018143 biolink:AnatomicalEntity transverse process of cervical vertebra A transverse process that is part of a cervical vertebra go-plus.json http://purl.obolibrary.org/obo/UBERON_0018143 GO:2000500 biolink:BiologicalProcess obsolete positive regulation of induction of apoptosis in response to chemical stimulus OBSOLETE. Any process that activates or increases the frequency, rate or extent of induction of apoptosis in response to chemical stimulus. go-plus.json positive regulation of induction of apoptosis in response to chemical substance|positive regulation of induction of apoptosis in response to chemical stimulus http://purl.obolibrary.org/obo/GO_2000500 GO:2000501 biolink:BiologicalProcess regulation of natural killer cell chemotaxis Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000501 GO:2000502 biolink:BiologicalProcess negative regulation of natural killer cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000502 GO:2000503 biolink:BiologicalProcess positive regulation of natural killer cell chemotaxis Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000503 GO:2000504 biolink:BiologicalProcess positive regulation of blood vessel remodeling Any process that activates or increases the frequency, rate or extent of blood vessel remodeling. go-plus.json http://purl.obolibrary.org/obo/GO_2000504 GO:2000505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000505 GO:2000506 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000506 GO:2000507 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000507 CHEBI:41308 biolink:ChemicalSubstance benzophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_41308 chebi_ph7_3 CHEBI:16337 biolink:ChemicalSubstance phosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16337 CL:0008007 biolink:Cell visceral muscle cell A muscle cell that is part of some visceral muscle go-plus.json http://purl.obolibrary.org/obo/CL_0008007 CHEBI:16338 biolink:ChemicalSubstance 4-hydroxy-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16338 CL:0008008 biolink:Cell striated visceral muscle cell A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. go-plus.json http://purl.obolibrary.org/obo/CL_0008008 CHEBI:16335 biolink:ChemicalSubstance adenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16335 chebi_ph7_3 CHEBI:16336 biolink:ChemicalSubstance hyaluronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16336 CL:0008009 biolink:Cell transversely striated visceral muscle cell A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. go-plus.json http://purl.obolibrary.org/obo/CL_0008009 CHEBI:16333 biolink:ChemicalSubstance 2-arylpropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16333 CL:0008002 biolink:Cell skeletal muscle fiber A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/CL_0008002 CL:0008003 biolink:Cell somatic muscle myotube A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells. go-plus.json http://purl.obolibrary.org/obo/CL_0008003 CL:0008004 biolink:Cell somatic muscle cell A muscle cell that is part of some somatic muscle. go-plus.json http://purl.obolibrary.org/obo/CL_0008004 CHEBI:16331 biolink:ChemicalSubstance phloretate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16331 chebi_ph7_3 CHEBI:16332 biolink:ChemicalSubstance D-xylulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16332 CHEBI:16330 biolink:ChemicalSubstance 17beta-hydroxy-5alpha-androstan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16330 chebi_ph7_3 CL:0008000 biolink:Cell non-striated muscle cell Any muscle cell in which the fibers are not organised into sarcomeres. go-plus.json http://purl.obolibrary.org/obo/CL_0008000 CHEBI:90277 biolink:ChemicalSubstance (2E)-tricosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90277 CL:0008001 biolink:Cell hematopoietic precursor cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. go-plus.json http://purl.obolibrary.org/obo/CL_0008001 GO:2000519 biolink:BiologicalProcess positive regulation of T-helper 1 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation. go-plus.json positive regulation of Th1 cell activation http://purl.obolibrary.org/obo/GO_2000519 UBERON:0018135 biolink:AnatomicalEntity fibrocollagenous connective tissue go-plus.json http://purl.obolibrary.org/obo/UBERON_0018135 CHEBI:90262 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90262 chebi_ph7_3 UBERON:0018132 biolink:AnatomicalEntity tail fat pad Encapsulated adipose tissue that is part of a tail. go-plus.json tail fat depot http://purl.obolibrary.org/obo/UBERON_0018132 GO:2000511 biolink:BiologicalProcess regulation of granzyme A production Any process that modulates the frequency, rate or extent of granzyme A production. go-plus.json http://purl.obolibrary.org/obo/GO_2000511 GO:2000512 biolink:BiologicalProcess negative regulation of granzyme A production Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production. go-plus.json http://purl.obolibrary.org/obo/GO_2000512 GO:2000513 biolink:BiologicalProcess positive regulation of granzyme A production Any process that activates or increases the frequency, rate or extent of granzyme A production. go-plus.json http://purl.obolibrary.org/obo/GO_2000513 GO:2000514 biolink:BiologicalProcess regulation of CD4-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000514 GO:2000515 biolink:BiologicalProcess negative regulation of CD4-positive, alpha-beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000515 GO:2000516 biolink:BiologicalProcess positive regulation of CD4-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000516 GO:2000517 biolink:BiologicalProcess regulation of T-helper 1 cell activation Any process that modulates the frequency, rate or extent of T-helper 1 cell activation. go-plus.json regulation of Th1 cell activation http://purl.obolibrary.org/obo/GO_2000517 GO:2000518 biolink:BiologicalProcess negative regulation of T-helper 1 cell activation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation. go-plus.json negative regulation of Th1 cell activation http://purl.obolibrary.org/obo/GO_2000518 CHEBI:16329 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16329 CL:0008017 biolink:Cell adult skeletal muscle myoblast A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. go-plus.json myogenic precursor cell http://purl.obolibrary.org/obo/CL_0008017 CHEBI:16326 biolink:ChemicalSubstance alpha-D-hexose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16326 CL:0008018 biolink:Cell somatic muscle myoblast A myoblast that is commited to developing into a somatic muscle. go-plus.json http://purl.obolibrary.org/obo/CL_0008018 CHEBI:16327 biolink:ChemicalSubstance 2-oxosuccinamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16327 CHEBI:16324 biolink:ChemicalSubstance rifamycin O go-plus.json http://purl.obolibrary.org/obo/CHEBI_16324 chebi_ph7_3 CL:0008019 biolink:Cell mesenchymal cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. go-plus.json mesenchyme cell http://purl.obolibrary.org/obo/CL_0008019 GO:2000510 biolink:BiologicalProcess positive regulation of dendritic cell chemotaxis Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000510 CHEBI:16325 biolink:ChemicalSubstance lithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16325 CHEBI:16322 biolink:ChemicalSubstance myo-inositol 1,3,4,5,6-pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16322 CHEBI:16320 biolink:ChemicalSubstance (R)-3-aminoisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16320 CL:0008016 biolink:Cell activated skeletal muscle satellite cell A skeletal muscle cell that has become mitotically active - typically following muscle damage. go-plus.json http://purl.obolibrary.org/obo/CL_0008016 CHEBI:16321 biolink:ChemicalSubstance 4-carboxy-2-hydroxyhexa-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16321 CHEBI:90264 biolink:ChemicalSubstance L-3-sulfolactaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_90264 CHEBI:90265 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90265 chebi_ph7_3 CL:0008011 biolink:Cell skeletal muscle satellite stem cell A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. go-plus.json http://purl.obolibrary.org/obo/CL_0008011 CL:0008012 biolink:Cell quiescent skeletal muscle satellite cell A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. go-plus.json http://purl.obolibrary.org/obo/CL_0008012 CHEBI:90266 biolink:ChemicalSubstance tricosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90266 CHEBI:90292 biolink:ChemicalSubstance beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90292 chebi_ph7_3 UBERON:0018120 biolink:AnatomicalEntity right renal medulla interstitium A renal medulla interstitium that is part of a right kidney. go-plus.json medullary interstitial tissue of right kidney http://purl.obolibrary.org/obo/UBERON_0018120 CHEBI:5391 biolink:ChemicalSubstance glucagon go-plus.json http://purl.obolibrary.org/obo/CHEBI_5391 GO:2000522 biolink:BiologicalProcess positive regulation of immunological synapse formation Any process that activates or increases the frequency, rate or extent of immunological synapse formation. go-plus.json positive regulation of formation of immunological synapse http://purl.obolibrary.org/obo/GO_2000522 GO:2000523 biolink:BiologicalProcess regulation of T cell costimulation Any process that modulates the frequency, rate or extent of T cell costimulation. go-plus.json regulation of T-cell costimulation|regulation of T cell co-stimulation|regulation of T-lymphocyte costimulation|regulation of T lymphocyte costimulation|regulation of T-cell co-stimulation http://purl.obolibrary.org/obo/GO_2000523 GO:2000524 biolink:BiologicalProcess negative regulation of T cell costimulation Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation. go-plus.json negative regulation of T lymphocyte costimulation|negative regulation of T cell co-stimulation|negative regulation of T-cell costimulation|negative regulation of T-lymphocyte costimulation|negative regulation of T-cell co-stimulation http://purl.obolibrary.org/obo/GO_2000524 GO:2000525 biolink:BiologicalProcess positive regulation of T cell costimulation Any process that activates or increases the frequency, rate or extent of T cell costimulation. go-plus.json positive regulation of T lymphocyte costimulation|positive regulation of T cell co-stimulation|positive regulation of T-cell co-stimulation|positive regulation of T-cell costimulation|positive regulation of T-lymphocyte costimulation http://purl.obolibrary.org/obo/GO_2000525 GO:2000526 biolink:BiologicalProcess positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation. go-plus.json positive regulation of glycoprotein biosynthetic process of formation of immunological synapse|positive regulation of glycoprotein biosynthetic process of immunological synapse formation http://purl.obolibrary.org/obo/GO_2000526 GO:2000527 biolink:BiologicalProcess regulation of myeloid dendritic cell chemotaxis Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000527 GO:2000528 biolink:BiologicalProcess negative regulation of myeloid dendritic cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000528 GO:2000529 biolink:BiologicalProcess positive regulation of myeloid dendritic cell chemotaxis Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000529 CHEBI:16359 biolink:ChemicalSubstance cholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16359 GO:2000520 biolink:BiologicalProcess regulation of immunological synapse formation Any process that modulates the frequency, rate or extent of immunological synapse formation. go-plus.json regulation of formation of immunological synapse http://purl.obolibrary.org/obo/GO_2000520 CHEBI:16357 biolink:ChemicalSubstance 3-(pyrazol-1-yl)-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16357 GO:2000521 biolink:BiologicalProcess negative regulation of immunological synapse formation Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation. go-plus.json negative regulation of formation of immunological synapse http://purl.obolibrary.org/obo/GO_2000521 CHEBI:16358 biolink:ChemicalSubstance (R)-vicianin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16358 chebi_ph7_3 CHEBI:16355 biolink:ChemicalSubstance 1-iodo-2-methoxybenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16355 chebi_ph7_3 CHEBI:16356 biolink:ChemicalSubstance 3',5'-cyclic GMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16356 CHEBI:5385 biolink:ChemicalSubstance gliotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_5385 chebi_ph7_3 OBO:GOCHE_22587 biolink:OntologyClass substance with antiviral agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_22587 3_STAR CHEBI:16353 biolink:ChemicalSubstance sinapine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16353 chebi_ph7_3 CHEBI:16354 biolink:ChemicalSubstance N-methylhydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16354 chebi_ph7_3 CHEBI:16351 biolink:ChemicalSubstance 2-(alpha-D-mannosyl)-3-phosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16351 CHEBI:16352 biolink:ChemicalSubstance 4-hydroxy-1-pyrroline-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16352 CHEBI:5386 biolink:ChemicalSubstance globin go-plus.json http://purl.obolibrary.org/obo/CHEBI_5386 CHEBI:16350 biolink:ChemicalSubstance 2'-deoxyribonucleoside 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16350 UBERON:0018113 biolink:AnatomicalEntity left kidney interstitium A kidney interstitium that is part of a left kidney. go-plus.json left renal stroma|stroma of left kidney http://purl.obolibrary.org/obo/UBERON_0018113 UBERON:0018114 biolink:AnatomicalEntity right kidney interstitium A kidney interstitium that is part of a right kidney. go-plus.json right renal stroma|stroma of right kidney http://purl.obolibrary.org/obo/UBERON_0018114 UBERON:0018111 biolink:AnatomicalEntity muscle layer of rectum A muscle layer that is part of the rectum go-plus.json muscularis externa of rectum|muscular coat of rectum|rectal muscularis propria|tunica muscularis (rectum)|tunica muscularis recti http://purl.obolibrary.org/obo/UBERON_0018111 UBERON:0018112 biolink:AnatomicalEntity rectum smooth muscle tissue Any portion of smooth muscle tissue that is part of the rectum go-plus.json rectal smooth muscle tissue|smooth muscle of rectum|rectum smooth muscle http://purl.obolibrary.org/obo/UBERON_0018112 GO:2000533 biolink:BiologicalProcess negative regulation of renal albumin absorption Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption. go-plus.json http://purl.obolibrary.org/obo/GO_2000533 GO:2000534 biolink:BiologicalProcess positive regulation of renal albumin absorption Any process that activates or increases the frequency, rate or extent of renal albumin absorption. go-plus.json http://purl.obolibrary.org/obo/GO_2000534 UBERON:0018119 biolink:AnatomicalEntity left renal medulla interstitium A renal medulla interstitium that is part of a left kidney. go-plus.json medullary interstitial tissue of left kidney http://purl.obolibrary.org/obo/UBERON_0018119 GO:2000535 biolink:BiologicalProcess regulation of entry of bacterium into host cell Any process that modulates the frequency, rate or extent of entry of bacterium into host cell. go-plus.json regulation of bacterial entry into host cell|regulation of invasion of bacteria into host cell http://purl.obolibrary.org/obo/GO_2000535 CHEBI:31966 biolink:ChemicalSubstance pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_31966 GO:2000536 biolink:BiologicalProcess negative regulation of entry of bacterium into host cell Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell. go-plus.json negative regulation of invasion of bacteria into host cell|negative regulation of bacterial entry into host cell http://purl.obolibrary.org/obo/GO_2000536 GO:2000537 biolink:BiologicalProcess regulation of B cell chemotaxis Any process that modulates the frequency, rate or extent of B cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000537 CHEBI:31967 biolink:ChemicalSubstance pelargonidin 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_31967 UBERON:0018117 biolink:AnatomicalEntity left renal cortex interstitium A renal cortex interstitium that is part of a left kidney. go-plus.json cortical interstitial tissue of left kidney http://purl.obolibrary.org/obo/UBERON_0018117 UBERON:0018118 biolink:AnatomicalEntity right renal cortex interstitium A renal cortex interstitium that is part of a right kidney. go-plus.json cortical interstitial tissue of right kidney http://purl.obolibrary.org/obo/UBERON_0018118 GO:2000538 biolink:BiologicalProcess positive regulation of B cell chemotaxis Any process that activates or increases the frequency, rate or extent of B cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000538 CHEBI:31968 biolink:ChemicalSubstance pelargonidin 3-O-rutinoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_31968 CHEBI:31969 biolink:ChemicalSubstance pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_31969 GO:2000539 biolink:BiologicalProcess regulation of protein geranylgeranylation Any process that modulates the frequency, rate or extent of protein geranylgeranylation. go-plus.json regulation of C-terminal protein geranylgeranylation|regulation of protein amino acid geranylgeranylation http://purl.obolibrary.org/obo/GO_2000539 UBERON:0018115 biolink:AnatomicalEntity left renal pelvis A renal pelvis that is part of a left ureter. go-plus.json renal pelvis of left kidney|pelvis of left ureter http://purl.obolibrary.org/obo/UBERON_0018115 UBERON:0018116 biolink:AnatomicalEntity right renal pelvis A renal pelvis that is part of a right ureter. go-plus.json pelvis of right kidney|pelvis of right ureter http://purl.obolibrary.org/obo/UBERON_0018116 PR:000003035 biolink:Protein cellular tumor antigen p53 A protein that is a translation product of the human TP53 gene or a 1:1 ortholog thereof. go-plus.json P53|TP53|tumor suppressor p53|phosphoprotein p53|antigen NY-CO-13|Trp53 http://purl.obolibrary.org/obo/PR_000003035 CHEBI:16348 biolink:ChemicalSubstance 3-nitropropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16348 CHEBI:16349 biolink:ChemicalSubstance L-citrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16349 GO:2000530 biolink:BiologicalProcess obsolete positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of insulin secretion involved in cellular response to glucose stimulus. go-plus.json positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of regulation of insulin secretion in response to glucose http://purl.obolibrary.org/obo/GO_2000530 CHEBI:16346 biolink:ChemicalSubstance (S)-1-phenylethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16346 chebi_ph7_3 GO:2000531 biolink:BiologicalProcess obsolete regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of the biosynthesis of fatty acids, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_2000531 CHEBI:16347 biolink:ChemicalSubstance (R)-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16347 chebi_ph7_3 GO:2000532 biolink:BiologicalProcess regulation of renal albumin absorption Any process that modulates the frequency, rate or extent of renal albumin absorption. go-plus.json http://purl.obolibrary.org/obo/GO_2000532 CHEBI:16344 biolink:ChemicalSubstance guanidinoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16344 CHEBI:16345 biolink:ChemicalSubstance 3-sulfino-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16345 CHEBI:16342 biolink:ChemicalSubstance L-5-carboxymethylhydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16342 CHEBI:16343 biolink:ChemicalSubstance phenylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16343 GO:1905100 biolink:BiologicalProcess regulation of apoptosome assembly Any process that modulates the frequency, rate or extent of apoptosome assembly. go-plus.json regulation of apoptosome formation http://purl.obolibrary.org/obo/GO_1905100 GO:1905101 biolink:BiologicalProcess negative regulation of apoptosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly. go-plus.json down regulation of apoptosome assembly|downregulation of apoptosome assembly|down-regulation of apoptosome formation|negative regulation of apoptosome formation|down-regulation of apoptosome assembly|downregulation of apoptosome formation|inhibition of apoptosome assembly|down regulation of apoptosome formation|inhibition of apoptosome formation http://purl.obolibrary.org/obo/GO_1905101 GO:1905102 biolink:BiologicalProcess positive regulation of apoptosome assembly Any process that activates or increases the frequency, rate or extent of apoptosome assembly. go-plus.json upregulation of apoptosome assembly|up-regulation of apoptosome formation|activation of apoptosome formation|up regulation of apoptosome assembly|activation of apoptosome assembly|positive regulation of apoptosome formation|up regulation of apoptosome formation|up-regulation of apoptosome assembly|upregulation of apoptosome formation http://purl.obolibrary.org/obo/GO_1905102 GO:1905110 biolink:BiologicalProcess negative regulation of pulmonary blood vessel remodeling Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling. go-plus.json down regulation of pulmonary blood vessel remodeling|downregulation of pulmonary blood vessel remodeling|down-regulation of pulmonary blood vessel remodeling|inhibition of pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_1905110 GO:1905111 biolink:BiologicalProcess positive regulation of pulmonary blood vessel remodeling Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling. go-plus.json upregulation of pulmonary blood vessel remodeling|up regulation of pulmonary blood vessel remodeling|activation of pulmonary blood vessel remodeling|up-regulation of pulmonary blood vessel remodeling http://purl.obolibrary.org/obo/GO_1905111 GO:1905112 biolink:BiologicalProcess obsolete regulation of centromere clustering at the mitotic nuclear envelope OBSOLETE. Any process that modulates the frequency, rate or extent of centromere clustering at the nuclear envelope. go-plus.json regulation of centromere-SPB clustering|regulation of kinetochore clustering at SPB|regulation of kinetochore clustering at spindle pole body|regulation of rabl configuration|regulation of kinetochore localization at spindle pole body|regulation of kinetochore clustering at the old mitotic spindle pole body|regulation of centromere clustering at the nuclear periphery http://purl.obolibrary.org/obo/GO_1905112 GO:1905113 biolink:BiologicalProcess obsolete positive regulation of centromere clustering at the mitotic nuclear envelope OBSOLETE. Any process that activates or increases the frequency, rate or extent of centromere clustering at the nuclear envelope. go-plus.json upregulation of kinetochore clustering at spindle pole body|upregulation of kinetochore clustering at SPB|activation of rabl configuration|activation of kinetochore localization at spindle pole body|activation of kinetochore clustering at the old mitotic spindle pole body|upregulation of centromere clustering at the nuclear periphery|up regulation of centromere clustering at the nuclear envelope|activation of centromere clustering at the nuclear envelope|positive regulation of rabl configuration|up regulation of centromere-SPB clustering|up-regulation of kinetochore localization at spindle pole body|up-regulation of kinetochore clustering at the old mitotic spindle pole body|up regulation of rabl configuration|positive regulation of centromere-SPB clustering|up regulation of kinetochore clustering at SPB|up regulation of kinetochore clustering at spindle pole body|activation of centromere clustering at the nuclear periphery|up-regulation of centromere clustering at the nuclear periphery|positive regulation of kinetochore clustering at SPB|positive regulation of kinetochore clustering at spindle pole body|activation of centromere-SPB clustering|up-regulation of centromere clustering at the nuclear envelope|activation of kinetochore clustering at spindle pole body|upregulation of kinetochore clustering at the old mitotic spindle pole body|activation of kinetochore clustering at SPB|upregulation of kinetochore localization at spindle pole body|upregulation of rabl configuration|up-regulation of centromere-SPB clustering|positive regulation of centromere clustering at the nuclear periphery|up-regulation of kinetochore clustering at spindle pole body|up-regulation of kinetochore clustering at SPB|up regulation of centromere clustering at the nuclear periphery|upregulation of centromere clustering at the nuclear envelope|up regulation of kinetochore clustering at the old mitotic spindle pole body|up-regulation of rabl configuration|up regulation of kinetochore localization at spindle pole body|positive regulation of kinetochore localization at spindle pole body|upregulation of centromere-SPB clustering|positive regulation of kinetochore clustering at the old mitotic spindle pole body http://purl.obolibrary.org/obo/GO_1905113 CHEBI:31915 biolink:ChemicalSubstance nogalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31915 GO:1905103 biolink:CellularComponent integral component of lysosomal membrane The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to lysosomal membrane|integral component of lysosome membrane http://purl.obolibrary.org/obo/GO_1905103 CHEBI:16319 biolink:ChemicalSubstance 2-acetamido-5-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16319 GO:1905104 biolink:BiologicalProcess obsolete response to ouabain OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905104 GO:1905105 biolink:BiologicalProcess obsolete cellular response to ouabain OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905105 CHEBI:16317 biolink:ChemicalSubstance 3alpha-hydroxyglycyrrhetinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16317 GO:1905106 biolink:BiologicalProcess obsolete response to Dizocilpine OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905106 CHEBI:16318 biolink:ChemicalSubstance 4-nitrocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16318 GO:1905107 biolink:BiologicalProcess obsolete cellular response to Dizocilpine OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905107 CHEBI:16315 biolink:ChemicalSubstance morphinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16315 GO:1905108 biolink:MolecularActivity guanosine binding Binding to guanosine. go-plus.json http://purl.obolibrary.org/obo/GO_1905108 GO:1905109 biolink:BiologicalProcess regulation of pulmonary blood vessel remodeling Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling. go-plus.json http://purl.obolibrary.org/obo/GO_1905109 CHEBI:16313 biolink:ChemicalSubstance D-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16313 CHEBI:16314 biolink:ChemicalSubstance N-formylmethanofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_16314 CHEBI:16311 biolink:ChemicalSubstance dCTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16311 CHEBI:16312 biolink:ChemicalSubstance 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16312 CHEBI:16310 biolink:ChemicalSubstance sulcatone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16310 chebi_ph7_3 NCBITaxon:2683659 biolink:OrganismalEntity Chytridiomycota incertae sedis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2683659 UBERON:0018154 biolink:AnatomicalEntity ligament of middle ear A ligament that is part of a middle ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018154 UBERON:0018151 biolink:AnatomicalEntity skin of upper lip A zone of skin that is part of a upper lip. go-plus.json upper lip skin http://purl.obolibrary.org/obo/UBERON_0018151 GO:1905120 biolink:BiologicalProcess cellular response to haloperidol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905120 gocheck_do_not_manually_annotate GO:1905121 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905121 CHEBI:31923 biolink:ChemicalSubstance novobiocic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31923 GO:1905122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905122 GO:1905123 biolink:BiologicalProcess regulation of glucosylceramidase activity Any process that modulates the frequency, rate or extent of glucosylceramidase activity. go-plus.json regulation of glucosylsphingosine beta-glucosidase activity|regulation of beta-glucocerebrosidase activity|regulation of ceramide glucosidase activity|regulation of GCase activity|regulation of beta-D-glucocerebrosidase activity|regulation of glucocerebrosidase activity|regulation of glucosphingosine glucosylhydrolase activity|regulation of psychosine hydrolase activity|regulation of GlcCer-beta-glucosidase activity|regulation of beta-glucosylceramidase activity|regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|regulation of glucosylcerebrosidase activity|regulation of glucosylsphingosine beta-D-glucosidase activity|regulation of acid beta-glucosidase activity http://purl.obolibrary.org/obo/GO_1905123 GO:1905124 biolink:BiologicalProcess negative regulation of glucosylceramidase activity Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity. go-plus.json down regulation of glucosylceramidase activity|inhibition of glucocerebrosidase activity|inhibition of acid beta-glucosidase activity|negative regulation of GCase activity|down regulation of glucosylsphingosine beta-glucosidase activity|inhibition of glucosphingosine glucosylhydrolase activity|downregulation of beta-glucocerebrosidase activity|negative regulation of beta-D-glucocerebrosidase activity|downregulation of glucosylceramidase activity|down-regulation of beta-D-glucocerebrosidase activity|inhibition of psychosine hydrolase activity|negative regulation of glucosylsphingosine beta-D-glucosidase activity|down-regulation of glucosylsphingosine beta-D-glucosidase activity|downregulation of glucosylsphingosine beta-glucosidase activity|down regulation of beta-glucocerebrosidase activity|down regulation of ceramide glucosidase activity|inhibition of beta-glucocerebrosidase activity|negative regulation of GlcCer-beta-glucosidase activity|down-regulation of GlcCer-beta-glucosidase activity|downregulation of beta-D-glucocerebrosidase activity|down regulation of glucocerebrosidase activity|downregulation of ceramide glucosidase activity|down-regulation of glucosylceramidase activity|down-regulation of beta-glucosylceramidase activity|inhibition of glucosylsphingosine beta-D-glucosidase activity|negative regulation of beta-glucosylceramidase activity|down-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|negative regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|down-regulation of glucosylsphingosine beta-glucosidase activity|down-regulation of glucosylcerebrosidase activity|negative regulation of glucosylsphingosine beta-glucosidase activity|negative regulation of glucosylcerebrosidase activity|down regulation of glucosphingosine glucosylhydrolase activity|downregulation of glucocerebrosidase activity|down regulation of beta-D-glucocerebrosidase activity|down regulation of psychosine hydrolase activity|negative regulation of acid beta-glucosidase activity|down-regulation of acid beta-glucosidase activity|downregulation of GlcCer-beta-glucosidase activity|inhibition of beta-D-glucocerebrosidase activity|downregulation of glucosphingosine glucosylhydrolase activity|inhibition of glucosylceramidase activity|negative regulation of ceramide glucosidase activity|down-regulation of ceramide glucosidase activity|downregulation of psychosine hydrolase activity|down regulation of GlcCer-beta-glucosidase activity|downregulation of beta-glucosylceramidase activity|inhibition of glucosylsphingosine beta-glucosidase activity|downregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of GlcCer-beta-glucosidase activity|downregulation of glucosylcerebrosidase activity|negative regulation of glucocerebrosidase activity|down-regulation of glucocerebrosidase activity|down regulation of glucosylsphingosine beta-D-glucosidase activity|negative regulation of beta-glucocerebrosidase activity|downregulation of acid beta-glucosidase activity|down-regulation of beta-glucocerebrosidase activity|down regulation of beta-glucosylceramidase activity|down regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of beta-glucosylceramidase activity|inhibition of ceramide glucosidase activity|down regulation of glucosylcerebrosidase activity|negative regulation of glucosphingosine glucosylhydrolase activity|down-regulation of glucosphingosine glucosylhydrolase activity|downregulation of glucosylsphingosine beta-D-glucosidase activity|inhibition of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of glucosylcerebrosidase activity|down regulation of acid beta-glucosidase activity|down-regulation of psychosine hydrolase activity|negative regulation of psychosine hydrolase activity http://purl.obolibrary.org/obo/GO_1905124 GO:1905114 biolink:BiologicalProcess cell surface receptor signaling pathway involved in cell-cell signaling Any cell surface receptor signaling pathway that is involved in cell-cell signaling. go-plus.json cell surface receptor linked signal transduction involved in cell-cell signaling|cell surface receptor linked signaling pathway involved in cell-cell signalling|cell surface receptor signaling pathway involved in cell-cell signalling|cell surface receptor linked signalling pathway involved in cell-cell signaling|cell surface receptor linked signalling pathway involved in cell-cell signalling|cell surface receptor linked signaling pathway involved in cell-cell signaling|cell surface receptor linked signal transduction involved in cell-cell signalling http://purl.obolibrary.org/obo/GO_1905114 CHEBI:16308 biolink:ChemicalSubstance sucrose 6(F)-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16308 GO:1905115 biolink:BiologicalProcess regulation of lateral attachment of mitotic spindle microtubules to kinetochore Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore. go-plus.json http://purl.obolibrary.org/obo/GO_1905115 CHEBI:16309 biolink:ChemicalSubstance 4-sulfobenzoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16309 GO:1905116 biolink:BiologicalProcess positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore. go-plus.json up regulation of lateral attachment of mitotic spindle microtubules to kinetochore|activation of lateral attachment of mitotic spindle microtubules to kinetochore|up-regulation of lateral attachment of mitotic spindle microtubules to kinetochore|upregulation of lateral attachment of mitotic spindle microtubules to kinetochore http://purl.obolibrary.org/obo/GO_1905116 GO:1905117 biolink:BiologicalProcess regulation of ribonucleoside-diphosphate reductase activity Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity. go-plus.json regulation of class I ribonucleotide reductase activity|regulation of class III ribonucleotide reductase activity|regulation of class II ribonucleoside-diphosphate reductase activity|regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|regulation of ribonucleotide reductase activity|regulation of RNR|regulation of purine/pyrimidine nucleoside diphosphate reduction|regulation of ribonucleoside 5'-diphosphate reductase activity|regulation of class II ribonucleotide reductase activity|regulation of ribonucleotide diphosphate reductase activity|regulation of nucleoside diphosphate reductase activity http://purl.obolibrary.org/obo/GO_1905117 CHEBI:16307 biolink:ChemicalSubstance anthocyanidin 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16307 chebi_ph7_3 GO:1905118 biolink:BiologicalProcess positive regulation of ribonucleoside-diphosphate reductase activity Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity. go-plus.json up-regulation of RNR|activation of ribonucleoside-diphosphate reductase activity|up regulation of class II ribonucleoside-diphosphate reductase activity|upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity|upregulation of class III ribonucleotide reductase activity|upregulation of class I ribonucleotide reductase activity|upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up regulation of nucleoside diphosphate reductase activity|up-regulation of purine/pyrimidine nucleoside diphosphate reduction|up-regulation of ribonucleoside 5'-diphosphate reductase activity|upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|positive regulation of nucleoside diphosphate reductase activity|up regulation of ribonucleotide diphosphate reductase activity|up-regulation of ribonucleoside-diphosphate reductase activity|up-regulation of class II ribonucleotide reductase activity|positive regulation of ribonucleotide diphosphate reductase activity|activation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of RNR|activation of nucleoside diphosphate reductase activity|activation of ribonucleoside 5'-diphosphate reductase activity|up regulation of class III ribonucleotide reductase activity|up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|up regulation of class I ribonucleotide reductase activity|upregulation of class II ribonucleoside-diphosphate reductase activity|up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|activation of ribonucleotide diphosphate reductase activity|activation of class II ribonucleotide reductase activity|positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|positive regulation of class I ribonucleotide reductase activity|positive regulation of class III ribonucleotide reductase activity|positive regulation of purine/pyrimidine nucleoside diphosphate reduction|up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|positive regulation of ribonucleoside 5'-diphosphate reductase activity|upregulation of ribonucleoside-diphosphate reductase activity|up-regulation of nucleoside diphosphate reductase activity|up regulation of purine/pyrimidine nucleoside diphosphate reduction|positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up regulation of ribonucleoside 5'-diphosphate reductase activity|activation of class I ribonucleotide reductase activity|up-regulation of ribonucleotide diphosphate reductase activity|activation of class III ribonucleotide reductase activity|positive regulation of class II ribonucleotide reductase activity|activation of adenosylcobalamin-dependent ribonucleotide reductase activity|up regulation of RNR|activation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up-regulation of class II ribonucleoside-diphosphate reductase activity|up regulation of class II ribonucleotide reductase activity|positive regulation of RNR|activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|upregulation of nucleoside diphosphate reductase activity|up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|up-regulation of class I ribonucleotide reductase activity|up-regulation of class III ribonucleotide reductase activity|up regulation of ribonucleoside-diphosphate reductase activity|up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|activation of RNR|activation of class II ribonucleoside-diphosphate reductase activity|upregulation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of ribonucleotide diphosphate reductase activity|upregulation of ribonucleoside 5'-diphosphate reductase activity|up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|upregulation of class II ribonucleotide reductase activity|positive regulation of class II ribonucleoside-diphosphate reductase activity http://purl.obolibrary.org/obo/GO_1905118 CHEBI:16304 biolink:ChemicalSubstance cob(II)alamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16304 chebi_ph7_3 GO:1905119 biolink:BiologicalProcess response to haloperidol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905119 gocheck_do_not_manually_annotate CHEBI:16305 biolink:ChemicalSubstance N(2),N(5)-dibenzoyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16305 CHEBI:16302 biolink:ChemicalSubstance 11-cis-retinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16302 chebi_ph7_3 CHEBI:16303 biolink:ChemicalSubstance 3-amino-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16303 CHEBI:16300 biolink:ChemicalSubstance alpha-D-ribose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16300 UBERON:0018150 biolink:AnatomicalEntity skin of lower lip A zone of skin that is part of a lower lip. go-plus.json lower lip skin http://purl.obolibrary.org/obo/UBERON_0018150 CHEBI:16301 biolink:ChemicalSubstance nitrite go-plus.json http://purl.obolibrary.org/obo/CHEBI_16301 chebi_ph7_3 GO:0031902 biolink:CellularComponent late endosome membrane The lipid bilayer surrounding a late endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0031902 GO:0006946 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006946 GO:0031903 biolink:CellularComponent microbody membrane The lipid bilayer surrounding a microbody. go-plus.json http://purl.obolibrary.org/obo/GO_0031903 GO:0006947 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006947 GO:0031900 biolink:CellularComponent chromoplast outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0031900 GO:0006944 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006944 GO:0031901 biolink:CellularComponent early endosome membrane The lipid bilayer surrounding an early endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0031901 GO:0006945 biolink:BiologicalProcess obsolete nuclear fusion during karyogamy OBSOLETE. The fusion of two haploid nuclei to form a single diploid nucleus, as seen in the yeast mating process. go-plus.json nuclear fusion during karyogamy http://purl.obolibrary.org/obo/GO_0006945 GO:0006942 biolink:BiologicalProcess regulation of striated muscle contraction Any process that modulates the frequency, rate or extent of striated muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0006942 GO:0006943 biolink:BiologicalProcess obsolete chemi-mechanical coupling OBSOLETE. The conversion of chemical energy into mechanical work (as in the contraction of a muscle). go-plus.json chemi-mechanical coupling|mechanochemical coupling http://purl.obolibrary.org/obo/GO_0006943 GO:0006940 biolink:BiologicalProcess regulation of smooth muscle contraction Any process that modulates the frequency, rate or extent of smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0006940 GO:0006941 biolink:BiologicalProcess striated muscle contraction A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. go-plus.json sarcomeric muscle contraction http://purl.obolibrary.org/obo/GO_0006941 GO:2000588 biolink:BiologicalProcess positive regulation of platelet-derived growth factor receptor-beta signaling pathway Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway. go-plus.json positive regulation of PDGF receptor-beta signaling pathway|positive regulation of platelet-derived growth factor receptor-beta signalling pathway|positive regulation of betaPDGF receptor signaling pathway|positive regulation of PDGFR-beta signaling pathway http://purl.obolibrary.org/obo/GO_2000588 CHEBI:65234 biolink:ChemicalSubstance amidoxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_65234 GO:2000589 biolink:BiologicalProcess regulation of metanephric mesenchymal cell migration Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration. go-plus.json regulation of metanephric mesenchyme chemotaxis http://purl.obolibrary.org/obo/GO_2000589 GO:0031908 biolink:CellularComponent glyoxysomal lumen The volume enclosed by the membranes of a glyoxysome. go-plus.json http://purl.obolibrary.org/obo/GO_0031908 GO:0031909 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031909 GO:0031906 biolink:CellularComponent late endosome lumen The volume enclosed by the membrane of a late endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0031906 GO:0031907 biolink:CellularComponent microbody lumen The volume enclosed by the membranes of a microbody. go-plus.json http://purl.obolibrary.org/obo/GO_0031907 GO:0031904 biolink:CellularComponent endosome lumen The volume enclosed by the membrane of an endosome. NIF_Subcellular:sao1547508851 go-plus.json http://purl.obolibrary.org/obo/GO_0031904 CHEBI:65232 biolink:ChemicalSubstance EC 3.4.21.5 (thrombin) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_65232 GO:0031905 biolink:CellularComponent early endosome lumen The volume enclosed by the membrane of an early endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0031905 GO:2000580 biolink:BiologicalProcess obsolete regulation of microtubule motor activity, plus-end-directed OBSOLETE. Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed. go-plus.json regulation of ATP-dependent microtubule motor activity, plus-end-directed|regulation of plus-end-directed microtubule motor activity|regulation of kinesin activity|regulation of plus-end-directed kinesin ATPase activity|regulation of kinesin ATP phosphohydrolase (plus-end-directed) http://purl.obolibrary.org/obo/GO_2000580 GO:2000581 biolink:BiologicalProcess obsolete negative regulation of microtubule motor activity, plus-end-directed OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed. go-plus.json negative regulation of plus-end-directed microtubule motor activity|negative regulation of plus-end-directed kinesin ATPase activity|negative regulation of kinesin activity|negative regulation of ATP-dependent microtubule motor activity, plus-end-directed|negative regulation of kinesin ATP phosphohydrolase (plus-end-directed) http://purl.obolibrary.org/obo/GO_2000581 GO:2000582 biolink:BiologicalProcess obsolete positive regulation of microtubule motor activity, plus-end-directed OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed. go-plus.json positive regulation of plus-end-directed kinesin ATPase activity|positive regulation of plus-end-directed microtubule motor activity|positive regulation of ATP-dependent microtubule motor activity, plus-end-directed|positive regulation of kinesin activity|positive regulation of kinesin ATP phosphohydrolase (plus-end-directed) http://purl.obolibrary.org/obo/GO_2000582 UBERON:0008867 biolink:AnatomicalEntity trabecular network of bone The network of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force go-plus.json bone trabecula|bone trabeculae http://purl.obolibrary.org/obo/UBERON_0008867 GO:2000583 biolink:BiologicalProcess regulation of platelet-derived growth factor receptor-alpha signaling pathway Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway. go-plus.json regulation of PDGF receptor-alpha signaling pathway|regulation of platelet-derived growth factor receptor-alpha signalling pathway|regulation of alphaPDGF receptor signaling pathway|regulation of PDGFR-alpha signaling pathway http://purl.obolibrary.org/obo/GO_2000583 GO:2000584 biolink:BiologicalProcess negative regulation of platelet-derived growth factor receptor-alpha signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway. go-plus.json negative regulation of platelet-derived growth factor receptor-alpha signalling pathway|negative regulation of alphaPDGF receptor signaling pathway|negative regulation of PDGF receptor-alpha signaling pathway|negative regulation of PDGFR-alpha signaling pathway http://purl.obolibrary.org/obo/GO_2000584 GO:2000585 biolink:BiologicalProcess positive regulation of platelet-derived growth factor receptor-alpha signaling pathway Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway. go-plus.json positive regulation of platelet-derived growth factor receptor-alpha signalling pathway|positive regulation of alphaPDGF receptor signaling pathway|positive regulation of PDGF receptor-alpha signaling pathway|positive regulation of PDGFR-alpha signaling pathway http://purl.obolibrary.org/obo/GO_2000585 GO:2000586 biolink:BiologicalProcess regulation of platelet-derived growth factor receptor-beta signaling pathway Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway. go-plus.json regulation of platelet-derived growth factor receptor-beta signalling pathway|regulation of PDGF receptor-beta signaling pathway|regulation of betaPDGF receptor signaling pathway|regulation of PDGFR-beta signaling pathway http://purl.obolibrary.org/obo/GO_2000586 UBERON:6025991 biolink:AnatomicalEntity insect anterior ectoderm derivative . go-plus.json http://purl.obolibrary.org/obo/UBERON_6025991 GO:2000587 biolink:BiologicalProcess negative regulation of platelet-derived growth factor receptor-beta signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway. go-plus.json negative regulation of platelet-derived growth factor receptor-beta signalling pathway|negative regulation of PDGFR-beta signaling pathway|negative regulation of betaPDGF receptor signaling pathway|negative regulation of PDGF receptor-beta signaling pathway http://purl.obolibrary.org/obo/GO_2000587 CHEBI:16298 biolink:ChemicalSubstance D-mannitol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16298 CHEBI:16299 biolink:ChemicalSubstance dehydrocoformycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16299 NCBITaxon:147389 biolink:OrganismalEntity Triticeae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147389 CHEBI:16296 biolink:ChemicalSubstance D-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_16296 UBERON:0008861 biolink:AnatomicalEntity pyloric gastric gland The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]. go-plus.json glandula pylorica|pyloric mucuous gland|pyloric antrum gland|pyloric gland http://purl.obolibrary.org/obo/UBERON_0008861 CHEBI:16297 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16297 chebi_ph7_3 CHEBI:16294 biolink:ChemicalSubstance barbituric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16294 GO:0006948 biolink:BiologicalProcess induction by virus of host cell-cell fusion The process of syncytia-forming cell-cell fusion, caused by a virus. go-plus.json viral-induced membrane fusion|viral-induced host cell-cell fusion|induction by virus of cell-cell fusion in host|viral-induced cell-cell fusion http://purl.obolibrary.org/obo/GO_0006948 GO:0006949 biolink:BiologicalProcess syncytium formation The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0006949 goslim_pir CHEBI:16295 biolink:ChemicalSubstance alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3')-1-alkyl-2-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16295 chebi_ph7_3 GO:0006957 biolink:BiologicalProcess complement activation, alternative pathway Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. go-plus.json complement cascade, alternative pathway http://purl.obolibrary.org/obo/GO_0006957 CHEBI:16292 biolink:ChemicalSubstance D-arabinono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16292 chebi_ph7_3 GO:0006958 biolink:BiologicalProcess complement activation, classical pathway Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. go-plus.json complement cascade, classical pathway http://purl.obolibrary.org/obo/GO_0006958 GO:0006955 biolink:BiologicalProcess immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. go-plus.json http://purl.obolibrary.org/obo/GO_0006955 goslim_drosophila CHEBI:16290 biolink:ChemicalSubstance 5alpha-cholesta-7,24-dien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16290 chebi_ph7_3 NCBITaxon:147380 biolink:OrganismalEntity Oryzeae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147380 GO:0006956 biolink:BiologicalProcess complement activation Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. go-plus.json complement cascade|complement activity|complement response http://purl.obolibrary.org/obo/GO_0006956 CHEBI:65240 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65240 CHEBI:16291 biolink:ChemicalSubstance 1-alkyl-2-acetyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16291 chebi_ph7_3 GO:0006953 biolink:BiologicalProcess acute-phase response An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. go-plus.json http://purl.obolibrary.org/obo/GO_0006953 GO:0006954 biolink:BiologicalProcess inflammatory response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. Wikipedia:Inflammation go-plus.json inflammation http://purl.obolibrary.org/obo/GO_0006954 GO:0006951 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006951 GO:0006952 biolink:BiologicalProcess defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. go-plus.json defense/immunity protein activity|antimicrobial peptide activity|defence response|physiological defense response http://purl.obolibrary.org/obo/GO_0006952 NCBITaxon:147385 biolink:OrganismalEntity Brachypodieae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147385 GO:2000599 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000599 GO:0006950 biolink:BiologicalProcess response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json response to biotic stress|response to abiotic stress http://purl.obolibrary.org/obo/GO_0006950 gocheck_do_not_manually_annotate|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_candida CHEBI:65248 biolink:ChemicalSubstance L-tyrosiniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_65248 chebi_ph7_3 CHEBI:41253 biolink:ChemicalSubstance tetradecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_41253 chebi_ph7_3 CHEBI:65243 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_65243 GO:2000591 biolink:BiologicalProcess positive regulation of metanephric mesenchymal cell migration Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration. go-plus.json positive regulation of metanephric mesenchyme chemotaxis http://purl.obolibrary.org/obo/GO_2000591 GO:2000592 biolink:BiologicalProcess regulation of metanephric DCT cell differentiation Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation. go-plus.json regulation of metanephric distal convoluted tubule cell differentiation http://purl.obolibrary.org/obo/GO_2000592 GO:2000593 biolink:BiologicalProcess negative regulation of metanephric DCT cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation. go-plus.json negative regulation of metanephric distal convoluted tubule cell differentiation http://purl.obolibrary.org/obo/GO_2000593 UBERON:0008856 biolink:AnatomicalEntity stomach muscularis externa The smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines go-plus.json muscle layer of stomach|gastric muscularis|muscularis externa of stomach|tunica muscularis gastris|tunica muscularis (gaster) http://purl.obolibrary.org/obo/UBERON_0008856 GO:2000594 biolink:BiologicalProcess positive regulation of metanephric DCT cell differentiation Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation. go-plus.json positive regulation of metanephric distal convoluted tubule cell differentiation http://purl.obolibrary.org/obo/GO_2000594 GO:2000595 biolink:BiologicalProcess regulation of optic nerve formation Any process that modulates the frequency, rate or extent of optic nerve formation. go-plus.json regulation of CN II formation|regulation of CN II biosynthesis http://purl.obolibrary.org/obo/GO_2000595 CHEBI:65249 biolink:ChemicalSubstance L-lysiniumyl(2+) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_65249 chebi_ph7_3 UBERON:0008858 biolink:AnatomicalEntity pyloric canal The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter go-plus.json canalis pyloricus|canalis pyloricus http://purl.obolibrary.org/obo/UBERON_0008858 GO:2000596 biolink:BiologicalProcess negative regulation of optic nerve formation Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation. go-plus.json negative regulation of CN II biosynthesis|negative regulation of CN II formation http://purl.obolibrary.org/obo/GO_2000596 GO:2000597 biolink:BiologicalProcess positive regulation of optic nerve formation Any process that activates or increases the frequency, rate or extent of optic nerve formation. go-plus.json positive regulation of CN II biosynthesis|positive regulation of CN II formation http://purl.obolibrary.org/obo/GO_2000597 GO:2000598 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000598 CHEBI:16289 biolink:ChemicalSubstance beta-D-galactosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_16289 chebi_ph7_3 CHEBI:16287 biolink:ChemicalSubstance UDP-N-acetyl-D-mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16287 CHEBI:16288 biolink:ChemicalSubstance O-acetyl-L-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16288 CHEBI:16285 biolink:ChemicalSubstance phytanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16285 CHEBI:16286 biolink:ChemicalSubstance 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16286 chebi_ph7_3 GO:0006959 biolink:BiologicalProcess humoral immune response An immune response mediated through a body fluid. Wikipedia:Humoral_immunity go-plus.json http://purl.obolibrary.org/obo/GO_0006959 UBERON:0008851 biolink:AnatomicalEntity ectoplacental cavity closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals go-plus.json epamniotic cavity|epamniotic cavity http://purl.obolibrary.org/obo/UBERON_0008851 CHEBI:16283 biolink:ChemicalSubstance L-cystine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16283 CHEBI:16284 biolink:ChemicalSubstance dATP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16284 GO:2000590 biolink:BiologicalProcess negative regulation of metanephric mesenchymal cell migration Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration. go-plus.json negative regulation of metanephric mesenchyme chemotaxis http://purl.obolibrary.org/obo/GO_2000590 GO:0006924 biolink:BiologicalProcess activation-induced cell death of T cells A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. go-plus.json activation-induced cell death of T-lymphocytes|activation-induced cell death of T-cells|antigen-driven apoptosis|activated T cell apoptosis|activation-induced cell death of T lymphocytes|AICD http://purl.obolibrary.org/obo/GO_0006924 GO:0006925 biolink:BiologicalProcess inflammatory cell apoptotic process Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. go-plus.json programmed cell death, inflammatory cells|apoptosis of inflammatory cells|programmed cell death of inflammatory cells by apoptosis|inflammatory cell apoptosis|killing of inflammatory cells|inflammatory cell programmed cell death by apoptosis http://purl.obolibrary.org/obo/GO_0006925 GO:0006922 biolink:BiologicalProcess obsolete cleavage of lamin involved in execution phase of apoptosis OBSOLETE. The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina. go-plus.json cleavage of lamin|cleavage of lamin involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0006922 CHEBI:65250 biolink:ChemicalSubstance L-cysteiniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_65250 chebi_ph7_3 GO:0006923 biolink:BiologicalProcess obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures. go-plus.json cleavage of cytoskeletal proteins involved in apoptosis|apoptotic cleavage of cytoskeletal proteins|cleavage of cytoskeletal proteins involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0006923 NCBITaxon:147370 biolink:OrganismalEntity PACMAD clade go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147370 GO:0006920 biolink:BiologicalProcess obsolete commitment to apoptosis OBSOLETE. (Was not defined before being made obsolete). go-plus.json commitment to apoptosis http://purl.obolibrary.org/obo/GO_0006920 GO:0006921 biolink:BiologicalProcess cellular component disassembly involved in execution phase of apoptosis The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. go-plus.json cellular component disassembly involved in apoptotic process|disassembly of cell structures|cellular component disassembly involved in apoptosis http://purl.obolibrary.org/obo/GO_0006921 CHEBI:65256 biolink:ChemicalSubstance antimicrobial food preservative go-plus.json http://purl.obolibrary.org/obo/CHEBI_65256 CHEBI:65258 biolink:ChemicalSubstance L-pyrrolysinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_65258 CHEBI:65259 biolink:ChemicalSubstance GABA antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_65259 CHEBI:41241 biolink:ChemicalSubstance (R)-2-benzylsuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41241 CHEBI:65254 biolink:ChemicalSubstance LRH-1 agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_65254 CHEBI:65255 biolink:ChemicalSubstance food preservative go-plus.json http://purl.obolibrary.org/obo/CHEBI_65255 UBERON:0008845 biolink:AnatomicalEntity nonskeletal ligament A ligament that does not connect two skeletal elements. go-plus.json non-skeletal ligament|fibrous ligament http://purl.obolibrary.org/obo/UBERON_0008845 UBERON:0008846 biolink:AnatomicalEntity skeletal ligament Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]. go-plus.json articular ligament|articular larua|ligament|true ligament http://purl.obolibrary.org/obo/UBERON_0008846 CHEBI:90218 biolink:ChemicalSubstance gentamycin(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90218 chebi_ph7_3 CHEBI:90219 biolink:ChemicalSubstance gentamycin 2''-phosphate dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_90219 chebi_ph7_3 NCBITaxon:147368 biolink:OrganismalEntity Pooideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147368 NCBITaxon:147369 biolink:OrganismalEntity Panicoideae go-plus.json Centothecoideae http://purl.obolibrary.org/obo/NCBITaxon_147369 NCBITaxon:147367 biolink:OrganismalEntity Oryzoideae go-plus.json Ehrhartoideae http://purl.obolibrary.org/obo/NCBITaxon_147367 GO:0006928 biolink:BiologicalProcess movement of cell or subcellular component The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore. go-plus.json cellular component motion|cell movement|cellular component movement http://purl.obolibrary.org/obo/GO_0006928 goslim_pir|gocheck_do_not_annotate GO:0006929 biolink:BiologicalProcess substrate-dependent cell migration The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate. go-plus.json substrate-bound cell migration http://purl.obolibrary.org/obo/GO_0006929 GO:0006926 biolink:BiologicalProcess obsolete virus-infected cell apoptotic process OBSOLETE. Any apoptotic process in a cell infected with a virus. go-plus.json virus-infected cell programmed cell death by apoptosis|programmed cell death of virus-infected cells by apoptosis|programmed cell death, virus-infected cells|virus-infected cell apoptosis|killing virus-infected cells|apoptosis of virus-infected cells|virus-infected cell apoptotic process http://purl.obolibrary.org/obo/GO_0006926 GO:0006927 biolink:BiologicalProcess obsolete transformed cell apoptotic process OBSOLETE. Any apoptotic process in a transformed cell, a cell that has undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm. go-plus.json programmed cell death of transformed cells by apoptosis|transformed cell programmed cell death by apoptosis|apoptosis of transformed cells|killing transformed cells|programmed cell death, transformed cells|transformed cell apoptosis http://purl.obolibrary.org/obo/GO_0006927 GO:0006935 biolink:BiologicalProcess chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). Wikipedia:Chemotaxis go-plus.json taxis in response to chemical stimulus http://purl.obolibrary.org/obo/GO_0006935 GO:0006936 biolink:BiologicalProcess muscle contraction A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Wikipedia:Muscle_contraction go-plus.json http://purl.obolibrary.org/obo/GO_0006936 goslim_pir CHEBI:65260 biolink:ChemicalSubstance 3-hydroxyacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65260 GO:0006933 biolink:BiologicalProcess negative regulation of cell adhesion involved in substrate-bound cell migration The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction. go-plus.json substrate-bound cell migration, cell release from substrate http://purl.obolibrary.org/obo/GO_0006933 CHEBI:65261 biolink:ChemicalSubstance purine deoxyribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65261 GO:0006934 biolink:BiologicalProcess substrate-bound cell migration, adhesion receptor recycling The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions. go-plus.json http://purl.obolibrary.org/obo/GO_0006934 CHEBI:65262 biolink:ChemicalSubstance pyrimidine deoxyribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65262 GO:0006931 biolink:BiologicalProcess substrate-dependent cell migration, cell attachment to substrate The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions. go-plus.json substrate-bound cell migration, cell attachment to substrate http://purl.obolibrary.org/obo/GO_0006931 GO:0006932 biolink:BiologicalProcess substrate-dependent cell migration, cell contraction The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves. go-plus.json substrate-bound cell migration, cell contraction http://purl.obolibrary.org/obo/GO_0006932 GO:0006930 biolink:BiologicalProcess substrate-dependent cell migration, cell extension The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell. go-plus.json substrate-bound cell migration, cell extension http://purl.obolibrary.org/obo/GO_0006930 CHEBI:65263 biolink:ChemicalSubstance cyclobutadithymidine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65263 chebi_ph7_3 CHEBI:65264 biolink:ChemicalSubstance dodecanoyl-pantetheine-4-phosphorylserine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65264 chebi_ph7_3 UBERON:0008835 biolink:AnatomicalEntity hepatic diverticulum An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. go-plus.json liver diverticulum|diverticulum hepaticum http://purl.obolibrary.org/obo/UBERON_0008835 UBERON:0008836 biolink:AnatomicalEntity liver bud go-plus.json http://purl.obolibrary.org/obo/UBERON_0008836 CHEBI:41237 biolink:ChemicalSubstance benzyl benzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_41237 chebi_ph7_3 GO:0006939 biolink:BiologicalProcess smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. go-plus.json visceral muscle contraction http://purl.obolibrary.org/obo/GO_0006939 GO:0006937 biolink:BiologicalProcess regulation of muscle contraction Any process that modulates the frequency, rate or extent of muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0006937 GO:0006938 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006938 GO:0006902 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006902 GO:0006903 biolink:BiologicalProcess vesicle targeting The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. go-plus.json http://purl.obolibrary.org/obo/GO_0006903 CHEBI:16260 biolink:ChemicalSubstance 2-nitrophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16260 GO:0006900 biolink:BiologicalProcess vesicle budding from membrane The evagination of a membrane, resulting in formation of a vesicle. go-plus.json single-organism membrane budding|single organism membrane budding|vesicle budding|nonselective vesicle assembly|vesicle biosynthesis|membrane evagination|vesicle formation http://purl.obolibrary.org/obo/GO_0006900 GO:0006901 biolink:BiologicalProcess vesicle coating A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination. go-plus.json vesicle coat assembly http://purl.obolibrary.org/obo/GO_0006901 GO:2000544 biolink:BiologicalProcess regulation of endothelial cell chemotaxis to fibroblast growth factor Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_2000544 GO:2000545 biolink:BiologicalProcess negative regulation of endothelial cell chemotaxis to fibroblast growth factor Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_2000545 GO:2000546 biolink:BiologicalProcess positive regulation of endothelial cell chemotaxis to fibroblast growth factor Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_2000546 GO:2000547 biolink:BiologicalProcess regulation of dendritic cell dendrite assembly Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. go-plus.json regulation of dendritic extension http://purl.obolibrary.org/obo/GO_2000547 GO:2000548 biolink:BiologicalProcess negative regulation of dendritic cell dendrite assembly Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. go-plus.json negative regulation of dendritic extension http://purl.obolibrary.org/obo/GO_2000548 UBERON:0018227 biolink:AnatomicalEntity pulmonary lymphatic vessel A lymphatic vessel that is part of a lung. go-plus.json lymphatic vessel of lung http://purl.obolibrary.org/obo/UBERON_0018227 GO:2000549 biolink:BiologicalProcess positive regulation of dendritic cell dendrite assembly Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. go-plus.json positive regulation of dendritic extension http://purl.obolibrary.org/obo/GO_2000549 UBERON:0018226 biolink:AnatomicalEntity pulmonary part of lymphatic system An organ system subdivision that is the part of the lymphoid system that includes the pulmonary lymphatic vessels. go-plus.json pulmonary lymphatic chain|pulmonary lymphatic vasculature http://purl.obolibrary.org/obo/UBERON_0018226 GO:2000540 biolink:BiologicalProcess negative regulation of protein geranylgeranylation Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation. go-plus.json negative regulation of protein amino acid geranylgeranylation|negative regulation of C-terminal protein geranylgeranylation http://purl.obolibrary.org/obo/GO_2000540 CHEBI:90238 biolink:ChemicalSubstance beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90238 GO:2000541 biolink:BiologicalProcess positive regulation of protein geranylgeranylation Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation. go-plus.json positive regulation of C-terminal protein geranylgeranylation|positive regulation of protein amino acid geranylgeranylation http://purl.obolibrary.org/obo/GO_2000541 NCBITaxon:436489 biolink:OrganismalEntity Saurischia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_436489 NCBITaxon:436486 biolink:OrganismalEntity Dinosauria go-plus.json dinosaur|dinosaurs http://purl.obolibrary.org/obo/NCBITaxon_436486 GO:2000542 biolink:BiologicalProcess negative regulation of gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_2000542 GO:2000543 biolink:BiologicalProcess positive regulation of gastrulation Any process that activates or increases the frequency, rate or extent of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_2000543 CHEBI:16259 biolink:ChemicalSubstance N-acetyl-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16259 CL:0008046 biolink:Cell extrafusal muscle fiber A skeletal muscle fiber that is innervated by alpha motor neuron and generates tension by contracting, thereby allowing for skeletal movement. These fibers make up the large mass of skeletal muscle tissue and are attached to bones by tendons. go-plus.json myofibra extrafusalis http://purl.obolibrary.org/obo/CL_0008046 CHEBI:16256 biolink:ChemicalSubstance 2-methyl-3-oxopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16256 CHEBI:16257 biolink:ChemicalSubstance 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16257 GO:0006908 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006908 CHEBI:90236 biolink:ChemicalSubstance (2E,6E)-farnesyl monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90236 CHEBI:16254 biolink:ChemicalSubstance 11-cis-retinyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16254 chebi_ph7_3 GO:0006909 biolink:BiologicalProcess phagocytosis A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. Wikipedia:Phagocytosis go-plus.json http://purl.obolibrary.org/obo/GO_0006909 CHEBI:16255 biolink:ChemicalSubstance L-histidinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16255 CHEBI:90230 biolink:ChemicalSubstance prostaglandin E2 1-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_90230 chebi_ph7_3 CHEBI:16252 biolink:ChemicalSubstance 6-methoxymellein go-plus.json http://purl.obolibrary.org/obo/CHEBI_16252 chebi_ph7_3 GO:0006906 biolink:BiologicalProcess vesicle fusion Fusion of the membrane of a transport vesicle with its target membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0006906 GO:0006907 biolink:BiologicalProcess pinocytosis An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane. Wikipedia:Pinocytosis go-plus.json single-organism pinocytosis|clathrin-independent pinocytosis|fluid-phase endocytosis http://purl.obolibrary.org/obo/GO_0006907 CHEBI:16253 biolink:ChemicalSubstance 2-(acetamidomethylidene)succinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16253 CHEBI:90231 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90231 GO:0006904 biolink:BiologicalProcess vesicle docking involved in exocytosis The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis. go-plus.json vesicle docking during exocytosis http://purl.obolibrary.org/obo/GO_0006904 CHEBI:16250 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_16250 chebi_ph7_3 CHEBI:90233 biolink:ChemicalSubstance prostaglandin F2alpha 1-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_90233 chebi_ph7_3 CHEBI:16251 biolink:ChemicalSubstance deaminohydroxyblasticidin S go-plus.json http://purl.obolibrary.org/obo/CHEBI_16251 GO:0006905 biolink:BiologicalProcess obsolete vesicle transport OBSOLETE. (Was not defined before being made obsolete). go-plus.json vesicle transport http://purl.obolibrary.org/obo/GO_0006905 GO:0006913 biolink:BiologicalProcess nucleocytoplasmic transport The directed movement of molecules between the nucleus and the cytoplasm. go-plus.json nucleocytoplasmic shuttling http://purl.obolibrary.org/obo/GO_0006913 goslim_chembl|goslim_drosophila|goslim_generic|goslim_pombe GO:0006914 biolink:BiologicalProcess autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. Wikipedia:Autophagy_(cellular) go-plus.json http://purl.obolibrary.org/obo/GO_0006914 goslim_chembl|goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe GO:0006911 biolink:BiologicalProcess phagocytosis, engulfment The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. go-plus.json phagosome formation|phagosome biosynthesis http://purl.obolibrary.org/obo/GO_0006911 CHEBI:65283 biolink:ChemicalSubstance dodecanoyl-pantetheine-4-phosphorylserine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65283 GO:0006912 biolink:BiologicalProcess obsolete phagosome formation OBSOLETE. (Was not defined before being made obsolete). go-plus.json phagosome formation http://purl.obolibrary.org/obo/GO_0006912 GO:0006910 biolink:BiologicalProcess phagocytosis, recognition The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell. go-plus.json recognition of phagocytosed substance by phagocytic cell http://purl.obolibrary.org/obo/GO_0006910 NCBITaxon:4069 biolink:OrganismalEntity Solanales go-plus.json Solananae http://purl.obolibrary.org/obo/NCBITaxon_4069 CHEBI:65280 biolink:ChemicalSubstance N(omega)-methyl-argininium(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65280 chebi_ph7_3 GO:2000555 biolink:BiologicalProcess negative regulation of T-helper 1 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production. go-plus.json negative regulation of Th1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000555 GO:2000556 biolink:BiologicalProcess positive regulation of T-helper 1 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production. go-plus.json positive regulation of Th1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000556 GO:2000557 biolink:BiologicalProcess regulation of immunoglobulin production in mucosal tissue Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue. go-plus.json regulation of antibody production in mucosal tissue http://purl.obolibrary.org/obo/GO_2000557 GO:2000558 biolink:BiologicalProcess positive regulation of immunoglobulin production in mucosal tissue Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue. go-plus.json positive regulation of antibody production in mucosal tissue http://purl.obolibrary.org/obo/GO_2000558 GO:2000559 biolink:BiologicalProcess regulation of CD24 production Any process that modulates the frequency, rate or extent of CD24 biosynthetic process. go-plus.json regulation of CD24 formation|regulation of CD24 biosynthesis|regulation of CD24 biosynthetic process|regulation of CD24 anabolism|regulation of CD24 synthesis http://purl.obolibrary.org/obo/GO_2000559 CHEBI:65285 biolink:ChemicalSubstance aliphatic amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_65285 chebi_ph7_3 CHEBI:65286 biolink:ChemicalSubstance L-tyrosine-O-sulfate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65286 chebi_ph7_3 CHEBI:65287 biolink:ChemicalSubstance cyclobutadithymidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65287 NCBITaxon:4070 biolink:OrganismalEntity Solanaceae go-plus.json nightshade family http://purl.obolibrary.org/obo/NCBITaxon_4070 UBERON:0008897 biolink:AnatomicalEntity fin An external projection of an aquatic animal as a fish used in propelling or guiding the body[BTO]. go-plus.json fins http://purl.obolibrary.org/obo/UBERON_0008897 NCBITaxon:4071 biolink:OrganismalEntity Capsicum go-plus.json peppers http://purl.obolibrary.org/obo/NCBITaxon_4071 CHEBI:41218 biolink:ChemicalSubstance mercaptoethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_41218 chebi_ph7_3 GO:2000550 biolink:BiologicalProcess negative regulation of B cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000550 GO:2000551 biolink:BiologicalProcess regulation of T-helper 2 cell cytokine production Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production. go-plus.json regulation of Th2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000551 CHEBI:90228 biolink:ChemicalSubstance epoxypheophorbide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_90228 GO:2000552 biolink:BiologicalProcess negative regulation of T-helper 2 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production. go-plus.json negative regulation of Th2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000552 GO:2000553 biolink:BiologicalProcess positive regulation of T-helper 2 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production. go-plus.json positive regulation of Th2 cell cytokine production http://purl.obolibrary.org/obo/GO_2000553 CHEBI:16247 biolink:ChemicalSubstance phospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16247 chebi_ph7_3 OBO:chebi#is_tautomer_of biolink:OntologyClass is tautomer of go-plus.json http://purl.obolibrary.org/obo/chebi#is_tautomer_of GO:2000554 biolink:BiologicalProcess regulation of T-helper 1 cell cytokine production Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production. go-plus.json regulation of Th1 cell cytokine production http://purl.obolibrary.org/obo/GO_2000554 CHEBI:90224 biolink:ChemicalSubstance 2-methylhexanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90224 CHEBI:16246 biolink:ChemicalSubstance D-ribitol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16246 GO:0006919 biolink:BiologicalProcess activation of cysteine-type endopeptidase activity involved in apoptotic process Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. go-plus.json caspase activation|activation of metacaspase activity|activation of caspase activity http://purl.obolibrary.org/obo/GO_0006919 CHEBI:16243 biolink:ChemicalSubstance quercetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16243 CHEBI:16244 biolink:ChemicalSubstance 4-(trimethylammonio)butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16244 chebi_ph7_3 GO:0006917 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006917 CHEBI:16241 biolink:ChemicalSubstance aldehydo-D-arabinose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16241 NCBITaxon:436491 biolink:OrganismalEntity Theropoda go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_436491 GO:0006918 biolink:BiologicalProcess obsolete induction of apoptosis by p53 OBSOLETE. (Was not defined before being made obsolete). go-plus.json induction of apoptosis by p53 http://purl.obolibrary.org/obo/GO_0006918 NCBITaxon:436492 biolink:OrganismalEntity Coelurosauria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_436492 GO:0006915 biolink:BiologicalProcess apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. Wikipedia:Apoptosis go-plus.json apoptosis|type I programmed cell death|signaling (initiator) caspase activity|caspase-dependent programmed cell death|commitment to apoptosis|apoptosis signaling|apoptotic programmed cell death|apoptotic cell death|cellular suicide|cell suicide|apoptosis activator activity|induction of apoptosis|apoptotic program|programmed cell death by apoptosis|induction of apoptosis by p53|activation of apoptosis http://purl.obolibrary.org/obo/GO_0006915 UBERON:0008895 biolink:AnatomicalEntity splanchnocranium Subdivision of endoskeleton derived from pharyngeal arches go-plus.json gill arch skeleton|visceral skeleton|visceral skeletal system|pharyngeal arch|viscerocranium|branchial arch skeleton|pharyngeal skeleton|visceral cranium|pharyngeal endoskeleton|pharyngeal arch skeleton http://purl.obolibrary.org/obo/UBERON_0008895 NCBITaxon:4072 biolink:OrganismalEntity Capsicum annuum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4072 UBERON:0008896 biolink:AnatomicalEntity post-hyoid pharyngeal arch A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher. go-plus.json gill arch|branchial arches|gill bar|branchial bars|pharyngeal arch 3-7|visceral arches 3-7|branchial bar|branchial arch|gill arches 1-5 http://purl.obolibrary.org/obo/UBERON_0008896 CHEBI:90222 biolink:ChemicalSubstance (S)-2-methylbutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90222 GO:0006916 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006916 CHEBI:16240 biolink:ChemicalSubstance hydrogen peroxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16240 chebi_ph7_3 CHEBI:16281 biolink:ChemicalSubstance 3-(2-carboxyethenyl)-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16281 CHEBI:16282 biolink:ChemicalSubstance 2-ureidoglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16282 CHEBI:65294 biolink:ChemicalSubstance phosphatidylcholine 28:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_65294 chebi_ph7_3 CHEBI:65295 biolink:ChemicalSubstance N-alkylphthalic monoamide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65295 chebi_ph7_3 CL:0008030 biolink:Cell excitatory neuron go-plus.json http://purl.obolibrary.org/obo/CL_0008030 GO:2000566 biolink:BiologicalProcess positive regulation of CD8-positive, alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000566 CHEBI:89268 biolink:ChemicalSubstance 2-hydroxyestradiol 3-methyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_89268 chebi_ph7_3 GO:2000567 biolink:BiologicalProcess regulation of memory T cell activation Any process that modulates the frequency, rate or extent of memory T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000567 GO:2000568 biolink:BiologicalProcess positive regulation of memory T cell activation Any process that activates or increases the frequency, rate or extent of memory T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000568 GO:2000569 biolink:BiologicalProcess regulation of T-helper 2 cell activation Any process that modulates the frequency, rate or extent of T-helper 2 cell activation. go-plus.json regulation of Th2 cell activation http://purl.obolibrary.org/obo/GO_2000569 CHEBI:65296 biolink:ChemicalSubstance primary ammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_65296 chebi_ph7_3 UBERON:0008886 biolink:AnatomicalEntity pulmonary vascular system The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins. go-plus.json pulmonary circulatory system|pulmonary system http://purl.obolibrary.org/obo/UBERON_0008886 UBERON:0008887 biolink:AnatomicalEntity rectal venous plexus The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus. go-plus.json plexus venosus rectalis|hemorrhoidal plexus|plexus haemorrhoidalis|haemorrhoidal plexus http://purl.obolibrary.org/obo/UBERON_0008887 GO:2000560 biolink:BiologicalProcess positive regulation of CD24 production Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process. go-plus.json positive regulation of CD24 synthesis|positive regulation of CD24 biosynthesis|positive regulation of CD24 formation|positive regulation of CD24 biosynthetic process|positive regulation of CD24 anabolism http://purl.obolibrary.org/obo/GO_2000560 GO:2000561 biolink:BiologicalProcess regulation of CD4-positive, alpha-beta T cell proliferation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000561 GO:2000562 biolink:BiologicalProcess negative regulation of CD4-positive, alpha-beta T cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000562 CL:0008028 biolink:Cell visual system neuron go-plus.json http://purl.obolibrary.org/obo/CL_0008028 GO:2000563 biolink:BiologicalProcess positive regulation of CD4-positive, alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000563 CL:0008029 biolink:Cell inhibitory neuron go-plus.json http://purl.obolibrary.org/obo/CL_0008029 GO:2000564 biolink:BiologicalProcess regulation of CD8-positive, alpha-beta T cell proliferation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000564 GO:2000565 biolink:BiologicalProcess negative regulation of CD8-positive, alpha-beta T cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000565 CHEBI:16278 biolink:ChemicalSubstance 2-hydroxy-3-oxoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16278 CL:0008024 biolink:Cell pancreatic endocrine cell An endocrine cell that is part of the pancreas. go-plus.json http://purl.obolibrary.org/obo/CL_0008024 CL:0008025 biolink:Cell noradrenergic neuron A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/CL_0008025 CHEBI:16279 biolink:ChemicalSubstance 1-O-trans-cinnamoyl-beta-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16279 chebi_ph7_3 CL:0008026 biolink:Cell open tracheal system tracheocyte An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. go-plus.json http://purl.obolibrary.org/obo/CL_0008026 UBERON:0008881 biolink:AnatomicalEntity rostral migratory stream Unique telencephalic subventricular zones that extend from the lateral ventricles into the olfactory bulbs. Newly produced GABAergic interneurons migrate along the RMS and settle in the bulb. go-plus.json rostral migratory pathway|RMS http://purl.obolibrary.org/obo/UBERON_0008881 CHEBI:16277 biolink:ChemicalSubstance haloacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16277 CHEBI:16274 biolink:ChemicalSubstance 5,12-dihydroxanthommatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16274 UBERON:0008882 biolink:AnatomicalEntity spinal cord commissure The nerve fiber tracts that span the midline of the spinal cord go-plus.json http://purl.obolibrary.org/obo/UBERON_0008882 UBERON:0008883 biolink:AnatomicalEntity osteoid Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue. go-plus.json prebone|prebone tissue|osteoid tissue|pre-bone http://purl.obolibrary.org/obo/UBERON_0008883 CHEBI:16275 biolink:ChemicalSubstance all-trans-octaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16275 CL:0008021 biolink:Cell anterior lateral line ganglion neuron go-plus.json http://purl.obolibrary.org/obo/CL_0008021 UBERON:0008884 biolink:AnatomicalEntity left putamen A putamen that is part of a left cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008884 CL:0008022 biolink:Cell endocardial cushion cell A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. go-plus.json http://purl.obolibrary.org/obo/CL_0008022 UBERON:0008885 biolink:AnatomicalEntity right putamen A putamen that is part of a right cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008885 CHEBI:16273 biolink:ChemicalSubstance 2-amino-3-oxo-4-(phosphonooxy)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16273 CHEBI:16270 biolink:ChemicalSubstance benzoylagmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16270 CHEBI:16271 biolink:ChemicalSubstance 2-exo-hydroxy-1,8-cineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16271 chebi_ph7_3 CHEBI:90240 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90240 GO:2000577 biolink:BiologicalProcess obsolete regulation of microtubule motor activity, minus-end-directed OBSOLETE. Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed. go-plus.json regulation of minus-end-directed kinesin ATPase activity|regulation of kinesin ATP phosphohydrolase (minus-end-directed)|regulation of ATP-dependent microtubule motor activity, minus-end-directed|regulation of minus-end-directed microtubule motor activity http://purl.obolibrary.org/obo/GO_2000577 GO:2000578 biolink:BiologicalProcess obsolete negative regulation of microtubule motor activity, minus-end-directed OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed. go-plus.json negative regulation of ATP-dependent microtubule motor activity, minus-end-directed|negative regulation of minus-end-directed kinesin ATPase activity|negative regulation of kinesin ATP phosphohydrolase (minus-end-directed)|negative regulation of minus-end-directed microtubule motor activity http://purl.obolibrary.org/obo/GO_2000578 CHEBI:31887 biolink:ChemicalSubstance N-acetyl-L-2-aminoadipic acid 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31887 GO:2000579 biolink:BiologicalProcess obsolete positive regulation of microtubule motor activity, minus-end-directed OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed. go-plus.json positive regulation of ATP-dependent microtubule motor activity, minus-end-directed|positive regulation of kinesin ATP phosphohydrolase (minus-end-directed)|positive regulation of minus-end-directed kinesin ATPase activity|positive regulation of minus-end-directed microtubule motor activity http://purl.obolibrary.org/obo/GO_2000579 UBERON:0008876 biolink:AnatomicalEntity hypodermis skeletal muscle layer Any skeletal muscle organ in the hypodermis / superficial fascia go-plus.json hypodermis muscle layer|hypodermal muscle layer|panniculus carnosus|superficial fascia muscular layer http://purl.obolibrary.org/obo/UBERON_0008876 GO:2000570 biolink:BiologicalProcess positive regulation of T-helper 2 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation. go-plus.json positive regulation of Th2 cell activation http://purl.obolibrary.org/obo/GO_2000570 GO:2000571 biolink:BiologicalProcess regulation of interleukin-4-dependent isotype switching to IgE isotypes Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes. go-plus.json regulation of IL-4-dependent isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_2000571 GO:2000572 biolink:BiologicalProcess positive regulation of interleukin-4-dependent isotype switching to IgE isotypes Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes. go-plus.json positive regulation of IL-4-dependent isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_2000572 CL:0008039 biolink:Cell lower motor neuron The motor neurons of vertebrates that directly innervate skeletal muscles. They receive input from upper motor neurons. go-plus.json http://purl.obolibrary.org/obo/CL_0008039 GO:2000573 biolink:BiologicalProcess positive regulation of DNA biosynthetic process Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process. go-plus.json positive regulation of DNA anabolism|positive regulation of DNA synthesis|positive regulation of DNA biosynthesis|positive regulation of DNA formation http://purl.obolibrary.org/obo/GO_2000573 CHEBI:31883 biolink:ChemicalSubstance N-oleoyldopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_31883 chebi_ph7_3 GO:2000574 biolink:BiologicalProcess obsolete regulation of microtubule motor activity OBSOLETE. Any process that modulates the frequency, rate or extent of microtubule motor activity. go-plus.json regulation of dynein|regulation of kinetochore motor activity|regulation of axonemal motor activity|regulation of dynein ATPase activity|regulation of kinesin|regulation of kinesin motor activity http://purl.obolibrary.org/obo/GO_2000574 GO:2000575 biolink:BiologicalProcess obsolete negative regulation of microtubule motor activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule motor activity. go-plus.json negative regulation of dynein ATPase activity|negative regulation of kinesin|negative regulation of kinesin motor activity|negative regulation of axonemal motor activity|negative regulation of dynein|negative regulation of kinetochore motor activity http://purl.obolibrary.org/obo/GO_2000575 CHEBI:16269 biolink:ChemicalSubstance N,N-dimethylaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16269 chebi_ph7_3 GO:2000576 biolink:BiologicalProcess obsolete positive regulation of microtubule motor activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of microtubule motor activity. go-plus.json positive regulation of kinetochore motor activity|positive regulation of dynein ATPase activity|positive regulation of axonemal motor activity|positive regulation of kinesin motor activity|positive regulation of dynein|positive regulation of kinesin http://purl.obolibrary.org/obo/GO_2000576 CHEBI:31885 biolink:ChemicalSubstance N-acetyl-L-2-aminoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31885 NCBITaxon:123368 biolink:OrganismalEntity Acanthomorphata go-plus.json Acanthomorpha http://purl.obolibrary.org/obo/NCBITaxon_123368 CHEBI:16267 biolink:ChemicalSubstance (R)-4-hydroxymandelonitrile beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16267 chebi_ph7_3 CHEBI:16268 biolink:ChemicalSubstance nitroethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_16268 chebi_ph7_3 CHEBI:90246 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90246 chebi_ph7_3 NCBITaxon:123369 biolink:OrganismalEntity Euacanthomorphacea go-plus.json Euacanthomorpha http://purl.obolibrary.org/obo/NCBITaxon_123369 CHEBI:16265 biolink:ChemicalSubstance succinic semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16265 UBERON:0008870 biolink:AnatomicalEntity pulmonary alveolar parenchyma The distinguishing cell types of the lung alveolar tissue, including pulmonary epithelial cells (pneumocytes), alveolar capillary endothelial cells, interstitial cells (fibroblasts) and alveolar macrophages go-plus.json http://purl.obolibrary.org/obo/UBERON_0008870 CL:0008038 biolink:Cell alpha motor neuron A large, multipolar lower motor neuron of the brainstem and spinal cord that innervates the extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. While their cell bodies are in the CNS (in the anterior gray horn of the spinal cord), they are part of the somatic nervous system - a branch of the PNS. go-plus.json alpha motoneuron http://purl.obolibrary.org/obo/CL_0008038 CHEBI:16266 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16266 NCBITaxon:123365 biolink:OrganismalEntity Neoteleostei go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_123365 CHEBI:16264 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16264 CL:0008033 biolink:Cell decidual pericyte A pericyte of the decidual vasculature. go-plus.json decidual perivascular cell http://purl.obolibrary.org/obo/CL_0008033 NCBITaxon:123366 biolink:OrganismalEntity Eurypterygia go-plus.json Eurypterygii http://purl.obolibrary.org/obo/NCBITaxon_123366 CHEBI:16261 biolink:ChemicalSubstance chitosan go-plus.json http://purl.obolibrary.org/obo/CHEBI_16261 NCBITaxon:123367 biolink:OrganismalEntity Ctenosquamata go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_123367 UBERON:0008874 biolink:AnatomicalEntity pulmonary acinus The part of the airway consisting of a respiratory bronchiole and all of its branches go-plus.json lobulus pulmonis primarius|primary pulmonary lobule|respiratory lobule|arbor alveolaris|acinus pulmonaris http://purl.obolibrary.org/obo/UBERON_0008874 CL:0008034 biolink:Cell mural cell Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. go-plus.json http://purl.obolibrary.org/obo/CL_0008034 GO:0031988 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031988 GO:1905090 biolink:BiologicalProcess negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization. go-plus.json down regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|downregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|down-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|inhibition of parkin-mediated mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1905090 GO:0031989 biolink:BiologicalProcess bombesin receptor signaling pathway The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands. go-plus.json bombesin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031989 GO:0031986 biolink:CellularComponent proteinoplast A leucoplast in which protein is stored. Wikipedia:Proteinoplast go-plus.json http://purl.obolibrary.org/obo/GO_0031986 GO:0090282 biolink:BiologicalProcess positive regulation of transcription involved in G2/M transition of mitotic cell cycle Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle. go-plus.json up-regulation of transcription involved in G2/M transition of mitotic cell cycle|positive regulation of G2/M-specific transcription in the mitotic cell cycle|activation of G2/M-specific transcription in the mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|up-regulation of G2/M-specific transcription in the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|activation of transcription involved in G2/M transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0090282 GO:1905091 biolink:BiologicalProcess positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization. go-plus.json upregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|up regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|activation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|up-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1905091 GO:0090283 biolink:BiologicalProcess regulation of protein glycosylation in Golgi Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. go-plus.json regulation of protein amino acid glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0090283 GO:1905092 biolink:BiologicalProcess response to diosgenin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905092 GO:0031987 biolink:BiologicalProcess locomotion involved in locomotory behavior Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. go-plus.json locomotion during locomotory behaviour http://purl.obolibrary.org/obo/GO_0031987 GO:0090280 biolink:BiologicalProcess positive regulation of calcium ion import Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. go-plus.json positive regulation of transmembrane calcium influx http://purl.obolibrary.org/obo/GO_0090280 GO:0031984 biolink:CellularComponent organelle subcompartment A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle. go-plus.json suborganelle compartment http://purl.obolibrary.org/obo/GO_0031984 GO:1905093 biolink:BiologicalProcess cellular response to diosgenin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905093 GO:0031985 biolink:CellularComponent Golgi cisterna Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex. NIF_Subcellular:sao561419532 go-plus.json Golgi lamellae http://purl.obolibrary.org/obo/GO_0031985 GO:1905094 biolink:BiologicalProcess regulation of apolipoprotein A-I-mediated signaling pathway Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway. go-plus.json regulation of apolipoprotein A-I-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1905094 GO:0090281 biolink:BiologicalProcess negative regulation of calcium ion import Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. go-plus.json negative regulation of transmembrane calcium influx http://purl.obolibrary.org/obo/GO_0090281 GO:1905095 biolink:BiologicalProcess negative regulation of apolipoprotein A-I-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway. go-plus.json downregulation of apolipoprotein A-I-mediated signalling pathway|down regulation of apolipoprotein A-I-mediated signalling pathway|inhibition of apolipoprotein A-I-mediated signalling pathway|down-regulation of apolipoprotein A-I-mediated signaling pathway|inhibition of apolipoprotein A-I-mediated signaling pathway|down-regulation of apolipoprotein A-I-mediated signalling pathway|negative regulation of apolipoprotein A-I-mediated signalling pathway|down regulation of apolipoprotein A-I-mediated signaling pathway|downregulation of apolipoprotein A-I-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1905095 GO:1905096 biolink:BiologicalProcess positive regulation of apolipoprotein A-I-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway. go-plus.json up regulation of apolipoprotein A-I-mediated signaling pathway|activation of apolipoprotein A-I-mediated signaling pathway|upregulation of apolipoprotein A-I-mediated signalling pathway|up-regulation of apolipoprotein A-I-mediated signaling pathway|up-regulation of apolipoprotein A-I-mediated signalling pathway|activation of apolipoprotein A-I-mediated signalling pathway|upregulation of apolipoprotein A-I-mediated signaling pathway|positive regulation of apolipoprotein A-I-mediated signalling pathway|up regulation of apolipoprotein A-I-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1905096 GO:1905097 biolink:BiologicalProcess regulation of guanyl-nucleotide exchange factor activity Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity. go-plus.json regulation of GDS|regulation of guanyl-nucleotide release factor activity|regulation of GNRP|regulation of GEF|regulation of guanyl-nucleotide releasing factor|regulation of GDP-dissociation stimulator activity http://purl.obolibrary.org/obo/GO_1905097 GO:1905098 biolink:BiologicalProcess negative regulation of guanyl-nucleotide exchange factor activity Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity. go-plus.json down regulation of guanyl-nucleotide release factor activity|down regulation of GDS|down regulation of guanyl-nucleotide exchange factor activity|inhibition of GEF|inhibition of guanyl-nucleotide exchange factor activity|downregulation of GDS|downregulation of guanyl-nucleotide release factor activity|downregulation of GNRP|down regulation of GNRP|negative regulation of GDP-dissociation stimulator activity|down-regulation of guanyl-nucleotide releasing factor|negative regulation of guanyl-nucleotide releasing factor|down-regulation of GDP-dissociation stimulator activity|negative regulation of guanyl-nucleotide release factor activity|down-regulation of guanyl-nucleotide release factor activity|down-regulation of GDS|negative regulation of GDS|down regulation of GEF|inhibition of GNRP|downregulation of GEF|inhibition of GDS|down-regulation of guanyl-nucleotide exchange factor activity|inhibition of guanyl-nucleotide release factor activity|downregulation of guanyl-nucleotide releasing factor|downregulation of GDP-dissociation stimulator activity|down regulation of GDP-dissociation stimulator activity|down regulation of guanyl-nucleotide releasing factor|inhibition of GDP-dissociation stimulator activity|inhibition of guanyl-nucleotide releasing factor|down-regulation of GEF|negative regulation of GEF|negative regulation of GNRP|down-regulation of GNRP|downregulation of guanyl-nucleotide exchange factor activity http://purl.obolibrary.org/obo/GO_1905098 GO:1905099 biolink:BiologicalProcess positive regulation of guanyl-nucleotide exchange factor activity Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity. go-plus.json upregulation of GDS|upregulation of guanyl-nucleotide release factor activity|positive regulation of GNRP|up-regulation of GEF|upregulation of guanyl-nucleotide exchange factor activity|up regulation of GNRP|up-regulation of GDP-dissociation stimulator activity|up-regulation of guanyl-nucleotide releasing factor|activation of guanyl-nucleotide releasing factor|activation of GDP-dissociation stimulator activity|up regulation of guanyl-nucleotide release factor activity|up regulation of GDS|activation of GDS|positive regulation of GDS|activation of guanyl-nucleotide release factor activity|positive regulation of guanyl-nucleotide release factor activity|upregulation of GEF|up-regulation of guanyl-nucleotide exchange factor activity|upregulation of GNRP|activation of guanyl-nucleotide exchange factor activity|positive regulation of guanyl-nucleotide releasing factor|positive regulation of GDP-dissociation stimulator activity|up regulation of GDP-dissociation stimulator activity|up regulation of guanyl-nucleotide releasing factor|up-regulation of GDS|up-regulation of guanyl-nucleotide release factor activity|up regulation of GEF|up-regulation of GNRP|activation of GEF|positive regulation of GEF|up regulation of guanyl-nucleotide exchange factor activity|upregulation of GDP-dissociation stimulator activity|upregulation of guanyl-nucleotide releasing factor|activation of GNRP http://purl.obolibrary.org/obo/GO_1905099 GO:0016349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016349 GO:0016345 biolink:BiologicalProcess female meiotic chromosome movement towards spindle pole The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis. go-plus.json female meiotic chromosome movement to spindle pole|chromosome movement towards spindle pole during female meiosis|female meiotic chromosome movement http://purl.obolibrary.org/obo/GO_0016345 GO:0016346 biolink:BiologicalProcess male meiotic chromosome movement towards spindle pole The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis. go-plus.json male meiotic chromosome movement to spindle pole|chromosome movement towards spindle pole during male meiosis|male meiotic chromosome movement http://purl.obolibrary.org/obo/GO_0016346 GO:0016347 biolink:MolecularActivity obsolete calcium-independent cell adhesion molecule activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json calcium-independent cell adhesion molecule activity http://purl.obolibrary.org/obo/GO_0016347 GO:0016348 biolink:BiologicalProcess imaginal disc-derived leg joint morphogenesis The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0016348 GO:0090286 biolink:BiologicalProcess obsolete cytoskeletal anchoring at nuclear membrane OBSOLETE. The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090286 GO:0031982 biolink:CellularComponent vesicle Any small, fluid-filled, spherical organelle enclosed by membrane. NIF_Subcellular:sao221389602|Wikipedia:Vesicle_(biology) go-plus.json membrane-bounded vesicle|membrane-enclosed vesicle http://purl.obolibrary.org/obo/GO_0031982 goslim_pir GO:0016341 biolink:CellularComponent obsolete other collagen OBSOLETE. (Was not defined before being made obsolete). go-plus.json other collagen http://purl.obolibrary.org/obo/GO_0016341 GO:0031983 biolink:CellularComponent vesicle lumen The volume enclosed by the membrane or protein that forms a vesicle. NIF_Subcellular:sao797538226 go-plus.json http://purl.obolibrary.org/obo/GO_0031983 GO:0090287 biolink:BiologicalProcess regulation of cellular response to growth factor stimulus Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0090287 GO:0016342 biolink:CellularComponent catenin complex Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0016342 GO:0090284 biolink:BiologicalProcess positive regulation of protein glycosylation in Golgi Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. go-plus.json positive regulation of protein amino acid glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0090284 GO:0016343 biolink:MolecularActivity obsolete cytoskeletal anchoring activity OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane. go-plus.json cytoskeletal anchoring activity http://purl.obolibrary.org/obo/GO_0016343 GO:0031980 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031980 GO:0090285 biolink:BiologicalProcess negative regulation of protein glycosylation in Golgi Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. go-plus.json negative regulation of protein amino acid glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0090285 GO:0016344 biolink:BiologicalProcess meiotic chromosome movement towards spindle pole The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis. go-plus.json meiotic chromosome movement|chromosome migration to spindle pole during meiosis|chromosome movement towards spindle pole during meiosis|meiotic chromosome movement to spindle pole http://purl.obolibrary.org/obo/GO_0016344 GO:0031981 biolink:CellularComponent nuclear lumen The volume enclosed by the nuclear inner membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0031981 GO:0090288 biolink:BiologicalProcess negative regulation of cellular response to growth factor stimulus Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0090288 GO:0016340 biolink:BiologicalProcess calcium-dependent cell-matrix adhesion The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0016340 GO:0090289 biolink:BiologicalProcess regulation of osteoclast proliferation Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0090289 GO:0031979 biolink:CellularComponent plasma membrane-derived thylakoid lumen The volume enclosed by a plasma membrane-derived thylakoid. go-plus.json plasma membrane thylakoid lumen http://purl.obolibrary.org/obo/GO_0031979 GO:0090290 biolink:BiologicalProcess positive regulation of osteoclast proliferation Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0090290 GO:0031977 biolink:CellularComponent thylakoid lumen The volume enclosed by a thylakoid membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0031977 GO:0031978 biolink:CellularComponent plastid thylakoid lumen The volume enclosed by a plastid thylakoid membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0031978 GO:0031975 biolink:CellularComponent envelope A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. go-plus.json http://purl.obolibrary.org/obo/GO_0031975 GO:0090293 biolink:BiologicalProcess nitrogen catabolite regulation of transcription A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. go-plus.json regulation of transcription by nitrogen catabolites http://purl.obolibrary.org/obo/GO_0090293 GO:0031976 biolink:CellularComponent plastid thylakoid Any thylakoid within a plastid. go-plus.json http://purl.obolibrary.org/obo/GO_0031976 GO:0090294 biolink:BiologicalProcess nitrogen catabolite activation of transcription A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. go-plus.json positive regulation of transcription by nitrogen catabolites http://purl.obolibrary.org/obo/GO_0090294 GO:0090291 biolink:BiologicalProcess negative regulation of osteoclast proliferation Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0090291 GO:0031973 biolink:CellularComponent chromoplast intermembrane space The region between the inner and outer lipid bilayers of a chromoplast envelope. go-plus.json chromoplast envelope lumen http://purl.obolibrary.org/obo/GO_0031973 GO:0090292 biolink:BiologicalProcess nuclear matrix anchoring at nuclear membrane The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane. go-plus.json nucleoskeleton anchoring at nuclear membrane http://purl.obolibrary.org/obo/GO_0090292 GO:0031974 biolink:CellularComponent membrane-enclosed lumen The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. go-plus.json http://purl.obolibrary.org/obo/GO_0031974 GO:0016356 biolink:BiologicalProcess obsolete organophosphorus susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json organophosphorus susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016356 GO:0016357 biolink:BiologicalProcess obsolete pyrethroid susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json pyrethroid susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016357 GO:0016358 biolink:BiologicalProcess dendrite development The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0016358 GO:0016359 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016359 GO:0090297 biolink:BiologicalProcess positive regulation of mitochondrial DNA replication Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. go-plus.json positive regulation of mitochondrial DNA synthesis http://purl.obolibrary.org/obo/GO_0090297 GO:0016352 biolink:BiologicalProcess obsolete insecticide susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json insecticide susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016352 GO:0031971 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031971 GO:0016353 biolink:BiologicalProcess obsolete carbamate susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json carbamate susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016353 GO:0090298 biolink:BiologicalProcess negative regulation of mitochondrial DNA replication Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. go-plus.json negative regulation of mitochondrial DNA synthesis http://purl.obolibrary.org/obo/GO_0090298 GO:0031972 biolink:CellularComponent chloroplast intermembrane space The region between the inner and outer lipid bilayers of a chloroplast envelope. go-plus.json chloroplast envelope lumen http://purl.obolibrary.org/obo/GO_0031972 GO:0090295 biolink:BiologicalProcess nitrogen catabolite repression of transcription A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. go-plus.json nitrogen catabolite repression|negative regulation of transcription by nitrogen catabolites http://purl.obolibrary.org/obo/GO_0090295 GO:0016354 biolink:BiologicalProcess obsolete cyclodiene susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json cyclodiene susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016354 GO:0016355 biolink:BiologicalProcess obsolete DDT susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json DDT susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016355 GO:0090296 biolink:BiologicalProcess regulation of mitochondrial DNA replication Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. go-plus.json regulation of mitochondrial DNA synthesis http://purl.obolibrary.org/obo/GO_0090296 GO:0031970 biolink:CellularComponent organelle envelope lumen The region between the inner and outer lipid bilayers of an organelle envelope. go-plus.json organelle intermembrane space http://purl.obolibrary.org/obo/GO_0031970 GO:0090299 biolink:BiologicalProcess regulation of neural crest formation Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. go-plus.json http://purl.obolibrary.org/obo/GO_0090299 GO:0016350 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016350 GO:0016351 biolink:BiologicalProcess obsolete drug susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json drug susceptibility/resistance http://purl.obolibrary.org/obo/GO_0016351 GO:0031968 biolink:CellularComponent organelle outer membrane The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0031968 GO:0031969 biolink:CellularComponent chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. Wikipedia:Chloroplast_membrane go-plus.json http://purl.obolibrary.org/obo/GO_0031969 GO:0031966 biolink:CellularComponent mitochondrial membrane Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. NIF_Subcellular:sao1045389829 go-plus.json http://purl.obolibrary.org/obo/GO_0031966 GO:0031967 biolink:CellularComponent organelle envelope A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0031967 goslim_mouse GO:0090260 biolink:BiologicalProcess negative regulation of retinal ganglion cell axon guidance Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. go-plus.json axon growth cone collapse http://purl.obolibrary.org/obo/GO_0090260 GO:0031964 biolink:MolecularActivity beta-alanyl-histamine hydrolase activity Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine. go-plus.json carcinine hydrolase activity http://purl.obolibrary.org/obo/GO_0031964 GO:0031965 biolink:CellularComponent nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. NIF_Subcellular:sao1687101204 go-plus.json http://purl.obolibrary.org/obo/GO_0031965 GO:0090261 biolink:BiologicalProcess positive regulation of inclusion body assembly Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. go-plus.json http://purl.obolibrary.org/obo/GO_0090261 GO:0031962 biolink:MolecularActivity mineralocorticoid receptor binding Binding to a mineralocorticoid receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0031962 GO:0031963 biolink:MolecularActivity cortisol receptor activity Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function. go-plus.json http://purl.obolibrary.org/obo/GO_0031963 GO:0016327 biolink:CellularComponent apicolateral plasma membrane The apical end of the lateral plasma membrane of epithelial cells. go-plus.json apical lateral plasma membrane http://purl.obolibrary.org/obo/GO_0016327 NCBITaxon:4081 biolink:OrganismalEntity Solanum lycopersicum go-plus.json Solanum esculentum|Lycopersicon esculentum var. esculentum|Solanum lycopersicum var. humboldtii|Lycopersicon esculentum|tomato http://purl.obolibrary.org/obo/NCBITaxon_4081 GO:0016328 biolink:CellularComponent lateral plasma membrane The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells. go-plus.json http://purl.obolibrary.org/obo/GO_0016328 GO:0016329 biolink:MolecularActivity obsolete apoptosis regulator activity OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis. go-plus.json apoptosis regulator activity http://purl.obolibrary.org/obo/GO_0016329 GO:0016323 biolink:CellularComponent basolateral plasma membrane The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. go-plus.json http://purl.obolibrary.org/obo/GO_0016323 GO:0016324 biolink:CellularComponent apical plasma membrane The region of the plasma membrane located at the apical end of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0016324 GO:0016325 biolink:BiologicalProcess oocyte microtubule cytoskeleton organization Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. go-plus.json oocyte microtubule cytoskeleton organisation http://purl.obolibrary.org/obo/GO_0016325 GO:0016326 biolink:MolecularActivity obsolete kinesin motor activity OBSOLETE. The hydrolysis of ATP (and GTP) that drives the microtubular motor along microtubules. go-plus.json kinesin motor activity http://purl.obolibrary.org/obo/GO_0016326 GO:0090264 biolink:BiologicalProcess regulation of immune complex clearance by monocytes and macrophages Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages. go-plus.json http://purl.obolibrary.org/obo/GO_0090264 GO:0031960 biolink:BiologicalProcess response to corticosteroid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. go-plus.json response to corticosteroid stimulus http://purl.obolibrary.org/obo/GO_0031960 GO:0090265 biolink:BiologicalProcess positive regulation of immune complex clearance by monocytes and macrophages Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages. go-plus.json http://purl.obolibrary.org/obo/GO_0090265 GO:0016320 biolink:BiologicalProcess endoplasmic reticulum membrane fusion The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum. go-plus.json ER membrane fusion http://purl.obolibrary.org/obo/GO_0016320 GO:0031961 biolink:MolecularActivity cortisol receptor binding Binding to a cortisol receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0031961 GO:0090262 biolink:BiologicalProcess regulation of transcription-coupled nucleotide-excision repair Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0090262 GO:0016321 biolink:BiologicalProcess female meiosis chromosome segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. go-plus.json http://purl.obolibrary.org/obo/GO_0016321 GO:0090263 biolink:BiologicalProcess positive regulation of canonical Wnt signaling pathway Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json positive regulation of canonical Wnt receptor signaling pathway|positive regulation of canonical Wnt receptor signalling pathway|positive regulation of catenin import into nucleus|positive regulation of canonical Wnt-activated signaling pathway|positive regulation of catenin protein nuclear translocation|positive regulation of Wnt receptor signaling pathway through beta-catenin http://purl.obolibrary.org/obo/GO_0090263 GO:0016322 biolink:BiologicalProcess neuron remodeling The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development. go-plus.json axon pruning|neuronal remodeling http://purl.obolibrary.org/obo/GO_0016322 GO:0090268 biolink:BiologicalProcess activation of mitotic cell cycle spindle assembly checkpoint Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_0090268 NCBITaxon:4085 biolink:OrganismalEntity Nicotiana go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4085 GO:0090269 biolink:BiologicalProcess fibroblast growth factor production The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090269 gocheck_do_not_annotate GO:0090266 biolink:BiologicalProcess regulation of mitotic cell cycle spindle assembly checkpoint Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0090266 GO:0090267 biolink:BiologicalProcess positive regulation of mitotic cell cycle spindle assembly checkpoint Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0090267 GO:0031957 biolink:MolecularActivity very long-chain fatty acid-CoA ligase activity Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22. Reactome:R-HSA-5695957|Reactome:R-HSA-5696007|Reactome:R-HSA-8875077 go-plus.json very-long-chain fatty acid-CoA ligase activity|very-long-chain-fatty-acid-CoA ligase activity|very-long-chain fatty acid activation http://purl.obolibrary.org/obo/GO_0031957 GO:0031958 biolink:BiologicalProcess corticosteroid receptor signaling pathway Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor. go-plus.json corticosteroid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031958 GO:0031955 biolink:MolecularActivity short-chain fatty acid-CoA ligase activity Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6. go-plus.json short-chain fatty acid activation|short-chain fatty-acid-CoA ligase activity|short-chain-fatty-acid-CoA ligase activity http://purl.obolibrary.org/obo/GO_0031955 GO:0031956 biolink:MolecularActivity medium-chain fatty acid-CoA ligase activity Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12. EC:6.2.1.2|RHEA:48340 go-plus.json medium-chain fatty-acid-CoA ligase activity|medium-chain-fatty-acid-CoA ligase activity|medium-chain fatty acid activation http://purl.obolibrary.org/obo/GO_0031956 GO:0090271 biolink:BiologicalProcess positive regulation of fibroblast growth factor production Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090271 GO:0031953 biolink:BiologicalProcess negative regulation of protein autophosphorylation Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues. go-plus.json downregulation of protein amino acid autophosphorylation|down regulation of protein amino acid autophosphorylation|inhibition of protein amino acid autophosphorylation|negative regulation of protein amino acid autophosphorylation|down-regulation of protein amino acid autophosphorylation http://purl.obolibrary.org/obo/GO_0031953 GO:0031954 biolink:BiologicalProcess positive regulation of protein autophosphorylation Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues. go-plus.json up regulation of protein amino acid autophosphorylation|upregulation of protein amino acid autophosphorylation|positive regulation of protein amino acid autophosphorylation|stimulation of protein amino acid autophosphorylation|up-regulation of protein amino acid autophosphorylation|activation of protein amino acid autophosphorylation http://purl.obolibrary.org/obo/GO_0031954 GO:0090272 biolink:BiologicalProcess negative regulation of fibroblast growth factor production Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090272 GO:0031951 biolink:BiologicalProcess positive regulation of glucocorticoid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. go-plus.json upregulation of glucocorticoid catabolic process|stimulation of glucocorticoid catabolic process|up-regulation of glucocorticoid catabolic process|activation of glucocorticoid catabolic process|up regulation of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0031951 GO:0031952 biolink:BiologicalProcess regulation of protein autophosphorylation Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues. go-plus.json regulation of protein amino acid autophosphorylation http://purl.obolibrary.org/obo/GO_0031952 GO:0090270 biolink:BiologicalProcess regulation of fibroblast growth factor production Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0090270 GO:0031959 biolink:BiologicalProcess mineralocorticoid receptor signaling pathway Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor. go-plus.json mineralocorticoid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031959 GO:0016338 biolink:BiologicalProcess calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction. go-plus.json calcium-independent cell adhesion molecule activity http://purl.obolibrary.org/obo/GO_0016338 GO:0016339 biolink:BiologicalProcess calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction. go-plus.json calcium-dependent cell adhesion molecule activity http://purl.obolibrary.org/obo/GO_0016339 GO:0016334 biolink:BiologicalProcess establishment or maintenance of polarity of follicular epithelium Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0016334 GO:0016335 biolink:BiologicalProcess morphogenesis of larval imaginal disc epithelium The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0016335 GO:0016336 biolink:BiologicalProcess establishment or maintenance of polarity of larval imaginal disc epithelium Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0016336 GO:0016337 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016337 GO:0090275 biolink:BiologicalProcess negative regulation of somatostatin secretion Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_0090275 GO:0016330 biolink:BiologicalProcess second mitotic wave involved in compound eye morphogenesis A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia. go-plus.json second mitotic wave during compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0016330 GO:0090276 biolink:BiologicalProcess regulation of peptide hormone secretion Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. go-plus.json http://purl.obolibrary.org/obo/GO_0090276 GO:0016331 biolink:BiologicalProcess morphogenesis of embryonic epithelium The process in which the anatomical structures of embryonic epithelia are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0016331 GO:0031950 biolink:BiologicalProcess negative regulation of glucocorticoid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. go-plus.json down-regulation of glucocorticoid catabolic process|downregulation of glucocorticoid catabolic process|down regulation of glucocorticoid catabolic process|inhibition of glucocorticoid catabolic process http://purl.obolibrary.org/obo/GO_0031950 GO:0016332 biolink:BiologicalProcess establishment or maintenance of polarity of embryonic epithelium Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0016332 GO:0090273 biolink:BiologicalProcess regulation of somatostatin secretion Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_0090273 GO:0016333 biolink:BiologicalProcess morphogenesis of follicular epithelium The process in which the anatomical structures of a follicular epithelium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0016333 GO:0090274 biolink:BiologicalProcess positive regulation of somatostatin secretion Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_0090274 GO:0090279 biolink:BiologicalProcess regulation of calcium ion import Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. go-plus.json regulation of transmembrane calcium influx http://purl.obolibrary.org/obo/GO_0090279 NCBITaxon:4097 biolink:OrganismalEntity Nicotiana tabacum go-plus.json American tobacco|tobacco|common tobacco http://purl.obolibrary.org/obo/NCBITaxon_4097 CHEBI:507393 biolink:ChemicalSubstance taurine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_507393 chebi_ph7_3 GO:0090277 biolink:BiologicalProcess positive regulation of peptide hormone secretion Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. go-plus.json http://purl.obolibrary.org/obo/GO_0090277 GO:0090278 biolink:BiologicalProcess negative regulation of peptide hormone secretion Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. go-plus.json http://purl.obolibrary.org/obo/GO_0090278 GO:0031946 biolink:BiologicalProcess regulation of glucocorticoid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. go-plus.json http://purl.obolibrary.org/obo/GO_0031946 GO:0031947 biolink:BiologicalProcess negative regulation of glucocorticoid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. go-plus.json inhibition of glucocorticoid biosynthetic process|down regulation of glucocorticoid biosynthetic process|downregulation of glucocorticoid biosynthetic process|down-regulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0031947 GO:0031944 biolink:BiologicalProcess negative regulation of glucocorticoid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. go-plus.json negative regulation of glucocorticoid metabolism|downregulation of glucocorticoid metabolic process|down regulation of glucocorticoid metabolic process|inhibition of glucocorticoid metabolic process|down-regulation of glucocorticoid metabolic process http://purl.obolibrary.org/obo/GO_0031944 GO:0006988 biolink:BiologicalProcess obsolete unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor OBSOLETE. (Was not defined before being made obsolete). go-plus.json unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor http://purl.obolibrary.org/obo/GO_0006988 GO:0006989 biolink:BiologicalProcess obsolete unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase OBSOLETE. (Was not defined before being made obsolete). go-plus.json unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase http://purl.obolibrary.org/obo/GO_0006989 GO:0031945 biolink:BiologicalProcess positive regulation of glucocorticoid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. go-plus.json up regulation of glucocorticoid metabolic process|upregulation of glucocorticoid metabolic process|stimulation of glucocorticoid metabolic process|up-regulation of glucocorticoid metabolic process|activation of glucocorticoid metabolic process|positive regulation of glucocorticoid metabolism http://purl.obolibrary.org/obo/GO_0031945 GO:0006986 biolink:BiologicalProcess response to unfolded protein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. go-plus.json heat shock protein activity http://purl.obolibrary.org/obo/GO_0006986 GO:0031942 biolink:CellularComponent i-AAA complex Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases. go-plus.json http://purl.obolibrary.org/obo/GO_0031942 GO:0006987 biolink:BiologicalProcess obsolete activation of signaling protein activity involved in unfolded protein response OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response. go-plus.json unfolded protein response, activation of signalling protein kinase/endonuclease|unfolded protein response, activation of signaling protein activity|unfolded protein response, activation of signaling protein kinase/endonuclease http://purl.obolibrary.org/obo/GO_0006987 GO:0031943 biolink:BiologicalProcess regulation of glucocorticoid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. go-plus.json regulation of glucocorticoid metabolism http://purl.obolibrary.org/obo/GO_0031943 GO:0031940 biolink:BiologicalProcess obsolete positive regulation of chromatin silencing at telomere OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres. go-plus.json upregulation of chromatin silencing at telomere|positive regulation of heterochromatic silencing at telomere|up regulation of chromatin silencing at telomere|activation of chromatin silencing at telomere|stimulation of chromatin silencing at telomere|up-regulation of chromatin silencing at telomere http://purl.obolibrary.org/obo/GO_0031940 GO:0006984 biolink:BiologicalProcess ER-nucleus signaling pathway Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. go-plus.json endoplasmic reticulum-nuclear signaling pathway|ER-nuclear signaling pathway|ER to nucleus signalling pathway|ER to nucleus signaling pathway|endoplasmic reticulum to nucleus signaling pathway|ER-nuclear signalling pathway http://purl.obolibrary.org/obo/GO_0006984 GO:0006985 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006985 GO:0031941 biolink:CellularComponent filamentous actin A two-stranded helical polymer of the protein actin. Wikipedia:Actin go-plus.json F-actin http://purl.obolibrary.org/obo/GO_0031941 GO:0006982 biolink:BiologicalProcess response to lipid hydroperoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids. go-plus.json response to LHPO http://purl.obolibrary.org/obo/GO_0006982 UBERON:0008817 biolink:AnatomicalEntity thymus primordium endoderm An endoderm that is part of a thymus primordium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008817 GO:0006983 biolink:BiologicalProcess ER overload response The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB. go-plus.json endoplasmic reticulum overload response|EOR-mediated activation of NF-kappaB|positive regulation of NF-kappaB transcription factor activity by EOR|EOR|positive regulation of NF-kappaB transcription factor activity by ER overload response|ER-overload response|EOR-mediated NF-kappaB activation http://purl.obolibrary.org/obo/GO_0006983 GO:0006980 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006980 GO:0006981 biolink:BiologicalProcess obsolete activation of SoxR protein OBSOLETE. The conversion of the SoxR transcription factor to its active (oxidized) form. go-plus.json http://purl.obolibrary.org/obo/GO_0006981 GO:0016309 biolink:MolecularActivity 1-phosphatidylinositol-5-phosphate 4-kinase activity Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. EC:2.7.1.149|Reactome:R-HSA-1675776|RHEA:12280|Reactome:R-HSA-6811522|MetaCyc:2.7.1.149-RXN go-plus.json PIP4K|1-phosphatidylinositol-5-phosphate kinase|ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity|type II PIP kinase activity http://purl.obolibrary.org/obo/GO_0016309 GO:0031948 biolink:BiologicalProcess positive regulation of glucocorticoid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. go-plus.json up-regulation of glucocorticoid biosynthetic process|upregulation of glucocorticoid biosynthetic process|up regulation of glucocorticoid biosynthetic process|activation of glucocorticoid biosynthetic process|stimulation of glucocorticoid biosynthetic process http://purl.obolibrary.org/obo/GO_0031948 GO:0031949 biolink:BiologicalProcess regulation of glucocorticoid catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. go-plus.json http://purl.obolibrary.org/obo/GO_0031949 GO:0016305 biolink:MolecularActivity obsolete phosphatidylinositol 3-kinase activity, class II OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine. go-plus.json PI3KC2|phosphatidylinositol 3-kinase activity, class II http://purl.obolibrary.org/obo/GO_0016305 GO:0016306 biolink:MolecularActivity obsolete phosphatidylinositol 3-kinase activity, class III OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol. go-plus.json phosphatidylinositol 3-kinase activity, class III http://purl.obolibrary.org/obo/GO_0016306 GO:0016307 biolink:MolecularActivity phosphatidylinositol phosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate. go-plus.json phosphatidylinositol monophosphate kinase activity http://purl.obolibrary.org/obo/GO_0016307 GO:0016308 biolink:MolecularActivity 1-phosphatidylinositol-4-phosphate 5-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+). RHEA:14425|Reactome:R-HSA-3772436|Reactome:R-HSA-8868066|MetaCyc:2.7.1.68-RXN|Reactome:R-HSA-1676082|KEGG_REACTION:R03469|EC:2.7.1.68 go-plus.json PIP5K|PtdIns(4)P-5-kinase activity|diphosphoinositide kinase activity|1-phosphatidylinositol-4-phosphate kinase, class IB|1-phosphatidylinositol-4-phosphate kinase, class IA|PIP kinase activity|1-phosphatidylinositol-4-phosphate kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity|phosphatidylinositol-4-phosphate 5-kinase activity|phosphatidylinositol 4-phosphate kinase activity|type I PIP kinase activity http://purl.obolibrary.org/obo/GO_0016308 UBERON:0008823 biolink:AnatomicalEntity neural tube derived brain A brain that develops_from a neural tube. go-plus.json vertebrate brain http://purl.obolibrary.org/obo/UBERON_0008823 GO:0016301 biolink:MolecularActivity kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Reactome:R-HSA-6788855|Reactome:R-HSA-6788867 go-plus.json phosphokinase activity http://purl.obolibrary.org/obo/GO_0016301 goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast UBERON:0008824 biolink:AnatomicalEntity duct of epididymis Any duct branching of of the main epididymis duct. go-plus.json epididymis duct|epididymal duct http://purl.obolibrary.org/obo/UBERON_0008824 GO:0016302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016302 GO:0016303 biolink:MolecularActivity 1-phosphatidylinositol-3-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+). Reactome:R-HSA-1675961|EC:2.7.1.137|KEGG_REACTION:R03362|Reactome:R-HSA-1676024|Reactome:R-HSA-6798174|Reactome:R-HSA-109699|Reactome:R-HSA-1675939|RHEA:12709|Reactome:R-HSA-5672012|MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN go-plus.json ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity|type I phosphatidylinositol kinase activity|PI3-kinase activity|phosphatidylinositol 3-kinase activity, class I|Vps34p|phosphatidylinositol 3-kinase activity, class III|phosphatidylinositol 3-kinase activity, class II|type III phosphoinositide 3-kinase activity|PtdIns-3-kinase activity|1-phosphatidylinositol 3-kinase activity|PI3K|phosphatidylinositol 3-kinase, class I, catalyst activity http://purl.obolibrary.org/obo/GO_0016303 UBERON:0008826 biolink:AnatomicalEntity pulmonary surfactant a substance formed by type II alveolar cells composed of surface-active lipoprotein complex (phospholipoprotein). go-plus.json type II pneumocyte secretion|lung surfactant|alveolar surfactant http://purl.obolibrary.org/obo/UBERON_0008826 GO:0016304 biolink:MolecularActivity obsolete phosphatidylinositol 3-kinase activity, class I OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity. go-plus.json phosphatidylinositol 3-kinase activity, class I http://purl.obolibrary.org/obo/GO_0016304 GO:0016300 biolink:MolecularActivity tRNA (uracil) methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule. go-plus.json tRNA (uridine) methyltransferase activity http://purl.obolibrary.org/obo/GO_0016300 GO:0031935 biolink:BiologicalProcess obsolete regulation of chromatin silencing OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing. go-plus.json regulation of heterochromatic silencing http://purl.obolibrary.org/obo/GO_0031935 GO:0031936 biolink:BiologicalProcess obsolete negative regulation of chromatin silencing OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing. go-plus.json loss of chromatin silencing|down regulation of chromatin silencing|negative regulation of heterochromatic silencing|downregulation of chromatin silencing|down-regulation of chromatin silencing|inhibition of chromatin silencing http://purl.obolibrary.org/obo/GO_0031936 GO:0006999 biolink:BiologicalProcess nuclear pore organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore. go-plus.json nuclear pore complex organization and biogenesis|nuclear pore organization and biogenesis|nuclear pore organisation http://purl.obolibrary.org/obo/GO_0006999 GO:0031933 biolink:CellularComponent obsolete telomeric heterochromatin OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres. go-plus.json telomeric chromatin http://purl.obolibrary.org/obo/GO_0031933 GO:0031934 biolink:CellularComponent mating-type region heterochromatin Heterochromatic regions of the chromosome found at silenced mating-type loci. go-plus.json http://purl.obolibrary.org/obo/GO_0031934 GO:0006997 biolink:BiologicalProcess nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. go-plus.json nucleus organization and biogenesis|nuclear organization and biogenesis|nuclear organisation|nuclear morphology|nuclear organization http://purl.obolibrary.org/obo/GO_0006997 goslim_pir|goslim_aspergillus|goslim_drosophila|goslim_yeast|goslim_candida GO:0031931 biolink:CellularComponent TORC1 complex A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. Wikipedia:MTORC1 go-plus.json dTOR/dRaptor complex|nutrient sensitive complex|TORC 1 complex|dTORC1|mTORC1|TORC1|rapamycin and nutrient-sensitive TOR complex|TOR complex 1 http://purl.obolibrary.org/obo/GO_0031931 GO:0031932 biolink:CellularComponent TORC2 complex A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. Wikipedia:MTORC1 go-plus.json rapamycin and nutrient-insensitive TOR complex|TORC 2 complex|mTORC2|TORC2|TOR complex 2 http://purl.obolibrary.org/obo/GO_0031932 GO:0006998 biolink:BiologicalProcess nuclear envelope organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. go-plus.json nuclear envelope organization and biogenesis|nuclear envelope organisation http://purl.obolibrary.org/obo/GO_0006998 GO:0006995 biolink:BiologicalProcess cellular response to nitrogen starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0006995 GO:0006996 biolink:BiologicalProcess organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. go-plus.json single-organism organelle organization|organelle organization and biogenesis|organelle organisation|single organism organelle organization http://purl.obolibrary.org/obo/GO_0006996 goslim_pir|goslim_aspergillus|goslim_candida GO:0031930 biolink:BiologicalProcess mitochondria-nucleus signaling pathway A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function. go-plus.json mitochondria-nucleus signal transduction|mitochondrial signaling pathway|retrograde response|mitochondrial signalling pathway http://purl.obolibrary.org/obo/GO_0031930 GO:0006993 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006993 GO:0006994 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006994 GO:0006991 biolink:BiologicalProcess response to sterol depletion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json sterol depletion response http://purl.obolibrary.org/obo/GO_0006991 GO:0006992 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006992 GO:0031939 biolink:BiologicalProcess obsolete negative regulation of chromatin silencing at telomere OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres. go-plus.json negative regulation of heterochromatic silencing at telomere|downregulation of chromatin silencing at telomere|down-regulation of chromatin silencing at telomere|inhibition of chromatin silencing at telomere|down regulation of chromatin silencing at telomere http://purl.obolibrary.org/obo/GO_0031939 GO:0006990 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response. go-plus.json unfolded protein response, activation of target gene transcription|unfolded protein response, target gene transcriptional activation|positive regulation of transcription of target genes involved in unfolded protein response|unfolded protein response, positive regulation of target gene transcription|unfolded protein response, up regulation of target gene transcription|unfolded protein response, stimulation of target gene transcription|unfolded protein response, upregulation of target gene transcription|unfolded protein response, up-regulation of target gene transcription http://purl.obolibrary.org/obo/GO_0006990 GO:0031937 biolink:BiologicalProcess obsolete positive regulation of chromatin silencing OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing. go-plus.json upregulation of chromatin silencing|positive regulation of heterochromatic silencing|up regulation of chromatin silencing|activation of chromatin silencing|stimulation of chromatin silencing|up-regulation of chromatin silencing http://purl.obolibrary.org/obo/GO_0031937 GO:0031938 biolink:BiologicalProcess obsolete regulation of chromatin silencing at telomere OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing at telomeres. go-plus.json regulation of heterochromatic silencing at telomere http://purl.obolibrary.org/obo/GO_0031938 GO:0016316 biolink:MolecularActivity phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. Reactome:R-HSA-1676162|Reactome:R-HSA-1676164|EC:3.1.3.66|MetaCyc:3.1.3.66-RXN go-plus.json inositol polyphosphate 4-phosphatase type II activity|1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0016316 UBERON:0008810 biolink:AnatomicalEntity nasopalatine nerve A branch of that maxillary nerve that innervates the mucous membrane of the hard palate. go-plus.json nasopalatine nerves|nasopalatine|nervus nasopalatinus|naso-palatine nerve|Scarpa's nerve http://purl.obolibrary.org/obo/UBERON_0008810 GO:0016318 biolink:BiologicalProcess ommatidial rotation The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0016318 UBERON:0008811 biolink:AnatomicalEntity intromittent organ An external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]. go-plus.json copulatory organ|aedeagus|penis http://purl.obolibrary.org/obo/UBERON_0008811 GO:0016319 biolink:BiologicalProcess mushroom body development The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells. go-plus.json http://purl.obolibrary.org/obo/GO_0016319 GO:0016312 biolink:MolecularActivity inositol bisphosphate phosphatase activity Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate. Reactome:R-HSA-6809561|RHEA:57840|Reactome:R-HSA-6809565 go-plus.json http://purl.obolibrary.org/obo/GO_0016312 UBERON:0008814 biolink:AnatomicalEntity pharyngeal arch system A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]. go-plus.json pharyngeal arch region|embryonic pharyngeal complex|pharyngeal arch complex|pharyngeal complex|pharyngeal arches and clefts|pharyngeal apparatus|pharyngeal system http://purl.obolibrary.org/obo/UBERON_0008814 GO:0016313 biolink:MolecularActivity obsolete inositol-1,4,5-trisphosphate phosphatase OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate. go-plus.json inositol-1,4,5-trisphosphate phosphatase http://purl.obolibrary.org/obo/GO_0016313 GO:0016314 biolink:MolecularActivity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate. Reactome:R-HSA-199456|Reactome:R-HSA-2317387|EC:3.1.3.67|RHEA:25017|MetaCyc:3.1.3.67-RXN|Reactome:R-HSA-202237 go-plus.json PI(3,4,5)P3 3-phosphatase activity|1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity|PtdIns(3,4,5)P3 3-phosphatase activity|MMAC1|PI(3)P 3-phosphatase activity|phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0016314 CHEBI:65207 biolink:ChemicalSubstance vascular endothelial growth factor receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_65207 UBERON:0008816 biolink:AnatomicalEntity embryonic head A head that is part of a embryo. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008816 GO:0016315 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016315 CHEBI:5417 biolink:ChemicalSubstance glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_5417 GO:0016310 biolink:BiologicalProcess phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. Wikipedia:Phosphorylation go-plus.json http://purl.obolibrary.org/obo/GO_0016310 goslim_chembl|goslim_metagenomics GO:0016311 biolink:BiologicalProcess dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. Wikipedia:Dephosphorylation go-plus.json http://purl.obolibrary.org/obo/GO_0016311 CHEBI:5411 biolink:ChemicalSubstance gluconapin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_5411 chebi_ph7_3 GO:0006968 biolink:BiologicalProcess cellular defense response A defense response that is mediated by cells. go-plus.json intracellular defense response|intracellular defence response|cellular defence response http://purl.obolibrary.org/obo/GO_0006968 GO:0031924 biolink:MolecularActivity vitamin B6 transmembrane transporter activity Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other. go-plus.json vitamin B6 transporter activity http://purl.obolibrary.org/obo/GO_0031924 GO:0031925 biolink:MolecularActivity pyridoxal transmembrane transporter activity Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json pyridoxal transporter activity http://purl.obolibrary.org/obo/GO_0031925 GO:0006969 biolink:BiologicalProcess obsolete melanotic tumor response OBSOLETE. (Was not defined before being made obsolete). go-plus.json melanotic tumor response|melanotic mass response http://purl.obolibrary.org/obo/GO_0006969 GO:0006966 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006966 GO:0031922 biolink:BiologicalProcess pyridoxamine transport The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0031922 GO:0006967 biolink:BiologicalProcess positive regulation of antifungal peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis. go-plus.json antifungal polypeptide induction|upregulation of antifungal peptide biosynthetic process|up regulation of antifungal peptide biosynthetic process|activation of antifungal peptide biosynthetic process|stimulation of antifungal peptide biosynthetic process|antifungal peptide induction|up-regulation of antifungal peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0006967 GO:0031923 biolink:BiologicalProcess pyridoxine transport The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0031923 GO:0006964 biolink:BiologicalProcess positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. go-plus.json up regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|anti-Gram-negative bacterial polypeptide induction|upregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|stimulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|anti-Gram-negative bacterial peptide induction http://purl.obolibrary.org/obo/GO_0006964 GO:0031920 biolink:BiologicalProcess pyridoxal transport The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0031920 GO:0031921 biolink:BiologicalProcess pyridoxal phosphate transport The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0031921 GO:0006965 biolink:BiologicalProcess positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. go-plus.json up regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|upregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial peptide induction|stimulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial polypeptide induction http://purl.obolibrary.org/obo/GO_0006965 GO:0006962 biolink:BiologicalProcess male-specific antibacterial humoral response An immune response against bacteria, specific to males and mediated through a body fluid. go-plus.json http://purl.obolibrary.org/obo/GO_0006962 GO:0006963 biolink:BiologicalProcess positive regulation of antibacterial peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis. go-plus.json antibacterial polypeptide induction|upregulation of antibacterial peptide biosynthetic process|stimulation of antibacterial peptide biosynthetic process|activation of antibacterial peptide biosynthetic process|up-regulation of antibacterial peptide biosynthetic process|antibacterial peptide induction|up regulation of antibacterial peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0006963 GO:0006960 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006960 CHEBI:65212 biolink:ChemicalSubstance polysaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_65212 CHEBI:65213 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_65213 chebi_ph7_3 GO:0006961 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006961 CHEBI:65214 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65214 chebi_ph7_3 CHEBI:65215 biolink:ChemicalSubstance 1-acyl-2-alkyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65215 chebi_ph7_3 GO:0031928 biolink:MolecularActivity pyridoxine transmembrane transporter activity Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json pyridoxine transporter activity http://purl.obolibrary.org/obo/GO_0031928 GO:0031929 biolink:BiologicalProcess TOR signaling A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors. go-plus.json target of rapamycin signaling pathway|target of rapamycin signalling pathway|TOR signal transduction|TOR signaling pathway|TOR signaling cascade|TOR signalling pathway http://purl.obolibrary.org/obo/GO_0031929 GO:0031926 biolink:MolecularActivity pyridoxal phosphate transmembrane transporter activity Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0031926 CHEBI:65210 biolink:ChemicalSubstance (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65210 GO:0031927 biolink:MolecularActivity pyridoxamine transmembrane transporter activity Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0031927 CHEBI:65211 biolink:ChemicalSubstance 1,2-dilauroyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65211 chebi_ph7_3 UBERON:0008805 biolink:AnatomicalEntity gingival groove The gingival sulcus is an area of potential space between a tooth and the surrounding gingival tissue and is lined by sulcular epithelium. The depth of the sulcus (Latin for groove) is bounded by two entities: apically by the gingival fibers of the connective tissue attachment and coronally by the free gingival margin. go-plus.json tooth-gingiva interface|sulcus gingivalis|gingival sulcus|sulcus gingivalis http://purl.obolibrary.org/obo/UBERON_0008805 GO:0031913 biolink:CellularComponent contractile vacuole pore Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium. go-plus.json http://purl.obolibrary.org/obo/GO_0031913 GO:0006979 biolink:BiologicalProcess response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0006979 goslim_yeast GO:0031914 biolink:BiologicalProcess negative regulation of synaptic plasticity A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. go-plus.json down-regulation of synaptic plasticity|inhibition of synaptic plasticity|down regulation of synaptic plasticity|downregulation of synaptic plasticity http://purl.obolibrary.org/obo/GO_0031914 GO:0006977 biolink:BiologicalProcess DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle. go-plus.json positive regulation of cell cycle arrest by p53-mediated DNA damage response http://purl.obolibrary.org/obo/GO_0006977 GO:0031911 biolink:CellularComponent cytoproct Stable, specialized structure for extrusion of waste by the cell into the surrounding medium. go-plus.json http://purl.obolibrary.org/obo/GO_0031911 GO:0031912 biolink:CellularComponent oral apparatus Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems. go-plus.json http://purl.obolibrary.org/obo/GO_0031912 GO:0006978 biolink:BiologicalProcess DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_0006978 GO:0006975 biolink:BiologicalProcess DNA damage induced protein phosphorylation The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_0006975 GO:0031910 biolink:CellularComponent cytostome Stable, specialized structure for the ingestion of food by the cell into phagosomes. Wikipedia:Cytostome go-plus.json http://purl.obolibrary.org/obo/GO_0031910 GO:0006976 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006976 GO:0006973 biolink:BiologicalProcess intracellular accumulation of glycerol The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment. go-plus.json http://purl.obolibrary.org/obo/GO_0006973 GO:0006974 biolink:BiologicalProcess cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. go-plus.json DNA damage response|response to genotoxic stress|cellular DNA damage response|response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_0006974 goslim_yeast GO:0006971 biolink:BiologicalProcess hypotonic response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell. go-plus.json hypo-osmotic response http://purl.obolibrary.org/obo/GO_0006971 GO:0006972 biolink:BiologicalProcess hyperosmotic response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. go-plus.json HOG response|hypertonic response|response to hypertonicity http://purl.obolibrary.org/obo/GO_0006972 GO:0031919 biolink:BiologicalProcess vitamin B6 transport The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0031919 GO:0006970 biolink:BiologicalProcess response to osmotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json osmotic response|osmotic stress response http://purl.obolibrary.org/obo/GO_0006970 goslim_yeast GO:0031917 biolink:BiologicalProcess negative regulation of synaptic metaplasticity A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require. go-plus.json inhibition of synaptic metaplasticity|down regulation of synaptic metaplasticity|downregulation of synaptic metaplasticity|down-regulation of synaptic metaplasticity http://purl.obolibrary.org/obo/GO_0031917 GO:0031918 biolink:BiologicalProcess positive regulation of synaptic metaplasticity A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require. go-plus.json up-regulation of synaptic metaplasticity|upregulation of synaptic metaplasticity|up regulation of synaptic metaplasticity|activation of synaptic metaplasticity|stimulation of synaptic metaplasticity http://purl.obolibrary.org/obo/GO_0031918 CHEBI:65220 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65220 chebi_ph7_3 CHEBI:41275 biolink:ChemicalSubstance 1H-benzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_41275 chebi_ph7_3 GO:0031915 biolink:BiologicalProcess positive regulation of synaptic plasticity A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. go-plus.json stimulation of synaptic plasticity|up-regulation of synaptic plasticity|upregulation of synaptic plasticity|up regulation of synaptic plasticity|activation of synaptic plasticity http://purl.obolibrary.org/obo/GO_0031915 CHEBI:65221 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65221 chebi_ph7_3 GO:0031916 biolink:BiologicalProcess regulation of synaptic metaplasticity A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require. go-plus.json http://purl.obolibrary.org/obo/GO_0031916 CHEBI:65228 biolink:ChemicalSubstance 3-hydroxyphenyl propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_65228 chebi_ph7_3 GO:1905010 biolink:BiologicalProcess positive regulation of L-lysine import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-lysine import into cell. go-plus.json activation of L-lysine import into cell|up-regulation of L-lysine import into cell|positive regulation of L-lysine import into cell|upregulation of L-lysine import into cell|up regulation of L-lysine import into cell http://purl.obolibrary.org/obo/GO_1905010 GO:1905011 biolink:BiologicalProcess transmembrane phosphate ion transport from cytosol to vacuole The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen. go-plus.json vacuolar phosphate transport http://purl.obolibrary.org/obo/GO_1905011 GO:1905012 biolink:BiologicalProcess regulation of 'de novo' NAD biosynthetic process from tryptophan Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan. go-plus.json regulation of de novo NAD biosynthetic process from tryptophan http://purl.obolibrary.org/obo/GO_1905012 GO:1905013 biolink:BiologicalProcess negative regulation of 'de novo' NAD biosynthetic process from tryptophan Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan. go-plus.json inhibition of de novo NAD biosynthetic process from tryptophan|down-regulation of 'de novo' NAD biosynthetic process from tryptophan|downregulation of 'de novo' NAD biosynthetic process from tryptophan|down-regulation of de novo NAD biosynthetic process from tryptophan|negative regulation of de novo NAD biosynthetic process from tryptophan|down regulation of 'de novo' NAD biosynthetic process from tryptophan|inhibition of 'de novo' NAD biosynthetic process from tryptophan|downregulation of de novo NAD biosynthetic process from tryptophan|down regulation of de novo NAD biosynthetic process from tryptophan http://purl.obolibrary.org/obo/GO_1905013 GO:1905014 biolink:BiologicalProcess positive regulation of 'de novo' NAD biosynthetic process from tryptophan Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan. go-plus.json activation of 'de novo' NAD biosynthetic process from tryptophan|up-regulation of de novo NAD biosynthetic process from tryptophan|up regulation of 'de novo' NAD biosynthetic process from tryptophan|activation of de novo NAD biosynthetic process from tryptophan|positive regulation of de novo NAD biosynthetic process from tryptophan|up regulation of de novo NAD biosynthetic process from tryptophan|upregulation of 'de novo' NAD biosynthetic process from tryptophan|upregulation of de novo NAD biosynthetic process from tryptophan|up-regulation of 'de novo' NAD biosynthetic process from tryptophan http://purl.obolibrary.org/obo/GO_1905014 GO:0090448 biolink:MolecularActivity glucosinolate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in). go-plus.json glucosinolate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0090448 GO:1905004 biolink:BiologicalProcess picolinic acid biosynthetic process The chemical reactions and pathways resulting in the formation of picolinic acid. go-plus.json picolinic acid biosynthesis|picolinate biosynthetic process|picolinate biosynthesis|picolinic acid anabolism|picolinic acid synthesis|picolinic acid formation http://purl.obolibrary.org/obo/GO_1905004 GO:0090449 biolink:BiologicalProcess phloem glucosinolate loading The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink. go-plus.json http://purl.obolibrary.org/obo/GO_0090449 GO:1905005 biolink:BiologicalProcess regulation of epithelial to mesenchymal transition involved in endocardial cushion formation Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. go-plus.json http://purl.obolibrary.org/obo/GO_1905005 GO:0090446 biolink:BiologicalProcess negative regulation of nematode larval development, heterochronic Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached. go-plus.json http://purl.obolibrary.org/obo/GO_0090446 GO:1905006 biolink:BiologicalProcess negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. go-plus.json downregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|down regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|inhibition of epithelial to mesenchymal transition involved in endocardial cushion formation|down-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation http://purl.obolibrary.org/obo/GO_1905006 GO:0090447 biolink:MolecularActivity glycerol-3-phosphate 2-O-acyltransferase activity Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0090447 GO:1905007 biolink:BiologicalProcess positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. go-plus.json up regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|upregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|activation of epithelial to mesenchymal transition involved in endocardial cushion formation|up-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation http://purl.obolibrary.org/obo/GO_1905007 GO:1905008 biolink:BiologicalProcess regulation of L-lysine import across plasma membrane Any process that modulates the frequency, rate or extent of L-lysine import into cell. go-plus.json regulation of L-lysine import into cell|regulation of lysine import|regulation of lysine uptake http://purl.obolibrary.org/obo/GO_1905008 GO:1905009 biolink:BiologicalProcess negative regulation of L-lysine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell. go-plus.json inhibition of L-lysine import into cell|negative regulation of lysine uptake|negative regulation of L-lysine import into cell|down regulation of L-lysine import into cell|downregulation of L-lysine import into cell|negative regulation of lysine import|down-regulation of L-lysine import into cell http://purl.obolibrary.org/obo/GO_1905009 GO:0090440 biolink:MolecularActivity abscisic acid transmembrane transporter activity Enables the transfer of abscisic acid from one side of a membrane to the other. go-plus.json abscisic acid transporter activity http://purl.obolibrary.org/obo/GO_0090440 GO:0090441 biolink:BiologicalProcess trehalose biosynthesis in response to heat stress The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. go-plus.json trehalose biosynthetic process in response to heat stress http://purl.obolibrary.org/obo/GO_0090441 GO:0090444 biolink:BiologicalProcess regulation of nematode larval development, heterochronic Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached. go-plus.json http://purl.obolibrary.org/obo/GO_0090444 GO:0090445 biolink:BiologicalProcess positive regulation of nematode larval development, heterochronic Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached. go-plus.json http://purl.obolibrary.org/obo/GO_0090445 GO:0090442 biolink:BiologicalProcess trehalose catabolism in response to heat stress The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. go-plus.json trehalose catabolic process in response to heat stress http://purl.obolibrary.org/obo/GO_0090442 GO:0090443 biolink:CellularComponent FAR/SIN/STRIPAK complex A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body. go-plus.json SIP complex|STRIPAK signalling complex|FAR complex|striatin interacting phosphatase and kinase complex http://purl.obolibrary.org/obo/GO_0090443 GO:1905020 biolink:BiologicalProcess positive regulation of methionine-tRNA ligase activity Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity. go-plus.json positive regulation of methionine translase activity|upregulation of methionyl-transfer ribonucleic acid synthetase activity|upregulation of L-methionine:tRNAMet ligase (AMP-forming)|upregulation of MetRS activity|up-regulation of methionine-tRNA ligase activity|activation of methionyl-tRNA synthetase activity|up-regulation of methionyl-tRNA synthetase activity|up-regulation of methionyl-transfer ribonucleate synthetase activity|up-regulation of methionyl-transfer RNA synthetase activity|activation of methionyl-transfer RNA synthetase activity|up regulation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of methionine translase activity|up regulation of L-methionine:tRNAMet ligase (AMP-forming)|activation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of MetRS activity|activation of MetRS activity|positive regulation of methionyl-transfer ribonucleic acid synthetase activity|activation of L-methionine:tRNAMet ligase (AMP-forming)|positive regulation of L-methionine:tRNAMet ligase (AMP-forming)|upregulation of methionine-tRNA ligase activity|upregulation of methionyl-transfer ribonucleate synthetase activity|positive regulation of methionyl-tRNA synthetase activity|positive regulation of methionyl-transfer RNA synthetase activity|upregulation of methionine translase activity|up regulation of methionyl-tRNA synthetase activity|up regulation of methionyl-transfer RNA synthetase activity|positive regulation of MetRS activity|up-regulation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of L-methionine:tRNAMet ligase (AMP-forming)|up regulation of MetRS activity|up regulation of methionine-tRNA ligase activity|up regulation of methionyl-transfer ribonucleate synthetase activity|activation of methionine-tRNA ligase activity|activation of methionyl-transfer ribonucleate synthetase activity|positive regulation of methionyl-transfer ribonucleate synthetase activity|up regulation of methionine translase activity|upregulation of methionyl-tRNA synthetase activity|activation of methionine translase activity|upregulation of methionyl-transfer RNA synthetase activity http://purl.obolibrary.org/obo/GO_1905020 GO:1905021 biolink:BiologicalProcess regulation of threonine-tRNA ligase activity Any process that modulates the frequency, rate or extent of threonine-tRNA ligase activity. go-plus.json regulation of threonyl ribonucleic synthetase activity|regulation of TRS|regulation of threonyl-transfer ribonucleate synthetase activity|regulation of threonine translase activity|regulation of threonyl-tRNA synthetase activity|regulation of threonyl-transfer RNA synthetase activity|regulation of threonine-transfer ribonucleate synthetase activity|regulation of threonyl-transfer ribonucleic acid synthetase activity|regulation of L-threonine:tRNAThr ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_1905021 GO:1905022 biolink:BiologicalProcess negative regulation of threonine-tRNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of threonine-tRNA ligase activity. go-plus.json downregulation of threonyl ribonucleic synthetase activity|downregulation of threonine-tRNA ligase activity|down regulation of TRS|downregulation of threonyl-transfer ribonucleate synthetase activity|down regulation of threonyl ribonucleic synthetase activity|downregulation of TRS|downregulation of threonine translase activity|down regulation of threonine-tRNA ligase activity|down regulation of threonyl-tRNA synthetase activity|inhibition of threonyl ribonucleic synthetase activity|down regulation of threonyl-transfer RNA synthetase activity|down regulation of threonyl-transfer ribonucleate synthetase activity|inhibition of threonine-tRNA ligase activity|down regulation of threonine-transfer ribonucleate synthetase activity|down-regulation of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonyl-transfer ribonucleic acid synthetase activity|inhibition of threonyl-transfer ribonucleate synthetase activity|downregulation of threonyl-tRNA synthetase activity|down-regulation of L-threonine:tRNAThr ligase (AMP-forming)|negative regulation of L-threonine:tRNAThr ligase (AMP-forming)|down regulation of threonine translase activity|downregulation of threonyl-transfer RNA synthetase activity|inhibition of threonine translase activity|downregulation of threonine-transfer ribonucleate synthetase activity|negative regulation of TRS|down-regulation of TRS|downregulation of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl-tRNA synthetase activity|negative regulation of threonyl-tRNA synthetase activity|downregulation of L-threonine:tRNAThr ligase (AMP-forming)|down-regulation of threonyl-transfer RNA synthetase activity|negative regulation of threonyl-transfer RNA synthetase activity|negative regulation of threonine-transfer ribonucleate synthetase activity|down-regulation of threonine-transfer ribonucleate synthetase activity|down regulation of threonyl-transfer ribonucleic acid synthetase activity|down regulation of L-threonine:tRNAThr ligase (AMP-forming)|negative regulation of threonyl ribonucleic synthetase activity|inhibition of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl ribonucleic synthetase activity|down-regulation of threonine-tRNA ligase activity|inhibition of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of threonyl-tRNA synthetase activity|negative regulation of threonyl-transfer ribonucleate synthetase activity|down-regulation of threonyl-transfer ribonucleate synthetase activity|inhibition of TRS|inhibition of threonyl-transfer RNA synthetase activity|inhibition of threonine-transfer ribonucleate synthetase activity|down-regulation of threonine translase activity|negative regulation of threonine translase activity http://purl.obolibrary.org/obo/GO_1905022 GO:1905023 biolink:BiologicalProcess positive regulation of threonine-tRNA ligase activity Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity. go-plus.json up regulation of threonyl ribonucleic synthetase activity|positive regulation of threonyl-transfer ribonucleate synthetase activity|up regulation of threonine-tRNA ligase activity|upregulation of TRS|up regulation of threonyl-transfer ribonucleate synthetase activity|positive regulation of threonine translase activity|up-regulation of threonyl-transfer ribonucleic acid synthetase activity|up-regulation of L-threonine:tRNAThr ligase (AMP-forming)|activation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of threonine translase activity|upregulation of threonyl-tRNA synthetase activity|upregulation of threonyl-transfer RNA synthetase activity|activation of L-threonine:tRNAThr ligase (AMP-forming)|upregulation of threonine-transfer ribonucleate synthetase activity|upregulation of threonyl ribonucleic synthetase activity|up regulation of TRS|upregulation of threonine-tRNA ligase activity|upregulation of threonyl-transfer ribonucleate synthetase activity|positive regulation of TRS|up regulation of threonyl-tRNA synthetase activity|upregulation of threonine translase activity|positive regulation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of threonyl-transfer RNA synthetase activity|positive regulation of L-threonine:tRNAThr ligase (AMP-forming)|up regulation of threonine-transfer ribonucleate synthetase activity|activation of threonyl-tRNA synthetase activity|positive regulation of threonyl-tRNA synthetase activity|up regulation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of L-threonine:tRNAThr ligase (AMP-forming)|activation of TRS|activation of threonyl-transfer RNA synthetase activity|positive regulation of threonyl-transfer RNA synthetase activity|positive regulation of threonine-transfer ribonucleate synthetase activity|activation of threonine-transfer ribonucleate synthetase activity|up-regulation of threonyl ribonucleic synthetase activity|up-regulation of threonine-tRNA ligase activity|activation of threonyl ribonucleic synthetase activity|up-regulation of threonyl-transfer ribonucleate synthetase activity|activation of threonine-tRNA ligase activity|activation of threonyl-transfer ribonucleate synthetase activity|up-regulation of TRS|up-regulation of threonine translase activity|activation of threonine translase activity|upregulation of threonyl-transfer ribonucleic acid synthetase activity|upregulation of L-threonine:tRNAThr ligase (AMP-forming)|up-regulation of threonyl-tRNA synthetase activity|up-regulation of threonyl-transfer RNA synthetase activity|positive regulation of threonyl ribonucleic synthetase activity|up-regulation of threonine-transfer ribonucleate synthetase activity http://purl.obolibrary.org/obo/GO_1905023 GO:1905024 biolink:BiologicalProcess regulation of membrane repolarization during ventricular cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. go-plus.json regulation of electrocardiogram T wave|regulation of regulation of ventricular cardiac muscle repolarization|regulation of ventricular repolarization http://purl.obolibrary.org/obo/GO_1905024 GO:1905025 biolink:BiologicalProcess negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. go-plus.json inhibition of regulation of ventricular cardiac muscle repolarization|inhibition of ventricular repolarization|down regulation of membrane repolarization during ventricular cardiac muscle cell action potential|downregulation of electrocardiogram T wave|down regulation of regulation of ventricular cardiac muscle repolarization|downregulation of membrane repolarization during ventricular cardiac muscle cell action potential|down regulation of electrocardiogram T wave|downregulation of regulation of ventricular cardiac muscle repolarization|down-regulation of ventricular repolarization|negative regulation of ventricular repolarization|inhibition of electrocardiogram T wave|down-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|down-regulation of regulation of ventricular cardiac muscle repolarization|negative regulation of regulation of ventricular cardiac muscle repolarization|downregulation of ventricular repolarization|inhibition of membrane repolarization during ventricular cardiac muscle cell action potential|down regulation of ventricular repolarization|down-regulation of electrocardiogram T wave|negative regulation of electrocardiogram T wave http://purl.obolibrary.org/obo/GO_1905025 GO:1905015 biolink:BiologicalProcess regulation of isoleucine-tRNA ligase activity Any process that modulates the frequency, rate or extent of isoleucine-tRNA ligase activity. go-plus.json regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|regulation of isoleucine-tRNA synthetase activity|regulation of isoleucyl-transfer ribonucleate synthetase activity|regulation of isoleucine-transfer RNA ligase activity|regulation of isoleucyl-tRNA synthetase activity|regulation of isoleucine translase activity|regulation of isoleucyl-transfer RNA synthetase activity http://purl.obolibrary.org/obo/GO_1905015 GO:0090459 biolink:BiologicalProcess aspartate homeostasis Any process involved in the maintenance of an internal steady state of aspartate within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090459 GO:1905016 biolink:BiologicalProcess negative regulation of isoleucine-tRNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity. go-plus.json down regulation of isoleucyl-transfer RNA synthetase activity|inhibition of isoleucyl-tRNA synthetase activity|inhibition of L-isoleucine:tRNAIle ligase (AMP-forming)|inhibition of isoleucyl-transfer RNA synthetase activity|negative regulation of isoleucine-tRNA synthetase activity|down-regulation of isoleucine-tRNA synthetase activity|down-regulation of isoleucine-tRNA ligase activity|negative regulation of isoleucine-transfer RNA ligase activity|down-regulation of isoleucyl-transfer ribonucleate synthetase activity|negative regulation of isoleucyl-transfer ribonucleate synthetase activity|down-regulation of isoleucine-transfer RNA ligase activity|down-regulation of isoleucine translase activity|negative regulation of isoleucine translase activity|inhibition of isoleucine-tRNA synthetase activity|inhibition of isoleucine-tRNA ligase activity|inhibition of isoleucyl-transfer ribonucleate synthetase activity|inhibition of isoleucine-transfer RNA ligase activity|down regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|inhibition of isoleucine translase activity|down-regulation of isoleucyl-tRNA synthetase activity|downregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of isoleucyl-tRNA synthetase activity|down-regulation of isoleucyl-transfer RNA synthetase activity|negative regulation of isoleucyl-transfer RNA synthetase activity|down regulation of isoleucine-tRNA synthetase activity|down regulation of isoleucine-tRNA ligase activity|down regulation of isoleucyl-transfer ribonucleate synthetase activity|down regulation of isoleucine-transfer RNA ligase activity|downregulation of isoleucine-tRNA synthetase activity|down-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|downregulation of isoleucyl-tRNA synthetase activity|down regulation of isoleucine translase activity|downregulation of isoleucine-tRNA ligase activity|downregulation of isoleucine-transfer RNA ligase activity|downregulation of isoleucyl-transfer ribonucleate synthetase activity|downregulation of isoleucyl-transfer RNA synthetase activity|downregulation of isoleucine translase activity|down regulation of isoleucyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_1905016 GO:1905017 biolink:BiologicalProcess positive regulation of isoleucine-tRNA ligase activity Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity. go-plus.json positive regulation of isoleucine-tRNA synthetase activity|up regulation of isoleucine-transfer RNA ligase activity|activation of isoleucine-tRNA ligase activity|up regulation of isoleucyl-transfer ribonucleate synthetase activity|activation of isoleucyl-transfer ribonucleate synthetase activity|activation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucine translase activity|upregulation of isoleucyl-tRNA synthetase activity|activation of isoleucine translase activity|upregulation of isoleucyl-transfer RNA synthetase activity|positive regulation of isoleucine translase activity|up-regulation of isoleucine-tRNA synthetase activity|up-regulation of isoleucyl-tRNA synthetase activity|activation of isoleucyl-tRNA synthetase activity|upregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up-regulation of isoleucine-tRNA ligase activity|up-regulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucine-transfer RNA ligase activity|activation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucine translase activity|upregulation of isoleucine-tRNA synthetase activity|upregulation of isoleucine-tRNA ligase activity|up regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|upregulation of isoleucine-transfer RNA ligase activity|upregulation of isoleucyl-transfer ribonucleate synthetase activity|positive regulation of isoleucyl-tRNA synthetase activity|activation of L-isoleucine:tRNAIle ligase (AMP-forming)|positive regulation of isoleucyl-transfer RNA synthetase activity|positive regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucyl-tRNA synthetase activity|upregulation of isoleucine translase activity|up regulation of isoleucyl-transfer RNA synthetase activity|up regulation of isoleucine-tRNA synthetase activity|up regulation of isoleucine-tRNA ligase activity|activation of isoleucine-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_1905017 GO:0090457 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090457 GO:0090458 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090458 GO:1905018 biolink:BiologicalProcess regulation of methionine-tRNA ligase activity Any process that modulates the frequency, rate or extent of methionine-tRNA ligase activity. go-plus.json regulation of methionyl-transfer ribonucleate synthetase activity|regulation of methionyl-tRNA synthetase activity|regulation of methionine translase activity|regulation of methionyl-transfer RNA synthetase activity|regulation of MetRS activity|regulation of methionyl-transfer ribonucleic acid synthetase activity|regulation of L-methionine:tRNAMet ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_1905018 GO:1905019 biolink:BiologicalProcess negative regulation of methionine-tRNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of methionine-tRNA ligase activity. go-plus.json inhibition of methionine translase activity|negative regulation of methionyl-tRNA synthetase activity|down-regulation of methionyl-tRNA synthetase activity|down-regulation of methionyl-transfer RNA synthetase activity|negative regulation of methionyl-transfer RNA synthetase activity|negative regulation of methionyl-transfer ribonucleic acid synthetase activity|down-regulation of methionyl-transfer ribonucleic acid synthetase activity|negative regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of L-methionine:tRNAMet ligase (AMP-forming)|negative regulation of MetRS activity|down-regulation of MetRS activity|down regulation of methionine-tRNA ligase activity|down regulation of methionyl-transfer ribonucleate synthetase activity|inhibition of methionyl-transfer ribonucleic acid synthetase activity|downregulation of methionine-tRNA ligase activity|down regulation of methionine translase activity|downregulation of methionyl-tRNA synthetase activity|inhibition of L-methionine:tRNAMet ligase (AMP-forming)|downregulation of methionyl-transfer ribonucleate synthetase activity|downregulation of methionyl-transfer RNA synthetase activity|downregulation of MetRS activity|downregulation of methionine translase activity|down regulation of methionyl-tRNA synthetase activity|inhibition of methionyl-tRNA synthetase activity|down regulation of methionyl-transfer RNA synthetase activity|inhibition of methionyl-transfer RNA synthetase activity|down regulation of MetRS activity|inhibition of MetRS activity|down-regulation of methionine-tRNA ligase activity|down-regulation of methionyl-transfer ribonucleate synthetase activity|negative regulation of methionyl-transfer ribonucleate synthetase activity|down regulation of methionyl-transfer ribonucleic acid synthetase activity|down regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of methionine translase activity|negative regulation of methionine translase activity|inhibition of methionine-tRNA ligase activity|inhibition of methionyl-transfer ribonucleate synthetase activity|downregulation of methionyl-transfer ribonucleic acid synthetase activity|downregulation of L-methionine:tRNAMet ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_1905019 GO:0090451 biolink:BiologicalProcess cotyledon boundary formation The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0090451 GO:0090452 biolink:BiologicalProcess lithium ion transmembrane transport The directed movement of lithium ions across a membrane. go-plus.json lithium ion import|lithium ion uptake http://purl.obolibrary.org/obo/GO_0090452 GO:0090450 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090450 GO:0090455 biolink:BiologicalProcess ornithine transmembrane import into vacuole The directed movement of ornithine into the vacuole across the vacuolar membrane. go-plus.json vacuolar ornithine import http://purl.obolibrary.org/obo/GO_0090455 GO:0090456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090456 GO:0090453 biolink:BiologicalProcess aspartate transmembrane import into vacuole The directed movement of aspartate into the vacuole across the vacuolar membrane. go-plus.json vacuolar aspartate import http://purl.obolibrary.org/obo/GO_0090453 GO:0090454 biolink:BiologicalProcess glutamate transmembrane import into vacuole The directed movement of glutamate into the vacuole across the vacuolar membrane. go-plus.json vacuolar glutamate import http://purl.obolibrary.org/obo/GO_0090454 IAO:0000409 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/IAO_0000409 NCBITaxon:314145 biolink:OrganismalEntity Laurasiatheria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_314145 NCBITaxon:314146 biolink:OrganismalEntity Euarchontoglires go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_314146 NCBITaxon:314147 biolink:OrganismalEntity Glires go-plus.json Rodents and rabbits http://purl.obolibrary.org/obo/NCBITaxon_314147 GO:1905030 biolink:MolecularActivity voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. go-plus.json voltage-dependent ion channel activity involved in regulation of post-synaptic membrane potential|voltage-gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of postsynaptic membrane potential|voltage gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage gated ion channel activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_1905030 goslim_synapse GO:1905031 biolink:BiologicalProcess regulation of membrane repolarization during cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. go-plus.json http://purl.obolibrary.org/obo/GO_1905031 GO:1905032 biolink:BiologicalProcess negative regulation of membrane repolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. go-plus.json down-regulation of membrane repolarization during cardiac muscle cell action potential|inhibition of membrane repolarization during cardiac muscle cell action potential|down regulation of membrane repolarization during cardiac muscle cell action potential|downregulation of membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905032 GO:1905033 biolink:BiologicalProcess positive regulation of membrane repolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. go-plus.json up-regulation of membrane repolarization during cardiac muscle cell action potential|upregulation of membrane repolarization during cardiac muscle cell action potential|up regulation of membrane repolarization during cardiac muscle cell action potential|activation of membrane repolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905033 GO:1905034 biolink:BiologicalProcess regulation of antifungal innate immune response Any process that modulates the frequency, rate or extent of an antifungal innate immune response. go-plus.json http://purl.obolibrary.org/obo/GO_1905034 GO:1905035 biolink:BiologicalProcess negative regulation of antifungal innate immune response Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response. go-plus.json inhibition of antifungal innate immune response|down regulation of antifungal innate immune response|downregulation of antifungal innate immune response|down-regulation of antifungal innate immune response http://purl.obolibrary.org/obo/GO_1905035 GO:1905036 biolink:BiologicalProcess positive regulation of antifungal innate immune response Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response. go-plus.json up-regulation of antifungal innate immune response|upregulation of antifungal innate immune response|up regulation of antifungal innate immune response|activation of antifungal innate immune response http://purl.obolibrary.org/obo/GO_1905036 GO:1905026 biolink:BiologicalProcess positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. go-plus.json upregulation of ventricular repolarization|positive regulation of electrocardiogram T wave|upregulation of membrane repolarization during ventricular cardiac muscle cell action potential|up regulation of electrocardiogram T wave|upregulation of regulation of ventricular cardiac muscle repolarization|up-regulation of ventricular repolarization|up regulation of membrane repolarization during ventricular cardiac muscle cell action potential|upregulation of electrocardiogram T wave|activation of membrane repolarization during ventricular cardiac muscle cell action potential|activation of ventricular repolarization|up regulation of regulation of ventricular cardiac muscle repolarization|positive regulation of regulation of ventricular cardiac muscle repolarization|positive regulation of ventricular repolarization|up regulation of ventricular repolarization|up-regulation of electrocardiogram T wave|activation of regulation of ventricular cardiac muscle repolarization|up-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|activation of electrocardiogram T wave|up-regulation of regulation of ventricular cardiac muscle repolarization http://purl.obolibrary.org/obo/GO_1905026 GO:0090426 biolink:BiologicalProcess actin filament bundle convergence A process of actin filament bundle distribution that results in the compaction of actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0090426 GO:0090427 biolink:BiologicalProcess activation of meiosis Any process that starts the inactive process of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0090427 GO:1905027 biolink:BiologicalProcess regulation of membrane depolarization during AV node cell action potential Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential. go-plus.json regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|regulation of membrane depolarization during AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905027 GO:0090424 biolink:BiologicalProcess phytochelatin-metal-sulfur complex formation A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex. go-plus.json high molecular weight phytochelatin complex formation|HWM phytochelatin complex formation http://purl.obolibrary.org/obo/GO_0090424 GO:1905028 biolink:BiologicalProcess negative regulation of membrane depolarization during AV node cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential. go-plus.json down regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|downregulation of membrane depolarization during AV node cell action potential|downregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down regulation of membrane depolarization during AV node cardiac muscle cell action potential|down regulation of membrane depolarization during AV node cell action potential|inhibition of membrane depolarization during AV node cell action potential|downregulation of membrane depolarization during AV node cardiac muscle cell action potential|negative regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cardiac muscle cell action potential|negative regulation of membrane depolarization during AV node cardiac muscle cell action potential|inhibition of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cell action potential|inhibition of membrane depolarization during AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905028 GO:1905029 biolink:BiologicalProcess positive regulation of membrane depolarization during AV node cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential. go-plus.json upregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cell action potential|upregulation of membrane depolarization during AV node cardiac muscle cell action potential|up regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|upregulation of membrane depolarization during AV node cell action potential|activation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|positive regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cardiac muscle cell action potential|activation of membrane depolarization during AV node cardiac muscle cell action potential|positive regulation of membrane depolarization during AV node cardiac muscle cell action potential|up-regulation of membrane depolarization during AV node cell action potential|activation of membrane depolarization during AV node cell action potential|up-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up-regulation of membrane depolarization during AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1905029 GO:0090425 biolink:BiologicalProcess acinar cell differentiation The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. go-plus.json http://purl.obolibrary.org/obo/GO_0090425 GO:0090428 biolink:BiologicalProcess perianth development The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals. go-plus.json http://purl.obolibrary.org/obo/GO_0090428 GO:0090429 biolink:BiologicalProcess detection of endogenous biotic stimulus The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0090429 GO:0090422 biolink:MolecularActivity thiamine pyrophosphate transmembrane transporter activity Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other. Reactome:R-HSA-8875838 go-plus.json thiamine pyrophosphate transporter activity|thiamine diphosphate transporter activity http://purl.obolibrary.org/obo/GO_0090422 GO:0090423 biolink:BiologicalProcess phytochelatin-metal complex formation A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex. go-plus.json LWM phytochelatin complex formation|low molecular weight phytochelatin complex formation http://purl.obolibrary.org/obo/GO_0090423 IAO:0000410 biolink:OntologyClass universal go-plus.json http://purl.obolibrary.org/obo/IAO_0000410 GO:0090420 biolink:BiologicalProcess obsolete naphthalene-containing compound metabolic process OBSOLETE. The chemical reactions and pathways involving naphthalene-containing compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0090420 GO:0090421 biolink:BiologicalProcess embryonic meristem initiation Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0090421 GO:1905040 biolink:BiologicalProcess otic placode development The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure. go-plus.json ear placode development|octaval VIII placode development|placoda otica development|octaval placode development|auditory placode development|ear/otic placode development http://purl.obolibrary.org/obo/GO_1905040 GO:1905041 biolink:BiologicalProcess regulation of epithelium regeneration Any process that modulates the frequency, rate or extent of epithelium regeneration. go-plus.json regulation of regeneration of epithelium http://purl.obolibrary.org/obo/GO_1905041 GO:1905042 biolink:BiologicalProcess negative regulation of epithelium regeneration Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration. go-plus.json inhibition of epithelium regeneration|down-regulation of regeneration of epithelium|negative regulation of regeneration of epithelium|down regulation of epithelium regeneration|downregulation of regeneration of epithelium|downregulation of epithelium regeneration|down regulation of regeneration of epithelium|inhibition of regeneration of epithelium|down-regulation of epithelium regeneration http://purl.obolibrary.org/obo/GO_1905042 GO:1905043 biolink:BiologicalProcess positive regulation of epithelium regeneration Any process that activates or increases the frequency, rate or extent of epithelium regeneration. go-plus.json up-regulation of epithelium regeneration|positive regulation of regeneration of epithelium|upregulation of epithelium regeneration|up regulation of regeneration of epithelium|up regulation of epithelium regeneration|upregulation of regeneration of epithelium|activation of epithelium regeneration|up-regulation of regeneration of epithelium|activation of regeneration of epithelium http://purl.obolibrary.org/obo/GO_1905043 GO:1905044 biolink:BiologicalProcess regulation of Schwann cell proliferation involved in axon regeneration Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration. go-plus.json http://purl.obolibrary.org/obo/GO_1905044 GO:1905045 biolink:BiologicalProcess negative regulation of Schwann cell proliferation involved in axon regeneration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration. go-plus.json down-regulation of Schwann cell proliferation involved in axon regeneration|downregulation of Schwann cell proliferation involved in axon regeneration|down regulation of Schwann cell proliferation involved in axon regeneration|inhibition of Schwann cell proliferation involved in axon regeneration http://purl.obolibrary.org/obo/GO_1905045 GO:1905046 biolink:BiologicalProcess positive regulation of Schwann cell proliferation involved in axon regeneration Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration. go-plus.json up regulation of Schwann cell proliferation involved in axon regeneration|upregulation of Schwann cell proliferation involved in axon regeneration|up-regulation of Schwann cell proliferation involved in axon regeneration|activation of Schwann cell proliferation involved in axon regeneration http://purl.obolibrary.org/obo/GO_1905046 GO:1905047 biolink:BiologicalProcess mitotic spindle pole body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_1905047 GO:0090437 biolink:BiologicalProcess socket cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support. go-plus.json http://purl.obolibrary.org/obo/GO_0090437 GO:1905037 biolink:BiologicalProcess autophagosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. go-plus.json autophagic vacuole organization|initial autophagic vacuole organization http://purl.obolibrary.org/obo/GO_1905037 GO:0090438 biolink:MolecularActivity camelliol C synthase activity Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C. go-plus.json (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming) http://purl.obolibrary.org/obo/GO_0090438 GO:1905038 biolink:BiologicalProcess regulation of membrane lipid metabolic process Any process that modulates the frequency, rate or extent of membrane lipid metabolic process. go-plus.json regulation of membrane lipid metabolism http://purl.obolibrary.org/obo/GO_1905038 GO:0090435 biolink:BiologicalProcess protein localization to nuclear envelope A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. go-plus.json protein localization in nuclear envelope http://purl.obolibrary.org/obo/GO_0090435 GO:1905039 biolink:BiologicalProcess carboxylic acid transmembrane transport The process in which carboxylic acid is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905039 GO:0090436 biolink:BiologicalProcess leaf pavement cell development The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0090436 GO:0090439 biolink:MolecularActivity tetraketide alpha-pyrone synthase activity Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A . go-plus.json http://purl.obolibrary.org/obo/GO_0090439 GO:0090430 biolink:MolecularActivity caffeoyl-CoA: alcohol caffeoyl transferase activity Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA. go-plus.json http://purl.obolibrary.org/obo/GO_0090430 IAO:0000423 biolink:OntologyClass to be replaced with external ontology term Terms with this status should eventually replaced with a term from another ontology. go-plus.json http://purl.obolibrary.org/obo/IAO_0000423 IAO:0000420 biolink:OntologyClass defined class A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal go-plus.json http://purl.obolibrary.org/obo/IAO_0000420 GO:0090433 biolink:MolecularActivity palmitoyl-CoA ligase activity Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA. Reactome:R-HSA-434382 go-plus.json palmitoyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0090433 IAO:0000421 biolink:OntologyClass named class expression A named class expression is a logical expression that is given a name. The name can be used in place of the expression. go-plus.json http://purl.obolibrary.org/obo/IAO_0000421 GO:0090434 biolink:MolecularActivity oleoyl-CoA ligase activity Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA. go-plus.json oleoyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0090434 GO:0090431 biolink:BiologicalProcess alkyl caffeate ester biosynthetic process The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate. go-plus.json alkyl caffeate ester anabolism|alkyl caffeate ester biosynthesis|alkyl caffeate ester synthesis|alkyl caffeate ester formation http://purl.obolibrary.org/obo/GO_0090431 GO:0090432 biolink:MolecularActivity myristoyl-CoA ligase activity Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA. go-plus.json myristoyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0090432 GO:0090480 biolink:BiologicalProcess purine nucleotide-sugar transmembrane transport The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json purine nucleotide-sugar transport|purine nucleotide-sugar membrane transport http://purl.obolibrary.org/obo/GO_0090480 GO:0090481 biolink:BiologicalProcess pyrimidine nucleotide-sugar transmembrane transport The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json pyrimidine nucleotide-sugar transport|pyrimidine nucleotide-sugar membrane transport http://purl.obolibrary.org/obo/GO_0090481 GO:1905050 biolink:BiologicalProcess positive regulation of metallopeptidase activity Any process that activates or increases the frequency, rate or extent of metallopeptidase activity. go-plus.json upregulation of metallopeptidase activity|upregulation of metalloproteinase activity|upregulation of metalloprotease activity|up regulation of metallopeptidase activity|activation of metallopeptidase activity|up-regulation of metalloproteinase activity|up-regulation of metalloprotease activity|activation of metalloproteinase activity|positive regulation of metalloproteinase activity|activation of metalloprotease activity|up-regulation of metallopeptidase activity|up regulation of metalloproteinase activity|positive regulation of metalloprotease activity|up regulation of metalloprotease activity http://purl.obolibrary.org/obo/GO_1905050 GO:1905051 biolink:BiologicalProcess regulation of base-excision repair Any process that modulates the frequency, rate or extent of base-excision repair. go-plus.json regulation of BER http://purl.obolibrary.org/obo/GO_1905051 GO:1905052 biolink:BiologicalProcess negative regulation of base-excision repair Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair. go-plus.json inhibition of BER|down-regulation of base-excision repair|down regulation of BER|downregulation of BER|downregulation of base-excision repair|down regulation of base-excision repair|inhibition of base-excision repair|negative regulation of BER|down-regulation of BER http://purl.obolibrary.org/obo/GO_1905052 GO:1905053 biolink:BiologicalProcess positive regulation of base-excision repair Any process that activates or increases the frequency, rate or extent of base-excision repair. go-plus.json up-regulation of BER|up-regulation of base-excision repair|activation of base-excision repair|upregulation of BER|up regulation of base-excision repair|up regulation of BER|activation of BER|positive regulation of BER|upregulation of base-excision repair http://purl.obolibrary.org/obo/GO_1905053 GO:1905054 biolink:MolecularActivity calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration. go-plus.json calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_1905054 goslim_synapse GO:1905055 biolink:MolecularActivity calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration. go-plus.json calcium ion antiporter activity involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_1905055 goslim_synapse GO:1905056 biolink:MolecularActivity P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration A calcium-transporting P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration. go-plus.json ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of presynaptic cytosolic calcium levels|calcium ABC transporter involved in regulation of presynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of presynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium efflux ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|Ca2+-pumping ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|plasma membrane Ca-ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|Ca(2+)-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_1905056 goslim_synapse GO:1905057 biolink:MolecularActivity voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. go-plus.json depolarization-activated voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|dihydropyridine-sensitive calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-gated calcium ion channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels|voltage-dependent calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-sensitive calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_1905057 goslim_synapse GO:1905058 biolink:MolecularActivity calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. go-plus.json calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_1905058 goslim_synapse GO:1905048 biolink:BiologicalProcess regulation of metallopeptidase activity Any process that modulates the frequency, rate or extent of metallopeptidase activity. go-plus.json regulation of metalloproteinase activity|regulation of metalloprotease activity http://purl.obolibrary.org/obo/GO_1905048 GO:1905049 biolink:BiologicalProcess negative regulation of metallopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity. go-plus.json inhibition of metalloprotease activity|down-regulation of metallopeptidase activity|negative regulation of metalloproteinase activity|down-regulation of metalloproteinase activity|inhibition of metallopeptidase activity|negative regulation of metalloprotease activity|down-regulation of metalloprotease activity|downregulation of metalloproteinase activity|down regulation of metalloproteinase activity|downregulation of metalloprotease activity|down regulation of metallopeptidase activity|down regulation of metalloprotease activity|inhibition of metalloproteinase activity|downregulation of metallopeptidase activity http://purl.obolibrary.org/obo/GO_1905049 GO:0090484 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090484 GO:0090485 biolink:BiologicalProcess obsolete chromosome number maintenance OBSOLETE. The maintenance of the standard number of chromosomes in a cell. go-plus.json haploidization|diploidization http://purl.obolibrary.org/obo/GO_0090485 GO:0090482 biolink:MolecularActivity vitamin transmembrane transporter activity Enables the transfer of a vitamin from one side of a membrane to the other. go-plus.json vitamin or cofactor transporter activity|vitamin transporter activity http://purl.obolibrary.org/obo/GO_0090482 GO:0090483 biolink:MolecularActivity phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine. go-plus.json cardiolipin synthase http://purl.obolibrary.org/obo/GO_0090483 GO:0090488 biolink:MolecularActivity polo box domain specific binding Binding to a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases. go-plus.json http://purl.obolibrary.org/obo/GO_0090488 GO:0090489 biolink:MolecularActivity L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating) Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O. go-plus.json tryptophan N-monooxygenase activity http://purl.obolibrary.org/obo/GO_0090489 GO:0090486 biolink:MolecularActivity small RNA 2'-O-methyltransferase Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0090486 GO:0090487 biolink:BiologicalProcess secondary metabolite catabolic process The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. go-plus.json secondary metabolite degradation|secondary metabolite breakdown|secondary metabolite catabolism http://purl.obolibrary.org/obo/GO_0090487 GO:0090491 biolink:MolecularActivity N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0090491 GO:0090492 biolink:MolecularActivity N,N-Dihydroxy-L-tryptophan decarboxylase activity Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0090492 GO:1905060 biolink:MolecularActivity calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. go-plus.json calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion levels http://purl.obolibrary.org/obo/GO_1905060 goslim_synapse GO:1905061 biolink:BiologicalProcess negative regulation of cardioblast proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation. go-plus.json downregulation of cardioblast proliferation|down-regulation of cardioblast proliferation|inhibition of cardioblast proliferation|down regulation of cardioblast proliferation http://purl.obolibrary.org/obo/GO_1905061 GO:0090490 biolink:MolecularActivity L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0090490 GO:1905062 biolink:BiologicalProcess positive regulation of cardioblast proliferation Any process that activates or increases the frequency, rate or extent of cardioblast proliferation. go-plus.json up regulation of cardioblast proliferation|activation of cardioblast proliferation|up-regulation of cardioblast proliferation|upregulation of cardioblast proliferation http://purl.obolibrary.org/obo/GO_1905062 GO:1905063 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation. go-plus.json regulation of vascular smooth muscle cell differentiation|regulation of VSMC differentiation http://purl.obolibrary.org/obo/GO_1905063 GO:1905064 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation. go-plus.json down-regulation of VSMC differentiation|negative regulation of VSMC differentiation|downregulation of vascular associated smooth muscle cell differentiation|down regulation of vascular associated smooth muscle cell differentiation|inhibition of vascular associated smooth muscle cell differentiation|down regulation of vascular smooth muscle cell differentiation|downregulation of VSMC differentiation|downregulation of vascular smooth muscle cell differentiation|down regulation of VSMC differentiation|inhibition of VSMC differentiation|negative regulation of vascular smooth muscle cell differentiation|down-regulation of vascular smooth muscle cell differentiation|down-regulation of vascular associated smooth muscle cell differentiation|inhibition of vascular smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905064 GO:1905065 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation. go-plus.json activation of VSMC differentiation|up-regulation of vascular smooth muscle cell differentiation|up regulation of vascular associated smooth muscle cell differentiation|upregulation of vascular smooth muscle cell differentiation|positive regulation of VSMC differentiation|up regulation of VSMC differentiation|upregulation of vascular associated smooth muscle cell differentiation|up regulation of vascular smooth muscle cell differentiation|positive regulation of vascular smooth muscle cell differentiation|activation of vascular smooth muscle cell differentiation|upregulation of VSMC differentiation|up-regulation of vascular associated smooth muscle cell differentiation|activation of vascular associated smooth muscle cell differentiation|up-regulation of VSMC differentiation http://purl.obolibrary.org/obo/GO_1905065 GO:1905066 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway involved in heart development Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development. go-plus.json regulation of canonical Wnt receptor signalling pathway involved in heart development|regulation of canonical Wnt-activated signaling pathway involved in heart development|regulation of canonical Wnt receptor signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_1905066 GO:1905067 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway involved in heart development Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development. go-plus.json inhibition of canonical Wnt receptor signaling pathway involved in heart development|negative regulation of canonical Wnt-activated signaling pathway involved in heart development|down-regulation of canonical Wnt-activated signaling pathway involved in heart development|inhibition of canonical Wnt receptor signalling pathway involved in heart development|down-regulation of canonical Wnt signaling pathway involved in heart development|inhibition of canonical Wnt-activated signaling pathway involved in heart development|inhibition of canonical Wnt signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signaling pathway involved in heart development|negative regulation of canonical Wnt receptor signaling pathway involved in heart development|down regulation of canonical Wnt receptor signalling pathway involved in heart development|downregulation of canonical Wnt receptor signalling pathway involved in heart development|down regulation of canonical Wnt-activated signaling pathway involved in heart development|downregulation of canonical Wnt receptor signaling pathway involved in heart development|down regulation of canonical Wnt signaling pathway involved in heart development|downregulation of canonical Wnt-activated signaling pathway involved in heart development|down regulation of canonical Wnt receptor signaling pathway involved in heart development|downregulation of canonical Wnt signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signalling pathway involved in heart development|negative regulation of canonical Wnt receptor signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_1905067 GO:1905068 biolink:BiologicalProcess positive regulation of canonical Wnt signaling pathway involved in heart development Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development. go-plus.json positive regulation of canonical Wnt-activated signaling pathway involved in heart development|up regulation of canonical Wnt signaling pathway involved in heart development|upregulation of canonical Wnt receptor signaling pathway involved in heart development|activation of canonical Wnt signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt-activated signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt signaling pathway involved in heart development|upregulation of canonical Wnt receptor signalling pathway involved in heart development|upregulation of canonical Wnt-activated signaling pathway involved in heart development|positive regulation of canonical Wnt receptor signaling pathway involved in heart development|up regulation of canonical Wnt receptor signaling pathway involved in heart development|upregulation of canonical Wnt signaling pathway involved in heart development|up regulation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt receptor signalling pathway involved in heart development|positive regulation of canonical Wnt receptor signalling pathway involved in heart development|up regulation of canonical Wnt-activated signaling pathway involved in heart development|activation of canonical Wnt-activated signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_1905068 GO:1905069 biolink:BiologicalProcess allantois development The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure. go-plus.json allantoic bud development http://purl.obolibrary.org/obo/GO_1905069 GO:1905059 biolink:MolecularActivity P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration. go-plus.json Ca(2+)-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-pumping ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|sarcoplasmic reticulum ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium ABC transporter involved in regulation of postsynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of postsynaptic cytosolic calcium levels|sarco(endo)plasmic reticulum Ca2+-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|plasma membrane Ca-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium levels|calcium efflux ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_1905059 goslim_synapse GO:0090495 biolink:BiologicalProcess low-density lipoprotein particle disassembly The disaggregation of a low-density lipoprotein particle into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0090495 GO:0090496 biolink:BiologicalProcess mesenchyme migration involved in limb bud formation The migration of mesenchymal tissue that contributes to the formation of a limb bud. go-plus.json http://purl.obolibrary.org/obo/GO_0090496 GO:0090493 biolink:BiologicalProcess catecholamine uptake The directed movement of catecholamine into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090493 GO:0090494 biolink:BiologicalProcess dopamine uptake The directed movement of dopamine into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090494 GO:0090499 biolink:MolecularActivity pimelyl-[acyl-carrier protein] methyl ester esterase activity Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol. go-plus.json pimelyl-[acyl-carrier protein] methyl ester hydrolase activity http://purl.obolibrary.org/obo/GO_0090499 GO:0090497 biolink:BiologicalProcess mesenchymal cell migration The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0090497 CHEBI:5254 biolink:ChemicalSubstance galactolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_5254 GO:0090498 biolink:CellularComponent extrinsic component of Golgi membrane The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to Golgi membrane http://purl.obolibrary.org/obo/GO_0090498 GO:0016490 biolink:MolecularActivity structural constituent of peritrophic membrane The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster. go-plus.json structural constituent of peritrophic matrix http://purl.obolibrary.org/obo/GO_0016490 GO:1905070 biolink:BiologicalProcess anterior visceral endoderm cell migration The orderly movement of an anterior visceral endoderm cell from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_1905070 GO:1905071 biolink:BiologicalProcess tight junction disassembly The disaggregation of an tight junction into its constituent components. go-plus.json occluding junction disassembly|occluding cell junction disassembly http://purl.obolibrary.org/obo/GO_1905071 GO:1905072 biolink:BiologicalProcess cardiac jelly development The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. go-plus.json heart cardiac jelly development http://purl.obolibrary.org/obo/GO_1905072 GO:1905073 biolink:BiologicalProcess regulation of tight junction disassembly Any process that modulates the frequency, rate or extent of tight junction disassembly. go-plus.json regulation of occluding cell junction disassembly|regulation of occluding junction disassembly http://purl.obolibrary.org/obo/GO_1905073 GO:1905074 biolink:BiologicalProcess negative regulation of tight junction disassembly Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly. go-plus.json negative regulation of tight junction disassembly|down-regulation of tight junction disassembly|downregulation of occluding junction disassembly|downregulation of occluding cell junction disassembly|inhibition of occluding junction disassembly|downregulation of tight junction disassembly|down-regulation of occluding cell junction disassembly|negative regulation of occluding cell junction disassembly|down regulation of tight junction disassembly|inhibition of tight junction disassembly|inhibition of occluding cell junction disassembly|down regulation of occluding cell junction disassembly http://purl.obolibrary.org/obo/GO_1905074 GO:1905075 biolink:BiologicalProcess positive regulation of tight junction disassembly Any process that activates or increases the frequency, rate or extent of tight junction disassembly. go-plus.json up regulation of occluding cell junction disassembly|positive regulation of occluding cell junction disassembly|activation of occluding cell junction disassembly|up regulation of tight junction disassembly|upregulation of tight junction disassembly|up-regulation of occluding cell junction disassembly|activation of occluding junction disassembly|up-regulation of tight junction disassembly|upregulation of occluding cell junction disassembly|activation of tight junction disassembly|positive regulation of occluding junction disassembly http://purl.obolibrary.org/obo/GO_1905075 GO:1905076 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905076 GO:1905077 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905077 GO:1905078 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905078 GO:1905079 biolink:BiologicalProcess regulation of cerebellar neuron development Any process that modulates the frequency, rate or extent of cerebellar neuron development. go-plus.json http://purl.obolibrary.org/obo/GO_1905079 GO:0090468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090468 GO:0090469 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090469 GO:0016488 biolink:BiologicalProcess farnesol catabolic process The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol. go-plus.json farnesol catabolism|farnesol degradation|farnesol breakdown http://purl.obolibrary.org/obo/GO_0016488 GO:0016489 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016489 GO:0090462 biolink:BiologicalProcess ornithine homeostasis Any process involved in the maintenance of an internal steady state of ornithine within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090462 GO:0016484 biolink:MolecularActivity obsolete proprotein convertase 2 activator activity OBSOLETE. Required for the maturation and activation of proprotein convertase 2. go-plus.json proprotein convertase 2 activator activity http://purl.obolibrary.org/obo/GO_0016484 GO:0090463 biolink:BiologicalProcess lysine homeostasis Any process involved in the maintenance of an internal steady state of lysine within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090463 GO:0016485 biolink:BiologicalProcess protein processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. go-plus.json protein maturation by peptide bond hydrolysis|protein maturation by peptide bond cleavage|peptidolysis during protein maturation|protein maturation by proteolysis http://purl.obolibrary.org/obo/GO_0016485 goslim_chembl GO:0016486 biolink:BiologicalProcess peptide hormone processing The generation of a mature peptide hormone by posttranslational processing of a prohormone. go-plus.json http://purl.obolibrary.org/obo/GO_0016486 GO:0090460 biolink:BiologicalProcess threonine homeostasis Any process involved in the maintenance of an internal steady state of threonine within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090460 GO:0090461 biolink:BiologicalProcess glutamate homeostasis Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090461 GO:0016487 biolink:BiologicalProcess farnesol metabolic process The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol. go-plus.json farnesol metabolism http://purl.obolibrary.org/obo/GO_0016487 GO:0016480 biolink:BiologicalProcess negative regulation of transcription by RNA polymerase III Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III. go-plus.json inhibition of transcription from RNA polymerase III promoter|negative regulation of transcription from Pol III promoter|down-regulation of transcription from RNA polymerase III promoter|negative regulation of transcription from RNA polymerase III promoter|downregulation of transcription from RNA polymerase III promoter|down regulation of transcription from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_0016480 GO:0090466 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090466 GO:0016481 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016481 GO:0090467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090467 GO:0090464 biolink:BiologicalProcess histidine homeostasis Any process involved in the maintenance of an internal steady state of histidine within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090464 GO:0016482 biolink:BiologicalProcess cytosolic transport The directed movement of substances or organelles within the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0016482 GO:0090465 biolink:BiologicalProcess arginine homeostasis Any process involved in the maintenance of an internal steady state of arginine within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090465 GO:0016483 biolink:MolecularActivity tryptophan hydroxylase activator activity Increases the activity of the enzyme tryptophase hydroxylase. go-plus.json http://purl.obolibrary.org/obo/GO_0016483 GO:1905080 biolink:BiologicalProcess negative regulation of cerebellar neuron development Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development. go-plus.json down regulation of cerebellar neuron development|downregulation of cerebellar neuron development|down-regulation of cerebellar neuron development|inhibition of cerebellar neuron development http://purl.obolibrary.org/obo/GO_1905080 GO:1905081 biolink:BiologicalProcess positive regulation of cerebellar neuron development Any process that activates or increases the frequency, rate or extent of cerebellar neuron development. go-plus.json upregulation of cerebellar neuron development|up regulation of cerebellar neuron development|activation of cerebellar neuron development|up-regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_1905081 GO:0090470 biolink:BiologicalProcess shoot organ boundary specification The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0090470 GO:1905082 biolink:BiologicalProcess regulation of mitochondrial translational elongation Any process that modulates the frequency, rate or extent of mitochondrial translational elongation. go-plus.json regulation of mitochondrial translation elongation http://purl.obolibrary.org/obo/GO_1905082 GO:1905083 biolink:BiologicalProcess negative regulation of mitochondrial translational elongation Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation. go-plus.json down-regulation of mitochondrial translation elongation|negative regulation of mitochondrial translation elongation|downregulation of mitochondrial translation elongation|down-regulation of mitochondrial translational elongation|down regulation of mitochondrial translation elongation|inhibition of mitochondrial translation elongation|downregulation of mitochondrial translational elongation|down regulation of mitochondrial translational elongation|inhibition of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_1905083 GO:1905084 biolink:BiologicalProcess positive regulation of mitochondrial translational elongation Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation. go-plus.json positive regulation of mitochondrial translation elongation|up-regulation of mitochondrial translational elongation|activation of mitochondrial translational elongation|up regulation of mitochondrial translation elongation|upregulation of mitochondrial translation elongation|up regulation of mitochondrial translational elongation|up-regulation of mitochondrial translation elongation|activation of mitochondrial translation elongation|upregulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_1905084 GO:1905085 biolink:BiologicalProcess regulation of bioluminescence Any process that modulates the frequency, rate or extent of bioluminescence. go-plus.json http://purl.obolibrary.org/obo/GO_1905085 GO:1905086 biolink:BiologicalProcess negative regulation of bioluminescence Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence. go-plus.json down regulation of bioluminescence|downregulation of bioluminescence|down-regulation of bioluminescence|inhibition of bioluminescence http://purl.obolibrary.org/obo/GO_1905086 GO:1905087 biolink:BiologicalProcess positive regulation of bioluminescence Any process that activates or increases the frequency, rate or extent of bioluminescence. go-plus.json upregulation of bioluminescence|up regulation of bioluminescence|activation of bioluminescence|up-regulation of bioluminescence http://purl.obolibrary.org/obo/GO_1905087 GO:1905088 biolink:BiologicalProcess positive regulation of synaptonemal complex assembly Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly. go-plus.json upregulation of synaptonemal complex assembly|up-regulation of synaptonemal complex formation|activation of synaptonemal complex formation|up regulation of synaptonemal complex assembly|activation of synaptonemal complex assembly|positive regulation of synaptonemal complex formation|up regulation of synaptonemal complex formation|up-regulation of synaptonemal complex assembly|upregulation of synaptonemal complex formation http://purl.obolibrary.org/obo/GO_1905088 GO:1905089 biolink:BiologicalProcess regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization. go-plus.json regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1905089 GO:0090479 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090479 GO:0016499 biolink:MolecularActivity orexin receptor activity Combining with orexin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016499 GO:0016495 biolink:MolecularActivity C-X3-C chemokine receptor activity Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif. go-plus.json http://purl.obolibrary.org/obo/GO_0016495 GO:0090473 biolink:BiologicalProcess lys-arg specific dibasic protein processing Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090473 GO:0090474 biolink:BiologicalProcess arg-arg specific dibasic protein processing Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090474 GO:0016496 biolink:MolecularActivity substance P receptor activity Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016496 GO:0090471 biolink:MolecularActivity 9,15,9'-tri-cis-zeta-carotene isomerase activity Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene. go-plus.json 9,15,9'-tricis-zeta-carotene cis-trans-isomerase http://purl.obolibrary.org/obo/GO_0090471 GO:0016497 biolink:MolecularActivity substance K receptor activity Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity. go-plus.json neuromedin L receptor activity|neurokinin A receptor activity http://purl.obolibrary.org/obo/GO_0016497 GO:0090472 biolink:BiologicalProcess dibasic protein processing Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090472 GO:0016498 biolink:MolecularActivity neuromedin K receptor activity Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity. go-plus.json neurokinin B receptor activity http://purl.obolibrary.org/obo/GO_0016498 GO:0016491 biolink:MolecularActivity oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Reactome:R-HSA-8936442|Reactome:R-HSA-8878581|Reactome:R-HSA-9024624|Reactome:R-HSA-9024630|EC:1.-.-.-|Reactome:R-HSA-9027033|Reactome:R-HSA-3095889|Reactome:R-HSA-9020249|Reactome:R-HSA-9020260|Reactome:R-HSA-5662660|Reactome:R-HSA-9026917|Reactome:R-HSA-1614362|Reactome:R-HSA-9693722|Reactome:R-HSA-9025007|Reactome:R-HSA-9026001|Reactome:R-HSA-209921|Reactome:R-HSA-390438|Reactome:R-HSA-390425|Reactome:R-HSA-209960 go-plus.json redox activity|oxidoreductase activity, acting on other substrates http://purl.obolibrary.org/obo/GO_0016491 goslim_generic|goslim_chembl|goslim_mouse|goslim_candida|goslim_yeast|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics GO:0090477 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090477 GO:0090478 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090478 GO:0016492 biolink:MolecularActivity G protein-coupled neurotensin receptor activity Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state. go-plus.json G protein coupled neurotensin receptor activity|neurotensin receptor activity, G-protein coupled|neurotensin receptor activity, G protein coupled|G-protein coupled neurotensin receptor activity http://purl.obolibrary.org/obo/GO_0016492 GO:0090475 biolink:BiologicalProcess lys-lys specific dibasic protein processing Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090475 GO:0016493 biolink:MolecularActivity C-C chemokine receptor activity Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif. go-plus.json http://purl.obolibrary.org/obo/GO_0016493 GO:0090476 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090476 GO:0016494 biolink:MolecularActivity C-X-C chemokine receptor activity Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif. go-plus.json http://purl.obolibrary.org/obo/GO_0016494 CHEBI:90151 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90151 chebi_ph7_3 CHEBI:65190 biolink:ChemicalSubstance first generation antipsychotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_65190 UBERON:0018261 biolink:AnatomicalEntity muscular coat of digestive tract A muscular coat that is part of a digestive tract. go-plus.json muscular layer of digestive tract|tunica externa of digestive tract|muscularis externa of digestive tract|tunica muscularis of digestive tract http://purl.obolibrary.org/obo/UBERON_0018261 CHEBI:65191 biolink:ChemicalSubstance second generation antipsychotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_65191 PR:000003171 biolink:Protein IGFBP-related protein go-plus.json http://purl.obolibrary.org/obo/PR_000003171 PR:000003172 biolink:Protein connective tissue growth factor An IGFBP-related protein that is a translation product of the human CTGF gene or a 1:1 ortholog thereof. go-plus.json insulin-like growth factor-binding protein 8|HCS24|protein FISP-12|CTGF|Fisp-12|IBP-8|IGFBP-8|CCN2|IGFBP8|Fisp12|IGF-binding protein 8|hypertrophic chondrocyte-specific protein 24|CCN family member 2 http://purl.obolibrary.org/obo/PR_000003172 CHEBI:16218 biolink:ChemicalSubstance beta-D-glucose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16218 CHEBI:16219 biolink:ChemicalSubstance cucurbitacin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16219 CHEBI:16216 biolink:ChemicalSubstance 3-(acetamidomethylidene)-2-(hydroxymethyl)succinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16216 CHEBI:16217 biolink:ChemicalSubstance D-glucono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16217 chebi_ph7_3 CHEBI:16214 biolink:ChemicalSubstance dolichyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16214 CHEBI:16215 biolink:ChemicalSubstance phosphonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16215 chebi_ph7_3 CHEBI:90157 biolink:ChemicalSubstance 2-methylhexenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90157 chebi_ph7_3 UBERON:0018260 biolink:AnatomicalEntity layer of muscle tissue Any organ component layer that consists of muscle tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018260 CHEBI:90158 biolink:ChemicalSubstance N-carbamoylaspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90158 chebi_ph7_3 CHEBI:16213 biolink:ChemicalSubstance coformycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16213 CHEBI:90159 biolink:ChemicalSubstance geranyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90159 CHEBI:16210 biolink:ChemicalSubstance sinapoyltartronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16210 CHEBI:16211 biolink:ChemicalSubstance cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16211 CHEBI:90153 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90153 chebi_ph7_3 CHEBI:90156 biolink:ChemicalSubstance 2-methylhexanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90156 chebi_ph7_3 UBERON:0018256 biolink:AnatomicalEntity lacrimal vein A vein that drains a lacrimal gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018256 UBERON:0018257 biolink:AnatomicalEntity submucosa of digestive tract Any portion of submucosa that lines the digestive tract. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018257 UBERON:0018254 biolink:AnatomicalEntity skeletal musculature go-plus.json http://purl.obolibrary.org/obo/UBERON_0018254 UBERON:0018251 biolink:AnatomicalEntity meningeal vein One of the veins draining a meninix. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018251 CHEBI:16209 biolink:ChemicalSubstance hypotaurocyamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16209 CHEBI:16207 biolink:ChemicalSubstance 3-hydroxybenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16207 chebi_ph7_3 CHEBI:16208 biolink:ChemicalSubstance 3-mercaptopyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16208 CHEBI:16205 biolink:ChemicalSubstance biphenyl-2,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16205 chebi_ph7_3 CHEBI:16206 biolink:ChemicalSubstance sn-3-O-(geranylgeranyl)glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16206 CHEBI:16204 biolink:ChemicalSubstance phloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16204 chebi_ph7_3 CHEBI:16200 biolink:ChemicalSubstance questin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16200 CHEBI:90143 biolink:ChemicalSubstance N-amidinoaspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90143 GO:2000409 biolink:BiologicalProcess positive regulation of T cell extravasation Any process that activates or increases the frequency, rate or extent of T cell extravasation. go-plus.json positive regulation of T lymphocyte extravasation|positive regulation of T-cell extravasation|positive regulation of T-lymphocyte extravasation http://purl.obolibrary.org/obo/GO_2000409 CHEBI:90171 biolink:ChemicalSubstance 2-hydro-beta-NAD go-plus.json http://purl.obolibrary.org/obo/CHEBI_90171 UBERON:0018246 biolink:AnatomicalEntity thyroid vein A vein that drains a thyroid gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018246 CHEBI:90172 biolink:ChemicalSubstance c-Jun N-terminal kinase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_90172 NCBITaxon:186817 biolink:OrganismalEntity Bacillaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_186817 UBERON:0018243 biolink:AnatomicalEntity thymic artery A vein that supplies blood to the thymus. go-plus.json thymic arteries|thymic branch of internal thoracic artery http://purl.obolibrary.org/obo/UBERON_0018243 CHEBI:90173 biolink:ChemicalSubstance 6-hydro-beta-NADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_90173 CHEBI:90174 biolink:ChemicalSubstance 6-hydro-beta-NAD go-plus.json http://purl.obolibrary.org/obo/CHEBI_90174 CHEBI:90170 biolink:ChemicalSubstance 2-hydro-beta-NADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_90170 GO:2000401 biolink:BiologicalProcess regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of lymphocyte migration. go-plus.json http://purl.obolibrary.org/obo/GO_2000401 GO:2000402 biolink:BiologicalProcess negative regulation of lymphocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. go-plus.json http://purl.obolibrary.org/obo/GO_2000402 CHEBI:31832 biolink:ChemicalSubstance methyl salicylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31832 chebi_ph7_3 GO:2000403 biolink:BiologicalProcess positive regulation of lymphocyte migration Any process that activates or increases the frequency, rate or extent of lymphocyte migration. go-plus.json http://purl.obolibrary.org/obo/GO_2000403 GO:2000404 biolink:BiologicalProcess regulation of T cell migration Any process that modulates the frequency, rate or extent of T cell migration. go-plus.json regulation of T lymphocyte migration|regulation of T-cell migration|regulation of T-lymphocyte migration http://purl.obolibrary.org/obo/GO_2000404 GO:2000405 biolink:BiologicalProcess negative regulation of T cell migration Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. go-plus.json negative regulation of T-cell migration|negative regulation of T-lymphocyte migration|negative regulation of T lymphocyte migration http://purl.obolibrary.org/obo/GO_2000405 GO:2000406 biolink:BiologicalProcess positive regulation of T cell migration Any process that activates or increases the frequency, rate or extent of T cell migration. go-plus.json positive regulation of T-cell migration|positive regulation of T-lymphocyte migration|positive regulation of T lymphocyte migration http://purl.obolibrary.org/obo/GO_2000406 GO:2000407 biolink:BiologicalProcess regulation of T cell extravasation Any process that modulates the frequency, rate or extent of T cell extravasation. go-plus.json regulation of T-cell extravasation|regulation of T-lymphocyte extravasation|regulation of T lymphocyte extravasation http://purl.obolibrary.org/obo/GO_2000407 UBERON:0018247 biolink:AnatomicalEntity cervical thymic artery An artery that supplies a cervical thymus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018247 GO:2000408 biolink:BiologicalProcess negative regulation of T cell extravasation Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation. go-plus.json negative regulation of T lymphocyte extravasation|negative regulation of T-cell extravasation|negative regulation of T-lymphocyte extravasation http://purl.obolibrary.org/obo/GO_2000408 CHEBI:16238 biolink:ChemicalSubstance FAD go-plus.json http://purl.obolibrary.org/obo/CHEBI_16238 CHEBI:16239 biolink:ChemicalSubstance benzyl (2R,3S)-3-hydroxy-2-methylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16239 chebi_ph7_3 CHEBI:16236 biolink:ChemicalSubstance ethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16236 chebi_ph7_3 GO:2000400 biolink:BiologicalProcess positive regulation of thymocyte aggregation Any process that activates or increases the frequency, rate or extent of thymocyte aggregation. go-plus.json positive regulation of immature T cell aggregation|positive regulation of thymic lymphocyte aggregation|positive regulation of T cell precursor aggregation|positive regulation of immature T-lymphocyte aggregation|positive regulation of immature T-cell aggregation http://purl.obolibrary.org/obo/GO_2000400 CHEBI:16237 biolink:ChemicalSubstance 4-chlorophenylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16237 chebi_ph7_3 CHEBI:16234 biolink:ChemicalSubstance hydroxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16234 CHEBI:16235 biolink:ChemicalSubstance guanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16235 chebi_ph7_3 CHEBI:16232 biolink:ChemicalSubstance N(6)-acyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16232 CHEBI:16233 biolink:ChemicalSubstance (S)-cheilanthifoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16233 chebi_ph7_3 CHEBI:16230 biolink:ChemicalSubstance 5-hydroxypentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16230 chebi_ph7_3 CHEBI:16231 biolink:ChemicalSubstance cis-4-hydroxy-D-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16231 CHEBI:90176 biolink:ChemicalSubstance 2,5-dihydroxybenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90176 UBERON:0018234 biolink:AnatomicalEntity stroma of pancreas A stroma that is part of a pancreas. go-plus.json pancreatic stroma http://purl.obolibrary.org/obo/UBERON_0018234 UBERON:0018235 biolink:AnatomicalEntity capsule of pancreas A capsule that divides the parenchyma of the pancreas into lobes and lobules go-plus.json pancreatic capsule http://purl.obolibrary.org/obo/UBERON_0018235 UBERON:0018232 biolink:AnatomicalEntity axillary sweat gland A sweat gland that is part of a axilla. go-plus.json axillary apocrine sweat gland|sweat gland of axilla http://purl.obolibrary.org/obo/UBERON_0018232 CHEBI:90162 biolink:ChemicalSubstance 2,3-epoxy-2,3-dihydrobenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90162 CHEBI:90163 biolink:ChemicalSubstance beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90163 chebi_ph7_3 GO:2000412 biolink:BiologicalProcess positive regulation of thymocyte migration Any process that activates or increases the frequency, rate or extent of thymocyte migration. go-plus.json positive regulation of immature T cell migration|positive regulation of thymic lymphocyte migration|positive regulation of immature T lymphocyte migration|positive regulation of immature T-cell migration|positive regulation of immature T-lymphocyte migration http://purl.obolibrary.org/obo/GO_2000412 GO:2000413 biolink:BiologicalProcess regulation of fibronectin-dependent thymocyte migration Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration. go-plus.json regulation of fibronectin-dependent immature T cell migration|regulation of fibronectin-dependent thymic lymphocyte migration|regulation of fibronectin-dependent immature T lymphocyte migration|regulation of fibronectin-dependent immature T-cell migration|regulation of fibronectin-dependent immature T-lymphocyte migration http://purl.obolibrary.org/obo/GO_2000413 GO:2000414 biolink:BiologicalProcess negative regulation of fibronectin-dependent thymocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration. go-plus.json negative regulation of fibronectin-dependent immature T-cell migration|negative regulation of fibronectin-dependent immature T-lymphocyte migration|negative regulation of fibronectin-dependent immature T cell migration|negative regulation of fibronectin-dependent thymic lymphocyte migration|negative regulation of fibronectin-dependent immature T lymphocyte migration http://purl.obolibrary.org/obo/GO_2000414 GO:2000415 biolink:BiologicalProcess positive regulation of fibronectin-dependent thymocyte migration Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration. go-plus.json positive regulation of fibronectin-dependent immature T-cell migration|positive regulation of fibronectin-dependent immature T-lymphocyte migration|positive regulation of fibronectin-dependent immature T cell migration|positive regulation of fibronectin-dependent thymic lymphocyte migration|positive regulation of fibronectin-dependent immature T lymphocyte migration http://purl.obolibrary.org/obo/GO_2000415 GO:2000416 biolink:BiologicalProcess regulation of eosinophil migration Any process that modulates the frequency, rate or extent of eosinophil migration. go-plus.json http://purl.obolibrary.org/obo/GO_2000416 UBERON:0018238 biolink:AnatomicalEntity dorsal column nucleus A nucleus that contain secondary neurons of the dorsal column-medial lemniscus pathway, which carries fine touch and proprioceptive information from the body to the brain. Examples: gracile nucleus, cuneat nucleus, nucleus of Bishoff. go-plus.json dorsal column nuclei http://purl.obolibrary.org/obo/UBERON_0018238 UBERON:0018239 biolink:AnatomicalEntity rhombomere boundary A boundary delimiting a rhombomere. go-plus.json rhombomere junction http://purl.obolibrary.org/obo/UBERON_0018239 GO:2000417 biolink:BiologicalProcess negative regulation of eosinophil migration Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration. go-plus.json http://purl.obolibrary.org/obo/GO_2000417 GO:2000418 biolink:BiologicalProcess positive regulation of eosinophil migration Any process that activates or increases the frequency, rate or extent of eosinophil migration. go-plus.json http://purl.obolibrary.org/obo/GO_2000418 UBERON:0018237 biolink:AnatomicalEntity dorsal column-medial lemniscus pathway A sensory tract originating in the spinal cord responsible for transmitting fine touch, vibration and conscious proprioceptive information from the body to the cerebral cortex. The components include the fasciculus gracilis and fasciculus cuneatus. go-plus.json DCML pathway|dorsal column-medial lemniscus tract|posterior column pathway|dorsal column|DCML|dorsal column-medial lemniscus pathway|dorsal column-medial lemniscus system|medial lemniscus tracts|posterior column-medial lemniscus system|dorsal column tract|posterior column/medial leminscus pathway|posterior column-medial leminscus pathway http://purl.obolibrary.org/obo/UBERON_0018237 GO:2000419 biolink:BiologicalProcess regulation of eosinophil extravasation Any process that modulates the frequency, rate or extent of eosinophil extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000419 CHEBI:16229 biolink:ChemicalSubstance 3beta-hydroxy-5beta-pregnan-20-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16229 chebi_ph7_3 CHEBI:16227 biolink:ChemicalSubstance pyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16227 chebi_ph7_3 CHEBI:16228 biolink:ChemicalSubstance 2,2-dialkylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16228 GO:2000410 biolink:BiologicalProcess regulation of thymocyte migration Any process that modulates the frequency, rate or extent of thymocyte migration. go-plus.json regulation of thymic lymphocyte migration|regulation of immature T lymphocyte migration|regulation of immature T-cell migration|regulation of immature T-lymphocyte migration|regulation of immature T cell migration http://purl.obolibrary.org/obo/GO_2000410 CHEBI:16225 biolink:ChemicalSubstance S-formylglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16225 GO:2000411 biolink:BiologicalProcess negative regulation of thymocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration. go-plus.json negative regulation of immature T-lymphocyte migration|negative regulation of immature T cell migration|negative regulation of thymic lymphocyte migration|negative regulation of immature T lymphocyte migration|negative regulation of immature T-cell migration http://purl.obolibrary.org/obo/GO_2000411 CHEBI:16226 biolink:ChemicalSubstance limonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16226 chebi_ph7_3 CHEBI:16223 biolink:ChemicalSubstance dimethylarsinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16223 chebi_ph7_3 NCBITaxon:186801 biolink:OrganismalEntity Clostridia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_186801 CHEBI:16224 biolink:ChemicalSubstance alpha-D-mannopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16224 CHEBI:16221 biolink:ChemicalSubstance sn-glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16221 CHEBI:16222 biolink:ChemicalSubstance D-galacto-hexodialdose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16222 chebi_ph7_3 CHEBI:90164 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90164 chebi_ph7_3 CHEBI:16220 biolink:ChemicalSubstance coniferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16220 chebi_ph7_3 CHEBI:90165 biolink:ChemicalSubstance N-hexanoylphytosphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90165 NCBITaxon:186802 biolink:OrganismalEntity Eubacteriales go-plus.json Clostridiales http://purl.obolibrary.org/obo/NCBITaxon_186802 CHEBI:90167 biolink:ChemicalSubstance dTDP-2,3-dehydro-2,6-dideoxy-4-keto-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_90167 IAO:0000428 biolink:OntologyClass requires discussion A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. go-plus.json http://purl.obolibrary.org/obo/IAO_0000428 GO:0090404 biolink:CellularComponent pollen tube tip The region at growing end of the pollen tube cell, where polarized growth occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0090404 GO:0090405 biolink:CellularComponent unicellular trichome branch A cell projection part that is a branch of a unicellular trichome. go-plus.json http://purl.obolibrary.org/obo/GO_0090405 GO:0090402 biolink:BiologicalProcess oncogene-induced cell senescence A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family. go-plus.json OIS http://purl.obolibrary.org/obo/GO_0090402 GO:0090403 biolink:BiologicalProcess oxidative stress-induced premature senescence A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0090403 GO:0090408 biolink:BiologicalProcess phloem nitrate loading The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink. go-plus.json http://purl.obolibrary.org/obo/GO_0090408 GO:0090409 biolink:MolecularActivity malonyl-CoA synthetase activity Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate. MetaCyc:RXN-12359|EC:6.2.1.n3|RHEA:32139 go-plus.json http://purl.obolibrary.org/obo/GO_0090409 GO:0090406 biolink:CellularComponent pollen tube A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain. go-plus.json http://purl.obolibrary.org/obo/GO_0090406 GO:0090407 biolink:BiologicalProcess organophosphate biosynthetic process The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. go-plus.json http://purl.obolibrary.org/obo/GO_0090407 GO:0090400 biolink:BiologicalProcess stress-induced premature senescence A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays. go-plus.json SIPS http://purl.obolibrary.org/obo/GO_0090400 GO:0090401 biolink:BiologicalProcess obsolete viral-induced premature senescence OBSOLETE. A cellular senescence process associated with the dismantling of a cell as a response to viral infection. go-plus.json http://purl.obolibrary.org/obo/GO_0090401 GO:0090415 biolink:MolecularActivity 7-hydroxymethyl chlorophyll a reductase activity Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0090415 GO:0090416 biolink:MolecularActivity nicotinate transmembrane transporter activity Enables the transfer of nicotinate from one side of a membrane to the other. Reactome:R-HSA-8869603 go-plus.json http://purl.obolibrary.org/obo/GO_0090416 GO:0090413 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process. go-plus.json negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0090413 GO:0090414 biolink:BiologicalProcess molybdate ion export from vacuole The directed movement of molybdate ions out of the vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0090414 GO:0090419 biolink:BiologicalProcess negative regulation of transcription involved in G2/M transition of mitotic cell cycle Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle. go-plus.json negative regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|down-regulation of transcription from RNA polymerase II promoter during the G2/M transition of the mitotic cell cycle http://purl.obolibrary.org/obo/GO_0090419 GO:0090417 biolink:MolecularActivity N-methylnicotinate transmembrane transporter activity Enables the transfer of N-methylnicotinate from one side of a membrane to the other. go-plus.json N-methylnicotinate transporter activity http://purl.obolibrary.org/obo/GO_0090417 GO:0090418 biolink:BiologicalProcess obsolete positive regulation of transcription involved in S-phase of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the S phase of the mitotic cell cycle. go-plus.json activation of transcription involved in S phase of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|up-regulation of S phase specific transcription in the mitotic cell cycle|positive regulation of transcription involved in S-phase of mitotic cell cycle|up-regulation of transcription involved in S phase of mitotic cell cycle|activation of S phase specific transcription in the mitotic cell cycle|positive regulation of S phase specific transcription in the mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle http://purl.obolibrary.org/obo/GO_0090418 NCBITaxon:186820 biolink:OrganismalEntity Listeriaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_186820 NCBITaxon:186826 biolink:OrganismalEntity Lactobacillales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_186826 GO:0090411 biolink:MolecularActivity brassinosteroid binding Binding to a brassinosteroid. go-plus.json http://purl.obolibrary.org/obo/GO_0090411 GO:0090412 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process. go-plus.json positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0090412 GO:0090410 biolink:BiologicalProcess malonate catabolic process The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion. go-plus.json http://purl.obolibrary.org/obo/GO_0090410 CHEBI:90189 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90189 chebi_ph7_3 OBO:uberon/core#conduit_for biolink:OntologyClass conduit for x is a conduit for y iff y passes through the lumen of x. conduit_for go-plus.json http://purl.obolibrary.org/obo/uberon/core#conduit_for UBERON:0018278 biolink:AnatomicalEntity epidermal egg tooth Epidermal outgrowth that facilitates breaking of the eggshell in archosaurs and monotremes. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018278 UBERON:0018276 biolink:AnatomicalEntity egg tooth A protuberence or true tooth that is used during hatching to break the eggshell. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018276 GO:1905000 biolink:BiologicalProcess regulation of membrane repolarization during atrial cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. go-plus.json regulation of electrocardiogram QRS complex|regulation of atrial repolarization http://purl.obolibrary.org/obo/GO_1905000 GO:1905001 biolink:BiologicalProcess negative regulation of membrane repolarization during atrial cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. go-plus.json down regulation of electrocardiogram QRS complex|downregulation of membrane repolarization during atrial cardiac muscle cell action potential|negative regulation of atrial repolarization|downregulation of electrocardiogram QRS complex|down-regulation of atrial repolarization|down regulation of membrane repolarization during atrial cardiac muscle cell action potential|inhibition of membrane repolarization during atrial cardiac muscle cell action potential|negative regulation of electrocardiogram QRS complex|down-regulation of electrocardiogram QRS complex|inhibition of atrial repolarization|down regulation of atrial repolarization|inhibition of electrocardiogram QRS complex|down-regulation of membrane repolarization during atrial cardiac muscle cell action potential|downregulation of atrial repolarization http://purl.obolibrary.org/obo/GO_1905001 GO:1905002 biolink:BiologicalProcess positive regulation of membrane repolarization during atrial cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. go-plus.json up regulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of atrial repolarization|activation of atrial repolarization|up regulation of electrocardiogram QRS complex|upregulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of electrocardiogram QRS complex|up-regulation of atrial repolarization|activation of electrocardiogram QRS complex|up-regulation of membrane repolarization during atrial cardiac muscle cell action potential|activation of membrane repolarization during atrial cardiac muscle cell action potential|upregulation of atrial repolarization|up-regulation of electrocardiogram QRS complex|upregulation of electrocardiogram QRS complex|up regulation of atrial repolarization http://purl.obolibrary.org/obo/GO_1905002 GO:1905003 biolink:BiologicalProcess picolinic acid metabolic process The chemical reactions and pathways involving picolinic acid. go-plus.json picolinic acid metabolism|picolinate metabolism http://purl.obolibrary.org/obo/GO_1905003 OBO:GOCHE_22676 biolink:OntologyClass substance with auxin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_22676 3_STAR CHEBI:16182 biolink:ChemicalSubstance 2-methylbutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_16182 chebi_ph7_3 CHEBI:16183 biolink:ChemicalSubstance methane go-plus.json http://purl.obolibrary.org/obo/CHEBI_16183 chebi_ph7_3 CHEBI:16180 biolink:ChemicalSubstance N-acylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16180 CHEBI:16181 biolink:ChemicalSubstance 1-amino-1-deoxy-scyllo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16181 GO:2000467 biolink:BiologicalProcess positive regulation of glycogen (starch) synthase activity Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity. go-plus.json positive regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|positive regulation of UDP-glucose-glycogen glucosyltransferase activity|positive regulation of UDP-glycogen synthase activity|positive regulation of UDPG-glycogen transglucosylase activity|positive regulation of glycogen (starch) synthetase activity|positive regulation of UDPG-glycogen synthetase activity http://purl.obolibrary.org/obo/GO_2000467 CHEBI:65113 biolink:ChemicalSubstance 5''-phosphoribostamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_65113 GO:2000468 biolink:BiologicalProcess regulation of peroxidase activity Any process that modulates the frequency, rate or extent of peroxidase activity. go-plus.json regulation of oxyperoxidase activity|regulation of donor:hydrogen-peroxide oxidoreductase activity|regulation of peroxidase reaction http://purl.obolibrary.org/obo/GO_2000468 CHEBI:65114 biolink:ChemicalSubstance 2-oxo-3-(5-oxofuran-2-ylidene)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65114 GO:2000469 biolink:BiologicalProcess negative regulation of peroxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity. go-plus.json negative regulation of donor:hydrogen-peroxide oxidoreductase activity|negative regulation of peroxidase reaction|negative regulation of oxyperoxidase activity http://purl.obolibrary.org/obo/GO_2000469 CHEBI:65115 biolink:ChemicalSubstance 3-oxoicosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65115 chebi_ph7_3 CHEBI:65116 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,polycis-decaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_65116 CHEBI:65110 biolink:ChemicalSubstance butirosin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_65110 CHEBI:65111 biolink:ChemicalSubstance 3-substituted propionyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65111 chebi_ph7_3 UBERON:0018303 biolink:AnatomicalEntity adrenal tissue Tissue that is part of some adrenal gland go-plus.json adrenal gland tissue http://purl.obolibrary.org/obo/UBERON_0018303 CHEBI:111544 biolink:ChemicalSubstance 2'-hydroxyrifampicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_111544 CHEBI:135511 biolink:ChemicalSubstance rebeccamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_135511 chebi_ph7_3 GO:2000460 biolink:BiologicalProcess obsolete regulation of eukaryotic cell surface binding OBSOLETE. Any process that modulates the frequency, rate or extent of eukaryotic cell surface binding. go-plus.json regulation of eukaryotic cell surface binding http://purl.obolibrary.org/obo/GO_2000460 UBERON:0008987 biolink:AnatomicalEntity renal parenchyma The functional tissue of the kidney, consisting of the nephrons. go-plus.json kidney parenchyma|parenchyma of kidney http://purl.obolibrary.org/obo/UBERON_0008987 GO:2000461 biolink:BiologicalProcess obsolete negative regulation of eukaryotic cell surface binding OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic cell surface binding. go-plus.json negative regulation of eukaryotic cell surface binding http://purl.obolibrary.org/obo/GO_2000461 GO:2000462 biolink:BiologicalProcess obsolete positive regulation of eukaryotic cell surface binding OBSOLETE. Any process that activates or increases the frequency, rate or extent of eukaryotic cell surface binding. go-plus.json positive regulation of eukaryotic cell surface binding http://purl.obolibrary.org/obo/GO_2000462 UBERON:0008989 biolink:AnatomicalEntity submucosal esophageal gland One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed. go-plus.json mucous gland of submucosa of esophagus|submocosal esophageal gland|glandulae oesophageae|esophageal gland http://purl.obolibrary.org/obo/UBERON_0008989 GO:2000463 biolink:BiologicalProcess positive regulation of excitatory postsynaptic potential Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. go-plus.json positive regulation of EPSP|positive regulation of excitatory post-synaptic membrane potential http://purl.obolibrary.org/obo/GO_2000463 CHEBI:65117 biolink:ChemicalSubstance CDP-N,N-dimethylethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65117 chebi_ph7_3 CHEBI:65118 biolink:ChemicalSubstance C20 3-dehydrosphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65118 GO:2000464 biolink:BiologicalProcess positive regulation of astrocyte chemotaxis Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000464 GO:2000465 biolink:BiologicalProcess regulation of glycogen (starch) synthase activity Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity. go-plus.json regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|regulation of UDPG-glycogen transglucosylase activity|regulation of glycogen (starch) synthetase activity|regulation of UDPG-glycogen synthetase activity|regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of UDP-glycogen synthase activity|regulation of UDP-glucose-glycogen glucosyltransferase activity http://purl.obolibrary.org/obo/GO_2000465 CHEBI:111542 biolink:ChemicalSubstance validone go-plus.json http://purl.obolibrary.org/obo/CHEBI_111542 chebi_ph7_3 GO:2000466 biolink:BiologicalProcess negative regulation of glycogen (starch) synthase activity Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity. go-plus.json negative regulation of UDPG-glycogen synthetase activity|negative regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of UDP-glucose-glycogen glucosyltransferase activity|negative regulation of UDP-glycogen synthase activity|negative regulation of UDPG-glycogen transglucosylase activity|negative regulation of glycogen (starch) synthetase activity|negative regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity http://purl.obolibrary.org/obo/GO_2000466 CHEBI:16179 biolink:ChemicalSubstance retinyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_16179 chebi_ph7_3 CHEBI:16177 biolink:ChemicalSubstance vicianose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16177 chebi_ph7_3 CHEBI:16175 biolink:ChemicalSubstance cholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16175 chebi_ph7_3 CHEBI:16176 biolink:ChemicalSubstance D-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16176 CHEBI:16173 biolink:ChemicalSubstance aldehydo-N-acyl-D-mannosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16173 CHEBI:16174 biolink:ChemicalSubstance dADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16174 CHEBI:16171 biolink:ChemicalSubstance NMN zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_16171 CHEBI:16172 biolink:ChemicalSubstance neryl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16172 CHEBI:16170 biolink:ChemicalSubstance mercury(0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16170 chebi_ph7_3 GO:2000478 biolink:BiologicalProcess positive regulation of metanephric glomerular visceral epithelial cell development Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. go-plus.json positive regulation of metanephric podocyte development http://purl.obolibrary.org/obo/GO_2000478 GO:2000479 biolink:BiologicalProcess regulation of cAMP-dependent protein kinase activity Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity. go-plus.json regulation of PKA|regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|regulation of 3',5' cAMP-dependent protein kinase activity|regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|regulation of 3',5'-cAMP-dependent protein kinase activity|regulation of protein kinase A activity|regulation of AMPK|regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|regulation of STK22|regulation of cyclic AMP-dependent protein kinase activity|regulation of PKA C http://purl.obolibrary.org/obo/GO_2000479 CHEBI:41131 biolink:ChemicalSubstance crotonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41131 CHEBI:65121 biolink:ChemicalSubstance isopentenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_65121 CHEBI:65122 biolink:ChemicalSubstance 3-substituted propionyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65122 GO:2000470 biolink:BiologicalProcess positive regulation of peroxidase activity Any process that activates or increases the frequency, rate or extent of peroxidase activity. go-plus.json positive regulation of oxyperoxidase activity|positive regulation of donor:hydrogen-peroxide oxidoreductase activity|positive regulation of peroxidase reaction http://purl.obolibrary.org/obo/GO_2000470 GO:2000471 biolink:BiologicalProcess regulation of hematopoietic stem cell migration Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration. go-plus.json regulation of hemopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 GO:2000472 biolink:BiologicalProcess negative regulation of hematopoietic stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration. go-plus.json negative regulation of hemopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000472 GO:2000473 biolink:BiologicalProcess positive regulation of hematopoietic stem cell migration Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration. go-plus.json positive regulation of hemopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000473 GO:2000474 biolink:BiologicalProcess regulation of opioid receptor signaling pathway Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway. go-plus.json regulation of opioid receptor signalling pathway http://purl.obolibrary.org/obo/GO_2000474 CHEBI:41139 biolink:ChemicalSubstance N,N,N-trimethylglycinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_41139 GO:2000475 biolink:BiologicalProcess negative regulation of opioid receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway. go-plus.json negative regulation of opioid receptor signalling pathway http://purl.obolibrary.org/obo/GO_2000475 GO:2000476 biolink:BiologicalProcess positive regulation of opioid receptor signaling pathway Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway. go-plus.json positive regulation of opioid receptor signalling pathway http://purl.obolibrary.org/obo/GO_2000476 GO:2000477 biolink:BiologicalProcess regulation of metanephric glomerular visceral epithelial cell development Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. go-plus.json regulation of metanephric podocyte development http://purl.obolibrary.org/obo/GO_2000477 CHEBI:16168 biolink:ChemicalSubstance 6-hydroxynicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16168 OIO:hasRelatedSynonym biolink:OntologyClass has_related_synonym go-plus.json http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym CHEBI:16169 biolink:ChemicalSubstance homogentisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16169 chebi_ph7_3 CHEBI:16166 biolink:ChemicalSubstance 2-caffeoylisocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16166 CHEBI:16164 biolink:ChemicalSubstance pyrogallol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16164 chebi_ph7_3 CHEBI:16165 biolink:ChemicalSubstance D-glucono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16165 chebi_ph7_3 CHEBI:16162 biolink:ChemicalSubstance o-orsellinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16162 chebi_ph7_3 CHEBI:16163 biolink:ChemicalSubstance S-carboxymethyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16163 GO:2000489 biolink:BiologicalProcess regulation of hepatic stellate cell activation Any process that modulates the frequency, rate or extent of hepatic stellate cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000489 CHEBI:65136 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65136 CHEBI:65131 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65131 CHEBI:65132 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65132 GO:2000481 biolink:BiologicalProcess positive regulation of cAMP-dependent protein kinase activity Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity. go-plus.json positive regulation of cyclic AMP-dependent protein kinase activity|positive regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|positive regulation of 3',5' cAMP-dependent protein kinase activity|positive regulation of protein kinase A activity|positive regulation of STK22|positive regulation of PKA C|positive regulation of PKA|positive regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|positive regulation of 3',5'-cAMP-dependent protein kinase activity|positive regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|positive regulation of AMPK http://purl.obolibrary.org/obo/GO_2000481 GO:2000482 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000482 GO:2000483 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000483 GO:2000484 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000484 CHEBI:65139 biolink:ChemicalSubstance (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65139 GO:2000485 biolink:BiologicalProcess regulation of glutamine transport Any process that modulates the frequency, rate or extent of glutamine transport. go-plus.json regulation of L-glutamine transport http://purl.obolibrary.org/obo/GO_2000485 GO:2000486 biolink:BiologicalProcess negative regulation of glutamine transport Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport. go-plus.json negative regulation of L-glutamine transport http://purl.obolibrary.org/obo/GO_2000486 UBERON:0008969 biolink:AnatomicalEntity dental follicle A sac containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively. go-plus.json dental sac|tooth follicle http://purl.obolibrary.org/obo/UBERON_0008969 GO:2000487 biolink:BiologicalProcess positive regulation of glutamine transport Any process that activates or increases the frequency, rate or extent of glutamine transport. go-plus.json positive regulation of L-glutamine transport http://purl.obolibrary.org/obo/GO_2000487 GO:2000488 biolink:BiologicalProcess positive regulation of brassinosteroid biosynthetic process Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process. go-plus.json positive regulation of brassinosteroid synthesis|positive regulation of brassinosteroid formation|positive regulation of brassinosteroid biosynthesis|positive regulation of brassinosteroid anabolism http://purl.obolibrary.org/obo/GO_2000488 CHEBI:16199 biolink:ChemicalSubstance urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_16199 chebi_ph7_3 CHEBI:16197 biolink:ChemicalSubstance N-acylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16197 UBERON:0008962 biolink:AnatomicalEntity forelimb bone A bone that is part of a forelimb region. Examples: humerus, any of the phalanges. Counter-example: scapula (a bone of the pectoral girdle). Note that we consider the forelimb to end at the shoulder. go-plus.json wing bone|free forelimb bone http://purl.obolibrary.org/obo/UBERON_0008962 GO:2000480 biolink:BiologicalProcess negative regulation of cAMP-dependent protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity. go-plus.json negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|negative regulation of 3',5' cAMP-dependent protein kinase activity|negative regulation of protein kinase A activity|negative regulation of STK22|negative regulation of PKA C|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|negative regulation of PKA|negative regulation of 3',5'-cAMP-dependent protein kinase activity|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|negative regulation of AMPK|negative regulation of cyclic AMP-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_2000480 CHEBI:16196 biolink:ChemicalSubstance oleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16196 CHEBI:16193 biolink:ChemicalSubstance 3-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16193 chebi_ph7_3 CHEBI:16192 biolink:ChemicalSubstance 2'-deoxyguanosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16192 CHEBI:16190 biolink:ChemicalSubstance cis-cyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16190 chebi_ph7_3 CHEBI:80774 biolink:ChemicalSubstance tauroursodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80774 GO:2000492 biolink:BiologicalProcess regulation of interleukin-18-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway. go-plus.json regulation of interleukin-18-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000492 GO:2000493 biolink:BiologicalProcess negative regulation of interleukin-18-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway. go-plus.json negative regulation of interleukin-18-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000493 GO:2000494 biolink:BiologicalProcess positive regulation of interleukin-18-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway. go-plus.json positive regulation of interleukin-18-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000494 GO:2000495 biolink:BiologicalProcess regulation of cell proliferation involved in compound eye morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000495 GO:2000496 biolink:BiologicalProcess negative regulation of cell proliferation involved in compound eye morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000496 CHEBI:41117 biolink:ChemicalSubstance N-benzylformamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_41117 chebi_ph7_3 GO:2000497 biolink:BiologicalProcess positive regulation of cell proliferation involved in compound eye morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000497 GO:2000498 biolink:BiologicalProcess obsolete regulation of induction of apoptosis in response to chemical stimulus OBSOLETE. Any process that modulates the frequency, rate or extent of induction of apoptosis in response to chemical stimulus. go-plus.json regulation of induction of apoptosis in response to chemical stimulus|regulation of induction of apoptosis in response to chemical substance http://purl.obolibrary.org/obo/GO_2000498 GO:2000499 biolink:BiologicalProcess obsolete negative regulation of induction of apoptosis in response to chemical stimulus OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of induction of apoptosis in response to chemical stimulus. go-plus.json negative regulation of induction of apoptosis in response to chemical substance|negative regulation of induction of apoptosis in response to chemical stimulus http://purl.obolibrary.org/obo/GO_2000499 CHEBI:16188 biolink:ChemicalSubstance octan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16188 chebi_ph7_3 CHEBI:16189 biolink:ChemicalSubstance sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16189 chebi_ph7_3 CHEBI:16187 biolink:ChemicalSubstance 1-piperideine-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16187 GO:2000490 biolink:BiologicalProcess negative regulation of hepatic stellate cell activation Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000490 CHEBI:16184 biolink:ChemicalSubstance 7-O-acetylsalutaridinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16184 CHEBI:16185 biolink:ChemicalSubstance N(5)-acyl-L-ornithine ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_16185 UBERON:0008951 biolink:AnatomicalEntity left lung lobe A lobe of lung that is part of a left lung. go-plus.json lobe of left lung|lobe of the left lung http://purl.obolibrary.org/obo/UBERON_0008951 GO:2000491 biolink:BiologicalProcess positive regulation of hepatic stellate cell activation Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2000491 GO:2000423 biolink:BiologicalProcess negative regulation of eosinophil chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000423 CHEBI:111509 biolink:ChemicalSubstance alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_111509 chebi_ph7_3 GO:2000424 biolink:BiologicalProcess positive regulation of eosinophil chemotaxis Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000424 CHEBI:80788 biolink:ChemicalSubstance 1,4-cineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_80788 chebi_ph7_3 GO:2000425 biolink:BiologicalProcess regulation of apoptotic cell clearance Any process that modulates the frequency, rate or extent of apoptotic cell clearance. go-plus.json regulation of programmed cell clearance|regulation of apoptotic cell removal|regulation of efferocytosis http://purl.obolibrary.org/obo/GO_2000425 GO:2000426 biolink:BiologicalProcess negative regulation of apoptotic cell clearance Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance. go-plus.json negative regulation of programmed cell clearance|negative regulation of efferocytosis|negative regulation of apoptotic cell removal http://purl.obolibrary.org/obo/GO_2000426 GO:2000427 biolink:BiologicalProcess positive regulation of apoptotic cell clearance Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance. go-plus.json positive regulation of apoptotic cell removal|positive regulation of programmed cell clearance|positive regulation of efferocytosis http://purl.obolibrary.org/obo/GO_2000427 CHEBI:111504 biolink:ChemicalSubstance validoxylamine A 7'-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_111504 chebi_ph7_3 GO:2000428 biolink:BiologicalProcess regulation of neutrophil aggregation Any process that modulates the frequency, rate or extent of neutrophil aggregation. go-plus.json regulation of neutrophilic leukocyte aggregation|regulation of neutrophil leucocyte aggregation|regulation of neutrocyte aggregation http://purl.obolibrary.org/obo/GO_2000428 CHEBI:111505 biolink:ChemicalSubstance validoxylamine A(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_111505 chebi_ph7_3 GO:2000429 biolink:BiologicalProcess negative regulation of neutrophil aggregation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation. go-plus.json negative regulation of neutrophil leucocyte aggregation|negative regulation of neutrocyte aggregation|negative regulation of neutrophilic leukocyte aggregation http://purl.obolibrary.org/obo/GO_2000429 CHEBI:65156 biolink:ChemicalSubstance Man-beta1-6-Ins-1-P-Cer(d18:0/24:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65156 chebi_ph7_3 CHEBI:111503 biolink:ChemicalSubstance validamine 7-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_111503 chebi_ph7_3 CHEBI:90118 biolink:ChemicalSubstance tricosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90118 chebi_ph7_3 GO:2000420 biolink:BiologicalProcess negative regulation of eosinophil extravasation Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000420 GO:2000421 biolink:BiologicalProcess positive regulation of eosinophil extravasation Any process that activates or increases the frequency, rate or extent of eosinophil extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000421 CHEBI:90119 biolink:ChemicalSubstance (2E)-tricosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90119 chebi_ph7_3 CHEBI:16137 biolink:ChemicalSubstance chondroitin D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16137 GO:2000422 biolink:BiologicalProcess regulation of eosinophil chemotaxis Any process that modulates the frequency, rate or extent of eosinophil chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000422 CHEBI:16138 biolink:ChemicalSubstance 2-deoxy-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16138 CHEBI:16135 biolink:ChemicalSubstance isobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16135 CHEBI:16136 biolink:ChemicalSubstance hydrogen sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16136 CHEBI:16133 biolink:ChemicalSubstance cyclopentanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16133 chebi_ph7_3 CHEBI:16134 biolink:ChemicalSubstance ammonia go-plus.json http://purl.obolibrary.org/obo/CHEBI_16134 CHEBI:16132 biolink:ChemicalSubstance 2-deoxy-D-ribose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16132 CHEBI:16130 biolink:ChemicalSubstance DDT go-plus.json http://purl.obolibrary.org/obo/CHEBI_16130 chebi_ph7_3 GO:2000434 biolink:BiologicalProcess regulation of protein neddylation Any process that modulates the frequency, rate or extent of protein neddylation. go-plus.json regulation of RUB1-protein conjugation http://purl.obolibrary.org/obo/GO_2000434 GO:2000435 biolink:BiologicalProcess negative regulation of protein neddylation Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation. go-plus.json negative regulation of RUB1-protein conjugation http://purl.obolibrary.org/obo/GO_2000435 GO:2000436 biolink:BiologicalProcess positive regulation of protein neddylation Any process that activates or increases the frequency, rate or extent of protein neddylation. go-plus.json positive regulation of RUB1-protein conjugation http://purl.obolibrary.org/obo/GO_2000436 GO:2000437 biolink:BiologicalProcess regulation of monocyte extravasation Any process that modulates the frequency, rate or extent of monocyte extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000437 GO:2000438 biolink:BiologicalProcess negative regulation of monocyte extravasation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000438 GO:2000439 biolink:BiologicalProcess positive regulation of monocyte extravasation Any process that activates or increases the frequency, rate or extent of monocyte extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000439 GO:2000430 biolink:BiologicalProcess positive regulation of neutrophil aggregation Any process that activates or increases the frequency, rate or extent of neutrophil aggregation. go-plus.json positive regulation of neutrophilic leukocyte aggregation|positive regulation of neutrophil leucocyte aggregation|positive regulation of neutrocyte aggregation http://purl.obolibrary.org/obo/GO_2000430 CHEBI:16128 biolink:ChemicalSubstance dTDP-4-dehydro-6-deoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16128 GO:2000431 biolink:BiologicalProcess regulation of cytokinesis, actomyosin contractile ring assembly Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly. go-plus.json regulation of contractile ring assembly http://purl.obolibrary.org/obo/GO_2000431 GO:2000432 biolink:BiologicalProcess negative regulation of cytokinesis, actomyosin contractile ring assembly Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly. go-plus.json negative regulation of contractile ring assembly http://purl.obolibrary.org/obo/GO_2000432 CHEBI:16126 biolink:ChemicalSubstance 3-(4-deoxy-beta-D-gluc-4-enosyluronic acid)-N-acetyl-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16126 CHEBI:90109 biolink:ChemicalSubstance L-3-sulfolactaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90109 chebi_ph7_3 GO:2000433 biolink:BiologicalProcess positive regulation of cytokinesis, actomyosin contractile ring assembly Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly. go-plus.json positive regulation of contractile ring assembly http://purl.obolibrary.org/obo/GO_2000433 CHEBI:16124 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_16124 chebi_ph7_3 CHEBI:16125 biolink:ChemicalSubstance hexadecan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16125 chebi_ph7_3 CHEBI:16122 biolink:ChemicalSubstance 3-(4-hydroxy-3,5-diiodophenyl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16122 CHEBI:90104 biolink:ChemicalSubstance D-3-sulfolactaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_90104 CHEBI:16123 biolink:ChemicalSubstance 6-oxocineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16123 chebi_ph7_3 CHEBI:16120 biolink:ChemicalSubstance 5-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16120 chebi_ph7_3 CHEBI:16121 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16121 CHEBI:16160 biolink:ChemicalSubstance O-succinyl-L-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16160 CHEBI:65172 biolink:ChemicalSubstance ximelagatran go-plus.json http://purl.obolibrary.org/obo/CHEBI_65172 chebi_ph7_3 CHEBI:16161 biolink:ChemicalSubstance CoA-disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16161 CHEBI:65173 biolink:ChemicalSubstance iloperidone go-plus.json http://purl.obolibrary.org/obo/CHEBI_65173 UBERON:0018321 biolink:AnatomicalEntity foramen for glossopharyngeal nerve Foramen that allows the passge of the glossopharyngeal nerve (cranial nerve IX). go-plus.json http://purl.obolibrary.org/obo/UBERON_0018321 GO:2000445 biolink:BiologicalProcess positive regulation of toll-like receptor 21 signaling pathway Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway. go-plus.json positive regulation of TLR21 signaling pathway|positive regulation of toll-like receptor 21 signalling pathway http://purl.obolibrary.org/obo/GO_2000445 GO:2000446 biolink:BiologicalProcess regulation of macrophage migration inhibitory factor signaling pathway Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. go-plus.json regulation of MIF signaling pathway|regulation of macrophage migration inhibitory factor signalling pathway http://purl.obolibrary.org/obo/GO_2000446 CHEBI:31755 biolink:ChemicalSubstance L-4-hydroxyphenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_31755 GO:2000447 biolink:BiologicalProcess negative regulation of macrophage migration inhibitory factor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. go-plus.json negative regulation of macrophage migration inhibitory factor signalling pathway|negative regulation of MIF signaling pathway http://purl.obolibrary.org/obo/GO_2000447 GO:2000448 biolink:BiologicalProcess positive regulation of macrophage migration inhibitory factor signaling pathway Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. go-plus.json positive regulation of macrophage migration inhibitory factor signalling pathway|positive regulation of MIF signaling pathway http://purl.obolibrary.org/obo/GO_2000448 GO:2000449 biolink:BiologicalProcess regulation of CD8-positive, alpha-beta T cell extravasation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000449 CHEBI:111522 biolink:ChemicalSubstance valienone 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_111522 chebi_ph7_3 CHEBI:111523 biolink:ChemicalSubstance validone 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_111523 chebi_ph7_3 GO:2000440 biolink:BiologicalProcess regulation of toll-like receptor 15 signaling pathway Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway. go-plus.json regulation of TLR15 signaling pathway|regulation of toll-like receptor 15 signalling pathway http://purl.obolibrary.org/obo/GO_2000440 GO:2000441 biolink:BiologicalProcess negative regulation of toll-like receptor 15 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway. go-plus.json negative regulation of toll-like receptor 15 signalling pathway|negative regulation of TLR15 signaling pathway http://purl.obolibrary.org/obo/GO_2000441 GO:2000442 biolink:BiologicalProcess positive regulation of toll-like receptor 15 signaling pathway Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway. go-plus.json positive regulation of toll-like receptor 15 signalling pathway|positive regulation of TLR15 signaling pathway http://purl.obolibrary.org/obo/GO_2000442 GO:2000443 biolink:BiologicalProcess regulation of toll-like receptor 21 signaling pathway Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway. go-plus.json regulation of TLR21 signaling pathway|regulation of toll-like receptor 21 signalling pathway http://purl.obolibrary.org/obo/GO_2000443 CHEBI:16159 biolink:ChemicalSubstance sulochrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16159 GO:2000444 biolink:BiologicalProcess negative regulation of toll-like receptor 21 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway. go-plus.json negative regulation of TLR21 signaling pathway|negative regulation of toll-like receptor 21 signalling pathway http://purl.obolibrary.org/obo/GO_2000444 CHEBI:111521 biolink:ChemicalSubstance valienone go-plus.json http://purl.obolibrary.org/obo/CHEBI_111521 chebi_ph7_3 CHEBI:16157 biolink:ChemicalSubstance D-arabinonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16157 chebi_ph7_3 CHEBI:16158 biolink:ChemicalSubstance steroid sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16158 CHEBI:16155 biolink:ChemicalSubstance myo-inositol 1,3,4,6-tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16155 CHEBI:16153 biolink:ChemicalSubstance N-acetyllactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16153 chebi_ph7_3 CHEBI:16154 biolink:ChemicalSubstance L-gulonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16154 CHEBI:16151 biolink:ChemicalSubstance 3,4-dihydrocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16151 chebi_ph7_3 CHEBI:16152 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16152 CHEBI:16150 biolink:ChemicalSubstance benzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16150 chebi_ph7_3 CHEBI:65180 biolink:ChemicalSubstance GDP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65180 GO:2000456 biolink:BiologicalProcess negative regulation of T-helper 17 cell extravasation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000456 CHEBI:111519 biolink:ChemicalSubstance 2,3-dichloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_111519 GO:2000457 biolink:BiologicalProcess positive regulation of T-helper 17 cell extravasation Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000457 GO:2000458 biolink:BiologicalProcess regulation of astrocyte chemotaxis Any process that modulates the frequency, rate or extent of astrocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000458 NCBITaxon:196117 biolink:OrganismalEntity Methanocaldococcaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_196117 GO:2000459 biolink:BiologicalProcess negative regulation of astrocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2000459 NCBITaxon:196118 biolink:OrganismalEntity Methanocaldococcus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_196118 CHEBI:111511 biolink:ChemicalSubstance (beta-D-glucopyranosyloxymethyl)deoxyuridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_111511 PR:000003112 biolink:Protein NFAT protein A protein that contains a Rel homology domain (RHD) (Pfam:PF00554) followed by an IPT/TIG domain (Pfam:PF01833). go-plus.json http://purl.obolibrary.org/obo/PR_000003112 PR:000003113 biolink:Protein nuclear factor of activated T-cells, cytoplasmic 1 An NFAT protein that is a translation product of the human NFATC1 gene or a 1:1 ortholog thereof. go-plus.json NF-ATc|NFATC1|NFATc1|NFATc|NF-ATc1|NFAT transcription complex cytosolic component|NFAT2 http://purl.obolibrary.org/obo/PR_000003113 GO:2000450 biolink:BiologicalProcess negative regulation of CD8-positive, alpha-beta T cell extravasation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000450 UBERON:0008998 biolink:AnatomicalEntity vasculature of brain System pertaining to blood vessels in the brain. go-plus.json cerebrovascular system|brain vasculature|intracerebral vasculature http://purl.obolibrary.org/obo/UBERON_0008998 GO:2000451 biolink:BiologicalProcess positive regulation of CD8-positive, alpha-beta T cell extravasation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000451 GO:2000452 biolink:BiologicalProcess regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000452 GO:2000453 biolink:BiologicalProcess negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000453 GO:2000454 biolink:BiologicalProcess positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000454 CHEBI:31763 biolink:ChemicalSubstance laricitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31763 CHEBI:16148 biolink:ChemicalSubstance heptadecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_16148 chebi_ph7_3 GO:2000455 biolink:BiologicalProcess regulation of T-helper 17 cell extravasation Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000455 CHEBI:16146 biolink:ChemicalSubstance maleamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16146 chebi_ph7_3 CHEBI:16147 biolink:ChemicalSubstance 11-O-demethyl-17-O-deacetylvindoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16147 CHEBI:16144 biolink:ChemicalSubstance selenophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16144 chebi_ph7_3 CHEBI:16145 biolink:ChemicalSubstance 3,5/4-trihydroxycyclohexane-1,2-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16145 CHEBI:16142 biolink:ChemicalSubstance 3-dehydro-L-gulonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16142 CHEBI:16143 biolink:ChemicalSubstance 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16143 UBERON:0008993 biolink:AnatomicalEntity habenular nucleus Either of the two neural nuclei within the habenula. go-plus.json nucleus habenulae|ganglion habenulae|habenular nuclei http://purl.obolibrary.org/obo/UBERON_0008993 CHEBI:16141 biolink:ChemicalSubstance undecaprenyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16141 UBERON:0008995 biolink:AnatomicalEntity nucleus of cerebellar nuclear complex Four accumulations of gray substance embedded in the white substance of the cerebellum, comprising the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii. go-plus.json cerebellar nucleus|deep cerebellar nucleus http://purl.obolibrary.org/obo/UBERON_0008995 GO:0016466 biolink:MolecularActivity obsolete hydrogen-translocating A-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae. go-plus.json hydrogen-translocating A-type ATPase activity|proton-translocating A-type ATPase activity http://purl.obolibrary.org/obo/GO_0016466 GO:0016467 biolink:MolecularActivity obsolete hydrogen-translocating F-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria. go-plus.json F1-ATPase activity|hydrogen-translocating F-type ATPase activity|ATP synthase|proton-translocating F-type ATPase activity http://purl.obolibrary.org/obo/GO_0016467 GO:0016468 biolink:MolecularActivity obsolete sodium-translocating F-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria. go-plus.json sodium-translocating F-type ATPase activity|ATP synthase http://purl.obolibrary.org/obo/GO_0016468 GO:0016469 biolink:CellularComponent proton-transporting two-sector ATPase complex A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. go-plus.json hydrogen-transporting two-sector ATPase complex|vacuolar hydrogen-transporting ATPase http://purl.obolibrary.org/obo/GO_0016469 goslim_pir|goslim_metagenomics UBERON:0008904 biolink:AnatomicalEntity neuromast Volcano-shaped lateral line sensory organ located in characteristic positions within the skin epithelium and containing hair cells and their support elements. go-plus.json neuromasts|lateral line organ|neuromast organ|lateral line neuromast http://purl.obolibrary.org/obo/UBERON_0008904 GO:0016462 biolink:MolecularActivity pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. Reactome:R-HSA-6810472 go-plus.json http://purl.obolibrary.org/obo/GO_0016462 GO:0016463 biolink:MolecularActivity P-type zinc transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out). MetaCyc:3.6.3.5-RXN|RHEA:20621|EC:7.2.2.12 go-plus.json ATP phosphohydrolase (Zn2+-exporting)|P(1B)-type ATPase activity|zinc-translocating P-type ATPase activity|Zn2+-exporting ATPase activity|zinc transmembrane transporter activity, phosphorylative mechanism|zinc exporting ATPase activity|P1B-type ATPase activity|zinc-exporting ATPase activity|Zn(2+)-exporting ATPase activity http://purl.obolibrary.org/obo/GO_0016463 GO:0016464 biolink:MolecularActivity chloroplast protein-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma. EC:7.4.2.4|MetaCyc:3.6.3.52-RXN go-plus.json AAA chloroplast protein-transporting ATPase|ATPase-coupled chloroplast protein transporter activity http://purl.obolibrary.org/obo/GO_0016464 GO:0016465 biolink:CellularComponent chaperonin ATPase complex Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts. go-plus.json http://purl.obolibrary.org/obo/GO_0016465 GO:0016460 biolink:CellularComponent myosin II complex A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures. go-plus.json conventional myosin http://purl.obolibrary.org/obo/GO_0016460 GO:0016461 biolink:CellularComponent unconventional myosin complex A portmanteau term for myosins other than myosin II. go-plus.json non-muscle myosin http://purl.obolibrary.org/obo/GO_0016461 GO:0016477 biolink:BiologicalProcess cell migration The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. Wikipedia:Cell_migration go-plus.json http://purl.obolibrary.org/obo/GO_0016477 GO:0016478 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016478 GO:0016479 biolink:BiologicalProcess negative regulation of transcription by RNA polymerase I Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I. go-plus.json negative regulation of transcription from Pol I promoter|negative regulation of transcription from RNA polymerase I promoter|down-regulation of transcription from RNA polymerase I promoter|downregulation of transcription from RNA polymerase I promoter|down regulation of transcription from RNA polymerase I promoter|inhibition of transcription from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0016479 GO:0016473 biolink:CellularComponent sodium ion-transporting F-type ATPase complex A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism. go-plus.json sodium-translocating F-type ATPase complex http://purl.obolibrary.org/obo/GO_0016473 GO:0016474 biolink:CellularComponent sodium ion-transporting V-type ATPase complex A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. go-plus.json sodium-translocating V-type ATPase complex http://purl.obolibrary.org/obo/GO_0016474 GO:0016475 biolink:BiologicalProcess detection of nuclear:cytoplasmic ratio The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell. go-plus.json interpretation of nuclear:cytoplasmic ratio|sensing of nuclear:cytoplasmic ratio http://purl.obolibrary.org/obo/GO_0016475 GO:0016476 biolink:BiologicalProcess regulation of embryonic cell shape Any process that modulates the surface configuration of an embryonic cell. go-plus.json shape changes of embryonic cells http://purl.obolibrary.org/obo/GO_0016476 GO:0016470 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016470 GO:0016471 biolink:CellularComponent vacuolar proton-transporting V-type ATPase complex A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen. go-plus.json vacuolar hydrogen-translocating V-type ATPase complex http://purl.obolibrary.org/obo/GO_0016471 GO:0016472 biolink:CellularComponent sodium ion-transporting two-sector ATPase complex A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis. go-plus.json sodium-transporting two-sector ATPase complex http://purl.obolibrary.org/obo/GO_0016472 goslim_pir NCBITaxon:338152 biolink:OrganismalEntity Felinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_338152 GO:0090381 biolink:BiologicalProcess regulation of heart induction Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0090381 GO:0090382 biolink:BiologicalProcess phagosome maturation A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0090382 GO:0090380 biolink:BiologicalProcess seed trichome maturation A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0090380 GO:0016448 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016448 GO:0016449 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016449 GO:0016444 biolink:BiologicalProcess somatic cell DNA recombination Recombination occurring within or between DNA molecules in somatic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0016444 GO:0016445 biolink:BiologicalProcess somatic diversification of immunoglobulins The somatic process that results in the generation of sequence diversity of immunoglobulins. go-plus.json somatic diversification of antibodies http://purl.obolibrary.org/obo/GO_0016445 GO:0016446 biolink:BiologicalProcess somatic hypermutation of immunoglobulin genes Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins. go-plus.json somatic hypermutation of antibody genes http://purl.obolibrary.org/obo/GO_0016446 GO:0016447 biolink:BiologicalProcess somatic recombination of immunoglobulin gene segments The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus. go-plus.json somatic recombination of antibody gene segments http://purl.obolibrary.org/obo/GO_0016447 GO:0090385 biolink:BiologicalProcess phagosome-lysosome fusion The creation of a phagolysosome from a phagosome and a lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0090385 GO:0016440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016440 GO:0090386 biolink:BiologicalProcess phagosome maturation involved in apoptotic cell clearance A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0090386 GO:0016441 biolink:BiologicalProcess posttranscriptional gene silencing The inactivation of gene expression by a posttranscriptional mechanism. Wikipedia:Post_transcriptional_gene_silencing go-plus.json post-transcriptional gene silencing|PTGS|cosuppression|quelling http://purl.obolibrary.org/obo/GO_0016441 GO:0090383 biolink:BiologicalProcess phagosome acidification Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion. go-plus.json phagosomal acidification http://purl.obolibrary.org/obo/GO_0090383 GO:0016442 biolink:CellularComponent RISC complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. Wikipedia:RNA-induced_silencing_complex go-plus.json RNA-induced silencing complex|micro-ribonucleoprotein complex|miRNP complex http://purl.obolibrary.org/obo/GO_0016442 GO:0016443 biolink:MolecularActivity bidentate ribonuclease III activity Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference. EC:3.1.26.- go-plus.json bidentate RNase III activity http://purl.obolibrary.org/obo/GO_0016443 GO:0090384 biolink:BiologicalProcess phagosome-lysosome docking The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere. go-plus.json lysosome recruitment to phagosome http://purl.obolibrary.org/obo/GO_0090384 GO:0090389 biolink:BiologicalProcess phagosome-lysosome fusion involved in apoptotic cell clearance The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance. go-plus.json http://purl.obolibrary.org/obo/GO_0090389 GO:0090387 biolink:BiologicalProcess phagolysosome assembly involved in apoptotic cell clearance The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance. go-plus.json http://purl.obolibrary.org/obo/GO_0090387 GO:0090388 biolink:BiologicalProcess phagosome-lysosome docking involved in apoptotic cell clearance The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere. go-plus.json http://purl.obolibrary.org/obo/GO_0090388 GO:0090392 biolink:BiologicalProcess sepal giant cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C. go-plus.json http://purl.obolibrary.org/obo/GO_0090392 GO:0090393 biolink:BiologicalProcess sepal giant cell development The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json sepal giant cell formation http://purl.obolibrary.org/obo/GO_0090393 GO:0090390 biolink:BiologicalProcess phagosome acidification involved in apoptotic cell clearance Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance. go-plus.json http://purl.obolibrary.org/obo/GO_0090390 GO:0090391 biolink:BiologicalProcess granum assembly A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts. go-plus.json grana formation http://purl.obolibrary.org/obo/GO_0090391 GO:0016459 biolink:CellularComponent myosin complex A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes. go-plus.json http://purl.obolibrary.org/obo/GO_0016459 GO:0016455 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016455 GO:0016456 biolink:CellularComponent X chromosome located dosage compensation complex, transcription activating An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster. go-plus.json dosage compensation complex http://purl.obolibrary.org/obo/GO_0016456 GO:0016457 biolink:BiologicalProcess dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster. go-plus.json dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome http://purl.obolibrary.org/obo/GO_0016457 GO:0016458 biolink:BiologicalProcess gene silencing Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression. Wikipedia:Gene_silencing go-plus.json http://purl.obolibrary.org/obo/GO_0016458 goslim_pir|goslim_drosophila GO:0016451 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016451 GO:0090396 biolink:CellularComponent leaf papilla A plant cell papilla that is part of a leaf papilla cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090396 GO:0016452 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016452 GO:0090397 biolink:CellularComponent stigma papilla A plant cell papilla that is part of a stigma papilla cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090397 GO:0090394 biolink:BiologicalProcess negative regulation of excitatory postsynaptic potential Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. go-plus.json reduction of excitatory postsynaptic membrane potential|negative regulation of excitatory post-synaptic membrane potential|negative regulation of EPSP http://purl.obolibrary.org/obo/GO_0090394 GO:0016453 biolink:MolecularActivity C-acetyltransferase activity Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016453 GO:0090395 biolink:CellularComponent plant cell papilla A cell projection that is a short, rounded projection from a plant epidermal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090395 GO:0016454 biolink:MolecularActivity C-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016454 GO:0090398 biolink:BiologicalProcess cellular senescence A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest. go-plus.json http://purl.obolibrary.org/obo/GO_0090398 GO:0016450 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016450 GO:0090399 biolink:BiologicalProcess replicative senescence A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging. go-plus.json http://purl.obolibrary.org/obo/GO_0090399 CHEBI:41183 biolink:ChemicalSubstance D-erythro-biopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_41183 chebi_ph7_3 CHEBI:41189 biolink:ChemicalSubstance butane-1,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_41189 chebi_ph7_3 GO:0016426 biolink:MolecularActivity tRNA (adenine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine. go-plus.json http://purl.obolibrary.org/obo/GO_0016426 GO:0016427 biolink:MolecularActivity tRNA (cytosine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0016427 GO:0016428 biolink:MolecularActivity tRNA (cytosine-5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine. Reactome:R-HSA-6785438|Reactome:R-HSA-6782388|Reactome:R-HSA-6785409|Reactome:R-HSA-6782419|Reactome:R-HSA-8932765 go-plus.json transfer ribonucleate cytosine 5-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity|transfer RNA cytosine 5-methyltransferase activity http://purl.obolibrary.org/obo/GO_0016428 GO:0016429 biolink:MolecularActivity tRNA (adenine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine. Reactome:R-HSA-6783492|Reactome:R-HSA-6787525|Reactome:R-HSA-6787594 go-plus.json transfer RNA (adenine-1) methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity|transfer ribonucleate adenine 1-methyltransferase activity|adenine-1-methylase activity|1-methyladenine transfer RNA methyltransferase activity http://purl.obolibrary.org/obo/GO_0016429 GO:0016422 biolink:MolecularActivity mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am. RHEA:22744|EC:2.1.1.62|MetaCyc:2.1.1.62-RXN go-plus.json S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity|messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity|S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0016422 UBERON:0008946 biolink:AnatomicalEntity lung parenchyma A parenchyma that is part of a lung. go-plus.json parenchyma of lung|respiratory portion of lung|pulmonary parenchyma http://purl.obolibrary.org/obo/UBERON_0008946 GO:0016423 biolink:MolecularActivity tRNA (guanine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine. go-plus.json tRNA (guanosine) methyltransferase activity http://purl.obolibrary.org/obo/GO_0016423 UBERON:0008947 biolink:AnatomicalEntity respiratory primordium go-plus.json http://purl.obolibrary.org/obo/UBERON_0008947 GO:0016424 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016424 GO:0016425 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016425 GO:0016420 biolink:MolecularActivity malonyltransferase activity Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016420 GO:0016421 biolink:MolecularActivity CoA carboxylase activity Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0016421 GO:0016437 biolink:MolecularActivity tRNA cytidylyltransferase activity Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1). EC:2.7.7.72|MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN go-plus.json ATP(CTP)-tRNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase|transfer ribonucleic acid nucleotidyl transferase|transfer ribonucleic adenylyl (cytidylyl) transferase|CTP:tRNA cytidylyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|-C-C-A pyrophosphorylase|transfer ribonucleate adenylyltransferase|CTP(ATP):tRNA nucleotidyltransferase|transfer ribonucleate nucleotidyltransferase|transfer RNA adenylyltransferase|ATP(CTP):tRNA nucleotidyltransferase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|ATP (CTP):tRNA nucleotidyltransferase|transfer ribonucleate cytidylyltransferase|ribonucleic cytidylyltransferase|transfer-RNA nucleotidyltransferase|tRNA CCA-pyrophosphorylase activity|tRNA CCA-diphosphorylase activity http://purl.obolibrary.org/obo/GO_0016437 GO:0016438 biolink:MolecularActivity tRNA-queuosine beta-mannosyltransferase activity Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine. RHEA:12885|MetaCyc:2.4.1.110-RXN|EC:2.4.1.110 go-plus.json GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0016438 GO:0016439 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016439 GO:0016433 biolink:MolecularActivity rRNA (adenine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine. go-plus.json http://purl.obolibrary.org/obo/GO_0016433 GO:0016434 biolink:MolecularActivity rRNA (cytosine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0016434 GO:0016435 biolink:MolecularActivity rRNA (guanine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine. go-plus.json http://purl.obolibrary.org/obo/GO_0016435 GO:0016436 biolink:MolecularActivity rRNA (uridine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine. go-plus.json http://purl.obolibrary.org/obo/GO_0016436 GO:0016430 biolink:MolecularActivity tRNA (adenine-N6-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine. RHEA:16785|MetaCyc:TRNA-ADENINE-N6--METHYLTRANSFERASE-RXN|EC:2.1.1.55 go-plus.json S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0016430 GO:0016431 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016431 GO:0016432 biolink:MolecularActivity tRNA-uridine aminocarboxypropyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine. MetaCyc:2.5.1.25-RXN|EC:2.5.1.25|RHEA:12300 go-plus.json S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity http://purl.obolibrary.org/obo/GO_0016432 NCBITaxon:338191 biolink:OrganismalEntity Nitrosopumilus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_338191 NCBITaxon:338192 biolink:OrganismalEntity Nitrosopumilus maritimus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_338192 NCBITaxon:338190 biolink:OrganismalEntity Nitrosopumilaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_338190 GO:0016408 biolink:MolecularActivity C-acyltransferase activity Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016408 GO:0016409 biolink:MolecularActivity palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. Reactome:R-HSA-203567|Reactome:R-HSA-5686304 go-plus.json http://purl.obolibrary.org/obo/GO_0016409 GO:0016404 biolink:MolecularActivity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+. MetaCyc:1.1.1.141-RXN|Reactome:R-HSA-2161662|Reactome:R-HSA-9024766|EC:1.1.1.141|Reactome:R-HSA-9023968|RHEA:11876|Reactome:R-HSA-2161779 go-plus.json (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity|15-hydroxyprostanoic dehydrogenase activity|15-OH-PGDH|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)|15-hydroxyprostaglandin dehydrogenase activity|11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity|prostaglandin dehydrogenase activity|NAD-specific 15-hydroxyprostaglandin dehydrogenase activity http://purl.obolibrary.org/obo/GO_0016404 GO:0016405 biolink:MolecularActivity CoA-ligase activity Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA. Reactome:R-HSA-159567|Reactome:R-HSA-159443|Reactome:R-HSA-6798345|Reactome:R-HSA-177157 go-plus.json http://purl.obolibrary.org/obo/GO_0016405 GO:0016406 biolink:MolecularActivity carnitine O-acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016406 GO:0016407 biolink:MolecularActivity acetyltransferase activity Catalysis of the transfer of an acetyl group to an acceptor molecule. Reactome:R-HSA-5682044|Reactome:R-HSA-6805638|Reactome:R-HSA-5628871|Reactome:R-HSA-5660660|Reactome:R-HSA-73736|Reactome:R-HSA-6792712 go-plus.json acetylase activity http://purl.obolibrary.org/obo/GO_0016407 GO:0016400 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016400 GO:0016401 biolink:MolecularActivity palmitoyl-CoA oxidase activity Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide. EC:1.3.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016401 GO:0016402 biolink:MolecularActivity pristanoyl-CoA oxidase activity Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide. Reactome:R-HSA-389891|RHEA:40459|Reactome:R-HSA-389889 go-plus.json http://purl.obolibrary.org/obo/GO_0016402 GO:0016403 biolink:MolecularActivity dimethylargininase activity Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline. EC:3.5.3.18|RHEA:17305|Reactome:R-HSA-5693373|MetaCyc:DIMETHYLARGININASE-RXN go-plus.json NG,NG-dimethylarginine dimethylaminohydrolase activity|N(G),N(G)-dimethylarginine dimethylaminohydrolase activity|dimethylarginine dimethylaminohydrolase activity|NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity http://purl.obolibrary.org/obo/GO_0016403 CHEBI:65102 biolink:ChemicalSubstance 3-hydroxy fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65102 chebi_ph7_3 UBERON:0008906 biolink:AnatomicalEntity lateral line nerve Cranial nerves that carry afferent and efferent fibers for the lateral line system. go-plus.json lateral line nerves http://purl.obolibrary.org/obo/UBERON_0008906 UBERON:0008907 biolink:AnatomicalEntity dermal bone Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. go-plus.json dermal bones http://purl.obolibrary.org/obo/UBERON_0008907 GO:0016419 biolink:MolecularActivity S-malonyltransferase activity Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule. EC:2.3.1.39 go-plus.json http://purl.obolibrary.org/obo/GO_0016419 UBERON:0008909 biolink:AnatomicalEntity perichordal bone Bone element that is adjacent to the notochord. go-plus.json perichordal bones|perichordal bone http://purl.obolibrary.org/obo/UBERON_0008909 CHEBI:546807 biolink:ChemicalSubstance beta-D-Galp-(1->3)-D-GalpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_546807 chebi_ph7_3 CHEBI:546808 biolink:ChemicalSubstance alpha-D-Gal-(1->4)-D-Gal go-plus.json http://purl.obolibrary.org/obo/CHEBI_546808 chebi_ph7_3 CHEBI:65100 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_65100 CHEBI:65101 biolink:ChemicalSubstance 2-hydroxyhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65101 GO:0016415 biolink:MolecularActivity octanoyltransferase activity Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule. EC:2.3.1.181 go-plus.json http://purl.obolibrary.org/obo/GO_0016415 GO:0016416 biolink:MolecularActivity O-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule. Reactome:R-HSA-2404137|Reactome:R-HSA-2453855|Reactome:R-HSA-2466710 go-plus.json http://purl.obolibrary.org/obo/GO_0016416 GO:0016417 biolink:MolecularActivity S-acyltransferase activity Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016417 GO:0016418 biolink:MolecularActivity S-acetyltransferase activity Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule. EC:2.3.1.38 go-plus.json http://purl.obolibrary.org/obo/GO_0016418 GO:0016411 biolink:MolecularActivity acylglycerol O-acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule. Reactome:R-HSA-1482654|Reactome:R-HSA-1482647 go-plus.json http://purl.obolibrary.org/obo/GO_0016411 CHEBI:65106 biolink:ChemicalSubstance 1-monolysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_65106 GO:0016412 biolink:MolecularActivity serine O-acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule. EC:2.3.1.30 go-plus.json http://purl.obolibrary.org/obo/GO_0016412 UBERON:0008913 biolink:AnatomicalEntity perichondral bone Bone element that is located on the surface of a cartilage element. go-plus.json perichondral bones|perichondral bone http://purl.obolibrary.org/obo/UBERON_0008913 CHEBI:65107 biolink:ChemicalSubstance N-hexadecanoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65107 chebi_ph7_3 GO:0016413 biolink:MolecularActivity O-acetyltransferase activity Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016413 CHEBI:65108 biolink:ChemicalSubstance gamma-L-glutamylbutirosin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_65108 GO:0016414 biolink:MolecularActivity O-octanoyltransferase activity Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016414 CHEBI:65109 biolink:ChemicalSubstance butirosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_65109 GO:0016410 biolink:MolecularActivity N-acyltransferase activity Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. Reactome:R-HSA-177160 go-plus.json http://purl.obolibrary.org/obo/GO_0016410 GO:1905370 biolink:CellularComponent serine-type endopeptidase complex A protein complex which is capable of serine-type endopeptidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905370 GO:1905371 biolink:BiologicalProcess ceramide phosphoethanolamine metabolic process The chemical reactions and pathways involving ceramide phosphoethanolamine. go-plus.json ceramide phosphoethanolamine metabolism http://purl.obolibrary.org/obo/GO_1905371 GO:1905372 biolink:BiologicalProcess ceramide phosphoethanolamine catabolic process The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine. go-plus.json ceramide phosphoethanolamine degradation|ceramide phosphoethanolamine breakdown|ceramide phosphoethanolamine catabolism http://purl.obolibrary.org/obo/GO_1905372 GO:1905373 biolink:BiologicalProcess ceramide phosphoethanolamine biosynthetic process The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine. go-plus.json ceramide phosphoethanolamine anabolism|ceramide phosphoethanolamine biosynthesis|ceramide phosphoethanolamine synthesis|ceramide phosphoethanolamine formation http://purl.obolibrary.org/obo/GO_1905373 GO:1905374 biolink:BiologicalProcess response to homocysteine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus. go-plus.json response to Hcy|response to 2-amino-4-mercaptobutyric acid|response to 2-amino-4-sulfanylbutanoic acid http://purl.obolibrary.org/obo/GO_1905374 GO:1905375 biolink:BiologicalProcess cellular response to homocysteine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus. go-plus.json cellular response to 2-amino-4-sulfanylbutanoic acid|cellular response to Hcy|cellular response to 2-amino-4-mercaptobutyric acid http://purl.obolibrary.org/obo/GO_1905375 GO:1905376 biolink:BiologicalProcess negative regulation of cytochrome-c oxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity. go-plus.json negative regulation of cbb3-type cytochrome c oxidase|down-regulation of caa3-type cytochrome c oxidase|down-regulation of cbb3-type cytochrome c oxidase|negative regulation of caa3-type cytochrome c oxidase|down-regulation of NADH cytochrome c oxidase|inhibition of ferrocytochrome c oxidase|negative regulation of NADH cytochrome c oxidase|inhibition of cytochrome oxidase activity|inhibition of warburg's respiratory enzyme activity|down regulation of cytochrome aa3 activity|inhibition of ferrocytochrome-c:oxygen oxidoreductase|inhibition of ba3-type cytochrome c oxidase|negative regulation of complex IV (mitochondrial electron transport) activity|inhibition of aa3-type cytochrome c oxidase|down-regulation of complex IV (mitochondrial electron transport) activity|downregulation of cytochrome a3 activity|down regulation of cytochrome c oxidase activity|downregulation of cytochrome aa3 activity|down-regulation of cytochrome-c oxidase activity|inhibition of NADH cytochrome c oxidase|down regulation of ferrocytochrome c oxidase|negative regulation of indophenol oxidase|downregulation of caa3-type cytochrome c oxidase|down-regulation of indophenol oxidase|inhibition of indophenolase|downregulation of cbb3-type cytochrome c oxidase|down regulation of warburg's respiratory enzyme activity|down regulation of cytochrome oxidase activity|down regulation of ba3-type cytochrome c oxidase|down regulation of cytochrome a3 activity|down regulation of ferrocytochrome-c:oxygen oxidoreductase|downregulation of cytochrome c oxidase activity|downregulation of ferrocytochrome c oxidase|down regulation of aa3-type cytochrome c oxidase|down regulation of caa3-type cytochrome c oxidase|down regulation of cbb3-type cytochrome c oxidase|downregulation of warburg's respiratory enzyme activity|downregulation of complex IV (mitochondrial electron transport) activity|downregulation of cytochrome oxidase activity|downregulation of ferrocytochrome-c:oxygen oxidoreductase|inhibition of cytochrome-c oxidase activity|downregulation of ba3-type cytochrome c oxidase|downregulation of aa3-type cytochrome c oxidase|down regulation of indophenolase|down-regulation of cytochrome aa3 activity|negative regulation of cytochrome aa3 activity|down regulation of complex IV (mitochondrial electron transport) activity|inhibition of cytochrome a3 activity|downregulation of indophenol oxidase|inhibition of cbb3-type cytochrome c oxidase|downregulation of indophenolase|down regulation of NADH cytochrome c oxidase|inhibition of caa3-type cytochrome c oxidase|negative regulation of ferrocytochrome c oxidase|negative regulation of cytochrome c oxidase activity|down-regulation of cytochrome c oxidase activity|down-regulation of ferrocytochrome c oxidase|down regulation of indophenol oxidase|down-regulation of cytochrome oxidase activity|down-regulation of warburg's respiratory enzyme activity|negative regulation of cytochrome oxidase activity|negative regulation of warburg's respiratory enzyme activity|down-regulation of ba3-type cytochrome c oxidase|downregulation of NADH cytochrome c oxidase|down-regulation of ferrocytochrome-c:oxygen oxidoreductase|negative regulation of ba3-type cytochrome c oxidase|negative regulation of ferrocytochrome-c:oxygen oxidoreductase|down-regulation of aa3-type cytochrome c oxidase|negative regulation of aa3-type cytochrome c oxidase|inhibition of complex IV (mitochondrial electron transport) activity|down regulation of cytochrome-c oxidase activity|inhibition of cytochrome c oxidase activity|negative regulation of indophenolase|inhibition of cytochrome aa3 activity|inhibition of indophenol oxidase|down-regulation of indophenolase|down-regulation of cytochrome a3 activity|negative regulation of cytochrome a3 activity|downregulation of cytochrome-c oxidase activity http://purl.obolibrary.org/obo/GO_1905376 GO:1905377 biolink:BiologicalProcess response to D-galactose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus. go-plus.json response to D-galacto-hexose|response to D-Gal http://purl.obolibrary.org/obo/GO_1905377 GO:1905367 biolink:BiologicalProcess positive regulation of intralumenal vesicle formation Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation. go-plus.json up regulation of intralumenal vesicle formation|up-regulation of endosome membrane budding|upregulation of intralumenal vesicle formation|upregulation of endosome membrane budding|activation of intralumenal vesicle formation|up-regulation of intralumenal vesicle formation|up regulation of endosome membrane budding|activation of endosome membrane budding|positive regulation of endosome membrane budding http://purl.obolibrary.org/obo/GO_1905367 GO:0090569 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090569 GO:1905368 biolink:CellularComponent peptidase complex A protein complex which is capable of peptidase activity. go-plus.json tryptase complex|protease complex http://purl.obolibrary.org/obo/GO_1905368 GO:0090567 biolink:BiologicalProcess reproductive shoot system development The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0090567 GO:1905369 biolink:CellularComponent endopeptidase complex A protein complex which is capable of endopeptidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905369 GO:0090568 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090568 GO:0090561 biolink:BiologicalProcess nuclear migration during mitotic telophase The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090561 GO:0090562 biolink:MolecularActivity protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090562 GO:0090560 biolink:MolecularActivity 2-(3-amino-3-carboxypropyl)histidine synthase activity Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2]. RHEA:36783|Reactome:R-HSA-5358494|MetaCyc:RXN-11371 go-plus.json http://purl.obolibrary.org/obo/GO_0090560 GO:0090565 biolink:MolecularActivity protein-phosphocysteine-mannitol phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json http://purl.obolibrary.org/obo/GO_0090565 GO:0090566 biolink:MolecularActivity protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090566 GO:0090563 biolink:MolecularActivity protein-phosphocysteine-sugar phosphotransferase activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json http://purl.obolibrary.org/obo/GO_0090563 GO:0090564 biolink:MolecularActivity protein-phosphocysteine-glucose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json http://purl.obolibrary.org/obo/GO_0090564 GO:1905380 biolink:BiologicalProcess regulation of snRNA transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II. go-plus.json regulation of snRNA transcription from RNA polymerase II promoter|regulation of snRNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_1905380 GO:1905381 biolink:BiologicalProcess negative regulation of snRNA transcription by RNA polymerase II Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II. go-plus.json negative regulation of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from RNA polymerase II promoter|negative regulation of snRNA transcription from Pol II promoter|down-regulation of snRNA transcription from Pol II promoter|down-regulation of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_1905381 GO:1905382 biolink:BiologicalProcess positive regulation of snRNA transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II. go-plus.json upregulation of snRNA transcription from RNA polymerase II promoter|activation of snRNA transcription from Pol II promoter|up-regulation of snRNA transcription from Pol II promoter|up regulation of snRNA transcription from RNA polymerase II promoter|activation of snRNA transcription from RNA polymerase II promoter|positive regulation of snRNA transcription from Pol II promoter|up regulation of snRNA transcription from Pol II promoter|up-regulation of snRNA transcription from RNA polymerase II promoter|upregulation of snRNA transcription from Pol II promoter|positive regulation of snRNA transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1905382 GO:1905383 biolink:BiologicalProcess protein localization to presynapse A process in which a protein is transported to, or maintained in, a location within a presynapse. go-plus.json protein localisation to presynapse|recruitment of presynaptic proteins|protein localisation in presynapse|protein localization in presynapse http://purl.obolibrary.org/obo/GO_1905383 GO:1905384 biolink:BiologicalProcess regulation of protein localization to presynapse Any process that modulates the frequency, rate or extent of protein localization to presynapse. go-plus.json regulation of protein localisation in presynapse|regulation of protein localization in presynapse|regulation of recruitment of presynaptic proteins|regulation of protein localisation to presynapse http://purl.obolibrary.org/obo/GO_1905384 GO:1905385 biolink:BiologicalProcess negative regulation of protein localization to presynapse Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse. go-plus.json inhibition of protein localisation to presynapse|downregulation of protein localization to presynapse|inhibition of recruitment of presynaptic proteins|down-regulation of protein localization in presynapse|negative regulation of protein localization in presynapse|downregulation of protein localisation in presynapse|down regulation of protein localization to presynapse|inhibition of protein localization to presynapse|down regulation of protein localisation in presynapse|inhibition of protein localisation in presynapse|downregulation of protein localization in presynapse|down regulation of recruitment of presynaptic proteins|down regulation of protein localization in presynapse|down-regulation of protein localisation to presynapse|downregulation of recruitment of presynaptic proteins|negative regulation of protein localisation to presynapse|inhibition of protein localization in presynapse|down-regulation of protein localization to presynapse|negative regulation of recruitment of presynaptic proteins|down-regulation of recruitment of presynaptic proteins|downregulation of protein localisation to presynapse|negative regulation of protein localisation in presynapse|down-regulation of protein localisation in presynapse|down regulation of protein localisation to presynapse http://purl.obolibrary.org/obo/GO_1905385 GO:1905386 biolink:BiologicalProcess positive regulation of protein localization to presynapse Any process that activates or increases the frequency, rate or extent of protein localization to presynapse. go-plus.json up regulation of protein localisation in presynapse|up-regulation of recruitment of presynaptic proteins|upregulation of protein localisation to presynapse|positive regulation of protein localization in presynapse|up regulation of protein localization in presynapse|upregulation of protein localization to presynapse|upregulation of recruitment of presynaptic proteins|up-regulation of protein localisation to presynapse|upregulation of protein localisation in presynapse|activation of protein localisation to presynapse|up-regulation of protein localization to presynapse|upregulation of protein localization in presynapse|activation of protein localization to presynapse|up regulation of recruitment of presynaptic proteins|up-regulation of protein localisation in presynapse|activation of protein localisation in presynapse|positive regulation of protein localisation to presynapse|activation of recruitment of presynaptic proteins|positive regulation of recruitment of presynaptic proteins|up regulation of protein localisation to presynapse|up-regulation of protein localization in presynapse|activation of protein localization in presynapse|up regulation of protein localization to presynapse|positive regulation of protein localisation in presynapse http://purl.obolibrary.org/obo/GO_1905386 GO:1905387 biolink:BiologicalProcess response to beta-carotene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus. go-plus.json response to beta,beta-carotene http://purl.obolibrary.org/obo/GO_1905387 GO:1905388 biolink:BiologicalProcess cellular response to beta-carotene Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus. go-plus.json cellular response to beta,beta-carotene http://purl.obolibrary.org/obo/GO_1905388 GO:1905378 biolink:BiologicalProcess cellular response to D-galactose Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus. go-plus.json cellular response to D-Gal|cellular response to D-galacto-hexose http://purl.obolibrary.org/obo/GO_1905378 GO:1905379 biolink:CellularComponent beta-N-acetylhexosaminidase complex A protein complex which is capable of beta-N-acetylhexosaminidase activity. go-plus.json HEX B complex|HEX A complex|HEX S complex http://purl.obolibrary.org/obo/GO_1905379 GO:0090578 biolink:CellularComponent RNA polymerase V transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V. go-plus.json RNA polymerase V transcription factor complex http://purl.obolibrary.org/obo/GO_0090578 GO:0090579 biolink:BiologicalProcess obsolete dsDNA loop formation OBSOLETE. The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule. go-plus.json dsDNA looping|chromatin looping http://purl.obolibrary.org/obo/GO_0090579 GO:0090572 biolink:CellularComponent RNA polymerase III transcription repressor complex A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0090572 GO:0090573 biolink:CellularComponent RNA polymerase IV transcription repressor complex A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0090573 GO:0090570 biolink:CellularComponent RNA polymerase I transcription repressor complex A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0090570 GO:0090571 biolink:CellularComponent RNA polymerase II transcription repressor complex A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0090571 GO:0090576 biolink:CellularComponent RNA polymerase III transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III. go-plus.json RNA polymerase III transcription factor complex http://purl.obolibrary.org/obo/GO_0090576 GO:0090577 biolink:CellularComponent RNA polymerase IV transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV. go-plus.json RNA polymerase IV transcription factor complex http://purl.obolibrary.org/obo/GO_0090577 GO:0090574 biolink:CellularComponent RNA polymerase V transcription repressor complex A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0090574 GO:0090575 biolink:CellularComponent RNA polymerase II transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II. go-plus.json RNA polymerase II transcription factor complex http://purl.obolibrary.org/obo/GO_0090575 GO:1905390 biolink:BiologicalProcess cellular response to leukotriene B4 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus. go-plus.json cellular response to LTB4 http://purl.obolibrary.org/obo/GO_1905390 GO:1905391 biolink:BiologicalProcess regulation of protein localization to cell division site involved in cell separation after cytokinesis Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis. go-plus.json regulation of protein localisation to cell division site involved in cell separation following cytokinesis|regulation of protein localisation to cell division site involved in cytokinetic cell separation|regulation of protein localisation to cell division site involved in mitotic cytokinetic cell separation|regulation of protein localisation to cell division site involved in cell separation after cytokinesis http://purl.obolibrary.org/obo/GO_1905391 GO:1905392 biolink:BiologicalProcess plant organ morphogenesis The developmental process by which a plant organ is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_1905392 GO:1905393 biolink:BiologicalProcess plant organ formation The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_1905393 GO:1905394 biolink:MolecularActivity retromer complex binding Binding to a retromer complex. go-plus.json http://purl.obolibrary.org/obo/GO_1905394 GO:1905395 biolink:BiologicalProcess response to flavonoid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905395 GO:1905396 biolink:BiologicalProcess cellular response to flavonoid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905396 GO:1905397 biolink:BiologicalProcess activated CD8-positive, alpha-beta T cell apoptotic process Any apoptotic process in an activated CD8-positive, alpha-beta T cell. go-plus.json activated CD8-positive, alpha-beta T-cell apoptosis|activated CD8-positive, alpha-beta T-lymphocyte apoptosis|activated CD8-positive, alpha-beta T-cell apoptotic process|activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activated CD8-positive, alpha-beta T cell apoptosis|activated CD8-positive, alpha-beta T lymphocyte apoptosis|activated CD8-positive, alpha-beta T lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_1905397 GO:1905398 biolink:BiologicalProcess activated CD4-positive, alpha-beta T cell apoptotic process Any apoptotic process in an activated CD4-positive, alpha-beta T cell. go-plus.json activated CD4-positive, alpha-beta T-cell apoptosis|activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activated CD4-positive, alpha-beta T-cell apoptotic process|activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activated CD4-positive, alpha-beta T cell apoptosis|activated CD4-positive, alpha-beta T lymphocyte apoptosis|activated CD4-positive, alpha-beta T lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_1905398 GO:1905399 biolink:BiologicalProcess regulation of activated CD4-positive, alpha-beta T cell apoptotic process Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. go-plus.json regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|regulation of activated CD4-positive, alpha-beta T cell apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|regulation of activated CD4-positive, alpha-beta T-cell apoptosis http://purl.obolibrary.org/obo/GO_1905399 GO:0090547 biolink:BiologicalProcess response to low humidity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere. go-plus.json http://purl.obolibrary.org/obo/GO_0090547 GO:1905389 biolink:BiologicalProcess response to leukotriene B4 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus. go-plus.json response to LTB4 http://purl.obolibrary.org/obo/GO_1905389 GO:0090548 biolink:BiologicalProcess response to nitrate starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate. go-plus.json http://purl.obolibrary.org/obo/GO_0090548 GO:0090545 biolink:CellularComponent CHD-type complex A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure. go-plus.json http://purl.obolibrary.org/obo/GO_0090545 GO:0090546 biolink:BiologicalProcess chlorophyll fluorescence The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light. go-plus.json http://purl.obolibrary.org/obo/GO_0090546 GO:0090549 biolink:BiologicalProcess response to carbon starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source. go-plus.json http://purl.obolibrary.org/obo/GO_0090549 GO:0090540 biolink:BiologicalProcess bacterial cellulose biosynthetic process The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria. go-plus.json bacterial cellulose biosynthesis http://purl.obolibrary.org/obo/GO_0090540 GO:0090543 biolink:CellularComponent Flemming body A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge. go-plus.json Midbody ring http://purl.obolibrary.org/obo/GO_0090543 GO:0090544 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090544 GO:0090541 biolink:MolecularActivity MIT domain binding Binding to a MIT protein domain. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking. go-plus.json http://purl.obolibrary.org/obo/GO_0090541 GO:0090542 biolink:MolecularActivity ELYC domain binding Binding to a ELYC protein domain. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC. go-plus.json http://purl.obolibrary.org/obo/GO_0090542 GO:0090558 biolink:BiologicalProcess plant epidermis development The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0090558 GO:0090559 biolink:BiologicalProcess regulation of membrane permeability Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090559 GO:0090556 biolink:MolecularActivity phosphatidylserine floppase activity Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. RHEA:38567 go-plus.json ATPase-dependent phosphatidylserine transporter activity|phosphatidylserine floppase activity (cytosolic to exoplasmic leaftlet)|phosphatidylserine-translocating ATPase activity|ATPase-coupled phosphatidylserine transporter activity http://purl.obolibrary.org/obo/GO_0090556 GO:0090557 biolink:BiologicalProcess establishment of endothelial intestinal barrier The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. go-plus.json http://purl.obolibrary.org/obo/GO_0090557 GO:0090550 biolink:BiologicalProcess response to molybdenum starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum. go-plus.json http://purl.obolibrary.org/obo/GO_0090550 GO:0090551 biolink:BiologicalProcess response to manganese starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese. go-plus.json http://purl.obolibrary.org/obo/GO_0090551 GO:0090554 biolink:MolecularActivity phosphatidylcholine floppase activity Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. RHEA:38583 go-plus.json phosphatidylcholine-translocating ATPase activity|ATPase-coupled phosphatidylcholine transporter activity|ATP-dependent phosphatidylcholine transporter activity|phosphatidylcholine floppase activity (cytosolic to exoplasmic leaftlet) http://purl.obolibrary.org/obo/GO_0090554 GO:0090555 biolink:MolecularActivity phosphatidylethanolamine flippase activity Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. RHEA:66132 go-plus.json ATP-dependent phosphatidylethanolamine transporter activity|ATPase-coupled phosphatidylethanolamine transporter activity|phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)|phosphatidylethanolamine-translocating ATPase activity http://purl.obolibrary.org/obo/GO_0090555 GO:0090552 biolink:CellularComponent unicellular trichome apex A cell projection part that is the apical most portion of a unicellular trichome. go-plus.json http://purl.obolibrary.org/obo/GO_0090552 GO:0090553 biolink:CellularComponent unicellular trichome tip A cell projection part that is the apical most portion of a unicellular trichome apex. go-plus.json http://purl.obolibrary.org/obo/GO_0090553 NCBITaxon:28781 biolink:OrganismalEntity Adrianichthyoidei go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_28781 CHEBI:5130 biolink:ChemicalSubstance flurbiprofen go-plus.json http://purl.obolibrary.org/obo/CHEBI_5130 GO:0090580 biolink:MolecularActivity phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand. go-plus.json http://purl.obolibrary.org/obo/GO_0090580 GO:0090589 biolink:MolecularActivity protein-phosphocysteine-trehalose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in). go-plus.json http://purl.obolibrary.org/obo/GO_0090589 GO:0090583 biolink:MolecularActivity protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090583 GO:0090584 biolink:MolecularActivity protein-phosphocysteine-galactitol-phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090584 GO:0090581 biolink:MolecularActivity protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090581 GO:0090582 biolink:MolecularActivity protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090582 GO:0090587 biolink:MolecularActivity protein-phosphocysteine-glucosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in). go-plus.json http://purl.obolibrary.org/obo/GO_0090587 GO:0090588 biolink:MolecularActivity protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in). go-plus.json http://purl.obolibrary.org/obo/GO_0090588 GO:0090585 biolink:MolecularActivity protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090585 GO:0090586 biolink:MolecularActivity protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in). go-plus.json http://purl.obolibrary.org/obo/GO_0090586 CHEBI:149778 biolink:ChemicalSubstance methyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_149778 CHEBI:149779 biolink:ChemicalSubstance Mannogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_149779 GO:0090590 biolink:MolecularActivity protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090590 GO:0090591 biolink:MolecularActivity protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090591 CHEBI:5118 biolink:ChemicalSubstance fluoxetine go-plus.json http://purl.obolibrary.org/obo/CHEBI_5118 CHEBI:5115 biolink:ChemicalSubstance monofluorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_5115 chebi_ph7_3 GO:0090594 biolink:BiologicalProcess inflammatory response to wounding The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. go-plus.json http://purl.obolibrary.org/obo/GO_0090594 GO:0090595 biolink:MolecularActivity acetyl-CoA:L-lysine N6-acetyltransferase Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H(+). go-plus.json http://purl.obolibrary.org/obo/GO_0090595 GO:0090592 biolink:BiologicalProcess DNA synthesis involved in DNA replication Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0090592 GO:0090593 biolink:BiologicalProcess peptidyl-histidine autophosphorylation The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090593 GO:0090598 biolink:BiologicalProcess male anatomical structure morphogenesis The processes by which anatomical structures that are only present in the male organism are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0090598 GO:0090599 biolink:MolecularActivity alpha-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose. Reactome:R-HSA-9036729|Reactome:R-HSA-9036727|EC:3.2.1.20 go-plus.json http://purl.obolibrary.org/obo/GO_0090599 GO:0090596 biolink:BiologicalProcess sensory organ morphogenesis Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json http://purl.obolibrary.org/obo/GO_0090596 GO:0090597 biolink:BiologicalProcess nematode male tail mating organ morphogenesis The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules. go-plus.json http://purl.obolibrary.org/obo/GO_0090597 CHEBI:65072 biolink:ChemicalSubstance carboxyspermidine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65072 chebi_ph7_3 CHEBI:65073 biolink:ChemicalSubstance C20 3-dehydrosphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65073 chebi_ph7_3 CHEBI:65074 biolink:ChemicalSubstance N-hexacosanoyl-C20-4-hydroxysphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65074 chebi_ph7_3 CHEBI:65075 biolink:ChemicalSubstance 2'-deamino-2'-hydroxyparomamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65075 CHEBI:5171 biolink:ChemicalSubstance friedelin go-plus.json http://purl.obolibrary.org/obo/CHEBI_5171 chebi_ph7_3 CHEBI:65070 biolink:ChemicalSubstance carboxynorspermidine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65070 chebi_ph7_3 CHEBI:65071 biolink:ChemicalSubstance 2'-deamino-2'-hydroxyparomamine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65071 chebi_ph7_3 CHEBI:65076 biolink:ChemicalSubstance neamine(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65076 chebi_ph7_3 CHEBI:65077 biolink:ChemicalSubstance neomycin C(6+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65077 chebi_ph7_3 CHEBI:65078 biolink:ChemicalSubstance isopentenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65078 chebi_ph7_3 CHEBI:65079 biolink:ChemicalSubstance trans,polycis-decaprenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65079 chebi_ph7_3 CHEBI:65084 biolink:ChemicalSubstance 2-hydroxyoctadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_65084 chebi_ph7_3 CHEBI:65085 biolink:ChemicalSubstance butirosin B(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65085 chebi_ph7_3 CHEBI:65086 biolink:ChemicalSubstance gamma-L-glutamylbutirosin B(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65086 chebi_ph7_3 CHEBI:65080 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,polycis-decaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65080 chebi_ph7_3 CHEBI:65081 biolink:ChemicalSubstance 2-oxo-3-(5-oxofuran-2-ylidene)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_65081 chebi_ph7_3 CHEBI:65082 biolink:ChemicalSubstance 5''-phosphoribostamycin(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65082 chebi_ph7_3 CHEBI:31746 biolink:ChemicalSubstance kainic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31746 CHEBI:65087 biolink:ChemicalSubstance (9Z)-myristoleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65087 CHEBI:65088 biolink:ChemicalSubstance docosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_65088 CHEBI:31748 biolink:ChemicalSubstance 3-amino-3-deoxy-6-O-phosphono-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_31748 CHEBI:65089 biolink:ChemicalSubstance Ins-1-P-Cer(d18:0/26:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65089 chebi_ph7_3 GO:1905300 biolink:BiologicalProcess positive regulation of intestinal epithelial cell development Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development. go-plus.json up regulation of intestinal epithelial cell development|upregulation of intestinal epithelial cell development|up-regulation of intestinal epithelial cell development|activation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_1905300 CHEBI:90029 biolink:ChemicalSubstance PS(16:0/20:4(5Z,8Z,11Z,14Z)) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90029 CHEBI:31742 biolink:ChemicalSubstance kaempferol 3-O-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_31742 CHEBI:65094 biolink:ChemicalSubstance Ins-1-P-Cer(d18:0/2-OH-26:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65094 chebi_ph7_3 CHEBI:65096 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-arabinofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_65096 CHEBI:65097 biolink:ChemicalSubstance 2-hydroxyhexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_65097 chebi_ph7_3 CHEBI:65090 biolink:ChemicalSubstance 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_65090 CHEBI:65091 biolink:ChemicalSubstance Ins-1-P-Cer(d18:0/24:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65091 chebi_ph7_3 CHEBI:65092 biolink:ChemicalSubstance 1-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65092 chebi_ph7_3 CHEBI:65098 biolink:ChemicalSubstance 6'''-oxoneomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_65098 GO:1905310 biolink:BiologicalProcess regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905310 GO:1905311 biolink:BiologicalProcess negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. go-plus.json downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis|down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1905311 GO:1905301 biolink:BiologicalProcess regulation of macropinocytosis Any process that modulates the frequency, rate or extent of macropinocytosis. go-plus.json regulation of clathrin-independent pinocytosis http://purl.obolibrary.org/obo/GO_1905301 GO:1905302 biolink:BiologicalProcess negative regulation of macropinocytosis Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis. go-plus.json down-regulation of macropinocytosis|downregulation of macropinocytosis|down regulation of macropinocytosis|inhibition of macropinocytosis http://purl.obolibrary.org/obo/GO_1905302 CHEBI:16119 biolink:ChemicalSubstance shikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16119 GO:1905303 biolink:BiologicalProcess positive regulation of macropinocytosis Any process that activates or increases the frequency, rate or extent of macropinocytosis. go-plus.json up regulation of macropinocytosis|upregulation of macropinocytosis|up-regulation of macropinocytosis|activation of macropinocytosis http://purl.obolibrary.org/obo/GO_1905303 GO:1905304 biolink:BiologicalProcess regulation of cardiac myofibril assembly Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. go-plus.json regulation of cardiac myofibril morphogenesis|regulation of cardiac myofibril development|regulation of heart myofibril assembly http://purl.obolibrary.org/obo/GO_1905304 GO:1905305 biolink:BiologicalProcess negative regulation of cardiac myofibril assembly Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. go-plus.json down regulation of cardiac myofibril morphogenesis|down regulation of cardiac myofibril assembly|inhibition of cardiac myofibril assembly|negative regulation of heart myofibril assembly|downregulation of cardiac myofibril morphogenesis|down-regulation of heart myofibril assembly|down regulation of cardiac myofibril development|downregulation of cardiac myofibril development|negative regulation of cardiac myofibril morphogenesis|downregulation of heart myofibril assembly|down-regulation of cardiac myofibril morphogenesis|down regulation of heart myofibril assembly|down-regulation of cardiac myofibril development|negative regulation of cardiac myofibril development|down-regulation of cardiac myofibril assembly|inhibition of cardiac myofibril morphogenesis|inhibition of heart myofibril assembly|inhibition of cardiac myofibril development|downregulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1905305 GO:1905306 biolink:BiologicalProcess positive regulation of cardiac myofibril assembly Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. go-plus.json upregulation of cardiac myofibril morphogenesis|activation of heart myofibril assembly|upregulation of cardiac myofibril development|upregulation of cardiac myofibril assembly|up regulation of cardiac myofibril morphogenesis|positive regulation of heart myofibril assembly|activation of cardiac myofibril morphogenesis|up regulation of heart myofibril assembly|positive regulation of cardiac myofibril morphogenesis|activation of cardiac myofibril assembly|up regulation of cardiac myofibril development|up-regulation of cardiac myofibril assembly|activation of cardiac myofibril development|positive regulation of cardiac myofibril development|upregulation of heart myofibril assembly|up-regulation of cardiac myofibril morphogenesis|up regulation of cardiac myofibril assembly|up-regulation of cardiac myofibril development|up-regulation of heart myofibril assembly http://purl.obolibrary.org/obo/GO_1905306 CHEBI:16118 biolink:ChemicalSubstance berberine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16118 chebi_ph7_3 GO:1905307 biolink:BiologicalProcess response to miconazole Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905307 GO:1905308 biolink:BiologicalProcess cellular response to miconazole Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905308 CHEBI:16116 biolink:ChemicalSubstance 3-hydroxy-4-methylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16116 GO:1905309 biolink:BiologicalProcess positive regulation of cohesin loading Any process that activates or increases the frequency, rate or extent of cohesin loading. go-plus.json positive regulation of cohesin localization to chromatin|positive regulation of cohesin association with chromatin http://purl.obolibrary.org/obo/GO_1905309 CHEBI:16113 biolink:ChemicalSubstance cholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16113 chebi_ph7_3 CHEBI:16114 biolink:ChemicalSubstance medicarpin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16114 chebi_ph7_3 CHEBI:16111 biolink:ChemicalSubstance nonane-4,6-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16111 chebi_ph7_3 CHEBI:16112 biolink:ChemicalSubstance chlorogenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16112 CHEBI:16110 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16110 GO:1905320 biolink:BiologicalProcess regulation of mesenchymal stem cell migration Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_1905320 GO:1905321 biolink:BiologicalProcess negative regulation of mesenchymal stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration. go-plus.json down regulation of mesenchymal stem cell migration|downregulation of mesenchymal stem cell migration|down-regulation of mesenchymal stem cell migration|inhibition of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_1905321 GO:1905322 biolink:BiologicalProcess positive regulation of mesenchymal stem cell migration Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration. go-plus.json upregulation of mesenchymal stem cell migration|up regulation of mesenchymal stem cell migration|activation of mesenchymal stem cell migration|up-regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_1905322 GO:1905312 biolink:BiologicalProcess positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. go-plus.json up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|activation of cardiac neural crest cell migration involved in outflow tract morphogenesis|up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1905312 GO:1905313 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in heart development Any transforming growth factor beta receptor signaling pathway that is involved in heart development. go-plus.json TGF-beta receptor signalling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in dorsal vessel development|TGFbeta receptor signalling pathway involved in heart development|transforming growth factor beta receptor signalling pathway involved in cardiac development|TGFbeta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in cardiac development|transforming growth factor beta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in cardiac development|TGF-beta receptor signalling pathway involved in cardiac development|TGFbeta receptor signalling pathway involved in cardiac development|transforming growth factor beta receptor signaling pathway involved in cardiac development|transforming growth factor beta receptor signalling pathway involved in heart development|TGFbeta receptor signaling pathway involved in heart development|transforming growth factor beta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in heart development|TGF-beta receptor signalling pathway involved in heart development http://purl.obolibrary.org/obo/GO_1905313 GO:1905314 biolink:BiologicalProcess semi-lunar valve development The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure. go-plus.json semilunar valve development|semilunar valves development http://purl.obolibrary.org/obo/GO_1905314 CHEBI:16108 biolink:ChemicalSubstance dihydroxyacetone phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16108 CHEBI:16109 biolink:ChemicalSubstance propane-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16109 chebi_ph7_3 GO:1905315 biolink:BiologicalProcess cell proliferation involved in endocardial cushion morphogenesis Any cell proliferation that is involved in endocardial cushion morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905315 GO:1905316 biolink:BiologicalProcess superior endocardial cushion morphogenesis The developmental process by which a superior endocardial cushion is generated and organized. go-plus.json dorsal endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_1905316 CHEBI:16106 biolink:ChemicalSubstance 2,4-dichloro-5-oxo-2,5-dihydro-2-furylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16106 GO:1905317 biolink:BiologicalProcess inferior endocardial cushion morphogenesis The developmental process by which an inferior endocardial cushion is generated and organized. go-plus.json ventral endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_1905317 GO:1905318 biolink:BiologicalProcess meiosis I spindle assembly checkpoint signaling Any spindle assembly checkpoint that is involved in meiosis I. go-plus.json meiosis I spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_1905318 CHEBI:16104 biolink:ChemicalSubstance 3-(2-hydroxyphenyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16104 GO:1905319 biolink:BiologicalProcess mesenchymal stem cell migration The orderly movement of a mesenchymal stem cell from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_1905319 CHEBI:16100 biolink:ChemicalSubstance 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16100 CHEBI:16101 biolink:ChemicalSubstance ethylbenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16101 chebi_ph7_3 GO:1905330 biolink:BiologicalProcess regulation of morphogenesis of an epithelium Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. go-plus.json regulation of epithelium morphogenesis http://purl.obolibrary.org/obo/GO_1905330 GO:1905331 biolink:BiologicalProcess negative regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. go-plus.json down-regulation of morphogenesis of an epithelium|negative regulation of epithelium morphogenesis|down-regulation of epithelium morphogenesis|downregulation of morphogenesis of an epithelium|down regulation of morphogenesis of an epithelium|inhibition of morphogenesis of an epithelium|downregulation of epithelium morphogenesis|down regulation of epithelium morphogenesis|inhibition of epithelium morphogenesis http://purl.obolibrary.org/obo/GO_1905331 GO:1905332 biolink:BiologicalProcess positive regulation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. go-plus.json up-regulation of epithelium morphogenesis|activation of epithelium morphogenesis|up regulation of morphogenesis of an epithelium|positive regulation of epithelium morphogenesis|up regulation of epithelium morphogenesis|upregulation of morphogenesis of an epithelium|upregulation of epithelium morphogenesis|up-regulation of morphogenesis of an epithelium|activation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905332 GO:1905333 biolink:BiologicalProcess regulation of gastric motility Any process that modulates the frequency, rate or extent of gastric motility. go-plus.json http://purl.obolibrary.org/obo/GO_1905333 GO:1905323 biolink:BiologicalProcess telomerase holoenzyme complex assembly The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex. go-plus.json telomerase holoenzyme complex formation http://purl.obolibrary.org/obo/GO_1905323 GO:0090525 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090525 GO:1905324 biolink:BiologicalProcess telomere-telomerase complex assembly The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex. go-plus.json telomere-telomerase complex formation http://purl.obolibrary.org/obo/GO_1905324 GO:0090526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090526 GO:1905325 biolink:BiologicalProcess regulation of meiosis I spindle assembly checkpoint Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_1905325 GO:0090523 biolink:MolecularActivity cytochrome-b5 reductase activity, acting on NADPH Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5). RHEA:64576 go-plus.json cytochrome-b5 reductase activity http://purl.obolibrary.org/obo/GO_0090523 GO:0090524 biolink:MolecularActivity cytochrome-b5 reductase activity, acting on NADH Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5). go-plus.json cytochrome b5 reductase activity http://purl.obolibrary.org/obo/GO_0090524 GO:1905326 biolink:BiologicalProcess positive regulation of meiosis I spindle assembly checkpoint Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint. go-plus.json up-regulation of meiosis I spindle assembly checkpoint|upregulation of meiosis I spindle assembly checkpoint|up regulation of meiosis I spindle assembly checkpoint|activation of meiosis I spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_1905326 GO:0090529 biolink:BiologicalProcess cell septum assembly The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. go-plus.json cell septum assembly involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_0090529 GO:1905327 biolink:BiologicalProcess tracheoesophageal septum formation The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json tracheoesophageal ridges formation|esophagotracheal septum formation http://purl.obolibrary.org/obo/GO_1905327 GO:1905328 biolink:BiologicalProcess plant septum development The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure. go-plus.json dissepiment development http://purl.obolibrary.org/obo/GO_1905328 GO:1905329 biolink:BiologicalProcess sphingoid long-chain base transport The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast. go-plus.json sphingosine transport|sphingoid base(1+) transport|dihydrosphingosine transport|long-chain base transport|sphingoid transport|phytosphingosine transport http://purl.obolibrary.org/obo/GO_1905329 GO:0090527 biolink:BiologicalProcess actin filament reorganization A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0090527 GO:0090528 biolink:BiologicalProcess smooth septate junction assembly The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0090528 GO:0090521 biolink:BiologicalProcess glomerular visceral epithelial cell migration The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. go-plus.json podocyte cell migration http://purl.obolibrary.org/obo/GO_0090521 CHEBI:90076 biolink:ChemicalSubstance (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90076 chebi_ph7_3 GO:0090522 biolink:BiologicalProcess vesicle tethering involved in exocytosis The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. go-plus.json vesicle tethering to plasma membrane http://purl.obolibrary.org/obo/GO_0090522 CHEBI:90077 biolink:ChemicalSubstance arachidonoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90077 chebi_ph7_3 CHEBI:90078 biolink:ChemicalSubstance alpha-linolenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90078 chebi_ph7_3 GO:0090520 biolink:BiologicalProcess sphingolipid mediated signaling pathway A series of molecular signals mediated by a sphingolipid. go-plus.json sphingolipid signaling pathway|ceramide 1-phosphate signaling pathway|ceramide signaling pathway|sphingolipid mediated signal transduction|sphingolipid-mediated signaling pathway|sphingosine signaling pathway http://purl.obolibrary.org/obo/GO_0090520 CHEBI:90079 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90079 chebi_ph7_3 GO:1905340 biolink:BiologicalProcess regulation of protein localization to kinetochore Any process that modulates the frequency, rate or extent of protein localization to kinetochore. go-plus.json regulation of protein localisation to kinetochore|regulation of condensin localization to kinetochore http://purl.obolibrary.org/obo/GO_1905340 GO:1905341 biolink:BiologicalProcess negative regulation of protein localization to kinetochore Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore. go-plus.json downregulation of protein localization to kinetochore|down regulation of protein localisation to kinetochore|inhibition of condensin localization to kinetochore|downregulation of protein localisation to kinetochore|down-regulation of protein localization to kinetochore|down regulation of condensin localization to kinetochore|inhibition of protein localization to kinetochore|down-regulation of protein localisation to kinetochore|downregulation of condensin localization to kinetochore|negative regulation of protein localisation to kinetochore|inhibition of protein localisation to kinetochore|negative regulation of condensin localization to kinetochore|down-regulation of condensin localization to kinetochore|down regulation of protein localization to kinetochore http://purl.obolibrary.org/obo/GO_1905341 GO:1905342 biolink:BiologicalProcess positive regulation of protein localization to kinetochore Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore. go-plus.json upregulation of protein localisation to kinetochore|up-regulation of condensin localization to kinetochore|up regulation of protein localization to kinetochore|activation of protein localization to kinetochore|upregulation of condensin localization to kinetochore|up regulation of protein localisation to kinetochore|positive regulation of protein localisation to kinetochore|activation of protein localisation to kinetochore|up-regulation of protein localization to kinetochore|up regulation of condensin localization to kinetochore|positive regulation of condensin localization to kinetochore|up-regulation of protein localisation to kinetochore|upregulation of protein localization to kinetochore|activation of condensin localization to kinetochore http://purl.obolibrary.org/obo/GO_1905342 GO:1905343 biolink:BiologicalProcess regulation of cohesin unloading Any process that modulates the frequency, rate or extent of cohesin unloading. go-plus.json http://purl.obolibrary.org/obo/GO_1905343 GO:1905344 biolink:BiologicalProcess prostaglandin catabolic process The chemical reactions and pathways resulting in the breakdown of prostaglandin. go-plus.json prostaglandin catabolism|prostaglandin degradation|prostaglandin breakdown http://purl.obolibrary.org/obo/GO_1905344 GO:0090536 biolink:CellularComponent NoRC complex An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0090536 GO:1905334 biolink:MolecularActivity Swi5-Sfr1 complex binding Binding to a Swi5-Sfr1 complex. go-plus.json Sae3-Mei5 complex binding http://purl.obolibrary.org/obo/GO_1905334 GO:0090537 biolink:CellularComponent CERF complex An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0090537 GO:1905335 biolink:BiologicalProcess regulation of aggrephagy Any process that modulates the frequency, rate or extent of aggrephagy. go-plus.json http://purl.obolibrary.org/obo/GO_1905335 GO:1905336 biolink:BiologicalProcess negative regulation of aggrephagy Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy. go-plus.json down-regulation of aggrephagy|downregulation of aggrephagy|down regulation of aggrephagy|inhibition of aggrephagy http://purl.obolibrary.org/obo/GO_1905336 GO:0090534 biolink:CellularComponent calcium ion-transporting ATPase complex Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090534 GO:0090535 biolink:CellularComponent WICH complex An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair. go-plus.json http://purl.obolibrary.org/obo/GO_0090535 GO:1905337 biolink:BiologicalProcess positive regulation of aggrephagy Any process that activates or increases the frequency, rate or extent of aggrephagy. go-plus.json up-regulation of aggrephagy|activation of aggrephagy|up regulation of aggrephagy|upregulation of aggrephagy http://purl.obolibrary.org/obo/GO_1905337 GO:1905338 biolink:BiologicalProcess negative regulation of cohesin unloading Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading. go-plus.json inhibition of cohesin unloading|down regulation of cohesin unloading|downregulation of cohesin unloading|down-regulation of cohesin unloading http://purl.obolibrary.org/obo/GO_1905338 GO:1905339 biolink:BiologicalProcess positive regulation of cohesin unloading Any process that activates or increases the frequency, rate or extent of cohesin unloading. go-plus.json up-regulation of cohesin unloading|upregulation of cohesin unloading|up regulation of cohesin unloading|activation of cohesin unloading http://purl.obolibrary.org/obo/GO_1905339 GO:0090538 biolink:BiologicalProcess peptide pheromone secretion The regulated release of a peptide pheromone from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090538 GO:0090539 biolink:BiologicalProcess peptide pheromone export by transmembrane transport The directed movement of a peptide pheromone across a membrane and out of a cell. go-plus.json peptide pheromone export by membrane transport http://purl.obolibrary.org/obo/GO_0090539 NCBITaxon:4232 biolink:OrganismalEntity Helianthus annuus go-plus.json common sunflower http://purl.obolibrary.org/obo/NCBITaxon_4232 NCBITaxon:4231 biolink:OrganismalEntity Helianthus go-plus.json sunflowers http://purl.obolibrary.org/obo/NCBITaxon_4231 GO:0090532 biolink:BiologicalProcess L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate. go-plus.json L-ascorbic acid biosynthesis via UDP-alpha-D-glucuronate http://purl.obolibrary.org/obo/GO_0090532 GO:0090533 biolink:CellularComponent cation-transporting ATPase complex Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in). go-plus.json http://purl.obolibrary.org/obo/GO_0090533 GO:0090530 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090530 GO:0090531 biolink:BiologicalProcess L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose. BioCyc:PWY-882 go-plus.json L-ascorbic acid biosynthesis via GDP-alpha-D-mannose|Smirnoff-Wheeler's pathway http://purl.obolibrary.org/obo/GO_0090531 CHEBI:90095 biolink:ChemicalSubstance 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90095 CHEBI:90092 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90092 CHEBI:90093 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90093 GO:1905350 biolink:BiologicalProcess Y-shaped link assembly The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate. go-plus.json Y-shaped assemblage formation|Y-link structure assembly|Y-shaped fiber assembly|Y-shaped linker formation|membrane-microtubule complex assembly|Y-link formation|Y-shaped fibre assembly|Y-shaped fibre formation|Y-shaped link formation|membrane-microtubule complex formation|Y-link assembly|Y-shaped linker assembly|Y-shaped fiber formation|Y-link structure formation|Y-shaped assemblage assembly http://purl.obolibrary.org/obo/GO_1905350 GO:1905351 biolink:BiologicalProcess pericyte cell migration The orderly movement of a pericyte cell from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_1905351 GO:1905352 biolink:BiologicalProcess ciliary necklace assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace. go-plus.json cilium necklace assembly|ciliary necklace formation|cilial necklace assembly|cilial necklace formation|cilium necklace formation http://purl.obolibrary.org/obo/GO_1905352 GO:1905353 biolink:BiologicalProcess ciliary transition fiber assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber. go-plus.json cilial transition fibre formation|cilial transition fiber formation|ciliary transition fibre assembly|cilium transition fiber assembly|distal appendage of basal body assembly|cilium transition fibre formation|cilium transition fibre assembly|centriolar distal appendage assembly|cilium transition fiber formation|distal appendage of mother centriole formation|distal appendage of centriole assembly|distal appendage of centriole formation|distal appendage of mother centriole assembly|centriolar distal appendage formation|ciliary transition fibre formation|cilial transition fiber assembly|distal appendage of basal body formation|cilial transition fibre assembly|ciliary transition fiber formation http://purl.obolibrary.org/obo/GO_1905353 GO:1905354 biolink:CellularComponent exoribonuclease complex A protein complex which is capable of exoribonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905354 GO:1905355 biolink:BiologicalProcess spine apparatus assembly The aggregation, arrangement and bonding together of a set of components to form a spine apparatus. go-plus.json dense material assembly|dense material formation|spine apparatus formation http://purl.obolibrary.org/obo/GO_1905355 GO:1905345 biolink:BiologicalProcess protein localization to cleavage furrow A process in which a protein is transported to, or maintained in, a location within a cleavage furrow. go-plus.json protein localization in cleavage furrow|protein localisation in cleavage furrow|protein localisation to cleavage furrow http://purl.obolibrary.org/obo/GO_1905345 GO:0090503 biolink:BiologicalProcess RNA phosphodiester bond hydrolysis, exonucleolytic The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides. go-plus.json http://purl.obolibrary.org/obo/GO_0090503 GO:1905346 biolink:BiologicalProcess protein localization to cleavage furrow rim A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim. go-plus.json protein localisation to cleavage furrow rim|protein localization in cleavage furrow rim|protein localisation in cleavage furrow rim http://purl.obolibrary.org/obo/GO_1905346 GO:0090504 biolink:BiologicalProcess epiboly The expansion of one cell sheet over other cells or yolk. go-plus.json http://purl.obolibrary.org/obo/GO_0090504 GO:1905347 biolink:CellularComponent endodeoxyribonuclease complex A protein complex which is capable of endodeoxyribonuclease activity. go-plus.json Mus81-Eme2 complex|Mus81-Eme1 complex http://purl.obolibrary.org/obo/GO_1905347 GO:0090501 biolink:BiologicalProcess RNA phosphodiester bond hydrolysis The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0090501 GO:1905348 biolink:CellularComponent endonuclease complex A protein complex which is capable of endonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905348 GO:0090502 biolink:BiologicalProcess RNA phosphodiester bond hydrolysis, endonucleolytic The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides. go-plus.json http://purl.obolibrary.org/obo/GO_0090502 GO:1905349 biolink:BiologicalProcess ciliary transition zone assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. go-plus.json cilial transition zone formation|cilium transition zone assembly|ciliary transition zone formation|cilium transition zone formation|cilial transition zone assembly http://purl.obolibrary.org/obo/GO_1905349 GO:0090507 biolink:BiologicalProcess phenylethylamine metabolic process involved in synaptic transmission The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0090507 GO:0090508 biolink:BiologicalProcess phenylethylamine biosynthetic process involved in synaptic transmission The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0090508 GO:0090505 biolink:BiologicalProcess epiboly involved in wound healing The expansion of one cell sheet over other cells involved in wound healing. go-plus.json http://purl.obolibrary.org/obo/GO_0090505 GO:0090506 biolink:BiologicalProcess axillary shoot meristem initiation A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf. go-plus.json axillary bud meristem initiation http://purl.obolibrary.org/obo/GO_0090506 GO:0090500 biolink:BiologicalProcess endocardial cushion to mesenchymal transition A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090500 CHEBI:90099 biolink:ChemicalSubstance carboxyphosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90099 CHEBI:90083 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90083 chebi_ph7_3 CHEBI:90085 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90085 chebi_ph7_3 CHEBI:90086 biolink:ChemicalSubstance N-benzoyl-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_90086 CHEBI:90081 biolink:ChemicalSubstance gamma-linolenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90081 chebi_ph7_3 CHEBI:90082 biolink:ChemicalSubstance omega-3-arachidonoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_90082 chebi_ph7_3 GO:1905360 biolink:CellularComponent GTPase complex A protein complex which is capable of GTPase activity. go-plus.json HRAS-SOS1 complex|RASH-SOS1 complex http://purl.obolibrary.org/obo/GO_1905360 GO:1905361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905361 GO:0090509 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090509 GO:1905362 biolink:BiologicalProcess negative regulation of endosomal vesicle fusion Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion. go-plus.json down regulation of endosomal vesicle fusion|inhibition of endosomal vesicle fusion|down regulation of endosome vesicle fusion|downregulation of endosome vesicle fusion|negative regulation of endosome vesicle fusion|down-regulation of endosome vesicle fusion|down-regulation of endosomal vesicle fusion|inhibition of endosome vesicle fusion|downregulation of endosomal vesicle fusion http://purl.obolibrary.org/obo/GO_1905362 GO:1905363 biolink:BiologicalProcess positive regulation of endosomal vesicle fusion Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion. go-plus.json upregulation of endosome vesicle fusion|upregulation of endosomal vesicle fusion|up regulation of endosome vesicle fusion|activation of endosome vesicle fusion|positive regulation of endosome vesicle fusion|activation of endosomal vesicle fusion|up-regulation of endosomal vesicle fusion|up-regulation of endosome vesicle fusion|up regulation of endosomal vesicle fusion http://purl.obolibrary.org/obo/GO_1905363 GO:1905364 biolink:BiologicalProcess regulation of endosomal vesicle fusion Any process that modulates the frequency, rate or extent of endosomal vesicle fusion. go-plus.json regulation of endosome vesicle fusion http://purl.obolibrary.org/obo/GO_1905364 GO:1905365 biolink:BiologicalProcess regulation of intralumenal vesicle formation Any process that modulates the frequency, rate or extent of intralumenal vesicle formation. go-plus.json regulation of endosome membrane budding http://purl.obolibrary.org/obo/GO_1905365 NCBITaxon:4209 biolink:OrganismalEntity Asterales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4209 GO:1905366 biolink:BiologicalProcess negative regulation of intralumenal vesicle formation Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation. go-plus.json downregulation of intralumenal vesicle formation|inhibition of endosome membrane budding|down regulation of intralumenal vesicle formation|inhibition of intralumenal vesicle formation|down regulation of endosome membrane budding|downregulation of endosome membrane budding|down-regulation of intralumenal vesicle formation|down-regulation of endosome membrane budding|negative regulation of endosome membrane budding http://purl.obolibrary.org/obo/GO_1905366 GO:1905356 biolink:BiologicalProcess regulation of snRNA pseudouridine synthesis Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905356 GO:0090514 biolink:BiologicalProcess L-tyrosine transmembrane import into vacuole The directed movement of L-tyrosine into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090514 GO:1905357 biolink:BiologicalProcess negative regulation of snRNA pseudouridine synthesis Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis. go-plus.json down-regulation of snRNA pseudouridine synthesis|inhibition of snRNA pseudouridine synthesis|down regulation of snRNA pseudouridine synthesis|downregulation of snRNA pseudouridine synthesis http://purl.obolibrary.org/obo/GO_1905357 GO:0090515 biolink:BiologicalProcess L-glutamate transmembrane import into vacuole The directed movement of L-glutamate into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090515 GO:1905358 biolink:BiologicalProcess positive regulation of snRNA pseudouridine synthesis Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis. go-plus.json activation of snRNA pseudouridine synthesis|up-regulation of snRNA pseudouridine synthesis|upregulation of snRNA pseudouridine synthesis|up regulation of snRNA pseudouridine synthesis http://purl.obolibrary.org/obo/GO_1905358 GO:0090512 biolink:CellularComponent eisosome membrane domain/MCC A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0090512 GO:1905359 biolink:BiologicalProcess protein localization to meiotic spindle A process in which a protein is transported to, or maintained in, a location within a meiotic spindle. go-plus.json protein localisation to meiotic spindle http://purl.obolibrary.org/obo/GO_1905359 GO:0090513 biolink:BiologicalProcess L-histidine transmembrane import into vacuole The directed movement of L-histidine into the vacuole across the vacuolar membrane. go-plus.json histidine transmembrane import into vacuole|vacuolar histidine import http://purl.obolibrary.org/obo/GO_0090513 GO:0090518 biolink:BiologicalProcess L-arginine transmembrane import into vacuole The directed movement of L-arginine into the vacuole across the vacuolar membrane. go-plus.json arginine transmembrane import into vacuole|vacuolar arginine import http://purl.obolibrary.org/obo/GO_0090518 GO:0090519 biolink:BiologicalProcess anoxia protection Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia. go-plus.json http://purl.obolibrary.org/obo/GO_0090519 GO:0090516 biolink:BiologicalProcess L-serine transmembrane import into vacuole The directed movement of L-serine into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090516 GO:0090517 biolink:BiologicalProcess L-lysine transmembrane import into vacuole The directed movement of L-lysine into the vacuole across the vacuolar membrane. go-plus.json lysine transmembrane import into vacuole|vacuolar lysine import http://purl.obolibrary.org/obo/GO_0090517 IAO:0000589 biolink:OntologyClass OBO foundry unique label go-plus.json http://purl.obolibrary.org/obo/IAO_0000589 NCBITaxon:4210 biolink:OrganismalEntity Asteraceae go-plus.json Compositae|daisy family http://purl.obolibrary.org/obo/NCBITaxon_4210 GO:0090510 biolink:BiologicalProcess anticlinal cell division A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file. go-plus.json http://purl.obolibrary.org/obo/GO_0090510 GO:0090511 biolink:BiologicalProcess periclinal cell division A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file. go-plus.json http://purl.obolibrary.org/obo/GO_0090511 CHEBI:16062 biolink:ChemicalSubstance N-acyl-D-mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16062 chebi_ph7_3 CHEBI:16060 biolink:ChemicalSubstance 10-deoxysarpagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16060 chebi_ph7_3 GO:2000346 biolink:BiologicalProcess negative regulation of hepatocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000346 GO:2000347 biolink:BiologicalProcess positive regulation of hepatocyte proliferation Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000347 GO:2000348 biolink:BiologicalProcess regulation of CD40 signaling pathway Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway. go-plus.json regulation of CD40 signalling pathway http://purl.obolibrary.org/obo/GO_2000348 GO:2000349 biolink:BiologicalProcess negative regulation of CD40 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway. go-plus.json negative regulation of CD40 signalling pathway http://purl.obolibrary.org/obo/GO_2000349 GO:0016507 biolink:CellularComponent mitochondrial fatty acid beta-oxidation multienzyme complex A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix. go-plus.json trifunctional enzyme|fatty acid beta-oxidation multienzyme complex http://purl.obolibrary.org/obo/GO_0016507 GO:0016508 biolink:MolecularActivity long-chain-enoyl-CoA hydratase activity Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms. Reactome:R-HSA-390252|Reactome:R-HSA-2066778|EC:4.2.1.74|MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN|Reactome:R-HSA-2066780|Reactome:R-HSA-389986|Reactome:R-HSA-6809263 go-plus.json long-chain enoyl coenzyme A hydratase activity|long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity http://purl.obolibrary.org/obo/GO_0016508 GO:0016509 biolink:MolecularActivity long-chain-3-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. Reactome:R-HSA-548818|MetaCyc:1.1.1.211-RXN|EC:1.1.1.211 go-plus.json long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity|LCHAD|long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity|beta-hydroxyacyl-CoA dehydrogenase activity http://purl.obolibrary.org/obo/GO_0016509 GO:0016503 biolink:MolecularActivity pheromone receptor activity Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior. go-plus.json http://purl.obolibrary.org/obo/GO_0016503 GO:0016504 biolink:MolecularActivity peptidase activator activity Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. Reactome:R-HSA-168865 go-plus.json protease activator activity http://purl.obolibrary.org/obo/GO_0016504 GO:2000340 biolink:BiologicalProcess positive regulation of chemokine (C-X-C motif) ligand 1 production Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. go-plus.json positive regulation of KC production|positive regulation of keratinocyte derived chemokine production|positive regulation of CXCL1 production|positive regulation of SCYB1 production http://purl.obolibrary.org/obo/GO_2000340 GO:0016505 biolink:MolecularActivity peptidase activator activity involved in apoptotic process Binds to and increases the activity of a peptidase that is involved in the apoptotic process. go-plus.json apoptotic protease activator activity http://purl.obolibrary.org/obo/GO_0016505 GO:2000341 biolink:BiologicalProcess regulation of chemokine (C-X-C motif) ligand 2 production Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. go-plus.json regulation of chemokine (C-C motif) ligand 2 secretion|regulation of MIP2 production|regulation of CCL2 secretion|chemokine (C-C motif) ligand 2 secretion|regulation of CXCL2 production|regulation of SCYB2 production|regulation of MIP-2 production http://purl.obolibrary.org/obo/GO_2000341 GO:0016506 biolink:MolecularActivity obsolete apoptosis activator activity OBSOLETE. The function held by products which directly activate any step in the process of apoptosis. go-plus.json apoptosis activator activity http://purl.obolibrary.org/obo/GO_0016506 GO:2000342 biolink:BiologicalProcess negative regulation of chemokine (C-X-C motif) ligand 2 production Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. go-plus.json negative regulation of CXCL2 production|negative regulation of MIP-2 production|negative regulation of SCYB2 production|negative regulation of MIP2 production|inhibition of CCL2 secretion|negative regulation of chemokine (C-C motif) ligand 2 secretion|inhibition of chemokine (C-C motif) ligand 2 secretion http://purl.obolibrary.org/obo/GO_2000342 GO:2000343 biolink:BiologicalProcess positive regulation of chemokine (C-X-C motif) ligand 2 production Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. go-plus.json positive regulation of CCL2 secretion|positive regulation of MIP2 production|positive regulation of CXCL2 production|positive regulation of MIP-2 production|positive regulation of SCYB2 production|positive regulation of chemokine (C-C motif) ligand 2 secretion http://purl.obolibrary.org/obo/GO_2000343 GO:0016500 biolink:MolecularActivity protein-hormone receptor activity Combining with a protein hormone to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016500 GO:2000344 biolink:BiologicalProcess positive regulation of acrosome reaction Any process that activates or increases the frequency, rate or extent of the acrosome reaction. go-plus.json http://purl.obolibrary.org/obo/GO_2000344 CHEBI:31697 biolink:ChemicalSubstance indolin-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_31697 chebi_ph7_3 GO:0016501 biolink:MolecularActivity prostacyclin receptor activity Combining with prostacyclin (PGI(2)) to initiate a change in cell activity. go-plus.json PGI receptor activity|PGI(2) receptor activity|prostaglandin I receptor activity http://purl.obolibrary.org/obo/GO_0016501 GO:2000345 biolink:BiologicalProcess regulation of hepatocyte proliferation Any process that modulates the frequency, rate or extent of hepatocyte proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000345 GO:0016502 biolink:MolecularActivity nucleotide receptor activity Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016502 CHEBI:16058 biolink:ChemicalSubstance 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16058 chebi_ph7_3 CHEBI:16057 biolink:ChemicalSubstance prenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16057 CHEBI:16054 biolink:ChemicalSubstance 2-benzylsuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16054 CHEBI:16055 biolink:ChemicalSubstance aldehydo-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16055 chebi_ph7_3 CHEBI:16052 biolink:ChemicalSubstance propene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16052 chebi_ph7_3 CHEBI:16053 biolink:ChemicalSubstance 1beta,3beta,4alpha-p-menthane-3,8-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16053 chebi_ph7_3 CHEBI:16050 biolink:ChemicalSubstance N-acetylisatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16050 chebi_ph7_3 CHEBI:16051 biolink:ChemicalSubstance poly(ribitol phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16051 GO:2000357 biolink:BiologicalProcess negative regulation of kidney smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000357 CHEBI:65003 biolink:ChemicalSubstance 2-deoxy-scyllo-inosamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65003 chebi_ph7_3 CHEBI:65004 biolink:ChemicalSubstance (-)-secoisolariciresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_65004 chebi_ph7_3 GO:2000358 biolink:BiologicalProcess positive regulation of kidney smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000358 GO:2000359 biolink:BiologicalProcess regulation of binding of sperm to zona pellucida Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida. go-plus.json regulation of ZPG binding http://purl.obolibrary.org/obo/GO_2000359 CHEBI:65006 biolink:ChemicalSubstance inositol phosphomannosylinositol phosphophytoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_65006 GO:0016518 biolink:MolecularActivity interleukin-14 receptor activity Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-14R|IL-14 receptor activity http://purl.obolibrary.org/obo/GO_0016518 GO:0016519 biolink:MolecularActivity gastric inhibitory peptide receptor activity Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein. go-plus.json GIP receptor activity|glucose-dependent insulinotropic polypeptide receptor activity http://purl.obolibrary.org/obo/GO_0016519 CHEBI:65000 biolink:ChemicalSubstance mannosylinositol phosphophytoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_65000 CHEBI:65001 biolink:ChemicalSubstance EC 3.1.1.3 (triacylglycerol lipase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_65001 CHEBI:65002 biolink:ChemicalSubstance 3-ammonio-2,3-dideoxy-scyllo-inosose(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65002 chebi_ph7_3 GO:0016514 biolink:CellularComponent SWI/SNF complex A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof. go-plus.json SWI-SNF complex http://purl.obolibrary.org/obo/GO_0016514 GO:2000350 biolink:BiologicalProcess positive regulation of CD40 signaling pathway Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway. go-plus.json positive regulation of CD40 signalling pathway http://purl.obolibrary.org/obo/GO_2000350 GO:0016515 biolink:MolecularActivity interleukin-13 receptor activity Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-13 receptor activity|IL-13R http://purl.obolibrary.org/obo/GO_0016515 GO:2000351 biolink:BiologicalProcess regulation of endothelial cell apoptotic process Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. go-plus.json regulation of programmed cell death of endothelial cells by apoptosis|regulation of apoptosis of endothelial cells|regulation of endothelial cell programmed cell death by apoptosis|regulation of programmed cell death, endothelial cells|regulation of endothelial cell apoptosis|regulation of killing of endothelial cells http://purl.obolibrary.org/obo/GO_2000351 GO:0016516 biolink:CellularComponent interleukin-4 receptor complex A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor. go-plus.json IL-4 receptor complex http://purl.obolibrary.org/obo/GO_0016516 GO:0016517 biolink:MolecularActivity interleukin-12 receptor activity Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-12 receptor activity|IL-12R http://purl.obolibrary.org/obo/GO_0016517 GO:2000352 biolink:BiologicalProcess negative regulation of endothelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. go-plus.json negative regulation of apoptosis of endothelial cells|negative regulation of programmed cell death, endothelial cells|negative regulation of endothelial cell apoptosis|negative regulation of programmed cell death of endothelial cells by apoptosis|negative regulation of killing of endothelial cells|negative regulation of endothelial cell programmed cell death by apoptosis http://purl.obolibrary.org/obo/GO_2000352 GO:2000353 biolink:BiologicalProcess positive regulation of endothelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. go-plus.json positive regulation of apoptosis of endothelial cells|positive regulation of programmed cell death of endothelial cells by apoptosis|positive regulation of programmed cell death, endothelial cells|positive regulation of endothelial cell apoptosis|positive regulation of endothelial cell programmed cell death by apoptosis|positive regulation of killing of endothelial cells http://purl.obolibrary.org/obo/GO_2000353 GO:0016510 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016510 GO:2000354 biolink:BiologicalProcess regulation of ovarian follicle development Any process that modulates the frequency, rate or extent of ovarian follicle development. go-plus.json regulation of follicular phase http://purl.obolibrary.org/obo/GO_2000354 CHEBI:65008 biolink:ChemicalSubstance 6'-oxoparomamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65008 GO:0016511 biolink:MolecularActivity obsolete endothelin-converting enzyme activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json endothelin-converting enzyme activity http://purl.obolibrary.org/obo/GO_0016511 GO:0016512 biolink:MolecularActivity obsolete endothelin-converting enzyme 1 activity OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor. go-plus.json ECE-1 activity|endothelin-converting enzyme 1 activity http://purl.obolibrary.org/obo/GO_0016512 CHEBI:16049 biolink:ChemicalSubstance CDP-abequose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16049 GO:2000355 biolink:BiologicalProcess negative regulation of ovarian follicle development Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. go-plus.json negative regulation of follicular phase http://purl.obolibrary.org/obo/GO_2000355 CHEBI:65009 biolink:ChemicalSubstance indol-3-ylmethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65009 GO:0016513 biolink:CellularComponent core-binding factor complex A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit. go-plus.json PEPB2 complex|CBF complex|AML1 complex http://purl.obolibrary.org/obo/GO_0016513 GO:2000356 biolink:BiologicalProcess regulation of kidney smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000356 CHEBI:16047 biolink:ChemicalSubstance Lys-tRNA(Lys) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16047 CHEBI:16048 biolink:ChemicalSubstance FMNH2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_16048 CHEBI:16046 biolink:ChemicalSubstance alpha-D-galactosyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16046 CHEBI:16044 biolink:ChemicalSubstance L-methionine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_16044 chebi_ph7_3 CHEBI:16042 biolink:ChemicalSubstance halide anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_16042 chebi_ph7_3 CHEBI:16083 biolink:ChemicalSubstance (S)-3-(indol-3-yl)-2-oxobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16083 CHEBI:16084 biolink:ChemicalSubstance beta-D-fructofuranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16084 CHEBI:16081 biolink:ChemicalSubstance dTDP-L-dihydrostreptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16081 CHEBI:16082 biolink:ChemicalSubstance UDP-alpha-D-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16082 NCBITaxon:4236 biolink:OrganismalEntity Lactuca sativa go-plus.json cultivated lettuce|garden lettuce http://purl.obolibrary.org/obo/NCBITaxon_4236 CHEBI:16080 biolink:ChemicalSubstance gamma-amino-beta-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16080 NCBITaxon:4235 biolink:OrganismalEntity Lactuca go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4235 GO:2000368 biolink:BiologicalProcess positive regulation of acrosomal vesicle exocytosis Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis. go-plus.json positive regulation of acrosome exocytosis|positive regulation of acrosomal granule exocytosis http://purl.obolibrary.org/obo/GO_2000368 GO:2000369 biolink:BiologicalProcess regulation of clathrin-dependent endocytosis Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis. go-plus.json regulation of clathrin-dependent endocytosis|regulation of clathrin coated pit-dependent endocytosis|regulation of clathrin-mediated endocytosis http://purl.obolibrary.org/obo/GO_2000369 CHEBI:65015 biolink:ChemicalSubstance paromamine(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65015 chebi_ph7_3 CHEBI:65016 biolink:ChemicalSubstance 6'-oxoparomamine(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65016 chebi_ph7_3 CHEBI:65010 biolink:ChemicalSubstance 2'-N-acetylparomamine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65010 chebi_ph7_3 CHEBI:65011 biolink:ChemicalSubstance nicotine blue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65011 CHEBI:65013 biolink:ChemicalSubstance extended quinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_65013 GO:2000360 biolink:BiologicalProcess negative regulation of binding of sperm to zona pellucida Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida. go-plus.json negative regulation of ZPG binding http://purl.obolibrary.org/obo/GO_2000360 GO:2000361 biolink:BiologicalProcess regulation of prostaglandin-E synthase activity Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity. go-plus.json regulation of Prostaglandin-H(2) E-isomerase activity|regulation of endoperoxide isomerase activity|regulation of prostaglandin endoperoxide E isomerase activity|regulation of prostaglandin H-E isomerase activity|regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|regulation of PGE2 isomerase activity|regulation of PGE isomerase activity|regulation of prostaglandin-H2 E-isomerase activity|regulation of PGH-PGE isomerase activity|regulation of prostaglandin R-prostaglandin E isomerase activity|regulation of prostaglandin endoperoxide E2 isomerase activity http://purl.obolibrary.org/obo/GO_2000361 GO:2000362 biolink:BiologicalProcess negative regulation of prostaglandin-E synthase activity Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity. go-plus.json negative regulation of prostaglandin-H2 E-isomerase activity|negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|negative regulation of PGE isomerase activity|negative regulation of prostaglandin R-prostaglandin E isomerase activity|negative regulation of PGH-PGE isomerase activity|negative regulation of endoperoxide isomerase activity|negative regulation of Prostaglandin-H(2) E-isomerase activity|negative regulation of prostaglandin endoperoxide E isomerase activity|negative regulation of prostaglandin endoperoxide E2 isomerase activity|negative regulation of PGE2 isomerase activity|negative regulation of prostaglandin H-E isomerase activity http://purl.obolibrary.org/obo/GO_2000362 GO:2000363 biolink:BiologicalProcess positive regulation of prostaglandin-E synthase activity Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity. go-plus.json positive regulation of prostaglandin H-E isomerase activity|positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|positive regulation of endoperoxide isomerase activity|positive regulation of Prostaglandin-H(2) E-isomerase activity|positive regulation of prostaglandin endoperoxide E isomerase activity|positive regulation of PGE isomerase activity|positive regulation of PGH-PGE isomerase activity|positive regulation of prostaglandin R-prostaglandin E isomerase activity|positive regulation of PGE2 isomerase activity|positive regulation of prostaglandin endoperoxide E2 isomerase activity|positive regulation of prostaglandin-H2 E-isomerase activity http://purl.obolibrary.org/obo/GO_2000363 CHEBI:65018 biolink:ChemicalSubstance 2'-N-acetylparomamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65018 GO:2000364 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000364 GO:2000365 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000365 GO:2000366 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000366 GO:2000367 biolink:BiologicalProcess regulation of acrosomal vesicle exocytosis Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis. go-plus.json regulation of acrosomal granule exocytosis|regulation of acrosome exocytosis http://purl.obolibrary.org/obo/GO_2000367 CHEBI:16079 biolink:ChemicalSubstance benzyl 2-methyl-3-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16079 chebi_ph7_3 CHEBI:16076 biolink:ChemicalSubstance 11alpha-hydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16076 chebi_ph7_3 CHEBI:16077 biolink:ChemicalSubstance D-glucopyranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16077 CHEBI:16074 biolink:ChemicalSubstance 5beta-cholestan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16074 chebi_ph7_3 CHEBI:16072 biolink:ChemicalSubstance maleimide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16072 chebi_ph7_3 CHEBI:16073 biolink:ChemicalSubstance N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16073 CHEBI:16070 biolink:ChemicalSubstance 1,5-anhydro-D-glucitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16070 chebi_ph7_3 CHEBI:80657 biolink:ChemicalSubstance all-trans-18-hydroxyretinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80657 CHEBI:80658 biolink:ChemicalSubstance 5,6-epoxyretinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80658 GO:2000379 biolink:BiologicalProcess positive regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process. go-plus.json positive regulation of reactive oxygen species metabolism|positive regulation of ROS metabolic process http://purl.obolibrary.org/obo/GO_2000379 CHEBI:80656 biolink:ChemicalSubstance all-trans-4-oxoretinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80656 CHEBI:65027 biolink:ChemicalSubstance 3-amino-2,3-dideoxy-scyllo-inosose go-plus.json http://purl.obolibrary.org/obo/CHEBI_65027 CHEBI:65028 biolink:ChemicalSubstance ribostamycin(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65028 chebi_ph7_3 CHEBI:80651 biolink:ChemicalSubstance 1,2-ditetradecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_80651 chebi_ph7_3 CHEBI:65023 biolink:ChemicalSubstance anti-asthmatic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_65023 GO:2000371 biolink:BiologicalProcess regulation of DNA topoisomerase (ATP-hydrolyzing) activity Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. go-plus.json regulation of DNA topoisomerase II|regulation of topoisomerase II|regulation of topoisomerase|regulation of DNA topoisomerase IV activity|regulation of DNA topoisomerase type II activity|regulation of type II DNA topoisomerase activity|regulation of deoxyribonucleic topoisomerase activity|regulation of deoxyribonucleate topoisomerase|regulation of DNA topoisomerase (ATP-hydrolysing) http://purl.obolibrary.org/obo/GO_2000371 GO:2000372 biolink:BiologicalProcess negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. go-plus.json negative regulation of deoxyribonucleic topoisomerase activity|negative regulation of deoxyribonucleate topoisomerase|negative regulation of DNA topoisomerase (ATP-hydrolysing)|negative regulation of type II DNA topoisomerase activity|negative regulation of DNA topoisomerase type II activity|negative regulation of topoisomerase|negative regulation of DNA topoisomerase IV activity|negative regulation of DNA topoisomerase II|negative regulation of topoisomerase II http://purl.obolibrary.org/obo/GO_2000372 GO:2000373 biolink:BiologicalProcess positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. go-plus.json positive regulation of topoisomerase II|positive regulation of deoxyribonucleate topoisomerase|positive regulation of deoxyribonucleic topoisomerase activity|positive regulation of DNA topoisomerase (ATP-hydrolysing)|positive regulation of type II DNA topoisomerase activity|positive regulation of DNA topoisomerase type II activity|positive regulation of topoisomerase|positive regulation of DNA topoisomerase IV activity|positive regulation of DNA topoisomerase II http://purl.obolibrary.org/obo/GO_2000373 GO:2000374 biolink:BiologicalProcess regulation of oxygen metabolic process Any process that modulates the frequency, rate or extent of oxygen metabolic process. go-plus.json regulation of oxygen metabolism|regulation of diatomic oxygen metabolic process http://purl.obolibrary.org/obo/GO_2000374 GO:2000375 biolink:BiologicalProcess negative regulation of oxygen metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process. go-plus.json negative regulation of diatomic oxygen metabolic process|negative regulation of oxygen metabolism http://purl.obolibrary.org/obo/GO_2000375 CHEBI:65029 biolink:ChemicalSubstance trihydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_65029 GO:2000376 biolink:BiologicalProcess positive regulation of oxygen metabolic process Any process that activates or increases the frequency, rate or extent of oxygen metabolic process. go-plus.json positive regulation of diatomic oxygen metabolic process|positive regulation of oxygen metabolism http://purl.obolibrary.org/obo/GO_2000376 GO:2000377 biolink:BiologicalProcess regulation of reactive oxygen species metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process. go-plus.json regulation of reactive oxygen species metabolism|regulation of ROS metabolic process http://purl.obolibrary.org/obo/GO_2000377 GO:2000378 biolink:BiologicalProcess negative regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process. go-plus.json negative regulation of ROS metabolic process|negative regulation of reactive oxygen species metabolism http://purl.obolibrary.org/obo/GO_2000378 CHEBI:16069 biolink:ChemicalSubstance 1H-imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16069 chebi_ph7_3 CHEBI:16067 biolink:ChemicalSubstance 1D-myo-inositol 1,4,5,6-tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16067 CHEBI:16068 biolink:ChemicalSubstance 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16068 CHEBI:16065 biolink:ChemicalSubstance scopolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16065 chebi_ph7_3 CHEBI:16066 biolink:ChemicalSubstance 11-cis-retinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_16066 chebi_ph7_3 CHEBI:16063 biolink:ChemicalSubstance limonin 17-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16063 GO:2000370 biolink:BiologicalProcess positive regulation of clathrin-dependent endocytosis Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis. go-plus.json positive regulation of clathrin-dependent endocytosis|positive regulation of clathrin-mediated endocytosis|positive regulation of clathrin coated pit-dependent endocytosis http://purl.obolibrary.org/obo/GO_2000370 CHEBI:16064 biolink:ChemicalSubstance keto-3-deoxy-D-manno-octulosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16064 chebi_ph7_3 CHEBI:65030 biolink:ChemicalSubstance 2'''-acetyl-6'''-hydroxyneomycin C(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65030 chebi_ph7_3 CHEBI:65031 biolink:ChemicalSubstance 6'''-hydroxyneomycin C(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65031 chebi_ph7_3 NCBITaxon:451871 biolink:OrganismalEntity Eurotiomycetidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_451871 GO:2000302 biolink:BiologicalProcess positive regulation of synaptic vesicle exocytosis Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_2000302 CHEBI:80666 biolink:ChemicalSubstance norbelladine go-plus.json http://purl.obolibrary.org/obo/CHEBI_80666 CHEBI:65036 biolink:ChemicalSubstance didehydroagroclavine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65036 chebi_ph7_3 GO:2000303 biolink:BiologicalProcess regulation of ceramide biosynthetic process Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process. go-plus.json regulation of ceramide synthesis|regulation of ceramide formation|regulation of ceramide biosynthesis|regulation of ceramide anabolism http://purl.obolibrary.org/obo/GO_2000303 CHEBI:65037 biolink:ChemicalSubstance miltiradiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_65037 chebi_ph7_3 CHEBI:80667 biolink:ChemicalSubstance 4'-O-methylnorbelladine go-plus.json http://purl.obolibrary.org/obo/CHEBI_80667 GO:2000304 biolink:BiologicalProcess positive regulation of ceramide biosynthetic process Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process. go-plus.json positive regulation of ceramide biosynthesis|positive regulation of ceramide anabolism|positive regulation of ceramide synthesis|positive regulation of ceramide formation http://purl.obolibrary.org/obo/GO_2000304 GO:2000305 biolink:BiologicalProcess semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance. go-plus.json semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon pathfinding|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon pathfinding http://purl.obolibrary.org/obo/GO_2000305 GO:2000306 biolink:BiologicalProcess positive regulation of photomorphogenesis Any process that activates or increases the frequency, rate or extent of photomorphogenesis. go-plus.json positive regulation of plant development in response to light http://purl.obolibrary.org/obo/GO_2000306 CHEBI:65032 biolink:ChemicalSubstance dihydrochanoclavine-I aldehyde(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65032 chebi_ph7_3 GO:2000307 biolink:BiologicalProcess regulation of tumor necrosis factor (ligand) superfamily member 11 production Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. go-plus.json regulation of TNFSF11 production|regulation of RANKL production http://purl.obolibrary.org/obo/GO_2000307 GO:2000308 biolink:BiologicalProcess negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. go-plus.json negative regulation of TNFSF11 production|negative regulation of RANKL production http://purl.obolibrary.org/obo/GO_2000308 CHEBI:65034 biolink:ChemicalSubstance 6,8-dimethyl-6,7-didehydroergolin-6-ium go-plus.json http://purl.obolibrary.org/obo/CHEBI_65034 chebi_ph7_3 CHEBI:65035 biolink:ChemicalSubstance festuclavine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65035 GO:2000309 biolink:BiologicalProcess positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. go-plus.json positive regulation of TNFSF11 production|positive regulation of RANKL production http://purl.obolibrary.org/obo/GO_2000309 CHEBI:16018 biolink:ChemicalSubstance acyl-[acyl-carrier protein] go-plus.json http://purl.obolibrary.org/obo/CHEBI_16018 CHEBI:16019 biolink:ChemicalSubstance prenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16019 chebi_ph7_3 GO:2000300 biolink:BiologicalProcess regulation of synaptic vesicle exocytosis Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_2000300 goslim_synapse CHEBI:16016 biolink:ChemicalSubstance dihydroxyacetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16016 chebi_ph7_3 GO:2000301 biolink:BiologicalProcess negative regulation of synaptic vesicle exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_2000301 CHEBI:16017 biolink:ChemicalSubstance benzyl thiocyanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16017 chebi_ph7_3 CHEBI:16015 biolink:ChemicalSubstance L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16015 CHEBI:16013 biolink:ChemicalSubstance 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16013 chebi_ph7_3 CHEBI:16010 biolink:ChemicalSubstance 5-oxoproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16010 CHEBI:16011 biolink:ChemicalSubstance 2-ethylhexan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16011 chebi_ph7_3 OBO:CP_0000040 biolink:OntologyClass reniform nucleus A concave nucleus shape where the indentation is smaller than half of the distance to the farthest nuclear margin. go-plus.json http://purl.obolibrary.org/obo/CP_0000040 CHEBI:65040 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-alpha-D-glucuronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65040 chebi_ph7_3 CHEBI:65041 biolink:ChemicalSubstance dihydrochanoclavine-I aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_65041 CHEBI:65042 biolink:ChemicalSubstance agroclavine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65042 chebi_ph7_3 NCBITaxon:451864 biolink:OrganismalEntity Dikarya go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_451864 OBO:CP_0000043 biolink:OntologyClass cartwheel heterochromatin Heterochromatin that is arranged in a carthwheel pattern. go-plus.json http://purl.obolibrary.org/obo/CP_0000043 GO:2000313 biolink:BiologicalProcess regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation. go-plus.json regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_2000313 CHEBI:65047 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-alpha-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65047 GO:2000314 biolink:BiologicalProcess negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation. go-plus.json negative regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_2000314 CHEBI:65048 biolink:ChemicalSubstance cyclo(tyrosyl-tyrosyl) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65048 chebi_ph7_3 GO:2000315 biolink:BiologicalProcess positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation. go-plus.json positive regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_2000315 GO:2000316 biolink:BiologicalProcess regulation of T-helper 17 type immune response Any process that modulates the frequency, rate or extent of T-helper 17 type immune response. go-plus.json regulation of Th17 immune response http://purl.obolibrary.org/obo/GO_2000316 GO:2000317 biolink:BiologicalProcess negative regulation of T-helper 17 type immune response Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response. go-plus.json negative regulation of Th17 immune response http://purl.obolibrary.org/obo/GO_2000317 CHEBI:65043 biolink:ChemicalSubstance 6'''-hydroxyneomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_65043 GO:2000318 biolink:BiologicalProcess positive regulation of T-helper 17 type immune response Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. go-plus.json positive regulation of Th17 immune response http://purl.obolibrary.org/obo/GO_2000318 CHEBI:65044 biolink:ChemicalSubstance 2'''-acetyl-6'''-hydroxyneomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_65044 NCBITaxon:451866 biolink:OrganismalEntity Taphrinomycotina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_451866 CHEBI:65045 biolink:ChemicalSubstance festuclavine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65045 chebi_ph7_3 GO:2000319 biolink:BiologicalProcess regulation of T-helper 17 cell differentiation Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation. go-plus.json regulation of T-helper 17 cell development http://purl.obolibrary.org/obo/GO_2000319 NCBITaxon:451868 biolink:OrganismalEntity Pleosporomycetidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_451868 CHEBI:65046 biolink:ChemicalSubstance 2-deoxy-scyllo-inosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_65046 CHEBI:16009 biolink:ChemicalSubstance 9-riburonosyladenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16009 CHEBI:16007 biolink:ChemicalSubstance methanethiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16007 chebi_ph7_3 GO:2000310 biolink:BiologicalProcess regulation of NMDA receptor activity Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity. go-plus.json regulation of N-methyl-D-aspartate selective glutamate receptor activity http://purl.obolibrary.org/obo/GO_2000310 CHEBI:16008 biolink:ChemicalSubstance salicylaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16008 chebi_ph7_3 GO:2000311 biolink:BiologicalProcess regulation of AMPA receptor activity Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity. go-plus.json regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity http://purl.obolibrary.org/obo/GO_2000311 CHEBI:16005 biolink:ChemicalSubstance methylarsonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16005 GO:2000312 biolink:BiologicalProcess regulation of kainate selective glutamate receptor activity Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_2000312 CHEBI:16003 biolink:ChemicalSubstance (R)-3-(4-hydroxyphenyl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16003 CHEBI:16004 biolink:ChemicalSubstance (R)-lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16004 chebi_ph7_3 CHEBI:16001 biolink:ChemicalSubstance 3-phospho-D-glyceroyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16001 CHEBI:16002 biolink:ChemicalSubstance D-glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16002 CHEBI:16000 biolink:ChemicalSubstance ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16000 CHEBI:16040 biolink:ChemicalSubstance cytosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16040 chebi_ph7_3 CHEBI:65052 biolink:ChemicalSubstance tetracosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65052 chebi_ph7_3 CHEBI:65053 biolink:ChemicalSubstance EC 4.1.1.19 (arginine decarboxylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_65053 GO:2000324 biolink:BiologicalProcess positive regulation of glucocorticoid receptor signaling pathway Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway. go-plus.json positive regulation of glucocorticoid receptor signalling pathway http://purl.obolibrary.org/obo/GO_2000324 GO:2000325 biolink:BiologicalProcess obsolete regulation of nuclear receptor coactivator activity OBSOLETE. Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. go-plus.json regulation of ligand-dependent nuclear receptor transcription co-activator activity|regulation of ligand-dependent nuclear receptor transcription coactivator activity|regulation of nuclear receptor transcription coactivator activity http://purl.obolibrary.org/obo/GO_2000325 CHEBI:65059 biolink:ChemicalSubstance docosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65059 chebi_ph7_3 GO:2000326 biolink:BiologicalProcess obsolete negative regulation of nuclear receptor transcription coactivator activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. go-plus.json negative regulation of ligand-dependent nuclear receptor transcription co-activator activity|negative regulation of ligand-dependent nuclear receptor transcription coactivator activity http://purl.obolibrary.org/obo/GO_2000326 GO:2000327 biolink:BiologicalProcess obsolete positive regulation of nuclear receptor transcription coactivator activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. go-plus.json positive regulation of ligand-dependent nuclear receptor transcription coactivator activity|positive regulation of ligand-dependent nuclear receptor transcription co-activator activity http://purl.obolibrary.org/obo/GO_2000327 GO:2000328 biolink:BiologicalProcess regulation of T-helper 17 cell lineage commitment Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment. go-plus.json regulation of T-helper 17 cell fate commitment|regulation of Th17 fate commitment|regulation of Th17 cell lineage commitment http://purl.obolibrary.org/obo/GO_2000328 GO:2000329 biolink:BiologicalProcess negative regulation of T-helper 17 cell lineage commitment Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment. go-plus.json negative regulation of T-helper 17 cell fate commitment|negative regulation of Th17 fate commitment|negative regulation of Th17 cell lineage commitment http://purl.obolibrary.org/obo/GO_2000329 CHEBI:65055 biolink:ChemicalSubstance 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65055 chebi_ph7_3 CHEBI:65056 biolink:ChemicalSubstance EC 3.1.3.11 (fructose-bisphosphatase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_65056 NCBITaxon:206351 biolink:OrganismalEntity Neisseriales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_206351 CHEBI:65057 biolink:ChemicalSubstance adenosine A1 receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_65057 GO:2000320 biolink:BiologicalProcess negative regulation of T-helper 17 cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. go-plus.json negative regulation of T-helper 17 cell development http://purl.obolibrary.org/obo/GO_2000320 GO:2000321 biolink:BiologicalProcess positive regulation of T-helper 17 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation. go-plus.json positive regulation of T-helper 17 cell development http://purl.obolibrary.org/obo/GO_2000321 GO:2000322 biolink:BiologicalProcess regulation of glucocorticoid receptor signaling pathway Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway. go-plus.json regulation of glucocorticoid receptor signalling pathway http://purl.obolibrary.org/obo/GO_2000322 CHEBI:16038 biolink:ChemicalSubstance phosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16038 GO:2000323 biolink:BiologicalProcess negative regulation of glucocorticoid receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway. go-plus.json negative regulation of glucocorticoid receptor signalling pathway http://purl.obolibrary.org/obo/GO_2000323 CHEBI:16039 biolink:ChemicalSubstance ITP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16039 OBO:CP_0000037 biolink:OntologyClass increased nucleus size A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. go-plus.json http://purl.obolibrary.org/obo/CP_0000037 CHEBI:16036 biolink:ChemicalSubstance ethyl (S)-3-hydroxyhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16036 chebi_ph7_3 CHEBI:16037 biolink:ChemicalSubstance 2-nitropropane go-plus.json http://purl.obolibrary.org/obo/CHEBI_16037 chebi_ph7_3 CHEBI:16034 biolink:ChemicalSubstance phosphoguanidinoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16034 OBO:CP_0000035 biolink:OntologyClass polychromatophilic cytoplasm Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions. go-plus.json http://purl.obolibrary.org/obo/CP_0000035 CHEBI:16035 biolink:ChemicalSubstance 2'-hydroxy-2,3-dihydrodaidzein go-plus.json http://purl.obolibrary.org/obo/CHEBI_16035 chebi_ph7_3 CHEBI:16032 biolink:ChemicalSubstance androsterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16032 chebi_ph7_3 CHEBI:16030 biolink:ChemicalSubstance acyldolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16030 chebi_ph7_3 OBO:CP_0000039 biolink:OntologyClass banded nucleus A concave nuclear shape where the nucleus is indented to more than half the distance to the farthest nuclear margin, but in no area is the chromatin condensed to a single filament. go-plus.json http://purl.obolibrary.org/obo/CP_0000039 CHEBI:16031 biolink:ChemicalSubstance indole-3-acetamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16031 chebi_ph7_3 CHEBI:65061 biolink:ChemicalSubstance 2,5-diketopiperazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_65061 chebi_ph7_3 CHEBI:65063 biolink:ChemicalSubstance cyclo(L-tyrosyl-L-tyrosyl) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65063 chebi_ph7_3 CHEBI:65064 biolink:ChemicalSubstance EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_65064 CHEBI:65060 biolink:ChemicalSubstance (9Z)-myristoleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65060 chebi_ph7_3 GO:2000335 biolink:BiologicalProcess regulation of endothelial microparticle formation Any process that modulates the frequency, rate or extent of endothelial microparticle formation. go-plus.json regulation of endothelial microparticle generation|regulation of endothelial microparticle release http://purl.obolibrary.org/obo/GO_2000335 CHEBI:65069 biolink:ChemicalSubstance 2-deoxystreptamine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65069 chebi_ph7_3 GO:2000336 biolink:BiologicalProcess negative regulation of endothelial microparticle formation Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation. go-plus.json negative regulation of endothelial microparticle release|negative regulation of endothelial microparticle generation http://purl.obolibrary.org/obo/GO_2000336 GO:2000337 biolink:BiologicalProcess positive regulation of endothelial microparticle formation Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation. go-plus.json positive regulation of endothelial microparticle release|positive regulation of endothelial microparticle generation http://purl.obolibrary.org/obo/GO_2000337 GO:2000338 biolink:BiologicalProcess regulation of chemokine (C-X-C motif) ligand 1 production Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. go-plus.json regulation of CXCL1 production|regulation of SCYB1 production|regulation of KC production|regulation of keratinocyte derived chemokine production http://purl.obolibrary.org/obo/GO_2000338 GO:2000339 biolink:BiologicalProcess negative regulation of chemokine (C-X-C motif) ligand 1 production Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. go-plus.json negative regulation of KC production|negative regulation of keratinocyte derived chemokine production|negative regulation of SCYB1 production|negative regulation of CXCL1 production http://purl.obolibrary.org/obo/GO_2000339 CHEBI:65065 biolink:ChemicalSubstance EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_65065 CHEBI:65066 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-arabinofuranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65066 chebi_ph7_3 CHEBI:65067 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65067 chebi_ph7_3 CHEBI:65068 biolink:ChemicalSubstance 6'''-oxoneomycin C(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65068 chebi_ph7_3 GO:2000330 biolink:BiologicalProcess positive regulation of T-helper 17 cell lineage commitment Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment. go-plus.json positive regulation of Th17 fate commitment|positive regulation of Th17 cell lineage commitment|positive regulation of T-helper 17 cell fate commitment http://purl.obolibrary.org/obo/GO_2000330 CHEBI:80690 biolink:ChemicalSubstance Thyroglobulin triiodothyronine go-plus.json http://purl.obolibrary.org/obo/CHEBI_80690 chebi_ph7_3 PR:000003237 biolink:Protein 14-3-3 protein A protein that is a stand alone version of the 14-3-3 protein (Pfam:PF00244) domain. go-plus.json http://purl.obolibrary.org/obo/PR_000003237 CHEBI:16029 biolink:ChemicalSubstance N(alpha),N(alpha)-dimethyl-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16029 GO:2000331 biolink:BiologicalProcess regulation of terminal button organization Any process that modulates the frequency, rate or extent of terminal button organization. go-plus.json regulation of terminal button organisation|regulation of terminal bouton organization|regulation of bouton organization|regulation of synaptic bouton organization|regulation of presynaptic bouton organization http://purl.obolibrary.org/obo/GO_2000331 GO:2000332 biolink:BiologicalProcess regulation of blood microparticle formation Any process that modulates the frequency, rate or extent of blood microparticle formation. go-plus.json regulation of microparticle release|regulation of microparticle generation http://purl.obolibrary.org/obo/GO_2000332 GO:2000333 biolink:BiologicalProcess negative regulation of blood microparticle formation Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation. go-plus.json negative regulation of microparticle release|negative regulation of microparticle generation http://purl.obolibrary.org/obo/GO_2000333 CHEBI:16027 biolink:ChemicalSubstance adenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16027 GO:2000334 biolink:BiologicalProcess positive regulation of blood microparticle formation Any process that activates or increases the frequency, rate or extent of blood microparticle formation. go-plus.json positive regulation of microparticle release|positive regulation of microparticle generation http://purl.obolibrary.org/obo/GO_2000334 CHEBI:16028 biolink:ChemicalSubstance L-2,4-diaminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16028 OBO:CP_0000027 biolink:OntologyClass acidophilic cytoplasm Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain. go-plus.json eosinophilic http://purl.obolibrary.org/obo/CP_0000027 CHEBI:16026 biolink:ChemicalSubstance LL-2,6-diaminopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16026 CHEBI:16023 biolink:ChemicalSubstance D-erythrulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16023 chebi_ph7_3 NCBITaxon:147554 biolink:OrganismalEntity Schizosaccharomycetes go-plus.json Archiascomycota http://purl.obolibrary.org/obo/NCBITaxon_147554 CHEBI:16024 biolink:ChemicalSubstance D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16024 CHEBI:16021 biolink:ChemicalSubstance oleandomycin 2'-O-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16021 CHEBI:16022 biolink:ChemicalSubstance CDP-ribitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16022 OBO:CP_0000028 biolink:OntologyClass basophilic cytoplasm Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions. go-plus.json http://purl.obolibrary.org/obo/CP_0000028 CHEBI:16020 biolink:ChemicalSubstance 1-methyladenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16020 chebi_ph7_3 NCBITaxon:147550 biolink:OrganismalEntity Sordariomycetes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147550 GO:0016587 biolink:CellularComponent Isw1 complex A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure. go-plus.json http://purl.obolibrary.org/obo/GO_0016587 GO:0016588 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016588 GO:0016589 biolink:CellularComponent NURF complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters. go-plus.json nucleosome remodeling factor complex http://purl.obolibrary.org/obo/GO_0016589 GO:0016583 biolink:BiologicalProcess obsolete nucleosome modeling OBSOLETE. (Was not defined before being made obsolete). go-plus.json nucleosome modeling http://purl.obolibrary.org/obo/GO_0016583 GO:0016584 biolink:BiologicalProcess nucleosome positioning Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. go-plus.json nucleosome spacing http://purl.obolibrary.org/obo/GO_0016584 NCBITaxon:147545 biolink:OrganismalEntity Eurotiomycetes go-plus.json bitunicate ascomycetes|Plectomycetes|Loculoascomycetes http://purl.obolibrary.org/obo/NCBITaxon_147545 GO:0016585 biolink:CellularComponent obsolete chromatin remodeling complex OBSOLETE. Any complex that mediates dynamic changes in eukaryotic chromatin. go-plus.json chromatin remodelling complex|chromatin remodeling complex|nucleosome remodeling complex http://purl.obolibrary.org/obo/GO_0016585 GO:0016586 biolink:CellularComponent RSC-type complex A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining. go-plus.json PBAF complex|Polybromo- and BAF containing complex|SWI/SNF complex B http://purl.obolibrary.org/obo/GO_0016586 NCBITaxon:147548 biolink:OrganismalEntity Leotiomycetes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147548 GO:0016580 biolink:CellularComponent Sin3 complex A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0016580 GO:0016581 biolink:CellularComponent NuRD complex An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. go-plus.json nucleosome remodeling and histone deacetylation complex|Mi-2 complex|NRD complex http://purl.obolibrary.org/obo/GO_0016581 GO:0016582 biolink:BiologicalProcess obsolete non-covalent chromatin modification OBSOLETE. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups. go-plus.json http://purl.obolibrary.org/obo/GO_0016582 OBO:CP_0000000 biolink:OntologyClass neutrophillic cytoplasm Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain. go-plus.json http://purl.obolibrary.org/obo/CP_0000000 NCBITaxon:147541 biolink:OrganismalEntity Dothideomycetes go-plus.json bitunicate ascomycetes|Loculoascomycetes http://purl.obolibrary.org/obo/NCBITaxon_147541 GO:0016598 biolink:BiologicalProcess protein arginylation The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway. go-plus.json protein amino acid arginylation http://purl.obolibrary.org/obo/GO_0016598 GO:0016599 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016599 GO:0016594 biolink:MolecularActivity glycine binding Binding to glycine, aminoethanoic acid. go-plus.json aminoethanoic acid binding|Gly binding|aminoacetic acid binding http://purl.obolibrary.org/obo/GO_0016594 GO:0016595 biolink:MolecularActivity glutamate binding Binding to glutamate, the anion of 2-aminopentanedioic acid. go-plus.json glutamic acid binding http://purl.obolibrary.org/obo/GO_0016595 GO:0016596 biolink:MolecularActivity thienylcyclohexylpiperidine binding Binding to thienylcyclohexylpiperidine. go-plus.json TCP binding http://purl.obolibrary.org/obo/GO_0016596 GO:0016597 biolink:MolecularActivity amino acid binding Binding to an amino acid, organic acids containing one or more amino substituents. go-plus.json http://purl.obolibrary.org/obo/GO_0016597 goslim_pir|goslim_metagenomics GO:0016590 biolink:CellularComponent ACF complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair. go-plus.json ATP-utilizing chromatin assembly and remodeling factor complex http://purl.obolibrary.org/obo/GO_0016590 NCBITaxon:147537 biolink:OrganismalEntity Saccharomycotina go-plus.json true yeasts http://purl.obolibrary.org/obo/NCBITaxon_147537 NCBITaxon:147538 biolink:OrganismalEntity Pezizomycotina go-plus.json Euascomycota http://purl.obolibrary.org/obo/NCBITaxon_147538 GO:0016591 biolink:CellularComponent RNA polymerase II, holoenzyme A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters. go-plus.json DNA-directed RNA polymerase II, holoenzyme http://purl.obolibrary.org/obo/GO_0016591 goslim_pir GO:0016592 biolink:CellularComponent mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. Wikipedia:Mediator_(coactivator) go-plus.json CDK8-containing TRAP/mediator complex|Srb-mediator complex|TRAP complex|L mediator complex http://purl.obolibrary.org/obo/GO_0016592 GO:0016593 biolink:CellularComponent Cdc73/Paf1 complex A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p. go-plus.json Paf1p complex|Paf1 complex http://purl.obolibrary.org/obo/GO_0016593 GO:0016569 biolink:BiologicalProcess obsolete covalent chromatin modification OBSOLETE. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. go-plus.json chromatin modification http://purl.obolibrary.org/obo/GO_0016569 GO:0016565 biolink:MolecularActivity obsolete general transcriptional repressor activity OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set. go-plus.json general transcriptional repressor activity http://purl.obolibrary.org/obo/GO_0016565 GO:0016566 biolink:MolecularActivity obsolete specific transcriptional repressor activity OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes. go-plus.json specific transcriptional repressor activity http://purl.obolibrary.org/obo/GO_0016566 GO:0016567 biolink:BiologicalProcess protein ubiquitination The process in which one or more ubiquitin groups are added to a protein. go-plus.json protein ubiquitylation|protein ubiquitinylation http://purl.obolibrary.org/obo/GO_0016567 GO:0016568 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016568 GO:0016561 biolink:BiologicalProcess protein import into peroxisome matrix, translocation The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation. go-plus.json protein translocation during protein import into peroxisome matrix|peroxisome receptor translocation|protein translocation during protein transport into peroxisome matrix|protein translocation during peroxisome matrix protein import|peroxisome matrix protein import, translocation|protein transport into peroxisome matrix, translocation http://purl.obolibrary.org/obo/GO_0016561 GO:0016562 biolink:BiologicalProcess protein import into peroxisome matrix, receptor recycling The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol. go-plus.json receptor recycling during protein transport into peroxisome matrix|receptor recycling during peroxisome matrix protein import|protein transport into peroxisome matrix, receptor recycling|receptor recycling during protein import into peroxisome matrix|PTS receptor recycling|peroxisome matrix protein import, receptor recycling|peroxisome receptor recycling http://purl.obolibrary.org/obo/GO_0016562 GO:0016563 biolink:MolecularActivity obsolete transcription activator activity OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription. go-plus.json transcription activator activity|transcriptional activator activity|transcription activating factor http://purl.obolibrary.org/obo/GO_0016563 GO:0016564 biolink:MolecularActivity obsolete transcription repressor activity OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription. go-plus.json transcription repressor activity|transcriptional repressor activity|negative transcriptional regulator activity http://purl.obolibrary.org/obo/GO_0016564 GO:0016560 biolink:BiologicalProcess protein import into peroxisome matrix, docking The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane. go-plus.json protein docking during peroxisome matrix protein import|peroxisome matrix protein import, docking|protein transport into peroxisome matrix, docking|protein docking during protein import into peroxisome matrix|protein docking during protein transport into peroxisome matrix|peroxisome receptor docking http://purl.obolibrary.org/obo/GO_0016560 GO:0016576 biolink:BiologicalProcess histone dephosphorylation The modification of histones by removal of phosphate groups. go-plus.json http://purl.obolibrary.org/obo/GO_0016576 GO:0016577 biolink:BiologicalProcess histone demethylation The modification of histones by removal of methyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0016577 GO:0016578 biolink:BiologicalProcess histone deubiquitination The modification of histones by removal of ubiquitin groups. go-plus.json histone deubiquitylation|histone deubiquitinylation http://purl.obolibrary.org/obo/GO_0016578 GO:0016579 biolink:BiologicalProcess protein deubiquitination The removal of one or more ubiquitin groups from a protein. go-plus.json protein deubiquitylation|protein deubiquitinylation|deubiquitination http://purl.obolibrary.org/obo/GO_0016579 GO:0016572 biolink:BiologicalProcess histone phosphorylation The modification of histones by addition of phosphate groups. go-plus.json http://purl.obolibrary.org/obo/GO_0016572 GO:0016573 biolink:BiologicalProcess histone acetylation The modification of a histone by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0016573 GO:0016574 biolink:BiologicalProcess histone ubiquitination The modification of histones by addition of ubiquitin groups. go-plus.json histone ubiquitylation|histone ubiquitinylation http://purl.obolibrary.org/obo/GO_0016574 GO:0016575 biolink:BiologicalProcess histone deacetylation The modification of histones by removal of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0016575 GO:0016570 biolink:BiologicalProcess histone modification The covalent alteration of one or more amino acid residues within a histone protein. Wikipedia:Histone#Histone_modifications_in_chromatin_regulation go-plus.json http://purl.obolibrary.org/obo/GO_0016570 goslim_yeast GO:0016571 biolink:BiologicalProcess histone methylation The modification of histones by addition of methyl groups. Wikipedia:Histone_methylation go-plus.json http://purl.obolibrary.org/obo/GO_0016571 GO:2000382 biolink:BiologicalProcess positive regulation of mesoderm development Any process that activates or increases the frequency, rate or extent of mesoderm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000382 GO:0016547 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016547 GO:0016548 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016548 GO:2000383 biolink:BiologicalProcess regulation of ectoderm development Any process that modulates the frequency, rate or extent of ectoderm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000383 GO:2000384 biolink:BiologicalProcess negative regulation of ectoderm development Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000384 GO:0016549 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016549 GO:2000385 biolink:BiologicalProcess positive regulation of ectoderm development Any process that activates or increases the frequency, rate or extent of ectoderm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000385 GO:0016543 biolink:BiologicalProcess male courtship behavior, orientation prior to leg tapping and wing vibration The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster. go-plus.json male courtship behaviour, orientation|male courtship behavior, orientation|male courtship behaviour, orientation prior to leg tapping and wing vibration http://purl.obolibrary.org/obo/GO_0016543 GO:2000386 biolink:BiologicalProcess positive regulation of ovarian follicle development Any process that activates or increases the frequency, rate or extent of ovarian follicle development. go-plus.json positive regulation of follicular phase http://purl.obolibrary.org/obo/GO_2000386 GO:0016544 biolink:BiologicalProcess male courtship behavior, tapping to detect pheromone The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster. go-plus.json male courtship behavior, tapping|male courtship behaviour, tapping to detect pheromone|male courtship behaviour, tapping http://purl.obolibrary.org/obo/GO_0016544 GO:2000387 biolink:BiologicalProcess regulation of antral ovarian follicle growth Any process that modulates the frequency, rate or extent of antral ovarian follicle growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000387 GO:0016545 biolink:BiologicalProcess male courtship behavior, veined wing vibration The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster. go-plus.json male courtship behavior, wing vibration|male courtship behaviour, veined wing vibration|male courtship behaviour, wing vibration http://purl.obolibrary.org/obo/GO_0016545 GO:2000388 biolink:BiologicalProcess positive regulation of antral ovarian follicle growth Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000388 GO:0016546 biolink:BiologicalProcess male courtship behavior, proboscis-mediated licking The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster. go-plus.json male courtship behaviour, proboscis-mediated licking|male courtship behavior, licking|male courtship behaviour, licking http://purl.obolibrary.org/obo/GO_0016546 GO:2000389 biolink:BiologicalProcess regulation of neutrophil extravasation Any process that modulates the frequency, rate or extent of neutrophil extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000389 GO:0016540 biolink:BiologicalProcess protein autoprocessing Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0016540 goslim_chembl GO:0016541 biolink:MolecularActivity obsolete intein OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity. go-plus.json intein http://purl.obolibrary.org/obo/GO_0016541 GO:0016542 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016542 CHEBI:16098 biolink:ChemicalSubstance 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16098 CHEBI:16099 biolink:ChemicalSubstance 4'-O-beta-D-glucosyl-cis-p-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16099 GO:2000380 biolink:BiologicalProcess regulation of mesoderm development Any process that modulates the frequency, rate or extent of mesoderm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000380 CHEBI:16096 biolink:ChemicalSubstance palmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16096 chebi_ph7_3 GO:2000381 biolink:BiologicalProcess negative regulation of mesoderm development Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. go-plus.json http://purl.obolibrary.org/obo/GO_2000381 CHEBI:16097 biolink:ChemicalSubstance GDP-6-deoxy-alpha-D-talose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16097 CHEBI:16094 biolink:ChemicalSubstance thiosulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16094 CHEBI:16095 biolink:ChemicalSubstance sepiapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16095 chebi_ph7_3 CHEBI:16092 biolink:ChemicalSubstance isoquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16092 chebi_ph7_3 CHEBI:16093 biolink:ChemicalSubstance 2-methylene-3-methylsuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16093 CHEBI:16091 biolink:ChemicalSubstance dolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16091 chebi_ph7_3 GO:2000393 biolink:BiologicalProcess negative regulation of lamellipodium morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis. go-plus.json negative regulation of lamellipodium organization http://purl.obolibrary.org/obo/GO_2000393 GO:0016558 biolink:BiologicalProcess protein import into peroxisome matrix The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix. go-plus.json protein transport to peroxisome matrix|peroxisome matrix protein import http://purl.obolibrary.org/obo/GO_0016558 GO:0016559 biolink:BiologicalProcess peroxisome fission The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments. go-plus.json peroxisome division|peroxisome proliferation http://purl.obolibrary.org/obo/GO_0016559 GO:2000394 biolink:BiologicalProcess positive regulation of lamellipodium morphogenesis Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis. go-plus.json positive regulation of lamellipodium organization http://purl.obolibrary.org/obo/GO_2000394 GO:2000395 biolink:BiologicalProcess regulation of ubiquitin-dependent endocytosis Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis. go-plus.json regulation of ubiquitin-mediated endocytosis http://purl.obolibrary.org/obo/GO_2000395 GO:2000396 biolink:BiologicalProcess negative regulation of ubiquitin-dependent endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis. go-plus.json negative regulation of ubiquitin-mediated endocytosis http://purl.obolibrary.org/obo/GO_2000396 GO:2000397 biolink:BiologicalProcess positive regulation of ubiquitin-dependent endocytosis Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis. go-plus.json positive regulation of ubiquitin-mediated endocytosis http://purl.obolibrary.org/obo/GO_2000397 GO:0016554 biolink:BiologicalProcess cytidine to uridine editing The conversion of a cytosine residue to uridine in an RNA molecule by deamination. go-plus.json http://purl.obolibrary.org/obo/GO_0016554 GO:2000398 biolink:BiologicalProcess regulation of thymocyte aggregation Any process that modulates the frequency, rate or extent of thymocyte aggregation. go-plus.json regulation of immature T cell aggregation|regulation of thymic lymphocyte aggregation|regulation of T cell precursor aggregation|regulation of immature T-lymphocyte aggregation|regulation of immature T-cell aggregation http://purl.obolibrary.org/obo/GO_2000398 GO:0016555 biolink:BiologicalProcess uridine to cytidine editing The conversion of a uridine residue to cytosine in an RNA molecule by amination. go-plus.json http://purl.obolibrary.org/obo/GO_0016555 GO:2000399 biolink:BiologicalProcess negative regulation of thymocyte aggregation Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation. go-plus.json negative regulation of immature T-lymphocyte aggregation|negative regulation of immature T-cell aggregation|negative regulation of T cell precursor aggregation|negative regulation of immature T cell aggregation|negative regulation of thymic lymphocyte aggregation http://purl.obolibrary.org/obo/GO_2000399 GO:0016556 biolink:BiologicalProcess mRNA modification The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. go-plus.json mRNA editing http://purl.obolibrary.org/obo/GO_0016556 GO:0016557 biolink:BiologicalProcess peroxisome membrane biogenesis The process in which a peroxisome membrane is synthesized, aggregates, and bonds together. go-plus.json http://purl.obolibrary.org/obo/GO_0016557 GO:0016550 biolink:BiologicalProcess obsolete insertion or deletion editing OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription. go-plus.json insertion or deletion editing|insertion/deletion editing http://purl.obolibrary.org/obo/GO_0016550 GO:0016551 biolink:BiologicalProcess obsolete posttranscriptional insertion or deletion editing OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription. go-plus.json posttranscriptional insertion or deletion editing|posttranscriptional insertion/deletion editing http://purl.obolibrary.org/obo/GO_0016551 GO:0016552 biolink:BiologicalProcess obsolete cotranscriptional insertion or deletion editing OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription. go-plus.json cotranscriptional insertion/deletion editing|cotranscriptional insertion or deletion editing http://purl.obolibrary.org/obo/GO_0016552 CHEBI:16089 biolink:ChemicalSubstance 6-deoxyerythronolide B go-plus.json http://purl.obolibrary.org/obo/CHEBI_16089 chebi_ph7_3 GO:0016553 biolink:BiologicalProcess base conversion or substitution editing Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s). go-plus.json base conversion/substitution editing http://purl.obolibrary.org/obo/GO_0016553 CHEBI:16087 biolink:ChemicalSubstance isocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16087 chebi_ph7_3 GO:2000390 biolink:BiologicalProcess negative regulation of neutrophil extravasation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000390 GO:2000391 biolink:BiologicalProcess positive regulation of neutrophil extravasation Any process that activates or increases the frequency, rate or extent of neutrophil extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_2000391 CHEBI:16085 biolink:ChemicalSubstance UDP-alpha-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16085 GO:2000392 biolink:BiologicalProcess regulation of lamellipodium morphogenesis Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis. go-plus.json regulation of lamellipodium organization http://purl.obolibrary.org/obo/GO_2000392 CHEBI:16086 biolink:ChemicalSubstance mycothione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16086 chebi_ph7_3 GO:0016529 biolink:CellularComponent sarcoplasmic reticulum A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage. Wikipedia:Endoplasmic_reticulum#Sarcoplasmic_reticulum go-plus.json http://purl.obolibrary.org/obo/GO_0016529 GO:0016525 biolink:BiologicalProcess negative regulation of angiogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. go-plus.json down-regulation of angiogenesis|downregulation of angiogenesis|down regulation of angiogenesis|inhibition of angiogenesis http://purl.obolibrary.org/obo/GO_0016525 GO:0016526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016526 GO:0016527 biolink:MolecularActivity obsolete brain-specific angiogenesis inhibitor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json brain-specific angiogenesis inhibitor activity http://purl.obolibrary.org/obo/GO_0016527 GO:0016528 biolink:CellularComponent sarcoplasm The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. Wikipedia:Sarcoplasm go-plus.json http://purl.obolibrary.org/obo/GO_0016528 GO:0016521 biolink:MolecularActivity pituitary adenylate cyclase activating polypeptide activity The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation. go-plus.json pituitary adenylyl cyclase activating polypeptide activity http://purl.obolibrary.org/obo/GO_0016521 GO:0016522 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016522 GO:0016523 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016523 GO:0016524 biolink:MolecularActivity latrotoxin receptor activity Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json latrophilin http://purl.obolibrary.org/obo/GO_0016524 GO:0016520 biolink:MolecularActivity growth hormone-releasing hormone receptor activity Combining with growth hormone-releasing hormone to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016520 GO:0016536 biolink:MolecularActivity obsolete cyclin-dependent protein kinase 5 activator regulator activity OBSOLETE. Modulation of the activity of cyclin-dependent protein kinase 5 activator. go-plus.json cyclin-dependent protein kinase 5 activator regulator activity|cyclin-dependent protein kinase 5 activator, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0016536 GO:0016537 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016537 GO:0016538 biolink:MolecularActivity cyclin-dependent protein serine/threonine kinase regulator activity Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. EC:2.7.1.-|Reactome:R-HSA-3215385 go-plus.json cyclin-dependent protein kinase regulator activity|cyclin|G1/S-specific cyclin|G2/M-specific cyclin|cyclin-dependent protein kinase, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0016538 GO:0016539 biolink:BiologicalProcess intein-mediated protein splicing The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues. go-plus.json intein http://purl.obolibrary.org/obo/GO_0016539 GO:0016532 biolink:MolecularActivity superoxide dismutase copper chaperone activity A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016532 GO:0016533 biolink:CellularComponent protein kinase 5 complex A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent. go-plus.json cyclin-dependent protein kinase 5 holoenzyme complex http://purl.obolibrary.org/obo/GO_0016533 GO:0016534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016534 GO:0016535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016535 GO:0016530 biolink:MolecularActivity metallochaperone activity Binding to and delivering metal ions to a target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0016530 goslim_pir GO:0016531 biolink:MolecularActivity copper chaperone activity Directly binding to and delivering copper ions to a target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0016531 GO:0075049 biolink:BiologicalProcess obsolete modulation of symbiont cell wall strengthening involved in entry into host OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of symbiont cell wall strengthening during entry into host http://purl.obolibrary.org/obo/GO_0075049 GO:0099016 biolink:BiologicalProcess DNA end degradation evasion by virus Any process, either active or passive, by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases. VZ:3963 go-plus.json http://purl.obolibrary.org/obo/GO_0099016 GO:0099017 biolink:BiologicalProcess maintenance of protein localization at cell tip Any process in which localization of a protein is maintained at the cell tip. go-plus.json maintenance of protein location at cell tip http://purl.obolibrary.org/obo/GO_0099017 GO:0099014 biolink:BiologicalProcess neuronal dense core vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0099014 GO:0099015 biolink:BiologicalProcess degradation of host chromosome by virus The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis. VZ:3947 go-plus.json http://purl.obolibrary.org/obo/GO_0099015 GO:0099012 biolink:CellularComponent neuronal dense core vesicle membrane The lipid bilayer surrounding a neuronal dense core vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0099012 goslim_synapse GO:0099013 biolink:CellularComponent neuronal dense core vesicle lumen The volume enclosed by a neuronal dense core vesicle membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099013 goslim_synapse GO:0099010 biolink:BiologicalProcess modification of postsynaptic structure Any process that modifies the structure of a postsynapse. go-plus.json synapse remodelling http://purl.obolibrary.org/obo/GO_0099010 goslim_synapse GO:0099011 biolink:BiologicalProcess neuronal dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels. go-plus.json http://purl.obolibrary.org/obo/GO_0099011 GO:1905250 biolink:BiologicalProcess obsolete positive regulation of memory OBSOLETE. Any process that activates or increases the frequency, rate or extent of memory. go-plus.json enhancement of memory http://purl.obolibrary.org/obo/GO_1905250 GO:1905251 biolink:BiologicalProcess epidermal growth factor receptor signaling pathway involved in heart process Any epidermal growth factor receptor signaling pathway that is involved in heart process. go-plus.json epidermal growth factor receptor signaling pathway involved in cardiac process|EGFR signaling pathway involved in cardiac process|EGF receptor signalling pathway involved in cardiac process|EGF receptor signaling pathway involved in heart process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|epidermal growth factor receptor signalling pathway involved in heart process|ERBB1 signaling pathway involved in cardiac process|EGFR signaling pathway involved in heart process|EGF receptor signalling pathway involved in heart process|EGF receptor signaling pathway involved in cardiac process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|epidermal growth factor receptor signalling pathway involved in cardiac process|ERBB1 signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1905251 GO:1905252 biolink:BiologicalProcess obsolete regulation of epidermal growth factor receptor signaling pathway involved in heart process OBSOLETE. Any regulation of epidermal growth factor receptor signaling pathway that is involved in heart process. go-plus.json regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in heart process|regulation of EGF receptor signalling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1905252 GO:1905253 biolink:BiologicalProcess obsolete negative regulation of epidermal growth factor receptor signaling pathway involved in heart process OBSOLETE. Any negative regulation of epidermal growth factor receptor signaling pathway that is involved in heart process. go-plus.json down regulation of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGFR signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signalling pathway involved in heart process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1905253 GO:1905254 biolink:BiologicalProcess obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process OBSOLETE. Any positive regulation of epidermal growth factor receptor signaling pathway that is involved in heart process. go-plus.json activation of epidermal growth factor receptor signaling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|stimulation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|activation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in cardiac process|stimulation of epidermal growth factor receptor signaling pathway involved in cardiac process http://purl.obolibrary.org/obo/GO_1905254 GO:1905255 biolink:BiologicalProcess regulation of RNA binding transcription factor activity Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity. go-plus.json regulation of transcription factor activity http://purl.obolibrary.org/obo/GO_1905255 GO:1905256 biolink:BiologicalProcess negative regulation of RNA binding transcription factor activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity. go-plus.json inhibition of RNA binding transcription factor activity|down regulation of RNA binding transcription factor activity|downregulation of RNA binding transcription factor activity|down-regulation of RNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_1905256 GO:1905246 biolink:BiologicalProcess negative regulation of aspartic-type peptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity. go-plus.json down-regulation of aspartic-type peptidase activity|downregulation of aspartic-type peptidase activity|down regulation of aspartic-type peptidase activity|inhibition of aspartic-type peptidase activity|pepsin inhibitor http://purl.obolibrary.org/obo/GO_1905246 GO:1905247 biolink:BiologicalProcess positive regulation of aspartic-type peptidase activity Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity. go-plus.json up regulation of aspartic-type peptidase activity|upregulation of aspartic-type peptidase activity|up-regulation of aspartic-type peptidase activity|activation of aspartic-type peptidase activity http://purl.obolibrary.org/obo/GO_1905247 GO:0090688 biolink:CellularComponent cleavage furrow rim The part of the cleavage furrow closest to the cell surface. go-plus.json http://purl.obolibrary.org/obo/GO_0090688 GO:1905248 biolink:BiologicalProcess obsolete regulation of memory OBSOLETE. Any process that modulates the frequency, rate or extent of memory. go-plus.json modulation of memory http://purl.obolibrary.org/obo/GO_1905248 GO:0090689 biolink:CellularComponent cleavage furrow leading edge The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring. go-plus.json http://purl.obolibrary.org/obo/GO_0090689 GO:1905249 biolink:BiologicalProcess obsolete negative regulation of memory OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of memory. go-plus.json inhibition of memory|suppression of memory http://purl.obolibrary.org/obo/GO_1905249 GO:0051070 biolink:BiologicalProcess galactomannan biosynthetic process The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units. go-plus.json galactomannan anabolism|galactomannan synthesis|galactomannan formation|galactomannan biosynthesis http://purl.obolibrary.org/obo/GO_0051070 GO:0051071 biolink:BiologicalProcess 4,6-pyruvylated galactose residue metabolic process The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain. go-plus.json PvGal metabolic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolism|4,6-pyruvylated galactose residue metabolism|PvGal metabolism http://purl.obolibrary.org/obo/GO_0051071 GO:0075040 biolink:BiologicalProcess regulation of establishment of turgor in appressorium Any process modulates the frequency, rate or extent of turgor formation in the symbiont appressorium. go-plus.json regulation of turgor formation in appressorium http://purl.obolibrary.org/obo/GO_0075040 GO:0090682 biolink:MolecularActivity GPCR bitter taste receptor activity A G protein-coupled receptor activity that is responsible for the sense of bitter taste. go-plus.json G protein-coupled receptor bitter taste receptor activity|G-protein coupled receptor bitter taste receptor activity http://purl.obolibrary.org/obo/GO_0090682 GO:0051074 biolink:MolecularActivity obsolete protein tetramerization activity OBSOLETE. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. go-plus.json protein tetramerization activity http://purl.obolibrary.org/obo/GO_0051074 GO:0075041 biolink:BiologicalProcess positive regulation of establishment of turgor in appressorium Any process that activates or increases the frequency, rate or extent of turgor formation in the symbiont appressorium. go-plus.json http://purl.obolibrary.org/obo/GO_0075041 GO:0090683 biolink:MolecularActivity GPCR sweet taste receptor activity A G protein-coupled receptor activity that is responsible for the sense of sweet taste. go-plus.json G-protein coupled receptor sweet taste receptor activity http://purl.obolibrary.org/obo/GO_0090683 GO:0075042 biolink:BiologicalProcess negative regulation of establishment of turgor in appressorium Any process that stops, prevents, or reduces the frequency, rate or extent of turgor formation in the symbiont appressorium. go-plus.json http://purl.obolibrary.org/obo/GO_0075042 GO:0051075 biolink:MolecularActivity S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA. RHEA:32155|EC:2.4.99.17 go-plus.json S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity http://purl.obolibrary.org/obo/GO_0051075 GO:0090680 biolink:BiologicalProcess disruption by virus of host outer membrane A process by which a virus has a negative effect on the functioning of a host outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090680 GO:0051072 biolink:BiologicalProcess 4,6-pyruvylated galactose residue biosynthetic process The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain. go-plus.json 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthetic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthesis|4,6-pyruvylated galactose residue anabolism|4,6-pyruvylated galactose residue synthesis|PvGal biosynthetic process|4,6-pyruvylated galactose residue biosynthesis|PvGal biosynthesis|4,6-pyruvylated galactose residue formation http://purl.obolibrary.org/obo/GO_0051072 GO:0075043 biolink:BiologicalProcess melanization of appressorium wall The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium. go-plus.json maintenance of turgor in appressorium by melanization|melanization of appressorium to maintain turgor pressure http://purl.obolibrary.org/obo/GO_0075043 GO:0090681 biolink:MolecularActivity GPCR taste receptor activity A G protein-coupled receptor activity that is responsible for the sense of taste. go-plus.json G-protein-coupled taste receptor activity|G-protein coupled taste receptor activity http://purl.obolibrary.org/obo/GO_0090681 GO:0075044 biolink:BiologicalProcess positive regulation by symbiont of host autophagy Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host autophagotic process|autophagy of host cells involved in interaction with symbiont|autophagy of host cells during interaction with symbiont http://purl.obolibrary.org/obo/GO_0075044 GO:0051073 biolink:MolecularActivity adenosylcobinamide-GDP ribazoletransferase activity Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin. EC:2.7.8.26|RHEA:16049|MetaCyc:COBALAMINSYN-RXN go-plus.json adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity|cobalamin synthase activity|cobalamin (5'-phosphate) synthase activity|CobS|cobalamin-5'-phosphate synthase activity http://purl.obolibrary.org/obo/GO_0051073 GO:0090686 biolink:MolecularActivity glycine betaine-activated nonselective monovalent cation channel activity Enables the transmembrane transfer of a monovalent cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0090686 GO:0051078 biolink:BiologicalProcess meiotic nuclear membrane disassembly The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs. go-plus.json meiotic nuclear envelope breakdown|meiotic nuclear envelope catabolism|meiotic nuclear envelope disassembly|meiotic nuclear envelope degradation http://purl.obolibrary.org/obo/GO_0051078 GO:0075045 biolink:BiologicalProcess regulation of formation by symbiont of haustorium for nutrient acquisition from host Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075045 GO:0051079 biolink:BiologicalProcess meiosis I nuclear membrane disassembly The controlled breakdown of the nuclear membranes during the first division of meiosis. go-plus.json meiosis I nuclear envelope disassembly|meiosis I nuclear envelope catabolism|meiosis I nuclear envelope degradation|meiosis I nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_0051079 GO:0090687 biolink:BiologicalProcess activation of meiosis I spindle assembly checkpoint Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_0090687 GO:0075046 biolink:BiologicalProcess positive regulation of formation by symbiont of haustorium for nutrient acquisition from host Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075046 GO:0075047 biolink:BiologicalProcess negative regulation of formation by symbiont of haustorium for nutrient acquisition from host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075047 GO:0099018 biolink:BiologicalProcess restriction-modification system evasion by virus Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction. VZ:3966 go-plus.json http://purl.obolibrary.org/obo/GO_0099018 GO:0090684 biolink:MolecularActivity contact chemoreceptor activity A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception. go-plus.json contact chemosensation receptor activity http://purl.obolibrary.org/obo/GO_0090684 GO:0051076 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051076 GO:0090685 biolink:BiologicalProcess RNA localization to nucleus A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. go-plus.json RNA localisation to nucleus http://purl.obolibrary.org/obo/GO_0090685 GO:0099019 biolink:BiologicalProcess maintenance of protein localization at growing cell tip Any process in which localization of a protein is maintained at the growing cell tip. go-plus.json maintenance of protein location at growing cell tip http://purl.obolibrary.org/obo/GO_0099019 GO:0051077 biolink:CellularComponent secondary cell septum Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum. go-plus.json secondary septum http://purl.obolibrary.org/obo/GO_0051077 GO:0075048 biolink:BiologicalProcess obsolete cell wall strengthening in symbiont involved in entry into host OBSOLETE. A process in which the cell wall of the symbiont is strengthened or thickened during penetration into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json cell wall thickening in symbiont during entry into host|cell wall strengthening in symbiont during entry into host|symbiont cell wall strengthening during entry into host http://purl.obolibrary.org/obo/GO_0075048 GO:0099027 biolink:CellularComponent anchored component of presynaptic endocytic zone membrane The component of the presynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099027 goslim_synapse GO:0075038 biolink:BiologicalProcess negative regulation of appressorium maturation Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium maturation. go-plus.json negative regulation of appressorium maturation on or near host|negative regulation of maturation of appressorium on or near host http://purl.obolibrary.org/obo/GO_0075038 GO:0075039 biolink:BiologicalProcess establishment of turgor in appressorium The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation of turgor in appressorium|establishment of turgor in symbiont appressorium on or near host|generation of turgor in appressorium http://purl.obolibrary.org/obo/GO_0075039 GO:0099028 biolink:CellularComponent anchored component of postynaptic endocytic zone membrane The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099028 goslim_synapse GO:0099025 biolink:CellularComponent anchored component of postsynaptic membrane The component of the postsynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099025 goslim_synapse GO:0099026 biolink:CellularComponent anchored component of presynaptic membrane The component of the presynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json anchored component of presynaptic plasma membrane http://purl.obolibrary.org/obo/GO_0099026 goslim_synapse GO:0099023 biolink:CellularComponent vesicle tethering complex Any protein complex that plays a role in vesicle tethering. go-plus.json http://purl.obolibrary.org/obo/GO_0099023 GO:0099024 biolink:BiologicalProcess plasma membrane invagination An infolding of the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099024 GO:0090690 biolink:CellularComponent obsolete heteroreceptor complex OBSOLETE. A receptor complex that consists of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger. The formation of the higher level complex initiates a change in cell function. go-plus.json http://purl.obolibrary.org/obo/GO_0090690 GO:0099021 biolink:CellularComponent cortical endoplasmic reticulum lumen The volume enclosed by the membranes of the cortical endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0099021 GO:0099022 biolink:BiologicalProcess vesicle tethering The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0099022 GO:1905260 biolink:BiologicalProcess positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. go-plus.json up regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|activation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up-regulation of nitrosative stress-induced apoptosis|positive regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|activation of nitrosative stress-induced intrinsic apoptotic signaling pathway|activation of nitrosative stress-induced apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|positive regulation of nitrosative stress-induced apoptosis|up regulation of nitrosative stress-induced apoptosis|positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|up regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|upregulation of nitrosative stress-induced apoptosis|upregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1905260 GO:0099020 biolink:CellularComponent perinuclear endoplasmic reticulum lumen The volume enclosed by the membranes of the perinuclear endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0099020 GO:1905261 biolink:BiologicalProcess regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. go-plus.json http://purl.obolibrary.org/obo/GO_1905261 GO:1905262 biolink:BiologicalProcess negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. go-plus.json downregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|inhibition of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination http://purl.obolibrary.org/obo/GO_1905262 GO:1905263 biolink:BiologicalProcess positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. go-plus.json upregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|up-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|activation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|up regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination http://purl.obolibrary.org/obo/GO_1905263 GO:1905264 biolink:BiologicalProcess blasticidin S metabolic process The chemical reactions and pathways involving blasticidin S. go-plus.json blasticidin S metabolism http://purl.obolibrary.org/obo/GO_1905264 GO:1905265 biolink:BiologicalProcess blasticidin S catabolic process The chemical reactions and pathways resulting in the breakdown of blasticidin S. go-plus.json blasticidin S breakdown|blasticidin S degradation|blasticidin S catabolism http://purl.obolibrary.org/obo/GO_1905265 GO:1905266 biolink:BiologicalProcess blasticidin S biosynthetic process The chemical reactions and pathways resulting in the formation of blasticidin S. go-plus.json blasticidin S anabolism|blasticidin S synthesis|blasticidin S formation|blasticidin S biosynthesis http://purl.obolibrary.org/obo/GO_1905266 GO:1905267 biolink:BiologicalProcess endonucleolytic cleavage involved in tRNA processing Any endonucleolytic RNA phosphodiester bond hydrolysis that is involved in tRNA processing. go-plus.json RNA phosphodiester bond hydrolysis, endonucleolytic involved in tRNA maturation http://purl.obolibrary.org/obo/GO_1905267 GO:1905257 biolink:BiologicalProcess positive regulation of RNA binding transcription factor activity Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity. go-plus.json up-regulation of RNA binding transcription factor activity|upregulation of RNA binding transcription factor activity|up regulation of RNA binding transcription factor activity|activation of RNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_1905257 GO:1905258 biolink:BiologicalProcess regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. go-plus.json regulation of nitrosative stress-induced apoptosis|regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress http://purl.obolibrary.org/obo/GO_1905258 GO:1905259 biolink:BiologicalProcess negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. go-plus.json negative regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|down-regulation of nitrosative stress-induced apoptosis|negative regulation of nitrosative stress-induced apoptosis|down-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to nitrosative stress|downregulation of nitrosative stress-induced apoptosis|downregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of nitrosative stress-induced apoptosis|down regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of nitrosative stress-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of nitrosative stress-induced apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress http://purl.obolibrary.org/obo/GO_1905259 GO:0090699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090699 GO:0051081 biolink:BiologicalProcess nuclear membrane disassembly The controlled breakdown of the nuclear membranes, for example during cellular division. go-plus.json nuclear envelope catabolism|nuclear envelope disassembly|nuclear envelope degradation|nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_0051081 GO:0051082 biolink:MolecularActivity unfolded protein binding Binding to an unfolded protein. Reactome:R-HSA-9694337|Reactome:R-HSA-9683772 go-plus.json chaperone activity http://purl.obolibrary.org/obo/GO_0051082 goslim_generic|goslim_chembl|goslim_yeast|goslim_drosophila GO:0051080 biolink:BiologicalProcess meiosis II nuclear membrane disassembly The controlled breakdown of the nuclear membranes during the second division of meiosis. go-plus.json meiosis II nuclear envelope catabolism|meiosis II nuclear envelope disassembly|meiosis II nuclear envelope degradation|meiosis II nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_0051080 GO:0051085 biolink:BiologicalProcess chaperone cofactor-dependent protein refolding The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release. go-plus.json chaperone cofactor-dependent 'de novo' protein folding|chaperone co-factor-dependent protein refolding|chaperone cofactor-dependent protein folding|chaperone co-factor-dependent protein folding|chaperone mediated protein folding requiring cofactor http://purl.obolibrary.org/obo/GO_0051085 GO:0075030 biolink:BiologicalProcess modulation of formation of symbiont germ tube hook structure for appressorium development Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation. go-plus.json modulation of symbiont germ tube hook structure formation on or near host|modulation of germ tube tip of symbiont on or near the exterior of host|regulation of formation of symbiont germ tube hook structure on or near host http://purl.obolibrary.org/obo/GO_0075030 GO:0090693 biolink:BiologicalProcess plant organ senescence The process that occurs in a plant organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0090693 GO:0075031 biolink:BiologicalProcess positive regulation of formation of symbiont germ tube hook structure for appressorium development Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation. go-plus.json positive regulation of germ tube tip of symbiont on or near the exterior of host|positive regulation of formation of symbiont germ tube hook structure on or near host|positive regulation of symbiont germ tube hook structure formation on or near host http://purl.obolibrary.org/obo/GO_0075031 GO:0051086 biolink:BiologicalProcess chaperone mediated protein folding independent of cofactor The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release. go-plus.json chaperone cofactor-independent protein folding http://purl.obolibrary.org/obo/GO_0051086 GO:0090694 biolink:CellularComponent Scc2-Scc4 cohesin loading complex A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA. go-plus.json Mis4-Ssl3 cohesin loading complex http://purl.obolibrary.org/obo/GO_0090694 GO:0075032 biolink:BiologicalProcess negative regulation of formation of symbiont germ tube hook structure for appressorium development Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation. go-plus.json negative regulation of symbiont germ tube hook structure formation on or near host|negative regulation of germ tube tip of symbiont on or near the exterior of host|negative regulation of formation of symbiont germ tube hook structure on or near host http://purl.obolibrary.org/obo/GO_0075032 GO:0090691 biolink:BiologicalProcess formation of plant organ boundary The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0090691 GO:0051083 biolink:BiologicalProcess 'de novo' cotranslational protein folding The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated. go-plus.json nascent polypeptide association|'de novo' co-translational protein folding|multidomain protein assembly http://purl.obolibrary.org/obo/GO_0051083 GO:0075033 biolink:BiologicalProcess obsolete appressorium septum formation OBSOLETE. The process in which a symbiont partition is formed to separate the appressorium from the germination tube, occurring during appressorium formation. go-plus.json septum formation involved in appressorium formation on or near host|septum formation involved in appressorium formation|septum formation during appressorium formation on or near host http://purl.obolibrary.org/obo/GO_0075033 GO:0051084 biolink:BiologicalProcess 'de novo' posttranslational protein folding The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis. go-plus.json 'de novo' post-translational protein folding http://purl.obolibrary.org/obo/GO_0051084 GO:0090692 biolink:CellularComponent mitochondrial membrane scission site The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission. go-plus.json http://purl.obolibrary.org/obo/GO_0090692 GO:0090697 biolink:BiologicalProcess post-embryonic plant organ morphogenesis Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json http://purl.obolibrary.org/obo/GO_0090697 GO:0075034 biolink:BiologicalProcess obsolete nuclear division involved in appressorium formation OBSOLETE. The process in which nuclear division occurs within a symbiont spore that contributes to appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json nuclear division during appressorium formation on or near host|nuclear division involved in appressorium formation on or near host http://purl.obolibrary.org/obo/GO_0075034 GO:0051089 biolink:BiologicalProcess constitutive protein ectodomain proteolysis The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands. go-plus.json http://purl.obolibrary.org/obo/GO_0051089 GO:0090698 biolink:BiologicalProcess post-embryonic plant morphogenesis The process, occurring after plant embryonic development, by which anatomical structures are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0090698 GO:0075035 biolink:BiologicalProcess appressorium maturation The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json appressorium maturation on or near host|maturation of appressorium on or near host|maturation of symbiont appressorium on or near host http://purl.obolibrary.org/obo/GO_0075035 GO:0075036 biolink:BiologicalProcess regulation of appressorium maturation Any process that modulates the frequency, rate or extent of symbiont appressorium maturation. go-plus.json regulation of appressorium maturation on or near host|regulation of maturation of appressorium on or near host http://purl.obolibrary.org/obo/GO_0075036 GO:0051087 biolink:MolecularActivity chaperone binding Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport. go-plus.json co-chaperone activity|co-chaperonin activity|chaperone protein binding http://purl.obolibrary.org/obo/GO_0051087 GO:0099029 biolink:CellularComponent anchored component of presynaptic active zone membrane The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099029 goslim_synapse GO:0090695 biolink:CellularComponent Wpl/Pds5 cohesin loading/unloading complex A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0090695 GO:0075037 biolink:BiologicalProcess positive regulation of appressorium maturation Any process that activates or increases the frequency, rate or extent of symbiont appressorium maturation. go-plus.json positive regulation of appressorium maturation on or near host|positive regulation maturation of appressorium on or near host http://purl.obolibrary.org/obo/GO_0075037 GO:0090696 biolink:BiologicalProcess post-embryonic plant organ development Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json http://purl.obolibrary.org/obo/GO_0090696 GO:0051088 biolink:BiologicalProcess obsolete PMA-inducible membrane protein ectodomain proteolysis OBSOLETE. The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist. go-plus.json http://purl.obolibrary.org/obo/GO_0051088 GO:1905270 biolink:BiologicalProcess Meynert cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell. go-plus.json http://purl.obolibrary.org/obo/GO_1905270 GO:1905271 biolink:BiologicalProcess regulation of proton-transporting ATP synthase activity, rotational mechanism Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism. go-plus.json regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|regulation of hydrogen ion translocating F-type ATPase activity|regulation of H+-transporting ATP synthase activity|regulation of hydrogen ion transporting two-sector ATPase activity http://purl.obolibrary.org/obo/GO_1905271 GO:1905272 biolink:BiologicalProcess negative regulation of proton-transporting ATP synthase activity, rotational mechanism Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism. go-plus.json down-regulation of proton-transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion transporting two-sector ATPase activity|negative regulation of hydrogen ion transporting two-sector ATPase activity|down regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down regulation of hydrogen ion translocating F-type ATPase activity|down regulation of H+-transporting ATP synthase activity|downregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of proton-transporting ATP synthase activity, rotational mechanism|downregulation of hydrogen ion translocating F-type ATPase activity|downregulation of hydrogen ion transporting two-sector ATPase activity|downregulation of H+-transporting ATP synthase activity|down regulation of hydrogen ion transporting two-sector ATPase activity|inhibition of hydrogen ion transporting two-sector ATPase activity|down-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|negative regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion translocating F-type ATPase activity|negative regulation of hydrogen ion translocating F-type ATPase activity|down-regulation of H+-transporting ATP synthase activity|down regulation of proton-transporting ATP synthase activity, rotational mechanism|negative regulation of H+-transporting ATP synthase activity|inhibition of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of hydrogen ion translocating F-type ATPase activity|downregulation of proton-transporting ATP synthase activity, rotational mechanism|inhibition of H+-transporting ATP synthase activity http://purl.obolibrary.org/obo/GO_1905272 GO:1905273 biolink:BiologicalProcess positive regulation of proton-transporting ATP synthase activity, rotational mechanism Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism. go-plus.json activation of hydrogen ion transporting two-sector ATPase activity|up-regulation of H+-transporting ATP synthase activity|up regulation of proton-transporting ATP synthase activity, rotational mechanism|activation of proton-transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion translocating F-type ATPase activity|upregulation of H+-transporting ATP synthase activity|positive regulation of hydrogen ion transporting two-sector ATPase activity|up regulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of proton-transporting ATP synthase activity, rotational mechanism|up regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up regulation of hydrogen ion translocating F-type ATPase activity|activation of hydrogen ion transporting ATP synthase activity, rotational mechanism|positive regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|activation of hydrogen ion translocating F-type ATPase activity|positive regulation of hydrogen ion translocating F-type ATPase activity|up regulation of H+-transporting ATP synthase activity|activation of H+-transporting ATP synthase activity|positive regulation of H+-transporting ATP synthase activity|upregulation of hydrogen ion transporting two-sector ATPase activity|upregulation of proton-transporting ATP synthase activity, rotational mechanism|up-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up-regulation of hydrogen ion translocating F-type ATPase activity|up-regulation of hydrogen ion transporting two-sector ATPase activity http://purl.obolibrary.org/obo/GO_1905273 GO:1905274 biolink:BiologicalProcess regulation of modification of postsynaptic actin cytoskeleton Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton. go-plus.json regulation of postsynaptic actin cytoskeleton remodelling http://purl.obolibrary.org/obo/GO_1905274 goslim_synapse GO:1905275 biolink:BiologicalProcess Rohon-Beard neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron. go-plus.json http://purl.obolibrary.org/obo/GO_1905275 GO:1905276 biolink:BiologicalProcess regulation of epithelial tube formation Any process that modulates the frequency, rate or extent of epithelial tube formation. go-plus.json http://purl.obolibrary.org/obo/GO_1905276 GO:1905277 biolink:BiologicalProcess negative regulation of epithelial tube formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. go-plus.json inhibition of epithelial tube formation|down regulation of epithelial tube formation|downregulation of epithelial tube formation|down-regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905277 GO:1905278 biolink:BiologicalProcess positive regulation of epithelial tube formation Any process that activates or increases the frequency, rate or extent of epithelial tube formation. go-plus.json up-regulation of epithelial tube formation|upregulation of epithelial tube formation|up regulation of epithelial tube formation|activation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905278 GO:1905268 biolink:BiologicalProcess negative regulation of chromatin organization Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. go-plus.json inhibition of establishment or maintenance of chromatin architecture|inhibition of chromatin organisation|downregulation of chromatin organization|negative regulation of chromatin modification|down regulation of chromatin organization|inhibition of chromatin organization|down-regulation of establishment or maintenance of chromatin architecture|negative regulation of establishment or maintenance of chromatin architecture|down-regulation of chromatin organisation|negative regulation of chromatin organisation|down-regulation of chromatin organization|downregulation of establishment or maintenance of chromatin architecture|downregulation of chromatin organisation|down regulation of establishment or maintenance of chromatin architecture|down regulation of chromatin organisation http://purl.obolibrary.org/obo/GO_1905268 GO:0090668 biolink:BiologicalProcess endothelial cell chemotaxis to vascular endothelial growth factor The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF). go-plus.json http://purl.obolibrary.org/obo/GO_0090668 GO:1905269 biolink:BiologicalProcess positive regulation of chromatin organization Any process that activates or increases the frequency, rate or extent of chromatin organization. go-plus.json up regulation of chromatin organization|upregulation of establishment or maintenance of chromatin architecture|upregulation of chromatin organisation|upregulation of chromatin organization|positive regulation of chromatin modification|activation of establishment or maintenance of chromatin architecture|up-regulation of establishment or maintenance of chromatin architecture|up-regulation of chromatin organisation|activation of chromatin organisation|activation of chromatin organization|up-regulation of chromatin organization|positive regulation of establishment or maintenance of chromatin architecture|positive regulation of chromatin organisation|up regulation of establishment or maintenance of chromatin architecture|up regulation of chromatin organisation http://purl.obolibrary.org/obo/GO_1905269 GO:0090669 biolink:BiologicalProcess telomerase RNA stabilization Prevention of degradation of telomerase RNA (TERC) molecules. go-plus.json TERC stabilization http://purl.obolibrary.org/obo/GO_0090669 GO:0090666 biolink:BiologicalProcess scaRNA localization to Cajal body A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body. go-plus.json http://purl.obolibrary.org/obo/GO_0090666 GO:0090667 biolink:BiologicalProcess cell chemotaxis to vascular endothelial growth factor The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF). go-plus.json http://purl.obolibrary.org/obo/GO_0090667 GO:0051092 biolink:BiologicalProcess positive regulation of NF-kappaB transcription factor activity Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. go-plus.json activation of NF-kappaB|NF-kappaB activation|activation of NF-kappaB transcription factor http://purl.obolibrary.org/obo/GO_0051092 GO:0051093 biolink:BiologicalProcess negative regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). go-plus.json inhibition of developmental process|down regulation of developmental process|downregulation of developmental process|down-regulation of developmental process http://purl.obolibrary.org/obo/GO_0051093 GO:0075060 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075060 GO:0051090 biolink:BiologicalProcess regulation of DNA-binding transcription factor activity Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. go-plus.json regulation of androgen receptor activity|regulation of thyroid hormone receptor activity|regulation of transcription factor activity|regulation of DNA binding transcription factor activity|regulation of sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0051090 GO:0075061 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075061 GO:0051091 biolink:BiologicalProcess positive regulation of DNA-binding transcription factor activity Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. go-plus.json up-regulation of transcription factor activity|upregulation of transcription factor activity|positive regulation of thyroid hormone receptor activity|up regulation of transcription factor activity|activation of transcription factor activity|positive regulation of transcription factor activity|stimulation of transcription factor activity|positive regulation of DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0051091 GO:0075062 biolink:BiologicalProcess obsolete regulation of invasive hypha growth OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont invasive hypha formation within host|regulation of symbiont invasive hypha formation in host http://purl.obolibrary.org/obo/GO_0075062 GO:0090660 biolink:BiologicalProcess cerebrospinal fluid circulation The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional. go-plus.json CSF circulation|CSF flow|cerebrospinal fluid flow http://purl.obolibrary.org/obo/GO_0090660 GO:0075063 biolink:BiologicalProcess obsolete positive regulation of invasive hypha growth OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont invasive hypha formation in host|positive regulation of symbiont invasive hypha formation within host http://purl.obolibrary.org/obo/GO_0075063 GO:0051096 biolink:BiologicalProcess positive regulation of helicase activity Any process that activates or increases the activity of a helicase. go-plus.json up regulation of helicase activity|activation of helicase activity|stimulation of helicase activity|up-regulation of helicase activity|upregulation of helicase activity http://purl.obolibrary.org/obo/GO_0051096 GO:0051097 biolink:BiologicalProcess negative regulation of helicase activity Any process that stops or reduces the activity of a helicase. go-plus.json down regulation of helicase activity|downregulation of helicase activity|down-regulation of helicase activity|inhibition of helicase activity http://purl.obolibrary.org/obo/GO_0051097 GO:0090661 biolink:CellularComponent box H/ACA telomerase RNP complex A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090661 GO:0075064 biolink:BiologicalProcess obsolete negative regulation invasive hypha growth OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont invasive hypha formation in host|negative regulation of symbiont invasive hypha formation within host http://purl.obolibrary.org/obo/GO_0075064 GO:0051094 biolink:BiologicalProcess positive regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). go-plus.json up-regulation of developmental process|upregulation of developmental process|up regulation of developmental process|activation of developmental process|stimulation of developmental process http://purl.obolibrary.org/obo/GO_0051094 GO:0075065 biolink:BiologicalProcess obsolete growth or development of symbiont in host cell OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont in host cell http://purl.obolibrary.org/obo/GO_0075065 GO:0051095 biolink:BiologicalProcess regulation of helicase activity Any process that modulates the frequency, rate or extent of helicase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0051095 GO:0075066 biolink:BiologicalProcess obsolete growth or development of symbiont in host organelle OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont in host organelle http://purl.obolibrary.org/obo/GO_0075066 GO:0090664 biolink:BiologicalProcess response to high population density Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area. go-plus.json response to crowding http://purl.obolibrary.org/obo/GO_0090664 GO:0075067 biolink:BiologicalProcess obsolete growth or development of symbiont in host intercellular space OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont in host intercellular space http://purl.obolibrary.org/obo/GO_0075067 GO:0090665 biolink:CellularComponent glycoprotein complex A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0090665 GO:0075068 biolink:BiologicalProcess obsolete growth or development of symbiont in host vascular tissue OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont in host vascular tissue http://purl.obolibrary.org/obo/GO_0075068 GO:0075069 biolink:BiologicalProcess adhesion of symbiont infection cushion to host The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont infection cushion to host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075069 GO:0051098 biolink:BiologicalProcess regulation of binding Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0051098 GO:0090662 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090662 GO:0090663 biolink:BiologicalProcess galanin-activated signaling pathway The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor. go-plus.json galanin signaling pathway|galanin-activated signalling pathway|galanin signalling pathway http://purl.obolibrary.org/obo/GO_0090663 GO:0051099 biolink:BiologicalProcess positive regulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. go-plus.json up regulation of binding|activation of binding|stimulation of binding|up-regulation of binding|upregulation of binding http://purl.obolibrary.org/obo/GO_0051099 GO:0099005 biolink:CellularComponent extrinsic component of postsynaptic recycling endosome membrane The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0099005 goslim_synapse GO:0099006 biolink:BiologicalProcess viral entry via permeabilization of endosomal membrane The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen. VZ:985 go-plus.json viral penetration via permeabilization of host membrane http://purl.obolibrary.org/obo/GO_0099006 GO:0099003 biolink:BiologicalProcess vesicle-mediated transport in synapse Any vesicle-mediated transport that occurs in a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099003 goslim_synapse GO:0099004 biolink:BiologicalProcess calmodulin dependent kinase signaling pathway Any signal transduction pathway involving calmodulin dependent kinase activity. go-plus.json CAMK signaling pathway http://purl.obolibrary.org/obo/GO_0099004 GO:0099001 biolink:BiologicalProcess viral genome ejection through host cell envelope, long flexible tail mechanism Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm. VZ:3952 go-plus.json viral long flexible tail ejection system http://purl.obolibrary.org/obo/GO_0099001 GO:0099002 biolink:BiologicalProcess viral genome ejection through host cell envelope, short tail mechanism Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. VZ:3954 go-plus.json viral short tail ejection system http://purl.obolibrary.org/obo/GO_0099002 GO:1905280 biolink:BiologicalProcess negative regulation of retrograde transport, endosome to Golgi Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi. go-plus.json inhibition of retrograde transport, endosome to Golgi|down-regulation of retrograde (endosome to Golgi) transport|negative regulation of retrograde (endosome to Golgi) transport|down regulation of retrograde transport, endosome to Golgi|downregulation of retrograde (endosome to Golgi) transport|downregulation of retrograde transport, endosome to Golgi|down regulation of retrograde (endosome to Golgi) transport|inhibition of retrograde (endosome to Golgi) transport|down-regulation of retrograde transport, endosome to Golgi http://purl.obolibrary.org/obo/GO_1905280 GO:0099000 biolink:BiologicalProcess viral genome ejection through host cell envelope, contractile tail mechanism Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope. VZ:3950 go-plus.json viral contractile tail ejection system http://purl.obolibrary.org/obo/GO_0099000 GO:1905281 biolink:BiologicalProcess positive regulation of retrograde transport, endosome to Golgi Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi. go-plus.json up-regulation of retrograde (endosome to Golgi) transport|activation of retrograde (endosome to Golgi) transport|up-regulation of retrograde transport, endosome to Golgi|upregulation of retrograde transport, endosome to Golgi|positive regulation of retrograde (endosome to Golgi) transport|up regulation of retrograde (endosome to Golgi) transport|up regulation of retrograde transport, endosome to Golgi|activation of retrograde transport, endosome to Golgi|upregulation of retrograde (endosome to Golgi) transport http://purl.obolibrary.org/obo/GO_1905281 GO:1905282 biolink:BiologicalProcess regulation of epidermal growth factor receptor signaling pathway involved in heart process Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process. go-plus.json regulation of EGF receptor signalling pathway involved in cardiac process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|regulation of epidermal growth factor receptor signalling pathway involved in heart process|regulation of EGFR signaling pathway involved in heart process|regulation of ERBB1 signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of ERBB1 signaling pathway involved in heart process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_1905282 GO:1905283 biolink:BiologicalProcess negative regulation of epidermal growth factor receptor signaling pathway involved in heart process Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process. go-plus.json inhibition of ERBB1 signaling pathway involved in cardiac process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down regulation of EGF receptor signaling pathway involved in heart process|inhibition of EGFR signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of EGF receptor signalling pathway involved in cardiac process|inhibition of EGF receptor signalling pathway involved in heart process|inhibition of EGF receptor signaling pathway involved in heart process|negative regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down-regulation of ERBB1 signaling pathway involved in heart process|negative regulation of ERBB1 signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signalling pathway involved in heart process|downregulation of EGFR signaling pathway involved in heart process|down regulation of ERBB1 signaling pathway involved in cardiac process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signalling pathway involved in heart process|down regulation of EGFR signaling pathway involved in heart process|inhibition of ERBB1 signaling pathway involved in heart process|downregulation of ERBB1 signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|down-regulation of EGF receptor signalling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|downregulation of EGF receptor signaling pathway involved in cardiac process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|inhibition of EGFR signaling pathway involved in heart process|down-regulation of EGFR signaling pathway involved in cardiac process|negative regulation of EGFR signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signalling pathway involved in cardiac process|down regulation of EGF receptor signalling pathway involved in heart process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down-regulation of epidermal growth factor receptor signalling pathway involved in heart process|downregulation of EGF receptor signalling pathway involved in heart process|negative regulation of epidermal growth factor receptor signalling pathway involved in heart process|down-regulation of ERBB1 signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process|negative regulation of ERBB1 signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down regulation of ERBB1 signaling pathway involved in heart process|downregulation of EGFR signaling pathway involved in cardiac process|inhibition of EGF receptor signaling pathway involved in cardiac process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|inhibition of EGF receptor signalling pathway involved in cardiac process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signalling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of ERBB1 signaling pathway involved in heart process|down regulation of EGFR signaling pathway involved in cardiac process|down-regulation of EGF receptor signalling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in heart process|downregulation of EGF receptor signaling pathway involved in heart process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process|down-regulation of EGFR signaling pathway involved in heart process|down regulation of EGF receptor signalling pathway involved in cardiac process http://purl.obolibrary.org/obo/GO_1905283 GO:1905284 biolink:BiologicalProcess positive regulation of epidermal growth factor receptor signaling pathway involved in heart process Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process. go-plus.json activation of ERBB1 signaling pathway involved in heart process|positive regulation of ERBB1 signaling pathway involved in heart process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signalling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of EGF receptor signalling pathway involved in heart process|upregulation of ERBB1 signaling pathway involved in cardiac process|upregulation of EGF receptor signaling pathway involved in heart process|up regulation of EGFR signaling pathway involved in heart process|up regulation of EGF receptor signalling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of EGFR signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in cardiac process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up regulation of EGF receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up-regulation of ERBB1 signaling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|activation of EGF receptor signalling pathway involved in cardiac process|upregulation of EGF receptor signalling pathway involved in heart process|activation of EGFR signaling pathway involved in cardiac process|up-regulation of EGF receptor signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of ERBB1 signaling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signalling pathway involved in heart process|activation of epidermal growth factor receptor signalling pathway involved in heart process|upregulation of EGFR signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signalling pathway involved in heart process|positive regulation of ERBB1 signaling pathway involved in cardiac process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in cardiac process|up-regulation of EGF receptor signalling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|upregulation of EGF receptor signaling pathway involved in cardiac process|up regulation of EGFR signaling pathway involved in cardiac process|upregulation of ERBB1 signaling pathway involved in heart process|activation of ERBB1 signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of EGF receptor signalling pathway involved in heart process|activation of EGFR signaling pathway involved in heart process|activation of EGF receptor signalling pathway involved in heart process|up-regulation of EGFR signaling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in heart process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in heart process|up-regulation of ERBB1 signaling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of EGF receptor signaling pathway involved in heart process|upregulation of EGF receptor signalling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up-regulation of EGF receptor signaling pathway involved in cardiac process|upregulation of EGFR signaling pathway involved in cardiac process|up regulation of ERBB1 signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signalling pathway involved in cardiac process http://purl.obolibrary.org/obo/GO_1905284 GO:1905285 biolink:BiologicalProcess fibrous ring of heart morphogenesis The developmental process by which a fibrous ring of heart is generated and organized. go-plus.json coronary tendon morphogenesis|Lower's ring morphogenesis|aortic annulus morphogenesis|atrioventricular ring morphogenesis|anulus fibrosus cordis morphogenesis|anulus fibrosus of heart morphogenesis|annulus fibrosus cordis morphogenesis http://purl.obolibrary.org/obo/GO_1905285 GO:1905286 biolink:CellularComponent serine-type peptidase complex A protein complex which is capable of serine-type peptidase activity. go-plus.json Factor VII - TF complex http://purl.obolibrary.org/obo/GO_1905286 GO:1905287 biolink:BiologicalProcess positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation. go-plus.json positive regulation of mitotic entry involved in cellular response to nitrogen starvation http://purl.obolibrary.org/obo/GO_1905287 GO:1905288 biolink:BiologicalProcess vascular associated smooth muscle cell apoptotic process Any apoptotic process in a vascular associated smooth muscle cell. go-plus.json vascular smooth muscle cell apoptosis|vascular associated smooth muscle cell apoptosis|vascular smooth muscle cell apoptotic process|VSMC apoptosis|VSMC apoptotic process http://purl.obolibrary.org/obo/GO_1905288 GO:1905289 biolink:BiologicalProcess regulation of CAMKK-AMPK signaling cascade Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade. go-plus.json regulation of stress-activated AMP-activated protein kinase signaling cascade http://purl.obolibrary.org/obo/GO_1905289 GO:0090679 biolink:BiologicalProcess cell differentiation involved in phenotypic switching A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. go-plus.json http://purl.obolibrary.org/obo/GO_0090679 GO:1905279 biolink:BiologicalProcess regulation of retrograde transport, endosome to Golgi Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi. go-plus.json regulation of retrograde (endosome to Golgi) transport http://purl.obolibrary.org/obo/GO_1905279 GO:0090677 biolink:BiologicalProcess reversible differentiation A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another. go-plus.json http://purl.obolibrary.org/obo/GO_0090677 GO:0090678 biolink:BiologicalProcess cell dedifferentiation involved in phenotypic switching A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. go-plus.json http://purl.obolibrary.org/obo/GO_0090678 GO:0075050 biolink:BiologicalProcess obsolete positive regulation of symbiont cell wall strengthening involved in entry into host OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont cell wall strengthening during entry into host http://purl.obolibrary.org/obo/GO_0075050 GO:0075051 biolink:BiologicalProcess obsolete negative regulation of symbiont cell wall strengthening involved in entry into host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont cell wall strengthening during entry into host http://purl.obolibrary.org/obo/GO_0075051 GO:0090671 biolink:BiologicalProcess telomerase RNA localization to Cajal body A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body. go-plus.json http://purl.obolibrary.org/obo/GO_0090671 GO:0075052 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075052 GO:0090672 biolink:BiologicalProcess telomerase RNA localization Any process in which telomerase RNA is transported to, or maintained in, a specific location. go-plus.json http://purl.obolibrary.org/obo/GO_0090672 GO:0075053 biolink:BiologicalProcess penetration peg formation The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json symbiont penetration peg formation for entry into host|initiation of symbiont penetration peg|symbiont penetration peg initiation|formation of symbiont penetration peg for entry into host http://purl.obolibrary.org/obo/GO_0075053 GO:0075054 biolink:BiologicalProcess modulation of penetration peg formation Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of symbiont penetration peg formation for entry into host|modulation of symbiont penetration peg initiation http://purl.obolibrary.org/obo/GO_0075054 GO:0075055 biolink:BiologicalProcess positive regulation of penetration peg formation Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont penetration peg initiation|positive regulation of symbiont penetration peg formation for entry into host http://purl.obolibrary.org/obo/GO_0075055 GO:0090670 biolink:BiologicalProcess RNA localization to Cajal body A process in which an RNA is transported to, or maintained in, a Cajal body. go-plus.json http://purl.obolibrary.org/obo/GO_0090670 GO:0075056 biolink:BiologicalProcess obsolete negative regulation of penetration peg formation OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont penetration peg initiation|negative regulation of symbiont penetration peg formation for entry into host http://purl.obolibrary.org/obo/GO_0075056 GO:0090675 biolink:BiologicalProcess intermicrovillar adhesion The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin. go-plus.json http://purl.obolibrary.org/obo/GO_0090675 GO:0099009 biolink:BiologicalProcess viral genome circularization The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities. VZ:3968 go-plus.json http://purl.obolibrary.org/obo/GO_0099009 GO:0075057 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075057 GO:0090676 biolink:BiologicalProcess calcium ion transmembrane transport via low voltage-gated calcium channel A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel. go-plus.json generation of T-type calcium current http://purl.obolibrary.org/obo/GO_0090676 GO:0075058 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075058 GO:0090673 biolink:BiologicalProcess endothelial cell-matrix adhesion The binding of an endothelial cell to the extracellular matrix via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0090673 GO:0099007 biolink:CellularComponent extrinsic component of presynaptic endosome membrane The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0099007 goslim_synapse GO:0090674 biolink:BiologicalProcess endothelial cell-matrix adhesion via fibronectin The binding of an endothelial cell to the extracellular matrix via fibronectin. go-plus.json http://purl.obolibrary.org/obo/GO_0090674 GO:0075059 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075059 GO:0099008 biolink:BiologicalProcess viral entry via permeabilization of inner membrane The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane. VZ:985 go-plus.json viral penetration via permeabilization of host membrane http://purl.obolibrary.org/obo/GO_0099008 GO:0099058 biolink:CellularComponent integral component of postsynaptic endocytic zone membrane The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099058 goslim_synapse GO:0099059 biolink:CellularComponent integral component of presynaptic active zone membrane The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099059 goslim_synapse GO:0099056 biolink:CellularComponent integral component of presynaptic membrane The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral component of presynaptic plasma membrane http://purl.obolibrary.org/obo/GO_0099056 goslim_synapse GO:0099057 biolink:CellularComponent integral component of presynaptic endocytic zone membrane The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099057 goslim_synapse GO:1905290 biolink:BiologicalProcess negative regulation of CAMKK-AMPK signaling cascade Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade. go-plus.json down-regulation of stress-activated AMP-activated protein kinase signaling cascade|negative regulation of stress-activated AMP-activated protein kinase signaling cascade|downregulation of CAMKK-AMPK signaling cascade|down regulation of CAMKK-AMPK signaling cascade|inhibition of CAMKK-AMPK signaling cascade|inhibition of stress-activated AMP-activated protein kinase signaling cascade|down regulation of stress-activated AMP-activated protein kinase signaling cascade|downregulation of stress-activated AMP-activated protein kinase signaling cascade|down-regulation of CAMKK-AMPK signaling cascade http://purl.obolibrary.org/obo/GO_1905290 GO:0099054 biolink:BiologicalProcess presynapse assembly The aggregation, arrangement and bonding together of a set of components to form a presynapse. go-plus.json presynaptic terminal assembly|presynapse biogenesis http://purl.obolibrary.org/obo/GO_0099054 goslim_synapse GO:1905291 biolink:BiologicalProcess positive regulation of CAMKK-AMPK signaling cascade Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade. go-plus.json up regulation of CAMKK-AMPK signaling cascade|activation of stress-activated AMP-activated protein kinase signaling cascade|up-regulation of stress-activated AMP-activated protein kinase signaling cascade|upregulation of CAMKK-AMPK signaling cascade|upregulation of stress-activated AMP-activated protein kinase signaling cascade|up-regulation of CAMKK-AMPK signaling cascade|activation of CAMKK-AMPK signaling cascade|up regulation of stress-activated AMP-activated protein kinase signaling cascade|positive regulation of stress-activated AMP-activated protein kinase signaling cascade http://purl.obolibrary.org/obo/GO_1905291 GO:1905292 biolink:BiologicalProcess regulation of neural crest cell differentiation Any process that modulates the frequency, rate or extent of neural crest cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1905292 GO:0099055 biolink:CellularComponent integral component of postsynaptic membrane The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099055 goslim_synapse GO:0099052 biolink:BiologicalProcess vesicle scission involved in clathrin-mediated endocytosis The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099052 GO:1905293 biolink:BiologicalProcess negative regulation of neural crest cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. go-plus.json inhibition of neural crest cell differentiation|down regulation of neural crest cell differentiation|downregulation of neural crest cell differentiation|down-regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905293 GO:0099053 biolink:CellularComponent activating signal cointegrator 1 complex A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3. go-plus.json ASC-1 complex http://purl.obolibrary.org/obo/GO_0099053 GO:1905294 biolink:BiologicalProcess positive regulation of neural crest cell differentiation Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. go-plus.json up-regulation of neural crest cell differentiation|upregulation of neural crest cell differentiation|up regulation of neural crest cell differentiation|activation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905294 GO:1905295 biolink:BiologicalProcess regulation of neural crest cell fate specification Any process that modulates the frequency, rate or extent of neural crest cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_1905295 GO:0099050 biolink:BiologicalProcess vesicle scission The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099050 GO:0099051 biolink:BiologicalProcess vesicle scission involved in endocytosis The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099051 GO:1905296 biolink:BiologicalProcess negative regulation of neural crest cell fate specification Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification. go-plus.json down-regulation of neural crest cell fate specification|downregulation of neural crest cell fate specification|down regulation of neural crest cell fate specification|inhibition of neural crest cell fate specification http://purl.obolibrary.org/obo/GO_1905296 GO:1905297 biolink:BiologicalProcess positive regulation of neural crest cell fate specification Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification. go-plus.json upregulation of neural crest cell fate specification|up-regulation of neural crest cell fate specification|activation of neural crest cell fate specification|up regulation of neural crest cell fate specification http://purl.obolibrary.org/obo/GO_1905297 GO:1905298 biolink:BiologicalProcess regulation of intestinal epithelial cell development Any process that modulates the frequency, rate or extent of intestinal epithelial cell development. go-plus.json http://purl.obolibrary.org/obo/GO_1905298 GO:1905299 biolink:BiologicalProcess negative regulation of intestinal epithelial cell development Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development. go-plus.json down-regulation of intestinal epithelial cell development|downregulation of intestinal epithelial cell development|down regulation of intestinal epithelial cell development|inhibition of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_1905299 CHEBI:487869 biolink:ChemicalSubstance clavulanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_487869 chebi_ph7_3 GO:0075080 biolink:BiologicalProcess obsolete negative regulation by host of symbiont receptor-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075080 GO:0075081 biolink:BiologicalProcess obsolete modulation by host of symbiont transmembrane receptor-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075081 GO:0075082 biolink:BiologicalProcess obsolete positive regulation by host of symbiont transmembrane receptor-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075082 GO:0075083 biolink:BiologicalProcess obsolete negative regulation by host of symbiont transmembrane receptor-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075083 GO:0075084 biolink:BiologicalProcess obsolete modulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by host of symbiont transmembrane receptor-mediated cAMP signaling http://purl.obolibrary.org/obo/GO_0075084 GO:0075085 biolink:BiologicalProcess obsolete positive regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json promotion by host of symbiont transmembrane receptor protein activity involved in cAMP-mediated signal transduction|upregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|positive regulation by host of symbiont transmembrane receptor-mediated cAMP signaling|activation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|stimulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction http://purl.obolibrary.org/obo/GO_0075085 GO:0075086 biolink:BiologicalProcess obsolete negative regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json inhibition by host of symbiont transmembrane receptor-mediated cAMP signal transduction|downregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|negative regulation by host of symbiont transmembrane receptor-mediated cAMP signaling http://purl.obolibrary.org/obo/GO_0075086 GO:0075087 biolink:BiologicalProcess obsolete modulation by host of symbiont G protein-coupled receptor signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by host of symbiont G-protein coupled receptor protein signal transduction http://purl.obolibrary.org/obo/GO_0075087 GO:0075088 biolink:BiologicalProcess obsolete positive regulation by host of symbiont G protein-coupled receptor signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by host of symbiont G-protein coupled receptor protein signal transduction http://purl.obolibrary.org/obo/GO_0075088 GO:0075089 biolink:BiologicalProcess obsolete negative regulation by host of symbiont G protein-coupled receptor signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by host of symbiont G-protein coupled receptor protein signal transduction http://purl.obolibrary.org/obo/GO_0075089 CHEBI:5001 biolink:ChemicalSubstance fenofibrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_5001 chebi_ph7_3 GO:0099069 biolink:BiologicalProcess synaptic vesicle tethering involved in synaptic vesicle exocytosis The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0099069 GO:0099067 biolink:CellularComponent integral component of presynaptic endosome membrane The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099067 goslim_synapse GO:0099068 biolink:BiologicalProcess postsynapse assembly The aggregation, arrangement and bonding together of a set of components to form a postsynapse. go-plus.json postsynapse biogenesis http://purl.obolibrary.org/obo/GO_0099068 GO:0099065 biolink:CellularComponent integral component of spine apparatus membrane The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099065 goslim_synapse GO:0099066 biolink:CellularComponent integral component of neuronal dense core vesicle membrane The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099066 goslim_synapse GO:0099063 biolink:CellularComponent integral component of postsynaptic recycling endosome membrane The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099063 goslim_synapse GO:0099064 biolink:CellularComponent integral component of postsynaptic endosome membrane The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099064 goslim_synapse GO:0099061 biolink:CellularComponent integral component of postsynaptic density membrane The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099061 goslim_synapse GO:0099062 biolink:CellularComponent integral component of postsynaptic early endosome membrane The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099062 goslim_synapse GO:0099060 biolink:CellularComponent integral component of postsynaptic specialization membrane The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099060 goslim_synapse CHEBI:5019 biolink:ChemicalSubstance ferrichrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_5019 CHEBI:5017 biolink:ChemicalSubstance ferredoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_5017 GO:0075070 biolink:BiologicalProcess adhesion of symbiont hyphopodium to host The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont hyphopodium to host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075070 GO:0075071 biolink:BiologicalProcess modulation by symbiont of host autophagy Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json autophagy during symbiotic interaction|autophagy involved in symbiotic interaction|modulation by symbiont of host autophagic process http://purl.obolibrary.org/obo/GO_0075071 GO:0075072 biolink:BiologicalProcess obsolete autophagy of symbiont cells involved in interaction with host OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm during interaction with its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json autophagy of symbiont cells during interaction with host http://purl.obolibrary.org/obo/GO_0075072 GO:0075073 biolink:BiologicalProcess obsolete autophagy of symbiont cells on or near host surface OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm, occurring when the symbiont is on or near its host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075073 GO:0075074 biolink:BiologicalProcess obsolete spore autophagy involved in appressorium formation on or near host OBSOLETE. The process in which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json spore autophagy during appressorium formation on or near host|autophagy of spores during appressorium formation on or near host http://purl.obolibrary.org/obo/GO_0075074 GO:0075075 biolink:BiologicalProcess obsolete modulation by host of symbiont adenylate cyclase activity OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075075 GO:0075076 biolink:BiologicalProcess obsolete positive regulation by host of symbiont adenylate cyclase activity OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075076 GO:0075077 biolink:BiologicalProcess obsolete negative regulation by host of symbiont adenylate cyclase activity OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075077 GO:0075078 biolink:BiologicalProcess obsolete modulation by host of symbiont receptor-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075078 GO:0075079 biolink:BiologicalProcess obsolete positive regulation by host of symbiont receptor-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075079 GO:0099038 biolink:MolecularActivity ceramide floppase activity Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json ATP-dependent ceramide transporter activity|ATPase-coupled ceramide transporter activity|ceramide-translocating ATPase activity|ceramide floppase activity (cytosolic to exoplasmic leaftlet) http://purl.obolibrary.org/obo/GO_0099038 GO:0099039 biolink:BiologicalProcess sphingolipid translocation The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. go-plus.json http://purl.obolibrary.org/obo/GO_0099039 GO:0099036 biolink:CellularComponent anchored component of neuronal dense core vesicle membrane The component of the neuronal dense core vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099036 goslim_synapse GO:0099037 biolink:CellularComponent anchored component of presynaptic endosome membrane The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099037 goslim_synapse GO:0002089 biolink:BiologicalProcess lens morphogenesis in camera-type eye The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. go-plus.json lens morphogenesis|lens morphogenesis in camera-style eye http://purl.obolibrary.org/obo/GO_0002089 GO:0099034 biolink:CellularComponent anchored component of postsynaptic endosome membrane The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099034 goslim_synapse GO:0099035 biolink:CellularComponent anchored component of spine apparatus membrane The component of the spine apparatus membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099035 goslim_synapse GO:0099032 biolink:CellularComponent anchored component of postsynaptic early endosome membrane The component of the postsynaptic early endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099032 goslim_synapse GO:0099033 biolink:CellularComponent anchored component of postsynaptic recycling endosome membrane The component of the postsynaptic recycling endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099033 goslim_synapse GO:0002085 biolink:BiologicalProcess inhibition of neuroepithelial cell differentiation Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells. go-plus.json negative regulation of neural plate formation|repression of premature neural plate formation http://purl.obolibrary.org/obo/GO_0002085 GO:0099030 biolink:CellularComponent anchored component of postsynaptic specialization membrane The component of the postsynaptic specialization membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099030 goslim_synapse GO:0002086 biolink:BiologicalProcess diaphragm contraction A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0002086 GO:0099031 biolink:CellularComponent anchored component of postsynaptic density membrane The component of the postsynaptic density membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099031 goslim_synapse GO:0002087 biolink:BiologicalProcess regulation of respiratory gaseous exchange by nervous system process A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. go-plus.json regulation of respiratory gaseous exchange by neurological system process|neurological control of breathing http://purl.obolibrary.org/obo/GO_0002087 GO:0002088 biolink:BiologicalProcess lens development in camera-type eye The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. go-plus.json lens development|lens development in camera-style eye http://purl.obolibrary.org/obo/GO_0002088 GO:0002081 biolink:CellularComponent outer acrosomal membrane The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0002081 GO:0002082 biolink:BiologicalProcess regulation of oxidative phosphorylation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. go-plus.json OXPHOS http://purl.obolibrary.org/obo/GO_0002082 GO:0002083 biolink:MolecularActivity 4-hydroxybenzoate decaprenyltransferase activity Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate. Reactome:R-HSA-2162192|EC:2.5.1.39|MetaCyc:RXN-9230|RHEA:44564 go-plus.json http://purl.obolibrary.org/obo/GO_0002083 GO:0002084 biolink:BiologicalProcess protein depalmitoylation The removal of palymitoyl groups from a lipoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0002084 GO:0002090 biolink:BiologicalProcess regulation of receptor internalization Any process that modulates the frequency, rate or extent of receptor internalization. go-plus.json http://purl.obolibrary.org/obo/GO_0002090 GO:0002091 biolink:BiologicalProcess negative regulation of receptor internalization Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization. go-plus.json down-regulation of receptor internalization|downregulation of receptor internalization|down regulation of receptor internalization|inhibition of receptor internalization http://purl.obolibrary.org/obo/GO_0002091 GO:0099049 biolink:BiologicalProcess clathrin coat assembly involved in endocytosis The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation. go-plus.json http://purl.obolibrary.org/obo/GO_0099049 GO:0099047 biolink:BiologicalProcess clearance of foreign intracellular RNA A defense process that protects an organism from invading foreign RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0099047 GO:0099048 biolink:BiologicalProcess CRISPR-cas system An adaptive immune response of bacteria that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci. go-plus.json http://purl.obolibrary.org/obo/GO_0099048 GO:0099045 biolink:BiologicalProcess viral extrusion The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded. VZ:3951 go-plus.json http://purl.obolibrary.org/obo/GO_0099045 GO:0099046 biolink:BiologicalProcess clearance of foreign intracellular nucleic acids A defense process that protects an organism from DNA or RNA from an invading organism. go-plus.json http://purl.obolibrary.org/obo/GO_0099046 GO:0099043 biolink:BiologicalProcess cargo loading involved in clathrin-dependent endocytosis Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat. go-plus.json http://purl.obolibrary.org/obo/GO_0099043 GO:0099044 biolink:BiologicalProcess vesicle tethering to endoplasmic reticulum The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0099044 GO:0002096 biolink:CellularComponent polkadots A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals. go-plus.json http://purl.obolibrary.org/obo/GO_0002096 GO:0099041 biolink:BiologicalProcess vesicle tethering to Golgi The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0099041 GO:0002097 biolink:BiologicalProcess tRNA wobble base modification The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified. go-plus.json http://purl.obolibrary.org/obo/GO_0002097 GO:0099042 biolink:BiologicalProcess nucleation of clathrin-coated pit The first step in clathrin-dependent endocytosis: invagination of the plasma membrane to form a pit. go-plus.json http://purl.obolibrary.org/obo/GO_0099042 GO:0002098 biolink:BiologicalProcess tRNA wobble uridine modification The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. go-plus.json http://purl.obolibrary.org/obo/GO_0002098 GO:0099040 biolink:BiologicalProcess ceramide translocation The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet. go-plus.json http://purl.obolibrary.org/obo/GO_0099040 GO:0002099 biolink:BiologicalProcess tRNA wobble guanine modification The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified. go-plus.json http://purl.obolibrary.org/obo/GO_0002099 GO:0002092 biolink:BiologicalProcess positive regulation of receptor internalization Any process that activates or increases the frequency, rate or extent of receptor internalization. go-plus.json upregulation of receptor internalization|stimulation of receptor internalization|up-regulation of receptor internalization|activation of receptor internalization|up regulation of receptor internalization http://purl.obolibrary.org/obo/GO_0002092 GO:0002093 biolink:BiologicalProcess auditory receptor cell morphogenesis Any process that alters the size or shape of an auditory receptor cell. go-plus.json hair cell morphogenesis http://purl.obolibrary.org/obo/GO_0002093 GO:0002094 biolink:MolecularActivity polyprenyltransferase activity Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor). go-plus.json http://purl.obolibrary.org/obo/GO_0002094 GO:0002095 biolink:CellularComponent caveolar macromolecular signaling complex A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3). go-plus.json caveolar macromolecular signalling complex http://purl.obolibrary.org/obo/GO_0002095 GO:0075090 biolink:BiologicalProcess obsolete modulation by host of symbiont signal transduction mediated by G-protein alpha subunit OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075090 GO:0075091 biolink:BiologicalProcess obsolete positive regulation by host of symbiont signal transduction mediated by G-protein alpha subunit OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075091 GO:0075092 biolink:BiologicalProcess obsolete negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075092 GO:0075093 biolink:BiologicalProcess obsolete modulation by host of symbiont signal transduction mediated by G-protein beta subunit OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075093 GO:0075094 biolink:BiologicalProcess obsolete positive regulation by host of symbiont signal transduction mediated by G-protein beta subunit OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075094 GO:0075095 biolink:BiologicalProcess obsolete negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075095 GO:0075096 biolink:BiologicalProcess obsolete modulation by host of symbiont signal transduction mediated by G-protein gamma subunit OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075096 GO:0075097 biolink:BiologicalProcess obsolete positive regulation by host of symbiont signal transduction mediated by G-protein gamma subunit OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075097 GO:0075098 biolink:BiologicalProcess obsolete negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075098 GO:0075099 biolink:BiologicalProcess obsolete modulation by host of symbiont protein kinase-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075099 GO:0090602 biolink:BiologicalProcess sieve element enucleation The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0090602 GO:0090603 biolink:BiologicalProcess sieve element differentiation The process whereby a relatively unspecialized cell acquires specialized features of a sieve element. go-plus.json http://purl.obolibrary.org/obo/GO_0090603 GO:0090600 biolink:MolecularActivity alpha-1,3-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0090600 GO:0090601 biolink:BiologicalProcess enucleation The process in which nucleated precursor cells lose their nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0090601 GO:0090606 biolink:BiologicalProcess single-species surface biofilm formation A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface. go-plus.json multicellular pellicle formation http://purl.obolibrary.org/obo/GO_0090606 GO:0090607 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090607 GO:0090604 biolink:BiologicalProcess surface biofilm formation A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0090604 GO:0090605 biolink:BiologicalProcess submerged biofilm formation A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. go-plus.json solid substrate biofilm formation http://purl.obolibrary.org/obo/GO_0090605 GO:0051005 biolink:BiologicalProcess negative regulation of lipoprotein lipase activity Any process that stops or reduces the activity of the enzyme lipoprotein lipase. go-plus.json inhibition of lipoprotein lipase activity|down regulation of lipoprotein lipase activity|downregulation of lipoprotein lipase activity|down-regulation of lipoprotein lipase activity http://purl.obolibrary.org/obo/GO_0051005 GO:0051006 biolink:BiologicalProcess positive regulation of lipoprotein lipase activity Any process that activates or increases the activity of the enzyme lipoprotein lipase. go-plus.json up-regulation of lipoprotein lipase activity|upregulation of lipoprotein lipase activity|up regulation of lipoprotein lipase activity|activation of lipoprotein lipase activity|stimulation of lipoprotein lipase activity http://purl.obolibrary.org/obo/GO_0051006 GO:0051003 biolink:MolecularActivity ligase activity, forming nitrogen-metal bonds, forming coordination complexes Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex. EC:6.6.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0051003 GO:0051004 biolink:BiologicalProcess regulation of lipoprotein lipase activity Any process that modulates the activity of the enzyme lipoprotein lipase. go-plus.json http://purl.obolibrary.org/obo/GO_0051004 GO:0051009 biolink:MolecularActivity O-acetylhomoserine sulfhydrylase activity Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate. MetaCyc:ACETYLHOMOSER-CYS-RXN|RHEA:27822 go-plus.json http://purl.obolibrary.org/obo/GO_0051009 GO:0051007 biolink:MolecularActivity squalene-hopene cyclase activity Catalysis of the reaction: squalene = hop-22(29)-ene. RHEA:17637|MetaCyc:5.4.99.17-RXN|EC:5.4.99.17 go-plus.json squalene mutase (cyclizing)|squalene:hopene cyclase activity http://purl.obolibrary.org/obo/GO_0051007 GO:0051008 biolink:MolecularActivity Hsp27 protein binding Binding to Hsp27 proteins, a lightweight heat shock protein. go-plus.json http://purl.obolibrary.org/obo/GO_0051008 GO:0090608 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090608 GO:0090609 biolink:BiologicalProcess single-species submerged biofilm formation A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0090609 GO:0090613 biolink:MolecularActivity 5'-deoxyadenosine deaminase activity Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3. RHEA:42892|EC:3.5.4.41 go-plus.json http://purl.obolibrary.org/obo/GO_0090613 GO:0090614 biolink:MolecularActivity 5'-methylthioadenosine deaminase activity Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3. EC:3.5.4.31|RHEA:25025 go-plus.json http://purl.obolibrary.org/obo/GO_0090614 GO:0090611 biolink:BiologicalProcess ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_0090611 GO:0090612 biolink:MolecularActivity cAMP deaminase activity Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3. RHEA:22908|EC:3.5.4.46 go-plus.json cyclic adenosine monophosphate deaminase activity http://purl.obolibrary.org/obo/GO_0090612 GO:0090617 biolink:BiologicalProcess mitochondrial mRNA 5'-end processing Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome. go-plus.json http://purl.obolibrary.org/obo/GO_0090617 GO:0090618 biolink:BiologicalProcess DNA clamp unloading The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates. go-plus.json PCNA unloading http://purl.obolibrary.org/obo/GO_0090618 GO:0090615 biolink:BiologicalProcess mitochondrial mRNA processing Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0090615 GO:0090616 biolink:BiologicalProcess mitochondrial mRNA 3'-end processing Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome. go-plus.json http://purl.obolibrary.org/obo/GO_0090616 GO:0051001 biolink:BiologicalProcess negative regulation of nitric-oxide synthase activity Any process that stops or reduces the activity of the enzyme nitric-oxide synthase. go-plus.json down regulation of nitric-oxide synthase activity|inhibition of nitric-oxide synthase activity|NOS inhibitor|nitric-oxide synthase inhibitor|down-regulation of nitric-oxide synthase activity|negative regulation of NOS activity|downregulation of nitric-oxide synthase activity http://purl.obolibrary.org/obo/GO_0051001 GO:0090610 biolink:BiologicalProcess bundle sheath cell fate specification The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0090610 GO:0051002 biolink:MolecularActivity ligase activity, forming nitrogen-metal bonds Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.6.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0051002 GO:0051000 biolink:BiologicalProcess positive regulation of nitric-oxide synthase activity Any process that activates or increases the activity of the enzyme nitric-oxide synthase. go-plus.json upregulation of nitric-oxide synthase activity|stimulation of nitric-oxide synthase activity|NOS activator|nitric-oxide synthase activator|activation of nitric-oxide synthase activity|up-regulation of nitric-oxide synthase activity|positive regulation of NOS activity|up regulation of nitric-oxide synthase activity http://purl.obolibrary.org/obo/GO_0051000 GO:0051016 biolink:BiologicalProcess barbed-end actin filament capping The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. go-plus.json barbed-end F-actin capping activity|barbed-end actin capping activity|plus-end actin filament capping activity|plus-end F-actin capping activity http://purl.obolibrary.org/obo/GO_0051016 GO:0051017 biolink:BiologicalProcess actin filament bundle assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. go-plus.json actin bundling activity|actin cable formation|actin cable assembly http://purl.obolibrary.org/obo/GO_0051017 GO:0051014 biolink:BiologicalProcess actin filament severing The process in which an actin filament is broken down into smaller filaments. go-plus.json F-actin severing|barbed-end actin capping/severing activity|actin filament severing activity http://purl.obolibrary.org/obo/GO_0051014 GO:0051015 biolink:MolecularActivity actin filament binding Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. go-plus.json actin cross-linking activity|F-actin binding http://purl.obolibrary.org/obo/GO_0051015 GO:0051018 biolink:MolecularActivity protein kinase A binding Binding to a protein kinase A. go-plus.json protein kinase A anchoring activity|PKA binding http://purl.obolibrary.org/obo/GO_0051018 GO:0051019 biolink:MolecularActivity mitogen-activated protein kinase binding Binding to a mitogen-activated protein kinase. go-plus.json MAPK binding|MAP kinase binding|MAP-kinase anchoring activity http://purl.obolibrary.org/obo/GO_0051019 NCBITaxon:77658 biolink:OrganismalEntity Daphniidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_77658 GO:0051012 biolink:BiologicalProcess microtubule sliding The movement of one microtubule along another microtubule. go-plus.json microtubule translocation http://purl.obolibrary.org/obo/GO_0051012 GO:0051013 biolink:BiologicalProcess microtubule severing The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends. go-plus.json microtubule severing activity http://purl.obolibrary.org/obo/GO_0051013 GO:0051010 biolink:MolecularActivity microtubule plus-end binding Binding to the plus end of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0051010 GO:0051011 biolink:MolecularActivity microtubule minus-end binding Binding to the minus end of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0051011 GO:0051027 biolink:BiologicalProcess DNA transport The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051027 GO:0051028 biolink:BiologicalProcess mRNA transport The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051028 GO:0051025 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051025 GO:0051026 biolink:BiologicalProcess chiasma assembly The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids. go-plus.json http://purl.obolibrary.org/obo/GO_0051026 GO:0051029 biolink:BiologicalProcess rRNA transport The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051029 GO:1905200 biolink:BiologicalProcess gibberellic acid transmembrane transport The directed movement of gibberellic acid across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905200 GO:1905201 biolink:MolecularActivity gibberellin transmembrane transporter activity Enables the transfer of gibberellin from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1905201 GO:0051020 biolink:MolecularActivity GTPase binding Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP. go-plus.json http://purl.obolibrary.org/obo/GO_0051020 GO:0051023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051023 NCBITaxon:77643 biolink:OrganismalEntity Mycobacterium tuberculosis complex go-plus.json Mycobacterium complex http://purl.obolibrary.org/obo/NCBITaxon_77643 GO:0051024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051024 GO:0051021 biolink:MolecularActivity GDP-dissociation inhibitor binding Binding to a GDP-dissociation inhibitor protein. go-plus.json GDI binding http://purl.obolibrary.org/obo/GO_0051021 GO:0051022 biolink:MolecularActivity Rho GDP-dissociation inhibitor binding Binding to a Rho GDP-dissociation inhibitor protein. go-plus.json Rho GDI binding http://purl.obolibrary.org/obo/GO_0051022 GO:0051038 biolink:BiologicalProcess negative regulation of transcription involved in meiotic cell cycle Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle. go-plus.json downregulation of transcription during meiosis|down regulation of transcription during meiosis|inhibition of transcription during meiosis|down-regulation of transcription during meiosis|negative regulation of transcription, meiotic|negative regulation of meiotic transcription|meiotic repression of transcription http://purl.obolibrary.org/obo/GO_0051038 GO:0075005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075005 GO:0051039 biolink:BiologicalProcess positive regulation of transcription involved in meiotic cell cycle Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle. go-plus.json upregulation of transcription during meiosis|stimulation of transcription during meiosis|up-regulation of transcription during meiosis|activation of transcription during meiosis|positive regulation of meiotic transcription|up regulation of transcription during meiosis|positive regulation of transcription, meiotic http://purl.obolibrary.org/obo/GO_0051039 GO:0075006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075006 GO:0075007 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075007 GO:0051036 biolink:BiologicalProcess regulation of endosome size Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. go-plus.json endosome enlargement http://purl.obolibrary.org/obo/GO_0051036 GO:0051037 biolink:BiologicalProcess regulation of transcription involved in meiotic cell cycle Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle. go-plus.json regulation of transcription, meiotic|meiotic regulation of transcription http://purl.obolibrary.org/obo/GO_0051037 GO:0075008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075008 GO:0075009 biolink:BiologicalProcess germ tube formation Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json germ tube formation on or near host http://purl.obolibrary.org/obo/GO_0075009 GO:1905210 biolink:BiologicalProcess regulation of fibroblast chemotaxis Any process that modulates the frequency, rate or extent of fibroblast chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_1905210 GO:1905211 biolink:BiologicalProcess negative regulation of fibroblast chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis. go-plus.json down-regulation of fibroblast chemotaxis|inhibition of fibroblast chemotaxis|down regulation of fibroblast chemotaxis|downregulation of fibroblast chemotaxis http://purl.obolibrary.org/obo/GO_1905211 GO:1905212 biolink:BiologicalProcess positive regulation of fibroblast chemotaxis Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis. go-plus.json activation of fibroblast chemotaxis|up-regulation of fibroblast chemotaxis|upregulation of fibroblast chemotaxis|up regulation of fibroblast chemotaxis http://purl.obolibrary.org/obo/GO_1905212 GO:1905202 biolink:CellularComponent methylcrotonoyl-CoA carboxylase complex A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905202 GO:0090646 biolink:BiologicalProcess mitochondrial tRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0090646 GO:0090647 biolink:BiologicalProcess modulation of age-related behavioral decline Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory. go-plus.json http://purl.obolibrary.org/obo/GO_0090647 GO:1905203 biolink:BiologicalProcess regulation of connective tissue replacement Any process that modulates the frequency, rate or extent of connective tissue replacement. go-plus.json http://purl.obolibrary.org/obo/GO_1905203 GO:0090644 biolink:BiologicalProcess age-related resistance An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR). go-plus.json developmental resistance|ARR|mature seedling resistance|ontogenic resistance|senescence-induced resistance|flowering-induced resistance|adult seedling resistance http://purl.obolibrary.org/obo/GO_0090644 GO:1905204 biolink:BiologicalProcess negative regulation of connective tissue replacement Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement. go-plus.json down-regulation of connective tissue replacement|inhibition of connective tissue replacement|down regulation of connective tissue replacement|downregulation of connective tissue replacement http://purl.obolibrary.org/obo/GO_1905204 GO:1905205 biolink:BiologicalProcess positive regulation of connective tissue replacement Any process that activates or increases the frequency, rate or extent of connective tissue replacement. go-plus.json up regulation of connective tissue replacement|activation of connective tissue replacement|up-regulation of connective tissue replacement|upregulation of connective tissue replacement http://purl.obolibrary.org/obo/GO_1905205 GO:0090645 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090645 GO:1905206 biolink:BiologicalProcess positive regulation of hydrogen peroxide-induced cell death Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide. go-plus.json upregulation of cell death in response to H2O2|upregulation of hydrogen peroxide-mediated cell death|up-regulation of cell death in response to H2O2|activation of cell death in response to H2O2|up-regulation of cell death in response to hydrogen peroxide|positive regulation of cell death in response to hydrogen peroxide|up regulation of hydrogen peroxide-mediated cell death|upregulation of cell death in response to hydrogen peroxide|positive regulation of hydrogen peroxide-mediated cell death|positive regulation of cell death in response to H2O2|up regulation of cell death in response to H2O2|activation of hydrogen peroxide-mediated cell death|up regulation of cell death in response to hydrogen peroxide|up-regulation of hydrogen peroxide-mediated cell death|activation of cell death in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_1905206 GO:1905207 biolink:BiologicalProcess regulation of cardiocyte differentiation Any process that modulates the frequency, rate or extent of cardiocyte differentiation. go-plus.json regulation of cardiac cell differentiation|regulation of heart cell differentiation http://purl.obolibrary.org/obo/GO_1905207 GO:1905208 biolink:BiologicalProcess negative regulation of cardiocyte differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. go-plus.json down regulation of cardiocyte differentiation|down regulation of heart cell differentiation|inhibition of cardiocyte differentiation|inhibition of heart cell differentiation|negative regulation of cardiac cell differentiation|down-regulation of cardiac cell differentiation|downregulation of cardiac cell differentiation|down-regulation of cardiocyte differentiation|down-regulation of heart cell differentiation|negative regulation of heart cell differentiation|down regulation of cardiac cell differentiation|inhibition of cardiac cell differentiation|downregulation of cardiocyte differentiation|downregulation of heart cell differentiation http://purl.obolibrary.org/obo/GO_1905208 GO:0090648 biolink:BiologicalProcess response to environmental enrichment Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment. go-plus.json response to the introduction of novel objects http://purl.obolibrary.org/obo/GO_0090648 GO:0090649 biolink:BiologicalProcess response to oxygen-glucose deprivation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. go-plus.json response to OGD http://purl.obolibrary.org/obo/GO_0090649 GO:1905209 biolink:BiologicalProcess positive regulation of cardiocyte differentiation Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. go-plus.json up-regulation of cardiac cell differentiation|upregulation of cardiocyte differentiation|activation of cardiac cell differentiation|upregulation of heart cell differentiation|up-regulation of cardiocyte differentiation|activation of cardiocyte differentiation|up-regulation of heart cell differentiation|positive regulation of cardiac cell differentiation|activation of heart cell differentiation|up regulation of cardiac cell differentiation|positive regulation of heart cell differentiation|up regulation of cardiocyte differentiation|upregulation of cardiac cell differentiation|up regulation of heart cell differentiation http://purl.obolibrary.org/obo/GO_1905209 GO:0051030 biolink:BiologicalProcess snRNA transport The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051030 GO:0051031 biolink:BiologicalProcess tRNA transport The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051031 GO:0075000 biolink:BiologicalProcess response to host osmotic environment Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response of symbiont to host osmotic environment http://purl.obolibrary.org/obo/GO_0075000 GO:0090642 biolink:CellularComponent microsporidian-type exospore The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore. go-plus.json http://purl.obolibrary.org/obo/GO_0090642 GO:0075001 biolink:BiologicalProcess adhesion of symbiont infection structure to host The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont infection structure to host during symbiotic interaction|attachment of symbiont infection structure to host http://purl.obolibrary.org/obo/GO_0075001 GO:0051034 biolink:MolecularActivity tRNA transmembrane transporter activity Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0051034 GO:0090643 biolink:BiologicalProcess inflorescence phyllotactic patterning The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0090643 GO:0075002 biolink:BiologicalProcess adhesion of symbiont germination tube to host The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont germination tube to host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075002 GO:0051035 biolink:MolecularActivity DNA transmembrane transporter activity Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0051035 GO:0075003 biolink:BiologicalProcess adhesion of symbiont appressorium to host The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont appressorium to host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075003 GO:0090640 biolink:BiologicalProcess phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine. go-plus.json http://purl.obolibrary.org/obo/GO_0090640 GO:0051032 biolink:MolecularActivity nucleic acid transmembrane transporter activity Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information. go-plus.json http://purl.obolibrary.org/obo/GO_0051032 GO:0090641 biolink:CellularComponent microsporidian-type endospore The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0090641 GO:0051033 biolink:MolecularActivity RNA transmembrane transporter activity Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other. Reactome:R-HSA-203906 go-plus.json http://purl.obolibrary.org/obo/GO_0051033 GO:0075004 biolink:BiologicalProcess adhesion of symbiont spore to host The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont spore to host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075004 GO:0051049 biolink:BiologicalProcess regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051049 goslim_yeast GO:0051047 biolink:BiologicalProcess positive regulation of secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. go-plus.json upregulation of secretion|up regulation of secretion|activation of secretion|stimulation of secretion|up-regulation of secretion http://purl.obolibrary.org/obo/GO_0051047 GO:0051048 biolink:BiologicalProcess negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. go-plus.json down regulation of secretion|downregulation of secretion|down-regulation of secretion|inhibition of secretion http://purl.obolibrary.org/obo/GO_0051048 NCBITaxon:4107 biolink:OrganismalEntity Solanum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4107 GO:1905220 biolink:BiologicalProcess negative regulation of platelet formation Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation. go-plus.json downregulation of platelet formation|down regulation of platelet formation|inhibition of platelet formation|negative regulation of platelet extrusion|down-regulation of platelet extrusion|down-regulation of platelet formation|downregulation of platelet extrusion|down regulation of platelet extrusion|inhibition of platelet extrusion http://purl.obolibrary.org/obo/GO_1905220 GO:1905221 biolink:BiologicalProcess positive regulation of platelet formation Any process that activates or increases the frequency, rate or extent of platelet formation. go-plus.json upregulation of platelet extrusion|upregulation of platelet formation|activation of platelet extrusion|up-regulation of platelet extrusion|activation of platelet formation|up-regulation of platelet formation|positive regulation of platelet extrusion|up regulation of platelet extrusion|up regulation of platelet formation http://purl.obolibrary.org/obo/GO_1905221 GO:1905222 biolink:BiologicalProcess atrioventricular canal morphogenesis The developmental process by which an atrioventricular canal is generated and organized. go-plus.json ependymal canal morphogenesis|canalis atrioventricularis morphogenesis|atrio-ventricular canal morphogenesis|atrial canal morphogenesis|AV canal morphogenesis|AVC morphogenesis http://purl.obolibrary.org/obo/GO_1905222 GO:1905223 biolink:BiologicalProcess epicardium morphogenesis The developmental process by which an epicardium is generated and organized. go-plus.json visceral serous pericardium of heart morphogenesis|pericardium visceral mesothelium morphogenesis|visceral serous pericardium proper morphogenesis|heart epicardium morphogenesis http://purl.obolibrary.org/obo/GO_1905223 GO:1905213 biolink:BiologicalProcess negative regulation of mitotic chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation. go-plus.json http://purl.obolibrary.org/obo/GO_1905213 GO:0090657 biolink:BiologicalProcess telomeric loop disassembly The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication. go-plus.json t-loop disassembly|T loop disassembly http://purl.obolibrary.org/obo/GO_0090657 GO:1905214 biolink:BiologicalProcess regulation of RNA binding Any process that modulates the frequency, rate or extent of RNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_1905214 GO:0090658 biolink:CellularComponent cone matrix sheath A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments. go-plus.json http://purl.obolibrary.org/obo/GO_0090658 GO:1905215 biolink:BiologicalProcess negative regulation of RNA binding Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding. go-plus.json down regulation of RNA binding|downregulation of RNA binding|down-regulation of RNA binding|inhibition of RNA binding http://purl.obolibrary.org/obo/GO_1905215 GO:0090655 biolink:MolecularActivity double-stranded/single-stranded junction telomeric DNA binding Binding to a junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang. go-plus.json http://purl.obolibrary.org/obo/GO_0090655 GO:1905216 biolink:BiologicalProcess positive regulation of RNA binding Any process that activates or increases the frequency, rate or extent of RNA binding. go-plus.json upregulation of RNA binding|up regulation of RNA binding|activation of RNA binding|up-regulation of RNA binding http://purl.obolibrary.org/obo/GO_1905216 GO:0090656 biolink:BiologicalProcess t-circle formation A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD). go-plus.json telomeric circle formation http://purl.obolibrary.org/obo/GO_0090656 GO:1905217 biolink:BiologicalProcess response to astaxanthin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus. go-plus.json response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione http://purl.obolibrary.org/obo/GO_1905217 GO:1905218 biolink:BiologicalProcess cellular response to astaxanthin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus. go-plus.json cellular response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione http://purl.obolibrary.org/obo/GO_1905218 GO:0090659 biolink:BiologicalProcess walking behavior The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg. go-plus.json locomotor gait pattern http://purl.obolibrary.org/obo/GO_0090659 GO:1905219 biolink:BiologicalProcess regulation of platelet formation Any process that modulates the frequency, rate or extent of platelet formation. go-plus.json regulation of platelet extrusion http://purl.obolibrary.org/obo/GO_1905219 GO:0051041 biolink:BiologicalProcess positive regulation of calcium-independent cell-cell adhesion Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion. go-plus.json up regulation of calcium-independent cell-cell adhesion|upregulation of calcium-independent cell-cell adhesion|stimulation of calcium-independent cell-cell adhesion|up-regulation of calcium-independent cell-cell adhesion|activation of calcium-independent cell-cell adhesion http://purl.obolibrary.org/obo/GO_0051041 GO:0051042 biolink:BiologicalProcess negative regulation of calcium-independent cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion. go-plus.json downregulation of calcium-independent cell-cell adhesion|down regulation of calcium-independent cell-cell adhesion|inhibition of calcium-independent cell-cell adhesion|down-regulation of calcium-independent cell-cell adhesion http://purl.obolibrary.org/obo/GO_0051042 GO:0090650 biolink:BiologicalProcess cellular response to oxygen-glucose deprivation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. go-plus.json cellular response to OGD http://purl.obolibrary.org/obo/GO_0090650 GO:0051040 biolink:BiologicalProcess regulation of calcium-independent cell-cell adhesion Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0051040 GO:0051045 biolink:BiologicalProcess negative regulation of membrane protein ectodomain proteolysis Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis. go-plus.json down-regulation of membrane protein ectodomain proteolysis|inhibition of membrane protein ectodomain proteolysis|down regulation of membrane protein ectodomain proteolysis|downregulation of membrane protein ectodomain proteolysis http://purl.obolibrary.org/obo/GO_0051045 GO:0090653 biolink:CellularComponent apical recycling endosome Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090653 GO:0051046 biolink:BiologicalProcess regulation of secretion Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0051046 GO:0090654 biolink:CellularComponent basolateral recycling endosome Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090654 GO:0090651 biolink:CellularComponent apical cytoplasm The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090651 GO:0051043 biolink:BiologicalProcess regulation of membrane protein ectodomain proteolysis Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). go-plus.json http://purl.obolibrary.org/obo/GO_0051043 GO:0051044 biolink:BiologicalProcess positive regulation of membrane protein ectodomain proteolysis Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis. go-plus.json activation of membrane protein ectodomain proteolysis|stimulation of membrane protein ectodomain proteolysis|up-regulation of membrane protein ectodomain proteolysis|upregulation of membrane protein ectodomain proteolysis|up regulation of membrane protein ectodomain proteolysis http://purl.obolibrary.org/obo/GO_0051044 GO:0090652 biolink:CellularComponent basolateral cytoplasm The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090652 GO:0075027 biolink:BiologicalProcess positive regulation of appressorium initiation Any process that activates or increases the frequency, rate or extent of symbiont appressorium initiation. go-plus.json positive regulation of appressorium initiation on or near host|positive regulation of initiation of appressorium on or near host http://purl.obolibrary.org/obo/GO_0075027 GO:0075028 biolink:BiologicalProcess negative regulation of appressorium initiation Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium initiation. go-plus.json negative regulation of appressorium initiation on or near host|negative regulation of initiation of appressorium on or near host http://purl.obolibrary.org/obo/GO_0075028 GO:0051058 biolink:BiologicalProcess negative regulation of small GTPase mediated signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction. go-plus.json inhibition of small GTPase mediated signal transduction|negative regulation of small GTPase-mediated signal transduction|down regulation of small GTPase mediated signal transduction|downregulation of small GTPase mediated signal transduction|down-regulation of small GTPase mediated signal transduction http://purl.obolibrary.org/obo/GO_0051058 GO:0075029 biolink:BiologicalProcess formation of appressorium germ tube hook structure The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation. go-plus.json formation of symbiont germ tube hook structure on or near host|symbiont germ tube hook structure formation on or near host|formation of germ tube tip of symbiont on or near the exterior of host|formation of symbiont germ tube hook structure for appressorium development http://purl.obolibrary.org/obo/GO_0075029 GO:0051059 biolink:MolecularActivity NF-kappaB binding Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0051059 CHEBI:5070 biolink:ChemicalSubstance flavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_5070 chebi_ph7_3 GO:0090619 biolink:CellularComponent meiotic spindle pole Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0090619 GO:1905230 biolink:BiologicalProcess response to borneol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905230 GO:1905231 biolink:BiologicalProcess cellular response to borneol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905231 GO:1905232 biolink:BiologicalProcess cellular response to L-glutamate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus. go-plus.json cellular response to L-glutamate(1-) http://purl.obolibrary.org/obo/GO_1905232 GO:1905233 biolink:BiologicalProcess response to codeine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905233 GO:1905234 biolink:BiologicalProcess cellular response to codeine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905234 GO:1905224 biolink:BiologicalProcess clathrin-coated pit assembly The aggregation, arrangement and bonding together of a set of components to form a clathrin-coated pit. go-plus.json coated pit assembly|clathrin-coated pit formation|coated pit formation http://purl.obolibrary.org/obo/GO_1905224 GO:0090624 biolink:MolecularActivity endoribonuclease activity, cleaving miRNA-paired mRNA Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0090624 GO:1905225 biolink:BiologicalProcess response to thyrotropin-releasing hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. go-plus.json response to protirelin|response to TRH http://purl.obolibrary.org/obo/GO_1905225 GO:0090625 biolink:BiologicalProcess mRNA cleavage involved in gene silencing by siRNA The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0090625 GO:1905226 biolink:BiologicalProcess regulation of adhesion of symbiont to host epithelial cell Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_1905226 GO:0090622 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090622 GO:1905227 biolink:BiologicalProcess negative regulation of adhesion of symbiont to host epithelial cell Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell. go-plus.json downregulation of adhesion of symbiont to host epithelial cell|down regulation of adhesion of symbiont to host epithelial cell|inhibition of adhesion of symbiont to host epithelial cell|down-regulation of adhesion of symbiont to host epithelial cell http://purl.obolibrary.org/obo/GO_1905227 GO:0090623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090623 GO:1905228 biolink:BiologicalProcess positive regulation of adhesion of symbiont to host epithelial cell Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell. go-plus.json upregulation of adhesion of symbiont to host epithelial cell|up-regulation of adhesion of symbiont to host epithelial cell|activation of adhesion of symbiont to host epithelial cell|up regulation of adhesion of symbiont to host epithelial cell http://purl.obolibrary.org/obo/GO_1905228 GO:0090628 biolink:BiologicalProcess plant epidermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0090628 GO:1905229 biolink:BiologicalProcess cellular response to thyrotropin-releasing hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. go-plus.json cellular response to protirelin|cellular response to TRH http://purl.obolibrary.org/obo/GO_1905229 GO:0090629 biolink:BiologicalProcess lagging strand initiation The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started. go-plus.json http://purl.obolibrary.org/obo/GO_0090629 GO:0090626 biolink:BiologicalProcess plant epidermis morphogenesis The process in which the anatomical structures of the plant epidermis are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0090626 GO:0090627 biolink:BiologicalProcess plant epidermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090627 GO:0051052 biolink:BiologicalProcess regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. go-plus.json regulation of DNA metabolism http://purl.obolibrary.org/obo/GO_0051052 goslim_yeast GO:0075020 biolink:BiologicalProcess obsolete calcium or calmodulin-mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont calcium or calmodulin-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json Ca++ or calmodulin-mediated activation of appressorium formation|Ca2+ or calmodulin-mediated activation of appressorium formation http://purl.obolibrary.org/obo/GO_0075020 GO:0051053 biolink:BiologicalProcess negative regulation of DNA metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. go-plus.json inhibition of DNA metabolic process|negative regulation of DNA metabolism|down regulation of DNA metabolic process|downregulation of DNA metabolic process|down-regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0051053 GO:0075021 biolink:BiologicalProcess obsolete cAMP-mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cAMP mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json cyclic AMP mediated activation of appressorium formation http://purl.obolibrary.org/obo/GO_0075021 GO:0051050 biolink:BiologicalProcess positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of transport|activation of transport|stimulation of transport|up-regulation of transport|upregulation of transport http://purl.obolibrary.org/obo/GO_0051050 GO:0051051 biolink:BiologicalProcess negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down regulation of transport|downregulation of transport|down-regulation of transport|inhibition of transport http://purl.obolibrary.org/obo/GO_0051051 GO:0075022 biolink:BiologicalProcess obsolete ethylene-mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075022 GO:0090620 biolink:CellularComponent obsolete APC-Cdc20 complex OBSOLETE. An anaphase promoting complex bound to the fizzy family APC activator Cdc20/Slp1 which regulates the metaphase anaphase transition by activating the APC/C to target the anaphase inhibitor securin and promotes sister chromatid separation. go-plus.json APC-fizzy complex|APC-Slp1 complex|mitotic anaphase promotic complex http://purl.obolibrary.org/obo/GO_0090620 GO:0051056 biolink:BiologicalProcess regulation of small GTPase mediated signal transduction Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. go-plus.json regulation of small GTPase-mediated signal transduction http://purl.obolibrary.org/obo/GO_0051056 GO:0075023 biolink:BiologicalProcess obsolete MAPK-mediated regulation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json mitogen-activated protein kinase-mediated activation of appressorium formation http://purl.obolibrary.org/obo/GO_0075023 GO:0090621 biolink:CellularComponent obsolete APC-fizzy-related complex OBSOLETE. An anaphase promoting complex bound to the fizzy-related family APC activator FZR1/Cdh1/Srw1 that regulates mitotic exit by activating the APC/C to target mitotic cyclins for destruction during anaphase and telophase. Is also active during G1. go-plus.json APC-Hct1/Cdh1 complex|APC-Srw1 complex http://purl.obolibrary.org/obo/GO_0090621 GO:0051057 biolink:BiologicalProcess positive regulation of small GTPase mediated signal transduction Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction. go-plus.json up-regulation of small GTPase mediated signal transduction|positive regulation of small GTPase-mediated signal transduction|upregulation of small GTPase mediated signal transduction|up regulation of small GTPase mediated signal transduction|activation of small GTPase mediated signal transduction|stimulation of small GTPase mediated signal transduction http://purl.obolibrary.org/obo/GO_0051057 GO:0075024 biolink:BiologicalProcess obsolete phospholipase C-mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075024 GO:0051054 biolink:BiologicalProcess positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. go-plus.json up-regulation of DNA metabolic process|upregulation of DNA metabolic process|positive regulation of DNA metabolism|up regulation of DNA metabolic process|activation of DNA metabolic process|stimulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0051054 GO:0075025 biolink:BiologicalProcess initiation of appressorium formation The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json initiation of appressorium by symbiont on or near host|initiation of symbiont appressorium on or near host|appressorium initiation on or near host|initiation of appressorium on or near host http://purl.obolibrary.org/obo/GO_0075025 GO:0051055 biolink:BiologicalProcess negative regulation of lipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. go-plus.json downregulation of lipid biosynthetic process|down regulation of lipid biosynthetic process|inhibition of lipid biosynthetic process|negative regulation of lipid anabolism|negative regulation of lipogenesis|negative regulation of lipid synthesis|negative regulation of lipid formation|down-regulation of lipid biosynthetic process|negative regulation of lipid biosynthesis http://purl.obolibrary.org/obo/GO_0051055 GO:0075026 biolink:BiologicalProcess regulation of appressorium initiation Any process that modulates the frequency, rate or extent of symbiont appressorium initiation. go-plus.json regulation of initiation of appressorium on or near host|regulation of appressorium initiation on or near host http://purl.obolibrary.org/obo/GO_0075026 GO:0075016 biolink:BiologicalProcess appressorium formation The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface. go-plus.json appressorium formation on or near host|formation of an appressorium by symbiont on or near host|appressorium formation for entry into host, on or near host http://purl.obolibrary.org/obo/GO_0075016 GO:0075017 biolink:BiologicalProcess regulation of appressorium formation Any process that modulates the frequency, rate or extent of symbiont appressorium formation. go-plus.json regulation of appressorium formation on or near host http://purl.obolibrary.org/obo/GO_0075017 GO:0051069 biolink:BiologicalProcess galactomannan metabolic process The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units. go-plus.json galactomannan metabolism http://purl.obolibrary.org/obo/GO_0051069 GO:0075018 biolink:BiologicalProcess positive regulation of appressorium formation Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation. go-plus.json positive regulation of appressorium formation on or near host http://purl.obolibrary.org/obo/GO_0075018 GO:0075019 biolink:BiologicalProcess negative regulation of appressorium formation Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation. go-plus.json negative regulation of appressorium formation on or near host http://purl.obolibrary.org/obo/GO_0075019 GO:1905240 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation. go-plus.json down-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|inhibition of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation http://purl.obolibrary.org/obo/GO_1905240 GO:1905241 biolink:BiologicalProcess positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation. go-plus.json upregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|activation of canonical Wnt signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|activation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation http://purl.obolibrary.org/obo/GO_1905241 GO:1905242 biolink:BiologicalProcess response to 3,3',5-triiodo-L-thyronine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus. go-plus.json response to Liothyroninum|response to Liothyronine|response to Liothyronin http://purl.obolibrary.org/obo/GO_1905242 GO:1905243 biolink:BiologicalProcess cellular response to 3,3',5-triiodo-L-thyronine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus. go-plus.json cellular response to Liothyronin|cellular response to Liothyroninum|cellular response to Liothyronine http://purl.obolibrary.org/obo/GO_1905243 GO:1905244 biolink:BiologicalProcess regulation of modification of synaptic structure Any process that modulates the frequency, rate or extent of modification of synaptic structure. go-plus.json regulation of synapse remodelling http://purl.obolibrary.org/obo/GO_1905244 goslim_synapse GO:1905245 biolink:BiologicalProcess regulation of aspartic-type peptidase activity Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905245 GO:1905235 biolink:BiologicalProcess response to quercetin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905235 GO:0090635 biolink:CellularComponent extracellular core region of desmosome The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner. go-plus.json desmoglea http://purl.obolibrary.org/obo/GO_0090635 GO:0090636 biolink:CellularComponent outer dense plaque of desmosome The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090636 GO:1905236 biolink:BiologicalProcess cellular response to quercetin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905236 GO:1905237 biolink:BiologicalProcess response to cyclosporin A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus. go-plus.json response to cyclophilin http://purl.obolibrary.org/obo/GO_1905237 GO:0090633 biolink:MolecularActivity keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN. go-plus.json CMP-KDN synthetase activity|cytidine 5'-monophospho-2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid synthetase activity http://purl.obolibrary.org/obo/GO_0090633 GO:1905238 biolink:BiologicalProcess cellular response to cyclosporin A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus. go-plus.json cellular response to cyclophilin http://purl.obolibrary.org/obo/GO_1905238 GO:0090634 biolink:BiologicalProcess microglial cell mediated cytotoxicity The directed killing of a target cell by a microglial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090634 GO:1905239 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway involved in osteoblast differentiation Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation. go-plus.json regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation http://purl.obolibrary.org/obo/GO_1905239 GO:0090639 biolink:BiologicalProcess phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine. go-plus.json http://purl.obolibrary.org/obo/GO_0090639 GO:0051060 biolink:MolecularActivity pullulanase activity Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen. MetaCyc:RXN-1824|EC:3.2.1.41 go-plus.json R-enzyme|pullulan 6-glucanohydrolase activity|limit dextrinase|alpha-dextrin endo-1,6-alpha-glucosidase activity|pullulan alpha-1,6-glucanohydrolase activity|amylopectin 6-glucanohydrolase activity|bacterial debranching enzyme|debranching enzyme activity http://purl.obolibrary.org/obo/GO_0051060 GO:0090637 biolink:CellularComponent inner dense plaque of desmosome The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090637 GO:0090638 biolink:BiologicalProcess phosphatidylcholine biosynthesis from phosphatidylethanolamine The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations. go-plus.json http://purl.obolibrary.org/obo/GO_0090638 GO:0051063 biolink:MolecularActivity CDP reductase activity Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin. MetaCyc:CDPREDUCT-RXN go-plus.json CDP reduction http://purl.obolibrary.org/obo/GO_0051063 GO:0051064 biolink:MolecularActivity TTP reductase activity Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. EC:1.17.4.- go-plus.json TTP reduction http://purl.obolibrary.org/obo/GO_0051064 GO:0051061 biolink:MolecularActivity ADP reductase activity Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin. RHEA:28034|MetaCyc:ADPREDUCT-RXN go-plus.json ADP reduction http://purl.obolibrary.org/obo/GO_0051061 GO:0075010 biolink:BiologicalProcess regulation of germ tube formation Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075010 GO:0051062 biolink:MolecularActivity UDP reductase activity Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin. RHEA:28026|MetaCyc:UDPREDUCT-RXN go-plus.json UDP reduction http://purl.obolibrary.org/obo/GO_0051062 GO:0075011 biolink:BiologicalProcess positive regulation of germ tube formation Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of germ tube formation on or near host http://purl.obolibrary.org/obo/GO_0075011 GO:0051067 biolink:BiologicalProcess dihydropteridine metabolic process The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4. go-plus.json 6,7-dihydropteridine metabolic process|dihydropteridine reduction|dihydropteridine metabolism http://purl.obolibrary.org/obo/GO_0051067 GO:0075012 biolink:BiologicalProcess negative regulation of germ tube formation Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of germ tube formation on or near host http://purl.obolibrary.org/obo/GO_0075012 GO:0090631 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090631 GO:0090632 biolink:MolecularActivity N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc. go-plus.json CMP-Neu5Gc synthetase activity http://purl.obolibrary.org/obo/GO_0090632 GO:0051068 biolink:BiologicalProcess dihydrolipoamide metabolic process The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor. go-plus.json dihydrothioctamide metabolism|dihydrolipoamide metabolism|dihydrolipoamide reduction|dihydrothioctamide metabolic process http://purl.obolibrary.org/obo/GO_0051068 GO:0075013 biolink:BiologicalProcess obsolete growth or development of symbiont on or near host phyllosphere OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont on or near host phyllosphere http://purl.obolibrary.org/obo/GO_0075013 CHEBI:5078 biolink:ChemicalSubstance flavonol go-plus.json http://purl.obolibrary.org/obo/CHEBI_5078 chebi_ph7_3 GO:0051065 biolink:MolecularActivity CTP reductase activity Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. EC:1.17.4.- go-plus.json CTP reduction http://purl.obolibrary.org/obo/GO_0051065 GO:0075014 biolink:BiologicalProcess obsolete growth or development of symbiont on or near host rhizosphere OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont on or near host rhizosphere http://purl.obolibrary.org/obo/GO_0075014 GO:0090630 biolink:BiologicalProcess activation of GTPase activity Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP. go-plus.json Ras GTPase activation|Rap GTPase activation|Cdc42 GTPase activation|Ran GTPase activation|activation of Ras GTPase activity|Ral GTPase activation|activation of Rap GTPase activity|activation of Cdc42 GTPase activity|Rho GTPase activation|activation of Ran GTPase activity|activation of Ral GTPase activity|ARF GTPase activation|Rac GTPase activation|activation of Rho GTPase activity|Rab GTPase activation|activation of ARF GTPase activity|activation of Rac GTPase activity|activation of Rab GTPase activity http://purl.obolibrary.org/obo/GO_0090630 GO:0051066 biolink:BiologicalProcess dihydrobiopterin metabolic process The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions. go-plus.json dihydropterin metabolism|7,8-dihydrobiopterin metabolic process|6,7-dihydrobiopterin metabolic process|dihydropterin metabolic process|dihydrobiopterin reduction http://purl.obolibrary.org/obo/GO_0051066 GO:0075015 biolink:BiologicalProcess formation of infection structure The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation by symbiont of infection structure on or near host|formation of host penetration structure|formation of infection structure on or near host|formation of host infection structure http://purl.obolibrary.org/obo/GO_0075015 CHEBI:55549 biolink:ChemicalSubstance dalpatein go-plus.json http://purl.obolibrary.org/obo/CHEBI_55549 CHEBI:79516 biolink:ChemicalSubstance Nonylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_79516 GO:2000225 biolink:BiologicalProcess negative regulation of testosterone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_2000225 GO:2000226 biolink:BiologicalProcess regulation of pancreatic A cell differentiation Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation. go-plus.json regulation of pancreatic alpha cell differentiation http://purl.obolibrary.org/obo/GO_2000226 GO:2000227 biolink:BiologicalProcess negative regulation of pancreatic A cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. go-plus.json negative regulation of pancreatic alpha cell differentiation http://purl.obolibrary.org/obo/GO_2000227 GO:2000228 biolink:BiologicalProcess positive regulation of pancreatic A cell differentiation Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation. go-plus.json positive regulation of pancreatic alpha cell differentiation http://purl.obolibrary.org/obo/GO_2000228 GO:0016628 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. Reactome:R-HSA-9661745|Reactome:R-HSA-9661726|EC:1.3.1.-|Reactome:R-HSA-4755572|Reactome:R-HSA-4419979 go-plus.json http://purl.obolibrary.org/obo/GO_0016628 GO:2000229 biolink:BiologicalProcess regulation of pancreatic stellate cell proliferation Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000229 GO:0016629 biolink:MolecularActivity 12-oxophytodienoate reductase activity Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH. RHEA:21888|EC:1.3.1.42|MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN|KEGG_REACTION:R03401 go-plus.json 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity|12-oxo-phytodienoic acid reductase activity|12-oxo-phytodienoate reductase activity http://purl.obolibrary.org/obo/GO_0016629 GO:0016624 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide. EC:1.2.4.- go-plus.json oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016624 GO:0016625 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.2.7.- go-plus.json oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0016625 GO:0016626 biolink:MolecularActivity obsolete oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome. go-plus.json oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016626 GO:0016627 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.3.-.-|Reactome:R-HSA-2995334|Reactome:R-HSA-9661710 go-plus.json oxidoreductase activity, acting on the CH-CH group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016627 GO:2000220 biolink:BiologicalProcess regulation of pseudohyphal growth Any process that modulates the frequency, rate or extent of pseudohyphal growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000220 GO:0016620 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.2.1.-|Reactome:R-HSA-1222583 go-plus.json http://purl.obolibrary.org/obo/GO_0016620 GO:2000221 biolink:BiologicalProcess negative regulation of pseudohyphal growth Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000221 GO:0016621 biolink:MolecularActivity cinnamoyl-CoA reductase activity Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+. MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN|EC:1.2.1.44|RHEA:10620 go-plus.json cinnamoyl-CoA:NADPH reductase activity|cinnamoyl-coenzyme A reductase activity|p-hydroxycinnamoyl coenzyme A reductase activity|feruloyl coenzyme A reductase activity|cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)|feruloyl-CoA reductase activity|cinnamoyl CoA reductase activity|ferulyl-CoA reductase activity http://purl.obolibrary.org/obo/GO_0016621 GO:2000222 biolink:BiologicalProcess positive regulation of pseudohyphal growth Any process that activates or increases the frequency, rate or extent of pseudohyphal growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000222 GO:0016622 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome. EC:1.2.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016622 GO:2000223 biolink:BiologicalProcess regulation of BMP signaling pathway involved in heart jogging Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging. go-plus.json regulation of BMP signalling pathway involved in heart jogging pathway involved in somitogenesis http://purl.obolibrary.org/obo/GO_2000223 GO:0016623 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen. EC:1.2.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016623 GO:2000224 biolink:BiologicalProcess regulation of testosterone biosynthetic process Any process that modulates the frequency, rate or extent of testosterone biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_2000224 CHEBI:31577 biolink:ChemicalSubstance ethylenediamine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_31577 NCBITaxon:4143 biolink:OrganismalEntity Lamiales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4143 GO:2000236 biolink:BiologicalProcess negative regulation of tRNA processing Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing. go-plus.json negative regulation of tRNA maturation http://purl.obolibrary.org/obo/GO_2000236 GO:2000237 biolink:BiologicalProcess positive regulation of tRNA processing Any process that activates or increases the frequency, rate or extent of tRNA processing. go-plus.json positive regulation of tRNA maturation http://purl.obolibrary.org/obo/GO_2000237 GO:2000238 biolink:BiologicalProcess regulation of tRNA export from nucleus Any process that modulates the frequency, rate or extent of tRNA export from nucleus. go-plus.json regulation of tRNA export out of nucleus|regulation of tRNA-nucleus export|regulation of tRNA export from cell nucleus|regulation of tRNA transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_2000238 GO:2000239 biolink:BiologicalProcess negative regulation of tRNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus. go-plus.json negative regulation of tRNA transport from nucleus to cytoplasm|negative regulation of tRNA-nucleus export|negative regulation of tRNA export out of nucleus|negative regulation of tRNA export from cell nucleus http://purl.obolibrary.org/obo/GO_2000239 GO:0016639 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. EC:1.4.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016639 GO:0016635 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound. EC:1.3.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0016635 GO:0016636 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.3.7.- go-plus.json oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0016636 GO:2000230 biolink:BiologicalProcess negative regulation of pancreatic stellate cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000230 GO:0016637 biolink:MolecularActivity obsolete oxidoreductase activity, acting on the CH-CH group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen. go-plus.json oxidoreductase activity, acting on the CH-CH group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016637 GO:0016638 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.4.-.- go-plus.json oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016638 GO:2000231 biolink:BiologicalProcess positive regulation of pancreatic stellate cell proliferation Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000231 GO:2000232 biolink:BiologicalProcess regulation of rRNA processing Any process that modulates the frequency, rate or extent of rRNA processing. go-plus.json regulation of 35S primary transcript processing http://purl.obolibrary.org/obo/GO_2000232 GO:0016631 biolink:MolecularActivity enoyl-[acyl-carrier-protein] reductase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+. MetaCyc:RXN1G-2527|EC:1.3.1.9|Wikipedia:Enoyl-acyl_carrier_protein_reductase|MetaCyc:1.3.1.39-RXN|MetaCyc:RXN1G-3613|MetaCyc:RXN1G-3667|MetaCyc:RXN1G-2544|MetaCyc:RXN1G-45|MetaCyc:RXN1G-3641|MetaCyc:RXN1G-3256|MetaCyc:1.3.1.10-RXN|MetaCyc:RXN1G-3993|MetaCyc:RXN1G-3232|MetaCyc:RXN1G-4140 go-plus.json acyl-ACP dehydrogenase activity|enoyl-acyl carrier protein reductase|enoyl-[acyl-carrier protein] reductase activity|enoyl-ACP reductase activity http://purl.obolibrary.org/obo/GO_0016631 GO:2000233 biolink:BiologicalProcess negative regulation of rRNA processing Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing. go-plus.json negative regulation of 35S primary transcript processing http://purl.obolibrary.org/obo/GO_2000233 GO:0016632 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome. EC:1.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016632 GO:0016633 biolink:MolecularActivity galactonolactone dehydrogenase activity Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c. RHEA:32367|EC:1.3.2.3|MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN go-plus.json L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity|L-galactono-1,4-lactone dehydrogenase activity|GLDHase activity|L-galactono-gamma-lactone dehydrogenase activity|L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity|GLDase activity|L-galactonolactone dehydrogenase activity http://purl.obolibrary.org/obo/GO_0016633 GO:2000234 biolink:BiologicalProcess positive regulation of rRNA processing Any process that activates or increases the frequency, rate or extent of rRNA processing. go-plus.json positive regulation of 35S primary transcript processing http://purl.obolibrary.org/obo/GO_2000234 GO:2000235 biolink:BiologicalProcess regulation of tRNA processing Any process that modulates the frequency, rate or extent of tRNA processing. go-plus.json regulation of tRNA maturation http://purl.obolibrary.org/obo/GO_2000235 GO:0016634 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen. EC:1.3.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016634 NCBITaxon:4155 biolink:OrganismalEntity Erythranthe guttata go-plus.json Mimulus guttatus subsp. guttatus|yellow monkey flower|spotted monkey flower|Mimulus guttatus|common monkey flower http://purl.obolibrary.org/obo/NCBITaxon_4155 CHEBI:55534 biolink:ChemicalSubstance (R)-2-hydroxy-4-methylpentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55534 CHEBI:55535 biolink:ChemicalSubstance (R)-2-hydroxy-4-methylpentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55535 chebi_ph7_3 GO:0016630 biolink:MolecularActivity protochlorophyllide reductase activity Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+. EC:1.3.1.33|RHEA:11132|MetaCyc:RXN1F-10 go-plus.json protochlorophyllide photooxidoreductase activity|protochlorophyllide oxidoreductase activity|NADPH2-protochlorophyllide oxidoreductase activity|NADPH-protochlorophyllide oxidoreductase activity|chlorophyllide-a:NADP+ 7,8-oxidoreductase activity|NADPH-protochlorophyllide reductase activity http://purl.obolibrary.org/obo/GO_0016630 NCBITaxon:4113 biolink:OrganismalEntity Solanum tuberosum go-plus.json potatoes|potato http://purl.obolibrary.org/obo/NCBITaxon_4113 GO:2000247 biolink:BiologicalProcess positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000247 GO:2000248 biolink:BiologicalProcess negative regulation of establishment or maintenance of neuroblast polarity Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. go-plus.json negative regulation of establishment and/or maintenance of neuroblast cell polarity http://purl.obolibrary.org/obo/GO_2000248 GO:2000249 biolink:BiologicalProcess regulation of actin cytoskeleton reorganization Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization. go-plus.json regulation of actin cytoskeleton reorganisation|regulation of actin cytoskeleton remodeling http://purl.obolibrary.org/obo/GO_2000249 GO:0016606 biolink:CellularComponent LYSP100-associated nuclear domain A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies. go-plus.json LANDs http://purl.obolibrary.org/obo/GO_0016606 GO:0016607 biolink:CellularComponent nuclear speck A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. go-plus.json nuclear speckles|splicing speckle|speckle domain|speckle focus|nuclear speckle http://purl.obolibrary.org/obo/GO_0016607 GO:0016608 biolink:MolecularActivity growth hormone-releasing hormone activity The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland. go-plus.json GHRF activity|GHRH activity http://purl.obolibrary.org/obo/GO_0016608 GO:0016609 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016609 GO:0016602 biolink:CellularComponent CCAAT-binding factor complex A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5. go-plus.json nuclear transcription factor Y complex|CBF complex|NF-Y transcription factor complex http://purl.obolibrary.org/obo/GO_0016602 GO:0016603 biolink:MolecularActivity glutaminyl-peptide cyclotransferase activity Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3. EC:2.3.2.5|MetaCyc:GLUTAMINYL-PEPTIDE-CYCLOTRANSFERASE-RXN|RHEA:23652 go-plus.json glutaminyl-tRNA cyclotransferase activity|glutaminyl cyclase activity|L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)|glutaminyl-transfer ribonucleate cyclotransferase activity http://purl.obolibrary.org/obo/GO_0016603 GO:2000240 biolink:BiologicalProcess positive regulation of tRNA export from nucleus Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus. go-plus.json positive regulation of tRNA export from cell nucleus|positive regulation of tRNA export out of nucleus|positive regulation of tRNA-nucleus export|positive regulation of tRNA transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_2000240 GO:2000241 biolink:BiologicalProcess regulation of reproductive process Any process that modulates the frequency, rate or extent of reproductive process. go-plus.json http://purl.obolibrary.org/obo/GO_2000241 GO:0016604 biolink:CellularComponent nuclear body Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. NIF_Subcellular:sao505137457 go-plus.json http://purl.obolibrary.org/obo/GO_0016604 CHEBI:31550 biolink:ChemicalSubstance epothilone B go-plus.json http://purl.obolibrary.org/obo/CHEBI_31550 chebi_ph7_3 GO:2000242 biolink:BiologicalProcess negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. go-plus.json http://purl.obolibrary.org/obo/GO_2000242 GO:0016605 biolink:CellularComponent PML body A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. go-plus.json nuclear dot|PML NB|ND10|PML nuclear body http://purl.obolibrary.org/obo/GO_0016605 GO:2000243 biolink:BiologicalProcess positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of reproductive process. go-plus.json http://purl.obolibrary.org/obo/GO_2000243 GO:2000244 biolink:BiologicalProcess regulation of FtsZ-dependent cytokinesis Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis. go-plus.json regulation of prokaryotic fission|regulation of prokaryote-type cytokinesis http://purl.obolibrary.org/obo/GO_2000244 GO:2000245 biolink:BiologicalProcess negative regulation of FtsZ-dependent cytokinesis Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis. go-plus.json negative regulation of prokaryotic fission|negative regulation of prokaryote-type cytokinesis http://purl.obolibrary.org/obo/GO_2000245 GO:0016600 biolink:CellularComponent flotillin complex A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae. go-plus.json http://purl.obolibrary.org/obo/GO_0016600 GO:2000246 biolink:BiologicalProcess positive regulation of FtsZ-dependent cytokinesis Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis. go-plus.json positive regulation of prokaryotic fission|positive regulation of prokaryote-type cytokinesis http://purl.obolibrary.org/obo/GO_2000246 GO:0016601 biolink:BiologicalProcess Rac protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state. go-plus.json Rac mediated signal transduction http://purl.obolibrary.org/obo/GO_0016601 CHEBI:55517 biolink:ChemicalSubstance trichothecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_55517 chebi_ph7_3 CHEBI:55514 biolink:ChemicalSubstance laminaritriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55514 chebi_ph7_3 CHEBI:80536 biolink:ChemicalSubstance juvenile hormone III acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80536 GO:2000258 biolink:BiologicalProcess negative regulation of protein activation cascade Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade. go-plus.json negative regulation of protein activation pathway|negative regulation of protein activitory cascade http://purl.obolibrary.org/obo/GO_2000258 GO:2000259 biolink:BiologicalProcess positive regulation of protein activation cascade Any process that activates or increases the frequency, rate or extent of protein activation cascade. go-plus.json positive regulation of protein activitory cascade|positive regulation of protein activation pathway http://purl.obolibrary.org/obo/GO_2000259 CHEBI:80535 biolink:ChemicalSubstance methyl farnesoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_80535 chebi_ph7_3 GO:0016617 biolink:MolecularActivity 4-oxoproline reductase activity Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+. MetaCyc:4-OXOPROLINE-REDUCTASE-RXN|RHEA:13601|EC:1.1.1.104 go-plus.json hydroxyproline oxidase activity|4-hydroxy-L-proline:NAD+ oxidoreductase activity|hydroxy-L-proline oxidase activity http://purl.obolibrary.org/obo/GO_0016617 GO:0016618 biolink:MolecularActivity hydroxypyruvate reductase activity Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+. MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN|EC:1.1.1.81|RHEA:18657|MetaCyc:RXN0-300 go-plus.json beta-hydroxypyruvate reductase activity|D-glycerate dehydrogenase activity|D-glycerate:NADP+ 2-oxidoreductase activity|NADH:hydroxypyruvate reductase activity http://purl.obolibrary.org/obo/GO_0016618 GO:0016619 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016619 GO:2000250 biolink:BiologicalProcess negative regulation of actin cytoskeleton reorganization Any process that stops, prevents, or reduces the frequency, rate or extent of actin cytoskeleton reorganization. go-plus.json negative regulation of actin cytoskeleton reorganisation|negative regulation of actin cytoskeleton remodeling http://purl.obolibrary.org/obo/GO_2000250 GO:0016613 biolink:CellularComponent vanadium-iron nitrogenase complex An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer. go-plus.json vanadium-iron nitrogenase activity http://purl.obolibrary.org/obo/GO_0016613 GO:0016614 biolink:MolecularActivity oxidoreductase activity, acting on CH-OH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.1.-.-|Reactome:R-HSA-1500781 go-plus.json oxidoreductase activity, acting on the CH-OH group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016614 GO:2000251 biolink:BiologicalProcess positive regulation of actin cytoskeleton reorganization Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization. go-plus.json positive regulation of actin cytoskeleton reorganisation|positive regulation of actin cytoskeleton remodeling http://purl.obolibrary.org/obo/GO_2000251 GO:2000252 biolink:BiologicalProcess negative regulation of feeding behavior Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. go-plus.json negative regulation of drinking|negative regulation of eating|negative regulation of feeding behaviour|negative regulation of behavioural response to food|negative regulation of behavioral response to food http://purl.obolibrary.org/obo/GO_2000252 GO:0016615 biolink:MolecularActivity malate dehydrogenase activity Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate. go-plus.json http://purl.obolibrary.org/obo/GO_0016615 GO:0016616 biolink:MolecularActivity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP. Reactome:R-HSA-975629|EC:1.1.1.- go-plus.json glycolate reductase|NADH-dependent glyoxylate reductase|glyoxylic acid reductase http://purl.obolibrary.org/obo/GO_0016616 GO:2000253 biolink:BiologicalProcess positive regulation of feeding behavior Any process that activates or increases the frequency, rate or extent of feeding behavior. go-plus.json positive regulation of feeding behaviour|positive regulation of eating|positive regulation of drinking|positive regulation of behavioural response to food|positive regulation of behavioral response to food http://purl.obolibrary.org/obo/GO_2000253 UBERON:0008713 biolink:AnatomicalEntity pectoral girdle and thoracic body wall skeletal muscle go-plus.json http://purl.obolibrary.org/obo/UBERON_0008713 GO:2000254 biolink:BiologicalProcess regulation of male germ cell proliferation Any process that modulates the frequency, rate or extent of male germ cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000254 GO:0016610 biolink:CellularComponent nitrogenase complex An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0016610 goslim_pir UBERON:0008715 biolink:AnatomicalEntity muscle tissue of prostate A muscle tissue that is part of a prostate gland. go-plus.json prostatic musclular tissue|prostate gland muscle tissue|prostate muscle tissue|prostatic muscle http://purl.obolibrary.org/obo/UBERON_0008715 GO:2000255 biolink:BiologicalProcess negative regulation of male germ cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000255 GO:0016611 biolink:CellularComponent iron-iron nitrogenase complex An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0016611 GO:2000256 biolink:BiologicalProcess positive regulation of male germ cell proliferation Any process that activates or increases the frequency, rate or extent of male germ cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000256 GO:2000257 biolink:BiologicalProcess regulation of protein activation cascade Any process that modulates the frequency, rate or extent of protein activation cascade. go-plus.json regulation of protein activation pathway|regulation of protein activitory cascade http://purl.obolibrary.org/obo/GO_2000257 GO:0016612 biolink:CellularComponent molybdenum-iron nitrogenase complex An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer. go-plus.json molybdenum-iron nitrogenase activity http://purl.obolibrary.org/obo/GO_0016612 CHEBI:55513 biolink:ChemicalSubstance 2-deoxy-D-ribofuranose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55513 RO:0011002 biolink:OntologyClass regulates activity of The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. RO:0011002 go-plus.json http://purl.obolibrary.org/obo/RO_0011002 CHEBI:55505 biolink:ChemicalSubstance 1,2-benzisothiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_55505 CHEBI:80545 biolink:ChemicalSubstance indolylmethyl desulfoglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_80545 chebi_ph7_3 UBERON:0008789 biolink:AnatomicalEntity cranial fossa Any of the three large depressions in the posterior, middle, and anterior aspects of the floor of the cranial cavity go-plus.json http://purl.obolibrary.org/obo/UBERON_0008789 UBERON:0008780 biolink:AnatomicalEntity inner cell mass derived epiblast An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers go-plus.json embryonic epiblast http://purl.obolibrary.org/obo/UBERON_0008780 UBERON:0008781 biolink:AnatomicalEntity blastodisc derived epiblast An epiblast (generic) that develops_from a blastodisc. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008781 UBERON:0008783 biolink:AnatomicalEntity dorsal venous arch The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein. go-plus.json arcus venosus dorsalis pedis|arcus venosus dorsalis pedis|dorsal venous arch of foot http://purl.obolibrary.org/obo/UBERON_0008783 UBERON:0008784 biolink:AnatomicalEntity lower limb segment A limb segment that is part of a hindlimb. go-plus.json free lower limb subdivision|subdivision of free lower limb|segment of free lower limb|free lower limb segment http://purl.obolibrary.org/obo/UBERON_0008784 UBERON:0008785 biolink:AnatomicalEntity upper limb segment A limb segment that is part of a forelimb. go-plus.json free upper limb subdivision|subdivision of free upper limb|segment of free upper limb|free upper limb segment http://purl.obolibrary.org/obo/UBERON_0008785 CHEBI:31549 biolink:ChemicalSubstance epothilone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_31549 chebi_ph7_3 UBERON:0008772 biolink:AnatomicalEntity proximal epiphysis of tibia A proximal epiphysis that is part of a tibia. go-plus.json upper end of tibia|head of tibia|proximal end of tibia|proximal tibial epiphysis http://purl.obolibrary.org/obo/UBERON_0008772 UBERON:0008775 biolink:AnatomicalEntity proximal epiphysis of fibula A proximal epiphysis that is part of a fibula. go-plus.json fibular head|head of fibula|upper end of fibula|caput fibulae|proximal end of fibula http://purl.obolibrary.org/obo/UBERON_0008775 GO:2000203 biolink:BiologicalProcess regulation of ribosomal large subunit export from nucleus Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus. go-plus.json regulation of ribosomal large subunit export from cell nucleus|regulation of ribosomal large subunit transport from nucleus to cytoplasm|regulation of ribosomal large subunit export out of nucleus|regulation of ribosomal large subunit-nucleus export|regulation of 60S ribosomal subunit export from nucleus|regulation of 50S ribosomal subunit export from nucleus http://purl.obolibrary.org/obo/GO_2000203 GO:2000204 biolink:BiologicalProcess negative regulation of ribosomal large subunit export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus. go-plus.json negative regulation of ribosomal large subunit export out of nucleus|negative regulation of 60S ribosomal subunit export from nucleus|negative regulation of 50S ribosomal subunit export from nucleus|negative regulation of ribosomal large subunit-nucleus export|negative regulation of ribosomal large subunit transport from nucleus to cytoplasm|negative regulation of ribosomal large subunit export from cell nucleus http://purl.obolibrary.org/obo/GO_2000204 GO:2000205 biolink:BiologicalProcess positive regulation of ribosomal large subunit export from nucleus Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus. go-plus.json positive regulation of ribosomal large subunit export from cell nucleus|positive regulation of 60S ribosomal subunit export from nucleus|positive regulation of 50S ribosomal subunit export from nucleus|positive regulation of ribosomal large subunit transport from nucleus to cytoplasm|positive regulation of ribosomal large subunit-nucleus export|positive regulation of ribosomal large subunit export out of nucleus http://purl.obolibrary.org/obo/GO_2000205 GO:2000206 biolink:BiologicalProcess regulation of ribosomal small subunit export from nucleus Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus. go-plus.json regulation of ribosomal small subunit-nucleus export|regulation of ribosomal small subunit export out of nucleus|regulation of ribosomal small subunit export from cell nucleus|regulation of ribosomal small subunit transport from nucleus to cytoplasm|regulation of 40S ribosomal subunit export from nucleus|regulation of 30S ribosomal subunit export from nucleus http://purl.obolibrary.org/obo/GO_2000206 GO:2000207 biolink:BiologicalProcess negative regulation of ribosomal small subunit export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus. go-plus.json negative regulation of ribosomal small subunit export from cell nucleus|negative regulation of 40S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit transport from nucleus to cytoplasm|negative regulation of 30S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit export out of nucleus|negative regulation of ribosomal small subunit-nucleus export http://purl.obolibrary.org/obo/GO_2000207 GO:2000208 biolink:BiologicalProcess positive regulation of ribosomal small subunit export from nucleus Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus. go-plus.json positive regulation of ribosomal small subunit transport from nucleus to cytoplasm|positive regulation of 40S ribosomal subunit export from nucleus|positive regulation of 30S ribosomal subunit export from nucleus|positive regulation of ribosomal small subunit export from cell nucleus|positive regulation of ribosomal small subunit export out of nucleus|positive regulation of ribosomal small subunit-nucleus export http://purl.obolibrary.org/obo/GO_2000208 GO:2000209 biolink:BiologicalProcess regulation of anoikis Any process that modulates the frequency, rate or extent of anoikis. go-plus.json regulation of suspension induced apoptosis|regulation of detachment induced cell death http://purl.obolibrary.org/obo/GO_2000209 GO:2000200 biolink:BiologicalProcess regulation of ribosomal subunit export from nucleus Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus. go-plus.json regulation of ribosomal subunit transport from nucleus to cytoplasm|regulation of ribosomal subunit export from cell nucleus|regulation of ribosomal subunit export out of nucleus|regulation of ribosome export from nucleus|regulation of ribosomal subunit-nucleus export http://purl.obolibrary.org/obo/GO_2000200 GO:2000201 biolink:BiologicalProcess negative regulation of ribosomal subunit export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus. go-plus.json negative regulation of ribosome export from nucleus|negative regulation of ribosomal subunit transport from nucleus to cytoplasm|negative regulation of ribosomal subunit-nucleus export|negative regulation of ribosomal subunit export out of nucleus|negative regulation of ribosomal subunit export from cell nucleus http://purl.obolibrary.org/obo/GO_2000201 GO:2000202 biolink:BiologicalProcess positive regulation of ribosomal subunit export from nucleus Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus. go-plus.json positive regulation of ribosomal subunit export from cell nucleus|positive regulation of ribosomal subunit transport from nucleus to cytoplasm|positive regulation of ribosome export from nucleus|positive regulation of ribosomal subunit-nucleus export|positive regulation of ribosomal subunit export out of nucleus http://purl.obolibrary.org/obo/GO_2000202 GO:2000214 biolink:BiologicalProcess regulation of proline metabolic process Any process that modulates the frequency, rate or extent of proline metabolic process. go-plus.json regulation of proline metabolism http://purl.obolibrary.org/obo/GO_2000214 GO:2000215 biolink:BiologicalProcess negative regulation of proline metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process. go-plus.json negative regulation of proline metabolism http://purl.obolibrary.org/obo/GO_2000215 GO:2000216 biolink:BiologicalProcess positive regulation of proline metabolic process Any process that activates or increases the frequency, rate or extent of proline metabolic process. go-plus.json positive regulation of proline metabolism http://purl.obolibrary.org/obo/GO_2000216 GO:2000217 biolink:BiologicalProcess regulation of invasive growth in response to glucose limitation Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation. go-plus.json regulation of colony morphology http://purl.obolibrary.org/obo/GO_2000217 GO:2000218 biolink:BiologicalProcess negative regulation of invasive growth in response to glucose limitation Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation. go-plus.json negative regulation of colony morphology http://purl.obolibrary.org/obo/GO_2000218 GO:2000219 biolink:BiologicalProcess positive regulation of invasive growth in response to glucose limitation Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation. go-plus.json positive regulation of colony morphology http://purl.obolibrary.org/obo/GO_2000219 CHEBI:31529 biolink:ChemicalSubstance ecgonine methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_31529 GO:2000210 biolink:BiologicalProcess positive regulation of anoikis Any process that activates or increases the frequency, rate or extent of anoikis. go-plus.json positive regulation of detachment induced cell death|positive regulation of suspension induced apoptosis http://purl.obolibrary.org/obo/GO_2000210 GO:2000211 biolink:BiologicalProcess regulation of glutamate metabolic process Any process that modulates the frequency, rate or extent of glutamate metabolic process. go-plus.json regulation of glutamic acid metabolism|regulation of glutamic acid metabolic process|regulation of glutamate metabolism http://purl.obolibrary.org/obo/GO_2000211 GO:2000212 biolink:BiologicalProcess negative regulation of glutamate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. go-plus.json negative regulation of glutamate metabolism|negative regulation of glutamic acid metabolic process|negative regulation of glutamic acid metabolism http://purl.obolibrary.org/obo/GO_2000212 GO:2000213 biolink:BiologicalProcess positive regulation of glutamate metabolic process Any process that activates or increases the frequency, rate or extent of glutamate metabolic process. go-plus.json positive regulation of glutamate metabolism|positive regulation of glutamic acid metabolic process|positive regulation of glutamic acid metabolism http://purl.obolibrary.org/obo/GO_2000213 GO:0002067 biolink:BiologicalProcess glandular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. go-plus.json http://purl.obolibrary.org/obo/GO_0002067 GO:0002068 biolink:BiologicalProcess glandular epithelial cell development The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. go-plus.json http://purl.obolibrary.org/obo/GO_0002068 GO:0002069 biolink:BiologicalProcess columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. go-plus.json http://purl.obolibrary.org/obo/GO_0002069 GO:0002063 biolink:BiologicalProcess chondrocyte development The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. go-plus.json http://purl.obolibrary.org/obo/GO_0002063 GO:0002064 biolink:BiologicalProcess epithelial cell development The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. go-plus.json http://purl.obolibrary.org/obo/GO_0002064 GO:0002065 biolink:BiologicalProcess columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. go-plus.json http://purl.obolibrary.org/obo/GO_0002065 GO:0002066 biolink:BiologicalProcess columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. go-plus.json http://purl.obolibrary.org/obo/GO_0002066 GO:0002060 biolink:MolecularActivity purine nucleobase binding Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton. go-plus.json purine base binding|purine binding http://purl.obolibrary.org/obo/GO_0002060 GO:0002061 biolink:MolecularActivity pyrimidine nucleobase binding Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton. go-plus.json pyrimidine base binding|pyrimidine binding|1,3-diazine binding http://purl.obolibrary.org/obo/GO_0002061 GO:0002062 biolink:BiologicalProcess chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_0002062 NCBITaxon:147429 biolink:OrganismalEntity Andropogoneae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147429 NCBITaxon:147428 biolink:OrganismalEntity Paniceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_147428 GO:0002078 biolink:BiologicalProcess membrane fusion involved in acrosome reaction The fusion of the plasma membrane of the sperm with the outer acrosomal membrane. go-plus.json membrane fusion involved in the acrosomal reaction http://purl.obolibrary.org/obo/GO_0002078 GO:0002079 biolink:CellularComponent inner acrosomal membrane The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0002079 GO:0002074 biolink:BiologicalProcess extraocular skeletal muscle development The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0002074 GO:0002075 biolink:BiologicalProcess somitomeric trunk muscle development The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0002075 GO:0002076 biolink:BiologicalProcess osteoblast development The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone. go-plus.json http://purl.obolibrary.org/obo/GO_0002076 GO:0002077 biolink:BiologicalProcess acrosome matrix dispersal The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0002077 GO:0002070 biolink:BiologicalProcess epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. go-plus.json http://purl.obolibrary.org/obo/GO_0002070 GO:0002071 biolink:BiologicalProcess glandular epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. go-plus.json http://purl.obolibrary.org/obo/GO_0002071 GO:0002072 biolink:BiologicalProcess optic cup morphogenesis involved in camera-type eye development The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. go-plus.json optic cup morphogenesis involved in camera-style eye development http://purl.obolibrary.org/obo/GO_0002072 GO:0002073 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002073 GO:0002080 biolink:CellularComponent acrosomal membrane The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization. go-plus.json http://purl.obolibrary.org/obo/GO_0002080 GO:0002049 biolink:BiologicalProcess pyoverdine biosynthetic process The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine. go-plus.json http://purl.obolibrary.org/obo/GO_0002049 GO:0002045 biolink:BiologicalProcess regulation of cell adhesion involved in intussusceptive angiogenesis The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0002045 GO:0002046 biolink:MolecularActivity opsin binding Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception. go-plus.json metarhodopsin binding http://purl.obolibrary.org/obo/GO_0002046 GO:0002047 biolink:BiologicalProcess phenazine biosynthetic process The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring. go-plus.json dibenzopyrazine biosynthesis|dibenzopyrazine biosynthetic process|acridizine biosynthetic process|acridizine biosynthesis|azophenylene biosynthetic process|azophenylene biosynthesis|dibenzo-p-diazine biosynthesis|dibenzo-p-diazine biosynthetic process http://purl.obolibrary.org/obo/GO_0002047 GO:0002048 biolink:BiologicalProcess pyoverdine metabolic process The chemical reactions and pathways involving the siderochrome pyoverdine. go-plus.json pyoverdine metabolism http://purl.obolibrary.org/obo/GO_0002048 GO:0002041 biolink:BiologicalProcess intussusceptive angiogenesis The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars. go-plus.json http://purl.obolibrary.org/obo/GO_0002041 GO:0002042 biolink:BiologicalProcess cell migration involved in sprouting angiogenesis The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0002042 GO:0002043 biolink:BiologicalProcess blood vessel endothelial cell proliferation involved in sprouting angiogenesis The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis. go-plus.json blood vessel endothelial cell proliferation during sprouting angiogenesis http://purl.obolibrary.org/obo/GO_0002043 GO:0002044 biolink:BiologicalProcess blood vessel endothelial cell migration involved in intussusceptive angiogenesis The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0002044 GO:0002040 biolink:BiologicalProcess sprouting angiogenesis The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation. go-plus.json http://purl.obolibrary.org/obo/GO_0002040 GO:0016686 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016686 GO:0016687 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016687 GO:0016688 biolink:MolecularActivity L-ascorbate peroxidase activity Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O. EC:1.11.1.11|RHEA:22996|MetaCyc:L-ASCORBATE-PEROXIDASE-RXN go-plus.json ascorbate peroxidase activity|L-ascorbate:hydrogen-peroxide oxidoreductase activity|ascorbic acid peroxidase activity|L-ascorbic acid peroxidase activity|L-ascorbic acid-specific peroxidase activity http://purl.obolibrary.org/obo/GO_0016688 GO:0016689 biolink:MolecularActivity manganese peroxidase activity Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O. EC:1.11.1.13|MetaCyc:MANGANESE-PEROXIDASE-RXN|RHEA:22776 go-plus.json peroxidase-M2|Mn(II):hydrogen-peroxide oxidoreductase activity|Mn-dependent (NADH-oxidizing) peroxidase activity|Mn-dependent peroxidase activity http://purl.obolibrary.org/obo/GO_0016689 GO:0016682 biolink:MolecularActivity oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen. EC:1.10.3.- go-plus.json laccase activity http://purl.obolibrary.org/obo/GO_0016682 GO:0016683 biolink:MolecularActivity obsolete oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen. go-plus.json oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors http://purl.obolibrary.org/obo/GO_0016683 GO:0016684 biolink:MolecularActivity oxidoreductase activity, acting on peroxide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor. EC:1.11.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016684 GO:0016685 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016685 GO:0016680 biolink:MolecularActivity oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.10.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016680 GO:0016681 biolink:MolecularActivity obsolete oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome. EC:1.10.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016681 GO:0002056 biolink:MolecularActivity cytosine binding Binding to cytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0002056 GO:0002057 biolink:MolecularActivity guanine binding Binding to guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0002057 GO:0002058 biolink:MolecularActivity uracil binding Binding to uracil. go-plus.json http://purl.obolibrary.org/obo/GO_0002058 NCBITaxon:1477431 biolink:OrganismalEntity Streptomyces albidoflavus group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1477431 GO:0002059 biolink:MolecularActivity thymine binding Binding to thymine. go-plus.json http://purl.obolibrary.org/obo/GO_0002059 GO:0002052 biolink:BiologicalProcess positive regulation of neuroblast proliferation Any process that activates or increases the rate of neuroblast proliferation. go-plus.json upregulation of neuroblast proliferation|stimulation of neuroblast proliferation|up-regulation of neuroblast proliferation|activation of neuroblast proliferation|up regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_0002052 GO:0002053 biolink:BiologicalProcess positive regulation of mesenchymal cell proliferation The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. go-plus.json upregulation of mesenchymal cell proliferation|stimulation of mesenchymal cell proliferation|up-regulation of mesenchymal cell proliferation|activation of mesenchymal cell proliferation|up regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0002053 GO:0002054 biolink:MolecularActivity nucleobase binding Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases. go-plus.json http://purl.obolibrary.org/obo/GO_0002054 goslim_pir GO:0002055 biolink:MolecularActivity adenine binding Binding to adenine, a purine base. go-plus.json 6-aminopurine binding http://purl.obolibrary.org/obo/GO_0002055 GO:0002050 biolink:BiologicalProcess pyoverdine catabolic process The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine. go-plus.json http://purl.obolibrary.org/obo/GO_0002050 GO:0002051 biolink:BiologicalProcess osteoblast fate commitment The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. go-plus.json http://purl.obolibrary.org/obo/GO_0002051 GO:0016697 biolink:MolecularActivity oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome. EC:1.12.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016697 GO:0016698 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016698 GO:0016699 biolink:MolecularActivity oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein. EC:1.12.7.- go-plus.json oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0016699 GO:0016693 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016693 GO:0016694 biolink:MolecularActivity obsolete bacterial catalase-peroxidase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json bacterial catalase-peroxidase activity http://purl.obolibrary.org/obo/GO_0016694 GO:0016695 biolink:MolecularActivity oxidoreductase activity, acting on hydrogen as donor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor. EC:1.12.-.- go-plus.json oxidoreductase activity, acting on hydrogen as donor, other acceptors http://purl.obolibrary.org/obo/GO_0016695 GO:0016696 biolink:MolecularActivity oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP. EC:1.12.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016696 GO:0016690 biolink:MolecularActivity diarylpropane peroxidase activity Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O. RHEA:30271|MetaCyc:DIARYLPROPANE-PEROXIDASE-RXN|EC:1.11.1.14 go-plus.json diarylpropane oxygenase activity|diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)|lignin peroxidase activity|LiP activity|ligninase I activity|ligninase activity|1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0016690 GO:0016691 biolink:MolecularActivity chloride peroxidase activity Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O. EC:1.11.1.10|MetaCyc:CHLORIDE-PEROXIDASE-RXN go-plus.json flavin-heme chloroperoxidase activity|haem chloroperoxidase activity|cofactor-free chloroperoxidase activity|vanadium chloroperoxidase activity|chloride:hydrogen-peroxide oxidoreductase|chloroperoxidase activity|heme chloroperoxidase activity|flavin-haem chloroperoxidase activity http://purl.obolibrary.org/obo/GO_0016691 GO:0016692 biolink:MolecularActivity NADH peroxidase activity Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+). KEGG_REACTION:R00090|EC:1.11.1.1|MetaCyc:NADH-PEROXIDASE-RXN|RHEA:18509 go-plus.json diphosphopyridine nucleotide peroxidase activity|nicotinamide adenine dinucleotide peroxidase activity|NAD peroxidase activity|NADH:hydrogen-peroxide oxidoreductase activity|NADH-peroxidase activity|DPNH peroxidase activity http://purl.obolibrary.org/obo/GO_0016692 GO:0002027 biolink:BiologicalProcess regulation of heart rate Any process that modulates the frequency or rate of heart contraction. go-plus.json regulation of rate of heart contraction|cardiac chronotropy|regulation of heart contraction rate http://purl.obolibrary.org/obo/GO_0002027 GO:0002028 biolink:BiologicalProcess regulation of sodium ion transport Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of Na+ transport|regulation of sodium transport http://purl.obolibrary.org/obo/GO_0002028 GO:0002029 biolink:BiologicalProcess desensitization of G protein-coupled receptor signaling pathway The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway. go-plus.json desensitization of G-protein coupled receptor protein signaling pathway|desensitisation of G-protein coupled receptor protein signalling pathway http://purl.obolibrary.org/obo/GO_0002029 GO:0002023 biolink:BiologicalProcess reduction of food intake in response to dietary excess An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients. go-plus.json http://purl.obolibrary.org/obo/GO_0002023 GO:0002024 biolink:BiologicalProcess diet induced thermogenesis The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0002024 GO:0002025 biolink:BiologicalProcess norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change. go-plus.json vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|noradrenaline-adrenaline vasodilation involved in regulation of blood pressure|norepinephrine-epinephrine vasodilation during blood pressure regulation http://purl.obolibrary.org/obo/GO_0002025 GO:0002026 biolink:BiologicalProcess regulation of the force of heart contraction Any process that modulates the extent of heart contraction, changing the force with which blood is propelled. go-plus.json heart inotropy|cardiac inotropy http://purl.obolibrary.org/obo/GO_0002026 GO:2000269 biolink:BiologicalProcess regulation of fibroblast apoptotic process Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. go-plus.json regulation of fibroblast apoptosis http://purl.obolibrary.org/obo/GO_2000269 GO:0002020 biolink:MolecularActivity protease binding Binding to a protease or a peptidase. Reactome:R-HSA-1297354 go-plus.json http://purl.obolibrary.org/obo/GO_0002020 GO:0002021 biolink:BiologicalProcess response to dietary excess The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure. go-plus.json http://purl.obolibrary.org/obo/GO_0002021 GO:0002022 biolink:BiologicalProcess detection of dietary excess The neurological process in which the brain senses excessive caloric intake. go-plus.json http://purl.obolibrary.org/obo/GO_0002022 GO:0016668 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.8.1.- go-plus.json oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016668 GO:2000261 biolink:BiologicalProcess negative regulation of blood coagulation, common pathway Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000261 GO:2000262 biolink:BiologicalProcess positive regulation of blood coagulation, common pathway Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000262 GO:0016669 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome. EC:1.8.2.- go-plus.json oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor http://purl.obolibrary.org/obo/GO_0016669 GO:2000263 biolink:BiologicalProcess regulation of blood coagulation, extrinsic pathway Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000263 GO:2000264 biolink:BiologicalProcess negative regulation of blood coagulation, extrinsic pathway Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000264 GO:0016664 biolink:MolecularActivity oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.7.7.- go-plus.json oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0016664 GO:2000265 biolink:BiologicalProcess positive regulation of blood coagulation, extrinsic pathway Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000265 GO:0016665 biolink:MolecularActivity obsolete oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP. go-plus.json oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors http://purl.obolibrary.org/obo/GO_0016665 GO:2000266 biolink:BiologicalProcess regulation of blood coagulation, intrinsic pathway Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000266 GO:2000267 biolink:BiologicalProcess negative regulation of blood coagulation, intrinsic pathway Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000267 GO:0016666 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016666 GO:0016667 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.8.-.-|Reactome:R-HSA-2213240 go-plus.json oxidoreductase activity, acting on sulfur group of donors, other acceptors|oxidoreductase activity, acting on sulphur group of donors http://purl.obolibrary.org/obo/GO_0016667 GO:2000268 biolink:BiologicalProcess positive regulation of blood coagulation, intrinsic pathway Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000268 GO:0016660 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016660 GO:0016661 biolink:MolecularActivity oxidoreductase activity, acting on other nitrogenous compounds as donors Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.7.-.- go-plus.json oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors http://purl.obolibrary.org/obo/GO_0016661 GO:0016662 biolink:MolecularActivity oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome. EC:1.7.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016662 GO:0016663 biolink:MolecularActivity oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen. EC:1.7.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016663 GO:2000260 biolink:BiologicalProcess regulation of blood coagulation, common pathway Any process that modulates the frequency, rate or extent of blood coagulation, common pathway. go-plus.json http://purl.obolibrary.org/obo/GO_2000260 GO:0002038 biolink:BiologicalProcess positive regulation of L-glutamate import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell. go-plus.json upregulation of L-glutamate uptake|up-regulation of L-glutamate import|activation of L-glutamate import|activation of L-glutamate uptake|positive regulation of L-glutamate import|up-regulation of L-glutamate uptake|upregulation of L-glutamate transport|activation of L-glutamate transport|up regulation of L-glutamate import|stimulation of L-glutamate transport|positive regulation of L-glutamate uptake|up regulation of L-glutamate transport|up regulation of L-glutamate uptake|positive regulation of L-glutamate transport|up-regulation of L-glutamate transport|upregulation of L-glutamate import http://purl.obolibrary.org/obo/GO_0002038 GO:0002039 biolink:MolecularActivity p53 binding Binding to one of the p53 family of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0002039 GO:0002034 biolink:BiologicalProcess maintenance of blood vessel diameter homeostasis by renin-angiotensin The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system. go-plus.json regulation of blood vessel size by renin-angiotensin|regulation of blood vessel diameter by renin-angiotensin|renin-angiotensin regulation of blood vessel size http://purl.obolibrary.org/obo/GO_0002034 GO:0002035 biolink:BiologicalProcess brain renin-angiotensin system The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system. go-plus.json http://purl.obolibrary.org/obo/GO_0002035 GO:0002036 biolink:BiologicalProcess regulation of L-glutamate import across plasma membrane Any process that modulates the frequency, rate or extent of L-glutamate import into a cell. go-plus.json regulation of L-glutamate transport|regulation of L-glutamate import|regulation of L-glutamate uptake http://purl.obolibrary.org/obo/GO_0002036 GO:0002037 biolink:BiologicalProcess negative regulation of L-glutamate import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell. go-plus.json down regulation of L-glutamate uptake|negative regulation of L-glutamate import|down-regulation of L-glutamate import|down regulation of L-glutamate transport|regulation of L-glutamate import|negative regulation of L-glutamate uptake|down-regulation of L-glutamate uptake|downregulation of L-glutamate transport|downregulation of L-glutamate import|down regulation of L-glutamate import|inhibition of L-glutamate transport|inhibition of L-glutamate import|inhibition of L-glutamate uptake|downregulation of L-glutamate uptake|down-regulation of L-glutamate transport|negative regulation of L-glutamate transport http://purl.obolibrary.org/obo/GO_0002037 GO:0002030 biolink:BiologicalProcess inhibitory G protein-coupled receptor phosphorylation The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site. go-plus.json inhibitory G-protein coupled receptor phosphorylation http://purl.obolibrary.org/obo/GO_0002030 GO:0002031 biolink:BiologicalProcess G protein-coupled receptor internalization The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle. go-plus.json G-protein coupled receptor internalization http://purl.obolibrary.org/obo/GO_0002031 GO:0002032 biolink:BiologicalProcess desensitization of G protein-coupled receptor signaling pathway by arrestin The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins. go-plus.json arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway|arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway|desensitization of G-protein coupled receptor protein signaling pathway by arrestin|arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway http://purl.obolibrary.org/obo/GO_0002032 GO:0002033 biolink:BiologicalProcess angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure The process that increases the diameter of a blood vessel via the renin-angiotensin system. go-plus.json vasodilation by angiotensin involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0002033 GO:2000272 biolink:BiologicalProcess negative regulation of signaling receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. go-plus.json negative regulation of signalling receptor activity|negative regulation of receptor activity http://purl.obolibrary.org/obo/GO_2000272 GO:0016679 biolink:MolecularActivity oxidoreductase activity, acting on diphenols and related substances as donors Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.10.-.- go-plus.json oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors http://purl.obolibrary.org/obo/GO_0016679 GO:2000273 biolink:BiologicalProcess positive regulation of signaling receptor activity Any process that activates or increases the frequency, rate or extent of signaling receptor activity. go-plus.json positive regulation of signalling receptor activity http://purl.obolibrary.org/obo/GO_2000273 GO:2000274 biolink:BiologicalProcess regulation of epithelial cell migration, open tracheal system Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system. go-plus.json regulation of tracheal cell migration|regulation of tracheal epithelial cell migration http://purl.obolibrary.org/obo/GO_2000274 GO:2000275 biolink:BiologicalProcess regulation of oxidative phosphorylation uncoupler activity Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity. go-plus.json regulation of uncoupling protein activity|regulation of mitochondrial uncoupling protein activity http://purl.obolibrary.org/obo/GO_2000275 GO:0016675 biolink:MolecularActivity oxidoreductase activity, acting on a heme group of donors Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.9.-.- go-plus.json oxidoreductase activity, acting on heme group of donors, other acceptors|oxidoreductase activity, acting on haem group of donors http://purl.obolibrary.org/obo/GO_0016675 GO:2000276 biolink:BiologicalProcess negative regulation of oxidative phosphorylation uncoupler activity Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity. go-plus.json negative regulation of mitochondrial uncoupling protein activity|negative regulation of uncoupling protein activity http://purl.obolibrary.org/obo/GO_2000276 GO:0016676 biolink:MolecularActivity obsolete oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen. EC:1.9.3.- go-plus.json oxidoreductase activity, acting on haem group of donors, oxygen as acceptor http://purl.obolibrary.org/obo/GO_0016676 GO:2000277 biolink:BiologicalProcess positive regulation of oxidative phosphorylation uncoupler activity Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity. go-plus.json positive regulation of mitochondrial uncoupling protein activity|positive regulation of uncoupling protein activity http://purl.obolibrary.org/obo/GO_2000277 GO:0016677 biolink:MolecularActivity oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group. EC:1.9.6.- go-plus.json oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor http://purl.obolibrary.org/obo/GO_0016677 GO:2000278 biolink:BiologicalProcess regulation of DNA biosynthetic process Any process that modulates the frequency, rate or extent of DNA biosynthetic process. go-plus.json regulation of DNA anabolism|regulation of DNA synthesis|regulation of DNA formation|regulation of DNA biosynthesis http://purl.obolibrary.org/obo/GO_2000278 GO:0016678 biolink:MolecularActivity obsolete oxidoreductase activity, acting on heme group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen. go-plus.json oxidoreductase activity, acting on haem group of donors, other acceptors|oxidoreductase activity, acting on heme group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016678 GO:2000279 biolink:BiologicalProcess negative regulation of DNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. go-plus.json negative regulation of DNA biosynthesis|negative regulation of DNA anabolism|negative regulation of DNA synthesis|negative regulation of DNA formation http://purl.obolibrary.org/obo/GO_2000279 GO:0016671 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide. EC:1.8.4.- go-plus.json oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016671 GO:0016672 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound. EC:1.8.5.- go-plus.json oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor http://purl.obolibrary.org/obo/GO_0016672 GO:0016673 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.8.7.- go-plus.json oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0016673 GO:0016674 biolink:MolecularActivity obsolete oxidoreductase activity, acting on sulfur group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome. go-plus.json oxidoreductase activity, acting on sulfur group of donors, other acceptors|oxidoreductase activity, acting on sulphur group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016674 GO:2000270 biolink:BiologicalProcess negative regulation of fibroblast apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. go-plus.json negative regulation of fibroblast apoptosis http://purl.obolibrary.org/obo/GO_2000270 GO:2000271 biolink:BiologicalProcess positive regulation of fibroblast apoptotic process Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. go-plus.json positive regulation of fibroblast apoptosis http://purl.obolibrary.org/obo/GO_2000271 GO:0016670 biolink:MolecularActivity oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen. EC:1.8.3.- go-plus.json oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor http://purl.obolibrary.org/obo/GO_0016670 GO:0002005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002005 GO:0002006 biolink:BiologicalProcess vasoconstriction by vasopressin involved in systemic arterial blood pressure control The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream. go-plus.json vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control http://purl.obolibrary.org/obo/GO_0002006 GO:0002007 biolink:BiologicalProcess detection of hypoxic conditions in blood by chemoreceptor signaling The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. go-plus.json detection of hypoxic conditions in blood by chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0002007 GO:0002008 biolink:BiologicalProcess excitation of vasomotor center by chemoreceptor signaling The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure. go-plus.json excitation of vasomotor center by chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0002008 GO:0002001 biolink:BiologicalProcess renin secretion into blood stream The regulated release of renin into the blood stream by juxtoglomerular cells. go-plus.json renin release into blood stream http://purl.obolibrary.org/obo/GO_0002001 GO:0002002 biolink:BiologicalProcess regulation of angiotensin levels in blood The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation. go-plus.json control of blood angiotensin level|regulation of blood angiotensin level|control of angiotensin levels in blood http://purl.obolibrary.org/obo/GO_0002002 GO:0002003 biolink:BiologicalProcess angiotensin maturation The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood. go-plus.json angiotensin catabolic process in blood http://purl.obolibrary.org/obo/GO_0002003 GO:0002004 biolink:BiologicalProcess secretion of vasopressin involved in fast regulation of systemic arterial blood pressure The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure. go-plus.json secretion of vasopressin during fast control of blood pressure|secretion of vasopressin during fast regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0002004 GO:0002000 biolink:BiologicalProcess detection of renal blood flow The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0002000 GO:2000283 biolink:BiologicalProcess negative regulation of cellular amino acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process. go-plus.json negative regulation of cellular amino acid anabolism|negative regulation of amino acid biosynthetic process|negative regulation of cellular amino acid synthesis|negative regulation of cellular amino acid formation|negative regulation of cellular amino acid biosynthesis http://purl.obolibrary.org/obo/GO_2000283 GO:0016646 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.5.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016646 GO:2000284 biolink:BiologicalProcess positive regulation of cellular amino acid biosynthetic process Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. go-plus.json positive regulation of cellular amino acid biosynthesis|positive regulation of cellular amino acid synthesis|positive regulation of cellular amino acid formation|positive regulation of amino acid biosynthetic process|positive regulation of cellular amino acid anabolism http://purl.obolibrary.org/obo/GO_2000284 GO:0016647 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen. EC:1.5.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016647 GO:0016648 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide. EC:1.5.4.- go-plus.json oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016648 GO:2000285 biolink:BiologicalProcess obsolete negative regulation of regulation of excitatory postsynaptic membrane potential OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential. go-plus.json negative regulation of regulation of excitatory postsynaptic membrane potential|negative regulation of EPSP http://purl.obolibrary.org/obo/GO_2000285 GO:0016649 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound. EC:1.5.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0016649 GO:2000286 biolink:BiologicalProcess receptor internalization involved in canonical Wnt signaling pathway A receptor internalization process that contributes to canonical Wnt signaling pathway. go-plus.json receptor internalization involved in canonical Wnt-activated signaling pathway|receptor internalization involved in canonical Wnt receptor signaling pathway|receptor internalization involved in frizzled-1 receptor signaling pathway|receptor internalization involved in Wnt receptor signaling pathway through beta-catenin|receptor internalization involved in canonical Wnt receptor signalling pathway|receptor internalization involved in Wnt receptor signalling pathway through beta-catenin|receptor internalization involved in Wnt receptor signaling pathway via beta-catenin http://purl.obolibrary.org/obo/GO_2000286 GO:0016642 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group. EC:1.4.4.- go-plus.json oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016642 GO:2000287 biolink:BiologicalProcess positive regulation of myotome development Any process that activates or increases the frequency, rate or extent of myotome development. go-plus.json http://purl.obolibrary.org/obo/GO_2000287 GO:0016643 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.4.7.- go-plus.json oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0016643 GO:2000288 biolink:BiologicalProcess positive regulation of myoblast proliferation Any process that activates or increases the frequency, rate or extent of myoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000288 GO:2000289 biolink:BiologicalProcess regulation of photoreceptor cell axon guidance Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance. go-plus.json regulation of photoreceptor cell axon pathfinding http://purl.obolibrary.org/obo/GO_2000289 GO:0016644 biolink:MolecularActivity obsolete oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen. go-plus.json oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016644 GO:0016645 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.5.-.- go-plus.json oxidoreductase activity, acting on the CH-NH group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016645 GO:0016640 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule. EC:1.4.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016640 GO:0016641 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule. EC:1.4.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016641 GO:0002009 biolink:BiologicalProcess morphogenesis of an epithelium The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. go-plus.json epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0002009 GO:2000280 biolink:BiologicalProcess regulation of root development Any process that modulates the frequency, rate or extent of root development. go-plus.json http://purl.obolibrary.org/obo/GO_2000280 GO:2000281 biolink:BiologicalProcess regulation of histone H3-T3 phosphorylation Any process that modulates the frequency, rate or extent of histone H3-T3 phosphorylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000281 GO:2000282 biolink:BiologicalProcess regulation of cellular amino acid biosynthetic process Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. go-plus.json regulation of cellular amino acid biosynthesis|regulation of cellular amino acid anabolism|regulation of amino acid biosynthetic process|regulation of cellular amino acid synthesis|regulation of cellular amino acid formation http://purl.obolibrary.org/obo/GO_2000282 GO:0002016 biolink:BiologicalProcess regulation of blood volume by renin-angiotensin The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood. go-plus.json renin-angiotensin regulation of blood volume|renin-angiotensin control of body fluid levels http://purl.obolibrary.org/obo/GO_0002016 GO:0002017 biolink:BiologicalProcess regulation of blood volume by renal aldosterone The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume. go-plus.json renal regulation of blood volume by aldosterone|aldosterone mediated regulation of blood volume|aldosterone mediated control of body fluids http://purl.obolibrary.org/obo/GO_0002017 GO:0002018 biolink:BiologicalProcess renin-angiotensin regulation of aldosterone production The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone. go-plus.json renin-angiotensin control of aldosterone production http://purl.obolibrary.org/obo/GO_0002018 GO:0002019 biolink:BiologicalProcess regulation of renal output by angiotensin The process in which angiotensin directly modulates the rate of urine output by the kidney. go-plus.json angiotensin-mediated regulation of renal output|angiotensin mediated control of renal output|angiotensin mediated regulation of renal output http://purl.obolibrary.org/obo/GO_0002019 GO:0002012 biolink:BiologicalProcess vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure. go-plus.json http://purl.obolibrary.org/obo/GO_0002012 GO:0002013 biolink:BiologicalProcess detection of carbon dioxide by vasomotor center The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0002013 GO:0002014 biolink:BiologicalProcess vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0002014 GO:0002015 biolink:BiologicalProcess regulation of systemic arterial blood pressure by atrial baroreceptor feedback A process that controls blood pressure by sensing the amount of stretch occurring in the atria. go-plus.json atrial control of blood pressure|atrial low pressure baroreceptor regulation of blood pressure|atrial baroreceptor regulation of systemic arterial blood pressure|atrial reflex http://purl.obolibrary.org/obo/GO_0002015 GO:0002010 biolink:BiologicalProcess excitation of vasomotor center by baroreceptor signaling The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure. go-plus.json excitation of vasomotor center by baroreceptor signalling http://purl.obolibrary.org/obo/GO_0002010 GO:0002011 biolink:BiologicalProcess morphogenesis of an epithelial sheet The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0002011 NCBITaxon:436308 biolink:OrganismalEntity Nitrosopumilus maritimus SCM1 go-plus.json Nitrosopumilus maritimus strain SCM1|Seattle Aquarium strain SCM1|Nitrosopumilus maritimus str. SCM1 http://purl.obolibrary.org/obo/NCBITaxon_436308 GO:0016657 biolink:MolecularActivity oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group. EC:1.6.6.- go-plus.json oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor http://purl.obolibrary.org/obo/GO_0016657 GO:2000294 biolink:BiologicalProcess positive regulation of defecation Any process that activates or increases the frequency, rate or extent of defecation. go-plus.json http://purl.obolibrary.org/obo/GO_2000294 GO:2000295 biolink:BiologicalProcess regulation of hydrogen peroxide catabolic process Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process. go-plus.json regulation of hydrogen peroxide catabolism|regulation of H2O2 catabolic process|regulation of hydrogen peroxide removal|regulation of hydrogen peroxide degradation|regulation of hydrogen peroxide scavenging|regulation of hydrogen peroxide breakdown|regulation of detoxification of H2O2|regulation of H2O2 scavenging|regulation of detoxification of hydrogen peroxide http://purl.obolibrary.org/obo/GO_2000295 GO:0016658 biolink:MolecularActivity obsolete oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor http://purl.obolibrary.org/obo/GO_0016658 GO:2000296 biolink:BiologicalProcess negative regulation of hydrogen peroxide catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process. go-plus.json negative regulation of hydrogen peroxide scavenging|negative regulation of H2O2 scavenging|negative regulation of detoxification of hydrogen peroxide|negative regulation of detoxification of H2O2|negative regulation of hydrogen peroxide removal|negative regulation of hydrogen peroxide degradation|negative regulation of hydrogen peroxide catabolism|negative regulation of H2O2 catabolic process|negative regulation of hydrogen peroxide breakdown http://purl.obolibrary.org/obo/GO_2000296 GO:0016659 biolink:MolecularActivity obsolete oxidoreductase activity, acting on NADH or NADPH, other acceptor OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen. go-plus.json oxidoreductase activity, acting on NADH or NADPH, other acceptor http://purl.obolibrary.org/obo/GO_0016659 GO:2000297 biolink:BiologicalProcess negative regulation of synapse maturation Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation. go-plus.json negative regulation of synaptic maturation http://purl.obolibrary.org/obo/GO_2000297 GO:2000298 biolink:BiologicalProcess regulation of Rho-dependent protein serine/threonine kinase activity Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity. go-plus.json regulation of Rho-associated protein kinase activity|regulation of ROCK kinase activity http://purl.obolibrary.org/obo/GO_2000298 GO:0016653 biolink:MolecularActivity oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein. EC:1.6.2.- go-plus.json oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor|oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor http://purl.obolibrary.org/obo/GO_0016653 GO:2000299 biolink:BiologicalProcess negative regulation of Rho-dependent protein serine/threonine kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity. go-plus.json negative regulation of ROCK kinase activity|negative regulation of Rho-associated protein kinase activity http://purl.obolibrary.org/obo/GO_2000299 GO:0016654 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016654 GO:0016655 biolink:MolecularActivity oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. EC:1.6.5.- go-plus.json oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor http://purl.obolibrary.org/obo/GO_0016655 GO:0016656 biolink:MolecularActivity monodehydroascorbate reductase (NADH) activity Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate. MetaCyc:1.6.5.4-RXN|EC:1.6.5.4|RHEA:14581 go-plus.json MDHA|ascorbate free radical reductase activity|semidehydroascorbate reductase activity|AFR|NADH:AFR oxidoreductase activity|SDA reductase activity|MDAsA reductase (NADPH)|ascorbate free-radical reductase activity|NADH:ascorbate radical oxidoreductase activity|NADH:monodehydroascorbate oxidoreductase activity|monodehydroascorbate reductase activity|NADH-semidehydroascorbate oxidoreductase activity|ascorbic free radical reductase activity|NADH:semidehydroascorbic acid oxidoreductase activity|AFR-reductase activity http://purl.obolibrary.org/obo/GO_0016656 GO:0016650 biolink:MolecularActivity obsolete oxidoreductase activity, acting on the CH-NH group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin. go-plus.json oxidoreductase activity, acting on the CH-NH group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016650 GO:0016651 biolink:MolecularActivity oxidoreductase activity, acting on NAD(P)H Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Reactome:R-HSA-109343|EC:1.6.-.-|Reactome:R-HSA-8956458 go-plus.json oxidoreductase activity, acting on NADH or NADPH|NAD(P)H dehydrogenase|oxidoreductase activity, acting on NADH or NADPH, other acceptor http://purl.obolibrary.org/obo/GO_0016651 GO:0016652 biolink:MolecularActivity oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP. EC:1.6.1.- go-plus.json oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor http://purl.obolibrary.org/obo/GO_0016652 GO:2000290 biolink:BiologicalProcess regulation of myotome development Any process that modulates the frequency, rate or extent of myotome development. go-plus.json http://purl.obolibrary.org/obo/GO_2000290 CHEBI:55552 biolink:ChemicalSubstance thymidine 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55552 GO:2000291 biolink:BiologicalProcess regulation of myoblast proliferation Any process that modulates the frequency, rate or extent of myoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000291 GO:2000292 biolink:BiologicalProcess regulation of defecation Any process that modulates the frequency, rate or extent of defecation. go-plus.json http://purl.obolibrary.org/obo/GO_2000292 CHEBI:55550 biolink:ChemicalSubstance dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_55550 chebi_ph7_3 GO:2000293 biolink:BiologicalProcess negative regulation of defecation Any process that stops, prevents or reduces the frequency, rate or extent of defecation. go-plus.json http://purl.obolibrary.org/obo/GO_2000293 CHEBI:55551 biolink:ChemicalSubstance dalnigrein go-plus.json http://purl.obolibrary.org/obo/CHEBI_55551 GO:0099137 biolink:BiologicalProcess altruistic, chimeric, non-reproductive fruiting body development Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell. go-plus.json fully co-operative, chimeric, non-reproductive fruiting body development http://purl.obolibrary.org/obo/GO_0099137 GO:2000904 biolink:BiologicalProcess regulation of starch metabolic process Any process that modulates the frequency, rate or extent of starch metabolic process. go-plus.json regulation of starch metabolism http://purl.obolibrary.org/obo/GO_2000904 GO:0110016 biolink:CellularComponent B-WICH complex A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself. go-plus.json http://purl.obolibrary.org/obo/GO_0110016 GO:2000905 biolink:BiologicalProcess negative regulation of starch metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process. go-plus.json negative regulation of starch metabolism http://purl.obolibrary.org/obo/GO_2000905 GO:0099138 biolink:BiologicalProcess altruistic, chimeric sorocarp development Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell. go-plus.json fully co-operative, chimeric sorocarp development http://purl.obolibrary.org/obo/GO_0099138 GO:0110017 biolink:BiologicalProcess cap-independent translational initiation of linear mRNA The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation. go-plus.json http://purl.obolibrary.org/obo/GO_0110017 GO:2000906 biolink:BiologicalProcess positive regulation of starch metabolic process Any process that activates or increases the frequency, rate or extent of starch metabolic process. go-plus.json positive regulation of starch metabolism http://purl.obolibrary.org/obo/GO_2000906 GO:0099135 biolink:BiologicalProcess chimeric colonial development Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype. go-plus.json http://purl.obolibrary.org/obo/GO_0099135 gocheck_do_not_manually_annotate GO:0110014 biolink:BiologicalProcess negative regulation of aggregation involved in sorocarp development Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. go-plus.json http://purl.obolibrary.org/obo/GO_0110014 GO:0099136 biolink:BiologicalProcess chimeric non-reproductive fruiting body development Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes. go-plus.json http://purl.obolibrary.org/obo/GO_0099136 gocheck_do_not_manually_annotate GO:2000907 biolink:BiologicalProcess negative regulation of glucomannan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process. go-plus.json negative regulation of glucomannan catabolism http://purl.obolibrary.org/obo/GO_2000907 GO:0110015 biolink:BiologicalProcess positive regulation of elastin catabolic process Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. go-plus.json http://purl.obolibrary.org/obo/GO_0110015 GO:0110012 biolink:BiologicalProcess protein localization to P-body Any process in which a protein is transported to, or maintained at, a P-body. go-plus.json protein localization to cytoplasmic mRNA processing body|protein localization to P body|protein localisation to P-body http://purl.obolibrary.org/obo/GO_0110012 GO:0099133 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099133 GO:2000908 biolink:BiologicalProcess positive regulation of glucomannan catabolic process Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process. go-plus.json positive regulation of glucomannan catabolism http://purl.obolibrary.org/obo/GO_2000908 GO:2000909 biolink:BiologicalProcess regulation of sterol import Any process that modulates the frequency, rate or extent of sterol import. go-plus.json regulation of sterol influx|regulation of sterol uptake http://purl.obolibrary.org/obo/GO_2000909 GO:0110013 biolink:BiologicalProcess positive regulation of aggregation involved in sorocarp development Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. go-plus.json http://purl.obolibrary.org/obo/GO_0110013 GO:0099134 biolink:BiologicalProcess chimeric sorocarp development Development of a sorocarp formed by aggregation of cells with different genotypes. go-plus.json http://purl.obolibrary.org/obo/GO_0099134 gocheck_do_not_manually_annotate GO:0099131 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099131 GO:0110010 biolink:BiologicalProcess basolateral protein secretion The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base. go-plus.json http://purl.obolibrary.org/obo/GO_0110010 GO:0110011 biolink:BiologicalProcess regulation of basement membrane organization Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0110011 GO:0099132 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099132 GO:0099130 biolink:MolecularActivity estrogen binding Binding to an estrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0099130 GO:2000900 biolink:BiologicalProcess cyclodextrin metabolic process The chemical reactions and pathways involving a cyclodextrin. go-plus.json cyclodextrin metabolism http://purl.obolibrary.org/obo/GO_2000900 GO:2000901 biolink:BiologicalProcess cyclodextrin catabolic process The chemical reactions and pathways resulting in the breakdown of a cyclodextrin. go-plus.json cyclodextrin catabolism http://purl.obolibrary.org/obo/GO_2000901 GO:2000902 biolink:BiologicalProcess cellooligosaccharide metabolic process The chemical reactions and pathways involving a cellooligosaccharide. go-plus.json cellooligosaccharide metabolism http://purl.obolibrary.org/obo/GO_2000902 CHEBI:16739 biolink:ChemicalSubstance 2-furoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16739 chebi_ph7_3 GO:2000903 biolink:BiologicalProcess cellooligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide. go-plus.json cellooligosaccharide catabolism http://purl.obolibrary.org/obo/GO_2000903 NCBITaxon:28983 biolink:OrganismalEntity Sclerotiniaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_28983 CHEBI:16737 biolink:ChemicalSubstance creatinine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16737 chebi_ph7_3 CHEBI:16738 biolink:ChemicalSubstance 2,4-dichlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16738 chebi_ph7_3 CHEBI:16735 biolink:ChemicalSubstance 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-6-O-sulfo-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16735 GO:0051191 biolink:BiologicalProcess prosthetic group biosynthetic process The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. go-plus.json coenzyme and prosthetic group biosynthesis|coenzyme and prosthetic group biosynthetic process|prosthetic group anabolism|prosthetic group synthesis|prosthetic group formation|prosthetic group biosynthesis http://purl.obolibrary.org/obo/GO_0051191 CHEBI:16733 biolink:ChemicalSubstance D-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16733 GO:0051192 biolink:MolecularActivity prosthetic group binding Binding to a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0051192 CHEBI:16734 biolink:ChemicalSubstance N-acetyl-D-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_16734 CHEBI:41701 biolink:ChemicalSubstance (2S)-amino[(4R)-2-iminohexahydropyrimidin-4-yl]acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41701 CHEBI:16731 biolink:ChemicalSubstance (E)-cinnamaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16731 chebi_ph7_3 GO:0075160 biolink:BiologicalProcess obsolete positive regulation of G-protein alpha subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075160 GO:0075161 biolink:BiologicalProcess obsolete negative regulation of G-protein alpha subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075161 GO:0051190 biolink:BiologicalProcess prosthetic group catabolic process The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. go-plus.json coenzyme and prosthetic group catabolism|prosthetic group breakdown|coenzyme and prosthetic group catabolic process|prosthetic group catabolism|prosthetic group degradation http://purl.obolibrary.org/obo/GO_0051190 CHEBI:16732 biolink:ChemicalSubstance CDP-ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16732 GO:0075162 biolink:BiologicalProcess obsolete regulation of G-protein beta subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075162 GO:0051195 biolink:BiologicalProcess obsolete negative regulation of cofactor metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. go-plus.json down-regulation of cofactor metabolic process|downregulation of cofactor metabolic process|negative regulation of cofactor metabolism|down regulation of cofactor metabolic process|inhibition of cofactor metabolic process http://purl.obolibrary.org/obo/GO_0051195 GO:0051196 biolink:BiologicalProcess obsolete regulation of coenzyme metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. go-plus.json regulation of coenzyme and prosthetic group metabolic process|regulation of coenzyme and prosthetic group metabolism|regulation of coenzyme metabolism http://purl.obolibrary.org/obo/GO_0051196 CHEBI:16730 biolink:ChemicalSubstance chloramphenicol 3-acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16730 chebi_ph7_3 GO:0075163 biolink:BiologicalProcess obsolete positive regulation of G-protein beta subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075163 GO:0051193 biolink:BiologicalProcess obsolete regulation of cofactor metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. go-plus.json regulation of cofactor metabolism http://purl.obolibrary.org/obo/GO_0051193 GO:0075164 biolink:BiologicalProcess obsolete negative regulation of G-protein beta subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075164 GO:0075165 biolink:BiologicalProcess obsolete regulation of G-protein gamma subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075165 GO:0051194 biolink:BiologicalProcess obsolete positive regulation of cofactor metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. go-plus.json stimulation of cofactor metabolic process|up-regulation of cofactor metabolic process|activation of cofactor metabolic process|up regulation of cofactor metabolic process|positive regulation of cofactor metabolism|upregulation of cofactor metabolic process http://purl.obolibrary.org/obo/GO_0051194 GO:0051199 biolink:BiologicalProcess regulation of prosthetic group metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. go-plus.json regulation of coenzyme and prosthetic group metabolic process|regulation of prosthetic group metabolism|regulation of coenzyme and prosthetic group metabolism http://purl.obolibrary.org/obo/GO_0051199 GO:0075166 biolink:BiologicalProcess obsolete positive regulation of G-protein gamma subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075166 GO:0075167 biolink:BiologicalProcess obsolete negative regulation of G-protein gamma subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075167 GO:0051197 biolink:BiologicalProcess obsolete positive regulation of coenzyme metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. go-plus.json up regulation of coenzyme metabolic process|positive regulation of coenzyme metabolism|positive regulation of coenzyme and prosthetic group metabolic process|upregulation of coenzyme metabolic process|positive regulation of coenzyme and prosthetic group metabolism|stimulation of coenzyme metabolic process|up-regulation of coenzyme metabolic process|activation of coenzyme metabolic process http://purl.obolibrary.org/obo/GO_0051197 GO:0075168 biolink:BiologicalProcess obsolete regulation of protein kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont protein kinase-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075168 GO:0110018 biolink:BiologicalProcess cap-independent translational initiation of circular RNA The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation. go-plus.json cap-independent translational initiation of circRNA http://purl.obolibrary.org/obo/GO_0110018 GO:0099139 biolink:BiologicalProcess cheating during chimeric sorocarp development Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes. go-plus.json http://purl.obolibrary.org/obo/GO_0099139 GO:0110019 biolink:BiologicalProcess IRES-dependent translational initiation of circular RNA The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation. go-plus.json IRES-dependent translational initiation of circRNA http://purl.obolibrary.org/obo/GO_0110019 GO:0051198 biolink:BiologicalProcess obsolete negative regulation of coenzyme metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. go-plus.json downregulation of coenzyme metabolic process|down regulation of coenzyme metabolic process|negative regulation of coenzyme metabolism|inhibition of coenzyme metabolic process|negative regulation of coenzyme and prosthetic group metabolism|negative regulation of coenzyme and prosthetic group metabolic process|down-regulation of coenzyme metabolic process http://purl.obolibrary.org/obo/GO_0051198 GO:0075169 biolink:BiologicalProcess obsolete positive regulation of symbiont protein kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075169 GO:0099148 biolink:BiologicalProcess regulation of synaptic vesicle docking Any process that modulates the frequency, rate or extent of synaptic vesicle docking. go-plus.json http://purl.obolibrary.org/obo/GO_0099148 goslim_synapse GO:2000915 biolink:BiologicalProcess regulation of glucuronoxylan catabolic process Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process. go-plus.json regulation of glucuronoxylan catabolism http://purl.obolibrary.org/obo/GO_2000915 GO:0110027 biolink:BiologicalProcess negative regulation of DNA strand resection involved in replication fork processing Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing. go-plus.json http://purl.obolibrary.org/obo/GO_0110027 GO:0075159 biolink:BiologicalProcess obsolete regulation of G-protein alpha subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075159 GO:0099149 biolink:BiologicalProcess regulation of postsynaptic neurotransmitter receptor internalization Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse. go-plus.json regulation of postsynaptic neurotransmitter receptor endocytosis http://purl.obolibrary.org/obo/GO_0099149 goslim_synapse GO:2000916 biolink:BiologicalProcess negative regulation of glucuronoxylan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process. go-plus.json negative regulation of glucuronoxylan catabolism http://purl.obolibrary.org/obo/GO_2000916 GO:0110028 biolink:BiologicalProcess positive regulation of mitotic spindle organization Any process that activates or increases the frequency, rate or extent of mitotic spindle organization. go-plus.json http://purl.obolibrary.org/obo/GO_0110028 GO:2000917 biolink:BiologicalProcess positive regulation of glucuronoxylan catabolic process Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process. go-plus.json positive regulation of glucuronoxylan catabolism http://purl.obolibrary.org/obo/GO_2000917 GO:0110025 biolink:BiologicalProcess DNA strand resection involved in replication fork processing The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing. go-plus.json http://purl.obolibrary.org/obo/GO_0110025 GO:0099146 biolink:CellularComponent intrinsic component of postsynaptic density membrane The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic specialization membrane http://purl.obolibrary.org/obo/GO_0099146 goslim_synapse GO:0099147 biolink:CellularComponent extrinsic component of postsynaptic density membrane The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0099147 goslim_synapse GO:2000918 biolink:BiologicalProcess regulation of glucuronoarabinoxylan catabolic process Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process. go-plus.json regulation of glucuronoarabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000918 GO:0110026 biolink:BiologicalProcess regulation of DNA strand resection involved in replication fork processing Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing. go-plus.json http://purl.obolibrary.org/obo/GO_0110026 GO:2000919 biolink:BiologicalProcess negative regulation of glucuronoarabinoxylan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process. go-plus.json negative regulation of glucuronoarabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000919 GO:0110023 biolink:BiologicalProcess negative regulation of cardiac muscle myoblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0110023 GO:0099144 biolink:CellularComponent anchored component of synaptic membrane The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099144 goslim_synapse GO:0099145 biolink:BiologicalProcess regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099145 goslim_synapse GO:0110024 biolink:BiologicalProcess positive regulation of cardiac muscle myoblast proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0110024 GO:0110021 biolink:BiologicalProcess cardiac muscle myoblast proliferation The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. go-plus.json http://purl.obolibrary.org/obo/GO_0110021 GO:0099142 biolink:MolecularActivity intracellularly ATP-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099142 GO:0099143 biolink:CellularComponent presynaptic actin cytoskeleton The actin cytoskeleton that is part of a presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099143 goslim_synapse GO:0110022 biolink:BiologicalProcess regulation of cardiac muscle myoblast proliferation Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0110022 GO:0099140 biolink:BiologicalProcess presynaptic actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0099140 goslim_synapse GO:0110020 biolink:BiologicalProcess regulation of actomyosin structure organization Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. go-plus.json http://purl.obolibrary.org/obo/GO_0110020 GO:0099141 biolink:BiologicalProcess cellular response to protozoan Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan. go-plus.json http://purl.obolibrary.org/obo/GO_0099141 GO:2000910 biolink:BiologicalProcess negative regulation of sterol import Any process that stops, prevents or reduces the frequency, rate or extent of sterol import. go-plus.json negative regulation of sterol uptake|negative regulation of sterol influx http://purl.obolibrary.org/obo/GO_2000910 GO:2000911 biolink:BiologicalProcess positive regulation of sterol import Any process that activates or increases the frequency, rate or extent of sterol import. go-plus.json positive regulation of sterol uptake|positive regulation of sterol influx http://purl.obolibrary.org/obo/GO_2000911 GO:2000912 biolink:BiologicalProcess regulation of galactoglucomannan catabolic process Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process. go-plus.json regulation of galactoglucomannan catabolism http://purl.obolibrary.org/obo/GO_2000912 CHEBI:16728 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16728 GO:2000913 biolink:BiologicalProcess negative regulation of galactoglucomannan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process. go-plus.json negative regulation of galactoglucomannan catabolism http://purl.obolibrary.org/obo/GO_2000913 GO:2000914 biolink:BiologicalProcess positive regulation of galactoglucomannan catabolic process Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process. go-plus.json positive regulation of galactoglucomannan catabolism http://purl.obolibrary.org/obo/GO_2000914 CHEBI:16729 biolink:ChemicalSubstance formyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16729 CHEBI:16727 biolink:ChemicalSubstance 3-maleylpyruvate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16727 chebi_ph7_3 CHEBI:16724 biolink:ChemicalSubstance 4-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16724 chebi_ph7_3 CHEBI:16725 biolink:ChemicalSubstance 2,3-dihydroxy-p-cumic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16725 CHEBI:16723 biolink:ChemicalSubstance 4-methylthio-2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16723 chebi_ph7_3 GO:0075150 biolink:BiologicalProcess obsolete regulation of receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont receptor-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075150 GO:0075151 biolink:BiologicalProcess obsolete positive regulation of receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont receptor-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075151 GO:0075152 biolink:BiologicalProcess obsolete negative regulation of receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont receptor-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075152 GO:0075153 biolink:BiologicalProcess obsolete regulation of transmembrane receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont transmembrane receptor-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075153 GO:0075154 biolink:BiologicalProcess obsolete positive regulation of transmembrane receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075154 GO:0075155 biolink:BiologicalProcess obsolete negative regulation of transmembrane receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont transmembrane receptor-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075155 GO:0075156 biolink:BiologicalProcess obsolete regulation of G protein-coupled receptor signaling pathway in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of G-protein coupled receptor protein signaling pathway in response to host|regulation of G-protein coupled receptor protein signalling pathway in response to host|regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075156 GO:0110029 biolink:BiologicalProcess negative regulation of meiosis I Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0110029 GO:0075157 biolink:BiologicalProcess obsolete positive regulation of G protein-coupled receptor signaling pathway in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of G-protein coupled receptor protein signaling pathway in response to host|positive regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|positive regulation of G-protein coupled receptor protein signalling pathway in response to host http://purl.obolibrary.org/obo/GO_0075157 GO:0075158 biolink:BiologicalProcess obsolete negative regulation of G protein-coupled receptor signaling pathway in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of G-protein coupled receptor protein signaling pathway in response to host|negative regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|negative regulation of G-protein coupled receptor protein signalling pathway in response to host http://purl.obolibrary.org/obo/GO_0075158 GO:0099115 biolink:CellularComponent chromosome, subtelomeric region A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin. SO:0001997 go-plus.json sub-telomeric heterochromatin|subtelomere|nuclear subtelomeric heterochromatin|subtelomeric heterochromatin http://purl.obolibrary.org/obo/GO_0099115 GO:2000926 biolink:BiologicalProcess positive regulation of cellodextrin metabolic process Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process. go-plus.json positive regulation of cellodextrin metabolism http://purl.obolibrary.org/obo/GO_2000926 GO:0110038 biolink:BiologicalProcess negative regulation of nematode male tail tip morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110038 GO:0099116 biolink:BiologicalProcess tRNA 5'-end processing The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA. go-plus.json tRNA 5' processing http://purl.obolibrary.org/obo/GO_0099116 GO:2000927 biolink:BiologicalProcess regulation of cellodextrin catabolic process Any process that modulates the frequency, rate or extent of cellodextrin catabolic process. go-plus.json regulation of cellodextrin catabolism http://purl.obolibrary.org/obo/GO_2000927 GO:0110039 biolink:BiologicalProcess positive regulation of nematode male tail tip morphogenesis Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110039 GO:0099113 biolink:BiologicalProcess negative regulation of presynaptic cytosolic calcium concentration Any process that decreases the concentration of calcium ions in the presynaptic cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0099113 goslim_synapse GO:0110036 biolink:MolecularActivity C2 domain binding Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0110036 GO:2000928 biolink:BiologicalProcess negative regulation of cellodextrin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process. go-plus.json negative regulation of cellodextrin catabolism http://purl.obolibrary.org/obo/GO_2000928 GO:0110037 biolink:BiologicalProcess regulation of nematode male tail tip morphogenesis Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0110037 GO:2000929 biolink:BiologicalProcess positive regulation of cellodextrin catabolic process Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process. go-plus.json positive regulation of cellodextrin catabolism http://purl.obolibrary.org/obo/GO_2000929 GO:0099114 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099114 GO:0110034 biolink:BiologicalProcess negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway. go-plus.json negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0110034 GO:0099111 biolink:BiologicalProcess microtubule-based transport A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0099111 GO:0110035 biolink:MolecularActivity rDNA spacer replication fork barrier binding, bending The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. go-plus.json http://purl.obolibrary.org/obo/GO_0110035 GO:0099112 biolink:BiologicalProcess microtubule polymerization based protein transport The transport of a protein driven by polymerization of a microtubule to which it is attached. go-plus.json http://purl.obolibrary.org/obo/GO_0099112 GO:0110032 biolink:BiologicalProcess positive regulation of G2/MI transition of meiotic cell cycle Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0110032 GO:0110033 biolink:BiologicalProcess regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). go-plus.json regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0110033 GO:0099110 biolink:BiologicalProcess microtubule polymerization based protein transport to cell tip cortex The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached. go-plus.json http://purl.obolibrary.org/obo/GO_0099110 GO:0110030 biolink:BiologicalProcess regulation of G2/MI transition of meiotic cell cycle Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0110030 GO:0110031 biolink:BiologicalProcess negative regulation of G2/MI transition of meiotic cell cycle Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0110031 GO:2000920 biolink:BiologicalProcess positive regulation of glucuronoarabinoxylan catabolic process Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process. go-plus.json positive regulation of glucuronoarabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000920 GO:2000921 biolink:BiologicalProcess regulation of arabinoxylan-containing compound catabolic process Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process. go-plus.json regulation of arabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000921 GO:2000922 biolink:BiologicalProcess negative regulation of arabinoxylan-containing compound catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process. go-plus.json negative regulation of arabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000922 GO:2000923 biolink:BiologicalProcess positive regulation of arabinoxylan-containing compound catabolic process Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process. go-plus.json positive regulation of arabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000923 GO:2000924 biolink:BiologicalProcess regulation of cellodextrin metabolic process Any process that modulates the frequency, rate or extent of cellodextrin metabolic process. go-plus.json regulation of cellodextrin metabolism http://purl.obolibrary.org/obo/GO_2000924 GO:2000925 biolink:BiologicalProcess negative regulation of cellodextrin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process. go-plus.json negative regulation of cellodextrin metabolism http://purl.obolibrary.org/obo/GO_2000925 CHEBI:16758 biolink:ChemicalSubstance 3-dehydrocarnitinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_16758 GO:0075180 biolink:BiologicalProcess obsolete regulation of transcription in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075180 CHEBI:16755 biolink:ChemicalSubstance chenodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16755 GO:0075181 biolink:BiologicalProcess obsolete positive regulation of symbiont transcription in response to host OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075181 CHEBI:16753 biolink:ChemicalSubstance pantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16753 chebi_ph7_3 GO:0075182 biolink:BiologicalProcess obsolete negative regulation of symbiont transcription in response to host OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075182 CHEBI:16754 biolink:ChemicalSubstance 4-carboxymethyl-3-methylbut-2-en-1,4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16754 GO:0075183 biolink:BiologicalProcess infection cushion formation The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass. go-plus.json infection cushion formation on or near host http://purl.obolibrary.org/obo/GO_0075183 CHEBI:16751 biolink:ChemicalSubstance inulobiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16751 chebi_ph7_3 GO:0075184 biolink:BiologicalProcess regulation of infection cushion formation Any process that modulates the frequency, rate or extent of symbiont infection cushion formation. go-plus.json regulation of infection cushion formation on or near host http://purl.obolibrary.org/obo/GO_0075184 GO:0075185 biolink:BiologicalProcess positive regulation of infection cushion formation Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of infection cushion formation on or near host http://purl.obolibrary.org/obo/GO_0075185 CHEBI:16752 biolink:ChemicalSubstance erythro-5-phosphonooxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16752 GO:0075186 biolink:BiologicalProcess negative regulation of infection cushion formation Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of infection cushion formation on or near host http://purl.obolibrary.org/obo/GO_0075186 GO:0075187 biolink:BiologicalProcess hyphopodium formation The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json hyphopodium formation on or near host http://purl.obolibrary.org/obo/GO_0075187 CHEBI:16750 biolink:ChemicalSubstance guanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16750 chebi_ph7_3 GO:0099119 biolink:MolecularActivity 3-demethylubiquinol-8 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-8 = S-adenosyl-L-homocysteine + ubiquinol-8. go-plus.json http://purl.obolibrary.org/obo/GO_0099119 GO:0075188 biolink:BiologicalProcess regulation of hyphopodium formation Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of hyphopodium formation on or near host http://purl.obolibrary.org/obo/GO_0075188 GO:0075189 biolink:BiologicalProcess positive regulation of hyphopodium formation Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of hyphopodium formation on or near host http://purl.obolibrary.org/obo/GO_0075189 GO:0099117 biolink:BiologicalProcess protein transport along microtubule to cell tip The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0099117 GO:0099118 biolink:BiologicalProcess microtubule-based protein transport A microtubule-based process that results in the transport of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0099118 GO:2000937 biolink:BiologicalProcess negative regulation of cellotriose catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process. go-plus.json negative regulation of cellotriose catabolism http://purl.obolibrary.org/obo/GO_2000937 GO:0099126 biolink:CellularComponent transforming growth factor beta complex A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP. go-plus.json TGF-beta complex|TGFbeta dimer|TGFbeta complex|TGFB dimer|TGFB complex|TGF-beta dimer http://purl.obolibrary.org/obo/GO_0099126 GO:0099127 biolink:BiologicalProcess envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0099127 GO:2000938 biolink:BiologicalProcess positive regulation of cellotriose catabolic process Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process. go-plus.json positive regulation of cellotriose catabolism http://purl.obolibrary.org/obo/GO_2000938 GO:2000939 biolink:BiologicalProcess regulation of plant-type cell wall cellulose catabolic process Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process. go-plus.json regulation of plant-type cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_2000939 GO:0099124 biolink:BiologicalProcess axonal dopamine secretion The regulated release of dopamine from an axon. go-plus.json axonal DA release|axonal dopamine release http://purl.obolibrary.org/obo/GO_0099124 GO:0099125 biolink:CellularComponent PAK family kinase-Sog2 complex A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network. go-plus.json http://purl.obolibrary.org/obo/GO_0099125 GO:0110045 biolink:BiologicalProcess negative regulation of cell cycle switching, mitotic to meiotic cell cycle Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division. go-plus.json http://purl.obolibrary.org/obo/GO_0110045 GO:0099122 biolink:MolecularActivity RNA polymerase II C-terminal domain binding Binding to the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function. go-plus.json RNAP II C-terminal binding http://purl.obolibrary.org/obo/GO_0099122 GO:0110046 biolink:BiologicalProcess signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0110046 GO:0099123 biolink:BiologicalProcess somato-dendritic dopamine secretion The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. go-plus.json somatodendritic dopamine release|STD DA release|STD dopamine release http://purl.obolibrary.org/obo/GO_0099123 GO:0110043 biolink:BiologicalProcess positive regulation of pharynx morphogenesis Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110043 GO:0099120 biolink:BiologicalProcess socially cooperative development The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies. go-plus.json socially co-operative development|colonial development|non-reproductive fruiting body development http://purl.obolibrary.org/obo/GO_0099120 GO:0110044 biolink:BiologicalProcess regulation of cell cycle switching, mitotic to meiotic cell cycle Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division. go-plus.json sexual differentiation http://purl.obolibrary.org/obo/GO_0110044 GO:0099121 biolink:BiologicalProcess fungal sorus development The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure. go-plus.json http://purl.obolibrary.org/obo/GO_0099121 GO:0110041 biolink:BiologicalProcess regulation of pharynx morphogenesis Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0110041 GO:0110042 biolink:BiologicalProcess negative regulation of pharynx morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110042 GO:2000930 biolink:BiologicalProcess regulation of cellobiose metabolic process Any process that modulates the frequency, rate or extent of cellobiose metabolic process. go-plus.json regulation of cellobiose metabolism http://purl.obolibrary.org/obo/GO_2000930 GO:2000931 biolink:BiologicalProcess negative regulation of cellobiose metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process. go-plus.json negative regulation of cellobiose metabolism http://purl.obolibrary.org/obo/GO_2000931 GO:2000932 biolink:BiologicalProcess positive regulation of cellobiose metabolic process Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process. go-plus.json positive regulation of cellobiose metabolism http://purl.obolibrary.org/obo/GO_2000932 GO:0110040 biolink:BiologicalProcess pharynx morphogenesis The process in which the anatomical structures of the pharynx are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0110040 GO:2000933 biolink:BiologicalProcess regulation of cellotriose metabolic process Any process that modulates the frequency, rate or extent of cellotriose metabolic process. go-plus.json regulation of cellotriose metabolism http://purl.obolibrary.org/obo/GO_2000933 GO:2000934 biolink:BiologicalProcess negative regulation of cellotriose metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process. go-plus.json negative regulation of cellotriose metabolism http://purl.obolibrary.org/obo/GO_2000934 GO:2000935 biolink:BiologicalProcess positive regulation of cellotriose metabolic process Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process. go-plus.json positive regulation of cellotriose metabolism http://purl.obolibrary.org/obo/GO_2000935 GO:2000936 biolink:BiologicalProcess regulation of cellotriose catabolic process Any process that modulates the frequency, rate or extent of cellotriose catabolic process. go-plus.json regulation of cellotriose catabolism http://purl.obolibrary.org/obo/GO_2000936 CHEBI:16749 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16749 CHEBI:16746 biolink:ChemicalSubstance 1,2,3,5-tetrahydroxybenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16746 chebi_ph7_3 CHEBI:16747 biolink:ChemicalSubstance 4-methylene-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16747 CHEBI:16744 biolink:ChemicalSubstance pregna-4,9(11)-diene-3,20-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16744 chebi_ph7_3 GO:0075170 biolink:BiologicalProcess obsolete negative regulation of protein kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont protein kinase-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075170 GO:0075171 biolink:BiologicalProcess obsolete regulation of MAP kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont MAP kinase-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075171 CHEBI:16742 biolink:ChemicalSubstance orotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16742 GO:0075172 biolink:BiologicalProcess obsolete positive regulation of MAP kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont MAP kinase-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075172 CHEBI:16743 biolink:ChemicalSubstance D-tagatose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16743 GO:0075173 biolink:BiologicalProcess obsolete negative regulation of MAP kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont MAP kinase-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075173 CHEBI:16740 biolink:ChemicalSubstance trans-cyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16740 chebi_ph7_3 GO:0075174 biolink:BiologicalProcess obsolete regulation of cAMP-mediated signaling in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of cAMP-mediated signalling in response to host|regulation of symbiont cAMP-mediated signal transduction in response to host|regulation of cAMP-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075174 CHEBI:16741 biolink:ChemicalSubstance 4-(beta-D-glucosyloxy)benzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16741 GO:0075175 biolink:BiologicalProcess obsolete positive regulation of cAMP-mediated signaling in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of cAMP-mediated signalling in response to host|positive regulation of cAMP-mediated signal transduction in response to host|positive regulation of symbiont cAMP-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075175 GO:0075176 biolink:BiologicalProcess obsolete negative regulation of cAMP-mediated signaling in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signalling in response to host http://purl.obolibrary.org/obo/GO_0075176 UBERON:0008397 biolink:AnatomicalEntity tracheobronchial epithelium Epithelium pertaining to the trachea and bronchi. go-plus.json bronchotracheal epithelium http://purl.obolibrary.org/obo/UBERON_0008397 GO:0075177 biolink:BiologicalProcess obsolete regulation of calcium or calmodulin-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host|modulation of symbiont calcium or calmodulin-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075177 GO:0075178 biolink:BiologicalProcess obsolete positive regulation of calcium or calmodulin-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|positive regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075178 GO:0099128 biolink:CellularComponent mitochondrial iron-sulfur cluster assembly complex A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0099128 GO:0075179 biolink:BiologicalProcess obsolete negative regulation of calcium or calmodulin-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|negative regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075179 GO:0099129 biolink:BiologicalProcess cochlear outer hair cell electromotile response A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification. go-plus.json http://purl.obolibrary.org/obo/GO_0099129 GO:0099179 biolink:BiologicalProcess regulation of synaptic membrane adhesion Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes. go-plus.json regulation of synapse adhesion between pre- and post-synapse http://purl.obolibrary.org/obo/GO_0099179 goslim_synapse GO:0099177 biolink:BiologicalProcess regulation of trans-synaptic signaling Any process that modulates the frequency, rate or extent of trans-synaptic signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0099177 GO:0099178 biolink:BiologicalProcess regulation of retrograde trans-synaptic signaling by endocanabinoid Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid. go-plus.json regulation of endocannabinoid-mediated retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099178 GO:0099175 biolink:BiologicalProcess regulation of postsynapse organization Any process that modulates the physical form of a postsynapse. go-plus.json regulation of postsynapse organisation|regulation of postsynapse structure|regulation of postsynapse organization and biogenesis http://purl.obolibrary.org/obo/GO_0099175 goslim_synapse GO:0099176 biolink:BiologicalProcess regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex. go-plus.json regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099176 goslim_synapse GO:0099173 biolink:BiologicalProcess postsynapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. go-plus.json postsynapse organization and biogenesis|postsynapse morphogenesis|postsynapse organisation|postsynapse development http://purl.obolibrary.org/obo/GO_0099173 goslim_synapse GO:0099174 biolink:BiologicalProcess regulation of presynapse organization Any process that modulates the physical form of a presynapse. go-plus.json regulation of presynapse organisation|regulation of presynapse structure|regulation of presynapse organization and biogenesis http://purl.obolibrary.org/obo/GO_0099174 goslim_synapse GO:0099171 biolink:BiologicalProcess presynaptic modulation of chemical synaptic transmission Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0099171 goslim_synapse GO:0099172 biolink:BiologicalProcess presynapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. go-plus.json presynapse development|presynapse organisation|presynapse organization and biogenesis|presynapse morphogenesis http://purl.obolibrary.org/obo/GO_0099172 goslim_synapse GO:0099170 biolink:BiologicalProcess postsynaptic modulation of chemical synaptic transmission Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0099170 goslim_synapse GO:0099188 biolink:BiologicalProcess postsynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0099188 goslim_synapse GO:0099189 biolink:CellularComponent postsynaptic spectrin-associated cytoskeleton The portion of the spectrin-associated cytoskeleton contained within the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099189 goslim_synapse GO:0099186 biolink:MolecularActivity structural constituent of postsynapse The action of a molecule that contributes to the structural integrity of a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099186 goslim_synapse GO:0099187 biolink:BiologicalProcess presynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0099187 GO:0099184 biolink:MolecularActivity structural constituent of postsynaptic intermediate filament cytoskeleton The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0099184 goslim_synapse GO:0099185 biolink:BiologicalProcess postsynaptic intermediate filament cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0099185 goslim_synapse GO:0099182 biolink:CellularComponent presynaptic intermediate filament cytoskeleton The intermediate filament cytoskeleton that is part of a presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099182 goslim_synapse GO:0099183 biolink:BiologicalProcess trans-synaptic signaling by BDNF, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099183 goslim_synapse GO:0099180 biolink:BiologicalProcess zinc ion import into synaptic vesicle The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle. go-plus.json Zn2+ import into synaptic vesicle|zinc import into synaptic vesicle http://purl.obolibrary.org/obo/GO_0099180 goslim_synapse GO:0099181 biolink:MolecularActivity structural constituent of presynapse The action of a molecule that contributes to the structural integrity of a presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099181 goslim_synapse GO:0075190 biolink:BiologicalProcess negative regulation of hyphopodium formation Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of hyphopodium formation on or near host http://purl.obolibrary.org/obo/GO_0075190 GO:0075191 biolink:BiologicalProcess obsolete autophagy of host cells on or near symbiont surface OBSOLETE. The process in which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075191 GO:0075192 biolink:BiologicalProcess haustorium mother cell formation The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json haustorium mother cell formation on or near host http://purl.obolibrary.org/obo/GO_0075192 GO:0075193 biolink:BiologicalProcess regulation of haustorium mother cell formation Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of haustorium mother cell formation on or near host http://purl.obolibrary.org/obo/GO_0075193 GO:0075194 biolink:BiologicalProcess positive regulation of haustorium mother cell formation Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of haustorium mother cell formation on or near host http://purl.obolibrary.org/obo/GO_0075194 GO:0075195 biolink:BiologicalProcess negative regulation of haustorium mother cell formation Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of haustorium mother cell formation on or near host http://purl.obolibrary.org/obo/GO_0075195 GO:0075196 biolink:BiologicalProcess adhesion of symbiont haustorium mother cell to host The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion of symbiont haustorium mother cell to host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075196 GO:0075197 biolink:BiologicalProcess haustorium neck formation The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation of symbiont haustorium neck for entry into host|symbiont haustorium neck formation for entry into host http://purl.obolibrary.org/obo/GO_0075197 GO:0075198 biolink:BiologicalProcess modulation of symbiont haustorium neck formation for entry into host Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075198 GO:0075199 biolink:BiologicalProcess positive regulation of symbiont haustorium neck formation for entry into host Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075199 GO:0099159 biolink:BiologicalProcess regulation of modification of postsynaptic structure Any process that modulates the frequency, rate or extent of modification of postsynaptic structure. go-plus.json regulation of postsynapse remodelling http://purl.obolibrary.org/obo/GO_0099159 goslim_synapse GO:0099157 biolink:BiologicalProcess trans-synaptic signalling via exosome Transynaptic signaling in which the ligand is carried across the synapse by an exosome. go-plus.json exosome mediated transynaptic signalling http://purl.obolibrary.org/obo/GO_0099157 goslim_synapse GO:0099158 biolink:BiologicalProcess regulation of recycling endosome localization within postsynapse Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099158 goslim_synapse GO:0099155 biolink:BiologicalProcess synaptic transmission, noradrenergic The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json noradrenergic synaptic transmission http://purl.obolibrary.org/obo/GO_0099155 GO:0099156 biolink:BiologicalProcess cell-cell signaling via exosome Cell-cell signaling in which the ligand is carried between cells by an exosome. go-plus.json exosome mediated http://purl.obolibrary.org/obo/GO_0099156 GO:0099153 biolink:BiologicalProcess synaptic transmission, serotonergic The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json serotonergic synaptic transmission http://purl.obolibrary.org/obo/GO_0099153 GO:0099154 biolink:CellularComponent serotonergic synapse A synapse that uses serotonin as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0099154 goslim_synapse GO:0099151 biolink:BiologicalProcess regulation of postsynaptic density assembly Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density. go-plus.json http://purl.obolibrary.org/obo/GO_0099151 goslim_synapse GO:0099152 biolink:BiologicalProcess regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0099152 goslim_synapse CHEBI:145182 biolink:ChemicalSubstance 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_145182 chebi_ph7_3 GO:0099150 biolink:BiologicalProcess regulation of postsynaptic specialization assembly Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization. go-plus.json http://purl.obolibrary.org/obo/GO_0099150 goslim_synapse CHEBI:16719 biolink:ChemicalSubstance (R)-pantolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16719 chebi_ph7_3 CHEBI:145187 biolink:ChemicalSubstance 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_145187 chebi_ph7_3 CHEBI:16717 biolink:ChemicalSubstance (Z)-but-2-ene-1,2,3-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16717 CHEBI:16718 biolink:ChemicalSubstance (S)-reticuline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16718 CHEBI:65737 biolink:ChemicalSubstance demethoxycurcumin go-plus.json http://purl.obolibrary.org/obo/CHEBI_65737 chebi_ph7_3 CHEBI:16715 biolink:ChemicalSubstance 1,5-anhydro-D-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16715 chebi_ph7_3 CHEBI:16716 biolink:ChemicalSubstance benzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16716 chebi_ph7_3 CHEBI:16713 biolink:ChemicalSubstance 2-aminopteridine-4,7-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16713 chebi_ph7_3 CHEBI:16714 biolink:ChemicalSubstance codeine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16714 CHEBI:16711 biolink:ChemicalSubstance 4-hydroxybut-2-ynal go-plus.json http://purl.obolibrary.org/obo/CHEBI_16711 chebi_ph7_3 CHEBI:16712 biolink:ChemicalSubstance (S)-3-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16712 CHEBI:16710 biolink:ChemicalSubstance D-ribulose 1,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16710 CHEBI:145178 biolink:ChemicalSubstance 1-O-octadecyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_145178 chebi_ph7_3 GO:0110005 biolink:BiologicalProcess positive regulation of tRNA C5-cytosine methylation Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0110005 GO:0099168 biolink:CellularComponent extrinsic component of postsynaptic specialization membrane of symmetric synapse The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0099168 goslim_synapse GO:0110003 biolink:BiologicalProcess regulation of tRNA C5-cytosine methylation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0110003 GO:0110004 biolink:BiologicalProcess positive regulation of tRNA methylation Any process that activates or increases the frequency, rate or extent of tRNA methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0110004 GO:0099169 biolink:CellularComponent anchored component of postsynaptic specialization membrane of symmetric synapse The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0099169 goslim_synapse GO:0099166 biolink:CellularComponent intrinsic component of postsynaptic specialization membrane of symmetric synapse The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic specialization membrane of symmetric synapse http://purl.obolibrary.org/obo/GO_0099166 goslim_synapse GO:0110001 biolink:CellularComponent toxin-antitoxin complex A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon. go-plus.json http://purl.obolibrary.org/obo/GO_0110001 GO:0099167 biolink:CellularComponent integral component of postsynaptic specialization membrane of symmetric synapse The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099167 goslim_synapse GO:0110002 biolink:BiologicalProcess regulation of tRNA methylation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0110002 GO:0099164 biolink:CellularComponent postsynaptic specialization membrane of symmetric synapse The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. go-plus.json http://purl.obolibrary.org/obo/GO_0099164 goslim_synapse GO:0099165 biolink:CellularComponent postsynaptic specialization of symmetric synapse, intracellular component A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses. go-plus.json http://purl.obolibrary.org/obo/GO_0099165 goslim_synapse GO:0099162 biolink:BiologicalProcess regulation of neurotransmitter loading into synaptic vesicle Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles. go-plus.json regulation of synaptic vesicle neurotransmitter loading|regulation of neurotransmitter uptake into synaptic vesicle http://purl.obolibrary.org/obo/GO_0099162 goslim_synapse GO:0099163 biolink:BiologicalProcess synaptic signaling by nitric oxide Cell-cell signaling to or from a synapse, mediated by nitric oxide. go-plus.json http://purl.obolibrary.org/obo/GO_0099163 goslim_synapse GO:0099160 biolink:CellularComponent postsynaptic intermediate filament cytoskeleton The intermediate filament cytoskeleton that is part of a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099160 goslim_synapse GO:0099161 biolink:BiologicalProcess regulation of presynaptic dense core granule exocytosis Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis. go-plus.json regulation of presynaptic dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_0099161 goslim_synapse CHEBI:16708 biolink:ChemicalSubstance adenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16708 chebi_ph7_3 CHEBI:16709 biolink:ChemicalSubstance pyridoxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16709 chebi_ph7_3 CHEBI:16706 biolink:ChemicalSubstance 2-iodophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16706 chebi_ph7_3 CHEBI:16704 biolink:ChemicalSubstance uridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16704 chebi_ph7_3 CHEBI:16705 biolink:ChemicalSubstance 6-aminopenicillanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16705 CHEBI:16702 biolink:ChemicalSubstance N-sulfo-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16702 CHEBI:16700 biolink:ChemicalSubstance indican go-plus.json http://purl.obolibrary.org/obo/CHEBI_16700 chebi_ph7_3 CHEBI:16701 biolink:ChemicalSubstance nucleoside 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16701 GO:0110009 biolink:BiologicalProcess formin-nucleated actin cable organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable. go-plus.json http://purl.obolibrary.org/obo/GO_0110009 GO:0110008 biolink:BiologicalProcess ncRNA deadenylation Shortening of the poly(A) tail of a nuclear-transcribed ncRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0110008 GO:0051115 biolink:BiologicalProcess obsolete enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine OBSOLETE. The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine). RESID:AA0372 go-plus.json http://purl.obolibrary.org/obo/GO_0051115 GO:0051116 biolink:MolecularActivity cobaltochelatase activity Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate. KEGG_REACTION:R05227|MetaCyc:R342-RXN|EC:6.6.1.2|RHEA:15341 go-plus.json hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)|hydrogenobyrinic acid a,c-diamide cobaltochelatase activity|CobN-CobST|CobNST http://purl.obolibrary.org/obo/GO_0051116 GO:0051113 biolink:BiologicalProcess obsolete enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine OBSOLETE. The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine). RESID:AA0371 go-plus.json http://purl.obolibrary.org/obo/GO_0051113 GO:0051114 biolink:BiologicalProcess peptidyl-histidine uridylylation The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine). RESID:AA0372 go-plus.json http://purl.obolibrary.org/obo/GO_0051114 GO:0051119 biolink:MolecularActivity sugar transmembrane transporter activity Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides. Reactome:R-HSA-428779|Reactome:R-HSA-8876319|Reactome:R-HSA-8875902 go-plus.json sugar/polyol channel activity http://purl.obolibrary.org/obo/GO_0051119 CHEBI:26147 biolink:ChemicalSubstance piperidine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26147 CHEBI:26148 biolink:ChemicalSubstance piperidinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26148 GO:0110098 biolink:BiologicalProcess positive regulation of calcium import into the mitochondrion Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0110098 GO:0051117 biolink:MolecularActivity ATPase binding Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0051117 GO:0051118 biolink:MolecularActivity glucan endo-1,3-alpha-glucosidase activity Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran. EC:3.2.1.59|MetaCyc:3.2.1.59-RXN go-plus.json cariogenanase activity|endo-1,3-alpha-glucanase activity|mutanase activity|cariogenase activity|endo-(1->3)-alpha-glucanase activity|1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity|endo-1,3-alpha-D-glucanase activity http://purl.obolibrary.org/obo/GO_0051118 GO:0110099 biolink:BiologicalProcess negative regulation of calcium import into the mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0110099 GO:2000984 biolink:BiologicalProcess negative regulation of ATP citrate synthase activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity. go-plus.json negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|negative regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|negative regulation of ATP-citric lyase activity|negative regulation of citric cleavage enzyme activity|negative regulation of adenosine triphosphate citrate lyase activity|negative regulation of ATP-citrate (pro-S)-lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|negative regulation of ATP-citrate (pro-S-)-lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|negative regulation of ATP citrate (pro-S)-lyase activity|negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|negative regulation of citrate-ATP lyase activity|negative regulation of citrate cleavage enzyme activity http://purl.obolibrary.org/obo/GO_2000984 GO:0110096 biolink:BiologicalProcess cellular response to aldehyde Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0110096 GO:2000985 biolink:BiologicalProcess positive regulation of ATP citrate synthase activity Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity. go-plus.json positive regulation of citrate cleavage enzyme activity|positive regulation of ATP-citric lyase activity|positive regulation of citric cleavage enzyme activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|positive regulation of adenosine triphosphate citrate lyase activity|positive regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|positive regulation of ATP-citrate (pro-S)-lyase activity|positive regulation of ATP-citrate (pro-S-)-lyase activity|positive regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|positive regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|positive regulation of ATP citrate (pro-S)-lyase activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|positive regulation of citrate-ATP lyase activity http://purl.obolibrary.org/obo/GO_2000985 CHEBI:26144 biolink:ChemicalSubstance piperazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26144 GO:0110097 biolink:BiologicalProcess regulation of calcium import into the mitochondrion Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0110097 GO:0110094 biolink:BiologicalProcess polyphosphate-mediated signaling Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal. go-plus.json polyphosphate signaling http://purl.obolibrary.org/obo/GO_0110094 GO:0090718 biolink:BiologicalProcess adaptive immune effector response An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0090718 GO:2000986 biolink:BiologicalProcess negative regulation of behavioral fear response Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response. go-plus.json negative regulation of behavioural fear response http://purl.obolibrary.org/obo/GO_2000986 CHEBI:26145 biolink:ChemicalSubstance piperideine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26145 GO:2000987 biolink:BiologicalProcess positive regulation of behavioral fear response Any process that activates or increases the frequency, rate or extent of behavioral fear response. go-plus.json positive regulation of behavioural fear response http://purl.obolibrary.org/obo/GO_2000987 GO:0090719 biolink:BiologicalProcess adaptive immune effector response involving T cells and B lineage cells An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090719 GO:0110095 biolink:BiologicalProcess cellular detoxification of aldehyde Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. go-plus.json http://purl.obolibrary.org/obo/GO_0110095 GO:0110092 biolink:CellularComponent nucleus leading edge The area of a motile nucleus closest to the direction of movement. go-plus.json horsetail nucleus leading edge http://purl.obolibrary.org/obo/GO_0110092 GO:2000988 biolink:BiologicalProcess regulation of hemicellulose catabolic process Any process that modulates the frequency, rate or extent of hemicellulose catabolic process. go-plus.json regulation of hemicellulose catabolism http://purl.obolibrary.org/obo/GO_2000988 GO:0110093 biolink:CellularComponent nucleus lagging edge The area of a motile nucleus furthest from the direction of movement. go-plus.json http://purl.obolibrary.org/obo/GO_0110093 GO:2000989 biolink:BiologicalProcess negative regulation of hemicellulose catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process. go-plus.json negative regulation of hemicellulose catabolism http://purl.obolibrary.org/obo/GO_2000989 GO:1905530 biolink:BiologicalProcess negative regulation of uracil import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905530 GO:0110090 biolink:BiologicalProcess positive regulation of hippocampal neuron apoptotic process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0110090 GO:0110091 biolink:BiologicalProcess negative regulation of hippocampal neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0110091 GO:1905531 biolink:BiologicalProcess positive regulation of uracil import across plasma membrane Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905531 GO:1905521 biolink:BiologicalProcess regulation of macrophage migration Any process that modulates the frequency, rate or extent of macrophage migration. go-plus.json http://purl.obolibrary.org/obo/GO_1905521 GO:0090723 biolink:CellularComponent obsolete growth cone part OBSOLETE. Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0090723 GO:0090724 biolink:CellularComponent central region of growth cone The center of the migrating motile tip of a growing nerve cell axon or dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0090724 GO:1905522 biolink:BiologicalProcess negative regulation of macrophage migration Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. go-plus.json down-regulation of macrophage migration|downregulation of macrophage migration|down regulation of macrophage migration|inhibition of macrophage migration http://purl.obolibrary.org/obo/GO_1905522 GO:0090721 biolink:BiologicalProcess primary adaptive immune response involving T cells and B cells An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system. go-plus.json http://purl.obolibrary.org/obo/GO_0090721 GO:1905523 biolink:BiologicalProcess positive regulation of macrophage migration Any process that activates or increases the frequency, rate or extent of macrophage migration. go-plus.json up regulation of macrophage migration|upregulation of macrophage migration|up-regulation of macrophage migration|activation of macrophage migration http://purl.obolibrary.org/obo/GO_1905523 GO:0090722 biolink:MolecularActivity receptor-receptor interaction The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function. go-plus.json hetero-receptor complex formation http://purl.obolibrary.org/obo/GO_0090722 GO:1905524 biolink:BiologicalProcess negative regulation of protein autoubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination. go-plus.json negative regulation of protein self-ubiquitination|down-regulation of protein self-ubiquitination|negative regulation of protein auto-ubiquitination|down-regulation of protein auto-ubiquitination|downregulation of protein autoubiquitination|inhibition of protein self-ubiquitination|down regulation of protein self-ubiquitinylation|inhibition of protein auto-ubiquitination|down regulation of protein autoubiquitination|down regulation of protein auto-ubiquitinylation|downregulation of protein self-ubiquitinylation|inhibition of protein autoubiquitination|downregulation of protein auto-ubiquitinylation|down-regulation of protein autoubiquitinylation|negative regulation of protein autoubiquitinylation|down regulation of protein self-ubiquitination|down-regulation of protein self-ubiquitinylation|negative regulation of protein self-ubiquitinylation|negative regulation of protein auto-ubiquitinylation|down-regulation of protein auto-ubiquitinylation|down regulation of protein auto-ubiquitination|downregulation of protein self-ubiquitination|downregulation of protein autoubiquitinylation|inhibition of protein self-ubiquitinylation|downregulation of protein auto-ubiquitination|down-regulation of protein autoubiquitination|inhibition of protein auto-ubiquitinylation|down regulation of protein autoubiquitinylation|inhibition of protein autoubiquitinylation http://purl.obolibrary.org/obo/GO_1905524 GO:1905525 biolink:BiologicalProcess obsolete regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter in response to iron that results in regulation of ferrichrome biosynthetic process. go-plus.json regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron http://purl.obolibrary.org/obo/GO_1905525 GO:0090727 biolink:BiologicalProcess positive regulation of brood size Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time. go-plus.json http://purl.obolibrary.org/obo/GO_0090727 GO:2000980 biolink:BiologicalProcess regulation of inner ear receptor cell differentiation Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. go-plus.json regulation of inner ear hair cell differentiation http://purl.obolibrary.org/obo/GO_2000980 GO:0090728 biolink:BiologicalProcess negative regulation of brood size Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time. go-plus.json http://purl.obolibrary.org/obo/GO_0090728 GO:2000981 biolink:BiologicalProcess negative regulation of inner ear receptor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation. go-plus.json negative regulation of inner ear hair cell differentiation http://purl.obolibrary.org/obo/GO_2000981 GO:1905526 biolink:BiologicalProcess regulation of Golgi lumen acidification Any process that modulates the frequency, rate or extent of Golgi lumen acidification. go-plus.json http://purl.obolibrary.org/obo/GO_1905526 GO:2000982 biolink:BiologicalProcess positive regulation of inner ear receptor cell differentiation Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation. go-plus.json positive regulation of inner ear hair cell differentiation http://purl.obolibrary.org/obo/GO_2000982 GO:0090725 biolink:CellularComponent peripheral region of growth cone The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0090725 GO:1905527 biolink:BiologicalProcess negative regulation of Golgi lumen acidification Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification. go-plus.json down regulation of Golgi lumen acidification|downregulation of Golgi lumen acidification|down-regulation of Golgi lumen acidification|inhibition of Golgi lumen acidification http://purl.obolibrary.org/obo/GO_1905527 GO:2000983 biolink:BiologicalProcess regulation of ATP citrate synthase activity Any process that modulates the frequency, rate or extent of ATP citrate synthase activity. go-plus.json regulation of ATP citrate (pro-S)-lyase activity|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|regulation of citrate-ATP lyase activity|regulation of citrate cleavage enzyme activity|regulation of ATP-citrate (pro-S-)-lyase activity|regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|regulation of ATP-citrate (pro-S)-lyase activity|regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|regulation of ATP-citric lyase activity|regulation of citric cleavage enzyme activity|regulation of adenosine triphosphate citrate lyase activity http://purl.obolibrary.org/obo/GO_2000983 GO:0090726 biolink:CellularComponent cortical dynamic polarity patch A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation. go-plus.json dynamic polarity patch at the cell cortex http://purl.obolibrary.org/obo/GO_0090726 GO:1905528 biolink:BiologicalProcess positive regulation of Golgi lumen acidification Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification. go-plus.json upregulation of Golgi lumen acidification|up regulation of Golgi lumen acidification|activation of Golgi lumen acidification|up-regulation of Golgi lumen acidification http://purl.obolibrary.org/obo/GO_1905528 GO:1905529 biolink:BiologicalProcess regulation of uracil import across plasma membrane Any process that modulates the frequency, rate or extent of uracil import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905529 UBERON:0008342 biolink:AnatomicalEntity intestinal villus of duodenum An intestinal villus in the duodenum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008342 GO:0051111 biolink:BiologicalProcess peptidyl-histidine adenylylation The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine). RESID:AA0371 go-plus.json http://purl.obolibrary.org/obo/GO_0051111 GO:0051112 biolink:BiologicalProcess peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine). RESID:AA0371 go-plus.json http://purl.obolibrary.org/obo/GO_0051112 GO:0090720 biolink:BiologicalProcess primary adaptive immune response An adaptive immune response against an antigen not previously encountered by immune system. go-plus.json http://purl.obolibrary.org/obo/GO_0090720 GO:0051110 biolink:BiologicalProcess peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine). RESID:AA0372 go-plus.json http://purl.obolibrary.org/obo/GO_0051110 UBERON:0008346 biolink:AnatomicalEntity duodenal epithelium An epithelium that is part of a duodenum. go-plus.json epithelium of duodenum http://purl.obolibrary.org/obo/UBERON_0008346 GO:0051126 biolink:BiologicalProcess negative regulation of actin nucleation Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. go-plus.json downregulation of actin nucleation|down regulation of actin nucleation|inhibition of actin nucleation|down-regulation of actin nucleation http://purl.obolibrary.org/obo/GO_0051126 GO:0051127 biolink:BiologicalProcess positive regulation of actin nucleation Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. go-plus.json up regulation of actin nucleation|upregulation of actin nucleation|stimulation of actin nucleation|up-regulation of actin nucleation|activation of actin nucleation http://purl.obolibrary.org/obo/GO_0051127 GO:0051124 biolink:BiologicalProcess synaptic assembly at neuromuscular junction The assembly of a synapse at a neuromuscular junction. go-plus.json cholinergic synaptogenesis|synaptic growth at neuromuscular junction http://purl.obolibrary.org/obo/GO_0051124 GO:0051125 biolink:BiologicalProcess regulation of actin nucleation Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. go-plus.json http://purl.obolibrary.org/obo/GO_0051125 GO:0051128 biolink:BiologicalProcess regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. go-plus.json regulation of cellular component organisation|regulation of cell organisation|regulation of cell organization|regulation of cellular component organization and biogenesis http://purl.obolibrary.org/obo/GO_0051128 GO:0051129 biolink:BiologicalProcess negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. go-plus.json down regulation of cell organization|downregulation of cell organization|down-regulation of cell organization|negative regulation of cellular component organization and biogenesis|negative regulation of cell organisation|inhibition of cell organization http://purl.obolibrary.org/obo/GO_0051129 GO:2000995 biolink:BiologicalProcess negative regulation of mannan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process. go-plus.json negative regulation of mannan catabolism|negative regulation of mannan degradation|negative regulation of mannan breakdown http://purl.obolibrary.org/obo/GO_2000995 GO:2000996 biolink:BiologicalProcess positive regulation of mannan catabolic process Any process that activates or increases the frequency, rate or extent of mannan catabolic process. go-plus.json positive regulation of mannan degradation|positive regulation of mannan breakdown|positive regulation of mannan catabolism http://purl.obolibrary.org/obo/GO_2000996 CHEBI:26155 biolink:ChemicalSubstance plant growth regulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_26155 GO:0090729 biolink:MolecularActivity toxin activity Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom. Wikipedia:Toxin go-plus.json toxin receptor binding http://purl.obolibrary.org/obo/GO_0090729 GO:2000997 biolink:BiologicalProcess regulation of cellulose catabolic process Any process that modulates the frequency, rate or extent of cellulose catabolic process. go-plus.json regulation of cellulose degradation|regulation of cellulose catabolism|regulation of cellulose breakdown http://purl.obolibrary.org/obo/GO_2000997 GO:2000998 biolink:BiologicalProcess negative regulation of cellulose catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process. go-plus.json negative regulation of cellulose degradation|negative regulation of cellulose breakdown|negative regulation of cellulose catabolism http://purl.obolibrary.org/obo/GO_2000998 GO:2000999 biolink:BiologicalProcess positive regulation of cellulose catabolic process Any process that activates or increases the frequency, rate or extent of cellulose catabolic process. go-plus.json positive regulation of cellulose degradation|positive regulation of cellulose breakdown|positive regulation of cellulose catabolism http://purl.obolibrary.org/obo/GO_2000999 GO:1905540 biolink:CellularComponent interleukin-7 receptor complex A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors. go-plus.json IL-7-receptor complex|IL7-receptor complex|IL-7 receptor complex|IL7 receptor complex http://purl.obolibrary.org/obo/GO_1905540 CHEBI:26151 biolink:ChemicalSubstance piperidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_26151 GO:1905541 biolink:BiologicalProcess regulation of L-arginine import across plasma membrane Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane. go-plus.json regulation of L-arginine import into cell http://purl.obolibrary.org/obo/GO_1905541 NCBITaxon:4429 biolink:OrganismalEntity Nelumbonaceae go-plus.json lotus family http://purl.obolibrary.org/obo/NCBITaxon_4429 GO:1905542 biolink:BiologicalProcess negative regulation of L-arginine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane. go-plus.json inhibition of L-arginine import into cell|negative regulation of L-arginine import into cell|down regulation of L-arginine import into cell|downregulation of L-arginine import into cell http://purl.obolibrary.org/obo/GO_1905542 CHEBI:26153 biolink:ChemicalSubstance p-menthadien-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_26153 GO:0090734 biolink:CellularComponent site of DNA damage A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. Wikipedia:DNA_repair go-plus.json http://purl.obolibrary.org/obo/GO_0090734 GO:1905532 biolink:BiologicalProcess regulation of leucine import across plasma membrane Any process that modulates the frequency, rate or extent of leucine import across plasma membrane. go-plus.json regulation of leucine import into cell|regulation of L-leucine import into cell http://purl.obolibrary.org/obo/GO_1905532 GO:1905533 biolink:BiologicalProcess negative regulation of leucine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane. go-plus.json negative regulation of L-leucine import into cell|down-regulation of L-leucine import into cell|down-regulation of leucine import into cell|downregulation of L-leucine import into cell|down regulation of L-leucine import into cell|downregulation of leucine import into cell|down regulation of leucine import into cell|inhibition of L-leucine import into cell|inhibition of leucine import into cell|negative regulation of leucine import into cell http://purl.obolibrary.org/obo/GO_1905533 GO:0090735 biolink:BiologicalProcess DNA repair complex assembly The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex. go-plus.json http://purl.obolibrary.org/obo/GO_0090735 GO:1905534 biolink:BiologicalProcess positive regulation of leucine import across plasma membrane Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane. go-plus.json up-regulation of L-leucine import into cell|positive regulation of leucine import into cell|activation of L-leucine import into cell|activation of leucine import into cell|up-regulation of leucine import into cell|positive regulation of L-leucine import into cell|up regulation of L-leucine import into cell|up regulation of leucine import into cell|upregulation of L-leucine import into cell|upregulation of leucine import into cell http://purl.obolibrary.org/obo/GO_1905534 GO:0090732 biolink:CellularComponent cofilin-actin rod A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers. go-plus.json http://purl.obolibrary.org/obo/GO_0090732 GO:1905535 biolink:BiologicalProcess regulation of eukaryotic translation initiation factor 4F complex assembly Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly. go-plus.json regulation of eIF-4F assembly|regulation of eIF4F assembly http://purl.obolibrary.org/obo/GO_1905535 GO:2000990 biolink:BiologicalProcess positive regulation of hemicellulose catabolic process Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process. go-plus.json positive regulation of hemicellulose catabolism http://purl.obolibrary.org/obo/GO_2000990 GO:0090733 biolink:CellularComponent tenascin complex A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R. go-plus.json Tenascin-X|Tenascin-W|Tenascin-R|Tenascin-N|Tenascin-C http://purl.obolibrary.org/obo/GO_0090733 GO:2000991 biolink:BiologicalProcess regulation of galactomannan catabolic process Any process that modulates the frequency, rate or extent of galactomannan catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_2000991 GO:1905536 biolink:BiologicalProcess negative regulation of eukaryotic translation initiation factor 4F complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly. go-plus.json down regulation of eIF-4F assembly|downregulation of eIF-4F assembly|down-regulation of eukaryotic translation initiation factor 4F complex assembly|negative regulation of eIF4F assembly|down-regulation of eIF4F assembly|down-regulation of eIF-4F assembly|negative regulation of eIF-4F assembly|downregulation of eukaryotic translation initiation factor 4F complex assembly|downregulation of eIF4F assembly|inhibition of eIF-4F assembly|down regulation of eukaryotic translation initiation factor 4F complex assembly|inhibition of eukaryotic translation initiation factor 4F complex assembly|down regulation of eIF4F assembly|inhibition of eIF4F assembly http://purl.obolibrary.org/obo/GO_1905536 GO:1905537 biolink:BiologicalProcess positive regulation of eukaryotic translation initiation factor 4F complex assembly Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly. go-plus.json upregulation of eIF-4F assembly|up-regulation of eukaryotic translation initiation factor 4F complex assembly|activation of eukaryotic translation initiation factor 4F complex assembly|up-regulation of eIF4F assembly|activation of eIF4F assembly|up regulation of eIF-4F assembly|positive regulation of eIF-4F assembly|activation of eIF-4F assembly|positive regulation of eIF4F assembly|up regulation of eukaryotic translation initiation factor 4F complex assembly|up regulation of eIF4F assembly|up-regulation of eIF-4F assembly|upregulation of eukaryotic translation initiation factor 4F complex assembly|upregulation of eIF4F assembly http://purl.obolibrary.org/obo/GO_1905537 GO:2000992 biolink:BiologicalProcess negative regulation of galactomannan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_2000992 GO:2000993 biolink:BiologicalProcess positive regulation of galactomannan catabolic process Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_2000993 GO:0090736 biolink:MolecularActivity MATH domain binding Binding to a meprin and TRAF homology (MATH) domain. go-plus.json http://purl.obolibrary.org/obo/GO_0090736 GO:1905538 biolink:MolecularActivity polysome binding Binding to a polysome. go-plus.json polyribosome binding http://purl.obolibrary.org/obo/GO_1905538 GO:0090737 biolink:BiologicalProcess telomere maintenance via telomere trimming A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication. go-plus.json http://purl.obolibrary.org/obo/GO_0090737 GO:1905539 biolink:BiologicalProcess regulation of postsynapse to nucleus signaling pathway Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway. go-plus.json regulation of postsynaptic signaling to nucleus http://purl.obolibrary.org/obo/GO_1905539 goslim_synapse GO:2000994 biolink:BiologicalProcess regulation of mannan catabolic process Any process that modulates the frequency, rate or extent of mannan catabolic process. go-plus.json regulation of mannan catabolism|regulation of mannan degradation|regulation of mannan breakdown http://purl.obolibrary.org/obo/GO_2000994 NCBITaxon:4430 biolink:OrganismalEntity Nelumbo go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4430 UBERON:0008331 biolink:AnatomicalEntity clitoral smooth muscle A smooth muscle tissue that is part of a clitoris. go-plus.json clitoris smooth muscle http://purl.obolibrary.org/obo/UBERON_0008331 GO:0090730 biolink:CellularComponent Las1 complex A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448). go-plus.json Las1-Grc3-Rat1-Rai1 http://purl.obolibrary.org/obo/GO_0090730 GO:0051122 biolink:BiologicalProcess hepoxilin biosynthetic process The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology. go-plus.json hepoxilin anabolism|hepoxilin synthesis|hepoxilin formation|hepoxilin biosynthesis http://purl.obolibrary.org/obo/GO_0051122 GO:0090731 biolink:BiologicalProcess cellular response to very-low-density lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus. go-plus.json cellular response to VLDL particle stimulus http://purl.obolibrary.org/obo/GO_0090731 GO:0051123 biolink:BiologicalProcess RNA polymerase II preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. go-plus.json RNA polymerase II transcriptional preinitiation complex formation|RNA polymerase II transcriptional preinitiation complex assembly|RNA polymerase II transcription PIC biosynthesis|RNA polymerase II transcription PIC formation http://purl.obolibrary.org/obo/GO_0051123 GO:0051120 biolink:MolecularActivity hepoxilin A3 synthase activity Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3. Reactome:R-HSA-8942208|Reactome:R-HSA-2161794 go-plus.json http://purl.obolibrary.org/obo/GO_0051120 GO:0051121 biolink:BiologicalProcess hepoxilin metabolic process The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology. go-plus.json hepoxilin metabolism http://purl.obolibrary.org/obo/GO_0051121 GO:0051137 biolink:BiologicalProcess negative regulation of NK T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation. go-plus.json negative regulation of NK T lymphocyte differentiation|negative regulation of natural killer T cell differentiation|inhibition of NK T cell differentiation|negative regulation of NKT cell differentiation|negative regulation of natural T cell differentiation|negative regulation of NK T-cell differentiation|down regulation of NK T cell differentiation|negative regulation of NT cell differentiation|downregulation of NK T cell differentiation|negative regulation of NK T-lymphocyte differentiation|negative regulation of NK T cell development|down-regulation of NK T cell differentiation http://purl.obolibrary.org/obo/GO_0051137 GO:0075104 biolink:BiologicalProcess obsolete positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075104 GO:0051138 biolink:BiologicalProcess positive regulation of NK T cell differentiation Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation. go-plus.json up-regulation of NK T cell differentiation|positive regulation of NKT cell differentiation|positive regulation of NK T-cell differentiation|upregulation of NK T cell differentiation|positive regulation of NT cell differentiation|positive regulation of NK T-lymphocyte differentiation|positive regulation of natural T cell differentiation|up regulation of NK T cell differentiation|positive regulation of NK T cell development|activation of NK T cell differentiation|stimulation of NK T cell differentiation|positive regulation of NK T lymphocyte differentiation|positive regulation of natural killer T cell differentiation http://purl.obolibrary.org/obo/GO_0051138 GO:0075105 biolink:BiologicalProcess obsolete negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075105 GO:0051135 biolink:BiologicalProcess positive regulation of NK T cell activation Any process that activates or increases the frequency, rate or extent of natural killer T cell activation. go-plus.json upregulation of NK T cell activation|positive regulation of NK T-cell activation|positive regulation of NKT cell activation|stimulation of NK T cell activation|up-regulation of NK T cell activation|activation of NK T cell activation|positive regulation of natural killer T cell activation|positive regulation of NK T lymphocyte activation|up regulation of NK T cell activation|positive regulation of natural T cell activation|positive regulation of NK T-lymphocyte activation|positive regulation of NT cell activation http://purl.obolibrary.org/obo/GO_0051135 GO:0075106 biolink:BiologicalProcess obsolete modulation by symbiont of host adenylate cyclase activity OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json Modulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Modulation by symbiont of host ATP pyrophosphate-lyase activity|Modulation by symbiont of host adenyl cyclase activity|Modulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity|Modulation by symbiont of host adenylylcyclase activity|Modulation by symbiont of host cAMP generating peptide activity|Modulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Modulation by symbiont of host adenylyl cyclase activity http://purl.obolibrary.org/obo/GO_0075106 GO:0051136 biolink:BiologicalProcess regulation of NK T cell differentiation Any process that modulates the frequency, rate or extent of natural killer T cell differentiation. go-plus.json regulation of NK T-cell differentiation|regulation of NT cell differentiation|regulation of NK T-lymphocyte differentiation|regulation of NK T cell development|regulation of NKT cell differentiation|regulation of NK T lymphocyte differentiation|regulation of natural killer T cell differentiation|regulation of natural T cell differentiation http://purl.obolibrary.org/obo/GO_0051136 GO:0075107 biolink:BiologicalProcess obsolete positive regulation by symbiont of host adenylate cyclase activity OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host adenylyl cyclase activity|positive regulation by symbiont of host adenylylcyclase activity|positive regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|positive regulation by symbiont of host adenyl cyclase activity|positive regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity http://purl.obolibrary.org/obo/GO_0075107 GO:0075108 biolink:BiologicalProcess obsolete negative regulation by symbiont of host adenylate cyclase activity OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json Negative regulation by symbiont of host adenylyl cyclase activity|Negative regulation by symbiont of host adenylylcyclase activity|Negative regulation by symbiont of host cAMP generating peptide activity|Negative regulation by symbiont of host adenyl cyclase activity|Negative regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Negative regulation by symbiont of host ATP pyrophosphate-lyase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity http://purl.obolibrary.org/obo/GO_0075108 CHEBI:26125 biolink:ChemicalSubstance phytosterols go-plus.json http://purl.obolibrary.org/obo/CHEBI_26125 GO:0075109 biolink:BiologicalProcess modulation by symbiont of host receptor-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075109 GO:0051139 biolink:MolecularActivity metal ion:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in). Reactome:R-HSA-435171 go-plus.json metal ion:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0051139 CHEBI:26127 biolink:ChemicalSubstance phytylnaphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26127 NCBITaxon:63363 biolink:OrganismalEntity Aquifex aeolicus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_63363 CHEBI:26124 biolink:ChemicalSubstance phytosteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26124 GO:1905550 biolink:BiologicalProcess regulation of protein localization to endoplasmic reticulum Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum. go-plus.json regulation of protein localization in ER|regulation of protein localization in endoplasmic reticulum|regulation of protein localisation in endoplasmic reticulum http://purl.obolibrary.org/obo/GO_1905550 GO:1905551 biolink:BiologicalProcess negative regulation of protein localization to endoplasmic reticulum Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum. go-plus.json inhibition of protein localisation in endoplasmic reticulum|downregulation of protein localization in ER|inhibition of protein localization to endoplasmic reticulum|down regulation of protein localization in ER|inhibition of protein localization in ER|down regulation of protein localization in endoplasmic reticulum|downregulation of protein localization in endoplasmic reticulum|down regulation of protein localisation in endoplasmic reticulum|down regulation of protein localization to endoplasmic reticulum|downregulation of protein localisation in endoplasmic reticulum|down-regulation of protein localization in endoplasmic reticulum|negative regulation of protein localization in endoplasmic reticulum|downregulation of protein localization to endoplasmic reticulum|down-regulation of protein localization in ER|negative regulation of protein localization in ER|inhibition of protein localization in endoplasmic reticulum|down-regulation of protein localisation in endoplasmic reticulum|negative regulation of protein localisation in endoplasmic reticulum|down-regulation of protein localization to endoplasmic reticulum http://purl.obolibrary.org/obo/GO_1905551 GO:0089710 biolink:MolecularActivity endocytic targeting sequence binding Binding to a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits. go-plus.json http://purl.obolibrary.org/obo/GO_0089710 GO:1905552 biolink:BiologicalProcess positive regulation of protein localization to endoplasmic reticulum Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum. go-plus.json up-regulation of protein localisation in endoplasmic reticulum|upregulation of protein localization in endoplasmic reticulum|up-regulation of protein localization to endoplasmic reticulum|upregulation of protein localization in ER|upregulation of protein localisation in endoplasmic reticulum|up regulation of protein localization in endoplasmic reticulum|upregulation of protein localization to endoplasmic reticulum|positive regulation of protein localization in endoplasmic reticulum|activation of protein localization in endoplasmic reticulum|up-regulation of protein localization in ER|activation of protein localization in ER|up regulation of protein localisation in endoplasmic reticulum|activation of protein localisation in endoplasmic reticulum|positive regulation of protein localisation in endoplasmic reticulum|up regulation of protein localization to endoplasmic reticulum|activation of protein localization to endoplasmic reticulum|up-regulation of protein localization in endoplasmic reticulum|positive regulation of protein localization in ER|up regulation of protein localization in ER http://purl.obolibrary.org/obo/GO_1905552 GO:1905553 biolink:BiologicalProcess regulation of blood vessel branching Any process that modulates the frequency, rate or extent of blood vessel branching. go-plus.json regulation of branching involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1905553 GO:0089711 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0089711 CHEBI:26120 biolink:ChemicalSubstance phytofluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_26120 chebi_ph7_3 GO:1905543 biolink:CellularComponent interleukin-15 receptor complex A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors. go-plus.json interleukin-15-receptor complex|IL15-receptor complex|IL-15-receptor complex|IL15 receptor complex|IL-15 receptor complex http://purl.obolibrary.org/obo/GO_1905543 GO:0089712 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0089712 GO:0090701 biolink:BiologicalProcess specification of plant organ identity The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0090701 GO:0089713 biolink:CellularComponent Cbf1-Met4-Met28 complex A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation. go-plus.json http://purl.obolibrary.org/obo/GO_0089713 GO:1905544 biolink:BiologicalProcess L-methionine import across plasma membrane The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-methionine import into cell http://purl.obolibrary.org/obo/GO_1905544 GO:0090702 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090702 GO:1905545 biolink:BiologicalProcess obsolete negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron. go-plus.json negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron http://purl.obolibrary.org/obo/GO_1905545 GO:0089714 biolink:MolecularActivity UDP-N-acetyl-D-mannosamine dehydrogenase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+. RHEA:25780|EC:1.1.1.336 go-plus.json http://purl.obolibrary.org/obo/GO_0089714 GO:0090700 biolink:BiologicalProcess maintenance of plant organ identity The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0090700 GO:0089715 biolink:MolecularActivity tRNA m6t6A37 methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine. MetaCyc:RXN0-7114 go-plus.json http://purl.obolibrary.org/obo/GO_0089715 GO:1905546 biolink:BiologicalProcess cellular response to phenylpropanoid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905546 GO:0089716 biolink:CellularComponent Pip2-Oaf1 complex A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0089716 GO:0090705 biolink:CellularComponent trichome papilla A plant cell papilla that is part of a trichome cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090705 GO:1905547 biolink:BiologicalProcess obsolete regulation of subtelomeric heterochromatin assembly OBSOLETE. Any process that modulates the frequency, rate or extent of subtelomeric heterochromatin assembly. go-plus.json regulation of telomeric heterochromatin formation|regulation of telomeric heterochromatin assembly http://purl.obolibrary.org/obo/GO_1905547 GO:1905548 biolink:BiologicalProcess obsolete negative regulation of subtelomeric heterochromatin assembly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of subtelomeric heterochromatin assembly. go-plus.json down-regulation of telomeric heterochromatin assembly|negative regulation of telomeric heterochromatin formation|down-regulation of telomeric heterochromatin formation|inhibition of telomeric heterochromatin formation|downregulation of telomeric heterochromatin assembly|inhibition of telomeric heterochromatin assembly|down regulation of telomeric heterochromatin assembly|negative regulation of telomeric heterochromatin assembly|down regulation of telomeric heterochromatin formation|downregulation of telomeric heterochromatin formation http://purl.obolibrary.org/obo/GO_1905548 GO:0089717 biolink:CellularComponent spanning component of membrane The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089717 GO:0090706 biolink:BiologicalProcess specification of plant organ position The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ. go-plus.json http://purl.obolibrary.org/obo/GO_0090706 GO:1905549 biolink:BiologicalProcess obsolete positive regulation of subtelomeric heterochromatin assembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of subtelomeric heterochromatin assembly. go-plus.json positive regulation of telomeric heterochromatin formation|up regulation of telomeric heterochromatin assembly|up-regulation of telomeric heterochromatin formation|upregulation of telomeric heterochromatin assembly|upregulation of telomeric heterochromatin formation|positive regulation of telomeric heterochromatin assembly|activation of telomeric heterochromatin assembly|activation of telomeric heterochromatin formation|up-regulation of telomeric heterochromatin assembly|up regulation of telomeric heterochromatin formation http://purl.obolibrary.org/obo/GO_1905549 GO:0089718 biolink:BiologicalProcess amino acid import across plasma membrane The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json amino acid import into cell|L-amino acid uptake|amino acid transmembrane import|L-amino acid import http://purl.obolibrary.org/obo/GO_0089718 GO:0090703 biolink:BiologicalProcess obsolete triplex DNA unwinding OBSOLETE. The process by which a three-stranded D-loop DNA is unwound or 'melted'. go-plus.json http://purl.obolibrary.org/obo/GO_0090703 GO:0090704 biolink:MolecularActivity nicotinate-O-glucosyltransferase activity Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP. go-plus.json http://purl.obolibrary.org/obo/GO_0090704 GO:0089719 biolink:MolecularActivity RHG protein domain binding Binding to an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif). go-plus.json inhibitor of apoptosis binding domain binding|RHG domain binding|reaper hid grim domain binding|iap binding domain binding http://purl.obolibrary.org/obo/GO_0089719 GO:0051130 biolink:BiologicalProcess positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. go-plus.json positive regulation of cellular component organization and biogenesis|up-regulation of cell organization|upregulation of cell organization|positive regulation of cell organisation|up regulation of cell organization|activation of cell organization|stimulation of cell organization http://purl.obolibrary.org/obo/GO_0051130 GO:0051133 biolink:BiologicalProcess regulation of NK T cell activation Any process that modulates the frequency, rate or extent of natural killer T cell activation. go-plus.json regulation of NK T-lymphocyte activation|regulation of NT cell activation|regulation of NK T-cell activation|regulation of natural T cell activation|regulation of natural killer T cell activation|regulation of NK T lymphocyte activation|regulation of NKT cell activation http://purl.obolibrary.org/obo/GO_0051133 GO:0075100 biolink:BiologicalProcess obsolete positive regulation by host of symbiont protein kinase-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075100 GO:0051134 biolink:BiologicalProcess negative regulation of NK T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation. go-plus.json negative regulation of natural T cell activation|negative regulation of NKT cell activation|negative regulation of natural killer T cell activation|negative regulation of NK T lymphocyte activation|down-regulation of NK T cell activation|negative regulation of NK T-lymphocyte activation|downregulation of NK T cell activation|negative regulation of NT cell activation|down regulation of NK T cell activation|negative regulation of NK T-cell activation|inhibition of NK T cell activation http://purl.obolibrary.org/obo/GO_0051134 GO:0075101 biolink:BiologicalProcess obsolete negative regulation by host of symbiont protein kinase-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075101 GO:0051131 biolink:BiologicalProcess chaperone-mediated protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. go-plus.json cellular chaperone-mediated protein complex assembly|chaperone activity|protein complex assembly, multichaperone pathway http://purl.obolibrary.org/obo/GO_0051131 GO:0075102 biolink:BiologicalProcess obsolete negative regulation by host of symbiont MAP kinase-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont MAP kinase-mediated signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075102 GO:0051132 biolink:BiologicalProcess NK T cell activation The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json natural T cell activation|NKT cell activation|natural killer T cell activation|NK T lymphocyte activation|NK T-lymphocyte activation|NT cell activation|NK T-cell activation http://purl.obolibrary.org/obo/GO_0051132 UBERON:0008324 biolink:AnatomicalEntity erectile tissue with numerous vascular spaces that may become engorged with blood go-plus.json http://purl.obolibrary.org/obo/UBERON_0008324 GO:0075103 biolink:BiologicalProcess obsolete modulation by host of symbiont calcium or calmodulin-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by host of symbiont Ca++ or calmodulin-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075103 GO:0051148 biolink:BiologicalProcess negative regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. go-plus.json downregulation of muscle cell differentiation|down-regulation of muscle cell differentiation|inhibition of muscle cell differentiation|down regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051148 GO:0051149 biolink:BiologicalProcess positive regulation of muscle cell differentiation Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. go-plus.json up regulation of muscle cell differentiation|activation of muscle cell differentiation|stimulation of muscle cell differentiation|up-regulation of muscle cell differentiation|upregulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051149 GO:0051146 biolink:BiologicalProcess striated muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. go-plus.json voluntary muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051146 GO:0051147 biolink:BiologicalProcess regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0051147 GO:0090709 biolink:BiologicalProcess regulation of timing of plant organ formation Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development. go-plus.json http://purl.obolibrary.org/obo/GO_0090709 CHEBI:26133 biolink:ChemicalSubstance pinane monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26133 GO:0090707 biolink:BiologicalProcess establishment of plant organ orientation The process that determines the orientation of a plant organ or tissue with reference to an axis. go-plus.json http://purl.obolibrary.org/obo/GO_0090707 GO:1905560 biolink:BiologicalProcess negative regulation of kinetochore assembly Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly. go-plus.json down-regulation of centromere/kinetochore complex maturation|negative regulation of centromere/kinetochore complex maturation|down regulation of chromosome-kinetochore attachment|down-regulation of kinetochore formation|negative regulation of centromere and kinetochore complex maturation|down-regulation of centromere and kinetochore complex maturation|negative regulation of kinetochore formation|downregulation of chromosome-kinetochore attachment|down-regulation of kinetochore assembly|inhibition of centromere/kinetochore complex maturation|negative regulation of chromosome-kinetochore attachment|down-regulation of chromosome-kinetochore attachment|inhibition of centromere and kinetochore complex maturation|inhibition of kinetochore formation|down regulation of centromere/kinetochore complex maturation|downregulation of kinetochore assembly|downregulation of centromere/kinetochore complex maturation|down regulation of kinetochore assembly|down regulation of kinetochore formation|down regulation of centromere and kinetochore complex maturation|inhibition of kinetochore assembly|inhibition of chromosome-kinetochore attachment|downregulation of kinetochore formation|down regulation of kinetochore biogenesis|downregulation of centromere and kinetochore complex maturation http://purl.obolibrary.org/obo/GO_1905560 GO:0090708 biolink:BiologicalProcess specification of plant organ axis polarity The process in which the polarity of a plant organ axis is specified. go-plus.json http://purl.obolibrary.org/obo/GO_0090708 GO:1905561 biolink:BiologicalProcess positive regulation of kinetochore assembly Any process that activates or increases the frequency, rate or extent of kinetochore assembly. go-plus.json upregulation of chromosome-kinetochore attachment|up regulation of kinetochore formation|up regulation of centromere and kinetochore complex maturation|activation of centromere/kinetochore complex maturation|positive regulation of kinetochore formation|positive regulation of centromere and kinetochore complex maturation|up-regulation of kinetochore assembly|activation of kinetochore assembly|activation of centromere and kinetochore complex maturation|up-regulation of centromere/kinetochore complex maturation|activation of kinetochore formation|up regulation of chromosome-kinetochore attachment|positive regulation of chromosome-kinetochore attachment|up-regulation of kinetochore formation|up-regulation of centromere and kinetochore complex maturation|upregulation of centromere/kinetochore complex maturation|activation of chromosome-kinetochore attachment|up regulation of kinetochore assembly|upregulation of centromere and kinetochore complex maturation|up-regulation of chromosome-kinetochore attachment|upregulation of kinetochore formation|up regulation of centromere/kinetochore complex maturation|upregulation of kinetochore assembly|positive regulation of centromere/kinetochore complex maturation http://purl.obolibrary.org/obo/GO_1905561 GO:1905562 biolink:BiologicalProcess regulation of vascular endothelial cell proliferation Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_1905562 GO:0089720 biolink:MolecularActivity caspase binding Binding to a caspase family protein. go-plus.json http://purl.obolibrary.org/obo/GO_0089720 GO:1905563 biolink:BiologicalProcess negative regulation of vascular endothelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. go-plus.json inhibition of vascular endothelial cell proliferation|down regulation of vascular endothelial cell proliferation|downregulation of vascular endothelial cell proliferation|down-regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_1905563 GO:0089721 biolink:MolecularActivity phosphoenolpyruvate transmembrane transporter activity Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0089721 CHEBI:26130 biolink:ChemicalSubstance biological pigment go-plus.json http://purl.obolibrary.org/obo/CHEBI_26130 GO:1905564 biolink:BiologicalProcess positive regulation of vascular endothelial cell proliferation Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. go-plus.json up-regulation of vascular endothelial cell proliferation|upregulation of vascular endothelial cell proliferation|up regulation of vascular endothelial cell proliferation|activation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_1905564 GO:0089722 biolink:BiologicalProcess phosphoenolpyruvate transmembrane transport The directed movement of phosphoenolpytuvate across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089722 GO:1905554 biolink:BiologicalProcess negative regulation of vessel branching Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. go-plus.json downregulation of branching involved in blood vessel morphogenesis|down regulation of branching involved in blood vessel morphogenesis|inhibition of branching involved in blood vessel morphogenesis|down regulation of patterning of blood vessels|downregulation of patterning of blood vessels|down-regulation of patterning of blood vessels|negative regulation of branching involved in blood vessel morphogenesis|down-regulation of branching involved in blood vessel morphogenesis|inhibition of patterning of blood vessels http://purl.obolibrary.org/obo/GO_1905554 GO:0090712 biolink:CellularComponent basal pole of outer hair cell The end of the outer hair cell which receives and transmits neural signals. go-plus.json http://purl.obolibrary.org/obo/GO_0090712 GO:0090713 biolink:BiologicalProcess immunological memory process Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. go-plus.json http://purl.obolibrary.org/obo/GO_0090713 GO:1905555 biolink:BiologicalProcess positive regulation of blood vessel branching Any process that activates or increases the frequency, rate or extent of blood vessel branching. go-plus.json upregulation of patterning of blood vessels|upregulation of branching involved in blood vessel morphogenesis|up regulation of patterning of blood vessels|up-regulation of branching involved in blood vessel morphogenesis|activation of branching involved in blood vessel morphogenesis|activation of patterning of blood vessels|positive regulation of branching involved in blood vessel morphogenesis|up-regulation of patterning of blood vessels|up regulation of branching involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1905555 GO:1905556 biolink:BiologicalProcess ciliary vesicle assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane. go-plus.json primary ciliary vesicle formation|CV assembly|ciliary vesicle formation|primary ciliary vesicle assembly|CV formation http://purl.obolibrary.org/obo/GO_1905556 GO:0090710 biolink:MolecularActivity phosphomevalonate decarboxylase activity Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0090710 GO:0090711 biolink:MolecularActivity FMN hydrolase activity Catalysis of the reaction: FMN + H2O = riboflavin + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0090711 GO:1905557 biolink:BiologicalProcess regulation of mitotic nuclear envelope disassembly Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly. go-plus.json regulation of mitotic nuclear envelope degradation|regulation of mitotic nuclear envelope catabolism|regulation of mitotic nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_1905557 GO:1905558 biolink:BiologicalProcess negative regulation of mitotic nuclear envelope disassembly Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly. go-plus.json inhibition of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope disassembly|negative regulation of mitotic nuclear envelope degradation|inhibition of mitotic nuclear envelope disassembly|down-regulation of mitotic nuclear envelope degradation|down-regulation of mitotic nuclear envelope breakdown|negative regulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope degradation|down regulation of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope degradation|inhibition of mitotic nuclear envelope degradation|downregulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope breakdown|down-regulation of mitotic nuclear envelope disassembly|inhibition of mitotic nuclear envelope breakdown|negative regulation of mitotic nuclear envelope catabolism|down-regulation of mitotic nuclear envelope catabolism|downregulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_1905558 GO:0090716 biolink:BiologicalProcess adaptive immune memory response An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response. go-plus.json http://purl.obolibrary.org/obo/GO_0090716 GO:0090717 biolink:BiologicalProcess adaptive immune memory response involving T cells and B cells An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response. go-plus.json http://purl.obolibrary.org/obo/GO_0090717 GO:1905559 biolink:BiologicalProcess positive regulation of mitotic nuclear envelope disassembly Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly. go-plus.json activation of mitotic nuclear envelope breakdown|up-regulation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope disassembly|positive regulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope degradation|upregulation of mitotic nuclear envelope catabolism|positive regulation of mitotic nuclear envelope breakdown|up regulation of mitotic nuclear envelope breakdown|up-regulation of mitotic nuclear envelope disassembly|activation of mitotic nuclear envelope disassembly|upregulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope catabolism|activation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope breakdown|positive regulation of mitotic nuclear envelope catabolism|up regulation of mitotic nuclear envelope disassembly|up-regulation of mitotic nuclear envelope degradation|activation of mitotic nuclear envelope degradation|up-regulation of mitotic nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_1905559 GO:0090714 biolink:BiologicalProcess innate immunity memory response An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0090714 GO:0090715 biolink:BiologicalProcess immunological memory formation process Any immunological memory process that can contribute to the formation of immunological memory. go-plus.json http://purl.obolibrary.org/obo/GO_0090715 GO:0051140 biolink:BiologicalProcess regulation of NK T cell proliferation Any process that modulates the frequency, rate or extent of natural killer T cell proliferation. go-plus.json regulation of NK T-cell proliferation|regulation of NT cell proliferation|regulation of NK T-lymphocyte proliferation|regulation of NKT cell proliferation|regulation of NK T lymphocyte proliferation|regulation of natural killer T cell proliferation|regulation of natural T cell proliferation http://purl.obolibrary.org/obo/GO_0051140 GO:0051141 biolink:BiologicalProcess negative regulation of NK T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation. go-plus.json down-regulation of NK T cell proliferation|negative regulation of NK T lymphocyte proliferation|negative regulation of natural killer T cell proliferation|inhibition of NK T cell proliferation|negative regulation of NKT cell proliferation|negative regulation of natural T cell proliferation|down regulation of NK T cell proliferation|negative regulation of NK T-cell proliferation|negative regulation of NT cell proliferation|downregulation of NK T cell proliferation|negative regulation of NK T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051141 GO:0051144 biolink:BiologicalProcess propanediol catabolic process The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH. go-plus.json propanediol degradation|1,2-dihydroxypropane catabolic process|propanediol catabolism|propanediol breakdown|1,2-dihydroxypropane catabolism|propylene glycol catabolism|propylene glycol catabolic process http://purl.obolibrary.org/obo/GO_0051144 UBERON:0008310 biolink:AnatomicalEntity nasopharyngeal gland A gland that is part of a nasopharynx. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008310 GO:0051145 biolink:BiologicalProcess smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. go-plus.json nonstriated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 GO:0051142 biolink:BiologicalProcess positive regulation of NK T cell proliferation Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation. go-plus.json stimulation of NK T cell proliferation|positive regulation of NK T lymphocyte proliferation|positive regulation of natural killer T cell proliferation|up-regulation of NK T cell proliferation|positive regulation of NKT cell proliferation|positive regulation of NK T-cell proliferation|upregulation of NK T cell proliferation|positive regulation of NT cell proliferation|positive regulation of NK T-lymphocyte proliferation|positive regulation of natural T cell proliferation|up regulation of NK T cell proliferation|activation of NK T cell proliferation http://purl.obolibrary.org/obo/GO_0051142 GO:0051143 biolink:BiologicalProcess propanediol metabolic process The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items. go-plus.json propanediol metabolism|1,2-dihydroxypropane metabolism|propylene glycol metabolic process|propylene glycol metabolism|1,2-dihydroxypropane metabolic process http://purl.obolibrary.org/obo/GO_0051143 GO:2000948 biolink:BiologicalProcess regulation of xyloglucan metabolic process Any process that modulates the frequency, rate or extent of xyloglucan metabolic process. go-plus.json regulation of xyloglucan metabolism http://purl.obolibrary.org/obo/GO_2000948 GO:0051159 biolink:BiologicalProcess D-arabitol catabolic process The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. go-plus.json D-arabitol catabolism|D-arabitol degradation|D-arabitol breakdown http://purl.obolibrary.org/obo/GO_0051159 GO:0075126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075126 GO:2000949 biolink:BiologicalProcess negative regulation of xyloglucan metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process. go-plus.json negative regulation of xyloglucan metabolism http://purl.obolibrary.org/obo/GO_2000949 GO:0075127 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075127 GO:0051157 biolink:BiologicalProcess arabitol catabolic process The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. go-plus.json arabitol degradation|arabitol breakdown|arabitol catabolism|arabitol utilization http://purl.obolibrary.org/obo/GO_0051157 GO:0110058 biolink:BiologicalProcess positive regulation of blood vessel endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0110058 GO:0075128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075128 GO:0051158 biolink:BiologicalProcess L-arabitol catabolic process The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. go-plus.json L-arabitol degradation|L-arabitol breakdown|L-arabitol catabolism http://purl.obolibrary.org/obo/GO_0051158 GO:0110059 biolink:BiologicalProcess negative regulation of blood vessel endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0110059 GO:0075129 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075129 GO:0110056 biolink:BiologicalProcess positive regulation of actin filament annealing Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0110056 GO:0110057 biolink:BiologicalProcess regulation of blood vessel endothelial cell differentiation Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0110057 GO:0110054 biolink:BiologicalProcess regulation of actin filament annealing Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0110054 GO:0110055 biolink:BiologicalProcess negative regulation of actin filament annealing Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0110055 CHEBI:26106 biolink:ChemicalSubstance phylloquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_26106 GO:2000940 biolink:BiologicalProcess negative regulation of plant-type cell wall cellulose catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process. go-plus.json negative regulation of plant-type cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_2000940 GO:0110052 biolink:BiologicalProcess toxic metabolite repair A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites. go-plus.json http://purl.obolibrary.org/obo/GO_0110052 GO:0110053 biolink:BiologicalProcess regulation of actin filament organization Any process that modulates the frequency, rate or extent of actin filament organization. go-plus.json http://purl.obolibrary.org/obo/GO_0110053 GO:2000941 biolink:BiologicalProcess positive regulation of plant-type cell wall cellulose catabolic process Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process. go-plus.json positive regulation of plant-type cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_2000941 GO:1905570 biolink:BiologicalProcess positive regulation of ferrichrome biosynthetic process Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process. go-plus.json up-regulation of ferrichrome formation|upregulation of ferrichrome anabolism|up-regulation of ferrichrome biosynthesis|up-regulation of ferrichrome biosynthetic process|activation of ferrichrome biosynthetic process|activation of ferrichrome biosynthetic process, peptide formation|activation of ferrichrome biosynthesis|activation of ferrichrome biosynthetic process, peptide modification|upregulation of ferrichrome synthesis|upregulation of ferrichrome formation|up-regulation of ferrichrome biosynthetic process, peptide formation|positive regulation of ferrichrome biosynthetic process, peptide modification|up regulation of ferrichrome biosynthetic process, peptide modification|up regulation of ferrichrome anabolism|positive regulation of ferrichrome anabolism|positive regulation of ferrichrome biosynthesis|activation of ferrichrome anabolism|up regulation of ferrichrome biosynthesis|up regulation of ferrichrome synthesis|up regulation of ferrichrome biosynthetic process|positive regulation of ferrichrome synthesis|activation of ferrichrome synthesis|upregulation of ferrichrome biosynthetic process, peptide formation|up regulation of ferrichrome formation|positive regulation of ferrichrome formation|activation of ferrichrome formation|upregulation of ferrichrome biosynthetic process, peptide modification|up-regulation of ferrichrome anabolism|upregulation of ferrichrome biosynthetic process|upregulation of ferrichrome biosynthesis|up regulation of ferrichrome biosynthetic process, peptide formation|up-regulation of ferrichrome synthesis|up-regulation of ferrichrome biosynthetic process, peptide modification|positive regulation of ferrichrome biosynthetic process, peptide formation http://purl.obolibrary.org/obo/GO_1905570 GO:0110050 biolink:MolecularActivity deaminated glutathione amidase activity Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine. go-plus.json http://purl.obolibrary.org/obo/GO_0110050 GO:2000942 biolink:BiologicalProcess regulation of amylopectin metabolic process Any process that modulates the frequency, rate or extent of amylopectin metabolic process. go-plus.json regulation of Amylopectin metabolism http://purl.obolibrary.org/obo/GO_2000942 GO:0110051 biolink:BiologicalProcess metabolite repair A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites. go-plus.json http://purl.obolibrary.org/obo/GO_0110051 GO:1905571 biolink:CellularComponent interleukin-10 receptor complex A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors. go-plus.json interleukin-10-receptor complex|IL-10-receptor complex|IL10 receptor complex|IL-10 receptor complex http://purl.obolibrary.org/obo/GO_1905571 GO:2000943 biolink:BiologicalProcess negative regulation of amylopectin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process. go-plus.json negative regulation of Amylopectin metabolism http://purl.obolibrary.org/obo/GO_2000943 GO:1905572 biolink:BiologicalProcess ganglioside GM1 transport to membrane The directed movement of ganglioside GM1 to membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905572 GO:2000944 biolink:BiologicalProcess positive regulation of amylopectin metabolic process Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process. go-plus.json positive regulation of Amylopectin metabolism http://purl.obolibrary.org/obo/GO_2000944 GO:2000945 biolink:BiologicalProcess regulation of amylopectin catabolic process Any process that modulates the frequency, rate or extent of amylopectin catabolic process. go-plus.json regulation of Amylopectin catabolism http://purl.obolibrary.org/obo/GO_2000945 GO:1905573 biolink:MolecularActivity ganglioside GM1 binding Binding to ganglioside GM1. go-plus.json http://purl.obolibrary.org/obo/GO_1905573 GO:2000946 biolink:BiologicalProcess negative regulation of amylopectin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process. go-plus.json negative regulation of Amylopectin catabolism http://purl.obolibrary.org/obo/GO_2000946 GO:1905574 biolink:MolecularActivity ganglioside GM2 binding Binding to ganglioside GM2. go-plus.json http://purl.obolibrary.org/obo/GO_1905574 GO:2000947 biolink:BiologicalProcess positive regulation of amylopectin catabolic process Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process. go-plus.json positive regulation of Amylopectin catabolism http://purl.obolibrary.org/obo/GO_2000947 GO:1905575 biolink:MolecularActivity ganglioside GM3 binding Binding to ganglioside GM3. go-plus.json http://purl.obolibrary.org/obo/GO_1905575 GO:1905565 biolink:BiologicalProcess obsolete regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport OBSOLETE. Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. go-plus.json regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of LDL http://purl.obolibrary.org/obo/GO_1905565 GO:1905566 biolink:BiologicalProcess obsolete negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. go-plus.json down regulation of receptor-mediated endocytosis of LDL|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|inhibition of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL http://purl.obolibrary.org/obo/GO_1905566 GO:1905567 biolink:BiologicalProcess obsolete positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport OBSOLETE. Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. go-plus.json activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|activation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport http://purl.obolibrary.org/obo/GO_1905567 GO:1905568 biolink:BiologicalProcess regulation of ferrichrome biosynthetic process Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process. go-plus.json regulation of ferrichrome synthesis|regulation of ferrichrome formation|regulation of ferrichrome biosynthetic process, peptide modification|regulation of ferrichrome biosynthesis|regulation of ferrichrome biosynthetic process, peptide formation|regulation of ferrichrome anabolism http://purl.obolibrary.org/obo/GO_1905568 GO:1905569 biolink:BiologicalProcess negative regulation of ferrichrome biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process. go-plus.json negative regulation of ferrichrome biosynthesis|down-regulation of ferrichrome biosynthesis|down-regulation of ferrichrome biosynthetic process|down regulation of ferrichrome formation|downregulation of ferrichrome synthesis|downregulation of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome biosynthetic process, peptide formation|downregulation of ferrichrome formation|down-regulation of ferrichrome anabolism|negative regulation of ferrichrome anabolism|downregulation of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process, peptide modification|downregulation of ferrichrome biosynthetic process|down regulation of ferrichrome biosynthetic process, peptide formation|down-regulation of ferrichrome synthesis|negative regulation of ferrichrome synthesis|down regulation of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process|down-regulation of ferrichrome formation|inhibition of ferrichrome biosynthesis|inhibition of ferrichrome biosynthetic process|negative regulation of ferrichrome formation|inhibition of ferrichrome anabolism|downregulation of ferrichrome biosynthetic process, peptide formation|inhibition of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome synthesis|inhibition of ferrichrome formation|negative regulation of ferrichrome biosynthetic process, peptide formation|down-regulation of ferrichrome biosynthetic process, peptide formation|down regulation of ferrichrome anabolism|down-regulation of ferrichrome biosynthetic process, peptide modification|negative regulation of ferrichrome biosynthetic process, peptide modification|down regulation of ferrichrome synthesis|downregulation of ferrichrome anabolism http://purl.obolibrary.org/obo/GO_1905569 CHEBI:16777 biolink:ChemicalSubstance berbamunine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16777 CHEBI:16778 biolink:ChemicalSubstance apigenin 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16778 CHEBI:16775 biolink:ChemicalSubstance 3-aci-nitropropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16775 CHEBI:16776 biolink:ChemicalSubstance tabersonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16776 GO:0051151 biolink:BiologicalProcess negative regulation of smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. go-plus.json down-regulation of smooth muscle cell differentiation|downregulation of smooth muscle cell differentiation|down regulation of smooth muscle cell differentiation|inhibition of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051151 CHEBI:16773 biolink:ChemicalSubstance trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16773 GO:0051152 biolink:BiologicalProcess positive regulation of smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. go-plus.json stimulation of smooth muscle cell differentiation|up-regulation of smooth muscle cell differentiation|activation of smooth muscle cell differentiation|up regulation of smooth muscle cell differentiation|upregulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051152 CHEBI:16774 biolink:ChemicalSubstance (2-cis,6-trans)-farnesol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16774 chebi_ph7_3 GO:0075120 biolink:BiologicalProcess suppression by symbiont of host G protein-coupled receptor signal transduction Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host G-protein coupled receptor protein signal transduction|negative regulation by symbiont of host G protein-coupled receptor signal transduction|negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit|negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit|negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit http://purl.obolibrary.org/obo/GO_0075120 CHEBI:16771 biolink:ChemicalSubstance adenosine 5'-phosphoramidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16771 GO:0051150 biolink:BiologicalProcess regulation of smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0051150 GO:0075121 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075121 CHEBI:16772 biolink:ChemicalSubstance xylitol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16772 GO:0051155 biolink:BiologicalProcess positive regulation of striated muscle cell differentiation Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. go-plus.json upregulation of striated muscle cell differentiation|stimulation of striated muscle cell differentiation|up-regulation of striated muscle cell differentiation|activation of striated muscle cell differentiation|up regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051155 GO:0075122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075122 GO:0051156 biolink:BiologicalProcess glucose 6-phosphate metabolic process The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6. go-plus.json glucose 6-phosphate utilization|glucose 6-phosphate metabolism http://purl.obolibrary.org/obo/GO_0051156 GO:0075123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075123 CHEBI:16770 biolink:ChemicalSubstance N(5)-(L-1-carboxyethyl)-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16770 GO:0075124 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075124 GO:0051153 biolink:BiologicalProcess regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0051153 GO:0051154 biolink:BiologicalProcess negative regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. go-plus.json inhibition of striated muscle cell differentiation|down-regulation of striated muscle cell differentiation|downregulation of striated muscle cell differentiation|down regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051154 GO:0075125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075125 GO:2000959 biolink:BiologicalProcess positive regulation of cyclodextrin catabolic process Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process. go-plus.json positive regulation of cyclodextrin catabolism http://purl.obolibrary.org/obo/GO_2000959 GO:0075115 biolink:BiologicalProcess obsolete modulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host transmembrane receptor-mediated cAMP signaling http://purl.obolibrary.org/obo/GO_0075115 GO:0099104 biolink:MolecularActivity potassium channel activator activity Binds to and increases the activity of a potassium channel, resulting in its opening. go-plus.json http://purl.obolibrary.org/obo/GO_0099104 CHEBI:26118 biolink:ChemicalSubstance phytoecdysteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26118 GO:0099105 biolink:BiologicalProcess ion channel modulating, G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel. go-plus.json ion channel modulating, G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0099105 GO:0075116 biolink:BiologicalProcess obsolete induction by symbiont of host transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host transmembrane receptor-mediated cAMP signaling|activation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|positive regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|stimulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|promotion by symbiont of host transmembrane receptor-mediated cAMP signal transduction|upregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction http://purl.obolibrary.org/obo/GO_0075116 CHEBI:26119 biolink:ChemicalSubstance phytoene go-plus.json http://purl.obolibrary.org/obo/CHEBI_26119 chebi_ph7_3 GO:0051168 biolink:BiologicalProcess nuclear export The directed movement of substances out of the nucleus. go-plus.json substance nuclear export|export from nucleus|nucleus export http://purl.obolibrary.org/obo/GO_0051168 GO:0075117 biolink:BiologicalProcess obsolete suppression by symbiont of host transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json downregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|negative regulation by symbiont of host transmembrane receptor-mediated cAMP signaling|inhibition by symbiont of host transmembrane receptor-mediated cAMP signal transduction http://purl.obolibrary.org/obo/GO_0075117 GO:0110069 biolink:BiologicalProcess syncytial embryo cellularization The separation of a syncytial embryo into individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0110069 GO:0099102 biolink:MolecularActivity G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential. go-plus.json http://purl.obolibrary.org/obo/GO_0099102 goslim_synapse GO:0075118 biolink:BiologicalProcess modulation by symbiont of host G protein-coupled receptor signal transduction Any process in which the symbiont modulates the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host signal transduction mediated by G-protein gamma subunit|modulation by symbiont of host signal transduction mediated by G-protein beta subunit|modulation by symbiont of host signal transduction mediated by G-protein alpha subunit|modulation by symbiont of host G-protein coupled receptor protein signal transduction http://purl.obolibrary.org/obo/GO_0075118 GO:0051169 biolink:BiologicalProcess nuclear transport The directed movement of substances into, out of, or within the nucleus. Wikipedia:Nuclear_transport go-plus.json nucleus transport http://purl.obolibrary.org/obo/GO_0051169 goslim_yeast GO:0099103 biolink:MolecularActivity channel activator activity Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. go-plus.json channel gating activity http://purl.obolibrary.org/obo/GO_0099103 GO:0075119 biolink:BiologicalProcess induction by symbiont of host G protein-coupled receptor signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit|positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit|positive regulation by symbiont of host G-protein coupled receptor protein signal transduction|positive regulation by symbiont of host G protein-coupled receptor signal transduction|positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit http://purl.obolibrary.org/obo/GO_0075119 GO:0110067 biolink:CellularComponent ammonium transmembrane transporter complex High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other. go-plus.json AMT1 complex http://purl.obolibrary.org/obo/GO_0110067 GO:0099100 biolink:MolecularActivity G-protein gated cation channel activity A cation channel activity that is gated by binding of a G-protein beta-gamma dimer. go-plus.json http://purl.obolibrary.org/obo/GO_0099100 GO:0099101 biolink:MolecularActivity G-protein gated potassium channel activity A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer. go-plus.json http://purl.obolibrary.org/obo/GO_0099101 CHEBI:26115 biolink:ChemicalSubstance phytoalexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26115 GO:0110068 biolink:MolecularActivity glucosylglycerate phosphorylase activity Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate. go-plus.json http://purl.obolibrary.org/obo/GO_0110068 GO:0110065 biolink:BiologicalProcess regulation of interphase mitotic telomere clustering Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase. go-plus.json regulation of mitotic telomere clustering during interphase http://purl.obolibrary.org/obo/GO_0110065 CHEBI:26116 biolink:ChemicalSubstance phytochromobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_26116 GO:0110066 biolink:BiologicalProcess negative regulation of interphase mitotic telomere clustering Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase. go-plus.json negative regulation of mitotic telomere clustering during interphase|telomere dispersion during interphase http://purl.obolibrary.org/obo/GO_0110066 GO:2000951 biolink:BiologicalProcess regulation of xyloglucan catabolic process Any process that modulates the frequency, rate or extent of xyloglucan catabolic process. go-plus.json regulation of xyloglucan catabolism http://purl.obolibrary.org/obo/GO_2000951 GO:0110063 biolink:BiologicalProcess positive regulation of angiotensin-activated signaling pathway Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0110063 GO:1905580 biolink:BiologicalProcess positive regulation of ERBB3 signaling pathway Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway. go-plus.json upregulation of ERBB3 signaling pathway|positive regulation of ERBB3 signalling pathway|positive regulation of HER3 signaling pathway|up regulation of HER3 signaling pathway|up regulation of ERBB3 signalling pathway|up-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of ERBB3 signaling pathway|upregulation of ERBB3 signalling pathway|upregulation of HER3 signaling pathway|activation of ERBB3 signaling pathway|upregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up-regulation of HER3 signaling pathway|up-regulation of ERBB3 signalling pathway|activation of ERBB3 signalling pathway|activation of HER3 signaling pathway|up regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up-regulation of ERBB3 signaling pathway|positive regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|activation of receptor tyrosine-protein kinase erbB-3 signaling pathway http://purl.obolibrary.org/obo/GO_1905580 GO:2000952 biolink:BiologicalProcess negative regulation of xyloglucan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process. go-plus.json negative regulation of xyloglucan catabolism http://purl.obolibrary.org/obo/GO_2000952 GO:0110064 biolink:BiologicalProcess lncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length. go-plus.json lncRNA catabolism|lncRNA degradation|lncRNA breakdown http://purl.obolibrary.org/obo/GO_0110064 GO:1905581 biolink:BiologicalProcess positive regulation of low-density lipoprotein particle clearance Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance. go-plus.json upregulation of low-density lipoprotein particle clearance|up regulation of LDL clearance|activation of LDL clearance|positive regulation of LDL clearance|up-regulation of low-density lipoprotein particle clearance|activation of low-density lipoprotein particle clearance|up-regulation of LDL clearance|up regulation of low-density lipoprotein particle clearance|upregulation of LDL clearance http://purl.obolibrary.org/obo/GO_1905581 GO:2000953 biolink:BiologicalProcess positive regulation of xyloglucan catabolic process Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process. go-plus.json positive regulation of xyloglucan catabolism http://purl.obolibrary.org/obo/GO_2000953 GO:0110061 biolink:BiologicalProcess regulation of angiotensin-activated signaling pathway Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0110061 GO:0110062 biolink:BiologicalProcess negative regulation of angiotensin-activated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0110062 GO:1905582 biolink:BiologicalProcess response to mannose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905582 GO:2000954 biolink:BiologicalProcess regulation of cyclodextrin metabolic process Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process. go-plus.json regulation of cyclodextrin metabolism http://purl.obolibrary.org/obo/GO_2000954 GO:1905583 biolink:BiologicalProcess cellular response to mannose Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905583 GO:2000955 biolink:BiologicalProcess negative regulation of cyclodextrin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process. go-plus.json negative regulation of cyclodextrin metabolism http://purl.obolibrary.org/obo/GO_2000955 GO:1905584 biolink:BiologicalProcess outer hair cell apoptotic process Any apoptotic process in an outer hair cell. go-plus.json outer hair cell apoptosis|cochlear outer hair cell apoptosis|cochlear outer hair cell apoptotic process http://purl.obolibrary.org/obo/GO_1905584 GO:2000956 biolink:BiologicalProcess positive regulation of cyclodextrin metabolic process Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process. go-plus.json positive regulation of cyclodextrin metabolism http://purl.obolibrary.org/obo/GO_2000956 GO:1905585 biolink:BiologicalProcess regulation of outer hair cell apoptotic process Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process. go-plus.json regulation of cochlear outer hair cell apoptosis|regulation of outer hair cell apoptosis|regulation of cochlear outer hair cell apoptotic process http://purl.obolibrary.org/obo/GO_1905585 GO:2000957 biolink:BiologicalProcess regulation of cyclodextrin catabolic process Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process. go-plus.json regulation of cyclodextrin catabolism http://purl.obolibrary.org/obo/GO_2000957 GO:1905586 biolink:BiologicalProcess negative regulation of outer hair cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process. go-plus.json down regulation of outer hair cell apoptosis|down regulation of cochlear outer hair cell apoptosis|downregulation of outer hair cell apoptosis|downregulation of cochlear outer hair cell apoptotic process|down regulation of outer hair cell apoptotic process|down regulation of cochlear outer hair cell apoptotic process|downregulation of outer hair cell apoptotic process|inhibition of cochlear outer hair cell apoptosis|inhibition of cochlear outer hair cell apoptotic process|down-regulation of outer hair cell apoptosis|negative regulation of outer hair cell apoptosis|down-regulation of outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptosis|down-regulation of cochlear outer hair cell apoptosis|inhibition of outer hair cell apoptotic process|inhibition of outer hair cell apoptosis|down-regulation of cochlear outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptotic process|downregulation of cochlear outer hair cell apoptosis http://purl.obolibrary.org/obo/GO_1905586 GO:2000958 biolink:BiologicalProcess negative regulation of cyclodextrin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process. go-plus.json negative regulation of cyclodextrin catabolism http://purl.obolibrary.org/obo/GO_2000958 GO:1905576 biolink:MolecularActivity ganglioside GT1b binding Binding to ganglioside GT1b. go-plus.json http://purl.obolibrary.org/obo/GO_1905576 GO:1905577 biolink:MolecularActivity ganglioside GP1c binding Binding to ganglioside GP1c. go-plus.json http://purl.obolibrary.org/obo/GO_1905577 GO:1905578 biolink:BiologicalProcess regulation of ERBB3 signaling pathway Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway. go-plus.json regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|regulation of HER3 signaling pathway|regulation of ERBB3 signalling pathway http://purl.obolibrary.org/obo/GO_1905578 CHEBI:16768 biolink:ChemicalSubstance mycothiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16768 chebi_ph7_3 GO:1905579 biolink:BiologicalProcess negative regulation of ERBB3 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway. go-plus.json down regulation of ERBB3 signalling pathway|down regulation of HER3 signaling pathway|inhibition of ERBB3 signalling pathway|inhibition of HER3 signaling pathway|down-regulation of ERBB3 signaling pathway|down regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|downregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|inhibition of ERBB3 signaling pathway|negative regulation of ERBB3 signalling pathway|down-regulation of ERBB3 signalling pathway|down-regulation of HER3 signaling pathway|negative regulation of HER3 signaling pathway|down-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|negative regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|down regulation of ERBB3 signaling pathway|inhibition of receptor tyrosine-protein kinase erbB-3 signaling pathway|downregulation of ERBB3 signalling pathway|downregulation of HER3 signaling pathway|downregulation of ERBB3 signaling pathway http://purl.obolibrary.org/obo/GO_1905579 CHEBI:16769 biolink:ChemicalSubstance 2-oxoglutaramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16769 chebi_ph7_3 CHEBI:16766 biolink:ChemicalSubstance 4-carboxymethyl-4-methylbut-2-en-1,4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16766 CHEBI:16767 biolink:ChemicalSubstance 3,4-dichloroaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16767 chebi_ph7_3 CHEBI:16764 biolink:ChemicalSubstance 2'-deoxy-5-methyl-5'-cytidylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16764 GO:2000950 biolink:BiologicalProcess positive regulation of xyloglucan metabolic process Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process. go-plus.json positive regulation of xyloglucan metabolism http://purl.obolibrary.org/obo/GO_2000950 CHEBI:16765 biolink:ChemicalSubstance tryptamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16765 GO:0051162 biolink:BiologicalProcess L-arabitol metabolic process The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. go-plus.json L-arabitol metabolism http://purl.obolibrary.org/obo/GO_0051162 CHEBI:16763 biolink:ChemicalSubstance 2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16763 chebi_ph7_3 GO:0051163 biolink:BiologicalProcess D-arabitol metabolic process The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. go-plus.json D-arabitol metabolism http://purl.obolibrary.org/obo/GO_0051163 GO:0051160 biolink:BiologicalProcess L-xylitol catabolic process The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. go-plus.json L-xylitol degradation|L-xylitol breakdown|L-xylitol catabolism http://purl.obolibrary.org/obo/GO_0051160 CHEBI:16760 biolink:ChemicalSubstance phenanthrene-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16760 chebi_ph7_3 GO:0075110 biolink:BiologicalProcess induction by symbiont of host receptor-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host receptor-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075110 GO:0051161 biolink:BiologicalProcess arabitol metabolic process The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. go-plus.json arabitol metabolism http://purl.obolibrary.org/obo/GO_0051161 CHEBI:16761 biolink:ChemicalSubstance ADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16761 GO:0075111 biolink:BiologicalProcess suppression by symbiont of host receptor-mediated signal transduction Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host receptor-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075111 GO:0051166 biolink:BiologicalProcess 2,5-dihydroxypyridine catabolic process The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine. go-plus.json 2,5-dihydroxypyridine degradation|pyridine-2,5-diol catabolic process|2,5-dihydroxypyridine catabolism|2,5-dihydroxypyridine breakdown http://purl.obolibrary.org/obo/GO_0051166 GO:0099108 biolink:MolecularActivity potassium channel activator activity involved in G protein-coupled receptor signaling pathway Activation potassium ion channel activity via direct interaction with a potassium ion channel during G protein-coupled receptor signaling. go-plus.json potassium channel activator activity involved in G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0099108 goslim_synapse GO:0075112 biolink:BiologicalProcess modulation by symbiont of host transmembrane receptor-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075112 GO:0051167 biolink:BiologicalProcess xylulose 5-phosphate metabolic process The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway. go-plus.json D-xylulose 5-phosphate metabolism|xylulose-5-phosphate metabolic process|D-xylulose 5-phosphate metabolic process|xylulose-5-phosphate metabolism|D-xylulose-5-phosphate metabolism|xylulose 5-phosphate metabolism|D-xylulose-5-phosphate metabolic process http://purl.obolibrary.org/obo/GO_0051167 GO:0099109 biolink:BiologicalProcess potassium channel activating, G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel. go-plus.json potassium channel activating, G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0099109 GO:0075113 biolink:BiologicalProcess induction by symbiont of host transmembrane receptor-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host transmembrane receptor-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075113 GO:0051164 biolink:BiologicalProcess L-xylitol metabolic process The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets. go-plus.json L-xylitol metabolism http://purl.obolibrary.org/obo/GO_0051164 GO:0099106 biolink:MolecularActivity ion channel regulator activity Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. go-plus.json http://purl.obolibrary.org/obo/GO_0099106 GO:0075114 biolink:BiologicalProcess suppression by symbiont of host transmembrane receptor-mediated signal transduction Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host transmembrane receptor-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075114 GO:0099107 biolink:MolecularActivity ion channel regulator activity involved in G protein-coupled receptor signaling pathway Modulation of the activity of an ion channel via direct interaction with it as part of G protein-coupled receptor signaling. go-plus.json ion channel regulator activity involved in G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0099107 GO:0051165 biolink:BiologicalProcess 2,5-dihydroxypyridine metabolic process The chemical reactions and pathways involving 2,5-dihydroxypyridine. go-plus.json 2,5-dihydroxypyridine metabolism|pyridine-2,5-diol metabolic process http://purl.obolibrary.org/obo/GO_0051165 GO:0075148 biolink:BiologicalProcess obsolete positive regulation of signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075148 GO:0075149 biolink:BiologicalProcess obsolete negative regulation of signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075149 GO:0051179 biolink:BiologicalProcess localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. go-plus.json establishment and maintenance of cellular component location|establishment and maintenance of substrate location|establishment and maintenance of localization|single-organism localization|localisation|single organism localization|establishment and maintenance of substance location|establishment and maintenance of position http://purl.obolibrary.org/obo/GO_0051179 goslim_pir GO:0110078 biolink:CellularComponent TTT complex A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209). go-plus.json Triple T complex|TELO2-TTI1-TTI2|Tel2-Tti1-Tti2 http://purl.obolibrary.org/obo/GO_0110078 GO:0110079 biolink:BiologicalProcess regulation of placenta blood vessel development Any process that modulates the frequency, rate or extent of placenta blood vessel development. go-plus.json http://purl.obolibrary.org/obo/GO_0110079 GO:0110076 biolink:BiologicalProcess negative regulation of ferroptosis Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis. go-plus.json http://purl.obolibrary.org/obo/GO_0110076 NCBITaxon:4432 biolink:OrganismalEntity Nelumbo nucifera go-plus.json sacred lotus|padma|Indian lotus http://purl.obolibrary.org/obo/NCBITaxon_4432 GO:0110077 biolink:BiologicalProcess vesicle-mediated intercellular transport A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0110077 GO:0110074 biolink:BiologicalProcess positive regulation of apical constriction involved in ventral furrow formation Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation. go-plus.json http://purl.obolibrary.org/obo/GO_0110074 GO:2000962 biolink:BiologicalProcess positive regulation of cellooligosaccharide metabolic process Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process. go-plus.json positive regulation of cellooligosaccharide metabolism http://purl.obolibrary.org/obo/GO_2000962 GO:1905590 biolink:BiologicalProcess fibronectin fibril organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril. go-plus.json http://purl.obolibrary.org/obo/GO_1905590 GO:0110075 biolink:BiologicalProcess regulation of ferroptosis Any process that modulates the frequency, rate or extent of ferroptosis. go-plus.json http://purl.obolibrary.org/obo/GO_0110075 GO:1905591 biolink:BiologicalProcess regulation of optical nerve axon regeneration Any process that modulates the frequency, rate or extent of optical nerve axon regeneration. go-plus.json http://purl.obolibrary.org/obo/GO_1905591 GO:2000963 biolink:BiologicalProcess regulation of cellooligosaccharide catabolic process Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process. go-plus.json regulation of cellooligosaccharide catabolism http://purl.obolibrary.org/obo/GO_2000963 GO:1905592 biolink:BiologicalProcess negative regulation of optical nerve axon regeneration Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration. go-plus.json down regulation of optical nerve axon regeneration|downregulation of optical nerve axon regeneration|down-regulation of optical nerve axon regeneration|inhibition of optical nerve axon regeneration http://purl.obolibrary.org/obo/GO_1905592 GO:0110072 biolink:BiologicalProcess apical constriction involved in ventral furrow formation The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0110072 GO:2000964 biolink:BiologicalProcess negative regulation of cellooligosaccharide catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process. go-plus.json negative regulation of cellooligosaccharide catabolism http://purl.obolibrary.org/obo/GO_2000964 GO:0110073 biolink:BiologicalProcess regulation of apical constriction involved in ventral furrow formation Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation. go-plus.json http://purl.obolibrary.org/obo/GO_0110073 GO:1905593 biolink:BiologicalProcess positive regulation of optical nerve axon regeneration Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration. go-plus.json upregulation of optical nerve axon regeneration|up regulation of optical nerve axon regeneration|activation of optical nerve axon regeneration|up-regulation of optical nerve axon regeneration http://purl.obolibrary.org/obo/GO_1905593 GO:2000965 biolink:BiologicalProcess positive regulation of cellooligosaccharide catabolic process Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process. go-plus.json positive regulation of cellooligosaccharide catabolism http://purl.obolibrary.org/obo/GO_2000965 GO:1905594 biolink:MolecularActivity resveratrol binding Binding to resveratrol. go-plus.json http://purl.obolibrary.org/obo/GO_1905594 GO:0110070 biolink:CellularComponent cellularization cleavage furrow A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0110070 GO:2000966 biolink:BiologicalProcess regulation of cell wall polysaccharide catabolic process Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process. go-plus.json regulation of cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_2000966 GO:1905595 biolink:BiologicalProcess regulation of low-density lipoprotein particle receptor binding Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding. go-plus.json regulation of LDL receptor binding|regulation of low-density lipoprotein receptor binding http://purl.obolibrary.org/obo/GO_1905595 GO:2000967 biolink:BiologicalProcess negative regulation of cell wall polysaccharide catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process. go-plus.json negative regulation of cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_2000967 GO:0110071 biolink:CellularComponent cellularization cleavage furrow invagination front The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0110071 GO:1905596 biolink:BiologicalProcess negative regulation of low-density lipoprotein particle receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding. go-plus.json inhibition of low-density lipoprotein particle receptor binding|down-regulation of LDL receptor binding|negative regulation of LDL receptor binding|negative regulation of low-density lipoprotein receptor binding|down-regulation of low-density lipoprotein receptor binding|downregulation of LDL receptor binding|down regulation of low-density lipoprotein particle receptor binding|downregulation of low-density lipoprotein receptor binding|down regulation of LDL receptor binding|inhibition of LDL receptor binding|down regulation of low-density lipoprotein receptor binding|downregulation of low-density lipoprotein particle receptor binding|inhibition of low-density lipoprotein receptor binding|down-regulation of low-density lipoprotein particle receptor binding http://purl.obolibrary.org/obo/GO_1905596 GO:2000968 biolink:BiologicalProcess positive regulation of cell wall polysaccharide catabolic process Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process. go-plus.json positive regulation of cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_2000968 GO:1905597 biolink:BiologicalProcess positive regulation of low-density lipoprotein particle receptor binding Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding. go-plus.json activation of low-density lipoprotein receptor binding|up-regulation of low-density lipoprotein receptor binding|up-regulation of low-density lipoprotein particle receptor binding|positive regulation of LDL receptor binding|up regulation of LDL receptor binding|positive regulation of low-density lipoprotein receptor binding|up regulation of low-density lipoprotein receptor binding|upregulation of low-density lipoprotein particle receptor binding|upregulation of LDL receptor binding|upregulation of low-density lipoprotein receptor binding|up regulation of low-density lipoprotein particle receptor binding|activation of low-density lipoprotein particle receptor binding|activation of LDL receptor binding|up-regulation of LDL receptor binding http://purl.obolibrary.org/obo/GO_1905597 GO:2000969 biolink:BiologicalProcess positive regulation of AMPA receptor activity Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity. go-plus.json positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity http://purl.obolibrary.org/obo/GO_2000969 GO:1905587 biolink:BiologicalProcess positive regulation of outer hair cell apoptotic process Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process. go-plus.json positive regulation of cochlear outer hair cell apoptotic process|up regulation of cochlear outer hair cell apoptotic process|upregulation of outer hair cell apoptotic process|upregulation of cochlear outer hair cell apoptosis|up regulation of outer hair cell apoptosis|positive regulation of outer hair cell apoptosis|upregulation of cochlear outer hair cell apoptotic process|up regulation of outer hair cell apoptotic process|activation of outer hair cell apoptotic process|activation of outer hair cell apoptosis|up-regulation of cochlear outer hair cell apoptosis|up-regulation of outer hair cell apoptosis|activation of cochlear outer hair cell apoptosis|up-regulation of cochlear outer hair cell apoptotic process|activation of cochlear outer hair cell apoptotic process|up-regulation of outer hair cell apoptotic process|positive regulation of cochlear outer hair cell apoptosis|up regulation of cochlear outer hair cell apoptosis|upregulation of outer hair cell apoptosis http://purl.obolibrary.org/obo/GO_1905587 GO:1905588 biolink:BiologicalProcess plant-type cell wall modification involved in stomatal movement Any plant-type cell wall modification that is involved in stomatal movement. go-plus.json cellulose and pectin-containing cell wall modification involved in stomatal movement http://purl.obolibrary.org/obo/GO_1905588 GO:1905589 biolink:BiologicalProcess positive regulation of L-arginine import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane. go-plus.json positive regulation of L-arginine uptake|activation of L-arginine uptake|up-regulation of L-arginine import into cell|up-regulation of L-arginine import|up-regulation of L-arginine uptake|positive regulation of L-arginine import into cell|activation of L-arginine import across plasma membrane|upregulation of L-arginine import into cell|upregulation of L-arginine import|upregulation of L-arginine uptake|positive regulation of L-arginine import|up regulation of L-arginine import|activation of L-arginine import into cell|activation of L-arginine import|up regulation of L-arginine uptake http://purl.obolibrary.org/obo/GO_1905589 CHEBI:16799 biolink:ChemicalSubstance 16alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16799 chebi_ph7_3 GO:0051170 biolink:BiologicalProcess import into nucleus The directed movement of substances into the nucleus. go-plus.json single organism nuclear import|single-organism nuclear import|nuclear import|substance nuclear import http://purl.obolibrary.org/obo/GO_0051170 GO:2000960 biolink:BiologicalProcess regulation of cellooligosaccharide metabolic process Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process. go-plus.json regulation of cellooligosaccharide metabolism http://purl.obolibrary.org/obo/GO_2000960 CHEBI:16797 biolink:ChemicalSubstance 1-methylnicotinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16797 chebi_ph7_3 GO:2000961 biolink:BiologicalProcess negative regulation of cellooligosaccharide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process. go-plus.json negative regulation of cellooligosaccharide metabolism http://purl.obolibrary.org/obo/GO_2000961 CHEBI:41721 biolink:ChemicalSubstance L-cysteine-S-dioxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_41721 GO:0051173 biolink:BiologicalProcess positive regulation of nitrogen compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. go-plus.json upregulation of nitrogen metabolic process|stimulation of nitrogen metabolic process|up-regulation of nitrogen metabolic process|activation of nitrogen metabolic process|positive regulation of nitrogen metabolic process|up regulation of nitrogen metabolic process|positive regulation of nitrogen metabolism http://purl.obolibrary.org/obo/GO_0051173 CHEBI:16795 biolink:ChemicalSubstance L-threo-3-phenylserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16795 GO:0075140 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075140 GO:0075141 biolink:BiologicalProcess obsolete symbiont tolerance to host environment OBSOLETE. Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against the components of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json maintenance of symbiont tolerance to host pH environment|maintenance of symbiont tolerance to host redox environment|maintenance of symbiont tolerance to host oxygen tension environment|maintenance of symbiont tolerance to host environment|maintenance of symbiont tolerance to host iron concentration|maintenance of symbiont tolerance to host osmotic environment http://purl.obolibrary.org/obo/GO_0075141 GO:0051174 biolink:BiologicalProcess regulation of phosphorus metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. go-plus.json regulation of phosphorus metabolism http://purl.obolibrary.org/obo/GO_0051174 CHEBI:16796 biolink:ChemicalSubstance melatonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16796 chebi_ph7_3 GO:0075142 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075142 GO:0051171 biolink:BiologicalProcess regulation of nitrogen compound metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. go-plus.json regulation of nitrogen metabolism|regulation of nitrogen metabolic process http://purl.obolibrary.org/obo/GO_0051171 CHEBI:16793 biolink:ChemicalSubstance mercury(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16793 chebi_ph7_3 GO:0051172 biolink:BiologicalProcess negative regulation of nitrogen compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. go-plus.json negative regulation of nitrogen metabolic process|down-regulation of nitrogen metabolic process|downregulation of nitrogen metabolic process|negative regulation of nitrogen metabolism|down regulation of nitrogen metabolic process|inhibition of nitrogen metabolic process http://purl.obolibrary.org/obo/GO_0051172 GO:0075143 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075143 CHEBI:16794 biolink:ChemicalSubstance scopolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16794 chebi_ph7_3 GO:0051177 biolink:BiologicalProcess meiotic sister chromatid cohesion The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0051177 GO:0075144 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075144 GO:0090741 biolink:CellularComponent pigment granule membrane Any membrane that is part of a pigment granule. go-plus.json http://purl.obolibrary.org/obo/GO_0090741 CHEBI:16791 biolink:ChemicalSubstance vinorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16791 chebi_ph7_3 GO:0051178 biolink:BiologicalProcess meiotic chromosome decondensation The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells. go-plus.json http://purl.obolibrary.org/obo/GO_0051178 GO:0075145 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075145 CHEBI:16792 biolink:ChemicalSubstance oxidized Photinus luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16792 chebi_ph7_3 GO:0051175 biolink:BiologicalProcess negative regulation of sulfur metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. go-plus.json inhibition of sulfur metabolic process|negative regulation of sulphur metabolism|negative regulation of sulphur metabolic process|down-regulation of sulfur metabolic process|negative regulation of sulfur metabolism|downregulation of sulfur metabolic process|down regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0051175 GO:0075146 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075146 UBERON:0008367 biolink:AnatomicalEntity breast epithelium An epithelium that is part of a breast. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008367 GO:0051176 biolink:BiologicalProcess positive regulation of sulfur metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. go-plus.json upregulation of sulfur metabolic process|positive regulation of sulphur metabolic process|positive regulation of sulphur metabolism|stimulation of sulfur metabolic process|up-regulation of sulfur metabolic process|activation of sulfur metabolic process|positive regulation of sulfur metabolism|up regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0051176 GO:0075147 biolink:BiologicalProcess obsolete regulation of signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of symbiont signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075147 GO:0090740 biolink:CellularComponent integral component of pigment granule membrane The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090740 NCBITaxon:1286322 biolink:OrganismalEntity Leishmaniinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1286322 CHEBI:16790 biolink:ChemicalSubstance 15,16-dihydrobiliverdin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16790 GO:0075137 biolink:BiologicalProcess response to host redox environment Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response of symbiont to host redox environment http://purl.obolibrary.org/obo/GO_0075137 GO:0075138 biolink:BiologicalProcess response to host oxygen tension environment Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response of symbiont to host oxygen tension environment http://purl.obolibrary.org/obo/GO_0075138 GO:0075139 biolink:BiologicalProcess response to host iron concentration Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response of symbiont to host iron concentration http://purl.obolibrary.org/obo/GO_0075139 NCBITaxon:4447 biolink:OrganismalEntity Liliopsida go-plus.json monocotyledons|Monocotyledoneae|monocots|monocots http://purl.obolibrary.org/obo/NCBITaxon_4447 GO:0110089 biolink:BiologicalProcess regulation of hippocampal neuron apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0110089 GO:0110087 biolink:BiologicalProcess suppression by virus of host protease activator activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity. go-plus.json http://purl.obolibrary.org/obo/GO_0110087 GO:0110088 biolink:BiologicalProcess hippocampal neuron apoptotic process Any apoptotic process that occurs in a hippocampal neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0110088 GO:2000973 biolink:BiologicalProcess regulation of pro-B cell differentiation Any process that modulates the frequency, rate or extent of pro-B cell differentiation. go-plus.json regulation of pro-B lymphocyte differentiation|regulation of pro-B cell development http://purl.obolibrary.org/obo/GO_2000973 GO:0110085 biolink:CellularComponent mitotic actomyosin contractile ring A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0110085 GO:0110086 biolink:CellularComponent meiotic actomyosin contractile ring A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110086 GO:2000974 biolink:BiologicalProcess negative regulation of pro-B cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation. go-plus.json negative regulation of pro-B cell development|negative regulation of pro-B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000974 GO:0110083 biolink:BiologicalProcess positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0110083 GO:2000975 biolink:BiologicalProcess positive regulation of pro-B cell differentiation Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation. go-plus.json positive regulation of pro-B cell development|positive regulation of pro-B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_2000975 GO:2000976 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in detection of glucose OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in detection of glucose. go-plus.json regulation of transcription from RNA polymerase II promoter, global involved in glucose perception|regulation of global transcription from Pol II promoter involved in glucose sensing|regulation of global transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose perception|regulation of global transcription from Pol II promoter involved in glucose detection|regulation of gene-specific transcription from RNA polymerase II promoter involved in detection of glucose|regulation of transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in glucose detection|global transcription regulation from Pol II promoter involved in detection of glucose|global transcription regulation from Pol II promoter involved in glucose sensing|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose sensing|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose perception|global transcription regulation from Pol II promoter involved in glucose detection|global transcription regulation from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in detection of glucose|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose detection|regulation of global transcription from Pol II promoter involved in detection of glucose|regulation of transcription from Pol II promoter involved in glucose sensing|regulation of transcription from Pol II promoter involved in glucose detection|regulation of transcription from RNA polymerase II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose detection|regulation of transcription from Pol II promoter involved in detection of glucose http://purl.obolibrary.org/obo/GO_2000976 GO:0110084 biolink:BiologicalProcess negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0110084 GO:0110081 biolink:BiologicalProcess negative regulation of placenta blood vessel development Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development. go-plus.json http://purl.obolibrary.org/obo/GO_0110081 GO:2000977 biolink:BiologicalProcess regulation of forebrain neuron differentiation Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000977 GO:2000978 biolink:BiologicalProcess negative regulation of forebrain neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000978 GO:0110082 biolink:BiologicalProcess regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0110082 GO:2000979 biolink:BiologicalProcess positive regulation of forebrain neuron differentiation Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000979 GO:0110080 biolink:BiologicalProcess positive regulation of placenta blood vessel development Any process that activates or increases the frequency, rate or extent of placenta blood vessel development. go-plus.json http://purl.obolibrary.org/obo/GO_0110080 GO:1905598 biolink:BiologicalProcess negative regulation of low-density lipoprotein receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity. go-plus.json inhibition of LDLR activity|down-regulation of low-density lipoprotein receptor activity|down-regulation of LDL receptor|negative regulation of LDL receptor|inhibition of low-density lipoprotein receptor activity|down regulation of LDLR activity|downregulation of LDL receptor|downregulation of LDLR activity|down regulation of LDL receptor|down regulation of low-density lipoprotein receptor activity|inhibition of LDL receptor|downregulation of low-density lipoprotein receptor activity|negative regulation of LDLR activity|down-regulation of LDLR activity http://purl.obolibrary.org/obo/GO_1905598 GO:1905599 biolink:BiologicalProcess positive regulation of low-density lipoprotein receptor activity Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity. go-plus.json up regulation of low-density lipoprotein receptor activity|activation of low-density lipoprotein receptor activity|up-regulation of LDL receptor|activation of LDL receptor|up-regulation of LDLR activity|up-regulation of low-density lipoprotein receptor activity|upregulation of LDLR activity|positive regulation of LDL receptor|up regulation of LDL receptor|upregulation of low-density lipoprotein receptor activity|up regulation of LDLR activity|activation of LDLR activity|positive regulation of LDLR activity|upregulation of LDL receptor http://purl.obolibrary.org/obo/GO_1905599 GO:0051180 biolink:BiologicalProcess vitamin transport The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json vitamin or cofactor transport http://purl.obolibrary.org/obo/GO_0051180 goslim_pir CHEBI:16788 biolink:ChemicalSubstance CMP-N-acyl-beta-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16788 GO:0051181 biolink:BiologicalProcess obsolete cofactor transport OBSOLETE. The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein. go-plus.json vitamin or cofactor transport http://purl.obolibrary.org/obo/GO_0051181 CHEBI:16789 biolink:ChemicalSubstance aldehydo-D-lyxose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16789 chebi_ph7_3 GO:2000970 biolink:BiologicalProcess regulation of detection of glucose Any process that modulates the frequency, rate or extent of detection of glucose. go-plus.json regulation of glucose perception|regulation of glucose sensing|regulation of glucose detection http://purl.obolibrary.org/obo/GO_2000970 GO:2000971 biolink:BiologicalProcess negative regulation of detection of glucose Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose. go-plus.json negative regulation of glucose perception|negative regulation of glucose sensing|negative regulation of glucose detection http://purl.obolibrary.org/obo/GO_2000971 CHEBI:16786 biolink:ChemicalSubstance vestitone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16786 chebi_ph7_3 GO:2000972 biolink:BiologicalProcess positive regulation of detection of glucose Any process that activates or increases the frequency, rate or extent of detection of glucose. go-plus.json positive regulation of glucose perception|positive regulation of glucose sensing|positive regulation of glucose detection http://purl.obolibrary.org/obo/GO_2000972 CHEBI:16787 biolink:ChemicalSubstance 1-phospho-alpha-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16787 CHEBI:41710 biolink:ChemicalSubstance S-hydroxy-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_41710 GO:0051184 biolink:MolecularActivity obsolete cofactor transmembrane transporter activity OBSOLETE. Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein. go-plus.json cofactor transporter activity|vitamin or cofactor transporter activity http://purl.obolibrary.org/obo/GO_0051184 CHEBI:16784 biolink:ChemicalSubstance 6beta-hydroxy-17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16784 chebi_ph7_3 GO:0075130 biolink:BiologicalProcess modulation by symbiont of host protein kinase-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075130 GO:0051185 biolink:MolecularActivity obsolete coenzyme transmembrane transporter activity OBSOLETE. Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. go-plus.json coenzyme transporter activity http://purl.obolibrary.org/obo/GO_0051185 CHEBI:16785 biolink:ChemicalSubstance diisopropyl hydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16785 GO:0051182 biolink:BiologicalProcess obsolete coenzyme transport OBSOLETE. The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. go-plus.json http://purl.obolibrary.org/obo/GO_0051182 GO:0075131 biolink:BiologicalProcess induction by symbiont of host protein kinase-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host protein kinase-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075131 CHEBI:16782 biolink:ChemicalSubstance (S)-2-hydroxyglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16782 chebi_ph7_3 GO:0075132 biolink:BiologicalProcess suppression by symbiont of host protein kinase-mediated signal transduction Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host protein kinase-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075132 GO:0051183 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051183 CHEBI:16783 biolink:ChemicalSubstance 1D-myo-inositol 1,3,4,5-tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16783 CHEBI:16780 biolink:ChemicalSubstance N-(6-aminohexanoyl)-6-aminohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16780 GO:0051188 biolink:BiologicalProcess obsolete cofactor biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein. go-plus.json cofactor anabolism|cofactor biosynthesis|cofactor synthesis|cofactor formation http://purl.obolibrary.org/obo/GO_0051188 GO:0075133 biolink:BiologicalProcess modulation by symbiont of host calcium or calmodulin-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host Ca++ or calmodulin-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075133 GO:0051189 biolink:BiologicalProcess prosthetic group metabolic process The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. go-plus.json coenzyme and prosthetic group metabolic process|prosthetic group metabolism|coenzyme and prosthetic group metabolism http://purl.obolibrary.org/obo/GO_0051189 goslim_pir GO:0075134 biolink:BiologicalProcess induction by symbiont of host calcium or calmodulin-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host calcium or calmodulin-mediated signal transduction|positive regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075134 GO:0051186 biolink:BiologicalProcess obsolete cofactor metabolic process OBSOLETE. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. go-plus.json cofactor metabolism http://purl.obolibrary.org/obo/GO_0051186 GO:0075135 biolink:BiologicalProcess suppression by symbiont of host calcium or calmodulin-mediated signal transduction Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host calcium or calmodulin-mediated signal transduction|negative regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075135 GO:0051187 biolink:BiologicalProcess obsolete cofactor catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein. go-plus.json cofactor catabolism|cofactor degradation|cofactor breakdown http://purl.obolibrary.org/obo/GO_0051187 GO:0075136 biolink:BiologicalProcess response to host Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response of symbiont to host http://purl.obolibrary.org/obo/GO_0075136 GO:0002104 biolink:BiologicalProcess endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0002104 GO:0002105 biolink:BiologicalProcess endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0002105 GO:0002106 biolink:BiologicalProcess endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0002106 GO:0002107 biolink:BiologicalProcess generation of mature 3'-end of 5S rRNA generated by RNA polymerase III The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end. go-plus.json http://purl.obolibrary.org/obo/GO_0002107 GO:0002100 biolink:BiologicalProcess tRNA wobble adenosine to inosine editing The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine. go-plus.json http://purl.obolibrary.org/obo/GO_0002100 GO:0002101 biolink:BiologicalProcess tRNA wobble cytosine modification The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified. go-plus.json http://purl.obolibrary.org/obo/GO_0002101 GO:0002102 biolink:CellularComponent podosome An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. Wikipedia:Podosome go-plus.json http://purl.obolibrary.org/obo/GO_0002102 GO:0002103 biolink:BiologicalProcess endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0002103 GO:0016749 biolink:MolecularActivity N-succinyltransferase activity Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016749 GO:0016745 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016745 GO:0016746 biolink:MolecularActivity acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). Reactome:R-HSA-6792572|Reactome:R-HSA-193491|Reactome:R-HSA-192312|Reactome:R-HSA-159431|Reactome:R-HSA-8858298|EC:2.3.-.- go-plus.json transferase activity, transferring acyl groups|acyltransferase activity http://purl.obolibrary.org/obo/GO_0016746 goslim_chembl|goslim_drosophila|goslim_generic GO:0016747 biolink:MolecularActivity acyltransferase activity, transferring groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). EC:2.3.1.- go-plus.json transferase activity, transferring groups other than amino-acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups http://purl.obolibrary.org/obo/GO_0016747 CHEBI:51060 biolink:ChemicalSubstance hormone agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_51060 GO:0016748 biolink:MolecularActivity succinyltransferase activity Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016748 CHEBI:51061 biolink:ChemicalSubstance hormone receptor modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_51061 GO:0016741 biolink:MolecularActivity transferase activity, transferring one-carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). EC:2.1.-.- go-plus.json methyltransferase activity http://purl.obolibrary.org/obo/GO_0016741 GO:0016742 biolink:MolecularActivity hydroxymethyl-, formyl- and related transferase activity Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor). EC:2.1.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016742 GO:0016743 biolink:MolecularActivity carboxyl- or carbamoyltransferase activity Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor). EC:2.1.3.- go-plus.json carboxyl- and carbamoyltransferase activity http://purl.obolibrary.org/obo/GO_0016743 GO:0016744 biolink:MolecularActivity transketolase or transaldolase activity Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor). EC:2.2.1.- go-plus.json transferase activity, transferring aldehyde or ketonic groups http://purl.obolibrary.org/obo/GO_0016744 CHEBI:90675 biolink:ChemicalSubstance ribonucleotide residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90675 chebi_ph7_3 CHEBI:75034 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75034 chebi_ph7_3 CHEBI:90676 biolink:ChemicalSubstance 2'-O-methylribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90676 chebi_ph7_3 CHEBI:75031 biolink:ChemicalSubstance 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75031 chebi_ph7_3 GO:0016740 biolink:MolecularActivity transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. Reactome:R-HSA-8868783|EC:2.-.-.-|Reactome:R-HSA-1483089|Reactome:R-HSA-1483186|Reactome:R-HSA-5668414 go-plus.json http://purl.obolibrary.org/obo/GO_0016740 goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics CHEBI:75032 biolink:ChemicalSubstance 1-palmitoyl-2-arachidonoyl-sn-glycero3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75032 chebi_ph7_3 CHEBI:51069 biolink:ChemicalSubstance organic halide salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_51069 GO:0002108 biolink:BiologicalProcess maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0002108 GO:0002109 biolink:BiologicalProcess maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0002109 CHEBI:75038 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75038 chebi_ph7_3 CHEBI:75036 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75036 chebi_ph7_3 GO:0002115 biolink:BiologicalProcess store-operated calcium entry A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum. go-plus.json store-operated calcium import|calcium ion import|capacitative calcium entry|SOCE http://purl.obolibrary.org/obo/GO_0002115 GO:0002116 biolink:CellularComponent semaphorin receptor complex A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor. go-plus.json plexin-neurophilin complex http://purl.obolibrary.org/obo/GO_0002116 GO:0002117 biolink:BiologicalProcess amphibian larval development The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form. go-plus.json http://purl.obolibrary.org/obo/GO_0002117 GO:0002118 biolink:BiologicalProcess aggressive behavior A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual. Wikipedia:Aggression go-plus.json aggression http://purl.obolibrary.org/obo/GO_0002118 GO:0002111 biolink:CellularComponent BRCA2-BRAF35 complex A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0002111 GO:0002112 biolink:MolecularActivity interleukin-33 receptor binding Binding to an interleukin-33 receptor. go-plus.json interleukin-33 receptor ligand|IL-33 http://purl.obolibrary.org/obo/GO_0002112 GO:0002113 biolink:MolecularActivity interleukin-33 binding Binding to interleukin-33. go-plus.json IL-33 binding http://purl.obolibrary.org/obo/GO_0002113 GO:0002114 biolink:MolecularActivity interleukin-33 receptor activity Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-33R|IL-33 receptor activity http://purl.obolibrary.org/obo/GO_0002114 GO:0002110 biolink:BiologicalProcess cotranscriptional mitochondrial rRNA nucleotide insertion The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis. go-plus.json http://purl.obolibrary.org/obo/GO_0002110 GO:0016756 biolink:MolecularActivity glutathione gamma-glutamylcysteinyltransferase activity Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly. MetaCyc:2.3.2.15-RXN|EC:2.3.2.15|RHEA:17917 go-plus.json gamma-glutamylcysteine dipeptidyl transpeptidase activity|glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity|phytochelatin synthase activity http://purl.obolibrary.org/obo/GO_0016756 GO:0016757 biolink:MolecularActivity glycosyltransferase activity Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). Reactome:R-HSA-5173005|Reactome:R-HSA-6785565|EC:2.4.-.- go-plus.json transferase activity, transferring glycosyl groups|transferase activity, transferring other glycosyl groups|transglycosidase activity|transglycosylase activity http://purl.obolibrary.org/obo/GO_0016757 goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast GO:0016758 biolink:MolecularActivity hexosyltransferase activity Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). EC:2.4.1.- go-plus.json transferase activity, transferring hexosyl groups http://purl.obolibrary.org/obo/GO_0016758 GO:0016759 biolink:MolecularActivity cellulose synthase activity Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1). go-plus.json cellulose synthetase activity http://purl.obolibrary.org/obo/GO_0016759 GO:0016752 biolink:MolecularActivity sinapoyltransferase activity Catalysis of the transfer of a sinapoyl group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016752 GO:0016753 biolink:MolecularActivity O-sinapoyltransferase activity Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016753 GO:0016754 biolink:MolecularActivity sinapoylglucose-malate O-sinapoyltransferase activity Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate. MetaCyc:2.3.1.92-RXN|RHEA:12625|KEGG_REACTION:R03323|EC:2.3.1.92 go-plus.json sinapoylglucose:malate sinapoyltransferase activity|1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity|1-sinapoylglucose-L-malate sinapoyltransferase activity http://purl.obolibrary.org/obo/GO_0016754 GO:0016755 biolink:MolecularActivity aminoacyltransferase activity Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). EC:2.3.2.- go-plus.json transferase activity, transferring amino-acyl groups|aminoacyltransferase activity http://purl.obolibrary.org/obo/GO_0016755 GO:0016750 biolink:MolecularActivity O-succinyltransferase activity Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016750 CHEBI:51057 biolink:ChemicalSubstance 3-phenylpropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51057 chebi_ph7_3 GO:0016751 biolink:MolecularActivity S-succinyltransferase activity Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016751 GO:0002119 biolink:BiologicalProcess nematode larval development The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go-plus.json http://purl.obolibrary.org/obo/GO_0002119 CHEBI:51051 biolink:ChemicalSubstance N-(3-acetamidopropyl)-4-aminobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_51051 NCBITaxon:4479 biolink:OrganismalEntity Poaceae go-plus.json grass family|Gramineae|Bambusaceae http://purl.obolibrary.org/obo/NCBITaxon_4479 GO:0016727 biolink:MolecularActivity oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule. EC:1.17.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016727 GO:0016728 biolink:MolecularActivity oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group. EC:1.17.4.- go-plus.json oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016728 GO:0016729 biolink:MolecularActivity obsolete oxidoreductase activity, acting on CH2 groups, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen. go-plus.json oxidoreductase activity, acting on CH2 groups, other acceptors http://purl.obolibrary.org/obo/GO_0016729 CHEBI:26087 biolink:ChemicalSubstance photosynthetic electron-transport chain inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_26087 GO:0016723 biolink:MolecularActivity oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor. Reactome:R-HSA-917811|EC:1.16.1.- go-plus.json oxidoreductase activity, reducing metal ions, NAD or NADP as acceptor|oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor http://purl.obolibrary.org/obo/GO_0016723 GO:0016724 biolink:MolecularActivity oxidoreductase activity, acting on metal ions, oxygen as acceptor Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor. EC:1.16.3.- go-plus.json oxidoreductase activity, oxidizing metal ions, oxygen as acceptor http://purl.obolibrary.org/obo/GO_0016724 CHEBI:26092 biolink:ChemicalSubstance phthalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26092 GO:0016725 biolink:MolecularActivity oxidoreductase activity, acting on CH or CH2 groups Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.17.-.- go-plus.json oxidoreductase activity, acting on CH or CH2 groups, other acceptors http://purl.obolibrary.org/obo/GO_0016725 GO:0016726 biolink:MolecularActivity oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. EC:1.17.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016726 CHEBI:26094 biolink:ChemicalSubstance benzenedicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26094 CHEBI:75051 biolink:ChemicalSubstance 2-amino-5-chlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_75051 chebi_ph7_3 GO:0016720 biolink:MolecularActivity delta12-fatty acid dehydrogenase activity Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O. MetaCyc:1.14.99.33-RXN|RHEA:23456|KEGG_REACTION:R05740|EC:1.14.99.33 go-plus.json linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)|D12-fatty acid dehydrogenase activity|linoleate delta-12-fatty acid acetylenase (desaturase) activity|delta12 fatty acid acetylenase activity|delta-12 fatty acid acetylenase activity|crepenynate synthase activity|linoleate delta12-fatty acid acetylenase (desaturase) http://purl.obolibrary.org/obo/GO_0016720 PR:000003425 biolink:Protein Hsp70 family chaperone A protein that is a stand alone version of the Hsp70 protein (Pfam:PF00012) domain, which comprises two major regions: an N-terminal ATP-binding domain and a C-terminal substrate-binding domain. go-plus.json http://purl.obolibrary.org/obo/PR_000003425 CHEBI:75052 biolink:ChemicalSubstance 3-dehydro-D-glucose-6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75052 chebi_ph7_3 GO:0016721 biolink:MolecularActivity oxidoreductase activity, acting on superoxide radicals as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor. EC:1.15.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016721 CHEBI:75050 biolink:ChemicalSubstance chromogenic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_75050 GO:0016722 biolink:MolecularActivity oxidoreductase activity, acting on metal ions Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered. Reactome:R-HSA-917805|EC:1.16.-.- go-plus.json oxidoreductase activity, reducing metal ions|oxidoreductase activity, oxidizing metal ions http://purl.obolibrary.org/obo/GO_0016722 CHEBI:90696 biolink:ChemicalSubstance thromboxane B2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90696 chebi_ph7_3 CHEBI:90697 biolink:ChemicalSubstance 11-oxo-ETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90697 chebi_ph7_3 CHEBI:75057 biolink:ChemicalSubstance 2-amino-5-chloro-cis,cis-muconate 6-semialdehyde zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75057 chebi_ph7_3 CHEBI:90694 biolink:ChemicalSubstance 12(S)-HHTrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90694 chebi_ph7_3 CHEBI:90680 biolink:ChemicalSubstance 12(S)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90680 chebi_ph7_3 CHEBI:51039 biolink:ChemicalSubstance dopamine uptake inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_51039 GO:0016738 biolink:MolecularActivity oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen. EC:1.19.6.- go-plus.json http://purl.obolibrary.org/obo/GO_0016738 GO:0016739 biolink:MolecularActivity obsolete oxidoreductase activity, acting on other substrates OBSOLETE. A grouping term for oxidoreductase that cannot be more accurately categorized. go-plus.json oxidoreductase activity, acting on other substrates http://purl.obolibrary.org/obo/GO_0016739 GO:0016734 biolink:MolecularActivity obsolete molybdenum-iron nitrogenase activity OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. go-plus.json molybdenum-iron nitrogenase activity http://purl.obolibrary.org/obo/GO_0016734 GO:0016735 biolink:MolecularActivity obsolete vanadium-iron nitrogenase activity OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. go-plus.json vanadium-iron nitrogenase activity http://purl.obolibrary.org/obo/GO_0016735 GO:0016736 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016736 GO:0016737 biolink:MolecularActivity oxidoreductase activity, acting on reduced flavodoxin as donor Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.19.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016737 GO:0016730 biolink:MolecularActivity oxidoreductase activity, acting on iron-sulfur proteins as donors Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.18.-.- go-plus.json oxidoreductase activity, acting on iron-sulphur proteins as donors http://purl.obolibrary.org/obo/GO_0016730 CHEBI:75062 biolink:ChemicalSubstance 1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75062 chebi_ph7_3 GO:0016731 biolink:MolecularActivity oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.18.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016731 CHEBI:75063 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75063 chebi_ph7_3 GO:0016732 biolink:MolecularActivity oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen. EC:1.18.6.- go-plus.json http://purl.obolibrary.org/obo/GO_0016732 GO:0016733 biolink:MolecularActivity obsolete iron-iron nitrogenase activity OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. go-plus.json iron-iron nitrogenase activity http://purl.obolibrary.org/obo/GO_0016733 CHEBI:75061 biolink:ChemicalSubstance trans-2-icosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75061 CHEBI:75066 biolink:ChemicalSubstance 1-acyl-2-linoleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75066 chebi_ph7_3 CHEBI:75067 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75067 chebi_ph7_3 CHEBI:75064 biolink:ChemicalSubstance trans-2-docosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75064 CHEBI:90688 biolink:ChemicalSubstance metformin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90688 CHEBI:75065 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75065 chebi_ph7_3 CHEBI:75068 biolink:ChemicalSubstance trans-2-tetracosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_75068 CHEBI:51031 biolink:ChemicalSubstance organic calcium salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_51031 CHEBI:75069 biolink:ChemicalSubstance 1-acyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75069 chebi_ph7_3 CHEBI:51026 biolink:ChemicalSubstance macrocycle go-plus.json http://purl.obolibrary.org/obo/CHEBI_51026 GO:0016709 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. Reactome:R-HSA-2162187|EC:1.14.13.-|Reactome:R-HSA-2162194 go-plus.json oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen http://purl.obolibrary.org/obo/GO_0016709 CHEBI:26066 biolink:ChemicalSubstance phosphonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26066 CHEBI:26069 biolink:ChemicalSubstance phosphonic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_26069 GO:0016705 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. EC:1.14.-.- go-plus.json oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous http://purl.obolibrary.org/obo/GO_0016705 GO:0016706 biolink:MolecularActivity 2-oxoglutarate-dependent dioxygenase activity Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. Reactome:R-HSA-6783455|Reactome:R-HSA-1234164|EC:1.14.11.- go-plus.json 2-oxoglutarate dioxygenase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors http://purl.obolibrary.org/obo/GO_0016706 GO:0016707 biolink:MolecularActivity gibberellin 3-beta-dioxygenase activity Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2. EC:1.14.11.15|RHEA:10104|MetaCyc:RXN1F-170 go-plus.json gibberellin 3beta-dioxygenase activity|(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)|gibberellin 3beta-hydroxylase activity|(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)|gibberellin 3-beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0016707 GO:0016708 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor. EC:1.14.12.- go-plus.json oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor http://purl.obolibrary.org/obo/GO_0016708 GO:0016701 biolink:MolecularActivity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor. EC:1.13.-.- go-plus.json oxygenase|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous http://purl.obolibrary.org/obo/GO_0016701 GO:0016702 biolink:MolecularActivity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor. Reactome:R-HSA-2161917|Reactome:R-HSA-2161775|Reactome:R-HSA-5164399|Reactome:R-HSA-9020274|Reactome:R-HSA-2161907|Reactome:R-HSA-9026408|EC:1.13.11.-|Reactome:R-HSA-9018880|Reactome:R-HSA-9026918 go-plus.json http://purl.obolibrary.org/obo/GO_0016702 UBERON:0008425 biolink:AnatomicalEntity mammary ridge A ridge of epidermal cells that will form the mammary placodes. go-plus.json mammary line|milk line|mammary gland ridge|mammary fold http://purl.obolibrary.org/obo/UBERON_0008425 CHEBI:75070 biolink:ChemicalSubstance 1-palmitoleoyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75070 GO:0016703 biolink:MolecularActivity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor. EC:1.13.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0016703 GO:0016704 biolink:MolecularActivity obsolete oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized. go-plus.json oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous http://purl.obolibrary.org/obo/GO_0016704 CHEBI:75074 biolink:ChemicalSubstance 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75074 UBERON:0008429 biolink:AnatomicalEntity cervical vertebral foramen A vertebral foramen that is part of a cervical vertebra. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008429 NCBITaxon:715962 biolink:OrganismalEntity dothideomyceta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_715962 GO:0016700 biolink:MolecularActivity obsolete oxidoreductase activity, acting on hydrogen as donor, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound. go-plus.json oxidoreductase activity, acting on hydrogen as donor, other acceptors http://purl.obolibrary.org/obo/GO_0016700 CHEBI:51022 biolink:ChemicalSubstance 1,3-dihydro-2H-imidazol-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_51022 chebi_ph7_3 CHEBI:75077 biolink:ChemicalSubstance N(1)-methylpseudouridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_75077 CHEBI:75078 biolink:ChemicalSubstance N(1)-methylpseudouridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75078 CHEBI:75075 biolink:ChemicalSubstance 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75075 CHEBI:75076 biolink:ChemicalSubstance 1-oleoyl-2-lauroyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75076 chebi_ph7_3 CHEBI:75079 biolink:ChemicalSubstance N(3)-methylcytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_75079 CHEBI:26078 biolink:ChemicalSubstance phosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26078 CHEBI:26079 biolink:ChemicalSubstance phosphoric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_26079 CHEBI:26073 biolink:ChemicalSubstance phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_26073 GO:0016716 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor. EC:1.14.18.- go-plus.json http://purl.obolibrary.org/obo/GO_0016716 GO:0016717 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water. EC:1.14.19.- go-plus.json http://purl.obolibrary.org/obo/GO_0016717 GO:0016718 biolink:MolecularActivity obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized. go-plus.json oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous http://purl.obolibrary.org/obo/GO_0016718 GO:0016719 biolink:MolecularActivity carotene 7,8-desaturase activity Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O. RHEA:15701|MetaCyc:1.14.99.30-RXN|EC:1.3.5.6 go-plus.json carotene,hydrogen-donor:oxygen oxidoreductase activity|zeta-carotene desaturase activity http://purl.obolibrary.org/obo/GO_0016719 GO:0089700 biolink:BiologicalProcess protein kinase D signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound. go-plus.json PKD signal transduction|protein kinase D signal transduction|PKD signaling cascade|protein kinase D signalling cascade|protein kinase D signaling cascade http://purl.obolibrary.org/obo/GO_0089700 GO:0089701 biolink:CellularComponent U2AF complex A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point. go-plus.json U2AF|U2 accessory factor http://purl.obolibrary.org/obo/GO_0089701 GO:0016712 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor. Reactome:R-HSA-211966|UM-BBD_enzymeID:e0551|EC:1.14.14.- go-plus.json microsomal p450 activity|microsomal monooxygenase activity|substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)|flavoprotein monooxygenase activity|aryl-4-monooxygenase activity|xenobiotic monooxygenase activity|microsomal P-450|flavoprotein-linked monooxygenase activity|cytochrome P450 CYP19|cytochrome p450 activity|aryl hydrocarbon hydroxylase activity|unspecific monooxygenase activity http://purl.obolibrary.org/obo/GO_0016712 GO:0089702 biolink:MolecularActivity undecaprenyl-phosphate glucose phosphotransferase activity Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol. go-plus.json http://purl.obolibrary.org/obo/GO_0089702 GO:0016713 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor. EC:1.14.15.- go-plus.json oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen http://purl.obolibrary.org/obo/GO_0016713 GO:0016714 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor. EC:1.14.16.- go-plus.json http://purl.obolibrary.org/obo/GO_0016714 GO:0089703 biolink:BiologicalProcess L-aspartate transmembrane export from vacuole The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089703 CHEBI:26082 biolink:ChemicalSubstance phosphorus molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_26082 GO:0089704 biolink:BiologicalProcess L-glutamate transmembrane export from vacuole The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089704 GO:0016715 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor. EC:1.14.17.- go-plus.json http://purl.obolibrary.org/obo/GO_0016715 GO:0089705 biolink:BiologicalProcess protein localization to outer membrane A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089705 GO:0089706 biolink:BiologicalProcess L-ornithine transmembrane export from vacuole The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089706 CHEBI:75085 biolink:ChemicalSubstance N(4)-acetylcytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_75085 GO:0016710 biolink:MolecularActivity trans-cinnamate 4-monooxygenase activity Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O. RHEA:10608|EC:1.14.14.91|MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN go-plus.json cinnamate 4-hydroxylase activity|oxygenase, cinnamate 4-mono-|cinnamic acid 4-monooxygenase activity|CA4H activity|trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)|hydroxylase, cinnamate 4-|cinnamic 4-hydroxylase activity|trans-cinnamic acid 4-hydroxylase activity|cinnamic acid p-hydroxylase activity|cinnamic acid 4-hydroxylase activity|t-cinnamic acid hydroxylase activity|cytochrome P450 cinnamate 4-hydroxylase activity|cinnamate 4-monooxygenase activity|cinnamate hydroxylase activity|trans-cinnamate 4-hydroxylase activity http://purl.obolibrary.org/obo/GO_0016710 GO:0089707 biolink:BiologicalProcess L-lysine transmembrane export from vacuole The directed movement of L-lysine out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089707 GO:0016711 biolink:MolecularActivity flavonoid 3'-monooxygenase activity Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O. RHEA:16337|MetaCyc:FLAVONOID-3-MONOOXYGENASE-RXN|EC:1.14.14.82 go-plus.json flavonoid 3-hydroxylase|flavonoid 3-monooxygenase|NADPH:flavonoid-3'-hydroxylase activity|flavonoid 3'-hydroxylase activity|flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating) http://purl.obolibrary.org/obo/GO_0016711 GO:0089708 biolink:BiologicalProcess L-histidine transmembrane export from vacuole The directed movement of L-histidine out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089708 CHEBI:75083 biolink:ChemicalSubstance N(3)-methylcytidine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_75083 GO:0089709 biolink:BiologicalProcess L-histidine transmembrane transport The directed movement of L-histidine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0089709 CHEBI:51013 biolink:ChemicalSubstance beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_51013 CHEBI:51014 biolink:ChemicalSubstance (S)-styrene oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_51014 chebi_ph7_3 CHEBI:51006 biolink:ChemicalSubstance unsaturated fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_51006 CHEBI:26044 biolink:ChemicalSubstance phosphinic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_26044 CHEBI:26045 biolink:ChemicalSubstance phosphite ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_26045 CHEBI:75091 biolink:ChemicalSubstance aclacinomycin N go-plus.json http://purl.obolibrary.org/obo/CHEBI_75091 GO:1905500 biolink:BiologicalProcess obsolete heteroreceptor complex assembly OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a heteroreceptor complex. go-plus.json heteroreceptor complex formation http://purl.obolibrary.org/obo/GO_1905500 UBERON:0008404 biolink:AnatomicalEntity proximal tubular epithelium The cells lining the proximal tubule are cuboidal epithelial cells with deep basal membrane invaginations that provide a large basal surface area. The long microvilli (the brush border) lining the tubule lumen, maximize luminal surface area and make these cells ideally suited for both reabsorptive and secretory functions. go-plus.json epithelium of proximal renal tubule|proximal renal tubule epithelium|proximale tubular epithelium|proximal tubule epithelium|epithelium of proximal convoluted tubule http://purl.obolibrary.org/obo/UBERON_0008404 GO:1905501 biolink:BiologicalProcess obsolete heteroreceptor complex disassembly OBSOLETE. The disaggregation of a heteroreceptor complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_1905501 GO:1905502 biolink:MolecularActivity acetyl-CoA binding Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component. go-plus.json acetyl-coenzyme A binding http://purl.obolibrary.org/obo/GO_1905502 GO:1905503 biolink:BiologicalProcess regulation of motile cilium assembly Any process that modulates the frequency, rate or extent of motile cilium assembly. go-plus.json regulation of motile primary cilia formation|regulation of nodal cilium formation|regulation of motile primary cilium formation|regulation of nodal cilium assembly|regulation of motile primary cilia assembly|regulation of motile primary cilium assembly http://purl.obolibrary.org/obo/GO_1905503 GO:1905504 biolink:BiologicalProcess negative regulation of motile cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly. go-plus.json downregulation of nodal cilium formation|down regulation of motile primary cilia formation|downregulation of motile primary cilium assembly|inhibition of motile primary cilium assembly|inhibition of nodal cilium assembly|down regulation of nodal cilium formation|down regulation of motile primary cilium assembly|negative regulation of motile primary cilium assembly|down regulation of motile primary cilium formation|inhibition of nodal cilium formation|down regulation of nodal cilium assembly|down regulation of motile primary cilia assembly|downregulation of motile primary cilium formation|downregulation of nodal cilium assembly|downregulation of motile primary cilia assembly|down-regulation of motile primary cilia formation|negative regulation of motile primary cilia formation|negative regulation of nodal cilium formation|negative regulation of motile primary cilium formation|down-regulation of motile primary cilium formation|down-regulation of nodal cilium formation|negative regulation of nodal cilium assembly|down-regulation of motile primary cilium assembly|down-regulation of nodal cilium assembly|inhibition of motile primary cilium formation|negative regulation of motile primary cilia assembly|down-regulation of motile primary cilia assembly|inhibition of motile primary cilia assembly|downregulation of motile primary cilia formation|inhibition of motile primary cilia formation http://purl.obolibrary.org/obo/GO_1905504 CHEBI:75096 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75096 GO:1905505 biolink:BiologicalProcess positive regulation of motile cilium assembly Any process that activates or increases the frequency, rate or extent of motile cilium assembly. go-plus.json up-regulation of motile primary cilium formation|up regulation of motile primary cilium assembly|up-regulation of nodal cilium assembly|up-regulation of motile primary cilia assembly|upregulation of motile primary cilia formation|upregulation of nodal cilium formation|upregulation of motile primary cilium formation|upregulation of motile primary cilium assembly|upregulation of nodal cilium assembly|activation of motile primary cilia formation|upregulation of motile primary cilia assembly|up-regulation of motile primary cilia formation|activation of motile primary cilium assembly|positive regulation of motile primary cilium assembly|activation of motile primary cilium formation|up-regulation of nodal cilium formation|up regulation of motile primary cilium formation|up-regulation of motile primary cilium assembly|up regulation of nodal cilium assembly|activation of motile primary cilia assembly|positive regulation of motile primary cilium formation|positive regulation of nodal cilium assembly|up regulation of motile primary cilia assembly|activation of nodal cilium formation|positive regulation of motile primary cilia assembly|positive regulation of motile primary cilia formation|activation of nodal cilium assembly|up regulation of motile primary cilia formation|positive regulation of nodal cilium formation|up regulation of nodal cilium formation http://purl.obolibrary.org/obo/GO_1905505 CHEBI:75093 biolink:ChemicalSubstance aclacinomycin Y go-plus.json http://purl.obolibrary.org/obo/CHEBI_75093 UBERON:0008408 biolink:AnatomicalEntity distal tubular epithelium An epithelium that is part of a distal tubule. go-plus.json distal tubule epithelium http://purl.obolibrary.org/obo/UBERON_0008408 GO:1905506 biolink:CellularComponent gerontoplast stroma Any plastid stroma that is part of a gerontoplast. go-plus.json http://purl.obolibrary.org/obo/GO_1905506 CHEBI:41688 biolink:ChemicalSubstance crystal violet go-plus.json http://purl.obolibrary.org/obo/CHEBI_41688 GO:1905507 biolink:BiologicalProcess obsolete cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic G2 DNA damage checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_1905507 CHEBI:75099 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75099 GO:1905508 biolink:BiologicalProcess protein localization to microtubule organizing center A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center. go-plus.json protein localisation in microtubule organizing center|protein localisation to microtubule organizing center|protein localization in microtubule organizing center http://purl.obolibrary.org/obo/GO_1905508 GO:1905509 biolink:BiologicalProcess protein localization to interphase microtubule organizing center A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center. go-plus.json protein localisation to interphase microtubule organizing center|protein localisation in interphase microtubule organizing center|protein localization in interphase microtubule organizing center http://purl.obolibrary.org/obo/GO_1905509 GO:0051104 biolink:BiologicalProcess DNA-dependent DNA replication DNA ligation The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication. go-plus.json DNA ligation during DNA-dependent DNA replication|DNA ligation involved in DNA-dependent DNA replication http://purl.obolibrary.org/obo/GO_0051104 GO:0051105 biolink:BiologicalProcess regulation of DNA ligation Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0051105 GO:0051102 biolink:BiologicalProcess DNA ligation involved in DNA recombination The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination. go-plus.json DNA ligation during DNA recombination http://purl.obolibrary.org/obo/GO_0051102 GO:0051103 biolink:BiologicalProcess DNA ligation involved in DNA repair The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair. go-plus.json DNA ligation during DNA repair http://purl.obolibrary.org/obo/GO_0051103 GO:0051108 biolink:MolecularActivity carnitine-CoA ligase activity Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA. MetaCyc:DCARNCOALIG-RXN|RHEA:30543 go-plus.json crotonobetaine/carnitine-CoA ligase activity|carnitine synthetase activity http://purl.obolibrary.org/obo/GO_0051108 GO:0051109 biolink:MolecularActivity crotonobetaine-CoA ligase activity Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA. MetaCyc:CROTCOALIG-RXN|RHEA:30079 go-plus.json crotonobetaine/carnitine-CoA ligase activity|crotonobetaine-CoA synthase activity http://purl.obolibrary.org/obo/GO_0051109 GO:0051106 biolink:BiologicalProcess positive regulation of DNA ligation Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. go-plus.json upregulation of DNA ligation|stimulation of DNA ligation|up-regulation of DNA ligation|activation of DNA ligation|up regulation of DNA ligation http://purl.obolibrary.org/obo/GO_0051106 GO:0051107 biolink:BiologicalProcess negative regulation of DNA ligation Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. go-plus.json downregulation of DNA ligation|down regulation of DNA ligation|inhibition of DNA ligation|down-regulation of DNA ligation http://purl.obolibrary.org/obo/GO_0051107 CHEBI:41674 biolink:ChemicalSubstance cyclohexane-1,2-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_41674 chebi_ph7_3 CHEBI:26057 biolink:ChemicalSubstance phosphoglycosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26057 NCBITaxon:715989 biolink:OrganismalEntity sordariomyceta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_715989 CHEBI:26051 biolink:ChemicalSubstance phosphoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26051 GO:1905520 biolink:BiologicalProcess positive regulation of presynaptic active zone assembly Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly. go-plus.json upregulation of pre-synaptic active zone component formation|activation of pre-synaptic active zone component assembly|up regulation of pre-synaptic active zone assembly|activation of pre-synaptic active zone assembly|upregulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone assembly|up-regulation of pre-synaptic active zone component assembly|upregulation of presynaptic active zone formation|up-regulation of pre-synaptic active zone component formation|up regulation of presynaptic active zone assembly|activation of pre-synaptic active zone formation|up-regulation of pre-synaptic active zone formation|activation of pre-synaptic active zone component formation|upregulation of pre-synaptic active zone component assembly|up-regulation of pre-synaptic active zone assembly|up regulation of presynaptic active zone formation|activation of presynaptic active zone formation|positive regulation of presynaptic active zone formation|positive regulation of pre-synaptic active zone component formation|upregulation of presynaptic active zone assembly|up regulation of pre-synaptic active zone component formation|positive regulation of pre-synaptic active zone formation|upregulation of pre-synaptic active zone assembly|up regulation of pre-synaptic active zone component assembly|up regulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone component assembly|up-regulation of presynaptic active zone formation|activation of presynaptic active zone assembly|up-regulation of presynaptic active zone assembly http://purl.obolibrary.org/obo/GO_1905520 GO:1905510 biolink:BiologicalProcess negative regulation of myosin II filament assembly Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly. go-plus.json downregulation of myosin II polymerization|down regulation of myosin II polymerization|inhibition of myosin II filament assembly|inhibition of myosin II polymerization|down regulation of myosin II filament assembly|downregulation of myosin II filament assembly|down-regulation of myosin II polymerization|negative regulation of myosin II polymerization|down-regulation of myosin II filament assembly http://purl.obolibrary.org/obo/GO_1905510 GO:1905511 biolink:BiologicalProcess positive regulation of myosin II filament assembly Any process that activates or increases the frequency, rate or extent of myosin II filament assembly. go-plus.json up-regulation of myosin II filament assembly|upregulation of myosin II polymerization|upregulation of myosin II filament assembly|up-regulation of myosin II polymerization|activation of myosin II polymerization|up regulation of myosin II filament assembly|activation of myosin II filament assembly|positive regulation of myosin II polymerization|up regulation of myosin II polymerization http://purl.obolibrary.org/obo/GO_1905511 GO:1905512 biolink:BiologicalProcess regulation of short-term synaptic potentiation Any process that modulates the frequency, rate or extent of short-term synaptic potentiation. go-plus.json regulation of synaptic facilitation http://purl.obolibrary.org/obo/GO_1905512 GO:1905513 biolink:BiologicalProcess negative regulation of short-term synaptic potentiation Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation. go-plus.json downregulation of short-term synaptic potentiation|down regulation of short-term synaptic potentiation|inhibition of short-term synaptic potentiation|down regulation of synaptic facilitation|downregulation of synaptic facilitation|negative regulation of synaptic facilitation|down-regulation of synaptic facilitation|down-regulation of short-term synaptic potentiation|inhibition of synaptic facilitation http://purl.obolibrary.org/obo/GO_1905513 GO:1905514 biolink:BiologicalProcess positive regulation of short-term synaptic potentiation Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation. go-plus.json upregulation of synaptic facilitation|upregulation of short-term synaptic potentiation|up regulation of synaptic facilitation|activation of synaptic facilitation|positive regulation of synaptic facilitation|up-regulation of short-term synaptic potentiation|activation of short-term synaptic potentiation|up-regulation of synaptic facilitation|up regulation of short-term synaptic potentiation http://purl.obolibrary.org/obo/GO_1905514 GO:1905515 biolink:BiologicalProcess non-motile cilium assembly The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. go-plus.json non-motile cilium formation|immotile primary cilium assembly|nonmotile primary cilium assembly|sensory cilium assembly|nonmotile cilium formation|sensory cilium biogenesis|nonmotile cilium assembly|nonmotile primary cilia assembly http://purl.obolibrary.org/obo/GO_1905515 GO:1905516 biolink:BiologicalProcess positive regulation of fertilization Any process that activates or increases the frequency, rate or extent of fertilization. go-plus.json up-regulation of fertilization|up regulation of syngamy|activation of syngamy|positive regulation of syngamy|upregulation of fertilization|up-regulation of syngamy|up regulation of fertilization|activation of fertilization|upregulation of syngamy http://purl.obolibrary.org/obo/GO_1905516 GO:1905517 biolink:BiologicalProcess macrophage migration The orderly movement of a macrophage from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_1905517 GO:1905518 biolink:BiologicalProcess regulation of presynaptic active zone assembly Any process that modulates the frequency, rate or extent of presynaptic active zone assembly. go-plus.json regulation of presynaptic active zone formation|regulation of pre-synaptic active zone component assembly|regulation of pre-synaptic active zone component formation|regulation of pre-synaptic active zone assembly|regulation of pre-synaptic active zone formation http://purl.obolibrary.org/obo/GO_1905518 GO:1905519 biolink:BiologicalProcess negative regulation of presynaptic active zone assembly Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly. go-plus.json down regulation of presynaptic active zone formation|inhibition of pre-synaptic active zone component assembly|downregulation of presynaptic active zone formation|inhibition of pre-synaptic active zone assembly|downregulation of presynaptic active zone assembly|down-regulation of pre-synaptic active zone component formation|negative regulation of pre-synaptic active zone component formation|down regulation of presynaptic active zone assembly|down regulation of pre-synaptic active zone component assembly|negative regulation of pre-synaptic active zone formation|inhibition of presynaptic active zone assembly|down-regulation of pre-synaptic active zone formation|negative regulation of presynaptic active zone formation|downregulation of pre-synaptic active zone component assembly|down-regulation of presynaptic active zone formation|downregulation of pre-synaptic active zone component formation|down regulation of pre-synaptic active zone assembly|inhibition of presynaptic active zone formation|downregulation of pre-synaptic active zone formation|down regulation of pre-synaptic active zone component formation|downregulation of pre-synaptic active zone assembly|negative regulation of pre-synaptic active zone component assembly|down-regulation of pre-synaptic active zone component assembly|down regulation of pre-synaptic active zone formation|inhibition of pre-synaptic active zone formation|inhibition of pre-synaptic active zone component formation|down-regulation of presynaptic active zone assembly|negative regulation of pre-synaptic active zone assembly|down-regulation of pre-synaptic active zone assembly http://purl.obolibrary.org/obo/GO_1905519 GO:0051100 biolink:BiologicalProcess negative regulation of binding Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. go-plus.json down-regulation of binding|inhibition of binding|down regulation of binding|downregulation of binding http://purl.obolibrary.org/obo/GO_0051100 GO:0051101 biolink:BiologicalProcess regulation of DNA binding Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). go-plus.json http://purl.obolibrary.org/obo/GO_0051101 GO:0002188 biolink:BiologicalProcess translation reinitiation A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon. go-plus.json http://purl.obolibrary.org/obo/GO_0002188 GO:0002189 biolink:CellularComponent ribose phosphate diphosphokinase complex A protein complex having ribose phosphate diphosphokinase activity. go-plus.json PRPP synthetase complex|phosphoribosylpyrophosphate synthetase complex http://purl.obolibrary.org/obo/GO_0002189 GO:0099098 biolink:BiologicalProcess microtubule polymerization based movement The movement of a cellular component as a result of microtubule polymerization. go-plus.json http://purl.obolibrary.org/obo/GO_0099098 GO:0099099 biolink:MolecularActivity G-protein gated ion channel activity An ion channel activity that is gated by binding of a G-protein beta-gamma dimer. go-plus.json http://purl.obolibrary.org/obo/GO_0099099 GO:0099096 biolink:CellularComponent vestibular calyx terminal The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell. go-plus.json http://purl.obolibrary.org/obo/GO_0099096 GO:0002184 biolink:BiologicalProcess cytoplasmic translational termination The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon. go-plus.json http://purl.obolibrary.org/obo/GO_0002184 GO:0002185 biolink:CellularComponent creatine kinase complex A protein complex having creatine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0002185 GO:0099097 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099097 GO:0099094 biolink:MolecularActivity ligand-gated cation channel activity Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0099094 GO:0002186 biolink:CellularComponent cytosolic creatine kinase complex A dimeric protein complex having creatine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0002186 GO:0099095 biolink:MolecularActivity ligand-gated anion channel activity Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0099095 GO:0002187 biolink:CellularComponent mitochondrial creatine kinase complex An octomeric protein complex having creatine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0002187 GO:0099092 biolink:CellularComponent postsynaptic density, intracellular component A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. go-plus.json http://purl.obolibrary.org/obo/GO_0099092 goslim_synapse GO:0002180 biolink:CellularComponent 5-lipoxygenase complex An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0002180 GO:0002181 biolink:BiologicalProcess cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0002181 goslim_pombe|goslim_yeast|goslim_drosophila GO:0099093 biolink:BiologicalProcess calcium export from the mitochondrion A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol. go-plus.json calcium ion transmembrane export from mitochondrion|mitochondrial calcium release|mitochondrial calcium ion export http://purl.obolibrary.org/obo/GO_0099093 GO:0099090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0099090 GO:0002182 biolink:BiologicalProcess cytoplasmic translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0002182 GO:0099091 biolink:CellularComponent postsynaptic specialization, intracellular component A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. go-plus.json http://purl.obolibrary.org/obo/GO_0099091 goslim_synapse GO:0002183 biolink:BiologicalProcess cytoplasmic translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0002183 GO:0002190 biolink:BiologicalProcess cap-independent translational initiation The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation. go-plus.json http://purl.obolibrary.org/obo/GO_0002190 GO:0002199 biolink:CellularComponent zona pellucida receptor complex A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction. go-plus.json sperm protein complex I http://purl.obolibrary.org/obo/GO_0002199 GO:0002195 biolink:BiologicalProcess 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0002195 GO:0002196 biolink:MolecularActivity Ser-tRNA(Ala) hydrolase activity Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala). go-plus.json http://purl.obolibrary.org/obo/GO_0002196 GO:0002197 biolink:CellularComponent xanthine dehydrogenase complex A homodimeric protein complex having xanthine dehydrogenase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0002197 GO:0002198 biolink:BiologicalProcess obsolete S/G2 transition of mitotic cell cycle OBSOLETE. The transition from a cell in the S phase to the G2 phase. go-plus.json S/G2 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0002198 GO:0002191 biolink:BiologicalProcess cap-dependent translational initiation The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. go-plus.json http://purl.obolibrary.org/obo/GO_0002191 GO:0002192 biolink:BiologicalProcess IRES-dependent translational initiation of linear mRNA The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation. go-plus.json http://purl.obolibrary.org/obo/GO_0002192 GO:0002193 biolink:CellularComponent MAML1-RBP-Jkappa- ICN1 complex A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML1-CSL-ICN1|MAML1-RBP-Jkappa-Notch1 complex|MAML1-CSL-Notch1 complex http://purl.obolibrary.org/obo/GO_0002193 GO:0002194 biolink:BiologicalProcess hepatocyte cell migration The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes. go-plus.json http://purl.obolibrary.org/obo/GO_0002194 CHEBI:145267 biolink:ChemicalSubstance PE(0:0/22:4) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145267 CHEBI:145269 biolink:ChemicalSubstance PE(0:0/22:5) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145269 GO:0099078 biolink:CellularComponent BORC complex A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors. go-plus.json http://purl.obolibrary.org/obo/GO_0099078 GO:0002166 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002166 GO:0099079 biolink:CellularComponent actin body An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin. go-plus.json http://purl.obolibrary.org/obo/GO_0099079 PATO:0015006 biolink:OntologyClass polymeric A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array. go-plus.json http://purl.obolibrary.org/obo/PATO_0015006 GO:0002167 biolink:CellularComponent VRK3/VHR/ERK complex A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0002167 GO:0002168 biolink:BiologicalProcess instar larval development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0002168 GO:0099076 biolink:BiologicalProcess mitochondrion to peroxisome transport Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0099076 GO:0002169 biolink:CellularComponent 3-methylcrotonyl-CoA carboxylase complex, mitochondrial A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA. go-plus.json mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme|mitochondrial methylcrotonoyl-CoA carboxylase complex|mitochondrial MCCC complex http://purl.obolibrary.org/obo/GO_0002169 GO:0099077 biolink:MolecularActivity histone-dependent DNA binding DNA-binding activity that is dependent on binding to a histone. go-plus.json http://purl.obolibrary.org/obo/GO_0099077 GO:0099074 biolink:BiologicalProcess mitochondrion to lysosome transport Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0099074 GO:0002162 biolink:MolecularActivity dystroglycan binding Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal). go-plus.json beta-dystroglycan binding|alpha-dystroglycan binding http://purl.obolibrary.org/obo/GO_0002162 GO:0099075 biolink:BiologicalProcess mitochondrion-derived vesicle mediated transport Transport from the mitochondrion, mediated by mitochondrion derived vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0099075 GO:0002163 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002163 GO:0099072 biolink:BiologicalProcess regulation of postsynaptic membrane neurotransmitter receptor levels Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0099072 goslim_synapse GO:0002164 biolink:BiologicalProcess larval development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. go-plus.json http://purl.obolibrary.org/obo/GO_0002164 CHEBI:145260 biolink:ChemicalSubstance PE(0:0/20:3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145260 GO:0099073 biolink:CellularComponent mitochondrion-derived vesicle A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae. go-plus.json MDV http://purl.obolibrary.org/obo/GO_0099073 GO:0002165 biolink:BiologicalProcess instar larval or pupal development The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0002165 GO:0099070 biolink:CellularComponent static microtubule bundle A microtubule bundle that has a constant length, and in which microtubule sliding does not take place. go-plus.json quiescent cell MT bundle|Q-MT bundle|quiescent cell microtubule bundle http://purl.obolibrary.org/obo/GO_0099070 CHEBI:145262 biolink:ChemicalSubstance PE(0:0/20:5) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145262 GO:0099071 biolink:CellularComponent dynamic microtubule bundle A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place. go-plus.json http://purl.obolibrary.org/obo/GO_0099071 GO:0002160 biolink:BiologicalProcess desmosome maintenance The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0002160 CHEBI:145264 biolink:ChemicalSubstance lysophosphatidylethanolamine 22:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145264 GO:0002161 biolink:MolecularActivity aminoacyl-tRNA editing activity The hydrolysis of an incorrectly aminoacylated tRNA. go-plus.json aminoacyl-tRNA hydrolysis activity|amino acid proofreading activity http://purl.obolibrary.org/obo/GO_0002161 CHEBI:145265 biolink:ChemicalSubstance PE(0:0/22:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145265 CHEBI:90616 biolink:ChemicalSubstance N(6)-methyl-2'-deoxyadenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90616 chebi_ph7_3 CHEBI:90618 biolink:ChemicalSubstance C-terminal Gly-Gly-AMP(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_90618 chebi_ph7_3 CHEBI:90619 biolink:ChemicalSubstance C-terminal N-glycylaminoethanethioic S-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90619 chebi_ph7_3 CHEBI:90615 biolink:ChemicalSubstance 2'-deoxyadenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90615 chebi_ph7_3 CHEBI:90610 biolink:ChemicalSubstance O-[S-2,3-dihydroxybenzoylpantetheine-4'-phosphoryl]-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90610 chebi_ph7_3 CHEBI:145255 biolink:ChemicalSubstance lysophosphatidylethanolamine 18:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145255 CHEBI:145257 biolink:ChemicalSubstance PE(0:0/18:3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145257 GO:0002177 biolink:CellularComponent manchette A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0002177 GO:0099089 biolink:BiologicalProcess establishment of endoplasmic reticulum localization to postsynapse The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine. go-plus.json establishment of ER localization to postsynapse http://purl.obolibrary.org/obo/GO_0099089 goslim_synapse GO:0002178 biolink:CellularComponent palmitoyltransferase complex A protein complex with palmitoyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0002178 GO:0002179 biolink:CellularComponent homodimeric serine palmitoyltransferase complex A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine. go-plus.json http://purl.obolibrary.org/obo/GO_0002179 GO:0099087 biolink:BiologicalProcess anterograde axonal transport of messenger ribonucleoprotein complex The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse. go-plus.json anterograde axonal transport of mRNA RNP complex http://purl.obolibrary.org/obo/GO_0099087 goslim_synapse GO:0099088 biolink:BiologicalProcess axonal transport of messenger ribonucleoprotein complex The directed movement of a messenger ribonucleoprotein complex along microtubules in axons. go-plus.json axonal transport of mRNA RNP complex http://purl.obolibrary.org/obo/GO_0099088 goslim_synapse GO:0002173 biolink:MolecularActivity low-affinity IgM receptor activity Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json low affinity IgM receptor activity http://purl.obolibrary.org/obo/GO_0002173 GO:0099085 biolink:MolecularActivity DIF dechlorinase activity Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-. go-plus.json 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one 3(5)-dechlorinase activity|DIF-1 dechlorinase activity|differentiation-inducing factor 1 dechlorinase activity|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 3(5)-dechlorinase activity|DIF-1 3(5)-dechlorinase activity|differentiation-inducing factor dechlorinase activity http://purl.obolibrary.org/obo/GO_0099085 GO:0002174 biolink:BiologicalProcess mammary stem cell proliferation The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ. go-plus.json http://purl.obolibrary.org/obo/GO_0002174 GO:0099086 biolink:CellularComponent synaptonemal structure A proteinaceous scaffold found between homologous chromosomes during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0099086 GO:0002175 biolink:BiologicalProcess protein localization to paranode region of axon A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon. go-plus.json protein localisation to paranode region of axon http://purl.obolibrary.org/obo/GO_0002175 GO:0099083 biolink:BiologicalProcess retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0099083 goslim_synapse GO:0002176 biolink:BiologicalProcess male germ cell proliferation The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0002176 CHEBI:145250 biolink:ChemicalSubstance PE(0:0/16:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145250 GO:0099084 biolink:BiologicalProcess postsynaptic specialization organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane. go-plus.json post-synaptic specialization organization|postsynaptic specialization organisation|post synaptic specialization organization http://purl.obolibrary.org/obo/GO_0099084 goslim_synapse CHEBI:145251 biolink:ChemicalSubstance PE(0:0/14:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145251 GO:0099081 biolink:CellularComponent supramolecular polymer A polymeric supramolecular structure. go-plus.json http://purl.obolibrary.org/obo/GO_0099081 GO:0099082 biolink:BiologicalProcess retrograde trans-synaptic signaling by neuropeptide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0099082 goslim_synapse GO:0002170 biolink:MolecularActivity high-affinity IgA receptor activity Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json high affinity IgA receptor activity http://purl.obolibrary.org/obo/GO_0002170 CHEBI:145252 biolink:ChemicalSubstance PE(0:0/18:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145252 GO:0002171 biolink:MolecularActivity low-affinity IgA receptor activity Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json low affinity IgA receptor activity http://purl.obolibrary.org/obo/GO_0002171 GO:0002172 biolink:MolecularActivity high-affinity IgM receptor activity Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json high affinity IgM receptor activity http://purl.obolibrary.org/obo/GO_0002172 GO:0099080 biolink:CellularComponent supramolecular complex A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0099080 CHEBI:90605 biolink:ChemicalSubstance monodecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90605 chebi_ph7_3 CHEBI:90602 biolink:ChemicalSubstance uridylyl-L-tyrosine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90602 chebi_ph7_3 GO:0002148 biolink:BiologicalProcess hypochlorous acid metabolic process The chemical reactions and pathways involving hypochlorous acid. go-plus.json HClO metabolic process|hypochlorous acid metabolism|hypochlorite metabolic process|HOCl metabolic process http://purl.obolibrary.org/obo/GO_0002148 CHEBI:145245 biolink:ChemicalSubstance lysophosphatidylethanolamine 14:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145245 GO:0002149 biolink:BiologicalProcess hypochlorous acid biosynthetic process The chemical reactions and pathways resulting in the formation of hypochlorous acid. go-plus.json hypochlorous acid biosynthesis|HOCl biosynthetic process|HClO biosynthetic process|hypochlorite biosynthetic process http://purl.obolibrary.org/obo/GO_0002149 CHEBI:145247 biolink:ChemicalSubstance lysophosphatidylethanolamine 16:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_145247 GO:0002144 biolink:CellularComponent cytosolic tRNA wobble base thiouridylase complex A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets. go-plus.json tRNA thiouridylase|Cut1-Cut2 complex http://purl.obolibrary.org/obo/GO_0002144 GO:0002145 biolink:MolecularActivity 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+). MetaCyc:RXN0-3543|RHEA:27914 go-plus.json HMP-PP diphosphatase|HMP-PP pyrophosphatase http://purl.obolibrary.org/obo/GO_0002145 GO:0002146 biolink:BiologicalProcess obsolete steroid hormone receptor import into nucleus OBSOLETE. The directed movement of a steroid hormone receptor into the nucleus. go-plus.json steroid hormone receptor nuclear translocation http://purl.obolibrary.org/obo/GO_0002146 GO:0002147 biolink:BiologicalProcess obsolete glucocorticoid receptor import into nucleus OBSOLETE. The directed movement of a glucocorticoid receptor into the nucleus. go-plus.json glucocorticoid receptor nuclear translocation http://purl.obolibrary.org/obo/GO_0002147 GO:0002140 biolink:CellularComponent stereocilia tip link A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia. go-plus.json http://purl.obolibrary.org/obo/GO_0002140 GO:0002141 biolink:CellularComponent stereocilia ankle link A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia. go-plus.json http://purl.obolibrary.org/obo/GO_0002141 GO:0002142 biolink:CellularComponent stereocilia ankle link complex A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin. go-plus.json http://purl.obolibrary.org/obo/GO_0002142 GO:0002143 biolink:BiologicalProcess tRNA wobble position uridine thiolation The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. go-plus.json wobble position s2U biosynthesis|tRNA wobble uridine thiolation http://purl.obolibrary.org/obo/GO_0002143 CHEBI:145240 biolink:ChemicalSubstance 2-methylpyrrolidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_145240 GO:0016789 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016789 GO:0016785 biolink:MolecularActivity selenotransferase activity Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor). EC:2.9.1.- go-plus.json transferase activity, transferring selenium-containing groups http://purl.obolibrary.org/obo/GO_0016785 GO:0016786 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016786 GO:0016787 biolink:MolecularActivity hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Reactome:R-HSA-6788295|Reactome:R-HSA-5694583|Reactome:R-HSA-1236938|Reactome:R-HSA-8938314|Reactome:R-HSA-6786190|Reactome:R-HSA-2029475|Reactome:R-HSA-5695964|EC:3.-.-.-|Reactome:R-HSA-8952137 go-plus.json http://purl.obolibrary.org/obo/GO_0016787 goslim_mouse|goslim_candida|goslim_yeast|goslim_plant|goslim_pir|goslim_metagenomics|goslim_aspergillus|goslim_chembl GO:0016788 biolink:MolecularActivity hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond. Reactome:R-HSA-9023617|Reactome:R-HSA-9023619|EC:3.1.-.-|Reactome:R-HSA-162729 go-plus.json esterase activity http://purl.obolibrary.org/obo/GO_0016788 goslim_chembl GO:0016781 biolink:MolecularActivity phosphotransferase activity, paired acceptors Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors. EC:2.7.9.- go-plus.json http://purl.obolibrary.org/obo/GO_0016781 GO:0016782 biolink:MolecularActivity transferase activity, transferring sulphur-containing groups Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor). EC:2.8.-.- go-plus.json transferase activity, transferring sulphur-containing groups http://purl.obolibrary.org/obo/GO_0016782 CHEBI:90631 biolink:ChemicalSubstance 5-hydroperoxy-15-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90631 chebi_ph7_3 GO:0016783 biolink:MolecularActivity sulfurtransferase activity Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). Reactome:R-HSA-1614618|Reactome:R-HSA-6782264|EC:2.8.1.-|Reactome:R-HSA-947538 go-plus.json sulphurtransferase activity|tRNA sulfurtransferase activity http://purl.obolibrary.org/obo/GO_0016783 CHEBI:90632 biolink:ChemicalSubstance 5(S)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90632 chebi_ph7_3 GO:0016784 biolink:MolecularActivity 3-mercaptopyruvate sulfurtransferase activity Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate. Reactome:R-HSA-9013533|RHEA:21740|Reactome:R-HSA-9012721|EC:2.8.1.2|MetaCyc:MERCAPYSTRANS-RXN|Reactome:R-HSA-9034756|Reactome:R-HSA-9013471 go-plus.json beta-mercaptopyruvate sulfurtransferase activity|mercaptopyruvate sulfurtransferase activity|3-mercaptopyruvate:cyanide sulfurtransferase activity|3-mercaptopyruvate sulphurtransferase activity http://purl.obolibrary.org/obo/GO_0016784 GO:0016780 biolink:MolecularActivity phosphotransferase activity, for other substituted phosphate groups Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor). EC:2.7.8.-|Reactome:R-HSA-163069|Reactome:R-HSA-162742 go-plus.json http://purl.obolibrary.org/obo/GO_0016780 GO:0002159 biolink:BiologicalProcess desmosome assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0002159 GO:0002155 biolink:BiologicalProcess regulation of thyroid hormone mediated signaling pathway Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway. go-plus.json regulation of thyroid hormone mediated signalling pathway http://purl.obolibrary.org/obo/GO_0002155 GO:0002156 biolink:BiologicalProcess negative regulation of thyroid hormone mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway. go-plus.json negative regulation of thyroid hormone mediated signalling pathway http://purl.obolibrary.org/obo/GO_0002156 GO:0002157 biolink:BiologicalProcess positive regulation of thyroid hormone mediated signaling pathway Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway. go-plus.json positive regulation of thyroid hormone mediated signalling pathway http://purl.obolibrary.org/obo/GO_0002157 GO:0002158 biolink:BiologicalProcess osteoclast proliferation The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0002158 GO:0002151 biolink:MolecularActivity G-quadruplex RNA binding Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad. go-plus.json G quartet RNA binding|G-quartet binding|G quartet binding|G quadruplex binding http://purl.obolibrary.org/obo/GO_0002151 GO:0002152 biolink:BiologicalProcess bile acid conjugation The process in which bile acids are covalently linked to taurine or glycine. go-plus.json http://purl.obolibrary.org/obo/GO_0002152 GO:0002153 biolink:MolecularActivity steroid receptor RNA activator RNA binding Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding. go-plus.json SRA binding http://purl.obolibrary.org/obo/GO_0002153 GO:0002154 biolink:BiologicalProcess thyroid hormone mediated signaling pathway A series of molecular signals mediated by the detection of a thyroid hormone. go-plus.json thyroid hormone mediated signalling pathway http://purl.obolibrary.org/obo/GO_0002154 GO:0002150 biolink:BiologicalProcess hypochlorous acid catabolic process The chemical reactions and pathways resulting in the breakdown of hypochlorous acid. go-plus.json HOCl catabolic process|hypochlorous acid catabolism|HClO catabolic process|hypochlorite catabolic process http://purl.obolibrary.org/obo/GO_0002150 CHEBI:90628 biolink:ChemicalSubstance benzyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_90628 chebi_ph7_3 GO:0016796 biolink:MolecularActivity exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. EC:3.1.15.- go-plus.json exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters http://purl.obolibrary.org/obo/GO_0016796 GO:0016797 biolink:MolecularActivity exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters. EC:3.1.16.- go-plus.json http://purl.obolibrary.org/obo/GO_0016797 GO:0016798 biolink:MolecularActivity hydrolase activity, acting on glycosyl bonds Catalysis of the hydrolysis of any glycosyl bond. EC:3.2.-.-|Reactome:R-HSA-2065233|Reactome:R-HSA-1793176 go-plus.json N-glycosylase|glycosylase|glycosidase activity http://purl.obolibrary.org/obo/GO_0016798 goslim_generic|goslim_chembl|goslim_yeast|goslim_drosophila GO:0016799 biolink:MolecularActivity hydrolase activity, hydrolyzing N-glycosyl compounds Catalysis of the hydrolysis of any N-glycosyl bond. EC:3.2.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016799 GO:0016792 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016792 GO:0016793 biolink:MolecularActivity triphosphoric monoester hydrolase activity Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group. Reactome:R-HSA-8866601|EC:3.1.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0016793 GO:0016794 biolink:MolecularActivity diphosphoric monoester hydrolase activity Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group. EC:3.1.7.- go-plus.json http://purl.obolibrary.org/obo/GO_0016794 GO:0016795 biolink:MolecularActivity phosphoric triester hydrolase activity Catalysis of the hydrolysis of a phosphoric triester. EC:3.1.8.- go-plus.json http://purl.obolibrary.org/obo/GO_0016795 GO:0016790 biolink:MolecularActivity thiolester hydrolase activity Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A. EC:3.1.2.- go-plus.json thiolesterase activity http://purl.obolibrary.org/obo/GO_0016790 GO:0016791 biolink:MolecularActivity phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. Reactome:R-HSA-9636457|MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN|Reactome:R-HSA-4419986|EC:3.1.3.- go-plus.json 4-nitrophenylphosphatase activity|phosphoric monoester hydrolase activity|p-nitrophenylphosphatase activity|ecto-p-nitrophenyl phosphatase activity|NPPase activity|para-nitrophenyl phosphatase activity|p-nitrophenylphosphate phosphohydrolase activity|phosphatase|4-nitrophenylphosphate phosphohydrolase activity|K-pNPPase activity|PNPPase activity|nitrophenyl phosphatase activity http://purl.obolibrary.org/obo/GO_0016791 goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_drosophila|goslim_aspergillus|goslim_metagenomics GO:0002126 biolink:BiologicalProcess instrumental aggressive behavior Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation. go-plus.json instrumental aggression http://purl.obolibrary.org/obo/GO_0002126 GO:0002127 biolink:BiologicalProcess tRNA wobble base cytosine methylation The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position. go-plus.json wobble position m5C biosynthesis http://purl.obolibrary.org/obo/GO_0002127 CHEBI:75017 biolink:ChemicalSubstance 1-lauroyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75017 chebi_ph7_3 GO:0002128 biolink:BiologicalProcess tRNA nucleoside ribose methylation The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position. go-plus.json http://purl.obolibrary.org/obo/GO_0002128 GO:0002129 biolink:BiologicalProcess wobble position guanine ribose methylation The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position. go-plus.json http://purl.obolibrary.org/obo/GO_0002129 CHEBI:75018 biolink:ChemicalSubstance 1-palmitoyl-2-lauroyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75018 chebi_ph7_3 GO:0002122 biolink:BiologicalProcess fear-induced aggressive behavior Aggressive behavior associated with attempts to flee from a threat. go-plus.json fear-induced aggression http://purl.obolibrary.org/obo/GO_0002122 GO:0002123 biolink:BiologicalProcess irritable aggressive behavior Aggressive behavior induced by frustration and directed against an available target. go-plus.json irritable aggression http://purl.obolibrary.org/obo/GO_0002123 GO:0002124 biolink:BiologicalProcess territorial aggressive behavior Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics. go-plus.json territorial aggression http://purl.obolibrary.org/obo/GO_0002124 GO:0002125 biolink:BiologicalProcess maternal aggressive behavior Aggressive behavior of a female to protect her offspring from a threat. go-plus.json maternal aggression http://purl.obolibrary.org/obo/GO_0002125 GO:0002120 biolink:BiologicalProcess obsolete predatory behavior OBSOLETE. Aggressive behavior involving attack on prey by a predator. go-plus.json predatory aggression|predatory aggressive behavior http://purl.obolibrary.org/obo/GO_0002120 GO:0002121 biolink:BiologicalProcess inter-male aggressive behavior Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious. go-plus.json inter-male aggression http://purl.obolibrary.org/obo/GO_0002121 GO:0016767 biolink:MolecularActivity geranylgeranyl-diphosphate geranylgeranyltransferase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate. EC:2.5.1.32|RHEA:22296|MetaCyc:2.5.1.32-RXN go-plus.json geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity|prephytoene-diphosphate synthase activity|phytoene synthetase activity|PSase activity http://purl.obolibrary.org/obo/GO_0016767 CHEBI:51080 biolink:ChemicalSubstance nitrate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_51080 GO:0016768 biolink:MolecularActivity spermine synthase activity Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine. MetaCyc:SPERMINE-SYNTHASE-RXN|EC:2.5.1.22|RHEA:19973|Reactome:R-HSA-351210 go-plus.json S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity|spermine synthetase activity|spermidine aminopropyltransferase activity http://purl.obolibrary.org/obo/GO_0016768 CHEBI:51081 biolink:ChemicalSubstance nitrates go-plus.json http://purl.obolibrary.org/obo/CHEBI_51081 GO:0016769 biolink:MolecularActivity transferase activity, transferring nitrogenous groups Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor). EC:2.6.-.- go-plus.json transferase activity, transferring other nitrogenous groups http://purl.obolibrary.org/obo/GO_0016769 GO:0016763 biolink:MolecularActivity pentosyltransferase activity Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). Reactome:R-HSA-112266|Reactome:R-HSA-112265|EC:2.4.2.- go-plus.json transferase activity, transferring pentosyl groups http://purl.obolibrary.org/obo/GO_0016763 GO:0016764 biolink:MolecularActivity obsolete transferase activity, transferring other glycosyl groups OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor). go-plus.json transferase activity, transferring other glycosyl groups http://purl.obolibrary.org/obo/GO_0016764 GO:0016765 biolink:MolecularActivity transferase activity, transferring alkyl or aryl (other than methyl) groups Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). Reactome:R-HSA-4419978|Reactome:R-HSA-4755545|EC:2.5.1.-|Reactome:R-HSA-6782893 go-plus.json transferase activity, transferring alkyl or aryl groups, other than methyl groups http://purl.obolibrary.org/obo/GO_0016765 goslim_chembl|goslim_drosophila|goslim_generic GO:0016766 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016766 GO:0016760 biolink:MolecularActivity cellulose synthase (UDP-forming) activity Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1). RHEA:19929|EC:2.4.1.12|MetaCyc:CELLULOSE-SYNTHASE-UDP-FORMING-RXN go-plus.json UDP-glucose-beta-D-glucan glucosyltransferase activity|beta-glucan synthase activity|UDPglucose-beta-glucan glucosyltransferase activity|UDP-glucose-cellulose glucosyltransferase activity|UDP-glucose-1,4-beta-glucan glucosyltransferase activity|1,4-beta-D-glucan synthase activity|UDPglucose-cellulose glucosyltransferase activity|beta-1,4-glucan synthase activity|GS-I|uridine diphosphoglucose-cellulose glucosyltransferase activity|uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity|UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|beta-1,4-glucosyltransferase activity|1,4-beta-glucan synthase activity|UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|beta-1,4-glucan synthetase activity|glucan synthase activity http://purl.obolibrary.org/obo/GO_0016760 GO:0016761 biolink:MolecularActivity cellulose synthase (GDP-forming) activity Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1). RHEA:17797|MetaCyc:CELLULOSE-SYNTHASE-GDP-FORMING-RXN|EC:2.4.1.29 go-plus.json cellulose synthase (guanosine diphosphate-forming) activity|GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|GDP-glucose-beta-D-glucan glucosyltransferase activity|GDP-glucose-cellulose glucosyltransferase activity|guanosine diphosphoglucose-cellulose glucosyltransferase activity|guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0016761 GO:0016762 biolink:MolecularActivity xyloglucan:xyloglucosyl transferase activity Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan. MetaCyc:2.4.1.207-RXN|EC:2.4.1.207 go-plus.json endoxyloglucan transferase activity|xyloglucan:xyloglucan xyloglucanotransferase activity|endo-xyloglucan transferase activity|xyloglucan endotransglucosylase activity http://purl.obolibrary.org/obo/GO_0016762 CHEBI:51086 biolink:ChemicalSubstance chemical role go-plus.json http://purl.obolibrary.org/obo/CHEBI_51086 GO:0002137 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002137 GO:0002138 biolink:BiologicalProcess retinoic acid biosynthetic process The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A. go-plus.json retinoic acid anabolic process http://purl.obolibrary.org/obo/GO_0002138 GO:0002139 biolink:CellularComponent stereocilia coupling link A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle. go-plus.json http://purl.obolibrary.org/obo/GO_0002139 CHEBI:75028 biolink:ChemicalSubstance 1-(alpha,beta-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_75028 chebi_ph7_3 CHEBI:75029 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75029 chebi_ph7_3 GO:0002133 biolink:CellularComponent polycystin complex A stable heterodimeric complex composed of polycystin-1 and polycystin-2. go-plus.json http://purl.obolibrary.org/obo/GO_0002133 GO:0002134 biolink:MolecularActivity UTP binding Binding to UTP, uridine 5'-triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0002134 CHEBI:145217 biolink:ChemicalSubstance epoxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145217 GO:0002135 biolink:MolecularActivity CTP binding Binding to CTP, cytidine 5'-triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0002135 GO:0002136 biolink:BiologicalProcess tRNA wobble base lysidine biosynthesis The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine. go-plus.json http://purl.obolibrary.org/obo/GO_0002136 GO:0002130 biolink:BiologicalProcess wobble position ribose methylation The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position. go-plus.json http://purl.obolibrary.org/obo/GO_0002130 GO:0002131 biolink:BiologicalProcess wobble position cytosine ribose methylation The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position. go-plus.json http://purl.obolibrary.org/obo/GO_0002131 GO:0002132 biolink:BiologicalProcess wobble position uridine ribose methylation The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position. go-plus.json http://purl.obolibrary.org/obo/GO_0002132 CHEBI:89656 biolink:ChemicalSubstance Leu-enkephalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_89656 GO:0016778 biolink:MolecularActivity diphosphotransferase activity Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor). EC:2.7.6.- go-plus.json http://purl.obolibrary.org/obo/GO_0016778 GO:0016779 biolink:MolecularActivity nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group to a reactant. Reactome:R-HSA-6782434|EC:2.7.7.- go-plus.json http://purl.obolibrary.org/obo/GO_0016779 goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida GO:0016774 biolink:MolecularActivity phosphotransferase activity, carboxyl group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor). EC:2.7.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016774 GO:0016775 biolink:MolecularActivity phosphotransferase activity, nitrogenous group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor). EC:2.7.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016775 GO:0016776 biolink:MolecularActivity phosphotransferase activity, phosphate group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor). EC:2.7.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0016776 GO:0016777 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016777 GO:0016770 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016770 CHEBI:75023 biolink:ChemicalSubstance Ins-1-P-6-Man-1-6-Ins-1-P-Cer C(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75023 chebi_ph7_3 GO:0016771 biolink:MolecularActivity obsolete transferase activity, transferring other nitrogenous groups OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor). go-plus.json transferase activity, transferring other nitrogenous groups http://purl.obolibrary.org/obo/GO_0016771 CHEBI:51078 biolink:ChemicalSubstance 13-sophorosyloxydocosanoate 6',6''-diacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_51078 CHEBI:75020 biolink:ChemicalSubstance 1-palmitoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_75020 chebi_ph7_3 GO:0016772 biolink:MolecularActivity transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). EC:2.7.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016772 goslim_chembl GO:0016773 biolink:MolecularActivity phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). EC:2.7.1.-|Reactome:R-HSA-2161193 go-plus.json http://purl.obolibrary.org/obo/GO_0016773 goslim_drosophila CHEBI:75026 biolink:ChemicalSubstance 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_75026 chebi_ph7_3 CHEBI:51075 biolink:ChemicalSubstance sophorolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_51075 GO:1905490 biolink:BiologicalProcess negative regulation of sensory neuron axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance. go-plus.json down-regulation of sensory neuron axon guidance|downregulation of sensory neuron axon guidance|down regulation of sensory neuron axon guidance|inhibition of sensory neuron axon guidance http://purl.obolibrary.org/obo/GO_1905490 GO:1905491 biolink:BiologicalProcess positive regulation of sensory neuron axon guidance Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance. go-plus.json up regulation of sensory neuron axon guidance|upregulation of sensory neuron axon guidance|up-regulation of sensory neuron axon guidance|activation of sensory neuron axon guidance http://purl.obolibrary.org/obo/GO_1905491 GO:1905492 biolink:BiologicalProcess positive regulation of branching morphogenesis of a nerve Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. go-plus.json upregulation of branching morphogenesis of a nerve|up-regulation of branching morphogenesis of a nerve|activation of branching morphogenesis of a nerve|up regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_1905492 GO:1905493 biolink:BiologicalProcess regulation of G-quadruplex DNA binding Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding. go-plus.json regulation of G-quartet DNA binding|regulation of G-quartet binding|regulation of tetraplex DNA binding|regulation of quadruplex DNA binding|regulation of G-DNA binding|regulation of G quadruplex DNA binding|regulation of G quartet DNA binding|regulation of G quartet binding http://purl.obolibrary.org/obo/GO_1905493 GO:1905494 biolink:BiologicalProcess negative regulation of G-quadruplex DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding. go-plus.json down-regulation of G-quadruplex DNA binding|inhibition of tetraplex DNA binding|negative regulation of G-DNA binding|down-regulation of G-DNA binding|negative regulation of G quartet DNA binding|negative regulation of quadruplex DNA binding|down-regulation of G quartet DNA binding|down regulation of G-quartet DNA binding|down-regulation of quadruplex DNA binding|inhibition of G-DNA binding|downregulation of G-quadruplex DNA binding|downregulation of G-quartet DNA binding|down regulation of G-quadruplex DNA binding|down-regulation of G quadruplex DNA binding|inhibition of G quartet DNA binding|down regulation of tetraplex DNA binding|negative regulation of G quadruplex DNA binding|inhibition of G-quadruplex DNA binding|downregulation of quadruplex DNA binding|downregulation of tetraplex DNA binding|down-regulation of G-quartet DNA binding|negative regulation of G-quartet DNA binding|down regulation of quadruplex DNA binding|down regulation of G-DNA binding|inhibition of quadruplex DNA binding|downregulation of G quadruplex DNA binding|downregulation of G-DNA binding|down regulation of G quartet DNA binding|inhibition of G-quartet DNA binding|negative regulation of tetraplex DNA binding|down regulation of G quadruplex DNA binding|down-regulation of tetraplex DNA binding|inhibition of G quadruplex DNA binding|downregulation of G quartet DNA binding http://purl.obolibrary.org/obo/GO_1905494 GO:1905495 biolink:BiologicalProcess positive regulation of G-quadruplex DNA binding Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding. go-plus.json activation of quadruplex DNA binding|up-regulation of quadruplex DNA binding|up regulation of G quartet DNA binding|up-regulation of tetraplex DNA binding|activation of G quartet DNA binding|positive regulation of G quartet DNA binding|upregulation of G-quartet DNA binding|up regulation of G-quadruplex DNA binding|up-regulation of G quadruplex DNA binding|activation of G quadruplex DNA binding|up-regulation of G-DNA binding|positive regulation of quadruplex DNA binding|upregulation of tetraplex DNA binding|up regulation of quadruplex DNA binding|up-regulation of G quartet DNA binding|up regulation of G-quartet DNA binding|activation of G-quartet DNA binding|positive regulation of G-quartet DNA binding|upregulation of G-quadruplex DNA binding|upregulation of G-DNA binding|positive regulation of G quadruplex DNA binding|up regulation of G quadruplex DNA binding|up regulation of tetraplex DNA binding|activation of tetraplex DNA binding|positive regulation of tetraplex DNA binding|upregulation of quadruplex DNA binding|upregulation of G quartet DNA binding|up-regulation of G-quadruplex DNA binding|activation of G-quadruplex DNA binding|up-regulation of G-quartet DNA binding|up regulation of G-DNA binding|activation of G-DNA binding|positive regulation of G-DNA binding|upregulation of G quadruplex DNA binding http://purl.obolibrary.org/obo/GO_1905495 GO:1905496 biolink:BiologicalProcess regulation of triplex DNA binding Any process that modulates the frequency, rate or extent of triplex DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_1905496 GO:1905497 biolink:BiologicalProcess negative regulation of triplex DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding. go-plus.json down-regulation of triplex DNA binding|inhibition of triplex DNA binding|down regulation of triplex DNA binding|downregulation of triplex DNA binding http://purl.obolibrary.org/obo/GO_1905497 CHEBI:16618 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16618 CHEBI:16619 biolink:ChemicalSubstance (2-trans,6-trans)-farnesol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16619 chebi_ph7_3 GO:1905498 biolink:BiologicalProcess positive regulation of triplex DNA binding Any process that activates or increases the frequency, rate or extent of triplex DNA binding. go-plus.json up-regulation of triplex DNA binding|upregulation of triplex DNA binding|up regulation of triplex DNA binding|activation of triplex DNA binding http://purl.obolibrary.org/obo/GO_1905498 GO:1905488 biolink:BiologicalProcess positive regulation of anterior/posterior axon guidance Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance. go-plus.json up-regulation of anterior/posterior axon pathfinding|positive regulation of anterior-posterior axon guidance|upregulation of anterior/posterior axon pathfinding|up regulation of anterior-posterior axon guidance|up regulation of anterior/posterior axon guidance|upregulation of anterior-posterior axon guidance|up regulation of anterior/posterior axon pathfinding|activation of anterior/posterior axon pathfinding|upregulation of anterior/posterior axon guidance|positive regulation of anterior/posterior axon pathfinding|up-regulation of anterior-posterior axon guidance|activation of anterior-posterior axon guidance|up-regulation of anterior/posterior axon guidance|activation of anterior/posterior axon guidance http://purl.obolibrary.org/obo/GO_1905488 CHEBI:16616 biolink:ChemicalSubstance 2-methylpropanal O-methyloxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_16616 chebi_ph7_3 CHEBI:16617 biolink:ChemicalSubstance 1-acylglycerophosphoinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16617 GO:1905489 biolink:BiologicalProcess regulation of sensory neuron axon guidance Any process that modulates the frequency, rate or extent of sensory neuron axon guidance. go-plus.json http://purl.obolibrary.org/obo/GO_1905489 CHEBI:16615 biolink:ChemicalSubstance biotin amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16615 chebi_ph7_3 GO:0075280 biolink:BiologicalProcess regulation of uredinium development Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075280 CHEBI:16613 biolink:ChemicalSubstance glutathionylspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16613 GO:0075281 biolink:BiologicalProcess positive regulation of uredinium development Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075281 CHEBI:16610 biolink:ChemicalSubstance spermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16610 GO:0075282 biolink:BiologicalProcess negative regulation of uredinium development Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075282 GO:0075283 biolink:BiologicalProcess sporulation resulting in formation of a multicellular or syncytial spore The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure. go-plus.json multicellular or syncytial spore formation by sporulation http://purl.obolibrary.org/obo/GO_0075283 GO:0075284 biolink:BiologicalProcess asexual sporulation resulting in formation of a multicellular or syncytial spore The formation of a multicellular or syncytial spore via septations derived from mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0075284 GO:0075285 biolink:BiologicalProcess sexual sporulation resulting in formation of a multicellular or syncytial spore The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0075285 GO:0075286 biolink:BiologicalProcess regulation of sporangiospore formation Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0075286 GO:0075287 biolink:BiologicalProcess positive regulation of sporangiospore formation Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0075287 GO:0075288 biolink:BiologicalProcess negative regulation of sporangiospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0075288 GO:0075289 biolink:BiologicalProcess aplanospore formation The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. go-plus.json http://purl.obolibrary.org/obo/GO_0075289 CHEBI:16609 biolink:ChemicalSubstance 2-dehydro-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16609 chebi_ph7_3 CHEBI:16607 biolink:ChemicalSubstance 4-aminoimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16607 chebi_ph7_3 CHEBI:16608 biolink:ChemicalSubstance 5alpha-cholest-8-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16608 chebi_ph7_3 CHEBI:16605 biolink:ChemicalSubstance allyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16605 chebi_ph7_3 GO:1905499 biolink:BiologicalProcess trichome papilla formation The aggregation, arrangement and bonding together of a set of components to form a trichome papilla. go-plus.json trichome papilla assembly http://purl.obolibrary.org/obo/GO_1905499 CHEBI:16606 biolink:ChemicalSubstance N-benzoyl-4-hydroxyanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16606 CHEBI:16603 biolink:ChemicalSubstance DIMBOA glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16603 chebi_ph7_3 CHEBI:16602 biolink:ChemicalSubstance trichloroethene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16602 chebi_ph7_3 GO:0075270 biolink:BiologicalProcess negative regulation of aecium development Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075270 GO:0075271 biolink:BiologicalProcess zygosporangium development The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075271 CHEBI:16600 biolink:ChemicalSubstance mesaconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16600 GO:0075272 biolink:BiologicalProcess regulation of zygosporangium development Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075272 GO:0075273 biolink:BiologicalProcess positive regulation of zygosporangium development Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075273 GO:0075274 biolink:BiologicalProcess negative regulation of zygosporangium development Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075274 GO:0075275 biolink:BiologicalProcess telium development The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075275 GO:0075276 biolink:BiologicalProcess regulation of telium development Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075276 GO:0075277 biolink:BiologicalProcess positive regulation of telium development Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075277 GO:0075278 biolink:BiologicalProcess negative regulation of telium development Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075278 GO:0075279 biolink:BiologicalProcess uredinium development The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. go-plus.json development of uredium http://purl.obolibrary.org/obo/GO_0075279 GO:2000805 biolink:BiologicalProcess negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. go-plus.json negative regulation of transcription termination from Pol II promoter, poly(A) coupled|negative regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|negative regulation of termination of RNA polymerase II transcription, polyadenylation-coupled http://purl.obolibrary.org/obo/GO_2000805 GO:2000806 biolink:BiologicalProcess positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. go-plus.json positive regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|positive regulation of termination of RNA polymerase II transcription, polyadenylation-coupled|positive regulation of transcription termination from Pol II promoter, poly(A) coupled http://purl.obolibrary.org/obo/GO_2000806 GO:2000807 biolink:BiologicalProcess regulation of synaptic vesicle clustering Any process that modulates the frequency, rate or extent of synaptic vesicle clustering. go-plus.json http://purl.obolibrary.org/obo/GO_2000807 GO:2000808 biolink:BiologicalProcess negative regulation of synaptic vesicle clustering Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering. go-plus.json http://purl.obolibrary.org/obo/GO_2000808 GO:2000809 biolink:BiologicalProcess positive regulation of synaptic vesicle clustering Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering. go-plus.json http://purl.obolibrary.org/obo/GO_2000809 GO:2000800 biolink:BiologicalProcess regulation of endocardial cushion to mesenchymal transition involved in heart valve formation Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. go-plus.json regulation of endocardial cushion to mesenchymal transition involved in valve formation http://purl.obolibrary.org/obo/GO_2000800 GO:2000801 biolink:BiologicalProcess negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. go-plus.json negative regulation of endocardial cushion to mesenchymal transition involved in valve formation http://purl.obolibrary.org/obo/GO_2000801 GO:2000802 biolink:BiologicalProcess positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. go-plus.json positive regulation of endocardial cushion to mesenchymal transition involved in valve formation http://purl.obolibrary.org/obo/GO_2000802 GO:2000803 biolink:BiologicalProcess endosomal signal transduction The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction. go-plus.json endosome-based signaling|signalling cascade in endosome|signaling cascade in endosome|signalling pathway in endosome|signaling from endosome|signaling pathway in endosome http://purl.obolibrary.org/obo/GO_2000803 GO:2000804 biolink:BiologicalProcess regulation of termination of RNA polymerase II transcription, poly(A)-coupled Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. go-plus.json regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|regulation of termination of RNA polymerase II transcription, polyadenylation-coupled|regulation of transcription termination from Pol II promoter, poly(A) coupled http://purl.obolibrary.org/obo/GO_2000804 CHEBI:16638 biolink:ChemicalSubstance 3-methylbutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_16638 chebi_ph7_3 CHEBI:16639 biolink:ChemicalSubstance 4-methoxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16639 chebi_ph7_3 CHEBI:16634 biolink:ChemicalSubstance raffinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16634 chebi_ph7_3 CHEBI:16635 biolink:ChemicalSubstance Met-tRNA(Met) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16635 CHEBI:16632 biolink:ChemicalSubstance vanillate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16632 chebi_ph7_3 CHEBI:16633 biolink:ChemicalSubstance L-selenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16633 CHEBI:16630 biolink:ChemicalSubstance 3-dehydroshikimate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16630 chebi_ph7_3 CHEBI:16631 biolink:ChemicalSubstance vitexin 2''-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16631 GO:2000816 biolink:BiologicalProcess negative regulation of mitotic sister chromatid separation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation. go-plus.json negative regulation of mitotic sister chromatid resolution|negative regulation of mitotic chromosome separation|negative regulation of sister chromatid separation during mitosis|negative regulation of chromosome separation during mitosis http://purl.obolibrary.org/obo/GO_2000816 GO:2000817 biolink:BiologicalProcess regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore Any regulation of histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore. go-plus.json regulation of histone H3-T3 phosphorylation involved in chromosomal passenger complex localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localisation to kinetochore|regulation of histone H3-T3 phosphorylation involved in CPC localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in CPC complex localization to kinetochore http://purl.obolibrary.org/obo/GO_2000817 GO:2000818 biolink:BiologicalProcess negative regulation of myoblast proliferation Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000818 GO:2000819 biolink:BiologicalProcess regulation of nucleotide-excision repair Any process that modulates the frequency, rate or extent of nucleotide-excision repair. go-plus.json regulation of NER|regulation of pyrimidine-dimer repair, DNA damage excision|regulation of interstrand crosslink repair|regulation of intrastrand cross-link repair http://purl.obolibrary.org/obo/GO_2000819 GO:0099243 biolink:CellularComponent extrinsic component of synaptic membrane The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0099243 goslim_synapse GO:0099240 biolink:CellularComponent intrinsic component of synaptic membrane The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to synaptic membrane http://purl.obolibrary.org/obo/GO_0099240 goslim_synapse GO:2000810 biolink:BiologicalProcess regulation of bicellular tight junction assembly Any process that modulates the frequency, rate or extent of tight junction assembly. go-plus.json regulation of tight junction formation http://purl.obolibrary.org/obo/GO_2000810 GO:2000811 biolink:BiologicalProcess negative regulation of anoikis Any process that stops, prevents or reduces the frequency, rate or extent of anoikis. go-plus.json negative regulation of detachment induced cell death|negative regulation of suspension induced apoptosis http://purl.obolibrary.org/obo/GO_2000811 GO:2000812 biolink:BiologicalProcess regulation of barbed-end actin filament capping Any process that modulates the frequency, rate or extent of barbed-end actin filament capping. go-plus.json regulation of barbed-end F-actin capping activity|regulation of plus-end actin filament capping activity|regulation of barbed-end actin capping activity|regulation of plus-end F-actin capping activity http://purl.obolibrary.org/obo/GO_2000812 GO:2000813 biolink:BiologicalProcess negative regulation of barbed-end actin filament capping Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping. go-plus.json negative regulation of barbed-end F-actin capping activity|negative regulation of barbed-end actin capping activity|negative regulation of plus-end F-actin capping activity|negative regulation of plus-end actin filament capping activity http://purl.obolibrary.org/obo/GO_2000813 GO:2000814 biolink:BiologicalProcess positive regulation of barbed-end actin filament capping Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping. go-plus.json positive regulation of barbed-end F-actin capping activity|positive regulation of barbed-end actin capping activity|positive regulation of plus-end F-actin capping activity|positive regulation of plus-end actin filament capping activity http://purl.obolibrary.org/obo/GO_2000814 CHEBI:16629 biolink:ChemicalSubstance 4-amino-2-methyl-5-diphosphooxymethylpyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16629 GO:2000815 biolink:BiologicalProcess regulation of mRNA stability involved in response to oxidative stress A process of regulation of mRNA stability that is involved in a response to oxidative stress. go-plus.json http://purl.obolibrary.org/obo/GO_2000815 CHEBI:16628 biolink:ChemicalSubstance methylguanidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16628 CHEBI:16625 biolink:ChemicalSubstance methylmalonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_16625 GO:0075290 biolink:BiologicalProcess regulation of aplanospore formation Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. go-plus.json http://purl.obolibrary.org/obo/GO_0075290 GO:0075291 biolink:BiologicalProcess positive regulation of aplanospore formation Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. go-plus.json http://purl.obolibrary.org/obo/GO_0075291 CHEBI:16624 biolink:ChemicalSubstance Leu-tRNA(Leu) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16624 CHEBI:16621 biolink:ChemicalSubstance N-phosphotaurocyamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16621 GO:0075292 biolink:BiologicalProcess negative regulation of aplanospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. go-plus.json http://purl.obolibrary.org/obo/GO_0075292 CHEBI:16622 biolink:ChemicalSubstance 3-dehydro-2-deoxy-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16622 GO:0075293 biolink:BiologicalProcess response to host pH environment Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response of symbiont to host pH environment http://purl.obolibrary.org/obo/GO_0075293 GO:0075294 biolink:BiologicalProcess positive regulation by symbiont of entry into host Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. go-plus.json positive regulation by organism of entry into other organism involved in symbiotic interaction|up regulation by symbiont of entry into host|upregulation by organism of entry into other organism during symbiotic interaction|activation by symbiont of entry into host|activation by organism of entry into other organism during symbiotic interaction|up-regulation by organism of entry into other organism during symbiotic interaction|up-regulation by symbiont of entry into host|positive regulation by organism of entry into other organism during symbiotic interaction|upregulation by symbiont of entry into host|up regulation by organism of entry into other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0075294 GO:0075295 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075295 CHEBI:16620 biolink:ChemicalSubstance dTDP-4-dehydro-6-deoxy-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16620 GO:0075296 biolink:BiologicalProcess positive regulation of ascospore formation Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. go-plus.json http://purl.obolibrary.org/obo/GO_0075296 GO:0075297 biolink:BiologicalProcess negative regulation of ascospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. go-plus.json http://purl.obolibrary.org/obo/GO_0075297 GO:0075298 biolink:BiologicalProcess regulation of zygospore formation Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0075298 GO:0075299 biolink:BiologicalProcess positive regulation of zygospore formation Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0075299 NCBITaxon:28890 biolink:OrganismalEntity Euryarchaeota go-plus.json Methanobacteriota|Methanobacteraeota|euryarchaeotes http://purl.obolibrary.org/obo/NCBITaxon_28890 NCBITaxon:28889 biolink:OrganismalEntity Crenarchaeota go-plus.json Eocyta|eocytes|crenarchaeotes|Thermoproteota|Thermoproteaeota http://purl.obolibrary.org/obo/NCBITaxon_28889 GO:0075203 biolink:BiologicalProcess positive regulation of penetration hypha formation Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont penetration hypha formation for entry into host http://purl.obolibrary.org/obo/GO_0075203 GO:0051236 biolink:BiologicalProcess establishment of RNA localization The directed movement of RNA to a specific location. go-plus.json RNA recruitment|RNA positioning|establishment of RNA localisation http://purl.obolibrary.org/obo/GO_0051236 GO:0075204 biolink:BiologicalProcess obsolete negative regulation of symbiont penetration hypha formation for entry into host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075204 GO:0051237 biolink:BiologicalProcess maintenance of RNA location Any process in which RNA is maintained in a location and prevented from moving elsewhere. go-plus.json RNA retention|maintenance of RNA localization http://purl.obolibrary.org/obo/GO_0051237 GO:0051234 biolink:BiologicalProcess establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. go-plus.json establishment of localisation http://purl.obolibrary.org/obo/GO_0051234 goslim_pir|goslim_flybase_ribbon|goslim_mouse|goslim_agr GO:0075205 biolink:BiologicalProcess obsolete modulation by host of symbiont cAMP-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The cAMP-mediated signal transduction is defined as a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by host of symbiont cAMP-mediated signaling|modulation by host of symbiont cAMP-mediated signalling|regulation by host of symbiont cAMP-mediated signaling http://purl.obolibrary.org/obo/GO_0075205 GO:0075206 biolink:BiologicalProcess obsolete positive regulation by host of symbiont cAMP-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by host of symbiont cAMP-mediated signaling http://purl.obolibrary.org/obo/GO_0075206 GO:0051235 biolink:BiologicalProcess maintenance of location Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. go-plus.json retention|storage|maintenance of localization|sequestering http://purl.obolibrary.org/obo/GO_0051235 GO:0075207 biolink:BiologicalProcess obsolete negative regulation by host of symbiont cAMP-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by host of symbiont cAMP-mediated signaling http://purl.obolibrary.org/obo/GO_0075207 GO:0075208 biolink:BiologicalProcess modulation by symbiont of host cAMP-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host cAMP-mediated signaling http://purl.obolibrary.org/obo/GO_0075208 GO:0051238 biolink:BiologicalProcess sequestering of metal ion The process of binding or confining metal ions such that they are separated from other components of a biological system. go-plus.json retention of metal ion|metal ion sequestration|metal ion sequestering|sequestration of metal ion|metal ion retention|storage of metal ion|metal ion storage http://purl.obolibrary.org/obo/GO_0051238 GO:0075209 biolink:BiologicalProcess induction by symbiont of host cAMP-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host cAMP-mediated signaling|positive regulation by symbiont of host cAMP-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075209 GO:0051239 biolink:BiologicalProcess regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. go-plus.json http://purl.obolibrary.org/obo/GO_0051239 GO:2000863 biolink:BiologicalProcess positive regulation of estrogen secretion Any process that activates or increases the frequency, rate or extent of estrogen secretion. go-plus.json positive regulation of oestrogen secretion http://purl.obolibrary.org/obo/GO_2000863 GO:0016907 biolink:MolecularActivity G protein-coupled acetylcholine receptor activity Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G protein coupled acetylcholine receptor activity|metabotropic acetylcholine receptor activity|muscarinic acetylcholine receptor activity|acetylcholine receptor activity, G-protein coupled|G-protein coupled acetylcholine receptor activity http://purl.obolibrary.org/obo/GO_0016907 GO:2000864 biolink:BiologicalProcess regulation of estradiol secretion Any process that modulates the frequency, rate or extent of estradiol secretion. go-plus.json regulation of oestradiol secretion http://purl.obolibrary.org/obo/GO_2000864 GO:0016908 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016908 GO:2000865 biolink:BiologicalProcess negative regulation of estradiol secretion Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion. go-plus.json negative regulation of oestradiol secretion http://purl.obolibrary.org/obo/GO_2000865 GO:0016909 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016909 GO:2000866 biolink:BiologicalProcess positive regulation of estradiol secretion Any process that activates or increases the frequency, rate or extent of estradiol secretion. go-plus.json positive regulation of oestradiol secretion http://purl.obolibrary.org/obo/GO_2000866 GO:2000867 biolink:BiologicalProcess regulation of estrone secretion Any process that modulates the frequency, rate or extent of estrone secretion. go-plus.json regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion|regulation of folliculin secretion http://purl.obolibrary.org/obo/GO_2000867 GO:0016903 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.2.-.- go-plus.json oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016903 GO:2000868 biolink:BiologicalProcess negative regulation of estrone secretion Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion. go-plus.json negative regulation of folliculin secretion|negative regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion http://purl.obolibrary.org/obo/GO_2000868 GO:0016904 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016904 GO:2000869 biolink:BiologicalProcess positive regulation of estrone secretion Any process that activates or increases the frequency, rate or extent of estrone secretion. go-plus.json positive regulation of folliculin secretion|positive regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion http://purl.obolibrary.org/obo/GO_2000869 CHEBI:26020 biolink:ChemicalSubstance phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26020 GO:0016905 biolink:MolecularActivity myosin heavy chain kinase activity Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate. EC:2.7.11.7|RHEA:11424 go-plus.json ATP:myosin heavy-chain O-phosphotransferase activity|myosin I heavy-chain kinase activity|myosin-heavy-chain kinase activity|STK6|myosin II heavy chain kinase activity|myosin heavy chain kinase A activity|calmodulin-dependent myosin heavy chain kinase activity|ATP:myosin-heavy-chain O-phosphotransferase activity|MHCK|MIHC kinase activity|myosin I heavy chain kinase activity|myosin heavy-chain kinase activity|myosin II heavy-chain kinase activity http://purl.obolibrary.org/obo/GO_0016905 GO:0016906 biolink:MolecularActivity sterol 3-beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol. MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.173|RHEA:22724 go-plus.json UDP-glucose-sterol glucosyltransferase activity|UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity|sterol glucosyltransferase activity|sterol-beta-D-glucosyltransferase activity|UDPG-SGTase activity|sterol 3beta-glucosyltransferase activity|sterol:UDPG glucosyltransferase activity|uridine diphosphoglucose-sterol glucosyltransferase activity|uridine diphosphoglucose-poriferasterol glucosyltransferase activity|UDP-glucose-sterol beta-glucosyltransferase activity|UDPG:sterol glucosyltransferase activity|UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity|UDP-glucose:sterol glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0016906 GO:1905410 biolink:BiologicalProcess regulation of mitotic cohesin unloading Any process that modulates the frequency, rate or extent of mitotic cohesin unloading. go-plus.json http://purl.obolibrary.org/obo/GO_1905410 GO:1905400 biolink:BiologicalProcess negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. go-plus.json downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T-cell apoptosis|inhibition of activated CD4-positive, alpha-beta T-cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T cell apoptosis|downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD4-positive, alpha-beta T cell apoptosis|inhibition of activated CD4-positive, alpha-beta T cell apoptotic process|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptosis|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T cell apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process http://purl.obolibrary.org/obo/GO_1905400 GO:1905401 biolink:BiologicalProcess positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. go-plus.json upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD4-positive, alpha-beta T cell apoptosis|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T cell apoptosis|activation of activated CD4-positive, alpha-beta T cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T-cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T cell apoptosis|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_1905401 GO:0016900 biolink:MolecularActivity oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule. EC:1.1.4.- go-plus.json oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor http://purl.obolibrary.org/obo/GO_0016900 GO:0016901 biolink:MolecularActivity oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. EC:1.1.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0016901 GO:1905402 biolink:BiologicalProcess regulation of activated CD8-positive, alpha-beta T cell apoptotic process Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. go-plus.json regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|regulation of activated CD8-positive, alpha-beta T-cell apoptosis|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|regulation of activated CD8-positive, alpha-beta T cell apoptosis|regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_1905402 GO:1905403 biolink:BiologicalProcess negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. go-plus.json negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T-cell apoptosis|inhibition of activated CD8-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T cell apoptosis|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T-cell apoptosis|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T cell apoptosis|inhibition of activated CD8-positive, alpha-beta T cell apoptotic process|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T-cell apoptosis|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down regulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_1905403 GO:0016902 biolink:MolecularActivity obsolete oxidoreductase activity, acting on the CH-OH group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound. go-plus.json oxidoreductase activity, acting on the CH-OH group of donors, other acceptors http://purl.obolibrary.org/obo/GO_0016902 GO:1905404 biolink:BiologicalProcess positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. go-plus.json positive regulation of activated CD8-positive, alpha-beta T cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T cell apoptosis|activation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-cell apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD8-positive, alpha-beta T-cell apoptosis|upregulation of activated CD8-positive, alpha-beta T cell apoptosis|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T-cell apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T cell apoptotic process|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-cell apoptosis http://purl.obolibrary.org/obo/GO_1905404 GO:2000860 biolink:BiologicalProcess positive regulation of aldosterone secretion Any process that activates or increases the frequency, rate or extent of aldosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000860 GO:1905405 biolink:BiologicalProcess regulation of mitotic cohesin loading Any process that modulates the frequency, rate or extent of mitotic cohesin loading. go-plus.json http://purl.obolibrary.org/obo/GO_1905405 GO:2000861 biolink:BiologicalProcess regulation of estrogen secretion Any process that modulates the frequency, rate or extent of estrogen secretion. go-plus.json regulation of oestrogen secretion http://purl.obolibrary.org/obo/GO_2000861 CHEBI:16698 biolink:ChemicalSubstance cyanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16698 chebi_ph7_3 GO:1905406 biolink:BiologicalProcess positive regulation of mitotic cohesin loading Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading. go-plus.json http://purl.obolibrary.org/obo/GO_1905406 GO:1905407 biolink:BiologicalProcess regulation of creatine transmembrane transporter activity Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905407 GO:2000862 biolink:BiologicalProcess negative regulation of estrogen secretion Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion. go-plus.json negative regulation of oestrogen secretion http://purl.obolibrary.org/obo/GO_2000862 CHEBI:16699 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-arabinonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16699 chebi_ph7_3 GO:1905408 biolink:BiologicalProcess negative regulation of creatine transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity. go-plus.json down regulation of creatine transmembrane transporter activity|downregulation of creatine transmembrane transporter activity|down-regulation of creatine transmembrane transporter activity|inhibition of creatine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1905408 CHEBI:16696 biolink:ChemicalSubstance 3-methylthiopropylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16696 GO:1905409 biolink:BiologicalProcess positive regulation of creatine transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity. go-plus.json upregulation of creatine transmembrane transporter activity|up regulation of creatine transmembrane transporter activity|activation of creatine transmembrane transporter activity|up-regulation of creatine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1905409 CHEBI:16697 biolink:ChemicalSubstance indan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16697 chebi_ph7_3 CHEBI:16694 biolink:ChemicalSubstance 5D-(5/6)-2,6-dihydroxy-5-(hydroxymethyl)cyclohex-2-en-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16694 chebi_ph7_3 CHEBI:16695 biolink:ChemicalSubstance uridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16695 GO:0051232 biolink:BiologicalProcess meiotic spindle elongation The lengthening of the distance between poles of the spindle during a meiotic cell cycle. go-plus.json spindle elongation during meiosis http://purl.obolibrary.org/obo/GO_0051232 CHEBI:16692 biolink:ChemicalSubstance diphthamide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_16692 chebi_ph7_3 GO:0051233 biolink:CellularComponent spindle midzone The area in the center of the spindle where the spindle microtubules from opposite poles overlap. go-plus.json central spindle|spindle equator http://purl.obolibrary.org/obo/GO_0051233 GO:0075200 biolink:BiologicalProcess obsolete negative regulation of symbiont haustorium neck formation for entry into host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075200 CHEBI:16693 biolink:ChemicalSubstance ADP-D-glycero-D-manno-heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16693 GO:0075201 biolink:BiologicalProcess penetration hypha formation The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation of symbiont penetration hypha for entry into host|symbiont penetration hypha formation for entry into host http://purl.obolibrary.org/obo/GO_0075201 GO:0051230 biolink:BiologicalProcess spindle disassembly The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. go-plus.json spindle degradation|spindle breakdown|spindle catabolism http://purl.obolibrary.org/obo/GO_0051230 CHEBI:16690 biolink:ChemicalSubstance guanosine 3'-diphosphate 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16690 GO:0075202 biolink:BiologicalProcess regulation of penetration hypha formation Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of symbiont penetration hypha formation for entry into host http://purl.obolibrary.org/obo/GO_0075202 GO:0051231 biolink:BiologicalProcess spindle elongation The cell cycle process in which the distance is lengthened between poles of the spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0051231 CHEBI:16691 biolink:ChemicalSubstance dethiobiotin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16691 GO:0051247 biolink:BiologicalProcess positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. go-plus.json up regulation of protein metabolic process|activation of protein metabolic process|stimulation of protein metabolic process|up-regulation of protein metabolic process|positive regulation of protein metabolism|upregulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051247 GO:0051248 biolink:BiologicalProcess negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. go-plus.json down regulation of protein metabolic process|downregulation of protein metabolic process|down-regulation of protein metabolic process|negative regulation of protein metabolism|inhibition of protein metabolic process http://purl.obolibrary.org/obo/GO_0051248 GO:0051245 biolink:BiologicalProcess negative regulation of cellular defense response Any process that stops, prevents, or reduces the rate of the cellular defense response. go-plus.json inhibition of cellular defense response|negative regulation of cellular defence response|down regulation of cellular defense response|downregulation of cellular defense response|down-regulation of cellular defense response http://purl.obolibrary.org/obo/GO_0051245 GO:0051246 biolink:BiologicalProcess regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. go-plus.json regulation of protein metabolism http://purl.obolibrary.org/obo/GO_0051246 GO:0051249 biolink:BiologicalProcess regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte activation. go-plus.json http://purl.obolibrary.org/obo/GO_0051249 GO:0016918 biolink:MolecularActivity retinal binding Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina. go-plus.json blue-sensitive opsin|opsin|vitamin A binding|red-sensitive opsin|retinaldehyde binding|short-wave-sensitive opsin|long-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|violet-sensitive opsin http://purl.obolibrary.org/obo/GO_0016918 GO:2000874 biolink:BiologicalProcess regulation of glyoxylate cycle Any process that modulates the frequency, rate or extent of glyoxylate cycle. go-plus.json regulation of glyoxylate bypass http://purl.obolibrary.org/obo/GO_2000874 GO:2000875 biolink:BiologicalProcess negative regulation of glyoxylate cycle Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle. go-plus.json negative regulation of glyoxylate bypass http://purl.obolibrary.org/obo/GO_2000875 GO:0016919 biolink:MolecularActivity obsolete nardilysin activity OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys. go-plus.json N-arginine dibasic convertase activity|NRD convertase activity|nardilysin activity|NRD-convertase activity http://purl.obolibrary.org/obo/GO_0016919 CHEBI:26034 biolink:ChemicalSubstance phosphatidylinositol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26034 GO:2000876 biolink:BiologicalProcess positive regulation of glyoxylate cycle Any process that activates or increases the frequency, rate or extent of glyoxylate cycle. go-plus.json positive regulation of glyoxylate bypass http://purl.obolibrary.org/obo/GO_2000876 GO:2000877 biolink:BiologicalProcess negative regulation of oligopeptide transport Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000877 CHEBI:26036 biolink:ChemicalSubstance phosphatidylinositol monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26036 GO:0016914 biolink:CellularComponent follicle-stimulating hormone complex A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity. go-plus.json FSH complex|follicle stimulating hormone complex http://purl.obolibrary.org/obo/GO_0016914 GO:2000878 biolink:BiologicalProcess positive regulation of oligopeptide transport Any process that activates or increases the frequency, rate or extent of oligopeptide transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000878 GO:2000879 biolink:BiologicalProcess negative regulation of dipeptide transport Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000879 GO:0016915 biolink:MolecularActivity obsolete activin OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone. go-plus.json activin http://purl.obolibrary.org/obo/GO_0016915 GO:1905420 biolink:BiologicalProcess vascular associated smooth muscle cell differentiation involved in phenotypic switching Any vascular smooth muscle cell differentiation that is involved in phenotypic switching. go-plus.json vascular smooth muscle cell differentiation involved in phenotypic switching|VSMC differentiation involved in phenotypic switching|vascular associated smooth muscle cell differentiation involved in phenotypic switching|vascular smooth muscle cell differentiation involved in phenotypic dimorphism|vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|VSMC differentiation involved in phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1905420 GO:0016916 biolink:MolecularActivity obsolete inhibin OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone. go-plus.json inhibin http://purl.obolibrary.org/obo/GO_0016916 GO:0016917 biolink:MolecularActivity GABA receptor activity Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms. go-plus.json gamma-aminobutyrate binding|gamma-aminobutyric acid receptor activity|4-aminobutyrate receptor activity|gamma-aminobutyric acid binding|4-aminobutanoate receptor activity|GABA binding http://purl.obolibrary.org/obo/GO_0016917 GO:1905421 biolink:BiologicalProcess regulation of plant organ morphogenesis Any process that modulates the frequency, rate or extent of plant organ morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905421 GO:0016910 biolink:MolecularActivity obsolete SAP kinase 3 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json SAPK3|SAP kinase 3 activity http://purl.obolibrary.org/obo/GO_0016910 GO:1905411 biolink:BiologicalProcess positive regulation of mitotic cohesin unloading Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading. go-plus.json http://purl.obolibrary.org/obo/GO_1905411 GO:0016911 biolink:MolecularActivity obsolete SAP kinase 4 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json SAPK4|SAP kinase 4 activity http://purl.obolibrary.org/obo/GO_0016911 GO:1905412 biolink:BiologicalProcess negative regulation of mitotic cohesin loading Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading. go-plus.json http://purl.obolibrary.org/obo/GO_1905412 GO:1905413 biolink:BiologicalProcess regulation of dense core granule exocytosis Any process that modulates the frequency, rate or extent of dense core granule exocytosis. go-plus.json regulation of dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1905413 GO:0016912 biolink:MolecularActivity obsolete SAP kinase 5 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json SAPK5|SAP kinase 5 activity http://purl.obolibrary.org/obo/GO_0016912 GO:1905414 biolink:BiologicalProcess negative regulation of dense core granule exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis. go-plus.json down regulation of dense core granule exocytosis|down regulation of dense core vesicle exocytosis|downregulation of dense core granule exocytosis|downregulation of dense core vesicle exocytosis|down-regulation of dense core granule exocytosis|down-regulation of dense core vesicle exocytosis|negative regulation of dense core vesicle exocytosis|inhibition of dense core granule exocytosis|inhibition of dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1905414 GO:0016913 biolink:MolecularActivity follicle-stimulating hormone activity The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis. go-plus.json FSH activity|follitropin activity|follicle stimulating hormone activity http://purl.obolibrary.org/obo/GO_0016913 CHEBI:16689 biolink:ChemicalSubstance D-apiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16689 chebi_ph7_3 GO:1905415 biolink:BiologicalProcess positive regulation of dense core granule exocytosis Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis. go-plus.json up regulation of dense core granule exocytosis|up regulation of dense core vesicle exocytosis|activation of dense core granule exocytosis|activation of dense core vesicle exocytosis|positive regulation of dense core vesicle exocytosis|up-regulation of dense core granule exocytosis|up-regulation of dense core vesicle exocytosis|upregulation of dense core granule exocytosis|upregulation of dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1905415 GO:2000870 biolink:BiologicalProcess regulation of progesterone secretion Any process that modulates the frequency, rate or extent of progesterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000870 GO:1905416 biolink:BiologicalProcess regulation of amoeboid sperm motility Any process that modulates the frequency, rate or extent of amoeboid sperm motility. go-plus.json regulation of ameboid sperm motility|regulation of ameboid sperm movement|regulation of amoeboid sperm movement http://purl.obolibrary.org/obo/GO_1905416 GO:2000871 biolink:BiologicalProcess negative regulation of progesterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000871 GO:1905417 biolink:BiologicalProcess negative regulation of amoeboid sperm motility Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility. go-plus.json downregulation of ameboid sperm motility|negative regulation of ameboid sperm movement|down-regulation of ameboid sperm movement|inhibition of amoeboid sperm motility|down regulation of ameboid sperm motility|inhibition of ameboid sperm motility|negative regulation of amoeboid sperm movement|down-regulation of amoeboid sperm movement|downregulation of ameboid sperm movement|inhibition of amoeboid sperm movement|down regulation of ameboid sperm movement|down regulation of amoeboid sperm motility|inhibition of ameboid sperm movement|downregulation of amoeboid sperm motility|down-regulation of ameboid sperm motility|negative regulation of ameboid sperm motility|down regulation of amoeboid sperm movement|down-regulation of amoeboid sperm motility|downregulation of amoeboid sperm movement http://purl.obolibrary.org/obo/GO_1905417 GO:2000872 biolink:BiologicalProcess positive regulation of progesterone secretion Any process that activates or increases the frequency, rate or extent of progesterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000872 GO:2000873 biolink:BiologicalProcess regulation of histone H4 acetylation involved in response to DNA damage stimulus Any process that modulates the frequency, rate or extent of histone H4 acetylation involved in response to DNA damage stimulus. go-plus.json regulation of histone H4 acetylation involved in response to DNA damage|regulation of histone H4 acetylation involved in cellular response to DNA damage stimulus|regulation of histone H4 acetylation involved in response to genotoxic stress|regulation of histone H4 acetylation involved in DNA damage response|regulation of histone H4 acetylation involved in cellular DNA damage response http://purl.obolibrary.org/obo/GO_2000873 GO:1905418 biolink:BiologicalProcess positive regulation of amoeboid sperm motility Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility. go-plus.json up regulation of amoeboid sperm movement|positive regulation of amoeboid sperm movement|activation of amoeboid sperm movement|up-regulation of amoeboid sperm motility|positive regulation of ameboid sperm movement|upregulation of ameboid sperm motility|up regulation of ameboid sperm movement|upregulation of amoeboid sperm motility|up-regulation of amoeboid sperm movement|up-regulation of ameboid sperm motility|activation of ameboid sperm motility|upregulation of ameboid sperm movement|up regulation of amoeboid sperm motility|upregulation of amoeboid sperm movement|activation of amoeboid sperm motility|up-regulation of ameboid sperm movement|activation of ameboid sperm movement|positive regulation of ameboid sperm motility|up regulation of ameboid sperm motility http://purl.obolibrary.org/obo/GO_1905418 CHEBI:16688 biolink:ChemicalSubstance ecdysone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16688 chebi_ph7_3 CHEBI:16685 biolink:ChemicalSubstance 5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16685 GO:1905419 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905419 GO:0051240 biolink:BiologicalProcess positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. go-plus.json stimulation of multicellular organismal process|up-regulation of multicellular organismal process|activation of multicellular organismal process|up regulation of multicellular organismal process|upregulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051240 CHEBI:16683 biolink:ChemicalSubstance 2,3,6-trihydroxypyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16683 chebi_ph7_3 NCBITaxon:38254 biolink:OrganismalEntity Glaucocystophyceae go-plus.json Glaucophyta|Glaucophyceae|algae|glaucocystophytes http://purl.obolibrary.org/obo/NCBITaxon_38254 CHEBI:16684 biolink:ChemicalSubstance atropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16684 IAO:0000002 biolink:OntologyClass example to be eventually removed go-plus.json http://purl.obolibrary.org/obo/IAO_0000002 CHEBI:16681 biolink:ChemicalSubstance O-sinapoylglucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16681 GO:0051243 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051243 GO:0051244 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051244 CHEBI:16682 biolink:ChemicalSubstance N-acetyl-beta-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16682 GO:0051241 biolink:BiologicalProcess negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. go-plus.json down-regulation of multicellular organismal process|downregulation of multicellular organismal process|down regulation of multicellular organismal process|inhibition of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051241 CHEBI:16680 biolink:ChemicalSubstance S-adenosyl-L-homocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16680 GO:0051242 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051242 GO:0075225 biolink:BiologicalProcess negative regulation of sporangium germination Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination. go-plus.json negative regulation of sporangium germination on or near host http://purl.obolibrary.org/obo/GO_0075225 GO:0051258 biolink:BiologicalProcess protein polymerization The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. go-plus.json protein polymer formation|protein polymer biosynthesis|protein polymer biosynthetic process http://purl.obolibrary.org/obo/GO_0051258 goslim_pir CHEBI:26008 biolink:ChemicalSubstance phenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_26008 GO:0051259 biolink:BiologicalProcess protein complex oligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. go-plus.json protein oligomer assembly|protein oligomerization|protein oligomer biosynthetic process|protein oligomer biosynthesis|protein oligomer formation|protein multimerization http://purl.obolibrary.org/obo/GO_0051259 GO:0075226 biolink:BiologicalProcess encysted zoospore germination The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json encysted zoospore germination on or near host http://purl.obolibrary.org/obo/GO_0075226 GO:0051256 biolink:BiologicalProcess mitotic spindle midzone assembly The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone. go-plus.json spindle midzone formation involved in mitosis|spindle midzone assembly involved in mitosis|mitotic spindle midzone biogenesis|mitotic spindle midzone formation|spindle midzone biogenesis involved in mitosis|mitotic spindle midzone biosynthesis http://purl.obolibrary.org/obo/GO_0051256 GO:0075227 biolink:BiologicalProcess regulation of encysted zoospore germination Any process that modulates the frequency, rate or extent of an encysted zoospore germination. go-plus.json modulation of encysted zoospore germination on or near host|regulation of encysted zoospore germination on or near host http://purl.obolibrary.org/obo/GO_0075227 GO:0051257 biolink:BiologicalProcess meiotic spindle midzone assembly The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis. go-plus.json meiotic spindle midzone biogenesis|spindle midzone formation involved in meiosis|spindle midzone biosynthesis involved in meiosis|spindle midzone assembly involved in meiosis|meiotic spindle midzone formation|spindle midzone biogenesis involved in meiosis|meiotic spindle midzone biosynthesis http://purl.obolibrary.org/obo/GO_0051257 GO:0075228 biolink:BiologicalProcess positive regulation of encysted zoospore germination Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination. go-plus.json positive regulation of encysted zoospore germination on or near host http://purl.obolibrary.org/obo/GO_0075228 GO:0075229 biolink:BiologicalProcess negative regulation of encysted zoospore germination Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination. go-plus.json negative regulation of encysted zoospore germination on or near host http://purl.obolibrary.org/obo/GO_0075229 CHEBI:26004 biolink:ChemicalSubstance phenylpropanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_26004 GO:2000885 biolink:BiologicalProcess galactoglucomannan catabolic process The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan. go-plus.json galactoglucomannan catabolism http://purl.obolibrary.org/obo/GO_2000885 GO:2000886 biolink:BiologicalProcess glucuronoxylan catabolic process The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan. go-plus.json glucuronoxylan catabolism http://purl.obolibrary.org/obo/GO_2000886 GO:2000887 biolink:BiologicalProcess glucuronoarabinoxylan catabolic process The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan. go-plus.json glucuronoarabinoxylan catabolism http://purl.obolibrary.org/obo/GO_2000887 GO:2000888 biolink:BiologicalProcess arabinoxylan-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of an arabinoxylan. go-plus.json arabinoxylan catabolism|arabinoxylan catabolic process http://purl.obolibrary.org/obo/GO_2000888 GO:2000889 biolink:BiologicalProcess cellodextrin metabolic process The chemical reactions and pathways involving a cellodextrin. go-plus.json cellodextrin metabolism http://purl.obolibrary.org/obo/GO_2000889 GO:1905430 biolink:BiologicalProcess cellular response to glycine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. go-plus.json cellular response to aminoacetic acid|cellular response to glycin|cellular response to Gly|cellular response to aminoethanoic acid http://purl.obolibrary.org/obo/GO_1905430 GO:1905431 biolink:BiologicalProcess microcystin transport The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1905431 GO:1905432 biolink:BiologicalProcess regulation of retrograde trans-synaptic signaling by neuropeptide Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. go-plus.json regulation of neuropeptide-mediated retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_1905432 GO:1905422 biolink:BiologicalProcess negative regulation of plant organ morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis. go-plus.json down regulation of plant organ morphogenesis|downregulation of plant organ morphogenesis|down-regulation of plant organ morphogenesis|inhibition of plant organ morphogenesis http://purl.obolibrary.org/obo/GO_1905422 UBERON:0008447 biolink:AnatomicalEntity intertarsal joint Intertarsal articulations are the joints of the tarsus. The specific intertarsal articulations are: Talocalcaneal articulation Talocalcaneonavicular articulation Calcaneocuboid articulation Cuneonavicular articulation Cuboideonavicular articulation Intercuneiform articulation Cuneocuboid articulation go-plus.json articulationes intertarsale|intertarsal joint|intertarsal|articulationes intertarsales|articulationes intertarseae|tarsal joints|intertarsal articulation|intermetatarsal joint|tarsal joint http://purl.obolibrary.org/obo/UBERON_0008447 GO:1905423 biolink:BiologicalProcess positive regulation of plant organ morphogenesis Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis. go-plus.json upregulation of plant organ morphogenesis|up regulation of plant organ morphogenesis|activation of plant organ morphogenesis|up-regulation of plant organ morphogenesis http://purl.obolibrary.org/obo/GO_1905423 GO:1905424 biolink:BiologicalProcess regulation of Wnt-mediated midbrain dopaminergic neuron differentiation Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. go-plus.json regulation of Wnt-mediated midbrain DA neuron differentiation|regulation of Wingless signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signaling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in mDA neuron differentiation|regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in mDA neuron differentiation|regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt signaling pathway involved in mDA neuron differentiation|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signalling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|regulation of midbrain dopaminergic neuron differentiation by regulation of Wnt signaling|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wg signaling pathway involved in midbrain DA neurogenesis|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate http://purl.obolibrary.org/obo/GO_1905424 GO:1905425 biolink:BiologicalProcess negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. go-plus.json down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt receptor signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt-mediated midbrain DA neuron differentiation|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in mDA neuron differentiation|down-regulation of frizzled signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt signaling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signalling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt signaling pathway involved in mDA neuron differentiation|down regulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt-mediated midbrain DA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-mediated midbrain DA neuron differentiation|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signalling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of Wingless signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signalling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signalling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt-mediated midbrain DA neuron differentiation|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signaling pathway involved in mDA neuron differentiation|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of midbrain dopaminergic neuron differentiation by negative regulation of Wnt signaling|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of frizzled signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of Wg signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signaling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|downregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt-mediated midbrain DA neuron differentiation|inhibition of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production http://purl.obolibrary.org/obo/GO_1905425 GO:2000880 biolink:BiologicalProcess positive regulation of dipeptide transport Any process that activates or increases the frequency, rate or extent of dipeptide transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000880 GO:1905426 biolink:BiologicalProcess positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. go-plus.json up-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signaling pathway involved in mDA neuron differentiation|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|upregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|upregulation of Wg signalling pathway involved in midbrain DA neurogenesis|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt signaling pathway involved in mDA neuron differentiation|up regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|activation of Wg signalling pathway involved in midbrain dopaminergic neuron production|activation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt-mediated midbrain DA neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wg signalling pathway involved in mDA neuron differentiation|positive regulation of Wg signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-mediated midbrain DA neuron differentiation|activation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of frizzled signalling pathway involved in mDA neuron differentiation|up regulation of Wingless signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt-mediated midbrain DA neuron differentiation|up-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signalling pathway involved in mDA neuron differentiation|upregulation of frizzled signaling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signalling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signalling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|activation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt signaling pathway involved in mDA neuron differentiation|up-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt signaling pathway involved in mDA neuron differentiation|up-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in mDA neuron differentiation|positive regulation of Wingless signalling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-mediated midbrain DA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|activation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wg signaling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signaling pathway involved in mDA neuron differentiation|positive regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wg signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of midbrain dopaminergic neuron differentiation by positive regulation of Wnt signaling|up-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signalling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in midbrain DA neurogenesis|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wg signaling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|activation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|activation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signalling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signaling pathway involved in mDA neuron differentiation http://purl.obolibrary.org/obo/GO_1905426 GO:2000881 biolink:BiologicalProcess regulation of starch catabolic process Any process that modulates the frequency, rate or extent of starch catabolic process. go-plus.json regulation of starch breakdown|regulation of starch catabolism|regulation of starch degradation http://purl.obolibrary.org/obo/GO_2000881 GO:1905427 biolink:BiologicalProcess intracellular signal transduction involved in positive regulation of cell growth Any intracellular signal transduction that is involved in positive regulation of cell growth. go-plus.json intracellular signaling chain involved in upregulation of cell growth|protein kinase cascade involved in stimulation of cell growth|intracellular signaling cascade involved in activation of cell growth|intracellular protein kinase cascade involved in activation of cell growth|intracellular signaling pathway involved in stimulation of cell growth|intracellular signaling cascade involved in up regulation of cell growth|protein kinase cascade involved in up-regulation of cell growth|intracellular signal transduction involved in upregulation of cell growth|intracellular signaling cascade involved in positive regulation of cell growth|intracellular signal transduction involved in up regulation of cell growth|intracellular signaling pathway involved in up-regulation of cell growth|intracellular signal transduction pathway involved in activation of cell growth|signal transduction via intracellular signaling cascade involved in up regulation of cell growth|signal transmission via intracellular cascade involved in activation of cell growth|protein kinase cascade involved in upregulation of cell growth|signal transmission via intracellular cascade involved in up regulation of cell growth|signal transduction via intracellular signaling cascade involved in positive regulation of cell growth|signal transmission via intracellular cascade involved in positive regulation of cell growth|intracellular signaling chain involved in activation of cell growth|intracellular signaling chain involved in up regulation of cell growth|intracellular signal transduction pathway involved in up regulation of cell growth|intracellular signal transduction involved in stimulation of cell growth|intracellular signaling pathway involved in activation of cell growth|intracellular signal transduction pathway involved in positive regulation of cell growth|signal transduction via intracellular signaling cascade involved in upregulation of cell growth|intracellular signaling cascade involved in stimulation of cell growth|intracellular signaling chain involved in positive regulation of cell growth|intracellular protein kinase cascade involved in up regulation of cell growth|intracellular signaling cascade involved in up-regulation of cell growth|intracellular signal transduction involved in activation of cell growth|intracellular signaling chain involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in stimulation of cell growth|intracellular signaling cascade involved in upregulation of cell growth|intracellular protein kinase cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in upregulation of cell growth|intracellular signal transduction involved in up-regulation of cell growth|signal transmission via intracellular cascade involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in up-regulation of cell growth|intracellular signal transduction pathway involved in stimulation of cell growth|intracellular signal transduction pathway involved in upregulation of cell growth|signal transmission via intracellular cascade involved in up-regulation of cell growth|protein kinase cascade involved in up regulation of cell growth|signal transmission via intracellular cascade involved in upregulation of cell growth|intracellular signaling chain involved in up-regulation of cell growth|intracellular signal transduction pathway involved in up-regulation of cell growth|intracellular signaling pathway involved in up regulation of cell growth|protein kinase cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in stimulation of cell growth|protein kinase cascade involved in activation of cell growth|intracellular signaling pathway involved in upregulation of cell growth|intracellular signaling pathway involved in positive regulation of cell growth|intracellular protein kinase cascade involved in up-regulation of cell growth|signal transduction via intracellular signaling cascade involved in activation of cell growth http://purl.obolibrary.org/obo/GO_1905427 GO:2000882 biolink:BiologicalProcess negative regulation of starch catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process. go-plus.json negative regulation of starch degradation|negative regulation of starch catabolism|negative regulation of starch breakdown http://purl.obolibrary.org/obo/GO_2000882 GO:2000883 biolink:BiologicalProcess positive regulation of starch catabolic process Any process that activates or increases the frequency, rate or extent of starch catabolic process. go-plus.json positive regulation of starch catabolism|positive regulation of starch degradation|positive regulation of starch breakdown http://purl.obolibrary.org/obo/GO_2000883 GO:1905428 biolink:BiologicalProcess regulation of plant organ formation Any process that modulates the frequency, rate or extent of plant organ formation. go-plus.json http://purl.obolibrary.org/obo/GO_1905428 GO:1905429 biolink:BiologicalProcess response to glycine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. go-plus.json response to aminoethanoic acid|response to glycin|response to aminoacetic acid|response to Gly http://purl.obolibrary.org/obo/GO_1905429 GO:2000884 biolink:BiologicalProcess glucomannan catabolic process The chemical reactions and pathways resulting in the breakdown of a glucomannan. go-plus.json glucomannan catabolism http://purl.obolibrary.org/obo/GO_2000884 GO:0051250 biolink:BiologicalProcess negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. go-plus.json down-regulation of lymphocyte activation|inhibition of lymphocyte activation|down regulation of lymphocyte activation|downregulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051250 GO:0051251 biolink:BiologicalProcess positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. go-plus.json up regulation of lymphocyte activation|activation of lymphocyte activation|stimulation of lymphocyte activation|up-regulation of lymphocyte activation|upregulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051251 GO:0075220 biolink:BiologicalProcess positive regulation of zoospore encystment on host Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075220 GO:0051254 biolink:BiologicalProcess positive regulation of RNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. go-plus.json up-regulation of RNA metabolic process|positive regulation of RNA metabolism|upregulation of RNA metabolic process|up regulation of RNA metabolic process|activation of RNA metabolic process|stimulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0051254 GO:0075221 biolink:BiologicalProcess negative regulation of zoospore encystment on host Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075221 GO:0075222 biolink:BiologicalProcess sporangium germination The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores. go-plus.json direct germination on or near host|germination of symbiont sporangium on or near host|sporangium germination on or near host|symbiont sporangium germination on or near host http://purl.obolibrary.org/obo/GO_0075222 GO:0051255 biolink:BiologicalProcess spindle midzone assembly The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap. go-plus.json spindle midzone formation|spindle midzone biosynthesis|spindle midzone biogenesis http://purl.obolibrary.org/obo/GO_0051255 GO:0075223 biolink:BiologicalProcess regulation of sporangium germination Any process that modulates the frequency, rate or extent of sporangium germination. go-plus.json modulation of sporangium germination on or near host|modulation of sporangium germination http://purl.obolibrary.org/obo/GO_0075223 GO:0051252 biolink:BiologicalProcess regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. go-plus.json regulation of RNA metabolism http://purl.obolibrary.org/obo/GO_0051252 GO:0051253 biolink:BiologicalProcess negative regulation of RNA metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. go-plus.json inhibition of RNA metabolic process|negative regulation of RNA metabolism|down regulation of RNA metabolic process|downregulation of RNA metabolic process|down-regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0051253 GO:0075224 biolink:BiologicalProcess positive regulation of sporangium germination Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination. go-plus.json positive regulation of sporangium germination on or near host http://purl.obolibrary.org/obo/GO_0075224 GO:0075214 biolink:BiologicalProcess spore encystment The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json spore encystment on host http://purl.obolibrary.org/obo/GO_0075214 GO:0051269 biolink:MolecularActivity alpha-keto ester reductase activity Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic. EC:1.2.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0051269 GO:0075215 biolink:BiologicalProcess modulation of spore encystment on host Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075215 GO:0051267 biolink:MolecularActivity CP2 mannose-ethanolamine phosphotransferase activity Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2. go-plus.json gpi7 activity|addition of ethanolamine phosphate to mannose of GPI precursor CP2|CP2 EtN-P transferase activity|CP2 ethanolamine phosphate transferase activity|CP2 phosphoethanolamine transferase activity http://purl.obolibrary.org/obo/GO_0051267 GO:0075216 biolink:BiologicalProcess positive regulation of spore encystment on host Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075216 GO:0075217 biolink:BiologicalProcess negative regulation of spore encystment on host Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075217 GO:0051268 biolink:MolecularActivity alpha-keto amide reductase activity Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic. go-plus.json http://purl.obolibrary.org/obo/GO_0051268 GO:0075218 biolink:BiologicalProcess zoospore encystment on host The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075218 GO:0075219 biolink:BiologicalProcess modulation of zoospore encystment on host Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075219 GO:2000896 biolink:BiologicalProcess amylopectin metabolic process The chemical reactions and pathways involving an amylopectin. go-plus.json Amylopectin metabolism http://purl.obolibrary.org/obo/GO_2000896 CHEBI:41630 biolink:ChemicalSubstance S-oxy-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_41630 GO:2000897 biolink:BiologicalProcess amylopectin catabolic process The chemical reactions and pathways resulting in the breakdown of an amylopectin. go-plus.json Amylopectin catabolism http://purl.obolibrary.org/obo/GO_2000897 GO:2000898 biolink:BiologicalProcess regulation of glucomannan catabolic process Any process that modulates the frequency, rate or extent of glucomannan catabolic process. go-plus.json regulation of glucomannan catabolism http://purl.obolibrary.org/obo/GO_2000898 CHEBI:26013 biolink:ChemicalSubstance pheromone go-plus.json http://purl.obolibrary.org/obo/CHEBI_26013 GO:2000899 biolink:BiologicalProcess xyloglucan catabolic process The chemical reactions and pathways resulting in the breakdown of a xyloglucan. go-plus.json xyloglucan catabolism http://purl.obolibrary.org/obo/GO_2000899 GO:1905440 biolink:BiologicalProcess cellular response to chondroitin 6'-sulfate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905440 GO:1905441 biolink:BiologicalProcess response to chondroitin 4'-sulfate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905441 GO:1905442 biolink:BiologicalProcess cellular response to chondroitin 4'-sulfate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905442 GO:1905443 biolink:BiologicalProcess regulation of clathrin coat assembly Any process that modulates the frequency, rate or extent of clathrin coat assembly. go-plus.json regulation of clathrin cage assembly http://purl.obolibrary.org/obo/GO_1905443 GO:1905433 biolink:BiologicalProcess negative regulation of retrograde trans-synaptic signaling by neuropeptide Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. go-plus.json down-regulation of retrograde trans-synaptic signaling by neuropeptide|negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling|inhibition of retrograde trans-synaptic signaling by neuropeptide|inhibition of neuropeptide-mediated retrograde trans-synaptic signaling|down regulation of retrograde trans-synaptic signaling by neuropeptide|downregulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_1905433 GO:1905434 biolink:BiologicalProcess positive regulation of retrograde trans-synaptic signaling by neuropeptide Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. go-plus.json up regulation of retrograde trans-synaptic signaling by neuropeptide|activation of retrograde trans-synaptic signaling by neuropeptide|positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling|up-regulation of retrograde trans-synaptic signaling by neuropeptide|upregulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_1905434 UBERON:0008436 biolink:AnatomicalEntity thoracic vertebral arch A neural arch that is part of a thoracic vertebra. go-plus.json arch of thoracic vertebra http://purl.obolibrary.org/obo/UBERON_0008436 GO:1905435 biolink:BiologicalProcess regulation of histone H3-K4 trimethylation Any process that modulates the frequency, rate or extent of histone H3-K4 trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_1905435 GO:2000890 biolink:BiologicalProcess cellodextrin catabolic process The chemical reactions and pathways resulting in the breakdown of a cellodextrin. go-plus.json cellodextrin catabolism http://purl.obolibrary.org/obo/GO_2000890 GO:2000891 biolink:BiologicalProcess cellobiose metabolic process The chemical reactions and pathways involving a cellobiose. go-plus.json cellobiose metabolism http://purl.obolibrary.org/obo/GO_2000891 GO:1905436 biolink:BiologicalProcess negative regulation of histone H3-K4 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 trimethylation. go-plus.json down-regulation of histone H3-K4 trimethylation|downregulation of histone H3-K4 trimethylation|down regulation of histone H3-K4 trimethylation|inhibition of histone H3-K4 trimethylation http://purl.obolibrary.org/obo/GO_1905436 GO:1905437 biolink:BiologicalProcess positive regulation of histone H3-K4 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation. go-plus.json up-regulation of histone H3-K4 trimethylation|activation of histone H3-K4 trimethylation|up regulation of histone H3-K4 trimethylation|upregulation of histone H3-K4 trimethylation http://purl.obolibrary.org/obo/GO_1905437 GO:2000892 biolink:BiologicalProcess cellobiose catabolic process The chemical reactions and pathways resulting in the breakdown of a cellobiose. go-plus.json cellobiose catabolism http://purl.obolibrary.org/obo/GO_2000892 GO:1905438 biolink:BiologicalProcess non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. go-plus.json non-canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt receptor signalling pathway involved in midbrain DA neurogenesis|beta-catenin-independent Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|beta-catenin-independent Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signalling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate http://purl.obolibrary.org/obo/GO_1905438 GO:2000893 biolink:BiologicalProcess cellotriose metabolic process The chemical reactions and pathways involving a cellotriose. go-plus.json cellotriose metabolism http://purl.obolibrary.org/obo/GO_2000893 GO:2000894 biolink:BiologicalProcess cellotriose catabolic process The chemical reactions and pathways resulting in the breakdown of a cellotriose. go-plus.json cellotriose catabolism http://purl.obolibrary.org/obo/GO_2000894 GO:1905439 biolink:BiologicalProcess response to chondroitin 6'-sulfate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905439 CHEBI:41633 biolink:ChemicalSubstance 24(S),25-epoxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_41633 chebi_ph7_3 GO:2000895 biolink:BiologicalProcess hemicellulose catabolic process The chemical reactions and pathways resulting in the breakdown of a hemicellulose. go-plus.json hemicellulose catabolism http://purl.obolibrary.org/obo/GO_2000895 GO:0051261 biolink:BiologicalProcess protein depolymerization The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. go-plus.json protein polymer catabolic process|protein polymer catabolism|protein polymer degradation|protein polymer breakdown http://purl.obolibrary.org/obo/GO_0051261 goslim_pir GO:0051262 biolink:BiologicalProcess protein tetramerization The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. go-plus.json protein tetramer biosynthesis|protein tetramer biosynthetic process|protein tetramer assembly|protein tetramer formation http://purl.obolibrary.org/obo/GO_0051262 GO:0051260 biolink:BiologicalProcess protein homooligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. go-plus.json protein homooligomer biosynthetic process|protein homooligomer biosynthesis|protein homooligomer formation|protein homooligomer assembly|protein homooligomerization activity http://purl.obolibrary.org/obo/GO_0051260 GO:0051265 biolink:MolecularActivity diolein transacylation activity Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein. go-plus.json dioleoylglycerol transacylase activity|acyl-CoA-independent diolein transacylation|dioleoylglycerol O-acyltransferase activity|DOG transacylation http://purl.obolibrary.org/obo/GO_0051265 GO:0075210 biolink:BiologicalProcess suppression by symbiont of host cAMP-mediated signal transduction Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host cAMP-mediated signaling|negative regulation by symbiont of host cAMP-mediated signal transduction http://purl.obolibrary.org/obo/GO_0075210 GO:0051266 biolink:MolecularActivity sirohydrochlorin ferrochelatase activity Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin. KEGG_REACTION:R02864|RHEA:24360|EC:4.99.1.4|MetaCyc:SIROHEME-FERROCHELAT-RXN go-plus.json Met8P|siroheme ferro-lyase (sirohydrochlorin-forming)|CysG|siroheme synthase activity|SirB|sirohydrochlorin ferro-lyase activity http://purl.obolibrary.org/obo/GO_0051266 GO:0075211 biolink:BiologicalProcess obsolete regulation of transmembrane receptor-mediated cAMP signaling in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of transmembrane receptor-mediated cAMP signal transduction in response to host|regulation of transmembrane receptor-mediated cAMP signalling in response to host|regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075211 UBERON:0008432 biolink:AnatomicalEntity thoracic vertebral foramen A vertebral foramen that is part of a thoracic vertebra. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008432 GO:0075212 biolink:BiologicalProcess obsolete positive regulation of transmembrane receptor-mediated cAMP signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075212 GO:0051263 biolink:BiologicalProcess microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain. RESID:AA0374 go-plus.json microcin E492 formation by siderophore ester modification of peptidyl-serine|microcin E492 synthesis by siderophore ester modification of peptidyl-serine|microcin E492 anabolism by siderophore ester modification of peptidyl-serine http://purl.obolibrary.org/obo/GO_0051263 GO:0051264 biolink:MolecularActivity mono-olein transacylation activity Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol. go-plus.json monooleoylglycerol transacylase activity|monoolein transacylation|monooleoylglycerol O-acyltransferase activity|acyl-CoA-independent mono-olein transacylation|mono-oleoylglycerol O-acyltransferase activity|mono-oleoylglycerol transacylase activity|MOG transacylation http://purl.obolibrary.org/obo/GO_0051264 GO:0075213 biolink:BiologicalProcess obsolete negative regulation of transmembrane receptor-mediated cAMP signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host http://purl.obolibrary.org/obo/GO_0075213 UBERON:0008434 biolink:AnatomicalEntity cervical vertebral arch A neural arch that is part of a cervical vertebra. go-plus.json arch of cervical vertebra http://purl.obolibrary.org/obo/UBERON_0008434 GO:2000827 biolink:BiologicalProcess mitochondrial RNA surveillance The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion. go-plus.json RNA surveillance in mitochondria|RNA quality control in mitochondrion|aberrant RNA catabolic process in mitochondria|aberrant RNA catabolic process in mitochondrion|RNA quality control in mitochondria http://purl.obolibrary.org/obo/GO_2000827 GO:0075247 biolink:BiologicalProcess aeciospore formation The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host. go-plus.json http://purl.obolibrary.org/obo/GO_0075247 GO:2000828 biolink:BiologicalProcess regulation of parathyroid hormone secretion Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. go-plus.json regulation of parathormone secretion|regulation of PTH secretion|regulation of parathyrin secretion http://purl.obolibrary.org/obo/GO_2000828 GO:0075248 biolink:BiologicalProcess regulation of aeciospore formation Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium. go-plus.json http://purl.obolibrary.org/obo/GO_0075248 GO:0051278 biolink:BiologicalProcess fungal-type cell wall polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall. go-plus.json chitin- and beta-glucan-containing cell wall polysaccharide biosynthetic process|cell wall polysaccharide anabolism|cell wall polysaccharide synthesis|cell wall polysaccharide formation http://purl.obolibrary.org/obo/GO_0051278 GO:0075249 biolink:BiologicalProcess positive regulation of aeciospore formation Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium. go-plus.json http://purl.obolibrary.org/obo/GO_0075249 GO:2000829 biolink:BiologicalProcess negative regulation of parathyroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion. go-plus.json negative regulation of parathyrin secretion|negative regulation of parathormone secretion|negative regulation of PTH secretion http://purl.obolibrary.org/obo/GO_2000829 GO:0051279 biolink:BiologicalProcess regulation of release of sequestered calcium ion into cytosol Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. go-plus.json regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+) into cytoplasm|regulation of calcium ion (Ca2+) mobilization|regulation of cytoplasmic release of stored calcium ion (Ca2+)|regulation of release of sequestered calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+) into cytosol|regulation of calcium mobilization http://purl.obolibrary.org/obo/GO_0051279 GO:2000820 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation. go-plus.json negative regulation of transcription from RNA polymerase II promoter, global involved in nonstriated muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in smooth muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter, global involved in smooth muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in nonstriated muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000820 GO:2000821 biolink:BiologicalProcess regulation of grooming behavior Any process that modulates the frequency, rate or extent of grooming behavior. go-plus.json regulation of grooming behaviour http://purl.obolibrary.org/obo/GO_2000821 GO:1905450 biolink:BiologicalProcess negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis. go-plus.json down-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|negative regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|down regulation of IgG-mediated phagocytosis|inhibition of Fc-gamma receptor signalling pathway involved in phagocytosis|downregulation of IgG-mediated phagocytosis|down-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|down-regulation of Fcgamma receptor-mediated phagocytosis|negative regulation of Fc gamma receptor-dependent phagocytosis|negative regulation of Fcgamma receptor-mediated phagocytosis|down-regulation of Fc gamma receptor-dependent phagocytosis|down-regulation of IgG-mediated phagocytosis|negative regulation of IgG-mediated phagocytosis|down regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|downregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|downregulation of Fc gamma receptor-dependent phagocytosis|downregulation of Fcgamma receptor-mediated phagocytosis|down regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|downregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|inhibition of Fc-gamma receptor signaling pathway involved in phagocytosis|inhibition of IgG-mediated phagocytosis|down regulation of Fc gamma receptor-dependent phagocytosis|down regulation of Fcgamma receptor-mediated phagocytosis|inhibition of Fcgamma receptor-mediated phagocytosis|inhibition of Fc gamma receptor-dependent phagocytosis http://purl.obolibrary.org/obo/GO_1905450 GO:2000822 biolink:BiologicalProcess regulation of behavioral fear response Any process that modulates the frequency, rate or extent of behavioral fear response. go-plus.json regulation of behavioural fear response http://purl.obolibrary.org/obo/GO_2000822 GO:1905451 biolink:BiologicalProcess positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis. go-plus.json positive regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|upregulation of Fc gamma receptor-dependent phagocytosis|upregulation of Fcgamma receptor-mediated phagocytosis|upregulation of IgG-mediated phagocytosis|up-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|activation of Fc-gamma receptor signaling pathway involved in phagocytosis|up-regulation of Fc gamma receptor-dependent phagocytosis|up-regulation of Fcgamma receptor-mediated phagocytosis|activation of Fcgamma receptor-mediated phagocytosis|activation of Fc gamma receptor-dependent phagocytosis|up-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|up regulation of IgG-mediated phagocytosis|activation of IgG-mediated phagocytosis|positive regulation of IgG-mediated phagocytosis|up regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|upregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|positive regulation of Fcgamma receptor-mediated phagocytosis|positive regulation of Fc gamma receptor-dependent phagocytosis|up regulation of Fcgamma receptor-mediated phagocytosis|up regulation of Fc gamma receptor-dependent phagocytosis|up-regulation of IgG-mediated phagocytosis|upregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|up regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|activation of Fc-gamma receptor signalling pathway involved in phagocytosis http://purl.obolibrary.org/obo/GO_1905451 GO:2000823 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000823 GO:1905452 biolink:BiologicalProcess obsolete canonical Wnt signaling pathway involved in regulation of stem cell proliferation OBSOLETE. Any canonical Wnt signaling pathway that is involved in regulation of stem cell proliferation. go-plus.json canonical Wnt receptor signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in regulation of stem cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signalling pathway through beta-catenin involved in regulation of stem cell proliferation|Wnt receptor signaling pathway via beta-catenin involved in regulation of stem cell proliferation|frizzled-1 receptor signaling pathway involved in regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_1905452 GO:2000824 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000824 GO:1905453 biolink:BiologicalProcess regulation of myeloid progenitor cell differentiation Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1905453 GO:2000825 biolink:BiologicalProcess positive regulation of androgen receptor activity Any process that activates or increases the frequency, rate or extent of androgen receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_2000825 GO:1905454 biolink:BiologicalProcess negative regulation of myeloid progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation. go-plus.json down regulation of myeloid progenitor cell differentiation|downregulation of myeloid progenitor cell differentiation|down-regulation of myeloid progenitor cell differentiation|inhibition of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1905454 GO:2000826 biolink:BiologicalProcess regulation of heart morphogenesis Any process that modulates the frequency, rate or extent of heart morphogenesis. go-plus.json regulation of cardiac morphogenesis http://purl.obolibrary.org/obo/GO_2000826 GO:1905444 biolink:BiologicalProcess negative regulation of clathrin coat assembly Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly. go-plus.json negative regulation of clathrin cage assembly|down-regulation of clathrin cage assembly|down-regulation of clathrin coat assembly|downregulation of clathrin cage assembly|downregulation of clathrin coat assembly|down regulation of clathrin cage assembly|inhibition of clathrin cage assembly|down regulation of clathrin coat assembly|inhibition of clathrin coat assembly http://purl.obolibrary.org/obo/GO_1905444 GO:1905445 biolink:BiologicalProcess positive regulation of clathrin coat assembly Any process that activates or increases the frequency, rate or extent of clathrin coat assembly. go-plus.json positive regulation of clathrin cage assembly|up regulation of clathrin cage assembly|up regulation of clathrin coat assembly|upregulation of clathrin cage assembly|upregulation of clathrin coat assembly|up-regulation of clathrin cage assembly|activation of clathrin cage assembly|up-regulation of clathrin coat assembly|activation of clathrin coat assembly http://purl.obolibrary.org/obo/GO_1905445 GO:1905446 biolink:BiologicalProcess regulation of mitochondrial ATP synthesis coupled electron transport Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport. go-plus.json regulation of organelle ATP synthesis coupled electron transport|regulation of mitochondrial electron transport http://purl.obolibrary.org/obo/GO_1905446 CHEBI:41625 biolink:ChemicalSubstance chromopyrrolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41625 CHEBI:16658 biolink:ChemicalSubstance flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside]s go-plus.json http://purl.obolibrary.org/obo/CHEBI_16658 chebi_ph7_3 GO:1905447 biolink:BiologicalProcess negative regulation of mitochondrial ATP synthesis coupled electron transport Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport. go-plus.json down-regulation of mitochondrial ATP synthesis coupled electron transport|downregulation of mitochondrial ATP synthesis coupled electron transport|down regulation of mitochondrial ATP synthesis coupled electron transport|inhibition of mitochondrial ATP synthesis coupled electron transport http://purl.obolibrary.org/obo/GO_1905447 CHEBI:16659 biolink:ChemicalSubstance D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16659 chebi_ph7_3 GO:1905448 biolink:BiologicalProcess positive regulation of mitochondrial ATP synthesis coupled electron transport Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport. go-plus.json up-regulation of mitochondrial ATP synthesis coupled electron transport|activation of mitochondrial ATP synthesis coupled electron transport|up regulation of mitochondrial ATP synthesis coupled electron transport|upregulation of mitochondrial ATP synthesis coupled electron transport http://purl.obolibrary.org/obo/GO_1905448 CHEBI:16656 biolink:ChemicalSubstance tropinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16656 GO:1905449 biolink:BiologicalProcess regulation of Fc-gamma receptor signaling pathway involved in phagocytosis Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis. go-plus.json regulation of IgG-mediated phagocytosis|regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|regulation of Fc gamma receptor-dependent phagocytosis|regulation of Fcgamma receptor-mediated phagocytosis http://purl.obolibrary.org/obo/GO_1905449 CHEBI:16654 biolink:ChemicalSubstance (R)-4-dehydropantoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16654 CHEBI:16655 biolink:ChemicalSubstance N-acetyl-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16655 GO:0051272 biolink:BiologicalProcess positive regulation of cellular component movement Any process that activates or increases the frequency, rate or extent of the movement of a cellular component. go-plus.json positive regulation of cellular component motion http://purl.obolibrary.org/obo/GO_0051272 CHEBI:16652 biolink:ChemicalSubstance 1,4-diguanidinobutane go-plus.json http://purl.obolibrary.org/obo/CHEBI_16652 GO:0051273 biolink:BiologicalProcess beta-glucan metabolic process The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds. go-plus.json beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0051273 GO:0075240 biolink:BiologicalProcess regulation of zoospore formation Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075240 CHEBI:16653 biolink:ChemicalSubstance cycloeucalenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16653 chebi_ph7_3 GO:0075241 biolink:BiologicalProcess positive regulation of zoospore formation Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075241 GO:0051270 biolink:BiologicalProcess regulation of cellular component movement Any process that modulates the frequency, rate or extent of the movement of a cellular component. go-plus.json regulation of cellular component motion|regulation of cell movement http://purl.obolibrary.org/obo/GO_0051270 CHEBI:16650 biolink:ChemicalSubstance UDP-N-acetyl-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16650 GO:0075242 biolink:BiologicalProcess negative regulation of zoospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075242 CHEBI:16651 biolink:ChemicalSubstance (S)-lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16651 chebi_ph7_3 GO:0051271 biolink:BiologicalProcess negative regulation of cellular component movement Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component. go-plus.json negative regulation of cellular component motion http://purl.obolibrary.org/obo/GO_0051271 GO:0075243 biolink:BiologicalProcess oospore formation The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075243 GO:0051276 biolink:BiologicalProcess chromosome organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. go-plus.json nuclear genome maintenance|maintenance of genome integrity|chromosome organization and biogenesis|chromosome organisation http://purl.obolibrary.org/obo/GO_0051276 goslim_generic|goslim_chembl|goslim_pir|goslim_drosophila GO:0075244 biolink:BiologicalProcess regulation of oospore formation Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075244 GO:0051277 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051277 GO:0075245 biolink:BiologicalProcess positive regulation of oospore formation Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075245 GO:0051274 biolink:BiologicalProcess beta-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of beta-glucans. go-plus.json beta-glucan anabolism|beta-glucan synthesis|beta-glucan biosynthesis|beta-glucan formation http://purl.obolibrary.org/obo/GO_0051274 GO:0075246 biolink:BiologicalProcess negative regulation of oospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075246 GO:0051275 biolink:BiologicalProcess beta-glucan catabolic process The chemical reactions and pathways resulting in the breakdown of beta-glucans. go-plus.json beta-glucan breakdown|beta-glucan catabolism|beta-glucan degradation http://purl.obolibrary.org/obo/GO_0051275 GO:0075236 biolink:BiologicalProcess obsolete positive regulation of zoospore movement on or near host OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075236 GO:2000838 biolink:BiologicalProcess negative regulation of androstenedione secretion Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion. go-plus.json negative regulation of androst-4-ene-3,17-dione secretion http://purl.obolibrary.org/obo/GO_2000838 GO:2000839 biolink:BiologicalProcess positive regulation of androstenedione secretion Any process that activates or increases the frequency, rate or extent of androstenedione secretion. go-plus.json positive regulation of androst-4-ene-3,17-dione secretion http://purl.obolibrary.org/obo/GO_2000839 GO:0075237 biolink:BiologicalProcess obsolete obsolete negative regulation of zoospore movement on or near host OBSOLETE. OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075237 GO:0075238 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075238 GO:0051289 biolink:BiologicalProcess protein homotetramerization The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits. go-plus.json protein homotetramer formation|protein homotetramer biosynthetic process|protein homotetramer biosynthesis|protein homotetramer assembly http://purl.obolibrary.org/obo/GO_0051289 GO:0075239 biolink:BiologicalProcess zoospore formation The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. go-plus.json http://purl.obolibrary.org/obo/GO_0075239 GO:2000830 biolink:BiologicalProcess positive regulation of parathyroid hormone secretion Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. go-plus.json positive regulation of parathyrin secretion|positive regulation of PTH secretion|positive regulation of parathormone secretion http://purl.obolibrary.org/obo/GO_2000830 GO:2000831 biolink:BiologicalProcess regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of steroid hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000831 GO:1905460 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. go-plus.json down-regulation of vascular associated smooth muscle cell apoptotic process|inhibition of vascular smooth muscle cell apoptotic process|inhibition of vascular smooth muscle cell apoptosis|down-regulation of VSMC apoptosis|downregulation of vascular associated smooth muscle cell apoptosis|negative regulation of VSMC apoptosis|down regulation of vascular associated smooth muscle cell apoptosis|down-regulation of VSMC apoptotic process|downregulation of vascular associated smooth muscle cell apoptotic process|negative regulation of VSMC apoptotic process|down regulation of vascular smooth muscle cell apoptosis|downregulation of VSMC apoptosis|down regulation of vascular associated smooth muscle cell apoptotic process|downregulation of vascular smooth muscle cell apoptosis|inhibition of vascular associated smooth muscle cell apoptosis|inhibition of vascular associated smooth muscle cell apoptotic process|down regulation of vascular smooth muscle cell apoptotic process|down regulation of VSMC apoptosis|downregulation of VSMC apoptotic process|downregulation of vascular smooth muscle cell apoptotic process|down regulation of VSMC apoptotic process|negative regulation of vascular smooth muscle cell apoptosis|down-regulation of vascular smooth muscle cell apoptosis|inhibition of VSMC apoptotic process|inhibition of VSMC apoptosis|down-regulation of vascular associated smooth muscle cell apoptosis|negative regulation of vascular associated smooth muscle cell apoptosis|negative regulation of vascular smooth muscle cell apoptotic process|down-regulation of vascular smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_1905460 GO:2000832 biolink:BiologicalProcess negative regulation of steroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000832 GO:1905461 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. go-plus.json positive regulation of vascular associated smooth muscle cell apoptosis|up regulation of vascular associated smooth muscle cell apoptosis|activation of VSMC apoptotic process|up-regulation of VSMC apoptotic process|activation of VSMC apoptosis|up-regulation of vascular smooth muscle cell apoptotic process|up regulation of vascular associated smooth muscle cell apoptotic process|upregulation of vascular smooth muscle cell apoptosis|positive regulation of VSMC apoptosis|up regulation of VSMC apoptosis|upregulation of vascular associated smooth muscle cell apoptosis|upregulation of vascular smooth muscle cell apoptotic process|positive regulation of VSMC apoptotic process|up regulation of VSMC apoptotic process|upregulation of vascular associated smooth muscle cell apoptotic process|up regulation of vascular smooth muscle cell apoptosis|positive regulation of vascular smooth muscle cell apoptosis|upregulation of VSMC apoptosis|up-regulation of vascular associated smooth muscle cell apoptosis|up regulation of vascular smooth muscle cell apoptotic process|activation of vascular smooth muscle cell apoptotic process|activation of vascular smooth muscle cell apoptosis|positive regulation of vascular smooth muscle cell apoptotic process|up-regulation of vascular associated smooth muscle cell apoptotic process|upregulation of VSMC apoptotic process|activation of vascular associated smooth muscle cell apoptosis|activation of vascular associated smooth muscle cell apoptotic process|up-regulation of VSMC apoptosis|up-regulation of vascular smooth muscle cell apoptosis http://purl.obolibrary.org/obo/GO_1905461 GO:2000833 biolink:BiologicalProcess positive regulation of steroid hormone secretion Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000833 GO:1905462 biolink:BiologicalProcess regulation of DNA duplex unwinding Any process that modulates the frequency, rate or extent of DNA duplex unwinding. go-plus.json regulation of duplex DNA melting|regulation of DNA unwinding http://purl.obolibrary.org/obo/GO_1905462 GO:2000834 biolink:BiologicalProcess regulation of androgen secretion Any process that modulates the frequency, rate or extent of androgen secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000834 GO:1905463 biolink:BiologicalProcess negative regulation of DNA duplex unwinding Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding. go-plus.json downregulation of duplex DNA melting|down regulation of duplex DNA melting|inhibition of duplex DNA melting|down-regulation of DNA duplex unwinding|down regulation of DNA unwinding|downregulation of DNA unwinding|downregulation of DNA duplex unwinding|down regulation of DNA duplex unwinding|negative regulation of DNA unwinding|inhibition of DNA duplex unwinding|down-regulation of DNA unwinding|down-regulation of duplex DNA melting|negative regulation of duplex DNA melting|inhibition of DNA unwinding http://purl.obolibrary.org/obo/GO_1905463 GO:2000835 biolink:BiologicalProcess negative regulation of androgen secretion Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000835 GO:1905464 biolink:BiologicalProcess positive regulation of DNA duplex unwinding Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding. go-plus.json up-regulation of DNA duplex unwinding|activation of DNA duplex unwinding|upregulation of DNA unwinding|upregulation of duplex DNA melting|up regulation of DNA duplex unwinding|up regulation of DNA unwinding|activation of DNA unwinding|up-regulation of duplex DNA melting|positive regulation of DNA unwinding|activation of duplex DNA melting|upregulation of DNA duplex unwinding|up-regulation of DNA unwinding|positive regulation of duplex DNA melting|up regulation of duplex DNA melting http://purl.obolibrary.org/obo/GO_1905464 GO:2000836 biolink:BiologicalProcess positive regulation of androgen secretion Any process that activates or increases the frequency, rate or extent of androgen secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000836 GO:1905465 biolink:BiologicalProcess regulation of G-quadruplex DNA unwinding Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding. go-plus.json http://purl.obolibrary.org/obo/GO_1905465 GO:2000837 biolink:BiologicalProcess regulation of androstenedione secretion Any process that modulates the frequency, rate or extent of androstenedione secretion. go-plus.json regulation of androst-4-ene-3,17-dione secretion http://purl.obolibrary.org/obo/GO_2000837 GO:1905455 biolink:BiologicalProcess positive regulation of myeloid progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation. go-plus.json upregulation of myeloid progenitor cell differentiation|up regulation of myeloid progenitor cell differentiation|activation of myeloid progenitor cell differentiation|up-regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1905455 GO:1905456 biolink:BiologicalProcess regulation of lymphoid progenitor cell differentiation Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1905456 CHEBI:16647 biolink:ChemicalSubstance L-fuculose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16647 GO:1905457 biolink:BiologicalProcess negative regulation of lymphoid progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation. go-plus.json downregulation of lymphoid progenitor cell differentiation|down regulation of lymphoid progenitor cell differentiation|inhibition of lymphoid progenitor cell differentiation|down-regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1905457 GO:1905458 biolink:BiologicalProcess positive regulation of lymphoid progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation. go-plus.json up regulation of lymphoid progenitor cell differentiation|upregulation of lymphoid progenitor cell differentiation|up-regulation of lymphoid progenitor cell differentiation|activation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1905458 CHEBI:16648 biolink:ChemicalSubstance dialkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16648 GO:1905459 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell apoptotic process Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. go-plus.json regulation of vascular smooth muscle cell apoptosis|regulation of VSMC apoptosis|regulation of vascular smooth muscle cell apoptotic process|regulation of VSMC apoptotic process|regulation of vascular associated smooth muscle cell apoptosis http://purl.obolibrary.org/obo/GO_1905459 CHEBI:16645 biolink:ChemicalSubstance preuroporphyrinogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_16645 GO:0051280 biolink:BiologicalProcess negative regulation of release of sequestered calcium ion into cytosol Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. go-plus.json downregulation of release of sequestered calcium ion into cytosol|negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|negative regulation of calcium mobilization|negative regulation of cytosolic release of stored calcium ion (Ca2+)|negative regulation of cytosolic release of sequestered calcium ion (Ca2+)|negative regulation of release of sequestered calcium ion into cytoplasm|negative regulation of calcium ion (Ca2+) mobilization|negative regulation of release of stored calcium ion (Ca2+) into cytoplasm|down-regulation of release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion (Ca2+)|negative regulation of release of stored calcium ion (Ca2+) into cytosol|inhibition of release of sequestered calcium ion into cytosol|negative regulation of release of stored calcium ion (Ca2+)|down regulation of release of sequestered calcium ion into cytosol|negative regulation of cytoplasmic release of stored calcium ion (Ca2+) http://purl.obolibrary.org/obo/GO_0051280 CHEBI:16646 biolink:ChemicalSubstance carbohydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16646 CHEBI:16643 biolink:ChemicalSubstance L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16643 CHEBI:16641 biolink:ChemicalSubstance ethyl (R)-3-hydroxyhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16641 chebi_ph7_3 GO:0051283 biolink:BiologicalProcess negative regulation of sequestering of calcium ion Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. go-plus.json down-regulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) sequestration|negative regulation of sequestering of calcium ion (Ca2+)|inhibition of sequestering of calcium ion|negative regulation of retention of calcium ion (Ca2+)|negative regulation of storage of calcium ion (Ca2+)|down regulation of sequestering of calcium ion|negative regulation of sequestration of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) retention|negative regulation of calcium ion (Ca2+) sequestering|downregulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) storage http://purl.obolibrary.org/obo/GO_0051283 GO:0051284 biolink:BiologicalProcess positive regulation of sequestering of calcium ion Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. go-plus.json positive regulation of calcium ion (Ca2+) retention|up regulation of sequestering of calcium ion|activation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) storage|stimulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestration|positive regulation of retention of calcium ion (Ca2+)|up-regulation of sequestering of calcium ion|positive regulation of storage of calcium ion (Ca2+)|positive regulation of sequestering of calcium ion (Ca2+)|positive regulation of sequestration of calcium ion (Ca2+)|upregulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestering http://purl.obolibrary.org/obo/GO_0051284 GO:0051281 biolink:BiologicalProcess positive regulation of release of sequestered calcium ion into cytosol Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. go-plus.json positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|positive regulation of cytoplasmic release of stored calcium ion (Ca2+)|positive regulation of cytosolic release of sequestered calcium ion (Ca2+)|positive regulation of release of sequestered calcium ion into cytoplasm|up regulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+) into cytoplasm|activation of release of sequestered calcium ion into cytosol|positive regulation of calcium ion (Ca2+) mobilization|positive regulation of release of sequestered calcium ion (Ca2+)|positive regulation of cytosolic release of stored calcium ion (Ca2+)|positive regulation of calcium mobilization|stimulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+) into cytosol|up-regulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+)|upregulation of release of sequestered calcium ion into cytosol http://purl.obolibrary.org/obo/GO_0051281 GO:0075230 biolink:BiologicalProcess obsolete spore movement on or near host OBSOLETE. Any process involved in the directed movement of a motile spore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075230 GO:0051282 biolink:BiologicalProcess regulation of sequestering of calcium ion Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. go-plus.json regulation of retention of calcium ion (Ca2+)|regulation of storage of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) retention|regulation of calcium ion (Ca2+) storage|regulation of sequestration of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) sequestration|regulation of calcium ion (Ca2+) sequestering|regulation of sequestering of calcium ion (Ca2+) http://purl.obolibrary.org/obo/GO_0051282 GO:0075231 biolink:BiologicalProcess obsolete modulation of spore movement on or near host OBSOLETE. Any process that modulates the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075231 GO:0051287 biolink:MolecularActivity NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. go-plus.json NAD+ or NADH binding|NAD or NADH binding|nicotinamide adenine dinucleotide binding http://purl.obolibrary.org/obo/GO_0051287 goslim_chembl GO:0075232 biolink:BiologicalProcess obsolete positive regulation of spore movement on or near host OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075232 GO:0075233 biolink:BiologicalProcess obsolete negative regulation of spore movement on or near host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075233 GO:0051288 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051288 GO:0051285 biolink:CellularComponent cell cortex of cell tip The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell. go-plus.json cell cortex of cell end http://purl.obolibrary.org/obo/GO_0051285 GO:0075234 biolink:BiologicalProcess obsolete zoospore movement on or near host OBSOLETE. Any process involved in the directed movement of a zoospore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json zoospore motility on or near host http://purl.obolibrary.org/obo/GO_0075234 GO:0075235 biolink:BiologicalProcess obsolete modulation of zoospore movement on or near host OBSOLETE. Any process that modulates the frequency, rate or extent of zoospore movement on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of zoospore motility on or near host http://purl.obolibrary.org/obo/GO_0075235 GO:0051286 biolink:CellularComponent cell tip The region at the end of the longest axis of a cylindrical or elongated cell. go-plus.json cell end http://purl.obolibrary.org/obo/GO_0051286 GO:0075269 biolink:BiologicalProcess positive regulation of aecium development Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075269 GO:2000849 biolink:BiologicalProcess regulation of glucocorticoid secretion Any process that modulates the frequency, rate or extent of glucocorticoid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000849 GO:2000841 biolink:BiologicalProcess negative regulation of dehydroepiandrosterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion. go-plus.json negative regulation of dehydroisoandrosterone secretion|negative regulation of 3beta-hydroxyandrost-5-en-17-one secretion|negative regulation of DHEA secretion http://purl.obolibrary.org/obo/GO_2000841 GO:1905470 biolink:BiologicalProcess positive regulation of clathrin-coated pit assembly Any process that activates or increases the frequency, rate or extent of clathrin-coated pit assembly. go-plus.json upregulation of clathrin-coated pit assembly|upregulation of coated pit formation|up regulation of coated pit assembly|up regulation of clathrin-coated pit formation|positive regulation of coated pit assembly|activation of coated pit assembly|activation of clathrin-coated pit formation|positive regulation of clathrin-coated pit formation|up-regulation of clathrin-coated pit assembly|up-regulation of coated pit formation|activation of clathrin-coated pit assembly|activation of coated pit formation|up-regulation of coated pit assembly|up-regulation of clathrin-coated pit formation|positive regulation of coated pit formation|up regulation of clathrin-coated pit assembly|up regulation of coated pit formation|upregulation of coated pit assembly|upregulation of clathrin-coated pit formation http://purl.obolibrary.org/obo/GO_1905470 GO:2000842 biolink:BiologicalProcess positive regulation of dehydroepiandrosterone secretion Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion. go-plus.json positive regulation of DHEA secretion|positive regulation of dehydroisoandrosterone secretion|positive regulation of 3beta-hydroxyandrost-5-en-17-one secretion http://purl.obolibrary.org/obo/GO_2000842 GO:2000843 biolink:BiologicalProcess regulation of testosterone secretion Any process that modulates the frequency, rate or extent of testosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000843 GO:1905471 biolink:BiologicalProcess regulation of histone H3-K79 dimethylation Any process that modulates the frequency, rate or extent of histone H3-K79 dimethylation. go-plus.json regulation of histone H3 K79 dimethylation|regulation of histone lysine H3 K79 dimethylation http://purl.obolibrary.org/obo/GO_1905471 GO:1905472 biolink:BiologicalProcess negative regulation of histone H3-K79 dimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 dimethylation. go-plus.json downregulation of histone H3 K79 dimethylation|down-regulation of histone H3-K79 dimethylation|down regulation of histone H3 K79 dimethylation|negative regulation of histone lysine H3 K79 dimethylation|down-regulation of histone lysine H3 K79 dimethylation|inhibition of histone H3 K79 dimethylation|inhibition of histone lysine H3 K79 dimethylation|downregulation of histone H3-K79 dimethylation|down regulation of histone H3-K79 dimethylation|inhibition of histone H3-K79 dimethylation|down-regulation of histone H3 K79 dimethylation|negative regulation of histone H3 K79 dimethylation|down regulation of histone lysine H3 K79 dimethylation|downregulation of histone lysine H3 K79 dimethylation http://purl.obolibrary.org/obo/GO_1905472 GO:2000844 biolink:BiologicalProcess negative regulation of testosterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000844 GO:1905473 biolink:BiologicalProcess positive regulation of histone H3-K79 dimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation. go-plus.json up-regulation of histone H3-K79 dimethylation|activation of histone H3-K79 dimethylation|up regulation of histone H3 K79 dimethylation|up regulation of histone lysine H3 K79 dimethylation|activation of histone lysine H3 K79 dimethylation|positive regulation of histone lysine H3 K79 dimethylation|upregulation of histone H3 K79 dimethylation|up regulation of histone H3-K79 dimethylation|up-regulation of histone lysine H3 K79 dimethylation|up-regulation of histone H3 K79 dimethylation|activation of histone H3 K79 dimethylation|upregulation of histone H3-K79 dimethylation|upregulation of histone lysine H3 K79 dimethylation|positive regulation of histone H3 K79 dimethylation http://purl.obolibrary.org/obo/GO_1905473 GO:2000845 biolink:BiologicalProcess positive regulation of testosterone secretion Any process that activates or increases the frequency, rate or extent of testosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000845 GO:1905474 biolink:BiologicalProcess canonical Wnt signaling pathway involved in stem cell proliferation Any canonical Wnt signaling pathway that is involved in stem cell proliferation. go-plus.json Wnt receptor signalling pathway through beta-catenin involved in stem cell proliferation|canonical Wnt-activated signaling pathway involved in stem cell proliferation|Wnt receptor signaling pathway via beta-catenin involved in stem cell proliferation|frizzled-1 receptor signaling pathway involved in stem cell proliferation|canonical Wnt receptor signaling pathway involved in stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in stem cell proliferation http://purl.obolibrary.org/obo/GO_1905474 GO:2000846 biolink:BiologicalProcess regulation of corticosteroid hormone secretion Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. go-plus.json regulation of corticosteroid secretion http://purl.obolibrary.org/obo/GO_2000846 GO:1905475 biolink:BiologicalProcess regulation of protein localization to membrane Any process that modulates the frequency, rate or extent of protein localization to membrane. go-plus.json regulation of protein localisation in membrane|regulation of protein localization in membrane http://purl.obolibrary.org/obo/GO_1905475 GO:2000847 biolink:BiologicalProcess negative regulation of corticosteroid hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion. go-plus.json negative regulation of corticosteroid secretion http://purl.obolibrary.org/obo/GO_2000847 GO:1905476 biolink:BiologicalProcess negative regulation of protein localization to membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. go-plus.json inhibition of protein localization to membrane|down regulation of protein localisation in membrane|inhibition of protein localisation in membrane|downregulation of protein localization in membrane|down regulation of protein localization in membrane|inhibition of protein localization in membrane|down-regulation of protein localization to membrane|negative regulation of protein localisation in membrane|down-regulation of protein localisation in membrane|downregulation of protein localization to membrane|down-regulation of protein localization in membrane|negative regulation of protein localization in membrane|downregulation of protein localisation in membrane|down regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1905476 GO:2000848 biolink:BiologicalProcess positive regulation of corticosteroid hormone secretion Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion. go-plus.json positive regulation of corticosteroid secretion http://purl.obolibrary.org/obo/GO_2000848 GO:1905466 biolink:BiologicalProcess negative regulation of G-quadruplex DNA unwinding Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding. go-plus.json downregulation of G-quadruplex DNA unwinding|down regulation of G-quadruplex DNA unwinding|inhibition of G-quadruplex DNA unwinding|down-regulation of G-quadruplex DNA unwinding http://purl.obolibrary.org/obo/GO_1905466 GO:1905467 biolink:BiologicalProcess positive regulation of G-quadruplex DNA unwinding Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding. go-plus.json up regulation of G-quadruplex DNA unwinding|upregulation of G-quadruplex DNA unwinding|up-regulation of G-quadruplex DNA unwinding|activation of G-quadruplex DNA unwinding http://purl.obolibrary.org/obo/GO_1905467 GO:1905468 biolink:BiologicalProcess regulation of clathrin-coated pit assembly Any process that modulates the frequency, rate or extent of clathrin-coated pit assembly. go-plus.json regulation of coated pit formation|regulation of coated pit assembly|regulation of clathrin-coated pit formation http://purl.obolibrary.org/obo/GO_1905468 GO:1905469 biolink:BiologicalProcess negative regulation of clathrin-coated pit assembly Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-coated pit assembly. go-plus.json down-regulation of coated pit assembly|negative regulation of coated pit assembly|negative regulation of clathrin-coated pit formation|down-regulation of clathrin-coated pit formation|down-regulation of clathrin-coated pit assembly|inhibition of coated pit assembly|negative regulation of coated pit formation|down-regulation of coated pit formation|inhibition of clathrin-coated pit formation|downregulation of clathrin-coated pit assembly|downregulation of coated pit formation|down regulation of coated pit assembly|down regulation of clathrin-coated pit assembly|down regulation of clathrin-coated pit formation|down regulation of coated pit formation|inhibition of clathrin-coated pit assembly|inhibition of coated pit formation|downregulation of coated pit assembly|downregulation of clathrin-coated pit formation http://purl.obolibrary.org/obo/GO_1905469 GO:0051290 biolink:BiologicalProcess protein heterotetramerization The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical. go-plus.json protein heterotetramer assembly|protein heterotetramer formation|protein heterotetramer biosynthetic process|protein heterotetramer biosynthesis http://purl.obolibrary.org/obo/GO_0051290 GO:0051291 biolink:BiologicalProcess protein heterooligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. go-plus.json protein heterooligomer assembly|protein heterooligomer formation|protein heterooligomer biosynthetic process|protein heterooligomer biosynthesis http://purl.obolibrary.org/obo/GO_0051291 GO:2000840 biolink:BiologicalProcess regulation of dehydroepiandrosterone secretion Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion. go-plus.json regulation of DHEA secretion|regulation of dehydroisoandrosterone secretion|regulation of 3beta-hydroxyandrost-5-en-17-one secretion http://purl.obolibrary.org/obo/GO_2000840 GO:0075260 biolink:BiologicalProcess regulation of spore-bearing organ development Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores. go-plus.json http://purl.obolibrary.org/obo/GO_0075260 GO:0051294 biolink:BiologicalProcess establishment of spindle orientation Any process that set the alignment of spindle relative to other cellular structures. go-plus.json orienting of spindle|spindle orientation http://purl.obolibrary.org/obo/GO_0051294 GO:0075261 biolink:BiologicalProcess positive regulation of spore-bearing organ development Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores. go-plus.json http://purl.obolibrary.org/obo/GO_0075261 GO:0051295 biolink:BiologicalProcess establishment of meiotic spindle localization The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs. go-plus.json establishment of meiotic spindle localisation|spindle positioning involved in meiotic cell cycle|spindle positioning during meiosis|meiotic spindle positioning http://purl.obolibrary.org/obo/GO_0051295 CHEBI:16675 biolink:ChemicalSubstance quinolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16675 GO:0075262 biolink:BiologicalProcess negative regulation of spore-bearing organ development Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores. go-plus.json http://purl.obolibrary.org/obo/GO_0075262 GO:0051292 biolink:BiologicalProcess nuclear pore complex assembly The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex. go-plus.json nuclear pore assembly|nuclear pore biogenesis|nuclear pore complex biosynthesis|nuclear pore complex formation|NPC assembly|nuclear pore complex biogenesis|nuclear pore biosynthesis|nuclear pore formation http://purl.obolibrary.org/obo/GO_0051292 GO:0075263 biolink:BiologicalProcess oogonium development The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes. go-plus.json http://purl.obolibrary.org/obo/GO_0075263 GO:0051293 biolink:BiologicalProcess establishment of spindle localization The directed movement of the spindle to a specific location in the cell. go-plus.json spindle positioning|establishment of spindle localisation http://purl.obolibrary.org/obo/GO_0051293 GO:0075264 biolink:BiologicalProcess regulation of oogonium development Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes. go-plus.json http://purl.obolibrary.org/obo/GO_0075264 CHEBI:16673 biolink:ChemicalSubstance protochlorophyllide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16673 GO:0075265 biolink:BiologicalProcess positive regulation of oogonium development Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes. go-plus.json http://purl.obolibrary.org/obo/GO_0075265 CHEBI:41609 biolink:ChemicalSubstance carbonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_41609 GO:0051298 biolink:BiologicalProcess centrosome duplication The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. go-plus.json centrosome replication http://purl.obolibrary.org/obo/GO_0051298 CHEBI:16670 biolink:ChemicalSubstance peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16670 CHEBI:16671 biolink:ChemicalSubstance 4-guanidinobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_16671 GO:0051299 biolink:BiologicalProcess centrosome separation The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0051299 GO:0075266 biolink:BiologicalProcess negative regulation of oogonium development Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes. go-plus.json http://purl.obolibrary.org/obo/GO_0075266 GO:0051296 biolink:BiologicalProcess establishment of meiotic spindle orientation Any process that set the alignment of meiotic spindle relative to other cellular structures. go-plus.json meiotic spindle orientation|establishment of spindle orientation involved in meiotic cell cycle|establishment of spindle orientation during meiosis|orienting of meiotic spindle http://purl.obolibrary.org/obo/GO_0051296 GO:0075267 biolink:BiologicalProcess aecium development The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium. go-plus.json http://purl.obolibrary.org/obo/GO_0075267 GO:0075268 biolink:BiologicalProcess regulation of aecium development Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075268 GO:0051297 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051297 GO:0075258 biolink:BiologicalProcess negative regulation of teliospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0075258 GO:0075259 biolink:BiologicalProcess spore-bearing structure development The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores. go-plus.json fruiting structure development|sporangium development|sporophore development|spore-bearing organ development http://purl.obolibrary.org/obo/GO_0075259 GO:1905480 biolink:BiologicalProcess positive regulation of glutamate-ammonia ligase activity Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity. go-plus.json upregulation of glutamine synthetase activity|upregulation of L-glutamine synthetase activity|upregulation of glutamylhydroxamic synthetase activity|upregulation of glutamate-ammonia ligase activity|up-regulation of L-glutamate:ammonia ligase (ADP-forming)|activation of L-glutamate:ammonia ligase (ADP-forming)|up regulation of glutamine synthetase activity|up regulation of L-glutamine synthetase activity|activation of glutamine synthetase activity|positive regulation of glutamine synthetase activity|up-regulation of glutamylhydroxamic synthetase activity|activation of L-glutamine synthetase activity|activation of glutamylhydroxamic synthetase activity|positive regulation of L-glutamine synthetase activity|up regulation of glutamate-ammonia ligase activity|activation of glutamate-ammonia ligase activity|positive regulation of L-glutamate:ammonia ligase (ADP-forming)|up regulation of L-glutamate:ammonia ligase (ADP-forming)|positive regulation of glutamylhydroxamic synthetase activity|up-regulation of glutamine synthetase activity|up-regulation of L-glutamine synthetase activity|up regulation of glutamylhydroxamic synthetase activity|up-regulation of glutamate-ammonia ligase activity|upregulation of L-glutamate:ammonia ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_1905480 GO:2000852 biolink:BiologicalProcess regulation of corticosterone secretion Any process that modulates the frequency, rate or extent of corticosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000852 NCBITaxon:1502711 biolink:OrganismalEntity Erythranthe go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1502711 GO:1905481 biolink:BiologicalProcess obsolete cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic DNA replication checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_1905481 GO:2000853 biolink:BiologicalProcess negative regulation of corticosterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000853 GO:1905482 biolink:BiologicalProcess obsolete cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint OBSOLETE. Any cytoplasmic sequestering of protein that is involved in G2 DNA damage checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_1905482 GO:2000854 biolink:BiologicalProcess positive regulation of corticosterone secretion Any process that activates or increases the frequency, rate or extent of corticosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000854 GO:1905483 biolink:BiologicalProcess regulation of motor neuron migration Any process that modulates the frequency, rate or extent of motor neuron migration. go-plus.json http://purl.obolibrary.org/obo/GO_1905483 GO:2000855 biolink:BiologicalProcess regulation of mineralocorticoid secretion Any process that modulates the frequency, rate or extent of mineralocorticoid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000855 GO:1905484 biolink:BiologicalProcess negative regulation of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. go-plus.json down-regulation of motor neuron migration|downregulation of motor neuron migration|down regulation of motor neuron migration|inhibition of motor neuron migration http://purl.obolibrary.org/obo/GO_1905484 GO:2000856 biolink:BiologicalProcess negative regulation of mineralocorticoid secretion Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000856 GO:1905485 biolink:BiologicalProcess positive regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of motor neuron migration. go-plus.json up regulation of motor neuron migration|upregulation of motor neuron migration|activation of motor neuron migration|up-regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905485 GO:2000857 biolink:BiologicalProcess positive regulation of mineralocorticoid secretion Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000857 GO:1905486 biolink:BiologicalProcess regulation of anterior/posterior axon guidance Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance. go-plus.json regulation of anterior-posterior axon guidance|regulation of anterior/posterior axon pathfinding http://purl.obolibrary.org/obo/GO_1905486 GO:2000858 biolink:BiologicalProcess regulation of aldosterone secretion Any process that modulates the frequency, rate or extent of aldosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000858 GO:1905487 biolink:BiologicalProcess negative regulation of anterior/posterior axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance. go-plus.json negative regulation of anterior-posterior axon guidance|down-regulation of anterior-posterior axon guidance|down-regulation of anterior/posterior axon guidance|down regulation of anterior/posterior axon pathfinding|downregulation of anterior-posterior axon guidance|downregulation of anterior/posterior axon guidance|downregulation of anterior/posterior axon pathfinding|down regulation of anterior-posterior axon guidance|inhibition of anterior-posterior axon guidance|down regulation of anterior/posterior axon guidance|inhibition of anterior/posterior axon guidance|negative regulation of anterior/posterior axon pathfinding|down-regulation of anterior/posterior axon pathfinding|inhibition of anterior/posterior axon pathfinding http://purl.obolibrary.org/obo/GO_1905487 GO:2000859 biolink:BiologicalProcess negative regulation of aldosterone secretion Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000859 GO:1905477 biolink:BiologicalProcess positive regulation of protein localization to membrane Any process that activates or increases the frequency, rate or extent of protein localization to membrane. go-plus.json positive regulation of protein localization in membrane|up regulation of protein localization in membrane|upregulation of protein localization to membrane|upregulation of protein localisation in membrane|up-regulation of protein localization to membrane|activation of protein localization to membrane|upregulation of protein localization in membrane|activation of protein localisation in membrane|up-regulation of protein localisation in membrane|up-regulation of protein localization in membrane|activation of protein localization in membrane|up regulation of protein localization to membrane|positive regulation of protein localisation in membrane|up regulation of protein localisation in membrane http://purl.obolibrary.org/obo/GO_1905477 GO:1905478 biolink:BiologicalProcess regulation of glutamate-ammonia ligase activity Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity. go-plus.json regulation of L-glutamate:ammonia ligase (ADP-forming)|regulation of glutamylhydroxamic synthetase activity|regulation of glutamine synthetase activity|regulation of L-glutamine synthetase activity http://purl.obolibrary.org/obo/GO_1905478 GO:1905479 biolink:BiologicalProcess negative regulation of glutamate-ammonia ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity. go-plus.json downregulation of glutamate-ammonia ligase activity|negative regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of glutamine synthetase activity|negative regulation of glutamine synthetase activity|down-regulation of L-glutamine synthetase activity|negative regulation of L-glutamine synthetase activity|negative regulation of glutamylhydroxamic synthetase activity|down-regulation of glutamylhydroxamic synthetase activity|down-regulation of glutamate-ammonia ligase activity|downregulation of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamine synthetase activity|inhibition of L-glutamine synthetase activity|down regulation of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamate-ammonia ligase activity|downregulation of glutamylhydroxamic synthetase activity|inhibition of L-glutamate:ammonia ligase (ADP-forming)|down regulation of glutamylhydroxamic synthetase activity|inhibition of glutamylhydroxamic synthetase activity|down regulation of glutamine synthetase activity|down regulation of L-glutamine synthetase activity|downregulation of glutamine synthetase activity|down regulation of glutamate-ammonia ligase activity|downregulation of L-glutamine synthetase activity http://purl.obolibrary.org/obo/GO_1905479 CHEBI:16669 biolink:ChemicalSubstance 5-dehydro-2-deoxy-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16669 chebi_ph7_3 CHEBI:16667 biolink:ChemicalSubstance (4-hydroxyphenyl)acetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_16667 chebi_ph7_3 CHEBI:16668 biolink:ChemicalSubstance hypotaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16668 GO:2000850 biolink:BiologicalProcess negative regulation of glucocorticoid secretion Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000850 GO:2000851 biolink:BiologicalProcess positive regulation of glucocorticoid secretion Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_2000851 CHEBI:16666 biolink:ChemicalSubstance prephenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16666 GO:0075250 biolink:BiologicalProcess negative regulation of aeciospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium. go-plus.json http://purl.obolibrary.org/obo/GO_0075250 CHEBI:16663 biolink:ChemicalSubstance poly-cis-polyprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16663 CHEBI:16664 biolink:ChemicalSubstance albendazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16664 chebi_ph7_3 GO:0075251 biolink:BiologicalProcess uredospore formation The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus. go-plus.json urediniospore formation|ureidospore formation http://purl.obolibrary.org/obo/GO_0075251 GO:0075252 biolink:BiologicalProcess regulation of uredospore formation Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium. go-plus.json regulation of ureidospore formation http://purl.obolibrary.org/obo/GO_0075252 GO:0075253 biolink:BiologicalProcess positive regulation of uredospore formation Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium. go-plus.json positive regulation of ureidospore formation http://purl.obolibrary.org/obo/GO_0075253 GO:0075254 biolink:BiologicalProcess negative regulation of uredospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium. go-plus.json negative regulation of ureidospore formation http://purl.obolibrary.org/obo/GO_0075254 GO:0075255 biolink:BiologicalProcess teliospore formation The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0075255 CHEBI:16660 biolink:ChemicalSubstance (S)-4-hydroxymandelonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_16660 chebi_ph7_3 GO:0075256 biolink:BiologicalProcess regulation of teliospore formation Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0075256 GO:0075257 biolink:BiologicalProcess positive regulation of teliospore formation Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0075257 GO:0002225 biolink:BiologicalProcess positive regulation of antimicrobial peptide production Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production. go-plus.json up-regulation of antimicrobial peptide production|activation of antimicrobial peptide production|up regulation of antimicrobial peptide production|antimicrobial peptide induction|upregulation of antimicrobial peptide production|stimulation of antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002225 GO:0002226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002226 GO:0002227 biolink:BiologicalProcess innate immune response in mucosa Any process of the innate immune response that takes place in the mucosal tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0002227 GO:0002228 biolink:BiologicalProcess natural killer cell mediated immunity The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. go-plus.json NK cell mediated immunity http://purl.obolibrary.org/obo/GO_0002228 GO:0002221 biolink:BiologicalProcess pattern recognition receptor signaling pathway Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells. go-plus.json pathogen receptor signalling pathway|PAMP receptor signaling pathway|pathogen receptor signaling pathway|PRR signaling pathway http://purl.obolibrary.org/obo/GO_0002221 GO:0002222 biolink:BiologicalProcess stimulatory killer cell immunoglobulin-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation. go-plus.json stimulatory KIR signaling pathway|stimulatory killer cell immunoglobulin-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002222 CHEBI:145326 biolink:ChemicalSubstance 2,3-dehydroamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145326 GO:0002223 biolink:BiologicalProcess stimulatory C-type lectin receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation. go-plus.json stimulatory C-type lectin receptor signalling pathway|stimulatory Ly49 family receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002223 GO:0002224 biolink:BiologicalProcess toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go-plus.json toll-like receptor signalling pathway|TLR signaling pathway http://purl.obolibrary.org/obo/GO_0002224 GO:0002220 biolink:BiologicalProcess innate immune response activating cell surface receptor signaling pathway Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor. go-plus.json innate immune response activating cell surface receptor signalling pathway|activation of innate immune response by cell surface receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002220 GO:0016866 biolink:MolecularActivity intramolecular transferase activity Catalysis of the transfer of a functional group from one position to another within a single molecule. EC:5.4.-.- go-plus.json mutase activity|intramolecular transferase activity, transferring other groups http://purl.obolibrary.org/obo/GO_0016866 GO:0016867 biolink:MolecularActivity intramolecular transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one position to another within a single molecule. EC:5.4.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016867 GO:0016868 biolink:MolecularActivity intramolecular transferase activity, phosphotransferases Catalysis of the transfer of a phosphate group from one position to another within a single molecule. EC:5.4.2.- go-plus.json phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers|phosphomutase activity http://purl.obolibrary.org/obo/GO_0016868 GO:0016869 biolink:MolecularActivity intramolecular transferase activity, transferring amino groups Catalysis of the transfer of an amino group from one position to another within a single molecule. EC:5.4.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016869 GO:0016862 biolink:MolecularActivity intramolecular oxidoreductase activity, interconverting keto- and enol-groups Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears. EC:5.3.2.- go-plus.json intramolecular isomerase activity, interconverting keto- and enol-groups http://purl.obolibrary.org/obo/GO_0016862 GO:0016863 biolink:MolecularActivity intramolecular oxidoreductase activity, transposing C=C bonds Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears. EC:5.3.3.- go-plus.json intramolecular isomerase activity, transposing C=C bonds http://purl.obolibrary.org/obo/GO_0016863 GO:0016864 biolink:MolecularActivity intramolecular oxidoreductase activity, transposing S-S bonds Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears. EC:5.3.4.- go-plus.json intramolecular isomerase activity, transposing S-S bonds http://purl.obolibrary.org/obo/GO_0016864 GO:0016865 biolink:MolecularActivity obsolete intramolecular oxidoreductase activity, other intramolecular oxidoreductases OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized. go-plus.json intramolecular oxidoreductase activity, other intramolecular oxidoreductases|intramolecular isomerase activity, other intramolecular oxidoreductases http://purl.obolibrary.org/obo/GO_0016865 CHEBI:90553 biolink:ChemicalSubstance 1-dihexosyl-2,3-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90553 chebi_ph7_3 GO:0016860 biolink:MolecularActivity intramolecular oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears. EC:5.3.-.-|Reactome:R-HSA-109998 go-plus.json intramolecular isomerase activity|intramolecular oxidoreductase activity, other intramolecular oxidoreductases http://purl.obolibrary.org/obo/GO_0016860 GO:0016861 biolink:MolecularActivity intramolecular oxidoreductase activity, interconverting aldoses and ketoses Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears. EC:5.3.1.- go-plus.json intramolecular isomerase activity, interconverting aldoses and ketoses http://purl.obolibrary.org/obo/GO_0016861 GO:0002229 biolink:BiologicalProcess defense response to oomycetes Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0002229 CHEBI:90550 biolink:ChemicalSubstance monohexosyldiglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_90550 chebi_ph7_3 CHEBI:90551 biolink:ChemicalSubstance monohexosyldiradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90551 chebi_ph7_3 GO:0002236 biolink:BiologicalProcess detection of misfolded protein The series of events in which a misfolded protein stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0002236 GO:0002237 biolink:BiologicalProcess response to molecule of bacterial origin Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin. go-plus.json response to bacterium associated molecule|response to bacteria associated molecule|response to bacterial associated molecule http://purl.obolibrary.org/obo/GO_0002237 GO:0002238 biolink:BiologicalProcess response to molecule of fungal origin Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide. go-plus.json response to fungus associated molecule http://purl.obolibrary.org/obo/GO_0002238 GO:0002239 biolink:BiologicalProcess response to oomycetes Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0002239 GO:0002232 biolink:BiologicalProcess leukocyte chemotaxis involved in inflammatory response The movement of an immune cell in response to an external stimulus contributing to an inflammatory response. go-plus.json immune cell chemotaxis during inflammatory response|leukocyte chemotaxis during inflammatory response|leucocyte chemotaxis during inflammatory response http://purl.obolibrary.org/obo/GO_0002232 GO:0002233 biolink:BiologicalProcess leukocyte chemotaxis involved in immune response The movement of an immune cell in response to an external stimulus a part of an immune response. go-plus.json leucocyte chemotaxis during immune response|immune cell chemotaxis during immune response http://purl.obolibrary.org/obo/GO_0002233 GO:0002234 biolink:BiologicalProcess detection of endoplasmic reticulum overloading The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal. go-plus.json detection of ER overloading http://purl.obolibrary.org/obo/GO_0002234 GO:0002235 biolink:BiologicalProcess detection of unfolded protein The series of events in which an unfolded protein stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0002235 GO:0002230 biolink:BiologicalProcess positive regulation of defense response to virus by host Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication. go-plus.json up regulation of antiviral response by host|upregulation of antiviral response by host|stimulation of antiviral response by host|up-regulation of antiviral response by host|positive regulation of antiviral response by host|activation of antiviral response by host http://purl.obolibrary.org/obo/GO_0002230 GO:0002231 biolink:BiologicalProcess detection of oomycetes The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0002231 GO:0016877 biolink:MolecularActivity ligase activity, forming carbon-sulfur bonds Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.2.-.- go-plus.json ligase activity, forming carbon-sulphur bonds http://purl.obolibrary.org/obo/GO_0016877 GO:0016878 biolink:MolecularActivity acid-thiol ligase activity Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016878 GO:0016879 biolink:MolecularActivity ligase activity, forming carbon-nitrogen bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.3.-.- go-plus.json other carbon-nitrogen ligase activity http://purl.obolibrary.org/obo/GO_0016879 GO:0016873 biolink:MolecularActivity obsolete other isomerase activity OBSOLETE. A grouping term for isomerases that cannot be more accurately categorized. go-plus.json other isomerase activity http://purl.obolibrary.org/obo/GO_0016873 CHEBI:90546 biolink:ChemicalSubstance medium-chain fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90546 chebi_ph7_3 GO:0016874 biolink:MolecularActivity ligase activity Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. EC:6.-.-.- go-plus.json synthetase activity http://purl.obolibrary.org/obo/GO_0016874 goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic GO:0016875 biolink:MolecularActivity ligase activity, forming carbon-oxygen bonds Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.1.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016875 GO:0016876 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016876 CHEBI:90549 biolink:ChemicalSubstance 1-monohexosyl-2,3-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90549 chebi_ph7_3 GO:0016870 biolink:MolecularActivity obsolete intramolecular transferase activity, transferring other groups OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized. go-plus.json intramolecular transferase activity, transferring other groups http://purl.obolibrary.org/obo/GO_0016870 GO:0016871 biolink:MolecularActivity cycloartenol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol. RHEA:21308|MetaCyc:CYCLOARTENOL-SYNTHASE-RXN|KEGG_REACTION:R03200|EC:5.4.99.8 go-plus.json 2,3-epoxysqualene cycloartenol-cyclase activity|2,3-epoxysqualene--cycloartenol cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)|2,3-oxidosqualene-cycloartenol cyclase activity|squalene-2,3-epoxide-cycloartenol cyclase activity|oxidosqualene:cycloartenol cyclase activity http://purl.obolibrary.org/obo/GO_0016871 GO:0016872 biolink:MolecularActivity intramolecular lyase activity The catalysis of certain rearrangements of a molecule to break or form a ring. EC:5.5.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016872 GO:0002203 biolink:BiologicalProcess proteolysis by cytosolic proteases associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002203 GO:0002204 biolink:BiologicalProcess somatic recombination of immunoglobulin genes involved in immune response The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response. go-plus.json somatic recombination of antibody genes during immune response|somatic recombination of immunoglobulin genes during immune response http://purl.obolibrary.org/obo/GO_0002204 GO:0002205 biolink:BiologicalProcess somatic hypermutation of immunoglobulin genes involved in immune response Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response. go-plus.json somatic hypermutation of antibody genes during immune response|somatic hypermutation of immunoglobulin genes during immune response http://purl.obolibrary.org/obo/GO_0002205 GO:0002206 biolink:BiologicalProcess gene conversion of immunoglobulin genes The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion. go-plus.json gene conversion of antibody genes http://purl.obolibrary.org/obo/GO_0002206 GO:0002200 biolink:BiologicalProcess somatic diversification of immune receptors The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. go-plus.json http://purl.obolibrary.org/obo/GO_0002200 GO:0002201 biolink:BiologicalProcess somatic diversification of DSCAM-based immune receptors The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects. go-plus.json http://purl.obolibrary.org/obo/GO_0002201 GO:0002202 biolink:BiologicalProcess somatic diversification of variable lymphocyte receptors of jawless fish The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish. go-plus.json http://purl.obolibrary.org/obo/GO_0002202 GO:0016848 biolink:MolecularActivity carbon-halide lyase activity Catalysis of the breakage of a bond between carbon and any halogen atom. EC:4.5.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016848 GO:0016849 biolink:MolecularActivity phosphorus-oxygen lyase activity Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. EC:4.6.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016849 GO:0016844 biolink:MolecularActivity strictosidine synthase activity Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine. RHEA:15013|EC:4.3.3.2|MetaCyc:STRICTOSIDINE-SYNTHASE-RXN|KEGG_REACTION:R03738 go-plus.json 3-alpha(S)-strictosidine tryptamine-lyase activity|strictosidine synthetase activity|STR activity|3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming) http://purl.obolibrary.org/obo/GO_0016844 GO:0016845 biolink:MolecularActivity obsolete other carbon-nitrogen lyase activity OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases. go-plus.json other carbon-nitrogen lyase activity http://purl.obolibrary.org/obo/GO_0016845 GO:0016846 biolink:MolecularActivity carbon-sulfur lyase activity Catalysis of the elimination of hydrogen sulfide or substituted H2S. EC:4.4.-.-|Reactome:R-HSA-1614567 go-plus.json carbon-sulphur lyase activity http://purl.obolibrary.org/obo/GO_0016846 GO:0016847 biolink:MolecularActivity 1-aminocyclopropane-1-carboxylate synthase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+). KEGG_REACTION:R00179|MetaCyc:4.4.1.14-RXN|RHEA:21744|EC:4.4.1.14 go-plus.json L-vinylglycine deaminase activity|1-aminocyclopropane-1-carboxylic acid synthase activity|aminocyclopropanecarboxylic acid synthase activity|1-aminocyclopropane-1-carboxylate synthetase activity|S-adenosyl-L-methionine methylthioadenosine-lyase activity|L-VG deaminase activity|S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)|aminocyclopropanecarboxylate synthase activity|ACC synthase activity|1-aminocyclopropanecarboxylate synthase activity http://purl.obolibrary.org/obo/GO_0016847 GO:0016840 biolink:MolecularActivity carbon-nitrogen lyase activity Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99). EC:4.3.-.- go-plus.json other carbon-nitrogen lyase activity http://purl.obolibrary.org/obo/GO_0016840 GO:0016841 biolink:MolecularActivity ammonia-lyase activity Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate. EC:4.3.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016841 GO:0016842 biolink:MolecularActivity amidine-lyase activity Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate. EC:4.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016842 GO:0016843 biolink:MolecularActivity amine-lyase activity Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate. EC:4.3.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016843 CHEBI:90575 biolink:ChemicalSubstance dihexosyldiglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_90575 chebi_ph7_3 CHEBI:90576 biolink:ChemicalSubstance dihexosyldiradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90576 chebi_ph7_3 CHEBI:90577 biolink:ChemicalSubstance 1-(9S,13S,12-oxophytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90577 chebi_ph7_3 CHEBI:90578 biolink:ChemicalSubstance 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90578 chebi_ph7_3 GO:0002207 biolink:BiologicalProcess gene conversion of immunoglobulin genes involved in immune response The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response. go-plus.json gene conversion of antibody genes during immune response|gene conversion of immunoglobulin genes during immune response http://purl.obolibrary.org/obo/GO_0002207 GO:0002208 biolink:BiologicalProcess somatic diversification of immunoglobulins involved in immune response The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response. go-plus.json somatic diversification of immunoglobulins during immune response|somatic diversification of antibodies during immune response http://purl.obolibrary.org/obo/GO_0002208 GO:0002209 biolink:BiologicalProcess behavioral defense response A behavioral response seeking to protect an organism from an a perceived external threat to that organism. go-plus.json behavioural defense response http://purl.obolibrary.org/obo/GO_0002209 GO:0002214 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002214 GO:0002215 biolink:BiologicalProcess defense response to nematode A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. go-plus.json physiological defense response to nematode http://purl.obolibrary.org/obo/GO_0002215 GO:0002216 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002216 GO:0002217 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002217 GO:0002210 biolink:BiologicalProcess behavioral response to wounding A behavioral response resulting from wounding. go-plus.json behavioural response to wounding http://purl.obolibrary.org/obo/GO_0002210 GO:0002211 biolink:BiologicalProcess behavioral defense response to insect A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism. go-plus.json behavioural defense response to insect http://purl.obolibrary.org/obo/GO_0002211 GO:0002212 biolink:BiologicalProcess behavioral defense response to nematode A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism. go-plus.json behavioural defense response to nematode http://purl.obolibrary.org/obo/GO_0002212 GO:0002213 biolink:BiologicalProcess defense response to insect A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. go-plus.json physiological defense response to insect http://purl.obolibrary.org/obo/GO_0002213 CHEBI:41595 biolink:ChemicalSubstance (+)-germacrene A go-plus.json http://purl.obolibrary.org/obo/CHEBI_41595 chebi_ph7_3 GO:0016859 biolink:MolecularActivity cis-trans isomerase activity Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. EC:5.2.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016859 GO:0016855 biolink:MolecularActivity racemase and epimerase activity, acting on amino acids and derivatives Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid. EC:5.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016855 GO:0016856 biolink:MolecularActivity racemase and epimerase activity, acting on hydroxy acids and derivatives Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule. EC:5.1.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016856 GO:0016857 biolink:MolecularActivity racemase and epimerase activity, acting on carbohydrates and derivatives Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule. EC:5.1.3.-|Reactome:R-HSA-6787677 go-plus.json http://purl.obolibrary.org/obo/GO_0016857 GO:0016858 biolink:MolecularActivity obsolete racemase and epimerase activity, acting on other compounds OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives. go-plus.json racemase and epimerase activity, acting on other compounds http://purl.obolibrary.org/obo/GO_0016858 GO:0016851 biolink:MolecularActivity magnesium chelatase activity Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate. KEGG_REACTION:R03877|RHEA:13961|EC:6.6.1.1|MetaCyc:RXN1F-20 go-plus.json magnesium-chelatase activity|Mg-chelatase activity|magnesium-protoporphyrin chelatase activity|Mg-protoporphyrin IX magnesium-lyase activity|magnesium-protoporphyrin IX chelatase activity|protoporphyrin IX magnesium-chelatase activity|Mg-protoporphyrin IX magnesio-lyase activity|Mg-protoporphyrin IX chelatase activity|protoporphyrin IX Mg-chelatase activity http://purl.obolibrary.org/obo/GO_0016851 GO:0016852 biolink:MolecularActivity sirohydrochlorin cobaltochelatase activity Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+. MetaCyc:4.99.1.3-RXN|RHEA:15893|EC:4.99.1.3 go-plus.json anaerobic cobalt chelatase activity|CbiXS|cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)|CbiK|sirohydrochlorin cobalt-lyase activity|CbiX http://purl.obolibrary.org/obo/GO_0016852 GO:0016853 biolink:MolecularActivity isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. EC:5.-.-.-|Reactome:R-HSA-6787623 go-plus.json other isomerase activity http://purl.obolibrary.org/obo/GO_0016853 goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic GO:0016854 biolink:MolecularActivity racemase and epimerase activity Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule. EC:5.1.-.- go-plus.json racemase and epimerase activity, acting on other compounds http://purl.obolibrary.org/obo/GO_0016854 GO:0016850 biolink:MolecularActivity obsolete other lyase activity OBSOLETE. A grouping term for lyases that cannot be more accurately categorized. go-plus.json other lyase activity http://purl.obolibrary.org/obo/GO_0016850 GO:0002218 biolink:BiologicalProcess activation of innate immune response Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species. go-plus.json http://purl.obolibrary.org/obo/GO_0002218 GO:0002219 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002219 CHEBI:41582 biolink:ChemicalSubstance D-pipecolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41582 GO:0016826 biolink:MolecularActivity hydrolase activity, acting on acid sulfur-nitrogen bonds Catalysis of the hydrolysis of any acid sulfur-nitrogen bond. EC:3.10.-.- go-plus.json hydrolase activity, acting on acid sulphur-nitrogen bonds http://purl.obolibrary.org/obo/GO_0016826 GO:0016827 biolink:MolecularActivity hydrolase activity, acting on acid carbon-phosphorus bonds Catalysis of the hydrolysis of any acid carbon-phosphorus bond. EC:3.11.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016827 GO:0016828 biolink:MolecularActivity hydrolase activity, acting on acid sulfur-sulfur bonds Catalysis of the hydrolysis of any acid sulfur-sulfur bond. EC:3.12.-.- go-plus.json hydrolase activity, acting on acid sulphur-sulphur bonds http://purl.obolibrary.org/obo/GO_0016828 GO:0016829 biolink:MolecularActivity lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. Reactome:R-HSA-6782895|Reactome:R-HSA-5696408|EC:4.-.-.- go-plus.json other lyase activity http://purl.obolibrary.org/obo/GO_0016829 goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic GO:0016822 biolink:MolecularActivity hydrolase activity, acting on acid carbon-carbon bonds Catalysis of the hydrolysis of any acid carbon-carbon bond. EC:3.7.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016822 GO:0016823 biolink:MolecularActivity hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group. EC:3.7.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016823 GO:0016824 biolink:MolecularActivity hydrolase activity, acting on acid halide bonds Catalysis of the hydrolysis of any acid halide bond. EC:3.8.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016824 GO:0016825 biolink:MolecularActivity hydrolase activity, acting on acid phosphorus-nitrogen bonds Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond. EC:3.9.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016825 GO:0016820 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016820 GO:0016821 biolink:MolecularActivity obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement OBSOLETE. (Was not defined before being made obsolete). go-plus.json hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement http://purl.obolibrary.org/obo/GO_0016821 CHEBI:90598 biolink:ChemicalSubstance L-isoaspartate alpha-methyl ester residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90598 chebi_ph7_3 CHEBI:90595 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_90595 CHEBI:90596 biolink:ChemicalSubstance L-beta-isoaspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90596 chebi_ph7_3 GO:0051203 biolink:BiologicalProcess peptidyl-aspartic acid reduction to form L-aspartyl aldehyde The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein. RESID:AA0373 go-plus.json peptidyl-aspartic acid reduction to form L-aspartate-beta-semialdehyde|peptidyl-aspartic acid reduction to form L-beta-formylalanine http://purl.obolibrary.org/obo/GO_0051203 GO:0051204 biolink:BiologicalProcess protein insertion into mitochondrial membrane The process that results in the incorporation of a protein into a mitochondrial membrane. go-plus.json integral mitochondrial membrane protein localization|integral mitochondrial membrane protein positioning|protein-mitochondrion membrane insertion|protein insertion into mitochondrion membrane|localization of protein in mitochondrial membrane|positioning of protein in mitochondrial membrane|protein-mitochondrial membrane insertion http://purl.obolibrary.org/obo/GO_0051204 GO:0051201 biolink:BiologicalProcess negative regulation of prosthetic group metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. go-plus.json downregulation of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolic process|down regulation of prosthetic group metabolic process|inhibition of prosthetic group metabolic process|negative regulation of prosthetic group metabolism|down-regulation of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolism http://purl.obolibrary.org/obo/GO_0051201 GO:0051202 biolink:BiologicalProcess phytochromobilin metabolic process The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity. go-plus.json phytochromobilin metabolism http://purl.obolibrary.org/obo/GO_0051202 GO:0051207 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051207 GO:0051208 biolink:BiologicalProcess sequestering of calcium ion The process of binding or confining calcium ions such that they are separated from other components of a biological system. go-plus.json retention of calcium ion (Ca2+)|calcium ion storage activity|storage of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) transport|calcium ion (Ca2+) retention|sequestration of calcium ion (Ca2+)|calcium ion (Ca2+) storage|calcium ion (Ca2+) sequestering|calcium ion (Ca2+) sequestration|sequestering of calcium ion (Ca2+) http://purl.obolibrary.org/obo/GO_0051208 GO:0051205 biolink:BiologicalProcess protein insertion into membrane The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers. go-plus.json integral membrane protein localization|membrane protein positioning|protein-membrane insertion|integral membrane protein positioning|membrane protein localization http://purl.obolibrary.org/obo/GO_0051205 GO:0051206 biolink:BiologicalProcess silicate metabolic process The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates. go-plus.json silicate metabolism http://purl.obolibrary.org/obo/GO_0051206 GO:0051209 biolink:BiologicalProcess release of sequestered calcium ion into cytosol The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment. go-plus.json calcium ion (Ca2+) mobilization|release of stored calcium ion (Ca2+) into cytoplasm|release of sequestered calcium ion (Ca2+)|release of stored calcium ion (Ca2+) into cytosol|release of stored calcium ion (Ca2+)|cytoplasmic release of stored calcium ion (Ca2+)|calcium mobilization|cytosolic release of stored calcium ion (Ca2+)|cytoplasmic release of sequestered calcium ion (Ca2+)|release of sequestered calcium ion into cytoplasm|cytosolic release of sequestered calcium ion (Ca2+) http://purl.obolibrary.org/obo/GO_0051209 GO:0016837 biolink:MolecularActivity carbon-oxygen lyase activity, acting on polysaccharides Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide. EC:4.2.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016837 GO:0016838 biolink:MolecularActivity carbon-oxygen lyase activity, acting on phosphates Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate. EC:4.2.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016838 GO:0016839 biolink:MolecularActivity obsolete other carbon-oxygen lyase activity OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases. go-plus.json other carbon-oxygen lyase activity http://purl.obolibrary.org/obo/GO_0016839 GO:0016833 biolink:MolecularActivity oxo-acid-lyase activity Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid. EC:4.1.3.- go-plus.json oxoacid lyase activity|oxo-acid lyase activity http://purl.obolibrary.org/obo/GO_0016833 GO:0016834 biolink:MolecularActivity obsolete other carbon-carbon lyase activity OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized. go-plus.json other carbon-carbon lyase activity http://purl.obolibrary.org/obo/GO_0016834 GO:0016835 biolink:MolecularActivity carbon-oxygen lyase activity Catalysis of the breakage of a carbon-oxygen bond. EC:4.2.-.- go-plus.json other carbon-oxygen lyase activity http://purl.obolibrary.org/obo/GO_0016835 GO:0016836 biolink:MolecularActivity hydro-lyase activity Catalysis of the cleavage of a carbon-oxygen bond by elimination of water. EC:4.2.1.-|Reactome:R-HSA-9014627 go-plus.json http://purl.obolibrary.org/obo/GO_0016836 GO:0016830 biolink:MolecularActivity carbon-carbon lyase activity Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. EC:4.1.-.-|Reactome:R-HSA-389611 go-plus.json other carbon-carbon lyase activity http://purl.obolibrary.org/obo/GO_0016830 GO:0016831 biolink:MolecularActivity carboxy-lyase activity Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. Reactome:R-HSA-6814165|Reactome:R-HSA-6787757|Reactome:R-HSA-71223|EC:4.1.1.- go-plus.json decarboxylase activity http://purl.obolibrary.org/obo/GO_0016831 GO:0016832 biolink:MolecularActivity aldehyde-lyase activity Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone. EC:4.1.2.- go-plus.json aldolase activity http://purl.obolibrary.org/obo/GO_0016832 CHEBI:90582 biolink:ChemicalSubstance hexadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90582 chebi_ph7_3 GO:0051200 biolink:BiologicalProcess positive regulation of prosthetic group metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. go-plus.json positive regulation of coenzyme and prosthetic group metabolism|upregulation of prosthetic group metabolic process|stimulation of prosthetic group metabolic process|positive regulation of prosthetic group metabolism|up-regulation of prosthetic group metabolic process|activation of prosthetic group metabolic process|positive regulation of coenzyme and prosthetic group metabolic process|up regulation of prosthetic group metabolic process http://purl.obolibrary.org/obo/GO_0051200 GO:0051214 biolink:BiologicalProcess RNAi-mediated antiviral immunity against RNA virus Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing. In plants, DCL4 is the primary Dicer to detect RNA viruses. go-plus.json RNA virus induced gene silencing|RNA VIGS|RNA virus-induced gene silencing http://purl.obolibrary.org/obo/GO_0051214 GO:0051215 biolink:BiologicalProcess RNAi-mediated antiviral immunity against DNA virus Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing. In plants, DCL3 is the primary Dicer to detect DNA viruses. go-plus.json DNA VIGS|DNA virus-induced gene silencing|DNA virus induced gene silencing http://purl.obolibrary.org/obo/GO_0051215 GO:0051212 biolink:MolecularActivity vanadium ion binding Binding to a vanadium ion (V). go-plus.json V ion binding http://purl.obolibrary.org/obo/GO_0051212 GO:0051213 biolink:MolecularActivity dioxygenase activity Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products. Reactome:R-HSA-112125|Reactome:R-HSA-112121|Reactome:R-HSA-112124|Reactome:R-HSA-112120 go-plus.json http://purl.obolibrary.org/obo/GO_0051213 goslim_pir GO:0051218 biolink:BiologicalProcess tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide). RESID:AA02376 go-plus.json http://purl.obolibrary.org/obo/GO_0051218 GO:0051219 biolink:MolecularActivity phosphoprotein binding Binding to a phosphorylated protein. go-plus.json phosphorylated protein binding http://purl.obolibrary.org/obo/GO_0051219 goslim_chembl GO:0051216 biolink:BiologicalProcess cartilage development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. Wikipedia:Chondrogenesis go-plus.json chondrogenesis|cartilage organ development|cartilage biogenesis|cartilage element development|cartilage biosynthesis|cartilage formation http://purl.obolibrary.org/obo/GO_0051216 GO:0051217 biolink:BiologicalProcess molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide) The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide). RESID:AA0375 go-plus.json http://purl.obolibrary.org/obo/GO_0051217 GO:0016808 biolink:MolecularActivity obsolete proprotein convertase activity OBSOLETE. Was not defined before being made obsolete. go-plus.json proprotein convertase activity http://purl.obolibrary.org/obo/GO_0016808 GO:0016809 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016809 GO:0016804 biolink:MolecularActivity obsolete prolyl aminopeptidase activity OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide. go-plus.json proline aminopeptidase|cytosol aminopeptidase V|prolyl aminopeptidase activity|Pro-X aminopeptidase activity|proline iminopeptidase activity http://purl.obolibrary.org/obo/GO_0016804 GO:0016805 biolink:MolecularActivity dipeptidase activity Catalysis of the hydrolysis of a dipeptide. EC:3.4.13.-|Reactome:R-HSA-9026771|MetaCyc:3.4.13.18-RXN|Reactome:R-HSA-5433067|EC:3.4.13.18|MetaCyc:3.4.13.21-RXN|EC:3.4.13.21|Reactome:R-HSA-266012|Reactome:R-HSA-5693783 go-plus.json cytosolic dipeptidase activity http://purl.obolibrary.org/obo/GO_0016805 GO:0016806 biolink:MolecularActivity obsolete dipeptidyl-peptidase and tripeptidyl-peptidase activity OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain. EC:3.4.14.- go-plus.json dipeptidyl-peptidase and tripeptidyl-peptidase activity http://purl.obolibrary.org/obo/GO_0016806 GO:0016807 biolink:MolecularActivity cysteine-type carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. MetaCyc:3.4.18.1-RXN|EC:3.4.18.- go-plus.json http://purl.obolibrary.org/obo/GO_0016807 GO:0016800 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016800 GO:0016801 biolink:MolecularActivity hydrolase activity, acting on ether bonds Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively. EC:3.3.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016801 GO:0016802 biolink:MolecularActivity trialkylsulfonium hydrolase activity Catalysis of the hydrolysis of a thioether bond, -S-. EC:3.3.1.- go-plus.json trialkylsulphonium hydrolase activity|thioether hydrolase activity http://purl.obolibrary.org/obo/GO_0016802 GO:0016803 biolink:MolecularActivity ether hydrolase activity Catalysis of the hydrolysis of an ether bond, -O-. Reactome:R-HSA-8874435|EC:3.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016803 GO:0051210 biolink:BiologicalProcess isotropic cell growth The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth. go-plus.json uniform cell growth http://purl.obolibrary.org/obo/GO_0051210 GO:0051211 biolink:BiologicalProcess anisotropic cell growth The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell. go-plus.json non-isotropic cell growth http://purl.obolibrary.org/obo/GO_0051211 UBERON:0008522 biolink:AnatomicalEntity nasal muscle Any muscle organ that is part of an nose. go-plus.json muscle of nose http://purl.obolibrary.org/obo/UBERON_0008522 GO:0051225 biolink:BiologicalProcess spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. go-plus.json bipolar spindle biosynthesis|spindle biosynthesis|spindle formation|bipolar spindle formation http://purl.obolibrary.org/obo/GO_0051225 GO:0051226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051226 GO:0051223 biolink:BiologicalProcess regulation of protein transport Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051223 GO:0051224 biolink:BiologicalProcess negative regulation of protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json downregulation of protein transport|down-regulation of protein transport|inhibition of protein transport|down regulation of protein transport http://purl.obolibrary.org/obo/GO_0051224 GO:0051229 biolink:BiologicalProcess meiotic spindle disassembly The controlled breakdown of the spindle during a meiotic cell cycle. go-plus.json meiotic spindle degradation|spindle disassembly during meiosis|meiotic spindle breakdown|spindle breakdown during meiosis|meiotic spindle catabolism|spindle degradation during meiosis http://purl.obolibrary.org/obo/GO_0051229 GO:0051227 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051227 GO:0051228 biolink:BiologicalProcess mitotic spindle disassembly The controlled breakdown of the spindle during a mitotic cell cycle. go-plus.json spindle disassembly during mitosis|mitotic spindle degradation|mitotic spindle breakdown|spindle breakdown during mitosis|spindle degradation during mitosis|mitotic spindle catabolism http://purl.obolibrary.org/obo/GO_0051228 GO:0016819 biolink:MolecularActivity hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-. EC:3.6.2.- go-plus.json hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides http://purl.obolibrary.org/obo/GO_0016819 GO:0016815 biolink:MolecularActivity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN. EC:3.5.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0016815 GO:0016816 biolink:MolecularActivity obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles. go-plus.json hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds http://purl.obolibrary.org/obo/GO_0016816 CHEBI:41550 biolink:ChemicalSubstance fluoroform go-plus.json http://purl.obolibrary.org/obo/CHEBI_41550 chebi_ph7_3 GO:0016817 biolink:MolecularActivity hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride. EC:3.6.-.- go-plus.json hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement http://purl.obolibrary.org/obo/GO_0016817 GO:0016818 biolink:MolecularActivity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. EC:3.6.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016818 GO:0016811 biolink:MolecularActivity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. EC:3.5.1.-|Reactome:R-HSA-9673053|Reactome:R-HSA-9673054 go-plus.json http://purl.obolibrary.org/obo/GO_0016811 GO:0016812 biolink:MolecularActivity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide. EC:3.5.2.-|Reactome:R-HSA-70906 go-plus.json http://purl.obolibrary.org/obo/GO_0016812 GO:0016813 biolink:MolecularActivity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. EC:3.5.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016813 GO:0016814 biolink:MolecularActivity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2. EC:3.5.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0016814 GO:0016810 biolink:MolecularActivity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. EC:3.5.-.-|Reactome:R-HSA-6803753 go-plus.json hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds http://purl.obolibrary.org/obo/GO_0016810 goslim_generic|goslim_chembl|goslim_drosophila GO:0051221 biolink:BiologicalProcess tungsten incorporation into metallo-sulfur cluster The incorporation of tungsten into a metallo-sulfur cluster. go-plus.json tungsten incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0051221 GO:0051222 biolink:BiologicalProcess positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of protein transport|activation of protein transport|stimulation of protein transport|up-regulation of protein transport|upregulation of protein transport http://purl.obolibrary.org/obo/GO_0051222 GO:0051220 biolink:BiologicalProcess cytoplasmic sequestering of protein The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell. go-plus.json cytoplasmic storage of protein|retention of protein in cytoplasm|storage of protein in cytoplasm|cytoplasmic retention of protein|maintenance of protein location in cytoplasm|sequestration of protein in cytoplasm|cytoplasmic sequestration of protein|sequestering of protein in cytoplasm http://purl.obolibrary.org/obo/GO_0051220 NCBITaxon:28901 biolink:OrganismalEntity Salmonella enterica go-plus.json Salmonella enterica ser. choleraesuis|Salmonella choleraesuis|Salmonella cholerae-suis|Bacillus cholerae-suis http://purl.obolibrary.org/obo/NCBITaxon_28901 CHEBI:145394 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145394 chebi_ph7_3 CHEBI:145397 biolink:ChemicalSubstance 1-oleoyl-2-acyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_145397 chebi_ph7_3 GO:0002287 biolink:BiologicalProcess alpha-beta T cell activation involved in immune response The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. go-plus.json alpha-beta T lymphocyte activation during immune response|alpha-beta T-cell activation during immune response|alpha-beta T-lymphocyte activation during immune response|alpha-beta T cell activation during immune response http://purl.obolibrary.org/obo/GO_0002287 GO:0002288 biolink:BiologicalProcess NK T cell activation involved in immune response The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. go-plus.json natural killer T lymphocyte activation during immune response|NK T-cell activation during immune response|NK T-lymphocyte activation during immune response|natural killer T-cell activation during immune response|NK T cell activation during immune response|natural killer T-lymphocyte activation during immune response|NK T lymphocyte activation during immune response http://purl.obolibrary.org/obo/GO_0002288 GO:0002289 biolink:BiologicalProcess NK T cell proliferation involved in immune response The expansion of a NK T cell population by cell division as part of an immune response. go-plus.json NK T-cell proliferation during immune response|natural killer T lymphocyte proliferation during immune response|NK T cell proliferation during immune response|NK T lymphocyte proliferation during immune response|natural killer T-lymphocyte proliferation during immune response|natural killer T-cell proliferation during immune response|NK T-lymphocyte proliferation during immune response http://purl.obolibrary.org/obo/GO_0002289 GO:0002283 biolink:BiologicalProcess neutrophil activation involved in immune response The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json neutrophil activation during immune response http://purl.obolibrary.org/obo/GO_0002283 GO:0002284 biolink:BiologicalProcess myeloid dendritic cell differentiation involved in immune response The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response. go-plus.json myeloid dendritic cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0002284 GO:0002285 biolink:BiologicalProcess lymphocyte activation involved in immune response A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json lymphocyte activation during immune response http://purl.obolibrary.org/obo/GO_0002285 GO:0002286 biolink:BiologicalProcess T cell activation involved in immune response The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. go-plus.json T lymphocyte activation during immune response|T-cell activation during immune response|T-lymphocyte activation during immune response|T cell activation during immune response http://purl.obolibrary.org/obo/GO_0002286 GO:0099191 biolink:BiologicalProcess trans-synaptic signaling by BDNF Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft. go-plus.json trans-synaptic signaling by brain-derived neurotrophic factor http://purl.obolibrary.org/obo/GO_0099191 goslim_synapse OBO:chebi#is_substituent_group_from biolink:OntologyClass is substituent group from go-plus.json http://purl.obolibrary.org/obo/chebi#is_substituent_group_from GO:0099192 biolink:CellularComponent cerebellar Golgi cell to granule cell synapse A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell. go-plus.json http://purl.obolibrary.org/obo/GO_0099192 goslim_synapse GO:0002280 biolink:BiologicalProcess monocyte activation involved in immune response The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json monocyte activation during immune response http://purl.obolibrary.org/obo/GO_0002280 GO:0002281 biolink:BiologicalProcess macrophage activation involved in immune response A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json macrophage polarization involved in immune response|macrophage activation during immune response http://purl.obolibrary.org/obo/GO_0002281 GO:0099190 biolink:BiologicalProcess postsynaptic spectrin-associated cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0099190 goslim_synapse GO:0002282 biolink:BiologicalProcess microglial cell activation involved in immune response The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json microglial cell activation during immune response http://purl.obolibrary.org/obo/GO_0002282 GO:0002298 biolink:BiologicalProcess CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response. go-plus.json CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta T cell development involved in immune response http://purl.obolibrary.org/obo/GO_0002298 GO:0002299 biolink:BiologicalProcess alpha-beta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. go-plus.json alpha-beta intraepithelial T cell development|alpha-beta intraepithelial T lymphocyte differentiation|alpha-beta intraepithelial T-cell differentiation|alpha-beta intraepithelial T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002299 GO:0002294 biolink:BiologicalProcess CD4-positive, alpha-beta T cell differentiation involved in immune response The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. go-plus.json CD4-positive, alpha-beta T cell differentiation during immune response|CD4-positive, alpha-beta T lymphocyte differentiation during immune response|CD4-positive, alpha-beta T cell development involved in immune response|CD4-positive, alpha-beta T-lymphocyte differentiation during immune response|CD4-positive, alpha-beta T-cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0002294 GO:0002295 biolink:BiologicalProcess T-helper cell lineage commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes. go-plus.json Thp lineage commitment|Th0 lineage commitment|T-helper cell fate commitment http://purl.obolibrary.org/obo/GO_0002295 GO:0002296 biolink:BiologicalProcess T-helper 1 cell lineage commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis. go-plus.json Th1 fate commitment|Th1 cell lineage commitment|T-helper 1 cell fate commitment http://purl.obolibrary.org/obo/GO_0002296 GO:0002297 biolink:BiologicalProcess T-helper 2 cell lineage commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy. go-plus.json Th2 fate commitment|T-helper 2 cell fate commitment http://purl.obolibrary.org/obo/GO_0002297 GO:0002290 biolink:BiologicalProcess gamma-delta T cell activation involved in immune response The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. go-plus.json gamma-delta T-cell activation during immune response|gamma-delta T-lymphocyte activation during immune response|gamma-delta T cell activation during immune response|gamma-delta T lymphocyte activation during immune response http://purl.obolibrary.org/obo/GO_0002290 GO:0002291 biolink:BiologicalProcess T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response. go-plus.json T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell http://purl.obolibrary.org/obo/GO_0002291 GO:0002292 biolink:BiologicalProcess T cell differentiation involved in immune response The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. go-plus.json T-cell differentiation during immune response|T cell development involved in immune response|T lymphocyte differentiation during immune response|T cell differentiation during immune response|T-lymphocyte differentiation during immune response http://purl.obolibrary.org/obo/GO_0002292 GO:0002293 biolink:BiologicalProcess alpha-beta T cell differentiation involved in immune response The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. go-plus.json alpha-beta T-cell differentiation during immune response|alpha-beta T cell development involved in immune response|alpha-beta T cell differentiation during immune response|alpha-beta T lymphocyte differentiation during immune response|alpha-beta T-lymphocyte differentiation during immune response http://purl.obolibrary.org/obo/GO_0002293 GO:0002269 biolink:BiologicalProcess leukocyte activation involved in inflammatory response A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. go-plus.json leukocyte activation during inflammatory response|immune cell activation during inflammatory response http://purl.obolibrary.org/obo/GO_0002269 GO:0002265 biolink:BiologicalProcess astrocyte activation involved in immune response A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json astrocyte activation during immune response http://purl.obolibrary.org/obo/GO_0002265 GO:0002266 biolink:BiologicalProcess follicular dendritic cell activation A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0002266 GO:0002267 biolink:BiologicalProcess follicular dendritic cell activation involved in immune response A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json follicular dendritic cell activation during immune response http://purl.obolibrary.org/obo/GO_0002267 GO:0002268 biolink:BiologicalProcess follicular dendritic cell differentiation The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002268 GO:0002261 biolink:BiologicalProcess mucosal lymphocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002261 GO:0002262 biolink:BiologicalProcess myeloid cell homeostasis The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002262 GO:0002263 biolink:BiologicalProcess cell activation involved in immune response A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json cell activation during immune response http://purl.obolibrary.org/obo/GO_0002263 GO:0002264 biolink:BiologicalProcess endothelial cell activation involved in immune response A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json endothelial cell activation during immune response http://purl.obolibrary.org/obo/GO_0002264 GO:0002260 biolink:BiologicalProcess lymphocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002260 CHEBI:90517 biolink:ChemicalSubstance methyl L-leucinato group go-plus.json http://purl.obolibrary.org/obo/CHEBI_90517 chebi_ph7_3 CHEBI:90513 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-Cer(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90513 chebi_ph7_3 CHEBI:90514 biolink:ChemicalSubstance 1-(beta-D-galactosyl)-monododecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90514 chebi_ph7_3 CHEBI:90515 biolink:ChemicalSubstance 3-(beta-D-galactosyl)-monododecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90515 chebi_ph7_3 CHEBI:90516 biolink:ChemicalSubstance L-leucinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90516 chebi_ph7_3 CHEBI:90510 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90510 chebi_ph7_3 CHEBI:90511 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteine methyl ester residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90511 chebi_ph7_3 CHEBI:90512 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-Cer(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90512 chebi_ph7_3 GO:0002276 biolink:BiologicalProcess basophil activation involved in immune response A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. go-plus.json basophil activation during immune response http://purl.obolibrary.org/obo/GO_0002276 GO:0002277 biolink:BiologicalProcess myeloid dendritic cell activation involved in immune response The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json myeloid dendritic cell activation during immune response http://purl.obolibrary.org/obo/GO_0002277 GO:0002278 biolink:BiologicalProcess eosinophil activation involved in immune response The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json eosinophil activation during immune response http://purl.obolibrary.org/obo/GO_0002278 GO:0002279 biolink:BiologicalProcess mast cell activation involved in immune response The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. go-plus.json mast cell activation during immune response http://purl.obolibrary.org/obo/GO_0002279 GO:0002272 biolink:BiologicalProcess plasmacytoid dendritic cell differentiation involved in immune response The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response. go-plus.json plasmacytoid dendritic cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0002272 GO:0002273 biolink:BiologicalProcess plasmacytoid dendritic cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002273 GO:0002274 biolink:BiologicalProcess myeloid leukocyte activation A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json myeloid leucocyte activation http://purl.obolibrary.org/obo/GO_0002274 GO:0002275 biolink:BiologicalProcess myeloid cell activation involved in immune response A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json myeloid cell activation during immune response http://purl.obolibrary.org/obo/GO_0002275 GO:0002270 biolink:BiologicalProcess plasmacytoid dendritic cell activation A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0002270 GO:0002271 biolink:BiologicalProcess plasmacytoid dendritic cell activation involved in immune response A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json plasmacytoid dendritic cell activation during immune response http://purl.obolibrary.org/obo/GO_0002271 CHEBI:145353 biolink:ChemicalSubstance 3beta-hydroxy-4alpha-formyl-4beta-methylsteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_145353 chebi_ph7_3 CHEBI:90506 biolink:ChemicalSubstance 1,2-di-(9Z,12Z-octadecadienoyl)-3-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90506 chebi_ph7_3 CHEBI:90507 biolink:ChemicalSubstance 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90507 chebi_ph7_3 CHEBI:90501 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90501 chebi_ph7_3 GO:0002247 biolink:BiologicalProcess clearance of damaged tissue involved in inflammatory response wound healing The series of events leading to removal of necrotic debris that contribute to an inflammatory response. go-plus.json clearance of damaged tissue during inflammatory response http://purl.obolibrary.org/obo/GO_0002247 GO:0002248 biolink:BiologicalProcess connective tissue replacement involved in inflammatory response wound healing The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared that contribute to an inflammatory response. go-plus.json fibrosis during inflammatory response|connective tissue replacement during inflammatory response http://purl.obolibrary.org/obo/GO_0002248 GO:0002249 biolink:BiologicalProcess lymphocyte anergy Any process contributing to lymphocyte anergy, a state of functional inactivation. go-plus.json http://purl.obolibrary.org/obo/GO_0002249 GO:0002243 biolink:BiologicalProcess detection of parasitic plant The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0002243 GO:0002244 biolink:BiologicalProcess hematopoietic progenitor cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. go-plus.json haematopoietic progenitor cell differentiation|hemopoietic progenitor cell differentiation|haemopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 GO:0002245 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002245 GO:0002246 biolink:BiologicalProcess wound healing involved in inflammatory response The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. go-plus.json inflammatory response wound healing|healing during inflammatory response http://purl.obolibrary.org/obo/GO_0002246 GO:0002240 biolink:BiologicalProcess response to molecule of oomycetes origin Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin. go-plus.json response to oomycetes associated molecule http://purl.obolibrary.org/obo/GO_0002240 CHEBI:89540 biolink:ChemicalSubstance methyl propenyl ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_89540 chebi_ph7_3 GO:0002241 biolink:BiologicalProcess response to parasitic plant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant. go-plus.json http://purl.obolibrary.org/obo/GO_0002241 GO:0002242 biolink:BiologicalProcess defense response to parasitic plant Reactions triggered in response to the presence of a parasitic plant that act to protect an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0002242 GO:0016888 biolink:MolecularActivity endodeoxyribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. EC:3.1.21.-|Reactome:R-HSA-912368 go-plus.json endodeoxyribonuclease activity, producing 5' phosphomonoesters http://purl.obolibrary.org/obo/GO_0016888 GO:0016889 biolink:MolecularActivity endodeoxyribonuclease activity, producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. EC:3.1.22.- go-plus.json endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters http://purl.obolibrary.org/obo/GO_0016889 GO:0016884 biolink:MolecularActivity carbon-nitrogen ligase activity, with glutamine as amido-N-donor Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen. EC:6.3.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0016884 GO:0016885 biolink:MolecularActivity ligase activity, forming carbon-carbon bonds Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.4.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016885 GO:0016886 biolink:MolecularActivity ligase activity, forming phosphoric ester bonds Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.5.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0016886 GO:0016887 biolink:MolecularActivity ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. RHEA:13065|Reactome:R-HSA-6814678|Reactome:R-HSA-6814683|Reactome:R-HSA-6814670|Reactome:R-HSA-5694425|Reactome:R-HSA-8939203|Reactome:R-HSA-9609860|Reactome:R-HSA-6809015|Reactome:R-HSA-5618093|Reactome:R-HSA-5654989|Reactome:R-HSA-72139|Reactome:R-HSA-917693|Reactome:R-HSA-416985|Reactome:R-HSA-3371422|Reactome:R-HSA-8847638|Reactome:R-HSA-8868658|Reactome:R-HSA-6811422|Reactome:R-HSA-159101|Reactome:R-HSA-9706399|Reactome:R-HSA-9038161|Reactome:R-HSA-9668415 go-plus.json ATP monophosphatase activity|adenosine 5'-triphosphatase activity|adenosine triphosphatase activity|adenosinetriphosphatase activity|ATP hydrolase activity|ATP phosphohydrolase activity|ATPase http://purl.obolibrary.org/obo/GO_0016887 GO:0016880 biolink:MolecularActivity acid-ammonia (or amide) ligase activity Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.3.1.- go-plus.json amide synthase activity http://purl.obolibrary.org/obo/GO_0016880 GO:0016881 biolink:MolecularActivity acid-amino acid ligase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.3.2.- go-plus.json peptide synthase activity http://purl.obolibrary.org/obo/GO_0016881 GO:0016882 biolink:MolecularActivity cyclo-ligase activity Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. EC:6.3.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016882 GO:0016883 biolink:MolecularActivity obsolete other carbon-nitrogen ligase activity OBSOLETE. A grouping term for carbon-nitrogen ligases that cannot be more accurately categorized. go-plus.json other carbon-nitrogen ligase activity http://purl.obolibrary.org/obo/GO_0016883 GO:0002258 biolink:BiologicalProcess positive regulation of kinin cascade Any process that activates or increases the frequency, rate, or extent of the kinin cascade. go-plus.json up-regulation of kinin cascade|upregulation of kinin cascade|up regulation of kinin cascade|activation of kinin cascade|stimulation of kinin cascade http://purl.obolibrary.org/obo/GO_0002258 GO:0002259 biolink:BiologicalProcess endothelial cell activation within high endothelial venule involved in immune response A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. go-plus.json endothelial cell activation within high endothelial venule during immune response http://purl.obolibrary.org/obo/GO_0002259 GO:0002254 biolink:BiologicalProcess kinin cascade A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. go-plus.json http://purl.obolibrary.org/obo/GO_0002254 GO:0002255 biolink:BiologicalProcess tissue kallikrein-kinin cascade A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. go-plus.json glandular kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002255 GO:0002256 biolink:BiologicalProcess regulation of kinin cascade Any process that modulates the frequency, rate, or extent of the kinin cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0002256 GO:0002257 biolink:BiologicalProcess negative regulation of kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade. go-plus.json inhibition of kinin cascade|down regulation of kinin cascade|downregulation of kinin cascade|down-regulation of kinin cascade http://purl.obolibrary.org/obo/GO_0002257 GO:0002250 biolink:BiologicalProcess adaptive immune response An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). Wikipedia:Adaptive_immune_system go-plus.json acquired immune response|immune memory response http://purl.obolibrary.org/obo/GO_0002250 GO:0002251 biolink:BiologicalProcess organ or tissue specific immune response An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. go-plus.json immune response in organ or tissue http://purl.obolibrary.org/obo/GO_0002251 GO:0002252 biolink:BiologicalProcess immune effector process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. go-plus.json http://purl.obolibrary.org/obo/GO_0002252 GO:0002253 biolink:BiologicalProcess activation of immune response Any process that initiates an immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0002253 CHEBI:65585 biolink:ChemicalSubstance carnosic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65585 GO:0016899 biolink:MolecularActivity oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule. EC:1.1.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0016899 GO:0016895 biolink:MolecularActivity exodeoxyribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. EC:3.1.11.- go-plus.json exodeoxyribonuclease activity, producing 5' phosphomonoesters|exonuclease VIII activity http://purl.obolibrary.org/obo/GO_0016895 GO:0016896 biolink:MolecularActivity exoribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. Reactome:R-HSA-429860|EC:3.1.13.- go-plus.json exoribonuclease activity, producing 5' phosphomonoesters http://purl.obolibrary.org/obo/GO_0016896 GO:0016897 biolink:MolecularActivity exoribonuclease activity, producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters. EC:3.1.14.- go-plus.json http://purl.obolibrary.org/obo/GO_0016897 GO:0016898 biolink:MolecularActivity oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule. EC:1.1.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0016898 GO:0016891 biolink:MolecularActivity endoribonuclease activity, producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. EC:3.1.26.- go-plus.json http://purl.obolibrary.org/obo/GO_0016891 GO:0016892 biolink:MolecularActivity endoribonuclease activity, producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. EC:3.1.27.- go-plus.json endoribonuclease activity, producing other than 5'-phosphomonoesters http://purl.obolibrary.org/obo/GO_0016892 GO:0016893 biolink:MolecularActivity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. EC:3.1.30.- go-plus.json 5'-endonuclease activity|endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters http://purl.obolibrary.org/obo/GO_0016893 GO:0016894 biolink:MolecularActivity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters. EC:3.1.31.- go-plus.json 3'-endonuclease activity|endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters http://purl.obolibrary.org/obo/GO_0016894 OIO:SubsetProperty biolink:OntologyClass subset_property go-plus.json http://www.geneontology.org/formats/oboInOwl#SubsetProperty GO:0016890 biolink:MolecularActivity site-specific endodeoxyribonuclease activity, specific for altered base Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks. EC:3.1.25.- go-plus.json http://purl.obolibrary.org/obo/GO_0016890 CHEBI:9937 biolink:ChemicalSubstance vasopressin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9937 CHEBI:16517 biolink:ChemicalSubstance cyclotriphosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16517 CHEBI:16515 biolink:ChemicalSubstance 3-ADP-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16515 CHEBI:9907 biolink:ChemicalSubstance ursodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9907 CHEBI:16516 biolink:ChemicalSubstance 2'-deoxyribonucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16516 CHEBI:16513 biolink:ChemicalSubstance hydroxymalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16513 CHEBI:16514 biolink:ChemicalSubstance 4',5,7-trihydroxy-3'-methoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16514 CHEBI:16511 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16511 CHEBI:16512 biolink:ChemicalSubstance (S)-N-methylcanadine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16512 chebi_ph7_3 CHEBI:16510 biolink:ChemicalSubstance 3-hydroxypropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16510 chebi_ph7_3 CHEBI:497734 biolink:ChemicalSubstance L-thialysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_497734 CHEBI:16508 biolink:ChemicalSubstance cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16508 CHEBI:16509 biolink:ChemicalSubstance 1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16509 chebi_ph7_3 CHEBI:16506 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16506 chebi_ph7_3 CHEBI:16507 biolink:ChemicalSubstance 1D-myo-inositol 1,2,4,5,6-pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16507 CHEBI:16504 biolink:ChemicalSubstance monodehydro-L-ascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16504 CHEBI:16505 biolink:ChemicalSubstance dihydrostreptomycin 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16505 CHEBI:16503 biolink:ChemicalSubstance selane go-plus.json http://purl.obolibrary.org/obo/CHEBI_16503 CHEBI:16500 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16500 CHEBI:16501 biolink:ChemicalSubstance L-arabinonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16501 chebi_ph7_3 NCBITaxon:4618 biolink:OrganismalEntity Zingiberales go-plus.json Zingiberiflorae|Scitamineae http://purl.obolibrary.org/obo/NCBITaxon_4618 NCBITaxon:38581 biolink:OrganismalEntity Leishmania major species complex go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_38581 CHEBI:9973 biolink:ChemicalSubstance vibriobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_9973 chebi_ph7_3 NCBITaxon:38568 biolink:OrganismalEntity Leishmania go-plus.json Leishmania http://purl.obolibrary.org/obo/NCBITaxon_38568 NCBITaxon:314294 biolink:OrganismalEntity Cercopithecoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_314294 NCBITaxon:314295 biolink:OrganismalEntity Hominoidea go-plus.json apes|ape http://purl.obolibrary.org/obo/NCBITaxon_314295 UBERON:0008193 biolink:AnatomicalEntity pneumatized bone A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]. go-plus.json pneumatic bone|hollow bone|os pneumaticum http://purl.obolibrary.org/obo/UBERON_0008193 NCBITaxon:314293 biolink:OrganismalEntity Simiiformes go-plus.json Anthropoidea http://purl.obolibrary.org/obo/NCBITaxon_314293 UBERON:0008196 biolink:AnatomicalEntity muscle of pectoral girdle Any muscle organ that is part of a pectoral girdle region. go-plus.json pectoral girdle muscle|muscle of shoulder girdle http://purl.obolibrary.org/obo/UBERON_0008196 GO:0075324 biolink:BiologicalProcess negative regulation of oomycete sporangium development Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated. go-plus.json http://purl.obolibrary.org/obo/GO_0075324 GO:0051357 biolink:BiologicalProcess peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. RESID:AA0377 go-plus.json biosynthetic process of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine|biosynthesis of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine http://purl.obolibrary.org/obo/GO_0051357 GO:0075325 biolink:BiologicalProcess spore dispersal Any process in which an organism disseminates its spores. go-plus.json spore dispersal on or near host during symbiotic interaction|active spore dispersal on or near host during symbiotic interaction|passive spore dispersal on or near host|active spore dispersal on or near host|spore dispersal on or near host http://purl.obolibrary.org/obo/GO_0075325 GO:0051358 biolink:BiologicalProcess peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus. RESID:AA0378 go-plus.json biosynthesis of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0051358 GO:0051355 biolink:BiologicalProcess proprioception involved in equilibrioception The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity. go-plus.json perception of orientation with respect to gravity by proprioception|proprioception during equilibrioception|equilibrioception by proprioception http://purl.obolibrary.org/obo/GO_0051355 GO:0075326 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075326 GO:0051356 biolink:BiologicalProcess visual perception involved in equilibrioception The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity. go-plus.json equilibrioception by visual perception|visual perception during equilibrioception|perception of orientation with respect to gravity by visual perception http://purl.obolibrary.org/obo/GO_0051356 GO:0075327 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0075327 GO:0075328 biolink:BiologicalProcess formation of arbuscule for nutrient acquisition The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation by symbiont of arbuscule for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0075328 GO:0075329 biolink:BiologicalProcess regulation of arbuscule formation for nutrient acquisition from host Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075329 GO:0051359 biolink:BiologicalProcess peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor. RESID:AA0379 go-plus.json biosynthetic process of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0051359 GO:2000742 biolink:BiologicalProcess regulation of anterior head development Any process that modulates the frequency, rate or extent of anterior head development. go-plus.json http://purl.obolibrary.org/obo/GO_2000742 GO:2000743 biolink:BiologicalProcess negative regulation of anterior head development Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development. go-plus.json http://purl.obolibrary.org/obo/GO_2000743 GO:2000744 biolink:BiologicalProcess positive regulation of anterior head development Any process that activates or increases the frequency, rate or extent of anterior head development. go-plus.json http://purl.obolibrary.org/obo/GO_2000744 GO:2000745 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation OBSOLETE. Any positive regulation of transcription from RNA polymerase III promoter that is involved in smooth muscle cell differentiation. go-plus.json activation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from Pol III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol III promoter of smooth muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|activation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000745 GO:2000746 biolink:BiologicalProcess regulation of defecation rhythm Any process that modulates the frequency, rate or extent of defecation rhythm. go-plus.json regulation of defecation motor program|regulation of DMP|regulation of defecation cycle|regulation of defecation behavior http://purl.obolibrary.org/obo/GO_2000746 GO:1905770 biolink:BiologicalProcess regulation of mesodermal cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. go-plus.json regulation of mesoderm cell differentiation http://purl.obolibrary.org/obo/GO_1905770 GO:1905771 biolink:BiologicalProcess negative regulation of mesodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. go-plus.json down-regulation of mesoderm cell differentiation|negative regulation of mesoderm cell differentiation|downregulation of mesodermal cell differentiation|inhibition of mesoderm cell differentiation|down-regulation of mesodermal cell differentiation|inhibition of mesodermal cell differentiation|down regulation of mesoderm cell differentiation|downregulation of mesoderm cell differentiation|down regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_1905771 GO:2000747 biolink:BiologicalProcess negative regulation of defecation rhythm Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm. go-plus.json negative regulation of defecation behavior|negative regulation of defecation cycle|negative regulation of defecation motor program|negative regulation of DMP http://purl.obolibrary.org/obo/GO_2000747 GO:1905772 biolink:BiologicalProcess positive regulation of mesodermal cell differentiation Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. go-plus.json up regulation of mesodermal cell differentiation|activation of mesodermal cell differentiation|up-regulation of mesoderm cell differentiation|upregulation of mesoderm cell differentiation|up-regulation of mesodermal cell differentiation|up regulation of mesoderm cell differentiation|activation of mesoderm cell differentiation|upregulation of mesodermal cell differentiation|positive regulation of mesoderm cell differentiation http://purl.obolibrary.org/obo/GO_1905772 GO:2000748 biolink:BiologicalProcess positive regulation of defecation rhythm Any process that activates or increases the frequency, rate or extent of defecation rhythm. go-plus.json positive regulation of defecation behavior|positive regulation of defecation cycle|positive regulation of DMP|positive regulation of defecation motor program http://purl.obolibrary.org/obo/GO_2000748 GO:2000749 biolink:BiologicalProcess positive regulation of rDNA heterochromatin assembly Any process that activates or increases the frequency, rate or extent of assembly of rDNA heterochromatin. go-plus.json positive regulation of heterochromatic silencing at rDNA|positive regulation of ribosomal DNA heterochromatin assembly|positive regulation of rDNA chromatin silencing|positive regulation of chromatin silencing at ribosomal DNA|positive regulation of chromatin silencing at rDNA http://purl.obolibrary.org/obo/GO_2000749 GO:1905773 biolink:MolecularActivity 8-hydroxy-2'-deoxyguanosine DNA binding Binding to 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA. go-plus.json http://purl.obolibrary.org/obo/GO_1905773 GO:1905763 biolink:MolecularActivity MTREC complex binding Binding to a MTREC complex. go-plus.json NURS complex binding|Mtl1-Red1 core complex binding|PAXT complex binding http://purl.obolibrary.org/obo/GO_1905763 GO:1905764 biolink:BiologicalProcess regulation of protection from non-homologous end joining at telomere Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere. go-plus.json regulation of protection from NHEJ-mediated telomere fusion http://purl.obolibrary.org/obo/GO_1905764 GO:1905765 biolink:BiologicalProcess negative regulation of protection from non-homologous end joining at telomere Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere. go-plus.json inhibition of protection from NHEJ-mediated telomere fusion|down regulation of protection from NHEJ-mediated telomere fusion|downregulation of protection from NHEJ-mediated telomere fusion|down-regulation of protection from non-homologous end joining at telomere|negative regulation of protection from NHEJ-mediated telomere fusion|down-regulation of protection from NHEJ-mediated telomere fusion|downregulation of protection from non-homologous end joining at telomere|down regulation of protection from non-homologous end joining at telomere|inhibition of protection from non-homologous end joining at telomere http://purl.obolibrary.org/obo/GO_1905765 GO:1905766 biolink:BiologicalProcess positive regulation of protection from non-homologous end joining at telomere Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere. go-plus.json upregulation of protection from non-homologous end joining at telomere|up-regulation of protection from NHEJ-mediated telomere fusion|upregulation of protection from NHEJ-mediated telomere fusion|activation of protection from non-homologous end joining at telomere|up-regulation of protection from non-homologous end joining at telomere|up regulation of protection from NHEJ-mediated telomere fusion|activation of protection from NHEJ-mediated telomere fusion|positive regulation of protection from NHEJ-mediated telomere fusion|up regulation of protection from non-homologous end joining at telomere http://purl.obolibrary.org/obo/GO_1905766 GO:1905767 biolink:BiologicalProcess regulation of double-stranded telomeric DNA binding Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_1905767 CHEBI:16579 biolink:ChemicalSubstance anisole go-plus.json http://purl.obolibrary.org/obo/CHEBI_16579 chebi_ph7_3 GO:1905768 biolink:BiologicalProcess negative regulation of double-stranded telomeric DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding. go-plus.json down regulation of double-stranded telomeric DNA binding|downregulation of double-stranded telomeric DNA binding|down-regulation of double-stranded telomeric DNA binding|inhibition of double-stranded telomeric DNA binding http://purl.obolibrary.org/obo/GO_1905768 GO:1905769 biolink:BiologicalProcess positive regulation of double-stranded telomeric DNA binding Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding. go-plus.json upregulation of double-stranded telomeric DNA binding|up regulation of double-stranded telomeric DNA binding|activation of double-stranded telomeric DNA binding|up-regulation of double-stranded telomeric DNA binding http://purl.obolibrary.org/obo/GO_1905769 GO:2000740 biolink:BiologicalProcess negative regulation of mesenchymal stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000740 CHEBI:16577 biolink:ChemicalSubstance 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16577 GO:2000741 biolink:BiologicalProcess positive regulation of mesenchymal stem cell differentiation Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000741 CHEBI:16578 biolink:ChemicalSubstance 4-CDP-2-C-methyl-D-erythritol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16578 IAO:0000116 biolink:OntologyClass editor note go-plus.json http://purl.obolibrary.org/obo/IAO_0000116 GO:0051350 biolink:BiologicalProcess negative regulation of lyase activity Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. go-plus.json lyase inhibitor|down-regulation of lyase activity|downregulation of lyase activity|down regulation of lyase activity|inhibition of lyase activity http://purl.obolibrary.org/obo/GO_0051350 CHEBI:16576 biolink:ChemicalSubstance D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16576 CHEBI:16573 biolink:ChemicalSubstance carbonyl sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16573 chebi_ph7_3 IAO:0000115 biolink:OntologyClass definition go-plus.json http://purl.obolibrary.org/obo/IAO_0000115 GO:0051353 biolink:BiologicalProcess positive regulation of oxidoreductase activity Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. go-plus.json up-regulation of oxidoreductase activity|ribonucleotide reductase activating enzyme activity|upregulation of oxidoreductase activity|oxidoreductase activator|up regulation of oxidoreductase activity|activation of oxidoreductase activity|stimulation of oxidoreductase activity http://purl.obolibrary.org/obo/GO_0051353 GO:0075320 biolink:BiologicalProcess negative regulation of ascus development Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075320 CHEBI:16571 biolink:ChemicalSubstance oxidised poly(vinyl alcohol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16571 chebi_ph7_3 GO:0051354 biolink:BiologicalProcess negative regulation of oxidoreductase activity Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. go-plus.json inhibition of oxidoreductase activity|down regulation of oxidoreductase activity|downregulation of oxidoreductase activity|down-regulation of oxidoreductase activity|oxidoreductase inhibitor http://purl.obolibrary.org/obo/GO_0051354 GO:0075321 biolink:BiologicalProcess oomycete sporangium development The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated. go-plus.json http://purl.obolibrary.org/obo/GO_0075321 CHEBI:16572 biolink:ChemicalSubstance 3-ethylcatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16572 chebi_ph7_3 GO:0051351 biolink:BiologicalProcess positive regulation of ligase activity Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. go-plus.json up regulation of ligase activity|activation of ligase activity|stimulation of ligase activity|up-regulation of ligase activity|ligase activator|upregulation of ligase activity http://purl.obolibrary.org/obo/GO_0051351 GO:0075322 biolink:BiologicalProcess regulation of oomycete sporangium development Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated. go-plus.json http://purl.obolibrary.org/obo/GO_0075322 GO:0075323 biolink:BiologicalProcess positive regulation of oomycete sporangium development Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated. go-plus.json http://purl.obolibrary.org/obo/GO_0075323 GO:0051352 biolink:BiologicalProcess negative regulation of ligase activity Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. go-plus.json down regulation of ligase activity|ligase inhibitor|downregulation of ligase activity|down-regulation of ligase activity|inhibition of ligase activity http://purl.obolibrary.org/obo/GO_0051352 CHEBI:16570 biolink:ChemicalSubstance N(6)-hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16570 GO:0075313 biolink:BiologicalProcess basidium development The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075313 GO:0051368 biolink:BiologicalProcess peptidyl-threonine octanoylation The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin. RESID:AA0386 go-plus.json http://purl.obolibrary.org/obo/GO_0051368 GO:0051369 biolink:BiologicalProcess peptidyl-threonine decanoylation The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin. RESID:AA0387 go-plus.json http://purl.obolibrary.org/obo/GO_0051369 GO:0075314 biolink:BiologicalProcess regulation of basidium development Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075314 GO:0075315 biolink:BiologicalProcess positive regulation of basidium development Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075315 GO:0051366 biolink:BiologicalProcess protein decanoylation The modification of a protein amino acid by formation of an ester or amide with decanoic acid. go-plus.json protein amino acid decanoylation http://purl.obolibrary.org/obo/GO_0051366 GO:0051367 biolink:BiologicalProcess peptidyl-serine decanoylation The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin. RESID:AA0385 go-plus.json http://purl.obolibrary.org/obo/GO_0051367 GO:0075316 biolink:BiologicalProcess negative regulation of basidium development Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0075316 GO:0075317 biolink:BiologicalProcess ascus development The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075317 GO:0075318 biolink:BiologicalProcess regulation of ascus development Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075318 GO:0075319 biolink:BiologicalProcess positive regulation of ascus development Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. go-plus.json http://purl.obolibrary.org/obo/GO_0075319 GO:2000753 biolink:BiologicalProcess positive regulation of glucosylceramide catabolic process Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process. go-plus.json positive regulation of glucosylceramide catabolism|positive regulation of glucosylceramide degradation|positive regulation of glucosylceramide breakdown http://purl.obolibrary.org/obo/GO_2000753 GO:2000754 biolink:BiologicalProcess regulation of sphingomyelin catabolic process Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process. go-plus.json regulation of sphingomyelin degradation|regulation of sphingomyelin breakdown|regulation of sphingomyelin catabolism http://purl.obolibrary.org/obo/GO_2000754 GO:2000755 biolink:BiologicalProcess positive regulation of sphingomyelin catabolic process Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process. go-plus.json positive regulation of sphingomyelin degradation|positive regulation of sphingomyelin catabolism|positive regulation of sphingomyelin breakdown http://purl.obolibrary.org/obo/GO_2000755 GO:2000756 biolink:BiologicalProcess regulation of peptidyl-lysine acetylation Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000756 GO:1905780 biolink:BiologicalProcess regulation of phosphatidylserine exposure on apoptotic cell surface Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface. go-plus.json regulation of externalization of phosphatidylserine http://purl.obolibrary.org/obo/GO_1905780 GO:1905781 biolink:BiologicalProcess negative regulation of phosphatidylserine exposure on apoptotic cell surface Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface. go-plus.json down regulation of externalization of phosphatidylserine|downregulation of externalization of phosphatidylserine|down-regulation of phosphatidylserine exposure on apoptotic cell surface|inhibition of phosphatidylserine exposure on apoptotic cell surface|negative regulation of externalization of phosphatidylserine|down-regulation of externalization of phosphatidylserine|inhibition of externalization of phosphatidylserine|down regulation of phosphatidylserine exposure on apoptotic cell surface|downregulation of phosphatidylserine exposure on apoptotic cell surface http://purl.obolibrary.org/obo/GO_1905781 GO:2000757 biolink:BiologicalProcess negative regulation of peptidyl-lysine acetylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000757 GO:1905782 biolink:BiologicalProcess positive regulation of phosphatidylserine exposure on apoptotic cell surface Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface. go-plus.json upregulation of externalization of phosphatidylserine|up regulation of phosphatidylserine exposure on apoptotic cell surface|activation of phosphatidylserine exposure on apoptotic cell surface|up regulation of externalization of phosphatidylserine|positive regulation of externalization of phosphatidylserine|activation of externalization of phosphatidylserine|up-regulation of phosphatidylserine exposure on apoptotic cell surface|up-regulation of externalization of phosphatidylserine|upregulation of phosphatidylserine exposure on apoptotic cell surface http://purl.obolibrary.org/obo/GO_1905782 GO:2000758 biolink:BiologicalProcess positive regulation of peptidyl-lysine acetylation Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000758 GO:1905783 biolink:BiologicalProcess CENP-A containing nucleosome disassembly The disaggregation of a CENP-A containing nucleosome into its constituent components. go-plus.json centromere specific nucleosome disassembly|centromere-specific nucleosome disassembly|centromeric nucleosome disassembly http://purl.obolibrary.org/obo/GO_1905783 GO:2000759 biolink:BiologicalProcess regulation of N-terminal peptidyl-lysine acetylation Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000759 GO:1905784 biolink:BiologicalProcess regulation of anaphase-promoting complex-dependent catabolic process Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1905784 GO:1905774 biolink:BiologicalProcess regulation of DNA helicase activity Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity. go-plus.json regulation of ATP-dependent DNA helicase activity http://purl.obolibrary.org/obo/GO_1905774 GO:1905775 biolink:BiologicalProcess negative regulation of DNA helicase activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity. go-plus.json negative regulation of ATP-dependent DNA helicase activity|down regulation of ATP-dependent DNA helicase activity|inhibition of DNA helicase activity|downregulation of ATP-dependent DNA helicase activity|down-regulation of ATP-dependent DNA helicase activity|down regulation of DNA helicase activity|downregulation of DNA helicase activity|inhibition of ATP-dependent DNA helicase activity|down-regulation of DNA helicase activity http://purl.obolibrary.org/obo/GO_1905775 IAO:0000120 biolink:OntologyClass metadata complete Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. go-plus.json http://purl.obolibrary.org/obo/IAO_0000120 GO:1905776 biolink:BiologicalProcess positive regulation of DNA helicase activity Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity. go-plus.json upregulation of ATP-dependent DNA helicase activity|up-regulation of DNA helicase activity|up regulation of ATP-dependent DNA helicase activity|activation of ATP-dependent DNA helicase activity|upregulation of DNA helicase activity|up-regulation of ATP-dependent DNA helicase activity|up regulation of DNA helicase activity|activation of DNA helicase activity|positive regulation of ATP-dependent DNA helicase activity http://purl.obolibrary.org/obo/GO_1905776 GO:1905777 biolink:BiologicalProcess regulation of exonuclease activity Any process that modulates the frequency, rate or extent of exonuclease activity. go-plus.json regulation of exonuclease IX activity http://purl.obolibrary.org/obo/GO_1905777 GO:1905778 biolink:BiologicalProcess negative regulation of exonuclease activity Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity. go-plus.json inhibition of exonuclease IX activity|down-regulation of exonuclease activity|down regulation of exonuclease IX activity|downregulation of exonuclease IX activity|downregulation of exonuclease activity|down regulation of exonuclease activity|inhibition of exonuclease activity|negative regulation of exonuclease IX activity|down-regulation of exonuclease IX activity http://purl.obolibrary.org/obo/GO_1905778 CHEBI:16568 biolink:ChemicalSubstance 5,10-methylenetetrahydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16568 GO:2000750 biolink:BiologicalProcess negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000750 GO:1905779 biolink:BiologicalProcess positive regulation of exonuclease activity Any process that activates or increases the frequency, rate or extent of exonuclease activity. go-plus.json up-regulation of exonuclease IX activity|up-regulation of exonuclease activity|activation of exonuclease activity|upregulation of exonuclease IX activity|up regulation of exonuclease activity|up regulation of exonuclease IX activity|positive regulation of exonuclease IX activity|upregulation of exonuclease activity|activation of exonuclease IX activity http://purl.obolibrary.org/obo/GO_1905779 CHEBI:16569 biolink:ChemicalSubstance 3-hydroxyquinolin-4(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16569 chebi_ph7_3 GO:2000751 biolink:BiologicalProcess histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore. go-plus.json histone H3-T3 phosphorylation of CPC localization to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localization to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localisation to kinetochore|histone H3-T3 phosphorylation of CPC complex localization to kinetochore|histone H3-T3 phosphorylation of chromosomal passenger complex localization to kinetochore http://purl.obolibrary.org/obo/GO_2000751 CHEBI:16566 biolink:ChemicalSubstance sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16566 GO:2000752 biolink:BiologicalProcess regulation of glucosylceramide catabolic process Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process. go-plus.json regulation of glucosylceramide breakdown|regulation of glucosylceramide catabolism|regulation of glucosylceramide degradation http://purl.obolibrary.org/obo/GO_2000752 CHEBI:16567 biolink:ChemicalSubstance anthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16567 chebi_ph7_3 GO:0051360 biolink:BiologicalProcess peptide cross-linking via L-asparagine 5-imidazolinone glycine The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. RESID:AA0380 go-plus.json biosynthetic process of protein-protein cross-link via L-asparagine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-asparagine 5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0051360 GO:0051361 biolink:BiologicalProcess peptide cross-linking via L-lysine 5-imidazolinone glycine The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. RESID:AA0381 go-plus.json biosynthetic process of protein-protein cross-link via L-lysine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-lysine 5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0051361 IAO:0000125 biolink:OntologyClass pending final vetting All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor. go-plus.json http://purl.obolibrary.org/obo/IAO_0000125 CHEBI:16562 biolink:ChemicalSubstance 2-phenylacetamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16562 chebi_ph7_3 CHEBI:16563 biolink:ChemicalSubstance tetrahydropalmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16563 chebi_ph7_3 IAO:0000123 biolink:OntologyClass metadata incomplete Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. go-plus.json http://purl.obolibrary.org/obo/IAO_0000123 GO:0051364 biolink:BiologicalProcess N-terminal peptidyl-proline N-formylation The formylation of the N-terminal proline of proteins to form the derivative N-formylproline. RESID:AA0384 go-plus.json http://purl.obolibrary.org/obo/GO_0051364 GO:0051365 biolink:BiologicalProcess cellular response to potassium ion starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions. go-plus.json cellular response to potassium ion deprivation|cellular response to potassium starvation|cellular response to K+ ion starvation|cellular response to K+ ion deprivation http://purl.obolibrary.org/obo/GO_0051365 IAO:0000124 biolink:OntologyClass uncurated Nothing done yet beyond assigning a unique class ID and proposing a preferred term. go-plus.json http://purl.obolibrary.org/obo/IAO_0000124 GO:0075310 biolink:BiologicalProcess regulation of sporangium development Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms. go-plus.json http://purl.obolibrary.org/obo/GO_0075310 GO:0075311 biolink:BiologicalProcess positive regulation of sporangium development Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms. go-plus.json http://purl.obolibrary.org/obo/GO_0075311 GO:0051362 biolink:BiologicalProcess peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species. RESID:AA0382 go-plus.json biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0051362 IAO:0000121 biolink:OntologyClass organizational term term created to ease viewing/sort terms for development purpose, and will not be included in a release go-plus.json http://purl.obolibrary.org/obo/IAO_0000121 IAO:0000122 biolink:OntologyClass ready for release Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." go-plus.json http://purl.obolibrary.org/obo/IAO_0000122 GO:0051363 biolink:BiologicalProcess peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan. RESID:AA0383 go-plus.json http://purl.obolibrary.org/obo/GO_0051363 GO:0075312 biolink:BiologicalProcess negative regulation of sporangium development Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms. go-plus.json http://purl.obolibrary.org/obo/GO_0075312 GO:0051379 biolink:MolecularActivity epinephrine binding Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. go-plus.json adrenaline binding http://purl.obolibrary.org/obo/GO_0051379 GO:0075346 biolink:BiologicalProcess obsolete modification by symbiont of host protein by ubiquitination OBSOLETE. The process in which an organism adds one or more ubiquitin groups to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification by symbiont of host protein by ubiquitylation|modification by symbiont of host protein by ubiquitinylation http://purl.obolibrary.org/obo/GO_0075346 NCBITaxon:4637 biolink:OrganismalEntity Musaceae go-plus.json banana family http://purl.obolibrary.org/obo/NCBITaxon_4637 GO:0051377 biolink:MolecularActivity mannose-ethanolamine phosphotransferase activity Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor. Reactome:R-HSA-162798 go-plus.json phosphoethanolamine transferase activity|ethanolamine phosphate transferase activity|EtN-P transferase activity|addition of ethanolamine phosphate to mannose of GPI precursor http://purl.obolibrary.org/obo/GO_0051377 GO:0051378 biolink:MolecularActivity serotonin binding Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. go-plus.json 5-hydroxytryptamine binding http://purl.obolibrary.org/obo/GO_0051378 GO:2000764 biolink:BiologicalProcess positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis. go-plus.json positive regulation of semaphorin-plexin signalling pathway involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_2000764 GO:2000765 biolink:BiologicalProcess regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translation. go-plus.json http://purl.obolibrary.org/obo/GO_2000765 GO:2000766 biolink:BiologicalProcess negative regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. go-plus.json http://purl.obolibrary.org/obo/GO_2000766 GO:1905790 biolink:BiologicalProcess regulation of mechanosensory behavior Any process that modulates the frequency, rate or extent of mechanosensory behavior. go-plus.json regulation of behavioral response to mechanical stimulus|regulation of mechanosensory behaviour|regulation of behavioural response to mechanical stimulus http://purl.obolibrary.org/obo/GO_1905790 GO:1905791 biolink:BiologicalProcess negative regulation of mechanosensory behavior Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior. go-plus.json downregulation of behavioral response to mechanical stimulus|down-regulation of mechanosensory behaviour|negative regulation of mechanosensory behaviour|inhibition of mechanosensory behavior|down regulation of behavioral response to mechanical stimulus|inhibition of behavioral response to mechanical stimulus|down-regulation of behavioural response to mechanical stimulus|negative regulation of behavioural response to mechanical stimulus|downregulation of mechanosensory behaviour|inhibition of behavioural response to mechanical stimulus|down regulation of mechanosensory behaviour|inhibition of mechanosensory behaviour|down regulation of mechanosensory behavior|downregulation of mechanosensory behavior|negative regulation of behavioral response to mechanical stimulus|down-regulation of behavioral response to mechanical stimulus|down regulation of behavioural response to mechanical stimulus|down-regulation of mechanosensory behavior|downregulation of behavioural response to mechanical stimulus http://purl.obolibrary.org/obo/GO_1905791 GO:2000767 biolink:BiologicalProcess positive regulation of cytoplasmic translation Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. go-plus.json http://purl.obolibrary.org/obo/GO_2000767 GO:1905792 biolink:BiologicalProcess positive regulation of mechanosensory behavior Any process that activates or increases the frequency, rate or extent of mechanosensory behavior. go-plus.json up regulation of behavioural response to mechanical stimulus|activation of behavioural response to mechanical stimulus|up-regulation of mechanosensory behavior|positive regulation of behavioural response to mechanical stimulus|positive regulation of mechanosensory behaviour|upregulation of behavioral response to mechanical stimulus|up regulation of mechanosensory behaviour|upregulation of mechanosensory behavior|up-regulation of behavioural response to mechanical stimulus|up-regulation of behavioral response to mechanical stimulus|activation of behavioral response to mechanical stimulus|upregulation of mechanosensory behaviour|up regulation of mechanosensory behavior|upregulation of behavioural response to mechanical stimulus|activation of mechanosensory behavior|up-regulation of mechanosensory behaviour|positive regulation of behavioral response to mechanical stimulus|activation of mechanosensory behaviour|up regulation of behavioral response to mechanical stimulus http://purl.obolibrary.org/obo/GO_1905792 GO:2000768 biolink:BiologicalProcess positive regulation of nephron tubule epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000768 GO:1905793 biolink:BiologicalProcess protein localization to pericentriolar material A process in which a protein is transported to, or maintained in, a location within a pericentriolar material. go-plus.json protein localisation in pericentriolar material|protein localisation to pericentriolar material|protein localization in pericentriolar material http://purl.obolibrary.org/obo/GO_1905793 GO:2000769 biolink:BiologicalProcess regulation of establishment or maintenance of cell polarity regulating cell shape Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000769 GO:1905794 biolink:BiologicalProcess response to puromycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus. go-plus.json response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine http://purl.obolibrary.org/obo/GO_1905794 GO:1905795 biolink:BiologicalProcess cellular response to puromycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus. go-plus.json cellular response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine http://purl.obolibrary.org/obo/GO_1905795 GO:1905785 biolink:BiologicalProcess negative regulation of anaphase-promoting complex-dependent catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1905785 GO:1905786 biolink:BiologicalProcess positive regulation of anaphase-promoting complex-dependent catabolic process Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1905786 GO:1905787 biolink:BiologicalProcess regulation of detection of mechanical stimulus involved in sensory perception of touch Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. go-plus.json regulation of sensory transduction of mechanical stimulus during perception of touch|regulation of sensory detection of mechanical stimulus during perception of touch|regulation of tactition, sensory detection of mechanical stimulus|regulation of perception of touch, sensory transduction of mechanical stimulus|regulation of perception of touch, sensory detection of mechanical stimulus|regulation of perception of touch, detection of mechanical stimulus http://purl.obolibrary.org/obo/GO_1905787 GO:1905788 biolink:BiologicalProcess negative regulation of detection of mechanical stimulus involved in sensory perception of touch Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. go-plus.json down-regulation of detection of mechanical stimulus involved in sensory perception of touch|negative regulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of perception of touch, sensory detection of mechanical stimulus|downregulation of sensory transduction of mechanical stimulus during perception of touch|negative regulation of perception of touch, detection of mechanical stimulus|down-regulation of perception of touch, detection of mechanical stimulus|down regulation of sensory detection of mechanical stimulus during perception of touch|down regulation of tactition, sensory detection of mechanical stimulus|down regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of detection of mechanical stimulus involved in sensory perception of touch|inhibition of sensory transduction of mechanical stimulus during perception of touch|downregulation of sensory detection of mechanical stimulus during perception of touch|inhibition of perception of touch, sensory detection of mechanical stimulus|inhibition of perception of touch, detection of mechanical stimulus|downregulation of tactition, sensory detection of mechanical stimulus|down regulation of detection of mechanical stimulus involved in sensory perception of touch|down-regulation of perception of touch, sensory transduction of mechanical stimulus|negative regulation of perception of touch, sensory transduction of mechanical stimulus|inhibition of detection of mechanical stimulus involved in sensory perception of touch|negative regulation of sensory detection of mechanical stimulus during perception of touch|down-regulation of sensory detection of mechanical stimulus during perception of touch|downregulation of perception of touch, sensory transduction of mechanical stimulus|down-regulation of tactition, sensory detection of mechanical stimulus|negative regulation of tactition, sensory detection of mechanical stimulus|down regulation of perception of touch, sensory detection of mechanical stimulus|down regulation of perception of touch, detection of mechanical stimulus|inhibition of sensory detection of mechanical stimulus during perception of touch|down regulation of perception of touch, sensory transduction of mechanical stimulus|inhibition of perception of touch, sensory transduction of mechanical stimulus|downregulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of sensory transduction of mechanical stimulus during perception of touch|inhibition of tactition, sensory detection of mechanical stimulus|negative regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of perception of touch, detection of mechanical stimulus http://purl.obolibrary.org/obo/GO_1905788 GO:1905789 biolink:BiologicalProcess positive regulation of detection of mechanical stimulus involved in sensory perception of touch Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. go-plus.json upregulation of perception of touch, sensory transduction of mechanical stimulus|up-regulation of tactition, sensory detection of mechanical stimulus|up regulation of perception of touch, sensory detection of mechanical stimulus|up regulation of perception of touch, detection of mechanical stimulus|activation of perception of touch, sensory detection of mechanical stimulus|positive regulation of sensory transduction of mechanical stimulus during perception of touch|positive regulation of perception of touch, sensory detection of mechanical stimulus|positive regulation of perception of touch, detection of mechanical stimulus|activation of perception of touch, detection of mechanical stimulus|up regulation of sensory transduction of mechanical stimulus during perception of touch|upregulation of sensory detection of mechanical stimulus during perception of touch|up regulation of detection of mechanical stimulus involved in sensory perception of touch|upregulation of tactition, sensory detection of mechanical stimulus|up-regulation of perception of touch, sensory transduction of mechanical stimulus|activation of perception of touch, sensory transduction of mechanical stimulus|up-regulation of perception of touch, sensory detection of mechanical stimulus|upregulation of sensory transduction of mechanical stimulus during perception of touch|up-regulation of perception of touch, detection of mechanical stimulus|up regulation of sensory detection of mechanical stimulus during perception of touch|activation of sensory detection of mechanical stimulus during perception of touch|positive regulation of sensory detection of mechanical stimulus during perception of touch|upregulation of detection of mechanical stimulus involved in sensory perception of touch|up regulation of tactition, sensory detection of mechanical stimulus|positive regulation of perception of touch, sensory transduction of mechanical stimulus|activation of tactition, sensory detection of mechanical stimulus|positive regulation of tactition, sensory detection of mechanical stimulus|up regulation of perception of touch, sensory transduction of mechanical stimulus|upregulation of perception of touch, sensory detection of mechanical stimulus|upregulation of perception of touch, detection of mechanical stimulus|up-regulation of sensory transduction of mechanical stimulus during perception of touch|activation of sensory transduction of mechanical stimulus during perception of touch|up-regulation of detection of mechanical stimulus involved in sensory perception of touch|activation of detection of mechanical stimulus involved in sensory perception of touch|up-regulation of sensory detection of mechanical stimulus during perception of touch http://purl.obolibrary.org/obo/GO_1905789 GO:2000760 biolink:BiologicalProcess negative regulation of N-terminal peptidyl-lysine acetylation Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000760 GO:2000761 biolink:BiologicalProcess positive regulation of N-terminal peptidyl-lysine acetylation Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_2000761 GO:2000762 biolink:BiologicalProcess regulation of phenylpropanoid metabolic process Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process. go-plus.json regulation of phenylpropanoid metabolism http://purl.obolibrary.org/obo/GO_2000762 CHEBI:16599 biolink:ChemicalSubstance 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16599 GO:2000763 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process. go-plus.json positive regulation of transcription from Pol II promoter involved in norepinephrine anabolism|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthesis|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine synthesis|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine formation|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthesis|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthetic process http://purl.obolibrary.org/obo/GO_2000763 GO:0051371 biolink:MolecularActivity muscle alpha-actinin binding Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. go-plus.json alpha-actinin 3 binding|alpha-actinin 2 binding http://purl.obolibrary.org/obo/GO_0051371 CHEBI:16597 biolink:ChemicalSubstance glycerol 1,2-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16597 CHEBI:16598 biolink:ChemicalSubstance DDE go-plus.json http://purl.obolibrary.org/obo/CHEBI_16598 chebi_ph7_3 GO:0051372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051372 NCBITaxon:4640 biolink:OrganismalEntity Musa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4640 GO:0075340 biolink:BiologicalProcess obsolete negative regulation of growth or development of symbiont during interaction with host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. go-plus.json negative regulation of growth or development of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0075340 CHEBI:16595 biolink:ChemicalSubstance 1D-myo-inositol 1,4,5-trisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16595 GO:0075341 biolink:CellularComponent host cell PML body A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism. go-plus.json host cell PML nuclear body|host cell PML NB http://purl.obolibrary.org/obo/GO_0075341 GO:0051370 biolink:MolecularActivity obsolete ZASP binding OBSOLETE. Binding to Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain. go-plus.json ZASP binding|Z-band alternatively spliced PDZ-motif protein binding http://purl.obolibrary.org/obo/GO_0051370 CHEBI:16596 biolink:ChemicalSubstance cyanidin 3-O-rutinoside 5-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_16596 GO:0075342 biolink:BiologicalProcess disruption by symbiont of host cell PML body The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by symbiont of host cell PML body|disassembly by symbiont of host cell PML nuclear body|disassembly by symbiont of host cell PML body during symbiotic interaction|disassembly by symbiont of host cell PML NB|degradation by symbiont of host cell PML body|disassembly by symbiont of host cell PML body http://purl.obolibrary.org/obo/GO_0075342 CHEBI:16593 biolink:ChemicalSubstance L-xylulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16593 GO:0051375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051375 GO:0075343 biolink:BiologicalProcess modulation by symbiont of abscisic acid levels in host The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075343 GO:0051376 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051376 CHEBI:16594 biolink:ChemicalSubstance 2,4-diaminopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16594 GO:0051373 biolink:MolecularActivity FATZ binding Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components. go-plus.json filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle|calsarcin 3 binding|calsarcin 2 binding|calsarcin 1 binding|FATZ 3 binding|FATZ 2 binding|FATZ 1 binding|calsarcin binding http://purl.obolibrary.org/obo/GO_0051373 GO:0075344 biolink:BiologicalProcess obsolete modulation by symbiont of host protein levels OBSOLETE. The alteration by an organism of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075344 CHEBI:16591 biolink:ChemicalSubstance all-trans-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16591 chebi_ph7_3 GO:0075345 biolink:BiologicalProcess obsolete modification by symbiont of host protein OBSOLETE. The covalent alteration by an organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075345 CHEBI:16592 biolink:ChemicalSubstance (S)-canadine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16592 chebi_ph7_3 GO:0051374 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051374 GO:0075335 biolink:BiologicalProcess obsolete positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075335 GO:0075336 biolink:BiologicalProcess obsolete negative regulation of symbiont adenylate cyclase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075336 CHEBI:16590 biolink:ChemicalSubstance O-feruloylgalactaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16590 GO:0051388 biolink:BiologicalProcess positive regulation of neurotrophin TRK receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway. go-plus.json positive regulation of nerve growth factor receptor signalling pathway|positive regulation of NGF receptor signalling pathway|positive regulation of nerve growth factor receptor signaling pathway|upregulation of nerve growth factor receptor signaling pathway|stimulation of nerve growth factor receptor signaling pathway|activation of nerve growth factor receptor signaling pathway|up-regulation of nerve growth factor receptor signaling pathway|positive regulation of NGF receptor signaling pathway|up regulation of nerve growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0051388 GO:0075337 biolink:BiologicalProcess obsolete positive regulation of growth or development of symbiont on or near host surface OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. go-plus.json positive regulation of growth or development of symbiont on or near host surface http://purl.obolibrary.org/obo/GO_0075337 GO:0075338 biolink:BiologicalProcess obsolete modulation of growth or development of symbiont during interaction with host OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. go-plus.json modulation of growth or development of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0075338 GO:0051389 biolink:BiologicalProcess obsolete inactivation of MAPKK activity OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK). go-plus.json termination of MAPKK activity|termination of MAP kinase kinase activity|inactivation of MAP kinase kinase activity http://purl.obolibrary.org/obo/GO_0051389 GO:0075339 biolink:BiologicalProcess obsolete positive regulation of growth or development of symbiont during interaction with host OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. go-plus.json positive regulation of growth or development of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0075339 NCBITaxon:4641 biolink:OrganismalEntity Musa acuminata go-plus.json Musa AA Group|banana|dwarf banana|Musa acuminata AA Group|sweet banana|dessert bananas|Musa nana http://purl.obolibrary.org/obo/NCBITaxon_4641 GO:2000775 biolink:BiologicalProcess histone H3-S10 phosphorylation involved in chromosome condensation Any histone H3-S10 phosphorylation that is involved in chromosome condensation. go-plus.json histone H3 phosphorylation at S10 of chromosome condensation|histone H3S10 phosphorylation of chromosome condensation|histone H3-S10 phosphorylation of chromosome condensation http://purl.obolibrary.org/obo/GO_2000775 GO:2000776 biolink:BiologicalProcess histone H4 acetylation involved in response to DNA damage stimulus Any histone H4 acetylation that is involved in a response to DNA damage stimulus. go-plus.json histone H4 acetylation of cellular response to DNA damage stimulus|histone H4 acetylation of DNA damage response|histone H4 acetylation of response to genotoxic stress|histone H4 acetylation of response to DNA damage stimulus|histone H4 acetylation of cellular DNA damage response http://purl.obolibrary.org/obo/GO_2000776 GO:2000777 biolink:BiologicalProcess positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia. go-plus.json positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to lowered oxygen tension|positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxic stress http://purl.obolibrary.org/obo/GO_2000777 GO:2000778 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000778 GO:2000779 biolink:BiologicalProcess regulation of double-strand break repair Any process that modulates the frequency, rate or extent of double-strand break repair. go-plus.json http://purl.obolibrary.org/obo/GO_2000779 GO:1905796 biolink:BiologicalProcess regulation of intraciliary anterograde transport Any process that modulates the frequency, rate or extent of intraciliary anterograde transport. go-plus.json regulation of intraflagellar anterograde transport http://purl.obolibrary.org/obo/GO_1905796 GO:1905797 biolink:BiologicalProcess negative regulation of intraciliary anterograde transport Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport. go-plus.json down-regulation of intraflagellar anterograde transport|negative regulation of intraflagellar anterograde transport|down-regulation of intraciliary anterograde transport|downregulation of intraflagellar anterograde transport|down regulation of intraflagellar anterograde transport|downregulation of intraciliary anterograde transport|inhibition of intraflagellar anterograde transport|down regulation of intraciliary anterograde transport|inhibition of intraciliary anterograde transport http://purl.obolibrary.org/obo/GO_1905797 GO:1905798 biolink:BiologicalProcess positive regulation of intraciliary anterograde transport Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport. go-plus.json upregulation of intraciliary anterograde transport|activation of intraflagellar anterograde transport|up-regulation of intraflagellar anterograde transport|activation of intraciliary anterograde transport|up-regulation of intraciliary anterograde transport|positive regulation of intraflagellar anterograde transport|up regulation of intraflagellar anterograde transport|up regulation of intraciliary anterograde transport|upregulation of intraflagellar anterograde transport http://purl.obolibrary.org/obo/GO_1905798 GO:1905799 biolink:BiologicalProcess regulation of intraciliary retrograde transport Any process that modulates the frequency, rate or extent of intraciliary retrograde transport. go-plus.json regulation of intraflagellar retrograde transport http://purl.obolibrary.org/obo/GO_1905799 GO:2000770 biolink:BiologicalProcess negative regulation of establishment or maintenance of cell polarity regulating cell shape Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000770 GO:2000771 biolink:BiologicalProcess positive regulation of establishment or maintenance of cell polarity regulating cell shape Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000771 GO:2000772 biolink:BiologicalProcess regulation of cellular senescence Any process that modulates the frequency, rate or extent of cellular senescence. go-plus.json http://purl.obolibrary.org/obo/GO_2000772 GO:2000773 biolink:BiologicalProcess negative regulation of cellular senescence Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. go-plus.json http://purl.obolibrary.org/obo/GO_2000773 CHEBI:16588 biolink:ChemicalSubstance D-hamamelose 2(1)-(dihydrogen phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16588 GO:2000774 biolink:BiologicalProcess positive regulation of cellular senescence Any process that activates or increases the frequency, rate or extent of cellular senescence. go-plus.json http://purl.obolibrary.org/obo/GO_2000774 GO:0051382 biolink:BiologicalProcess kinetochore assembly The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. go-plus.json centromere/kinetochore complex maturation|kinetochore formation|centromere and kinetochore complex maturation|chromosome-kinetochore attachment http://purl.obolibrary.org/obo/GO_0051382 CHEBI:16586 biolink:ChemicalSubstance 6-aminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16586 CHEBI:16587 biolink:ChemicalSubstance 20-hydroxyecdysone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16587 chebi_ph7_3 GO:0051383 biolink:BiologicalProcess kinetochore organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. go-plus.json kinetochore organization and biogenesis|kinetochore organisation http://purl.obolibrary.org/obo/GO_0051383 GO:0051380 biolink:MolecularActivity norepinephrine binding Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. go-plus.json noradrenaline binding http://purl.obolibrary.org/obo/GO_0051380 CHEBI:16584 biolink:ChemicalSubstance isopentenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16584 GO:0075330 biolink:BiologicalProcess positive regulation of arbuscule formation for nutrient acquisition from host Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075330 GO:0051381 biolink:MolecularActivity histamine binding Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json http://purl.obolibrary.org/obo/GO_0051381 CHEBI:16585 biolink:ChemicalSubstance L-lombricine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16585 GO:0075331 biolink:BiologicalProcess negative regulation of arbuscule formation for nutrient acquisition from host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075331 CHEBI:16582 biolink:ChemicalSubstance oxaluric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16582 GO:0051386 biolink:BiologicalProcess regulation of neurotrophin TRK receptor signaling pathway Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway. go-plus.json regulation of nerve growth factor receptor signaling pathway|regulation of nerve growth factor receptor signalling pathway|regulation of NGF receptor signaling pathway|regulation of NGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0051386 CHEBI:16583 biolink:ChemicalSubstance butane-2,3-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16583 chebi_ph7_3 GO:0051387 biolink:BiologicalProcess negative regulation of neurotrophin TRK receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway. go-plus.json downregulation of nerve growth factor receptor signaling pathway|negative regulation of nerve growth factor receptor signaling pathway|negative regulation of nerve growth factor receptor signalling pathway|down regulation of nerve growth factor receptor signaling pathway|inhibition of nerve growth factor receptor signaling pathway|negative regulation of NGF receptor signalling pathway|negative regulation of NGF receptor signaling pathway|down-regulation of nerve growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0051387 GO:0075332 biolink:BiologicalProcess obsolete modulation by host of symbiont adenylate cyclase-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075332 GO:0051384 biolink:BiologicalProcess response to glucocorticoid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. go-plus.json response to glucocorticoid stimulus http://purl.obolibrary.org/obo/GO_0051384 GO:0075333 biolink:BiologicalProcess obsolete positive regulation by host of symbiont adenylate cyclase-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075333 CHEBI:16581 biolink:ChemicalSubstance pregnenolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16581 chebi_ph7_3 GO:0075334 biolink:BiologicalProcess obsolete modulation of symbiont adenylate cyclase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0075334 GO:0051385 biolink:BiologicalProcess response to mineralocorticoid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. go-plus.json response to mineralocorticoid stimulus http://purl.obolibrary.org/obo/GO_0051385 GO:2000706 biolink:BiologicalProcess negative regulation of dense core granule biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000706 GO:2000707 biolink:BiologicalProcess positive regulation of dense core granule biogenesis Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000707 GO:2000708 biolink:BiologicalProcess myosin filament organization involved in cytokinetic actomyosin contractile ring assembly A myosin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis. go-plus.json myosin filament organization of contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring formation|myosin filament organization of cytokinesis, actomyosin contractile ring formation|myosin filament assembly or disassembly of constriction ring assembly|myosin filament organization of constriction ring assembly|myosin filament organization of cytokinesis, actomyosin contractile ring assembly|myosin filament assembly or disassembly of contractile ring assembly|myosin polymerization or depolymerization of contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin ring formation|myosin filament organization of cytokinesis, actomyosin ring formation|myosin filament assembly or disassembly of cytokinesis, actomyosin ring formation|myosin filament organization of cytokinesis, actomyosin ring biosynthesis|myosin filament assembly or disassembly of cytokinesis, actomyosin ring biosynthesis|myosin polymerization or depolymerization of cytokinesis, actomyosin ring biosynthesis|myosin polymerization or depolymerization of cytokinesis, contractile ring assembly|myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly|myosin filament organization of cytokinesis, contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring formation|myosin polymerization or depolymerization of constriction ring assembly http://purl.obolibrary.org/obo/GO_2000708 GO:0051399 biolink:MolecularActivity obsolete N-terminal arginine aminopeptidase activity OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain. go-plus.json arginine aminopeptidase activity|N-terminal arginine aminopeptidase activity|argininyl aminopeptidase activity http://purl.obolibrary.org/obo/GO_0051399 GO:2000709 biolink:BiologicalProcess regulation of maintenance of meiotic sister chromatid cohesion, centromeric Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region. go-plus.json regulation of maintenance of meiotic sister chromatin cohesion at centromere|regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|regulation of maintenance of centromeric meiotic sister chromatin cohesion http://purl.obolibrary.org/obo/GO_2000709 GO:2000700 biolink:BiologicalProcess positive regulation of cardiac muscle cell myoblast differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation. go-plus.json positive regulation of cardiac myoblast differentiation|positive regulation of myocardial precursor cell differentiation http://purl.obolibrary.org/obo/GO_2000700 GO:2000701 biolink:BiologicalProcess glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct. go-plus.json glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|GDNF receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000701 GO:2000702 biolink:BiologicalProcess regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation. go-plus.json regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|regulation of FGFR signaling pathway of ureteric bud formation|regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|regulation of FGF receptor signalling pathway of ureteric bud formation|regulation of FGF receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000702 GO:2000703 biolink:BiologicalProcess negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation. go-plus.json negative regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|negative regulation of FGF receptor signaling pathway of ureteric bud formation|negative regulation of FGF receptor signalling pathway of ureteric bud formation|negative regulation of FGFR signaling pathway of ureteric bud formation|negative regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000703 GO:2000704 biolink:BiologicalProcess positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation. go-plus.json positive regulation of FGFR signaling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|positive regulation of FGF receptor signalling pathway of ureteric bud formation|positive regulation of FGF receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000704 GO:2000705 biolink:BiologicalProcess regulation of dense core granule biogenesis Any process that modulates the frequency, rate or extent of dense core granule biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000705 CHEBI:16537 biolink:ChemicalSubstance galactarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16537 chebi_ph7_3 CHEBI:16535 biolink:ChemicalSubstance piperazine-2,5-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16535 chebi_ph7_3 GO:0051390 biolink:BiologicalProcess obsolete inactivation of MAPKKK activity OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK). go-plus.json inactivation of MAP kinase kinase kinase activity|termination of MAP kinase kinase kinase activity|termination of MAPKKK activity http://purl.obolibrary.org/obo/GO_0051390 CHEBI:16536 biolink:ChemicalSubstance orcinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16536 chebi_ph7_3 CHEBI:16533 biolink:ChemicalSubstance L-tryptophanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16533 CHEBI:16534 biolink:ChemicalSubstance D-galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16534 GO:0051393 biolink:MolecularActivity alpha-actinin binding Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats. go-plus.json alpha-actinin 4 binding|alpha-actinin 1 binding|nonmuscle alpha-actinin binding http://purl.obolibrary.org/obo/GO_0051393 CHEBI:16531 biolink:ChemicalSubstance Renilla luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16531 chebi_ph7_3 GO:0051394 biolink:BiologicalProcess regulation of nerve growth factor receptor activity Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor. go-plus.json regulation of NGF receptor activity http://purl.obolibrary.org/obo/GO_0051394 CHEBI:16532 biolink:ChemicalSubstance N-benzyloxycarbonylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16532 GO:0051391 biolink:BiologicalProcess tRNA acetylation The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_0051391 CHEBI:16530 biolink:ChemicalSubstance 3-methyl-2-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16530 GO:0051392 biolink:MolecularActivity tRNA N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA. go-plus.json tRNA cytidine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0051392 GO:0051397 biolink:MolecularActivity obsolete N-terminal basic amino acid aminopeptidase activity OBSOLETE. Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain. go-plus.json N-terminal basic amino acid aminopeptidase activity http://purl.obolibrary.org/obo/GO_0051397 GO:0051398 biolink:MolecularActivity obsolete N-terminal lysine aminopeptidase activity OBSOLETE. Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain. go-plus.json N-terminal lysine aminopeptidase activity|lysine aminopeptidase activity|lysyl aminopeptidase activity http://purl.obolibrary.org/obo/GO_0051398 GO:0051395 biolink:BiologicalProcess negative regulation of nerve growth factor receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor. go-plus.json downregulation of nerve growth factor receptor activity|down-regulation of nerve growth factor receptor activity|negative regulation of NGF receptor activity|inhibition of nerve growth factor receptor activity|down regulation of nerve growth factor receptor activity http://purl.obolibrary.org/obo/GO_0051395 GO:0051396 biolink:BiologicalProcess positive regulation of nerve growth factor receptor activity Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor. go-plus.json up regulation of nerve growth factor receptor activity|activation of nerve growth factor receptor activity|stimulation of nerve growth factor receptor activity|positive regulation of NGF receptor activity|up-regulation of nerve growth factor receptor activity|upregulation of nerve growth factor receptor activity http://purl.obolibrary.org/obo/GO_0051396 CHEBI:41509 biolink:ChemicalSubstance cholesteryl linoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_41509 chebi_ph7_3 GO:2000717 biolink:BiologicalProcess positive regulation of maintenance of mitotic sister chromatid cohesion, arms Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms. go-plus.json positive regulation of maintenance of sister chromatin cohesion along arms at mitosis|positive regulation of maintenance of mitotic sister chromatin cohesion along arms http://purl.obolibrary.org/obo/GO_2000717 GO:2000718 biolink:BiologicalProcess regulation of maintenance of mitotic sister chromatid cohesion, centromeric Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region. go-plus.json regulation of maintenance of centromeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at centromere at mitosis|regulation of maintenance of mitotic sister chromatin cohesion at centromere http://purl.obolibrary.org/obo/GO_2000718 GO:2000719 biolink:BiologicalProcess negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region. go-plus.json negative regulation of maintenance of mitotic sister chromatin cohesion at centromere|negative regulation of maintenance of sister chromatin cohesion at centromere at mitosis|negative regulation of maintenance of centromeric mitotic sister chromatin cohesion http://purl.obolibrary.org/obo/GO_2000719 GO:2000710 biolink:BiologicalProcess negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region. go-plus.json negative regulation of maintenance of meiotic sister chromatin cohesion at centromere|negative regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|negative regulation of maintenance of centromeric meiotic sister chromatin cohesion http://purl.obolibrary.org/obo/GO_2000710 GO:2000711 biolink:BiologicalProcess positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region. go-plus.json positive regulation of maintenance of centromeric meiotic sister chromatin cohesion|positive regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|positive regulation of maintenance of meiotic sister chromatin cohesion at centromere http://purl.obolibrary.org/obo/GO_2000711 GO:2000712 biolink:BiologicalProcess regulation of maintenance of meiotic sister chromatid cohesion, arms Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms. go-plus.json regulation of maintenance of sister chromatin cohesion along arms at meiosis I|regulation of maintenance of meiotic sister chromatin cohesion along arms http://purl.obolibrary.org/obo/GO_2000712 GO:2000713 biolink:BiologicalProcess negative regulation of maintenance of meiotic sister chromatid cohesion, arms Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms. go-plus.json negative regulation of maintenance of meiotic sister chromatin cohesion along arms|negative regulation of maintenance of sister chromatin cohesion along arms at meiosis I http://purl.obolibrary.org/obo/GO_2000713 GO:2000714 biolink:BiologicalProcess positive regulation of maintenance of meiotic sister chromatid cohesion, arms Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms. go-plus.json positive regulation of maintenance of sister chromatin cohesion along arms at meiosis I|positive regulation of maintenance of meiotic sister chromatin cohesion along arms http://purl.obolibrary.org/obo/GO_2000714 GO:2000715 biolink:BiologicalProcess regulation of maintenance of mitotic sister chromatid cohesion, arms Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms. go-plus.json regulation of maintenance of mitotic sister chromatin cohesion along arms|regulation of maintenance of sister chromatin cohesion along arms at mitosis http://purl.obolibrary.org/obo/GO_2000715 GO:2000716 biolink:BiologicalProcess negative regulation of maintenance of mitotic sister chromatid cohesion, arms Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms. go-plus.json negative regulation of maintenance of sister chromatin cohesion along arms at mitosis|negative regulation of maintenance of mitotic sister chromatin cohesion along arms http://purl.obolibrary.org/obo/GO_2000716 CHEBI:16526 biolink:ChemicalSubstance carbon dioxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16526 chebi_ph7_3 CHEBI:16524 biolink:ChemicalSubstance testosterone acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16524 chebi_ph7_3 CHEBI:16525 biolink:ChemicalSubstance taurochenodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16525 CHEBI:16522 biolink:ChemicalSubstance trans-zeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16522 chebi_ph7_3 CHEBI:16523 biolink:ChemicalSubstance D-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16523 CHEBI:16520 biolink:ChemicalSubstance R'C(R)SH go-plus.json http://purl.obolibrary.org/obo/CHEBI_16520 chebi_ph7_3 CHEBI:16521 biolink:ChemicalSubstance lanosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16521 chebi_ph7_3 GO:2000728 biolink:BiologicalProcess regulation of mRNA export from nucleus in response to heat stress Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress. go-plus.json regulation of mRNA export from cell nucleus during heat stress|regulation of mRNA export from nucleus during heat stress http://purl.obolibrary.org/obo/GO_2000728 GO:2000729 biolink:BiologicalProcess positive regulation of mesenchymal cell proliferation involved in ureter development Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development. go-plus.json positive regulation of ureteral mesenchymal cell proliferation|positive regulation of ureter mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_2000729 GO:2000720 biolink:BiologicalProcess positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region. go-plus.json positive regulation of maintenance of centromeric mitotic sister chromatin cohesion|positive regulation of maintenance of mitotic sister chromatin cohesion at centromere|positive regulation of maintenance of sister chromatin cohesion at centromere at mitosis http://purl.obolibrary.org/obo/GO_2000720 GO:2000721 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Any positive regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation. go-plus.json positive regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of global transcription from Pol II promoter of smooth muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of smooth muscle cell differentiation|positive regulation of transcription from Pol II promoter of smooth muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol II promoter of nonstriated muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of nonstriated muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of global transcription from Pol II promoter of nonstriated muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000721 GO:2000722 biolink:BiologicalProcess regulation of cardiac vascular smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. go-plus.json regulation of heart vascular smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000722 GO:2000723 biolink:BiologicalProcess negative regulation of cardiac vascular smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. go-plus.json negative regulation of heart vascular smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000723 GO:2000724 biolink:BiologicalProcess positive regulation of cardiac vascular smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. go-plus.json positive regulation of heart vascular smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000724 GO:2000725 biolink:BiologicalProcess regulation of cardiac muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. go-plus.json regulation of cardiomyocyte differentiation|regulation of heart muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 GO:2000726 biolink:BiologicalProcess negative regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. go-plus.json negative regulation of cardiomyocyte differentiation|negative regulation of heart muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000726 GO:2000727 biolink:BiologicalProcess positive regulation of cardiac muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. go-plus.json positive regulation of cardiomyocyte differentiation|positive regulation of heart muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000727 CHEBI:16557 biolink:ChemicalSubstance quercetin 3,3',7-trissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16557 CHEBI:16558 biolink:ChemicalSubstance triacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16558 CHEBI:16555 biolink:ChemicalSubstance ethanethioic S-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16555 CHEBI:16556 biolink:ChemicalSubstance CMP-N-acetyl-beta-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16556 CHEBI:16553 biolink:ChemicalSubstance UDP-4-dehydro-6-deoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16553 CHEBI:16554 biolink:ChemicalSubstance sym-homospermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16554 CHEBI:16551 biolink:ChemicalSubstance alpha,alpha-trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16551 chebi_ph7_3 CHEBI:16552 biolink:ChemicalSubstance N-formyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16552 CHEBI:16550 biolink:ChemicalSubstance xanthommatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16550 GO:2000739 biolink:BiologicalProcess regulation of mesenchymal stem cell differentiation Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000739 PR:000037070 biolink:Protein phosphoprotein A protein that includes at least one phosphorylated residue. go-plus.json Prot/PhosRes+|phosphorylated protein http://purl.obolibrary.org/obo/PR_000037070 GO:2000731 biolink:BiologicalProcess negative regulation of termination of RNA polymerase I transcription Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription. go-plus.json negative regulation of transcription termination from Pol I promoter|negative regulation of RNA polymerase I transcription termination|negative regulation of transcription termination from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_2000731 GO:2000732 biolink:BiologicalProcess positive regulation of termination of RNA polymerase I transcription Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription. go-plus.json positive regulation of transcription termination from Pol I promoter|positive regulation of RNA polymerase I transcription termination|positive regulation of transcription termination from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_2000732 GO:2000733 biolink:BiologicalProcess regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation. go-plus.json regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|regulation of GDNF receptor signaling pathway of ureteric bud formation|regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000733 GO:2000734 biolink:BiologicalProcess negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation. go-plus.json negative regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of GDNF receptor signaling pathway of ureteric bud formation|negative regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|negative regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000734 GO:2000735 biolink:BiologicalProcess positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation. go-plus.json positive regulation of GDNF receptor signaling pathway of ureteric bud formation|positive regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|positive regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000735 GO:2000736 biolink:BiologicalProcess regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000736 GO:2000737 biolink:BiologicalProcess negative regulation of stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000737 GO:2000738 biolink:BiologicalProcess positive regulation of stem cell differentiation Any process that activates or increases the frequency, rate or extent of stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000738 CHEBI:16548 biolink:ChemicalSubstance chlordecone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16548 chebi_ph7_3 CHEBI:16549 biolink:ChemicalSubstance UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16549 CHEBI:16546 biolink:ChemicalSubstance 1-O-sinapoyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16546 chebi_ph7_3 CHEBI:16547 biolink:ChemicalSubstance coniferyl aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16547 chebi_ph7_3 CHEBI:16544 biolink:ChemicalSubstance UDP-N-acetyl-D-galactosamine 4,6-bissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16544 GO:2000730 biolink:BiologicalProcess regulation of termination of RNA polymerase I transcription Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription. go-plus.json regulation of RNA polymerase I transcription termination|regulation of transcription termination from RNA polymerase I promoter|regulation of transcription termination from Pol I promoter http://purl.obolibrary.org/obo/GO_2000730 CHEBI:16545 biolink:ChemicalSubstance 5-valerolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16545 chebi_ph7_3 CHEBI:16542 biolink:ChemicalSubstance L-serine phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16542 CHEBI:16543 biolink:ChemicalSubstance N(2)-acetyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16543 CHEBI:16540 biolink:ChemicalSubstance pyridin-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16540 chebi_ph7_3 IAO:0000103 biolink:OntologyClass failed exploratory term The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job go-plus.json http://purl.obolibrary.org/obo/IAO_0000103 CHEBI:16541 biolink:ChemicalSubstance protein polypeptide chain go-plus.json http://purl.obolibrary.org/obo/CHEBI_16541 UBERON:0008114 biolink:AnatomicalEntity joint of girdle A skeletal joint that is part of a appendage girdle region. go-plus.json girdle joint http://purl.obolibrary.org/obo/UBERON_0008114 UBERON:0008115 biolink:AnatomicalEntity surface of cartilage A anatomical surface that is part of a cartilage element. go-plus.json cartilage surface http://purl.obolibrary.org/obo/UBERON_0008115 GO:0002346 biolink:BiologicalProcess B cell positive selection Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor. go-plus.json B lymphocyte positive selection|B-lymphocyte positive selection|B-cell positive selection http://purl.obolibrary.org/obo/GO_0002346 GO:0002347 biolink:BiologicalProcess response to tumor cell Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002347 GO:0002348 biolink:BiologicalProcess central B cell positive selection Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors. go-plus.json central B-cell positive selection|central B lymphocyte positive selection|central B-lymphocyte positive selection http://purl.obolibrary.org/obo/GO_0002348 GO:0002349 biolink:BiologicalProcess histamine production involved in inflammatory response The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json histamine production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002349 GO:0002342 biolink:BiologicalProcess central B cell deletion The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection. go-plus.json central B lymphocyte deletion|central B-lymphocyte deletion|central B-cell deletion http://purl.obolibrary.org/obo/GO_0002342 GO:0002343 biolink:BiologicalProcess peripheral B cell selection Any B cell selection process that occurs in the periphery. go-plus.json peripheral B-cell selection|peripheral B-lymphocyte selection|peripheral B lymphocyte selection http://purl.obolibrary.org/obo/GO_0002343 GO:0002344 biolink:BiologicalProcess B cell affinity maturation The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen. go-plus.json B-cell affinity maturation|B-lymphocyte affinity maturation|B lymphocyte affinity maturation http://purl.obolibrary.org/obo/GO_0002344 GO:0002345 biolink:BiologicalProcess peripheral B cell receptor editing The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation. go-plus.json peripheral B-lymphocyte receptor editing|peripheral B-cell receptor editing|peripheral B lymphocyte receptor editing http://purl.obolibrary.org/obo/GO_0002345 GO:0002340 biolink:BiologicalProcess central B cell selection Any B cell selection process that occurs in the bone marrow. go-plus.json central B-cell selection|central B-lymphocyte selection|central B lymphocyte selection http://purl.obolibrary.org/obo/GO_0002340 GO:0002341 biolink:BiologicalProcess central B cell anergy Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow. go-plus.json central B lymphocyte anergy|central B-lymphocyte anergy|central B-cell anergy http://purl.obolibrary.org/obo/GO_0002341 GO:0016987 biolink:MolecularActivity sigma factor activity Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins. go-plus.json sigma transcription factor|plastid sigma factor activity|DNA-dependent RNA polymerase promoter selection factor|sigma factor activity|promoter selection factor activity|bacterial sigma factor activity|core DNA-dependent RNA polymerase binding promoter specificity activity http://purl.obolibrary.org/obo/GO_0016987 GO:0016988 biolink:MolecularActivity obsolete transcription initiation factor antagonist activity OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity. go-plus.json transcription initiation factor antagonist activity|transcriptional initiation factor antagonist activity http://purl.obolibrary.org/obo/GO_0016988 GO:0016989 biolink:MolecularActivity sigma factor antagonist activity The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity. go-plus.json anti-sigma factor activity http://purl.obolibrary.org/obo/GO_0016989 GO:0016983 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016983 GO:0016984 biolink:MolecularActivity ribulose-bisphosphate carboxylase activity Catalysis of the reaction: 2 (2R)-3-phosphoglycerate + 2 H+ = CO2 + D-ribulose 1,5-bisphosphate + H2O. RHEA:23124|MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN|EC:4.1.1.39 go-plus.json rubisco activity|ribulose 1,5-diphosphate carboxylase/oxygenase activity|D-ribulose-1,5-bisphosphate carboxylase activity|RuBisCO activity|D-ribulose 1,5-diphosphate carboxylase activity|carboxydismutase activity|RuBP carboxylase activity|diphosphoribulose carboxylase activity|ribulose bisphosphate carboxylase/oxygenase activity|ribulose diphosphate carboxylase activity|ribulose diphosphate carboxylase/oxygenase activity|ribulose 1,5-diphosphate carboxylase activity|ribulose 1,5-bisphosphate carboxylase/oxygenase activity|ribulose 1,5-bisphosphate carboxylase activity http://purl.obolibrary.org/obo/GO_0016984 CHEBI:90437 biolink:ChemicalSubstance phosphatidylserine(18:1/18:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90437 GO:0016985 biolink:MolecularActivity mannan endo-1,4-beta-mannosidase activity Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans. EC:3.2.1.78|MetaCyc:3.2.1.78-RXN go-plus.json beta-1,4-mannan 4-mannanohydrolase activity|endo-beta-mannanase activity|1,4-beta-D-mannan mannanohydrolase activity|beta-mannanase B|beta-mannanase activity|endo-1,4-beta-mannanase activity|endo-beta-1,4-mannase activity|endo-1,4-mannanase activity|beta-D-mannanase activity http://purl.obolibrary.org/obo/GO_0016985 GO:0016986 biolink:MolecularActivity obsolete transcription initiation factor activity OBSOLETE. Plays a role in regulating transcription initiation. go-plus.json transcription initiation factor activity|transcriptional initiation factor activity http://purl.obolibrary.org/obo/GO_0016986 CHEBI:90432 biolink:ChemicalSubstance phosphatidylinositol(18:0/20:4) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90432 GO:0016980 biolink:MolecularActivity creatinase activity Catalysis of the reaction: creatine + H(2)O = sarcosine + urea. MetaCyc:CREATINASE-RXN|KEGG_REACTION:R01566|RHEA:22456|EC:3.5.3.3 go-plus.json creatine amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0016980 CHEBI:90433 biolink:ChemicalSubstance phosphatidylserine(18:0/18:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90433 CHEBI:90434 biolink:ChemicalSubstance phosphatidylserine(18:0/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90434 GO:0016982 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016982 CHEBI:90430 biolink:ChemicalSubstance phosphatidylinositol(16:0/20:4) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90430 IAO:0000078 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/IAO_0000078 CHEBI:90431 biolink:ChemicalSubstance phosphatidylinositol(18:0/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90431 GO:0002357 biolink:BiologicalProcess defense response to tumor cell Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0002357 GO:0002358 biolink:BiologicalProcess B cell homeostatic proliferation The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus. go-plus.json B-cell homeostatic proliferation|B-lymphocyte homeostatic proliferation|B lymphocyte homeostatic proliferation http://purl.obolibrary.org/obo/GO_0002358 GO:0002359 biolink:BiologicalProcess B-1 B cell proliferation The expansion of a B-1 B cell by cell division. Follows B cell activation. go-plus.json B-1 B-cell proliferation|B-1 B-lymphocyte proliferation|B-1 B lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0002359 GO:0002353 biolink:BiologicalProcess plasma kallikrein-kinin cascade A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. go-plus.json http://purl.obolibrary.org/obo/GO_0002353 GO:0002354 biolink:BiologicalProcess central B cell negative selection Any process leading to negative selection of B cells in the bone marrow. go-plus.json central B-lymphocyte negative selection|central B-cell negative selection|central B lymphocyte negative selection http://purl.obolibrary.org/obo/GO_0002354 GO:0002355 biolink:BiologicalProcess detection of tumor cell The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0002355 GO:0002356 biolink:BiologicalProcess peripheral B cell negative selection Any process leading to negative selection of B cells in the periphery. go-plus.json peripheral B-lymphocyte negative selection|peripheral B-cell negative selection|peripheral B lymphocyte negative selection http://purl.obolibrary.org/obo/GO_0002356 GO:0002350 biolink:BiologicalProcess peripheral B cell positive selection Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors. go-plus.json peripheral B-cell positive selection|peripheral B lymphocyte positive selection|peripheral B-lymphocyte positive selection http://purl.obolibrary.org/obo/GO_0002350 GO:0002351 biolink:BiologicalProcess serotonin production involved in inflammatory response The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json serotonin production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002351 GO:0002352 biolink:BiologicalProcess B cell negative selection Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion. go-plus.json B-lymphocyte negative selection|B-cell negative selection|B lymphocyte negative selection http://purl.obolibrary.org/obo/GO_0002352 GO:0016998 biolink:BiologicalProcess cell wall macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall. go-plus.json cellular cell wall macromolecule catabolism|cellular cell wall macromolecule degradation|cell wall degradation|cell wall breakdown|cellular cell wall macromolecule breakdown|cellular cell wall macromolecule catabolic process|cell wall catabolism http://purl.obolibrary.org/obo/GO_0016998 GO:0016999 biolink:BiologicalProcess antibiotic metabolic process The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. go-plus.json antibiotic metabolism http://purl.obolibrary.org/obo/GO_0016999 GO:0016994 biolink:MolecularActivity precorrin-6A reductase activity Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+. MetaCyc:1.3.1.54-RXN|RHEA:23408|EC:1.3.1.54 go-plus.json precorrin-6Y:NADP+ oxidoreductase activity|precorrin-6Y:NADP(+) oxidoreductase activity|precorrin-6X reductase activity|precorrin-6B:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0016994 GO:0016995 biolink:MolecularActivity cholesterol oxidase activity Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2. RHEA:32183|EC:1.1.3.6|MetaCyc:CHOLESTEROL-OXIDASE-RXN|KEGG_REACTION:R01459 go-plus.json 3beta-hydroxysteroid:oxygen oxidoreductase activity|cholesterol- O2 oxidoreductase activity|3beta-hydroxy steroid oxidoreductase activity|cholesterol-O2 oxidoreductase activity|cholesterol-O(2) oxidoreductase activity|cholesterol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0016995 GO:0016996 biolink:MolecularActivity endo-alpha-(2,8)-sialidase activity Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids. EC:3.2.1.129|MetaCyc:3.2.1.129-RXN go-plus.json polysialoside (2->8)-alpha-sialosylhydrolase activity|endo-N-acetylneuraminidase activity|poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity|endoneuraminidase activity|poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity|alpha-2,8-sialosylhydrolase activity|endosialidase activity|endo-N-acylneuraminidase activity http://purl.obolibrary.org/obo/GO_0016996 GO:0016997 biolink:MolecularActivity alpha-sialidase activity Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids. go-plus.json http://purl.obolibrary.org/obo/GO_0016997 GO:0016990 biolink:MolecularActivity arginine deiminase activity Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3. RHEA:19597|MetaCyc:ARGININE-DEIMINASE-RXN|EC:3.5.3.6 go-plus.json L-arginine iminohydrolase activity|L-arginine deiminase activity|arginine dihydrolase activity|citrulline iminase activity http://purl.obolibrary.org/obo/GO_0016990 GO:0016991 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016991 GO:0016992 biolink:MolecularActivity lipoate synthase activity Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl. RHEA:16585|Reactome:R-HSA-6793591|EC:2.8.1.8|MetaCyc:RXN0-949 go-plus.json lipoyl synthase activity|LS|protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity|lipoic acid synthase|protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity|LipA http://purl.obolibrary.org/obo/GO_0016992 GO:0016993 biolink:MolecularActivity precorrin-8X methylmutase activity Catalysis of the reaction: precorrin-8X = hydrogenobyrinate. EC:5.4.99.61|RHEA:22512|MetaCyc:5.4.1.2-RXN go-plus.json precorrin-8X 11,12-methylmutase activity|hydrogenobyrinic acid-binding protein activity|HBA synthase activity|precorrin isomerase activity http://purl.obolibrary.org/obo/GO_0016993 CHEBI:90420 biolink:ChemicalSubstance N(6)-(3-O-phospho-D-ribulosyl)-L-lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90420 chebi_ph7_3 GO:0002324 biolink:BiologicalProcess natural killer cell proliferation involved in immune response The expansion of a natural killer cell population by cell division as part of an immune response. go-plus.json NK cell proliferation during immune response|natural killer cell proliferation during immune response http://purl.obolibrary.org/obo/GO_0002324 GO:0002325 biolink:BiologicalProcess natural killer cell differentiation involved in immune response The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response. go-plus.json natural killer cell development involved in immune response|natural killer cell differentiation during immune response|NK cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0002325 GO:0002326 biolink:BiologicalProcess B cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to become any type of B cell. go-plus.json B lymphocyte lineage commitment|B-lymphocyte lineage commitment|B-cell lineage commitment http://purl.obolibrary.org/obo/GO_0002326 GO:0002327 biolink:BiologicalProcess immature B cell differentiation The process in which a precursor cell type acquires the specialized features of an immature B cell. go-plus.json immature B-cell differentiation|immature B-lymphocyte differentiation|immature B cell development|immature B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002327 GO:0002320 biolink:BiologicalProcess lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages. go-plus.json http://purl.obolibrary.org/obo/GO_0002320 GO:0002321 biolink:BiologicalProcess natural killer cell progenitor differentiation The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor. go-plus.json http://purl.obolibrary.org/obo/GO_0002321 GO:0002322 biolink:BiologicalProcess B cell proliferation involved in immune response The expansion of a B cell population by cell division following B cell activation during an immune response. go-plus.json B-lymphocyte proliferation during immune response|B-cell proliferation during immune response|B cell proliferation during immune response|B lymphocyte proliferation during immune response http://purl.obolibrary.org/obo/GO_0002322 GO:0002323 biolink:BiologicalProcess natural killer cell activation involved in immune response The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json natural killer cell activation during immune response|NK cell activation during immune response http://purl.obolibrary.org/obo/GO_0002323 CHEBI:41487 biolink:ChemicalSubstance oxidized Oplophorus luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_41487 chebi_ph7_3 GO:0016969 biolink:MolecularActivity obsolete hemerythrin OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans. go-plus.json hemerythrin http://purl.obolibrary.org/obo/GO_0016969 CHEBI:41482 biolink:ChemicalSubstance (R)-carnitinyl-CoA betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_41482 GO:0016965 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016965 GO:0016966 biolink:MolecularActivity nitric oxide reductase activity Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide. RHEA:30211|EC:1.7.2.5|KEGG_REACTION:R00294|MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN go-plus.json CYP55|nitrous-oxide:acceptor oxidoreductase (NO-forming)|nitrogen oxide reductase activity|cytochrome bc nitric oxide reductase activity|P450nor|nitric-oxide reductase activity|nitrous-oxide:(acceptor) oxidoreductase (NO-forming)|P450 nitric oxide reductase activity http://purl.obolibrary.org/obo/GO_0016966 GO:0016967 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016967 GO:1905700 biolink:BiologicalProcess negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json inhibition of drug transmembrane export|negative regulation of drug transmembrane export|down regulation of drug transmembrane export|downregulation of drug transmembrane export|down-regulation of drug transmembrane export|negative regulation of xenobiotic transmembrane export http://purl.obolibrary.org/obo/GO_1905700 GO:0016968 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016968 GO:1905701 biolink:BiologicalProcess positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json positive regulation of drug transmembrane export|upregulation of drug transmembrane export|up regulation of drug transmembrane export|positive regulation of xenobiotic transmembrane export|activation of drug transmembrane export|up-regulation of drug transmembrane export http://purl.obolibrary.org/obo/GO_1905701 GO:0016961 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016961 CHEBI:90458 biolink:ChemicalSubstance PA(18:0/22:4) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90458 GO:1905702 biolink:BiologicalProcess regulation of inhibitory synapse assembly Any process that modulates the frequency, rate or extent of inhibitory synapse assembly. go-plus.json regulation of inhibitory synapse formation http://purl.obolibrary.org/obo/GO_1905702 GO:0016962 biolink:MolecularActivity obsolete receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json receptor-associated protein activity http://purl.obolibrary.org/obo/GO_0016962 GO:1905703 biolink:BiologicalProcess negative regulation of inhibitory synapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly. go-plus.json downregulation of inhibitory synapse assembly|inhibition of inhibitory synapse formation|down-regulation of inhibitory synapse assembly|inhibition of inhibitory synapse assembly|negative regulation of inhibitory synapse formation|down-regulation of inhibitory synapse formation|downregulation of inhibitory synapse formation|down regulation of inhibitory synapse assembly|down regulation of inhibitory synapse formation http://purl.obolibrary.org/obo/GO_1905703 GO:0016963 biolink:MolecularActivity obsolete alpha-2 macroglobulin receptor-associated protein activity OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains. go-plus.json alpha-2 macroglobulin receptor-associated protein activity http://purl.obolibrary.org/obo/GO_0016963 GO:1905704 biolink:BiologicalProcess positive regulation of inhibitory synapse assembly Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly. go-plus.json upregulation of inhibitory synapse formation|up regulation of inhibitory synapse assembly|activation of inhibitory synapse assembly|up-regulation of inhibitory synapse formation|activation of inhibitory synapse formation|up-regulation of inhibitory synapse assembly|positive regulation of inhibitory synapse formation|up regulation of inhibitory synapse formation|upregulation of inhibitory synapse assembly http://purl.obolibrary.org/obo/GO_1905704 GO:0016964 biolink:MolecularActivity alpha-2 macroglobulin receptor activity Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0016964 GO:1905705 biolink:BiologicalProcess cellular response to paclitaxel Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905705 CHEBI:90454 biolink:ChemicalSubstance lysophosphatidylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90454 GO:1905706 biolink:BiologicalProcess regulation of mitochondrial ATP synthesis coupled proton transport Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport. go-plus.json http://purl.obolibrary.org/obo/GO_1905706 GO:1905707 biolink:BiologicalProcess negative regulation of mitochondrial ATP synthesis coupled proton transport Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport. go-plus.json http://purl.obolibrary.org/obo/GO_1905707 CHEBI:90456 biolink:ChemicalSubstance lysophosphatidylinositol 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90456 GO:1905708 biolink:BiologicalProcess regulation of cell morphogenesis involved in conjugation with cellular fusion Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion. go-plus.json regulation of shmoo orientation|regulation of shmooing http://purl.obolibrary.org/obo/GO_1905708 CHEBI:90457 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-dioctoanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90457 chebi_ph7_3 GO:0016960 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016960 GO:0002328 biolink:BiologicalProcess pro-B cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed. go-plus.json pro-B cell development|pro-B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002328 GO:1905709 biolink:BiologicalProcess negative regulation of membrane permeability Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905709 GO:0002329 biolink:BiologicalProcess pre-B cell differentiation The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. go-plus.json pre-B cell development|pre-B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002329 CHEBI:90452 biolink:ChemicalSubstance lysophosphatidylethanolamine 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_90452 CHEBI:90453 biolink:ChemicalSubstance 1,2-dioctanoyl-3-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90453 chebi_ph7_3 GO:0051302 biolink:BiologicalProcess regulation of cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0051302 GO:0002335 biolink:BiologicalProcess mature B cell differentiation The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. go-plus.json mature B lymphocyte differentiation|mature B-cell differentiation|mature B-lymphocyte differentiation|mature cell development http://purl.obolibrary.org/obo/GO_0002335 GO:0051303 biolink:BiologicalProcess establishment of chromosome localization The directed movement of a chromosome to a specific location. go-plus.json chromosome positioning|establishment of chromosome localisation http://purl.obolibrary.org/obo/GO_0051303 GO:0002336 biolink:BiologicalProcess B-1 B cell lineage commitment The process in which an immature B cell becomes committed to become a B-1 B cell. go-plus.json B-1 B lymphocyte lineage commitment|B-1 B-lymphocyte lineage commitment|B-1 B-cell lineage commitment http://purl.obolibrary.org/obo/GO_0002336 GO:0051300 biolink:BiologicalProcess spindle pole body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome. go-plus.json SPB organization|SPB maturation|spindle pole body maturation|spindle pole body organisation|spindle pole body organization and biogenesis http://purl.obolibrary.org/obo/GO_0051300 GO:0002337 biolink:BiologicalProcess B-1a B cell differentiation The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors. go-plus.json B-1a B-cell differentiation|B-1a B-lymphocyte differentiation|B-1a B cell development|B-1a B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002337 GO:0051301 biolink:BiologicalProcess cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. Wikipedia:Cell_division go-plus.json http://purl.obolibrary.org/obo/GO_0051301 goslim_pir|goslim_drosophila|goslim_generic|goslim_chembl GO:0002338 biolink:BiologicalProcess B-1b B cell differentiation The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5. go-plus.json B-1b B-cell differentiation|B-1b B-lymphocyte differentiation|B-1b B cell development|B-1b B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002338 GO:0051306 biolink:BiologicalProcess mitotic sister chromatid separation The process in which sister chromatids are physically detached from each other during mitosis. go-plus.json mitotic sister chromatid resolution|mitotic chromosome separation|sister chromatid separation during mitosis|chromosome separation during mitosis http://purl.obolibrary.org/obo/GO_0051306 GO:0002331 biolink:BiologicalProcess pre-B cell allelic exclusion Expression of a single heavy chain allele during pre-B cell differentiation. go-plus.json pre-B lymphocyte allelic exclusion http://purl.obolibrary.org/obo/GO_0002331 GO:0051307 biolink:BiologicalProcess meiotic chromosome separation The process in which chromosomes are physically detached from each other during meiosis. go-plus.json chromosome separation during meiosis|meiotic chromosome resolution http://purl.obolibrary.org/obo/GO_0051307 GO:0002332 biolink:BiologicalProcess transitional stage B cell differentiation The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent. go-plus.json transitional stage B-cell differentiation|transitional stage B-lymphocyte differentiation|transitional stage B cell development|transitional stage B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002332 GO:0051304 biolink:BiologicalProcess chromosome separation The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II). go-plus.json rDNA separation|chromatid release http://purl.obolibrary.org/obo/GO_0051304 GO:0002333 biolink:BiologicalProcess transitional one stage B cell differentiation The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21. go-plus.json transitional one stage B-cell differentiation|transitional one stage B-lymphocyte differentiation|T1 stage B cell differentiation|transitional one stage B cell development|transitional one stage B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002333 GO:0002334 biolink:BiologicalProcess transitional two stage B cell differentiation The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21. go-plus.json transitional two stage B cell development|transitional two stage B lymphocyte differentiation|T2 stage B cell differentiation|transitional two stage B-cell differentiation|transitional two stage B-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002334 GO:0051305 biolink:BiologicalProcess chromosome movement towards spindle pole The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes. go-plus.json chromosome movement|chromosome migration to spindle pole|chromosome movement to spindle pole http://purl.obolibrary.org/obo/GO_0051305 GO:0051308 biolink:BiologicalProcess male meiosis chromosome separation The process in which paired chromosomes are physically detached from each other during male meiosis. go-plus.json male meiosis chromosome resolution|chromosome separation during male meiosis http://purl.obolibrary.org/obo/GO_0051308 GO:0051309 biolink:BiologicalProcess female meiosis chromosome separation The process in which paired chromosomes are physically detached from each other during female meiosis. go-plus.json female meiosis chromosome resolution|chromosome separation during female meiosis http://purl.obolibrary.org/obo/GO_0051309 GO:0002330 biolink:BiologicalProcess pre-B cell receptor expression The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002330 GO:0016976 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016976 GO:0016977 biolink:MolecularActivity chitosanase activity Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan. MetaCyc:3.2.1.132-RXN|EC:3.2.1.132 go-plus.json chitosan N-acetylglucosaminohydrolase activity http://purl.obolibrary.org/obo/GO_0016977 GO:1905710 biolink:BiologicalProcess positive regulation of membrane permeability Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905710 GO:0016978 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016978 GO:0016979 biolink:MolecularActivity lipoate-protein ligase activity Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP. EC:6.3.1.20|RHEA:49288|MetaCyc:RXN-13039|MetaCyc:RXN-8655|MetaCyc:RXN-8654|MetaCyc:RXN0-1141 go-plus.json lipoate-protein ligase activity (lipoylation of glycine cleavage complex)|lipoate-protein ligase A activity|lipoate-protein ligase B activity http://purl.obolibrary.org/obo/GO_0016979 GO:1905711 biolink:BiologicalProcess response to phosphatidylethanolamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus. go-plus.json response to phosphatidyl(amino)ethanols|response to phosphatidylethanolamines|response to PtdEtn|response to PE http://purl.obolibrary.org/obo/GO_1905711 GO:0016972 biolink:MolecularActivity thiol oxidase activity Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O2. EC:1.8.3.2|UM-BBD_reactionID:r1293|RHEA:17357|MetaCyc:THIOL-OXIDASE-RXN go-plus.json thiol:oxygen oxidoreductase activity|sulfhydryl oxidase activity http://purl.obolibrary.org/obo/GO_0016972 GO:1905712 biolink:BiologicalProcess cellular response to phosphatidylethanolamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus. go-plus.json cellular response to phosphatidyl(amino)ethanols|cellular response to phosphatidylethanolamines|cellular response to PE|cellular response to PtdEtn http://purl.obolibrary.org/obo/GO_1905712 GO:0016973 biolink:BiologicalProcess poly(A)+ mRNA export from nucleus The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm. go-plus.json poly(A)+ mRNA transport from nucleus to cytoplasm|polyadenylated mRNA export from nucleus|poly(A) mRNA export from nucleus|poly(A)+ mRNA-nucleus export|poly(A)+ mRNA export out of nucleus|poly(A)+ mRNA export from cell nucleus http://purl.obolibrary.org/obo/GO_0016973 GO:1905713 biolink:BiologicalProcess obsolete mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium ion concentration OBSOLETE. Any mitochondrial calcium uptake that is involved in regulation of presynaptic cytosolic calcium ion concentration. go-plus.json calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium levels|mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_1905713 GO:1905714 biolink:BiologicalProcess obsolete mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium ion concentration OBSOLETE. Any mitochondrial calcium release that is involved in regulation of presynaptic cytosolic calcium ion concentration. go-plus.json mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_1905714 GO:0016974 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016974 GO:1905715 biolink:BiologicalProcess regulation of cornification Any process that modulates the frequency, rate or extent of cornification. go-plus.json http://purl.obolibrary.org/obo/GO_1905715 GO:0016975 biolink:MolecularActivity obsolete alpha-2 macroglobulin OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates. go-plus.json alpha-2 macroglobulin http://purl.obolibrary.org/obo/GO_0016975 GO:1905716 biolink:BiologicalProcess negative regulation of cornification Any process that stops, prevents or reduces the frequency, rate or extent of cornification. go-plus.json down regulation of cornification|downregulation of cornification|down-regulation of cornification|inhibition of cornification http://purl.obolibrary.org/obo/GO_1905716 GO:1905717 biolink:BiologicalProcess positive regulation of cornification Any process that activates or increases the frequency, rate or extent of cornification. go-plus.json upregulation of cornification|up regulation of cornification|activation of cornification|up-regulation of cornification http://purl.obolibrary.org/obo/GO_1905717 GO:1905718 biolink:CellularComponent obsolete mitotic spindle astral microtubule end OBSOLETE. Any microtubule end that is part of a mitotic spindle astral microtubule. go-plus.json mitotic spindle astral microtubule tip http://purl.obolibrary.org/obo/GO_1905718 GO:0016970 biolink:MolecularActivity obsolete hemocyanin OBSOLETE. A blue, copper-containing oxygen carrier present in many molluscs and arthropods. go-plus.json hemocyanin http://purl.obolibrary.org/obo/GO_0016970 GO:1905719 biolink:BiologicalProcess protein localization to perinuclear region of cytoplasm A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm. go-plus.json protein localisation to perinuclear region of cytoplasm|protein localization to perinuclear cytoplasm|protein localization in perinuclear region of cytoplasm|protein localisation in perinuclear region of cytoplasm http://purl.obolibrary.org/obo/GO_1905719 GO:0016971 biolink:MolecularActivity flavin-linked sulfhydryl oxidase activity Catalysis of the formation of disulfide bridges in proteins using FAD as the electron acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0016971 GO:0002339 biolink:BiologicalProcess B cell selection The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. go-plus.json B-cell selection|B-lymphocyte selection|B lymphocyte selection http://purl.obolibrary.org/obo/GO_0002339 GO:0002302 biolink:BiologicalProcess CD8-positive, alpha-beta T cell differentiation involved in immune response The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. go-plus.json CD8-positive, alpha-beta T lymphocyte differentiation during immune response|CD8-positive, alpha-beta T cell differentiation during immune response|CD8-positive, alpha-beta T-lymphocyte differentiation during immune response|CD8-positive, alpha-beta T-cell differentiation during immune response|CD8-positive, alpha-beta intraepithelial T cell development http://purl.obolibrary.org/obo/GO_0002302 GO:0051313 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051313 GO:0002303 biolink:BiologicalProcess gamma-delta T cell differentiation involved in immune response The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. go-plus.json gamma-delta T-lymphocyte differentiation during immune response|gamma-delta T cell differentiation during immune response|gamma-delta T-cell differentiation during immune response|gamma-delta T cell development involved in immune response|gamma-delta T lymphocyte differentiation during immune response http://purl.obolibrary.org/obo/GO_0002303 GO:0051314 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051314 GO:0002304 biolink:BiologicalProcess gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. go-plus.json gamma-delta intraepithelial T-lymphocyte differentiation|gamma-delta intraepithelial T cell development|gamma-delta intraepithelial T lymphocyte differentiation|gamma-delta intraepithelial T-cell differentiation http://purl.obolibrary.org/obo/GO_0002304 GO:0051311 biolink:BiologicalProcess meiotic metaphase plate congression The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis. go-plus.json metaphase plate congression during meiosis http://purl.obolibrary.org/obo/GO_0051311 GO:0002305 biolink:BiologicalProcess CD8-positive, gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. go-plus.json CD8-positive, gamma-delta intraepithelial T cell development|CD8-positive, gamma-delta intraepithelial T lymphocyte differentiation|CD8-positive, gamma-delta intraepithelial T-cell differentiation|CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002305 GO:0051312 biolink:BiologicalProcess chromosome decondensation The alteration of chromosome structure from the condensed form to a relaxed disperse form. go-plus.json http://purl.obolibrary.org/obo/GO_0051312 GO:0051317 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051317 GO:0051318 biolink:BiologicalProcess G1 phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis. Wikipedia:G1_phase go-plus.json http://purl.obolibrary.org/obo/GO_0051318 gocheck_do_not_annotate CHEBI:89484 biolink:ChemicalSubstance 4-heptanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_89484 chebi_ph7_3 GO:0002300 biolink:BiologicalProcess CD8-positive, alpha-beta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. go-plus.json CD8-positive, alpha-beta intraepithelial T-cell differentiation|CD8-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD8-positive, alpha-beta intraepithelial T cell development|CD8-positive, alpha-beta intraepithelial T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002300 GO:0051315 biolink:BiologicalProcess attachment of mitotic spindle microtubules to kinetochore The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression. go-plus.json attachment of spindle microtubules to mitotic chromosome|attachment of spindle microtubules to kinetochore during mitosis|attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|attachment of spindle microtubules to kinetochore involved in mitosis|mitotic bipolar attachment http://purl.obolibrary.org/obo/GO_0051315 GO:0002301 biolink:BiologicalProcess CD4-positive, alpha-beta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. go-plus.json CD4-positive, alpha-beta intraepithelial T lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T-cell differentiation|CD4-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T cell development http://purl.obolibrary.org/obo/GO_0002301 GO:0051316 biolink:BiologicalProcess attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation. go-plus.json attachment of spindle microtubules to meiotic chromosome|attachment of spindle microtubules to kinetochore during meiotic chromosome segregation|attachment of spindle microtubules to kinetochore during meiosis http://purl.obolibrary.org/obo/GO_0051316 GO:2000786 biolink:BiologicalProcess positive regulation of autophagosome assembly Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. go-plus.json positive regulation of autophagic vacuole formation|positive regulation of PAS formation|positive regulation of autophagosome biosynthesis|positive regulation of autophagosome formation|positive regulation of autophagic vacuole assembly http://purl.obolibrary.org/obo/GO_2000786 UBERON:6001730 biolink:AnatomicalEntity insect larval head Any head that is part of some larva. go-plus.json http://purl.obolibrary.org/obo/UBERON_6001730 GO:2000787 biolink:BiologicalProcess regulation of venous endothelial cell fate commitment Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment. go-plus.json http://purl.obolibrary.org/obo/GO_2000787 GO:2000788 biolink:BiologicalProcess negative regulation of venous endothelial cell fate commitment Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment. go-plus.json http://purl.obolibrary.org/obo/GO_2000788 GO:0051319 biolink:BiologicalProcess G2 phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis). Wikipedia:G2_phase go-plus.json http://purl.obolibrary.org/obo/GO_0051319 gocheck_do_not_annotate GO:2000789 biolink:BiologicalProcess positive regulation of venous endothelial cell fate commitment Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment. go-plus.json http://purl.obolibrary.org/obo/GO_2000789 GO:0016947 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016947 GO:0016948 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016948 GO:0016949 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016949 UBERON:6001732 biolink:AnatomicalEntity insect larval head segment Any segment that is part of some larval head. go-plus.json http://purl.obolibrary.org/obo/UBERON_6001732 GO:0016943 biolink:MolecularActivity obsolete RNA polymerase I transcription elongation factor activity OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation. go-plus.json RNA polymerase I transcription elongation factor activity|Pol I transcription elongation factor activity http://purl.obolibrary.org/obo/GO_0016943 GO:0016944 biolink:MolecularActivity obsolete RNA polymerase II transcription elongation factor activity OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation. go-plus.json RNA polymerase II transcription elongation factor activity|Pol II transcription elongation factor activity http://purl.obolibrary.org/obo/GO_0016944 GO:1905720 biolink:CellularComponent cytoplasmic microtubule bundle Any microtubule bundle that is part of a cytoplasm. go-plus.json microtubule fascicle of cytoplasm|microtubule bundle of cytoplasm http://purl.obolibrary.org/obo/GO_1905720 GO:2000780 biolink:BiologicalProcess negative regulation of double-strand break repair Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair. go-plus.json http://purl.obolibrary.org/obo/GO_2000780 GO:0016945 biolink:MolecularActivity obsolete RNA polymerase III transcription elongation factor activity OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation. go-plus.json RNA polymerase III transcription elongation factor activity|Pol III transcription elongation factor activity http://purl.obolibrary.org/obo/GO_0016945 GO:1905721 biolink:CellularComponent mitotic spindle astral microtubule end Any microtubule end that is part of a mitotic spindle astral microtubule. go-plus.json mitotic spindle astral microtubule tip http://purl.obolibrary.org/obo/GO_1905721 GO:2000781 biolink:BiologicalProcess positive regulation of double-strand break repair Any process that activates or increases the frequency, rate or extent of double-strand break repair. go-plus.json http://purl.obolibrary.org/obo/GO_2000781 GO:1905722 biolink:BiologicalProcess regulation of trypanothione biosynthetic process Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process. go-plus.json regulation of trypanothione anabolism|regulation of trypanothione biosynthesis|regulation of trypanothione synthesis|regulation of trypanothione formation http://purl.obolibrary.org/obo/GO_1905722 GO:0016946 biolink:MolecularActivity obsolete cathepsin F activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2. go-plus.json cathepsin F activity http://purl.obolibrary.org/obo/GO_0016946 GO:1905723 biolink:BiologicalProcess negative regulation of trypanothione biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process. go-plus.json negative regulation of trypanothione synthesis|down-regulation of trypanothione synthesis|inhibition of trypanothione anabolism|down-regulation of trypanothione formation|negative regulation of trypanothione formation|inhibition of trypanothione synthesis|down-regulation of trypanothione biosynthetic process|down-regulation of trypanothione biosynthesis|negative regulation of trypanothione biosynthesis|inhibition of trypanothione formation|down regulation of trypanothione anabolism|downregulation of trypanothione biosynthesis|downregulation of trypanothione biosynthetic process|down regulation of trypanothione synthesis|downregulation of trypanothione anabolism|down regulation of trypanothione biosynthetic process|down regulation of trypanothione biosynthesis|inhibition of trypanothione biosynthesis|inhibition of trypanothione biosynthetic process|down regulation of trypanothione formation|downregulation of trypanothione synthesis|downregulation of trypanothione formation|negative regulation of trypanothione anabolism|down-regulation of trypanothione anabolism http://purl.obolibrary.org/obo/GO_1905723 GO:2000782 biolink:BiologicalProcess regulation of establishment of cell polarity regulating cell shape Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000782 GO:1905724 biolink:BiologicalProcess positive regulation of trypanothione biosynthetic process Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process. go-plus.json positive regulation of trypanothione formation|activation of trypanothione formation|up-regulation of trypanothione biosynthetic process|up-regulation of trypanothione biosynthesis|activation of trypanothione biosynthesis|activation of trypanothione biosynthetic process|up-regulation of trypanothione anabolism|up-regulation of trypanothione synthesis|up-regulation of trypanothione formation|positive regulation of trypanothione biosynthesis|upregulation of trypanothione anabolism|up regulation of trypanothione biosynthetic process|up regulation of trypanothione biosynthesis|upregulation of trypanothione synthesis|upregulation of trypanothione formation|up regulation of trypanothione anabolism|upregulation of trypanothione biosynthesis|positive regulation of trypanothione anabolism|upregulation of trypanothione biosynthetic process|activation of trypanothione anabolism|up regulation of trypanothione synthesis|positive regulation of trypanothione synthesis|activation of trypanothione synthesis|up regulation of trypanothione formation http://purl.obolibrary.org/obo/GO_1905724 GO:2000783 biolink:BiologicalProcess negative regulation of establishment of cell polarity regulating cell shape Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000783 GO:0016940 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016940 GO:0016941 biolink:MolecularActivity natriuretic peptide receptor activity Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016941 GO:1905725 biolink:BiologicalProcess protein localization to microtubule end A process in which a protein is transported to, or maintained in, a location at a microtubule end. go-plus.json protein localisation to microtubule end http://purl.obolibrary.org/obo/GO_1905725 GO:2000784 biolink:BiologicalProcess positive regulation of establishment of cell polarity regulating cell shape Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape. go-plus.json http://purl.obolibrary.org/obo/GO_2000784 GO:2000785 biolink:BiologicalProcess regulation of autophagosome assembly Any process that modulates the frequency, rate or extent of autophagosome assembly. go-plus.json regulation of PAS formation|regulation of autophagosome formation|regulation of autophagic vacuole formation|regulation of autophagosome biosynthesis|regulation of autophagic vacuole assembly http://purl.obolibrary.org/obo/GO_2000785 GO:0016942 biolink:CellularComponent insulin-like growth factor binding protein complex A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development. go-plus.json IGF binding protein complex http://purl.obolibrary.org/obo/GO_0016942 goslim_pir CHEBI:16498 biolink:ChemicalSubstance N-acylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16498 CHEBI:90477 biolink:ChemicalSubstance 3-(beta-D-galactosyl)-1,2-bis(long-chain acyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90477 chebi_ph7_3 CHEBI:16496 biolink:ChemicalSubstance 5beta-cholestane-3alpha,7alpha,12alpha-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16496 chebi_ph7_3 CHEBI:16497 biolink:ChemicalSubstance dGTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_16497 GO:0002306 biolink:BiologicalProcess CD4-positive gamma-delta intraepithelial T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. go-plus.json CD4-positive, gamma-delta intraepithelial T cell development|CD4-positive, gamma-delta intraepithelial T lymphocyte differentiation|CD4-positive, gamma-delta intraepithelial T-cell differentiation|CD4-positive, gamma-delta intraepithelial T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002306 CHEBI:16494 biolink:ChemicalSubstance lipoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16494 CHEBI:16495 biolink:ChemicalSubstance 4alpha-methyllathosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16495 chebi_ph7_3 GO:0002307 biolink:BiologicalProcess CD8-positive, alpha-beta regulatory T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell. go-plus.json CD8-positive, alpha-beta regulatory T-cell differentiation|CD8-positive, alpha-beta regulatory T-lymphocyte differentiation|CD8-positive, alpha-beta regulatory T cell development|CD8-positive, alpha-beta regulatory T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002307 GO:0051310 biolink:BiologicalProcess metaphase plate congression The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle. go-plus.json chromosome congression http://purl.obolibrary.org/obo/GO_0051310 CHEBI:16492 biolink:ChemicalSubstance nucleoside 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16492 GO:0002308 biolink:BiologicalProcess CD8-positive, alpha-beta cytotoxic T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell. go-plus.json CD8-positive, alpha-beta cytotoxic T-lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T cell development|CD8-positive, alpha-beta cytotoxic T lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T-cell differentiation http://purl.obolibrary.org/obo/GO_0002308 GO:0002309 biolink:BiologicalProcess T cell proliferation involved in immune response The expansion of a T cell population by cell division as part of an immune response. go-plus.json T-cell proliferation during immune response|T cell proliferation during immune response|T lymphocyte proliferation during immune response|T-lymphocyte proliferation during immune response http://purl.obolibrary.org/obo/GO_0002309 CHEBI:90475 biolink:ChemicalSubstance 3-(beta-D-galactosyl)-2-mono(long-chain acyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90475 chebi_ph7_3 CHEBI:16493 biolink:ChemicalSubstance 1-deoxy-D-xylulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16493 CHEBI:16490 biolink:ChemicalSubstance S-adenosyl-4-methylthio-2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16490 chebi_ph7_3 GO:0051324 biolink:BiologicalProcess prophase The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. Wikipedia:Prophase go-plus.json http://purl.obolibrary.org/obo/GO_0051324 gocheck_do_not_annotate GO:0002313 biolink:BiologicalProcess mature B cell differentiation involved in immune response The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response. go-plus.json mature B cell development involved in immune response|mature B-lymphocyte differentiation during immune response|mature B-cell differentiation during immune response|mature B cell differentiation during immune response|mature B lymphocyte differentiation during immune response http://purl.obolibrary.org/obo/GO_0002313 GO:0051325 biolink:BiologicalProcess interphase The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs. Wikipedia:Interphase go-plus.json karyostasis|resting phase http://purl.obolibrary.org/obo/GO_0051325 gocheck_do_not_annotate GO:0002314 biolink:BiologicalProcess germinal center B cell differentiation The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). go-plus.json germinal center B cell development|germinal center B lymphocyte differentiation|germinal center B-cell differentiation|germinal center B-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002314 GO:0002315 biolink:BiologicalProcess marginal zone B cell differentiation The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). go-plus.json marginal zone B-cell differentiation|marginal zone B-lymphocyte differentiation|marginal zone B cell development|marginal zone B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002315 GO:0051322 biolink:BiologicalProcess anaphase The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle. Wikipedia:Anaphase go-plus.json http://purl.obolibrary.org/obo/GO_0051322 gocheck_do_not_annotate GO:0051323 biolink:BiologicalProcess metaphase The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell. Wikipedia:Metaphase go-plus.json http://purl.obolibrary.org/obo/GO_0051323 gocheck_do_not_annotate GO:0002316 biolink:BiologicalProcess follicular B cell differentiation The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region. go-plus.json follicular B cell development|follicular B lymphocyte differentiation|follicular B-cell differentiation|follicular B-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0002316 GO:0051328 biolink:BiologicalProcess meiotic interphase The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA. go-plus.json interphase of meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051328 gocheck_do_not_annotate GO:0051329 biolink:BiologicalProcess mitotic interphase The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs. go-plus.json interphase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0051329 gocheck_do_not_annotate GO:0002310 biolink:BiologicalProcess alpha-beta T cell proliferation involved in immune response The expansion of an alpha-beta T cell population by cell division as part of an immune response. go-plus.json alpha-beta T-lymphocyte proliferation during immune response|alpha-beta T-cell proliferation during immune response|alpha-beta T cell proliferation during immune response|alpha-beta T lymphocyte proliferation during immune response http://purl.obolibrary.org/obo/GO_0002310 GO:0051326 biolink:BiologicalProcess telophase The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. Wikipedia:Telophase go-plus.json http://purl.obolibrary.org/obo/GO_0051326 gocheck_do_not_annotate GO:0002311 biolink:BiologicalProcess gamma-delta T cell proliferation involved in immune response The expansion of a gamma-delta T cell population by cell division as part of an immune response. go-plus.json gamma-delta T cell proliferation during immune response|gamma-delta T lymphocyte proliferation during immune response|gamma-delta T-lymphocyte proliferation during immune response|gamma-delta T-cell proliferation during immune response http://purl.obolibrary.org/obo/GO_0002311 GO:0002312 biolink:BiologicalProcess B cell activation involved in immune response The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json B lymphocyte activation during immune response|B-cell activation during immune response|B-lymphocyte activation during immune response|B cell activation during immune response http://purl.obolibrary.org/obo/GO_0002312 GO:0051327 biolink:BiologicalProcess meiotic M phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle. go-plus.json M phase of meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051327 gocheck_do_not_annotate GO:2000797 biolink:BiologicalProcess regulation of amniotic stem cell differentiation Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000797 GO:2000798 biolink:BiologicalProcess negative regulation of amniotic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000798 GO:2000799 biolink:BiologicalProcess positive regulation of amniotic stem cell differentiation Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2000799 GO:0016958 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016958 CHEBI:41450 biolink:ChemicalSubstance gamma-carboxy-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41450 GO:0016959 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016959 GO:0016954 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016954 GO:2000790 biolink:BiologicalProcess regulation of mesenchymal cell proliferation involved in lung development Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. go-plus.json http://purl.obolibrary.org/obo/GO_2000790 GO:0016955 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016955 GO:2000791 biolink:BiologicalProcess negative regulation of mesenchymal cell proliferation involved in lung development Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. go-plus.json http://purl.obolibrary.org/obo/GO_2000791 GO:0016956 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016956 GO:2000792 biolink:BiologicalProcess positive regulation of mesenchymal cell proliferation involved in lung development Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. go-plus.json http://purl.obolibrary.org/obo/GO_2000792 GO:0016957 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016957 GO:0016950 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016950 GO:2000793 biolink:BiologicalProcess cell proliferation involved in heart valve development Any cell proliferation that is involved in heart valve development. go-plus.json cell proliferation of heart valve development|cell proliferation of cardiac valve development http://purl.obolibrary.org/obo/GO_2000793 CHEBI:90469 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-2-mono(long-chain acyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90469 chebi_ph7_3 GO:1905735 biolink:BiologicalProcess regulation of L-proline import across plasma membrane Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905735 GO:2000794 biolink:BiologicalProcess regulation of epithelial cell proliferation involved in lung morphogenesis Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000794 GO:0016951 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016951 GO:1905736 biolink:BiologicalProcess negative regulation of L-proline import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905736 CHEBI:16489 biolink:ChemicalSubstance lumazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16489 chebi_ph7_3 GO:0016952 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016952 GO:2000795 biolink:BiologicalProcess negative regulation of epithelial cell proliferation involved in lung morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2000795 GO:2000796 biolink:BiologicalProcess Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment. go-plus.json Notch-receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch-receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch signalling pathway involved in negative regulation of venous endothelial cell fate commitment|N signaling pathway involved in negative regulation of venous endothelial cell fate commitment http://purl.obolibrary.org/obo/GO_2000796 GO:1905737 biolink:BiologicalProcess positive regulation of L-proline import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905737 GO:0016953 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016953 CHEBI:16487 biolink:ChemicalSubstance benzyl cetraxate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16487 CHEBI:16488 biolink:ChemicalSubstance meso-2,6-diaminopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16488 CHEBI:16485 biolink:ChemicalSubstance 18-hydroxycorticosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16485 chebi_ph7_3 CHEBI:16486 biolink:ChemicalSubstance cyclopentanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16486 chebi_ph7_3 GO:0051320 biolink:BiologicalProcess S phase The cell cycle phase, following G1, during which DNA synthesis takes place. Wikipedia:S_phase go-plus.json S-phase http://purl.obolibrary.org/obo/GO_0051320 gocheck_do_not_annotate CHEBI:16483 biolink:ChemicalSubstance isonocardicin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_16483 GO:0002317 biolink:BiologicalProcess plasma cell differentiation The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. go-plus.json plasma cell development http://purl.obolibrary.org/obo/GO_0002317 GO:0051321 biolink:BiologicalProcess meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. Wikipedia:Meiosis go-plus.json meiosis http://purl.obolibrary.org/obo/GO_0051321 goslim_drosophila|goslim_yeast GO:0002318 biolink:BiologicalProcess myeloid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. go-plus.json http://purl.obolibrary.org/obo/GO_0002318 GO:0002319 biolink:BiologicalProcess memory B cell differentiation The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody. go-plus.json memory B lymphocyte differentiation|memory B-cell differentiation|memory B-lymphocyte differentiation|memory B cell development http://purl.obolibrary.org/obo/GO_0002319 CHEBI:16481 biolink:ChemicalSubstance N-(hydroxymethyl)urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_16481 chebi_ph7_3 CHEBI:90463 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-bis(long-chain acyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90463 chebi_ph7_3 CHEBI:16482 biolink:ChemicalSubstance naphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_16482 chebi_ph7_3 GO:0075302 biolink:BiologicalProcess regulation of basidiospore formation Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075302 GO:0051335 biolink:BiologicalProcess meiosis II nuclear membrane reassembly The reformation of the nuclear membrane during meiosis II. go-plus.json meiosis II nuclear envelope reassembly http://purl.obolibrary.org/obo/GO_0051335 GO:0051336 biolink:BiologicalProcess regulation of hydrolase activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. go-plus.json hydrolase regulator http://purl.obolibrary.org/obo/GO_0051336 GO:0075303 biolink:BiologicalProcess positive regulation of basidiospore formation Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075303 GO:0051333 biolink:BiologicalProcess meiotic nuclear membrane reassembly The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs. go-plus.json meiotic nuclear envelope reassembly http://purl.obolibrary.org/obo/GO_0051333 GO:0075304 biolink:BiologicalProcess negative regulation of basidiospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0075304 GO:0051334 biolink:BiologicalProcess meiosis I nuclear membrane reassembly The reformation of the nuclear membranes during meiosis I. go-plus.json meiosis I nuclear envelope reassembly http://purl.obolibrary.org/obo/GO_0051334 GO:0075305 biolink:BiologicalProcess obsolete modulation of growth or development of symbiont on or near host OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. go-plus.json modulation of growth or development of symbiont on or near host|modulation of growth or development of symbiont on or near host surface http://purl.obolibrary.org/obo/GO_0075305 CHEBI:90493 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-2-octoanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90493 chebi_ph7_3 GO:0075306 biolink:BiologicalProcess regulation of conidium formation Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. go-plus.json http://purl.obolibrary.org/obo/GO_0075306 GO:0051339 biolink:BiologicalProcess regulation of lyase activity Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. go-plus.json lyase regulator http://purl.obolibrary.org/obo/GO_0051339 GO:0075307 biolink:BiologicalProcess positive regulation of conidium formation Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. go-plus.json http://purl.obolibrary.org/obo/GO_0075307 GO:0051337 biolink:BiologicalProcess amitosis Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation. go-plus.json direct nuclear division|Remak nuclear division http://purl.obolibrary.org/obo/GO_0051337 GO:0075308 biolink:BiologicalProcess negative regulation of conidium formation Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. go-plus.json http://purl.obolibrary.org/obo/GO_0075308 GO:0075309 biolink:BiologicalProcess obsolete negative regulation of growth or development of symbiont on or near host surface OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. go-plus.json negative regulation of growth or development of symbiont on or near host surface http://purl.obolibrary.org/obo/GO_0075309 GO:0051338 biolink:BiologicalProcess regulation of transferase activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. go-plus.json transferase regulator http://purl.obolibrary.org/obo/GO_0051338 gocheck_do_not_manually_annotate GO:0016929 biolink:MolecularActivity SUMO-specific protease activity Catalysis of the hydrolysis of peptide or isopeptide bonds within SUMO, or between the SUMO and a larger protein to which it has been conjugated. go-plus.json SUSP|ULP http://purl.obolibrary.org/obo/GO_0016929 gocheck_do_not_manually_annotate GO:0016925 biolink:BiologicalProcess protein sumoylation The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. Wikipedia:SUMO_protein go-plus.json Smt3-protein conjugation|small ubiquitin-related protein 1 conjugation|Smt3p-protein conjugation|sumoylation|SUMO-protein conjugation|protein sumolation http://purl.obolibrary.org/obo/GO_0016925 GO:0016926 biolink:BiologicalProcess protein desumoylation The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. go-plus.json desumoylation|protein desumolation http://purl.obolibrary.org/obo/GO_0016926 GO:0016927 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016927 GO:1905750 biolink:BiologicalProcess negative regulation of endosome to plasma membrane protein transport Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport. go-plus.json downregulation of endosome to plasma membrane protein transport|down-regulation of endosome to plasma membrane protein transport|inhibition of endosome to plasma membrane protein transport|down regulation of endosome to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1905750 GO:1905751 biolink:BiologicalProcess positive regulation of endosome to plasma membrane protein transport Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport. go-plus.json up regulation of endosome to plasma membrane protein transport|activation of endosome to plasma membrane protein transport|up-regulation of endosome to plasma membrane protein transport|upregulation of endosome to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1905751 GO:0016928 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016928 GO:1905741 biolink:BiologicalProcess calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration. go-plus.json calcium ion transmembrane export from mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration http://purl.obolibrary.org/obo/GO_1905741 GO:0016921 biolink:MolecularActivity obsolete pyroglutamyl-peptidase II activity OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides. EC:3.4.19.6|MetaCyc:3.4.19.6-RXN go-plus.json pyroglutamyl peptidase II|thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity|TRH-DE activity|thyrotropin-releasing hormone degrading ectoenzyme activity|TRH-degrading ectoenzyme activity|thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity|TRH-specific aminopeptidase activity|thyrotropin-releasing hormone-degrading peptidase activity|pyroglutamyl aminopeptidase II activity|PAP-II activity|pyroglutamyl-peptidase II activity|thyrotropin-releasing factor pyroglutamate aminopeptidase activity|thyroliberinase activity|pyroglutamate aminopeptidase II http://purl.obolibrary.org/obo/GO_0016921 GO:1905742 biolink:CellularComponent Ras guanyl-nucleotide exchange factor complex A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1905742 GO:0016922 biolink:MolecularActivity nuclear receptor binding Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand. go-plus.json ligand-dependent nuclear receptor binding|nuclear hormone receptor binding|steroid hormone receptor binding|ligand-dependent nuclear receptor interactor activity http://purl.obolibrary.org/obo/GO_0016922 GO:0016923 biolink:MolecularActivity obsolete ligand-dependent thyroid hormone receptor interactor activity OBSOLETE. Ligand dependent interaction with the thyroid hormone receptor. go-plus.json ligand-dependent thyroid hormone receptor interactor activity|TRIP4 http://purl.obolibrary.org/obo/GO_0016923 GO:1905743 biolink:BiologicalProcess calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration. go-plus.json calcium ion transmembrane import into mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration http://purl.obolibrary.org/obo/GO_1905743 goslim_synapse GO:0016924 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016924 GO:1905744 biolink:BiologicalProcess regulation of mRNA cis splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome. go-plus.json regulation of nuclear mRNA cis splicing, via U2-type spliceosome|regulation of splicing|regulation of nuclear mRNA cis splicing, via spliceosome http://purl.obolibrary.org/obo/GO_1905744 GO:1905745 biolink:BiologicalProcess negative regulation of mRNA cis splicing, via spliceosome Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome. go-plus.json http://purl.obolibrary.org/obo/GO_1905745 GO:1905746 biolink:BiologicalProcess positive regulation of mRNA cis splicing, via spliceosome Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome. go-plus.json http://purl.obolibrary.org/obo/GO_1905746 GO:1905747 biolink:BiologicalProcess negative regulation of saliva secretion Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion. go-plus.json down-regulation of saliva secretion|negative regulation of salivation|down-regulation of salivation|downregulation of saliva secretion|downregulation of salivation|down regulation of saliva secretion|inhibition of saliva secretion|down regulation of salivation|inhibition of salivation http://purl.obolibrary.org/obo/GO_1905747 GO:1905748 biolink:BiologicalProcess hard palate morphogenesis The developmental process by which a hard palate is generated and organized. go-plus.json palatum durum morphogenesis http://purl.obolibrary.org/obo/GO_1905748 GO:0016920 biolink:MolecularActivity pyroglutamyl-peptidase activity Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein. EC:3.4.19.- go-plus.json http://purl.obolibrary.org/obo/GO_0016920 GO:1905749 biolink:BiologicalProcess regulation of endosome to plasma membrane protein transport Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport. go-plus.json http://purl.obolibrary.org/obo/GO_1905749 CHEBI:90499 biolink:ChemicalSubstance (7Z,10Z,13Z)-hexadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_90499 chebi_ph7_3 GO:0051331 biolink:BiologicalProcess meiotic G2 phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis. go-plus.json G2 phase of meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051331 gocheck_do_not_annotate GO:0051332 biolink:BiologicalProcess meiotic S phase The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle. go-plus.json S phase of meiotic cell cycle|S-phase of meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051332 gocheck_do_not_annotate GO:0075300 biolink:BiologicalProcess negative regulation of zygospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0075300 GO:0075301 biolink:BiologicalProcess obsolete cell differentiation involved in spore germination OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a specific cell type occurring during spore germination, the physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth. go-plus.json http://purl.obolibrary.org/obo/GO_0075301 GO:0051330 biolink:BiologicalProcess meiotic G1 phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis. go-plus.json G1 phase of meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051330 gocheck_do_not_annotate GO:0051346 biolink:BiologicalProcess negative regulation of hydrolase activity Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. go-plus.json down regulation of hydrolase activity|inhibition of hydrolase activity|hydrolase inhibitor|down-regulation of hydrolase activity|downregulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051346 GO:0051347 biolink:BiologicalProcess positive regulation of transferase activity Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. go-plus.json up-regulation of transferase activity|activation of transferase activity|up regulation of transferase activity|transferase activator|upregulation of transferase activity|stimulation of transferase activity http://purl.obolibrary.org/obo/GO_0051347 gocheck_do_not_manually_annotate GO:0051344 biolink:BiologicalProcess negative regulation of cyclic-nucleotide phosphodiesterase activity Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. go-plus.json 3',5' cyclic nucleotide phosphodiesterase inhibitor|down regulation of cyclic nucleotide phosphodiesterase activity|inhibition of cyclic nucleotide phosphodiesterase activity|phosphodiesterase inhibitor|negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase inhibitor|negative regulation of cyclic nucleotide phosphodiesterase activity|down-regulation of cyclic nucleotide phosphodiesterase activity|negative regulation of cAMP phosphodiesterase activity|negative regulation of cGMP phosphodiesterase activity|cAMP phosphodiesterase inhibitor|downregulation of cyclic nucleotide phosphodiesterase activity|negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0051344 CHEBI:90481 biolink:ChemicalSubstance 2-octanoyl-3-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90481 chebi_ph7_3 GO:0051345 biolink:BiologicalProcess positive regulation of hydrolase activity Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. go-plus.json upregulation of hydrolase activity|stimulation of hydrolase activity|up-regulation of hydrolase activity|activation of hydrolase activity|up regulation of hydrolase activity|hydrolase activator http://purl.obolibrary.org/obo/GO_0051345 GO:0051348 biolink:BiologicalProcess negative regulation of transferase activity Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. go-plus.json down-regulation of transferase activity|downregulation of transferase activity|down regulation of transferase activity|inhibition of transferase activity|transferase inhibitor http://purl.obolibrary.org/obo/GO_0051348 gocheck_do_not_manually_annotate UBERON:6001728 biolink:AnatomicalEntity insect larval tagma Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727). go-plus.json http://purl.obolibrary.org/obo/UBERON_6001728 UBERON:6001729 biolink:AnatomicalEntity insect larval segment Any segment that is part of some larva. go-plus.json http://purl.obolibrary.org/obo/UBERON_6001729 GO:0051349 biolink:BiologicalProcess positive regulation of lyase activity Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. go-plus.json up regulation of lyase activity|lyase activator|upregulation of lyase activity|stimulation of lyase activity|activation of lyase activity|up-regulation of lyase activity http://purl.obolibrary.org/obo/GO_0051349 GO:0016936 biolink:MolecularActivity galactoside binding Binding to a glycoside in which the sugar group is galactose. go-plus.json http://purl.obolibrary.org/obo/GO_0016936 goslim_chembl GO:1905760 biolink:CellularComponent post-anaphase array microtubule end Any microtubule end that is part of a post-anaphase array microtubule. go-plus.json microtubule end of microtubule of PAA|microtubule end of post-anaphase array microtubule|microtubule end of microtubule of post-anaphase array|microtubule end of neurotubule of post-anaphase microtubule array|microtubule end of microtubuli of PAA|microtubule end of microtubuli of post-anaphase array|microtubule end of microtubulus of PAA|microtubule end of microtubulus of post-anaphase array|microtubule end of neurotubule of PAA|microtubule end of microtubule of post-anaphase microtubule array|microtubule end of neurotubule of post-anaphase array|microtubule end of microtubuli of post-anaphase microtubule array|microtubule end of microtubulus of post-anaphase microtubule array http://purl.obolibrary.org/obo/GO_1905760 GO:0016937 biolink:MolecularActivity short-branched-chain-acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue. EC:1.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0016937 GO:1905761 biolink:MolecularActivity SCF ubiquitin ligase complex binding Binding to a SCF ubiquitin ligase complex. go-plus.json SCF complex substrate recognition subunit binding|SCF complex binding|CRL1 complex binding|Cul1-RING ubiquitin ligase complex binding|CDL1 complex binding|Skp1/Cul1/F-box protein complex binding|cullin-RING ligase 1 binding http://purl.obolibrary.org/obo/GO_1905761 GO:0016938 biolink:CellularComponent kinesin I complex A complex of two kinesin heavy chains and two kinesin light chains. go-plus.json http://purl.obolibrary.org/obo/GO_0016938 GO:1905762 biolink:MolecularActivity CCR4-NOT complex binding Binding to a CCR4-NOT complex. go-plus.json http://purl.obolibrary.org/obo/GO_1905762 GO:0016939 biolink:CellularComponent kinesin II complex A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0016939 GO:1905752 biolink:BiologicalProcess regulation of argininosuccinate synthase activity Any process that modulates the frequency, rate or extent of argininosuccinate synthase activity. go-plus.json regulation of citrulline--aspartate ligase activity|regulation of L-citrulline:L-aspartate ligase (AMP-forming)|regulation of argininosuccinate synthetase activity|regulation of arginosuccinate synthetase activity|regulation of arginine succinate synthetase activity|regulation of argininosuccinic acid synthetase activity http://purl.obolibrary.org/obo/GO_1905752 GO:0016932 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016932 GO:1905753 biolink:BiologicalProcess positive regulation of argininosuccinate synthase activity Any process that activates or increases the frequency, rate or extent of argininosuccinate synthase activity. go-plus.json up-regulation of citrulline--aspartate ligase activity|up-regulation of L-citrulline:L-aspartate ligase (AMP-forming)|up-regulation of argininosuccinate synthetase activity|up-regulation of arginine succinate synthetase activity|up regulation of argininosuccinate synthase activity|up regulation of argininosuccinic acid synthetase activity|activation of arginine succinate synthetase activity|positive regulation of argininosuccinic acid synthetase activity|activation of argininosuccinic acid synthetase activity|activation of argininosuccinate synthase activity|up-regulation of arginosuccinate synthetase activity|upregulation of citrulline--aspartate ligase activity|upregulation of argininosuccinate synthetase activity|upregulation of L-citrulline:L-aspartate ligase (AMP-forming)|positive regulation of arginine succinate synthetase activity|upregulation of arginosuccinate synthetase activity|up regulation of arginine succinate synthetase activity|up-regulation of argininosuccinic acid synthetase activity|up-regulation of argininosuccinate synthase activity|up regulation of citrulline--aspartate ligase activity|up regulation of argininosuccinate synthetase activity|up regulation of L-citrulline:L-aspartate ligase (AMP-forming)|activation of citrulline--aspartate ligase activity|positive regulation of citrulline--aspartate ligase activity|positive regulation of argininosuccinate synthetase activity|activation of L-citrulline:L-aspartate ligase (AMP-forming)|activation of argininosuccinate synthetase activity|positive regulation of L-citrulline:L-aspartate ligase (AMP-forming)|upregulation of argininosuccinate synthase activity|upregulation of argininosuccinic acid synthetase activity|up regulation of arginosuccinate synthetase activity|upregulation of arginine succinate synthetase activity|activation of arginosuccinate synthetase activity|positive regulation of arginosuccinate synthetase activity http://purl.obolibrary.org/obo/GO_1905753 GO:0016933 biolink:MolecularActivity extracellularly glycine-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. go-plus.json glycine receptor|extracellular-glycine-gated ion channel activity http://purl.obolibrary.org/obo/GO_0016933 GO:0016934 biolink:MolecularActivity extracellularly glycine-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. Reactome:R-HSA-975389 go-plus.json glycine-inhibited chloride channel activity|glycine receptor|extracellular-glycine-gated chloride channel activity http://purl.obolibrary.org/obo/GO_0016934 GO:1905754 biolink:CellularComponent ascospore-type prospore nucleus Any nucleus that is part of a ascospore-type prospore. go-plus.json nucleus of ascospore-type prospore|cell nucleus of ascospore-type prospore http://purl.obolibrary.org/obo/GO_1905754 GO:0016935 biolink:CellularComponent glycine-gated chloride channel complex A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0016935 GO:1905755 biolink:BiologicalProcess protein localization to cytoplasmic microtubule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. go-plus.json protein localisation to cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_1905755 GO:1905756 biolink:BiologicalProcess regulation of primary cell septum biogenesis Any process that modulates the frequency, rate or extent of primary cell septum biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905756 GO:1905757 biolink:BiologicalProcess negative regulation of primary cell septum biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905757 GO:1905758 biolink:BiologicalProcess positive regulation of primary cell septum biogenesis Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1905758 GO:0016930 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016930 GO:1905759 biolink:CellularComponent post-anaphase array microtubule Any microtubule that is part of a post-anaphase microtubule array. go-plus.json neurotubule of post-anaphase array|microtubuli of post-anaphase microtubule array|microtubule of PAA|microtubulus of PAA|microtubule of post-anaphase array|neurotubule of post-anaphase microtubule array|microtubuli of PAA|microtubulus of post-anaphase array|microtubuli of post-anaphase array|neurotubule of PAA|microtubule of post-anaphase microtubule array|microtubulus of post-anaphase microtubule array http://purl.obolibrary.org/obo/GO_1905759 GO:0016931 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016931 GO:0051342 biolink:BiologicalProcess regulation of cyclic-nucleotide phosphodiesterase activity Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. go-plus.json cAMP phosphodiesterase regulator|3',5' cyclic nucleotide phosphodiesterase regulator|regulation of cAMP phosphodiesterase activity|regulation of 3',5' cyclic nucleotide phosphodiesterase activity|regulation of cGMP phosphodiesterase activity|phosphodiesterase regulator|3',5'-cyclic-AMP phosphodiesterase regulator|regulation of cyclic nucleotide phosphodiesterase activity|regulation of 3',5'-cyclic-AMP phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0051342 GO:0051343 biolink:BiologicalProcess positive regulation of cyclic-nucleotide phosphodiesterase activity Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. go-plus.json positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity|positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity|upregulation of cyclic nucleotide phosphodiesterase activity|stimulation of cyclic nucleotide phosphodiesterase activity|up-regulation of cyclic nucleotide phosphodiesterase activity|activation of cyclic nucleotide phosphodiesterase activity|cAMP phosphodiesterase activator|positive regulation of cAMP phosphodiesterase activity|positive regulation of cGMP phosphodiesterase activity|positive regulation of cyclic nucleotide phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase activator|phosphodiesterase activator|up regulation of cyclic nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activator http://purl.obolibrary.org/obo/GO_0051343 GO:0051340 biolink:BiologicalProcess regulation of ligase activity Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. go-plus.json ligase regulator http://purl.obolibrary.org/obo/GO_0051340 GO:0051341 biolink:BiologicalProcess regulation of oxidoreductase activity Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. go-plus.json oxidoreductase regulator http://purl.obolibrary.org/obo/GO_0051341 CHEBI:145037 biolink:ChemicalSubstance hydroperoxy fatty ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_145037 CHEBI:145026 biolink:ChemicalSubstance L-psicose go-plus.json http://purl.obolibrary.org/obo/CHEBI_145026 chebi_ph7_3 GO:0002386 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002386 GO:0002387 biolink:BiologicalProcess immune response in gut-associated lymphoid tissue Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules. go-plus.json immune response in GALT http://purl.obolibrary.org/obo/GO_0002387 GO:0002388 biolink:BiologicalProcess immune response in Peyer's patch Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0002388 GO:0002389 biolink:BiologicalProcess tolerance induction in Peyer's patch Tolerance induction taking place in the Peyer's patches. go-plus.json http://purl.obolibrary.org/obo/GO_0002389 GO:0002382 biolink:BiologicalProcess regulation of tissue kallikrein-kinin cascade Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade. go-plus.json regulation of glandular kallikrein-kinin cascade http://purl.obolibrary.org/obo/GO_0002382 GO:0002383 biolink:BiologicalProcess immune response in brain or nervous system An immune response taking place in the brain or nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0002383 GO:0002384 biolink:BiologicalProcess hepatic immune response An immune response taking place in the liver. go-plus.json http://purl.obolibrary.org/obo/GO_0002384 GO:0002385 biolink:BiologicalProcess mucosal immune response An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract. go-plus.json immune response in MALT|immune response in mucosal-associated lymphoid tissue|immune response in urogenital tract http://purl.obolibrary.org/obo/GO_0002385 GO:0002380 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002380 GO:0002381 biolink:BiologicalProcess immunoglobulin production involved in immunoglobulin-mediated immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. go-plus.json immunoglobulin production involved in immunoglobulin mediated immune response|antibody secretion during immune response|immunoglobulin secretion involved in immune response|immunoglobulin production during immune response|immunoglobulin biosynthetic process involved in immune response|antibody production during immune response|immunoglobulin production involved in immune response http://purl.obolibrary.org/obo/GO_0002381 gocheck_do_not_annotate GO:0002397 biolink:BiologicalProcess MHC class I protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0002397 GO:0002398 biolink:BiologicalProcess MHC class Ib protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0002398 GO:0002399 biolink:BiologicalProcess MHC class II protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002399 GO:0002393 biolink:BiologicalProcess lysosomal enzyme production involved in inflammatory response The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels. go-plus.json production of lysosomal enzymes involved in acute inflammatory response|production of lysosomal enzymes involved in inflammatory response|lysosomal enzyme production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002393 GO:0002394 biolink:BiologicalProcess tolerance induction in gut-associated lymphoid tissue Tolerance induction taking place in the gut-associated lymphoid tissue (GALT). go-plus.json tolerance induction in GALT|oral tolerance http://purl.obolibrary.org/obo/GO_0002394 GO:0002395 biolink:BiologicalProcess immune response in nasopharyngeal-associated lymphoid tissue An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids. go-plus.json immune response in NALT http://purl.obolibrary.org/obo/GO_0002395 GO:0002396 biolink:BiologicalProcess MHC protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002396 GO:0002390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002390 GO:0002391 biolink:BiologicalProcess platelet activating factor production involved in inflammatory response The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. go-plus.json platelet activating factor production|platelet activating factor production involved in acute inflammatory response|platelet activating factor secretion|platelet activating factor secretion involved in acute inflammatory response|platelet activating factor secretion involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002391 GO:0002392 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002392 PR:000003652 biolink:Protein acrosin A protein that is a translation product of the human ACR gene or a 1:1 ortholog thereof. go-plus.json ACRS|ACR http://purl.obolibrary.org/obo/PR_000003652 GO:0002368 biolink:BiologicalProcess B cell cytokine production Any process that contributes to cytokine production by a B cell. go-plus.json B-cell cytokine production|B-lymphocyte cytokine production|B lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002368 gocheck_do_not_annotate GO:0002369 biolink:BiologicalProcess T cell cytokine production Any process that contributes to cytokine production by a T cell. go-plus.json T lymphocyte cytokine production|T-cell cytokine production|T-lymphocyte cytokine production http://purl.obolibrary.org/obo/GO_0002369 gocheck_do_not_annotate GO:0002364 biolink:BiologicalProcess NK T cell lineage commitment The process in which a pro-T cell becomes committed to becoming an NK T cell. go-plus.json natural killer T lymphocyte lineage commitment|NK T lymphocyte lineage commitment|natural killer T-lymphocyte lineage commitment|natural killer T-cell lineage commitment|NK T-lymphocyte lineage commitment|NK T-cell lineage commitment http://purl.obolibrary.org/obo/GO_0002364 GO:0002365 biolink:BiologicalProcess gamma-delta T cell lineage commitment The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell. go-plus.json gamma-delta T-lymphocyte lineage commitment|gamma-delta T-cell lineage commitment|gamma-delta T lymphocyte lineage commitment http://purl.obolibrary.org/obo/GO_0002365 NCBITaxon:38605 biolink:OrganismalEntity Didelphimorphia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_38605 GO:0002366 biolink:BiologicalProcess leukocyte activation involved in immune response A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. go-plus.json immune cell activation during immune response|leucocyte activation during immune response|leukocyte activation during immune response http://purl.obolibrary.org/obo/GO_0002366 GO:0002367 biolink:BiologicalProcess cytokine production involved in immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels. go-plus.json cytokine biosynthetic process involved in immune response|cytokine production during immune response|cytokine secretion involved in immune response|cytokine secretion during immune response http://purl.obolibrary.org/obo/GO_0002367 gocheck_do_not_annotate GO:0002360 biolink:BiologicalProcess T cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell. go-plus.json T lymphocyte lineage commitment|T-lymphocyte lineage commitment|T-cell lineage commitment http://purl.obolibrary.org/obo/GO_0002360 GO:0002361 biolink:BiologicalProcess CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell. go-plus.json CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T cell development http://purl.obolibrary.org/obo/GO_0002361 GO:0002362 biolink:BiologicalProcess CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell. go-plus.json CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T-cell lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte lineage commitment http://purl.obolibrary.org/obo/GO_0002362 GO:0002363 biolink:BiologicalProcess alpha-beta T cell lineage commitment The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell. go-plus.json alpha-beta T lymphocyte lineage commitment|alpha-beta T-lymphocyte lineage commitment|alpha-beta T-cell lineage commitment http://purl.obolibrary.org/obo/GO_0002363 CHEBI:90418 biolink:ChemicalSubstance N(6)-D-ribulosyl-L-lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_90418 chebi_ph7_3 GO:0002379 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002379 GO:0002375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002375 GO:0002376 biolink:BiologicalProcess immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. Wikipedia:Immune_system go-plus.json http://purl.obolibrary.org/obo/GO_0002376 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_pir|goslim_generic GO:0002377 biolink:BiologicalProcess immunoglobulin production The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json antibody production|immunoglobulin biosynthetic process|immunoglobulin secretion http://purl.obolibrary.org/obo/GO_0002377 gocheck_do_not_annotate GO:0002378 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002378 GO:0002371 biolink:BiologicalProcess dendritic cell cytokine production Any process that contributes to cytokine production by a dendritic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002371 gocheck_do_not_annotate GO:0002372 biolink:BiologicalProcess myeloid dendritic cell cytokine production Any process that contributes to cytokine production by a myeloid dendritic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002372 gocheck_do_not_annotate GO:0002373 biolink:BiologicalProcess plasmacytoid dendritic cell cytokine production Any process that contributes to cytokine production by a plasmacytoid dendritic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002373 gocheck_do_not_annotate GO:0002374 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002374 GO:0002370 biolink:BiologicalProcess natural killer cell cytokine production Any process that contributes to cytokine production by a natural killer cell. go-plus.json NK cell cytokine production http://purl.obolibrary.org/obo/GO_0002370 gocheck_do_not_annotate CHEBI:90409 biolink:ChemicalSubstance 5-hydroxymethyluridine-2'-deoxy-5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90409 chebi_ph7_3 CHEBI:89417 biolink:ChemicalSubstance 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_89417 CHEBI:90400 biolink:ChemicalSubstance alpha-D-GalNAc-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90400 chebi_ph7_3 GO:0110137 biolink:BiologicalProcess regulation of imaginal disc-derived leg joint morphogenesis Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0110137 GO:0110138 biolink:BiologicalProcess positive regulation of imaginal disc-derived leg joint morphogenesis Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110138 GO:0110135 biolink:BiologicalProcess Norrin signaling pathway The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state. go-plus.json http://purl.obolibrary.org/obo/GO_0110135 GO:0110136 biolink:BiologicalProcess protein-RNA complex remodeling The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex. go-plus.json http://purl.obolibrary.org/obo/GO_0110136 GO:0110133 biolink:BiologicalProcess negative regulation of CRISPR-cas system Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system. go-plus.json http://purl.obolibrary.org/obo/GO_0110133 GO:0110134 biolink:BiologicalProcess meiotic drive A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0110134 goslim_pombe GO:0110131 biolink:CellularComponent Aim21-Tda2 complex A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables. go-plus.json Aim21/Tda2 complex http://purl.obolibrary.org/obo/GO_0110131 GO:0110132 biolink:BiologicalProcess regulation of CRISPR-cas system Any process that modulates the frequency, rate or extent of a CRISPR-cas system. go-plus.json http://purl.obolibrary.org/obo/GO_0110132 GO:0110130 biolink:MolecularActivity ribitol-5-phosphatase activity Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate. RHEA:47648 go-plus.json http://purl.obolibrary.org/obo/GO_0110130 GO:0110139 biolink:BiologicalProcess negative regulation of imaginal disc-derived leg joint morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110139 GO:0110148 biolink:BiologicalProcess biomineralization The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products. Wikipedia:Biomineralization go-plus.json mineralization|biomineral formation|biomineralisation|mineralisation http://purl.obolibrary.org/obo/GO_0110148 GO:0110149 biolink:BiologicalProcess regulation of biomineralization Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. go-plus.json regulation of biomineralisation|regulation of mineralisation|regulation of mineralization|regulation of biomineral formation http://purl.obolibrary.org/obo/GO_0110149 GO:0110146 biolink:CellularComponent magnetosome membrane The lipid bilayer surrounding a magnetosome. go-plus.json http://purl.obolibrary.org/obo/GO_0110146 GO:0110147 biolink:BiologicalProcess protein maturation by nickel ion transfer A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation. go-plus.json http://purl.obolibrary.org/obo/GO_0110147 GO:0110144 biolink:CellularComponent obsolete magnetosome part OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0110144 GO:0110145 biolink:CellularComponent magnetosome lumen The volume enclosed by the membrane of a magnetosome. go-plus.json http://purl.obolibrary.org/obo/GO_0110145 GO:0110142 biolink:CellularComponent ubiquinone biosynthesis complex The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K. go-plus.json Ubi complex|CoQ metabolon http://purl.obolibrary.org/obo/GO_0110142 GO:0110143 biolink:CellularComponent magnetosome A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0110143 GO:0110140 biolink:BiologicalProcess flagellum attachment zone organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species. go-plus.json FAZ organization|flagellum attachment zone organisation http://purl.obolibrary.org/obo/GO_0110140 GO:0110141 biolink:BiologicalProcess L-glutamate import into mitochondrion The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0110141 GO:0110159 biolink:BiologicalProcess regulation of mitotic spindle formation (spindle phase one) Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one). go-plus.json http://purl.obolibrary.org/obo/GO_0110159 GO:0110157 biolink:CellularComponent reelin complex An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain. go-plus.json http://purl.obolibrary.org/obo/GO_0110157 GO:0110158 biolink:CellularComponent calpain complex A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate. go-plus.json M-calpain|mu-calpain http://purl.obolibrary.org/obo/GO_0110158 GO:0110155 biolink:BiologicalProcess NAD-cap decapping Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0110155 GO:0110156 biolink:BiologicalProcess methylguanosine-cap decapping Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0110156 UBERON:0008281 biolink:AnatomicalEntity tooth bud A knoblike tooth primordium that develops into the mature tooth and consists of enamel organ, dental papilla, and dental sac enclosing them. go-plus.json dental germ|dental bud|tooth germ http://purl.obolibrary.org/obo/UBERON_0008281 GO:0110153 biolink:MolecularActivity RNA NAD-cap (NMN-forming) hydrolase activity Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+). RHEA:60876 go-plus.json http://purl.obolibrary.org/obo/GO_0110153 GO:0110154 biolink:BiologicalProcess RNA decapping Cleavage of the 5'-cap of an RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0110154 NCBITaxon:544448 biolink:OrganismalEntity Tenericutes go-plus.json Mollicutaeota|Mollicutota http://purl.obolibrary.org/obo/NCBITaxon_544448 GO:0110151 biolink:BiologicalProcess positive regulation of biomineralization Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. go-plus.json positive regulation of mineralisation|positive regulation of mineralization|positive regulation of biomineral formation|positive regulation of biomineralisation http://purl.obolibrary.org/obo/GO_0110151 GO:0110152 biolink:MolecularActivity RNA NAD-cap (NAD-forming) hydrolase activity Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+). RHEA:60880 go-plus.json http://purl.obolibrary.org/obo/GO_0110152 GO:0110150 biolink:BiologicalProcess negative regulation of biomineralization Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. go-plus.json negative regulation of mineralisation|negative regulation of mineralization|negative regulation of biomineral formation|negative regulation of biomineralisation http://purl.obolibrary.org/obo/GO_0110150 GO:0110166 biolink:BiologicalProcess DNA synthesis involved in mitochondrial DNA replication Any DNA biosynthetic process that is involved in mitochondrial DNA replication. go-plus.json DNA biosynthetic process involved in mitochondrial DNA replication http://purl.obolibrary.org/obo/GO_0110166 GO:0110164 biolink:BiologicalProcess positive regulation of mitotic spindle elongation (spindle phase three) Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three). go-plus.json http://purl.obolibrary.org/obo/GO_0110164 GO:0110165 biolink:CellularComponent cellular anatomical entity A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0110165 GO:0110162 biolink:BiologicalProcess regulation of mitotic spindle elongation (spindle phase three) Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three). go-plus.json http://purl.obolibrary.org/obo/GO_0110162 GO:0110163 biolink:BiologicalProcess negative regulation of mitotic spindle elongation (spindle phase three) Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three). go-plus.json http://purl.obolibrary.org/obo/GO_0110163 GO:0110160 biolink:BiologicalProcess negative regulation of mitotic spindle formation (spindle phase one) Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one). go-plus.json http://purl.obolibrary.org/obo/GO_0110160 GO:0110161 biolink:BiologicalProcess positive regulation of mitotic spindle formation (spindle phase one) Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one). go-plus.json http://purl.obolibrary.org/obo/GO_0110161 GO:0110104 biolink:BiologicalProcess mRNA alternative polyadenylation The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals). go-plus.json http://purl.obolibrary.org/obo/GO_0110104 GO:0110105 biolink:BiologicalProcess mRNA cleavage and polyadenylation specificity factor complex assembly The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex. go-plus.json http://purl.obolibrary.org/obo/GO_0110105 GO:0110102 biolink:BiologicalProcess ribulose bisphosphate carboxylase complex assembly The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex. go-plus.json rubisco assembly|RuBisCO assembly http://purl.obolibrary.org/obo/GO_0110102 GO:0110103 biolink:CellularComponent RNA polymerase II termination complex A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end. go-plus.json TXT complex http://purl.obolibrary.org/obo/GO_0110103 GO:0110100 biolink:BiologicalProcess spindle pole body separation The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble. go-plus.json http://purl.obolibrary.org/obo/GO_0110100 gocheck_do_not_manually_annotate GO:0110101 biolink:BiologicalProcess L-valine transmembrane import into vacuole The directed movement of L-valine into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0110101 CHEBI:145078 biolink:ChemicalSubstance 3-oxo aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_145078 GO:0110108 biolink:BiologicalProcess positive regulation of imaginal disc-derived wing vein specification Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification. go-plus.json http://purl.obolibrary.org/obo/GO_0110108 GO:0110109 biolink:BiologicalProcess negative regulation of imaginal disc-derived wing vein specification Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification. go-plus.json http://purl.obolibrary.org/obo/GO_0110109 GO:0110107 biolink:BiologicalProcess regulation of imaginal disc-derived wing vein specification Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification. go-plus.json http://purl.obolibrary.org/obo/GO_0110107 GO:0110115 biolink:CellularComponent Cdr2 medial cortical node complex A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase. go-plus.json interphase cortical node|interphase node http://purl.obolibrary.org/obo/GO_0110115 GO:0110116 biolink:BiologicalProcess regulation of compound eye photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0110116 GO:0110113 biolink:BiologicalProcess positive regulation of lipid transporter activity Any process that increases the frequency, rate, or extent of lipid transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_0110113 GO:0110114 biolink:BiologicalProcess negative regulation of lipid transporter activity Any process that decreases the frequency, rate, or extent of lipid transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_0110114 GO:0110111 biolink:BiologicalProcess negative regulation of animal organ morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110111 GO:0110112 biolink:BiologicalProcess regulation of lipid transporter activity Any process that modulates the frequency, rate, or extent of lipid transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_0110112 GO:0110110 biolink:BiologicalProcess positive regulation of animal organ morphogenesis Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0110110 GO:0110119 biolink:BiologicalProcess positive regulation of very-low-density lipoprotein particle clearance Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance. go-plus.json http://purl.obolibrary.org/obo/GO_0110119 GO:0110117 biolink:BiologicalProcess positive regulation of compound eye photoreceptor cell differentiation Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0110117 GO:0110118 biolink:BiologicalProcess negative regulation of compound eye photoreceptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0110118 GO:0110126 biolink:BiologicalProcess phloem loading The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink. go-plus.json http://purl.obolibrary.org/obo/GO_0110126 GO:0110127 biolink:BiologicalProcess phloem unloading The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0110127 GO:0110124 biolink:BiologicalProcess positive regulation of myotube cell migration Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0110124 GO:0110125 biolink:BiologicalProcess negative regulation of myotube cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0110125 GO:0110122 biolink:BiologicalProcess myotube cell migration The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0110122 GO:0110123 biolink:BiologicalProcess regulation of myotube cell migration Any process that modulates the frequency, rate or extent of myotube cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0110123 GO:0110120 biolink:BiologicalProcess gamma-tubulin complex localization to nuclear side of mitotic spindle pole body Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0110120 GO:0110121 biolink:BiologicalProcess gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0110121 GO:0110128 biolink:BiologicalProcess phloem sucrose unloading The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0110128 GO:0110129 biolink:CellularComponent SHREC2 complex A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2. go-plus.json http://purl.obolibrary.org/obo/GO_0110129 GO:0051478 biolink:BiologicalProcess mannosylglycerate metabolic process The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms. go-plus.json mannosylglycerate metabolism http://purl.obolibrary.org/obo/GO_0051478 GO:2000629 biolink:BiologicalProcess negative regulation of miRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process. go-plus.json negative regulation of microRNA metabolic process http://purl.obolibrary.org/obo/GO_2000629 GO:0002500 biolink:BiologicalProcess proteolysis within lysosome associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation. go-plus.json lysosomal proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002500 GO:0002501 biolink:BiologicalProcess peptide antigen assembly with MHC protein complex The binding of a peptide to the antigen binding groove of an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002501 CHEBI:90392 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90392 chebi_ph7_3 GO:0051479 biolink:BiologicalProcess mannosylglycerate biosynthetic process The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms. go-plus.json mannosylglycerate anabolism|mannosylglycerate biosynthesis|mannosylglycerate synthesis|mannosylglycerate formation http://purl.obolibrary.org/obo/GO_0051479 GO:0002502 biolink:BiologicalProcess peptide antigen assembly with MHC class I protein complex The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0002502 GO:0051476 biolink:BiologicalProcess mannosylglycerate transport The directed movement of mannosylglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051476 GO:0051477 biolink:MolecularActivity mannosylglycerate transmembrane transporter activity Enables the transfer of a mannosylglycerate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0051477 GO:0002503 biolink:BiologicalProcess peptide antigen assembly with MHC class II protein complex The binding of a peptide to the antigen binding groove of an MHC class II protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002503 IAO:0000228 biolink:OntologyClass term imported go-plus.json http://purl.obolibrary.org/obo/IAO_0000228 CHEBI:90390 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90390 chebi_ph7_3 IAO:0000229 biolink:OntologyClass term split go-plus.json http://purl.obolibrary.org/obo/IAO_0000229 GO:2000621 biolink:BiologicalProcess regulation of DNA replication termination Any process that modulates the frequency, rate or extent of DNA replication termination. go-plus.json http://purl.obolibrary.org/obo/GO_2000621 GO:2000622 biolink:BiologicalProcess regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. go-plus.json regulation of mRNA degradation, nonsense-mediated decay|regulation of nonsense-mediated mRNA decay|regulation of mRNA catabolism, nonsense-mediated|regulation of nuclear mRNA catabolic process, nonsense-mediated decay|regulation of mRNA catabolic process, nonsense-mediated|regulation of mRNA breakdown, nonsense-mediated decay http://purl.obolibrary.org/obo/GO_2000622 GO:2000623 biolink:BiologicalProcess negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. go-plus.json negative regulation of mRNA catabolism, nonsense-mediated|negative regulation of mRNA breakdown, nonsense-mediated decay|negative regulation of mRNA degradation, nonsense-mediated decay|negative regulation of nonsense-mediated mRNA decay|negative regulation of mRNA catabolic process, nonsense-mediated|negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay http://purl.obolibrary.org/obo/GO_2000623 GO:2000624 biolink:BiologicalProcess positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. go-plus.json positive regulation of nonsense-mediated mRNA decay|positive regulation of mRNA breakdown, nonsense-mediated decay|positive regulation of mRNA catabolism, nonsense-mediated|positive regulation of mRNA degradation, nonsense-mediated decay|positive regulation of mRNA catabolic process, nonsense-mediated|positive regulation of nuclear mRNA catabolic process, nonsense-mediated decay http://purl.obolibrary.org/obo/GO_2000624 GO:2000625 biolink:BiologicalProcess regulation of miRNA catabolic process Any process that modulates the frequency, rate or extent of miRNA catabolic process. go-plus.json regulation of microRNA catabolic process http://purl.obolibrary.org/obo/GO_2000625 GO:2000626 biolink:BiologicalProcess negative regulation of miRNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process. go-plus.json negative regulation of microRNA catabolic process http://purl.obolibrary.org/obo/GO_2000626 GO:1905650 biolink:BiologicalProcess positive regulation of shell calcification Any process that activates or increases the frequency, rate or extent of shell calcification. go-plus.json up regulation of shell calcification|activation of shell calcification|up-regulation of shell calcification|upregulation of shell calcification http://purl.obolibrary.org/obo/GO_1905650 GO:1905651 biolink:BiologicalProcess regulation of artery morphogenesis Any process that modulates the frequency, rate or extent of artery morphogenesis. go-plus.json regulation of arteriogenesis|regulation of arterial morphogenesis http://purl.obolibrary.org/obo/GO_1905651 GO:2000627 biolink:BiologicalProcess positive regulation of miRNA catabolic process Any process that activates or increases the frequency, rate or extent of miRNA catabolic process. go-plus.json positive regulation of microRNA catabolic process http://purl.obolibrary.org/obo/GO_2000627 GO:1905652 biolink:BiologicalProcess negative regulation of artery morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. go-plus.json down-regulation of artery morphogenesis|downregulation of arteriogenesis|down regulation of arteriogenesis|down-regulation of arterial morphogenesis|negative regulation of arterial morphogenesis|inhibition of arteriogenesis|downregulation of artery morphogenesis|down regulation of artery morphogenesis|inhibition of artery morphogenesis|downregulation of arterial morphogenesis|down regulation of arterial morphogenesis|inhibition of arterial morphogenesis|negative regulation of arteriogenesis|down-regulation of arteriogenesis http://purl.obolibrary.org/obo/GO_1905652 GO:2000628 biolink:BiologicalProcess regulation of miRNA metabolic process Any process that modulates the frequency, rate or extent of miRNA metabolic process. go-plus.json regulation of microRNA metabolic process http://purl.obolibrary.org/obo/GO_2000628 GO:1905642 biolink:BiologicalProcess negative regulation of DNA methylation Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation. go-plus.json down regulation of DNA methylation|downregulation of DNA methylation|down-regulation of DNA methylation|inhibition of DNA methylation http://purl.obolibrary.org/obo/GO_1905642 GO:1905643 biolink:BiologicalProcess positive regulation of DNA methylation Any process that activates or increases the frequency, rate or extent of DNA methylation. go-plus.json up regulation of DNA methylation|activation of DNA methylation|up-regulation of DNA methylation|upregulation of DNA methylation http://purl.obolibrary.org/obo/GO_1905643 GO:1905644 biolink:BiologicalProcess regulation of FACT complex assembly Any process that modulates the frequency, rate or extent of FACT complex assembly. go-plus.json regulation of Facilitates chromatin transcription complex assembly|regulation of Facilitates chromatin transcription complex formation|regulation of FACT complex formation http://purl.obolibrary.org/obo/GO_1905644 GO:1905645 biolink:BiologicalProcess negative regulation of FACT complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly. go-plus.json inhibition of FACT complex formation|down regulation of Facilitates chromatin transcription complex formation|down regulation of Facilitates chromatin transcription complex assembly|inhibition of Facilitates chromatin transcription complex assembly|down regulation of FACT complex assembly|downregulation of Facilitates chromatin transcription complex formation|downregulation of FACT complex assembly|down-regulation of Facilitates chromatin transcription complex formation|negative regulation of Facilitates chromatin transcription complex formation|down-regulation of FACT complex assembly|negative regulation of FACT complex formation|down-regulation of FACT complex formation|inhibition of Facilitates chromatin transcription complex formation|negative regulation of Facilitates chromatin transcription complex assembly|down-regulation of Facilitates chromatin transcription complex assembly|inhibition of FACT complex assembly|downregulation of FACT complex formation|downregulation of Facilitates chromatin transcription complex assembly|down regulation of FACT complex formation http://purl.obolibrary.org/obo/GO_1905645 UBERON:0008229 biolink:AnatomicalEntity craniocervical region musculature Musculature system of the pharyngeal and head regions. go-plus.json head or neck muscle|head or neck muscle|head muscles http://purl.obolibrary.org/obo/UBERON_0008229 CHEBI:9889 biolink:ChemicalSubstance urea-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_9889 GO:1905646 biolink:BiologicalProcess positive regulation of FACT complex assembly Any process that activates or increases the frequency, rate or extent of FACT complex assembly. go-plus.json upregulation of FACT complex assembly|upregulation of FACT complex formation|upregulation of Facilitates chromatin transcription complex assembly|up regulation of Facilitates chromatin transcription complex formation|activation of Facilitates chromatin transcription complex formation|positive regulation of Facilitates chromatin transcription complex formation|up regulation of FACT complex assembly|activation of FACT complex formation|up-regulation of FACT complex formation|activation of FACT complex assembly|activation of Facilitates chromatin transcription complex assembly|up-regulation of Facilitates chromatin transcription complex assembly|up-regulation of Facilitates chromatin transcription complex formation|positive regulation of FACT complex formation|up-regulation of FACT complex assembly|up regulation of FACT complex formation|positive regulation of Facilitates chromatin transcription complex assembly|up regulation of Facilitates chromatin transcription complex assembly|upregulation of Facilitates chromatin transcription complex formation http://purl.obolibrary.org/obo/GO_1905646 CHEBI:16458 biolink:ChemicalSubstance triacetate lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16458 chebi_ph7_3 CHEBI:41425 biolink:ChemicalSubstance (7R)-7-(4-carboxybutanamido)cephalosporanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41425 GO:1905647 biolink:BiologicalProcess proline import across plasma membrane The directed movement of proline from outside of a cell into the cytoplasmic compartment. go-plus.json proline import into cell http://purl.obolibrary.org/obo/GO_1905647 CHEBI:16459 biolink:ChemicalSubstance pentanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16459 chebi_ph7_3 GO:1905648 biolink:BiologicalProcess regulation of shell calcification Any process that modulates the frequency, rate or extent of shell calcification. go-plus.json http://purl.obolibrary.org/obo/GO_1905648 CHEBI:16456 biolink:ChemicalSubstance 2-(2-hydroxyacyl)sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16456 chebi_ph7_3 GO:2000620 biolink:BiologicalProcess positive regulation of histone H4-K16 acetylation Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation. go-plus.json positive regulation of histone H4 acetylation at K16 http://purl.obolibrary.org/obo/GO_2000620 GO:1905649 biolink:BiologicalProcess negative regulation of shell calcification Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification. go-plus.json down-regulation of shell calcification|inhibition of shell calcification|down regulation of shell calcification|downregulation of shell calcification http://purl.obolibrary.org/obo/GO_1905649 CHEBI:16457 biolink:ChemicalSubstance S,S-dimethyl-beta-propiothetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16457 chebi_ph7_3 CHEBI:16454 biolink:ChemicalSubstance pantothenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16454 chebi_ph7_3 GO:0051470 biolink:BiologicalProcess ectoine transport The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0051470 GO:0002508 biolink:BiologicalProcess central tolerance induction Tolerance induction in the central lymphoid organs: the thymus and bone marrow. go-plus.json http://purl.obolibrary.org/obo/GO_0002508 CHEBI:16455 biolink:ChemicalSubstance 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16455 chebi_ph7_3 GO:0051471 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051471 GO:0002509 biolink:BiologicalProcess central tolerance induction to self antigen Tolerance induction in the central lymphoid organs directed at self antigens. go-plus.json http://purl.obolibrary.org/obo/GO_0002509 CHEBI:16452 biolink:ChemicalSubstance oxaloacetate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16452 chebi_ph7_3 CHEBI:16453 biolink:ChemicalSubstance 1,4,5,6-tetrahydro-6-oxonicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16453 CHEBI:16450 biolink:ChemicalSubstance 2'-deoxyuridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16450 chebi_ph7_3 GO:0051474 biolink:MolecularActivity glucosylglycerol transmembrane transporter activity Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol. go-plus.json http://purl.obolibrary.org/obo/GO_0051474 IAO:0000233 biolink:OntologyClass term tracker item IAO:0000233 go-plus.json http://purl.obolibrary.org/obo/IAO_0000233 GO:0002504 biolink:BiologicalProcess antigen processing and presentation of peptide or polysaccharide antigen via MHC class II The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex. go-plus.json peptide or polysaccharide antigen processing and presentation of via MHC class II http://purl.obolibrary.org/obo/GO_0002504 GO:0051475 biolink:BiologicalProcess glucosylglycerol transport The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0051475 GO:0002505 biolink:BiologicalProcess antigen processing and presentation of polysaccharide antigen via MHC class II The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex. go-plus.json polysaccharide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002505 CHEBI:90396 biolink:ChemicalSubstance (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_90396 GO:0051472 biolink:BiologicalProcess glucosylglycerol metabolic process The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol. go-plus.json glucosylglycerol metabolism http://purl.obolibrary.org/obo/GO_0051472 CHEBI:90397 biolink:ChemicalSubstance 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90397 chebi_ph7_3 GO:0002506 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002506 GO:0051473 biolink:BiologicalProcess glucosylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol. go-plus.json glucosylglycerol biosynthesis|glucosylglycerol anabolism|glucosylglycerol synthesis|glucosylglycerol formation http://purl.obolibrary.org/obo/GO_0051473 CHEBI:90398 biolink:ChemicalSubstance (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90398 chebi_ph7_3 GO:0002507 biolink:BiologicalProcess tolerance induction A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it. go-plus.json http://purl.obolibrary.org/obo/GO_0002507 GO:0002511 biolink:BiologicalProcess central B cell receptor editing Receptor editing occurring in B cells in the bone marrow. go-plus.json central B-lymphocyte receptor editing|central B-cell receptor editing|central B lymphocyte receptor editing http://purl.obolibrary.org/obo/GO_0002511 GO:0051489 biolink:BiologicalProcess regulation of filopodium assembly Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. go-plus.json regulation of filopodia formation|regulation of filopodium formation|regulation of filopodia biosynthesis http://purl.obolibrary.org/obo/GO_0051489 CHEBI:90380 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90380 chebi_ph7_3 GO:0002512 biolink:BiologicalProcess central T cell tolerance induction Tolerance induction of T cells in the thymus. go-plus.json central T lymphocyte tolerance induction|central T-cell tolerance induction|central T-lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002512 CHEBI:90381 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90381 chebi_ph7_3 GO:0051487 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051487 GO:0002513 biolink:BiologicalProcess tolerance induction to self antigen Tolerance induction directed at self antigens. go-plus.json http://purl.obolibrary.org/obo/GO_0002513 GO:0002514 biolink:BiologicalProcess B cell tolerance induction A process involving any mechanism for tolerance induction in B cells. go-plus.json B lymphocyte tolerance induction|B-cell tolerance induction|B-lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002514 GO:0051488 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051488 CHEBI:90383 biolink:ChemicalSubstance alpha-Neu5Gc-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90383 chebi_ph7_3 GO:0002510 biolink:BiologicalProcess central B cell tolerance induction Tolerance induction of B cells in the bone marrow. go-plus.json central B-cell tolerance induction|central B-lymphocyte tolerance induction|central B lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002510 GO:2000632 biolink:BiologicalProcess negative regulation of pre-miRNA processing Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing. go-plus.json negative regulation of pre-microRNA processing http://purl.obolibrary.org/obo/GO_2000632 GO:2000633 biolink:BiologicalProcess positive regulation of pre-miRNA processing Any process that activates or increases the frequency, rate or extent of pre-microRNA processing. go-plus.json positive regulation of pre-microRNA processing http://purl.obolibrary.org/obo/GO_2000633 GO:2000634 biolink:BiologicalProcess regulation of primary miRNA processing Any process that modulates the frequency, rate or extent of primary microRNA processing. go-plus.json regulation of pri-miRNA processing|regulation of primary microRNA processing http://purl.obolibrary.org/obo/GO_2000634 GO:2000635 biolink:BiologicalProcess negative regulation of primary miRNA processing Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing. go-plus.json negative regulation of primary microRNA processing|negative regulation of pri-miRNA processing http://purl.obolibrary.org/obo/GO_2000635 GO:1905660 biolink:BiologicalProcess mitotic checkpoint complex assembly The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex. go-plus.json mitotic checkpoint complex formation|MCC formation|MCC assembly http://purl.obolibrary.org/obo/GO_1905660 GO:2000636 biolink:BiologicalProcess positive regulation of primary miRNA processing Any process that activates or increases the frequency, rate or extent of primary microRNA processing. go-plus.json positive regulation of primary microRNA processing|positive regulation of pri-miRNA processing http://purl.obolibrary.org/obo/GO_2000636 GO:2000637 biolink:BiologicalProcess positive regulation of gene silencing by miRNA Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA. go-plus.json positive regulation of gene silencing by microRNA|positive regulation of microRNA-mediated gene silencing|positive regulation of miRNA-mediated gene silencing http://purl.obolibrary.org/obo/GO_2000637 GO:1905661 biolink:BiologicalProcess regulation of telomerase RNA reverse transcriptase activity Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity. go-plus.json regulation of telomerase, catalyst http://purl.obolibrary.org/obo/GO_1905661 GO:1905662 biolink:BiologicalProcess negative regulation of telomerase RNA reverse transcriptase activity Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity. go-plus.json down-regulation of telomerase, catalyst|negative regulation of telomerase, catalyst|downregulation of telomerase, catalyst|down regulation of telomerase RNA reverse transcriptase activity|down regulation of telomerase, catalyst|downregulation of telomerase RNA reverse transcriptase activity|inhibition of telomerase, catalyst|down-regulation of telomerase RNA reverse transcriptase activity|inhibition of telomerase RNA reverse transcriptase activity http://purl.obolibrary.org/obo/GO_1905662 GO:2000638 biolink:BiologicalProcess regulation of SREBP signaling pathway Any process that modulates the frequency, rate or extent of the SREBP signaling pathway. go-plus.json regulation of SREBP-mediated signaling pathway|regulation of SREBP-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000638 GO:1905663 biolink:BiologicalProcess positive regulation of telomerase RNA reverse transcriptase activity Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity. go-plus.json positive regulation of telomerase, catalyst|up regulation of telomerase, catalyst|upregulation of telomerase RNA reverse transcriptase activity|upregulation of telomerase, catalyst|up regulation of telomerase RNA reverse transcriptase activity|activation of telomerase RNA reverse transcriptase activity|up-regulation of telomerase, catalyst|activation of telomerase, catalyst|up-regulation of telomerase RNA reverse transcriptase activity http://purl.obolibrary.org/obo/GO_1905663 GO:2000639 biolink:BiologicalProcess negative regulation of SREBP signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway. go-plus.json negative regulation of SREBP-mediated signaling pathway|negative regulation of SREBP-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2000639 GO:1905653 biolink:BiologicalProcess positive regulation of artery morphogenesis Any process that activates or increases the frequency, rate or extent of artery morphogenesis. go-plus.json up-regulation of arterial morphogenesis|up regulation of arteriogenesis|activation of arterial morphogenesis|up regulation of artery morphogenesis|upregulation of arteriogenesis|positive regulation of arterial morphogenesis|up regulation of arterial morphogenesis|upregulation of artery morphogenesis|up-regulation of arteriogenesis|activation of arteriogenesis|upregulation of arterial morphogenesis|up-regulation of artery morphogenesis|activation of artery morphogenesis|positive regulation of arteriogenesis http://purl.obolibrary.org/obo/GO_1905653 GO:1905654 biolink:BiologicalProcess regulation of artery smooth muscle contraction Any process that modulates the frequency, rate or extent of artery smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_1905654 GO:1905655 biolink:BiologicalProcess negative regulation of artery smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction. go-plus.json down-regulation of artery smooth muscle contraction|downregulation of artery smooth muscle contraction|down regulation of artery smooth muscle contraction|inhibition of artery smooth muscle contraction http://purl.obolibrary.org/obo/GO_1905655 CHEBI:16449 biolink:ChemicalSubstance alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16449 GO:1905656 biolink:BiologicalProcess positive regulation of artery smooth muscle contraction Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction. go-plus.json up-regulation of artery smooth muscle contraction|activation of artery smooth muscle contraction|up regulation of artery smooth muscle contraction|upregulation of artery smooth muscle contraction http://purl.obolibrary.org/obo/GO_1905656 GO:1905657 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905657 GO:1905658 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905658 GO:2000630 biolink:BiologicalProcess positive regulation of miRNA metabolic process Any process that activates or increases the frequency, rate or extent of miRNA metabolic process. go-plus.json positive regulation of microRNA metabolic process http://purl.obolibrary.org/obo/GO_2000630 GO:1905659 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1905659 CHEBI:16445 biolink:ChemicalSubstance stipitatonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16445 GO:2000631 biolink:BiologicalProcess regulation of pre-miRNA processing Any process that modulates the frequency, rate or extent of pre-microRNA processing. go-plus.json regulation of pre-microRNA processing http://purl.obolibrary.org/obo/GO_2000631 CHEBI:16446 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16446 GO:0002519 biolink:BiologicalProcess natural killer cell tolerance induction Tolerance induction of natural killer cells. go-plus.json NK cell tolerance induction http://purl.obolibrary.org/obo/GO_0002519 GO:0051481 biolink:BiologicalProcess negative regulation of cytosolic calcium ion concentration Any process that decreases the concentration of calcium ions in the cytosol. go-plus.json cytoplasmic calcium ion concentration reduction|cytosolic calcium ion concentration reduction|reduction of calcium ion concentration in cytoplasm|reduction of cytoplasmic calcium ion concentration|reduction of calcium ion concentration in cytosol|reduction of cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_0051481 CHEBI:16443 biolink:ChemicalSubstance D-tagatose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16443 GO:0051482 biolink:BiologicalProcess positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol. go-plus.json elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger http://purl.obolibrary.org/obo/GO_0051482 CHEBI:16444 biolink:ChemicalSubstance 2-acetyllactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16444 CHEBI:16441 biolink:ChemicalSubstance linamarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16441 chebi_ph7_3 GO:0051480 biolink:BiologicalProcess regulation of cytosolic calcium ion concentration Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings. go-plus.json cytoplasmic calcium ion concentration regulation|regulation of calcium ion concentration in cytosol|cytosolic calcium ion concentration regulation|regulation of cytoplasmic calcium ion concentration|calcium ion homeostasis in cytoplasm|regulation of cytosolic calcium ion concentration|calcium ion homeostasis in cytosol|cytoplasmic calcium ion homeostasis|regulation of calcium ion concentration in cytoplasm http://purl.obolibrary.org/obo/GO_0051480 GO:0002515 biolink:BiologicalProcess B cell anergy Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction. go-plus.json B-lymphocyte anergy|B-cell anergy|B lymphocyte anergy http://purl.obolibrary.org/obo/GO_0002515 GO:0051485 biolink:BiologicalProcess terpenoid biosynthetic process, mevalonate-dependent The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates. go-plus.json terpenoid synthesis, mevalonate-dependent|terpene biosynthesis, mevalonate-dependent|terpene biosynthetic process, mevalonate-dependent|terpenoid formation, mevalonate-dependent|terpenoid anabolism, mevalonate-dependent http://purl.obolibrary.org/obo/GO_0051485 CHEBI:90384 biolink:ChemicalSubstance alpha-Neu5Gc-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90384 chebi_ph7_3 GO:0002516 biolink:BiologicalProcess B cell deletion The apoptotic death of B cells which is part of B cell tolerance induction. go-plus.json B-lymphocyte deletion|B-cell deletion|B lymphocyte deletion http://purl.obolibrary.org/obo/GO_0002516 GO:0051486 biolink:BiologicalProcess isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates. go-plus.json isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis|isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism|isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process|isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis|isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation http://purl.obolibrary.org/obo/GO_0051486 CHEBI:16440 biolink:ChemicalSubstance N-methyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16440 CHEBI:170010 biolink:ChemicalSubstance EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_170010 GO:0051483 biolink:BiologicalProcess terpenoid biosynthetic process, mevalonate-independent The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate. go-plus.json terpenoid anabolism, mevalonate-independent|terpenoid synthesis, mevalonate-independent|terpene biosynthesis, mevalonate-independent|terpene biosynthetic process, mevalonate-independent|terpenoid formation, mevalonate-independent|mevalonate-independent terpene biosynthetic process|mevalonate-independent terpene biosynthesis|mevalonate-independent terpenoid biosynthesis|mevalonate-independent terpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0051483 GO:0002517 biolink:BiologicalProcess T cell tolerance induction A process involving any mechanism for tolerance induction in T cells. go-plus.json T-cell tolerance induction|T-lymphocyte tolerance induction|T lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002517 GO:0002518 biolink:BiologicalProcess lymphocyte chemotaxis across high endothelial venule The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002518 GO:0051484 biolink:BiologicalProcess isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. MetaCyc:NONMEVIPP-PWY go-plus.json isopentenyl diphosphate synthesis, mevalonate-independent pathway, during terpenoid synthesis|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid formation|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway involved in terpenoid biosynthetic process|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid biosynthesis|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, during terpenoid biosynthetic process|isopentenyl diphosphate anabolism, mevalonate-independent pathway, during terpenoid anabolism http://purl.obolibrary.org/obo/GO_0051484 UBERON:0023879 biolink:AnatomicalEntity neural system A set of neural structures that subserve a specific function, e.g., visual system go-plus.json neural system http://purl.obolibrary.org/obo/UBERON_0023879 CHEBI:16480 biolink:ChemicalSubstance nitric oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16480 chebi_ph7_3 GO:0051498 biolink:MolecularActivity syn-copalyl diphosphate synthase activity Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate. MetaCyc:RXN-8528|EC:5.5.1.14|RHEA:25524 go-plus.json diterpene cyclase activity http://purl.obolibrary.org/obo/GO_0051498 NCBITaxon:4513 biolink:OrganismalEntity Hordeum vulgare go-plus.json barley http://purl.obolibrary.org/obo/NCBITaxon_4513 GO:0051499 biolink:MolecularActivity D-aminoacyl-tRNA deacylase activity Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA. MetaCyc:RXN-15041|EC:3.1.1.96|RHEA:13953 go-plus.json http://purl.obolibrary.org/obo/GO_0051499 NCBITaxon:4512 biolink:OrganismalEntity Hordeum go-plus.json barleys http://purl.obolibrary.org/obo/NCBITaxon_4512 GO:2000643 biolink:BiologicalProcess positive regulation of early endosome to late endosome transport Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000643 GO:2000644 biolink:BiologicalProcess regulation of receptor catabolic process Any process that modulates the frequency, rate or extent of receptor catabolic process. go-plus.json regulation of receptor catabolism|regulation of receptor degradation|regulation of receptor breakdown http://purl.obolibrary.org/obo/GO_2000644 GO:2000645 biolink:BiologicalProcess negative regulation of receptor catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process. go-plus.json negative regulation of receptor degradation|negative regulation of receptor breakdown|negative regulation of receptor catabolism http://purl.obolibrary.org/obo/GO_2000645 GO:2000646 biolink:BiologicalProcess positive regulation of receptor catabolic process Any process that activates or increases the frequency, rate or extent of receptor catabolic process. go-plus.json positive regulation of receptor degradation|positive regulation of receptor catabolism|positive regulation of receptor breakdown http://purl.obolibrary.org/obo/GO_2000646 GO:1905670 biolink:BiologicalProcess TORC2 complex disassembly The disaggregation of a TORC2 complex into its constituent components. go-plus.json TORC 2 complex disassembly|TORC2 disassembly|rapamycin and nutrient-insensitive TOR complex disassembly|mTORC2 disassembly|TOR complex 2 disassembly http://purl.obolibrary.org/obo/GO_1905670 GO:2000647 biolink:BiologicalProcess negative regulation of stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000647 GO:1905671 biolink:BiologicalProcess regulation of lysosome organization Any process that modulates the frequency, rate or extent of lysosome organization. go-plus.json regulation of lysosome organization and biogenesis|regulation of lysosome organisation http://purl.obolibrary.org/obo/GO_1905671 GO:1905672 biolink:BiologicalProcess negative regulation of lysosome organization Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization. go-plus.json down regulation of lysosome organization|downregulation of lysosome organization and biogenesis|downregulation of lysosome organization|down regulation of lysosome organization and biogenesis|negative regulation of lysosome organisation|down-regulation of lysosome organisation|inhibition of lysosome organisation|down-regulation of lysosome organization|inhibition of lysosome organization and biogenesis|inhibition of lysosome organization|negative regulation of lysosome organization and biogenesis|down-regulation of lysosome organization and biogenesis|down regulation of lysosome organisation|downregulation of lysosome organisation http://purl.obolibrary.org/obo/GO_1905672 GO:2000648 biolink:BiologicalProcess positive regulation of stem cell proliferation Any process that activates or increases the frequency, rate or extent of stem cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2000648 GO:1905673 biolink:BiologicalProcess positive regulation of lysosome organization Any process that activates or increases the frequency, rate or extent of lysosome organization. go-plus.json up regulation of lysosome organization and biogenesis|up regulation of lysosome organisation|activation of lysosome organisation|positive regulation of lysosome organisation|up regulation of lysosome organization|activation of lysosome organization|upregulation of lysosome organization and biogenesis|up-regulation of lysosome organisation|up-regulation of lysosome organization and biogenesis|up-regulation of lysosome organization|upregulation of lysosome organisation|activation of lysosome organization and biogenesis|positive regulation of lysosome organization and biogenesis|upregulation of lysosome organization http://purl.obolibrary.org/obo/GO_1905673 GO:2000649 biolink:BiologicalProcess regulation of sodium ion transmembrane transporter activity Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity. go-plus.json regulation of sodium transporter activity http://purl.obolibrary.org/obo/GO_2000649 GO:1905674 biolink:BiologicalProcess regulation of adaptive immune memory response Any process that modulates the frequency, rate or extent of adaptive immune memory response. go-plus.json http://purl.obolibrary.org/obo/GO_1905674 GO:1905664 biolink:BiologicalProcess regulation of calcium ion import across plasma membrane Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905664 GO:1905665 biolink:BiologicalProcess positive regulation of calcium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane. go-plus.json upregulation of calcium ion import across plasma membrane|up regulation of calcium ion import across plasma membrane|activation of calcium ion import across plasma membrane|up-regulation of calcium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1905665 GO:1905666 biolink:BiologicalProcess regulation of protein localization to endosome Any process that modulates the frequency, rate or extent of protein localization to endosome. go-plus.json regulation of protein localisation in endosome|regulation of protein localization in endosome http://purl.obolibrary.org/obo/GO_1905666 GO:1905667 biolink:BiologicalProcess negative regulation of protein localization to endosome Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome. go-plus.json downregulation of protein localization to endosome|down-regulation of protein localization in endosome|negative regulation of protein localization in endosome|downregulation of protein localisation in endosome|down regulation of protein localization to endosome|inhibition of protein localization to endosome|down regulation of protein localisation in endosome|inhibition of protein localisation in endosome|downregulation of protein localization in endosome|down regulation of protein localization in endosome|inhibition of protein localization in endosome|down-regulation of protein localization to endosome|negative regulation of protein localisation in endosome|down-regulation of protein localisation in endosome http://purl.obolibrary.org/obo/GO_1905667 GO:1905668 biolink:BiologicalProcess positive regulation of protein localization to endosome Any process that activates or increases the frequency, rate or extent of protein localization to endosome. go-plus.json up regulation of protein localization to endosome|positive regulation of protein localisation in endosome|up regulation of protein localisation in endosome|positive regulation of protein localization in endosome|upregulation of protein localization to endosome|up regulation of protein localization in endosome|upregulation of protein localisation in endosome|activation of protein localization to endosome|up-regulation of protein localization to endosome|upregulation of protein localization in endosome|up-regulation of protein localisation in endosome|activation of protein localisation in endosome|activation of protein localization in endosome|up-regulation of protein localization in endosome http://purl.obolibrary.org/obo/GO_1905668 GO:1905669 biolink:BiologicalProcess TORC1 complex assembly The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex. go-plus.json nutrient sensitive complex assembly|TORC 1 complex assembly|dTORC1 formation|TORC1 formation|rapamycin and nutrient-sensitive TOR complex formation|mTORC1 assembly|mTORC1 formation|TOR complex 1 assembly|dTORC1 assembly|TOR complex 1 formation|TORC1 complex formation|dTOR/dRaptor complex formation|rapamycin and nutrient-sensitive TOR complex assembly|TORC1 assembly|TORC 1 complex formation|nutrient sensitive complex formation|dTOR/dRaptor complex assembly http://purl.obolibrary.org/obo/GO_1905669 GO:2000640 biolink:BiologicalProcess positive regulation of SREBP signaling pathway Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway. go-plus.json positive regulation of SREBP-mediated signalling pathway|positive regulation of SREBP-mediated signaling pathway http://purl.obolibrary.org/obo/GO_2000640 CHEBI:16478 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_16478 chebi_ph7_3 GO:2000641 biolink:BiologicalProcess regulation of early endosome to late endosome transport Any process that modulates the frequency, rate or extent of early endosome to late endosome transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000641 GO:2000642 biolink:BiologicalProcess negative regulation of early endosome to late endosome transport Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport. go-plus.json http://purl.obolibrary.org/obo/GO_2000642 CHEBI:16479 biolink:ChemicalSubstance streptomycin 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16479 CHEBI:41402 biolink:ChemicalSubstance carboxymethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_41402 GO:0051492 biolink:BiologicalProcess regulation of stress fiber assembly Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. go-plus.json regulation of stress fibre biosynthesis|regulation of stress fibre formation http://purl.obolibrary.org/obo/GO_0051492 GO:0051493 biolink:BiologicalProcess regulation of cytoskeleton organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. go-plus.json regulation of cytoskeleton organisation|regulation of cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0051493 GO:0051490 biolink:BiologicalProcess negative regulation of filopodium assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. go-plus.json down regulation of filopodium formation|inhibition of filopodium formation|negative regulation of filopodium formation|negative regulation of filopodia biosynthesis|down-regulation of filopodium formation|negative regulation of filopodia formation|downregulation of filopodium formation http://purl.obolibrary.org/obo/GO_0051490 CHEBI:16474 biolink:ChemicalSubstance NADPH go-plus.json http://purl.obolibrary.org/obo/CHEBI_16474 GO:0051491 biolink:BiologicalProcess positive regulation of filopodium assembly Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. go-plus.json upregulation of filopodium formation|stimulation of filopodium formation|up-regulation of filopodium formation|positive regulation of filopodium formation|activation of filopodium formation|positive regulation of filopodia biosynthesis|positive regulation of filopodia formation|up regulation of filopodium formation http://purl.obolibrary.org/obo/GO_0051491 CHEBI:16475 biolink:ChemicalSubstance 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16475 GO:0051496 biolink:BiologicalProcess positive regulation of stress fiber assembly Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. go-plus.json positive regulation of stress fibre biosynthesis|up regulation of stress fiber formation|upregulation of stress fiber formation|stimulation of stress fiber formation|activation of stress fiber formation|up-regulation of stress fiber formation|positive regulation of stress fibre formation http://purl.obolibrary.org/obo/GO_0051496 CHEBI:16472 biolink:ChemicalSubstance pentan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_16472 chebi_ph7_3 GO:0051497 biolink:BiologicalProcess negative regulation of stress fiber assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. go-plus.json negative regulation of stress fibre biosynthesis|downregulation of stress fiber formation|inhibition of stress fiber formation|down regulation of stress fiber formation|negative regulation of stress fibre formation|down-regulation of stress fiber formation http://purl.obolibrary.org/obo/GO_0051497 CHEBI:16473 biolink:ChemicalSubstance cortisol 21-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16473 GO:0051494 biolink:BiologicalProcess negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. go-plus.json down regulation of cytoskeleton organization|downregulation of cytoskeleton organization|negative regulation of cytoskeleton organisation|down-regulation of cytoskeleton organization|inhibition of cytoskeleton organization|negative regulation of cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0051494 UBERON:0008202 biolink:AnatomicalEntity bone of hip region go-plus.json http://purl.obolibrary.org/obo/UBERON_0008202 CHEBI:16470 biolink:ChemicalSubstance glyceollin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16470 chebi_ph7_3 GO:0051495 biolink:BiologicalProcess positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. go-plus.json positive regulation of cytoskeleton organization and biogenesis|positive regulation of cytoskeleton organisation|up regulation of cytoskeleton organization|activation of cytoskeleton organization|stimulation of cytoskeleton organization|up-regulation of cytoskeleton organization|upregulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0051495 UBERON:0008203 biolink:AnatomicalEntity pelvic cavity The part of the ventral body cavity that is within the pelvis. go-plus.json cavitas pelvis|space of pelvic compartment http://purl.obolibrary.org/obo/UBERON_0008203 CHEBI:16471 biolink:ChemicalSubstance (dimethylsulfonio)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16471 chebi_ph7_3 GO:0099401 biolink:CellularComponent caveola bulb The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins. go-plus.json caveola crater http://purl.obolibrary.org/obo/GO_0099401 NCBITaxon:4527 biolink:OrganismalEntity Oryza go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4527 GO:0099402 biolink:BiologicalProcess plant organ development Development of a plant organ, a multi-tissue plant structure that forms a functional unit. go-plus.json development of a plant organ http://purl.obolibrary.org/obo/GO_0099402 GO:0099400 biolink:CellularComponent caveola neck A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it. go-plus.json http://purl.obolibrary.org/obo/GO_0099400 GO:2000654 biolink:BiologicalProcess regulation of cellular response to testosterone stimulus Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_2000654 GO:2000655 biolink:BiologicalProcess negative regulation of cellular response to testosterone stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_2000655 GO:2000656 biolink:BiologicalProcess regulation of apolipoprotein binding Any process that modulates the frequency, rate or extent of apolipoprotein binding. go-plus.json http://purl.obolibrary.org/obo/GO_2000656 GO:1905680 biolink:BiologicalProcess regulation of innate immunity memory response Any process that modulates the frequency, rate or extent of innate immunity memory response. go-plus.json http://purl.obolibrary.org/obo/GO_1905680 GO:1905681 biolink:BiologicalProcess negative regulation of innate immunity memory response Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response. go-plus.json down regulation of innate immunity memory response|downregulation of innate immunity memory response|down-regulation of innate immunity memory response|inhibition of innate immunity memory response http://purl.obolibrary.org/obo/GO_1905681 GO:2000657 biolink:BiologicalProcess negative regulation of apolipoprotein binding Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding. go-plus.json http://purl.obolibrary.org/obo/GO_2000657 GO:1905682 biolink:BiologicalProcess positive regulation of innate immunity memory response Any process that activates or increases the frequency, rate or extent of innate immunity memory response. go-plus.json up regulation of innate immunity memory response|activation of innate immunity memory response|up-regulation of innate immunity memory response|upregulation of innate immunity memory response http://purl.obolibrary.org/obo/GO_1905682 GO:2000658 biolink:BiologicalProcess positive regulation of apolipoprotein binding Any process that activates or increases the frequency, rate or extent of apolipoprotein binding. go-plus.json http://purl.obolibrary.org/obo/GO_2000658 GO:2000659 biolink:BiologicalProcess regulation of interleukin-1-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway. go-plus.json regulation of interleukin-1 alpha-mediated signaling pathway|regulation of interleukin-1-mediated signalling pathway|regulation of interleukin-1 beta-mediated signaling pathway|regulation of IL-1-mediated signaling pathway|regulation of IL-1 beta-mediated signaling pathway|regulation of IL-1 alpha-mediated signaling pathway http://purl.obolibrary.org/obo/GO_2000659 GO:1905683 biolink:BiologicalProcess peroxisome disassembly The disaggregation of a peroxisome into its constituent components. go-plus.json peroxisomal disassembly http://purl.obolibrary.org/obo/GO_1905683 GO:1905684 biolink:BiologicalProcess regulation of plasma membrane repair Any process that modulates the frequency, rate or extent of plasma membrane repair. go-plus.json http://purl.obolibrary.org/obo/GO_1905684 GO:1905685 biolink:BiologicalProcess negative regulation of plasma membrane repair Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair. go-plus.json downregulation of plasma membrane repair|down regulation of plasma membrane repair|inhibition of plasma membrane repair|down-regulation of plasma membrane repair http://purl.obolibrary.org/obo/GO_1905685 GO:1905675 biolink:BiologicalProcess negative regulation of adaptive immune memory response Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response. go-plus.json down regulation of adaptive immune memory response|downregulation of adaptive immune memory response|down-regulation of adaptive immune memory response|inhibition of adaptive immune memory response http://purl.obolibrary.org/obo/GO_1905675 GO:1905676 biolink:BiologicalProcess positive regulation of adaptive immune memory response Any process that activates or increases the frequency, rate or extent of adaptive immune memory response. go-plus.json up-regulation of adaptive immune memory response|upregulation of adaptive immune memory response|up regulation of adaptive immune memory response|activation of adaptive immune memory response http://purl.obolibrary.org/obo/GO_1905676 GO:1905677 biolink:BiologicalProcess regulation of adaptive immune effector response Any process that modulates the frequency, rate or extent of adaptive immune effector response. go-plus.json http://purl.obolibrary.org/obo/GO_1905677 GO:1905678 biolink:BiologicalProcess negative regulation of adaptive immune effector response Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response. go-plus.json down regulation of adaptive immune effector response|downregulation of adaptive immune effector response|down-regulation of adaptive immune effector response|inhibition of adaptive immune effector response http://purl.obolibrary.org/obo/GO_1905678 GO:1905679 biolink:BiologicalProcess positive regulation of adaptive immune effector response Any process that activates or increases the frequency, rate or extent of adaptive immune effector response. go-plus.json up regulation of adaptive immune effector response|activation of adaptive immune effector response|up-regulation of adaptive immune effector response|upregulation of adaptive immune effector response http://purl.obolibrary.org/obo/GO_1905679 GO:2000650 biolink:BiologicalProcess negative regulation of sodium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity. go-plus.json negative regulation of sodium transporter activity http://purl.obolibrary.org/obo/GO_2000650 CHEBI:16469 biolink:ChemicalSubstance 17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16469 chebi_ph7_3 GO:2000651 biolink:BiologicalProcess positive regulation of sodium ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity. go-plus.json positive regulation of sodium transporter activity http://purl.obolibrary.org/obo/GO_2000651 GO:2000652 biolink:BiologicalProcess regulation of secondary cell wall biogenesis Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis. go-plus.json regulation of secondary cell wall synthesis|regulation of plant-type secondary cell wall biogenesis|regulation of secondary cell wall formation|regulation of cellulose and pectin-containing secondary cell wall biogenesis|regulation of secondary cell wall biosynthetic process|regulation of secondary cell wall anabolism http://purl.obolibrary.org/obo/GO_2000652 CHEBI:16467 biolink:ChemicalSubstance L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16467 GO:2000653 biolink:BiologicalProcess regulation of genetic imprinting Any process that modulates the frequency, rate or extent of genetic imprinting. go-plus.json regulation of DNA imprinting http://purl.obolibrary.org/obo/GO_2000653 CHEBI:16468 biolink:ChemicalSubstance maleylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16468 chebi_ph7_3 NCBITaxon:4530 biolink:OrganismalEntity Oryza sativa go-plus.json rice|red rice http://purl.obolibrary.org/obo/NCBITaxon_4530 CHEBI:16466 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_16466 chebi_ph7_3 CHEBI:16463 biolink:ChemicalSubstance N-methylethanolamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16463 CHEBI:16464 biolink:ChemicalSubstance salicyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16464 chebi_ph7_3 CHEBI:16461 biolink:ChemicalSubstance tauropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16461 GO:0099403 biolink:BiologicalProcess maintenance of mitotic sister chromatid cohesion, telomeric The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. go-plus.json maintenance of mitotic sister chromatin cohesion at telomere|maintenance of telomeric mitotic sister chromatin cohesion|maintenance of sister chromatin cohesion at telomere at mitosis http://purl.obolibrary.org/obo/GO_0099403 GO:0099404 biolink:BiologicalProcess mitotic sister chromatid cohesion, telomeric The cell cycle process in which telomeres of sister chromatids are joined during mitosis. go-plus.json telomeric mitotic sister chromatin cohesion|sister chromatid cohesion at telomere at mitosis|mitotic sister chromatid cohesion at telomere http://purl.obolibrary.org/obo/GO_0099404 CHEBI:16460 biolink:ChemicalSubstance polyprenol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16460 NCBITaxon:4577 biolink:OrganismalEntity Zea mays go-plus.json maize|Zea mays var. japonica http://purl.obolibrary.org/obo/NCBITaxon_4577 NCBITaxon:4575 biolink:OrganismalEntity Zea go-plus.json Euchlaena http://purl.obolibrary.org/obo/NCBITaxon_4575 GO:1905690 biolink:BiologicalProcess nucleus disassembly The disaggregation of a nucleus into its constituent components. go-plus.json cell nucleus disassembly http://purl.obolibrary.org/obo/GO_1905690 GO:1905691 biolink:BiologicalProcess lipid droplet disassembly The disaggregation of a lipid particle into its constituent components. go-plus.json lipid droplet reserve breakdown|adiposome disassembly|lipid particle disassembly|lipid body disassembly http://purl.obolibrary.org/obo/GO_1905691 GO:1905692 biolink:BiologicalProcess endoplasmic reticulum disassembly The disaggregation of an endoplasmic reticulum into its constituent components. go-plus.json ER disassembly http://purl.obolibrary.org/obo/GO_1905692 GO:1905693 biolink:BiologicalProcess regulation of phosphatidic acid biosynthetic process Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process. go-plus.json regulation of phosphatidic acid synthesis|regulation of phosphatidic acid formation|regulation of phosphatidic acid biosynthesis|regulation of phosphatidic acid anabolism http://purl.obolibrary.org/obo/GO_1905693 GO:1905694 biolink:BiologicalProcess negative regulation of phosphatidic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process. go-plus.json down regulation of phosphatidic acid formation|downregulation of phosphatidic acid biosynthesis|downregulation of phosphatidic acid biosynthetic process|downregulation of phosphatidic acid synthesis|downregulation of phosphatidic acid formation|down regulation of phosphatidic acid biosynthesis|down regulation of phosphatidic acid biosynthetic process|down-regulation of phosphatidic acid anabolism|negative regulation of phosphatidic acid anabolism|inhibition of phosphatidic acid biosynthetic process|inhibition of phosphatidic acid biosynthesis|down-regulation of phosphatidic acid synthesis|negative regulation of phosphatidic acid synthesis|down-regulation of phosphatidic acid formation|inhibition of phosphatidic acid anabolism|negative regulation of phosphatidic acid formation|inhibition of phosphatidic acid synthesis|inhibition of phosphatidic acid formation|negative regulation of phosphatidic acid biosynthesis|down-regulation of phosphatidic acid biosynthetic process|down-regulation of phosphatidic acid biosynthesis|down regulation of phosphatidic acid anabolism|down regulation of phosphatidic acid synthesis|downregulation of phosphatidic acid anabolism http://purl.obolibrary.org/obo/GO_1905694 GO:1905695 biolink:BiologicalProcess positive regulation of phosphatidic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process. go-plus.json upregulation of phosphatidic acid formation|up regulation of phosphatidic acid biosynthesis|up regulation of phosphatidic acid biosynthetic process|up regulation of phosphatidic acid anabolism|activation of phosphatidic acid anabolism|positive regulation of phosphatidic acid anabolism|up regulation of phosphatidic acid synthesis|activation of phosphatidic acid synthesis|positive regulation of phosphatidic acid synthesis|up regulation of phosphatidic acid formation|upregulation of phosphatidic acid biosynthesis|activation of phosphatidic acid formation|upregulation of phosphatidic acid biosynthetic process|positive regulation of phosphatidic acid formation|up-regulation of phosphatidic acid anabolism|activation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid synthesis|activation of phosphatidic acid biosynthetic process|up-regulation of phosphatidic acid biosynthetic process|up-regulation of phosphatidic acid formation|upregulation of phosphatidic acid anabolism|upregulation of phosphatidic acid synthesis|positive regulation of phosphatidic acid biosynthesis http://purl.obolibrary.org/obo/GO_1905695 GO:1905696 biolink:BiologicalProcess regulation of polysome binding Any process that modulates the frequency, rate or extent of polysome binding. go-plus.json regulation of polyribosome binding http://purl.obolibrary.org/obo/GO_1905696 GO:1905686 biolink:BiologicalProcess positive regulation of plasma membrane repair Any process that activates or increases the frequency, rate or extent of plasma membrane repair. go-plus.json up regulation of plasma membrane repair|upregulation of plasma membrane repair|up-regulation of plasma membrane repair|activation of plasma membrane repair http://purl.obolibrary.org/obo/GO_1905686 GO:1905687 biolink:BiologicalProcess regulation of diacylglycerol kinase activity Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity. go-plus.json regulation of sn-1,2-diacylglycerol kinase activity|regulation of 1,2-diacylglycerol kinase (phosphorylating)|regulation of CTP:diacylglycerol kinase activity|regulation of ATP:diacylglycerol phosphotransferase activity|regulation of 1,2-diacylglycerol kinase activity|regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|regulation of arachidonoyl-specific diacylglycerol kinase activity|regulation of DG kinase activity|regulation of diglyceride kinase activity|regulation of diacylglycerol:ATP kinase activity|regulation of DGK activity http://purl.obolibrary.org/obo/GO_1905687 CHEBI:16419 biolink:ChemicalSubstance limonoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16419 GO:1905688 biolink:BiologicalProcess negative regulation of diacylglycerol kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity. go-plus.json inhibition of DGK activity|negative regulation of diglyceride kinase activity|down-regulation of diglyceride kinase activity|down-regulation of ATP:diacylglycerol phosphotransferase activity|negative regulation of ATP:diacylglycerol phosphotransferase activity|down regulation of sn-1,2-diacylglycerol kinase activity|down regulation of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of CTP:diacylglycerol kinase activity|downregulation of diacylglycerol kinase activity|down-regulation of 1,2-diacylglycerol kinase activity|negative regulation of 1,2-diacylglycerol kinase activity|inhibition of diacylglycerol:ATP kinase activity|negative regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|downregulation of sn-1,2-diacylglycerol kinase activity|down-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|inhibition of diglyceride kinase activity|downregulation of 1,2-diacylglycerol kinase (phosphorylating)|negative regulation of arachidonoyl-specific diacylglycerol kinase activity|down-regulation of arachidonoyl-specific diacylglycerol kinase activity|down regulation of CTP:diacylglycerol kinase activity|down regulation of diacylglycerol kinase activity|inhibition of diacylglycerol kinase activity|negative regulation of DG kinase activity|downregulation of ATP:diacylglycerol phosphotransferase activity|down-regulation of DG kinase activity|downregulation of 1,2-diacylglycerol kinase activity|inhibition of CTP:diacylglycerol kinase activity|down-regulation of sn-1,2-diacylglycerol kinase activity|negative regulation of sn-1,2-diacylglycerol kinase activity|down regulation of ATP:diacylglycerol phosphotransferase activity|downregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down-regulation of 1,2-diacylglycerol kinase (phosphorylating)|negative regulation of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of arachidonoyl-specific diacylglycerol kinase activity|down-regulation of diacylglycerol:ATP kinase activity|down regulation of 1,2-diacylglycerol kinase activity|negative regulation of diacylglycerol:ATP kinase activity|negative regulation of DGK activity|down-regulation of DGK activity|down regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|inhibition of 1,2-diacylglycerol kinase activity|downregulation of DG kinase activity|down regulation of diglyceride kinase activity|down regulation of arachidonoyl-specific diacylglycerol kinase activity|inhibition of arachidonoyl-specific diacylglycerol kinase activity|inhibition of sn-1,2-diacylglycerol kinase activity|inhibition of ATP:diacylglycerol phosphotransferase activity|inhibition of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of diglyceride kinase activity|down regulation of DG kinase activity|inhibition of DG kinase activity|down-regulation of CTP:diacylglycerol kinase activity|negative regulation of CTP:diacylglycerol kinase activity|inhibition of ATP:1,2-diacylglycerol 3-phosphotransferase activity|downregulation of diacylglycerol:ATP kinase activity|down-regulation of diacylglycerol kinase activity|downregulation of DGK activity|down regulation of diacylglycerol:ATP kinase activity|down regulation of DGK activity http://purl.obolibrary.org/obo/GO_1905688 GO:1905689 biolink:BiologicalProcess positive regulation of diacylglycerol kinase activity Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity. go-plus.json activation of arachidonoyl-specific diacylglycerol kinase activity|up regulation of diacylglycerol kinase activity|up regulation of CTP:diacylglycerol kinase activity|activation of ATP:diacylglycerol phosphotransferase activity|upregulation of diacylglycerol:ATP kinase activity|upregulation of DGK activity|up-regulation of DG kinase activity|activation of DG kinase activity|activation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of ATP:diacylglycerol phosphotransferase activity|up-regulation of diglyceride kinase activity|up regulation of sn-1,2-diacylglycerol kinase activity|up regulation of ATP:diacylglycerol phosphotransferase activity|positive regulation of 1,2-diacylglycerol kinase activity|up regulation of 1,2-diacylglycerol kinase (phosphorylating)|positive regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of sn-1,2-diacylglycerol kinase activity|activation of sn-1,2-diacylglycerol kinase activity|positive regulation of arachidonoyl-specific diacylglycerol kinase activity|upregulation of diacylglycerol kinase activity|up regulation of 1,2-diacylglycerol kinase activity|upregulation of CTP:diacylglycerol kinase activity|up-regulation of DGK activity|up-regulation of diacylglycerol:ATP kinase activity|activation of 1,2-diacylglycerol kinase (phosphorylating)|positive regulation of 1,2-diacylglycerol kinase (phosphorylating)|up regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up regulation of arachidonoyl-specific diacylglycerol kinase activity|activation of DGK activity|positive regulation of DG kinase activity|upregulation of diglyceride kinase activity|up regulation of DG kinase activity|activation of diacylglycerol:ATP kinase activity|upregulation of ATP:diacylglycerol phosphotransferase activity|up-regulation of CTP:diacylglycerol kinase activity|up-regulation of diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase activity|activation of diacylglycerol kinase activity|up-regulation of sn-1,2-diacylglycerol kinase activity|positive regulation of diacylglycerol:ATP kinase activity|up-regulation of 1,2-diacylglycerol kinase (phosphorylating)|upregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|upregulation of arachidonoyl-specific diacylglycerol kinase activity|positive regulation of DGK activity|up regulation of DGK activity|up regulation of diacylglycerol:ATP kinase activity|activation of CTP:diacylglycerol kinase activity|upregulation of DG kinase activity|up regulation of diglyceride kinase activity|up-regulation of ATP:diacylglycerol phosphotransferase activity|activation of diglyceride kinase activity|positive regulation of diglyceride kinase activity|up-regulation of 1,2-diacylglycerol kinase activity|upregulation of sn-1,2-diacylglycerol kinase activity|activation of 1,2-diacylglycerol kinase activity|positive regulation of CTP:diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase (phosphorylating)|up-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up-regulation of arachidonoyl-specific diacylglycerol kinase activity http://purl.obolibrary.org/obo/GO_1905689 CHEBI:16414 biolink:ChemicalSubstance L-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16414 CHEBI:16415 biolink:ChemicalSubstance protopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16415 chebi_ph7_3 CHEBI:16412 biolink:ChemicalSubstance lipopolysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16412 CHEBI:16413 biolink:ChemicalSubstance but-2-yne-1,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16413 chebi_ph7_3 CHEBI:16410 biolink:ChemicalSubstance pyridoxamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16410 CHEBI:16411 biolink:ChemicalSubstance indole-3-acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16411 UBERON:0008266 biolink:AnatomicalEntity periodontal ligament The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]. go-plus.json peridontal fiber|alveolar periosteum|periodontal fiber|peridontal ligament|periodontium|alveolodental ligament|peridontal membrane|alveolodental membrane|odontoperiosteum|peridontium|peridontal ligament fibre|fibra periodontalis|desmodontium|paradentium|peridontal fibre|peridontal ligament fiber|PDL|periodontal fibre|peridental membrane http://purl.obolibrary.org/obo/UBERON_0008266 CHEBI:16409 biolink:ChemicalSubstance 5-pyridoxic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16409 GO:1905697 biolink:BiologicalProcess negative regulation of polysome binding Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding. go-plus.json down-regulation of polysome binding|downregulation of polyribosome binding|down regulation of polyribosome binding|downregulation of polysome binding|inhibition of polyribosome binding|down regulation of polysome binding|inhibition of polysome binding|down-regulation of polyribosome binding|negative regulation of polyribosome binding http://purl.obolibrary.org/obo/GO_1905697 GO:1905698 biolink:BiologicalProcess positive regulation of polysome binding Any process that activates or increases the frequency, rate or extent of polysome binding. go-plus.json positive regulation of polyribosome binding|up regulation of polyribosome binding|up regulation of polysome binding|upregulation of polyribosome binding|upregulation of polysome binding|up-regulation of polyribosome binding|activation of polyribosome binding|up-regulation of polysome binding|activation of polysome binding http://purl.obolibrary.org/obo/GO_1905698 CHEBI:16408 biolink:ChemicalSubstance vomilenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16408 chebi_ph7_3 GO:1905699 biolink:BiologicalProcess regulation of xenobiotic detoxification by transmembrane export across the plasma membrane Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json regulation of drug transmembrane export|regulation of xenobiotic transmembrane export http://purl.obolibrary.org/obo/GO_1905699 CHEBI:16405 biolink:ChemicalSubstance beta-D-Xylp-(1->6)-beta-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_16405 chebi_ph7_3 CHEBI:16406 biolink:ChemicalSubstance 5'-acylphosphoadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16406 CHEBI:16404 biolink:ChemicalSubstance 3-oxoglycyrrhetinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16404 CHEBI:16400 biolink:ChemicalSubstance gossypetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16400 UBERON:0008255 biolink:AnatomicalEntity right clavicle A clavicle that is in the right side of a entire appendicular skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008255 UBERON:0008256 biolink:AnatomicalEntity left clavicle A clavicle that is in the left side of a entire appendicular skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008256 GO:2000607 biolink:BiologicalProcess negative regulation of cell proliferation involved in mesonephros development Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development. go-plus.json http://purl.obolibrary.org/obo/GO_2000607 GO:2000608 biolink:BiologicalProcess positive regulation of cell proliferation involved in mesonephros development Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development. go-plus.json http://purl.obolibrary.org/obo/GO_2000608 GO:2000609 biolink:BiologicalProcess regulation of thyroid hormone generation Any process that modulates the frequency, rate or extent of thyroid hormone generation. go-plus.json http://purl.obolibrary.org/obo/GO_2000609 NCBITaxon:4557 biolink:OrganismalEntity Sorghum go-plus.json Hemisorghum http://purl.obolibrary.org/obo/NCBITaxon_4557 NCBITaxon:4558 biolink:OrganismalEntity Sorghum bicolor go-plus.json broomcorn|Sorghum vulgare|Sorghum nervosum|Sorghum saccharatum|milo|Andropogon sorghum|Sorghum bicolor subsp. bicolor|sorghum http://purl.obolibrary.org/obo/NCBITaxon_4558 NCBITaxon:4555 biolink:OrganismalEntity Setaria italica go-plus.json Chaetochloa italica|Panicum italicum|Setaria viridis subsp. italica|foxtail millet http://purl.obolibrary.org/obo/NCBITaxon_4555 NCBITaxon:4554 biolink:OrganismalEntity Setaria go-plus.json Setaria http://purl.obolibrary.org/obo/NCBITaxon_4554 GO:2000600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000600 GO:2000601 biolink:BiologicalProcess positive regulation of Arp2/3 complex-mediated actin nucleation Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation. go-plus.json positive regulation of branched actin filament nucleation|positive regulation of actin filament branch nucleation http://purl.obolibrary.org/obo/GO_2000601 GO:2000602 biolink:BiologicalProcess obsolete regulation of interphase of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of interphase of mitotic cell cycle. go-plus.json regulation of interphase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2000602 GO:2000603 biolink:BiologicalProcess regulation of secondary growth Any process that modulates the frequency, rate or extent of secondary growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000603 GO:2000604 biolink:BiologicalProcess negative regulation of secondary growth Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000604 GO:2000605 biolink:BiologicalProcess positive regulation of secondary growth Any process that activates or increases the frequency, rate or extent of secondary growth. go-plus.json http://purl.obolibrary.org/obo/GO_2000605 GO:2000606 biolink:BiologicalProcess regulation of cell proliferation involved in mesonephros development Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development. go-plus.json http://purl.obolibrary.org/obo/GO_2000606 CHEBI:16439 biolink:ChemicalSubstance N-(carboxymethyl)-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16439 CHEBI:16436 biolink:ChemicalSubstance CDP-choline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16436 CHEBI:16437 biolink:ChemicalSubstance N-acetyl-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16437 CHEBI:16434 biolink:ChemicalSubstance N-hydroxy-4-acetylaminobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_16434 chebi_ph7_3 CHEBI:16435 biolink:ChemicalSubstance UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16435 CHEBI:16433 biolink:ChemicalSubstance trans-caffeic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16433 CHEBI:16430 biolink:ChemicalSubstance precorrin-4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_16430 CHEBI:16431 biolink:ChemicalSubstance limonene 1,2-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16431 chebi_ph7_3 UBERON:0008243 biolink:AnatomicalEntity upper back muscle A muscle of back that is part of a dorsal thoracic segment of trunk. go-plus.json http://purl.obolibrary.org/obo/UBERON_0008243 GO:2000618 biolink:BiologicalProcess regulation of histone H4-K16 acetylation Any process that modulates the frequency, rate or extent of histone H4-K16 acetylation. go-plus.json regulation of histone H4 acetylation at K16 http://purl.obolibrary.org/obo/GO_2000618 GO:2000619 biolink:BiologicalProcess negative regulation of histone H4-K16 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H4-K16 acetylation. go-plus.json negative regulation of histone H4 acetylation at K16 http://purl.obolibrary.org/obo/GO_2000619 NCBITaxon:4564 biolink:OrganismalEntity Triticum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_4564 NCBITaxon:4565 biolink:OrganismalEntity Triticum aestivum go-plus.json common wheat|Triticum vulgare|wheat|Canadian hard winter wheat|Triticum aestivum subsp. aestivum|bread wheat http://purl.obolibrary.org/obo/NCBITaxon_4565 GO:2000610 biolink:BiologicalProcess negative regulation of thyroid hormone generation Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation. go-plus.json http://purl.obolibrary.org/obo/GO_2000610 GO:2000611 biolink:BiologicalProcess positive regulation of thyroid hormone generation Any process that activates or increases the frequency, rate or extent of thyroid hormone generation. go-plus.json http://purl.obolibrary.org/obo/GO_2000611 GO:2000612 biolink:BiologicalProcess regulation of thyroid-stimulating hormone secretion Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion. go-plus.json regulation of thyroid stimulating hormone secretion|regulation of TSH secretion http://purl.obolibrary.org/obo/GO_2000612 GO:2000613 biolink:BiologicalProcess negative regulation of thyroid-stimulating hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion. go-plus.json negative regulation of thyroid stimulating hormone secretion|negative regulation of TSH secretion http://purl.obolibrary.org/obo/GO_2000613 GO:2000614 biolink:BiologicalProcess positive regulation of thyroid-stimulating hormone secretion Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion. go-plus.json positive regulation of thyroid stimulating hormone secretion|positive regulation of TSH secretion http://purl.obolibrary.org/obo/GO_2000614 GO:2000615 biolink:BiologicalProcess regulation of histone H3-K9 acetylation Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation. go-plus.json regulation of histone H3K9 acetylation|regulation of histone H3 acetylation at K9 http://purl.obolibrary.org/obo/GO_2000615 GO:2000616 biolink:BiologicalProcess negative regulation of histone H3-K9 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation. go-plus.json negative regulation of histone H3K9 acetylation|negative regulation of histone H3 acetylation at K9 http://purl.obolibrary.org/obo/GO_2000616 GO:2000617 biolink:BiologicalProcess positive regulation of histone H3-K9 acetylation Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation. go-plus.json positive regulation of histone H3K9 acetylation|positive regulation of histone H3 acetylation at K9 http://purl.obolibrary.org/obo/GO_2000617 CHEBI:16427 biolink:ChemicalSubstance mono(glucosyluronic acid)bilirubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16427 CHEBI:16428 biolink:ChemicalSubstance 4-coumaroylshikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16428 CHEBI:16425 biolink:ChemicalSubstance 16-epivellosimine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16425 chebi_ph7_3 CHEBI:16426 biolink:ChemicalSubstance 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16426 CHEBI:16423 biolink:ChemicalSubstance (9Z)-octadec-9-en-12-ynoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16423 CHEBI:16424 biolink:ChemicalSubstance phenylacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_16424 chebi_ph7_3 IAO:0000226 biolink:OntologyClass placeholder removed go-plus.json http://purl.obolibrary.org/obo/IAO_0000226 CHEBI:16421 biolink:ChemicalSubstance 1-deoxy-D-altro-heptulose 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16421 IAO:0000227 biolink:OntologyClass terms merged go-plus.json http://purl.obolibrary.org/obo/IAO_0000227 CHEBI:16422 biolink:ChemicalSubstance androst-4-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_16422 chebi_ph7_3 UBERON:0008231 biolink:AnatomicalEntity dorsal thoracic segment of trunk Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. go-plus.json dorsum of thorax|back of thorax|thoracic back|thoracic part of back|posterior part of thorax|upper back http://purl.obolibrary.org/obo/UBERON_0008231 IAO:0000224 biolink:OntologyClass core Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes. go-plus.json http://purl.obolibrary.org/obo/IAO_0000224 IAO:0000225 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/IAO_0000225 GO:0002467 biolink:BiologicalProcess germinal center formation The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. go-plus.json http://purl.obolibrary.org/obo/GO_0002467 GO:0002468 biolink:BiologicalProcess dendritic cell antigen processing and presentation The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002468 GO:0002469 biolink:BiologicalProcess myeloid dendritic cell antigen processing and presentation The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002469 GO:0002463 biolink:BiologicalProcess central tolerance induction to nonself antigen Tolerance induction to nonself antigens in the central lymphoid organs. go-plus.json http://purl.obolibrary.org/obo/GO_0002463 GO:0002464 biolink:BiologicalProcess peripheral tolerance induction to nonself antigen Tolerance induction to nonself antigens in the periphery. go-plus.json http://purl.obolibrary.org/obo/GO_0002464 GO:0002465 biolink:BiologicalProcess peripheral tolerance induction Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0002465 GO:0002466 biolink:BiologicalProcess peripheral tolerance induction to self antigen Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0002466 GO:0002460 biolink:BiologicalProcess adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0002460 GO:0002461 biolink:BiologicalProcess tolerance induction dependent upon immune response Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation. go-plus.json immune response-dependent tolerance induction http://purl.obolibrary.org/obo/GO_0002461 GO:0002462 biolink:BiologicalProcess tolerance induction to nonself antigen Tolerance induction in response to nonself antigens. go-plus.json http://purl.obolibrary.org/obo/GO_0002462 CHEBI:65352 biolink:ChemicalSubstance achromobactin free acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65352 CHEBI:90318 biolink:ChemicalSubstance EC 6.4.1.1 (pyruvate carboxylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_90318 CHEBI:90310 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-monoacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90310 chebi_ph7_3 GO:0051401 biolink:MolecularActivity CH domain binding Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins. go-plus.json calponin homology domain binding http://purl.obolibrary.org/obo/GO_0051401 GO:0002478 biolink:BiologicalProcess antigen processing and presentation of exogenous peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. go-plus.json exogenous peptide antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002478 GO:0051402 biolink:BiologicalProcess neuron apoptotic process Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. go-plus.json apoptosis of neurons|programmed cell death of neuronal cells by apoptosis|programmed cell death of neurons by apoptosis|programmed cell death, neurons|neuronal cell programmed cell death by apoptosis|neuronal cell apoptosis|programmed cell death, neuronal cells|apoptosis of neuronal cells|neuron apoptosis|neuron programmed cell death by apoptosis http://purl.obolibrary.org/obo/GO_0051402 GO:0002479 biolink:BiologicalProcess antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules. go-plus.json exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent|cross-presentation|TAP-dependent exogenous peptide antigen processing and presentation via MHC class I|TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I|cross presentation http://purl.obolibrary.org/obo/GO_0002479 GO:0051400 biolink:MolecularActivity BH domain binding Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains. go-plus.json Bcl-2 homology domain binding http://purl.obolibrary.org/obo/GO_0051400 goslim_chembl GO:0051405 biolink:MolecularActivity obsolete microbial collagenase activity OBSOLETE. Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds. go-plus.json collagenase MMP-1|matirx metalloproteinase-18|collagenase 1 activity|microbial collagenase activity|matrix metalloproteinase-8|kollaza|metallocollagenase activity|Clostridium histolyticum proteinase A|aspergillopeptidase C|clostridiopeptidase A activity|matrix metalloproteinase-1|metalloproteinase-1|azocollase activity|soycollagestin|clostridiopeptidase I|collagenase A activity|Achromobacter iophagus collagenase|collagen protease activity|collagen peptidase activity|nucleolysin|Clostridium histolyticum collagenase activity|collagenase I activity|clostridiopeptidase II http://purl.obolibrary.org/obo/GO_0051405 GO:0002474 biolink:BiologicalProcess antigen processing and presentation of peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. go-plus.json peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_0002474 GO:0002475 biolink:BiologicalProcess antigen processing and presentation via MHC class Ib The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. go-plus.json http://purl.obolibrary.org/obo/GO_0002475 GO:0051406 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051406 GO:0002476 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class Ib The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json endogenous peptide antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002476 GO:0051403 biolink:BiologicalProcess stress-activated MAPK cascade A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. go-plus.json SAPK cascade|p38 cascade|MAPK14 cascade|stress-activated MAPKKK signaling pathway|stress-activated MAPK signaling pathway|MAPK13 cascade|p38 MAPK signaling|MAPK12 cascade|MAPK11 cascade|stress-activated MAPK signalling pathway|stress-activated MAPKKK signalling pathway|stress-activated MAPKKK cascade|p38 MAPK signalling http://purl.obolibrary.org/obo/GO_0051403 GO:0051404 biolink:MolecularActivity obsolete clostripain activity OBSOLETE. Catalysis of the cleavage of Arg-Xaa bonds. go-plus.json alpha-clostridipain|clostripain activity|clostridiopeptidase B activity|Clostridium histolyticum proteinase B http://purl.obolibrary.org/obo/GO_0051404 GO:0002477 biolink:BiologicalProcess antigen processing and presentation of exogenous peptide antigen via MHC class Ib The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json exogenous peptide antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002477 GO:0051409 biolink:BiologicalProcess response to nitrosative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. go-plus.json http://purl.obolibrary.org/obo/GO_0051409 GO:0002470 biolink:BiologicalProcess plasmacytoid dendritic cell antigen processing and presentation The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002470 GO:0002471 biolink:BiologicalProcess monocyte antigen processing and presentation The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002471 GO:0002472 biolink:BiologicalProcess macrophage antigen processing and presentation The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0002472 GO:0051407 biolink:MolecularActivity glycerone phosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out). go-plus.json dihydroxyacetone-phosphate:inorganic phosphate antiporter activity http://purl.obolibrary.org/obo/GO_0051407 GO:0051408 biolink:MolecularActivity glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0051408 GO:0002473 biolink:BiologicalProcess non-professional antigen presenting cell antigen processing and presentation The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils. go-plus.json http://purl.obolibrary.org/obo/GO_0002473 CHEBI:80992 biolink:ChemicalSubstance thiohydroximic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80992 CHEBI:90307 biolink:ChemicalSubstance beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90307 chebi_ph7_3 GO:0051412 biolink:BiologicalProcess response to corticosterone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses. go-plus.json response to corticosterone stimulus http://purl.obolibrary.org/obo/GO_0051412 GO:0002445 biolink:BiologicalProcess type II hypersensitivity An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors. Wikipedia:Type_II_hypersensitivity go-plus.json http://purl.obolibrary.org/obo/GO_0002445 GO:0051413 biolink:BiologicalProcess response to cortisone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues. go-plus.json response to cortisone stimulus http://purl.obolibrary.org/obo/GO_0051413 GO:0002446 biolink:BiologicalProcess neutrophil mediated immunity Any process involved in the carrying out of an immune response by a neutrophil. go-plus.json http://purl.obolibrary.org/obo/GO_0002446 GO:0051410 biolink:BiologicalProcess detoxification of nitrogen compound Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances. go-plus.json detoxification of nitrogenous compound|nitric oxide (NO) detoxification http://purl.obolibrary.org/obo/GO_0051410 GO:0002447 biolink:BiologicalProcess eosinophil mediated immunity Any process involved in the carrying out of an immune response by an eosinophil. go-plus.json http://purl.obolibrary.org/obo/GO_0002447 GO:0051411 biolink:MolecularActivity obsolete ALP binding OBSOLETE. Interacting selectively and non-covalently wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band. go-plus.json actinin-associated LIM protein binding|ALP binding http://purl.obolibrary.org/obo/GO_0051411 GO:0002448 biolink:BiologicalProcess mast cell mediated immunity Any process involved in the carrying out of an immune response by a mast cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002448 GO:0002441 biolink:BiologicalProcess histamine secretion involved in inflammatory response The regulated release of histamine by a cell as part of an inflammatory response. go-plus.json histamine secretion involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0002441 GO:0051416 biolink:MolecularActivity obsolete myotilin binding OBSOLETE. Binding to myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C. go-plus.json myotilin binding http://purl.obolibrary.org/obo/GO_0051416 GO:0051417 biolink:BiologicalProcess microtubule nucleation by spindle pole body The 'de novo' formation of a microtubule, mediated by the spindle pole body. go-plus.json microtubule nucleation by SPB|spindle pole body-mediated microtubule nucleation|SPB-mediated microtubule nucleation http://purl.obolibrary.org/obo/GO_0051417 GO:0002442 biolink:BiologicalProcess serotonin secretion involved in inflammatory response The regulated release of serotonin by a cell as part of an inflammatory response. go-plus.json serotonin secretion involved in acute inflammatory response|serotonin release involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002442 GO:0002443 biolink:BiologicalProcess leukocyte mediated immunity Any process involved in the carrying out of an immune response by a leukocyte. go-plus.json immune cell mediated immunity|cell-mediated immune response|leucocyte immune effector process|leucocyte mediated immunity|leukocyte immune effector process|immune cell effector process|cellular immune response http://purl.obolibrary.org/obo/GO_0002443 GO:0051414 biolink:BiologicalProcess response to cortisol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions. go-plus.json response to cortisol stimulus|response to hydrocortisone stimulus http://purl.obolibrary.org/obo/GO_0051414 GO:0051415 biolink:BiologicalProcess microtubule nucleation by interphase microtubule organizing center The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation. go-plus.json interphase microtubule organizing center-mediated microtubule nucleation during interphase|IMTOC-mediated microtubule nucleation during interphase|microtubule nucleation during interphase by IMTOC|interphase microtubule nucleation by interphase microtubule organizing center|interphase microtubule nucleation by interphase microtubule organising centre|microtubule nucleation during interphase by interphase microtubule organizing center http://purl.obolibrary.org/obo/GO_0051415 GO:0002444 biolink:BiologicalProcess myeloid leukocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. go-plus.json myeloid leukocyte immune effector process|myeloid leucocyte immune effector process|myeloid leucocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002444 GO:0051418 biolink:BiologicalProcess microtubule nucleation by microtubule organizing center The 'de novo' formation of a microtubule, mediated by the microtubule organizing center. go-plus.json microtubule nucleation by MTOC|MTOC-mediated microtubule nucleation|microtubule nucleation by microtubule organising centre|microtubule organizing center-mediated microtubule nucleation http://purl.obolibrary.org/obo/GO_0051418 GO:0051419 biolink:MolecularActivity obsolete nebulin binding OBSOLETE. Binding to nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone. go-plus.json nebulin binding http://purl.obolibrary.org/obo/GO_0051419 GO:0002440 biolink:BiologicalProcess production of molecular mediator of immune response The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. go-plus.json production of cellular mediator of immune response http://purl.obolibrary.org/obo/GO_0002440 gocheck_do_not_annotate CHEBI:90337 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-didodecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90337 chebi_ph7_3 CHEBI:90339 biolink:ChemicalSubstance alpha-N-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90339 chebi_ph7_3 CHEBI:90335 biolink:ChemicalSubstance alpha-N-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90335 chebi_ph7_3 CHEBI:90336 biolink:ChemicalSubstance alpha-N-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_90336 chebi_ph7_3 GO:0002449 biolink:BiologicalProcess lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte. go-plus.json cellular immune response|cell-mediated immunity http://purl.obolibrary.org/obo/GO_0002449 GO:0051423 biolink:BiologicalProcess positive regulation of endo-1,4-beta-xylanase activity Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. go-plus.json up-regulation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase activator|upregulation of endo-1,4-beta-xylanase activity|up regulation of endo-1,4-beta-xylanase activity|activation of endo-1,4-beta-xylanase activity|xylanase activator|stimulation of endo-1,4-beta-xylanase activity http://purl.obolibrary.org/obo/GO_0051423 GO:0002456 biolink:BiologicalProcess T cell mediated immunity Any process involved in the carrying out of an immune response by a T cell. go-plus.json cell-mediated immunity|T lymphocyte mediated immunity|cellular immune response|T-cell mediated immunity|T-lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002456 GO:0051424 biolink:MolecularActivity corticotropin-releasing hormone binding Binding to corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland. go-plus.json CRH binding|corticoliberin binding|corticotropin-releasing factor binding|CRF binding http://purl.obolibrary.org/obo/GO_0051424 GO:0002457 biolink:BiologicalProcess T cell antigen processing and presentation The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json T lymphocyte antigen processing and presentation|T-cell antigen processing and presentation|T-lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002457 GO:0002458 biolink:BiologicalProcess peripheral T cell tolerance induction Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus. go-plus.json peripheral T-cell tolerance induction|peripheral T-lymphocyte tolerance induction|peripheral T lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002458 GO:0051421 biolink:BiologicalProcess regulation of endo-1,4-beta-xylanase activity Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. go-plus.json xylanase regulator|endo-1,4-beta-xylanase regulator http://purl.obolibrary.org/obo/GO_0051421 GO:0002459 biolink:BiologicalProcess adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae). go-plus.json adaptive immune response in jawless fish|adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains|adaptive immune response based on somatic recombination of VLR built from LRR domains http://purl.obolibrary.org/obo/GO_0002459 GO:0051422 biolink:BiologicalProcess negative regulation of endo-1,4-beta-xylanase activity Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. go-plus.json xylanase inhibitor|inhibition of endo-1,4-beta-xylanase activity|down regulation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase inhibitor|downregulation of endo-1,4-beta-xylanase activity|down-regulation of endo-1,4-beta-xylanase activity http://purl.obolibrary.org/obo/GO_0051422 GO:0002452 biolink:BiologicalProcess B cell receptor editing The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor. go-plus.json B-lymphocyte receptor editing|B-cell receptor editing|B lymphocyte receptor editing http://purl.obolibrary.org/obo/GO_0002452 GO:0051427 biolink:MolecularActivity hormone receptor binding Binding to a receptor for a hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0051427 GO:0002453 biolink:BiologicalProcess peripheral B cell anergy Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells. go-plus.json peripheral B lymphocyte anergy|peripheral B-lymphocyte anergy|peripheral B-cell anergy http://purl.obolibrary.org/obo/GO_0002453 GO:0051428 biolink:MolecularActivity peptide hormone receptor binding Binding to a receptor for a peptide hormone. go-plus.json polypeptide hormone receptor binding http://purl.obolibrary.org/obo/GO_0051428 goslim_chembl GO:0002454 biolink:BiologicalProcess peripheral B cell deletion The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection. go-plus.json peripheral B lymphocyte deletion|peripheral B-lymphocyte deletion|peripheral B-cell deletion http://purl.obolibrary.org/obo/GO_0002454 GO:0051425 biolink:MolecularActivity PTB domain binding Binding to a phosphotyrosine-binding (PTB) Binding to a phosphotyrosine-bindin domain. go-plus.json phosphotyrosine-interacting domain binding|PID binding http://purl.obolibrary.org/obo/GO_0051425 GO:0002455 biolink:BiologicalProcess humoral immune response mediated by circulating immunoglobulin An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus. go-plus.json circulating immunoglobulin mediated immune response|circulating antibody mediated immune response|humoral defence mechanism|humoral immune response mediated by circulating antibody http://purl.obolibrary.org/obo/GO_0002455 GO:0051426 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0051426 GO:0051429 biolink:MolecularActivity corticotropin-releasing hormone receptor binding Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland. go-plus.json corticotropin-releasing factor receptor binding|corticotropin releasing factor receptor binding|CRF receptor binding|CRH receptor binding|corticotropin releasing factor receptor ligand|CRHR binding http://purl.obolibrary.org/obo/GO_0051429 GO:0002450 biolink:BiologicalProcess B cell antigen processing and presentation The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. go-plus.json B-cell antigen processing and presentation|B-lymphocyte antigen processing and presentation|B lymphocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002450 GO:0002451 biolink:BiologicalProcess peripheral B cell tolerance induction Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue. go-plus.json peripheral B-cell tolerance induction|peripheral B-lymphocyte tolerance induction|peripheral B lymphocyte tolerance induction http://purl.obolibrary.org/obo/GO_0002451 CHEBI:326268 biolink:ChemicalSubstance 1,4-butanediammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_326268 chebi_ph7_3 GO:0051420 biolink:MolecularActivity obsolete nebulette binding OBSOLETE. Binding to nebulette, a 107 kDa protein associated with the I-Z-I complex of cardiac myofibrils. It shows a high degree of homology with skeletal muscle nebulin. go-plus.json nebulette binding http://purl.obolibrary.org/obo/GO_0051420 GO:0002423 biolink:BiologicalProcess natural killer cell mediated immune response to tumor cell An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002423 GO:0051434 biolink:MolecularActivity BH3 domain binding Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0051434 goslim_chembl CHEBI:16380 biolink:ChemicalSubstance vindoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_16380 GO:0002424 biolink:BiologicalProcess T cell mediated immune response to tumor cell An immune response mediated by a T cell triggered in response to the presence of a tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002424 GO:0051435 biolink:MolecularActivity BH4 domain binding Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0051435 CHEBI:16381 biolink:ChemicalSubstance 2'-deoxyribonucleoside 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16381 GO:0002425 biolink:BiologicalProcess tolerance induction in urogenital tract Tolerance induction taking place in the urogenital tract. go-plus.json http://purl.obolibrary.org/obo/GO_0002425 GO:0051432 biolink:MolecularActivity BH1 domain binding Binding to a BH1 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists. go-plus.json http://purl.obolibrary.org/obo/GO_0051432 GO:0002426 biolink:BiologicalProcess immunoglobulin production in mucosal tissue The synthesis and release of immunoglobulin in the mucosal tissue. go-plus.json antibody production in mucosal tissue http://purl.obolibrary.org/obo/GO_0002426 gocheck_do_not_annotate GO:0051433 biolink:MolecularActivity BH2 domain binding Binding to a BH2 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists. go-plus.json http://purl.obolibrary.org/obo/GO_0051433 GO:0051438 biolink:BiologicalProcess regulation of ubiquitin-protein transferase activity Any process that modulates the frequency, rate or extent of ubiquitin transferase activity. go-plus.json regulation of ubiquitin transferase activity|anaphase-promoting complex regulator|SCF complex regulator|ubiquitin-protein transferase regulator|APC regulator|ubiquitin transferase regulator http://purl.obolibrary.org/obo/GO_0051438 GO:0051439 biolink:BiologicalProcess obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle. go-plus.json regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic APC regulator|regulation of ubiquitin-protein ligase activity during mitotic cell cycle|mitotic ubiquitin-protein ligase regulator|mitotic SCF complex regulator|mitotic ubiquitin ligase regulator|mitotic anaphase-promoting complex regulator http://purl.obolibrary.org/obo/GO_0051439 GO:0002420 biolink:BiologicalProcess natural killer cell mediated cytotoxicity directed against tumor cell target The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. go-plus.json NK cell mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002420 GO:0051436 biolink:BiologicalProcess obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle. go-plus.json mitotic ubiquitin ligase inhibitor|down regulation of ubiquitin ligase activity during mitotic cell cycle|anaphase-promoting complex inhibition during mitotic cell cycle|downregulation of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase promoting complex inhibitor|mitotic SCF complex inhibitor|mitotic anaphase promoting complex inhibition|negative regulation of ubiquitin ligase activity during mitotic cell cycle|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle|down-regulation of ubiquitin ligase activity during mitotic cell cycle|anaphase promoting complex inhibition during mitotic cell cycle|APC inhibition during mitotic cell cycle|inhibition of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase-promoting complex inhibitor|mitotic APC inhibition|mitotic APC inhibitor|mitotic anaphase-promoting complex inhibition http://purl.obolibrary.org/obo/GO_0051436 GO:0002421 biolink:BiologicalProcess B cell antigen processing and presentation following pinocytosis B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis. go-plus.json B lymphocyte antigen processing and presentation following pinocytosis|B-cell antigen processing and presentation following pinocytosis|B-lymphocyte antigen processing and presentation following pinocytosis http://purl.obolibrary.org/obo/GO_0002421 GO:0051437 biolink:BiologicalProcess obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition. go-plus.json upregulation of ubiquitin ligase activity during mitotic cell cycle|activation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin ligase activity during mitotic cell cycle|stimulation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle|up regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic ubiquitin ligase activator|up-regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic SCF complex activator http://purl.obolibrary.org/obo/GO_0051437 GO:0002422 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0002422 GO:2000665 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000665 GO:2000666 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000666 GO:2000667 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000667 GO:2000668 biolink:BiologicalProcess regulation of dendritic cell apoptotic process Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process. go-plus.json regulation of dendritic cell apoptosis http://purl.obolibrary.org/obo/GO_2000668 GO:2000669 biolink:BiologicalProcess negative regulation of dendritic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process. go-plus.json negative regulation of dendritic cell apoptosis http://purl.obolibrary.org/obo/GO_2000669 GO:1905600 biolink:BiologicalProcess regulation of receptor-mediated endocytosis involved in cholesterol transport Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport. go-plus.json regulation of receptor-mediated endocytosis of LDL|regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport http://purl.obolibrary.org/obo/GO_1905600 GO:1905601 biolink:BiologicalProcess negative regulation of receptor-mediated endocytosis involved in cholesterol transport Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport. go-plus.json down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down regulation of receptor-mediated endocytosis involved in cholesterol transport|downregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|negative regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|negative regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in intracellular cholesterol transport http://purl.obolibrary.org/obo/GO_1905601 GO:2000660 biolink:BiologicalProcess negative regulation of interleukin-1-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway. go-plus.json negative regulation of interleukin-1 alpha-mediated signaling pathway|negative regulation of interleukin-1-mediated signalling pathway|negative regulation of interleukin-1 beta-mediated signaling pathway|negative regulation of IL-1-mediated signaling pathway|negative regulation of IL-1 alpha-mediated signaling pathway|negative regulation of IL-1 beta-mediated signaling pathway http://purl.obolibrary.org/obo/GO_2000660 GO:1905602 biolink:BiologicalProcess positive regulation of receptor-mediated endocytosis involved in cholesterol transport Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport. go-plus.json activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|upregulation of receptor-mediated endocytosis involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|upregulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|activation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up regulation of receptor-mediated endocytosis involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|activation of receptor-mediated endocytosis involved in cholesterol transport|activation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up-regulation of receptor-mediated endocytosis involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport http://purl.obolibrary.org/obo/GO_1905602 GO:2000661 biolink:BiologicalProcess positive regulation of interleukin-1-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway. go-plus.json positive regulation of interleukin-1-mediated signalling pathway|positive regulation of interleukin-1 beta-mediated signaling pathway|positive regulation of interleukin-1 alpha-mediated signaling pathway|positive regulation of IL-1-mediated signaling pathway|positive regulation of IL-1 alpha-mediated signaling pathway|positive regulation of IL-1 beta-mediated signaling pathway http://purl.obolibrary.org/obo/GO_2000661 CHEBI:90359 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-monododecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90359 chebi_ph7_3 UBERON:0008307 biolink:AnatomicalEntity heart endothelium An endothelium that is part of a heart [Automatically generated definition]. go-plus.json cardiac endothelium http://purl.obolibrary.org/obo/UBERON_0008307 GO:1905603 biolink:BiologicalProcess regulation of blood-brain barrier permeability Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. go-plus.json regulation of blood/brain barrier permeability|regulation of BBB permeability http://purl.obolibrary.org/obo/GO_1905603 GO:2000662 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000662 GO:1905604 biolink:BiologicalProcess negative regulation of blood-brain barrier permeability Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. go-plus.json downregulation of blood/brain barrier permeability|negative regulation of BBB permeability|down-regulation of BBB permeability|downregulation of blood-brain barrier permeability|inhibition of maintenance of permeability of BBB|downregulation of BBB permeability|inhibition of maintenance of permeability of blood-brain barrier|down-regulation of blood/brain barrier permeability|negative regulation of blood/brain barrier permeability|down-regulation of blood-brain barrier permeability http://purl.obolibrary.org/obo/GO_1905604 GO:2000663 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000663 CHEBI:16379 biolink:ChemicalSubstance Co-methyl-Co-5-hydroxybenzimidazolylcob(III)amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16379 chebi_ph7_3 GO:1905605 biolink:BiologicalProcess positive regulation of blood-brain barrier permeability Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. go-plus.json activation of maintenance of permeability of blood-brain barrier|positive regulation of BBB permeability|upregulation of blood/brain barrier permeability|upregulation of blood-brain barrier permeability|up-regulation of blood/brain barrier permeability|upregulation of BBB permeability|up-regulation of blood-brain barrier permeability|activation of maintenance of permeability of BBB|up-regulation of BBB permeability|positive regulation of blood/brain barrier permeability http://purl.obolibrary.org/obo/GO_1905605 GO:2000664 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000664 GO:1905606 biolink:BiologicalProcess regulation of presynapse assembly Any process that modulates the frequency, rate or extent of presynapse assembly. go-plus.json regulation of presynaptic terminal assembly|regulation of presynapse biogenesis http://purl.obolibrary.org/obo/GO_1905606 goslim_synapse CHEBI:16377 biolink:ChemicalSubstance sabinene hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_16377 chebi_ph7_3 GO:1905607 biolink:BiologicalProcess negative regulation of presynapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly. go-plus.json down-regulation of presynaptic terminal assembly|negative regulation of presynaptic terminal assembly|downregulation of presynapse biogenesis|down-regulation of presynapse assembly|inhibition of presynaptic terminal assembly|inhibition of presynapse assembly|negative regulation of presynapse biogenesis|down-regulation of presynapse biogenesis|inhibition of presynapse biogenesis|down regulation of presynaptic terminal assembly|downregulation of presynaptic terminal assembly|down regulation of presynapse assembly|downregulation of presynapse assembly|down regulation of presynapse biogenesis http://purl.obolibrary.org/obo/GO_1905607 CHEBI:16378 biolink:ChemicalSubstance threo-3-methyl-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16378 CHEBI:90356 biolink:ChemicalSubstance dibenzothiophene sulfone go-plus.json http://purl.obolibrary.org/obo/CHEBI_90356 chebi_ph7_3 GO:1905608 biolink:BiologicalProcess positive regulation of presynapse assembly Any process that activates or increases the frequency, rate or extent of presynapse assembly. go-plus.json activation of presynapse assembly|up regulation of presynapse biogenesis|activation of presynapse biogenesis|positive regulation of presynapse biogenesis|up-regulation of presynaptic terminal assembly|up-regulation of presynapse assembly|upregulation of presynaptic terminal assembly|up-regulation of presynapse biogenesis|upregulation of presynapse assembly|up regulation of presynaptic terminal assembly|upregulation of presynapse biogenesis|activation of presynaptic terminal assembly|positive regulation of presynaptic terminal assembly|up regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_1905608 CHEBI:16375 biolink:ChemicalSubstance D-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16375 CHEBI:90357 biolink:ChemicalSubstance beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90357 chebi_ph7_3 GO:1905609 biolink:BiologicalProcess positive regulation of smooth muscle cell-matrix adhesion Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion. go-plus.json up regulation of smooth muscle cell-matrix adhesion|upregulation of smooth muscle cell-matrix adhesion|activation of smooth muscle cell-matrix adhesion|up-regulation of smooth muscle cell-matrix adhesion http://purl.obolibrary.org/obo/GO_1905609 CHEBI:90358 biolink:ChemicalSubstance beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90358 chebi_ph7_3 GO:0051430 biolink:MolecularActivity corticotropin-releasing hormone receptor 1 binding Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system. go-plus.json type 1 corticotropin-releasing factor receptor binding|type 1 corticotropin releasing factor receptor binding|type 1 corticotropin releasing factor receptor ligand|CRHR1 binding http://purl.obolibrary.org/obo/GO_0051430 GO:0002427 biolink:BiologicalProcess mucosal tolerance induction Tolerance induction taking place in the mucosal tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0002427 CHEBI:16373 biolink:ChemicalSubstance (S)-3-(imidazol-5-yl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16373 GO:0002428 biolink:BiologicalProcess antigen processing and presentation of peptide antigen via MHC class Ib The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family. go-plus.json peptide antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0002428 GO:0051431 biolink:MolecularActivity corticotropin-releasing hormone receptor 2 binding Binding to a corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery. go-plus.json type 2 corticotropin-releasing factor receptor binding|type 2 corticotropin releasing factor receptor binding|type 2 corticotropin releasing factor receptor ligand|CRHR2 binding http://purl.obolibrary.org/obo/GO_0051431 CHEBI:16374 biolink:ChemicalSubstance menaquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16374 chebi_ph7_3 GO:0002429 biolink:BiologicalProcess immune response-activating cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response. go-plus.json immune response-activating cell surface receptor signalling pathway|activation of immune response by cell surface receptor signaling pathway http://purl.obolibrary.org/obo/GO_0002429 CHEBI:16372 biolink:ChemicalSubstance 4,5alpha-dihydrocortisone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16372 chebi_ph7_3 GO:0002434 biolink:BiologicalProcess immune complex clearance A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. go-plus.json http://purl.obolibrary.org/obo/GO_0002434 GO:0051445 biolink:BiologicalProcess regulation of meiotic cell cycle Any process that modulates the rate or extent of progression through the meiotic cell cycle. go-plus.json modulation of meiotic cell cycle progression|regulation of progression through meiotic cell cycle|meiotic cell cycle regulator|meiotic cell cycle regulation|regulation of meiotic cell cycle progression|meiotic cell cycle modulation http://purl.obolibrary.org/obo/GO_0051445 PR:000013164 biolink:Protein pancreatic prohormone A protein that is a translation product of the human PPY gene or a 1:1 ortholog thereof. go-plus.json PP|obinepitide|PPY|PNP|pancreatic polypeptide http://purl.obolibrary.org/obo/PR_000013164 GO:0002435 biolink:BiologicalProcess immune complex clearance by erythrocytes The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation. Wikipedia:Immune_complex go-plus.json immune complex clearance by RBCs|immune complex clearance by red blood cells http://purl.obolibrary.org/obo/GO_0002435 GO:0051446 biolink:BiologicalProcess positive regulation of meiotic cell cycle Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. go-plus.json stimulation of progression through meiotic cell cycle|positive regulation of progression through meiotic cell cycle|up-regulation of progression through meiotic cell cycle|activation of progression through meiotic cell cycle|up regulation of progression through meiotic cell cycle|positive regulation of meiotic cell cycle progression|upregulation of progression through meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051446 CHEBI:16370 biolink:ChemicalSubstance dihydrophloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16370 GO:0051443 biolink:BiologicalProcess positive regulation of ubiquitin-protein transferase activity Any process that activates, maintains or increases the rate of ubiquitin transferase activity. go-plus.json stimulation of ubiquitin transferase activity|up-regulation of ubiquitin transferase activity|activation of ubiquitin transferase activity|up regulation of ubiquitin ligase activity|positive regulation of ubiquitin transferase activity|ubiquitin transferase activator|anaphase promoting complex activator|APC activator|APC activation|upregulation of ubiquitin transferase activity|anaphase-promoting complex activator|SCF complex activator http://purl.obolibrary.org/obo/GO_0051443 GO:0002436 biolink:BiologicalProcess immune complex clearance by monocytes and macrophages The process of immune complex clearance by monocytes or macrophages. go-plus.json http://purl.obolibrary.org/obo/GO_0002436 GO:0051444 biolink:BiologicalProcess negative regulation of ubiquitin-protein transferase activity Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity. go-plus.json anaphase-promoting complex inhibition|negative regulation of ubiquitin transferase activity|anaphase-promoting complex inhibitor|SCF complex inhibitor|down-regulation of ubiquitin transferase activity|APC inhibition|anaphase promoting complex inhibition|downregulation of ubiquitin transferase activity|down regulation of ubiquitin transferase activity|ubiquitin transferase inhibitor|inhibition of ubiquitin transferase activity|APC inhibitor|anaphase promoting complex inhibitor http://purl.obolibrary.org/obo/GO_0051444 GO:0002437 biolink:BiologicalProcess inflammatory response to antigenic stimulus An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes. go-plus.json http://purl.obolibrary.org/obo/GO_0002437 GO:0002430 biolink:BiologicalProcess complement receptor mediated signaling pathway A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway. go-plus.json complement receptor mediated signalling pathway|immune response-regulating cell surface receptor signalling pathway http://purl.obolibrary.org/obo/GO_0002430 GO:0051449 biolink:MolecularActivity thyrotropin-releasing hormone binding Binding to thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system. go-plus.json thyrotropin releasing hormone binding http://purl.obolibrary.org/obo/GO_0051449 GO:0002431 biolink:BiologicalProcess Fc receptor mediated stimulatory signaling pathway A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json Fc-receptor mediated stimulatory signaling pathway|Fc receptor mediated stimulatory signalling pathway http://purl.obolibrary.org/obo/GO_0002431 GO:0051447 biolink:BiologicalProcess negative regulation of meiotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. go-plus.json negative regulation of progression through meiotic cell cycle|down-regulation of progression through meiotic cell cycle|negative regulation of meiotic cell cycle progression|downregulation of progression through meiotic cell cycle|down regulation of progression through meiotic cell cycle|inhibition of progression through meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051447 GO:0002432 biolink:BiologicalProcess granuloma formation The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. go-plus.json http://purl.obolibrary.org/obo/GO_0002432 GO:0002433 biolink:BiologicalProcess immune response-regulating cell surface receptor signaling pathway involved in phagocytosis An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes. go-plus.json phagocytosis triggered by activation of immune response cell surface activating receptor|immune response-regulating cell surface receptor signalling pathway involved in phagocytosis http://purl.obolibrary.org/obo/GO_0002433 GO:0051448 biolink:MolecularActivity gonadotropin-releasing hormone binding Binding to gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. go-plus.json gonadotrophin releasing hormone binding|GnRH binding http://purl.obolibrary.org/obo/GO_0051448 GO:2000676 biolink:BiologicalProcess positive regulation of type B pancreatic cell apoptotic process Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process. go-plus.json positive regulation of pancreatic B cell apoptosis|positive regulation of type B pancreatic cell apoptosis|positive regulation of pancreatic beta cell apoptosis http://purl.obolibrary.org/obo/GO_2000676 GO:2000677 biolink:BiologicalProcess regulation of transcription regulatory region DNA binding Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_2000677 GO:2000678 biolink:BiologicalProcess negative regulation of transcription regulatory region DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_2000678 GO:2000679 biolink:BiologicalProcess positive regulation of transcription regulatory region DNA binding Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_2000679 GO:1905610 biolink:BiologicalProcess regulation of mRNA cap binding Any process that modulates the frequency, rate or extent of mRNA cap binding. go-plus.json http://purl.obolibrary.org/obo/GO_1905610 GO:1905611 biolink:BiologicalProcess negative regulation of mRNA cap binding Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding. go-plus.json down-regulation of mRNA cap binding|downregulation of mRNA cap binding|down regulation of mRNA cap binding|inhibition of mRNA cap binding http://purl.obolibrary.org/obo/GO_1905611 GO:2000670 biolink:BiologicalProcess positive regulation of dendritic cell apoptotic process Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process. go-plus.json positive regulation of dendritic cell apoptosis http://purl.obolibrary.org/obo/GO_2000670 GO:2000671 biolink:BiologicalProcess regulation of motor neuron apoptotic process Any process that modulates the frequency, rate or extent of motor neuron apoptotic process. go-plus.json regulation of motoneuron apoptosis|regulation of motor neuron apoptosis http://purl.obolibrary.org/obo/GO_2000671 GO:1905612 biolink:BiologicalProcess positive regulation of mRNA cap binding Any process that activates or increases the frequency, rate or extent of mRNA cap binding. go-plus.json up regulation of mRNA cap binding|upregulation of mRNA cap binding|up-regulation of mRNA cap binding|activation of mRNA cap binding http://purl.obolibrary.org/obo/GO_1905612 GO:2000672 biolink:BiologicalProcess negative regulation of motor neuron apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. go-plus.json negative regulation of motor neuron apoptosis|negative regulation of motoneuron apoptosis http://purl.obolibrary.org/obo/GO_2000672 GO:1905613 biolink:BiologicalProcess regulation of developmental vegetative growth Any process that modulates the frequency, rate or extent of developmental vegetative growth. go-plus.json http://purl.obolibrary.org/obo/GO_1905613 GO:1905614 biolink:BiologicalProcess negative regulation of developmental vegetative growth Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth. go-plus.json down-regulation of developmental vegetative growth|inhibition of developmental vegetative growth|down regulation of developmental vegetative growth|downregulation of developmental vegetative growth http://purl.obolibrary.org/obo/GO_1905614 GO:2000673 biolink:BiologicalProcess positive regulation of motor neuron apoptotic process Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process. go-plus.json positive regulation of motor neuron apoptosis|positive regulation of motoneuron apoptosis http://purl.obolibrary.org/obo/GO_2000673 CHEBI:16368 biolink:ChemicalSubstance 6-hydroxymellein go-plus.json http://purl.obolibrary.org/obo/CHEBI_16368 chebi_ph7_3 GO:2000674 biolink:BiologicalProcess regulation of type B pancreatic cell apoptotic process Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process. go-plus.json regulation of type B pancreatic cell apoptosis|regulation of pancreatic beta cell apoptosis|regulation of pancreatic B cell apoptosis http://purl.obolibrary.org/obo/GO_2000674 GO:1905615 biolink:BiologicalProcess positive regulation of developmental vegetative growth Any process that activates or increases the frequency, rate or extent of developmental vegetative growth. go-plus.json up-regulation of developmental vegetative growth|upregulation of developmental vegetative growth|up regulation of developmental vegetative growth|activation of developmental vegetative growth http://purl.obolibrary.org/obo/GO_1905615 GO:1905616 biolink:BiologicalProcess regulation of miRNA mediated inhibition of translation Any process that modulates the frequency, rate or extent of miRNA mediated inhibition of translation. go-plus.json regulation of down-regulation of translation involved in gene silencing by miRNA|regulation of miRNA-mediated gene silencing, negative regulation of translation|regulation of inhibition of translation involved in gene silencing by miRNA|regulation of gene silencing by miRNA, negative regulation of translation|regulation of down regulation of translation involved in gene silencing by miRNA|regulation of negative regulation of translation involved in gene silencing by microRNA|regulation of downregulation of translation involved in gene silencing by miRNA http://purl.obolibrary.org/obo/GO_1905616 GO:2000675 biolink:BiologicalProcess negative regulation of type B pancreatic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process. go-plus.json negative regulation of pancreatic B cell apoptosis|negative regulation of type B pancreatic cell apoptosis|negative regulation of pancreatic beta cell apoptosis http://purl.obolibrary.org/obo/GO_2000675 CHEBI:16369 biolink:ChemicalSubstance 5-dehydro-4-deoxy-D-glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16369 CHEBI:41336 biolink:ChemicalSubstance 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_41336 GO:1905617 biolink:BiologicalProcess negative regulation of miRNA mediated inhibition of translation Any process that stops, prevents or reduces the frequency, rate or extent of miRNA mediated inhibition of translation. go-plus.json downregulation of down-regulation of translation involved in gene silencing by miRNA|downregulation of downregulation of translation involved in gene silencing by miRNA|down regulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of gene silencing by miRNA, negative regulation of translation|down regulation of down-regulation of translation involved in gene silencing by miRNA|inhibition of down-regulation of translation involved in gene silencing by miRNA|negative regulation of negative regulation of translation involved in gene silencing by microRNA|inhibition of inhibition of translation involved in gene silencing by miRNA|down-regulation of negative regulation of translation involved in gene silencing by microRNA|downregulation of miRNA-mediated gene silencing, negative regulation of translation|down-regulation of miRNA mediated inhibition of translation|down-regulation of downregulation of translation involved in gene silencing by miRNA|down-regulation of down regulation of translation involved in gene silencing by miRNA|negative regulation of down regulation of translation involved in gene silencing by miRNA|negative regulation of downregulation of translation involved in gene silencing by miRNA|inhibition of negative regulation of translation involved in gene silencing by microRNA|down regulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of miRNA-mediated gene silencing, negative regulation of translation|negative regulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of downregulation of translation involved in gene silencing by miRNA|downregulation of inhibition of translation involved in gene silencing by miRNA|down regulation of gene silencing by miRNA, negative regulation of translation|downregulation of miRNA mediated inhibition of translation|downregulation of down regulation of translation involved in gene silencing by miRNA|downregulation of gene silencing by miRNA, negative regulation of translation|down regulation of miRNA mediated inhibition of translation|inhibition of miRNA mediated inhibition of translation|down-regulation of down-regulation of translation involved in gene silencing by miRNA|down regulation of down regulation of translation involved in gene silencing by miRNA|negative regulation of down-regulation of translation involved in gene silencing by miRNA|inhibition of down regulation of translation involved in gene silencing by miRNA|down regulation of negative regulation of translation involved in gene silencing by microRNA|negative regulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of inhibition of translation involved in gene silencing by miRNA|inhibition of miRNA-mediated gene silencing, negative regulation of translation|downregulation of negative regulation of translation involved in gene silencing by microRNA|down-regulation of gene silencing by miRNA, negative regulation of translation|negative regulation of gene silencing by miRNA, negative regulation of translation|down regulation of downregulation of translation involved in gene silencing by miRNA http://purl.obolibrary.org/obo/GO_1905617 CHEBI:16366 biolink:ChemicalSubstance anthocyanidin cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_16366 chebi_ph7_3 GO:1905618 biolink:BiologicalProcess positive regulation of miRNA mediated inhibition of translation Any process that activates or increases the frequency, rate or extent of miRNA mediated inhibition of translation. go-plus.json upregulation of miRNA-mediated gene silencing, negative regulation of translation|up regulation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of miRNA mediated inhibition of translation|activation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of inhibition of translation involved in gene silencing by miRNA|positive regulation of negative regulation of translation involved in gene silencing by microRNA|activation of miRNA mediated inhibition of translation|up-regulation of down regulation of translation involved in gene silencing by miRNA|up-regulation of gene silencing by miRNA, negative regulation of translation|up regulation of downregulation of translation involved in gene silencing by miRNA|activation of down regulation of translation involved in gene silencing by miRNA|positive regulation of downregulation of translation involved in gene silencing by miRNA|activation of downregulation of translation involved in gene silencing by miRNA|upregulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of inhibition of translation involved in gene silencing by miRNA|positive regulation of miRNA-mediated gene silencing, negative regulation of translation|up-regulation of negative regulation of translation involved in gene silencing by microRNA|upregulation of gene silencing by miRNA, negative regulation of translation|up regulation of miRNA mediated inhibition of translation|positive regulation of down regulation of translation involved in gene silencing by miRNA|up-regulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of down regulation of translation involved in gene silencing by miRNA|activation of miRNA-mediated gene silencing, negative regulation of translation|up-regulation of downregulation of translation involved in gene silencing by miRNA|activation of down-regulation of translation involved in gene silencing by miRNA|up regulation of inhibition of translation involved in gene silencing by miRNA|upregulation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of miRNA-mediated gene silencing, negative regulation of translation|positive regulation of inhibition of translation involved in gene silencing by miRNA|up regulation of gene silencing by miRNA, negative regulation of translation|upregulation of miRNA mediated inhibition of translation|positive regulation of gene silencing by miRNA, negative regulation of translation|activation of gene silencing by miRNA, negative regulation of translation|upregulation of downregulation of translation involved in gene silencing by miRNA|upregulation of down regulation of translation involved in gene silencing by miRNA|positive regulation of down-regulation of translation involved in gene silencing by miRNA|activation of inhibition of translation involved in gene silencing by miRNA|up regulation of down-regulation of translation involved in gene silencing by miRNA http://purl.obolibrary.org/obo/GO_1905618 CHEBI:16367 biolink:ChemicalSubstance N(tele)-methyl-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_16367 chebi_ph7_3 GO:1905619 biolink:BiologicalProcess regulation of alpha-(1->3)-fucosyltransferase activity Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity. go-plus.json regulation of alpha(1,3)-fucosyltransferase activity|regulation of alpha-(1,3)-fucosyltransferase activity|regulation of alpha-1,3-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_1905619 CHEBI:16364 biolink:ChemicalSubstance pyridine-2,5-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16364 chebi_ph7_3 CHEBI:16365 biolink:ChemicalSubstance quinolin-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_16365 chebi_ph7_3 GO:0051441 biolink:BiologicalProcess obsolete positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle. go-plus.json meiotic anaphase promoting complex activator|meiotic APC activator|upregulation of ubiquitin ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle|activation of anaphase-promoting complex activity involved in meiotic cell cycle|anaphase promoting complex activation during meiotic cell cycle|APC activation during meiotic cell cycle|positive regulation of ubiquitin ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC activation|meiotic anaphase-promoting complex activator|stimulation of ubiquitin ligase activity during meiotic cell cycle|up regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic SCF complex activator|positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle|meiotic anaphase promoting complex activation|activation of ubiquitin ligase activity of APC during meiotic cell cycle|activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle|activation of anaphase-promoting complex activity during meiotic cell cycle|up-regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic ubiquitin ligase activator|anaphase-promoting complex activation during meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051441 CHEBI:90340 biolink:ChemicalSubstance 1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90340 chebi_ph7_3 CHEBI:16362 biolink:ChemicalSubstance D-aldose go-plus.json http://purl.obolibrary.org/obo/CHEBI_16362 GO:0002438 biolink:BiologicalProcess acute inflammatory response to antigenic stimulus An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0002438 GO:0051442 biolink:BiologicalProcess obsolete negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle. go-plus.json meiotic ubiquitin ligase inhibitor|down regulation of ubiquitin ligase activity during meiotic cell cycle|anaphase-promoting complex inhibition during meiotic cell cycle|downregulation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC inhibitor|meiotic anaphase promoting complex inhibitor|meiotic anaphase-promoting complex inhibition|negative regulation of ubiquitin ligase activity during meiotic cell cycle|down-regulation of ubiquitin ligase activity during meiotic cell cycle|APC inhibition during meiotic cell cycle|anaphase promoting complex inhibition during meiotic cell cycle|inhibition of ubiquitin ligase activity during meiotic cell cycle|meiotic anaphase-promoting complex inhibitor|meiotic SCF complex inhibitor|meiotic APC inhibition|meiotic anaphase promoting complex inhibition http://purl.obolibrary.org/obo/GO_0051442 GO:0002439 biolink:BiologicalProcess chronic inflammatory response to antigenic stimulus A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual. go-plus.json http://purl.obolibrary.org/obo/GO_0002439 CHEBI:16363 biolink:ChemicalSubstance alpha-santonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_16363 chebi_ph7_3 CHEBI:90342 biolink:ChemicalSubstance 2,3-di-O-dodecanoyl-1-O-beta-D-galactopyranosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_90342 chebi_ph7_3 GO:0051440 biolink:BiologicalProcess obsolete regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle. go-plus.json meiotic anaphase-promoting complex regulator|meiotic SCF complex regulator|regulation of ubiquitin ligase activity during meiotic cell cycle|regulation of ubiquitin-protein ligase activity during meiotic cell cycle|meiotic ubiquitin-protein ligase regulator|meiotic APC regulator|meiotic ubiquitin ligase regulator http://purl.obolibrary.org/obo/GO_0051440 GO:0002401 biolink:BiologicalProcess tolerance induction in mucosal-associated lymphoid tissue Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT). go-plus.json tolerance induction in MALT http://purl.obolibrary.org/obo/GO_0002401 GO:0051456 biolink:BiologicalProcess attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs. go-plus.json meiotic bipolar attachment|attachment of spindle microtubules to kinetochore during meiosis II|attachment of spindle microtubules to kinetochore involved in meiosis II http://purl.obolibrary.org/obo/GO_0051456 GO:0002402 biolink:BiologicalProcess B cell tolerance induction in mucosal-associated lymphoid tissue Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells. go-plus.json B cell tolerance induction in MALT http://purl.obolibrary.org/obo/GO_0002402 GO:0051457 biolink:BiologicalProcess maintenance of protein location in nucleus Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus. go-plus.json nuclear protein retention|maintenance of nuclear protein localization|maintenance of protein localization in nucleus|protein sequestration in nucleus|nuclear protein sequestering|nuclear protein sequestration|protein storage in nucleus|protein-nuclear retention|storage of protein in nucleus|maintenance of protein location in cell nucleus|protein retention in nucleus|sequestration of protein in nucleus http://purl.obolibrary.org/obo/GO_0051457 GO:0002403 biolink:BiologicalProcess T cell tolerance induction in mucosal-associated lymphoid tissue Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells. go-plus.json T cell tolerance induction in MALT http://purl.obolibrary.org/obo/GO_0002403 GO:0051454 biolink:BiologicalProcess intracellular pH elevation Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion. go-plus.json intracellular alkalinization|cellular alkalinization|elevation of cellular pH|cell pH elevation|pH elevation in cell http://purl.obolibrary.org/obo/GO_0051454 GO:0051455 biolink:BiologicalProcess monopolar spindle attachment to meiosis I kinetochore The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs. go-plus.json monopolar attachment|attachment of spindle microtubules to kinetochore involved in meiosis I|attachment of spindle microtubules to kinetochore during meiosis I|sister kinetochore mono-orientation|attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation http://purl.obolibrary.org/obo/GO_0051455 GO:0002404 biolink:BiologicalProcess antigen sampling in mucosal-associated lymphoid tissue The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue. go-plus.json antigen sampling in MALT|antigen transport in mucosal-associated lymphoid tissue|antigen transport in MALT http://purl.obolibrary.org/obo/GO_0002404 GO:0051458 biolink:BiologicalProcess corticotropin secretion The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus. go-plus.json ACTH secretion|adrenotropic hormone secretion|adrenocorticotropic hormone secretion|corticotropic hormone secretion|adrenotropin secretion|adrenocorticotropin secretion http://purl.obolibrary.org/obo/GO_0051458 GO:0051459 biolink:BiologicalProcess regulation of corticotropin secretion Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. go-plus.json regulation of adrenotropin hormone secretion|regulation of corticotropic hormone secretion|regulation of adrenocorticotropic hormone secretion|regulation of adrenotropin secretion|regulation of ACTH secretion|regulation of adrenocorticotropin secretion http://purl.obolibrary.org/obo/GO_0051459 GO:0002400 biolink:BiologicalProcess tolerance induction in nasopharyngeal-associated lymphoid tissue Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT). go-plus.json tolerance induction in NALT|nasal tolerance http://purl.obolibrary.org/obo/GO_0002400 GO:2000687 biolink:BiologicalProcess obsolete negative regulation of rubidium ion transmembrane transporter activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity. go-plus.json negative regulation of Rb+ transmembrane transporter activity|negative regulation of rubidium transmembrane transporter activity|negative regulation of rubidium cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_2000687 GO:2000688 biolink:BiologicalProcess obsolete positive regulation of rubidium ion transmembrane transporter activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity. go-plus.json positive regulation of Rb+ transmembrane transporter activity|positive regulation of rubidium transmembrane transporter activity|positive regulation of rubidium cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_2000688 CHEBI:31997 biolink:ChemicalSubstance N,N-dimethylethanolamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31997 GO:2000689 biolink:BiologicalProcess actomyosin contractile ring assembly actin filament organization An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis. go-plus.json regulation of actin filament localization of cytokinesis, contractile ring assembly|actin filament organization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin ring formation|actin filament organisation of contractile ring assembly|actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament localization of constriction ring assembly|actin filament organization of cytokinesis, actomyosin ring formation|actin filament organization involved in cytokinetic actomyosin contractile ring assembly|actin filament organisation of cytokinesis, contractile ring assembly|actin filament organization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin contractile ring formation|actin filament organization of cytokinesis, contractile ring assembly|actin filament organisation of constriction ring assembly|regulation of actin filament localization of contractile ring assembly|actin filament organisation of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament localization of cytokinesis, actomyosin ring formation|regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|actin filament organization of cytokinesis, actomyosin contractile ring formation|actin filament organization of constriction ring assembly|actin filament organization of contractile ring assembly http://purl.obolibrary.org/obo/GO_2000689 CHEBI:31998 biolink:ChemicalSubstance N-acylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_31998 chebi_ph7_3 CHEBI:41321 biolink:ChemicalSubstance cholesterol sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_41321 GO:1905630 biolink:BiologicalProcess response to glyceraldehyde Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905630 GO:1905620 biolink:BiologicalProcess negative regulation of alpha-(1->3)-fucosyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity. go-plus.json down-regulation of alpha(1,3)-fucosyltransferase activity|negative regulation of alpha(1,3)-fucosyltransferase activity|down regulation of alpha-(1,3)-fucosyltransferase activity|down regulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha-(1,3)-fucosyltransferase activity|downregulation of alpha-(1->3)-fucosyltransferase activity|downregulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha(1,3)-fucosyltransferase activity|down regulation of alpha-(1->3)-fucosyltransferase activity|inhibition of alpha-(1->3)-fucosyltransferase activity|negative regulation of alpha-(1,3)-fucosyltransferase activity|down regulation of alpha(1,3)-fucosyltransferase activity|down-regulation of alpha-(1,3)-fucosyltransferase activity|negative regulation of alpha-1,3-fucosyltransferase activity|inhibition of alpha(1,3)-fucosyltransferase activity|down-regulation of alpha-1,3-fucosyltransferase activity|inhibition of alpha-(1,3)-fucosyltransferase activity|inhibition of alpha-1,3-fucosyltransferase activity|down-regulation of alpha-(1->3)-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_1905620 GO:1905621 biolink:BiologicalProcess positive regulation of alpha-(1->3)-fucosyltransferase activity Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity. go-plus.json up regulation of alpha-(1->3)-fucosyltransferase activity|positive regulation of alpha(1,3)-fucosyltransferase activity|up regulation of alpha(1,3)-fucosyltransferase activity|up regulation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha-1,3-fucosyltransferase activity|positive regulation of alpha-(1,3)-fucosyltransferase activity|activation of alpha-(1,3)-fucosyltransferase activity|activation of alpha-1,3-fucosyltransferase activity|positive regulation of alpha-1,3-fucosyltransferase activity|upregulation of alpha-(1->3)-fucosyltransferase activity|upregulation of alpha(1,3)-fucosyltransferase activity|up-regulation of alpha-(1,3)-fucosyltransferase activity|up-regulation of alpha-(1->3)-fucosyltransferase activity|up-regulation of alpha-1,3-fucosyltransferase activity|activation of alpha-(1->3)-fucosyltransferase activity|up-regulation of alpha(1,3)-fucosyltransferase activity|activation of alpha(1,3)-fucosyltransferase activity|upregulation of alpha-(1,3)-fucosyltransferase activity|upregulation of alpha-1,3-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_1905621 GO:2000680 biolink:BiologicalProcess obsolete regulation of rubidium ion transport OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transport. go-plus.json regulation of rubidium cation transport|regulation of Rb+ transport http://purl.obolibrary.org/obo/GO_2000680 GO:2000681 biolink:BiologicalProcess obsolete negative regulation of rubidium ion transport OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport. go-plus.json negative regulation of rubidium cation transport|negative regulation of Rb+ transport http://purl.obolibrary.org/obo/GO_2000681 GO:1905622 biolink:BiologicalProcess negative regulation of leaf development Any process that stops, prevents or reduces the frequency, rate or extent of leaf development. go-plus.json down-regulation of leaf development|downregulation of leaf development|down regulation of leaf development|inhibition of leaf development http://purl.obolibrary.org/obo/GO_1905622 GO:1905623 biolink:BiologicalProcess positive regulation of leaf development Any process that activates or increases the frequency, rate or extent of leaf development. go-plus.json up-regulation of leaf development|activation of leaf development|up regulation of leaf development|upregulation of leaf development http://purl.obolibrary.org/obo/GO_1905623 GO:2000682 biolink:BiologicalProcess obsolete positive regulation of rubidium ion transport OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transport. go-plus.json positive regulation of rubidium cation transport|positive regulation of Rb+ transport http://purl.obolibrary.org/obo/GO_2000682 GO:1905624 biolink:BiologicalProcess regulation of L-methionine import across plasma membrane Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905624 GO:2000683 biolink:BiologicalProcess regulation of cellular response to X-ray Any process that modulates the frequency, rate or extent of cellular response to X-ray. go-plus.json regulation of cellular response to X-ray radiation stimulus http://purl.obolibrary.org/obo/GO_2000683 GO:1905625 biolink:BiologicalProcess negative regulation of L-methionine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905625 GO:2000684 biolink:BiologicalProcess negative regulation of cellular response to X-ray Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray. go-plus.json negative regulation of cellular response to X-ray radiation stimulus http://purl.obolibrary.org/obo/GO_2000684 GO:2000685 biolink:BiologicalProcess positive regulation of cellular response to X-ray Any process that activates or increases the frequency, rate or extent of cellular response to X-ray. go-plus.json positive regulation of cellular response to X-ray radiation stimulus http://purl.obolibrary.org/obo/GO_2000685 GO:1905626 biolink:BiologicalProcess positive regulation of L-methionine import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1905626 GO:2000686 biolink:BiologicalProcess obsolete regulation of rubidium ion transmembrane transporter activity OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transmembrane transporter activity. go-plus.json regulation of rubidium cation transmembrane transporter activity|regulation of rubidium transmembrane transporter activity|regulation of Rb+ transmembrane transporter activity http://purl.obolibrary.org/obo/GO_2000686 GO:1905627 biolink:BiologicalProcess regulation of serotonin biosynthetic process Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. go-plus.json regulation of serotonin biosynthesis|regulation of serotonin anabolism|regulation of serotonin synthesis|regulation of serotonin formation http://purl.obolibrary.org/obo/GO_1905627 CHEBI:111763 biolink:ChemicalSubstance N-demethylindolmycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_111763 GO:1905628 biolink:BiologicalProcess negative regulation of serotonin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. go-plus.json negative regulation of serotonin biosynthesis|down-regulation of serotonin biosynthetic process|down-regulation of serotonin biosynthesis|negative regulation of serotonin synthesis|down-regulation of serotonin synthesis|negative regulation of serotonin formation|down-regulation of serotonin formation|inhibition of serotonin anabolism|downregulation of serotonin biosynthetic process|downregulation of serotonin biosynthesis|inhibition of serotonin synthesis|inhibition of serotonin formation|down regulation of serotonin biosynthetic process|down regulation of serotonin biosynthesis|inhibition of serotonin biosynthetic process|inhibition of serotonin biosynthesis|down regulation of serotonin anabolism|down regulation of serotonin synthesis|downregulation of serotonin anabolism|down regulation of serotonin formation|downregulation of serotonin synthesis|downregulation of serotonin formation|negative regulation of serotonin anabolism|down-regulation of serotonin anabolism http://purl.obolibrary.org/obo/GO_1905628 GO:0002409 biolink:BiologicalProcess Langerhans cell chemotaxis The movement of a Langerhans cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002409 CHEBI:16399 biolink:ChemicalSubstance N(3)-oxalyl-L-2,3-diaminopropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16399 GO:1905629 biolink:BiologicalProcess positive regulation of serotonin biosynthetic process Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. go-plus.json positive regulation of serotonin synthesis|up regulation of serotonin formation|activation of serotonin formation|positive regulation of serotonin formation|positive regulation of serotonin biosynthesis|up-regulation of serotonin anabolism|up regulation of serotonin biosynthetic process|up regulation of serotonin biosynthesis|up-regulation of serotonin synthesis|up-regulation of serotonin formation|upregulation of serotonin anabolism|upregulation of serotonin biosynthesis|upregulation of serotonin biosynthetic process|upregulation of serotonin synthesis|upregulation of serotonin formation|up regulation of serotonin anabolism|up-regulation of serotonin biosynthetic process|activation of serotonin anabolism|up-regulation of serotonin biosynthesis|activation of serotonin biosynthesis|activation of serotonin biosynthetic process|positive regulation of serotonin anabolism|up regulation of serotonin synthesis|activation of serotonin synthesis http://purl.obolibrary.org/obo/GO_1905629 CHEBI:16397 biolink:ChemicalSubstance formamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16397 chebi_ph7_3 CHEBI:90379 biolink:ChemicalSubstance beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90379 chebi_ph7_3 CHEBI:16398 biolink:ChemicalSubstance D-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16398 GO:0051452 biolink:BiologicalProcess intracellular pH reduction Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion. go-plus.json cellular acidification|cell pH reduction|intracellular acidification|reduction of cellular pH|reduction of pH in cell http://purl.obolibrary.org/obo/GO_0051452 GO:0002405 biolink:BiologicalProcess antigen sampling by dendritic cells in mucosal-associated lymphoid tissue The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue. go-plus.json antigen sampling by dendritic cells in MALT http://purl.obolibrary.org/obo/GO_0002405 CHEBI:16395 biolink:ChemicalSubstance N-acetoxy-1,1'-biphenyl-4-amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16395 chebi_ph7_3 GO:0051453 biolink:BiologicalProcess regulation of intracellular pH Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion. go-plus.json regulation of cell pH|cellular pH regulation|cell pH regulation|pH regulation in cell http://purl.obolibrary.org/obo/GO_0051453 GO:0002406 biolink:BiologicalProcess antigen sampling by M cells in mucosal-associated lymphoid tissue The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue. go-plus.json antigen sampling by M cells in MALT http://purl.obolibrary.org/obo/GO_0002406 GO:0051450 biolink:BiologicalProcess myoblast proliferation The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0051450 GO:0002407 biolink:BiologicalProcess dendritic cell chemotaxis The movement of a dendritic cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002407 CHEBI:16393 biolink:ChemicalSubstance sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16393 CHEBI:16394 biolink:ChemicalSubstance N-methylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16394 GO:0002408 biolink:BiologicalProcess myeloid dendritic cell chemotaxis The movement of a myeloid dendritic cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002408 CHEBI:90376 biolink:ChemicalSubstance beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90376 chebi_ph7_3 GO:0051451 biolink:BiologicalProcess myoblast migration The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0051451 GO:0002412 biolink:BiologicalProcess antigen transcytosis by M cells in mucosal-associated lymphoid tissue The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT. go-plus.json antigen transport by M cells in MALT|antigen transport by M cells in mucosal-associated lymphoid tissue|antigen transcytosis by M cells in MALT http://purl.obolibrary.org/obo/GO_0002412 GO:0051467 biolink:BiologicalProcess detection of steroid hormone stimulus The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0051467 CHEBI:16392 biolink:ChemicalSubstance D-xylono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_16392 chebi_ph7_3 GO:0002413 biolink:BiologicalProcess tolerance induction to tumor cell A process of tolerance induction which leads to immunological tolerance of a tumor. go-plus.json http://purl.obolibrary.org/obo/GO_0002413 GO:0051468 biolink:BiologicalProcess detection of glucocorticoid hormone stimulus The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. go-plus.json http://purl.obolibrary.org/obo/GO_0051468 GO:0051465 biolink:BiologicalProcess negative regulation of corticotropin-releasing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell. go-plus.json inhibition of corticotropin-releasing hormone secretion|negative regulation of CRH secretion|negative regulation of CRF secretion|down regulation of corticotropin-releasing hormone secretion|downregulation of corticotropin-releasing hormone secretion|negative regulation of corticotropin-releasing factor secretion|down-regulation of corticotropin-releasing hormone secretion http://purl.obolibrary.org/obo/GO_0051465 GO:0002414 biolink:BiologicalProcess immunoglobulin transcytosis in epithelial cells The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0002414 CHEBI:90360 biolink:ChemicalSubstance beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_90360 chebi_ph7_3 CHEBI:16390 biolink:ChemicalSubstance 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16390 GO:0051466 biolink:BiologicalProcess positive regulation of corticotropin-releasing hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell. go-plus.json up-regulation of corticotropin-releasing hormone secretion|positive regulation of CRH secretion|positive regulation of CRF secretion|upregulation of corticotropin-releasing hormone secretion|up regulation of corticotropin-releasing hormone secretion|activation of corticotropin-releasing hormone secretion|stimulation of corticotropin-releasing hormone secretion|positive regulation of corticotropin-releasing factor secretion http://purl.obolibrary.org/obo/GO_0051466 GO:0002415 biolink:BiologicalProcess immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa. go-plus.json antibody transcytosis mediated by pIgR|immunoglobulin transcytosis mediated by pIgR http://purl.obolibrary.org/obo/GO_0002415 CHEBI:90361 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_90361 GO:0002410 biolink:BiologicalProcess plasmacytoid dendritic cell chemotaxis The movement of a plasmacytoid dendritic cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0002410 GO:0051469 biolink:BiologicalProcess vesicle fusion with vacuole The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. go-plus.json heterotypic vacuole fusion (non-autophagic)|heterotypic vacuole fusion, non-autophagic http://purl.obolibrary.org/obo/GO_0051469 GO:0002411 biolink:BiologicalProcess T cell tolerance induction to tumor cell A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor. go-plus.json http://purl.obolibrary.org/obo/GO_0002411 GO:2000698 biolink:BiologicalProcess positive regulation of epithelial cell differentiation involved in kidney development Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development. go-plus.json http://purl.obolibrary.org/obo/GO_2000698 GO:2000699 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in ureteric bud formation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct. go-plus.json FGF receptor signalling pathway of ureteric bud formation|FGFR signaling pathway of ureteric bud formation|fibroblast growth factor receptor signalling pathway of ureteric bud formation|fibroblast growth factor receptor signaling pathway of ureteric bud formation|FGF receptor signaling pathway of ureteric bud formation http://purl.obolibrary.org/obo/GO_2000699 GO:1905640 biolink:BiologicalProcess response to acetaldehyde Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905640 GO:1905641 biolink:BiologicalProcess cellular response to acetaldehyde Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905641 GO:1905631 biolink:BiologicalProcess cellular response to glyceraldehyde Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1905631 GO:2000690 biolink:BiologicalProcess regulation of cardiac muscle cell myoblast differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation. go-plus.json regulation of cardiac myoblast differentiation|regulation of myocardial precursor cell differentiation http://purl.obolibrary.org/obo/GO_2000690 GO:2000691 biolink:BiologicalProcess negative regulation of cardiac muscle cell myoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. go-plus.json negative regulation of myocardial precursor cell differentiation|negative regulation of cardiac myoblast differentiation http://purl.obolibrary.org/obo/GO_2000691 GO:1905632 biolink:BiologicalProcess protein localization to euchromatin A process in which a protein is transported to, or maintained in, a location within an euchromatin. go-plus.json protein localization in euchromatin|protein localisation in euchromatin|protein localisation to euchromatin http://purl.obolibrary.org/obo/GO_1905632 GO:1905633 biolink:BiologicalProcess establishment of protein localization to euchromatin The directed movement of a protein to a specific location in an euchromatin. go-plus.json establishment of protein localization in euchromatin|establishment of protein localisation in euchromatin|establishment of protein localisation to euchromatin http://purl.obolibrary.org/obo/GO_1905633 GO:2000692 biolink:BiologicalProcess negative regulation of seed maturation Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation. go-plus.json http://purl.obolibrary.org/obo/GO_2000692 GO:2000693 biolink:BiologicalProcess positive regulation of seed maturation Any process that activates or increases the frequency, rate or extent of seed maturation. go-plus.json http://purl.obolibrary.org/obo/GO_2000693 GO:1905634 biolink:BiologicalProcess regulation of protein localization to chromatin Any process that modulates the frequency, rate or extent of protein localization to chromatin. go-plus.json regulation of protein localisation to chromatin http://purl.obolibrary.org/obo/GO_1905634 GO:1905635 biolink:BiologicalProcess FACT complex assembly The aggregation, arrangement and bonding together of a set of components to form a FACT complex. go-plus.json FACT complex formation|Facilitates chromatin transcription complex formation|Facilitates chromatin transcription complex assembly http://purl.obolibrary.org/obo/GO_1905635 GO:2000694 biolink:BiologicalProcess regulation of phragmoplast microtubule organization Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization. go-plus.json regulation of phragmoplast microtubule organisation|regulation of phragmoplast microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_2000694 GO:1905636 biolink:BiologicalProcess positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. go-plus.json upregulation of RNA polymerase II regulatory region sequence-specific DNA binding|up regulation of RNA polymerase II regulatory region sequence-specific DNA binding|activation of RNA polymerase II regulatory region sequence-specific DNA binding|up-regulation of RNA polymerase II regulatory region sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_1905636 GO:2000695 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2000695 GO:2000696 biolink:BiologicalProcess regulation of epithelial cell differentiation involved in kidney development Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. go-plus.json http://purl.obolibrary.org/obo/GO_2000696 GO:1905637 biolink:BiologicalProcess regulation of mitochondrial mRNA catabolic process Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1905637 GO:1905638 biolink:BiologicalProcess negative regulation of mitochondrial mRNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process. go-plus.json down-regulation of mitochondrial mRNA catabolic process|downregulation of mitochondrial mRNA catabolic process|down regulation of mitochondrial mRNA catabolic process|inhibition of mitochondrial mRNA catabolic process http://purl.obolibrary.org/obo/GO_1905638 GO:2000697 biolink:BiologicalProcess negative regulation of epithelial cell differentiation involved in kidney development Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development. go-plus.json http://purl.obolibrary.org/obo/GO_2000697 GO:1905639 biolink:BiologicalProcess positive regulation of mitochondrial mRNA catabolic process Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process. go-plus.json activation of mitochondrial mRNA catabolic process|up-regulation of mitochondrial mRNA catabolic process|up regulation of mitochondrial mRNA catabolic process|upregulation of mitochondrial mRNA catabolic process http://purl.obolibrary.org/obo/GO_1905639 CHEBI:16388 biolink:ChemicalSubstance 4-hydroxymandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16388 GO:0051460 biolink:BiologicalProcess negative regulation of corticotropin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. go-plus.json downregulation of adrenocorticotropin secretion|negative regulation of adrenotropin secretion|negative regulation of adrenocorticotropin secretion|down-regulation of adrenocorticotropin secretion|negative regulation of ACTH secretion|negative regulation of adrenotropic hormone secretion|inhibition of adrenocorticotropin secretion|negative regulation of adrenocorticotropic hormone secretion|negative regulation of corticotropic hormone secretion|down regulation of adrenocorticotropin secretion http://purl.obolibrary.org/obo/GO_0051460 CHEBI:16389 biolink:ChemicalSubstance ubiquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_16389 chebi_ph7_3 CHEBI:16387 biolink:ChemicalSubstance (R)-N-methylcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_16387 GO:0002416 biolink:BiologicalProcess IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals. go-plus.json IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor|IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor http://purl.obolibrary.org/obo/GO_0002416 GO:0051463 biolink:BiologicalProcess negative regulation of cortisol secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell. go-plus.json down-regulation of cortisol secretion|downregulation of cortisol secretion|down regulation of cortisol secretion|inhibition of cortisol secretion http://purl.obolibrary.org/obo/GO_0051463 CHEBI:16384 biolink:ChemicalSubstance trans-5-O-caffeoyl-D-quinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_16384 CHEBI:90362 biolink:ChemicalSubstance 2-methylhexenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_90362 GO:0051464 biolink:BiologicalProcess positive regulation of cortisol secretion Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell. go-plus.json upregulation of cortisol secretion|stimulation of cortisol secretion|activation of cortisol secretion|up-regulation of cortisol secretion|up regulation of cortisol secretion http://purl.obolibrary.org/obo/GO_0051464 GO:0002417 biolink:BiologicalProcess B cell antigen processing and presentation mediated by B cell receptor uptake of antigen B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor. go-plus.json B-cell antigen processing and presentation mediated by B cell receptor uptake of antigen|B-lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen|B lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen http://purl.obolibrary.org/obo/GO_0002417 CHEBI:16385 biolink:ChemicalSubstance organic sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16385 GO:0002418 biolink:BiologicalProcess immune response to tumor cell An immune system process that functions in the response of an organism to a tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0002418 CHEBI:16382 biolink:ChemicalSubstance iodide go-plus.json http://purl.obolibrary.org/obo/CHEBI_16382 chebi_ph7_3 GO:0051461 biolink:BiologicalProcess positive regulation of corticotropin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell. go-plus.json up regulation of adrenocorticotropin secretion|activation of adrenocorticotropin secretion|stimulation of adrenocorticotropin secretion|positive regulation of adrenotropin secretion|positive regulation of adrenocorticotropic hormone secretion|positive regulation of ACTH secretion|up-regulation of adrenocorticotropin secretion|positive regulation of adrenotropic hormone secretion|positive regulation of corticotropic hormone secretion|upregulation of adrenocorticotropin secretion|positive regulation of adrenocorticotropin secretion http://purl.obolibrary.org/obo/GO_0051461 GO:0002419 biolink:BiologicalProcess T cell mediated cytotoxicity directed against tumor cell target The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. go-plus.json T-lymphocyte mediated cytotoxicity directed against tumor cell target|T-cell mediated cytotoxicity directed against tumor cell target|T lymphocyte mediated cytotoxicity directed against tumor cell target http://purl.obolibrary.org/obo/GO_0002419 CHEBI:16383 biolink:ChemicalSubstance cis-aconitate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_16383 chebi_ph7_3 GO:0051462 biolink:BiologicalProcess regulation of cortisol secretion Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0051462 CHEBI:507499 biolink:ChemicalSubstance tricetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_507499 CHEBI:65303 biolink:ChemicalSubstance phosphatidylcholine 30:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_65303 chebi_ph7_3 CHEBI:65309 biolink:ChemicalSubstance N(omega)-methyl-L-arginine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65309 CHEBI:65305 biolink:ChemicalSubstance purine deoxyribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65305 CHEBI:65306 biolink:ChemicalSubstance pyrimidine deoxyribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65306 CHEBI:80946 biolink:ChemicalSubstance 3-octanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_80946 chebi_ph7_3 CHEBI:65311 biolink:ChemicalSubstance corticotropin-releasing hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_65311 CHEBI:65314 biolink:ChemicalSubstance pseudouridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65314 chebi_ph7_3 PR:000003761 biolink:Protein pituitary adenylate cyclase-activating polypeptide A protein that is a translation product of the human ADCYAP1 gene or a 1:1 ortholog thereof. go-plus.json PACAP|ADCYAP1 http://purl.obolibrary.org/obo/PR_000003761 CHEBI:65315 biolink:ChemicalSubstance uridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65315 chebi_ph7_3 CHEBI:65316 biolink:ChemicalSubstance L-tyrosine-O-sulfate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65316 CHEBI:65317 biolink:ChemicalSubstance 2'-deoxynucleoside 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65317 chebi_ph7_3 CHEBI:65318 biolink:ChemicalSubstance cyanophycin macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_65318 CHEBI:65322 biolink:ChemicalSubstance hemiterpenoid indole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65322 CHEBI:65323 biolink:ChemicalSubstance monoterpenoid indole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65323 CHEBI:65320 biolink:ChemicalSubstance pseudouridine 5'-phosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_65320 CHEBI:65321 biolink:ChemicalSubstance terpenoid indole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_65321 CHEBI:65327 biolink:ChemicalSubstance D-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_65327 PR:000003777 biolink:Protein adiponectin A protein that is a translation product of the human ADIPOQ gene or a 1:1 ortholog thereof. go-plus.json adipocyte complement-related 30 kDa protein|APM1|ADIPOQ|adipose most abundant gene transcript 1 protein|apM-1|gelatin-binding protein|ACRP30|ACDC|adipocyte, C1q and collagen domain-containing protein|adipocyte-specific protein AdipoQ|GBP28|30 kDa adipocyte complement-related protein http://purl.obolibrary.org/obo/PR_000003777 CHEBI:65328 biolink:ChemicalSubstance L-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_65328 GO:0002489 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway|TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway|endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent http://purl.obolibrary.org/obo/GO_0002489 GO:0002485 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules. go-plus.json endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent|TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway|TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway http://purl.obolibrary.org/obo/GO_0002485 GO:0002486 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules. go-plus.json TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway|endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent|TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway http://purl.obolibrary.org/obo/GO_0002486 GO:0002487 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules. go-plus.json endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway http://purl.obolibrary.org/obo/GO_0002487 GO:0002488 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway http://purl.obolibrary.org/obo/GO_0002488 GO:0002481 biolink:BiologicalProcess antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib|TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent http://purl.obolibrary.org/obo/GO_0002481 CHEBI:80963 biolink:ChemicalSubstance 3-(2'-Methylthio)ethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80963 GO:0002482 biolink:BiologicalProcess antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent http://purl.obolibrary.org/obo/GO_0002482 CHEBI:80964 biolink:ChemicalSubstance 3-(3'-Methylthio)propylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_80964 CHEBI:65335 biolink:ChemicalSubstance 3-deoxy-D-manno-octulosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_65335 GO:0002483 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. go-plus.json endogenous peptide antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002483 GO:0002484 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules. go-plus.json endogenous peptide antigen processing and presentation via MHC class I via ER pathway http://purl.obolibrary.org/obo/GO_0002484 CHEBI:65331 biolink:ChemicalSubstance alkyl caffeate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_65331 chebi_ph7_3 GO:0002480 biolink:BiologicalProcess antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules. go-plus.json TAP-independent exogenous peptide antigen processing and presentation via MHC class I|cross presentation|exogenous peptide antigen processing and presentation via MHC class I, TAP-independent|cross-presentation|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_0002480 GO:0002496 biolink:BiologicalProcess proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002496 GO:0002497 biolink:BiologicalProcess proteasomal proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation. go-plus.json http://purl.obolibrary.org/obo/GO_0002497 GO:0002498 biolink:BiologicalProcess proteolysis within endoplasmic reticulum associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation. go-plus.json proteolysis within ER associated with antigen processing and presentation|endoplasmic reticulum proteolysis associated with antigen processing and presentation|ER proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002498 GO:0002499 biolink:BiologicalProcess proteolysis within endosome associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation. go-plus.json endosomal proteolysis associated with antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002499 GO:0002492 biolink:BiologicalProcess peptide antigen assembly with MHC class Ib protein complex The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json http://purl.obolibrary.org/obo/GO_0002492 GO:0002493 biolink:BiologicalProcess lipid antigen assembly with MHC class Ib protein complex The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family. go-plus.json http://purl.obolibrary.org/obo/GO_0002493 GO:0002494 biolink:BiologicalProcess lipid antigen transport The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0002494 GO:0002495 biolink:BiologicalProcess antigen processing and presentation of peptide antigen via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. go-plus.json peptide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002495 CHEBI:65340 biolink:ChemicalSubstance 5-formyltetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65340 chebi_ph7_3 CHEBI:65341 biolink:ChemicalSubstance 5-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65341 chebi_ph7_3 GO:0002490 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. go-plus.json endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent|TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway|TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway http://purl.obolibrary.org/obo/GO_0002490 CHEBI:65342 biolink:ChemicalSubstance 5-oxo-ETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_65342 chebi_ph7_3 GO:0002491 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. go-plus.json endogenous peptide antigen processing and presentation via MHC class II http://purl.obolibrary.org/obo/GO_0002491 CHEBI:79985 biolink:ChemicalSubstance flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] go-plus.json http://purl.obolibrary.org/obo/CHEBI_79985 chebi_ph7_3 GO:0021780 biolink:BiologicalProcess glial cell fate specification The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0021780 GO:0031108 biolink:BiologicalProcess holo-[acyl-carrier-protein] biosynthetic process The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]. go-plus.json holo-[acyl-carrier-protein] anabolism|holo-[acyl-carrier-protein] synthesis|holo-[acyl-carrier-protein] formation|holo-[acyl-carrier-protein] biosynthesis|holo-[acyl-carrier protein] biosynthesis http://purl.obolibrary.org/obo/GO_0031108 GO:0021781 biolink:BiologicalProcess glial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0021781 GO:0021782 biolink:BiologicalProcess glial cell development The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0021782 GO:0031109 biolink:BiologicalProcess microtubule polymerization or depolymerization Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0031109 GO:0031106 biolink:BiologicalProcess septin ring organization Control of the formation, spatial distribution, and breakdown of the septin ring. go-plus.json septin ring organisation http://purl.obolibrary.org/obo/GO_0031106 GO:0021783 biolink:BiologicalProcess preganglionic parasympathetic fiber development The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. go-plus.json http://purl.obolibrary.org/obo/GO_0021783 GO:0031107 biolink:BiologicalProcess septin ring disassembly The controlled breakdown of a septin ring. go-plus.json http://purl.obolibrary.org/obo/GO_0031107 GO:0021784 biolink:BiologicalProcess postganglionic parasympathetic fiber development The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. go-plus.json http://purl.obolibrary.org/obo/GO_0021784 GO:0006148 biolink:BiologicalProcess inosine catabolic process The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. go-plus.json inosine breakdown|inosine catabolism|inosine degradation http://purl.obolibrary.org/obo/GO_0006148 GO:0021785 biolink:BiologicalProcess branchiomotor neuron axon guidance The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json special visceral motor neuron axon guidance|branchial motor axon guidance|BMN axon guidance http://purl.obolibrary.org/obo/GO_0021785 GO:0031104 biolink:BiologicalProcess dendrite regeneration The regrowth of dendrites in response to their loss or damage. go-plus.json http://purl.obolibrary.org/obo/GO_0031104 GO:0031105 biolink:CellularComponent septin complex A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric. go-plus.json http://purl.obolibrary.org/obo/GO_0031105 goslim_pir GO:0021786 biolink:BiologicalProcess branchiomotor neuron axon guidance in neural tube The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json http://purl.obolibrary.org/obo/GO_0021786 GO:0006149 biolink:BiologicalProcess deoxyinosine catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside. go-plus.json deoxyinosine degradation|deoxyinosine breakdown|deoxyinosine catabolism http://purl.obolibrary.org/obo/GO_0006149 GO:0006146 biolink:BiologicalProcess adenine catabolic process The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine. go-plus.json adenine catabolism|adenine degradation|adenine breakdown http://purl.obolibrary.org/obo/GO_0006146 GO:0045754 biolink:BiologicalProcess positive regulation of acetate catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json stimulation of acetate catabolic process|up-regulation of acetate catabolic process|upregulation of acetate catabolic process|positive regulation of acetate degradation|positive regulation of acetate breakdown|positive regulation of acetate catabolism|up regulation of acetate catabolic process|activation of acetate catabolic process http://purl.obolibrary.org/obo/GO_0045754 PR:000007495 biolink:Protein fibroblast growth factor 4 A protein that is a translation product of the human FGF4 gene or a 1:1 ortholog thereof. go-plus.json heparin secretory-transforming protein 1|K-fibroblast growth factor|KS3|transforming protein KS3|HSTF-1|HBGF-4|HST|heparin-binding growth factor 4|Kfgf|FGF4|HSTF1|HST-1|FGF-4 http://purl.obolibrary.org/obo/PR_000007495 PR:000007496 biolink:Protein fibroblast growth factor 5 A protein that is a translation product of the human FGF5 gene or a 1:1 ortholog thereof. go-plus.json Smag-82|HBGF-5|heparin-binding growth factor 5|FGF5|FGF-5 http://purl.obolibrary.org/obo/PR_000007496 GO:0045755 biolink:BiologicalProcess negative regulation of initiation of acetate catabolic process by acetate Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json down-regulation of initiation of acetate catabolic process by acetate|negative regulation of initiation of acetate breakdown by acetate|negative regulation of initiation of acetate degradation by acetate|downregulation of initiation of acetate catabolic process by acetate|down regulation of initiation of acetate catabolic process by acetate|inhibition of initiation of acetate catabolic process by acetate http://purl.obolibrary.org/obo/GO_0045755 GO:0006147 biolink:BiologicalProcess guanine catabolic process The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. go-plus.json guanine degradation|guanine catabolism|guanine breakdown http://purl.obolibrary.org/obo/GO_0006147 PR:000007497 biolink:Protein fibroblast growth factor 6 A protein that is a translation product of the human FGF6 gene or a 1:1 ortholog thereof. go-plus.json heparin secretory-transforming protein 2|HST2|HBGF-6|HSTF-2|heparin-binding growth factor 6|FGF6|HSTF2|FGF-6|HST-2 http://purl.obolibrary.org/obo/PR_000007497 GO:0006144 biolink:BiologicalProcess purine nucleobase metabolic process The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. go-plus.json purine base metabolism|purine base metabolic process|purine metabolic process|purine metabolism http://purl.obolibrary.org/obo/GO_0006144 GO:0045752 biolink:BiologicalProcess positive regulation of Toll signaling pathway Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway. go-plus.json up regulation of Toll signaling pathway|positive regulation of Tl signalling pathway|positive regulation of Tl signaling pathway|upregulation of Toll signaling pathway|stimulation of Toll signaling pathway|up-regulation of Toll signaling pathway|activation of Toll signaling pathway http://purl.obolibrary.org/obo/GO_0045752 GO:0006145 biolink:BiologicalProcess purine nucleobase catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. go-plus.json purine base catabolic process|purine base catabolism|purine base degradation|purine base breakdown http://purl.obolibrary.org/obo/GO_0006145 GO:0045753 biolink:BiologicalProcess negative regulation of acetate catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json down-regulation of acetate catabolic process|inhibition of acetate catabolic process|down regulation of acetate catabolic process|negative regulation of acetate catabolism|negative regulation of acetate degradation|downregulation of acetate catabolic process|negative regulation of acetate breakdown http://purl.obolibrary.org/obo/GO_0045753 GO:0045750 biolink:BiologicalProcess obsolete positive regulation of S phase of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity. go-plus.json positive regulation of S-phase of mitotic cell cycle|upregulation of S phase of mitotic cell cycle|up regulation of S phase of mitotic cell cycle|positive regulation of S phase of mitotic cell cycle|activation of S phase of mitotic cell cycle|stimulation of S phase of mitotic cell cycle|up-regulation of S phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045750 GO:0006142 biolink:BiologicalProcess regulation of pyrimidine nucleobase metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases. go-plus.json regulation of pyrimidine base metabolic process|regulation of pyrimidine base metabolism http://purl.obolibrary.org/obo/GO_0006142 GO:0006143 biolink:BiologicalProcess obsolete purine metabolic process OBSOLETE. (Was not defined before being made obsolete). go-plus.json purine metabolic process http://purl.obolibrary.org/obo/GO_0006143 GO:0045751 biolink:BiologicalProcess negative regulation of Toll signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway. go-plus.json down-regulation of Toll signaling pathway|negative regulation of Tl signaling pathway|downregulation of Toll signaling pathway|negative regulation of Tl signalling pathway|down regulation of Toll signaling pathway|inhibition of Toll signaling pathway http://purl.obolibrary.org/obo/GO_0045751 GO:0070709 biolink:BiologicalProcess RNA guanosine insertion The modification of an RNA molecule by insertion of a guanosine nucleotide. go-plus.json RNA G insertion http://purl.obolibrary.org/obo/GO_0070709 GO:0006140 biolink:BiologicalProcess regulation of nucleotide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. go-plus.json regulation of nucleotide metabolism http://purl.obolibrary.org/obo/GO_0006140 PR:000007494 biolink:Protein fibroblast growth factor 3 A protein that is a translation product of the human FGF3 gene or a 1:1 ortholog thereof. go-plus.json HBGF-3|INT2|heparin-binding growth factor 3|proto-oncogene Int-2|INT-2 proto-oncogene protein|Int-2|FGF3|FGF-3 http://purl.obolibrary.org/obo/PR_000007494 GO:0006141 biolink:BiologicalProcess regulation of purine nucleobase metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines. go-plus.json regulation of purine base metabolic process|regulation of purine base metabolism http://purl.obolibrary.org/obo/GO_0006141 GO:0070718 biolink:CellularComponent alphaPDGFR-SHP-2 complex A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway. go-plus.json PDGFRA-SHP-2 complex, PDGF stimulated http://purl.obolibrary.org/obo/GO_0070718 GO:0006150 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006150 GO:0070719 biolink:CellularComponent alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway. go-plus.json PDGFRA-PLC-gamma-1-PI3K-SHP-2 complex, PDGF stimulated http://purl.obolibrary.org/obo/GO_0070719 GO:0070716 biolink:BiologicalProcess mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication. go-plus.json mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication http://purl.obolibrary.org/obo/GO_0070716 GO:0070717 biolink:MolecularActivity poly-purine tract binding Binding to a stretch of purines (adenine or guanine) in an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070717 GO:0070714 biolink:BiologicalProcess RNA guanosine-uridine insertion The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide. go-plus.json RNA GU insertion http://purl.obolibrary.org/obo/GO_0070714 GO:0045758 biolink:BiologicalProcess obsolete positive regulation of actin polymerization and/or depolymerization OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization and/or depolymerization. go-plus.json positive regulation of actin polymerization and/or depolymerization http://purl.obolibrary.org/obo/GO_0045758 GO:0045759 biolink:BiologicalProcess negative regulation of action potential Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json down regulation of action potential|inhibition of action potential|down-regulation of action potential|downregulation of action potential http://purl.obolibrary.org/obo/GO_0045759 GO:0070715 biolink:BiologicalProcess sodium-dependent organic cation transport The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0070715 GO:0045756 biolink:BiologicalProcess positive regulation of initiation of acetate catabolic process by acetate Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json activation of initiation of acetate catabolic process by acetate|up-regulation of initiation of acetate catabolic process by acetate|up regulation of initiation of acetate catabolic process by acetate|positive regulation of initiation of acetate breakdown by acetate|positive regulation of initiation of acetate degradation by acetate|upregulation of initiation of acetate catabolic process by acetate|stimulation of initiation of acetate catabolic process by acetate http://purl.obolibrary.org/obo/GO_0045756 GO:0070712 biolink:BiologicalProcess RNA cytidine-uridine insertion The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide. go-plus.json RNA CU insertion http://purl.obolibrary.org/obo/GO_0070712 GO:0070713 biolink:BiologicalProcess RNA guanosine-cytidine insertion The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide. go-plus.json RNA GC insertion http://purl.obolibrary.org/obo/GO_0070713 GO:0045757 biolink:BiologicalProcess obsolete negative regulation of actin polymerization and/or depolymerization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization and/or depolymerization. go-plus.json negative regulation of actin polymerization and/or depolymerization http://purl.obolibrary.org/obo/GO_0045757 GO:0070710 biolink:BiologicalProcess RNA uridine deletion The modification of an RNA molecule by removal of a uridine nucleotide. go-plus.json RNA uridine excision|RNA U deletion http://purl.obolibrary.org/obo/GO_0070710 GO:0021787 biolink:BiologicalProcess chemorepulsion of branchiomotor neuron axon in neural tube The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json negative chemotaxis of branchiomotor neuron axon in neural tube http://purl.obolibrary.org/obo/GO_0021787 GO:0031102 biolink:BiologicalProcess neuron projection regeneration The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage. go-plus.json neurite regeneration http://purl.obolibrary.org/obo/GO_0031102 GO:0070711 biolink:BiologicalProcess RNA adenosine-uridine insertion The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide. go-plus.json RNA AU insertion http://purl.obolibrary.org/obo/GO_0070711 GO:0021788 biolink:BiologicalProcess chemoattraction of branchiomotor neuron axon in neural tube The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json positive chemotaxis of branchiomotor neuron axon in neural tube http://purl.obolibrary.org/obo/GO_0021788 GO:0031103 biolink:BiologicalProcess axon regeneration The regrowth of axons following their loss or damage. go-plus.json http://purl.obolibrary.org/obo/GO_0031103 GO:0021789 biolink:BiologicalProcess branchiomotor neuron axon guidance in branchial arch mesenchyme The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json http://purl.obolibrary.org/obo/GO_0021789 GO:0031100 biolink:BiologicalProcess animal organ regeneration The regrowth of a lost or destroyed animal organ. go-plus.json http://purl.obolibrary.org/obo/GO_0031100 GO:0031101 biolink:BiologicalProcess fin regeneration The regrowth of fin tissue following its loss or destruction. go-plus.json http://purl.obolibrary.org/obo/GO_0031101 GO:0021770 biolink:BiologicalProcess parahippocampal gyrus development The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex. Wikipedia:parahippocampal_gyrus go-plus.json hippocampal gyrus development http://purl.obolibrary.org/obo/GO_0021770 GO:0021771 biolink:BiologicalProcess lateral geniculate nucleus development The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina. go-plus.json LGN development http://purl.obolibrary.org/obo/GO_0021771 GO:0021772 biolink:BiologicalProcess olfactory bulb development The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021772 GO:0021773 biolink:BiologicalProcess striatal medium spiny neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum. go-plus.json striatal MSN differentiation|medium-sized spiny neuron differentiation http://purl.obolibrary.org/obo/GO_0021773 GO:0021774 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate. go-plus.json retinoic acid receptor signalling pathway involved in ventral spinal cord interneuron specification http://purl.obolibrary.org/obo/GO_0021774 GO:0006159 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006159 GO:0021775 biolink:BiologicalProcess smoothened signaling pathway involved in ventral spinal cord interneuron specification The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate. go-plus.json hh signaling pathway involved in ventral spinal cord interneuron specification|hedgehog signaling pathway involved in ventral spinal cord interneuron specification|smoothened signalling pathway involved in ventral spinal cord interneuron specification http://purl.obolibrary.org/obo/GO_0021775 GO:0045765 biolink:BiologicalProcess regulation of angiogenesis Any process that modulates the frequency, rate or extent of angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0045765 GO:0006157 biolink:BiologicalProcess deoxyadenosine catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. go-plus.json deoxyadenosine degradation|deoxyadenosine breakdown|deoxyadenosine phosphorolysis|deoxyadenosine catabolism http://purl.obolibrary.org/obo/GO_0006157 GO:0045766 biolink:BiologicalProcess positive regulation of angiogenesis Any process that activates or increases angiogenesis. go-plus.json stimulation of angiogenesis|activation of angiogenesis|up-regulation of angiogenesis|up regulation of angiogenesis|upregulation of angiogenesis http://purl.obolibrary.org/obo/GO_0045766 GO:0006158 biolink:BiologicalProcess obsolete deoxyadenosine deaminase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json deoxyadenosine deaminase reaction http://purl.obolibrary.org/obo/GO_0006158 GO:0045763 biolink:BiologicalProcess negative regulation of cellular amino acid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. go-plus.json inhibition of amino acid metabolic process|negative regulation of amino acid metabolism|down-regulation of amino acid metabolic process|downregulation of amino acid metabolic process|down regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0045763 GO:0006155 biolink:BiologicalProcess obsolete adenosine deaminase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json adenosine deaminase reaction http://purl.obolibrary.org/obo/GO_0006155 GO:0045764 biolink:BiologicalProcess positive regulation of cellular amino acid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. go-plus.json upregulation of amino acid metabolic process|positive regulation of amino acid metabolism|stimulation of amino acid metabolic process|activation of amino acid metabolic process|up-regulation of amino acid metabolic process|up regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0045764 GO:0006156 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006156 GO:0045761 biolink:BiologicalProcess regulation of adenylate cyclase activity Any process that modulates the frequency, rate or extent of adenylate cyclase activity. go-plus.json adenylate cyclase regulator|regulation of adenylyl cyclase activity http://purl.obolibrary.org/obo/GO_0045761 GO:0006153 biolink:BiologicalProcess obsolete purine nucleosidase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json purine nucleosidase reaction http://purl.obolibrary.org/obo/GO_0006153 GO:0045762 biolink:BiologicalProcess positive regulation of adenylate cyclase activity Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity. go-plus.json stimulation of adenylate cyclase activity|positive regulation of adenylyl cyclase activity|up-regulation of adenylate cyclase activity|up regulation of adenylate cyclase activity|adenylate cyclase activator|upregulation of adenylate cyclase activity http://purl.obolibrary.org/obo/GO_0045762 GO:0006154 biolink:BiologicalProcess adenosine catabolic process The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. go-plus.json adenosine phosphorolysis|adenosine catabolism|adenosine degradation|adenosine breakdown http://purl.obolibrary.org/obo/GO_0006154 GO:0006151 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006151 GO:0045760 biolink:BiologicalProcess positive regulation of action potential Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json up regulation of action potential|upregulation of action potential|stimulation of action potential|up-regulation of action potential|activation of action potential http://purl.obolibrary.org/obo/GO_0045760 GO:0006152 biolink:BiologicalProcess purine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json purine nucleoside degradation|purine nucleoside breakdown|purine nucleoside catabolism http://purl.obolibrary.org/obo/GO_0006152 GO:0070707 biolink:BiologicalProcess RNA dinucleotide insertion The modification of an RNA molecule by insertion of a dinucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0070707 GO:0006160 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006160 GO:0070708 biolink:BiologicalProcess RNA cytidine insertion The modification of an RNA molecule by insertion of a cytidine nucleotide. go-plus.json RNA C insertion http://purl.obolibrary.org/obo/GO_0070708 GO:0006161 biolink:BiologicalProcess deoxyguanosine catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose. go-plus.json deoxyguanosine breakdown|deoxyguanosine catabolism|deoxyguanosine degradation http://purl.obolibrary.org/obo/GO_0006161 GO:0070705 biolink:BiologicalProcess RNA nucleotide insertion The modification of an RNA molecule by insertion of one or more nucleotides. go-plus.json http://purl.obolibrary.org/obo/GO_0070705 GO:0070706 biolink:BiologicalProcess RNA nucleotide deletion The modification of an RNA molecule by removal of a single nucleotide. go-plus.json RNA nucleotide excision http://purl.obolibrary.org/obo/GO_0070706 GO:0045769 biolink:BiologicalProcess negative regulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. go-plus.json down regulation of asymmetric cell division|inhibition of asymmetric cell division|down-regulation of asymmetric cell division|downregulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0045769 GO:0070703 biolink:CellularComponent outer mucus layer The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0070703 GO:0070704 biolink:MolecularActivity sterol desaturase activity Catalysis of the introduction of a double bond into a sterol molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070704 GO:0045767 biolink:BiologicalProcess obsolete regulation of anti-apoptosis OBSOLETE. Any process that modulates the frequency, rate or extent of anti-apoptosis. go-plus.json regulation of anti-apoptosis http://purl.obolibrary.org/obo/GO_0045767 GO:0070701 biolink:CellularComponent mucus layer An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. go-plus.json mucus|mucous|extracellular proteinaceous gel|mucous layer http://purl.obolibrary.org/obo/GO_0070701 GO:0070702 biolink:CellularComponent inner mucus layer The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0070702 GO:0045768 biolink:BiologicalProcess obsolete positive regulation of anti-apoptosis OBSOLETE. Any process that activates or increases the frequency, rate or extent of anti-apoptosis. go-plus.json stimulation of anti-apoptosis|activation of anti-apoptosis|up-regulation of anti-apoptosis|positive regulation of anti-apoptosis|up regulation of anti-apoptosis|upregulation of anti-apoptosis http://purl.obolibrary.org/obo/GO_0045768 GO:0021776 biolink:BiologicalProcess smoothened signaling pathway involved in spinal cord motor neuron cell fate specification The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway. go-plus.json hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification|hh signaling pathway involved in spinal cord motor neuron cell fate specification|smoothened signalling pathway involved in spinal cord motor neuron cell fate specification http://purl.obolibrary.org/obo/GO_0021776 GO:0070700 biolink:MolecularActivity BMP receptor binding Binding to a BMP receptor. go-plus.json bone morphogenetic protein receptor binding http://purl.obolibrary.org/obo/GO_0070700 GO:0021777 biolink:BiologicalProcess obsolete BMP signaling pathway involved in spinal cord association neuron specification OBSOLETE. A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate. go-plus.json BMP signalling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification http://purl.obolibrary.org/obo/GO_0021777 GO:0021778 biolink:BiologicalProcess oligodendrocyte cell fate specification The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0021778 GO:0021779 biolink:BiologicalProcess oligodendrocyte cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0021779 GO:0006128 biolink:BiologicalProcess obsolete oxidized glutathione reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json oxidized glutathione reduction http://purl.obolibrary.org/obo/GO_0006128 GO:0021761 biolink:BiologicalProcess limbic system development The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. go-plus.json http://purl.obolibrary.org/obo/GO_0021761 GO:0021762 biolink:BiologicalProcess substantia nigra development The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). go-plus.json http://purl.obolibrary.org/obo/GO_0021762 GO:0006129 biolink:BiologicalProcess obsolete protein-disulfide reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json protein-disulfide reduction|protein-disulphide reduction http://purl.obolibrary.org/obo/GO_0006129 GO:0006126 biolink:BiologicalProcess obsolete other pathways of electron transport OBSOLETE. (Was not defined before being made obsolete). go-plus.json other pathways of electron transport http://purl.obolibrary.org/obo/GO_0006126 GO:0021763 biolink:BiologicalProcess subthalamic nucleus development The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function. go-plus.json corpus luysi development http://purl.obolibrary.org/obo/GO_0021763 GO:0021764 biolink:BiologicalProcess amygdala development The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. go-plus.json http://purl.obolibrary.org/obo/GO_0021764 GO:0006127 biolink:BiologicalProcess glycerophosphate shuttle The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle. MetaCyc:PWY-6118 go-plus.json http://purl.obolibrary.org/obo/GO_0006127 GO:0045776 biolink:BiologicalProcess negative regulation of blood pressure Any process in which the force of blood traveling through the circulatory system is decreased. go-plus.json downregulation of blood pressure|down regulation of blood pressure|inhibition of blood pressure|down-regulation of blood pressure http://purl.obolibrary.org/obo/GO_0045776 GO:0006124 biolink:BiologicalProcess ferredoxin metabolic process The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each. go-plus.json ferredoxin metabolism http://purl.obolibrary.org/obo/GO_0006124 GO:0006125 biolink:BiologicalProcess obsolete thioredoxin pathway OBSOLETE. This term was not defined before being made obsolete. MetaCyc:THIOREDOX-PWY go-plus.json thioredoxin reduction|thioredoxin pathway http://purl.obolibrary.org/obo/GO_0006125 GO:0045777 biolink:BiologicalProcess positive regulation of blood pressure Any process in which the force of blood traveling through the circulatory system is increased. go-plus.json upregulation of blood pressure|stimulation of blood pressure|up-regulation of blood pressure|activation of blood pressure|up regulation of blood pressure http://purl.obolibrary.org/obo/GO_0045777 GO:0045774 biolink:BiologicalProcess negative regulation of beta 2 integrin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins. go-plus.json negative regulation of beta 2 integrin anabolism|downregulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin synthesis|down regulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin formation|inhibition of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin biosynthesis|down-regulation of beta 2 integrin biosynthetic process http://purl.obolibrary.org/obo/GO_0045774 GO:0006122 biolink:BiologicalProcess mitochondrial electron transport, ubiquinol to cytochrome c The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. go-plus.json complex III (ubiquinone to cytochrome c) http://purl.obolibrary.org/obo/GO_0006122 GO:0045775 biolink:BiologicalProcess positive regulation of beta 2 integrin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins. go-plus.json up regulation of beta 2 integrin biosynthetic process|positive regulation of beta 2 integrin synthesis|positive regulation of beta 2 integrin formation|upregulation of beta 2 integrin biosynthetic process|stimulation of beta 2 integrin biosynthetic process|up-regulation of beta 2 integrin biosynthetic process|activation of beta 2 integrin biosynthetic process|positive regulation of beta 2 integrin biosynthesis|positive regulation of beta 2 integrin anabolism http://purl.obolibrary.org/obo/GO_0045775 GO:0006123 biolink:BiologicalProcess mitochondrial electron transport, cytochrome c to oxygen The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV. go-plus.json complex IV (reduction of O2) http://purl.obolibrary.org/obo/GO_0006123 GO:0045772 biolink:BiologicalProcess positive regulation of autophagosome size Any process that increases autophagosome size. go-plus.json positive regulation of autophagic vacuole size|up regulation of autophagic vacuole size|activation of autophagic vacuole size|stimulation of autophagic vacuole size|up-regulation of autophagic vacuole size|upregulation of autophagic vacuole size http://purl.obolibrary.org/obo/GO_0045772 GO:0006120 biolink:BiologicalProcess mitochondrial electron transport, NADH to ubiquinone The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation. go-plus.json complex I (NADH to ubiquinone)|oxidative phosphorylation, NADH to ubiquinone http://purl.obolibrary.org/obo/GO_0006120 GO:0006121 biolink:BiologicalProcess mitochondrial electron transport, succinate to ubiquinone The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II. go-plus.json mitochondrial electron transport, succinate to coenzyme Q|oxidative phosphorylation, succinate to ubiquinone|complex II (succinate to ubiquinone) http://purl.obolibrary.org/obo/GO_0006121 GO:0045773 biolink:BiologicalProcess positive regulation of axon extension Any process that activates or increases the frequency, rate or extent of axon extension. go-plus.json stimulation of axon extension|up-regulation of axon extension|activation of axon extension|up regulation of axon extension|upregulation of axon extension http://purl.obolibrary.org/obo/GO_0045773 GO:0045770 biolink:BiologicalProcess positive regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. go-plus.json up regulation of asymmetric cell division|upregulation of asymmetric cell division|stimulation of asymmetric cell division|up-regulation of asymmetric cell division|activation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0045770 GO:0045771 biolink:BiologicalProcess negative regulation of autophagosome size Any process that reduces autophagosome size. go-plus.json down regulation of autophagic vacuole size|downregulation of autophagic vacuole size|negative regulation of autophagic vacuole size|down-regulation of autophagic vacuole size|inhibition of autophagic vacuole size http://purl.obolibrary.org/obo/GO_0045771 GO:0070738 biolink:MolecularActivity tubulin-glycine ligase activity Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin. go-plus.json tubulin glycylase activity http://purl.obolibrary.org/obo/GO_0070738 GO:0070739 biolink:MolecularActivity protein-glutamic acid ligase activity Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein. go-plus.json protein-glutamate ligase activity|protein glutamylase activity http://purl.obolibrary.org/obo/GO_0070739 GO:0070736 biolink:MolecularActivity protein-glycine ligase activity, initiating Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein. go-plus.json protein glycylase activity, initiating http://purl.obolibrary.org/obo/GO_0070736 GO:0070737 biolink:MolecularActivity protein-glycine ligase activity, elongating Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain. go-plus.json protein glycylase activity, elongating http://purl.obolibrary.org/obo/GO_0070737 GO:0070734 biolink:BiologicalProcess histone H3-K27 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone. go-plus.json histone H3 K27 methylation|histone H3K27me|histone lysine H3 K27 methylation http://purl.obolibrary.org/obo/GO_0070734 GO:0045778 biolink:BiologicalProcess positive regulation of ossification Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. go-plus.json upregulation of ossification|stimulation of ossification|activation of ossification|up-regulation of ossification|positive regulation of bone formation|positive regulation of bone biosynthesis|up regulation of ossification http://purl.obolibrary.org/obo/GO_0045778 GO:0070735 biolink:MolecularActivity protein-glycine ligase activity Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein. Reactome:R-HSA-8867370 go-plus.json protein glycylase activity http://purl.obolibrary.org/obo/GO_0070735 GO:0045779 biolink:BiologicalProcess negative regulation of bone resorption Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption. go-plus.json down-regulation of bone resorption|inhibition of bone resorption|down regulation of bone resorption|downregulation of bone resorption http://purl.obolibrary.org/obo/GO_0045779 GO:0070732 biolink:CellularComponent spindle envelope An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0070732 goslim_candida GO:0021765 biolink:BiologicalProcess cingulate gyrus development The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum. go-plus.json http://purl.obolibrary.org/obo/GO_0021765 GO:0070733 biolink:MolecularActivity protein adenylyltransferase activity Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins. EC:2.7.7.n1 go-plus.json AMPylator|adenosine monophosphate-protein transferase activity http://purl.obolibrary.org/obo/GO_0070733 GO:0021766 biolink:BiologicalProcess hippocampus development The progression of the hippocampus over time from its initial formation until its mature state. go-plus.json hippocampal formation development http://purl.obolibrary.org/obo/GO_0021766 GO:0070730 biolink:BiologicalProcess cAMP transport The directed movement of cyclic AMP (cAMP), into, out of or within a cell. go-plus.json cyclic AMP transport http://purl.obolibrary.org/obo/GO_0070730 GO:0021767 biolink:BiologicalProcess mammillary body development The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei. go-plus.json http://purl.obolibrary.org/obo/GO_0021767 GO:0070731 biolink:BiologicalProcess cGMP transport The directed movement of cyclic GMP (cGMP), into, out of or within a cell. go-plus.json cyclic GMP transport http://purl.obolibrary.org/obo/GO_0070731 GO:0021768 biolink:BiologicalProcess nucleus accumbens development The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. go-plus.json ventral striatum development|accumbens nucleus development http://purl.obolibrary.org/obo/GO_0021768 GO:0021769 biolink:BiologicalProcess orbitofrontal cortex development The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe. go-plus.json http://purl.obolibrary.org/obo/GO_0021769 GO:0045780 biolink:BiologicalProcess positive regulation of bone resorption Any process that activates or increases the frequency, rate or extent of bone resorption. go-plus.json up regulation of bone resorption|activation of bone resorption|stimulation of bone resorption|up-regulation of bone resorption|upregulation of bone resorption http://purl.obolibrary.org/obo/GO_0045780 GO:0055106 biolink:MolecularActivity ubiquitin-protein transferase regulator activity Binds to and modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein. go-plus.json http://purl.obolibrary.org/obo/GO_0055106 GO:0006139 biolink:BiologicalProcess nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. go-plus.json nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|nucleobase, nucleoside and nucleotide metabolic process|nucleobase, nucleoside, nucleotide and nucleic acid metabolism|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0006139 goslim_plant|goslim_pir GO:0021750 biolink:BiologicalProcess vestibular nucleus development The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021750 GO:0055107 biolink:BiologicalProcess Golgi to secretory granule transport The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex. go-plus.json http://purl.obolibrary.org/obo/GO_0055107 GO:0021751 biolink:BiologicalProcess salivary nucleus development The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021751 GO:0055108 biolink:BiologicalProcess Golgi to transport vesicle transport The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0055108 GO:0006137 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006137 GO:0021752 biolink:BiologicalProcess inferior salivary nucleus development The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021752 GO:0006138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006138 GO:0055109 biolink:BiologicalProcess invagination involved in gastrulation with mouth forming second The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0055109 GO:0021753 biolink:BiologicalProcess superior salivary nucleus development The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021753 GO:0045787 biolink:BiologicalProcess positive regulation of cell cycle Any process that activates or increases the rate or extent of progression through the cell cycle. go-plus.json stimulation of progression through cell cycle|up-regulation of progression through cell cycle|positive regulation of progression through cell cycle|activation of progression through cell cycle|up regulation of progression through cell cycle|positive regulation of cell cycle progression|upregulation of progression through cell cycle http://purl.obolibrary.org/obo/GO_0045787 GO:0006135 biolink:BiologicalProcess obsolete dihydropteridine reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json dihydropteridine reduction http://purl.obolibrary.org/obo/GO_0006135 GO:0006136 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006136 GO:0045788 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045788 GO:0045785 biolink:BiologicalProcess positive regulation of cell adhesion Any process that activates or increases the frequency, rate or extent of cell adhesion. go-plus.json up-regulation of cell adhesion|upregulation of cell adhesion|up regulation of cell adhesion|activation of cell adhesion|stimulation of cell adhesion http://purl.obolibrary.org/obo/GO_0045785 GO:0006133 biolink:BiologicalProcess obsolete 5,10-methylenetetrahydrofolate oxidation OBSOLETE. This term was not defined before being made obsolete. go-plus.json 5,10-methylenetetrahydrofolate oxidation http://purl.obolibrary.org/obo/GO_0006133 GO:0006134 biolink:BiologicalProcess obsolete dihydrobiopterin reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json dihydrobiopterin reduction http://purl.obolibrary.org/obo/GO_0006134 GO:0045786 biolink:BiologicalProcess negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. go-plus.json down-regulation of progression through cell cycle|negative regulation of progression through cell cycle|negative regulation of cell cycle progression|downregulation of progression through cell cycle|down regulation of progression through cell cycle|inhibition of progression through cell cycle http://purl.obolibrary.org/obo/GO_0045786 GO:0045783 biolink:BiologicalProcess obsolete negative regulation of calcium in ER OBSOLETE. Any process that reduces the concentration of calcium in the ER. go-plus.json negative regulation of calcium in ER http://purl.obolibrary.org/obo/GO_0045783 GO:0006131 biolink:BiologicalProcess obsolete dihydrolipoamide reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json dihydrolipoamide reduction http://purl.obolibrary.org/obo/GO_0006131 GO:0045784 biolink:BiologicalProcess obsolete positive regulation of calcium in ER OBSOLETE. Any process that increases the concentration of calcium in the ER. go-plus.json positive regulation of calcium in ER http://purl.obolibrary.org/obo/GO_0045784 GO:0006132 biolink:BiologicalProcess obsolete dihydrolipoylprotein reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json dihydrolipoylprotein reduction http://purl.obolibrary.org/obo/GO_0006132 GO:0045781 biolink:BiologicalProcess negative regulation of cell budding Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding. go-plus.json downregulation of cell budding|negative regulation of budding|down regulation of cell budding|inhibition of cell budding|down-regulation of cell budding http://purl.obolibrary.org/obo/GO_0045781 GO:0045782 biolink:BiologicalProcess positive regulation of cell budding Any process that activates or increases the frequency, rate or extent of cell budding. go-plus.json positive regulation of budding|up regulation of cell budding|upregulation of cell budding|stimulation of cell budding|up-regulation of cell budding|activation of cell budding http://purl.obolibrary.org/obo/GO_0045782 GO:0006130 biolink:BiologicalProcess obsolete 6-phosphofructokinase reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json 6-phosphofructokinase reduction http://purl.obolibrary.org/obo/GO_0006130 GO:0070729 biolink:BiologicalProcess cyclic nucleotide transport The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0070729 GO:0070727 biolink:BiologicalProcess cellular macromolecule localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. go-plus.json cellular macromolecule localisation http://purl.obolibrary.org/obo/GO_0070727 GO:0070728 biolink:MolecularActivity leucine binding Binding to 2-amino-4-methylpentanoic acid. go-plus.json Leu binding http://purl.obolibrary.org/obo/GO_0070728 GO:0070725 biolink:CellularComponent Yb body A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell. go-plus.json http://purl.obolibrary.org/obo/GO_0070725 GO:0070726 biolink:BiologicalProcess cell wall assembly The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0070726 GO:0045789 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045789 GO:0070723 biolink:BiologicalProcess response to cholesterol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0070723 GO:0070724 biolink:CellularComponent BMP receptor complex A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits. go-plus.json bone morphogenetic protein receptor complex http://purl.obolibrary.org/obo/GO_0070724 GO:0070721 biolink:CellularComponent ISGF3 complex A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein. go-plus.json interferon-stimulated gene factor 3 transcription complex http://purl.obolibrary.org/obo/GO_0070721 GO:0055102 biolink:MolecularActivity lipase inhibitor activity Binds to and stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0055102 GO:0021754 biolink:BiologicalProcess facial nucleus development The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021754 GO:0070722 biolink:CellularComponent Tle3-Aes complex A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product. go-plus.json Grg3b-Grg5 complex http://purl.obolibrary.org/obo/GO_0070722 GO:0055103 biolink:MolecularActivity ligase regulator activity Binds to and modulates the activity of a ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0055103 GO:0021755 biolink:BiologicalProcess eurydendroid cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts. go-plus.json http://purl.obolibrary.org/obo/GO_0021755 GO:0021756 biolink:BiologicalProcess striatum development The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. go-plus.json striate nucleus development|neostriatum development http://purl.obolibrary.org/obo/GO_0021756 GO:0055104 biolink:MolecularActivity ligase inhibitor activity Binds to and stops, prevents or reduces the activity of a ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0055104 GO:0070720 biolink:CellularComponent Grb2-SHP-2 complex A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway. go-plus.json GRB2-SHP-2 complex, PDGF stimulated http://purl.obolibrary.org/obo/GO_0070720 GO:0055105 biolink:MolecularActivity ubiquitin-protein transferase inhibitor activity Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase. go-plus.json http://purl.obolibrary.org/obo/GO_0055105 GO:0021757 biolink:BiologicalProcess caudate nucleus development The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. go-plus.json http://purl.obolibrary.org/obo/GO_0021757 GO:0021758 biolink:BiologicalProcess putamen development The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. go-plus.json http://purl.obolibrary.org/obo/GO_0021758 GO:0021759 biolink:BiologicalProcess globus pallidus development The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. go-plus.json pallidum development http://purl.obolibrary.org/obo/GO_0021759 GO:0055100 biolink:MolecularActivity adiponectin binding Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0055100 GO:0055101 biolink:MolecularActivity obsolete glycerophospholipase inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid. go-plus.json glycerophospholipase inhibitor activity http://purl.obolibrary.org/obo/GO_0055101 GO:0045790 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045790 GO:0045791 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045791 GO:0006108 biolink:BiologicalProcess malate metabolic process The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. go-plus.json malate metabolism http://purl.obolibrary.org/obo/GO_0006108 GO:0006109 biolink:BiologicalProcess regulation of carbohydrate metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. go-plus.json regulation of carbohydrate metabolism http://purl.obolibrary.org/obo/GO_0006109 GO:0055117 biolink:BiologicalProcess regulation of cardiac muscle contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0055117 GO:0006106 biolink:BiologicalProcess fumarate metabolic process The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate. go-plus.json fumarate metabolism http://purl.obolibrary.org/obo/GO_0006106 GO:0006107 biolink:BiologicalProcess oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle. go-plus.json oxaloacetate metabolism http://purl.obolibrary.org/obo/GO_0006107 GO:0055118 biolink:BiologicalProcess negative regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0055118 GO:0021740 biolink:BiologicalProcess principal sensory nucleus of trigeminal nerve development The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure. go-plus.json pontine nucleus development http://purl.obolibrary.org/obo/GO_0021740 GO:0055119 biolink:BiologicalProcess relaxation of cardiac muscle The process in which the extent of cardiac muscle contraction is reduced. go-plus.json http://purl.obolibrary.org/obo/GO_0055119 GO:0021741 biolink:BiologicalProcess spinal trigeminal nucleus development The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021741 GO:0006104 biolink:BiologicalProcess succinyl-CoA metabolic process The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A. go-plus.json succinyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0006104 GO:0006105 biolink:BiologicalProcess succinate metabolic process The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle. go-plus.json succinate metabolism http://purl.obolibrary.org/obo/GO_0006105 GO:0021742 biolink:BiologicalProcess abducens nucleus development The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021742 GO:0006102 biolink:BiologicalProcess isocitrate metabolic process The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle. go-plus.json isocitrate metabolism http://purl.obolibrary.org/obo/GO_0006102 GO:0045798 biolink:BiologicalProcess negative regulation of chromatin assembly or disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin assembly or disassembly. go-plus.json down-regulation of chromatin assembly or disassembly|inhibition of chromatin assembly or disassembly|negative regulation of chromatin assembly/disassembly|down regulation of chromatin assembly or disassembly|downregulation of chromatin assembly or disassembly http://purl.obolibrary.org/obo/GO_0045798 GO:0045799 biolink:BiologicalProcess positive regulation of chromatin assembly or disassembly Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly. go-plus.json up regulation of chromatin assembly or disassembly|activation of chromatin assembly or disassembly|stimulation of chromatin assembly or disassembly|up-regulation of chromatin assembly or disassembly|upregulation of chromatin assembly or disassembly|positive regulation of chromatin assembly/disassembly http://purl.obolibrary.org/obo/GO_0045799 GO:0006103 biolink:BiologicalProcess 2-oxoglutarate metabolic process The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. go-plus.json alpha-ketoglutarate metabolic process|2-ketoglutarate metabolism|2-oxoglutarate metabolism|alpha-ketoglutarate metabolism|2-ketoglutarate metabolic process|alpha-oxoglutarate metabolic process|alpha-oxoglutarate metabolism http://purl.obolibrary.org/obo/GO_0006103 GO:0006100 biolink:BiologicalProcess obsolete tricarboxylic acid cycle intermediate metabolic process OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle. go-plus.json citric acid cycle intermediate metabolic process|citric acid cycle intermediate metabolism|TCA intermediate metabolic process|tricarboxylic acid cycle intermediate metabolic process|Krebs cycle intermediate metabolic process|Krebs cycle intermediate metabolism|tricarboxylic acid cycle intermediate metabolism|TCA intermediate metabolism http://purl.obolibrary.org/obo/GO_0006100 GO:0045796 biolink:BiologicalProcess negative regulation of intestinal cholesterol absorption Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine. go-plus.json downregulation of cholesterol absorption|down regulation of cholesterol absorption|inhibition of cholesterol absorption|down-regulation of cholesterol absorption http://purl.obolibrary.org/obo/GO_0045796 GO:0045797 biolink:BiologicalProcess positive regulation of intestinal cholesterol absorption Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine. go-plus.json up regulation of cholesterol absorption|upregulation of cholesterol absorption|stimulation of cholesterol absorption|up-regulation of cholesterol absorption|activation of cholesterol absorption http://purl.obolibrary.org/obo/GO_0045797 GO:0006101 biolink:BiologicalProcess citrate metabolic process The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle. go-plus.json citrate metabolism http://purl.obolibrary.org/obo/GO_0006101 GO:0045794 biolink:BiologicalProcess negative regulation of cell volume Any process that decreases cell volume. go-plus.json RVD|cell regulatory volume decrease http://purl.obolibrary.org/obo/GO_0045794 GO:0045795 biolink:BiologicalProcess positive regulation of cell volume Any process that increases cell volume. go-plus.json http://purl.obolibrary.org/obo/GO_0045795 GO:0045792 biolink:BiologicalProcess negative regulation of cell size Any process that reduces cell size. go-plus.json inhibition of cell size|down regulation of cell size|downregulation of cell size|down-regulation of cell size http://purl.obolibrary.org/obo/GO_0045792 GO:0045793 biolink:BiologicalProcess positive regulation of cell size Any process that increases cell size. go-plus.json up-regulation of cell size|upregulation of cell size|up regulation of cell size|activation of cell size|stimulation of cell size http://purl.obolibrary.org/obo/GO_0045793 GO:0070758 biolink:BiologicalProcess regulation of interleukin-35-mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor. go-plus.json regulation of IL-35-mediated signaling pathway|regulation of interleukin-35-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070758 GO:0070759 biolink:BiologicalProcess negative regulation of interleukin-35-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor. go-plus.json negative regulation of interleukin-35-mediated signalling pathway|negative regulation of IL-35-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070759 GO:0070756 biolink:BiologicalProcess positive regulation of interleukin-35 production Any process that activates or increases the frequency, rate, or extent of interleukin-35 production. go-plus.json upregulation of interleukin-35 production|up regulation of interleukin-35 production|activation of interleukin-35 production|stimulation of interleukin-35 production|positive regulation of interleukin-35 biosynthetic process|positive regulation of IL-35 production|up-regulation of interleukin-35 production http://purl.obolibrary.org/obo/GO_0070756 GO:0070757 biolink:BiologicalProcess interleukin-35-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-35-mediated signalling pathway|IL-35-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070757 GO:0070754 biolink:BiologicalProcess regulation of interleukin-35 production Any process that modulates the frequency, rate, or extent of interleukin-35 production. go-plus.json regulation of interleukin-35 biosynthetic process|regulation of IL-35 production http://purl.obolibrary.org/obo/GO_0070754 GO:0055113 biolink:BiologicalProcess epiboly involved in gastrulation with mouth forming second The expansion of one cell sheet over other cells involved in deuterostomic gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0055113 GO:0021743 biolink:BiologicalProcess hypoglossal nucleus development The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021743 GO:0055114 biolink:BiologicalProcess obsolete oxidation-reduction process OBSOLETE. A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. go-plus.json oxidoreductase process|oxidation reduction http://purl.obolibrary.org/obo/GO_0055114 GO:0070755 biolink:BiologicalProcess negative regulation of interleukin-35 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production. go-plus.json down regulation of interleukin-35 production|downregulation of interleukin-35 production|negative regulation of IL-35 production|down-regulation of interleukin-35 production|negative regulation of interleukin-35 biosynthetic process|inhibition of interleukin-35 production http://purl.obolibrary.org/obo/GO_0070755 GO:0021744 biolink:BiologicalProcess dorsal motor nucleus of vagus nerve development The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021744 GO:0055115 biolink:BiologicalProcess entry into diapause The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation. Wikipedia:Diapause go-plus.json http://purl.obolibrary.org/obo/GO_0055115 GO:0070752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070752 GO:0021745 biolink:BiologicalProcess nucleus ambiguus development The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021745 GO:0070753 biolink:BiologicalProcess interleukin-35 production The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-35 production|interleukin-35 secretion|interleukin-35 biosynthetic process http://purl.obolibrary.org/obo/GO_0070753 gocheck_do_not_annotate GO:0055116 biolink:BiologicalProcess entry into reproductive diapause The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0055116 GO:0021746 biolink:BiologicalProcess solitary nucleus development The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021746 GO:0070750 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070750 GO:0021747 biolink:BiologicalProcess cochlear nucleus development The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021747 GO:0055110 biolink:BiologicalProcess involution involved in gastrulation with mouth forming second The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0055110 GO:0070751 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070751 GO:0021748 biolink:BiologicalProcess dorsal cochlear nucleus development The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021748 GO:0021749 biolink:BiologicalProcess ventral cochlear nucleus development The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021749 GO:0055111 biolink:BiologicalProcess ingression involved in gastrulation with mouth forming second The migration of individual cells into the embryo involved in deuterostomic gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0055111 GO:0055112 biolink:BiologicalProcess delamination involved in gastrulation with mouth forming second The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0055112 GO:0006119 biolink:BiologicalProcess oxidative phosphorylation The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. Wikipedia:Oxidative_phosphorylation go-plus.json respiratory-chain phosphorylation http://purl.obolibrary.org/obo/GO_0006119 goslim_pir GO:0006117 biolink:BiologicalProcess acetaldehyde metabolic process The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. go-plus.json acetaldehyde metabolism|ethanal metabolism|ethanal metabolic process http://purl.obolibrary.org/obo/GO_0006117 GO:0055128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055128 GO:0006118 biolink:BiologicalProcess obsolete electron transport OBSOLETE. The transport of electrons from an electron donor to an electron acceptor. go-plus.json oxidized glutathione reduction|protein-disulfide reduction|electron transport|6-phosphofructokinase reduction|electron transfer|other pathways of electron transport|dihydrolipoamide reduction|dihydrobiopterin reduction|dihydrolipoylprotein reduction|dihydropteridine reduction http://purl.obolibrary.org/obo/GO_0006118 GO:0055129 biolink:BiologicalProcess L-proline biosynthetic process The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. go-plus.json pyrrolidine-2-carboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0055129 GO:0006115 biolink:BiologicalProcess ethanol biosynthetic process The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. go-plus.json ethanol biosynthesis|ethanol anabolism|ethanol synthesis|ethanol formation http://purl.obolibrary.org/obo/GO_0006115 GO:0021730 biolink:BiologicalProcess trigeminal sensory nucleus development The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021730 GO:0006116 biolink:BiologicalProcess NADH oxidation A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD. go-plus.json NADH dehydrogenation|reduced nicotinamide adenine dinucleotide dehydrogenation|reduced nicotinamide adenine dinucleotide oxidation|reduced NAD dehydrogenation|reduced NAD oxidation|NAD (reduced) dehydrogenation|NAD (reduced) oxidation http://purl.obolibrary.org/obo/GO_0006116 GO:0021731 biolink:BiologicalProcess trigeminal motor nucleus development The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021731 GO:0006113 biolink:BiologicalProcess fermentation The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP). Wikipedia:Fermentation_(biochemistry)|MetaCyc:FERMENTATION-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0006113 goslim_pir GO:0006114 biolink:BiologicalProcess glycerol biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. go-plus.json glycerol synthesis|glycerol formation|glycerol biosynthesis|glycerol anabolism http://purl.obolibrary.org/obo/GO_0006114 GO:0006111 biolink:BiologicalProcess regulation of gluconeogenesis Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. go-plus.json regulation of gluconeogenesis involved in cellular glucose homeostasis|regulation of glucose biosynthesis|regulation of glucose biosynthetic process http://purl.obolibrary.org/obo/GO_0006111 GO:0006112 biolink:BiologicalProcess energy reserve metabolic process The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. go-plus.json energy reserve metabolism http://purl.obolibrary.org/obo/GO_0006112 goslim_pir GO:0006110 biolink:BiologicalProcess regulation of glycolytic process Any process that modulates the frequency, rate or extent of glycolysis. go-plus.json regulation of glycolysis involved in cellular glucose homeostasis http://purl.obolibrary.org/obo/GO_0006110 GO:0070749 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070749 GO:0070747 biolink:MolecularActivity interleukin-35 receptor activity Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-35R|IL-35 receptor activity http://purl.obolibrary.org/obo/GO_0070747 GO:0070748 biolink:MolecularActivity interleukin-35 receptor binding Binding to an interleukin-35 receptor. go-plus.json interleukin-35 receptor ligand|IL-35 http://purl.obolibrary.org/obo/GO_0070748 GO:0070745 biolink:CellularComponent interleukin-35 complex A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space. go-plus.json IL12A|IL-35 complex|p35|EBI3 http://purl.obolibrary.org/obo/GO_0070745 GO:0070746 biolink:MolecularActivity interleukin-35 binding Binding to interleukin-35. go-plus.json IL-35 binding http://purl.obolibrary.org/obo/GO_0070746 GO:0021732 biolink:BiologicalProcess midbrain-hindbrain boundary maturation A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json isthmus maturation|MHB maturation http://purl.obolibrary.org/obo/GO_0021732 GO:0055124 biolink:BiologicalProcess obsolete premature neural plate formation OBSOLETE. The formation of the neural plate before the appropriate time. go-plus.json premature neural plate formation http://purl.obolibrary.org/obo/GO_0055124 GO:0070743 biolink:CellularComponent interleukin-23 complex A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space. go-plus.json IL12B|IL23A|p19|IL-23 complex|p40 http://purl.obolibrary.org/obo/GO_0070743 GO:0055125 biolink:CellularComponent obsolete Nic96 complex OBSOLETE. A protein complex that forms part of the nuclear pore complex, and is required for its correct assembly. In Saccharomyces cerevisiae Nic96 contains Nsp1p, Nup57p, Nup49p, and Nic96p. go-plus.json Nic96 complex http://purl.obolibrary.org/obo/GO_0055125 GO:0021733 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0021733 GO:0070744 biolink:CellularComponent interleukin-27 complex A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space. go-plus.json IL-27 complex|p28|IL27|EBI3 http://purl.obolibrary.org/obo/GO_0070744 GO:0070741 biolink:BiologicalProcess response to interleukin-6 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus. go-plus.json response to IL-6 http://purl.obolibrary.org/obo/GO_0070741 GO:0021734 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0021734 GO:0055126 biolink:CellularComponent obsolete Nup82 complex OBSOLETE. A protein complex that forms part of the nuclear pore complex. It forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p, and is required for proper localization of Nup116p. In Saccharomyces cerevisiae this complex contains Nup82p, Nsp1p, Nup159p, Nup116p, and Gle2p. go-plus.json Nup82 complex http://purl.obolibrary.org/obo/GO_0055126 GO:0055127 biolink:BiologicalProcess vibrational conductance of sound to the inner ear The transmission of vibrations via ossicles to the inner ear. go-plus.json http://purl.obolibrary.org/obo/GO_0055127 GO:0070742 biolink:MolecularActivity C2H2 zinc finger domain binding Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion. go-plus.json http://purl.obolibrary.org/obo/GO_0070742 GO:0021735 biolink:BiologicalProcess dentate nucleus development The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021735 GO:0055120 biolink:CellularComponent striated muscle dense body A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere. go-plus.json http://purl.obolibrary.org/obo/GO_0055120 GO:0021736 biolink:BiologicalProcess globose nucleus development The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021736 GO:0055121 biolink:BiologicalProcess response to high fluence blue light stimulus by blue high-fluence system Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2. go-plus.json response to high fluence blue light|response to high fluence blue light by bhf system http://purl.obolibrary.org/obo/GO_0055121 GO:0070740 biolink:MolecularActivity tubulin-glutamic acid ligase activity Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule. Reactome:R-HSA-8865774|Reactome:R-HSA-8955869 go-plus.json tubulin-glutamate ligase activity|tubulin glutamylase activity http://purl.obolibrary.org/obo/GO_0070740 GO:0021737 biolink:BiologicalProcess emboliform nucleus development The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021737 GO:0021738 biolink:BiologicalProcess fastigial nucleus development The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021738 GO:0055122 biolink:BiologicalProcess response to very low light intensity stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec. go-plus.json http://purl.obolibrary.org/obo/GO_0055122 GO:0055123 biolink:BiologicalProcess digestive system development The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0055123 GO:0021739 biolink:BiologicalProcess mesencephalic trigeminal nucleus development The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021739 GO:0021720 biolink:BiologicalProcess superior olivary nucleus formation The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. go-plus.json http://purl.obolibrary.org/obo/GO_0021720 GO:0021729 biolink:BiologicalProcess superior reticular formation development The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021729 GO:0055130 biolink:BiologicalProcess D-alanine catabolic process The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine. go-plus.json (2R)-2-aminopropanoic acid catabolic process http://purl.obolibrary.org/obo/GO_0055130 GO:0070778 biolink:BiologicalProcess L-aspartate transmembrane transport The directed movement of L-aspartate across a membrane. go-plus.json L-aspartate transport http://purl.obolibrary.org/obo/GO_0070778 GO:0070779 biolink:BiologicalProcess D-aspartate import across plasma membrane The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. go-plus.json D-aspartate import into cell|D-aspartate uptake|D-aspartate import http://purl.obolibrary.org/obo/GO_0070779 GO:0070776 biolink:CellularComponent MOZ/MORF histone acetyltransferase complex A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. go-plus.json http://purl.obolibrary.org/obo/GO_0070776 GO:0021721 biolink:BiologicalProcess superior olivary nucleus structural organization The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. go-plus.json superior olivary nucleus structural organisation http://purl.obolibrary.org/obo/GO_0021721 GO:0070777 biolink:BiologicalProcess D-aspartate transport The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0070777 GO:0021722 biolink:BiologicalProcess superior olivary nucleus maturation A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. go-plus.json superior olive maturation http://purl.obolibrary.org/obo/GO_0021722 GO:0021723 biolink:BiologicalProcess medullary reticular formation development The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata. go-plus.json rhombencephalic reticular formation development http://purl.obolibrary.org/obo/GO_0021723 GO:0070774 biolink:MolecularActivity phytoceramidase activity Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine. Reactome:R-HSA-428262|MetaCyc:CERAMIDASE-YEAST-RXN|KEGG_REACTION:R06528 go-plus.json http://purl.obolibrary.org/obo/GO_0070774 GO:0070775 biolink:CellularComponent H3 histone acetyltransferase complex A multisubunit complex that catalyzes the acetylation of histone H3. go-plus.json H3 HAT complex http://purl.obolibrary.org/obo/GO_0070775 GO:0021724 biolink:BiologicalProcess inferior raphe nucleus development The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure. go-plus.json inferior central nucleus development|posterior raphe nucleus development http://purl.obolibrary.org/obo/GO_0021724 GO:0055131 biolink:MolecularActivity C3HC4-type RING finger domain binding Binding to a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0055131 GO:0021725 biolink:BiologicalProcess superior raphe nucleus development The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure. go-plus.json anterior raphe nucleus development|superior central nucleus development http://purl.obolibrary.org/obo/GO_0021725 GO:0070772 biolink:CellularComponent PAS complex A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p. go-plus.json autophagy-specific phosphatidylinositol 3-kinase complex http://purl.obolibrary.org/obo/GO_0070772 GO:0021726 biolink:BiologicalProcess lateral reticular nucleus development The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021726 GO:0055132 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055132 GO:0070773 biolink:MolecularActivity protein-N-terminal glutamine amidohydrolase activity Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein. go-plus.json NtQ-amidase activity http://purl.obolibrary.org/obo/GO_0070773 GO:0055133 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055133 GO:0070770 biolink:CellularComponent alphaIIb-beta3 integrin-CD47-FAK complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK. go-plus.json ITGA2b-ITGB3-CD47-FAK complex http://purl.obolibrary.org/obo/GO_0070770 GO:0021727 biolink:BiologicalProcess intermediate reticular formation development The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure. go-plus.json intermediate reticular nucleus development http://purl.obolibrary.org/obo/GO_0021727 GO:0070771 biolink:CellularComponent alphaIIb-beta3 integrin-CD47-Src complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src. go-plus.json ITGA2b-ITGB3-CD47-SRC complex http://purl.obolibrary.org/obo/GO_0070771 GO:0055134 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055134 GO:0021728 biolink:BiologicalProcess inferior reticular formation development The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021728 GO:0021718 biolink:BiologicalProcess superior olivary nucleus development The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. go-plus.json superior olive development http://purl.obolibrary.org/obo/GO_0021718 GO:0021719 biolink:BiologicalProcess superior olivary nucleus morphogenesis The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. go-plus.json superior olive morphogenesis http://purl.obolibrary.org/obo/GO_0021719 GO:0070769 biolink:CellularComponent alphaIIb-beta3 integrin-CIB complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin. go-plus.json ITGA2B-ITGB3-CIB1 complex http://purl.obolibrary.org/obo/GO_0070769 GO:0070767 biolink:CellularComponent BRCA1-Rad51 complex A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity. go-plus.json http://purl.obolibrary.org/obo/GO_0070767 GO:0070768 biolink:CellularComponent synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof). go-plus.json Snap25-Syt1-Unc13b-Vamp2-Stx1b2-Stx1a complex|SNARE complex (Snap25, Syt1, Unc13b, Vamp2, Stx1b2, Stx1a) http://purl.obolibrary.org/obo/GO_0070768 GO:0070765 biolink:CellularComponent gamma-secretase complex A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein. go-plus.json presenilin complex|CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)|gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)|PS2 complex|PS1 complex|gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant) http://purl.obolibrary.org/obo/GO_0070765 GO:0021710 biolink:BiologicalProcess cerebellar stellate cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021710 GO:0021711 biolink:BiologicalProcess cerebellar unipolar brush cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021711 GO:0070766 biolink:CellularComponent endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof). go-plus.json SNARE complex (Stx4, Napa, Vamp3, Nsf, Vamp2)|Stx4-Napa-Vamp3-Nsf-Vamp2 complex http://purl.obolibrary.org/obo/GO_0070766 GO:0021712 biolink:BiologicalProcess candelabrum cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021712 GO:0070763 biolink:CellularComponent Delta1 complex A protein complex that consists of homodimer of the Notch ligand Delta1. go-plus.json Delta1 homodimer complex http://purl.obolibrary.org/obo/GO_0070763 GO:0021713 biolink:BiologicalProcess inferior olivary nucleus development The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. go-plus.json inferior olive development http://purl.obolibrary.org/obo/GO_0021713 GO:0070764 biolink:CellularComponent gamma-secretase-Delta1 complex A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070764 GO:0021714 biolink:BiologicalProcess inferior olivary nucleus morphogenesis The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. go-plus.json inferior olive morphogenesis http://purl.obolibrary.org/obo/GO_0021714 GO:0070761 biolink:CellularComponent pre-snoRNP complex A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes. go-plus.json pre-small nucleolar ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0070761 GO:0021715 biolink:BiologicalProcess inferior olivary nucleus formation The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. go-plus.json inferior olive biosynthesis|inferior olive formation http://purl.obolibrary.org/obo/GO_0021715 GO:0070762 biolink:CellularComponent nuclear pore transmembrane ring A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex. go-plus.json NDC1 complex|NDC1 subcomplex http://purl.obolibrary.org/obo/GO_0070762 GO:0021716 biolink:BiologicalProcess inferior olivary nucleus structural organization The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. go-plus.json inferior olive structural organization|inferior olivary nucleus structural organisation http://purl.obolibrary.org/obo/GO_0021716 GO:0021717 biolink:BiologicalProcess inferior olivary nucleus maturation A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. go-plus.json inferior olive maturation http://purl.obolibrary.org/obo/GO_0021717 GO:0070760 biolink:BiologicalProcess positive regulation of interleukin-35-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor. go-plus.json positive regulation of interleukin-35-mediated signalling pathway|positive regulation of IL-35-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070760 CHEBI:71993 biolink:ChemicalSubstance flavonol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71993 GO:0031182 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031182 NCBITaxon:171 biolink:OrganismalEntity Leptospira go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_171 GO:0031183 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031183 GO:0031180 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031180 GO:0031181 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031181 NCBITaxon:170 biolink:OrganismalEntity Leptospiraceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_170 NCBITaxon:173 biolink:OrganismalEntity Leptospira interrogans go-plus.json Spirochaeta icterohaemorrhagiae|Spirochaeta biflexa|Spirochaeta nodosa|Spirochaeta interrogans|Spirochaeta icterogenes|Leptospira icteroides http://purl.obolibrary.org/obo/NCBITaxon_173 GO:0031188 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031188 GO:0031189 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031189 GO:0031186 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031186 GO:0031187 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031187 GO:0031184 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031184 GO:0031185 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031185 GO:0031171 biolink:BiologicalProcess ferricrocin biosynthetic process The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3. go-plus.json ferricrocin synthesis|ferricrocin formation|ferricrocin biosynthetic process, peptide modification|ferricrocin biosynthesis|ferricrocin biosynthetic process, peptide formation|ferricrocin anabolism http://purl.obolibrary.org/obo/GO_0031171 GO:0031172 biolink:MolecularActivity ornithine N5-monooxygenase activity Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O. MetaCyc:RXN-11128|RHEA:41508 go-plus.json L-ornithine 5-monooxygenase activity http://purl.obolibrary.org/obo/GO_0031172 GO:0031170 biolink:BiologicalProcess ferricrocin metabolic process The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3. go-plus.json ferricrocin metabolism http://purl.obolibrary.org/obo/GO_0031170 GO:0031179 biolink:BiologicalProcess peptide modification The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0031179 GO:0031177 biolink:MolecularActivity phosphopantetheine binding Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate). go-plus.json http://purl.obolibrary.org/obo/GO_0031177 GO:0031178 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031178 GO:0031175 biolink:BiologicalProcess neuron projection development The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). go-plus.json neurite growth|neurite outgrowth|neurite formation|neurite development|neurite biosynthesis http://purl.obolibrary.org/obo/GO_0031175 GO:0031176 biolink:MolecularActivity endo-1,4-beta-xylanase activity Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. EC:3.2.1.8|MetaCyc:3.2.1.8-RXN go-plus.json beta-1,4-xylanase activity|endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity|1,4-beta-xylan xylanohydrolase activity|endo-beta-1,4-xylanase activity|endo-1,4-beta-D-xylanase activity|beta-xylanase activity|xylanase|beta-D-xylanase activity|endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity|1,4-beta-D-xylan xylanohydrolase activity|beta-1,4-xylan xylanohydrolase activity|endo-1,4-xylanase activity http://purl.obolibrary.org/obo/GO_0031176 GO:0031173 biolink:BiologicalProcess otolith mineralization completed early in development The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear. go-plus.json otoconium mineralization|otoconia mineralization http://purl.obolibrary.org/obo/GO_0031173 GO:0031174 biolink:BiologicalProcess lifelong otolith mineralization The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added. go-plus.json http://purl.obolibrary.org/obo/GO_0031174 GO:0031160 biolink:CellularComponent spore wall The specialized envelope lying outside the cell membrane of a spore. go-plus.json spore coat http://purl.obolibrary.org/obo/GO_0031160 GO:0031161 biolink:BiologicalProcess phosphatidylinositol catabolic process The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. go-plus.json phosphatidylinositol degradation|PtdIns catabolic process|phosphatidylinositol catabolism|phosphatidylinositol breakdown|PtdIns catabolism http://purl.obolibrary.org/obo/GO_0031161 GO:0031168 biolink:BiologicalProcess ferrichrome metabolic process The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. go-plus.json ferrichrome metabolism http://purl.obolibrary.org/obo/GO_0031168 GO:0031169 biolink:BiologicalProcess ferrichrome biosynthetic process The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. go-plus.json ferrichrome anabolism|ferrichrome synthesis|ferrichrome formation|ferrichrome biosynthetic process, peptide modification|ferrichrome biosynthetic process, peptide formation|ferrichrome biosynthesis http://purl.obolibrary.org/obo/GO_0031169 GO:0031166 biolink:CellularComponent integral component of vacuolar membrane The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. go-plus.json integral to vacuolar membrane http://purl.obolibrary.org/obo/GO_0031166 GO:0031167 biolink:BiologicalProcess rRNA methylation The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031167 GO:0031164 biolink:CellularComponent contractile vacuolar membrane The lipid bilayer surrounding the contractile vacuole. go-plus.json contractile vacuole membrane http://purl.obolibrary.org/obo/GO_0031164 GO:0031165 biolink:CellularComponent integral component of contractile vacuolar membrane The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer. go-plus.json integral to contractile vacuolar membrane http://purl.obolibrary.org/obo/GO_0031165 GO:0031162 biolink:BiologicalProcess sulfur incorporation into metallo-sulfur cluster The incorporation of exogenous sulfur into a metallo-sulfur cluster. go-plus.json sulphur incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0031162 GO:0031163 biolink:BiologicalProcess metallo-sulfur cluster assembly The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster. go-plus.json metallo-sulfur cluster biosynthesis|metallo-sulphur cluster assembly|metal-sulfur cluster assembly http://purl.obolibrary.org/obo/GO_0031163 GO:0031159 biolink:BiologicalProcess positive regulation of aggregate size involved in sorocarp development Any process that increases the size of the aggregate formed during sorocarp formation. go-plus.json stimulation of aggregate size|activation of aggregate size|up-regulation of aggregate size|up regulation of aggregate size|upregulation of aggregate size http://purl.obolibrary.org/obo/GO_0031159 GO:0045700 biolink:BiologicalProcess regulation of spermatid nuclear differentiation Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045700 GO:0045707 biolink:BiologicalProcess regulation of adult salivary gland boundary specification Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism. go-plus.json regulation of adult salivary gland determination http://purl.obolibrary.org/obo/GO_0045707 GO:0031150 biolink:BiologicalProcess sorocarp stalk development The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum. go-plus.json stalk formation|stalk development|sorophore development http://purl.obolibrary.org/obo/GO_0031150 GO:0045708 biolink:BiologicalProcess regulation of larval salivary gland boundary specification Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism. go-plus.json regulation of larval salivary gland determination http://purl.obolibrary.org/obo/GO_0045708 GO:0045705 biolink:BiologicalProcess negative regulation of salivary gland boundary specification Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination. go-plus.json negative regulation of salivary gland determination|down-regulation of salivary gland determination|downregulation of salivary gland determination|down regulation of salivary gland determination|inhibition of salivary gland determination http://purl.obolibrary.org/obo/GO_0045705 GO:0045706 biolink:BiologicalProcess positive regulation of salivary gland boundary specification Any process that activates or increases the frequency, rate or extent of salivary gland determination. go-plus.json stimulation of salivary gland determination|up-regulation of salivary gland determination|activation of salivary gland determination|positive regulation of salivary gland determination|up regulation of salivary gland determination|upregulation of salivary gland determination http://purl.obolibrary.org/obo/GO_0045706 GO:0045703 biolink:MolecularActivity ketoreductase activity Catalysis of the reduction of a ketone group to form the corresponding alcohol. go-plus.json http://purl.obolibrary.org/obo/GO_0045703 GO:0045704 biolink:BiologicalProcess regulation of salivary gland boundary specification Any process that modulates the frequency, rate or extent of salivary gland determination. go-plus.json regulation of salivary gland determination http://purl.obolibrary.org/obo/GO_0045704 GO:0045701 biolink:BiologicalProcess negative regulation of spermatid nuclear differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation. go-plus.json inhibition of spermatid nuclear differentiation|down regulation of spermatid nuclear differentiation|downregulation of spermatid nuclear differentiation|down-regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_0045701 GO:0045702 biolink:BiologicalProcess positive regulation of spermatid nuclear differentiation Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation. go-plus.json up-regulation of spermatid nuclear differentiation|upregulation of spermatid nuclear differentiation|up regulation of spermatid nuclear differentiation|activation of spermatid nuclear differentiation|stimulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_0045702 GO:0031157 biolink:BiologicalProcess regulation of aggregate size involved in sorocarp development Any process that modulates the size of the aggregate formed during sorocarp formation. go-plus.json regulation of aggregation during fruiting body biosynthesis|regulation of aggregation during fruiting body formation http://purl.obolibrary.org/obo/GO_0031157 GO:0031158 biolink:BiologicalProcess negative regulation of aggregate size involved in sorocarp development Any process that decreases the size of the aggregate formed during sorocarp formation. go-plus.json down-regulation of aggregate size|downregulation of aggregate size|down regulation of aggregate size|inhibition of aggregate size http://purl.obolibrary.org/obo/GO_0031158 GO:0031155 biolink:BiologicalProcess regulation of reproductive fruiting body development Any process that modulates the frequency, rate or extent of reproductive fruiting body development. go-plus.json regulation of fruiting body formation http://purl.obolibrary.org/obo/GO_0031155 GO:0031156 biolink:BiologicalProcess regulation of sorocarp development Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum. go-plus.json regulation of fruiting body formation|regulation of fruiting body development http://purl.obolibrary.org/obo/GO_0031156 GO:0031153 biolink:BiologicalProcess slug development involved in sorocarp development The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development. go-plus.json slug development during fruiting body development|pseudoplasmodium biosynthesis|migratory slug development during sorocarp development|pseudoplasmodium formation|slug development during sorocarp development|standing slug development during sorocarp development http://purl.obolibrary.org/obo/GO_0031153 GO:0031154 biolink:BiologicalProcess culmination involved in sorocarp development The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development. go-plus.json culminant development|culmination during sorocarp development|culmination during fruiting body development http://purl.obolibrary.org/obo/GO_0031154 GO:0031151 biolink:MolecularActivity histone methyltransferase activity (H3-K79 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein. go-plus.json histone methylase activity (H3-K79 specific)|histone lysine N-methyltransferase activity (H3-K79 specific) http://purl.obolibrary.org/obo/GO_0031151 GO:0045709 biolink:BiologicalProcess negative regulation of adult salivary gland boundary specification Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism. go-plus.json negative regulation of adult salivary gland determination|down-regulation of adult salivary gland determination|downregulation of adult salivary gland determination|down regulation of adult salivary gland determination|inhibition of adult salivary gland determination http://purl.obolibrary.org/obo/GO_0045709 GO:0031152 biolink:BiologicalProcess aggregation involved in sorocarp development The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. go-plus.json aggregate development involved in sorocarp development|aggregation during fruiting body development http://purl.obolibrary.org/obo/GO_0031152 GO:0031148 biolink:BiologicalProcess DIF-1 biosynthetic process The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells. go-plus.json 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one anabolism|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one synthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one formation|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthetic process|DIF-1 biosynthesis http://purl.obolibrary.org/obo/GO_0031148 GO:0031149 biolink:BiologicalProcess sorocarp stalk cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum. go-plus.json stalk cell differentiation http://purl.obolibrary.org/obo/GO_0031149 GO:0045710 biolink:BiologicalProcess negative regulation of larval salivary gland boundary specification Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism. go-plus.json inhibition of larval salivary gland determination|down regulation of larval salivary gland determination|downregulation of larval salivary gland determination|negative regulation of larval salivary gland determination|down-regulation of larval salivary gland determination http://purl.obolibrary.org/obo/GO_0045710 GO:0045711 biolink:BiologicalProcess positive regulation of adult salivary gland boundary specification Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism. go-plus.json upregulation of adult salivary gland determination|stimulation of adult salivary gland determination|up-regulation of adult salivary gland determination|activation of adult salivary gland determination|positive regulation of adult salivary gland determination|up regulation of adult salivary gland determination http://purl.obolibrary.org/obo/GO_0045711 GO:0006188 biolink:BiologicalProcess IMP biosynthetic process The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate. go-plus.json IMP anabolism|IMP synthesis|IMP biosynthesis|IMP formation http://purl.obolibrary.org/obo/GO_0006188 GO:0006189 biolink:BiologicalProcess 'de novo' IMP biosynthetic process The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. go-plus.json 'de novo' IMP synthesis|'de novo' IMP formation|'de novo' IMP biosynthesis|'de novo' purine biosynthetic process|'de novo' purine biosynthesis|'de novo' IMP anabolism http://purl.obolibrary.org/obo/GO_0006189 GO:0006186 biolink:BiologicalProcess dGDP phosphorylation The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP. go-plus.json http://purl.obolibrary.org/obo/GO_0006186 GO:0006187 biolink:BiologicalProcess dGTP biosynthetic process from dGDP The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate. go-plus.json dGTP anabolism from dGDP|dGTP synthesis from dGDP|dGTP formation from dGDP http://purl.obolibrary.org/obo/GO_0006187 GO:0006184 biolink:BiologicalProcess obsolete GTP catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. go-plus.json GTP catabolism|GTP degradation|GTP breakdown|GTP hydrolysis http://purl.obolibrary.org/obo/GO_0006184 GO:0006185 biolink:BiologicalProcess dGDP biosynthetic process The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). go-plus.json dGDP anabolism|dGDP synthesis|dGDP formation|dGDP biosynthesis http://purl.obolibrary.org/obo/GO_0006185 GO:0006193 biolink:BiologicalProcess ITP catabolic process The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate. go-plus.json ITP hydrolysis|ITP degradation|ITP catabolism|ITP breakdown http://purl.obolibrary.org/obo/GO_0006193 GO:0045718 biolink:BiologicalProcess obsolete negative regulation of flagellum assembly OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a flagellum. go-plus.json downregulation of flagellum assembly|down regulation of flagellum assembly|negative regulation of flagellum biogenesis|inhibition of flagellum assembly|negative regulation of flagella assembly|down-regulation of flagellum assembly|negative regulation of flagellum assembly http://purl.obolibrary.org/obo/GO_0045718 GO:0045719 biolink:BiologicalProcess negative regulation of glycogen biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. go-plus.json down regulation of glycogen biosynthetic process|downregulation of glycogen biosynthetic process|negative regulation of glycogen anabolism|negative regulation of glycogen synthesis|negative regulation of glycogen formation|down-regulation of glycogen biosynthetic process|negative regulation of glycogen biosynthesis|inhibition of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0045719 GO:0006194 biolink:BiologicalProcess dIDP phosphorylation The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP. go-plus.json http://purl.obolibrary.org/obo/GO_0006194 GO:0045716 biolink:BiologicalProcess obsolete positive regulation of low-density lipoprotein particle receptor biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors. go-plus.json positive regulation of low-density lipoprotein receptor biosynthesis|activation of low-density lipoprotein receptor biosynthetic process|stimulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor biosynthetic process|up-regulation of low-density lipoprotein receptor biosynthetic process|upregulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor anabolism|positive regulation of low-density lipoprotein receptor synthesis|positive regulation of low-density lipoprotein receptor formation|up regulation of low-density lipoprotein receptor biosynthetic process http://purl.obolibrary.org/obo/GO_0045716 GO:0006191 biolink:BiologicalProcess deoxyinosine salvage Any process that generates deoxyinosine from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0006191 GO:0045717 biolink:BiologicalProcess negative regulation of fatty acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. go-plus.json inhibition of fatty acid biosynthetic process|down regulation of fatty acid biosynthetic process|downregulation of fatty acid biosynthetic process|negative regulation of fatty acid anabolism|negative regulation of fatty acid synthesis|negative regulation of fatty acid biosynthesis|down-regulation of fatty acid biosynthetic process|negative regulation of fatty acid formation http://purl.obolibrary.org/obo/GO_0045717 GO:0006192 biolink:BiologicalProcess IDP phosphorylation The process of introducing a phosphate group into IDP, inosine (5'-)diphosphate, to produce ITP. go-plus.json http://purl.obolibrary.org/obo/GO_0006192 GO:0045714 biolink:BiologicalProcess obsolete regulation of low-density lipoprotein particle receptor biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors. go-plus.json regulation of low-density lipoprotein receptor formation|regulation of low-density lipoprotein receptor biosynthetic process|regulation of LDLr biosynthesis|regulation of LDLr biosynthetic process|regulation of low-density lipoprotein receptor biosynthesis|regulation of low-density lipoprotein receptor anabolism|regulation of low-density lipoprotein receptor synthesis http://purl.obolibrary.org/obo/GO_0045714 GO:0006190 biolink:BiologicalProcess inosine salvage Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis. go-plus.json adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0006190 GO:0045715 biolink:BiologicalProcess obsolete negative regulation of low-density lipoprotein particle receptor biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors. go-plus.json down-regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor biosynthesis|inhibition of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor anabolism|negative regulation of low-density lipoprotein receptor synthesis|negative regulation of low-density lipoprotein receptor formation|down regulation of low-density lipoprotein receptor biosynthetic process|downregulation of low-density lipoprotein receptor biosynthetic process http://purl.obolibrary.org/obo/GO_0045715 GO:0045712 biolink:BiologicalProcess positive regulation of larval salivary gland boundary specification Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism. go-plus.json up-regulation of larval salivary gland determination|upregulation of larval salivary gland determination|positive regulation of larval salivary gland determination|up regulation of larval salivary gland determination|activation of larval salivary gland determination|stimulation of larval salivary gland determination http://purl.obolibrary.org/obo/GO_0045712 GO:0045713 biolink:BiologicalProcess obsolete low-density lipoprotein particle receptor biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells. go-plus.json low-density lipoprotein receptor biosynthesis|low-density lipoprotein receptor anabolism|low-density lipoprotein receptor biosynthetic process|low-density lipoprotein receptor synthesis|low-density lipoprotein receptor formation|LDLr biosynthetic process|LDLr biosynthesis http://purl.obolibrary.org/obo/GO_0045713 GO:0031146 biolink:BiologicalProcess SCF-dependent proteasomal ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. go-plus.json SCF-dependent proteasomal ubiquitin-dependent protein degradation|SCF-dependent proteasomal ubiquitin-dependent protein catabolism|SCF-dependent proteasomal ubiquitin-dependent protein breakdown http://purl.obolibrary.org/obo/GO_0031146 GO:0031147 biolink:BiologicalProcess 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells. go-plus.json DIF-1 metabolic process|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolism|DIF-1 metabolism http://purl.obolibrary.org/obo/GO_0031147 GO:0031144 biolink:BiologicalProcess proteasome localization Any process in which the proteasome is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of proteasome localization|proteasome localisation http://purl.obolibrary.org/obo/GO_0031144 GO:0031145 biolink:BiologicalProcess anaphase-promoting complex-dependent catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome. go-plus.json anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein degradation|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism|degradation of cyclin|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein breakdown|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cyclin catabolism|cyclin degradation|APC-dependent proteasomal ubiquitin-dependent protein catabolism|cyclin breakdown|negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation|cyclin catabolic process|APC-dependent proteasomal ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_0031145 GO:0031142 biolink:BiologicalProcess induction of conjugation upon nitrogen starvation The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0031142 GO:0031143 biolink:CellularComponent pseudopodium A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding. Wikipedia:Pseudopod go-plus.json reticulopodium|axopodium|pseudopodial protrusion|lobopodium|pseudopod http://purl.obolibrary.org/obo/GO_0031143 goslim_pir GO:0031140 biolink:BiologicalProcess induction of conjugation upon nutrient starvation The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients. go-plus.json http://purl.obolibrary.org/obo/GO_0031140 GO:0031141 biolink:BiologicalProcess induction of conjugation upon carbon starvation The process in which a cell initiates conjugation with cellular fusion upon carbon starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0031141 GO:0031139 biolink:BiologicalProcess positive regulation of conjugation with cellular fusion Any process that increases the rate or frequency of conjugation with cellular fusion. go-plus.json upregulation of conjugation with cellular fusion|stimulation of conjugation with cellular fusion|activation of conjugation with cellular fusion|up-regulation of conjugation with cellular fusion|up regulation of conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0031139 GO:0031137 biolink:BiologicalProcess regulation of conjugation with cellular fusion Any process that modulates the rate or frequency of conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0031137 GO:0031138 biolink:BiologicalProcess negative regulation of conjugation with cellular fusion Any process that decreases the rate or frequency of conjugation with cellular fusion. go-plus.json down-regulation of conjugation with cellular fusion|downregulation of conjugation with cellular fusion|down regulation of conjugation with cellular fusion|inhibition of conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0031138 GO:0045721 biolink:BiologicalProcess negative regulation of gluconeogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. go-plus.json downregulation of gluconeogenesis|down-regulation of gluconeogenesis|inhibition of gluconeogenesis|down regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0045721 GO:0045722 biolink:BiologicalProcess positive regulation of gluconeogenesis Any process that activates or increases the frequency, rate or extent of gluconeogenesis. go-plus.json up regulation of gluconeogenesis|activation of gluconeogenesis|stimulation of gluconeogenesis|up-regulation of gluconeogenesis|upregulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0045722 GO:0006199 biolink:BiologicalProcess obsolete ADP reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json ADP reduction http://purl.obolibrary.org/obo/GO_0006199 GO:0045720 biolink:BiologicalProcess negative regulation of integrin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. go-plus.json negative regulation of integrin synthesis|down regulation of integrin biosynthetic process|negative regulation of integrin formation|downregulation of integrin biosynthetic process|negative regulation of integrin biosynthesis|down-regulation of integrin biosynthetic process|inhibition of integrin biosynthetic process|negative regulation of integrin anabolism http://purl.obolibrary.org/obo/GO_0045720 GO:0006197 biolink:BiologicalProcess obsolete adenylate deaminase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json adenylate deaminase reaction http://purl.obolibrary.org/obo/GO_0006197 GO:0006198 biolink:BiologicalProcess cAMP catabolic process The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json cAMP breakdown|3',5'-cAMP catabolic process|adenosine 3',5'-cyclophosphate catabolic process|cyclic AMP catabolic process|3',5' cAMP catabolism|3',5' cAMP catabolic process|cyclic AMP catabolism|cAMP catabolism|adenosine 3',5'-cyclophosphate catabolism|3',5'-cAMP catabolism|cAMP degradation http://purl.obolibrary.org/obo/GO_0006198 GO:0006195 biolink:BiologicalProcess purine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine nucleotide breakdown|purine nucleotide catabolism|purine nucleotide degradation http://purl.obolibrary.org/obo/GO_0006195 GO:0006196 biolink:BiologicalProcess AMP catabolic process The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate. go-plus.json AMP catabolism|AMP degradation|AMP breakdown http://purl.obolibrary.org/obo/GO_0006196 GO:0045729 biolink:BiologicalProcess respiratory burst at fertilization The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes. go-plus.json oxidative burst at fertilization|metabolic burst at fertilization http://purl.obolibrary.org/obo/GO_0045729 GO:0045727 biolink:BiologicalProcess positive regulation of translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. go-plus.json positive regulation of protein formation|upregulation of protein biosynthetic process|stimulation of protein biosynthetic process|up-regulation of protein biosynthetic process|activation of protein biosynthetic process|positive regulation of protein biosynthetic process|positive regulation of protein biosynthesis|up regulation of protein biosynthetic process|positive regulation of protein anabolism|positive regulation of protein synthesis http://purl.obolibrary.org/obo/GO_0045727 GO:0045728 biolink:BiologicalProcess respiratory burst after phagocytosis A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity. go-plus.json metabolic burst after phagocytosis|oxidative burst after phagocytosis http://purl.obolibrary.org/obo/GO_0045728 GO:0045725 biolink:BiologicalProcess positive regulation of glycogen biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. go-plus.json up-regulation of glycogen biosynthetic process|upregulation of glycogen biosynthetic process|up regulation of glycogen biosynthetic process|activation of glycogen biosynthetic process|positive regulation of glycogen biosynthesis|positive regulation of glycogen anabolism|stimulation of glycogen biosynthetic process|positive regulation of glycogen synthesis|positive regulation of glycogen formation http://purl.obolibrary.org/obo/GO_0045725 GO:0045726 biolink:BiologicalProcess positive regulation of integrin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. go-plus.json positive regulation of integrin anabolism|upregulation of integrin biosynthetic process|positive regulation of integrin synthesis|positive regulation of integrin formation|up regulation of integrin biosynthetic process|positive regulation of integrin biosynthesis|activation of integrin biosynthetic process|stimulation of integrin biosynthetic process|up-regulation of integrin biosynthetic process http://purl.obolibrary.org/obo/GO_0045726 GO:0045723 biolink:BiologicalProcess positive regulation of fatty acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. go-plus.json up regulation of fatty acid biosynthetic process|activation of fatty acid biosynthetic process|positive regulation of fatty acid biosynthesis|positive regulation of fatty acid anabolism|stimulation of fatty acid biosynthetic process|positive regulation of fatty acid synthesis|positive regulation of fatty acid formation|up-regulation of fatty acid biosynthetic process|upregulation of fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0045723 GO:0045724 biolink:BiologicalProcess positive regulation of cilium assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. go-plus.json up regulation of cilium assembly|activation of cilium assembly|stimulation of cilium assembly|up-regulation of cilium assembly|positive regulation of flagellum assembly|positive regulation of flagellum biogenesis|upregulation of cilium assembly http://purl.obolibrary.org/obo/GO_0045724 GO:0031135 biolink:BiologicalProcess negative regulation of conjugation Any process that decreases the rate of conjugation. go-plus.json down regulation of conjugation|downregulation of conjugation|down-regulation of conjugation|inhibition of conjugation http://purl.obolibrary.org/obo/GO_0031135 GO:0031136 biolink:BiologicalProcess positive regulation of conjugation Any process that increases the rate or frequency of conjugation. go-plus.json upregulation of conjugation|up regulation of conjugation|activation of conjugation|stimulation of conjugation|up-regulation of conjugation http://purl.obolibrary.org/obo/GO_0031136 GO:0031133 biolink:BiologicalProcess regulation of axon diameter Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0031133 GO:0031134 biolink:BiologicalProcess sister chromatid biorientation The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles. go-plus.json chromosome biorientation|sister kinetochore biorientation http://purl.obolibrary.org/obo/GO_0031134 GO:0031131 biolink:BiologicalProcess reception of an inductive signal The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change. go-plus.json http://purl.obolibrary.org/obo/GO_0031131 GO:0031132 biolink:MolecularActivity serine 3-dehydrogenase activity Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH. RHEA:21596|KEGG_REACTION:R06126|EC:1.1.1.276|Wikipedia:Serine_3-dehydrogenase|MetaCyc:RXN0-2201 go-plus.json L-serine:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0031132 GO:0031130 biolink:BiologicalProcess creation of an inductive signal The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter. go-plus.json http://purl.obolibrary.org/obo/GO_0031130 GO:0031128 biolink:BiologicalProcess developmental induction A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). go-plus.json http://purl.obolibrary.org/obo/GO_0031128 GO:0031129 biolink:BiologicalProcess inductive cell-cell signaling Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate. go-plus.json inductive cell-cell signalling http://purl.obolibrary.org/obo/GO_0031129 GO:0031126 biolink:BiologicalProcess sno(s)RNA 3'-end processing Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea. go-plus.json sno(s)RNA 3' end processing|sRNA 3'-end processing|snoRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0031126 GO:0031127 biolink:MolecularActivity alpha-(1,2)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage. go-plus.json alpha-1,2-fucosyltransferase activity|alpha-(1->2)-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0031127 GO:0045732 biolink:BiologicalProcess positive regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. go-plus.json activation of protein catabolic process|positive regulation of protein catabolism|stimulation of protein catabolic process|up-regulation of protein catabolic process|upregulation of protein catabolic process|positive regulation of protein degradation|positive regulation of protein breakdown|up regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0045732 GO:0006168 biolink:BiologicalProcess adenine salvage Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis. go-plus.json adenine salvage pathway|adenine, hypoxanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0006168 GO:0045733 biolink:BiologicalProcess acetate catabolic process The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid. go-plus.json acetate degradation|acetate breakdown|homoacetate catabolic process|acetate catabolism http://purl.obolibrary.org/obo/GO_0045733 GO:0006169 biolink:BiologicalProcess adenosine salvage Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis. go-plus.json adenine, hypoxanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0006169 GO:0006166 biolink:BiologicalProcess purine ribonucleoside salvage Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis. MetaCyc:P121-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0006166 GO:0045730 biolink:BiologicalProcess respiratory burst A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Wikipedia:Respiratory_burst go-plus.json oxidative burst|metabolic burst http://purl.obolibrary.org/obo/GO_0045730 GO:0006167 biolink:BiologicalProcess AMP biosynthetic process The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate. go-plus.json AMP synthesis|AMP formation|AMP biosynthesis|AMP anabolism http://purl.obolibrary.org/obo/GO_0006167 GO:0045731 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045731 GO:0006164 biolink:BiologicalProcess purine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. MetaCyc:DENOVOPURINE2-PWY go-plus.json purine nucleotide anabolism|purine nucleotide synthesis|purine nucleotide biosynthesis|purine nucleotide formation http://purl.obolibrary.org/obo/GO_0006164 GO:0006165 biolink:BiologicalProcess nucleoside diphosphate phosphorylation The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0006165 GO:0006162 biolink:BiologicalProcess obsolete purine/pyrimidine nucleoside diphosphate reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json purine/pyrimidine nucleoside diphosphate reduction http://purl.obolibrary.org/obo/GO_0006162 GO:0006163 biolink:BiologicalProcess purine nucleotide metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine nucleotide metabolism|purine metabolism|purine metabolic process http://purl.obolibrary.org/obo/GO_0006163 GO:0006171 biolink:BiologicalProcess cAMP biosynthetic process The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json cAMP anabolism|3',5' cAMP biosynthetic process|cAMP synthesis|3',5' cAMP biosynthesis|cAMP formation|cyclic AMP biosynthesis|cyclic AMP biosynthetic process|cAMP biosynthesis|adenosine 3',5'-cyclophosphate biosynthesis|adenosine 3',5'-cyclophosphate biosynthetic process|3',5'-cAMP biosynthetic process|3',5'-cAMP biosynthesis http://purl.obolibrary.org/obo/GO_0006171 GO:0006172 biolink:BiologicalProcess ADP biosynthetic process The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. go-plus.json ADP synthesis|ADP biosynthesis|ADP formation|ADP anabolism http://purl.obolibrary.org/obo/GO_0006172 GO:0045738 biolink:BiologicalProcess negative regulation of DNA repair Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair. go-plus.json down regulation of DNA repair|inhibition of DNA repair|down-regulation of DNA repair|downregulation of DNA repair http://purl.obolibrary.org/obo/GO_0045738 GO:0045739 biolink:BiologicalProcess positive regulation of DNA repair Any process that activates or increases the frequency, rate or extent of DNA repair. go-plus.json upregulation of DNA repair|stimulation of DNA repair|activation of DNA repair|up-regulation of DNA repair|up regulation of DNA repair http://purl.obolibrary.org/obo/GO_0045739 GO:0006170 biolink:BiologicalProcess dAMP biosynthetic process The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). go-plus.json dAMP anabolism|dAMP synthesis|dAMP formation|dAMP biosynthesis http://purl.obolibrary.org/obo/GO_0006170 GO:0045736 biolink:BiologicalProcess negative regulation of cyclin-dependent protein serine/threonine kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0045736 GO:0045737 biolink:BiologicalProcess positive regulation of cyclin-dependent protein serine/threonine kinase activity Any process that activates or increases the frequency, rate or extent of CDK activity. go-plus.json upregulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity|up-regulation of cyclin-dependent protein kinase activity|stimulation of cyclin-dependent protein kinase activity|activation of cyclin-dependent protein kinase activity|positive regulation of CDK activity|up regulation of cyclin-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_0045737 GO:0045734 biolink:BiologicalProcess regulation of acetate catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid. go-plus.json regulation of acetate catabolism|regulation of acetate degradation|regulation of acetate breakdown http://purl.obolibrary.org/obo/GO_0045734 GO:0045735 biolink:MolecularActivity nutrient reservoir activity Functions in the storage of nutritious substrates. go-plus.json storage protein|yolk protein|storage protein of fat body http://purl.obolibrary.org/obo/GO_0045735 goslim_pir GO:0031124 biolink:BiologicalProcess mRNA 3'-end processing Any process involved in forming the mature 3' end of an mRNA molecule. go-plus.json mRNA 3' end processing http://purl.obolibrary.org/obo/GO_0031124 GO:0031125 biolink:BiologicalProcess rRNA 3'-end processing Any process involved in forming the mature 3' end of an rRNA molecule. go-plus.json rRNA 3' end processing http://purl.obolibrary.org/obo/GO_0031125 GO:0031122 biolink:BiologicalProcess cytoplasmic microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. go-plus.json cytoplasmic microtubule organisation|cytoplasmic microtubule organization and biogenesis http://purl.obolibrary.org/obo/GO_0031122 GO:0031123 biolink:BiologicalProcess RNA 3'-end processing Any process involved in forming the mature 3' end of an RNA molecule. go-plus.json RNA 3' end processing http://purl.obolibrary.org/obo/GO_0031123 GO:0031120 biolink:BiologicalProcess snRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in an snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031120 GO:0031121 biolink:BiologicalProcess equatorial microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell. go-plus.json equatorial microtubule organisation|equatorial microtubule organization and biogenesis http://purl.obolibrary.org/obo/GO_0031121 GO:0021790 biolink:BiologicalProcess chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json negative chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme http://purl.obolibrary.org/obo/GO_0021790 GO:0021791 biolink:BiologicalProcess chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json positive chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme http://purl.obolibrary.org/obo/GO_0021791 GO:0031119 biolink:BiologicalProcess tRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in a tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031119 GO:0021792 biolink:BiologicalProcess chemoattraction of branchiomotor axon The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json positive chemotaxis of branchiomotor axon http://purl.obolibrary.org/obo/GO_0021792 GO:0021793 biolink:BiologicalProcess chemorepulsion of branchiomotor axon The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. go-plus.json negative chemotaxis of branchiomotor axon http://purl.obolibrary.org/obo/GO_0021793 GO:0031117 biolink:BiologicalProcess positive regulation of microtubule depolymerization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. go-plus.json upregulation of microtubule depolymerization|microtubule destabilization|stimulation of microtubule depolymerization|positive regulation of microtubule catastrophe|positive regulation of microtubule disassembly|up-regulation of microtubule depolymerization|activation of microtubule depolymerization|up regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031117 GO:0021794 biolink:BiologicalProcess thalamus development The process in which the thalamus changes over time, from its initial formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0021794 GO:0021795 biolink:BiologicalProcess cerebral cortex cell migration The orderly movement of cells from one site to another in the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021795 GO:0031118 biolink:BiologicalProcess rRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in an rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031118 GO:0031115 biolink:BiologicalProcess negative regulation of microtubule polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. go-plus.json inhibition of microtubule polymerization|down-regulation of microtubule polymerization|downregulation of microtubule polymerization|down regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031115 GO:0021796 biolink:BiologicalProcess cerebral cortex regionalization The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops. go-plus.json cerebral cortex arealization|cerebral cortex pattern formation|cerebral cortex pattern biosynthesis http://purl.obolibrary.org/obo/GO_0021796 GO:0031116 biolink:BiologicalProcess positive regulation of microtubule polymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization. go-plus.json upregulation of microtubule polymerization|stimulation of microtubule polymerization|up-regulation of microtubule polymerization|activation of microtubule polymerization|up regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031116 GO:0021797 biolink:BiologicalProcess forebrain anterior/posterior pattern specification The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain. go-plus.json forebrain anterior-posterior pattern specification http://purl.obolibrary.org/obo/GO_0021797 GO:0045743 biolink:BiologicalProcess positive regulation of fibroblast growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. go-plus.json positive regulation of FGF receptor signaling pathway|upregulation of fibroblast growth factor receptor signaling pathway|positive regulation of FGFR signaling pathway|up regulation of fibroblast growth factor receptor signaling pathway|activation of fibroblast growth factor receptor signaling pathway|stimulation of fibroblast growth factor receptor signaling pathway|positive regulation of FGF receptor signalling pathway|up-regulation of fibroblast growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0045743 GO:0006179 biolink:BiologicalProcess guanosine salvage Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis. go-plus.json guanine, xanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0006179 GO:0045744 biolink:BiologicalProcess negative regulation of G protein-coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. go-plus.json negative regulation of G protein coupled receptor protein signaling pathway|down regulation of G-protein coupled receptor protein signaling pathway|inhibition of G-protein coupled receptor protein signaling pathway|negative regulation of GPCR protein signalling pathway|negative regulation of G-protein coupled receptor protein signalling pathway|down-regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein-coupled receptor protein signalling pathway|negative regulation of GPCR protein signaling pathway|negative regulation of G protein coupled receptor protein signalling pathway|downregulation of G-protein coupled receptor protein signaling pathway http://purl.obolibrary.org/obo/GO_0045744 GO:0045741 biolink:BiologicalProcess positive regulation of epidermal growth factor-activated receptor activity Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity. go-plus.json upregulation of epidermal growth factor receptor activity|positive regulation of epidermal growth factor receptor activity|up regulation of epidermal growth factor receptor activity|positive regulation of EGFR activity|activation of epidermal growth factor receptor activity|stimulation of epidermal growth factor receptor activity|positive regulation of EGF receptor activity|up-regulation of epidermal growth factor receptor activity http://purl.obolibrary.org/obo/GO_0045741 GO:0006177 biolink:BiologicalProcess GMP biosynthetic process The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate. go-plus.json GMP biosynthesis|GMP anabolism|GMP synthesis|GMP formation http://purl.obolibrary.org/obo/GO_0006177 GO:0045742 biolink:BiologicalProcess positive regulation of epidermal growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. go-plus.json positive regulation of EGFR signaling pathway|up regulation of epidermal growth factor receptor signaling pathway|upregulation of epidermal growth factor receptor signaling pathway|stimulation of epidermal growth factor receptor signaling pathway|activation of epidermal growth factor receptor signaling pathway|up-regulation of epidermal growth factor receptor signaling pathway|positive regulation of EGF receptor signalling pathway|positive regulation of EGF receptor signaling pathway http://purl.obolibrary.org/obo/GO_0045742 GO:0006178 biolink:BiologicalProcess guanine salvage Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis. go-plus.json guanine, xanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0006178 GO:0006175 biolink:BiologicalProcess dATP biosynthetic process The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate). go-plus.json dATP biosynthesis|dATP anabolism|dATP synthesis|dATP formation http://purl.obolibrary.org/obo/GO_0006175 GO:0045740 biolink:BiologicalProcess positive regulation of DNA replication Any process that activates or increases the frequency, rate or extent of DNA replication. go-plus.json up regulation of DNA replication|activation of DNA replication|stimulation of DNA replication|up-regulation of DNA replication|upregulation of DNA replication http://purl.obolibrary.org/obo/GO_0045740 GO:0006176 biolink:BiologicalProcess dATP biosynthetic process from ADP The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate. go-plus.json dATP formation from ADP|dATP synthesis from ADP|dATP anabolism from ADP http://purl.obolibrary.org/obo/GO_0006176 GO:0006173 biolink:BiologicalProcess dADP biosynthetic process The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate). go-plus.json dADP biosynthesis|dADP anabolism|dADP synthesis|dADP formation http://purl.obolibrary.org/obo/GO_0006173 GO:0006174 biolink:BiologicalProcess dADP phosphorylation The process of introducing a phosphate group into dADP, deoxyadenosine diphosphate, to produce dATP. go-plus.json http://purl.obolibrary.org/obo/GO_0006174 GO:0006182 biolink:BiologicalProcess cGMP biosynthetic process The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate. go-plus.json cGMP biosynthesis|cGMP anabolism|cGMP synthesis|cGMP formation http://purl.obolibrary.org/obo/GO_0006182 GO:0006183 biolink:BiologicalProcess GTP biosynthetic process The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. go-plus.json GTP biosynthesis|GTP anabolism|GTP synthesis|GTP formation http://purl.obolibrary.org/obo/GO_0006183 GO:0006180 biolink:BiologicalProcess deoxyguanosine salvage Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0006180 GO:0045749 biolink:BiologicalProcess obsolete negative regulation of S phase of mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity. go-plus.json down regulation of S phase of mitotic cell cycle|downregulation of S phase of mitotic cell cycle|down-regulation of S phase of mitotic cell cycle|negative regulation of S phase of mitotic cell cycle|inhibition of S phase of mitotic cell cycle|negative regulation of S-phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045749 GO:0006181 biolink:BiologicalProcess dGMP biosynthetic process The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). go-plus.json dGMP biosynthesis|dGMP anabolism|dGMP synthesis|dGMP formation http://purl.obolibrary.org/obo/GO_0006181 GO:0045747 biolink:BiologicalProcess positive regulation of Notch signaling pathway Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway. go-plus.json up-regulation of Notch signaling pathway|positive regulation of N signalling pathway|upregulation of Notch signaling pathway|positive regulation of Notch signalling pathway|up regulation of Notch signaling pathway|activation of Notch signaling pathway|stimulation of Notch signaling pathway|positive regulation of N signaling pathway http://purl.obolibrary.org/obo/GO_0045747 GO:0045748 biolink:BiologicalProcess positive regulation of R8 cell spacing in compound eye Any process that activates or enforces the correct R8 cell spacing in a compound eye. go-plus.json upregulation of R8 spacing|stimulation of R8 spacing|positive regulation of R8 spacing|activation of R8 spacing|up-regulation of R8 spacing|up regulation of R8 spacing http://purl.obolibrary.org/obo/GO_0045748 GO:0045745 biolink:BiologicalProcess positive regulation of G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. go-plus.json positive regulation of GPCR protein signalling pathway|positive regulation of G-protein coupled receptor protein signalling pathway|upregulation of G-protein coupled receptor protein signaling pathway|positive regulation of G protein coupled receptor protein signaling pathway|stimulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein-coupled receptor protein signaling pathway|up-regulation of G-protein coupled receptor protein signaling pathway|activation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein-coupled receptor protein signalling pathway|positive regulation of G protein coupled receptor protein signalling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|up regulation of G-protein coupled receptor protein signaling pathway|positive regulation of GPCR protein signaling pathway http://purl.obolibrary.org/obo/GO_0045745 GO:0045746 biolink:BiologicalProcess negative regulation of Notch signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway. go-plus.json negative regulation of N signaling pathway|negative regulation of Notch signalling pathway|down regulation of Notch signaling pathway|downregulation of Notch signaling pathway|down-regulation of Notch signaling pathway|negative regulation of N signalling pathway|inhibition of Notch signaling pathway http://purl.obolibrary.org/obo/GO_0045746 GO:0021798 biolink:BiologicalProcess forebrain dorsal/ventral pattern formation The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain. go-plus.json forebrain dorsal-ventral pattern formation|forebrain dorsoventral pattern formation http://purl.obolibrary.org/obo/GO_0021798 GO:0031113 biolink:BiologicalProcess regulation of microtubule polymerization Any process that modulates the frequency, rate or extent of microtubule polymerization. go-plus.json http://purl.obolibrary.org/obo/GO_0031113 GO:0031114 biolink:BiologicalProcess regulation of microtubule depolymerization Any process that modulates the frequency, rate or extent of microtubule depolymerization. go-plus.json regulation of microtubule disassembly http://purl.obolibrary.org/obo/GO_0031114 GO:0021799 biolink:BiologicalProcess cerebral cortex radially oriented cell migration The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. go-plus.json http://purl.obolibrary.org/obo/GO_0021799 GO:0031111 biolink:BiologicalProcess negative regulation of microtubule polymerization or depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. go-plus.json downregulation of microtubule polymerization or depolymerization|down regulation of microtubule polymerization or depolymerization|inhibition of microtubule polymerization or depolymerization|down-regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0031111 GO:0031112 biolink:BiologicalProcess positive regulation of microtubule polymerization or depolymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. go-plus.json up regulation of microtubule polymerization or depolymerization|upregulation of microtubule polymerization or depolymerization|stimulation of microtubule polymerization or depolymerization|up-regulation of microtubule polymerization or depolymerization|activation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0031112 GO:0031110 biolink:BiologicalProcess regulation of microtubule polymerization or depolymerization Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0031110 CHEBI:46951 biolink:ChemicalSubstance 3-(2,3-dihydroxyphenyl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46951 chebi_ph7_3 CHEBI:22985 biolink:ChemicalSubstance calcium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_22985 CHEBI:46952 biolink:ChemicalSubstance oxazinane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46952 CHEBI:22986 biolink:ChemicalSubstance calcium ionophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_22986 CHEBI:46953 biolink:ChemicalSubstance alpha-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_46953 chebi_ph7_3 CHEBI:46954 biolink:ChemicalSubstance thiazinane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46954 CHEBI:22984 biolink:ChemicalSubstance calcium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_22984 chebi_ph7_3 CHEBI:46955 biolink:ChemicalSubstance anthracenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_46955 CHEBI:32304 biolink:ChemicalSubstance 2-cis,4-trans-xanthoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_32304 chebi_ph7_3 CHEBI:4917 biolink:ChemicalSubstance eugenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_4917 chebi_ph7_3 GO:0080076 biolink:MolecularActivity caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080076 GO:0080077 biolink:MolecularActivity trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080077 GO:0080078 biolink:MolecularActivity tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080078 GO:0080079 biolink:MolecularActivity cellobiose glucosidase activity Catalysis of the reaction: cellobiose + H2O = 2 D-glucose. MetaCyc:RXN-10773 go-plus.json cellobiose glucohydrolase activity http://purl.obolibrary.org/obo/GO_0080079 GO:0080072 biolink:MolecularActivity spermidine:sinapoyl CoA N-acyltransferase activity Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080072 GO:0080073 biolink:MolecularActivity spermidine:coumaroyl CoA N-acyltransferase activity Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080073 GO:0080074 biolink:MolecularActivity spermidine:caffeoyl CoA N-acyltransferase activity Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080074 GO:0080075 biolink:MolecularActivity spermidine:feruloyl CoA N-acyltransferase activity Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080075 GO:0080070 biolink:MolecularActivity 8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate. MetaCyc:RXNQT-4333 go-plus.json http://purl.obolibrary.org/obo/GO_0080070 CHEBI:4911 biolink:ChemicalSubstance etoposide go-plus.json http://purl.obolibrary.org/obo/CHEBI_4911 chebi_ph7_3 GO:0080071 biolink:MolecularActivity indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate. MetaCyc:RXN-1443 go-plus.json http://purl.obolibrary.org/obo/GO_0080071 CHEBI:46957 biolink:ChemicalSubstance 3-(2-hydroxyphenyl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46957 chebi_ph7_3 CHEBI:46959 biolink:ChemicalSubstance N-acylazetidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46959 CHEBI:22990 biolink:ChemicalSubstance camalexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22990 chebi_ph7_3 CHEBI:46940 biolink:ChemicalSubstance indanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_46940 CHEBI:46941 biolink:ChemicalSubstance oxane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46941 chebi_ph7_3 CHEBI:46942 biolink:ChemicalSubstance oxanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_46942 GO:0080069 biolink:MolecularActivity 7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate. MetaCyc:RXNQT-4332 go-plus.json http://purl.obolibrary.org/obo/GO_0080069 GO:0080065 biolink:BiologicalProcess 4-alpha-methyl-delta7-sterol oxidation A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O. go-plus.json 4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity http://purl.obolibrary.org/obo/GO_0080065 GO:0080066 biolink:MolecularActivity 3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate. MetaCyc:RXN-2209 go-plus.json http://purl.obolibrary.org/obo/GO_0080066 GO:0080067 biolink:MolecularActivity 4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate. MetaCyc:RXNQT-4329 go-plus.json http://purl.obolibrary.org/obo/GO_0080067 GO:0080068 biolink:MolecularActivity 5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate. MetaCyc:RXNQT-4330 go-plus.json http://purl.obolibrary.org/obo/GO_0080068 GO:0080061 biolink:MolecularActivity indole-3-acetonitrile nitrilase activity Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3. MetaCyc:RXN-1404|RHEA:45776|EC:3.5.5.1 go-plus.json http://purl.obolibrary.org/obo/GO_0080061 GO:0080062 biolink:MolecularActivity cytokinin 9-beta-glucosyltransferase activity Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event. KEGG_REACTION:R08369 go-plus.json http://purl.obolibrary.org/obo/GO_0080062 GO:0080063 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080063 GO:0080064 biolink:BiologicalProcess 4,4-dimethyl-9beta,19-cyclopropylsterol oxidation A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O. go-plus.json 4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity http://purl.obolibrary.org/obo/GO_0080064 UBERON:0003161 biolink:AnatomicalEntity dorsal ocellus A simple visual organ of insects[GO]. Two ocelli appear on the vertical and one on the frontal plate[FBbt]. The multi-tissue structure that is located on the top of the head, composed of the corneal lens, pigment cell, rhabdoms and synaptic plexus[HAO]. Two evolutionary distinct ocellus types exist [2]: dorsal ocelli (or simply 'ocelli'), found in most insects, and lateral ocelli (or stemmata), which are found in the larvae of some insect orders. They are structurally and functionally very different. Simple eyes of other animals, e.g. cnidarians may also be referred to as 'ocelli', but again the structure and anatomy of these eyes is quite distinct from those of the dorsal ocelli of insects[Wikipedia]. go-plus.json ocelli|ocellus|dorsal ocelli http://purl.obolibrary.org/obo/UBERON_0003161 NCBITaxon:9721 biolink:OrganismalEntity Cetacea go-plus.json whales & dolphins|whales, dolphins, and porpoises|cetaceans|whales|whale http://purl.obolibrary.org/obo/NCBITaxon_9721 NCBITaxon:9722 biolink:OrganismalEntity Odontoceti go-plus.json tooth whales http://purl.obolibrary.org/obo/NCBITaxon_9722 GO:0080060 biolink:BiologicalProcess integument development The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex. go-plus.json http://purl.obolibrary.org/obo/GO_0080060 CHEBI:22998 biolink:ChemicalSubstance canadine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22998 chebi_ph7_3 CHEBI:22961 biolink:ChemicalSubstance butenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_22961 GO:0080098 biolink:MolecularActivity L-tyrosine:pyruvate aminotransferase activity Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine. EC:2.6.1.58|MetaCyc:RXN3O-4157 go-plus.json http://purl.obolibrary.org/obo/GO_0080098 CHEBI:71938 biolink:ChemicalSubstance 9-ribosyl-trans-zeatin 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71938 GO:0080099 biolink:MolecularActivity L-methionine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate. go-plus.json L-methionine:alpha-ketoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0080099 GO:0080094 biolink:BiologicalProcess response to trehalose-6-phosphate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus. go-plus.json response to trehalose-6-phosphate stimulus http://purl.obolibrary.org/obo/GO_0080094 GO:0080095 biolink:MolecularActivity phosphatidylethanolamine-sterol O-acyltransferase activity Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine. go-plus.json http://purl.obolibrary.org/obo/GO_0080095 GO:0080096 biolink:MolecularActivity phosphatidate-sterol O-acyltransferase activity Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate. go-plus.json http://purl.obolibrary.org/obo/GO_0080096 GO:0080097 biolink:MolecularActivity L-tryptophan:pyruvate aminotransferase activity Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine. EC:2.6.1.99|RHEA:27586|MetaCyc:RXN-10139 go-plus.json http://purl.obolibrary.org/obo/GO_0080097 GO:0080090 biolink:BiologicalProcess regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0080090 GO:0080091 biolink:BiologicalProcess regulation of raffinose metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose. go-plus.json http://purl.obolibrary.org/obo/GO_0080091 GO:0080092 biolink:BiologicalProcess regulation of pollen tube growth Any process that modulates the frequency, rate or extent of pollen tube growth. go-plus.json http://purl.obolibrary.org/obo/GO_0080092 GO:0080093 biolink:BiologicalProcess regulation of photorespiration Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. go-plus.json http://purl.obolibrary.org/obo/GO_0080093 CHEBI:22967 biolink:ChemicalSubstance butyn-1-ols go-plus.json http://purl.obolibrary.org/obo/CHEBI_22967 CHEBI:22968 biolink:ChemicalSubstance butynal go-plus.json http://purl.obolibrary.org/obo/CHEBI_22968 CHEBI:22965 biolink:ChemicalSubstance butanamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_22965 CHEBI:46939 biolink:ChemicalSubstance indolyl carboxylate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_46939 CHEBI:22970 biolink:ChemicalSubstance butynediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22970 CHEBI:22975 biolink:ChemicalSubstance cadinane sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22975 CHEBI:46920 biolink:ChemicalSubstance N-methylpiperazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46920 CHEBI:71944 biolink:ChemicalSubstance aldehydic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71944 CHEBI:4903 biolink:ChemicalSubstance 17alpha-ethynylestradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_4903 chebi_ph7_3 CHEBI:71947 biolink:ChemicalSubstance tyrocidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71947 CHEBI:71948 biolink:ChemicalSubstance tyrocidine B go-plus.json http://purl.obolibrary.org/obo/CHEBI_71948 GO:0080087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080087 CHEBI:71949 biolink:ChemicalSubstance tyrocidine C go-plus.json http://purl.obolibrary.org/obo/CHEBI_71949 GO:0080088 biolink:BiologicalProcess spermidine hydroxycinnamate conjugate biosynthetic process The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates. go-plus.json http://purl.obolibrary.org/obo/GO_0080088 GO:0080089 biolink:MolecularActivity sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0080089 GO:0080083 biolink:MolecularActivity beta-gentiobiose beta-glucosidase activity Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose. go-plus.json http://purl.obolibrary.org/obo/GO_0080083 UBERON:0003142 biolink:AnatomicalEntity prepupa An organism at the prepupal stage. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation go-plus.json http://purl.obolibrary.org/obo/UBERON_0003142 GO:0080084 biolink:MolecularActivity 5S rDNA binding Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists. go-plus.json http://purl.obolibrary.org/obo/GO_0080084 UBERON:0003143 biolink:AnatomicalEntity pupa An organism at the pupal stage. A life cycle stage of holometabolous insects in which the organism is a pupa and starts with the larval-pupal apolysis and ends with pupal-adult apolysis. go-plus.json pupae|aurelia|chrysalis|chrysalides http://purl.obolibrary.org/obo/UBERON_0003143 GO:0080085 biolink:CellularComponent signal recognition particle, chloroplast targeting A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0080085 GO:0080086 biolink:BiologicalProcess stamen filament development The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen. go-plus.json filament development http://purl.obolibrary.org/obo/GO_0080086 GO:0080080 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080080 GO:0080081 biolink:MolecularActivity 4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside. go-plus.json http://purl.obolibrary.org/obo/GO_0080081 GO:0080082 biolink:MolecularActivity esculin beta-glucosidase activity Catalysis of the hydrolysis of glucosidic link in esculin. go-plus.json http://purl.obolibrary.org/obo/GO_0080082 CHEBI:22976 biolink:ChemicalSubstance cadinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_22976 CHEBI:71950 biolink:ChemicalSubstance tyrocidine D go-plus.json http://purl.obolibrary.org/obo/CHEBI_71950 CHEBI:46911 biolink:ChemicalSubstance L-ornithinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46911 chebi_ph7_3 CHEBI:71959 biolink:ChemicalSubstance 3-amino-5-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71959 chebi_ph7_3 CHEBI:46912 biolink:ChemicalSubstance ornithinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46912 chebi_ph7_3 CHEBI:46913 biolink:ChemicalSubstance ornithinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46913 CHEBI:46914 biolink:ChemicalSubstance L-ornithinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46914 CHEBI:22944 biolink:ChemicalSubstance butanediols go-plus.json http://purl.obolibrary.org/obo/CHEBI_22944 CHEBI:46915 biolink:ChemicalSubstance sarcosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46915 CHEBI:71963 biolink:ChemicalSubstance 5-amino-5-deoxy-3-dehydroshikimic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71963 chebi_ph7_3 CHEBI:71964 biolink:ChemicalSubstance UDP-alpha-D-kanosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71964 chebi_ph7_3 CHEBI:71965 biolink:ChemicalSubstance UDP-3-keto-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71965 chebi_ph7_3 CHEBI:22950 biolink:ChemicalSubstance butan-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22950 CHEBI:46900 biolink:ChemicalSubstance cholesteryl octadec-9-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46900 chebi_ph7_3 CHEBI:22951 biolink:ChemicalSubstance butanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_22951 CHEBI:71968 biolink:ChemicalSubstance hydroxyflavonoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71968 GO:0031094 biolink:CellularComponent platelet dense tubular network A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin. go-plus.json http://purl.obolibrary.org/obo/GO_0031094 goslim_pir GO:0031095 biolink:CellularComponent platelet dense tubular network membrane The lipid bilayer surrounding the platelet dense tubular network. go-plus.json http://purl.obolibrary.org/obo/GO_0031095 GO:0031092 biolink:CellularComponent platelet alpha granule membrane The lipid bilayer surrounding the platelet alpha granule. go-plus.json platelet alpha-granule membrane http://purl.obolibrary.org/obo/GO_0031092 GO:0031093 biolink:CellularComponent platelet alpha granule lumen The volume enclosed by the membrane of the platelet alpha granule. go-plus.json platelet alpha-granule lumen http://purl.obolibrary.org/obo/GO_0031093 GO:0031090 biolink:CellularComponent organelle membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. NIF_Subcellular:sao830981606 go-plus.json intracellular membrane http://purl.obolibrary.org/obo/GO_0031090 GO:0031091 biolink:CellularComponent platelet alpha granule A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG). Wikipedia:Platelet_alpha-granule go-plus.json platelet alpha-granule http://purl.obolibrary.org/obo/GO_0031091 CHEBI:46903 biolink:ChemicalSubstance cholesteryl octadeca-9,12-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46903 chebi_ph7_3 CHEBI:22954 biolink:ChemicalSubstance butanoyl-CoAs go-plus.json http://purl.obolibrary.org/obo/CHEBI_22954 CHEBI:46904 biolink:ChemicalSubstance oxalate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46904 GO:0031098 biolink:BiologicalProcess stress-activated protein kinase signaling cascade A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals. go-plus.json JNK signaling pathway|SAPK signaling pathway|stress-activated protein kinase signaling pathway|JNK signalling pathway|stress-activated protein kinase signalling pathway|SAPK signalling pathway http://purl.obolibrary.org/obo/GO_0031098 CHEBI:46905 biolink:ChemicalSubstance (R)-pantothenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46905 GO:0031099 biolink:BiologicalProcess regeneration The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). Wikipedia:Regeneration_(biology) go-plus.json http://purl.obolibrary.org/obo/GO_0031099 GO:0031096 biolink:CellularComponent platelet dense tubular network lumen The volume enclosed by the membranes of the platelet dense tubular network. go-plus.json http://purl.obolibrary.org/obo/GO_0031096 CHEBI:22958 biolink:ChemicalSubstance butenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22958 GO:0031097 biolink:CellularComponent medial cortex A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation. go-plus.json medial ring http://purl.obolibrary.org/obo/GO_0031097 CHEBI:22959 biolink:ChemicalSubstance butenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22959 GO:0031083 biolink:CellularComponent BLOC-1 complex A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0031083 GO:0031084 biolink:CellularComponent BLOC-2 complex A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru. go-plus.json http://purl.obolibrary.org/obo/GO_0031084 GO:0031081 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031081 CHEBI:22929 biolink:ChemicalSubstance bromoalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_22929 GO:0031082 biolink:CellularComponent BLOC complex Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex. go-plus.json BLOC-1 related complex http://purl.obolibrary.org/obo/GO_0031082 goslim_pir GO:0031080 biolink:CellularComponent nuclear pore outer ring A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). go-plus.json Nup107-160 complex|Nup84 complex|Nup107-120 complex http://purl.obolibrary.org/obo/GO_0031080 UBERON:0003194 biolink:AnatomicalEntity imaginal disc-derived wing vein go-plus.json http://purl.obolibrary.org/obo/UBERON_0003194 GO:0031089 biolink:CellularComponent platelet dense granule lumen The volume enclosed by the membrane of the platelet dense granule. go-plus.json http://purl.obolibrary.org/obo/GO_0031089 CHEBI:22921 biolink:ChemicalSubstance brassinosteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22921 CHEBI:22927 biolink:ChemicalSubstance bromine atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_22927 chebi_ph7_3 GO:0031087 biolink:BiologicalProcess deadenylation-independent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening. go-plus.json deadenylation-independent decapping of nuclear mRNA|deadenylylation-independent decapping http://purl.obolibrary.org/obo/GO_0031087 CHEBI:22928 biolink:ChemicalSubstance bromine molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_22928 GO:0031088 biolink:CellularComponent platelet dense granule membrane The lipid bilayer surrounding the platelet dense granule. go-plus.json http://purl.obolibrary.org/obo/GO_0031088 GO:0031085 biolink:CellularComponent BLOC-3 complex A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0031085 GO:0031086 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, deadenylation-independent decay A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability. go-plus.json deadenylylation-independent mRNA decay|nuclear mRNA catabolic process, deadenylation-independent decay|mRNA catabolic process, deadenylation-independent|mRNA catabolism, deadenylation-independent|mRNA catabolism, deadenylation-independent decay|deadenylation-independent mRNA decay|mRNA breakdown, deadenylation-independent decay|mRNA degradation, deadenylation-independent decay|mRNA catabolic process, deadenylylation-independent|mRNA catabolism, deadenylylation-independent http://purl.obolibrary.org/obo/GO_0031086 CHEBI:22926 biolink:ChemicalSubstance bromohydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_22926 CHEBI:71981 biolink:ChemicalSubstance beta-D-glucosylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71981 CHEBI:71982 biolink:ChemicalSubstance C20 sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71982 CHEBI:71983 biolink:ChemicalSubstance C20 sphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71983 chebi_ph7_3 CHEBI:71984 biolink:ChemicalSubstance C20 dihydroceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71984 chebi_ph7_3 CHEBI:71985 biolink:ChemicalSubstance C20 phytoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71985 chebi_ph7_3 CHEBI:22930 biolink:ChemicalSubstance bromoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22930 CHEBI:81308 biolink:ChemicalSubstance allocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81308 CHEBI:71986 biolink:ChemicalSubstance C20 ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71986 chebi_ph7_3 CHEBI:71989 biolink:ChemicalSubstance ortho ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_71989 chebi_ph7_3 GO:0031072 biolink:MolecularActivity heat shock protein binding Binding to a heat shock protein, a protein synthesized or activated in response to heat shock. go-plus.json http://purl.obolibrary.org/obo/GO_0031072 GO:0031073 biolink:MolecularActivity cholesterol 26-hydroxylase activity Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol. go-plus.json http://purl.obolibrary.org/obo/GO_0031073 GO:0031070 biolink:BiologicalProcess intronic snoRNA processing The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0031070 GO:0031071 biolink:MolecularActivity cysteine desulfurase activity Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine. EC:2.8.1.7|RHEA:43892|Reactome:R-HSA-1362408|Reactome:R-HSA-947514 go-plus.json SufS|NIFS|IscS|cysteine desulfurylase activity|L-cysteine:enzyme cysteine sulfurtransferase activity http://purl.obolibrary.org/obo/GO_0031071 GO:0031078 biolink:MolecularActivity histone deacetylase activity (H3-K14 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031078 GO:0031079 biolink:MolecularActivity obsolete picornain 3C activity OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly. go-plus.json foot-and-mouth protease 3C activity|poliovirus proteinase 3C|3C protease activity|rhinovirus proteinase 3C|foot-and-mouth-disease virus proteinase 3C|protease 3C|picornain 3C activity|tomato ringspot nepovirus 3C-related protease|hepatitis A virus 3C proteinase activity|rhinovirus protease 3C activity|poliovirus protease 3C activity|cysteine proteinase 3C|picornavirus endopeptidase 3C activity|coxsackievirus 3C proteinase activity|3C proteinase activity http://purl.obolibrary.org/obo/GO_0031079 CHEBI:22933 biolink:ChemicalSubstance bromophenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22933 GO:0031076 biolink:BiologicalProcess embryonic camera-type eye development The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. go-plus.json embryonic eye development http://purl.obolibrary.org/obo/GO_0031076 GO:0031077 biolink:BiologicalProcess post-embryonic camera-type eye development The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. go-plus.json post-embryonic camera-style eye development http://purl.obolibrary.org/obo/GO_0031077 CHEBI:22939 biolink:ChemicalSubstance butanals go-plus.json http://purl.obolibrary.org/obo/CHEBI_22939 GO:0031074 biolink:CellularComponent nucleocytoplasmic transport complex Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores. go-plus.json nucleocytoplasmic shuttling complex http://purl.obolibrary.org/obo/GO_0031074 gocheck_do_not_annotate|goslim_pir GO:0031075 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031075 CHEBI:71980 biolink:ChemicalSubstance N-retinylidene-N-retinylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71980 chebi_ph7_3 GO:0070670 biolink:BiologicalProcess response to interleukin-4 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus. go-plus.json response to IL-4 http://purl.obolibrary.org/obo/GO_0070670 NCBITaxon:9789 biolink:OrganismalEntity Equus go-plus.json Equus http://purl.obolibrary.org/obo/NCBITaxon_9789 GO:0021707 biolink:BiologicalProcess cerebellar granule cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021707 GO:0021708 biolink:BiologicalProcess Lugaro cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021708 GO:0055030 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055030 GO:0021709 biolink:BiologicalProcess cerebellar basket cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021709 CHEBI:32387 biolink:ChemicalSubstance alpha-linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32387 chebi_ph7_3 GO:0055031 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055031 NCBITaxon:9796 biolink:OrganismalEntity Equus caballus go-plus.json Equus przewalskii forma caballus|Equus przewalskii f. caballus|horse|domestic horse|equine http://purl.obolibrary.org/obo/NCBITaxon_9796 CHEBI:32389 biolink:ChemicalSubstance all-cis-octadeca-6,9,12,15-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32389 GO:0070679 biolink:MolecularActivity inositol 1,4,5 trisphosphate binding Binding to inositol 1,4,5 trisphosphate. go-plus.json IP3 binding|InsP3 binding http://purl.obolibrary.org/obo/GO_0070679 CHEBI:4999 biolink:ChemicalSubstance fenchone go-plus.json http://purl.obolibrary.org/obo/CHEBI_4999 chebi_ph7_3 GO:0055036 biolink:CellularComponent virion membrane The lipid bilayer surrounding a virion. go-plus.json http://purl.obolibrary.org/obo/GO_0055036 goslim_chembl GO:0070677 biolink:MolecularActivity rRNA (cytosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0070677 GO:0055037 biolink:CellularComponent recycling endosome An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane. go-plus.json endosomal recycling compartment|endosome recycling compartment|ERC http://purl.obolibrary.org/obo/GO_0055037 GO:0021700 biolink:BiologicalProcess developmental maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0021700 goslim_generic|goslim_chembl GO:0070678 biolink:MolecularActivity preprotein binding Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing. go-plus.json unprocessed protein binding http://purl.obolibrary.org/obo/GO_0070678 GO:0055038 biolink:CellularComponent recycling endosome membrane The lipid bilayer surrounding a recycling endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0055038 GO:0070675 biolink:MolecularActivity hypoxanthine oxidase activity Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2. go-plus.json Schardinger enzyme activity|hypoxanthine:O2 oxidoreductase activity|hypoxanthine:oxygen oxidoreductase activity|hypoxanthine-xanthine oxidase activity|xanthine oxidoreductase activity|hypoxanthine:O(2) oxidoreductase activity|schardinger enzyme http://purl.obolibrary.org/obo/GO_0070675 GO:0021701 biolink:BiologicalProcess cerebellar Golgi cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021701 GO:0070676 biolink:BiologicalProcess intralumenal vesicle formation The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome. go-plus.json endosome membrane budding http://purl.obolibrary.org/obo/GO_0070676 GO:0055039 biolink:CellularComponent trichocyst A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft. Wikipedia:Trichocyst go-plus.json http://purl.obolibrary.org/obo/GO_0055039 GO:0021702 biolink:BiologicalProcess cerebellar Purkinje cell differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. go-plus.json http://purl.obolibrary.org/obo/GO_0021702 GO:0070673 biolink:BiologicalProcess response to interleukin-18 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus. go-plus.json response to IL-18 http://purl.obolibrary.org/obo/GO_0070673 GO:0021703 biolink:BiologicalProcess locus ceruleus development The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. go-plus.json locus caeruleus development|locus coeruleus development http://purl.obolibrary.org/obo/GO_0021703 GO:0055032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055032 GO:0070674 biolink:MolecularActivity hypoxanthine dehydrogenase activity Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+. go-plus.json NAD-hypoxanthine dehydrogenase activity|hypoxanthine/NAD(+) oxidoreductase activity|hypoxanthine:NAD+ oxidoreductase activity|hypoxanthine-NAD oxidoreductase activity|hypoxanthine/NAD+ oxidoreductase activity|hypoxanthine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0070674 GO:0021704 biolink:BiologicalProcess locus ceruleus morphogenesis The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. go-plus.json http://purl.obolibrary.org/obo/GO_0021704 GO:0055033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055033 CHEBI:32381 biolink:ChemicalSubstance dec-9-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32381 CHEBI:32382 biolink:ChemicalSubstance (R)-mandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32382 chebi_ph7_3 GO:0021705 biolink:BiologicalProcess locus ceruleus formation The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. go-plus.json http://purl.obolibrary.org/obo/GO_0021705 GO:0055034 biolink:BiologicalProcess Bolwig's organ development The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain. go-plus.json http://purl.obolibrary.org/obo/GO_0055034 GO:0070671 biolink:BiologicalProcess response to interleukin-12 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus. go-plus.json response to IL-12 http://purl.obolibrary.org/obo/GO_0070671 GO:0055035 biolink:CellularComponent plastid thylakoid membrane The lipid bilayer membrane of any thylakoid within a plastid. go-plus.json http://purl.obolibrary.org/obo/GO_0055035 CHEBI:32383 biolink:ChemicalSubstance 6-hydroxyhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32383 chebi_ph7_3 GO:0021706 biolink:BiologicalProcess locus ceruleus maturation A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. go-plus.json http://purl.obolibrary.org/obo/GO_0021706 GO:0070672 biolink:BiologicalProcess response to interleukin-15 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus. go-plus.json response to IL-15 http://purl.obolibrary.org/obo/GO_0070672 CHEBI:32395 biolink:ChemicalSubstance arachidonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32395 chebi_ph7_3 CHEBI:32396 biolink:ChemicalSubstance 6-aminohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32396 GO:0055040 biolink:CellularComponent periplasmic flagellum Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella. go-plus.json http://purl.obolibrary.org/obo/GO_0055040 GO:0055041 biolink:MolecularActivity cyclopentanol dehydrogenase activity Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH. EC:1.1.1.163|RHEA:11728|KEGG_REACTION:R02553|MetaCyc:CYCLOPENTANOL-DEHYDROGENASE-RXN go-plus.json cyclopentanol:NADP+ oxidoreductase activity|cyclopentanol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0055041 CHEBI:32398 biolink:ChemicalSubstance D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32398 GO:0055042 biolink:MolecularActivity 5-valerolactone hydrolase activity Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate. go-plus.json http://purl.obolibrary.org/obo/GO_0055042 GO:0070668 biolink:BiologicalProcess positive regulation of mast cell proliferation Any process that activates or increases the rate or extent of mast cell proliferation. go-plus.json up regulation of mast cell proliferation|activation of mast cell proliferation|stimulation of mast cell proliferation|up-regulation of mast cell proliferation|upregulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070668 GO:0070669 biolink:BiologicalProcess response to interleukin-2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus. go-plus.json response to IL-2 http://purl.obolibrary.org/obo/GO_0070669 GO:0070666 biolink:BiologicalProcess regulation of mast cell proliferation Any process that modulates the frequency, rate or extent of mast cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0070666 GO:0055047 biolink:BiologicalProcess generative cell mitosis The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells. go-plus.json http://purl.obolibrary.org/obo/GO_0055047 GO:0070667 biolink:BiologicalProcess negative regulation of mast cell proliferation Any process that stops, prevents or reduces the rate or extent of mast cell proliferation. go-plus.json downregulation of mast cell proliferation|down-regulation of mast cell proliferation|inhibition of mast cell proliferation|down regulation of mast cell proliferation http://purl.obolibrary.org/obo/GO_0070667 GO:0055048 biolink:BiologicalProcess anastral spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0055048 GO:0070664 biolink:BiologicalProcess negative regulation of leukocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. go-plus.json down regulation of leukocyte proliferation|downregulation of leukocyte proliferation|down-regulation of leukocyte proliferation|inhibition of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0070664 GO:0055049 biolink:BiologicalProcess astral spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0055049 GO:0070665 biolink:BiologicalProcess positive regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. go-plus.json upregulation of leukocyte proliferation|up regulation of leukocyte proliferation|activation of leukocyte proliferation|stimulation of leukocyte proliferation|up-regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0070665 GO:0070662 biolink:BiologicalProcess mast cell proliferation The expansion of a mast cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0070662 CHEBI:32391 biolink:ChemicalSubstance gamma-linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32391 chebi_ph7_3 GO:0055043 biolink:MolecularActivity 5-oxovalerate dehydrogenase activity Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+. go-plus.json http://purl.obolibrary.org/obo/GO_0055043 GO:0070663 biolink:BiologicalProcess regulation of leukocyte proliferation Any process that modulates the frequency, rate or extent of leukocyte proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0070663 GO:0055044 biolink:CellularComponent symplast The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata. Wikipedia:Symplast go-plus.json http://purl.obolibrary.org/obo/GO_0055044 goslim_pir CHEBI:32392 biolink:ChemicalSubstance (15Z)-tetracosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32392 chebi_ph7_3 GO:0070660 biolink:BiologicalProcess inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury. go-plus.json http://purl.obolibrary.org/obo/GO_0070660 GO:0055045 biolink:BiologicalProcess antipodal cell degeneration The process in which the antipodal cells undergo programmed cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0055045 CHEBI:32393 biolink:ChemicalSubstance erucate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32393 chebi_ph7_3 GO:0055046 biolink:BiologicalProcess microgametogenesis The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure. Wikipedia:Microgametogenesis go-plus.json pollen development from the microspore http://purl.obolibrary.org/obo/GO_0055046 GO:0070661 biolink:BiologicalProcess leukocyte proliferation The expansion of a leukocyte population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0070661 GO:0070691 biolink:CellularComponent P-TEFb complex A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T. go-plus.json Sgv1/Bur2 complex|dimeric positive transcription elongation factor complex b|cyclin-dependent kinase 9 (Cdk9)-cyclin T1 complex|Bur1/Bur2 complex|cyclin-dependent kinase 9 (Cdk9)-cyclin T2 complex http://purl.obolibrary.org/obo/GO_0070691 GO:0070692 biolink:CellularComponent CTDK-1 complex A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638). go-plus.json trimeric positive transcription elongation factor complex b|Ctk complex|CTDK-I complex|C-terminal domain kinase I complex http://purl.obolibrary.org/obo/GO_0070692 GO:0070690 biolink:BiologicalProcess L-threonine catabolic process to acetyl-CoA The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA. MetaCyc:PWY-5436 go-plus.json L-threonine degradation to acetyl-CoA|L-threonine breakdown to acetyl-CoA|L-threonine catabolism to acetyl-CoA|threonine catabolic process to acetyl-CoA http://purl.obolibrary.org/obo/GO_0070690 GO:0080018 biolink:MolecularActivity anthocyanin 5-O-glucosyltransferase activity Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP. go-plus.json http://purl.obolibrary.org/obo/GO_0080018 GO:0080019 biolink:MolecularActivity fatty-acyl-CoA reductase (alcohol-forming) activity Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA. go-plus.json fatty acyl-CoA reductase (alcohol-forming) activity|fatty acyl CoA reductase (alcohol-forming) activity http://purl.obolibrary.org/obo/GO_0080019 GO:0080014 biolink:MolecularActivity thalianol hydroxylase activity Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X. EC:1.14.13.-|MetaCyc:RXN-9631 go-plus.json http://purl.obolibrary.org/obo/GO_0080014 GO:0080015 biolink:MolecularActivity sabinene synthase activity Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate. MetaCyc:RXN-5103|EC:4.2.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0080015 GO:0080016 biolink:MolecularActivity (-)-E-beta-caryophyllene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate. RHEA:28294|MetaCyc:RXN-8414|EC:4.2.3.57 go-plus.json http://purl.obolibrary.org/obo/GO_0080016 GO:0080017 biolink:MolecularActivity alpha-humulene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate. MetaCyc:RXN-8415|RHEA:31895|EC:4.2.3.104 go-plus.json http://purl.obolibrary.org/obo/GO_0080017 GO:0080010 biolink:BiologicalProcess obsolete regulation of oxygen and reactive oxygen species metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). go-plus.json regulation of oxygen and reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0080010 GO:0080011 biolink:MolecularActivity baruol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol. RHEA:31987|MetaCyc:RXN-9685|EC:5.4.99.57 go-plus.json http://purl.obolibrary.org/obo/GO_0080011 GO:0080012 biolink:MolecularActivity trihydroxyferuloyl spermidine O-methyltransferase activity Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-11263 go-plus.json N1,N5,N10-tris-(5-hydroxyferuloyl)spermidine O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0080012 GO:0080013 biolink:MolecularActivity (E,E)-geranyllinalool synthase activity Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate. MetaCyc:RXN-10441|RHEA:38155 go-plus.json http://purl.obolibrary.org/obo/GO_0080013 GO:0055050 biolink:BiologicalProcess astral spindle assembly involved in male meiosis The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0055050 CHEBI:32362 biolink:ChemicalSubstance heptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32362 chebi_ph7_3 GO:0055051 biolink:CellularComponent ATP-binding cassette (ABC) transporter complex, integrated substrate binding A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0055051 CHEBI:32364 biolink:ChemicalSubstance 3-dehydroquinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32364 chebi_ph7_3 GO:0055052 biolink:CellularComponent ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0055052 GO:0055053 biolink:MolecularActivity mannose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+. go-plus.json mannose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0055053 CHEBI:32365 biolink:ChemicalSubstance heptadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32365 CHEBI:32366 biolink:ChemicalSubstance margarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32366 chebi_ph7_3 CHEBI:32368 biolink:ChemicalSubstance undecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32368 CHEBI:32369 biolink:ChemicalSubstance undecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32369 chebi_ph7_3 GO:0055058 biolink:BiologicalProcess symmetric neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0055058 GO:0070699 biolink:MolecularActivity type II activin receptor binding Binding to a type II activin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070699 GO:0055059 biolink:BiologicalProcess asymmetric neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. go-plus.json http://purl.obolibrary.org/obo/GO_0055059 GO:0070697 biolink:MolecularActivity activin receptor binding Binding to an activin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070697 GO:0070698 biolink:MolecularActivity type I activin receptor binding Binding to a type I activin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070698 GO:0070695 biolink:CellularComponent FHF complex A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). go-plus.json http://purl.obolibrary.org/obo/GO_0070695 GO:0055054 biolink:MolecularActivity fructose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+. go-plus.json fructose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0055054 GO:0070696 biolink:MolecularActivity transmembrane receptor protein serine/threonine kinase binding Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0070696 GO:0055055 biolink:MolecularActivity D-glucose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose. go-plus.json D-glucose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0055055 GO:0070693 biolink:CellularComponent P-TEFb-cap methyltransferase complex A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase. go-plus.json P-TEFb-Pcm1 complex|Cdk9-Pcm1 complex http://purl.obolibrary.org/obo/GO_0070693 GO:0055056 biolink:MolecularActivity D-glucose transmembrane transporter activity Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other. Reactome:R-HSA-8981574|Reactome:R-HSA-8981564|Reactome:R-HSA-5339524|Reactome:R-HSA-8981570|Reactome:R-HSA-429094|Reactome:R-HSA-5632871|Reactome:R-HSA-5632804|Reactome:R-HSA-450095|Reactome:R-HSA-8981553 go-plus.json http://purl.obolibrary.org/obo/GO_0055056 CHEBI:32360 biolink:ChemicalSubstance icosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32360 chebi_ph7_3 GO:0070694 biolink:MolecularActivity deoxyribonucleoside 5'-monophosphate N-glycosidase activity Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base. Reactome:R-HSA-8953339 go-plus.json deoxynucleoside 5'-monophosphate N-glycosidase activity http://purl.obolibrary.org/obo/GO_0070694 GO:0055057 biolink:BiologicalProcess neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. go-plus.json neuroblast cell division http://purl.obolibrary.org/obo/GO_0055057 CHEBI:32361 biolink:ChemicalSubstance nonanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32361 chebi_ph7_3 GO:0070680 biolink:BiologicalProcess asparaginyl-tRNAAsn biosynthesis via transamidation A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase. MetaCyc:PWY490-4 go-plus.json http://purl.obolibrary.org/obo/GO_0070680 GO:0070681 biolink:BiologicalProcess glutaminyl-tRNAGln biosynthesis via transamidation A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase. MetaCyc:PWY-5921 go-plus.json http://purl.obolibrary.org/obo/GO_0070681 GO:0080007 biolink:MolecularActivity S-nitrosoglutathione reductase activity Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+. MetaCyc:RXN-10742 go-plus.json http://purl.obolibrary.org/obo/GO_0080007 GO:0080008 biolink:CellularComponent Cul4-RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. go-plus.json http://purl.obolibrary.org/obo/GO_0080008 GO:0080009 biolink:BiologicalProcess mRNA methylation The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080009 GO:0080003 biolink:BiologicalProcess thalianol metabolic process The chemical reactions and pathways involving the triterpene thalianol. go-plus.json thalianol metabolism http://purl.obolibrary.org/obo/GO_0080003 GO:0080004 biolink:MolecularActivity thalian-diol desaturase activity Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15. EC:1.14.21.-|MetaCyc:RXN-9637 go-plus.json http://purl.obolibrary.org/obo/GO_0080004 GO:0080005 biolink:BiologicalProcess photosystem stoichiometry adjustment Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0080005 GO:0080006 biolink:BiologicalProcess internode patterning Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached. go-plus.json http://purl.obolibrary.org/obo/GO_0080006 GO:0080001 biolink:BiologicalProcess mucilage extrusion from seed coat The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat. go-plus.json mucilage release from seed coat|secretion of mucilage from seed coat http://purl.obolibrary.org/obo/GO_0080001 GO:0080002 biolink:MolecularActivity UDP-glucose:4-aminobenzoate acylglucosyltransferase activity Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP. MetaCyc:RXN-6142 go-plus.json UDP-glucose:p-aminobenzoate acylglucosyltransferase activity|UDP-glucose:pABA acylglucosyltransferase activity|UDP-glucose:p-aminobenzoate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0080002 GO:0055061 biolink:BiologicalProcess obsolete di-, tri-valent inorganic anion homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions within an organism or cell. go-plus.json di-, tri-valent inorganic anion homeostasis http://purl.obolibrary.org/obo/GO_0055061 CHEBI:32373 biolink:ChemicalSubstance 4-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32373 chebi_ph7_3 CHEBI:4986 biolink:ChemicalSubstance fatty acid methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_4986 chebi_ph7_3 GO:0055062 biolink:BiologicalProcess phosphate ion homeostasis Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055062 CHEBI:32374 biolink:ChemicalSubstance trans-4-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32374 GO:0055063 biolink:BiologicalProcess sulfate ion homeostasis Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell. go-plus.json sulphate ion homeostasis|sulfate homeostasis http://purl.obolibrary.org/obo/GO_0055063 CHEBI:32375 biolink:ChemicalSubstance petroselinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32375 chebi_ph7_3 GO:0055064 biolink:BiologicalProcess chloride ion homeostasis Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055064 NCBITaxon:9787 biolink:OrganismalEntity Perissodactyla go-plus.json odd-toed ungulates|odd-toed ungulates http://purl.obolibrary.org/obo/NCBITaxon_9787 CHEBI:32379 biolink:ChemicalSubstance cis,cis-muconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32379 chebi_ph7_3 NCBITaxon:9788 biolink:OrganismalEntity Equidae go-plus.json horses http://purl.obolibrary.org/obo/NCBITaxon_9788 GO:0055060 biolink:BiologicalProcess asymmetric neuroblast division resulting in ganglion mother cell formation Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055060 GO:0070688 biolink:CellularComponent obsolete MLL5-L complex OBSOLETE. A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0070688 GO:0055069 biolink:BiologicalProcess zinc ion homeostasis Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell. go-plus.json zinc homeostasis http://purl.obolibrary.org/obo/GO_0055069 GO:0070689 biolink:BiologicalProcess L-threonine catabolic process to propionate The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate. MetaCyc:PWY-5437 go-plus.json L-threonine degradation to propionate|L-threonine breakdown to propionate|L-threonine catabolism to propionate|threonine catabolic process to propionate http://purl.obolibrary.org/obo/GO_0070689 GO:0070686 biolink:CellularComponent macropinocytic cup membrane The portion of the plasma membrane surrounding a macropinocytic cup. go-plus.json crown membrane http://purl.obolibrary.org/obo/GO_0070686 GO:0070687 biolink:CellularComponent macropinocytic cup cytoskeleton The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup. go-plus.json crown cytoskeleton http://purl.obolibrary.org/obo/GO_0070687 GO:0070684 biolink:BiologicalProcess seminal clot liquefaction The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa. go-plus.json semen liquefaction http://purl.obolibrary.org/obo/GO_0070684 GO:0055065 biolink:BiologicalProcess metal ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055065 goslim_pombe GO:0055066 biolink:BiologicalProcess obsolete di-, tri-valent inorganic cation homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations within an organism or cell. go-plus.json di-, tri-valent inorganic cation homeostasis http://purl.obolibrary.org/obo/GO_0055066 GO:0070685 biolink:CellularComponent macropinocytic cup A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin. go-plus.json crown http://purl.obolibrary.org/obo/GO_0070685 CHEBI:32370 biolink:ChemicalSubstance myristoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32370 chebi_ph7_3 GO:0055067 biolink:BiologicalProcess monovalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055067 GO:0070682 biolink:BiologicalProcess proteasome regulatory particle assembly The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex. go-plus.json proteasome regulatory complex assembly http://purl.obolibrary.org/obo/GO_0070682 GO:0055068 biolink:BiologicalProcess cobalt ion homeostasis Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell. go-plus.json cobalt homeostasis http://purl.obolibrary.org/obo/GO_0055068 CHEBI:32372 biolink:ChemicalSubstance palmitoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32372 chebi_ph7_3 GO:0070683 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070683 CHEBI:46992 biolink:ChemicalSubstance 4-amino-4-deoxy-alpha-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46992 CHEBI:46993 biolink:ChemicalSubstance 4-amino-4-deoxy-beta-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46993 CHEBI:46994 biolink:ChemicalSubstance D-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46994 chebi_ph7_3 CHEBI:46995 biolink:ChemicalSubstance alpha-D-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46995 chebi_ph7_3 CHEBI:46996 biolink:ChemicalSubstance beta-D-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46996 chebi_ph7_3 CHEBI:46997 biolink:ChemicalSubstance L-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46997 CHEBI:46998 biolink:ChemicalSubstance ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46998 GO:0080036 biolink:BiologicalProcess regulation of cytokinin-activated signaling pathway Any process that modulates the frequency, rate or extent of cytokinin signaling. go-plus.json regulation of cytokinin mediated signalling|regulation of cytokinin mediated signaling pathway http://purl.obolibrary.org/obo/GO_0080036 GO:0080037 biolink:BiologicalProcess negative regulation of cytokinin-activated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling. go-plus.json negative regulation of cytokinin mediated signalling|negative regulation of cytokinin mediated signaling pathway http://purl.obolibrary.org/obo/GO_0080037 GO:0080038 biolink:BiologicalProcess positive regulation of cytokinin-activated signaling pathway Any process that activates or increases the frequency, rate or extent of cytokinin signaling. go-plus.json positive regulation of cytokinin mediated signalling|positive regulation of cytokinin mediated signaling pathway http://purl.obolibrary.org/obo/GO_0080038 GO:0080039 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080039 GO:0080032 biolink:MolecularActivity methyl jasmonate esterase activity Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol. MetaCyc:RXN-10767 go-plus.json jasmonic acid methyl ester esterase activity|methyl JA esterase activity|MEJA esterase activity http://purl.obolibrary.org/obo/GO_0080032 GO:0080033 biolink:BiologicalProcess response to nitrite Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0080033 GO:0080034 biolink:BiologicalProcess host response to induction by symbiont of tumor, nodule or growth in host Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0080034 CHEBI:46990 biolink:ChemicalSubstance 4-amino-4-deoxy-L-arabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46990 GO:0080035 biolink:BiologicalProcess 2-hydroxy-but-3-enyl glucosinolate biosynthetic process The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables. go-plus.json 2-hydroxy-but-3-enyl glucosinolate biosynthesis|progoitrin biosynthesis|progoitrin biosynthetic process|progoitrin synthesis|2-hydroxy-but-3-enyl glucosinolate anabolism|2-hydroxy-but-3-enyl glucosinolate synthesis|2-hydroxy-but-3-enyl glucosinolate formation http://purl.obolibrary.org/obo/GO_0080035 CHEBI:46991 biolink:ChemicalSubstance 4-amino-4-deoxy-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46991 GO:0055072 biolink:BiologicalProcess iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell. go-plus.json iron homeostasis http://purl.obolibrary.org/obo/GO_0055072 CHEBI:32340 biolink:ChemicalSubstance dTDP-beta-L-daunosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32340 GO:0055073 biolink:BiologicalProcess cadmium ion homeostasis Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell. go-plus.json cadmium homeostasis http://purl.obolibrary.org/obo/GO_0055073 GO:0055074 biolink:BiologicalProcess calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. go-plus.json regulation of calcium ion concentration http://purl.obolibrary.org/obo/GO_0055074 GO:0080030 biolink:MolecularActivity methyl indole-3-acetate esterase activity Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+. MetaCyc:RXN-10711|EC:3.1.1.1 go-plus.json Methyl IAA esterase activity|methyl indole-3-acetate esterase activity|indole-3-Acetic acid methyl ester esterase activity|MeIAA esterase activity http://purl.obolibrary.org/obo/GO_0080030 GO:0055075 biolink:BiologicalProcess potassium ion homeostasis Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055075 GO:0080031 biolink:MolecularActivity methyl salicylate esterase activity Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+. MetaCyc:RXNQT-4366 go-plus.json methylsalicylate esterase activity|MESA esterase activity|salicylic acid methyl ester esterase activity|methyl SA esterase activity http://purl.obolibrary.org/obo/GO_0080031 GO:0055070 biolink:BiologicalProcess copper ion homeostasis Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell. go-plus.json copper homeostasis http://purl.obolibrary.org/obo/GO_0055070 GO:0055071 biolink:BiologicalProcess manganese ion homeostasis Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell. go-plus.json manganese homeostasis http://purl.obolibrary.org/obo/GO_0055071 GO:0055076 biolink:BiologicalProcess transition metal ion homeostasis Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. go-plus.json http://purl.obolibrary.org/obo/GO_0055076 UBERON:0003135 biolink:AnatomicalEntity male reproductive organ A male organ involved in reproduction go-plus.json male reproductive system organ|reproductive organ of male organism|male genital|reproductive structure of male organism|male organism reproductive structure|male organism reproductive system organ|male organism reproductive organ|sex organ of male organism|male sex organ|male reproductive gland/organ|male organism sex organ|reproductive system organ of male organism http://purl.obolibrary.org/obo/UBERON_0003135 GO:0055077 biolink:MolecularActivity gap junction hemi-channel activity A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction. go-plus.json connexon channel activity http://purl.obolibrary.org/obo/GO_0055077 GO:0055078 biolink:BiologicalProcess sodium ion homeostasis Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055078 UBERON:0003133 biolink:AnatomicalEntity reproductive organ An organ involved in reproduction go-plus.json reproductive system organ|genitalia|sex organ|genital organ http://purl.obolibrary.org/obo/UBERON_0003133 UBERON:0003134 biolink:AnatomicalEntity female reproductive organ A female organ involved in reproduction go-plus.json female reproductive system organ|reproductive organ of female organism|reproductive structure of female organism|female organism reproductive system organ|female organism reproductive structure|female organism reproductive organ|sex organ of female organism|female reproductive gland/organ|female sex organ|female organism sex organ|reproductive system organ of female organism http://purl.obolibrary.org/obo/UBERON_0003134 GO:0055079 biolink:BiologicalProcess aluminum ion homeostasis Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell. go-plus.json aluminium ion homeostasis http://purl.obolibrary.org/obo/GO_0055079 CHEBI:46981 biolink:ChemicalSubstance N-acetylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46981 GO:0080029 biolink:BiologicalProcess cellular response to boron-containing substance levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances. go-plus.json cellular response to boron levels http://purl.obolibrary.org/obo/GO_0080029 CHEBI:46987 biolink:ChemicalSubstance alpha-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46987 chebi_ph7_3 UBERON:0003119 biolink:AnatomicalEntity pharyngeal arch artery 2 The vessels formed within the second pair of branchial arches in embryogenesis go-plus.json AA2|2nd aortic arch artery|2nd pharyngeal arch artery|2nd branchial arch artery|hyoid aortic arch|second aortic arch|aortic arch 2|2nd arch artery|second branchial arch artery http://purl.obolibrary.org/obo/UBERON_0003119 CHEBI:46988 biolink:ChemicalSubstance 4-amino-4-deoxyarabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46988 GO:0080025 biolink:MolecularActivity phosphatidylinositol-3,5-bisphosphate binding Binding to phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions. go-plus.json PtdIns(3,5)P2 binding http://purl.obolibrary.org/obo/GO_0080025 GO:0080026 biolink:BiologicalProcess response to indolebutyric acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus. go-plus.json response to indolebutyric acid stimulus|response to indole-3-butyric acid stimulus|response to IBA stimulus http://purl.obolibrary.org/obo/GO_0080026 GO:0080027 biolink:BiologicalProcess response to herbivore Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore. go-plus.json http://purl.obolibrary.org/obo/GO_0080027 GO:0080028 biolink:BiologicalProcess nitrile biosynthetic process The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom. go-plus.json http://purl.obolibrary.org/obo/GO_0080028 GO:0080021 biolink:BiologicalProcess response to benzoic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus. go-plus.json response to benzoic acid stimulus http://purl.obolibrary.org/obo/GO_0080021 GO:0080022 biolink:BiologicalProcess primary root development The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle. go-plus.json http://purl.obolibrary.org/obo/GO_0080022 GO:0080023 biolink:MolecularActivity 3R-hydroxyacyl-CoA dehydratase activity Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O. Reactome:R-HSA-5676637 go-plus.json http://purl.obolibrary.org/obo/GO_0080023 GO:0080024 biolink:BiologicalProcess indolebutyric acid metabolic process The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants. go-plus.json IBA metabolic process|IBA metabolism|indole-3-butyric acid metabolic process http://purl.obolibrary.org/obo/GO_0080024 UBERON:0003120 biolink:AnatomicalEntity pharyngeal arch artery 3 The vessels formed within the third pair of branchial arches in embryogenesis go-plus.json aortic arch 3|3rd arch artery|3rd aortic arch artery|third aortic arch|AA3|3rd pharyngeal arch artery|third branchial arch artery|3rd branchial arch artery|carotid arch http://purl.obolibrary.org/obo/UBERON_0003120 GO:0055083 biolink:BiologicalProcess monovalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055083 UBERON:0003121 biolink:AnatomicalEntity pharyngeal arch artery 4 The vessels formed within the fourth pair of branchial arches in embryogenesis go-plus.json aortic arch 4|fourth branchial arch artery|4th arch artery|AA4|4th aortic arch artery|4th pharyngeal arch artery|systemic arch|4th branchial arch artery|fourth aortic arch http://purl.obolibrary.org/obo/UBERON_0003121 GO:0055084 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055084 GO:0055085 biolink:BiologicalProcess transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json membrane transport|ATP hydrolysis coupled transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast GO:0080020 biolink:BiologicalProcess regulation of coenzyme A biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A. go-plus.json http://purl.obolibrary.org/obo/GO_0080020 GO:0055086 biolink:BiologicalProcess nucleobase-containing small molecule metabolic process The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. go-plus.json nucleobase, nucleoside and nucleotide metabolic process|nucleobase, nucleoside and nucleotide metabolism http://purl.obolibrary.org/obo/GO_0055086 goslim_pombe|goslim_yeast|goslim_drosophila GO:0055080 biolink:BiologicalProcess cation homeostasis Any process involved in the maintenance of an internal steady state of cations within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055080 CHEBI:32356 biolink:ChemicalSubstance 2,3-dihydroxy-trans-cinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32356 CHEBI:32357 biolink:ChemicalSubstance trans-3-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32357 GO:0055081 biolink:BiologicalProcess anion homeostasis Any process involved in the maintenance of an internal steady state of anions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055081 GO:0055082 biolink:BiologicalProcess cellular chemical homeostasis Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055082 CHEBI:46989 biolink:ChemicalSubstance pentosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46989 UBERON:0003128 biolink:AnatomicalEntity cranium Upper portion of the skull that excludes the mandible (when present in the organism). go-plus.json calvarium|upper part of skull|skeletal system of head|set of bones of cranium|skull minus mandible|bones of cranium|epicranial plate|ossa cranii http://purl.obolibrary.org/obo/UBERON_0003128 UBERON:0003129 biolink:AnatomicalEntity skull Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]. go-plus.json skeletal system of head|cranial skeleton http://purl.obolibrary.org/obo/UBERON_0003129 UBERON:0003126 biolink:AnatomicalEntity trachea The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]. go-plus.json cartilaginous trachea|tracheal tubule|windpipe|vertebrate trachea http://purl.obolibrary.org/obo/UBERON_0003126 GO:0055087 biolink:CellularComponent Ski complex A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p. Wikipedia:Ski_complex go-plus.json http://purl.obolibrary.org/obo/GO_0055087 UBERON:0003124 biolink:AnatomicalEntity chorion membrane the outermost extraembryonic membrane go-plus.json fetal chorion|chorion|embryonic chorion|uterine chorion|chorion frondosum|chorion (vertebrates)|chorionic sac http://purl.obolibrary.org/obo/UBERON_0003124 GO:0055088 biolink:BiologicalProcess lipid homeostasis Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055088 UBERON:0003125 biolink:AnatomicalEntity vitelline membrane A structure directly adjacent to the outer surface of the plasma membrane of an ovum. It is composed mostly of protein fibers, with protein receptors needed for sperm binding, binding to sperm plasma membrane receptors. The species-specificity between these receptors contributes to prevention of breeding between different species [Wikipedia]. A protective layer around the egg[FBbt]. go-plus.json zona pellucida - vitelline membrane|m. vitellina|zona pellucida|yolk sac membrane http://purl.obolibrary.org/obo/UBERON_0003125 UBERON:0003122 biolink:AnatomicalEntity pharyngeal arch artery 5 The vessels formed within the fifth pair of pharyngeal arches in embryogenesis. go-plus.json aortic arch 5|AA5|fifth aortic arch http://purl.obolibrary.org/obo/UBERON_0003122 GO:0055089 biolink:BiologicalProcess fatty acid homeostasis Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055089 UBERON:0003123 biolink:AnatomicalEntity pharyngeal arch artery 6 The vessels formed within the sixth pair of branchial arches in embryogenesis go-plus.json aortic arch 6|sixth aortic arch|6th arch artery|sixth branchial arch artery|AA6|6th aortic arch artery|pulmonary arch|6th pharyngeal arch artery|6th branchial arch artery http://purl.obolibrary.org/obo/UBERON_0003123 UBERON:0017750 biolink:AnatomicalEntity proximal mesopodial endochondral element A mesopodial endochondral element that is in the most proximal part of the mesopodial skeleton, connected to the zeugopodial skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0017750 CHEBI:46970 biolink:ChemicalSubstance phytosphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46970 UBERON:0017751 biolink:AnatomicalEntity proximal mesopodial cartilage element A proximal mesopodial endochondral element that is composed primarily of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0017751 CHEBI:46971 biolink:ChemicalSubstance premnaspirodiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_46971 chebi_ph7_3 OBA:0001001 biolink:OntologyClass macromolecular stability go-plus.json http://purl.obolibrary.org/obo/OBA_0001001 CHEBI:46976 biolink:ChemicalSubstance 1,4-thiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46976 UBERON:0003108 biolink:AnatomicalEntity suspensorium (1) the arrangement of bones which supports the jaw from the braincase; (2) in teleost fish, a large, usually triangular, bone which supports the jaw. The teleost suspensorium is formed by fusion of various elements which vary among different taxa. go-plus.json suspensoria|mandibular suspensorium|hyopalatine http://purl.obolibrary.org/obo/UBERON_0003108 GO:0080058 biolink:BiologicalProcess protein deglutathionylation The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage. go-plus.json protein amino acid deglutathionylation http://purl.obolibrary.org/obo/GO_0080058 FAO:0000050 biolink:OntologyClass conidiophore stalk The elongated part of the conidiophore that extends, often aerially, from the growth substrate and supports the structures that bear conidia. go-plus.json http://purl.obolibrary.org/obo/FAO_0000050 GO:0080059 biolink:MolecularActivity flavonol 3-O-arabinosyltransferase activity Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside. go-plus.json http://purl.obolibrary.org/obo/GO_0080059 FAO:0000052 biolink:OntologyClass sporangium A structure within which spores develop. go-plus.json http://purl.obolibrary.org/obo/FAO_0000052 CHEBI:32328 biolink:ChemicalSubstance 3-(cis-5,6-dihydroxycyclohexa-1,3-dienyl)acrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32328 GO:0080054 biolink:MolecularActivity low-affinity nitrate transmembrane transporter activity Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity nitrate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0080054 GO:0080055 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080055 GO:0080056 biolink:BiologicalProcess petal vascular tissue pattern formation Vascular tissue pattern formation as it occurs in the petal of vascular plants. go-plus.json http://purl.obolibrary.org/obo/GO_0080056 GO:0080057 biolink:BiologicalProcess sepal vascular tissue pattern formation Vascular tissue pattern formation as it occurs in the sepal of vascular plants. go-plus.json http://purl.obolibrary.org/obo/GO_0080057 GO:0080050 biolink:BiologicalProcess regulation of seed development Any process that modulates the frequency, rate or extent of seed development. go-plus.json http://purl.obolibrary.org/obo/GO_0080050 GO:0055094 biolink:BiologicalProcess response to lipoprotein particle Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. go-plus.json response to lipoprotein particle stimulus http://purl.obolibrary.org/obo/GO_0055094 GO:0055095 biolink:BiologicalProcess lipoprotein particle mediated signaling A series of molecular signals mediated by the detection of a lipoprotein particle. go-plus.json lipoprotein particle mediated signal transduction|lipoprotein particle-mediated signaling|lipoprotein mediated signalling http://purl.obolibrary.org/obo/GO_0055095 GO:0080051 biolink:BiologicalProcess cutin transport The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface. go-plus.json http://purl.obolibrary.org/obo/GO_0080051 UBERON:0003110 biolink:AnatomicalEntity otic region go-plus.json cranial vault http://purl.obolibrary.org/obo/UBERON_0003110 GO:0055096 biolink:BiologicalProcess low-density lipoprotein particle mediated signaling A series of molecular signals mediated by the detection of low-density lipoprotein particle. go-plus.json low-density lipoprotein particle mediated signal transduction|low-density lipoprotein particle-mediated signaling|low-density lipoprotein mediated signalling http://purl.obolibrary.org/obo/GO_0055096 GO:0080052 biolink:BiologicalProcess response to histidine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0080052 GO:0080053 biolink:BiologicalProcess response to phenylalanine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0080053 GO:0055097 biolink:BiologicalProcess high density lipoprotein particle mediated signaling A series of molecular signals mediated by the detection of high density lipoprotein particle. go-plus.json high density lipoprotein particle mediated signal transduction|high density lipoprotein particle-mediated signaling|high density lipoprotein mediated signalling http://purl.obolibrary.org/obo/GO_0055097 GO:0055090 biolink:BiologicalProcess acylglycerol homeostasis Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell. go-plus.json glyceride homeostasis http://purl.obolibrary.org/obo/GO_0055090 GO:0055091 biolink:BiologicalProcess phospholipid homeostasis Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055091 GO:0055092 biolink:BiologicalProcess sterol homeostasis Any process involved in the maintenance of an internal steady state of sterol within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0055092 GO:0055093 biolink:BiologicalProcess response to hyperoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension. go-plus.json response to hyperoxic stress|response to increased oxygen tension http://purl.obolibrary.org/obo/GO_0055093 CHEBI:32325 biolink:ChemicalSubstance beta-ionone go-plus.json http://purl.obolibrary.org/obo/CHEBI_32325 chebi_ph7_3 UBERON:0003117 biolink:AnatomicalEntity pharyngeal arch 6 The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles go-plus.json 6th pharyngeal arch|branchial arch 4|visceral arch 6|sixth branchial arch|6th arch|sixth visceral arch|gill arch 4|fourth branchial arch|6th visceral arch|sixth pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0003117 CHEBI:46978 biolink:ChemicalSubstance thiazinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46978 UBERON:0003118 biolink:AnatomicalEntity pharyngeal arch artery 1 The vessels formed within the first pair of branchial arches in embryogenesis go-plus.json first branchial arch artery|1st branchial arch artery|AA1|1st aortic arch artery|1st arch artery|1st pharyngeal arch artery|first arch artery|aortic arch 1|first aortic arch|mandibular aortic arch http://purl.obolibrary.org/obo/UBERON_0003118 CHEBI:46979 biolink:ChemicalSubstance N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46979 chebi_ph7_3 UBERON:0003115 biolink:AnatomicalEntity pharyngeal arch 4 contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus go-plus.json branchial arch 2|fourth visceral arch|visceral arch 4|second branchial arch|4th arch|fourth pharyngeal arch|second gill arch|gill arch 2|4th visceral arch|4th branchial arch|4th pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0003115 UBERON:0003116 biolink:AnatomicalEntity pharyngeal arch 5 go-plus.json 5th pharyngeal arch|branchial arch 3|fifth visceral arch|visceral arch 5|gill arch 3|fifth pharyngeal arch|5th visceral arch|third branchial arch http://purl.obolibrary.org/obo/UBERON_0003116 GO:0055098 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055098 UBERON:0003113 biolink:AnatomicalEntity dermatocranium Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]. go-plus.json dendrocranium|dermal skull bones|exocranium|roof of skull|dermal part of skull|roofing bones of the skull|skull exoskeleton|dermal bone cranium|skull roof|dermal skull roof|dermatocranial cover http://purl.obolibrary.org/obo/UBERON_0003113 UBERON:0003114 biolink:AnatomicalEntity pharyngeal arch 3 The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus. go-plus.json 3rd pharyngeal arch|branchial arch 1|first branchial arch|visceral arch 3|3rd arch|gill arch 1|first gill arch|third visceral arch|3rd visceral arch|third pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0003114 GO:0055099 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055099 UBERON:0003111 biolink:AnatomicalEntity sphenoid region Anatomical cluster that forms the floor and sidewalls of the middle part of the cranium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003111 UBERON:0003112 biolink:AnatomicalEntity olfactory region Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ. go-plus.json ethmoid region http://purl.obolibrary.org/obo/UBERON_0003112 CHEBI:46960 biolink:ChemicalSubstance dTMP(-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46960 CHEBI:46961 biolink:ChemicalSubstance phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46961 CHEBI:46963 biolink:ChemicalSubstance 2-aminooctadecene-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46963 CHEBI:46964 biolink:ChemicalSubstance 2-aminooctadec-4-ene-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46964 CHEBI:46965 biolink:ChemicalSubstance (2R,3S)-2-aminooctadec-4-ene-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46965 CHEBI:46966 biolink:ChemicalSubstance 2-amino-1-hydroxyoctadecan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_46966 GO:0080047 biolink:MolecularActivity GDP-L-galactose phosphorylase activity Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP. EC:2.7.7.69|RHEA:27698|MetaCyc:RXNQT-4141 go-plus.json http://purl.obolibrary.org/obo/GO_0080047 GO:0080048 biolink:MolecularActivity GDP-D-glucose phosphorylase activity Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP. EC:2.7.7.78|MetaCyc:RXN-12486|RHEA:30387 go-plus.json http://purl.obolibrary.org/obo/GO_0080048 GO:0080049 biolink:MolecularActivity L-gulono-1,4-lactone dehydrogenase activity Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c. MetaCyc:RXN-1439 go-plus.json http://purl.obolibrary.org/obo/GO_0080049 GO:0080043 biolink:MolecularActivity quercetin 3-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080043 GO:0080044 biolink:MolecularActivity quercetin 7-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080044 GO:0080045 biolink:MolecularActivity quercetin 3'-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080045 GO:0080046 biolink:MolecularActivity quercetin 4'-O-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule. MetaCyc:RXN-10788 go-plus.json http://purl.obolibrary.org/obo/GO_0080046 GO:0080040 biolink:BiologicalProcess positive regulation of cellular response to phosphate starvation Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0080040 GO:0080041 biolink:MolecularActivity ADP-ribose pyrophosphohydrolase activity Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0080041 GO:0080042 biolink:MolecularActivity ADP-glucose pyrophosphohydrolase activity Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0080042 CHEBI:32333 biolink:ChemicalSubstance dTDP-5,5-di-C-methyl-beta-L-lyxose go-plus.json http://purl.obolibrary.org/obo/CHEBI_32333 CHEBI:32336 biolink:ChemicalSubstance dTDP-beta-L-vancosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32336 CHEBI:46967 biolink:ChemicalSubstance L-erythro-sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46967 CHEBI:46968 biolink:ChemicalSubstance 2-aminooctadecane-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46968 UBERON:0003104 biolink:AnatomicalEntity mesenchyme Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme. go-plus.json mesenchyma|mesenchymal tissue|mesenchyme tissue|portion of mesenchymal tissue|portion of mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 CHEBI:46969 biolink:ChemicalSubstance benzoxazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46969 UBERON:0003102 biolink:AnatomicalEntity surface structure Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. go-plus.json surface region|surface feature|surface structures|anatomical surface feature http://purl.obolibrary.org/obo/UBERON_0003102 UBERON:0003103 biolink:AnatomicalEntity compound organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. go-plus.json organ http://purl.obolibrary.org/obo/UBERON_0003103 UBERON:0003100 biolink:AnatomicalEntity female organism Gonochoristic organism that can produce female gametes. go-plus.json female human body|female http://purl.obolibrary.org/obo/UBERON_0003100 UBERON:0003101 biolink:AnatomicalEntity male organism Gonochoristic organism that can produce male gametes. go-plus.json male human body|male http://purl.obolibrary.org/obo/UBERON_0003101 GO:0031229 biolink:CellularComponent intrinsic component of nuclear inner membrane The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to nuclear inner membrane http://purl.obolibrary.org/obo/GO_0031229 GO:0031227 biolink:CellularComponent intrinsic component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0031227 GO:0031228 biolink:CellularComponent intrinsic component of Golgi membrane The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to Golgi membrane http://purl.obolibrary.org/obo/GO_0031228 GO:0006269 biolink:BiologicalProcess DNA replication, synthesis of RNA primer The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis. go-plus.json replication priming http://purl.obolibrary.org/obo/GO_0006269 GO:0031225 biolink:CellularComponent anchored component of membrane The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json anchored to membrane http://purl.obolibrary.org/obo/GO_0031225 GO:0031226 biolink:CellularComponent intrinsic component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to plasma membrane http://purl.obolibrary.org/obo/GO_0031226 GO:0045875 biolink:BiologicalProcess negative regulation of sister chromatid cohesion Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion. go-plus.json down regulation of sister chromatid cohesion|downregulation of sister chromatid cohesion|down-regulation of sister chromatid cohesion|inhibition of sister chromatid cohesion http://purl.obolibrary.org/obo/GO_0045875 GO:0006267 biolink:BiologicalProcess pre-replicative complex assembly involved in nuclear cell cycle DNA replication The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation. go-plus.json pre-replicative complex formation|pre-replicative complex assembly|nuclear pre-replicative complex assembly|pre-RC complex assembly http://purl.obolibrary.org/obo/GO_0006267 GO:0045876 biolink:BiologicalProcess positive regulation of sister chromatid cohesion Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion. go-plus.json upregulation of sister chromatid cohesion|up regulation of sister chromatid cohesion|activation of sister chromatid cohesion|stimulation of sister chromatid cohesion|up-regulation of sister chromatid cohesion http://purl.obolibrary.org/obo/GO_0045876 GO:0006268 biolink:BiologicalProcess DNA unwinding involved in DNA replication The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. go-plus.json DNA unwinding during replication|DNA unwinding factor http://purl.obolibrary.org/obo/GO_0006268 GO:0006265 biolink:BiologicalProcess DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number. go-plus.json DNA underwinding http://purl.obolibrary.org/obo/GO_0006265 GO:0045873 biolink:BiologicalProcess negative regulation of sevenless signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway. go-plus.json down-regulation of sevenless signaling pathway|negative regulation of sev signaling pathway|inhibition of sevenless signaling pathway|negative regulation of sevenless signalling pathway|down regulation of sevenless signaling pathway|downregulation of sevenless signaling pathway http://purl.obolibrary.org/obo/GO_0045873 GO:0045874 biolink:BiologicalProcess positive regulation of sevenless signaling pathway Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway. go-plus.json up regulation of sevenless signaling pathway|activation of sevenless signaling pathway|stimulation of sevenless signaling pathway|positive regulation of sev signaling pathway|up-regulation of sevenless signaling pathway|upregulation of sevenless signaling pathway|positive regulation of sevenless signalling pathway http://purl.obolibrary.org/obo/GO_0045874 GO:0006266 biolink:BiologicalProcess DNA ligation The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0006266 goslim_pir GO:0045871 biolink:BiologicalProcess obsolete negative regulation of rhodopsin gene expression OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression. go-plus.json negative regulation of rhodopsin gene activity|downregulation of rhodopsin gene activity|down-regulation of rhodopsin gene activity|inhibition of rhodopsin gene activity|down regulation of rhodopsin gene activity http://purl.obolibrary.org/obo/GO_0045871 GO:0006263 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006263 GO:0006264 biolink:BiologicalProcess mitochondrial DNA replication The process in which new strands of DNA are synthesized in the mitochondrion. go-plus.json mtDNA synthesis|mtDNA replication|mitochondrial DNA synthesis|replication of mitochondrial DNA http://purl.obolibrary.org/obo/GO_0006264 GO:0045872 biolink:BiologicalProcess obsolete positive regulation of rhodopsin gene expression OBSOLETE. Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression. go-plus.json up regulation of rhodopsin gene activity|activation of rhodopsin gene activity|stimulation of rhodopsin gene activity|up-regulation of rhodopsin gene activity|upregulation of rhodopsin gene activity|positive regulation of rhodopsin gene activity http://purl.obolibrary.org/obo/GO_0045872 GO:0006261 biolink:BiologicalProcess DNA-dependent DNA replication A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. go-plus.json http://purl.obolibrary.org/obo/GO_0006261 CHEBI:81276 biolink:ChemicalSubstance allodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81276 GO:0045870 biolink:BiologicalProcess positive regulation of single stranded viral RNA replication via double stranded DNA intermediate Any process that activates or increases the frequency, rate or extent of retroviral genome replication. go-plus.json up-regulation of retroviral genome replication|upregulation of retroviral genome replication|up regulation of retroviral genome replication|activation of retroviral genome replication|positive regulation of retroviral genome replication|stimulation of retroviral genome replication http://purl.obolibrary.org/obo/GO_0045870 GO:0006262 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006262 GO:0070839 biolink:BiologicalProcess metal ion export The directed movement of metal cations, out of a cell or organelle. go-plus.json divalent metal ion export http://purl.obolibrary.org/obo/GO_0070839 GO:0006270 biolink:BiologicalProcess DNA replication initiation The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate. go-plus.json DNA re-replication initiation|DNA endoreduplication initiation|DNA-dependent DNA replication initiation http://purl.obolibrary.org/obo/GO_0006270 GO:0006271 biolink:BiologicalProcess DNA strand elongation involved in DNA replication The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. go-plus.json DNA replication elongation|DNA strand elongation during DNA replication http://purl.obolibrary.org/obo/GO_0006271 GO:0070837 biolink:BiologicalProcess dehydroascorbic acid transport The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C. go-plus.json dehydroascorbate transport http://purl.obolibrary.org/obo/GO_0070837 GO:0070838 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070838 GO:0045879 biolink:BiologicalProcess negative regulation of smoothened signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling. go-plus.json negative regulation of smoothened activity|negative regulation of smoothened signalling pathway|negative regulation of hedgehog signaling pathway|negative regulation of smoothened receptor activity by patched|negative regulation of smoothened by patched|downregulation of smoothened signaling pathway|down regulation of smoothened signaling pathway|inhibition of smoothened signaling pathway|negative regulation of hh signaling pathway|down-regulation of smoothened signaling pathway http://purl.obolibrary.org/obo/GO_0045879 GO:0070835 biolink:MolecularActivity chromium ion transmembrane transporter activity Enables the transfer of chromium (Cr) ions from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0070835 GO:0070836 biolink:BiologicalProcess caveola assembly The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. go-plus.json caveolar biogenesis|caveola formation http://purl.obolibrary.org/obo/GO_0070836 GO:0070833 biolink:BiologicalProcess phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine. MetaCyc:PWY4FS-3 go-plus.json http://purl.obolibrary.org/obo/GO_0070833 GO:0045877 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045877 GO:0045878 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045878 GO:0070834 biolink:BiologicalProcess phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine. MetaCyc:PWY4FS-4 go-plus.json http://purl.obolibrary.org/obo/GO_0070834 GO:0070831 biolink:BiologicalProcess basement membrane assembly The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0070831 GO:0031223 biolink:BiologicalProcess auditory behavior The behavior of an organism in response to a sound. go-plus.json behavioural response to sound|behavioral response to sound|auditory behaviour http://purl.obolibrary.org/obo/GO_0031223 GO:0070832 biolink:BiologicalProcess phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine. MetaCyc:PWY4FS-2 go-plus.json http://purl.obolibrary.org/obo/GO_0070832 GO:0031224 biolink:CellularComponent intrinsic component of membrane The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. go-plus.json intrinsic to membrane http://purl.obolibrary.org/obo/GO_0031224 goslim_metagenomics GO:0031221 biolink:BiologicalProcess arabinan metabolic process The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues. go-plus.json arabinan metabolism http://purl.obolibrary.org/obo/GO_0031221 GO:0070830 biolink:BiologicalProcess bicellular tight junction assembly The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. go-plus.json tight junction formation http://purl.obolibrary.org/obo/GO_0070830 GO:0031222 biolink:BiologicalProcess arabinan catabolic process The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues. go-plus.json arabinan catabolism|arabinan degradation|arabinan breakdown http://purl.obolibrary.org/obo/GO_0031222 GO:0031220 biolink:MolecularActivity maltodextrin phosphorylase activity Catalysis of the reaction: maltodextrin = glucose-1-phosphate. MetaCyc:RXN-9025|MetaCyc:RXN0-5182|RHEA:29691 go-plus.json http://purl.obolibrary.org/obo/GO_0031220 GO:0021890 biolink:BiologicalProcess olfactory bulb interneuron fate commitment The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb. go-plus.json http://purl.obolibrary.org/obo/GO_0021890 GO:0031218 biolink:MolecularActivity arabinogalactan endo-1,4-beta-galactosidase activity Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans. MetaCyc:3.2.1.89-RXN|EC:3.2.1.89 go-plus.json galactanase activity|arabinogalactan 4-beta-D-galactanohydrolase activity|arabinogalactanase activity|endo-1,4-beta-galactanase activity http://purl.obolibrary.org/obo/GO_0031218 GO:0021891 biolink:BiologicalProcess olfactory bulb interneuron development The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0021891 GO:0021892 biolink:BiologicalProcess cerebral cortex GABAergic interneuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021892 GO:0031219 biolink:MolecularActivity levanase activity Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units. MetaCyc:3.2.1.65-RXN|EC:3.2.1.65 go-plus.json levan hydrolase activity|2,6-beta-D-fructan fructanohydrolase activity http://purl.obolibrary.org/obo/GO_0031219 GO:0031216 biolink:MolecularActivity neopullulanase activity Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose). MetaCyc:3.2.1.135-RXN|EC:3.2.1.135 go-plus.json pullulanase II activity|pullulan 4-D-glucanohydrolase (panose-forming) http://purl.obolibrary.org/obo/GO_0031216 GO:0021893 biolink:BiologicalProcess cerebral cortex GABAergic interneuron fate commitment The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021893 GO:0021894 biolink:BiologicalProcess cerebral cortex GABAergic interneuron development The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0021894 GO:0031217 biolink:MolecularActivity glucan 1,4-beta-glucosidase activity Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units. MetaCyc:3.2.1.74-RXN|EC:3.2.1.74 go-plus.json exo-1,4-beta-glucosidase activity|beta-1,4-glucanase activity|beta-1,4-beta-glucanase activity|1,4-beta-D-glucan glucohydrolase activity|exo-beta-1,4-glucanase activity|exo-1,4-beta-glucanase activity|exocellulase activity|exo-1,4-beta-D-glucosidase activity|exo-beta-1,4-glucosidase activity http://purl.obolibrary.org/obo/GO_0031217 GO:0021895 biolink:BiologicalProcess cerebral cortex neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021895 GO:0031214 biolink:BiologicalProcess biomineral tissue development Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. Wikipedia:Biomineralization go-plus.json http://purl.obolibrary.org/obo/GO_0031214 GO:0021896 biolink:BiologicalProcess forebrain astrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. go-plus.json http://purl.obolibrary.org/obo/GO_0021896 GO:0031215 biolink:BiologicalProcess shell calcification The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell. go-plus.json http://purl.obolibrary.org/obo/GO_0031215 GO:0045886 biolink:BiologicalProcess negative regulation of synaptic assembly at neuromuscular junction Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction. go-plus.json downregulation of synaptic growth at neuromuscular junction|down-regulation of synaptic growth at neuromuscular junction|negative regulation of synaptic growth at neuromuscular junction|inhibition of synaptic growth at neuromuscular junction|down regulation of synaptic growth at neuromuscular junction http://purl.obolibrary.org/obo/GO_0045886 GO:0006278 biolink:BiologicalProcess RNA-dependent DNA biosynthetic process A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand. go-plus.json http://purl.obolibrary.org/obo/GO_0006278 GO:0006279 biolink:BiologicalProcess premeiotic DNA replication The replication of DNA that precedes meiotic cell division. go-plus.json DNA replication involved in S phase involved in meiotic cell cycle|meiotic cell cycle DNA replication|DNA replication during S phase involved in meiotic cell cycle|nuclear cell cycle DNA replication involved in meiotic cell cycle|meiotic nuclear cell cycle DNA replication|meiotic DNA synthesis|premeiotic DNA synthesis|meiotic DNA replication|DNA replication involved in S-phase involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0006279 GO:0045887 biolink:BiologicalProcess positive regulation of synaptic assembly at neuromuscular junction Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction. go-plus.json up regulation of synaptic growth at neuromuscular junction|activation of synaptic growth at neuromuscular junction|stimulation of synaptic growth at neuromuscular junction|positive regulation of synaptic growth at neuromuscular junction|up-regulation of synaptic growth at neuromuscular junction|upregulation of synaptic growth at neuromuscular junction http://purl.obolibrary.org/obo/GO_0045887 GO:0045884 biolink:BiologicalProcess obsolete regulation of survival gene product expression OBSOLETE. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. go-plus.json regulation of survival gene product activity|regulation of survival gene products|regulation of survival gene product expression http://purl.obolibrary.org/obo/GO_0045884 GO:0006276 biolink:BiologicalProcess plasmid maintenance The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0006276 goslim_pir GO:0045885 biolink:BiologicalProcess obsolete positive regulation of survival gene product expression OBSOLETE. Any process that activates or increases the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. go-plus.json positive regulation of survival gene product activity|up-regulation of survival gene product activity|activation of survival gene product activity|positive regulation of survival gene products|up regulation of survival gene product activity|stimulation of survival gene product activity|upregulation of survival gene product activity|positive regulation of survival gene product expression http://purl.obolibrary.org/obo/GO_0045885 GO:0006277 biolink:BiologicalProcess DNA amplification The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0006277 GO:0045882 biolink:BiologicalProcess negative regulation of sulfur utilization Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization. go-plus.json down-regulation of sulfur utilization|downregulation of sulfur utilization|down regulation of sulfur utilization|inhibition of sulfur utilization|negative regulation of sulphur utilization http://purl.obolibrary.org/obo/GO_0045882 GO:0006274 biolink:BiologicalProcess DNA replication termination The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet. go-plus.json http://purl.obolibrary.org/obo/GO_0006274 GO:0045883 biolink:BiologicalProcess positive regulation of sulfur utilization Any process that activates or increases the frequency, rate or extent of sulfur utilization. go-plus.json stimulation of sulfur utilization|up-regulation of sulfur utilization|activation of sulfur utilization|up regulation of sulfur utilization|upregulation of sulfur utilization|positive regulation of sulphur utilization http://purl.obolibrary.org/obo/GO_0045883 GO:0006275 biolink:BiologicalProcess regulation of DNA replication Any process that modulates the frequency, rate or extent of DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0006275 GO:0045880 biolink:BiologicalProcess positive regulation of smoothened signaling pathway Any process that activates or increases the frequency, rate or extent of smoothened signaling. go-plus.json stimulation of smoothened signaling pathway|up-regulation of smoothened signaling pathway|activation of smoothened signaling pathway|positive regulation of smoothened signalling pathway|positive regulation of smoothened receptor activity by patched|positive regulation of hh signaling pathway|up regulation of smoothened signaling pathway|positive regulation of hedgehog signaling pathway|positive regulation of smoothened by patched|upregulation of smoothened signaling pathway http://purl.obolibrary.org/obo/GO_0045880 GO:0070819 biolink:MolecularActivity menaquinone-dependent protoporphyrinogen oxidase activity Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone. go-plus.json protoporphyrinogen-IX:menaquinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0070819 GO:0006272 biolink:BiologicalProcess leading strand elongation The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork. go-plus.json http://purl.obolibrary.org/obo/GO_0006272 GO:0045881 biolink:BiologicalProcess positive regulation of sporulation resulting in formation of a cellular spore Any process that activates or increases the frequency, rate or extent of sporulation. go-plus.json stimulation of sporulation|up-regulation of sporulation|upregulation of sporulation|up regulation of sporulation|activation of sporulation http://purl.obolibrary.org/obo/GO_0045881 GO:0006273 biolink:BiologicalProcess lagging strand elongation The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. go-plus.json http://purl.obolibrary.org/obo/GO_0006273 GO:0006281 biolink:BiologicalProcess DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. Wikipedia:DNA_repair go-plus.json http://purl.obolibrary.org/obo/GO_0006281 goslim_drosophila|goslim_pombe|goslim_yeast|goslim_pir GO:0070828 biolink:BiologicalProcess heterochromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. go-plus.json heterochromatin organisation http://purl.obolibrary.org/obo/GO_0070828 GO:0006282 biolink:BiologicalProcess regulation of DNA repair Any process that modulates the frequency, rate or extent of DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0006282 goslim_metagenomics GO:0070829 biolink:BiologicalProcess obsolete heterochromatin maintenance OBSOLETE. The chromatin organization process that preserves heterochromatin in a stable functional or structural state. go-plus.json maintenance of heterochromatic silencing|heterochromatin maintenance involved in chromatin silencing|maintenance of chromatin silencing http://purl.obolibrary.org/obo/GO_0070829 GO:0070826 biolink:CellularComponent paraferritin complex A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme. go-plus.json http://purl.obolibrary.org/obo/GO_0070826 GO:0070827 biolink:BiologicalProcess obsolete chromatin maintenance OBSOLETE. The chromatin organization process that preserves chromatin in a stable functional or structural state. go-plus.json http://purl.obolibrary.org/obo/GO_0070827 GO:0006280 biolink:BiologicalProcess obsolete mutagenesis OBSOLETE. The process by which genetic material undergoes a detectable and heritable structural change. There are three categories of mutation: genome mutations, involving addition or subtraction of one or more whole chromosomes; chromosome mutations, which alter the structure of chromosomes; and gene mutations, where the structure of a gene is altered at the molecular level. go-plus.json mutagenesis http://purl.obolibrary.org/obo/GO_0006280 GO:0070824 biolink:CellularComponent SHREC complex A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures. go-plus.json Snf2/HDAC containing repressor complex|Snf2/Hdac repressive complex http://purl.obolibrary.org/obo/GO_0070824 GO:0070825 biolink:CellularComponent micropyle An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization. go-plus.json http://purl.obolibrary.org/obo/GO_0070825 GO:0045888 biolink:BiologicalProcess obsolete regulation of transcription of homeotic gene (Polycomb group) OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the Polycomb group. go-plus.json regulation of transcription of homeotic gene (Polycomb group) http://purl.obolibrary.org/obo/GO_0045888 GO:0070822 biolink:CellularComponent Sin3-type complex Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070822 GO:0045889 biolink:BiologicalProcess obsolete positive regulation of transcription of homeotic gene (Polycomb group) OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the Polycomb group. go-plus.json positive regulation of transcription of homeotic gene (Polycomb group) http://purl.obolibrary.org/obo/GO_0045889 GO:0070823 biolink:CellularComponent HDA1 complex A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p. go-plus.json http://purl.obolibrary.org/obo/GO_0070823 GO:0070820 biolink:CellularComponent tertiary granule A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells. go-plus.json gelatinase granule http://purl.obolibrary.org/obo/GO_0070820 GO:0031212 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031212 GO:0021897 biolink:BiologicalProcess forebrain astrocyte development The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. go-plus.json http://purl.obolibrary.org/obo/GO_0021897 GO:0031213 biolink:CellularComponent RSF complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters). go-plus.json remodeling and spacing factor complex http://purl.obolibrary.org/obo/GO_0031213 GO:0021898 biolink:BiologicalProcess commitment of multipotent stem cells to neuronal lineage in forebrain The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021898 GO:0070821 biolink:CellularComponent tertiary granule membrane The lipid bilayer surrounding a tertiary granule. go-plus.json http://purl.obolibrary.org/obo/GO_0070821 GO:0031210 biolink:MolecularActivity phosphatidylcholine binding Binding to a phosphatidylcholine, a glycophospholipid in which a phosphatidyl group is esterified to the hydroxyl group of choline. go-plus.json http://purl.obolibrary.org/obo/GO_0031210 GO:0021899 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. go-plus.json fibroblast growth factor receptor signalling pathway involved in forebrain neuron fate commitment http://purl.obolibrary.org/obo/GO_0021899 GO:0031211 biolink:CellularComponent endoplasmic reticulum palmitoyltransferase complex A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0031211 GO:0031209 biolink:CellularComponent SCAR complex A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction. go-plus.json WRC|WAVE regulatory complex|WAVE complex http://purl.obolibrary.org/obo/GO_0031209 GO:0045890 biolink:BiologicalProcess obsolete regulation of transcription of homeotic gene (trithorax group) OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the trithorax group. go-plus.json regulation of transcription of homeotic gene (trithorax group) http://purl.obolibrary.org/obo/GO_0045890 GO:0021880 biolink:BiologicalProcess Notch signaling pathway involved in forebrain neuron fate commitment The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. go-plus.json Notch signalling pathway involved in forebrain neuron fate commitment http://purl.obolibrary.org/obo/GO_0021880 GO:0031207 biolink:CellularComponent Sec62/Sec63 complex A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p. go-plus.json Sec62/63 complex|ER protein translocation subcomplex http://purl.obolibrary.org/obo/GO_0031207 GO:0021881 biolink:BiologicalProcess Wnt-activated signaling pathway involved in forebrain neuron fate commitment The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain. go-plus.json Wnt receptor signaling pathway involved in forebrain neuron fate commitment|Wnt receptor signalling pathway involved in forebrain neuron fate commitment|Wnt-activated signaling pathway involved in forebrain neuron fate commitment http://purl.obolibrary.org/obo/GO_0021881 GO:0031208 biolink:MolecularActivity POZ domain binding Binding to a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors. go-plus.json broad-complex, tramtrack, and bric-a-brac domain binding|BTB domain http://purl.obolibrary.org/obo/GO_0031208 GO:0006249 biolink:BiologicalProcess dCMP catabolic process The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate. go-plus.json dCMP catabolism|dCMP degradation|dCMP breakdown http://purl.obolibrary.org/obo/GO_0006249 GO:0021882 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021882 GO:0031205 biolink:CellularComponent endoplasmic reticulum Sec complex An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031205 goslim_pir GO:0021883 biolink:BiologicalProcess obsolete cell cycle arrest of committed forebrain neuronal progenitor cell OBSOLETE. The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021883 GO:0031206 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031206 GO:0006247 biolink:BiologicalProcess obsolete TTP reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json TTP reduction http://purl.obolibrary.org/obo/GO_0006247 GO:0021884 biolink:BiologicalProcess forebrain neuron development The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0021884 GO:0031203 biolink:BiologicalProcess posttranslational protein targeting to membrane, docking The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex. go-plus.json protein docking during posttranslational protein targeting to membrane|posttranslational protein membrane targeting, docking|Sec-translated protein complex assembly http://purl.obolibrary.org/obo/GO_0031203 GO:0021885 biolink:BiologicalProcess forebrain cell migration The orderly movement of a cell from one site to another at least one of which is located in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021885 GO:0006248 biolink:BiologicalProcess CMP catabolic process The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate. go-plus.json CMP degradation|CMP catabolism|CMP breakdown http://purl.obolibrary.org/obo/GO_0006248 GO:0031204 biolink:BiologicalProcess posttranslational protein targeting to membrane, translocation The process in which a protein translocates through the ER membrane posttranslationally. go-plus.json protein translocation during posttranslational protein targeting to membrane|posttranslational protein membrane targeting, translocation http://purl.obolibrary.org/obo/GO_0031204 GO:0006245 biolink:BiologicalProcess TDP catabolic process The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate. go-plus.json TDP catabolism|TDP degradation|TDP breakdown http://purl.obolibrary.org/obo/GO_0006245 GO:0045897 biolink:BiologicalProcess obsolete positive regulation of transcription during mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle. go-plus.json mitotic activation of transcription|up regulation of transcription during mitosis|positive regulation of transcription, mitotic|upregulation of transcription during mitosis|stimulation of transcription during mitosis|activation of transcription during mitosis|up-regulation of transcription during mitosis http://purl.obolibrary.org/obo/GO_0045897 GO:0006246 biolink:BiologicalProcess dTDP catabolic process The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate. go-plus.json dTDP degradation|dTDP breakdown|dTDP catabolism http://purl.obolibrary.org/obo/GO_0006246 GO:0045898 biolink:BiologicalProcess regulation of RNA polymerase II transcription preinitiation complex assembly Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. go-plus.json regulation of RNA polymerase II transcriptional preinitiation complex assembly|regulation of RNA polymerase II transcriptional preinitiation complex formation|regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|regulation of RNA polymerase II transcriptional pre-initiation complex assembly http://purl.obolibrary.org/obo/GO_0045898 GO:0045895 biolink:BiologicalProcess positive regulation of mating-type specific transcription, DNA-templated Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription. go-plus.json up-regulation of transcription, mating-type specific|positive regulation of mating-type specific transcription, DNA-dependent|upregulation of transcription, mating-type specific|up regulation of transcription, mating-type specific|activation of transcription, mating-type specific|stimulation of transcription, mating-type specific http://purl.obolibrary.org/obo/GO_0045895 GO:0006243 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006243 GO:0045896 biolink:BiologicalProcess obsolete regulation of transcription during mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription that occurs during the mitotic cell cycle. go-plus.json regulation of transcription, mitotic|mitotic regulation of transcription http://purl.obolibrary.org/obo/GO_0045896 GO:0006244 biolink:BiologicalProcess pyrimidine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine nucleotide degradation|pyrimidine nucleotide breakdown|pyrimidine nucleotide catabolism http://purl.obolibrary.org/obo/GO_0006244 GO:0045893 biolink:BiologicalProcess positive regulation of transcription, DNA-templated Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. go-plus.json upregulation of transcription, DNA-dependent|stimulation of transcription, DNA-dependent|positive regulation of transcription, DNA-dependent|upregulation of gene-specific transcription|activation of transcription, DNA-dependent|up-regulation of transcription, DNA-dependent|transcription activator activity|stimulation of gene-specific transcription|up regulation of gene-specific transcription|positive regulation of cellular transcription, DNA-dependent|positive regulation of gene-specific transcription|up regulation of transcription, DNA-dependent|activation of gene-specific transcription|up-regulation of gene-specific transcription http://purl.obolibrary.org/obo/GO_0045893 GO:0006241 biolink:BiologicalProcess CTP biosynthetic process The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate. go-plus.json CTP biosynthesis|CTP anabolism|CTP synthesis|CTP formation http://purl.obolibrary.org/obo/GO_0006241 GO:0045894 biolink:BiologicalProcess negative regulation of mating-type specific transcription, DNA-templated Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription. go-plus.json inhibition of transcription, mating-type specific|negative regulation of mating-type specific transcription, DNA-dependent|down regulation of transcription, mating-type specific|downregulation of transcription, mating-type specific|down-regulation of transcription, mating-type specific http://purl.obolibrary.org/obo/GO_0045894 GO:0006242 biolink:BiologicalProcess dCTP biosynthetic process The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate. go-plus.json dCTP formation|dCTP anabolism|dCTP biosynthesis|dCTP synthesis http://purl.obolibrary.org/obo/GO_0006242 GO:0045891 biolink:BiologicalProcess obsolete negative regulation of transcription of homeotic gene (trithorax group) OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the trithorax group. go-plus.json negative regulation of transcription of homeotic gene (trithorax group) http://purl.obolibrary.org/obo/GO_0045891 CHEBI:81298 biolink:ChemicalSubstance beta-muricholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81298 GO:0045892 biolink:BiologicalProcess negative regulation of transcription, DNA-templated Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. go-plus.json negative regulation of transcription, DNA-dependent|inhibition of gene-specific transcription|down regulation of gene-specific transcription|transcription repressor activity|downregulation of gene-specific transcription|down-regulation of transcription, DNA-dependent|negative regulation of cellular transcription, DNA-dependent|negative regulation of gene-specific transcription|down-regulation of gene-specific transcription|downregulation of transcription, DNA-dependent|down regulation of transcription, DNA-dependent|inhibition of transcription, DNA-dependent http://purl.obolibrary.org/obo/GO_0045892 GO:0006240 biolink:BiologicalProcess dCDP biosynthetic process The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate. go-plus.json dCDP anabolism|dCDP biosynthesis|dCDP synthesis|dCDP formation http://purl.obolibrary.org/obo/GO_0006240 GO:0070859 biolink:BiologicalProcess positive regulation of bile acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. go-plus.json upregulation of bile acid biosynthetic process|positive regulation of bile acid anabolism|positive regulation of bile acid synthesis|stimulation of bile acid biosynthetic process|positive regulation of bile acid formation|up-regulation of bile acid biosynthetic process|activation of bile acid biosynthetic process|positive regulation of bile acid biosynthesis|up regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0070859 GO:0070857 biolink:BiologicalProcess regulation of bile acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. go-plus.json regulation of bile acid anabolism|regulation of bile acid biosynthesis|regulation of bile acid synthesis|regulation of bile acid formation http://purl.obolibrary.org/obo/GO_0070857 GO:0070858 biolink:BiologicalProcess negative regulation of bile acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. go-plus.json down regulation of bile acid biosynthetic process|inhibition of bile acid biosynthetic process|negative regulation of bile acid anabolism|negative regulation of bile acid synthesis|negative regulation of bile acid formation|negative regulation of bile acid biosynthesis|down-regulation of bile acid biosynthetic process|downregulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0070858 GO:0045899 biolink:BiologicalProcess positive regulation of RNA polymerase II transcription preinitiation complex assembly Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. go-plus.json positive regulation of RNA polymerase II transcriptional pre-initiation complex assembly|up regulation of RNA polymerase II transcriptional preinitiation complex assembly|upregulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional preinitiation complex formation|stimulation of RNA polymerase II transcriptional preinitiation complex assembly|up-regulation of RNA polymerase II transcriptional preinitiation complex assembly|activation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly http://purl.obolibrary.org/obo/GO_0045899 GO:0070855 biolink:MolecularActivity myosin VI head/neck binding Binding to the head/neck region of a myosin VI heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0070855 GO:0070856 biolink:MolecularActivity myosin VI light chain binding Binding to a light chain of a myosin VI complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070856 GO:0021886 biolink:BiologicalProcess hypothalamus gonadotrophin-releasing hormone neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter. go-plus.json hypothalamus gonadotropin-releasing hormone neuron differentiation http://purl.obolibrary.org/obo/GO_0021886 GO:0070853 biolink:MolecularActivity myosin VI binding Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0070853 GO:0031201 biolink:CellularComponent SNARE complex A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. go-plus.json http://purl.obolibrary.org/obo/GO_0031201 GO:0021887 biolink:BiologicalProcess hypothalamus gonadotrophin-releasing hormone neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone. go-plus.json hypothalamus gonadotropin-releasing hormone neuron fate commitment http://purl.obolibrary.org/obo/GO_0021887 GO:0070854 biolink:MolecularActivity myosin VI heavy chain binding Binding to a heavy chain of a myosin VI complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070854 GO:0031202 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031202 GO:0070851 biolink:MolecularActivity growth factor receptor binding Binding to a growth factor receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070851 GO:0021888 biolink:BiologicalProcess hypothalamus gonadotrophin-releasing hormone neuron development The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell. go-plus.json hypothalamus gonadotropin-releasing hormone neuron development http://purl.obolibrary.org/obo/GO_0021888 GO:0070852 biolink:CellularComponent cell body fiber A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches. go-plus.json primary neurite|cell body fibre http://purl.obolibrary.org/obo/GO_0070852 GO:0021889 biolink:BiologicalProcess olfactory bulb interneuron differentiation The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb. go-plus.json http://purl.obolibrary.org/obo/GO_0021889 GO:0031200 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031200 GO:0070850 biolink:CellularComponent TACC/TOG complex A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0070850 GO:0021870 biolink:BiologicalProcess Cajal-Retzius cell differentiation The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. go-plus.json http://purl.obolibrary.org/obo/GO_0021870 GO:0021871 biolink:BiologicalProcess forebrain regionalization The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops. go-plus.json http://purl.obolibrary.org/obo/GO_0021871 GO:0021872 biolink:BiologicalProcess forebrain generation of neurons The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. go-plus.json generation of neurons in forebrain http://purl.obolibrary.org/obo/GO_0021872 GO:0006258 biolink:BiologicalProcess UDP-glucose catabolic process The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. go-plus.json UDP-glucose conversion|UDP-glucose catabolism|UDP-glucose degradation|UDP-glucose breakdown http://purl.obolibrary.org/obo/GO_0006258 GO:0021873 biolink:BiologicalProcess forebrain neuroblast division The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast. go-plus.json http://purl.obolibrary.org/obo/GO_0021873 GO:0006259 biolink:BiologicalProcess DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. go-plus.json DNA metabolism|cellular DNA metabolism http://purl.obolibrary.org/obo/GO_0006259 goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics GO:0021874 biolink:BiologicalProcess Wnt signaling pathway involved in forebrain neuroblast division The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain. go-plus.json Wnt receptor signaling pathway involved in forebrain neuroblast division|Wnt receptor signalling pathway in forebrain neuroblast division|Wnt-activated signaling pathway involved in forebrain neuroblast division http://purl.obolibrary.org/obo/GO_0021874 GO:0006256 biolink:BiologicalProcess UDP catabolic process The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate. go-plus.json UDP catabolism|UDP degradation|UDP breakdown http://purl.obolibrary.org/obo/GO_0006256 GO:0006257 biolink:BiologicalProcess dUDP catabolic process The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate. go-plus.json dUDP breakdown|dUDP catabolism|dUDP degradation http://purl.obolibrary.org/obo/GO_0006257 GO:0006254 biolink:BiologicalProcess CTP catabolic process The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate. go-plus.json CTP catabolism|CTP degradation|CTP hydrolysis|CTP breakdown http://purl.obolibrary.org/obo/GO_0006254 GO:0006255 biolink:BiologicalProcess obsolete UDP reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json UDP reduction http://purl.obolibrary.org/obo/GO_0006255 GO:0006252 biolink:BiologicalProcess obsolete CTP reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json CTP reduction http://purl.obolibrary.org/obo/GO_0006252 GO:0006253 biolink:BiologicalProcess dCTP catabolic process The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate. go-plus.json dCTP breakdown|dCTP catabolism|dCTP degradation http://purl.obolibrary.org/obo/GO_0006253 GO:0006250 biolink:BiologicalProcess obsolete CDP reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json CDP reduction http://purl.obolibrary.org/obo/GO_0006250 GO:0006251 biolink:BiologicalProcess dCDP catabolic process The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate. go-plus.json dCDP degradation|dCDP breakdown|dCDP catabolism http://purl.obolibrary.org/obo/GO_0006251 GO:0006260 biolink:BiologicalProcess DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. Wikipedia:DNA_replication go-plus.json http://purl.obolibrary.org/obo/GO_0006260 goslim_pir|goslim_drosophila|goslim_pombe|goslim_yeast GO:0070848 biolink:BiologicalProcess response to growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. go-plus.json response to growth factor stimulus http://purl.obolibrary.org/obo/GO_0070848 GO:0070849 biolink:BiologicalProcess response to epidermal growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. go-plus.json response to epidermal growth factor stimulus|response to EGF stimulus http://purl.obolibrary.org/obo/GO_0070849 GO:0070846 biolink:BiologicalProcess Hsp90 deacetylation The modification of an Hsp90 protein by removal of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0070846 GO:0070847 biolink:CellularComponent core mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. go-plus.json S mediator complex|C mediator complex http://purl.obolibrary.org/obo/GO_0070847 GO:0070844 biolink:BiologicalProcess polyubiquitinated protein transport The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell. go-plus.json polyubiquitylated protein transport http://purl.obolibrary.org/obo/GO_0070844 GO:0070845 biolink:BiologicalProcess polyubiquitinated misfolded protein transport The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell. go-plus.json polyubiquitylated misfolded protein transport|misfolded polyubiquitinated protein transport http://purl.obolibrary.org/obo/GO_0070845 GO:0070842 biolink:BiologicalProcess aggresome assembly The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein. go-plus.json http://purl.obolibrary.org/obo/GO_0070842 GO:0021875 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain. go-plus.json fibroblast growth factor receptor signalling pathway in forebrain neuroblast division http://purl.obolibrary.org/obo/GO_0021875 GO:0070843 biolink:BiologicalProcess misfolded protein transport The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0070843 GO:0021876 biolink:BiologicalProcess Notch signaling pathway involved in forebrain neuroblast division The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain. go-plus.json Notch signalling pathway in forebrain neuroblast division http://purl.obolibrary.org/obo/GO_0021876 GO:0070840 biolink:MolecularActivity dynein complex binding Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity. go-plus.json dynein binding http://purl.obolibrary.org/obo/GO_0070840 GO:0021877 biolink:BiologicalProcess forebrain neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021877 GO:0070841 biolink:BiologicalProcess inclusion body assembly The aggregation, arrangement and bonding together of a set of components to form an inclusion body. go-plus.json http://purl.obolibrary.org/obo/GO_0070841 GO:0021878 biolink:BiologicalProcess forebrain astrocyte fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021878 GO:0021879 biolink:BiologicalProcess forebrain neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021879 GO:0006229 biolink:BiologicalProcess dUTP biosynthetic process The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate. go-plus.json dUTP anabolism|dUTP synthesis|dUTP biosynthesis|dUTP formation http://purl.obolibrary.org/obo/GO_0006229 GO:0006227 biolink:BiologicalProcess dUDP biosynthetic process The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate). go-plus.json dUDP synthesis|dUDP biosynthesis|dUDP formation|dUDP anabolism http://purl.obolibrary.org/obo/GO_0006227 GO:0021860 biolink:BiologicalProcess pyramidal neuron development The progression of a pyramidal neuron from its initial formation to its mature state. go-plus.json projection neuron development http://purl.obolibrary.org/obo/GO_0021860 GO:0021861 biolink:BiologicalProcess forebrain radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json radial glial cell differentiation in forebrain http://purl.obolibrary.org/obo/GO_0021861 GO:0006228 biolink:BiologicalProcess UTP biosynthetic process The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate. go-plus.json UTP anabolism|UTP synthesis|UTP formation|UTP biosynthesis http://purl.obolibrary.org/obo/GO_0006228 GO:0006225 biolink:BiologicalProcess UDP biosynthetic process The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate. go-plus.json UDP formation|UDP biosynthesis|UDP anabolism|UDP synthesis http://purl.obolibrary.org/obo/GO_0006225 GO:0021862 biolink:BiologicalProcess early neuron differentiation in forebrain The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021862 GO:0021863 biolink:BiologicalProcess forebrain neuroblast differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json non-surface dividing progenitor cell differentiation|abventricular progenitor cell differentiation|intermediate progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0021863 GO:0006226 biolink:BiologicalProcess dUMP biosynthetic process The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate). go-plus.json dUMP anabolism|dUMP synthesis|dUMP formation|dUMP biosynthesis http://purl.obolibrary.org/obo/GO_0006226 GO:0006223 biolink:BiologicalProcess uracil salvage Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0006223 GO:0006224 biolink:BiologicalProcess obsolete uridine kinase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json uridine kinase reaction http://purl.obolibrary.org/obo/GO_0006224 GO:0006221 biolink:BiologicalProcess pyrimidine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine nucleotide anabolism|pyrimidine nucleotide synthesis|pyrimidine nucleotide formation|pyrimidine nucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0006221 GO:0006222 biolink:BiologicalProcess UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate. go-plus.json UMP anabolism|UMP synthesis|UMP formation|UMP biosynthesis http://purl.obolibrary.org/obo/GO_0006222 GO:0006220 biolink:BiologicalProcess pyrimidine nucleotide metabolic process The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine nucleotide metabolism|pyrimidine metabolic process|pyrimidine metabolism http://purl.obolibrary.org/obo/GO_0006220 GO:0070879 biolink:BiologicalProcess fungal-type cell wall beta-glucan metabolic process The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. go-plus.json fungal-type cell wall beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0070879 GO:0070877 biolink:CellularComponent microprocessor complex A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0070877 GO:0070878 biolink:MolecularActivity primary miRNA binding Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding. go-plus.json pri-miRNA binding|primary microRNA binding http://purl.obolibrary.org/obo/GO_0070878 GO:0021864 biolink:BiologicalProcess obsolete radial glial cell division in forebrain OBSOLETE. The mitotic division of radial glial cells in the developing forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021864 GO:0070875 biolink:BiologicalProcess positive regulation of glycogen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. go-plus.json positive regulation of glycogen metabolism http://purl.obolibrary.org/obo/GO_0070875 GO:0070876 biolink:CellularComponent SOSS complex A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80. go-plus.json http://purl.obolibrary.org/obo/GO_0070876 GO:0021865 biolink:BiologicalProcess obsolete symmetric radial glial cell division in forebrain OBSOLETE. The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021865 GO:0021866 biolink:BiologicalProcess obsolete asymmetric radial glial cell division in forebrain OBSOLETE. The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type. go-plus.json http://purl.obolibrary.org/obo/GO_0021866 GO:0070873 biolink:BiologicalProcess regulation of glycogen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. go-plus.json regulation of glycogen metabolism http://purl.obolibrary.org/obo/GO_0070873 GO:0070874 biolink:BiologicalProcess negative regulation of glycogen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. go-plus.json negative regulation of glycogen metabolism http://purl.obolibrary.org/obo/GO_0070874 GO:0021867 biolink:BiologicalProcess obsolete neuron-producing asymmetric radial glial cell division in forebrain OBSOLETE. The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor. go-plus.json http://purl.obolibrary.org/obo/GO_0021867 GO:0070871 biolink:BiologicalProcess cell wall organization involved in conjugation with cellular fusion A process of cell wall organization that contributes to conjugation with cellular fusion. go-plus.json cell wall organisation involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0070871 GO:0021868 biolink:BiologicalProcess obsolete ventricular zone cell-producing asymmetric radial glial cell division in forebrain OBSOLETE. The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell. go-plus.json http://purl.obolibrary.org/obo/GO_0021868 GO:0070872 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070872 GO:0021869 biolink:BiologicalProcess forebrain ventricular zone progenitor cell division The mitotic division of a basal progenitor giving rise to two neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0021869 GO:0070870 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070870 GO:0006238 biolink:BiologicalProcess CMP salvage Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis. go-plus.json cytidine monophosphate salvage http://purl.obolibrary.org/obo/GO_0006238 GO:0006239 biolink:BiologicalProcess dCMP salvage Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis. go-plus.json deoxycytidine monophosphate salvage http://purl.obolibrary.org/obo/GO_0006239 GO:0021850 biolink:BiologicalProcess subpallium glioblast cell division The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes. go-plus.json glioblast cell division in subpallium|glioblast division in ventral telencephalon http://purl.obolibrary.org/obo/GO_0021850 GO:0021851 biolink:BiologicalProcess neuroblast division in dorsal lateral ganglionic eminence The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb. go-plus.json http://purl.obolibrary.org/obo/GO_0021851 GO:0006236 biolink:BiologicalProcess cytidine salvage Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0006236 GO:0021852 biolink:BiologicalProcess pyramidal neuron migration to cerebral cortex The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. go-plus.json pyramidal neuron migration|projection neuron migration http://purl.obolibrary.org/obo/GO_0021852 GO:0006237 biolink:BiologicalProcess deoxycytidine salvage Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0006237 GO:0006234 biolink:BiologicalProcess TTP biosynthetic process The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate. go-plus.json TTP formation|TTP biosynthesis|TTP anabolism|TTP synthesis http://purl.obolibrary.org/obo/GO_0006234 GO:0006235 biolink:BiologicalProcess dTTP biosynthetic process The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate. go-plus.json dTTP synthesis|dTTP biosynthesis|dTTP formation|dTTP anabolism http://purl.obolibrary.org/obo/GO_0006235 GO:0006232 biolink:BiologicalProcess TDP biosynthetic process The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate. go-plus.json TDP anabolism|TDP synthesis|TDP formation|TDP biosynthesis http://purl.obolibrary.org/obo/GO_0006232 GO:0006233 biolink:BiologicalProcess dTDP biosynthetic process The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate). go-plus.json dTDP anabolism|dTDP synthesis|dTDP biosynthesis|dTDP formation http://purl.obolibrary.org/obo/GO_0006233 GO:0006230 biolink:BiologicalProcess TMP biosynthetic process The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate. go-plus.json TMP biosynthesis|TMP anabolism|TMP synthesis|TMP formation http://purl.obolibrary.org/obo/GO_0006230 GO:0006231 biolink:BiologicalProcess dTMP biosynthetic process The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). go-plus.json dTMP biosynthesis|dTMP anabolism|dTMP synthesis|dTMP formation http://purl.obolibrary.org/obo/GO_0006231 GO:0070868 biolink:BiologicalProcess obsolete heterochromatin organization involved in chromatin silencing OBSOLETE. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing. go-plus.json heterochromatin organisation involved in chromatin silencing http://purl.obolibrary.org/obo/GO_0070868 GO:0070869 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070869 GO:0070866 biolink:MolecularActivity sterol-dependent protein binding Binding to a protein or protein complex in the presence of sterols. go-plus.json http://purl.obolibrary.org/obo/GO_0070866 GO:0070867 biolink:CellularComponent mating projection tip membrane The portion of the plasma membrane surrounding a mating projection tip. go-plus.json mating projection membrane fusion domain|shmoo tip membrane http://purl.obolibrary.org/obo/GO_0070867 GO:0070864 biolink:CellularComponent sperm individualization complex A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst. go-plus.json http://purl.obolibrary.org/obo/GO_0070864 GO:0021853 biolink:BiologicalProcess cerebral cortex GABAergic interneuron migration The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021853 GO:0070865 biolink:CellularComponent investment cone A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization. go-plus.json F-actin cone http://purl.obolibrary.org/obo/GO_0070865 GO:0021854 biolink:BiologicalProcess hypothalamus development The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0021854 GO:0070862 biolink:BiologicalProcess negative regulation of protein exit from endoplasmic reticulum Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum. go-plus.json down regulation of protein exit from endoplasmic reticulum|negative regulation of protein export from endoplasmic reticulum|downregulation of protein exit from endoplasmic reticulum|down-regulation of protein exit from endoplasmic reticulum|negative regulation of protein exit from ER|inhibition of protein exit from endoplasmic reticulum|negative regulation of protein export from ER http://purl.obolibrary.org/obo/GO_0070862 GO:0021855 biolink:BiologicalProcess hypothalamus cell migration The directed movement of a cell into the hypothalamus region of the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021855 GO:0070863 biolink:BiologicalProcess positive regulation of protein exit from endoplasmic reticulum Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum. go-plus.json positive regulation of protein export from ER|positive regulation of protein export from endoplasmic reticulum|up regulation of protein exit from endoplasmic reticulum|activation of protein exit from endoplasmic reticulum|stimulation of protein exit from endoplasmic reticulum|up-regulation of protein exit from endoplasmic reticulum|positive regulation of protein exit from ER|upregulation of protein exit from endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0070863 GO:0021856 biolink:BiologicalProcess hypothalamic tangential migration using cell-axon interactions The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0021856 GO:0070860 biolink:CellularComponent RNA polymerase I core factor complex A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p. go-plus.json http://purl.obolibrary.org/obo/GO_0070860 GO:0021857 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0021857 GO:0070861 biolink:BiologicalProcess regulation of protein exit from endoplasmic reticulum Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum. go-plus.json regulation of protein export from ER|regulation of protein export from endoplasmic reticulum|regulation of protein exit from ER http://purl.obolibrary.org/obo/GO_0070861 GO:0021858 biolink:BiologicalProcess GABAergic neuron differentiation in basal ganglia The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0021858 GO:0021859 biolink:BiologicalProcess pyramidal neuron differentiation The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. go-plus.json projection neuron differentiation http://purl.obolibrary.org/obo/GO_0021859 GO:0006209 biolink:BiologicalProcess cytosine catabolic process The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. go-plus.json cytosine catabolism|cytosine degradation|cytosine breakdown http://purl.obolibrary.org/obo/GO_0006209 GO:0070890 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070890 GO:0006207 biolink:BiologicalProcess 'de novo' pyrimidine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. go-plus.json 'de novo' pyrimidine base anabolism|'de novo' pyrimidine base synthesis|'de novo' pyrimidine base formation|'de novo' pyrimidine base biosynthesis|'de novo' pyrimidine base biosynthetic process http://purl.obolibrary.org/obo/GO_0006207 GO:0006208 biolink:BiologicalProcess pyrimidine nucleobase catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. go-plus.json pyrimidine base catabolism|pyrimidine base catabolic process|pyrimidine base degradation|pyrimidine base breakdown http://purl.obolibrary.org/obo/GO_0006208 GO:0006205 biolink:BiologicalProcess obsolete pyrimidine metabolic process OBSOLETE. (Was not defined before being made obsolete). go-plus.json pyrimidine metabolic process http://purl.obolibrary.org/obo/GO_0006205 GO:0006206 biolink:BiologicalProcess pyrimidine nucleobase metabolic process The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. go-plus.json pyrimidine metabolic process|pyrimidine base metabolism|pyrimidine metabolism|pyrimidine base metabolic process http://purl.obolibrary.org/obo/GO_0006206 GO:0006203 biolink:BiologicalProcess dGTP catabolic process The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate. go-plus.json dGTP catabolism|dGTP degradation|dGTP breakdown http://purl.obolibrary.org/obo/GO_0006203 GO:0021840 biolink:BiologicalProcess directional guidance of interneurons involved in migration from the subpallium to the cortex The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021840 GO:0021841 biolink:BiologicalProcess chemoattraction involved in interneuron migration from the subpallium to the cortex The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex. go-plus.json positive chemotaxis involved in interneuron migration from the subpallium to the cortex http://purl.obolibrary.org/obo/GO_0021841 GO:0006204 biolink:BiologicalProcess IMP catabolic process The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate. go-plus.json IMP degradation|IMP breakdown|IMP catabolism http://purl.obolibrary.org/obo/GO_0006204 GO:0006201 biolink:BiologicalProcess GMP catabolic process to IMP The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate. go-plus.json GMP breakdown to IMP|GMP degradation to IMP http://purl.obolibrary.org/obo/GO_0006201 GO:0006202 biolink:BiologicalProcess GMP catabolic process to guanine The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine. go-plus.json GMP breakdown to guanine|GMP degradation to guanine http://purl.obolibrary.org/obo/GO_0006202 GO:0006200 biolink:BiologicalProcess obsolete ATP catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. Wikipedia:ATP_hydrolysis go-plus.json ATP catabolism|ATP hydrolysis|ATP degradation|ATP breakdown http://purl.obolibrary.org/obo/GO_0006200 GO:0070899 biolink:BiologicalProcess mitochondrial tRNA wobble uridine modification The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified. go-plus.json http://purl.obolibrary.org/obo/GO_0070899 GO:0021842 biolink:BiologicalProcess chemorepulsion involved in interneuron migration from the subpallium to the cortex The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex. go-plus.json negative chemotaxis involved in interneuron migration from the subpallium to the cortex http://purl.obolibrary.org/obo/GO_0021842 GO:0070897 biolink:BiologicalProcess transcription preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription. go-plus.json transcriptional preinitiation complex formation|DNA-templated transcriptional preinitiation complex assembly|transcription PIC biosynthesis|DNA-dependent transcriptional preinitiation complex assembly|transcription PIC formation http://purl.obolibrary.org/obo/GO_0070897 GO:0070898 biolink:BiologicalProcess RNA polymerase III preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter. go-plus.json RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC formation|RNA polymerase III transcriptional preinitiation complex assembly|RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly|RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly|RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC biosynthesis|RNA polymerase III transcriptional preinitiation complex formation http://purl.obolibrary.org/obo/GO_0070898 GO:0021843 biolink:BiologicalProcess substrate-independent telencephalic tangential interneuron migration The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates. go-plus.json http://purl.obolibrary.org/obo/GO_0021843 GO:0021844 biolink:BiologicalProcess interneuron sorting involved in substrate-independent cerebral cortex tangential migration The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures. go-plus.json http://purl.obolibrary.org/obo/GO_0021844 GO:0070895 biolink:BiologicalProcess negative regulation of transposon integration Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. go-plus.json downregulation of transposon integration|down regulation of transposon integration|inhibition of transposon integration|down-regulation of transposon integration http://purl.obolibrary.org/obo/GO_0070895 GO:0070896 biolink:BiologicalProcess positive regulation of transposon integration Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. go-plus.json up regulation of transposon integration|upregulation of transposon integration|stimulation of transposon integration|up-regulation of transposon integration|activation of transposon integration http://purl.obolibrary.org/obo/GO_0070896 GO:0021845 biolink:BiologicalProcess neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner. go-plus.json http://purl.obolibrary.org/obo/GO_0021845 GO:0021846 biolink:BiologicalProcess cell proliferation in forebrain The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021846 GO:0070893 biolink:BiologicalProcess transposon integration Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0070893 GO:0021847 biolink:BiologicalProcess ventricular zone neuroblast division The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially. go-plus.json neuroblast division in ventricular zone http://purl.obolibrary.org/obo/GO_0021847 GO:0070894 biolink:BiologicalProcess regulation of transposon integration Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070894 GO:0021848 biolink:BiologicalProcess neuroblast division in subpallium The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. go-plus.json neuroblast division in the ventral telencephalon http://purl.obolibrary.org/obo/GO_0021848 GO:0070891 biolink:MolecularActivity lipoteichoic acid binding Binding to lipoteichoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070891 GO:0021849 biolink:BiologicalProcess neuroblast division in subventricular zone The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially. go-plus.json http://purl.obolibrary.org/obo/GO_0021849 GO:0070892 biolink:MolecularActivity lipoteichoic acid immune receptor activity Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response. go-plus.json lipoteichoic acid receptor activity http://purl.obolibrary.org/obo/GO_0070892 GO:0006218 biolink:BiologicalProcess uridine catabolic process The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. go-plus.json uridine catabolism|uridine degradation|uridine breakdown http://purl.obolibrary.org/obo/GO_0006218 GO:0006219 biolink:BiologicalProcess deoxyuridine catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA. go-plus.json deoxyuridine degradation|deoxyuridine breakdown|deoxyuridine catabolism http://purl.obolibrary.org/obo/GO_0006219 GO:0006216 biolink:BiologicalProcess cytidine catabolic process The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside. go-plus.json cytidine degradation|cytidine breakdown|cytidine catabolism http://purl.obolibrary.org/obo/GO_0006216 GO:0006217 biolink:BiologicalProcess deoxycytidine catabolic process The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA. go-plus.json deoxycytidine degradation|deoxycytidine catabolism|deoxycytidine breakdown http://purl.obolibrary.org/obo/GO_0006217 GO:0006214 biolink:BiologicalProcess thymidine catabolic process The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. go-plus.json thymidine degradation|deoxyribosylthymine catabolic process|thymidine breakdown|thymidine catabolism|deoxyribosylthymine catabolism http://purl.obolibrary.org/obo/GO_0006214 GO:0006215 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006215 GO:0021830 biolink:BiologicalProcess interneuron migration from the subpallium to the cortex The directed movement of interneurons from the subpallium to the cortex during forebrain development. go-plus.json http://purl.obolibrary.org/obo/GO_0021830 GO:0006212 biolink:BiologicalProcess uracil catabolic process The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. go-plus.json uracil breakdown|uracil catabolism|uracil degradation http://purl.obolibrary.org/obo/GO_0006212 GO:0006213 biolink:BiologicalProcess pyrimidine nucleoside metabolic process The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json pyrimidine nucleoside metabolism|pyrimidine metabolic process|pyrimidine metabolism http://purl.obolibrary.org/obo/GO_0006213 GO:0006210 biolink:BiologicalProcess thymine catabolic process The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. go-plus.json thymine degradation|thymine breakdown|thymine catabolism http://purl.obolibrary.org/obo/GO_0006210 GO:0006211 biolink:BiologicalProcess 5-methylcytosine catabolic process The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA. go-plus.json 5-methylcytosine degradation|5-methylcytosine catabolism|5-methylcytosine breakdown http://purl.obolibrary.org/obo/GO_0006211 GO:0021839 biolink:BiologicalProcess interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021839 GO:0070888 biolink:MolecularActivity E-box binding Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues. go-plus.json E-box promoter binding http://purl.obolibrary.org/obo/GO_0070888 GO:0070889 biolink:BiologicalProcess platelet alpha granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets. go-plus.json platelet alpha granule organization and biogenesis|platelet alpha-granule organization|platelet alpha granule organisation http://purl.obolibrary.org/obo/GO_0070889 GO:0070886 biolink:BiologicalProcess positive regulation of calcineurin-NFAT signaling cascade Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade. go-plus.json upregulation of calcineurin-NFAT signaling cascade|stimulation of calcineurin-NFAT signaling cascade|up-regulation of calcineurin-NFAT signaling cascade|positive regulation of NFAT protein import into nucleus|activation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signaling pathway|up regulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signalling cascade http://purl.obolibrary.org/obo/GO_0070886 GO:0021831 biolink:BiologicalProcess embryonic olfactory bulb interneuron precursor migration The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb. go-plus.json http://purl.obolibrary.org/obo/GO_0021831 GO:0070887 biolink:BiologicalProcess cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0070887 gocheck_do_not_manually_annotate GO:0021832 biolink:BiologicalProcess cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration. go-plus.json http://purl.obolibrary.org/obo/GO_0021832 GO:0070884 biolink:BiologicalProcess regulation of calcineurin-NFAT signaling cascade Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade. go-plus.json NFAT protein import into nucleus|regulation of NFAT protein import into nucleus|regulation of calcineurin-NFAT signalling cascade|regulation of calcineurin-NFAT signaling pathway http://purl.obolibrary.org/obo/GO_0070884 GO:0021833 biolink:BiologicalProcess cell-matrix adhesion involved in tangential migration using cell-cell interactions The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021833 GO:0070885 biolink:BiologicalProcess negative regulation of calcineurin-NFAT signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade. go-plus.json down regulation of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signalling cascade|inhibition of calcineurin-NFAT signaling cascade|negative regulation of NFAT protein import into nucleus|termination of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signaling pathway|down-regulation of calcineurin-NFAT signaling cascade|inhibition of NFAT protein import into nucleus|downregulation of calcineurin-NFAT signaling cascade http://purl.obolibrary.org/obo/GO_0070885 GO:0021834 biolink:BiologicalProcess chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb. go-plus.json negative chemotaxis involved in embryonic olfactory bulb interneuron precursor migration http://purl.obolibrary.org/obo/GO_0021834 GO:0021835 biolink:BiologicalProcess chemoattraction involved in embryonic olfactory bulb interneuron precursor migration The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb. go-plus.json positive chemotaxis involved in embryonic olfactory bulb interneuron precursor migration http://purl.obolibrary.org/obo/GO_0021835 GO:0070882 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070882 GO:0070883 biolink:MolecularActivity pre-miRNA binding Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA. go-plus.json pre-microRNA binding|precursor microRNA binding http://purl.obolibrary.org/obo/GO_0070883 GO:0021836 biolink:BiologicalProcess chemorepulsion involved in postnatal olfactory bulb interneuron migration The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration. go-plus.json negative chemotaxis involved in postnatal olfactory bulb interneuron migration http://purl.obolibrary.org/obo/GO_0021836 GO:0070880 biolink:BiologicalProcess fungal-type cell wall beta-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. go-plus.json fungal-type cell wall beta-glucan biosynthesis|fungal-type cell wall beta-glucan anabolism|fungal-type cell wall beta-glucan synthesis|fungal-type cell wall beta-glucan formation http://purl.obolibrary.org/obo/GO_0070880 GO:0021837 biolink:BiologicalProcess motogenic signaling involved in postnatal olfactory bulb interneuron migration The signaling that results in the stimulation of cell movement in the rostral migratory stream. go-plus.json motogenic signalling involved in postnatal olfactory bulb interneuron migration http://purl.obolibrary.org/obo/GO_0021837 GO:0070881 biolink:BiologicalProcess regulation of proline transport Any process that modulates the frequency, rate or extent of proline transport. go-plus.json http://purl.obolibrary.org/obo/GO_0070881 GO:0021838 biolink:BiologicalProcess motogenic signaling involved in interneuron migration from the subpallium to the cortex The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex. go-plus.json motogenic signalling involved in interneuron migration from the subpallium to the cortex http://purl.obolibrary.org/obo/GO_0021838 CHEBI:71875 biolink:ChemicalSubstance 9-ribosyl-trans-zeatin 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71875 CHEBI:22909 biolink:ChemicalSubstance borate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22909 CHEBI:22907 biolink:ChemicalSubstance bleomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22907 CHEBI:22908 biolink:ChemicalSubstance borate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22908 CHEBI:22901 biolink:ChemicalSubstance bisphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22901 CHEBI:22902 biolink:ChemicalSubstance bisphosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22902 CHEBI:22905 biolink:ChemicalSubstance blasticidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22905 CHEBI:81200 biolink:ChemicalSubstance (S)-corytuberine go-plus.json http://purl.obolibrary.org/obo/CHEBI_81200 chebi_ph7_3 GO:0045806 biolink:BiologicalProcess negative regulation of endocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis. go-plus.json inhibition of endocytosis|down regulation of endocytosis|downregulation of endocytosis|down-regulation of endocytosis http://purl.obolibrary.org/obo/GO_0045806 GO:0031292 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031292 GO:0045807 biolink:BiologicalProcess positive regulation of endocytosis Any process that activates or increases the frequency, rate or extent of endocytosis. go-plus.json up-regulation of endocytosis|upregulation of endocytosis|up regulation of endocytosis|activation of endocytosis|stimulation of endocytosis http://purl.obolibrary.org/obo/GO_0045807 GO:0031293 biolink:BiologicalProcess membrane protein intracellular domain proteolysis The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. go-plus.json membrane protein solubilization http://purl.obolibrary.org/obo/GO_0031293 GO:0045804 biolink:BiologicalProcess negative regulation of eclosion Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion. go-plus.json downregulation of eclosion|down regulation of eclosion|inhibition of eclosion|down-regulation of eclosion http://purl.obolibrary.org/obo/GO_0045804 GO:0031290 biolink:BiologicalProcess retinal ganglion cell axon guidance The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. go-plus.json retinal ganglion cell axon pathfinding http://purl.obolibrary.org/obo/GO_0031290 CHEBI:22918 biolink:ChemicalSubstance branched-chain amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22918 GO:0031291 biolink:BiologicalProcess Ran protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state. go-plus.json http://purl.obolibrary.org/obo/GO_0031291 GO:0045805 biolink:BiologicalProcess positive regulation of eclosion Any process that activates or increases the frequency, rate or extent of eclosion. go-plus.json up regulation of eclosion|upregulation of eclosion|stimulation of eclosion|up-regulation of eclosion|activation of eclosion http://purl.obolibrary.org/obo/GO_0045805 GO:0045802 biolink:BiologicalProcess obsolete negative regulation of cytoskeleton OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton. go-plus.json negative regulation of cytoskeleton http://purl.obolibrary.org/obo/GO_0045802 GO:0045803 biolink:BiologicalProcess obsolete positive regulation of cytoskeleton OBSOLETE. Any process that activates or increases the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton. go-plus.json positive regulation of cytoskeleton http://purl.obolibrary.org/obo/GO_0045803 GO:0045800 biolink:BiologicalProcess negative regulation of chitin-based cuticle tanning Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning. go-plus.json down-regulation of cuticle tanning|negative regulation of cuticle tanning|negative regulation of cuticle hardening|inhibition of cuticle tanning|down regulation of cuticle tanning|downregulation of cuticle tanning http://purl.obolibrary.org/obo/GO_0045800 GO:0045801 biolink:BiologicalProcess positive regulation of chitin-based cuticle tanning Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning. go-plus.json activation of cuticle tanning|positive regulation of cuticle tanning|positive regulation of cuticle hardening|stimulation of cuticle tanning|up-regulation of cuticle tanning|upregulation of cuticle tanning|up regulation of cuticle tanning http://purl.obolibrary.org/obo/GO_0045801 CHEBI:22912 biolink:ChemicalSubstance bornane monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22912 GO:0031298 biolink:CellularComponent replication fork protection complex A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. go-plus.json replisome progression complex|Swi1-Swi3 complex|TIMELESS-TIPIN complex http://purl.obolibrary.org/obo/GO_0031298 GO:0031299 biolink:MolecularActivity taurine-pyruvate aminotransferase activity Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde. MetaCyc:TAURINE-AMINOTRANSFERASE-RXN|EC:2.6.1.77|RHEA:10420|KEGG_REACTION:R05652 go-plus.json taurine:pyruvate aminotransferase activity|Tpa http://purl.obolibrary.org/obo/GO_0031299 GO:0031296 biolink:BiologicalProcess B cell costimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation. go-plus.json B-cell costimulation|B cell co-stimulation|B-lymphocyte costimulation|B-lymphocyte co-stimulation|B-cell co-stimulation|B lymphocyte costimulation|B lymphocyte co-stimulation http://purl.obolibrary.org/obo/GO_0031296 CHEBI:22916 biolink:ChemicalSubstance boron molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_22916 CHEBI:22917 biolink:ChemicalSubstance phytogenic insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22917 GO:0031297 biolink:BiologicalProcess replication fork processing The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes. go-plus.json recovery from replication fork arrest at rDNA locus|replication fork restart|recovery from replication fork stalling at rDNA locus|collapsed replication fork processing|replication fork processing at rDNA locus|replication fork processing at ribosomal DNA locus|recovery from replication fork arrest|replication restart|recovery from replication fork stalling http://purl.obolibrary.org/obo/GO_0031297 GO:0031294 biolink:BiologicalProcess lymphocyte costimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation. go-plus.json lymphocyte co-stimulation http://purl.obolibrary.org/obo/GO_0031294 GO:0045808 biolink:BiologicalProcess negative regulation of establishment of competence for transformation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation. go-plus.json inhibitor of the establishment of competence for transformation activity|downregulation of establishment of competence for transformation|down regulation of establishment of competence for transformation|inhibition of establishment of competence for transformation|down-regulation of establishment of competence for transformation http://purl.obolibrary.org/obo/GO_0045808 GO:0031295 biolink:BiologicalProcess T cell costimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. go-plus.json T lymphocyte costimulation|T cell co-stimulation|T-cell costimulation|T-lymphocyte costimulation|T-cell co-stimulation http://purl.obolibrary.org/obo/GO_0031295 GO:0045809 biolink:BiologicalProcess positive regulation of establishment of competence for transformation Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation. go-plus.json up regulation of establishment of competence for transformation|activator of the establishment of competence for transformation activity|upregulation of establishment of competence for transformation|stimulation of establishment of competence for transformation|up-regulation of establishment of competence for transformation|activation of establishment of competence for transformation http://purl.obolibrary.org/obo/GO_0045809 GO:0045810 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045810 GO:0031281 biolink:BiologicalProcess positive regulation of cyclase activity Any process that activates or increases the activity of a cyclase. go-plus.json upregulation of cyclase activity|stimulation of cyclase activity|up-regulation of cyclase activity|activation of cyclase activity|up regulation of cyclase activity http://purl.obolibrary.org/obo/GO_0031281 GO:0045817 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045817 GO:0045818 biolink:BiologicalProcess negative regulation of glycogen catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. go-plus.json downregulation of glycogen catabolic process|negative regulation of glycogen catabolism|down regulation of glycogen catabolic process|inhibition of glycogen catabolic process|negative regulation of glycogen degradation|negative regulation of glycogen breakdown|down-regulation of glycogen catabolic process|negative regulation of glycogenolysis http://purl.obolibrary.org/obo/GO_0045818 GO:0031282 biolink:BiologicalProcess regulation of guanylate cyclase activity Any process that modulates the frequency, rate or extent of guanylate cyclase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0031282 GO:0045815 biolink:BiologicalProcess positive regulation of gene expression, epigenetic Any epigenetic process that activates or increases the rate of gene expression. go-plus.json up regulation of gene expression, epigenetic|activation of gene expression, epigenetic|stimulation of gene expression, epigenetic|up-regulation of gene expression, epigenetic|upregulation of gene expression, epigenetic|long-term maintenance of gene activation http://purl.obolibrary.org/obo/GO_0045815 GO:0031280 biolink:BiologicalProcess negative regulation of cyclase activity Any process that stops or reduces the activity of a cyclase. go-plus.json inhibition of cyclase activity|down-regulation of cyclase activity|downregulation of cyclase activity|down regulation of cyclase activity http://purl.obolibrary.org/obo/GO_0031280 GO:0045816 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045816 GO:0045813 biolink:BiologicalProcess positive regulation of Wnt signaling pathway, calcium modulating pathway Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). go-plus.json stimulation of frizzled-2 signaling pathway|up-regulation of frizzled-2 signaling pathway|activation of frizzled-2 signaling pathway|positive regulation of frizzled-2 signalling pathway|positive regulation of frizzled-2 signaling pathway|up regulation of frizzled-2 signaling pathway|positive regulation of Wnt-activated signaling pathway, calcium modulating pathway|upregulation of frizzled-2 signaling pathway|positive regulation of Wnt receptor signaling pathway, calcium modulating pathway http://purl.obolibrary.org/obo/GO_0045813 GO:0045814 biolink:BiologicalProcess negative regulation of gene expression, epigenetic Any epigenetic process that stops, prevents or reduces the rate of gene expression. go-plus.json downregulation of gene expression, epigenetic|down-regulation of gene expression, epigenetic|inhibition of gene expression, epigenetic|down regulation of gene expression, epigenetic http://purl.obolibrary.org/obo/GO_0045814 GO:0045811 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045811 GO:0045812 biolink:BiologicalProcess negative regulation of Wnt signaling pathway, calcium modulating pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). go-plus.json negative regulation of frizzled-2 signalling pathway|negative regulation of frizzled-2 signaling pathway|down-regulation of frizzled-2 signaling pathway|downregulation of frizzled-2 signaling pathway|negative regulation of Wnt receptor signaling pathway, calcium modulating pathway|down regulation of frizzled-2 signaling pathway|inhibition of frizzled-2 signaling pathway|negative regulation of Wnt-activated signaling pathway, calcium modulating pathway http://purl.obolibrary.org/obo/GO_0045812 GO:0031289 biolink:BiologicalProcess actin phosphorylation The transfer of one or more phosphate groups to an actin molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031289 GO:0031287 biolink:BiologicalProcess positive regulation of sorocarp stalk cell differentiation Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. go-plus.json up-regulation of stalk cell differentiation|activation of stalk cell differentiation|positive regulation of stalk cell differentiation|up regulation of stalk cell differentiation|upregulation of stalk cell differentiation|stimulation of stalk cell differentiation http://purl.obolibrary.org/obo/GO_0031287 GO:0031288 biolink:BiologicalProcess sorocarp morphogenesis The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum. go-plus.json fruiting body morphogenesis http://purl.obolibrary.org/obo/GO_0031288 GO:0031285 biolink:BiologicalProcess regulation of sorocarp stalk cell differentiation Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. go-plus.json regulation of stalk cell differentiation http://purl.obolibrary.org/obo/GO_0031285 GO:0031286 biolink:BiologicalProcess negative regulation of sorocarp stalk cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. go-plus.json negative regulation of stalk cell differentiation|down-regulation of stalk cell differentiation|downregulation of stalk cell differentiation|down regulation of stalk cell differentiation|inhibition of stalk cell differentiation http://purl.obolibrary.org/obo/GO_0031286 GO:0031283 biolink:BiologicalProcess negative regulation of guanylate cyclase activity Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity. go-plus.json down regulation of guanylate cyclase activity|inhibition of guanylate cyclase activity|down-regulation of guanylate cyclase activity|downregulation of guanylate cyclase activity http://purl.obolibrary.org/obo/GO_0031283 GO:0045819 biolink:BiologicalProcess positive regulation of glycogen catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. go-plus.json upregulation of glycogen catabolic process|stimulation of glycogen catabolic process|up-regulation of glycogen catabolic process|activation of glycogen catabolic process|positive regulation of glycogen degradation|positive regulation of glycogen breakdown|positive regulation of glycogen catabolism|up regulation of glycogen catabolic process|positive regulation of glycogenolysis http://purl.obolibrary.org/obo/GO_0045819 GO:0031284 biolink:BiologicalProcess positive regulation of guanylate cyclase activity Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity. go-plus.json upregulation of guanylate cyclase activity|stimulation of guanylate cyclase activity|up-regulation of guanylate cyclase activity|activation of guanylate cyclase activity|up regulation of guanylate cyclase activity http://purl.obolibrary.org/obo/GO_0031284 GO:0045820 biolink:BiologicalProcess negative regulation of glycolytic process Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis. go-plus.json downregulation of glycolysis|down regulation of glycolysis|inhibition of glycolysis|down-regulation of glycolysis http://purl.obolibrary.org/obo/GO_0045820 GO:0045821 biolink:BiologicalProcess positive regulation of glycolytic process Any process that activates or increases the frequency, rate or extent of glycolysis. go-plus.json up regulation of glycolysis|upregulation of glycolysis|stimulation of glycolysis|up-regulation of glycolysis|activation of glycolysis http://purl.obolibrary.org/obo/GO_0045821 GO:0045828 biolink:BiologicalProcess positive regulation of isoprenoid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. go-plus.json upregulation of isoprenoid metabolic process|stimulation of isoprenoid metabolic process|up-regulation of isoprenoid metabolic process|activation of isoprenoid metabolic process|up regulation of isoprenoid metabolic process|positive regulation of isoprenoid metabolism http://purl.obolibrary.org/obo/GO_0045828 GO:0031270 biolink:BiologicalProcess pseudopodium retraction The myosin-based contraction and retraction of a pseudopodium. go-plus.json http://purl.obolibrary.org/obo/GO_0031270 GO:0045829 biolink:BiologicalProcess negative regulation of isotype switching Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching. go-plus.json negative regulation of isotype switch recombination|down-regulation of isotype switching|inhibition of isotype switching|negative regulation of class switching|down regulation of isotype switching|downregulation of isotype switching|negative regulation of class switch recombination http://purl.obolibrary.org/obo/GO_0045829 GO:0031271 biolink:BiologicalProcess lateral pseudopodium assembly The extension of a pseudopodium from the lateral area of a cell. go-plus.json lateral pseudopodium formation http://purl.obolibrary.org/obo/GO_0031271 GO:0045826 biolink:BiologicalProcess obsolete positive regulation of intermediate filament polymerization and/or depolymerization OBSOLETE. Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization and/or depolymerization. go-plus.json positive regulation of intermediate filament polymerization and/or depolymerization http://purl.obolibrary.org/obo/GO_0045826 GO:0045827 biolink:BiologicalProcess negative regulation of isoprenoid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. go-plus.json down regulation of isoprenoid metabolic process|inhibition of isoprenoid metabolic process|down-regulation of isoprenoid metabolic process|downregulation of isoprenoid metabolic process|negative regulation of isoprenoid metabolism http://purl.obolibrary.org/obo/GO_0045827 GO:0045824 biolink:BiologicalProcess negative regulation of innate immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. go-plus.json down-regulation of innate immune response|downregulation of innate immune response|down regulation of innate immune response|inhibition of innate immune response http://purl.obolibrary.org/obo/GO_0045824 GO:0045825 biolink:BiologicalProcess obsolete negative regulation of intermediate filament polymerization and/or depolymerization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization and/or depolymerization. go-plus.json negative regulation of intermediate filament polymerization and/or depolymerization http://purl.obolibrary.org/obo/GO_0045825 GO:0045822 biolink:BiologicalProcess negative regulation of heart contraction Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. go-plus.json down regulation of heart contraction|downregulation of heart contraction|down-regulation of heart contraction|inhibition of heart contraction|negative regulation of cardiac contraction http://purl.obolibrary.org/obo/GO_0045822 GO:0045823 biolink:BiologicalProcess positive regulation of heart contraction Any process that activates or increases the frequency, rate or extent of heart contraction. go-plus.json upregulation of heart contraction|up regulation of heart contraction|activation of heart contraction|stimulation of heart contraction|up-regulation of heart contraction|positive regulation of cardiac contraction http://purl.obolibrary.org/obo/GO_0045823 GO:0031278 biolink:MolecularActivity alpha-1,2-galactosyltransferase activity Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0031278 GO:0031279 biolink:BiologicalProcess regulation of cyclase activity Any process that modulates the frequency, rate or extent of cyclase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0031279 GO:0031276 biolink:BiologicalProcess obsolete negative regulation of lateral pseudopodium assembly OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell. go-plus.json down-regulation of lateral pseudopodium formation|downregulation of lateral pseudopodium formation|inhibition of lateral pseudopodium formation|negative regulation of lateral pseudopodium formation|down regulation of lateral pseudopodium formation http://purl.obolibrary.org/obo/GO_0031276 GO:0031277 biolink:BiologicalProcess obsolete positive regulation of lateral pseudopodium assembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell. go-plus.json upregulation of lateral pseudopodium formation|stimulation of lateral pseudopodium formation|activation of lateral pseudopodium formation|up-regulation of lateral pseudopodium formation|positive regulation of lateral pseudopodium formation|up regulation of lateral pseudopodium formation http://purl.obolibrary.org/obo/GO_0031277 GO:0031274 biolink:BiologicalProcess positive regulation of pseudopodium assembly Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia. go-plus.json positive regulation of pseudopodium formation|upregulation of pseudopodium formation|stimulation of pseudopodium formation|activation of pseudopodium formation|up-regulation of pseudopodium formation|up regulation of pseudopodium formation http://purl.obolibrary.org/obo/GO_0031274 GO:0031275 biolink:BiologicalProcess obsolete regulation of lateral pseudopodium assembly OBSOLETE. Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell. go-plus.json regulation of lateral pseudopodium formation http://purl.obolibrary.org/obo/GO_0031275 GO:0031272 biolink:BiologicalProcess regulation of pseudopodium assembly Any process that modulates the frequency, rate or extent of the assembly of pseudopodia. go-plus.json regulation of pseudopodium formation http://purl.obolibrary.org/obo/GO_0031272 GO:0031273 biolink:BiologicalProcess negative regulation of pseudopodium assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia. go-plus.json downregulation of pseudopodium formation|inhibition of pseudopodium formation|down regulation of pseudopodium formation|negative regulation of pseudopodium formation|down-regulation of pseudopodium formation http://purl.obolibrary.org/obo/GO_0031273 GO:0031269 biolink:BiologicalProcess pseudopodium assembly The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane. go-plus.json pseudopodium formation|pseudopodium extension http://purl.obolibrary.org/obo/GO_0031269 GO:0045831 biolink:BiologicalProcess negative regulation of light-activated channel activity Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity. go-plus.json down-regulation of light-activated channel activity|downregulation of light-activated channel activity|down regulation of light-activated channel activity|inhibition of light-activated channel activity http://purl.obolibrary.org/obo/GO_0045831 GO:0045832 biolink:BiologicalProcess positive regulation of light-activated channel activity Any process that activates or increases the frequency, rate or extent of light-activated channel activity. go-plus.json stimulation of light-activated channel activity|up-regulation of light-activated channel activity|activation of light-activated channel activity|up regulation of light-activated channel activity|upregulation of light-activated channel activity http://purl.obolibrary.org/obo/GO_0045832 GO:0045830 biolink:BiologicalProcess positive regulation of isotype switching Any process that activates or increases the frequency, rate or extent of isotype switching. go-plus.json up regulation of isotype switching|activation of isotype switching|positive regulation of class switch recombination|stimulation of isotype switching|positive regulation of class switching|positive regulation of isotype switch recombination|up-regulation of isotype switching|upregulation of isotype switching http://purl.obolibrary.org/obo/GO_0045830 GO:0045839 biolink:BiologicalProcess negative regulation of mitotic nuclear division Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. go-plus.json down regulation of mitosis|downregulation of mitosis|negative regulation of mitosis|down-regulation of mitosis|inhibition of mitosis http://purl.obolibrary.org/obo/GO_0045839 GO:0031260 biolink:CellularComponent pseudopodium membrane The portion of the plasma membrane surrounding a pseudopodium. go-plus.json http://purl.obolibrary.org/obo/GO_0031260 GO:0045837 biolink:BiologicalProcess negative regulation of membrane potential Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json reduction of membrane potential|down-regulation of membrane potential|downregulation of membrane potential|down regulation of membrane potential|inhibition of membrane potential http://purl.obolibrary.org/obo/GO_0045837 GO:0045838 biolink:BiologicalProcess positive regulation of membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json elevation of membrane potential|stimulation of membrane potential|up-regulation of membrane potential|activation of membrane potential|up regulation of membrane potential|upregulation of membrane potential http://purl.obolibrary.org/obo/GO_0045838 PR:000007565 biolink:Protein vascular endothelial growth factor receptor 3 A vascular endothelial growth factor receptor that is a translation product of the human FLT4 gene or a 1:1 ortholog thereof. go-plus.json FLT-4|VEGFR-3|tyrosine-protein kinase receptor FLT4|FLT4|Fms-like tyrosine kinase 4 http://purl.obolibrary.org/obo/PR_000007565 GO:0045835 biolink:BiologicalProcess negative regulation of meiotic nuclear division Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. go-plus.json inhibition of meiosis|down regulation of meiosis|downregulation of meiosis|negative regulation of meiosis|down-regulation of meiosis http://purl.obolibrary.org/obo/GO_0045835 GO:0045836 biolink:BiologicalProcess positive regulation of meiotic nuclear division Any process that activates or increases the frequency, rate or extent of meiosis. go-plus.json up-regulation of meiosis|upregulation of meiosis|up regulation of meiosis|activation of meiosis|positive regulation of meiosis|stimulation of meiosis http://purl.obolibrary.org/obo/GO_0045836 GO:0045833 biolink:BiologicalProcess negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. go-plus.json downregulation of lipid metabolic process|negative regulation of lipid metabolism|down-regulation of lipid metabolic process|inhibition of lipid metabolic process|down regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0045833 GO:0045834 biolink:BiologicalProcess positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. go-plus.json up regulation of lipid metabolic process|activation of lipid metabolic process|positive regulation of lipid metabolism|stimulation of lipid metabolic process|up-regulation of lipid metabolic process|upregulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0045834 GO:0031267 biolink:MolecularActivity small GTPase binding Binding to a small monomeric GTPase. go-plus.json Rab interactor activity|Ran protein binding|Rab escort protein activity|Rab GTPase binding|Rac GTPase binding|ADP-ribosylation factor binding|REP|Rho GTPase binding|Ran-binding protein|Ras interactor activity|ARF binding|Ral GTPase binding|GTP-Ral binding|Ran GTPase binding|GTP-Rho binding|Ras GTPase binding http://purl.obolibrary.org/obo/GO_0031267 GO:0031268 biolink:BiologicalProcess pseudopodium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. go-plus.json pseudopodium organization and biogenesis|pseudopodium organisation http://purl.obolibrary.org/obo/GO_0031268 GO:0031265 biolink:CellularComponent CD95 death-inducing signaling complex A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor. go-plus.json Fas death-inducing signaling complex|CD95 death-inducing signalling complex|CD95 DISC http://purl.obolibrary.org/obo/GO_0031265 GO:0031266 biolink:CellularComponent TRAIL death-inducing signaling complex A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor. go-plus.json TRAIL DISC|TRAIL death-inducing signalling complex http://purl.obolibrary.org/obo/GO_0031266 GO:0031263 biolink:MolecularActivity obsolete ATPase-coupled amine transporter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in). go-plus.json amine-transporting ATPase activity|ATP-dependent amine transporter activity|amine ABC transporter http://purl.obolibrary.org/obo/GO_0031263 GO:0031264 biolink:CellularComponent death-inducing signaling complex A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10. Wikipedia:Death-inducing_signaling_complex go-plus.json DISC protein complex|death receptor-induced signalling complex|death-inducing signalling complex|DISC|death receptor-induced signaling complex http://purl.obolibrary.org/obo/GO_0031264 goslim_pir GO:0031261 biolink:CellularComponent DNA replication preinitiation complex A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present. go-plus.json pre-IC http://purl.obolibrary.org/obo/GO_0031261 GO:0031262 biolink:CellularComponent Ndc80 complex An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25. go-plus.json Nuf2-Ndc80 complex http://purl.obolibrary.org/obo/GO_0031262 GO:0031258 biolink:CellularComponent lamellipodium membrane The portion of the plasma membrane surrounding a lamellipodium. go-plus.json http://purl.obolibrary.org/obo/GO_0031258 GO:0031259 biolink:CellularComponent uropod membrane The portion of the plasma membrane surrounding a uropod. go-plus.json uropodium membrane http://purl.obolibrary.org/obo/GO_0031259 GO:0045842 biolink:BiologicalProcess positive regulation of mitotic metaphase/anaphase transition Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. go-plus.json up-regulation of mitotic metaphase/anaphase transition|upregulation of mitotic metaphase/anaphase transition|up regulation of mitotic metaphase/anaphase transition|activation of mitotic metaphase/anaphase transition|stimulation of mitotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_0045842 GO:0045843 biolink:BiologicalProcess negative regulation of striated muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. go-plus.json down-regulation of striated muscle development|inhibition of striated muscle development|down regulation of striated muscle development|downregulation of striated muscle development http://purl.obolibrary.org/obo/GO_0045843 GO:0045840 biolink:BiologicalProcess positive regulation of mitotic nuclear division Any process that activates or increases the frequency, rate or extent of mitosis. go-plus.json mitogenic activity|up-regulation of mitosis|upregulation of mitosis|up regulation of mitosis|activation of mitosis|positive regulation of mitosis|stimulation of mitosis http://purl.obolibrary.org/obo/GO_0045840 GO:0045841 biolink:BiologicalProcess negative regulation of mitotic metaphase/anaphase transition Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. go-plus.json inhibition of mitotic metaphase/anaphase transition|down regulation of mitotic metaphase/anaphase transition|downregulation of mitotic metaphase/anaphase transition|down-regulation of mitotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_0045841 PR:000007581 biolink:Protein fibronectin A protein that is a translation product of the human FN1 gene or a 1:1 ortholog thereof. go-plus.json cold-insoluble globulin|FN1|FN|CIG http://purl.obolibrary.org/obo/PR_000007581 CHEBI:81243 biolink:ChemicalSubstance alpha-muricholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81243 CHEBI:81244 biolink:ChemicalSubstance hyocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81244 GO:0045848 biolink:BiologicalProcess positive regulation of nitrogen utilization Any process that activates or increases the frequency, rate or extent of nitrogen utilization. go-plus.json upregulation of nitrogen utilization|stimulation of nitrogen utilization|up-regulation of nitrogen utilization|activation of nitrogen utilization|up regulation of nitrogen utilization http://purl.obolibrary.org/obo/GO_0045848 GO:0045849 biolink:BiologicalProcess negative regulation of nurse cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process. go-plus.json downregulation of nurse cell apoptosis|down regulation of nurse cell apoptosis|inhibition of nurse cell apoptosis|negative regulation of nurse cell apoptosis|down-regulation of nurse cell apoptosis http://purl.obolibrary.org/obo/GO_0045849 CHEBI:81240 biolink:ChemicalSubstance ursocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81240 GO:0045846 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045846 NCBITaxon:33847 biolink:OrganismalEntity Thalassiosirales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33847 GO:0045847 biolink:BiologicalProcess negative regulation of nitrogen utilization Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization. go-plus.json inhibition of nitrogen utilization|down-regulation of nitrogen utilization|downregulation of nitrogen utilization|down regulation of nitrogen utilization http://purl.obolibrary.org/obo/GO_0045847 GO:0045844 biolink:BiologicalProcess positive regulation of striated muscle tissue development Any process that activates or increases the frequency, rate or extent of striated muscle development. go-plus.json up regulation of striated muscle development|activation of striated muscle development|stimulation of striated muscle development|up-regulation of striated muscle development|upregulation of striated muscle development http://purl.obolibrary.org/obo/GO_0045844 GO:0045845 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045845 NCBITaxon:33846 biolink:OrganismalEntity Thalassiosirophycidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33846 GO:0031256 biolink:CellularComponent leading edge membrane The portion of the plasma membrane surrounding the leading edge of a motile cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031256 GO:0031257 biolink:CellularComponent cell trailing edge membrane The portion of the plasma membrane surrounding the trailing edge of a motile cell. go-plus.json trailing edge membrane http://purl.obolibrary.org/obo/GO_0031257 GO:0031254 biolink:CellularComponent cell trailing edge The area of a motile cell opposite to the direction of movement. go-plus.json trailing edge|back of cell http://purl.obolibrary.org/obo/GO_0031254 goslim_pir GO:0031255 biolink:CellularComponent lateral part of motile cell The area of a motile cell perpendicular to the direction of movement. go-plus.json http://purl.obolibrary.org/obo/GO_0031255 GO:0031252 biolink:CellularComponent cell leading edge The area of a motile cell closest to the direction of movement. go-plus.json front of cell|leading edge of cell http://purl.obolibrary.org/obo/GO_0031252 goslim_pir GO:0031253 biolink:CellularComponent cell projection membrane The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. go-plus.json membrane projection|membrane extension http://purl.obolibrary.org/obo/GO_0031253 GO:0031250 biolink:CellularComponent anaerobic ribonucleoside-triphosphate reductase complex An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0031250 GO:0031251 biolink:CellularComponent PAN complex A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces. go-plus.json poly(A) nuclease complex http://purl.obolibrary.org/obo/GO_0031251 GO:0031249 biolink:MolecularActivity denatured protein binding Binding to a denatured protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031249 GO:0031247 biolink:BiologicalProcess actin rod assembly The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules. go-plus.json actin rod formation http://purl.obolibrary.org/obo/GO_0031247 GO:0031248 biolink:CellularComponent protein acetyltransferase complex A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031248 goslim_pir GO:0006289 biolink:BiologicalProcess nucleotide-excision repair A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). go-plus.json intrastrand cross-link repair|NER|pyrimidine-dimer repair, DNA damage excision http://purl.obolibrary.org/obo/GO_0006289 GO:0045853 biolink:BiologicalProcess negative regulation of bicoid mRNA localization Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location. go-plus.json negative regulation of bicoid mRNA localisation|down-regulation of bicoid mRNA localization|downregulation of bicoid mRNA localization|down regulation of bicoid mRNA localization|inhibition of bicoid mRNA localization http://purl.obolibrary.org/obo/GO_0045853 GO:0045854 biolink:BiologicalProcess positive regulation of bicoid mRNA localization Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location. go-plus.json stimulation of bicoid mRNA localization|up-regulation of bicoid mRNA localization|activation of bicoid mRNA localization|positive regulation of bicoid mRNA localisation|up regulation of bicoid mRNA localization|upregulation of bicoid mRNA localization http://purl.obolibrary.org/obo/GO_0045854 GO:0045851 biolink:BiologicalProcess pH reduction Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion. go-plus.json acidification http://purl.obolibrary.org/obo/GO_0045851 GO:0006287 biolink:BiologicalProcess base-excision repair, gap-filling Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template. go-plus.json http://purl.obolibrary.org/obo/GO_0006287 GO:0045852 biolink:BiologicalProcess pH elevation Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion. go-plus.json http://purl.obolibrary.org/obo/GO_0045852 GO:0006288 biolink:BiologicalProcess base-excision repair, DNA ligation The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair. go-plus.json http://purl.obolibrary.org/obo/GO_0006288 GO:0006285 biolink:BiologicalProcess base-excision repair, AP site formation The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired. go-plus.json http://purl.obolibrary.org/obo/GO_0006285 GO:0045850 biolink:BiologicalProcess positive regulation of nurse cell apoptotic process Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process. go-plus.json positive regulation of nurse cell apoptosis|up regulation of nurse cell apoptosis|upregulation of nurse cell apoptosis|stimulation of nurse cell apoptosis|activation of nurse cell apoptosis|up-regulation of nurse cell apoptosis http://purl.obolibrary.org/obo/GO_0045850 GO:0006286 biolink:BiologicalProcess base-excision repair, base-free sugar-phosphate removal Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0006286 GO:0006283 biolink:BiologicalProcess transcription-coupled nucleotide-excision repair The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway. go-plus.json TC-NER|transcription-coupled NER|transcription-coupled repair|TCR http://purl.obolibrary.org/obo/GO_0006283 GO:0070808 biolink:BiologicalProcess regulation of Hulle cell development Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. go-plus.json http://purl.obolibrary.org/obo/GO_0070808 GO:0006284 biolink:BiologicalProcess base-excision repair In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Wikipedia:Base_excision_repair go-plus.json BER http://purl.obolibrary.org/obo/GO_0006284 GO:0070809 biolink:BiologicalProcess negative regulation of Hulle cell development Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. go-plus.json http://purl.obolibrary.org/obo/GO_0070809 GO:0070817 biolink:BiologicalProcess P-TEFb-cap methyltransferase complex localization Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of P-TEFb-cap methyltransferase complex localization|P-TEFb-cap methyltransferase complex localisation http://purl.obolibrary.org/obo/GO_0070817 GO:0006292 biolink:BiologicalProcess obsolete pyrimidine-dimer repair, DNA damage recognition OBSOLETE. The location of pyrimidine dimers by a large multienzyme complex that scans the DNA for distortions in the double helix caused by pyrimidine dimers. go-plus.json pyrimidine-dimer repair, DNA damage recognition http://purl.obolibrary.org/obo/GO_0006292 GO:0070818 biolink:MolecularActivity protoporphyrinogen oxidase activity Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor. go-plus.json protoporphyrinogenase activity|protoporphyrinogen IX oxidase activity|protoporphyrinogen-IX oxidase activity http://purl.obolibrary.org/obo/GO_0070818 GO:0006293 biolink:BiologicalProcess nucleotide-excision repair, preincision complex stabilization The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_0006293 CHEBI:81253 biolink:ChemicalSubstance isolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81253 GO:0070815 biolink:MolecularActivity peptidyl-lysine 5-dioxygenase activity Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2. go-plus.json peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity|peptide-lysine 5-dioxygenase activity|protein lysine hydroxylase activity|lysyl hydroxylase activity|peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity|lysine hydroxylase activity|lysine-2-oxoglutarate dioxygenase activity|lysine,2-oxoglutarate 5-dioxygenase activity http://purl.obolibrary.org/obo/GO_0070815 GO:0045859 biolink:BiologicalProcess regulation of protein kinase activity Any process that modulates the frequency, rate or extent of protein kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0045859 GO:0006290 biolink:BiologicalProcess pyrimidine dimer repair The repair of UV-induced T-T, C-T and C-C dimers. go-plus.json http://purl.obolibrary.org/obo/GO_0006290 GO:0070816 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex. go-plus.json CTD domain phosphorylation of RNA polymerase II|generation of hyperphosphorylated CTD of RNA polymerase II|hyperphosphorylation of RNA polymerase II C-terminal domain|generation of II(0) form of RNA polymerase II http://purl.obolibrary.org/obo/GO_0070816 GO:0006291 biolink:BiologicalProcess obsolete pyrimidine-dimer repair, DNA damage excision OBSOLETE. The excision of damaged DNA during pyrimidine-dimer repair. A large multienzyme complex scans the DNA for a distortion in the double helix rather than for a specific base change. Once a bulky lesion is found, the phosphodiester backbone of the abnormal strand is cleaved on both sides of the distortion, and the portion of the strand containing the lesion (an oligonucleotide) is peeled away from the DNA double helix by a DNA helicase enzyme. go-plus.json pyrimidine-dimer repair, DNA damage excision http://purl.obolibrary.org/obo/GO_0006291 GO:0045857 biolink:BiologicalProcess negative regulation of molecular function, epigenetic Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya. go-plus.json down-regulation of protein activity, epigenetic|downregulation of protein activity, epigenetic|down regulation of protein activity, epigenetic|inhibition of protein activity, epigenetic|negative regulation of protein activity, epigenetic http://purl.obolibrary.org/obo/GO_0045857 GO:0070813 biolink:BiologicalProcess hydrogen sulfide metabolic process The chemical reactions and pathways involving hydrogen sulfide, H2S. go-plus.json hydrogen sulphide metabolism|hydrogen sulfide metabolism|hydrogen sulphide metabolic process http://purl.obolibrary.org/obo/GO_0070813 NCBITaxon:33836 biolink:OrganismalEntity Coscinodiscophyceae go-plus.json centric diatoms http://purl.obolibrary.org/obo/NCBITaxon_33836 GO:0070814 biolink:BiologicalProcess hydrogen sulfide biosynthetic process The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S. go-plus.json hydrogen sulfide anabolism|hydrogen sulphide biosynthesis|hydrogen sulphide biosynthetic process|hydrogen sulfide synthesis|hydrogen sulfide formation|hydrogen sulfide biosynthesis http://purl.obolibrary.org/obo/GO_0070814 GO:0045858 biolink:BiologicalProcess positive regulation of molecular function, epigenetic Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya. go-plus.json up regulation of protein activity, epigenetic|upregulation of protein activity, epigenetic|stimulation of protein activity, epigenetic|up-regulation of protein activity, epigenetic|positive regulation of protein activity, epigenetic|activation of protein activity, epigenetic http://purl.obolibrary.org/obo/GO_0045858 GO:0070811 biolink:BiologicalProcess glycerol-2-phosphate transmembrane transport The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol. go-plus.json glycerol-2-phosphate transport http://purl.obolibrary.org/obo/GO_0070811 GO:0045855 biolink:BiologicalProcess negative regulation of pole plasm oskar mRNA localization Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. go-plus.json negative regulation of pole plasm oskar mRNA localisation|down-regulation of pole plasm oskar mRNA localization|negative regulation of oocyte pole plasm oskar mRNA localization|downregulation of pole plasm oskar mRNA localization|down regulation of pole plasm oskar mRNA localization|inhibition of pole plasm oskar mRNA localization http://purl.obolibrary.org/obo/GO_0045855 GO:0045856 biolink:BiologicalProcess positive regulation of pole plasm oskar mRNA localization Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. go-plus.json stimulation of pole plasm oskar mRNA localization|up-regulation of pole plasm oskar mRNA localization|activation of pole plasm oskar mRNA localization|positive regulation of oocyte pole plasm oskar mRNA localization|positive regulation of pole plasm oskar mRNA localisation|up regulation of pole plasm oskar mRNA localization|upregulation of pole plasm oskar mRNA localization http://purl.obolibrary.org/obo/GO_0045856 GO:0070812 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070812 GO:0031245 biolink:CellularComponent extrinsic component of periplasmic side of cell outer membrane The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to internal side of cell outer membrane|extrinsic to internal leaflet of cell outer membrane|extrinsic to periplasmic side of cell outer membrane|extrinsic to internal side of outer membrane http://purl.obolibrary.org/obo/GO_0031245 GO:0031246 biolink:CellularComponent intrinsic component of periplasmic side of cell outer membrane The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor. go-plus.json intrinsic to internal side of outer membrane|intrinsic to external side of cell outer membrane|intrinsic to internal side of cell outer membrane|intrinsic to internal leaflet of cell outer membrane http://purl.obolibrary.org/obo/GO_0031246 GO:0070810 biolink:BiologicalProcess positive regulation of Hulle cell development Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. go-plus.json http://purl.obolibrary.org/obo/GO_0070810 GO:0031243 biolink:CellularComponent intrinsic component of external side of cell outer membrane The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor. go-plus.json intrinsic to external side of cell outer membrane|intrinsic to external leaflet of cell outer membrane|intrinsic to external side of outer membrane http://purl.obolibrary.org/obo/GO_0031243 GO:0031244 biolink:CellularComponent extrinsic component of cell outer membrane The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to cell outer membrane http://purl.obolibrary.org/obo/GO_0031244 GO:0031241 biolink:CellularComponent periplasmic side of cell outer membrane The side (leaflet) of the outer membrane that faces the periplasm of the cell. go-plus.json internal leaflet of cell outer membrane|internal side of outer membrane|internal side of cell outer membrane http://purl.obolibrary.org/obo/GO_0031241 GO:0031242 biolink:CellularComponent extrinsic component of external side of cell outer membrane The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to external side of outer membrane|extrinsic to external side of cell outer membrane|extrinsic to external leaflet of cell outer membrane http://purl.obolibrary.org/obo/GO_0031242 GO:0031240 biolink:CellularComponent external side of cell outer membrane The side of the outer membrane that is opposite to the side that faces the periplasm of the cell. go-plus.json external side of outer membrane|external leaflet of cell outer membrane http://purl.obolibrary.org/obo/GO_0031240 GO:0031238 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031238 GO:0031239 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031239 GO:0031236 biolink:CellularComponent extrinsic component of periplasmic side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to external side of plasma membrane, in periplasmic space|extrinsic to external leaflet of plasma membrane, in periplasmic space http://purl.obolibrary.org/obo/GO_0031236 GO:0031237 biolink:CellularComponent intrinsic component of periplasmic side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor. go-plus.json intrinsic to external leaflet of plasma membrane, in periplasmic space|intrinsic to periplasmic side of plasma membrane http://purl.obolibrary.org/obo/GO_0031237 GO:0045864 biolink:BiologicalProcess positive regulation of pteridine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine. go-plus.json up regulation of pteridine metabolic process|activation of pteridine metabolic process|stimulation of pteridine metabolic process|up-regulation of pteridine metabolic process|positive regulation of pteridine metabolism|upregulation of pteridine metabolic process http://purl.obolibrary.org/obo/GO_0045864 GO:0045865 biolink:BiologicalProcess obsolete regulation of recombination within rDNA repeats OBSOLETE. Any process that modulates the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. go-plus.json regulation of recombination within rDNA repeats http://purl.obolibrary.org/obo/GO_0045865 GO:0045862 biolink:BiologicalProcess positive regulation of proteolysis Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. go-plus.json activation of proteolysis|stimulation of proteolysis|up-regulation of proteolysis|upregulation of proteolysis|positive regulation of peptidolysis|up regulation of proteolysis http://purl.obolibrary.org/obo/GO_0045862 GO:0006298 biolink:BiologicalProcess mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. Wikipedia:DNA_mismatch_repair go-plus.json mismatch repair, MutL-like pathway|MMR|long patch mismatch repair system|MutS/MutL/MutH pathway http://purl.obolibrary.org/obo/GO_0006298 PR:000007563 biolink:Protein vascular endothelial growth factor receptor 1 A vascular endothelial growth factor receptor that is a translation product of the human FLT1 gene or a 1:1 ortholog thereof. go-plus.json embryonic receptor kinase 2|FLT-1|tyrosine-protein kinase receptor FLT|Emrk2|FLT|VEGFR-1|tyrosine-protein kinase FRT|FRT|FLT1|vascular permeability factor receptor|Fms-like tyrosine kinase 1 http://purl.obolibrary.org/obo/PR_000007563 GO:0045863 biolink:BiologicalProcess negative regulation of pteridine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine. go-plus.json down regulation of pteridine metabolic process|downregulation of pteridine metabolic process|down-regulation of pteridine metabolic process|negative regulation of pteridine metabolism|inhibition of pteridine metabolic process http://purl.obolibrary.org/obo/GO_0045863 GO:0006299 biolink:BiologicalProcess obsolete short patch mismatch repair system OBSOLETE. The repair of mismatched DNA where the gap to be repaired is only one nucleotide. DNA polymerase is the preferred polymerase in short patch repair, performing gap filling DNA synthesis and removal of the 5'-deoxyribose phosphate of the abasic site. go-plus.json short patch mismatch repair system http://purl.obolibrary.org/obo/GO_0006299 GO:0045860 biolink:BiologicalProcess positive regulation of protein kinase activity Any process that activates or increases the frequency, rate or extent of protein kinase activity. go-plus.json upregulation of protein kinase activity|up regulation of protein kinase activity|stimulation of protein kinase activity|up-regulation of protein kinase activity http://purl.obolibrary.org/obo/GO_0045860 GO:0006296 biolink:BiologicalProcess nucleotide-excision repair, DNA incision, 5'-to lesion The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage. go-plus.json nucleotide-excision repair, DNA incision, 5' to lesion http://purl.obolibrary.org/obo/GO_0006296 GO:0006297 biolink:BiologicalProcess nucleotide-excision repair, DNA gap filling Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes. go-plus.json http://purl.obolibrary.org/obo/GO_0006297 GO:0045861 biolink:BiologicalProcess negative regulation of proteolysis Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. go-plus.json down-regulation of proteolysis|inhibition of proteolysis|negative regulation of peptidolysis|down regulation of proteolysis|downregulation of proteolysis http://purl.obolibrary.org/obo/GO_0045861 GO:0006294 biolink:BiologicalProcess nucleotide-excision repair, preincision complex assembly The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage. go-plus.json nucleotide-excision repair, preincision complex formation http://purl.obolibrary.org/obo/GO_0006294 GO:0006295 biolink:BiologicalProcess nucleotide-excision repair, DNA incision, 3'-to lesion The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage. go-plus.json nucleotide-excision repair, DNA incision, 3' to lesion http://purl.obolibrary.org/obo/GO_0006295 GO:0070806 biolink:BiologicalProcess negative regulation of phialide development Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. go-plus.json http://purl.obolibrary.org/obo/GO_0070806 GO:0070807 biolink:BiologicalProcess positive regulation of phialide development Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. go-plus.json http://purl.obolibrary.org/obo/GO_0070807 GO:0070804 biolink:BiologicalProcess positive regulation of metula development Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. go-plus.json http://purl.obolibrary.org/obo/GO_0070804 GO:0070805 biolink:BiologicalProcess regulation of phialide development Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. go-plus.json http://purl.obolibrary.org/obo/GO_0070805 GO:0045868 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045868 GO:0070802 biolink:BiologicalProcess regulation of metula development Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. go-plus.json http://purl.obolibrary.org/obo/GO_0070802 NCBITaxon:33825 biolink:OrganismalEntity Peniculida go-plus.json Peniculia http://purl.obolibrary.org/obo/NCBITaxon_33825 PR:000007555 biolink:Protein filamin-A A protein that is a translation product of the human FLNA gene or a 1:1 ortholog thereof. go-plus.json FLN1|FLN|filamin-1|FLN-A|actin-binding protein 280|FLNA|endothelial actin-binding protein|ABP-280|non-muscle filamin|alpha-filamin http://purl.obolibrary.org/obo/PR_000007555 GO:0045869 biolink:BiologicalProcess negative regulation of single stranded viral RNA replication via double stranded DNA intermediate Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate. go-plus.json down regulation of retroviral genome replication|downregulation of retroviral genome replication|regulation of retroviral genome replication|down-regulation of retroviral genome replication|negative regulation of retroviral genome replication|inhibition of retroviral genome replication http://purl.obolibrary.org/obo/GO_0045869 GO:0070803 biolink:BiologicalProcess negative regulation of metula development Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. go-plus.json http://purl.obolibrary.org/obo/GO_0070803 PR:000007556 biolink:Protein filamin-B A protein that is a translation product of the human FLNB gene or a 1:1 ortholog thereof. go-plus.json ABP-280 homolog|FLN3|filamin homolog 1|filamin-3|TAP|FLN1L|beta-filamin|FLN-B|thyroid autoantigen|FLNB|ABP-280-like protein|TABP|ABP-278|truncated actin-binding protein|Fh1|truncated ABP|actin-binding-like protein http://purl.obolibrary.org/obo/PR_000007556 GO:0070800 biolink:BiologicalProcess negative regulation of conidiophore stalk development Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. go-plus.json http://purl.obolibrary.org/obo/GO_0070800 GO:0045866 biolink:BiologicalProcess obsolete positive regulation of recombination within rDNA repeats OBSOLETE. Any process that activates or increases the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. go-plus.json positive regulation of recombination within rDNA repeats http://purl.obolibrary.org/obo/GO_0045866 GO:0045867 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045867 PR:000007557 biolink:Protein filamin-C A protein that is a translation product of the human FLNC gene or a 1:1 ortholog thereof. go-plus.json FLN2|filamin-2|FLN-C|FLNC|FLNc|ABPL|ABP-280-like protein|gamma-filamin|ABP-L|actin-binding-like protein http://purl.obolibrary.org/obo/PR_000007557 GO:0070801 biolink:BiologicalProcess positive regulation of conidiophore stalk development Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. go-plus.json http://purl.obolibrary.org/obo/GO_0070801 GO:0031234 biolink:CellularComponent extrinsic component of cytoplasmic side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to internal leaflet of plasma membrane|extrinsic to cytoplasmic side of plasma membrane|extrinsic to internal side of plasma membrane http://purl.obolibrary.org/obo/GO_0031234 GO:0031235 biolink:CellularComponent intrinsic component of the cytoplasmic side of the plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only. go-plus.json intrinsic to internal side of plasma membrane|intrinsic to internal leaflet of plasma membrane|intrinsic to cytoplasmic side of plasma membrane http://purl.obolibrary.org/obo/GO_0031235 GO:0031232 biolink:CellularComponent extrinsic component of external side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to external side of plasma membrane|extrinsic to external leaflet of plasma membrane http://purl.obolibrary.org/obo/GO_0031232 GO:0031233 biolink:CellularComponent intrinsic component of external side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor. go-plus.json intrinsic to external side of plasma membrane|intrinsic to external leaflet of plasma membrane http://purl.obolibrary.org/obo/GO_0031233 GO:0031230 biolink:CellularComponent intrinsic component of cell outer membrane The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to cell outer membrane http://purl.obolibrary.org/obo/GO_0031230 GO:0031231 biolink:CellularComponent intrinsic component of peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to peroxisomal membrane http://purl.obolibrary.org/obo/GO_0031231 CHEBI:22860 biolink:ChemicalSubstance amino-acid betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22860 CHEBI:46832 biolink:ChemicalSubstance 3-carboxypyridine-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46832 CHEBI:46833 biolink:ChemicalSubstance 2-carboxypyridine-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46833 GO:0080193 biolink:BiologicalProcess diffuse secondary thickening Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem. go-plus.json http://purl.obolibrary.org/obo/GO_0080193 UBERON:0003296 biolink:AnatomicalEntity gland of diencephalon Any gland that is part of the diencephalon. Examples: pineal gland, neurohypophysis. go-plus.json interbrain gland|diencephalon gland http://purl.obolibrary.org/obo/UBERON_0003296 UBERON:0003297 biolink:AnatomicalEntity gland of integumental system A gland that is part of a integumental system [Automatically generated definition]. go-plus.json integumentary gland|integumental system gland|integumental gland http://purl.obolibrary.org/obo/UBERON_0003297 UBERON:0003294 biolink:AnatomicalEntity gland of foregut A gland that is part of a foregut [Automatically generated definition]. go-plus.json foregut gland http://purl.obolibrary.org/obo/UBERON_0003294 UBERON:0003295 biolink:AnatomicalEntity pharyngeal gland Racemose mucous glands beneath the mucous membrane of the pharynx. go-plus.json glandulae pharyngeae|pharynx gland http://purl.obolibrary.org/obo/UBERON_0003295 UBERON:0003292 biolink:AnatomicalEntity meninx of spinal cord A meninx that is part of a spinal cord [Automatically generated definition]. go-plus.json spinal meninx|meninges of spinal cord|spinal meninges|spinal cord meninx|spinal cord meninges|menines of spinal cord http://purl.obolibrary.org/obo/UBERON_0003292 GO:0080190 biolink:BiologicalProcess lateral growth Growth of a plant axis (shoot axis or root) that originates from a lateral meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0080190 UBERON:0003290 biolink:AnatomicalEntity meninx of diencephalon A meninx that is part of a diencephalon [Automatically generated definition]. go-plus.json meninx of between brain|meninges of diencephalon|mature diencephalon meninx|mature diencephalon meninges|diencephalon meninx|diencephalon meninges|meninges of mature diencephalon|meninx of mature diencephalon|interbrain meninx|meninx of interbrain|interbrain meninges|between brain meninx|meninges of interbrain|between brain meninges|meninges of between brain http://purl.obolibrary.org/obo/UBERON_0003290 GO:0080191 biolink:BiologicalProcess secondary thickening Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0080191 UBERON:0003291 biolink:AnatomicalEntity meninx of hindbrain A meninx that is part of a hindbrain [Automatically generated definition]. go-plus.json rhomencephalon meninges|hindbrain meninx|meninges of hindbrain|hindbrain meninges http://purl.obolibrary.org/obo/UBERON_0003291 GO:0080192 biolink:BiologicalProcess primary thickening Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0080192 CHEBI:46835 biolink:ChemicalSubstance dipicolinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46835 CHEBI:22869 biolink:ChemicalSubstance bilins go-plus.json http://purl.obolibrary.org/obo/CHEBI_22869 CHEBI:22866 biolink:ChemicalSubstance bilanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_22866 CHEBI:46837 biolink:ChemicalSubstance dipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46837 CHEBI:46838 biolink:ChemicalSubstance cyclic carbonate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_46838 UBERON:0003299 biolink:AnatomicalEntity roof plate of midbrain the mesencephalic roof plate, including the caudal and rostral part of the midbrain roof go-plus.json midbrain roof plate|roofplate of midbrain|midbrain roofplate|roof plate midbrain region|roof plate mesencephalon|roofplate midbrain|roof plate midbrain|midbrain roof http://purl.obolibrary.org/obo/UBERON_0003299 CHEBI:22872 biolink:ChemicalSubstance (glucosyluronic acid)bilirubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22872 CHEBI:46820 biolink:ChemicalSubstance 2,6,8-trihydroxypurin-7-ide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46820 CHEBI:46821 biolink:ChemicalSubstance 6,8-dioxo-6,7,8,9-tetrahydro-1H-purin-2-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46821 CHEBI:46822 biolink:ChemicalSubstance 2,8-dihydroxy-1H-purin-6-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46822 CHEBI:46823 biolink:ChemicalSubstance 1H-purine-2,6,8-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46823 CHEBI:4806 biolink:ChemicalSubstance (-)-epigallocatechin 3-gallate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4806 chebi_ph7_3 GO:0080186 biolink:BiologicalProcess developmental vegetative growth The increase in size or mass of non-reproductive plant parts. go-plus.json http://purl.obolibrary.org/obo/GO_0080186 GO:0080187 biolink:BiologicalProcess floral organ senescence An organ senescence that has as a participant a floral organ. go-plus.json http://purl.obolibrary.org/obo/GO_0080187 GO:0080188 biolink:BiologicalProcess gene silencing by RNA-directed DNA methylation A small RNA-based epigenetic gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism. go-plus.json RNA-directed DNA methylation|RdDM http://purl.obolibrary.org/obo/GO_0080188 GO:0080189 biolink:BiologicalProcess primary growth Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed. go-plus.json http://purl.obolibrary.org/obo/GO_0080189 GO:0080182 biolink:BiologicalProcess histone H3-K4 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0080182 GO:0080183 biolink:BiologicalProcess response to photooxidative stress Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0080183 UBERON:0003283 biolink:AnatomicalEntity mesentery of oesophagus A mesentery that is part of a esophagus [Automatically generated definition]. go-plus.json oesophagus mesentery|meso-esophagus|mesentery of gullet|esophagus mesentery|gullet mesentery|mesentery of esophagus http://purl.obolibrary.org/obo/UBERON_0003283 GO:0080184 biolink:BiologicalProcess response to phenylpropanoid Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin. go-plus.json http://purl.obolibrary.org/obo/GO_0080184 GO:0080185 biolink:BiologicalProcess effector-mediated induction of plant hypersensitive response by symbiont A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes). Wikipedia:Effector-triggered_immunity go-plus.json induction of effector-triggered immunity (ETI)|necrotrophic effector|induction by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|positive regulation by symbiont of plant hypersensitive response|activation by organism of defense response in host by specific elicitors|effector-triggered induction of host innate immune response|induction by symbiont of host resistance gene-dependent defense response|activation by organism of host resistance gene-dependent defense response|ETI-triggered of host innate immune response|positive regulation by organism of defense response in host by specific elicitors|positive regulation by organism of host gene-for-gene resistance|activation of HR|activation by organism of host gene-for-gene resistance|effector-triggered induction of plant hypersensitive response by symbiont|positive regulation by symbiont of plant HR|effector-triggered immunity|ETI triggered of host innate immune response|avirulence protein|induction by organism of defense response in host by specific elicitors|effector-triggered necrosis|activation by symbiont of host resistance gene-dependent defense response|positive regulation by symbiont of host resistance gene-dependent defense response|induction by organism of pathogen-race/host plant cultivar-specific resistance in host|induction by organism of host gene-for-gene resistance|activation of hypersensitive response http://purl.obolibrary.org/obo/GO_0080185 UBERON:0003284 biolink:AnatomicalEntity mesentery of midgut A mesentery that is part of a midgut [Automatically generated definition]. go-plus.json midgut mesentery http://purl.obolibrary.org/obo/UBERON_0003284 UBERON:0003281 biolink:AnatomicalEntity mesentery of stomach The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum. go-plus.json ventriculus mesentery|mesentery of ventriculus|stomach mesentery|mesogastrium|mesogaster|mesogastium http://purl.obolibrary.org/obo/UBERON_0003281 UBERON:0003282 biolink:AnatomicalEntity mesentery of heart A mesentery that surrounds the heart. go-plus.json heart mesentery|mesocardium|cardiac mesentery http://purl.obolibrary.org/obo/UBERON_0003282 GO:0080180 biolink:BiologicalProcess 2-methylguanosine metabolic process The chemical reactions and pathways involving 2-methylguanosine. go-plus.json http://purl.obolibrary.org/obo/GO_0080180 GO:0080181 biolink:BiologicalProcess lateral root branching Any process involved in the formation of branches in lateral roots. go-plus.json http://purl.obolibrary.org/obo/GO_0080181 CHEBI:46824 biolink:ChemicalSubstance 2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46824 CHEBI:46825 biolink:ChemicalSubstance 6-oxo-6,7-dihydro-1H-purine-2,8-diolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46825 CHEBI:46826 biolink:ChemicalSubstance 2,6,8-trioxo-3,6,8,9-tetrahydro-2H-purine-1,7-diide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46826 CHEBI:46827 biolink:ChemicalSubstance carboxypyridinecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46827 UBERON:0003289 biolink:AnatomicalEntity meninx of telencephalon A meninx that is part of a telencephalon [Automatically generated definition]. go-plus.json meninges of telencephalon|telencephalon meninx|telencephalon meninges http://purl.obolibrary.org/obo/UBERON_0003289 CHEBI:46828 biolink:ChemicalSubstance quinolinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46828 UBERON:0003288 biolink:AnatomicalEntity meninx of midbrain A meninx that is part of a midbrain [Automatically generated definition]. go-plus.json mesencephalon meninges|midbrain meninges|meninges of midbrain|midbrain meninx http://purl.obolibrary.org/obo/UBERON_0003288 CHEBI:46811 biolink:ChemicalSubstance 2,6-dihydroxy-7,9-dihydro-8H-purin-8-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_46811 chebi_ph7_3 CHEBI:46812 biolink:ChemicalSubstance 1,3-oxazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_46812 CHEBI:46814 biolink:ChemicalSubstance 9H-purine-2,6,8-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46814 chebi_ph7_3 CHEBI:46817 biolink:ChemicalSubstance 7H-purine-2,6,8-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46817 chebi_ph7_3 UBERON:0003278 biolink:AnatomicalEntity skeleton of lower jaw A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage. go-plus.json lower jaw|mandibles|mandible|lower jaw skeleton|mandibular series http://purl.obolibrary.org/obo/UBERON_0003278 UBERON:0003279 biolink:AnatomicalEntity endothelium of trachea An endothelium that is part of a trachea. go-plus.json trachea endothelium|endothelium of windpipe|windpipe endothelium http://purl.obolibrary.org/obo/UBERON_0003279 CHEBI:46818 biolink:ChemicalSubstance urate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_46818 CHEBI:46819 biolink:ChemicalSubstance urate salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_46819 UBERON:0003277 biolink:AnatomicalEntity skeleton of upper jaw A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones. go-plus.json upper jaw|upper jaw skeleton http://purl.obolibrary.org/obo/UBERON_0003277 CHEBI:46800 biolink:ChemicalSubstance ethanethioic O-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46800 UBERON:0003261 biolink:AnatomicalEntity thyroid primordium endoderm An endoderm that is part of a thyroid primordium. go-plus.json endoderm of thyroid primordium http://purl.obolibrary.org/obo/UBERON_0003261 UBERON:0003260 biolink:AnatomicalEntity endoderm of hindgut An endoderm that is part of a hindgut [Automatically generated definition]. go-plus.json hindgut endoderm http://purl.obolibrary.org/obo/UBERON_0003260 UBERON:0003269 biolink:AnatomicalEntity skeletal muscle tissue of eye A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]. go-plus.json eye skeletal muscle|eye skeletal muscle group|eye skeletal muscle tissue|skeletal muscle tissue of eye http://purl.obolibrary.org/obo/UBERON_0003269 UBERON:0003267 biolink:AnatomicalEntity tooth of upper jaw A calcareous tooth that is part of the upper jaw region. In mammals, the upper jaw teeth are attached to the maxilla. go-plus.json maxillary tooth|upper jaw tooth http://purl.obolibrary.org/obo/UBERON_0003267 UBERON:0003268 biolink:AnatomicalEntity tooth of lower jaw A calcareous tooth that is part of the lower jaw region. In mammals, the lower jaw teeth are attached to the mandible (dentary). go-plus.json lower jaw tooth|calcareous tooth of lower jaw|lower jaw dentine containing tooth|mandibular tooth|lower jaw calcareous tooth|lower jaw vertebrate tooth http://purl.obolibrary.org/obo/UBERON_0003268 UBERON:0003265 biolink:AnatomicalEntity chorionic mesenchyme A mesenchyme that is part of a chorion. go-plus.json chorion mesoderm|mesenchyme of chorion|chorionic mesenchyme|chorion mesenchyme|mesenchyme of chorion (vertebrates) http://purl.obolibrary.org/obo/UBERON_0003265 CHEBI:22823 biolink:ChemicalSubstance beta-alanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_22823 CHEBI:22838 biolink:ChemicalSubstance beta-cyclopiazonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22838 NCBITaxon:9604 biolink:OrganismalEntity Hominidae go-plus.json Pongidae|great apes http://purl.obolibrary.org/obo/NCBITaxon_9604 NCBITaxon:9605 biolink:OrganismalEntity Homo go-plus.json humans http://purl.obolibrary.org/obo/NCBITaxon_9605 NCBITaxon:9606 biolink:OrganismalEntity Homo sapiens go-plus.json human|man http://purl.obolibrary.org/obo/NCBITaxon_9606 NCBITaxon:9608 biolink:OrganismalEntity Canidae go-plus.json dog, coyote, wolf, fox http://purl.obolibrary.org/obo/NCBITaxon_9608 NCBITaxon:9611 biolink:OrganismalEntity Canis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9611 NCBITaxon:9612 biolink:OrganismalEntity Canis lupus go-plus.json grey wolf|gray wolf http://purl.obolibrary.org/obo/NCBITaxon_9612 CHEBI:22801 biolink:ChemicalSubstance beta-D-glucosyl-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22801 chebi_ph7_3 CHEBI:4828 biolink:ChemicalSubstance ergothioneine go-plus.json http://purl.obolibrary.org/obo/CHEBI_4828 NCBITaxon:9615 biolink:OrganismalEntity Canis lupus familiaris go-plus.json Canis domesticus|dog|dogs|Canis familiaris|Canis canis http://purl.obolibrary.org/obo/NCBITaxon_9615 GO:0031193 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031193 GO:0031194 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031194 GO:0031191 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031191 GO:0031192 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031192 GO:0031190 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031190 GO:0031199 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031199 GO:0031197 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031197 GO:0031198 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031198 GO:0031195 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031195 GO:0031196 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031196 GO:0070790 biolink:BiologicalProcess phialide development The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips. go-plus.json development of secondary sterigmata http://purl.obolibrary.org/obo/GO_0070790 GO:0070791 biolink:BiologicalProcess cleistothecium development The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. go-plus.json http://purl.obolibrary.org/obo/GO_0070791 GO:0080117 biolink:BiologicalProcess secondary growth Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium. go-plus.json cambial secondary growth http://purl.obolibrary.org/obo/GO_0080117 GO:0080118 biolink:MolecularActivity brassinosteroid sulfotransferase activity Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0080118 GO:0080119 biolink:BiologicalProcess ER body organization A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species. go-plus.json ER body organization and biogenesis|ER body organisation|endoplasmic reticulum body organization and biogenesis|endoplasmic reticulum body organization http://purl.obolibrary.org/obo/GO_0080119 GO:0080113 biolink:BiologicalProcess regulation of seed growth Any process that modulates the frequency, rate or extent of growth of the seed of an plant. go-plus.json regulation of seed size http://purl.obolibrary.org/obo/GO_0080113 GO:0080114 biolink:BiologicalProcess positive regulation of glycine hydroxymethyltransferase activity Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0080114 GO:0080115 biolink:MolecularActivity myosin XI tail binding Binding to the tail region of a myosin XI heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0080115 GO:0080116 biolink:MolecularActivity glucuronoxylan glucuronosyltransferase activity Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080116 GO:0080110 biolink:BiologicalProcess sporopollenin biosynthetic process The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer. go-plus.json sporopollenin biosynthesis http://purl.obolibrary.org/obo/GO_0080110 GO:0080111 biolink:BiologicalProcess DNA demethylation The removal of a methyl group from one or more nucleotides within an DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0080111 GO:0080112 biolink:BiologicalProcess seed growth The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0080112 GO:0021828 biolink:BiologicalProcess gonadotrophin-releasing hormone neuronal migration to the hypothalamus The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus. go-plus.json gonadotropin-releasing hormone neuronal migration to the hypothalamus http://purl.obolibrary.org/obo/GO_0021828 GO:0021829 biolink:BiologicalProcess oligodendrocyte cell migration from the subpallium to the cortex The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development. go-plus.json http://purl.obolibrary.org/obo/GO_0021829 UBERON:0003216 biolink:AnatomicalEntity hard palate Anterior portion of the palate consisting of bone and mucous membranes[GO]. The hard palate is formed from bony processes of the maxilla, premaxilla and palatine[Kardong]. go-plus.json palatum durum|hard palate http://purl.obolibrary.org/obo/UBERON_0003216 GO:0070798 biolink:BiologicalProcess positive regulation of cleistothecium development Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. go-plus.json http://purl.obolibrary.org/obo/GO_0070798 GO:0021820 biolink:BiologicalProcess extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells. go-plus.json organization of extracellular matrix in the marginal zone involved in cerebral cortex glial-mediated radial migration|extracellular matrix organisation in marginal zone involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0021820 GO:0021821 biolink:BiologicalProcess negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. go-plus.json inhibition of cell-glial cell adhesion involved in cerebral cortex lamination|down regulation of cell-glial cell adhesion involved in cerebral cortex lamination|downregulation of cell-glial cell adhesion involved in cerebral cortex lamination|down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination http://purl.obolibrary.org/obo/GO_0021821 GO:0070799 biolink:BiologicalProcess regulation of conidiophore stalk development Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. go-plus.json http://purl.obolibrary.org/obo/GO_0070799 UBERON:0003214 biolink:AnatomicalEntity mammary gland alveolus A sac-like structure that is found in the mature gland[GO]. go-plus.json alveolus of mammary gland|lactiferous gland alveolus|mammary alveoli|mammary alveolus|lobe of mammary gland alveolus|alveolus of lobe of breast|lobe of breast alveolus|alveolus of lobe of mammary gland|lactiferous alveolus|alveolus of lactiferous gland http://purl.obolibrary.org/obo/UBERON_0003214 GO:0021822 biolink:BiologicalProcess negative regulation of cell motility involved in cerebral cortex radial glia guided migration The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. go-plus.json down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration|negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration|downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration http://purl.obolibrary.org/obo/GO_0021822 GO:0070796 biolink:BiologicalProcess regulation of cleistothecium development Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. go-plus.json http://purl.obolibrary.org/obo/GO_0070796 GO:0021823 biolink:BiologicalProcess cerebral cortex tangential migration using cell-cell interactions The process in which neurons interact with each other to promote migration along a tangential plane. go-plus.json chain migration http://purl.obolibrary.org/obo/GO_0021823 UBERON:0003215 biolink:AnatomicalEntity alveolus organ part that has the form of a hollow cavity[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003215 GO:0070797 biolink:BiologicalProcess negative regulation of cleistothecium development Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. go-plus.json http://purl.obolibrary.org/obo/GO_0070797 UBERON:0003212 biolink:AnatomicalEntity gustatory organ Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912). go-plus.json taste organ|organ of gustatory organ system|gustatory organ system organ|organ of gustatory system|organ of taste system|gustatory system organ|taste system organ http://purl.obolibrary.org/obo/UBERON_0003212 GO:0070794 biolink:BiologicalProcess negative regulation of conidiophore development Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. go-plus.json http://purl.obolibrary.org/obo/GO_0070794 GO:0021824 biolink:BiologicalProcess cerebral cortex tangential migration using cell-axon interactions The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0021824 GO:0021825 biolink:BiologicalProcess substrate-dependent cerebral cortex tangential migration The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions. go-plus.json http://purl.obolibrary.org/obo/GO_0021825 GO:0070795 biolink:BiologicalProcess positive regulation of conidiophore development Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. go-plus.json http://purl.obolibrary.org/obo/GO_0070795 UBERON:0003210 biolink:AnatomicalEntity blood-cerebrospinal fluid barrier barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]. go-plus.json blood-CSF barrier http://purl.obolibrary.org/obo/UBERON_0003210 GO:0021826 biolink:BiologicalProcess substrate-independent telencephalic tangential migration The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact. go-plus.json http://purl.obolibrary.org/obo/GO_0021826 GO:0070792 biolink:BiologicalProcess Hulle cell development The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. go-plus.json Huelle cell development|Hulle cell formation http://purl.obolibrary.org/obo/GO_0070792 GO:0070793 biolink:BiologicalProcess regulation of conidiophore development Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. go-plus.json http://purl.obolibrary.org/obo/GO_0070793 GO:0021827 biolink:BiologicalProcess postnatal olfactory bulb interneuron migration The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth. go-plus.json http://purl.obolibrary.org/obo/GO_0021827 GO:0070780 biolink:MolecularActivity dihydrosphingosine-1-phosphate phosphatase activity Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate. MetaCyc:RXN3DJ-25|RHEA:27514|Reactome:R-HSA-428664 go-plus.json sphinganine-1-phosphate phosphatase activity|dihydrosphingosine-1-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0070780 GO:0080106 biolink:MolecularActivity 7-methylthiopropyl glucosinolate S-oxygenase activity Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate. go-plus.json http://purl.obolibrary.org/obo/GO_0080106 GO:0080107 biolink:MolecularActivity 8-methylthiopropyl glucosinolate S-oxygenase activity Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate. go-plus.json http://purl.obolibrary.org/obo/GO_0080107 GO:0080108 biolink:MolecularActivity S-alkylthiohydroximate lyase activity Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate. go-plus.json S-alkylthiohydroximate C-S lyase activity http://purl.obolibrary.org/obo/GO_0080108 GO:0080109 biolink:MolecularActivity indole-3-acetonitrile nitrile hydratase activity Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide. KEGG_REACTION:R04020|MetaCyc:RXN-7567|EC:4.2.1.84 go-plus.json http://purl.obolibrary.org/obo/GO_0080109 GO:0080102 biolink:MolecularActivity 3-methylthiopropyl glucosinolate S-oxygenase activity Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate. MetaCyc:RXN-2221 go-plus.json http://purl.obolibrary.org/obo/GO_0080102 GO:0080103 biolink:MolecularActivity 4-methylthiopropyl glucosinolate S-oxygenase activity Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate. go-plus.json http://purl.obolibrary.org/obo/GO_0080103 GO:0080104 biolink:MolecularActivity 5-methylthiopropyl glucosinolate S-oxygenase activity Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate. go-plus.json http://purl.obolibrary.org/obo/GO_0080104 GO:0080105 biolink:MolecularActivity 6-methylthiopropyl glucosinolate S-oxygenase activity Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate. go-plus.json http://purl.obolibrary.org/obo/GO_0080105 GO:0080100 biolink:MolecularActivity L-glutamine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate. EC:2.6.1.50 go-plus.json L-glutamine:alpha-ketoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0080100 GO:0080101 biolink:MolecularActivity phosphatidyl-N-dimethylethanolamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine. RHEA:32739|MetaCyc:RXN4FS-2|EC:2.1.1.71|KEGG_REACTION:R01320 go-plus.json http://purl.obolibrary.org/obo/GO_0080101 GO:0021817 biolink:BiologicalProcess nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration. go-plus.json nucleokinesis involved in cell locomotion in cerebral cortex glial-mediated radial migration|nucleokinesis involved in cell locomotion in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0021817 NCBITaxon:9682 biolink:OrganismalEntity Felis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9682 CHEBI:32274 biolink:ChemicalSubstance UDP-3-keto-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_32274 GO:0021818 biolink:BiologicalProcess modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. go-plus.json modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021818 CHEBI:32275 biolink:ChemicalSubstance UDP-alpha-D-kanosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32275 GO:0021819 biolink:BiologicalProcess layer formation in cerebral cortex The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. go-plus.json cerebral cortex lamination http://purl.obolibrary.org/obo/GO_0021819 NCBITaxon:9685 biolink:OrganismalEntity Felis catus go-plus.json Felis domesticus|cats|cat|domestic cat|Felis silvestris catus http://purl.obolibrary.org/obo/NCBITaxon_9685 CHEBI:4885 biolink:ChemicalSubstance ethionamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_4885 chebi_ph7_3 GO:0070789 biolink:BiologicalProcess metula development The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. go-plus.json development of primary sterigmata http://purl.obolibrary.org/obo/GO_0070789 GO:0070787 biolink:BiologicalProcess conidiophore development The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. go-plus.json http://purl.obolibrary.org/obo/GO_0070787 GO:0021810 biolink:BiologicalProcess neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration. go-plus.json neurotransmitter signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021810 GO:0070788 biolink:BiologicalProcess conidiophore stalk development The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. go-plus.json http://purl.obolibrary.org/obo/GO_0070788 GO:0070785 biolink:BiologicalProcess negative regulation of growth of unicellular organism as a thread of attached cells Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium. go-plus.json http://purl.obolibrary.org/obo/GO_0070785 GO:0021811 biolink:BiologicalProcess growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex. go-plus.json growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration|growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021811 GO:0070786 biolink:BiologicalProcess positive regulation of growth of unicellular organism as a thread of attached cells Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium. go-plus.json http://purl.obolibrary.org/obo/GO_0070786 GO:0021812 biolink:BiologicalProcess neuronal-glial interaction involved in cerebral cortex radial glia guided migration The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. go-plus.json neuronal-glial interaction involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021812 GO:0021813 biolink:BiologicalProcess cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex. go-plus.json cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021813 GO:0070783 biolink:BiologicalProcess growth of unicellular organism as a thread of attached cells A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0070783 goslim_candida GO:0070784 biolink:BiologicalProcess regulation of growth of unicellular organism as a thread of attached cells Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium. go-plus.json http://purl.obolibrary.org/obo/GO_0070784 GO:0021814 biolink:BiologicalProcess cell motility involved in cerebral cortex radial glia guided migration The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. go-plus.json cell locomotion involved in cerebral cortex radial glia guided migration|cell locomotion involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021814 GO:0070781 biolink:BiologicalProcess response to biotin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus. go-plus.json response to vitamin H|response to Bios IIB|response to vitamin B7|response to coenzyme R http://purl.obolibrary.org/obo/GO_0070781 GO:0021815 biolink:BiologicalProcess modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. go-plus.json modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021815 GO:0070782 biolink:BiologicalProcess phosphatidylserine exposure on apoptotic cell surface A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity. go-plus.json externalization of phosphatidylserine http://purl.obolibrary.org/obo/GO_0070782 GO:0021816 biolink:BiologicalProcess extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021816 NCBITaxon:9681 biolink:OrganismalEntity Felidae go-plus.json cat family http://purl.obolibrary.org/obo/NCBITaxon_9681 CHEBI:46895 biolink:ChemicalSubstance lipopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46895 CHEBI:46896 biolink:ChemicalSubstance diacyl lipopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46896 GO:0080139 biolink:MolecularActivity borate efflux transmembrane transporter activity Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane. go-plus.json boron efflux transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0080139 CHEBI:46898 biolink:ChemicalSubstance cholesteryl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46898 chebi_ph7_3 GO:0080135 biolink:BiologicalProcess regulation of cellular response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0080135 GO:0080136 biolink:BiologicalProcess priming of cellular response to stress The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress. go-plus.json priming of stress response|priming of response to stress http://purl.obolibrary.org/obo/GO_0080136 GO:0080137 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080137 GO:0080138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080138 GO:0080131 biolink:MolecularActivity hydroxyjasmonate sulfotransferase activity Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate. go-plus.json OHJA sulfotransferase activity|12-hydroxyjasmonic acid sulfotransferase activity|11-hydroxyjasmonic acid sulfotransferase activity|hydroxyjasmonic acid sulfotransferase activity|12-hydroxyjasmonate sulfotransferase activity|12-OHJA sulfotransferase activity|11-hydroxyjasmonate sulfotransferase activity|11-OHJA sulfotransferase activity http://purl.obolibrary.org/obo/GO_0080131 GO:0080132 biolink:MolecularActivity fatty acid alpha-hydroxylase activity Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain. Reactome:R-HSA-5693761 go-plus.json fatty acid 2-hydroxylase http://purl.obolibrary.org/obo/GO_0080132 CHEBI:46890 biolink:ChemicalSubstance silicon hydroxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46890 OBO:uberon/core#trunk_part_of biolink:OntologyClass trunk_part_of trunk_part_of go-plus.json http://purl.obolibrary.org/obo/uberon/core#trunk_part_of GO:0080133 biolink:MolecularActivity midchain alkane hydroxylase activity Catalysis of the conversion of an alkane to a secondary alcohol. go-plus.json http://purl.obolibrary.org/obo/GO_0080133 CHEBI:46891 biolink:ChemicalSubstance azetidinecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46891 GO:0080134 biolink:BiologicalProcess regulation of response to stress Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0080134 gocheck_do_not_manually_annotate GO:0021806 biolink:BiologicalProcess initiation of movement involved in cerebral cortex radial glia guided migration The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex. go-plus.json initiation of movement involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021806 GO:0021807 biolink:BiologicalProcess motogenic signaling initiating cell movement in cerebral cortex The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex. go-plus.json motogenic signalling initiating cell movement in the cerebral cortex http://purl.obolibrary.org/obo/GO_0021807 GO:0021808 biolink:BiologicalProcess cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration. go-plus.json cytosolic calcium signalling involved in the initiation of cell movement in glial-mediated radial cell migration http://purl.obolibrary.org/obo/GO_0021808 GO:0080130 biolink:MolecularActivity L-phenylalanine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate. KEGG_REACTION:R00694|MetaCyc:RXN-10814|RHEA:25152|MetaCyc:PHEAMINOTRANS-RXN|EC:2.6.1.57 go-plus.json L-phenylalanine:alpha-ketoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0080130 GO:0021809 biolink:BiologicalProcess neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration. go-plus.json neurotrophic factor signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration http://purl.obolibrary.org/obo/GO_0021809 GO:0021800 biolink:BiologicalProcess cerebral cortex tangential migration The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. go-plus.json http://purl.obolibrary.org/obo/GO_0021800 GO:0021801 biolink:BiologicalProcess cerebral cortex radial glia-guided migration The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. go-plus.json glial-guided locomotion|cerebral cortex radial glia-dependent cell migration|cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0021801 GO:0021802 biolink:BiologicalProcess somal translocation The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate. go-plus.json perikaryal translocation of Morest http://purl.obolibrary.org/obo/GO_0021802 GO:0021803 biolink:BiologicalProcess extension of leading cell process to pial surface The extension of a long process to the pial surface as a cell leaves the ventricular zone. go-plus.json http://purl.obolibrary.org/obo/GO_0021803 GO:0021804 biolink:BiologicalProcess negative regulation of cell adhesion in ventricular zone The process that results in the loss of attachments of a cell in the ventricular zone. go-plus.json inhibition of cell adhesion in ventricular zone|down regulation of cell adhesion in ventricular zone|downregulation of cell adhesion in ventricular zone|down-regulation of cell adhesion in ventricular zone http://purl.obolibrary.org/obo/GO_0021804 GO:0021805 biolink:BiologicalProcess cell movement involved in somal translocation The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface. go-plus.json cell motility involved in somal translocation http://purl.obolibrary.org/obo/GO_0021805 CHEBI:46883 biolink:ChemicalSubstance carboxy group go-plus.json http://purl.obolibrary.org/obo/CHEBI_46883 GO:0080128 biolink:BiologicalProcess anther septum development The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone. go-plus.json http://purl.obolibrary.org/obo/GO_0080128 GO:0080129 biolink:BiologicalProcess proteasome core complex assembly The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles. go-plus.json 20S proteasome assembly http://purl.obolibrary.org/obo/GO_0080129 GO:0080124 biolink:MolecularActivity pheophytinase activity Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide. go-plus.json pheophytin pheophorbide hydrolase activity http://purl.obolibrary.org/obo/GO_0080124 GO:0080125 biolink:BiologicalProcess obsolete multicellular structure septum development OBSOLETE. The process whose specific outcome is the progression of the multicellular structure septum over time, from its formation to the mature structure. The multicellular structure septum is the thin partition or membrane that divides a cavity or a mass of tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0080125 GO:0080126 biolink:BiologicalProcess ovary septum development The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s). go-plus.json http://purl.obolibrary.org/obo/GO_0080126 GO:0080127 biolink:BiologicalProcess fruit septum development The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit. go-plus.json http://purl.obolibrary.org/obo/GO_0080127 GO:0080120 biolink:BiologicalProcess CAAX-box protein maturation A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase. go-plus.json farnesylated protein maturation|CAAX-box protein processing http://purl.obolibrary.org/obo/GO_0080120 GO:0080121 biolink:BiologicalProcess AMP transport The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json adenosine monophosphate transport http://purl.obolibrary.org/obo/GO_0080121 GO:0080122 biolink:MolecularActivity AMP transmembrane transporter activity Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other. go-plus.json adenosine monophosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0080122 GO:0080123 biolink:MolecularActivity jasmonate-amino synthetase activity Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate). go-plus.json jasmonate:amino acid synthetase activity|jasmonyl-amino synthetase activity|jasmonate-amino acid synthetase activity|ja-amino synthetase activity|jasmonic acid-amino synthetase activity|jasmonate-amino acid conjugate synthetase activity|jasmonate-amido synthetase activity http://purl.obolibrary.org/obo/GO_0080123 CHEBI:4866 biolink:ChemicalSubstance 17beta-estradiol 3-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4866 CHEBI:46874 biolink:ChemicalSubstance alpha-amino acid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_46874 GO:0080157 biolink:BiologicalProcess regulation of plant-type cell wall organization or biogenesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall. go-plus.json regulation of plant-type cell wall organisation or biogenesis http://purl.obolibrary.org/obo/GO_0080157 GO:0080158 biolink:BiologicalProcess obsolete chloroplast ribulose bisphosphate carboxylase complex biogenesis OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a chloroplast ribulose bisphosphate carboxylase (RubisCO) complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. go-plus.json http://purl.obolibrary.org/obo/GO_0080158 GO:0080159 biolink:BiologicalProcess zygote elongation The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0080159 GO:0080153 biolink:BiologicalProcess negative regulation of reductive pentose-phosphate cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle. go-plus.json negative regulation of C3 photosynthesis|negative regulation of Calvin cycle http://purl.obolibrary.org/obo/GO_0080153 GO:0080154 biolink:BiologicalProcess regulation of fertilization Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). go-plus.json http://purl.obolibrary.org/obo/GO_0080154 GO:0080155 biolink:BiologicalProcess regulation of double fertilization forming a zygote and endosperm Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0080155 GO:0080156 biolink:BiologicalProcess mitochondrial mRNA modification The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically. go-plus.json mitochondrial mRNA editing|mitochondrial RNA editing http://purl.obolibrary.org/obo/GO_0080156 UBERON:0003252 biolink:AnatomicalEntity thoracic rib cage Subdivision of skeletal system that consists of all ribs in an organism connected to the sternum and the vertebrae. Some vertebrates have abdominal ribs (gastrialia), not connected to the vertebrate - these are not considered part of the rib case. go-plus.json rib cage|cavea thoracis|cavea thoracis|thoracic cage http://purl.obolibrary.org/obo/UBERON_0003252 UBERON:0003253 biolink:AnatomicalEntity neck of rib The neck of the rib is the flattened portion which extends lateralward from the head; it is about 2.5 cm. long, and is placed in front of the transverse process of the lower of the two vertebrC& with which the head articulates. Its anterior surface is flat and smooth, its posterior rough for the attachment of the ligament of the neck, and perforated by numerous foramina. Of its two borders the superior presents a rough crest (crista colli costE) for the attachment of the anterior costotransverse ligament; its inferior border is rounded. On the posterior surface at the junction of the neck and body, and nearer the lower than the upper border, is an eminencebthe tubercle; it consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrC& to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs. go-plus.json rib neck|collum costae|collum costae http://purl.obolibrary.org/obo/UBERON_0003253 GO:0080150 biolink:MolecularActivity S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine. RHEA:36099|MetaCyc:RXN-6722 go-plus.json S-adenosyl-L-methionine:benzoate carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0080150 GO:0080151 biolink:BiologicalProcess positive regulation of salicylic acid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction. go-plus.json positive regulation of salicylic acid mediated signalling pathway http://purl.obolibrary.org/obo/GO_0080151 GO:0080152 biolink:BiologicalProcess regulation of reductive pentose-phosphate cycle Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle. go-plus.json regulation of Calvin cycle|regulation of C3 photosynthesis http://purl.obolibrary.org/obo/GO_0080152 UBERON:0003258 biolink:AnatomicalEntity endoderm of foregut An endoderm that is part of a foregut [Automatically generated definition]. go-plus.json foregut endoderm http://purl.obolibrary.org/obo/UBERON_0003258 UBERON:0003259 biolink:AnatomicalEntity endoderm of midgut An endoderm that is part of a midgut [Automatically generated definition]. go-plus.json midgut endoderm http://purl.obolibrary.org/obo/UBERON_0003259 UBERON:0003257 biolink:AnatomicalEntity yolk sac endoderm The portion of the yolk sac that is derived from endoderm and lines the yolk sac. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003257 NCBITaxon:403667 biolink:OrganismalEntity Vitales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_403667 CHEBI:46860 biolink:ChemicalSubstance cinchomeronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46860 CHEBI:46861 biolink:ChemicalSubstance cinchomeronate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46861 chebi_ph7_3 CHEBI:46862 biolink:ChemicalSubstance cinchomeronate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46862 CHEBI:46863 biolink:ChemicalSubstance 4-carboxypyridine-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46863 CHEBI:46864 biolink:ChemicalSubstance 3-carboxypyridine-4-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46864 CHEBI:46867 biolink:ChemicalSubstance indolyl carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46867 GO:0080146 biolink:MolecularActivity L-cysteine desulfhydrase activity Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+. MetaCyc:LCYSDESULF-RXN|RHEA:24931|EC:4.4.1.1|Reactome:R-HSA-1614591|Reactome:R-HSA-1614614 go-plus.json http://purl.obolibrary.org/obo/GO_0080146 GO:0080147 biolink:BiologicalProcess root hair cell development The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0080147 GO:0080148 biolink:BiologicalProcess negative regulation of response to water deprivation Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. go-plus.json http://purl.obolibrary.org/obo/GO_0080148 GO:0080149 biolink:BiologicalProcess sucrose induced translational repression Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level. go-plus.json negative regulation of translation in response to sucrose http://purl.obolibrary.org/obo/GO_0080149 GO:0080142 biolink:BiologicalProcess regulation of salicylic acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0080142 GO:0080143 biolink:BiologicalProcess regulation of amino acid export Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0080143 GO:0080144 biolink:BiologicalProcess amino acid homeostasis Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0080144 GO:0080145 biolink:BiologicalProcess cysteine homeostasis Any process involved in the maintenance of an internal steady state of cysteine within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0080145 GO:0080140 biolink:BiologicalProcess regulation of jasmonic acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0080140 GO:0080141 biolink:BiologicalProcess regulation of jasmonic acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0080141 UBERON:0003240 biolink:AnatomicalEntity epithelium of lateral semicircular canal An epithelium that is part of a lateral semicircular canal [Automatically generated definition]. go-plus.json epithelial tissue of lateral semicircular canal|lateral semicircular canal epithelial tissue|lateral semicircular canal epithelium http://purl.obolibrary.org/obo/UBERON_0003240 UBERON:0003249 biolink:AnatomicalEntity epithelium of otic placode An epithelium that is part of a otic placode [Automatically generated definition]. go-plus.json otic epithelium|epithelial tissue of otic placode|otic placode epithelial tissue|otic placode epithelium http://purl.obolibrary.org/obo/UBERON_0003249 UBERON:0003247 biolink:AnatomicalEntity epithelium of forearm An epithelium that is part of a lower arm [Automatically generated definition]. go-plus.json forearm epithelium http://purl.obolibrary.org/obo/UBERON_0003247 UBERON:0003248 biolink:AnatomicalEntity epithelium of footplate An epithelium that is part of a footplate. go-plus.json foot plate epithelium|footplate epithelium http://purl.obolibrary.org/obo/UBERON_0003248 UBERON:0003244 biolink:AnatomicalEntity epithelium of mammary gland the epithelial layer of the luminal surfaces of the mammary gland go-plus.json mammary gland epithelial tissue|mammary gland epithelium|epithelium of lactiferous gland|lactiferous gland epithelium|mammary epithelium http://purl.obolibrary.org/obo/UBERON_0003244 CHEBI:46850 biolink:ChemicalSubstance organoammonium salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_46850 CHEBI:46851 biolink:ChemicalSubstance N-(2-hydroxyethyl)piperazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46851 CHEBI:22881 biolink:ChemicalSubstance biopterins go-plus.json http://purl.obolibrary.org/obo/CHEBI_22881 CHEBI:46853 biolink:ChemicalSubstance piperazinecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46853 CHEBI:46854 biolink:ChemicalSubstance L-glutamo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_46854 UBERON:0003229 biolink:AnatomicalEntity epithelium of elbow An epithelium that is part of a elbow [Automatically generated definition]. go-plus.json cubital region epithelial tissue|epithelial tissue of elbow|elbow epithelial tissue|elbow epithelium|epithelial tissue of cubital region|epithelium of cubital region|cubital region epithelium http://purl.obolibrary.org/obo/UBERON_0003229 CHEBI:46855 biolink:ChemicalSubstance L-alpha-glutamyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_46855 CHEBI:46856 biolink:ChemicalSubstance 11-cis-retinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46856 GO:0080179 biolink:BiologicalProcess 1-methylguanosine metabolic process The chemical reactions and pathways involving 1-methylguanosine. go-plus.json http://purl.obolibrary.org/obo/GO_0080179 CHEBI:32205 biolink:ChemicalSubstance tetracenomycin F1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_32205 CHEBI:32207 biolink:ChemicalSubstance tetracenomycin F2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_32207 GO:0080175 biolink:BiologicalProcess phragmoplast microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells. go-plus.json phragmoplast microtubule organisation|phragmoplast microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0080175 GO:0080176 biolink:MolecularActivity xyloglucan 1,6-alpha-xylosidase activity Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus. go-plus.json http://purl.obolibrary.org/obo/GO_0080176 GO:0080177 biolink:BiologicalProcess plastoglobule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids. go-plus.json plastoglobule organisation http://purl.obolibrary.org/obo/GO_0080177 GO:0080178 biolink:BiologicalProcess 5-carbamoylmethyl uridine residue modification The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA. go-plus.json 5-carbamoylmethyluridine metabolic process http://purl.obolibrary.org/obo/GO_0080178 GO:0080171 biolink:BiologicalProcess lytic vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole. go-plus.json lytic vacuolar assembly|lytic vacuole organization and biogenesis|lytic vacuole biogenesis|lytic vacuole organisation http://purl.obolibrary.org/obo/GO_0080171 UBERON:0003230 biolink:AnatomicalEntity epithelium of carpal region An epithelium that is part of a wrist [Automatically generated definition]. go-plus.json epithelium of wrist|epithelial tissue of wrist|carpal region epithelium|epithelial tissue of carpal region|wrist epithelial tissue|wrist epithelium|carpal region epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003230 UBERON:0003231 biolink:AnatomicalEntity epithelium of hip An epithelium that is part of a hip [Automatically generated definition]. go-plus.json hip region epithelium|regio coxae epithelium|epithelial tissue of hip|epithelium of regio coxae|hip epithelial tissue|hip epithelium|epithelial tissue of hip region|epithelial tissue of regio coxae|epithelium of hip region|regio coxae epithelial tissue|hip region epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003231 GO:0080172 biolink:BiologicalProcess petal epidermis patterning The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0080172 GO:0080173 biolink:BiologicalProcess male-female gamete recognition during double fertilization forming a zygote and endosperm The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana. go-plus.json gamete recognition|male-female gamete recognition http://purl.obolibrary.org/obo/GO_0080173 GO:0080174 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0080174 CHEBI:32202 biolink:ChemicalSubstance tetracenomycin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_32202 GO:0080170 biolink:BiologicalProcess hydrogen peroxide transmembrane transport The process in which hydrogen peroxide is transported across a membrane. go-plus.json hydrogen peroxide membrane transport http://purl.obolibrary.org/obo/GO_0080170 UBERON:0003238 biolink:AnatomicalEntity epithelium of superior semicircular canal An epithelium that is part of an anterior semicircular canal [Automatically generated definition]. go-plus.json epithelial tissue of superior semicircular canal|superior semicircular canal epithelial tissue|epithelium of anterior semicircular canal|epithelial tissue of anterior semicircular canal|anterior semicircular canal epithelial tissue|anterior semicircular canal epithelium|superior semicircular canal epithelium http://purl.obolibrary.org/obo/UBERON_0003238 UBERON:0003239 biolink:AnatomicalEntity epithelium of posterior semicircular canal An epithelium that is part of a posterior semicircular canal [Automatically generated definition]. go-plus.json posterior semicircular canal epithelium|epithelial tissue of posterior semicircular canal|posterior semicircular canal epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003239 CHEBI:46858 biolink:ChemicalSubstance L-tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_46858 chebi_ph7_3 UBERON:0003236 biolink:AnatomicalEntity epithelium of lower jaw An epithelium that is part of a lower jaw [Automatically generated definition]. go-plus.json epithelium of ventral mandibular arch|epithelial tissue of ventral mandibular arch|ventral mandibular arch epithelial tissue|ventral mandibular arch epithelium|epithelial tissue of lower jaw|lower jaw epithelial tissue|lower jaw epithelium http://purl.obolibrary.org/obo/UBERON_0003236 CHEBI:22888 biolink:ChemicalSubstance biphenyls go-plus.json http://purl.obolibrary.org/obo/CHEBI_22888 UBERON:0003235 biolink:AnatomicalEntity epithelium of upper jaw An epithelium that is part of a upper jaw [Automatically generated definition]. go-plus.json epithelium of palatoquadrate arch|epithelial tissue of palatoquadrate arch|palatoquadrate arch epithelium|palatoquadrate arch epithelial tissue|epithelial tissue of upper jaw|upper jaw epithelial tissue|upper jaw epithelium http://purl.obolibrary.org/obo/UBERON_0003235 UBERON:0003232 biolink:AnatomicalEntity epithelium of knee An epithelium that is part of a knee [Automatically generated definition]. go-plus.json epithelial tissue of knee|knee epithelial tissue|knee epithelium http://purl.obolibrary.org/obo/UBERON_0003232 UBERON:0003233 biolink:AnatomicalEntity epithelium of shoulder An epithelium that is part of a shoulder [Automatically generated definition]. go-plus.json epithelial tissue of shoulder|shoulder epithelial tissue|shoulder epithelium http://purl.obolibrary.org/obo/UBERON_0003233 CHEBI:22894 biolink:ChemicalSubstance bis(molybdopterin guanine dinucleotide)molybdenum go-plus.json http://purl.obolibrary.org/obo/CHEBI_22894 CHEBI:46842 biolink:ChemicalSubstance sarcosinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_46842 UBERON:0003218 biolink:AnatomicalEntity ovary septum Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003218 CHEBI:46845 biolink:ChemicalSubstance N-alkylpiperazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46845 GO:0080168 biolink:BiologicalProcess abscisic acid transport The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0080168 GO:0080169 biolink:BiologicalProcess cellular response to boron-containing substance deprivation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances. go-plus.json cellular response to boron deprivation|cellular response to boron starvation http://purl.obolibrary.org/obo/GO_0080169 GO:0080164 biolink:BiologicalProcess regulation of nitric oxide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. go-plus.json http://purl.obolibrary.org/obo/GO_0080164 GO:0080165 biolink:BiologicalProcess callose deposition in phloem sieve plate Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. go-plus.json http://purl.obolibrary.org/obo/GO_0080165 GO:0080166 biolink:BiologicalProcess stomium development The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released. go-plus.json http://purl.obolibrary.org/obo/GO_0080166 GO:0080167 biolink:BiologicalProcess response to karrikin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants). go-plus.json http://purl.obolibrary.org/obo/GO_0080167 GO:0080160 biolink:BiologicalProcess selenate transport The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0080160 GO:0080161 biolink:MolecularActivity auxin transmembrane transporter activity Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth. go-plus.json http://purl.obolibrary.org/obo/GO_0080161 UBERON:0003220 biolink:AnatomicalEntity metanephric mesenchyme one of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO] go-plus.json metanephrogenic mesenchyme|metanephric blastema|metanephros associated mesenchyme|metanephric mesoderm http://purl.obolibrary.org/obo/UBERON_0003220 GO:0080162 biolink:BiologicalProcess intracellular auxin transport The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth. go-plus.json http://purl.obolibrary.org/obo/GO_0080162 GO:0080163 biolink:BiologicalProcess regulation of protein serine/threonine phosphatase activity Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. go-plus.json regulation of protein phosphatase type 2c activity http://purl.obolibrary.org/obo/GO_0080163 CHEBI:46846 biolink:ChemicalSubstance piperazinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_46846 CHEBI:46847 biolink:ChemicalSubstance N-iminopiperazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46847 CHEBI:46848 biolink:ChemicalSubstance N-arylpiperazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46848 CHEBI:22899 biolink:ChemicalSubstance bisdechlorogeodin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22899 chebi_ph7_3 UBERON:0003221 biolink:AnatomicalEntity phalanx Endochondral bones that are often elongate and arranged in rows of articulating elements, and form the visible part of the digits. go-plus.json digit long bone|phalange|phalanges|long bone of digit|phalanx bone http://purl.obolibrary.org/obo/UBERON_0003221 GO:0031348 biolink:BiologicalProcess negative regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. go-plus.json down-regulation of defense response|downregulation of defense response|down regulation of defense response|inhibition of defense response http://purl.obolibrary.org/obo/GO_0031348 GO:0031349 biolink:BiologicalProcess positive regulation of defense response Any process that activates or increases the frequency, rate or extent of a defense response. go-plus.json stimulation of defense response|up-regulation of defense response|activation of defense response|up regulation of defense response|upregulation of defense response http://purl.obolibrary.org/obo/GO_0031349 GO:0031346 biolink:BiologicalProcess positive regulation of cell projection organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. go-plus.json positive regulation of cell projection organisation|positive regulation of cell projection organization and biogenesis|up regulation of cell projection organization|upregulation of cell projection organization|stimulation of cell projection organization|up-regulation of cell projection organization|activation of cell projection organization http://purl.obolibrary.org/obo/GO_0031346 GO:0031347 biolink:BiologicalProcess regulation of defense response Any process that modulates the frequency, rate or extent of a defense response. go-plus.json http://purl.obolibrary.org/obo/GO_0031347 GO:0045996 biolink:BiologicalProcess negative regulation of transcription by pheromones Any process involving pheromones that stops, prevents or reduces the rate of transcription. go-plus.json inhibition of transcription by pheromones|down regulation of transcription by pheromones|downregulation of transcription by pheromones|down-regulation of transcription by pheromones http://purl.obolibrary.org/obo/GO_0045996 GO:0006388 biolink:BiologicalProcess tRNA splicing, via endonucleolytic cleavage and ligation Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. go-plus.json tRNA-Y splicing http://purl.obolibrary.org/obo/GO_0006388 GO:0006389 biolink:BiologicalProcess obsolete tRNA-Y splicing OBSOLETE. (Was not defined before being made obsolete). go-plus.json tRNA-Y splicing http://purl.obolibrary.org/obo/GO_0006389 GO:0045997 biolink:BiologicalProcess negative regulation of ecdysteroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. go-plus.json negative regulation of ecdysteroid anabolism|down-regulation of ecdysteroid biosynthetic process|negative regulation of ecdysteroid biosynthesis|negative regulation of ecdysteroid synthesis|negative regulation of ecdysteroid formation|downregulation of ecdysteroid biosynthetic process|down regulation of ecdysteroid biosynthetic process|inhibition of ecdysteroid biosynthetic process http://purl.obolibrary.org/obo/GO_0045997 GO:0006386 biolink:BiologicalProcess termination of RNA polymerase III transcription The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues. go-plus.json transcription termination from RNA polymerase III promoter|RNA polymerase III transcription termination factor activity|transcription termination from Pol III promoter|RNA polymerase III transcription termination http://purl.obolibrary.org/obo/GO_0006386 GO:0045994 biolink:BiologicalProcess positive regulation of translational initiation by iron Any process involving iron that activates or increases the rate of translational initiation. go-plus.json upregulation of translational initiation by iron|stimulation of translational initiation by iron|activation of translational initiation by iron|up-regulation of translational initiation by iron|up regulation of translational initiation by iron http://purl.obolibrary.org/obo/GO_0045994 GO:0045995 biolink:BiologicalProcess regulation of embryonic development Any process that modulates the frequency, rate or extent of embryonic development. go-plus.json http://purl.obolibrary.org/obo/GO_0045995 GO:0006387 biolink:BiologicalProcess obsolete snRNA capping OBSOLETE. The sequence of enzymatic reactions resulting in the addition of a cap to the 5' end of a nascent snRNA transcript. go-plus.json snRNA capping http://purl.obolibrary.org/obo/GO_0006387 GO:0006384 biolink:BiologicalProcess transcription initiation from RNA polymerase III promoter Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. go-plus.json transcription initiation from Pol III promoter|transcription initiation from RNA polymerase III type 1 promoter|transcription initiation from RNA polymerase III type 2 promoter|transcription initiation from RNA polymerase III type 3 promoter|transcription initiation from RNA polymerase III hybrid type promoter http://purl.obolibrary.org/obo/GO_0006384 GO:0045992 biolink:BiologicalProcess negative regulation of embryonic development Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. go-plus.json down regulation of embryonic development|downregulation of embryonic development|down-regulation of embryonic development|inhibition of embryonic development http://purl.obolibrary.org/obo/GO_0045992 GO:0045993 biolink:BiologicalProcess negative regulation of translational initiation by iron Any process involving iron that stops, prevents or reduces the rate of translational initiation. go-plus.json down regulation of translational initiation by iron|inhibition of translational initiation by iron|down-regulation of translational initiation by iron|downregulation of translational initiation by iron http://purl.obolibrary.org/obo/GO_0045993 GO:0006385 biolink:BiologicalProcess transcription elongation from RNA polymerase III promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III. go-plus.json RNA polymerase III transcription elongation factor activity|RNA elongation from Pol III promoter http://purl.obolibrary.org/obo/GO_0006385 GO:0006382 biolink:BiologicalProcess adenosine to inosine editing The conversion of an adenosine residue to inosine in an RNA molecule by deamination. go-plus.json http://purl.obolibrary.org/obo/GO_0006382 GO:0045990 biolink:BiologicalProcess carbon catabolite regulation of transcription A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. go-plus.json regulation of transcription by carbon catabolites http://purl.obolibrary.org/obo/GO_0045990 GO:0006383 biolink:BiologicalProcess transcription by RNA polymerase III The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter. go-plus.json transcription from RNA polymerase III type 3 promoter|RNA polymerase III transcription factor activity|transcription from a RNA polymerase III hybrid type promoter|U2 snRNA transcription (S. cerevisiae)|transcription from Pol III promoter|transcription from RNA polymerase III promoter|U6 snRNA transcription (mammalian)|transcription from RNA polymerase III type 2 promoter http://purl.obolibrary.org/obo/GO_0006383 goslim_yeast GO:0045991 biolink:BiologicalProcess carbon catabolite activation of transcription A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. go-plus.json positive regulation of transcription by carbon catabolites http://purl.obolibrary.org/obo/GO_0045991 GO:0006391 biolink:BiologicalProcess transcription initiation from mitochondrial promoter A transcription initiation process that takes place at a promoter on the mitochondrial chromosome, and results in RNA synthesis by a mitochondrial RNA polymerase. go-plus.json http://purl.obolibrary.org/obo/GO_0006391 GO:0006392 biolink:BiologicalProcess transcription elongation from mitochondrial promoter The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase. go-plus.json RNA elongation from mitochondrial promoter http://purl.obolibrary.org/obo/GO_0006392 GO:0070958 biolink:BiologicalProcess negative regulation of neutrophil mediated killing of gram-positive bacterium Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil. go-plus.json down regulation of neutrophil mediated killing of gram-positive bacterium|inhibition of neutrophil mediated killing of gram-positive bacterium|down-regulation of neutrophil mediated killing of gram-positive bacterium|downregulation of neutrophil mediated killing of gram-positive bacterium http://purl.obolibrary.org/obo/GO_0070958 GO:0070959 biolink:BiologicalProcess negative regulation of neutrophil mediated killing of fungus Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil. go-plus.json down-regulation of neutrophil mediated killing of fungus|inhibition of neutrophil mediated killing of fungus|down regulation of neutrophil mediated killing of fungus|downregulation of neutrophil mediated killing of fungus http://purl.obolibrary.org/obo/GO_0070959 GO:0006390 biolink:BiologicalProcess mitochondrial transcription The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase. go-plus.json transcription from mitochondrial promoter http://purl.obolibrary.org/obo/GO_0006390 GO:0070956 biolink:BiologicalProcess negative regulation of neutrophil mediated killing of bacterium Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil. go-plus.json down-regulation of neutrophil mediated killing of bacterium|downregulation of neutrophil mediated killing of bacterium|down regulation of neutrophil mediated killing of bacterium|inhibition of neutrophil mediated killing of bacterium http://purl.obolibrary.org/obo/GO_0070956 GO:0070957 biolink:BiologicalProcess negative regulation of neutrophil mediated killing of gram-negative bacterium Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil. go-plus.json downregulation of neutrophil mediated killing of gram-negative bacterium|down regulation of neutrophil mediated killing of gram-negative bacterium|inhibition of neutrophil mediated killing of gram-negative bacterium|down-regulation of neutrophil mediated killing of gram-negative bacterium http://purl.obolibrary.org/obo/GO_0070957 GO:0045998 biolink:BiologicalProcess positive regulation of ecdysteroid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. go-plus.json activation of ecdysteroid biosynthetic process|up-regulation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid anabolism|positive regulation of ecdysteroid synthesis|positive regulation of ecdysteroid formation|positive regulation of ecdysteroid biosynthesis|up regulation of ecdysteroid biosynthetic process|upregulation of ecdysteroid biosynthetic process|stimulation of ecdysteroid biosynthetic process http://purl.obolibrary.org/obo/GO_0045998 GO:0070954 biolink:BiologicalProcess negative regulation of neutrophil mediated cytotoxicity Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. go-plus.json down-regulation of neutrophil mediated cytotoxicity|downregulation of neutrophil mediated cytotoxicity|down regulation of neutrophil mediated cytotoxicity|inhibition of neutrophil mediated cytotoxicity|negative regulation of neutrophil mediated cell killing http://purl.obolibrary.org/obo/GO_0070954 GO:0045999 biolink:BiologicalProcess negative regulation of ecdysteroid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid. go-plus.json down-regulation of ecdysteroid secretion|inhibition of ecdysteroid secretion|down regulation of ecdysteroid secretion|downregulation of ecdysteroid secretion http://purl.obolibrary.org/obo/GO_0045999 GO:0070955 biolink:BiologicalProcess negative regulation of neutrophil mediated killing of symbiont cell Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil. go-plus.json down-regulation of neutrophil mediated killing of symbiont cell|downregulation of neutrophil mediated killing of symbiont cell|down regulation of neutrophil mediated killing of symbiont cell|inhibition of neutrophil mediated killing of symbiont cell http://purl.obolibrary.org/obo/GO_0070955 GO:0031344 biolink:BiologicalProcess regulation of cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. go-plus.json regulation of cell projection organization and biogenesis|regulation of cell projection organisation http://purl.obolibrary.org/obo/GO_0031344 GO:0070952 biolink:BiologicalProcess regulation of neutrophil mediated killing of gram-positive bacterium Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil. go-plus.json http://purl.obolibrary.org/obo/GO_0070952 GO:0070953 biolink:BiologicalProcess regulation of neutrophil mediated killing of fungus Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil. go-plus.json http://purl.obolibrary.org/obo/GO_0070953 GO:0031345 biolink:BiologicalProcess negative regulation of cell projection organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. go-plus.json down-regulation of cell projection organization|negative regulation of cell projection organization and biogenesis|downregulation of cell projection organization|inhibition of cell projection organization|down regulation of cell projection organization|negative regulation of cell projection organisation http://purl.obolibrary.org/obo/GO_0031345 GO:0070950 biolink:BiologicalProcess regulation of neutrophil mediated killing of bacterium Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil. go-plus.json http://purl.obolibrary.org/obo/GO_0070950 GO:0031342 biolink:BiologicalProcess negative regulation of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. go-plus.json down-regulation of cell killing|downregulation of cell killing|down regulation of cell killing|inhibition of cell killing http://purl.obolibrary.org/obo/GO_0031342 GO:0070951 biolink:BiologicalProcess regulation of neutrophil mediated killing of gram-negative bacterium Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil. go-plus.json http://purl.obolibrary.org/obo/GO_0070951 GO:0031343 biolink:BiologicalProcess positive regulation of cell killing Any process that activates or increases the frequency, rate or extent of cell killing. go-plus.json up regulation of cell killing|upregulation of cell killing|stimulation of cell killing|activation of cell killing|up-regulation of cell killing http://purl.obolibrary.org/obo/GO_0031343 GO:0031340 biolink:BiologicalProcess positive regulation of vesicle fusion Any process that activates or increases the frequency, rate or extent of vesicle fusion. go-plus.json up regulation of vesicle fusion|upregulation of vesicle fusion|stimulation of vesicle fusion|up-regulation of vesicle fusion|activation of vesicle fusion http://purl.obolibrary.org/obo/GO_0031340 GO:0031341 biolink:BiologicalProcess regulation of cell killing Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0031341 GO:0031339 biolink:BiologicalProcess negative regulation of vesicle fusion Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. go-plus.json inhibition of vesicle fusion|down-regulation of vesicle fusion|downregulation of vesicle fusion|down regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0031339 GO:0031337 biolink:BiologicalProcess positive regulation of sulfur amino acid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids. go-plus.json upregulation of sulfur amino acid metabolic process|up regulation of sulfur amino acid metabolic process|activation of sulfur amino acid metabolic process|stimulation of sulfur amino acid metabolic process|up-regulation of sulfur amino acid metabolic process|positive regulation of sulfur amino acid metabolism http://purl.obolibrary.org/obo/GO_0031337 GO:0031338 biolink:BiologicalProcess regulation of vesicle fusion Any process that modulates the frequency, rate or extent of vesicle fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0031338 GO:0031335 biolink:BiologicalProcess regulation of sulfur amino acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids. go-plus.json regulation of sulfur amino acid metabolism http://purl.obolibrary.org/obo/GO_0031335 GO:0031336 biolink:BiologicalProcess negative regulation of sulfur amino acid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids. go-plus.json down regulation of sulfur amino acid metabolic process|downregulation of sulfur amino acid metabolic process|down-regulation of sulfur amino acid metabolic process|inhibition of sulfur amino acid metabolic process|negative regulation of sulfur amino acid metabolism http://purl.obolibrary.org/obo/GO_0031336 GO:0006399 biolink:BiologicalProcess tRNA metabolic process The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. go-plus.json tRNA metabolism http://purl.obolibrary.org/obo/GO_0006399 goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl GO:0006397 biolink:BiologicalProcess mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. go-plus.json mRNA maturation http://purl.obolibrary.org/obo/GO_0006397 goslim_generic|goslim_chembl|goslim_yeast GO:0006398 biolink:BiologicalProcess mRNA 3'-end processing by stem-loop binding and cleavage Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine. go-plus.json histone mRNA 3' end processing http://purl.obolibrary.org/obo/GO_0006398 GO:0006395 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006395 GO:0006396 biolink:BiologicalProcess RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. Wikipedia:Post-transcriptional_modification go-plus.json http://purl.obolibrary.org/obo/GO_0006396 goslim_pir GO:0006393 biolink:BiologicalProcess termination of mitochondrial transcription The process in which the synthesis of an RNA molecule using a mitochondrial DNA template is completed. go-plus.json mitochondrial transcription termination|RNA transcription termination from mitochondrial promoter http://purl.obolibrary.org/obo/GO_0006393 GO:0006394 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006394 GO:0070949 biolink:BiologicalProcess regulation of neutrophil mediated killing of symbiont cell Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil. go-plus.json http://purl.obolibrary.org/obo/GO_0070949 GO:0070947 biolink:BiologicalProcess neutrophil-mediated killing of fungus The directed killing of a fungal cell by a neutrophil. go-plus.json neutrophil mediated killing of fungus http://purl.obolibrary.org/obo/GO_0070947 GO:0070948 biolink:BiologicalProcess regulation of neutrophil mediated cytotoxicity Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil. go-plus.json regulation of neutrophil mediated cell killing http://purl.obolibrary.org/obo/GO_0070948 GO:0070945 biolink:BiologicalProcess neutrophil-mediated killing of gram-negative bacterium The directed killing of a gram-negative bacterium by a neutrophil. go-plus.json neutrophil mediated killing of gram-negative bacterium http://purl.obolibrary.org/obo/GO_0070945 GO:0070946 biolink:BiologicalProcess neutrophil-mediated killing of gram-positive bacterium The directed killing of a gram-positive bacterium by a neutrophil. go-plus.json neutrophil mediated killing of gram-positive bacterium http://purl.obolibrary.org/obo/GO_0070946 GO:0070943 biolink:BiologicalProcess neutrophil-mediated killing of symbiont cell The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json neutrophil mediated killing of symbiont cell http://purl.obolibrary.org/obo/GO_0070943 GO:0070944 biolink:BiologicalProcess neutrophil-mediated killing of bacterium The directed killing of a bacterium by a neutrophil. go-plus.json neutrophil mediated killing of bacterium http://purl.obolibrary.org/obo/GO_0070944 GO:0031333 biolink:BiologicalProcess negative regulation of protein-containing complex assembly Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. go-plus.json down-regulation of protein complex assembly|negative regulation of protein complex assembly|downregulation of protein complex assembly|down regulation of protein complex assembly|inhibition of protein complex assembly http://purl.obolibrary.org/obo/GO_0031333 GO:0070941 biolink:BiologicalProcess eisosome assembly The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0070941 GO:0031334 biolink:BiologicalProcess positive regulation of protein-containing complex assembly Any process that activates or increases the frequency, rate or extent of protein complex assembly. go-plus.json stimulation of protein complex assembly|up-regulation of protein complex assembly|activation of protein complex assembly|up regulation of protein complex assembly|positive regulation of protein complex assembly|upregulation of protein complex assembly http://purl.obolibrary.org/obo/GO_0031334 GO:0070942 biolink:BiologicalProcess neutrophil mediated cytotoxicity The directed killing of a target cell by a neutrophil. go-plus.json neutrophil mediated cell killing http://purl.obolibrary.org/obo/GO_0070942 GO:0031331 biolink:BiologicalProcess positive regulation of cellular catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. go-plus.json upregulation of cellular catabolic process|stimulation of cellular catabolic process|up-regulation of cellular catabolic process|activation of cellular catabolic process|positive regulation of cellular catabolism|positive regulation of cellular degradation|positive regulation of cellular breakdown|up regulation of cellular catabolic process http://purl.obolibrary.org/obo/GO_0031331 GO:0070940 biolink:BiologicalProcess dephosphorylation of RNA polymerase II C-terminal domain The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form. go-plus.json CTD domain dephosphorylation of RNA polymerase II|generation of II(A) form of RNA polymerase II|generation of hypophosphorylated CTD of RNA polymerase II http://purl.obolibrary.org/obo/GO_0070940 GO:0031332 biolink:CellularComponent RNAi effector complex Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0031332 goslim_pir GO:0031330 biolink:BiologicalProcess negative regulation of cellular catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. go-plus.json down regulation of cellular catabolic process|inhibition of cellular catabolic process|negative regulation of cellular degradation|negative regulation of cellular breakdown|negative regulation of cellular catabolism|down-regulation of cellular catabolic process|downregulation of cellular catabolic process http://purl.obolibrary.org/obo/GO_0031330 GO:0031328 biolink:BiologicalProcess positive regulation of cellular biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. go-plus.json up regulation of cellular biosynthetic process|activation of cellular biosynthetic process|positive regulation of cellular biosynthesis|stimulation of cellular biosynthetic process|up-regulation of cellular biosynthetic process|positive regulation of cellular anabolism|positive regulation of cellular synthesis|positive regulation of cellular formation|upregulation of cellular biosynthetic process http://purl.obolibrary.org/obo/GO_0031328 GO:0031329 biolink:BiologicalProcess regulation of cellular catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. go-plus.json regulation of cellular degradation|regulation of cellular breakdown|regulation of cellular catabolism http://purl.obolibrary.org/obo/GO_0031329 GO:0031326 biolink:BiologicalProcess regulation of cellular biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. go-plus.json regulation of cellular anabolism|regulation of cellular synthesis|regulation of cellular biosynthesis|regulation of cellular formation http://purl.obolibrary.org/obo/GO_0031326 GO:0031327 biolink:BiologicalProcess negative regulation of cellular biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. go-plus.json downregulation of cellular biosynthetic process|down-regulation of cellular biosynthetic process|negative regulation of cellular biosynthesis|negative regulation of cellular anabolism|inhibition of cellular biosynthetic process|negative regulation of cellular synthesis|negative regulation of cellular formation|down regulation of cellular biosynthetic process http://purl.obolibrary.org/obo/GO_0031327 GO:0031324 biolink:BiologicalProcess negative regulation of cellular metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. go-plus.json down-regulation of cellular metabolic process|downregulation of cellular metabolic process|negative regulation of cellular metabolism|down regulation of cellular metabolic process|inhibition of cellular metabolic process http://purl.obolibrary.org/obo/GO_0031324 GO:0006368 biolink:BiologicalProcess transcription elongation from RNA polymerase II promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II. go-plus.json RNA polymerase II transcription elongation factor activity|RNA elongation from Pol II promoter http://purl.obolibrary.org/obo/GO_0006368 GO:0006369 biolink:BiologicalProcess termination of RNA polymerase II transcription The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed. go-plus.json transcription termination from RNA polymerase II promoter|RNA polymerase II transcription termination|transcription termination from Pol II promoter|RNA polymerase II transcription termination factor activity|RNA 3'-end formation by RNA polymerase II http://purl.obolibrary.org/obo/GO_0006369 GO:0031325 biolink:BiologicalProcess positive regulation of cellular metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. go-plus.json up regulation of cellular metabolic process|positive regulation of cellular metabolism|upregulation of cellular metabolic process|stimulation of cellular metabolic process|up-regulation of cellular metabolic process|activation of cellular metabolic process http://purl.obolibrary.org/obo/GO_0031325 GO:0006366 biolink:BiologicalProcess transcription by RNA polymerase II The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). go-plus.json gene-specific transcription from RNA polymerase II promoter|general transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from Pol II promoter|RNA polymerase II transcription factor activity|specific transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0006366 goslim_yeast GO:0006367 biolink:BiologicalProcess transcription initiation from RNA polymerase II promoter Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. go-plus.json transcription initiation from Pol II promoter http://purl.obolibrary.org/obo/GO_0006367 GO:0006364 biolink:BiologicalProcess rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. go-plus.json 35S primary transcript processing http://purl.obolibrary.org/obo/GO_0006364 goslim_yeast GO:0006365 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006365 GO:0006362 biolink:BiologicalProcess transcription elongation from RNA polymerase I promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I. go-plus.json RNA polymerase I transcription elongation factor activity|RNA elongation from Pol I promoter http://purl.obolibrary.org/obo/GO_0006362 GO:0006363 biolink:BiologicalProcess termination of RNA polymerase I transcription The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit. go-plus.json RNA polymerase I transcription termination|transcription termination from RNA polymerase I promoter|RNA polymerase I transcription termination factor activity|transcription termination from Pol I promoter|termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript http://purl.obolibrary.org/obo/GO_0006363 CHEBI:165870 biolink:ChemicalSubstance N-6-Trimethyllysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_165870 GO:0006360 biolink:BiologicalProcess transcription by RNA polymerase I The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter. go-plus.json RNA polymerase I transcription factor activity|transcription from Pol I promoter|transcription from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0006360 goslim_yeast GO:0006361 biolink:BiologicalProcess transcription initiation from RNA polymerase I promoter Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. go-plus.json transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript|transcription initiation from Pol I promoter http://purl.obolibrary.org/obo/GO_0006361 GO:0006370 biolink:BiologicalProcess 7-methylguanosine mRNA capping Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. go-plus.json 5' mRNA capping|5'-end processing|5' end capping|5'-end mRNA processing|mRNA capping http://purl.obolibrary.org/obo/GO_0006370 GO:0070978 biolink:BiologicalProcess voltage-gated calcium channel complex assembly Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070978 GO:0070979 biolink:BiologicalProcess protein K11-linked ubiquitination A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains. go-plus.json http://purl.obolibrary.org/obo/GO_0070979 GO:0070976 biolink:MolecularActivity TIR domain binding Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. go-plus.json Toll-Interleukin receptor domain binding http://purl.obolibrary.org/obo/GO_0070976 goslim_chembl GO:0070977 biolink:BiologicalProcess bone maturation A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0070977 GO:0031322 biolink:BiologicalProcess ascospore-type prospore-specific spindle pole body remodeling A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP). go-plus.json sporulation-specific spindle pole body remodeling|prospore-specific spindle pole body remodeling|forespore specific spindle pole body remodeling|ascospore-type prospore-specific spindle pole body modification|ascospore-type prospore-specific spindle pole body remodelling|forespore-specific spindle pole body remodeling http://purl.obolibrary.org/obo/GO_0031322 GO:0070974 biolink:MolecularActivity POU domain binding Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors. go-plus.json http://purl.obolibrary.org/obo/GO_0070974 GO:0031323 biolink:BiologicalProcess regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. go-plus.json regulation of cellular metabolism http://purl.obolibrary.org/obo/GO_0031323 GO:0070975 biolink:MolecularActivity FHA domain binding Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich. go-plus.json Forkhead-associated domain binding http://purl.obolibrary.org/obo/GO_0070975 GO:0070972 biolink:BiologicalProcess protein localization to endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum. go-plus.json protein localization in endoplasmic reticulum|protein localization in ER|protein localisation in endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0070972 GO:0031320 biolink:MolecularActivity hexitol dehydrogenase activity Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0031320 GO:0070973 biolink:BiologicalProcess protein localization to endoplasmic reticulum exit site A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site. go-plus.json protein localization to ER exit site|protein localisation to endoplasmic reticulum exit site http://purl.obolibrary.org/obo/GO_0070973 GO:0031321 biolink:BiologicalProcess ascospore-type prospore assembly During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane. go-plus.json ascospore-type prospore formation|forespore formation http://purl.obolibrary.org/obo/GO_0031321 GO:0070970 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070970 GO:0070971 biolink:CellularComponent endoplasmic reticulum exit site An endoplasmic reticulum part at which COPII-coated vesicles are produced. NIF_Subcellular:sao124393998 go-plus.json transitional ER|ER exit site http://purl.obolibrary.org/obo/GO_0070971 GO:0031319 biolink:BiologicalProcess detection of cAMP The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP. go-plus.json detection of 3',5'-cAMP|detection of adenosine 3',5'-cyclophosphate|3',5'-cAMP sensing|cAMP sensing|detection of cyclic AMP|3',5'-cAMP detection|cAMP detection|detection of 3',5' cAMP|cyclic AMP detection http://purl.obolibrary.org/obo/GO_0031319 OBA:0005997 biolink:OntologyClass peroxisome morphology The morphology of a peroxisome. go-plus.json morphology of peroxisome http://purl.obolibrary.org/obo/OBA_0005997 GO:0031317 biolink:CellularComponent tripartite ATP-independent periplasmic transporter complex A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients. go-plus.json TRAP-T transporter complex|TRAP transporter complex http://purl.obolibrary.org/obo/GO_0031317 GO:0021990 biolink:BiologicalProcess neural plate formation The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0021990 GO:0031318 biolink:BiologicalProcess detection of folic acid The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal. go-plus.json detection of folate|folate sensing|folate detection|folic acid sensing|folic acid detection http://purl.obolibrary.org/obo/GO_0031318 GO:0021991 biolink:BiologicalProcess neural plate thickening The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode. go-plus.json http://purl.obolibrary.org/obo/GO_0021991 GO:0021992 biolink:BiologicalProcess cell proliferation involved in neural plate elongation The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0021992 GO:0031315 biolink:CellularComponent extrinsic component of mitochondrial outer membrane The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0031315 GO:0031316 biolink:CellularComponent extrinsic component of nuclear outer membrane The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to nuclear outer membrane http://purl.obolibrary.org/obo/GO_0031316 GO:0021993 biolink:BiologicalProcess initiation of neural tube closure The process in which closure points are established at multiple points and along the neural rostrocaudal axis. go-plus.json http://purl.obolibrary.org/obo/GO_0021993 GO:0006379 biolink:BiologicalProcess mRNA cleavage Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. go-plus.json cleavage stimulation factor activity http://purl.obolibrary.org/obo/GO_0006379 GO:0031313 biolink:CellularComponent extrinsic component of endosome membrane The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to endosome membrane http://purl.obolibrary.org/obo/GO_0031313 GO:0021994 biolink:BiologicalProcess progression of neural tube closure The process in which the neural folds are fused extending from the initial closure points. go-plus.json http://purl.obolibrary.org/obo/GO_0021994 GO:0021995 biolink:BiologicalProcess neuropore closure The process of joining together the neural folds at either end of the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0021995 GO:0031314 biolink:CellularComponent extrinsic component of mitochondrial inner membrane The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to mitochondrial inner membrane http://purl.obolibrary.org/obo/GO_0031314 GO:0006377 biolink:BiologicalProcess obsolete MATa1 (A1) pre-mRNA splicing OBSOLETE. (Was not defined before being made obsolete). go-plus.json MATa1 (A1) pre-mRNA splicing http://purl.obolibrary.org/obo/GO_0006377 GO:0006378 biolink:BiologicalProcess mRNA polyadenylation The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript. go-plus.json mRNA polyadenylylation|cleavage and polyadenylylation specificity factor activity http://purl.obolibrary.org/obo/GO_0006378 GO:0006375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006375 GO:0006376 biolink:BiologicalProcess mRNA splice site selection Selection of a splice site by components of the assembling spliceosome. go-plus.json spliceosomal commitment complex biosynthesis|spliceosomal E complex formation|spliceosomal E complex biosynthesis|spliceosomal commitment complex formation http://purl.obolibrary.org/obo/GO_0006376 GO:0006373 biolink:BiologicalProcess obsolete 3'-splice site cleavage, exon ligation OBSOLETE. (Was not defined before being made obsolete). go-plus.json 3'-splice site cleavage, exon ligation http://purl.obolibrary.org/obo/GO_0006373 GO:0006374 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006374 GO:0006371 biolink:BiologicalProcess obsolete mRNA splicing OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, so that mRNA consisting only of the joined exons is produced. go-plus.json mRNA splicing http://purl.obolibrary.org/obo/GO_0006371 GO:0006372 biolink:BiologicalProcess obsolete lariat formation, 5'-splice site cleavage OBSOLETE. (Was not defined before being made obsolete). go-plus.json lariat formation, 5'-splice site cleavage http://purl.obolibrary.org/obo/GO_0006372 GO:0006380 biolink:BiologicalProcess obsolete poly-A binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json poly-A binding http://purl.obolibrary.org/obo/GO_0006380 GO:0006381 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006381 GO:0070969 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070969 GO:0070967 biolink:MolecularActivity coenzyme F420 binding Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json http://purl.obolibrary.org/obo/GO_0070967 CHEBI:141855 biolink:ChemicalSubstance 5'-end NTP-ribonucleotide(5-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_141855 chebi_ph7_3 GO:0070968 biolink:MolecularActivity pyrroloquinoline quinone binding Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases. go-plus.json PQQ binding http://purl.obolibrary.org/obo/GO_0070968 GO:0070965 biolink:BiologicalProcess positive regulation of neutrophil mediated killing of fungus Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil. go-plus.json up regulation of neutrophil mediated killing of fungus|activation of neutrophil mediated killing of fungus|stimulation of neutrophil mediated killing of fungus|up-regulation of neutrophil mediated killing of fungus|upregulation of neutrophil mediated killing of fungus http://purl.obolibrary.org/obo/GO_0070965 GO:0070966 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, no-go decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation. go-plus.json no-go decay|nuclear-transcribed mRNA breakdown, no-go decay|nuclear-transcribed mRNA degradation, no-go decay|no-go mRNA decay|nuclear-transcribed mRNA catabolism, no-go decay http://purl.obolibrary.org/obo/GO_0070966 GO:0031311 biolink:CellularComponent intrinsic component of contractile vacuolar membrane The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to contractile vacuolar membrane http://purl.obolibrary.org/obo/GO_0031311 GO:0021996 biolink:BiologicalProcess lamina terminalis formation The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore. go-plus.json http://purl.obolibrary.org/obo/GO_0021996 GO:0070963 biolink:BiologicalProcess positive regulation of neutrophil mediated killing of gram-negative bacterium Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil. go-plus.json up regulation of neutrophil mediated killing of gram-negative bacterium|upregulation of neutrophil mediated killing of gram-negative bacterium|stimulation of neutrophil mediated killing of gram-negative bacterium|up-regulation of neutrophil mediated killing of gram-negative bacterium|activation of neutrophil mediated killing of gram-negative bacterium http://purl.obolibrary.org/obo/GO_0070963 GO:0031312 biolink:CellularComponent extrinsic component of organelle membrane The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to organelle membrane http://purl.obolibrary.org/obo/GO_0031312 GO:0070964 biolink:BiologicalProcess positive regulation of neutrophil mediated killing of gram-positive bacterium Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil. go-plus.json up regulation of neutrophil mediated killing of gram-positive bacterium|upregulation of neutrophil mediated killing of gram-positive bacterium|stimulation of neutrophil mediated killing of gram-positive bacterium|up-regulation of neutrophil mediated killing of gram-positive bacterium|activation of neutrophil mediated killing of gram-positive bacterium http://purl.obolibrary.org/obo/GO_0070964 GO:0021997 biolink:BiologicalProcess neural plate axis specification The pattern specification process in which the axes of the nervous system are established. go-plus.json neural plate axis determination http://purl.obolibrary.org/obo/GO_0021997 GO:0070961 biolink:BiologicalProcess positive regulation of neutrophil mediated killing of symbiont cell Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil. go-plus.json upregulation of neutrophil mediated killing of symbiont cell|stimulation of neutrophil mediated killing of symbiont cell|up-regulation of neutrophil mediated killing of symbiont cell|activation of neutrophil mediated killing of symbiont cell|up regulation of neutrophil mediated killing of symbiont cell http://purl.obolibrary.org/obo/GO_0070961 GO:0021998 biolink:BiologicalProcess neural plate mediolateral regionalization The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate. go-plus.json neural plate mediolateral pattern formation http://purl.obolibrary.org/obo/GO_0021998 GO:0031310 biolink:CellularComponent intrinsic component of vacuolar membrane The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to vacuolar membrane http://purl.obolibrary.org/obo/GO_0031310 GO:0070962 biolink:BiologicalProcess positive regulation of neutrophil mediated killing of bacterium Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil. go-plus.json stimulation of neutrophil mediated killing of bacterium|up-regulation of neutrophil mediated killing of bacterium|activation of neutrophil mediated killing of bacterium|up regulation of neutrophil mediated killing of bacterium|upregulation of neutrophil mediated killing of bacterium http://purl.obolibrary.org/obo/GO_0070962 GO:0021999 biolink:BiologicalProcess neural plate anterior/posterior regionalization The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. go-plus.json neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0021999 GO:0070960 biolink:BiologicalProcess positive regulation of neutrophil mediated cytotoxicity Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. go-plus.json up regulation of neutrophil mediated cytotoxicity|upregulation of neutrophil mediated cytotoxicity|positive regulation of neutrophil mediated cell killing|stimulation of neutrophil mediated cytotoxicity|up-regulation of neutrophil mediated cytotoxicity|activation of neutrophil mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0070960 GO:0031308 biolink:CellularComponent intrinsic component of nuclear outer membrane The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to nuclear outer membrane http://purl.obolibrary.org/obo/GO_0031308 GO:0031309 biolink:CellularComponent integral component of nuclear outer membrane The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to nuclear outer membrane http://purl.obolibrary.org/obo/GO_0031309 GO:0031306 biolink:CellularComponent intrinsic component of mitochondrial outer membrane The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0031306 GO:0031307 biolink:CellularComponent integral component of mitochondrial outer membrane The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0031307 GO:0021980 biolink:BiologicalProcess subpallium cell migration The orderly movement of cells from one site to another in the subpallium. go-plus.json http://purl.obolibrary.org/obo/GO_0021980 GO:0006348 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006348 GO:0021981 biolink:BiologicalProcess subpallium radially oriented migration The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. go-plus.json http://purl.obolibrary.org/obo/GO_0021981 GO:0031304 biolink:CellularComponent intrinsic component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to mitochondrial inner membrane http://purl.obolibrary.org/obo/GO_0031304 GO:0021982 biolink:BiologicalProcess pineal gland development The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. go-plus.json epiphysis development http://purl.obolibrary.org/obo/GO_0021982 GO:0031305 biolink:CellularComponent integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to mitochondrial inner membrane http://purl.obolibrary.org/obo/GO_0031305 GO:0006349 biolink:BiologicalProcess regulation of gene expression by genetic imprinting Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself. Wikipedia:Genomic_imprinting go-plus.json regulation of gene expression by DNA imprinting http://purl.obolibrary.org/obo/GO_0006349 SO:0002140 biolink:SequenceFeature early_origin_of_replication An origin of replication that initiates early in S phase. go-plus.json early origin|early origin of replication|early replication origin http://purl.obolibrary.org/obo/SO_0002140 GO:0006346 biolink:BiologicalProcess DNA methylation-dependent heterochromatin assembly Repression of transcription by methylation of DNA, leading to the formation of heterochromatin. go-plus.json methylation-dependent chromatin silencing|methylation-dependent heterochromatic silencing http://purl.obolibrary.org/obo/GO_0006346 GO:0031302 biolink:CellularComponent intrinsic component of endosome membrane The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to endosome membrane http://purl.obolibrary.org/obo/GO_0031302 GO:0021983 biolink:BiologicalProcess pituitary gland development The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. go-plus.json hypophysis development http://purl.obolibrary.org/obo/GO_0021983 GO:0031303 biolink:CellularComponent integral component of endosome membrane The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to endosome membrane http://purl.obolibrary.org/obo/GO_0031303 GO:0006347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006347 SO:0002141 biolink:SequenceFeature late_origin_of_replication An origin of replication that initiates late in S phase. go-plus.json late origin of replication|late origin|late replication origin http://purl.obolibrary.org/obo/SO_0002141 GO:0021984 biolink:BiologicalProcess adenohypophysis development The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. go-plus.json adenophysis development|anterior pituitary development|anterior pituitary gland development http://purl.obolibrary.org/obo/GO_0021984 GO:0006344 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006344 GO:0006345 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006345 GO:0006342 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006342 GO:0006343 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006343 GO:0006340 biolink:BiologicalProcess obsolete negative regulation of transcription of homeotic gene (Polycomb group) OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the Polycomb group. go-plus.json negative regulation of transcription of homeotic gene (Polycomb group) http://purl.obolibrary.org/obo/GO_0006340 GO:0006341 biolink:BiologicalProcess obsolete chromatin insulator sequence binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json chromatin insulator sequence binding http://purl.obolibrary.org/obo/GO_0006341 OBO:GOCHE_37848 biolink:OntologyClass substance with plant hormone role go-plus.json http://purl.obolibrary.org/obo/GOCHE_37848 3_STAR GO:0070998 biolink:BiologicalProcess sensory perception of gravity The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json http://purl.obolibrary.org/obo/GO_0070998 GO:0070999 biolink:BiologicalProcess detection of mechanical stimulus involved in sensory perception of gravity The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0070999 GO:0021985 biolink:BiologicalProcess neurohypophysis development The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. go-plus.json posterior pituitary development|neurophysis development|posterior pituitary gland development http://purl.obolibrary.org/obo/GO_0021985 GO:0070996 biolink:MolecularActivity type 1 melanocortin receptor binding Binding to a type 1 melanocortin receptor. go-plus.json type 1 melanocortin receptor ligand http://purl.obolibrary.org/obo/GO_0070996 GO:0031300 biolink:CellularComponent intrinsic component of organelle membrane The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to organelle membrane http://purl.obolibrary.org/obo/GO_0031300 GO:0021986 biolink:BiologicalProcess habenula development The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland. go-plus.json http://purl.obolibrary.org/obo/GO_0021986 GO:0070997 biolink:BiologicalProcess neuron death The process of cell death in a neuron. go-plus.json neuron cell death|neuronal cell death http://purl.obolibrary.org/obo/GO_0070997 GO:0031301 biolink:CellularComponent integral component of organelle membrane The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to organelle membrane http://purl.obolibrary.org/obo/GO_0031301 GO:0070994 biolink:BiologicalProcess detection of oxidative stress The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0070994 GO:0021987 biolink:BiologicalProcess cerebral cortex development The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. go-plus.json neocortex development|corticogenesis http://purl.obolibrary.org/obo/GO_0021987 GO:0070995 biolink:BiologicalProcess NADPH oxidation A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP. go-plus.json NADP (reduced) dehydrogenation|reduced nicotinamide adenine dinucleotide phosphate dehydrogenation|NADP (reduced) oxidation|reduced nicotinamide adenine dinucleotide phosphate oxidation|NADPH dehydrogenation|reduced NADP dehydrogenation|reduced NADP oxidation http://purl.obolibrary.org/obo/GO_0070995 GO:0021988 biolink:BiologicalProcess olfactory lobe development The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. go-plus.json http://purl.obolibrary.org/obo/GO_0021988 GO:0070992 biolink:CellularComponent translation initiation complex A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site. go-plus.json http://purl.obolibrary.org/obo/GO_0070992 GO:0021989 biolink:BiologicalProcess olfactory cortex development The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. go-plus.json http://purl.obolibrary.org/obo/GO_0021989 GO:0070993 biolink:CellularComponent translation preinitiation complex A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070993 GO:0070990 biolink:MolecularActivity snRNP binding Binding to a small nuclear ribonucleoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0070990 GO:0070991 biolink:MolecularActivity medium-chain-acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12. EC:1.3.99.- go-plus.json MCAD activity http://purl.obolibrary.org/obo/GO_0070991 GO:0006359 biolink:BiologicalProcess regulation of transcription by RNA polymerase III Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III. go-plus.json regulation of transcription from RNA polymerase III promoter|regulation of transcription from Pol III promoter http://purl.obolibrary.org/obo/GO_0006359 GO:0021970 biolink:BiologicalProcess corticospinal neuron axon guidance through the basilar pons The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding through the basilar pons http://purl.obolibrary.org/obo/GO_0021970 GO:0021971 biolink:BiologicalProcess corticospinal neuron axon guidance through the medullary pyramid The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding through the medullary pyramid http://purl.obolibrary.org/obo/GO_0021971 GO:0021972 biolink:BiologicalProcess corticospinal neuron axon guidance through spinal cord The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding through spinal cord http://purl.obolibrary.org/obo/GO_0021972 GO:0006357 biolink:BiologicalProcess regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. go-plus.json global transcription regulation from Pol II promoter|regulation of gene-specific transcription from RNA polymerase II promoter|regulation of transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter|regulation of global transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter, global http://purl.obolibrary.org/obo/GO_0006357 GO:0021973 biolink:BiologicalProcess corticospinal neuron axon decussation The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side. go-plus.json http://purl.obolibrary.org/obo/GO_0021973 GO:0006358 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006358 GO:0006355 biolink:BiologicalProcess regulation of transcription, DNA-templated Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. go-plus.json transcriptional control|regulation of cellular transcription, DNA-dependent|regulation of gene-specific transcription|regulation of transcription, DNA-dependent http://purl.obolibrary.org/obo/GO_0006355 GO:0006356 biolink:BiologicalProcess regulation of transcription by RNA polymerase I Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I. go-plus.json regulation of transcription from Pol I promoter|regulation of transcription from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0006356 GO:0006353 biolink:BiologicalProcess DNA-templated transcription, termination The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. go-plus.json transcription termination factor activity|termination of transcription, DNA-dependent|termination of DNA-dependent transcription|DNA-dependent transcription, termination|transcription termination, DNA-dependent|transcriptional complex disassembly http://purl.obolibrary.org/obo/GO_0006353 goslim_yeast GO:0006354 biolink:BiologicalProcess DNA-templated transcription, elongation The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase. go-plus.json DNA-dependent transcription, elongation|transcription elongation, DNA-dependent|RNA elongation|transcriptional elongation, DNA-dependent http://purl.obolibrary.org/obo/GO_0006354 goslim_yeast|goslim_pir GO:0006351 biolink:BiologicalProcess transcription, DNA-templated The cellular synthesis of RNA on a template of DNA. Wikipedia:Transcription_(genetics) go-plus.json transcription, DNA-dependent|cellular transcription|transcription|DNA-dependent transcription|cellular transcription, DNA-dependent|transcription regulator activity http://purl.obolibrary.org/obo/GO_0006351 goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_pombe GO:0006352 biolink:BiologicalProcess DNA-templated transcription, initiation Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. go-plus.json initiation of transcription, DNA-dependent|transcription initiation factor activity|transcription initiation, DNA-dependent|DNA-dependent RNA polymerase complex assembly at promoter|DNA-dependent transcription, initiation|initiation of DNA-dependent transcription http://purl.obolibrary.org/obo/GO_0006352 goslim_yeast GO:0006350 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006350 CHEBI:32197 biolink:ChemicalSubstance tetracenomycin A2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_32197 chebi_ph7_3 GO:0070989 biolink:BiologicalProcess oxidative demethylation The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0070989 goslim_chembl GO:0070987 biolink:BiologicalProcess error-free translesion synthesis The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level. go-plus.json http://purl.obolibrary.org/obo/GO_0070987 GO:0070988 biolink:BiologicalProcess demethylation The process of removing one or more methyl groups from a molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070988 GO:0070985 biolink:CellularComponent transcription factor TFIIK complex A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7. go-plus.json cyclin H-CDK7 complex|Mcs6/Mcs2/Pmh1 complex|TFIIK complex http://purl.obolibrary.org/obo/GO_0070985 GO:0021974 biolink:BiologicalProcess trigeminothalamic tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face. go-plus.json http://purl.obolibrary.org/obo/GO_0021974 GO:0021975 biolink:BiologicalProcess pons reticulospinal tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021975 GO:0070986 biolink:BiologicalProcess left/right axis specification The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes). go-plus.json left-right axis specification|left/right axis determination http://purl.obolibrary.org/obo/GO_0070986 GO:0021976 biolink:BiologicalProcess medulla reticulospinal tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021976 GO:0070983 biolink:BiologicalProcess dendrite guidance The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json dendritic guidance http://purl.obolibrary.org/obo/GO_0070983 GO:0021977 biolink:BiologicalProcess tectospinal tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021977 GO:0070984 biolink:MolecularActivity SET domain binding Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation. go-plus.json SET binding http://purl.obolibrary.org/obo/GO_0070984 GO:0021978 biolink:BiologicalProcess telencephalon regionalization The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops. go-plus.json http://purl.obolibrary.org/obo/GO_0021978 GO:0070981 biolink:BiologicalProcess L-asparagine biosynthetic process The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid. go-plus.json L-asparagine formation|L-asparagine anabolism|L-asparagine synthesis|L-asparagine biosynthesis http://purl.obolibrary.org/obo/GO_0070981 GO:0021979 biolink:BiologicalProcess hypothalamus cell differentiation The differentiation of cells that will contribute to the structure and function of the hypothalamus. go-plus.json http://purl.obolibrary.org/obo/GO_0021979 GO:0070982 biolink:BiologicalProcess L-asparagine metabolic process The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid. go-plus.json L-asparagine metabolism http://purl.obolibrary.org/obo/GO_0070982 GO:0070980 biolink:BiologicalProcess biphenyl catabolic process The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs). go-plus.json biphenyl breakdown|biphenyl catabolism|biphenyl degradation http://purl.obolibrary.org/obo/GO_0070980 GO:0006328 biolink:BiologicalProcess obsolete AT binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json AT binding http://purl.obolibrary.org/obo/GO_0006328 GO:0006329 biolink:BiologicalProcess obsolete satellite DNA binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json satellite DNA binding http://purl.obolibrary.org/obo/GO_0006329 GO:0006326 biolink:BiologicalProcess obsolete bent DNA binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json bent DNA binding http://purl.obolibrary.org/obo/GO_0006326 GO:0021960 biolink:BiologicalProcess anterior commissure morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum. go-plus.json http://purl.obolibrary.org/obo/GO_0021960 GO:0006327 biolink:BiologicalProcess obsolete random coil binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json random coil binding http://purl.obolibrary.org/obo/GO_0006327 GO:0006324 biolink:BiologicalProcess obsolete S phase-specific histone modification OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle. go-plus.json S phase-specific histone modification|S-phase-specific histone modification http://purl.obolibrary.org/obo/GO_0006324 GO:0021961 biolink:BiologicalProcess posterior commissure morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0021961 GO:0006325 biolink:BiologicalProcess chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. go-plus.json establishment or maintenance of chromatin architecture|chromatin organisation|chromatin modification http://purl.obolibrary.org/obo/GO_0006325 goslim_pombe|goslim_yeast GO:0021962 biolink:BiologicalProcess vestibulospinal tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021962 GO:0006322 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006322 GO:0006323 biolink:BiologicalProcess DNA packaging Any process in which DNA and associated proteins are formed into a compact, orderly structure. go-plus.json DNA organisation|DNA organization|DNA condensation http://purl.obolibrary.org/obo/GO_0006323 goslim_pir GO:0006320 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006320 GO:0006321 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006321 CHEBI:32167 biolink:ChemicalSubstance 1,2-diacyl-3-(alpha-D-6-sulfoquinovosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_32167 GO:0021963 biolink:BiologicalProcess spinothalamic tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling. go-plus.json dorsolateral tract of Lissauer morphogenesis http://purl.obolibrary.org/obo/GO_0021963 GO:0021964 biolink:BiologicalProcess rubrospinal tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021964 GO:0021965 biolink:BiologicalProcess spinal cord ventral commissure morphogenesis The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0021965 GO:0021966 biolink:BiologicalProcess corticospinal neuron axon guidance The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding http://purl.obolibrary.org/obo/GO_0021966 GO:0021967 biolink:BiologicalProcess corticospinal neuron axon guidance through the cerebral cortex The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding through the cerebral cortex http://purl.obolibrary.org/obo/GO_0021967 GO:0021968 biolink:BiologicalProcess corticospinal neuron axon guidance through the internal capsule The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding through the internal capsule http://purl.obolibrary.org/obo/GO_0021968 CHEBI:141828 biolink:ChemicalSubstance 3-hydroxy-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_141828 chebi_ph7_3 GO:0021969 biolink:BiologicalProcess corticospinal neuron axon guidance through the cerebral peduncle The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues. go-plus.json corticospinal neuron axon pathfinding through the cerebral peduncle http://purl.obolibrary.org/obo/GO_0021969 GO:0006339 biolink:BiologicalProcess obsolete positive regulation of transcription of homeotic gene (trithorax group) OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the trithorax group. go-plus.json positive regulation of transcription of homeotic gene (trithorax group) http://purl.obolibrary.org/obo/GO_0006339 GO:0006337 biolink:BiologicalProcess nucleosome disassembly The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006337 GO:0006338 biolink:BiologicalProcess chromatin remodeling Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. go-plus.json chromatin modeling|chromatin remodelling|ATP-dependent chromatin remodelling|chromatin modelling|ATP-dependent chromatin remodeling http://purl.obolibrary.org/obo/GO_0006338 GO:0021950 biolink:BiologicalProcess chemorepulsion involved in precerebellar neuron migration The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration. go-plus.json negative chemotaxis involved in precerebellar neuron migration http://purl.obolibrary.org/obo/GO_0021950 GO:0006335 biolink:BiologicalProcess DNA replication-dependent nucleosome assembly The formation of nucleosomes on newly replicated DNA, coupled to strand elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0006335 GO:0021951 biolink:BiologicalProcess chemoattraction involved in precerebellar neuron migration The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration. go-plus.json positive chemotaxis involved in precerebellar neuron migration http://purl.obolibrary.org/obo/GO_0021951 GO:0006336 biolink:BiologicalProcess DNA replication-independent nucleosome assembly The formation of nucleosomes outside the context of DNA replication. go-plus.json transcription-coupled nucleosome assembly http://purl.obolibrary.org/obo/GO_0006336 GO:0006333 biolink:BiologicalProcess chromatin assembly or disassembly The formation or destruction of chromatin structures. go-plus.json chromatin assembly/disassembly http://purl.obolibrary.org/obo/GO_0006333 GO:0006334 biolink:BiologicalProcess nucleosome assembly The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. go-plus.json histone chaperone|nucleosome modeling http://purl.obolibrary.org/obo/GO_0006334 GO:0006331 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006331 GO:0006332 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006332 GO:0006330 biolink:BiologicalProcess obsolete single-stranded DNA binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json single-stranded DNA binding http://purl.obolibrary.org/obo/GO_0006330 GO:0021952 biolink:BiologicalProcess central nervous system projection neuron axonogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. go-plus.json central nervous system axon tract development http://purl.obolibrary.org/obo/GO_0021952 GO:0021953 biolink:BiologicalProcess central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0021953 GO:0021954 biolink:BiologicalProcess central nervous system neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0021954 GO:0021955 biolink:BiologicalProcess central nervous system neuron axonogenesis Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021955 GO:0021956 biolink:BiologicalProcess central nervous system interneuron axonogenesis Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region. go-plus.json http://purl.obolibrary.org/obo/GO_0021956 GO:0021957 biolink:BiologicalProcess corticospinal tract morphogenesis Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. go-plus.json CST axonogenesis|corticospinal tract axonogenesis http://purl.obolibrary.org/obo/GO_0021957 GO:0021958 biolink:BiologicalProcess gracilis tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb. go-plus.json tract of Goll morphogenesis http://purl.obolibrary.org/obo/GO_0021958 CHEBI:141817 biolink:ChemicalSubstance 5-hydroxy-L-lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_141817 chebi_ph7_3 GO:0021959 biolink:BiologicalProcess cuneatus tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb. go-plus.json tract of Burdach morphogenesis http://purl.obolibrary.org/obo/GO_0021959 GO:0045916 biolink:BiologicalProcess negative regulation of complement activation Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation. go-plus.json down-regulation of complement activation|inhibition of complement activation|negative regulation of complement cascade|down regulation of complement activation|downregulation of complement activation http://purl.obolibrary.org/obo/GO_0045916 GO:0045917 biolink:BiologicalProcess positive regulation of complement activation Any process that activates or increases the frequency, rate or extent of complement activation. go-plus.json activation of complement activation|stimulation of complement activation|up-regulation of complement activation|positive regulation of complement cascade|upregulation of complement activation|up regulation of complement activation http://purl.obolibrary.org/obo/GO_0045917 GO:0045914 biolink:BiologicalProcess negative regulation of catecholamine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. go-plus.json down regulation of catecholamine metabolic process|downregulation of catecholamine metabolic process|down-regulation of catecholamine metabolic process|negative regulation of catecholamine metabolism|inhibition of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0045914 GO:0045915 biolink:BiologicalProcess positive regulation of catecholamine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. go-plus.json up regulation of catecholamine metabolic process|activation of catecholamine metabolic process|stimulation of catecholamine metabolic process|up-regulation of catecholamine metabolic process|positive regulation of catecholamine metabolism|upregulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0045915 GO:0045912 biolink:BiologicalProcess negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. go-plus.json down-regulation of carbohydrate metabolic process|downregulation of carbohydrate metabolic process|down regulation of carbohydrate metabolic process|inhibition of carbohydrate metabolic process|negative regulation of carbohydrate metabolism http://purl.obolibrary.org/obo/GO_0045912 GO:0045913 biolink:BiologicalProcess positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. go-plus.json up regulation of carbohydrate metabolic process|upregulation of carbohydrate metabolic process|stimulation of carbohydrate metabolic process|positive regulation of carbohydrate metabolism|up-regulation of carbohydrate metabolic process|activation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0045913 GO:0045910 biolink:BiologicalProcess negative regulation of DNA recombination Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination. go-plus.json inhibition of DNA recombination|down regulation of DNA recombination|downregulation of DNA recombination|down-regulation of DNA recombination http://purl.obolibrary.org/obo/GO_0045910 GO:0045911 biolink:BiologicalProcess positive regulation of DNA recombination Any process that activates or increases the frequency, rate or extent of DNA recombination. go-plus.json up-regulation of DNA recombination|upregulation of DNA recombination|up regulation of DNA recombination|activation of DNA recombination|stimulation of DNA recombination http://purl.obolibrary.org/obo/GO_0045911 GO:0045918 biolink:BiologicalProcess negative regulation of cytolysis Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis. go-plus.json down regulation of cytolysis|downregulation of cytolysis|down-regulation of cytolysis|inhibition of cytolysis http://purl.obolibrary.org/obo/GO_0045918 GO:0045919 biolink:BiologicalProcess positive regulation of cytolysis Any process that activates or increases the frequency, rate or extent of cytolysis. go-plus.json upregulation of cytolysis|up regulation of cytolysis|activation of cytolysis|stimulation of cytolysis|up-regulation of cytolysis http://purl.obolibrary.org/obo/GO_0045919 GO:0045920 biolink:BiologicalProcess negative regulation of exocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. go-plus.json down regulation of exocytosis|inhibition of exocytosis|down-regulation of exocytosis|downregulation of exocytosis http://purl.obolibrary.org/obo/GO_0045920 GO:0045927 biolink:BiologicalProcess positive regulation of growth Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. go-plus.json up regulation of growth|upregulation of growth|stimulation of growth|up-regulation of growth|activation of growth http://purl.obolibrary.org/obo/GO_0045927 GO:0045928 biolink:BiologicalProcess negative regulation of juvenile hormone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. go-plus.json inhibition of juvenile hormone metabolic process|negative regulation of juvenile hormone metabolism|down-regulation of juvenile hormone metabolic process|downregulation of juvenile hormone metabolic process|down regulation of juvenile hormone metabolic process http://purl.obolibrary.org/obo/GO_0045928 GO:0045925 biolink:BiologicalProcess positive regulation of female receptivity Any process that activates or increases the receptiveness of a female to male advances. go-plus.json upregulation of female receptivity|stimulation of female receptivity|up-regulation of female receptivity|activation of female receptivity|up regulation of female receptivity http://purl.obolibrary.org/obo/GO_0045925 GO:0045926 biolink:BiologicalProcess negative regulation of growth Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. go-plus.json downregulation of growth|down regulation of growth|inhibition of growth|down-regulation of growth http://purl.obolibrary.org/obo/GO_0045926 GO:0045923 biolink:BiologicalProcess positive regulation of fatty acid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. go-plus.json up regulation of fatty acid metabolic process|positive regulation of fatty acid metabolism|upregulation of fatty acid metabolic process|stimulation of fatty acid metabolic process|activation of fatty acid metabolic process|up-regulation of fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0045923 GO:0045924 biolink:BiologicalProcess regulation of female receptivity Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances. go-plus.json female receptivity http://purl.obolibrary.org/obo/GO_0045924 GO:0045921 biolink:BiologicalProcess positive regulation of exocytosis Any process that activates or increases the frequency, rate or extent of exocytosis. go-plus.json upregulation of exocytosis|stimulation of exocytosis|up-regulation of exocytosis|activation of exocytosis|up regulation of exocytosis http://purl.obolibrary.org/obo/GO_0045921 GO:0045922 biolink:BiologicalProcess negative regulation of fatty acid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. go-plus.json down-regulation of fatty acid metabolic process|downregulation of fatty acid metabolic process|down regulation of fatty acid metabolic process|inhibition of fatty acid metabolic process|negative regulation of fatty acid metabolism http://purl.obolibrary.org/obo/GO_0045922 GO:0045929 biolink:BiologicalProcess positive regulation of juvenile hormone metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. go-plus.json upregulation of juvenile hormone metabolic process|positive regulation of juvenile hormone metabolism|stimulation of juvenile hormone metabolic process|up-regulation of juvenile hormone metabolic process|activation of juvenile hormone metabolic process|up regulation of juvenile hormone metabolic process http://purl.obolibrary.org/obo/GO_0045929 GO:0045930 biolink:BiologicalProcess negative regulation of mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. go-plus.json down-regulation of progression through mitotic cell cycle|negative regulation of mitotic cell cycle progression|downregulation of progression through mitotic cell cycle|down regulation of progression through mitotic cell cycle|inhibition of progression through mitotic cell cycle|negative regulation of progression through mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045930 GO:0045931 biolink:BiologicalProcess positive regulation of mitotic cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. go-plus.json up regulation of progression through mitotic cell cycle|positive regulation of mitotic cell cycle progression|upregulation of progression through mitotic cell cycle|stimulation of progression through mitotic cell cycle|up-regulation of progression through mitotic cell cycle|positive regulation of progression through mitotic cell cycle|activation of progression through mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045931 GO:0045938 biolink:BiologicalProcess positive regulation of circadian sleep/wake cycle, sleep Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. go-plus.json upregulation of circadian sleep/wake cycle, sleep|up regulation of circadian sleep/wake cycle, sleep|activation of circadian sleep/wake cycle, sleep|stimulation of circadian sleep/wake cycle, sleep|positive regulation of sleep|up-regulation of circadian sleep/wake cycle, sleep http://purl.obolibrary.org/obo/GO_0045938 GO:0045939 biolink:BiologicalProcess negative regulation of steroid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. go-plus.json down regulation of steroid metabolic process|negative regulation of steroid metabolism|downregulation of steroid metabolic process|down-regulation of steroid metabolic process|inhibition of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045939 GO:0045936 biolink:BiologicalProcess negative regulation of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. go-plus.json down regulation of phosphate metabolic process|downregulation of phosphate metabolic process|negative regulation of phosphate metabolism|down-regulation of phosphate metabolic process|inhibition of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0045936 GO:0045937 biolink:BiologicalProcess positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. go-plus.json upregulation of phosphate metabolic process|up regulation of phosphate metabolic process|activation of phosphate metabolic process|stimulation of phosphate metabolic process|positive regulation of phosphate metabolism|up-regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0045937 GO:0045934 biolink:BiologicalProcess negative regulation of nucleobase-containing compound metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. go-plus.json downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0045934 GO:0045935 biolink:BiologicalProcess positive regulation of nucleobase-containing compound metabolic process Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. go-plus.json positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0045935 GO:0045932 biolink:BiologicalProcess negative regulation of muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. go-plus.json down-regulation of muscle contraction|downregulation of muscle contraction|down regulation of muscle contraction|inhibition of muscle contraction http://purl.obolibrary.org/obo/GO_0045932 GO:0045933 biolink:BiologicalProcess positive regulation of muscle contraction Any process that activates or increases the frequency, rate or extent of muscle contraction. go-plus.json stimulation of muscle contraction|up-regulation of muscle contraction|activation of muscle contraction|up regulation of muscle contraction|upregulation of muscle contraction http://purl.obolibrary.org/obo/GO_0045933 CHEBI:606565 biolink:ChemicalSubstance N-benzoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_606565 chebi_ph7_3 CHEBI:606564 biolink:ChemicalSubstance prostaglandin E2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_606564 chebi_ph7_3 GO:0045941 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045941 GO:0045942 biolink:BiologicalProcess negative regulation of phosphorus utilization Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization. go-plus.json down-regulation of phosphorus utilization|downregulation of phosphorus utilization|down regulation of phosphorus utilization|inhibition of phosphorus utilization http://purl.obolibrary.org/obo/GO_0045942 OBO:GOCHE_37845 biolink:OntologyClass substance with growth hormone role go-plus.json http://purl.obolibrary.org/obo/GOCHE_37845 3_STAR GO:0045940 biolink:BiologicalProcess positive regulation of steroid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. go-plus.json up-regulation of steroid metabolic process|upregulation of steroid metabolic process|positive regulation of steroid metabolism|up regulation of steroid metabolic process|activation of steroid metabolic process|stimulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045940 GO:0031391 biolink:CellularComponent Elg1 RFC-like complex A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p. go-plus.json Elg1-RLC|RFC (Elg1)|Elg1-RFC http://purl.obolibrary.org/obo/GO_0031391 GO:0045949 biolink:BiologicalProcess positive regulation of phosphorus utilization Any process that activates or increases the frequency, rate or extent of phosphorus utilization. go-plus.json stimulation of phosphorus utilization|up-regulation of phosphorus utilization|activation of phosphorus utilization|up regulation of phosphorus utilization|upregulation of phosphorus utilization http://purl.obolibrary.org/obo/GO_0045949 GO:0031392 biolink:BiologicalProcess regulation of prostaglandin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. go-plus.json regulation of prostaglandin anabolism|regulation of prostaglandin synthesis|regulation of prostaglandin formation|regulation of prostaglandin biosynthesis http://purl.obolibrary.org/obo/GO_0031392 GO:0045947 biolink:BiologicalProcess negative regulation of translational initiation Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. go-plus.json down-regulation of translational initiation|downregulation of translational initiation|down regulation of translational initiation|inhibition of translational initiation http://purl.obolibrary.org/obo/GO_0045947 GO:0031390 biolink:CellularComponent Ctf18 RFC-like complex A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p. go-plus.json RFC (Ctf18)|Ctf18-RFC|Ctf18-RLC http://purl.obolibrary.org/obo/GO_0031390 GO:0045948 biolink:BiologicalProcess positive regulation of translational initiation Any process that activates or increases the frequency, rate or extent of translational initiation. go-plus.json up regulation of translational initiation|upregulation of translational initiation|stimulation of translational initiation|up-regulation of translational initiation|activation of translational initiation http://purl.obolibrary.org/obo/GO_0045948 GO:0045945 biolink:BiologicalProcess positive regulation of transcription by RNA polymerase III Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III. go-plus.json positive regulation of transcription from RNA polymerase III promoter|up regulation of transcription from RNA polymerase III promoter|upregulation of transcription from RNA polymerase III promoter|positive regulation of transcription from Pol III promoter|stimulation of transcription from RNA polymerase III promoter|up-regulation of transcription from RNA polymerase III promoter|activation of transcription from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_0045945 GO:0045946 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045946 GO:0045943 biolink:BiologicalProcess positive regulation of transcription by RNA polymerase I Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I. go-plus.json positive regulation of transcription from RNA polymerase I promoter|up regulation of transcription from RNA polymerase I promoter|upregulation of transcription from RNA polymerase I promoter|positive regulation of transcription from Pol I promoter|stimulation of transcription from RNA polymerase I promoter|up-regulation of transcription from RNA polymerase I promoter|activation of transcription from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0045943 GO:0045944 biolink:BiologicalProcess positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json up-regulation of global transcription from RNA polymerase II promoter|activation of transcription from RNA polymerase II promoter|stimulation of transcription from RNA polymerase II promoter|activation of global transcription from RNA polymerase II promoter|positive regulation of global transcription from Pol II promoter|up-regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, global|positive regulation of transcription from Pol II promoter|up regulation of global transcription from RNA polymerase II promoter|upregulation of transcription from RNA polymerase II promoter|upregulation of global transcription from RNA polymerase II promoter|positive regulation of gene-specific transcription from RNA polymerase II promoter|stimulation of global transcription from RNA polymerase II promoter|up regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0045944 GO:0031399 biolink:BiologicalProcess regulation of protein modification process Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031399 goslim_yeast GO:0031397 biolink:BiologicalProcess negative regulation of protein ubiquitination Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein. go-plus.json down-regulation of protein ubiquitination|downregulation of protein ubiquitination|down regulation of protein ubiquitination|inhibition of protein ubiquitination http://purl.obolibrary.org/obo/GO_0031397 GO:0031398 biolink:BiologicalProcess positive regulation of protein ubiquitination Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein. go-plus.json upregulation of protein ubiquitination|stimulation of protein ubiquitination|up-regulation of protein ubiquitination|activation of protein ubiquitination|up regulation of protein ubiquitination http://purl.obolibrary.org/obo/GO_0031398 GO:0031395 biolink:CellularComponent bursicon neuropeptide hormone complex A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0031395 GO:0031396 biolink:BiologicalProcess regulation of protein ubiquitination Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031396 GO:0031393 biolink:BiologicalProcess negative regulation of prostaglandin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. go-plus.json down-regulation of prostaglandin biosynthetic process|negative regulation of prostaglandin biosynthesis|negative regulation of prostaglandin anabolism|downregulation of prostaglandin biosynthetic process|negative regulation of prostaglandin synthesis|down regulation of prostaglandin biosynthetic process|negative regulation of prostaglandin formation|inhibition of prostaglandin biosynthetic process http://purl.obolibrary.org/obo/GO_0031393 GO:0031394 biolink:BiologicalProcess positive regulation of prostaglandin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. go-plus.json up-regulation of prostaglandin biosynthetic process|activation of prostaglandin biosynthetic process|positive regulation of prostaglandin biosynthesis|positive regulation of prostaglandin anabolism|up regulation of prostaglandin biosynthetic process|positive regulation of prostaglandin synthesis|positive regulation of prostaglandin formation|upregulation of prostaglandin biosynthetic process|stimulation of prostaglandin biosynthetic process http://purl.obolibrary.org/obo/GO_0031394 GO:0045952 biolink:BiologicalProcess regulation of juvenile hormone catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. go-plus.json regulation of juvenile hormone degradation|regulation of juvenile hormone catabolism|regulation of juvenile hormone breakdown http://purl.obolibrary.org/obo/GO_0045952 GO:0045953 biolink:BiologicalProcess negative regulation of natural killer cell mediated cytotoxicity Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity. go-plus.json negative regulation of natural killer cell mediated cell death|down regulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cytolysis|downregulation of natural killer cell mediated cytotoxicity|negative regulation of NK cell mediated cytolysis|negative regulation of NK cell mediated cytotoxicity|negative regulation of NK cell mediated cell killing|down-regulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cell killing|inhibition of natural killer cell mediated cytotoxicity|negative regulation of NK cell mediated cell death http://purl.obolibrary.org/obo/GO_0045953 GO:0045950 biolink:BiologicalProcess negative regulation of mitotic recombination Any process that inhibits or decreases the rate of DNA recombination during mitosis. go-plus.json down regulation of mitotic recombination|downregulation of mitotic recombination|negative regulation of recombination within rDNA repeats|down-regulation of mitotic recombination|inhibition of mitotic recombination http://purl.obolibrary.org/obo/GO_0045950 GO:0045951 biolink:BiologicalProcess positive regulation of mitotic recombination Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis. go-plus.json upregulation of mitotic recombination|up regulation of mitotic recombination|positive regulation of recombination within rDNA repeats|activation of mitotic recombination|stimulation of mitotic recombination|up-regulation of mitotic recombination http://purl.obolibrary.org/obo/GO_0045951 GO:0070909 biolink:MolecularActivity glutamate:gamma-aminobutyric acid antiporter activity Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out). go-plus.json glutamate-gamma-aminobutyric acid antiporter activity|glutamate/gamma-aminobutyric acid antiporter activity|glutamate: GABA antiporter activity http://purl.obolibrary.org/obo/GO_0070909 NCBITaxon:9903 biolink:OrganismalEntity Bos go-plus.json oxen, cattle http://purl.obolibrary.org/obo/NCBITaxon_9903 GO:0070907 biolink:MolecularActivity histidine:histamine antiporter activity Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out). go-plus.json histidine-histamine antiporter activity|histidine/histamine antiporter activity http://purl.obolibrary.org/obo/GO_0070907 NCBITaxon:2785018 biolink:OrganismalEntity Camarodonta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2785018 GO:0070908 biolink:MolecularActivity tyrosine:tyramine antiporter activity Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out). go-plus.json tyrosine/tyramine antiporter activity|tyrosine-tyramine antiporter activity http://purl.obolibrary.org/obo/GO_0070908 GO:0070916 biolink:CellularComponent inositol phosphoceramide synthase complex A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces). go-plus.json IPC synthase complex http://purl.obolibrary.org/obo/GO_0070916 GO:0031380 biolink:CellularComponent nuclear RNA-directed RNA polymerase complex A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain. go-plus.json Rdr1 complex|RDRC http://purl.obolibrary.org/obo/GO_0031380 GO:0070917 biolink:MolecularActivity inositol phosphoceramide synthase regulator activity Binds to and modulates the activity of inositol phosphoceramide synthase. go-plus.json IPC synthase regulator activity http://purl.obolibrary.org/obo/GO_0070917 GO:0031381 biolink:CellularComponent viral RNA-directed RNA polymerase complex A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus. go-plus.json http://purl.obolibrary.org/obo/GO_0031381 GO:0045958 biolink:BiologicalProcess positive regulation of complement activation, alternative pathway Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway. go-plus.json up regulation of complement activation, alternative pathway|upregulation of complement activation, alternative pathway|positive regulation of complement cascade, alternative pathway|stimulation of complement activation, alternative pathway|up-regulation of complement activation, alternative pathway|activation of complement activation, alternative pathway http://purl.obolibrary.org/obo/GO_0045958 GO:0070914 biolink:BiologicalProcess UV-damage excision repair A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). go-plus.json UV-damaged DNA endonuclease-dependent excision repair|UVDE-dependent excision repair|UVER|AER|alternative excision repair http://purl.obolibrary.org/obo/GO_0070914 GO:0045959 biolink:BiologicalProcess negative regulation of complement activation, classical pathway Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway. go-plus.json negative regulation of complement cascade, classical pathway|down-regulation of complement activation, classical pathway|downregulation of complement activation, classical pathway|down regulation of complement activation, classical pathway|inhibition of complement activation, classical pathway http://purl.obolibrary.org/obo/GO_0045959 GO:0070915 biolink:MolecularActivity lysophosphatidic acid receptor activity Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json LPA receptor activity http://purl.obolibrary.org/obo/GO_0070915 GO:0045956 biolink:BiologicalProcess positive regulation of calcium ion-dependent exocytosis Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis. go-plus.json activation of calcium ion-dependent exocytosis|up regulation of calcium ion-dependent exocytosis|upregulation of calcium ion-dependent exocytosis|stimulation of calcium ion-dependent exocytosis|up-regulation of calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_0045956 GO:0070912 biolink:CellularComponent Ddb1-Ckn1 complex A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases. go-plus.json http://purl.obolibrary.org/obo/GO_0070912 GO:0045957 biolink:BiologicalProcess negative regulation of complement activation, alternative pathway Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway. go-plus.json downregulation of complement activation, alternative pathway|down regulation of complement activation, alternative pathway|inhibition of complement activation, alternative pathway|negative regulation of complement cascade, alternative pathway|down-regulation of complement activation, alternative pathway http://purl.obolibrary.org/obo/GO_0045957 GO:0070913 biolink:CellularComponent Ddb1-Wdr21 complex A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases. go-plus.json http://purl.obolibrary.org/obo/GO_0070913 GO:0045954 biolink:BiologicalProcess positive regulation of natural killer cell mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. go-plus.json positive regulation of natural killer cell mediated cell death|upregulation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytolysis|positive regulation of NK cell mediated cell killing|up regulation of natural killer cell mediated cytotoxicity|activation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cytolysis|positive regulation of natural killer cell mediated cell killing|stimulation of natural killer cell mediated cytotoxicity|up-regulation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cell death http://purl.obolibrary.org/obo/GO_0045954 GO:0070910 biolink:BiologicalProcess cell wall macromolecule catabolic process involved in cell wall disassembly The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0070910 GO:0070911 biolink:BiologicalProcess global genome nucleotide-excision repair The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome. go-plus.json GG-NER|global genomic repair|global genome NER|global genomic nucleotide-excision repair|GGR http://purl.obolibrary.org/obo/GO_0070911 GO:0045955 biolink:BiologicalProcess negative regulation of calcium ion-dependent exocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis. go-plus.json down-regulation of calcium ion-dependent exocytosis|downregulation of calcium ion-dependent exocytosis|down regulation of calcium ion-dependent exocytosis|inhibition of calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_0045955 GO:0031388 biolink:BiologicalProcess organic acid phosphorylation The process of introducing one or more phosphate groups into an organic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0031388 GO:0031389 biolink:CellularComponent Rad17 RFC-like complex A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p. go-plus.json Rad17-RFC|Rad17-RLC|Rad24p RFC-like complex|RFC (Rad17) http://purl.obolibrary.org/obo/GO_0031389 GO:0031386 biolink:MolecularActivity protein tag A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation. go-plus.json ubiquitin-like protein modifier|protein tagging activity|covalent modifier|ubiquitin http://purl.obolibrary.org/obo/GO_0031386 goslim_pir GO:0031387 biolink:CellularComponent MPF complex A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC). go-plus.json http://purl.obolibrary.org/obo/GO_0031387 GO:0031384 biolink:BiologicalProcess regulation of initiation of mating projection growth Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0031384 GO:0031385 biolink:BiologicalProcess regulation of termination of mating projection growth Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0031385 GO:0031382 biolink:BiologicalProcess mating projection formation The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi. go-plus.json mating projection assembly|shmooing|mating projection biogenesis http://purl.obolibrary.org/obo/GO_0031382 GO:0031383 biolink:BiologicalProcess regulation of mating projection assembly Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi. go-plus.json regulation of mating projection biogenesis http://purl.obolibrary.org/obo/GO_0031383 GO:0031379 biolink:CellularComponent RNA-directed RNA polymerase complex A protein complex that possesses RNA-directed RNA polymerase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0031379 GO:0045963 biolink:BiologicalProcess negative regulation of dopamine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine. go-plus.json down-regulation of dopamine metabolic process|downregulation of dopamine metabolic process|down regulation of dopamine metabolic process|inhibition of dopamine metabolic process|negative regulation of dopamine metabolism http://purl.obolibrary.org/obo/GO_0045963 GO:0045964 biolink:BiologicalProcess positive regulation of dopamine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine. go-plus.json stimulation of dopamine metabolic process|activation of dopamine metabolic process|up-regulation of dopamine metabolic process|up regulation of dopamine metabolic process|upregulation of dopamine metabolic process|positive regulation of dopamine metabolism http://purl.obolibrary.org/obo/GO_0045964 GO:0045961 biolink:BiologicalProcess negative regulation of development, heterochronic Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached. go-plus.json down-regulation of development, heterochronic|downregulation of development, heterochronic|down regulation of development, heterochronic|inhibition of development, heterochronic http://purl.obolibrary.org/obo/GO_0045961 NCBITaxon:9913 biolink:OrganismalEntity Bos taurus go-plus.json dairy cow|domestic cattle|bovine|cattle|Bos bovis|cow|domestic cow|Bos primigenius taurus http://purl.obolibrary.org/obo/NCBITaxon_9913 GO:0045962 biolink:BiologicalProcess positive regulation of development, heterochronic Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached. go-plus.json upregulation of development, heterochronic|stimulation of development, heterochronic|activation of development, heterochronic|up-regulation of development, heterochronic|up regulation of development, heterochronic http://purl.obolibrary.org/obo/GO_0045962 GO:0045960 biolink:BiologicalProcess positive regulation of complement activation, classical pathway Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway. go-plus.json upregulation of complement activation, classical pathway|positive regulation of complement cascade, classical pathway|stimulation of complement activation, classical pathway|activation of complement activation, classical pathway|up-regulation of complement activation, classical pathway|up regulation of complement activation, classical pathway http://purl.obolibrary.org/obo/GO_0045960 GO:0070905 biolink:MolecularActivity serine binding Binding to 2-amino-3-hydroxypropanoic acid. go-plus.json Ser binding http://purl.obolibrary.org/obo/GO_0070905 GO:0070906 biolink:MolecularActivity aspartate:alanine antiporter activity Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out). RHEA:33139 go-plus.json aspartate-alanine antiporter activity|aspartate/alanine antiporter activity http://purl.obolibrary.org/obo/GO_0070906 GO:0031370 biolink:MolecularActivity eukaryotic initiation factor 4G binding Binding to eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation. go-plus.json eIF4G binding http://purl.obolibrary.org/obo/GO_0031370 GO:0045969 biolink:BiologicalProcess positive regulation of juvenile hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. go-plus.json stimulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone formation|up-regulation of juvenile hormone biosynthetic process|upregulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone anabolism|up regulation of juvenile hormone biosynthetic process|activation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone biosynthesis|positive regulation of juvenile hormone synthesis http://purl.obolibrary.org/obo/GO_0045969 GO:0070903 biolink:BiologicalProcess mitochondrial tRNA thio-modification The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070903 GO:0070904 biolink:BiologicalProcess transepithelial L-ascorbic acid transport The directed movement of L-ascorbic acid from one side of an epithelium to the other. go-plus.json transepithelial L-ascorbate transport|transepithelial vitamin C transport http://purl.obolibrary.org/obo/GO_0070904 GO:0070901 biolink:BiologicalProcess mitochondrial tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070901 GO:0045967 biolink:BiologicalProcess negative regulation of growth rate Any process that reduces the rate of growth of all or part of an organism. go-plus.json down-regulation of growth rate|inhibition of growth rate|down regulation of growth rate|downregulation of growth rate http://purl.obolibrary.org/obo/GO_0045967 GO:0045968 biolink:BiologicalProcess negative regulation of juvenile hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. go-plus.json negative regulation of juvenile hormone biosynthesis|down-regulation of juvenile hormone biosynthetic process|inhibition of juvenile hormone biosynthetic process|down regulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone anabolism|downregulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone synthesis|negative regulation of juvenile hormone formation http://purl.obolibrary.org/obo/GO_0045968 GO:0070902 biolink:BiologicalProcess mitochondrial tRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070902 GO:0045965 biolink:BiologicalProcess negative regulation of ecdysteroid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids. go-plus.json down regulation of ecdysteroid metabolic process|downregulation of ecdysteroid metabolic process|down-regulation of ecdysteroid metabolic process|inhibition of ecdysteroid metabolic process|negative regulation of ecdysteroid metabolism http://purl.obolibrary.org/obo/GO_0045965 GO:0045966 biolink:BiologicalProcess positive regulation of ecdysteroid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids. go-plus.json positive regulation of ecdysteroid metabolism|up regulation of ecdysteroid metabolic process|activation of ecdysteroid metabolic process|stimulation of ecdysteroid metabolic process|up-regulation of ecdysteroid metabolic process|upregulation of ecdysteroid metabolic process http://purl.obolibrary.org/obo/GO_0045966 GO:0070900 biolink:BiologicalProcess mitochondrial tRNA modification The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically. go-plus.json http://purl.obolibrary.org/obo/GO_0070900 GO:0031377 biolink:CellularComponent obsolete mitochondrial type II fatty acid synthase complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion. go-plus.json mitochondrial type II fatty acid synthase complex|mitochondrial type II FAS complex http://purl.obolibrary.org/obo/GO_0031377 GO:0031378 biolink:CellularComponent obsolete plastid type II fatty acid synthase complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid. go-plus.json plastid type II FAS complex|plastid type II fatty acid synthase complex http://purl.obolibrary.org/obo/GO_0031378 GO:0031375 biolink:CellularComponent obsolete type II fatty acid synthase complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity. go-plus.json type II FAS complex|type II fatty acid synthase complex|type II fatty acid synthase|type II FAS http://purl.obolibrary.org/obo/GO_0031375 GO:0031376 biolink:CellularComponent obsolete cytosolic type II fatty acid synthase complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol. go-plus.json cytosolic type II fatty acid synthase complex|cytosolic type II FAS complex http://purl.obolibrary.org/obo/GO_0031376 GO:0031373 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031373 GO:0031374 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031374 GO:0031371 biolink:CellularComponent ubiquitin conjugating enzyme complex Any complex that possesses ubiquitin conjugating enzyme activity. go-plus.json E2 complex http://purl.obolibrary.org/obo/GO_0031371 goslim_pir GO:0031372 biolink:CellularComponent UBC13-MMS2 complex A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p. go-plus.json http://purl.obolibrary.org/obo/GO_0031372 GO:0031368 biolink:MolecularActivity obsolete Pro-X metallocarboxypeptidase activity OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid. EC:3.4.17.16 go-plus.json microsomal carboxypeptidase activity|carboxypeptidase P activity|membrane Pro-X carboxypeptidase activity|membrane Pro-Xaa carboxypeptidase|Pro-X metallocarboxypeptidase activity http://purl.obolibrary.org/obo/GO_0031368 GO:0031369 biolink:MolecularActivity translation initiation factor binding Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation. go-plus.json http://purl.obolibrary.org/obo/GO_0031369 GO:0045974 biolink:BiologicalProcess regulation of translation, ncRNA-mediated Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein. go-plus.json http://purl.obolibrary.org/obo/GO_0045974 GO:0045975 biolink:BiologicalProcess positive regulation of translation, ncRNA-mediated Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein. go-plus.json up regulation of mRNA translation, ncRNA-mediated|upregulation of mRNA translation, ncRNA-mediated|stimulation of mRNA translation, ncRNA-mediated|up-regulation of mRNA translation, ncRNA-mediated|activation of mRNA translation, ncRNA-mediated http://purl.obolibrary.org/obo/GO_0045975 GO:0045972 biolink:BiologicalProcess negative regulation of juvenile hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone. go-plus.json down-regulation of juvenile hormone secretion|downregulation of juvenile hormone secretion|down regulation of juvenile hormone secretion|inhibition of juvenile hormone secretion http://purl.obolibrary.org/obo/GO_0045972 GO:0045973 biolink:BiologicalProcess positive regulation of juvenile hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone. go-plus.json up regulation of juvenile hormone secretion|upregulation of juvenile hormone secretion|stimulation of juvenile hormone secretion|up-regulation of juvenile hormone secretion|activation of juvenile hormone secretion http://purl.obolibrary.org/obo/GO_0045973 GO:0045970 biolink:BiologicalProcess negative regulation of juvenile hormone catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. go-plus.json downregulation of juvenile hormone catabolic process|down regulation of juvenile hormone catabolic process|inhibition of juvenile hormone catabolic process|negative regulation of juvenile hormone catabolism|negative regulation of juvenile hormone degradation|negative regulation of juvenile hormone breakdown|down-regulation of juvenile hormone catabolic process http://purl.obolibrary.org/obo/GO_0045970 GO:0045971 biolink:BiologicalProcess positive regulation of juvenile hormone catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. go-plus.json up regulation of juvenile hormone catabolic process|positive regulation of juvenile hormone catabolism|upregulation of juvenile hormone catabolic process|stimulation of juvenile hormone catabolic process|up-regulation of juvenile hormone catabolic process|activation of juvenile hormone catabolic process|positive regulation of juvenile hormone degradation|positive regulation of juvenile hormone breakdown http://purl.obolibrary.org/obo/GO_0045971 GO:0070929 biolink:BiologicalProcess trans-translation A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0070929 GO:0070938 biolink:CellularComponent contractile ring A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles. go-plus.json constriction ring|cytokinetic ring http://purl.obolibrary.org/obo/GO_0070938 GO:0070939 biolink:CellularComponent Dsl1/NZR complex A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p. go-plus.json CATCHR family complex|Dsl1p complex|NZR complex http://purl.obolibrary.org/obo/GO_0070939 GO:0070936 biolink:BiologicalProcess protein K48-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. go-plus.json protein K48-linked polyubiquitination http://purl.obolibrary.org/obo/GO_0070936 GO:0070937 biolink:CellularComponent CRD-mediated mRNA stability complex A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9. go-plus.json coding-region instability determinant -mediated mRNA stability complex|coding-region determinant of instability-mediated mRNA stability complex http://purl.obolibrary.org/obo/GO_0070937 GO:0045978 biolink:BiologicalProcess negative regulation of nucleoside metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. go-plus.json downregulation of nucleoside metabolic process|down regulation of nucleoside metabolic process|inhibition of nucleoside metabolic process|negative regulation of nucleoside metabolism|down-regulation of nucleoside metabolic process http://purl.obolibrary.org/obo/GO_0045978 GO:0070934 biolink:BiologicalProcess CRD-mediated mRNA stabilization An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD). go-plus.json coding region determinant-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_0070934 GO:0045979 biolink:BiologicalProcess positive regulation of nucleoside metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. go-plus.json up regulation of nucleoside metabolic process|upregulation of nucleoside metabolic process|positive regulation of nucleoside metabolism|stimulation of nucleoside metabolic process|up-regulation of nucleoside metabolic process|activation of nucleoside metabolic process http://purl.obolibrary.org/obo/GO_0045979 GO:0070935 biolink:BiologicalProcess 3'-UTR-mediated mRNA stabilization An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. go-plus.json 3'-untranslated region-mediated mRNA stabilization http://purl.obolibrary.org/obo/GO_0070935 GO:0070932 biolink:BiologicalProcess histone H3 deacetylation The modification of histone H3 by the removal of one or more acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0070932 GO:0045976 biolink:BiologicalProcess negative regulation of mitotic cell cycle, embryonic Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle. go-plus.json down regulation of progression through embryonic mitotic cell cycle|inhibition of progression through embryonic mitotic cell cycle|negative regulation of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle|down-regulation of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle progression|downregulation of progression through embryonic mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045976 GO:0070933 biolink:BiologicalProcess histone H4 deacetylation The modification of histone H4 by the removal of one or more acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0070933 GO:0045977 biolink:BiologicalProcess positive regulation of mitotic cell cycle, embryonic Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle. go-plus.json upregulation of mitotic cell cycle, embryonic|up regulation of mitotic cell cycle, embryonic|positive regulation of progression through embryonic mitotic cell cycle|positive regulation of embryonic mitotic cell cycle|activation of mitotic cell cycle, embryonic|stimulation of mitotic cell cycle, embryonic|up-regulation of mitotic cell cycle, embryonic|positive regulation of embryonic mitotic cell cycle progression http://purl.obolibrary.org/obo/GO_0045977 GO:0070930 biolink:BiologicalProcess trans-translation-dependent protein tagging A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation. go-plus.json protein modification by trans-translation|cotranslational protein tagging|co-translational protein tagging http://purl.obolibrary.org/obo/GO_0070930 GO:0031366 biolink:BiologicalProcess N-terminal peptidyl-asparagine deamination The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031366 GO:0070931 biolink:CellularComponent Golgi-associated vesicle lumen The volume enclosed by the membrane of a Golgi-associated vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0070931 GO:0031367 biolink:BiologicalProcess N-terminal peptidyl-glutamine deamination The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031367 GO:0031364 biolink:BiologicalProcess N-terminal protein amino acid deamination, from side chain The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031364 GO:0031365 biolink:BiologicalProcess N-terminal protein amino acid modification The alteration of the N-terminal amino acid residue in a protein. go-plus.json peptide or protein amino-terminal blocking|peptide/protein amino-terminal blocking http://purl.obolibrary.org/obo/GO_0031365 GO:0031362 biolink:CellularComponent anchored component of external side of plasma membrane The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json anchored to external leaflet of plasma membrane|anchored to external side of plasma membrane http://purl.obolibrary.org/obo/GO_0031362 GO:0031363 biolink:BiologicalProcess N-terminal protein amino acid deamination The removal of an amino group from the N-terminal amino acid residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031363 GO:0031360 biolink:CellularComponent intrinsic component of thylakoid membrane The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to thylakoid membrane http://purl.obolibrary.org/obo/GO_0031360 GO:0031361 biolink:CellularComponent integral component of thylakoid membrane The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to thylakoid membrane http://purl.obolibrary.org/obo/GO_0031361 GO:0031359 biolink:CellularComponent integral component of chloroplast outer membrane The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to chloroplast outer membrane http://purl.obolibrary.org/obo/GO_0031359 GO:0031357 biolink:CellularComponent integral component of chloroplast inner membrane The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to chloroplast inner membrane http://purl.obolibrary.org/obo/GO_0031357 GO:0031358 biolink:CellularComponent intrinsic component of chloroplast outer membrane The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to chloroplast outer membrane http://purl.obolibrary.org/obo/GO_0031358 GO:0045985 biolink:BiologicalProcess positive regulation of pyrimidine nucleobase metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases. go-plus.json up-regulation of pyrimidine base metabolic process|upregulation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolism|up regulation of pyrimidine base metabolic process|activation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolic process|stimulation of pyrimidine base metabolic process http://purl.obolibrary.org/obo/GO_0045985 GO:0045986 biolink:BiologicalProcess negative regulation of smooth muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. go-plus.json inhibition of smooth muscle contraction|down regulation of smooth muscle contraction|downregulation of smooth muscle contraction|smooth muscle relaxation|down-regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0045986 GO:0045983 biolink:BiologicalProcess positive regulation of purine nucleobase metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases. go-plus.json upregulation of purine base metabolic process|up regulation of purine base metabolic process|positive regulation of purine base metabolic process|activation of purine base metabolic process|positive regulation of purine base metabolism|stimulation of purine base metabolic process|up-regulation of purine base metabolic process http://purl.obolibrary.org/obo/GO_0045983 GO:0045984 biolink:BiologicalProcess negative regulation of pyrimidine nucleobase metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases. go-plus.json inhibition of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolism|down regulation of pyrimidine base metabolic process|downregulation of pyrimidine base metabolic process|down-regulation of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolic process http://purl.obolibrary.org/obo/GO_0045984 GO:0045981 biolink:BiologicalProcess positive regulation of nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. go-plus.json up regulation of nucleotide metabolic process|upregulation of nucleotide metabolic process|positive regulation of nucleotide metabolism|stimulation of nucleotide metabolic process|up-regulation of nucleotide metabolic process|activation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045981 GO:0045982 biolink:BiologicalProcess negative regulation of purine nucleobase metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases. go-plus.json down regulation of purine base metabolic process|downregulation of purine base metabolic process|negative regulation of purine base metabolism|down-regulation of purine base metabolic process|negative regulation of purine base metabolic process|inhibition of purine base metabolic process http://purl.obolibrary.org/obo/GO_0045982 GO:0070918 biolink:BiologicalProcess production of small RNA involved in gene silencing by RNA The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease. go-plus.json gene silencing by RNA, production of small RNA|gene silencing by RNA, production of guide RNA http://purl.obolibrary.org/obo/GO_0070918 GO:0070919 biolink:BiologicalProcess production of siRNA involved in gene silencing by small RNA Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA. go-plus.json production of siRNA involved in chromatin silencing by small RNA|chromatin silencing by small RNA, production of siRNA|production of guide RNAs involved in chromatin silencing by small RNA|chromatin silencing by small RNA, production of guide RNAs http://purl.obolibrary.org/obo/GO_0070919 GO:0045980 biolink:BiologicalProcess negative regulation of nucleotide metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. go-plus.json down-regulation of nucleotide metabolic process|downregulation of nucleotide metabolic process|down regulation of nucleotide metabolic process|inhibition of nucleotide metabolic process|negative regulation of nucleotide metabolism http://purl.obolibrary.org/obo/GO_0045980 GO:0070927 biolink:BiologicalProcess negative regulation of ATP:ADP antiporter activity Any process that stops or reduces the activity of an ATP:ADP antiporter. go-plus.json inhibition of ATP:ADP antiporter activity|down regulation of ATP:ADP antiporter activity|downregulation of ATP:ADP antiporter activity|down-regulation of ATP:ADP antiporter activity http://purl.obolibrary.org/obo/GO_0070927 GO:0070928 biolink:BiologicalProcess regulation of mRNA stability, ncRNA-mediated Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs. go-plus.json ncRNA-mediated regulation of mRNA stability|regulation of mRNA stability, non-coding RNA-mediated http://purl.obolibrary.org/obo/GO_0070928 GO:0070925 biolink:BiologicalProcess organelle assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0070925 goslim_yeast GO:0070926 biolink:BiologicalProcess regulation of ATP:ADP antiporter activity Any process that modulates the activity of an ATP:ADP antiporter. go-plus.json http://purl.obolibrary.org/obo/GO_0070926 GO:0070923 biolink:BiologicalProcess siRNA loading onto RISC involved in gene silencing by small RNA The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin gene by small RNA. go-plus.json chromatin silencing by small RNA, siRNA loading onto RISC|siRNA loading onto RISC involved in chromatin silencing by small RNA http://purl.obolibrary.org/obo/GO_0070923 GO:0045989 biolink:BiologicalProcess positive regulation of striated muscle contraction Any process that activates or increases the frequency, rate or extent of striated muscle contraction. go-plus.json up-regulation of striated muscle contraction|upregulation of striated muscle contraction|up regulation of striated muscle contraction|activation of striated muscle contraction|stimulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045989 GO:0070924 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070924 GO:0070921 biolink:BiologicalProcess regulation of production of siRNA involved in gene silencing by small RNA Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA. go-plus.json regulation of chromatin silencing by small RNA, production of siRNA|regulation of production of siRNA involved in chromatin silencing by small RNA http://purl.obolibrary.org/obo/GO_0070921 GO:0045987 biolink:BiologicalProcess positive regulation of smooth muscle contraction Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. go-plus.json up-regulation of smooth muscle contraction|upregulation of smooth muscle contraction|up regulation of smooth muscle contraction|activation of smooth muscle contraction|stimulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0045987 GO:0045988 biolink:BiologicalProcess negative regulation of striated muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. go-plus.json inhibition of striated muscle contraction|down regulation of striated muscle contraction|downregulation of striated muscle contraction|down-regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045988 GO:0070922 biolink:BiologicalProcess small RNA loading onto RISC The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA. go-plus.json RISC assembly|gene silencing by RNA, small RNA loading onto RISC http://purl.obolibrary.org/obo/GO_0070922 GO:0031355 biolink:CellularComponent integral component of plastid outer membrane The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to plastid outer membrane http://purl.obolibrary.org/obo/GO_0031355 GO:0070920 biolink:BiologicalProcess regulation of production of small RNA involved in gene silencing by RNA Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA. go-plus.json regulation of gene silencing by RNA, production of small RNA|regulation of gene silencing by RNA, production of guide RNA http://purl.obolibrary.org/obo/GO_0070920 GO:0031356 biolink:CellularComponent intrinsic component of chloroplast inner membrane The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to chloroplast inner membrane http://purl.obolibrary.org/obo/GO_0031356 GO:0031353 biolink:CellularComponent integral component of plastid inner membrane The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to plastid inner membrane http://purl.obolibrary.org/obo/GO_0031353 GO:0031354 biolink:CellularComponent intrinsic component of plastid outer membrane The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to plastid outer membrane http://purl.obolibrary.org/obo/GO_0031354 GO:0031351 biolink:CellularComponent integral component of plastid membrane The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to plastid membrane http://purl.obolibrary.org/obo/GO_0031351 GO:0031352 biolink:CellularComponent intrinsic component of plastid inner membrane The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to plastid inner membrane http://purl.obolibrary.org/obo/GO_0031352 GO:0031350 biolink:CellularComponent intrinsic component of plastid membrane The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to plastid membrane http://purl.obolibrary.org/obo/GO_0031350 CHEBI:22743 biolink:ChemicalSubstance benzyl alcohols go-plus.json http://purl.obolibrary.org/obo/CHEBI_22743 CHEBI:22744 biolink:ChemicalSubstance benzyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22744 chebi_ph7_3 CHEBI:22748 biolink:ChemicalSubstance benzyl 2-methyl-3-hydroxybutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22748 chebi_ph7_3 CHEBI:22746 biolink:ChemicalSubstance 2-benzylsuccinyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_22746 CHEBI:22750 biolink:ChemicalSubstance benzylisoquinoline alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22750 CHEBI:22754 biolink:ChemicalSubstance berberine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22754 CHEBI:46700 biolink:ChemicalSubstance benzoxazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_46700 CHEBI:46701 biolink:ChemicalSubstance pyrrolidinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46701 CHEBI:46702 biolink:ChemicalSubstance (-)-geosmin go-plus.json http://purl.obolibrary.org/obo/CHEBI_46702 chebi_ph7_3 NCBITaxon:559292 biolink:OrganismalEntity Saccharomyces cerevisiae S288C go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_559292 CHEBI:46703 biolink:ChemicalSubstance geosmin go-plus.json http://purl.obolibrary.org/obo/CHEBI_46703 CHEBI:46705 biolink:ChemicalSubstance (+)-geosmin go-plus.json http://purl.obolibrary.org/obo/CHEBI_46705 chebi_ph7_3 CHEBI:22720 biolink:ChemicalSubstance benzodiazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22720 CHEBI:22726 biolink:ChemicalSubstance benzophenones go-plus.json http://purl.obolibrary.org/obo/CHEBI_22726 CHEBI:22723 biolink:ChemicalSubstance benzoic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_22723 CHEBI:22729 biolink:ChemicalSubstance benzoquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_22729 CHEBI:22727 biolink:ChemicalSubstance benzopyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_22727 CHEBI:22728 biolink:ChemicalSubstance benzopyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_22728 CHEBI:22730 biolink:ChemicalSubstance benzosemiquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_22730 CHEBI:22731 biolink:ChemicalSubstance 3-oxo-3-phenylpropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22731 chebi_ph7_3 CHEBI:22736 biolink:ChemicalSubstance benzoyl-CoAs go-plus.json http://purl.obolibrary.org/obo/CHEBI_22736 CHEBI:71711 biolink:ChemicalSubstance phosphatidylethanolamine 32:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_71711 chebi_ph7_3 CHEBI:71712 biolink:ChemicalSubstance phosphatidylethanolamine 32:1 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71712 chebi_ph7_3 CHEBI:71713 biolink:ChemicalSubstance phosphatidylethanolamine 32:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_71713 chebi_ph7_3 NCBITaxon:9989 biolink:OrganismalEntity Rodentia go-plus.json rodent|rodents http://purl.obolibrary.org/obo/NCBITaxon_9989 CHEBI:71718 biolink:ChemicalSubstance phosphatidylethanolamine 34:0 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71718 chebi_ph7_3 CHEBI:71719 biolink:ChemicalSubstance 9-ribosyl-trans-zeatin 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71719 CHEBI:4712 biolink:ChemicalSubstance doxercalciferol go-plus.json http://purl.obolibrary.org/obo/CHEBI_4712 chebi_ph7_3 CHEBI:22702 biolink:ChemicalSubstance benzamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_22702 CHEBI:22707 biolink:ChemicalSubstance benzenetriol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22707 CHEBI:22706 biolink:ChemicalSubstance benzenetetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22706 CHEBI:71720 biolink:ChemicalSubstance phosphatidylethanolamine 34:1 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71720 chebi_ph7_3 CHEBI:71721 biolink:ChemicalSubstance phosphatidylethanolamine 34:2 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71721 chebi_ph7_3 CHEBI:71727 biolink:ChemicalSubstance phosphatidylethanolamine 36:1 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71727 chebi_ph7_3 CHEBI:71728 biolink:ChemicalSubstance phosphatidylethanolamine 36:2 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71728 chebi_ph7_3 CHEBI:71729 biolink:ChemicalSubstance phosphatidylethanolamine 36:3 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71729 chebi_ph7_3 CHEBI:22715 biolink:ChemicalSubstance benzimidazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_22715 CHEBI:22712 biolink:ChemicalSubstance benzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_22712 CHEBI:22713 biolink:ChemicalSubstance arenesulfonate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22713 CHEBI:22718 biolink:ChemicalSubstance benzoates go-plus.json http://purl.obolibrary.org/obo/CHEBI_22718 CHEBI:71730 biolink:ChemicalSubstance phosphatidylethanolamine 36:4 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71730 chebi_ph7_3 CHEBI:71737 biolink:ChemicalSubstance phosphatidylethanolamine 38:4 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71737 chebi_ph7_3 CHEBI:71738 biolink:ChemicalSubstance phosphatidylethanolamine 38:5 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71738 chebi_ph7_3 CHEBI:71739 biolink:ChemicalSubstance phosphatidylethanolamine 38:6 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71739 chebi_ph7_3 CHEBI:71746 biolink:ChemicalSubstance phosphatidylethanolamine 40:6 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71746 chebi_ph7_3 NCBITaxon:114656 biolink:OrganismalEntity Funariidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_114656 CHEBI:4705 biolink:ChemicalSubstance double-stranded DNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_4705 GO:0045905 biolink:BiologicalProcess positive regulation of translational termination Any process that activates or increases the frequency, rate or extent of translational termination. go-plus.json activation of translational termination|stimulation of translational termination|up-regulation of translational termination|upregulation of translational termination|up regulation of translational termination http://purl.obolibrary.org/obo/GO_0045905 GO:0045906 biolink:BiologicalProcess negative regulation of vasoconstriction Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction. go-plus.json down-regulation of vasoconstriction|downregulation of vasoconstriction|down regulation of vasoconstriction|inhibition of vasoconstriction http://purl.obolibrary.org/obo/GO_0045906 GO:0045903 biolink:BiologicalProcess positive regulation of translational fidelity Any process that increases the ability of the translational apparatus to interpret the genetic code. go-plus.json up regulation of translational fidelity|upregulation of translational fidelity|stimulation of translational fidelity|up-regulation of translational fidelity|activation of translational fidelity http://purl.obolibrary.org/obo/GO_0045903 GO:0045904 biolink:BiologicalProcess negative regulation of translational termination Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. go-plus.json down-regulation of translational termination|inhibition of translational termination|down regulation of translational termination|downregulation of translational termination http://purl.obolibrary.org/obo/GO_0045904 GO:0045901 biolink:BiologicalProcess positive regulation of translational elongation Any process that activates or increases the frequency, rate or extent of translational elongation. go-plus.json upregulation of translational elongation|stimulation of translational elongation|activation of translational elongation|up-regulation of translational elongation|up regulation of translational elongation http://purl.obolibrary.org/obo/GO_0045901 GO:0045902 biolink:BiologicalProcess negative regulation of translational fidelity Any process that decreases the ability of the translational apparatus to interpret the genetic code. go-plus.json downregulation of translational fidelity|down regulation of translational fidelity|inhibition of translational fidelity|down-regulation of translational fidelity http://purl.obolibrary.org/obo/GO_0045902 GO:0045900 biolink:BiologicalProcess negative regulation of translational elongation Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. go-plus.json down-regulation of translational elongation|downregulation of translational elongation|down regulation of translational elongation|inhibition of translational elongation http://purl.obolibrary.org/obo/GO_0045900 GO:0045909 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045909 GO:0045907 biolink:BiologicalProcess positive regulation of vasoconstriction Any process that activates or increases the frequency, rate or extent of vasoconstriction. go-plus.json activation of vasoconstriction|up regulation of vasoconstriction|upregulation of vasoconstriction|stimulation of vasoconstriction|up-regulation of vasoconstriction http://purl.obolibrary.org/obo/GO_0045907 GO:0045908 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045908 GO:0006308 biolink:BiologicalProcess DNA catabolic process The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. go-plus.json DNA degradation|DNA catabolism|DNA breakdown http://purl.obolibrary.org/obo/GO_0006308 goslim_drosophila GO:0006309 biolink:BiologicalProcess apoptotic DNA fragmentation The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. go-plus.json DNA catabolic process during apoptosis|DNA catabolism during apoptosis|endonucleolytic DNA catabolic process involved in apoptosis|chromatinolysis|DNA fragmentation|DNA fragmentation involved in apoptotic nuclear change http://purl.obolibrary.org/obo/GO_0006309 GO:0006306 biolink:BiologicalProcess DNA methylation The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. Wikipedia:DNA_methylation go-plus.json http://purl.obolibrary.org/obo/GO_0006306 GO:0006307 biolink:BiologicalProcess DNA dealkylation involved in DNA repair The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT). go-plus.json http://purl.obolibrary.org/obo/GO_0006307 GO:0006304 biolink:BiologicalProcess DNA modification The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. go-plus.json http://purl.obolibrary.org/obo/GO_0006304 goslim_pir GO:0006305 biolink:BiologicalProcess DNA alkylation The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0006305 GO:0006302 biolink:BiologicalProcess double-strand break repair The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. go-plus.json http://purl.obolibrary.org/obo/GO_0006302 GO:0006303 biolink:BiologicalProcess double-strand break repair via nonhomologous end joining The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. go-plus.json NHEJ http://purl.obolibrary.org/obo/GO_0006303 GO:0021940 biolink:BiologicalProcess positive regulation of cerebellar granule cell precursor proliferation The process that activates or increases the rate or extent of granule cell precursor proliferation. go-plus.json upregulation of granule cell precursor proliferation|stimulation of granule cell precursor proliferation|up-regulation of granule cell precursor proliferation|activation of granule cell precursor proliferation|up regulation of granule cell precursor proliferation http://purl.obolibrary.org/obo/GO_0021940 GO:0006300 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006300 GO:0006301 biolink:BiologicalProcess postreplication repair The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication. Wikipedia:Postreplication_repair go-plus.json postreplication DNA repair http://purl.obolibrary.org/obo/GO_0006301 GO:0021949 biolink:BiologicalProcess brainstem precerebellar neuron precursor migration The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem. go-plus.json http://purl.obolibrary.org/obo/GO_0021949 GO:0021941 biolink:BiologicalProcess negative regulation of cerebellar granule cell precursor proliferation The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation. go-plus.json down regulation of granule cell precursor proliferation|inhibition of granule cell precursor proliferation|down-regulation of granule cell precursor proliferation|downregulation of granule cell precursor proliferation http://purl.obolibrary.org/obo/GO_0021941 GO:0021942 biolink:BiologicalProcess radial glia guided migration of Purkinje cell The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0021942 GO:0021943 biolink:BiologicalProcess formation of radial glial scaffolds The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells. go-plus.json Bergmann fiber biosynthesis|Bergmann fiber formation http://purl.obolibrary.org/obo/GO_0021943 GO:0021944 biolink:BiologicalProcess neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0021944 GO:0021945 biolink:BiologicalProcess positive regulation of cerebellar granule cell migration by calcium The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration. go-plus.json calcium-mediated up regulation of granule cell migration|calcium-mediated upregulation of granule cell migration|calcium-mediated stimulation of granule cell migration|calcium-mediated activation of granule cell migration|calcium-mediated up-regulation of granule cell migration|calcium-mediated positive regulation of granule cell migration http://purl.obolibrary.org/obo/GO_0021945 GO:0021946 biolink:BiologicalProcess deep nuclear neuron cell migration The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei. go-plus.json http://purl.obolibrary.org/obo/GO_0021946 GO:0021947 biolink:BiologicalProcess outward migration of deep nuclear neurons The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate. go-plus.json http://purl.obolibrary.org/obo/GO_0021947 GO:0021948 biolink:BiologicalProcess inward migration of deep nuclear neurons The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position. go-plus.json http://purl.obolibrary.org/obo/GO_0021948 GO:0006319 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006319 GO:0006317 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006317 GO:0006318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006318 CHEBI:46786 biolink:ChemicalSubstance diether go-plus.json http://purl.obolibrary.org/obo/CHEBI_46786 GO:0006315 biolink:BiologicalProcess homing of group II introns Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure. go-plus.json http://purl.obolibrary.org/obo/GO_0006315 CHEBI:46787 biolink:ChemicalSubstance solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_46787 GO:0006316 biolink:BiologicalProcess movement of group I intron Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0006316 GO:0006313 biolink:BiologicalProcess transposition, DNA-mediated Any process involved in a type of transpositional recombination which occurs via a DNA intermediate. go-plus.json Class II transposition|Tc1/mariner transposition|P-element transposition|P-element excision|DNA transposition|Tc3 transposition http://purl.obolibrary.org/obo/GO_0006313 GO:0006314 biolink:BiologicalProcess intron homing Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron. go-plus.json http://purl.obolibrary.org/obo/GO_0006314 GO:0006311 biolink:BiologicalProcess meiotic gene conversion The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele. go-plus.json gene conversion without reciprocal crossover http://purl.obolibrary.org/obo/GO_0006311 GO:0006312 biolink:BiologicalProcess mitotic recombination The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles. Wikipedia:Mitotic_crossover go-plus.json http://purl.obolibrary.org/obo/GO_0006312 GO:0006310 biolink:BiologicalProcess DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. go-plus.json http://purl.obolibrary.org/obo/GO_0006310 goslim_pombe|goslim_yeast|goslim_drosophila GO:0021938 biolink:BiologicalProcess smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells. go-plus.json hh signaling pathway involved in regulation of granule cell precursor cell proliferation|hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation|smoothened signalling pathway in regulation of granule cell precursor cell proliferation http://purl.obolibrary.org/obo/GO_0021938 GO:0021939 biolink:BiologicalProcess extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation. go-plus.json extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation http://purl.obolibrary.org/obo/GO_0021939 CHEBI:32154 biolink:ChemicalSubstance octadecan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_32154 chebi_ph7_3 CHEBI:4767 biolink:ChemicalSubstance Elastin go-plus.json http://purl.obolibrary.org/obo/CHEBI_4767 GO:0021930 biolink:BiologicalProcess cerebellar granule cell precursor proliferation The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021930 GO:0021931 biolink:BiologicalProcess rostral hindbrain neuronal precursor cell proliferation The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus. go-plus.json http://purl.obolibrary.org/obo/GO_0021931 GO:0021932 biolink:BiologicalProcess hindbrain radial glia guided cell migration The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021932 GO:0021933 biolink:BiologicalProcess radial glia guided migration of cerebellar granule cell The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0021933 GO:0021934 biolink:BiologicalProcess hindbrain tangential cell migration The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration. go-plus.json hindbrain neurophilic migration http://purl.obolibrary.org/obo/GO_0021934 GO:0021935 biolink:BiologicalProcess cerebellar granule cell precursor tangential migration The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium. go-plus.json http://purl.obolibrary.org/obo/GO_0021935 GO:0021936 biolink:BiologicalProcess regulation of cerebellar granule cell precursor proliferation The process that modulates the frequency, rate or extent of granule cell precursor proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0021936 GO:0021937 biolink:BiologicalProcess cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation. go-plus.json Purkinje cell-granule cell precursor cell signalling involved in regulation of granule cell precursor cell proliferation http://purl.obolibrary.org/obo/GO_0021937 CHEBI:46774 biolink:ChemicalSubstance polyether go-plus.json http://purl.obolibrary.org/obo/CHEBI_46774 CHEBI:46775 biolink:ChemicalSubstance N-alkylpyrrolidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46775 CHEBI:46770 biolink:ChemicalSubstance pyrrolidinecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46770 GO:0021927 biolink:BiologicalProcess deep nuclear neuron precursor proliferation The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0021927 GO:0021928 biolink:BiologicalProcess basket cell precursor proliferation The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021928 GO:0021929 biolink:BiologicalProcess stellate cell precursor proliferation The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021929 GO:0021920 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021920 GO:0021921 biolink:BiologicalProcess regulation of cell proliferation in dorsal spinal cord The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021921 GO:0021922 biolink:BiologicalProcess Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division. go-plus.json Wnt receptor signaling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt receptor signalling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt-activated signaling pathway involved in regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_0021922 GO:0021923 biolink:BiologicalProcess cell proliferation in hindbrain ventricular zone The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0021923 GO:0021924 biolink:BiologicalProcess cell proliferation in external granule layer The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere. go-plus.json http://purl.obolibrary.org/obo/GO_0021924 GO:0021925 biolink:BiologicalProcess cerebellar Purkinje cell precursor proliferation The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. go-plus.json http://purl.obolibrary.org/obo/GO_0021925 GO:0021926 biolink:BiologicalProcess Golgi cell precursor proliferation The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021926 CHEBI:46761 biolink:ChemicalSubstance dipeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_46761 CHEBI:46762 biolink:ChemicalSubstance (E,E,E)-geranylgeraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46762 chebi_ph7_3 CHEBI:46765 biolink:ChemicalSubstance carbapenem go-plus.json http://purl.obolibrary.org/obo/CHEBI_46765 chebi_ph7_3 CHEBI:46767 biolink:ChemicalSubstance pyrrolidinecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46767 CHEBI:4743 biolink:ChemicalSubstance ecgonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_4743 GO:0021916 biolink:BiologicalProcess inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis. go-plus.json inductive cell-cell signalling between paraxial mesoderm and motor neuron precursors http://purl.obolibrary.org/obo/GO_0021916 GO:0021917 biolink:BiologicalProcess somatic motor neuron fate commitment The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0021917 GO:0021918 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0021918 GO:0021919 biolink:BiologicalProcess BMP signaling pathway involved in spinal cord dorsal/ventral patterning A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord. go-plus.json bone morphogenetic protein signaling pathway in spinal cord dorsal-ventral patterning|BMP signaling pathway in spinal cord dorsoventral patterning|BMP signaling pathway involved in spinal cord dorsal-ventral patterning|BMP signalling pathway involved in spinal cord dorsal-ventral patterning|bone morphogenetic protein signalling pathway involved in spinal cord dorsal-ventral patterning http://purl.obolibrary.org/obo/GO_0021919 CHEBI:4746 biolink:ChemicalSubstance echinenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_4746 chebi_ph7_3 GO:0021910 biolink:BiologicalProcess smoothened signaling pathway involved in ventral spinal cord patterning The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord. go-plus.json hedgehog signaling pathway involved in ventral spinal cord patterning|hh signaling pathway involved in ventral spinal cord patterning|smoothened signalling pathway in ventral spinal cord patterning http://purl.obolibrary.org/obo/GO_0021910 GO:0021911 biolink:BiologicalProcess retinoic acid metabolic process in spinal cord anterior-posterior patterning The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. go-plus.json retinoic acid metabolism in spinal cord anterior-posterior patterning http://purl.obolibrary.org/obo/GO_0021911 GO:0021912 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021912 GO:0021913 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021913 GO:0021914 biolink:BiologicalProcess negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord. go-plus.json negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning|negative regulation of hh signaling pathway involved in ventral spinal cord patterning|down-regulation of smoothened signaling pathway in ventral spinal cord patterning|negative regulation of smoothened signalling pathway in ventral spinal cord patterning|downregulation of smoothened signaling pathway in ventral spinal cord patterning|down regulation of smoothened signaling pathway in ventral spinal cord patterning|inhibition of smoothened signaling pathway in ventral spinal cord patterning http://purl.obolibrary.org/obo/GO_0021914 GO:0021915 biolink:BiologicalProcess neural tube development The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0021915 CHEBI:22788 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22788 chebi_ph7_3 GO:0021905 biolink:BiologicalProcess forebrain-midbrain boundary formation The process whose specific outcome is the creation of the forebrain-midbrain boundary. go-plus.json http://purl.obolibrary.org/obo/GO_0021905 GO:0021906 biolink:BiologicalProcess hindbrain-spinal cord boundary formation The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. go-plus.json http://purl.obolibrary.org/obo/GO_0021906 GO:0021907 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. go-plus.json fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning http://purl.obolibrary.org/obo/GO_0021907 GO:0021908 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. go-plus.json retinoic acid receptor signalling pathway in spinal cord anterior-posterior patterning http://purl.obolibrary.org/obo/GO_0021908 GO:0021909 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021909 GO:0021900 biolink:BiologicalProcess ventricular zone cell fate commitment The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0021900 GO:0021901 biolink:BiologicalProcess early neuron fate commitment in forebrain The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021901 GO:0021902 biolink:BiologicalProcess commitment of neuronal cell to specific neuron type in forebrain The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021902 GO:0021903 biolink:BiologicalProcess rostrocaudal neural tube patterning The process in which the neural tube is divided into specific regions along the rostrocaudal axis. go-plus.json anterior-posterior neural tube patterning http://purl.obolibrary.org/obo/GO_0021903 GO:0021904 biolink:BiologicalProcess dorsal/ventral neural tube patterning The process in which the neural tube is regionalized in the dorsoventral axis. go-plus.json dorsoventral neural tube patterning|dorsal-ventral neural tube patterning http://purl.obolibrary.org/obo/GO_0021904 CHEBI:46740 biolink:ChemicalSubstance glycyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_46740 CHEBI:22798 biolink:ChemicalSubstance beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_22798 chebi_ph7_3 CHEBI:32115 biolink:ChemicalSubstance salvianin go-plus.json http://purl.obolibrary.org/obo/CHEBI_32115 CHEBI:46731 biolink:ChemicalSubstance alkyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46731 CHEBI:46733 biolink:ChemicalSubstance oxabicycloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46733 CHEBI:46734 biolink:ChemicalSubstance (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46734 chebi_ph7_3 OBO:GOREL_0000040 biolink:OntologyClass results_in GOREL:0000040 go-plus.json http://purl.obolibrary.org/obo/GOREL_0000040 CHEBI:116931 biolink:ChemicalSubstance nipecotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_116931 CHEBI:46738 biolink:ChemicalSubstance glycino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_46738 CHEBI:46722 biolink:ChemicalSubstance carbonate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_46722 CHEBI:46723 biolink:ChemicalSubstance phosphate mineral go-plus.json http://purl.obolibrary.org/obo/CHEBI_46723 CHEBI:22778 biolink:ChemicalSubstance beta-D-galactosyl groups go-plus.json http://purl.obolibrary.org/obo/CHEBI_22778 GO:0031469 biolink:CellularComponent polyhedral organelle An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy. go-plus.json BAC|bacterial microcompartment http://purl.obolibrary.org/obo/GO_0031469 goslim_pir GO:0031467 biolink:CellularComponent Cul7-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein. go-plus.json cullin-RING ligase 7|SCF7 complex|CRL7 complex|CDL7 complex http://purl.obolibrary.org/obo/GO_0031467 GO:0031468 biolink:BiologicalProcess nuclear membrane reassembly The reformation of the nuclear membranes following their breakdown in the context of a normal process. go-plus.json nuclear envelope reassembly http://purl.obolibrary.org/obo/GO_0031468 GO:0031465 biolink:CellularComponent Cul4B-RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits. go-plus.json cullin-RING ligase 4B http://purl.obolibrary.org/obo/GO_0031465 GO:0031466 biolink:CellularComponent Cul5-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. go-plus.json CDL5 complex|cullin-RING ligase 5|SCF5 complex|CRL5 complex|EC2S complex http://purl.obolibrary.org/obo/GO_0031466 CHEBI:4593 biolink:ChemicalSubstance dihydroxyfumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4593 GO:0031463 biolink:CellularComponent Cul3-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein. go-plus.json CDL3 complex|cullin-RING ligase 3|BCR3 complex|SCF3 complex|CRL3 complex|BC3B complex http://purl.obolibrary.org/obo/GO_0031463 GO:0031464 biolink:CellularComponent Cul4A-RING E3 ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. go-plus.json CDL4 complex|VDC complex|cullin-RING ligase 4A|SCF4 complex|DCX complex|CRL4 complex http://purl.obolibrary.org/obo/GO_0031464 GO:0031461 biolink:CellularComponent cullin-RING ubiquitin ligase complex Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity. go-plus.json CRL complex|cullin complex|cullin-RING ligase http://purl.obolibrary.org/obo/GO_0031461 GO:0031462 biolink:CellularComponent Cul2-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. go-plus.json CDL2 complex|cullin-RING ligase 2|VBC complex|CBC complex|SCF2 complex|CRL2 complex|EC2S complex|ECS complex http://purl.obolibrary.org/obo/GO_0031462 GO:0031460 biolink:BiologicalProcess glycine betaine transport The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json N-trimethylglycine transport http://purl.obolibrary.org/obo/GO_0031460 GO:0031458 biolink:MolecularActivity ABC-type betaine transporter activity Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in). go-plus.json betaine ABC transporter|ABC-type betaine transmembrane transporter activity|ATP-dependent betaine transporter activity|ATPase-coupled betaine transporter activity|betaine-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0031458 GO:0031459 biolink:MolecularActivity ABC-type glycine betaine transporter activity Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in). RHEA:32783 go-plus.json ATP-dependent glycine betaine transporter activity|ATPase-coupled glycine betaine transporter activity|glycine betaine ABC transporter|glycine betaine-transporting ATPase activity|N-trimethylglycine-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0031459 GO:0031456 biolink:BiologicalProcess glycine betaine biosynthetic process The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine. go-plus.json glycine betaine biosynthesis|N-trimethylglycine biosynthetic process|N-trimethylglycine biosynthesis|glycine betaine anabolism|glycine betaine synthesis|glycine betaine formation http://purl.obolibrary.org/obo/GO_0031456 GO:0031457 biolink:BiologicalProcess glycine betaine catabolic process The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine. go-plus.json N-trimethylglycine catabolism|glycine betaine degradation|N-trimethylglycine catabolic process|glycine betaine breakdown|glycine betaine catabolism http://purl.obolibrary.org/obo/GO_0031457 CHEBI:141997 biolink:ChemicalSubstance hydroxy-L-argininium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_141997 chebi_ph7_3 GO:0031454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031454 GO:0031455 biolink:BiologicalProcess glycine betaine metabolic process The chemical reactions and pathways involving glycine betaine, N-trimethylglycine. go-plus.json N-trimethylglycine metabolic process|glycine betaine metabolism|N-trimethylglycine metabolism http://purl.obolibrary.org/obo/GO_0031455 GO:0031452 biolink:BiologicalProcess negative regulation of heterochromatin assembly Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. go-plus.json inhibition of heterochromatin formation|down regulation of heterochromatin formation|downregulation of heterochromatin formation|negative regulation of heterochromatin formation|down-regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0031452 GO:0031453 biolink:BiologicalProcess positive regulation of heterochromatin assembly Any process that activates or increases the frequency, rate or extent of heterochromatin formation. go-plus.json up-regulation of heterochromatin formation|upregulation of heterochromatin formation|up regulation of heterochromatin formation|activation of heterochromatin formation|positive regulation of heterochromatin formation|stimulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0031453 GO:0031450 biolink:BiologicalProcess negative regulation of slow-twitch skeletal muscle fiber contraction Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction. go-plus.json inhibition of slow-twitch skeletal muscle contraction|down regulation of slow-twitch skeletal muscle contraction|negative regulation of slow-twitch skeletal muscle contraction|downregulation of slow-twitch skeletal muscle contraction|down-regulation of slow-twitch skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0031450 GO:0031451 biolink:BiologicalProcess positive regulation of slow-twitch skeletal muscle fiber contraction Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction. go-plus.json up-regulation of slow-twitch skeletal muscle contraction|upregulation of slow-twitch skeletal muscle contraction|positive regulation of slow-twitch skeletal muscle contraction|up regulation of slow-twitch skeletal muscle contraction|activation of slow-twitch skeletal muscle contraction|stimulation of slow-twitch skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0031451 GO:0031449 biolink:BiologicalProcess regulation of slow-twitch skeletal muscle fiber contraction Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction. go-plus.json regulation of slow-twitch skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0031449 GO:0031447 biolink:BiologicalProcess negative regulation of fast-twitch skeletal muscle fiber contraction Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction. go-plus.json downregulation of fast-twitch skeletal muscle contraction|down-regulation of fast-twitch skeletal muscle contraction|inhibition of fast-twitch skeletal muscle contraction|down regulation of fast-twitch skeletal muscle contraction|negative regulation of fast-twitch skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0031447 GO:0031448 biolink:BiologicalProcess positive regulation of fast-twitch skeletal muscle fiber contraction Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction. go-plus.json up regulation of fast-twitch skeletal muscle contraction|activation of fast-twitch skeletal muscle contraction|stimulation of fast-twitch skeletal muscle contraction|up-regulation of fast-twitch skeletal muscle contraction|upregulation of fast-twitch skeletal muscle contraction|positive regulation of fast-twitch skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0031448 GO:0006489 biolink:BiologicalProcess dolichyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative. go-plus.json dolichyl diphosphate biosynthesis|dolichyl diphosphate anabolism|dolichyl diphosphate synthesis|dolichyl diphosphate formation http://purl.obolibrary.org/obo/GO_0006489 GO:0031445 biolink:BiologicalProcess regulation of heterochromatin assembly Any process that modulates the frequency, rate, extent or location of heterochromatin formation. go-plus.json regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0031445 GO:0031446 biolink:BiologicalProcess regulation of fast-twitch skeletal muscle fiber contraction Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction. go-plus.json regulation of fast-twitch skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0031446 GO:0006487 biolink:BiologicalProcess protein N-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. RESID:AA0327|RESID:AA0156|RESID:AA0151 go-plus.json N-glycan biosynthesis|N-glycan metabolism|protein amino acid N-linked glycosylation http://purl.obolibrary.org/obo/GO_0006487 GO:0006488 biolink:BiologicalProcess dolichol-linked oligosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P. go-plus.json oligosaccharide-PP-dolichol assembly|dolichol-linked oligosaccharide anabolism|dolichol-linked oligosaccharide synthesis|dolichol-linked oligosaccharide formation|dolichol-linked oligosaccharide biosynthesis|N-linked glycan precursor biosynthesis|N-linked glycan precursor biosynthetic process http://purl.obolibrary.org/obo/GO_0006488 GO:0006485 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006485 GO:0006486 biolink:BiologicalProcess protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. go-plus.json protein amino acid glycosylation|protein-carbohydrate complex assembly http://purl.obolibrary.org/obo/GO_0006486 goslim_yeast|goslim_pombe GO:0006483 biolink:BiologicalProcess obsolete peptidyl-aspartic acid/asparagine hydroxylation OBSOLETE. The hydroxylation of peptidyl-aspartic acid or asparagine. go-plus.json peptidyl-aspartic acid/asparagine hydroxylation|aspartic acid/asparagine hydroxylation http://purl.obolibrary.org/obo/GO_0006483 GO:0006484 biolink:BiologicalProcess obsolete protein cysteine-thiol oxidation OBSOLETE. Oxidation of two cysteine sulfhydryl groups (thiols) in one protein by a disulfide bond in a second protein to form a disulfide bond in the first protein and two reduced sulfhydryls in the second. The oxidized cysteines linked by a disulfide bond is known as cystine. go-plus.json protein cysteine-thiol oxidation http://purl.obolibrary.org/obo/GO_0006484 GO:0006481 biolink:BiologicalProcess C-terminal protein methylation The methylation of the C-terminal amino acid of a protein. go-plus.json C-terminal protein amino acid methylation http://purl.obolibrary.org/obo/GO_0006481 GO:0006482 biolink:BiologicalProcess protein demethylation The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. go-plus.json protein amino acid demethylation http://purl.obolibrary.org/obo/GO_0006482 GO:0006490 biolink:BiologicalProcess oligosaccharide-lipid intermediate biosynthetic process The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation. go-plus.json oligosaccharide-lipid intermediate biosynthetic process|oligosaccharide-lipid intermediate assembly http://purl.obolibrary.org/obo/GO_0006490 CHEBI:4579 biolink:ChemicalSubstance dihydropinosylvin go-plus.json http://purl.obolibrary.org/obo/CHEBI_4579 chebi_ph7_3 GO:0006491 biolink:BiologicalProcess N-glycan processing The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking. go-plus.json glycoprotein trimming involved in glycoprotein maturation|N-linked glycoprotein maturation http://purl.obolibrary.org/obo/GO_0006491 GO:0031443 biolink:BiologicalProcess fast-twitch skeletal muscle fiber contraction A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability. go-plus.json fast-twitch skeletal fibre contraction|fast-twitch skeletal fiber contraction|fast-twitch skeletal myofibre contraction|fast-twitch skeletal myofiber contraction|fast-twitch skeletal muscle fibre contraction http://purl.obolibrary.org/obo/GO_0031443 GO:0031444 biolink:BiologicalProcess slow-twitch skeletal muscle fiber contraction A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue. go-plus.json slow-twitch skeletal muscle fibre contraction http://purl.obolibrary.org/obo/GO_0031444 GO:0031441 biolink:BiologicalProcess negative regulation of mRNA 3'-end processing Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing. go-plus.json down regulation of mRNA 3'-end processing|inhibition of mRNA 3'-end processing|down-regulation of mRNA 3'-end processing|downregulation of mRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0031441 GO:0031442 biolink:BiologicalProcess positive regulation of mRNA 3'-end processing Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing. go-plus.json upregulation of mRNA 3'-end processing|stimulation of mRNA 3'-end processing|up-regulation of mRNA 3'-end processing|activation of mRNA 3'-end processing|up regulation of mRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0031442 GO:0031440 biolink:BiologicalProcess regulation of mRNA 3'-end processing Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0031440 GO:0031438 biolink:BiologicalProcess negative regulation of mRNA cleavage Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage. go-plus.json down regulation of mRNA cleavage|downregulation of mRNA cleavage|down-regulation of mRNA cleavage|inhibition of mRNA cleavage http://purl.obolibrary.org/obo/GO_0031438 GO:0031439 biolink:BiologicalProcess positive regulation of mRNA cleavage Any process that activates or increases the frequency, rate or extent of mRNA cleavage. go-plus.json up-regulation of mRNA cleavage|upregulation of mRNA cleavage|up regulation of mRNA cleavage|activation of mRNA cleavage|stimulation of mRNA cleavage http://purl.obolibrary.org/obo/GO_0031439 GO:0031436 biolink:CellularComponent BRCA1-BARD1 complex A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_0031436 GO:0031437 biolink:BiologicalProcess regulation of mRNA cleavage Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. go-plus.json http://purl.obolibrary.org/obo/GO_0031437 GO:0031434 biolink:MolecularActivity mitogen-activated protein kinase kinase binding Binding to a mitogen-activated protein kinase kinase, a protein that can phosphorylate a MAP kinase. go-plus.json MAPKK binding http://purl.obolibrary.org/obo/GO_0031434 GO:0031435 biolink:MolecularActivity mitogen-activated protein kinase kinase kinase binding Binding to a mitogen-activated protein kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase. go-plus.json MAPKKK binding http://purl.obolibrary.org/obo/GO_0031435 GO:0006498 biolink:BiologicalProcess N-terminal protein lipidation The covalent attachment of a lipid group to the amino terminus of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0006498 CHEBI:356445 biolink:ChemicalSubstance glycylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_356445 chebi_ph7_3 GO:0006499 biolink:BiologicalProcess N-terminal protein myristoylation The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0006499 GO:0006496 biolink:BiologicalProcess obsolete protein amino acid terminal N-glycosylation OBSOLETE. The glycosylation of a nitrogen atom of a free alpha amino terminal of a peptide. go-plus.json protein amino acid terminal N-glycosylation http://purl.obolibrary.org/obo/GO_0006496 GO:0006497 biolink:BiologicalProcess protein lipidation The covalent attachment of lipid groups to an amino acid in a protein. RESID:AA0077|RESID:AA0163|RESID:AA0162|RESID:AA0161|RESID:AA0160|RESID:AA0060|RESID:AA0290|RESID:AA0080|RESID:AA0309|RESID:AA0308|RESID:AA0307|RESID:AA0107|RESID:AA0316|RESID:AA0106|RESID:AA0104|RESID:AA0159|RESID:AA0059|RESID:AA0103|RESID:AA0158|RESID:AA0223|RESID:AA0102|RESID:AA0079|RESID:AA0078|RESID:AA0166 go-plus.json protein amino acid lipidation|lipid:protein modification http://purl.obolibrary.org/obo/GO_0006497 goslim_yeast|goslim_drosophila GO:0006494 biolink:BiologicalProcess obsolete protein amino acid terminal glycosylation OBSOLETE. A protein amino acid glycosylation process in which a sugar unit is added to a free alpha-amino or alpha-carboxyl terminal of a peptide. go-plus.json protein amino acid terminal glycosylation http://purl.obolibrary.org/obo/GO_0006494 GO:0006495 biolink:BiologicalProcess obsolete terminal O-glycosylation OBSOLETE. (Was not defined before being made obsolete). go-plus.json terminal O-glycosylation http://purl.obolibrary.org/obo/GO_0006495 GO:0006492 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006492 GO:0006493 biolink:BiologicalProcess protein O-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan. RESID:AA0212|RESID:AA0157|RESID:AA0155|RESID:AA0154|RESID:AA0153 go-plus.json protein amino acid O-linked glycosylation http://purl.obolibrary.org/obo/GO_0006493 CHEBI:4581 biolink:ChemicalSubstance 7,8-dihydropteroic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4581 GO:0031432 biolink:MolecularActivity titin binding Binding to titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0031432 GO:0031433 biolink:MolecularActivity telethonin binding Binding to telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0031433 GO:0031430 biolink:CellularComponent M band The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines. Wikipedia:Sarcomere#bands go-plus.json M line|M disc|mesophragma|midline http://purl.obolibrary.org/obo/GO_0031430 GO:0031431 biolink:CellularComponent Dbf4-dependent protein kinase complex A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins. go-plus.json DDK|Cdc7-Dbf4 complex|Hsk1-Dfp1 kinase complex http://purl.obolibrary.org/obo/GO_0031431 CHEBI:32096 biolink:ChemicalSubstance rhodomycin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_32096 GO:0031429 biolink:CellularComponent box H/ACA snoRNP complex A box H/ACA RNP complex that is located in the nucleolus. go-plus.json box H/ACA small nucleolar ribonucleoprotein complex|box H/ACA snoRNP pseudouridylase complex http://purl.obolibrary.org/obo/GO_0031429 GO:0031427 biolink:BiologicalProcess response to methotrexate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. go-plus.json http://purl.obolibrary.org/obo/GO_0031427 GO:0031428 biolink:CellularComponent box C/D RNP complex A ribonucleoprotein complex containing a box C/D type RNA that can carry out ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya. go-plus.json box C/D snoRNP ribose-2'-O-methyltransferase complex|box C/D small nucleolar ribonucleoprotein complex|box C/D snoRNP complex|box C/D snoRNP ribose 2'-O methylase complex|box C/D sRNP complex http://purl.obolibrary.org/obo/GO_0031428 GO:0031425 biolink:BiologicalProcess chloroplast RNA processing The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0031425 GO:0006469 biolink:BiologicalProcess negative regulation of protein kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. go-plus.json down-regulation of protein kinase activity|inhibition of protein kinase activity|down regulation of protein kinase activity|downregulation of protein kinase activity http://purl.obolibrary.org/obo/GO_0006469 GO:0031426 biolink:BiologicalProcess polycistronic mRNA processing The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0031426 GO:0031423 biolink:MolecularActivity hexon binding Binding to a hexon, the major protein component of the icosahedral capsid of an adenovirus. go-plus.json http://purl.obolibrary.org/obo/GO_0031423 GO:0006467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006467 GO:0006468 biolink:BiologicalProcess protein phosphorylation The process of introducing a phosphate group on to a protein. go-plus.json protein amino acid phosphorylation http://purl.obolibrary.org/obo/GO_0006468 goslim_yeast GO:0031424 biolink:BiologicalProcess keratinization The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. go-plus.json http://purl.obolibrary.org/obo/GO_0031424 GO:0006465 biolink:BiologicalProcess signal peptide processing The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell. go-plus.json leader peptide processing http://purl.obolibrary.org/obo/GO_0006465 GO:0006466 biolink:BiologicalProcess obsolete protein disulfide-isomerase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json protein disulphide-isomerase reaction|protein disulfide-isomerase reaction http://purl.obolibrary.org/obo/GO_0006466 GO:0006463 biolink:BiologicalProcess steroid hormone receptor complex assembly The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0006463 GO:0006464 biolink:BiologicalProcess cellular protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). go-plus.json protein tagging activity|process resulting in protein modification|protein modification process http://purl.obolibrary.org/obo/GO_0006464 goslim_chembl|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_generic GO:0006461 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006461 GO:0006462 biolink:BiologicalProcess obsolete protein complex assembly, multichaperone pathway OBSOLETE. (Was not defined before being made obsolete). go-plus.json protein complex assembly, multichaperone pathway http://purl.obolibrary.org/obo/GO_0006462 GO:0006460 biolink:BiologicalProcess obsolete peptidyl-prolyl isomerase B reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json peptidyl-prolyl isomerase B reaction http://purl.obolibrary.org/obo/GO_0006460 GO:0031421 biolink:CellularComponent invertasome A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts. go-plus.json http://purl.obolibrary.org/obo/GO_0031421 GO:0031422 biolink:CellularComponent RecQ family helicase-topoisomerase III complex A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human. go-plus.json Sgs1-Top3 complex|RecQ helicase-Topo III complex http://purl.obolibrary.org/obo/GO_0031422 GO:0031420 biolink:MolecularActivity alkali metal ion binding Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0031420 GO:0031418 biolink:MolecularActivity L-ascorbic acid binding Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. go-plus.json L-ascorbate binding|vitamin C binding http://purl.obolibrary.org/obo/GO_0031418 GO:0031419 biolink:MolecularActivity cobalamin binding Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. go-plus.json vitamin B12 binding http://purl.obolibrary.org/obo/GO_0031419 GO:0031416 biolink:CellularComponent NatB complex A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p. go-plus.json N-terminal acetyltransferase B complex http://purl.obolibrary.org/obo/GO_0031416 GO:0031417 biolink:CellularComponent NatC complex A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p. go-plus.json N-terminal acetyltransferase C complex http://purl.obolibrary.org/obo/GO_0031417 GO:0031414 biolink:CellularComponent N-terminal protein acetyltransferase complex A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule. go-plus.json NAT complex http://purl.obolibrary.org/obo/GO_0031414 GO:0031415 biolink:CellularComponent NatA complex A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins. go-plus.json N-terminal acetyltransferase A complex http://purl.obolibrary.org/obo/GO_0031415 GO:0006478 biolink:BiologicalProcess peptidyl-tyrosine sulfation The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine. RESID:AA0172 go-plus.json peptidyl-tyrosine sulphation http://purl.obolibrary.org/obo/GO_0006478 GO:0031412 biolink:BiologicalProcess gas vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. go-plus.json gas vesicle organisation|gas vesicle formation|gas vesicle organization and biogenesis|gas vesicle biosynthesis http://purl.obolibrary.org/obo/GO_0031412 GO:0031413 biolink:BiologicalProcess regulation of buoyancy Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases. go-plus.json buoyancy regulation http://purl.obolibrary.org/obo/GO_0031413 GO:0006479 biolink:BiologicalProcess protein methylation The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. go-plus.json protein amino acid methylation http://purl.obolibrary.org/obo/GO_0006479 GO:0006476 biolink:BiologicalProcess protein deacetylation The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json protein amino acid deacetylation http://purl.obolibrary.org/obo/GO_0006476 GO:0006477 biolink:BiologicalProcess protein sulfation The addition of a sulfate group as an ester to a protein amino acid. go-plus.json protein amino acid sulfation|protein amino acid sulphation http://purl.obolibrary.org/obo/GO_0006477 GO:0006474 biolink:BiologicalProcess N-terminal protein amino acid acetylation The acetylation of the N-terminal amino acid of proteins. go-plus.json N(alpha)-terminal acetylation http://purl.obolibrary.org/obo/GO_0006474 GO:0006475 biolink:BiologicalProcess internal protein amino acid acetylation The addition of an acetyl group to a non-terminal amino acid in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0006475 GO:0006472 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006472 GO:0006473 biolink:BiologicalProcess protein acetylation The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json protein amino acid acetylation http://purl.obolibrary.org/obo/GO_0006473 GO:0006470 biolink:BiologicalProcess protein dephosphorylation The process of removing one or more phosphoric residues from a protein. go-plus.json protein amino acid dephosphorylation http://purl.obolibrary.org/obo/GO_0006470 goslim_yeast GO:0006471 biolink:BiologicalProcess protein ADP-ribosylation The transfer, from NAD, of ADP-ribose to protein amino acids. RESID:AA0231|RESID:AA0295|RESID:AA0040|RESID:AA0237|RESID:AA0169|RESID:AA0168 go-plus.json protein amino acid ADP-ribosylation http://purl.obolibrary.org/obo/GO_0006471 GO:0006480 biolink:BiologicalProcess N-terminal protein amino acid methylation The methylation of the N-terminal amino acid of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0006480 CHEBI:32079 biolink:ChemicalSubstance pyrrolnitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_32079 chebi_ph7_3 GO:0031410 biolink:CellularComponent cytoplasmic vesicle A vesicle found in the cytoplasm of a cell. NIF_Subcellular:sao180601769 go-plus.json cytoplasmic, membrane-bounded vesicle|cytoplasmic membrane-enclosed vesicle|cytoplasmic membrane bounded vesicle http://purl.obolibrary.org/obo/GO_0031410 goslim_candida|goslim_agr|goslim_yeast|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_mouse GO:0031411 biolink:CellularComponent gas vesicle An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations. go-plus.json gas vacuole http://purl.obolibrary.org/obo/GO_0031411 CHEBI:46695 biolink:ChemicalSubstance fluorohydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_46695 GO:0031407 biolink:BiologicalProcess oxylipin metabolic process The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids. go-plus.json oxylipin metabolism http://purl.obolibrary.org/obo/GO_0031407 GO:0031408 biolink:BiologicalProcess oxylipin biosynthetic process The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids. go-plus.json oxylipin biosynthesis|oxylipin anabolism|oxylipin synthesis|oxylipin formation http://purl.obolibrary.org/obo/GO_0031408 GO:0006449 biolink:BiologicalProcess regulation of translational termination Any process that modulates the frequency, rate or extent of translational termination. go-plus.json http://purl.obolibrary.org/obo/GO_0006449 GO:0031405 biolink:MolecularActivity lipoic acid binding Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0031405 GO:0031406 biolink:MolecularActivity carboxylic acid binding Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-). go-plus.json http://purl.obolibrary.org/obo/GO_0031406 goslim_pir GO:0031403 biolink:MolecularActivity lithium ion binding Binding to a lithium ion (Li+). go-plus.json Li+ ion binding http://purl.obolibrary.org/obo/GO_0031403 GO:0006447 biolink:BiologicalProcess regulation of translational initiation by iron Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron. go-plus.json http://purl.obolibrary.org/obo/GO_0006447 GO:0031404 biolink:MolecularActivity chloride ion binding Binding to a chloride ion (Cl-). go-plus.json chloride binding|Cl- ion binding http://purl.obolibrary.org/obo/GO_0031404 GO:0006448 biolink:BiologicalProcess regulation of translational elongation Any process that modulates the frequency, rate, extent or accuracy of translational elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0006448 GO:0006445 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006445 GO:0031401 biolink:BiologicalProcess positive regulation of protein modification process Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. go-plus.json stimulation of protein modification|up-regulation of protein modification|activation of protein modification|up regulation of protein modification|upregulation of protein modification http://purl.obolibrary.org/obo/GO_0031401 GO:0031402 biolink:MolecularActivity sodium ion binding Binding to a sodium ion (Na+). go-plus.json Na+ ion binding http://purl.obolibrary.org/obo/GO_0031402 GO:0006446 biolink:BiologicalProcess regulation of translational initiation Any process that modulates the frequency, rate or extent of translational initiation. go-plus.json http://purl.obolibrary.org/obo/GO_0006446 GO:0006443 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006443 GO:0006444 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006444 GO:0006441 biolink:BiologicalProcess obsolete binding to mRNA cap OBSOLETE. (Was not defined before being made obsolete). go-plus.json binding to mRNA cap http://purl.obolibrary.org/obo/GO_0006441 GO:0006442 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006442 CHEBI:46691 biolink:ChemicalSubstance 2,3-dihydroxy-5-methyl-1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_46691 GO:0006440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006440 GO:0031409 biolink:MolecularActivity pigment binding Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin. go-plus.json http://purl.obolibrary.org/obo/GO_0031409 goslim_pir OBO:GOCHE_23357 biolink:OntologyClass substance with cofactor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_23357 3_STAR GO:0031400 biolink:BiologicalProcess negative regulation of protein modification process Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. go-plus.json down-regulation of protein modification|downregulation of protein modification|down regulation of protein modification|inhibition of protein modification http://purl.obolibrary.org/obo/GO_0031400 CHEBI:46685 biolink:ChemicalSubstance oxadiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_46685 CHEBI:46686 biolink:ChemicalSubstance azaalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46686 CHEBI:46687 biolink:ChemicalSubstance diazaalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46687 GO:0006458 biolink:BiologicalProcess 'de novo' protein folding The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure. go-plus.json nascent chain protein folding http://purl.obolibrary.org/obo/GO_0006458 GO:0006459 biolink:BiologicalProcess obsolete binding unfolded ER proteins OBSOLETE. (Was not defined before being made obsolete). go-plus.json binding unfolded ER proteins http://purl.obolibrary.org/obo/GO_0006459 GO:0006456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006456 GO:0006457 biolink:BiologicalProcess protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. Wikipedia:Protein_folding go-plus.json co-chaperone activity|chaperone activity|co-chaperonin activity|beta-tubulin folding|chaperonin ATPase activity|protein complex assembly, multichaperone pathway|chaperonin-mediated tubulin folding|alpha-tubulin folding|non-chaperonin molecular chaperone ATPase activity|glycoprotein-specific chaperone activity http://purl.obolibrary.org/obo/GO_0006457 goslim_pir|goslim_drosophila|goslim_metagenomics|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast|goslim_candida GO:0006454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006454 GO:0006455 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006455 GO:0006452 biolink:BiologicalProcess translational frameshifting A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon. Wikipedia:Translational_frameshift go-plus.json http://purl.obolibrary.org/obo/GO_0006452 GO:0006453 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006453 GO:0006450 biolink:BiologicalProcess regulation of translational fidelity Any process that modulates the ability of the translational apparatus to interpret the genetic code. go-plus.json regulation of translational accuracy http://purl.obolibrary.org/obo/GO_0006450 GO:0006451 biolink:BiologicalProcess translational readthrough The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons. go-plus.json natural nonsense suppression http://purl.obolibrary.org/obo/GO_0006451 CHEBI:71632 biolink:ChemicalSubstance pyrazine N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71632 CHEBI:71633 biolink:ChemicalSubstance hydroxypyrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71633 CHEBI:71634 biolink:ChemicalSubstance hydroxyversicolorone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71634 CHEBI:71635 biolink:ChemicalSubstance versicolorone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71635 chebi_ph7_3 CHEBI:71636 biolink:ChemicalSubstance versiconol acetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71636 chebi_ph7_3 CHEBI:71637 biolink:ChemicalSubstance versiconal hemiacetal acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71637 CHEBI:71638 biolink:ChemicalSubstance versiconal hemiacetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_71638 CHEBI:71639 biolink:ChemicalSubstance versiconol go-plus.json http://purl.obolibrary.org/obo/CHEBI_71639 CHEBI:71648 biolink:ChemicalSubstance hydroxybenzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71648 CHEBI:71649 biolink:ChemicalSubstance (S)-5'-oxoaverantin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71649 CHEBI:71652 biolink:ChemicalSubstance anthrafuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_71652 CHEBI:71653 biolink:ChemicalSubstance versicolorone tricyclic form go-plus.json http://purl.obolibrary.org/obo/CHEBI_71653 CHEBI:71654 biolink:ChemicalSubstance versicolorone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71654 CHEBI:71657 biolink:ChemicalSubstance versiconol acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71657 CHEBI:71662 biolink:ChemicalSubstance versiconal go-plus.json http://purl.obolibrary.org/obo/CHEBI_71662 CHEBI:71665 biolink:ChemicalSubstance (S)-versiconol go-plus.json http://purl.obolibrary.org/obo/CHEBI_71665 CHEBI:71666 biolink:ChemicalSubstance gamma-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71666 CHEBI:71661 biolink:ChemicalSubstance anthocyanidin 3-glucoside 5-[(6-O-4-hydroxycinnamoyl)glucoside] go-plus.json http://purl.obolibrary.org/obo/CHEBI_71661 CHEBI:71673 biolink:ChemicalSubstance N-acetyl-D-galactosamine 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71673 chebi_ph7_3 CHEBI:71674 biolink:ChemicalSubstance D-galactosamine 6-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71674 chebi_ph7_3 CHEBI:71677 biolink:ChemicalSubstance (2S)-2-hydroxy-3,4-diketopentyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71677 chebi_ph7_3 CHEBI:71678 biolink:ChemicalSubstance N(6)-(dimethylallyl)adenosine 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71678 CHEBI:71679 biolink:ChemicalSubstance N(6)-(dimethylallyl)adenosine 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71679 CHEBI:71670 biolink:ChemicalSubstance N-acetyl-L-methionine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71670 chebi_ph7_3 CHEBI:71671 biolink:ChemicalSubstance aldonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71671 chebi_ph7_3 CHEBI:71684 biolink:ChemicalSubstance (2S)-2-hydroxy-3,4-diketopentyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71684 CHEBI:71685 biolink:ChemicalSubstance L-4-hydroxy-2-oxoglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71685 chebi_ph7_3 CHEBI:71688 biolink:ChemicalSubstance 7-epi-zingiberene go-plus.json http://purl.obolibrary.org/obo/CHEBI_71688 chebi_ph7_3 CHEBI:71689 biolink:ChemicalSubstance L-4-hydroxy-2-oxoglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71689 GO:0031490 biolink:MolecularActivity chromatin DNA binding Binding to DNA that is assembled into chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0031490 GO:0031491 biolink:MolecularActivity nucleosome binding Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. go-plus.json http://purl.obolibrary.org/obo/GO_0031491 GO:0031498 biolink:BiologicalProcess chromatin disassembly The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA. go-plus.json chromatin maintenance http://purl.obolibrary.org/obo/GO_0031498 GO:0031499 biolink:CellularComponent TRAMP complex A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control. Wikipedia:TRAMP_complex go-plus.json TRAMP5 complex|TRAMP4 complex|Trf4 complex|Trf4p-Air2p-Mtr4p polyadenylation complex|Trf4 poly(A) polymerase complex http://purl.obolibrary.org/obo/GO_0031499 GO:0031496 biolink:BiologicalProcess positive regulation of mating type switching Any process that activates or increases the frequency, rate or extent of mating type switching. go-plus.json up-regulation of mating type switching|upregulation of mating type switching|up regulation of mating type switching|activation of mating type switching|stimulation of mating type switching http://purl.obolibrary.org/obo/GO_0031496 GO:0031497 biolink:BiologicalProcess chromatin assembly The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. go-plus.json establishment of chromatin architecture|chromatin maintenance http://purl.obolibrary.org/obo/GO_0031497 GO:0031494 biolink:BiologicalProcess regulation of mating type switching Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus. go-plus.json http://purl.obolibrary.org/obo/GO_0031494 GO:0031495 biolink:BiologicalProcess negative regulation of mating type switching Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching. go-plus.json inhibition of mating type switching|down regulation of mating type switching|downregulation of mating type switching|down-regulation of mating type switching http://purl.obolibrary.org/obo/GO_0031495 CHEBI:71681 biolink:ChemicalSubstance D-gamma-glutamyl-D-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71681 chebi_ph7_3 GO:0031492 biolink:MolecularActivity nucleosomal DNA binding Binding to the DNA portion of a nucleosome. go-plus.json http://purl.obolibrary.org/obo/GO_0031492 CHEBI:71682 biolink:ChemicalSubstance cyanidin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71682 chebi_ph7_3 CHEBI:71683 biolink:ChemicalSubstance D-gamma-glutamyl-D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71683 GO:0031493 biolink:MolecularActivity nucleosomal histone binding Binding to a histone that is assembled into a nucleosome. go-plus.json http://purl.obolibrary.org/obo/GO_0031493 GO:0031489 biolink:MolecularActivity myosin V binding Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport. go-plus.json http://purl.obolibrary.org/obo/GO_0031489 CHEBI:81014 biolink:ChemicalSubstance 3beta-hydroxycholest-5-en-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81014 CHEBI:81013 biolink:ChemicalSubstance 7alpha,25-dihydroxy-4-cholesten-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_81013 chebi_ph7_3 GO:0031480 biolink:CellularComponent myosin X complex A myosin complex containing one or more class X myosin heavy chains and associated light chains. go-plus.json http://purl.obolibrary.org/obo/GO_0031480 GO:0031487 biolink:CellularComponent myosin XVII complex A myosin complex containing one or more class XVII myosin heavy chains and associated light chains. go-plus.json http://purl.obolibrary.org/obo/GO_0031487 GO:0031488 biolink:CellularComponent myosin XVIII complex A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain. go-plus.json http://purl.obolibrary.org/obo/GO_0031488 GO:0031485 biolink:CellularComponent myosin XV complex A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII. go-plus.json http://purl.obolibrary.org/obo/GO_0031485 GO:0031486 biolink:CellularComponent myosin XVI complex A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat. go-plus.json http://purl.obolibrary.org/obo/GO_0031486 GO:0031483 biolink:CellularComponent myosin XIII complex A myosin complex containing one or more class XIII myosin heavy chains and associated light chains. go-plus.json http://purl.obolibrary.org/obo/GO_0031483 GO:0031484 biolink:CellularComponent myosin XIV complex A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails. go-plus.json http://purl.obolibrary.org/obo/GO_0031484 CHEBI:71692 biolink:ChemicalSubstance insect repellent go-plus.json http://purl.obolibrary.org/obo/CHEBI_71692 GO:0031481 biolink:CellularComponent myosin XI complex A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions. go-plus.json http://purl.obolibrary.org/obo/GO_0031481 GO:0031482 biolink:CellularComponent myosin XII complex A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil. go-plus.json http://purl.obolibrary.org/obo/GO_0031482 GO:0031478 biolink:CellularComponent myosin VIII complex A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain. go-plus.json http://purl.obolibrary.org/obo/GO_0031478 GO:0031479 biolink:CellularComponent myosin IX complex A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0031479 CHEBI:81024 biolink:ChemicalSubstance nocardicin G go-plus.json http://purl.obolibrary.org/obo/CHEBI_81024 CHEBI:81021 biolink:ChemicalSubstance nocardicin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_81021 CHEBI:81022 biolink:ChemicalSubstance isonocardicin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_81022 GO:0031476 biolink:CellularComponent myosin VI complex A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0031476 GO:0031477 biolink:CellularComponent myosin VII complex A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain. go-plus.json http://purl.obolibrary.org/obo/GO_0031477 GO:0031474 biolink:CellularComponent myosin IV complex A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV. go-plus.json http://purl.obolibrary.org/obo/GO_0031474 GO:0031475 biolink:CellularComponent myosin V complex A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region. go-plus.json http://purl.obolibrary.org/obo/GO_0031475 GO:0031472 biolink:CellularComponent propanediol degradation polyhedral organelle An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase. go-plus.json http://purl.obolibrary.org/obo/GO_0031472 GO:0031473 biolink:MolecularActivity myosin III binding Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain. go-plus.json http://purl.obolibrary.org/obo/GO_0031473 GO:0031470 biolink:CellularComponent carboxysome An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO(2). It augments the concentration of CO(2) in the vicinity of RuBisCO to increase the efficiency of CO(2) fixation under atmospheric conditions. Wikipedia:Carboxysome go-plus.json http://purl.obolibrary.org/obo/GO_0031470 GO:0031471 biolink:CellularComponent ethanolamine degradation polyhedral organelle An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase. go-plus.json ethanolamine metabolosome http://purl.obolibrary.org/obo/GO_0031471 NCBITaxon:9822 biolink:OrganismalEntity Sus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9822 NCBITaxon:9823 biolink:OrganismalEntity Sus scrofa go-plus.json wild boar|pig|pigs|swine http://purl.obolibrary.org/obo/NCBITaxon_9823 UBERON:0003054 biolink:AnatomicalEntity roof plate A single row of glia at the dorsal midline of the developing neural tube along the entire anterior-posterior axis. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. go-plus.json roof plate neural tube|alar plate|future brain roof plate|roof plate neural tube region|roofplate http://purl.obolibrary.org/obo/UBERON_0003054 UBERON:0003055 biolink:AnatomicalEntity periderm A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis. go-plus.json EVL|epidermis outer layer|skin periderm|epitrichium|epidermis epithelial layer|periderm http://purl.obolibrary.org/obo/UBERON_0003055 UBERON:0003052 biolink:AnatomicalEntity midbrain-hindbrain boundary The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json mid-hindbrain boundary|isthmic organizer territory|isthmus|MHB|isthmus/MHB|midbrain hindbrain boundary|mid-hindbrain junction|isthmo-cerebellar region http://purl.obolibrary.org/obo/UBERON_0003052 UBERON:0003053 biolink:AnatomicalEntity ventricular zone Proliferative region that is part of the ventricular system. go-plus.json brain ventricular zone|VZ|ventricular zones|ventricular zone of brain http://purl.obolibrary.org/obo/UBERON_0003053 UBERON:0003050 biolink:AnatomicalEntity olfactory placode A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity. go-plus.json placoda olfactoria|olfactory placodes|placoda nasalis|nasal I placode|nasal placode http://purl.obolibrary.org/obo/UBERON_0003050 UBERON:0003051 biolink:AnatomicalEntity ear vesicle An epithelial sac of invaginated ectoderm formed from the otic placode that gives rise to the structures of the inner ear[MP] go-plus.json otic vesicle|acoustic vesicle|auditory vesicle|OV|otocyst http://purl.obolibrary.org/obo/UBERON_0003051 UBERON:0003058 biolink:AnatomicalEntity hypochord The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta[GO]. go-plus.json ipochord|subnotochordal rod http://purl.obolibrary.org/obo/UBERON_0003058 UBERON:0003059 biolink:AnatomicalEntity presomitic mesoderm Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. go-plus.json somitogenic mesoderm|segmental plate|presumptive somite mesoderm|unsegmented paraxial mesoderm|unsegmented mesenchyme|somitomeric mesoderm|PSM http://purl.obolibrary.org/obo/UBERON_0003059 UBERON:0003056 biolink:AnatomicalEntity pre-chordal neural plate The portion of neural plate anterior to the mid-hindbrain junction. go-plus.json anterior neural plate http://purl.obolibrary.org/obo/UBERON_0003056 UBERON:0003057 biolink:AnatomicalEntity chordal neural plate The portion of neural plate posterior to the mid-hindbrain junction. go-plus.json posterior neural plate http://purl.obolibrary.org/obo/UBERON_0003057 CHEBI:22629 biolink:ChemicalSubstance arsenate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22629 CHEBI:22633 biolink:ChemicalSubstance arsenite ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22633 CHEBI:22632 biolink:ChemicalSubstance arsenic molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_22632 UBERON:0003043 biolink:AnatomicalEntity posterior part of anterior commissure The major forebrain commissure that connects the two temporal lobes of the cortex. go-plus.json pars posterior|anterior commissure, temporal limb|anterior commissure temporal limb|anterior commissure pars posterior|anterior commissure, posterior part|temporal limb of anterior commissure|commissura anterior, pars posterior|commissura rostralis, pars posterior|pars posterior commissurae anterioris|commissura anterior, crus posterius http://purl.obolibrary.org/obo/UBERON_0003043 UBERON:0003041 biolink:AnatomicalEntity trigeminal nerve fibers A nerve fiber that is part of a trigeminal nerve. go-plus.json central part of trigeminal nerve|fibrae nervi trigemini|trigeminal nerve tract|trigeminal nerve fibers http://purl.obolibrary.org/obo/UBERON_0003041 CHEBI:22638 biolink:ChemicalSubstance organoarsonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22638 UBERON:0003049 biolink:AnatomicalEntity collagen and cuticulin-based cuticle A type of cuticle composed of highly cross-linked collagens and specialised insoluble proteins known as cuticlins, together with glycoproteins and lipids[WP]. go-plus.json nematode cuticle http://purl.obolibrary.org/obo/UBERON_0003049 UBERON:0017672 biolink:AnatomicalEntity abdominal viscera A viscus that is part of a abdomen. go-plus.json abdominal viscera set|abdominal viscera|set of abdominal viscera http://purl.obolibrary.org/obo/UBERON_0017672 CHEBI:22600 biolink:ChemicalSubstance arabinose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22600 CHEBI:22601 biolink:ChemicalSubstance arabinoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_22601 CHEBI:22605 biolink:ChemicalSubstance arabinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22605 UBERON:0003038 biolink:AnatomicalEntity thoracic spinal cord The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]. go-plus.json thoracic segments of spinal cord [1-12]|pars thoracica medullae spinalis|thoracic region of spinal cord|thoracic spinal cord|thoracic segment of spinal cord|segmenta thoracica medullae spinalis [1-12] http://purl.obolibrary.org/obo/UBERON_0003038 UBERON:0003039 biolink:AnatomicalEntity anterior commissure anterior part The horseshoe-shaped tract that connects the two olfactory bulbs. go-plus.json pars anterior|anterior commissure pars anterior|anterior commissure, anterior part|pars olfactoria commissurae anterioris|anterior part of anterior commissure|commissura anterior, pars olfactoria|anterior commissure olfactory limb|anterior commissure, olfactory limb|olfactory limb of anterior commissure|olfactory part of anterior commissure|commissura rostralis, pars anterior|commissura anterior, crus anterius|commissura anterior, pars anterior|pars anterior commissurae anterioris http://purl.obolibrary.org/obo/UBERON_0003039 CHEBI:22603 biolink:ChemicalSubstance arabinoxylans go-plus.json http://purl.obolibrary.org/obo/CHEBI_22603 UBERON:0003037 biolink:AnatomicalEntity septum A wall, dividing a cavity or structure into smaller ones[WP]. go-plus.json septa http://purl.obolibrary.org/obo/UBERON_0003037 NCBITaxon:9821 biolink:OrganismalEntity Suidae go-plus.json boars|pigs http://purl.obolibrary.org/obo/NCBITaxon_9821 UBERON:0003028 biolink:AnatomicalEntity commissure of inferior colliculus A commissure that is part of a inferior colliculus [Automatically generated definition]. go-plus.json posterior colliculus commissure|commissure of caudal colliculus|inferior colliculus commissure|commissure of posterior corpus quadrigeminum|commissure of the inferior colliculi|caudal colliculus commissure|commissura colliculorum inferiorum|commissure of inferior colliculi|inferior collicular commissure|commissure of the inferior colliculus|commissura colliculorum caudalium|posterior corpus quadrigeminum commissure|commissura colliculi inferioris|commissure of posterior colliculus http://purl.obolibrary.org/obo/UBERON_0003028 CHEBI:22619 biolink:ChemicalSubstance arginyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22619 UBERON:0003023 biolink:AnatomicalEntity pontine tegmentum Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133). go-plus.json dorsal pons|dorsal portion of pons|tegmentum pontis|tegmentum pontis|pars dorsalis pontis|pars posterior pontis|tegmentum of pons|tegmental portion of pons http://purl.obolibrary.org/obo/UBERON_0003023 CHEBI:22617 biolink:ChemicalSubstance arginine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_22617 UBERON:0003091 biolink:AnatomicalEntity thyroid primordium The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus. go-plus.json thyroid primordia http://purl.obolibrary.org/obo/UBERON_0003091 UBERON:0003098 biolink:AnatomicalEntity optic stalk the narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain go-plus.json optic stalks|pedunculus opticus http://purl.obolibrary.org/obo/UBERON_0003098 UBERON:0003099 biolink:AnatomicalEntity cranial neural crest neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. go-plus.json head crest|head neural crest|cranial NCC population|crista neuralis cranialis|head NCC population|CNC|cephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003099 UBERON:0003097 biolink:AnatomicalEntity dorsal fin Median fin located on the dorsal surface of the organism. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003097 UBERON:0003080 biolink:AnatomicalEntity anterior neural tube go-plus.json http://purl.obolibrary.org/obo/UBERON_0003080 CHEBI:71606 biolink:ChemicalSubstance salvianin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71606 chebi_ph7_3 CHEBI:71608 biolink:ChemicalSubstance cyclo(L-phenylalanyl-L-leucyl) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71608 chebi_ph7_3 CHEBI:71609 biolink:ChemicalSubstance albonoursin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71609 chebi_ph7_3 UBERON:0003085 biolink:AnatomicalEntity ventral aorta The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003085 UBERON:0003086 biolink:AnatomicalEntity caudal artery Extension of the dorsal aorta in the tail. go-plus.json CA http://purl.obolibrary.org/obo/UBERON_0003086 UBERON:0003083 biolink:AnatomicalEntity trunk neural crest Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. go-plus.json TNC|trunk crest http://purl.obolibrary.org/obo/UBERON_0003083 UBERON:0003084 biolink:AnatomicalEntity heart primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. go-plus.json fused heart primordium|cardiac field http://purl.obolibrary.org/obo/UBERON_0003084 UBERON:0003081 biolink:AnatomicalEntity lateral plate mesoderm Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. go-plus.json lateral mesoderm|lateral plate mesenchyme|mesoderma laminae lateralis|LPM|lateral plate http://purl.obolibrary.org/obo/UBERON_0003081 UBERON:0003082 biolink:AnatomicalEntity myotome A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. go-plus.json myotome region|myotomes|myomere|myotomus|myomeres|muscle plate http://purl.obolibrary.org/obo/UBERON_0003082 UBERON:0003089 biolink:AnatomicalEntity sclerotome Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. go-plus.json sclerotomes|sclerotomus http://purl.obolibrary.org/obo/UBERON_0003089 CHEBI:71613 biolink:ChemicalSubstance (25R)-Delta(4)-dafachronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71613 CHEBI:71616 biolink:ChemicalSubstance (25S)-cholestenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71616 NCBITaxon:9845 biolink:OrganismalEntity Ruminantia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9845 CHEBI:71618 biolink:ChemicalSubstance cyclo(dehydrophenylalanyl-L-leucyl) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71618 chebi_ph7_3 CHEBI:71619 biolink:ChemicalSubstance UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71619 UBERON:0003076 biolink:AnatomicalEntity posterior neural tube go-plus.json http://purl.obolibrary.org/obo/UBERON_0003076 UBERON:0003077 biolink:AnatomicalEntity paraxial mesoderm The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO] go-plus.json mesoderma paraxiale|paraxial mesenchyme|somitic mesoderm http://purl.obolibrary.org/obo/UBERON_0003077 UBERON:0003074 biolink:AnatomicalEntity mesonephric duct Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. go-plus.json archinephric duct|Leydig's duct|ductus mesonephricus; ductus Wolffi|Wolffian duct|renal duct http://purl.obolibrary.org/obo/UBERON_0003074 UBERON:0003075 biolink:AnatomicalEntity neural plate A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA] go-plus.json lamina neuralis|presumptive central nervous system http://purl.obolibrary.org/obo/UBERON_0003075 UBERON:0003072 biolink:AnatomicalEntity optic cup Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]. go-plus.json eye cup|eyecup|ophtalmic cup|ocular cup http://purl.obolibrary.org/obo/UBERON_0003072 UBERON:0003073 biolink:AnatomicalEntity lens placode A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]. go-plus.json lens placodes|placoda lentis http://purl.obolibrary.org/obo/UBERON_0003073 UBERON:0003070 biolink:AnatomicalEntity trigeminal placode complex A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion. go-plus.json trigeminal placodes|trigeminal placode|profundus placode|trigeminal V placode|profundus V placode http://purl.obolibrary.org/obo/UBERON_0003070 UBERON:0003071 biolink:AnatomicalEntity eye primordium Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. go-plus.json optic placodes|occular primordium|optic placode of camera-type eye|ocular primordium|eye anlage|eye field|eye placode|optic field|optic placode|optic primordium http://purl.obolibrary.org/obo/UBERON_0003071 UBERON:0003078 biolink:AnatomicalEntity epibranchial placode Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. go-plus.json ventrolateral placode|epibranchial placodes http://purl.obolibrary.org/obo/UBERON_0003078 UBERON:0003079 biolink:AnatomicalEntity floor plate The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube. go-plus.json floorplate|FP|bodenplatte|ventral plate http://purl.obolibrary.org/obo/UBERON_0003079 CHEBI:71624 biolink:ChemicalSubstance methanetelluronate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71624 chebi_ph7_3 UBERON:0003066 biolink:AnatomicalEntity pharyngeal arch 2 The second pharyngeal arch will form the hyoid apparatus. The cranial neural crest cells that populate the second pharyngeal arch emerge primarily from rhombomere 4 and will form skeletal elements. go-plus.json second pharyngeal arch|hyoid bars|pharyngeal arch 2|2nd visceral arch|hyoid arch|2nd pharyngeal arch|branchial arch 2|second branchial arch|second visceral arch|arcus pharyngeus secundus|visceral arch 2|pharyngeal arches 2|2nd arch http://purl.obolibrary.org/obo/UBERON_0003066 UBERON:0003063 biolink:AnatomicalEntity prechordal plate A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue go-plus.json head mesoderm|head mesenchyme http://purl.obolibrary.org/obo/UBERON_0003063 UBERON:0003064 biolink:AnatomicalEntity intermediate mesoderm The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. go-plus.json IM|intermediate plate mesoderm|mesenchyma intermedium|intermediate mesenchyme|intermediate plate http://purl.obolibrary.org/obo/UBERON_0003064 UBERON:0003061 biolink:AnatomicalEntity blood island Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. go-plus.json caudal hematopoietic tissue|blood islands|VBI|posterior blood island|ventral lateral plate mesoderm|ventral blood island|posterior ICM http://purl.obolibrary.org/obo/UBERON_0003061 UBERON:0003062 biolink:AnatomicalEntity primitive knot organizer for gastrulation in vertebrates. The primitive knot starts as a regional knot of cells that forms on the blastodisc immediately anterior to where the outer layer of cells will begin to migrate inwards - an area known as the primitive streak. Posterior to the node is the primitive pit, where the cells of the epiblast (the upper layer of embryonic cells) initially begin to invaginate. This invagination expands posteriorly into the primitive groove as the cells layers continue to move into the space between the embryonic cells and the yolk. This differentiates the embryo into the germ layers - endoderm, mesoderm, and ectoderm. The primitive knot migrates posteriorly as gastrulation proceeds, eventually being absorbed into the tail bud.[WP]. the regional thickening of cells at the rostral tip of the vertebrate primitive streak through which gastrulating cells migrate anteriorally to form tissues in the future head and neck; this region organizes the formation of the three embryonic layers and establishes the longitudinal axis and the polarity of the embryo[MP]. go-plus.json Spemann Mangold organizer|embryo organizer|primitive node|nodus primitivus|node|Spemann's organizer|Hensen node|Henson's node|organizer|embryonic shield|DMZ|Hensen's node|shield|embryonic organizer|dorsal marginal zone http://purl.obolibrary.org/obo/UBERON_0003062 UBERON:0003060 biolink:AnatomicalEntity pronephric duct In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. go-plus.json pronephric ducts|archinephric duct|ductus pronephricus http://purl.obolibrary.org/obo/UBERON_0003060 UBERON:0003069 biolink:AnatomicalEntity otic placode A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII[NBK] go-plus.json auditory placode|ear/otic placode|ear placode|octaval VIII placode|placoda otica|octaval placode http://purl.obolibrary.org/obo/UBERON_0003069 UBERON:0003067 biolink:AnatomicalEntity dorsolateral placode Lateral neurogenic placodes positioned dorsal of the epibranchial placodes. go-plus.json dorsolateral placodes http://purl.obolibrary.org/obo/UBERON_0003067 UBERON:0003068 biolink:AnatomicalEntity axial mesoderm The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. go-plus.json chordamesoderm http://purl.obolibrary.org/obo/UBERON_0003068 GO:0006429 biolink:BiologicalProcess leucyl-tRNA aminoacylation The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006429 GO:0006427 biolink:BiologicalProcess histidyl-tRNA aminoacylation The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006427 GO:0006428 biolink:BiologicalProcess isoleucyl-tRNA aminoacylation The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006428 GO:0006425 biolink:BiologicalProcess glutaminyl-tRNA aminoacylation The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006425 GO:0006426 biolink:BiologicalProcess glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006426 GO:0006423 biolink:BiologicalProcess cysteinyl-tRNA aminoacylation The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006423 GO:0006424 biolink:BiologicalProcess glutamyl-tRNA aminoacylation The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006424 UBERON:0017615 biolink:AnatomicalEntity vomerine dentition A set of teeth in which each tooth that attaches to a vomer. go-plus.json vomerine teeth http://purl.obolibrary.org/obo/UBERON_0017615 GO:0006421 biolink:BiologicalProcess asparaginyl-tRNA aminoacylation The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006421 GO:0006422 biolink:BiologicalProcess aspartyl-tRNA aminoacylation The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006422 GO:0006420 biolink:BiologicalProcess arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006420 CHEBI:32023 biolink:ChemicalSubstance plaunotol go-plus.json http://purl.obolibrary.org/obo/CHEBI_32023 chebi_ph7_3 CHEBI:4638 biolink:ChemicalSubstance diphenidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_4638 CHEBI:46662 biolink:ChemicalSubstance mineral go-plus.json http://purl.obolibrary.org/obo/CHEBI_46662 GO:0006438 biolink:BiologicalProcess valyl-tRNA aminoacylation The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006438 GO:0006439 biolink:BiologicalProcess obsolete aminoacyl-tRNA hydrolase reaction OBSOLETE. Hydrolysis of the peptidyl-tRNA by aminoacyl-tRNA hydrolase upon termination of translation. Analogous to usual peptidyl transfer during elongation, except that the acceptor is H2O instead of an aminoacyl-tRNA. go-plus.json aminoacyl-tRNA hydrolase reaction http://purl.obolibrary.org/obo/GO_0006439 GO:0006436 biolink:BiologicalProcess tryptophanyl-tRNA aminoacylation The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006436 GO:0006437 biolink:BiologicalProcess tyrosyl-tRNA aminoacylation The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006437 GO:0006434 biolink:BiologicalProcess seryl-tRNA aminoacylation The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006434 CHEBI:46668 biolink:ChemicalSubstance amino acid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_46668 GO:0006435 biolink:BiologicalProcess threonyl-tRNA aminoacylation The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006435 GO:0006432 biolink:BiologicalProcess phenylalanyl-tRNA aminoacylation The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006432 GO:0006433 biolink:BiologicalProcess prolyl-tRNA aminoacylation The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006433 GO:0006430 biolink:BiologicalProcess lysyl-tRNA aminoacylation The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006430 GO:0006431 biolink:BiologicalProcess methionyl-tRNA aminoacylation The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. go-plus.json http://purl.obolibrary.org/obo/GO_0006431 CHEBI:4648 biolink:ChemicalSubstance hop-22(29)-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_4648 chebi_ph7_3 GO:0006407 biolink:BiologicalProcess rRNA export from nucleus The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins. go-plus.json rRNA export out of nucleus|rRNA-nucleus export|rRNA export from cell nucleus|rRNA transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0006407 GO:0006408 biolink:BiologicalProcess snRNA export from nucleus The directed movement of snRNA from the nucleus to the cytoplasm. go-plus.json snRNA transport from nucleus to cytoplasm|snRNA export from cell nucleus|snRNA export out of nucleus|snRNA-nucleus export http://purl.obolibrary.org/obo/GO_0006408 GO:0006405 biolink:BiologicalProcess RNA export from nucleus The directed movement of RNA from the nucleus to the cytoplasm. go-plus.json RNA export from cell nucleus|RNA transport from nucleus to cytoplasm|RNA export out of nucleus|RNA-nucleus export http://purl.obolibrary.org/obo/GO_0006405 CHEBI:22682 biolink:ChemicalSubstance azobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_22682 GO:0006406 biolink:BiologicalProcess mRNA export from nucleus The directed movement of mRNA from the nucleus to the cytoplasm. go-plus.json mRNA export out of nucleus|mRNA-nucleus export|mRNA transport from nucleus to cytoplasm|mRNA export from cell nucleus http://purl.obolibrary.org/obo/GO_0006406 GO:0006403 biolink:BiologicalProcess RNA localization A process in which RNA is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of RNA localization|RNA localisation http://purl.obolibrary.org/obo/GO_0006403 goslim_drosophila GO:0006404 biolink:BiologicalProcess RNA import into nucleus The import of RNA from the cytoplasm to the nucleus. go-plus.json RNA-nucleus import|RNA import into cell nucleus|RNA transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0006404 GO:0006401 biolink:BiologicalProcess RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. go-plus.json RNA degradation|RNA catabolism|RNA breakdown http://purl.obolibrary.org/obo/GO_0006401 goslim_yeast|goslim_drosophila GO:0006402 biolink:BiologicalProcess mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. go-plus.json mRNA degradation|mRNA breakdown|mRNA catabolism|mRNA decay http://purl.obolibrary.org/obo/GO_0006402 GO:0006400 biolink:BiologicalProcess tRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. go-plus.json tRNA editing http://purl.obolibrary.org/obo/GO_0006400 NCBITaxon:9895 biolink:OrganismalEntity Bovidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9895 GO:0006409 biolink:BiologicalProcess tRNA export from nucleus The directed movement of tRNA from the nucleus to the cytoplasm. go-plus.json tRNA-nucleus export|tRNA export out of nucleus|tRNA export from cell nucleus|tRNA transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0006409 GO:0006418 biolink:BiologicalProcess tRNA aminoacylation for protein translation The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis. MetaCyc:TRNA-CHARGING-PWY go-plus.json tRNA charging http://purl.obolibrary.org/obo/GO_0006418 goslim_yeast CHEBI:46640 biolink:ChemicalSubstance diketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_46640 CHEBI:22695 biolink:ChemicalSubstance base go-plus.json http://purl.obolibrary.org/obo/CHEBI_22695 GO:0006419 biolink:BiologicalProcess alanyl-tRNA aminoacylation The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0006419 GO:0006416 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006416 CHEBI:22693 biolink:ChemicalSubstance barbiturates go-plus.json http://purl.obolibrary.org/obo/CHEBI_22693 GO:0006417 biolink:BiologicalProcess regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. go-plus.json regulation of protein anabolism|regulation of protein synthesis|regulation of protein formation|regulation of protein biosynthesis http://purl.obolibrary.org/obo/GO_0006417 goslim_yeast GO:0006414 biolink:BiologicalProcess translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. go-plus.json translation elongation|protein synthesis elongation http://purl.obolibrary.org/obo/GO_0006414 goslim_yeast CHEBI:46644 biolink:ChemicalSubstance D-altronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46644 GO:0006415 biolink:BiologicalProcess translational termination The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). go-plus.json translational complex disassembly|translation termination|protein synthesis termination http://purl.obolibrary.org/obo/GO_0006415 CHEBI:46645 biolink:ChemicalSubstance isobutanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46645 chebi_ph7_3 GO:0006412 biolink:BiologicalProcess translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. Wikipedia:Translation_(genetics) go-plus.json protein biosynthetic process|protein biosynthesis|protein anabolism|protein synthesis|protein formation|protein translation http://purl.obolibrary.org/obo/GO_0006412 goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl GO:0006413 biolink:BiologicalProcess translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. go-plus.json translation initiation|biopolymerisation|protein synthesis initiation|biopolymerization http://purl.obolibrary.org/obo/GO_0006413 goslim_yeast CHEBI:22698 biolink:ChemicalSubstance benzaldehydes go-plus.json http://purl.obolibrary.org/obo/CHEBI_22698 GO:0006410 biolink:BiologicalProcess obsolete transcription, RNA-dependent OBSOLETE. The cellular synthesis of DNA on a template of RNA. go-plus.json transcription, RNA-dependent http://purl.obolibrary.org/obo/GO_0006410 GO:0006411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006411 CHEBI:4629 biolink:ChemicalSubstance diosgenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_4629 chebi_ph7_3 CHEBI:22691 biolink:ChemicalSubstance barbiturate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22691 CHEBI:4623 biolink:ChemicalSubstance (carboxymethyl)(dimethyl)sulfonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_4623 UBERON:0017651 biolink:AnatomicalEntity salivary gland primordium A primordium that has the potential to develop into a saliva-secreting gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0017651 CHEBI:22660 biolink:ChemicalSubstance aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22660 UBERON:0017650 biolink:AnatomicalEntity developing mesenchymal structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. go-plus.json http://purl.obolibrary.org/obo/UBERON_0017650 CHEBI:22661 biolink:ChemicalSubstance aspartic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_22661 CHEBI:46633 biolink:ChemicalSubstance carbapenems go-plus.json http://purl.obolibrary.org/obo/CHEBI_46633 CHEBI:46634 biolink:ChemicalSubstance carbapenemcarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46634 UBERON:0017659 biolink:AnatomicalEntity ventral surface of penis go-plus.json urethral surface of penis http://purl.obolibrary.org/obo/UBERON_0017659 CHEBI:4676 biolink:ChemicalSubstance dodecanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4676 CHEBI:46638 biolink:ChemicalSubstance O-sinapoyl-D-glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46638 CHEBI:22669 biolink:ChemicalSubstance aspulvinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_22669 CHEBI:4672 biolink:ChemicalSubstance docetaxel anhydrous go-plus.json http://purl.obolibrary.org/obo/CHEBI_4672 chebi_ph7_3 CHEBI:22676 biolink:ChemicalSubstance auxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22676 UBERON:0017648 biolink:AnatomicalEntity ventral body wall The ventral part of the body wall go-plus.json anterior body wall http://purl.obolibrary.org/obo/UBERON_0017648 UBERON:0017649 biolink:AnatomicalEntity dorsal body wall The dorsal part of the body wall go-plus.json http://purl.obolibrary.org/obo/UBERON_0017649 CHEBI:46629 biolink:ChemicalSubstance oxo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_46629 chebi_ph7_3 CHEBI:46611 biolink:ChemicalSubstance phosphorothioic O,O,O-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46611 CHEBI:22644 biolink:ChemicalSubstance arylalkylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22644 CHEBI:46612 biolink:ChemicalSubstance phosphorothioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46612 CHEBI:22645 biolink:ChemicalSubstance arenecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22645 CHEBI:46613 biolink:ChemicalSubstance phosphorothioic O,O,S-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46613 UBERON:0017628 biolink:AnatomicalEntity swim bladder gas gland A structure with numerous blood vessels (retia mirabilia) in the gas bladder that secretes gases from the blood. go-plus.json red gland|fascis mirabilis|red gland of gas bladder|gas gland http://purl.obolibrary.org/obo/UBERON_0017628 CHEBI:22648 biolink:ChemicalSubstance arylmercury compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_22648 CHEBI:22651 biolink:ChemicalSubstance ascorbate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22651 CHEBI:22652 biolink:ChemicalSubstance ascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22652 CHEBI:22656 biolink:ChemicalSubstance asparaginyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22656 chebi_ph7_3 CHEBI:22653 biolink:ChemicalSubstance asparagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22653 CHEBI:22654 biolink:ChemicalSubstance asparagine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_22654 CHEBI:22658 biolink:ChemicalSubstance aspartate family amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22658 GO:0031588 biolink:CellularComponent nucleotide-activated protein kinase complex A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae). go-plus.json 5'-AMP-activated protein kinase complex|SNF1/AMPK protein kinase complex|ADP-activated protein kinase complex|AMPK complex|Snf1 kinase complex|Snf1 serine/threonine protein kinase complex|AMP-activated protein kinase complex http://purl.obolibrary.org/obo/GO_0031588 GO:0031589 biolink:BiologicalProcess cell-substrate adhesion The attachment of a cell to the underlying substrate via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0031589 GO:0031586 biolink:BiologicalProcess negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. go-plus.json downregulation of IP3 receptor activity|negative regulation of inositol 1,4,5-trisphosphate receptor activity|down-regulation of IP3 receptor activity|inhibition of IP3 receptor activity|negative regulation of IP3 receptor activity|down regulation of IP3 receptor activity http://purl.obolibrary.org/obo/GO_0031586 GO:0031587 biolink:BiologicalProcess positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. go-plus.json positive regulation of inositol-1,4,5-trisphosphate receptor activity|up regulation of IP3 receptor activity|activation of IP3 receptor activity|stimulation of IP3 receptor activity|up-regulation of IP3 receptor activity|positive regulation of IP3 receptor activity|upregulation of IP3 receptor activity http://purl.obolibrary.org/obo/GO_0031587 CHEBI:136282 biolink:ChemicalSubstance 9-[(9Z)-octadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136282 chebi_ph7_3 GO:0031584 biolink:BiologicalProcess activation of phospholipase D activity Any process that initiates the activity of inactive phospholipase D. go-plus.json http://purl.obolibrary.org/obo/GO_0031584 GO:0031585 biolink:BiologicalProcess regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. go-plus.json regulation of IP3 receptor activity|regulation of inositol-1,4,5-triphosphate receptor activity http://purl.obolibrary.org/obo/GO_0031585 CHEBI:4470 biolink:ChemicalSubstance dextromethorphan go-plus.json http://purl.obolibrary.org/obo/CHEBI_4470 GO:0031582 biolink:BiologicalProcess replication fork arrest at rDNA repeats A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer. go-plus.json replication fork blocking at rDNA repeats|replication fork arrest at ribosomal DNA repeats http://purl.obolibrary.org/obo/GO_0031582 GO:0031583 biolink:BiologicalProcess phospholipase D-activating G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA). go-plus.json phospholipase D-activating G-protein coupled receptor signaling pathway|G-protein signalling, phospholipase D activating pathway|activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway http://purl.obolibrary.org/obo/GO_0031583 GO:0031580 biolink:BiologicalProcess membrane raft distribution The process that establishes the spatial arrangement of membrane rafts within a cellular membrane. go-plus.json lipid raft distribution http://purl.obolibrary.org/obo/GO_0031580 CHEBI:136286 biolink:ChemicalSubstance 9-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136286 chebi_ph7_3 GO:0031581 biolink:BiologicalProcess hemidesmosome assembly Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina. go-plus.json http://purl.obolibrary.org/obo/GO_0031581 GO:0031579 biolink:BiologicalProcess membrane raft organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. go-plus.json membrane raft organization and biogenesis|membrane raft organisation|lipid raft organization http://purl.obolibrary.org/obo/GO_0031579 GO:0031577 biolink:BiologicalProcess spindle checkpoint signaling A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle. Wikipedia:Spindle_checkpoint go-plus.json signal transduction involved in spindle checkpoint|spindle checkpoint http://purl.obolibrary.org/obo/GO_0031577 gocheck_do_not_manually_annotate GO:0031578 biolink:BiologicalProcess mitotic spindle orientation checkpoint signaling A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected. go-plus.json spindle position checkpoint|SPOC|mitotic cell cycle spindle orientation checkpoint|SOC|mitotic spindle orientation checkpoint|signal transduction involved in mitotic cell cycle spindle orientation checkpoint http://purl.obolibrary.org/obo/GO_0031578 GO:0031575 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031575 GO:0031576 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031576 GO:0031573 biolink:BiologicalProcess mitotic intra-S DNA damage checkpoint signaling A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression. go-plus.json S-phase checkpoint|intra-S DNA damage checkpoint|mitotic intra-S DNA damage checkpoint|signal transduction involved in intra-S DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0031573 GO:0031574 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031574 GO:0031571 biolink:BiologicalProcess mitotic G1 DNA damage checkpoint signaling A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint. go-plus.json intracellular signaling cascade involved in G1/S DNA damage checkpoint|G1/S DNA damage checkpoint|intracellular signaling cascade involved in G1 DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint|G1 DNA damage checkpoint|intracellular signal transduction involved in G1/S DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint|intracellular signaling chain involved in G1/S DNA damage checkpoint|intracellular signaling chain involved in G1 DNA damage checkpoint|signal transduction involved in mitotic G1 DNA damage checkpoint|intracellular signal transduction pathway involved in G1/S DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint|signal transmission via intracellular cascade involved in G1 DNA damage checkpoint|intracellular signal transduction pathway involved in G1 DNA damage checkpoint|intracellular signaling pathway involved in G1/S DNA damage checkpoint|mitotic G1 DNA damage checkpoint|intracellular signaling pathway involved in G1 DNA damage checkpoint|intracellular signal transduction involved in G1 DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0031571 GO:0031572 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031572 GO:0031570 biolink:BiologicalProcess DNA integrity checkpoint signaling A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes. go-plus.json signal transduction involved in DNA integrity checkpoint|DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_0031570 GO:0031568 biolink:BiologicalProcess mitotic G1 cell size control checkpoint signaling A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle. go-plus.json signal transduction involved in mitotic cell cycle G1/S transition size control checkpoint|mitotic cell cycle G1/S transition size control checkpoint|G1 cell size control checkpoint|mitotic G1 cell size control checkpoint|G1 cell size control checkpoint signalling|signal transduction involved in G1 cell size control checkpoint http://purl.obolibrary.org/obo/GO_0031568 GO:0031569 biolink:BiologicalProcess mitotic G2 cell size control checkpoint signaling A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis. go-plus.json signal transduction involved in G2 cell size control checkpoint|signal transduction involved in mitotic cell cycle G2/M transition size control checkpoint|signal transduction involved in G2/M transition size control checkpoint|mitotic cell cycle G2/M transition size control checkpoint|G2 cell size control checkpoint|G2/M transition size control checkpoint|mitotic G2 cell size control checkpoint http://purl.obolibrary.org/obo/GO_0031569 GO:0031566 biolink:BiologicalProcess actomyosin contractile ring maintenance The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle. go-plus.json contractile ring maintenance involved in cell cycle cytokinesis|cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle http://purl.obolibrary.org/obo/GO_0031566 GO:0031567 biolink:BiologicalProcess mitotic cell size control checkpoint signaling A signal transduction process that contributes to a cell size control checkpoint during mitosis. go-plus.json signal transduction involved in cell size control checkpoint|mitotic cell cycle cell size control checkpoint|mitotic cell size control checkpoint http://purl.obolibrary.org/obo/GO_0031567 GO:0031564 biolink:BiologicalProcess transcription antitermination Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s). go-plus.json transcriptional readthrough http://purl.obolibrary.org/obo/GO_0031564 PR:000017283 biolink:Protein vitamin D3 receptor A protein that is a translation product of the human VDR gene or a 1:1 ortholog thereof. go-plus.json NR1I1|VDR|1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1 http://purl.obolibrary.org/obo/PR_000017283 GO:0031565 biolink:BiologicalProcess obsolete cytokinesis checkpoint OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition. go-plus.json septin checkpoint|contractile ring checkpoint http://purl.obolibrary.org/obo/GO_0031565 GO:0031562 biolink:CellularComponent hyphal tip polarisome Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha. go-plus.json http://purl.obolibrary.org/obo/GO_0031562 GO:0031563 biolink:CellularComponent mating projection tip polarisome Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone. go-plus.json http://purl.obolibrary.org/obo/GO_0031563 GO:0031560 biolink:CellularComponent cellular bud neck polarisome Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0031560 GO:0031561 biolink:CellularComponent cellular bud tip polarisome Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud. go-plus.json http://purl.obolibrary.org/obo/GO_0031561 GO:0031559 biolink:MolecularActivity oxidosqualene cyclase activity Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene. go-plus.json 2,3-oxidosqualene cyclase activity http://purl.obolibrary.org/obo/GO_0031559 GO:0031557 biolink:BiologicalProcess obsolete induction of programmed cell death in response to chemical stimulus OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus. go-plus.json induction of programmed cell death in response to chemical substance|induction of programmed cell death in response to chemical stimulus http://purl.obolibrary.org/obo/GO_0031557 GO:0031558 biolink:BiologicalProcess obsolete induction of apoptosis in response to chemical stimulus OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus. go-plus.json induction of apoptosis in response to chemical stimulus|induction of apoptosis in response to chemical substance http://purl.obolibrary.org/obo/GO_0031558 GO:0031555 biolink:BiologicalProcess transcriptional attenuation Regulation of transcription through variation in where transcription termination occurs. Wikipedia:Attenuator_(genetics) go-plus.json http://purl.obolibrary.org/obo/GO_0031555 GO:0031556 biolink:BiologicalProcess transcriptional attenuation by ribosome A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch. go-plus.json ribosome-mediated transcriptional attenuation http://purl.obolibrary.org/obo/GO_0031556 CHEBI:4469 biolink:ChemicalSubstance (S)-amphetamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_4469 PR:000017272 biolink:Protein vinculin A protein that is a translation product of the human VCL gene or a 1:1 ortholog thereof. go-plus.json VCL|metavinculin http://purl.obolibrary.org/obo/PR_000017272 GO:0031553 biolink:BiologicalProcess positive regulation of brain-derived neurotrophic factor-activated receptor activity Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. go-plus.json up-regulation of brain-derived neurotrophic factor receptor activity|upregulation of brain-derived neurotrophic factor receptor activity|positive regulation of brain-derived neurotrophic factor receptor activity|up regulation of brain-derived neurotrophic factor receptor activity|positive regulation of BDNF receptor activity|activation of brain-derived neurotrophic factor receptor activity|stimulation of brain-derived neurotrophic factor receptor activity http://purl.obolibrary.org/obo/GO_0031553 GO:0031554 biolink:BiologicalProcess regulation of DNA-templated transcription, termination Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. go-plus.json regulation of termination of DNA-dependent transcription|regulation of DNA-dependent transcription, termination|transcription antiterminator activity|regulation of transcription termination, DNA-dependent http://purl.obolibrary.org/obo/GO_0031554 GO:0031551 biolink:BiologicalProcess regulation of brain-derived neurotrophic factor-activated receptor activity Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. go-plus.json regulation of brain-derived neurotrophic factor receptor activity|regulation of BDNF receptor activity http://purl.obolibrary.org/obo/GO_0031551 GO:0031552 biolink:BiologicalProcess negative regulation of brain-derived neurotrophic factor-activated receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. go-plus.json inhibition of brain-derived neurotrophic factor receptor activity|down regulation of brain-derived neurotrophic factor receptor activity|negative regulation of BDNF receptor activity|downregulation of brain-derived neurotrophic factor receptor activity|negative regulation of brain-derived neurotrophic factor receptor activity|down-regulation of brain-derived neurotrophic factor receptor activity http://purl.obolibrary.org/obo/GO_0031552 GO:0031550 biolink:BiologicalProcess positive regulation of brain-derived neurotrophic factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. go-plus.json stimulation of brain-derived neurotrophic factor receptor signaling pathway|up-regulation of brain-derived neurotrophic factor receptor signaling pathway|activation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of BDNF receptor signaling pathway|up regulation of brain-derived neurotrophic factor receptor signaling pathway|upregulation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of BDNF receptor signalling pathway|positive regulation of brain-derived neurotrophic factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031550 GO:0031548 biolink:BiologicalProcess regulation of brain-derived neurotrophic factor receptor signaling pathway Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. go-plus.json regulation of BDNF receptor signaling pathway|regulation of brain-derived neurotrophic factor receptor signalling pathway|regulation of BDNF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031548 GO:0031549 biolink:BiologicalProcess negative regulation of brain-derived neurotrophic factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. go-plus.json down-regulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of BDNF receptor signaling pathway|downregulation of brain-derived neurotrophic factor receptor signaling pathway|down regulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of BDNF receptor signalling pathway|inhibition of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of brain-derived neurotrophic factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031549 GO:0031546 biolink:MolecularActivity brain-derived neurotrophic factor receptor binding Binding to a brain-derived neurotrophic factor receptor. go-plus.json BDNF receptor binding|brain-derived neurotrophic factor ligand http://purl.obolibrary.org/obo/GO_0031546 GO:0031547 biolink:BiologicalProcess brain-derived neurotrophic factor receptor signaling pathway The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands. go-plus.json BDNF signalling pathway|BDNF receptor signaling pathway|brain-derived neurotrophic factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031547 GO:0006588 biolink:BiologicalProcess activation of tryptophan 5-monooxygenase activity The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity. go-plus.json tryptophan hydroxylase activation http://purl.obolibrary.org/obo/GO_0006588 GO:0031544 biolink:MolecularActivity peptidyl-proline 3-dioxygenase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2. go-plus.json http://purl.obolibrary.org/obo/GO_0031544 GO:0006589 biolink:BiologicalProcess octopamine biosynthetic process The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. go-plus.json octopamine synthesis|octopamine formation|octopamine biosynthesis|octopamine anabolism http://purl.obolibrary.org/obo/GO_0006589 GO:0031545 biolink:MolecularActivity peptidyl-proline 4-dioxygenase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2. Reactome:R-HSA-1234181|Reactome:R-HSA-1234179|Reactome:R-HSA-1234177|Reactome:R-HSA-1234173|Reactome:R-HSA-1234166|Reactome:R-HSA-1234165 go-plus.json prolyl 4-hydroxylase|HIF-type prolyl 4-hydroxylase http://purl.obolibrary.org/obo/GO_0031545 GO:0006586 biolink:BiologicalProcess indolalkylamine metabolic process The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. go-plus.json indolamine metabolism|indolamine metabolic process|indolalkylamine metabolism http://purl.obolibrary.org/obo/GO_0006586 GO:0006587 biolink:BiologicalProcess serotonin biosynthetic process from tryptophan The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. go-plus.json serotonin formation from tryptophan|serotonin anabolism from tryptophan|serotonin synthesis from tryptophan http://purl.obolibrary.org/obo/GO_0006587 GO:0006584 biolink:BiologicalProcess catecholamine metabolic process The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. go-plus.json catecholamine metabolism http://purl.obolibrary.org/obo/GO_0006584 GO:0006585 biolink:BiologicalProcess dopamine biosynthetic process from tyrosine The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine. go-plus.json dopamine formation from tyrosine|dopamine anabolism from tyrosine|dopamine synthesis from tyrosine http://purl.obolibrary.org/obo/GO_0006585 GO:0006582 biolink:BiologicalProcess melanin metabolic process The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. go-plus.json melanin metabolism http://purl.obolibrary.org/obo/GO_0006582 GO:0006583 biolink:BiologicalProcess melanin biosynthetic process from tyrosine The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine. go-plus.json melanin anabolism from tyrosine|melanin synthesis from tyrosine|melanin formation from tyrosine http://purl.obolibrary.org/obo/GO_0006583 GO:0006580 biolink:BiologicalProcess ethanolamine metabolic process The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). go-plus.json ethanolamine metabolism http://purl.obolibrary.org/obo/GO_0006580 GO:0006581 biolink:BiologicalProcess acetylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. go-plus.json acetylcholine degradation|acetylcholine breakdown|acetylcholine catabolism http://purl.obolibrary.org/obo/GO_0006581 GO:0006590 biolink:BiologicalProcess thyroid hormone generation The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0006590 GO:0031542 biolink:BiologicalProcess positive regulation of anthocyanin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins. go-plus.json positive regulation of anthocyanin biosynthesis|positive regulation of anthocyanin synthesis|up regulation of anthocyanin biosynthetic process|positive regulation of anthocyanin formation|upregulation of anthocyanin biosynthetic process|stimulation of anthocyanin biosynthetic process|up-regulation of anthocyanin biosynthetic process|activation of anthocyanin biosynthetic process|positive regulation of anthocyanin anabolism http://purl.obolibrary.org/obo/GO_0031542 GO:0031543 biolink:MolecularActivity peptidyl-proline dioxygenase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2. go-plus.json prolyl hydroxylase activity|prolyl 4-hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity|proline hydroxylase activity http://purl.obolibrary.org/obo/GO_0031543 GO:0031540 biolink:BiologicalProcess regulation of anthocyanin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins. go-plus.json regulation of anthocyanin biosynthesis|regulation of anthocyanin anabolism|regulation of anthocyanin synthesis|regulation of anthocyanin formation http://purl.obolibrary.org/obo/GO_0031540 GO:0031541 biolink:BiologicalProcess negative regulation of anthocyanin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins. go-plus.json negative regulation of anthocyanin anabolism|negative regulation of anthocyanin synthesis|downregulation of anthocyanin biosynthetic process|negative regulation of anthocyanin formation|down regulation of anthocyanin biosynthetic process|inhibition of anthocyanin biosynthetic process|negative regulation of anthocyanin biosynthesis|down-regulation of anthocyanin biosynthetic process http://purl.obolibrary.org/obo/GO_0031541 CHEBI:136243 biolink:ChemicalSubstance phosphatidylinositol 34:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136243 GO:0031539 biolink:BiologicalProcess positive regulation of anthocyanin metabolic process Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. go-plus.json up regulation of anthocyanin metabolic process|activation of anthocyanin metabolic process|stimulation of anthocyanin metabolic process|up-regulation of anthocyanin metabolic process|positive regulation of anthocyanin metabolism|upregulation of anthocyanin metabolic process http://purl.obolibrary.org/obo/GO_0031539 GO:0031537 biolink:BiologicalProcess regulation of anthocyanin metabolic process Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. go-plus.json regulation of anthocyanin metabolism http://purl.obolibrary.org/obo/GO_0031537 GO:0031538 biolink:BiologicalProcess negative regulation of anthocyanin metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. go-plus.json downregulation of anthocyanin metabolic process|down-regulation of anthocyanin metabolic process|inhibition of anthocyanin metabolic process|negative regulation of anthocyanin metabolism|down regulation of anthocyanin metabolic process http://purl.obolibrary.org/obo/GO_0031538 GO:0031535 biolink:BiologicalProcess plus-end directed microtubule sliding The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0031535 GO:0031536 biolink:BiologicalProcess positive regulation of exit from mitosis Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity). go-plus.json upregulation of exit from mitosis|up regulation of exit from mitosis|activation of exit from mitosis|stimulation of exit from mitosis|up-regulation of exit from mitosis http://purl.obolibrary.org/obo/GO_0031536 GO:0031533 biolink:CellularComponent mRNA cap methyltransferase complex A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping. go-plus.json mRNA (guanine-N7) methyltransferase complex|mRNA capping enzyme complex http://purl.obolibrary.org/obo/GO_0031533 GO:0006599 biolink:BiologicalProcess phosphagen metabolic process The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. go-plus.json phosphagen metabolism http://purl.obolibrary.org/obo/GO_0006599 GO:0031534 biolink:BiologicalProcess minus-end directed microtubule sliding The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0031534 GO:0006597 biolink:BiologicalProcess spermine biosynthetic process The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging. go-plus.json spermine anabolism|spermine synthesis|spermine biosynthesis|spermine formation http://purl.obolibrary.org/obo/GO_0006597 GO:0006598 biolink:BiologicalProcess polyamine catabolic process The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups. go-plus.json polyamine degradation|polyamine breakdown|polyamine catabolism http://purl.obolibrary.org/obo/GO_0006598 GO:0006595 biolink:BiologicalProcess polyamine metabolic process The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups. go-plus.json polyamine metabolism http://purl.obolibrary.org/obo/GO_0006595 GO:0006596 biolink:BiologicalProcess polyamine biosynthetic process The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. MetaCyc:POLYAMSYN-PWY go-plus.json polyamine biosynthesis|polyamine anabolism|polyamine synthesis|polyamine formation http://purl.obolibrary.org/obo/GO_0006596 GO:0006593 biolink:BiologicalProcess ornithine catabolic process The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. go-plus.json ornithine degradation|ornithine breakdown|ornithine catabolism http://purl.obolibrary.org/obo/GO_0006593 GO:0006594 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006594 GO:0006591 biolink:BiologicalProcess ornithine metabolic process The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. go-plus.json ornithine metabolism http://purl.obolibrary.org/obo/GO_0006591 GO:0006592 biolink:BiologicalProcess ornithine biosynthetic process The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. go-plus.json ornithine anabolism|ornithine synthesis|ornithine formation|ornithine biosynthesis http://purl.obolibrary.org/obo/GO_0006592 CHEBI:136257 biolink:ChemicalSubstance phosphatidylserine 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136257 GO:0031531 biolink:MolecularActivity thyrotropin-releasing hormone receptor binding Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary. go-plus.json thyrotropin-releasing hormone receptor ligand|thyrotropin releasing hormone receptor binding http://purl.obolibrary.org/obo/GO_0031531 GO:0031532 biolink:BiologicalProcess actin cytoskeleton reorganization A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins. go-plus.json actin cytoskeleton reorganisation|actin cytoskeleton remodeling http://purl.obolibrary.org/obo/GO_0031532 GO:0031530 biolink:MolecularActivity gonadotropin-releasing hormone receptor binding Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. go-plus.json gonadotrophin-releasing hormone receptor binding|GnRH receptor binding http://purl.obolibrary.org/obo/GO_0031530 CHEBI:136256 biolink:ChemicalSubstance phosphatidylserine 36:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136256 GO:0031528 biolink:CellularComponent microvillus membrane The portion of the plasma membrane surrounding a microvillus. go-plus.json http://purl.obolibrary.org/obo/GO_0031528 GO:0031529 biolink:BiologicalProcess ruffle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell. go-plus.json ruffle organization and biogenesis|ruffle organisation http://purl.obolibrary.org/obo/GO_0031529 GO:0031526 biolink:CellularComponent brush border membrane The portion of the plasma membrane surrounding the brush border. go-plus.json http://purl.obolibrary.org/obo/GO_0031526 GO:0031527 biolink:CellularComponent filopodium membrane The portion of the plasma membrane surrounding a filopodium. go-plus.json http://purl.obolibrary.org/obo/GO_0031527 GO:0031524 biolink:BiologicalProcess menthol metabolic process The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol. go-plus.json menthol metabolism http://purl.obolibrary.org/obo/GO_0031524 GO:0006568 biolink:BiologicalProcess tryptophan metabolic process The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. Wikipedia:Tryptophan go-plus.json tryptophan metabolism http://purl.obolibrary.org/obo/GO_0006568 GO:0031525 biolink:BiologicalProcess menthol biosynthetic process The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol. go-plus.json menthol biosynthesis|menthol anabolism|menthol synthesis|menthol formation http://purl.obolibrary.org/obo/GO_0031525 GO:0006569 biolink:BiologicalProcess tryptophan catabolic process The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. go-plus.json tryptophan catabolic process, using tryptophanase|tryptophan degradation|tryptophan catabolism|tryptophan catabolism, using tryptophanase|tryptophan breakdown http://purl.obolibrary.org/obo/GO_0006569 GO:0006566 biolink:BiologicalProcess threonine metabolic process The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. UM-BBD_pathwayID:met go-plus.json methionine and threonine metabolism|threonine metabolism|methionine and threonine metabolic process http://purl.obolibrary.org/obo/GO_0006566 GO:0031522 biolink:CellularComponent cell envelope Sec protein transport complex A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC. go-plus.json plasma membrane Sec complex|Sec translocation complex|Sec secretion complex|Sec complex http://purl.obolibrary.org/obo/GO_0031522 GO:0006567 biolink:BiologicalProcess threonine catabolic process The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. MetaCyc:THREOCAT-PWY|UM-BBD_pathwayID:met go-plus.json threonine degradation|threonine breakdown|threonine catabolism http://purl.obolibrary.org/obo/GO_0006567 GO:0031523 biolink:CellularComponent Myb complex A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression. go-plus.json Myeloblastosis proto-oncogene protein complex http://purl.obolibrary.org/obo/GO_0031523 GO:0006564 biolink:BiologicalProcess L-serine biosynthetic process The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. MetaCyc:SERSYN-PWY go-plus.json L-serine anabolism|L-serine synthesis|L-serine formation|L-serine biosynthesis http://purl.obolibrary.org/obo/GO_0006564 GO:0006565 biolink:BiologicalProcess L-serine catabolic process The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. MetaCyc:SERDEG-PWY go-plus.json L-serine degradation|L-serine breakdown|L-serine catabolism http://purl.obolibrary.org/obo/GO_0006565 GO:0006562 biolink:BiologicalProcess proline catabolic process The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. go-plus.json proline degradation|proline breakdown|proline catabolism http://purl.obolibrary.org/obo/GO_0006562 GO:0006563 biolink:BiologicalProcess L-serine metabolic process The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. go-plus.json L-serine metabolism http://purl.obolibrary.org/obo/GO_0006563 GO:0006560 biolink:BiologicalProcess proline metabolic process The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. go-plus.json proline metabolism http://purl.obolibrary.org/obo/GO_0006560 GO:0006561 biolink:BiologicalProcess proline biosynthetic process The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. MetaCyc:PROSYN-PWY|MetaCyc:PWY-3341 go-plus.json proline anabolism|proline synthesis|proline formation|proline biosynthesis http://purl.obolibrary.org/obo/GO_0006561 GO:0031520 biolink:CellularComponent plasma membrane of cell tip The portion of the plasma membrane surrounding the cell tip. go-plus.json 'plasma membrane, cell tip' http://purl.obolibrary.org/obo/GO_0031520 GO:0031521 biolink:CellularComponent spitzenkorper Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments. go-plus.json http://purl.obolibrary.org/obo/GO_0031521 CHEBI:136220 biolink:ChemicalSubstance phosphatidylglycerol 32:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136220 GO:0031517 biolink:MolecularActivity red light photoreceptor activity The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation. go-plus.json http://purl.obolibrary.org/obo/GO_0031517 GO:0031518 biolink:CellularComponent CBF3 complex A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p. go-plus.json http://purl.obolibrary.org/obo/GO_0031518 GO:0031515 biolink:CellularComponent tRNA (m1A) methyltransferase complex A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. go-plus.json http://purl.obolibrary.org/obo/GO_0031515 GO:0031516 biolink:MolecularActivity far-red light photoreceptor activity The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation. go-plus.json http://purl.obolibrary.org/obo/GO_0031516 GO:0031513 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031513 GO:0006579 biolink:BiologicalProcess amino-acid betaine catabolic process The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid. go-plus.json betaine degradation|betaine breakdown|betaine catabolic process|betaine catabolism http://purl.obolibrary.org/obo/GO_0006579 GO:0031514 biolink:CellularComponent motile cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. go-plus.json motile primary cilium|microtubule-based flagellum|motile secondary cilium|motile cilia|motile primary cilia|nodal cilium http://purl.obolibrary.org/obo/GO_0031514 GO:0006577 biolink:BiologicalProcess amino-acid betaine metabolic process The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid. go-plus.json betaine metabolism|betaine metabolic process http://purl.obolibrary.org/obo/GO_0006577 GO:0031511 biolink:CellularComponent Mis6-Sim4 complex A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human. go-plus.json Mis6 centromere subcomplex|Mis6-Mal2-Sim4 centromere complex|Sim4 complex http://purl.obolibrary.org/obo/GO_0031511 GO:0031512 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031512 GO:0006578 biolink:BiologicalProcess amino-acid betaine biosynthetic process The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid. go-plus.json betaine anabolism|betaine synthesis|betaine formation|betaine biosynthesis|betaine biosynthetic process http://purl.obolibrary.org/obo/GO_0006578 GO:0006575 biolink:BiologicalProcess cellular modified amino acid metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. go-plus.json cellular amino acid derivative metabolism|modified amino acid metabolic process|cellular amino acid derivative metabolic process|modified amino acid metabolism|amino acid derivative metabolic process|cellular modified amino acid metabolism http://purl.obolibrary.org/obo/GO_0006575 GO:0006576 biolink:BiologicalProcess cellular biogenic amine metabolic process The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. go-plus.json biogenic amine metabolism http://purl.obolibrary.org/obo/GO_0006576 GO:0006573 biolink:BiologicalProcess valine metabolic process The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid. go-plus.json valine metabolism http://purl.obolibrary.org/obo/GO_0006573 GO:0006574 biolink:BiologicalProcess valine catabolic process The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid. MetaCyc:VALDEG-PWY go-plus.json valine catabolism|valine degradation|valine breakdown http://purl.obolibrary.org/obo/GO_0006574 GO:0006571 biolink:BiologicalProcess tyrosine biosynthetic process The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. go-plus.json tyrosine anabolism|tyrosine synthesis|tyrosine formation|tyrosine biosynthesis http://purl.obolibrary.org/obo/GO_0006571 GO:0006572 biolink:BiologicalProcess tyrosine catabolic process The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. go-plus.json tyrosine degradation|tyrosine breakdown|tyrosine catabolism http://purl.obolibrary.org/obo/GO_0006572 GO:0031519 biolink:CellularComponent PcG protein complex A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. go-plus.json Polycomb Group protein complex http://purl.obolibrary.org/obo/GO_0031519 goslim_pir GO:0006570 biolink:BiologicalProcess tyrosine metabolic process The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. Wikipedia:Tyrosine|UM-BBD_pathwayID:tyr go-plus.json tyrosine metabolism http://purl.obolibrary.org/obo/GO_0006570 CHEBI:136235 biolink:ChemicalSubstance phosphatidylinositol 36:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136235 CHEBI:136236 biolink:ChemicalSubstance phosphatidylinositol 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136236 CHEBI:136239 biolink:ChemicalSubstance phosphatidylinositol 38:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136239 GO:0031510 biolink:CellularComponent SUMO activating enzyme complex A conserved heterodimeric complex with SUMO activating enzyme activity. go-plus.json SAE|SUMO E1 activator enzyme complex http://purl.obolibrary.org/obo/GO_0031510 NCBITaxon:43738 biolink:OrganismalEntity Schizophora go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_43738 CHEBI:32829 biolink:ChemicalSubstance D-threonyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32829 PR:000007892 biolink:Protein glucagon receptor A glucagon-like receptor that is a translation product of the human GCGR gene or a 1:1 ortholog thereof. go-plus.json GL-R|GCGR http://purl.obolibrary.org/obo/PR_000007892 CHEBI:32822 biolink:ChemicalSubstance L-threoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32822 PR:000007893 biolink:Protein GTP cyclohydrolase 1 A protein that is a translation product of the human GCH1 gene or a 1:1 ortholog thereof. go-plus.json DYT5|GCH|GCH1|GTP cyclohydrolase I|GTP-CH-I http://purl.obolibrary.org/obo/PR_000007893 CHEBI:32823 biolink:ChemicalSubstance L-threonyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32823 NCBITaxon:43733 biolink:OrganismalEntity Muscomorpha go-plus.json Asilomorpha http://purl.obolibrary.org/obo/NCBITaxon_43733 CHEBI:32826 biolink:ChemicalSubstance D-allothreonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32826 CHEBI:32827 biolink:ChemicalSubstance D-threoninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32827 CHEBI:32828 biolink:ChemicalSubstance D-threoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32828 CHEBI:32820 biolink:ChemicalSubstance L-threoninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32820 CHEBI:91126 biolink:ChemicalSubstance 2-trans,4-trans-xanthoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_91126 chebi_ph7_3 CHEBI:91128 biolink:ChemicalSubstance 3-acetylchlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_91128 CHEBI:91121 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_91121 chebi_ph7_3 NCBITaxon:1355477 biolink:OrganismalEntity Bradyrhizobium diazoefficiens go-plus.json Bradyrhizobium japonicum group Ia http://purl.obolibrary.org/obo/NCBITaxon_1355477 CHEBI:32832 biolink:ChemicalSubstance threoninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32832 CHEBI:32833 biolink:ChemicalSubstance threoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32833 CHEBI:32835 biolink:ChemicalSubstance threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32835 CHEBI:32836 biolink:ChemicalSubstance L-serinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32836 CHEBI:32837 biolink:ChemicalSubstance L-serinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32837 CHEBI:91118 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_91118 chebi_ph7_3 CHEBI:91119 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_91119 chebi_ph7_3 CHEBI:32807 biolink:ChemicalSubstance o-orsellinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32807 CHEBI:32808 biolink:ChemicalSubstance (Z)-5-oxohex-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32808 CHEBI:91140 biolink:ChemicalSubstance 15(R)-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91140 CHEBI:32809 biolink:ChemicalSubstance 3-hydroxy-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32809 CHEBI:32800 biolink:ChemicalSubstance (S)-mandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32800 CHEBI:32802 biolink:ChemicalSubstance (S)-4-hydroxymandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32802 CHEBI:32803 biolink:ChemicalSubstance (R)-4-hydroxymandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32803 CHEBI:32804 biolink:ChemicalSubstance 4-hydroxymandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32804 chebi_ph7_3 CHEBI:32805 biolink:ChemicalSubstance cis-aconitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32805 CHEBI:32806 biolink:ChemicalSubstance trans-aconitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32806 CHEBI:17209 biolink:ChemicalSubstance dihydrosanguinarine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17209 chebi_ph7_3 CHEBI:17206 biolink:ChemicalSubstance 9,11alpha-epoxypregn-4-ene-3,20-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17206 chebi_ph7_3 CHEBI:17207 biolink:ChemicalSubstance 2-methylideneglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17207 CHEBI:17204 biolink:ChemicalSubstance 4,5-dioxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17204 OIO:hasOBONamespace biolink:OntologyClass has_obo_namespace go-plus.json http://www.geneontology.org/formats/oboInOwl#hasOBONamespace CHEBI:17202 biolink:ChemicalSubstance IMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17202 CHEBI:17203 biolink:ChemicalSubstance L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17203 CHEBI:17200 biolink:ChemicalSubstance UDP-alpha-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17200 CHEBI:17201 biolink:ChemicalSubstance glycylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17201 CHEBI:91143 biolink:ChemicalSubstance (3S,5R,6S)-beta-cryptoxanthin 5,6-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_91143 chebi_ph7_3 CHEBI:32818 biolink:ChemicalSubstance p-coumaroylagmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32818 CHEBI:32819 biolink:ChemicalSubstance L-2-amino-4-chloropent-4-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32819 CHEBI:91130 biolink:ChemicalSubstance 2-trans-(+)-abscisic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_91130 chebi_ph7_3 UBERON:0017261 biolink:AnatomicalEntity intertarsal sesamoid A sesamoid element that is part of a tarsal skeleton. go-plus.json tarsal sesamoid http://purl.obolibrary.org/obo/UBERON_0017261 CHEBI:32810 biolink:ChemicalSubstance 3-hydroxy-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32810 chebi_ph7_3 CHEBI:32811 biolink:ChemicalSubstance 4-hydroxy-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32811 CHEBI:32812 biolink:ChemicalSubstance 4-hydroxy-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32812 chebi_ph7_3 CHEBI:32813 biolink:ChemicalSubstance N-amidino-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32813 CHEBI:32814 biolink:ChemicalSubstance N-carbamoyl-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32814 chebi_ph7_3 CHEBI:32815 biolink:ChemicalSubstance enol-phenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32815 CHEBI:32816 biolink:ChemicalSubstance pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32816 CHEBI:32817 biolink:ChemicalSubstance keto-3-deoxy-D-manno-octulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32817 CHEBI:91136 biolink:ChemicalSubstance 5(S),11(R)-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91136 CHEBI:91137 biolink:ChemicalSubstance 17(R)-HDoHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91137 CHEBI:91138 biolink:ChemicalSubstance 5(S),15(R)-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91138 CHEBI:91139 biolink:ChemicalSubstance elastin-laminin receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_91139 CHEBI:91132 biolink:ChemicalSubstance 18(R)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91132 CHEBI:91133 biolink:ChemicalSubstance prostaglandin H1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_91133 CHEBI:91134 biolink:ChemicalSubstance L-erythrulose 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91134 CHEBI:91135 biolink:ChemicalSubstance 19-hydroxyprostaglandin H1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_91135 CHEBI:91165 biolink:ChemicalSubstance capsanthin 5,6-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_91165 chebi_ph7_3 CHEBI:91180 biolink:ChemicalSubstance (R)-3-(indol-3-yl)-2-oxobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91180 chebi_ph7_3 CHEBI:91181 biolink:ChemicalSubstance 2-phosphinomethylmalate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91181 chebi_ph7_3 CHEBI:91175 biolink:ChemicalSubstance hypusine(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_91175 chebi_ph7_3 NCBITaxon:43746 biolink:OrganismalEntity Ephydroidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_43746 GO:0031599 biolink:CellularComponent obsolete ER proteasome regulatory particle OBSOLETE. The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031599 NCBITaxon:43741 biolink:OrganismalEntity Acalyptratae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_43741 UBERON:4100000 biolink:AnatomicalEntity skeletal element projection Anatomical projection that is composed of bone or cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_4100000 GO:0031590 biolink:BiologicalProcess wybutosine metabolic process The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. go-plus.json wybutosine metabolism|yW metabolism|yW metabolic process http://purl.obolibrary.org/obo/GO_0031590 GO:0031597 biolink:CellularComponent cytosolic proteasome complex A proteasome complex found in the cytosol of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031597 GO:0031598 biolink:CellularComponent nuclear proteasome regulatory particle The regulatory subcomplex of a proteasome located in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031598 GO:0031595 biolink:CellularComponent nuclear proteasome complex A proteasome found in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031595 GO:0031596 biolink:CellularComponent obsolete ER proteasome complex OBSOLETE. A proteasome found in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031596 GO:0031593 biolink:MolecularActivity polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0031593 CHEBI:91176 biolink:ChemicalSubstance deoxyhypusine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_91176 GO:0031594 biolink:CellularComponent neuromuscular junction The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. Wikipedia:Neuromuscular_junction|NIF_Subcellular:sao1124888485 go-plus.json motor endplate|NMJ http://purl.obolibrary.org/obo/GO_0031594 CHEBI:91177 biolink:ChemicalSubstance maltose 6'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91177 chebi_ph7_3 CHEBI:91178 biolink:ChemicalSubstance N-demethylindolmycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91178 chebi_ph7_3 GO:0031591 biolink:BiologicalProcess wybutosine biosynthetic process The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. go-plus.json yW biosynthesis|yW biosynthetic process http://purl.obolibrary.org/obo/GO_0031591 CHEBI:91179 biolink:ChemicalSubstance indolmycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91179 chebi_ph7_3 GO:0031592 biolink:CellularComponent centrosomal corona An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin. go-plus.json http://purl.obolibrary.org/obo/GO_0031592 CHEBI:17150 biolink:ChemicalSubstance 2-phosphoglycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17150 CHEBI:17151 biolink:ChemicalSubstance xylitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17151 chebi_ph7_3 CHEBI:42115 biolink:ChemicalSubstance 3-deoxy-alpha-D-manno-2-octulosonic acid 8-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_42115 CHEBI:32789 biolink:ChemicalSubstance tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32789 CHEBI:42112 biolink:ChemicalSubstance 1-(2-deoxy-5-O-phosphono-beta-L-ribofuranosyl)thymine go-plus.json http://purl.obolibrary.org/obo/CHEBI_42112 CHEBI:42111 biolink:ChemicalSubstance (R)-lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42111 CHEBI:32784 biolink:ChemicalSubstance tyrosinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32784 CHEBI:32785 biolink:ChemicalSubstance tyrosinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32785 CHEBI:32786 biolink:ChemicalSubstance tyrosinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32786 CHEBI:17149 biolink:ChemicalSubstance N-acetyl-beta-D-glycosaminyl glycopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17149 CHEBI:17147 biolink:ChemicalSubstance 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17147 chebi_ph7_3 CHEBI:17148 biolink:ChemicalSubstance putrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17148 CHEBI:17146 biolink:ChemicalSubstance anhydrotetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17146 CHEBI:17143 biolink:ChemicalSubstance 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17143 chebi_ph7_3 CHEBI:17144 biolink:ChemicalSubstance 2-(3-amino-3-carboxypropyl)-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17144 PR:000007806 biolink:Protein galanin A protein that is a translation product of the human GAL gene or a 1:1 ortholog thereof. go-plus.json GAL1|GALN|GAL|GLNN http://purl.obolibrary.org/obo/PR_000007806 CHEBI:17141 biolink:ChemicalSubstance cysteamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17141 CHEBI:17142 biolink:ChemicalSubstance 5-formyl-2-hydroxyhepta-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17142 CHEBI:17140 biolink:ChemicalSubstance D-xylulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17140 chebi_ph7_3 CHEBI:42101 biolink:ChemicalSubstance D-norleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_42101 CHEBI:32796 biolink:ChemicalSubstance (R)-2-hydroxyglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32796 CHEBI:17138 biolink:ChemicalSubstance glyceraldehyde 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17138 CHEBI:32797 biolink:ChemicalSubstance (S)-2-hydroxyglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32797 CHEBI:17139 biolink:ChemicalSubstance 6-O-sulfo-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->3)-1-O-alkyl-2-O-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17139 CHEBI:32798 biolink:ChemicalSubstance 9-cis,11-trans-octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32798 CHEBI:17136 biolink:ChemicalSubstance 2,8-dihydroxy-1,4-naphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17136 CHEBI:17137 biolink:ChemicalSubstance hydrogensulfite go-plus.json http://purl.obolibrary.org/obo/CHEBI_17137 CHEBI:17134 biolink:ChemicalSubstance octopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17134 CHEBI:17135 biolink:ChemicalSubstance long-chain fatty alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17135 chebi_ph7_3 CHEBI:17132 biolink:ChemicalSubstance diethyl (2R,3R)-2-hydroxy-3-methylsuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17132 chebi_ph7_3 CHEBI:17133 biolink:ChemicalSubstance deoxylimonoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17133 CHEBI:17130 biolink:ChemicalSubstance 10-oxocapric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17130 CHEBI:17131 biolink:ChemicalSubstance (3,5-diiodo-4-hydroxyphenyl)pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17131 CHEBI:17172 biolink:ChemicalSubstance 2'-deoxyguanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17172 chebi_ph7_3 CHEBI:17173 biolink:ChemicalSubstance D-ribulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17173 chebi_ph7_3 CHEBI:17170 biolink:ChemicalSubstance dimethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17170 UBERON:0007997 biolink:AnatomicalEntity sesamoid bone of manus A sesamoid bone that is part of a manus. go-plus.json sesamoid bone of hand http://purl.obolibrary.org/obo/UBERON_0007997 CHEBI:32760 biolink:ChemicalSubstance L-tyrosinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32760 CHEBI:32761 biolink:ChemicalSubstance L-tyrosinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32761 CHEBI:32762 biolink:ChemicalSubstance L-tyrosinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32762 CHEBI:32764 biolink:ChemicalSubstance L-tyrosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32764 CHEBI:17169 biolink:ChemicalSubstance benzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17169 chebi_ph7_3 CHEBI:17167 biolink:ChemicalSubstance (R)-lactaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17167 chebi_ph7_3 CHEBI:17168 biolink:ChemicalSubstance 5alpha-cholest-7-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17168 chebi_ph7_3 CHEBI:17165 biolink:ChemicalSubstance Photinus luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17165 CHEBI:17166 biolink:ChemicalSubstance N-methylputrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17166 CHEBI:17163 biolink:ChemicalSubstance S-methyl D-thioglycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17163 chebi_ph7_3 CHEBI:17164 biolink:ChemicalSubstance stachyose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17164 chebi_ph7_3 CHEBI:17161 biolink:ChemicalSubstance O-demethylpuromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17161 CHEBI:17162 biolink:ChemicalSubstance 2-oxooctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17162 chebi_ph7_3 CHEBI:17160 biolink:ChemicalSubstance 17alpha-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17160 chebi_ph7_3 CHEBI:32778 biolink:ChemicalSubstance D-tyrosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32778 NCBITaxon:43786 biolink:OrganismalEntity Culicomorpha go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_43786 CHEBI:32773 biolink:ChemicalSubstance D-tyrosinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32773 CHEBI:32774 biolink:ChemicalSubstance D-tyrosinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32774 CHEBI:32775 biolink:ChemicalSubstance D-tyrosinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32775 CHEBI:17158 biolink:ChemicalSubstance methylglyoxal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17158 chebi_ph7_3 CHEBI:17159 biolink:ChemicalSubstance (R)-carnitinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17159 chebi_ph7_3 CHEBI:17156 biolink:ChemicalSubstance 1D-3-amino-1-guanidino-1,3-dideoxy-scyllo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17156 CHEBI:17157 biolink:ChemicalSubstance trans,trans-2,3,4,5-tetradehydroacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_17157 CHEBI:17154 biolink:ChemicalSubstance nicotinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17154 chebi_ph7_3 CHEBI:17155 biolink:ChemicalSubstance flavonol 3-O-(6-O-malonyl-beta-D-glucoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17155 CHEBI:17152 biolink:ChemicalSubstance phosphatidyl-N,N-dimethylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17152 CHEBI:17153 biolink:ChemicalSubstance propanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17153 chebi_ph7_3 CHEBI:32744 biolink:ChemicalSubstance L-selenocysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32744 CHEBI:32747 biolink:ChemicalSubstance D-selenocysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32747 CHEBI:17109 biolink:ChemicalSubstance 7,8-dihydro-7,8-dihydroxykynurenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17109 CHEBI:17108 biolink:ChemicalSubstance D-arabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17108 CHEBI:17105 biolink:ChemicalSubstance 4-maleylacetoacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17105 chebi_ph7_3 CHEBI:32742 biolink:ChemicalSubstance L-selenocysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32742 CHEBI:32743 biolink:ChemicalSubstance L-selenocysteinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32743 CHEBI:17106 biolink:ChemicalSubstance 1-alkyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17106 CHEBI:17103 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide(d18:1(4E)) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17103 chebi_ph7_3 CHEBI:17104 biolink:ChemicalSubstance 6-hydroxyprotopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17104 chebi_ph7_3 CHEBI:17101 biolink:ChemicalSubstance macarpine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17101 chebi_ph7_3 CHEBI:17102 biolink:ChemicalSubstance phosphoramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17102 CHEBI:17100 biolink:ChemicalSubstance L-arabinono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17100 chebi_ph7_3 CHEBI:175901 biolink:ChemicalSubstance gemcitabine go-plus.json http://purl.obolibrary.org/obo/CHEBI_175901 chebi_ph7_3 PR:000007856 biolink:Protein gastrin A protein that is a translation product of the human GAST gene or a 1:1 ortholog thereof. go-plus.json GAST|GAS http://purl.obolibrary.org/obo/PR_000007856 CHEBI:32750 biolink:ChemicalSubstance D-selenocysteinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32750 CHEBI:32751 biolink:ChemicalSubstance D-selenocysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32751 CHEBI:32752 biolink:ChemicalSubstance selenocysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32752 CHEBI:32753 biolink:ChemicalSubstance selenocysteinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32753 CHEBI:32754 biolink:ChemicalSubstance selenocysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32754 CHEBI:32722 biolink:ChemicalSubstance glycyl radical residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32722 chebi_ph7_3 CHEBI:32727 biolink:ChemicalSubstance tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32727 CHEBI:32728 biolink:ChemicalSubstance tryptophanium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32728 CHEBI:17129 biolink:ChemicalSubstance (S)-scoulerine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17129 chebi_ph7_3 CHEBI:17127 biolink:ChemicalSubstance glucotropeolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17127 CHEBI:17128 biolink:ChemicalSubstance adipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17128 chebi_ph7_3 CHEBI:32721 biolink:ChemicalSubstance glycyl radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_32721 CHEBI:17125 biolink:ChemicalSubstance 6-acetamido-3-aminohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17125 CHEBI:17126 biolink:ChemicalSubstance carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17126 chebi_ph7_3 CHEBI:17123 biolink:ChemicalSubstance 2-aminoacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17123 CHEBI:17121 biolink:ChemicalSubstance oxomalonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17121 chebi_ph7_3 CHEBI:17122 biolink:ChemicalSubstance aldehydo-N-acetyl-D-mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17122 chebi_ph7_3 CHEBI:17120 biolink:ChemicalSubstance hexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17120 chebi_ph7_3 CHEBI:17118 biolink:ChemicalSubstance aldehydo-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17118 chebi_ph7_3 CHEBI:17119 biolink:ChemicalSubstance fMet-tRNA(fMet) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17119 CHEBI:17117 biolink:ChemicalSubstance 5-dehydro-4-deoxy-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17117 chebi_ph7_3 CHEBI:17114 biolink:ChemicalSubstance N(5)-formyl-5,6,7,8-tetrahydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17114 CHEBI:17115 biolink:ChemicalSubstance L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17115 CHEBI:17113 biolink:ChemicalSubstance erythritol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17113 chebi_ph7_3 CHEBI:17110 biolink:ChemicalSubstance 1-guanidino-1-deoxy-scyllo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17110 CHEBI:17111 biolink:ChemicalSubstance 5-O-phosphono-alpha-D-ribofuranosyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17111 GO:0031506 biolink:BiologicalProcess cell wall glycoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues. go-plus.json cell wall glycoprotein anabolism|cell wall glycoprotein biosynthesis|cell wall glycoprotein synthesis|cell wall glycoprotein formation http://purl.obolibrary.org/obo/GO_0031506 GO:0031507 biolink:BiologicalProcess heterochromatin assembly An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation. go-plus.json establishment of heterochromatin architecture involved in chromatin silencing at pericentric region|establishment of heterochromatin architecture|chromatin-mediated silencing|transcriptional gene silencing|TGS|heterochromatin formation involved in chromatin silencing at centromere outer repeat region|heterochromatin assembly involved in chromatin silencing at pericentric region|heterochromatin formation|heterochromatin assembly involved in chromatin silencing|heterochromatin formation involved in chromatin silencing at pericentric region|heterochromatic silencing|establishment of heterochromatic silencing|heterochromatin formation involved in chromatin silencing|heterochromatin assembly involved in chromatin silencing at centromere outer repeat region|chromatin silencing|establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region|heterochromatin maintenance|establishment of chromatin silencing http://purl.obolibrary.org/obo/GO_0031507 GO:0006548 biolink:BiologicalProcess histidine catabolic process The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. go-plus.json histidine catabolism|histidine degradation|histidine breakdown http://purl.obolibrary.org/obo/GO_0006548 GO:0031504 biolink:BiologicalProcess peptidoglycan-based cell wall organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall. go-plus.json peptidoglycan-based cell wall organization and biogenesis|peptidoglycan-based cell wall organisation http://purl.obolibrary.org/obo/GO_0031504 GO:0006549 biolink:BiologicalProcess isoleucine metabolic process The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. go-plus.json isoleucine metabolism http://purl.obolibrary.org/obo/GO_0006549 GO:0031505 biolink:BiologicalProcess fungal-type cell wall organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. go-plus.json beta-glucan-containing cell wall organization and biogenesis|chitin- and beta-glucan-containing cell wall organization and biogenesis|fungal-type cell wall organization and biogenesis|chitin- and beta-glucan-containing cell wall organisation|chitin-containing cell wall organization and biogenesis http://purl.obolibrary.org/obo/GO_0031505 GO:0031502 biolink:CellularComponent dolichyl-phosphate-mannose-protein mannosyltransferase complex A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies. go-plus.json PMT family mannosyltransferase complex|protein O-mannosyltransferase complex http://purl.obolibrary.org/obo/GO_0031502 GO:0006546 biolink:BiologicalProcess glycine catabolic process The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid. go-plus.json glycine catabolism|glycine degradation|glycine breakdown http://purl.obolibrary.org/obo/GO_0006546 CHEBI:42191 biolink:ChemicalSubstance ethylenediaminetetraacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42191 GO:0031503 biolink:BiologicalProcess protein-containing complex localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of protein complex localization|protein complex localisation|protein complex localization http://purl.obolibrary.org/obo/GO_0031503 GO:0006547 biolink:BiologicalProcess histidine metabolic process The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. Wikipedia:Histidine go-plus.json histidine metabolism http://purl.obolibrary.org/obo/GO_0006547 GO:0031500 biolink:CellularComponent Tea1 cell-end complex A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0031500 GO:0006544 biolink:BiologicalProcess glycine metabolic process The chemical reactions and pathways involving glycine, aminoethanoic acid. go-plus.json glycine metabolism http://purl.obolibrary.org/obo/GO_0006544 GO:0006545 biolink:BiologicalProcess glycine biosynthetic process The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid. MetaCyc:GLYCINE-SYN2-PWY go-plus.json glycine anabolism|glycine synthesis|glycine formation|glycine biosynthesis http://purl.obolibrary.org/obo/GO_0006545 GO:0031501 biolink:CellularComponent mannosyltransferase complex A complex that posseses mannosyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0031501 goslim_pir GO:0006542 biolink:BiologicalProcess glutamine biosynthetic process The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid. MetaCyc:GLNSYN-PWY go-plus.json glutamine anabolism|glutamine synthesis|glutamine formation|glutamine biosynthesis http://purl.obolibrary.org/obo/GO_0006542 GO:0006543 biolink:BiologicalProcess glutamine catabolic process The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid. go-plus.json glutamine catabolism|glutamine degradation|glutamine breakdown http://purl.obolibrary.org/obo/GO_0006543 GO:0006540 biolink:BiologicalProcess glutamate decarboxylation to succinate The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes. MetaCyc:GLUDEG-I-PWY|MetaCyc:PWY3O-210|MetaCyc:PWY-4321 go-plus.json glutamate degradation via GABA|degradation of glutamate to succinate through GABA|4-aminobutyrate shunt|GABA shunt|glutamate degradation via 4-aminobutyrate|gamma-aminobutyrate shunt http://purl.obolibrary.org/obo/GO_0006540 GO:0006541 biolink:BiologicalProcess glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. go-plus.json glutamine metabolism http://purl.obolibrary.org/obo/GO_0006541 GO:0031508 biolink:BiologicalProcess pericentric heterochromatin assembly The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA. go-plus.json centromeric heterochromatin formation|chromatin silencing at centromere outer repeat region|centromere chromatin silencing|centric heterochromatin formation|heterochromatic silencing at centromere|centromeric heterochromatin biosynthesis|chromatin silencing at pericentric region|centromeric silencing|chromatin silencing at centromere http://purl.obolibrary.org/obo/GO_0031508 GO:0031509 biolink:BiologicalProcess subtelomeric heterochromatin assembly The assembly of chromatin into heterochromatin at the subtelomeric region, resulting in a chromatin conformation refractory to transcription. go-plus.json subtelomeric silencing|subtelomere chromatin silencing|heterochromatic silencing at telomere|regulation of subtelomeric heterochromatin assembly|regulation of chromatin silencing at telomere|Telomere Position Effect|telomeric silencing|chromatin silencing at telomere|chromatin silencing at subtelomere|telomeric heterochromatin assembly|establishment of chromatin silencing at telomere|telomeric heterochromatin formation|heterochromatic silencing at subtelomere|telomere chromatin silencing http://purl.obolibrary.org/obo/GO_0031509 GO:0006559 biolink:BiologicalProcess L-phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid. go-plus.json L-phenylalanine catabolism|L-phenylalanine degradation|L-phenylalanine breakdown|phenylalanine catabolism|phenylalanine catabolic process http://purl.obolibrary.org/obo/GO_0006559 GO:0006557 biolink:BiologicalProcess S-adenosylmethioninamine biosynthetic process The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt. go-plus.json S-adenosylmethioninamine biosynthesis|S-adenosylmethioninamine anabolism|S-adenosylmethioninamine synthesis|S-adenosylmethioninamine formation http://purl.obolibrary.org/obo/GO_0006557 GO:0006558 biolink:BiologicalProcess L-phenylalanine metabolic process The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid. go-plus.json L-phenylalanine metabolism|phenylalanine metabolic process|phenylalanine metabolism http://purl.obolibrary.org/obo/GO_0006558 GO:0006555 biolink:BiologicalProcess methionine metabolic process The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. UM-BBD_pathwayID:met go-plus.json methionine and threonine metabolic process|methionine and threonine metabolism|methionine metabolism http://purl.obolibrary.org/obo/GO_0006555 GO:0006556 biolink:BiologicalProcess S-adenosylmethionine biosynthetic process The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. MetaCyc:SAM-PWY go-plus.json S-adenosylmethionine anabolism|S-adenosylmethionine synthesis|S-adenosylmethionine formation|SAM biosynthetic process|S-adenosylmethionine biosynthesis|S-adenosyl methionine biosynthetic process|S-adenosyl methionine biosynthesis http://purl.obolibrary.org/obo/GO_0006556 GO:0006553 biolink:BiologicalProcess lysine metabolic process The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. Wikipedia:Lysine go-plus.json lysine metabolism http://purl.obolibrary.org/obo/GO_0006553 GO:0006554 biolink:BiologicalProcess lysine catabolic process The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid. go-plus.json lysine breakdown|lysine catabolism|lysine degradation http://purl.obolibrary.org/obo/GO_0006554 GO:0006551 biolink:BiologicalProcess leucine metabolic process The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid. go-plus.json leucine metabolism http://purl.obolibrary.org/obo/GO_0006551 GO:0006552 biolink:BiologicalProcess leucine catabolic process The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid. MetaCyc:LEU-DEG2-PWY go-plus.json leucine breakdown|leucine catabolism|leucine degradation http://purl.obolibrary.org/obo/GO_0006552 GO:0006550 biolink:BiologicalProcess isoleucine catabolic process The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. MetaCyc:ILEUDEG-PWY go-plus.json isoleucine degradation|isoleucine breakdown|isoleucine catabolism http://purl.obolibrary.org/obo/GO_0006550 CHEBI:136335 biolink:ChemicalSubstance 13-(octadecanoyloxy)octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136335 chebi_ph7_3 CHEBI:136330 biolink:ChemicalSubstance 12-(octadecanoyloxy)octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136330 chebi_ph7_3 GO:0006528 biolink:BiologicalProcess asparagine metabolic process The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid. MetaCyc:ASPARAGINESYN-PWY go-plus.json asparagine metabolism http://purl.obolibrary.org/obo/GO_0006528 BSPO:0001101 biolink:OntologyClass in_deep_part_of X superficial_part_of Y <=> if Y is subdivided into two superficial and deep portions, X is part_of the deep portion. BSPO:0001101 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001101 GO:0006529 biolink:BiologicalProcess asparagine biosynthetic process The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid. go-plus.json asparagine anabolism|asparagine biosynthesis|asparagine synthesis|asparagine formation http://purl.obolibrary.org/obo/GO_0006529 GO:0006526 biolink:BiologicalProcess arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. MetaCyc:ARGSYN-PWY|MetaCyc:ARGSYNBSUB-PWY|MetaCyc:ARGININE-SYN4-PWY go-plus.json arginine biosynthesis|arginine anabolism|arginine synthesis|arginine formation http://purl.obolibrary.org/obo/GO_0006526 GO:0006527 biolink:BiologicalProcess arginine catabolic process The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. go-plus.json arginine degradation|arginine catabolism|arginine breakdown http://purl.obolibrary.org/obo/GO_0006527 BSPO:0001100 biolink:OntologyClass in_superficial_part_of X superficial_part_of Y <=> if Y is subdivided into two superficial and deep portions, X is part_of the superficial portion. BSPO:0001100 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001100 GO:0006524 biolink:BiologicalProcess alanine catabolic process The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid. go-plus.json alanine degradation|alanine breakdown|alanine catabolism http://purl.obolibrary.org/obo/GO_0006524 BSPO:0001106 biolink:OntologyClass proximalmost_part_of X proximalmost_part_of Y <=> X is part_of Y and X is adjacent_to the proximal boundary of Y BSPO:0001106 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001106 GO:0006525 biolink:BiologicalProcess arginine metabolic process The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. Wikipedia:Arginine go-plus.json arginine metabolism http://purl.obolibrary.org/obo/GO_0006525 GO:0006522 biolink:BiologicalProcess alanine metabolic process The chemical reactions and pathways involving alanine, 2-aminopropanoic acid. go-plus.json alanine metabolism http://purl.obolibrary.org/obo/GO_0006522 GO:0006523 biolink:BiologicalProcess alanine biosynthetic process The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid. go-plus.json alanine biosynthesis|alanine anabolism|alanine synthesis|alanine formation http://purl.obolibrary.org/obo/GO_0006523 GO:0006520 biolink:BiologicalProcess cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells. go-plus.json amino acid metabolic process|cellular amino acid and derivative metabolic process|amino acid and derivative metabolism|cellular amino acid metabolism http://purl.obolibrary.org/obo/GO_0006520 goslim_yeast|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl GO:0006521 biolink:BiologicalProcess regulation of cellular amino acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. go-plus.json regulation of amino acid metabolism http://purl.obolibrary.org/obo/GO_0006521 BSPO:0001107 biolink:OntologyClass immediately_deep_to This relation holds when both the deep_to and ajdacent_to relationship similarly hold. BSPO:0001107 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001107 CHEBI:136309 biolink:ChemicalSubstance 9-[(9Z)-hexadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136309 chebi_ph7_3 BSPO:0001108 biolink:OntologyClass distalmost_part_of X distalmost_part_of Y <=> X is part_of Y and X is adjacent_to the distal boundary of Y BSPO:0001108 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001108 CHEBI:136303 biolink:ChemicalSubstance 13-[(9Z)-octadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136303 chebi_ph7_3 CHEBI:136304 biolink:ChemicalSubstance 13-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136304 chebi_ph7_3 CHEBI:136302 biolink:ChemicalSubstance 12-[(9Z)-octadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136302 chebi_ph7_3 UBERON:0007914 biolink:AnatomicalEntity bone of craniocervical region A bone that is part of a craniocervical region. go-plus.json head or neck bone|cranial bone http://purl.obolibrary.org/obo/UBERON_0007914 GO:0006539 biolink:BiologicalProcess glutamate catabolic process via 2-oxoglutarate The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate. MetaCyc:P162-PWY go-plus.json glutamate breakdown via 2-oxoglutarate|glutamate degradation via 2-oxoglutarate|glutamate catabolic process via 2-ketoglutarate|glutamate catabolic process via alpha-oxoglutarate|glutamate catabolism via alpha-ketoglutarate|glutamate catabolism via alpha-oxoglutarate|glutamate catabolism via 2-ketoglutarate|glutamate catabolic process via alpha-ketoglutarate http://purl.obolibrary.org/obo/GO_0006539 BSPO:0001113 biolink:OntologyClass preaxialmost_part_of BSPO:0001113 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001113 GO:0006537 biolink:BiologicalProcess glutamate biosynthetic process The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. go-plus.json glutamate biosynthesis, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamate anabolism|glutamic acid biosynthetic process|glutamic acid biosynthesis|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate synthesis|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate formation|glutamate biosynthesis http://purl.obolibrary.org/obo/GO_0006537 GO:0006538 biolink:BiologicalProcess glutamate catabolic process The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. go-plus.json glutamic acid catabolism|glutamic acid catabolic process|glutamate catabolism|glutamate deamidation|glutamate degradation|glutamate breakdown http://purl.obolibrary.org/obo/GO_0006538 GO:0006535 biolink:BiologicalProcess cysteine biosynthetic process from serine The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine. MetaCyc:CYSTSYN-PWY go-plus.json cysteine anabolism from serine|cysteine synthesis from serine|cysteine formation from serine http://purl.obolibrary.org/obo/GO_0006535 GO:0006536 biolink:BiologicalProcess glutamate metabolic process The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. Wikipedia:Glutamic_acid go-plus.json glutamic acid metabolism|glutamic acid metabolic process|glutamate metabolism http://purl.obolibrary.org/obo/GO_0006536 GO:0006533 biolink:BiologicalProcess aspartate catabolic process The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. go-plus.json aspartate degradation|aspartate breakdown|aspartate catabolism http://purl.obolibrary.org/obo/GO_0006533 BSPO:0001115 biolink:OntologyClass postaxialmost_part_of BSPO:0001115 go-plus.json http://purl.obolibrary.org/obo/BSPO_0001115 GO:0006534 biolink:BiologicalProcess cysteine metabolic process The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid. Wikipedia:Cysteine_metabolism go-plus.json cysteine metabolism http://purl.obolibrary.org/obo/GO_0006534 GO:0006531 biolink:BiologicalProcess aspartate metabolic process The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. go-plus.json aspartate metabolism http://purl.obolibrary.org/obo/GO_0006531 GO:0006532 biolink:BiologicalProcess aspartate biosynthetic process The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. go-plus.json aspartate biosynthesis|aspartate formation|aspartate anabolism|aspartate synthesis http://purl.obolibrary.org/obo/GO_0006532 GO:0006530 biolink:BiologicalProcess asparagine catabolic process The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid. go-plus.json asparagine degradation|asparagine breakdown|asparagine catabolism http://purl.obolibrary.org/obo/GO_0006530 CHEBI:42164 biolink:ChemicalSubstance 3-ammonio-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_42164 CHEBI:136315 biolink:ChemicalSubstance 13-[(9Z)-hexadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136315 chebi_ph7_3 CHEBI:136312 biolink:ChemicalSubstance 12-[(9Z)-hexadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136312 chebi_ph7_3 NCBITaxon:100226 biolink:OrganismalEntity Streptomyces coelicolor A3(2) go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_100226 GO:0006506 biolink:BiologicalProcess GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. go-plus.json GPI anchor anabolism|GPI anchor synthesis|GPI anchor formation|glycosylphosphatidylinositol biosynthetic process|glycosylphosphatidylinositol biosynthesis|GPI/GSI anchor biosynthetic process|GPI/GSI anchor biosynthesis|GPI anchor biosynthesis http://purl.obolibrary.org/obo/GO_0006506 CHEBI:17194 biolink:ChemicalSubstance bromochloromethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_17194 chebi_ph7_3 GO:0006507 biolink:BiologicalProcess GPI anchor release The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0006507 CHEBI:17195 biolink:ChemicalSubstance thiomorpholine-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17195 GO:0006504 biolink:BiologicalProcess obsolete C-terminal protein geranylgeranylation OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein. go-plus.json C-terminal protein geranylgeranylation http://purl.obolibrary.org/obo/GO_0006504 CHEBI:17192 biolink:ChemicalSubstance 3,5-dibromo-4-hydroxybenzonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_17192 GO:0006505 biolink:BiologicalProcess GPI anchor metabolic process The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain. go-plus.json GPI anchor metabolism|glycosylphosphatidylinositol metabolic process|GPI/GSI anchor metabolic process|glycosylphosphatidylinositol metabolism|GPI/GSI anchor metabolism http://purl.obolibrary.org/obo/GO_0006505 CHEBI:17193 biolink:ChemicalSubstance ADP-aldose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17193 GO:0006502 biolink:BiologicalProcess obsolete C-terminal protein prenylation OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added. go-plus.json C-terminal protein prenylation http://purl.obolibrary.org/obo/GO_0006502 GO:0006503 biolink:BiologicalProcess obsolete C-terminal protein farnesylation OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein. go-plus.json C-terminal protein farnesylation http://purl.obolibrary.org/obo/GO_0006503 CHEBI:17191 biolink:ChemicalSubstance L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17191 GO:0006500 biolink:BiologicalProcess N-terminal protein palmitoylation The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0006500 GO:0006501 biolink:BiologicalProcess C-terminal protein lipidation The covalent attachment of a lipid group to the carboxy-terminus of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0006501 CHEBI:42156 biolink:ChemicalSubstance 17-epiestriol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42156 chebi_ph7_3 CHEBI:17189 biolink:ChemicalSubstance 2,5-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17189 CHEBI:17187 biolink:ChemicalSubstance pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17187 chebi_ph7_3 CHEBI:17188 biolink:ChemicalSubstance nucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17188 CHEBI:4553 biolink:ChemicalSubstance dihydroanhydropodorhizol go-plus.json http://purl.obolibrary.org/obo/CHEBI_4553 chebi_ph7_3 GO:0006508 biolink:BiologicalProcess proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. Wikipedia:Proteolysis go-plus.json peptidolysis|ATP-dependent proteolysis http://purl.obolibrary.org/obo/GO_0006508 goslim_chembl|goslim_pir|goslim_metagenomics CHEBI:17185 biolink:ChemicalSubstance 2,3,5-trihydroxytoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17185 chebi_ph7_3 GO:0006509 biolink:BiologicalProcess membrane protein ectodomain proteolysis The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). go-plus.json receptor shedding|membrane protein solubilization|ectodomain cleavage|ectoderm shedding http://purl.obolibrary.org/obo/GO_0006509 CHEBI:17183 biolink:ChemicalSubstance sanguinarine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17183 chebi_ph7_3 GO:0006517 biolink:BiologicalProcess protein deglycosylation The removal of sugar residues from a glycosylated protein. go-plus.json glycoprotein deglycosylation http://purl.obolibrary.org/obo/GO_0006517 GO:0006518 biolink:BiologicalProcess peptide metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. go-plus.json peptide metabolism http://purl.obolibrary.org/obo/GO_0006518 goslim_pir CHEBI:17184 biolink:ChemicalSubstance chlordecone alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17184 chebi_ph7_3 GO:0006515 biolink:BiologicalProcess protein quality control for misfolded or incompletely synthesized proteins The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. go-plus.json misfolded or incompletely synthesized protein degradation|misfolded or incompletely synthesized protein breakdown|protein quality control by the ubiquitin-proteasome system|misfolded or incompletely synthesized protein catabolic process|misfolded or incompletely synthesized protein catabolism|protein quality control (PQC)|degradation of misfolded or incompletely synthesized proteins http://purl.obolibrary.org/obo/GO_0006515 CHEBI:17181 biolink:ChemicalSubstance 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17181 chebi_ph7_3 GO:0006516 biolink:BiologicalProcess glycoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. go-plus.json glycoprotein breakdown|glycoprotein catabolism|glycoprotein degradation http://purl.obolibrary.org/obo/GO_0006516 GO:0006513 biolink:BiologicalProcess protein monoubiquitination Addition of a single ubiquitin group to a protein. go-plus.json protein monoubiquitylation|protein monoubiquitinylation http://purl.obolibrary.org/obo/GO_0006513 GO:0006514 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006514 CHEBI:17180 biolink:ChemicalSubstance 3-hydroxypyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17180 chebi_ph7_3 GO:0006511 biolink:BiologicalProcess ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. go-plus.json protein ubiquitylation during ubiquitin-dependent protein catabolism|ubiquitin-dependent proteolysis|protein ubiquitinylation during ubiquitin-dependent protein catabolism|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitinylation during ubiquitin-dependent protein catabolic process|protein ubiquitylation during ubiquitin-dependent protein catabolic process|myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation|protein ubiquitination during ubiquitin-dependent protein catabolism|protein ubiquitination during ubiquitin-dependent protein degradation|myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|ubiquitin-dependent protein degradation|protein ubiquitination during ubiquitin-dependent protein breakdown|ubiquitin-dependent protein catabolism|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|protein ubiquitination during ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein breakdown|protein degradation tagging activity http://purl.obolibrary.org/obo/GO_0006511 GO:0006512 biolink:BiologicalProcess obsolete ubiquitin cycle OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein. go-plus.json ubiquitin cycle http://purl.obolibrary.org/obo/GO_0006512 CHEBI:42147 biolink:ChemicalSubstance (4R,5R)-1,2-dithiane-4,5-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42147 chebi_ph7_3 GO:0006510 biolink:BiologicalProcess obsolete ATP-dependent proteolysis OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP. go-plus.json ATP-dependent proteolysis|ATP-dependent peptidolysis http://purl.obolibrary.org/obo/GO_0006510 OBA:VT0002706 biolink:OntologyClass kidney size trait The size of a kidney. go-plus.json size of kidney http://purl.obolibrary.org/obo/OBA_VT0002706 CHEBI:17179 biolink:ChemicalSubstance taurolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17179 chebi_ph7_3 CHEBI:17176 biolink:ChemicalSubstance long-chain fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17176 chebi_ph7_3 CHEBI:17177 biolink:ChemicalSubstance cinnamyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17177 chebi_ph7_3 GO:0006519 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006519 CHEBI:17174 biolink:ChemicalSubstance heparosan N-sulfate L-iduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17174 CHEBI:17175 biolink:ChemicalSubstance guanidinoethyl methyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17175 CHEBI:17198 biolink:ChemicalSubstance dolichyl N-acetyl-alpha-D-glucosaminyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17198 CHEBI:17199 biolink:ChemicalSubstance 4,5-dihydroxyphthalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17199 CHEBI:17196 biolink:ChemicalSubstance L-asparagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17196 CHEBI:17197 biolink:ChemicalSubstance 1-alkylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17197 GO:0016070 biolink:BiologicalProcess RNA metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. go-plus.json RNA metabolism http://purl.obolibrary.org/obo/GO_0016070 goslim_agr|goslim_candida|goslim_pir|goslim_aspergillus|goslim_metagenomics GO:0016071 biolink:BiologicalProcess mRNA metabolic process The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. go-plus.json mRNA metabolism http://purl.obolibrary.org/obo/GO_0016071 goslim_drosophila|goslim_pombe GO:0016072 biolink:BiologicalProcess rRNA metabolic process The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. go-plus.json rRNA metabolism http://purl.obolibrary.org/obo/GO_0016072 goslim_drosophila GO:0065001 biolink:BiologicalProcess specification of axis polarity The pattern specification process in which the polarity of a body or organ axis is established and maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0065001 GO:0065004 biolink:BiologicalProcess protein-DNA complex assembly The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. go-plus.json DNA-protein complex assembly http://purl.obolibrary.org/obo/GO_0065004 GO:0065005 biolink:BiologicalProcess protein-lipid complex assembly The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex. go-plus.json http://purl.obolibrary.org/obo/GO_0065005 GO:0065002 biolink:BiologicalProcess intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore. go-plus.json intracellular protein transport across a membrane|intracellular membrane translocation of a protein|intracellular protein membrane transport http://purl.obolibrary.org/obo/GO_0065002 GO:0065003 biolink:BiologicalProcess protein-containing complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. go-plus.json macromolecular complex assembly|chaperone activity|protein complex formation|macromolecule complex assembly|protein complex assembly http://purl.obolibrary.org/obo/GO_0065003 goslim_pir|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl GO:0065008 biolink:BiologicalProcess regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. go-plus.json regulation of biological attribute|regulation of biological characteristic http://purl.obolibrary.org/obo/GO_0065008 goslim_pir GO:0065009 biolink:BiologicalProcess regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. go-plus.json regulation of a molecular function http://purl.obolibrary.org/obo/GO_0065009 gocheck_do_not_annotate|goslim_pir|goslim_plant GO:0065006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0065006 GO:0065007 biolink:BiologicalProcess biological regulation Any process that modulates a measurable attribute of any biological process, quality or function. go-plus.json regulation http://purl.obolibrary.org/obo/GO_0065007 gocheck_do_not_annotate|goslim_pir GO:0016066 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016066 GO:0016067 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016067 GO:0016068 biolink:BiologicalProcess type I hypersensitivity An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. Wikipedia:Type_I_hypersensitivity go-plus.json immediate hypersensitivity response http://purl.obolibrary.org/obo/GO_0016068 GO:0016069 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016069 GO:0016062 biolink:BiologicalProcess adaptation of rhodopsin mediated signaling The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation. go-plus.json adaptation of rhodopsin mediated signalling http://purl.obolibrary.org/obo/GO_0016062 GO:0016063 biolink:BiologicalProcess rhodopsin biosynthetic process The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas. go-plus.json rhodopsin biosynthesis|rhodopsin synthesis|rhodopsin formation|rhodopsin anabolism http://purl.obolibrary.org/obo/GO_0016063 CHEBI:91089 biolink:ChemicalSubstance CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91089 chebi_ph7_3 GO:0016064 biolink:BiologicalProcess immunoglobulin mediated immune response An immune response mediated by immunoglobulins, whether cell-bound or in solution. go-plus.json antibody-mediated immune response http://purl.obolibrary.org/obo/GO_0016064 GO:0016065 biolink:BiologicalProcess obsolete humoral defense mechanism (sensu Protostomia) OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317). go-plus.json humoral defense mechanism (sensu Protostomia)|humoral defence mechanism (sensu Protostomia) http://purl.obolibrary.org/obo/GO_0016065 GO:0016080 biolink:BiologicalProcess synaptic vesicle targeting The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces. go-plus.json http://purl.obolibrary.org/obo/GO_0016080 GO:0016081 biolink:BiologicalProcess synaptic vesicle docking The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process. go-plus.json synaptic vesicle docking involved in exocytosis|synaptic vesicle docking during exocytosis http://purl.obolibrary.org/obo/GO_0016081 goslim_synapse GO:0016082 biolink:BiologicalProcess synaptic vesicle priming A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0016082 goslim_synapse GO:0016083 biolink:BiologicalProcess obsolete synaptic vesicle fusion OBSOLETE. Fusion of the synaptic vesicle with the postsynaptic membrane. go-plus.json synaptic vesicle fusion http://purl.obolibrary.org/obo/GO_0016083 GO:0031698 biolink:MolecularActivity beta-2 adrenergic receptor binding Binding to a beta-2 adrenergic receptor. go-plus.json beta-2 adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031698 GO:0031699 biolink:MolecularActivity beta-3 adrenergic receptor binding Binding to a beta-3 adrenergic receptor. go-plus.json beta-3 adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031699 GO:0031696 biolink:MolecularActivity alpha-2C adrenergic receptor binding Binding to an alpha-2C adrenergic receptor. go-plus.json alpha-2C adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031696 GO:0016077 biolink:BiologicalProcess sno(s)RNA catabolic process The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. go-plus.json sno(s)RNA degradation|sno(s)RNA breakdown|sRNA catabolic process|sno(s)RNA catabolism|snoRNA catabolic process http://purl.obolibrary.org/obo/GO_0016077 GO:0016078 biolink:BiologicalProcess tRNA catabolic process The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. go-plus.json tRNA breakdown|tRNA catabolism|tRNA degradation http://purl.obolibrary.org/obo/GO_0016078 GO:0031697 biolink:MolecularActivity beta-1 adrenergic receptor binding Binding to a beta-1 adrenergic receptor. go-plus.json beta-1 adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031697 GO:0016079 biolink:BiologicalProcess synaptic vesicle exocytosis Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft. go-plus.json http://purl.obolibrary.org/obo/GO_0016079 goslim_synapse GO:0031694 biolink:MolecularActivity alpha-2A adrenergic receptor binding Binding to an alpha-2A adrenergic receptor. go-plus.json alpha-2A adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031694 GO:0031695 biolink:MolecularActivity alpha-2B adrenergic receptor binding Binding to an alpha-2B adrenergic receptor. go-plus.json alpha-2B adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031695 GO:0031692 biolink:MolecularActivity alpha-1B adrenergic receptor binding Binding to an alpha-1B adrenergic receptor. go-plus.json alpha-1B adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031692 GO:0016073 biolink:BiologicalProcess snRNA metabolic process The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein. go-plus.json snRNA metabolism http://purl.obolibrary.org/obo/GO_0016073 goslim_drosophila|goslim_pombe GO:0016074 biolink:BiologicalProcess sno(s)RNA metabolic process The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. go-plus.json snoRNA metabolism|box C/D sRNA metabolic process http://purl.obolibrary.org/obo/GO_0016074 goslim_drosophila|goslim_pombe GO:0031693 biolink:MolecularActivity alpha-1D adrenergic receptor binding Binding to an alpha-1D adrenergic receptor. go-plus.json alpha-1D adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031693 GO:0016075 biolink:BiologicalProcess rRNA catabolic process The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes. go-plus.json rRNA catabolism|rRNA degradation|rRNA breakdown http://purl.obolibrary.org/obo/GO_0016075 GO:0031690 biolink:MolecularActivity adrenergic receptor binding Binding to an adrenergic receptor. go-plus.json adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031690 CHEBI:91079 biolink:ChemicalSubstance purinergic receptor P2 antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_91079 GO:0016076 biolink:BiologicalProcess snRNA catabolic process The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein. go-plus.json snRNA degradation|snRNA breakdown|snRNA catabolism http://purl.obolibrary.org/obo/GO_0016076 GO:0031691 biolink:MolecularActivity alpha-1A adrenergic receptor binding Binding to an alpha-1A adrenergic receptor. go-plus.json alpha-1A adrenergic receptor ligand http://purl.obolibrary.org/obo/GO_0031691 GO:0016050 biolink:BiologicalProcess vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. go-plus.json vesicle organization and biogenesis|vesicle organisation http://purl.obolibrary.org/obo/GO_0016050 goslim_yeast|goslim_pir GO:0031689 biolink:MolecularActivity A3 adenosine receptor binding Binding to an A3 adenosine receptor. go-plus.json A3 adenosine receptor ligand http://purl.obolibrary.org/obo/GO_0031689 GO:0031687 biolink:MolecularActivity A2A adenosine receptor binding Binding to an A2A adenosine receptor. go-plus.json A2A adenosine receptor ligand http://purl.obolibrary.org/obo/GO_0031687 GO:0031688 biolink:MolecularActivity A2B adenosine receptor binding Binding to an A2B adenosine receptor. go-plus.json A2B adenosine receptor ligand http://purl.obolibrary.org/obo/GO_0031688 PATO:0001236 biolink:OntologyClass process quality A quality which inheres in an process. go-plus.json quality of a process|quality of process|quality of occurrent|relational quality of occurrent http://purl.obolibrary.org/obo/PATO_0001236 CHEBI:136389 biolink:ChemicalSubstance 5-[(9Z)-octadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136389 chebi_ph7_3 GO:0016048 biolink:BiologicalProcess detection of temperature stimulus The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. go-plus.json detection of temperature|perception of temperature|detection of thermal stimulus http://purl.obolibrary.org/obo/GO_0016048 GO:0016049 biolink:BiologicalProcess cell growth The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. go-plus.json non-developmental cell growth|metabolic process resulting in cell growth|cellular growth|cell expansion|non-developmental growth of a unicellular organism|metabolism resulting in cell growth|growth of cell http://purl.obolibrary.org/obo/GO_0016049 gocheck_do_not_annotate|goslim_pir|goslim_plant|goslim_drosophila GO:0031685 biolink:MolecularActivity adenosine receptor binding Binding to an adenosine receptor. go-plus.json adenosine receptor ligand http://purl.obolibrary.org/obo/GO_0031685 GO:0016044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016044 GO:0031686 biolink:MolecularActivity A1 adenosine receptor binding Binding to an A1 adenosine receptor. go-plus.json A1 adenosine receptor ligand http://purl.obolibrary.org/obo/GO_0031686 GO:0016045 biolink:BiologicalProcess detection of bacterium The series of events in which a stimulus from a bacterium is received and converted into a molecular signal. go-plus.json detection of bacteria|perception of bacteria|perception of bacterium http://purl.obolibrary.org/obo/GO_0016045 GO:0016046 biolink:BiologicalProcess detection of fungus The series of events in which a stimulus from a fungus is received and converted into a molecular signal. go-plus.json detection of parasitic fungus|perception of parasitic fungus|detection of fungi|perception of parasitic fungi|detection of parasitic fungi|perception of fungus|perception of fungi http://purl.obolibrary.org/obo/GO_0016046 GO:0031683 biolink:MolecularActivity G-protein beta/gamma-subunit complex binding Binding to a complex of G-protein beta/gamma subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0031683 GO:0016047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016047 GO:0031684 biolink:BiologicalProcess obsolete heterotrimeric G-protein complex cycle OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0031684 GO:0016040 biolink:MolecularActivity glutamate synthase (NADH) activity Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH. EC:1.4.1.14|MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN|RHEA:13753|KEGG_REACTION:R00093 go-plus.json L-glutamate:NAD+ oxidoreductase (transaminating)|NADH-glutamate synthase activity|NADH-dependent glutamate synthase activity|L-glutamate synthetase activity|GOGAT activity|glutamate (reduced nicotinamide adenine dinucleotide) synthase|NADH: GOGAT|L-glutamate synthase (NADH)|L-glutamate synthase activity http://purl.obolibrary.org/obo/GO_0016040 GO:0031681 biolink:MolecularActivity G-protein beta-subunit binding Binding to a G-protein beta subunit. go-plus.json G-beta protein subunit binding http://purl.obolibrary.org/obo/GO_0031681 GO:0031682 biolink:MolecularActivity G-protein gamma-subunit binding Binding to a G-protein gamma subunit. go-plus.json G-gamma protein subunit binding http://purl.obolibrary.org/obo/GO_0031682 GO:0016041 biolink:MolecularActivity glutamate synthase (ferredoxin) activity Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN|RHEA:12128|MetaCyc:PWY-4341|EC:1.4.7.1 go-plus.json L-glutamate:ferredoxin oxidoreductase (transaminating)|ferredoxin-glutamate synthase activity|ferredoxin-dependent glutamate synthase activity|glutamate synthase (ferredoxin-dependent) http://purl.obolibrary.org/obo/GO_0016041 GO:0016042 biolink:BiologicalProcess lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Wikipedia:Lipid_catabolism go-plus.json lipid catabolism|multicellular organism lipid catabolic process|lipolysis|lipid degradation|lipid breakdown|multicellular organismal lipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 GO:0031680 biolink:CellularComponent G-protein beta/gamma-subunit complex The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange. go-plus.json G-beta/G-gamma complex|heterotrimeric G-protein GTPase, beta-subunit http://purl.obolibrary.org/obo/GO_0031680 GO:0016043 biolink:BiologicalProcess cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. go-plus.json cell organisation|cell organization and biogenesis|cellular component organisation in other organism|cellular component organisation at cellular level|cellular component organization in other organism|cellular component organization at cellular level http://purl.obolibrary.org/obo/GO_0016043 goslim_mouse|goslim_agr|goslim_pir|goslim_plant GO:0016060 biolink:BiologicalProcess metarhodopsin inactivation The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it. go-plus.json http://purl.obolibrary.org/obo/GO_0016060 GO:0016061 biolink:BiologicalProcess regulation of light-activated channel activity Any process that modulates the frequency, rate or extent of light-activated channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_0016061 GO:0031678 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031678 GO:0031679 biolink:MolecularActivity NADH dehydrogenase (plastoquinone) activity Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol. go-plus.json NADH:plastoquinone reductase activity http://purl.obolibrary.org/obo/GO_0031679 GO:0031676 biolink:CellularComponent plasma membrane-derived thylakoid membrane The pigmented membrane of a plasma membrane-derived thylakoid. go-plus.json plasma membrane thylakoid membrane http://purl.obolibrary.org/obo/GO_0031676 GO:0031677 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031677 GO:0065010 biolink:CellularComponent extracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. go-plus.json extracellular membrane-enclosed organelle http://purl.obolibrary.org/obo/GO_0065010 PATO:0001241 biolink:OntologyClass physical object quality A quality which inheres in a continuant. go-plus.json multiply inhering quality of a physical entity|quality of continuant|quality of a continuant|quality of an object|monadic quality of an object|monadic quality of continuant|quality of a single physical entity|monadic quality of a continuant http://purl.obolibrary.org/obo/PATO_0001241 GO:0016059 biolink:BiologicalProcess deactivation of rhodopsin mediated signaling The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon). go-plus.json rod response recovery|deactivation of rhodopsin mediated signalling http://purl.obolibrary.org/obo/GO_0016059 GO:0016055 biolink:BiologicalProcess Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. go-plus.json Wg signaling pathway|frizzled signaling pathway|Wnt receptor signalling pathway|Wingless signaling pathway|Wingless signalling pathway|Wnt-activated signaling pathway|frizzled signalling pathway|Wnt receptor signaling pathway|Wg signalling pathway http://purl.obolibrary.org/obo/GO_0016055 GO:0031674 biolink:CellularComponent I band A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end. Wikipedia:Sarcomere#bands go-plus.json I disc|J disc|isotropic disc http://purl.obolibrary.org/obo/GO_0031674 GO:0016056 biolink:BiologicalProcess rhodopsin mediated signaling pathway The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response. go-plus.json rhodopsin signaling|rhodopsin mediated signalling pathway|rhodopsin mediated phototransduction http://purl.obolibrary.org/obo/GO_0016056 GO:0031675 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031675 GO:0016057 biolink:BiologicalProcess regulation of membrane potential in photoreceptor cell Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon. go-plus.json changes in polarization state of photoreceptor cell membrane http://purl.obolibrary.org/obo/GO_0016057 GO:0031672 biolink:CellularComponent A band The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line. Wikipedia:Sarcomere#bands go-plus.json transverse disc|Q disc|anisotropic disc|A disc http://purl.obolibrary.org/obo/GO_0031672 GO:0016058 biolink:BiologicalProcess maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon. go-plus.json maintenance of rhodopsin mediated signaling|maintenance of rhodopsin mediated signalling http://purl.obolibrary.org/obo/GO_0016058 GO:0031673 biolink:CellularComponent H zone A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments. Wikipedia:Sarcomere#bands go-plus.json H disc|H band http://purl.obolibrary.org/obo/GO_0031673 GO:0016051 biolink:BiologicalProcess carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. go-plus.json anabolic carbohydrate metabolic process|carbohydrate anabolism|carbohydrate synthesis|carbohydrate formation|anabolic carbohydrate metabolism|carbohydrate biosynthesis http://purl.obolibrary.org/obo/GO_0016051 GO:0031670 biolink:BiologicalProcess cellular response to nutrient Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0031670 CHEBI:136398 biolink:ChemicalSubstance N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136398 chebi_ph7_3 GO:0031671 biolink:BiologicalProcess primary cell septum biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division. go-plus.json http://purl.obolibrary.org/obo/GO_0031671 GO:0016052 biolink:BiologicalProcess carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. go-plus.json single-organism carbohydrate catabolic process|carbohydrate breakdown|catabolic carbohydrate metabolic process|catabolic carbohydrate metabolism|carbohydrate catabolism|multicellular organismal carbohydrate catabolic process|carbohydrate degradation http://purl.obolibrary.org/obo/GO_0016052 CHEBI:136396 biolink:ChemicalSubstance 4-O-[1-D-ribitylphosphono-(2R)-1-glycerylphosphono]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136396 GO:0016053 biolink:BiologicalProcess organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. go-plus.json organic acid anabolism|organic acid synthesis|organic acid formation|organic acid biosynthesis http://purl.obolibrary.org/obo/GO_0016053 GO:0016054 biolink:BiologicalProcess organic acid catabolic process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. go-plus.json organic acid breakdown|organic acid catabolism|organic acid degradation http://purl.obolibrary.org/obo/GO_0016054 CHEBI:136397 biolink:ChemicalSubstance (2xi)-3-deoxy-7-O-phosphonato-beta-D-threo-hept-6-ulopyranosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136397 chebi_ph7_3 GO:0031669 biolink:BiologicalProcess cellular response to nutrient levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. go-plus.json http://purl.obolibrary.org/obo/GO_0031669 GO:0031667 biolink:BiologicalProcess response to nutrient levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. go-plus.json http://purl.obolibrary.org/obo/GO_0031667 GO:0031668 biolink:BiologicalProcess cellular response to extracellular stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0031668 GO:0031665 biolink:BiologicalProcess negative regulation of lipopolysaccharide-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. go-plus.json down-regulation of lipopolysaccharide-mediated signaling pathway|inhibition of lipopolysaccharide-mediated signaling pathway|negative regulation of lipopolysaccharide-mediated signalling pathway|negative regulation of LPS-mediated signaling pathway|down regulation of lipopolysaccharide-mediated signaling pathway|downregulation of lipopolysaccharide-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0031665 GO:0031666 biolink:BiologicalProcess positive regulation of lipopolysaccharide-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. go-plus.json up regulation of lipopolysaccharide-mediated signaling pathway|activation of lipopolysaccharide-mediated signaling pathway|stimulation of lipopolysaccharide-mediated signaling pathway|up-regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signalling pathway|positive regulation of LPS-mediated signaling pathway|upregulation of lipopolysaccharide-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0031666 GO:0090008 biolink:BiologicalProcess hypoblast development The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast. go-plus.json http://purl.obolibrary.org/obo/GO_0090008 CHEBI:136369 biolink:ChemicalSubstance 5-[(9Z)-hexadecenoyloxy]octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136369 chebi_ph7_3 GO:0090009 biolink:BiologicalProcess primitive streak formation The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0090009 GO:0090006 biolink:BiologicalProcess regulation of linear element assembly Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase. go-plus.json regulation of linear element assembly http://purl.obolibrary.org/obo/GO_0090006 GO:0090007 biolink:BiologicalProcess obsolete regulation of mitotic anaphase OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic anaphase, a cell cycle process comprising the steps by which a cell progresses through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other. go-plus.json regulation of mitotic anaphase http://purl.obolibrary.org/obo/GO_0090007 GO:0016026 biolink:MolecularActivity obsolete proteasome endopeptidase core OBSOLETE. (Was not defined before being made obsolete). go-plus.json proteasome endopeptidase core http://purl.obolibrary.org/obo/GO_0016026 GO:0016027 biolink:CellularComponent inaD signaling complex A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD. go-plus.json inaD signalling complex http://purl.obolibrary.org/obo/GO_0016027 GO:0016028 biolink:CellularComponent rhabdomere The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction. go-plus.json http://purl.obolibrary.org/obo/GO_0016028 goslim_pir GO:0016029 biolink:CellularComponent subrhabdomeral cisterna A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase. go-plus.json SMC|submicrovillar cisterna http://purl.obolibrary.org/obo/GO_0016029 GO:0016022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016022 GO:0031663 biolink:BiologicalProcess lipopolysaccharide-mediated signaling pathway A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. go-plus.json lipopolysaccharide-mediated signalling pathway|LPS-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0031663 GO:0031664 biolink:BiologicalProcess regulation of lipopolysaccharide-mediated signaling pathway Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. go-plus.json regulation of lipopolysaccharide-mediated signalling pathway|regulation of LPS-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0031664 GO:0090001 biolink:BiologicalProcess replication fork arrest at tRNA locus A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit. go-plus.json http://purl.obolibrary.org/obo/GO_0090001 GO:0016023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016023 GO:0016024 biolink:BiologicalProcess CDP-diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. go-plus.json CDP-diacylglycerol anabolism|CDP-diacylglycerol synthesis|CDP-diacylglycerol formation|CDP-diacylglycerol biosynthesis http://purl.obolibrary.org/obo/GO_0016024 GO:0031661 biolink:BiologicalProcess obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle. go-plus.json G2/M-specific inhibition of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G2/M|G2/M-specific down-regulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity during G2/M|G2/M-specific down regulation of cyclin-dependent protein kinase activity|G2/M-specific downregulation of cyclin-dependent protein kinase activity|G2/M-specific negative regulation of cyclin-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_0031661 GO:0016025 biolink:MolecularActivity obsolete proteasome endopeptidase regulator OBSOLETE. (Was not defined before being made obsolete). go-plus.json proteasome endopeptidase regulator http://purl.obolibrary.org/obo/GO_0016025 GO:0031662 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031662 GO:0090004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090004 GO:0090005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090005 GO:0031660 biolink:BiologicalProcess obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle. go-plus.json G2/M-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G2/M|regulation of cyclin-dependent protein kinase activity during G2/M http://purl.obolibrary.org/obo/GO_0031660 GO:0016020 biolink:CellularComponent membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. Wikipedia:Biological_membrane go-plus.json membrane region|whole membrane|region of membrane http://purl.obolibrary.org/obo/GO_0016020 goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_flybase_ribbon|goslim_chembl|goslim_yeast|goslim_candida GO:0090002 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090002 GO:0016021 biolink:CellularComponent integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. Wikipedia:Transmembrane_protein go-plus.json integral to membrane|transmembrane http://purl.obolibrary.org/obo/GO_0016021 goslim_chembl GO:0090003 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090003 GO:0031658 biolink:BiologicalProcess obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle. go-plus.json negative regulation of cyclin-dependent protein kinase activity during G1/S|G1/S-specific down-regulation of cyclin-dependent protein kinase activity|G1/S-specific downregulation of cyclin-dependent protein kinase activity|G1/S-specific down regulation of cyclin-dependent protein kinase activity|G1/S-specific inhibition of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|G1/S-specific negative regulation of cyclin-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_0031658 GO:0031659 biolink:BiologicalProcess obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle. go-plus.json positive regulation of cyclin-dependent protein kinase activity during G1/S|G1/S-specific up regulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|G1/S-specific upregulation of cyclin-dependent protein kinase activity|G1/S-specific stimulation of cyclin-dependent protein kinase activity|G1/S-specific positive regulation of cyclin-dependent protein kinase activity|G1/S-specific up-regulation of cyclin-dependent protein kinase activity|G1/S-specific activation of cyclin-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_0031659 GO:0031656 biolink:BiologicalProcess positive regulation of heat dissipation Any process that activates or increases the rate or extent of heat dissipation. go-plus.json up regulation of heat dissipation|upregulation of heat dissipation|stimulation of heat dissipation|activation of heat dissipation|up-regulation of heat dissipation http://purl.obolibrary.org/obo/GO_0031656 GO:0031657 biolink:BiologicalProcess obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle. go-plus.json G1/S-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G1/S|regulation of cyclin-dependent protein kinase activity during G1/S http://purl.obolibrary.org/obo/GO_0031657 GO:0031654 biolink:BiologicalProcess regulation of heat dissipation Any process that modulates the rate or extent of heat dissipation. go-plus.json http://purl.obolibrary.org/obo/GO_0031654 GO:0031655 biolink:BiologicalProcess negative regulation of heat dissipation Any process that stops, prevents, or reduces the rate or extent of heat dissipation. go-plus.json downregulation of heat dissipation|down regulation of heat dissipation|inhibition of heat dissipation|down-regulation of heat dissipation http://purl.obolibrary.org/obo/GO_0031655 GO:0090019 biolink:BiologicalProcess obsolete regulation of transcription involved in anterior neural plate formation OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the anterior neural plate. go-plus.json http://purl.obolibrary.org/obo/GO_0090019 GO:0090017 biolink:BiologicalProcess anterior neural plate formation The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate. go-plus.json http://purl.obolibrary.org/obo/GO_0090017 GO:0090018 biolink:BiologicalProcess posterior neural plate formation The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate. go-plus.json http://purl.obolibrary.org/obo/GO_0090018 GO:0016037 biolink:BiologicalProcess light absorption The reception of a photon by a cell. go-plus.json absorption of light http://purl.obolibrary.org/obo/GO_0016037 RO:0001025 biolink:OntologyClass located_in RO:0001025 go-plus.json http://purl.obolibrary.org/obo/RO_0001025 GO:0016038 biolink:BiologicalProcess absorption of visible light The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm. go-plus.json http://purl.obolibrary.org/obo/GO_0016038 GO:0016039 biolink:BiologicalProcess absorption of UV light The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm. go-plus.json http://purl.obolibrary.org/obo/GO_0016039 GO:0090011 biolink:BiologicalProcess Wnt signaling pathway involved in primitive streak formation The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak. go-plus.json Wnt receptor signalling pathway involved in primitive streak formation|Wnt-activated signaling pathway involved in primitive streak formation|Wnt receptor signaling pathway involved in primitive streak formation http://purl.obolibrary.org/obo/GO_0090011 GO:0031652 biolink:BiologicalProcess positive regulation of heat generation Any process that activates or increases the rate or extent of heat generation. go-plus.json up regulation of heat generation|activation of heat generation|stimulation of heat generation|up-regulation of heat generation|upregulation of heat generation http://purl.obolibrary.org/obo/GO_0031652 GO:0016033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016033 GO:0090012 biolink:BiologicalProcess negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak. go-plus.json negative regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation http://purl.obolibrary.org/obo/GO_0090012 GO:0016034 biolink:MolecularActivity maleylacetoacetate isomerase activity Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate. RHEA:14817|UM-BBD_reactionID:r0106|EC:5.2.1.2|MetaCyc:MALEYLACETOACETATE-ISOMERASE-RXN|Reactome:R-HSA-71173 go-plus.json maleylacetoacetic isomerase activity|maleylacetone cis-trans-isomerase activity|maleylacetone isomerase activity|4-maleylacetoacetate cis-trans-isomerase activity http://purl.obolibrary.org/obo/GO_0016034 GO:0031653 biolink:BiologicalProcess heat dissipation Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature. go-plus.json http://purl.obolibrary.org/obo/GO_0031653 CHEBI:136373 biolink:ChemicalSubstance 9-(octadecanoyloxy)octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136373 chebi_ph7_3 GO:0031650 biolink:BiologicalProcess regulation of heat generation Any process that modulates the rate or extent of heat generation. go-plus.json http://purl.obolibrary.org/obo/GO_0031650 GO:0016035 biolink:CellularComponent zeta DNA polymerase complex A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer. go-plus.json http://purl.obolibrary.org/obo/GO_0016035 CHEBI:136370 biolink:ChemicalSubstance 5-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136370 chebi_ph7_3 GO:0031651 biolink:BiologicalProcess negative regulation of heat generation Any process that stops, prevents, or reduces the rate or extent of heat generation. go-plus.json downregulation of heat generation|down-regulation of heat generation|inhibition of heat generation|down regulation of heat generation http://purl.obolibrary.org/obo/GO_0031651 GO:0090010 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in primitive streak formation A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the primitive streak. go-plus.json transforming growth factor beta receptor signalling pathway involved in primitive streak formation|TGFbeta signaling pathway involved in primitive streak formation http://purl.obolibrary.org/obo/GO_0090010 GO:0016036 biolink:BiologicalProcess cellular response to phosphate starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0016036 GO:0090015 biolink:BiologicalProcess positive regulation of leaflet formation by auxin mediated signaling pathway Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin. go-plus.json positive regulation of leaflet formation by auxin mediated signalling pathway http://purl.obolibrary.org/obo/GO_0090015 GO:0090016 biolink:BiologicalProcess regulation of leaflet formation Any process that modulates the frequency, rate or extent of leaflet formation. go-plus.json http://purl.obolibrary.org/obo/GO_0090016 GO:0016030 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016030 GO:0016031 biolink:BiologicalProcess tRNA import into mitochondrion The process in which a tRNA is transported from the cytosol into the mitochondrial matrix. go-plus.json cytoplasmic tRNA, mitochondrial import|cytoplasmic tRNA import into mitochondrion|mitochondrial import of cytoplasmic tRNA|cytoplasmic tRNA transport into mitochondrion|cytoplasmic tRNA import into mitochondria|nuclear-encoded tRNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0016031 GO:0090013 biolink:BiologicalProcess regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak. go-plus.json regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation http://purl.obolibrary.org/obo/GO_0090013 GO:0090014 biolink:BiologicalProcess leaflet formation The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf. go-plus.json http://purl.obolibrary.org/obo/GO_0090014 GO:0016032 biolink:BiologicalProcess viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. Wikipedia:Viral_life_cycle go-plus.json virus process|virulence|viral infection http://purl.obolibrary.org/obo/GO_0016032 goslim_pir|goslim_metagenomics GO:0031649 biolink:BiologicalProcess heat generation Any homeostatic process in which an organism produces heat, thereby raising its internal temperature. go-plus.json http://purl.obolibrary.org/obo/GO_0031649 GO:0031647 biolink:BiologicalProcess regulation of protein stability Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation. go-plus.json http://purl.obolibrary.org/obo/GO_0031647 goslim_pir GO:0031648 biolink:BiologicalProcess protein destabilization Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. go-plus.json protein destabilisation|negative regulation of protein stability http://purl.obolibrary.org/obo/GO_0031648 GO:0031645 biolink:BiologicalProcess negative regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. go-plus.json negative regulation of neurological process|negative regulation of neurophysiological process|down-regulation of neurological process|negative regulation of neurological system process|downregulation of neurological process|down regulation of neurological process|inhibition of neurological process http://purl.obolibrary.org/obo/GO_0031645 GO:0006689 biolink:BiologicalProcess ganglioside catabolic process The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues. go-plus.json ganglioside degradation|ganglioside catabolism|ganglioside breakdown http://purl.obolibrary.org/obo/GO_0006689 GO:0031646 biolink:BiologicalProcess positive regulation of nervous system process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. go-plus.json stimulation of neurological process|up-regulation of neurological process|activation of neurological process|positive regulation of neurological process|positive regulation of neurophysiological process|positive regulation of neurological system process|up regulation of neurological process|upregulation of neurological process http://purl.obolibrary.org/obo/GO_0031646 GO:0031643 biolink:BiologicalProcess positive regulation of myelination Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. go-plus.json up regulation of myelination|activation of myelination|stimulation of myelination|up-regulation of myelination|upregulation of myelination http://purl.obolibrary.org/obo/GO_0031643 GO:0006687 biolink:BiologicalProcess glycosphingolipid metabolic process The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. go-plus.json glycosphingolipid metabolism http://purl.obolibrary.org/obo/GO_0006687 GO:0006688 biolink:BiologicalProcess glycosphingolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. go-plus.json glycosphingolipid biosynthesis|glycosphingolipid anabolism|glycosphingolipid synthesis|glycosphingolipid formation http://purl.obolibrary.org/obo/GO_0006688 GO:0031644 biolink:BiologicalProcess regulation of nervous system process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. go-plus.json regulation of neurological system process|regulation of neurological process|regulation of neurophysiological process http://purl.obolibrary.org/obo/GO_0031644 CHEBI:42090 biolink:ChemicalSubstance L-threitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42090 chebi_ph7_3 GO:0006685 biolink:BiologicalProcess sphingomyelin catabolic process The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. go-plus.json sphingomyelin degradation|sphingomyelin breakdown|sphingomyelin catabolism http://purl.obolibrary.org/obo/GO_0006685 GO:0006686 biolink:BiologicalProcess sphingomyelin biosynthetic process The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. go-plus.json sphingomyelin biosynthesis|sphingomyelin anabolism|sphingomyelin synthesis|sphingomyelin formation http://purl.obolibrary.org/obo/GO_0006686 GO:0006683 biolink:BiologicalProcess galactosylceramide catabolic process The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. go-plus.json galactosylceramide degradation|galactosylceramide catabolism|galactosylceramide breakdown http://purl.obolibrary.org/obo/GO_0006683 GO:0006684 biolink:BiologicalProcess sphingomyelin metabolic process The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine. go-plus.json sphingomyelin metabolism http://purl.obolibrary.org/obo/GO_0006684 GO:0006681 biolink:BiologicalProcess galactosylceramide metabolic process The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. go-plus.json galactosylceramide metabolism http://purl.obolibrary.org/obo/GO_0006681 GO:0006682 biolink:BiologicalProcess galactosylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. go-plus.json galactosylceramide synthesis|galactosylceramide formation|galactosylceramide biosynthesis|galactosylceramide anabolism http://purl.obolibrary.org/obo/GO_0006682 GO:0006680 biolink:BiologicalProcess glucosylceramide catabolic process The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. go-plus.json glucosylceramide breakdown|glucosylceramide catabolism|glucosylceramide degradation http://purl.obolibrary.org/obo/GO_0006680 GO:0016008 biolink:CellularComponent major mitochondrial derivative The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0016008 GO:0016009 biolink:CellularComponent minor mitochondrial derivative The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0016009 RO:0001019 biolink:OntologyClass RO:0001019 go-plus.json http://purl.obolibrary.org/obo/RO_0001019 GO:0016004 biolink:MolecularActivity phospholipase activator activity Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0016004 RO:0001015 biolink:OntologyClass RO:0001015 go-plus.json http://purl.obolibrary.org/obo/RO_0001015 GO:0016005 biolink:MolecularActivity phospholipase A2 activator activity Increases the activity of the enzyme phospholipase A2. go-plus.json http://purl.obolibrary.org/obo/GO_0016005 GO:0016006 biolink:CellularComponent Nebenkern A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme. go-plus.json http://purl.obolibrary.org/obo/GO_0016006 GO:0016007 biolink:CellularComponent mitochondrial derivative The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0016007 GO:0016000 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016000 GO:0031641 biolink:BiologicalProcess regulation of myelination Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. go-plus.json http://purl.obolibrary.org/obo/GO_0031641 CHEBI:4372 biolink:ChemicalSubstance (6S)-dehydrovomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_4372 chebi_ph7_3 GO:0031642 biolink:BiologicalProcess negative regulation of myelination Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. go-plus.json down-regulation of myelination|inhibition of myelination|down regulation of myelination|downregulation of myelination http://purl.obolibrary.org/obo/GO_0031642 GO:0016001 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016001 GO:0016002 biolink:MolecularActivity sulfite reductase activity Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor. MetaCyc:SULFITE-REDUCTASE-RXN go-plus.json hydrogen-sulfide:(acceptor) oxidoreductase activity|siroheme sulfite reductase activity|assimilatory-type sulfite reductase activity|hydrogen-sulfide:acceptor oxidoreductase activity|sulphite reductase activity|assimilatory sulfite reductase activity http://purl.obolibrary.org/obo/GO_0016002 GO:0031640 biolink:BiologicalProcess killing of cells of other organism Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. go-plus.json killing of cells of another, non-host, organism|killing of cells of another organism http://purl.obolibrary.org/obo/GO_0031640 goslim_pir GO:0016003 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016003 GO:0031638 biolink:BiologicalProcess zymogen activation The proteolytic processing of an inactive enzyme to an active form. go-plus.json zymogen activation by proteolytic cleavage http://purl.obolibrary.org/obo/GO_0031638 goslim_chembl GO:0031639 biolink:BiologicalProcess plasminogen activation The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. go-plus.json cleavage of plasminogen to plasmin http://purl.obolibrary.org/obo/GO_0031639 goslim_chembl GO:0031636 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031636 GO:0031637 biolink:BiologicalProcess regulation of neuronal synaptic plasticity in response to neurotrophin The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. go-plus.json neurotrophin-induced neuronal synaptic plasticity http://purl.obolibrary.org/obo/GO_0031637 GO:0031634 biolink:MolecularActivity replication fork barrier binding Binding to replication fork barriers, sites that inhibit the progress of replication forks. go-plus.json http://purl.obolibrary.org/obo/GO_0031634 GO:0031635 biolink:BiologicalProcess adenylate cyclase-inhibiting opioid receptor signaling pathway The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json opioid receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by opioid receptor signaling pathway|inhibition of adenylate cyclase activity by opioid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0031635 GO:0031632 biolink:BiologicalProcess positive regulation of synaptic vesicle fusion to presynaptic active zone membrane Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. go-plus.json stimulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic active zone membrane|positive regulation of synaptic vesicle fusion to pre-synaptic membrane|up-regulation of synaptic vesicle fusion to presynaptic membrane|up-regulation of synaptic vesicle fusion to presynaptic active zone membrane|upregulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic membrane|activation of synaptic vesicle fusion to presynaptic membrane http://purl.obolibrary.org/obo/GO_0031632 GO:0006698 biolink:BiologicalProcess obsolete ecdysone modification OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties. go-plus.json ecdysone modification http://purl.obolibrary.org/obo/GO_0006698 GO:0031633 biolink:CellularComponent xanthophore A chromatophore containing yellow pigment. go-plus.json http://purl.obolibrary.org/obo/GO_0031633 GO:0006699 biolink:BiologicalProcess bile acid biosynthetic process The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. go-plus.json bile acid anabolism|bile acid synthesis|bile acid biosynthesis|bile acid formation http://purl.obolibrary.org/obo/GO_0006699 GO:0006696 biolink:BiologicalProcess ergosterol biosynthetic process The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. go-plus.json ergosterol anabolism|ergosterol synthesis|ergosterol formation|ergosterol biosynthesis http://purl.obolibrary.org/obo/GO_0006696 GO:0006697 biolink:BiologicalProcess ecdysone biosynthetic process The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. go-plus.json ecdysone biosynthesis|ecdysone anabolism|ecdysone synthesis|ecdysone formation http://purl.obolibrary.org/obo/GO_0006697 GO:0006694 biolink:BiologicalProcess steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. Wikipedia:Steroid_metabolisms#Steroid_biosynthesis go-plus.json steroidogenesis|steroid anabolism|steroid biosynthesis|steroid synthesis|steroid formation http://purl.obolibrary.org/obo/GO_0006694 GO:0006695 biolink:BiologicalProcess cholesterol biosynthetic process The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json cholesterol anabolism|cholesterol synthesis|cholesterol formation|cholesterol biosynthesis http://purl.obolibrary.org/obo/GO_0006695 CHEBI:42088 biolink:ChemicalSubstance alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_42088 chebi_ph7_3 GO:0006692 biolink:BiologicalProcess prostanoid metabolic process The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure. go-plus.json prostanoid metabolism http://purl.obolibrary.org/obo/GO_0006692 GO:0006693 biolink:BiologicalProcess prostaglandin metabolic process The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. go-plus.json prostaglandin metabolism http://purl.obolibrary.org/obo/GO_0006693 GO:0006690 biolink:BiologicalProcess icosanoid metabolic process The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids. go-plus.json eicosanoid metabolic process|eicosanoid metabolism|icosanoid metabolism http://purl.obolibrary.org/obo/GO_0006690 GO:0006691 biolink:BiologicalProcess leukotriene metabolic process The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. go-plus.json leukotriene metabolism http://purl.obolibrary.org/obo/GO_0006691 GO:0016019 biolink:MolecularActivity peptidoglycan immune receptor activity Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response. go-plus.json peptidoglycan receptor activity|peptidoglycan recognition activity http://purl.obolibrary.org/obo/GO_0016019 GO:0016015 biolink:MolecularActivity morphogen activity Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0016015 GO:0016016 biolink:MolecularActivity obsolete short-wave-sensitive opsin OBSOLETE. An opsin with maximal absorption between 400 and 500 nm. go-plus.json short-wave-sensitive opsin http://purl.obolibrary.org/obo/GO_0016016 GO:0016017 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016017 GO:0016018 biolink:MolecularActivity cyclosporin A binding Binding to cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids. go-plus.json cyclophilin http://purl.obolibrary.org/obo/GO_0016018 GO:0031630 biolink:BiologicalProcess regulation of synaptic vesicle fusion to presynaptic active zone membrane Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. go-plus.json regulation of synaptic vesicle fusion to pre-synaptic membrane|regulation of synaptic vesicle fusion to presynaptic membrane http://purl.obolibrary.org/obo/GO_0031630 goslim_synapse GO:0016011 biolink:CellularComponent dystroglycan complex A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin. go-plus.json http://purl.obolibrary.org/obo/GO_0016011 CHEBI:136351 biolink:ChemicalSubstance 5,6-epoxy-(8Z,11Z,14Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136351 chebi_ph7_3 GO:0016012 biolink:CellularComponent sarcoglycan complex A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex. go-plus.json sarcoglycan-sarcospan complex http://purl.obolibrary.org/obo/GO_0016012 GO:0031631 biolink:BiologicalProcess negative regulation of synaptic vesicle fusion to presynaptic active zone membrane Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. go-plus.json downregulation of synaptic vesicle fusion to presynaptic membrane|down-regulation of synaptic vesicle fusion to presynaptic active zone membrane|negative regulation of synaptic vesicle fusion to pre-synaptic active zone membrane|down-regulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to pre-synaptic membrane|inhibition of synaptic vesicle fusion to presynaptic membrane|down regulation of synaptic vesicle fusion to presynaptic active zone membrane|downregulation of synaptic vesicle fusion to presynaptic active zone membrane|down regulation of synaptic vesicle fusion to presynaptic membrane http://purl.obolibrary.org/obo/GO_0031631 GO:0016013 biolink:CellularComponent syntrophin complex A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase. go-plus.json nitric oxide synthase-dystrophin complex, skeletal muscle http://purl.obolibrary.org/obo/GO_0016013 GO:0016014 biolink:CellularComponent dystrobrevin complex A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0016014 CHEBI:136354 biolink:ChemicalSubstance (4Z,7Z,10Z,12E,16Z)-14-hydroperoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136354 CHEBI:136355 biolink:ChemicalSubstance 5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136355 CHEBI:136352 biolink:ChemicalSubstance (7Z,10Z,13Z,15E,19Z)-17-hydroperoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136352 GO:0016010 biolink:CellularComponent dystrophin-associated glycoprotein complex A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase. go-plus.json dystrophin glycoprotein complex|DGC http://purl.obolibrary.org/obo/GO_0016010 goslim_pir CHEBI:136353 biolink:ChemicalSubstance (7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136353 CHEBI:32700 biolink:ChemicalSubstance arginine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32700 RO:0001000 biolink:OntologyClass derives_from RO:0001000 go-plus.json http://purl.obolibrary.org/obo/RO_0001000 CHEBI:32702 biolink:ChemicalSubstance L-tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32702 CHEBI:32704 biolink:ChemicalSubstance L-tryptophanium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32704 CHEBI:81672 biolink:ChemicalSubstance (2S)-methylsuccinyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_81672 CHEBI:81671 biolink:ChemicalSubstance (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_81671 CHEBI:91004 biolink:ChemicalSubstance D-galactopyranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91004 chebi_ph7_3 CHEBI:91005 biolink:ChemicalSubstance 5-[(E)-caffeoyl]shikimate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91005 chebi_ph7_3 CHEBI:91007 biolink:ChemicalSubstance aromatic carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91007 chebi_ph7_3 CHEBI:91000 biolink:ChemicalSubstance resolvin E1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91000 chebi_ph7_3 CHEBI:91001 biolink:ChemicalSubstance 18-oxoresolvin E1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91001 chebi_ph7_3 OBO:GOCHE_23530 biolink:OntologyClass substance with cytokinin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_23530 3_STAR CHEBI:91002 biolink:ChemicalSubstance sucrose 6(G)-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91002 chebi_ph7_3 CHEBI:91003 biolink:ChemicalSubstance asperlicins go-plus.json http://purl.obolibrary.org/obo/CHEBI_91003 CHEBI:32716 biolink:ChemicalSubstance D-tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32716 CHEBI:32717 biolink:ChemicalSubstance D-tryptophanium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32717 NCBITaxon:222544 biolink:OrganismalEntity Sordariomycetidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_222544 CHEBI:91020 biolink:ChemicalSubstance actinorhodin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91020 chebi_ph7_3 PR:000007988 biolink:Protein gastric inhibitory polypeptide receptor A glucagon-like receptor that is a translation product of the human GIPR gene or a 1:1 ortholog thereof. go-plus.json GIPR|glucose-dependent insulinotropic polypeptide receptor|GIP-R http://purl.obolibrary.org/obo/PR_000007988 CL:0007010 biolink:Cell preosteoblast Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells. go-plus.json osteoprogenitor cell http://purl.obolibrary.org/obo/CL_0007010 CL:0007011 biolink:Cell enteric neuron Neuron that is part of the enteric nervous system. go-plus.json http://purl.obolibrary.org/obo/CL_0007011 CHEBI:91025 biolink:ChemicalSubstance erythropoietin inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_91025 CHEBI:91010 biolink:ChemicalSubstance (2Z,4Z)-2,3-dichloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_91010 CHEBI:91011 biolink:ChemicalSubstance (2Z,4Z)-2,3-dichloromuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91011 chebi_ph7_3 CHEBI:91013 biolink:ChemicalSubstance D-ribose 5-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91013 chebi_ph7_3 CL:0007009 biolink:Cell prechondroblast Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. go-plus.json http://purl.obolibrary.org/obo/CL_0007009 CL:0007005 biolink:Cell notochordal cell Cell that is part of the notochord. go-plus.json http://purl.obolibrary.org/obo/CL_0007005 CL:0007006 biolink:Cell chordamesodermal cell Mesodermal cell that is axially located and gives rise to the cells of the notochord. go-plus.json axial mesodermal cell http://purl.obolibrary.org/obo/CL_0007006 CL:0007003 biolink:Cell preodontoblast Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell. go-plus.json http://purl.obolibrary.org/obo/CL_0007003 CL:0007004 biolink:Cell premigratory neural crest cell Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. go-plus.json http://purl.obolibrary.org/obo/CL_0007004 CL:0007000 biolink:Cell preameloblast Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins. go-plus.json http://purl.obolibrary.org/obo/CL_0007000 CHEBI:91036 biolink:ChemicalSubstance phosphatidylinositol 36:3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91036 chebi_ph7_3 GO:0016091 biolink:BiologicalProcess prenol biosynthetic process The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail. go-plus.json prenol biosynthesis|prenol anabolism|prenol synthesis|prenol formation http://purl.obolibrary.org/obo/GO_0016091 GO:0016092 biolink:BiologicalProcess prenol catabolic process The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail. go-plus.json prenol breakdown|prenol catabolism|prenol degradation http://purl.obolibrary.org/obo/GO_0016092 GO:0016093 biolink:BiologicalProcess polyprenol metabolic process The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. go-plus.json polyprenol metabolism http://purl.obolibrary.org/obo/GO_0016093 GO:0016094 biolink:BiologicalProcess polyprenol biosynthetic process The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. go-plus.json polyprenol anabolism|polyprenol synthesis|polyprenol formation|polyprenol biosynthesis http://purl.obolibrary.org/obo/GO_0016094 GO:0016090 biolink:BiologicalProcess prenol metabolic process The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail. go-plus.json prenol metabolism http://purl.obolibrary.org/obo/GO_0016090 NCBITaxon:2692248 biolink:OrganismalEntity core chlorophytes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2692248 NCBITaxon:28009 biolink:OrganismalEntity Choanoflagellata go-plus.json Choanoflagellida|choanoflagellates|Choanozoa|Choanoflagellatea|Choanomonada http://purl.obolibrary.org/obo/NCBITaxon_28009 GO:0016088 biolink:MolecularActivity obsolete insulin OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids. go-plus.json insulin http://purl.obolibrary.org/obo/GO_0016088 NCBITaxon:163735 biolink:OrganismalEntity Phaseoleae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_163735 GO:0016089 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016089 GO:0016084 biolink:MolecularActivity myostimulatory hormone activity The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0016084 GO:0016085 biolink:MolecularActivity myoinhibitory hormone activity The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0016085 GO:0016086 biolink:MolecularActivity obsolete allatostatin OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone. go-plus.json allatostatin http://purl.obolibrary.org/obo/GO_0016086 GO:0016087 biolink:MolecularActivity ecdysiostatic hormone activity The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0016087 GO:0016099 biolink:BiologicalProcess monoterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton. MetaCyc:PWY-3041 go-plus.json monoterpenoid anabolism|monoterpenoid synthesis|monoterpenoid formation|monoterpenoid biosynthesis http://purl.obolibrary.org/obo/GO_0016099 GO:0016095 biolink:BiologicalProcess polyprenol catabolic process The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. go-plus.json polyprenol catabolism|polyprenol degradation|polyprenol breakdown http://purl.obolibrary.org/obo/GO_0016095 NCBITaxon:163742 biolink:OrganismalEntity Trifolieae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_163742 GO:0016096 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016096 GO:0016097 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016097 GO:0016098 biolink:BiologicalProcess monoterpenoid metabolic process The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton. go-plus.json monoterpenoid metabolism http://purl.obolibrary.org/obo/GO_0016098 CHEBI:17030 biolink:ChemicalSubstance cycloartenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17030 chebi_ph7_3 CHEBI:32667 biolink:ChemicalSubstance L-glutaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32667 CHEBI:32668 biolink:ChemicalSubstance N(2)-L-glutamino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32668 CHEBI:32660 biolink:ChemicalSubstance asparaginate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32660 CHEBI:32661 biolink:ChemicalSubstance asparaginium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32661 CHEBI:32664 biolink:ChemicalSubstance asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32664 chebi_ph7_3 CHEBI:32665 biolink:ChemicalSubstance L-glutaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32665 CHEBI:17028 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17028 CHEBI:17029 biolink:ChemicalSubstance chitin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17029 chebi_ph7_3 CHEBI:32666 biolink:ChemicalSubstance L-glutaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32666 CHEBI:17026 biolink:ChemicalSubstance progesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17026 chebi_ph7_3 CHEBI:17027 biolink:ChemicalSubstance allysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17027 CHEBI:17025 biolink:ChemicalSubstance (S)-dihydroorotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17025 CHEBI:17023 biolink:ChemicalSubstance 2-hydroxyadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17023 CHEBI:17020 biolink:ChemicalSubstance glucomannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_17020 PR:000007928 biolink:Protein glial cell line-derived neurotrophic factor A protein that is a translation product of the human GDNF gene or a 1:1 ortholog thereof. go-plus.json astrocyte-derived trophic factor|GDNF|ATF http://purl.obolibrary.org/obo/PR_000007928 CHEBI:17021 biolink:ChemicalSubstance S-substituted glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17021 CHEBI:32678 biolink:ChemicalSubstance glutaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32678 CHEBI:32679 biolink:ChemicalSubstance glutaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32679 CHEBI:32672 biolink:ChemicalSubstance D-glutaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32672 CHEBI:32673 biolink:ChemicalSubstance D-glutaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32673 CHEBI:17019 biolink:ChemicalSubstance (R)-amygdalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17019 chebi_ph7_3 CHEBI:32674 biolink:ChemicalSubstance D-glutaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32674 CHEBI:32675 biolink:ChemicalSubstance N(2)-D-glutamino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32675 CHEBI:32677 biolink:ChemicalSubstance glutamine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32677 CHEBI:17015 biolink:ChemicalSubstance riboflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17015 CHEBI:17016 biolink:ChemicalSubstance L-methionine S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17016 CHEBI:17013 biolink:ChemicalSubstance dTMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17013 CHEBI:17011 biolink:ChemicalSubstance 5-dehydro-D-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17011 chebi_ph7_3 CHEBI:17012 biolink:ChemicalSubstance N-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17012 CHEBI:17010 biolink:ChemicalSubstance S-inosyl-L-homocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17010 CHEBI:17051 biolink:ChemicalSubstance fluoride go-plus.json http://purl.obolibrary.org/obo/CHEBI_17051 chebi_ph7_3 CHEBI:17052 biolink:ChemicalSubstance 3-phosphoshikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17052 CHEBI:17050 biolink:ChemicalSubstance 3-phosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17050 CHEBI:32646 biolink:ChemicalSubstance methioninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32646 CHEBI:32648 biolink:ChemicalSubstance methionine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32648 CHEBI:32640 biolink:ChemicalSubstance D-methionyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32640 CHEBI:32644 biolink:ChemicalSubstance methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32644 CHEBI:17048 biolink:ChemicalSubstance nororientaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17048 CHEBI:17049 biolink:ChemicalSubstance 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17049 NCBITaxon:340080 biolink:OrganismalEntity Parameciidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_340080 CHEBI:17047 biolink:ChemicalSubstance all-trans-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17047 CHEBI:17044 biolink:ChemicalSubstance D-glucitol 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17044 CHEBI:17045 biolink:ChemicalSubstance dinitrogen oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17045 chebi_ph7_3 CHEBI:17042 biolink:ChemicalSubstance tetrachlorohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17042 CHEBI:17043 biolink:ChemicalSubstance biphenyl-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17043 chebi_ph7_3 CHEBI:17040 biolink:ChemicalSubstance (carboxymethoxy)succinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17040 CHEBI:17041 biolink:ChemicalSubstance (S)-N-methylcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17041 CHEBI:32656 biolink:ChemicalSubstance D-asparaginate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32656 CHEBI:32657 biolink:ChemicalSubstance D-asparaginium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32657 CHEBI:32650 biolink:ChemicalSubstance L-asparaginate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32650 CHEBI:32651 biolink:ChemicalSubstance L-asparaginium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32651 CHEBI:32653 biolink:ChemicalSubstance D-asparaginyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32653 chebi_ph7_3 CHEBI:17039 biolink:ChemicalSubstance D-glucurono-6,2-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17039 chebi_ph7_3 CHEBI:17037 biolink:ChemicalSubstance geissoschizine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17037 chebi_ph7_3 CHEBI:17038 biolink:ChemicalSubstance fecosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17038 chebi_ph7_3 CHEBI:17036 biolink:ChemicalSubstance dibenzo[1,4]dioxine-2,3-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17036 chebi_ph7_3 CHEBI:17033 biolink:ChemicalSubstance biliverdin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17033 CHEBI:17034 biolink:ChemicalSubstance octadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17034 chebi_ph7_3 CHEBI:17031 biolink:ChemicalSubstance chelirubine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17031 chebi_ph7_3 CHEBI:17032 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17032 CHEBI:32623 biolink:ChemicalSubstance D-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32623 CHEBI:32624 biolink:ChemicalSubstance D-leucinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32624 PR:000007970 biolink:Protein growth hormone receptor A protein that is a translation product of the human GHR gene or a 1:1 ortholog thereof. go-plus.json GHR|somatotropin receptor|GH receptor http://purl.obolibrary.org/obo/PR_000007970 PR:000007971 biolink:Protein somatoliberin A protein that is a translation product of the human GHRH gene or a 1:1 ortholog thereof. go-plus.json somatorelin|GHRF|growth hormone-releasing factor|growth hormone-releasing hormone|somatocrinin|sermorelin|GRF|GHRH http://purl.obolibrary.org/obo/PR_000007971 CHEBI:32626 biolink:ChemicalSubstance D-leucino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32626 CHEBI:32627 biolink:ChemicalSubstance leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32627 CHEBI:32628 biolink:ChemicalSubstance leucinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32628 CHEBI:32629 biolink:ChemicalSubstance leucino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32629 CHEBI:32620 biolink:ChemicalSubstance L-leucinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32620 CHEBI:32622 biolink:ChemicalSubstance L-leucino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32622 CHEBI:81646 biolink:ChemicalSubstance Pretetramid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81646 CHEBI:32637 biolink:ChemicalSubstance D-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32637 CHEBI:32638 biolink:ChemicalSubstance D-methioninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32638 PR:000007972 biolink:Protein growth hormone-releasing hormone receptor A glucagon-like receptor that is a translation product of the human GHRHR gene or a 1:1 ortholog thereof. go-plus.json growth hormone-releasing factor receptor|GHRH receptor|GRF receptor|GHRHR|GRFR http://purl.obolibrary.org/obo/PR_000007972 CHEBI:32631 biolink:ChemicalSubstance L-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32631 PR:000007973 biolink:Protein appetite-regulating hormone A protein that is a translation product of the human GHRL gene or a 1:1 ortholog thereof. go-plus.json growth hormone secretagogue|growth hormone-releasing peptide|protein M46|motilin-related peptide|MTLRP|GHRL http://purl.obolibrary.org/obo/PR_000007973 CHEBI:32632 biolink:ChemicalSubstance L-methioninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32632 CHEBI:32609 biolink:ChemicalSubstance D-isoleucinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32609 CHEBI:32604 biolink:ChemicalSubstance L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32604 CHEBI:32605 biolink:ChemicalSubstance L-isoleucinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32605 CHEBI:32608 biolink:ChemicalSubstance D-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32608 CHEBI:17008 biolink:ChemicalSubstance N(2)-acyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17008 CHEBI:17009 biolink:ChemicalSubstance GDP-L-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17009 CHEBI:17006 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17006 chebi_ph7_3 CHEBI:32600 biolink:ChemicalSubstance tetracene go-plus.json http://purl.obolibrary.org/obo/CHEBI_32600 chebi_ph7_3 CHEBI:17007 biolink:ChemicalSubstance 1-(3,4-dimethoxyphenyl)ethane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17007 chebi_ph7_3 CHEBI:17002 biolink:ChemicalSubstance cholesteryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_17002 chebi_ph7_3 CHEBI:17000 biolink:ChemicalSubstance tropate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17000 chebi_ph7_3 CHEBI:17001 biolink:ChemicalSubstance 7,8-dihydroneopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17001 chebi_ph7_3 CHEBI:81667 biolink:ChemicalSubstance 2-hydroxy-5-methylquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_81667 CHEBI:32612 biolink:ChemicalSubstance isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32612 CHEBI:32613 biolink:ChemicalSubstance isoleucinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32613 CHEBI:81666 biolink:ChemicalSubstance 4-methyl-5-nitrocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_81666 chebi_ph7_3 NCBITaxon:981071 biolink:OrganismalEntity Brassiceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_981071 CHEBI:32619 biolink:ChemicalSubstance L-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32619 GO:0031627 biolink:BiologicalProcess telomeric loop formation The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region. go-plus.json T loop formation|T loop biosynthesis|t-loop biosynthesis|t-loop formation http://purl.obolibrary.org/obo/GO_0031627 GO:0031628 biolink:MolecularActivity opioid receptor binding Binding to an opioid receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0031628 GO:0006669 biolink:BiologicalProcess sphinganine-1-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. go-plus.json dihydrosphingosine-1-phosphate biosynthetic process|dihydrosphingosine-1-phosphate biosynthesis|sphinganine-1-phosphate biosynthesis|sphinganine-1-phosphate anabolism|sphinganine-1-phosphate synthesis|sphinganine-1-phosphate formation http://purl.obolibrary.org/obo/GO_0006669 GO:0031625 biolink:MolecularActivity ubiquitin protein ligase binding Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. go-plus.json ubiquitin ligase binding http://purl.obolibrary.org/obo/GO_0031625 GO:0031626 biolink:MolecularActivity beta-endorphin binding Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin. go-plus.json http://purl.obolibrary.org/obo/GO_0031626 GO:0006667 biolink:BiologicalProcess sphinganine metabolic process The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol. go-plus.json dihydrosphingosine metabolic process|dihydrosphingosine metabolism|sphinganine metabolism http://purl.obolibrary.org/obo/GO_0006667 GO:0031623 biolink:BiologicalProcess receptor internalization A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0031623 GO:0031624 biolink:MolecularActivity ubiquitin conjugating enzyme binding Binding to a ubiquitin conjugating enzyme, any of the E2 proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0031624 GO:0006668 biolink:BiologicalProcess sphinganine-1-phosphate metabolic process The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. go-plus.json dihydrosphingosine-1-phosphate metabolism|sphinganine-1-phosphate metabolism|dihydrosphingosine-1-phosphate metabolic process http://purl.obolibrary.org/obo/GO_0006668 GO:0031621 biolink:BiologicalProcess negative regulation of fever generation Any process that stops, prevents, or reduces the rate or extent of fever generation. go-plus.json down-regulation of fever|inhibition of fever|negative regulation of pyrexia|down regulation of fever|downregulation of fever http://purl.obolibrary.org/obo/GO_0031621 GO:0006665 biolink:BiologicalProcess sphingolipid metabolic process The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). go-plus.json sphingolipid metabolism http://purl.obolibrary.org/obo/GO_0006665 GO:0006666 biolink:BiologicalProcess 3-keto-sphinganine metabolic process The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine. go-plus.json 3-keto-dihydrosphingosine metabolic process|3-keto-dihydrosphingosine metabolism|3-keto-sphinganine metabolism http://purl.obolibrary.org/obo/GO_0006666 GO:0031622 biolink:BiologicalProcess positive regulation of fever generation Any process that activates or increases the frequency, rate, or extent of fever generation. go-plus.json stimulation of fever|up-regulation of fever|positive regulation of pyrexia|upregulation of fever|up regulation of fever|activation of fever http://purl.obolibrary.org/obo/GO_0031622 GO:0006663 biolink:BiologicalProcess platelet activating factor biosynthetic process The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli. go-plus.json platelet activating factor anabolism|platelet activating factor synthesis|PAF biosynthesis|PAF biosynthetic process|platelet activating factor formation|platelet activating factor biosynthesis http://purl.obolibrary.org/obo/GO_0006663 GO:0006664 biolink:BiologicalProcess glycolipid metabolic process The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent. go-plus.json glycolipid metabolism http://purl.obolibrary.org/obo/GO_0006664 GO:0006661 biolink:BiologicalProcess phosphatidylinositol biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. go-plus.json phosphatidylinositol synthesis|phosphatidylinositol formation|phosphoinositide biosynthetic process|phosphoinositide biosynthesis|phosphatidylinositol biosynthesis|PtdIns biosynthetic process|phosphatidylinositol anabolism|PtdIns biosynthesis http://purl.obolibrary.org/obo/GO_0006661 GO:0006662 biolink:BiologicalProcess glycerol ether metabolic process The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. go-plus.json glycerol ether metabolism http://purl.obolibrary.org/obo/GO_0006662 goslim_pir GO:0006660 biolink:BiologicalProcess phosphatidylserine catabolic process The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. go-plus.json phosphatidylserine degradation|phosphatidylserine catabolism|phosphatidylserine breakdown http://purl.obolibrary.org/obo/GO_0006660 GO:0031629 biolink:BiologicalProcess synaptic vesicle fusion to presynaptic active zone membrane Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft. go-plus.json synaptic vesicle fusion|synaptic vesicle fusion to pre-synaptic membrane|synaptic vesicle fusion to presynaptic membrane http://purl.obolibrary.org/obo/GO_0031629 goslim_synapse CHEBI:136447 biolink:ChemicalSubstance (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136447 chebi_ph7_3 CHEBI:136444 biolink:ChemicalSubstance (E)-1-(glutathion-S-yl)-2-(indol-3-yl)acetohydroximate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136444 chebi_ph7_3 CHEBI:136445 biolink:ChemicalSubstance 1-aci-nitro-2-(1H-indol-3-yl)ethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_136445 chebi_ph7_3 CHEBI:136448 biolink:ChemicalSubstance Cer(d18:0/18:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136448 chebi_ph7_3 GO:0031620 biolink:BiologicalProcess regulation of fever generation Any process that modulates the rate or extent of fever generation. go-plus.json regulation of pyrexia http://purl.obolibrary.org/obo/GO_0031620 CHEBI:136442 biolink:ChemicalSubstance desulfoglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136442 chebi_ph7_3 CHEBI:136443 biolink:ChemicalSubstance (5Z,8Z,11Z,17Z)-14,15-epoxyicosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136443 chebi_ph7_3 CHEBI:136440 biolink:ChemicalSubstance beta-D-thioglucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_136440 chebi_ph7_3 CHEBI:136441 biolink:ChemicalSubstance (5Z,8Z,14Z,17Z)-11,12-epoxyicosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136441 chebi_ph7_3 GO:0031616 biolink:CellularComponent spindle pole centrosome A centrosome from which one pole of a mitotic or meiotic spindle is organized. go-plus.json http://purl.obolibrary.org/obo/GO_0031616 GO:0031617 biolink:CellularComponent NMS complex A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes. go-plus.json Ndc80-MIND-Spc7 complex|KNL-1-Mis12-Ndc80|KMN kinetochore network http://purl.obolibrary.org/obo/GO_0031617 GO:0031614 biolink:CellularComponent obsolete ER proteasome regulatory particle, lid subcomplex OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031614 GO:0031615 biolink:CellularComponent cytosolic proteasome regulatory particle, lid subcomplex The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex. go-plus.json http://purl.obolibrary.org/obo/GO_0031615 GO:0031612 biolink:CellularComponent cytosolic proteasome regulatory particle, base subcomplex The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031612 GO:0006678 biolink:BiologicalProcess glucosylceramide metabolic process The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative. go-plus.json glucosylceramide metabolism http://purl.obolibrary.org/obo/GO_0006678 GO:0031613 biolink:CellularComponent nuclear proteasome regulatory particle, lid subcomplex The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031613 GO:0006679 biolink:BiologicalProcess glucosylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. go-plus.json glucosylceramide synthesis|glucosylceramide formation|glucosylceramide biosynthesis|glucosylceramide anabolism http://purl.obolibrary.org/obo/GO_0006679 GO:0006676 biolink:BiologicalProcess mannosyl diphosphorylinositol ceramide metabolic process The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative. go-plus.json M(IP)2C metabolic process|M(IP)2C metabolism|mannosyl diphosphorylinositol ceramide metabolism http://purl.obolibrary.org/obo/GO_0006676 GO:0031610 biolink:CellularComponent nuclear proteasome regulatory particle, base subcomplex The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031610 GO:0031611 biolink:CellularComponent obsolete ER proteasome regulatory particle, base subcomplex OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031611 GO:0006677 biolink:BiologicalProcess glycosylceramide metabolic process The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. go-plus.json glycosylceramide metabolism http://purl.obolibrary.org/obo/GO_0006677 GO:0006674 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006674 GO:0006675 biolink:BiologicalProcess mannosyl-inositol phosphorylceramide metabolic process The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative. go-plus.json mannose-inositol-P-ceramide (MIPC) metabolism|mannose inositol phosphoceramide metabolism|MIPC metabolism|mannosyl-inositol-phosphorylceramide metabolism|MIPC metabolic process|mannose inositol phosphoceramide metabolic process|mannose-inositol-P-ceramide (MIPC) metabolic process http://purl.obolibrary.org/obo/GO_0006675 GO:0006672 biolink:BiologicalProcess ceramide metabolic process The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. go-plus.json ceramide metabolism http://purl.obolibrary.org/obo/GO_0006672 GO:0006673 biolink:BiologicalProcess inositol phosphoceramide metabolic process The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group. go-plus.json inositol phosphorylceramide metabolic process|inositol phosphorylceramide metabolism|inositolphosphoceramide metabolism http://purl.obolibrary.org/obo/GO_0006673 GO:0006670 biolink:BiologicalProcess sphingosine metabolic process The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. go-plus.json sphing-4-enine metabolic process|(4E)-sphing-4-enine metabolic process|sphingosine metabolism|(4E)-sphing-4-enine metabolism|sphing-4-enine metabolism http://purl.obolibrary.org/obo/GO_0006670 GO:0006671 biolink:BiologicalProcess phytosphingosine metabolic process The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids. go-plus.json phytosphingosine metabolism http://purl.obolibrary.org/obo/GO_0006671 GO:0031618 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031618 GO:0031619 biolink:BiologicalProcess homologous chromosome orientation involved in meiotic metaphase I plate congression The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I. go-plus.json homologous chromosome orientation during meiosis|homologous chromosome orientation during meiosis I http://purl.obolibrary.org/obo/GO_0031619 CHEBI:136456 biolink:ChemicalSubstance glycolaldehyde phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136456 CHEBI:17099 biolink:ChemicalSubstance aspulvinone H go-plus.json http://purl.obolibrary.org/obo/CHEBI_17099 CHEBI:17097 biolink:ChemicalSubstance biphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_17097 chebi_ph7_3 CHEBI:17098 biolink:ChemicalSubstance veratraldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17098 chebi_ph7_3 GO:0031605 biolink:CellularComponent obsolete ER proteasome core complex, alpha-subunit complex OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031605 GO:0006649 biolink:BiologicalProcess phospholipid transfer to membrane The transfer of a phospholipid from its site of synthesis to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0006649 GO:0031606 biolink:CellularComponent cytosolic proteasome core complex, alpha-subunit complex The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031606 GO:0006647 biolink:BiologicalProcess phosphatidyl-N-monomethylethanolamine biosynthetic process The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. go-plus.json phosphatidyl-N-monomethylethanolamine anabolism|phosphatidyl-N-monomethylethanolamine biosynthesis|phosphatidyl-N-monomethylethanolamine synthesis|phosphatidyl-N-monomethylethanolamine formation|PMME biosynthetic process|PMME biosynthesis http://purl.obolibrary.org/obo/GO_0006647 GO:0031603 biolink:CellularComponent cytosolic proteasome core complex The core complex of a proteasome located in the cytosol of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031603 GO:0006648 biolink:BiologicalProcess dihydrosphingosine-1-P pathway A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase. go-plus.json http://purl.obolibrary.org/obo/GO_0006648 GO:0031604 biolink:CellularComponent nuclear proteasome core complex, alpha-subunit complex The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031604 GO:0031601 biolink:CellularComponent nuclear proteasome core complex The core complex of a proteasome located in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031601 GO:0006645 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006645 GO:0006646 biolink:BiologicalProcess phosphatidylethanolamine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. go-plus.json phosphatidylethanolamine anabolism|phosphatidylethanolamine synthesis|phosphatidylethanolamine formation|phosphatidylethanolamine biosynthesis http://purl.obolibrary.org/obo/GO_0006646 GO:0031602 biolink:CellularComponent obsolete ER proteasome core complex OBSOLETE. The core complex of a proteasome located in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031602 GO:0006643 biolink:BiologicalProcess membrane lipid metabolic process The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane. go-plus.json membrane lipid metabolism http://purl.obolibrary.org/obo/GO_0006643 GO:0006644 biolink:BiologicalProcess phospholipid metabolic process The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. go-plus.json phospholipid metabolism http://purl.obolibrary.org/obo/GO_0006644 GO:0031600 biolink:CellularComponent cytosolic proteasome regulatory particle A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031600 GO:0006641 biolink:BiologicalProcess triglyceride metabolic process The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins. go-plus.json triacylglycerol metabolic process|triacylglycerol metabolism|triglyceride metabolism http://purl.obolibrary.org/obo/GO_0006641 GO:0006642 biolink:BiologicalProcess triglyceride mobilization The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism. go-plus.json triacylglycerol mobilization http://purl.obolibrary.org/obo/GO_0006642 GO:0006640 biolink:BiologicalProcess monoacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. go-plus.json monoglyceride biosynthesis|monoglyceride biosynthetic process|monoacylglycerol biosynthesis|monoacylglycerol anabolism|monoacylglycerol synthesis|monoacylglycerol formation http://purl.obolibrary.org/obo/GO_0006640 GO:0031609 biolink:CellularComponent cytosolic proteasome core complex, beta-subunit complex The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031609 GO:0031607 biolink:CellularComponent nuclear proteasome core complex, beta-subunit complex The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031607 GO:0031608 biolink:CellularComponent obsolete ER proteasome core complex, beta-subunit complex OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0031608 CHEBI:136424 biolink:ChemicalSubstance (E)-omega-[(methylsulfanyl)alkyl]thiohydroximate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136424 chebi_ph7_3 CHEBI:136425 biolink:ChemicalSubstance omega-(methylsulfanyl)alkyl desulfoglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136425 chebi_ph7_3 CHEBI:136422 biolink:ChemicalSubstance (Z)-desulfoglucotropeolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_136422 chebi_ph7_3 CHEBI:136428 biolink:ChemicalSubstance N-hydroxyimidothioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136428 chebi_ph7_3 PATO:0001199 biolink:OntologyClass linear go-plus.json http://purl.obolibrary.org/obo/PATO_0001199 CHEBI:136420 biolink:ChemicalSubstance 3'-end 5'-phosphate-ribonucleotide(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136420 chebi_ph7_3 GO:0006658 biolink:BiologicalProcess phosphatidylserine metabolic process The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes. go-plus.json phosphatidylserine metabolism http://purl.obolibrary.org/obo/GO_0006658 GO:0006659 biolink:BiologicalProcess phosphatidylserine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. go-plus.json phosphatidylserine anabolism|phosphatidylserine synthesis|phosphatidylserine formation|phosphatidylserine biosynthesis http://purl.obolibrary.org/obo/GO_0006659 GO:0006656 biolink:BiologicalProcess phosphatidylcholine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. go-plus.json phosphatidylcholine biosynthesis|phosphatidylcholine anabolism|phosphatidylcholine synthesis|phosphatidylcholine formation http://purl.obolibrary.org/obo/GO_0006656 GO:0006657 biolink:BiologicalProcess CDP-choline pathway The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine. MetaCyc:PWY3O-450 go-plus.json Kennedy pathway|phosphatidylcholine biosynthesis from choline http://purl.obolibrary.org/obo/GO_0006657 GO:0006654 biolink:BiologicalProcess phosphatidic acid biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. go-plus.json phosphatidic acid biosynthesis|phosphatidic acid anabolism|phosphatidic acid synthesis|phosphatidic acid formation http://purl.obolibrary.org/obo/GO_0006654 GO:0006655 biolink:BiologicalProcess phosphatidylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. go-plus.json phosphatidylglycerol anabolism|phosphatidylglycerol synthesis|phosphatidylglycerol formation|phosphatidylglycerol biosynthesis http://purl.obolibrary.org/obo/GO_0006655 GO:0006652 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006652 GO:0006653 biolink:BiologicalProcess 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin. go-plus.json lecithin metabolic process|1,2-diacyl-sn-glycero-3-phosphocholine metabolism http://purl.obolibrary.org/obo/GO_0006653 GO:0006650 biolink:BiologicalProcess glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. go-plus.json glycerophospholipid metabolism|alpha-glycerophosphate pathway|phosphoglyceride metabolic process|phosphoglyceride metabolism http://purl.obolibrary.org/obo/GO_0006650 GO:0006651 biolink:BiologicalProcess diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. go-plus.json diacylglycerol anabolism|diacylglycerol synthesis|diacylglycerol formation|diglyceride biosynthesis|diacylglycerol biosynthesis http://purl.obolibrary.org/obo/GO_0006651 CHEBI:136435 biolink:ChemicalSubstance omega-[(methylsulfinyl)alkyl]glucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136435 chebi_ph7_3 CHEBI:136436 biolink:ChemicalSubstance 2-hydroxy-(indol-3-yl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136436 chebi_ph7_3 CHEBI:136433 biolink:ChemicalSubstance 2,5-diimino-3,4-bis(indol-3-yl)hexanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136433 CHEBI:136434 biolink:ChemicalSubstance omega-[(methylsulfanyl)alkyl]glucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136434 chebi_ph7_3 CHEBI:136439 biolink:ChemicalSubstance (5Z,11Z,14Z,17Z)-8,9-epoxyicosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136439 chebi_ph7_3 CHEBI:136437 biolink:ChemicalSubstance 3,4-bis(7-chloroindol-3-yl)-2,5-diiminohexanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136437 CHEBI:136438 biolink:ChemicalSubstance D-thioglucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_136438 chebi_ph7_3 CHEBI:136432 biolink:ChemicalSubstance (E)-2-(indol-3-yl)-1-thioacetohydroximate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136432 chebi_ph7_3 GO:0006627 biolink:BiologicalProcess protein processing involved in protein targeting to mitochondrion The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments. go-plus.json mitochondrial processing|mitochondrial protein processing during import http://purl.obolibrary.org/obo/GO_0006627 CHEBI:17073 biolink:ChemicalSubstance Cypridina luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17073 GO:0006628 biolink:BiologicalProcess obsolete mitochondrial translocation OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery. go-plus.json mitochondrial translocation http://purl.obolibrary.org/obo/GO_0006628 CHEBI:17074 biolink:ChemicalSubstance cycasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17074 chebi_ph7_3 CHEBI:17071 biolink:ChemicalSubstance glycolaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17071 chebi_ph7_3 GO:0006625 biolink:BiologicalProcess protein targeting to peroxisome The process of directing proteins towards the peroxisome, usually using signals contained within the protein. go-plus.json protein-peroxisome targeting http://purl.obolibrary.org/obo/GO_0006625 GO:0006626 biolink:BiologicalProcess protein targeting to mitochondrion The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein. go-plus.json mitochondrial translocation|protein import into mitochondrion|protein targeting to mitochondria|mitochondrial protein import|protein-mitochondrial targeting http://purl.obolibrary.org/obo/GO_0006626 CHEBI:17072 biolink:ChemicalSubstance N-amidino-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17072 GO:0006623 biolink:BiologicalProcess protein targeting to vacuole The process of directing proteins towards the vacuole, usually using signals contained within the protein. go-plus.json protein-vacuolar targeting|vacuolar protein sorting|protein vacuolar targeting|protein-vacuole targeting http://purl.obolibrary.org/obo/GO_0006623 GO:0006624 biolink:BiologicalProcess vacuolar protein processing Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes. go-plus.json vacuolar protein maturation|vacuolar proteolysis http://purl.obolibrary.org/obo/GO_0006624 GO:0006621 biolink:BiologicalProcess protein retention in ER lumen The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER. go-plus.json maintenance of protein location in ER lumen http://purl.obolibrary.org/obo/GO_0006621 GO:0006622 biolink:BiologicalProcess protein targeting to lysosome The process of directing proteins towards the lysosome using signals contained within the protein. go-plus.json protein-lysosome targeting http://purl.obolibrary.org/obo/GO_0006622 GO:0006620 biolink:BiologicalProcess posttranslational protein targeting to endoplasmic reticulum membrane The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane. go-plus.json posttranslational endoplasmic reticulum protein-membrane targeting|SRP-independent endoplasmic reticulum protein-membrane targeting|posttranslational endoplasmic reticulum membrane targeting|posttranslational protein endoplasmic reticulum membrane targeting|posttranslational protein targeting to ER membrane http://purl.obolibrary.org/obo/GO_0006620 CHEBI:136408 biolink:ChemicalSubstance 12-hydroxy-(5Z,8Z,10E,14Z)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136408 chebi_ph7_3 CHEBI:136409 biolink:ChemicalSubstance 15-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136409 chebi_ph7_3 CHEBI:136400 biolink:ChemicalSubstance 8(S),15(S)-DiHPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_136400 CHEBI:136401 biolink:ChemicalSubstance 14(R),15(S)-DiHPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_136401 CHEBI:136406 biolink:ChemicalSubstance 13-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136406 CHEBI:4439 biolink:ChemicalSubstance dermatan go-plus.json http://purl.obolibrary.org/obo/CHEBI_4439 CHEBI:136407 biolink:ChemicalSubstance 5-hydroxy-(6E,8Z,11Z,14Z)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136407 chebi_ph7_3 CHEBI:17068 biolink:ChemicalSubstance 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_17068 CHEBI:17069 biolink:ChemicalSubstance 3-hydroxybenzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17069 chebi_ph7_3 CHEBI:4431 biolink:ChemicalSubstance deoxyribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_4431 CHEBI:17066 biolink:ChemicalSubstance (R)-3-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17066 GO:0006629 biolink:BiologicalProcess lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. Wikipedia:Lipid_metabolism go-plus.json lipid metabolism http://purl.obolibrary.org/obo/GO_0006629 goslim_plant|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr CHEBI:17064 biolink:ChemicalSubstance 4-nitroaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17064 chebi_ph7_3 CHEBI:17065 biolink:ChemicalSubstance 3',5'-cyclic CMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17065 GO:0006638 biolink:BiologicalProcess neutral lipid metabolic process The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity. go-plus.json neutral lipid metabolism http://purl.obolibrary.org/obo/GO_0006638 CHEBI:17062 biolink:ChemicalSubstance primary aliphatic amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17062 CHEBI:17063 biolink:ChemicalSubstance L-erythrulose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17063 GO:0006639 biolink:BiologicalProcess acylglycerol metabolic process The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. go-plus.json glyceride metabolic process|glyceride metabolism|acylglycerol metabolism http://purl.obolibrary.org/obo/GO_0006639 GO:0006636 biolink:BiologicalProcess unsaturated fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms. MetaCyc:PWY-762|MetaCyc:PWY-782 go-plus.json unsaturated fatty acid formation|fatty acid desaturation|unsaturated fatty acid biosynthesis|unsaturated fatty acid anabolism|unsaturated fatty acid synthesis|polyunsaturated fatty acid biosynthesis http://purl.obolibrary.org/obo/GO_0006636 GO:0006637 biolink:BiologicalProcess acyl-CoA metabolic process The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group. go-plus.json acyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0006637 CHEBI:17061 biolink:ChemicalSubstance D-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17061 GO:0006634 biolink:BiologicalProcess hexadecanal biosynthetic process The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde. go-plus.json palmitaldehyde biosynthesis|palmitaldehyde biosynthetic process|hexadecanal anabolism|hexadecanal synthesis|hexadecanal formation|hexadecanal biosynthesis http://purl.obolibrary.org/obo/GO_0006634 GO:0006635 biolink:BiologicalProcess fatty acid beta-oxidation A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). go-plus.json http://purl.obolibrary.org/obo/GO_0006635 GO:0006632 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006632 GO:0006633 biolink:BiologicalProcess fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. MetaCyc:PWY-5156|MetaCyc:PWY-4381|MetaCyc:FASYN-INITIAL-PWY|Wikipedia:Fatty_acid_synthesis go-plus.json fatty acid synthesis|fatty acid formation|fatty acid biosynthesis|fatty acid anabolism http://purl.obolibrary.org/obo/GO_0006633 GO:0006630 biolink:BiologicalProcess obsolete lipid binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json lipid binding http://purl.obolibrary.org/obo/GO_0006630 GO:0006631 biolink:BiologicalProcess fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. Wikipedia:Fatty_acid_metabolism go-plus.json fatty acid metabolism http://purl.obolibrary.org/obo/GO_0006631 CHEBI:42027 biolink:ChemicalSubstance 1,2-di-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_42027 chebi_ph7_3 CHEBI:136419 biolink:ChemicalSubstance 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136419 chebi_ph7_3 NCBITaxon:716546 biolink:OrganismalEntity leotiomyceta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_716546 CHEBI:136413 biolink:ChemicalSubstance adenosine-5'-diphospho-5'-(2'-deoxyribonucleotide) residue(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136413 chebi_ph7_3 CHEBI:136414 biolink:ChemicalSubstance adenosine-5'-diphospho-5'-ribonucleotide-2'-deoxyribonucleotide residue(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136414 chebi_ph7_3 CHEBI:136411 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19S,20R)-19,20-epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136411 chebi_ph7_3 CHEBI:136412 biolink:ChemicalSubstance 5'-end 2'-deoxyribonucleotide(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136412 chebi_ph7_3 CHEBI:136418 biolink:ChemicalSubstance guanosine-5'-diphospho-5'-(2'-deoxyribonucleotide)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136418 chebi_ph7_3 CHEBI:136415 biolink:ChemicalSubstance 5'-phosphate ribonucleotide-(2'-deoxyribonucleotide) residue(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136415 chebi_ph7_3 NCBITaxon:716545 biolink:OrganismalEntity saccharomyceta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_716545 CHEBI:136416 biolink:ChemicalSubstance 5'-end 2'-deoxyribonucleoside residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136416 chebi_ph7_3 CHEBI:17059 biolink:ChemicalSubstance 2-methylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17059 chebi_ph7_3 CHEBI:17057 biolink:ChemicalSubstance cellobiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17057 chebi_ph7_3 CHEBI:17058 biolink:ChemicalSubstance 3-dehydroecdysone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17058 chebi_ph7_3 CHEBI:136410 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19R,20S)-19,20-epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136410 chebi_ph7_3 CHEBI:17056 biolink:ChemicalSubstance 1-carboxyvinyl carboxyphosphonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17056 CHEBI:17053 biolink:ChemicalSubstance L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17053 GO:0006605 biolink:BiologicalProcess protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. Wikipedia:Protein_targeting go-plus.json nascent polypeptide association|protein sorting along secretory pathway http://purl.obolibrary.org/obo/GO_0006605 goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast CHEBI:17095 biolink:ChemicalSubstance cis-1,6-dihydroxy-4-methylcyclohexa-2,4-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17095 GO:0006606 biolink:BiologicalProcess protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus. go-plus.json protein transport from cytoplasm to nucleus|protein import into cell nucleus|establishment of protein localization to nucleus|protein nucleus import http://purl.obolibrary.org/obo/GO_0006606 CHEBI:17096 biolink:ChemicalSubstance strictosidine aglycone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17096 GO:0006603 biolink:BiologicalProcess phosphocreatine metabolic process The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle. go-plus.json phosphocreatine metabolism http://purl.obolibrary.org/obo/GO_0006603 GO:0006604 biolink:BiologicalProcess phosphoarginine metabolic process The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates. go-plus.json phosphoarginine metabolism http://purl.obolibrary.org/obo/GO_0006604 CHEBI:17094 biolink:ChemicalSubstance 2-dehydropantoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17094 GO:0006601 biolink:BiologicalProcess creatine biosynthetic process The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle. go-plus.json creatine formation|creatine biosynthesis|creatine anabolism|creatine synthesis http://purl.obolibrary.org/obo/GO_0006601 GO:0006602 biolink:BiologicalProcess creatinine catabolic process The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine. go-plus.json creatinine catabolism|creatinine degradation|creatinine breakdown http://purl.obolibrary.org/obo/GO_0006602 CHEBI:17092 biolink:ChemicalSubstance 3-chloro-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17092 GO:0006600 biolink:BiologicalProcess creatine metabolic process The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle. go-plus.json creatine metabolism http://purl.obolibrary.org/obo/GO_0006600 CHEBI:17090 biolink:ChemicalSubstance (1R,2R,3R)-prephytoene diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17090 CHEBI:32689 biolink:ChemicalSubstance D-argininium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32689 chebi_ph7_3 CHEBI:32681 biolink:ChemicalSubstance L-argininate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32681 CHEBI:32682 biolink:ChemicalSubstance L-argininium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32682 chebi_ph7_3 CHEBI:32683 biolink:ChemicalSubstance L-argininium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32683 CHEBI:32684 biolink:ChemicalSubstance L-arginyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32684 CHEBI:42017 biolink:ChemicalSubstance 2,4-dinitrophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42017 CHEBI:32688 biolink:ChemicalSubstance D-argininate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32688 CHEBI:17088 biolink:ChemicalSubstance monoacyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17088 GO:0006609 biolink:BiologicalProcess obsolete mRNA-binding (hnRNP) protein import into nucleus OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. go-plus.json mRNA-binding (hnRNP) protein-nucleus import|mRNA-binding (hnRNP) protein import into cell nucleus|mRNA-binding (hnRNP) protein transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0006609 CHEBI:17089 biolink:ChemicalSubstance glycoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_17089 GO:0006607 biolink:BiologicalProcess NLS-bearing protein import into nucleus The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope. go-plus.json NLS-bearing substrate-nucleus import|NLS-bearing substrate import into cell nucleus|NLS-bearing substrate import into nucleus|NLS-bearing substrate transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0006607 CHEBI:17087 biolink:ChemicalSubstance ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17087 chebi_ph7_3 GO:0006608 biolink:BiologicalProcess obsolete snRNP protein import into nucleus OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. go-plus.json snRNP protein-nucleus import|snRNP protein import into cell nucleus|snRNP protein transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0006608 GO:0006616 biolink:BiologicalProcess SRP-dependent cotranslational protein targeting to membrane, translocation The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. go-plus.json SRP-dependent cotranslational membrane targeting, translocation|SRP-dependent cotranslational protein-membrane targeting, translocation|translocation during SRP-dependent cotranslational protein targeting to membrane|ER translocation http://purl.obolibrary.org/obo/GO_0006616 CHEBI:17084 biolink:ChemicalSubstance 2-hydroxyglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17084 GO:0006617 biolink:BiologicalProcess SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting. go-plus.json signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, signal sequence recognition|SRP-dependent cotranslational protein-membrane targeting, signal sequence recognition http://purl.obolibrary.org/obo/GO_0006617 GO:0006614 biolink:BiologicalProcess SRP-dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. go-plus.json SRP-dependent cotranslational membrane targeting|ER translocation|SRP-dependent cotranslational protein-membrane targeting http://purl.obolibrary.org/obo/GO_0006614 CHEBI:17082 biolink:ChemicalSubstance L-2-aminoadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17082 GO:0006615 biolink:BiologicalProcess SRP-dependent cotranslational protein targeting to membrane, docking The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting. go-plus.json protein docking during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, docking|SRP-dependent cotranslational protein-membrane targeting, docking http://purl.obolibrary.org/obo/GO_0006615 CHEBI:17083 biolink:ChemicalSubstance 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17083 chebi_ph7_3 GO:0006612 biolink:BiologicalProcess protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the protein. go-plus.json protein-membrane targeting|protein membrane targeting http://purl.obolibrary.org/obo/GO_0006612 GO:0006613 biolink:BiologicalProcess cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria. go-plus.json cotranslational membrane targeting|cotranslational protein membrane targeting|cotranslational protein-membrane targeting http://purl.obolibrary.org/obo/GO_0006613 CHEBI:17081 biolink:ChemicalSubstance dimethylmaleate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17081 chebi_ph7_3 GO:0006610 biolink:BiologicalProcess ribosomal protein import into nucleus The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus. go-plus.json ribosomal protein-nucleus import|ribosomal protein import into cell nucleus|ribosomal protein transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0006610 GO:0006611 biolink:BiologicalProcess protein export from nucleus The directed movement of a protein from the nucleus into the cytoplasm. go-plus.json protein-nucleus export|protein export out of nucleus|copper-induced protein export from nucleus|protein export from cell nucleus|protein transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0006611 CHEBI:32695 biolink:ChemicalSubstance argininate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32695 CHEBI:32696 biolink:ChemicalSubstance argininium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32696 chebi_ph7_3 CHEBI:32697 biolink:ChemicalSubstance argininium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32697 CHEBI:4429 biolink:ChemicalSubstance deoxypodophyllotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_4429 chebi_ph7_3 CHEBI:32699 biolink:ChemicalSubstance argininium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32699 CHEBI:17079 biolink:ChemicalSubstance (S)-3'-hydroxy-N-methylcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17079 CHEBI:17077 biolink:ChemicalSubstance 2-carboxy-D-arabinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17077 CHEBI:17078 biolink:ChemicalSubstance L-gamma-glutamyl-L-cysteinyl-beta-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17078 GO:0006618 biolink:BiologicalProcess SRP-dependent cotranslational protein targeting to membrane, signal sequence processing The removal of the signal peptide from a nascent protein during cotranslational membrane targeting. go-plus.json SRP-dependent cotranslational protein-membrane targeting, signal sequence processing|signal sequence processing during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, signal sequence processing http://purl.obolibrary.org/obo/GO_0006618 CHEBI:17075 biolink:ChemicalSubstance 6-hydroxyhexano-6-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17075 chebi_ph7_3 CHEBI:32690 biolink:ChemicalSubstance D-argininium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32690 CHEBI:32691 biolink:ChemicalSubstance D-arginyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32691 GO:0006619 biolink:BiologicalProcess obsolete SRP-independent cotranslational protein-membrane targeting OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition. go-plus.json SRP-independent cotranslational membrane targeting|SRP-independent cotranslational protein-membrane targeting|ER translocation http://purl.obolibrary.org/obo/GO_0006619 CHEBI:17076 biolink:ChemicalSubstance streptomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17076 GO:0016190 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016190 GO:0016191 biolink:BiologicalProcess synaptic vesicle uncoating The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane. go-plus.json synaptic vesicle coat depolymerization|synaptic vesicle coat protein depolymerization http://purl.obolibrary.org/obo/GO_0016191 goslim_synapse GO:0016192 biolink:BiologicalProcess vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. go-plus.json vesicle transport|nonselective vesicle transport|protein sorting along secretory pathway|vesicular transport|vesicle trafficking http://purl.obolibrary.org/obo/GO_0016192 goslim_generic|goslim_pombe|goslim_chembl|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus GO:0016193 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016193 GO:0016187 biolink:BiologicalProcess obsolete synaptic vesicle internalization OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis. go-plus.json synaptic vesicle internalization http://purl.obolibrary.org/obo/GO_0016187 GO:0016188 biolink:BiologicalProcess synaptic vesicle maturation Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0016188 GO:0016189 biolink:BiologicalProcess synaptic vesicle to endosome fusion Fusion of a synaptic vesicle with an endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0016189 goslim_synapse GO:0016183 biolink:BiologicalProcess synaptic vesicle coating The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0016183 goslim_synapse GO:0016184 biolink:BiologicalProcess obsolete synaptic vesicle retrieval OBSOLETE. Return of a vesicle from the postsynaptic membrane to presynaptic membrane. go-plus.json synaptic vesicle retrieval http://purl.obolibrary.org/obo/GO_0016184 GO:0016185 biolink:BiologicalProcess synaptic vesicle budding from presynaptic endocytic zone membrane Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle. go-plus.json synaptic vesicle budding involved in synaptic vesicle endocytosis|synaptic vesicle budding from pre-synaptic membrane http://purl.obolibrary.org/obo/GO_0016185 goslim_synapse GO:0016186 biolink:BiologicalProcess obsolete synaptic vesicle fission OBSOLETE. Separation of a synaptic vesicle from the presynaptic membrane. go-plus.json synaptic vesicle fission http://purl.obolibrary.org/obo/GO_0016186 CHEBI:136061 biolink:ChemicalSubstance (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136061 chebi_ph7_3 CHEBI:4249 biolink:ChemicalSubstance D-tagatopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_4249 chebi_ph7_3 GO:0016198 biolink:BiologicalProcess axon choice point recognition The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth. go-plus.json http://purl.obolibrary.org/obo/GO_0016198 GO:0016199 biolink:BiologicalProcess axon midline choice point recognition The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline. go-plus.json http://purl.obolibrary.org/obo/GO_0016199 GO:0016194 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016194 GO:0016195 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016195 GO:0016196 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016196 GO:0016197 biolink:BiologicalProcess endosomal transport The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane. go-plus.json endosome transport|endosome localisation|endosome localization http://purl.obolibrary.org/obo/GO_0016197 goslim_yeast GO:0016170 biolink:MolecularActivity interleukin-15 receptor binding Binding to an interleukin-15 receptor. go-plus.json interleukin-15 receptor ligand|IL-15 http://purl.obolibrary.org/obo/GO_0016170 GO:0016171 biolink:MolecularActivity obsolete cell surface antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json cell surface antigen http://purl.obolibrary.org/obo/GO_0016171 GO:0016169 biolink:MolecularActivity bacteriochlorophyll c binding Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0016169 GO:0016165 biolink:MolecularActivity linoleate 13S-lipoxygenase activity Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate. MetaCyc:LIPOXYGENASE-RXN|RHEA:22780|EC:1.13.11.12 go-plus.json carotene oxidase activity|fat oxidase activity|lipoxydase activity|lipoperoxidase activity|lipoxygenase activity|lipoxidase activity|lionoleate:O2 oxidoreductase activity|linoleate:oxygen 13-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0016165 GO:0016166 biolink:MolecularActivity phytoene dehydrogenase activity Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene. go-plus.json http://purl.obolibrary.org/obo/GO_0016166 GO:0016167 biolink:MolecularActivity glial cell-derived neurotrophic factor receptor activity Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json GDNF receptor activity|glial cell line-derived neurotrophic factor receptor activity http://purl.obolibrary.org/obo/GO_0016167 GO:0016168 biolink:MolecularActivity chlorophyll binding Binding to a chlorophyll; a compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment. go-plus.json http://purl.obolibrary.org/obo/GO_0016168 GO:0016161 biolink:MolecularActivity beta-amylase activity Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains. MetaCyc:RXN-1827|EC:3.2.1.2|MetaCyc:RXN-12279 go-plus.json beta amylase activity|glycogenase activity|1,4-alpha-D-glucan maltohydrolase activity|saccharogen amylase activity http://purl.obolibrary.org/obo/GO_0016161 GO:0016162 biolink:MolecularActivity cellulose 1,4-beta-cellobiosidase activity Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains. EC:3.2.1.91|MetaCyc:3.2.1.91-RXN go-plus.json exocellobiohydrolase activity|cellobiosidase activity|avicelase activity|C1 cellulase activity|cellobiohydrolase I|exo-cellobiohydrolase activity|beta-1,4-glucan cellobiohydrolase activity|1,4-beta-D-glucan cellobiohydrolase activity|exo-1,4-beta-D-glucanase activity|1,4-beta-cellobiohydrolase activity|CBH 1|exoglucanase activity|1,4-beta-glucan cellobiosidase activity|beta-1,4-glucan cellobiosylhydrolase activity|cellobiohydrolase activity|exo-beta-1,4-glucan cellobiohydrolase activity http://purl.obolibrary.org/obo/GO_0016162 GO:0016163 biolink:MolecularActivity nitrogenase activity Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. UM-BBD_enzymeID:e0395|RHEA:21448|EC:1.18.6.1|MetaCyc:NITROGENASE-RXN go-plus.json reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity|iron-iron nitrogenase activity|vanadium-iron nitrogenase activity|molybdenum-iron nitrogenase activity http://purl.obolibrary.org/obo/GO_0016163 GO:0016164 biolink:MolecularActivity obsolete Mo-molybdopterin oxidoreductase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json molybdopterin oxidoreductase activity|Mo-molybdopterin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0016164 GO:0016180 biolink:BiologicalProcess snRNA processing Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0016180 GO:0016181 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016181 GO:0016182 biolink:BiologicalProcess synaptic vesicle budding from endosome Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes. go-plus.json endosome to synaptic vesicle budding|synaptic vesicle budding involved in synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_0016182 goslim_synapse GO:0031799 biolink:MolecularActivity type 2 metabotropic glutamate receptor binding Binding to a type 2 metabotropic glutamate receptor. go-plus.json type 2 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031799 GO:0031797 biolink:MolecularActivity type 2 metabotropic GABA receptor binding Binding to a type 2 metabotropic GABA receptor. go-plus.json type 2 metabotropic GABA receptor ligand http://purl.obolibrary.org/obo/GO_0031797 GO:0031798 biolink:MolecularActivity type 1 metabotropic glutamate receptor binding Binding to a type 1 metabotropic glutamate receptor. go-plus.json type 1 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031798 GO:0100001 biolink:BiologicalProcess regulation of skeletal muscle contraction by action potential Any action potential process that regulates skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0100001 GO:0100002 biolink:BiologicalProcess negative regulation of protein kinase activity by protein phosphorylation Any protein phosphorylation process that negatively regulates protein kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0100002 GO:0100003 biolink:BiologicalProcess obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport. go-plus.json http://purl.obolibrary.org/obo/GO_0100003 GO:0100004 biolink:BiologicalProcess obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization. go-plus.json http://purl.obolibrary.org/obo/GO_0100004 GO:0100005 biolink:BiologicalProcess obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100005 GO:0100006 biolink:BiologicalProcess obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport. go-plus.json http://purl.obolibrary.org/obo/GO_0100006 GO:0100007 biolink:BiologicalProcess obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100007 GO:0100008 biolink:BiologicalProcess regulation of fever generation by prostaglandin biosynthetic process Any prostaglandin biosynthetic process process that regulates fever generation. go-plus.json http://purl.obolibrary.org/obo/GO_0100008 GO:0100009 biolink:BiologicalProcess regulation of fever generation by prostaglandin secretion Any prostaglandin secretion process that regulates fever generation. go-plus.json http://purl.obolibrary.org/obo/GO_0100009 GO:0016176 biolink:MolecularActivity superoxide-generating NADPH oxidase activator activity Increases the activity of the enzyme superoxide-generating NADPH oxidase. go-plus.json neutrophil cytosol factor 2 http://purl.obolibrary.org/obo/GO_0016176 GO:0031795 biolink:MolecularActivity G protein-coupled GABA receptor binding Binding to a G protein-coupled (metabotropic) GABA receptor. go-plus.json metabotropic GABA receptor binding|GABAB receptor binding|G-protein coupled GABA receptor binding|metabotropic GABA receptor ligand http://purl.obolibrary.org/obo/GO_0031795 GO:0016177 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016177 GO:0031796 biolink:MolecularActivity type 1 metabotropic GABA receptor binding Binding to a type 1 metabotropic GABA receptor. go-plus.json type 1 metabotropic GABA receptor ligand http://purl.obolibrary.org/obo/GO_0031796 GO:0016178 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016178 GO:0031793 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031793 GO:0016179 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016179 GO:0031794 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031794 GO:0031791 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031791 GO:0016172 biolink:MolecularActivity obsolete antifreeze activity OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures. go-plus.json antifreeze activity http://purl.obolibrary.org/obo/GO_0016172 CHEBI:4222 biolink:ChemicalSubstance D-pantetheine 4'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4222 GO:0031792 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031792 GO:0016173 biolink:MolecularActivity obsolete ice nucleation inhibitor activity OBSOLETE. Inhibits the formation of ice crystals. go-plus.json ice nucleation inhibitor activity http://purl.obolibrary.org/obo/GO_0016173 GO:0016174 biolink:MolecularActivity NAD(P)H oxidase H2O2-forming activity Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide. Reactome:R-HSA-9698758|Reactome:R-HSA-5693681|EC:1.6.3.1 go-plus.json NAD(P)H:oxygen oxidoreductase activity|ThOX activity|thyroid oxidase 2 activity|thyroid NADPH oxidase activity|p138tox|NAD(P)H oxidase activity|NADPH oxidase|thyroid oxidase activity|THOX2 activity|dual oxidase activity http://purl.obolibrary.org/obo/GO_0016174 GO:0016175 biolink:MolecularActivity superoxide-generating NAD(P)H oxidase activity Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-. Reactome:R-HSA-6807557|EC:1.6.3.-|Reactome:R-HSA-5668718|Reactome:R-HSA-1222376|Reactome:R-HSA-5668629|Reactome:R-HSA-1236967|Reactome:R-HSA-6789092|Reactome:R-HSA-5668731|Reactome:R-HSA-9673797|Reactome:R-HSA-1497810|Reactome:R-HSA-5218841 go-plus.json cytochrome B-245 http://purl.obolibrary.org/obo/GO_0016175 GO:0031790 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031790 GO:0031788 biolink:MolecularActivity motilin receptor binding Binding to a motilin receptor. go-plus.json motilin receptor ligand http://purl.obolibrary.org/obo/GO_0031788 CHEBI:4280 biolink:ChemicalSubstance (2R,4S)-2,4-diaminopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4280 GO:0031789 biolink:MolecularActivity G protein-coupled acetylcholine receptor binding Binding to a G protein-coupled acetylcholine receptor. go-plus.json M1 muscarinic acetylcholine receptor ligand|M2 muscarinic acetylcholine receptor ligand|M3 muscarinic acetylcholine receptor ligand|M4 muscarinic acetylcholine receptor ligand|M5 muscarinic acetylcholine receptor ligand|muscarinic acetylcholine receptor binding|M5 muscarinic acetylcholine receptor binding|M4 muscarinic acetylcholine receptor binding|M3 muscarinic acetylcholine receptor binding|M2 muscarinic acetylcholine receptor binding|M1 muscarinic acetylcholine receptor binding|G-protein coupled acetylcholine receptor binding|muscarinic acetylcholine receptor ligand http://purl.obolibrary.org/obo/GO_0031789 GO:0031786 biolink:MolecularActivity type 1B melatonin receptor binding Binding to a type 1B melatonin receptor. go-plus.json type 1B melatonin receptor ligand http://purl.obolibrary.org/obo/GO_0031786 GO:0031787 biolink:MolecularActivity H9 melatonin receptor binding Binding to a H9 melatonin receptor. go-plus.json H9 melatonin receptor ligand http://purl.obolibrary.org/obo/GO_0031787 GO:0090129 biolink:BiologicalProcess positive regulation of synapse maturation Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0090129 GO:0090127 biolink:BiologicalProcess positive regulation of synapse maturation by synaptic transmission Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0090127 GO:0090128 biolink:BiologicalProcess regulation of synapse maturation Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0090128 goslim_synapse GO:0016147 biolink:MolecularActivity obsolete protein-synthesizing GTPase activity, elongation OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json protein-synthesizing GTPase activity, elongation http://purl.obolibrary.org/obo/GO_0016147 CHEBI:439819 biolink:ChemicalSubstance L-alpha-phenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_439819 GO:0016148 biolink:MolecularActivity obsolete protein-synthesizing GTPase activity, termination OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json protein-synthesizing GTPase activity, termination http://purl.obolibrary.org/obo/GO_0016148 GO:0016149 biolink:MolecularActivity translation release factor activity, codon specific A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site. go-plus.json http://purl.obolibrary.org/obo/GO_0016149 GO:0031784 biolink:MolecularActivity melatonin receptor binding Binding to a melatonin receptor. go-plus.json melatonin receptor ligand http://purl.obolibrary.org/obo/GO_0031784 GO:0090121 biolink:BiologicalProcess low-density lipoprotein particle disassembly involved in cholesterol transport The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport. go-plus.json http://purl.obolibrary.org/obo/GO_0090121 GO:0016143 biolink:BiologicalProcess S-glycoside metabolic process The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group. go-plus.json thioglycoside metabolism|S-glycoside metabolism|thioglycoside metabolic process http://purl.obolibrary.org/obo/GO_0016143 GO:0031785 biolink:MolecularActivity type 1A melatonin receptor binding Binding to a type 1A melatonin receptor. go-plus.json type 1A melatonin receptor ligand http://purl.obolibrary.org/obo/GO_0031785 GO:0090122 biolink:BiologicalProcess cholesterol ester hydrolysis involved in cholesterol transport The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport. go-plus.json http://purl.obolibrary.org/obo/GO_0090122 GO:0016144 biolink:BiologicalProcess S-glycoside biosynthetic process The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group. go-plus.json S-glycoside anabolism|S-glycoside synthesis|thioglycoside biosynthetic process|S-glycoside biosynthesis|thioglycoside biosynthesis|S-glycoside formation http://purl.obolibrary.org/obo/GO_0016144 GO:0016145 biolink:BiologicalProcess S-glycoside catabolic process The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group. go-plus.json thioglycoside catabolic process|thioglycoside catabolism|S-glycoside catabolism|S-glycoside degradation|S-glycoside breakdown http://purl.obolibrary.org/obo/GO_0016145 GO:0031782 biolink:MolecularActivity type 4 melanocortin receptor binding Binding to a type 4 melanocortin receptor. go-plus.json type 4 melanocortin receptor ligand http://purl.obolibrary.org/obo/GO_0031782 GO:0090120 biolink:BiologicalProcess lysosome to ER cholesterol transport The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum. go-plus.json lysosome to endoplasmic reticulum cholesterol transport http://purl.obolibrary.org/obo/GO_0090120 GO:0016146 biolink:MolecularActivity obsolete protein-synthesizing GTPase activity, initiation OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json protein-synthesizing GTPase activity, initiation http://purl.obolibrary.org/obo/GO_0016146 GO:0031783 biolink:MolecularActivity type 5 melanocortin receptor binding Binding to a type 5 melanocortin receptor. go-plus.json type 5 melanocortin receptor ligand http://purl.obolibrary.org/obo/GO_0031783 GO:0031780 biolink:MolecularActivity corticotropin hormone receptor binding Binding to a corticotropin hormone receptor. go-plus.json ACTH receptor binding|corticotropin receptor binding|adrenocorticotropic hormone receptor ligand|adrenocorticotropin receptor binding|adrenocorticotropin hormone receptor binding http://purl.obolibrary.org/obo/GO_0031780 GO:0090125 biolink:BiologicalProcess cell-cell adhesion involved in synapse maturation The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation. go-plus.json trans-synaptic adhesion http://purl.obolibrary.org/obo/GO_0090125 GO:0090126 biolink:BiologicalProcess protein-containing complex assembly involved in synapse maturation The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation. go-plus.json protein complex assembly involved in synapse maturation http://purl.obolibrary.org/obo/GO_0090126 GO:0031781 biolink:MolecularActivity type 3 melanocortin receptor binding Binding to a type 3 melanocortin receptor. go-plus.json type 3 melanocortin receptor ligand http://purl.obolibrary.org/obo/GO_0031781 GO:0016140 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016140 GO:0090123 biolink:CellularComponent lysosomal glycocalyx The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes. go-plus.json http://purl.obolibrary.org/obo/GO_0090123 GO:0016141 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016141 GO:0090124 biolink:BiologicalProcess N-4 methylation of cytosine The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0090124 GO:0016142 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016142 GO:0031779 biolink:MolecularActivity melanocortin receptor binding Binding to a melanocortin receptor. go-plus.json melanocortin receptor ligand http://purl.obolibrary.org/obo/GO_0031779 GO:0016160 biolink:MolecularActivity amylase activity Catalysis of the hydrolysis of amylose or an amylose derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0016160 GO:0031777 biolink:MolecularActivity type 1 melanin-concentrating hormone receptor binding Binding to a type 1 melanin-concentrating hormone receptor. go-plus.json type 1 melanin-concentrating hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031777 GO:0031778 biolink:MolecularActivity type 2 melanin-concentrating hormone receptor binding Binding to a type 2 melanin-concentrating hormone receptor. go-plus.json type 2 melanin-concentrating hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031778 GO:0031775 biolink:MolecularActivity lutropin-choriogonadotropic hormone receptor binding Binding to a lutropin-choriogonadotropic hormone receptor. go-plus.json lutropin-choriogonadotropic hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031775 GO:0031776 biolink:MolecularActivity melanin-concentrating hormone receptor binding Binding to a melanin-concentrating hormone receptor. go-plus.json melanin-concentrating hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031776 GO:0090138 biolink:BiologicalProcess regulation of actin cytoskeleton organization by cell-cell adhesion Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. go-plus.json regulation of actin cytoskeleton organisation by cell-cell adhesion http://purl.obolibrary.org/obo/GO_0090138 GO:0090139 biolink:BiologicalProcess mitochondrial DNA packaging Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure. go-plus.json http://purl.obolibrary.org/obo/GO_0090139 GO:0016158 biolink:MolecularActivity 3-phytase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate. EC:3.1.3.8|MetaCyc:RXN0-1001|RHEA:16989 go-plus.json phytate 1-phosphatase activity|phytase activity|myo-inositol-hexaphosphate 3-phosphohydrolase activity|phytate 3-phosphatase activity|myo-inositol-hexakisphosphate 3-phosphohydrolase activity|1-phytase activity http://purl.obolibrary.org/obo/GO_0016158 GO:0016159 biolink:MolecularActivity muconolactone delta-isomerase activity Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate. EC:5.3.3.4|MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN|RHEA:12348 go-plus.json muconolactone isomerase activity|5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity|muconolactone D-isomerase activity http://purl.obolibrary.org/obo/GO_0016159 GO:0031773 biolink:MolecularActivity kisspeptin receptor binding Binding to a kisspeptin receptor. go-plus.json hypogonadotropin-1 receptor binding|KiSS-1 receptor binding|hOT7T175 receptor binding|metastin receptor binding|kisspeptin receptor ligand|G-protein coupled receptor 54 binding http://purl.obolibrary.org/obo/GO_0031773 GO:0090132 biolink:BiologicalProcess epithelium migration The process in which the population of cells that make up an epithelium undergo directed movement. go-plus.json http://purl.obolibrary.org/obo/GO_0090132 GO:0016154 biolink:MolecularActivity pyrimidine-nucleoside phosphorylase activity Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. EC:2.4.2.2|MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN go-plus.json pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity|Py-NPase activity http://purl.obolibrary.org/obo/GO_0016154 GO:0031774 biolink:MolecularActivity leukotriene receptor binding Binding to a leukotriene receptor. go-plus.json leukotriene receptor ligand http://purl.obolibrary.org/obo/GO_0031774 GO:0016155 biolink:MolecularActivity formyltetrahydrofolate dehydrogenase activity Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH. EC:1.5.1.6|RHEA:10180|MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN|KEGG_REACTION:R00941 go-plus.json 10-formyltetrahydrofolate:NADP+ oxidoreductase activity|10-formyl-H2PtGlu:NADP oxidoreductase activity|10-formyl-H4folate dehydrogenase activity|N10-formyltetrahydrofolate dehydrogenase activity|10-formyl tetrahydrofolate:NADP oxidoreductase activity|10-formyltetrahydrofolate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0016155 GO:0090133 biolink:BiologicalProcess mesendoderm migration The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0090133 GO:0090130 biolink:BiologicalProcess tissue migration The process in which the population of cells that make up a tissue undergo directed movement. go-plus.json http://purl.obolibrary.org/obo/GO_0090130 GO:0016156 biolink:MolecularActivity fumarate reductase (NADH) activity Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH. EC:1.3.1.6|RHEA:18281|MetaCyc:FUMARATE-REDUCTASE-NADH-RXN|KEGG_REACTION:R00402 go-plus.json NADH-fumarate reductase activity|NADH-dependent fumarate reductase activity|succinate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0016156 GO:0031771 biolink:MolecularActivity type 1 hypocretin receptor binding Binding to a type 1 hypocretin receptor. go-plus.json type 1 hypocretin receptor ligand|type 1 orexin receptor binding http://purl.obolibrary.org/obo/GO_0031771 GO:0090131 biolink:BiologicalProcess mesenchyme migration The process in which the population of cells that make up a mesenchyme undergo directed movement. go-plus.json http://purl.obolibrary.org/obo/GO_0090131 GO:0016157 biolink:MolecularActivity sucrose synthase activity Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose. MetaCyc:SUCROSE-SYNTHASE-RXN|EC:2.4.1.13 go-plus.json uridine diphosphoglucose-fructose glucosyltransferase activity|sucrose-uridine diphosphate glucosyltransferase activity|sucrose-UDP glucosyltransferase activity|UDPglucose-fructose glucosyltransferase activity|UDP-glucose-fructose glucosyltransferase activity|sucrose synthetase activity|NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0016157 GO:0031772 biolink:MolecularActivity type 2 hypocretin receptor binding Binding to a type 2 hypocretin receptor. go-plus.json type 2 hypocretin receptor ligand|type 2 orexin receptor binding http://purl.obolibrary.org/obo/GO_0031772 GO:0016150 biolink:MolecularActivity translation release factor activity, codon nonspecific A translation release factor that is not specific to particular codons; binds to guanine nucleotides. go-plus.json http://purl.obolibrary.org/obo/GO_0016150 GO:0090136 biolink:BiologicalProcess epithelial cell-cell adhesion The attachment of an epithelial cell to another epithelial cell via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0090136 GO:0016151 biolink:MolecularActivity nickel cation binding Binding to a nickel (Ni) cation. go-plus.json Ni binding|nickel binding http://purl.obolibrary.org/obo/GO_0016151 GO:0090137 biolink:BiologicalProcess epithelial cell-cell adhesion involved in epithelium migration The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration. go-plus.json http://purl.obolibrary.org/obo/GO_0090137 GO:0031770 biolink:MolecularActivity growth hormone-releasing hormone receptor binding Binding to a growth hormone-releasing hormone receptor. go-plus.json growth hormone-releasing hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031770 GO:0016152 biolink:MolecularActivity mercury (II) reductase activity Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH. EC:1.16.1.1|MetaCyc:MERCURY-II-REDUCTASE-RXN|KEGG_REACTION:R02807|UM-BBD_reactionID:r0406|RHEA:23856 go-plus.json mercury reductase activity|reduced NADP:mercuric ion oxidoreductase activity|mercury(II) reductase activity|mer A|mercuric reductase activity|Hg:NADP+ oxidoreductase activity|mercuric ion reductase activity|mercurate(II) reductase activity http://purl.obolibrary.org/obo/GO_0016152 GO:0090134 biolink:BiologicalProcess cell migration involved in mesendoderm migration The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0090134 GO:0016153 biolink:MolecularActivity urocanate hydratase activity Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O. RHEA:13101|KEGG_REACTION:R02914|EC:4.2.1.49|MetaCyc:UROCANATE-HYDRATASE-RXN|Reactome:R-HSA-70903 go-plus.json 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)|imidazolonepropionate hydrolase activity|urocanase activity|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0016153 GO:0090135 biolink:BiologicalProcess actin filament branching The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0090135 GO:0031768 biolink:MolecularActivity ghrelin receptor binding Binding to a ghrelin receptor. go-plus.json type 1 growth hormone secretagogue GH-releasing peptide receptor binding|ghrelin receptor ligand http://purl.obolibrary.org/obo/GO_0031768 GO:0031769 biolink:MolecularActivity glucagon receptor binding Binding to a glucagon receptor. go-plus.json glucagon receptor ligand http://purl.obolibrary.org/obo/GO_0031769 GO:0031766 biolink:MolecularActivity type 3 galanin receptor binding Binding to a type 3 galanin receptor. go-plus.json type 3 galanin receptor ligand http://purl.obolibrary.org/obo/GO_0031766 GO:0031767 biolink:MolecularActivity gastric inhibitory polypeptide receptor binding Binding to a gastric inhibitory polypeptide receptor. go-plus.json gastric inhibitory polypeptide receptor ligand http://purl.obolibrary.org/obo/GO_0031767 GO:0031764 biolink:MolecularActivity type 1 galanin receptor binding Binding to a type 1 galanin receptor. go-plus.json type 1 galanin receptor ligand http://purl.obolibrary.org/obo/GO_0031764 GO:0031765 biolink:MolecularActivity type 2 galanin receptor binding Binding to a type 2 galanin receptor. go-plus.json type 2 galanin receptor ligand http://purl.obolibrary.org/obo/GO_0031765 GO:0090107 biolink:BiologicalProcess regulation of high-density lipoprotein particle assembly Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0090107 GO:0016129 biolink:BiologicalProcess phytosteroid biosynthetic process The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi. go-plus.json phytosteroid anabolism|phytosteroid synthesis|phytosteroid formation|phytosteroid biosynthesis http://purl.obolibrary.org/obo/GO_0016129 GO:0090108 biolink:BiologicalProcess positive regulation of high-density lipoprotein particle assembly Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0090108 GO:0090105 biolink:BiologicalProcess pancreatic E cell development The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0090105 GO:0090106 biolink:BiologicalProcess pancreatic E cell fate commitment The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090106 GO:0016125 biolink:BiologicalProcess sterol metabolic process The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json sterol metabolism http://purl.obolibrary.org/obo/GO_0016125 GO:0016126 biolink:BiologicalProcess sterol biosynthetic process The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. MetaCyc:PWY-2541 go-plus.json sterol synthesis|sterol formation|sterol anabolism|sterol biosynthesis http://purl.obolibrary.org/obo/GO_0016126 GO:0090109 biolink:BiologicalProcess regulation of cell-substrate junction assembly Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0090109 GO:0016127 biolink:BiologicalProcess sterol catabolic process The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json sterol degradation|sterol breakdown|sterol catabolism http://purl.obolibrary.org/obo/GO_0016127 GO:0016128 biolink:BiologicalProcess phytosteroid metabolic process The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi. go-plus.json phytosteroid metabolism http://purl.obolibrary.org/obo/GO_0016128 GO:0016121 biolink:BiologicalProcess carotene catabolic process The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids. go-plus.json carotene catabolism|carotene degradation|carotene breakdown http://purl.obolibrary.org/obo/GO_0016121 GO:0031762 biolink:MolecularActivity follicle-stimulating hormone receptor binding Binding to a follicle-stimulating hormone receptor. go-plus.json follicle stimulating hormone receptor binding|follicle stimulating hormone receptor ligand|FSH receptor binding http://purl.obolibrary.org/obo/GO_0031762 CHEBI:4251 biolink:ChemicalSubstance D-tagatofuranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4251 GO:0016122 biolink:BiologicalProcess xanthophyll metabolic process The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids. go-plus.json xanthophyll metabolism http://purl.obolibrary.org/obo/GO_0016122 GO:0031763 biolink:MolecularActivity galanin receptor binding Binding to a galanin receptor. go-plus.json galanin receptor ligand http://purl.obolibrary.org/obo/GO_0031763 GO:0090100 biolink:BiologicalProcess positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. go-plus.json positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway http://purl.obolibrary.org/obo/GO_0090100 GO:0016123 biolink:BiologicalProcess xanthophyll biosynthetic process The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids. go-plus.json xanthophyll synthesis|xanthophyll formation|xanthophyll anabolism|xanthophyll biosynthesis http://purl.obolibrary.org/obo/GO_0016123 GO:0031760 biolink:MolecularActivity Edg-7 lysophosphatidic acid receptor binding Binding to an Edg-7 lysophosphatidic acid receptor. go-plus.json LPA3 receptor binding|Edg-7 lysophosphatidic acid receptor ligand http://purl.obolibrary.org/obo/GO_0031760 GO:0016124 biolink:BiologicalProcess xanthophyll catabolic process The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids. go-plus.json xanthophyll degradation|xanthophyll breakdown|xanthophyll catabolism http://purl.obolibrary.org/obo/GO_0016124 GO:0031761 biolink:MolecularActivity fMet-Leu-Phe receptor binding Binding to a fMet-Leu-Phe receptor. go-plus.json fMet-Leu-Phe receptor ligand|N-formyl peptide receptor binding http://purl.obolibrary.org/obo/GO_0031761 CHEBI:4250 biolink:ChemicalSubstance D-tagatofuranose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4250 GO:0090103 biolink:BiologicalProcess cochlea morphogenesis The process in which the cochlea is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0090103 GO:0090104 biolink:BiologicalProcess pancreatic epsilon cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin. go-plus.json pancreatic E cell differentiation http://purl.obolibrary.org/obo/GO_0090104 GO:0090101 biolink:BiologicalProcess negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. go-plus.json negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway http://purl.obolibrary.org/obo/GO_0090101 GO:0016120 biolink:BiologicalProcess carotene biosynthetic process The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids. go-plus.json carotene anabolism|carotene synthesis|carotene formation|carotene biosynthesis http://purl.obolibrary.org/obo/GO_0016120 GO:0090102 biolink:BiologicalProcess cochlea development The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. go-plus.json http://purl.obolibrary.org/obo/GO_0090102 GO:0031759 biolink:MolecularActivity Edg-6 sphingosine 1-phosphate receptor binding Binding to an Edg-6 sphingosine 1-phosphate receptor. go-plus.json Edg-6 sphingosine 1-phosphate receptor ligand http://purl.obolibrary.org/obo/GO_0031759 GO:0031757 biolink:MolecularActivity Edg-4 lysophosphatidic acid receptor binding Binding to an Edg-4 lysophosphatidic acid receptor. go-plus.json Edg-4 lysophosphatidic acid receptor ligand|LPA2 receptor binding http://purl.obolibrary.org/obo/GO_0031757 GO:0031758 biolink:MolecularActivity Edg-5 sphingosine 1-phosphate receptor binding Binding to an Edg-5 sphingosine 1-phosphate receptor. go-plus.json Edg-5 sphingosine 1-phosphate receptor ligand http://purl.obolibrary.org/obo/GO_0031758 GO:0031755 biolink:MolecularActivity Edg-2 lysophosphatidic acid receptor binding Binding to an Edg-2 lysophosphatidic acid receptor. go-plus.json Edg-2 lysophosphatidic acid receptor ligand|LPA1 receptor binding http://purl.obolibrary.org/obo/GO_0031755 GO:0031756 biolink:MolecularActivity Edg-3 sphingosine 1-phosphate receptor binding Binding to an Edg-3 sphingosine 1-phosphate receptor. go-plus.json Edg-3 sphingosine 1-phosphate receptor ligand http://purl.obolibrary.org/obo/GO_0031756 GO:0031753 biolink:MolecularActivity endothelial differentiation G protein-coupled receptor binding Binding to an endothelial differentiation G protein-coupled receptor. go-plus.json endothelial differentiation G-protein coupled receptor ligand|endothelial differentiation G-protein coupled receptor binding http://purl.obolibrary.org/obo/GO_0031753 GO:0031754 biolink:MolecularActivity Edg-1 sphingosine 1-phosphate receptor binding Binding to an Edg-1 sphingosine 1-phosphate receptor. go-plus.json Edg-1 sphingosine 1-phosphate receptor ligand http://purl.obolibrary.org/obo/GO_0031754 GO:0090118 biolink:BiologicalProcess receptor-mediated endocytosis involved in cholesterol transport A receptor-mediated endocytosis process involved in intracellular cholesterol transport. go-plus.json receptor-mediated endocytosis involved in intracellular cholesterol transport|receptor-mediated endocytosis of LDL|receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport http://purl.obolibrary.org/obo/GO_0090118 GO:0090119 biolink:BiologicalProcess vesicle-mediated cholesterol transport The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0090119 GO:0090116 biolink:BiologicalProcess C-5 methylation of cytosine The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0090116 GO:0090117 biolink:BiologicalProcess endosome to lysosome transport of low-density lipoprotein particle The directed movement of low-density lipoprotein particle from endosomes to lysosomes. go-plus.json endosome to lysosome transport of LDL http://purl.obolibrary.org/obo/GO_0090117 GO:0016136 biolink:BiologicalProcess saponin catabolic process The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection. go-plus.json saponin degradation|saponin catabolism|saponin breakdown http://purl.obolibrary.org/obo/GO_0016136 GO:0016137 biolink:BiologicalProcess glycoside metabolic process The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. go-plus.json O-glycoside metabolic process|glycoside metabolism|O-glycoside metabolism http://purl.obolibrary.org/obo/GO_0016137 GO:0016138 biolink:BiologicalProcess glycoside biosynthetic process The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. go-plus.json glycoside anabolism|O-glycoside synthesis|glycoside synthesis|O-glycoside formation|glycoside formation|glycoside biosynthesis|O-glycoside biosynthetic process|O-glycoside biosynthesis|O-glycoside anabolism http://purl.obolibrary.org/obo/GO_0016138 GO:0016139 biolink:BiologicalProcess glycoside catabolic process The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. go-plus.json O-glycoside degradation|glycoside degradation|O-glycoside breakdown|glycoside catabolism|glycoside breakdown|O-glycoside catabolism|O-glycoside catabolic process http://purl.obolibrary.org/obo/GO_0016139 GO:0090110 biolink:BiologicalProcess COPII-coated vesicle cargo loading The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi. go-plus.json COPII coat-cargo complex assembly|cargo selection into COPII-coated vesicle|cargo loading into COPII-coated vesicle|cargo loading into COPII vesicle http://purl.obolibrary.org/obo/GO_0090110 GO:0016132 biolink:BiologicalProcess brassinosteroid biosynthetic process The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects. MetaCyc:PWY-2582|MetaCyc:PWY-699 go-plus.json brassinosteroid biosynthesis|brassinosteroid anabolism|brassinosteroid synthesis|brassinosteroid formation http://purl.obolibrary.org/obo/GO_0016132 GO:0031751 biolink:MolecularActivity D4 dopamine receptor binding Binding to a D4 dopamine receptor. go-plus.json D4 dopamine receptor ligand http://purl.obolibrary.org/obo/GO_0031751 GO:0016133 biolink:BiologicalProcess brassinosteroid catabolic process The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects. go-plus.json brassinosteroid catabolism|brassinosteroid degradation|brassinosteroid breakdown http://purl.obolibrary.org/obo/GO_0016133 GO:0031752 biolink:MolecularActivity D5 dopamine receptor binding Binding to a D5 dopamine receptor. go-plus.json D1B dopamine receptor binding|D5 dopamine receptor ligand http://purl.obolibrary.org/obo/GO_0031752 GO:0090111 biolink:BiologicalProcess regulation of COPII vesicle uncoating Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released. go-plus.json http://purl.obolibrary.org/obo/GO_0090111 GO:0016134 biolink:BiologicalProcess saponin metabolic process The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection. go-plus.json saponin metabolism http://purl.obolibrary.org/obo/GO_0016134 GO:0031750 biolink:MolecularActivity D3 dopamine receptor binding Binding to a D3 dopamine receptor. go-plus.json D3 dopamine receptor ligand http://purl.obolibrary.org/obo/GO_0031750 GO:0016135 biolink:BiologicalProcess saponin biosynthetic process The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection. go-plus.json saponin biosynthesis|saponin anabolism|saponin synthesis|saponin formation http://purl.obolibrary.org/obo/GO_0016135 GO:0090114 biolink:BiologicalProcess COPII-coated vesicle budding The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle. go-plus.json ER vesicle budding|COPII vesicle budding|ER exit http://purl.obolibrary.org/obo/GO_0090114 GO:0090115 biolink:BiologicalProcess obsolete C-5 methylation on cytosine involved in chromatin silencing OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing. go-plus.json http://purl.obolibrary.org/obo/GO_0090115 GO:0016130 biolink:BiologicalProcess phytosteroid catabolic process The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi. go-plus.json phytosteroid degradation|phytosteroid breakdown|phytosteroid catabolism http://purl.obolibrary.org/obo/GO_0016130 GO:0090112 biolink:BiologicalProcess COPII vesicle uncoating The process in which COPII vesicle coat proteins are disassembled, and released. go-plus.json http://purl.obolibrary.org/obo/GO_0090112 GO:0016131 biolink:BiologicalProcess brassinosteroid metabolic process The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects. go-plus.json brassinosteroid metabolism http://purl.obolibrary.org/obo/GO_0016131 GO:0090113 biolink:BiologicalProcess regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0090113 GO:0100050 biolink:BiologicalProcess obsolete negative regulation of mating type switching by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates mating type switching. go-plus.json http://purl.obolibrary.org/obo/GO_0100050 GO:0100051 biolink:BiologicalProcess obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates meiotic nuclear division. go-plus.json http://purl.obolibrary.org/obo/GO_0100051 GO:0100052 biolink:BiologicalProcess obsolete negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates G1/S transition of mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0100052 GO:0100053 biolink:BiologicalProcess obsolete positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfate assimilation. go-plus.json http://purl.obolibrary.org/obo/GO_0100053 CHEBI:81559 biolink:ChemicalSubstance resolvin E1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_81559 GO:0100054 biolink:BiologicalProcess obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates flocculation via cell wall protein-carbohydrate interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0100054 GO:0100055 biolink:BiologicalProcess obsolete positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylserine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100055 GO:0100056 biolink:BiologicalProcess obsolete negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylserine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100056 GO:0100057 biolink:BiologicalProcess obsolete regulation of phenotypic switching by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates phenotypic switching. go-plus.json http://purl.obolibrary.org/obo/GO_0100057 GO:0100058 biolink:BiologicalProcess obsolete positive regulation of phenotypic switching by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phenotypic switching. go-plus.json http://purl.obolibrary.org/obo/GO_0100058 GO:0100059 biolink:BiologicalProcess obsolete negative regulation of phenotypic switching by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phenotypic switching. go-plus.json http://purl.obolibrary.org/obo/GO_0100059 CHEBI:81551 biolink:ChemicalSubstance bacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_81551 CHEBI:81552 biolink:ChemicalSubstance bacteriochlorophyllide c go-plus.json http://purl.obolibrary.org/obo/CHEBI_81552 GO:0100060 biolink:MolecularActivity obsolete negative regulation of SREBP signaling pathway by DNA binding OBSOLETE. Any DNA binding that negatively regulates SREBP signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0100060 GO:0100061 biolink:BiologicalProcess obsolete negative regulation of SREBP signaling pathway by transcription factor catabolic process OBSOLETE. Any transcription factor catabolic process process that negatively regulates SREBP signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0100061 GO:0100062 biolink:BiologicalProcess obsolete positive regulation of SREBP signaling pathway by transcription factor catabolic process OBSOLETE. Any transcription factor catabolic process process that positively_regulates SREBP signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0100062 GO:0100063 biolink:BiologicalProcess obsolete regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_0100063 GO:0100064 biolink:BiologicalProcess obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0100064 GO:0100065 biolink:BiologicalProcess obsolete negative regulation of leucine import by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates leucine import. go-plus.json http://purl.obolibrary.org/obo/GO_0100065 GO:0100066 biolink:BiologicalProcess obsolete negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates induction of conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0100066 GO:0100067 biolink:BiologicalProcess positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0100067 GO:0100068 biolink:BiologicalProcess obsolete positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pyrimidine-containing compound salvage. go-plus.json http://purl.obolibrary.org/obo/GO_0100068 GO:0100069 biolink:BiologicalProcess obsolete negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates neuron apoptotic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100069 CHEBI:81567 biolink:ChemicalSubstance thyroid stimulating hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_81567 CHEBI:81564 biolink:ChemicalSubstance resolvin D1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_81564 CHEBI:81565 biolink:ChemicalSubstance resolvin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_81565 CHEBI:81562 biolink:ChemicalSubstance 5S-Hydroperoxy-18R-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_81562 CHEBI:81563 biolink:ChemicalSubstance 18(R)-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_81563 GO:0100070 biolink:BiologicalProcess obsolete obsolete regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fatty acid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100070 NCBITaxon:207245 biolink:OrganismalEntity Fornicata go-plus.json Diplomonadida group http://purl.obolibrary.org/obo/NCBITaxon_207245 OBO:pato#has_cross_section biolink:OntologyClass has_cross_section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. has_cross_section go-plus.json http://purl.obolibrary.org/obo/pato#has_cross_section GO:0100010 biolink:BiologicalProcess positive regulation of fever generation by prostaglandin biosynthetic process Any prostaglandin biosynthetic process process that positively_regulates fever generation. go-plus.json http://purl.obolibrary.org/obo/GO_0100010 GO:0100011 biolink:BiologicalProcess positive regulation of fever generation by prostaglandin secretion Any prostaglandin secretion process that positively_regulates fever generation. go-plus.json http://purl.obolibrary.org/obo/GO_0100011 GO:0100012 biolink:BiologicalProcess regulation of heart induction by canonical Wnt signaling pathway Any canonical Wnt signaling pathway process that regulates heart induction. go-plus.json http://purl.obolibrary.org/obo/GO_0100012 GO:0100013 biolink:BiologicalProcess obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation. go-plus.json http://purl.obolibrary.org/obo/GO_0100013 GO:0100014 biolink:BiologicalProcess obsolete positive regulation of mating type switching by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates mating type switching. go-plus.json http://purl.obolibrary.org/obo/GO_0100014 GO:0100015 biolink:BiologicalProcess obsolete positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates inositol biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100015 GO:0100016 biolink:BiologicalProcess obsolete regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100016 GO:0100017 biolink:BiologicalProcess obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates single organismal cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0100017 GO:0100018 biolink:BiologicalProcess obsolete regulation of glucose import by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates glucose import. go-plus.json http://purl.obolibrary.org/obo/GO_0100018 GO:0100019 biolink:BiologicalProcess obsolete regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0100019 GO:0100020 biolink:BiologicalProcess obsolete regulation of transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport. go-plus.json http://purl.obolibrary.org/obo/GO_0100020 GO:0100021 biolink:BiologicalProcess obsolete regulation of iron ion transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates iron ion transport. go-plus.json regulation of iron ion import by transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0100021 GO:0100022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0100022 GO:0100023 biolink:BiologicalProcess obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division. go-plus.json http://purl.obolibrary.org/obo/GO_0100023 NCBITaxon:28376 biolink:OrganismalEntity Anolis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_28376 GO:0100024 biolink:BiologicalProcess obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100024 GO:0100025 biolink:BiologicalProcess obsolete negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular amino acid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100025 GO:0100026 biolink:BiologicalProcess positive regulation of DNA repair by transcription from RNA polymerase II promoter Any transcription from RNA polymerase II promoter process that positively regulates DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0100026 GO:0100027 biolink:BiologicalProcess obsolete regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0100027 NCBITaxon:28377 biolink:OrganismalEntity Anolis carolinensis go-plus.json green anole|Carolina anole http://purl.obolibrary.org/obo/NCBITaxon_28377 GO:0100028 biolink:BiologicalProcess obsolete regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0100028 GO:0100029 biolink:BiologicalProcess obsolete regulation of histone modification by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone modification. go-plus.json http://purl.obolibrary.org/obo/GO_0100029 GO:0100030 biolink:BiologicalProcess obsolete regulation of histone acetylation by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_0100030 GO:0100031 biolink:BiologicalProcess obsolete regulation of histone methylation by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0100031 GO:0100032 biolink:BiologicalProcess obsolete positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phospholipid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100032 GO:0100033 biolink:BiologicalProcess obsolete regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0100033 GO:0100034 biolink:BiologicalProcess obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates 4,6-pyruvylated galactose residue biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100034 GO:0100035 biolink:BiologicalProcess obsolete negative regulation of transmembrane transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_0100035 GO:0100036 biolink:BiologicalProcess obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates purine nucleotide biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100036 GO:0100037 biolink:BiologicalProcess obsolete positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates cellular alcohol catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100037 GO:0100038 biolink:BiologicalProcess obsolete regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cellular response to oxidative stress. go-plus.json http://purl.obolibrary.org/obo/GO_0100038 GO:0100039 biolink:BiologicalProcess obsolete regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100039 CHEBI:136065 biolink:ChemicalSubstance 1-aci-nitro-omega-(methylsulfanyl)alkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_136065 chebi_ph7_3 CHEBI:136067 biolink:ChemicalSubstance 3-aci-nitropropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136067 chebi_ph7_3 GO:0100040 biolink:BiologicalProcess obsolete negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates invasive growth in response to glucose limitation. go-plus.json http://purl.obolibrary.org/obo/GO_0100040 GO:0100041 biolink:BiologicalProcess obsolete positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pseudohyphal growth. go-plus.json http://purl.obolibrary.org/obo/GO_0100041 GO:0100042 biolink:BiologicalProcess obsolete negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates pseudohyphal growth. go-plus.json http://purl.obolibrary.org/obo/GO_0100042 GO:0100043 biolink:BiologicalProcess obsolete negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular response to alkaline pH. go-plus.json http://purl.obolibrary.org/obo/GO_0100043 GO:0100044 biolink:BiologicalProcess obsolete negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular hyperosmotic salinity response. go-plus.json http://purl.obolibrary.org/obo/GO_0100044 GO:0100045 biolink:BiologicalProcess negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter Any transcription from RNA polymerase II promoter process that negatively regulates arginine catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100045 GO:0100046 biolink:BiologicalProcess obsolete positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates arginine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100046 GO:0100047 biolink:BiologicalProcess obsolete negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates inositol biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100047 GO:0100048 biolink:BiologicalProcess obsolete positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylcholine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100048 GO:0100049 biolink:BiologicalProcess obsolete negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylcholine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0100049 CHEBI:136078 biolink:ChemicalSubstance 4-O-[di(2R)-1-glycerylphosphono]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136078 GO:0006704 biolink:BiologicalProcess glucocorticoid biosynthetic process The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. go-plus.json glucocorticoid anabolism|glucocorticoid synthesis|glucocorticoid formation|glucocorticoid biosynthesis http://purl.obolibrary.org/obo/GO_0006704 GO:0006705 biolink:BiologicalProcess mineralocorticoid biosynthetic process The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. go-plus.json mineralocorticoid anabolism|mineralocorticoid synthesis|mineralocorticoid biosynthesis|mineralocorticoid formation http://purl.obolibrary.org/obo/GO_0006705 GO:0006702 biolink:BiologicalProcess androgen biosynthetic process The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. go-plus.json androgen anabolism|androgen biosynthesis|androgen synthesis|androgen formation http://purl.obolibrary.org/obo/GO_0006702 GO:0006703 biolink:BiologicalProcess estrogen biosynthetic process The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. go-plus.json estrogen formation|oestrogen biosynthesis|oestrogen biosynthetic process|estrogen anabolism|estrogen synthesis|estrogen biosynthesis http://purl.obolibrary.org/obo/GO_0006703 GO:0006700 biolink:BiologicalProcess C21-steroid hormone biosynthetic process The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. go-plus.json C21-steroid hormone biosynthesis|C21-steroid hormone anabolism|C21-steroid hormone synthesis|C21-steroid hormone formation http://purl.obolibrary.org/obo/GO_0006700 GO:0006701 biolink:BiologicalProcess progesterone biosynthetic process The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. go-plus.json progesterone anabolism|progesterone synthesis|progesterone biosynthesis|progesterone formation http://purl.obolibrary.org/obo/GO_0006701 CHEBI:32549 biolink:ChemicalSubstance epsilon-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_32549 chebi_ph7_3 UBERON:0007778 biolink:AnatomicalEntity umbilical artery endothelium An endothelium that is part of a umbilical artery. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007778 UBERON:0007779 biolink:AnatomicalEntity transudate Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces go-plus.json plasma ultrafiltrate http://purl.obolibrary.org/obo/UBERON_0007779 CHEBI:32544 biolink:ChemicalSubstance nicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32544 chebi_ph7_3 GO:0006708 biolink:BiologicalProcess ecdysone catabolic process The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. go-plus.json ecdysone degradation|ecdysone catabolism|ecdysone breakdown http://purl.obolibrary.org/obo/GO_0006708 UBERON:0007771 biolink:AnatomicalEntity epidermis gland A gland that is part of a epidermis. go-plus.json epidermal gland|gland of epidermis http://purl.obolibrary.org/obo/UBERON_0007771 GO:0006709 biolink:BiologicalProcess progesterone catabolic process The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. go-plus.json progesterone degradation|progesterone breakdown|progesterone catabolism http://purl.obolibrary.org/obo/GO_0006709 GO:0006706 biolink:BiologicalProcess steroid catabolic process The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. go-plus.json steroid breakdown|steroid catabolism|steroid degradation http://purl.obolibrary.org/obo/GO_0006706 GO:0006707 biolink:BiologicalProcess cholesterol catabolic process The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json cholesterol degradation|cholesterol breakdown|cholesterol catabolism http://purl.obolibrary.org/obo/GO_0006707 GO:0006715 biolink:BiologicalProcess farnesol biosynthetic process The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol. go-plus.json farnesol biosynthesis|farnesol anabolism|farnesol synthesis|farnesol formation http://purl.obolibrary.org/obo/GO_0006715 GO:0006716 biolink:BiologicalProcess juvenile hormone metabolic process The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. go-plus.json juvenile hormone metabolism http://purl.obolibrary.org/obo/GO_0006716 GO:0006713 biolink:BiologicalProcess glucocorticoid catabolic process The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. go-plus.json glucocorticoid degradation|glucocorticoid catabolism|glucocorticoid breakdown http://purl.obolibrary.org/obo/GO_0006713 GO:0006714 biolink:BiologicalProcess sesquiterpenoid metabolic process The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units. go-plus.json sesquiterpenoid metabolism http://purl.obolibrary.org/obo/GO_0006714 GO:0006711 biolink:BiologicalProcess estrogen catabolic process The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. go-plus.json estrogen catabolism|oestrogen catabolic process|estrogen degradation|oestrogen catabolism|estrogen breakdown http://purl.obolibrary.org/obo/GO_0006711 GO:0006712 biolink:BiologicalProcess mineralocorticoid catabolic process The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. go-plus.json mineralocorticoid degradation|mineralocorticoid breakdown|mineralocorticoid catabolism http://purl.obolibrary.org/obo/GO_0006712 GO:0006710 biolink:BiologicalProcess androgen catabolic process The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. go-plus.json androgen degradation|androgen breakdown|androgen catabolism http://purl.obolibrary.org/obo/GO_0006710 CHEBI:32557 biolink:ChemicalSubstance D-lysinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32557 chebi_ph7_3 CHEBI:32558 biolink:ChemicalSubstance D-lysinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32558 CHEBI:32559 biolink:ChemicalSubstance D-lysyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32559 CHEBI:32550 biolink:ChemicalSubstance L-lysinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32550 CHEBI:32551 biolink:ChemicalSubstance L-lysinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32551 chebi_ph7_3 CHEBI:32552 biolink:ChemicalSubstance L-lysinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32552 CHEBI:32553 biolink:ChemicalSubstance L-lysyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32553 CHEBI:32556 biolink:ChemicalSubstance D-lysinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32556 GO:0006719 biolink:BiologicalProcess juvenile hormone catabolic process The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. go-plus.json juvenile hormone catabolism|juvenile hormone degradation|juvenile hormone breakdown http://purl.obolibrary.org/obo/GO_0006719 GO:0006717 biolink:BiologicalProcess obsolete juvenile hormone binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json juvenile hormone binding http://purl.obolibrary.org/obo/GO_0006717 GO:0006718 biolink:BiologicalProcess juvenile hormone biosynthetic process The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. go-plus.json juvenile hormone anabolism|juvenile hormone synthesis|juvenile hormone formation|juvenile hormone biosynthesis http://purl.obolibrary.org/obo/GO_0006718 CHEBI:32524 biolink:ChemicalSubstance D-histidinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32524 CHEBI:32526 biolink:ChemicalSubstance D-histidinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32526 CHEBI:32527 biolink:ChemicalSubstance D-histidinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32527 CHEBI:32529 biolink:ChemicalSubstance histidinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32529 CHEBI:32523 biolink:ChemicalSubstance D-histidinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32523 CHEBI:32535 biolink:ChemicalSubstance histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32535 CHEBI:32536 biolink:ChemicalSubstance histidinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32536 CHEBI:533015 biolink:ChemicalSubstance 3,3',5-triiodo-L-thyronine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_533015 chebi_ph7_3 CHEBI:32538 biolink:ChemicalSubstance bacillosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32538 CHEBI:32539 biolink:ChemicalSubstance daunosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32539 CHEBI:32530 biolink:ChemicalSubstance histidinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32530 CHEBI:32531 biolink:ChemicalSubstance histidinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32531 CHEBI:32532 biolink:ChemicalSubstance histidinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32532 NCBITaxon:5148 biolink:OrganismalEntity Sordariaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5148 CHEBI:32504 biolink:ChemicalSubstance phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32504 CHEBI:32505 biolink:ChemicalSubstance phenylalaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32505 CHEBI:32507 biolink:ChemicalSubstance glycinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32507 CHEBI:32508 biolink:ChemicalSubstance glycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32508 CHEBI:32513 biolink:ChemicalSubstance L-histidinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32513 CHEBI:32510 biolink:ChemicalSubstance L-histidinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32510 CHEBI:32511 biolink:ChemicalSubstance L-histidinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32511 CHEBI:32512 biolink:ChemicalSubstance L-histidinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32512 UBERON:0007798 biolink:AnatomicalEntity vascular system Anatomical system that consists of all blood and lymph vessels. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007798 UBERON:0007794 biolink:AnatomicalEntity secretion of serous gland Any fluid produced by a serous gland. go-plus.json serosal fluid|serous fluid|serous gland fluid http://purl.obolibrary.org/obo/UBERON_0007794 NCBITaxon:5139 biolink:OrganismalEntity Sordariales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5139 CHEBI:81548 biolink:ChemicalSubstance 3-vinylbacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_81548 CHEBI:81546 biolink:ChemicalSubstance bacteriochlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_81546 CHEBI:81544 biolink:ChemicalSubstance 3-(1-hydroxyethyl)bacteriochlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_81544 CHEBI:81545 biolink:ChemicalSubstance 3-(1-hydroxyethyl)chlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_81545 NCBITaxon:5141 biolink:OrganismalEntity Neurospora crassa go-plus.json Chrysonilia crassa http://purl.obolibrary.org/obo/NCBITaxon_5141 NCBITaxon:5140 biolink:OrganismalEntity Neurospora go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5140 GO:0031748 biolink:MolecularActivity D1 dopamine receptor binding Binding to a D1 dopamine receptor. go-plus.json D1 dopamine receptor ligand|D1A dopamine receptor binding http://purl.obolibrary.org/obo/GO_0031748 GO:0031749 biolink:MolecularActivity D2 dopamine receptor binding Binding to a D2 dopamine receptor. go-plus.json D2 dopamine receptor ligand http://purl.obolibrary.org/obo/GO_0031749 GO:0031746 biolink:MolecularActivity type 1 cysteinyl leukotriene receptor binding Binding to a type 1 cysteinyl leukotriene receptor. go-plus.json type 1 cysteinyl leukotriene receptor ligand http://purl.obolibrary.org/obo/GO_0031746 GO:0031747 biolink:MolecularActivity type 2 cysteinyl leukotriene receptor binding Binding to a type 2 cysteinyl leukotriene receptor. go-plus.json type 2 cysteinyl leukotriene receptor ligand http://purl.obolibrary.org/obo/GO_0031747 GO:0006788 biolink:BiologicalProcess heme oxidation The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme. go-plus.json haem oxidation http://purl.obolibrary.org/obo/GO_0006788 GO:0090040 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090040 GO:0031744 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031744 GO:0006789 biolink:BiologicalProcess bilirubin conjugation The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin. go-plus.json http://purl.obolibrary.org/obo/GO_0006789 GO:0090041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090041 GO:0031745 biolink:MolecularActivity cysteinyl leukotriene receptor binding Binding to a cysteinyl leukotriene receptor. go-plus.json cysteinyl leukotriene receptor ligand http://purl.obolibrary.org/obo/GO_0031745 GO:0006786 biolink:BiologicalProcess heme C biosynthetic process The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f. go-plus.json heme C anabolism|heme C synthesis|heme C formation|haem C biosynthetic process|haem C biosynthesis|heme C biosynthesis http://purl.obolibrary.org/obo/GO_0006786 GO:0031742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031742 GO:0006787 biolink:BiologicalProcess porphyrin-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. go-plus.json porphyrin degradation|porphyrin breakdown|porphyrin catabolism|porphyrin catabolic process http://purl.obolibrary.org/obo/GO_0006787 GO:0031743 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031743 GO:0006784 biolink:BiologicalProcess heme A biosynthetic process The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3. go-plus.json heme A anabolism|haem A biosynthesis|heme A synthesis|haem A biosynthetic process|heme A formation|heme A biosynthesis http://purl.obolibrary.org/obo/GO_0006784 GO:0006785 biolink:BiologicalProcess heme B biosynthetic process The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. go-plus.json protoheme biosynthesis|protoheme biosynthetic process|heme B anabolism|heme B synthesis|haem B biosynthesis|haem B biosynthetic process|heme B formation|heme B biosynthesis http://purl.obolibrary.org/obo/GO_0006785 GO:0006782 biolink:BiologicalProcess protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX. go-plus.json protoporphyrinogen IX anabolism|protoporphyrinogen IX synthesis|protoporphyrinogen IX biosynthesis|protoporphyrinogen IX formation http://purl.obolibrary.org/obo/GO_0006782 GO:0006783 biolink:BiologicalProcess heme biosynthetic process The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. MetaCyc:HEMESYN2-PWY go-plus.json heme anabolism|haem biosynthesis|haem biosynthetic process|heme synthesis|heme formation|heme biosynthesis http://purl.obolibrary.org/obo/GO_0006783 GO:0006780 biolink:BiologicalProcess uroporphyrinogen III biosynthetic process The chemical reactions and pathways resulting in the formation of uroporphyrinogen III. go-plus.json uroporphyrinogen III biosynthesis|uroporphyrinogen III anabolism|uroporphyrinogen III synthesis|uroporphyrinogen III formation http://purl.obolibrary.org/obo/GO_0006780 GO:0006781 biolink:BiologicalProcess succinyl-CoA pathway The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX. go-plus.json biosynthetic process of protoporphyrin IX via succinyl CoA|biosynthesis of protoporphyrin IX via succinyl CoA|biosynthetic process of protoporphyrin IX via succinyl-CoA|biosynthesis of protoporphyrin IX via succinyl-CoA|succinyl CoA pathway http://purl.obolibrary.org/obo/GO_0006781 GO:0016107 biolink:BiologicalProcess sesquiterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units. go-plus.json sesquiterpenoid catabolism|sesquiterpenoid degradation|sesquiterpenoid breakdown http://purl.obolibrary.org/obo/GO_0016107 GO:0016108 biolink:BiologicalProcess tetraterpenoid metabolic process The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units. go-plus.json tetraterpene metabolic process|tetraterpene metabolism|tetraterpenoid metabolism http://purl.obolibrary.org/obo/GO_0016108 GO:0016109 biolink:BiologicalProcess tetraterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units. go-plus.json tetraterpenoid anabolism|tetraterpene biosynthesis|tetraterpene biosynthetic process|tetraterpenoid synthesis|tetraterpenoid formation|tetraterpenoid biosynthesis http://purl.obolibrary.org/obo/GO_0016109 GO:0016103 biolink:BiologicalProcess diterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units. go-plus.json diterpenoid catabolism|diterpenoid degradation|diterpenoid breakdown|diterpene catabolism|diterpene catabolic process http://purl.obolibrary.org/obo/GO_0016103 GO:0016104 biolink:BiologicalProcess triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units. go-plus.json triterpenoid anabolism|triterpenoid synthesis|triterpenoid formation|triterpene biosynthetic process|triterpene biosynthesis|triterpenoid biosynthesis http://purl.obolibrary.org/obo/GO_0016104 GO:0016105 biolink:BiologicalProcess triterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units. go-plus.json triterpene catabolism|triterpenoid degradation|triterpenoid catabolism|triterpenoid breakdown|triterpene catabolic process http://purl.obolibrary.org/obo/GO_0016105 GO:0016106 biolink:BiologicalProcess sesquiterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units. go-plus.json sesquiterpenoid synthesis|sesquiterpenoid formation|sesquiterpenoid biosynthesis|sesquiterpenoid anabolism http://purl.obolibrary.org/obo/GO_0016106 GO:0090044 biolink:BiologicalProcess positive regulation of tubulin deacetylation Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0090044 GO:0031740 biolink:MolecularActivity type A cholecystokinin receptor binding Binding to a type A cholecystokinin receptor. go-plus.json type A cholecystokinin receptor ligand http://purl.obolibrary.org/obo/GO_0031740 GO:0016100 biolink:BiologicalProcess monoterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton. go-plus.json monoterpenoid catabolism|monoterpenoid degradation|monoterpenoid breakdown http://purl.obolibrary.org/obo/GO_0016100 GO:0090045 biolink:BiologicalProcess positive regulation of deacetylase activity Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0090045 GO:0031741 biolink:MolecularActivity type B gastrin/cholecystokinin receptor binding Binding to a type B gastrin/cholecystokinin receptor. go-plus.json type B gastrin/cholecystokinin receptor ligand http://purl.obolibrary.org/obo/GO_0031741 GO:0016101 biolink:BiologicalProcess diterpenoid metabolic process The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units. go-plus.json diterpenoid metabolism|diterpene metabolic process|diterpene metabolism http://purl.obolibrary.org/obo/GO_0016101 GO:0090042 biolink:BiologicalProcess tubulin deacetylation The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_0090042 GO:0016102 biolink:BiologicalProcess diterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units. go-plus.json diterpenoid synthesis|diterpenoid biosynthesis|diterpenoid formation|diterpene biosynthetic process|diterpene biosynthesis|diterpenoid anabolism http://purl.obolibrary.org/obo/GO_0016102 GO:0090043 biolink:BiologicalProcess regulation of tubulin deacetylation Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0090043 GO:0090048 biolink:BiologicalProcess obsolete negative regulation of transcription regulator activity OBSOLETE. Any process that decreases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. go-plus.json negative regulation of transcription regulator activity http://purl.obolibrary.org/obo/GO_0090048 GO:0090049 biolink:BiologicalProcess regulation of cell migration involved in sprouting angiogenesis Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090049 GO:0090046 biolink:BiologicalProcess obsolete regulation of transcription regulator activity OBSOLETE. Any process that modulates the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. go-plus.json regulation of transcription regulator activity http://purl.obolibrary.org/obo/GO_0090046 GO:0090047 biolink:BiologicalProcess obsolete positive regulation of transcription regulator activity OBSOLETE. Any process that increases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. go-plus.json positive regulation of transcription regulator activity http://purl.obolibrary.org/obo/GO_0090047 GO:0031737 biolink:MolecularActivity CX3C chemokine receptor binding Binding to a CX3C chemokine receptor. go-plus.json fractalkine receptor binding|CX3C chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031737 GO:0031738 biolink:MolecularActivity XCR1 chemokine receptor binding Binding to a XCR1 chemokine receptor. go-plus.json lymphotactin receptor binding|XCR1 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031738 GO:0031735 biolink:MolecularActivity CCR10 chemokine receptor binding Binding to a CCR10 chemokine receptor. go-plus.json CCR10 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031735 GO:0031736 biolink:MolecularActivity CCR11 chemokine receptor binding Binding to a CCR11 chemokine receptor. go-plus.json CCR11 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031736 GO:0090051 biolink:BiologicalProcess negative regulation of cell migration involved in sprouting angiogenesis Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090051 GO:0006799 biolink:BiologicalProcess polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid. go-plus.json polyphosphate biosynthesis|polyphosphate anabolism|polyphosphate synthesis|polyphosphate formation http://purl.obolibrary.org/obo/GO_0006799 GO:0031733 biolink:MolecularActivity CCR8 chemokine receptor binding Binding to a CCR8 chemokine receptor. go-plus.json CCR8 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031733 GO:0090052 biolink:BiologicalProcess regulation of pericentric heterochromatin assembly Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin. go-plus.json regulation of chromatin silencing at centromere http://purl.obolibrary.org/obo/GO_0090052 GO:0031734 biolink:MolecularActivity CCR9 chemokine receptor binding Binding to a CCR9 chemokine receptor. go-plus.json CCR9 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031734 GO:0031731 biolink:MolecularActivity CCR6 chemokine receptor binding Binding to a CCR6 chemokine receptor. go-plus.json LARC receptor binding|CCR6 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031731 GO:0006797 biolink:BiologicalProcess polyphosphate metabolic process The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid. go-plus.json polyphosphate metabolism http://purl.obolibrary.org/obo/GO_0006797 GO:0090050 biolink:BiologicalProcess positive regulation of cell migration involved in sprouting angiogenesis Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090050 GO:0031732 biolink:MolecularActivity CCR7 chemokine receptor binding Binding to a CCR7 chemokine receptor. go-plus.json MIP-3 beta receptor binding|type 1 EBV-induced G-protein coupled receptor binding|CCR7 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031732 GO:0006798 biolink:BiologicalProcess polyphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid. go-plus.json polyphosphate catabolism|polyphosphate degradation|polyphosphate breakdown http://purl.obolibrary.org/obo/GO_0006798 GO:0006795 biolink:BiologicalProcess regulation of phosphorus utilization Any process that modulates the frequency, rate or extent of phosphorus utilization. go-plus.json http://purl.obolibrary.org/obo/GO_0006795 GO:0006796 biolink:BiologicalProcess phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. go-plus.json phosphate metabolic process|phosphate metabolism http://purl.obolibrary.org/obo/GO_0006796 GO:0006793 biolink:BiologicalProcess phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). go-plus.json phosphorus metabolism http://purl.obolibrary.org/obo/GO_0006793 goslim_pir GO:0006794 biolink:BiologicalProcess phosphorus utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0006794 GO:0006791 biolink:BiologicalProcess sulfur utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism. go-plus.json sulphur utilization http://purl.obolibrary.org/obo/GO_0006791 GO:0006792 biolink:BiologicalProcess regulation of sulfur utilization Any process that modulates the frequency, rate or extent of sulfur utilization. go-plus.json regulation of sulphur utilization http://purl.obolibrary.org/obo/GO_0006792 GO:0031739 biolink:MolecularActivity cholecystokinin receptor binding Binding to a cholecystokinin receptor. go-plus.json cholecystokinin receptor ligand http://purl.obolibrary.org/obo/GO_0031739 GO:0006790 biolink:BiologicalProcess sulfur compound metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. Wikipedia:Sulfur_metabolism go-plus.json sulfur metabolism|sulphur metabolism|sulphur metabolic process http://purl.obolibrary.org/obo/GO_0006790 goslim_pombe|goslim_chembl|goslim_pir|goslim_drosophila|goslim_generic GO:0016118 biolink:BiologicalProcess carotenoid catabolic process The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. go-plus.json carotenoid degradation|carotenoid breakdown|carotenoid catabolism http://purl.obolibrary.org/obo/GO_0016118 GO:0016119 biolink:BiologicalProcess carotene metabolic process The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids. go-plus.json carotene metabolism http://purl.obolibrary.org/obo/GO_0016119 CHEBI:112106 biolink:ChemicalSubstance (R)-3-(indol-3-yl)-2-oxobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_112106 GO:0016114 biolink:BiologicalProcess terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. Wikipedia:Terpenoid go-plus.json terpenoid anabolism|terpenoid synthesis|terpenoid formation|terpenoid biosynthesis http://purl.obolibrary.org/obo/GO_0016114 GO:0016115 biolink:BiologicalProcess terpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. go-plus.json terpenoid catabolism|terpenoid degradation|terpenoid breakdown http://purl.obolibrary.org/obo/GO_0016115 GO:0016116 biolink:BiologicalProcess carotenoid metabolic process The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. go-plus.json carotenoid metabolism http://purl.obolibrary.org/obo/GO_0016116 GO:0016117 biolink:BiologicalProcess carotenoid biosynthetic process The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. MetaCyc:CAROTENOID-PWY go-plus.json carotenoid biosynthesis|carotenoid anabolism|carotenoid synthesis|carotenoid formation http://purl.obolibrary.org/obo/GO_0016117 GO:0016110 biolink:BiologicalProcess tetraterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units. go-plus.json tetraterpenoid catabolism|tetraterpenoid degradation|tetraterpenoid breakdown|tetraterpene catabolic process|tetraterpene catabolism http://purl.obolibrary.org/obo/GO_0016110 GO:0090055 biolink:BiologicalProcess positive regulation of silent mating-type cassette heterochromatin assembly Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. go-plus.json positive regulation of chromatin silencing at silent mating-type cassette http://purl.obolibrary.org/obo/GO_0090055 GO:0016111 biolink:BiologicalProcess polyterpenoid metabolic process The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units. go-plus.json polyterpene metabolism|polyterpene metabolic process|polyterpenoid metabolism http://purl.obolibrary.org/obo/GO_0016111 GO:0031730 biolink:MolecularActivity CCR5 chemokine receptor binding Binding to a CCR5 chemokine receptor. go-plus.json CCR5 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031730 GO:0090056 biolink:BiologicalProcess regulation of chlorophyll metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll. go-plus.json http://purl.obolibrary.org/obo/GO_0090056 GO:0016112 biolink:BiologicalProcess polyterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units. go-plus.json polyterpene biosynthetic process|polyterpene biosynthesis|polyterpenoid biosynthesis|polyterpenoid anabolism|polyterpenoid synthesis|polyterpenoid formation http://purl.obolibrary.org/obo/GO_0016112 GO:0090053 biolink:BiologicalProcess positive regulation of pericentric heterochromatin assembly Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin. go-plus.json positive regulation of chromatin silencing at centromere http://purl.obolibrary.org/obo/GO_0090053 GO:0016113 biolink:BiologicalProcess polyterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units. go-plus.json polyterpenoid degradation|polyterpenoid catabolism|polyterpenoid breakdown|polyterpene catabolic process|polyterpene catabolism http://purl.obolibrary.org/obo/GO_0016113 GO:0090054 biolink:BiologicalProcess regulation of silent mating-type cassette heterochromatin assembly Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. go-plus.json regulation of chromatin silencing at silent mating-type cassette http://purl.obolibrary.org/obo/GO_0090054 GO:0090059 biolink:BiologicalProcess protoxylem development The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem. go-plus.json http://purl.obolibrary.org/obo/GO_0090059 GO:0090057 biolink:BiologicalProcess root radial pattern formation The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis. go-plus.json http://purl.obolibrary.org/obo/GO_0090057 GO:0090058 biolink:BiologicalProcess metaxylem development The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0090058 GO:0031726 biolink:MolecularActivity CCR1 chemokine receptor binding Binding to a CCR1 chemokine receptor. go-plus.json CCR1 chemokine receptor ligand|macrophage inflammatory protein-1 alpha receptor binding http://purl.obolibrary.org/obo/GO_0031726 GO:0031727 biolink:MolecularActivity CCR2 chemokine receptor binding Binding to a CCR2 chemokine receptor. go-plus.json monocyte chemoattractant protein 1 receptor binding|CCR2 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031727 GO:0006768 biolink:BiologicalProcess biotin metabolic process The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. Wikipedia:Biotin go-plus.json vitamin H metabolism|vitamin B7 metabolic process|vitamin B7 metabolism|vitamin H metabolic process|biotin metabolism http://purl.obolibrary.org/obo/GO_0006768 GO:0031724 biolink:MolecularActivity CXCR5 chemokine receptor binding Binding to a CXCR5 chemokine receptor. go-plus.json CXCR5 chemokine receptor ligand|type 1 Burkitt's lymphoma receptor binding http://purl.obolibrary.org/obo/GO_0031724 GO:0006769 biolink:BiologicalProcess nicotinamide metabolic process The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms. MetaCyc:PWY-5083 go-plus.json niacin metabolism|niacin metabolic process|vitamin B3 metabolism|nicotinamide metabolism|vitamin B3 metabolic process http://purl.obolibrary.org/obo/GO_0006769 GO:0031725 biolink:MolecularActivity CXCR6 chemokine receptor binding Binding to a CXCR6 chemokine receptor. go-plus.json CXCR6 chemokine receptor ligand|bonzo receptor binding|STRL33 receptor binding http://purl.obolibrary.org/obo/GO_0031725 GO:0006766 biolink:BiologicalProcess vitamin metabolic process The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems. go-plus.json vitamin metabolism http://purl.obolibrary.org/obo/GO_0006766 goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus|goslim_pombe GO:0031722 biolink:MolecularActivity hemoglobin beta binding Binding to a hemoglobin beta chain. go-plus.json http://purl.obolibrary.org/obo/GO_0031722 GO:0031723 biolink:MolecularActivity CXCR4 chemokine receptor binding Binding to a CXCR4 chemokine receptor. go-plus.json CXCR4 chemokine receptor ligand|stromal cell-derived factor 1 receptor binding http://purl.obolibrary.org/obo/GO_0031723 GO:0006767 biolink:BiologicalProcess water-soluble vitamin metabolic process The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water. go-plus.json water-soluble vitamin metabolism http://purl.obolibrary.org/obo/GO_0006767 GO:0006764 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006764 GO:0031720 biolink:MolecularActivity haptoglobin binding Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031720 GO:0031721 biolink:MolecularActivity hemoglobin alpha binding Binding to a hemoglobin alpha chain. go-plus.json http://purl.obolibrary.org/obo/GO_0031721 GO:0006765 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006765 GO:0006762 biolink:BiologicalProcess obsolete dihydrofolate reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json dihydrofolate reduction http://purl.obolibrary.org/obo/GO_0006762 GO:0006763 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006763 GO:0006760 biolink:BiologicalProcess folic acid-containing compound metabolic process The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units. go-plus.json vitamin B9 and derivative metabolic process|folate-containing compound metabolism|folate and derivative metabolism|folate and derivative metabolic process|folate-containing compound metabolic process|vitamin B9 and derivative metabolism|folic acid-containing compound metabolism|folic acid and derivative metabolism|vitamin M and derivative metabolism|vitamin M and derivative metabolic process|folic acid and derivative metabolic process http://purl.obolibrary.org/obo/GO_0006760 GO:0006761 biolink:BiologicalProcess dihydrofolate biosynthetic process The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate. go-plus.json dihydrofolate biosynthesis|dihydrofolate anabolism|dihydrofolate synthesis|dihydrofolate formation|7,8-dihydrofolate biosynthesis|7,8-dihydrofolate biosynthetic process http://purl.obolibrary.org/obo/GO_0006761 GO:0031728 biolink:MolecularActivity CCR3 chemokine receptor binding Binding to a CCR3 chemokine receptor. go-plus.json eosinophil eotaxin receptor binding|CCR3 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031728 GO:0031729 biolink:MolecularActivity CCR4 chemokine receptor binding Binding to a CCR4 chemokine receptor. go-plus.json CCR4 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0031729 GO:0090028 biolink:BiologicalProcess positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0090028 GO:0090029 biolink:BiologicalProcess negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0090029 NCBITaxon:5178 biolink:OrganismalEntity Helotiales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5178 GO:0090022 biolink:BiologicalProcess regulation of neutrophil chemotaxis Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0090022 GO:0090023 biolink:BiologicalProcess positive regulation of neutrophil chemotaxis Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0090023 NCBITaxon:5179 biolink:OrganismalEntity Sclerotinia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5179 GO:0090020 biolink:BiologicalProcess obsolete regulation of transcription involved in posterior neural plate formation OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the posterior neural plate. go-plus.json http://purl.obolibrary.org/obo/GO_0090020 GO:0090021 biolink:BiologicalProcess positive regulation of posterior neural plate formation by Wnt signaling pathway The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation. go-plus.json positive regulation of posterior neural plate formation by Wnt receptor signaling pathway|positive regulation of posterior neural plate formation by Wnt receptor signalling pathway|positive regulation of posterior neural plate formation by Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_0090021 GO:0090026 biolink:BiologicalProcess positive regulation of monocyte chemotaxis Any process that increases the frequency, rate, or extent of monocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_0090026 GO:0090027 biolink:BiologicalProcess negative regulation of monocyte chemotaxis Any process that decreases the frequency, rate, or extent of monocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_0090027 GO:0090024 biolink:BiologicalProcess negative regulation of neutrophil chemotaxis Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0090024 GO:0090025 biolink:BiologicalProcess regulation of monocyte chemotaxis Any process that modulates the frequency, rate, or extent of monocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_0090025 NCBITaxon:100474 biolink:OrganismalEntity Batrachochytrium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_100474 GO:0031715 biolink:MolecularActivity C5L2 anaphylatoxin chemotactic receptor binding Binding to a C5L2 anaphylatoxin chemotactic receptor. go-plus.json C5L2 anaphylatoxin chemotactic receptor ligand http://purl.obolibrary.org/obo/GO_0031715 GO:0031716 biolink:MolecularActivity calcitonin receptor binding Binding to a calcitonin receptor. go-plus.json calcitonin receptor ligand http://purl.obolibrary.org/obo/GO_0031716 GO:0031713 biolink:MolecularActivity B2 bradykinin receptor binding Binding to a B2 bradykinin receptor. go-plus.json B2 bradykinin receptor ligand http://purl.obolibrary.org/obo/GO_0031713 GO:0006779 biolink:BiologicalProcess porphyrin-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. go-plus.json porphyrin biosynthetic process|porphyrin biosynthesis|porphyrin anabolism|porphyrin synthesis|porphyrin formation http://purl.obolibrary.org/obo/GO_0006779 GO:0031714 biolink:MolecularActivity C5a anaphylatoxin chemotactic receptor binding Binding to a C5a anaphylatoxin chemotactic receptor. go-plus.json C5a anaphylatoxin chemotactic receptor ligand http://purl.obolibrary.org/obo/GO_0031714 GO:0031711 biolink:MolecularActivity bradykinin receptor binding Binding to a bradykinin receptor. go-plus.json bradykinin receptor ligand http://purl.obolibrary.org/obo/GO_0031711 GO:0006777 biolink:BiologicalProcess Mo-molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. MetaCyc:PWY-6823 go-plus.json Mo-molybdopterin cofactor formation|Moco biosynthesis|Moco biosynthetic process|molybdenum cofactor biosynthetic process|Mo-molybdopterin cofactor biosynthesis|Mo-molybdopterin cofactor anabolism|Mo-molybdopterin cofactor synthesis http://purl.obolibrary.org/obo/GO_0006777 GO:0031712 biolink:MolecularActivity B1 bradykinin receptor binding Binding to a B1 bradykinin receptor. go-plus.json B1 bradykinin receptor ligand http://purl.obolibrary.org/obo/GO_0031712 GO:0090030 biolink:BiologicalProcess regulation of steroid hormone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0090030 GO:0006778 biolink:BiologicalProcess porphyrin-containing compound metabolic process The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. go-plus.json porphyrin metabolism|porphyrin metabolic process http://purl.obolibrary.org/obo/GO_0006778 GO:0006775 biolink:BiologicalProcess fat-soluble vitamin metabolic process The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. go-plus.json fat-soluble vitamin metabolism http://purl.obolibrary.org/obo/GO_0006775 GO:0031710 biolink:MolecularActivity neuromedin B receptor binding Binding to a neuromedin B receptor. go-plus.json neuromedin B receptor ligand http://purl.obolibrary.org/obo/GO_0031710 GO:0006776 biolink:BiologicalProcess vitamin A metabolic process The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene. go-plus.json vitamin A metabolism http://purl.obolibrary.org/obo/GO_0006776 GO:0006773 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006773 GO:0006774 biolink:BiologicalProcess obsolete vitamin B12 reduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json vitamin B12 reduction http://purl.obolibrary.org/obo/GO_0006774 GO:0006771 biolink:BiologicalProcess riboflavin metabolic process The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). Wikipedia:Riboflavin go-plus.json vitamin G metabolic process|vitamin G metabolism|vitamin B2 metabolism|riboflavin metabolism|vitamin B2 metabolic process http://purl.obolibrary.org/obo/GO_0006771 GO:0006772 biolink:BiologicalProcess thiamine metabolic process The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. Wikipedia:Thiamine go-plus.json vitamin B1 metabolic process|vitamin B1 metabolism|thiamine metabolism|thiamin metabolic process|thiamin metabolism http://purl.obolibrary.org/obo/GO_0006772 GO:0031719 biolink:MolecularActivity type 2 cannabinoid receptor binding Binding to a type 2 cannabinoid receptor. go-plus.json type 2 cannabinoid receptor ligand http://purl.obolibrary.org/obo/GO_0031719 GO:0006770 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006770 GO:0031717 biolink:MolecularActivity cannabinoid receptor binding Binding to a cannabinoid receptor. go-plus.json cannabinoid receptor ligand http://purl.obolibrary.org/obo/GO_0031717 GO:0031718 biolink:MolecularActivity type 1 cannabinoid receptor binding Binding to a type 1 cannabinoid receptor. go-plus.json type 1 cannabinoid receptor ligand http://purl.obolibrary.org/obo/GO_0031718 GO:0090039 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090039 NCBITaxon:5180 biolink:OrganismalEntity Sclerotinia sclerotiorum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5180 GO:0090033 biolink:BiologicalProcess positive regulation of filamentous growth Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0090033 GO:0090034 biolink:BiologicalProcess regulation of chaperone-mediated protein complex assembly Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. go-plus.json http://purl.obolibrary.org/obo/GO_0090034 GO:0090031 biolink:BiologicalProcess positive regulation of steroid hormone biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0090031 GO:0090032 biolink:BiologicalProcess negative regulation of steroid hormone biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0090032 GO:0090037 biolink:BiologicalProcess positive regulation of protein kinase C signaling Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. go-plus.json positive regulation of protein kinase C signaling cascade|positive regulation of protein kinase C signalling cascade http://purl.obolibrary.org/obo/GO_0090037 GO:0090038 biolink:BiologicalProcess negative regulation of protein kinase C signaling Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. go-plus.json negative regulation of protein kinase C signalling cascade|negative regulation of protein kinase C signaling cascade http://purl.obolibrary.org/obo/GO_0090038 GO:0090035 biolink:BiologicalProcess positive regulation of chaperone-mediated protein complex assembly Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. go-plus.json http://purl.obolibrary.org/obo/GO_0090035 GO:0090036 biolink:BiologicalProcess regulation of protein kinase C signaling Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. go-plus.json regulation of protein kinase C signaling cascade|regulation of protein kinase C signalling cascade http://purl.obolibrary.org/obo/GO_0090036 GO:0031704 biolink:MolecularActivity apelin receptor binding Binding to an apelin receptor. go-plus.json apelin receptor ligand|APJ receptor binding http://purl.obolibrary.org/obo/GO_0031704 GO:0090080 biolink:BiologicalProcess positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade. go-plus.json positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0090080 GO:0006748 biolink:BiologicalProcess lipoamide metabolic process The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group. go-plus.json lipoamide metabolism http://purl.obolibrary.org/obo/GO_0006748 GO:0090081 biolink:BiologicalProcess regulation of heart induction by regulation of canonical Wnt signaling pathway Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json regulation of heart induction by regulation of canonical Wnt-activated signaling pathway|regulation of heart induction by regulation of canonical Wnt receptor signaling pathway|regulation of heart induction by regulation of canonical Wnt receptor signalling pathway http://purl.obolibrary.org/obo/GO_0090081 GO:0006749 biolink:BiologicalProcess glutathione metabolic process The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. go-plus.json glutathione metabolism|oxidized glutathione reduction http://purl.obolibrary.org/obo/GO_0006749 GO:0031705 biolink:MolecularActivity bombesin receptor binding Binding to a bombesin receptor. go-plus.json bombesin receptor ligand http://purl.obolibrary.org/obo/GO_0031705 GO:0006746 biolink:BiologicalProcess FADH2 metabolic process The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide. go-plus.json FADH2 metabolism|reduced flavin adenine dinucleotide metabolic process http://purl.obolibrary.org/obo/GO_0006746 GO:0031702 biolink:MolecularActivity type 1 angiotensin receptor binding Binding to a type 1 angiotensin receptor. go-plus.json type 1 angiotensin receptor ligand|AT1 receptor binding http://purl.obolibrary.org/obo/GO_0031702 GO:0031703 biolink:MolecularActivity type 2 angiotensin receptor binding Binding to a type 2 angiotensin receptor. go-plus.json AT2 receptor binding|type 2 angiotensin receptor ligand http://purl.obolibrary.org/obo/GO_0031703 GO:0006747 biolink:BiologicalProcess FAD biosynthetic process The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide. go-plus.json oxidized flavin adenine dinucleotide biosynthesis|oxidized flavin adenine dinucleotide biosynthetic process|oxidized flavin-adenine dinucleotide biosynthesis|oxidized flavin-adenine dinucleotide biosynthetic process|FAD biosynthesis|FAD anabolism|FAD synthesis|FAD formation http://purl.obolibrary.org/obo/GO_0006747 GO:0006744 biolink:BiologicalProcess ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. MetaCyc:UBISYN-PWY go-plus.json coenzyme Q8 biosynthetic process|coenzyme Q8 biosynthesis|coenzyme Q9 biosynthetic process|coenzyme Q10 biosynthesis|ubiquinone synthesis|coenzyme Q9 biosynthesis|coenzyme Q10 biosynthetic process|ubiquinone formation|coenzyme Q biosynthetic process|coenzyme Q biosynthesis|ubiquinone biosynthesis|ubiquinone anabolism|coenzyme Q6 biosynthesis|coenzyme Q6 biosynthetic process http://purl.obolibrary.org/obo/GO_0006744 goslim_pombe GO:0090084 biolink:BiologicalProcess negative regulation of inclusion body assembly Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. go-plus.json http://purl.obolibrary.org/obo/GO_0090084 GO:0031700 biolink:MolecularActivity adrenomedullin receptor binding Binding to an adrenomedullin receptor. go-plus.json adrenomedullin receptor ligand http://purl.obolibrary.org/obo/GO_0031700 GO:0006745 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006745 GO:0090085 biolink:BiologicalProcess regulation of protein deubiquitination Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090085 GO:0031701 biolink:MolecularActivity angiotensin receptor binding Binding to an angiotensin receptor. go-plus.json angiotensin receptor ligand http://purl.obolibrary.org/obo/GO_0031701 GO:0090082 biolink:BiologicalProcess positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway|positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway|positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_0090082 GO:0006742 biolink:BiologicalProcess NADP catabolic process The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH. go-plus.json nicotinamide adenine dinucleotide phosphate catabolic process|NADP catabolism|NADP (reduced) catabolic process|reduced nicotinamide adenine dinucleotide phosphate catabolic process|reduced NADP catabolism|NADP (oxidized) catabolic process|oxidized NADP catabolic process|oxidized nicotinamide adenine dinucleotide phosphate catabolism|NADPH catabolic process|NADPH catabolism|NADP degradation|oxidized NADP catabolism|oxidized nicotinamide adenine dinucleotide phosphate catabolic process|NADP (oxidized) catabolism|NADP breakdown|reduced nicotinamide adenine dinucleotide phosphate catabolism|reduced NADP catabolic process|NADP (reduced) catabolism|nicotinamide adenine dinucleotide phosphate catabolism http://purl.obolibrary.org/obo/GO_0006742 GO:0090083 biolink:BiologicalProcess regulation of inclusion body assembly Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. go-plus.json http://purl.obolibrary.org/obo/GO_0090083 GO:0006743 biolink:BiologicalProcess ubiquinone metabolic process The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme. go-plus.json coenzyme Q metabolism|ubiquinone metabolism|coenzyme Q metabolic process http://purl.obolibrary.org/obo/GO_0006743 GO:0006740 biolink:BiologicalProcess NADPH regeneration A metabolic process that generates a pool of NADPH by the reduction of NADP+. go-plus.json reduced NADP regeneration|reduced nicotinamide adenine dinucleotide phosphate regeneration|NADP (reduced) regeneration http://purl.obolibrary.org/obo/GO_0006740 GO:0006741 biolink:BiologicalProcess NADP biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH. go-plus.json NADP synthesis|NADP formation|NADP biosynthesis|reduced NADP biosynthetic process|reduced NADP biosynthesis|oxidized nicotinamide adenine dinucleotide phosphate biosynthetic process|oxidized nicotinamide adenine dinucleotide phosphate biosynthesis|NADPH biosynthetic process|NADPH biosynthesis|oxidized NADP biosynthetic process|oxidized NADP biosynthesis|NADP (oxidized) biosynthesis|NADP (oxidized) biosynthetic process|reduced nicotinamide adenine dinucleotide phosphate biosynthesis|reduced nicotinamide adenine dinucleotide phosphate biosynthetic process|NADP (reduced) biosynthesis|NADP (reduced) biosynthetic process|nicotinamide adenine dinucleotide phosphate biosynthetic process|nicotinamide adenine dinucleotide phosphate biosynthesis|NADP anabolism http://purl.obolibrary.org/obo/GO_0006741 GO:0031708 biolink:MolecularActivity endothelin B receptor binding Binding to an endothelin B receptor. go-plus.json endothelin B receptor ligand http://purl.obolibrary.org/obo/GO_0031708 GO:0031709 biolink:MolecularActivity gastrin-releasing peptide receptor binding Binding to a gastrin-releasing peptide receptor. go-plus.json GRP receptor binding|gastrin-releasing peptide receptor ligand http://purl.obolibrary.org/obo/GO_0031709 GO:0031706 biolink:MolecularActivity subtype 3 bombesin receptor binding Binding to a subtype 3 bombesin receptor. go-plus.json subtype 3 bombesin receptor ligand http://purl.obolibrary.org/obo/GO_0031706 GO:0031707 biolink:MolecularActivity endothelin A receptor binding Binding to an endothelin A receptor. go-plus.json endothelin A receptor ligand|endothelin-1 receptor binding http://purl.obolibrary.org/obo/GO_0031707 CHEBI:32587 biolink:ChemicalSubstance 2-hydroxybenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_32587 GO:0090088 biolink:BiologicalProcess regulation of oligopeptide transport Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0090088 GO:0090089 biolink:BiologicalProcess regulation of dipeptide transport Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0090089 GO:0090086 biolink:BiologicalProcess negative regulation of protein deubiquitination Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0090086 GO:0090087 biolink:BiologicalProcess regulation of peptide transport Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0090087 GO:0090091 biolink:BiologicalProcess positive regulation of extracellular matrix disassembly Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0090091 GO:0006759 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006759 GO:0090092 biolink:BiologicalProcess regulation of transmembrane receptor protein serine/threonine kinase signaling pathway Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. go-plus.json regulation of transmembrane receptor protein serine/threonine kinase signalling pathway http://purl.obolibrary.org/obo/GO_0090092 GO:0006757 biolink:BiologicalProcess ATP generation from ADP The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP. go-plus.json ADP phosphorylation http://purl.obolibrary.org/obo/GO_0006757 GO:0090090 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json negative regulation of catenin protein nuclear translocation|negative regulation of Wnt receptor signaling pathway through beta-catenin|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of canonical Wnt receptor signalling pathway|negative regulation of catenin import into nucleus|negative regulation of canonical Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_0090090 GO:0006758 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006758 GO:0090095 biolink:BiologicalProcess regulation of metanephric cap mesenchymal cell proliferation Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. go-plus.json http://purl.obolibrary.org/obo/GO_0090095 GO:0006755 biolink:BiologicalProcess obsolete carbamoyl phosphate-ADP transphosphorylation OBSOLETE. (Was not defined before being made obsolete). go-plus.json carbamoyl phosphate-ADP transphosphorylation http://purl.obolibrary.org/obo/GO_0006755 GO:0090096 biolink:BiologicalProcess positive regulation of metanephric cap mesenchymal cell proliferation Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. go-plus.json http://purl.obolibrary.org/obo/GO_0090096 GO:0006756 biolink:BiologicalProcess AMP phosphorylation The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0006756 GO:0090093 biolink:BiologicalProcess regulation of fungal-type cell wall beta-glucan biosynthetic process Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0090093 GO:0006753 biolink:BiologicalProcess nucleoside phosphate metabolic process The chemical reactions and pathways involving any phosphorylated nucleoside. go-plus.json nucleoside phosphate metabolism http://purl.obolibrary.org/obo/GO_0006753 GO:0090094 biolink:BiologicalProcess metanephric cap mesenchymal cell proliferation involved in metanephros development The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. go-plus.json http://purl.obolibrary.org/obo/GO_0090094 GO:0006754 biolink:BiologicalProcess ATP biosynthetic process The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. go-plus.json ATP anabolism|ATP regeneration|ATP synthesis|ATP biosynthesis|ATP formation http://purl.obolibrary.org/obo/GO_0006754 GO:0006751 biolink:BiologicalProcess glutathione catabolic process The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. go-plus.json glutathione catabolism|glutathione degradation|glutathione breakdown http://purl.obolibrary.org/obo/GO_0006751 GO:0006752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006752 UBERON:0007719 biolink:AnatomicalEntity bone of reproductive organ A bone that is part of a reproductive organ. go-plus.json baculum|os penis/os clitoris http://purl.obolibrary.org/obo/UBERON_0007719 GO:0006750 biolink:BiologicalProcess glutathione biosynthetic process The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. MetaCyc:GLUTATHIONESYN-PWY go-plus.json glutathione synthesis|glutathione formation|glutathione biosynthesis|glutathione anabolism http://purl.obolibrary.org/obo/GO_0006750 UBERON:0007721 biolink:AnatomicalEntity interphalangeal joint of pes The interphalangeal articulations of the foot (articulations of the phalanges) are ginglymoid joints, and each has a plantar and two collateral ligaments. The arrangement of these ligaments is similar to that in the metatarsophalangeal articulations: the Extensor tendons supply the places of dorsal ligaments. go-plus.json interphalangeal joint of foot|toe joint|foot interphalangeal joint|interphalangeal joint of toe|hindlimb digit inter-phalangeal joint http://purl.obolibrary.org/obo/UBERON_0007721 UBERON:0007722 biolink:AnatomicalEntity interphalangeal joint of manus The interphalangeal articulations of hand are hinge-joints of the phalanges of the hand. There are two sets (except in the thumb): 'proximal interphalangeal joints' (PIP), those between the first (also called proximal) and second (intermediate) phalanges 'distal interphalangeal joints' (DIP), those between the second and third (distal) phalanges A similar group of articulations also function in the toes. go-plus.json interphalangeal joint of hand|interphalangeal joint of finger|articulationes interphalangeae manus|articulationes digitorum manus|IP joint|articulations of the digits|interphalangeal joints of hand|interphalangeal articulations of hand http://purl.obolibrary.org/obo/UBERON_0007722 GO:0090099 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090099 GO:0090097 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090097 GO:0090098 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090098 GO:0006726 biolink:BiologicalProcess eye pigment biosynthetic process The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye. go-plus.json eye pigment anabolism|eye pigment synthesis|eye pigment biosynthesis|eye pigment formation http://purl.obolibrary.org/obo/GO_0006726 GO:0006727 biolink:BiologicalProcess ommochrome biosynthetic process The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye. go-plus.json ommochrome biosynthesis|ommochrome anabolism|ommochrome synthesis|ommochrome formation http://purl.obolibrary.org/obo/GO_0006727 GO:0006724 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006724 GO:0006725 biolink:BiologicalProcess cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. go-plus.json aromatic compound metabolism|aromatic hydrocarbon metabolism|aromatic hydrocarbon metabolic process http://purl.obolibrary.org/obo/GO_0006725 goslim_pir GO:0090062 biolink:BiologicalProcess regulation of trehalose metabolic process Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0090062 GO:0006722 biolink:BiologicalProcess triterpenoid metabolic process The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units. go-plus.json triterpene metabolism|triterpene metabolic process|triterpenoid metabolism http://purl.obolibrary.org/obo/GO_0006722 GO:0090063 biolink:BiologicalProcess positive regulation of microtubule nucleation Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090063 GO:0006723 biolink:BiologicalProcess cuticle hydrocarbon biosynthetic process The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss. go-plus.json cuticle hydrocarbon biosynthesis|cuticle hydrocarbon anabolism|cuticle hydrocarbon synthesis|cuticle hydrocarbon formation http://purl.obolibrary.org/obo/GO_0006723 GO:0006720 biolink:BiologicalProcess isoprenoid metabolic process The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. go-plus.json isoprenoid metabolism|polyisoprenoid metabolic process|polyterpene metabolism|polyterpene metabolic process|polyisoprenoid metabolism http://purl.obolibrary.org/obo/GO_0006720 GO:0090060 biolink:BiologicalProcess regulation of metaxylem development Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0090060 GO:0090061 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090061 GO:0006721 biolink:BiologicalProcess terpenoid metabolic process The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. go-plus.json terpenoid metabolism http://purl.obolibrary.org/obo/GO_0006721 CHEBI:32568 biolink:ChemicalSubstance lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32568 CHEBI:32563 biolink:ChemicalSubstance lysinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32563 CHEBI:32564 biolink:ChemicalSubstance lysinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32564 chebi_ph7_3 CHEBI:32565 biolink:ChemicalSubstance lysinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32565 GO:0090066 biolink:BiologicalProcess regulation of anatomical structure size Any process that modulates the size of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/GO_0090066 GO:0090067 biolink:BiologicalProcess regulation of thalamus size Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus. go-plus.json http://purl.obolibrary.org/obo/GO_0090067 GO:0090064 biolink:BiologicalProcess activation of microtubule nucleation Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090064 GO:0090065 biolink:BiologicalProcess regulation of production of siRNA involved in RNA interference Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference. go-plus.json regulation of RNA interference, production of siRNA http://purl.obolibrary.org/obo/GO_0090065 GO:0006728 biolink:BiologicalProcess pteridine biosynthetic process The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group. go-plus.json pterin biosynthesis|pterin biosynthetic process|pteridine biosynthesis|pteridine anabolism|pteridine synthesis|pteridine formation http://purl.obolibrary.org/obo/GO_0006728 GO:0090068 biolink:BiologicalProcess positive regulation of cell cycle process Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. go-plus.json http://purl.obolibrary.org/obo/GO_0090068 GO:0006729 biolink:BiologicalProcess tetrahydrobiopterin biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. go-plus.json tetrahydrobiopterin anabolism|tetrahydrobiopterin synthesis|tetrahydrobiopterin formation|tetrahydrobiopterin biosynthesis|5,6,7,8-tetrahydrobiopterin biosynthetic process http://purl.obolibrary.org/obo/GO_0006729 GO:0090069 biolink:BiologicalProcess regulation of ribosome biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0090069 GO:0006737 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006737 GO:0006738 biolink:BiologicalProcess nicotinamide riboside catabolic process The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. go-plus.json nicotinamide riboside catabolism|nicotinamide riboside degradation|nicotinamide riboside breakdown|N-ribosylnicotinamide catabolic process http://purl.obolibrary.org/obo/GO_0006738 GO:0090070 biolink:BiologicalProcess positive regulation of ribosome biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0090070 GO:0006735 biolink:BiologicalProcess NADH regeneration A metabolic process that generates a pool of NADH by the reduction of NAD+. go-plus.json NAD (reduced) regeneration|reduced NAD regeneration|reduced nicotinamide adenine dinucleotide regeneration http://purl.obolibrary.org/obo/GO_0006735 GO:0006736 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006736 GO:0006733 biolink:BiologicalProcess obsolete oxidoreduction coenzyme metabolic process OBSOLETE. The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed. go-plus.json oxidoreduction coenzyme metabolism http://purl.obolibrary.org/obo/GO_0006733 GO:0090073 biolink:BiologicalProcess positive regulation of protein homodimerization activity Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. go-plus.json http://purl.obolibrary.org/obo/GO_0090073 GO:0006734 biolink:BiologicalProcess NADH metabolic process The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. go-plus.json NAD (reduced) metabolic process|NAD (reduced) metabolism|reduced NAD metabolism|reduced nicotinamide adenine dinucleotide metabolic process|reduced nicotinamide adenine dinucleotide metabolism|NADH metabolism|reduced NAD metabolic process http://purl.obolibrary.org/obo/GO_0006734 GO:0090074 biolink:BiologicalProcess negative regulation of protein homodimerization activity Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. go-plus.json http://purl.obolibrary.org/obo/GO_0090074 GO:0090071 biolink:BiologicalProcess negative regulation of ribosome biogenesis Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0090071 GO:0006731 biolink:BiologicalProcess obsolete coenzyme and prosthetic group metabolic process OBSOLETE. The chemical reactions and pathways involving coenzymes and prosthetic groups. go-plus.json coenzyme and prosthetic group metabolic process http://purl.obolibrary.org/obo/GO_0006731 GO:0006732 biolink:BiologicalProcess obsolete coenzyme metabolic process OBSOLETE. The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. go-plus.json group transfer coenzyme metabolic process|coenzyme and prosthetic group metabolism|coenzyme metabolism|coenzyme and prosthetic group metabolic process|group transfer coenzyme metabolism http://purl.obolibrary.org/obo/GO_0006732 GO:0090072 biolink:BiologicalProcess obsolete positive regulation of sodium ion transport via voltage-gated sodium channel activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of sodium ions via the activity of voltage-gated sodium channels. go-plus.json positive regulation of sodium ion transport via voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0090072 CHEBI:32579 biolink:ChemicalSubstance lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32579 GO:0006730 biolink:BiologicalProcess one-carbon metabolic process The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. UM-BBD_pathwayID:C1cyc go-plus.json one carbon metabolic process|one carbon metabolism|one-carbon transfer metabolic process|one-carbon metabolism|one-carbon transfer metabolism http://purl.obolibrary.org/obo/GO_0006730 goslim_pir CHEBI:32571 biolink:ChemicalSubstance perosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32571 UBERON:0007702 biolink:AnatomicalEntity tract of brain An axon tract that is part of a brain. go-plus.json brain tract|landmark tracts http://purl.obolibrary.org/obo/UBERON_0007702 UBERON:0007703 biolink:AnatomicalEntity spinothalamic tract A tract that originates from neurons in the spinal central gray and projects to various somatosensory nuclei of the thalamus. It is formed in the medulla by merger of the anterior spinothalamic tract and lateral spinothalamic tract (adapted from Braininfo.org) go-plus.json http://purl.obolibrary.org/obo/UBERON_0007703 GO:0090077 biolink:BiologicalProcess foam cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0090077 GO:0090078 biolink:BiologicalProcess smooth muscle derived foam cell differentiation The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0090078 GO:0090075 biolink:BiologicalProcess relaxation of muscle A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain. go-plus.json http://purl.obolibrary.org/obo/GO_0090075 GO:0090076 biolink:BiologicalProcess relaxation of skeletal muscle A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. go-plus.json http://purl.obolibrary.org/obo/GO_0090076 GO:0006739 biolink:BiologicalProcess NADP metabolic process The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH. go-plus.json oxidized nicotinamide adenine dinucleotide phosphate metabolic process|NADP metabolism|reduced NADP metabolism|reduced NADP metabolic process|oxidized nicotinamide adenine dinucleotide phosphate metabolism|NADPH metabolism|oxidized NADP metabolism|NADP (oxidized) metabolism|NAD phosphorylation and dephosphorylation|reduced nicotinamide adenine dinucleotide phosphate metabolism|NADP (reduced) metabolism|nicotinamide adenine dinucleotide phosphate metabolism|nicotinamide adenine dinucleotide phosphate metabolic process|NADP (reduced) metabolic process|reduced nicotinamide adenine dinucleotide phosphate metabolic process|NADP (oxidized) metabolic process|oxidized NADP metabolic process|NADPH metabolic process http://purl.obolibrary.org/obo/GO_0006739 GO:0090079 biolink:MolecularActivity translation regulator activity, nucleic acid binding Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0090079 FAO:0000038 biolink:OntologyClass macroconidium The larger of two types of asexual spores formed by some fungi; usually round or oblong. go-plus.json http://purl.obolibrary.org/obo/FAO_0000038 FAO:0000039 biolink:OntologyClass oospore An asexual spore formed by Oomycetes; formed upon fertilization of an oosphere. go-plus.json http://purl.obolibrary.org/obo/FAO_0000039 CHEBI:4116 biolink:ChemicalSubstance D-erythrulose 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4116 GO:0090206 biolink:BiologicalProcess negative regulation of cholesterol metabolic process Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0090206 GO:0090207 biolink:BiologicalProcess regulation of triglyceride metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. go-plus.json http://purl.obolibrary.org/obo/GO_0090207 GO:0090204 biolink:BiologicalProcess protein localization to nuclear pore A process in which a protein is transported to, or maintained in, a nuclear pore. go-plus.json protein localisation to nuclear pore http://purl.obolibrary.org/obo/GO_0090204 GO:0090205 biolink:BiologicalProcess positive regulation of cholesterol metabolic process Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0090205 GO:0090208 biolink:BiologicalProcess positive regulation of triglyceride metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. go-plus.json http://purl.obolibrary.org/obo/GO_0090208 GO:0090209 biolink:BiologicalProcess negative regulation of triglyceride metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. go-plus.json http://purl.obolibrary.org/obo/GO_0090209 GO:0090202 biolink:BiologicalProcess obsolete gene looping OBSOLETE. The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes. go-plus.json http://purl.obolibrary.org/obo/GO_0090202 GO:0090203 biolink:BiologicalProcess obsolete transcriptional activation by promoter-terminator looping OBSOLETE. The formation and maintenance of DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter. go-plus.json transcriptional activation by memory gene loops http://purl.obolibrary.org/obo/GO_0090203 GO:0090200 biolink:BiologicalProcess positive regulation of release of cytochrome c from mitochondria Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. go-plus.json http://purl.obolibrary.org/obo/GO_0090200 GO:0090201 biolink:BiologicalProcess negative regulation of release of cytochrome c from mitochondria Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. go-plus.json http://purl.obolibrary.org/obo/GO_0090201 FAO:0000047 biolink:OntologyClass cleistothecium A completely closed fruiting body formed by some fungi of the Ascomycota, containing asci. go-plus.json http://purl.obolibrary.org/obo/FAO_0000047 FAO:0000048 biolink:OntologyClass Hulle cell A specialized multinucleate cell that originates from a nest-like aggregation of hyphae during sexual development. Hulle cells serve as nurse cells to the developing cleistothecium. go-plus.json http://purl.obolibrary.org/obo/FAO_0000048 CHEBI:136181 biolink:ChemicalSubstance N-[(+)-12-hydroxy-7-isojasmonyl]-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136181 chebi_ph7_3 CHEBI:136182 biolink:ChemicalSubstance tuberonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136182 chebi_ph7_3 CHEBI:136180 biolink:ChemicalSubstance N-[(+)-7-isojasmonyl]-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136180 chebi_ph7_3 FAO:0000041 biolink:OntologyClass arthroconidium A cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. go-plus.json arthrospore http://purl.obolibrary.org/obo/FAO_0000041 FAO:0000042 biolink:OntologyClass blastoconidium An oblong or round asexual reproductive spore formed specifically by budding. go-plus.json blastospore|reproductive blastospore http://purl.obolibrary.org/obo/FAO_0000042 FAO:0000043 biolink:OntologyClass conidiophore A specialized hypha, often aerial, that gives rise to asexual spores known as conidia. go-plus.json http://purl.obolibrary.org/obo/FAO_0000043 FAO:0000044 biolink:OntologyClass sterigma A small hyphal branch or structure which supports a sporangium, a conidium, or a basidiospore. In species with biseriate (two-layered) sterigmata such as A. nidulans, the first layer comprises primary sterigmata (metulae) and the second layer secondary sterigmata (phialides). Some species, e.g. A. fumigatus, A. oryzae, and others, have only phialides. go-plus.json sterigmata (plural) http://purl.obolibrary.org/obo/FAO_0000044 FAO:0000045 biolink:OntologyClass phialide A specialized cell that buds from a metula on a developing conidiophore. Multiple phialides may bud from each metula. The phialides in turn divide asymmetrically to give rise to chains of conidia. go-plus.json secondary sterigma http://purl.obolibrary.org/obo/FAO_0000045 FAO:0000046 biolink:OntologyClass metula A specialized cell borne on a conidiophore that gives rise to phialides during the process of conidiation. go-plus.json metulae (plural)|primary sterigma http://purl.obolibrary.org/obo/FAO_0000046 GO:0090217 biolink:BiologicalProcess negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0090217 GO:0090218 biolink:BiologicalProcess positive regulation of lipid kinase activity Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0090218 GO:0090215 biolink:BiologicalProcess regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0090215 GO:0090216 biolink:BiologicalProcess positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0090216 CHEBI:4126 biolink:ChemicalSubstance D-fructofuranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4126 GO:0090219 biolink:BiologicalProcess negative regulation of lipid kinase activity Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0090219 GO:0090210 biolink:BiologicalProcess regulation of establishment of blood-brain barrier Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. go-plus.json regulation of establishment of BBB http://purl.obolibrary.org/obo/GO_0090210 GO:0090213 biolink:BiologicalProcess regulation of radial pattern formation Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur. go-plus.json regulation of radial pattern specification http://purl.obolibrary.org/obo/GO_0090213 GO:0090214 biolink:BiologicalProcess spongiotrophoblast layer developmental growth The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0090214 CHEBI:136179 biolink:ChemicalSubstance (+)-7-isojasmonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136179 chebi_ph7_3 GO:0090211 biolink:BiologicalProcess positive regulation of establishment of blood-brain barrier Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. go-plus.json positive regulation of establishment of BBB http://purl.obolibrary.org/obo/GO_0090211 GO:0090212 biolink:BiologicalProcess negative regulation of establishment of blood-brain barrier Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. go-plus.json negative regulation of establishment of BBB http://purl.obolibrary.org/obo/GO_0090212 FAO:0000014 biolink:OntologyClass ascus A sac-like structure containing sexual spores formed by Ascomycotina; mature asci may have little or no cytoplasm or cytoplasmic contents, and no nucleus outside of the spores. go-plus.json http://purl.obolibrary.org/obo/FAO_0000014 GO:0016290 biolink:MolecularActivity palmitoyl-CoA hydrolase activity Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate. MetaCyc:PWY-5148|RHEA:16645|EC:3.1.2.2|MetaCyc:PALMITOYL-COA-HYDROLASE-RXN go-plus.json long-chain fatty-acyl-CoA hydrolase activity|palmityl thioesterase activity|palmitoyl-CoA deacylase activity|palmitoyl thioesterase activity|palmityl-CoA deacylase activity|palmityl thioesterase I|palmitoyl coenzyme A hydrolase activity|fatty acyl thioesterase I http://purl.obolibrary.org/obo/GO_0016290 goslim_chembl GO:0016291 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016291 GO:0016292 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016292 FAO:0000017 biolink:OntologyClass sexual spore A spore formed following meiosis. In some species, prospores formed by meiosis may undergo one or more rounds of mitosis before they are fully mature. go-plus.json meiotically-derived spore http://purl.obolibrary.org/obo/FAO_0000017 FAO:0000018 biolink:OntologyClass unicellular structure A fungal structure that comprises a single cell. An individual cell is composed of a plasma membrane, contents internal to the plasma membrane, and any external protective or encapsulating structure. go-plus.json cell http://purl.obolibrary.org/obo/FAO_0000018 FAO:0000019 biolink:OntologyClass spore A spore produced by a fungus. A spore is a differentiated form of an organism produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. go-plus.json http://purl.obolibrary.org/obo/FAO_0000019 FAO:0000010 biolink:OntologyClass sporophore A multicellular anatomical structure that functions in the production of spores, which are directly borne upon or within sporogenous cells that form part of the sporophore. go-plus.json spore-bearing structure|fruitbody|fruiting body|fruit body|sporocarp|spore-producing structure http://purl.obolibrary.org/obo/FAO_0000010 FAO:0000011 biolink:OntologyClass mycelium A group or mass of discrete hyphae; the vegetative structure of many fungi. go-plus.json http://purl.obolibrary.org/obo/FAO_0000011 FAO:0000012 biolink:OntologyClass basidiocarp A large fruiting body that is composed of masses of intertwined hyphal elements and produces basidia and basidiospores. The basidiocarp is characteristic of the majority of fungi of the subphylum Basidiomycotina, in which it is the site of karyogamy and meiosis. Mushrooms and toadstools are common examples. go-plus.json mushroom http://purl.obolibrary.org/obo/FAO_0000012 GO:0016286 biolink:MolecularActivity small conductance calcium-activated potassium channel activity Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. go-plus.json SK KCa channels|SK calcium-activated potassium channel activity|small conductance KCa channels http://purl.obolibrary.org/obo/GO_0016286 CHEBI:136141 biolink:ChemicalSubstance lysophosphatidylethanolamine 22:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136141 GO:0016287 biolink:MolecularActivity glycerone-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA. MetaCyc:2.3.1.42-RXN|Reactome:R-HSA-75879|Reactome:R-HSA-1483002|EC:2.3.1.42|KEGG_REACTION:R01013|RHEA:17657 go-plus.json acyl-CoA:glycerone-phosphate O-acyltransferase activity|dihydroxyacetone phosphate acyltransferase activity http://purl.obolibrary.org/obo/GO_0016287 CHEBI:136142 biolink:ChemicalSubstance lysophosphatidylethanolamine O-18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136142 GO:0016288 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016288 GO:0016289 biolink:MolecularActivity CoA hydrolase activity Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group. Reactome:R-HSA-193385 go-plus.json http://purl.obolibrary.org/obo/GO_0016289 GO:0016282 biolink:CellularComponent eukaryotic 43S preinitiation complex A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA. go-plus.json eukaryotic 43S pre-initiation complex http://purl.obolibrary.org/obo/GO_0016282 GO:0016283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016283 GO:0016284 biolink:MolecularActivity obsolete alanine aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide. EC:3.4.11.- go-plus.json alanine aminopeptidase activity http://purl.obolibrary.org/obo/GO_0016284 GO:0016285 biolink:MolecularActivity obsolete cytosol alanyl aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides. MetaCyc:3.4.11.14-RXN|EC:3.4.11.14 go-plus.json puromycin-sensitive aminopeptidase activity|aminopolypeptidase activity|human liver aminopeptidase|arylamidase activity|cytosol aminopeptidase III activity|cytosol alanyl aminopeptidase activity|thiol-activated aminopeptidase activity|soluble alanyl aminopeptidase activity|liver aminopeptidase activity http://purl.obolibrary.org/obo/GO_0016285 FAO:0000026 biolink:OntologyClass urediniospore A thin-walled spore that is formed in a uredinium and is the primary dispersal mode for rust-causing Basidiomycete fungi. go-plus.json uredospore|urediospore http://purl.obolibrary.org/obo/FAO_0000026 FAO:0000021 biolink:OntologyClass basidiospore A thick-walled spore formed externally on extrusions of a basidium following sexual reproduction; found in Basidiomycetes. go-plus.json http://purl.obolibrary.org/obo/FAO_0000021 FAO:0000022 biolink:OntologyClass teliospore A diploid spore with a thick, pigmented, sculpted cell wall, and extracellular peptidoglycan spikes that is formed during growth in a plant host by some Basidiomycete species, including pathogenic smut (Ustilaginales) and rust (Pucciniales) fungi. go-plus.json http://purl.obolibrary.org/obo/FAO_0000022 FAO:0000023 biolink:OntologyClass asexual spore A spore formed following one or more rounds of mitosis, without meiosis. go-plus.json mitotically-derived spore http://purl.obolibrary.org/obo/FAO_0000023 FAO:0000024 biolink:OntologyClass conidium An asexual, nonmotile spore formed by higher fungi. Conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/FAO_0000024 GO:0016297 biolink:MolecularActivity acyl-[acyl-carrier-protein] hydrolase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid. EC:3.1.2.14|RHEA:30131|Reactome:R-HSA-5655955|MetaCyc:RXN-7902 go-plus.json S-acyl fatty acid synthase thioesterase activity|acyl-ACP thioesterase activity|acyl-acyl carrier protein hydrolase activity|acyl-ACP-hydrolase activity|acyl-acyl-carrier-protein hydrolase activity|acyl-ACP hydrolase activity|acyl-[acyl-carrier protein] hydrolase activity http://purl.obolibrary.org/obo/GO_0016297 GO:0016298 biolink:MolecularActivity lipase activity Catalysis of the hydrolysis of a lipid or phospholipid. Reactome:R-HSA-163432|Reactome:R-HSA-163402|EC:3.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016298 goslim_chembl|goslim_drosophila|goslim_aspergillus GO:0016299 biolink:MolecularActivity obsolete regulator of G-protein signaling activity OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form. go-plus.json regulator of G protein signaling activity|regulator of G protein signalling activity|regulator of G-protein signalling activity|regulator of G-protein signaling activity|RGS http://purl.obolibrary.org/obo/GO_0016299 GO:0016293 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016293 GO:0016294 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016294 GO:0016295 biolink:MolecularActivity myristoyl-[acyl-carrier-protein] hydrolase activity Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate. EC:3.1.2.14|RHEA:30123|KEGG_REACTION:R08159|MetaCyc:RXN-10727 go-plus.json tetradecanoyl-ACP hydrolase activity|myristoyl-[acyl-carrier protein] hydrolase activity|tetradecanoyl-[acyl-carrier-protein] hydrolase activity|myristoyl-ACP hydrolase activity http://purl.obolibrary.org/obo/GO_0016295 GO:0016296 biolink:MolecularActivity palmitoyl-[acyl-carrier-protein] hydrolase activity Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate. RHEA:41932|EC:3.1.2.14|KEGG_REACTION:R08162|MetaCyc:RXN-9549 go-plus.json palmitoyl-ACP hydrolase activity|palmitoyl-[acyl-carrier protein] hydrolase activity http://purl.obolibrary.org/obo/GO_0016296 NCBITaxon:43816 biolink:OrganismalEntity Anophelinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_43816 GO:0016270 biolink:BiologicalProcess O-glycan processing, core 4 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0016270 GO:0090248 biolink:BiologicalProcess cell migration involved in somitogenic axis elongation Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation. go-plus.json cell motility involved in somitogenic axis elongation http://purl.obolibrary.org/obo/GO_0090248 GO:0090249 biolink:BiologicalProcess regulation of cell migration involved in somitogenic axis elongation Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation. go-plus.json regulation of cell motility involved in somitogenic axis elongation http://purl.obolibrary.org/obo/GO_0090249 GO:0016268 biolink:BiologicalProcess O-glycan processing, core 2 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0016268 GO:0016269 biolink:BiologicalProcess O-glycan processing, core 3 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0016269 GO:0090242 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in somitogenesis The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis. go-plus.json retinoic acid receptor signalling pathway involved in somitogenesis http://purl.obolibrary.org/obo/GO_0090242 GO:0016264 biolink:BiologicalProcess gap junction assembly Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0016264 GO:0016265 biolink:BiologicalProcess obsolete death OBSOLETE. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. Wikipedia:Death go-plus.json http://purl.obolibrary.org/obo/GO_0016265 GO:0090243 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in somitogenesis The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis. go-plus.json fibroblast growth factor receptor signalling pathway involved in somitogenesis http://purl.obolibrary.org/obo/GO_0090243 CHEBI:4153 biolink:ChemicalSubstance D-galactopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4153 GO:0090240 biolink:BiologicalProcess positive regulation of histone H4 acetylation Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0090240 GO:0016266 biolink:BiologicalProcess O-glycan processing The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure. go-plus.json http://purl.obolibrary.org/obo/GO_0016266 GO:0090241 biolink:BiologicalProcess negative regulation of histone H4 acetylation Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0090241 GO:0016267 biolink:BiologicalProcess O-glycan processing, core 1 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0016267 GO:0090246 biolink:BiologicalProcess convergent extension involved in somitogenesis The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090246 GO:0016260 biolink:BiologicalProcess selenocysteine biosynthetic process The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins. go-plus.json selenocysteine anabolism|selenocysteine synthesis|selenocysteine formation|selenocysteine biosynthesis http://purl.obolibrary.org/obo/GO_0016260 GO:0090247 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090247 GO:0016261 biolink:BiologicalProcess selenocysteine catabolic process The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins. go-plus.json selenocysteine degradation|selenocysteine breakdown|selenocysteine catabolism http://purl.obolibrary.org/obo/GO_0016261 GO:0016262 biolink:MolecularActivity protein N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. EC:2.4.1.94|RHEA:16533|MetaCyc:2.4.1.94-RXN go-plus.json UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity|N-GlcNAc transferase activity|uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0016262 GO:0090244 biolink:BiologicalProcess Wnt signaling pathway involved in somitogenesis The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis. go-plus.json Wnt-activated signaling pathway involved in somitogenesis|Wnt receptor signalling|Wnt receptor signaling pathway involved in somitogenesis http://purl.obolibrary.org/obo/GO_0090244 GO:0016263 biolink:MolecularActivity glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan. RHEA:15621|Reactome:R-HSA-1964505|MetaCyc:2.4.1.122-RXN|EC:2.4.1.122|Reactome:R-HSA-6785524 go-plus.json UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity|Core 1 GalT http://purl.obolibrary.org/obo/GO_0016263 GO:0090245 biolink:BiologicalProcess axis elongation involved in somitogenesis The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090245 FAO:0000003 biolink:OntologyClass basidium A spore-producing structure found in a Basidiomycete; formed when the terminal cell of a dikaryotic hyphal branch inflates and undergoes karyogamy and meiosis. go-plus.json http://purl.obolibrary.org/obo/FAO_0000003 GO:0016280 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016280 GO:0016281 biolink:CellularComponent eukaryotic translation initiation factor 4F complex The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome. go-plus.json eIF-4F|eukaryotic translation initiation factor 4 complex http://purl.obolibrary.org/obo/GO_0016281 CHEBI:4170 biolink:ChemicalSubstance D-glucopyranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4170 FAO:0000007 biolink:OntologyClass fruitbody Any specialized structure which bears or contains sexually or asexually derived spores. go-plus.json fruiting body http://purl.obolibrary.org/obo/FAO_0000007 GO:0031898 biolink:CellularComponent chromoplast envelope The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0031898 GO:0090250 biolink:BiologicalProcess cell-cell adhesion involved in establishment of planar polarity The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0090250 GO:0031899 biolink:CellularComponent chromoplast inner membrane The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma. go-plus.json http://purl.obolibrary.org/obo/GO_0031899 FAO:0000008 biolink:OntologyClass ascocarp A structure within, or at the surface of, which an ascus develops in Ascomycetes. go-plus.json http://purl.obolibrary.org/obo/FAO_0000008 GO:0031896 biolink:MolecularActivity V2 vasopressin receptor binding Binding to a V2 vasopressin receptor. go-plus.json V2 vasopressin receptor ligand http://purl.obolibrary.org/obo/GO_0031896 GO:0031897 biolink:CellularComponent Tic complex The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane. go-plus.json chloroplast inner membrane translocase complex http://purl.obolibrary.org/obo/GO_0031897 FAO:0000001 biolink:OntologyClass fungal structure An anatomical structure that forms all or part of a fungus. go-plus.json fungal structure ontology http://purl.obolibrary.org/obo/FAO_0000001 GO:0090259 biolink:BiologicalProcess regulation of retinal ganglion cell axon guidance Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. go-plus.json http://purl.obolibrary.org/obo/GO_0090259 GO:0016279 biolink:MolecularActivity protein-lysine N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate. Reactome:R-HSA-8865237|Reactome:R-HSA-8932276|Reactome:R-HSA-8931858|Reactome:R-HSA-8932413|Reactome:R-HSA-8932221|Reactome:R-HSA-212263|Reactome:R-HSA-8932243|Reactome:R-HSA-8932275|Reactome:R-HSA-8931974 go-plus.json http://purl.obolibrary.org/obo/GO_0016279 GO:0031894 biolink:MolecularActivity V1A vasopressin receptor binding Binding to a V1A vasopressin receptor. go-plus.json V1A vasopressin receptor ligand http://purl.obolibrary.org/obo/GO_0031894 GO:0090253 biolink:BiologicalProcess convergent extension involved in imaginal disc-derived wing morphogenesis The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090253 GO:0016275 biolink:MolecularActivity [cytochrome c]-arginine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine. RHEA:21872|MetaCyc:2.1.1.124-RXN|EC:2.1.1.124 go-plus.json S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea|cytochrome c-arginine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea http://purl.obolibrary.org/obo/GO_0016275 GO:0016276 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016276 GO:0031895 biolink:MolecularActivity V1B vasopressin receptor binding Binding to a V1B vasopressin receptor. go-plus.json V1B vasopressin receptor ligand http://purl.obolibrary.org/obo/GO_0031895 GO:0090254 biolink:BiologicalProcess cell elongation involved in imaginal disc-derived wing morphogenesis The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090254 GO:0090251 biolink:BiologicalProcess protein localization involved in establishment of planar polarity Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity. go-plus.json protein localisation involved in establishment of planar polarity http://purl.obolibrary.org/obo/GO_0090251 GO:0016277 biolink:MolecularActivity [myelin basic protein]-arginine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine. go-plus.json myelin basic protein methylase activity|protein methylase I activity|myelin basic protein methylase I|S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity|myelin basic protein-arginine N-methyltransferase activity|S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0016277 GO:0031892 biolink:MolecularActivity type 2 vasoactive intestinal polypeptide receptor binding Binding to a type 2 vasoactive intestinal polypeptide receptor. go-plus.json type 3 PACAP receptor binding|type 2 vasoactive intestinal polypeptide receptor ligand http://purl.obolibrary.org/obo/GO_0031892 GO:0090252 biolink:BiologicalProcess epithelium migration involved in imaginal disc-derived wing morphogenesis The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090252 GO:0016278 biolink:MolecularActivity lysine N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue. Reactome:R-HSA-3222237|Reactome:R-HSA-6805755|Reactome:R-HSA-6805730|Reactome:R-HSA-6805740 go-plus.json http://purl.obolibrary.org/obo/GO_0016278 GO:0031893 biolink:MolecularActivity vasopressin receptor binding Binding to a vasopressin receptor. go-plus.json vasopressin receptor ligand http://purl.obolibrary.org/obo/GO_0031893 GO:0031890 biolink:MolecularActivity vasoactive intestinal polypeptide receptor binding Binding to a vasoactive intestinal polypeptide receptor. go-plus.json vasoactive intestinal polypeptide receptor ligand|VIP receptor binding http://purl.obolibrary.org/obo/GO_0031890 CHEBI:4167 biolink:ChemicalSubstance D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_4167 chebi_ph7_3 GO:0090257 biolink:BiologicalProcess regulation of muscle system process Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. go-plus.json http://purl.obolibrary.org/obo/GO_0090257 GO:0016271 biolink:BiologicalProcess obsolete tissue death OBSOLETE. A permanent cessation of all vital functions of a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0016271 GO:0031891 biolink:MolecularActivity type 1 vasoactive intestinal polypeptide receptor binding Binding to a type 1 vasoactive intestinal polypeptide receptor. go-plus.json type 2 PACAP receptor binding|type 1 vasoactive intestinal polypeptide receptor ligand http://purl.obolibrary.org/obo/GO_0031891 GO:0016272 biolink:CellularComponent prefoldin complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. Wikipedia:Prefoldin go-plus.json GIM complex http://purl.obolibrary.org/obo/GO_0016272 GO:0090258 biolink:BiologicalProcess negative regulation of mitochondrial fission Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. go-plus.json negative regulation of mitochondrial division http://purl.obolibrary.org/obo/GO_0090258 GO:0016273 biolink:MolecularActivity arginine N-methyltransferase activity Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0016273 GO:0090255 biolink:BiologicalProcess cell proliferation involved in imaginal disc-derived wing morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090255 GO:0090256 biolink:BiologicalProcess regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0090256 GO:0016274 biolink:MolecularActivity protein-arginine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine. Reactome:R-HSA-5205822|Reactome:R-HSA-5205824|Reactome:R-HSA-8879123|Reactome:R-HSA-191790|Reactome:R-HSA-5229203|Reactome:R-HSA-8934735|Reactome:R-HSA-5205820|Reactome:R-HSA-5205867|Reactome:R-HSA-5218952|Reactome:R-HSA-5229010|Reactome:R-HSA-5661126|Reactome:R-HSA-5205798 go-plus.json PRMT activity http://purl.obolibrary.org/obo/GO_0016274 GO:0031889 biolink:MolecularActivity urotensin receptor binding Binding to a urotensin receptor. go-plus.json urotensin receptor ligand http://purl.obolibrary.org/obo/GO_0031889 GO:0031887 biolink:BiologicalProcess lipid droplet transport along microtubule The directed movement of a lipid droplet along a microtubule, mediated by motor proteins. go-plus.json adiposome transport along microtubule|lipid particle transport along microtubule|lipid body transport along microtubule http://purl.obolibrary.org/obo/GO_0031887 GO:0031888 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031888 GO:0031885 biolink:MolecularActivity type 1 member 2 taste receptor binding Binding to a type 1 member 2 taste receptor. go-plus.json type 1 member 2 taste receptor ligand http://purl.obolibrary.org/obo/GO_0031885 GO:0031886 biolink:MolecularActivity type 1 member 3 taste receptor binding Binding to a type 1 member 3 taste receptor. go-plus.json sweet taste receptor binding|type 1 member 3 taste receptor ligand http://purl.obolibrary.org/obo/GO_0031886 GO:0090228 biolink:BiologicalProcess positive regulation of red or far-red light signaling pathway Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. go-plus.json positive regulation of red or far-red light signalling pathway|positive regulation of phytochrome signaling pathway http://purl.obolibrary.org/obo/GO_0090228 CHEBI:136105 biolink:ChemicalSubstance (R)-PGA2-S-glutathione conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136105 CHEBI:4139 biolink:ChemicalSubstance D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_4139 chebi_ph7_3 GO:0090229 biolink:BiologicalProcess negative regulation of red or far-red light signaling pathway Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. go-plus.json negative regulation of red or far-red light signalling pathway|negative regulation of phytochrome signaling pathway http://purl.obolibrary.org/obo/GO_0090229 CHEBI:136106 biolink:ChemicalSubstance (S)-PGA2-S-glutathione conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136106 GO:0090226 biolink:BiologicalProcess regulation of microtubule nucleation by Ran protein signal transduction Any series of molecular signals in which a Ran GTPase relays one or more of the signals resulting in the modulation of the rate, frequency or extent of microtubule nucleation. go-plus.json http://purl.obolibrary.org/obo/GO_0090226 GO:0090227 biolink:BiologicalProcess regulation of red or far-red light signaling pathway Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. go-plus.json regulation of red or far-red light signalling pathway|regulation of phytochrome signaling pathway http://purl.obolibrary.org/obo/GO_0090227 GO:0016246 biolink:BiologicalProcess RNA interference The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. Wikipedia:RNA_interference go-plus.json posttranscriptional gene silencing by siRNA|RNAi http://purl.obolibrary.org/obo/GO_0016246 GO:0016247 biolink:MolecularActivity channel regulator activity Bonds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. go-plus.json http://purl.obolibrary.org/obo/GO_0016247 CHEBI:136107 biolink:ChemicalSubstance 8,9-epoxy-(5Z,11Z,14Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136107 chebi_ph7_3 GO:0016248 biolink:MolecularActivity channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a channel. go-plus.json http://purl.obolibrary.org/obo/GO_0016248 GO:0016249 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016249 GO:0016242 biolink:BiologicalProcess negative regulation of macroautophagy Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. go-plus.json inhibition of macroautophagy|negative regulation of starvation-induced autophagy|down-regulation of macroautophagy|downregulation of macroautophagy|down regulation of macroautophagy http://purl.obolibrary.org/obo/GO_0016242 GO:0031883 biolink:MolecularActivity taste receptor binding Binding to a taste receptor. go-plus.json taste receptor ligand http://purl.obolibrary.org/obo/GO_0031883 GO:0090220 biolink:BiologicalProcess chromosome localization to nuclear envelope involved in homologous chromosome segregation The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis. go-plus.json chromosome localisation to nuclear envelope involved in homologous chromosome segregation http://purl.obolibrary.org/obo/GO_0090220 GO:0016243 biolink:BiologicalProcess regulation of autophagosome size Any process that modulates the size of the autophagosome. go-plus.json regulation of autophagic vacuole size http://purl.obolibrary.org/obo/GO_0016243 GO:0031884 biolink:MolecularActivity type 1 member 1 taste receptor binding Binding to a type 1 member 1 taste receptor. go-plus.json type 1 member 1 taste receptor ligand http://purl.obolibrary.org/obo/GO_0031884 GO:0090221 biolink:BiologicalProcess mitotic spindle-templated microtubule nucleation The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0090221 GO:0031881 biolink:MolecularActivity type 4 somatostatin receptor binding Binding to a type 4 somatostatin receptor. go-plus.json type 4 somatostatin receptor ligand http://purl.obolibrary.org/obo/GO_0031881 GO:0016244 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016244 GO:0031882 biolink:MolecularActivity type 5 somatostatin receptor binding Binding to a type 5 somatostatin receptor. go-plus.json type 5 somatostatin receptor ligand http://purl.obolibrary.org/obo/GO_0031882 GO:0016245 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016245 GO:0090224 biolink:BiologicalProcess regulation of spindle organization Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle. go-plus.json regulation of spindle organisation http://purl.obolibrary.org/obo/GO_0090224 GO:0031880 biolink:MolecularActivity type 3 somatostatin receptor binding Binding to a type 3 somatostatin receptor. go-plus.json type 3 somatostatin receptor ligand http://purl.obolibrary.org/obo/GO_0031880 GO:0090225 biolink:BiologicalProcess regulation of spindle density Any process that modulates the number of microtubules in a given region of the spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0090225 GO:0090222 biolink:BiologicalProcess centrosome-templated microtubule nucleation The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0090222 GO:0016240 biolink:BiologicalProcess autophagosome membrane docking The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere. go-plus.json autophagic vacuole docking http://purl.obolibrary.org/obo/GO_0016240 GO:0090223 biolink:BiologicalProcess chromatin-templated microtubule nucleation The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0090223 GO:0016241 biolink:BiologicalProcess regulation of macroautophagy Any process that modulates the frequency, rate or extent of macroautophagy. go-plus.json regulation of starvation-induced autophagy http://purl.obolibrary.org/obo/GO_0016241 GO:0031878 biolink:MolecularActivity type 1 somatostatin receptor binding Binding to a type 1 somatostatin receptor. go-plus.json type 1 somatostatin receptor ligand http://purl.obolibrary.org/obo/GO_0031878 GO:0031879 biolink:MolecularActivity type 2 somatostatin receptor binding Binding to a type 2 somatostatin receptor. go-plus.json type 2 somatostatin receptor ligand http://purl.obolibrary.org/obo/GO_0031879 GO:0031876 biolink:MolecularActivity secretin receptor binding Binding to a secretin receptor. go-plus.json secretin receptor ligand http://purl.obolibrary.org/obo/GO_0031876 GO:0031877 biolink:MolecularActivity somatostatin receptor binding Binding to a somatostatin receptor. go-plus.json somatostatin receptor ligand http://purl.obolibrary.org/obo/GO_0031877 GO:0031874 biolink:MolecularActivity type 3 proteinase activated receptor binding Binding to a type 3 proteinase activated receptor. go-plus.json type 3 proteinase activated receptor ligand http://purl.obolibrary.org/obo/GO_0031874 GO:0031875 biolink:MolecularActivity type 4 proteinase activated receptor binding Binding to a type 4 proteinase activated receptor. go-plus.json type 4 proteinase activated receptor ligand http://purl.obolibrary.org/obo/GO_0031875 GO:0090239 biolink:BiologicalProcess regulation of histone H4 acetylation Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0090239 CHEBI:136117 biolink:ChemicalSubstance 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136117 chebi_ph7_3 GO:0090237 biolink:BiologicalProcess regulation of arachidonic acid secretion Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0090237 GO:0090238 biolink:BiologicalProcess positive regulation of arachidonic acid secretion Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0090238 CHEBI:136115 biolink:ChemicalSubstance 11,12-epoxy-(5Z,8Z,14Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136115 chebi_ph7_3 GO:0016257 biolink:BiologicalProcess N-glycan processing to secreted and cell-surface N-glycans The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus. go-plus.json http://purl.obolibrary.org/obo/GO_0016257 GO:0016258 biolink:BiologicalProcess N-glycan diversification The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases. go-plus.json http://purl.obolibrary.org/obo/GO_0016258 GO:0016259 biolink:BiologicalProcess selenocysteine metabolic process The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins. go-plus.json selenocysteine metabolism http://purl.obolibrary.org/obo/GO_0016259 CHEBI:136118 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,15E,17S)-17-hydroperoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136118 GO:0031872 biolink:MolecularActivity type 1 proteinase activated receptor binding Binding to a type 1 proteinase activated receptor. go-plus.json thrombin receptor binding|type 1 proteinase activated receptor ligand http://purl.obolibrary.org/obo/GO_0031872 CHEBI:4141 biolink:ChemicalSubstance D-galactopyranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4141 GO:0090231 biolink:BiologicalProcess regulation of spindle checkpoint Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0090231 gocheck_do_not_manually_annotate GO:0016253 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016253 GO:0090232 biolink:BiologicalProcess positive regulation of spindle checkpoint Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. go-plus.json spindle checkpoint activation http://purl.obolibrary.org/obo/GO_0090232 gocheck_do_not_manually_annotate GO:0016254 biolink:BiologicalProcess preassembly of GPI anchor in ER membrane The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane. go-plus.json preassembly of GPI anchor in endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0016254 GO:0031873 biolink:MolecularActivity type 2 proteinase activated receptor binding Binding to a type 2 proteinase activated receptor. go-plus.json type 2 proteinase activated receptor ligand http://purl.obolibrary.org/obo/GO_0031873 GO:0031870 biolink:MolecularActivity thromboxane A2 receptor binding Binding to a thromboxane A2 receptor. go-plus.json prostanoid TP receptor binding|thromboxane A2 receptor ligand http://purl.obolibrary.org/obo/GO_0031870 GO:0016255 biolink:BiologicalProcess attachment of GPI anchor to protein A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain. go-plus.json http://purl.obolibrary.org/obo/GO_0016255 GO:0031871 biolink:MolecularActivity proteinase activated receptor binding Binding to a proteinase activated receptor. go-plus.json proteinase activated receptor ligand http://purl.obolibrary.org/obo/GO_0031871 GO:0090230 biolink:BiologicalProcess regulation of centromere complex assembly Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. go-plus.json centromere licensing http://purl.obolibrary.org/obo/GO_0090230 GO:0016256 biolink:BiologicalProcess N-glycan processing to lysosome The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0016256 GO:0090235 biolink:BiologicalProcess regulation of metaphase plate congression Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle. go-plus.json regulation of chromosome congression http://purl.obolibrary.org/obo/GO_0090235 CHEBI:136112 biolink:ChemicalSubstance (S)-PGJ2-S-glutathione conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136112 GO:0016250 biolink:MolecularActivity N-sulfoglucosamine sulfohydrolase activity Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate. MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN|Reactome:R-HSA-2090043|Reactome:R-HSA-2263444|Reactome:R-HSA-1678708|RHEA:17881|EC:3.10.1.1|Reactome:R-HSA-9036050 go-plus.json N-sulfo-D-glucosamine sulfohydrolase activity|sulphamidase activity|N-sulphoglucosamine sulphohydrolase activity|heparin sulfamidase activity|sulfoglucosamine sulfamidase activity|2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase) http://purl.obolibrary.org/obo/GO_0016250 GO:0090236 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in somitogenesis OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0090236 CHEBI:136113 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,15E,17S,19Z)-17-hydroperoxydocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136113 GO:0016251 biolink:MolecularActivity RNA polymerase II general transcription initiation factor activity A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP). In most species, RNA polymerase II transcribes all messenger RNAs (mRNAs), most untranslated regulatory RNAs, the majority of the snoRNAs, four of the five snRNAs (U1, U2, U4, and U5), and other small noncoding RNAs. For some small RNAs there is variability between species as to whether it is transcribed by RNA polymerase II or RNA polymerase III. However there are also rare exceptions, such as Trypanosoma brucei, where RNA polymerase I transcribes certain mRNAs in addition to its normal role in rRNA transcription. go-plus.json RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|general RNA polymerase II transcription factor activity|GTF2 activity|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|basal RNA polymerase II transcription factor activity|sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0016251 CHEBI:136110 biolink:ChemicalSubstance (R)-PGJ2-S-glutathione conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136110 GO:0090233 biolink:BiologicalProcess negative regulation of spindle checkpoint Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. go-plus.json spindle checkpoint silencing http://purl.obolibrary.org/obo/GO_0090233 gocheck_do_not_manually_annotate GO:0090234 biolink:BiologicalProcess regulation of kinetochore assembly Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. go-plus.json regulation of chromosome-kinetochore attachment http://purl.obolibrary.org/obo/GO_0090234 GO:0016252 biolink:MolecularActivity obsolete nonspecific RNA polymerase II transcription factor activity OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set. go-plus.json nonspecific RNA polymerase II transcription factor activity http://purl.obolibrary.org/obo/GO_0016252 NCBITaxon:28221 biolink:OrganismalEntity Deltaproteobacteria go-plus.json delta subgroup|Myxococcia|delta subdivision|Deltabacteria Cavalier-Smith 2002|Purple bacteria, delta subdivision|"Deltabacteria" Cavalier-Smith 1992|d-proteobacteria|delta proteobacteria|Proteobacteria delta subdivision http://purl.obolibrary.org/obo/NCBITaxon_28221 OBO:uberon/core#filtered_through biolink:OntologyClass filtered through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. filtered_through go-plus.json http://purl.obolibrary.org/obo/uberon/core#filtered_through CHEBI:4194 biolink:ChemicalSubstance D-hexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_4194 chebi_ph7_3 CHEBI:4195 biolink:ChemicalSubstance D-hexose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4195 UBERON:0017163 biolink:AnatomicalEntity skin bony tubercle A bony structure embedded in skin, roughly equivalent to osteoderms. go-plus.json bony tubercle|bony tubercles http://purl.obolibrary.org/obo/UBERON_0017163 NCBITaxon:43845 biolink:OrganismalEntity Drosophilinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_43845 NCBITaxon:28211 biolink:OrganismalEntity Alphaproteobacteria go-plus.json Alphabacteria|a-proteobacteria|Proteobacteria alpha subdivision|alpha subdivision|alpha proteobacteria|alpha subgroup|Purple bacteria, alpha subdivision http://purl.obolibrary.org/obo/NCBITaxon_28211 NCBITaxon:28216 biolink:OrganismalEntity Betaproteobacteria go-plus.json Proteobacteria beta subdivision|beta proteobacteria|b-proteobacteria|beta subgroup|Purple bacteria, beta subdivision|beta subdivision http://purl.obolibrary.org/obo/NCBITaxon_28216 CHEBI:4178 biolink:ChemicalSubstance D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4178 CHEBI:4177 biolink:ChemicalSubstance D-glucosylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_4177 PATO:0001408 biolink:OntologyClass ciliatedness A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body. go-plus.json http://purl.obolibrary.org/obo/PATO_0001408 SO:0100021 biolink:SequenceFeature polypeptide_conserved_region A subsection of sequence with biological interest that is conserved in different proteins. They may or may not have functional or structural significance within the proteins in which they are found. go-plus.json polypeptide conserved region http://purl.obolibrary.org/obo/SO_0100021 biosapiens CHEBI:81467 biolink:ChemicalSubstance 7alpha-hydroxypregnenolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_81467 chebi_ph7_3 PATO:0001406 biolink:OntologyClass binucleate A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei. go-plus.json http://purl.obolibrary.org/obo/PATO_0001406 PATO:0001407 biolink:OntologyClass mononucleate A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. go-plus.json http://purl.obolibrary.org/obo/PATO_0001407 CHEBI:81463 biolink:ChemicalSubstance dTDP-alpha-D-forosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_81463 PATO:0001404 biolink:OntologyClass nucleate quality A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. go-plus.json http://purl.obolibrary.org/obo/PATO_0001404 PATO:0001405 biolink:OntologyClass anucleate A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. go-plus.json http://purl.obolibrary.org/obo/PATO_0001405 CHEBI:81461 biolink:ChemicalSubstance dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_81461 CHEBI:81462 biolink:ChemicalSubstance dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_81462 CHEBI:4188 biolink:ChemicalSubstance D-glycero-D-manno-heptose 1,7-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_4188 NCBITaxon:28261 biolink:OrganismalEntity Thermodesulfovibrio go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_28261 NCBITaxon:28262 biolink:OrganismalEntity Thermodesulfovibrio yellowstonii go-plus.json Thermodesulfurivibrio yellowstonensis|Thermodesulfovibrio yellowstonensis|Thermodesulfurivibrio yellowstonii http://purl.obolibrary.org/obo/NCBITaxon_28262 CHEBI:81474 biolink:ChemicalSubstance N-Acetyl-alpha-D-hexosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_81474 CHEBI:81471 biolink:ChemicalSubstance 7alpha-hydroxydehydroepiandrosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_81471 chebi_ph7_3 CHEBI:81485 biolink:ChemicalSubstance osthenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_81485 chebi_ph7_3 SO:0100001 biolink:SequenceFeature biochemical_region_of_peptide A region of a peptide that is involved in a biochemical function. go-plus.json biochemical region of peptide|biochemical motif|biochemical_region http://purl.obolibrary.org/obo/SO_0100001 biosapiens CHEBI:81481 biolink:ChemicalSubstance 11beta-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_81481 chebi_ph7_3 CHEBI:136183 biolink:ChemicalSubstance N-jasmonyl-L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136183 chebi_ph7_3 CHEBI:136184 biolink:ChemicalSubstance jasmonic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136184 chebi_ph7_3 NCBITaxon:28231 biolink:OrganismalEntity Geobacter go-plus.json Trichlorobacter http://purl.obolibrary.org/obo/NCBITaxon_28231 CHEBI:175763 biolink:ChemicalSubstance 2-trans,6-trans-farnesyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_175763 chebi_ph7_3 GO:0006825 biolink:BiologicalProcess copper ion transport The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006825 GO:0006826 biolink:BiologicalProcess iron ion transport The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json iron transport|ferric ion transport|iron ion import|ferric ion import|ferrous iron transport|ferrous ion transport|ferric iron transport|ferric iron import|ferric iron uptake http://purl.obolibrary.org/obo/GO_0006826 GO:0006823 biolink:BiologicalProcess obsolete heavy metal ion transport OBSOLETE. The directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. go-plus.json heavy metal ion transport http://purl.obolibrary.org/obo/GO_0006823 GO:0006824 biolink:BiologicalProcess cobalt ion transport The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json cobalt transport http://purl.obolibrary.org/obo/GO_0006824 GO:0006821 biolink:BiologicalProcess chloride transport The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006821 GO:0006822 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006822 GO:0006820 biolink:BiologicalProcess anion transport The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006820 CHEBI:32425 biolink:ChemicalSubstance (11Z)-icos-11-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32425 CHEBI:32426 biolink:ChemicalSubstance gondoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32426 chebi_ph7_3 GO:0006829 biolink:BiologicalProcess zinc ion transport The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json zinc II ion transport|zinc transport http://purl.obolibrary.org/obo/GO_0006829 GO:0006827 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006827 GO:0006828 biolink:BiologicalProcess manganese ion transport The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006828 GO:0006836 biolink:BiologicalProcess neurotransmitter transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. go-plus.json sodium:neurotransmitter transport http://purl.obolibrary.org/obo/GO_0006836 goslim_pir GO:0006837 biolink:BiologicalProcess serotonin transport The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. go-plus.json http://purl.obolibrary.org/obo/GO_0006837 GO:0006834 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006834 GO:0006835 biolink:BiologicalProcess dicarboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sodium:dicarboxylate transport http://purl.obolibrary.org/obo/GO_0006835 GO:0006832 biolink:BiologicalProcess obsolete small molecule transport OBSOLETE. (Was not defined before being made obsolete). go-plus.json small molecule transport http://purl.obolibrary.org/obo/GO_0006832 GO:0006833 biolink:BiologicalProcess water transport The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006833 GO:0006830 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006830 GO:0006831 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006831 CHEBI:32436 biolink:ChemicalSubstance D-alaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32436 CHEBI:32437 biolink:ChemicalSubstance D-alanyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32437 CHEBI:32439 biolink:ChemicalSubstance alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32439 CHEBI:32431 biolink:ChemicalSubstance L-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32431 CHEBI:32432 biolink:ChemicalSubstance L-alaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32432 CHEBI:32433 biolink:ChemicalSubstance L-alanyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32433 CHEBI:32435 biolink:ChemicalSubstance D-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32435 GO:0006838 biolink:BiologicalProcess obsolete allantoin/allantoate transport OBSOLETE. (Was not defined before being made obsolete). go-plus.json allantoin/allantoate transport http://purl.obolibrary.org/obo/GO_0006838 GO:0006839 biolink:BiologicalProcess mitochondrial transport Transport of substances into, out of or within a mitochondrion. go-plus.json mitochondrial aspartate/glutamate transport|mitochondrial sodium/calcium ion exchange|mitochondrial alpha-ketoglutarate/malate transport http://purl.obolibrary.org/obo/GO_0006839 goslim_drosophila GO:0006803 biolink:BiologicalProcess obsolete glutathione conjugation reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json glutathione conjugation reaction http://purl.obolibrary.org/obo/GO_0006803 GO:0006804 biolink:BiologicalProcess obsolete peroxidase reaction OBSOLETE. (Was not defined before being made obsolete). go-plus.json peroxidase reaction http://purl.obolibrary.org/obo/GO_0006804 GO:0006801 biolink:BiologicalProcess superoxide metabolic process The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. go-plus.json superoxide free radical metabolism|oxygen free radical metabolic process|oxygen free radical metabolism|superoxide metabolism|superoxide free radical metabolic process http://purl.obolibrary.org/obo/GO_0006801 GO:0006802 biolink:BiologicalProcess obsolete catalase reaction OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O. go-plus.json hydroperoxidase reaction|catalase reaction http://purl.obolibrary.org/obo/GO_0006802 GO:0006800 biolink:BiologicalProcess obsolete oxygen and reactive oxygen species metabolic process OBSOLETE. The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). go-plus.json oxygen and ROS metabolic process|oxygen and reactive oxygen species metabolism|oxygen and reactive oxygen intermediate metabolism|oxygen and AOS metabolism|oxygen and reactive oxidative species metabolism|oxygen and ROI metabolism|oxygen and reactive oxygen species metabolic process|oxygen and ROS metabolism|oxygen and active oxygen species metabolism http://purl.obolibrary.org/obo/GO_0006800 CHEBI:32408 biolink:ChemicalSubstance parinaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32408 CHEBI:32409 biolink:ChemicalSubstance (9Z,11E,13E,15Z)-octadecatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32409 CHEBI:32402 biolink:ChemicalSubstance catecholate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32402 GO:0006809 biolink:BiologicalProcess nitric oxide biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. go-plus.json nitric oxide anabolism|nitric oxide synthesis|nitric oxide formation|nitric oxide biosynthesis http://purl.obolibrary.org/obo/GO_0006809 GO:0006807 biolink:BiologicalProcess nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. go-plus.json nitrogen compound metabolism http://purl.obolibrary.org/obo/GO_0006807 goslim_pir|goslim_metagenomics GO:0006808 biolink:BiologicalProcess regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization. go-plus.json http://purl.obolibrary.org/obo/GO_0006808 goslim_metagenomics GO:0006805 biolink:BiologicalProcess xenobiotic metabolic process The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. Wikipedia:Xenobiotic_metabolism|Wikipedia:Drug_metabolism go-plus.json drug metabolism|drug metabolic process|xenobiotic metabolism http://purl.obolibrary.org/obo/GO_0006805 goslim_chembl|goslim_pir GO:0006806 biolink:BiologicalProcess obsolete insecticide resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json insecticide resistance http://purl.obolibrary.org/obo/GO_0006806 GO:0006814 biolink:BiologicalProcess sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sodium channel auxiliary protein activity|sodium transport|sodium:calcium exchange|sodium/potassium transport|mitochondrial sodium/calcium ion exchange|sodium:solute transport http://purl.obolibrary.org/obo/GO_0006814 GO:0006815 biolink:BiologicalProcess obsolete sodium/potassium transport OBSOLETE. (Was not defined before being made obsolete). go-plus.json sodium/potassium transport http://purl.obolibrary.org/obo/GO_0006815 GO:0006812 biolink:BiologicalProcess cation transport The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json di-, tri-valent inorganic cation transport|trivalent inorganic cation transport http://purl.obolibrary.org/obo/GO_0006812 GO:0006813 biolink:BiologicalProcess potassium ion transport The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sodium/potassium transport|potassium transport|potassium ion conductance|cellular potassium ion transport|K+ conductance|potassium conductance|low voltage-gated potassium channel auxiliary protein activity|low voltage-dependent potassium channel auxiliary protein activity http://purl.obolibrary.org/obo/GO_0006813 GO:0006810 biolink:BiologicalProcess transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. go-plus.json single-organism transport|solute:solute exchange|small molecule transport http://purl.obolibrary.org/obo/GO_0006810 goslim_generic|goslim_chembl|goslim_candida|gocheck_do_not_annotate|goslim_plant|goslim_pir|goslim_metagenomics|goslim_aspergillus GO:0006811 biolink:BiologicalProcess ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006811 goslim_yeast|goslim_pir|goslim_drosophila CHEBI:32414 biolink:ChemicalSubstance cis-parinarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32414 chebi_ph7_3 NCBITaxon:187857 biolink:OrganismalEntity Aquificae go-plus.json Aquificae http://purl.obolibrary.org/obo/NCBITaxon_187857 NCBITaxon:92860 biolink:OrganismalEntity Pleosporales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_92860 GO:0006818 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006818 GO:0006819 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006819 GO:0006816 biolink:BiologicalProcess calcium ion transport The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sodium:calcium exchange|mitochondrial sodium/calcium ion exchange|calcium transport http://purl.obolibrary.org/obo/GO_0006816 GO:0006817 biolink:BiologicalProcess phosphate ion transport The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json phosphate transport http://purl.obolibrary.org/obo/GO_0006817 CHEBI:81405 biolink:ChemicalSubstance N-Acetyldemethylphosphinothricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_81405 CHEBI:81403 biolink:ChemicalSubstance 2-phosphinomethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81403 NCBITaxon:5042 biolink:OrganismalEntity Eurotiales go-plus.json Elaphomycetales|green and blue molds http://purl.obolibrary.org/obo/NCBITaxon_5042 NCBITaxon:5020 biolink:OrganismalEntity Phaeosphaeriaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5020 GO:0031869 biolink:MolecularActivity prostacyclin receptor binding Binding to a prostacyclin receptor. go-plus.json prostacyclin receptor ligand|prostanoid IP receptor binding http://purl.obolibrary.org/obo/GO_0031869 GO:0031867 biolink:MolecularActivity EP4 subtype prostaglandin E2 receptor binding Binding to an EP4 subtype prostaglandin E2 receptor. go-plus.json prostanoid EP4 receptor binding|EP4 subtype prostaglandin E2 receptor ligand http://purl.obolibrary.org/obo/GO_0031867 GO:0031868 biolink:MolecularActivity prostaglandin F2-alpha receptor binding Binding to a prostaglandin F2-alpha receptor. go-plus.json prostanoid FP receptor binding|prostaglandin F2-alpha receptor ligand http://purl.obolibrary.org/obo/GO_0031868 GO:0031865 biolink:MolecularActivity EP2 subtype prostaglandin E2 receptor binding Binding to an EP2 subtype prostaglandin E2 receptor. go-plus.json prostanoid EP2 receptor binding|EP2 subtype prostaglandin E2 receptor ligand http://purl.obolibrary.org/obo/GO_0031865 GO:0090161 biolink:BiologicalProcess Golgi ribbon formation The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae. go-plus.json http://purl.obolibrary.org/obo/GO_0090161 GO:0031866 biolink:MolecularActivity EP3 subtype prostaglandin E2 receptor binding Binding to an EP3 subtype prostaglandin E2 receptor. go-plus.json prostanoid EP3 receptor binding|EP3 subtype prostaglandin E2 receptor ligand http://purl.obolibrary.org/obo/GO_0031866 GO:0090162 biolink:BiologicalProcess establishment of epithelial cell polarity The specification and formation of anisotropic intracellular organization of an epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090162 GO:0031863 biolink:MolecularActivity prostaglandin D2 receptor binding Binding to a prostaglandin D2 receptor. go-plus.json prostanoid DP receptor binding|prostaglandin D2 receptor ligand http://purl.obolibrary.org/obo/GO_0031863 GO:0031864 biolink:MolecularActivity EP1 subtype prostaglandin E2 receptor binding Binding to an EP1 subtype prostaglandin E2 receptor. go-plus.json prostanoid EP1 receptor binding|EP1 subtype prostaglandin E2 receptor ligand http://purl.obolibrary.org/obo/GO_0031864 GO:0090160 biolink:BiologicalProcess Golgi to lysosome transport The directed movement of substances from the Golgi to lysosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0090160 UBERON:0007806 biolink:AnatomicalEntity connecting stalk A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007806 UBERON:0007807 biolink:AnatomicalEntity connecting stalk vasculature A vasculature that is part of a connecting stalk. go-plus.json connecting stalk blood vessels|connecting stalk blood vessel|vasculature of connecting stalk http://purl.obolibrary.org/obo/UBERON_0007807 UBERON:0007808 biolink:AnatomicalEntity adipose tissue of abdominal region Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots. go-plus.json abdominal fat|abdominal adipose tissue|intra-abdominal fat http://purl.obolibrary.org/obo/UBERON_0007808 GO:0016228 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016228 GO:0016229 biolink:MolecularActivity steroid dehydrogenase activity Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0016229 UBERON:0007811 biolink:AnatomicalEntity craniocervical region The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. go-plus.json head or neck|cephalic part of animal|cephalic region|cephalic area|head and neck http://purl.obolibrary.org/obo/UBERON_0007811 GO:0016224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016224 UBERON:0007812 biolink:AnatomicalEntity post-anal tail A tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton. go-plus.json postanal tail|muscular postanal tail|post-vent region|post-anal fin tail http://purl.obolibrary.org/obo/UBERON_0007812 GO:0016225 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016225 GO:0016226 biolink:BiologicalProcess iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. go-plus.json iron-sulphur cluster assembly|iron-sulfur cluster biosynthesis http://purl.obolibrary.org/obo/GO_0016226 goslim_metagenomics|goslim_pombe GO:0016227 biolink:MolecularActivity obsolete tRNA sulfurtransferase activity OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide. go-plus.json transfer RNA sulfurtransferase activity|tRNA sulfurtransferase activity|transfer ribonucleate sulfurtransferase activity|L-cysteine:tRNA sulfurtransferase activity|ribonucleate sulfurtransferase activity|transfer RNA thiolase activity|RNA sulfurtransferase activity|tRNA sulphurtransferase activity http://purl.obolibrary.org/obo/GO_0016227 GO:0090165 biolink:BiologicalProcess regulation of secretion by asymmetric Golgi ribbon formation The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090165 GO:0031861 biolink:MolecularActivity prolactin-releasing peptide receptor binding Binding to a prolactin-releasing peptide receptor. go-plus.json prolactin-releasing peptide receptor ligand http://purl.obolibrary.org/obo/GO_0031861 GO:0016220 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016220 GO:0090166 biolink:BiologicalProcess Golgi disassembly A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. go-plus.json http://purl.obolibrary.org/obo/GO_0090166 GO:0031862 biolink:MolecularActivity prostanoid receptor binding Binding to a prostanoid receptor. go-plus.json prostanoid receptor ligand http://purl.obolibrary.org/obo/GO_0031862 GO:0090163 biolink:BiologicalProcess establishment of epithelial cell planar polarity The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0090163 GO:0016222 biolink:CellularComponent procollagen-proline 4-dioxygenase complex A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase. go-plus.json prolyl 4-hydroxylase complex|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex http://purl.obolibrary.org/obo/GO_0016222 GO:0090164 biolink:BiologicalProcess asymmetric Golgi ribbon formation The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0090164 GO:0016223 biolink:MolecularActivity beta-alanine-pyruvate transaminase activity Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine. MetaCyc:2.6.1.18-RXN|RHEA:14077|Reactome:R-HSA-909776|EC:2.6.1.18 go-plus.json omega-amino acid--pyruvate aminotransferase activity|beta-alanine--pyruvate aminotransferase activity|beta-alanine-pyruvate aminotransferase activity|L-alanine:3-oxopropanoate aminotransferase activity|beta-alanine-alpha-alanine transaminase activity http://purl.obolibrary.org/obo/GO_0016223 GO:0031860 biolink:BiologicalProcess telomeric 3' overhang formation The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans. go-plus.json telomere end processing|telomere 3'-end processing http://purl.obolibrary.org/obo/GO_0031860 GO:0090169 biolink:BiologicalProcess regulation of spindle assembly Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. go-plus.json regulation of spindle formation http://purl.obolibrary.org/obo/GO_0090169 GO:0090167 biolink:BiologicalProcess Golgi distribution to daughter cells Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0090167 GO:0090168 biolink:BiologicalProcess Golgi reassembly The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. go-plus.json http://purl.obolibrary.org/obo/GO_0090168 GO:0031858 biolink:MolecularActivity pituitary adenylate cyclase-activating polypeptide receptor binding Binding to a pituitary adenylate cyclase-activating polypeptide receptor. go-plus.json PACAP receptor binding|pituitary adenylate cyclase-activating peptide receptor ligand|pituitary adenylate cyclase activating peptide receptor binding http://purl.obolibrary.org/obo/GO_0031858 GO:0031859 biolink:MolecularActivity platelet activating factor receptor binding Binding to a platelet activating factor receptor. go-plus.json platelet activating factor receptor ligand http://purl.obolibrary.org/obo/GO_0031859 GO:0031856 biolink:MolecularActivity parathyroid hormone receptor binding Binding to a parathyroid hormone receptor. go-plus.json parathyroid hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031856 GO:0031857 biolink:MolecularActivity type 1 parathyroid hormone receptor binding Binding to a type 1 parathyroid hormone receptor. go-plus.json type 1 parathyroid hormone receptor ligand http://purl.obolibrary.org/obo/GO_0031857 GO:0090172 biolink:BiologicalProcess microtubule cytoskeleton organization involved in homologous chromosome segregation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis. go-plus.json microtubule cytoskeleton organisation involved in homologous chromosome segregation|microtubule organization involved in chromosome pairing http://purl.obolibrary.org/obo/GO_0090172 GO:0031854 biolink:MolecularActivity orexigenic neuropeptide QRFP receptor binding Binding to an orexigenic neuropeptide QRFP receptor. go-plus.json orexigenic neuropeptide QRFP receptor ligand http://purl.obolibrary.org/obo/GO_0031854 GO:0031855 biolink:MolecularActivity oxytocin receptor binding Binding to an oxytocin receptor. go-plus.json oxytocin receptor ligand http://purl.obolibrary.org/obo/GO_0031855 GO:0090173 biolink:BiologicalProcess regulation of synaptonemal complex assembly Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0090173 GO:0031852 biolink:MolecularActivity mu-type opioid receptor binding Binding to a mu-type opioid receptor. go-plus.json morphine receptor binding|mu-type opioid receptor ligand http://purl.obolibrary.org/obo/GO_0031852 GO:0090170 biolink:BiologicalProcess regulation of Golgi inheritance Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0090170 GO:0090171 biolink:BiologicalProcess chondrocyte morphogenesis The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0090171 GO:0031853 biolink:MolecularActivity nociceptin receptor binding Binding to a nociceptin receptor. go-plus.json nociceptin receptor ligand http://purl.obolibrary.org/obo/GO_0031853 GO:0016239 biolink:BiologicalProcess positive regulation of macroautophagy Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. go-plus.json activation of macroautophagy|up regulation of macroautophagy|upregulation of macroautophagy|positive regulation of starvation-induced autophagy|stimulation of macroautophagy|up-regulation of macroautophagy http://purl.obolibrary.org/obo/GO_0016239 CHEBI:136219 biolink:ChemicalSubstance lysophosphatidylglycerol 18:1/0:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136219 GO:0016235 biolink:CellularComponent aggresome An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. Wikipedia:Aggresome go-plus.json http://purl.obolibrary.org/obo/GO_0016235 GO:0016236 biolink:BiologicalProcess macroautophagy The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded. go-plus.json autophagy http://purl.obolibrary.org/obo/GO_0016236 GO:0016237 biolink:BiologicalProcess lysosomal microautophagy The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0016237 CHEBI:136218 biolink:ChemicalSubstance lysophosphatidylglycerol 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136218 GO:0016238 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016238 GO:0090176 biolink:BiologicalProcess microtubule cytoskeleton organization involved in establishment of planar polarity A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity. go-plus.json microtubule cytoskeleton organisation involved in establishment of planar polarity http://purl.obolibrary.org/obo/GO_0090176 GO:0016231 biolink:MolecularActivity beta-N-acetylglucosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides. go-plus.json http://purl.obolibrary.org/obo/GO_0016231 GO:0031850 biolink:MolecularActivity delta-type opioid receptor binding Binding to a delta-type opioid receptor. go-plus.json enkephalin receptor binding|delta-type opioid receptor ligand http://purl.obolibrary.org/obo/GO_0031850 GO:0016232 biolink:MolecularActivity HNK-1 sulfotransferase activity Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R). Reactome:R-HSA-6786048 go-plus.json HNK-1 sulphotransferase activity http://purl.obolibrary.org/obo/GO_0016232 GO:0031851 biolink:MolecularActivity kappa-type opioid receptor binding Binding to a kappa-type opioid receptor. go-plus.json kappa-type opioid receptor ligand|dynorphin receptor binding http://purl.obolibrary.org/obo/GO_0031851 GO:0090177 biolink:BiologicalProcess establishment of planar polarity involved in neural tube closure Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0090177 GO:0090174 biolink:BiologicalProcess organelle membrane fusion The joining of two lipid bilayers to form a single organelle membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0090174 GO:0016233 biolink:BiologicalProcess telomere capping A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins. go-plus.json telomere end protection http://purl.obolibrary.org/obo/GO_0016233 GO:0090175 biolink:BiologicalProcess regulation of establishment of planar polarity Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. go-plus.json http://purl.obolibrary.org/obo/GO_0090175 GO:0016234 biolink:CellularComponent inclusion body A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers. NIF_Subcellular:sao120573470|Wikipedia:Inclusion_bodies go-plus.json neuronal cytoplasmic inclusion|cellular inclusion http://purl.obolibrary.org/obo/GO_0016234 GO:0090178 biolink:BiologicalProcess regulation of establishment of planar polarity involved in neural tube closure Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0090178 GO:0090179 biolink:BiologicalProcess planar cell polarity pathway involved in neural tube closure The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure. go-plus.json http://purl.obolibrary.org/obo/GO_0090179 GO:0016230 biolink:MolecularActivity sphingomyelin phosphodiesterase activator activity Increases the activity of the enzyme sphingomyelin phosphodiesterase. go-plus.json neutral sphingomyelinase activator http://purl.obolibrary.org/obo/GO_0016230 GO:0031847 biolink:MolecularActivity type 1 neurotensin receptor binding Binding to a type 1 neurotensin receptor. go-plus.json type 1 neurotensin receptor ligand http://purl.obolibrary.org/obo/GO_0031847 GO:0031848 biolink:BiologicalProcess protection from non-homologous end joining at telomere A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse. go-plus.json protection from NHEJ-mediated telomere fusion http://purl.obolibrary.org/obo/GO_0031848 GO:0031845 biolink:MolecularActivity type 5 neuropeptide Y receptor binding Binding to a type 5 neuropeptide Y receptor. go-plus.json type 5 neuropeptide Y receptor ligand http://purl.obolibrary.org/obo/GO_0031845 GO:0006889 biolink:BiologicalProcess obsolete regulation of calcium in ER OBSOLETE. Any process that modulates the concentration of calcium in the endoplasmic reticulum. go-plus.json regulation of calcium in ER http://purl.obolibrary.org/obo/GO_0006889 GO:0031846 biolink:MolecularActivity neurotensin receptor binding Binding to a neurotensin receptor. go-plus.json neurotensin receptor ligand http://purl.obolibrary.org/obo/GO_0031846 GO:0006887 biolink:BiologicalProcess exocytosis A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. Wikipedia:Exocytosis go-plus.json nonselective vesicle exocytosis|vesicle exocytosis http://purl.obolibrary.org/obo/GO_0006887 goslim_yeast GO:0031843 biolink:MolecularActivity type 2 neuropeptide Y receptor binding Binding to a type 2 neuropeptide Y receptor. go-plus.json type 2 neuropeptide Y receptor ligand http://purl.obolibrary.org/obo/GO_0031843 GO:0090140 biolink:BiologicalProcess regulation of mitochondrial fission Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. go-plus.json regulation of mitochondrial division http://purl.obolibrary.org/obo/GO_0090140 GO:0006888 biolink:BiologicalProcess endoplasmic reticulum to Golgi vesicle-mediated transport The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi. go-plus.json anterograde (ER to Golgi) transport|rough endoplasmic reticulum to cis-Golgi transport|rough ER to cis-Golgi vesicle-mediated transport|ER to Golgi transport|endoplasmic reticulum to Golgi vesicle-mediated transport|anterograde transport, ER to Golgi|endoplasmic reticulum to Golgi transport|ER to Golgi vesicle-mediated transport|anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi|rough ER to cis-Golgi transport|rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|anterograde vesicle-mediated transport, ER to Golgi|anterograde transport, endoplasmic reticulum to Golgi http://purl.obolibrary.org/obo/GO_0006888 GO:0031844 biolink:MolecularActivity type 4 neuropeptide Y receptor binding Binding to a type 4 neuropeptide Y receptor. go-plus.json type 4 neuropeptide Y receptor ligand|pancreatic polypeptide receptor binding http://purl.obolibrary.org/obo/GO_0031844 GO:0006885 biolink:BiologicalProcess regulation of pH Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. go-plus.json hydrogen ion homeostasis http://purl.obolibrary.org/obo/GO_0006885 GO:0031841 biolink:MolecularActivity neuropeptide Y receptor binding Binding to a neuropeptide Y receptor. go-plus.json NPY receptor binding|neuropeptide Y receptor ligand http://purl.obolibrary.org/obo/GO_0031841 GO:0031842 biolink:MolecularActivity type 1 neuropeptide Y receptor binding Binding to a type 1 neuropeptide Y receptor. go-plus.json type 1 neuropeptide Y receptor ligand http://purl.obolibrary.org/obo/GO_0031842 GO:0006886 biolink:BiologicalProcess intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. go-plus.json copper-induced intracellular protein transport http://purl.obolibrary.org/obo/GO_0006886 GO:0006883 biolink:BiologicalProcess cellular sodium ion homeostasis Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0006883 GO:0006884 biolink:BiologicalProcess cell volume homeostasis Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell. go-plus.json regulation of cell volume http://purl.obolibrary.org/obo/GO_0006884 GO:0006881 biolink:BiologicalProcess extracellular sequestering of iron ion The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system. go-plus.json extracellular iron ion retention|extracellular iron ion storage|extracellular retention of iron ion|extracellular iron ion sequestering|extracellular storage of iron ion|extracellular iron ion sequestration|extracellular sequestration of iron ion http://purl.obolibrary.org/obo/GO_0006881 GO:0006882 biolink:BiologicalProcess cellular zinc ion homeostasis Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell. go-plus.json zinc homeostasis http://purl.obolibrary.org/obo/GO_0006882 GO:0006880 biolink:BiologicalProcess intracellular sequestering of iron ion The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system. go-plus.json intracellular iron ion storage|intracellular retention of iron ion|intracellular iron ion sequestering|intracellular storage of iron ion|intracellular iron ion sequestration|intracellular sequestration of iron ion|intracellular iron ion retention http://purl.obolibrary.org/obo/GO_0006880 GO:0031849 biolink:MolecularActivity olfactory receptor binding Binding to an olfactory receptor. go-plus.json olfactory receptor ligand http://purl.obolibrary.org/obo/GO_0031849 GO:0016206 biolink:MolecularActivity catechol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol. Reactome:R-HSA-175983|EC:2.1.1.6|Reactome:R-HSA-8955010|MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:catechol O-methyltransferase activity|S-COMT (soluble form of catechol-O-methyltransferase)|COMT II|MB-COMT (membrane-bound form of catechol-O-methyltransferase)|catecholamine O-methyltransferase activity|COMT I|catechol methyltransferase activity http://purl.obolibrary.org/obo/GO_0016206 CHEBI:32483 biolink:ChemicalSubstance glutamic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32483 GO:0016207 biolink:MolecularActivity 4-coumarate-CoA ligase activity Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA. KEGG_REACTION:R01616|MetaCyc:4-COUMARATE--COA-LIGASE-RXN|EC:6.2.1.12|RHEA:19641 go-plus.json sinapoyl coenzyme A synthetase activity|p-hydroxycinnamoyl coenzyme A synthetase activity|4-coumarate-CoA synthetase activity|4-coumaroyl-CoA synthase activity|p-coumaryl-CoA synthetase activity|feruloyl CoA ligase activity|p-coumaryl-CoA ligase activity|hydroxycinnamate:CoA ligase activity|4-coumaryl-CoA synthetase activity|p-coumaryl coenzyme A synthetase activity|p-coumaroyl CoA ligase activity|4-coumarate:coenzyme A ligase activity|4-coumarate:CoA ligase activity|4-coumarate:CoA ligase (AMP-forming)|4-coumaroyl-CoA synthetase activity|p-hydroxycinnamic acid:CoA ligase activity|4CL|caffeolyl coenzyme A synthetase activity|feruloyl coenzyme A synthetase activity|hydroxycinnamoyl CoA synthetase activity http://purl.obolibrary.org/obo/GO_0016207 CHEBI:32484 biolink:ChemicalSubstance glutamate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32484 GO:0090149 biolink:BiologicalProcess mitochondrial membrane fission A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission. go-plus.json mitochondrial membrane scission|membrane fission involved in mitochondrial fission http://purl.obolibrary.org/obo/GO_0090149 GO:0016208 biolink:MolecularActivity AMP binding Binding to AMP, adenosine monophosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0016208 GO:0016209 biolink:MolecularActivity antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. go-plus.json http://purl.obolibrary.org/obo/GO_0016209 goslim_pir|goslim_metagenomics CHEBI:32486 biolink:ChemicalSubstance L-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32486 CHEBI:32487 biolink:ChemicalSubstance L-phenylalaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32487 GO:0016202 biolink:BiologicalProcess regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of striated muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0016202 GO:0016203 biolink:BiologicalProcess muscle attachment The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall). go-plus.json http://purl.obolibrary.org/obo/GO_0016203 GO:0016204 biolink:BiologicalProcess determination of muscle attachment site The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site. go-plus.json http://purl.obolibrary.org/obo/GO_0016204 GO:0016205 biolink:MolecularActivity selenocysteine methyltransferase activity Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine. MetaCyc:RXN-11061|RHEA:26341|EC:2.1.1.280 go-plus.json http://purl.obolibrary.org/obo/GO_0016205 GO:0090143 biolink:BiologicalProcess nucleoid organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined. go-plus.json nucleoid organisation http://purl.obolibrary.org/obo/GO_0090143 GO:0031840 biolink:MolecularActivity type 2 neuromedin U receptor binding Binding to a type 2 neuromedin U receptor. go-plus.json type 2 neuromedin U receptor ligand http://purl.obolibrary.org/obo/GO_0031840 GO:0090144 biolink:BiologicalProcess mitochondrial nucleoid organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined. go-plus.json mitochondrial nucleoid organisation http://purl.obolibrary.org/obo/GO_0090144 GO:0016200 biolink:BiologicalProcess synaptic target attraction The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets. go-plus.json http://purl.obolibrary.org/obo/GO_0016200 GO:0090141 biolink:BiologicalProcess positive regulation of mitochondrial fission Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. go-plus.json positive regulation of mitochondrial division http://purl.obolibrary.org/obo/GO_0090141 GO:0016201 biolink:BiologicalProcess synaptic target inhibition The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source. go-plus.json http://purl.obolibrary.org/obo/GO_0016201 GO:0090142 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090142 GO:0090147 biolink:BiologicalProcess obsolete regulation of establishment of mitochondrion localization involved in mitochondrial fission OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission. go-plus.json regulation of establishment of mitochondrion localisation involved in mitochondrial fission|regulation of mitochondrial localization involved in mitochondrial fission http://purl.obolibrary.org/obo/GO_0090147 GO:0090148 biolink:BiologicalProcess membrane fission A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes. go-plus.json membrane scission http://purl.obolibrary.org/obo/GO_0090148 CHEBI:32480 biolink:ChemicalSubstance D-gamma-glutamyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32480 GO:0090145 biolink:BiologicalProcess obsolete mitochondrial nucleoid organization involved in mitochondrial fission OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division. go-plus.json mitochondrial nucleoid organisation involved in mitochondrial fission http://purl.obolibrary.org/obo/GO_0090145 GO:0090146 biolink:BiologicalProcess obsolete establishment of mitochondrion localization involved in mitochondrial fission OBSOLETE. The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission. go-plus.json establishment of mitochondrion localisation involved in mitochondrial fission|mitochondrial localization involved in mitochondrial fission http://purl.obolibrary.org/obo/GO_0090146 NCBITaxon:5052 biolink:OrganismalEntity Aspergillus go-plus.json Chaetosartorya|Polypaecilum|Phialosimplex|Petromyces http://purl.obolibrary.org/obo/NCBITaxon_5052 CHEBI:32482 biolink:ChemicalSubstance D-glutamo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32482 GO:0031836 biolink:MolecularActivity neuromedin K receptor binding Binding to a neuromedin K receptor. go-plus.json neuromedin K receptor ligand|neurokinin-B receptor binding http://purl.obolibrary.org/obo/GO_0031836 GO:0031837 biolink:MolecularActivity substance K receptor binding Binding to a substance K receptor. go-plus.json neurokinin-A receptor binding|substance K receptor ligand http://purl.obolibrary.org/obo/GO_0031837 GO:0031834 biolink:MolecularActivity neurokinin receptor binding Binding to a neurokinin receptor. go-plus.json neurokinin receptor ligand http://purl.obolibrary.org/obo/GO_0031834 GO:0031835 biolink:MolecularActivity substance P receptor binding Binding to a substance P receptor. go-plus.json neurokinin-1 receptor binding|substance P receptor ligand http://purl.obolibrary.org/obo/GO_0031835 GO:0090150 biolink:BiologicalProcess establishment of protein localization to membrane The directed movement of a protein to a specific location in a membrane. go-plus.json establishment of protein localisation in membrane|establishment of protein localization in membrane http://purl.obolibrary.org/obo/GO_0090150 GO:0031832 biolink:MolecularActivity type 6 serotonin receptor binding Binding to a type 6 serotonin receptor. go-plus.json 5-hydroxytryptamine 6 receptor binding|type 6 serotonin receptor ligand http://purl.obolibrary.org/obo/GO_0031832 GO:0006898 biolink:BiologicalProcess receptor-mediated endocytosis An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. Wikipedia:Receptor-mediated_endocytosis go-plus.json receptor mediated endocytosis http://purl.obolibrary.org/obo/GO_0006898 GO:0031833 biolink:MolecularActivity type 7 serotonin receptor binding Binding to a type 7 serotonin receptor. go-plus.json 5-hydroxytryptamine 7 receptor binding|type 7 serotonin receptor ligand http://purl.obolibrary.org/obo/GO_0031833 GO:0090151 biolink:BiologicalProcess establishment of protein localization to mitochondrial membrane The directed movement of a protein to a specific location in the mitochondrial membrane. go-plus.json establishment of protein localisation in mitochondrial membrane|establishment of protein localization in mitochondrial membrane http://purl.obolibrary.org/obo/GO_0090151 GO:0006899 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006899 GO:0006896 biolink:BiologicalProcess Golgi to vacuole transport The directed movement of substances from the Golgi to the vacuole. go-plus.json Golgi to vacuole vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0006896 GO:0031830 biolink:MolecularActivity type 5A serotonin receptor binding Binding to a type 5A serotonin receptor. go-plus.json type 5A serotonin receptor ligand|5-hydroxytryptamine 5A receptor binding http://purl.obolibrary.org/obo/GO_0031830 GO:0006897 biolink:BiologicalProcess endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. Wikipedia:Endocytosis go-plus.json vesicle endocytosis|plasma membrane invagination|endocytic import into cell|nonselective vesicle endocytosis http://purl.obolibrary.org/obo/GO_0006897 goslim_yeast GO:0031831 biolink:MolecularActivity type 5B serotonin receptor binding Binding to a type 5B serotonin receptor. go-plus.json type 5B serotonin receptor ligand|5-hydroxytryptamine 5B receptor binding http://purl.obolibrary.org/obo/GO_0031831 GO:0006894 biolink:BiologicalProcess obsolete Golgi to secretory vesicle transport OBSOLETE. The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release. go-plus.json Golgi to secretory vesicle transport|Golgi to secretory vesicle transport, vesicle-mediated http://purl.obolibrary.org/obo/GO_0006894 GO:0006895 biolink:BiologicalProcess Golgi to endosome transport The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes. go-plus.json TGN to endosome transport|Golgi to endosome vesicle-mediated transport|trans-Golgi to endosome transport http://purl.obolibrary.org/obo/GO_0006895 GO:0006892 biolink:BiologicalProcess post-Golgi vesicle-mediated transport The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. go-plus.json post-Golgi transport http://purl.obolibrary.org/obo/GO_0006892 GO:0006893 biolink:BiologicalProcess Golgi to plasma membrane transport The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. go-plus.json Golgi to plasma membrane vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0006893 GO:0006890 biolink:BiologicalProcess retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. go-plus.json cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|retrograde vesicle-mediated transport, Golgi to ER|cis-Golgi to rough ER vesicle-mediated transport|cis-Golgi to rough ER transport|retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum|cis-Golgi to rough endoplasmic reticulum transport|retrograde transport, Golgi to ER|retrograde (Golgi to ER) transport|retrograde transport, Golgi to endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0006890 GO:0006891 biolink:BiologicalProcess intra-Golgi vesicle-mediated transport The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network). go-plus.json intra-Golgi transport http://purl.obolibrary.org/obo/GO_0006891 GO:0031838 biolink:CellularComponent haptoglobin-hemoglobin complex A protein complex formed by the stable binding of a haptoglobin to hemoglobin. go-plus.json http://purl.obolibrary.org/obo/GO_0031838 GO:0031839 biolink:MolecularActivity type 1 neuromedin U receptor binding Binding to a type 1 neuromedin U receptor. go-plus.json type 1 neuromedin U receptor ligand http://purl.obolibrary.org/obo/GO_0031839 GO:0016217 biolink:MolecularActivity N-ethylammeline chlorohydrolase activity Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+. MetaCyc:R465-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0016217 CHEBI:32494 biolink:ChemicalSubstance D-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32494 GO:0016218 biolink:MolecularActivity obsolete polyketide synthase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json polyketide synthase activity http://purl.obolibrary.org/obo/GO_0016218 CHEBI:32495 biolink:ChemicalSubstance D-phenylalaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32495 GO:0016219 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016219 GO:0016213 biolink:MolecularActivity linoleoyl-CoA desaturase activity Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O. MetaCyc:1.14.19.3-RXN|Reactome:R-HSA-2046096|EC:1.14.19.3|Reactome:R-HSA-2046099|Reactome:R-HSA-2046097|Reactome:R-HSA-2046084|RHEA:22196 go-plus.json linoleic acid desaturase activity|delta6-acyl CoA desaturase activity|linoleoyl CoA desaturase activity|fatty acid delta6-desaturase activity|delta6-desaturase activity|delta(6)-fatty acyl-CoA desaturase activity|fatty acid 6-desaturase activity|long-chain fatty acid delta(6)-desaturase activity|delta6-fatty acyl-CoA desaturase activity|linoleate desaturase activity|long-chain fatty acid delta6-desaturase activity|linoleoyl-coenzyme A desaturase activity|fatty acid delta(6)-desaturase activity|linoleic desaturase activity|delta(6)-desaturase activity|delta(6)-acyl CoA desaturase activity http://purl.obolibrary.org/obo/GO_0016213 GO:0016214 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0016214 GO:0016215 biolink:MolecularActivity acyl-CoA desaturase activity Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O. go-plus.json CoA desaturase activity http://purl.obolibrary.org/obo/GO_0016215 GO:0016216 biolink:MolecularActivity isopenicillin-N synthase activity Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N. EC:1.21.3.1|RHEA:22428|MetaCyc:1.21.3.1-RXN|KEGG_REACTION:R04872 go-plus.json isopenicillin N synthase activity|N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)|isopenicillin-N synthetase activity http://purl.obolibrary.org/obo/GO_0016216 GO:0090154 biolink:BiologicalProcess positive regulation of sphingolipid biosynthetic process Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). go-plus.json http://purl.obolibrary.org/obo/GO_0090154 GO:0016210 biolink:MolecularActivity naringenin-chalcone synthase activity Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2. MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN|RHEA:11128|EC:2.3.1.74 go-plus.json malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|DOCS http://purl.obolibrary.org/obo/GO_0016210 GO:0090155 biolink:BiologicalProcess negative regulation of sphingolipid biosynthetic process Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). go-plus.json negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis http://purl.obolibrary.org/obo/GO_0090155 GO:0090152 biolink:BiologicalProcess establishment of protein localization to mitochondrial membrane involved in mitochondrial fission The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission. go-plus.json establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission|establishment of protein localization in mitochondrial membrane involved in mitochondrial fission http://purl.obolibrary.org/obo/GO_0090152 GO:0016211 biolink:MolecularActivity ammonia ligase activity Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. EC:6.3.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0016211 GO:0016212 biolink:MolecularActivity kynurenine-oxoglutarate transaminase activity Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate. Reactome:R-HSA-901097|Reactome:R-HSA-893596|Reactome:R-HSA-893583|RHEA:20964|MetaCyc:2.6.1.7-RXN|EC:2.6.1.7 go-plus.json L-kynurenine aminotransferase activity|kynurenine transaminase (cyclizing)|kynurenine aminotransferase activity|L-kynurenine:2-oxoglutarate aminotransferase activity|kynurenine--oxoglutarate aminotransferase activity|kynurenine 2-oxoglutarate transaminase activity|kynurenine-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0016212 GO:0090153 biolink:BiologicalProcess regulation of sphingolipid biosynthetic process Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). go-plus.json http://purl.obolibrary.org/obo/GO_0090153 GO:0090158 biolink:BiologicalProcess endoplasmic reticulum membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane. go-plus.json endoplasmic reticulum membrane organisation http://purl.obolibrary.org/obo/GO_0090158 GO:0090159 biolink:BiologicalProcess sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization. go-plus.json sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation http://purl.obolibrary.org/obo/GO_0090159 GO:0090156 biolink:BiologicalProcess cellular sphingolipid homeostasis Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090156 GO:0090157 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090157 GO:0031825 biolink:MolecularActivity type 1F serotonin receptor binding Binding to a type 1F serotonin receptor. go-plus.json type 1F serotonin receptor ligand|5-hydroxytryptamine 1F receptor binding http://purl.obolibrary.org/obo/GO_0031825 GO:0006869 biolink:BiologicalProcess lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. go-plus.json http://purl.obolibrary.org/obo/GO_0006869 goslim_pir|goslim_drosophila|goslim_yeast GO:0031826 biolink:MolecularActivity type 2A serotonin receptor binding Binding to a type 2A serotonin receptor. go-plus.json type 2A serotonin receptor ligand|5-hydroxytryptamine 2A receptor binding http://purl.obolibrary.org/obo/GO_0031826 GO:0031823 biolink:MolecularActivity type 1D serotonin receptor binding Binding to a type 1D serotonin receptor. go-plus.json 5-hydroxytryptamine 1D receptor binding|type 1D serotonin receptor ligand http://purl.obolibrary.org/obo/GO_0031823 GO:0006867 biolink:BiologicalProcess asparagine transport The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-asparagine transport http://purl.obolibrary.org/obo/GO_0006867 GO:0031824 biolink:MolecularActivity type 1E serotonin receptor binding Binding to a type 1E serotonin receptor. go-plus.json 5-hydroxytryptamine 1E receptor binding|type 1E serotonin receptor ligand http://purl.obolibrary.org/obo/GO_0031824 GO:0006868 biolink:BiologicalProcess glutamine transport The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-glutamine transport http://purl.obolibrary.org/obo/GO_0006868 GO:0006865 biolink:BiologicalProcess amino acid transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006865 goslim_pir|goslim_yeast GO:0031821 biolink:MolecularActivity G protein-coupled serotonin receptor binding Binding to a metabotropic serotonin receptor. go-plus.json metabotropic serotonin receptor ligand|metabotropic 5-hydroxytryptamine receptor binding|metabotropic serotonin receptor binding|G-protein coupled serotonin receptor binding http://purl.obolibrary.org/obo/GO_0031821 GO:0031822 biolink:MolecularActivity type 1B serotonin receptor binding Binding to a type 1B serotonin receptor. go-plus.json 5-hydroxytryptamine 1B receptor binding|type 1B serotonin receptor ligand http://purl.obolibrary.org/obo/GO_0031822 GO:0006866 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006866 GO:0006863 biolink:BiologicalProcess purine nucleobase transport The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json purine base transport|purine base transmembrane transport|purine transport|purine transmembrane transport http://purl.obolibrary.org/obo/GO_0006863 GO:0031820 biolink:MolecularActivity P2Y11 nucleotide receptor binding Binding to a P2Y11 nucleotide receptor. go-plus.json P2Y11 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031820 GO:0006864 biolink:BiologicalProcess pyrimidine nucleotide transport The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0006864 GO:0006861 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006861 GO:0006862 biolink:BiologicalProcess nucleotide transport The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0006862 GO:0006860 biolink:BiologicalProcess extracellular amino acid transport The directed extracellular movement of amino acids. go-plus.json http://purl.obolibrary.org/obo/GO_0006860 GO:0031829 biolink:MolecularActivity type 4 serotonin receptor binding Binding to a type 4 serotonin receptor. go-plus.json type 4 serotonin receptor ligand|5-hydroxytryptamine 4 receptor binding http://purl.obolibrary.org/obo/GO_0031829 GO:0031827 biolink:MolecularActivity type 2B serotonin receptor binding Binding to a type 2B serotonin receptor. go-plus.json type 2B serotonin receptor ligand|5-hydroxytryptamine 2B receptor binding http://purl.obolibrary.org/obo/GO_0031827 GO:0031828 biolink:MolecularActivity type 2C serotonin receptor binding Binding to a type 2C serotonin receptor. go-plus.json type 2C serotonin receptor ligand|5-hydroxytryptamine 2C receptor binding http://purl.obolibrary.org/obo/GO_0031828 CHEBI:32461 biolink:ChemicalSubstance cysteinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32461 CHEBI:32462 biolink:ChemicalSubstance L-alpha-aspartyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32462 CHEBI:32466 biolink:ChemicalSubstance D-alpha-aspartyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32466 CHEBI:32460 biolink:ChemicalSubstance cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32460 GO:0031814 biolink:MolecularActivity P2Y4 nucleotide receptor binding Binding to a P2Y4 nucleotide receptor. go-plus.json P2Y4 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031814 GO:0031815 biolink:MolecularActivity P2Y5 nucleotide receptor binding Binding to a P2Y5 nucleotide receptor. go-plus.json P2Y5 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031815 GO:0031812 biolink:MolecularActivity P2Y1 nucleotide receptor binding Binding to a P2Y1 nucleotide receptor. go-plus.json P2Y1 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031812 GO:0006878 biolink:BiologicalProcess cellular copper ion homeostasis Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell. go-plus.json copper homeostasis http://purl.obolibrary.org/obo/GO_0006878 GO:0031813 biolink:MolecularActivity P2Y2 nucleotide receptor binding Binding to a P2Y2 nucleotide receptor. go-plus.json P2Y2 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031813 GO:0006879 biolink:BiologicalProcess cellular iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell. go-plus.json iron homeostasis http://purl.obolibrary.org/obo/GO_0006879 GO:0006876 biolink:BiologicalProcess cellular cadmium ion homeostasis Any process involved in the maintenance of an internal steady state of cadmium ions at the level of a cell. go-plus.json cadmium homeostasis http://purl.obolibrary.org/obo/GO_0006876 GO:0031810 biolink:MolecularActivity H4 histamine receptor binding Binding to a H4 histamine receptor. go-plus.json H4 histamine receptor ligand http://purl.obolibrary.org/obo/GO_0031810 GO:0006877 biolink:BiologicalProcess cellular cobalt ion homeostasis Any process involved in the maintenance of an internal steady state of cobalt ions at the level of a cell. go-plus.json cobalt homeostasis http://purl.obolibrary.org/obo/GO_0006877 GO:0031811 biolink:MolecularActivity G protein-coupled nucleotide receptor binding Binding to a G protein-coupled (metabotropic) nucleotide receptor. go-plus.json metabotropic nucleotide receptor ligand|G-protein coupled nucleotide receptor binding|metabotropic nucleotide receptor binding|P2Y receptor binding http://purl.obolibrary.org/obo/GO_0031811 GO:0006874 biolink:BiologicalProcess cellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. go-plus.json regulation of calcium ion concentration http://purl.obolibrary.org/obo/GO_0006874 GO:0006875 biolink:BiologicalProcess cellular metal ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell. go-plus.json cellular heavy metal ion homeostasis http://purl.obolibrary.org/obo/GO_0006875 GO:0006872 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006872 UBERON:0007838 biolink:AnatomicalEntity spinal cord white commissure go-plus.json white commissure of spinal cord http://purl.obolibrary.org/obo/UBERON_0007838 GO:0006873 biolink:BiologicalProcess cellular ion homeostasis Any process involved in the maintenance of an internal steady state of ions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0006873 goslim_yeast GO:0006870 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006870 GO:0006871 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006871 GO:0031818 biolink:MolecularActivity P2Y9 nucleotide receptor binding Binding to a P2Y9 nucleotide receptor. go-plus.json P2Y9 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031818 GO:0031819 biolink:MolecularActivity P2Y10 nucleotide receptor binding Binding to a P2Y10 nucleotide receptor. go-plus.json P2Y10 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031819 GO:0031816 biolink:MolecularActivity P2Y6 nucleotide receptor binding Binding to a P2Y6 nucleotide receptor. go-plus.json P2Y6 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031816 GO:0031817 biolink:MolecularActivity P2Y8 nucleotide receptor binding Binding to a P2Y8 nucleotide receptor. go-plus.json P2Y8 nucleotide receptor ligand http://purl.obolibrary.org/obo/GO_0031817 UBERON:0007842 biolink:AnatomicalEntity membrane bone Bone element that arises as a result of intramembranous ossification. go-plus.json membrane bones http://purl.obolibrary.org/obo/UBERON_0007842 CHEBI:32474 biolink:ChemicalSubstance L-gamma-glutamyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32474 UBERON:0007844 biolink:AnatomicalEntity cartilage element Skeletal element that is composed of cartilage tissue and may be permanent or transient. go-plus.json chondrogenic element|cartilaginous element|cartilage|cartilage organ http://purl.obolibrary.org/obo/UBERON_0007844 CHEBI:4208 biolink:ChemicalSubstance D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_4208 chebi_ph7_3 UBERON:0007845 biolink:AnatomicalEntity regular connective tissue Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007845 UBERON:0007846 biolink:AnatomicalEntity dense regular connective tissue Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts). go-plus.json dense regular collagenous connective tissue|typus regularis (textus connectivus collagenosus compactus)|dense regular collagenous tissue|regular dense connective tissue|dense fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0007846 CHEBI:32479 biolink:ChemicalSubstance D-alpha-glutamyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32479 CHEBI:32470 biolink:ChemicalSubstance aspartic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32470 CHEBI:32471 biolink:ChemicalSubstance aspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32471 GO:0031803 biolink:MolecularActivity type 6 metabotropic glutamate receptor binding Binding to a type 6 metabotropic glutamate receptor. go-plus.json type 6 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031803 GO:0006847 biolink:BiologicalProcess plasma membrane acetate transport The directed movement of acetate across a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0006847 GO:0006848 biolink:BiologicalProcess pyruvate transport The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006848 GO:0090180 biolink:BiologicalProcess positive regulation of thiamine biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. go-plus.json positive regulation of thiamin biosynthetic process http://purl.obolibrary.org/obo/GO_0090180 GO:0031804 biolink:MolecularActivity type 7 metabotropic glutamate receptor binding Binding to a type 7 metabotropic glutamate receptor. go-plus.json type 7 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031804 GO:0031801 biolink:MolecularActivity type 4 metabotropic glutamate receptor binding Binding to a type 4 metabotropic glutamate receptor. go-plus.json type 4 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031801 GO:0006845 biolink:BiologicalProcess obsolete mitochondrial aspartate/glutamate transport OBSOLETE. The directed movement of aspartate and glutamate into, out of or within a mitochondrion. go-plus.json mitochondrial aspartate/glutamate transport http://purl.obolibrary.org/obo/GO_0006845 GO:0031802 biolink:MolecularActivity type 5 metabotropic glutamate receptor binding Binding to a type 5 metabotropic glutamate receptor. go-plus.json type 5 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031802 GO:0006846 biolink:BiologicalProcess acetate transport The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006846 GO:0090183 biolink:BiologicalProcess regulation of kidney development Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json regulation of nephrogenesis http://purl.obolibrary.org/obo/GO_0090183 GO:0006843 biolink:BiologicalProcess mitochondrial citrate transmembrane transport The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix. go-plus.json mitochondrial citrate transport http://purl.obolibrary.org/obo/GO_0006843 GO:0031800 biolink:MolecularActivity type 3 metabotropic glutamate receptor binding Binding to a type 3 metabotropic glutamate receptor. go-plus.json type 3 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031800 GO:0006844 biolink:BiologicalProcess acyl carnitine transport The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0006844 GO:0090184 biolink:BiologicalProcess positive regulation of kidney development Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json positive regulation of nephrogenesis http://purl.obolibrary.org/obo/GO_0090184 GO:0006841 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006841 GO:0090181 biolink:BiologicalProcess regulation of cholesterol metabolic process Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0090181 GO:0090182 biolink:BiologicalProcess regulation of secretion of lysosomal enzymes Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0090182 GO:0006842 biolink:BiologicalProcess tricarboxylic acid transport The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006842 UBERON:0007827 biolink:AnatomicalEntity external nose External part of the nose containing the external nares. go-plus.json nose http://purl.obolibrary.org/obo/UBERON_0007827 CHEBI:32447 biolink:ChemicalSubstance L-cysteinyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32447 GO:0006840 biolink:BiologicalProcess obsolete mitochondrial alpha-ketoglutarate/malate transport OBSOLETE. The directed movement of alpha-ketoglutarate and malate into, out of or within a mitochondrion. go-plus.json mitochondrial oxoglutarate/malate transport|mitochondrial alpha-ketoglutarate/malate transport http://purl.obolibrary.org/obo/GO_0006840 UBERON:0007828 biolink:AnatomicalEntity girdle bone/zone A bone that is part of a appendage girdle region. go-plus.json girdle bone http://purl.obolibrary.org/obo/UBERON_0007828 CHEBI:32448 biolink:ChemicalSubstance L-cysteino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32448 UBERON:0007829 biolink:AnatomicalEntity pectoral girdle bone A bone that is part of a pectoral girdle region. go-plus.json bone of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0007829 GO:0031809 biolink:MolecularActivity H3 histamine receptor binding Binding to a H3 histamine receptor. go-plus.json H3 histamine receptor ligand http://purl.obolibrary.org/obo/GO_0031809 CHEBI:32449 biolink:ChemicalSubstance D-cysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32449 GO:0031807 biolink:MolecularActivity H1 histamine receptor binding Binding to a H1 histamine receptor. go-plus.json H1 histamine receptor ligand http://purl.obolibrary.org/obo/GO_0031807 GO:0031808 biolink:MolecularActivity H2 histamine receptor binding Binding to a H2 histamine receptor. go-plus.json H2 histamine receptor ligand http://purl.obolibrary.org/obo/GO_0031808 GO:0031805 biolink:MolecularActivity type 8 metabotropic glutamate receptor binding Binding to a type 8 metabotropic glutamate receptor. go-plus.json type 8 metabotropic glutamate receptor ligand http://purl.obolibrary.org/obo/GO_0031805 GO:0031806 biolink:MolecularActivity G protein-coupled histamine receptor binding Binding to a G protein-coupled (metabotropic) histamine receptor. go-plus.json metabotropic histamine receptor binding|metabotropic histamine receptor ligand|G-protein coupled histamine receptor binding http://purl.obolibrary.org/obo/GO_0031806 UBERON:0007830 biolink:AnatomicalEntity pelvic girdle bone/zone A bone element or fused bone that is part of pelvic girdle. go-plus.json pelvic girdle bone|bone of pelvic girdle http://purl.obolibrary.org/obo/UBERON_0007830 UBERON:0007831 biolink:AnatomicalEntity pectoral girdle skeleton A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons. go-plus.json skeletal parts of pectoral girdle|pectoral girdle|skeleton of pectoral girdle|scapular girdle|cingulum pectorale http://purl.obolibrary.org/obo/UBERON_0007831 CHEBI:32440 biolink:ChemicalSubstance alaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32440 UBERON:0007832 biolink:AnatomicalEntity pelvic girdle skeleton Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature. go-plus.json pelvic girdle skeleton|skeletal parts of pelvic girdle|pelvic girdle|skeleton of pelvic girdle http://purl.obolibrary.org/obo/UBERON_0007832 CHEBI:32442 biolink:ChemicalSubstance L-cysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32442 CHEBI:32443 biolink:ChemicalSubstance L-cysteinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32443 UBERON:0007836 biolink:AnatomicalEntity cervical spinal cord ventral commissure A spinal cord ventral commissure that is part of a cervical spinal cord. go-plus.json cervical spinal cord anterior commissure http://purl.obolibrary.org/obo/UBERON_0007836 CHEBI:32445 biolink:ChemicalSubstance L-cysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32445 PATO:0001396 biolink:OntologyClass cellular quality A monadic quality of continuant that exists at the cellular level of organisation. go-plus.json http://purl.obolibrary.org/obo/PATO_0001396 UBERON:0007837 biolink:AnatomicalEntity thoracic spinal cord ventral commissure A spinal cord ventral commissure that is part of a thoracic spinal cord. go-plus.json thoracic spinal cord anterior commissure http://purl.obolibrary.org/obo/UBERON_0007837 CHEBI:32446 biolink:ChemicalSubstance all-trans-neoxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_32446 chebi_ph7_3 GO:0090187 biolink:BiologicalProcess positive regulation of pancreatic juice secretion Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0090187 GO:0090188 biolink:BiologicalProcess negative regulation of pancreatic juice secretion Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0090188 GO:0090185 biolink:BiologicalProcess negative regulation of kidney development Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json negative regulation of nephrogenesis http://purl.obolibrary.org/obo/GO_0090185 GO:0090186 biolink:BiologicalProcess regulation of pancreatic juice secretion Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0090186 GO:0090189 biolink:BiologicalProcess regulation of branching involved in ureteric bud morphogenesis Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0090189 GO:0006849 biolink:BiologicalProcess plasma membrane pyruvate transport The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0006849 GO:0090190 biolink:BiologicalProcess positive regulation of branching involved in ureteric bud morphogenesis Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0090190 GO:0006858 biolink:BiologicalProcess extracellular transport The transport of substances that occurs outside cells. go-plus.json http://purl.obolibrary.org/obo/GO_0006858 GO:0090191 biolink:BiologicalProcess negative regulation of branching involved in ureteric bud morphogenesis Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0090191 GO:0006859 biolink:BiologicalProcess extracellular carbohydrate transport The directed extracellular movement of carbohydrates. go-plus.json http://purl.obolibrary.org/obo/GO_0006859 GO:0006856 biolink:BiologicalProcess eye pigment precursor transport The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0006856 GO:0006857 biolink:BiologicalProcess oligopeptide transport The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0006857 GO:0006854 biolink:BiologicalProcess obsolete ATP/ADP exchange OBSOLETE. (Was not defined before being made obsolete). go-plus.json ATP/ADP exchange http://purl.obolibrary.org/obo/GO_0006854 GO:0090194 biolink:BiologicalProcess negative regulation of glomerulus development Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0090194 GO:0090195 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090195 GO:0006855 biolink:BiologicalProcess xenobiotic transmembrane transport The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json drug transmembrane transport|multidrug transport|drug membrane transport http://purl.obolibrary.org/obo/GO_0006855 GO:0006852 biolink:BiologicalProcess obsolete mitochondrial sodium/calcium ion exchange OBSOLETE. (Was not defined before being made obsolete). go-plus.json mitochondrial sodium/calcium exchange|mitochondrial sodium/calcium ion exchange http://purl.obolibrary.org/obo/GO_0006852 GO:0090192 biolink:BiologicalProcess regulation of glomerulus development Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0090192 GO:0090193 biolink:BiologicalProcess positive regulation of glomerulus development Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0090193 GO:0006853 biolink:BiologicalProcess carnitine shuttle The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine. Wikipedia:Carnitine#Role_in_fatty_acid_metabolism go-plus.json http://purl.obolibrary.org/obo/GO_0006853 GO:0006850 biolink:BiologicalProcess mitochondrial pyruvate transmembrane transport The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json pyruvate transmembrane transport in mitochondrion|pyruvate membrane transport in mitochondria|pyruvate membrane transport in mitochondrion|pyruvate transmembrane transport in mitochondria|mitochondrial pyruvate transport http://purl.obolibrary.org/obo/GO_0006850 CHEBI:32458 biolink:ChemicalSubstance cysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32458 GO:0006851 biolink:BiologicalProcess mitochondrial calcium ion transmembrane transport The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json mitochondrial calcium transport http://purl.obolibrary.org/obo/GO_0006851 CHEBI:32459 biolink:ChemicalSubstance cysteino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32459 CHEBI:32450 biolink:ChemicalSubstance D-cysteinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32450 CHEBI:32451 biolink:ChemicalSubstance D-cysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32451 CHEBI:32452 biolink:ChemicalSubstance D-cysteinyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32452 CHEBI:32453 biolink:ChemicalSubstance D-cysteino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32453 UBERON:0007823 biolink:AnatomicalEntity appendage girdle region An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). go-plus.json girdle|fin girdle|girdle region|limb girdle|limb girdle region|fin girdle region http://purl.obolibrary.org/obo/UBERON_0007823 CHEBI:32456 biolink:ChemicalSubstance cysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32456 CHEBI:32457 biolink:ChemicalSubstance cysteinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32457 UBERON:0007826 biolink:AnatomicalEntity peritoneal mesentery Mesentery that is located in the peritoneum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007826 GO:0090198 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090198 GO:0090199 biolink:BiologicalProcess regulation of release of cytochrome c from mitochondria Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. go-plus.json http://purl.obolibrary.org/obo/GO_0090199 GO:0090196 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090196 GO:0090197 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0090197 CHEBI:22187 biolink:ChemicalSubstance acetophenones go-plus.json http://purl.obolibrary.org/obo/CHEBI_22187 UBERON:0003968 biolink:AnatomicalEntity peripheral lymph node The lymph nodes located outside the thoracic and abdominal cavities, such as the submandibular, prescapular, axillary, inguinal and popliteal lymph nodes go-plus.json http://purl.obolibrary.org/obo/UBERON_0003968 UBERON:0003967 biolink:AnatomicalEntity cutaneous elastic tissue The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity go-plus.json cutaneous elastic fiber|dermal elastic fiber http://purl.obolibrary.org/obo/UBERON_0003967 NCBITaxon:33090 biolink:OrganismalEntity Viridiplantae go-plus.json Chlorophyta/Embryophyta group|Chlorobionta|green plants|chlorophyte/embryophyte group|Chloroplastida|green plants http://purl.obolibrary.org/obo/NCBITaxon_33090 CHEBI:22180 biolink:ChemicalSubstance EC 2.2.1.6 (acetolactate synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_22180 CHEBI:61796 biolink:ChemicalSubstance dinoflagellate luciferin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61796 chebi_ph7_3 CHEBI:61799 biolink:ChemicalSubstance beta-D-galactopyranosyl diglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_61799 chebi_ph7_3 UBERON:0003975 biolink:AnatomicalEntity internal female genitalia The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina. go-plus.json female internal genitalia|internal female genital organ|organa genitalia feminina interna|internal genitalia of female reproductive system http://purl.obolibrary.org/obo/UBERON_0003975 UBERON:0003970 biolink:AnatomicalEntity placental labyrinth vasculature blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate go-plus.json vasculature of placenta labyrinth|placental labyrinth vascular network|placental vasculature http://purl.obolibrary.org/obo/UBERON_0003970 UBERON:0003959 biolink:AnatomicalEntity rete testis An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]. go-plus.json Haller's rete http://purl.obolibrary.org/obo/UBERON_0003959 CHEBI:22198 biolink:ChemicalSubstance acetylcysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22198 NCBITaxon:33083 biolink:OrganismalEntity Dictyostelia go-plus.json Dictyostelida|Dictyosteliida|cellular slime molds|Dictyostelids|dictyostelid cellular slime molds http://purl.obolibrary.org/obo/NCBITaxon_33083 NCBITaxon:33084 biolink:OrganismalEntity Entamoebidae go-plus.json Entamoebida http://purl.obolibrary.org/obo/NCBITaxon_33084 UBERON:0003956 biolink:AnatomicalEntity aqueous drainage system The structures associated with drainage of the aqueous humor from the eye, that include the trabecular meshwork, Schlemm's canal, the uveoscleral network, and the aqueous veins go-plus.json http://purl.obolibrary.org/obo/UBERON_0003956 CHEBI:22193 biolink:ChemicalSubstance acetyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22193 CHEBI:131845 biolink:ChemicalSubstance 2-methylpropane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_131845 chebi_ph7_3 CHEBI:22191 biolink:ChemicalSubstance acetyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_22191 chebi_ph7_3 CHEBI:131846 biolink:ChemicalSubstance 2-hydroxy-2-methylpropanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_131846 chebi_ph7_3 CHEBI:131847 biolink:ChemicalSubstance 2,4-didehydro-3-deoxy-L-rhamnonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131847 chebi_ph7_3 CHEBI:131849 biolink:ChemicalSubstance D-erythritol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131849 chebi_ph7_3 CHEBI:22194 biolink:ChemicalSubstance acetyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22194 CHEBI:46143 biolink:ChemicalSubstance UDP-N-acetyl-alpha-muramoyl-L-alanyl-D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_46143 CHEBI:22195 biolink:ChemicalSubstance acetyl-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22195 NCBITaxon:33072 biolink:OrganismalEntity Gloeobacter violaceus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33072 UBERON:0003946 biolink:AnatomicalEntity placenta labyrinth The placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood go-plus.json placental labyrinth|labyrinthine layer|labyrinthine layer of placenta http://purl.obolibrary.org/obo/UBERON_0003946 UBERON:0003947 biolink:AnatomicalEntity brain ventricle/choroid plexus The brain ventricles or their associated choroid plexuses go-plus.json http://purl.obolibrary.org/obo/UBERON_0003947 NCBITaxon:33071 biolink:OrganismalEntity Gloeobacter go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33071 CHEBI:22160 biolink:ChemicalSubstance acetamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_22160 CHEBI:85780 biolink:ChemicalSubstance N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85780 CHEBI:85783 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85783 CHEBI:85784 biolink:ChemicalSubstance N-arachidonoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85784 PR:000012826 biolink:Protein urokinase-type plasminogen activator A protein that is a translation product of the human PLAU gene or a 1:1 ortholog thereof. go-plus.json PLAU|uPA|U-plasminogen activator http://purl.obolibrary.org/obo/PR_000012826 CHEBI:85785 biolink:ChemicalSubstance monodechloroaminopyrrolnitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85785 chebi_ph7_3 CHEBI:85786 biolink:ChemicalSubstance aminopyrrolnitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85786 chebi_ph7_3 CHEBI:85787 biolink:ChemicalSubstance 1-decanoyl-2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85787 chebi_ph7_3 UBERON:0003953 biolink:AnatomicalEntity posterior stroma of cornea The posterior segment of the lamellated connective tissue layer of the cornea go-plus.json cornea posterior stroma|posterior stroma http://purl.obolibrary.org/obo/UBERON_0003953 UBERON:0003952 biolink:AnatomicalEntity anterior stroma of cornea The anterior segment of the lamellated connective tissue layer of the cornea go-plus.json anterior stroma|cornea anterior stroma http://purl.obolibrary.org/obo/UBERON_0003952 CHEBI:22179 biolink:ChemicalSubstance acetohydroximates go-plus.json http://purl.obolibrary.org/obo/CHEBI_22179 UBERON:0003937 biolink:AnatomicalEntity reproductive gland Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. go-plus.json sex gland|gland of reproductive system|genitalia gland|reproductive gland|reproductive system gland|gland of genitalia http://purl.obolibrary.org/obo/UBERON_0003937 CHEBI:22177 biolink:ChemicalSubstance acetohydroxamic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_22177 UBERON:0003935 biolink:AnatomicalEntity mesenchyme pelvic fin Mesenchyme that is part of a developing pelvic fin [Automatically generated definition]. go-plus.json mesenchyme of pelvic fin|mesenchyme pelvic fins|pelvic fin mesenchyme http://purl.obolibrary.org/obo/UBERON_0003935 UBERON:0003933 biolink:AnatomicalEntity cranial cartilage A cartilage element that is part of the cranial skeleton. go-plus.json cranium cartilage|cartilage of cranium|cranial cartilages http://purl.obolibrary.org/obo/UBERON_0003933 UBERON:0003934 biolink:AnatomicalEntity mesenchyme pectoral fin Mesenchyme that is part of a developing pectoral fin [Automatically generated definition]. go-plus.json mesenchyme pectoral fins|mesenchyme of pectoral fin|pectoral fin mesenchyme http://purl.obolibrary.org/obo/UBERON_0003934 CHEBI:131822 biolink:ChemicalSubstance sulfamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131822 chebi_ph7_3 CHEBI:131823 biolink:ChemicalSubstance methylated primary amine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131823 chebi_ph7_3 CHEBI:85777 biolink:ChemicalSubstance Cer(d42:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85777 chebi_ph7_3 CHEBI:85778 biolink:ChemicalSubstance 4beta-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85778 chebi_ph7_3 CHEBI:85779 biolink:ChemicalSubstance 4beta,7alpha-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85779 chebi_ph7_3 UBERON:0003942 biolink:AnatomicalEntity somatic sensory system The sensory system for the sense of touch and pain. go-plus.json somatosensory system|somatic sensory system|system for detection of somatic senses http://purl.obolibrary.org/obo/UBERON_0003942 CHEBI:71156 biolink:ChemicalSubstance N-acyl-15-methylhexadecasphing-4-enine-1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71156 chebi_ph7_3 CHEBI:22144 biolink:ChemicalSubstance abscisic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_22144 chebi_ph7_3 CHEBI:36786 biolink:ChemicalSubstance tetralins go-plus.json http://purl.obolibrary.org/obo/CHEBI_36786 CHEBI:36785 biolink:ChemicalSubstance carbobicyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36785 CHEBI:36782 biolink:ChemicalSubstance tetraterpenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36782 CHEBI:36783 biolink:ChemicalSubstance apo carotenoid triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36783 CHEBI:36780 biolink:ChemicalSubstance triterpenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36780 CHEBI:36781 biolink:ChemicalSubstance 1-pyrrolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_36781 chebi_ph7_3 CHEBI:22156 biolink:ChemicalSubstance acenaphthenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_22156 CHEBI:22154 biolink:ChemicalSubstance acenaphthene go-plus.json http://purl.obolibrary.org/obo/CHEBI_22154 chebi_ph7_3 CHEBI:85790 biolink:ChemicalSubstance N,1,2-trioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85790 CHEBI:85791 biolink:ChemicalSubstance N-stearoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85791 CHEBI:131803 biolink:ChemicalSubstance L-allysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_131803 chebi_ph7_3 CHEBI:85793 biolink:ChemicalSubstance N-myristoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85793 CHEBI:22152 biolink:ChemicalSubstance 2-cis-abscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22152 CHEBI:22153 biolink:ChemicalSubstance acaricide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22153 CHEBI:85794 biolink:ChemicalSubstance N-lauroyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85794 CHEBI:22151 biolink:ChemicalSubstance (+)-abscisic acid beta-D-glucopyranosyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_22151 chebi_ph7_3 CHEBI:85796 biolink:ChemicalSubstance N-capryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85796 CHEBI:85797 biolink:ChemicalSubstance N-capryloyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85797 CHEBI:85798 biolink:ChemicalSubstance N-caproyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85798 CHEBI:85799 biolink:ChemicalSubstance N-butyryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85799 CHEBI:71163 biolink:ChemicalSubstance 2,3-didehydroadipoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71163 CHEBI:71164 biolink:ChemicalSubstance (R)-lactoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71164 CHEBI:71165 biolink:ChemicalSubstance N-acyl-15-methylhexadecasphing-4-enine-1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71165 UBERON:0003988 biolink:AnatomicalEntity thymus corticomedullary boundary The dense region demarcating the thymus medulla from the surrounding cortex that is characterized by numerous blood vessels (predominantly arterioles) with some perivascular connective tissue, mature and immature T lymphocytes, dendritic cells, variable numbers of perivascular B-lymphocytes and plasma cells; site of entry of bone marrow stem cells and exit of mature, functional T cells go-plus.json thymic corticomedullary junction|thymus corticomedullary zone|thymus CMZ|thymic corticomedullary zone|thymic corticomedullary boundary|thymic cortico-medullary boundary|thymus cortico-medullary boundary|thymus corticomedullary junction http://purl.obolibrary.org/obo/UBERON_0003988 CHEBI:36765 biolink:ChemicalSubstance gibberellane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36765 CHEBI:36762 biolink:ChemicalSubstance abietane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36762 CHEBI:36768 biolink:ChemicalSubstance casbane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36768 CHEBI:36766 biolink:ChemicalSubstance ent-gibberellane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36766 CHEBI:36760 biolink:ChemicalSubstance ent-kaurane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36760 CHEBI:71175 biolink:ChemicalSubstance 7,8-dihydromonapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71175 chebi_ph7_3 CHEBI:36761 biolink:ChemicalSubstance 1-pyrroline-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36761 CHEBI:71177 biolink:ChemicalSubstance tetrahydromonapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71177 chebi_ph7_3 CHEBI:71189 biolink:ChemicalSubstance iminodiacetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_71189 chebi_ph7_3 UBERON:0003978 biolink:AnatomicalEntity valve go-plus.json anatomical valve http://purl.obolibrary.org/obo/UBERON_0003978 CHEBI:36775 biolink:ChemicalSubstance bornane-2,5-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_36775 chebi_ph7_3 CHEBI:36776 biolink:ChemicalSubstance (1S)-bornane-2,5-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_36776 chebi_ph7_3 CHEBI:36773 biolink:ChemicalSubstance camphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_36773 chebi_ph7_3 CHEBI:71181 biolink:ChemicalSubstance Sir2 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_71181 UBERON:0003984 biolink:AnatomicalEntity uterine tube infundibulum The funnel-like expansion of the abdominal extremity of the uterine tube[MP] go-plus.json infundibulum tubae uterinae|infundibulum of uterine tube|infundibulum of fallopian tube|infundibulum of oviduct|infundibulum http://purl.obolibrary.org/obo/UBERON_0003984 CHEBI:71185 biolink:ChemicalSubstance methyl 3-cyano-2-phenylpropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71185 chebi_ph7_3 UBERON:0003983 biolink:AnatomicalEntity conus arteriosus A conical pouch formed from the upper and left angle of the right ventricle in the chordate heart, from which the pulmonary artery arises[WP]. the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminates in the pulmonary trunk[MP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003983 CHEBI:36772 biolink:ChemicalSubstance diterpenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36772 UBERON:0003980 biolink:AnatomicalEntity cerebellum fissure One of a set of deep furrows which divide the lobules of the cerebellum. Examples: postcentral, primary and secondary furrows go-plus.json fissurae cerebelli|set of cerebellar fissures|cerebellar sulci|cerebellar fissure|sulcus of cerebellum|cerebellar sulcus|cerebellar fissures set|cerebellar fissures http://purl.obolibrary.org/obo/UBERON_0003980 CHEBI:71187 biolink:ChemicalSubstance 3beta-hydroxy-4alpha-carboxysteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71187 UBERON:0003981 biolink:AnatomicalEntity primordial ovarian follicle primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles go-plus.json ovary primordial follicle|primordial follicle http://purl.obolibrary.org/obo/UBERON_0003981 CHEBI:36770 biolink:ChemicalSubstance labdane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36770 CHEBI:71188 biolink:ChemicalSubstance 3-oxocyclopentanecarbonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_71188 chebi_ph7_3 GO:0035548 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035548 GO:0035549 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035549 GO:0035540 biolink:BiologicalProcess positive regulation of SNARE complex disassembly Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035540 GO:0035541 biolink:BiologicalProcess negative regulation of SNARE complex disassembly Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035541 GO:0035542 biolink:BiologicalProcess regulation of SNARE complex assembly Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035542 GO:0035543 biolink:BiologicalProcess positive regulation of SNARE complex assembly Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035543 GO:0035544 biolink:BiologicalProcess negative regulation of SNARE complex assembly Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035544 GO:0035545 biolink:BiologicalProcess determination of left/right asymmetry in nervous system The establishment of the nervous system with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0035545 GO:0035546 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035546 CHEBI:141249 biolink:ChemicalSubstance N-carbamoyl-D-phenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_141249 GO:0035547 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035547 CHEBI:61717 biolink:ChemicalSubstance ferroheme c(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61717 chebi_ph7_3 GO:0035537 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035537 GO:0035538 biolink:MolecularActivity carbohydrate response element binding Binding to a carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes. go-plus.json ChoRE binding http://purl.obolibrary.org/obo/GO_0035538 GO:0035539 biolink:MolecularActivity 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA. Reactome:R-HSA-2395849|Reactome:R-HSA-2395869|RHEA:31575|EC:3.6.1.55 go-plus.json 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase activity|8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity|8-oxo-dGTPase activity|8-oxo-7,8-dihydro-deoxyguanosine triphosphate pyrophosphatase activity|8-oxo-dGTP pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0035539 CHEBI:61720 biolink:ChemicalSubstance bacteriochlorophyll a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61720 chebi_ph7_3 GO:0035530 biolink:BiologicalProcess chemokine (C-C motif) ligand 6 production The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CCL6 production http://purl.obolibrary.org/obo/GO_0035530 gocheck_do_not_annotate CHEBI:61721 biolink:ChemicalSubstance chlorophyll b(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61721 chebi_ph7_3 GO:0035531 biolink:BiologicalProcess regulation of chemokine (C-C motif) ligand 6 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6). go-plus.json regulation of chemokine (C-C motif) ligand 6 secretion|chemokine (C-C motif) ligand 6 secretion|regulation of CCL6 production http://purl.obolibrary.org/obo/GO_0035531 GO:0035532 biolink:BiologicalProcess negative regulation of chemokine (C-C motif) ligand 6 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6). go-plus.json negative regulation of CCL6 production|negative regulation of chemokine (C-C motif) ligand 6 secretion http://purl.obolibrary.org/obo/GO_0035532 GO:0035533 biolink:BiologicalProcess positive regulation of chemokine (C-C motif) ligand 6 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6). go-plus.json positive regulation of chemokine (C-C motif) ligand 6 secretion|positive regulation of CCL6 production http://purl.obolibrary.org/obo/GO_0035533 GO:0035534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035534 CHEBI:61725 biolink:ChemicalSubstance oct-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_61725 chebi_ph7_3 GO:0035535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035535 CHEBI:61723 biolink:ChemicalSubstance D-pantetheine 4'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61723 chebi_ph7_3 GO:0035536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035536 CHEBI:61727 biolink:ChemicalSubstance dec-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_61727 chebi_ph7_3 GO:0035526 biolink:BiologicalProcess retrograde transport, plasma membrane to Golgi The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0035526 GO:0035527 biolink:MolecularActivity 3-hydroxypropionate dehydrogenase (NADP+) activity Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH. RHEA:26438|KEGG_REACTION:R09289|EC:1.1.1.298|MetaCyc:RXN-8974 go-plus.json 3-hydroxypropanoate dehydrogenase (NADP+) activity|3-hydroxypropionate:NADP+ oxidoreductase|3-hydroxypropanoate:NADP+ oxidoreductase http://purl.obolibrary.org/obo/GO_0035527 GO:0035528 biolink:BiologicalProcess obsolete UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin. go-plus.json UDP-GlcNAc biosynthetic process involved in chitin biosynthetic process|UDP-GlcNAc biosynthesis involved in chitin biosynthesis|UDP-GlcNAc biosynthetic process involved in chitin biosynthesis|UDP-N-acetylglucosamine anabolism involved in chitin biosynthesis|UDP-N-acetylglucosamine synthesis involved in chitin biosynthesis|UDP-N-acetylglucosamine formation involved in chitin biosynthesis|UDP-N-acetylglucosamine biosynthetic process involved in chitin biosynthetic process http://purl.obolibrary.org/obo/GO_0035528 GO:0035529 biolink:MolecularActivity NADH pyrophosphatase activity Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+. KEGG_REACTION:R00103|EC:3.6.1.9|Reactome:R-HSA-6809287|MetaCyc:RXN0-4401 go-plus.json NADH diphosphatase activity|NADH pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0035529 CHEBI:61732 biolink:ChemicalSubstance beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61732 GO:0035520 biolink:BiologicalProcess monoubiquitinated protein deubiquitination The removal of the ubiquitin group from a monoubiquitinated protein. go-plus.json monoubiquitinated protein deubiquitylation|monoubiquitinated protein deubiquitinylation http://purl.obolibrary.org/obo/GO_0035520 GO:0035521 biolink:BiologicalProcess monoubiquitinated histone deubiquitination The removal of the ubiquitin group from a monoubiquitinated histone protein. go-plus.json monoubiquitinated histone deubiquitylation|monoubiquitinated histone deubiquitinylation http://purl.obolibrary.org/obo/GO_0035521 CHEBI:85701 biolink:ChemicalSubstance diacylglycerol 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85701 chebi_ph7_3 GO:0035522 biolink:BiologicalProcess monoubiquitinated histone H2A deubiquitination The removal of the ubiquitin group from a monoubiquitinated histone H2A protein. go-plus.json monoubiquitinated histone H2A deubiquitylation|monoubiquitinated histone H2A deubiquitinylation http://purl.obolibrary.org/obo/GO_0035522 CHEBI:131894 biolink:ChemicalSubstance N-arachidonoylethanolamine phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131894 chebi_ph7_3 CHEBI:61735 biolink:ChemicalSubstance lipid IIA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61735 GO:0035523 biolink:BiologicalProcess protein K29-linked deubiquitination A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein. go-plus.json protein K29-linked deubiquitylation|protein K29-linked deubiquitinylation http://purl.obolibrary.org/obo/GO_0035523 CHEBI:61736 biolink:ChemicalSubstance thujopsene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61736 GO:0035524 biolink:BiologicalProcess proline transmembrane transport The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore. go-plus.json proline membrane transport http://purl.obolibrary.org/obo/GO_0035524 GO:0035525 biolink:CellularComponent NF-kappaB p50/p65 complex A heterodimer of NF-kappa B p50 and p65 subunits. go-plus.json NF-kappa p105/RelA complex|NF-kappa B1/RelA complex|NF-kappa B1/p65 complex|NF-kappa p50/RelA complex|NF-kappa p105/p65 complex http://purl.obolibrary.org/obo/GO_0035525 CHEBI:61734 biolink:ChemicalSubstance lipid IIA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61734 CHEBI:61737 biolink:ChemicalSubstance (+)-thujopsene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61737 chebi_ph7_3 GO:0035515 biolink:MolecularActivity oxidative RNA demethylase activity Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. Reactome:R-HSA-8857692 go-plus.json 2-oxoglutarate-dependent RNA demethylase http://purl.obolibrary.org/obo/GO_0035515 GO:0035516 biolink:MolecularActivity oxidative DNA demethylase activity Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O(2) = a nucleobase within DNA + formaldehyde + succinate + CO(2). EC:1.14.11.33|RHEA:30299|MetaCyc:RXN0-986|MetaCyc:RXN0-985|MetaCyc:RXN0-984 go-plus.json 1-ethyladenine demethylase activity|N3-methylcytosine demethylase activity|N1-methyladenine demethylase activity|2-oxoglutarate-dependent DNA demethylase http://purl.obolibrary.org/obo/GO_0035516 CHEBI:141211 biolink:ChemicalSubstance (R)-3-hydroxyisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_141211 chebi_ph7_3 GO:0035517 biolink:CellularComponent PR-DUB complex A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively. go-plus.json Polycomb repressive deubiquitinase complex http://purl.obolibrary.org/obo/GO_0035517 CHEBI:141212 biolink:ChemicalSubstance (R)-methylmalonate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_141212 chebi_ph7_3 GO:0035518 biolink:BiologicalProcess histone H2A monoubiquitination The modification of histone H2A by addition of a single ubiquitin group. go-plus.json http://purl.obolibrary.org/obo/GO_0035518 GO:0035519 biolink:BiologicalProcess protein K29-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation. go-plus.json protein K29-linked polyubiquitination http://purl.obolibrary.org/obo/GO_0035519 CHEBI:141219 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 32:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141219 GO:0035510 biolink:BiologicalProcess DNA dealkylation The removal of an alkyl group from one or more nucleotides within an DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035510 GO:0035511 biolink:BiologicalProcess oxidative DNA demethylation Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. go-plus.json http://purl.obolibrary.org/obo/GO_0035511 CHEBI:61746 biolink:ChemicalSubstance (+)-beta-chamigrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61746 chebi_ph7_3 GO:0035512 biolink:BiologicalProcess hydrolytic DNA demethylation The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035512 GO:0035513 biolink:BiologicalProcess oxidative RNA demethylation The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms. go-plus.json http://purl.obolibrary.org/obo/GO_0035513 CHEBI:61744 biolink:ChemicalSubstance beta-chamigrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61744 chebi_ph7_3 GO:0035514 biolink:MolecularActivity DNA demethylase activity Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035514 CHEBI:61748 biolink:ChemicalSubstance (E)-oct-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_61748 chebi_ph7_3 UBERON:0003928 biolink:AnatomicalEntity digestive system duct A duct that is part of a digestive system [Automatically generated definition]. go-plus.json duct of digestive system|duct of gastrointestinal system|gastrointestinal system duct http://purl.obolibrary.org/obo/UBERON_0003928 UBERON:0003929 biolink:AnatomicalEntity digestive tract epithelium An epithelium that lines the lumen of the digestive tract. go-plus.json alimentary tract epithelium|gut epithelium|gastrodermis|epithelium of digestive tract|epithelial tissue of digestive tract|epithelium of gut|epithelial tissue of gut|digestive tract epithelial tissue|gut epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003929 UBERON:0003924 biolink:AnatomicalEntity ventral pancreatic bud pancreatic bud that gives rise to the major pancreatic duct. go-plus.json pancreas ventral primordium duct bud|ventral pancreatic anlage|anterior pancreatic bud|ventral pancreas anlage|pancreas primordium ventral bud|anterior pancreatic anlage http://purl.obolibrary.org/obo/UBERON_0003924 UBERON:0003922 biolink:AnatomicalEntity pancreatic epithelial bud The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. go-plus.json pancreatic buds|pancreas epithelium|pancreatic bud|pancreatic anlage http://purl.obolibrary.org/obo/UBERON_0003922 UBERON:0003923 biolink:AnatomicalEntity dorsal pancreatic bud pancreatic bud that gives rise to the accessory pancreatic duct. go-plus.json dorsal pancreas anlage|pancreas dorsal primordium duct bud|primary pancreatic bud|posterior pancreatic anlage|posterior pancreatic bud|pancreas primordium dorsal bud|dorsal pancreatic anlage http://purl.obolibrary.org/obo/UBERON_0003923 GO:0035504 biolink:BiologicalProcess regulation of myosin light chain kinase activity Any process that modulates the frequency, rate or extent of myosin light chain kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035504 CHEBI:131876 biolink:ChemicalSubstance hydroperoxyicosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131876 GO:0035505 biolink:BiologicalProcess positive regulation of myosin light chain kinase activity Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035505 CHEBI:131877 biolink:ChemicalSubstance dihydroxyicosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131877 GO:0035506 biolink:BiologicalProcess negative regulation of myosin light chain kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035506 CHEBI:131878 biolink:ChemicalSubstance cholanic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131878 CHEBI:46195 biolink:ChemicalSubstance paracetamol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46195 chebi_ph7_3 GO:0035507 biolink:BiologicalProcess regulation of myosin-light-chain-phosphatase activity Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035507 CHEBI:131879 biolink:ChemicalSubstance cholanic acid conjugate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131879 GO:0035508 biolink:BiologicalProcess positive regulation of myosin-light-chain-phosphatase activity Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035508 GO:0035509 biolink:BiologicalProcess negative regulation of myosin-light-chain-phosphatase activity Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035509 CHEBI:85721 biolink:ChemicalSubstance diacylglycerol 28:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85721 chebi_ph7_3 CHEBI:131870 biolink:ChemicalSubstance hydroxy monounsaturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131870 CHEBI:131871 biolink:ChemicalSubstance hydroxy polyunsaturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131871 chebi_ph7_3 GO:0035500 biolink:MolecularActivity MH2 domain binding Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers. go-plus.json MAD homology 2 domain binding http://purl.obolibrary.org/obo/GO_0035500 CHEBI:131872 biolink:ChemicalSubstance hydroxy saturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131872 GO:0035501 biolink:MolecularActivity MH1 domain binding Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors. go-plus.json MAD homology 1 domain binding http://purl.obolibrary.org/obo/GO_0035501 CHEBI:131873 biolink:ChemicalSubstance EpETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131873 GO:0035502 biolink:BiologicalProcess metanephric part of ureteric bud development The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0035502 CHEBI:131874 biolink:ChemicalSubstance HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131874 CHEBI:131875 biolink:ChemicalSubstance hydroperoxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131875 GO:0035503 biolink:BiologicalProcess ureter part of ureteric bud development The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter. go-plus.json http://purl.obolibrary.org/obo/GO_0035503 UBERON:0003931 biolink:AnatomicalEntity diencephalic white matter White matter that is part of a diencephalon [Automatically generated definition]. go-plus.json white matter of diencephalon|diencephalic tracts and commissures|predominantly white regional part of diencephalon|diencephalic tract/commissure http://purl.obolibrary.org/obo/UBERON_0003931 UBERON:0003932 biolink:AnatomicalEntity cartilage element of chondrocranium A cartilage element of chondrocranium. Example: neurocranial trabecula. go-plus.json cartilage of chondrocranium|cartilaginous element of chondrocranium|neurocranium cartilage|chondrocranium cartilage http://purl.obolibrary.org/obo/UBERON_0003932 UBERON:0003930 biolink:AnatomicalEntity atrioventricular canal endocardium Endocardium that is part of the atrioventricular canal[ZFA,vetted]. go-plus.json AV canal endocardium|AVC endocardium|endocardium of atrioventricular canal|endocardium of AV canal http://purl.obolibrary.org/obo/UBERON_0003930 UBERON:0003917 biolink:AnatomicalEntity arthropod fat body An insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism. go-plus.json fat body|fat body sensu invertebrata http://purl.obolibrary.org/obo/UBERON_0003917 UBERON:0003918 biolink:AnatomicalEntity kidney mesenchyme Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]. go-plus.json mesenchyme of kidney http://purl.obolibrary.org/obo/UBERON_0003918 UBERON:0003915 biolink:AnatomicalEntity endothelial tube Any endothelium that has the quality of being cylindrical [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003915 UBERON:0003916 biolink:AnatomicalEntity fat pad A mass of closely packed fat cells (adipose tissue) surrounded by fibrous tissue septa[TMD]. go-plus.json fat body http://purl.obolibrary.org/obo/UBERON_0003916 UBERON:0003913 biolink:AnatomicalEntity tooth-like structure hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. go-plus.json tooth-like organ http://purl.obolibrary.org/obo/UBERON_0003913 CHEBI:155837 biolink:ChemicalSubstance tripeptide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_155837 chebi_ph7_3 UBERON:0003914 biolink:AnatomicalEntity epithelial tube Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. go-plus.json epithelial or endothelial tube http://purl.obolibrary.org/obo/UBERON_0003914 UBERON:0003911 biolink:AnatomicalEntity choroid plexus epithelium The epithelial component of the choroid plexus. Consists of cuboidal epithelial cells surrounding a core of capillaries and loose connective tissue. go-plus.json choroid plexus epithelial tissue|epithelial tissue of choroid plexus|epithelium of choroid plexus|epithelial tissue of chorioid plexus of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0003911 CHEBI:155834 biolink:ChemicalSubstance phosphatidylethanolamine 34:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_155834 UBERON:0003912 biolink:AnatomicalEntity chitinous tooth tooth-like structure composed of chitin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003912 CHEBI:155835 biolink:ChemicalSubstance phosphatidylethanolamine 34:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_155835 CHEBI:131889 biolink:ChemicalSubstance 11-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_131889 CHEBI:61760 biolink:ChemicalSubstance D-mannosyl ditrans,polycis-undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61760 CHEBI:61761 biolink:ChemicalSubstance D-mannosyl ditrans,polycis-undecaprenyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61761 chebi_ph7_3 UBERON:0003920 biolink:AnatomicalEntity venous blood vessel A blood vessel that carries blood from the capillaries toward the heart go-plus.json segment of venous tree organ|venous tree organ segment http://purl.obolibrary.org/obo/UBERON_0003920 UBERON:0003921 biolink:AnatomicalEntity pancreas primordium embryonic structure that develops into pancreatic bud. go-plus.json pancreatic endoderm|pancreatic primordium|pancreatic anlage|primordial pancreas http://purl.obolibrary.org/obo/UBERON_0003921 UBERON:0003906 biolink:AnatomicalEntity cardiac jelly Portion of extracellular matrix between the myocardium and the endocardium. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates. go-plus.json heart cardiac jelly http://purl.obolibrary.org/obo/UBERON_0003906 UBERON:0003907 biolink:AnatomicalEntity left atrioventricular canal An atrioventricular canal that is in the left side of a atrioventricular region. go-plus.json left atrio-ventricular canal|left AVC http://purl.obolibrary.org/obo/UBERON_0003907 UBERON:0003902 biolink:AnatomicalEntity retinal neural layer The part of the retina that contains neurons and photoreceptor cells[GO]. go-plus.json stratum nervosum (retina)|stratum nervosum retinae|neural retina|neuroretina|neural retinal epithelium|neural layer of retina http://purl.obolibrary.org/obo/UBERON_0003902 UBERON:0003903 biolink:AnatomicalEntity bursa of Fabricius An epithelial and lymphoid organ that develops as a dorsal diverticulum of the proctodeal region of the cloaca in birds. The luminal (interior) surface of the bursa is plicated with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds of bursal follicles containing follicle-associated epithelial cells, lymphocytes, macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics of mature, immunocompetent B cells[WP]. The bursa is an organ found in birds involved in B cell differentiation[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003903 CHEBI:131856 biolink:ChemicalSubstance 3,5-dimethylorsellinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131856 chebi_ph7_3 CHEBI:131857 biolink:ChemicalSubstance (3R)-farnesyl-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131857 chebi_ph7_3 CHEBI:131858 biolink:ChemicalSubstance HETE anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131858 CHEBI:131859 biolink:ChemicalSubstance oxo-ETE anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131859 chebi_ph7_3 UBERON:0003908 biolink:AnatomicalEntity right atrioventricular canal An atrioventricular canal that is in the right side of a atrioventricular region. go-plus.json right atrio-ventricular canal|right AVC http://purl.obolibrary.org/obo/UBERON_0003908 UBERON:0003909 biolink:AnatomicalEntity sinusoid small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]. go-plus.json sinusoidal blood vessel endothelium|sinusoidal endothelium|sinusoidal capillary|sinusoidal blood vessel|endothelium of irregular blood filled space http://purl.obolibrary.org/obo/UBERON_0003909 CHEBI:61777 biolink:ChemicalSubstance terpene glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_61777 CHEBI:61778 biolink:ChemicalSubstance triterpenoid saponin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61778 CHEBI:131865 biolink:ChemicalSubstance EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131865 CHEBI:131867 biolink:ChemicalSubstance hydroxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131867 CHEBI:131868 biolink:ChemicalSubstance HPDHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131868 CHEBI:131869 biolink:ChemicalSubstance hydroxy monounsaturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131869 CHEBI:131860 biolink:ChemicalSubstance octadecanoid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131860 CHEBI:131861 biolink:ChemicalSubstance HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131861 CHEBI:131862 biolink:ChemicalSubstance HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131862 CHEBI:131863 biolink:ChemicalSubstance docosanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131863 CHEBI:131864 biolink:ChemicalSubstance docosanoid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131864 GO:1901569 biolink:BiologicalProcess fatty acid derivative catabolic process The chemical reactions and pathways resulting in the breakdown of fatty acid derivative. go-plus.json fatty acid derivative breakdown|fatty acid derivative catabolism|fatty acid derivative degradation http://purl.obolibrary.org/obo/GO_1901569 GO:1901567 biolink:MolecularActivity fatty acid derivative binding Binding to fatty acid derivative. go-plus.json http://purl.obolibrary.org/obo/GO_1901567 GO:1901568 biolink:BiologicalProcess fatty acid derivative metabolic process The chemical reactions and pathways involving fatty acid derivative. go-plus.json fatty acid derivative metabolism http://purl.obolibrary.org/obo/GO_1901568 GO:1901565 biolink:BiologicalProcess organonitrogen compound catabolic process The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. go-plus.json organonitrogen compound catabolism|organonitrogen compound degradation|organonitrogen compound breakdown http://purl.obolibrary.org/obo/GO_1901565 GO:1901566 biolink:BiologicalProcess organonitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organonitrogen compound. go-plus.json organonitrogen compound anabolism|organonitrogen compound synthesis|organonitrogen compound formation|organonitrogen compound biosynthesis http://purl.obolibrary.org/obo/GO_1901566 GO:0060470 biolink:BiologicalProcess positive regulation of cytosolic calcium ion concentration involved in egg activation The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg. go-plus.json elevation of cytosolic calcium ion concentration involved in egg activation http://purl.obolibrary.org/obo/GO_0060470 GO:1901563 biolink:BiologicalProcess response to camptothecin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus. go-plus.json response to CPT http://purl.obolibrary.org/obo/GO_1901563 GO:0060471 biolink:BiologicalProcess cortical granule exocytosis The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy. go-plus.json cortical reaction|cortical granule release http://purl.obolibrary.org/obo/GO_0060471 GO:1901564 biolink:BiologicalProcess organonitrogen compound metabolic process The chemical reactions and pathways involving organonitrogen compound. go-plus.json organonitrogen compound metabolism http://purl.obolibrary.org/obo/GO_1901564 GO:1901561 biolink:BiologicalProcess response to benomyl Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901561 GO:0060472 biolink:BiologicalProcess positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol. go-plus.json positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration http://purl.obolibrary.org/obo/GO_0060472 GO:1901562 biolink:BiologicalProcess response to paraquat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901562 GO:0060473 biolink:CellularComponent cortical granule A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy. go-plus.json cortical vesicle http://purl.obolibrary.org/obo/GO_0060473 GO:0060474 biolink:BiologicalProcess positive regulation of flagellated sperm motility involved in capacitation The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence. go-plus.json positive regulation of sperm motility involved in capacitation http://purl.obolibrary.org/obo/GO_0060474 GO:1901570 biolink:BiologicalProcess fatty acid derivative biosynthetic process The chemical reactions and pathways resulting in the formation of fatty acid derivative. go-plus.json fatty acid derivative biosynthesis|fatty acid derivative anabolism|fatty acid derivative synthesis|fatty acid derivative formation http://purl.obolibrary.org/obo/GO_1901570 GO:0060475 biolink:BiologicalProcess positive regulation of actin filament polymerization involved in acrosome reaction Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction. go-plus.json positive regulation of actin polymerization involved in acrosome reaction http://purl.obolibrary.org/obo/GO_0060475 GO:1901571 biolink:BiologicalProcess fatty acid derivative transport The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901571 GO:0060476 biolink:BiologicalProcess protein localization involved in acrosome reaction The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction. go-plus.json protein localisation involved in acrosome reaction http://purl.obolibrary.org/obo/GO_0060476 GO:0060477 biolink:BiologicalProcess obsolete peptidyl-serine phosphorylation involved in acrosome reaction OBSOLETE. The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0060477 GO:0060478 biolink:BiologicalProcess acrosomal vesicle exocytosis The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction. go-plus.json acrosome exocytosis|acrosomal granule exocytosis http://purl.obolibrary.org/obo/GO_0060478 GO:0060479 biolink:BiologicalProcess lung cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json pulmonary cell differentiation http://purl.obolibrary.org/obo/GO_0060479 GO:1901578 biolink:BiologicalProcess negative regulation of alkane biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process. go-plus.json inhibition of alkane anabolism|down regulation of alkane formation|inhibition of alkane synthesis|negative regulation of alkane biosynthesis|down-regulation of alkane biosynthetic process|down-regulation of alkane biosynthesis|inhibition of alkane formation|inhibition of alkane biosynthetic process|down-regulation of alkane anabolism|negative regulation of alkane anabolism|down-regulation of alkane synthesis|inhibition of alkane biosynthesis|negative regulation of alkane synthesis|down-regulation of alkane formation|negative regulation of alkane formation|downregulation of alkane anabolism|down regulation of alkane biosynthetic process|down regulation of alkane biosynthesis|down regulation of alkane anabolism|downregulation of alkane synthesis|downregulation of alkane biosynthesis|downregulation of alkane biosynthetic process|downregulation of alkane formation|down regulation of alkane synthesis http://purl.obolibrary.org/obo/GO_1901578 GO:1901579 biolink:BiologicalProcess positive regulation of alkane biosynthetic process Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process. go-plus.json upregulation of alkane synthesis|positive regulation of alkane biosynthesis|activation of alkane biosynthetic process|upregulation of alkane formation|up-regulation of alkane anabolism|activation of alkane biosynthesis|up-regulation of alkane synthesis|up-regulation of alkane biosynthesis|up-regulation of alkane biosynthetic process|activation of alkane anabolism|up-regulation of alkane formation|activation of alkane synthesis|positive regulation of alkane anabolism|up regulation of alkane anabolism|activation of alkane formation|upregulation of alkane biosynthesis|positive regulation of alkane synthesis|upregulation of alkane biosynthetic process|up regulation of alkane synthesis|positive regulation of alkane formation|up regulation of alkane formation|upregulation of alkane anabolism|up regulation of alkane biosynthesis|up regulation of alkane biosynthetic process http://purl.obolibrary.org/obo/GO_1901579 GO:1901576 biolink:BiologicalProcess organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. go-plus.json organic molecular entity formation|organic molecular entity biosynthetic process|organic molecular entity biosynthesis|organic substance anabolism|organic substance biosynthesis|organic molecular entity anabolism|organic substance synthesis|organic molecular entity synthesis|organic substance formation http://purl.obolibrary.org/obo/GO_1901576 GO:1901577 biolink:BiologicalProcess regulation of alkane biosynthetic process Any process that modulates the frequency, rate or extent of alkane biosynthetic process. go-plus.json regulation of alkane anabolism|regulation of alkane biosynthesis|regulation of alkane synthesis|regulation of alkane formation http://purl.obolibrary.org/obo/GO_1901577 GO:1901574 biolink:BiologicalProcess obsolete chemical substance biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of chemical substance. go-plus.json chemical substance biosynthetic process|chemical substance synthesis|chemical substance formation|chemical substance biosynthesis|chemical substance anabolism http://purl.obolibrary.org/obo/GO_1901574 GO:0060460 biolink:BiologicalProcess left lung morphogenesis The process in which anatomical structures of the left lung are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060460 GO:1901575 biolink:BiologicalProcess organic substance catabolic process The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon. go-plus.json organic molecular entity catabolic process|organic substance degradation|organic molecular entity degradation|organic substance breakdown|organic molecular entity breakdown|organic molecular entity catabolism|organic substance catabolism http://purl.obolibrary.org/obo/GO_1901575 GO:1901572 biolink:BiologicalProcess obsolete chemical substance metabolic process OBSOLETE. The chemical reactions and pathways involving chemical substance. go-plus.json chemical substance metabolic process|chemical substance metabolism http://purl.obolibrary.org/obo/GO_1901572 GO:0060461 biolink:BiologicalProcess right lung morphogenesis The process in which anatomical structures of the right lung are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060461 GO:1901573 biolink:BiologicalProcess obsolete chemical substance catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of chemical substance. go-plus.json chemical substance catabolic process|chemical substance catabolism|chemical substance degradation|chemical substance breakdown http://purl.obolibrary.org/obo/GO_1901573 GO:0060462 biolink:BiologicalProcess lung lobe development The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. go-plus.json http://purl.obolibrary.org/obo/GO_0060462 GO:0060463 biolink:BiologicalProcess lung lobe morphogenesis The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. go-plus.json http://purl.obolibrary.org/obo/GO_0060463 GO:1901581 biolink:BiologicalProcess negative regulation of telomeric RNA transcription from RNA pol II promoter Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. go-plus.json down regulation of telomeric RNA transcription from Pol II promoter|inhibition of telomeric RNA transcription from Pol II promoter|down-regulation of telomeric RNA transcription from RNA pol II promoter|down-regulation of telomeric RNA transcription from Pol II promoter|negative regulation of telomeric RNA transcription from Pol II promoter|downregulation of telomeric RNA transcription from RNA pol II promoter|down regulation of telomeric RNA transcription from RNA pol II promoter|downregulation of telomeric RNA transcription from Pol II promoter|inhibition of telomeric RNA transcription from RNA pol II promoter http://purl.obolibrary.org/obo/GO_1901581 GO:0035496 biolink:MolecularActivity lipopolysaccharide-1,5-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide. go-plus.json UDP-D-galactose:(glucosyl)lipopolysaccharide-1,5-D-galactosyltransferase|LPS-1,5-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0035496 GO:0035497 biolink:MolecularActivity cAMP response element binding Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP. go-plus.json cyclic AMP response element binding|cyclic-AMP-responsive element binding|CRE binding|cAMP-responsive element binding|cyclic-AMP response element binding http://purl.obolibrary.org/obo/GO_0035497 GO:1901582 biolink:BiologicalProcess positive regulation of telomeric RNA transcription from RNA pol II promoter Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. go-plus.json upregulation of telomeric RNA transcription from RNA pol II promoter|upregulation of telomeric RNA transcription from Pol II promoter|up-regulation of telomeric RNA transcription from RNA pol II promoter|activation of telomeric RNA transcription from RNA pol II promoter|up-regulation of telomeric RNA transcription from Pol II promoter|activation of telomeric RNA transcription from Pol II promoter|up regulation of telomeric RNA transcription from RNA pol II promoter|positive regulation of telomeric RNA transcription from Pol II promoter|up regulation of telomeric RNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_1901582 GO:0060464 biolink:BiologicalProcess lung lobe formation The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. go-plus.json http://purl.obolibrary.org/obo/GO_0060464 GO:0060465 biolink:BiologicalProcess pharynx development The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. go-plus.json pharyngeal development http://purl.obolibrary.org/obo/GO_0060465 GO:0035498 biolink:BiologicalProcess carnosine metabolic process The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine). go-plus.json carnosine metabolism http://purl.obolibrary.org/obo/GO_0035498 GO:1901580 biolink:BiologicalProcess regulation of telomeric RNA transcription from RNA pol II promoter Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. go-plus.json regulation of telomeric RNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_1901580 GO:0035499 biolink:BiologicalProcess carnosine biosynthetic process The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine). go-plus.json carnosine anabolism|carnosine synthesis|carnosine formation|carnosine biosynthesis http://purl.obolibrary.org/obo/GO_0035499 GO:0060466 biolink:BiologicalProcess activation of meiosis involved in egg activation Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation. go-plus.json reactivation of meiosis after fertilization|resumption of meiosis involved in egg activation http://purl.obolibrary.org/obo/GO_0060466 GO:0060467 biolink:BiologicalProcess negative regulation of fertilization Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). go-plus.json http://purl.obolibrary.org/obo/GO_0060467 GO:0060468 biolink:BiologicalProcess prevention of polyspermy The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. go-plus.json negative regulation of fertilization involved in egg activation|polyspermy block http://purl.obolibrary.org/obo/GO_0060468 GO:0060469 biolink:BiologicalProcess positive regulation of transcription involved in egg activation Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation. go-plus.json activation of the egg genome|activation of the maternal genome http://purl.obolibrary.org/obo/GO_0060469 GO:0035490 biolink:BiologicalProcess regulation of leukotriene production involved in inflammatory response Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0035490 GO:0035491 biolink:BiologicalProcess positive regulation of leukotriene production involved in inflammatory response Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0035491 GO:0035492 biolink:BiologicalProcess negative regulation of leukotriene production involved in inflammatory response Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0035492 GO:0035493 biolink:BiologicalProcess SNARE complex assembly The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035493 GO:0035494 biolink:BiologicalProcess SNARE complex disassembly The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035494 GO:0035495 biolink:BiologicalProcess regulation of SNARE complex disassembly Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. go-plus.json http://purl.obolibrary.org/obo/GO_0035495 GO:1901589 biolink:CellularComponent axon microtubule bundle An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. NIF_Subcellular:sao707332678 go-plus.json axon microtubule fascicle|microtubule bundle of axon|microtubule fascicle of axon http://purl.obolibrary.org/obo/GO_1901589 GO:1901587 biolink:BiologicalProcess positive regulation of acid-sensing ion channel activity Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity. go-plus.json positive regulation of ASIC activity|up-regulation of acid-sensing ion channel activity|activation of ASIC activity|up-regulation of ASIC activity|upregulation of acid-sensing ion channel activity|upregulation of ASIC activity|up regulation of acid-sensing ion channel activity|activation of acid-sensing ion channel activity|up regulation of ASIC activity http://purl.obolibrary.org/obo/GO_1901587 GO:0060490 biolink:BiologicalProcess lateral sprouting involved in lung morphogenesis The process in which a branch forms along the side of the lung epithelial tube. go-plus.json http://purl.obolibrary.org/obo/GO_0060490 GO:1901588 biolink:CellularComponent dendritic microtubule Any microtubule in a dendrite, a neuron projection. NIF_Subcellular:sao110773650 go-plus.json microtubulus of dendrite|microtubule of dendrite http://purl.obolibrary.org/obo/GO_1901588 GO:0060491 biolink:BiologicalProcess regulation of cell projection assembly Any process that modulates the rate, frequency, or extent of cell projection assembly. go-plus.json regulation of cell projection formation http://purl.obolibrary.org/obo/GO_0060491 GO:1901585 biolink:BiologicalProcess regulation of acid-sensing ion channel activity Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity. go-plus.json regulation of ASIC activity http://purl.obolibrary.org/obo/GO_1901585 GO:0060492 biolink:BiologicalProcess lung induction The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung. go-plus.json http://purl.obolibrary.org/obo/GO_0060492 GO:0060493 biolink:BiologicalProcess mesenchymal-endodermal cell signaling involved in lung induction Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud. go-plus.json mesenchymal-endodermal cell signalling involved in lung induction http://purl.obolibrary.org/obo/GO_0060493 GO:1901586 biolink:BiologicalProcess negative regulation of acid-sensing ion channel activity Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity. go-plus.json down-regulation of ASIC activity|negative regulation of ASIC activity|inhibition of acid-sensing ion channel activity|inhibition of ASIC activity|down regulation of acid-sensing ion channel activity|downregulation of acid-sensing ion channel activity|down regulation of ASIC activity|downregulation of ASIC activity|down-regulation of acid-sensing ion channel activity http://purl.obolibrary.org/obo/GO_1901586 GO:1901583 biolink:BiologicalProcess tetrapeptide transmembrane transport The directed movement of tetrapeptide across a membrane. go-plus.json tetrapeptide membrane transport http://purl.obolibrary.org/obo/GO_1901583 GO:0060494 biolink:BiologicalProcess inductive mesenchymal-endodermal cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell. go-plus.json inductive mesenchymal-endodermal cell signalling http://purl.obolibrary.org/obo/GO_0060494 GO:1901584 biolink:MolecularActivity tetrapeptide transmembrane transporter activity Enables the transfer of tetrapeptide from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901584 GO:0060495 biolink:BiologicalProcess cell-cell signaling involved in lung development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure. go-plus.json cell-cell signalling involved in lung development http://purl.obolibrary.org/obo/GO_0060495 GO:1901592 biolink:BiologicalProcess negative regulation of double-strand break repair via break-induced replication Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication. go-plus.json inhibition of double-strand break repair via break-induced replication|down-regulation of double-strand break repair via break-induced replication|downregulation of double-strand break repair via break-induced replication|down regulation of double-strand break repair via break-induced replication http://purl.obolibrary.org/obo/GO_1901592 GO:0060496 biolink:BiologicalProcess mesenchymal-epithelial cell signaling involved in lung development Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung. go-plus.json mesenchymal-epithelial cell signalling involved in lung development http://purl.obolibrary.org/obo/GO_0060496 GO:0035485 biolink:MolecularActivity adenine/guanine mispair binding Binding to a double-stranded DNA region containing an A/G mispair. go-plus.json A/G mispair binding|G/A mispair binding|guanine-adenine mispair binding http://purl.obolibrary.org/obo/GO_0035485 GO:1901593 biolink:BiologicalProcess response to GW 7647 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901593 GO:0060497 biolink:BiologicalProcess mesenchymal-endodermal cell signaling Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell. go-plus.json mesenchymal-endodermal cell signalling http://purl.obolibrary.org/obo/GO_0060497 GO:0035486 biolink:MolecularActivity cytosine/cytosine mispair binding Binding to a double-stranded DNA region containing a C/C mispair. go-plus.json C/C mispair binding http://purl.obolibrary.org/obo/GO_0035486 GO:0035487 biolink:MolecularActivity thymine/thymine mispair binding Binding to a double-stranded DNA region containing a T/T mispair. go-plus.json T/T mispair binding http://purl.obolibrary.org/obo/GO_0035487 GO:0060498 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in lung bud formation The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud. go-plus.json retinoic acid receptor signalling pathway involved in lung bud formation http://purl.obolibrary.org/obo/GO_0060498 GO:0035488 biolink:MolecularActivity cytosine/thymine mispair binding Binding to a double-stranded DNA region containing a C/T mispair. go-plus.json T/C mispair binding|thymine/cytosine mispair binding|C/T mispair binding http://purl.obolibrary.org/obo/GO_0035488 GO:1901591 biolink:BiologicalProcess regulation of double-strand break repair via break-induced replication Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication. go-plus.json http://purl.obolibrary.org/obo/GO_1901591 GO:0060499 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in lung induction The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus. go-plus.json fibroblast growth factor receptor signalling pathway involved in lung induction http://purl.obolibrary.org/obo/GO_0060499 GO:0035489 biolink:MolecularActivity guanine/guanine mispair binding Binding to a double-stranded DNA region containing a G/G mispair. go-plus.json G/G mispair binding http://purl.obolibrary.org/obo/GO_0035489 GO:0035480 biolink:BiologicalProcess regulation of Notch signaling pathway involved in heart induction Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. go-plus.json regulation of Notch signalling pathway involved in heart induction http://purl.obolibrary.org/obo/GO_0035480 GO:0035481 biolink:BiologicalProcess positive regulation of Notch signaling pathway involved in heart induction Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. go-plus.json positive regulation of Notch signalling pathway involved in heart induction http://purl.obolibrary.org/obo/GO_0035481 GO:0035482 biolink:BiologicalProcess gastric motility The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum. go-plus.json http://purl.obolibrary.org/obo/GO_0035482 GO:0035483 biolink:BiologicalProcess gastric emptying The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. go-plus.json http://purl.obolibrary.org/obo/GO_0035483 GO:0035484 biolink:MolecularActivity adenine/adenine mispair binding Binding to a double-stranded DNA region containing an A/A mispair. go-plus.json A/A mispair binding http://purl.obolibrary.org/obo/GO_0035484 GO:1901598 biolink:BiologicalProcess (-)-pinoresinol metabolic process The chemical reactions and pathways involving (-)-pinoresinol. go-plus.json (-)-pinoresinol metabolism http://purl.obolibrary.org/obo/GO_1901598 GO:1901599 biolink:BiologicalProcess (-)-pinoresinol biosynthetic process The chemical reactions and pathways resulting in the formation of (-)-pinoresinol. go-plus.json (-)-pinoresinol anabolism|(-)-pinoresinol synthesis|(-)-pinoresinol formation|(-)-pinoresinol biosynthesis http://purl.obolibrary.org/obo/GO_1901599 GO:0060480 biolink:BiologicalProcess lung goblet cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins. go-plus.json pulmonary goblet cell differentiation http://purl.obolibrary.org/obo/GO_0060480 GO:0060481 biolink:BiologicalProcess lobar bronchus epithelium development The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus. go-plus.json http://purl.obolibrary.org/obo/GO_0060481 GO:1901596 biolink:BiologicalProcess response to reversine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901596 GO:1901597 biolink:BiologicalProcess response to carbendazim Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901597 GO:0060482 biolink:BiologicalProcess lobar bronchus development The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi. go-plus.json http://purl.obolibrary.org/obo/GO_0060482 GO:1901594 biolink:BiologicalProcess response to capsazepine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901594 GO:0060483 biolink:BiologicalProcess lobar bronchus mesenchyme development The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus. go-plus.json http://purl.obolibrary.org/obo/GO_0060483 GO:1901595 biolink:BiologicalProcess response to hesperadin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901595 GO:0060484 biolink:BiologicalProcess lung-associated mesenchyme development The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. go-plus.json lung mesenchyme development|pulmonary mesenchyme development http://purl.obolibrary.org/obo/GO_0060484 GO:0060485 biolink:BiologicalProcess mesenchyme development The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. go-plus.json mesenchymal development http://purl.obolibrary.org/obo/GO_0060485 GO:0035474 biolink:BiologicalProcess selective angioblast sprouting The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel. go-plus.json http://purl.obolibrary.org/obo/GO_0035474 GO:0060486 biolink:BiologicalProcess club cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. go-plus.json Clara cell differentiation http://purl.obolibrary.org/obo/GO_0060486 GO:0035475 biolink:BiologicalProcess angioblast cell migration involved in selective angioblast sprouting The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations. go-plus.json http://purl.obolibrary.org/obo/GO_0035475 GO:0035476 biolink:BiologicalProcess angioblast cell migration The orderly movement of angioblasts, cells involved in blood vessel morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0035476 GO:0060487 biolink:BiologicalProcess lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. go-plus.json pulmonary epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0060487 GO:0035477 biolink:BiologicalProcess regulation of angioblast cell migration involved in selective angioblast sprouting Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting. go-plus.json http://purl.obolibrary.org/obo/GO_0035477 GO:0060488 biolink:BiologicalProcess orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis The process in which a lung bud bifurcates perpendicular to the plane of the previous bud. go-plus.json perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis http://purl.obolibrary.org/obo/GO_0060488 GO:0060489 biolink:BiologicalProcess planar dichotomous subdivision of terminal units involved in lung branching morphogenesis The process in which a lung bud bifurcates parallel to the plane of the previous bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060489 GO:0035478 biolink:MolecularActivity chylomicron binding Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. go-plus.json http://purl.obolibrary.org/obo/GO_0035478 GO:0035479 biolink:BiologicalProcess angioblast cell migration from lateral mesoderm to midline The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_0035479 GO:0035470 biolink:BiologicalProcess positive regulation of vascular wound healing Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_0035470 GO:0035471 biolink:BiologicalProcess luteinizing hormone signaling pathway involved in ovarian follicle development The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure. go-plus.json luteinizing hormone signalling pathway involved in ovarian follicle development http://purl.obolibrary.org/obo/GO_0035471 GO:0035472 biolink:MolecularActivity choriogonadotropin hormone receptor activity Combining with the choriogonadotropin hormone to initiate a change in cell activity. go-plus.json chorionic gonadotropin hormone receptor|chorio-gonadotrophin receptor activity|CG receptor activity http://purl.obolibrary.org/obo/GO_0035472 GO:0035473 biolink:MolecularActivity lipase binding Binding to a lipase. go-plus.json http://purl.obolibrary.org/obo/GO_0035473 CHEBI:141282 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 36:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141282 CHEBI:141283 biolink:ChemicalSubstance (6E)-nerolidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_141283 chebi_ph7_3 NCBITaxon:2301119 biolink:OrganismalEntity Rhabditomorpha go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2301119 CHEBI:141280 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 36:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141280 CHEBI:141281 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 36:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141281 NCBITaxon:2301116 biolink:OrganismalEntity Rhabditina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2301116 GO:0035463 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves. go-plus.json TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|TGFbeta receptor signaling pathway involved in determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_0035463 GO:0035464 biolink:BiologicalProcess regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves. go-plus.json regulation of TGFbeta receptor signaling pathway involved in determination of left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|regulation of TGFbeta receptor signalling pathway involved in determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_0035464 GO:0035465 biolink:BiologicalProcess obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves. go-plus.json regulation of TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry http://purl.obolibrary.org/obo/GO_0035465 GO:0035466 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035466 GO:0035467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035467 GO:0035468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035468 GO:0035469 biolink:BiologicalProcess determination of pancreatic left/right asymmetry Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0035469 GO:0035460 biolink:MolecularActivity L-ascorbate 6-phosphate lactonase activity Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate. RHEA:28803 go-plus.json http://purl.obolibrary.org/obo/GO_0035460 GO:0035461 biolink:BiologicalProcess vitamin transmembrane transport The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json vitamin membrane transport http://purl.obolibrary.org/obo/GO_0035461 GO:0035462 biolink:BiologicalProcess determination of left/right asymmetry in diencephalon The establishment of the diencephalon with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0035462 CHEBI:141271 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 32:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141271 CHEBI:141272 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 34:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141272 CHEBI:141270 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 32:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141270 CHEBI:141279 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 36:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141279 CHEBI:141277 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 34:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141277 CHEBI:141278 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141278 CHEBI:141275 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 34:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141275 CHEBI:141276 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 34:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141276 CHEBI:141273 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 34:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141273 CHEBI:141274 biolink:ChemicalSubstance sulfoquinovosyldiacylglycerol 34:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141274 GO:0035452 biolink:CellularComponent extrinsic component of plastid membrane The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to plastid membrane|peripheral to plastid membrane http://purl.obolibrary.org/obo/GO_0035452 GO:0035453 biolink:CellularComponent extrinsic component of plastid inner membrane The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to plastid inner membrane|peripheral to plastid inner membrane http://purl.obolibrary.org/obo/GO_0035453 GO:0035454 biolink:CellularComponent extrinsic component of stromal side of plastid inner membrane The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to stromal side of plastid inner membrane|peripheral to stromal side of plastid inner membrane|extrinsic to stromal leaflet of plastid inner membrane http://purl.obolibrary.org/obo/GO_0035454 GO:0035455 biolink:BiologicalProcess response to interferon-alpha Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. go-plus.json response to lymphoblastoid interferon|response to interferon alfa-n3|response to interferon alfa-n1|response to lymphoblast interferon|response to leukocyte interferon http://purl.obolibrary.org/obo/GO_0035455 GO:0035456 biolink:BiologicalProcess response to interferon-beta Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. go-plus.json response to fiblaferon|response to interferon beta|response to beta-1 interferon|response to fibroblast interferon http://purl.obolibrary.org/obo/GO_0035456 GO:0035457 biolink:BiologicalProcess cellular response to interferon-alpha Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. go-plus.json cellular response to leukocyte interferon|cellular response to interferon alfa-n3|cellular response to interferon alfa-n1|cellular response to lymphoblastoid interferon|cellular response to lymphoblast interferon http://purl.obolibrary.org/obo/GO_0035457 GO:0035458 biolink:BiologicalProcess cellular response to interferon-beta Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. go-plus.json cellular response to beta-1 interferon|cellular response to fibroblast interferon|cellular response to fiblaferon http://purl.obolibrary.org/obo/GO_0035458 GO:0035459 biolink:BiologicalProcess vesicle cargo loading The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle. go-plus.json cargo loading into vesicle|cargo selection http://purl.obolibrary.org/obo/GO_0035459 GO:0035450 biolink:CellularComponent extrinsic component of lumenal side of plastid thylakoid membrane The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to lumenal side of plastid thylakoid membrane|peripheral to lumenal side of plastid thylakoid membrane|extrinsic to lumenal leaflet of plastid thylakoid membrane http://purl.obolibrary.org/obo/GO_0035450 GO:0035451 biolink:CellularComponent extrinsic component of stromal side of plastid thylakoid membrane The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region. go-plus.json extrinsic to stromal side of plastid thylakoid membrane|peripheral to stromal side of plastid thylakoid membrane|extrinsic to stromal leaflet of plastid thylakoid membrane http://purl.obolibrary.org/obo/GO_0035451 GO:0035449 biolink:CellularComponent extrinsic component of plastid thylakoid membrane The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json peripheral to plastid thylakoid membrane|extrinsic to plastid thylakoid membrane http://purl.obolibrary.org/obo/GO_0035449 GO:0035441 biolink:BiologicalProcess cell migration involved in vasculogenesis The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. go-plus.json http://purl.obolibrary.org/obo/GO_0035441 GO:0035442 biolink:BiologicalProcess dipeptide transmembrane transport The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond. go-plus.json dipeptide membrane transport http://purl.obolibrary.org/obo/GO_0035442 GO:0035443 biolink:BiologicalProcess tripeptide transmembrane transport The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds. go-plus.json tripeptide membrane transport http://purl.obolibrary.org/obo/GO_0035443 GO:0035444 biolink:BiologicalProcess nickel cation transmembrane transport The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore. go-plus.json nickel cation membrane transport http://purl.obolibrary.org/obo/GO_0035444 GO:0035445 biolink:BiologicalProcess borate transmembrane transport The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals. go-plus.json borate membrane transport|boron transmembrane transport http://purl.obolibrary.org/obo/GO_0035445 GO:0035446 biolink:MolecularActivity cysteine-glucosaminylinositol ligase activity Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins. MetaCyc:RXN1G-4|EC:6.3.1.13|RHEA:26176 go-plus.json desacetylmycothiol synthase|L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase|MshC ligase http://purl.obolibrary.org/obo/GO_0035446 GO:0035447 biolink:MolecularActivity mycothiol synthase activity Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol. MetaCyc:MONOMER-9684 go-plus.json acetyl-CoA:Cys-GlcN-Ins acetyltransferase http://purl.obolibrary.org/obo/GO_0035447 GO:0035448 biolink:CellularComponent extrinsic component of thylakoid membrane The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to thylakoid membrane|peripheral to thylakoid membrane http://purl.obolibrary.org/obo/GO_0035448 GO:0035440 biolink:BiologicalProcess tuberculosinol biosynthetic process The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria. MetaCyc:PWY-5935 go-plus.json tuberculosinol biosynthesis|halima-5,6,dien-15-ol biosynthetic process|halima-5,6,dien-15-ol biosynthesis http://purl.obolibrary.org/obo/GO_0035440 GO:0035438 biolink:MolecularActivity cyclic-di-GMP binding Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate. go-plus.json c-di-GMP binding|3',5'-cyclic di-GMP binding|cyclic dinucleotide di-GMP binding http://purl.obolibrary.org/obo/GO_0035438 GO:0035439 biolink:MolecularActivity halimadienyl-diphosphate synthase activity Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate. EC:5.5.1.16|RHEA:25621 go-plus.json halimadienyl diphosphate synthase activity|halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing) http://purl.obolibrary.org/obo/GO_0035439 GO:0035430 biolink:BiologicalProcess regulation of gluconate transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore. go-plus.json regulation of gluconate transport|regulation of gluconate membrane transport http://purl.obolibrary.org/obo/GO_0035430 GO:0035431 biolink:BiologicalProcess negative regulation of gluconate transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. go-plus.json negative regulation of gluconate transport|inhibition of gluconate transport|negative regulation of gluconate membrane transport|down regulation of gluconate transport|downregulation of gluconate transport|down-regulation of gluconate transport http://purl.obolibrary.org/obo/GO_0035431 GO:0035432 biolink:BiologicalProcess positive regulation of gluconate transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. go-plus.json up-regulation of gluconate transport|induction of gluconate transport|upregulation of gluconate transport|positive regulation of gluconate membrane transport|up regulation of gluconate transport|activation of gluconate transport|stimulation of gluconate transport|positive regulation of gluconate transport http://purl.obolibrary.org/obo/GO_0035432 GO:0035433 biolink:BiologicalProcess acetate transmembrane transport The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid. go-plus.json acetate membrane transport http://purl.obolibrary.org/obo/GO_0035433 GO:0035434 biolink:BiologicalProcess copper ion transmembrane transport The directed movement of copper cation across a membrane. go-plus.json copper cation transmembrane transport|copper ion membrane transport http://purl.obolibrary.org/obo/GO_0035434 CHEBI:61702 biolink:ChemicalSubstance dinoflagellate luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61702 GO:0035435 biolink:BiologicalProcess phosphate ion transmembrane transport The process in which a phosphate is transported across a membrane. go-plus.json phosphate ion membrane transport http://purl.obolibrary.org/obo/GO_0035435 CHEBI:61703 biolink:ChemicalSubstance nonclassic icosanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61703 CHEBI:61700 biolink:ChemicalSubstance (+)-valencene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61700 chebi_ph7_3 GO:0035436 biolink:BiologicalProcess triose phosphate transmembrane transport The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester. go-plus.json triose phosphate membrane transport|triose phosphate transmembrane transport http://purl.obolibrary.org/obo/GO_0035436 GO:0035437 biolink:BiologicalProcess maintenance of protein localization in endoplasmic reticulum Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum. go-plus.json maintenance of protein location in endoplasmic reticulum|retention of protein in ER|protein-endoplasmic reticulum retention|maintenance of protein localization in ER|retention of protein in endoplasmic reticulum|maintenance of protein localisation in endoplasmic reticulum|maintenance of protein location in ER|protein-ER retention http://purl.obolibrary.org/obo/GO_0035437 CHEBI:61701 biolink:ChemicalSubstance L-ascorbic acid 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61701 CHEBI:61706 biolink:ChemicalSubstance dinoflagellate luciferin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61706 CHEBI:61707 biolink:ChemicalSubstance oxidized dinoflagellate luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61707 CHEBI:61704 biolink:ChemicalSubstance oxoicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61704 CHEBI:61705 biolink:ChemicalSubstance 3-demethylubiquinol-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61705 chebi_ph7_3 CHEBI:61708 biolink:ChemicalSubstance oxidized dinoflagellate luciferin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61708 chebi_ph7_3 CHEBI:22102 biolink:ChemicalSubstance UDP-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22102 CHEBI:36749 biolink:ChemicalSubstance dipyrrins go-plus.json http://purl.obolibrary.org/obo/CHEBI_36749 CHEBI:36742 biolink:ChemicalSubstance p-menthan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_36742 chebi_ph7_3 CHEBI:36743 biolink:ChemicalSubstance germacrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36743 CHEBI:12777 biolink:ChemicalSubstance vitamin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_12777 CHEBI:36740 biolink:ChemicalSubstance alpha-pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36740 chebi_ph7_3 CHEBI:36741 biolink:ChemicalSubstance phycoerythrobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_36741 CHEBI:36745 biolink:ChemicalSubstance cedrane sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36745 CHEBI:36753 biolink:ChemicalSubstance eremophilane sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36753 CHEBI:36754 biolink:ChemicalSubstance vetispirane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36754 chebi_ph7_3 CHEBI:36751 biolink:ChemicalSubstance pyrrole-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36751 CHEBI:36757 biolink:ChemicalSubstance farnesane sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36757 CHEBI:36758 biolink:ChemicalSubstance apo carotenoid sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36758 CHEBI:36756 biolink:ChemicalSubstance farnesane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36756 chebi_ph7_3 CHEBI:22119 biolink:ChemicalSubstance UDP-N-acetylmannosaminouronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22119 CHEBI:36750 biolink:ChemicalSubstance (R)-1-pyrroline-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36750 GO:1901509 biolink:BiologicalProcess regulation of endothelial tube morphogenesis Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1901509 GO:1901507 biolink:BiologicalProcess negative regulation of acylglycerol transport Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport. go-plus.json down-regulation of acylglycerol transport|inhibition of glyceride transport|downregulation of acylglycerol transport|down regulation of acylglycerol transport|inhibition of acylglycerol transport|down regulation of glyceride transport|downregulation of glyceride transport|negative regulation of glyceride transport|down-regulation of glyceride transport http://purl.obolibrary.org/obo/GO_1901507 GO:1901508 biolink:BiologicalProcess positive regulation of acylglycerol transport Any process that activates or increases the frequency, rate or extent of acylglycerol transport. go-plus.json up-regulation of glyceride transport|up regulation of acylglycerol transport|upregulation of glyceride transport|upregulation of acylglycerol transport|up regulation of glyceride transport|activation of glyceride transport|positive regulation of glyceride transport|up-regulation of acylglycerol transport|activation of acylglycerol transport http://purl.obolibrary.org/obo/GO_1901508 GO:1901505 biolink:MolecularActivity carbohydrate derivative transmembrane transporter activity Enables the transfer of carbohydrate derivative from one side of a membrane to the other. go-plus.json carbohydrate derivative transporter activity http://purl.obolibrary.org/obo/GO_1901505 GO:1901506 biolink:BiologicalProcess regulation of acylglycerol transport Any process that modulates the frequency, rate or extent of acylglycerol transport. go-plus.json regulation of glyceride transport http://purl.obolibrary.org/obo/GO_1901506 GO:1901503 biolink:BiologicalProcess ether biosynthetic process The chemical reactions and pathways resulting in the formation of ether. go-plus.json ether biosynthesis|ether anabolism|ether synthesis|ether formation http://purl.obolibrary.org/obo/GO_1901503 GO:1901504 biolink:BiologicalProcess triazole transport The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901504 GO:1901501 biolink:BiologicalProcess response to xylene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901501 CHEBI:36728 biolink:ChemicalSubstance 20-hydroxypregn-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_36728 chebi_ph7_3 CHEBI:36729 biolink:ChemicalSubstance (20R)-20-hydroxypregn-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_36729 chebi_ph7_3 GO:1901502 biolink:BiologicalProcess ether catabolic process The chemical reactions and pathways resulting in the breakdown of ether. go-plus.json ether degradation|ether catabolism|ether breakdown http://purl.obolibrary.org/obo/GO_1901502 CHEBI:36726 biolink:ChemicalSubstance 17,20-dihydroxypregn-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_36726 chebi_ph7_3 GO:1901500 biolink:BiologicalProcess response to p-xylene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901500 CHEBI:36727 biolink:ChemicalSubstance 1-alkyl-2,3-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_36727 NCBITaxon:47757 biolink:OrganismalEntity Adrianichthyidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_47757 CHEBI:36721 biolink:ChemicalSubstance pentachlorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_36721 GO:0060410 biolink:BiologicalProcess negative regulation of acetylcholine metabolic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0060410 GO:0060411 biolink:BiologicalProcess cardiac septum morphogenesis The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. go-plus.json heart septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 GO:0060412 biolink:BiologicalProcess ventricular septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. go-plus.json interventricular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060412 GO:0060413 biolink:BiologicalProcess atrial septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. go-plus.json interatrial septum morphogenesis http://purl.obolibrary.org/obo/GO_0060413 GO:0060414 biolink:BiologicalProcess aorta smooth muscle tissue morphogenesis The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0060414 GO:0060415 biolink:BiologicalProcess muscle tissue morphogenesis The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. go-plus.json http://purl.obolibrary.org/obo/GO_0060415 GO:0060416 biolink:BiologicalProcess response to growth hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. go-plus.json response to growth hormone stimulus http://purl.obolibrary.org/obo/GO_0060416 GO:0060417 biolink:CellularComponent yolk The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0060417 GO:0060418 biolink:CellularComponent yolk plasma Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed. go-plus.json http://purl.obolibrary.org/obo/GO_0060418 GO:0060419 biolink:BiologicalProcess heart growth The increase in size or mass of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060419 GO:1901518 biolink:BiologicalProcess aspyridone A biosynthetic process The chemical reactions and pathways resulting in the formation of aspyridone A. go-plus.json aspyridone A formation|aspyridone A biosynthesis|aspyridone A anabolism|aspyridone A synthesis http://purl.obolibrary.org/obo/GO_1901518 GO:1901519 biolink:BiologicalProcess aspyridone B metabolic process The chemical reactions and pathways involving aspyridone B. go-plus.json aspyridone B metabolism http://purl.obolibrary.org/obo/GO_1901519 GO:1901516 biolink:BiologicalProcess aspyridone A metabolic process The chemical reactions and pathways involving aspyridone A. go-plus.json aspyridone A metabolism http://purl.obolibrary.org/obo/GO_1901516 GO:1901517 biolink:BiologicalProcess aspyridone A catabolic process The chemical reactions and pathways resulting in the breakdown of aspyridone A. go-plus.json aspyridone A degradation|aspyridone A catabolism|aspyridone A breakdown http://purl.obolibrary.org/obo/GO_1901517 GO:1901514 biolink:MolecularActivity ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out). go-plus.json lipo-chitin oligosaccharide transmembrane-transporting ATPase activity http://purl.obolibrary.org/obo/GO_1901514 GO:1901515 biolink:MolecularActivity poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901515 GO:1901512 biolink:BiologicalProcess (-)-microperfuranone biosynthetic process The chemical reactions and pathways resulting in the formation of (-)-microperfuranone. go-plus.json (-)-microperfuranone biosynthesis|(-)-microperfuranone anabolism|(-)-microperfuranone synthesis|(-)-microperfuranone formation http://purl.obolibrary.org/obo/GO_1901512 CHEBI:36739 biolink:ChemicalSubstance fenchane monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36739 GO:1901513 biolink:MolecularActivity lipo-chitin oligosaccharide transmembrane transporter activity Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901513 GO:1901510 biolink:BiologicalProcess (-)-microperfuranone metabolic process The chemical reactions and pathways involving (-)-microperfuranone. go-plus.json (-)-microperfuranone metabolism http://purl.obolibrary.org/obo/GO_1901510 CHEBI:36737 biolink:ChemicalSubstance bilene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36737 GO:1901511 biolink:BiologicalProcess (-)-microperfuranone catabolic process The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone. go-plus.json (-)-microperfuranone degradation|(-)-microperfuranone breakdown|(-)-microperfuranone catabolism http://purl.obolibrary.org/obo/GO_1901511 CHEBI:36738 biolink:ChemicalSubstance biladiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36738 CHEBI:36732 biolink:ChemicalSubstance bilene-b go-plus.json http://purl.obolibrary.org/obo/CHEBI_36732 GO:0060400 biolink:BiologicalProcess negative regulation of growth hormone receptor signaling pathway Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. go-plus.json negative regulation of growth hormone receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060400 CHEBI:36730 biolink:ChemicalSubstance hydroxypregnenolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36730 CHEBI:36735 biolink:ChemicalSubstance biladienes go-plus.json http://purl.obolibrary.org/obo/CHEBI_36735 GO:0060401 biolink:BiologicalProcess cytosolic calcium ion transport The directed movement of calcium ions (Ca2+) into, out of or within the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0060401 GO:0060402 biolink:BiologicalProcess calcium ion transport into cytosol The directed movement of calcium ions (Ca2+) into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0060402 CHEBI:36736 biolink:ChemicalSubstance bilenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_36736 CHEBI:36733 biolink:ChemicalSubstance biladiene-ab go-plus.json http://purl.obolibrary.org/obo/CHEBI_36733 GO:0060403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060403 GO:0060404 biolink:BiologicalProcess axonemal microtubule depolymerization The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0060404 GO:0060405 biolink:BiologicalProcess regulation of penile erection Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. go-plus.json http://purl.obolibrary.org/obo/GO_0060405 GO:0060406 biolink:BiologicalProcess positive regulation of penile erection Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. go-plus.json http://purl.obolibrary.org/obo/GO_0060406 GO:0060407 biolink:BiologicalProcess negative regulation of penile erection Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. go-plus.json http://purl.obolibrary.org/obo/GO_0060407 GO:0060408 biolink:BiologicalProcess regulation of acetylcholine metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0060408 GO:0060409 biolink:BiologicalProcess positive regulation of acetylcholine metabolic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0060409 GO:1901529 biolink:BiologicalProcess positive regulation of anion channel activity Any process that activates or increases the frequency, rate or extent of anion channel activity. go-plus.json activation of anion channel activity|up regulation of anion channel activity|upregulation of anion channel activity|up-regulation of anion channel activity http://purl.obolibrary.org/obo/GO_1901529 GO:1901527 biolink:BiologicalProcess abscisic acid-activated signaling pathway involved in stomatal movement Any abscisic acid mediated signaling pathway that is involved in stomatal movement. go-plus.json abscisic acid mediated signalling involved in stomatal movement|abscisic acid mediated signaling pathway involved in stomatal movement http://purl.obolibrary.org/obo/GO_1901527 GO:1901528 biolink:BiologicalProcess hydrogen peroxide mediated signaling pathway involved in stomatal movement Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement. go-plus.json hydrogen peroxide mediated signalling pathway involved in stomatal movement|H2O2 mediated signaling pathway involved in stomatal movement http://purl.obolibrary.org/obo/GO_1901528 GO:1901525 biolink:BiologicalProcess negative regulation of mitophagy Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy. go-plus.json downregulation of macromitophagy|down regulation of macromitophagy|inhibition of macromitophagy|negative regulation of macromitophagy|down-regulation of macromitophagy http://purl.obolibrary.org/obo/GO_1901525 NCBITaxon:33170 biolink:OrganismalEntity Eremothecium go-plus.json Ashbya|Holleya http://purl.obolibrary.org/obo/NCBITaxon_33170 GO:1901526 biolink:BiologicalProcess positive regulation of mitophagy Any process that activates or increases the frequency, rate or extent of mitophagy. go-plus.json up regulation of macromitophagy|upregulation of macromitophagy|positive regulation of macromitophagy|up-regulation of macromitophagy|activation of macromitophagy http://purl.obolibrary.org/obo/GO_1901526 GO:1901523 biolink:BiologicalProcess icosanoid catabolic process The chemical reactions and pathways resulting in the breakdown of icosanoid. go-plus.json icosanoid catabolism|icosanoid degradation|icosanoid breakdown http://purl.obolibrary.org/obo/GO_1901523 CHEBI:224037 biolink:ChemicalSubstance 3-sulfinato-L-alaninate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_224037 GO:1901524 biolink:BiologicalProcess regulation of mitophagy Any process that modulates the frequency, rate or extent of macromitophagy. go-plus.json regulation of macromitophagy http://purl.obolibrary.org/obo/GO_1901524 CHEBI:36707 biolink:ChemicalSubstance 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36707 chebi_ph7_3 GO:1901521 biolink:BiologicalProcess aspyridone B biosynthetic process The chemical reactions and pathways resulting in the formation of aspyridone B. go-plus.json aspyridone B anabolism|aspyridone B synthesis|aspyridone B formation|aspyridone B biosynthesis http://purl.obolibrary.org/obo/GO_1901521 GO:1901522 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus. go-plus.json positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus|activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_1901522 GO:1901520 biolink:BiologicalProcess aspyridone B catabolic process The chemical reactions and pathways resulting in the breakdown of aspyridone B. go-plus.json aspyridone B degradation|aspyridone B catabolism|aspyridone B breakdown http://purl.obolibrary.org/obo/GO_1901520 CHEBI:36709 biolink:ChemicalSubstance aminoquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_36709 GO:0060430 biolink:BiologicalProcess lung saccule development The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells. go-plus.json lung saccular development http://purl.obolibrary.org/obo/GO_0060430 GO:0060431 biolink:BiologicalProcess primary lung bud formation The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. go-plus.json lung formation http://purl.obolibrary.org/obo/GO_0060431 GO:0060432 biolink:BiologicalProcess lung pattern specification process Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate. go-plus.json http://purl.obolibrary.org/obo/GO_0060432 GO:0060433 biolink:BiologicalProcess bronchus development The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. go-plus.json http://purl.obolibrary.org/obo/GO_0060433 CHEBI:36702 biolink:ChemicalSubstance 2-acyl-1-alkyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36702 chebi_ph7_3 GO:0060434 biolink:BiologicalProcess bronchus morphogenesis The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. go-plus.json http://purl.obolibrary.org/obo/GO_0060434 GO:0060435 biolink:BiologicalProcess bronchiole development The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. go-plus.json http://purl.obolibrary.org/obo/GO_0060435 CHEBI:36703 biolink:ChemicalSubstance tetrachloro-1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36703 chebi_ph7_3 CHEBI:36700 biolink:ChemicalSubstance phosphocholines go-plus.json http://purl.obolibrary.org/obo/CHEBI_36700 GO:0060436 biolink:BiologicalProcess bronchiole morphogenesis The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. go-plus.json http://purl.obolibrary.org/obo/GO_0060436 GO:0060437 biolink:BiologicalProcess lung growth The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. go-plus.json http://purl.obolibrary.org/obo/GO_0060437 GO:0060438 biolink:BiologicalProcess trachea development The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. go-plus.json http://purl.obolibrary.org/obo/GO_0060438 GO:0060439 biolink:BiologicalProcess trachea morphogenesis The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. go-plus.json http://purl.obolibrary.org/obo/GO_0060439 GO:1901538 biolink:BiologicalProcess changes to DNA methylation involved in embryo development The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression. go-plus.json DNA methylation or demethylation involved in embryogenesis|changes in DNA methylation involved in embryo development|DNA methylation or demethylation involved in embryonal development|changes in DNA methylation involved in embryonal development|changes in DNA methylation involved in embryogenesis http://purl.obolibrary.org/obo/GO_1901538 GO:1901539 biolink:BiologicalProcess ent-pimara-8(14),15-diene metabolic process The chemical reactions and pathways involving ent-pimara-8(14),15-diene. go-plus.json ent-pimara-8(14),15-diene metabolism http://purl.obolibrary.org/obo/GO_1901539 GO:1901536 biolink:BiologicalProcess negative regulation of DNA demethylation Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation. go-plus.json down regulation of DNA demethylation|downregulation of DNA demethylation|down-regulation of DNA demethylation|inhibition of DNA demethylation http://purl.obolibrary.org/obo/GO_1901536 GO:1901537 biolink:BiologicalProcess positive regulation of DNA demethylation Any process that activates or increases the frequency, rate or extent of DNA demethylation. go-plus.json upregulation of DNA demethylation|up regulation of DNA demethylation|activation of DNA demethylation|up-regulation of DNA demethylation http://purl.obolibrary.org/obo/GO_1901537 GO:1901534 biolink:BiologicalProcess positive regulation of hematopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. go-plus.json up regulation of hematopoietic progenitor cell differentiation|up-regulation of haemopoietic progenitor cell differentiation|positive regulation of hemopoietic progenitor cell differentiation|upregulation of haematopoietic progenitor cell differentiation|upregulation of hemopoietic progenitor cell differentiation|activation of haemopoietic progenitor cell differentiation|activation of hematopoietic progenitor cell differentiation|positive regulation of haemopoietic progenitor cell differentiation|up-regulation of haematopoietic progenitor cell differentiation|up-regulation of hematopoietic progenitor cell differentiation|up regulation of haemopoietic progenitor cell differentiation|up regulation of hemopoietic progenitor cell differentiation|activation of hemopoietic progenitor cell differentiation|activation of haematopoietic progenitor cell differentiation|upregulation of hematopoietic progenitor cell differentiation|upregulation of haemopoietic progenitor cell differentiation|positive regulation of haematopoietic progenitor cell differentiation|up regulation of haematopoietic progenitor cell differentiation|up-regulation of hemopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901534 CHEBI:36717 biolink:ChemicalSubstance monochlorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_36717 GO:1901535 biolink:BiologicalProcess regulation of DNA demethylation Any process that modulates the frequency, rate or extent of DNA demethylation. go-plus.json http://purl.obolibrary.org/obo/GO_1901535 GO:1901532 biolink:BiologicalProcess regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. go-plus.json regulation of haemopoietic progenitor cell differentiation|regulation of hemopoietic progenitor cell differentiation|regulation of haematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 GO:1901533 biolink:BiologicalProcess negative regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. go-plus.json down regulation of haematopoietic progenitor cell differentiation|negative regulation of hemopoietic progenitor cell differentiation|down-regulation of hematopoietic progenitor cell differentiation|down regulation of hemopoietic progenitor cell differentiation|negative regulation of haemopoietic progenitor cell differentiation|down-regulation of haemopoietic progenitor cell differentiation|inhibition of haematopoietic progenitor cell differentiation|downregulation of hemopoietic progenitor cell differentiation|downregulation of haemopoietic progenitor cell differentiation|inhibition of hematopoietic progenitor cell differentiation|down-regulation of haematopoietic progenitor cell differentiation|down regulation of haemopoietic progenitor cell differentiation|negative regulation of haematopoietic progenitor cell differentiation|down-regulation of hemopoietic progenitor cell differentiation|down regulation of hematopoietic progenitor cell differentiation|inhibition of hemopoietic progenitor cell differentiation|inhibition of haemopoietic progenitor cell differentiation|downregulation of hematopoietic progenitor cell differentiation|downregulation of haematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901533 GO:1901530 biolink:BiologicalProcess response to hypochlorite Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901530 GO:1901531 biolink:MolecularActivity hypochlorite binding Binding to hypochlorite. go-plus.json http://purl.obolibrary.org/obo/GO_1901531 GO:0060420 biolink:BiologicalProcess regulation of heart growth Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060420 GO:0060421 biolink:BiologicalProcess positive regulation of heart growth Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060421 GO:0060422 biolink:MolecularActivity peptidyl-dipeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain. Wikipedia:ACE_inhibitor go-plus.json http://purl.obolibrary.org/obo/GO_0060422 CHEBI:36713 biolink:ChemicalSubstance 5alpha-androstane-3alpha,17beta-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_36713 chebi_ph7_3 GO:0060423 biolink:BiologicalProcess foregut regionalization The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place. go-plus.json http://purl.obolibrary.org/obo/GO_0060423 GO:0060424 biolink:BiologicalProcess lung field specification The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop. go-plus.json lung specification http://purl.obolibrary.org/obo/GO_0060424 GO:0060425 biolink:BiologicalProcess lung morphogenesis The process in which the anatomical structures of the lung are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060425 CHEBI:36711 biolink:ChemicalSubstance phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36711 GO:0060426 biolink:BiologicalProcess lung vasculature development The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. go-plus.json pulmonary vasculature development http://purl.obolibrary.org/obo/GO_0060426 CHEBI:36712 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36712 GO:0060427 biolink:BiologicalProcess lung connective tissue development The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. go-plus.json pulmonary connective tissue development http://purl.obolibrary.org/obo/GO_0060427 GO:0060428 biolink:BiologicalProcess lung epithelium development The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. go-plus.json pulmonary epithelium development http://purl.obolibrary.org/obo/GO_0060428 GO:0060429 biolink:BiologicalProcess epithelium development The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060429 goslim_drosophila OIO:hasBroadSynonym biolink:OntologyClass has_broad_synonym go-plus.json http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym NCBITaxon:33169 biolink:OrganismalEntity Eremothecium gossypii go-plus.json Ashbya gossypii|Nematospora gossypii http://purl.obolibrary.org/obo/NCBITaxon_33169 NCBITaxon:33154 biolink:OrganismalEntity Opisthokonta go-plus.json opisthokonts|Fungi/Metazoa group http://purl.obolibrary.org/obo/NCBITaxon_33154 GO:1901549 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901549 GO:1901547 biolink:BiologicalProcess negative regulation of synaptic vesicle lumen acidification Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification. go-plus.json down regulation of synaptic vesicle lumen acidification|inhibition of synaptic vesicle lumen acidification|inhibition of synaptic vesicle lumen pH reduction|negative regulation of proton loading|down regulation of synaptic vesicle lumen pH reduction|downregulation of synaptic vesicle lumen pH reduction|down-regulation of synaptic vesicle lumen acidification|down-regulation of synaptic vesicle lumen pH reduction|negative regulation of synaptic vesicle lumen pH reduction|downregulation of synaptic vesicle lumen acidification http://purl.obolibrary.org/obo/GO_1901547 GO:1901548 biolink:BiologicalProcess positive regulation of synaptic vesicle lumen acidification Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification. go-plus.json up-regulation of synaptic vesicle lumen pH reduction|upregulation of synaptic vesicle lumen acidification|upregulation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen acidification|up-regulation of synaptic vesicle lumen acidification|positive regulation of proton loading|up regulation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen pH reduction|positive regulation of synaptic vesicle lumen pH reduction|up regulation of synaptic vesicle lumen acidification http://purl.obolibrary.org/obo/GO_1901548 GO:1901545 biolink:BiologicalProcess response to raffinose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901545 CHEBI:165279 biolink:ChemicalSubstance 11-HpETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_165279 GO:1901546 biolink:BiologicalProcess regulation of synaptic vesicle lumen acidification Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification. go-plus.json regulation of synaptic vesicle lumen pH reduction|regulation of synaptic vesicle lumen proton loading http://purl.obolibrary.org/obo/GO_1901546 goslim_synapse GO:1901543 biolink:BiologicalProcess negative regulation of ent-pimara-8(14),15-diene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process. go-plus.json downregulation of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene anabolism|negative regulation of ent-pimara-8(14),15-diene anabolism|down regulation of ent-pimara-8(14),15-diene biosynthesis|down regulation of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene synthesis|negative regulation of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene biosynthesis|inhibition of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene formation|inhibition of ent-pimara-8(14),15-diene anabolism|negative regulation of ent-pimara-8(14),15-diene formation|inhibition of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene formation|down regulation of ent-pimara-8(14),15-diene anabolism|down-regulation of ent-pimara-8(14),15-diene biosynthetic process|negative regulation of ent-pimara-8(14),15-diene biosynthesis|down-regulation of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene anabolism|down regulation of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene formation|downregulation of ent-pimara-8(14),15-diene synthesis|downregulation of ent-pimara-8(14),15-diene formation http://purl.obolibrary.org/obo/GO_1901543 GO:1901544 biolink:BiologicalProcess positive regulation of ent-pimara-8(14),15-diene biosynthetic process Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process. go-plus.json up regulation of ent-pimara-8(14),15-diene synthesis|activation of ent-pimara-8(14),15-diene synthesis|positive regulation of ent-pimara-8(14),15-diene synthesis|up regulation of ent-pimara-8(14),15-diene formation|activation of ent-pimara-8(14),15-diene formation|positive regulation of ent-pimara-8(14),15-diene formation|upregulation of ent-pimara-8(14),15-diene biosynthesis|upregulation of ent-pimara-8(14),15-diene biosynthetic process|up-regulation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene synthesis|up-regulation of ent-pimara-8(14),15-diene formation|up-regulation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene biosynthetic process|up-regulation of ent-pimara-8(14),15-diene biosynthetic process|upregulation of ent-pimara-8(14),15-diene anabolism|upregulation of ent-pimara-8(14),15-diene synthesis|upregulation of ent-pimara-8(14),15-diene formation|up regulation of ent-pimara-8(14),15-diene anabolism|positive regulation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene anabolism|positive regulation of ent-pimara-8(14),15-diene anabolism|up regulation of ent-pimara-8(14),15-diene biosynthesis|up regulation of ent-pimara-8(14),15-diene biosynthetic process http://purl.obolibrary.org/obo/GO_1901544 GO:1901541 biolink:BiologicalProcess ent-pimara-8(14),15-diene biosynthetic process The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene. go-plus.json ent-pimara-8(14),15-diene anabolism|ent-pimara-8(14),15-diene synthesis|ent-pimara-8(14),15-diene formation|ent-pimara-8(14),15-diene biosynthesis http://purl.obolibrary.org/obo/GO_1901541 GO:1901542 biolink:BiologicalProcess regulation of ent-pimara-8(14),15-diene biosynthetic process Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process. go-plus.json regulation of ent-pimara-8(14),15-diene biosynthesis|regulation of ent-pimara-8(14),15-diene anabolism|regulation of ent-pimara-8(14),15-diene synthesis|regulation of ent-pimara-8(14),15-diene formation http://purl.obolibrary.org/obo/GO_1901542 GO:0060450 biolink:BiologicalProcess positive regulation of hindgut contraction Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0060450 GO:0060451 biolink:BiologicalProcess negative regulation of hindgut contraction Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0060451 GO:1901540 biolink:BiologicalProcess ent-pimara-8(14),15-diene catabolic process The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene. go-plus.json ent-pimara-8(14),15-diene catabolism|ent-pimara-8(14),15-diene degradation|ent-pimara-8(14),15-diene breakdown http://purl.obolibrary.org/obo/GO_1901540 GO:0060452 biolink:BiologicalProcess positive regulation of cardiac muscle contraction Any process that increases the frequency, rate or extent of cardiac muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0060452 GO:0060453 biolink:BiologicalProcess regulation of gastric acid secretion Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. go-plus.json http://purl.obolibrary.org/obo/GO_0060453 GO:0060454 biolink:BiologicalProcess positive regulation of gastric acid secretion Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. go-plus.json http://purl.obolibrary.org/obo/GO_0060454 CHEBI:12755 biolink:ChemicalSubstance indol-3-ylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_12755 GO:0060455 biolink:BiologicalProcess negative regulation of gastric acid secretion Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. go-plus.json http://purl.obolibrary.org/obo/GO_0060455 GO:0060456 biolink:BiologicalProcess positive regulation of digestive system process Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0060456 GO:0060457 biolink:BiologicalProcess negative regulation of digestive system process Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0060457 GO:0060458 biolink:BiologicalProcess right lung development The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. go-plus.json right pulmonary development http://purl.obolibrary.org/obo/GO_0060458 GO:0060459 biolink:BiologicalProcess left lung development The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. go-plus.json left pulmonary development http://purl.obolibrary.org/obo/GO_0060459 OBO:GOCHE_27314 biolink:OntologyClass substance with water-soluble vitamin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_27314 3_STAR GO:1901558 biolink:BiologicalProcess response to metformin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901558 GO:1901559 biolink:BiologicalProcess response to ribavirin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901559 GO:1901556 biolink:BiologicalProcess response to candesartan Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901556 GO:1901557 biolink:BiologicalProcess response to fenofibrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901557 GO:1901554 biolink:BiologicalProcess response to paracetamol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus. go-plus.json response to acetaminophen http://purl.obolibrary.org/obo/GO_1901554 GO:1901555 biolink:BiologicalProcess response to paclitaxel Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901555 GO:1901552 biolink:BiologicalProcess positive regulation of endothelial cell development Any process that activates or increases the frequency, rate or extent of endothelial cell development. go-plus.json activation of endothelial cell development|up regulation of endothelial cell development|upregulation of endothelial cell development|up-regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_1901552 GO:1901553 biolink:BiologicalProcess malonic acid transmembrane transport The directed movement of malonic acid across a membrane. go-plus.json malonic acid membrane transport http://purl.obolibrary.org/obo/GO_1901553 GO:1901550 biolink:BiologicalProcess regulation of endothelial cell development Any process that modulates the frequency, rate or extent of endothelial cell development. go-plus.json http://purl.obolibrary.org/obo/GO_1901550 GO:1901551 biolink:BiologicalProcess negative regulation of endothelial cell development Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. go-plus.json down-regulation of endothelial cell development|downregulation of endothelial cell development|down regulation of endothelial cell development|inhibition of endothelial cell development http://purl.obolibrary.org/obo/GO_1901551 GO:0060440 biolink:BiologicalProcess trachea formation The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. go-plus.json http://purl.obolibrary.org/obo/GO_0060440 GO:0060441 biolink:BiologicalProcess epithelial tube branching involved in lung morphogenesis The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. go-plus.json lung branching morphogenesis http://purl.obolibrary.org/obo/GO_0060441 GO:0060442 biolink:BiologicalProcess branching involved in prostate gland morphogenesis The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. go-plus.json prostate branching|prostate gland branching morphogenesis http://purl.obolibrary.org/obo/GO_0060442 GO:1901560 biolink:BiologicalProcess response to purvalanol A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901560 GO:0060443 biolink:BiologicalProcess mammary gland morphogenesis The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. go-plus.json http://purl.obolibrary.org/obo/GO_0060443 GO:0060444 biolink:BiologicalProcess branching involved in mammary gland duct morphogenesis The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. go-plus.json mammary gland branching morphogenesis http://purl.obolibrary.org/obo/GO_0060444 GO:0060445 biolink:BiologicalProcess branching involved in salivary gland morphogenesis The process in which the branching structure of the salivary gland is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060445 GO:0060446 biolink:BiologicalProcess branching involved in open tracheal system development The process in which the anatomical structures of branches in the open tracheal system are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060446 GO:0060447 biolink:BiologicalProcess bud outgrowth involved in lung branching The process in which a region of the lung epithelium initiates an outgrowth. go-plus.json bud formation involved in lung branching http://purl.obolibrary.org/obo/GO_0060447 GO:0060448 biolink:BiologicalProcess dichotomous subdivision of terminal units involved in lung branching The process in which a lung bud bifurcates. go-plus.json bud bifurcation involved in lung branching http://purl.obolibrary.org/obo/GO_0060448 GO:0060449 biolink:BiologicalProcess bud elongation involved in lung branching The process in which a bud in the lung grows out from the point where it is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0060449 OBA:0005425 biolink:OntologyClass metanephros morphology The morphology of a metanephros. go-plus.json morphology of metanephros http://purl.obolibrary.org/obo/OBA_0005425 UBERON:0013411 biolink:AnatomicalEntity cranial cavity Anatomical cavity that is the lumen of the skull and contains the brain. go-plus.json cavitas cranii|intracranial space|intracranial cavity http://purl.obolibrary.org/obo/UBERON_0013411 CHEBI:131954 biolink:ChemicalSubstance GDP-4-amino-3,4,6-trideoxy-alpha-D-threo-hex-3-enopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_131954 CHEBI:131955 biolink:ChemicalSubstance (5E)-tetradecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_131955 CHEBI:22064 biolink:ChemicalSubstance S-palmitoyl amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22064 CHEBI:61672 biolink:ChemicalSubstance dihydrocarvones go-plus.json http://purl.obolibrary.org/obo/CHEBI_61672 CHEBI:131957 biolink:ChemicalSubstance (5E)-tetradecenoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_131957 chebi_ph7_3 CHEBI:22065 biolink:ChemicalSubstance S-palmitoyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22065 CHEBI:131958 biolink:ChemicalSubstance (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131958 chebi_ph7_3 CHEBI:85640 biolink:ChemicalSubstance cis-3-octenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85640 chebi_ph7_3 CHEBI:61670 biolink:ChemicalSubstance oroxylin A 7-O-beta-D-glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61670 PR:000036929 biolink:Protein polyubiquitin A protein that contains multiple tandem copies of the Ubiquitin (Pfam:PF00240) domain over the entire length of the sequence. go-plus.json fam:polyUb http://purl.obolibrary.org/obo/PR_000036929 CHEBI:131959 biolink:ChemicalSubstance phosphinomethylisomalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131959 CHEBI:85641 biolink:ChemicalSubstance (9E)-12-hydroxyoctadec-9-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85641 CHEBI:22063 biolink:ChemicalSubstance sulfoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22063 CHEBI:85643 biolink:ChemicalSubstance 3'-terminal pUpU(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85643 chebi_ph7_3 CHEBI:85644 biolink:ChemicalSubstance UMP 2',3'-cyclic phosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85644 chebi_ph7_3 CHEBI:61677 biolink:ChemicalSubstance (+)-alpha-santalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61677 chebi_ph7_3 CHEBI:61674 biolink:ChemicalSubstance oroxylin A 7-O-beta-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61674 chebi_ph7_3 CHEBI:131950 biolink:ChemicalSubstance 2-aminobenzoylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131950 CHEBI:116314 biolink:ChemicalSubstance oleamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_116314 chebi_ph7_3 CHEBI:61678 biolink:ChemicalSubstance (+)-endo-beta-bergamotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61678 chebi_ph7_3 CHEBI:131951 biolink:ChemicalSubstance 4-methylpentanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_131951 CHEBI:61679 biolink:ChemicalSubstance (-)-endo-alpha-bergamotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61679 chebi_ph7_3 CHEBI:131952 biolink:ChemicalSubstance 2-aminobenzoylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_131952 CHEBI:46024 biolink:ChemicalSubstance trichostatin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_46024 chebi_ph7_3 CHEBI:71007 biolink:ChemicalSubstance 3-dehydrohexadecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71007 chebi_ph7_3 CHEBI:71008 biolink:ChemicalSubstance 3-dehydrotetradecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71008 chebi_ph7_3 CHEBI:71009 biolink:ChemicalSubstance hexadecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71009 chebi_ph7_3 CHEBI:131964 biolink:ChemicalSubstance (14S,15R)-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131964 chebi_ph7_3 CHEBI:131965 biolink:ChemicalSubstance (14R,15S)-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131965 chebi_ph7_3 CHEBI:61680 biolink:ChemicalSubstance (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61680 chebi_ph7_3 CHEBI:131966 biolink:ChemicalSubstance (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131966 CHEBI:131967 biolink:ChemicalSubstance (4S,5R)-4,5,6-trihydroxy-2-iminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131967 CHEBI:61683 biolink:ChemicalSubstance ubiquinone-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61683 chebi_ph7_3 CHEBI:131969 biolink:ChemicalSubstance (11S,12R)-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131969 chebi_ph7_3 CHEBI:61684 biolink:ChemicalSubstance menaquinol-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61684 chebi_ph7_3 CHEBI:85630 biolink:ChemicalSubstance (Kdo)2-lipid A 1-diphosphate (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85630 CHEBI:61682 biolink:ChemicalSubstance ubiquinol-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61682 chebi_ph7_3 CHEBI:61687 biolink:ChemicalSubstance cis-muurola-3,5-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61687 chebi_ph7_3 CHEBI:61688 biolink:ChemicalSubstance cis-muurola-4(14),5-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61688 chebi_ph7_3 CHEBI:61685 biolink:ChemicalSubstance (+)-cubenene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61685 chebi_ph7_3 CHEBI:85634 biolink:ChemicalSubstance (3R)-3-hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85634 chebi_ph7_3 CHEBI:85635 biolink:ChemicalSubstance (R)-3-hydroxytetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85635 chebi_ph7_3 CHEBI:61686 biolink:ChemicalSubstance (+)-epicubenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61686 chebi_ph7_3 CHEBI:85636 biolink:ChemicalSubstance (2R)-2-hydroxytetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85636 chebi_ph7_3 CHEBI:85637 biolink:ChemicalSubstance (2S)-2-hydroxytetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85637 chebi_ph7_3 CHEBI:131962 biolink:ChemicalSubstance (3E)-octenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131962 chebi_ph7_3 CHEBI:85638 biolink:ChemicalSubstance haloacetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85638 chebi_ph7_3 CHEBI:61689 biolink:ChemicalSubstance amino cyclitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61689 CHEBI:85639 biolink:ChemicalSubstance (9Z)-12-hydroxyoctadec-9-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85639 CHEBI:131963 biolink:ChemicalSubstance 2-(phosphinomethylidene)succinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131963 CHEBI:22046 biolink:ChemicalSubstance S-geranylgeranyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22046 CHEBI:71017 biolink:ChemicalSubstance 1-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71017 CHEBI:155902 biolink:ChemicalSubstance 4-hydroxy-5-(4-hydroxybenzylidene)-3-(4-hydroxyphenyl)furan-2(5H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_155902 CHEBI:155900 biolink:ChemicalSubstance 4-quinolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_155900 chebi_ph7_3 CHEBI:61690 biolink:ChemicalSubstance (+)-alpha-barbatene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61690 chebi_ph7_3 CHEBI:131932 biolink:ChemicalSubstance glycosmisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131932 chebi_ph7_3 CHEBI:131933 biolink:ChemicalSubstance (-)-DCA-CL(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131933 chebi_ph7_3 CHEBI:85660 biolink:ChemicalSubstance N-stearoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85660 CHEBI:131934 biolink:ChemicalSubstance (-)-DCA-CC(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131934 chebi_ph7_3 CHEBI:61694 biolink:ChemicalSubstance L-cysteinylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61694 chebi_ph7_3 CHEBI:131935 biolink:ChemicalSubstance (+)-DCA-CC(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131935 chebi_ph7_3 CHEBI:85661 biolink:ChemicalSubstance 9,10-epoxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85661 CHEBI:61695 biolink:ChemicalSubstance L-prolylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61695 CHEBI:131936 biolink:ChemicalSubstance (+)-DCA-CL(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131936 chebi_ph7_3 CHEBI:22043 biolink:ChemicalSubstance S-farnesyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22043 PR:000036907 biolink:Protein amino acid chain component A fiat object part that is either a modified amino-acid residue or an unmodified amino-acid residue. go-plus.json amino-acid residue http://purl.obolibrary.org/obo/PR_000036907 CHEBI:131937 biolink:ChemicalSubstance ent-glycosmisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131937 chebi_ph7_3 CHEBI:131938 biolink:ChemicalSubstance validoxylamine A 7'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131938 CHEBI:85664 biolink:ChemicalSubstance N,1-dioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85664 CHEBI:61693 biolink:ChemicalSubstance carboxyalkyl phosphate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61693 CHEBI:36687 biolink:ChemicalSubstance acyl chloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36687 CHEBI:61698 biolink:ChemicalSubstance L-ascorbate 6-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61698 chebi_ph7_3 CHEBI:36688 biolink:ChemicalSubstance heterotricyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36688 CHEBI:61699 biolink:ChemicalSubstance (-)-alpha-gurjunene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61699 chebi_ph7_3 CHEBI:85666 biolink:ChemicalSubstance N-arachidonoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85666 CHEBI:36685 biolink:ChemicalSubstance chlorocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36685 CHEBI:61696 biolink:ChemicalSubstance L-prolinylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61696 chebi_ph7_3 CHEBI:85667 biolink:ChemicalSubstance N-icosanoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85667 CHEBI:36686 biolink:ChemicalSubstance chloroarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36686 CHEBI:85668 biolink:ChemicalSubstance N-octadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85668 CHEBI:61697 biolink:ChemicalSubstance fatty acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_61697 CHEBI:85669 biolink:ChemicalSubstance N-icosanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85669 CHEBI:131930 biolink:ChemicalSubstance validamine 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131930 CHEBI:36680 biolink:ChemicalSubstance heteranthrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36680 CHEBI:36683 biolink:ChemicalSubstance organochlorine compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36683 chebi_ph7_3 CHEBI:71010 biolink:ChemicalSubstance tetradecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71010 chebi_ph7_3 CHEBI:71011 biolink:ChemicalSubstance hexadecasphing-4-enine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71011 chebi_ph7_3 CHEBI:36682 biolink:ChemicalSubstance polychlorinated dibenzodioxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36682 CHEBI:131943 biolink:ChemicalSubstance (5E)-tetradecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131943 chebi_ph7_3 CHEBI:131944 biolink:ChemicalSubstance (2E,5E)-tetradecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131944 chebi_ph7_3 CHEBI:131946 biolink:ChemicalSubstance valienone 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131946 CHEBI:85650 biolink:ChemicalSubstance (11E,13Z)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85650 chebi_ph7_3 CHEBI:85651 biolink:ChemicalSubstance (5Z,11E)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85651 chebi_ph7_3 CHEBI:131948 biolink:ChemicalSubstance nocardicin C dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131948 chebi_ph7_3 CHEBI:85652 biolink:ChemicalSubstance (6Z,11E)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85652 chebi_ph7_3 CHEBI:131949 biolink:ChemicalSubstance validone 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131949 CHEBI:85654 biolink:ChemicalSubstance N-palmitoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85654 CHEBI:36699 biolink:ChemicalSubstance corticosteroid hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36699 CHEBI:85655 biolink:ChemicalSubstance (3E)-nonenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85655 chebi_ph7_3 CHEBI:85656 biolink:ChemicalSubstance N-acyllysophosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85656 CHEBI:36697 biolink:ChemicalSubstance 1,2,4,5-tetrachlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36697 chebi_ph7_3 CHEBI:85657 biolink:ChemicalSubstance N-hexadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85657 CHEBI:85658 biolink:ChemicalSubstance N-acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85658 CHEBI:85659 biolink:ChemicalSubstance (3E)-phycoerythrobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85659 CHEBI:131941 biolink:ChemicalSubstance validoxylamine A go-plus.json http://purl.obolibrary.org/obo/CHEBI_131941 CHEBI:71021 biolink:ChemicalSubstance 15-methylhexadecasphing-4-enine-1-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71021 chebi_ph7_3 CHEBI:71036 biolink:ChemicalSubstance 15-methylhexadecasphing-4-enine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71036 CHEBI:131919 biolink:ChemicalSubstance nocardicin G zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131919 chebi_ph7_3 CHEBI:71038 biolink:ChemicalSubstance 3-hydroxyadipyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71038 UBERON:0013455 biolink:AnatomicalEntity spheno-petrosal fissure The sphenopetrosal fissure (or sphenopetrosal suture) is the cranial suture between the sphenoid bone and the petrous portion of the temporal bone. It is in the middle cranial fossa. go-plus.json sphenopetrosal fissure|fissura sphenopetrosa http://purl.obolibrary.org/obo/UBERON_0013455 CHEBI:85680 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85680 chebi_ph7_3 CHEBI:131912 biolink:ChemicalSubstance O-[S-(3-hydroxy-4-methylanthraniloyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_131912 chebi_ph7_3 CHEBI:131913 biolink:ChemicalSubstance O-[S-(3,5-dihydroxy-4-methylanthraniloyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_131913 chebi_ph7_3 CHEBI:22020 biolink:ChemicalSubstance S-(ADP-ribosyl)-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22020 CHEBI:131914 biolink:ChemicalSubstance violacein go-plus.json http://purl.obolibrary.org/obo/CHEBI_131914 chebi_ph7_3 CHEBI:131915 biolink:ChemicalSubstance deoxyviolacein go-plus.json http://purl.obolibrary.org/obo/CHEBI_131915 chebi_ph7_3 CHEBI:131916 biolink:ChemicalSubstance proviolacein go-plus.json http://purl.obolibrary.org/obo/CHEBI_131916 chebi_ph7_3 CHEBI:85687 biolink:ChemicalSubstance diacylglycerol 32:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85687 chebi_ph7_3 CHEBI:85688 biolink:ChemicalSubstance diacylglycerol 32:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85688 chebi_ph7_3 CHEBI:71030 biolink:ChemicalSubstance 15-methylhexadecasphinganine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71030 chebi_ph7_3 CHEBI:71034 biolink:ChemicalSubstance 13-methyltetradecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_71034 chebi_ph7_3 CHEBI:36660 biolink:ChemicalSubstance elemental tellurium go-plus.json http://purl.obolibrary.org/obo/CHEBI_36660 CHEBI:131928 biolink:ChemicalSubstance N-hydroxy-2-methylpropanamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_131928 chebi_ph7_3 CHEBI:71046 biolink:ChemicalSubstance tetradecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71046 CHEBI:131929 biolink:ChemicalSubstance (E)-3-(indol-3-yl)acrylate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131929 chebi_ph7_3 CHEBI:71048 biolink:ChemicalSubstance (S)-dihydrocamalexate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71048 chebi_ph7_3 CHEBI:131920 biolink:ChemicalSubstance isonocardicin C dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131920 chebi_ph7_3 CHEBI:131921 biolink:ChemicalSubstance ethylenediaminetriacetate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131921 chebi_ph7_3 CHEBI:131922 biolink:ChemicalSubstance ethylenediaminediacetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131922 chebi_ph7_3 CHEBI:85670 biolink:ChemicalSubstance N-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85670 CHEBI:85671 biolink:ChemicalSubstance N-arachidonoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85671 CHEBI:85672 biolink:ChemicalSubstance 1-(9Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85672 CHEBI:85674 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85674 chebi_ph7_3 CHEBI:85675 biolink:ChemicalSubstance 3-phenylpropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85675 CHEBI:131927 biolink:ChemicalSubstance dicarboxylic acids and O-substituted derivatives go-plus.json http://purl.obolibrary.org/obo/CHEBI_131927 CHEBI:85676 biolink:ChemicalSubstance 3-phenylpropanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85676 chebi_ph7_3 CHEBI:36674 biolink:ChemicalSubstance phenazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36674 chebi_ph7_3 CHEBI:85678 biolink:ChemicalSubstance (3R)-3-hydroxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85678 CHEBI:85679 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-N-methylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85679 chebi_ph7_3 CHEBI:71041 biolink:ChemicalSubstance 3-dehydrohexadecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71041 CHEBI:71043 biolink:ChemicalSubstance 3-dehydrotetradecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71043 CHEBI:71044 biolink:ChemicalSubstance 2,3-didehydroadipoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71044 chebi_ph7_3 CHEBI:71045 biolink:ChemicalSubstance bisdemethoxycurcumin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71045 chebi_ph7_3 CHEBI:71059 biolink:ChemicalSubstance 15-methylhexadecasphinganine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71059 CHEBI:36641 biolink:ChemicalSubstance 3aH-benzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36641 chebi_ph7_3 OBA:VT0100007 biolink:OntologyClass growth trait The quality of a growth. go-plus.json quality of growth http://purl.obolibrary.org/obo/OBA_VT0100007 CHEBI:36642 biolink:ChemicalSubstance glycohexaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36642 CHEBI:36647 biolink:ChemicalSubstance 2,3-dihydroxy-p-cumate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36647 chebi_ph7_3 GO:0060610 biolink:BiologicalProcess mesenchymal cell differentiation involved in mammary gland development The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts. go-plus.json mammary gland mesenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0060610 GO:0060611 biolink:BiologicalProcess mammary gland fat development The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. go-plus.json http://purl.obolibrary.org/obo/GO_0060611 GO:0060612 biolink:BiologicalProcess adipose tissue development The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. go-plus.json adipogenesis http://purl.obolibrary.org/obo/GO_0060612 OBA:VT0100003 biolink:OntologyClass organism subdivision trait The quality of a organism subdivision. go-plus.json quality of organism subdivision http://purl.obolibrary.org/obo/OBA_VT0100003 GO:0060613 biolink:BiologicalProcess fat pad development The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060613 GO:0060614 biolink:BiologicalProcess negative regulation of mammary gland development in males by androgen receptor signaling pathway Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell. go-plus.json negative regulation of mammary gland development in males by androgen receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060614 GO:0060615 biolink:BiologicalProcess mammary gland bud formation The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0060615 CHEBI:71050 biolink:ChemicalSubstance hexadecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71050 GO:0060616 biolink:BiologicalProcess mammary gland cord formation The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad. go-plus.json mammary gland sprout formation http://purl.obolibrary.org/obo/GO_0060616 CHEBI:71052 biolink:ChemicalSubstance hexadecasphing-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71052 GO:0060617 biolink:BiologicalProcess positive regulation of mammary placode formation by mesenchymal-epithelial signaling Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode. go-plus.json positive regulation of mammary placode formation by mesenchymal-epithelial signalling http://purl.obolibrary.org/obo/GO_0060617 GO:0060618 biolink:BiologicalProcess nipple development The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0060618 GO:0060619 biolink:BiologicalProcess cell migration involved in mammary placode formation The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode. go-plus.json http://purl.obolibrary.org/obo/GO_0060619 CHEBI:36640 biolink:ChemicalSubstance glycoheptaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36640 CHEBI:71056 biolink:ChemicalSubstance 15-methylhexadecasphing-4-enine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71056 CHEBI:131906 biolink:ChemicalSubstance 4-pyranones go-plus.json http://purl.obolibrary.org/obo/CHEBI_131906 CHEBI:131907 biolink:ChemicalSubstance 3-pyrones go-plus.json http://purl.obolibrary.org/obo/CHEBI_131907 CHEBI:85694 biolink:ChemicalSubstance diacylglycerol 34:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85694 chebi_ph7_3 CHEBI:36654 biolink:ChemicalSubstance 2,3-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36654 chebi_ph7_3 CHEBI:36655 biolink:ChemicalSubstance glyoxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36655 chebi_ph7_3 CHEBI:36658 biolink:ChemicalSubstance 6-methylsalicylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36658 chebi_ph7_3 CHEBI:36659 biolink:ChemicalSubstance 3-(4-hydroxyphenyl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36659 chebi_ph7_3 GO:0060600 biolink:BiologicalProcess dichotomous subdivision of an epithelial terminal unit The process in which an epithelial cord, rod or tube bifurcates at its end. go-plus.json primary branching of an epithelium http://purl.obolibrary.org/obo/GO_0060600 GO:0060601 biolink:BiologicalProcess lateral sprouting from an epithelium The process in which a branch forms along the side of an epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0060601 CHEBI:36656 biolink:ChemicalSubstance phenylglyoxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36656 chebi_ph7_3 GO:0060602 biolink:BiologicalProcess branch elongation of an epithelium The growth process in which a branch increases in length from its base to its tip. go-plus.json http://purl.obolibrary.org/obo/GO_0060602 GO:0060603 biolink:BiologicalProcess mammary gland duct morphogenesis The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. go-plus.json http://purl.obolibrary.org/obo/GO_0060603 GO:0060604 biolink:BiologicalProcess mammary gland duct cavitation Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod. go-plus.json milk duct cavitation http://purl.obolibrary.org/obo/GO_0060604 GO:0060605 biolink:BiologicalProcess tube lumen cavitation The formation of a lumen by hollowing out a solid rod or cord. go-plus.json http://purl.obolibrary.org/obo/GO_0060605 GO:0060606 biolink:BiologicalProcess tube closure Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. go-plus.json http://purl.obolibrary.org/obo/GO_0060606 CHEBI:71063 biolink:ChemicalSubstance N-retinylidenephosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71063 GO:0060607 biolink:BiologicalProcess cell-cell adhesion involved in sealing an epithelial fold The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube. go-plus.json http://purl.obolibrary.org/obo/GO_0060607 GO:0060608 biolink:BiologicalProcess cell-cell adhesion involved in neural tube closure The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0060608 GO:0060609 biolink:BiologicalProcess apoptotic process involved in tube lumen cavitation Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube. go-plus.json apoptosis involved in tube lumen cavitation http://purl.obolibrary.org/obo/GO_0060609 GO:0035669 biolink:BiologicalProcess TRAM-dependent toll-like receptor 4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. go-plus.json TRAM-dependent TLR4 signaling pathway|TRAM-dependent toll-like receptor 4 signalling pathway http://purl.obolibrary.org/obo/GO_0035669 GO:0035661 biolink:BiologicalProcess MyD88-dependent toll-like receptor 2 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response. go-plus.json MyD88-dependent TLR2 signaling pathway|MyD88-dependent toll-like receptor 2 signalling pathway http://purl.obolibrary.org/obo/GO_0035661 GO:0035662 biolink:MolecularActivity Toll-like receptor 4 binding Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response. go-plus.json TLR4 binding http://purl.obolibrary.org/obo/GO_0035662 GO:0035663 biolink:MolecularActivity Toll-like receptor 2 binding Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response. go-plus.json TLR2 binding http://purl.obolibrary.org/obo/GO_0035663 GO:0035664 biolink:BiologicalProcess TIRAP-dependent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go-plus.json MAL-dependent toll-like receptor signaling pathway|TIRAP-dependent TLR signaling pathway|MyD88 adapter-like dependent toll-like receptor signaling pathway|TIRAP-dependent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035664 GO:0035665 biolink:BiologicalProcess TIRAP-dependent toll-like receptor 4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. go-plus.json MyD88 adapter-like dependent toll-like receptor 4 signaling pathway|TIRAP-dependent TLR4 signaling pathway|TIRAP-dependent toll-like receptor 4 signalling pathway|MAL-dependent toll-like receptor 4 signaling pathway http://purl.obolibrary.org/obo/GO_0035665 GO:0035666 biolink:BiologicalProcess TRIF-dependent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go-plus.json TRIF-dependent TLR signaling pathway|TRIF-dependent toll-like receptor signalling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR signaling pathway http://purl.obolibrary.org/obo/GO_0035666 GO:0035667 biolink:BiologicalProcess TRIF-dependent toll-like receptor 4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. go-plus.json TRIF-dependent toll-like receptor 4 signalling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway|TRIF-dependent TLR4 signaling pathway http://purl.obolibrary.org/obo/GO_0035667 GO:0035668 biolink:BiologicalProcess TRAM-dependent toll-like receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. go-plus.json TRAM-dependent TLR signaling pathway|TRAM-dependent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035668 GO:0035660 biolink:BiologicalProcess MyD88-dependent toll-like receptor 4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. go-plus.json MyD88-dependent toll-like receptor 4 signalling pathway|MyD88-dependent TLR4 signaling pathway http://purl.obolibrary.org/obo/GO_0035660 GO:0035658 biolink:CellularComponent Mon1-Ccz1 complex A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p. go-plus.json http://purl.obolibrary.org/obo/GO_0035658 GO:0035659 biolink:BiologicalProcess Wnt signaling pathway involved in wound healing, spreading of epidermal cells The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis. go-plus.json Wnt receptor signalling pathway involved in wound healing, spreading of epidermal cells|Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells|Wnt-activated signaling pathway involved in wound healing, spreading of epidermal cells http://purl.obolibrary.org/obo/GO_0035659 GO:0035650 biolink:MolecularActivity AP-1 adaptor complex binding Binding to an AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). go-plus.json http://purl.obolibrary.org/obo/GO_0035650 GO:0035651 biolink:MolecularActivity AP-3 adaptor complex binding Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B). go-plus.json http://purl.obolibrary.org/obo/GO_0035651 GO:0035652 biolink:BiologicalProcess clathrin-coated vesicle cargo loading Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle. go-plus.json cargo loading into clathrin-coated vesicle http://purl.obolibrary.org/obo/GO_0035652 GO:0035653 biolink:BiologicalProcess clathrin-coated vesicle cargo loading, AP-1-mediated Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking. go-plus.json cargo loading into clathrin-coated vesicle, AP-1-mediated http://purl.obolibrary.org/obo/GO_0035653 GO:0035654 biolink:BiologicalProcess clathrin-coated vesicle cargo loading, AP-3-mediated Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle. go-plus.json cargo loading into clathrin-coated vesicle, AP-3-mediated http://purl.obolibrary.org/obo/GO_0035654 GO:0035655 biolink:BiologicalProcess interleukin-18-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-18-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0035655 GO:0035656 biolink:MolecularActivity obsolete kinesin-associated melanosomal adaptor activity OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes. go-plus.json kinesin-melanosome adaptor activity http://purl.obolibrary.org/obo/GO_0035656 GO:0035657 biolink:CellularComponent eRF1 methyltransferase complex A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p. go-plus.json eRF1 MTase complex http://purl.obolibrary.org/obo/GO_0035657 GO:0035647 biolink:MolecularActivity 3-oxo-delta(4,5)-steroid 5-beta-reductase activity Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+). go-plus.json 3-oxo-delta4,5-steroid 5beta-reductase http://purl.obolibrary.org/obo/GO_0035647 GO:0035648 biolink:BiologicalProcess circadian mating behavior The fluctuation in mating behavior that occurs over an approximately 24 hour cycle. go-plus.json circadian mating rhythm|circadian mating behaviour http://purl.obolibrary.org/obo/GO_0035648 GO:0035649 biolink:CellularComponent Nrd1 complex A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p. go-plus.json http://purl.obolibrary.org/obo/GO_0035649 CHEBI:61610 biolink:ChemicalSubstance beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61610 chebi_ph7_3 GO:0035640 biolink:BiologicalProcess exploration behavior The specific behavior of an organism in response to a novel environment or stimulus. go-plus.json exploratory behavior|exploratory behaviour|exploration behaviour|open-field behavior http://purl.obolibrary.org/obo/GO_0035640 GO:0035641 biolink:BiologicalProcess locomotory exploration behavior The specific movement from place to place of an organism in response to a novel environment. go-plus.json http://purl.obolibrary.org/obo/GO_0035641 GO:0035642 biolink:MolecularActivity histone methyltransferase activity (H3-R17 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3. go-plus.json histone-arginine N-methyltransferase activity (H3-R17 specific)|histone methylase activity (H3-R17 specific) http://purl.obolibrary.org/obo/GO_0035642 GO:0035643 biolink:MolecularActivity L-DOPA receptor activity Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine. go-plus.json L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity|L-dopa receptor activity http://purl.obolibrary.org/obo/GO_0035643 GO:0035644 biolink:BiologicalProcess phosphoanandamide dephosphorylation The process of removing one or more phosphate groups from a phosphorylated anandamide. go-plus.json http://purl.obolibrary.org/obo/GO_0035644 GO:0035645 biolink:BiologicalProcess enteric smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine. go-plus.json intestinal smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0035645 GO:0035646 biolink:BiologicalProcess endosome to melanosome transport The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0035646 GO:0035636 biolink:BiologicalProcess obsolete multi-organism signaling OBSOLETE. The transfer of information between living organisms. go-plus.json signaling between organisms|pheromone signaling|multi-organism signalling|signaling with other organism http://purl.obolibrary.org/obo/GO_0035636 GO:0035637 biolink:BiologicalProcess multicellular organismal signaling The transfer of information occurring at the level of a multicellular organism. go-plus.json multicellular organismal signalling http://purl.obolibrary.org/obo/GO_0035637 GO:0035638 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035638 GO:0035639 biolink:MolecularActivity purine ribonucleoside triphosphate binding Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json purine NTP binding http://purl.obolibrary.org/obo/GO_0035639 GO:0035630 biolink:BiologicalProcess bone mineralization involved in bone maturation The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0035630 GO:0035631 biolink:CellularComponent CD40 receptor complex A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0035631 GO:0035632 biolink:CellularComponent mitochondrial prohibitin complex A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death. go-plus.json mitochondrial inner membrane prohibitin complex http://purl.obolibrary.org/obo/GO_0035632 GO:0035633 biolink:BiologicalProcess maintenance of blood-brain barrier Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation. go-plus.json maintenance of BBB|maintenance of blood/brain barrier http://purl.obolibrary.org/obo/GO_0035633 GO:0035634 biolink:BiologicalProcess response to stilbenoid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. go-plus.json http://purl.obolibrary.org/obo/GO_0035634 goslim_chembl CHEBI:61623 biolink:ChemicalSubstance fluoroacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61623 chebi_ph7_3 GO:0035635 biolink:BiologicalProcess entry of bacterium into host cell The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json invasion of bacteria into host cell|bacterial entry into host cell http://purl.obolibrary.org/obo/GO_0035635 GO:0035625 biolink:BiologicalProcess obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway OBSOLETE. The process in which an epidermal growth factor-activated receptor is activated via signaling events from a consequence of a G protein-coupled . This is an example of cross-talk between the EGF and GPCR signaling pathways. go-plus.json EGFR transactivation by GPCR|EGFR transactivation upon GPCR stimulation|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035625 GO:0035626 biolink:BiologicalProcess juvenile hormone mediated signaling pathway A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity. go-plus.json juvenile hormone-mediated signaling pathway|juvenile hormone mediated signalling pathway http://purl.obolibrary.org/obo/GO_0035626 GO:0035627 biolink:BiologicalProcess ceramide transport The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid. go-plus.json http://purl.obolibrary.org/obo/GO_0035627 GO:0035628 biolink:BiologicalProcess cystic duct development The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct. go-plus.json http://purl.obolibrary.org/obo/GO_0035628 GO:0035629 biolink:BiologicalProcess N-terminal protein amino acid N-linked glycosylation Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0035629 CHEBI:46077 biolink:ChemicalSubstance 4H-1,2,4-triazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_46077 chebi_ph7_3 CHEBI:131990 biolink:ChemicalSubstance (2E,5Z)-octadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131990 chebi_ph7_3 GO:0035620 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035620 CHEBI:85602 biolink:ChemicalSubstance N-carbamoyl-D-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85602 chebi_ph7_3 CHEBI:61631 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61631 chebi_ph7_3 CHEBI:131992 biolink:ChemicalSubstance 5,6-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131992 chebi_ph7_3 GO:0035621 biolink:BiologicalProcess ER to Golgi ceramide transport The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid. go-plus.json ER to Golgi ceramide translocation|endoplasmic reticulum to Golgi ceramide transport|non-vesicular ceramide trafficking http://purl.obolibrary.org/obo/GO_0035621 CHEBI:85603 biolink:ChemicalSubstance 1-tuberculosinyladenosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85603 chebi_ph7_3 CHEBI:131993 biolink:ChemicalSubstance lysophosphatidylethanolamine 22:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_131993 GO:0035622 biolink:BiologicalProcess intrahepatic bile duct development The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). go-plus.json IHBD development|intrahepatic biliary duct development http://purl.obolibrary.org/obo/GO_0035622 GO:0035623 biolink:BiologicalProcess renal glucose absorption A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. go-plus.json nephron glucose absorption|glucose reabsorption http://purl.obolibrary.org/obo/GO_0035623 GO:0035624 biolink:BiologicalProcess receptor transactivation The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer. go-plus.json http://purl.obolibrary.org/obo/GO_0035624 CHEBI:46081 biolink:ChemicalSubstance fluconazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_46081 chebi_ph7_3 GO:0035614 biolink:MolecularActivity snRNA stem-loop binding Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop. go-plus.json snRNA hairpin binding|small nuclear RNA stem-loop binding|snRNA hairpin loop binding http://purl.obolibrary.org/obo/GO_0035614 GO:0035615 biolink:MolecularActivity clathrin adaptor activity Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles. go-plus.json clathrin-associated adaptor activity http://purl.obolibrary.org/obo/GO_0035615 GO:0035616 biolink:BiologicalProcess histone H2B conserved C-terminal lysine deubiquitination A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals. go-plus.json budding yeast H2B K123 deubiquitination|mammalian H2B K120 deubiquitination|fission yeast H2B K119 deubiquitination http://purl.obolibrary.org/obo/GO_0035616 GO:0035617 biolink:BiologicalProcess stress granule disassembly The disaggregation of a stress granule into its constituent protein and RNA parts. go-plus.json SG disassembly http://purl.obolibrary.org/obo/GO_0035617 GO:0035618 biolink:CellularComponent root hair A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0035618 GO:0035619 biolink:CellularComponent root hair tip The tip portion of an outgrowth of a root epidermal cell. go-plus.json root hair cell tip http://purl.obolibrary.org/obo/GO_0035619 GO:0035610 biolink:BiologicalProcess protein side chain deglutamylation The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation. go-plus.json shortening of glutamate side chain|removal of posttranslational polyglutamylation http://purl.obolibrary.org/obo/GO_0035610 GO:0035611 biolink:BiologicalProcess protein branching point deglutamylation The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue. go-plus.json http://purl.obolibrary.org/obo/GO_0035611 GO:0035612 biolink:MolecularActivity AP-2 adaptor complex binding Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). go-plus.json AP-2 clathrin adaptor complex binding http://purl.obolibrary.org/obo/GO_0035612 CHEBI:61645 biolink:ChemicalSubstance L-seryl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_61645 GO:0035613 biolink:MolecularActivity RNA stem-loop binding Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop. go-plus.json RNA hairpin binding|RNA hairpin loop binding http://purl.obolibrary.org/obo/GO_0035613 CHEBI:61646 biolink:ChemicalSubstance fluoroacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61646 GO:0035603 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in hemopoiesis The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis. go-plus.json fibroblast growth factor receptor signaling pathway involved in hematopoiesis|FGF receptor signaling pathway involved in hematopoiesis|FGFR signaling pathway involved in hematopoiesis|fibroblast growth factor receptor signalling pathway involved in hemopoiesis http://purl.obolibrary.org/obo/GO_0035603 CHEBI:131975 biolink:ChemicalSubstance (8R,9S)-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131975 chebi_ph7_3 GO:0035604 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow. go-plus.json fibroblast growth factor receptor signalling pathway involved in positive regulation of cell proliferation in bone marrow|FGFR signaling pathway involved in positive regulation of cell proliferation in bone marrow|FGF receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow http://purl.obolibrary.org/obo/GO_0035604 CHEBI:46050 biolink:ChemicalSubstance docosane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46050 chebi_ph7_3 GO:0035605 biolink:MolecularActivity peptidyl-cysteine S-nitrosylase activity Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein. go-plus.json protein nitrosylase activity|S-nitrosylase activity http://purl.obolibrary.org/obo/GO_0035605 CHEBI:22080 biolink:ChemicalSubstance TDP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_22080 GO:0035606 biolink:BiologicalProcess peptidyl-cysteine S-trans-nitrosylation Transfer of a nitric oxide (NO) group from one cysteine residue to another. go-plus.json S-transnitrosylation|protein-to-protein transnitrosylation|cysteine-to-cysteine transnitrosylation|cysteine to cysteine nitrosylation http://purl.obolibrary.org/obo/GO_0035606 CHEBI:131978 biolink:ChemicalSubstance (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131978 chebi_ph7_3 GO:0035607 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state. go-plus.json FGF receptor signaling pathway involved in orbitofrontal cortex development|fibroblast growth factor receptor signalling pathway involved in orbitofrontal cortex development|FGFR signaling pathway involved in orbitofrontal cortex development http://purl.obolibrary.org/obo/GO_0035607 CHEBI:46053 biolink:ChemicalSubstance 2,4,6-trinitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_46053 chebi_ph7_3 CHEBI:131979 biolink:ChemicalSubstance 5,10-dihydrophenazine-1,6-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131979 chebi_ph7_3 GO:0035608 biolink:BiologicalProcess protein deglutamylation The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation. go-plus.json protein amino acid deglutamylation http://purl.obolibrary.org/obo/GO_0035608 GO:0035609 biolink:BiologicalProcess C-terminal protein deglutamylation The removal of a C-terminal, gene-encoded glutamate residue from a protein. go-plus.json protein primary sequence deglutamylation http://purl.obolibrary.org/obo/GO_0035609 CHEBI:85620 biolink:ChemicalSubstance Fe4S3 iron-sulfur cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_85620 CHEBI:85621 biolink:ChemicalSubstance L-3-oxoalanine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85621 chebi_ph7_3 CHEBI:61655 biolink:ChemicalSubstance steroid saponin go-plus.json http://purl.obolibrary.org/obo/CHEBI_61655 CHEBI:131970 biolink:ChemicalSubstance (11R,12S)-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131970 chebi_ph7_3 CHEBI:131971 biolink:ChemicalSubstance (1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131971 chebi_ph7_3 GO:0035600 biolink:BiologicalProcess tRNA methylthiolation The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035600 GO:0035601 biolink:BiologicalProcess protein deacylation The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid. go-plus.json protein amino acid deacylation http://purl.obolibrary.org/obo/GO_0035601 CHEBI:131973 biolink:ChemicalSubstance (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131973 chebi_ph7_3 GO:0035602 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow. go-plus.json FGFR signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow|fibroblast growth factor receptor signalling pathway involved in negative regulation of apoptotic process in bone marrow|FGF receptor signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow http://purl.obolibrary.org/obo/GO_0035602 CHEBI:131974 biolink:ChemicalSubstance (8S,9R)-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131974 chebi_ph7_3 CHEBI:22099 biolink:ChemicalSubstance UDP-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22099 CHEBI:131986 biolink:ChemicalSubstance 1-docosahexaenoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_131986 chebi_ph7_3 CHEBI:131987 biolink:ChemicalSubstance 2-docosahexaenoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_131987 chebi_ph7_3 CHEBI:61661 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61661 CHEBI:61662 biolink:ChemicalSubstance 2'-deoxyribonucleoside triphosphate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61662 CHEBI:61660 biolink:ChemicalSubstance organic sulfamate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61660 chebi_ph7_3 CHEBI:61665 biolink:ChemicalSubstance 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61665 chebi_ph7_3 CHEBI:61666 biolink:ChemicalSubstance amidobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61666 CHEBI:61663 biolink:ChemicalSubstance alpha-D-Manp-(1->3)-alpha-D-Manp go-plus.json http://purl.obolibrary.org/obo/CHEBI_61663 chebi_ph7_3 CHEBI:131980 biolink:ChemicalSubstance phenazine-1,6-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131980 chebi_ph7_3 CHEBI:131981 biolink:ChemicalSubstance (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131981 chebi_ph7_3 CHEBI:61664 biolink:ChemicalSubstance 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61664 CHEBI:61669 biolink:ChemicalSubstance 2-methylbutanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_61669 chebi_ph7_3 CHEBI:85614 biolink:ChemicalSubstance neopikromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85614 CHEBI:61667 biolink:ChemicalSubstance D-hexopyranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61667 CHEBI:61668 biolink:ChemicalSubstance oroxylin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_61668 GO:1901448 biolink:BiologicalProcess regulation of response to butan-1-ol Any process that modulates the frequency, rate or extent of response to butan-1-ol. go-plus.json http://purl.obolibrary.org/obo/GO_1901448 GO:1901449 biolink:BiologicalProcess negative regulation of response to butan-1-ol Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol. go-plus.json down-regulation of response to butan-1-ol|downregulation of response to butan-1-ol|down regulation of response to butan-1-ol|inhibition of response to butan-1-ol http://purl.obolibrary.org/obo/GO_1901449 GO:1901446 biolink:BiologicalProcess negative regulation of response to propan-1-ol Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol. go-plus.json downregulation of response to propan-1-ol|down-regulation of response to propan-1-ol|inhibition of response to propan-1-ol|down regulation of response to propan-1-ol http://purl.obolibrary.org/obo/GO_1901446 GO:1901447 biolink:BiologicalProcess positive regulation of response to propan-1-ol Any process that activates or increases the frequency, rate or extent of response to propan-1-ol. go-plus.json up regulation of response to propan-1-ol|activation of response to propan-1-ol|up-regulation of response to propan-1-ol|upregulation of response to propan-1-ol http://purl.obolibrary.org/obo/GO_1901447 GO:1901444 biolink:BiologicalProcess positive regulation of response to furfural Any process that activates or increases the frequency, rate or extent of response to furfural. go-plus.json up-regulation of response to furfural|activation of response to furfural|up regulation of response to furfural|upregulation of response to furfural http://purl.obolibrary.org/obo/GO_1901444 GO:0060590 biolink:MolecularActivity ATPase regulator activity Binds to and modulates the activity of an ATP hydrolysis activity. go-plus.json ATP hydrolysis regulator activity http://purl.obolibrary.org/obo/GO_0060590 GO:1901445 biolink:BiologicalProcess regulation of response to propan-1-ol Any process that modulates the frequency, rate or extent of response to propan-1-ol. go-plus.json http://purl.obolibrary.org/obo/GO_1901445 GO:1901442 biolink:BiologicalProcess regulation of response to furfural Any process that modulates the frequency, rate or extent of response to furfural. go-plus.json http://purl.obolibrary.org/obo/GO_1901442 GO:0060591 biolink:BiologicalProcess chondroblast differentiation The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. go-plus.json chondrocyte progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0060591 GO:0060592 biolink:BiologicalProcess mammary gland formation The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. go-plus.json mammary placode formation|mammary line formation|mammary bud formation|mammary sprout formation http://purl.obolibrary.org/obo/GO_0060592 GO:1901443 biolink:BiologicalProcess negative regulation of response to furfural Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural. go-plus.json down-regulation of response to furfural|downregulation of response to furfural|down regulation of response to furfural|inhibition of response to furfural http://purl.obolibrary.org/obo/GO_1901443 GO:1901440 biolink:BiologicalProcess poly(hydroxyalkanoate) metabolic process The chemical reactions and pathways involving poly(hydroxyalkanoate). go-plus.json poly(hydroxyalkanoate) metabolism http://purl.obolibrary.org/obo/GO_1901440 GO:0060593 biolink:BiologicalProcess Wnt signaling pathway involved in mammary gland specification The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes. go-plus.json Wnt receptor signalling pathway involved in mammary gland specification|Wnt receptor signaling pathway involved in mammary gland specification|Wnt-activated signaling pathway involved in mammary gland specification http://purl.obolibrary.org/obo/GO_0060593 GO:0060594 biolink:BiologicalProcess mammary gland specification The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes. go-plus.json mammary line specification http://purl.obolibrary.org/obo/GO_0060594 GO:1901441 biolink:BiologicalProcess poly(hydroxyalkanoate) biosynthetic process The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate). go-plus.json poly(hydroxyalkanoate) anabolism|poly(hydroxyalkanoate) synthesis|poly(hydroxyalkanoate) formation|poly(hydroxyalkanoate) biosynthesis http://purl.obolibrary.org/obo/GO_1901441 GO:0060595 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in mammary gland specification The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes. go-plus.json fibroblast growth factor receptor signalling pathway involved in mammary gland specification http://purl.obolibrary.org/obo/GO_0060595 GO:0060596 biolink:BiologicalProcess mammary placode formation The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. go-plus.json http://purl.obolibrary.org/obo/GO_0060596 GO:1901450 biolink:BiologicalProcess positive regulation of response to butan-1-ol Any process that activates or increases the frequency, rate or extent of response to butan-1-ol. go-plus.json up-regulation of response to butan-1-ol|activation of response to butan-1-ol|up regulation of response to butan-1-ol|upregulation of response to butan-1-ol http://purl.obolibrary.org/obo/GO_1901450 GO:0060597 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in mammary gland formation OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060597 GO:0060598 biolink:BiologicalProcess dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis The process in which the terminal end of a mammary duct bifurcates. go-plus.json primary mammary duct branching http://purl.obolibrary.org/obo/GO_0060598 GO:0060599 biolink:BiologicalProcess lateral sprouting involved in mammary gland duct morphogenesis The process in which a branch forms along the side of a mammary duct. go-plus.json mammary gland duct secondary branching http://purl.obolibrary.org/obo/GO_0060599 GO:1901459 biolink:BiologicalProcess positive regulation of response to acetate Any process that activates or increases the frequency, rate or extent of response to acetate. go-plus.json up regulation of response to acetate|activation of response to acetate|up-regulation of response to acetate|upregulation of response to acetate http://purl.obolibrary.org/obo/GO_1901459 GO:1901457 biolink:BiologicalProcess regulation of response to acetate Any process that modulates the frequency, rate or extent of response to acetate. go-plus.json http://purl.obolibrary.org/obo/GO_1901457 GO:1901458 biolink:BiologicalProcess negative regulation of response to acetate Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate. go-plus.json down regulation of response to acetate|downregulation of response to acetate|down-regulation of response to acetate|inhibition of response to acetate http://purl.obolibrary.org/obo/GO_1901458 GO:1901455 biolink:BiologicalProcess negative regulation of response to toluene Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene. go-plus.json down regulation of response to toluene|downregulation of response to toluene|down-regulation of response to toluene|inhibition of response to toluene http://purl.obolibrary.org/obo/GO_1901455 GO:1901456 biolink:BiologicalProcess positive regulation of response to toluene Any process that activates or increases the frequency, rate or extent of response to toluene. go-plus.json upregulation of response to toluene|up regulation of response to toluene|activation of response to toluene|up-regulation of response to toluene http://purl.obolibrary.org/obo/GO_1901456 GO:0060580 biolink:BiologicalProcess ventral spinal cord interneuron fate determination The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. go-plus.json http://purl.obolibrary.org/obo/GO_0060580 GO:1901453 biolink:BiologicalProcess positive regulation of response to benzene Any process that activates or increases the frequency, rate or extent of response to benzene. go-plus.json up-regulation of response to benzene|upregulation of response to benzene|up regulation of response to benzene|activation of response to benzene http://purl.obolibrary.org/obo/GO_1901453 GO:0060581 biolink:BiologicalProcess cell fate commitment involved in pattern specification The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. go-plus.json http://purl.obolibrary.org/obo/GO_0060581 GO:1901454 biolink:BiologicalProcess regulation of response to toluene Any process that modulates the frequency, rate or extent of response to toluene. go-plus.json http://purl.obolibrary.org/obo/GO_1901454 GO:1901451 biolink:BiologicalProcess regulation of response to benzene Any process that modulates the frequency, rate or extent of response to benzene. go-plus.json http://purl.obolibrary.org/obo/GO_1901451 GO:0060582 biolink:BiologicalProcess cell fate determination involved in pattern specification A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060582 GO:0060583 biolink:BiologicalProcess regulation of actin cortical patch localization Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells. go-plus.json regulation of actin cortical patch localisation http://purl.obolibrary.org/obo/GO_0060583 GO:1901452 biolink:BiologicalProcess negative regulation of response to benzene Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene. go-plus.json inhibition of response to benzene|down regulation of response to benzene|downregulation of response to benzene|down-regulation of response to benzene http://purl.obolibrary.org/obo/GO_1901452 GO:1901460 biolink:BiologicalProcess regulation of response to formic acid Any process that modulates the frequency, rate or extent of response to formic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1901460 GO:0060584 biolink:BiologicalProcess regulation of prostaglandin-endoperoxide synthase activity Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. go-plus.json regulation of (PG)H synthase activity|regulation of fatty acid cyclooxygenase activity|regulation of prostaglandin synthetase activity|regulation of PG synthetase activity http://purl.obolibrary.org/obo/GO_0060584 GO:1901461 biolink:BiologicalProcess negative regulation of response to formic acid Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid. go-plus.json inhibition of response to formic acid|down regulation of response to formic acid|downregulation of response to formic acid|down-regulation of response to formic acid http://purl.obolibrary.org/obo/GO_1901461 GO:0060585 biolink:BiologicalProcess positive regulation of prostaglandin-endoperoxide synthase activity Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. go-plus.json positive regulation of fatty acid cyclooxygenase activity|positive regulation of (PG)H synthase activity|positive regulation of PG synthetase activity|positive regulation of prostaglandin synthetase activity http://purl.obolibrary.org/obo/GO_0060585 GO:0060586 biolink:BiologicalProcess multicellular organismal iron ion homeostasis Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0060586 GO:0060587 biolink:BiologicalProcess regulation of lipoprotein lipid oxidation Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group. go-plus.json http://purl.obolibrary.org/obo/GO_0060587 GO:0060588 biolink:BiologicalProcess negative regulation of lipoprotein lipid oxidation Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group. go-plus.json http://purl.obolibrary.org/obo/GO_0060588 GO:0060589 biolink:MolecularActivity nucleoside-triphosphatase regulator activity Binds to and modulates the activity of an NTPase. go-plus.json NTPase regulator activity http://purl.obolibrary.org/obo/GO_0060589 GO:1901468 biolink:BiologicalProcess positive regulation of ferulate catabolic process Any process that activates or increases the frequency, rate or extent of ferulate catabolic process. go-plus.json upregulation of ferulate breakdown|up-regulation of ferulate degradation|upregulation of ferulate catabolic process|up regulation of ferulate catabolism|up-regulation of ferulate breakdown|activation of ferulate degradation|positive regulation of ferulate catabolism|up-regulation of ferulate catabolic process|activation of ferulate catabolic process|activation of ferulate catabolism|positive regulation of ferulate degradation|activation of ferulate breakdown|up regulation of ferulate degradation|positive regulation of ferulate breakdown|up-regulation of ferulate catabolism|up regulation of ferulate breakdown|up regulation of ferulate catabolic process|upregulation of ferulate degradation|upregulation of ferulate catabolism http://purl.obolibrary.org/obo/GO_1901468 GO:1901469 biolink:BiologicalProcess regulation of syringal lignin catabolic process Any process that modulates the frequency, rate or extent of syringal lignin catabolic process. go-plus.json regulation of syringal lignin breakdown|regulation of S-lignin catabolic process|regulation of syringal lignin degradation|regulation of syringal lignin catabolism http://purl.obolibrary.org/obo/GO_1901469 GO:1901466 biolink:BiologicalProcess regulation of ferulate catabolic process Any process that modulates the frequency, rate or extent of ferulate catabolic process. go-plus.json regulation of ferulate catabolism|regulation of ferulate degradation|regulation of ferulate breakdown http://purl.obolibrary.org/obo/GO_1901466 GO:1901467 biolink:BiologicalProcess negative regulation of ferulate catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process. go-plus.json inhibition of ferulate degradation|down regulation of ferulate catabolic process|down regulation of ferulate catabolism|inhibition of ferulate catabolic process|inhibition of ferulate breakdown|downregulation of ferulate catabolism|negative regulation of ferulate degradation|down-regulation of ferulate degradation|down-regulation of ferulate catabolism|negative regulation of ferulate catabolism|negative regulation of ferulate breakdown|down-regulation of ferulate breakdown|downregulation of ferulate degradation|down-regulation of ferulate catabolic process|down regulation of ferulate degradation|downregulation of ferulate breakdown|inhibition of ferulate catabolism|downregulation of ferulate catabolic process|down regulation of ferulate breakdown http://purl.obolibrary.org/obo/GO_1901467 GO:1901464 biolink:BiologicalProcess negative regulation of tetrapyrrole biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process. go-plus.json down regulation of tetrapyrrole anabolism|downregulation of tetrapyrrole synthesis|inhibition of tetrapyrrole biosynthesis|downregulation of tetrapyrrole formation|down regulation of tetrapyrrole synthesis|down regulation of tetrapyrrole formation|inhibition of tetrapyrrole anabolism|down regulation of tetrapyrrole biosynthetic process|down regulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole synthesis|downregulation of tetrapyrrole biosynthetic process|downregulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole formation|down-regulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole biosynthesis|down-regulation of tetrapyrrole biosynthetic process|down-regulation of tetrapyrrole biosynthesis|down-regulation of tetrapyrrole synthesis|negative regulation of tetrapyrrole synthesis|down-regulation of tetrapyrrole formation|negative regulation of tetrapyrrole formation|inhibition of tetrapyrrole biosynthetic process|downregulation of tetrapyrrole anabolism http://purl.obolibrary.org/obo/GO_1901464 GO:1901465 biolink:BiologicalProcess positive regulation of tetrapyrrole biosynthetic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process. go-plus.json up regulation of tetrapyrrole formation|upregulation of tetrapyrrole anabolism|upregulation of tetrapyrrole biosynthetic process|upregulation of tetrapyrrole biosynthesis|upregulation of tetrapyrrole synthesis|upregulation of tetrapyrrole formation|up-regulation of tetrapyrrole anabolism|up regulation of tetrapyrrole biosynthesis|up regulation of tetrapyrrole biosynthetic process|up-regulation of tetrapyrrole synthesis|activation of tetrapyrrole biosynthetic process|positive regulation of tetrapyrrole biosynthesis|activation of tetrapyrrole anabolism|up-regulation of tetrapyrrole formation|activation of tetrapyrrole biosynthesis|activation of tetrapyrrole synthesis|positive regulation of tetrapyrrole anabolism|up regulation of tetrapyrrole anabolism|activation of tetrapyrrole formation|positive regulation of tetrapyrrole synthesis|up-regulation of tetrapyrrole biosynthetic process|up-regulation of tetrapyrrole biosynthesis|up regulation of tetrapyrrole synthesis|positive regulation of tetrapyrrole formation http://purl.obolibrary.org/obo/GO_1901465 GO:1901462 biolink:BiologicalProcess positive regulation of response to formic acid Any process that activates or increases the frequency, rate or extent of response to formic acid. go-plus.json up-regulation of response to formic acid|upregulation of response to formic acid|up regulation of response to formic acid|activation of response to formic acid http://purl.obolibrary.org/obo/GO_1901462 GO:1901463 biolink:BiologicalProcess regulation of tetrapyrrole biosynthetic process Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process. go-plus.json regulation of tetrapyrrole synthesis|regulation of tetrapyrrole formation|regulation of tetrapyrrole biosynthesis|regulation of tetrapyrrole anabolism http://purl.obolibrary.org/obo/GO_1901463 GO:1901471 biolink:BiologicalProcess positive regulation of syringal lignin catabolic process Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process. go-plus.json positive regulation of syringal lignin catabolism|upregulation of syringal lignin degradation|up-regulation of syringal lignin catabolic process|activation of S-lignin catabolic process|up regulation of syringal lignin catabolism|upregulation of syringal lignin breakdown|positive regulation of S-lignin catabolic process|up regulation of S-lignin catabolic process|upregulation of syringal lignin catabolic process|up regulation of syringal lignin degradation|upregulation of syringal lignin catabolism|positive regulation of syringal lignin degradation|up regulation of syringal lignin breakdown|positive regulation of syringal lignin breakdown|activation of syringal lignin degradation|upregulation of S-lignin catabolic process|up regulation of syringal lignin catabolic process|up-regulation of syringal lignin catabolism|activation of syringal lignin catabolic process|activation of syringal lignin breakdown|up-regulation of syringal lignin degradation|activation of syringal lignin catabolism|up-regulation of S-lignin catabolic process|up-regulation of syringal lignin breakdown http://purl.obolibrary.org/obo/GO_1901471 GO:1901472 biolink:BiologicalProcess regulation of Golgi calcium ion export Any process that modulates the frequency, rate or extent of Golgi calcium ion export. go-plus.json http://purl.obolibrary.org/obo/GO_1901472 GO:1901470 biolink:BiologicalProcess negative regulation of syringal lignin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process. go-plus.json inhibition of syringal lignin catabolic process|inhibition of syringal lignin breakdown|negative regulation of S-lignin catabolic process|down-regulation of S-lignin catabolic process|down regulation of syringal lignin degradation|downregulation of syringal lignin catabolism|downregulation of syringal lignin degradation|down regulation of syringal lignin catabolism|down regulation of syringal lignin breakdown|downregulation of S-lignin catabolic process|down regulation of syringal lignin catabolic process|downregulation of syringal lignin breakdown|down regulation of S-lignin catabolic process|inhibition of syringal lignin catabolism|downregulation of syringal lignin catabolic process|down-regulation of syringal lignin degradation|negative regulation of syringal lignin degradation|negative regulation of syringal lignin breakdown|down-regulation of syringal lignin breakdown|inhibition of S-lignin catabolic process|down-regulation of syringal lignin catabolic process|negative regulation of syringal lignin catabolism|down-regulation of syringal lignin catabolism|inhibition of syringal lignin degradation http://purl.obolibrary.org/obo/GO_1901470 GO:1901479 biolink:MolecularActivity benomyl transmembrane transporter activity Enables the transfer of benomyl from one side of a membrane to the other. go-plus.json benomyl transporter activity http://purl.obolibrary.org/obo/GO_1901479 GO:1901477 biolink:BiologicalProcess benomyl transmembrane transport The directed movement of benomyl across a membrane. go-plus.json benomyl membrane transport http://purl.obolibrary.org/obo/GO_1901477 GO:1901478 biolink:MolecularActivity aminotriazole transmembrane transporter activity Enables the transfer of amitrole from one side of a membrane to the other. go-plus.json aminotriazole transporter activity http://purl.obolibrary.org/obo/GO_1901478 GO:1901475 biolink:BiologicalProcess pyruvate transmembrane transport The directed movement of pyruvate across a membrane. go-plus.json pyruvate membrane transport http://purl.obolibrary.org/obo/GO_1901475 GO:1901476 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901476 GO:1901473 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901473 GO:1901474 biolink:MolecularActivity azole transmembrane transporter activity Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other. go-plus.json azole transporter activity http://purl.obolibrary.org/obo/GO_1901474 GO:0035595 biolink:MolecularActivity N-acetylglucosaminylinositol deacetylase activity Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol. EC:3.5.1.103|KEGG_REACTION:R09651|RHEA:26180|MetaCyc:RXN1G-2 go-plus.json 1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase activity|1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase activity|GlcNAc-Ins deacetylase activity|N-acetyl-1D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity http://purl.obolibrary.org/obo/GO_0035595 GO:1901482 biolink:BiologicalProcess L-lysine import into vacuole involved in cellular response to nitrogen starvation A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1901482 GO:1901483 biolink:BiologicalProcess regulation of transcription factor catabolic process Any process that modulates the frequency, rate or extent of transcription factor catabolic process. go-plus.json regulation of transcription factor breakdown|regulation of proteasome-mediated transcription factor catabolism|regulation of transcription factor catabolism|regulation of transcription factor degradation|regulation of sequence-specific DNA binding transcription factor catabolic process http://purl.obolibrary.org/obo/GO_1901483 GO:0035596 biolink:MolecularActivity methylthiotransferase activity Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor. go-plus.json MTTase http://purl.obolibrary.org/obo/GO_0035596 GO:0035597 biolink:MolecularActivity N6-isopentenyladenosine methylthiotransferase activity Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A). go-plus.json i6A methylthiotransferase activity http://purl.obolibrary.org/obo/GO_0035597 GO:1901480 biolink:MolecularActivity oleate transmembrane transporter activity Enables the transfer of oleate from one side of a membrane to the other. RHEA:33655 go-plus.json oleate transporter activity http://purl.obolibrary.org/obo/GO_1901480 GO:0035598 biolink:MolecularActivity N6-threonylcarbomyladenosine methylthiotransferase activity Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A). Reactome:R-HSA-6786571 go-plus.json t6A methylthiotransferase activity http://purl.obolibrary.org/obo/GO_0035598 GO:1901481 biolink:BiologicalProcess L-glutamate import involved in cellular response to nitrogen starvation Any L-glutamate import that is involved in cellular response to nitrogen starvation. go-plus.json L-glutamate uptake involved in cellular response to nitrogen starvation http://purl.obolibrary.org/obo/GO_1901481 GO:0035599 biolink:MolecularActivity aspartic acid methylthiotransferase activity Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid. RESID:AA0232 go-plus.json http://purl.obolibrary.org/obo/GO_0035599 GO:0035590 biolink:BiologicalProcess purinergic nucleotide receptor signaling pathway The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity. go-plus.json purinergic receptor signalling pathway|purinoceptor signaling pathway|purinergic receptor signaling pathway|P2 receptor signaling pathway|purinergic nucleotide receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035590 GO:0035591 biolink:MolecularActivity signaling adaptor activity The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity. go-plus.json signaling scaffold activity|signalling adaptor activity http://purl.obolibrary.org/obo/GO_0035591 GO:0035592 biolink:BiologicalProcess establishment of protein localization to extracellular region The directed movement of a protein to a specific location within the extracellular region. go-plus.json establishment of protein localisation in extracellular region|establishment of protein localization in extracellular region http://purl.obolibrary.org/obo/GO_0035592 GO:0035593 biolink:BiologicalProcess positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region. go-plus.json positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localisation in extracellular region|positive regulation of Wnt signaling range|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt diffusion|positive regulation of Wnt-activated signaling pathway by establishment of Wnt protein localization to extracellular region|positive regulation of Wnt receptor signalling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0035593 GO:0035594 biolink:MolecularActivity ganglioside binding Binding to a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues. go-plus.json http://purl.obolibrary.org/obo/GO_0035594 GO:1901488 biolink:BiologicalProcess obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process OBSOLETE. Negative regulation of transcription factor catabolism that results in positive regulation of the SREBP signaling pathway. go-plus.json positive regulation of SREBP signaling pathway by inhibition of SREBP degradation|positive regulation of SREBP-mediated signaling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP-mediated signalling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation|positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolism http://purl.obolibrary.org/obo/GO_1901488 GO:1901489 biolink:BiologicalProcess obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels OBSOLETE. Negative regulation of transcription factor catabolism in response to decreased oxygen levels, which results in positive regulation of the SREBP signaling pathway. go-plus.json positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation, in response to decreased oxygen|positive regulation of SREBP-mediated signaling pathway in absence of oxygen by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling by negative regulation of transcription factor catabolism at low oxygen levels|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling by inhibition of SREBP degradation in response to decreased oxygen levels http://purl.obolibrary.org/obo/GO_1901489 GO:1901486 biolink:BiologicalProcess obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process OBSOLETE. Positive regulation of transcription factor catabolism that results in negative regulation of the SREBP signaling pathway. go-plus.json negative regulation of SREBP-mediated signalling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation|negative regulation of SREBP-mediated signaling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolism http://purl.obolibrary.org/obo/GO_1901486 GO:1901487 biolink:BiologicalProcess obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels OBSOLETE. Positive regulation of transcription factor catabolism in response to increased oxygen levels, which results in negative regulation of the SREBP signaling pathway. go-plus.json negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation, in response to elevated oxygen|negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling by acceleration of SREBP degradation, in response to increased oxygen levels|negative regulation of SREBP signaling by positive regulation of transcription factor catabolism in response to increased oxygen levels|negative regulation of SREBP-mediated signaling pathway in presence of oxygen by positive regulation of transcription factor catabolic process http://purl.obolibrary.org/obo/GO_1901487 GO:1901484 biolink:BiologicalProcess negative regulation of transcription factor catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of transcription factor catabolic process. go-plus.json down regulation of sequence-specific DNA binding transcription factor catabolic process|down regulation of transcription factor breakdown|downregulation of transcription factor catabolic process|inhibition of transcription factor degradation|inhibition of proteasome-mediated transcription factor catabolism|down regulation of transcription factor catabolic process|inhibition of sequence-specific DNA binding transcription factor catabolic process|inhibition of transcription factor catabolic process|inhibition of transcription factor breakdown|inhibition of transcription factor catabolism|down regulation of proteasome-mediated transcription factor catabolism|downregulation of proteasome-mediated transcription factor catabolism|down-regulation of transcription factor degradation|down regulation of transcription factor catabolism|negative regulation of transcription factor degradation|negative regulation of sequence-specific DNA binding transcription factor catabolic process|down-regulation of sequence-specific DNA binding transcription factor catabolic process|downregulation of transcription factor catabolism|negative regulation of transcription factor breakdown|down-regulation of transcription factor breakdown|negative regulation of proteasome-mediated transcription factor catabolism|down-regulation of proteasome-mediated transcription factor catabolism|downregulation of transcription factor degradation|down-regulation of transcription factor catabolic process|downregulation of sequence-specific DNA binding transcription factor catabolic process|negative regulation of transcription factor catabolism|down-regulation of transcription factor catabolism|down regulation of transcription factor degradation|downregulation of transcription factor breakdown http://purl.obolibrary.org/obo/GO_1901484 GO:1901485 biolink:BiologicalProcess positive regulation of transcription factor catabolic process Any process that activates or increases the frequency, rate or extent of transcription factor catabolic process. go-plus.json activation of transcription factor catabolism|up regulation of transcription factor catabolic process|up-regulation of proteasome-mediated transcription factor catabolism|upregulation of transcription factor degradation|upregulation of sequence-specific DNA binding transcription factor catabolic process|up-regulation of transcription factor catabolism|upregulation of transcription factor breakdown|upregulation of proteasome-mediated transcription factor catabolism|up-regulation of transcription factor degradation|upregulation of transcription factor catabolic process|up-regulation of sequence-specific DNA binding transcription factor catabolic process|upregulation of transcription factor catabolism|up-regulation of transcription factor breakdown|activation of transcription factor degradation|up regulation of proteasome-mediated transcription factor catabolism|up-regulation of transcription factor catabolic process|activation of sequence-specific DNA binding transcription factor catabolic process|activation of transcription factor catabolic process|positive regulation of proteasome-mediated transcription factor catabolism|activation of transcription factor breakdown|positive regulation of transcription factor degradation|up regulation of transcription factor degradation|positive regulation of sequence-specific DNA binding transcription factor catabolic process|up regulation of transcription factor catabolism|positive regulation of transcription factor catabolism|up regulation of sequence-specific DNA binding transcription factor catabolic process|positive regulation of transcription factor breakdown|activation of proteasome-mediated transcription factor catabolism|up regulation of transcription factor breakdown http://purl.obolibrary.org/obo/GO_1901485 GO:1901493 biolink:BiologicalProcess response to decalin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901493 GO:0035584 biolink:BiologicalProcess calcium-mediated signaling using intracellular calcium source A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response. go-plus.json calcium signaling using intracellular calcium source|calcium-mediated signalling using intracellular calcium source|calcium signalling using intracellular calcium source http://purl.obolibrary.org/obo/GO_0035584 GO:0035585 biolink:BiologicalProcess calcium-mediated signaling using extracellular calcium source A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response. go-plus.json calcium-mediated signalling using extracellular calcium source|extracellular calcium influx|calcium signalling using extracellular calcium source|calcium signaling using extracellular calcium source http://purl.obolibrary.org/obo/GO_0035585 GO:1901494 biolink:BiologicalProcess regulation of cysteine metabolic process Any process that modulates the frequency, rate or extent of cysteine metabolic process. go-plus.json regulation of cysteine metabolism http://purl.obolibrary.org/obo/GO_1901494 GO:1901491 biolink:BiologicalProcess negative regulation of lymphangiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. go-plus.json inhibition of lymph vessel formation|inhibition of lymphangiogenesis|down regulation of lymphangiogenesis|negative regulation of lymph vessel formation|down-regulation of lymph vessel formation|downregulation of lymphangiogenesis|downregulation of lymph vessel formation|down-regulation of lymphangiogenesis|down regulation of lymph vessel formation http://purl.obolibrary.org/obo/GO_1901491 GO:0035586 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035586 GO:0035587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035587 GO:1901492 biolink:BiologicalProcess positive regulation of lymphangiogenesis Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. go-plus.json upregulation of lymph vessel formation|up-regulation of lymphangiogenesis|up-regulation of lymph vessel formation|activation of lymph vessel formation|upregulation of lymphangiogenesis|positive regulation of lymph vessel formation|up regulation of lymphangiogenesis|activation of lymphangiogenesis|up regulation of lymph vessel formation http://purl.obolibrary.org/obo/GO_1901492 GO:0035588 biolink:BiologicalProcess G protein-coupled purinergic receptor signaling pathway The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. go-plus.json G-protein coupled purinergic receptor signaling pathway|G-protein coupled purinergic receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035588 GO:1901490 biolink:BiologicalProcess regulation of lymphangiogenesis Any process that modulates the frequency, rate or extent of lymphangiogenesis. go-plus.json regulation of lymph vessel formation http://purl.obolibrary.org/obo/GO_1901490 GO:0035589 biolink:BiologicalProcess G protein-coupled purinergic nucleotide receptor signaling pathway The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. go-plus.json G-protein coupled purinergic nucleotide receptor signalling pathway|G-protein coupled purinergic nucleotide receptor signaling pathway|P2Y receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035589 GO:0035580 biolink:CellularComponent specific granule lumen The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. go-plus.json secondary granule lumen http://purl.obolibrary.org/obo/GO_0035580 GO:0035581 biolink:BiologicalProcess sequestering of extracellular ligand from receptor The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor. go-plus.json negative regulation of protein bioavailability|extracellular sequestering of receptor ligand http://purl.obolibrary.org/obo/GO_0035581 GO:0035582 biolink:BiologicalProcess sequestering of BMP in extracellular matrix Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins. go-plus.json negative regulation of bone morphogenetic protein signaling pathway by extracellular matrix sequestering of bone morphogenetic protein|BMP sequestration in the ECM|negative regulation of BMP signaling pathway by extracellular sequestering of BMP|negative regulation of BMP signalling pathway by extracellular matrix sequestering of BMP http://purl.obolibrary.org/obo/GO_0035582 GO:0035583 biolink:BiologicalProcess sequestering of TGFbeta in extracellular matrix Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins. go-plus.json negative regulation of transforming growth factor beta receptor signalling pathway by extracellular matrix sequestering of TGFbeta|negative regulation of transforming growth factor beta receptor signaling pathway by extracellular matrix sequestering of TGFbeta|sequestering of TGFbeta large latency complex in extracellular matrix|sequestering of TGFbeta LLC in extracellular matrix http://purl.obolibrary.org/obo/GO_0035583 GO:1901499 biolink:BiologicalProcess response to hexane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901499 GO:1901497 biolink:BiologicalProcess response to diphenyl ether Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901497 GO:1901498 biolink:BiologicalProcess response to tetralin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901498 GO:1901495 biolink:BiologicalProcess negative regulation of cysteine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process. go-plus.json negative regulation of cysteine metabolism|down-regulation of cysteine metabolism|down-regulation of cysteine metabolic process|inhibition of cysteine metabolism|downregulation of cysteine metabolic process|down regulation of cysteine metabolic process|down regulation of cysteine metabolism|inhibition of cysteine metabolic process|downregulation of cysteine metabolism http://purl.obolibrary.org/obo/GO_1901495 GO:1901496 biolink:BiologicalProcess positive regulation of cysteine metabolic process Any process that activates or increases the frequency, rate or extent of cysteine metabolic process. go-plus.json up regulation of cysteine metabolism|positive regulation of cysteine metabolism|activation of cysteine metabolism|up-regulation of cysteine metabolic process|activation of cysteine metabolic process|up-regulation of cysteine metabolism|up regulation of cysteine metabolic process|upregulation of cysteine metabolism|upregulation of cysteine metabolic process http://purl.obolibrary.org/obo/GO_1901496 GO:0035573 biolink:BiologicalProcess N-terminal peptidyl-serine trimethylation The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine. go-plus.json http://purl.obolibrary.org/obo/GO_0035573 GO:0035574 biolink:BiologicalProcess histone H4-K20 demethylation The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0035574 GO:0035575 biolink:MolecularActivity histone H4-methyl-lysine-20 demethylase activity Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. Reactome:R-HSA-2172678 go-plus.json histone H4K20me demethylase activity|histone demethylase activity (H4-K20 specific) http://purl.obolibrary.org/obo/GO_0035575 GO:0035576 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in pronephric field specification The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop. go-plus.json retinoic acid receptor signalling pathway involved in pronephric field specification http://purl.obolibrary.org/obo/GO_0035576 GO:0035577 biolink:CellularComponent azurophil granule membrane The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. go-plus.json primary granule membrane http://purl.obolibrary.org/obo/GO_0035577 GO:0035578 biolink:CellularComponent azurophil granule lumen The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. go-plus.json primary granule lumen http://purl.obolibrary.org/obo/GO_0035578 GO:0035579 biolink:CellularComponent specific granule membrane The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. go-plus.json secondary granule membrane http://purl.obolibrary.org/obo/GO_0035579 GO:0035570 biolink:BiologicalProcess N-terminal peptidyl-serine methylation The methylation of the N-terminal serine of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0035570 GO:0035571 biolink:BiologicalProcess N-terminal peptidyl-serine monomethylation The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine. go-plus.json http://purl.obolibrary.org/obo/GO_0035571 GO:0035572 biolink:BiologicalProcess N-terminal peptidyl-serine dimethylation The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine. go-plus.json http://purl.obolibrary.org/obo/GO_0035572 GO:0035562 biolink:BiologicalProcess negative regulation of chromatin binding Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0035562 GO:0035563 biolink:BiologicalProcess positive regulation of chromatin binding Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0035563 GO:0035564 biolink:BiologicalProcess regulation of kidney size Any process that modulates the size of a kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0035564 GO:0035565 biolink:BiologicalProcess regulation of pronephros size Any process that modulates the size of a pronephric kidney. go-plus.json regulation of pronephric kidney size http://purl.obolibrary.org/obo/GO_0035565 GO:0035566 biolink:BiologicalProcess regulation of metanephros size Any process that modulates the size of a metanephric kidney. go-plus.json regulation of metanephric kidney size http://purl.obolibrary.org/obo/GO_0035566 GO:0035567 biolink:BiologicalProcess non-canonical Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin. go-plus.json beta-catenin-independent Wnt receptor signaling pathway|non-canonical Wnt receptor signalling pathway|non-canonical Wnt receptor signaling pathway|non-canonical Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_0035567 GO:0035568 biolink:BiologicalProcess N-terminal peptidyl-proline methylation The methylation of the N-terminal proline of proteins. RESID:AA0419 go-plus.json http://purl.obolibrary.org/obo/GO_0035568 GO:0035569 biolink:BiologicalProcess obsolete N-terminal peptidyl-proline trimethylation OBSOLETE. The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline. go-plus.json N-terminal peptidyl-proline trimethylation http://purl.obolibrary.org/obo/GO_0035569 GO:0035560 biolink:MolecularActivity pheophorbidase activity Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a. EC:3.1.1.82|RHEA:32483 go-plus.json phedase activity|pheophoridase activity|PPD activity http://purl.obolibrary.org/obo/GO_0035560 GO:0035561 biolink:BiologicalProcess regulation of chromatin binding Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0035561 GO:0035559 biolink:BiologicalProcess obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. go-plus.json MAPKKK cascade involved in signaling from the EGFR|MAPKKK cascade involved in epidermal growth factor receptor signalling|MAPKKK cascade involved in epidermal growth factor receptor signaling http://purl.obolibrary.org/obo/GO_0035559 GO:0035551 biolink:BiologicalProcess protein initiator methionine removal involved in protein maturation Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0035551 GO:0035552 biolink:BiologicalProcess oxidative single-stranded DNA demethylation Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. go-plus.json oxidative ssDNA demethylation http://purl.obolibrary.org/obo/GO_0035552 GO:0035553 biolink:BiologicalProcess oxidative single-stranded RNA demethylation Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. go-plus.json oxidative ssRNA demethylation http://purl.obolibrary.org/obo/GO_0035553 GO:0035554 biolink:BiologicalProcess termination of Roundabout signal transduction The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated. go-plus.json http://purl.obolibrary.org/obo/GO_0035554 GO:0035555 biolink:BiologicalProcess obsolete initiation of Roundabout signal transduction OBSOLETE. The process in which a SLIT protein causes activation of the receptor, Roundabout (ROBO). go-plus.json initiation of Roundabout signal transduction http://purl.obolibrary.org/obo/GO_0035555 GO:0035556 biolink:BiologicalProcess intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. go-plus.json signal transduction via intracellular signaling cascade|protein kinase cascade|intracellular signaling chain|intracellular signal transduction pathway|signal transmission via intracellular cascade|intracellular signaling cascade|intracellular protein kinase cascade|intracellular signaling pathway http://purl.obolibrary.org/obo/GO_0035556 goslim_drosophila GO:0035557 biolink:BiologicalProcess obsolete intracellular signal transduction involved in cell surface receptor linked signaling OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. go-plus.json intracellular signaling chain involved in cell surface receptor signaling|intracellular signaling cascade involved in cell surface receptor linked signaling|intracellular signal transduction involved in cell surface receptor linked signalling|intracellular signal transduction involved in cell surface receptor linked signaling http://purl.obolibrary.org/obo/GO_0035557 GO:0035558 biolink:BiologicalProcess obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. go-plus.json phosphoinositide 3-kinase cascade involved in insulin receptor signaling|phosphatidylinositol 3-kinase cascade involved in insulin receptor signalling|PI3K cascade involved in signaling from the insulin receptor|phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling|phosphoinositide 3-kinase cascade involved in insulin receptor signalling http://purl.obolibrary.org/obo/GO_0035558 GO:0035550 biolink:CellularComponent urease complex A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide). go-plus.json http://purl.obolibrary.org/obo/GO_0035550 CHEBI:36628 biolink:ChemicalSubstance 1,8-naphthyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36628 chebi_ph7_3 UBERON:0013498 biolink:AnatomicalEntity vestibulo-cochlear VIII ganglion complex go-plus.json vestibular VIII ganglion complex|vestibulocochlear VIII ganglion complex|vestibulocochlear ganglion complex http://purl.obolibrary.org/obo/UBERON_0013498 CHEBI:36622 biolink:ChemicalSubstance benzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36622 GO:0060510 biolink:BiologicalProcess type II pneumocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. go-plus.json granular pneumocyte differentiation|large alveolar cell differentiation|great alveolar cell differentiation http://purl.obolibrary.org/obo/GO_0060510 GO:0060511 biolink:BiologicalProcess creation of an inductive signal by a mesenchymal cell involved in lung induction The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060511 GO:0060512 biolink:BiologicalProcess prostate gland morphogenesis The process in which the anatomical structures of a prostate gland are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060512 GO:0060513 biolink:BiologicalProcess prostatic bud formation The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. go-plus.json prostate gland formation|primary prostate bud formation|prostate ductal budding http://purl.obolibrary.org/obo/GO_0060513 CHEBI:36623 biolink:ChemicalSubstance 4H-benzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36623 chebi_ph7_3 GO:0060514 biolink:BiologicalProcess prostate induction The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060514 CHEBI:36624 biolink:ChemicalSubstance naphthyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36624 GO:0060515 biolink:BiologicalProcess prostate field specification The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop. go-plus.json http://purl.obolibrary.org/obo/GO_0060515 GO:0060516 biolink:BiologicalProcess primary prostatic bud elongation The increase in size of the prostatic bud as it forms. go-plus.json prostate bud elongation involved in prostate morphogenesis|prostate bud elongation http://purl.obolibrary.org/obo/GO_0060516 GO:0060517 biolink:BiologicalProcess epithelial cell proliferation involved in prostatic bud elongation The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060517 GO:0060518 biolink:BiologicalProcess cell migration involved in prostatic bud elongation The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060518 GO:0060519 biolink:BiologicalProcess cell adhesion involved in prostatic bud elongation The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060519 CHEBI:36638 biolink:ChemicalSubstance fucosyl glycosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36638 CHEBI:36639 biolink:ChemicalSubstance 2H-benzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36639 chebi_ph7_3 GO:0060500 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0060500 GO:0060501 biolink:BiologicalProcess positive regulation of epithelial cell proliferation involved in lung morphogenesis Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. go-plus.json http://purl.obolibrary.org/obo/GO_0060501 GO:0060502 biolink:BiologicalProcess epithelial cell proliferation involved in lung morphogenesis The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. go-plus.json http://purl.obolibrary.org/obo/GO_0060502 GO:0060503 biolink:BiologicalProcess bud dilation involved in lung branching The process in which a bud in the lung increases radially. go-plus.json bud expansion http://purl.obolibrary.org/obo/GO_0060503 CHEBI:36635 biolink:ChemicalSubstance p-toluic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36635 GO:0060504 biolink:BiologicalProcess positive regulation of epithelial cell proliferation involved in lung bud dilation Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially. go-plus.json http://purl.obolibrary.org/obo/GO_0060504 GO:0060505 biolink:BiologicalProcess epithelial cell proliferation involved in lung bud dilation The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060505 GO:0060506 biolink:BiologicalProcess smoothened signaling pathway involved in lung development The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development. go-plus.json hedgehog signaling pathway involved in lung development|hh signaling pathway involved in lung development|smoothened signalling pathway involved in lung development http://purl.obolibrary.org/obo/GO_0060506 GO:0060507 biolink:BiologicalProcess epidermal growth factor receptor signaling pathway involved in lung development The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development. go-plus.json epidermal growth factor receptor signalling pathway involved in lung development http://purl.obolibrary.org/obo/GO_0060507 GO:0060508 biolink:BiologicalProcess lung basal cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell. go-plus.json pulmonary basal cell differentiation http://purl.obolibrary.org/obo/GO_0060508 GO:0060509 biolink:BiologicalProcess type I pneumocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. go-plus.json squamous alveolar cell differentiation|membranous pneumocyte differentiation|small alveolar cell differentiation http://purl.obolibrary.org/obo/GO_0060509 CHEBI:36607 biolink:ChemicalSubstance cyclic acid anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36607 CHEBI:36608 biolink:ChemicalSubstance acyclic acid anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36608 UBERON:0013478 biolink:AnatomicalEntity cecal tonsil A thickened round patch of lymphoid tissue located at the ileocecal junction adjacent to the sacculus rotundus. go-plus.json caecal tonsil|cecal GALT http://purl.obolibrary.org/obo/UBERON_0013478 UBERON:0013479 biolink:AnatomicalEntity lung endothelium A blood vessel endothelium that is part of a lung [Automatically generated definition]. go-plus.json respiratory endothelium http://purl.obolibrary.org/obo/UBERON_0013479 CHEBI:36606 biolink:ChemicalSubstance acid anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36606 CHEBI:36609 biolink:ChemicalSubstance cyclic dicarboxylic anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36609 GO:0060530 biolink:BiologicalProcess smooth muscle cell differentiation involved in prostate glandular acinus development The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus. go-plus.json http://purl.obolibrary.org/obo/GO_0060530 GO:0060531 biolink:BiologicalProcess neuroendocrine cell differentiation involved in prostate gland acinus development The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus. go-plus.json http://purl.obolibrary.org/obo/GO_0060531 GO:0060532 biolink:BiologicalProcess bronchus cartilage development The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go-plus.json pulmonary cartilage development http://purl.obolibrary.org/obo/GO_0060532 GO:0060533 biolink:BiologicalProcess bronchus cartilage morphogenesis The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. go-plus.json http://purl.obolibrary.org/obo/GO_0060533 GO:0060534 biolink:BiologicalProcess trachea cartilage development The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0060534 GO:0060535 biolink:BiologicalProcess trachea cartilage morphogenesis The process in which the anatomical structures of cartilage in the trachea are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060535 CHEBI:36602 biolink:ChemicalSubstance 2-dehydro-L-idonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36602 chebi_ph7_3 GO:0060536 biolink:BiologicalProcess cartilage morphogenesis The process in which the anatomical structures of cartilage are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060536 GO:0060537 biolink:BiologicalProcess muscle tissue development The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0060537 GO:0060538 biolink:BiologicalProcess skeletal muscle organ development The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060538 GO:0060539 biolink:BiologicalProcess diaphragm development The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. go-plus.json http://purl.obolibrary.org/obo/GO_0060539 CHEBI:36611 biolink:ChemicalSubstance fenchane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36611 chebi_ph7_3 GO:0060520 biolink:BiologicalProcess activation of prostate induction by androgen receptor signaling pathway Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland. go-plus.json activation of prostate induction by androgen receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060520 GO:0060521 biolink:BiologicalProcess mesenchymal-epithelial cell signaling involved in prostate induction Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate. go-plus.json mesenchymal-epithelial cell signalling involved in prostate induction http://purl.obolibrary.org/obo/GO_0060521 GO:0060522 biolink:BiologicalProcess inductive mesenchymal to epithelial cell signaling Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells. go-plus.json inductive mesenchymal to epithelial cell signalling http://purl.obolibrary.org/obo/GO_0060522 GO:0060523 biolink:BiologicalProcess prostate epithelial cord elongation The developmental growth process in which solid chords of prostate epithelium increase in length. go-plus.json http://purl.obolibrary.org/obo/GO_0060523 CHEBI:36615 biolink:ChemicalSubstance triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36615 GO:0060524 biolink:BiologicalProcess dichotomous subdivision of prostate epithelial cord terminal unit The process in which a prostate epithelial cord bifurcates at its end. go-plus.json prostate epithelial cord bifurcation http://purl.obolibrary.org/obo/GO_0060524 CHEBI:36612 biolink:ChemicalSubstance (1R,4S)-fenchone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36612 chebi_ph7_3 GO:0060525 biolink:BiologicalProcess prostate glandular acinus development The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060525 GO:0060526 biolink:BiologicalProcess prostate glandular acinus morphogenesis The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060526 GO:0060527 biolink:BiologicalProcess prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini. go-plus.json http://purl.obolibrary.org/obo/GO_0060527 GO:0060528 biolink:BiologicalProcess secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate. go-plus.json http://purl.obolibrary.org/obo/GO_0060528 GO:0060529 biolink:BiologicalProcess squamous basal epithelial stem cell differentiation involved in prostate gland acinus development The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate. go-plus.json http://purl.obolibrary.org/obo/GO_0060529 GO:1901408 biolink:BiologicalProcess negative regulation of phosphorylation of RNA polymerase II C-terminal domain Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. go-plus.json down regulation of generation of II(0) form of RNA polymerase II|downregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|downregulation of phosphorylation of RNA polymerase II C-terminal domain|downregulation of generation of II(0) form of RNA polymerase II|down-regulation of CTD domain phosphorylation of RNA polymerase II|negative regulation of CTD domain phosphorylation of RNA polymerase II|negative regulation of generation of hyperphosphorylated CTD of RNA polymerase II|down-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|down regulation of phosphorylation of RNA polymerase II C-terminal domain|inhibition of phosphorylation of RNA polymerase II C-terminal domain|negative regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|down-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|negative regulation of generation of II(0) form of RNA polymerase II|down-regulation of generation of II(0) form of RNA polymerase II|downregulation of generation of hyperphosphorylated CTD of RNA polymerase II|inhibition of CTD domain phosphorylation of RNA polymerase II|down regulation of generation of hyperphosphorylated CTD of RNA polymerase II|inhibition of hyperphosphorylation of RNA polymerase II C-terminal domain|down regulation of CTD domain phosphorylation of RNA polymerase II|inhibition of generation of II(0) form of RNA polymerase II|down-regulation of phosphorylation of RNA polymerase II C-terminal domain|inhibition of generation of hyperphosphorylated CTD of RNA polymerase II|downregulation of CTD domain phosphorylation of RNA polymerase II|down regulation of hyperphosphorylation of RNA polymerase II C-terminal domain http://purl.obolibrary.org/obo/GO_1901408 GO:1901409 biolink:BiologicalProcess positive regulation of phosphorylation of RNA polymerase II C-terminal domain Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. go-plus.json up regulation of CTD domain phosphorylation of RNA polymerase II|up-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|up regulation of phosphorylation of RNA polymerase II C-terminal domain|positive regulation of CTD domain phosphorylation of RNA polymerase II|up regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of generation of hyperphosphorylated CTD of RNA polymerase II|positive regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of CTD domain phosphorylation of RNA polymerase II|up regulation of generation of II(0) form of RNA polymerase II|positive regulation of generation of II(0) form of RNA polymerase II|upregulation of phosphorylation of RNA polymerase II C-terminal domain|positive regulation of generation of hyperphosphorylated CTD of RNA polymerase II|activation of hyperphosphorylation of RNA polymerase II C-terminal domain|up-regulation of CTD domain phosphorylation of RNA polymerase II|up regulation of generation of hyperphosphorylated CTD of RNA polymerase II|activation of generation of II(0) form of RNA polymerase II|up-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|up-regulation of phosphorylation of RNA polymerase II C-terminal domain|up-regulation of generation of II(0) form of RNA polymerase II|activation of phosphorylation of RNA polymerase II C-terminal domain|upregulation of CTD domain phosphorylation of RNA polymerase II|upregulation of generation of hyperphosphorylated CTD of RNA polymerase II|upregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|upregulation of generation of II(0) form of RNA polymerase II http://purl.obolibrary.org/obo/GO_1901409 GO:1901406 biolink:BiologicalProcess positive regulation of tetrapyrrole catabolic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process. go-plus.json activation of tetrapyrrole catabolism|up regulation of tetrapyrrole catabolic process|upregulation of tetrapyrrole degradation|up-regulation of tetrapyrrole catabolism|upregulation of tetrapyrrole breakdown|upregulation of tetrapyrrole catabolic process|up-regulation of tetrapyrrole degradation|upregulation of tetrapyrrole catabolism|up-regulation of tetrapyrrole breakdown|activation of tetrapyrrole degradation|up-regulation of tetrapyrrole catabolic process|activation of tetrapyrrole catabolic process|positive regulation of tetrapyrrole degradation|activation of tetrapyrrole breakdown|up regulation of tetrapyrrole degradation|up regulation of tetrapyrrole catabolism|positive regulation of tetrapyrrole catabolism|positive regulation of tetrapyrrole breakdown|up regulation of tetrapyrrole breakdown http://purl.obolibrary.org/obo/GO_1901406 GO:1901407 biolink:BiologicalProcess regulation of phosphorylation of RNA polymerase II C-terminal domain Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. go-plus.json regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|regulation of generation of II(0) form of RNA polymerase II|regulation of generation of hyperphosphorylated CTD of RNA polymerase II|regulation of CTD domain phosphorylation of RNA polymerase II http://purl.obolibrary.org/obo/GO_1901407 GO:1901404 biolink:BiologicalProcess regulation of tetrapyrrole catabolic process Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process. go-plus.json regulation of tetrapyrrole breakdown|regulation of tetrapyrrole catabolism|regulation of tetrapyrrole degradation http://purl.obolibrary.org/obo/GO_1901404 GO:1901405 biolink:BiologicalProcess negative regulation of tetrapyrrole catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process. go-plus.json down regulation of tetrapyrrole breakdown|downregulation of tetrapyrrole catabolic process|inhibition of tetrapyrrole degradation|down regulation of tetrapyrrole catabolic process|inhibition of tetrapyrrole catabolic process|inhibition of tetrapyrrole breakdown|inhibition of tetrapyrrole catabolism|negative regulation of tetrapyrrole degradation|down regulation of tetrapyrrole catabolism|down-regulation of tetrapyrrole degradation|downregulation of tetrapyrrole catabolism|negative regulation of tetrapyrrole breakdown|down-regulation of tetrapyrrole breakdown|down-regulation of tetrapyrrole catabolic process|downregulation of tetrapyrrole degradation|down regulation of tetrapyrrole degradation|down-regulation of tetrapyrrole catabolism|negative regulation of tetrapyrrole catabolism|downregulation of tetrapyrrole breakdown http://purl.obolibrary.org/obo/GO_1901405 GO:1901402 biolink:BiologicalProcess negative regulation of tetrapyrrole metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process. go-plus.json down regulation of tetrapyrrole metabolic process|inhibition of tetrapyrrole metabolic process|down-regulation of tetrapyrrole metabolism|negative regulation of tetrapyrrole metabolism|inhibition of tetrapyrrole metabolism|down-regulation of tetrapyrrole metabolic process|down regulation of tetrapyrrole metabolism|downregulation of tetrapyrrole metabolism|downregulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_1901402 GO:1901403 biolink:BiologicalProcess positive regulation of tetrapyrrole metabolic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process. go-plus.json upregulation of tetrapyrrole metabolic process|activation of tetrapyrrole metabolism|up-regulation of tetrapyrrole metabolism|up-regulation of tetrapyrrole metabolic process|activation of tetrapyrrole metabolic process|upregulation of tetrapyrrole metabolism|up regulation of tetrapyrrole metabolic process|up regulation of tetrapyrrole metabolism|positive regulation of tetrapyrrole metabolism http://purl.obolibrary.org/obo/GO_1901403 GO:1901400 biolink:BiologicalProcess positive regulation of transforming growth factor beta3 activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation. go-plus.json upregulation of TGFB3 activation|positive regulation of TGF-beta 3 activation|activation of TGFbeta 3 activation|up regulation of transforming growth factor beta3 activation|activation of transforming growth factor beta3 activation|activation of TGF-beta 3 activation|positive regulation of TGFbeta 3 activation|up regulation of TGFbeta 3 activation|up-regulation of TGFB3 activation|up-regulation of TGF-beta 3 activation|activation of TGFB3 activation|up-regulation of transforming growth factor beta3 activation|upregulation of TGFbeta 3 activation|positive regulation of TGFB3 activation|upregulation of TGF-beta 3 activation|up regulation of TGFB3 activation|upregulation of transforming growth factor beta3 activation|up-regulation of TGFbeta 3 activation|up regulation of TGF-beta 3 activation http://purl.obolibrary.org/obo/GO_1901400 GO:1901401 biolink:BiologicalProcess regulation of tetrapyrrole metabolic process Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process. go-plus.json regulation of tetrapyrrole metabolism http://purl.obolibrary.org/obo/GO_1901401 GO:0060550 biolink:BiologicalProcess positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0060550 GO:0060551 biolink:BiologicalProcess regulation of fructose 1,6-bisphosphate metabolic process Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0060551 GO:0060552 biolink:BiologicalProcess positive regulation of fructose 1,6-bisphosphate metabolic process Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0060552 GO:0060553 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060553 GO:0060554 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060554 GO:0060555 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060555 GO:0060556 biolink:BiologicalProcess regulation of vitamin D biosynthetic process Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json http://purl.obolibrary.org/obo/GO_0060556 GO:0060557 biolink:BiologicalProcess positive regulation of vitamin D biosynthetic process Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json http://purl.obolibrary.org/obo/GO_0060557 GO:0060558 biolink:BiologicalProcess regulation of calcidiol 1-monooxygenase activity Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0060558 GO:0060559 biolink:BiologicalProcess positive regulation of calcidiol 1-monooxygenase activity Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0060559 GO:1901419 biolink:BiologicalProcess regulation of response to alcohol Any process that modulates the frequency, rate or extent of response to alcohol. go-plus.json http://purl.obolibrary.org/obo/GO_1901419 GO:1901417 biolink:BiologicalProcess negative regulation of response to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol. go-plus.json down regulation of response to ethanol|downregulation of response to ethanol|down-regulation of response to ethanol|inhibition of response to ethanol http://purl.obolibrary.org/obo/GO_1901417 GO:1901418 biolink:BiologicalProcess positive regulation of response to ethanol Any process that activates or increases the frequency, rate or extent of response to ethanol. go-plus.json upregulation of response to ethanol|up regulation of response to ethanol|activation of response to ethanol|up-regulation of response to ethanol http://purl.obolibrary.org/obo/GO_1901418 GO:1901415 biolink:BiologicalProcess positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA. go-plus.json activation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|activation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|positive regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|up regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole formation from glycine and succinyl-CoA|upregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|upregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole formation from glycine and succinyl-CoA|up-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|positive regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|activation of tetrapyrrole anabolism from glycine and succinyl-CoA|up-regulation of tetrapyrrole formation from glycine and succinyl-CoA http://purl.obolibrary.org/obo/GO_1901415 GO:1901416 biolink:BiologicalProcess regulation of response to ethanol Any process that modulates the frequency, rate or extent of response to ethanol. go-plus.json http://purl.obolibrary.org/obo/GO_1901416 GO:1901413 biolink:BiologicalProcess regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA. go-plus.json regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|regulation of tetrapyrrole formation from glycine and succinyl-CoA|regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA http://purl.obolibrary.org/obo/GO_1901413 GO:1901414 biolink:BiologicalProcess negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA. go-plus.json down-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|down-regulation of tetrapyrrole formation from glycine and succinyl-CoA|negative regulation of tetrapyrrole formation from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|downregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|downregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole formation from glycine and succinyl-CoA|down regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|down regulation of tetrapyrrole formation from glycine and succinyl-CoA|inhibition of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole synthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|inhibition of tetrapyrrole formation from glycine and succinyl-CoA|down-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|negative regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA http://purl.obolibrary.org/obo/GO_1901414 GO:1901411 biolink:BiologicalProcess negative regulation of tetrapyrrole biosynthetic process from glutamate Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate. go-plus.json negative regulation of tetrapyrrole synthesis from glutamate|down-regulation of tetrapyrrole synthesis from glutamate|negative regulation of tetrapyrrole biosynthesis from glutamate|down-regulation of tetrapyrrole biosynthetic process from glutamate|down-regulation of tetrapyrrole biosynthesis from glutamate|negative regulation of tetrapyrrole anabolism from glutamate|down-regulation of tetrapyrrole anabolism from glutamate|inhibition of tetrapyrrole formation from glutamate|downregulation of tetrapyrrole biosynthetic process from glutamate|downregulation of tetrapyrrole biosynthesis from glutamate|inhibition of tetrapyrrole synthesis from glutamate|down regulation of tetrapyrrole biosynthesis from glutamate|down regulation of tetrapyrrole biosynthetic process from glutamate|inhibition of tetrapyrrole anabolism from glutamate|down regulation of tetrapyrrole formation from glutamate|inhibition of tetrapyrrole biosynthetic process from glutamate|down regulation of tetrapyrrole synthesis from glutamate|downregulation of tetrapyrrole formation from glutamate|inhibition of tetrapyrrole biosynthesis from glutamate|down regulation of tetrapyrrole anabolism from glutamate|downregulation of tetrapyrrole synthesis from glutamate|downregulation of tetrapyrrole anabolism from glutamate|negative regulation of tetrapyrrole formation from glutamate|down-regulation of tetrapyrrole formation from glutamate http://purl.obolibrary.org/obo/GO_1901411 GO:1901412 biolink:BiologicalProcess positive regulation of tetrapyrrole biosynthetic process from glutamate Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate. go-plus.json up regulation of tetrapyrrole anabolism from glutamate|activation of tetrapyrrole formation from glutamate|positive regulation of tetrapyrrole anabolism from glutamate|activation of tetrapyrrole biosynthesis from glutamate|activation of tetrapyrrole synthesis from glutamate|up-regulation of tetrapyrrole formation from glutamate|activation of tetrapyrrole anabolism from glutamate|positive regulation of tetrapyrrole biosynthesis from glutamate|up-regulation of tetrapyrrole synthesis from glutamate|up regulation of tetrapyrrole biosynthetic process from glutamate|up regulation of tetrapyrrole biosynthesis from glutamate|up-regulation of tetrapyrrole anabolism from glutamate|upregulation of tetrapyrrole formation from glutamate|upregulation of tetrapyrrole synthesis from glutamate|upregulation of tetrapyrrole biosynthesis from glutamate|upregulation of tetrapyrrole biosynthetic process from glutamate|upregulation of tetrapyrrole anabolism from glutamate|up regulation of tetrapyrrole formation from glutamate|positive regulation of tetrapyrrole formation from glutamate|up regulation of tetrapyrrole synthesis from glutamate|activation of tetrapyrrole biosynthetic process from glutamate|up-regulation of tetrapyrrole biosynthetic process from glutamate|up-regulation of tetrapyrrole biosynthesis from glutamate|positive regulation of tetrapyrrole synthesis from glutamate http://purl.obolibrary.org/obo/GO_1901412 GO:1901410 biolink:BiologicalProcess regulation of tetrapyrrole biosynthetic process from glutamate Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate. go-plus.json regulation of tetrapyrrole biosynthesis from glutamate|regulation of tetrapyrrole formation from glutamate|regulation of tetrapyrrole synthesis from glutamate|regulation of tetrapyrrole anabolism from glutamate http://purl.obolibrary.org/obo/GO_1901410 GO:0060540 biolink:BiologicalProcess diaphragm morphogenesis The process in which the anatomical structures of the diaphragm are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060540 GO:0060541 biolink:BiologicalProcess respiratory system development The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0060541 goslim_drosophila GO:0060542 biolink:BiologicalProcess regulation of strand invasion Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060542 GO:0060543 biolink:BiologicalProcess negative regulation of strand invasion Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. go-plus.json negative regulation of D-loop biosynthesis|negative regulation of D-loop formation|negative regulation of Rad51-mediated strand invasion http://purl.obolibrary.org/obo/GO_0060543 GO:0060544 biolink:BiologicalProcess regulation of necroptotic process Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. go-plus.json regulation of necroptosis http://purl.obolibrary.org/obo/GO_0060544 GO:0060545 biolink:BiologicalProcess positive regulation of necroptotic process Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. go-plus.json positive regulation of necroptosis http://purl.obolibrary.org/obo/GO_0060545 GO:0060546 biolink:BiologicalProcess negative regulation of necroptotic process Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. go-plus.json negative regulation of necroptosis http://purl.obolibrary.org/obo/GO_0060546 GO:0060547 biolink:BiologicalProcess negative regulation of necrotic cell death Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. go-plus.json http://purl.obolibrary.org/obo/GO_0060547 GO:0060548 biolink:BiologicalProcess negative regulation of cell death Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0060548 GO:0060549 biolink:BiologicalProcess regulation of fructose 1,6-bisphosphate 1-phosphatase activity Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0060549 GO:1901428 biolink:BiologicalProcess regulation of syringal lignin biosynthetic process Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process. go-plus.json regulation of syringal lignin biosynthesis|regulation of S-lignin biosynthetic process|regulation of syringal lignin anabolism|regulation of syringal lignin synthesis|regulation of syringal lignin formation http://purl.obolibrary.org/obo/GO_1901428 GO:1901429 biolink:BiologicalProcess negative regulation of syringal lignin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process. go-plus.json inhibition of S-lignin biosynthetic process|down-regulation of syringal lignin synthesis|negative regulation of syringal lignin synthesis|down-regulation of syringal lignin formation|negative regulation of syringal lignin formation|downregulation of syringal lignin biosynthetic process|downregulation of syringal lignin biosynthesis|down regulation of S-lignin biosynthetic process|inhibition of syringal lignin anabolism|down regulation of syringal lignin biosynthesis|down regulation of syringal lignin biosynthetic process|downregulation of S-lignin biosynthetic process|inhibition of syringal lignin biosynthetic process|inhibition of syringal lignin synthesis|down regulation of syringal lignin anabolism|inhibition of syringal lignin formation|inhibition of syringal lignin biosynthesis|downregulation of syringal lignin anabolism|down regulation of syringal lignin synthesis|down-regulation of S-lignin biosynthetic process|negative regulation of S-lignin biosynthetic process|down regulation of syringal lignin formation|downregulation of syringal lignin synthesis|downregulation of syringal lignin formation|down-regulation of syringal lignin anabolism|negative regulation of syringal lignin biosynthesis|negative regulation of syringal lignin anabolism|down-regulation of syringal lignin biosynthesis|down-regulation of syringal lignin biosynthetic process http://purl.obolibrary.org/obo/GO_1901429 GO:1901426 biolink:BiologicalProcess response to furfural Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901426 GO:1901427 biolink:BiologicalProcess response to propan-1-ol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901427 GO:1901424 biolink:BiologicalProcess response to toluene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901424 GO:1901425 biolink:BiologicalProcess response to formic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901425 GO:1901422 biolink:BiologicalProcess response to butan-1-ol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus. go-plus.json process resulting in tolerance to butan-1-ol http://purl.obolibrary.org/obo/GO_1901422 GO:1901423 biolink:BiologicalProcess response to benzene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901423 GO:1901420 biolink:BiologicalProcess negative regulation of response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol. go-plus.json down regulation of response to alcohol|downregulation of response to alcohol|down-regulation of response to alcohol|inhibition of response to alcohol http://purl.obolibrary.org/obo/GO_1901420 GO:1901421 biolink:BiologicalProcess positive regulation of response to alcohol Any process that activates or increases the frequency, rate or extent of response to alcohol. go-plus.json upregulation of response to alcohol|up regulation of response to alcohol|activation of response to alcohol|up-regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901421 GO:0060570 biolink:BiologicalProcess negative regulation of peptide hormone processing Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. go-plus.json http://purl.obolibrary.org/obo/GO_0060570 GO:0060571 biolink:BiologicalProcess morphogenesis of an epithelial fold The morphogenetic process in which an epithelial sheet bends along a linear axis. go-plus.json folding of an epithelial sheet|epithelial folding http://purl.obolibrary.org/obo/GO_0060571 UBERON:0037447 biolink:AnatomicalEntity wall of male urethra go-plus.json male urethral wall http://purl.obolibrary.org/obo/UBERON_0037447 GO:0060572 biolink:BiologicalProcess morphogenesis of an epithelial bud The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. go-plus.json http://purl.obolibrary.org/obo/GO_0060572 GO:0060573 biolink:BiologicalProcess cell fate specification involved in pattern specification The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060573 GO:0060574 biolink:BiologicalProcess intestinal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus. go-plus.json http://purl.obolibrary.org/obo/GO_0060574 GO:0060575 biolink:BiologicalProcess intestinal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0060575 GO:0060576 biolink:BiologicalProcess intestinal epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060576 GO:0060577 biolink:BiologicalProcess pulmonary vein morphogenesis The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. go-plus.json pulmonary venous blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0060577 GO:0060578 biolink:BiologicalProcess superior vena cava morphogenesis The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060578 GO:0060579 biolink:BiologicalProcess ventral spinal cord interneuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. go-plus.json http://purl.obolibrary.org/obo/GO_0060579 NCBITaxon:2301094 biolink:OrganismalEntity Diplogasteroidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2301094 GO:1901439 biolink:BiologicalProcess positive regulation of toluene metabolic process Any process that activates or increases the frequency, rate or extent of toluene metabolic process. go-plus.json upregulation of toluene metabolic process|up-regulation of methylbenzene metabolic process|positive regulation of toluene metabolism|upregulation of methylbenzene metabolism|up regulation of toluene metabolism|upregulation of methylbenzene metabolic process|up regulation of toluene metabolic process|activation of toluene metabolic process|up-regulation of methylbenzene metabolism|upregulation of toluene metabolism|activation of methylbenzene metabolism|up regulation of methylbenzene metabolic process|positive regulation of methylbenzene metabolic process|up-regulation of toluene metabolic process|up-regulation of toluene metabolism|positive regulation of methylbenzene metabolism|up regulation of methylbenzene metabolism|activation of methylbenzene metabolic process|activation of toluene metabolism http://purl.obolibrary.org/obo/GO_1901439 GO:1901437 biolink:BiologicalProcess regulation of toluene metabolic process Any process that modulates the frequency, rate or extent of toluene metabolic process. go-plus.json regulation of toluene metabolism|regulation of methylbenzene metabolic process|regulation of methylbenzene metabolism http://purl.obolibrary.org/obo/GO_1901437 GO:1901438 biolink:BiologicalProcess negative regulation of toluene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process. go-plus.json down regulation of methylbenzene metabolism|down regulation of toluene metabolic process|inhibition of methylbenzene metabolic process|downregulation of toluene metabolic process|downregulation of toluene metabolism|inhibition of methylbenzene metabolism|down regulation of toluene metabolism|down regulation of methylbenzene metabolic process|down-regulation of toluene metabolic process|downregulation of methylbenzene metabolic process|inhibition of toluene metabolism|negative regulation of methylbenzene metabolism|down-regulation of methylbenzene metabolism|inhibition of toluene metabolic process|down-regulation of methylbenzene metabolic process|negative regulation of methylbenzene metabolic process|downregulation of methylbenzene metabolism|negative regulation of toluene metabolism|down-regulation of toluene metabolism http://purl.obolibrary.org/obo/GO_1901438 GO:1901435 biolink:BiologicalProcess negative regulation of toluene catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process. go-plus.json downregulation of toluene catabolism|downregulation of toluene degradation|down regulation of toluene catabolism|down regulation of toluene breakdown|down regulation of toluene catabolic process|downregulation of toluene breakdown|inhibition of toluene catabolism|negative regulation of toluene degradation|downregulation of toluene catabolic process|down-regulation of toluene degradation|down-regulation of toluene breakdown|negative regulation of toluene breakdown|down-regulation of toluene catabolic process|negative regulation of toluene catabolism|down-regulation of toluene catabolism|inhibition of toluene degradation|inhibition of toluene catabolic process|inhibition of toluene breakdown|down regulation of toluene degradation http://purl.obolibrary.org/obo/GO_1901435 UBERON:0037455 biolink:AnatomicalEntity wall of female urethra go-plus.json female urethral wall http://purl.obolibrary.org/obo/UBERON_0037455 GO:1901436 biolink:BiologicalProcess positive regulation of toluene catabolic process Any process that activates or increases the frequency, rate or extent of toluene catabolic process. go-plus.json upregulation of toluene breakdown|upregulation of toluene catabolic process|up regulation of toluene degradation|upregulation of toluene catabolism|positive regulation of toluene degradation|up regulation of toluene breakdown|activation of toluene degradation|positive regulation of toluene breakdown|up regulation of toluene catabolic process|up-regulation of toluene catabolism|activation of toluene catabolic process|activation of toluene breakdown|up-regulation of toluene degradation|activation of toluene catabolism|up-regulation of toluene breakdown|positive regulation of toluene catabolism|up-regulation of toluene catabolic process|upregulation of toluene degradation|up regulation of toluene catabolism http://purl.obolibrary.org/obo/GO_1901436 GO:1901433 biolink:BiologicalProcess positive regulation of response to cycloalkane Any process that activates or increases the frequency, rate or extent of response to cycloalkane. go-plus.json up regulation of response to cycloalkane|activation of response to cycloalkane|up-regulation of response to cycloalkane|upregulation of response to cycloalkane http://purl.obolibrary.org/obo/GO_1901433 GO:1901434 biolink:BiologicalProcess regulation of toluene catabolic process Any process that modulates the frequency, rate or extent of toluene catabolic process. go-plus.json regulation of toluene degradation|regulation of toluene catabolism|regulation of toluene breakdown http://purl.obolibrary.org/obo/GO_1901434 GO:1901431 biolink:BiologicalProcess regulation of response to cycloalkane Any process that modulates the frequency, rate or extent of response to cycloalkane. go-plus.json http://purl.obolibrary.org/obo/GO_1901431 UBERON:0037459 biolink:AnatomicalEntity hair of limb go-plus.json limb hair http://purl.obolibrary.org/obo/UBERON_0037459 GO:1901432 biolink:BiologicalProcess negative regulation of response to cycloalkane Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane. go-plus.json down-regulation of response to cycloalkane|inhibition of response to cycloalkane|down regulation of response to cycloalkane|downregulation of response to cycloalkane http://purl.obolibrary.org/obo/GO_1901432 GO:0060560 biolink:BiologicalProcess developmental growth involved in morphogenesis The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. go-plus.json differential growth http://purl.obolibrary.org/obo/GO_0060560 GO:1901430 biolink:BiologicalProcess positive regulation of syringal lignin biosynthetic process Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process. go-plus.json activation of S-lignin biosynthetic process|up-regulation of syringal lignin biosynthesis|up-regulation of syringal lignin biosynthetic process|activation of syringal lignin biosynthetic process|up regulation of syringal lignin anabolism|positive regulation of syringal lignin anabolism|up-regulation of S-lignin biosynthetic process|up regulation of syringal lignin synthesis|activation of syringal lignin biosynthesis|positive regulation of syringal lignin synthesis|activation of syringal lignin anabolism|up regulation of syringal lignin formation|positive regulation of syringal lignin formation|positive regulation of syringal lignin biosynthesis|activation of syringal lignin synthesis|up regulation of syringal lignin biosynthesis|up regulation of syringal lignin biosynthetic process|upregulation of S-lignin biosynthetic process|up-regulation of syringal lignin anabolism|activation of syringal lignin formation|up-regulation of syringal lignin synthesis|up-regulation of syringal lignin formation|upregulation of syringal lignin biosynthesis|upregulation of syringal lignin biosynthetic process|upregulation of syringal lignin anabolism|up regulation of S-lignin biosynthetic process|positive regulation of S-lignin biosynthetic process|upregulation of syringal lignin synthesis|upregulation of syringal lignin formation http://purl.obolibrary.org/obo/GO_1901430 UBERON:0037458 biolink:AnatomicalEntity hair of neck go-plus.json neck hair http://purl.obolibrary.org/obo/UBERON_0037458 GO:0060561 biolink:BiologicalProcess apoptotic process involved in morphogenesis Any apoptotic process that contributes to the shaping of an anatomical structure. go-plus.json apoptosis involved in development|apoptosis involved in morphogenesis|morphogenetic apoptosis http://purl.obolibrary.org/obo/GO_0060561 GO:0060562 biolink:BiologicalProcess epithelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. go-plus.json http://purl.obolibrary.org/obo/GO_0060562 GO:0060563 biolink:BiologicalProcess neuroepithelial cell differentiation The process in which epiblast cells acquire specialized features of neuroepithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060563 GO:0060564 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060564 GO:0060565 biolink:BiologicalProcess obsolete inhibition of APC-Cdc20 complex activity OBSOLETE. Any process that prevents the activation of APC-Cdc20 complex activity regulating the mitotic cell cycle. go-plus.json inhibition of cyclosome activity during mitotic cell cycle|inhibition of APC/C activity during mitotic cell cycle|inhibition of mitotic anaphase-promoting complex activity|inhibition of APC-Cdc20 complex activity|inhibition of APC activity during mitotic cell cycle http://purl.obolibrary.org/obo/GO_0060565 GO:0060566 biolink:BiologicalProcess positive regulation of DNA-templated transcription, termination Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. go-plus.json positive regulation of termination of DNA-dependent transcription|positive regulation of DNA-dependent transcription, termination|positive regulation of transcription termination, DNA-dependent http://purl.obolibrary.org/obo/GO_0060566 GO:0060567 biolink:BiologicalProcess negative regulation of DNA-templated transcription, termination Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. go-plus.json negative regulation of termination of DNA-dependent transcription|negative regulation of DNA-dependent transcription, termination|negative regulation of transcription termination, DNA-dependent http://purl.obolibrary.org/obo/GO_0060567 GO:0060568 biolink:BiologicalProcess regulation of peptide hormone processing Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. go-plus.json http://purl.obolibrary.org/obo/GO_0060568 GO:0060569 biolink:BiologicalProcess positive regulation of peptide hormone processing Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. go-plus.json http://purl.obolibrary.org/obo/GO_0060569 UBERON:0003728 biolink:AnatomicalEntity mediastinum The central part of the thoracic cavity enclosed by the left and right pleurae. go-plus.json mediastinal part of chest http://purl.obolibrary.org/obo/UBERON_0003728 UBERON:0003729 biolink:AnatomicalEntity mouth mucosa A mucous membrane that lines the mouth. go-plus.json tunica mucosa oris|buccal mucosa|mucous membrane of mouth|mucosa of mouth|mouth mucosa|oral part of viscerocranial mucosa|mucosal lining of mouth|oral mucosa|oral mucous membrane|mouth organ mucosa|mouth mucous membrane|tunica mucosa oris http://purl.obolibrary.org/obo/UBERON_0003729 UBERON:0003726 biolink:AnatomicalEntity thoracic nerve The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls. go-plus.json nervi thoracici|pectoral nerve|nervus thoracis|thoracic spinal nerve http://purl.obolibrary.org/obo/UBERON_0003726 UBERON:0003727 biolink:AnatomicalEntity intercostal nerve The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]. go-plus.json anterior ramus of thoracic nerve|ventral ramus of thoracic spinal nerve|nervi intercostales|ramus anterior, nervus thoracicus|anterior ramus of thoracic spinal nerve|thoracic anterior ramus http://purl.obolibrary.org/obo/UBERON_0003727 UBERON:0003725 biolink:AnatomicalEntity cervical nerve plexus An arrangement of nerve fibers, running from the spine that travels to the head and neck where it innervates skin and muscle. go-plus.json cervical nerve plexus|plexus cervicalis|plexus cervicalis|cervical plexus http://purl.obolibrary.org/obo/UBERON_0003725 GO:0035702 biolink:BiologicalProcess monocyte homeostasis The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0035702 GO:0035703 biolink:BiologicalProcess monocyte migration into blood stream The movement of a monocyte from the bone marrow to the blood stream. go-plus.json release of monocytes into circulation http://purl.obolibrary.org/obo/GO_0035703 GO:0035704 biolink:BiologicalProcess helper T cell chemotaxis The directed movement of a helper T cell in response to an external stimulus. go-plus.json T-helper cell chemotaxis http://purl.obolibrary.org/obo/GO_0035704 GO:0035705 biolink:BiologicalProcess T-helper 17 cell chemotaxis The directed movement of a T-helper 17 cell in response to an external stimulus. go-plus.json Th17 cell chemotaxis http://purl.obolibrary.org/obo/GO_0035705 GO:0035706 biolink:BiologicalProcess T-helper 1 cell chemotaxis The directed movement of a T-helper 1 cell in response to an external stimulus. go-plus.json Th1 cell chemotaxis http://purl.obolibrary.org/obo/GO_0035706 GO:0035707 biolink:BiologicalProcess T-helper 2 cell chemotaxis The directed movement of a T-helper 2 cell in response to an external stimulus. go-plus.json Th2 cell chemotaxis http://purl.obolibrary.org/obo/GO_0035707 GO:0035708 biolink:BiologicalProcess interleukin-4-dependent isotype switching to IgE isotypes The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4). go-plus.json IL-4-dependent isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0035708 GO:0035709 biolink:BiologicalProcess memory T cell activation The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json http://purl.obolibrary.org/obo/GO_0035709 CHEBI:85521 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85521 CHEBI:61555 biolink:ChemicalSubstance dUTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61555 chebi_ph7_3 CHEBI:61556 biolink:ChemicalSubstance (KDO)2-(palmitoleoyl-myristoyl)-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_61556 CHEBI:61553 biolink:ChemicalSubstance D-fructofuranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61553 CHEBI:36586 biolink:ChemicalSubstance carbonyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36586 CHEBI:85524 biolink:ChemicalSubstance (3E,5Z,8Z,11Z,14Z)-icosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85524 CHEBI:36587 biolink:ChemicalSubstance organic oxo compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36587 CHEBI:61559 biolink:ChemicalSubstance D-psicose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61559 CHEBI:61557 biolink:ChemicalSubstance nucleoside triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61557 chebi_ph7_3 CHEBI:85528 biolink:ChemicalSubstance 3-(methylthio)acryloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85528 GO:0035700 biolink:BiologicalProcess astrocyte chemotaxis The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_0035700 CHEBI:61558 biolink:ChemicalSubstance (KDO)2-(palmitoleoyl)-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61558 GO:0035701 biolink:BiologicalProcess hematopoietic stem cell migration The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. go-plus.json hemopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0035701 CHEBI:85529 biolink:ChemicalSubstance 3-hydroxy-3-(methylthio)propanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85529 NCBITaxon:9030 biolink:OrganismalEntity Gallus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9030 NCBITaxon:9031 biolink:OrganismalEntity Gallus gallus go-plus.json chickens|Gallus gallus domesticus|chicken|bantam|Gallus domesticus http://purl.obolibrary.org/obo/NCBITaxon_9031 UBERON:0003715 biolink:AnatomicalEntity splanchnic nerve The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia. go-plus.json visceral nerve|splanchnic nerves http://purl.obolibrary.org/obo/UBERON_0003715 UBERON:0003716 biolink:AnatomicalEntity recurrent laryngeal nerve A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch. go-plus.json nervus laryngeus recurrens|recurrent nerve|vagus X nerve recurrent laryngeal branch|recurrent laryngeal nerve from vagus nerve|inferior laryngeal nerve|ramus recurrens http://purl.obolibrary.org/obo/UBERON_0003716 UBERON:0003713 biolink:AnatomicalEntity splenic vein A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein. go-plus.json vena splenica|lienal vein|vena lienalis http://purl.obolibrary.org/obo/UBERON_0003713 UBERON:0003714 biolink:AnatomicalEntity neural tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. go-plus.json nerve tissue|portion of neural tissue|nervous tissue http://purl.obolibrary.org/obo/UBERON_0003714 CHEBI:131602 biolink:ChemicalSubstance CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131602 CHEBI:131603 biolink:ChemicalSubstance sucrose 6(G)-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131603 CHEBI:131604 biolink:ChemicalSubstance Mycoplasma genitalium metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_131604 CHEBI:131605 biolink:ChemicalSubstance dicarboxylic acid monoester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131605 CHEBI:61562 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61562 chebi_ph7_3 CHEBI:61563 biolink:ChemicalSubstance farnesyl triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61563 chebi_ph7_3 CHEBI:61560 biolink:ChemicalSubstance 2'-deoxyribonucleoside 5'-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61560 chebi_ph7_3 CHEBI:85510 biolink:ChemicalSubstance 7-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85510 CHEBI:61561 biolink:ChemicalSubstance beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61561 CHEBI:61566 biolink:ChemicalSubstance L-alanyl-D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61566 CHEBI:85511 biolink:ChemicalSubstance 6-(acylmethyl)-4-hydroxy-2H-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85511 CHEBI:61567 biolink:ChemicalSubstance D-hexopyranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61567 chebi_ph7_3 CHEBI:61564 biolink:ChemicalSubstance L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61564 CHEBI:85514 biolink:ChemicalSubstance 6-alkyl-4-hydroxy-2H-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85514 chebi_ph7_3 CHEBI:61565 biolink:ChemicalSubstance L-alanyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61565 CHEBI:85517 biolink:ChemicalSubstance acarbose 7(IV)-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85517 UBERON:0003723 biolink:AnatomicalEntity vestibular nerve The vestibular nerve is one of the two branches of the Vestibulocochlear nerve (the cochlear nerve being the other). It goes to the semicircular canals via the vestibular ganglion. It receives positional information. Axons of the vestibular nerve synapse in the vestibular nucleus on the lateral floor and wall of the fourth ventricle in the pons and medulla. It arises from bipolar cells in the vestibular ganglion, ganglion of Scarpa, which is situated in the upper part of the outer end of the internal auditory meatus. [WP,unvetted]. go-plus.json nervus vestibularis|vestibulocochlear VIII nerve vestibular component|scarpa ganglion|vestibular root of eighth cranial nerve|scarpa's ganglion|scarpas ganglion|vestibular root of acoustic nerve|vestibulocochlear nerve vestibular root http://purl.obolibrary.org/obo/UBERON_0003723 UBERON:0003721 biolink:AnatomicalEntity lingual nerve The lingual nerve is a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue. It also carries fibers from the facial nerve, which return taste information from the anterior two thirds of the tongue. go-plus.json trigeminal nerve lingual branch|trigeminal V nerve lingual branch|lingual branch of trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0003721 UBERON:0003709 biolink:AnatomicalEntity circle of Willis A circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle go-plus.json arterial circle|cerebral arterial circle|arterial circle of Willis|Willis circle|circulus arteriosus cerebri http://purl.obolibrary.org/obo/UBERON_0003709 UBERON:0003704 biolink:AnatomicalEntity intrahepatic bile duct Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. go-plus.json bile duct intrahepatic part|intrahepatic biliary system http://purl.obolibrary.org/obo/UBERON_0003704 UBERON:0003703 biolink:AnatomicalEntity extrahepatic bile duct Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. go-plus.json bile duct extrahepatic part|extrahepatic biliary system http://purl.obolibrary.org/obo/UBERON_0003703 CHEBI:85541 biolink:ChemicalSubstance elemental bismuth go-plus.json http://purl.obolibrary.org/obo/CHEBI_85541 CHEBI:61574 biolink:ChemicalSubstance D-glycero-alpha-D-manno-heptose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61574 chebi_ph7_3 CHEBI:85543 biolink:ChemicalSubstance bismuth ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85543 CHEBI:61572 biolink:ChemicalSubstance digalactosylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61572 CHEBI:36564 biolink:ChemicalSubstance N-benzoyl-4-methoxyanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36564 chebi_ph7_3 CHEBI:61575 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61575 CHEBI:85547 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85547 chebi_ph7_3 CHEBI:85548 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85548 chebi_ph7_3 CHEBI:85549 biolink:ChemicalSubstance 9alpha-hydroxyandrost-4-en-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_85549 chebi_ph7_3 UBERON:0003711 biolink:AnatomicalEntity brachiocephalic vein The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava. go-plus.json innominate vein|brachiocephalic venous tree|innominate vein|innominate veins|innomiate vein|venae anonyma|vena brachiocephalica|innominate trunk http://purl.obolibrary.org/obo/UBERON_0003711 CHEBI:36562 biolink:ChemicalSubstance main-group coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_36562 CHEBI:85530 biolink:ChemicalSubstance N(1),N(8)-bis(coumaroyl)spermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85530 CHEBI:85531 biolink:ChemicalSubstance trans-4-coumaroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85531 CHEBI:85532 biolink:ChemicalSubstance D-galactaro-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_85532 CHEBI:85533 biolink:ChemicalSubstance trans-4-hydroxy-L-proline betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85533 chebi_ph7_3 CHEBI:85534 biolink:ChemicalSubstance cis-4-hydroxy-D-proline betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85534 chebi_ph7_3 CHEBI:61589 biolink:ChemicalSubstance 4-phospho-(KDO)-lipid IVA(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61589 chebi_ph7_3 CHEBI:61586 biolink:ChemicalSubstance S-(hydroxymethyl)mycothiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61586 chebi_ph7_3 CHEBI:36575 biolink:ChemicalSubstance N-formylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36575 CHEBI:85538 biolink:ChemicalSubstance (R)-(2-chloro-5-oxo-2,5-dihydro-2-furyl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85538 chebi_ph7_3 CHEBI:36571 biolink:ChemicalSubstance prenylglycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36571 GO:1901806 biolink:BiologicalProcess beta-glucoside biosynthetic process The chemical reactions and pathways resulting in the formation of beta-glucoside. go-plus.json beta-glucoside biosynthesis|beta-glucoside anabolism|beta-glucoside synthesis|beta-glucoside formation http://purl.obolibrary.org/obo/GO_1901806 GO:1901807 biolink:BiologicalProcess capsanthin metabolic process The chemical reactions and pathways involving capsanthin. go-plus.json capsanthin metabolism http://purl.obolibrary.org/obo/GO_1901807 GO:1901804 biolink:BiologicalProcess beta-glucoside metabolic process The chemical reactions and pathways involving beta-glucoside. go-plus.json beta-glucoside metabolism http://purl.obolibrary.org/obo/GO_1901804 GO:1901805 biolink:BiologicalProcess beta-glucoside catabolic process The chemical reactions and pathways resulting in the breakdown of beta-glucoside. go-plus.json beta-glucoside degradation|beta-glucoside catabolism|beta-glucoside breakdown http://purl.obolibrary.org/obo/GO_1901805 GO:1901802 biolink:BiologicalProcess 1,5-anhydro-D-fructose catabolic process The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose. go-plus.json 1,5-anhydro-D-fructose degradation|1,5-anhydro-D-fructose breakdown|1,5-anhydro-D-fructose catabolism http://purl.obolibrary.org/obo/GO_1901802 GO:1901803 biolink:BiologicalProcess 1,5-anhydro-D-fructose biosynthetic process The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose. go-plus.json 1,5-anhydro-D-fructose anabolism|1,5-anhydro-D-fructose synthesis|1,5-anhydro-D-fructose biosynthesis|1,5-anhydro-D-fructose formation http://purl.obolibrary.org/obo/GO_1901803 GO:1901800 biolink:BiologicalProcess positive regulation of proteasomal protein catabolic process Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process. go-plus.json up regulation of proteasome-mediated protein catabolic process|up-regulation of proteasome-mediated protein catabolism|upregulation of proteasomal protein catabolic process|positive regulation of proteasome-mediated protein catabolic process|activation of proteasome-mediated protein catabolism|activation of proteasome-mediated protein catabolic process|up regulation of proteasomal protein catabolic process|positive regulation of proteasome-mediated protein catabolism|up-regulation of proteasome-mediated protein catabolic process|up regulation of proteasome-mediated protein catabolism|activation of proteasomal protein catabolic process|upregulation of proteasome-mediated protein catabolic process|upregulation of proteasome-mediated protein catabolism|up-regulation of proteasomal protein catabolic process http://purl.obolibrary.org/obo/GO_1901800 GO:1901801 biolink:BiologicalProcess 1,5-anhydro-D-fructose metabolic process The chemical reactions and pathways involving 1,5-anhydro-D-fructose. go-plus.json 1,5-anhydro-D-fructose metabolism http://purl.obolibrary.org/obo/GO_1901801 CHEBI:85560 biolink:ChemicalSubstance (5Z)-icosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85560 CHEBI:61596 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-D-Gal go-plus.json http://purl.obolibrary.org/obo/CHEBI_61596 CHEBI:85563 biolink:ChemicalSubstance lysophosphatidylcholine 6:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85563 chebi_ph7_3 CHEBI:85564 biolink:ChemicalSubstance phosphatidylcholine 24:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85564 chebi_ph7_3 CHEBI:61593 biolink:ChemicalSubstance D-glycero-beta-D-manno-heptose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61593 chebi_ph7_3 CHEBI:61599 biolink:ChemicalSubstance [8)-alpha-Neu5Ac-(2->]n go-plus.json http://purl.obolibrary.org/obo/CHEBI_61599 CHEBI:36544 biolink:ChemicalSubstance sialodiosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36544 CHEBI:36542 biolink:ChemicalSubstance sialopentaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36542 CHEBI:36543 biolink:ChemicalSubstance sialotetraosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36543 GO:0060710 biolink:BiologicalProcess chorio-allantoic fusion The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois. go-plus.json http://purl.obolibrary.org/obo/GO_0060710 GO:0060711 biolink:BiologicalProcess labyrinthine layer development The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060711 CHEBI:36546 biolink:ChemicalSubstance sialomonoglycosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36546 GO:0060712 biolink:BiologicalProcess spongiotrophoblast layer development The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060712 CHEBI:36547 biolink:ChemicalSubstance pimarane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36547 chebi_ph7_3 GO:0060713 biolink:BiologicalProcess labyrinthine layer morphogenesis The process in which the labyrinthine layer of the placenta is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060713 GO:0060714 biolink:BiologicalProcess labyrinthine layer formation The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0060714 GO:0060715 biolink:BiologicalProcess syncytiotrophoblast cell differentiation involved in labyrinthine layer development The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0060715 GO:0060716 biolink:BiologicalProcess labyrinthine layer blood vessel development The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. go-plus.json http://purl.obolibrary.org/obo/GO_0060716 NCBITaxon:9072 biolink:OrganismalEntity Phasianinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9072 GO:0060717 biolink:BiologicalProcess chorion development The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0060717 CHEBI:36540 biolink:ChemicalSubstance ent-kaurane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36540 chebi_ph7_3 GO:0060718 biolink:BiologicalProcess chorionic trophoblast cell differentiation The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. go-plus.json http://purl.obolibrary.org/obo/GO_0060718 CHEBI:36541 biolink:ChemicalSubstance sialotriaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36541 GO:0060719 biolink:BiologicalProcess chorionic trophoblast cell development The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060719 GO:1901808 biolink:BiologicalProcess capsanthin catabolic process The chemical reactions and pathways resulting in the breakdown of capsanthin. go-plus.json capsanthin degradation|capsanthin breakdown|capsanthin catabolism http://purl.obolibrary.org/obo/GO_1901808 GO:1901809 biolink:BiologicalProcess capsanthin biosynthetic process The chemical reactions and pathways resulting in the formation of capsanthin. go-plus.json capsanthin biosynthesis|capsanthin anabolism|capsanthin synthesis|capsanthin formation http://purl.obolibrary.org/obo/GO_1901809 GO:1901817 biolink:BiologicalProcess beta-zeacarotene catabolic process The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene. go-plus.json beta-zeacarotene degradation|beta-zeacarotene breakdown|beta-zeacarotene catabolism http://purl.obolibrary.org/obo/GO_1901817 NCBITaxon:1351751 biolink:OrganismalEntity Parastagonospora go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1351751 GO:1901818 biolink:BiologicalProcess beta-zeacarotene biosynthetic process The chemical reactions and pathways resulting in the formation of beta-zeacarotene. go-plus.json beta-zeacarotene anabolism|beta-zeacarotene synthesis|beta-zeacarotene biosynthesis|beta-zeacarotene formation http://purl.obolibrary.org/obo/GO_1901818 GO:1901815 biolink:BiologicalProcess astaxanthin biosynthetic process The chemical reactions and pathways resulting in the formation of astaxanthin. go-plus.json astaxanthin anabolism|astaxanthin synthesis|astaxanthin formation|astaxanthin biosynthesis http://purl.obolibrary.org/obo/GO_1901815 GO:1901816 biolink:BiologicalProcess beta-zeacarotene metabolic process The chemical reactions and pathways involving beta-zeacarotene. go-plus.json beta-zeacarotene metabolism http://purl.obolibrary.org/obo/GO_1901816 GO:1901813 biolink:BiologicalProcess astaxanthin metabolic process The chemical reactions and pathways involving astaxanthin. go-plus.json astaxanthin metabolism http://purl.obolibrary.org/obo/GO_1901813 GO:1901814 biolink:BiologicalProcess astaxanthin catabolic process The chemical reactions and pathways resulting in the breakdown of astaxanthin. go-plus.json astaxanthin breakdown|astaxanthin catabolism|astaxanthin degradation http://purl.obolibrary.org/obo/GO_1901814 GO:1901811 biolink:BiologicalProcess beta-carotene catabolic process The chemical reactions and pathways resulting in the breakdown of beta-carotene. go-plus.json beta-carotene breakdown|beta-carotene catabolism|beta-carotene degradation http://purl.obolibrary.org/obo/GO_1901811 GO:1901812 biolink:BiologicalProcess beta-carotene biosynthetic process The chemical reactions and pathways resulting in the formation of beta-carotene. go-plus.json beta-carotene anabolism|beta-carotene synthesis|beta-carotene formation|beta-carotene biosynthesis http://purl.obolibrary.org/obo/GO_1901812 GO:1901810 biolink:BiologicalProcess beta-carotene metabolic process The chemical reactions and pathways involving beta-carotene. go-plus.json beta-carotene metabolism http://purl.obolibrary.org/obo/GO_1901810 CHEBI:85550 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85550 chebi_ph7_3 CHEBI:85551 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchola-1,4-dien-22-oate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85551 chebi_ph7_3 CHEBI:85552 biolink:ChemicalSubstance 15-dehydroprostaglandin A1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85552 CHEBI:85553 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85553 chebi_ph7_3 CHEBI:85554 biolink:ChemicalSubstance (2E,4E,8Z,11Z,14Z)-icosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85554 CHEBI:36555 biolink:ChemicalSubstance N-acetylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36555 CHEBI:85555 biolink:ChemicalSubstance (2E,4Z)-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85555 CHEBI:85556 biolink:ChemicalSubstance trans,trans-2,4-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85556 CHEBI:85557 biolink:ChemicalSubstance trans-3-cis-5-octadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85557 CHEBI:36559 biolink:ChemicalSubstance 3-hydroxyanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36559 chebi_ph7_3 CHEBI:85559 biolink:ChemicalSubstance (3E,5Z)-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85559 CHEBI:36557 biolink:ChemicalSubstance N-methylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36557 chebi_ph7_3 GO:0060700 biolink:BiologicalProcess regulation of ribonuclease activity Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0060700 GO:0060701 biolink:BiologicalProcess negative regulation of ribonuclease activity Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0060701 CHEBI:36558 biolink:ChemicalSubstance 3-hydroxy-4-methylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36558 chebi_ph7_3 GO:0060702 biolink:BiologicalProcess negative regulation of endoribonuclease activity Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. go-plus.json http://purl.obolibrary.org/obo/GO_0060702 GO:0060703 biolink:MolecularActivity deoxyribonuclease inhibitor activity Binds to and stops, prevents or reduces the activity of deoxyribonuclease. go-plus.json DNase inhibitor activity http://purl.obolibrary.org/obo/GO_0060703 GO:0060704 biolink:BiologicalProcess acinar cell differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060704 GO:0060705 biolink:BiologicalProcess neuron differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060705 NCBITaxon:2100760 biolink:OrganismalEntity Saccharolobus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2100760 GO:0060706 biolink:BiologicalProcess cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0060706 GO:0060707 biolink:BiologicalProcess trophoblast giant cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua. go-plus.json http://purl.obolibrary.org/obo/GO_0060707 GO:0060708 biolink:BiologicalProcess spongiotrophoblast differentiation The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. go-plus.json spongiotrophoblast cell differentiation http://purl.obolibrary.org/obo/GO_0060708 GO:1901819 biolink:BiologicalProcess alpha-zeacarotene metabolic process The chemical reactions and pathways involving alpha-zeacarotene. go-plus.json alpha-zeacarotene metabolism http://purl.obolibrary.org/obo/GO_1901819 GO:0060709 biolink:BiologicalProcess glycogen cell differentiation involved in embryonic placenta development The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer. go-plus.json http://purl.obolibrary.org/obo/GO_0060709 CHEBI:36550 biolink:ChemicalSubstance sorbate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36550 chebi_ph7_3 GO:1901828 biolink:BiologicalProcess zeaxanthin bis(beta-D-glucoside) metabolic process The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside). go-plus.json zeaxanthin bis(beta-D-glucoside) metabolism|zeaxanthin diglucoside metabolism http://purl.obolibrary.org/obo/GO_1901828 GO:1901829 biolink:BiologicalProcess zeaxanthin bis(beta-D-glucoside) catabolic process The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside). go-plus.json zeaxanthin bis(beta-D-glucoside) degradation|zeaxanthin bis(beta-D-glucoside) breakdown|zeaxanthin bis(beta-D-glucoside) catabolism|zeaxanthin diglucoside degradation|zeaxanthin diglucoside catabolism|zeaxanthin diglucoside breakdown http://purl.obolibrary.org/obo/GO_1901829 GO:1901826 biolink:BiologicalProcess zeaxanthin catabolic process The chemical reactions and pathways resulting in the breakdown of zeaxanthin. go-plus.json zeaxanthin degradation|zeaxanthin breakdown|zeaxanthin catabolism http://purl.obolibrary.org/obo/GO_1901826 GO:1901827 biolink:BiologicalProcess zeaxanthin biosynthetic process The chemical reactions and pathways resulting in the formation of zeaxanthin. go-plus.json zeaxanthin biosynthesis|zeaxanthin anabolism|zeaxanthin synthesis|zeaxanthin formation http://purl.obolibrary.org/obo/GO_1901827 GO:1901824 biolink:BiologicalProcess delta-carotene biosynthetic process The chemical reactions and pathways resulting in the formation of delta-carotene. go-plus.json delta-carotene anabolism|delta-carotene synthesis|delta-carotene formation|delta-carotene biosynthesis http://purl.obolibrary.org/obo/GO_1901824 GO:1901825 biolink:BiologicalProcess zeaxanthin metabolic process The chemical reactions and pathways involving zeaxanthin. go-plus.json zeaxanthin metabolism http://purl.obolibrary.org/obo/GO_1901825 GO:1901822 biolink:BiologicalProcess delta-carotene metabolic process The chemical reactions and pathways involving delta-carotene. go-plus.json delta-carotene metabolism http://purl.obolibrary.org/obo/GO_1901822 GO:1901823 biolink:BiologicalProcess delta-carotene catabolic process The chemical reactions and pathways resulting in the breakdown of delta-carotene. go-plus.json delta-carotene degradation|delta-carotene breakdown|delta-carotene catabolism http://purl.obolibrary.org/obo/GO_1901823 GO:1901820 biolink:BiologicalProcess alpha-zeacarotene catabolic process The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene. go-plus.json alpha-zeacarotene breakdown|alpha-zeacarotene catabolism|alpha-zeacarotene degradation http://purl.obolibrary.org/obo/GO_1901820 GO:1901821 biolink:BiologicalProcess alpha-zeacarotene biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-zeacarotene. go-plus.json alpha-zeacarotene anabolism|alpha-zeacarotene biosynthesis|alpha-zeacarotene synthesis|alpha-zeacarotene formation http://purl.obolibrary.org/obo/GO_1901821 CHEBI:36528 biolink:ChemicalSubstance alpha-Neup5NAc-(2->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_36528 CHEBI:36529 biolink:ChemicalSubstance aristolochene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36529 CHEBI:85586 biolink:ChemicalSubstance glutathione S-sulfinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85586 chebi_ph7_3 CHEBI:85587 biolink:ChemicalSubstance 9-hydroperoxy-10E-octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85587 CHEBI:36522 biolink:ChemicalSubstance eudesmane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36522 chebi_ph7_3 CHEBI:36523 biolink:ChemicalSubstance humulane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36523 chebi_ph7_3 CHEBI:85589 biolink:ChemicalSubstance 10-hydroperoxy-8E-octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85589 CHEBI:36520 biolink:ChemicalSubstance oligoglycosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36520 GO:0060730 biolink:BiologicalProcess regulation of intestinal epithelial structure maintenance Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0060730 CHEBI:36521 biolink:ChemicalSubstance eremophilane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36521 chebi_ph7_3 GO:0060731 biolink:BiologicalProcess positive regulation of intestinal epithelial structure maintenance Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0060731 CHEBI:36526 biolink:ChemicalSubstance acidic glycosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36526 GO:0060732 biolink:BiologicalProcess positive regulation of inositol phosphate biosynthetic process Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. go-plus.json http://purl.obolibrary.org/obo/GO_0060732 CHEBI:36527 biolink:ChemicalSubstance glycosylsphingoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36527 GO:0060733 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060733 GO:0060734 biolink:BiologicalProcess regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress. go-plus.json regulation of eIF2 alpha phosphorylation by ER stress|regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress|regulation of ER stress-induced eIF2 alpha phosphorylation http://purl.obolibrary.org/obo/GO_0060734 GO:0060735 biolink:BiologicalProcess regulation of eIF2 alpha phosphorylation by dsRNA Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA. go-plus.json regulation of eIF2 alpha phosphorylation by double-stranded RNA|regulation of eIF2 alpha phosphorylation by PKR http://purl.obolibrary.org/obo/GO_0060735 GO:0060736 biolink:BiologicalProcess prostate gland growth The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060736 GO:0060737 biolink:BiologicalProcess prostate gland morphogenetic growth The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. go-plus.json prostate gland growth involved in morphogenesis http://purl.obolibrary.org/obo/GO_0060737 GO:0060738 biolink:BiologicalProcess epithelial-mesenchymal signaling involved in prostate gland development Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time. go-plus.json epithelial-mesenchymal signalling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060738 GO:0060739 biolink:BiologicalProcess mesenchymal-epithelial cell signaling involved in prostate gland development Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time. go-plus.json mesenchymal-epithelial cell signalling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060739 GO:1901839 biolink:BiologicalProcess regulation of RNA polymerase I regulatory region sequence-specific DNA binding Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_1901839 GO:1901837 biolink:BiologicalProcess negative regulation of transcription of nucleolar large rRNA by RNA polymerase I Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I. go-plus.json negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down-regulation of transcription of nuclear rRNA large Pol I transcript|negative regulation of transcription of nuclear rRNA large Pol I transcript|down regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|downregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|downregulation of transcription of nuclear rRNA large Pol I transcript|down regulation of transcription of nuclear rRNA large Pol I transcript|down-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|inhibition of transcription of nuclear rRNA large Pol I transcript|inhibition of transcription of nuclear large rRNA transcript from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_1901837 GO:1901838 biolink:BiologicalProcess positive regulation of transcription of nucleolar large rRNA by RNA polymerase I Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I. go-plus.json positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|upregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|activation of transcription of nuclear rRNA large Pol I transcript|positive regulation of transcription of nuclear rRNA large Pol I transcript|up regulation of transcription of nuclear rRNA large Pol I transcript|up regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|activation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|upregulation of transcription of nuclear rRNA large Pol I transcript|up-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|up-regulation of transcription of nuclear rRNA large Pol I transcript http://purl.obolibrary.org/obo/GO_1901838 GO:1901835 biolink:BiologicalProcess positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA. go-plus.json activation of deadenylation-independent decapping of nuclear mRNA|up regulation of deadenylylation-independent decapping|up-regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|positive regulation of deadenylylation-independent decapping|up-regulation of deadenylation-independent decapping of nuclear mRNA|activation of deadenylylation-independent decapping|upregulation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylation-independent decapping of nuclear mRNA|up-regulation of deadenylylation-independent decapping|up regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|activation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylylation-independent decapping|up regulation of deadenylation-independent decapping of nuclear mRNA|positive regulation of deadenylation-independent decapping of nuclear mRNA http://purl.obolibrary.org/obo/GO_1901835 GO:1901836 biolink:BiologicalProcess regulation of transcription of nucleolar large rRNA by RNA polymerase I Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I. go-plus.json regulation of transcription of nuclear rRNA large Pol I transcript|regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_1901836 GO:1901833 biolink:BiologicalProcess all-trans-neoxanthin biosynthetic process The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin. go-plus.json neoxanthin synthesis|neoxanthin formation|all-trans-neoxanthin biosynthesis|all-trans-neoxanthin anabolism|all-trans-neoxanthin synthesis|all-trans-neoxanthin formation|neoxanthin biosynthetic process|neoxanthin biosynthesis|neoxanthin anabolism http://purl.obolibrary.org/obo/GO_1901833 GO:1901834 biolink:BiologicalProcess regulation of deadenylation-independent decapping of nuclear-transcribed mRNA Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA. go-plus.json regulation of deadenylylation-independent decapping|regulation of deadenylation-independent decapping of nuclear mRNA http://purl.obolibrary.org/obo/GO_1901834 GO:1901831 biolink:BiologicalProcess all-trans-neoxanthin metabolic process The chemical reactions and pathways involving all-trans-neoxanthin. go-plus.json all-trans-neoxanthin metabolism|neoxanthin metabolic process|neoxanthin metabolism http://purl.obolibrary.org/obo/GO_1901831 GO:0045105 biolink:BiologicalProcess intermediate filament polymerization or depolymerization Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament. go-plus.json http://purl.obolibrary.org/obo/GO_0045105 GO:1901832 biolink:BiologicalProcess all-trans-neoxanthin catabolic process The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin. go-plus.json all-trans-neoxanthin degradation|all-trans-neoxanthin catabolism|all-trans-neoxanthin breakdown|neoxanthin degradation|neoxanthin catabolism|neoxanthin breakdown|neoxanthin catabolic process http://purl.obolibrary.org/obo/GO_1901832 GO:0045106 biolink:BiologicalProcess intermediate filament depolymerization Disassembly of intermediate filaments by the removal of component monomers from a filament. go-plus.json http://purl.obolibrary.org/obo/GO_0045106 CHEBI:36539 biolink:ChemicalSubstance kaurane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36539 chebi_ph7_3 GO:0045103 biolink:BiologicalProcess intermediate filament-based process Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0045103 GO:0045104 biolink:BiologicalProcess intermediate filament cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. go-plus.json intermediate filament cytoskeleton organisation|intermediate filament cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0045104 GO:1901830 biolink:BiologicalProcess zeaxanthin bis(beta-D-glucoside) biosynthetic process The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside). go-plus.json zeaxanthin bis(beta-D-glucoside) synthesis|zeaxanthin bis(beta-D-glucoside) formation|zeaxanthin diglucoside biosynthesis|zeaxanthin diglucoside anabolism|zeaxanthin diglucoside synthesis|zeaxanthin diglucoside formation|zeaxanthin bis(beta-D-glucoside) biosynthesis|zeaxanthin bis(beta-D-glucoside) anabolism http://purl.obolibrary.org/obo/GO_1901830 GO:0045101 biolink:CellularComponent obsolete glial fibrillary acidic protein OBSOLETE. Glial fibrillary acidic protein forms filaments in the glial cells that surround neurons and in astrocytes. go-plus.json glial fibrillary acidic protein|GFAP http://purl.obolibrary.org/obo/GO_0045101 GO:0045102 biolink:CellularComponent obsolete peripherin OBSOLETE. Peripherin is a type III intermediate filament protein found in neurons of the peripheral nervous system. go-plus.json peripherin http://purl.obolibrary.org/obo/GO_0045102 CHEBI:85575 biolink:ChemicalSubstance 3,17-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85575 chebi_ph7_3 GO:0045100 biolink:CellularComponent obsolete desmin OBSOLETE. A type of intermediate filament. go-plus.json desmin http://purl.obolibrary.org/obo/GO_0045100 CHEBI:85576 biolink:ChemicalSubstance 3,4,17-trihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85576 chebi_ph7_3 CHEBI:36534 biolink:ChemicalSubstance 2,6,10-trimethyldodeca-2,6,10-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36534 chebi_ph7_3 CHEBI:36531 biolink:ChemicalSubstance (2Z,4E)-5-carboxy-2,3,5-trichloropenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36531 GO:0060720 biolink:BiologicalProcess spongiotrophoblast cell proliferation The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer. go-plus.json http://purl.obolibrary.org/obo/GO_0060720 GO:0045109 biolink:BiologicalProcess intermediate filament organization Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. go-plus.json intermediate filament organisation http://purl.obolibrary.org/obo/GO_0045109 CHEBI:36538 biolink:ChemicalSubstance 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36538 GO:0060721 biolink:BiologicalProcess regulation of spongiotrophoblast cell proliferation Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0060721 GO:0060722 biolink:BiologicalProcess cell proliferation involved in embryonic placenta development The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0060722 GO:0045107 biolink:BiologicalProcess intermediate filament polymerization Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain. go-plus.json http://purl.obolibrary.org/obo/GO_0045107 GO:0045108 biolink:BiologicalProcess regulation of intermediate filament polymerization or depolymerization Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases. go-plus.json http://purl.obolibrary.org/obo/GO_0045108 GO:0060723 biolink:BiologicalProcess regulation of cell proliferation involved in embryonic placenta development Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. go-plus.json http://purl.obolibrary.org/obo/GO_0060723 GO:0060724 biolink:MolecularActivity coreceptor activity involved in epidermal growth factor receptor signaling pathway Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway. go-plus.json coreceptor activity involved in epidermal growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060724 GO:0060725 biolink:BiologicalProcess regulation of coreceptor activity Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0060725 GO:0060726 biolink:BiologicalProcess regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. go-plus.json regulation of Neu/ErbB-2 receptor activity|regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060726 GO:0060727 biolink:BiologicalProcess positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. go-plus.json positive regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|positive regulation of Neu/ErbB-2 receptor activity http://purl.obolibrary.org/obo/GO_0060727 GO:0060728 biolink:BiologicalProcess negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. go-plus.json negative regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|negative regulation of Neu/ErbB-2 receptor activity http://purl.obolibrary.org/obo/GO_0060728 GO:0060729 biolink:BiologicalProcess intestinal epithelial structure maintenance A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. go-plus.json maintenance of intestinal epithelium|epithelial structure maintenance of intestine http://purl.obolibrary.org/obo/GO_0060729 CHEBI:36530 biolink:ChemicalSubstance cedrane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36530 chebi_ph7_3 CHEBI:141005 biolink:ChemicalSubstance (6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_141005 chebi_ph7_3 GO:0035782 biolink:BiologicalProcess mature natural killer cell chemotaxis The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules. go-plus.json activated natural killer cell chemotaxis http://purl.obolibrary.org/obo/GO_0035782 GO:0035783 biolink:BiologicalProcess CD4-positive, alpha-beta T cell costimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation. go-plus.json CD4-positive, alpha beta T cell costimulation http://purl.obolibrary.org/obo/GO_0035783 GO:0035784 biolink:BiologicalProcess nickel cation homeostasis Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell. go-plus.json nickel homeostasis http://purl.obolibrary.org/obo/GO_0035784 GO:0035785 biolink:BiologicalProcess cellular nickel ion homeostasis Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell. go-plus.json cellular nickel homeostasis http://purl.obolibrary.org/obo/GO_0035785 GO:0035786 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035786 GO:0035787 biolink:BiologicalProcess cell migration involved in kidney development The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. go-plus.json http://purl.obolibrary.org/obo/GO_0035787 GO:0035788 biolink:BiologicalProcess cell migration involved in metanephros development The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. go-plus.json cell migration involved in metanephric kidney development http://purl.obolibrary.org/obo/GO_0035788 GO:0035789 biolink:BiologicalProcess metanephric mesenchymal cell migration The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros. go-plus.json metanephric mesenchyme chemotaxis http://purl.obolibrary.org/obo/GO_0035789 GO:0035780 biolink:BiologicalProcess CD80 biosynthetic process The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival. go-plus.json CD80 biosynthesis|CD80 anabolism|CD80 synthesis|CD80 formation http://purl.obolibrary.org/obo/GO_0035780 GO:0035781 biolink:BiologicalProcess CD86 biosynthetic process The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival. go-plus.json CD86 anabolism|CD86 synthesis|CD86 formation|CD86 biosynthesis http://purl.obolibrary.org/obo/GO_0035781 GO:0035779 biolink:BiologicalProcess angioblast cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). go-plus.json angioblastic mesenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0035779 GO:0035771 biolink:BiologicalProcess interleukin-4-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-4-mediated signalling pathway|IL-4-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0035771 GO:0035772 biolink:BiologicalProcess interleukin-13-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-13-mediated signalling pathway|IL-13-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0035772 GO:0035773 biolink:BiologicalProcess insulin secretion involved in cellular response to glucose stimulus The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. go-plus.json insulin secretion involved in cellular response to glucose http://purl.obolibrary.org/obo/GO_0035773 GO:0035774 biolink:BiologicalProcess positive regulation of insulin secretion involved in cellular response to glucose stimulus Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. go-plus.json positive regulation of insulin secretion in response to glucose http://purl.obolibrary.org/obo/GO_0035774 GO:0035775 biolink:BiologicalProcess pronephric glomerulus morphogenesis The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. go-plus.json http://purl.obolibrary.org/obo/GO_0035775 GO:0035776 biolink:BiologicalProcess pronephric proximal tubule development The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. go-plus.json http://purl.obolibrary.org/obo/GO_0035776 GO:0035777 biolink:BiologicalProcess pronephric distal tubule development The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. go-plus.json http://purl.obolibrary.org/obo/GO_0035777 GO:0035778 biolink:BiologicalProcess pronephric nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0035778 GO:0035770 biolink:CellularComponent ribonucleoprotein granule A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions. go-plus.json mRNP granule|RNP granule|RNA granule http://purl.obolibrary.org/obo/GO_0035770 GO:0035768 biolink:BiologicalProcess endothelial cell chemotaxis to fibroblast growth factor The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF). go-plus.json http://purl.obolibrary.org/obo/GO_0035768 GO:0035769 biolink:BiologicalProcess B cell chemotaxis across high endothelial venule The movement of a B cell to cross a high endothelial venule in response to an external stimulus. go-plus.json B-cell chemotaxis across high endothelial venule http://purl.obolibrary.org/obo/GO_0035769 CHEBI:131657 biolink:ChemicalSubstance cholane derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_131657 GO:0035760 biolink:BiologicalProcess cytoplasmic polyadenylation-dependent rRNA catabolic process The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate. go-plus.json cytoplasmic poly(A)-dependent rRNA catabolic process http://purl.obolibrary.org/obo/GO_0035760 GO:0035761 biolink:BiologicalProcess dorsal motor nucleus of vagus nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0035761 GO:0035762 biolink:BiologicalProcess dorsal motor nucleus of vagus nerve morphogenesis The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form. go-plus.json http://purl.obolibrary.org/obo/GO_0035762 CHEBI:131650 biolink:ChemicalSubstance phosphinomethylisomalate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131650 chebi_ph7_3 GO:0035763 biolink:BiologicalProcess dorsal motor nucleus of vagus nerve structural organization The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. go-plus.json dorsal motor nucleus of vagus nerve structural organisation http://purl.obolibrary.org/obo/GO_0035763 CHEBI:131651 biolink:ChemicalSubstance 2-(phosphinatomethylidene)succinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131651 chebi_ph7_3 GO:0035764 biolink:BiologicalProcess dorsal motor nucleus of vagus nerve formation The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0035764 CHEBI:131652 biolink:ChemicalSubstance cholestanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131652 chebi_ph7_3 GO:0035765 biolink:BiologicalProcess motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0035765 GO:0035766 biolink:BiologicalProcess cell chemotaxis to fibroblast growth factor The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF). go-plus.json http://purl.obolibrary.org/obo/GO_0035766 GO:0035767 biolink:BiologicalProcess endothelial cell chemotaxis The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_0035767 NCBITaxon:515635 biolink:OrganismalEntity Dictyoglomus turgidum DSM 6724 go-plus.json Dictyoglomus turgidum strain DSM 6724|Dictyoglomus turgidum str. DSM 6724 http://purl.obolibrary.org/obo/NCBITaxon_515635 GO:0035757 biolink:MolecularActivity chemokine (C-C motif) ligand 19 binding Binding to chemokine (C-C motif) ligand 19. go-plus.json CCL19 binding http://purl.obolibrary.org/obo/GO_0035757 GO:0035758 biolink:MolecularActivity chemokine (C-C motif) ligand 21 binding Binding to chemokine (C-C motif) ligand 21. go-plus.json CCL21 binding http://purl.obolibrary.org/obo/GO_0035758 GO:0035759 biolink:BiologicalProcess mesangial cell-matrix adhesion The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0035759 GO:0035750 biolink:BiologicalProcess protein localization to myelin sheath abaxonal region Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon. go-plus.json protein localisation to myelin sheath abaxonal region http://purl.obolibrary.org/obo/GO_0035750 GO:0035751 biolink:BiologicalProcess regulation of lysosomal lumen pH Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. go-plus.json http://purl.obolibrary.org/obo/GO_0035751 GO:0035752 biolink:BiologicalProcess lysosomal lumen pH elevation Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. go-plus.json lysosome pH elevation http://purl.obolibrary.org/obo/GO_0035752 GO:0035753 biolink:BiologicalProcess maintenance of DNA trinucleotide repeats Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs. go-plus.json http://purl.obolibrary.org/obo/GO_0035753 CHEBI:61505 biolink:ChemicalSubstance cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_61505 GO:0035754 biolink:BiologicalProcess B cell chemotaxis The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_0035754 GO:0035755 biolink:MolecularActivity cardiolipin hydrolase activity Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA). Reactome:R-HSA-8954398 go-plus.json http://purl.obolibrary.org/obo/GO_0035755 CHEBI:61502 biolink:ChemicalSubstance heptosyl-(KDO)2-lipid A(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61502 chebi_ph7_3 GO:0035756 biolink:BiologicalProcess transepithelial migration of symbiont in host The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json migration of symbiont within host by transepithelial trafficking|migration in host through an epithelial cell layer|transmigration of symbiont in host http://purl.obolibrary.org/obo/GO_0035756 CHEBI:61508 biolink:ChemicalSubstance gamma-glutamyl-gamma-aminobutyraldehyde zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61508 chebi_ph7_3 CHEBI:61509 biolink:ChemicalSubstance N-acetyl-L-2-aminoadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61509 chebi_ph7_3 CHEBI:61506 biolink:ChemicalSubstance ADP-L-glycero-beta-D-manno-heptose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61506 chebi_ph7_3 CHEBI:61507 biolink:ChemicalSubstance (heptosyl)2-(KDO)2-lipid A(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61507 chebi_ph7_3 GO:0035746 biolink:BiologicalProcess granzyme A production The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0035746 gocheck_do_not_annotate CHEBI:131634 biolink:ChemicalSubstance pregnane derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_131634 GO:0035747 biolink:BiologicalProcess natural killer cell chemotaxis The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_0035747 CHEBI:131635 biolink:ChemicalSubstance estrane derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_131635 GO:0035748 biolink:CellularComponent myelin sheath abaxonal region The region of the myelin sheath furthest from the axon. go-plus.json http://purl.obolibrary.org/obo/GO_0035748 CHEBI:131636 biolink:ChemicalSubstance GDP-4-amino-3,4,6-trideoxy-alpha-D-threo-hex-3-enopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131636 chebi_ph7_3 GO:0035749 biolink:CellularComponent myelin sheath adaxonal region The region of the myelin sheath nearest to the axon. go-plus.json http://purl.obolibrary.org/obo/GO_0035749 CHEBI:131639 biolink:ChemicalSubstance GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131639 chebi_ph7_3 CHEBI:61511 biolink:ChemicalSubstance N-acetyl-L-2-aminoadipate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_61511 chebi_ph7_3 CHEBI:61512 biolink:ChemicalSubstance N(2)-acetyl-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61512 chebi_ph7_3 GO:0035740 biolink:BiologicalProcess CD8-positive, alpha-beta T cell proliferation The expansion of a CD8-positive, alpha-beta T cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0035740 CHEBI:61510 biolink:ChemicalSubstance N-acetyl-L-2-aminoadipate 6-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61510 chebi_ph7_3 GO:0035741 biolink:BiologicalProcess activated CD4-positive, alpha-beta T cell proliferation The expansion of an activated CD4-positive, alpha-beta T cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0035741 GO:0035742 biolink:BiologicalProcess activated CD8-positive, alpha-beta T cell proliferation The expansion of an activated CD8-positive, alpha-beta T cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0035742 CHEBI:61515 biolink:ChemicalSubstance N-acetyl-L-2-aminoadipic acid semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_61515 GO:0035743 biolink:BiologicalProcess CD4-positive, alpha-beta T cell cytokine production Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell. go-plus.json http://purl.obolibrary.org/obo/GO_0035743 gocheck_do_not_annotate GO:0035744 biolink:BiologicalProcess T-helper 1 cell cytokine production Any process that contributes to cytokine production by a T-helper 1 cell. go-plus.json Th1 cell cytokine production http://purl.obolibrary.org/obo/GO_0035744 gocheck_do_not_annotate CHEBI:61513 biolink:ChemicalSubstance gamma-butyrobetainyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61513 chebi_ph7_3 CHEBI:131632 biolink:ChemicalSubstance lanostane derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_131632 GO:0035745 biolink:BiologicalProcess T-helper 2 cell cytokine production Any process that contributes to cytokine production by a T-helper 2 cell. go-plus.json Th2 cell cytokine production http://purl.obolibrary.org/obo/GO_0035745 gocheck_do_not_annotate CHEBI:61519 biolink:ChemicalSubstance D-psicose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61519 chebi_ph7_3 CHEBI:61517 biolink:ChemicalSubstance gamma-butyrobetainyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61517 GO:0035735 biolink:BiologicalProcess intraciliary transport involved in cilium assembly The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. Reactome:R-HSA-5620924.2 go-plus.json intraflagellar transport involved in cilium morphogenesis|intraflagellar transport|intraciliary transport involved in cilium morphogenesis http://purl.obolibrary.org/obo/GO_0035735 GO:0035736 biolink:BiologicalProcess cell proliferation involved in compound eye morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0035736 CHEBI:131647 biolink:ChemicalSubstance androstane sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131647 GO:0035737 biolink:BiologicalProcess injection of substance in to other organism The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes. go-plus.json http://purl.obolibrary.org/obo/GO_0035737 GO:0035738 biolink:BiologicalProcess envenomation resulting in modulation of process in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism. go-plus.json envenomation resulting in modification of morphology or physiology of other organism http://purl.obolibrary.org/obo/GO_0035738 GO:0035739 biolink:BiologicalProcess CD4-positive, alpha-beta T cell proliferation The expansion of a CD4-positive, alpha-beta T cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0035739 CHEBI:61522 biolink:ChemicalSubstance (KDO)2-(palmitoleoyl-myristoyl)-lipid A(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61522 chebi_ph7_3 CHEBI:61523 biolink:ChemicalSubstance (heptosyl)2-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_61523 CHEBI:61520 biolink:ChemicalSubstance (KDO)2-(palmitoleoyl)-lipid IVA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61520 chebi_ph7_3 CHEBI:61521 biolink:ChemicalSubstance gamma-glutamyl-gamma-aminobutyraldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_61521 GO:0035730 biolink:MolecularActivity S-nitrosoglutathione binding Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems. go-plus.json GSNO binding http://purl.obolibrary.org/obo/GO_0035730 GO:0035731 biolink:MolecularActivity dinitrosyl-iron complex binding Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO. go-plus.json DNIC binding|DNDGIC binding|dinitrosyl-diglutathionyl-iron complex binding http://purl.obolibrary.org/obo/GO_0035731 CHEBI:61526 biolink:ChemicalSubstance (E)-hexadec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61526 chebi_ph7_3 GO:0035732 biolink:BiologicalProcess nitric oxide storage The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins. go-plus.json NO storage http://purl.obolibrary.org/obo/GO_0035732 CHEBI:61527 biolink:ChemicalSubstance D-fructofuranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61527 chebi_ph7_3 GO:0035733 biolink:BiologicalProcess hepatic stellate cell activation A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0035733 CHEBI:61524 biolink:ChemicalSubstance (KDO)2-(lauroyl)-lipid IVA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61524 chebi_ph7_3 CHEBI:131643 biolink:ChemicalSubstance ketocholestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_131643 GO:0035734 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035734 CHEBI:61528 biolink:ChemicalSubstance heptosyl-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_61528 CHEBI:61529 biolink:ChemicalSubstance alpha-L-Fucp-(1->2)-beta-D-Galp go-plus.json http://purl.obolibrary.org/obo/CHEBI_61529 chebi_ph7_3 GO:0035724 biolink:BiologicalProcess CD24 biosynthetic process The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation. go-plus.json CD24 biosynthesis|CD24 anabolism|CD24 synthesis|CD24 formation http://purl.obolibrary.org/obo/GO_0035724 GO:0035725 biolink:BiologicalProcess sodium ion transmembrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json sodium ion membrane transport http://purl.obolibrary.org/obo/GO_0035725 GO:0035726 biolink:BiologicalProcess common myeloid progenitor cell proliferation The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage. go-plus.json http://purl.obolibrary.org/obo/GO_0035726 GO:0035727 biolink:MolecularActivity lysophosphatidic acid binding Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors. go-plus.json LPA binding http://purl.obolibrary.org/obo/GO_0035727 GO:0035728 biolink:BiologicalProcess response to hepatocyte growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus. go-plus.json response to HGF stimulus|response to hepatocyte growth factor stimulus http://purl.obolibrary.org/obo/GO_0035728 GO:0035729 biolink:BiologicalProcess cellular response to hepatocyte growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus. go-plus.json cellular response to HGF stimulus http://purl.obolibrary.org/obo/GO_0035729 CHEBI:131617 biolink:ChemicalSubstance 18-oxoresolvin E1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_131617 CHEBI:61530 biolink:ChemicalSubstance ADP-L-glycero-beta-D-manno-heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61530 CHEBI:131619 biolink:ChemicalSubstance C27-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131619 CHEBI:61533 biolink:ChemicalSubstance alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61533 NCBITaxon:118964 biolink:OrganismalEntity Deinococcales go-plus.json radio-resistant micrococci http://purl.obolibrary.org/obo/NCBITaxon_118964 CHEBI:85501 biolink:ChemicalSubstance N(4)-(beta-D-glucosyl)-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85501 chebi_ph7_3 GO:0035720 biolink:BiologicalProcess intraciliary anterograde transport The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins. go-plus.json intraflagellar anterograde transport http://purl.obolibrary.org/obo/GO_0035720 NCBITaxon:118968 biolink:OrganismalEntity Coxiellaceae go-plus.json Coxiella group http://purl.obolibrary.org/obo/NCBITaxon_118968 CHEBI:85504 biolink:ChemicalSubstance 2,6-dimethylheptanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85504 CHEBI:61537 biolink:ChemicalSubstance UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61537 GO:0035721 biolink:BiologicalProcess intraciliary retrograde transport The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins. go-plus.json intraflagellar retrograde transport http://purl.obolibrary.org/obo/GO_0035721 NCBITaxon:118969 biolink:OrganismalEntity Legionellales go-plus.json Legionellaceae group http://purl.obolibrary.org/obo/NCBITaxon_118969 GO:0035722 biolink:BiologicalProcess interleukin-12-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-12-mediated signaling pathway|interleukin-12-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0035722 CHEBI:131610 biolink:ChemicalSubstance O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_131610 chebi_ph7_3 GO:0035723 biolink:BiologicalProcess interleukin-15-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-15-mediated signaling pathway|interleukin-15-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0035723 CHEBI:85507 biolink:ChemicalSubstance GDP-alpha-D-mannuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85507 CHEBI:85508 biolink:ChemicalSubstance (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85508 CHEBI:85509 biolink:ChemicalSubstance 3-amino-N-(trans-3-carbamoyloxirane-2-carbonyl)-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85509 GO:0035713 biolink:BiologicalProcess response to nitrogen dioxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus. go-plus.json response to NO2 http://purl.obolibrary.org/obo/GO_0035713 GO:0035714 biolink:BiologicalProcess cellular response to nitrogen dioxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus. go-plus.json cellular response to NO2 http://purl.obolibrary.org/obo/GO_0035714 GO:0035715 biolink:MolecularActivity chemokine (C-C motif) ligand 2 binding Binding to chemokine (C-C motif) ligand 2. go-plus.json CCL2 binding http://purl.obolibrary.org/obo/GO_0035715 GO:0035716 biolink:MolecularActivity chemokine (C-C motif) ligand 12 binding Binding to chemokine (C-C motif) ligand 12. go-plus.json CCL12 binding http://purl.obolibrary.org/obo/GO_0035716 CHEBI:61540 biolink:ChemicalSubstance palmitoleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61540 chebi_ph7_3 GO:0035717 biolink:MolecularActivity chemokine (C-C motif) ligand 7 binding Binding to chemokine (C-C motif) ligand 7. go-plus.json CCL7 binding http://purl.obolibrary.org/obo/GO_0035717 GO:0035718 biolink:MolecularActivity macrophage migration inhibitory factor binding Binding to the cytokine, macrophage migration inhibitory factor. go-plus.json MIF binding http://purl.obolibrary.org/obo/GO_0035718 GO:0035719 biolink:BiologicalProcess tRNA import into nucleus The directed movement of tRNA from the cytoplasm to the nucleus. go-plus.json retrograde tRNA transport into nucleus|tRNA nuclear import http://purl.obolibrary.org/obo/GO_0035719 CHEBI:61543 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61543 CHEBI:61548 biolink:ChemicalSubstance D-glucopyranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61548 chebi_ph7_3 GO:0035710 biolink:BiologicalProcess CD4-positive, alpha-beta T cell activation The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json http://purl.obolibrary.org/obo/GO_0035710 CHEBI:131620 biolink:ChemicalSubstance C24-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131620 GO:0035711 biolink:BiologicalProcess T-helper 1 cell activation The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json Th1 cell activation http://purl.obolibrary.org/obo/GO_0035711 CHEBI:131621 biolink:ChemicalSubstance C19-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131621 GO:0035712 biolink:BiologicalProcess T-helper 2 cell activation The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json Th2 cell activation http://purl.obolibrary.org/obo/GO_0035712 CHEBI:131622 biolink:ChemicalSubstance steroidal acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131622 chebi_ph7_3 GO:0045075 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045075 GO:0070031 biolink:CellularComponent alphav-beta5 integrin-osteopontin complex A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin. go-plus.json ITGAV-ITGB5-SPP1 complex http://purl.obolibrary.org/obo/GO_0070031 GO:0045076 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045076 GO:0070032 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof). go-plus.json Vamp2-Snap25-Stx1a-Cplx1 complex|SNARE complex (Vamp2, Snap25, Stx1a, Cplx1) http://purl.obolibrary.org/obo/GO_0070032 GO:0045073 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045073 GO:0045074 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045074 GO:0070030 biolink:CellularComponent alphav-beta1 integrin-osteopontin complex A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin. go-plus.json ITGAV-ITGB1-SPP1 complex http://purl.obolibrary.org/obo/GO_0070030 GO:0045071 biolink:BiologicalProcess negative regulation of viral genome replication Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication. go-plus.json down regulation of viral genome replication|inhibition of viral genome replication|down-regulation of viral genome replication|downregulation of viral genome replication http://purl.obolibrary.org/obo/GO_0045071 GO:0045072 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045072 GO:0045070 biolink:BiologicalProcess positive regulation of viral genome replication Any process that activates or increases the frequency, rate or extent of viral genome replication. go-plus.json upregulation of viral genome replication|stimulation of viral genome replication|up-regulation of viral genome replication|activation of viral genome replication|up regulation of viral genome replication http://purl.obolibrary.org/obo/GO_0045070 GO:0045079 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045079 GO:0045077 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045077 GO:0045078 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045078 GO:0070039 biolink:MolecularActivity rRNA (guanosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine. Reactome:R-HSA-6793096|Reactome:R-HSA-6793122 go-plus.json http://purl.obolibrary.org/obo/GO_0070039 GO:0070037 biolink:MolecularActivity rRNA (pseudouridine) methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule. Reactome:R-HSA-6790906 go-plus.json http://purl.obolibrary.org/obo/GO_0070037 GO:0070038 biolink:MolecularActivity rRNA (pseudouridine-N3-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine. go-plus.json http://purl.obolibrary.org/obo/GO_0070038 GO:0070035 biolink:MolecularActivity obsolete purine NTP-dependent helicase activity OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix. go-plus.json http://purl.obolibrary.org/obo/GO_0070035 GO:0070036 biolink:MolecularActivity obsolete GTP-dependent helicase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix. go-plus.json http://purl.obolibrary.org/obo/GO_0070036 GO:0070033 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof). go-plus.json Vamp2-Snap25-Stx1a-Cplx2 complex|SNARE complex (Vamp2, Snap25, Stx1a, Cplx2) http://purl.obolibrary.org/obo/GO_0070033 GO:0070034 biolink:MolecularActivity telomerase RNA binding Binding to the telomerase RNA template. go-plus.json TERC binding http://purl.obolibrary.org/obo/GO_0070034 GO:0070020 biolink:CellularComponent obsolete transforming growth factor beta1-type II receptor complex OBSOLETE. A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer. go-plus.json TGF-beta receptor II-TGF-beta1 complex|TGF-beta1-type II receptor complex http://purl.obolibrary.org/obo/GO_0070020 GO:0045086 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045086 GO:0045087 biolink:BiologicalProcess innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Wikipedia:Innate_immune_system go-plus.json nonspecific immune response|innate immunity http://purl.obolibrary.org/obo/GO_0045087 GO:0070021 biolink:CellularComponent transforming growth factor beta ligand-receptor complex A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand. go-plus.json transforming growth factor beta1-type II receptor-type I receptor complex|TGFbeta2 ligand-receptor complex|TGFbeta1 ligand-receptor complex|TGF-beta1-type II receptor-type I receptor complex|TGFb ligand-receptor complex|TGF-beta2 ligand-receptor complex|TGF-beta1 ligand-receptor complex|TGF-beta ligand-receptor complex|TGFbeta1-beta2 ligand-receptor complex|TGFbeta ligand-receptor complex|TGF-beta1-beta2 ligand-receptor complex|TGF-beta 1:type II receptor:type I receptor complex|TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex http://purl.obolibrary.org/obo/GO_0070021 GO:0045084 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045084 GO:0045085 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045085 GO:0045082 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045082 GO:0045083 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045083 GO:0045080 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045080 PATO:0001908 biolink:OntologyClass multinucleate A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. go-plus.json http://purl.obolibrary.org/obo/PATO_0001908 GO:0045081 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045081 GO:0045088 biolink:BiologicalProcess regulation of innate immune response Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. go-plus.json http://purl.obolibrary.org/obo/GO_0045088 GO:0045089 biolink:BiologicalProcess positive regulation of innate immune response Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. go-plus.json upregulation of innate immune response|stimulation of innate immune response|up-regulation of innate immune response|up regulation of innate immune response http://purl.obolibrary.org/obo/GO_0045089 GO:0070028 biolink:BiologicalProcess obsolete regulation of transcription by carbon monoxide OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription. go-plus.json regulation of transcription by CO http://purl.obolibrary.org/obo/GO_0070028 GO:0045090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045090 GO:0070029 biolink:CellularComponent alphav-beta3 integrin-osteopontin complex A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin. go-plus.json ITGAV-ITGB3-SPP1 complex http://purl.obolibrary.org/obo/GO_0070029 GO:0070026 biolink:MolecularActivity nitric oxide binding Binding to nitric oxide (NO). go-plus.json NO binding|nitrogen monoxide binding|nitrosyl binding http://purl.obolibrary.org/obo/GO_0070026 GO:0070027 biolink:MolecularActivity carbon monoxide sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO). go-plus.json http://purl.obolibrary.org/obo/GO_0070027 GO:0070024 biolink:CellularComponent CD19-Vav-PIK3R1 complex A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K). go-plus.json CD19-Vav-PI 3-kinase (p85 subunit) complex http://purl.obolibrary.org/obo/GO_0070024 GO:0070025 biolink:MolecularActivity carbon monoxide binding Binding to carbon monoxide (CO). go-plus.json CO binding http://purl.obolibrary.org/obo/GO_0070025 UBERON:0037191 biolink:AnatomicalEntity wall of membranous labyrinth go-plus.json membranous labyrinth wall http://purl.obolibrary.org/obo/UBERON_0037191 GO:0070022 biolink:CellularComponent obsolete transforming growth factor beta receptor complex OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers. go-plus.json transforming growth factor beta receptor complex|TGF-beta receptor complex http://purl.obolibrary.org/obo/GO_0070022 GO:0070023 biolink:CellularComponent interleukin-12-interleukin-12 receptor complex A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer. go-plus.json IL12-IL12 receptor complex|IL12B-IL12RB1-IL12RB2 complex http://purl.obolibrary.org/obo/GO_0070023 GO:0070053 biolink:MolecularActivity thrombospondin receptor activity Combining with thrombospondin and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0070053 GO:0045097 biolink:CellularComponent obsolete basic/neutral keratin OBSOLETE. A type of intermediate filament. go-plus.json type II intermediate filament|basic/neutral keratin http://purl.obolibrary.org/obo/GO_0045097 GO:0070054 biolink:BiologicalProcess mRNA splicing, via endonucleolytic cleavage and ligation Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. go-plus.json cytosolic mRNA splicing http://purl.obolibrary.org/obo/GO_0070054 GO:0045098 biolink:CellularComponent type III intermediate filament A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments. go-plus.json desmin|glial fibrillary acidic protein|vimentin|peripherin|type III intermediate filament associated protein http://purl.obolibrary.org/obo/GO_0045098 GO:0045095 biolink:CellularComponent keratin filament A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. go-plus.json acidic keratin|basic/neutral keratin http://purl.obolibrary.org/obo/GO_0045095 GO:0070051 biolink:MolecularActivity fibrinogen binding Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0070051 GO:0045096 biolink:CellularComponent obsolete acidic keratin OBSOLETE. A type of intermediate filament. go-plus.json acidic keratin|type I intermediate filament http://purl.obolibrary.org/obo/GO_0045096 GO:0070052 biolink:MolecularActivity collagen V binding Binding to a type V collagen trimer. go-plus.json http://purl.obolibrary.org/obo/GO_0070052 GO:0045093 biolink:MolecularActivity obsolete interleukin-18 alpha subunit binding OBSOLETE. Binding to alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells. go-plus.json IL-18Ra binding http://purl.obolibrary.org/obo/GO_0045093 GO:0070050 biolink:BiologicalProcess neuron cellular homeostasis The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. go-plus.json neuron maintenance http://purl.obolibrary.org/obo/GO_0070050 GO:0045094 biolink:MolecularActivity obsolete interleukin-18 beta subunit binding OBSOLETE. Binding to beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a. go-plus.json IL-18Rb binding http://purl.obolibrary.org/obo/GO_0045094 UBERON:0013191 biolink:AnatomicalEntity ovarian cortex the layer of the ovarian stroma lying immediately beneath the tunica albuginea, composed of connective tissue cells and fibers, among which are scattered primary and secondary (antral) follicles in various stages of development; the cortex varies in thickness according to the age of the individual, becoming thinner with advancing years; included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte; the zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle; also in the cortex is the corpus luteum derived from the follicles. go-plus.json cortex of ovary|cortex ovarii (zona parenchymatosa) http://purl.obolibrary.org/obo/UBERON_0013191 UBERON:0013192 biolink:AnatomicalEntity ovarian medulla highly vascular stroma found in the center of the ovary that forms from embryonic mesenchyme and contains blood vessels, lymphatic vessels, and nerves; this stroma forms the tissue of the hilum by which the ovarian ligament is attached, and through which the blood vessels enter; it does not contain any ovarian follicles. go-plus.json medulla of ovary|zona vasculosa of Waldeyer|medulla ovarii (zona vasculosa) http://purl.obolibrary.org/obo/UBERON_0013192 GO:0045091 biolink:BiologicalProcess regulation of single stranded viral RNA replication via double stranded DNA intermediate Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate. go-plus.json regulation of retroviral genome replication http://purl.obolibrary.org/obo/GO_0045091 GO:0045092 biolink:CellularComponent interleukin-18 receptor complex A protein complex that binds interleukin-18; comprises an alpha and a beta subunit. go-plus.json IL-18 receptor complex http://purl.obolibrary.org/obo/GO_0045092 GO:0045099 biolink:CellularComponent obsolete vimentin OBSOLETE. A type of intermediate filament. go-plus.json vimentin http://purl.obolibrary.org/obo/GO_0045099 GO:0070059 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. go-plus.json ER stress-induced apoptosis|endoplasmic reticulum stress-induced apoptosis|apoptosis triggered by ER stress|apoptosis in response to ER stress|apoptosis in response to endoplasmic reticulum stress|intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_0070059 GO:0070057 biolink:CellularComponent prospore membrane spindle pole body attachment site The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus. go-plus.json forespore membrane spindle pole body attachment site|forespore membrane SPB attachment site|prospore membrane SPB attachment site http://purl.obolibrary.org/obo/GO_0070057 GO:0070058 biolink:BiologicalProcess tRNA gene clustering The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0070058 GO:0070055 biolink:BiologicalProcess obsolete mRNA endonucleolytic cleavage involved in unfolded protein response OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response. go-plus.json XBP1 mRNA cleavage|HAC1 mRNA cleavage|ERN1-mediated XBP-1 mRNA cleavage|IRE1-mediated XBP-1 mRNA cleavage|HAC1-type intron splice site recognition and cleavage http://purl.obolibrary.org/obo/GO_0070055 GO:0070056 biolink:CellularComponent prospore membrane leading edge The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization. go-plus.json forespore membrane leading edge http://purl.obolibrary.org/obo/GO_0070056 GO:0070042 biolink:MolecularActivity rRNA (uridine-N3-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine. go-plus.json http://purl.obolibrary.org/obo/GO_0070042 GO:0070043 biolink:MolecularActivity rRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine. Reactome:R-HSA-6790982 go-plus.json http://purl.obolibrary.org/obo/GO_0070043 GO:0070040 biolink:MolecularActivity rRNA (adenine-C2-)-methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA. MetaCyc:RXN-11586|EC:2.1.1.192 go-plus.json http://purl.obolibrary.org/obo/GO_0070040 GO:0070041 biolink:MolecularActivity rRNA (uridine-C5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine. go-plus.json http://purl.obolibrary.org/obo/GO_0070041 GO:0070048 biolink:CellularComponent endobrevin-SNAP-25-syntaxin-1a complex A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof). go-plus.json SNARE complex (Stx1a, Snap25, Vamp8)|Stx1a-Snap25-Vamp8 complex http://purl.obolibrary.org/obo/GO_0070048 GO:0070049 biolink:CellularComponent endobrevin-SNAP-25-syntaxin-2 complex A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof). go-plus.json Stx2-Snap25-Vamp8 complex|SNARE complex (Stx2, Snap25, Vamp8) http://purl.obolibrary.org/obo/GO_0070049 GO:0070046 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-3 complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof). go-plus.json SNARE complex (Stx3, Snap25, Vamp2)|Stx3-Snap25-Vamp2 complex http://purl.obolibrary.org/obo/GO_0070046 GO:0070047 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-4 complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof). go-plus.json SNARE complex (Stx4, Snap25, Vamp2)|Stx4-Snap25-Vamp2 complex http://purl.obolibrary.org/obo/GO_0070047 GO:0070044 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-1a complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof). go-plus.json Stx1a-SNAP25-VAMP complex|Snap25-Stx1a-Vamp2 complex|SNARE complex (Stx1a, SNAP25, VAMP)|SNARE complex (Snap25, Stx1a, Vamp2) http://purl.obolibrary.org/obo/GO_0070044 GO:0070045 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-2 complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof). go-plus.json SNARE complex (Stx2, Snap25, Vamp2)|Stx2-Snap25-Vamp2 complex http://purl.obolibrary.org/obo/GO_0070045 GO:0070075 biolink:BiologicalProcess tear secretion The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium. go-plus.json http://purl.obolibrary.org/obo/GO_0070075 GO:0070076 biolink:BiologicalProcess histone lysine demethylation The modification of a histone by the removal of a methyl group from a lysine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0070076 GO:0070073 biolink:BiologicalProcess clustering of voltage-gated calcium channels The process in which voltage-gated calcium channels become localized together in high densities. go-plus.json voltage-gated calcium channel clustering|clustering of voltage-dependent calcium channels|clustering of voltage gated calcium channels http://purl.obolibrary.org/obo/GO_0070073 GO:0070074 biolink:CellularComponent mononeme A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts. go-plus.json http://purl.obolibrary.org/obo/GO_0070074 GO:0070071 biolink:BiologicalProcess proton-transporting two-sector ATPase complex assembly The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0070071 GO:0070072 biolink:BiologicalProcess vacuolar proton-transporting V-type ATPase complex assembly The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane. go-plus.json V-ATPase assembly|V-ATPase complex assembly http://purl.obolibrary.org/obo/GO_0070072 UBERON:0037144 biolink:AnatomicalEntity wall of heart wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. go-plus.json cardiac wall http://purl.obolibrary.org/obo/UBERON_0037144 GO:0070070 biolink:BiologicalProcess proton-transporting V-type ATPase complex assembly The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. go-plus.json V-ATPase complex assembly|V-ATPase assembly http://purl.obolibrary.org/obo/GO_0070070 GO:0070079 biolink:BiologicalProcess histone H4-R3 demethylation The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0070079 GO:0070077 biolink:BiologicalProcess histone arginine demethylation The modification of a histone by the removal of a methyl group from an arginine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0070077 GO:0070078 biolink:BiologicalProcess histone H3-R2 demethylation The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0070078 GO:0070064 biolink:MolecularActivity proline-rich region binding Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070064 GO:0070065 biolink:CellularComponent cellubrevin-VAMP4-syntaxin-16 complex A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof). go-plus.json SNARE complex (Vamp3, Vamp4, Stx16)|Vamp3-Vamp4-Stx16 complex http://purl.obolibrary.org/obo/GO_0070065 GO:0070062 biolink:CellularComponent extracellular exosome A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. go-plus.json exosome|extracellular vesicular exosome http://purl.obolibrary.org/obo/GO_0070062 GO:0070063 biolink:MolecularActivity RNA polymerase binding Binding to an RNA polymerase molecule or complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070063 GO:0070060 biolink:BiologicalProcess 'de novo' actin filament nucleation The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament. go-plus.json formin-mediated actin filament nucleation|unbranched actin filament nucleation http://purl.obolibrary.org/obo/GO_0070060 GO:0070061 biolink:MolecularActivity fructose binding Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose. go-plus.json http://purl.obolibrary.org/obo/GO_0070061 GO:0035694 biolink:BiologicalProcess mitochondrial protein catabolic process The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. go-plus.json catabolism of mitochondrial protein|degradation of damaged mitochondrial protein http://purl.obolibrary.org/obo/GO_0035694 GO:0035695 biolink:BiologicalProcess mitophagy by induced vacuole formation The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes. go-plus.json MIV-mediated mitophagy http://purl.obolibrary.org/obo/GO_0035695 GO:0035696 biolink:BiologicalProcess monocyte extravasation The migration of a monocyte from the blood vessels into the surrounding tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0035696 GO:0035697 biolink:BiologicalProcess CD8-positive, alpha-beta T cell extravasation The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0035697 GO:0035698 biolink:BiologicalProcess CD8-positive, alpha-beta cytotoxic T cell extravasation The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0035698 GO:0035699 biolink:BiologicalProcess T-helper 17 cell extravasation The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0035699 GO:0070068 biolink:CellularComponent VAMP4-syntaxin-6-syntaxin-16-Vti1a complex A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof). go-plus.json Vamp4-Stx6-Stx16-Vti1a complex|SNARE complex (Vamp4, Stx6, Stx16, Vti1a) http://purl.obolibrary.org/obo/GO_0070068 GO:0035690 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035690 GO:0070069 biolink:CellularComponent cytochrome complex A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. go-plus.json http://purl.obolibrary.org/obo/GO_0070069 GO:0035691 biolink:BiologicalProcess macrophage migration inhibitory factor signaling pathway A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json macrophage migration inhibitory factor signalling pathway|MIF signaling pathway http://purl.obolibrary.org/obo/GO_0035691 GO:0035692 biolink:CellularComponent macrophage migration inhibitory factor receptor complex A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0035692 GO:0070066 biolink:CellularComponent cellubrevin-VAMP4-endobrevin-syntaxin-6 complex A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof). go-plus.json Vamp3-Vamp4-Vam8-Stx6 complex|SNARE complex (Vamp3, Vamp4, Vam8, Stx6) http://purl.obolibrary.org/obo/GO_0070066 GO:0035693 biolink:CellularComponent NOS2-CD74 complex A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases. go-plus.json http://purl.obolibrary.org/obo/GO_0035693 GO:0070067 biolink:CellularComponent syntaxin-6-syntaxin-16-Vti1a complex A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof). go-plus.json http://purl.obolibrary.org/obo/GO_0070067 GO:0070097 biolink:MolecularActivity delta-catenin binding Binding to the delta subunit of the catenin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070097 GO:0070098 biolink:BiologicalProcess chemokine-mediated signaling pathway A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json chemokine-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070098 GO:0070095 biolink:MolecularActivity fructose-6-phosphate binding Binding to fructose 6-phosphate. go-plus.json D-fructose 6-phosphate binding|fructose 6-phosphate binding http://purl.obolibrary.org/obo/GO_0070095 GO:0070096 biolink:BiologicalProcess mitochondrial outer membrane translocase complex assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex. go-plus.json TOM complex assembly|mitochondrion outer membrane translocase complex assembly http://purl.obolibrary.org/obo/GO_0070096 GO:0070093 biolink:BiologicalProcess negative regulation of glucagon secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. go-plus.json down-regulation of glucagon secretion|downregulation of glucagon secretion|down regulation of glucagon secretion|inhibition of glucagon secretion http://purl.obolibrary.org/obo/GO_0070093 GO:0070094 biolink:BiologicalProcess positive regulation of glucagon secretion Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. go-plus.json up regulation of glucagon secretion|upregulation of glucagon secretion|stimulation of glucagon secretion|activation of glucagon secretion|up-regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070094 GO:0070091 biolink:BiologicalProcess glucagon secretion The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). go-plus.json http://purl.obolibrary.org/obo/GO_0070091 GO:0070092 biolink:BiologicalProcess regulation of glucagon secretion Any process that modulates the frequency, rate or extent of the regulated release of glucagon. go-plus.json http://purl.obolibrary.org/obo/GO_0070092 GO:0070090 biolink:CellularComponent metaphase plate The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division. go-plus.json http://purl.obolibrary.org/obo/GO_0070090 GO:0035683 biolink:BiologicalProcess memory T cell extravasation The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive. go-plus.json memory T-cell extravasation http://purl.obolibrary.org/obo/GO_0035683 GO:0035684 biolink:BiologicalProcess helper T cell extravasation The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells. go-plus.json helper T-cell extravasation|T-helper cell extravasation http://purl.obolibrary.org/obo/GO_0035684 GO:0035685 biolink:BiologicalProcess helper T cell diapedesis The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. go-plus.json T-helper cell diapedesis|helper T-cell diapedesis http://purl.obolibrary.org/obo/GO_0035685 GO:0035686 biolink:CellularComponent sperm fibrous sheath A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat. go-plus.json flagellum fibrous sheath|flagellar fibrous sheath http://purl.obolibrary.org/obo/GO_0035686 GO:0035687 biolink:BiologicalProcess T-helper 1 cell extravasation The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. go-plus.json Th1 cell extravasation http://purl.obolibrary.org/obo/GO_0035687 GO:0035688 biolink:BiologicalProcess T-helper 1 cell diapedesis The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. go-plus.json Th1 cell diapedesis http://purl.obolibrary.org/obo/GO_0035688 GO:0035689 biolink:BiologicalProcess chemokine (C-C motif) ligand 5 signaling pathway A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL5-mediated signaling pathway|chemokine (C-C motif) ligand 5 signalling pathway|RANTES-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0035689 CHEBI:131698 biolink:ChemicalSubstance pregnane sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_131698 NCBITaxon:33317 biolink:OrganismalEntity Protostomia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33317 CHEBI:131699 biolink:ChemicalSubstance EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_131699 GO:0035680 biolink:BiologicalProcess posterior lateral line neuromast hair cell morphogenesis The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. go-plus.json http://purl.obolibrary.org/obo/GO_0035680 GO:0070099 biolink:BiologicalProcess regulation of chemokine-mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor. go-plus.json regulation of chemokine-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070099 GO:0035681 biolink:BiologicalProcess toll-like receptor 15 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 15. go-plus.json toll-like receptor 15 signalling pathway|TLR15 signaling pathway http://purl.obolibrary.org/obo/GO_0035681 GO:0035682 biolink:BiologicalProcess toll-like receptor 21 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 21. go-plus.json TLR21 signaling pathway|toll-like receptor 21 signalling pathway http://purl.obolibrary.org/obo/GO_0035682 GO:0070086 biolink:BiologicalProcess ubiquitin-dependent endocytosis Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded. go-plus.json ubiquitin-mediated endocytosis http://purl.obolibrary.org/obo/GO_0070086 GO:0070087 biolink:MolecularActivity chromo shadow domain binding Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain. go-plus.json chromoshadow domain binding http://purl.obolibrary.org/obo/GO_0070087 GO:0070084 biolink:BiologicalProcess protein initiator methionine removal The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein. go-plus.json removal of initiator methionine from protein http://purl.obolibrary.org/obo/GO_0070084 GO:0070085 biolink:BiologicalProcess glycosylation The covalent attachment and further modification of carbohydrate residues to a substrate molecule. Wikipedia:Glycosylation go-plus.json http://purl.obolibrary.org/obo/GO_0070085 GO:0070082 biolink:CellularComponent clathrin-sculpted monoamine transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle. go-plus.json clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen|clathrin sculpted monoamine transport vesicle lumen http://purl.obolibrary.org/obo/GO_0070082 GO:0070083 biolink:CellularComponent clathrin-sculpted monoamine transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle. go-plus.json clathrin sculpted monoamine transport vesicle membrane|clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane http://purl.obolibrary.org/obo/GO_0070083 GO:0070080 biolink:MolecularActivity titin Z domain binding Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. go-plus.json Z repeat domain binding http://purl.obolibrary.org/obo/GO_0070080 GO:0070081 biolink:CellularComponent clathrin-sculpted monoamine transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines. go-plus.json clathrin sculpted monoamine constitutive secretory pathway transport vesicle|clathrin sculpted monoamine transport vesicle http://purl.obolibrary.org/obo/GO_0070081 CHEBI:141013 biolink:ChemicalSubstance cob(II)inamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_141013 chebi_ph7_3 GO:0104004 biolink:BiologicalProcess cellular response to environmental stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0104004 GO:0104005 biolink:MolecularActivity obsolete hijacked molecular function OBSOLETE. A function that was not selected for in the evolution of an organism, but arises from co-option by another organism, e.g. a human protein used as a virus receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0104005 CHEBI:141014 biolink:ChemicalSubstance a pyrimidine ribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_141014 chebi_ph7_3 CHEBI:405237 biolink:ChemicalSubstance L-canavanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_405237 GO:0035672 biolink:BiologicalProcess oligopeptide transmembrane transport The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. go-plus.json oligopeptide membrane transport http://purl.obolibrary.org/obo/GO_0035672 GO:0035673 biolink:MolecularActivity oligopeptide transmembrane transporter activity Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. go-plus.json oligopeptide transporter activity http://purl.obolibrary.org/obo/GO_0035673 GO:0035674 biolink:BiologicalProcess tricarboxylic acid transmembrane transport The process in which a tricarboxylic acid is transported across a membrane. go-plus.json tricarboxylic acid membrane transport http://purl.obolibrary.org/obo/GO_0035674 GO:0035675 biolink:BiologicalProcess neuromast hair cell development The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0035675 GO:0035676 biolink:BiologicalProcess anterior lateral line neuromast hair cell development The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0035676 GO:0035677 biolink:BiologicalProcess posterior lateral line neuromast hair cell development The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0035677 GO:0035678 biolink:BiologicalProcess neuromast hair cell morphogenesis The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. go-plus.json http://purl.obolibrary.org/obo/GO_0035678 GO:0035679 biolink:BiologicalProcess anterior lateral line neuromast hair cell morphogenesis The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. go-plus.json http://purl.obolibrary.org/obo/GO_0035679 GO:0070088 biolink:CellularComponent PHA granule An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR. go-plus.json polyhydroxyalkanoate granule|PHB granule http://purl.obolibrary.org/obo/GO_0070088 GO:0035670 biolink:BiologicalProcess plant-type ovary development The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed. go-plus.json http://purl.obolibrary.org/obo/GO_0035670 GO:0035671 biolink:MolecularActivity enone reductase activity Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+. MetaCyc:RXN-12267 go-plus.json http://purl.obolibrary.org/obo/GO_0035671 GO:0070089 biolink:MolecularActivity chloride-activated potassium channel activity Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0070089 GO:1901729 biolink:BiologicalProcess monensin A catabolic process The chemical reactions and pathways resulting in the breakdown of monensin A. go-plus.json monensin catabolism|monensin degradation|monensin A catabolism|monensin A degradation|monensin breakdown|monensin A breakdown http://purl.obolibrary.org/obo/GO_1901729 GO:1901727 biolink:BiologicalProcess positive regulation of histone deacetylase activity Any process that activates or increases the frequency, rate or extent of histone deacetylase activity. go-plus.json up regulation of histone deacetylase activity|upregulation of histone deacetylase activity|activation of histone deacetylase activity|up-regulation of histone deacetylase activity http://purl.obolibrary.org/obo/GO_1901727 GO:1901728 biolink:BiologicalProcess monensin A metabolic process The chemical reactions and pathways involving monensin A. go-plus.json monensin metabolism|monensin A metabolism http://purl.obolibrary.org/obo/GO_1901728 GO:1901725 biolink:BiologicalProcess regulation of histone deacetylase activity Any process that modulates the frequency, rate or extent of histone deacetylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1901725 GO:1901726 biolink:BiologicalProcess negative regulation of histone deacetylase activity Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity. go-plus.json down-regulation of histone deacetylase activity|downregulation of histone deacetylase activity|down regulation of histone deacetylase activity|inhibition of histone deacetylase activity http://purl.obolibrary.org/obo/GO_1901726 GO:1901723 biolink:BiologicalProcess negative regulation of cell proliferation involved in kidney development Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. go-plus.json down regulation of cell proliferation involved in kidney development|downregulation of cell proliferation involved in kidney development|down-regulation of cell proliferation involved in kidney development|inhibition of cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_1901723 GO:1901724 biolink:BiologicalProcess positive regulation of cell proliferation involved in kidney development Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. go-plus.json up regulation of cell proliferation involved in kidney development|activation of cell proliferation involved in kidney development|up-regulation of cell proliferation involved in kidney development|upregulation of cell proliferation involved in kidney development http://purl.obolibrary.org/obo/GO_1901724 CHEBI:85480 biolink:ChemicalSubstance O-butenoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85480 chebi_ph7_3 GO:1901721 biolink:BiologicalProcess positive regulation of NMS complex assembly Any process that activates or increases the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation. go-plus.json up regulation of KMN complex interaction involved in chromosome segregation|upregulation of NMS complex association involved in chromosome segregation|upregulation of KMN network assembly involved in chromosome segregation|up regulation of NMS complex interaction involved in chromosome segregation|upregulation of KMN complex interaction involved in chromosome segregation|up-regulation of NMS complex association involved in chromosome segregation|positive regulation of NMS complex assembly involved in kinetochore assembly|up regulation of KMN network assembly involved in chromosome segregation|positive regulation of KMN network assembly involved in chromosome segregation|activation of NMS complex association involved in chromosome segregation|upregulation of NMS complex interaction involved in chromosome segregation|up-regulation of KMN complex interaction involved in chromosome segregation|activation of KMN complex assembly involved in chromosome segregation|positive regulation of NMS complex association involved in chromosome segregation|activation of KMN network assembly involved in chromosome segregation|up regulation of NMS complex association involved in chromosome segregation|up-regulation of KMN network assembly involved in chromosome segregation|up-regulation of NMS complex interaction involved in chromosome segregation|activation of NMS complex interaction involved in chromosome segregation|positive regulation of KMN complex interaction involved in chromosome segregation http://purl.obolibrary.org/obo/GO_1901721 UBERON:0013136 biolink:AnatomicalEntity vein of lip A vein that drains a lip. go-plus.json vena labialis|labial vein|lip vein|labial vein of face http://purl.obolibrary.org/obo/UBERON_0013136 CHEBI:85481 biolink:ChemicalSubstance 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85481 chebi_ph7_3 CHEBI:36508 biolink:ChemicalSubstance glycotriaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36508 GO:1901722 biolink:BiologicalProcess regulation of cell proliferation involved in kidney development Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development. go-plus.json http://purl.obolibrary.org/obo/GO_1901722 CHEBI:85482 biolink:ChemicalSubstance 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85482 chebi_ph7_3 CHEBI:85483 biolink:ChemicalSubstance 4-hydroxy-6-(2-methyldecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85483 chebi_ph7_3 GO:1901720 biolink:BiologicalProcess negative regulation of NMS complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation. go-plus.json inhibition of KMN network assembly involved in chromosome segregation|down-regulation of NMS complex interaction involved in chromosome segregation|downregulation of KMN complex interaction involved in chromosome segregation|inhibition of NMS complex association involved in chromosome segregation|down regulation of KMN complex assembly involved in chromosome segregation|down regulation of KMN network assembly involved in chromosome segregation|downregulation of NMS complex interaction involved in chromosome segregation|downregulation of KMN network assembly involved in chromosome segregation|inhibition of KMN complex interaction involved in chromosome segregation|down regulation of NMS complex interaction involved in chromosome segregation|negative regulation of NMS complex assembly involved in kinetochore assembly|inhibition of NMS complex interaction involved in chromosome segregation|negative regulation of NMS complex association involved in chromosome segregation|down-regulation of NMS complex association involved in chromosome segregation|down-regulation of KMN network assembly involved in chromosome segregation|negative regulation of KMN network assembly involved in chromosome segregation|down-regulation of KMN complex interaction involved in chromosome segregation|negative regulation of KMN complex interaction involved in chromosome segregation|downregulation of NMS complex association involved in chromosome segregation|down regulation of NMS complex association involved in chromosome segregation http://purl.obolibrary.org/obo/GO_1901720 UBERON:0013139 biolink:AnatomicalEntity ligament of liver A nonskeletal ligament that is part of a liver. go-plus.json liver ligament|hepatic ligament http://purl.obolibrary.org/obo/UBERON_0013139 CHEBI:36507 biolink:ChemicalSubstance D-galactosyl-N-acetyl-D-glucosaminyl-D-galactosyl-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36507 CHEBI:85484 biolink:ChemicalSubstance 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85484 chebi_ph7_3 CHEBI:85485 biolink:ChemicalSubstance 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85485 chebi_ph7_3 CHEBI:85488 biolink:ChemicalSubstance chloroeremomycin(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85488 chebi_ph7_3 CHEBI:85489 biolink:ChemicalSubstance cis-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85489 chebi_ph7_3 CHEBI:36500 biolink:ChemicalSubstance glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36500 chebi_ph7_3 CHEBI:36501 biolink:ChemicalSubstance (2Z,4Z)-5-carboxypenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36501 GO:0060630 biolink:BiologicalProcess obsolete regulation of M/G1 transition of mitotic cell cycle OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle. go-plus.json regulation of M/G1 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0060630 GO:0060631 biolink:BiologicalProcess regulation of meiosis I Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060631 GO:0060632 biolink:BiologicalProcess regulation of microtubule-based movement Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0060632 CHEBI:36504 biolink:ChemicalSubstance 5-carboxypenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36504 GO:0060633 biolink:BiologicalProcess negative regulation of transcription initiation from RNA polymerase II promoter Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0060633 CHEBI:36505 biolink:ChemicalSubstance labdane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36505 chebi_ph7_3 GO:0060634 biolink:BiologicalProcess regulation of 4,6-pyruvylated galactose residue biosynthetic process Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain. go-plus.json http://purl.obolibrary.org/obo/GO_0060634 GO:0060635 biolink:BiologicalProcess positive regulation of (1->3)-beta-D-glucan biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. go-plus.json positive regulation of 1,3-beta-D-glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0060635 CHEBI:12532 biolink:ChemicalSubstance N,N-dihydroxy-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_12532 CHEBI:36503 biolink:ChemicalSubstance menthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36503 chebi_ph7_3 GO:0060636 biolink:BiologicalProcess negative regulation of (1->3)-beta-D-glucan biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. go-plus.json negative regulation of 1,3-beta-D-glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0060636 GO:0060637 biolink:BiologicalProcess positive regulation of lactation by mesenchymal-epithelial cell signaling The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell. go-plus.json positive regulation of lactation by mesenchymal-epithelial cell signalling http://purl.obolibrary.org/obo/GO_0060637 GO:0060638 biolink:BiologicalProcess mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted. go-plus.json mesenchymal-epithelial cell signalling http://purl.obolibrary.org/obo/GO_0060638 GO:0060639 biolink:BiologicalProcess positive regulation of salivary gland formation by mesenchymal-epithelial signaling Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell. go-plus.json positive regulation of salivary gland formation by mesenchymal-epithelial signalling http://purl.obolibrary.org/obo/GO_0060639 GO:1901738 biolink:BiologicalProcess regulation of vitamin A metabolic process Any process that modulates the frequency, rate or extent of vitamin A metabolic process. go-plus.json regulation of vitamin A metabolism http://purl.obolibrary.org/obo/GO_1901738 GO:1901739 biolink:BiologicalProcess regulation of myoblast fusion Any process that modulates the frequency, rate or extent of myoblast fusion. go-plus.json http://purl.obolibrary.org/obo/GO_1901739 GO:1901736 biolink:BiologicalProcess (R)-mevalonic acid catabolic process The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid. go-plus.json (R)-mevalonic acid breakdown|(R)-mevalonic acid catabolism|(R)-mevalonate degradation|(R)-mevalonate breakdown|(R)-mevalonate catabolism|(R)-mevalonic acid degradation http://purl.obolibrary.org/obo/GO_1901736 GO:1901737 biolink:BiologicalProcess (R)-mevalonic acid biosynthetic process The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid. go-plus.json (R)-mevalonic acid biosynthesis|(R)-mevalonic acid anabolism|(R)-mevalonic acid synthesis|(R)-mevalonic acid formation|(R)-mevalonate biosynthesis|(R)-mevalonate anabolism|(R)-mevalonate synthesis http://purl.obolibrary.org/obo/GO_1901737 GO:1901734 biolink:BiologicalProcess quercetin biosynthetic process The chemical reactions and pathways resulting in the formation of quercetin. go-plus.json quercetin biosynthesis|quercetin anabolism|quercetin synthesis|quercetin formation http://purl.obolibrary.org/obo/GO_1901734 GO:1901735 biolink:BiologicalProcess (R)-mevalonic acid metabolic process The chemical reactions and pathways involving (R)-mevalonic acid. go-plus.json (R)-mevalonic acid metabolism|(R) mevalonate metabolism http://purl.obolibrary.org/obo/GO_1901735 PR:000022358 biolink:Protein adenylate cyclase A protein that is a translation product of the Escherichia coli K-12 cyaA gene or a 1:1 ortholog thereof. go-plus.json cyaA|ATP pyrophosphate-lyase|cya|adenylyl cyclase http://purl.obolibrary.org/obo/PR_000022358 GO:1901732 biolink:BiologicalProcess quercetin metabolic process The chemical reactions and pathways involving quercetin. go-plus.json quercetin metabolism http://purl.obolibrary.org/obo/GO_1901732 GO:0045006 biolink:BiologicalProcess DNA deamination The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil. go-plus.json http://purl.obolibrary.org/obo/GO_0045006 CHEBI:85471 biolink:ChemicalSubstance cobalt(II)-factor IV(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85471 chebi_ph7_3 GO:1901733 biolink:BiologicalProcess quercetin catabolic process The chemical reactions and pathways resulting in the breakdown of quercetin. go-plus.json quercetin catabolism|quercetin breakdown|quercetin degradation http://purl.obolibrary.org/obo/GO_1901733 UBERON:0013126 biolink:AnatomicalEntity vein of abdomen A vein that is part of a abdomen. go-plus.json abdominal vein http://purl.obolibrary.org/obo/UBERON_0013126 GO:0045007 biolink:BiologicalProcess depurination The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar. Wikipedia:Depurination go-plus.json http://purl.obolibrary.org/obo/GO_0045007 CHEBI:85472 biolink:ChemicalSubstance O-hydroxybutyryl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85472 chebi_ph7_3 GO:1901730 biolink:BiologicalProcess monensin A biosynthetic process The chemical reactions and pathways resulting in the formation of monensin A. go-plus.json monensin A biosynthesis|monensin anabolism|monensin A anabolism|monensin synthesis|monensin A synthesis|monensin formation|monensin A formation|monensin biosynthesis http://purl.obolibrary.org/obo/GO_1901730 CHEBI:36517 biolink:ChemicalSubstance germacrene A go-plus.json http://purl.obolibrary.org/obo/CHEBI_36517 chebi_ph7_3 GO:0045004 biolink:BiologicalProcess DNA replication proofreading Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_0045004 GO:0045005 biolink:BiologicalProcess DNA-dependent DNA replication maintenance of fidelity A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair. go-plus.json maintenance of fidelity involved in DNA-dependent DNA replication|maintenance of fidelity during DNA-dependent DNA replication http://purl.obolibrary.org/obo/GO_0045005 GO:1901731 biolink:BiologicalProcess positive regulation of platelet aggregation Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. go-plus.json up-regulation of thrombocyte aggregation|positive regulation of blood platelet aggregation|up regulation of blood platelet aggregation|up regulation of platelet aggregation|upregulation of thrombocyte aggregation|upregulation of blood platelet aggregation|up regulation of thrombocyte aggregation|upregulation of platelet aggregation|positive regulation of thrombocyte aggregation|up-regulation of blood platelet aggregation|activation of blood platelet aggregation|activation of thrombocyte aggregation|up-regulation of platelet aggregation|activation of platelet aggregation http://purl.obolibrary.org/obo/GO_1901731 CHEBI:85474 biolink:ChemicalSubstance 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85474 chebi_ph7_3 UBERON:0013121 biolink:AnatomicalEntity proximal epiphysis of phalanx of pes go-plus.json basal epiphysis of phalanx of foot|basis phalangis pedis|basis phalangis (pedis)|proximal epiphysis of phalanx of toe|base of phalanx of foot http://purl.obolibrary.org/obo/UBERON_0013121 GO:0045002 biolink:BiologicalProcess double-strand break repair via single-strand annealing Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats. go-plus.json http://purl.obolibrary.org/obo/GO_0045002 CHEBI:85475 biolink:ChemicalSubstance 4-hydroxy-6-(11-hydroxyheptadecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85475 chebi_ph7_3 UBERON:0013122 biolink:AnatomicalEntity distal epiphysis of phalanx of pes go-plus.json head of phalanx of foot|ungual tuberosity of distal phalanx of toe|distal epiphysis of phalanx of toe|caput phalangis pedis|distal end of phalanx of foot|caput phalangis (pedis) http://purl.obolibrary.org/obo/UBERON_0013122 GO:0045003 biolink:BiologicalProcess double-strand break repair via synthesis-dependent strand annealing SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. go-plus.json SDSA|mitotic gene conversion http://purl.obolibrary.org/obo/GO_0045003 CHEBI:85477 biolink:ChemicalSubstance 4-hydroxy-6-(15-hydroxypentadecyl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85477 chebi_ph7_3 GO:0045001 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045001 CHEBI:85479 biolink:ChemicalSubstance 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85479 chebi_ph7_3 GO:0060620 biolink:BiologicalProcess regulation of cholesterol import Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0060620 CHEBI:36515 biolink:ChemicalSubstance (-)-germacrene A go-plus.json http://purl.obolibrary.org/obo/CHEBI_36515 chebi_ph7_3 UBERON:0013118 biolink:AnatomicalEntity sulcus of brain A depression or fissure in the surface of the brain. It surrounds the gyri, creating the characteristic appearance of the brain in humans and other large mammals. go-plus.json fissure of brain|sulcus|sulci & spaces|cerebral sulcus|cerebral sulci|cerebral sulci http://purl.obolibrary.org/obo/UBERON_0013118 GO:0060621 biolink:BiologicalProcess negative regulation of cholesterol import Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0060621 GO:0060622 biolink:BiologicalProcess regulation of ascospore wall beta-glucan biosynthetic process Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. go-plus.json http://purl.obolibrary.org/obo/GO_0060622 CHEBI:36513 biolink:ChemicalSubstance cadinane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36513 chebi_ph7_3 GO:0045008 biolink:BiologicalProcess depyrimidination The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar. go-plus.json http://purl.obolibrary.org/obo/GO_0045008 GO:0060623 biolink:BiologicalProcess regulation of chromosome condensation Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060623 CHEBI:36514 biolink:ChemicalSubstance germacrane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36514 chebi_ph7_3 GO:0060624 biolink:BiologicalProcess regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores. go-plus.json regulation of ascospore wall 1,3-beta-glucan biosynthetic process|regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0060624 GO:0045009 biolink:CellularComponent chitosome An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum. go-plus.json http://purl.obolibrary.org/obo/GO_0045009 GO:0060625 biolink:BiologicalProcess regulation of protein deneddylation Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein. go-plus.json regulation of cullin deneddylation http://purl.obolibrary.org/obo/GO_0060625 GO:0060626 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060626 GO:0060627 biolink:BiologicalProcess regulation of vesicle-mediated transport Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060627 GO:0060628 biolink:BiologicalProcess regulation of ER to Golgi vesicle-mediated transport Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi. go-plus.json http://purl.obolibrary.org/obo/GO_0060628 GO:0060629 biolink:BiologicalProcess regulation of homologous chromosome segregation Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets. go-plus.json http://purl.obolibrary.org/obo/GO_0060629 GO:0045010 biolink:BiologicalProcess actin nucleation The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament. go-plus.json actin filament nucleation http://purl.obolibrary.org/obo/GO_0045010 GO:1901749 biolink:BiologicalProcess leukotriene D4 catabolic process The chemical reactions and pathways resulting in the breakdown of leukotriene D4. go-plus.json leukotriene D4 catabolism|leukotriene D4 degradation|leukotriene D4 breakdown http://purl.obolibrary.org/obo/GO_1901749 GO:1901747 biolink:BiologicalProcess prephenate(2-) biosynthetic process The chemical reactions and pathways resulting in the formation of prephenate(2-). go-plus.json prephenate(2-) biosynthesis|prephenate(2-) anabolism|prephenate anabolism|prephenate(2-) synthesis|prephenate(2-) formation|prephenate synthesis|prephenate formation|prephenate biosynthesis http://purl.obolibrary.org/obo/GO_1901747 GO:1901748 biolink:BiologicalProcess leukotriene D4 metabolic process The chemical reactions and pathways involving leukotriene D4. go-plus.json leukotriene D4 metabolism http://purl.obolibrary.org/obo/GO_1901748 GO:1901745 biolink:BiologicalProcess prephenate(2-) metabolic process The chemical reactions and pathways involving prephenate(2-). go-plus.json prephenate(2-) metabolism|prephenate metabolism http://purl.obolibrary.org/obo/GO_1901745 GO:1901746 biolink:BiologicalProcess prephenate(2-) catabolic process The chemical reactions and pathways resulting in the breakdown of prephenate(2-). go-plus.json prephenate degradation|prephenate(2-) breakdown|prephenate breakdown|prephenate catabolism|prephenate(2-) catabolism|prephenate(2-) degradation http://purl.obolibrary.org/obo/GO_1901746 GO:0045017 biolink:BiologicalProcess glycerolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone. go-plus.json glycerolipid anabolism|glycerolipid biosynthesis|glycerolipid synthesis|glycerolipid formation http://purl.obolibrary.org/obo/GO_0045017 GO:1901743 biolink:BiologicalProcess 2-deoxystreptamine catabolic process The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine. go-plus.json 2-deoxystreptamine degradation|2-deoxystreptamine breakdown|2-deoxystreptamine catabolism http://purl.obolibrary.org/obo/GO_1901743 GO:1901744 biolink:BiologicalProcess 2-deoxystreptamine biosynthetic process The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine. go-plus.json 2-deoxystreptamine formation|2-deoxystreptamine biosynthesis|2-deoxystreptamine anabolism|2-deoxystreptamine synthesis http://purl.obolibrary.org/obo/GO_1901744 GO:0045018 biolink:BiologicalProcess retrograde transport, vacuole to Golgi The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment. go-plus.json retrograde transport from the vacuole http://purl.obolibrary.org/obo/GO_0045018 GO:0045015 biolink:MolecularActivity HDEL sequence binding Binding to a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum. go-plus.json HDEL receptor activity http://purl.obolibrary.org/obo/GO_0045015 GO:1901741 biolink:BiologicalProcess positive regulation of myoblast fusion Any process that activates or increases the frequency, rate or extent of myoblast fusion. go-plus.json up regulation of myoblast fusion|activation of myoblast fusion|up-regulation of myoblast fusion|upregulation of myoblast fusion http://purl.obolibrary.org/obo/GO_1901741 GO:1901742 biolink:BiologicalProcess 2-deoxystreptamine metabolic process The chemical reactions and pathways involving 2-deoxystreptamine. go-plus.json 2-deoxystreptamine metabolism http://purl.obolibrary.org/obo/GO_1901742 GO:0045016 biolink:BiologicalProcess mitochondrial magnesium ion transmembrane transport The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json mitochondrial magnesium ion transport http://purl.obolibrary.org/obo/GO_0045016 GO:0045013 biolink:BiologicalProcess carbon catabolite repression of transcription A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. go-plus.json negative regulation of transcription by carbon catabolites|carbon catabolite repression http://purl.obolibrary.org/obo/GO_0045013 GO:1901740 biolink:BiologicalProcess negative regulation of myoblast fusion Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion. go-plus.json down-regulation of myoblast fusion|inhibition of myoblast fusion|down regulation of myoblast fusion|downregulation of myoblast fusion http://purl.obolibrary.org/obo/GO_1901740 GO:0045014 biolink:BiologicalProcess carbon catabolite repression of transcription by glucose A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. go-plus.json down-regulation of transcription by glucose|glucose repression|downregulation of transcription by glucose|down regulation of transcription by glucose|glucose effect|inhibition of transcription by glucose http://purl.obolibrary.org/obo/GO_0045014 GO:0045011 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045011 GO:0045012 biolink:MolecularActivity obsolete MHC class II receptor activity OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes. go-plus.json MHC class II receptor activity|major histocompatibility complex class II receptor|class II major histocompatibility complex antigen http://purl.obolibrary.org/obo/GO_0045012 GO:0060650 biolink:BiologicalProcess epithelial cell proliferation involved in mammary gland bud elongation The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060650 GO:0060651 biolink:BiologicalProcess regulation of epithelial cell proliferation involved in mammary gland bud elongation Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060651 GO:0060652 biolink:BiologicalProcess mammary gland cord morphogenesis The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat. go-plus.json mammary gland sprout morphogenesis http://purl.obolibrary.org/obo/GO_0060652 GO:0060653 biolink:BiologicalProcess epithelial cell differentiation involved in mammary gland cord morphogenesis The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified. go-plus.json epithelial cell differentiation involved in mammary gland sprout morphogenesis http://purl.obolibrary.org/obo/GO_0060653 GO:0060654 biolink:BiologicalProcess mammary gland cord elongation The process in which the mammary gland sprout grows along its axis. go-plus.json http://purl.obolibrary.org/obo/GO_0060654 GO:0060655 biolink:BiologicalProcess branching involved in mammary gland cord morphogenesis The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct. go-plus.json http://purl.obolibrary.org/obo/GO_0060655 GO:0060656 biolink:BiologicalProcess regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell. go-plus.json regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling http://purl.obolibrary.org/obo/GO_0060656 GO:0045019 biolink:BiologicalProcess negative regulation of nitric oxide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. go-plus.json negative regulation of nitric oxide biosynthesis|down-regulation of nitric oxide biosynthetic process|inhibition of nitric oxide biosynthetic process|negative regulation of nitric oxide anabolism|down regulation of nitric oxide biosynthetic process|negative regulation of nitric oxide synthesis|negative regulation of nitric oxide formation|downregulation of nitric oxide biosynthetic process http://purl.obolibrary.org/obo/GO_0045019 GO:0060657 biolink:BiologicalProcess regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell. go-plus.json regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling http://purl.obolibrary.org/obo/GO_0060657 GO:0060658 biolink:BiologicalProcess nipple morphogenesis The process in which the nipple is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060658 GO:0060659 biolink:BiologicalProcess nipple sheath formation The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate. go-plus.json http://purl.obolibrary.org/obo/GO_0060659 GO:0045020 biolink:BiologicalProcess obsolete error-prone DNA repair OBSOLETE. DNA repair pathways that tend to increase the endogenous mutation rate. go-plus.json mutagenic DNA repair|error-prone DNA repair http://purl.obolibrary.org/obo/GO_0045020 NCBITaxon:33340 biolink:OrganismalEntity Neoptera go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33340 GO:0045021 biolink:BiologicalProcess obsolete error-free DNA repair OBSOLETE. DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways. go-plus.json error-free DNA repair http://purl.obolibrary.org/obo/GO_0045021 GO:1901758 biolink:BiologicalProcess butirosin biosynthetic process The chemical reactions and pathways resulting in the formation of butirosin. go-plus.json butirosin synthesis|butirosin formation|butirosin biosynthesis|butirosin anabolism http://purl.obolibrary.org/obo/GO_1901758 GO:1901759 biolink:BiologicalProcess beta-L-Ara4N-lipid A metabolic process The chemical reactions and pathways involving beta-L-Ara4N-lipid A. go-plus.json 4-amino-4-deoxy-beta-L-arabinose-lipid A metabolic process|beta-L-Ara4N-lipid A metabolism|4-amino-4-deoxy-beta-L-arabinose-lipid A metabolism http://purl.obolibrary.org/obo/GO_1901759 GO:1901756 biolink:BiologicalProcess butirosin metabolic process The chemical reactions and pathways involving butirosin. go-plus.json butirosin metabolism http://purl.obolibrary.org/obo/GO_1901756 CHEBI:85490 biolink:ChemicalSubstance 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85490 chebi_ph7_3 CHEBI:85491 biolink:ChemicalSubstance epivancomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85491 chebi_ph7_3 GO:1901757 biolink:BiologicalProcess butirosin catabolic process The chemical reactions and pathways resulting in the breakdown of butirosin. go-plus.json butirosin catabolism|butirosin degradation|butirosin breakdown http://purl.obolibrary.org/obo/GO_1901757 GO:1901754 biolink:BiologicalProcess vitamin D3 catabolic process The chemical reactions and pathways resulting in the breakdown of vitamin D3. go-plus.json vitamin D3 degradation|vitamin D3 breakdown|calciol catabolism|cholecalciferol catabolic process|calciol degradation|vitamin D3 catabolism|calciol breakdown|cholecalciferol catabolism|calciol catabolic process http://purl.obolibrary.org/obo/GO_1901754 GO:0045028 biolink:MolecularActivity G protein-coupled purinergic nucleotide receptor activity Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein coupled purinergic nucleotide receptor activity|P2Y receptor|purinergic nucleotide receptor activity, G-protein coupled|purinergic nucleotide receptor activity, G protein coupled|P2Y|G protein coupled purinergic nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0045028 CHEBI:85492 biolink:ChemicalSubstance 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85492 chebi_ph7_3 GO:1901755 biolink:BiologicalProcess vitamin D3 biosynthetic process The chemical reactions and pathways resulting in the formation of vitamin D3. go-plus.json calciol synthesis|calciol formation|calciol biosynthesis|calciol biosynthetic process|vitamin D3 anabolism|vitamin D3 synthesis|vitamin D3 biosynthesis|vitamin D3 formation|cholecalciferol biosynthesis|cholecalciferol biosynthetic process|calciol anabolism http://purl.obolibrary.org/obo/GO_1901755 GO:0045029 biolink:MolecularActivity G protein-coupled UDP receptor activity Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP. go-plus.json UDP-activated nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0045029 CHEBI:85493 biolink:ChemicalSubstance 4-saturated-trans-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85493 chebi_ph7_3 GO:1901752 biolink:BiologicalProcess leukotriene A4 catabolic process The chemical reactions and pathways resulting in the breakdown of leukotriene A4. go-plus.json leukotriene A4 breakdown|leukotriene A4 catabolism|leukotriene A4 degradation http://purl.obolibrary.org/obo/GO_1901752 GO:0045026 biolink:BiologicalProcess plasma membrane fusion The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. go-plus.json cell fusion|cell-cell fusion http://purl.obolibrary.org/obo/GO_0045026 CHEBI:85494 biolink:ChemicalSubstance 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85494 chebi_ph7_3 CHEBI:85495 biolink:ChemicalSubstance 4-hydroxy-6-(16-hydroxy-2-oxohexadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85495 chebi_ph7_3 GO:0045027 biolink:MolecularActivity DNA end binding Binding to DNA ends exposed by the creation of double-strand breaks (DSBs). go-plus.json http://purl.obolibrary.org/obo/GO_0045027 GO:1901753 biolink:BiologicalProcess leukotriene A4 biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene A4. go-plus.json LTA4 biosynthesis|eoxin A4 biosynthesis|leukotriene A4 anabolism|leukotriene A4 synthesis|leukotriene A4 formation|leukotriene A4 biosynthesis http://purl.obolibrary.org/obo/GO_1901753 GO:0045024 biolink:MolecularActivity obsolete peptidyl-glutamyl peptide hydrolyzing enzyme activity OBSOLETE. Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids. go-plus.json peptidyl-glutamyl peptide hydrolyzing enzyme activity http://purl.obolibrary.org/obo/GO_0045024 CHEBI:85496 biolink:ChemicalSubstance 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85496 chebi_ph7_3 GO:1901750 biolink:BiologicalProcess leukotriene D4 biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene D4. go-plus.json leukotriene D4 anabolism|leukotriene D4 synthesis|leukotriene D4 formation|leukotriene D4 biosynthesis http://purl.obolibrary.org/obo/GO_1901750 GO:0045025 biolink:CellularComponent mitochondrial degradosome A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer. go-plus.json mtEXO http://purl.obolibrary.org/obo/GO_0045025 GO:1901751 biolink:BiologicalProcess leukotriene A4 metabolic process The chemical reactions and pathways involving leukotriene A4. go-plus.json leukotriene A4 metabolism http://purl.obolibrary.org/obo/GO_1901751 CHEBI:85497 biolink:ChemicalSubstance 4-hydroxy-6-(4-methyl-2-oxododecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85497 chebi_ph7_3 GO:0045022 biolink:BiologicalProcess early endosome to late endosome transport The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs. go-plus.json http://purl.obolibrary.org/obo/GO_0045022 CHEBI:85498 biolink:ChemicalSubstance 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85498 chebi_ph7_3 GO:0045023 biolink:BiologicalProcess G0 to G1 transition The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression. go-plus.json http://purl.obolibrary.org/obo/GO_0045023 CHEBI:85499 biolink:ChemicalSubstance 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85499 chebi_ph7_3 GO:0060640 biolink:BiologicalProcess positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud. go-plus.json positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling|positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling http://purl.obolibrary.org/obo/GO_0060640 GO:0060641 biolink:BiologicalProcess mammary gland duct regression in males The process in which the epithelium of the mammary duct is destroyed in males. go-plus.json http://purl.obolibrary.org/obo/GO_0060641 GO:0060642 biolink:BiologicalProcess white fat cell differentiation involved in mammary gland fat development The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0060642 GO:0060643 biolink:BiologicalProcess epithelial cell differentiation involved in mammary gland bud morphogenesis The process in which a cell of the mammary placode becomes a cell of the mammary gland bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060643 GO:0060644 biolink:BiologicalProcess mammary gland epithelial cell differentiation The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060644 GO:0060645 biolink:BiologicalProcess peripheral mammary gland bud epithelial cell differentiation The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically. go-plus.json http://purl.obolibrary.org/obo/GO_0060645 GO:0060646 biolink:BiologicalProcess internal mammary gland bud epithelial cell differentiation The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape. go-plus.json http://purl.obolibrary.org/obo/GO_0060646 GO:0060647 biolink:BiologicalProcess mesenchymal cell condensation involved in mammary fat development The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development. go-plus.json http://purl.obolibrary.org/obo/GO_0060647 GO:0060648 biolink:BiologicalProcess mammary gland bud morphogenesis The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord. go-plus.json http://purl.obolibrary.org/obo/GO_0060648 GO:0060649 biolink:BiologicalProcess mammary gland bud elongation The process in which the mammary gland bud grows along its axis. go-plus.json http://purl.obolibrary.org/obo/GO_0060649 GO:0045031 biolink:MolecularActivity G protein-coupled ATP receptor activity Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json ATP-activated adenosine receptor activity|ATP-activated nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0045031 GO:0045032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045032 GO:0045030 biolink:MolecularActivity G protein-coupled UTP receptor activity Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP. go-plus.json uridine nucleotide receptor activity|UTP-activated nucleotide receptor activity|purinoceptor type U http://purl.obolibrary.org/obo/GO_0045030 GO:1901769 biolink:BiologicalProcess carbapenem biosynthetic process The chemical reactions and pathways resulting in the formation of carbapenem. go-plus.json carbapenem anabolism|carbapenem synthesis|carbapenem formation|carbapenem biosynthesis http://purl.obolibrary.org/obo/GO_1901769 GO:1901767 biolink:BiologicalProcess carbapenem metabolic process The chemical reactions and pathways involving carbapenem. go-plus.json carbapenem metabolism http://purl.obolibrary.org/obo/GO_1901767 GO:1901768 biolink:BiologicalProcess carbapenem catabolic process The chemical reactions and pathways resulting in the breakdown of carbapenem. go-plus.json carbapenem degradation|carbapenem breakdown|carbapenem catabolism http://purl.obolibrary.org/obo/GO_1901768 GO:1901765 biolink:BiologicalProcess phosphinothricin catabolic process The chemical reactions and pathways resulting in the breakdown of phosphinothricin. go-plus.json phosphinothricin degradation|phosphinothricin catabolism|phosphinothricin breakdown http://purl.obolibrary.org/obo/GO_1901765 GO:0045039 biolink:BiologicalProcess protein insertion into mitochondrial inner membrane The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane. go-plus.json protein import into mitochondrial inner membrane|mitochondrial inner membrane protein import|protein transport into mitochondrial inner membrane http://purl.obolibrary.org/obo/GO_0045039 GO:1901766 biolink:BiologicalProcess phosphinothricin biosynthetic process The chemical reactions and pathways resulting in the formation of phosphinothricin. go-plus.json phosphinothricin biosynthesis|phosphinothricin anabolism|phosphinothricin synthesis|phosphinothricin formation http://purl.obolibrary.org/obo/GO_1901766 GO:1901763 biolink:BiologicalProcess oxytetracycline biosynthetic process The chemical reactions and pathways resulting in the formation of oxytetracycline. go-plus.json oxytetracycline synthesis|oxytetracycline formation|oxytetracycline biosynthesis|oxytetracycline anabolism http://purl.obolibrary.org/obo/GO_1901763 GO:0045037 biolink:BiologicalProcess protein import into chloroplast stroma The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import. go-plus.json chloroplast stroma protein import|protein transport into chloroplast stroma http://purl.obolibrary.org/obo/GO_0045037 GO:0045038 biolink:BiologicalProcess protein import into chloroplast thylakoid membrane The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma. go-plus.json chloroplast thylakoid membrane protein import|protein transport into chloroplast thylakoid membrane http://purl.obolibrary.org/obo/GO_0045038 GO:1901764 biolink:BiologicalProcess phosphinothricin metabolic process The chemical reactions and pathways involving phosphinothricin. go-plus.json phosphinothricin metabolism http://purl.obolibrary.org/obo/GO_1901764 GO:1901761 biolink:BiologicalProcess oxytetracycline metabolic process The chemical reactions and pathways involving oxytetracycline. go-plus.json oxytetracycline metabolism http://purl.obolibrary.org/obo/GO_1901761 GO:0045035 biolink:BiologicalProcess sensory organ precursor cell division The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron). go-plus.json sense organ precursor cell division http://purl.obolibrary.org/obo/GO_0045035 GO:1901762 biolink:BiologicalProcess oxytetracycline catabolic process The chemical reactions and pathways resulting in the breakdown of oxytetracycline. go-plus.json oxytetracycline catabolism|oxytetracycline degradation|oxytetracycline breakdown http://purl.obolibrary.org/obo/GO_1901762 GO:0045036 biolink:BiologicalProcess protein targeting to chloroplast The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved. go-plus.json protein-chloroplast targeting http://purl.obolibrary.org/obo/GO_0045036 GO:0060670 biolink:BiologicalProcess branching involved in labyrinthine layer morphogenesis The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. go-plus.json http://purl.obolibrary.org/obo/GO_0060670 GO:0045033 biolink:BiologicalProcess peroxisome inheritance The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p. go-plus.json http://purl.obolibrary.org/obo/GO_0045033 GO:1901760 biolink:BiologicalProcess beta-L-Ara4N-lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system. go-plus.json 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis|4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthetic process|beta-L-Ara4N-lipid A anabolism|beta-L-Ara4N-lipid A synthesis|beta-L-Ara4N-lipid A formation|beta-L-Ara4N-lipid A biosynthesis http://purl.obolibrary.org/obo/GO_1901760 GO:0045034 biolink:BiologicalProcess obsolete neuroblast division OBSOLETE. The asymmetrical division of a neuroblast, the neural precursor in the central nervous system, giving rise to another neuroblast and a ganglion mother cell. go-plus.json neuroblast division (sensu Nematoda and Protostomia)|neuroblast division|neuroblast cell division|neuroblast division (sensu Vertebrata) http://purl.obolibrary.org/obo/GO_0045034 GO:0060671 biolink:BiologicalProcess epithelial cell differentiation involved in embryonic placenta development The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer. go-plus.json http://purl.obolibrary.org/obo/GO_0060671 GO:0060672 biolink:BiologicalProcess epithelial cell morphogenesis involved in placental branching The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0060672 GO:0060673 biolink:BiologicalProcess cell-cell signaling involved in placenta development Any process that mediates the transfer of information from one cell to another. go-plus.json cell-cell signalling involved in placenta development http://purl.obolibrary.org/obo/GO_0060673 GO:0060674 biolink:BiologicalProcess placenta blood vessel development The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060674 GO:0060675 biolink:BiologicalProcess ureteric bud morphogenesis The process in which the ureteric bud is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060675 GO:0060676 biolink:BiologicalProcess ureteric bud formation The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060676 GO:0060677 biolink:BiologicalProcess ureteric bud elongation The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated. go-plus.json http://purl.obolibrary.org/obo/GO_0060677 GO:0060678 biolink:BiologicalProcess dichotomous subdivision of terminal units involved in ureteric bud branching The process in which a ureteric bud bifurcates at its end. go-plus.json bifid subdivision of terminal units involved in ureteric bud branching http://purl.obolibrary.org/obo/GO_0060678 GO:0060679 biolink:BiologicalProcess trifid subdivision of terminal units involved in ureteric bud branching The process in which a ureteric bud splits into three units at its end. go-plus.json http://purl.obolibrary.org/obo/GO_0060679 UBERON:0013161 biolink:AnatomicalEntity left lateral ventricle A telencephalic ventricle that is in_the_left_side_of a telencephalon. go-plus.json left telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0013161 GO:0045042 biolink:BiologicalProcess obsolete protein import into mitochondrial intermembrane space, conservative OBSOLETE. The conservative import of proteins into the mitochondrial intermembrane space. The entire protein enters the matrix, and then the second targeting sequence directs the protein, presumably bound to a matrix protein, across the inner membrane to the intermembrane space. go-plus.json conservative protein transport into mitochondrial IMS|protein import into mitochondrial intermembrane space, conservative|conservative mitochondrial IMS protein import|protein import into mitochondrial IMS, conservative|protein transport into mitochondrial intermembrane space, conservative|conservative mitochondrial intermembrane space protein import|protein transport into mitochondrial IMS, conservative|conservative protein transport into mitochondrial intermembrane space http://purl.obolibrary.org/obo/GO_0045042 UBERON:0013162 biolink:AnatomicalEntity right lateral ventricle A telencephalic ventricle that is in_the_right_side_of a telencephalon. go-plus.json right telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0013162 GO:0045043 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045043 GO:0045040 biolink:BiologicalProcess protein insertion into mitochondrial outer membrane The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes. go-plus.json protein transport into mitochondrial outer membrane|mitochondrial outer membrane protein import|protein import into mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0045040 GO:0045041 biolink:BiologicalProcess protein import into mitochondrial intermembrane space The import of proteins into the space between the inner and outer mitochondrial membranes. go-plus.json mitochondrial intermembrane space protein import|protein import into mitochondrial IMS|protein transport into mitochondrial intermembrane space|protein import into mitochondrial intermembrane space, nonconservative|protein transport into mitochondrial IMS|protein import into mitochondrial intermembrane space, direct http://purl.obolibrary.org/obo/GO_0045041 GO:1901778 biolink:BiologicalProcess pentalenolactone metabolic process The chemical reactions and pathways involving pentalenolactone. go-plus.json pentalenolactone metabolism http://purl.obolibrary.org/obo/GO_1901778 UBERON:0013160 biolink:AnatomicalEntity epithalamus ventricular layer go-plus.json ventricular layer epithalamus|ventricular layer of epithalamus http://purl.obolibrary.org/obo/UBERON_0013160 GO:1901779 biolink:BiologicalProcess pentalenolactone catabolic process The chemical reactions and pathways resulting in the breakdown of pentalenolactone. go-plus.json pentalenolactone breakdown|pentalenolactone catabolism|pentalenolactone degradation http://purl.obolibrary.org/obo/GO_1901779 GO:1901776 biolink:BiologicalProcess mitomycin C catabolic process The chemical reactions and pathways resulting in the breakdown of mitomycin C. go-plus.json mitomycin C degradation|mitomycin C breakdown|mitomycin C catabolism http://purl.obolibrary.org/obo/GO_1901776 GO:1901777 biolink:BiologicalProcess mitomycin C biosynthetic process The chemical reactions and pathways resulting in the formation of mitomycin C. go-plus.json mitomycin C biosynthesis|mitomycin C anabolism|mitomycin C synthesis|mitomycin C formation http://purl.obolibrary.org/obo/GO_1901777 GO:0045048 biolink:BiologicalProcess protein insertion into ER membrane The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. go-plus.json protein-ER insertion|integral ER membrane protein localization|protein insertion into endoplasmic reticulum membrane|protein-endoplasmic reticulum insertion|integral ER membrane protein positioning|positioning of protein in ER membrane|localization of protein in ER membrane http://purl.obolibrary.org/obo/GO_0045048 GO:1901774 biolink:BiologicalProcess lincomycin biosynthetic process The chemical reactions and pathways resulting in the formation of lincomycin. go-plus.json lincomycin anabolism|lincomycin synthesis|lincomycin formation|lincomycin biosynthesis http://purl.obolibrary.org/obo/GO_1901774 GO:1901775 biolink:BiologicalProcess mitomycin C metabolic process The chemical reactions and pathways involving mitomycin C. go-plus.json mitomycin C metabolism http://purl.obolibrary.org/obo/GO_1901775 GO:0045049 biolink:BiologicalProcess protein insertion into ER membrane by N-terminal cleaved signal sequence A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER. go-plus.json protein insertion into endoplasmic reticulum membrane by N-terminal cleaved signal sequence|protein insertion into ER membrane, N-terminal cleaved signal sequence mediated|protein-endoplasmic reticulum insertion by N-terminal cleaved signal sequence|protein-ER insertion by N-terminal cleaved signal sequence|N-terminal cleaved signal sequence mediated protein insertion into ER membrane http://purl.obolibrary.org/obo/GO_0045049 GO:1901772 biolink:BiologicalProcess lincomycin metabolic process The chemical reactions and pathways involving lincomycin. go-plus.json lincomycin metabolism http://purl.obolibrary.org/obo/GO_1901772 GO:0045046 biolink:BiologicalProcess protein import into peroxisome membrane The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import. go-plus.json protein transport into peroxisome membrane|peroxisome membrane protein import http://purl.obolibrary.org/obo/GO_0045046 GO:1901773 biolink:BiologicalProcess lincomycin catabolic process The chemical reactions and pathways resulting in the breakdown of lincomycin. go-plus.json lincomycin breakdown|lincomycin catabolism|lincomycin degradation http://purl.obolibrary.org/obo/GO_1901773 GO:0045047 biolink:BiologicalProcess protein targeting to ER The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. go-plus.json protein-endoplasmic reticulum targeting|protein targeting to endoplasmic reticulum|protein-ER targeting http://purl.obolibrary.org/obo/GO_0045047 GO:1901770 biolink:BiologicalProcess daunorubicin catabolic process The chemical reactions and pathways resulting in the breakdown of daunorubicin. go-plus.json daunorubicin degradation|daunorubicin catabolism|daunorubicin breakdown http://purl.obolibrary.org/obo/GO_1901770 GO:0045044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045044 GO:1901771 biolink:BiologicalProcess daunorubicin biosynthetic process The chemical reactions and pathways resulting in the formation of daunorubicin. go-plus.json daunorubicin anabolism|daunorubicin synthesis|daunorubicin formation|daunorubicin biosynthesis http://purl.obolibrary.org/obo/GO_1901771 GO:0045045 biolink:BiologicalProcess obsolete secretory pathway OBSOLETE. The pathway along which proteins and other substances are moved around and out of the cell. After synthesis on the ribosomes of the endoplasmic reticulum (ER), completed polypeptide chains are moved to the Golgi complex and subsequently sorted to various destinations. Proteins synthesized and sorted in the secretory pathway include not only those that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes as well as integral proteins in the membranes of these organelles and the plasma membrane. go-plus.json secretory pathway http://purl.obolibrary.org/obo/GO_0045045 GO:0060660 biolink:BiologicalProcess epidermis morphogenesis involved in nipple formation The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection. go-plus.json http://purl.obolibrary.org/obo/GO_0060660 GO:0060661 biolink:BiologicalProcess submandibular salivary gland formation The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed. go-plus.json http://purl.obolibrary.org/obo/GO_0060661 GO:1901780 biolink:BiologicalProcess pentalenolactone biosynthetic process The chemical reactions and pathways resulting in the formation of pentalenolactone. go-plus.json pentalenolactone biosynthesis|pentalenolactone anabolism|pentalenolactone synthesis|pentalenolactone formation http://purl.obolibrary.org/obo/GO_1901780 GO:0060662 biolink:BiologicalProcess salivary gland cavitation The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland. go-plus.json salivary gland invagination http://purl.obolibrary.org/obo/GO_0060662 GO:0060663 biolink:BiologicalProcess apoptotic process involved in salivary gland cavitation Any apoptotic process in which the solid core of the gland is hollowed out to form the duct. go-plus.json apoptosis involved in salivary gland cavitation http://purl.obolibrary.org/obo/GO_0060663 GO:0060664 biolink:BiologicalProcess epithelial cell proliferation involved in salivary gland morphogenesis The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060664 GO:0060665 biolink:BiologicalProcess regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium. go-plus.json regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalling http://purl.obolibrary.org/obo/GO_0060665 GO:0060666 biolink:BiologicalProcess dichotomous subdivision of terminal units involved in salivary gland branching The process in which a salivary epithelial cord bifurcates at its end. go-plus.json http://purl.obolibrary.org/obo/GO_0060666 GO:0060667 biolink:BiologicalProcess branch elongation involved in salivary gland morphogenesis The differential growth of the salivary branches along their axis, resulting in the growth of a branch. go-plus.json http://purl.obolibrary.org/obo/GO_0060667 GO:0060668 biolink:BiologicalProcess regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland. go-plus.json regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalling http://purl.obolibrary.org/obo/GO_0060668 GO:0060669 biolink:BiologicalProcess embryonic placenta morphogenesis The process in which the embryonic placenta is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060669 GO:0045053 biolink:BiologicalProcess protein retention in Golgi apparatus The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known. go-plus.json retention of protein in Golgi|maintenance of protein location in Golgi apparatus|protein-Golgi retention http://purl.obolibrary.org/obo/GO_0045053 UBERON:0013150 biolink:AnatomicalEntity future brain vesicle go-plus.json brain vesicle|secondary brain vesicle|primary brain vesicle|primitive brain vesicle|early brain vesicle http://purl.obolibrary.org/obo/UBERON_0013150 GO:0070010 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070010 GO:0045054 biolink:BiologicalProcess constitutive secretory pathway A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space. go-plus.json constitutive exocytosis http://purl.obolibrary.org/obo/GO_0045054 UBERON:0013151 biolink:AnatomicalEntity choroidal artery One of two arteries (anterior and posterior choroidal artery) that supply blood to the choroid plexus, optic tract, hippocampus, globus pallidus, and other various brain regions. go-plus.json choroid artery|artery of choroid plexus http://purl.obolibrary.org/obo/UBERON_0013151 GO:0045051 biolink:BiologicalProcess protein insertion into ER membrane by internal uncleaved signal-anchor sequence A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences. go-plus.json protein insertion into ER membrane, internal uncleaved signal-anchor sequence mediated|protein-ER insertion by internal uncleaved signal-anchor sequence|internal uncleaved signal-anchor sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by internal uncleaved signal-anchor sequence|protein insertion into endoplasmic reticulum membrane by internal uncleaved signal-anchor sequence http://purl.obolibrary.org/obo/GO_0045051 GO:0045052 biolink:BiologicalProcess protein insertion into ER membrane by GPI attachment sequence A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule. go-plus.json protein-ER insertion by GPI attachment sequence|GPI attachment sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by GPI attachment sequence|protein insertion into endoplasmic reticulum membrane by GPI attachment sequence|protein insertion into ER membrane, GPI attachment sequence mediated http://purl.obolibrary.org/obo/GO_0045052 GO:0045050 biolink:BiologicalProcess protein insertion into ER membrane by stop-transfer membrane-anchor sequence A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix. go-plus.json protein insertion into ER membrane, stop-transfer membrane-anchor sequence mediated|protein-ER insertion by stop-transfer membrane-anchor sequence|stop-transfer membrane-anchor sequence mediated protein insertion into ER membrane|protein insertion into endoplasmic reticulum membrane by stop-transfer membrane-anchor sequence|protein-endoplasmic reticulum insertion by stop-transfer membrane-anchor sequence http://purl.obolibrary.org/obo/GO_0045050 NCBITaxon:33392 biolink:OrganismalEntity Endopterygota go-plus.json Holometabola http://purl.obolibrary.org/obo/NCBITaxon_33392 GO:1901789 biolink:BiologicalProcess benzoyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of benzoyl-CoA. go-plus.json benzoyl-CoA anabolism|benzoyl-CoA biosynthesis|benzoyl-CoA synthesis|benzoyl-CoA formation http://purl.obolibrary.org/obo/GO_1901789 GO:1901787 biolink:BiologicalProcess benzoyl-CoA metabolic process The chemical reactions and pathways involving benzoyl-CoA. go-plus.json benzoyl-CoA metabolism http://purl.obolibrary.org/obo/GO_1901787 UBERON:0013158 biolink:AnatomicalEntity foregut-midgut junction gland A gland that is part of a foregut-midgut junction. go-plus.json gland of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0013158 UBERON:0013159 biolink:AnatomicalEntity epithalamus mantle layer go-plus.json mantle layer epithalamus|mantle layer of epithalamus http://purl.obolibrary.org/obo/UBERON_0013159 GO:1901788 biolink:BiologicalProcess benzoyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA. go-plus.json benzoyl-CoA degradation|benzoyl-CoA breakdown|benzoyl-CoA catabolism http://purl.obolibrary.org/obo/GO_1901788 GO:1901785 biolink:BiologicalProcess p-cresol catabolic process The chemical reactions and pathways resulting in the breakdown of p-cresol. go-plus.json p-cresol degradation|p-cresol catabolism|p-cresol breakdown http://purl.obolibrary.org/obo/GO_1901785 GO:0045059 biolink:BiologicalProcess positive thymic T cell selection The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death. go-plus.json positive thymic T lymphocyte selection|positive thymic T-cell selection|positive thymic T-lymphocyte selection http://purl.obolibrary.org/obo/GO_0045059 GO:1901786 biolink:BiologicalProcess p-cresol biosynthetic process The chemical reactions and pathways resulting in the formation of p-cresol. go-plus.json p-cresol anabolism|p-cresol synthesis|p-cresol formation|p-cresol biosynthesis http://purl.obolibrary.org/obo/GO_1901786 GO:0045057 biolink:BiologicalProcess cisternal progression The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna. go-plus.json cisternal maturation http://purl.obolibrary.org/obo/GO_0045057 GO:1901783 biolink:BiologicalProcess p-cumate biosynthetic process The chemical reactions and pathways resulting in the formation of p-cumate. go-plus.json p-cumate anabolism|p-cumate synthesis|p-cumate formation|p-cumate biosynthesis http://purl.obolibrary.org/obo/GO_1901783 GO:0060690 biolink:BiologicalProcess epithelial cell differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060690 GO:0045058 biolink:BiologicalProcess T cell selection The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. Wikipedia:Thymocyte go-plus.json T-cell selection|T-lymphocyte selection|T lymphocyte selection http://purl.obolibrary.org/obo/GO_0045058 GO:1901784 biolink:BiologicalProcess p-cresol metabolic process The chemical reactions and pathways involving p-cresol. go-plus.json p-cresol metabolism http://purl.obolibrary.org/obo/GO_1901784 GO:0060691 biolink:BiologicalProcess epithelial cell maturation involved in salivary gland development The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0060691 GO:1901781 biolink:BiologicalProcess p-cumate metabolic process The chemical reactions and pathways involving p-cumate. go-plus.json p-cumate metabolism http://purl.obolibrary.org/obo/GO_1901781 GO:0045055 biolink:BiologicalProcess regulated exocytosis A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. go-plus.json regulated secretory pathway http://purl.obolibrary.org/obo/GO_0045055 GO:0060692 biolink:BiologicalProcess mesenchymal cell differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. go-plus.json http://purl.obolibrary.org/obo/GO_0060692 UBERON:0013156 biolink:AnatomicalEntity 1st arch mandibular endoderm go-plus.json endoderm of mandibular component http://purl.obolibrary.org/obo/UBERON_0013156 GO:0045056 biolink:BiologicalProcess transcytosis The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Wikipedia:Transcytosis go-plus.json http://purl.obolibrary.org/obo/GO_0045056 GO:0060693 biolink:BiologicalProcess regulation of branching involved in salivary gland morphogenesis Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0060693 GO:1901782 biolink:BiologicalProcess p-cumate catabolic process The chemical reactions and pathways resulting in the breakdown of p-cumate. go-plus.json p-cumate catabolism|p-cumate degradation|p-cumate breakdown http://purl.obolibrary.org/obo/GO_1901782 GO:1901790 biolink:BiologicalProcess 3-(2,3-dihydroxyphenyl)propanoate metabolic process The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate. go-plus.json 3-(2,3-dihydroxyphenyl)propanoate metabolism http://purl.obolibrary.org/obo/GO_1901790 GO:0060694 biolink:BiologicalProcess regulation of cholesterol transporter activity Any process that modulates the rate, frequency, or extent of cholesterol transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_0060694 GO:1901791 biolink:BiologicalProcess 3-(2,3-dihydroxyphenyl)propanoate catabolic process The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate. go-plus.json 3-(2,3-dihydroxyphenyl)propanoate catabolism|3-(2,3-dihydroxyphenyl)propanoate degradation|3-(2,3-dihydroxyphenyl)propanoate breakdown http://purl.obolibrary.org/obo/GO_1901791 GO:0060695 biolink:BiologicalProcess negative regulation of cholesterol transporter activity Any process that decreases the rate, frequency, or extent of cholesterol transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_0060695 GO:0060696 biolink:BiologicalProcess regulation of phospholipid catabolic process Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. go-plus.json http://purl.obolibrary.org/obo/GO_0060696 GO:0060697 biolink:BiologicalProcess positive regulation of phospholipid catabolic process Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. go-plus.json http://purl.obolibrary.org/obo/GO_0060697 GO:0060698 biolink:MolecularActivity endoribonuclease inhibitor activity Binds to and stops, prevents or reduces the activity of endoribonuclease. go-plus.json http://purl.obolibrary.org/obo/GO_0060698 GO:0060699 biolink:BiologicalProcess regulation of endoribonuclease activity Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. go-plus.json http://purl.obolibrary.org/obo/GO_0060699 GO:0070019 biolink:CellularComponent obsolete transforming growth factor beta type II receptor homodimeric complex OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers. go-plus.json TGF-beta type II receptor complex|TGFBR2 homodimer|transforming growth factor beta type II receptor complex|TGF-beta type II receptor dimer http://purl.obolibrary.org/obo/GO_0070019 GO:0070017 biolink:CellularComponent alphav-beta3 integrin-thrombospondin complex A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin. go-plus.json ITGAV-ITGB3-THBS1 complex http://purl.obolibrary.org/obo/GO_0070017 GO:0070018 biolink:CellularComponent obsolete transforming growth factor beta type I receptor homodimeric complex OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers. go-plus.json TGFBR1 homodimer|TGF-beta type I receptor dimer|TGF-beta type I receptor complex|transforming growth factor beta type I receptor complex http://purl.obolibrary.org/obo/GO_0070018 GO:0070015 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070015 GO:0070016 biolink:MolecularActivity armadillo repeat domain binding Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation. go-plus.json armadillo repeat binding|Arm repeat domain binding|armadillo domain binding http://purl.obolibrary.org/obo/GO_0070016 GO:0070013 biolink:CellularComponent intracellular organelle lumen An organelle lumen that is part of an intracellular organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0070013 goslim_mouse GO:0070014 biolink:CellularComponent sucrase-isomaltase complex A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities. Wikipedia:Sucrase-isomaltase go-plus.json oligo-1,6-glucosidase complex http://purl.obolibrary.org/obo/GO_0070014 GO:0070011 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070011 GO:0070012 biolink:MolecularActivity oligopeptidase activity Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0070012 GO:0045064 biolink:BiologicalProcess T-helper 2 cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. go-plus.json T-helper 2 cell development http://purl.obolibrary.org/obo/GO_0045064 GO:0045065 biolink:BiologicalProcess cytotoxic T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell. go-plus.json cytotoxic T-lymphocyte selection|cytotoxic T lymphocyte selection|cytotoxic T cell development|cytotoxic T-cell selection http://purl.obolibrary.org/obo/GO_0045065 UBERON:0013140 biolink:AnatomicalEntity systemic vein Any vein within the general circulation that transports blood back to the right atrium of the heart. go-plus.json systemic venous tree organ part http://purl.obolibrary.org/obo/UBERON_0013140 GO:0045062 biolink:BiologicalProcess extrathymic T cell selection The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus. go-plus.json extrathymic T-cell selection|extrathymic T-lymphocyte selection|extrathymic T lymphocyte selection http://purl.obolibrary.org/obo/GO_0045062 GO:0045063 biolink:BiologicalProcess T-helper 1 cell differentiation The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. go-plus.json T-helper 1 cell development http://purl.obolibrary.org/obo/GO_0045063 GO:0045060 biolink:BiologicalProcess negative thymic T cell selection The process of elimination of immature T cells in the thymus which react strongly with self-antigens. go-plus.json negative thymic T-cell selection|negative thymic T-lymphocyte selection|negative thymic T lymphocyte selection http://purl.obolibrary.org/obo/GO_0045060 GO:0045061 biolink:BiologicalProcess thymic T cell selection The process of T cell selection that occurs in the thymus. go-plus.json thymic T lymphocyte selection|thymic T-cell selection|thymic T-lymphocyte selection http://purl.obolibrary.org/obo/GO_0045061 GO:1901798 biolink:BiologicalProcess positive regulation of signal transduction by p53 class mediator Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator. go-plus.json upregulation of signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator|up-regulation of signal transduction by p53 class mediator http://purl.obolibrary.org/obo/GO_1901798 GO:1901799 biolink:BiologicalProcess negative regulation of proteasomal protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process. go-plus.json downregulation of proteasome-mediated protein catabolism|inhibition of proteasome-mediated protein catabolic process|down-regulation of proteasomal protein catabolic process|down regulation of proteasome-mediated protein catabolism|inhibition of proteasomal protein catabolic process|down regulation of proteasome-mediated protein catabolic process|inhibition of proteasome-mediated protein catabolism|downregulation of proteasome-mediated protein catabolic process|down regulation of proteasomal protein catabolic process|down-regulation of proteasome-mediated protein catabolic process|negative regulation of proteasome-mediated protein catabolic process|down-regulation of proteasome-mediated protein catabolism|negative regulation of proteasome-mediated protein catabolism|downregulation of proteasomal protein catabolic process http://purl.obolibrary.org/obo/GO_1901799 GO:1901796 biolink:BiologicalProcess regulation of signal transduction by p53 class mediator Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. go-plus.json http://purl.obolibrary.org/obo/GO_1901796 UBERON:0013149 biolink:AnatomicalEntity hindbrain vesicle go-plus.json rhombencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0013149 GO:1901797 biolink:BiologicalProcess negative regulation of signal transduction by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator. go-plus.json down regulation of signal transduction by p53 class mediator|downregulation of signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator|inhibition of signal transduction by p53 class mediator http://purl.obolibrary.org/obo/GO_1901797 GO:1901794 biolink:BiologicalProcess 3-(3-hydroxyphenyl)propanoate catabolic process The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate. go-plus.json 3-(3-hydroxyphenyl)propanoate catabolism|3-(3-hydroxyphenyl)propanoate degradation|3-(3-hydroxyphenyl)propanoate breakdown http://purl.obolibrary.org/obo/GO_1901794 GO:0045068 biolink:BiologicalProcess negative extrathymic T cell selection The process of elimination of extrathymically maturing T cells which react strongly with self-antigens. go-plus.json negative extrathymic T-cell selection|negative extrathymic T-lymphocyte selection|negative extrathymic T lymphocyte selection http://purl.obolibrary.org/obo/GO_0045068 GO:1901795 biolink:BiologicalProcess 3-(3-hydroxyphenyl)propanoate biosynthetic process The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate. go-plus.json 3-(3-hydroxyphenyl)propanoate anabolism|3-(3-hydroxyphenyl)propanoate synthesis|3-(3-hydroxyphenyl)propanoate formation|3-(3-hydroxyphenyl)propanoate biosynthesis http://purl.obolibrary.org/obo/GO_1901795 GO:0060680 biolink:BiologicalProcess lateral sprouting involved in ureteric bud morphogenesis The process in which a branch forms along the side of a ureteric bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060680 GO:0045069 biolink:BiologicalProcess regulation of viral genome replication Any process that modulates the frequency, rate or extent of viral genome replication. go-plus.json http://purl.obolibrary.org/obo/GO_0045069 GO:1901792 biolink:BiologicalProcess 3-(2,3-dihydroxyphenyl)propanoate biosynthetic process The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate. go-plus.json 3-(2,3-dihydroxyphenyl)propanoate anabolism|3-(2,3-dihydroxyphenyl)propanoate synthesis|3-(2,3-dihydroxyphenyl)propanoate formation|3-(2,3-dihydroxyphenyl)propanoate biosynthesis http://purl.obolibrary.org/obo/GO_1901792 GO:0045066 biolink:BiologicalProcess regulatory T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types. go-plus.json regulatory T cell development|suppressor T cell differentiation|suppressor T lymphocyte differentiation|regulatory T lymphocyte differentiation|regulatory T-cell differentiation|suppressor T-cell differentiation|suppressor T-lymphocyte differentiation|regulatory T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045066 GO:0060681 biolink:BiologicalProcess branch elongation involved in ureteric bud branching The growth of a branch of the ureteric bud along its axis. go-plus.json http://purl.obolibrary.org/obo/GO_0060681 GO:1901793 biolink:BiologicalProcess 3-(3-hydroxyphenyl)propanoate metabolic process The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate. go-plus.json 3-(3-hydroxyphenyl)propanoate metabolism http://purl.obolibrary.org/obo/GO_1901793 GO:0060682 biolink:BiologicalProcess primary ureteric bud growth The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema. go-plus.json http://purl.obolibrary.org/obo/GO_0060682 GO:0045067 biolink:BiologicalProcess positive extrathymic T cell selection The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. go-plus.json positive extrathymic T-cell selection|positive extrathymic T cell selection|positive extrathymic T-lymphocyte selection|positive extrathymic T lymphocyte selection http://purl.obolibrary.org/obo/GO_0045067 GO:0060683 biolink:BiologicalProcess regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland. go-plus.json regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalling http://purl.obolibrary.org/obo/GO_0060683 GO:0060684 biolink:BiologicalProcess epithelial-mesenchymal cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. go-plus.json epithelial-mesenchymal cell signalling http://purl.obolibrary.org/obo/GO_0060684 GO:0060685 biolink:BiologicalProcess regulation of prostatic bud formation Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. go-plus.json http://purl.obolibrary.org/obo/GO_0060685 GO:0060686 biolink:BiologicalProcess negative regulation of prostatic bud formation Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. go-plus.json http://purl.obolibrary.org/obo/GO_0060686 GO:0060687 biolink:BiologicalProcess regulation of branching involved in prostate gland morphogenesis Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. go-plus.json http://purl.obolibrary.org/obo/GO_0060687 GO:0060688 biolink:BiologicalProcess regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060688 GO:0070008 biolink:MolecularActivity serine-type exopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). EC:3.4.21.- go-plus.json http://purl.obolibrary.org/obo/GO_0070008 GO:0060689 biolink:BiologicalProcess cell differentiation involved in salivary gland development The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060689 GO:0070009 biolink:MolecularActivity serine-type aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). go-plus.json http://purl.obolibrary.org/obo/GO_0070009 GO:0070006 biolink:MolecularActivity metalloaminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. go-plus.json http://purl.obolibrary.org/obo/GO_0070006 GO:0070007 biolink:MolecularActivity glutamic-type endopeptidase activity Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad. go-plus.json http://purl.obolibrary.org/obo/GO_0070007 GO:0070004 biolink:MolecularActivity cysteine-type exopeptidase activity Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. go-plus.json http://purl.obolibrary.org/obo/GO_0070004 GO:0070005 biolink:MolecularActivity cysteine-type aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. EC:3.4.18.- go-plus.json http://purl.obolibrary.org/obo/GO_0070005 GO:0070002 biolink:MolecularActivity glutamic-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad. go-plus.json http://purl.obolibrary.org/obo/GO_0070002 GO:0070003 biolink:MolecularActivity threonine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile. go-plus.json http://purl.obolibrary.org/obo/GO_0070003 GO:0070001 biolink:MolecularActivity aspartic-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. go-plus.json http://purl.obolibrary.org/obo/GO_0070001 UBERON:0003849 biolink:AnatomicalEntity mesencephalic neural crest A neural crest that has_potential_to_developmentally_contribute_to a midbrain. go-plus.json neural crest midbrain|mesencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003849 UBERON:0003847 biolink:AnatomicalEntity thyroid artery A artery that supplies a thyroid gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003847 UBERON:0003848 biolink:AnatomicalEntity gonadal vein In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]. go-plus.json vein of gonad|gonad vein|gonada vein|vein of gonada http://purl.obolibrary.org/obo/UBERON_0003848 UBERON:0003846 biolink:AnatomicalEntity thymus epithelium An epithelium that is part of a thymus, forming a supporting framework[MP,modified]. go-plus.json thymus gland epithelium|thymus epithelial tissue|thymic epithelial tissue|epithelial tissue of thymus gland|epithelium of thymus gland|thymic epithelium|thymus gland epithelial tissue|epithelial tissue of thymus|epithelium of thymus http://purl.obolibrary.org/obo/UBERON_0003846 GO:0035823 biolink:BiologicalProcess short tract gene conversion A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0035823 CHEBI:131711 biolink:ChemicalSubstance (S)-demethyl-4-deoxygadusol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131711 chebi_ph7_3 GO:0035824 biolink:BiologicalProcess long tract gene conversion A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0035824 GO:0035825 biolink:BiologicalProcess homologous recombination A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules. Wikipedia:Chromosomal_crossover go-plus.json chromosomal crossover|interstrand DNA recombination|reciprocal DNA recombination|interchromosomal DNA recombination http://purl.obolibrary.org/obo/GO_0035825 GO:0035826 biolink:BiologicalProcess obsolete rubidium ion transport OBSOLETE. The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json Rb+ transport|rubidium cation transport http://purl.obolibrary.org/obo/GO_0035826 CHEBI:61430 biolink:ChemicalSubstance decanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61430 chebi_ph7_3 GO:0035827 biolink:MolecularActivity obsolete rubidium ion transmembrane transporter activity OBSOLETE. Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other. go-plus.json Rb+ transmembrane transporter activity|rubidium transmembrane transporter activity|rubidium cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0035827 GO:0035828 biolink:BiologicalProcess obsolete renal rubidium ion transport OBSOLETE. The directed movement of rubidium ions (Rb+) by the kidney. go-plus.json renal Rb+ transport|renal rubidium cation transport http://purl.obolibrary.org/obo/GO_0035828 GO:0035829 biolink:BiologicalProcess obsolete renal rubidium ion absorption OBSOLETE. A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. go-plus.json renal Rb+ absorption|renal rubidium cation absorption http://purl.obolibrary.org/obo/GO_0035829 CHEBI:131717 biolink:ChemicalSubstance 2-epi-valiolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_131717 chebi_ph7_3 CHEBI:131718 biolink:ChemicalSubstance S-(1-hydroxy-2-methylbut-3-en-2-yl)glutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131718 chebi_ph7_3 CHEBI:85400 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85400 CHEBI:85401 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85401 CHEBI:36465 biolink:ChemicalSubstance cis-1,6-dihydroxycyclohexa-2,4-dienecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36465 CHEBI:85403 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85403 CHEBI:85404 biolink:ChemicalSubstance 3-dehydrocarnityl CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85404 chebi_ph7_3 CHEBI:85405 biolink:ChemicalSubstance N,N,N-trimethylglycyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85405 chebi_ph7_3 GO:0035820 biolink:BiologicalProcess negative regulation of renal sodium excretion by angiotensin The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time. go-plus.json http://purl.obolibrary.org/obo/GO_0035820 GO:0035821 biolink:BiologicalProcess modulation of process of other organism The process in which an organism effects a change in the structure or processes of another organism. go-plus.json regulation of physiological process of other organism|regulation of physiology of other organism|modification of morphology or physiology of other organism|regulation of morphology of other organism|regulation of morphology or physiology of other organism http://purl.obolibrary.org/obo/GO_0035821 CHEBI:85407 biolink:ChemicalSubstance 1-palmitoyl-sn-glycero-3-phosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85407 CHEBI:61437 biolink:ChemicalSubstance fructoselysine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61437 GO:0035822 biolink:BiologicalProcess gene conversion A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor. go-plus.json http://purl.obolibrary.org/obo/GO_0035822 CHEBI:85408 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85408 CHEBI:131710 biolink:ChemicalSubstance S-(1-hydroxy-2-oxopropyl)-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_131710 chebi_ph7_3 UBERON:0003854 biolink:AnatomicalEntity spinal cord neural plate A neural plate that develops_from a future spinal cord. go-plus.json neural plate of spinal cord http://purl.obolibrary.org/obo/UBERON_0003854 CHEBI:85409 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85409 UBERON:0003855 biolink:AnatomicalEntity gonad mesenchyme Mesenchyme that is part of a developing gonad [Automatically generated definition]. go-plus.json mesenchyme of gonad|gonada mesenchyme|mesenchyme of gonada http://purl.obolibrary.org/obo/UBERON_0003855 CHEBI:36460 biolink:ChemicalSubstance (E)-glutaconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36460 chebi_ph7_3 UBERON:0003852 biolink:AnatomicalEntity rhombencephalon neural crest A neural crest that has_potential_to_developmentally_contribute_to a hindbrain. go-plus.json neural crest hindbrain|rhombomere neural crest|rhombencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003852 UBERON:0003853 biolink:AnatomicalEntity spinal cord neural crest A neural crest that has_potential_to_developmentally_contribute_to a spinal cord. go-plus.json neural crest spinal cord|spinal neural crest http://purl.obolibrary.org/obo/UBERON_0003853 UBERON:0003850 biolink:AnatomicalEntity telencephalon neural crest A neural crest that has_potential_to_developmentally_contribute_to a telencephalon. go-plus.json neural crest telencephalon http://purl.obolibrary.org/obo/UBERON_0003850 UBERON:0003851 biolink:AnatomicalEntity diencephalon neural crest A neural crest that has_potential_to_developmentally_contribute_to a diencephalon. go-plus.json neural crest diencephalon|neural crest of future diencephalon|diencephalic neural crest|future diencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0003851 CHEBI:36464 biolink:ChemicalSubstance (R)-mevalonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36464 chebi_ph7_3 CHEBI:36461 biolink:ChemicalSubstance (E)-glutaconate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36461 CHEBI:36462 biolink:ChemicalSubstance glutaconate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36462 UBERON:0003838 biolink:AnatomicalEntity abdominal segment connective tissue A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]. go-plus.json abdominal segment of trunk portion of connective tissue|abdominal segment of trunk connective tissue|abdominal segment of trunk textus connectivus|portion of connective tissue of abdominal segment of trunk|textus connectivus of abdominal segment of trunk|connective tissue of abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0003838 UBERON:0003839 biolink:AnatomicalEntity forelimb joint A limb joint that is part of a forelimb [Automatically generated definition]. go-plus.json limb joint of superior member|anteriormost limb joint of limb|upper extremity joint of limb|joint of limb of forelimb|fore limb joint of limb|joint of limb of superior member|wing joint|forelimb joint of limb|limb joint of forelimb|superior member limb joint|limb joint of anteriormost limb|limb joint of upper extremity|limb joint of fore limb|joint of free upper limb|superior member joint of limb|forelimb limb joint|joint of limb of upper extremity|joint of limb of anteriormost limb|joint of limb of fore limb|fore limb limb joint|anteriormost limb limb joint|upper extremity limb joint http://purl.obolibrary.org/obo/UBERON_0003839 UBERON:0003836 biolink:AnatomicalEntity abdominal segment skin A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]. go-plus.json abdominal segment of trunk skin|skin of abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0003836 UBERON:0003837 biolink:AnatomicalEntity thoracic segment connective tissue A portion of connective tissue that is part of a thorax [Automatically generated definition]. go-plus.json portion of connective tissue of thorax|thorax portion of connective tissue|textus connectivus of thorax|thorax textus connectivus|upper body connective tissue|connective tissue of thorax|thorax connective tissue http://purl.obolibrary.org/obo/UBERON_0003837 UBERON:0003834 biolink:AnatomicalEntity thoracic segment blood vessel A blood vessel that is part of a thorax [Automatically generated definition]. go-plus.json upper body blood vessel|blood vessel of thorax|thorax blood vessel http://purl.obolibrary.org/obo/UBERON_0003834 UBERON:0003835 biolink:AnatomicalEntity abdominal segment blood vessel A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]. go-plus.json abdominal segment of trunk blood vessel|blood vessel of abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0003835 GO:0035812 biolink:BiologicalProcess renal sodium excretion The elimination by an organism of sodium in the urine. go-plus.json http://purl.obolibrary.org/obo/GO_0035812 GO:0035813 biolink:BiologicalProcess regulation of renal sodium excretion Any process that modulates the amount of sodium excreted in urine over a unit of time. go-plus.json http://purl.obolibrary.org/obo/GO_0035813 GO:0035814 biolink:BiologicalProcess negative regulation of renal sodium excretion Any process that decreases the amount of sodium excreted in urine over a unit of time. go-plus.json http://purl.obolibrary.org/obo/GO_0035814 CHEBI:131725 biolink:ChemicalSubstance coproporphyrin III(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131725 chebi_ph7_3 GO:0035815 biolink:BiologicalProcess positive regulation of renal sodium excretion Any process that increases the amount of sodium excreted in urine over a unit of time. go-plus.json natriuresis http://purl.obolibrary.org/obo/GO_0035815 GO:0035816 biolink:BiologicalProcess renal water absorption involved in negative regulation of urine volume Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time. go-plus.json http://purl.obolibrary.org/obo/GO_0035816 CHEBI:131727 biolink:ChemicalSubstance hydroxylipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131727 chebi_ph7_3 GO:0035817 biolink:BiologicalProcess renal sodium ion absorption involved in negative regulation of renal sodium excretion Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time. go-plus.json http://purl.obolibrary.org/obo/GO_0035817 CHEBI:61442 biolink:ChemicalSubstance tetrahydrofolyl-poly(glutamate) polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61442 GO:0035818 biolink:BiologicalProcess positive regulation of urine volume by pressure natriuresis An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis. go-plus.json diuresis resulting from pressure natriuresis http://purl.obolibrary.org/obo/GO_0035818 CHEBI:131728 biolink:ChemicalSubstance [Glu(-Cys)]n-Gly(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131728 chebi_ph7_3 GO:0035819 biolink:BiologicalProcess positive regulation of renal sodium excretion by pressure natriuresis An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis. go-plus.json natriuresis resulting from pressure natriuresis http://purl.obolibrary.org/obo/GO_0035819 CHEBI:61440 biolink:ChemicalSubstance UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61440 CHEBI:61445 biolink:ChemicalSubstance poly(amide) polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61445 CHEBI:36476 biolink:ChemicalSubstance 1-stearoylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36476 CHEBI:61444 biolink:ChemicalSubstance gamma-poly(glutamate) polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61444 CHEBI:36477 biolink:ChemicalSubstance sulfoglycosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36477 CHEBI:61449 biolink:ChemicalSubstance (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61449 chebi_ph7_3 CHEBI:131720 biolink:ChemicalSubstance (3R)-3,4-epoxy-3-methylbut-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_131720 chebi_ph7_3 GO:0035810 biolink:BiologicalProcess positive regulation of urine volume Any process that increases the amount of urine excreted from the body over a unit of time. go-plus.json increase in urine flow|elevation of urinary volume|diuresis http://purl.obolibrary.org/obo/GO_0035810 GO:0035811 biolink:BiologicalProcess negative regulation of urine volume Any process that decreases the amount of urine excreted from the body over a unit of time. go-plus.json decrease in urine flow|antidiuresis|reduction of urinary volume http://purl.obolibrary.org/obo/GO_0035811 UBERON:0003843 biolink:AnatomicalEntity dental epithelium Epithelium that is part of a developing tooth or dental organ. go-plus.json odontogenic epithelium|reduced enamel epithelium|dental epithelia|tooth epithelium|dental epithelium http://purl.obolibrary.org/obo/UBERON_0003843 CHEBI:36470 biolink:ChemicalSubstance quinazoline alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36470 UBERON:0003841 biolink:AnatomicalEntity autopod joint A limb joint that is part of an autopod [Automatically generated definition]. go-plus.json distal free limb segment joint of limb|limb joint of distal free limb segment|paw joint|joint of limb of autopod|autopod limb joint|autopod joint of limb|joint of limb of distal free limb segment|distal free limb segment limb joint|limb joint of autopod http://purl.obolibrary.org/obo/UBERON_0003841 UBERON:0003842 biolink:AnatomicalEntity neural tube lumen An anatomical space that surrounded_by a neural tube. go-plus.json lumen of neural tube|neurocoel|neural tube neural lumen|prosencoel|neural lumen|cavity of neural tube|central lumen http://purl.obolibrary.org/obo/UBERON_0003842 CHEBI:36474 biolink:ChemicalSubstance drimane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36474 chebi_ph7_3 UBERON:0003840 biolink:AnatomicalEntity hindlimb joint A limb joint that is part of a hindlimb [Automatically generated definition]. go-plus.json joint of limb of inferior member|hindlimb joint of limb|limb joint of hindlimb|joint of limb of hind limb|joint of limb of lower extremity|lower extremity limb joint|joint of lower limb|hind limb limb joint|inferior member joint of limb|hind limb joint of limb|inferior member limb joint|lower extremity joint of limb|limb joint of inferior member|joint of limb of hindlimb|limb joint of hind limb|hindlimb limb joint|joint of free lower limb|limb joint of lower extremity http://purl.obolibrary.org/obo/UBERON_0003840 CHEBI:36475 biolink:ChemicalSubstance 1-oleoylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36475 CHEBI:36473 biolink:ChemicalSubstance gammacerane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36473 chebi_ph7_3 GO:0035809 biolink:BiologicalProcess regulation of urine volume Any process that modulates the amount of urine excreted from the body over a unit of time. go-plus.json regulation of urinary volume|regulation of urine flow http://purl.obolibrary.org/obo/GO_0035809 UBERON:0003829 biolink:AnatomicalEntity urethra muscle tissue Any muscle tissue that is part of the urethra. go-plus.json urethral muscle layer http://purl.obolibrary.org/obo/UBERON_0003829 GO:0060809 biolink:BiologicalProcess mesodermal to mesenchymal transition involved in gastrulation The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0060809 UBERON:0003827 biolink:AnatomicalEntity thoracic segment bone A bone that is part of a thorax [Automatically generated definition]. go-plus.json bone organ of thorax|thorax bone organ|upper body bone|bone of thorax|thorax bone http://purl.obolibrary.org/obo/UBERON_0003827 UBERON:0003828 biolink:AnatomicalEntity abdominal segment bone A bone that is part of an abdominal segment of trunk [Automatically generated definition]. go-plus.json bone of abdominal segment of trunk|abdominal segment of trunk bone organ|bone organ of abdominal segment of trunk|abdominal segment of trunk bone http://purl.obolibrary.org/obo/UBERON_0003828 UBERON:0003825 biolink:AnatomicalEntity nerve of abdominal segment A nerve that is part of an abdominal segment of trunk [Automatically generated definition]. go-plus.json abdominal segment nerve http://purl.obolibrary.org/obo/UBERON_0003825 UBERON:0003826 biolink:AnatomicalEntity upper leg bone A bone that is part of a hindlimb stylopod [Automatically generated definition]. go-plus.json femur http://purl.obolibrary.org/obo/UBERON_0003826 UBERON:0003823 biolink:AnatomicalEntity hindlimb zeugopod The middle limb segment of the pelvic free limb, between the autopod and stylopod segments. Includes as parts the hindlimb zeugopodial skeleton, which includes as parts the tibia and fibula, or their cartilage precursors, or evolutionary variants. go-plus.json posterior part of leg|sura|posterior region of leg|intermediate segment of free lower limb|lower leg|regio surae|calf of leg|crus|hind limb zeudopodium|hind epipodium|hind limb middle limb segment|hindlimb zeugopod|leg|shank|posterior leg region|lower extremity middle limb segment|zeugopod of hindlimb|hindlimb epipodium|middle limb segment of hindlimb|middle limb segment of hind limb|crus of hindlimb|zeugopod of hind limb|lower extremity zeugopod|calf|regio cruris posterior|hindlimb zeudopodium|hindlimb middle limb segment|sural region|hind limb zeugopod|hindlimb zeugopodium|posterior curral region http://purl.obolibrary.org/obo/UBERON_0003823 UBERON:0003824 biolink:AnatomicalEntity nerve of thoracic segment A nerve that is part of a thorax [Automatically generated definition]. go-plus.json thoracic segment nerve|upper body nerve|nerve of thorax|thorax nerve http://purl.obolibrary.org/obo/UBERON_0003824 GO:0035801 biolink:BiologicalProcess adrenal cortex development The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens). go-plus.json adrenal gland cortex development http://purl.obolibrary.org/obo/GO_0035801 GO:0035802 biolink:BiologicalProcess adrenal cortex formation The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate). go-plus.json adrenal gland cortex formation http://purl.obolibrary.org/obo/GO_0035802 GO:0035803 biolink:BiologicalProcess egg coat formation Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. go-plus.json ZP assembly|zona pellucida assembly|vitelline envelope formation|VE formation http://purl.obolibrary.org/obo/GO_0035803 GO:0035804 biolink:MolecularActivity structural constituent of egg coat The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. go-plus.json structural constituent of vitelline envelope|structural constituent of zona pellucida http://purl.obolibrary.org/obo/GO_0035804 GO:0035805 biolink:CellularComponent egg coat A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. go-plus.json vitelline membrane|zona pellucida http://purl.obolibrary.org/obo/GO_0035805 CHEBI:61452 biolink:ChemicalSubstance poly(ethylene terephthalate) polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61452 GO:0035806 biolink:BiologicalProcess modulation of blood coagulation in other organism Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot. go-plus.json modulation by organism of blood coagulation in other organism|modulation by organism of blood clotting in other organism|regulation of blood clotting in other organism|regulation of blood coagulation in other organism|regulation by organism of blood clotting in other organism http://purl.obolibrary.org/obo/GO_0035806 CHEBI:85420 biolink:ChemicalSubstance N-isopropyl-L-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85420 chebi_ph7_3 GO:0035807 biolink:BiologicalProcess positive regulation of blood coagulation in other organism Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot. go-plus.json positive regulation of blood clotting in other organism|positive regulation by organism of blood clotting in other organism|positive regulation by organism of blood coagulation in other organism http://purl.obolibrary.org/obo/GO_0035807 CHEBI:61450 biolink:ChemicalSubstance (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61450 chebi_ph7_3 CHEBI:85421 biolink:ChemicalSubstance N-(gamma-L-glutamyl)-L-alaninol zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85421 chebi_ph7_3 CHEBI:61451 biolink:ChemicalSubstance (E)-3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61451 chebi_ph7_3 CHEBI:85422 biolink:ChemicalSubstance (S)-2-aminopropan-1-ol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85422 chebi_ph7_3 GO:0035808 biolink:CellularComponent meiotic recombination initiation complex A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0035808 CHEBI:36445 biolink:ChemicalSubstance alkylglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36445 CHEBI:61457 biolink:ChemicalSubstance UDP-beta-L-arabinopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61457 chebi_ph7_3 CHEBI:85424 biolink:ChemicalSubstance glycine transporter 2 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85424 CHEBI:61454 biolink:ChemicalSubstance GDP-beta-L-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61454 chebi_ph7_3 CHEBI:85425 biolink:ChemicalSubstance glycine transporter inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_85425 CHEBI:85426 biolink:ChemicalSubstance 3-phenylpropionitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_85426 chebi_ph7_3 CHEBI:61455 biolink:ChemicalSubstance UDP-beta-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61455 CHEBI:85427 biolink:ChemicalSubstance 1,2-dipalmitoyl-3-palmitoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85427 chebi_ph7_3 CHEBI:85428 biolink:ChemicalSubstance trans-3-hydroxy-L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85428 chebi_ph7_3 CHEBI:85429 biolink:ChemicalSubstance phosphatidylethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85429 GO:0060810 biolink:BiologicalProcess intracellular mRNA localization involved in pattern specification process Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo. go-plus.json intracellular mRNA localisation involved in pattern specification process http://purl.obolibrary.org/obo/GO_0060810 GO:0060811 biolink:BiologicalProcess intracellular mRNA localization involved in anterior/posterior axis specification Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis. go-plus.json intracellular mRNA localisation involved in anterior/posterior axis specification http://purl.obolibrary.org/obo/GO_0060811 GO:0035800 biolink:MolecularActivity deubiquitinase activator activity Binds to and increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences. go-plus.json http://purl.obolibrary.org/obo/GO_0035800 UBERON:0003832 biolink:AnatomicalEntity esophagus muscle Any muscle organ that is part of a esophagus [Automatically generated definition]. go-plus.json esophageal muscle|muscle organ of oesophagus|oesophagus muscle organ|muscle organ of esophagus|muscle organ of gullet|gullet muscle organ|esophagus muscle organ http://purl.obolibrary.org/obo/UBERON_0003832 GO:0060812 biolink:BiologicalProcess orthodenticle mRNA localization Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis. go-plus.json orthodenticle mRNA localisation http://purl.obolibrary.org/obo/GO_0060812 UBERON:0003833 biolink:AnatomicalEntity abdominal segment muscle A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]. go-plus.json abdominal segment of trunk muscle organ|muscle organ of abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0003833 GO:0060813 biolink:BiologicalProcess anterior mRNA localization involved in anterior/posterior axis specification Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis. go-plus.json anterior mRNA localisation involved in anterior/posterior axis specification http://purl.obolibrary.org/obo/GO_0060813 GO:0060814 biolink:BiologicalProcess posterior mRNA localization involved in anterior/posterior axis specification Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis. go-plus.json posterior mRNA localisation involved in anterior/posterior axis specification http://purl.obolibrary.org/obo/GO_0060814 UBERON:0003830 biolink:AnatomicalEntity thoracic segment muscle Any muscle organ that is part of a thorax [Automatically generated definition]. go-plus.json muscle organ of thorax|thorax muscle organ|upper body muscle http://purl.obolibrary.org/obo/UBERON_0003830 UBERON:0003831 biolink:AnatomicalEntity respiratory system muscle Any muscle organ that is part of a respiratory system [Automatically generated definition]. go-plus.json respiratory system muscle organ|muscle organ of respiratory system|muscle organ of apparatus respiratorius|apparatus respiratorius muscle organ http://purl.obolibrary.org/obo/UBERON_0003831 GO:0060815 biolink:BiologicalProcess regulation of translation involved in anterior/posterior axis specification Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0060815 GO:0060816 biolink:BiologicalProcess random inactivation of X chromosome Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex. go-plus.json http://purl.obolibrary.org/obo/GO_0060816 GO:0060817 biolink:BiologicalProcess inactivation of paternal X chromosome Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex. go-plus.json http://purl.obolibrary.org/obo/GO_0060817 GO:0060818 biolink:BiologicalProcess inactivation of paternal X chromosome by genetic imprinting Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting. go-plus.json http://purl.obolibrary.org/obo/GO_0060818 GO:0060819 biolink:BiologicalProcess inactivation of X chromosome by genetic imprinting Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting. go-plus.json http://purl.obolibrary.org/obo/GO_0060819 CHEBI:131708 biolink:ChemicalSubstance N(omega)-(1-hydroxy-2-oxopropyl)-L-arginine residue(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131708 chebi_ph7_3 CHEBI:131709 biolink:ChemicalSubstance N(6)-(1-hydroxy-2-oxopropyl)-L-lysine residue(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131709 chebi_ph7_3 CHEBI:131701 biolink:ChemicalSubstance poly(ethylene terephthalate)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131701 chebi_ph7_3 CHEBI:61460 biolink:ChemicalSubstance UDP-beta-L-arabinofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61460 CHEBI:131702 biolink:ChemicalSubstance stigmastane derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_131702 CHEBI:131703 biolink:ChemicalSubstance stigmastane sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_131703 CHEBI:131704 biolink:ChemicalSubstance 4-[(2-hydroxyethoxy)carbonyl]benzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131704 chebi_ph7_3 CHEBI:61463 biolink:ChemicalSubstance UDP-beta-L-arabinofuranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61463 chebi_ph7_3 CHEBI:131705 biolink:ChemicalSubstance 2'-deoxynucleoside 3'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131705 chebi_ph7_3 CHEBI:131706 biolink:ChemicalSubstance (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131706 chebi_ph7_3 CHEBI:131707 biolink:ChemicalSubstance (4S,5R)-4,5,6-trihydroxy-2-iminohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_131707 chebi_ph7_3 CHEBI:85411 biolink:ChemicalSubstance sn-glycero-3-phosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85411 CHEBI:61462 biolink:ChemicalSubstance (E)-3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61462 CHEBI:85412 biolink:ChemicalSubstance mitomycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_85412 CHEBI:36456 biolink:ChemicalSubstance homoisocitrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36456 CHEBI:61467 biolink:ChemicalSubstance (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61467 CHEBI:85413 biolink:ChemicalSubstance 5-hydroxyectoine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85413 chebi_ph7_3 CHEBI:36457 biolink:ChemicalSubstance homocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36457 chebi_ph7_3 CHEBI:85414 biolink:ChemicalSubstance (6S)-5,6,7,8-tetrahydropteroate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85414 chebi_ph7_3 CHEBI:36454 biolink:ChemicalSubstance isocitrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36454 CHEBI:85415 biolink:ChemicalSubstance (Z)-hex-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85415 chebi_ph7_3 CHEBI:36455 biolink:ChemicalSubstance homoisocitrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36455 CHEBI:85416 biolink:ChemicalSubstance mitomycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_85416 CHEBI:85417 biolink:ChemicalSubstance dTDP-beta-L-daunosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85417 chebi_ph7_3 CHEBI:36458 biolink:ChemicalSubstance homocitrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36458 CHEBI:85418 biolink:ChemicalSubstance 7-demethylmitomycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_85418 CHEBI:61469 biolink:ChemicalSubstance polyanionic polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_61469 GO:0060800 biolink:BiologicalProcess regulation of cell differentiation involved in embryonic placenta development Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060800 CHEBI:36459 biolink:ChemicalSubstance homocitrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36459 CHEBI:85419 biolink:ChemicalSubstance 7-demethylmitomycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_85419 UBERON:0003821 biolink:AnatomicalEntity metapodium bone A bone of the metapodial skeleton go-plus.json metapodial bone|metacarpal/metatarsal bone|metapodium bone|metacarpal/metatarsal|metacarpal or metatarsal bone|metapodi bone http://purl.obolibrary.org/obo/UBERON_0003821 GO:0060801 biolink:BiologicalProcess negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast. go-plus.json negative regulation of trophoblast cell differentiation by transforming growth factor beta signalling pathway http://purl.obolibrary.org/obo/GO_0060801 UBERON:0003822 biolink:AnatomicalEntity forelimb stylopod The part of the forelimb between pectoral region and the elbow, corresponding to the humerus. go-plus.json proximal segment of free upper limb|regio brachialis|brachium|stylopod of arm|fore propodium|forelimb stylopodium|wing stylopod|stylopod of forelimb|upper arm|arm|forelimb propodium|brachial region|forelimb stylopodial element http://purl.obolibrary.org/obo/UBERON_0003822 GO:0060802 biolink:BiologicalProcess epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis. go-plus.json epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification http://purl.obolibrary.org/obo/GO_0060802 GO:0060803 biolink:BiologicalProcess BMP signaling pathway involved in mesodermal cell fate specification A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate. go-plus.json BMP signalling pathway involved in mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0060803 GO:0060804 biolink:BiologicalProcess positive regulation of Wnt signaling pathway by BMP signaling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway. go-plus.json positive regulation of WNT receptor signaling pathway by BMP signaling pathway|positive regulation of Wnt-activated signaling pathway by BMP signaling pathway|positive regulation of Wnt receptor signaling pathway by BMP signaling pathway|positive regulation of WNT receptor signalling pathway by BMP signalling pathway http://purl.obolibrary.org/obo/GO_0060804 UBERON:0003820 biolink:AnatomicalEntity prostate bud A region of the fetal urogenital sinus epithelium destined to become the prostate[GO]. go-plus.json prostatic bud|prostate ductal progenitor|prostate gland bud|prostate primordium http://purl.obolibrary.org/obo/UBERON_0003820 GO:0060805 biolink:BiologicalProcess negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast. go-plus.json http://purl.obolibrary.org/obo/GO_0060805 CHEBI:36452 biolink:ChemicalSubstance aralkylglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36452 GO:0060806 biolink:BiologicalProcess negative regulation of cell differentiation involved in embryonic placenta development Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060806 CHEBI:36453 biolink:ChemicalSubstance isocitrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36453 GO:0060807 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060807 CHEBI:36451 biolink:ChemicalSubstance alkenylglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36451 GO:0060808 biolink:BiologicalProcess positive regulation of mesodermal to mesenchymal transition involved in gastrulation Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0060808 UBERON:0003889 biolink:AnatomicalEntity fallopian tube Initial section of the oviduct through which the ova pass from the ovary to the uterus go-plus.json tuba uterina|paramesonephric duct of female|female paramesonephric duct|fallopian tubes|mammalian oviduct|uterine tube (sensu Mammalia)|salpinx|salpinges http://purl.obolibrary.org/obo/UBERON_0003889 CHEBI:61470 biolink:ChemicalSubstance (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61470 CHEBI:85440 biolink:ChemicalSubstance very long-chain (R)-3-hydroxyacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85440 chebi_ph7_3 CHEBI:85442 biolink:ChemicalSubstance trans-3-hexenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85442 CHEBI:61472 biolink:ChemicalSubstance all-trans-6-methoxy-2-hexaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_61472 chebi_ph7_3 CHEBI:85443 biolink:ChemicalSubstance (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85443 CHEBI:61473 biolink:ChemicalSubstance all-trans-5-methoxy-2-methyl-3-hexaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_61473 chebi_ph7_3 CHEBI:61478 biolink:ChemicalSubstance germacrene C go-plus.json http://purl.obolibrary.org/obo/CHEBI_61478 chebi_ph7_3 CHEBI:36423 biolink:ChemicalSubstance 1H-carbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36423 chebi_ph7_3 CHEBI:85445 biolink:ChemicalSubstance 2'-deoxyguanosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85445 chebi_ph7_3 UBERON:0003890 biolink:AnatomicalEntity Mullerian duct paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]. go-plus.json Müllerian duct|ductus paramesonephricus|early paramesonephric duct|paramesonephric duct|Muellerian duct http://purl.obolibrary.org/obo/UBERON_0003890 UBERON:0003891 biolink:AnatomicalEntity stroma Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma. go-plus.json stromal connective tissue http://purl.obolibrary.org/obo/UBERON_0003891 CHEBI:36424 biolink:ChemicalSubstance 4aH-carbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36424 CHEBI:36422 biolink:ChemicalSubstance 3H-carbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36422 CHEBI:85448 biolink:ChemicalSubstance 6-O-methyl dGMP(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85448 chebi_ph7_3 GO:0060830 biolink:BiologicalProcess ciliary receptor clustering involved in smoothened signaling pathway Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway. go-plus.json ciliary receptor clustering involved in smoothened signalling pathway|ciliary receptor clustering involved in hh signaling pathway|ciliary receptor clustering involved in hedgehog signaling pathway http://purl.obolibrary.org/obo/GO_0060830 CHEBI:85449 biolink:ChemicalSubstance O-tetradecenoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85449 chebi_ph7_3 GO:0060831 biolink:BiologicalProcess smoothened signaling pathway involved in dorsal/ventral neural tube patterning The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube. go-plus.json hh signaling pathway involved in dorsal/ventral neural tube patterning|hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|smoothened signalling pathway involved in dorsal/ventral neural tube patterning http://purl.obolibrary.org/obo/GO_0060831 CHEBI:36425 biolink:ChemicalSubstance 8aH-carbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_36425 chebi_ph7_3 GO:0060832 biolink:BiologicalProcess oocyte animal/vegetal axis specification The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0060832 GO:0060833 biolink:BiologicalProcess Wnt signaling pathway involved in animal/vegetal axis specification The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte. go-plus.json Wnt- activated signaling pathway involved in animal/vegetal axis specification|Wnt receptor signalling pathway involved in animal/vegetal axis specification|Wnt receptor signaling pathway involved in animal/vegetal axis specification http://purl.obolibrary.org/obo/GO_0060833 UBERON:0003898 biolink:AnatomicalEntity skeletal muscle tissue of trunk A portion of skeletal muscle tissue in the trunk. go-plus.json skeletal muscle of torso|trunk skeletal muscle|torso skeletal muscle|skeletal muscle tissue of trunk|skeletal muscle tissue of torso|torso skeletal muscle tissue|trunk skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0003898 GO:0060834 biolink:BiologicalProcess oral/aboral axis specification The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo. go-plus.json oral/aboral axis determination http://purl.obolibrary.org/obo/GO_0060834 GO:0060835 biolink:BiologicalProcess transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis. go-plus.json transforming growth factor receptor beta signalling pathway involved in oral/aboral axis specification http://purl.obolibrary.org/obo/GO_0060835 GO:0060836 biolink:BiologicalProcess lymphatic endothelial cell differentiation The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0060836 GO:0060837 biolink:BiologicalProcess blood vessel endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0060837 UBERON:0003897 biolink:AnatomicalEntity axial muscle One of the skeletal muscles of the head and neck, spine, and ribs. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003897 GO:0060838 biolink:BiologicalProcess lymphatic endothelial cell fate commitment The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060838 UBERON:0003894 biolink:AnatomicalEntity liver primordium A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum. go-plus.json liver bud|hepatic plate|embryological hepatic plate|primordium of the liver|liver endoderm http://purl.obolibrary.org/obo/UBERON_0003894 GO:0060839 biolink:BiologicalProcess endothelial cell fate commitment The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060839 CHEBI:36420 biolink:ChemicalSubstance acridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36420 chebi_ph7_3 UBERON:0003893 biolink:AnatomicalEntity capsule A cover or envelope partly or wholly surrounding a structure. Examples: egg shell, articular capsules, renal capsules[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003893 GO:0045204 biolink:BiologicalProcess MAPK export from nucleus The directed movement of a MAP kinase from the nucleus to the cytoplasm. go-plus.json cytoplasmic translocation of MAP kinase|cytoplasmic translocation of mitogen-activated protein kinase|MAPK export from cell nucleus|MAPK transport from nucleus to cytoplasm|MAPK-nucleus export|MAPK export out of nucleus http://purl.obolibrary.org/obo/GO_0045204 CHEBI:61481 biolink:ChemicalSubstance dCTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61481 chebi_ph7_3 GO:0045205 biolink:MolecularActivity obsolete MAPK transporter activity OBSOLETE. Enables the directed movement of MAP kinase into, out of or within a cell, or between cells. go-plus.json MAPK transporter activity http://purl.obolibrary.org/obo/GO_0045205 GO:0045202 biolink:CellularComponent synapse The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. NIF_Subcellular:sao914572699|Wikipedia:Chemical_synapse go-plus.json electrotonic synapse|synaptic junction|mixed synapse http://purl.obolibrary.org/obo/GO_0045202 goslim_mouse|goslim_agr|goslim_synapse|goslim_pir|goslim_drosophila|goslim_flybase_ribbon GO:0045203 biolink:CellularComponent integral component of cell outer membrane The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to external membrane|integral to cell outer membrane|integral to outer membrane http://purl.obolibrary.org/obo/GO_0045203 GO:0045200 biolink:BiologicalProcess establishment of neuroblast polarity The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. go-plus.json establishment of neuroblast cell polarity http://purl.obolibrary.org/obo/GO_0045200 CHEBI:85430 biolink:ChemicalSubstance 11-deoxy-beta-rhodomycin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85430 chebi_ph7_3 GO:0045201 biolink:BiologicalProcess maintenance of neuroblast polarity The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. go-plus.json maintenance of neuroblast cell polarity http://purl.obolibrary.org/obo/GO_0045201 CHEBI:85433 biolink:ChemicalSubstance glutamine hydroxamate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85433 chebi_ph7_3 CHEBI:36434 biolink:ChemicalSubstance octadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36434 chebi_ph7_3 CHEBI:36432 biolink:ChemicalSubstance 2-methylbut-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36432 CHEBI:36438 biolink:ChemicalSubstance (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36438 chebi_ph7_3 GO:0045208 biolink:BiologicalProcess MAPK phosphatase export from nucleus The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm. go-plus.json MAPK phosphatase-nucleus export|MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase export from cell nucleus|MAPK phosphatase export out of nucleus http://purl.obolibrary.org/obo/GO_0045208 GO:0045209 biolink:BiologicalProcess MAPK phosphatase export from nucleus, leptomycin B sensitive Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm. go-plus.json leptomycin B-sensitive MAPK phosphatase export out of nucleus|MAPK phosphatase-nucleus export, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase-nucleus export|MAPK phosphatase transport from nucleus to cytoplasm, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase export from cell nucleus, leptomycin B sensitive|MAPK phosphatase export out of nucleus, leptomycin B sensitive http://purl.obolibrary.org/obo/GO_0045209 GO:0060820 biolink:BiologicalProcess inactivation of X chromosome by heterochromatin assembly Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation. go-plus.json inactivation of X chromosome by heterochromatin formation http://purl.obolibrary.org/obo/GO_0060820 CHEBI:85439 biolink:ChemicalSubstance trans,trans-2,4-hexadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85439 GO:0060821 biolink:BiologicalProcess obsolete inactivation of X chromosome by DNA methylation OBSOLETE. Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0060821 GO:0045206 biolink:MolecularActivity obsolete MAPK phosphatase transporter activity OBSOLETE. Enables the directed movement of MAPK phosphatase into, out of or within a cell, or between cells. go-plus.json MKP shuttle|leptomycin B-sensitive MKP shuttle|MAPK phosphatase transporter activity|leptomycin B-sensitive MAPK phosphatase transporter activity http://purl.obolibrary.org/obo/GO_0045206 GO:0060822 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate. go-plus.json transforming growth factor beta receptor signalling pathway involved in axial mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0060822 GO:0045207 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045207 GO:0060823 biolink:BiologicalProcess canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern. go-plus.json canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation|Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0060823 UBERON:0003887 biolink:AnatomicalEntity intraembryonic coelom The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom go-plus.json somatic coelom http://purl.obolibrary.org/obo/UBERON_0003887 GO:0060824 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate. go-plus.json retinoic acid receptor signalling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0060824 GO:0060825 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate. go-plus.json fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0060825 UBERON:0003885 biolink:AnatomicalEntity mesometrium A mesentery that is part of a uterus [Automatically generated definition]. go-plus.json mesentery of uterus http://purl.obolibrary.org/obo/UBERON_0003885 UBERON:0003886 biolink:AnatomicalEntity future coelemic cavity lumen An anatomical cavity that has the potential to develop into a coelemic cavity lumen. go-plus.json body cavity precursor http://purl.obolibrary.org/obo/UBERON_0003886 GO:0060826 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern. go-plus.json transforming growth factor beta receptor signalling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0060826 GO:0060827 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern. go-plus.json regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0060827 GO:0060828 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json regulation of canonical Wnt receptor signalling pathway|regulation of catenin import into nucleus|regulation of canonical Wnt receptor signaling pathway|regulation of canonical Wnt-activated signaling pathway|regulation of catenin protein nuclear translocation|catenin import into nucleus|regulation of Wnt receptor signaling pathway through beta-catenin http://purl.obolibrary.org/obo/GO_0060828 GO:0060829 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis. go-plus.json negative regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0060829 GO:1901707 biolink:MolecularActivity leptomycin B binding Binding to leptomycin B. go-plus.json http://purl.obolibrary.org/obo/GO_1901707 GO:1901708 biolink:BiologicalProcess (+)-3'-hydroxylarreatricin biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin. go-plus.json (+)-3'-hydroxylarreatricin synthesis|(+)-3'-hydroxylarreatricin biosynthesis|(+)-3'-hydroxylarreatricin formation|(+)-3'-hydroxylarreatricin anabolism http://purl.obolibrary.org/obo/GO_1901708 GO:1901705 biolink:BiologicalProcess L-isoleucine biosynthetic process The chemical reactions and pathways resulting in the formation of L-isoleucine. go-plus.json L-isoleucine biosynthesis|L-isoleucine anabolism|L-isoleucine synthesis|L-isoleucine formation http://purl.obolibrary.org/obo/GO_1901705 GO:1901706 biolink:BiologicalProcess mesenchymal cell differentiation involved in bone development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_1901706 GO:1901703 biolink:BiologicalProcess protein localization involved in auxin polar transport Any protein localization that is involved in auxin polar transport. go-plus.json establishment and maintenance of protein localization involved in auxin polar transport|protein localisation involved in auxin polar transport http://purl.obolibrary.org/obo/GO_1901703 UBERON:0003869 biolink:AnatomicalEntity presumptive ganglion A presumptive structure that has the potential to develop into a ganglion. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003869 GO:1901704 biolink:BiologicalProcess L-glutamine biosynthetic process The chemical reactions and pathways resulting in the formation of L-glutamine. go-plus.json L-glutamine formation|L-glutamine biosynthesis|L-glutamine anabolism|L-glutamine synthesis http://purl.obolibrary.org/obo/GO_1901704 GO:1901701 biolink:BiologicalProcess cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. go-plus.json cellular response to oxygen molecular entity http://purl.obolibrary.org/obo/GO_1901701 UBERON:0003867 biolink:AnatomicalEntity distal phalanx of pes A distal phalanx that is part of a pedal digit [Automatically generated definition]. go-plus.json ungual phalanx of hindlimb|phalanx distalis pedis|foot distal phalanx|distal phalanx of toe|terminal phalanx of foot|terminal phalanx of hindlimb|distal pedal phalanx|ungual phalanx of foot|distal phalanx of foot http://purl.obolibrary.org/obo/UBERON_0003867 UBERON:0003868 biolink:AnatomicalEntity proximal phalanx of pes A proximal phalanx that is part of a pedal digit [Automatically generated definition]. go-plus.json proximal phalanx of foot digit|proximal phalanx of toe|proximal pedal phalanx|proximal phalanx of foot|phalanx proximalis pedis|foot proximal phalanx|proximal phalanx of pes|proximal phalanx of hind digit http://purl.obolibrary.org/obo/UBERON_0003868 GO:1901702 biolink:MolecularActivity salt transmembrane transporter activity Enables the transfer of salt from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901702 GO:0045215 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045215 GO:1901700 biolink:BiologicalProcess response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. go-plus.json response to oxygen molecular entity http://purl.obolibrary.org/obo/GO_1901700 GO:0045216 biolink:BiologicalProcess cell-cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. go-plus.json intercellular junction assembly and maintenance|cell-cell junction biogenesis|cell-cell junction organisation|cell-cell junction assembly and maintenance http://purl.obolibrary.org/obo/GO_0045216 GO:0045213 biolink:BiologicalProcess neurotransmitter receptor metabolic process The chemical reactions and pathways involving neurotransmitter receptors. go-plus.json neurotransmitter receptor metabolism http://purl.obolibrary.org/obo/GO_0045213 GO:0045214 biolink:BiologicalProcess sarcomere organization The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. go-plus.json sarcomere organisation|sarcomere alignment http://purl.obolibrary.org/obo/GO_0045214 CHEBI:36408 biolink:ChemicalSubstance 5-hydroxy-L-kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36408 CHEBI:61496 biolink:ChemicalSubstance alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61496 chebi_ph7_3 GO:0045211 biolink:CellularComponent postsynaptic membrane A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. go-plus.json post-synaptic membrane http://purl.obolibrary.org/obo/GO_0045211 goslim_synapse GO:0045212 biolink:BiologicalProcess obsolete neurotransmitter receptor biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitter receptors. go-plus.json neurotransmitter receptor anabolism|neurotransmitter receptor synthesis|neurotransmitter receptor formation|neurotransmitter receptor biosynthesis http://purl.obolibrary.org/obo/GO_0045212 CHEBI:61494 biolink:ChemicalSubstance UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61494 chebi_ph7_3 CHEBI:61495 biolink:ChemicalSubstance beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61495 chebi_ph7_3 GO:0045210 biolink:BiologicalProcess FasL biosynthetic process The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines. go-plus.json fas ligand biosynthetic process|FasL biosynthesis|APT1LG1 biosynthetic process|CD95L biosynthesis|CD95L biosynthetic process|FasL anabolism|CD178 biosynthetic process|FASLG biosynthetic process|FasL synthesis|FasL formation|Fas-L biosynthetic process http://purl.obolibrary.org/obo/GO_0045210 CHEBI:36401 biolink:ChemicalSubstance cycloalkadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36401 CHEBI:85468 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85468 chebi_ph7_3 CHEBI:36402 biolink:ChemicalSubstance cycloalkatriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36402 GO:0060850 biolink:BiologicalProcess obsolete regulation of transcription involved in cell fate commitment OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060850 CHEBI:61498 biolink:ChemicalSubstance epoxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61498 GO:0060851 biolink:BiologicalProcess vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate. go-plus.json vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment http://purl.obolibrary.org/obo/GO_0060851 CHEBI:36405 biolink:ChemicalSubstance 2-aminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36405 GO:0045219 biolink:BiologicalProcess regulation of FasL production Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL. go-plus.json regulation of FasL biosynthesis|regulation of FasL anabolism|regulation of FasL synthesis|regulation of FasL formation http://purl.obolibrary.org/obo/GO_0045219 GO:0060852 biolink:BiologicalProcess obsolete regulation of transcription involved in venous endothelial cell fate commitment OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060852 GO:0060853 biolink:BiologicalProcess Notch signaling pathway involved in arterial endothelial cell fate commitment The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate. go-plus.json Notch signalling pathway involved in arterial endothelial cell fate commitment http://purl.obolibrary.org/obo/GO_0060853 GO:0045217 biolink:BiologicalProcess cell-cell junction maintenance The maintenance of junctions between cells. go-plus.json intercellular junction maintenance http://purl.obolibrary.org/obo/GO_0045217 GO:0060854 biolink:BiologicalProcess branching involved in lymph vessel morphogenesis The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system. go-plus.json patterning of lymph vessels http://purl.obolibrary.org/obo/GO_0060854 CHEBI:36403 biolink:ChemicalSubstance monocyclic olefin go-plus.json http://purl.obolibrary.org/obo/CHEBI_36403 GO:0045218 biolink:BiologicalProcess zonula adherens maintenance Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0045218 GO:0060855 biolink:BiologicalProcess venous endothelial cell migration involved in lymph vessel development The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060855 CHEBI:36404 biolink:ChemicalSubstance cyclohexene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36404 chebi_ph7_3 GO:0060856 biolink:BiologicalProcess establishment of blood-brain barrier Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. go-plus.json establishment of blood/brain barrier|establishment of BBB http://purl.obolibrary.org/obo/GO_0060856 GO:0060857 biolink:BiologicalProcess establishment of glial blood-brain barrier Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. go-plus.json establishment of glial BBB|establishment of glial blood/brain barrier http://purl.obolibrary.org/obo/GO_0060857 GO:0060858 biolink:BiologicalProcess vesicle-mediated transport involved in floral organ abscission The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ. go-plus.json membrane trafficking involved in floral organ shedding http://purl.obolibrary.org/obo/GO_0060858 GO:0060859 biolink:BiologicalProcess obsolete regulation of vesicle-mediated transport involved in floral organ abscission OBSOLETE. Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ. go-plus.json http://purl.obolibrary.org/obo/GO_0060859 GO:1901709 biolink:BiologicalProcess (+)-larreatricin metabolic process The chemical reactions and pathways involving (+)-larreatricin. go-plus.json (+)-larreatricin metabolism http://purl.obolibrary.org/obo/GO_1901709 GO:1901718 biolink:BiologicalProcess obsolete regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of dipeptide transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1901718 GO:1901719 biolink:BiologicalProcess regulation of NMS complex assembly Any process that modulates the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation. go-plus.json regulation of KMN network assembly involved in chromosome segregation|regulation of NMS complex association involved in chromosome segregation|regulation of NMS complex assembly involved in kinetochore assembly|regulation of KMN complex assembly involved in chromosome segregation http://purl.obolibrary.org/obo/GO_1901719 GO:1901716 biolink:BiologicalProcess negative regulation of gamma-aminobutyric acid catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. go-plus.json downregulation of 4-aminobutanoate catabolism|downregulation of gamma-aminobutyric acid breakdown|down regulation of gamma-aminobutyric acid catabolic process|inhibition of GABA catabolism|down-regulation of gamma-aminobutyric acid catabolism|negative regulation of gamma-aminobutyric acid catabolism|downregulation of GABA catabolic process|down regulation of 4-aminobutyrate catabolic process|down-regulation of gamma-aminobutyric acid degradation|negative regulation of gamma-aminobutyric acid degradation|downregulation of gamma-aminobutyric acid catabolic process|downregulation of 4-aminobutyrate catabolism|negative regulation of 4-aminobutanoate catabolic process|down regulation of GABA catabolic process|down-regulation of 4-aminobutanoate catabolic process|down regulation of GABA catabolism|negative regulation of 4-aminobutanoate catabolism|downregulation of 4-aminobutyrate catabolic process|down-regulation of 4-aminobutanoate catabolism|down-regulation of gamma-aminobutyric acid breakdown|negative regulation of gamma-aminobutyric acid breakdown|down regulation of 4-aminobutyrate catabolism|downregulation of gamma-aminobutyric acid catabolism|downregulation of GABA catabolism|inhibition of GABA catabolic process|down-regulation of gamma-aminobutyric acid catabolic process|down regulation of gamma-aminobutyric acid catabolism|downregulation of 4-aminobutanoate catabolic process|inhibition of gamma-aminobutyric acid degradation|negative regulation of 4-aminobutyrate catabolic process|inhibition of 4-aminobutyrate catabolism|down-regulation of 4-aminobutyrate catabolic process|down regulation of 4-aminobutanoate catabolic process|inhibition of gamma-aminobutyric acid catabolic process|inhibition of 4-aminobutanoate catabolism|inhibition of gamma-aminobutyric acid breakdown|negative regulation of GABA catabolism|inhibition of gamma-aminobutyric acid catabolism|down-regulation of GABA catabolism|down regulation of gamma-aminobutyric acid degradation|negative regulation of GABA catabolic process|down-regulation of GABA catabolic process|inhibition of 4-aminobutanoate catabolic process|down regulation of 4-aminobutanoate catabolism|downregulation of gamma-aminobutyric acid degradation|down regulation of gamma-aminobutyric acid breakdown|down-regulation of 4-aminobutyrate catabolism|inhibition of 4-aminobutyrate catabolic process|negative regulation of 4-aminobutyrate catabolism http://purl.obolibrary.org/obo/GO_1901716 GO:1901717 biolink:BiologicalProcess positive regulation of gamma-aminobutyric acid catabolic process Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. go-plus.json positive regulation of GABA catabolic process|upregulation of gamma-aminobutyric acid catabolic process|up regulation of gamma-aminobutyric acid degradation|up-regulation of 4-aminobutanoate catabolic process|up regulation of GABA catabolic process|activation of gamma-aminobutyric acid catabolism|positive regulation of gamma-aminobutyric acid degradation|upregulation of 4-aminobutyrate catabolic process|positive regulation of 4-aminobutyrate catabolism|up regulation of 4-aminobutanoate catabolism|up regulation of 4-aminobutyrate catabolism|up regulation of gamma-aminobutyric acid breakdown|positive regulation of 4-aminobutanoate catabolism|upregulation of GABA catabolism|activation of gamma-aminobutyric acid degradation|activation of 4-aminobutanoate catabolic process|positive regulation of gamma-aminobutyric acid catabolism|positive regulation of gamma-aminobutyric acid breakdown|up regulation of gamma-aminobutyric acid catabolic process|up regulation of gamma-aminobutyric acid catabolism|activation of gamma-aminobutyric acid catabolic process|upregulation of GABA catabolic process|activation of 4-aminobutanoate catabolism|activation of gamma-aminobutyric acid breakdown|positive regulation of 4-aminobutanoate catabolic process|up-regulation of gamma-aminobutyric acid degradation|up regulation of 4-aminobutyrate catabolic process|up regulation of 4-aminobutanoate catabolic process|positive regulation of 4-aminobutyrate catabolic process|upregulation of 4-aminobutyrate catabolism|up regulation of GABA catabolism|up-regulation of 4-aminobutanoate catabolism|up-regulation of gamma-aminobutyric acid breakdown|positive regulation of GABA catabolism|upregulation of gamma-aminobutyric acid catabolism|activation of 4-aminobutyrate catabolic process|up-regulation of GABA catabolic process|up-regulation of gamma-aminobutyric acid catabolic process|upregulation of gamma-aminobutyric acid degradation|upregulation of 4-aminobutanoate catabolic process|up-regulation of 4-aminobutyrate catabolism|activation of GABA catabolism|up-regulation of 4-aminobutyrate catabolic process|activation of GABA catabolic process|upregulation of 4-aminobutanoate catabolism|upregulation of gamma-aminobutyric acid breakdown|up-regulation of gamma-aminobutyric acid catabolism|activation of 4-aminobutyrate catabolism|up-regulation of GABA catabolism http://purl.obolibrary.org/obo/GO_1901717 GO:1901714 biolink:BiologicalProcess positive regulation of urea catabolic process Any process that activates or increases the frequency, rate or extent of urea catabolic process. go-plus.json up regulation of urea catabolic process|upregulation of urea degradation|upregulation of urea catabolism|upregulation of urea breakdown|up-regulation of urea decomposition|upregulation of urea catabolic process|up-regulation of urea degradation|activation of urea decomposition|up-regulation of urea breakdown|up regulation of urea catabolism|activation of urea degradation|positive regulation of urea decomposition|positive regulation of urea catabolism|up-regulation of urea catabolic process|up regulation of urea decomposition|activation of urea catabolic process|positive regulation of urea degradation|activation of urea breakdown|up regulation of urea degradation|activation of urea catabolism|positive regulation of urea breakdown|up regulation of urea breakdown|up-regulation of urea catabolism|upregulation of urea decomposition http://purl.obolibrary.org/obo/GO_1901714 GO:1901715 biolink:BiologicalProcess regulation of gamma-aminobutyric acid catabolic process Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. go-plus.json regulation of gamma-aminobutyric acid breakdown|regulation of GABA catabolic process|regulation of 4-aminobutyrate catabolic process|regulation of 4-aminobutyrate catabolism|regulation of GABA catabolism|regulation of gamma-aminobutyric acid catabolism|regulation of 4-aminobutanoate catabolic process|regulation of gamma-aminobutyric acid degradation|regulation of 4-aminobutanoate catabolism http://purl.obolibrary.org/obo/GO_1901715 UBERON:0003859 biolink:AnatomicalEntity forelimb mesenchyme Mesenchyme that is part of a developing forelimb [Automatically generated definition]. go-plus.json superior member mesenchyme|mesenchyme of forelimb|mesenchyme of superior member|fore limb mesenchyme|anteriormost limb mesenchyme|upper extremity mesenchyme|mesenchyme of anteriormost limb|mesenchyme of upper extremity|mesenchyme of fore limb|wing mesenchyme http://purl.obolibrary.org/obo/UBERON_0003859 GO:1901712 biolink:BiologicalProcess positive regulation of homoserine biosynthetic process Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process. go-plus.json up regulation of homoserine biosynthesis|up regulation of homoserine biosynthetic process|upregulation of homoserine synthesis|positive regulation of homoserine biosynthesis|activation of homoserine biosynthetic process|upregulation of homoserine formation|up-regulation of homoserine anabolism|activation of homoserine biosynthesis|up-regulation of homoserine synthesis|activation of homoserine anabolism|up-regulation of homoserine formation|up-regulation of homoserine biosynthetic process|up-regulation of homoserine biosynthesis|activation of homoserine synthesis|positive regulation of homoserine anabolism|activation of homoserine formation|up regulation of homoserine anabolism|positive regulation of homoserine synthesis|up regulation of homoserine synthesis|upregulation of homoserine biosynthetic process|upregulation of homoserine biosynthesis|positive regulation of homoserine formation|up regulation of homoserine formation|upregulation of homoserine anabolism http://purl.obolibrary.org/obo/GO_1901712 UBERON:0003856 biolink:AnatomicalEntity uncondensed odontogenic mesenchyme Mesenchyme enclosed by a dental organ that gives rise to an odontogenic papilla. go-plus.json enamel organ mesenchyme|dental mesenchyme|dental organ mesenchyme|tooth enamel organ mesenchyme|tooth mesenchyme http://purl.obolibrary.org/obo/UBERON_0003856 GO:1901713 biolink:BiologicalProcess negative regulation of urea catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process. go-plus.json inhibition of urea decomposition|inhibition of urea catabolism|downregulation of urea catabolic process|down regulation of urea breakdown|inhibition of urea degradation|down regulation of urea catabolic process|inhibition of urea catabolic process|down regulation of urea catabolism|inhibition of urea breakdown|downregulation of urea catabolism|negative regulation of urea decomposition|down-regulation of urea decomposition|down-regulation of urea degradation|negative regulation of urea degradation|down-regulation of urea breakdown|negative regulation of urea catabolism|negative regulation of urea breakdown|down-regulation of urea catabolism|downregulation of urea decomposition|downregulation of urea degradation|down-regulation of urea catabolic process|down regulation of urea decomposition|down regulation of urea degradation|downregulation of urea breakdown http://purl.obolibrary.org/obo/GO_1901713 GO:0045226 biolink:BiologicalProcess extracellular polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures. go-plus.json extracellular polysaccharide anabolism|extracellular polysaccharide synthesis|extracellular polysaccharide formation|extracellular polysaccharide biosynthesis http://purl.obolibrary.org/obo/GO_0045226 GO:1901710 biolink:BiologicalProcess regulation of homoserine biosynthetic process Any process that modulates the frequency, rate or extent of homoserine biosynthetic process. go-plus.json regulation of homoserine anabolism|regulation of homoserine synthesis|regulation of homoserine biosynthesis|regulation of homoserine formation http://purl.obolibrary.org/obo/GO_1901710 GO:1901711 biolink:BiologicalProcess negative regulation of homoserine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process. go-plus.json inhibition of homoserine anabolism|down regulation of homoserine formation|inhibition of homoserine synthesis|negative regulation of homoserine biosynthesis|down-regulation of homoserine biosynthetic process|down-regulation of homoserine biosynthesis|inhibition of homoserine formation|negative regulation of homoserine anabolism|down-regulation of homoserine anabolism|inhibition of homoserine biosynthetic process|down-regulation of homoserine synthesis|negative regulation of homoserine synthesis|inhibition of homoserine biosynthesis|negative regulation of homoserine formation|down-regulation of homoserine formation|downregulation of homoserine anabolism|down regulation of homoserine biosynthesis|downregulation of homoserine synthesis|down regulation of homoserine biosynthetic process|down regulation of homoserine anabolism|downregulation of homoserine formation|downregulation of homoserine biosynthesis|down regulation of homoserine synthesis|downregulation of homoserine biosynthetic process http://purl.obolibrary.org/obo/GO_1901711 GO:0045227 biolink:BiologicalProcess capsule polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi. go-plus.json capsule polysaccharide synthesis|capsule polysaccharide formation|capsule polysaccharide biosynthesis|capsular polysaccharide biosynthesis|capsular polysaccharide biosynthetic process|capsule polysaccharide anabolism http://purl.obolibrary.org/obo/GO_0045227 GO:0045224 biolink:BiologicalProcess positive regulation of CD4 production Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4. go-plus.json up regulation of CD4 biosynthetic process|positive regulation of CD4 anabolism|positive regulation of CD4 synthesis|positive regulation of CD4 formation|upregulation of CD4 biosynthetic process|stimulation of CD4 biosynthetic process|up-regulation of CD4 biosynthetic process|activation of CD4 biosynthetic process|positive regulation of CD4 biosynthetic process|positive regulation of CD4 biosynthesis http://purl.obolibrary.org/obo/GO_0045224 GO:0045225 biolink:BiologicalProcess negative regulation of CD4 production Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4. go-plus.json downregulation of CD4 biosynthetic process|negative regulation of CD4 anabolism|down regulation of CD4 biosynthetic process|inhibition of CD4 biosynthetic process|negative regulation of CD4 synthesis|negative regulation of CD4 formation|down-regulation of CD4 biosynthetic process|negative regulation of CD4 biosynthetic process|negative regulation of CD4 biosynthesis http://purl.obolibrary.org/obo/GO_0045225 GO:0045222 biolink:BiologicalProcess CD4 biosynthetic process The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions. go-plus.json CD4 anabolism|CD4 synthesis|CD4 formation|CD4 biosynthesis http://purl.obolibrary.org/obo/GO_0045222 CHEBI:85452 biolink:ChemicalSubstance 2'-deoxycytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85452 chebi_ph7_3 GO:0045223 biolink:BiologicalProcess regulation of CD4 production Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4. go-plus.json regulation of CD4 formation|regulation of CD4 biosynthetic process|regulation of CD4 biosynthesis|regulation of CD4 anabolism|regulation of CD4 synthesis http://purl.obolibrary.org/obo/GO_0045223 GO:0045220 biolink:BiologicalProcess positive regulation of FasL production Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL. go-plus.json upregulation of FasL biosynthetic process|positive regulation of FasL anabolism|positive regulation of FasL synthesis|up regulation of FasL biosynthetic process|positive regulation of FasL formation|positive regulation of FasL biosynthetic process|positive regulation of FasL biosynthesis|activation of FasL biosynthetic process|stimulation of FasL biosynthetic process|up-regulation of FasL biosynthetic process http://purl.obolibrary.org/obo/GO_0045220 CHEBI:85454 biolink:ChemicalSubstance 5-methyl dCMP(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85454 chebi_ph7_3 GO:0045221 biolink:BiologicalProcess negative regulation of FasL production Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL. go-plus.json negative regulation of FasL anabolism|down regulation of FasL biosynthetic process|negative regulation of FasL synthesis|downregulation of FasL biosynthetic process|negative regulation of FasL formation|negative regulation of FasL biosynthetic process|negative regulation of FasL biosynthesis|down-regulation of FasL biosynthetic process|inhibition of FasL biosynthetic process http://purl.obolibrary.org/obo/GO_0045221 CHEBI:36413 biolink:ChemicalSubstance anabolic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_36413 GO:0060840 biolink:BiologicalProcess artery development The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. go-plus.json http://purl.obolibrary.org/obo/GO_0060840 GO:0060841 biolink:BiologicalProcess venous blood vessel development The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. go-plus.json http://purl.obolibrary.org/obo/GO_0060841 CHEBI:36416 biolink:ChemicalSubstance mancude organic heterotricyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_36416 GO:0060842 biolink:BiologicalProcess arterial endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. go-plus.json http://purl.obolibrary.org/obo/GO_0060842 GO:0060843 biolink:BiologicalProcess venous endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. go-plus.json http://purl.obolibrary.org/obo/GO_0060843 GO:0045228 biolink:BiologicalProcess slime layer polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall. go-plus.json slime layer polysaccharide anabolism|slime layer polysaccharide synthesis|slime layer polysaccharide formation|slime layer polysaccharide biosynthesis http://purl.obolibrary.org/obo/GO_0045228 GO:0060844 biolink:BiologicalProcess arterial endothelial cell fate commitment The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060844 GO:0045229 biolink:BiologicalProcess external encapsulating structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. go-plus.json external encapsulating structure organisation|external encapsulating structure organization and biogenesis http://purl.obolibrary.org/obo/GO_0045229 goslim_pir GO:0060845 biolink:BiologicalProcess venous endothelial cell fate commitment The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060845 UBERON:0003865 biolink:AnatomicalEntity distal phalanx of manus A distal phalanx that is part of a finger [Automatically generated definition]. go-plus.json phalanx distalis manus|distal phalanx of finger|hand distal phalanx|distal manual phalanx|terminal phalanx of hand|distal phalanx of manual digit|ungual phalanx of hand|distal phalanx of hand http://purl.obolibrary.org/obo/UBERON_0003865 GO:0060846 biolink:BiologicalProcess blood vessel endothelial cell fate commitment The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060846 UBERON:0003866 biolink:AnatomicalEntity middle phalanx of pes A middle phalanx that is part of a toe [Automatically generated definition]. go-plus.json phalanx media pedis|middle phalanx of toe|middle pedal phalanx|middle phalanx of foot|foot middle phalanx http://purl.obolibrary.org/obo/UBERON_0003866 GO:0060847 biolink:BiologicalProcess endothelial cell fate specification The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060847 GO:0060848 biolink:BiologicalProcess endothelial cell fate determination A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060848 UBERON:0003864 biolink:AnatomicalEntity middle phalanx of manus A middle phalanx that is part of a finger [Automatically generated definition]. go-plus.json phalanx media manus|middle phalanx of manual digit|middle manual phalanx|middle phalanx of hand|middle phalanx of finger|hand middle phalanx http://purl.obolibrary.org/obo/UBERON_0003864 GO:0060849 biolink:BiologicalProcess obsolete regulation of transcription involved in lymphatic endothelial cell fate commitment OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060849 UBERON:0003861 biolink:AnatomicalEntity neural arch posterior part of a vertebra that consists of a pair of pedicles and a pair of laminae, and supports seven processes: four articular processes, two transverse processes one spinous process[WP]. ZFA: A neural arch encloses the neural canal and typically meets its partner to form a neural spine. . go-plus.json vertebra neural arch|dorsal arcocentrum|arcus vertebrae|vertebra dorsal arch|arcus vertebrae|arcus vertebrae (vertebralis)|arcus vertebra http://purl.obolibrary.org/obo/UBERON_0003861 UBERON:0003860 biolink:AnatomicalEntity hindlimb mesenchyme Mesenchyme that is part of a developing hindlimb [Automatically generated definition]. go-plus.json mesenchyme of hind limb|mesenchyme of lower extremity|mesenchyme of hindlimb|lower extremity mesenchyme|hind limb mesenchyme|inferior member mesenchyme|mesenchyme of inferior member http://purl.obolibrary.org/obo/UBERON_0003860 CHEBI:131797 biolink:ChemicalSubstance S-(2-carboxy-2-methylbut-3-en-2-yl)glutathione(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131797 chebi_ph7_3 CHEBI:131798 biolink:ChemicalSubstance S-(2-methyl-1-oxobut-3-en-2-yl)glutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131798 chebi_ph7_3 GO:0035892 biolink:BiologicalProcess modulation of platelet aggregation in other organism Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. go-plus.json regulation of platelet aggregation in other organism|modulation by organism of platelet aggregation in other organism http://purl.obolibrary.org/obo/GO_0035892 GO:0035893 biolink:BiologicalProcess negative regulation of platelet aggregation in other organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism. go-plus.json suppression of platelet aggregation in other organism|downregulation of platelet aggregation in other organism|inhibition of platelet aggregation in other organism|down-regulation of platelet aggregation in other organism http://purl.obolibrary.org/obo/GO_0035893 GO:0035894 biolink:BiologicalProcess positive regulation of platelet aggregation in other organism Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism. go-plus.json upregulation of platelet aggregation in other organism|up-regulation of platelet aggregation in other organism http://purl.obolibrary.org/obo/GO_0035894 GO:0035895 biolink:BiologicalProcess modulation of mast cell degranulation in other organism Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. go-plus.json regulation of mast cell degranulation in other organism http://purl.obolibrary.org/obo/GO_0035895 GO:0035896 biolink:BiologicalProcess positive regulation of mast cell degranulation in other organism Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism. go-plus.json upregulation of mast cell degranulation in other organism|up-regulation of mast cell degranulation in other organism http://purl.obolibrary.org/obo/GO_0035896 GO:0035897 biolink:BiologicalProcess obsolete proteolysis in other organism OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0035897 GO:0035898 biolink:BiologicalProcess parathyroid hormone secretion The regulated release of parathyroid hormone into the circulatory system. go-plus.json PTH secretion|parathyrin secretion|parathormone secretion http://purl.obolibrary.org/obo/GO_0035898 GO:0035899 biolink:BiologicalProcess negative regulation of blood coagulation in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot. go-plus.json inhibition of blood coagulation in other organism|negative regulation of blood clotting in other organism|downregulation of blood coagulation in other organism|suppression of blood coagulation in other organism|down-regulation of blood coagulation in other organism http://purl.obolibrary.org/obo/GO_0035899 GO:0035890 biolink:BiologicalProcess exit from host The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json ejection from host http://purl.obolibrary.org/obo/GO_0035890 GO:0035891 biolink:BiologicalProcess exit from host cell The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json host cell exit|ejection from host cell http://purl.obolibrary.org/obo/GO_0035891 GO:0035889 biolink:BiologicalProcess otolith tethering The attachment of a developing otolith to the kinocilia of tether cells in the inner ear. go-plus.json http://purl.obolibrary.org/obo/GO_0035889 PATO:0001873 biolink:OntologyClass cylindrical A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section. go-plus.json tubulate|rod-like|rod-shaped http://purl.obolibrary.org/obo/PATO_0001873 GO:0035881 biolink:BiologicalProcess amacrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. go-plus.json amacrine neuron differentiation http://purl.obolibrary.org/obo/GO_0035881 GO:0035882 biolink:BiologicalProcess defecation rhythm The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated. go-plus.json defecation cycle|defecation behavior|defecation motor program|DMP http://purl.obolibrary.org/obo/GO_0035882 GO:0035883 biolink:BiologicalProcess enteroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. go-plus.json http://purl.obolibrary.org/obo/GO_0035883 GO:0035884 biolink:BiologicalProcess arabinan biosynthetic process The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues. go-plus.json http://purl.obolibrary.org/obo/GO_0035884 GO:0035885 biolink:MolecularActivity exochitinase activity Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain. RHEA:50672|MetaCyc:RXN-12309 go-plus.json http://purl.obolibrary.org/obo/GO_0035885 GO:0035886 biolink:BiologicalProcess vascular associated smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. go-plus.json vascular smooth muscle cell differentiation|VSMC differentiation|vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0035886 GO:0035887 biolink:BiologicalProcess aortic smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta. go-plus.json http://purl.obolibrary.org/obo/GO_0035887 GO:0035888 biolink:MolecularActivity isoguanine deaminase activity Catalysis of the reaction: isoguanine + H2O = xanthine + NH3. go-plus.json 2-oxoadenine deaminase activity|2-hydroxyadenine deaminase activity http://purl.obolibrary.org/obo/GO_0035888 GO:0035880 biolink:BiologicalProcess embryonic nail plate morphogenesis The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits. go-plus.json http://purl.obolibrary.org/obo/GO_0035880 GO:0035878 biolink:BiologicalProcess nail development The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. go-plus.json http://purl.obolibrary.org/obo/GO_0035878 GO:0035879 biolink:BiologicalProcess plasma membrane lactate transport The directed movement of lactate across a plasma membrane. go-plus.json lactate plasma membrane transport http://purl.obolibrary.org/obo/GO_0035879 GO:0035870 biolink:MolecularActivity dITP diphosphatase activity Catalysis of the reaction: dITP + H2O = dIMP + diphosphate. EC:3.6.1.66|KEGG_REACTION:R03531|RHEA:28342|MetaCyc:RXN0-1602|Reactome:R-HSA-2509838 go-plus.json deoxyinosine triphosphate pyrophosphatase activity|dITP pyrophosphatase activity|2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0035870 CHEBI:131780 biolink:ChemicalSubstance 2-hydroxyisobutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131780 chebi_ph7_3 GO:0035871 biolink:BiologicalProcess protein K11-linked deubiquitination A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein. go-plus.json protein K11-linked deubiquitylation|protein K11-linked deubiquitinylation http://purl.obolibrary.org/obo/GO_0035871 GO:0035872 biolink:BiologicalProcess nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process. go-plus.json nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway|NLR signaling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway|nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction|NOD-like receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035872 GO:0035873 biolink:BiologicalProcess lactate transmembrane transport The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. go-plus.json lactate membrane transport http://purl.obolibrary.org/obo/GO_0035873 CHEBI:131783 biolink:ChemicalSubstance indolmycenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_131783 chebi_ph7_3 GO:0035874 biolink:BiologicalProcess cellular response to copper ion starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions. go-plus.json cellular response to copper starvation http://purl.obolibrary.org/obo/GO_0035874 GO:0035875 biolink:BiologicalProcess maintenance of meiotic sister chromatid cohesion, centromeric The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle. go-plus.json maintenance of sister chromatin cohesion at centromere at meiosis I|maintenance of centromeric meiotic sister chromatin cohesion|maintenance of meiotic sister chromatin cohesion at centromere http://purl.obolibrary.org/obo/GO_0035875 GO:0035876 biolink:BiologicalProcess maintenance of meiotic sister chromatid cohesion, arms The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle. go-plus.json maintenance of sister chromatin cohesion along arms at meiosis I|maintenance of meiotic sister chromatin cohesion along arms http://purl.obolibrary.org/obo/GO_0035876 GO:0035877 biolink:MolecularActivity death effector domain binding Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD). go-plus.json DED binding http://purl.obolibrary.org/obo/GO_0035877 GO:0035867 biolink:CellularComponent alphav-beta3 integrin-IGF-1-IGF1R complex A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0035867 GO:0035868 biolink:CellularComponent alphav-beta3 integrin-HMGB1 complex A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein. go-plus.json alphaV-beta3 integrin-HMGB1 complex|alphav-beta3 integrin-high mobility group box 1 complex http://purl.obolibrary.org/obo/GO_0035868 GO:0035869 biolink:CellularComponent ciliary transition zone A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. go-plus.json cilial transition zone|connecting cilium|cilium transition zone http://purl.obolibrary.org/obo/GO_0035869 CHEBI:131759 biolink:ChemicalSubstance CMP-5'-phosphonoformic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131759 GO:0035860 biolink:BiologicalProcess glial cell-derived neurotrophic factor receptor signaling pathway The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands. go-plus.json GDNF receptor signaling pathway|glial cell derived neurotrophic factor receptor signaling pathway|glial cell line-derived neurotrophic factor receptor signalling pathway|glial cell-derived neurotrophic factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035860 GO:0035861 biolink:CellularComponent site of double-strand break A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. go-plus.json DNA damage foci|IRIF|ionizing radiation-induced foci|DNA damage focus|site of DSB http://purl.obolibrary.org/obo/GO_0035861 GO:0035862 biolink:BiologicalProcess dITP metabolic process The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position. go-plus.json 2'-Deoxyinosine-5'-triphosphate metabolic process|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) metabolic process|deoxyinosine 5'-triphosphate metabolic process|dITP metabolism|2'-Deoxyinosine 5'-triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0035862 GO:0035863 biolink:BiologicalProcess dITP catabolic process The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position. go-plus.json 2'-Deoxyinosine-5'-triphosphate catabolic process|dITP catabolism|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) catabolic process|dITP degradation|deoxyinosine 5'-triphosphate catabolic process|dITP breakdown|2'-Deoxyinosine 5'-triphosphate catabolic process http://purl.obolibrary.org/obo/GO_0035863 GO:0035864 biolink:BiologicalProcess response to potassium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. go-plus.json response to potassium|response to K+ ion http://purl.obolibrary.org/obo/GO_0035864 GO:0035865 biolink:BiologicalProcess cellular response to potassium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. go-plus.json cellular response to K+ ion|cellular response to potassium http://purl.obolibrary.org/obo/GO_0035865 GO:0035866 biolink:CellularComponent alphav-beta3 integrin-PKCalpha complex A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha. go-plus.json alphav-beta3 integrin-protein kinase C alpha complex|alphav-beta3 integrin-PKCa complex http://purl.obolibrary.org/obo/GO_0035866 GO:0035856 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035856 CHEBI:131766 biolink:ChemicalSubstance (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131766 chebi_ph7_3 GO:0035857 biolink:BiologicalProcess eosinophil fate specification The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. go-plus.json eosinophil cell fate specification http://purl.obolibrary.org/obo/GO_0035857 CHEBI:131767 biolink:ChemicalSubstance D-erythrulose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131767 chebi_ph7_3 GO:0035858 biolink:BiologicalProcess eosinophil fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json eosinophil cell fate determination http://purl.obolibrary.org/obo/GO_0035858 GO:0035859 biolink:CellularComponent Seh1-associated complex A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p. go-plus.json SEA complex|GATOR complex http://purl.obolibrary.org/obo/GO_0035859 NCBITaxon:118883 biolink:OrganismalEntity Sulfolobaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_118883 CHEBI:61401 biolink:ChemicalSubstance L-alanyl-gamma-D-glutamyl-meso-diaminopimelate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61401 chebi_ph7_3 CHEBI:61402 biolink:ChemicalSubstance ITP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61402 chebi_ph7_3 GO:0035850 biolink:BiologicalProcess epithelial cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0035850 GO:0035851 biolink:MolecularActivity Krueppel-associated box domain binding Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. go-plus.json Krueppel-associated box binding|KRAB domain binding http://purl.obolibrary.org/obo/GO_0035851 GO:0035852 biolink:BiologicalProcess horizontal cell localization Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina. go-plus.json horizontal cell positioning|retinal horizontal cell positioning|horizontal cell localisation|laminar positioning of retinal horizontal cell http://purl.obolibrary.org/obo/GO_0035852 CHEBI:61405 biolink:ChemicalSubstance trans-tetradec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61405 chebi_ph7_3 CHEBI:61406 biolink:ChemicalSubstance trans-dec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61406 chebi_ph7_3 GO:0035853 biolink:BiologicalProcess chromosome passenger complex localization to spindle midzone A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap. go-plus.json CPC localization to spindle midzone|chromosome passenger complex localization to spindle equator|chromosome passenger complex localization to central spindle|CPC complex localization to spindle midzone|chromosomal passenger complex localization to spindle midzone|chromosome passenger complex localisation to spindle midzone http://purl.obolibrary.org/obo/GO_0035853 GO:0035854 biolink:BiologicalProcess eosinophil fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. go-plus.json eosinophil cell fate commitment http://purl.obolibrary.org/obo/GO_0035854 CHEBI:61403 biolink:ChemicalSubstance psicosyllysine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61403 chebi_ph7_3 CHEBI:61404 biolink:ChemicalSubstance dATP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61404 chebi_ph7_3 GO:0035855 biolink:BiologicalProcess megakaryocyte development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. go-plus.json megakaryocyte cell development http://purl.obolibrary.org/obo/GO_0035855 CHEBI:61409 biolink:ChemicalSubstance dihydroxyphenylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61409 CHEBI:61407 biolink:ChemicalSubstance methoxycinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61407 GO:0035845 biolink:BiologicalProcess photoreceptor cell outer segment organization A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials. go-plus.json photoreceptor outer segment organization|photoreceptor cell outer segment organisation http://purl.obolibrary.org/obo/GO_0035845 GO:0035846 biolink:BiologicalProcess oviduct epithelium development The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct. go-plus.json fallopian tube epithelium development http://purl.obolibrary.org/obo/GO_0035846 GO:0035847 biolink:BiologicalProcess uterine epithelium development The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. go-plus.json uterus epithelial development http://purl.obolibrary.org/obo/GO_0035847 CHEBI:131735 biolink:ChemicalSubstance 4-[(2-hydroxyethoxy)carbonyl]benzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_131735 GO:0035848 biolink:BiologicalProcess oviduct morphogenesis The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. go-plus.json fallopian tube morphogenesis http://purl.obolibrary.org/obo/GO_0035848 GO:0035849 biolink:BiologicalProcess nephric duct elongation The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0035849 CHEBI:131737 biolink:ChemicalSubstance androstane ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_131737 CHEBI:131739 biolink:ChemicalSubstance lysophosphatidylcholine (18:1/0:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131739 chebi_ph7_3 CHEBI:36489 biolink:ChemicalSubstance 17beta-estradiol 3-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36489 CHEBI:61413 biolink:ChemicalSubstance oxa fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61413 CHEBI:61410 biolink:ChemicalSubstance oxa fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61410 CHEBI:36487 biolink:ChemicalSubstance 13-(beta-D-glucosyloxy)docosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36487 chebi_ph7_3 CHEBI:36488 biolink:ChemicalSubstance dammarane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36488 chebi_ph7_3 GO:0035840 biolink:CellularComponent old growing cell tip A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures. go-plus.json old growing cell end http://purl.obolibrary.org/obo/GO_0035840 CHEBI:61411 biolink:ChemicalSubstance divinyl ether fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61411 GO:0035841 biolink:CellularComponent new growing cell tip A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth. go-plus.json new cell tip after activation of bipolar cell growth|post-new end take-off new cell tip|post-NETO new cell tip|post-NETO new cell end http://purl.obolibrary.org/obo/GO_0035841 GO:0035842 biolink:CellularComponent old cell tip after activation of bipolar cell growth A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures. go-plus.json post-new end take-off old cell tip|post-NETO old cell end|post-NETO old cell tip http://purl.obolibrary.org/obo/GO_0035842 CHEBI:61417 biolink:ChemicalSubstance TDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61417 chebi_ph7_3 GO:0035843 biolink:CellularComponent endonuclear canal A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0035843 CHEBI:61414 biolink:ChemicalSubstance ferrichromes go-plus.json http://purl.obolibrary.org/obo/CHEBI_61414 GO:0035844 biolink:BiologicalProcess cloaca development The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. go-plus.json cloacal development http://purl.obolibrary.org/obo/GO_0035844 CHEBI:36481 biolink:ChemicalSubstance oleanane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36481 chebi_ph7_3 CHEBI:36482 biolink:ChemicalSubstance hopane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36482 chebi_ph7_3 CHEBI:36480 biolink:ChemicalSubstance bisabolane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36480 chebi_ph7_3 CHEBI:36485 biolink:ChemicalSubstance lupane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36485 chebi_ph7_3 CHEBI:36486 biolink:ChemicalSubstance 13-(beta-D-glucosyloxy)docosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36486 CHEBI:36483 biolink:ChemicalSubstance protostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36483 chebi_ph7_3 CHEBI:36484 biolink:ChemicalSubstance hopan-22-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_36484 chebi_ph7_3 GO:0035834 biolink:BiologicalProcess indole alkaloid metabolic process The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton. go-plus.json indole alkaloid metabolism http://purl.obolibrary.org/obo/GO_0035834 GO:0035835 biolink:BiologicalProcess indole alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton. go-plus.json indole alkaloid synthesis|indole alkaloid formation|indole alkaloid biosynthesis|indole alkaloid anabolism http://purl.obolibrary.org/obo/GO_0035835 CHEBI:131745 biolink:ChemicalSubstance lysophosphatidylethanolamine (0:0/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_131745 GO:0035836 biolink:BiologicalProcess ergot alkaloid metabolic process The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid. go-plus.json ergot alkaloid metabolism http://purl.obolibrary.org/obo/GO_0035836 GO:0035837 biolink:BiologicalProcess ergot alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of an ergot alkaloid. go-plus.json ergot alkaloid biosynthesis|ergot alkaloid anabolism|ergot alkaloid synthesis|ergot alkaloid formation http://purl.obolibrary.org/obo/GO_0035837 CHEBI:131747 biolink:ChemicalSubstance lanostane ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_131747 CHEBI:131748 biolink:ChemicalSubstance ergostane ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_131748 GO:0035838 biolink:CellularComponent growing cell tip The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs. go-plus.json growing cell end http://purl.obolibrary.org/obo/GO_0035838 GO:0035839 biolink:CellularComponent non-growing cell tip A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures. go-plus.json new cell end|non-growing cell end http://purl.obolibrary.org/obo/GO_0035839 CHEBI:36498 biolink:ChemicalSubstance galactosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36498 chebi_ph7_3 GO:0035830 biolink:BiologicalProcess palmatine metabolic process The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants. go-plus.json palmatine metabolism http://purl.obolibrary.org/obo/GO_0035830 GO:0035831 biolink:BiologicalProcess palmatine biosynthetic process The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants. go-plus.json palmatine anabolism|palmatine biosynthesis|palmatine synthesis|palmatine formation http://purl.obolibrary.org/obo/GO_0035831 GO:0035832 biolink:BiologicalProcess berbamunine metabolic process The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid. go-plus.json berbamunine metabolism http://purl.obolibrary.org/obo/GO_0035832 CHEBI:61425 biolink:ChemicalSubstance psicosyllysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61425 GO:0035833 biolink:BiologicalProcess berbamunine biosynthetic process The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid. go-plus.json berbamunine biosynthesis|berbamunine anabolism|berbamunine synthesis|berbamunine formation http://purl.obolibrary.org/obo/GO_0035833 CHEBI:36492 biolink:ChemicalSubstance (+)-isomenthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36492 chebi_ph7_3 CHEBI:36493 biolink:ChemicalSubstance isomenthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36493 CHEBI:61429 biolink:ChemicalSubstance dGTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61429 chebi_ph7_3 CHEBI:36491 biolink:ChemicalSubstance 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36491 CHEBI:36496 biolink:ChemicalSubstance (-)-isomenthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_36496 chebi_ph7_3 GO:0045196 biolink:BiologicalProcess establishment or maintenance of neuroblast polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. go-plus.json establishment and/or maintenance of neuroblast cell polarity http://purl.obolibrary.org/obo/GO_0045196 GO:0070152 biolink:BiologicalProcess mitochondrial isoleucyl-tRNA aminoacylation The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070152 GO:0070153 biolink:BiologicalProcess mitochondrial leucyl-tRNA aminoacylation The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070153 GO:0045197 biolink:BiologicalProcess establishment or maintenance of epithelial cell apical/basal polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0045197 GO:0045194 biolink:BiologicalProcess obsolete oxidized low-density lipoprotein catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins. go-plus.json Ox-LDL catabolism|oxidized low-density lipoprotein degradation|Ox-LDL catabolic process|oxidized low-density lipoprotein breakdown|oxidized low-density lipoprotein catabolic process|oxidized low-density lipoprotein catabolism http://purl.obolibrary.org/obo/GO_0045194 GO:0070150 biolink:BiologicalProcess mitochondrial glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070150 GO:0070151 biolink:BiologicalProcess mitochondrial histidyl-tRNA aminoacylation The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070151 GO:0045195 biolink:BiologicalProcess obsolete gallstone formation OBSOLETE. The formation of gallstones, hard, crystal-like accretions of cholesterol and bile pigments which develop when bile contains too much cholesterol and not enough bile. go-plus.json gallstone formation http://purl.obolibrary.org/obo/GO_0045195 GO:0045192 biolink:BiologicalProcess obsolete low-density lipoprotein catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats. go-plus.json low-density lipoprotein degradation|LDL catabolism|low-density lipoprotein catabolism|low-density lipoprotein breakdown|low-density lipoprotein catabolic process|LDL catabolic process http://purl.obolibrary.org/obo/GO_0045192 GO:0045193 biolink:BiologicalProcess obsolete acetylated low-density lipoprotein catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins. go-plus.json acetylated low-density lipoprotein degradation|acetylated low-density lipoprotein breakdown|acetylated low-density lipoprotein catabolic process|Ac-LDL catabolic process|Ac-LDL catabolism|acetylated low-density lipoprotein catabolism http://purl.obolibrary.org/obo/GO_0045193 GO:0045190 biolink:BiologicalProcess isotype switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. Wikipedia:Immunoglobulin_class_switching go-plus.json class switch recombination|isotype switch recombination|class switching http://purl.obolibrary.org/obo/GO_0045190 GO:0045191 biolink:BiologicalProcess regulation of isotype switching Any process that modulates the frequency, rate or extent of isotype switching. go-plus.json regulation of class switching|regulation of class switch recombination|regulation of isotype switch recombination http://purl.obolibrary.org/obo/GO_0045191 GO:1901688 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901688 GO:1901689 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901689 GO:1901686 biolink:BiologicalProcess glutathione derivative catabolic process The chemical reactions and pathways resulting in the breakdown of glutathione derivative. go-plus.json glutathione derivative breakdown|glutathione derivative catabolism|glutathione derivative degradation http://purl.obolibrary.org/obo/GO_1901686 GO:1901687 biolink:BiologicalProcess glutathione derivative biosynthetic process The chemical reactions and pathways resulting in the formation of glutathione derivative. go-plus.json glutathione derivative biosynthesis|glutathione derivative anabolism|glutathione derivative synthesis|glutathione derivative formation http://purl.obolibrary.org/obo/GO_1901687 GO:1901684 biolink:BiologicalProcess arsenate ion transmembrane transport The process in which arsenate is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1901684 GO:1901685 biolink:BiologicalProcess glutathione derivative metabolic process The chemical reactions and pathways involving glutathione derivative. go-plus.json glutathione derivative metabolism http://purl.obolibrary.org/obo/GO_1901685 GO:1901682 biolink:MolecularActivity sulfur compound transmembrane transporter activity Enables the transfer of a sulfur compound from one side of a membrane to the other. go-plus.json sulfur molecular entity transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901682 GO:0045198 biolink:BiologicalProcess establishment of epithelial cell apical/basal polarity The specification and formation of the apicobasal polarity of an epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0045198 GO:1901683 biolink:MolecularActivity arsenate ion transmembrane transporter activity Enables the transfer of an arsenate ion from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901683 GO:0045199 biolink:BiologicalProcess maintenance of epithelial cell apical/basal polarity The maintenance of the apicobasal polarity of an epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0045199 GO:1901691 biolink:MolecularActivity proton binding Binding to proton. go-plus.json hydrogen ion binding http://purl.obolibrary.org/obo/GO_1901691 GO:1901692 biolink:BiologicalProcess regulation of compound eye retinal cell apoptotic process Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process. go-plus.json http://purl.obolibrary.org/obo/GO_1901692 GO:1901690 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901690 GO:0070158 biolink:BiologicalProcess mitochondrial seryl-tRNA aminoacylation The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070158 GO:0070159 biolink:BiologicalProcess mitochondrial threonyl-tRNA aminoacylation The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070159 GO:0070156 biolink:BiologicalProcess mitochondrial phenylalanyl-tRNA aminoacylation The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070156 GO:0070157 biolink:BiologicalProcess mitochondrial prolyl-tRNA aminoacylation The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070157 GO:0070154 biolink:BiologicalProcess mitochondrial lysyl-tRNA aminoacylation The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070154 GO:0070155 biolink:BiologicalProcess mitochondrial methionyl-tRNA aminoacylation The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070155 GO:0070141 biolink:BiologicalProcess response to UV-A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. go-plus.json response to UVA light stimulus|response to UV-A light stimulus|response to UVA radiation stimulus|response to UV-A radiation stimulus http://purl.obolibrary.org/obo/GO_0070141 GO:0070142 biolink:BiologicalProcess synaptic vesicle budding Evagination of a membrane to form a synaptic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0070142 GO:0070140 biolink:MolecularActivity SUMO-specific isopeptidase activity Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated. go-plus.json http://purl.obolibrary.org/obo/GO_0070140 GO:1901699 biolink:BiologicalProcess cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. go-plus.json cellular response to nitrogen molecular entity http://purl.obolibrary.org/obo/GO_1901699 GO:1901697 biolink:BiologicalProcess olivetolic acid biosynthetic process The chemical reactions and pathways resulting in the formation of olivetolic acid. go-plus.json olivetolic acid anabolism|olivetolic acid synthesis|olivetolic acid biosynthesis|olivetolic acid formation http://purl.obolibrary.org/obo/GO_1901697 GO:1901698 biolink:BiologicalProcess response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. go-plus.json response to nitrogen molecular entity http://purl.obolibrary.org/obo/GO_1901698 GO:1901695 biolink:BiologicalProcess tyramine biosynthetic process The chemical reactions and pathways resulting in the formation of tyramine. go-plus.json tyramine biosynthesis|tyramine anabolism|tyramine synthesis|tyramine formation http://purl.obolibrary.org/obo/GO_1901695 GO:1901696 biolink:BiologicalProcess cannabinoid biosynthetic process The chemical reactions and pathways resulting in the formation of cannabinoid. go-plus.json cannabinoid biosynthesis|cannabinoid anabolism|cannabinoid synthesis|cannabinoid formation http://purl.obolibrary.org/obo/GO_1901696 GO:1901693 biolink:BiologicalProcess negative regulation of compound eye retinal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process. go-plus.json down-regulation of compound eye retinal cell apoptotic process|inhibition of compound eye retinal cell apoptotic process|down regulation of compound eye retinal cell apoptotic process|downregulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1901693 GO:1901694 biolink:BiologicalProcess positive regulation of compound eye retinal cell apoptotic process Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process. go-plus.json induction of compound eye retinal cell programmed cell death|up-regulation of compound eye retinal cell apoptotic process|upregulation of compound eye retinal cell apoptotic process|up regulation of compound eye retinal cell apoptotic process|activation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1901694 GO:0070149 biolink:BiologicalProcess mitochondrial glutamyl-tRNA aminoacylation The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070149 GO:0070147 biolink:BiologicalProcess mitochondrial cysteinyl-tRNA aminoacylation The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070147 GO:0070148 biolink:BiologicalProcess mitochondrial glutaminyl-tRNA aminoacylation The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070148 GO:0070145 biolink:BiologicalProcess mitochondrial asparaginyl-tRNA aminoacylation The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070145 GO:0070146 biolink:BiologicalProcess mitochondrial aspartyl-tRNA aminoacylation The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070146 GO:0070143 biolink:BiologicalProcess mitochondrial alanyl-tRNA aminoacylation The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070143 GO:0070144 biolink:BiologicalProcess mitochondrial arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070144 GO:0070174 biolink:BiologicalProcess negative regulation of enamel mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. go-plus.json http://purl.obolibrary.org/obo/GO_0070174 GO:0070175 biolink:BiologicalProcess positive regulation of enamel mineralization Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. go-plus.json http://purl.obolibrary.org/obo/GO_0070175 GO:0070172 biolink:BiologicalProcess positive regulation of tooth mineralization Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. go-plus.json http://purl.obolibrary.org/obo/GO_0070172 GO:0070173 biolink:BiologicalProcess regulation of enamel mineralization Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. go-plus.json http://purl.obolibrary.org/obo/GO_0070173 GO:0070170 biolink:BiologicalProcess regulation of tooth mineralization Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. go-plus.json http://purl.obolibrary.org/obo/GO_0070170 GO:0070171 biolink:BiologicalProcess negative regulation of tooth mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. go-plus.json http://purl.obolibrary.org/obo/GO_0070171 GO:0070178 biolink:BiologicalProcess D-serine metabolic process The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. go-plus.json D-serine metabolism http://purl.obolibrary.org/obo/GO_0070178 GO:0070179 biolink:BiologicalProcess D-serine biosynthetic process The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine. go-plus.json D-serine biosynthesis|D-serine anabolism|D-serine synthesis|D-serine formation http://purl.obolibrary.org/obo/GO_0070179 GO:0070176 biolink:CellularComponent DRM complex A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification. go-plus.json DP/Rb/MuvB http://purl.obolibrary.org/obo/GO_0070176 GO:0070177 biolink:BiologicalProcess contractile vacuole discharge The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0070177 GO:0070163 biolink:BiologicalProcess regulation of adiponectin secretion Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0070163 GO:0070164 biolink:BiologicalProcess negative regulation of adiponectin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell. go-plus.json down regulation of adiponectin secretion|downregulation of adiponectin secretion|down-regulation of adiponectin secretion|inhibition of adiponectin secretion http://purl.obolibrary.org/obo/GO_0070164 GO:0070161 biolink:CellularComponent anchoring junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. go-plus.json anchoring cell junction http://purl.obolibrary.org/obo/GO_0070161 GO:0070162 biolink:BiologicalProcess adiponectin secretion The regulated release of adiponectin, a protein hormone, by adipose tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0070162 GO:0070160 biolink:CellularComponent tight junction A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. Wikipedia:Tight_junction go-plus.json occluding cell junction|occluding junction http://purl.obolibrary.org/obo/GO_0070160 GO:0070169 biolink:BiologicalProcess positive regulation of biomineral tissue development Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0070169 GO:0070167 biolink:BiologicalProcess regulation of biomineral tissue development Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0070167 GO:0070168 biolink:BiologicalProcess negative regulation of biomineral tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0070168 GO:0070165 biolink:BiologicalProcess positive regulation of adiponectin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell. go-plus.json upregulation of adiponectin secretion|up regulation of adiponectin secretion|activation of adiponectin secretion|stimulation of adiponectin secretion|up-regulation of adiponectin secretion http://purl.obolibrary.org/obo/GO_0070165 GO:0070166 biolink:BiologicalProcess enamel mineralization The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel. go-plus.json enamel formation http://purl.obolibrary.org/obo/GO_0070166 GO:0070196 biolink:BiologicalProcess eukaryotic translation initiation factor 3 complex assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex. go-plus.json eIF-3 assembly|eIF3 assembly http://purl.obolibrary.org/obo/GO_0070196 GO:0070197 biolink:BiologicalProcess meiotic attachment of telomere to nuclear envelope The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation. go-plus.json attachment of telomeric chromatin to nuclear envelope|attachment of telomeres to nuclear envelope http://purl.obolibrary.org/obo/GO_0070197 GO:0070194 biolink:BiologicalProcess synaptonemal complex disassembly The controlled breakdown of a synaptonemal complex. go-plus.json http://purl.obolibrary.org/obo/GO_0070194 GO:0070195 biolink:CellularComponent growth hormone receptor complex A receptor complex that consists of two identical subunits and binds growth hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0070195 GO:0070192 biolink:BiologicalProcess chromosome organization involved in meiotic cell cycle A process of chromosome organization that is involved in a meiotic cell cycle. go-plus.json chromosome organisation involved in meiosis|meiotic chromosome organization http://purl.obolibrary.org/obo/GO_0070192 GO:0070193 biolink:BiologicalProcess synaptonemal complex organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis. go-plus.json synaptonemal complex organisation http://purl.obolibrary.org/obo/GO_0070193 GO:0070190 biolink:MolecularActivity obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate. go-plus.json inositol hexakisphosphate 1-kinase or 3-kinase activity http://purl.obolibrary.org/obo/GO_0070190 GO:0070191 biolink:MolecularActivity methionine-R-sulfoxide reductase activity Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin. go-plus.json http://purl.obolibrary.org/obo/GO_0070191 NCBITaxon:33213 biolink:OrganismalEntity Bilateria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_33213 GO:0070198 biolink:BiologicalProcess protein localization to chromosome, telomeric region Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome. go-plus.json protein localisation to chromosome, telomeric region|protein localization to telomere http://purl.obolibrary.org/obo/GO_0070198 GO:0070199 biolink:BiologicalProcess establishment of protein localization to chromosome The directed movement of a protein to a specific location on a chromosome. go-plus.json establishment of protein localisation to chromosome http://purl.obolibrary.org/obo/GO_0070199 GO:0070185 biolink:BiologicalProcess mitochondrial valyl-tRNA aminoacylation The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070185 GO:0070186 biolink:MolecularActivity growth hormone activity The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth. go-plus.json pituitary growth hormone activity|GH activity|placental growth hormone activity http://purl.obolibrary.org/obo/GO_0070186 GO:0070183 biolink:BiologicalProcess mitochondrial tryptophanyl-tRNA aminoacylation The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070183 GO:0070184 biolink:BiologicalProcess mitochondrial tyrosyl-tRNA aminoacylation The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070184 GO:0070181 biolink:MolecularActivity small ribosomal subunit rRNA binding Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA. go-plus.json SSU rRNA binding|18S rRNA binding http://purl.obolibrary.org/obo/GO_0070181 GO:0070182 biolink:MolecularActivity DNA polymerase binding Binding to a DNA polymerase. go-plus.json http://purl.obolibrary.org/obo/GO_0070182 GO:0070180 biolink:MolecularActivity large ribosomal subunit rRNA binding Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA. go-plus.json LSU rRNA binding|25S rRNA binding http://purl.obolibrary.org/obo/GO_0070180 OBO:GOCHE_76668 biolink:OntologyClass substance with EC 2.7.* (P-containing group transferase) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76668 3_STAR NCBITaxon:33208 biolink:OrganismalEntity Metazoa go-plus.json multicellular animals|animals|Animalia|metazoans http://purl.obolibrary.org/obo/NCBITaxon_33208 GO:0070189 biolink:BiologicalProcess kynurenine metabolic process The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. go-plus.json kynurenine metabolism http://purl.obolibrary.org/obo/GO_0070189 GO:0070187 biolink:CellularComponent shelterin complex A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1. go-plus.json Pot1-Tpz1 complex|Pot1 complex|telosome http://purl.obolibrary.org/obo/GO_0070187 GO:0070188 biolink:CellularComponent obsolete Stn1-Ten1 complex OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present. go-plus.json http://purl.obolibrary.org/obo/GO_0070188 CHEBI:141140 biolink:ChemicalSubstance medium-chain fatty acyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141140 chebi_ph7_3 NCBITaxon:261009 biolink:OrganismalEntity Amborellales go-plus.json ANA grade angiosperms|ANITA grade angiosperms http://purl.obolibrary.org/obo/NCBITaxon_261009 OBA:VT2000000 biolink:OntologyClass arterial blood pressure trait The pressure of a arterial blood. go-plus.json pressure of arterial blood http://purl.obolibrary.org/obo/OBA_VT2000000 CHEBI:141131 biolink:ChemicalSubstance acyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141131 chebi_ph7_3 GO:0035793 biolink:BiologicalProcess positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands. go-plus.json positive regulation of metanephric mesenchymal cell migration by PDGF receptor-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway|positive regulation of metanephric mesenchymal cell migration by PDGFR-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by betaPDGF receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035793 GO:0035794 biolink:BiologicalProcess positive regulation of mitochondrial membrane permeability Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. go-plus.json mitochondrial membrane permeability transition|mitochondrial membrane permeabilization|MPT|positive regulation of transport across mitochondrial membrane|mitochondrial permeability transition http://purl.obolibrary.org/obo/GO_0035794 GO:0035795 biolink:BiologicalProcess negative regulation of mitochondrial membrane permeability Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. go-plus.json mitochondrial membrane impermeabilization|negative regulation of transport across mitochondrial membrane|mitochondrial membrane impermeability http://purl.obolibrary.org/obo/GO_0035795 GO:0035796 biolink:CellularComponent ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP. go-plus.json energy coupling factor (ECF)-type ABC transporter|energy-coupling factor transporter|ATP-binding cassette (ABC) transporter complex, ECF-type http://purl.obolibrary.org/obo/GO_0035796 GO:0035797 biolink:MolecularActivity tellurite methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride). go-plus.json SAM-dependent tellurite methyltransferase activity|tellurite methylase activity|S-adenosyl-L-methionine-dependent tellurite methyltransferase activity http://purl.obolibrary.org/obo/GO_0035797 GO:0035798 biolink:MolecularActivity 2-alkenal reductase (NADP+) activity Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+. go-plus.json NADPH:2-alkenal alpha,beta-hydrogenase activity http://purl.obolibrary.org/obo/GO_0035798 GO:0035799 biolink:BiologicalProcess ureter maturation A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. go-plus.json http://purl.obolibrary.org/obo/GO_0035799 GO:0035790 biolink:BiologicalProcess platelet-derived growth factor receptor-alpha signaling pathway A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json platelet-derived growth factor receptor-alpha signalling pathway|PDGF receptor-alpha signaling pathway|PDGFR-alpha signaling pathway|alphaPDGF receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035790 GO:0035791 biolink:BiologicalProcess platelet-derived growth factor receptor-beta signaling pathway A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json PDGFR-beta signaling pathway|betaPDGF receptor signaling pathway|PDGF receptor-beta signaling pathway|platelet-derived growth factor receptor-beta signalling pathway http://purl.obolibrary.org/obo/GO_0035791 GO:0035792 biolink:CellularComponent host cell postsynaptic membrane A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane. go-plus.json other organism postsynaptic membrane|other organism post-synaptic membrane http://purl.obolibrary.org/obo/GO_0035792 GO:1901608 biolink:BiologicalProcess regulation of vesicle transport along microtubule Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. go-plus.json regulation of microtubule-based vesicle localization http://purl.obolibrary.org/obo/GO_1901608 GO:1901609 biolink:BiologicalProcess negative regulation of vesicle transport along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. go-plus.json inhibition of vesicle transport along microtubule|down-regulation of microtubule-based vesicle localization|negative regulation of microtubule-based vesicle localization|downregulation of microtubule-based vesicle localization|down regulation of vesicle transport along microtubule|down regulation of microtubule-based vesicle localization|downregulation of vesicle transport along microtubule|inhibition of microtubule-based vesicle localization|down-regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901609 GO:1901606 biolink:BiologicalProcess alpha-amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. go-plus.json alpha-amino acid catabolism|alpha-amino acid degradation|alpha-amino acid breakdown http://purl.obolibrary.org/obo/GO_1901606 GO:1901607 biolink:BiologicalProcess alpha-amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of an alpha-amino acid. go-plus.json alpha-amino acid anabolism|alpha-amino acid synthesis|alpha-amino acid formation|alpha-amino acid biosynthesis http://purl.obolibrary.org/obo/GO_1901607 GO:1901604 biolink:MolecularActivity dethiobiotin transmembrane transporter activity Enables the transfer of dethiobiotin from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901604 GO:1901605 biolink:BiologicalProcess alpha-amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid. go-plus.json alpha-amino acid metabolism http://purl.obolibrary.org/obo/GO_1901605 GO:1901602 biolink:MolecularActivity dethiobiotin binding Binding to dethiobiotin. go-plus.json http://purl.obolibrary.org/obo/GO_1901602 GO:1901603 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901603 GO:0045116 biolink:BiologicalProcess protein neddylation Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein. go-plus.json RUB1-protein conjugation http://purl.obolibrary.org/obo/GO_0045116 GO:1901600 biolink:BiologicalProcess strigolactone metabolic process The chemical reactions and pathways involving strigolactone. go-plus.json strigolactone metabolism http://purl.obolibrary.org/obo/GO_1901600 CHEBI:85360 biolink:ChemicalSubstance L-dihydroanticapsin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85360 CHEBI:61393 biolink:ChemicalSubstance fructosyllysine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61393 chebi_ph7_3 GO:0045117 biolink:BiologicalProcess azole transmembrane transport The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane. go-plus.json azole transport http://purl.obolibrary.org/obo/GO_0045117 GO:1901601 biolink:BiologicalProcess strigolactone biosynthetic process The chemical reactions and pathways resulting in the formation of strigolactone. go-plus.json strigolactone anabolism|strigolactone synthesis|strigolactone formation|strigolactone biosynthesis http://purl.obolibrary.org/obo/GO_1901601 GO:0045114 biolink:BiologicalProcess beta 2 integrin biosynthetic process The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit. go-plus.json beta 2 integrin biosynthesis|beta 2 integrin anabolism|beta 2 integrin synthesis|beta 2 integrin formation http://purl.obolibrary.org/obo/GO_0045114 GO:0045115 biolink:BiologicalProcess regulation of beta 2 integrin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins. go-plus.json regulation of beta 2 integrin anabolism|regulation of beta 2 integrin synthesis|regulation of beta 2 integrin formation|regulation of beta 2 integrin biosynthesis http://purl.obolibrary.org/obo/GO_0045115 CHEBI:61392 biolink:ChemicalSubstance fructoselysine 6-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61392 chebi_ph7_3 GO:0045112 biolink:BiologicalProcess integrin biosynthetic process The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules. go-plus.json integrin biosynthesis|integrin anabolism|integrin synthesis|integrin formation http://purl.obolibrary.org/obo/GO_0045112 GO:0045113 biolink:BiologicalProcess regulation of integrin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. go-plus.json regulation of integrin synthesis|regulation of integrin formation|regulation of integrin biosynthesis|regulation of integrin anabolism http://purl.obolibrary.org/obo/GO_0045113 GO:0045110 biolink:BiologicalProcess intermediate filament bundle assembly The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. go-plus.json tonofilament assembly http://purl.obolibrary.org/obo/GO_0045110 CHEBI:61395 biolink:ChemicalSubstance L-alanyl-D-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61395 chebi_ph7_3 CHEBI:85366 biolink:ChemicalSubstance 3-hydroxy-2,4-dioxopentyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85366 CHEBI:85367 biolink:ChemicalSubstance 2-epi-5-epi-valiolone 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85367 CHEBI:61396 biolink:ChemicalSubstance L-alanyl-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61396 chebi_ph7_3 GO:0045111 biolink:CellularComponent intermediate filament cytoskeleton Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0045111 CHEBI:85368 biolink:ChemicalSubstance dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_85368 GO:0060750 biolink:BiologicalProcess epithelial cell proliferation involved in mammary gland duct elongation The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth. go-plus.json http://purl.obolibrary.org/obo/GO_0060750 CHEBI:85369 biolink:ChemicalSubstance dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_85369 GO:0060751 biolink:BiologicalProcess branch elongation involved in mammary gland duct branching The developmental growth process in which a branch of a mammary gland duct elongates. go-plus.json mammary gland duct branch elongation http://purl.obolibrary.org/obo/GO_0060751 GO:0060752 biolink:BiologicalProcess intestinal phytosterol absorption Any process in which phytosterols are taken up from the contents of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0060752 GO:0060753 biolink:BiologicalProcess regulation of mast cell chemotaxis Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0060753 GO:0060754 biolink:BiologicalProcess positive regulation of mast cell chemotaxis Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0060754 GO:0060755 biolink:BiologicalProcess negative regulation of mast cell chemotaxis Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0060755 GO:0045118 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045118 GO:0045119 biolink:MolecularActivity azole:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances. go-plus.json azole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0045119 GO:0060756 biolink:BiologicalProcess foraging behavior Behavior by which an organism locates food. go-plus.json http://purl.obolibrary.org/obo/GO_0060756 GO:0060757 biolink:BiologicalProcess adult foraging behavior Behavior by which an adult locates food. go-plus.json http://purl.obolibrary.org/obo/GO_0060757 GO:0060758 biolink:BiologicalProcess foraging behavior by probing substrate Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food. go-plus.json http://purl.obolibrary.org/obo/GO_0060758 GO:0060759 biolink:BiologicalProcess regulation of response to cytokine stimulus Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0060759 GO:1901619 biolink:BiologicalProcess obsolete tRNA methylation in response to nitrogen starvation OBSOLETE. The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule as a result of deprivation of nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_1901619 GO:0045120 biolink:CellularComponent pronucleus The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents. Wikipedia:Pronucleus go-plus.json http://purl.obolibrary.org/obo/GO_0045120 UBERON:0013240 biolink:AnatomicalEntity future glans clitoris A future glans that is part of a female genital tubercle. go-plus.json glans of female genital tubercle http://purl.obolibrary.org/obo/UBERON_0013240 GO:1901617 biolink:BiologicalProcess organic hydroxy compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic hydroxy compound. go-plus.json organic hydroxy compound anabolism|organic hydroxy compound synthesis|organic hydroxy compound formation|organic hydroxy compound biosynthesis http://purl.obolibrary.org/obo/GO_1901617 GO:1901618 biolink:MolecularActivity organic hydroxy compound transmembrane transporter activity Enables the transfer of organic hydroxy compound from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901618 UBERON:0013241 biolink:AnatomicalEntity embryonic urethral groove The precursor of the urethra go-plus.json sulcus urethralis primarius|urethral groove|urethral sulcus http://purl.obolibrary.org/obo/UBERON_0013241 GO:1901615 biolink:BiologicalProcess organic hydroxy compound metabolic process The chemical reactions and pathways involving organic hydroxy compound. go-plus.json organic hydroxy compound metabolism http://purl.obolibrary.org/obo/GO_1901615 GO:1901616 biolink:BiologicalProcess organic hydroxy compound catabolic process The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound. go-plus.json organic hydroxy compound degradation|organic hydroxy compound breakdown|organic hydroxy compound catabolism http://purl.obolibrary.org/obo/GO_1901616 GO:1901613 biolink:BiologicalProcess negative regulation of terminal button organization Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization. go-plus.json downregulation of terminal bouton organization|downregulation of terminal button organisation|down regulation of bouton organization|down regulation of terminal bouton organization|down regulation of terminal button organisation|downregulation of synaptic bouton organization|inhibition of terminal button organisation|downregulation of bouton organization|inhibition of terminal bouton organization|downregulation of terminal button organization|down regulation of presynaptic bouton organization|down regulation of synaptic bouton organization|down regulation of terminal button organization|inhibition of synaptic bouton organization|downregulation of presynaptic bouton organization|inhibition of terminal button organization|negative regulation of bouton organization|down-regulation of bouton organization|negative regulation of presynaptic bouton organization|down-regulation of presynaptic bouton organization|inhibition of bouton organization|down-regulation of terminal bouton organization|down-regulation of terminal button organisation|negative regulation of terminal bouton organization|negative regulation of terminal button organisation|negative regulation of synaptic bouton organization|inhibition of presynaptic bouton organization|down-regulation of synaptic bouton organization|down-regulation of terminal button organization http://purl.obolibrary.org/obo/GO_1901613 GO:1901614 biolink:BiologicalProcess positive regulation of terminal button organization Any process that activates or increases the frequency, rate or extent of terminal button organization. go-plus.json positive regulation of synaptic bouton organization|up regulation of synaptic bouton organization|up regulation of terminal button organization|upregulation of presynaptic bouton organization|upregulation of terminal bouton organization|upregulation of terminal button organisation|up regulation of bouton organization|positive regulation of bouton organization|activation of bouton organization|upregulation of synaptic bouton organization|upregulation of terminal button organization|up regulation of presynaptic bouton organization|up-regulation of terminal button organisation|up-regulation of terminal bouton organization|activation of presynaptic bouton organization|positive regulation of presynaptic bouton organization|activation of terminal button organisation|activation of terminal bouton organization|up-regulation of synaptic bouton organization|activation of synaptic bouton organization|up-regulation of bouton organization|up-regulation of terminal button organization|activation of terminal button organization|positive regulation of terminal button organisation|positive regulation of terminal bouton organization|up-regulation of presynaptic bouton organization|up regulation of terminal bouton organization|up regulation of terminal button organisation|upregulation of bouton organization http://purl.obolibrary.org/obo/GO_1901614 GO:1901611 biolink:MolecularActivity phosphatidylglycerol binding Binding to phosphatidylglycerol. go-plus.json http://purl.obolibrary.org/obo/GO_1901611 GO:0045127 biolink:MolecularActivity N-acetylglucosamine kinase activity Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+). Reactome:R-HSA-6803771|EC:2.7.1.59|KEGG_REACTION:R01201|RHEA:17417|MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN go-plus.json GlcNAc kinase activity|acetylglucosamine kinase (phosphorylating)|ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity|ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity|2-acetylamino-2-deoxy-D-glucose kinase activity|acetylaminodeoxyglucokinase activity http://purl.obolibrary.org/obo/GO_0045127 UBERON:0013247 biolink:AnatomicalEntity male paramesonephric duct A epithelial tube that develops from a Mullerian duct in a male. Later degenerates. go-plus.json degenerating mesonephric portion of male paramesonephric duct http://purl.obolibrary.org/obo/UBERON_0013247 GO:0045128 biolink:BiologicalProcess negative regulation of reciprocal meiotic recombination Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json down regulation of meiotic recombination|downregulation of meiotic recombination|suppression of meiotic recombination|down-regulation of meiotic recombination|inhibition of meiotic recombination http://purl.obolibrary.org/obo/GO_0045128 GO:1901612 biolink:MolecularActivity cardiolipin binding Binding to cardiolipin. go-plus.json http://purl.obolibrary.org/obo/GO_1901612 CHEBI:85350 biolink:ChemicalSubstance CDP-1-palmitoyl-2-arachidonoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85350 chebi_ph7_3 GO:0045125 biolink:MolecularActivity bioactive lipid receptor activity Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes. go-plus.json http://purl.obolibrary.org/obo/GO_0045125 CHEBI:85351 biolink:ChemicalSubstance CDP-1,2-diarachidonoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85351 chebi_ph7_3 GO:1901610 biolink:BiologicalProcess positive regulation of vesicle transport along microtubule Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. go-plus.json up regulation of vesicle transport along microtubule|activation of vesicle transport along microtubule|up-regulation of microtubule-based vesicle localization|activation of microtubule-based vesicle localization|up-regulation of vesicle transport along microtubule|positive regulation of microtubule-based vesicle localization|up regulation of microtubule-based vesicle localization|upregulation of vesicle transport along microtubule|upregulation of microtubule-based vesicle localization http://purl.obolibrary.org/obo/GO_1901610 GO:0045126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045126 CHEBI:85352 biolink:ChemicalSubstance CDP-1-stearoyl-2-linoleoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85352 chebi_ph7_3 GO:0045123 biolink:BiologicalProcess cellular extravasation The migration of a leukocyte from the blood vessels into the surrounding tissue. Wikipedia:Leukocyte_extravasation go-plus.json leucocyte cellular extravasation|transendothelial leukocyte migration|immune cell cellular extravasation|leukocyte cellular extravasation http://purl.obolibrary.org/obo/GO_0045123 CHEBI:85353 biolink:ChemicalSubstance CDP-1-stearoyl-2-oleoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85353 chebi_ph7_3 GO:0045124 biolink:BiologicalProcess regulation of bone resorption Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). go-plus.json http://purl.obolibrary.org/obo/GO_0045124 CHEBI:85354 biolink:ChemicalSubstance CDP-1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85354 chebi_ph7_3 GO:0045121 biolink:CellularComponent membrane raft Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. Wikipedia:Lipid_raft go-plus.json GEM domain|glycolipid-enriched membrane domain|lipid raft http://purl.obolibrary.org/obo/GO_0045121 CHEBI:85355 biolink:ChemicalSubstance CDP-1,2-dilinoleoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85355 chebi_ph7_3 GO:0045122 biolink:BiologicalProcess aflatoxin biosynthetic process The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. go-plus.json aflatoxin synthesis|aflatoxin formation|aflatoxin biosynthesis|aflatoxin anabolism http://purl.obolibrary.org/obo/GO_0045122 CHEBI:85356 biolink:ChemicalSubstance CDP-1,2-dioleoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85356 chebi_ph7_3 CHEBI:85357 biolink:ChemicalSubstance 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85357 GO:0060740 biolink:BiologicalProcess prostate gland epithelium morphogenesis The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. go-plus.json http://purl.obolibrary.org/obo/GO_0060740 GO:0060741 biolink:BiologicalProcess prostate gland stromal morphogenesis The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060741 UBERON:0013239 biolink:AnatomicalEntity future glans penis A future glans that is part of a male genital tubercle. go-plus.json glans of male genital tubercle http://purl.obolibrary.org/obo/UBERON_0013239 GO:0060742 biolink:BiologicalProcess epithelial cell differentiation involved in prostate gland development The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060742 GO:0060743 biolink:BiologicalProcess epithelial cell maturation involved in prostate gland development The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. go-plus.json prostate gland epithelial cell development http://purl.obolibrary.org/obo/GO_0060743 GO:0045129 biolink:MolecularActivity NAD-independent histone deacetylase activity Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone. go-plus.json AcuC http://purl.obolibrary.org/obo/GO_0045129 GO:0060744 biolink:BiologicalProcess mammary gland branching involved in thelarche The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. go-plus.json mammary gland branching involved in puberty http://purl.obolibrary.org/obo/GO_0060744 GO:0060745 biolink:BiologicalProcess mammary gland branching involved in pregnancy The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy. go-plus.json http://purl.obolibrary.org/obo/GO_0060745 GO:0060746 biolink:BiologicalProcess parental behavior A reproductive behavior in which a parent cares for and rears offspring. go-plus.json http://purl.obolibrary.org/obo/GO_0060746 GO:0060747 biolink:BiologicalProcess oral incubation A parental behavior in which fertilized eggs are taken into the mouth and held until hatching. go-plus.json http://purl.obolibrary.org/obo/GO_0060747 GO:0060748 biolink:BiologicalProcess tertiary branching involved in mammary gland duct morphogenesis The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy. go-plus.json http://purl.obolibrary.org/obo/GO_0060748 GO:0060749 biolink:BiologicalProcess mammary gland alveolus development The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. go-plus.json http://purl.obolibrary.org/obo/GO_0060749 GO:0045130 biolink:MolecularActivity keratan sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate. Reactome:R-HSA-2046175|MetaCyc:KERATAN-SULFOTRANSFERASE-RXN|EC:2.8.2.21 go-plus.json 3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity|3'-phosphoadenylylsulfate:keratan sulfotransferase activity|keratan sulphotransferase activity|keratan sulfate Gal-6-sulfotransferase activity|keratan sulfate sulfotransferase activity|3'-phosphoadenylyl keratan sulfotransferase activity http://purl.obolibrary.org/obo/GO_0045130 GO:0045131 biolink:MolecularActivity pre-mRNA branch point binding Binding to a pre-mRNA branch point sequence, located upstream of the 3' splice site. go-plus.json http://purl.obolibrary.org/obo/GO_0045131 GO:1901628 biolink:BiologicalProcess positive regulation of postsynaptic membrane organization Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization. go-plus.json upregulation of postsynaptic membrane organization|up-regulation of postsynaptic membrane organisation|activation of postsynaptic membrane organisation|up-regulation of postsynaptic membrane organization|activation of postsynaptic membrane organization|positive regulation of post-synaptic membrane organization|positive regulation of postsynaptic membrane organisation|up regulation of postsynaptic membrane organisation|up regulation of postsynaptic membrane organization|upregulation of postsynaptic membrane organisation http://purl.obolibrary.org/obo/GO_1901628 UBERON:0013230 biolink:AnatomicalEntity nictitans gland A gland producing tears in a third eyelid in the corner of each eye. go-plus.json superficial gland of the third eyelid|glandula palpebra tertia superficialis|superficial gland of the nictitating membrane|gland of the third eyelid|gland of nictitating membrane http://purl.obolibrary.org/obo/UBERON_0013230 GO:1901629 biolink:BiologicalProcess regulation of presynaptic membrane organization Any process that modulates the frequency, rate or extent of presynaptic membrane organization. go-plus.json regulation of pre-synaptic membrane organization|regulation of presynaptic membrane organisation http://purl.obolibrary.org/obo/GO_1901629 GO:1901626 biolink:BiologicalProcess regulation of postsynaptic membrane organization Any process that modulates the frequency, rate or extent of postsynaptic membrane organization. go-plus.json regulation of post-synaptic membrane organization|regulation of postsynaptic membrane organisation http://purl.obolibrary.org/obo/GO_1901626 GO:1901627 biolink:BiologicalProcess negative regulation of postsynaptic membrane organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization. go-plus.json down regulation of postsynaptic membrane organization|inhibition of postsynaptic membrane organization|down-regulation of postsynaptic membrane organisation|negative regulation of postsynaptic membrane organisation|down-regulation of postsynaptic membrane organization|negative regulation of post-synaptic membrane organization|downregulation of postsynaptic membrane organisation|down regulation of postsynaptic membrane organisation|inhibition of postsynaptic membrane organisation|downregulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_1901627 GO:1901624 biolink:BiologicalProcess negative regulation of lymphocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis. go-plus.json down regulation of lymphocyte chemotaxis|downregulation of lymphocyte chemotaxis|down-regulation of lymphocyte chemotaxis|inhibition of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901624 GO:1901625 biolink:BiologicalProcess cellular response to ergosterol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901625 UBERON:0013235 biolink:AnatomicalEntity ventrum A major organism subdivisionthat is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane. go-plus.json ventral region of organism|ventral part of organism|ventral region|front|front of body proper http://purl.obolibrary.org/obo/UBERON_0013235 GO:1901622 biolink:BiologicalProcess positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. go-plus.json up-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|activation of hh signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|positive regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|upregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning http://purl.obolibrary.org/obo/GO_1901622 GO:0045138 biolink:BiologicalProcess nematode male tail tip morphogenesis The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome. go-plus.json tail tip morphogenesis|male tail morphogenesis|male tail tip morphogenesis http://purl.obolibrary.org/obo/GO_0045138 CHEBI:85382 biolink:ChemicalSubstance 1-heptadecanoyl-2-lauroyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85382 GO:0045139 biolink:BiologicalProcess obsolete copper sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json copper sensitivity/resistance http://purl.obolibrary.org/obo/GO_0045139 GO:1901623 biolink:BiologicalProcess regulation of lymphocyte chemotaxis Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_1901623 CHEBI:85383 biolink:ChemicalSubstance 1-heptadecanoyl-2-myristoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85383 GO:0045136 biolink:BiologicalProcess development of secondary sexual characteristics The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0045136 GO:1901620 biolink:BiologicalProcess regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. go-plus.json regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning http://purl.obolibrary.org/obo/GO_1901620 GO:1901621 biolink:BiologicalProcess negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. go-plus.json down regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|downregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hh signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signalling pathway involved in dorsal/ventral neural tube patterning http://purl.obolibrary.org/obo/GO_1901621 UBERON:0013238 biolink:AnatomicalEntity future glans go-plus.json http://purl.obolibrary.org/obo/UBERON_0013238 GO:0045137 biolink:BiologicalProcess development of primary sexual characteristics The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0045137 CHEBI:85385 biolink:ChemicalSubstance 1-heptadecanoyl-2-stearoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85385 GO:0045134 biolink:MolecularActivity uridine-diphosphatase activity Catalysis of the reaction: UDP + H2O = UMP + phosphate. MetaCyc:RXN-12197|RHEA:64876|KEGG_REACTION:R00155|EC:3.6.1.6 go-plus.json uridine diphosphatase activity|UDPase activity|UDP phosphohydrolase activity|uridine 5'-diphosphatase activity http://purl.obolibrary.org/obo/GO_0045134 CHEBI:85386 biolink:ChemicalSubstance 1-heptadecanoyl-2-palmitoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85386 UBERON:0013231 biolink:AnatomicalEntity sebaceous gland of eyelid Any of the sebaceous glands that are in the eyelid. Examples: gland of Zeis (services eyelashes), gland of Meibom (tarsal gland - unconnected to eyelids). go-plus.json http://purl.obolibrary.org/obo/UBERON_0013231 GO:0045135 biolink:MolecularActivity poly(beta-D-mannuronate) lyase activity Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. MetaCyc:4.2.2.3-RXN|EC:4.2.2.3 go-plus.json alginase activity|poly(beta-D-1,4-mannuronide) lyase activity|alginase I|alginate lyase I activity|alginate lyase activity|poly(mana) alginate lyase activity http://purl.obolibrary.org/obo/GO_0045135 UBERON:0013232 biolink:AnatomicalEntity serous acinus The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. go-plus.json acinus of serous gland http://purl.obolibrary.org/obo/UBERON_0013232 GO:0045132 biolink:BiologicalProcess meiotic chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0045132 GO:0045133 biolink:MolecularActivity 2,3-dihydroxybenzoate 3,4-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). RHEA:18477|EC:1.13.11.14|KEGG_REACTION:R01507|MetaCyc:1.13.11.14-RXN go-plus.json 2,3-dihydroxybenzoic oxygenase activity|2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)|2,3-dihydroxybenzoate oxygenase activity|2,3-dihydroxybenzoate 1,2-dioxygenase activity|o-pyrocatechuate oxygenase activity http://purl.obolibrary.org/obo/GO_0045133 GO:0060770 biolink:BiologicalProcess negative regulation of epithelial cell proliferation involved in prostate gland development Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. go-plus.json http://purl.obolibrary.org/obo/GO_0060770 GO:0060771 biolink:BiologicalProcess phyllotactic patterning The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis. go-plus.json http://purl.obolibrary.org/obo/GO_0060771 GO:0060772 biolink:BiologicalProcess leaf phyllotactic patterning The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0060772 GO:0060773 biolink:BiologicalProcess flower phyllotactic patterning The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium. go-plus.json http://purl.obolibrary.org/obo/GO_0060773 GO:0060774 biolink:BiologicalProcess auxin mediated signaling pathway involved in phyllotactic patterning The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem. go-plus.json auxin mediated signalling pathway involved in phyllotactic patterning http://purl.obolibrary.org/obo/GO_0060774 GO:0060775 biolink:BiologicalProcess planar cell polarity pathway involved in gastrula mediolateral intercalation The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0060775 UBERON:0013228 biolink:AnatomicalEntity sweat gland of eyelid Glands of Moll, also known as ciliary glands, are modified apocrine sweat glands that are found on the margin of the eyelid. They are next to the base of the eyelashes, and anterior to the Meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped. The glands of Moll are named after Dutch oculist Jacob Anton Moll (1832-1914). Glands of Moll empty into the adjacent lashes. Glands of Moll and Zeis secrete lipid that adds to the superficial layer of the tear film, retarding evaporation. The glands of Moll are prone to infection and blockage of its duct with sebum and cell debris. Blockage of the gland's duct causes swelling which can manifest itself as a stye. go-plus.json ciliary gland|ciliary sweat gland of eyelid|ciliary gland of moll|Moll's gland|gland of Moll http://purl.obolibrary.org/obo/UBERON_0013228 GO:0060776 biolink:BiologicalProcess simple leaf morphogenesis The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided. go-plus.json http://purl.obolibrary.org/obo/GO_0060776 UBERON:0013229 biolink:AnatomicalEntity eyelid gland Any gland that is part of an eyelid. This includes sebaceous glands (Zeis gland, tarsal gland) and sweat glands (Moll's gland). go-plus.json gland of eyelid http://purl.obolibrary.org/obo/UBERON_0013229 GO:0060777 biolink:BiologicalProcess compound leaf morphogenesis The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development. go-plus.json http://purl.obolibrary.org/obo/GO_0060777 GO:0060778 biolink:BiologicalProcess primary leaflet morphogenesis The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis. go-plus.json http://purl.obolibrary.org/obo/GO_0060778 GO:0060779 biolink:BiologicalProcess secondary leaflet morphogenesis The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet. go-plus.json http://purl.obolibrary.org/obo/GO_0060779 GO:0045141 biolink:BiologicalProcess meiotic telomere clustering The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis. go-plus.json bouquet biosynthesis|bouquet formation http://purl.obolibrary.org/obo/GO_0045141 GO:0045142 biolink:MolecularActivity triplex DNA binding Binding to a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination. go-plus.json http://purl.obolibrary.org/obo/GO_0045142 GO:1901639 biolink:BiologicalProcess obsolete XDP catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of XDP. go-plus.json XDP catabolism|XDP degradation|XDP breakdown http://purl.obolibrary.org/obo/GO_1901639 GO:0045140 biolink:MolecularActivity inositol phosphoceramide synthase activity Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide + diacylglycerol. MetaCyc:RXN3O-581|EC:2.7.1.227 go-plus.json IPC synthase activity http://purl.obolibrary.org/obo/GO_0045140 GO:1901637 biolink:BiologicalProcess obsolete positive regulation of maintenance of presynaptic active zone structure OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of presynaptic active zone structure. go-plus.json up regulation of maintenance of presynaptic active zone structure|upregulation of maintenance of presynaptic active zone structure|positive regulation of maintenance of presynaptic active zone structure|up-regulation of maintenance of presynaptic active zone structure|activation of maintenance of presynaptic active zone structure http://purl.obolibrary.org/obo/GO_1901637 GO:1901638 biolink:BiologicalProcess obsolete copper ion import into ascospore-type prospore OBSOLETE. Any copper ion import that takes place in ascospore-type prospore. go-plus.json copper ion import into ascospore-type prospore|copper ion uptake in ascospore-type prospore http://purl.obolibrary.org/obo/GO_1901638 GO:1901635 biolink:BiologicalProcess obsolete regulation of maintenance of presynaptic active zone structure OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of presynaptic active zone structure. go-plus.json regulation of maintenance of presynaptic active zone structure http://purl.obolibrary.org/obo/GO_1901635 GO:1901636 biolink:BiologicalProcess obsolete negative regulation of maintenance of presynaptic active zone structure OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of presynaptic active zone structure. go-plus.json down-regulation of maintenance of presynaptic active zone structure|downregulation of maintenance of presynaptic active zone structure|down regulation of maintenance of presynaptic active zone structure|inhibition of maintenance of presynaptic active zone structure|negative regulation of maintenance of presynaptic active zone structure http://purl.obolibrary.org/obo/GO_1901636 GO:1901633 biolink:BiologicalProcess negative regulation of synaptic vesicle membrane organization Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization. go-plus.json down-regulation of synaptic vesicle membrane organisation|negative regulation of synaptic vesicle membrane organisation|down regulation of SLMV biogenesis|downregulation of SLMV biogenesis|down-regulation of synaptic vesicle membrane organization|downregulation of synaptic vesicle membrane organisation|down regulation of synaptic vesicle membrane organisation|negative regulation of SLMV biogenesis|down regulation of synaptic vesicle membrane organization and biogenesis|down-regulation of SLMV biogenesis|inhibition of synaptic vesicle membrane organisation|downregulation of synaptic vesicle membrane organization|downregulation of synaptic vesicle membrane organization and biogenesis|down regulation of synaptic vesicle membrane organization|inhibition of synaptic vesicle membrane organization|inhibition of SLMV biogenesis|down-regulation of synaptic vesicle membrane organization and biogenesis|negative regulation of synaptic vesicle membrane organization and biogenesis|inhibition of synaptic vesicle membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_1901633 GO:0045149 biolink:BiologicalProcess acetoin metabolic process The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source. go-plus.json acetoin metabolism http://purl.obolibrary.org/obo/GO_0045149 GO:1901634 biolink:BiologicalProcess positive regulation of synaptic vesicle membrane organization Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization. go-plus.json upregulation of SLMV biogenesis|activation of synaptic vesicle membrane organization|up-regulation of synaptic vesicle membrane organization|up-regulation of synaptic vesicle membrane organization and biogenesis|positive regulation of synaptic vesicle membrane organisation|up regulation of synaptic vesicle membrane organisation|up regulation of SLMV biogenesis|positive regulation of SLMV biogenesis|upregulation of synaptic vesicle membrane organization and biogenesis|up regulation of synaptic vesicle membrane organization|activation of SLMV biogenesis|upregulation of synaptic vesicle membrane organisation|up-regulation of SLMV biogenesis|up regulation of synaptic vesicle membrane organization and biogenesis|positive regulation of synaptic vesicle membrane organization and biogenesis|upregulation of synaptic vesicle membrane organization|activation of synaptic vesicle membrane organisation|up-regulation of synaptic vesicle membrane organisation|activation of synaptic vesicle membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_1901634 GO:1901631 biolink:BiologicalProcess positive regulation of presynaptic membrane organization Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization. go-plus.json upregulation of presynaptic membrane organisation|upregulation of presynaptic membrane organization|positive regulation of pre-synaptic membrane organization|up regulation of presynaptic membrane organisation|activation of presynaptic membrane organisation|positive regulation of presynaptic membrane organisation|up regulation of presynaptic membrane organization|activation of presynaptic membrane organization|up-regulation of presynaptic membrane organisation|up-regulation of presynaptic membrane organization http://purl.obolibrary.org/obo/GO_1901631 GO:0045147 biolink:BiologicalProcess regulation of initiation of acetate catabolic process by acetate Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json regulation of initiation of acetate breakdown by acetate|regulation of initiation of acetate degradation by acetate http://purl.obolibrary.org/obo/GO_0045147 GO:0045148 biolink:MolecularActivity tripeptide aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide. EC:3.4.11.4|MetaCyc:3.4.11.4-RXN go-plus.json alanine-phenylalanine-proline arylamidase activity|peptidase B|peptidase T|aminoexotripeptidase activity|imidoendopeptidase activity|lymphopeptidase activity|aminotripeptidase activity http://purl.obolibrary.org/obo/GO_0045148 GO:1901632 biolink:BiologicalProcess regulation of synaptic vesicle membrane organization Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization. go-plus.json regulation of SLMV biogenesis|regulation of synaptic vesicle membrane organisation|regulation of synaptic vesicle membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_1901632 GO:0045145 biolink:MolecularActivity single-stranded DNA 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule. go-plus.json single-stranded DNA specific 5'-3' exodeoxyribonuclease activity|ssDNA-specific 5'-3' exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0045145 CHEBI:85375 biolink:ChemicalSubstance N-acetylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85375 chebi_ph7_3 CHEBI:12427 biolink:ChemicalSubstance N,N'-diacetylchitobiosyldiphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_12427 GO:1901630 biolink:BiologicalProcess negative regulation of presynaptic membrane organization Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization. go-plus.json down regulation of presynaptic membrane organisation|negative regulation of pre-synaptic membrane organization|downregulation of presynaptic membrane organisation|down regulation of presynaptic membrane organization|downregulation of presynaptic membrane organization|negative regulation of presynaptic membrane organisation|down-regulation of presynaptic membrane organisation|inhibition of presynaptic membrane organisation|down-regulation of presynaptic membrane organization|inhibition of presynaptic membrane organization http://purl.obolibrary.org/obo/GO_1901630 GO:0045146 biolink:BiologicalProcess initiation of acetate catabolic process by acetate The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json initiation of acetate degradation by acetate|initiation of acetate breakdown by acetate http://purl.obolibrary.org/obo/GO_0045146 CHEBI:85376 biolink:ChemicalSubstance N-octanoylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85376 chebi_ph7_3 GO:0045143 biolink:BiologicalProcess homologous chromosome segregation The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets. go-plus.json meiosis I, chromosome segregation http://purl.obolibrary.org/obo/GO_0045143 GO:0045144 biolink:BiologicalProcess meiotic sister chromatid segregation The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. go-plus.json meiosis II, chromosome segregation http://purl.obolibrary.org/obo/GO_0045144 CHEBI:85378 biolink:ChemicalSubstance N-oleoylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85378 chebi_ph7_3 GO:0060760 biolink:BiologicalProcess positive regulation of response to cytokine stimulus Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0060760 GO:0060761 biolink:BiologicalProcess negative regulation of response to cytokine stimulus Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0060761 GO:0060762 biolink:BiologicalProcess regulation of branching involved in mammary gland duct morphogenesis Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0060762 GO:0060763 biolink:BiologicalProcess mammary duct terminal end bud growth The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty. go-plus.json http://purl.obolibrary.org/obo/GO_0060763 GO:0060764 biolink:BiologicalProcess cell-cell signaling involved in mammary gland development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. go-plus.json cell-cell signalling involved in mammary gland development http://purl.obolibrary.org/obo/GO_0060764 UBERON:0013218 biolink:AnatomicalEntity rete mirabile A rete mirabile (Latin for 'wonderful net'; plural retia mirabilia) is a complex of arteries and veins lying very close to each other, found in some vertebrates. The rete mirabile utilizes countercurrent blood flow within the net (blood flowing in opposite directions. ) It exchanges heat, ions, or gases between vessel walls so that the two bloodstreams within the rete maintain a gradient with respect to temperature, or concentration of gases or solutes. go-plus.json red body|retie mirabilia|rete mirabilis|red gland|wonderful net|rete mirabilia http://purl.obolibrary.org/obo/UBERON_0013218 GO:0060765 biolink:BiologicalProcess regulation of androgen receptor signaling pathway Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway. go-plus.json regulation of androgen receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060765 GO:0060766 biolink:BiologicalProcess negative regulation of androgen receptor signaling pathway Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway. go-plus.json negative regulation of androgen receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060766 GO:0060767 biolink:BiologicalProcess epithelial cell proliferation involved in prostate gland development The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. go-plus.json http://purl.obolibrary.org/obo/GO_0060767 GO:0060768 biolink:BiologicalProcess regulation of epithelial cell proliferation involved in prostate gland development Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. go-plus.json http://purl.obolibrary.org/obo/GO_0060768 GO:0060769 biolink:BiologicalProcess positive regulation of epithelial cell proliferation involved in prostate gland development Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. go-plus.json http://purl.obolibrary.org/obo/GO_0060769 GO:0045152 biolink:MolecularActivity antisigma factor binding Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator. go-plus.json antisigma factor antagonist activity http://purl.obolibrary.org/obo/GO_0045152 GO:0045153 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045153 GO:0045150 biolink:BiologicalProcess acetoin catabolic process The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone. go-plus.json acetoin breakdown|acetoin catabolism|acetoin degradation http://purl.obolibrary.org/obo/GO_0045150 GO:0045151 biolink:BiologicalProcess acetoin biosynthetic process The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone. go-plus.json acetoin anabolism|acetoin synthesis|acetoin formation|acetoin biosynthesis http://purl.obolibrary.org/obo/GO_0045151 GO:1901648 biolink:BiologicalProcess regulation of actomyosin contractile ring localization Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization. go-plus.json regulation of contractile ring localization involved in cell cycle cytokinesis|regulation of contractile ring localisation involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_1901648 GO:1901649 biolink:BiologicalProcess negative regulation of actomyosin contractile ring localization Any process that stops, prevents or reduces the frequency, rate or extent of actomyosin contractile ring localization. go-plus.json negative regulation of contractile ring localization involved in cell cycle cytokinesis|down-regulation of contractile ring localization involved in cell cycle cytokinesis|downregulation of actomyosin contractile ring localization|negative regulation of contractile ring localisation involved in cell cycle cytokinesis|down-regulation of contractile ring localisation involved in cell cycle cytokinesis|downregulation of contractile ring localization involved in cell cycle cytokinesis|down regulation of actomyosin contractile ring localization|inhibition of actomyosin contractile ring localization|down regulation of contractile ring localization involved in cell cycle cytokinesis|downregulation of contractile ring localisation involved in cell cycle cytokinesis|down regulation of contractile ring localisation involved in cell cycle cytokinesis|inhibition of contractile ring localization involved in cell cycle cytokinesis|inhibition of contractile ring localisation involved in cell cycle cytokinesis|down-regulation of actomyosin contractile ring localization http://purl.obolibrary.org/obo/GO_1901649 GO:1901646 biolink:BiologicalProcess negative regulation of synoviocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation. go-plus.json inhibition of synoviocyte proliferation|down regulation of synoviocyte proliferation|downregulation of synoviocyte proliferation|down-regulation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_1901646 GO:1901647 biolink:BiologicalProcess positive regulation of synoviocyte proliferation Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation. go-plus.json up-regulation of synoviocyte proliferation|upregulation of synoviocyte proliferation|up regulation of synoviocyte proliferation|activation of synoviocyte proliferation http://purl.obolibrary.org/obo/GO_1901647 GO:1901644 biolink:BiologicalProcess obsolete positive regulation of tRNA methylation in response to nitrogen starvation OBSOLETE. Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation. go-plus.json upregulation of tRNA methylation in response to nitrogen starvation|up regulation of tRNA methylation in response to nitrogen starvation|activation of tRNA methylation in response to nitrogen starvation|up-regulation of tRNA methylation in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_1901644 GO:1901645 biolink:BiologicalProcess regulation of synoviocyte proliferation Any process that modulates the frequency, rate or extent of synoviocyte proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_1901645 GO:1901642 biolink:BiologicalProcess nucleoside transmembrane transport The directed movement of nucleoside across a membrane. go-plus.json nucleoside membrane transport http://purl.obolibrary.org/obo/GO_1901642 GO:0045158 biolink:MolecularActivity electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II. go-plus.json cytochrome|cytochrome f|cytochrome b/b6|cytochrome b6 http://purl.obolibrary.org/obo/GO_0045158 GO:1901643 biolink:BiologicalProcess obsolete regulation of tRNA methylation in response to nitrogen starvation OBSOLETE. Any process that modulates the frequency, rate or extent of tRNA methylation in response to nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1901643 GO:0045159 biolink:MolecularActivity myosin II binding Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin. go-plus.json http://purl.obolibrary.org/obo/GO_0045159 GO:0045156 biolink:MolecularActivity electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis. go-plus.json cytochrome|cytochrome bc1 complex http://purl.obolibrary.org/obo/GO_0045156 GO:1901640 biolink:MolecularActivity XTP binding Binding to XTP. go-plus.json http://purl.obolibrary.org/obo/GO_1901640 GO:0045157 biolink:MolecularActivity electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis. go-plus.json cytochrome http://purl.obolibrary.org/obo/GO_0045157 GO:1901641 biolink:MolecularActivity ITP binding Binding to ITP. go-plus.json http://purl.obolibrary.org/obo/GO_1901641 GO:0060790 biolink:BiologicalProcess tooth placode formation The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060790 GO:0045154 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045154 GO:0060791 biolink:BiologicalProcess sebaceous gland placode formation The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060791 GO:0060792 biolink:BiologicalProcess sweat gland development The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. go-plus.json http://purl.obolibrary.org/obo/GO_0060792 GO:0045155 biolink:MolecularActivity obsolete electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity OBSOLETE. Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex. go-plus.json cytochrome|cytochrome c http://purl.obolibrary.org/obo/GO_0045155 GO:0060793 biolink:BiologicalProcess sweat gland placode formation The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060793 GO:0060794 biolink:BiologicalProcess leaflet morphogenesis The process in which the anatomical structures of the leaflet are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060794 GO:0060795 biolink:BiologicalProcess cell fate commitment involved in formation of primary germ layer The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0060795 GO:0060796 biolink:BiologicalProcess obsolete regulation of transcription involved in primary germ layer cell fate commitment OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060796 GO:0060797 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate. go-plus.json transforming growth factor beta receptor signalling pathway involved in primary germ layer cell fate commitment http://purl.obolibrary.org/obo/GO_0060797 GO:0060798 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate. go-plus.json transforming growth factor beta receptor signalling pathway involved in mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0060798 GO:0060799 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate. go-plus.json transforming growth factor beta receptor signalling pathway involved in endodermal cell fate specification http://purl.obolibrary.org/obo/GO_0060799 GO:0070118 biolink:CellularComponent organellar chromatophore thylakoid membrane The lipid bilayer membrane of any thylakoid within an organellar chromatophore. go-plus.json Paulinella-type chromatophore thylakoid membrane http://purl.obolibrary.org/obo/GO_0070118 GO:0070119 biolink:MolecularActivity ciliary neurotrophic factor binding Binding to the cytokine ciliary neurotrophic factor. go-plus.json CNTF binding http://purl.obolibrary.org/obo/GO_0070119 GO:0070116 biolink:CellularComponent organellar chromatophore thylakoid A thylakoid located in an organellar chromatophore. go-plus.json Paulinella-type chromatophore thylakoid http://purl.obolibrary.org/obo/GO_0070116 GO:0070117 biolink:CellularComponent organellar chromatophore thylakoid lumen The volume enclosed by an organellar chromatophore thylakoid membrane. go-plus.json Paulinella-type chromatophore thylakoid lumen http://purl.obolibrary.org/obo/GO_0070117 GO:0070114 biolink:CellularComponent organellar chromatophore outer membrane The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore. go-plus.json Paulinella-type chromatophore outer membrane http://purl.obolibrary.org/obo/GO_0070114 GO:0070115 biolink:CellularComponent organellar chromatophore intermembrane space The region between the inner and outer lipid bilayers that surround an organellar chromatophore. go-plus.json Paulinella-type chromatophore intermembrane space http://purl.obolibrary.org/obo/GO_0070115 GO:0070112 biolink:CellularComponent organellar chromatophore membrane Either of the lipid bilayers that surround an organellar chromatophore. go-plus.json Paulinella-type chromatophore membrane http://purl.obolibrary.org/obo/GO_0070112 GO:0070113 biolink:CellularComponent organellar chromatophore inner membrane The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore. go-plus.json Paulinella-type chromatophore inner membrane http://purl.obolibrary.org/obo/GO_0070113 GO:0070110 biolink:CellularComponent ciliary neurotrophic factor receptor complex A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR. go-plus.json http://purl.obolibrary.org/obo/GO_0070110 GO:0070111 biolink:CellularComponent organellar chromatophore A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora. go-plus.json Paulinella-type chromatophore http://purl.obolibrary.org/obo/GO_0070111 GO:0045163 biolink:BiologicalProcess clustering of voltage-gated potassium channels The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode. go-plus.json voltage-gated potassium channel clustering|clustering of voltage-dependent potassium channels|Kv channel clustering|clustering of voltage gated potassium channels http://purl.obolibrary.org/obo/GO_0045163 GO:0045164 biolink:MolecularActivity obsolete secretin (sensu Mammalia) OBSOLETE. Secretin is a hormone that takes part in the digestion process. It also has effects on organs other than gastrointestinal tract. go-plus.json secretin (sensu Mammalia) http://purl.obolibrary.org/obo/GO_0045164 GO:0045161 biolink:BiologicalProcess neuronal ion channel clustering The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation. go-plus.json http://purl.obolibrary.org/obo/GO_0045161 GO:0045162 biolink:BiologicalProcess clustering of voltage-gated sodium channels The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization. go-plus.json Nav channel clustering|clustering of voltage gated sodium channels|clustering of voltage-dependent sodium channels|voltage-gated sodium channel clustering http://purl.obolibrary.org/obo/GO_0045162 GO:1901659 biolink:BiologicalProcess glycosyl compound biosynthetic process The chemical reactions and pathways resulting in the formation of glycosyl compound. go-plus.json glycosyl compound biosynthesis|glycosyl compound anabolism|glycosyl compound synthesis|glycosyl compound formation http://purl.obolibrary.org/obo/GO_1901659 GO:0045160 biolink:CellularComponent myosin I complex A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement. go-plus.json http://purl.obolibrary.org/obo/GO_0045160 UBERON:0013280 biolink:AnatomicalEntity diaphysis of tibia A diaphysis that is part of a tibia. go-plus.json body of the tibia|shaft of tibia|tibial diaphysis|shaft of tibia|body of tibia|corpus tibiae http://purl.obolibrary.org/obo/UBERON_0013280 GO:1901657 biolink:BiologicalProcess glycosyl compound metabolic process The chemical reactions and pathways involving glycosyl compound. go-plus.json glycosyl compound metabolism http://purl.obolibrary.org/obo/GO_1901657 GO:1901658 biolink:BiologicalProcess glycosyl compound catabolic process The chemical reactions and pathways resulting in the breakdown of glycosyl compound. go-plus.json glycosyl compound degradation|glycosyl compound catabolism|glycosyl compound breakdown http://purl.obolibrary.org/obo/GO_1901658 GO:1901655 biolink:BiologicalProcess cellular response to ketone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901655 GO:1901656 biolink:BiologicalProcess glycoside transport The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901656 GO:1901653 biolink:BiologicalProcess cellular response to peptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901653 GO:0045169 biolink:CellularComponent fusome A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0045169 GO:1901654 biolink:BiologicalProcess response to ketone A response that results in a state of tolerance to ketone. go-plus.json process resulting in tolerance to ketone http://purl.obolibrary.org/obo/GO_1901654 GO:0045167 biolink:BiologicalProcess asymmetric protein localization involved in cell fate determination Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types. go-plus.json asymmetric protein localisation involved in cell fate determination|asymmetric protein localization involved in cell fate commitment|asymmetric protein localization resulting in cell fate commitment|cell fate commitment, asymmetric protein localization http://purl.obolibrary.org/obo/GO_0045167 GO:1901651 biolink:BiologicalProcess regulation of mitotic chromosome decondensation Any process that modulates the frequency, rate or extent of mitotic chromosome decondensation. go-plus.json http://purl.obolibrary.org/obo/GO_1901651 GO:0045168 biolink:BiologicalProcess cell-cell signaling involved in cell fate commitment Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. go-plus.json cell-cell signaling resulting in cell fate commitment|cell fate commitment, cell-cell signalling|cell-cell signalling involved in cell fate specification|cell fate commitment, cell-cell signaling|cell-cell signaling during in cell fate commitment|cell-cell signalling resulting in cell fate commitment|cell-cell signalling during cell fate commitment http://purl.obolibrary.org/obo/GO_0045168 GO:1901652 biolink:BiologicalProcess response to peptide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901652 GO:0060780 biolink:BiologicalProcess intercalary leaflet morphogenesis The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets. go-plus.json http://purl.obolibrary.org/obo/GO_0060780 GO:0045165 biolink:BiologicalProcess cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. go-plus.json http://purl.obolibrary.org/obo/GO_0045165 GO:1901650 biolink:BiologicalProcess positive regulation of actomyosin contractile ring localization Any process that activates or increases the frequency, rate or extent of actomyosin contractile ring localization. go-plus.json up-regulation of actomyosin contractile ring localization|activation of actomyosin contractile ring localization|upregulation of contractile ring localisation involved in cell cycle cytokinesis|up-regulation of contractile ring localization involved in cell cycle cytokinesis|activation of contractile ring localization involved in cell cycle cytokinesis|up-regulation of contractile ring localisation involved in cell cycle cytokinesis|up regulation of actomyosin contractile ring localization|positive regulation of contractile ring localization involved in cell cycle cytokinesis|up regulation of contractile ring localization involved in cell cycle cytokinesis|activation of contractile ring localisation involved in cell cycle cytokinesis|positive regulation of contractile ring localisation involved in cell cycle cytokinesis|upregulation of actomyosin contractile ring localization|up regulation of contractile ring localisation involved in cell cycle cytokinesis|upregulation of contractile ring localization involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_1901650 GO:0060781 biolink:BiologicalProcess mesenchymal cell proliferation involved in prostate gland development The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. go-plus.json http://purl.obolibrary.org/obo/GO_0060781 GO:0045166 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045166 GO:0060782 biolink:BiologicalProcess regulation of mesenchymal cell proliferation involved in prostate gland development Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json http://purl.obolibrary.org/obo/GO_0060782 GO:0060783 biolink:BiologicalProcess mesenchymal smoothened signaling pathway involved in prostate gland development The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development. go-plus.json mesenchymal hh signaling pathway involved in prostate gland development|mesenchymal smoothened signalling pathway involved in prostate gland development|mesenchymal hedgehog signaling pathway involved in prostate gland development http://purl.obolibrary.org/obo/GO_0060783 GO:0060784 biolink:BiologicalProcess regulation of cell proliferation involved in tissue homeostasis Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060784 GO:0060785 biolink:BiologicalProcess regulation of apoptosis involved in tissue homeostasis Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060785 GO:0070109 biolink:BiologicalProcess positive regulation of interleukin-27-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor. go-plus.json positive regulation of interleukin-27-mediated signalling pathway|positive regulation of IL27RA/IL6ST signaling pathway|positive regulation of IL-27-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070109 GO:0060786 biolink:BiologicalProcess regulation of cell differentiation involved in tissue homeostasis Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060786 GO:0060787 biolink:BiologicalProcess positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate. go-plus.json positive regulation of posterior neural plate formation by FGF receptor signaling pathway|positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060787 NCBITaxon:9005 biolink:OrganismalEntity Phasianidae go-plus.json turkeys http://purl.obolibrary.org/obo/NCBITaxon_9005 GO:0060788 biolink:BiologicalProcess ectodermal placode formation The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0060788 GO:0070107 biolink:BiologicalProcess regulation of interleukin-27-mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor. go-plus.json regulation of IL27RA/IL6ST signaling pathway|regulation of IL-27-mediated signaling pathway|regulation of interleukin-27-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070107 GO:0060789 biolink:BiologicalProcess hair follicle placode formation The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. go-plus.json http://purl.obolibrary.org/obo/GO_0060789 GO:0070108 biolink:BiologicalProcess negative regulation of interleukin-27-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor. go-plus.json negative regulation of IL27RA/IL6ST signaling pathway|negative regulation of IL-27-mediated signaling pathway|negative regulation of interleukin-27-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070108 GO:0070105 biolink:BiologicalProcess positive regulation of interleukin-6-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor. go-plus.json positive regulation of IL-6-mediated signaling pathway|positive regulation of interleukin-6-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070105 GO:0070106 biolink:BiologicalProcess interleukin-27-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL27RA/IL6ST signaling pathway|IL-27-mediated signaling pathway|interleukin-27-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070106 GO:0070103 biolink:BiologicalProcess regulation of interleukin-6-mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor. go-plus.json regulation of IL-6-mediated signaling pathway|regulation of interleukin-6-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070103 GO:0070104 biolink:BiologicalProcess negative regulation of interleukin-6-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor. go-plus.json negative regulation of interleukin-6-mediated signalling pathway|negative regulation of IL-6-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070104 GO:0070101 biolink:BiologicalProcess positive regulation of chemokine-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor. go-plus.json positive regulation of chemokine-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070101 GO:0070102 biolink:BiologicalProcess interleukin-6-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-6-mediated signalling pathway|IL-6-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070102 GO:0070100 biolink:BiologicalProcess negative regulation of chemokine-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor. go-plus.json negative regulation of chemokine-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070100 GO:0045174 biolink:MolecularActivity glutathione dehydrogenase (ascorbate) activity Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide. Reactome:R-HSA-198813|KEGG_REACTION:R01108|MetaCyc:1.8.5.1-RXN|RHEA:24424|EC:1.8.5.1 go-plus.json glutathione:dehydroascorbate oxidoreductase activity|dehydroascorbic reductase activity|dehydroascorbate reductase activity|DHA reductase activity|glutathione:dehydroascorbic acid oxidoreductase activity|dehydroascorbic acid reductase activity|glutathione dehydroascorbate reductase activity|GDOR http://purl.obolibrary.org/obo/GO_0045174 GO:0070130 biolink:BiologicalProcess negative regulation of mitochondrial translation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. go-plus.json negative regulation of mitochondrial protein anabolism|negative regulation of mitochondrial protein synthesis|negative regulation of mitochondrial protein formation|negative regulation of mitochondrial protein biosynthesis http://purl.obolibrary.org/obo/GO_0070130 GO:0045175 biolink:BiologicalProcess basal protein localization Any process in which a protein is transported to, or maintained in, basal regions of the cell. go-plus.json establishment and maintenance of basal protein localization|basal protein localisation|establishment and maintenance of protein localization in basal part of cell http://purl.obolibrary.org/obo/GO_0045175 GO:0070131 biolink:BiologicalProcess positive regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. go-plus.json positive regulation of mitochondrial protein anabolism|positive regulation of mitochondrial protein synthesis|positive regulation of mitochondrial protein formation|positive regulation of mitochondrial protein biosynthesis http://purl.obolibrary.org/obo/GO_0070131 GO:0045172 biolink:CellularComponent germline ring canal Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells. go-plus.json http://purl.obolibrary.org/obo/GO_0045172 GO:0045173 biolink:BiologicalProcess O-sialoglycoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities. go-plus.json O-sialoglycoprotein catabolism|O-sialoglycoprotein degradation|O-sialoglycoprotein breakdown http://purl.obolibrary.org/obo/GO_0045173 GO:0045170 biolink:CellularComponent spectrosome A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome. go-plus.json http://purl.obolibrary.org/obo/GO_0045170 GO:0045171 biolink:CellularComponent intercellular bridge A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised. go-plus.json http://purl.obolibrary.org/obo/GO_0045171 GO:1901668 biolink:BiologicalProcess regulation of superoxide dismutase activity Any process that modulates the frequency, rate or extent of superoxide dismutase activity. go-plus.json regulation of zinc superoxide oxidoreductase|regulation of hemocuprein|regulation of copper, zinc superoxide dismutase activity|regulation of cuprein|regulation of Mn, Fe superoxide dismutase|regulation of SODS|regulation of nickel superoxide dismutase activity|regulation of SOD-4|regulation of Cu-Zn superoxide dismutase activity|regulation of SOD-3|regulation of iron superoxide dismutase activity|regulation of hepatocuprein|regulation of SOD-2|regulation of SOD-1|regulation of superoxide dismutase I|regulation of manganese superoxide oxidoreductase|regulation of Cu,Zn-SOD|regulation of SOD|regulation of superoxide dismutase II|regulation of cytocuprein|regulation of SODF|regulation of Mn-SOD|regulation of Fe-SOD|regulation of erythrocuprein|regulation of nickel superoxide oxidoreductase|regulation of manganese superoxide dismutase activity|regulation of ferrisuperoxide dismutase activity|regulation of iron superoxide oxidoreductase|regulation of superoxide:superoxide oxidoreductase activity http://purl.obolibrary.org/obo/GO_1901668 GO:1901666 biolink:BiologicalProcess positive regulation of NAD+ ADP-ribosyltransferase activity Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. go-plus.json up-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|positive regulation of NAD ADP-ribosyltransferase activity|activation of poly(ADP-ribose) synthetase activity|upregulation of poly(ADP-ribose) synthase activity|up-regulation of ADP-ribosyltransferase (polymerizing) activity|up regulation of poly(ADP-ribose)polymerase activity|activation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|activation of NAD ADP-ribosyltransferase activity|up regulation of NAD+ ADP-ribosyltransferase activity|positive regulation of poly(ADP-ribose)polymerase activity|positive regulation of poly(ADP-ribose) synthetase activity|upregulation of poly(adenosine diphosphate ribose) polymerase activity|positive regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up regulation of poly(ADP-ribose) synthetase activity|activation of ADP-ribosyltransferase (polymerizing) activity|up-regulation of NAD ADP-ribosyltransferase activity|up regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up-regulation of poly(ADP-ribose) synthase activity|activation of poly(ADP-ribose)polymerase activity|positive regulation of ADP-ribosyltransferase (polymerizing) activity|upregulation of NAD+ ADP-ribosyltransferase activity|up-regulation of poly(adenosine diphosphate ribose) polymerase activity|up regulation of ADP-ribosyltransferase (polymerizing) activity|activation of poly(ADP-ribose) synthase activity|up-regulation of poly(ADP-ribose)polymerase activity|upregulation of poly(ADP-ribose) synthetase activity|upregulation of NAD ADP-ribosyltransferase activity|upregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|positive regulation of poly(ADP-ribose) synthase activity|activation of poly(adenosine diphosphate ribose) polymerase activity|activation of NAD+ ADP-ribosyltransferase activity|up-regulation of NAD+ ADP-ribosyltransferase activity|up regulation of poly(ADP-ribose) synthase activity|upregulation of ADP-ribosyltransferase (polymerizing) activity|upregulation of poly(ADP-ribose)polymerase activity|positive regulation of poly(adenosine diphosphate ribose) polymerase activity|up-regulation of poly(ADP-ribose) synthetase activity|up regulation of NAD ADP-ribosyltransferase activity|up regulation of poly(adenosine diphosphate ribose) polymerase activity http://purl.obolibrary.org/obo/GO_1901666 UBERON:0013279 biolink:AnatomicalEntity diaphysis of fibula A diaphysis that is part of a fibula[Automatically generated definition]. go-plus.json body of fibula|shaft of fibula|fibula diaphysis|corpus fibulae http://purl.obolibrary.org/obo/UBERON_0013279 GO:1901667 biolink:BiologicalProcess negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration. go-plus.json downregulation of satellite cell activation involved in skeletal muscle regeneration|down regulation of satellite cell activation involved in skeletal muscle regeneration|inhibition of satellite cell activation involved in skeletal muscle regeneration|down-regulation of satellite cell activation involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_1901667 GO:1901664 biolink:BiologicalProcess regulation of NAD+ ADP-ribosyltransferase activity Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. go-plus.json regulation of poly(ADP-ribose)polymerase activity|regulation of poly(adenosine diphosphate ribose) polymerase activity|regulation of poly(ADP-ribose) synthetase activity|regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|regulation of ADP-ribosyltransferase (polymerizing) activity|regulation of NAD ADP-ribosyltransferase activity|regulation of poly(ADP-ribose) synthase activity http://purl.obolibrary.org/obo/GO_1901664 GO:1901665 biolink:BiologicalProcess negative regulation of NAD+ ADP-ribosyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. go-plus.json down regulation of poly(ADP-ribose) synthase activity|downregulation of poly(adenosine diphosphate ribose) polymerase activity|downregulation of poly(ADP-ribose)polymerase activity|negative regulation of poly(ADP-ribose) synthetase activity|negative regulation of NAD ADP-ribosyltransferase activity|down-regulation of NAD ADP-ribosyltransferase activity|down-regulation of poly(ADP-ribose) synthetase activity|down regulation of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|negative regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of poly(ADP-ribose) synthase activity|downregulation of NAD+ ADP-ribosyltransferase activity|down-regulation of ADP-ribosyltransferase (polymerizing) activity|down-regulation of poly(ADP-ribose)polymerase activity|negative regulation of ADP-ribosyltransferase (polymerizing) activity|negative regulation of poly(ADP-ribose)polymerase activity|inhibition of poly(adenosine diphosphate ribose) polymerase activity|down regulation of NAD+ ADP-ribosyltransferase activity|downregulation of poly(ADP-ribose) synthetase activity|inhibition of NAD+ ADP-ribosyltransferase activity|downregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of NAD ADP-ribosyltransferase activity|down regulation of poly(ADP-ribose) synthetase activity|down-regulation of poly(ADP-ribose) synthase activity|down regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|negative regulation of poly(ADP-ribose) synthase activity|downregulation of ADP-ribosyltransferase (polymerizing) activity|down regulation of NAD ADP-ribosyltransferase activity|inhibition of poly(ADP-ribose)polymerase activity|down regulation of ADP-ribosyltransferase (polymerizing) activity|negative regulation of poly(adenosine diphosphate ribose) polymerase activity|inhibition of poly(ADP-ribose) synthetase activity|down-regulation of poly(adenosine diphosphate ribose) polymerase activity|inhibition of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|downregulation of NAD ADP-ribosyltransferase activity|downregulation of poly(ADP-ribose) synthase activity|down regulation of poly(ADP-ribose)polymerase activity|inhibition of ADP-ribosyltransferase (polymerizing) activity|down-regulation of NAD+ ADP-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_1901665 GO:1901662 biolink:BiologicalProcess quinone catabolic process The chemical reactions and pathways resulting in the breakdown of quinone. go-plus.json quinone breakdown|quinone cofactor catabolism|quinone catabolism|quinone cofactor degradation|quinone cofactor breakdown|quinone cofactor catabolic process|quinone degradation http://purl.obolibrary.org/obo/GO_1901662 GO:0045178 biolink:CellularComponent basal part of cell The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0045178 goslim_pir GO:0045179 biolink:CellularComponent apical cortex The region that lies just beneath the plasma membrane on the apical edge of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0045179 GO:1901663 biolink:BiologicalProcess quinone biosynthetic process The chemical reactions and pathways resulting in the formation of quinone. go-plus.json quinone cofactor synthesis|quinone cofactor formation|quinone cofactor biosynthesis|quinone cofactor biosynthetic process|quinone anabolism|quinone synthesis|quinone biosynthesis|quinone formation|quinone cofactor anabolism http://purl.obolibrary.org/obo/GO_1901663 GO:0045176 biolink:BiologicalProcess apical protein localization Any process in which a protein is transported to, or maintained in, apical regions of the cell. go-plus.json establishment and maintenance of apical protein localization|establishment and maintenance of protein localization in apical part of cell|apical protein localisation http://purl.obolibrary.org/obo/GO_0045176 GO:1901660 biolink:BiologicalProcess calcium ion export The directed movement of calcium ion out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_1901660 GO:1901661 biolink:BiologicalProcess quinone metabolic process The chemical reactions and pathways involving quinone. go-plus.json quinone cofactor metabolism|quinone metabolism|quinone cofactor metabolic process http://purl.obolibrary.org/obo/GO_1901661 GO:0045177 biolink:CellularComponent apical part of cell The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue. go-plus.json apical region of cell http://purl.obolibrary.org/obo/GO_0045177 goslim_pir GO:1901670 biolink:BiologicalProcess negative regulation of superoxide dismutase activity Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity. go-plus.json down-regulation of SOD-4|negative regulation of SOD-4|downregulation of Mn-SOD|inhibition of superoxide:superoxide oxidoreductase activity|inhibition of manganese superoxide dismutase activity|down-regulation of SOD-3|negative regulation of SOD-3|inhibition of iron superoxide dismutase activity|downregulation of superoxide dismutase II|downregulation of cytocuprein|down-regulation of SOD-2|negative regulation of SOD-2|down-regulation of Cu-Zn superoxide dismutase activity|down-regulation of zinc superoxide oxidoreductase|downregulation of Fe-SOD|down regulation of SODF|down-regulation of hepatocuprein|negative regulation of Cu-Zn superoxide dismutase activity|negative regulation of zinc superoxide oxidoreductase|negative regulation of hepatocuprein|down-regulation of SOD-1|negative regulation of SOD-1|inhibition of superoxide dismutase I|downregulation of erythrocuprein|negative regulation of copper, zinc superoxide dismutase activity|down regulation of Mn-SOD|down-regulation of copper, zinc superoxide dismutase activity|inhibition of hemocuprein|inhibition of cuprein|negative regulation of manganese superoxide oxidoreductase|downregulation of nickel superoxide oxidoreductase|down-regulation of manganese superoxide oxidoreductase|down regulation of Fe-SOD|negative regulation of Cu,Zn-SOD|down-regulation of Cu,Zn-SOD|downregulation of iron superoxide oxidoreductase|negative regulation of SOD|down-regulation of SOD|down regulation of erythrocuprein|down regulation of manganese superoxide dismutase activity|down regulation of superoxide:superoxide oxidoreductase activity|down-regulation of SODS|downregulation of ferrisuperoxide dismutase activity|negative regulation of SODS|inhibition of SODF|down regulation of superoxide dismutase activity|down regulation of nickel superoxide oxidoreductase|inhibition of Mn, Fe superoxide dismutase|down-regulation of cytocuprein|down-regulation of superoxide dismutase II|negative regulation of superoxide dismutase II|negative regulation of cytocuprein|downregulation of superoxide:superoxide oxidoreductase activity|down regulation of iron superoxide oxidoreductase|inhibition of Mn-SOD|downregulation of zinc superoxide oxidoreductase|down-regulation of nickel superoxide dismutase activity|down regulation of hemocuprein|downregulation of manganese superoxide dismutase activity|negative regulation of nickel superoxide dismutase activity|down regulation of ferrisuperoxide dismutase activity|inhibition of SOD-4|down regulation of cuprein|negative regulation of iron superoxide dismutase activity|downregulation of superoxide dismutase activity|inhibition of SOD-3|downregulation of copper, zinc superoxide dismutase activity|down-regulation of iron superoxide dismutase activity|inhibition of Fe-SOD|inhibition of SOD-2|inhibition of hepatocuprein|inhibition of erythrocuprein|inhibition of Cu-Zn superoxide dismutase activity|downregulation of hemocuprein|down regulation of zinc superoxide oxidoreductase|inhibition of SOD-1|negative regulation of superoxide dismutase I|down-regulation of superoxide dismutase I|downregulation of cuprein|inhibition of nickel superoxide oxidoreductase|downregulation of SODS|down regulation of copper, zinc superoxide dismutase activity|inhibition of manganese superoxide oxidoreductase|down regulation of Mn, Fe superoxide dismutase|inhibition of iron superoxide oxidoreductase|inhibition of Cu,Zn-SOD|inhibition of SOD|inhibition of ferrisuperoxide dismutase activity|down regulation of SOD-4|negative regulation of superoxide:superoxide oxidoreductase activity|down-regulation of manganese superoxide dismutase activity|down-regulation of superoxide:superoxide oxidoreductase activity|down regulation of SOD-3|downregulation of nickel superoxide dismutase activity|negative regulation of manganese superoxide dismutase activity|down regulation of Cu-Zn superoxide dismutase activity|down-regulation of SODF|downregulation of Mn, Fe superoxide dismutase|down regulation of SODS|down regulation of SOD-2|negative regulation of SODF|down regulation of hepatocuprein|inhibition of superoxide dismutase II|down-regulation of superoxide dismutase activity|down regulation of SOD-1|downregulation of iron superoxide dismutase activity|inhibition of cytocuprein|inhibition of zinc superoxide oxidoreductase|down-regulation of Mn-SOD|negative regulation of Mn-SOD|downregulation of SOD-4|down regulation of nickel superoxide dismutase activity|down regulation of manganese superoxide oxidoreductase|downregulation of superoxide dismutase I|down-regulation of hemocuprein|negative regulation of hemocuprein|downregulation of SOD-3|inhibition of copper, zinc superoxide dismutase activity|down regulation of Cu,Zn-SOD|negative regulation of Fe-SOD|downregulation of hepatocuprein|negative regulation of cuprein|down-regulation of cuprein|down-regulation of Fe-SOD|downregulation of SOD-2|downregulation of Cu-Zn superoxide dismutase activity|down regulation of SOD|down regulation of iron superoxide dismutase activity|negative regulation of erythrocuprein|downregulation of SOD-1|down-regulation of erythrocuprein|negative regulation of nickel superoxide oxidoreductase|inhibition of SODS|downregulation of manganese superoxide oxidoreductase|down-regulation of nickel superoxide oxidoreductase|down regulation of superoxide dismutase I|inhibition of superoxide dismutase activity|downregulation of Cu,Zn-SOD|down regulation of cytocuprein|down regulation of superoxide dismutase II|downregulation of SOD|down-regulation of Mn, Fe superoxide dismutase|downregulation of SODF|down-regulation of iron superoxide oxidoreductase|negative regulation of iron superoxide oxidoreductase|negative regulation of Mn, Fe superoxide dismutase|inhibition of nickel superoxide dismutase activity|negative regulation of ferrisuperoxide dismutase activity|down-regulation of ferrisuperoxide dismutase activity http://purl.obolibrary.org/obo/GO_1901670 GO:0070138 biolink:MolecularActivity ubiquitin-like protein-specific isopeptidase activity Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated. go-plus.json small conjugating protein-specific isopeptidase activity http://purl.obolibrary.org/obo/GO_0070138 GO:0070139 biolink:MolecularActivity SUMO-specific endopeptidase activity Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO. Reactome:R-HSA-2990842|Reactome:R-HSA-2990840|Reactome:R-HSA-2993763 go-plus.json http://purl.obolibrary.org/obo/GO_0070139 GO:0070136 biolink:BiologicalProcess beta-1,2-oligomannoside biosynthetic process The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan. go-plus.json beta-1,2-oligomannoside anabolism|beta-1,2-oligomannoside synthesis|beta-1,2-oligomannoside formation|beta-1,2-oligomannoside biosynthesis http://purl.obolibrary.org/obo/GO_0070136 GO:0070137 biolink:MolecularActivity ubiquitin-like protein-specific endopeptidase activity Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO). go-plus.json small conjugating protein-specific endopeptidase activity http://purl.obolibrary.org/obo/GO_0070137 GO:0070134 biolink:BiologicalProcess positive regulation of mitochondrial translational initiation Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. go-plus.json positive regulation of mitochondrial translation initiation http://purl.obolibrary.org/obo/GO_0070134 GO:0070135 biolink:BiologicalProcess beta-1,2-oligomannoside metabolic process The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan. go-plus.json beta-1,2-oligomannoside metabolism http://purl.obolibrary.org/obo/GO_0070135 GO:0070132 biolink:BiologicalProcess regulation of mitochondrial translational initiation Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. go-plus.json regulation of mitochondrial translation initiation http://purl.obolibrary.org/obo/GO_0070132 GO:0070133 biolink:BiologicalProcess negative regulation of mitochondrial translational initiation Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. go-plus.json negative regulation of mitochondrial translation initiation http://purl.obolibrary.org/obo/GO_0070133 GO:0045185 biolink:BiologicalProcess maintenance of protein location Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. go-plus.json protein sequestering|protein retention|active protein retrieval|maintenance of protein localization http://purl.obolibrary.org/obo/GO_0045185 GO:0045186 biolink:BiologicalProcess zonula adherens assembly Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0045186 GO:0070120 biolink:BiologicalProcess ciliary neurotrophic factor-mediated signaling pathway A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CNTF-mediated signaling pathway|ciliary neurotrophic factor-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0070120 GO:0045183 biolink:MolecularActivity translation factor activity, non-nucleic acid binding A translation regulator activity that does not involve binding to nucleic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0045183 GO:0045184 biolink:BiologicalProcess establishment of protein localization The directed movement of a protein to a specific location. go-plus.json protein recruitment|protein positioning|establishment of protein localisation http://purl.obolibrary.org/obo/GO_0045184 GO:0045181 biolink:MolecularActivity glutamate synthase activity, NAD(P)H as acceptor Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+. go-plus.json glutamate synthase activity, NADH or NADPH as acceptor http://purl.obolibrary.org/obo/GO_0045181 GO:0045182 biolink:MolecularActivity translation regulator activity Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. go-plus.json translation factor activity http://purl.obolibrary.org/obo/GO_0045182 goslim_candida|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus GO:1901679 biolink:BiologicalProcess nucleotide transmembrane transport The directed movement of nucleotide across a membrane. go-plus.json nucleotide membrane transport http://purl.obolibrary.org/obo/GO_1901679 GO:0045180 biolink:CellularComponent basal cortex The region that lies just beneath the plasma membrane on the basal edge of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0045180 GO:1901677 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901677 GO:1901678 biolink:BiologicalProcess iron coordination entity transport The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901678 GO:1901675 biolink:BiologicalProcess negative regulation of histone H3-K27 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation. go-plus.json down-regulation of histone H3 acetylation at K27|negative regulation of histone H3 acetylation at K27|down regulation of histone H3-K27 acetylation|inhibition of histone H3-K27 acetylation|down regulation of histone H3K27 acetylation|downregulation of histone H3K27 acetylation|inhibition of histone H3 acetylation at K27|negative regulation of histone H3K27 acetylation|down-regulation of histone H3K27 acetylation|down regulation of histone H3 acetylation at K27|down-regulation of histone H3-K27 acetylation|downregulation of histone H3 acetylation at K27|inhibition of histone H3K27 acetylation|downregulation of histone H3-K27 acetylation http://purl.obolibrary.org/obo/GO_1901675 GO:1901676 biolink:BiologicalProcess positive regulation of histone H3-K27 acetylation Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation. go-plus.json activation of histone H3 acetylation at K27|upregulation of histone H3K27 acetylation|upregulation of histone H3-K27 acetylation|up-regulation of histone H3 acetylation at K27|up regulation of histone H3K27 acetylation|positive regulation of histone H3K27 acetylation|up-regulation of histone H3-K27 acetylation|activation of histone H3-K27 acetylation|upregulation of histone H3 acetylation at K27|activation of histone H3K27 acetylation|up-regulation of histone H3K27 acetylation|up regulation of histone H3-K27 acetylation|up regulation of histone H3 acetylation at K27|positive regulation of histone H3 acetylation at K27 http://purl.obolibrary.org/obo/GO_1901676 GO:0045189 biolink:BiologicalProcess obsolete connective tissue growth factor biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta. go-plus.json connective tissue growth factor synthesis|connective tissue growth factor formation|connective tissue growth factor biosynthesis|CTGF biosynthesis|connective tissue growth factor anabolism http://purl.obolibrary.org/obo/GO_0045189 GO:1901673 biolink:BiologicalProcess regulation of mitotic spindle assembly Any process that modulates the frequency, rate or extent of mitotic spindle assembly. go-plus.json regulation of spindle assembly involved in mitosis http://purl.obolibrary.org/obo/GO_1901673 GO:1901674 biolink:BiologicalProcess regulation of histone H3-K27 acetylation Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation. go-plus.json regulation of histone H3K27 acetylation|regulation of histone H3 acetylation at K27 http://purl.obolibrary.org/obo/GO_1901674 GO:1901671 biolink:BiologicalProcess positive regulation of superoxide dismutase activity Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity. go-plus.json positive regulation of nickel superoxide oxidoreductase|up regulation of erythrocuprein|up regulation of Cu,Zn-SOD|up-regulation of cuprein|up-regulation of SODS|up regulation of SOD|activation of SOD-4|activation of zinc superoxide oxidoreductase|positive regulation of manganese superoxide oxidoreductase|positive regulation of Cu,Zn-SOD|up regulation of nickel superoxide oxidoreductase|activation of SOD-3|positive regulation of iron superoxide oxidoreductase|positive regulation of ferrisuperoxide dismutase activity|activation of SOD-2|activation of copper, zinc superoxide dismutase activity|activation of hepatocuprein|activation of Cu-Zn superoxide dismutase activity|positive regulation of SOD|up regulation of iron superoxide oxidoreductase|upregulation of manganese superoxide dismutase activity|activation of SOD-1|up-regulation of nickel superoxide dismutase activity|up regulation of cytocuprein|up regulation of superoxide dismutase II|upregulation of superoxide:superoxide oxidoreductase activity|up regulation of ferrisuperoxide dismutase activity|upregulation of SODF|up-regulation of Mn, Fe superoxide dismutase|positive regulation of superoxide dismutase II|positive regulation of cytocuprein|activation of manganese superoxide oxidoreductase|up-regulation of iron superoxide dismutase activity|positive regulation of zinc superoxide oxidoreductase|up-regulation of SOD-4|activation of Cu,Zn-SOD|upregulation of superoxide dismutase activity|activation of SODS|upregulation of Mn-SOD|activation of SOD|up-regulation of SOD-3|upregulation of hemocuprein|positive regulation of copper, zinc superoxide dismutase activity|up-regulation of superoxide dismutase I|up regulation of zinc superoxide oxidoreductase|up-regulation of Cu-Zn superoxide dismutase activity|upregulation of cuprein|up-regulation of SOD-2|up-regulation of hepatocuprein|upregulation of Fe-SOD|up-regulation of SOD-1|up regulation of copper, zinc superoxide dismutase activity|activation of nickel superoxide dismutase activity|upregulation of erythrocuprein|activation of cytocuprein|activation of superoxide dismutase II|up-regulation of manganese superoxide oxidoreductase|activation of iron superoxide dismutase activity|upregulation of nickel superoxide oxidoreductase|positive regulation of SODS|up-regulation of Cu,Zn-SOD|upregulation of iron superoxide oxidoreductase|up-regulation of SODF|up-regulation of SOD|activation of superoxide dismutase I|up regulation of manganese superoxide dismutase activity|upregulation of Mn, Fe superoxide dismutase|up regulation of SODS|positive regulation of nickel superoxide dismutase activity|up regulation of superoxide:superoxide oxidoreductase activity|upregulation of ferrisuperoxide dismutase activity|up-regulation of Mn-SOD|positive regulation of manganese superoxide dismutase activity|upregulation of SOD-4|up regulation of superoxide dismutase activity|upregulation of SOD-3|up-regulation of cytocuprein|positive regulation of superoxide:superoxide oxidoreductase activity|positive regulation of iron superoxide dismutase activity|up regulation of nickel superoxide dismutase activity|up-regulation of superoxide dismutase II|up regulation of hemocuprein|activation of superoxide dismutase activity|upregulation of SOD-2|up-regulation of Fe-SOD|upregulation of hepatocuprein|upregulation of zinc superoxide oxidoreductase|upregulation of Cu-Zn superoxide dismutase activity|upregulation of SOD-1|up regulation of iron superoxide dismutase activity|up-regulation of erythrocuprein|up regulation of cuprein|positive regulation of superoxide dismutase I|positive regulation of hemocuprein|activation of SODF|upregulation of copper, zinc superoxide dismutase activity|positive regulation of cuprein|activation of manganese superoxide dismutase activity|upregulation of manganese superoxide oxidoreductase|up-regulation of nickel superoxide oxidoreductase|up regulation of superoxide dismutase I|activation of Mn-SOD|upregulation of Cu,Zn-SOD|activation of superoxide:superoxide oxidoreductase activity|upregulation of SOD|up-regulation of iron superoxide oxidoreductase|up regulation of Mn, Fe superoxide dismutase|upregulation of SODS|activation of Fe-SOD|up-regulation of ferrisuperoxide dismutase activity|positive regulation of SODF|activation of erythrocuprein|activation of hemocuprein|upregulation of superoxide dismutase II|positive regulation of Mn, Fe superoxide dismutase|upregulation of cytocuprein|up regulation of SOD-4|activation of cuprein|activation of nickel superoxide oxidoreductase|positive regulation of Mn-SOD|up-regulation of manganese superoxide dismutase activity|upregulation of nickel superoxide dismutase activity|up regulation of SOD-3|up-regulation of zinc superoxide oxidoreductase|up regulation of SODF|up-regulation of superoxide:superoxide oxidoreductase activity|up regulation of Cu-Zn superoxide dismutase activity|up regulation of SOD-2|positive regulation of SOD-4|up regulation of hepatocuprein|upregulation of iron superoxide dismutase activity|positive regulation of Fe-SOD|activation of iron superoxide oxidoreductase|up regulation of Mn-SOD|up regulation of SOD-1|positive regulation of SOD-3|up-regulation of copper, zinc superoxide dismutase activity|activation of ferrisuperoxide dismutase activity|positive regulation of erythrocuprein|up-regulation of superoxide dismutase activity|positive regulation of hepatocuprein|positive regulation of SOD-2|positive regulation of Cu-Zn superoxide dismutase activity|activation of Mn, Fe superoxide dismutase|upregulation of superoxide dismutase I|up-regulation of hemocuprein|up regulation of manganese superoxide oxidoreductase|positive regulation of SOD-1|up regulation of Fe-SOD http://purl.obolibrary.org/obo/GO_1901671 GO:0045187 biolink:BiologicalProcess regulation of circadian sleep/wake cycle, sleep Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. go-plus.json regulation of sleep http://purl.obolibrary.org/obo/GO_0045187 GO:1901672 biolink:BiologicalProcess positive regulation of systemic acquired resistance Any process that activates or increases the frequency, rate or extent of systemic acquired resistance. go-plus.json up regulation of systemic acquired resistance|upregulation of salicylic acid-dependent systemic resistance|upregulation of systemic acquired resistance|up-regulation of salicylic acid-dependent systemic resistance|activation of salicylic acid-dependent systemic resistance|up-regulation of systemic acquired resistance|activation of systemic acquired resistance|positive regulation of salicylic acid-dependent systemic resistance|up regulation of salicylic acid-dependent systemic resistance http://purl.obolibrary.org/obo/GO_1901672 GO:0045188 biolink:BiologicalProcess regulation of circadian sleep/wake cycle, non-REM sleep Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. go-plus.json regulation of non-REM sleep http://purl.obolibrary.org/obo/GO_0045188 GO:1901680 biolink:MolecularActivity sulfur-containing amino acid secondary active transmembrane transporter activity Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json http://purl.obolibrary.org/obo/GO_1901680 GO:1901681 biolink:MolecularActivity sulfur compound binding Binding to a sulfur compound. go-plus.json sulfur molecular entity binding http://purl.obolibrary.org/obo/GO_1901681 GO:0070129 biolink:BiologicalProcess regulation of mitochondrial translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. go-plus.json regulation of mitochondrial protein anabolism|regulation of mitochondrial protein biosynthesis|regulation of mitochondrial protein synthesis|regulation of mitochondrial protein formation http://purl.obolibrary.org/obo/GO_0070129 GO:0070127 biolink:BiologicalProcess tRNA aminoacylation for mitochondrial protein translation The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0070127 GO:0070128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070128 GO:0070125 biolink:BiologicalProcess mitochondrial translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. go-plus.json mitochondrial translation elongation http://purl.obolibrary.org/obo/GO_0070125 GO:0070126 biolink:BiologicalProcess mitochondrial translational termination The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). go-plus.json mitochondrial translation termination http://purl.obolibrary.org/obo/GO_0070126 GO:0070123 biolink:MolecularActivity transforming growth factor beta receptor activity, type III Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors. go-plus.json type III TGF-beta receptor activity|type III TGFbeta receptor activity|betaglycan|transforming growth factor beta ligand binding to type III receptor|type III transforming growth factor beta receptor activity|endoglin http://purl.obolibrary.org/obo/GO_0070123 GO:0070124 biolink:BiologicalProcess mitochondrial translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. go-plus.json mitochondrial translation initiation http://purl.obolibrary.org/obo/GO_0070124 GO:0070121 biolink:BiologicalProcess Kupffer's vesicle development The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. go-plus.json KV development http://purl.obolibrary.org/obo/GO_0070121 GO:0070122 biolink:MolecularActivity isopeptidase activity Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond). go-plus.json http://purl.obolibrary.org/obo/GO_0070122 GO:0060908 biolink:BiologicalProcess plasmid copy number maintenance The maintenance of the number of copies of extrachromosomal plasmid DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0060908 CHEBI:71596 biolink:ChemicalSubstance mycocyclosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71596 chebi_ph7_3 GO:0060909 biolink:BiologicalProcess regulation of DNA replication initiation involved in plasmid copy number maintenance Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_0060909 CHEBI:71598 biolink:ChemicalSubstance 3-oxo Delta(7)-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71598 SO:0002343 biolink:SequenceFeature cytosolic_rRNA Cytosolic rRNA is an RNA component of the small or large subunits of cytosolic ribosomes. go-plus.json cytosolic rRNA|cytosolic ribosomal RNA http://purl.obolibrary.org/obo/SO_0002343 CHEBI:71599 biolink:ChemicalSubstance pulcherriminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71599 GO:0035944 biolink:BiologicalProcess perforin production The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0035944 gocheck_do_not_annotate GO:0035945 biolink:BiologicalProcess mitochondrial ncRNA surveillance The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion. go-plus.json mitochondrial ncRNA quality control|mitochondrial aberrant ncRNA catabolic process|mitochondrial non-coding RNA surveillance http://purl.obolibrary.org/obo/GO_0035945 GO:0035946 biolink:BiologicalProcess mitochondrial mRNA surveillance The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion. go-plus.json mitochondrial aberrant RNA catabolic process|mitochondrial mRNA quality control|mitochondrial messenger RNA surveillance http://purl.obolibrary.org/obo/GO_0035946 GO:0035947 biolink:BiologicalProcess obsolete regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter. go-plus.json regulation of glucose biosynthetic process by regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035947 GO:0035948 biolink:BiologicalProcess obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of glucose biosynthetic process by up regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by up regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by stimulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by activation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up-regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by upregulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by upregulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by up-regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by upregulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035948 GO:0035949 biolink:BiologicalProcess obsolete positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of glucose biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down-regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by inhibition of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthetic process by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthesis by down regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by down regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035949 GO:0035940 biolink:BiologicalProcess obsolete negative regulation of peptidase activity in other organism OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism. go-plus.json downregulation of peptidase activity in other organism|negative regulation of protease activity in other organism|down-regulation of protease activity in other organism|down regulation of peptidase activity in other organism|inhibition of protease activity in other organism http://purl.obolibrary.org/obo/GO_0035940 GO:0035941 biolink:BiologicalProcess androstenedione secretion The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system. go-plus.json androst-4-ene-3,17-dione secretion http://purl.obolibrary.org/obo/GO_0035941 GO:0035942 biolink:BiologicalProcess dehydroepiandrosterone secretion The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system. go-plus.json DHEA secretion|dehydroisoandrosterone secretion|3beta-hydroxyandrost-5-en-17-one secretion http://purl.obolibrary.org/obo/GO_0035942 GO:0060910 biolink:BiologicalProcess negative regulation of DNA replication initiation involved in plasmid copy number maintenance Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_0060910 GO:0035943 biolink:BiologicalProcess estrone secretion The regulated release of estrone into the circulatory system. go-plus.json folliculin secretion|3-hydroxy-1,3,5(10)-estratrien-17-one secretion http://purl.obolibrary.org/obo/GO_0035943 GO:0060911 biolink:BiologicalProcess cardiac cell fate commitment The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system. go-plus.json cardiocyte cell fate commitment http://purl.obolibrary.org/obo/GO_0060911 GO:0060912 biolink:BiologicalProcess cardiac cell fate specification The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. go-plus.json cardiocyte cell fate specification http://purl.obolibrary.org/obo/GO_0060912 GO:0060913 biolink:BiologicalProcess cardiac cell fate determination The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. go-plus.json cardiocyte cell fate determination http://purl.obolibrary.org/obo/GO_0060913 CHEBI:71590 biolink:ChemicalSubstance (3E,5Z)-tetradecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71590 chebi_ph7_3 GO:0060914 biolink:BiologicalProcess heart formation The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. go-plus.json cardiogenesis http://purl.obolibrary.org/obo/GO_0060914 CHEBI:71591 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71591 GO:0060915 biolink:BiologicalProcess mesenchymal cell differentiation involved in lung development The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. go-plus.json http://purl.obolibrary.org/obo/GO_0060915 CHEBI:71592 biolink:ChemicalSubstance anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] go-plus.json http://purl.obolibrary.org/obo/CHEBI_71592 GO:0060916 biolink:BiologicalProcess mesenchymal cell proliferation involved in lung development The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json http://purl.obolibrary.org/obo/GO_0060916 GO:0060917 biolink:BiologicalProcess regulation of (1->6)-beta-D-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. go-plus.json regulation of 1,6-beta-glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0060917 GO:0060918 biolink:BiologicalProcess auxin transport The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0060918 GO:0035933 biolink:BiologicalProcess glucocorticoid secretion The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. go-plus.json http://purl.obolibrary.org/obo/GO_0035933 GO:0035934 biolink:BiologicalProcess corticosterone secretion The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. go-plus.json http://purl.obolibrary.org/obo/GO_0035934 GO:0035935 biolink:BiologicalProcess androgen secretion The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0035935 GO:0035936 biolink:BiologicalProcess testosterone secretion The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5. go-plus.json http://purl.obolibrary.org/obo/GO_0035936 GO:0035937 biolink:BiologicalProcess estrogen secretion The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals. go-plus.json oestrogen secretion http://purl.obolibrary.org/obo/GO_0035937 GO:0035938 biolink:BiologicalProcess estradiol secretion The regulated release of estradiol into the circulatory system. go-plus.json oestradiol secretion http://purl.obolibrary.org/obo/GO_0035938 GO:0035939 biolink:MolecularActivity microsatellite binding Binding to a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem. go-plus.json variable number tandem repeat binding|microsatellite DNA binding|VNTR binding http://purl.obolibrary.org/obo/GO_0035939 GO:0035930 biolink:BiologicalProcess corticosteroid hormone secretion The regulated release of any corticosteroid hormone into the circulatory system. go-plus.json corticosteroid secretion http://purl.obolibrary.org/obo/GO_0035930 GO:0035931 biolink:BiologicalProcess mineralocorticoid secretion The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0035931 GO:0035932 biolink:BiologicalProcess aldosterone secretion The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0035932 GO:0060900 biolink:BiologicalProcess embryonic camera-type eye formation The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. go-plus.json http://purl.obolibrary.org/obo/GO_0060900 GO:0060901 biolink:BiologicalProcess regulation of hair cycle by canonical Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle. go-plus.json regulation of hair cycle by Wnt receptor signaling pathway through beta-catenin|regulation of hair cycle by canonical Wnt receptor signalling pathway|regulation of hair cycle by canonical Wnt receptor signaling pathway|regulation of hair cycle by canonical Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_0060901 GO:0060902 biolink:BiologicalProcess regulation of hair cycle by BMP signaling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle. go-plus.json regulation of hair cycle by BMP signalling pathway http://purl.obolibrary.org/obo/GO_0060902 GO:0060903 biolink:BiologicalProcess positive regulation of meiosis I Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060903 GO:0060904 biolink:BiologicalProcess regulation of protein folding in endoplasmic reticulum Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). go-plus.json http://purl.obolibrary.org/obo/GO_0060904 GO:0060905 biolink:BiologicalProcess regulation of induction of conjugation upon nitrogen starvation Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0060905 GO:0060906 biolink:BiologicalProcess negative regulation of heterochromatin assembly by small RNA Any process that decreases the frequency, rate or extent of heterochromatin assembly by small RNA. go-plus.json negative regulation of chromatin silencing by small RNA|negative regulation of RNAi-mediated heterochromatin assembly http://purl.obolibrary.org/obo/GO_0060906 GO:0060907 biolink:BiologicalProcess positive regulation of macrophage cytokine production Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0060907 GO:0035922 biolink:BiologicalProcess foramen ovale closure The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow. go-plus.json foramen ovale of heart closure http://purl.obolibrary.org/obo/GO_0035922 GO:0035923 biolink:MolecularActivity flurbiprofen binding Binding to flurbiprofen. go-plus.json 2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid binding http://purl.obolibrary.org/obo/GO_0035923 GO:0035924 biolink:BiologicalProcess cellular response to vascular endothelial growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus. go-plus.json cellular response to VEGFB|cellular response to VEGFA|cellular response to vascular endothelial growth factor|cellular response to VEGF http://purl.obolibrary.org/obo/GO_0035924 GO:0035925 biolink:MolecularActivity mRNA 3'-UTR AU-rich region binding Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs. go-plus.json mRNA 3'-UTR adenylate/uridylate-rich element binding|adenylate/uridylate-rich element binding|ARE binding|AU-rich element binding http://purl.obolibrary.org/obo/GO_0035925 GO:0035926 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035926 GO:0035927 biolink:BiologicalProcess RNA import into mitochondrion The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix. go-plus.json nuclear-encoded RNA import into mitochondrion|cytoplasmic RNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0035927 GO:0035928 biolink:BiologicalProcess rRNA import into mitochondrion The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix. go-plus.json nuclear-encoded rRNA import into mitochondrion|cytoplasmic rRNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0035928 GO:0035929 biolink:BiologicalProcess steroid hormone secretion The regulated release of any steroid that acts as a hormone into the circulatory system. go-plus.json http://purl.obolibrary.org/obo/GO_0035929 NCBITaxon:9254 biolink:OrganismalEntity Prototheria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9254 NCBITaxon:9255 biolink:OrganismalEntity Monotremata go-plus.json egg-laying mammals|monotremes http://purl.obolibrary.org/obo/NCBITaxon_9255 NCBITaxon:9256 biolink:OrganismalEntity Ornithorhynchidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9256 NCBITaxon:9257 biolink:OrganismalEntity Ornithorhynchus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9257 GO:0060930 biolink:BiologicalProcess sinoatrial node cell fate commitment The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node. go-plus.json SA node cell commitment|sinus node cell commitment|SAN cell commitment http://purl.obolibrary.org/obo/GO_0060930 NCBITaxon:9258 biolink:OrganismalEntity Ornithorhynchus anatinus go-plus.json platypus|duckbill platypus|Platypus anatinus|duck-billed platypus http://purl.obolibrary.org/obo/NCBITaxon_9258 GO:0060931 biolink:BiologicalProcess sinoatrial node cell development The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. go-plus.json SA node cell development|SAN cell development|sinus node cell development http://purl.obolibrary.org/obo/GO_0060931 GO:0035920 biolink:BiologicalProcess negative regulation of high voltage-gated calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded. go-plus.json negative regulation of high voltage-dependent calcium channel activity in other organism|inhibition of high voltage-gated calcium channel activity in other organism|negative regulation of high voltage gated calcium channel activity in other organism|downregulation of high voltage-gated calcium channel activity in other organism|down-regulation of high voltage-gated calcium channel activity in other organism http://purl.obolibrary.org/obo/GO_0035920 GO:0035921 biolink:BiologicalProcess desmosome disassembly The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. go-plus.json desmosome dissociation http://purl.obolibrary.org/obo/GO_0035921 GO:0060932 biolink:BiologicalProcess His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. go-plus.json http://purl.obolibrary.org/obo/GO_0060932 GO:0060933 biolink:BiologicalProcess His-Purkinje system cell development The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. go-plus.json http://purl.obolibrary.org/obo/GO_0060933 GO:0060934 biolink:BiologicalProcess His-Purkinje system cell fate commitment The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. go-plus.json http://purl.obolibrary.org/obo/GO_0060934 GO:0060935 biolink:BiologicalProcess cardiac fibroblast cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060935 GO:0060936 biolink:BiologicalProcess cardiac fibroblast cell development The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060936 GO:0060937 biolink:BiologicalProcess cardiac fibroblast cell fate commitment The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060937 GO:0060938 biolink:BiologicalProcess epicardium-derived cardiac fibroblast cell differentiation The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060938 GO:0060939 biolink:BiologicalProcess epicardium-derived cardiac fibroblast cell development The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060939 GO:0035919 biolink:BiologicalProcess negative regulation of low voltage-gated calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded. go-plus.json down-regulation of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage-dependent calcium channel activity in other organism|downregulation of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage gated calcium channel activity in other organism|inhibition of low voltage-gated calcium channel activity in other organism http://purl.obolibrary.org/obo/GO_0035919 GO:0060919 biolink:BiologicalProcess auxin influx The process involved in the transport of auxin into the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060919 GO:0045303 biolink:MolecularActivity diaminobutyrate-2-oxoglutarate transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate. RHEA:11160|KEGG_REACTION:R06977|MetaCyc:R101-RXN|EC:2.6.1.76 go-plus.json diaminobutyrate--2-oxoglutarate aminotransferase activity|diaminobutyrate transaminase activity|DABA aminotransferase activity|diaminibutyric acid aminotransferase activity|L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity|L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity|EctB|L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity|2,4-diaminobutyrate 4-aminotransferase activity|DAB aminotransferase activity http://purl.obolibrary.org/obo/GO_0045303 GO:0035911 biolink:BiologicalProcess descending aorta morphogenesis The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035911 GO:0045304 biolink:BiologicalProcess regulation of establishment of competence for transformation Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome. go-plus.json regulator of establishment of competence for transformation activity http://purl.obolibrary.org/obo/GO_0045304 CHEBI:141610 biolink:ChemicalSubstance 3-hydroxy-D-kynurenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_141610 chebi_ph7_3 GO:0035912 biolink:BiologicalProcess dorsal aorta morphogenesis The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035912 GO:0045301 biolink:MolecularActivity tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin. go-plus.json 2-methylthio-cis-ribozeatin hydroxylase activity|tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity|tRNA-(ms2io6A)-hydroxylase activity http://purl.obolibrary.org/obo/GO_0045301 GO:0035913 biolink:BiologicalProcess ventral aorta morphogenesis The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035913 GO:0045302 biolink:MolecularActivity choloylglycine hydrolase activity Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine. MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN|RHEA:19353|EC:3.5.1.24 go-plus.json choloyltaurine hydrolase activity|bile salt hydrolase activity|glycocholase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0045302 GO:0035914 biolink:BiologicalProcess skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0035914 GO:0035915 biolink:BiologicalProcess pore formation in membrane of other organism The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism. go-plus.json pore-forming toxin activity|pore formation in other organism|pore complex biogenesis in other organism|pore biosynthesis in other organism|pore complex assembly in other organism http://purl.obolibrary.org/obo/GO_0035915 GO:0035916 biolink:BiologicalProcess modulation of calcium channel activity in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0035916 GO:0045300 biolink:MolecularActivity acyl-[acyl-carrier-protein] desaturase activity Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin. MetaCyc:1.14.19.2-RXN|EC:1.14.19.2|MetaCyc:PWY-5147 go-plus.json acyl-acyl-carrier-protein desaturase activity|stearyl-ACP desaturase activity|stearyl acyl carrier protein desaturase activity|acyl-[acyl-carrier protein] desaturase activity|acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0045300 GO:0035917 biolink:BiologicalProcess negative regulation of calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism. go-plus.json down-regulation of calcium channel activity in other organism|downregulation of calcium channel activity in other organism|inhibition of calcium channel activity in other organism http://purl.obolibrary.org/obo/GO_0035917 GO:0035918 biolink:BiologicalProcess negative regulation of voltage-gated calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json negative regulation of voltage gated calcium channel activity in other organism|inhibition of voltage-gated calcium channel activity in other organism|negative regulation of voltage-sensitive calcium channel activity in other organism|down-regulation of voltage-gated calcium channel activity in other organism|negative regulation of voltage-dependent calcium channel activity in other organism|downregulation of voltage-gated calcium channel activity in other organism http://purl.obolibrary.org/obo/GO_0035918 CHEBI:141617 biolink:ChemicalSubstance hapalindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_141617 NCBITaxon:9265 biolink:OrganismalEntity Didelphidae go-plus.json opossums|American opossums http://purl.obolibrary.org/obo/NCBITaxon_9265 GO:0045309 biolink:MolecularActivity protein phosphorylated amino acid binding Binding to a phosphorylated amino acid residue within a protein. go-plus.json phosphoprotein amino acid binding http://purl.obolibrary.org/obo/GO_0045309 CHEBI:141616 biolink:ChemicalSubstance hapalindole-type alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_141616 GO:0045307 biolink:MolecularActivity obsolete activator of the establishment of competence for transformation activity OBSOLETE. Activates the establishment of competence for transformation. go-plus.json activator of the establishment of competence for transformation activity http://purl.obolibrary.org/obo/GO_0045307 GO:0045308 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045308 GO:0045305 biolink:MolecularActivity obsolete regulator of establishment of competence for transformation activity OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation. go-plus.json regulator of establishment of competence for transformation activity http://purl.obolibrary.org/obo/GO_0045305 GO:0060920 biolink:BiologicalProcess cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. go-plus.json pacemaker cell differentiation http://purl.obolibrary.org/obo/GO_0060920 GO:0060921 biolink:BiologicalProcess sinoatrial node cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. go-plus.json sinus node cell differentiation|SA node cell differentiation|SAN cell differentiation http://purl.obolibrary.org/obo/GO_0060921 GO:0035910 biolink:BiologicalProcess ascending aorta morphogenesis The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035910 GO:0045306 biolink:MolecularActivity obsolete inhibitor of the establishment of competence for transformation activity OBSOLETE. Inhibits the establishment of competence for transformation. go-plus.json inhibitor of the establishment of competence for transformation activity http://purl.obolibrary.org/obo/GO_0045306 GO:0060922 biolink:BiologicalProcess atrioventricular node cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. go-plus.json AV node cell differentiation http://purl.obolibrary.org/obo/GO_0060922 GO:0060923 biolink:BiologicalProcess cardiac muscle cell fate commitment The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. go-plus.json cardiomyocyte cell fate commitment|heart muscle cell fate commitment http://purl.obolibrary.org/obo/GO_0060923 GO:0060924 biolink:BiologicalProcess atrial cardiac muscle cell fate commitment The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. go-plus.json atrial heart muscle cell fate commitment|atrial cardiomyocyte cell fate commitment http://purl.obolibrary.org/obo/GO_0060924 GO:0060925 biolink:BiologicalProcess ventricular cardiac muscle cell fate commitment The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. go-plus.json ventricular cardiomyocyte cell fate commitment|ventricular heart muscle cell fate commitment http://purl.obolibrary.org/obo/GO_0060925 GO:0060926 biolink:BiologicalProcess cardiac pacemaker cell development The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. go-plus.json pacemaker cell development http://purl.obolibrary.org/obo/GO_0060926 GO:0060927 biolink:BiologicalProcess cardiac pacemaker cell fate commitment The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. go-plus.json pacemaker cell fate commitment http://purl.obolibrary.org/obo/GO_0060927 CHEBI:141619 biolink:ChemicalSubstance fischerindole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_141619 GO:0060928 biolink:BiologicalProcess atrioventricular node cell development The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. go-plus.json AV node cell development http://purl.obolibrary.org/obo/GO_0060928 GO:0060929 biolink:BiologicalProcess atrioventricular node cell fate commitment The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells. go-plus.json AV node cell fate commitment http://purl.obolibrary.org/obo/GO_0060929 NCBITaxon:9263 biolink:OrganismalEntity Metatheria go-plus.json marsupials|marsupials|Marsupialia http://purl.obolibrary.org/obo/NCBITaxon_9263 GO:0035908 biolink:BiologicalProcess ventral aorta development The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035908 GO:0035909 biolink:BiologicalProcess aorta morphogenesis The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0035909 UBERON:0003528 biolink:AnatomicalEntity brain gray matter A gray matter that is part of a brain [Automatically generated definition]. go-plus.json gray matter of brain|grey matter of brain|grey substance of brain|brain grey substance|brain grey matter http://purl.obolibrary.org/obo/UBERON_0003528 UBERON:0003529 biolink:AnatomicalEntity respiratory system lymphatic vessel endothelium An lymphatic vessel endothelium that is part of a respiratory system [Automatically generated definition]. go-plus.json apparatus respiratorius lymph vessel endothelium|apparatus respiratorius endothelium of lymph vessel|lymphatic vessel endothelium of respiratory system|lymphatic vessel endothelium of apparatus respiratorius|respiratory system lymph vessel endothelium|apparatus respiratorius lymphatic vessel endothelium|endothelium of lymph vessel of respiratory system|lymph vessel endothelium of apparatus respiratorius|lymph vessel endothelium of respiratory system|respiratory system endothelium of lymph vessel|respiratory system lymphatic vessel endothelium|endothelium of lymph vessel of apparatus respiratorius http://purl.obolibrary.org/obo/UBERON_0003529 UBERON:0003526 biolink:AnatomicalEntity respiratory system capillary A capillary that is part of a respiratory system [Automatically generated definition]. go-plus.json capillary vessel of respiratory system|respiratory system blood capillary|capillary vessel of apparatus respiratorius|apparatus respiratorius capillary|apparatus respiratorius capillary vessel|blood capillary of apparatus respiratorius|apparatus respiratorius blood capillary|capillary of apparatus respiratorius|respiratory system capillary vessel|capillary of respiratory system|blood capillary of respiratory system http://purl.obolibrary.org/obo/UBERON_0003526 UBERON:0003527 biolink:AnatomicalEntity kidney capillary A capillary that is part of a kidney [Automatically generated definition]. go-plus.json renal capillary|capillary of kidney|blood capillary of kidney|capillary vessel of kidney|kidney capillary vessel|kidney blood capillary http://purl.obolibrary.org/obo/UBERON_0003527 GO:0045314 biolink:BiologicalProcess regulation of compound eye photoreceptor development Any process that modulates the frequency, rate or extent of compound eye photoreceptor development. go-plus.json regulation of eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045314 GO:0035900 biolink:BiologicalProcess response to isolation stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species. go-plus.json response to social isolation http://purl.obolibrary.org/obo/GO_0035900 GO:0045315 biolink:BiologicalProcess positive regulation of compound eye photoreceptor development Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development. go-plus.json up regulation of eye photoreceptor development|positive regulation of eye photoreceptor development|activation of eye photoreceptor development|stimulation of eye photoreceptor development|up-regulation of eye photoreceptor development|upregulation of eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045315 GO:0035901 biolink:BiologicalProcess cellular response to isolation stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species. go-plus.json cellular response to social isolation http://purl.obolibrary.org/obo/GO_0035901 GO:0045312 biolink:BiologicalProcess nor-spermidine biosynthetic process The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. go-plus.json nor-spermidine anabolism|nor-spermidine synthesis|nor-spermidine formation|nor-spermidine biosynthesis http://purl.obolibrary.org/obo/GO_0045312 GO:0035902 biolink:BiologicalProcess response to immobilization stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile. go-plus.json response to restraint stress|response to immobilisation stress http://purl.obolibrary.org/obo/GO_0035902 GO:0045313 biolink:BiologicalProcess rhabdomere membrane biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0045313 GO:0035903 biolink:BiologicalProcess cellular response to immobilization stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile. go-plus.json cellular response to immobilisation stress|cellular response to restraint stress http://purl.obolibrary.org/obo/GO_0035903 GO:0035904 biolink:BiologicalProcess aorta development The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0035904 GO:0045310 biolink:MolecularActivity obsolete phosphoserine/phosphothreonine binding OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein. go-plus.json phosphoserine/phosphothreonine binding http://purl.obolibrary.org/obo/GO_0045310 GO:0045311 biolink:BiologicalProcess invasive growth in response to pheromone The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0045311 GO:0035905 biolink:BiologicalProcess ascending aorta development The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035905 GO:0035906 biolink:BiologicalProcess descending aorta development The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035906 GO:0035907 biolink:BiologicalProcess dorsal aorta development The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. go-plus.json http://purl.obolibrary.org/obo/GO_0035907 GO:0060950 biolink:BiologicalProcess cardiac glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060950 GO:0060951 biolink:BiologicalProcess neural crest-derived cardiac glial cell differentiation The process in which a neural crest cell acquires the specialized features of a glial cell of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060951 GO:0045318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045318 GO:0060952 biolink:BiologicalProcess cardiac glial cell development The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060952 GO:0045319 biolink:BiologicalProcess obsolete SRP-independent cotranslational protein-membrane targeting, translocation OBSOLETE. The process during cotranslational membrane targeting wherein proteins move across a membrane. This process is independent of SRP and signal recognition. go-plus.json SRP-independent cotranslational membrane targeting, translocation|SRP-independent cotranslational protein-membrane targeting, translocation http://purl.obolibrary.org/obo/GO_0045319 GO:0060953 biolink:BiologicalProcess cardiac glial cell fate commitment The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060953 GO:0045316 biolink:BiologicalProcess negative regulation of compound eye photoreceptor development Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development. go-plus.json negative regulation of eye photoreceptor development|down-regulation of eye photoreceptor development|inhibition of eye photoreceptor development|down regulation of eye photoreceptor development|downregulation of eye photoreceptor development http://purl.obolibrary.org/obo/GO_0045316 GO:0060954 biolink:BiologicalProcess neural crest-derived cardiac glial cell development The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060954 GO:0045317 biolink:BiologicalProcess equator specification The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves. go-plus.json http://purl.obolibrary.org/obo/GO_0045317 GO:0060955 biolink:BiologicalProcess neural crest-derived cardiac glial cell fate commitment The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060955 UBERON:0003535 biolink:AnatomicalEntity vagus X nerve trunk A nerve trunk that is part of a vagus nerve. go-plus.json vagal X nerve trunk|vagus neural trunk|vagus nerve trunk|trunk of vagal nerve|trunk of vagus nerve|vagal nerve trunk http://purl.obolibrary.org/obo/UBERON_0003535 GO:0060956 biolink:BiologicalProcess endocardial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. go-plus.json http://purl.obolibrary.org/obo/GO_0060956 UBERON:0003533 biolink:AnatomicalEntity manual digit skin A zone of skin that is part of a finger [Automatically generated definition]. go-plus.json skin of hand digit|hand digit skin|skin of digit of hand|skin of digitus manus|skin of digit of terminal segment of free upper limb|digitus manus skin|fore limb digit skin|digit of hand skin|finger skin|skin of terminal segment of free upper limb digit|skin of finger|digit of terminal segment of free upper limb skin|hand digit skin|terminal segment of free upper limb digit skin http://purl.obolibrary.org/obo/UBERON_0003533 GO:0060957 biolink:BiologicalProcess endocardial cell fate commitment The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060957 GO:0060958 biolink:BiologicalProcess endocardial cell development The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060958 UBERON:0003534 biolink:AnatomicalEntity tail skin A zone of skin that is part of a tail [Automatically generated definition]. go-plus.json skin of post-vent region|skin of tail|post-vent region skin http://purl.obolibrary.org/obo/UBERON_0003534 GO:0060959 biolink:BiologicalProcess cardiac neuron development The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. go-plus.json heart neuron development http://purl.obolibrary.org/obo/GO_0060959 UBERON:0003531 biolink:AnatomicalEntity forelimb skin A zone of skin that is part of a forelimb [Automatically generated definition]. go-plus.json wing skin|skin of upper limb|skin of forelimb|skin of fore limb|upper limb skin|fore limb skin|anteriormost limb skin http://purl.obolibrary.org/obo/UBERON_0003531 UBERON:0003532 biolink:AnatomicalEntity hindlimb skin A zone of skin that is part of a hindlimb [Automatically generated definition]. go-plus.json hind limb skin|skin of lower limb|skin of hind limb|skin of lower extremity|skin of hindlimb|lower limb skin http://purl.obolibrary.org/obo/UBERON_0003532 UBERON:0003530 biolink:AnatomicalEntity pedal digit skin A zone of skin that is part of a toe [Automatically generated definition]. go-plus.json foot digit skin|skin of foot digit|skin of digitus pedis|skin of digit of foot|skin of digit of terminal segment of free lower limb|digit of foot skin|digitus pedis skin|hind limb digit skin|skin of terminal segment of free lower limb digit|toe skin|foot digit skin|digit of terminal segment of free lower limb skin|skin of toe|terminal segment of free lower limb digit skin http://purl.obolibrary.org/obo/UBERON_0003530 UBERON:0003519 biolink:AnatomicalEntity thoracic cavity blood vessel A blood vessel that is part of a thoracic cavity [Automatically generated definition]. go-plus.json chest cavity blood vessel|blood vessel of thoracic cavity|blood vessel of cavity of chest|blood vessel of pectoral cavity|pectoral cavity blood vessel|cavity of chest blood vessel|blood vessel of chest cavity|blood vessel of cavity of thorax|cavity of thorax blood vessel http://purl.obolibrary.org/obo/UBERON_0003519 UBERON:0003517 biolink:AnatomicalEntity kidney blood vessel A blood vessel that is part of a kidney [Automatically generated definition]. go-plus.json blood vessel of kidney|renal blood vessel http://purl.obolibrary.org/obo/UBERON_0003517 UBERON:0003515 biolink:AnatomicalEntity forelimb blood vessel A blood vessel that is part of a forelimb [Automatically generated definition]. go-plus.json fore limb blood vessel|anteriormost limb blood vessel|wing blood vessel|blood vessel of forelimb|blood vessel of anteriormost limb|blood vessel of upper extremity|blood vessel of fore limb http://purl.obolibrary.org/obo/UBERON_0003515 UBERON:0003516 biolink:AnatomicalEntity hindlimb blood vessel A blood vessel that is part of a hindlimb [Automatically generated definition]. go-plus.json hind limb blood vessel|blood vessel of hind limb|blood vessel of lower extremity|blood vessel of hindlimb http://purl.obolibrary.org/obo/UBERON_0003516 GO:0045325 biolink:BiologicalProcess peptidyl-tryptophan hydroxylation The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan. RESID:AA0322 go-plus.json http://purl.obolibrary.org/obo/GO_0045325 GO:0045326 biolink:BiologicalProcess protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine. RESID:AA0323 go-plus.json DNA-protein covalent cross-linking via the 3'-end to peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0045326 GO:0045323 biolink:CellularComponent interleukin-1 receptor complex A protein complex that binds interleukin-1; comprises an alpha and a beta subunit. go-plus.json IL-1 receptor complex http://purl.obolibrary.org/obo/GO_0045323 GO:0045324 biolink:BiologicalProcess late endosome to vacuole transport The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport. go-plus.json http://purl.obolibrary.org/obo/GO_0045324 GO:0045321 biolink:BiologicalProcess leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. Wikipedia:Immunologic_activation go-plus.json immune cell activation|leucocyte activation http://purl.obolibrary.org/obo/GO_0045321 GO:0045322 biolink:MolecularActivity unmethylated CpG binding Binding to uan nmethylated CpG motif. Unmethylated CpG dinucleotides are often associated with gene promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0045322 GO:0045320 biolink:CellularComponent chloroplast proton-transporting ATP synthase complex A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation. go-plus.json hydrogen-translocating F-type ATPase complex|chloroplast hydrogen-translocating F-type ATPase complex|chloroplast proton-transporting F-type ATPase complex http://purl.obolibrary.org/obo/GO_0045320 GO:0060940 biolink:BiologicalProcess epithelial to mesenchymal transition involved in cardiac fibroblast development A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast. go-plus.json http://purl.obolibrary.org/obo/GO_0060940 GO:0045329 biolink:BiologicalProcess carnitine biosynthetic process The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. go-plus.json carnitine anabolism|carnitine biosynthesis|carnitine synthesis|vitamin Bt biosynthetic process|carnitine formation|vitamin Bt biosynthesis http://purl.obolibrary.org/obo/GO_0045329 GO:0060941 biolink:BiologicalProcess epicardium-derived cardiac fibroblast cell fate commitment The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060941 GO:0060942 biolink:BiologicalProcess neural crest-derived cardiac fibroblast cell differentiation The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060942 GO:0045327 biolink:BiologicalProcess protein-DNA covalent cross-linking via peptidyl-tyrosine The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue. go-plus.json DNA-protein covalent cross-linking via peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0045327 GO:0060943 biolink:BiologicalProcess neural crest-derived cardiac fibroblast cell development The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060943 GO:0045328 biolink:BiologicalProcess cytochrome P450 4A1-heme linkage The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester. RESID:AA0324 go-plus.json cytochrome P450 4A1-haem linkage http://purl.obolibrary.org/obo/GO_0045328 UBERON:0003524 biolink:AnatomicalEntity tail blood vessel A blood vessel that is part of a tail [Automatically generated definition]. go-plus.json blood vessel of tail|post-vent region blood vessel|blood vessel of post-vent region http://purl.obolibrary.org/obo/UBERON_0003524 GO:0060944 biolink:BiologicalProcess neural crest-derived cardiac fibroblast cell fate commitment The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json http://purl.obolibrary.org/obo/GO_0060944 GO:0060945 biolink:BiologicalProcess cardiac neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. go-plus.json heart neuron differentiation http://purl.obolibrary.org/obo/GO_0060945 UBERON:0003522 biolink:AnatomicalEntity manual digit blood vessel A blood vessel that is part of a finger [Automatically generated definition]. go-plus.json blood vessel of terminal segment of free upper limb digit|finger blood vessel|digit of terminal segment of free upper limb blood vessel|hand digit blood vessel|terminal segment of free upper limb digit blood vessel|hand digit blood vessel|blood vessel of digit of terminal segment of free upper limb http://purl.obolibrary.org/obo/UBERON_0003522 GO:0060946 biolink:BiologicalProcess cardiac blood vessel endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0060946 UBERON:0003523 biolink:AnatomicalEntity manus blood vessel A blood vessel that is part of a manus [Automatically generated definition]. go-plus.json blood vessel of hand|blood vessel of manus|hand blood vessel http://purl.obolibrary.org/obo/UBERON_0003523 GO:0060947 biolink:BiologicalProcess cardiac vascular smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. go-plus.json heart vascular smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0060947 UBERON:0003520 biolink:AnatomicalEntity pelvis blood vessel A blood vessel that is part of a pelvis [Automatically generated definition]. go-plus.json blood vessel of pelvis http://purl.obolibrary.org/obo/UBERON_0003520 GO:0060948 biolink:BiologicalProcess cardiac vascular smooth muscle cell development The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state. go-plus.json heart vascular smooth muscle cell development http://purl.obolibrary.org/obo/GO_0060948 UBERON:0003521 biolink:AnatomicalEntity pes blood vessel A blood vessel that is part of a foot [Automatically generated definition]. go-plus.json blood vessel of foot|foot blood vessel http://purl.obolibrary.org/obo/UBERON_0003521 GO:0060949 biolink:BiologicalProcess cardiac vascular smooth muscle cell fate commitment The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell. go-plus.json heart vascular smooth muscle cell fate commitment http://purl.obolibrary.org/obo/GO_0060949 CHEBI:46574 biolink:ChemicalSubstance wybutosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_46574 chebi_ph7_3 UBERON:0003508 biolink:AnatomicalEntity pedal digit blood vessel A blood vessel that is part of a toe [Automatically generated definition]. go-plus.json digitus pedis blood vessel|digit of foot blood vessel|blood vessel of terminal segment of free lower limb digit|hind limb digit blood vessel|toe blood vessel|foot digit blood vessel|digit of terminal segment of free lower limb blood vessel|blood vessel of toe|terminal segment of free lower limb digit blood vessel|foot digit blood vessel|blood vessel of foot digit|blood vessel of digit of foot|blood vessel of digitus pedis|blood vessel of digit of terminal segment of free lower limb http://purl.obolibrary.org/obo/UBERON_0003508 UBERON:0003509 biolink:AnatomicalEntity arterial blood vessel A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003509 UBERON:0003506 biolink:AnatomicalEntity chest blood vessel A blood vessel that is part of a chest [Automatically generated definition]. go-plus.json blood vessel of anterolateral part of thorax|anterolateral part of thorax blood vessel|anterior thoracic region blood vessel|blood vessel of anterior thoracic region|blood vessel of chest|front of thorax blood vessel|blood vessel of front of thorax http://purl.obolibrary.org/obo/UBERON_0003506 UBERON:0003507 biolink:AnatomicalEntity arm blood vessel A blood vessel that is part of an arm [Automatically generated definition]. go-plus.json blood vessel of arm http://purl.obolibrary.org/obo/UBERON_0003507 UBERON:0003504 biolink:AnatomicalEntity respiratory system blood vessel A blood vessel that is part of a respiratory system [Automatically generated definition]. go-plus.json blood vessel of apparatus respiratorius|blood vessel of respiratory system|apparatus respiratorius blood vessel http://purl.obolibrary.org/obo/UBERON_0003504 UBERON:0003505 biolink:AnatomicalEntity trachea blood vessel A blood vessel that is part of a trachea. go-plus.json blood vessel of trachea http://purl.obolibrary.org/obo/UBERON_0003505 GO:0045336 biolink:CellularComponent clathrin-coated phagocytic vesicle A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. go-plus.json clathrin-coated phagosome http://purl.obolibrary.org/obo/GO_0045336 GO:0045337 biolink:BiologicalProcess farnesyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of farnesyl diphosphate. MetaCyc:PWY-5123 go-plus.json farnesyl diphosphate anabolism|farnesyl diphosphate synthesis|farnesyl diphosphate formation|farnesyl diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0045337 GO:0045334 biolink:CellularComponent clathrin-coated endocytic vesicle A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. NIF_Subcellular:sao1243595998 go-plus.json http://purl.obolibrary.org/obo/GO_0045334 GO:0045335 biolink:CellularComponent phagocytic vesicle A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. Wikipedia:Phagosome go-plus.json phagosome http://purl.obolibrary.org/obo/GO_0045335 GO:0045332 biolink:BiologicalProcess phospholipid translocation The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. go-plus.json phospholipid scrambling|flippase http://purl.obolibrary.org/obo/GO_0045332 CHEBI:46570 biolink:ChemicalSubstance cis-zeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_46570 chebi_ph7_3 GO:0045333 biolink:BiologicalProcess cellular respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). Wikipedia:Cellular_respiration go-plus.json respiration|oxidative metabolism|oxidative metabolic process http://purl.obolibrary.org/obo/GO_0045333 goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus GO:0045330 biolink:MolecularActivity aspartyl esterase activity Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue. go-plus.json http://purl.obolibrary.org/obo/GO_0045330 GO:0045331 biolink:MolecularActivity obsolete coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity OBSOLETE. Catalysis of the reaction: coenzyme-M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + H2 = coenzyme-M + N-(7-mercaptoheptanoyl)threonine O3-phosphate. go-plus.json heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulphide hydrogenase activity http://purl.obolibrary.org/obo/GO_0045331 GO:0060970 biolink:BiologicalProcess embryonic heart tube dorsal/ventral pattern formation The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis. go-plus.json http://purl.obolibrary.org/obo/GO_0060970 GO:0060971 biolink:BiologicalProcess embryonic heart tube left/right pattern formation The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place. go-plus.json http://purl.obolibrary.org/obo/GO_0060971 GO:0060972 biolink:BiologicalProcess left/right pattern formation The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060972 GO:0060973 biolink:BiologicalProcess cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. go-plus.json http://purl.obolibrary.org/obo/GO_0060973 GO:0060974 biolink:BiologicalProcess cell migration involved in heart formation The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060974 GO:0060975 biolink:BiologicalProcess cardioblast migration to the midline involved in heart field formation The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json cardiac progenitor cell midline migration|cardioblast midline convergence http://purl.obolibrary.org/obo/GO_0060975 GO:0045338 biolink:BiologicalProcess farnesyl diphosphate metabolic process The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation. go-plus.json farnesyl diphosphate metabolism http://purl.obolibrary.org/obo/GO_0045338 GO:0060976 biolink:BiologicalProcess coronary vasculature development The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. go-plus.json heart vasculature development|cardiac blood vessel development|cardiac vasculature development|coronary blood vessel development|heart blood vessel development http://purl.obolibrary.org/obo/GO_0060976 GO:0045339 biolink:BiologicalProcess farnesyl diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate. go-plus.json farnesyl diphosphate breakdown|farnesyl diphosphate catabolism|farnesyl diphosphate degradation http://purl.obolibrary.org/obo/GO_0045339 UBERON:0003513 biolink:AnatomicalEntity trunk blood vessel A blood vessel that is part of a trunk [Automatically generated definition]. go-plus.json blood vessel of trunk|blood vessel of torso|torso blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 GO:0060977 biolink:BiologicalProcess coronary vasculature morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. go-plus.json cardiac blood vessel morphogenesis|cardiac vasculature morphogenesis|coronary blood vessel morphogenesis|heart blood vessel morphogenesis|heart vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0060977 GO:0060978 biolink:BiologicalProcess angiogenesis involved in coronary vascular morphogenesis Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. go-plus.json angiogenesis involved in cardiac vascular morphogenesis|coronary vasculature angiogenesis|angiogenesis involved in heart vascular morphogenesis|coronary blood vessel angiogenesis http://purl.obolibrary.org/obo/GO_0060978 UBERON:0003514 biolink:AnatomicalEntity limb blood vessel A blood vessel that is part of a limb [Automatically generated definition]. go-plus.json blood vessel of limb http://purl.obolibrary.org/obo/UBERON_0003514 UBERON:0003511 biolink:AnatomicalEntity iris blood vessel A blood vessel that is part of a iris [Automatically generated definition]. go-plus.json blood vessel of iris http://purl.obolibrary.org/obo/UBERON_0003511 GO:0060979 biolink:BiologicalProcess vasculogenesis involved in coronary vascular morphogenesis The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. go-plus.json vasculogenesis involved in coronary blood vessel morphogenesis|coronary vasculogenesis http://purl.obolibrary.org/obo/GO_0060979 UBERON:0003512 biolink:AnatomicalEntity lung blood vessel A blood vessel that is part of a lung [Automatically generated definition]. go-plus.json pulmonary vascular element|blood vessel of lung http://purl.obolibrary.org/obo/UBERON_0003512 UBERON:0003510 biolink:AnatomicalEntity eyelid blood vessel A blood vessel that is part of a eyelid [Automatically generated definition]. go-plus.json blood vessel of blepharon|blood vessel of eyelid|blepharon blood vessel http://purl.obolibrary.org/obo/UBERON_0003510 GO:0045340 biolink:MolecularActivity mercury ion binding Binding to a mercury ion (Hg). go-plus.json mercury binding|Hg ion binding http://purl.obolibrary.org/obo/GO_0045340 GO:0045347 biolink:BiologicalProcess negative regulation of MHC class II biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. go-plus.json negative regulation of major histocompatibility complex class II biosynthetic process|negative regulation of major histocompatibility complex class II biosynthesis|down regulation of MHC class II biosynthetic process|downregulation of MHC class II biosynthetic process|negative regulation of MHC class II anabolism|negative regulation of MHC class II synthesis|negative regulation of MHC class II formation|negative regulation of MHC class II biosynthesis|down-regulation of MHC class II biosynthetic process|inhibition of MHC class II biosynthetic process http://purl.obolibrary.org/obo/GO_0045347 GO:0045348 biolink:BiologicalProcess positive regulation of MHC class II biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. go-plus.json upregulation of MHC class II biosynthetic process|positive regulation of major histocompatibility complex class II biosynthesis|positive regulation of major histocompatibility complex class II biosynthetic process|up regulation of MHC class II biosynthetic process|activation of MHC class II biosynthetic process|positive regulation of MHC class II anabolism|positive regulation of MHC class II biosynthesis|stimulation of MHC class II biosynthetic process|positive regulation of MHC class II synthesis|positive regulation of MHC class II formation|up-regulation of MHC class II biosynthetic process http://purl.obolibrary.org/obo/GO_0045348 GO:0045345 biolink:BiologicalProcess positive regulation of MHC class I biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. go-plus.json positive regulation of MHC class I synthesis|positive regulation of MHC class I formation|positive regulation of MHC class I biosynthesis|up regulation of MHC class I biosynthetic process|positive regulation of major histocompatibility complex class I biosynthetic process|positive regulation of major histocompatibility complex class I biosynthesis|upregulation of MHC class I biosynthetic process|stimulation of MHC class I biosynthetic process|activation of MHC class I biosynthetic process|up-regulation of MHC class I biosynthetic process|positive regulation of MHC class I anabolism http://purl.obolibrary.org/obo/GO_0045345 GO:0045346 biolink:BiologicalProcess regulation of MHC class II biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. go-plus.json regulation of MHC class II biosynthesis|regulation of major histocompatibility complex class II biosynthetic process|regulation of major histocompatibility complex class II biosynthesis|regulation of MHC class II anabolism|regulation of MHC class II synthesis|regulation of MHC class II formation http://purl.obolibrary.org/obo/GO_0045346 GO:0045343 biolink:BiologicalProcess regulation of MHC class I biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. go-plus.json regulation of major histocompatibility complex class I biosynthetic process|regulation of major histocompatibility complex class I biosynthesis|regulation of MHC class I biosynthesis|regulation of MHC class I anabolism|regulation of MHC class I synthesis|regulation of MHC class I formation http://purl.obolibrary.org/obo/GO_0045343 GO:0045344 biolink:BiologicalProcess negative regulation of MHC class I biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. go-plus.json down-regulation of MHC class I biosynthetic process|negative regulation of MHC class I biosynthesis|negative regulation of MHC class I synthesis|negative regulation of MHC class I formation|downregulation of MHC class I biosynthetic process|down regulation of MHC class I biosynthetic process|negative regulation of major histocompatibility complex class I biosynthesis|negative regulation of major histocompatibility complex class I biosynthetic process|inhibition of MHC class I biosynthetic process|negative regulation of MHC class I anabolism http://purl.obolibrary.org/obo/GO_0045344 GO:0045341 biolink:BiologicalProcess MHC class I biosynthetic process The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I. go-plus.json MHC class I anabolism|MHC class I synthesis|MHC class I formation|major histocompatibility complex class I biosynthesis|major histocompatibility complex class I biosynthetic process|MHC class I biosynthesis http://purl.obolibrary.org/obo/GO_0045341 GO:0045342 biolink:BiologicalProcess MHC class II biosynthetic process The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II. go-plus.json major histocompatibility complex class II biosynthesis|major histocompatibility complex class II biosynthetic process|MHC class II anabolism|MHC class II synthesis|MHC class II formation|MHC class II biosynthesis http://purl.obolibrary.org/obo/GO_0045342 GO:0060960 biolink:BiologicalProcess cardiac neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart. go-plus.json heart neuron fate commitment http://purl.obolibrary.org/obo/GO_0060960 GO:0060961 biolink:MolecularActivity phospholipase D inhibitor activity Binds to and stops, prevents or reduces the activity of phospholipase D. go-plus.json http://purl.obolibrary.org/obo/GO_0060961 GO:0060962 biolink:BiologicalProcess regulation of ribosomal protein gene transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. go-plus.json regulation of ribosomal protein gene transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0060962 GO:0060963 biolink:BiologicalProcess positive regulation of ribosomal protein gene transcription by RNA polymerase II Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. go-plus.json positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0060963 GO:0045349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045349 GO:0060964 biolink:BiologicalProcess regulation of gene silencing by miRNA Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: RNA (often mRNA) cleavage or mRNA translational repression. go-plus.json regulation of gene silencing by microRNA http://purl.obolibrary.org/obo/GO_0060964 GO:0060965 biolink:BiologicalProcess negative regulation of gene silencing by miRNA Any process that decreases the rate, frequency, or extent of gene silencing by miRNA. go-plus.json negative regulation of gene silencing by microRNA http://purl.obolibrary.org/obo/GO_0060965 UBERON:0003502 biolink:AnatomicalEntity neck blood vessel A blood vessel that is part of a neck [Automatically generated definition]. go-plus.json neck (volume) blood vessel|blood vessel of neck|blood vessel of neck (volume) http://purl.obolibrary.org/obo/UBERON_0003502 GO:0060966 biolink:BiologicalProcess regulation of gene silencing by RNA Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. go-plus.json http://purl.obolibrary.org/obo/GO_0060966 UBERON:0003503 biolink:AnatomicalEntity leg blood vessel A blood vessel that is part of a leg [Automatically generated definition]. go-plus.json blood vessel of leg http://purl.obolibrary.org/obo/UBERON_0003503 GO:0060967 biolink:BiologicalProcess negative regulation of gene silencing by RNA Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. go-plus.json http://purl.obolibrary.org/obo/GO_0060967 UBERON:0003500 biolink:AnatomicalEntity corneal blood vessel A blood vessel that is part of a cornea [Automatically generated definition]. go-plus.json blood vessel of cornea|cornea blood vessel http://purl.obolibrary.org/obo/UBERON_0003500 GO:0060968 biolink:BiologicalProcess regulation of gene silencing Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. go-plus.json http://purl.obolibrary.org/obo/GO_0060968 UBERON:0003501 biolink:AnatomicalEntity retina blood vessel A blood vessel that is part of a retina [Automatically generated definition]. go-plus.json retinal blood vessel|blood vessel of inner layer of eyeball|blood vessel of retina|tunica interna of eyeball blood vessel|inner layer of eyeball blood vessel|blood vessel of tunica interna of eyeball http://purl.obolibrary.org/obo/UBERON_0003501 GO:0060969 biolink:BiologicalProcess negative regulation of gene silencing Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. go-plus.json http://purl.obolibrary.org/obo/GO_0060969 CHEBI:71510 biolink:ChemicalSubstance anthocyanidin 3,5-di-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71510 CHEBI:71511 biolink:ChemicalSubstance cyanin betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71511 chebi_ph7_3 CHEBI:71512 biolink:ChemicalSubstance 1-O-vanilloyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_71512 chebi_ph7_3 CHEBI:71513 biolink:ChemicalSubstance cyanidin 3,7-di-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71513 chebi_ph7_3 CHEBI:71515 biolink:ChemicalSubstance cyanidin 3-O-beta-D-galactoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71515 CHEBI:71516 biolink:ChemicalSubstance cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside](1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71516 chebi_ph7_3 CHEBI:71517 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71517 chebi_ph7_3 CHEBI:71519 biolink:ChemicalSubstance anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71519 chebi_ph7_3 CHEBI:71522 biolink:ChemicalSubstance anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71522 CHEBI:71531 biolink:ChemicalSubstance gypsogenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71531 CHEBI:71533 biolink:ChemicalSubstance norsolorinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71533 chebi_ph7_3 CHEBI:71534 biolink:ChemicalSubstance (S)-averantin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71534 CHEBI:71535 biolink:ChemicalSubstance (1'S,5'S)-5'-hydroxyaverantin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71535 CHEBI:71536 biolink:ChemicalSubstance (1'S,5'R)-5'-hydroxyaverantin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71536 chebi_ph7_3 CHEBI:71537 biolink:ChemicalSubstance (1'S,5'S)-averufin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71537 chebi_ph7_3 CHEBI:71539 biolink:ChemicalSubstance (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71539 CHEBI:71541 biolink:ChemicalSubstance (25S)-Delta(4)-dafachronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71541 chebi_ph7_3 CHEBI:71542 biolink:ChemicalSubstance (25S)-Delta(7)-dafachronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71542 chebi_ph7_3 CHEBI:71543 biolink:ChemicalSubstance rotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71543 CHEBI:71544 biolink:ChemicalSubstance (E)-isopentadec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71544 GO:0035999 biolink:BiologicalProcess tetrahydrofolate interconversion The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules. UniPathway:UPA00193|MetaCyc:PWY-2201 go-plus.json http://purl.obolibrary.org/obo/GO_0035999 CHEBI:141697 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141697 chebi_ph7_3 CHEBI:141698 biolink:ChemicalSubstance L,L-homocystine go-plus.json http://purl.obolibrary.org/obo/CHEBI_141698 GO:0035991 biolink:MolecularActivity nitric oxide sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO). go-plus.json NO sensor activity http://purl.obolibrary.org/obo/GO_0035991 GO:0035992 biolink:BiologicalProcess tendon formation The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0035992 GO:0035993 biolink:BiologicalProcess deltoid tuberosity development The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase. go-plus.json http://purl.obolibrary.org/obo/GO_0035993 GO:0035994 biolink:BiologicalProcess response to muscle stretch Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length. go-plus.json http://purl.obolibrary.org/obo/GO_0035994 GO:0035995 biolink:BiologicalProcess detection of muscle stretch The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0035995 GO:0035996 biolink:CellularComponent rhabdomere microvillus Thin cylindrical membrane-covered projection on the surface of a rhabdomere. go-plus.json http://purl.obolibrary.org/obo/GO_0035996 GO:0035997 biolink:CellularComponent rhabdomere microvillus membrane The portion of the plasma membrane surrounding a microvillus of a rhabdomere. go-plus.json http://purl.obolibrary.org/obo/GO_0035997 GO:0035998 biolink:BiologicalProcess 7,8-dihydroneopterin 3'-triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate. UniPathway:UPA00848 go-plus.json 7,8-dihydroneopterin 3'-triphosphate biosynthesis|7,8-dihydroneopterin 3'-triphosphate anabolism|7,8-dihydroneopterin 3'-triphosphate synthesis|7,8-dihydroneopterin 3'-triphosphate formation http://purl.obolibrary.org/obo/GO_0035998 GO:0035990 biolink:BiologicalProcess tendon cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance. go-plus.json tenocyte differentiation|muscle attachment cell differentiation http://purl.obolibrary.org/obo/GO_0035990 CHEBI:71540 biolink:ChemicalSubstance isoheptadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71540 CHEBI:71554 biolink:ChemicalSubstance PPARgamma agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_71554 CHEBI:71556 biolink:ChemicalSubstance (25S)-Delta(7)-dafachronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71556 GO:0035988 biolink:BiologicalProcess chondrocyte proliferation The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json chondrocyte cell proliferation|cartilage cell proliferation http://purl.obolibrary.org/obo/GO_0035988 GO:0035989 biolink:BiologicalProcess tendon development The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. go-plus.json sinew development http://purl.obolibrary.org/obo/GO_0035989 GO:0035980 biolink:BiologicalProcess obsolete invasive growth in response to nitrogen limitation OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen. go-plus.json invasive growth in response to nitrogen limitation http://purl.obolibrary.org/obo/GO_0035980 GO:0035981 biolink:BiologicalProcess tongue muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0035981 GO:0035982 biolink:BiologicalProcess obsolete age-dependent behavioral decline OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory. go-plus.json behavioral aging|age-related behavioral decline|age-dependent behavioural decline http://purl.obolibrary.org/obo/GO_0035982 GO:0035983 biolink:BiologicalProcess response to trichostatin A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0035983 GO:0035984 biolink:BiologicalProcess cellular response to trichostatin A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0035984 GO:0035985 biolink:CellularComponent senescence-associated heterochromatin focus A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes. go-plus.json senescence-associated heterochromatin foci|SAHF http://purl.obolibrary.org/obo/GO_0035985 GO:0035986 biolink:BiologicalProcess obsolete senescence-associated heterochromatin focus assembly OBSOLETE. The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes. go-plus.json senescence-associated heterochromatin focus formation|SAHF formation|senescence-associated heterochromatin foci formation http://purl.obolibrary.org/obo/GO_0035986 GO:0035987 biolink:BiologicalProcess endodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. go-plus.json endoderm cell differentiation http://purl.obolibrary.org/obo/GO_0035987 CHEBI:71550 biolink:ChemicalSubstance lathosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71550 chebi_ph7_3 CHEBI:71551 biolink:ChemicalSubstance EC 3.5.1.23 (ceramidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_71551 CHEBI:71563 biolink:ChemicalSubstance all-cis-8,11,14,17-icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71563 chebi_ph7_3 CHEBI:71566 biolink:ChemicalSubstance precorrin-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_71566 CHEBI:71567 biolink:ChemicalSubstance (25S)-cholestenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71567 chebi_ph7_3 GO:0035977 biolink:BiologicalProcess protein deglycosylation involved in glycoprotein catabolic process The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0035977 GO:0035978 biolink:BiologicalProcess histone H2A-S139 phosphorylation The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone. go-plus.json histone H2A.x phosphorylation at S139 http://purl.obolibrary.org/obo/GO_0035978 GO:0035979 biolink:MolecularActivity histone kinase activity (H2A-S139 specific) Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A. go-plus.json histone kinase activity (H2A.x-S139 specific) http://purl.obolibrary.org/obo/GO_0035979 GO:0035970 biolink:BiologicalProcess peptidyl-threonine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0035970 GO:0035971 biolink:BiologicalProcess peptidyl-histidine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine. go-plus.json http://purl.obolibrary.org/obo/GO_0035971 GO:0035972 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035972 GO:0035973 biolink:BiologicalProcess aggrephagy Selective degradation of protein aggregates by macroautophagy. go-plus.json http://purl.obolibrary.org/obo/GO_0035973 GO:0035974 biolink:CellularComponent meiotic spindle pole body The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0035974 GO:0035975 biolink:BiologicalProcess carbamoyl phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways. go-plus.json carbamoyl phosphate degradation|carbamoyl phosphate catabolism|carbamoyl phosphate breakdown http://purl.obolibrary.org/obo/GO_0035975 GO:0035976 biolink:CellularComponent transcription factor AP-1 complex A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes. go-plus.json transcription factor AP1 complex|AP-1 complex|Activating protein 1 complex|AP1 complex http://purl.obolibrary.org/obo/GO_0035976 CHEBI:71560 biolink:ChemicalSubstance (25S)-Delta(4)-dafachronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71560 CHEBI:71574 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71574 CHEBI:71576 biolink:ChemicalSubstance 30-hydroxy-11-oxo-beta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71576 chebi_ph7_3 CHEBI:71577 biolink:ChemicalSubstance glycyrrhetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_71577 chebi_ph7_3 CHEBI:71578 biolink:ChemicalSubstance cyclic di-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_71578 CHEBI:71579 biolink:ChemicalSubstance methyl red(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71579 chebi_ph7_3 GO:0035966 biolink:BiologicalProcess response to topologically incorrect protein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure. go-plus.json response to misfolded or unfolded protein http://purl.obolibrary.org/obo/GO_0035966 GO:0035967 biolink:BiologicalProcess cellular response to topologically incorrect protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure. go-plus.json cellular response to misfolded or unfolded protein http://purl.obolibrary.org/obo/GO_0035967 GO:0035968 biolink:BiologicalProcess obsolete regulation of sterol import by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter. go-plus.json regulation of sterol influx by regulation of transcription from Pol II promoter|regulation of sterol uptake by regulation of transcription from RNA polymerase II promoter|regulation of sterol uptake by regulation of transcription from Pol II promoter|regulation of sterol influx by regulation of transcription from RNA polymerase II promoter|regulation of sterol import by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035968 GO:0035969 biolink:BiologicalProcess obsolete positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by positive regulation of transcription from Pol II promoter|positive regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035969 GO:0035960 biolink:BiologicalProcess obsolete regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of ergosterol formation by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol synthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol anabolism by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol biosynthesis by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthetic process by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol anabolism by regulation of transcription from Pol II promoter|regulation of ergosterol synthesis by regulation of transcription from Pol II promoter|regulation of ergosterol formation by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035960 GO:0035961 biolink:BiologicalProcess obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of ergosterol formation by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by stimulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthetic process by activation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035961 GO:0035962 biolink:BiologicalProcess response to interleukin-13 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus. go-plus.json response to IL-13 http://purl.obolibrary.org/obo/GO_0035962 CHEBI:141668 biolink:ChemicalSubstance L-tyrosinal(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141668 chebi_ph7_3 GO:0035963 biolink:BiologicalProcess cellular response to interleukin-13 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus. go-plus.json cellular response to IL-13 http://purl.obolibrary.org/obo/GO_0035963 GO:0035964 biolink:BiologicalProcess COPI-coated vesicle budding The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle. go-plus.json COPI vesicle budding http://purl.obolibrary.org/obo/GO_0035964 GO:0035965 biolink:BiologicalProcess cardiolipin acyl-chain remodeling Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids. go-plus.json diphosphatidylglycerol remodeling|cardiolipin maturation|cardiolipin acyl-chain remodelling http://purl.obolibrary.org/obo/GO_0035965 CHEBI:71570 biolink:ChemicalSubstance (25R)-Delta(4)-dafachronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71570 chebi_ph7_3 CHEBI:71572 biolink:ChemicalSubstance (2R)-3-(3,4-dihydroxyphenyl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71572 CHEBI:71573 biolink:ChemicalSubstance UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71573 chebi_ph7_3 CHEBI:71586 biolink:ChemicalSubstance (3E,5Z)-tetradecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71586 chebi_ph7_3 CHEBI:71587 biolink:ChemicalSubstance cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside] go-plus.json http://purl.obolibrary.org/obo/CHEBI_71587 CHEBI:71589 biolink:ChemicalSubstance all-cis-icosa-8,11,14-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71589 chebi_ph7_3 GO:0035955 biolink:BiologicalProcess obsolete negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of dipeptide transport by down regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by downregulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of dipeptide transport by inhibition of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035955 GO:0035956 biolink:BiologicalProcess obsolete regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|regulation of starch degradation by regulation of transcription from Pol II promoter|regulation of starch catabolic process by regulation of transcription from Pol II promoter|regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter|regulation of starch catabolism by regulation of transcription from Pol II promoter|regulation of starch breakdown by regulation of transcription from Pol II promoter|regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035956 GO:0035957 biolink:BiologicalProcess obsolete positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of starch degradation by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from Pol II promoter|positive regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolic process by regulation of transcription from Pol II promoter|positive regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolism by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035957 GO:0035958 biolink:BiologicalProcess obsolete regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of glyoxylate bypass by regulation of transcription from RNA polymerase II promoter|regulation of glyoxylate cycle by regulation of transcription from Pol II promoter|regulation of glyoxylate bypass by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035958 GO:0035959 biolink:BiologicalProcess obsolete positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of glyoxylate bypass by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate cycle by stimulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate bypass by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by up regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by activation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035959 GO:0035950 biolink:BiologicalProcess obsolete regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter. go-plus.json regulation of oligopeptide transport by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035950 GO:0035951 biolink:BiologicalProcess obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of oligopeptide transport by positive regulation of transcription from Pol II promoter|positive regulation of oligopeptide transport by upregulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by up regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035951 GO:0035952 biolink:BiologicalProcess obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of oligopeptide transport by inhibition of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of oligopeptide transport by downregulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0035952 GO:0035953 biolink:BiologicalProcess obsolete regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter. go-plus.json regulation of dipeptide transport by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035953 GO:0035954 biolink:BiologicalProcess obsolete positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of dipeptide transport by upregulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by positive regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0035954 CHEBI:71580 biolink:ChemicalSubstance c-GMP-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_71580 CHEBI:71583 biolink:ChemicalSubstance anthocyanidin glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71583 CHEBI:71584 biolink:ChemicalSubstance cyanidin 3,7-di-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71584 GO:0070273 biolink:MolecularActivity phosphatidylinositol-4-phosphate binding Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position. go-plus.json http://purl.obolibrary.org/obo/GO_0070273 GO:0070274 biolink:CellularComponent RES complex A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p. go-plus.json pre-mRNA retention and splicing complex http://purl.obolibrary.org/obo/GO_0070274 GO:0070271 biolink:BiologicalProcess obsolete protein complex biogenesis OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex. go-plus.json protein complex biogenesis and assembly http://purl.obolibrary.org/obo/GO_0070271 GO:0070272 biolink:BiologicalProcess obsolete proton-transporting ATP synthase complex biogenesis OBSOLETE. The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. go-plus.json F-type ATPase complex biogenesis http://purl.obolibrary.org/obo/GO_0070272 CHEBI:22501 biolink:ChemicalSubstance aminodiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22501 GO:0070270 biolink:BiologicalProcess obsolete mitotic catastrophe OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation. go-plus.json cell death preceded by multinucleation|cell death occurring during metaphase|mitotic catastrophe http://purl.obolibrary.org/obo/GO_0070270 CHEBI:22502 biolink:ChemicalSubstance 2-aminoethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22502 CHEBI:22500 biolink:ChemicalSubstance aminobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_22500 CHEBI:22506 biolink:ChemicalSubstance aminoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_22506 GO:0070279 biolink:MolecularActivity vitamin B6 binding Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0070279 GO:0070277 biolink:BiologicalProcess iodide oxidation The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons. go-plus.json http://purl.obolibrary.org/obo/GO_0070277 GO:0070278 biolink:BiologicalProcess extracellular matrix constituent secretion The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. go-plus.json ECM constituent secretion|ECM secretion http://purl.obolibrary.org/obo/GO_0070278 CHEBI:22507 biolink:ChemicalSubstance aminoglycoside antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_22507 GO:0070275 biolink:BiologicalProcess aerobic ammonia oxidation to nitrite via pyruvic oxime The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite. MetaCyc:PWY-2242 go-plus.json http://purl.obolibrary.org/obo/GO_0070275 GO:0070276 biolink:BiologicalProcess halogen metabolic process The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds. go-plus.json halogen metabolism http://purl.obolibrary.org/obo/GO_0070276 GO:0070262 biolink:BiologicalProcess peptidyl-serine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0070262 GO:0070263 biolink:CellularComponent external side of fungal-type cell wall The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents. go-plus.json http://purl.obolibrary.org/obo/GO_0070263 GO:0070260 biolink:MolecularActivity 5'-tyrosyl-DNA phosphodiesterase activity Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070260 GO:0070261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070261 CHEBI:22512 biolink:ChemicalSubstance aminoimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_22512 GO:0070268 biolink:BiologicalProcess cornification A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). go-plus.json http://purl.obolibrary.org/obo/GO_0070268 GO:0070269 biolink:BiologicalProcess pyroptosis A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. go-plus.json http://purl.obolibrary.org/obo/GO_0070269 GO:0070266 biolink:BiologicalProcess necroptotic process A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former. go-plus.json programmed necrotic cell death|induction of necroptosis|programmed necrosis|TNF-induced necroptosis|induction of necroptosis of activated-T cells|activation of necroptosis in response to extracellular signals|extracellular signal-induced necroptosis|necroptosis|induction of necroptosis by extracellular signals|establishment of necroptosis of activated-T cells|activation of necroptosis of activated-T cells|RIPK1-mediated regulated necrosis|activation of necroptosis by extracellular signals|activation of necroptosis|establishment of necroptosis|parthanatos|PARP-dependent cell death http://purl.obolibrary.org/obo/GO_0070266 GO:0070267 biolink:BiologicalProcess oncosis A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0070267 GO:0070264 biolink:CellularComponent transcription factor TFIIIE complex A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0070264 GO:0070265 biolink:BiologicalProcess necrotic cell death A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. go-plus.json necrosis|cellular necrosis http://purl.obolibrary.org/obo/GO_0070265 GO:0070295 biolink:BiologicalProcess renal water absorption A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. go-plus.json nephron water absorption|renal water reabsorption http://purl.obolibrary.org/obo/GO_0070295 GO:0070296 biolink:BiologicalProcess sarcoplasmic reticulum calcium ion transport The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0070296 GO:0070293 biolink:BiologicalProcess renal absorption A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). go-plus.json renal reabsorption|nephron absorption http://purl.obolibrary.org/obo/GO_0070293 GO:0070294 biolink:BiologicalProcess renal sodium ion absorption A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. go-plus.json nephron sodium ion absorption|renal sodium ion reabsorption http://purl.obolibrary.org/obo/GO_0070294 GO:0070291 biolink:BiologicalProcess N-acylethanolamine metabolic process The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group. go-plus.json NAE metabolism|NAE metabolic process|N-acylethanolamine metabolism http://purl.obolibrary.org/obo/GO_0070291 GO:0070292 biolink:BiologicalProcess N-acylphosphatidylethanolamine metabolic process The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group. go-plus.json N-acylphosphatidylethanolamine metabolism|NAPE metabolic process|NAPE metabolism http://purl.obolibrary.org/obo/GO_0070292 GO:0070290 biolink:MolecularActivity N-acylphosphatidylethanolamine-specific phospholipase D activity Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE). Reactome:R-HSA-2466831|EC:3.1.4.4 go-plus.json N-acyl-phosphatidylethanolamine-specific phospholipase D activity|NAPE-specific phospholipase D activity http://purl.obolibrary.org/obo/GO_0070290 goslim_chembl NCBITaxon:33511 biolink:OrganismalEntity Deuterostomia go-plus.json deuterostomes http://purl.obolibrary.org/obo/NCBITaxon_33511 GO:0070299 biolink:BiologicalProcess positive regulation of phosphorelay signal transduction system Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system. go-plus.json positive regulation of two-component signal transduction system (phosphorelay)|positive regulation of histidyl-aspartyl phosphorelay|up regulation of two-component signal transduction|activation of two-component signal transduction|stimulation of two-component signal transduction|up-regulation of two-component signal transduction|upregulation of two-component signal transduction http://purl.obolibrary.org/obo/GO_0070299 GO:0070297 biolink:BiologicalProcess regulation of phosphorelay signal transduction system Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system. go-plus.json regulation of two-component signal transduction system|regulation of histidyl-aspartyl phosphorelay|regulation of two-component signal transduction system (phosphorelay) http://purl.obolibrary.org/obo/GO_0070297 GO:0070298 biolink:BiologicalProcess negative regulation of phosphorelay signal transduction system Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system. go-plus.json downregulation of two-component signal transduction|negative regulation of two-component signal transduction system (phosphorelay)|down-regulation of two-component signal transduction|inhibition of two-component signal transduction|down regulation of two-component signal transduction|negative regulation of histidyl-aspartyl phosphorelay http://purl.obolibrary.org/obo/GO_0070298 GO:0070284 biolink:MolecularActivity 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine. go-plus.json ThiC|HMP-P synthase activity http://purl.obolibrary.org/obo/GO_0070284 GO:0070285 biolink:BiologicalProcess pigment cell development The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0070285 GO:0070282 biolink:MolecularActivity pyridoxine binding Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0070282 GO:0070283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070283 GO:0070280 biolink:MolecularActivity pyridoxal binding Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0070280 GO:0070281 biolink:MolecularActivity pyridoxamine binding Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0070281 GO:0070288 biolink:CellularComponent ferritin complex A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain. go-plus.json http://purl.obolibrary.org/obo/GO_0070288 GO:0070289 biolink:CellularComponent extracellular ferritin complex A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains. go-plus.json serum ferritin complex http://purl.obolibrary.org/obo/GO_0070289 GO:0070286 biolink:BiologicalProcess axonemal dynein complex assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. go-plus.json dynein arm assembly http://purl.obolibrary.org/obo/GO_0070286 GO:0070287 biolink:MolecularActivity ferritin receptor activity Combining with ferritin, and delivering ferritin into the cell via endocytosis. go-plus.json ferritin complex receptor activity http://purl.obolibrary.org/obo/GO_0070287 NCBITaxon:33554 biolink:OrganismalEntity Carnivora go-plus.json carnivores|carnivores http://purl.obolibrary.org/obo/NCBITaxon_33554 CHEBI:71500 biolink:ChemicalSubstance cyclic di-AMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71500 chebi_ph7_3 CHEBI:71501 biolink:ChemicalSubstance c-GMP-AMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71501 chebi_ph7_3 CHEBI:71502 biolink:ChemicalSubstance beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71502 chebi_ph7_3 CHEBI:71505 biolink:ChemicalSubstance anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] go-plus.json http://purl.obolibrary.org/obo/CHEBI_71505 chebi_ph7_3 CHEBI:71506 biolink:ChemicalSubstance anthocyanidin 3-O-beta-D-sambubioside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71506 CHEBI:71507 biolink:ChemicalSubstance anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71507 CHEBI:71509 biolink:ChemicalSubstance anthocyanidin 3-O-sophoroside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71509 GO:0045230 biolink:BiologicalProcess capsule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi. go-plus.json capsule organisation|capsule organization and biogenesis http://purl.obolibrary.org/obo/GO_0045230 goslim_pir CHEBI:22586 biolink:ChemicalSubstance antioxidant go-plus.json http://purl.obolibrary.org/obo/CHEBI_22586 GO:1901969 biolink:BiologicalProcess positive regulation of polynucleotide 3'-phosphatase activity Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity. go-plus.json up-regulation of 2'(3')-polynucleotidase activity|activation of polynucleotide 3'-phosphohydrolase activity|upregulation of deoxyribonucleate 3'-phosphatase activity|up regulation of 5'-polynucleotidekinase 3'-phosphatase activity|activation of polynucleotide 3'-phosphatase activity|up-regulation of polynucleotide 3'-phosphatase activity|positive regulation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of DNA 3'-phosphatase activity|up-regulation of polynucleotide 3'-phosphohydrolase activity|activation of 2'(3')-polynucleotidase activity|positive regulation of DNA 3'-phosphatase activity|activation of 5'-polynucleotidekinase 3'-phosphatase activity|positive regulation of 2'(3')-polynucleotidase activity|activation of DNA 3'-phosphatase activity|up regulation of deoxyribonucleate 3'-phosphatase activity|positive regulation of deoxyribonucleate 3'-phosphatase activity|up regulation of 2'(3')-polynucleotidase activity|up-regulation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of polynucleotide 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphohydrolase activity|up-regulation of DNA 3'-phosphatase activity|activation of deoxyribonucleate 3'-phosphatase activity|upregulation of 2'(3')-polynucleotidase activity|upregulation of 5'-polynucleotidekinase 3'-phosphatase activity|up-regulation of deoxyribonucleate 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphatase activity|up regulation of polynucleotide 3'-phosphohydrolase activity|upregulation of DNA 3'-phosphatase activity|positive regulation of polynucleotide 3'-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_1901969 CHEBI:22583 biolink:ChemicalSubstance antifeedant go-plus.json http://purl.obolibrary.org/obo/CHEBI_22583 GO:1901967 biolink:BiologicalProcess negative regulation of cellular response to iron ion starvation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation. go-plus.json downregulation of cellular response to iron ion starvation|down regulation of cellular response to iron ion starvation|inhibition of cellular response to iron ion starvation|down-regulation of cellular response to iron ion starvation http://purl.obolibrary.org/obo/GO_1901967 GO:1901968 biolink:BiologicalProcess regulation of polynucleotide 3'-phosphatase activity Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity. go-plus.json regulation of DNA 3'-phosphatase activity|regulation of deoxyribonucleate 3'-phosphatase activity|regulation of 2'(3')-polynucleotidase activity|regulation of polynucleotide 3'-phosphohydrolase activity|regulation of 5'-polynucleotidekinase 3'-phosphatase activity http://purl.obolibrary.org/obo/GO_1901968 GO:1901965 biolink:BiologicalProcess endoplasmic reticulum to chloroplast transport The directed movement of substances from endoplasmic reticulum to chloroplast. go-plus.json ER to chloroplast transport http://purl.obolibrary.org/obo/GO_1901965 CHEBI:22587 biolink:ChemicalSubstance antiviral agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_22587 GO:1901966 biolink:BiologicalProcess regulation of cellular response to iron ion starvation Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1901966 GO:1901963 biolink:BiologicalProcess regulation of cell proliferation involved in outflow tract morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1901963 GO:0045237 biolink:MolecularActivity CXCR1 chemokine receptor binding Binding to a CXCR1 chemokine receptor. go-plus.json CXCR1 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0045237 GO:1901964 biolink:BiologicalProcess positive regulation of cell proliferation involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. go-plus.json up regulation of cell proliferation involved in outflow tract morphogenesis|upregulation of cell proliferation involved in outflow tract morphogenesis|up-regulation of cell proliferation involved in outflow tract morphogenesis|activation of cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1901964 GO:0045238 biolink:MolecularActivity CXCR2 chemokine receptor binding Binding to a CXCR2 chemokine receptor. go-plus.json CXCR2 chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0045238 GO:1901961 biolink:BiologicalProcess isobutanol biosynthetic process The chemical reactions and pathways resulting in the formation of isobutanol. go-plus.json isobutanol synthesis|isobutanol formation|isobutanol biosynthesis|isobutanol anabolism http://purl.obolibrary.org/obo/GO_1901961 GO:0045235 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045235 GO:0045236 biolink:MolecularActivity CXCR chemokine receptor binding Binding to a chemokine receptor in the CXCR family. go-plus.json CXC chemokine receptor ligand|C-X-C chemokine receptor ligand|alpha chemokine receptor binding|alpha chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0045236 GO:1901962 biolink:BiologicalProcess S-adenosyl-L-methionine transmembrane transport The directed movement of S-adenosyl-L-methionine across a membrane. go-plus.json S-adenosylmethionine transmembrane transport|SAM transmembrane transport http://purl.obolibrary.org/obo/GO_1901962 GO:0045233 biolink:MolecularActivity obsolete natural killer cell receptor activity OBSOLETE. A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family. go-plus.json Ly49i|NK cell receptor activity|natural killer cell receptor activity http://purl.obolibrary.org/obo/GO_0045233 GO:1901960 biolink:BiologicalProcess isobutanol metabolic process The chemical reactions and pathways involving isobutanol. go-plus.json isobutanol metabolism http://purl.obolibrary.org/obo/GO_1901960 GO:0045234 biolink:BiologicalProcess protein palmitoleylation The covalent attachment of a palmitoleyl group to a protein. go-plus.json protein amino acid palmitoleylation http://purl.obolibrary.org/obo/GO_0045234 GO:0045231 biolink:BiologicalProcess slime layer organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. go-plus.json slime layer organization and biogenesis|slime layer organisation http://purl.obolibrary.org/obo/GO_0045231 goslim_pir GO:0045232 biolink:BiologicalProcess S-layer organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria. go-plus.json S-layer organization and biogenesis|S-layer organisation http://purl.obolibrary.org/obo/GO_0045232 CHEBI:22580 biolink:ChemicalSubstance anthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_22580 UBERON:0003571 biolink:AnatomicalEntity trachea connective tissue A portion of connective tissue that is part of a trachea. go-plus.json connective tissue of windpipe|connective tissue of trachea http://purl.obolibrary.org/obo/UBERON_0003571 GO:0060870 biolink:BiologicalProcess cell wall disassembly involved in floral organ abscission A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission. go-plus.json http://purl.obolibrary.org/obo/GO_0060870 UBERON:0003572 biolink:AnatomicalEntity chest connective tissue A portion of connective tissue that is part of a chest [Automatically generated definition]. go-plus.json connective tissue of anterior thoracic region|anterolateral part of thorax portion of connective tissue|textus connectivus of chest|front of thorax connective tissue|textus connectivus of front of thorax|textus connectivus of anterolateral part of thorax|anterolateral part of thorax textus connectivus|portion of connective tissue of chest|portion of connective tissue of front of thorax|anterior thoracic region connective tissue|connective tissue of anterolateral part of thorax|anterior thoracic region portion of connective tissue|portion of connective tissue of anterior thoracic region|front of thorax portion of connective tissue|anterior thoracic region textus connectivus|chest portion of connective tissue|anterolateral part of thorax connective tissue|textus connectivus of anterior thoracic region|connective tissue of chest|front of thorax textus connectivus|connective tissue of front of thorax|chest textus connectivus|portion of connective tissue of anterolateral part of thorax http://purl.obolibrary.org/obo/UBERON_0003572 GO:0060871 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060871 GO:0060872 biolink:BiologicalProcess semicircular canal development The progression of the semicircular canal from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060872 OBO:GOCHE_76741 biolink:OntologyClass substance with EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76741 3_STAR UBERON:0003570 biolink:AnatomicalEntity respiratory system connective tissue A portion of connective tissue that is part of a respiratory system [Automatically generated definition]. go-plus.json portion of connective tissue of respiratory system|textus connectivus of apparatus respiratorius|apparatus respiratorius connective tissue|textus connectivus of respiratory system|apparatus respiratorius portion of connective tissue|portion of connective tissue of apparatus respiratorius|apparatus respiratorius textus connectivus|connective tissue of respiratory system|respiratory system portion of connective tissue|respiratory system textus connectivus|connective tissue of apparatus respiratorius http://purl.obolibrary.org/obo/UBERON_0003570 GO:0060873 biolink:BiologicalProcess anterior semicircular canal development The progession of the anterior semicircular canal from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060873 GO:0060874 biolink:BiologicalProcess posterior semicircular canal development The progession of the posterior semicircular canal from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060874 GO:0060875 biolink:BiologicalProcess lateral semicircular canal development The progession of the lateral semicircular canal from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060875 GO:0060876 biolink:BiologicalProcess semicircular canal formation The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. go-plus.json http://purl.obolibrary.org/obo/GO_0060876 GO:0045239 biolink:CellularComponent tricarboxylic acid cycle enzyme complex Any of the heteromeric enzymes that act in the TCA cycle. go-plus.json TCA cycle enzyme complex http://purl.obolibrary.org/obo/GO_0045239 goslim_pir GO:0060877 biolink:BiologicalProcess regionalization involved in semicircular canal formation The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals. go-plus.json http://purl.obolibrary.org/obo/GO_0060877 GO:0060878 biolink:BiologicalProcess pouch outgrowth involved in semicircular canal formation The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal. go-plus.json http://purl.obolibrary.org/obo/GO_0060878 UBERON:0003579 biolink:AnatomicalEntity shoulder connective tissue A portion of connective tissue that is part of a shoulder [Automatically generated definition]. go-plus.json portion of connective tissue of shoulder|textus connectivus of shoulder|shoulder portion of connective tissue|shoulder textus connectivus|connective tissue of shoulder http://purl.obolibrary.org/obo/UBERON_0003579 GO:0060879 biolink:BiologicalProcess semicircular canal fusion Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation. go-plus.json http://purl.obolibrary.org/obo/GO_0060879 UBERON:0003577 biolink:AnatomicalEntity knee connective tissue A portion of connective tissue that is part of a knee [Automatically generated definition]. go-plus.json knee portion of connective tissue|connective tissue of knee http://purl.obolibrary.org/obo/UBERON_0003577 UBERON:0003578 biolink:AnatomicalEntity pedal digit connective tissue A portion of connective tissue that is part of a toe [Automatically generated definition]. go-plus.json digitus pedis textus connectivus|connective tissue of foot digit|foot digit connective tissue|foot digit connective tissue|connective tissue of toe|connective tissue of digitus pedis|connective tissue of digit of foot|hind limb digit connective tissue http://purl.obolibrary.org/obo/UBERON_0003578 UBERON:0003575 biolink:AnatomicalEntity wrist connective tissue A portion of connective tissue that is part of a wrist [Automatically generated definition]. go-plus.json connective tissue of wrist|connective tissue of carpal region|carpal region connective tissue http://purl.obolibrary.org/obo/UBERON_0003575 UBERON:0003576 biolink:AnatomicalEntity hip connective tissue A portion of connective tissue that is part of a hip [Automatically generated definition]. go-plus.json connective tissue of hip|connective tissue of regio coxae|connective tissue of hip region http://purl.obolibrary.org/obo/UBERON_0003576 UBERON:0003573 biolink:AnatomicalEntity arm connective tissue A portion of connective tissue that is part of an arm [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003573 UBERON:0003574 biolink:AnatomicalEntity elbow connective tissue A portion of connective tissue that is part of a elbow [Automatically generated definition]. go-plus.json textus connectivus of cubital region|connective tissue of cubital region|connective tissue of elbow http://purl.obolibrary.org/obo/UBERON_0003574 GO:0045240 biolink:CellularComponent dihydrolipoyl dehydrogenase complex A protein complex that possesses alpha-ketoglutarate dehydrogenase activity. go-plus.json alpha-ketoglutarate dehydrogenase complex|2-oxoglutarate dehydrogenase complex http://purl.obolibrary.org/obo/GO_0045240 GO:0045241 biolink:CellularComponent cytosolic alpha-ketoglutarate dehydrogenase complex Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity. go-plus.json 2-oxoglutarate dehydrogenase complex http://purl.obolibrary.org/obo/GO_0045241 CHEBI:22595 biolink:ChemicalSubstance arabinonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22595 GO:1901978 biolink:BiologicalProcess positive regulation of cell cycle checkpoint Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint. go-plus.json positive regulation of G1/S checkpoint|up regulation of cell cycle checkpoint|activation of cell cycle checkpoint|positive regulation of G1/S transition checkpoint|up-regulation of cell cycle checkpoint|upregulation of cell cycle checkpoint http://purl.obolibrary.org/obo/GO_1901978 GO:1901979 biolink:BiologicalProcess regulation of inward rectifier potassium channel activity Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity. go-plus.json regulation of Kir channel activity http://purl.obolibrary.org/obo/GO_1901979 UBERON:0003559 biolink:AnatomicalEntity hindbrain arachnoid mater An arachnoid mater that is part of a hindbrain [Automatically generated definition]. go-plus.json hindbrain arachnoid mater of neuraxis|arachnoid mater of neuraxis of hindbrain|arachnoid mater of hindbrain|rhombencephalon arachnoid mater|hindbrain arachnoid|arachnoid of hindbrain http://purl.obolibrary.org/obo/UBERON_0003559 GO:1901976 biolink:BiologicalProcess regulation of cell cycle checkpoint Any process that modulates the frequency, rate or extent of cell cycle checkpoint. go-plus.json regulation of G1/S transition checkpoint|regulation of G1/S checkpoint http://purl.obolibrary.org/obo/GO_1901976 gocheck_do_not_manually_annotate CHEBI:22598 biolink:ChemicalSubstance arabinonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_22598 GO:1901977 biolink:BiologicalProcess negative regulation of cell cycle checkpoint Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint. go-plus.json downregulation of cell cycle checkpoint|negative regulation of G1/S checkpoint|negative regulation of G1/S transition checkpoint|down-regulation of cell cycle checkpoint|inhibition of cell cycle checkpoint|down regulation of cell cycle checkpoint http://purl.obolibrary.org/obo/GO_1901977 gocheck_do_not_manually_annotate CHEBI:22599 biolink:ChemicalSubstance arabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_22599 GO:1901974 biolink:MolecularActivity glycerate transmembrane transporter activity Enables the transfer of glycerate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1901974 GO:0045248 biolink:CellularComponent cytosolic oxoglutarate dehydrogenase complex A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). go-plus.json http://purl.obolibrary.org/obo/GO_0045248 GO:1901975 biolink:BiologicalProcess glycerate transmembrane transport The process in which glycerate is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1901975 GO:0045249 biolink:CellularComponent cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0045249 GO:0045246 biolink:CellularComponent cytosolic tricarboxylic acid cycle enzyme complex Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle. go-plus.json TCA cycle enzyme complex|tricarboxylic acid cycle enzyme complex http://purl.obolibrary.org/obo/GO_0045246 GO:1901972 biolink:BiologicalProcess positive regulation of DNA-5-methylcytosine glycosylase activity Any process that activates or increases the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity. go-plus.json upregulation of DNA-5-methylcytosine glycosylase activity|up regulation of DNA-5-methylcytosine glycosylase activity|activation of DNA-5-methylcytosine glycosylase activity|up-regulation of DNA-5-methylcytosine glycosylase activity http://purl.obolibrary.org/obo/GO_1901972 GO:0045247 biolink:CellularComponent cytosolic electron transfer flavoprotein complex A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors. go-plus.json http://purl.obolibrary.org/obo/GO_0045247 GO:1901973 biolink:MolecularActivity proline binding Binding to proline. go-plus.json http://purl.obolibrary.org/obo/GO_1901973 GO:0045244 biolink:CellularComponent succinate-CoA ligase complex (GDP-forming) A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP. go-plus.json succinyl-CoA synthetase, GDP-forming http://purl.obolibrary.org/obo/GO_0045244 GO:1901970 biolink:BiologicalProcess positive regulation of mitotic sister chromatid separation Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation. go-plus.json up regulation of mitotic sister chromatid separation|up regulation of mitotic chromosome separation|activation of mitotic sister chromatid resolution|activation of mitotic sister chromatid separation|positive regulation of mitotic chromosome separation|up-regulation of sister chromatid separation during mitosis|upregulation of chromosome separation during mitosis|up-regulation of mitotic sister chromatid resolution|activation of mitotic chromosome separation|activation of sister chromatid separation during mitosis|up-regulation of mitotic chromosome separation|up-regulation of mitotic sister chromatid separation|up-regulation of chromosome separation during mitosis|upregulation of mitotic sister chromatid resolution|positive regulation of sister chromatid separation during mitosis|up regulation of sister chromatid separation during mitosis|activation of chromosome separation during mitosis|upregulation of mitotic chromosome separation|upregulation of mitotic sister chromatid separation|positive regulation of chromosome separation during mitosis|up regulation of mitotic sister chromatid resolution|upregulation of sister chromatid separation during mitosis|positive regulation of mitotic sister chromatid resolution|up regulation of chromosome separation during mitosis http://purl.obolibrary.org/obo/GO_1901970 GO:1901971 biolink:BiologicalProcess regulation of DNA-5-methylcytosine glycosylase activity Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1901971 GO:0045245 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045245 CHEBI:22593 biolink:ChemicalSubstance arabinitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22593 GO:0045242 biolink:CellularComponent isocitrate dehydrogenase complex (NAD+) Complex that possesses isocitrate dehydrogenase (NAD+) activity. go-plus.json http://purl.obolibrary.org/obo/GO_0045242 CHEBI:22590 biolink:ChemicalSubstance arabinan go-plus.json http://purl.obolibrary.org/obo/CHEBI_22590 GO:0045243 biolink:CellularComponent cytosolic isocitrate dehydrogenase complex (NAD+) Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity. go-plus.json isocitrate dehydrogenase complex (NAD+) http://purl.obolibrary.org/obo/GO_0045243 UBERON:0003560 biolink:AnatomicalEntity spinal cord arachnoid mater An arachnoid mater that is part of a spinal cord [Automatically generated definition]. go-plus.json arachnoid mater of neuraxis of spinal cord|arachnoid mater of spinal cord|spinal cord arachnoid|arachnoid of spinal cord|spinal cord arachnoid mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0003560 GO:0060860 biolink:BiologicalProcess regulation of floral organ abscission Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs. go-plus.json http://purl.obolibrary.org/obo/GO_0060860 UBERON:0003561 biolink:AnatomicalEntity forebrain dura mater A dura mater that is part of a forebrain. go-plus.json dura mater of neuraxis of forebrain|dura mater of forebrain|forebrain dura mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0003561 GO:0060861 biolink:BiologicalProcess positive regulation of floral organ abscission Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs. go-plus.json http://purl.obolibrary.org/obo/GO_0060861 GO:0060862 biolink:BiologicalProcess negative regulation of floral organ abscission Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs. go-plus.json http://purl.obolibrary.org/obo/GO_0060862 GO:0060863 biolink:BiologicalProcess regulation of floral organ abscission by signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission. go-plus.json http://purl.obolibrary.org/obo/GO_0060863 GO:0060864 biolink:BiologicalProcess obsolete positive regulation of floral organ abscission by small GTPase mediated signal transduction OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission. go-plus.json http://purl.obolibrary.org/obo/GO_0060864 GO:0060865 biolink:BiologicalProcess negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission. go-plus.json negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signalling pathway http://purl.obolibrary.org/obo/GO_0060865 GO:0060866 biolink:BiologicalProcess leaf abscission The controlled shedding of a leaf. go-plus.json http://purl.obolibrary.org/obo/GO_0060866 UBERON:0003568 biolink:AnatomicalEntity neck connective tissue A portion of connective tissue that is part of a neck [Automatically generated definition]. go-plus.json portion of connective tissue of neck|textus connectivus of neck|connective tissue of neck (volume)|neck portion of connective tissue|neck textus connectivus|neck (volume) portion of connective tissue|neck (volume) connective tissue|connective tissue of neck|textus connectivus of neck (volume)|neck (volume) textus connectivus|portion of connective tissue of neck (volume) http://purl.obolibrary.org/obo/UBERON_0003568 GO:0060867 biolink:BiologicalProcess fruit abscission The controlled shedding of a fruit. go-plus.json http://purl.obolibrary.org/obo/GO_0060867 UBERON:0003569 biolink:AnatomicalEntity leg connective tissue A portion of connective tissue that is part of a leg [Automatically generated definition]. go-plus.json connective tissue of leg|textus connectivus of leg|portion of connective tissue of leg|leg portion of connective tissue|leg textus connectivus http://purl.obolibrary.org/obo/UBERON_0003569 GO:0060868 biolink:BiologicalProcess obsolete regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission. go-plus.json http://purl.obolibrary.org/obo/GO_0060868 UBERON:0003566 biolink:AnatomicalEntity head connective tissue A portion of connective tissue that is part of a head [Automatically generated definition]. go-plus.json textus connectivus of adult head|textus connectivus of head|head portion of connective tissue|connective tissue of adult head|adult head portion of connective tissue|connective tissue of head|head textus connectivus|adult head connective tissue|adult head textus connectivus|portion of connective tissue of adult head|portion of connective tissue of head http://purl.obolibrary.org/obo/UBERON_0003566 GO:0060869 biolink:BiologicalProcess transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission. go-plus.json transmembrane receptor protein serine/threonine kinase signalling pathway involved in floral organ abscission http://purl.obolibrary.org/obo/GO_0060869 UBERON:0003567 biolink:AnatomicalEntity abdomen connective tissue A portion of connective tissue that is part of an abdomen [Automatically generated definition]. go-plus.json connective tissue of abdomen|textus connectivus of abdomen|abdomen portion of connective tissue|portion of connective tissue of abdomen|abdomen textus connectivus http://purl.obolibrary.org/obo/UBERON_0003567 UBERON:0003564 biolink:AnatomicalEntity diencephalon dura mater A dura mater that is part of a diencephalon [Automatically generated definition]. go-plus.json dura mater of neuraxis of interbrain|between brain dura mater of neuraxis|dura mater of neuraxis of between brain|dura mater of between brain|dura mater of diencephalon|dura mater of neuraxis of diencephalon|mature diencephalon dura mater|mature diencephalon dura mater of neuraxis|diencephalon dura mater of neuraxis|dura mater of neuraxis of mature diencephalon|dura mater of mature diencephalon|interbrain dura mater|interbrain dura mater of neuraxis|dura mater of interbrain|between brain dura mater http://purl.obolibrary.org/obo/UBERON_0003564 UBERON:0003565 biolink:AnatomicalEntity hindbrain dura mater A dura mater that is part of a hindbrain [Automatically generated definition]. go-plus.json rhombencephalon dura mater|hindbrain dura mater of neuraxis|dura mater of neuraxis of hindbrain|dura mater of hindbrain http://purl.obolibrary.org/obo/UBERON_0003565 UBERON:0003562 biolink:AnatomicalEntity midbrain dura mater A dura mater that is part of a midbrain [Automatically generated definition]. go-plus.json dura mater of midbrain|dura mater of neuraxis of midbrain|mesencephalon dura mater|midbrain dura mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0003562 UBERON:0003563 biolink:AnatomicalEntity telencephalon dura mater A dura mater that is part of a telencephalon [Automatically generated definition]. go-plus.json telencephalon dura mater of neuraxis|dura mater of neuraxis of telencephalon|dura mater of telencephalon http://purl.obolibrary.org/obo/UBERON_0003563 GO:0045251 biolink:CellularComponent electron transfer flavoprotein complex A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system. go-plus.json ETF complex http://purl.obolibrary.org/obo/GO_0045251 goslim_pir CHEBI:22563 biolink:ChemicalSubstance anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22563 GO:0045252 biolink:CellularComponent oxoglutarate dehydrogenase complex A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). go-plus.json dihydrolipoamide S-succinyltransferase complex http://purl.obolibrary.org/obo/GO_0045252 goslim_pir CHEBI:22562 biolink:ChemicalSubstance anilines go-plus.json http://purl.obolibrary.org/obo/CHEBI_22562 GO:0045250 biolink:CellularComponent cytosolic pyruvate dehydrogenase complex Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order. go-plus.json pyruvate dehydrogenase complex (lipoamide) http://purl.obolibrary.org/obo/GO_0045250 NCBITaxon:1292248 biolink:OrganismalEntity Planarioidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1292248 GO:1901989 biolink:BiologicalProcess positive regulation of cell cycle phase transition Any process that activates or increases the frequency, rate or extent of cell cycle phase transition. go-plus.json up regulation of cell cycle phase transition|activation of cell cycle phase transition|up regulation of cell cycle transition|positive regulation of cell cycle transition|activation of cell cycle transition|up-regulation of cell cycle phase transition|up-regulation of cell cycle transition|upregulation of cell cycle phase transition|upregulation of cell cycle transition http://purl.obolibrary.org/obo/GO_1901989 UBERON:0003548 biolink:AnatomicalEntity forebrain meninges A meninx that is part of a forebrain [Automatically generated definition]. go-plus.json forebrain meninx|meninges of forebrain|meninx of forebrain http://purl.obolibrary.org/obo/UBERON_0003548 GO:1901987 biolink:BiologicalProcess regulation of cell cycle phase transition Any process that modulates the frequency, rate or extent of cell cycle phase transition. go-plus.json regulation of cell cycle transition|cell cycle control http://purl.obolibrary.org/obo/GO_1901987 CHEBI:22565 biolink:ChemicalSubstance ansamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22565 GO:1901988 biolink:BiologicalProcess negative regulation of cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition. go-plus.json down regulation of cell cycle transition|downregulation of cell cycle transition|down-regulation of cell cycle phase transition|down-regulation of cell cycle transition|negative regulation of cell cycle transition|inhibition of cell cycle phase transition|inhibition of cell cycle transition|down regulation of cell cycle phase transition|downregulation of cell cycle phase transition http://purl.obolibrary.org/obo/GO_1901988 UBERON:0003549 biolink:AnatomicalEntity brain pia mater The fibrous membrane forming the innermost of the three coverings that surrounds the brain within the cranial cavity that is firmly attached to the glial capsule. go-plus.json brain pia mater of neuraxis|pia mater of neuraxis of brain|pia mater of brain http://purl.obolibrary.org/obo/UBERON_0003549 GO:1901985 biolink:BiologicalProcess positive regulation of protein acetylation Any process that activates or increases the frequency, rate or extent of protein acetylation. go-plus.json upregulation of protein amino acid acetylation|activation of protein acetylation|up-regulation of protein amino acid acetylation|activation of protein amino acid acetylation|up-regulation of protein acetylation|positive regulation of protein amino acid acetylation|upregulation of protein acetylation|up regulation of protein amino acid acetylation|up regulation of protein acetylation http://purl.obolibrary.org/obo/GO_1901985 GO:0045259 biolink:CellularComponent proton-transporting ATP synthase complex A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. go-plus.json F1-F0 complex|hydrogen-translocating F-type ATPase complex|hydrogen-transporting ATP synthase complex|proton-transporting F-type ATPase complex http://purl.obolibrary.org/obo/GO_0045259 GO:1901986 biolink:BiologicalProcess response to ketamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901986 GO:0045257 biolink:CellularComponent succinate dehydrogenase complex (ubiquinone) The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. go-plus.json http://purl.obolibrary.org/obo/GO_0045257 GO:1901983 biolink:BiologicalProcess regulation of protein acetylation Any process that modulates the frequency, rate or extent of protein acetylation. go-plus.json regulation of protein amino acid acetylation http://purl.obolibrary.org/obo/GO_1901983 GO:1901984 biolink:BiologicalProcess negative regulation of protein acetylation Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation. go-plus.json down-regulation of protein acetylation|inhibition of protein acetylation|negative regulation of protein amino acid acetylation|down-regulation of protein amino acid acetylation|down regulation of protein acetylation|downregulation of protein amino acid acetylation|downregulation of protein acetylation|down regulation of protein amino acid acetylation|inhibition of protein amino acid acetylation http://purl.obolibrary.org/obo/GO_1901984 GO:0045258 biolink:CellularComponent plasma membrane succinate dehydrogenase complex (ubiquinone) The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. go-plus.json http://purl.obolibrary.org/obo/GO_0045258 GO:1901981 biolink:MolecularActivity phosphatidylinositol phosphate binding Binding to phosphatidylinositol phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1901981 GO:0045255 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045255 GO:1901982 biolink:MolecularActivity maltose binding Binding to maltose. go-plus.json http://purl.obolibrary.org/obo/GO_1901982 GO:0045256 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045256 GO:0060890 biolink:BiologicalProcess limb spinous cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060890 NCBITaxon:1292243 biolink:OrganismalEntity Continenticola go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1292243 GO:0045253 biolink:CellularComponent pyruvate dehydrogenase (lipoamide) phosphatase complex A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0045253 goslim_pir GO:1901980 biolink:BiologicalProcess positive regulation of inward rectifier potassium channel activity Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity. go-plus.json activation of Kir channel activity|upregulation of inward rectifier potassium channel activity|positive regulation of Kir channel activity|up regulation of Kir channel activity|up regulation of inward rectifier potassium channel activity|activation of inward rectifier potassium channel activity|upregulation of Kir channel activity|up-regulation of Kir channel activity|up-regulation of inward rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_1901980 GO:0045254 biolink:CellularComponent pyruvate dehydrogenase complex Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Wikipedia:Pyruvate_dehydrogenase_complex go-plus.json pyruvate dehydrogenase complex (lipoamide)|dihydrolipoyl dehydrogenase complex http://purl.obolibrary.org/obo/GO_0045254 goslim_pir GO:0060891 biolink:BiologicalProcess limb granular cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060891 GO:0060892 biolink:BiologicalProcess limb basal epidermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0060892 UBERON:0003550 biolink:AnatomicalEntity forebrain pia mater A pia mater that is part of a forebrain [Automatically generated definition]. go-plus.json pia mater of neuraxis of forebrain|pia mater of forebrain|forebrain pia mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0003550 GO:0060893 biolink:BiologicalProcess limb granular cell fate specification The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0060893 GO:0060894 biolink:BiologicalProcess limb spinous cell fate specification The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0060894 GO:0060895 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord. go-plus.json retinoic acid receptor signalling pathway involved in spinal cord dorsal/ventral patterning http://purl.obolibrary.org/obo/GO_0060895 GO:0070219 biolink:BiologicalProcess cellular sulfide ion homeostasis Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell. go-plus.json cellular sulphide homeostasis|cellular sulfide homeostasis|cellular sulphide ion homeostasis http://purl.obolibrary.org/obo/GO_0070219 GO:0060896 biolink:BiologicalProcess neural plate pattern specification The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. go-plus.json http://purl.obolibrary.org/obo/GO_0060896 GO:0060897 biolink:BiologicalProcess neural plate regionalization The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060897 GO:0070217 biolink:BiologicalProcess transcription factor TFIIIB complex assembly The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex. go-plus.json TFIIIB assembly http://purl.obolibrary.org/obo/GO_0070217 GO:0060898 biolink:BiologicalProcess eye field cell fate commitment involved in camera-type eye formation The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode. go-plus.json http://purl.obolibrary.org/obo/GO_0060898 GO:0070218 biolink:BiologicalProcess sulfide ion homeostasis Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell. go-plus.json sulphide production|sulphide generation|sulfide production|sulfide generation|sulphide ion homeostasis|sulfide homeostasis|sulphide homeostasis http://purl.obolibrary.org/obo/GO_0070218 GO:0060899 biolink:BiologicalProcess obsolete regulation of transcription involved in eye field cell fate commitment of camera-type eye OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0060899 UBERON:0003557 biolink:AnatomicalEntity midbrain arachnoid mater An arachnoid mater that is part of a midbrain [Automatically generated definition]. go-plus.json mesencephalon arachnoid mater|midbrain arachnoid|arachnoid mater of midbrain|arachnoid mater of neuraxis of midbrain|midbrain arachnoid mater of neuraxis|arachnoid of midbrain http://purl.obolibrary.org/obo/UBERON_0003557 GO:0070215 biolink:MolecularActivity obsolete MDM2 binding OBSOLETE. Binding to an isoform of the MDM2 protein, a negative regulator of p53. go-plus.json MDM2 binding http://purl.obolibrary.org/obo/GO_0070215 UBERON:0003558 biolink:AnatomicalEntity diencephalon arachnoid mater An arachnoid mater that is part of a diencephalon [Automatically generated definition]. go-plus.json arachnoid mater of interbrain|arachnoid mater of neuraxis of interbrain|between brain arachnoid mater|mature diencephalon arachnoid|between brain arachnoid mater of neuraxis|arachnoid mater of diencephalon|arachnoid mater of neuraxis of between brain|interbrain arachnoid mater|arachnoid mater of between brain|arachnoid mater of neuraxis of diencephalon|interbrain arachnoid mater of neuraxis|arachnoid of interbrain|arachnoid of mature diencephalon|between brain arachnoid|diencephalon arachnoid mater of neuraxis|arachnoid of diencephalon|interbrain arachnoid|mature diencephalon arachnoid mater|mature diencephalon arachnoid mater of neuraxis|arachnoid mater of neuraxis of mature diencephalon|arachnoid of between brain|arachnoid mater of mature diencephalon|diencephalon arachnoid http://purl.obolibrary.org/obo/UBERON_0003558 GO:0070216 biolink:MolecularActivity obsolete MDM4 binding OBSOLETE. Binding to an isoform of the MDM4 protein, a negative regulator of p53. go-plus.json MDMX binding|MDM4 binding http://purl.obolibrary.org/obo/GO_0070216 CHEBI:22569 biolink:ChemicalSubstance anthocyanidin glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_22569 UBERON:0003555 biolink:AnatomicalEntity spinal cord pia mater A pia mater that is part of a spinal cord [Automatically generated definition]. go-plus.json pia mater of neuraxis of spinal cord|pia mater of spinal cord|spinal cord pia mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0003555 GO:0070213 biolink:BiologicalProcess protein auto-ADP-ribosylation The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. go-plus.json protein amino acid auto-ADP-ribosylation http://purl.obolibrary.org/obo/GO_0070213 GO:0070214 biolink:CellularComponent CSK-GAP-A.p62 complex A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation. go-plus.json http://purl.obolibrary.org/obo/GO_0070214 UBERON:0003556 biolink:AnatomicalEntity forebrain arachnoid mater An arachnoid mater that is part of a forebrain [Automatically generated definition]. go-plus.json arachnoid of forebrain|forebrain arachnoid mater of neuraxis|arachnoid mater of neuraxis of forebrain|arachnoid mater of forebrain|forebrain arachnoid http://purl.obolibrary.org/obo/UBERON_0003556 UBERON:0003553 biolink:AnatomicalEntity diencephalon pia mater A pia mater that is part of a diencephalon [Automatically generated definition]. go-plus.json mature diencephalon pia mater|mature diencephalon pia mater of neuraxis|pia mater of interbrain|pia mater of neuraxis of interbrain|between brain pia mater|between brain pia mater of neuraxis|pia mater of diencephalon|interbrain pia mater|pia mater of neuraxis of mature diencephalon|pia mater of neuraxis of diencephalon|interbrain pia mater of neuraxis|pia mater of mature diencephalon|diencephalon pia mater of neuraxis|pia mater of neuraxis of between brain|pia mater of between brain http://purl.obolibrary.org/obo/UBERON_0003553 GO:0070211 biolink:CellularComponent Snt2C complex A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p. go-plus.json http://purl.obolibrary.org/obo/GO_0070211 GO:0070212 biolink:BiologicalProcess protein poly-ADP-ribosylation The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain. go-plus.json addition of poly-ADP-ribose to protein|protein poly(ADP-ribose) synthesis|protein amino acid poly-ADP-ribosylation|poly(ADP-ribose) addition to protein|protein poly(ADP-ribose) metabolism http://purl.obolibrary.org/obo/GO_0070212 UBERON:0003554 biolink:AnatomicalEntity hindbrain pia mater A pia mater that is part of a hindbrain [Automatically generated definition]. go-plus.json hindbrain pia mater of neuraxis|rhombencephalon pia mater|pia mater of neuraxis of hindbrain|pia mater of hindbrain http://purl.obolibrary.org/obo/UBERON_0003554 UBERON:0003551 biolink:AnatomicalEntity midbrain pia mater A pia mater that is part of a midbrain [Automatically generated definition]. go-plus.json mesencephalon pia mater|pia mater of midbrain|pia mater of neuraxis of midbrain|midbrain pia mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0003551 UBERON:0003552 biolink:AnatomicalEntity telencephalon pia mater A pia mater that is part of a telencephalon [Automatically generated definition]. go-plus.json telencephalon pia mater of neuraxis|pia mater of neuraxis of telencephalon|pia mater of telencephalon http://purl.obolibrary.org/obo/UBERON_0003552 GO:0070210 biolink:CellularComponent Rpd3L-Expanded complex A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins. go-plus.json Clr6-LE complex http://purl.obolibrary.org/obo/GO_0070210 GO:0045262 biolink:CellularComponent plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species. go-plus.json hydrogen-transporting ATP synthase, F1 sector|proton-transporting ATP synthase complex, catalytic core F(1) http://purl.obolibrary.org/obo/GO_0045262 GO:0045263 biolink:CellularComponent proton-transporting ATP synthase complex, coupling factor F(o) All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins. go-plus.json proton-transporting ATP synthase complex, coupling factor F(0)|hydrogen-transporting ATP synthase complex, coupling factor F(o)|hydrogen-transporting ATP synthase, F0 sector|hydrogen-transporting ATP synthase, coupling factor CF(0) http://purl.obolibrary.org/obo/GO_0045263 GO:0045260 biolink:CellularComponent plasma membrane proton-transporting ATP synthase complex A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species. go-plus.json hydrogen-translocating F-type ATPase complex|proton-transporting ATP synthase complex|plasma membrane hydrogen-translocating F-type ATPase complex|hydrogen-transporting ATP synthase http://purl.obolibrary.org/obo/GO_0045260 GO:0045261 biolink:CellularComponent proton-transporting ATP synthase complex, catalytic core F(1) The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled. go-plus.json hydrogen-transporting ATP synthase, F1 sector http://purl.obolibrary.org/obo/GO_0045261 UBERON:0003539 biolink:AnatomicalEntity left lung bronchiole A bronchiole that is part of a left lung [Automatically generated definition]. go-plus.json lobular bronchiole of left lung|bronchiole of left lung|left lung lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0003539 GO:1901998 biolink:BiologicalProcess toxin transport The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1901998 GO:1901999 biolink:BiologicalProcess homogentisate metabolic process The chemical reactions and pathways involving homogentisate. go-plus.json homogentisate metabolism http://purl.obolibrary.org/obo/GO_1901999 UBERON:0003538 biolink:AnatomicalEntity right lung bronchiole A bronchiole that is part of a right lung [Automatically generated definition]. go-plus.json bronchiole of right lung|lobular bronchiole of right lung|right lung lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0003538 OBO:GOCHE_76725 biolink:OntologyClass substance with EC 1.* (oxidoreductase) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76725 3_STAR GO:1901996 biolink:BiologicalProcess regulation of indoleacetic acid biosynthetic process via tryptophan Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan. go-plus.json regulation of indoleacetic acid formation via tryptophan|regulation of indoleacetic acid synthesis via tryptophan|regulation of indoleacetic acid anabolism via tryptophan|regulation of IAA biosynthetic process via tryptophan http://purl.obolibrary.org/obo/GO_1901996 GO:1901997 biolink:BiologicalProcess negative regulation of indoleacetic acid biosynthetic process via tryptophan Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan. go-plus.json down-regulation of indoleacetic acid synthesis via tryptophan|negative regulation of indoleacetic acid synthesis via tryptophan|down-regulation of indoleacetic acid biosynthetic process via tryptophan|negative regulation of IAA biosynthetic process via tryptophan|down-regulation of IAA biosynthetic process via tryptophan|down-regulation of indoleacetic acid anabolism via tryptophan|negative regulation of indoleacetic acid anabolism via tryptophan|downregulation of indoleacetic acid formation via tryptophan|inhibition of indoleacetic acid biosynthetic process via tryptophan|downregulation of indoleacetic acid synthesis via tryptophan|down regulation of indoleacetic acid formation via tryptophan|down regulation of indoleacetic acid synthesis via tryptophan|downregulation of indoleacetic acid anabolism via tryptophan|inhibition of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid anabolism via tryptophan|inhibition of indoleacetic acid formation via tryptophan|inhibition of indoleacetic acid synthesis via tryptophan|down regulation of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid biosynthetic process via tryptophan|inhibition of indoleacetic acid anabolism via tryptophan|downregulation of IAA biosynthetic process via tryptophan|downregulation of indoleacetic acid biosynthetic process via tryptophan|down-regulation of indoleacetic acid formation via tryptophan|negative regulation of indoleacetic acid formation via tryptophan http://purl.obolibrary.org/obo/GO_1901997 GO:0045268 biolink:CellularComponent plasma membrane proton-transporting ATP synthase, catalytic core The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species. go-plus.json proton-transporting ATP synthase, catalytic core|hydrogen-transporting ATP synthase, catalytic core http://purl.obolibrary.org/obo/GO_0045268 GO:1901994 biolink:BiologicalProcess negative regulation of meiotic cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition. go-plus.json negative regulation of cell cycle transition|down-regulation of meiotic cell cycle phase transition|down-regulation of cell cycle transition|inhibition of meiotic cell cycle phase transition|inhibition of cell cycle transition|down regulation of cell cycle transition|down regulation of meiotic cell cycle phase transition|downregulation of cell cycle transition|downregulation of meiotic cell cycle phase transition http://purl.obolibrary.org/obo/GO_1901994 GO:0045269 biolink:CellularComponent proton-transporting ATP synthase, central stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis. go-plus.json hydrogen-transporting ATP synthase, central stalk http://purl.obolibrary.org/obo/GO_0045269 GO:1901995 biolink:BiologicalProcess positive regulation of meiotic cell cycle phase transition Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition. go-plus.json positive regulation of cell cycle transition|activation of meiotic cell cycle phase transition|activation of cell cycle transition|up-regulation of cell cycle transition|up-regulation of meiotic cell cycle phase transition|upregulation of meiotic cell cycle phase transition|upregulation of cell cycle transition|up regulation of cell cycle transition|up regulation of meiotic cell cycle phase transition http://purl.obolibrary.org/obo/GO_1901995 GO:1901992 biolink:BiologicalProcess positive regulation of mitotic cell cycle phase transition Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition. go-plus.json up-regulation of mitotic cell cycle phase transition|upregulation of mitotic cell cycle phase transition|up regulation of mitotic cell cycle phase transition|activation of mitotic cell cycle phase transition http://purl.obolibrary.org/obo/GO_1901992 GO:0045266 biolink:CellularComponent plasma membrane proton-transporting ATP synthase, stator stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species. go-plus.json proton-transporting ATP synthase, stator stalk|hydrogen-transporting ATP synthase, stator stalk http://purl.obolibrary.org/obo/GO_0045266 GO:0045267 biolink:CellularComponent proton-transporting ATP synthase, catalytic core The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase. go-plus.json hydrogen-transporting ATP synthase, catalytic core http://purl.obolibrary.org/obo/GO_0045267 GO:1901993 biolink:BiologicalProcess regulation of meiotic cell cycle phase transition Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition. go-plus.json meiotic cell cycle control|regulation of cell cycle transition http://purl.obolibrary.org/obo/GO_1901993 GO:0045264 biolink:CellularComponent plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins. go-plus.json hydrogen-transporting ATP synthase, F0 sector|proton-transporting ATP synthase complex, coupling factor F(o)|proton-transporting ATP synthase complex, coupling factor F(0) http://purl.obolibrary.org/obo/GO_0045264 GO:1901990 biolink:BiologicalProcess regulation of mitotic cell cycle phase transition Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition. go-plus.json mitotic cell cycle control http://purl.obolibrary.org/obo/GO_1901990 GO:1901991 biolink:BiologicalProcess negative regulation of mitotic cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition. go-plus.json inhibition of mitotic cell cycle phase transition|down regulation of mitotic cell cycle phase transition|downregulation of mitotic cell cycle phase transition|down-regulation of mitotic cell cycle phase transition http://purl.obolibrary.org/obo/GO_1901991 GO:0045265 biolink:CellularComponent proton-transporting ATP synthase, stator stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core. go-plus.json hydrogen-transporting ATP synthase, stator stalk http://purl.obolibrary.org/obo/GO_0045265 GO:0060880 biolink:BiologicalProcess cell morphogenesis involved in semicircular canal fusion The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0060880 GO:0060881 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060881 GO:0060882 biolink:BiologicalProcess basement membrane disassembly involved in semicircular canal fusion A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion. go-plus.json basal lamina disassembly involved in semicircular canal fusion http://purl.obolibrary.org/obo/GO_0060882 GO:0060883 biolink:BiologicalProcess regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basement membrane disassembly involved in semicircular canal fusion. go-plus.json regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication http://purl.obolibrary.org/obo/GO_0060883 GO:0060884 biolink:BiologicalProcess clearance of cells from fusion plate The morphogenetic process in which cells are removed from the inner loop of a semicircular canal. go-plus.json http://purl.obolibrary.org/obo/GO_0060884 GO:0070208 biolink:BiologicalProcess protein heterotrimerization The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical. go-plus.json protein heterotrimer formation|protein heterotrimer biosynthesis|protein heterotrimer biosynthetic process|protein heterotrimer assembly http://purl.obolibrary.org/obo/GO_0070208 GO:0060885 biolink:BiologicalProcess clearance of cells from fusion plate by apoptotic process Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals. go-plus.json clearance of cells from fusion plate by apoptosis http://purl.obolibrary.org/obo/GO_0060885 GO:0060886 biolink:BiologicalProcess clearance of cells from fusion plate by epithelial to mesenchymal transition The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals. go-plus.json http://purl.obolibrary.org/obo/GO_0060886 GO:0070209 biolink:CellularComponent ASTRA complex A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p. go-plus.json http://purl.obolibrary.org/obo/GO_0070209 GO:0070206 biolink:BiologicalProcess protein trimerization The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits. go-plus.json protein trimer biosynthetic process|protein trimer biosynthesis|protein trimer formation|protein trimer assembly http://purl.obolibrary.org/obo/GO_0070206 GO:0060887 biolink:BiologicalProcess limb epidermis development The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0060887 GO:0060888 biolink:BiologicalProcess limb epidermis stratification The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0060888 GO:0070207 biolink:BiologicalProcess protein homotrimerization The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits. go-plus.json protein homotrimer formation|protein homotrimer biosynthesis|protein homotrimer biosynthetic process|protein homotrimer assembly http://purl.obolibrary.org/obo/GO_0070207 GO:0060889 biolink:BiologicalProcess limb basal epidermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0060889 GO:0070204 biolink:MolecularActivity 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2). EC:2.2.1.9|RHEA:25593|KEGG_REACTION:R08165|MetaCyc:2.5.1.64-RXN go-plus.json MenD|SEPHCHC synthase activity http://purl.obolibrary.org/obo/GO_0070204 UBERON:0003546 biolink:AnatomicalEntity distal convoluted tubule macula densa A macula densa that is part of a distal convoluted tubule [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003546 GO:0070205 biolink:MolecularActivity 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate. MetaCyc:RXN-9310|RHEA:25597|KEGG_REACTION:R08166|EC:4.2.99.20 go-plus.json 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity|SHCHC synthase activity|6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity|MenH|YfbB http://purl.obolibrary.org/obo/GO_0070205 UBERON:0003547 biolink:AnatomicalEntity brain meninx A meninx that is part of a brain [Automatically generated definition]. go-plus.json meninges of brain|meninx of brain|brain meninges http://purl.obolibrary.org/obo/UBERON_0003547 UBERON:0003544 biolink:AnatomicalEntity brain white matter The regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. go-plus.json brain white substance|brain white matter of neuraxis|white matter of neuraxis of brain|white matter of brain|white substance of brain http://purl.obolibrary.org/obo/UBERON_0003544 GO:0070202 biolink:BiologicalProcess regulation of establishment of protein localization to chromosome Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. go-plus.json regulation of establishment of protein localisation to chromosome http://purl.obolibrary.org/obo/GO_0070202 GO:0070203 biolink:BiologicalProcess regulation of establishment of protein localization to telomere Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome. go-plus.json regulation of establishment of protein localisation to telomere http://purl.obolibrary.org/obo/GO_0070203 GO:0070200 biolink:BiologicalProcess establishment of protein localization to telomere The directed movement of a protein to a specific location in the telomeric region of a chromosome. go-plus.json establishment of protein localization to chromosome, telomeric region|establishment of protein localisation to telomere http://purl.obolibrary.org/obo/GO_0070200 GO:0070201 biolink:BiologicalProcess regulation of establishment of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. go-plus.json regulation of establishment of protein localisation http://purl.obolibrary.org/obo/GO_0070201 UBERON:0003540 biolink:AnatomicalEntity right lung terminal bronchiole A terminal bronchiole that is part of a right lung [Automatically generated definition]. go-plus.json right lung bronchiolus terminalis|terminal bronchiole of right lung|bronchiolus terminalis of right lung http://purl.obolibrary.org/obo/UBERON_0003540 UBERON:0003541 biolink:AnatomicalEntity left lung terminal bronchiole A terminal bronchiole that is part of a left lung [Automatically generated definition]. go-plus.json bronchiolus terminalis of left lung|left lung bronchiolus terminalis|terminal bronchiole of left lung http://purl.obolibrary.org/obo/UBERON_0003541 GO:0045273 biolink:CellularComponent respiratory chain complex II A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. go-plus.json electron transport complex II http://purl.obolibrary.org/obo/GO_0045273 goslim_pir GO:0045274 biolink:CellularComponent plasma membrane respiratory chain complex II A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species. go-plus.json respiratory chain complex II http://purl.obolibrary.org/obo/GO_0045274 GO:0070230 biolink:BiologicalProcess positive regulation of lymphocyte apoptotic process Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. go-plus.json up regulation of lymphocyte apoptosis|positive regulation of lymphocyte apoptosis|upregulation of lymphocyte apoptosis|stimulation of lymphocyte apoptosis|up-regulation of lymphocyte apoptosis|activation of lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_0070230 CHEBI:22542 biolink:ChemicalSubstance androstane-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_22542 chebi_ph7_3 GO:0045271 biolink:CellularComponent respiratory chain complex I Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex. go-plus.json NADH-Q oxidoreductase complex|NADH dehydrogenase (ubiquinone) complex|NADH dehydrogenase complex (ubiquinone)|electron transport complex I http://purl.obolibrary.org/obo/GO_0045271 GO:0045272 biolink:CellularComponent plasma membrane respiratory chain complex I A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species. go-plus.json NADH dehydrogenase (ubiquinone) complex|respiratory chain complex I http://purl.obolibrary.org/obo/GO_0045272 GO:0045270 biolink:CellularComponent plasma membrane proton-transporting ATP synthase, central stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species. go-plus.json hydrogen-transporting ATP synthase, central stalk|proton-transporting ATP synthase, central stalk http://purl.obolibrary.org/obo/GO_0045270 GO:0045279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045279 GO:0045277 biolink:CellularComponent respiratory chain complex IV A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). go-plus.json electron transport complex IV|cytochrome c oxidase complex http://purl.obolibrary.org/obo/GO_0045277 goslim_pir GO:0045278 biolink:CellularComponent plasma membrane respiratory chain complex IV A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species. go-plus.json respiratory chain complex IV|cytochrome c oxidase complex http://purl.obolibrary.org/obo/GO_0045278 GO:0045275 biolink:CellularComponent respiratory chain complex III A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species. Wikipedia:Coenzyme_Q_-_cytochrome_c_reductase go-plus.json CoQH2-cytochrome c reductase complex|cytochrome bc1 complex|ubiquinol-cytochrome c oxidoreductase complex|coenzyme Q-cytochrome c reductase complex|coenzyme Q-cytochrome c oxidoreductase complex|electron transport complex III|ubiquinol-cytochrome-c reductase complex|cytochrome bc(1) complex|complex III http://purl.obolibrary.org/obo/GO_0045275 goslim_pir GO:0045276 biolink:CellularComponent plasma membrane respiratory chain complex III A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species. go-plus.json respiratory chain complex III|plasma membrane coenzyme Q-cytochrome c oxidoreductase complex|ubiquinol-cytochrome-c reductase complex|plasma membrane ubiquinol-cytochrome-c reductase complex|ubiquinol-cytochrome c oxidoreductase complex|plasma membrane coenzyme Q-cytochrome c reductase complex|plasma membrane cytochrome bc1 complex http://purl.obolibrary.org/obo/GO_0045276 GO:0070239 biolink:BiologicalProcess regulation of activated T cell autonomous cell death Any process that modulates the occurrence or rate of activated T cell autonomous cell death. go-plus.json regulation of activated T lymphocyte autonomous cell death|regulation of ACAD|regulation of activated T-cell autonomous cell death|regulation of activated T-lymphocyte autonomous cell death|regulation of activated cell autonomous cell death|regulation of activated T cell apoptosis http://purl.obolibrary.org/obo/GO_0070239 GO:0070237 biolink:BiologicalProcess positive regulation of activation-induced cell death of T cells Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells. go-plus.json up regulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-lymphocytes|upregulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-cells|positive regulation of antigen-driven apoptosis|stimulation of activation-induced cell death of T cells|up-regulation of activation-induced cell death of T cells|activation of activation-induced cell death of T cells|positive regulation of activated T cell apoptosis|positive regulation of activation-induced cell death of T lymphocytes|positive regulation of AICD http://purl.obolibrary.org/obo/GO_0070237 GO:0070238 biolink:BiologicalProcess activated T cell autonomous cell death A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products. go-plus.json activated T-cell autonomous cell death|activated T-lymphocyte autonomous cell death|activated cell autonomous cell death|activated T cell apoptosis|activated T lymphocyte autonomous cell death|ACAD http://purl.obolibrary.org/obo/GO_0070238 GO:0070235 biolink:BiologicalProcess regulation of activation-induced cell death of T cells Any process that modulates the occurrence or rate of activation-induced cell death of T cells. go-plus.json regulation of activation-induced cell death of T lymphocytes|regulation of AICD|regulation of activation-induced cell death of T-lymphocytes|regulation of activation-induced cell death of T-cells|regulation of antigen-driven apoptosis|regulation of activated T cell apoptosis http://purl.obolibrary.org/obo/GO_0070235 GO:0070236 biolink:BiologicalProcess negative regulation of activation-induced cell death of T cells Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells. go-plus.json downregulation of activation-induced cell death of T cells|negative regulation of activation-induced cell death of T-lymphocytes|down regulation of activation-induced cell death of T cells|negative regulation of activation-induced cell death of T-cells|inhibition of activation-induced cell death of T cells|negative regulation of activated T cell apoptosis|negative regulation of activation-induced cell death of T lymphocytes|negative regulation of AICD|down-regulation of activation-induced cell death of T cells|negative regulation of antigen-driven apoptosis http://purl.obolibrary.org/obo/GO_0070236 GO:0070233 biolink:BiologicalProcess negative regulation of T cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process. go-plus.json negative regulation of T cell apoptosis|down regulation of T cell apoptosis|inhibition of T cell apoptosis|negative regulation of T-cell apoptosis|negative regulation of T-lymphocyte apoptosis|down-regulation of T cell apoptosis|negative regulation of programmed cell death of T cells by apoptosis|negative regulation of T lymphocyte apoptosis|downregulation of T cell apoptosis http://purl.obolibrary.org/obo/GO_0070233 GO:0070234 biolink:BiologicalProcess positive regulation of T cell apoptotic process Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process. go-plus.json positive regulation of T cell apoptosis|upregulation of T cell apoptosis|stimulation of T cell apoptosis|positive regulation of T-cell apoptosis|up-regulation of T cell apoptosis|activation of T cell apoptosis|positive regulation of T-lymphocyte apoptosis|positive regulation of programmed cell death of T cells by apoptosis|up regulation of T cell apoptosis|positive regulation of T lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_0070234 GO:0070231 biolink:BiologicalProcess T cell apoptotic process Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. go-plus.json T-cell apoptosis|T-lymphocyte apoptosis|T lymphocyte apoptosis|programmed cell death of T cells by apoptosis|T cell apoptosis http://purl.obolibrary.org/obo/GO_0070231 GO:0070232 biolink:BiologicalProcess regulation of T cell apoptotic process Any process that modulates the occurrence or rate of T cell death by apoptotic process. go-plus.json regulation of T lymphocyte apoptosis|regulation of T cell apoptosis|regulation of programmed cell death of T cells by apoptosis|regulation of T-cell apoptosis|regulation of T-lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_0070232 GO:0045284 biolink:CellularComponent plasma membrane fumarate reductase complex A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species. go-plus.json fumarate reductase complex http://purl.obolibrary.org/obo/GO_0045284 GO:0045285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045285 GO:0045282 biolink:CellularComponent plasma membrane succinate dehydrogenase complex A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species. go-plus.json succinate dehydrogenase complex http://purl.obolibrary.org/obo/GO_0045282 GO:0045283 biolink:CellularComponent fumarate reductase complex A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). go-plus.json http://purl.obolibrary.org/obo/GO_0045283 GO:0045280 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045280 GO:0045281 biolink:CellularComponent succinate dehydrogenase complex A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones. go-plus.json http://purl.obolibrary.org/obo/GO_0045281 CHEBI:22557 biolink:ChemicalSubstance anhydrohexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_22557 CHEBI:46502 biolink:ChemicalSubstance tungstate go-plus.json http://purl.obolibrary.org/obo/CHEBI_46502 chebi_ph7_3 GO:0045288 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045288 GO:0045289 biolink:MolecularActivity luciferin monooxygenase activity Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation. go-plus.json luciferase activity|luciferase monooxygenase activity http://purl.obolibrary.org/obo/GO_0045289 GO:0045286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045286 GO:0045287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045287 GO:0070228 biolink:BiologicalProcess regulation of lymphocyte apoptotic process Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process. go-plus.json regulation of lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_0070228 GO:0070229 biolink:BiologicalProcess negative regulation of lymphocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process. go-plus.json downregulation of lymphocyte apoptosis|negative regulation of lymphocyte apoptosis|down regulation of lymphocyte apoptosis|inhibition of lymphocyte apoptosis|down-regulation of lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_0070229 GO:0070226 biolink:MolecularActivity sulfur:ferric ion oxidoreductase activity Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+. MetaCyc:SULFFEOXIDO-RXN go-plus.json hydrogen sulfide:ferric ion oxidoreductase http://purl.obolibrary.org/obo/GO_0070226 GO:0070227 biolink:BiologicalProcess lymphocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. go-plus.json lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_0070227 GO:0070224 biolink:MolecularActivity sulfide:quinone oxidoreductase activity Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone. RHEA:30239|MetaCyc:R17-RXN|Reactome:R-HSA-1614665 go-plus.json sulphide:quinone oxidoreductase activity|sulfide-quinone reductase activity http://purl.obolibrary.org/obo/GO_0070224 CHEBI:22558 biolink:ChemicalSubstance anhydro sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_22558 GO:0070225 biolink:MolecularActivity sulfide dehydrogenase activity Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c. MetaCyc:RXN-8156|RHEA:30223|EC:1.8.2.3 go-plus.json sulphide dehydrogenase activity|flavocytochrome c sulfide dehydrogenase activity http://purl.obolibrary.org/obo/GO_0070225 GO:0070222 biolink:BiologicalProcess sulfide oxidation, using sulfide dehydrogenase A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase. MetaCyc:PWY-5274 go-plus.json sulphide oxidation, using sulfide dehydrogenase http://purl.obolibrary.org/obo/GO_0070222 GO:0070223 biolink:BiologicalProcess sulfide oxidation, using sulfur dioxygenase A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase. MetaCyc:PWY-5285 go-plus.json sulphide oxidation, using sulfur dioxygenase http://purl.obolibrary.org/obo/GO_0070223 GO:0070220 biolink:BiologicalProcess aerobic sulfur oxidation A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen. MetaCyc:SULFUROX-PWY go-plus.json aerobic sulphur oxidation http://purl.obolibrary.org/obo/GO_0070220 GO:0070221 biolink:BiologicalProcess sulfide oxidation, using sulfide:quinone oxidoreductase A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase. MetaCyc:P222-PWY go-plus.json sulphide oxidation, using sulfide:quinone oxidoreductase|sulfide oxidation, using sulfide-quinone reductase http://purl.obolibrary.org/obo/GO_0070221 GO:0045295 biolink:MolecularActivity gamma-catenin binding Binding to catenin complex gamma subunit. go-plus.json plakoglobin binding http://purl.obolibrary.org/obo/GO_0045295 GO:0070251 biolink:MolecularActivity pristanate-CoA ligase activity Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA. RHEA:47264|Reactome:R-HSA-389632 go-plus.json pristanoyl-CoA ligase activity|pristanate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0070251 GO:0045296 biolink:MolecularActivity cadherin binding Binding to cadherin, a type I membrane protein involved in cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0045296 GO:0070252 biolink:BiologicalProcess actin-mediated cell contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. go-plus.json http://purl.obolibrary.org/obo/GO_0070252 GO:0045293 biolink:CellularComponent mRNA editing complex A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes. go-plus.json editosome http://purl.obolibrary.org/obo/GO_0045293 goslim_pir GO:0045294 biolink:MolecularActivity alpha-catenin binding Binding to catenin complex alpha subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0045294 GO:0070250 biolink:CellularComponent mating projection membrane The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone. go-plus.json shmoo membrane http://purl.obolibrary.org/obo/GO_0070250 GO:0045291 biolink:BiologicalProcess mRNA trans splicing, SL addition The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body. go-plus.json nuclear mRNA trans splicing, spliced leader addition|nuclear mRNA trans splicing, SL addition http://purl.obolibrary.org/obo/GO_0045291 GO:0045292 biolink:BiologicalProcess mRNA cis splicing, via spliceosome The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. go-plus.json splicing|nuclear mRNA cis splicing, via spliceosome|nuclear mRNA cis splicing, via U2-type spliceosome http://purl.obolibrary.org/obo/GO_0045292 GO:0045290 biolink:MolecularActivity D-arabinose 1-dehydrogenase [NAD(P)+] activity Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+. MetaCyc:1.1.1.117-RXN|EC:1.1.1.117 go-plus.json D-arabinose:NAD(P)+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0045290 GO:0045299 biolink:BiologicalProcess otolith mineralization The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear. go-plus.json http://purl.obolibrary.org/obo/GO_0045299 CHEBI:356416 biolink:ChemicalSubstance 5-ammoniolevulinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_356416 chebi_ph7_3 GO:0045297 biolink:BiologicalProcess obsolete post-mating behavior OBSOLETE. The specific behavior of an organism following mating. go-plus.json post-mating behaviour http://purl.obolibrary.org/obo/GO_0045297 GO:0045298 biolink:CellularComponent tubulin complex A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0045298 UBERON:0003593 biolink:AnatomicalEntity thoracic cavity connective tissue A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]. go-plus.json textus connectivus of cavity of thorax|connective tissue of chest cavity|cavity of thorax textus connectivus|portion of connective tissue of thoracic cavity|chest cavity portion of connective tissue|portion of connective tissue of cavity of chest|portion of connective tissue of pectoral cavity|connective tissue of cavity of thorax|chest cavity connective tissue|chest cavity textus connectivus|pectoral cavity portion of connective tissue|portion of connective tissue of chest cavity|cavity of chest portion of connective tissue|thoracic cavity portion of connective tissue|cavity of thorax connective tissue|connective tissue of thoracic cavity|connective tissue of pectoral cavity|connective tissue of cavity of chest|cavity of chest textus connectivus|pectoral cavity textus connectivus|textus connectivus of chest cavity|portion of connective tissue of cavity of thorax|thoracic cavity textus connectivus|textus connectivus of thoracic cavity|cavity of thorax portion of connective tissue|pectoral cavity connective tissue|cavity of chest connective tissue|textus connectivus of cavity of chest|textus connectivus of pectoral cavity http://purl.obolibrary.org/obo/UBERON_0003593 UBERON:0003594 biolink:AnatomicalEntity pelvis connective tissue A portion of connective tissue that is part of a pelvis [Automatically generated definition]. go-plus.json pelvis textus connectivus|textus connectivus of pelvis|connective tissue of pelvis|pelvis portion of connective tissue|portion of connective tissue of pelvis http://purl.obolibrary.org/obo/UBERON_0003594 UBERON:0003591 biolink:AnatomicalEntity lobar bronchus connective tissue A portion of connective tissue that is part of a lobar bronchus [Automatically generated definition]. go-plus.json connective tissue of lobar bronchus|connective tissue of secondary bronchus http://purl.obolibrary.org/obo/UBERON_0003591 UBERON:0003592 biolink:AnatomicalEntity bronchus connective tissue A portion of connective tissue that is part of a bronchus [Automatically generated definition]. go-plus.json connective tissue of bronchi|bronchus portion of connective tissue|connective tissue of bronchial trunk|bronchial trunk portion of connective tissue|bronchial connective tissue|connective tissue of bronchus|bronchi portion of connective tissue|bronchus textus connectivus|textus connectivus of bronchi|bronchial trunk textus connectivus|bronchi connective tissue|bronchial trunk connective tissue|bronchi textus connectivus|textus connectivus of bronchial trunk|portion of connective tissue of bronchi|portion of connective tissue of bronchial trunk|bronchial mesenchyme|portion of connective tissue of bronchus|textus connectivus of bronchus http://purl.obolibrary.org/obo/UBERON_0003592 CHEBI:22527 biolink:ChemicalSubstance aminopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22527 GO:0070259 biolink:MolecularActivity tyrosyl-DNA phosphodiesterase activity Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0070259 UBERON:0003599 biolink:AnatomicalEntity tail connective tissue A portion of connective tissue that is part of a tail [Automatically generated definition]. go-plus.json textus connectivus of tail|tail portion of connective tissue|post-vent region portion of connective tissue|connective tissue of post-vent region|tail textus connectivus|connective tissue of tail|post-vent region textus connectivus|post-vent region connective tissue|portion of connective tissue of post-vent region|portion of connective tissue of tail|textus connectivus of post-vent region http://purl.obolibrary.org/obo/UBERON_0003599 GO:0070257 biolink:BiologicalProcess positive regulation of mucus secretion Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. go-plus.json positive regulation of mucus production http://purl.obolibrary.org/obo/GO_0070257 GO:0070258 biolink:CellularComponent inner membrane pellicle complex A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell. go-plus.json inner membrane complex http://purl.obolibrary.org/obo/GO_0070258 UBERON:0003597 biolink:AnatomicalEntity manual digit connective tissue A portion of connective tissue that is part of a finger [Automatically generated definition]. go-plus.json hand digit connective tissue|hand digit connective tissue|connective tissue of finger|connective tissue of digit of hand|connective tissue of digitus manus|connective tissue of hand digit|fore limb digit connective tissue http://purl.obolibrary.org/obo/UBERON_0003597 GO:0070255 biolink:BiologicalProcess regulation of mucus secretion Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. go-plus.json regulation of mucus production http://purl.obolibrary.org/obo/GO_0070255 UBERON:0003598 biolink:AnatomicalEntity manus connective tissue A portion of connective tissue that is part of a hand [Automatically generated definition]. go-plus.json connective tissue of hand|connective tissue of terminal segment of free upper limb|hand connective tissue http://purl.obolibrary.org/obo/UBERON_0003598 GO:0070256 biolink:BiologicalProcess negative regulation of mucus secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. go-plus.json negative regulation of mucus production http://purl.obolibrary.org/obo/GO_0070256 CHEBI:22529 biolink:ChemicalSubstance amino sugar phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22529 UBERON:0003595 biolink:AnatomicalEntity pes connective tissue A portion of connective tissue that is part of a foot [Automatically generated definition]. go-plus.json textus connectivus of pes|connective tissue of foot|connective tissue of terminal segment of free lower limb|foot connective tissue http://purl.obolibrary.org/obo/UBERON_0003595 GO:0070253 biolink:BiologicalProcess somatostatin secretion The regulated release of somatostatin from secretory granules in the D cells of the pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_0070253 UBERON:0003596 biolink:AnatomicalEntity ankle connective tissue A portion of connective tissue that is part of an ankle [Automatically generated definition]. go-plus.json connective tissue of ankle|tarsal region connective tissue http://purl.obolibrary.org/obo/UBERON_0003596 GO:0070254 biolink:BiologicalProcess mucus secretion The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. go-plus.json mucus production http://purl.obolibrary.org/obo/GO_0070254 GO:0070240 biolink:BiologicalProcess negative regulation of activated T cell autonomous cell death Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death. go-plus.json negative regulation of activated T lymphocyte autonomous cell death|negative regulation of ACAD|downregulation of activated T cell autonomous cell death|down regulation of activated T cell autonomous cell death|inhibition of activated T cell autonomous cell death|negative regulation of activated T-cell autonomous cell death|negative regulation of activated cell autonomous cell death|negative regulation of activated T-lymphocyte autonomous cell death|negative regulation of activated T cell apoptosis|down-regulation of activated T cell autonomous cell death http://purl.obolibrary.org/obo/GO_0070240 GO:0070241 biolink:BiologicalProcess positive regulation of activated T cell autonomous cell death Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death. go-plus.json positive regulation of activated T cell apoptosis|up regulation of activated T cell autonomous cell death|positive regulation of activated T lymphocyte autonomous cell death|positive regulation of ACAD|upregulation of activated T cell autonomous cell death|stimulation of activated T cell autonomous cell death|positive regulation of activated T-cell autonomous cell death|activation of activated T cell autonomous cell death|up-regulation of activated T cell autonomous cell death|positive regulation of activated cell autonomous cell death|positive regulation of activated T-lymphocyte autonomous cell death http://purl.obolibrary.org/obo/GO_0070241 CHEBI:22532 biolink:ChemicalSubstance aminouracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_22532 UBERON:0003582 biolink:AnatomicalEntity nasopharynx connective tissue A portion of connective tissue that is part of a nasopharynx [Automatically generated definition]. go-plus.json connective tissue of nasal part of pharynx|connective tissue of rhinopharynx|textus connectivus of nasopharynx|rhinopharynx portion of connective tissue|nasal part of pharynx connective tissue|textus connectivus of nasal part of pharynx|nasal part of pharynx portion of connective tissue|rhinopharynx connective tissue|nasopharynx portion of connective tissue|portion of connective tissue of nasopharynx|rhinopharynx textus connectivus|portion of connective tissue of nasal part of pharynx|nasal part of pharynx textus connectivus|portion of connective tissue of rhinopharynx|nasopharynx textus connectivus|textus connectivus of rhinopharynx|connective tissue of nasopharynx http://purl.obolibrary.org/obo/UBERON_0003582 UBERON:0003583 biolink:AnatomicalEntity larynx connective tissue A portion of connective tissue that is part of a larynx [Automatically generated definition]. go-plus.json connective tissue of larynx|larynx portion of connective tissue|larynx textus connectivus|portion of connective tissue of larynx|textus connectivus of larynx|laryngeal connective tissue http://purl.obolibrary.org/obo/UBERON_0003583 UBERON:0003580 biolink:AnatomicalEntity lower respiratory tract connective tissue A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]. go-plus.json lower respiratory tract portion of connective tissue|lower respiratory tract textus connectivus|connective tissue of lower respiratory tract|textus connectivus of lower respiratory tract|portion of connective tissue of lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0003580 UBERON:0003581 biolink:AnatomicalEntity eyelid connective tissue A portion of connective tissue that is part of a eyelid [Automatically generated definition]. go-plus.json connective tissue of blepharon|blepharon connective tissue|connective tissue of eyelid http://purl.obolibrary.org/obo/UBERON_0003581 NCBITaxon:9347 biolink:OrganismalEntity Eutheria go-plus.json placental mammals|Placentalia|placentals|eutherian mammals|placentals http://purl.obolibrary.org/obo/NCBITaxon_9347 GO:0070248 biolink:BiologicalProcess negative regulation of natural killer cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process. go-plus.json down regulation of natural killer cell apoptosis|downregulation of natural killer cell apoptosis|negative regulation of NK cell apoptosis|down-regulation of natural killer cell apoptosis|inhibition of natural killer cell apoptosis|negative regulation of natural killer cell apoptosis http://purl.obolibrary.org/obo/GO_0070248 SO:0002308 biolink:SequenceFeature DNA_loop_anchor The ends of a DNA loop where the two strands of DNA are held in close physical proximity. During interphase the anchors of DNA loops are convergently oriented CTCF binding sites. go-plus.json DNA loop anchor http://purl.obolibrary.org/obo/SO_0002308 SO:0002309 biolink:SequenceFeature core_promoter_element An element that always exists within the promoter region of a gene. When multiple transcripts exist for a gene, the separate transcripts may have separate core_promoter_elements. go-plus.json core promoter element http://purl.obolibrary.org/obo/SO_0002309 GO:0070249 biolink:BiologicalProcess positive regulation of natural killer cell apoptotic process Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process. go-plus.json upregulation of natural killer cell apoptosis|positive regulation of NK cell apoptosis|up regulation of natural killer cell apoptosis|activation of natural killer cell apoptosis|stimulation of natural killer cell apoptosis|up-regulation of natural killer cell apoptosis|positive regulation of natural killer cell apoptosis http://purl.obolibrary.org/obo/GO_0070249 UBERON:0003588 biolink:AnatomicalEntity forelimb connective tissue A portion of connective tissue that is part of a forelimb [Automatically generated definition]. go-plus.json connective tissue of superior member|wing connective tissue|connective tissue of upper extremity|connective tissue of anteriormost limb|connective tissue of fore limb|connective tissue of forelimb http://purl.obolibrary.org/obo/UBERON_0003588 GO:0070246 biolink:BiologicalProcess natural killer cell apoptotic process Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation. go-plus.json NK cell apoptosis|natural killer cell apoptosis http://purl.obolibrary.org/obo/GO_0070246 UBERON:0003589 biolink:AnatomicalEntity hindlimb connective tissue A portion of connective tissue that is part of a hindlimb [Automatically generated definition]. go-plus.json connective tissue of hindlimb|connective tissue of inferior member|connective tissue of hind limb|connective tissue of lower extremity|hind limb connective tissue http://purl.obolibrary.org/obo/UBERON_0003589 GO:0070247 biolink:BiologicalProcess regulation of natural killer cell apoptotic process Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process. go-plus.json regulation of natural killer cell apoptosis|regulation of NK cell apoptosis http://purl.obolibrary.org/obo/GO_0070247 SO:0002307 biolink:SequenceFeature DNA_loop A region of DNA between two loop anchor positions that are held in close physical proximity. go-plus.json DNA loop http://purl.obolibrary.org/obo/SO_0002307 UBERON:0003586 biolink:AnatomicalEntity trunk connective tissue A portion of connective tissue that is part of a trunk [Automatically generated definition]. go-plus.json textus connectivus of trunk|torso connective tissue|textus connectivus of torso|portion of connective tissue of trunk|portion of connective tissue of torso|connective tissue of trunk|torso portion of connective tissue|trunk portion of connective tissue|connective tissue of torso|torso textus connectivus|trunk textus connectivus http://purl.obolibrary.org/obo/UBERON_0003586 SO:0002304 biolink:SequenceFeature topologically_associated_domain An instance of a self-interacting DNA region flanked by left and right TAD boundaries. go-plus.json TAD|topologically associated domain http://purl.obolibrary.org/obo/SO_0002304 GO:0070244 biolink:BiologicalProcess negative regulation of thymocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process. go-plus.json down-regulation of thymocyte apoptosis|inhibition of thymocyte apoptosis|negative regulation of thymocyte apoptosis|negative regulation of immature T cell apoptosis|down regulation of thymocyte apoptosis|downregulation of thymocyte apoptosis http://purl.obolibrary.org/obo/GO_0070244 GO:0070245 biolink:BiologicalProcess positive regulation of thymocyte apoptotic process Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process. go-plus.json positive regulation of thymocyte apoptosis|up-regulation of thymocyte apoptosis|positive regulation of immature T cell apoptosis|upregulation of thymocyte apoptosis|up regulation of thymocyte apoptosis|activation of thymocyte apoptosis|stimulation of thymocyte apoptosis http://purl.obolibrary.org/obo/GO_0070245 SO:0002305 biolink:SequenceFeature topologically_associated_domain_boundary A DNA region enriched in DNA loop anchors and across which DNA loops occur less often than expected by chance. go-plus.json TAD boundary|TAD_boundary|topologically associated domain boundary http://purl.obolibrary.org/obo/SO_0002305 UBERON:0003587 biolink:AnatomicalEntity limb connective tissue A portion of connective tissue that is part of a limb [Automatically generated definition]. go-plus.json portion of connective tissue of limb|textus connectivus of limb|limb portion of connective tissue|connective tissue of limb|limb textus connectivus http://purl.obolibrary.org/obo/UBERON_0003587 GO:0070242 biolink:BiologicalProcess thymocyte apoptotic process Any apoptotic process in a thymocyte, an immature T cell located in the thymus. go-plus.json thymocyte apoptosis|immature T cell apoptosis http://purl.obolibrary.org/obo/GO_0070242 UBERON:0003584 biolink:AnatomicalEntity mammary gland connective tissue The fibrous supportive tissue of the mammary gland. go-plus.json lactiferous gland connective tissue|connective tissue of mammary gland|lactiferous gland stroma|mammary stroma|connective tissue of lobe of breast|lactiferous gland portion of connective tissue|connective tissue of lobe of mammary gland|stroma of lactiferous gland|connective tissue of lactiferous gland|mammary gland stroma http://purl.obolibrary.org/obo/UBERON_0003584 GO:0070243 biolink:BiologicalProcess regulation of thymocyte apoptotic process Any process that modulates the occurrence or rate of thymocyte death by apoptotic process. go-plus.json regulation of immature T cell apoptosis|regulation of thymocyte apoptosis http://purl.obolibrary.org/obo/GO_0070243 UBERON:0003585 biolink:AnatomicalEntity dermis connective tissue A portion of connective tissue that is part of a dermis [Automatically generated definition]. go-plus.json connective tissue of dermis|dermis portion of connective tissue|dermis textus connectivus|portion of connective tissue of dermis|textus connectivus of dermis http://purl.obolibrary.org/obo/UBERON_0003585 UBERON:0003609 biolink:AnatomicalEntity aorta elastic tissue The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall. go-plus.json elastic tissue of trunk of aortic tree|textus connectivus elasticus of adult aorta|elastic connective tissue of trunk of aortic tree|dorsal aorta textus connectivus elasticus|dorsal aorta elastic tissue|adult aorta textus connectivus elasticus|aorta elastic laminae|adult aorta elastic tissue|textus connectivus elasticus of dorsal aorta|trunk of aortic tree elastic connective tissue|aorta textus connectivus elasticus|elastic tissue of dorsal aorta|aorta elastic lamina|aorta elastic connective tissue|elastic connective tissue of dorsal aorta|elastic connective tissue of aorta|trunk of aortic tree textus connectivus elasticus|trunk of aortic tree elastic tissue|elastic tissue of aorta|adult aorta elastic connective tissue|elastic connective tissue of adult aorta|textus connectivus elasticus of aorta|dorsal aorta elastic connective tissue|textus connectivus elasticus of trunk of aortic tree|elastic tissue of adult aorta http://purl.obolibrary.org/obo/UBERON_0003609 CHEBI:71476 biolink:ChemicalSubstance EC 2.3.1.85 (fatty acid synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_71476 UBERON:0003607 biolink:AnatomicalEntity forelimb long bone A long bone that is part of a forelimb [Automatically generated definition]. go-plus.json long bone of upper extremity|long bone of anteriormost limb|long bone of fore limb|upper extremity long bone|long bone of forelimb|anteriormost limb long bone|fore limb long bone|long bone of superior member|wing long bone|superior member long bone http://purl.obolibrary.org/obo/UBERON_0003607 CHEBI:71477 biolink:ChemicalSubstance guanosine 3'-diphosphate 5'-triphosphate(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71477 SO:0002221 biolink:SequenceFeature eukaryotic_promoter A regulatory_region including the Transcription Start Site (TSS) of a gene and serving as a platform for Pre-Initiation Complex (PIC) assembly, enabling transcription of a gene under certain conditions. go-plus.json Eukaryotic promoter http://purl.obolibrary.org/obo/SO_0002221 UBERON:0003608 biolink:AnatomicalEntity hindlimb long bone A long bone that is part of a hindlimb [Automatically generated definition]. go-plus.json long bone of inferior member|long bone of hind limb|long bone of lower extremity|inferior member long bone|hind limb long bone|lower extremity long bone|long bone of hindlimb http://purl.obolibrary.org/obo/UBERON_0003608 SO:0002222 biolink:SequenceFeature prokaryotic_promoter A regulatory_region essential for the specific initiation of transcription at a defined location in a DNA molecule, although this location might not be one single base. It is recognized by a specific RNA polymerase(RNAP)-holoenzyme, and this recognition is not necessarily autonomous. go-plus.json Prokaryotic promoter http://purl.obolibrary.org/obo/SO_0002222 UBERON:0003605 biolink:AnatomicalEntity eye skin gland A skin gland that is part of a camera-type eye [Automatically generated definition]. go-plus.json skin glands set of vertebrate eye|skin glands of vertebrate eye|skin glands of camera-type eye|vertebrate eye skin glands set|skin glands set of camera-type eye|vertebrate eye skin glands|camera-type eye skin gland|skin gland of camera-type eye|camera-type eye skin glands set|camera-type eye skin glands|skin gland of vertebrate eye|vertebrate eye skin gland http://purl.obolibrary.org/obo/UBERON_0003605 UBERON:0003606 biolink:AnatomicalEntity limb long bone A long bone that is part of a limb [Automatically generated definition]. go-plus.json long bone of limb http://purl.obolibrary.org/obo/UBERON_0003606 UBERON:0003603 biolink:AnatomicalEntity lower respiratory tract cartilage A cartilage that is part of a lower respiratory tract [Automatically generated definition]. go-plus.json cartilage of lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0003603 UBERON:0003604 biolink:AnatomicalEntity trachea cartilage the ring-shaped cartilaginous structures that support the trachea go-plus.json cartilago trachealis|cartilage of the trachea|cartilaginous ring of trachea|trachea ring|tracheal cartilage|tracheal ring|cartilaginous trachea cartilage|cartilage of trachea|cartilage of windpipe|ring of the trachea|cartilagines tracheales|windpipe cartilage http://purl.obolibrary.org/obo/UBERON_0003604 UBERON:0003613 biolink:AnatomicalEntity cardiovascular system elastic tissue An elastic tissue that is part of a circulatory system [Automatically generated definition]. go-plus.json textus connectivus elasticus of cardiovascular system|circulatory system textus connectivus elasticus|textus connectivus elasticus of circulatory system|circulatory system elastic tissue|elastic tissue of circulatory system|elastic connective tissue of circulatory system|circulatory system elastic connective tissue|cardiovascular system elastic connective tissue|elastic connective tissue of cardiovascular system|elastic tissue of cardiovascular system|cardiovascular system textus connectivus elasticus http://purl.obolibrary.org/obo/UBERON_0003613 UBERON:0003610 biolink:AnatomicalEntity heart elastic tissue The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers. go-plus.json cardiac elastic tissue|heart elastic connective tissue|elastic connective tissue of heart|heart textus connectivus elasticus|elastic tissue of heart|textus connectivus elasticus of heart http://purl.obolibrary.org/obo/UBERON_0003610 UBERON:0003611 biolink:AnatomicalEntity respiratory system elastic tissue An elastic tissue that is part of a respiratory system [Automatically generated definition]. go-plus.json elastic connective tissue of respiratory system|apparatus respiratorius textus connectivus elasticus|apparatus respiratorius elastic tissue|respiratory system elastic connective tissue|respiratory system textus connectivus elasticus|apparatus respiratorius elastic connective tissue|elastic connective tissue of apparatus respiratorius|elastic tissue of apparatus respiratorius|textus connectivus elasticus of respiratory system|textus connectivus elasticus of apparatus respiratorius|elastic tissue of respiratory system http://purl.obolibrary.org/obo/UBERON_0003611 CHEBI:71487 biolink:ChemicalSubstance chanoclavine-I aldehyde(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71487 chebi_ph7_3 CHEBI:71488 biolink:ChemicalSubstance all-cis-8,11,14,17-icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71488 CHEBI:71489 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71489 chebi_ph7_3 GO:0045402 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045402 GO:0045403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045403 GO:0045400 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045400 GO:0045401 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045401 PR:000007141 biolink:Protein erythropoietin A protein that is a translation product of the human EPO gene or a 1:1 ortholog thereof. go-plus.json EPO|epoetin http://purl.obolibrary.org/obo/PR_000007141 PR:000007142 biolink:Protein erythropoietin receptor A protein that is a translation product of the human EPOR gene or a 1:1 ortholog thereof. go-plus.json EPOR|EPO-R http://purl.obolibrary.org/obo/PR_000007142 NCBITaxon:721805 biolink:OrganismalEntity Amygdaleae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_721805 GO:0045408 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045408 GO:0045409 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045409 GO:0045406 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045406 GO:0045407 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045407 GO:0045404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045404 GO:0045405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045405 UBERON:0003601 biolink:AnatomicalEntity neck cartilage A cartilage that is part of a neck [Automatically generated definition]. go-plus.json neck (volume) cartilage|cartilage of neck|cartilage of neck (volume) http://purl.obolibrary.org/obo/UBERON_0003601 CHEBI:71481 biolink:ChemicalSubstance (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71481 chebi_ph7_3 PO:0007033 biolink:OntologyClass whole plant development stage A plant structure development stage (PO:0009012) that has as primary participant a whole plant (PO:0000003). go-plus.json cereal plant growth stage ontology (GRO:0007199) (related)|sorghum growth stage (GRO:0007124) (related)|rice growth stage (GRO:0007040) (related)|maize growth stage (GRO:0007002) (related)|wheat, barley and oat growth stage (GRO:0007156) (related)|plant growth stages in Arabidopsis (TAIR:0000021) (related)|Solanaceae whole plant growth stages (SGN:0000001) (related) http://purl.obolibrary.org/obo/PO_0007033 GO:1901905 biolink:BiologicalProcess response to tamsulosin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1901905 GO:1901906 biolink:BiologicalProcess diadenosine pentaphosphate metabolic process The chemical reactions and pathways involving diadenosine pentaphosphate. go-plus.json diadenosine pentaphosphate metabolism|diadenosyl pentaphosphate metabolism|diadenosyl pentaphosphate metabolic process http://purl.obolibrary.org/obo/GO_1901906 CHEBI:71498 biolink:ChemicalSubstance 1-O-(4-coumaroyl)-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_71498 chebi_ph7_3 GO:1901903 biolink:BiologicalProcess tyrocidine catabolic process The chemical reactions and pathways resulting in the breakdown of tyrocidine. go-plus.json tyrocidine breakdown|tyrocidine catabolism|tyrocidine degradation http://purl.obolibrary.org/obo/GO_1901903 CHEBI:71499 biolink:ChemicalSubstance cyanidin 3-O-{6-O-[6-O-(4-coumaroyl)-beta-D-glucosyl]-2-O-beta-D-xylosyl-beta-D-galactoside} go-plus.json http://purl.obolibrary.org/obo/CHEBI_71499 GO:1901904 biolink:BiologicalProcess tyrocidine biosynthetic process The chemical reactions and pathways resulting in the formation of tyrocidine. go-plus.json tyrocidine biosynthesis|tyrocidine anabolism|tyrocidine synthesis|tyrocidine formation http://purl.obolibrary.org/obo/GO_1901904 GO:1901901 biolink:BiologicalProcess regulation of protein localization to cell division site involved in cytokinesis Any regulation of protein localization to cell division site that is involved in cytokinesis. go-plus.json regulation of protein localisation to cell division site involved in cytokinesis http://purl.obolibrary.org/obo/GO_1901901 GO:1901902 biolink:BiologicalProcess tyrocidine metabolic process The chemical reactions and pathways involving tyrocidine. go-plus.json tyrocidine metabolism http://purl.obolibrary.org/obo/GO_1901902 GO:1901900 biolink:BiologicalProcess regulation of protein localization to cell division site Any process that modulates the frequency, rate or extent of protein localization to cell division site. go-plus.json regulation of protein localisation to cell division site http://purl.obolibrary.org/obo/GO_1901900 GO:0045413 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045413 GO:0045414 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045414 GO:0045411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045411 GO:0045412 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045412 GO:0045410 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045410 GO:0045419 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045419 CHEBI:141748 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141748 chebi_ph7_3 GO:0045417 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045417 GO:0045418 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045418 CHEBI:141743 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141743 chebi_ph7_3 GO:0045415 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045415 GO:0045416 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045416 CHEBI:71490 biolink:ChemicalSubstance precorrin-7(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71490 chebi_ph7_3 CHEBI:71491 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71491 chebi_ph7_3 CHEBI:71492 biolink:ChemicalSubstance (2R)-3-(3,4-dihydroxyphenyl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71492 chebi_ph7_3 GO:1901909 biolink:BiologicalProcess diadenosine hexaphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate. go-plus.json diadenosine hexaphosphate catabolism|diadenosyl hexaphosphate degradation|diadenosyl hexaphosphate breakdown|diadenosyl hexaphosphate catabolic process|diadenosyl hexaphosphate catabolism http://purl.obolibrary.org/obo/GO_1901909 CHEBI:71493 biolink:ChemicalSubstance (R)-rosmarinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71493 chebi_ph7_3 CHEBI:71494 biolink:ChemicalSubstance cis-trans-nepetalactol go-plus.json http://purl.obolibrary.org/obo/CHEBI_71494 chebi_ph7_3 GO:1901907 biolink:BiologicalProcess diadenosine pentaphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate. go-plus.json diadenosine pentaphosphate catabolism|diadenosyl pentaphosphate catabolism|diadenosyl pentaphosphate degradation|diadenosyl pentaphosphate breakdown|diadenosyl pentaphosphate catabolic process http://purl.obolibrary.org/obo/GO_1901907 GO:1901908 biolink:BiologicalProcess diadenosine hexaphosphate metabolic process The chemical reactions and pathways involving diadenosine hexaphosphate. go-plus.json diadenosyl hexaphosphate metabolism|diadenosine hexaphosphate metabolism|diadenosyl hexaphosphate metabolic process http://purl.obolibrary.org/obo/GO_1901908 GO:1901916 biolink:MolecularActivity obsolete protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis OBSOLETE. Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis. go-plus.json protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis http://purl.obolibrary.org/obo/GO_1901916 SO:0002234 biolink:SequenceFeature pumilio_response_element A cis-acting element involved in RNA stability found in the 3' UTR of some RNA (consensus UGUAAAUA). go-plus.json pumilio response element|PRE binding RNA http://purl.obolibrary.org/obo/SO_0002234 GO:1901917 biolink:BiologicalProcess regulation of exoribonuclease activity Any process that modulates the frequency, rate or extent of exoribonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_1901917 GO:1901914 biolink:BiologicalProcess negative regulation of capsule organization Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization. go-plus.json down regulation of capsule organization|inhibition of capsule organization|inhibition of capsule organization and biogenesis|down regulation of capsule organization and biogenesis|down-regulation of capsule organisation|negative regulation of capsule organisation|downregulation of capsule organization and biogenesis|down-regulation of capsule organization|downregulation of capsule organisation|negative regulation of capsule organization and biogenesis|down-regulation of capsule organization and biogenesis|down regulation of capsule organisation|inhibition of capsule organisation|downregulation of capsule organization http://purl.obolibrary.org/obo/GO_1901914 GO:1901915 biolink:BiologicalProcess positive regulation of capsule organization Any process that activates or increases the frequency, rate or extent of capsule organization. go-plus.json upregulation of capsule organization|up-regulation of capsule organisation|activation of capsule organisation|upregulation of capsule organization and biogenesis|up-regulation of capsule organization|activation of capsule organization|positive regulation of capsule organisation|up regulation of capsule organization and biogenesis|up regulation of capsule organisation|positive regulation of capsule organization and biogenesis|activation of capsule organization and biogenesis|up regulation of capsule organization|upregulation of capsule organisation|up-regulation of capsule organization and biogenesis http://purl.obolibrary.org/obo/GO_1901915 GO:1901912 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1901912 GO:1901913 biolink:BiologicalProcess regulation of capsule organization Any process that modulates the frequency, rate or extent of capsule organization. go-plus.json regulation of capsule organization and biogenesis|regulation of capsule organisation http://purl.obolibrary.org/obo/GO_1901913 GO:1901910 biolink:BiologicalProcess adenosine 5'-(hexahydrogen pentaphosphate) metabolic process The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate). go-plus.json adenosine 5'-(hexahydrogen pentaphosphate) metabolism http://purl.obolibrary.org/obo/GO_1901910 GO:1901911 biolink:BiologicalProcess adenosine 5'-(hexahydrogen pentaphosphate) catabolic process The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate). go-plus.json adenosine 5'-(hexahydrogen pentaphosphate) breakdown|adenosine 5'-(hexahydrogen pentaphosphate) catabolism|adenosine 5'-(hexahydrogen pentaphosphate) degradation http://purl.obolibrary.org/obo/GO_1901911 GO:0045424 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045424 GO:0045425 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045425 GO:0045422 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045422 GO:0045423 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045423 GO:0045420 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045420 GO:0045421 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045421 GO:0045428 biolink:BiologicalProcess regulation of nitric oxide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. go-plus.json regulation of nitric oxide synthesis|regulation of nitric oxide formation|regulation of nitric oxide biosynthesis|regulation of nitric oxide anabolism http://purl.obolibrary.org/obo/GO_0045428 GO:0045429 biolink:BiologicalProcess positive regulation of nitric oxide biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. go-plus.json stimulation of nitric oxide biosynthetic process|up-regulation of nitric oxide biosynthetic process|upregulation of nitric oxide biosynthetic process|positive regulation of nitric oxide anabolism|positive regulation of nitric oxide synthesis|up regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide formation|activation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthesis http://purl.obolibrary.org/obo/GO_0045429 GO:0045426 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045426 GO:0045427 biolink:BiologicalProcess obsolete enzyme active site formation via (phospho-5'-guanosine)-L-histidine OBSOLETE. The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine. go-plus.json http://purl.obolibrary.org/obo/GO_0045427 GO:1901918 biolink:BiologicalProcess negative regulation of exoribonuclease activity Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity. go-plus.json down-regulation of exoribonuclease activity|downregulation of exoribonuclease activity|down regulation of exoribonuclease activity|inhibition of exoribonuclease activity http://purl.obolibrary.org/obo/GO_1901918 GO:1901919 biolink:BiologicalProcess positive regulation of exoribonuclease activity Any process that activates or increases the frequency, rate or extent of exoribonuclease activity. go-plus.json up-regulation of exoribonuclease activity|activation of exoribonuclease activity|up regulation of exoribonuclease activity|upregulation of exoribonuclease activity http://purl.obolibrary.org/obo/GO_1901919 GO:1901927 biolink:BiologicalProcess cadinene catabolic process The chemical reactions and pathways resulting in the breakdown of cadinene. go-plus.json cadinene catabolism|cadinene degradation|cadinene breakdown http://purl.obolibrary.org/obo/GO_1901927 GO:1901928 biolink:BiologicalProcess cadinene biosynthetic process The chemical reactions and pathways resulting in the formation of cadinene. go-plus.json cadinene synthesis|cadinene formation|cadinene biosynthesis|cadinene anabolism http://purl.obolibrary.org/obo/GO_1901928 GO:1901925 biolink:BiologicalProcess negative regulation of protein import into nucleus during spindle assembly checkpoint Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p). go-plus.json Kap121p transport inhibitory pathway|KTIP|negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_1901925 GO:1901926 biolink:BiologicalProcess cadinene metabolic process The chemical reactions and pathways involving cadinene. go-plus.json cadinene metabolism http://purl.obolibrary.org/obo/GO_1901926 GO:1901923 biolink:BiologicalProcess negative regulation of sclerotium development Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development. go-plus.json downregulation of sclerotium development|down regulation of sclerotium development|inhibition of sclerotium development|down-regulation of sclerotium development http://purl.obolibrary.org/obo/GO_1901923 GO:1901924 biolink:BiologicalProcess positive regulation of sclerotium development Any process that activates or increases the frequency, rate or extent of sclerotium development. go-plus.json up regulation of sclerotium development|upregulation of sclerotium development|up-regulation of sclerotium development|activation of sclerotium development http://purl.obolibrary.org/obo/GO_1901924 GO:1901921 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex Any phosphorylation of RNA polymerase II C-terminal domain that is involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex. go-plus.json CTD domain phosphorylation of RNA polymerase II involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex http://purl.obolibrary.org/obo/GO_1901921 GO:1901922 biolink:BiologicalProcess regulation of sclerotium development Any process that modulates the frequency, rate or extent of sclerotium development. go-plus.json http://purl.obolibrary.org/obo/GO_1901922 GO:0045435 biolink:MolecularActivity lycopene epsilon cyclase activity Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene). go-plus.json lycopene cyclase http://purl.obolibrary.org/obo/GO_0045435 GO:0045436 biolink:MolecularActivity lycopene beta cyclase activity Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively. RHEA:32219|MetaCyc:RXN1F-150 go-plus.json crtL|lycopene cyclase http://purl.obolibrary.org/obo/GO_0045436 GO:1901920 biolink:BiologicalProcess peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity. go-plus.json peptidyl-tyrosine dephosphorylation involved in protein kinase activation http://purl.obolibrary.org/obo/GO_1901920 GO:0045433 biolink:BiologicalProcess male courtship behavior, veined wing generated song production The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song. go-plus.json male courtship behavior, song production|male courtship behaviour, veined wing generated song production|male courtship behaviour, song production http://purl.obolibrary.org/obo/GO_0045433 GO:0045434 biolink:BiologicalProcess negative regulation of female receptivity, post-mating Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating. go-plus.json down-regulation of female receptivity, post-mating|inhibition of female receptivity, post-mating|down regulation of female receptivity, post-mating|downregulation of female receptivity, post-mating http://purl.obolibrary.org/obo/GO_0045434 CHEBI:46470 biolink:ChemicalSubstance uridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_46470 GO:0045431 biolink:MolecularActivity flavonol synthase activity Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O. EC:1.14.20.6|RHEA:21088 go-plus.json flavonoid 2-oxoglutarate-dependent dioxygenase activity|FLS activity|dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0045431 GO:0045432 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045432 GO:0045430 biolink:MolecularActivity chalcone isomerase activity Catalysis of the reaction: a chalcone = a flavanone. MetaCyc:CHALCONE-ISOMERASE-RXN|EC:5.5.1.6 go-plus.json flavanone lyase (decyclizing)|chalcone--flavonone isomerase activity|chalcone-flavanone isomerase activity http://purl.obolibrary.org/obo/GO_0045430 GO:0045439 biolink:MolecularActivity isopenicillin-N epimerase activity Catalysis of the reaction: isopenicillin N = penicillin N. RHEA:20033|KEGG_REACTION:R04147|MetaCyc:5.1.1.17-RXN|EC:5.1.1.17 go-plus.json isopenicillin N epimerase activity|penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity http://purl.obolibrary.org/obo/GO_0045439 CHEBI:141724 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141724 chebi_ph7_3 GO:0045437 biolink:MolecularActivity uridine nucleosidase activity Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil. RHEA:15577|EC:3.2.2.3|KEGG_REACTION:R01080|MetaCyc:URIDINE-NUCLEOSIDASE-RXN go-plus.json uridine ribohydrolase activity|uridine hydrolase activity http://purl.obolibrary.org/obo/GO_0045437 GO:0045438 biolink:MolecularActivity delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol. go-plus.json ACV synthetase activity http://purl.obolibrary.org/obo/GO_0045438 UBERON:0003656 biolink:AnatomicalEntity mesopodium bone A bone that is part of a mesopodial skeleton. go-plus.json basipodium bone|mesopod bone|carpal/tarsal bone|mesopodial bone http://purl.obolibrary.org/obo/UBERON_0003656 UBERON:0003657 biolink:AnatomicalEntity limb joint Any joint that is part of a (free) limb. go-plus.json joint of limb|skeletal limb joint|joint of limb skeletal system http://purl.obolibrary.org/obo/UBERON_0003657 GO:1901929 biolink:BiologicalProcess alpha-copaene metabolic process The chemical reactions and pathways involving alpha-copaene. go-plus.json alpha-copaene metabolism http://purl.obolibrary.org/obo/GO_1901929 GO:1901938 biolink:BiologicalProcess (-)-exo-alpha-bergamotene metabolic process The chemical reactions and pathways involving (-)-exo-alpha-bergamotene. go-plus.json (-)-exo-alpha-bergamotene metabolism http://purl.obolibrary.org/obo/GO_1901938 GO:1901939 biolink:BiologicalProcess (-)-exo-alpha-bergamotene catabolic process The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene. go-plus.json (-)-exo-alpha-bergamotene degradation|(-)-exo-alpha-bergamotene breakdown|(-)-exo-alpha-bergamotene catabolism http://purl.obolibrary.org/obo/GO_1901939 GO:1901936 biolink:BiologicalProcess beta-caryophyllene catabolic process The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene. go-plus.json beta-caryophyllene degradation|beta-caryophyllene breakdown|beta-caryophyllene catabolism http://purl.obolibrary.org/obo/GO_1901936 GO:1901937 biolink:BiologicalProcess beta-caryophyllene biosynthetic process The chemical reactions and pathways resulting in the formation of beta-caryophyllene. go-plus.json beta-caryophyllene biosynthesis|beta-caryophyllene anabolism|beta-caryophyllene synthesis|beta-caryophyllene formation http://purl.obolibrary.org/obo/GO_1901937 GO:1901934 biolink:BiologicalProcess bicyclogermacrene biosynthetic process The chemical reactions and pathways resulting in the formation of bicyclogermacrene. go-plus.json bicyclogermacrene anabolism|bicyclogermacrene synthesis|bicyclogermacrene formation|bicyclogermacrene biosynthesis http://purl.obolibrary.org/obo/GO_1901934 GO:1901935 biolink:BiologicalProcess beta-caryophyllene metabolic process The chemical reactions and pathways involving beta-caryophyllene. go-plus.json beta-caryophyllene metabolism http://purl.obolibrary.org/obo/GO_1901935 GO:1901932 biolink:BiologicalProcess bicyclogermacrene metabolic process The chemical reactions and pathways involving bicyclogermacrene. go-plus.json bicyclogermacrene metabolism http://purl.obolibrary.org/obo/GO_1901932 GO:1901933 biolink:BiologicalProcess bicyclogermacrene catabolic process The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene. go-plus.json bicyclogermacrene degradation|bicyclogermacrene breakdown|bicyclogermacrene catabolism http://purl.obolibrary.org/obo/GO_1901933 GO:1901930 biolink:BiologicalProcess alpha-copaene catabolic process The chemical reactions and pathways resulting in the breakdown of alpha-copaene. go-plus.json alpha-copaene breakdown|alpha-copaene catabolism|alpha-copaene degradation http://purl.obolibrary.org/obo/GO_1901930 GO:0045446 biolink:BiologicalProcess endothelial cell differentiation The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0045446 GO:0045447 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045447 GO:1901931 biolink:BiologicalProcess alpha-copaene biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-copaene. go-plus.json alpha-copaene anabolism|alpha-copaene synthesis|alpha-copaene formation|alpha-copaene biosynthesis http://purl.obolibrary.org/obo/GO_1901931 GO:0045444 biolink:BiologicalProcess fat cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. go-plus.json adipocyte differentiation|adipose cell differentiation|adipogenesis|adipocyte cell differentiation http://purl.obolibrary.org/obo/GO_0045444 GO:0045445 biolink:BiologicalProcess myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. go-plus.json myoblast cell differentiation http://purl.obolibrary.org/obo/GO_0045445 GO:0045442 biolink:MolecularActivity deacetoxycephalosporin-C hydroxylase activity Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate. MetaCyc:1.14.11.26-RXN|RHEA:16805|KEGG_REACTION:R05229|EC:1.14.11.26 go-plus.json deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|DAOC hydroxylase activity|deacetylcephalosporin C synthase activity|deacetoxycephalosporin C hydroxylase activity|3'-methylcephem hydroxylase activity|beta-lactam hydroxylase activity|DACS http://purl.obolibrary.org/obo/GO_0045442 GO:0045443 biolink:BiologicalProcess juvenile hormone secretion The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0045443 GO:0045440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045440 GO:0045441 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045441 GO:0045448 biolink:BiologicalProcess mitotic cell cycle, embryonic The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0045448 CHEBI:141711 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141711 chebi_ph7_3 GO:0045449 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045449 UBERON:0003643 biolink:AnatomicalEntity respiratory system arterial blood vessel An arterial blood vessel that is part of a respiratory system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003643 NCBITaxon:452284 biolink:OrganismalEntity Ustilaginomycotina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_452284 UBERON:0003644 biolink:AnatomicalEntity kidney arterial blood vessel An arterial blood vessel that is part of a kidney [Automatically generated definition]. go-plus.json kidney arterial system http://purl.obolibrary.org/obo/UBERON_0003644 SO:0002247 biolink:SequenceFeature sncRNA A non-coding RNA less than 200 nucleotides in length. go-plus.json Small noncoding RNA http://purl.obolibrary.org/obo/SO_0002247 GO:1901949 biolink:BiologicalProcess 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate. go-plus.json 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate formation|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthesis|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate anabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate synthesis http://purl.obolibrary.org/obo/GO_1901949 GO:0045450 biolink:BiologicalProcess bicoid mRNA localization Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis. go-plus.json establishment and maintenance of bicoid mRNA localization|bicoid mRNA localisation http://purl.obolibrary.org/obo/GO_0045450 CHEBI:22487 biolink:ChemicalSubstance alpha-aminoacyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22487 GO:1901947 biolink:BiologicalProcess 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate. go-plus.json 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolism http://purl.obolibrary.org/obo/GO_1901947 CHEBI:22484 biolink:ChemicalSubstance galactosamine oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22484 CHEBI:22485 biolink:ChemicalSubstance glucosamine oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22485 GO:1901948 biolink:BiologicalProcess 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate. go-plus.json 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate degradation|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate breakdown http://purl.obolibrary.org/obo/GO_1901948 GO:1901945 biolink:BiologicalProcess miltiradiene catabolic process The chemical reactions and pathways resulting in the breakdown of miltiradiene. go-plus.json miltiradiene catabolism|miltiradiene degradation|miltiradiene breakdown http://purl.obolibrary.org/obo/GO_1901945 GO:1901946 biolink:BiologicalProcess miltiradiene biosynthetic process The chemical reactions and pathways resulting in the formation of miltiradiene. go-plus.json miltiradiene anabolism|miltiradiene synthesis|miltiradiene formation|miltiradiene biosynthesis http://purl.obolibrary.org/obo/GO_1901946 GO:1901943 biolink:BiologicalProcess (+)-epi-alpha-bisabolol biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol. go-plus.json (+)-epi-alpha-bisabolol anabolism|(+)-epi-alpha-bisabolol synthesis|(+)-epi-alpha-bisabolol formation|(+)-epi-alpha-bisabolol biosynthesis http://purl.obolibrary.org/obo/GO_1901943 GO:1901944 biolink:BiologicalProcess miltiradiene metabolic process The chemical reactions and pathways involving miltiradiene. go-plus.json miltiradiene metabolism http://purl.obolibrary.org/obo/GO_1901944 GO:1901941 biolink:BiologicalProcess (+)-epi-alpha-bisabolol metabolic process The chemical reactions and pathways involving (+)-epi-alpha-bisabolol. go-plus.json (+)-epi-alpha-bisabolol metabolism http://purl.obolibrary.org/obo/GO_1901941 GO:0045457 biolink:BiologicalProcess ecdysteroid secretion The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. go-plus.json http://purl.obolibrary.org/obo/GO_0045457 GO:1901942 biolink:BiologicalProcess (+)-epi-alpha-bisabolol catabolic process The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol. go-plus.json (+)-epi-alpha-bisabolol catabolism|(+)-epi-alpha-bisabolol degradation|(+)-epi-alpha-bisabolol breakdown http://purl.obolibrary.org/obo/GO_1901942 GO:0045458 biolink:BiologicalProcess recombination within rDNA repeats Genetic recombination within the DNA of the genes coding for ribosomal RNA. go-plus.json recombination within ribosomal DNA repeats http://purl.obolibrary.org/obo/GO_0045458 GO:0045455 biolink:BiologicalProcess ecdysteroid metabolic process The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females. go-plus.json ecdysteroid metabolism http://purl.obolibrary.org/obo/GO_0045455 GO:1901940 biolink:BiologicalProcess (-)-exo-alpha-bergamotene biosynthetic process The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene. go-plus.json (-)-exo-alpha-bergamotene synthesis|(-)-exo-alpha-bergamotene formation|(-)-exo-alpha-bergamotene anabolism|(-)-exo-alpha-bergamotene biosynthesis http://purl.obolibrary.org/obo/GO_1901940 GO:0045456 biolink:BiologicalProcess ecdysteroid biosynthetic process The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. go-plus.json ecdysteroid biosynthesis|ecdysteroid anabolism|ecdysteroid synthesis|ecdysteroid formation http://purl.obolibrary.org/obo/GO_0045456 GO:0045453 biolink:BiologicalProcess bone resorption The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. Wikipedia:Bone_resorption go-plus.json http://purl.obolibrary.org/obo/GO_0045453 GO:0045454 biolink:BiologicalProcess cell redox homeostasis Any process that maintains the redox environment of a cell or compartment within a cell. Wikipedia:Redox go-plus.json regulation of cell redox homeostasis|regulation of redox homeostasis http://purl.obolibrary.org/obo/GO_0045454 goslim_drosophila|goslim_metagenomics CHEBI:22483 biolink:ChemicalSubstance amino oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22483 GO:0045451 biolink:BiologicalProcess pole plasm oskar mRNA localization Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. go-plus.json establishment and maintenance of oskar mRNA localization in pole plasm|establishment and maintenance of pole plasm oskar mRNA localization|pole plasm oskar mRNA localisation|oocyte pole plasm oskar mRNA localization http://purl.obolibrary.org/obo/GO_0045451 CHEBI:22480 biolink:ChemicalSubstance amino disaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22480 GO:0045452 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045452 GO:0070419 biolink:CellularComponent nonhomologous end joining complex A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends. go-plus.json non-homologous end joining complex|NHEJ complex http://purl.obolibrary.org/obo/GO_0070419 GO:0070417 biolink:BiologicalProcess cellular response to cold Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. go-plus.json cellular response to cold stress http://purl.obolibrary.org/obo/GO_0070417 GO:0070418 biolink:CellularComponent DNA-dependent protein kinase complex A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku. go-plus.json DNA-dependent protein kinase, DNA-end-binding complex|DNA-PK complex|DNA-PK-Ku antigen complex http://purl.obolibrary.org/obo/GO_0070418 GO:0045459 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide. RESID:AA0326 go-plus.json iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl triiron tetrasulphide http://purl.obolibrary.org/obo/GO_0045459 GO:0070415 biolink:BiologicalProcess trehalose metabolism in response to cold stress The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. go-plus.json trehalose metabolic process involved in response to cold stress http://purl.obolibrary.org/obo/GO_0070415 GO:0070416 biolink:BiologicalProcess trehalose metabolism in response to water deprivation The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water. go-plus.json trehalose metabolic process involved in response to water deprivation http://purl.obolibrary.org/obo/GO_0070416 GO:0070413 biolink:BiologicalProcess trehalose metabolism in response to stress The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress. go-plus.json trehalose metabolic process involved in response to stress http://purl.obolibrary.org/obo/GO_0070413 GO:0070414 biolink:BiologicalProcess trehalose metabolism in response to heat stress The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. go-plus.json trehalose metabolic process involved in response to heat stress http://purl.obolibrary.org/obo/GO_0070414 GO:0070411 biolink:MolecularActivity I-SMAD binding Binding to an inhibitory SMAD signaling protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070411 GO:0070412 biolink:MolecularActivity R-SMAD binding Binding to a receptor-regulated SMAD signaling protein. go-plus.json receptor-regulated SMAD binding|pathway restricted SMAD binding|receptor regulated SMAD binding|pathway-restricted SMAD binding http://purl.obolibrary.org/obo/GO_0070412 GO:0070410 biolink:MolecularActivity co-SMAD binding Binding to a common mediator SMAD signaling protein. go-plus.json common partner SMAD binding|common-mediator SMAD binding|common-partner SMAD binding|common mediator SMAD binding http://purl.obolibrary.org/obo/GO_0070410 GO:0045460 biolink:BiologicalProcess sterigmatocystin metabolic process The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. go-plus.json sterigmatocystin metabolism http://purl.obolibrary.org/obo/GO_0045460 CHEBI:22497 biolink:ChemicalSubstance aminobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_22497 CHEBI:46442 biolink:ChemicalSubstance vanadate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46442 GO:0045461 biolink:BiologicalProcess sterigmatocystin biosynthetic process The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. go-plus.json sterigmatocystin anabolism|sterigmatocystin synthesis|sterigmatocystin formation|sterigmatocystin biosynthesis http://purl.obolibrary.org/obo/GO_0045461 UBERON:0003618 biolink:AnatomicalEntity aorta tunica media The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers. go-plus.json tunica media of trunk of aortic tree|dorsal aorta tunica media|adult aorta tunica media|tunica media of dorsal aorta|tunica media of aorta|trunk of aortic tree tunica media|tunica media of adult aorta http://purl.obolibrary.org/obo/UBERON_0003618 GO:1901958 biolink:BiologicalProcess negative regulation of cutin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process. go-plus.json inhibition of cutin synthesis|inhibition of cutin biosynthesis|inhibition of cutin formation|down regulation of cutin anabolism|down regulation of cutin synthesis|downregulation of cutin anabolism|down regulation of cutin formation|downregulation of cutin synthesis|down-regulation of cutin biosynthesis|negative regulation of cutin biosynthesis|down-regulation of cutin biosynthetic process|downregulation of cutin formation|negative regulation of cutin anabolism|down-regulation of cutin anabolism|negative regulation of cutin synthesis|down-regulation of cutin synthesis|downregulation of cutin biosynthetic process|negative regulation of cutin formation|down-regulation of cutin formation|downregulation of cutin biosynthesis|down regulation of cutin biosynthesis|down regulation of cutin biosynthetic process|inhibition of cutin anabolism|inhibition of cutin biosynthetic process http://purl.obolibrary.org/obo/GO_1901958 CHEBI:22495 biolink:ChemicalSubstance aminobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22495 GO:1901959 biolink:BiologicalProcess positive regulation of cutin biosynthetic process Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process. go-plus.json upregulation of cutin biosynthesis|upregulation of cutin biosynthetic process|up-regulation of cutin formation|upregulation of cutin anabolism|upregulation of cutin synthesis|up-regulation of cutin biosynthesis|upregulation of cutin formation|up-regulation of cutin biosynthetic process|activation of cutin biosynthetic process|up regulation of cutin anabolism|positive regulation of cutin anabolism|activation of cutin biosynthesis|up regulation of cutin synthesis|positive regulation of cutin synthesis|activation of cutin anabolism|up regulation of cutin formation|positive regulation of cutin biosynthesis|positive regulation of cutin formation|up regulation of cutin biosynthesis|up regulation of cutin biosynthetic process|activation of cutin synthesis|up-regulation of cutin anabolism|activation of cutin formation|up-regulation of cutin synthesis http://purl.obolibrary.org/obo/GO_1901959 UBERON:0003619 biolink:AnatomicalEntity aorta tunica intima The innermost layer of the aorta, containing the endothelium and an inner elastic membrane. go-plus.json dorsal aorta tunica intima|tunica intima of trunk of aortic tree|tunica intima of aorta|tunica intima of adult aorta|trunk of aortic tree tunica intima|tunica intima of dorsal aorta|adult aorta tunica intima http://purl.obolibrary.org/obo/UBERON_0003619 CHEBI:22496 biolink:ChemicalSubstance aminobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_22496 UBERON:0003616 biolink:AnatomicalEntity bronchus elastic tissue An elastic tissue that is part of a bronchus [Automatically generated definition]. go-plus.json bronchial trunk elastic tissue|elastic tissue of bronchi|elastic tissue of bronchial trunk|bronchi elastic tissue|textus connectivus elasticus of bronchi|textus connectivus elasticus of bronchial trunk|textus connectivus elasticus of bronchus|elastic tissue of bronchus|elastic connective tissue of bronchus|bronchi elastic connective tissue|bronchus textus connectivus elasticus|bronchial trunk elastic connective tissue|elastic connective tissue of bronchi|bronchial trunk textus connectivus elasticus|elastic connective tissue of bronchial trunk|bronchus elastic connective tissue|bronchi textus connectivus elasticus http://purl.obolibrary.org/obo/UBERON_0003616 GO:1901956 biolink:BiologicalProcess positive regulation of retrograde dense core granule transport Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport. go-plus.json up regulation of retrograde dense core granule transport|activation of retrograde dense core granule transport|up-regulation of retrograde dense core granule transport|upregulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_1901956 UBERON:0003617 biolink:AnatomicalEntity trachea elastic tissue An elastic tissue that is part of a trachea [Automatically generated definition]. go-plus.json windpipe textus connectivus elasticus|windpipe elastic tissue|textus connectivus elasticus of windpipe|cartilaginous trachea textus connectivus elasticus|cartilaginous trachea elastic connective tissue|elastic tissue of windpipe|elastic connective tissue of cartilaginous trachea|textus connectivus elasticus of vertebrate trachea|cartilaginous trachea elastic tissue|elastic connective tissue of windpipe|elastic tissue of vertebrate trachea|elastic tissue of cartilaginous trachea|elastic connective tissue of vertebrate trachea|textus connectivus elasticus of cartilaginous trachea|windpipe elastic connective tissue|vertebrate trachea textus connectivus elasticus|vertebrate trachea elastic connective tissue|vertebrate trachea elastic tissue http://purl.obolibrary.org/obo/UBERON_0003617 GO:1901957 biolink:BiologicalProcess regulation of cutin biosynthetic process Any process that modulates the frequency, rate or extent of cutin biosynthetic process. go-plus.json regulation of cutin anabolism|regulation of cutin synthesis|regulation of cutin formation|regulation of cutin biosynthesis http://purl.obolibrary.org/obo/GO_1901957 UBERON:0003614 biolink:AnatomicalEntity blood vessel elastic tissue Elastic tissue layer that lines a blood vessel layer. go-plus.json vascular elastic laminae|textus connectivus elasticus of blood vessel|blood vessel textus connectivus elasticus|elastic tissue of blood vessel|elastic connective tissue of blood vessel|vascular elastic tissue|vascular elastic lamina|elastic laminae|blood vessel elastic connective tissue|elastic lamina http://purl.obolibrary.org/obo/UBERON_0003614 GO:1901954 biolink:BiologicalProcess regulation of retrograde dense core granule transport Any process that modulates the frequency, rate or extent of retrograde dense core granule transport. go-plus.json http://purl.obolibrary.org/obo/GO_1901954 GO:1901955 biolink:BiologicalProcess negative regulation of retrograde dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport. go-plus.json downregulation of retrograde dense core granule transport|down-regulation of retrograde dense core granule transport|inhibition of retrograde dense core granule transport|down regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_1901955 UBERON:0003615 biolink:AnatomicalEntity lung elastic tissue Elastic tissue that is part of a lung [Automatically generated definition]. go-plus.json elastic tissue of lung|elastic connective tissue of lung|lung textus connectivus elasticus|lung elastic connective tissue|pulmonary elastic fiber|textus connectivus elasticus of lung http://purl.obolibrary.org/obo/UBERON_0003615 GO:1901952 biolink:BiologicalProcess negative regulation of anterograde dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport. go-plus.json down-regulation of anterograde dense core granule transport|downregulation of anterograde dense core granule transport|down regulation of anterograde dense core granule transport|inhibition of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1901952 GO:0045468 biolink:BiologicalProcess regulation of R8 cell spacing in compound eye Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc. go-plus.json regulation of R8 spacing|R8 cell spacing in compound eye http://purl.obolibrary.org/obo/GO_0045468 GO:0045469 biolink:BiologicalProcess negative regulation of R8 cell spacing in compound eye Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye. go-plus.json down-regulation of R8 spacing|downregulation of R8 spacing|down regulation of R8 spacing|inhibition of R8 spacing http://purl.obolibrary.org/obo/GO_0045469 GO:1901953 biolink:BiologicalProcess positive regulation of anterograde dense core granule transport Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport. go-plus.json up-regulation of anterograde dense core granule transport|activation of anterograde dense core granule transport|up regulation of anterograde dense core granule transport|upregulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1901953 CHEBI:22490 biolink:ChemicalSubstance aminoadipate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_22490 GO:1901950 biolink:BiologicalProcess dense core granule transport The directed movement a dense core granule within a cell. go-plus.json dense core vesicle transport http://purl.obolibrary.org/obo/GO_1901950 GO:0045466 biolink:BiologicalProcess R7 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0045466 GO:0045467 biolink:BiologicalProcess R7 cell development The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium. go-plus.json http://purl.obolibrary.org/obo/GO_0045467 GO:1901951 biolink:BiologicalProcess regulation of anterograde dense core granule transport Any process that modulates the frequency, rate or extent of anterograde dense core granule transport. go-plus.json http://purl.obolibrary.org/obo/GO_1901951 GO:0045464 biolink:BiologicalProcess R8 cell fate specification The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0045464 CHEBI:22493 biolink:ChemicalSubstance aminobenzenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22493 GO:0045465 biolink:BiologicalProcess R8 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0045465 CHEBI:22494 biolink:ChemicalSubstance aminobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22494 GO:0045462 biolink:MolecularActivity trichothecene 3-O-acetyltransferase activity Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0045462 GO:0045463 biolink:BiologicalProcess R8 cell development The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium. go-plus.json http://purl.obolibrary.org/obo/GO_0045463 CHEBI:22492 biolink:ChemicalSubstance amino aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_22492 GO:0070408 biolink:BiologicalProcess carbamoyl phosphate metabolic process The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways. UM-BBD_pathwayID:bzn go-plus.json carbamoyl phosphate metabolism http://purl.obolibrary.org/obo/GO_0070408 GO:0070409 biolink:BiologicalProcess carbamoyl phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways. go-plus.json carbamoyl phosphate anabolism|carbamoyl phosphate synthesis|carbamoyl phosphate formation|carbamyl phosphate biosynthetic process|carbamoyl phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0070409 GO:0070406 biolink:MolecularActivity glutamine binding Binding to glutamine, 2,5-diamino-5-oxopentanoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070406 GO:0070407 biolink:BiologicalProcess oxidation-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein. go-plus.json oxidation-dependent protein breakdown|oxidation-dependent proteolysis|oxidized protein catabolic process|oxidation-dependent protein degradation|oxidation-dependent protein catabolism http://purl.obolibrary.org/obo/GO_0070407 GO:0070404 biolink:MolecularActivity NADH binding Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions. go-plus.json reduced nicotinamide adenine dinucleotide binding|reduced NAD binding|NAD (reduced) binding http://purl.obolibrary.org/obo/GO_0070404 GO:0070405 biolink:MolecularActivity ammonium ion binding Binding to ammonium ions (NH4+). go-plus.json ammonium binding http://purl.obolibrary.org/obo/GO_0070405 GO:0070402 biolink:MolecularActivity NADPH binding Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. go-plus.json NADP (reduced) binding|reduced nicotinamide adenine dinucleotide phosphate binding|reduced NADP binding http://purl.obolibrary.org/obo/GO_0070402 GO:0070403 biolink:MolecularActivity NAD+ binding Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions. go-plus.json NAD (oxidized) binding|NAD binding|oxidized nicotinamide adenine dinucleotide binding|oxidized NAD binding http://purl.obolibrary.org/obo/GO_0070403 GO:0070400 biolink:BiologicalProcess teichoic acid D-alanylation The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid. go-plus.json teichoic acid alanylation http://purl.obolibrary.org/obo/GO_0070400 GO:0070401 biolink:MolecularActivity NADP+ binding Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. go-plus.json NADP binding|NADP (oxidized) binding|oxidized NADP binding|oxidized nicotinamide adenine dinucleotide phosphate binding http://purl.obolibrary.org/obo/GO_0070401 CHEBI:71402 biolink:ChemicalSubstance 3-phosphonatopyruvate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71402 chebi_ph7_3 CHEBI:71403 biolink:ChemicalSubstance 8-oxo-dAMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_71403 CHEBI:71406 biolink:ChemicalSubstance (R)-adrenaline(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71406 chebi_ph7_3 CHEBI:71407 biolink:ChemicalSubstance 3-oxooctadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71407 chebi_ph7_3 CHEBI:71408 biolink:ChemicalSubstance 3-hydroxyoctadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71408 chebi_ph7_3 CHEBI:71409 biolink:ChemicalSubstance (beta-L-Ara4N)2-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_71409 NCBITaxon:226900 biolink:OrganismalEntity Bacillus cereus ATCC 14579 go-plus.json Bacillus cereus (strain ATCC 14579 / DSM 31) http://purl.obolibrary.org/obo/NCBITaxon_226900 CHEBI:71410 biolink:ChemicalSubstance 7-methyl-3-oxooct-6-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71410 chebi_ph7_3 CHEBI:71412 biolink:ChemicalSubstance trans-2-octadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71412 chebi_ph7_3 CHEBI:71427 biolink:ChemicalSubstance isotridecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71427 chebi_ph7_3 CHEBI:71429 biolink:ChemicalSubstance deaminoneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71429 CHEBI:71435 biolink:ChemicalSubstance 3-hydroxyisopentadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71435 chebi_ph7_3 CHEBI:71437 biolink:ChemicalSubstance isotridecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71437 CHEBI:71439 biolink:ChemicalSubstance 3-oxoisopentadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71439 CHEBI:71430 biolink:ChemicalSubstance 3-oxoisopentadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71430 chebi_ph7_3 CHEBI:71443 biolink:ChemicalSubstance 3-hydroxyisopentadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71443 CHEBI:537519 biolink:ChemicalSubstance L-aspartic acid 4-semialdehyde zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_537519 chebi_ph7_3 CHEBI:71445 biolink:ChemicalSubstance 3-oxoisoheptadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71445 chebi_ph7_3 CHEBI:71446 biolink:ChemicalSubstance 3-hydroxyisoheptadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71446 chebi_ph7_3 CHEBI:71449 biolink:ChemicalSubstance hexadec-9-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71449 chebi_ph7_3 CHEBI:141790 biolink:ChemicalSubstance 3-hydroxybutane-1,2,3-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_141790 chebi_ph7_3 CHEBI:71453 biolink:ChemicalSubstance 3-oxoisoheptadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71453 CHEBI:71455 biolink:ChemicalSubstance 3-hydroxyicosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71455 chebi_ph7_3 CHEBI:71456 biolink:ChemicalSubstance 3-hydroxydocosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71456 chebi_ph7_3 CHEBI:71451 biolink:ChemicalSubstance 3-oxodocosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71451 chebi_ph7_3 CHEBI:71464 biolink:ChemicalSubstance palmitoyl ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71464 chebi_ph7_3 CHEBI:71465 biolink:ChemicalSubstance palmitoleoyl ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71465 chebi_ph7_3 CHEBI:71466 biolink:ChemicalSubstance oleoyl ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71466 chebi_ph7_3 CHEBI:71467 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z,17Z)-icosapentaenoylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71467 chebi_ph7_3 CHEBI:141772 biolink:ChemicalSubstance 2-hydroxydodecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_141772 chebi_ph7_3 CHEBI:71460 biolink:ChemicalSubstance (E)-isopentadec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71460 chebi_ph7_3 CHEBI:71461 biolink:ChemicalSubstance isoheptadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71461 chebi_ph7_3 CHEBI:71462 biolink:ChemicalSubstance (E)-isoheptadec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71462 chebi_ph7_3 GO:0070394 biolink:BiologicalProcess lipoteichoic acid metabolic process The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. go-plus.json LTA metabolic process|lipoteichoic acid metabolism http://purl.obolibrary.org/obo/GO_0070394 GO:0070395 biolink:BiologicalProcess lipoteichoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. go-plus.json lipoteichoic acid biosynthesis|lipoteichoic acid anabolism|lipoteichoic acid synthesis|LTA biosynthetic process|lipoteichoic acid formation http://purl.obolibrary.org/obo/GO_0070395 GO:0070392 biolink:BiologicalProcess detection of lipoteichoic acid The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. go-plus.json detection of LTA http://purl.obolibrary.org/obo/GO_0070392 GO:0070393 biolink:BiologicalProcess teichoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues. go-plus.json teichoic acid degradation|teichoic acid breakdown|teichoic acid catabolism http://purl.obolibrary.org/obo/GO_0070393 GO:0070390 biolink:CellularComponent transcription export complex 2 A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p. go-plus.json TREX-2 complex|Sac3-Thp1-Sus1-Sem1-Cdc31 complex http://purl.obolibrary.org/obo/GO_0070390 GO:0070391 biolink:BiologicalProcess response to lipoteichoic acid Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. go-plus.json response to LTA http://purl.obolibrary.org/obo/GO_0070391 GO:0070398 biolink:BiologicalProcess wall teichoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan. go-plus.json wall teichoic acid anabolism|wall teichoic acid biosynthesis|wall teichoic acid synthesis|wall teichoic acid formation|WTA biosynthetic process http://purl.obolibrary.org/obo/GO_0070398 GO:0070399 biolink:BiologicalProcess wall teichoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan. go-plus.json wall teichoic acid breakdown|wall teichoic acid catabolism|wall teichoic acid degradation http://purl.obolibrary.org/obo/GO_0070399 GO:0070396 biolink:BiologicalProcess lipoteichoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. go-plus.json lipoteichoic acid degradation|lipoteichoic acid catabolism|lipoteichoic acid breakdown http://purl.obolibrary.org/obo/GO_0070396 GO:0070397 biolink:BiologicalProcess wall teichoic acid metabolic process The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan. go-plus.json wall teichoic acid metabolism|WTA metabolic process http://purl.obolibrary.org/obo/GO_0070397 GO:0070383 biolink:BiologicalProcess DNA cytosine deamination The removal of an amino group from a cytosine residue in DNA, forming a uracil residue. go-plus.json http://purl.obolibrary.org/obo/GO_0070383 GO:0070384 biolink:BiologicalProcess Harderian gland development The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species. go-plus.json http://purl.obolibrary.org/obo/GO_0070384 GO:0070381 biolink:CellularComponent endosome to plasma membrane transport vesicle A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane and to release various cargo molecules, such as proteins or hormones, by exocytosis. go-plus.json endosome to plasma membrane constitutive secretory pathway transport vesicle|endosome-plasma membrane transport vesicle http://purl.obolibrary.org/obo/GO_0070381 GO:0070382 biolink:CellularComponent exocytic vesicle A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. go-plus.json exocytotic vesicle|exocytic constitutive secretory pathway transport vesicle http://purl.obolibrary.org/obo/GO_0070382 GO:0070380 biolink:MolecularActivity high mobility group box 1 receptor activity Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json HMGB1 receptor activity http://purl.obolibrary.org/obo/GO_0070380 GO:0070389 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070389 GO:0070387 biolink:CellularComponent procollagen-proline 4-dioxygenase complex, alpha(II) type A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations. go-plus.json prolyl 4-hydroxylase complex (alpha(II)-type)|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(II) type http://purl.obolibrary.org/obo/GO_0070387 GO:0070388 biolink:CellularComponent procollagen-proline 4-dioxygenase complex, alpha(III) type A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform. go-plus.json procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(III) type|prolyl 4-hydroxylase complex (alpha(III)-type) http://purl.obolibrary.org/obo/GO_0070388 GO:0070385 biolink:CellularComponent egasyn-beta-glucuronidase complex A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0070385 GO:0070386 biolink:CellularComponent procollagen-proline 4-dioxygenase complex, alpha(I) type A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline). go-plus.json procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(I) type|prolyl 4-hydroxylase complex (alpha(I)-type) http://purl.obolibrary.org/obo/GO_0070386 UBERON:0037089 biolink:AnatomicalEntity wall of orbit go-plus.json orbit wall http://purl.obolibrary.org/obo/UBERON_0037089 UBERON:0037094 biolink:AnatomicalEntity wall of common carotid artery go-plus.json common carotid arterial wall http://purl.obolibrary.org/obo/UBERON_0037094 UBERON:0013069 biolink:AnatomicalEntity popliteal area A depression on the ventral side of the femur, at the knee joint, between the condyles. go-plus.json popliteal region|popliteal fossa|knee pit|popliteal space http://purl.obolibrary.org/obo/UBERON_0013069 GO:0045350 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045350 GO:0045351 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045351 GO:1901848 biolink:BiologicalProcess nicotinate catabolic process The chemical reactions and pathways resulting in the breakdown of nicotinate. go-plus.json nicotinate catabolism|nicotinate degradation|nicotinate breakdown http://purl.obolibrary.org/obo/GO_1901848 GO:1901849 biolink:BiologicalProcess nicotinate biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinate. go-plus.json nicotinate biosynthesis|nicotinate anabolism|nicotinate synthesis|nicotinate formation http://purl.obolibrary.org/obo/GO_1901849 GO:1901846 biolink:BiologicalProcess positive regulation of cell communication by electrical coupling involved in cardiac conduction Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. go-plus.json upregulation of cell communication by electrical coupling involved in cardiac conduction|up-regulation of cell communication by electrical coupling involved in cardiac conduction|activation of cell communication by electrical coupling involved in cardiac conduction|up regulation of cell communication by electrical coupling involved in cardiac conduction http://purl.obolibrary.org/obo/GO_1901846 GO:1901847 biolink:BiologicalProcess nicotinate metabolic process The chemical reactions and pathways involving nicotinate. go-plus.json nicotinate metabolism http://purl.obolibrary.org/obo/GO_1901847 CHEBI:22469 biolink:ChemicalSubstance alpha-terpineol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22469 chebi_ph7_3 GO:1901844 biolink:BiologicalProcess regulation of cell communication by electrical coupling involved in cardiac conduction Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. go-plus.json http://purl.obolibrary.org/obo/GO_1901844 GO:1901845 biolink:BiologicalProcess negative regulation of cell communication by electrical coupling involved in cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. go-plus.json downregulation of cell communication by electrical coupling involved in cardiac conduction|down regulation of cell communication by electrical coupling involved in cardiac conduction|inhibition of cell communication by electrical coupling involved in cardiac conduction|down-regulation of cell communication by electrical coupling involved in cardiac conduction http://purl.obolibrary.org/obo/GO_1901845 GO:0045358 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045358 GO:1901842 biolink:BiologicalProcess negative regulation of high voltage-gated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity. go-plus.json negative regulation of high voltage gated calcium channel activity|down-regulation of high voltage gated calcium channel activity|inhibition of high voltage-dependent calcium channel activity|down regulation of high voltage-gated calcium channel activity|downregulation of high voltage-gated calcium channel activity|inhibition of high voltage gated calcium channel activity|down regulation of high voltage-dependent calcium channel activity|downregulation of high voltage-dependent calcium channel activity|down regulation of high voltage gated calcium channel activity|down-regulation of high voltage-gated calcium channel activity|downregulation of high voltage gated calcium channel activity|down-regulation of high voltage-dependent calcium channel activity|negative regulation of high voltage-dependent calcium channel activity|inhibition of high voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901842 GO:1901843 biolink:BiologicalProcess positive regulation of high voltage-gated calcium channel activity Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity. go-plus.json positive regulation of high voltage gated calcium channel activity|up-regulation of high voltage-dependent calcium channel activity|activation of high voltage gated calcium channel activity|upregulation of high voltage-gated calcium channel activity|up-regulation of high voltage gated calcium channel activity|upregulation of high voltage-dependent calcium channel activity|up regulation of high voltage-gated calcium channel activity|activation of high voltage-gated calcium channel activity|upregulation of high voltage gated calcium channel activity|up regulation of high voltage-dependent calcium channel activity|positive regulation of high voltage-dependent calcium channel activity|up regulation of high voltage gated calcium channel activity|activation of high voltage-dependent calcium channel activity|up-regulation of high voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901843 GO:0045359 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045359 GO:0045356 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045356 GO:1901840 biolink:BiologicalProcess negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding. go-plus.json down-regulation of RNA polymerase I regulatory region sequence-specific DNA binding|downregulation of RNA polymerase I regulatory region sequence-specific DNA binding|down regulation of RNA polymerase I regulatory region sequence-specific DNA binding|inhibition of RNA polymerase I regulatory region sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_1901840 GO:1901841 biolink:BiologicalProcess regulation of high voltage-gated calcium channel activity Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity. go-plus.json regulation of high voltage-dependent calcium channel activity|regulation of high voltage gated calcium channel activity http://purl.obolibrary.org/obo/GO_1901841 GO:0045357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045357 GO:0045354 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045354 GO:0045355 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045355 GO:0045352 biolink:MolecularActivity interleukin-1 type I receptor antagonist activity Blocks the binding of interleukin-1 to interleukin-1 type I receptors. go-plus.json IL-1ra type I http://purl.obolibrary.org/obo/GO_0045352 CHEBI:46430 biolink:ChemicalSubstance (-)-alpha-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_46430 chebi_ph7_3 GO:0060990 biolink:BiologicalProcess lipid tube assembly involved in organelle fission The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission. go-plus.json lipid tubulation involved in organelle fission http://purl.obolibrary.org/obo/GO_0060990 GO:0045353 biolink:MolecularActivity interleukin-1 type II receptor antagonist activity Blocks the binding of interleukin-1 to interleukin-1 type II receptors. go-plus.json IL-1ra type II http://purl.obolibrary.org/obo/GO_0045353 GO:0060991 biolink:BiologicalProcess obsolete lipid tube assembly involved in cytokinesis OBSOLETE. The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis. go-plus.json lipid tube assembly involved in cytokinesis|lipid tubulation involved in cytokinesis http://purl.obolibrary.org/obo/GO_0060991 UBERON:0003692 biolink:AnatomicalEntity acromioclavicular joint Any joint connecting the acromonion of the scapula and clavicle. go-plus.json acromioclavicular articulation|articulatio acromioclavicularis|scapuloclavicular articulation http://purl.obolibrary.org/obo/UBERON_0003692 UBERON:0003693 biolink:AnatomicalEntity retroperitoneal space Anatomical space in the abdominal cavity behind (retro) the peritoneum. It has no specific delineating anatomical structures. Organs are retroperitoneal if they only have peritoneum on their anterior side. go-plus.json retroperitoneum|spatium retroperitoneale http://purl.obolibrary.org/obo/UBERON_0003693 GO:0060992 biolink:BiologicalProcess response to fungicide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0060992 GO:0060993 biolink:BiologicalProcess kidney morphogenesis Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0060993 UBERON:0003691 biolink:AnatomicalEntity epidural space The outermost part of the spinal canal. It is the space within the canal (formed by the surrounding vertebrae) lying outside the dura mater. go-plus.json spatium epidurale|cavum epidurale|epidural cavity|extradural space|spatium extradurale|cavum extradurale http://purl.obolibrary.org/obo/UBERON_0003691 GO:0060994 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in kidney development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060994 GO:0060995 biolink:BiologicalProcess cell-cell signaling involved in kidney development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ. go-plus.json cell-cell signalling involved in kidney development http://purl.obolibrary.org/obo/GO_0060995 GO:0070318 biolink:BiologicalProcess positive regulation of G0 to G1 transition A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase. go-plus.json http://purl.obolibrary.org/obo/GO_0070318 GO:0070319 biolink:CellularComponent Golgi to plasma membrane transport vesicle A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. go-plus.json Golgi to plasma membrane constitutive secretory pathway transport vesicle|Golgi-plasma membrane transport vesicle http://purl.obolibrary.org/obo/GO_0070319 GO:0060996 biolink:BiologicalProcess dendritic spine development The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0060996 GO:0060997 biolink:BiologicalProcess dendritic spine morphogenesis The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0060997 GO:0070316 biolink:BiologicalProcess regulation of G0 to G1 transition A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase. go-plus.json http://purl.obolibrary.org/obo/GO_0070316 GO:0070317 biolink:BiologicalProcess negative regulation of G0 to G1 transition A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase. go-plus.json maintenance of G0 arrest|maintenance of G0 phase|maintenance of cell quiescence|maintenance of cell cycle quiescence http://purl.obolibrary.org/obo/GO_0070317 GO:0060998 biolink:BiologicalProcess regulation of dendritic spine development Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060998 GO:0070314 biolink:BiologicalProcess G1 to G0 transition A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence. go-plus.json establishment of cell quiescence|cell cycle quiescence|stationary phase|G1/G0 transition http://purl.obolibrary.org/obo/GO_0070314 GO:0060999 biolink:BiologicalProcess positive regulation of dendritic spine development Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060999 GO:0070315 biolink:BiologicalProcess G1 to G0 transition involved in cell differentiation A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation. go-plus.json G1/G0 transition involved in cell differentiation http://purl.obolibrary.org/obo/GO_0070315 GO:0070312 biolink:CellularComponent RAD52-ERCC4-ERCC1 complex A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070312 GO:0070313 biolink:CellularComponent RGS6-DNMT1-DMAP1 complex A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1. go-plus.json http://purl.obolibrary.org/obo/GO_0070313 GO:0070310 biolink:CellularComponent ATR-ATRIP complex A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A. go-plus.json Mec1-Lcd1 complex|Rad3-Rad26 complex http://purl.obolibrary.org/obo/GO_0070310 UBERON:0003696 biolink:AnatomicalEntity metatarsophalangeal joint The metatarsophalangeal articulations are the joints between the metatarsal bones of the foot and the proximal bones of the toes . They are condyloid joints meaning an elliptical or rounded surface (of the metatarsal bones) come close to the shallow cavities (of the proximal phalanges). The ligaments are the plantar and two collateral. go-plus.json metatarsophalangeal articulation|metatarsal joint|metatarsalphalangeal joint|articulationes metatarsophalangeae|metatarsal-phalangeal joint|metatarsophalangeal http://purl.obolibrary.org/obo/UBERON_0003696 UBERON:0003697 biolink:AnatomicalEntity abdominal wall The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. go-plus.json layers of the abdominal wall|paries abdominalis|wall of abdomen proper|wall of abdomen|abdominal wall proper|paries abdominalis http://purl.obolibrary.org/obo/UBERON_0003697 GO:0070311 biolink:CellularComponent nucleosomal methylation activator complex A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription. go-plus.json NUMAC http://purl.obolibrary.org/obo/GO_0070311 UBERON:0003694 biolink:AnatomicalEntity atlanto-axial joint The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas. go-plus.json lateral atlanto-axial joint|atlanto axial joint|atlantoaxial joint|median atlanto-axial joint|articulatio atlantoepistrophica|atlantoaxial|articulatio atlantoaxialis http://purl.obolibrary.org/obo/UBERON_0003694 UBERON:0003695 biolink:AnatomicalEntity metacarpophalangeal joint The metacarpophalangeal joints (MCP) are of the condyloid kind, formed by the reception of the rounded heads of the metacarpal bones into shallow cavities on the proximal ends of the first phalanges, with the exception of that of the thumb, which presents more of the characters of a ginglymoid joint. Arthritis of the MCP is a distinguishing feature of Rheumatoid Arthritis, as opposed to the distal interphalangeal joint in osteoarthritis. [WP,unvetted]. go-plus.json MP joint|metacarpal joint|articulationes metacarpophalangeae|carpometacarpophalangeal joint|metacarpo-phalangeal joint|metacarpal phalangeal joint http://purl.obolibrary.org/obo/UBERON_0003695 CHEBI:22475 biolink:ChemicalSubstance amino acid amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22475 GO:0045361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045361 GO:0045362 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045362 GO:1901859 biolink:BiologicalProcess negative regulation of mitochondrial DNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. go-plus.json downregulation of mtDNA metabolic process|downregulation of mitochondrial DNA metabolism|down regulation of mitochondrial DNA metabolism|negative regulation of mtDNA metabolism|down-regulation of mtDNA metabolism|negative regulation of mtDNA metabolic process|down-regulation of mtDNA metabolic process|down regulation of mitochondrial DNA metabolic process|inhibition of mitochondrial DNA metabolism|downregulation of mitochondrial DNA metabolic process|downregulation of mtDNA metabolism|down regulation of mtDNA metabolism|inhibition of mtDNA metabolic process|down-regulation of mitochondrial DNA metabolic process|down-regulation of mitochondrial DNA metabolism|negative regulation of mitochondrial DNA metabolism|inhibition of mtDNA metabolism|down regulation of mtDNA metabolic process|inhibition of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_1901859 GO:0045360 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045360 CHEBI:22479 biolink:ChemicalSubstance amino cyclitol glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_22479 GO:1901857 biolink:BiologicalProcess positive regulation of cellular respiration Any process that activates or increases the frequency, rate or extent of cellular respiration. go-plus.json up regulation of respiration|positive regulation of respiration|upregulation of oxidative metabolism|upregulation of oxidative metabolic process|upregulation of cellular respiration|activation of respiration|up-regulation of oxidative metabolism|up regulation of oxidative metabolic process|up-regulation of respiration|activation of cellular respiration|up-regulation of cellular respiration|positive regulation of oxidative metabolic process|activation of oxidative metabolism|activation of oxidative metabolic process|upregulation of respiration|positive regulation of oxidative metabolism|up regulation of oxidative metabolism|up-regulation of oxidative metabolic process|up regulation of cellular respiration http://purl.obolibrary.org/obo/GO_1901857 GO:1901858 biolink:BiologicalProcess regulation of mitochondrial DNA metabolic process Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process. go-plus.json regulation of mitochondrial DNA metabolism|regulation of mtDNA metabolism|regulation of mtDNA metabolic process http://purl.obolibrary.org/obo/GO_1901858 GO:1901855 biolink:BiologicalProcess 5,6,7,8-tetrahydrosarcinapterin biosynthetic process The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin. go-plus.json 5,6,7,8-tetrahydrosarcinapterin anabolism|5,6,7,8-tetrahydrosarcinapterin synthesis|5,6,7,8-tetrahydrosarcinapterin formation|5,6,7,8-tetrahydrosarcinapterin biosynthesis http://purl.obolibrary.org/obo/GO_1901855 GO:1901856 biolink:BiologicalProcess negative regulation of cellular respiration Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration. go-plus.json downregulation of respiration|downregulation of cellular respiration|inhibition of oxidative metabolic process|down regulation of oxidative metabolism|down regulation of cellular respiration|inhibition of cellular respiration|down regulation of oxidative metabolic process|negative regulation of respiration|down-regulation of respiration|inhibition of oxidative metabolism|downregulation of oxidative metabolic process|inhibition of respiration|negative regulation of oxidative metabolism|down-regulation of oxidative metabolism|negative regulation of oxidative metabolic process|down-regulation of oxidative metabolic process|down-regulation of cellular respiration|down regulation of respiration|downregulation of oxidative metabolism http://purl.obolibrary.org/obo/GO_1901856 CHEBI:22478 biolink:ChemicalSubstance amino alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22478 GO:1901853 biolink:BiologicalProcess 5,6,7,8-tetrahydrosarcinapterin metabolic process The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin. go-plus.json 5,6,7,8-tetrahydrosarcinapterin metabolism http://purl.obolibrary.org/obo/GO_1901853 GO:0045369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045369 GO:1901854 biolink:BiologicalProcess 5,6,7,8-tetrahydrosarcinapterin catabolic process The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin. go-plus.json 5,6,7,8-tetrahydrosarcinapterin catabolism|5,6,7,8-tetrahydrosarcinapterin degradation|5,6,7,8-tetrahydrosarcinapterin breakdown http://purl.obolibrary.org/obo/GO_1901854 GO:1901851 biolink:BiologicalProcess 7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin. go-plus.json coenzyme F0 catabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin degradation|coenzyme F0 degradation|7,8-didemethyl-8-hydroxy-5-deazariboflavin breakdown|coenzyme F0 breakdown|coenzyme F0 catabolic process http://purl.obolibrary.org/obo/GO_1901851 GO:0045367 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045367 GO:1901852 biolink:BiologicalProcess 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin. go-plus.json coenzyme F0 anabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin synthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin formation|coenzyme F0 synthesis|coenzyme F0 formation|coenzyme F0 biosynthesis|coenzyme F0 biosynthetic process|7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin anabolism http://purl.obolibrary.org/obo/GO_1901852 GO:0045368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045368 GO:0045365 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045365 GO:1901850 biolink:BiologicalProcess 7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin. go-plus.json coenzyme F0 metabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolism http://purl.obolibrary.org/obo/GO_1901850 GO:0045366 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045366 GO:0045363 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045363 CHEBI:22470 biolink:ChemicalSubstance alpha-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_22470 GO:0045364 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045364 GO:0060980 biolink:BiologicalProcess cell migration involved in coronary vasculogenesis The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0060980 UBERON:0003682 biolink:AnatomicalEntity palatal muscle The muscles of the palate are the glossopalatine, palatoglossus, levator palati(ni), musculus uvulae, palatopharyngeus, and tensor palati(ni). go-plus.json musculi palati mollis et faucium|palate muscle|palatal muscle|musculi palati mollis et faucium|muscle of palate|palatine muscle http://purl.obolibrary.org/obo/UBERON_0003682 GO:0060981 biolink:BiologicalProcess cell migration involved in coronary angiogenesis The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0060981 GO:0070309 biolink:BiologicalProcess lens fiber cell morphogenesis The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. go-plus.json lens fibre cell morphogenesis|elongation of lens fiber cell|lens fiber cell morphogenesis during differentiation http://purl.obolibrary.org/obo/GO_0070309 GO:0060982 biolink:BiologicalProcess coronary artery morphogenesis The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0060982 GO:0060983 biolink:BiologicalProcess epicardium-derived cardiac vascular smooth muscle cell differentiation The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0060983 GO:0070307 biolink:BiologicalProcess lens fiber cell development The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. go-plus.json lens fibre cell development http://purl.obolibrary.org/obo/GO_0070307 GO:0060984 biolink:BiologicalProcess epicardium-derived cardiac vascular smooth muscle cell development The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0060984 GO:0070308 biolink:BiologicalProcess lens fiber cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. go-plus.json lens fibre cell fate commitment http://purl.obolibrary.org/obo/GO_0070308 GO:0060985 biolink:BiologicalProcess epicardium-derived cardiac vascular smooth muscle cell fate commitment The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060985 GO:0060986 biolink:BiologicalProcess endocrine hormone secretion The regulated release of a hormone into the circulatory system. go-plus.json http://purl.obolibrary.org/obo/GO_0060986 GO:0070305 biolink:BiologicalProcess response to cGMP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus. go-plus.json response to 3',5'-cGMP|response to cyclic GMP|response to 3',5' cGMP|response to guanosine 3',5'-cyclophosphate http://purl.obolibrary.org/obo/GO_0070305 GO:0060987 biolink:CellularComponent lipid tube A macromolecular complex that contains a tube of lipid surrounded by a protein coat. go-plus.json http://purl.obolibrary.org/obo/GO_0060987 GO:0070306 biolink:BiologicalProcess lens fiber cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. go-plus.json lens fibre cell differentiation http://purl.obolibrary.org/obo/GO_0070306 GO:0070303 biolink:BiologicalProcess negative regulation of stress-activated protein kinase signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade. go-plus.json negative regulation of stress-activated protein kinase signaling pathway|down-regulation of stress-activated protein kinase signaling pathway|negative regulation of SAPK signaling pathway|inhibition of stress-activated protein kinase signaling pathway|negative regulation of stress-activated protein kinase signalling pathway|down regulation of stress-activated protein kinase signaling pathway|downregulation of stress-activated protein kinase signaling pathway http://purl.obolibrary.org/obo/GO_0070303 GO:0060988 biolink:BiologicalProcess lipid tube assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission. go-plus.json lipid tubulation http://purl.obolibrary.org/obo/GO_0060988 GO:0070304 biolink:BiologicalProcess positive regulation of stress-activated protein kinase signaling cascade Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade. go-plus.json stimulation of stress-activated protein kinase signaling pathway|up-regulation of stress-activated protein kinase signaling pathway|positive regulation of SAPK signaling pathway|upregulation of stress-activated protein kinase signaling pathway|positive regulation of stress-activated protein kinase signalling pathway|positive regulation of stress-activated protein kinase signaling pathway|up regulation of stress-activated protein kinase signaling pathway|activation of stress-activated protein kinase signaling pathway http://purl.obolibrary.org/obo/GO_0070304 GO:0060989 biolink:BiologicalProcess lipid tube assembly involved in organelle fusion The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse. go-plus.json lipid tubulation involved in organelle fusion http://purl.obolibrary.org/obo/GO_0060989 GO:0070301 biolink:BiologicalProcess cellular response to hydrogen peroxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0070301 UBERON:0003687 biolink:AnatomicalEntity foramen magnum In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003687 GO:0070302 biolink:BiologicalProcess regulation of stress-activated protein kinase signaling cascade Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade. go-plus.json regulation of SAPK signaling pathway|regulation of stress-activated protein kinase signaling pathway|regulation of stress-activated protein kinase signalling pathway http://purl.obolibrary.org/obo/GO_0070302 UBERON:0003685 biolink:AnatomicalEntity cranial suture Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture. go-plus.json suture joint of skull|cranium suture|suture|sutura|suture of cranium http://purl.obolibrary.org/obo/UBERON_0003685 GO:0070300 biolink:MolecularActivity phosphatidic acid binding Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. go-plus.json phosphatidate binding http://purl.obolibrary.org/obo/GO_0070300 UBERON:0003684 biolink:AnatomicalEntity abdominal cavity The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity). go-plus.json space of abdominal compartment|cavity of compartment of abdomen|cavity of abdominal compartment|cavitas abdominis http://purl.obolibrary.org/obo/UBERON_0003684 GO:0045372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045372 GO:0045373 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045373 GO:0045370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045370 CHEBI:22440 biolink:ChemicalSubstance alpha-N-substituted L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22440 GO:0045371 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045371 GO:1901868 biolink:BiologicalProcess ecgonine methyl ester catabolic process The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester. go-plus.json ecgonine methyl ester degradation|ecgonine methyl ester breakdown|ecgonine methyl ester catabolism http://purl.obolibrary.org/obo/GO_1901868 GO:1901869 biolink:BiologicalProcess ecgonine methyl ester biosynthetic process The chemical reactions and pathways resulting in the formation of ecgonine methyl ester. go-plus.json ecgonine methyl ester formation|ecgonine methyl ester biosynthesis|ecgonine methyl ester anabolism|ecgonine methyl ester synthesis http://purl.obolibrary.org/obo/GO_1901869 GO:1901866 biolink:BiologicalProcess capsorubin biosynthetic process The chemical reactions and pathways resulting in the formation of capsorubin. go-plus.json capsorubin synthesis|capsorubin formation|capsorubin biosynthesis|capsorubin anabolism http://purl.obolibrary.org/obo/GO_1901866 GO:1901867 biolink:BiologicalProcess ecgonine methyl ester metabolic process The chemical reactions and pathways involving ecgonine methyl ester. go-plus.json ecgonine methyl ester metabolism http://purl.obolibrary.org/obo/GO_1901867 CHEBI:22445 biolink:ChemicalSubstance alpha-aspartyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22445 GO:1901864 biolink:BiologicalProcess capsorubin metabolic process The chemical reactions and pathways involving capsorubin. go-plus.json capsorubin metabolism http://purl.obolibrary.org/obo/GO_1901864 GO:1901865 biolink:BiologicalProcess capsorubin catabolic process The chemical reactions and pathways resulting in the breakdown of capsorubin. go-plus.json capsorubin degradation|capsorubin catabolism|capsorubin breakdown http://purl.obolibrary.org/obo/GO_1901865 GO:0045378 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045378 GO:1901862 biolink:BiologicalProcess negative regulation of muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. go-plus.json down regulation of muscle tissue development|downregulation of muscle tissue development|down-regulation of muscle tissue development|inhibition of muscle tissue development http://purl.obolibrary.org/obo/GO_1901862 OBO:GOCHE_76838 biolink:OntologyClass substance with EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76838 3_STAR GO:1901863 biolink:BiologicalProcess positive regulation of muscle tissue development Any process that activates or increases the frequency, rate or extent of muscle tissue development. go-plus.json upregulation of muscle tissue development|up regulation of muscle tissue development|activation of muscle tissue development|up-regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901863 GO:0045379 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045379 GO:1901860 biolink:BiologicalProcess positive regulation of mitochondrial DNA metabolic process Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. go-plus.json upregulation of mtDNA metabolism|activation of mitochondrial DNA metabolism|upregulation of mtDNA metabolic process|positive regulation of mitochondrial DNA metabolism|up-regulation of mitochondrial DNA metabolic process|up regulation of mitochondrial DNA metabolism|up-regulation of mtDNA metabolism|up regulation of mtDNA metabolic process|positive regulation of mtDNA metabolic process|activation of mtDNA metabolism|upregulation of mitochondrial DNA metabolic process|upregulation of mitochondrial DNA metabolism|activation of mtDNA metabolic process|positive regulation of mtDNA metabolism|up regulation of mtDNA metabolism|up-regulation of mtDNA metabolic process|up regulation of mitochondrial DNA metabolic process|activation of mitochondrial DNA metabolic process|up-regulation of mitochondrial DNA metabolism http://purl.obolibrary.org/obo/GO_1901860 GO:0045376 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045376 GO:0045377 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045377 GO:1901861 biolink:BiologicalProcess regulation of muscle tissue development Any process that modulates the frequency, rate or extent of muscle tissue development. go-plus.json http://purl.obolibrary.org/obo/GO_1901861 GO:0045374 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045374 GO:0045375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045375 GO:0070338 biolink:MolecularActivity 5'-flap-structured DNA binding Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers. go-plus.json http://purl.obolibrary.org/obo/GO_0070338 GO:0070339 biolink:BiologicalProcess response to bacterial lipopeptide Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0070339 GO:0070336 biolink:MolecularActivity flap-structured DNA binding Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070336 GO:0070337 biolink:MolecularActivity 3'-flap-structured DNA binding Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070337 GO:0070334 biolink:CellularComponent alpha6-beta4 integrin-laminin 5 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5. go-plus.json alpha6-beta4 integrin-laminin-332 complex|ITGA6-ITGB4-LAMA5 complex http://purl.obolibrary.org/obo/GO_0070334 GO:0070335 biolink:MolecularActivity aspartate binding Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4. go-plus.json aspartic acid binding http://purl.obolibrary.org/obo/GO_0070335 GO:0070332 biolink:CellularComponent CD20-Lck-Lyn-Fyn complex A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn. go-plus.json http://purl.obolibrary.org/obo/GO_0070332 GO:0070333 biolink:CellularComponent alpha6-beta4 integrin-Shc-Grb2 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2. go-plus.json ITGA6-ITGB4-SHC-GRB2 complex http://purl.obolibrary.org/obo/GO_0070333 UBERON:0003672 biolink:AnatomicalEntity dentition A collection of teeth arranged in some pattern in the mouth or other part of the body. The arrangement may be a simple row, a collection of rows, or a more elaborate structure, such as a toooth whorl. go-plus.json teeth set|teeth|teeth|set of teeth|collection of teeth|dentes http://purl.obolibrary.org/obo/UBERON_0003672 GO:0070330 biolink:MolecularActivity aromatase activity Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. RHEA:17149|MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN|EC:1.14.14.1|UM-BBD_enzymeID:e0551 go-plus.json estrogen synthetase activity http://purl.obolibrary.org/obo/GO_0070330 GO:0070331 biolink:CellularComponent CD20-Lck-Fyn complex A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn. go-plus.json http://purl.obolibrary.org/obo/GO_0070331 GO:0045383 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045383 CHEBI:22453 biolink:ChemicalSubstance alpha-glutamyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22453 GO:0045384 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045384 GO:0045381 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045381 GO:0045382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045382 GO:1901879 biolink:BiologicalProcess regulation of protein depolymerization Any process that modulates the frequency, rate or extent of protein depolymerization. go-plus.json regulation of protein polymer catabolism|regulation of protein polymer degradation|regulation of protein polymer breakdown|regulation of protein polymer catabolic process http://purl.obolibrary.org/obo/GO_1901879 GO:0045380 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045380 GO:1901877 biolink:BiologicalProcess negative regulation of calcium ion binding Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding. go-plus.json down-regulation of calcium ion storage activity|negative regulation of calcium ion storage activity|inhibition of calcium ion binding|downregulation of calcium ion storage activity|down regulation of calcium ion storage activity|down regulation of calcium ion binding|inhibition of calcium ion storage activity|downregulation of calcium ion binding|down-regulation of calcium ion binding http://purl.obolibrary.org/obo/GO_1901877 UBERON:0003658 biolink:AnatomicalEntity hip muscle Any muscle organ that is part of a hip [Automatically generated definition]. go-plus.json hip muscle organ|muscle organ of hip region|muscle organ of hip|muscle organ of regio coxae|hip region muscle organ|regio coxae muscle organ http://purl.obolibrary.org/obo/UBERON_0003658 CHEBI:22455 biolink:ChemicalSubstance alpha-hydroxynitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_22455 GO:1901878 biolink:BiologicalProcess positive regulation of calcium ion binding Any process that activates or increases the frequency, rate or extent of calcium ion binding. go-plus.json positive regulation of calcium ion storage activity|up regulation of calcium ion storage activity|up-regulation of calcium ion binding|upregulation of calcium ion binding|upregulation of calcium ion storage activity|up-regulation of calcium ion storage activity|up regulation of calcium ion binding|activation of calcium ion binding|activation of calcium ion storage activity http://purl.obolibrary.org/obo/GO_1901878 UBERON:0003659 biolink:AnatomicalEntity pedal digit muscle Any muscle organ that is part of a toe [Automatically generated definition]. go-plus.json foot digit muscle|muscle organ of terminal segment of free lower limb digit|digit of terminal segment of free lower limb muscle organ|hind limb digit muscle|terminal segment of free lower limb digit muscle organ|foot digit muscle organ|muscle organ of foot digit|muscle organ of digit of terminal segment of free lower limb|muscle organ of toe|digitus pedis muscle organ|digit of foot muscle organ|foot digit muscle|muscle organ of digit of foot|muscle organ of digitus pedis|toe muscle organ http://purl.obolibrary.org/obo/UBERON_0003659 GO:1901875 biolink:BiologicalProcess positive regulation of post-translational protein modification Any process that activates or increases the frequency, rate or extent of post-translational protein modification. go-plus.json up regulation of posttranslational modification|positive regulation of posttranslational protein modification|up regulation of post-translational modification|up regulation of posttranslational protein modification|up-regulation of posttranslational amino acid modification|positive regulation of post-translational modification|up regulation of post-translational protein modification|up regulation of PTM|up-regulation of post-translational amino acid modification|activation of post-translational protein modification|positive regulation of PTM|upregulation of posttranslational modification|activation of post-translational modification|upregulation of posttranslational protein modification|activation of post-translational amino acid modification|upregulation of posttranslational amino acid modification|activation of PTM|up-regulation of post-translational modification|positive regulation of post-translational amino acid modification|up-regulation of posttranslational modification|up-regulation of post-translational protein modification|up regulation of post-translational amino acid modification|up-regulation of PTM|up-regulation of posttranslational protein modification|up regulation of posttranslational amino acid modification|upregulation of post-translational modification|positive regulation of posttranslational amino acid modification|activation of posttranslational modification|upregulation of post-translational protein modification|activation of posttranslational protein modification|upregulation of PTM|upregulation of post-translational amino acid modification|activation of posttranslational amino acid modification|positive regulation of posttranslational modification http://purl.obolibrary.org/obo/GO_1901875 GO:1901876 biolink:BiologicalProcess regulation of calcium ion binding Any process that modulates the frequency, rate or extent of calcium ion binding. go-plus.json regulation of calcium ion storage activity http://purl.obolibrary.org/obo/GO_1901876 GO:1901873 biolink:BiologicalProcess regulation of post-translational protein modification Any process that modulates the frequency, rate or extent of post-translational protein modification. go-plus.json regulation of PTM|regulation of posttranslational modification|regulation of posttranslational protein modification|regulation of posttranslational amino acid modification|regulation of post-translational amino acid modification|regulation of post-translational modification http://purl.obolibrary.org/obo/GO_1901873 GO:0045389 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045389 GO:1901874 biolink:BiologicalProcess negative regulation of post-translational protein modification Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification. go-plus.json downregulation of post-translational modification|down regulation of PTM|inhibition of post-translational amino acid modification|downregulation of posttranslational modification|downregulation of post-translational protein modification|downregulation of PTM|downregulation of posttranslational protein modification|down regulation of posttranslational modification|inhibition of posttranslational amino acid modification|down-regulation of post-translational modification|negative regulation of post-translational modification|down regulation of posttranslational protein modification|down-regulation of post-translational protein modification|down-regulation of PTM|negative regulation of PTM|down-regulation of post-translational amino acid modification|negative regulation of post-translational amino acid modification|inhibition of posttranslational modification|down regulation of posttranslational amino acid modification|inhibition of posttranslational protein modification|inhibition of post-translational protein modification|downregulation of posttranslational amino acid modification|inhibition of post-translational modification|downregulation of post-translational amino acid modification|inhibition of PTM|down-regulation of posttranslational modification|negative regulation of posttranslational modification|down regulation of post-translational amino acid modification|down regulation of post-translational modification|negative regulation of posttranslational amino acid modification|down-regulation of posttranslational amino acid modification|negative regulation of posttranslational protein modification|down-regulation of posttranslational protein modification|down regulation of post-translational protein modification http://purl.obolibrary.org/obo/GO_1901874 GO:1901871 biolink:BiologicalProcess ecgonone methyl ester catabolic process The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester. go-plus.json ecgonone methyl ester breakdown|ecgonone methyl ester catabolism|ecgonone methyl ester degradation http://purl.obolibrary.org/obo/GO_1901871 GO:0045387 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045387 CHEBI:22450 biolink:ChemicalSubstance (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_22450 GO:1901872 biolink:BiologicalProcess ecgonone methyl ester biosynthetic process The chemical reactions and pathways resulting in the formation of ecgonone methyl ester. go-plus.json ecgonone methyl ester anabolism|ecgonone methyl ester synthesis|ecgonone methyl ester formation|ecgonone methyl ester biosynthesis http://purl.obolibrary.org/obo/GO_1901872 GO:0045388 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045388 GO:0045385 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045385 GO:1901870 biolink:BiologicalProcess ecgonone methyl ester metabolic process The chemical reactions and pathways involving ecgonone methyl ester. go-plus.json ecgonone methyl ester metabolism http://purl.obolibrary.org/obo/GO_1901870 GO:0045386 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045386 UBERON:0003660 biolink:AnatomicalEntity eyelid muscle A muscle that attaches to an eyelid. go-plus.json muscle organ of eyelid|blepharon muscle organ|muscle organ of blepharon|eyelid muscle organ http://purl.obolibrary.org/obo/UBERON_0003660 GO:0070329 biolink:BiologicalProcess tRNA seleno-modification The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule. go-plus.json tRNA base modification to selenouridine http://purl.obolibrary.org/obo/GO_0070329 GO:0070327 biolink:BiologicalProcess thyroid hormone transport The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json triiodothyronine transport|thyroxine transport http://purl.obolibrary.org/obo/GO_0070327 GO:0070328 biolink:BiologicalProcess triglyceride homeostasis Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell. go-plus.json triacylglycerol homeostasis http://purl.obolibrary.org/obo/GO_0070328 GO:0070325 biolink:MolecularActivity lipoprotein particle receptor binding Binding to a lipoprotein particle receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070325 GO:0070326 biolink:MolecularActivity very-low-density lipoprotein particle receptor binding Binding to a very-low-density lipoprotein receptor. go-plus.json apolipoprotein E receptor binding|very-low-density lipoprotein receptor binding|VLDL receptor binding|VLDLR binding http://purl.obolibrary.org/obo/GO_0070326 GO:0070323 biolink:BiologicalProcess obsolete positive regulation of translation in response to nitrogen starvation OBSOLETE. Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen. go-plus.json stimulation of translation in response to nitrogen starvation|up-regulation of translation in response to nitrogen starvation|activation of translation in response to nitrogen starvation|up regulation of translation in response to nitrogen starvation|upregulation of translation in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_0070323 UBERON:0003665 biolink:AnatomicalEntity post-anal tail muscle A muscle organ that attaches to a tail vertebra [Automatically generated definition]. go-plus.json tail muscle|muscle organ of post-vent region|muscle organ of tail|caudal muscle|tail muscle organ|post-vent region muscle organ http://purl.obolibrary.org/obo/UBERON_0003665 GO:0070324 biolink:MolecularActivity thyroid hormone binding Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland. go-plus.json triiodothyronine binding|thyroxine binding http://purl.obolibrary.org/obo/GO_0070324 goslim_chembl GO:0070321 biolink:BiologicalProcess obsolete regulation of translation in response to nitrogen starvation OBSOLETE. Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0070321 UBERON:0003663 biolink:AnatomicalEntity hindlimb muscle Any muscle organ that is part of a hindlimb [Automatically generated definition]. go-plus.json hindlimb muscle organ|muscle organ of hindlimb|muscle organ of inferior member|muscle organ of hind limb|muscle of posterior limb|free lower limb muscle|lower extremity muscle organ|muscle organ of lower extremity|muscle of free lower limb|lower limb skeletal muscle|hind limb muscle organ|inferior member muscle organ http://purl.obolibrary.org/obo/UBERON_0003663 UBERON:0003664 biolink:AnatomicalEntity manual digit muscle Any muscle organ that is part of a finger [Automatically generated definition]. go-plus.json muscle organ of digit of terminal segment of free upper limb|digitus manus muscle organ|digit of hand muscle organ|hand digit muscle|muscle organ of digit of hand|finger muscle organ|muscle organ of digitus manus|hand digit muscle|muscle organ of finger|muscle organ of terminal segment of free upper limb digit|fore limb digit muscle|digit of terminal segment of free upper limb muscle organ|terminal segment of free upper limb digit muscle organ|muscle organ of hand digit|hand digit muscle organ http://purl.obolibrary.org/obo/UBERON_0003664 GO:0070322 biolink:BiologicalProcess obsolete negative regulation of translation in response to nitrogen starvation OBSOLETE. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen. go-plus.json down-regulation of translation in response to nitrogen starvation|downregulation of translation in response to nitrogen starvation|down regulation of translation in response to nitrogen starvation|inhibition of translation in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_0070322 UBERON:0003661 biolink:AnatomicalEntity limb muscle Any muscle organ that is part of a limb [Automatically generated definition]. go-plus.json muscle organ of limb|limb muscle organ|limb skeletal muscle http://purl.obolibrary.org/obo/UBERON_0003661 UBERON:0003662 biolink:AnatomicalEntity forelimb muscle Any muscle organ that is part of a forelimb. go-plus.json musculature of the arm|arm muscle system|forelimb muscle organ|free upper limb muscle|fore limb muscle organ|wing muscle|muscle of free upper limb|muscle of upper limb|musculature of arm|upper limb skeletal muscle http://purl.obolibrary.org/obo/UBERON_0003662 GO:0070320 biolink:MolecularActivity inward rectifier potassium channel inhibitor activity Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0070320 GO:0070350 biolink:BiologicalProcess regulation of white fat cell proliferation Any process that modulates the frequency, rate or extent of white fat cell proliferation. go-plus.json regulation of white adipocyte proliferation|regulation of white adipose cell proliferation http://purl.obolibrary.org/obo/GO_0070350 GO:0045394 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045394 GO:0045395 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045395 GO:0070351 biolink:BiologicalProcess negative regulation of white fat cell proliferation Any process that stops or decreases the rate or extent of white fat cell proliferation. go-plus.json down-regulation of white fat cell proliferation|negative regulation of white adipose cell proliferation|downregulation of white fat cell proliferation|negative regulation of white adipocyte proliferation|down regulation of white fat cell proliferation|inhibition of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070351 GO:0045392 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045392 GO:0045393 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045393 GO:0045390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045390 GO:0045391 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045391 GO:1901888 biolink:BiologicalProcess regulation of cell junction assembly Any process that modulates the frequency, rate or extent of cell junction assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1901888 CHEBI:22423 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_22423 chebi_ph7_3 GO:1901889 biolink:BiologicalProcess negative regulation of cell junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. go-plus.json down regulation of cell junction assembly|inhibition of cell junction assembly|down-regulation of cell junction assembly|downregulation of cell junction assembly http://purl.obolibrary.org/obo/GO_1901889 GO:1901886 biolink:BiologicalProcess 2-hydroxybenzoyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA. go-plus.json 2-hydroxybenzoyl-CoA breakdown|2-hydroxybenzoyl-CoA degradation|2-hydroxybenzoyl-CoA catabolism http://purl.obolibrary.org/obo/GO_1901886 GO:1901887 biolink:BiologicalProcess 2-hydroxybenzoyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA. go-plus.json 2-hydroxybenzoyl-CoA biosynthesis|2-hydroxybenzoyl-CoA anabolism|2-hydroxybenzoyl-CoA synthesis|2-hydroxybenzoyl-CoA formation http://purl.obolibrary.org/obo/GO_1901887 GO:1901884 biolink:BiologicalProcess 4-hydroxycoumarin biosynthetic process The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin. go-plus.json 4-hydroxycoumarin synthesis|4-hydroxycoumarin formation|4-hydroxycoumarin biosynthesis|4-hydroxycoumarin anabolism http://purl.obolibrary.org/obo/GO_1901884 OBO:GOCHE_76815 biolink:OntologyClass substance with EC 2.7.7.* (nucleotidyltransferase) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76815 3_STAR GO:1901885 biolink:BiologicalProcess 2-hydroxybenzoyl-CoA metabolic process The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA. go-plus.json 2-hydroxybenzoyl-CoA metabolism http://purl.obolibrary.org/obo/GO_1901885 GO:1901882 biolink:BiologicalProcess 4-hydroxycoumarin metabolic process The chemical reactions and pathways involving 4-hydroxycoumarin. go-plus.json 4-hydroxycoumarin metabolism http://purl.obolibrary.org/obo/GO_1901882 GO:0045398 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045398 GO:0045399 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045399 GO:1901883 biolink:BiologicalProcess 4-hydroxycoumarin catabolic process The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin. go-plus.json 4-hydroxycoumarin catabolism|4-hydroxycoumarin degradation|4-hydroxycoumarin breakdown http://purl.obolibrary.org/obo/GO_1901883 GO:1901880 biolink:BiologicalProcess negative regulation of protein depolymerization Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization. go-plus.json inhibition of protein polymer catabolic process|inhibition of protein depolymerization|downregulation of protein polymer degradation|down regulation of protein polymer breakdown|downregulation of protein polymer breakdown|down regulation of protein polymer catabolic process|down-regulation of protein polymer catabolism|negative regulation of protein polymer catabolism|down-regulation of protein polymer degradation|negative regulation of protein polymer degradation|downregulation of protein polymer catabolic process|down-regulation of protein polymer breakdown|negative regulation of protein polymer breakdown|downregulation of protein polymer catabolism|down-regulation of protein depolymerization|negative regulation of protein polymer catabolic process|down-regulation of protein polymer catabolic process|down regulation of protein polymer catabolism|inhibition of protein polymer degradation|downregulation of protein depolymerization|inhibition of protein polymer catabolism|inhibition of protein polymer breakdown|down regulation of protein polymer degradation|down regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_1901880 GO:0045396 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045396 GO:1901881 biolink:BiologicalProcess positive regulation of protein depolymerization Any process that activates or increases the frequency, rate or extent of protein depolymerization. go-plus.json upregulation of protein polymer breakdown|up-regulation of protein polymer catabolism|upregulation of protein depolymerization|upregulation of protein polymer catabolic process|up regulation of protein polymer degradation|positive regulation of protein polymer degradation|activation of protein polymer catabolism|up regulation of protein polymer breakdown|up-regulation of protein depolymerization|activation of protein depolymerization|activation of protein polymer degradation|positive regulation of protein polymer catabolism|positive regulation of protein polymer breakdown|up regulation of protein polymer catabolic process|up regulation of protein polymer catabolism|positive regulation of protein polymer catabolic process|activation of protein polymer breakdown|up-regulation of protein polymer degradation|activation of protein polymer catabolic process|up-regulation of protein polymer breakdown|up regulation of protein depolymerization|upregulation of protein polymer catabolism|up-regulation of protein polymer catabolic process|upregulation of protein polymer degradation http://purl.obolibrary.org/obo/GO_1901881 GO:0045397 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045397 GO:1901890 biolink:BiologicalProcess positive regulation of cell junction assembly Any process that activates or increases the frequency, rate or extent of cell junction assembly. go-plus.json up regulation of cell junction assembly|upregulation of cell junction assembly|up-regulation of cell junction assembly|activation of cell junction assembly http://purl.obolibrary.org/obo/GO_1901890 GO:0070358 biolink:BiologicalProcess actin polymerization-dependent cell motility A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell. go-plus.json cell motility by actin tail formation http://purl.obolibrary.org/obo/GO_0070358 GO:0070359 biolink:BiologicalProcess actin polymerization-dependent cell motility involved in migration of symbiont in host A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell. go-plus.json actin polymerization-dependent cell motility involved in migration of symbiont within host http://purl.obolibrary.org/obo/GO_0070359 GO:0070356 biolink:CellularComponent synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof). go-plus.json STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2 complex|SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2) http://purl.obolibrary.org/obo/GO_0070356 GO:0070357 biolink:CellularComponent alphav-beta3 integrin-CD47 complex A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP). go-plus.json ITGB3-ITGAV-CD47 complex http://purl.obolibrary.org/obo/GO_0070357 GO:0070354 biolink:CellularComponent GATA2-TAL1-TCF3-Lmo2 complex A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis. go-plus.json http://purl.obolibrary.org/obo/GO_0070354 GO:0070355 biolink:CellularComponent synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof). go-plus.json STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2-CPLX2 complex|SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2, CPLX2) http://purl.obolibrary.org/obo/GO_0070355 GO:0070352 biolink:BiologicalProcess positive regulation of white fat cell proliferation Any process that activates or increases the rate or extent of white fat cell proliferation. go-plus.json stimulation of white fat cell proliferation|up-regulation of white fat cell proliferation|activation of white fat cell proliferation|positive regulation of white adipose cell proliferation|up regulation of white fat cell proliferation|positive regulation of white adipocyte proliferation|upregulation of white fat cell proliferation http://purl.obolibrary.org/obo/GO_0070352 GO:0070353 biolink:CellularComponent GATA1-TAL1-TCF3-Lmo2 complex A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis. go-plus.json http://purl.obolibrary.org/obo/GO_0070353 GO:0070340 biolink:BiologicalProcess detection of bacterial lipopeptide The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0070340 GO:1901899 biolink:BiologicalProcess positive regulation of relaxation of cardiac muscle Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle. go-plus.json upregulation of relaxation of cardiac muscle|up-regulation of relaxation of cardiac muscle|activation of relaxation of cardiac muscle|up regulation of relaxation of cardiac muscle http://purl.obolibrary.org/obo/GO_1901899 GO:1901897 biolink:BiologicalProcess regulation of relaxation of cardiac muscle Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle. go-plus.json http://purl.obolibrary.org/obo/GO_1901897 GO:1901898 biolink:BiologicalProcess negative regulation of relaxation of cardiac muscle Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle. go-plus.json down regulation of relaxation of cardiac muscle|inhibition of relaxation of cardiac muscle|down-regulation of relaxation of cardiac muscle|downregulation of relaxation of cardiac muscle http://purl.obolibrary.org/obo/GO_1901898 GO:1901895 biolink:BiologicalProcess negative regulation of ATPase-coupled calcium transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity. go-plus.json downregulation of calcium ABC transporter|downregulation of calcium-translocating P-type ATPase activity|downregulation of sarcoplasmic reticulum ATPase|inhibition of calcium efflux ATPase|downregulation of Ca2+-transporting ATPase activity|down regulation of ATP phosphohydrolase (Ca2+-transporting)|downregulation of Ca2+-pumping ATPase activity|inhibition of plasma membrane Ca-ATPase|down-regulation of calcium-transporting ATPase activity|inhibition of calcium transporting ATPase activity|down regulation of calcium-translocating P-type ATPase activity|negative regulation of calcium pump|inhibition of Ca(2+)-transporting ATPase activity|down-regulation of calcium pump|down regulation of Ca2+-pumping ATPase activity|downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down regulation of calcium efflux ATPase|negative regulation of calcium ABC transporter|inhibition of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of calcium ABC transporter|down-regulation of sarcoplasmic reticulum ATPase|negative regulation of sarcoplasmic reticulum ATPase|negative regulation of Ca2+-transporting ATPase activity|down-regulation of Ca2+-transporting ATPase activity|down regulation of plasma membrane Ca-ATPase|inhibition of calcium-translocating P-type ATPase activity|downregulation of calcium efflux ATPase|down regulation of Ca(2+)-transporting ATPase activity|downregulation of calcium-transporting ATPase activity|down regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|inhibition of Ca2+-pumping ATPase activity|downregulation of calcium pump|downregulation of plasma membrane Ca-ATPase|negative regulation of calcium transporting ATPase activity|down-regulation of calcium transporting ATPase activity|downregulation of Ca(2+)-transporting ATPase activity|down regulation of calcium-transporting ATPase activity|down regulation of calcium pump|inhibition of calcium-transporting ATPase activity|inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase|negative regulation of calcium-transporting ATPase activity|down-regulation of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of calcium efflux ATPase|inhibition of calcium ABC transporter|negative regulation of ATP phosphohydrolase (Ca2+-transporting)|negative regulation of calcium efflux ATPase|inhibition of Ca2+-transporting ATPase activity|inhibition of sarcoplasmic reticulum ATPase|negative regulation of calcium-translocating P-type ATPase activity|negative regulation of plasma membrane Ca-ATPase|down-regulation of calcium-translocating P-type ATPase activity|down-regulation of plasma membrane Ca-ATPase|down-regulation of Ca(2+)-transporting ATPase activity|downregulation of calcium transporting ATPase activity|negative regulation of Ca2+-pumping ATPase activity|negative regulation of Ca(2+)-transporting ATPase activity|down-regulation of Ca2+-pumping ATPase activity|inhibition of calcium pump|down regulation of calcium ABC transporter|down regulation of sarcoplasmic reticulum ATPase|down regulation of Ca2+-transporting ATPase activity|down regulation of calcium transporting ATPase activity|downregulation of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|negative regulation of sarco(endo)plasmic reticulum Ca2+-ATPase http://purl.obolibrary.org/obo/GO_1901895 GO:1901896 biolink:BiologicalProcess positive regulation of ATPase-coupled calcium transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity. go-plus.json up regulation of Ca2+-pumping ATPase activity|upregulation of calcium transporting ATPase activity|up-regulation of Ca(2+)-transporting ATPase activity|up regulation of calcium ABC transporter|positive regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up regulation of sarcoplasmic reticulum ATPase|positive regulation of calcium ABC transporter|up regulation of Ca2+-transporting ATPase activity|upregulation of calcium efflux ATPase|up regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|activation of calcium pump|upregulation of ATP phosphohydrolase (Ca2+-transporting)|positive regulation of sarcoplasmic reticulum ATPase|upregulation of calcium-translocating P-type ATPase activity|positive regulation of Ca2+-transporting ATPase activity|upregulation of plasma membrane Ca-ATPase|upregulation of Ca2+-pumping ATPase activity|activation of calcium ABC transporter|up-regulation of calcium transporting ATPase activity|upregulation of Ca(2+)-transporting ATPase activity|up regulation of calcium-transporting ATPase activity|positive regulation of calcium pump|activation of sarcoplasmic reticulum ATPase|up regulation of calcium pump|activation of Ca2+-transporting ATPase activity|upregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of ATP phosphohydrolase (Ca2+-transporting)|up regulation of calcium efflux ATPase|up-regulation of calcium ABC transporter|activation of calcium transporting ATPase activity|up-regulation of calcium-translocating P-type ATPase activity|up-regulation of sarcoplasmic reticulum ATPase|up regulation of plasma membrane Ca-ATPase|positive regulation of calcium efflux ATPase|up-regulation of Ca2+-transporting ATPase activity|positive regulation of plasma membrane Ca-ATPase|up-regulation of Ca2+-pumping ATPase activity|upregulation of calcium-transporting ATPase activity|up regulation of Ca(2+)-transporting ATPase activity|activation of ATP phosphohydrolase (Ca2+-transporting)|positive regulation of calcium transporting ATPase activity|activation of calcium efflux ATPase|activation of calcium-translocating P-type ATPase activity|positive regulation of Ca(2+)-transporting ATPase activity|upregulation of calcium pump|up regulation of calcium transporting ATPase activity|up-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|activation of plasma membrane Ca-ATPase|activation of Ca2+-pumping ATPase activity|upregulation of calcium ABC transporter|positive regulation of calcium-transporting ATPase activity|upregulation of sarcoplasmic reticulum ATPase|positive regulation of ATP phosphohydrolase (Ca2+-transporting)|activation of Ca(2+)-transporting ATPase activity|upregulation of Ca2+-transporting ATPase activity|positive regulation of calcium-translocating P-type ATPase activity|up-regulation of calcium efflux ATPase|up regulation of ATP phosphohydrolase (Ca2+-transporting)|activation of calcium-transporting ATPase activity|up-regulation of calcium-transporting ATPase activity|up regulation of calcium-translocating P-type ATPase activity|activation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of plasma membrane Ca-ATPase|positive regulation of Ca2+-pumping ATPase activity|up-regulation of calcium pump http://purl.obolibrary.org/obo/GO_1901896 GO:1901893 biolink:BiologicalProcess positive regulation of cell septum assembly Any process that activates or increases the frequency, rate or extent of cell septum assembly. go-plus.json up regulation of cell septum assembly|upregulation of cell septum assembly|up-regulation of cell septum assembly|activation of cell septum assembly http://purl.obolibrary.org/obo/GO_1901893 GO:1901894 biolink:BiologicalProcess regulation of ATPase-coupled calcium transmembrane transporter activity Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity. go-plus.json regulation of ATP phosphohydrolase (Ca2+-transporting)|regulation of calcium-translocating P-type ATPase activity|regulation of Ca2+-pumping ATPase activity|regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|regulation of calcium efflux ATPase|regulation of plasma membrane Ca-ATPase|regulation of Ca(2+)-transporting ATPase activity|regulation of calcium pump|regulation of calcium transporting ATPase activity|regulation of calcium ABC transporter|regulation of sarcoplasmic reticulum ATPase|regulation of calcium-transporting ATPase activity|regulation of Ca2+-transporting ATPase activity http://purl.obolibrary.org/obo/GO_1901894 GO:1901891 biolink:BiologicalProcess regulation of cell septum assembly Any process that modulates the frequency, rate or extent of cell septum assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1901891 GO:1901892 biolink:BiologicalProcess negative regulation of cell septum assembly Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly. go-plus.json downregulation of cell septum assembly|down regulation of cell septum assembly|inhibition of cell septum assembly|down-regulation of cell septum assembly http://purl.obolibrary.org/obo/GO_1901892 GO:0070349 biolink:BiologicalProcess positive regulation of brown fat cell proliferation Any process that activates or increases the rate or extent of brown fat cell proliferation. go-plus.json stimulation of brown fat cell proliferation|up-regulation of brown fat cell proliferation|activation of brown fat cell proliferation|positive regulation of brown adipose cell proliferation|up regulation of brown fat cell proliferation|positive regulation of brown adipocyte proliferation|upregulation of brown fat cell proliferation http://purl.obolibrary.org/obo/GO_0070349 GO:0070347 biolink:BiologicalProcess regulation of brown fat cell proliferation Any process that modulates the frequency, rate or extent of brown fat cell proliferation. go-plus.json regulation of brown adipocyte proliferation|regulation of brown adipose cell proliferation http://purl.obolibrary.org/obo/GO_0070347 GO:0070348 biolink:BiologicalProcess negative regulation of brown fat cell proliferation Any process that stops or decreases the rate or extent of brown fat cell proliferation. go-plus.json down-regulation of brown fat cell proliferation|negative regulation of brown adipose cell proliferation|downregulation of brown fat cell proliferation|down regulation of brown fat cell proliferation|inhibition of brown fat cell proliferation|negative regulation of brown adipocyte proliferation http://purl.obolibrary.org/obo/GO_0070348 GO:0070345 biolink:BiologicalProcess negative regulation of fat cell proliferation Any process that stops or decreases the rate or extent of fat cell proliferation. go-plus.json downregulation of fat cell proliferation|down regulation of fat cell proliferation|inhibition of fat cell proliferation|negative regulation of adipocyte proliferation|down-regulation of fat cell proliferation|negative regulation of adipose cell proliferation http://purl.obolibrary.org/obo/GO_0070345 GO:0070346 biolink:BiologicalProcess positive regulation of fat cell proliferation Any process that activates or increases the rate or extent of fat cell proliferation. go-plus.json upregulation of fat cell proliferation|stimulation of fat cell proliferation|positive regulation of adipocyte proliferation|up-regulation of fat cell proliferation|activation of fat cell proliferation|positive regulation of adipose cell proliferation|up regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070346 GO:0070343 biolink:BiologicalProcess white fat cell proliferation The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population. go-plus.json white adipocyte proliferation|white adipose cell proliferation http://purl.obolibrary.org/obo/GO_0070343 GO:0070344 biolink:BiologicalProcess regulation of fat cell proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. go-plus.json regulation of adipose cell proliferation|regulation of adipocyte proliferation http://purl.obolibrary.org/obo/GO_0070344 GO:0070341 biolink:BiologicalProcess fat cell proliferation The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. go-plus.json adipocyte proliferation|adipose cell proliferation http://purl.obolibrary.org/obo/GO_0070341 GO:0070342 biolink:BiologicalProcess brown fat cell proliferation The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species. go-plus.json brown adipose cell proliferation|brown adipocyte proliferation http://purl.obolibrary.org/obo/GO_0070342 GO:0070372 biolink:BiologicalProcess regulation of ERK1 and ERK2 cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. go-plus.json regulation of ERK2 cascade|regulation of ERK1 cascade|regulation of ERK1 and ERK2 signalling pathway|regulation of ERK1/2 cascade|regulation of ERK cascade|regulation of MAPK3 cascade|regulation of ERK1 and ERK2 signaling pathway|regulation of MAPK1 cascade http://purl.obolibrary.org/obo/GO_0070372 GO:0070373 biolink:BiologicalProcess negative regulation of ERK1 and ERK2 cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. go-plus.json negative regulation of MAPK3 cascade|negative regulation of MAPK1 cascade|negative regulation of ERK1 and ERK2 signaling pathway|down regulation of ERK1 and ERK2 cascade|downregulation of ERK1 and ERK2 cascade|down-regulation of ERK1 and ERK2 cascade|negative regulation of ERK2 cascade|negative regulation of ERK1 cascade|negative regulation of ERK cascade|negative regulation of ERK1 and ERK2 signalling pathway|negative regulation of ERK1/2 cascade|inhibition of ERK1 and ERK2 cascade http://purl.obolibrary.org/obo/GO_0070373 GO:0070370 biolink:BiologicalProcess cellular heat acclimation Any process that increases heat tolerance of a cell in response to high temperatures. go-plus.json cellular thermotolerance http://purl.obolibrary.org/obo/GO_0070370 GO:0070371 biolink:BiologicalProcess ERK1 and ERK2 cascade An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. go-plus.json MAPK3 cascade|MAPK1 cascade|ERK1 and ERK2 signaling pathway|extracellular signal-regulated kinase 1/2 cascade|ERK2 cascade|ERK1 cascade|ERK1 and ERK2 signalling pathway|extracellular signal-regulated kinase 1/2 (ERK1/2) cascade|ERK1/2 cascade|ERK cascade http://purl.obolibrary.org/obo/GO_0070371 GO:0070378 biolink:BiologicalProcess positive regulation of ERK5 cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. go-plus.json positive regulation of MAPK7 cascade|positive regulation of BMK cascade|positive regulation of BMK1 cascade|up-regulation of BMK cascade|positive regulation of BMK signaling pathway|upregulation of BMK cascade|positive regulation of BMK signalling pathway|positive regulation of ERK5 signaling pathway|up regulation of BMK cascade|activation of BMK cascade|stimulation of BMK cascade http://purl.obolibrary.org/obo/GO_0070378 GO:0070379 biolink:MolecularActivity high mobility group box 1 binding Binding to high mobility group box 1 (HMBGB1). go-plus.json HMGB1 binding http://purl.obolibrary.org/obo/GO_0070379 GO:0070376 biolink:BiologicalProcess regulation of ERK5 cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. go-plus.json regulation of BMK signaling pathway|regulation of BMK1 cascade|regulation of MAPK7 cascade|regulation of BMK cascade|regulation of ERK5 signaling pathway|regulation of BMK signalling pathway http://purl.obolibrary.org/obo/GO_0070376 GO:0070377 biolink:BiologicalProcess negative regulation of ERK5 cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. go-plus.json negative regulation of MAPK7 cascade|negative regulation of BMK cascade|inhibition of BMK cascade|negative regulation of BMK signaling pathway|negative regulation of ERK5 signaling pathway|negative regulation of BMK signalling pathway|down regulation of BMK cascade|downregulation of BMK cascade|down-regulation of BMK cascade|negative regulation of BMK1 cascade http://purl.obolibrary.org/obo/GO_0070377 GO:0070374 biolink:BiologicalProcess positive regulation of ERK1 and ERK2 cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. go-plus.json positive regulation of MAPK1 cascade|positive regulation of ERK1 and ERK2 signaling pathway|upregulation of ERK1 and ERK2 cascade|up regulation of ERK1 and ERK2 cascade|activation of ERK1 and ERK2 cascade|stimulation of ERK1 and ERK2 cascade|positive regulation of ERK cascade|positive regulation of ERK2 cascade|positive regulation of ERK1 cascade|up-regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 signalling pathway|positive regulation of ERK1/2 cascade|positive regulation of MAPK3 cascade http://purl.obolibrary.org/obo/GO_0070374 GO:0070375 biolink:BiologicalProcess ERK5 cascade An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. go-plus.json MAPK7 cascade|big MAP kinase signaling cascade|BMK cascade|ERK5 signaling pathway|BMK signalling pathway|extracellular signal-regulated kinase 5 cascade|BMK signaling pathway|BMK1 cascade http://purl.obolibrary.org/obo/GO_0070375 GO:0070361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070361 GO:0070362 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070362 GO:0070360 biolink:BiologicalProcess migration of symbiont within host by polymerization of host actin The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0070360 GO:0070369 biolink:CellularComponent beta-catenin-TCF7L2 complex A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. go-plus.json beta-catenin-TCF4 complex http://purl.obolibrary.org/obo/GO_0070369 GO:0070367 biolink:BiologicalProcess negative regulation of hepatocyte differentiation Any process that stops or decreases the rate or extent of hepatocyte differentiation. go-plus.json down regulation of hepatocyte differentiation|inhibition of hepatocyte differentiation|negative regulation of liver cell differentiation|down-regulation of hepatocyte differentiation|downregulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070367 GO:0070368 biolink:BiologicalProcess positive regulation of hepatocyte differentiation Any process that activates or increases the rate or extent of hepatocyte differentiation. go-plus.json upregulation of hepatocyte differentiation|stimulation of hepatocyte differentiation|up-regulation of hepatocyte differentiation|activation of hepatocyte differentiation|positive regulation of liver cell differentiation|up regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070368 GO:0070365 biolink:BiologicalProcess hepatocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. go-plus.json liver cell differentiation http://purl.obolibrary.org/obo/GO_0070365 GO:0070366 biolink:BiologicalProcess regulation of hepatocyte differentiation Any process that modulates the frequency, rate or extent of hepatocyte differentiation. go-plus.json regulation of liver cell differentiation http://purl.obolibrary.org/obo/GO_0070366 GO:0070363 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070363 GO:0070364 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070364 CHEBI:46398 biolink:ChemicalSubstance UTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_46398 chebi_ph7_3 CHEBI:71354 biolink:ChemicalSubstance norsolorinic acid anthrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71354 CHEBI:71355 biolink:ChemicalSubstance beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_71355 chebi_ph7_3 CHEBI:71356 biolink:ChemicalSubstance norsolorinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71356 GO:0021540 biolink:BiologicalProcess corpus callosum morphogenesis The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. go-plus.json http://purl.obolibrary.org/obo/GO_0021540 GO:0021541 biolink:BiologicalProcess ammon gyrus development The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons. go-plus.json cornu ammonis development|Ammon's horn development http://purl.obolibrary.org/obo/GO_0021541 CHEBI:71358 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alaninate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71358 chebi_ph7_3 GO:0021542 biolink:BiologicalProcess dentate gyrus development The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. go-plus.json http://purl.obolibrary.org/obo/GO_0021542 GO:0021543 biolink:BiologicalProcess pallium development The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0021543 GO:0021544 biolink:BiologicalProcess subpallium development The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0021544 GO:0045512 biolink:MolecularActivity interleukin-26 binding Binding to interleukin-26. go-plus.json IL-26 binding http://purl.obolibrary.org/obo/GO_0045512 GO:0045513 biolink:MolecularActivity interleukin-27 binding Binding to interleukin-27. go-plus.json IL-27 binding http://purl.obolibrary.org/obo/GO_0045513 GO:0045510 biolink:MolecularActivity interleukin-24 binding Binding to interleukin-24. go-plus.json IL-24 binding http://purl.obolibrary.org/obo/GO_0045510 GO:0045511 biolink:MolecularActivity interleukin-25 binding Binding to interleukin-25. go-plus.json IL-25 binding http://purl.obolibrary.org/obo/GO_0045511 GO:0045518 biolink:MolecularActivity interleukin-22 receptor binding Binding to an interleukin-22 receptor. go-plus.json interleukin-22 receptor ligand|IL-22 http://purl.obolibrary.org/obo/GO_0045518 GO:0045519 biolink:MolecularActivity interleukin-23 receptor binding Binding to an interleukin-23 receptor. go-plus.json interleukin-23 receptor ligand|IL-23 http://purl.obolibrary.org/obo/GO_0045519 GO:0045516 biolink:MolecularActivity interleukin-19 receptor binding Binding to an interleukin-19 receptor. go-plus.json interleukin-19 receptor ligand|IL-19 http://purl.obolibrary.org/obo/GO_0045516 GO:0045517 biolink:MolecularActivity interleukin-20 receptor binding Binding to an interleukin-20 receptor. go-plus.json interleukin-20 receptor ligand|IL-20 http://purl.obolibrary.org/obo/GO_0045517 GO:0045514 biolink:MolecularActivity interleukin-16 receptor binding Binding to an interleukin-16 receptor. go-plus.json interleukin-16 receptor ligand|IL-16 http://purl.obolibrary.org/obo/GO_0045514 GO:0045515 biolink:MolecularActivity interleukin-18 receptor binding Binding to an interleukin-18 receptor. go-plus.json interleukin-18 receptor ligand|IL-18 http://purl.obolibrary.org/obo/GO_0045515 GO:0021545 biolink:BiologicalProcess cranial nerve development The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. go-plus.json http://purl.obolibrary.org/obo/GO_0021545 GO:0021546 biolink:BiologicalProcess rhombomere development The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. go-plus.json http://purl.obolibrary.org/obo/GO_0021546 GO:0021547 biolink:BiologicalProcess midbrain-hindbrain boundary initiation The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json MHB biosynthesis|midbrain-hindbrain boundary biosynthesis|midbrain-hindbrain boundary formation|isthmus biosynthesis|isthmus formation|MHB formation http://purl.obolibrary.org/obo/GO_0021547 GO:0021548 biolink:BiologicalProcess pons development The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. go-plus.json http://purl.obolibrary.org/obo/GO_0021548 GO:0021549 biolink:BiologicalProcess cerebellum development The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. go-plus.json http://purl.obolibrary.org/obo/GO_0021549 CHEBI:71352 biolink:ChemicalSubstance L-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_71352 CHEBI:71353 biolink:ChemicalSubstance Mo(VI)-molybdopterin cytosine dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71353 CHEBI:71365 biolink:ChemicalSubstance rifampicin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71365 chebi_ph7_3 GO:0021530 biolink:BiologicalProcess spinal cord oligodendrocyte cell fate specification The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0021530 GO:0021531 biolink:BiologicalProcess spinal cord radial glial cell differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json radial glial cell differentiation in spinal cord http://purl.obolibrary.org/obo/GO_0021531 GO:0021532 biolink:BiologicalProcess neural tube patterning The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0021532 GO:0021533 biolink:BiologicalProcess cell differentiation in hindbrain The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021533 GO:0045523 biolink:MolecularActivity interleukin-27 receptor binding Binding to an interleukin-27 receptor. go-plus.json interleukin-27 receptor ligand|IL-27 http://purl.obolibrary.org/obo/GO_0045523 GO:0045524 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045524 GO:0045521 biolink:MolecularActivity interleukin-25 receptor binding Binding to an interleukin-25 receptor. go-plus.json interleukin-25 receptor ligand|IL-25 http://purl.obolibrary.org/obo/GO_0045521 GO:0045522 biolink:MolecularActivity interleukin-26 receptor binding Binding to an interleukin-26 receptor. go-plus.json interleukin-26 receptor ligand|IL-26 http://purl.obolibrary.org/obo/GO_0045522 GO:0045520 biolink:MolecularActivity interleukin-24 receptor binding Binding to an interleukin-24 receptor. go-plus.json interleukin-24 receptor ligand|IL-24 http://purl.obolibrary.org/obo/GO_0045520 GO:0045529 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045529 GO:0045527 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045527 GO:0045528 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045528 GO:0045525 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045525 GO:0045526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045526 GO:0021534 biolink:BiologicalProcess cell proliferation in hindbrain The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021534 GO:0021535 biolink:BiologicalProcess cell migration in hindbrain The orderly movement of a cell that will reside in the hindbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0021535 GO:0021536 biolink:BiologicalProcess diencephalon development The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0021536 GO:0021537 biolink:BiologicalProcess telencephalon development The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. go-plus.json cerebrum development http://purl.obolibrary.org/obo/GO_0021537 CHEBI:71361 biolink:ChemicalSubstance 8-oxo-dAMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71361 chebi_ph7_3 GO:0021538 biolink:BiologicalProcess epithalamus development The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0021538 CHEBI:71362 biolink:ChemicalSubstance 8-oxo-dADP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71362 chebi_ph7_3 GO:0021539 biolink:BiologicalProcess subthalamus development The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis. go-plus.json ventral thalamus development http://purl.obolibrary.org/obo/GO_0021539 CHEBI:71363 biolink:ChemicalSubstance 2-oxo-dADP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71363 chebi_ph7_3 GO:0021520 biolink:BiologicalProcess spinal cord motor neuron cell fate specification The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0021520 GO:0021521 biolink:BiologicalProcess ventral spinal cord interneuron specification The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0021521 GO:0021522 biolink:BiologicalProcess spinal cord motor neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021522 GO:0045534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045534 GO:0045535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045535 GO:0045532 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045532 GO:0045533 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045533 GO:0045530 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045530 GO:0045531 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045531 GO:0045538 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045538 GO:0045539 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045539 GO:0045536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045536 GO:0045537 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045537 GO:0021523 biolink:BiologicalProcess somatic motor neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021523 GO:0021524 biolink:BiologicalProcess visceral motor neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021524 GO:0021525 biolink:BiologicalProcess lateral motor column neuron differentiation The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021525 GO:0021526 biolink:BiologicalProcess medial motor column neuron differentiation The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021526 GO:0021527 biolink:BiologicalProcess spinal cord association neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json spinal cord dorsal interneuron differentiation http://purl.obolibrary.org/obo/GO_0021527 GO:0021528 biolink:BiologicalProcess commissural neuron differentiation in spinal cord The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021528 GO:0021529 biolink:BiologicalProcess spinal cord oligodendrocyte cell differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021529 GO:0021510 biolink:BiologicalProcess spinal cord development The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0021510 GO:0021511 biolink:BiologicalProcess spinal cord patterning The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021511 GO:0045545 biolink:MolecularActivity syndecan binding Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0045545 GO:0045546 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045546 GO:0045543 biolink:MolecularActivity gibberellin 2-beta-dioxygenase activity Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2. RHEA:15005|MetaCyc:PWY-102|EC:1.14.11.13 go-plus.json (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|gibberellin 2-beta-hydroxylase activity|gibberellin 2beta-dioxygenase activity|gibberellin 2-oxidase activity|gibberellin 2beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0045543 GO:0045544 biolink:MolecularActivity gibberellin 20-oxidase activity Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones. go-plus.json http://purl.obolibrary.org/obo/GO_0045544 GO:0045541 biolink:BiologicalProcess negative regulation of cholesterol biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. go-plus.json negative regulation of cholesterol anabolism|negative regulation of cholesterol synthesis|negative regulation of cholesterol formation|negative regulation of cholesterol biosynthesis|down-regulation of cholesterol biosynthetic process|downregulation of cholesterol biosynthetic process|down regulation of cholesterol biosynthetic process|inhibition of cholesterol biosynthetic process http://purl.obolibrary.org/obo/GO_0045541 GO:0045542 biolink:BiologicalProcess positive regulation of cholesterol biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. go-plus.json positive regulation of cholesterol synthesis|stimulation of cholesterol biosynthetic process|positive regulation of cholesterol formation|up-regulation of cholesterol biosynthetic process|activation of cholesterol biosynthetic process|positive regulation of cholesterol biosynthesis|up regulation of cholesterol biosynthetic process|upregulation of cholesterol biosynthetic process|positive regulation of cholesterol anabolism http://purl.obolibrary.org/obo/GO_0045542 GO:0045540 biolink:BiologicalProcess regulation of cholesterol biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. go-plus.json regulation of cholesterol anabolism|regulation of cholesterol biosynthesis|regulation of cholesterol synthesis|regulation of cholesterol formation http://purl.obolibrary.org/obo/GO_0045540 GO:0045549 biolink:MolecularActivity 9-cis-epoxycarotenoid dioxygenase activity Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al. EC:1.13.11.51 go-plus.json PvNCED1|NCED|nine-cis-epoxycarotenoid dioxygenase activity|AtNCED3|9-cis-epoxycarotenoid 11,12-dioxygenase activity|VP14|neoxanthin cleavage enzyme http://purl.obolibrary.org/obo/GO_0045549 GO:0045547 biolink:MolecularActivity dehydrodolichyl diphosphate synthase activity Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0045547 GO:0045548 biolink:MolecularActivity phenylalanine ammonia-lyase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate. RHEA:21384|EC:4.3.1.25|EC:4.3.1.24 go-plus.json phe ammonia-lyase activity|PAL activity|L-phenylalanine ammonia-lyase activity|phenylalanine ammonium-lyase activity|phenylalanine deaminase activity http://purl.obolibrary.org/obo/GO_0045548 GO:0021512 biolink:BiologicalProcess spinal cord anterior/posterior patterning The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord. go-plus.json spinal cord rostrocaudal patterning|spinal cord anterior-posterior patterning http://purl.obolibrary.org/obo/GO_0021512 GO:0021513 biolink:BiologicalProcess spinal cord dorsal/ventral patterning The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord. go-plus.json spinal cord dorsoventral patterning|spinal cord dorsal-ventral patterning http://purl.obolibrary.org/obo/GO_0021513 GO:0021514 biolink:BiologicalProcess ventral spinal cord interneuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021514 GO:0021515 biolink:BiologicalProcess cell differentiation in spinal cord The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0021515 GO:0021516 biolink:BiologicalProcess dorsal spinal cord development The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. go-plus.json http://purl.obolibrary.org/obo/GO_0021516 GO:0021517 biolink:BiologicalProcess ventral spinal cord development The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. go-plus.json http://purl.obolibrary.org/obo/GO_0021517 GO:0021518 biolink:BiologicalProcess spinal cord commissural neuron specification The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0021518 GO:0021519 biolink:BiologicalProcess spinal cord association neuron specification The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0021519 CHEBI:71399 biolink:ChemicalSubstance (beta-L-Ara4N)2-(KDO)2-lipid A(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71399 chebi_ph7_3 CHEBI:22385 biolink:ChemicalSubstance alpha-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_22385 GO:0045556 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045556 GO:0045557 biolink:BiologicalProcess obsolete TRAIL receptor biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. go-plus.json TRAIL receptor biosynthesis|TRAIL receptor anabolism|TRAIL receptor synthesis|TRAIL receptor formation http://purl.obolibrary.org/obo/GO_0045557 GO:0045554 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045554 GO:0045555 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045555 GO:0045552 biolink:MolecularActivity dihydrokaempferol 4-reductase activity Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+. RHEA:23016|MetaCyc:DIHYDROKAEMPFEROL-4-REDUCTASE-RXN|EC:1.1.1.219 go-plus.json cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity|dihydromyricetin reductase activity|dihydroflavonol 4-reductase activity|NADPH-dihydromyricetin reductase activity|dihydroflavanol 4-reductase activity|dihydroquercetin reductase activity http://purl.obolibrary.org/obo/GO_0045552 GO:0045553 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045553 GO:0045550 biolink:MolecularActivity geranylgeranyl reductase activity Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0045550 GO:0045551 biolink:MolecularActivity cinnamyl-alcohol dehydrogenase activity Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+. RHEA:10392|EC:1.1.1.195|MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN go-plus.json CAD activity|cinnamyl-alcohol:NADP+ oxidoreductase activity|cinnamyl alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0045551 GO:0021509 biolink:BiologicalProcess roof plate formation The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021509 GO:0070518 biolink:CellularComponent alpha4-beta1 integrin-CD53 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family. go-plus.json ITGA4-ITGB1-CD53 complex http://purl.obolibrary.org/obo/GO_0070518 GO:0070519 biolink:CellularComponent alpha4-beta1 integrin-CD63 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family. go-plus.json ITGA4-ITGB1-CD63 complex http://purl.obolibrary.org/obo/GO_0070519 GO:0070516 biolink:CellularComponent CAK-ERCC2 complex A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2. go-plus.json cyclin-dependent protein kinase activating kinase holoenzyme-ERCC2 complex http://purl.obolibrary.org/obo/GO_0070516 GO:0070517 biolink:CellularComponent DNA replication factor C core complex A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37. go-plus.json RFC core complex http://purl.obolibrary.org/obo/GO_0070517 GO:0045558 biolink:BiologicalProcess obsolete TRAIL receptor 1 biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R1 (TNF-related apoptosis inducing ligand receptor 1), which engages a caspase-dependent apoptotic pathway. go-plus.json TRAIL receptor 1 synthesis|TRAIL receptor 1 formation|tumor necrosis factor receptor superfamily member 10A biosynthetic process|TRAIL receptor 1 biosynthesis|TRAIL receptor 1 anabolism http://purl.obolibrary.org/obo/GO_0045558 GO:0070514 biolink:CellularComponent SRF-myogenin-E12 complex A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes. go-plus.json http://purl.obolibrary.org/obo/GO_0070514 GO:0070515 biolink:CellularComponent alphaIIb-beta3 integrin-talin complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin. go-plus.json ITGA2b-ITGB3-TLN1 complex http://purl.obolibrary.org/obo/GO_0070515 GO:0045559 biolink:BiologicalProcess obsolete TRAIL receptor 2 biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R2 (TNF-related apoptosis inducing ligand receptor 2), which engages a caspase-dependent apoptotic pathway and mediates apoptosis via the intracellular adaptor molecule FADD/MORT1. go-plus.json TRAIL receptor 2 synthesis|TRAIL receptor 2 formation|tumor necrosis factor receptor superfamily member 10B biosynthetic process|TRAIL receptor 2 biosynthesis|TRAIL receptor 2 anabolism http://purl.obolibrary.org/obo/GO_0045559 GO:0070512 biolink:BiologicalProcess positive regulation of histone H4-K20 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. go-plus.json upregulation of histone H4-K20 methylation|stimulation of histone H4-K20 methylation|up-regulation of histone H4-K20 methylation|activation of histone H4-K20 methylation|up regulation of histone H4-K20 methylation http://purl.obolibrary.org/obo/GO_0070512 GO:0021501 biolink:BiologicalProcess prechordal plate formation The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021501 GO:0070513 biolink:MolecularActivity death domain binding Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. go-plus.json http://purl.obolibrary.org/obo/GO_0070513 GO:0021502 biolink:BiologicalProcess neural fold elevation formation The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0021502 GO:0021503 biolink:BiologicalProcess neural fold bending The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0021503 CHEBI:71392 biolink:ChemicalSubstance tetracycline(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71392 GO:0070510 biolink:BiologicalProcess regulation of histone H4-K20 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. go-plus.json http://purl.obolibrary.org/obo/GO_0070510 GO:0070511 biolink:BiologicalProcess negative regulation of histone H4-K20 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. go-plus.json down-regulation of histone H4-K20 methylation|downregulation of histone H4-K20 methylation|down regulation of histone H4-K20 methylation|inhibition of histone H4-K20 methylation http://purl.obolibrary.org/obo/GO_0070511 GO:0021504 biolink:BiologicalProcess neural fold hinge point formation The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube. go-plus.json neural fold furrowing http://purl.obolibrary.org/obo/GO_0021504 CHEBI:71393 biolink:ChemicalSubstance adenosine thiamine triphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71393 chebi_ph7_3 CHEBI:71394 biolink:ChemicalSubstance adenosine thiamine triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71394 GO:0021505 biolink:BiologicalProcess neural fold folding The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds. go-plus.json http://purl.obolibrary.org/obo/GO_0021505 GO:0021506 biolink:BiologicalProcess anterior neuropore closure The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete. go-plus.json http://purl.obolibrary.org/obo/GO_0021506 GO:0021507 biolink:BiologicalProcess posterior neuropore closure The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete. go-plus.json http://purl.obolibrary.org/obo/GO_0021507 CHEBI:71397 biolink:ChemicalSubstance 8-oxo-dADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_71397 GO:0021508 biolink:BiologicalProcess floor plate formation The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. go-plus.json http://purl.obolibrary.org/obo/GO_0021508 GO:0045560 biolink:BiologicalProcess obsolete regulation of TRAIL receptor biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. go-plus.json regulation of TRAIL receptor biosynthesis|regulation of TRAIL receptor anabolism|regulation of TRAIL receptor synthesis|regulation of TRAIL receptor formation http://purl.obolibrary.org/obo/GO_0045560 CHEBI:46345 biolink:ChemicalSubstance 5-fluorouracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_46345 chebi_ph7_3 GO:0045567 biolink:BiologicalProcess obsolete negative regulation of TRAIL receptor 2 biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2. go-plus.json negative regulation of TRAIL receptor 2 biosynthesis|down-regulation of TRAIL receptor 2 biosynthetic process|inhibition of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 anabolism|negative regulation of TRAIL receptor 2 synthesis|negative regulation of TRAIL receptor 2 formation|down regulation of TRAIL receptor 2 biosynthetic process|downregulation of TRAIL receptor 2 biosynthetic process http://purl.obolibrary.org/obo/GO_0045567 CHEBI:22390 biolink:ChemicalSubstance alpha-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_22390 GO:0045568 biolink:BiologicalProcess obsolete positive regulation of TRAIL receptor 2 biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2. go-plus.json activation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 biosynthesis|stimulation of TRAIL receptor 2 biosynthetic process|up-regulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 anabolism|upregulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 synthesis|positive regulation of TRAIL receptor 2 formation|up regulation of TRAIL receptor 2 biosynthetic process http://purl.obolibrary.org/obo/GO_0045568 GO:0045565 biolink:BiologicalProcess obsolete negative regulation of TRAIL receptor 1 biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1. go-plus.json negative regulation of TRAIL receptor 1 biosynthesis|down-regulation of TRAIL receptor 1 biosynthetic process|inhibition of TRAIL receptor 1 biosynthetic process|negative regulation of TRAIL receptor 1 anabolism|negative regulation of TRAIL receptor 1 synthesis|negative regulation of TRAIL receptor 1 formation|down regulation of TRAIL receptor 1 biosynthetic process|downregulation of TRAIL receptor 1 biosynthetic process http://purl.obolibrary.org/obo/GO_0045565 GO:0045566 biolink:BiologicalProcess obsolete positive regulation of TRAIL receptor 1 biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1. go-plus.json stimulation of TRAIL receptor 1 biosynthetic process|up-regulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 anabolism|upregulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 synthesis|positive regulation of TRAIL receptor 1 formation|up regulation of TRAIL receptor 1 biosynthetic process|activation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 biosynthesis http://purl.obolibrary.org/obo/GO_0045566 GO:0045563 biolink:BiologicalProcess obsolete negative regulation of TRAIL receptor biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. go-plus.json negative regulation of TRAIL receptor synthesis|negative regulation of TRAIL receptor formation|down regulation of TRAIL receptor biosynthetic process|downregulation of TRAIL receptor biosynthetic process|down-regulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor biosynthesis|inhibition of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor anabolism http://purl.obolibrary.org/obo/GO_0045563 GO:0045564 biolink:BiologicalProcess obsolete positive regulation of TRAIL receptor biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. go-plus.json positive regulation of TRAIL receptor anabolism|upregulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor synthesis|positive regulation of TRAIL receptor formation|up regulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor biosynthesis|activation of TRAIL receptor biosynthetic process|stimulation of TRAIL receptor biosynthetic process|up-regulation of TRAIL receptor biosynthetic process http://purl.obolibrary.org/obo/GO_0045564 GO:0045561 biolink:BiologicalProcess obsolete regulation of TRAIL receptor 1 biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1. go-plus.json regulation of TRAIL receptor 1 anabolism|regulation of TRAIL receptor 1 biosynthesis|regulation of TRAIL receptor 1 synthesis|regulation of TRAIL receptor 1 formation http://purl.obolibrary.org/obo/GO_0045561 GO:0045562 biolink:BiologicalProcess obsolete regulation of TRAIL receptor 2 biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2. go-plus.json regulation of TRAIL receptor 2 anabolism|regulation of TRAIL receptor 2 biosynthesis|regulation of TRAIL receptor 2 synthesis|regulation of TRAIL receptor 2 formation http://purl.obolibrary.org/obo/GO_0045562 CHEBI:46342 biolink:ChemicalSubstance undecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_46342 chebi_ph7_3 GO:0070509 biolink:BiologicalProcess calcium ion import The directed movement of calcium ions into a cell or organelle. go-plus.json calcium ion uptake|transmembrane calcium influx http://purl.obolibrary.org/obo/GO_0070509 GO:0070507 biolink:BiologicalProcess regulation of microtubule cytoskeleton organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. go-plus.json regulation of microtubule cytoskeleton organisation|regulation of microtubule dynamics http://purl.obolibrary.org/obo/GO_0070507 GO:0070508 biolink:BiologicalProcess cholesterol import The directed movement of cholesterol into a cell or organelle. go-plus.json cholesterol uptake http://purl.obolibrary.org/obo/GO_0070508 GO:0070505 biolink:CellularComponent pollen coat A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma. go-plus.json pollenkitt|tryphine http://purl.obolibrary.org/obo/GO_0070505 GO:0070506 biolink:MolecularActivity high-density lipoprotein particle receptor activity Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis. go-plus.json high-density lipoprotein receptor activity|HDL receptor http://purl.obolibrary.org/obo/GO_0070506 GO:0045569 biolink:MolecularActivity TRAIL binding Binding to TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines. go-plus.json Apo-2L binding http://purl.obolibrary.org/obo/GO_0045569 goslim_chembl GO:0070503 biolink:BiologicalProcess selenium-containing prosthetic group metabolic process The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments. go-plus.json selenium-containing prosthetic group metabolism http://purl.obolibrary.org/obo/GO_0070503 GO:0070504 biolink:BiologicalProcess selenium-containing prosthetic group biosynthetic process The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments. go-plus.json selenium-containing prosthetic group synthesis|selenium-containing prosthetic group formation|selenium-containing prosthetic group biosynthesis|selenium-containing prosthetic group anabolism http://purl.obolibrary.org/obo/GO_0070504 GO:0070501 biolink:BiologicalProcess poly-gamma-glutamate biosynthetic process The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds. go-plus.json poly-gamma-glutamate anabolism|poly-gamma-glutamate biosynthesis|poly-gamma-glutamate synthesis|poly-gamma-glutamate formation http://purl.obolibrary.org/obo/GO_0070501 GO:0070502 biolink:BiologicalProcess capsule poly-gamma-glutamate biosynthetic process The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule. go-plus.json capsular poly-gamma-glutamate biosynthetic process|capsule poly-gamma-glutamate anabolism|capsule poly-gamma-glutamate synthesis|capsule poly-gamma-glutamate formation|capsule poly-gamma-glutamate biosynthesis http://purl.obolibrary.org/obo/GO_0070502 GO:0070500 biolink:BiologicalProcess poly-gamma-glutamate metabolic process The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds. go-plus.json poly-gamma-glutamate metabolism http://purl.obolibrary.org/obo/GO_0070500 GO:0045570 biolink:BiologicalProcess regulation of imaginal disc growth Any process that modulates the frequency, rate or extent of the growth of the imaginal disc. go-plus.json http://purl.obolibrary.org/obo/GO_0045570 GO:0045571 biolink:BiologicalProcess negative regulation of imaginal disc growth Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth. go-plus.json down-regulation of imaginal disc growth|downregulation of imaginal disc growth|down regulation of imaginal disc growth|inhibition of imaginal disc growth http://purl.obolibrary.org/obo/GO_0045571 GO:0045578 biolink:BiologicalProcess negative regulation of B cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. go-plus.json down regulation of B cell differentiation|inhibition of B cell differentiation|negative regulation of B-cell differentiation|negative regulation of B-lymphocyte differentiation|negative regulation of B cell development|down-regulation of B cell differentiation|negative regulation of B lymphocyte differentiation|downregulation of B cell differentiation http://purl.obolibrary.org/obo/GO_0045578 GO:0045579 biolink:BiologicalProcess positive regulation of B cell differentiation Any process that activates or increases the frequency, rate or extent of B cell differentiation. go-plus.json upregulation of B cell differentiation|stimulation of B cell differentiation|positive regulation of B-cell differentiation|activation of B cell differentiation|up-regulation of B cell differentiation|positive regulation of B-lymphocyte differentiation|positive regulation of B cell development|up regulation of B cell differentiation|positive regulation of B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045579 GO:0045576 biolink:BiologicalProcess mast cell activation The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0045576 GO:0045577 biolink:BiologicalProcess regulation of B cell differentiation Any process that modulates the frequency, rate or extent of B cell differentiation. go-plus.json regulation of B lymphocyte differentiation|regulation of B-cell differentiation|regulation of B-lymphocyte differentiation|regulation of B cell development http://purl.obolibrary.org/obo/GO_0045577 GO:0045574 biolink:BiologicalProcess sterigmatocystin catabolic process The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. go-plus.json sterigmatocystin degradation|sterigmatocystin catabolism|sterigmatocystin breakdown http://purl.obolibrary.org/obo/GO_0045574 GO:0045575 biolink:BiologicalProcess basophil activation The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors. Wikipedia:Basophil_activation go-plus.json http://purl.obolibrary.org/obo/GO_0045575 GO:0045572 biolink:BiologicalProcess positive regulation of imaginal disc growth Any process that activates or increases the frequency, rate or extent of imaginal disc growth. go-plus.json stimulation of imaginal disc growth|up-regulation of imaginal disc growth|activation of imaginal disc growth|up regulation of imaginal disc growth|upregulation of imaginal disc growth http://purl.obolibrary.org/obo/GO_0045572 GO:0045573 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045573 GO:0070538 biolink:MolecularActivity oleic acid binding Binding to oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070538 GO:0070539 biolink:MolecularActivity linoleic acid binding Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070539 GO:0070536 biolink:BiologicalProcess protein K63-linked deubiquitination A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070536 GO:0070537 biolink:BiologicalProcess histone H2A K63-linked deubiquitination A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX. go-plus.json http://purl.obolibrary.org/obo/GO_0070537 GO:0070534 biolink:BiologicalProcess protein K63-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair. go-plus.json protein K63-linked polyubiquitination http://purl.obolibrary.org/obo/GO_0070534 GO:0070535 biolink:BiologicalProcess histone H2A K63-linked ubiquitination A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX. go-plus.json http://purl.obolibrary.org/obo/GO_0070535 GO:0070532 biolink:CellularComponent BRCA1-B complex A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites. go-plus.json http://purl.obolibrary.org/obo/GO_0070532 GO:0070533 biolink:CellularComponent BRCA1-C complex A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_0070533 GO:0070530 biolink:MolecularActivity K63-linked polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070530 GO:0070531 biolink:CellularComponent BRCA1-A complex A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. go-plus.json http://purl.obolibrary.org/obo/GO_0070531 GO:0045581 biolink:BiologicalProcess negative regulation of T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. go-plus.json inhibition of T cell differentiation|negative regulation of T-cell differentiation|negative regulation of T-lymphocyte differentiation|negative regulation of T cell development|down-regulation of T cell differentiation|negative regulation of T lymphocyte differentiation|downregulation of T cell differentiation|down regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0045581 GO:0045582 biolink:BiologicalProcess positive regulation of T cell differentiation Any process that activates or increases the frequency, rate or extent of T cell differentiation. go-plus.json upregulation of T cell differentiation|stimulation of T cell differentiation|positive regulation of T-cell differentiation|up-regulation of T cell differentiation|activation of T cell differentiation|positive regulation of T-lymphocyte differentiation|positive regulation of T cell development|up regulation of T cell differentiation|positive regulation of T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045582 GO:0045580 biolink:BiologicalProcess regulation of T cell differentiation Any process that modulates the frequency, rate or extent of T cell differentiation. go-plus.json regulation of T lymphocyte differentiation|regulation of T-cell differentiation|regulation of T-lymphocyte differentiation|regulation of T cell development http://purl.obolibrary.org/obo/GO_0045580 GO:0045589 biolink:BiologicalProcess regulation of regulatory T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells. go-plus.json regulation of regulatory T lymphocyte differentiation|regulation of suppressor T lymphocyte differentiation|regulation of suppressor T-cell differentiation|regulation of regulatory T-cell differentiation|regulation of regulatory T-lymphocyte differentiation|regulation of suppressor T-lymphocyte differentiation|regulation of regulatory T cell development|regulation of suppressor T cell differentiation http://purl.obolibrary.org/obo/GO_0045589 GO:0045587 biolink:BiologicalProcess negative regulation of gamma-delta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation. go-plus.json negative regulation of gamma-delta T cell development|down-regulation of gamma-delta T cell differentiation|negative regulation of gamma-delta T lymphocyte differentiation|downregulation of gamma-delta T cell differentiation|down regulation of gamma-delta T cell differentiation|inhibition of gamma-delta T cell differentiation|negative regulation of gamma-delta T-cell differentiation|negative regulation of gamma-delta T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045587 GO:0045588 biolink:BiologicalProcess positive regulation of gamma-delta T cell differentiation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation. go-plus.json up-regulation of gamma-delta T cell differentiation|activation of gamma-delta T cell differentiation|positive regulation of gamma-delta T-lymphocyte differentiation|positive regulation of gamma-delta T cell development|up regulation of gamma-delta T cell differentiation|positive regulation of gamma-delta T lymphocyte differentiation|upregulation of gamma-delta T cell differentiation|stimulation of gamma-delta T cell differentiation|positive regulation of gamma-delta T-cell differentiation http://purl.obolibrary.org/obo/GO_0045588 GO:0045585 biolink:BiologicalProcess positive regulation of cytotoxic T cell differentiation Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation. go-plus.json up regulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T lymphocyte differentiation|upregulation of cytotoxic T cell differentiation|stimulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-cell differentiation|up-regulation of cytotoxic T cell differentiation|activation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-lymphocyte differentiation|positive regulation of cytotoxic T cell development http://purl.obolibrary.org/obo/GO_0045585 GO:0045586 biolink:BiologicalProcess regulation of gamma-delta T cell differentiation Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation. go-plus.json regulation of gamma-delta T-cell differentiation|regulation of gamma-delta T-lymphocyte differentiation|regulation of gamma-delta T cell development|regulation of gamma-delta T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045586 GO:0045583 biolink:BiologicalProcess regulation of cytotoxic T cell differentiation Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation. go-plus.json regulation of cytotoxic T cell development|regulation of cytotoxic T lymphocyte differentiation|regulation of cytotoxic T-cell differentiation|regulation of cytotoxic T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045583 GO:0045584 biolink:BiologicalProcess negative regulation of cytotoxic T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation. go-plus.json downregulation of cytotoxic T cell differentiation|down regulation of cytotoxic T cell differentiation|inhibition of cytotoxic T cell differentiation|negative regulation of cytotoxic T-cell differentiation|negative regulation of cytotoxic T-lymphocyte differentiation|negative regulation of cytotoxic T cell development|down-regulation of cytotoxic T cell differentiation|negative regulation of cytotoxic T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045584 GO:0070529 biolink:MolecularActivity L-tryptophan aminotransferase activity Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070529 GO:0070527 biolink:BiologicalProcess platelet aggregation The adhesion of one platelet to one or more other platelets via adhesion molecules. go-plus.json blood platelet aggregation|thrombocyte aggregation http://purl.obolibrary.org/obo/GO_0070527 GO:0070528 biolink:BiologicalProcess protein kinase C signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. go-plus.json PKC signal transduction|protein kinase C signal transduction|PKC signaling cascade|protein kinase C signalling cascade|protein kinase C signaling cascade http://purl.obolibrary.org/obo/GO_0070528 GO:0070525 biolink:BiologicalProcess tRNA threonylcarbamoyladenosine metabolic process The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. go-plus.json t6A metabolism|threonylcarbamoyladenosine metabolism|t6A metabolic process http://purl.obolibrary.org/obo/GO_0070525 GO:0070526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070526 GO:0070523 biolink:MolecularActivity 11-beta-hydroxysteroid dehydrogenase (NAD+) activity Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+. RHEA:53116|Wikipedia:11beta-hydroxysteroid_dehydrogenase go-plus.json http://purl.obolibrary.org/obo/GO_0070523 GO:0070524 biolink:MolecularActivity 11-beta-hydroxysteroid dehydrogenase (NADP+) activity Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+. MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|EC:1.1.1.146|Wikipedia:11beta-hydroxysteroid_dehydrogenase|RHEA:11388 go-plus.json beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0070524 GO:0070521 biolink:CellularComponent alpha4-beta1 integrin-CD82 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family. go-plus.json http://purl.obolibrary.org/obo/GO_0070521 GO:0070522 biolink:CellularComponent ERCC4-ERCC1 complex A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae. go-plus.json Rad1-Rad10 complex|XPF-ERCC1 complex http://purl.obolibrary.org/obo/GO_0070522 GO:0070520 biolink:CellularComponent alpha4-beta1 integrin-CD81 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family. go-plus.json ITGA4-ITGB1-CD81 complex http://purl.obolibrary.org/obo/GO_0070520 CHEBI:40 biolink:ChemicalSubstance (+)-pinoresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_40 chebi_ph7_3 CHEBI:61951 biolink:ChemicalSubstance microtubule-destabilising agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_61951 CHEBI:61952 biolink:ChemicalSubstance alpha-maltopentaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61952 chebi_ph7_3 CHEBI:61950 biolink:ChemicalSubstance microtubule-stabilising agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_61950 CHEBI:61953 biolink:ChemicalSubstance alpha-maltohexaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61953 chebi_ph7_3 CHEBI:61954 biolink:ChemicalSubstance alpha-maltoheptaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61954 chebi_ph7_3 CHEBI:85926 biolink:ChemicalSubstance (14Z)-hexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85926 chebi_ph7_3 CHEBI:85927 biolink:ChemicalSubstance (14E)-hexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85927 chebi_ph7_3 CHEBI:61958 biolink:ChemicalSubstance butane-1-sulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_61958 CHEBI:31 biolink:ChemicalSubstance (+)-menthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_31 chebi_ph7_3 CHEBI:61962 biolink:ChemicalSubstance S-oxy-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61962 CHEBI:61963 biolink:ChemicalSubstance 3-disulfanyl-L-alanine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61963 chebi_ph7_3 CHEBI:61961 biolink:ChemicalSubstance N(6),N(6),N(6)-trimethyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61961 chebi_ph7_3 CHEBI:85910 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85910 CHEBI:85911 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85911 CHEBI:61966 biolink:ChemicalSubstance metabotropic glutamate receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_61966 CHEBI:85912 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85912 CHEBI:61967 biolink:ChemicalSubstance 3-sulfino-L-alanine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61967 chebi_ph7_3 CHEBI:61964 biolink:ChemicalSubstance L-cysteine-S-dioxide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61964 chebi_ph7_3 CHEBI:61965 biolink:ChemicalSubstance trans-4-hydroxy-L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61965 chebi_ph7_3 CHEBI:85914 biolink:ChemicalSubstance (9Z,12Z)-hexadeca-9,12,15-trienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85914 chebi_ph7_3 CHEBI:61968 biolink:ChemicalSubstance cis-tetradec-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61968 chebi_ph7_3 CHEBI:61969 biolink:ChemicalSubstance N(6),N(6)-dimethyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61969 CHEBI:85919 biolink:ChemicalSubstance O-[S-(4Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85919 chebi_ph7_3 CHEBI:28 biolink:ChemicalSubstance (R)-linalool go-plus.json http://purl.obolibrary.org/obo/CHEBI_28 chebi_ph7_3 CHEBI:20 biolink:ChemicalSubstance (+)-camphene go-plus.json http://purl.obolibrary.org/obo/CHEBI_20 chebi_ph7_3 CHEBI:61970 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61970 chebi_ph7_3 CHEBI:61973 biolink:ChemicalSubstance S-hydroxy-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61973 chebi_ph7_3 CHEBI:61974 biolink:ChemicalSubstance 3-sulfino-L-alanine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61974 CHEBI:61971 biolink:ChemicalSubstance O-phospho-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61971 CHEBI:61972 biolink:ChemicalSubstance O(4)-phospho-L-tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61972 CHEBI:61977 biolink:ChemicalSubstance O-phosphonato-L-threonine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61977 chebi_ph7_3 CHEBI:61978 biolink:ChemicalSubstance O(4)-phosphonato-L-tyrosine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61978 CHEBI:61976 biolink:ChemicalSubstance N(6),N(6)-dimethyl-L-lysine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61976 chebi_ph7_3 GO:0021592 biolink:BiologicalProcess fourth ventricle development The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. go-plus.json http://purl.obolibrary.org/obo/GO_0021592 GO:0021593 biolink:BiologicalProcess rhombomere morphogenesis The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. go-plus.json http://purl.obolibrary.org/obo/GO_0021593 CHEBI:71300 biolink:ChemicalSubstance EC 2.* (transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_71300 GO:0021594 biolink:BiologicalProcess rhombomere formation The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. go-plus.json http://purl.obolibrary.org/obo/GO_0021594 GO:0021595 biolink:BiologicalProcess rhombomere structural organization The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. go-plus.json rhombomere structural organisation http://purl.obolibrary.org/obo/GO_0021595 CHEBI:71302 biolink:ChemicalSubstance MoO2-molybdopterin cofactor(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71302 chebi_ph7_3 CHEBI:71304 biolink:ChemicalSubstance L-gamma-glutamyl-L-amino acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71304 chebi_ph7_3 GO:0021597 biolink:BiologicalProcess central nervous system structural organization The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. go-plus.json central nervous system structural organisation http://purl.obolibrary.org/obo/GO_0021597 GO:0021598 biolink:BiologicalProcess abducens nerve morphogenesis The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. go-plus.json CN VI development http://purl.obolibrary.org/obo/GO_0021598 CHEBI:71305 biolink:ChemicalSubstance WO2-molybdopterin cofactor(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71305 chebi_ph7_3 GO:0021599 biolink:BiologicalProcess abducens nerve formation The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. go-plus.json CN VI formation|CN VI biosynthesis http://purl.obolibrary.org/obo/GO_0021599 CHEBI:71306 biolink:ChemicalSubstance MoO2-molybdopterin cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_71306 CHEBI:71307 biolink:ChemicalSubstance WO2-molybdopterin cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_71307 CHEBI:71308 biolink:ChemicalSubstance Mo(VI)-molybdopterin cytosine dinucleotide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71308 chebi_ph7_3 GO:0021590 biolink:BiologicalProcess cerebellum maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. go-plus.json http://purl.obolibrary.org/obo/GO_0021590 GO:0021591 biolink:BiologicalProcess ventricular system development The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. go-plus.json http://purl.obolibrary.org/obo/GO_0021591 CHEBI:61984 biolink:ChemicalSubstance (E)-2-methylgeranyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61984 chebi_ph7_3 CHEBI:61985 biolink:ChemicalSubstance 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61985 chebi_ph7_3 CHEBI:61982 biolink:ChemicalSubstance (E)-2-methylgeranyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61982 CHEBI:61983 biolink:ChemicalSubstance L-Ala-gamma-D-Glu-meso-Dap-D-Ala(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61983 chebi_ph7_3 CHEBI:61988 biolink:ChemicalSubstance alpha-maltotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61988 chebi_ph7_3 CHEBI:85934 biolink:ChemicalSubstance (2R)-2-hydroxytetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85934 CHEBI:61986 biolink:ChemicalSubstance maltotetraose tetrasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61986 CHEBI:61987 biolink:ChemicalSubstance 2-methylisoborneol go-plus.json http://purl.obolibrary.org/obo/CHEBI_61987 chebi_ph7_3 CHEBI:85937 biolink:ChemicalSubstance (2S)-2-hydroxytetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85937 CHEBI:85939 biolink:ChemicalSubstance cis-3-octenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85939 GO:0021581 biolink:BiologicalProcess medulla oblongata structural organization The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. go-plus.json myelencephalon structural maturation|medulla oblongata structural organisation|medulla structural maturation http://purl.obolibrary.org/obo/GO_0021581 CHEBI:71310 biolink:ChemicalSubstance Mo(VI)-molybdopterin guanine dinucleotide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71310 chebi_ph7_3 CHEBI:71311 biolink:ChemicalSubstance pyrazine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71311 GO:0021582 biolink:BiologicalProcess medulla oblongata maturation A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. go-plus.json medulla maturation|myelencephalon maturation http://purl.obolibrary.org/obo/GO_0021582 GO:0021583 biolink:BiologicalProcess pons morphogenesis The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. go-plus.json http://purl.obolibrary.org/obo/GO_0021583 CHEBI:71312 biolink:ChemicalSubstance bis(molybdopterin guanine dinucleotide)molybdenum(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71312 CHEBI:71313 biolink:ChemicalSubstance 4-carboxy-2-thioxobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71313 GO:0021584 biolink:BiologicalProcess pons formation The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. go-plus.json http://purl.obolibrary.org/obo/GO_0021584 GO:0021585 biolink:BiologicalProcess pons structural organization The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. go-plus.json pons structural organisation http://purl.obolibrary.org/obo/GO_0021585 CHEBI:89 biolink:ChemicalSubstance (-)-camphene go-plus.json http://purl.obolibrary.org/obo/CHEBI_89 chebi_ph7_3 GO:0021586 biolink:BiologicalProcess pons maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. go-plus.json http://purl.obolibrary.org/obo/GO_0021586 CHEBI:71315 biolink:ChemicalSubstance N'-monoacetylchitobiose-6'-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71315 chebi_ph7_3 CHEBI:71316 biolink:ChemicalSubstance (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_71316 chebi_ph7_3 GO:0021587 biolink:BiologicalProcess cerebellum morphogenesis The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. go-plus.json http://purl.obolibrary.org/obo/GO_0021587 CHEBI:71317 biolink:ChemicalSubstance N'-monoacetylchitobiose-6'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71317 GO:0021588 biolink:BiologicalProcess cerebellum formation The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. go-plus.json http://purl.obolibrary.org/obo/GO_0021588 CHEBI:80 biolink:ChemicalSubstance (-)-argemonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_80 CHEBI:61991 biolink:ChemicalSubstance maltotriose trisaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61991 CHEBI:61992 biolink:ChemicalSubstance sulfoacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61992 CHEBI:85960 biolink:ChemicalSubstance (3E)-nonenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85960 GO:0021580 biolink:BiologicalProcess medulla oblongata formation The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. go-plus.json myelencephalon biosynthesis|medulla formation|medulla biosynthesis|myelencephalon formation http://purl.obolibrary.org/obo/GO_0021580 CHEBI:61990 biolink:ChemicalSubstance 15,9'-di-cis-phytofluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_61990 chebi_ph7_3 CHEBI:85962 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-N-methylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85962 CHEBI:85963 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85963 CHEBI:61996 biolink:ChemicalSubstance maltopentaose pentasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_61996 CHEBI:61993 biolink:ChemicalSubstance maltotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_61993 chebi_ph7_3 CHEBI:61994 biolink:ChemicalSubstance sulfoacetyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61994 chebi_ph7_3 CHEBI:61999 biolink:ChemicalSubstance glucosyl-(heptosyl)2-4-phosphonatoheptosyl-(KDO)2-lipid A(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61999 chebi_ph7_3 PR:000007204 biolink:Protein estrogen receptor A protein that is a translation product of the human ESR1 gene or a 1:1 ortholog thereof. go-plus.json ESR|nuclear receptor subfamily 3 group A member 1|ER-alpha|NR3A1|Estra|ESR1|ER|Estr|estradiol receptor http://purl.obolibrary.org/obo/PR_000007204 CHEBI:61997 biolink:ChemicalSubstance glucosyl-(heptosyl)2-(KDO)2-lipid A(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61997 chebi_ph7_3 CHEBI:61998 biolink:ChemicalSubstance glucosyl-heptosyl-4-phosphonatoheptosyl-(KDO)2-lipid A(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61998 chebi_ph7_3 GO:0021589 biolink:BiologicalProcess cerebellum structural organization The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. go-plus.json cerebellum structural organisation http://purl.obolibrary.org/obo/GO_0021589 GO:0021570 biolink:BiologicalProcess rhombomere 4 development The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021570 CHEBI:71321 biolink:ChemicalSubstance fusidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71321 chebi_ph7_3 GO:0021571 biolink:BiologicalProcess rhombomere 5 development The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021571 GO:0021572 biolink:BiologicalProcess rhombomere 6 development The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021572 GO:0021573 biolink:BiologicalProcess rhombomere 7 development The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021573 GO:0021574 biolink:BiologicalProcess rhombomere 8 development The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021574 GO:0021575 biolink:BiologicalProcess hindbrain morphogenesis The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. go-plus.json rhombencephalon morphogenesis http://purl.obolibrary.org/obo/GO_0021575 GO:0021576 biolink:BiologicalProcess hindbrain formation The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. go-plus.json http://purl.obolibrary.org/obo/GO_0021576 GO:0021577 biolink:BiologicalProcess hindbrain structural organization The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. go-plus.json hindbrain structural organisation http://purl.obolibrary.org/obo/GO_0021577 CHEBI:141434 biolink:ChemicalSubstance monoacyl-3-O-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_141434 chebi_ph7_3 CHEBI:85951 biolink:ChemicalSubstance N-acyl-(4R,8Z)-4-hydroxysphing-8-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85951 chebi_ph7_3 CHEBI:85953 biolink:ChemicalSubstance N-acyl-(4E,8E)-sphinga-4,8-dienine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85953 chebi_ph7_3 CHEBI:85955 biolink:ChemicalSubstance (11E,13Z)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85955 CHEBI:85956 biolink:ChemicalSubstance (5Z,11E)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85956 CHEBI:85957 biolink:ChemicalSubstance (6Z,11E)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85957 CHEBI:85958 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-2'-O-methyladenosine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85958 chebi_ph7_3 GO:0021578 biolink:BiologicalProcess hindbrain maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. go-plus.json http://purl.obolibrary.org/obo/GO_0021578 CHEBI:85959 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-N(6)-methyl-2'-O-methyladenosine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_85959 chebi_ph7_3 GO:0021579 biolink:BiologicalProcess medulla oblongata morphogenesis The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. go-plus.json myelencephalon morphogenesis|medulla morphogenesis http://purl.obolibrary.org/obo/GO_0021579 CHEBI:71320 biolink:ChemicalSubstance cyclopeptine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71320 chebi_ph7_3 CHEBI:71332 biolink:ChemicalSubstance (3-nitro-4-oxidophenyl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71332 chebi_ph7_3 GO:0021560 biolink:BiologicalProcess abducens nerve development The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. go-plus.json CN VI development|cranial nerve 6 development|cranial nerve VI development http://purl.obolibrary.org/obo/GO_0021560 GO:0021561 biolink:BiologicalProcess facial nerve development The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. go-plus.json CN VII development|cranial nerve 7 development|cranial nerve VII development http://purl.obolibrary.org/obo/GO_0021561 GO:0021562 biolink:BiologicalProcess vestibulocochlear nerve development The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. go-plus.json CN VIII development|cranial nerve 8 development|cranial nerve VIII development|acoustic nerve development http://purl.obolibrary.org/obo/GO_0021562 CHEBI:71335 biolink:ChemicalSubstance (3R)-7,2'-dihydroxy-4'-methoxyisoflavanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_71335 chebi_ph7_3 GO:0021563 biolink:BiologicalProcess glossopharyngeal nerve development Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. go-plus.json CN IX development|cranial nerve 9 development|cranial nerve IX development http://purl.obolibrary.org/obo/GO_0021563 CHEBI:71337 biolink:ChemicalSubstance minocycline(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71337 GO:0021564 biolink:BiologicalProcess vagus nerve development The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. go-plus.json CN X development|cranial nerve X development|cranial nerve 10 development http://purl.obolibrary.org/obo/GO_0021564 GO:0021565 biolink:BiologicalProcess accessory nerve development The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. go-plus.json spinal accessory nerve development|CN XI development|cranial nerve 11 development|cranial nerve XI development http://purl.obolibrary.org/obo/GO_0021565 CHEBI:71338 biolink:ChemicalSubstance autoinducer go-plus.json http://purl.obolibrary.org/obo/CHEBI_71338 GO:0021566 biolink:BiologicalProcess hypoglossal nerve development The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. go-plus.json CN XII development|cranial nerve 12 development|cranial nerve XII development http://purl.obolibrary.org/obo/GO_0021566 CHEBI:71339 biolink:ChemicalSubstance novobiocin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71339 chebi_ph7_3 CHEBI:141420 biolink:ChemicalSubstance ganglioside GM2 (natural compound) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141420 CHEBI:85985 biolink:ChemicalSubstance 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85985 chebi_ph7_3 CHEBI:85986 biolink:ChemicalSubstance 3-deoxy-alpha-D-manno-oct-2-ulosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85986 chebi_ph7_3 CHEBI:85987 biolink:ChemicalSubstance CMP-3-deoxy-beta-D-manno-octulosonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85987 chebi_ph7_3 GO:0021567 biolink:BiologicalProcess rhombomere 1 development The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021567 GO:0021568 biolink:BiologicalProcess rhombomere 2 development The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021568 GO:0021569 biolink:BiologicalProcess rhombomere 3 development The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021569 CHEBI:71343 biolink:ChemicalSubstance Mo(VI)-molybdopterin guanine dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_71343 GO:0021550 biolink:BiologicalProcess medulla oblongata development The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. go-plus.json myelencephalon development|medulla development http://purl.obolibrary.org/obo/GO_0021550 CHEBI:71345 biolink:ChemicalSubstance norsolorinate anthrone(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71345 GO:0021551 biolink:BiologicalProcess central nervous system morphogenesis The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021551 CHEBI:71346 biolink:ChemicalSubstance norsolorinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71346 GO:0021552 biolink:BiologicalProcess midbrain-hindbrain boundary structural organization The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json isthmus structural organization|MHB structural organization|midbrain-hindbrain boundary structural organisation http://purl.obolibrary.org/obo/GO_0021552 GO:0021553 biolink:BiologicalProcess olfactory nerve development The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. go-plus.json CN 1 development|cranial nerve 1 development|cranial nerve I development http://purl.obolibrary.org/obo/GO_0021553 GO:0021554 biolink:BiologicalProcess optic nerve development The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. go-plus.json cranial nerve 2 development|CN II development|cranial nerve II development http://purl.obolibrary.org/obo/GO_0021554 GO:0021555 biolink:BiologicalProcess midbrain-hindbrain boundary morphogenesis The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. go-plus.json isthmus morphogenesis|MHB morphogenesis http://purl.obolibrary.org/obo/GO_0021555 GO:0045501 biolink:BiologicalProcess regulation of sevenless signaling pathway Any process that modulates the frequency, rate or extent of the sevenless signaling pathway. go-plus.json regulation of sev signaling pathway|regulation of sevenless signalling pathway http://purl.obolibrary.org/obo/GO_0045501 GO:0045502 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045502 CHEBI:53 biolink:ChemicalSubstance (+)-beta-phellandrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_53 chebi_ph7_3 GO:0045500 biolink:BiologicalProcess sevenless signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json sev signaling pathway|sevenless signalling pathway|sev receptor signaling pathway http://purl.obolibrary.org/obo/GO_0045500 CHEBI:85970 biolink:ChemicalSubstance hydroxyaurone go-plus.json http://purl.obolibrary.org/obo/CHEBI_85970 GO:0045509 biolink:MolecularActivity interleukin-27 receptor activity Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-27R|IL-27 receptor activity http://purl.obolibrary.org/obo/GO_0045509 GO:0045507 biolink:MolecularActivity interleukin-25 receptor activity Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-25R|IL-25 receptor activity http://purl.obolibrary.org/obo/GO_0045507 CHEBI:141417 biolink:ChemicalSubstance ganglioside GM2 (24:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141417 GO:0045508 biolink:MolecularActivity interleukin-26 receptor activity Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-26R|IL-26 receptor activity http://purl.obolibrary.org/obo/GO_0045508 GO:0045505 biolink:MolecularActivity dynein intermediate chain binding Binding to an intermediate chain of the dynein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0045505 GO:0045506 biolink:MolecularActivity interleukin-24 receptor activity Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-24R|IL-24 receptor activity http://purl.obolibrary.org/obo/GO_0045506 CHEBI:141416 biolink:ChemicalSubstance ganglioside GM2 (20:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141416 GO:0045503 biolink:MolecularActivity dynein light chain binding Binding to a light chain of the dynein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0045503 GO:0045504 biolink:MolecularActivity dynein heavy chain binding Binding to a heavy chain of the dynein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0045504 GO:0021556 biolink:BiologicalProcess central nervous system formation The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021556 GO:0021557 biolink:BiologicalProcess oculomotor nerve development The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. go-plus.json cranial nerve 3 development|CN III development|cranial nerve III development http://purl.obolibrary.org/obo/GO_0021557 GO:0021558 biolink:BiologicalProcess trochlear nerve development The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. go-plus.json CN IV development|cranial nerve 4 development|cranial nerve IV development http://purl.obolibrary.org/obo/GO_0021558 GO:0021559 biolink:BiologicalProcess trigeminal nerve development The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. go-plus.json CN V development|cranial nerve V development|cranial nerve 5 development http://purl.obolibrary.org/obo/GO_0021559 CHEBI:36904 biolink:ChemicalSubstance elemental selenium go-plus.json http://purl.obolibrary.org/obo/CHEBI_36904 CHEBI:12937 biolink:ChemicalSubstance D-galactose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12937 CHEBI:36902 biolink:ChemicalSubstance chalcogen hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36902 CHEBI:36903 biolink:ChemicalSubstance selenium hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36903 CHEBI:12936 biolink:ChemicalSubstance D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_12936 CHEBI:12931 biolink:ChemicalSubstance D-galactonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12931 chebi_ph7_3 CHEBI:36915 biolink:ChemicalSubstance inorganic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_36915 CHEBI:36916 biolink:ChemicalSubstance cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_36916 CHEBI:36914 biolink:ChemicalSubstance inorganic ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36914 CHEBI:36919 biolink:ChemicalSubstance antimony molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_36919 OBA:VT0002135 biolink:OntologyClass kidney morphology trait The morphology of a kidney. go-plus.json morphology of kidney http://purl.obolibrary.org/obo/OBA_VT0002135 UBERON:0003395 biolink:AnatomicalEntity mesentery of rectum A mesentery that is part of a rectum [Automatically generated definition]. go-plus.json rectum mesentery http://purl.obolibrary.org/obo/UBERON_0003395 CHEBI:12952 biolink:ChemicalSubstance aldehydo-D-galacturonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12952 chebi_ph7_3 UBERON:0003396 biolink:AnatomicalEntity mesentery of colon A mesentery that is part of a colon [Automatically generated definition]. go-plus.json mesocolon|large intestinal mesentery|large bowel mesentery|mesentery of large bowel|mesentery of large intestine|colon mesentery http://purl.obolibrary.org/obo/UBERON_0003396 UBERON:0003393 biolink:AnatomicalEntity mesentery of urinary system A mesentery that is part of a urinary system [Automatically generated definition]. go-plus.json mesentery of renal system|excretory system mesentery|urinary system mesentery|renal system mesentery|mesentery of systema urinaria|systema urinaria mesentery|mesentery of excretory system http://purl.obolibrary.org/obo/UBERON_0003393 UBERON:0003394 biolink:AnatomicalEntity mesentery of hindgut A mesentery that is part of a hindgut [Automatically generated definition]. go-plus.json hindgut mesentery http://purl.obolibrary.org/obo/UBERON_0003394 UBERON:0003390 biolink:AnatomicalEntity mesothelium of pleural cavity A mesothelium that is part of a pleural cavity [Automatically generated definition]. go-plus.json pleural cavity meso-epithelium|pleural mesothelium|pleural cavity mesothelium|pleura|mesothelium of pleura|meso-epithelium of pleural cavity http://purl.obolibrary.org/obo/UBERON_0003390 UBERON:0003397 biolink:AnatomicalEntity mesentery of duodenum A mesentery that is part of a duodenum [Automatically generated definition]. go-plus.json duodenum mesentery http://purl.obolibrary.org/obo/UBERON_0003397 UBERON:0003384 biolink:AnatomicalEntity skeletal muscle tissue of pharynx A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]. go-plus.json pharynx skeletal muscle tissue|pharynx skeletal muscle|skeletal muscle tissue of pharynx http://purl.obolibrary.org/obo/UBERON_0003384 UBERON:0003382 biolink:AnatomicalEntity cardiac muscle of left ventricle A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. go-plus.json left ventricle cardiac muscle|left ventricular cardiac muscle tissue|cardiac muscle tissue of left ventricle http://purl.obolibrary.org/obo/UBERON_0003382 UBERON:0003383 biolink:AnatomicalEntity cardiac muscle tissue of interventricular septum A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]. go-plus.json interventricular septum heart muscle|cardiac muscle tissue of interventricular septum|cardiac muscle of interventricular septum|interventricular septum cardiac muscle|interventricular septum myocardium|interventricular septum muscle http://purl.obolibrary.org/obo/UBERON_0003383 UBERON:0003380 biolink:AnatomicalEntity cardiac muscle of left atrium A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]. go-plus.json textus muscularis of myocardium of left atrium|textus muscularis of myocardium of cardiac left atrium|cardiac muscle of cardiac left atrium|left atrium myocardium|left atrium heart muscle|cardiac left atrium cardiac muscle tissue|myocardium of left atrium|cardiac muscle of heart left atrium|textus muscularis of myocardium of heart left atrium|textus muscularis of myocardium of left cardiac atrium|cardiac muscle of left atrium of heart|textus muscularis of myocardium of left atrium of heart|cardiac left atrium cardiac muscle http://purl.obolibrary.org/obo/UBERON_0003380 CHEBI:61900 biolink:ChemicalSubstance alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61900 CHEBI:61901 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61901 UBERON:0003381 biolink:AnatomicalEntity cardiac muscle of right ventricle A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. go-plus.json cardiac muscle tissue of right ventricle|right ventricular cardiac muscle tissue|right ventricle cardiac muscle http://purl.obolibrary.org/obo/UBERON_0003381 CHEBI:61904 biolink:ChemicalSubstance isethionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61904 chebi_ph7_3 CHEBI:61905 biolink:ChemicalSubstance short-chain fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61905 CHEBI:61902 biolink:ChemicalSubstance hydroxy fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61902 CHEBI:61903 biolink:ChemicalSubstance oxo-fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61903 UBERON:0003388 biolink:AnatomicalEntity mesothelium of pericardial cavity A mesothelium that is part of a pericardium [Automatically generated definition]. go-plus.json cavity of pericardial sac mesothelium|pericardial cavity meso-epithelium|mesothelium of cavity of pericardial sac|pericardial cavity mesothelium|cavity of pericardial sac meso-epithelium|meso-epithelium of pericardial cavity|meso-epithelium of cavity of pericardial sac http://purl.obolibrary.org/obo/UBERON_0003388 CHEBI:61908 biolink:ChemicalSubstance EC 1.14.13.39 (nitric oxide synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_61908 UBERON:0003389 biolink:AnatomicalEntity mesothelium of diaphragm A mesothelium that is part of a diaphragm [Automatically generated definition]. go-plus.json meso-epithelium of diaphragm|thoracic diaphragm meso-epithelium|diaphragm mesothelium|mesothelium of thoracic diaphragm|thoracic diaphragm mesothelium|diaphragm meso-epithelium|meso-epithelium of thoracic diaphragm http://purl.obolibrary.org/obo/UBERON_0003389 CHEBI:61909 biolink:ChemicalSubstance ethanesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61909 chebi_ph7_3 UBERON:0003386 biolink:AnatomicalEntity smooth muscle of eye any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi go-plus.json ocular smooth muscle http://purl.obolibrary.org/obo/UBERON_0003386 CHEBI:61906 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61906 OBA:VT0002121 biolink:OntologyClass metabolism trait The quality of a metabolic process. go-plus.json quality of metabolic process http://purl.obolibrary.org/obo/OBA_VT0002121 UBERON:0003387 biolink:AnatomicalEntity smooth muscle of trachea A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]. go-plus.json tracheal smooth muscle|trachea smooth muscle http://purl.obolibrary.org/obo/UBERON_0003387 CHEBI:61907 biolink:ChemicalSubstance medium-chain fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61907 CHEBI:61911 biolink:ChemicalSubstance butane-1-sulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61911 chebi_ph7_3 CHEBI:61912 biolink:ChemicalSubstance branched-chain fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61912 CHEBI:61910 biolink:ChemicalSubstance very long-chain fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61910 CHEBI:61915 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61915 CHEBI:61919 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61919 UBERON:1000004 biolink:AnatomicalEntity collection of hair on external ear A collection of hairs that grows on the external ear. go-plus.json external ear hair http://purl.obolibrary.org/obo/UBERON_1000004 CHEBI:61921 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61921 CHEBI:61927 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61927 NCBITaxon:1884633 biolink:OrganismalEntity Cryptococcaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1884633 CHEBI:61925 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61925 CHEBI:61928 biolink:ChemicalSubstance N(6)-methyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61928 CHEBI:61929 biolink:ChemicalSubstance N(6)-methyl-L-lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61929 chebi_ph7_3 CHEBI:61930 biolink:ChemicalSubstance N(6)-acetyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61930 chebi_ph7_3 CHEBI:61933 biolink:ChemicalSubstance glycerophosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61933 chebi_ph7_3 CHEBI:85900 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85900 CHEBI:85901 biolink:ChemicalSubstance epivancomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85901 CHEBI:61931 biolink:ChemicalSubstance glycerol 1-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61931 chebi_ph7_3 NCBITaxon:1639119 biolink:OrganismalEntity Plasmodiidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1639119 CHEBI:61932 biolink:ChemicalSubstance alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61932 CHEBI:61937 biolink:ChemicalSubstance alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61937 chebi_ph7_3 CHEBI:85904 biolink:ChemicalSubstance glutathione S-sulfinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85904 CHEBI:61938 biolink:ChemicalSubstance gamma-carboxy-L-glutamic acid zwitterion(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61938 chebi_ph7_3 CHEBI:85905 biolink:ChemicalSubstance cobalt(II)-factor IV go-plus.json http://purl.obolibrary.org/obo/CHEBI_85905 CHEBI:85906 biolink:ChemicalSubstance (2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_85906 chebi_ph7_3 CHEBI:61935 biolink:ChemicalSubstance alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61935 chebi_ph7_3 CHEBI:61936 biolink:ChemicalSubstance gamma-carboxy-L-glutamic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_61936 CHEBI:85907 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85907 CHEBI:85908 biolink:ChemicalSubstance 2-methyl-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_85908 chebi_ph7_3 CHEBI:85909 biolink:ChemicalSubstance 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85909 CHEBI:61939 biolink:ChemicalSubstance gamma-carboxy-L-glutamic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61939 CHEBI:141496 biolink:ChemicalSubstance 4-hydroxy-L-lysine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_141496 chebi_ph7_3 CHEBI:61940 biolink:ChemicalSubstance aroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_61940 CHEBI:61941 biolink:ChemicalSubstance gamma-carboxy-L-glutamic acid(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61941 chebi_ph7_3 CHEBI:61944 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61944 chebi_ph7_3 CHEBI:61945 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61945 chebi_ph7_3 CHEBI:61942 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61942 chebi_ph7_3 CHEBI:61943 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61943 chebi_ph7_3 CHEBI:61948 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61948 chebi_ph7_3 CHEBI:61949 biolink:ChemicalSubstance alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61949 chebi_ph7_3 CHEBI:61946 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61946 chebi_ph7_3 CHEBI:61947 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61947 chebi_ph7_3 GO:0045471 biolink:BiologicalProcess response to ethanol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0045471 GO:0045472 biolink:BiologicalProcess response to ether Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0045472 GO:0045470 biolink:BiologicalProcess R8 cell-mediated photoreceptor organization The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor. go-plus.json R8-mediated photoreceptor organisation http://purl.obolibrary.org/obo/GO_0045470 UBERON:0003328 biolink:AnatomicalEntity mesenchyme of footplate Mesenchyme that is part of a footplate. go-plus.json foot plate mesenchyme http://purl.obolibrary.org/obo/UBERON_0003328 UBERON:0003329 biolink:AnatomicalEntity submucosa of anal canal A submucosa that is part of an anal canal [Automatically generated definition]. go-plus.json submucosa of anal canal viewed anatomically|submucosa of anatomical anal canal|anal canal viewed anatomically submucosa|anal region submucosa|anal canal submucosa|anatomical anal canal submucosa|submucosa of anal region http://purl.obolibrary.org/obo/UBERON_0003329 GO:0045479 biolink:BiologicalProcess vesicle targeting to fusome The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome. go-plus.json vesicle-fusome targeting http://purl.obolibrary.org/obo/GO_0045479 GO:0045477 biolink:BiologicalProcess regulation of nurse cell apoptotic process Any process that modulates the frequency, rate or extent of nurse cell apoptotic process. go-plus.json regulation of nurse cell apoptosis http://purl.obolibrary.org/obo/GO_0045477 GO:0045478 biolink:BiologicalProcess fusome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells. go-plus.json fusome organisation|fusome organization and biogenesis http://purl.obolibrary.org/obo/GO_0045478 goslim_pir GO:0045475 biolink:BiologicalProcess locomotor rhythm The rhythm of the locomotor activity of an organism during its 24 hour activity cycle. go-plus.json circadian locomotor activity rhythm http://purl.obolibrary.org/obo/GO_0045475 GO:0045476 biolink:BiologicalProcess nurse cell apoptotic process Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process. go-plus.json nurse cell apoptosis|nurse cell programmed cell death by apoptosis|apoptosis of nurse cells|programmed cell death of nurse cells by apoptosis|invertebrate nurse cell apoptosis http://purl.obolibrary.org/obo/GO_0045476 CHEBI:22340 biolink:ChemicalSubstance all-cis-7,10,13-hexadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22340 GO:0045473 biolink:BiologicalProcess obsolete response to ethanol (sensu Insecta) OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. go-plus.json response to ethanol (sensu Insecta) http://purl.obolibrary.org/obo/GO_0045473 GO:0045474 biolink:BiologicalProcess obsolete response to ether (sensu Insecta) OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ether stimulus. go-plus.json response to ether (sensu Insecta) http://purl.obolibrary.org/obo/GO_0045474 UBERON:0003330 biolink:AnatomicalEntity submucosa of rectum The submucous layer of the wall of the rectum. go-plus.json rectal submucosa|tela submucosa recti|rectum submucosa http://purl.obolibrary.org/obo/UBERON_0003330 CHEBI:36982 biolink:ChemicalSubstance cyclic purine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36982 CHEBI:36983 biolink:ChemicalSubstance cyclic pyrimidine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36983 GO:0070439 biolink:CellularComponent Mad-Max-mSin3A complex A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p. go-plus.json http://purl.obolibrary.org/obo/GO_0070439 CHEBI:36988 biolink:ChemicalSubstance 5'-deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_36988 GO:0070437 biolink:CellularComponent Grb2-Shc complex A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway. go-plus.json Grb2-Shc complex, EGF stimulated http://purl.obolibrary.org/obo/GO_0070437 CHEBI:36986 biolink:ChemicalSubstance mesaconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_36986 chebi_ph7_3 GO:0070438 biolink:CellularComponent obsolete mTOR-FKBP12-rapamycin complex OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus). go-plus.json mTOR-FKBP12-rapamycin complex|Fkbp1a-Frap1 complex http://purl.obolibrary.org/obo/GO_0070438 CHEBI:36987 biolink:ChemicalSubstance 3'-deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_36987 GO:0070435 biolink:CellularComponent Shc-EGFR complex A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway. go-plus.json Shc-Egfr complex, EGF stimulated http://purl.obolibrary.org/obo/GO_0070435 GO:0070436 biolink:CellularComponent Grb2-EGFR complex A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway. go-plus.json Grb2-Egfr complex, EGF stimulated http://purl.obolibrary.org/obo/GO_0070436 UBERON:0003338 biolink:AnatomicalEntity ganglion of peripheral nervous system A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO). go-plus.json peripheral nervous system ganglion http://purl.obolibrary.org/obo/UBERON_0003338 UBERON:0003335 biolink:AnatomicalEntity serosa of colon A serous membrane that is part of a colon [Automatically generated definition]. go-plus.json large bowel serous membrane|large bowel serosa|serous membrane of colon|serosa of large bowel|colon serous membrane|colonic serosa|colon serosa|serous membrane of large bowel|visceral peritoneum of colon http://purl.obolibrary.org/obo/UBERON_0003335 GO:0070433 biolink:BiologicalProcess negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. go-plus.json negative regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|negative regulation of NOD2 signaling pathway http://purl.obolibrary.org/obo/GO_0070433 GO:0070434 biolink:BiologicalProcess positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. go-plus.json positive regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|positive regulation of NOD2 signaling pathway http://purl.obolibrary.org/obo/GO_0070434 UBERON:0003336 biolink:AnatomicalEntity serosa of duodenum A serous membrane that is part of a duodenum [Automatically generated definition]. go-plus.json duodenum serosa|serous membrane of duodenum|doudenal serosa|duodenum serous membrane|visceral peritoneum of duodenum|duodenal serosa http://purl.obolibrary.org/obo/UBERON_0003336 GO:0070431 biolink:BiologicalProcess nucleotide-binding oligomerization domain containing 2 signaling pathway Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2). go-plus.json NOD2 signaling pathway|nucleotide-binding oligomerization domain containing 2 signalling pathway http://purl.obolibrary.org/obo/GO_0070431 CHEBI:36980 biolink:ChemicalSubstance pyridine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36980 CHEBI:36981 biolink:ChemicalSubstance flavin nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36981 UBERON:0003334 biolink:AnatomicalEntity serosa of rectum A serous membrane that is part of a rectum [Automatically generated definition]. go-plus.json rectal serosa|serous membrane of rectum|rectum serous membrane|rectum serosa|visceral peritoneum of rectum http://purl.obolibrary.org/obo/UBERON_0003334 GO:0070432 biolink:BiologicalProcess regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. go-plus.json regulation of NOD2 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway http://purl.obolibrary.org/obo/GO_0070432 UBERON:0003331 biolink:AnatomicalEntity submucosa of colon A submucosa that is part of a colon [Automatically generated definition]. go-plus.json large bowel submucosa|colon submucosa|submucosa of large bowel|colonic submucosa http://purl.obolibrary.org/obo/UBERON_0003331 GO:0070430 biolink:BiologicalProcess positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway. go-plus.json positive regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway|positive regulation of NOD1 signaling pathway http://purl.obolibrary.org/obo/GO_0070430 UBERON:0003332 biolink:AnatomicalEntity submucosa of duodenum A submucosa that is part of a duodenum [Automatically generated definition]. go-plus.json doudenal submucosa|duodenum submucosa|duodenal submucosa http://purl.obolibrary.org/obo/UBERON_0003332 GO:0045482 biolink:MolecularActivity trichodiene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene. EC:4.2.3.6|RHEA:12052|MetaCyc:TRICHODIENE-SYNTHASE-RXN|KEGG_REACTION:R02306 go-plus.json trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)|trichodiene synthetase activity|trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity|sesquiterpene cyclase activity http://purl.obolibrary.org/obo/GO_0045482 GO:0045483 biolink:MolecularActivity aristolochene synthase activity Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate. EC:4.2.3.9|RHEA:19825|MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN go-plus.json sesquiterpene cyclase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)|trans,trans-farnesyl diphosphate aristolochene-lyase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming) http://purl.obolibrary.org/obo/GO_0045483 GO:0045480 biolink:MolecularActivity galactose oxidase activity Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide. MetaCyc:GALACTOSE-OXIDASE-RXN|EC:1.1.3.9|RHEA:24160 go-plus.json D-galactose oxidase activity|D-galactose:oxygen 6-oxidoreductase activity|beta-galactose oxidase activity http://purl.obolibrary.org/obo/GO_0045480 GO:0045481 biolink:MolecularActivity 6-endo-hydroxycineole dehydrogenase activity Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH. KEGG_REACTION:R02994|MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN|EC:1.1.1.241|RHEA:11736 go-plus.json 6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0045481 UBERON:0003319 biolink:AnatomicalEntity mesenchyme of carpal region Mesenchyme of the carpal region that contributes to the carpal skeleton. go-plus.json mesenchyme of wrist|carpal region mesenchyme|wrist mesenchyme|carpus mesenchyme http://purl.obolibrary.org/obo/UBERON_0003319 CHEBI:22359 biolink:ChemicalSubstance alloisoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22359 UBERON:0003318 biolink:AnatomicalEntity mesenchyme of elbow Mesenchyme that is part of a developing elbow [Automatically generated definition]. go-plus.json mesenchyme of cubital region|cubital region mesenchyme|elbow mesenchyme http://purl.obolibrary.org/obo/UBERON_0003318 GO:0045488 biolink:BiologicalProcess pectin metabolic process The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge. go-plus.json pectin metabolism http://purl.obolibrary.org/obo/GO_0045488 GO:0045489 biolink:BiologicalProcess pectin biosynthetic process The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. go-plus.json pectin anabolism|pectin biosynthesis|pectin synthesis|pectin formation http://purl.obolibrary.org/obo/GO_0045489 GO:0045486 biolink:MolecularActivity naringenin 3-dioxygenase activity Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2. RHEA:18621|MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN|EC:1.14.11.9 go-plus.json (2S)-flavanone 3-hydroxylase activity|naringenin 3-hydroxylase activity|flavanone 3-dioxygenase activity|flavanone 3-beta-hydroxylase activity|flavanone 3-hydroxylase activity|naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|flavanone synthase I activity|flavanone 3beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0045486 GO:0045487 biolink:BiologicalProcess gibberellin catabolic process The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators. go-plus.json gibberellic acid catabolic process|gibberellic acid catabolism|gibberellic acid degradation|gibberellin catabolism|gibberellic acid breakdown http://purl.obolibrary.org/obo/GO_0045487 GO:0045484 biolink:MolecularActivity L-lysine 6-transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine. RHEA:21200|MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R00457|EC:2.6.1.36 go-plus.json L-lysine transaminase activity|lysine epsilon-transaminase activity|L-lysine-alpha-ketoglutarate aminotransferase activity|lysine 6-aminotransferase activity|L-lysine aminotransferase activity|L-lysine:2-oxoglutarate 6-aminotransferase activity|lysine epsilon-aminotransferase activity|lysine:2-ketoglutarate 6-aminotransferase activity|L-lysine-alpha-ketoglutarate 6-aminotransferase activity http://purl.obolibrary.org/obo/GO_0045484 GO:0045485 biolink:MolecularActivity omega-6 fatty acid desaturase activity Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain. Reactome:R-HSA-2046092|Reactome:R-HSA-2046089 go-plus.json http://purl.obolibrary.org/obo/GO_0045485 CHEBI:36995 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36995 CHEBI:36993 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36993 CHEBI:36994 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36994 CHEBI:36999 biolink:ChemicalSubstance perillic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36999 GO:0070428 biolink:BiologicalProcess regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway. go-plus.json regulation of NOD1 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway http://purl.obolibrary.org/obo/GO_0070428 GO:0070429 biolink:BiologicalProcess negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway. go-plus.json negative regulation of NOD1 signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway http://purl.obolibrary.org/obo/GO_0070429 GO:0070426 biolink:BiologicalProcess positive regulation of nucleotide-binding oligomerization domain containing signaling pathway Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway. go-plus.json positive regulation of NOD signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing signalling pathway http://purl.obolibrary.org/obo/GO_0070426 GO:0070427 biolink:BiologicalProcess nucleotide-binding oligomerization domain containing 1 signaling pathway Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1). go-plus.json nucleotide-binding oligomerization domain containing 1 signalling pathway|NOD1 signaling pathway http://purl.obolibrary.org/obo/GO_0070427 UBERON:0003326 biolink:AnatomicalEntity mesenchyme of mammary gland Mesenchyme that is part of a developing mammary gland. go-plus.json mesenchyme of lobe of breast|lobe of breast mesenchyme|mesenchyme of lobe of mammary gland|mammary gland mesenchyme|mesenchyme of lactiferous gland|lactiferous gland mesenchyme|mammary mesenchyme|lobe of mammary gland mesenchyme http://purl.obolibrary.org/obo/UBERON_0003326 GO:0070424 biolink:BiologicalProcess regulation of nucleotide-binding oligomerization domain containing signaling pathway Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway. go-plus.json regulation of NOD signaling pathway|regulation of nucleotide-binding oligomerization domain containing signalling pathway http://purl.obolibrary.org/obo/GO_0070424 UBERON:0003327 biolink:AnatomicalEntity mesenchyme of forearm Mesenchyme that is part of a developing lower arm [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003327 GO:0070425 biolink:BiologicalProcess negative regulation of nucleotide-binding oligomerization domain containing signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway. go-plus.json negative regulation of NOD signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing signalling pathway http://purl.obolibrary.org/obo/GO_0070425 GO:0070422 biolink:CellularComponent G-protein beta/gamma-Raf-1 complex A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein. go-plus.json G protein complex (GNG2, GNB2L1, RAF1) http://purl.obolibrary.org/obo/GO_0070422 UBERON:0003324 biolink:AnatomicalEntity mesenchyme of lower jaw Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. go-plus.json lower jaw mesenchyme|mesenchyme of ventral mandibular arch|ventral mandibular arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0003324 UBERON:0003325 biolink:AnatomicalEntity mesenchyme of pinna Mesenchyme that is part of a developing pinna [Automatically generated definition]. go-plus.json auricle of ear mesenchyme|mesenchyme of auricula (auris externa)|mesenchyme of auricle of external ear|pinna of ear mesenchyme|mesenchyme of auricula|mesenchyme of auricle|pinna mesenchyme|auricle mesenchyme|auricula mesenchyme|mesenchyme of pinna of ear|auricula (auris externa) mesenchyme|auricle of external ear mesenchyme|mesenchyme of auricle of ear http://purl.obolibrary.org/obo/UBERON_0003325 GO:0070423 biolink:BiologicalProcess nucleotide-binding oligomerization domain containing signaling pathway Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein. go-plus.json NOD signaling pathway|nucleotide-binding oligomerization domain containing signalling pathway http://purl.obolibrary.org/obo/GO_0070423 UBERON:0003322 biolink:AnatomicalEntity mesenchyme of shoulder Mesenchyme that is part of a developing shoulder [Automatically generated definition]. go-plus.json shoulder mesenchyme http://purl.obolibrary.org/obo/UBERON_0003322 CHEBI:36991 biolink:ChemicalSubstance C-glycosyl pyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36991 GO:0070420 biolink:CellularComponent Ku-DNA ligase complex A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0070420 UBERON:0003323 biolink:AnatomicalEntity mesenchyme of upper jaw Mesenchyme that is part of a developing upper jaw [Automatically generated definition]. go-plus.json upper jaw mesenchyme|mesenchyme of palatoquadrate arch|palatoquadrate arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0003323 GO:0070421 biolink:CellularComponent DNA ligase III-XRCC1 complex A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair. go-plus.json http://purl.obolibrary.org/obo/GO_0070421 UBERON:0003320 biolink:AnatomicalEntity mesenchyme of hip Mesenchyme that is part of a developing hip [Automatically generated definition]. go-plus.json hip region mesenchyme|regio coxae mesenchyme|mesenchyme of regio coxae|hip mesenchyme|mesenchyme of hip region http://purl.obolibrary.org/obo/UBERON_0003320 UBERON:0003321 biolink:AnatomicalEntity mesenchyme of knee Mesenchyme that is part of a developing knee [Automatically generated definition]. go-plus.json knee mesenchyme http://purl.obolibrary.org/obo/UBERON_0003321 GO:0045493 biolink:BiologicalProcess xylan catabolic process The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone. go-plus.json xylan breakdown|xylan catabolism|xylan degradation http://purl.obolibrary.org/obo/GO_0045493 GO:0070450 biolink:CellularComponent interleukin4-interleukin-4 receptor complex A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule. go-plus.json IL4-IL4R-IL2RG complex|IL4-IL4 receptor complex http://purl.obolibrary.org/obo/GO_0070450 GO:0045494 biolink:BiologicalProcess photoreceptor cell maintenance Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light. go-plus.json http://purl.obolibrary.org/obo/GO_0045494 GO:0045491 biolink:BiologicalProcess xylan metabolic process The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone. go-plus.json xylan metabolism http://purl.obolibrary.org/obo/GO_0045491 GO:0045492 biolink:BiologicalProcess xylan biosynthetic process The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone. go-plus.json xylan biosynthesis|xylan anabolism|xylan synthesis|xylan formation http://purl.obolibrary.org/obo/GO_0045492 UBERON:0003308 biolink:AnatomicalEntity floor plate of telencephalon A floor plate that is part of a telencephalon [Automatically generated definition]. go-plus.json floor plate telencephalic region|floor plate telencephalon|telencephalon floor plate|telencephalon floorplate|floorplate of telencephalon|floorplate telencephalon http://purl.obolibrary.org/obo/UBERON_0003308 UBERON:0003309 biolink:AnatomicalEntity floor plate of diencephalon A floor plate that is part of a diencephalon [Automatically generated definition]. go-plus.json floor plate diencephalon|interbrain floorplate|floorplate of interbrain|mature diencephalon floor plate|between brain floorplate|floorplate of between brain|floor plate diencephalic region|floorplate diencephalon|floorplate of diencephalon|floor plate of interbrain|mature diencephalon floorplate|between brain floor plate|floor plate of mature diencephalon|interbrain floor plate|diencephalon floorplate|floorplate of mature diencephalon|diencephalon floor plate|floor plate of between brain http://purl.obolibrary.org/obo/UBERON_0003309 CHEBI:22326 biolink:ChemicalSubstance S-alkylsulfenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22326 chebi_ph7_3 GO:0045490 biolink:BiologicalProcess pectin catabolic process The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. go-plus.json pectin degradation|pectin breakdown|pectin catabolism http://purl.obolibrary.org/obo/GO_0045490 UBERON:0003306 biolink:AnatomicalEntity floor plate of neural tube A floor plate that is part of a neural tube [Automatically generated definition]. go-plus.json floorplate neural tube|floor plate neural tube|neural tube floor plate|neural tube floorplate|floorplate of neural tube http://purl.obolibrary.org/obo/UBERON_0003306 CHEBI:22323 biolink:ChemicalSubstance alkyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22323 UBERON:0003307 biolink:AnatomicalEntity floor plate of midbrain A floor plate that is part of a midbrain [Automatically generated definition]. go-plus.json midbrain floor plate|floor plate midbrain|floor plate midbrain region|floor plate mesencephalon|floorplate of midbrain|floorplate midbrain|midbrain floorplate http://purl.obolibrary.org/obo/UBERON_0003307 CHEBI:22324 biolink:ChemicalSubstance alkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22324 NCBITaxon:9526 biolink:OrganismalEntity Catarrhini go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9526 NCBITaxon:9527 biolink:OrganismalEntity Cercopithecidae go-plus.json Old World monkeys|monkey|monkeys http://purl.obolibrary.org/obo/NCBITaxon_9527 GO:0045499 biolink:MolecularActivity chemorepellent activity Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal. go-plus.json chemorepellant activity http://purl.obolibrary.org/obo/GO_0045499 goslim_pir NCBITaxon:9528 biolink:OrganismalEntity Cercopithecinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9528 CHEBI:36969 biolink:ChemicalSubstance farnesoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36969 GO:0045497 biolink:BiologicalProcess female analia development The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0045497 GO:0045498 biolink:BiologicalProcess sex comb development The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg. go-plus.json http://purl.obolibrary.org/obo/GO_0045498 GO:0045495 biolink:CellularComponent pole plasm Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo. go-plus.json germ plasm|polar plasm http://purl.obolibrary.org/obo/GO_0045495 GO:0045496 biolink:BiologicalProcess male analia development The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0045496 CHEBI:36962 biolink:ChemicalSubstance organochalcogen compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36962 CHEBI:36963 biolink:ChemicalSubstance organooxygen compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_36963 CHEBI:36960 biolink:ChemicalSubstance carbonothioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36960 CHEBI:36961 biolink:ChemicalSubstance chalcocarbonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36961 GO:0070459 biolink:BiologicalProcess prolactin secretion The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. go-plus.json http://purl.obolibrary.org/obo/GO_0070459 GO:0070457 biolink:MolecularActivity D-galactose-1-phosphate phosphatase activity Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0070457 UBERON:0003315 biolink:AnatomicalEntity mesenchyme of ovary Mesenchyme that is part of a developing ovary [Automatically generated definition]. go-plus.json mesenchyme of female reproductive system gonad|gonad of female reproductive system mesenchyme|mesenchyme of gonada of female reproductive system|female reproductive system gonada mesenchyme|mesenchyme of female reproductive system gonada|gonada of female reproductive system mesenchyme|ovary mesenchyme|mesenchyme of gonad of female reproductive system|female reproductive system gonad mesenchyme http://purl.obolibrary.org/obo/UBERON_0003315 CHEBI:22329 biolink:ChemicalSubstance alkyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22329 UBERON:0003316 biolink:AnatomicalEntity mesenchyme of yolk sac The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme. go-plus.json yolk sac mesenchyme http://purl.obolibrary.org/obo/UBERON_0003316 GO:0070458 biolink:BiologicalProcess cellular detoxification of nitrogen compound Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances. go-plus.json cellular detoxification of nitrogenous compound http://purl.obolibrary.org/obo/GO_0070458 GO:0070455 biolink:BiologicalProcess positive regulation of heme biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. go-plus.json upregulation of heme biosynthetic process|positive regulation of heme anabolism|positive regulation of heme synthesis|positive regulation of heme formation|up regulation of heme biosynthetic process|activation of heme biosynthetic process|positive regulation of heme biosynthesis|stimulation of heme biosynthetic process|up-regulation of heme biosynthetic process|positive regulation of haem biosynthetic process http://purl.obolibrary.org/obo/GO_0070455 CHEBI:22327 biolink:ChemicalSubstance aliphatic sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_22327 GO:0070456 biolink:MolecularActivity galactose-1-phosphate phosphatase activity Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0070456 UBERON:0003314 biolink:AnatomicalEntity eye mesenchyme Mesenchyme that is part of a developing camera-type eye. go-plus.json mesenchyme of eye http://purl.obolibrary.org/obo/UBERON_0003314 UBERON:0003311 biolink:AnatomicalEntity floor plate of medulla oblongata A floor plate that is part of a medulla oblongata [Automatically generated definition]. go-plus.json floorplate medulla oblongata|floorplate of bulb|floor plate medulla oblongata|medulla oblongata floor plate|floorplate of medulla oblonmgata|metepencephalon floorplate|metepencephalon floor plate|floor plate of bulb|medulla oblongata floorplate|floor plate of medulla oblonmgata|bulb floor plate|floor plate of metepencephalon|medulla oblonmgata floor plate|medulla oblonmgata floorplate|floorplate of medulla oblongata|bulb floorplate|floorplate of metepencephalon http://purl.obolibrary.org/obo/UBERON_0003311 GO:0070453 biolink:BiologicalProcess regulation of heme biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. go-plus.json regulation of heme biosynthesis|regulation of heme anabolism|regulation of heme synthesis|regulation of heme formation|regulation of haem biosynthetic process|regulation of haem biosynthesis http://purl.obolibrary.org/obo/GO_0070453 GO:0070454 biolink:BiologicalProcess negative regulation of heme biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. go-plus.json negative regulation of haem biosynthetic process|negative regulation of heme anabolism|negative regulation of heme synthesis|down regulation of heme biosynthetic process|negative regulation of heme formation|downregulation of heme biosynthetic process|negative regulation of heme biosynthesis|down-regulation of heme biosynthetic process|inhibition of heme biosynthetic process http://purl.obolibrary.org/obo/GO_0070454 UBERON:0003312 biolink:AnatomicalEntity mesenchyme of testis Mesenchyme that is part of a developing testis [Automatically generated definition]. go-plus.json testis mesenchyme http://purl.obolibrary.org/obo/UBERON_0003312 GO:0070451 biolink:CellularComponent cell hair A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. Wikipedia:Membrane_nanotube go-plus.json imaginal disc-derived wing hair|non-sensory hair http://purl.obolibrary.org/obo/GO_0070451 UBERON:0003310 biolink:AnatomicalEntity floor plate of metencephalon A floor plate that is part of a metencephalon [Automatically generated definition]. go-plus.json floorplate of metencephalon|floorplate of epencephalon-2|floorplate metencephalon|epencephalon-2 floorplate|floor plate metencephalon|metencephalon floor plate|floor plate of epencephalon-2|metencephalon floorplate|epencephalon-2 floor plate http://purl.obolibrary.org/obo/UBERON_0003310 GO:0070452 biolink:BiologicalProcess positive regulation of ergosterol biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol. go-plus.json up-regulation of ergosterol biosynthetic process|upregulation of ergosterol biosynthetic process|up regulation of ergosterol biosynthetic process|activation of ergosterol biosynthetic process|positive regulation of ergosterol anabolism|positive regulation of ergosterol biosynthesis|stimulation of ergosterol biosynthetic process|positive regulation of ergosterol synthesis|positive regulation of ergosterol formation http://purl.obolibrary.org/obo/GO_0070452 CHEBI:22332 biolink:ChemicalSubstance alkylamino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22332 CHEBI:22333 biolink:ChemicalSubstance alkylating agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_22333 CHEBI:22331 biolink:ChemicalSubstance alkylamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_22331 CHEBI:22335 biolink:ChemicalSubstance alkylglycerone phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22335 CHEBI:36979 biolink:ChemicalSubstance N-glycosylpyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36979 NCBITaxon:9539 biolink:OrganismalEntity Macaca go-plus.json macaques|macaque http://purl.obolibrary.org/obo/NCBITaxon_9539 UBERON:1000021 biolink:AnatomicalEntity skin of face A zone of skin that is part of the face. go-plus.json face skin|facial skin http://purl.obolibrary.org/obo/UBERON_1000021 CHEBI:36974 biolink:ChemicalSubstance aminoglycoside phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36974 CHEBI:36971 biolink:ChemicalSubstance dodecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36971 CHEBI:36972 biolink:ChemicalSubstance dodeca-2,6,10-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36972 NCBITaxon:9544 biolink:OrganismalEntity Macaca mulatta go-plus.json Rhesus monkey|rhesus macaque|rhesus macaques|rhesus monkeys http://purl.obolibrary.org/obo/NCBITaxon_9544 GO:0070448 biolink:MolecularActivity laricitrin 5'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin. KEGG_REACTION:R06816|MetaCyc:RXN-8452|RHEA:25633|EC:2.1.1.267 go-plus.json flavonoid 3',5'-O-dimethyltransferase activity|S-adenosyl-L-methionine:myricetin O-methyltransferase activity|CrCOMT2 http://purl.obolibrary.org/obo/GO_0070448 UBERON:1000023 biolink:AnatomicalEntity spleen pulp The parenchyma of the spleen, consisting of lymphocytes and macrophages. It lies between the splenic trabecula. Red pulp is the part suffused with blood and white pulp consists of areas of lymphatic tissue where there are sleeves of lymphocytes and macrophages. go-plus.json Malpighian corpuscles|splenic pulp|pulp of spleen http://purl.obolibrary.org/obo/UBERON_1000023 UBERON:1000024 biolink:AnatomicalEntity parenchyma of spleen A parenchyma that is part of a spleen. go-plus.json splenic parenchyma http://purl.obolibrary.org/obo/UBERON_1000024 GO:0070449 biolink:CellularComponent elongin complex A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits. go-plus.json transcription factor B (SIII) complex|transcription elongation factor SIII complex|elongin (SIII) complex http://purl.obolibrary.org/obo/GO_0070449 CHEBI:36976 biolink:ChemicalSubstance nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36976 GO:0070446 biolink:BiologicalProcess negative regulation of oligodendrocyte progenitor proliferation Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation. go-plus.json negative regulation of oligodendrocyte precursor proliferation http://purl.obolibrary.org/obo/GO_0070446 UBERON:0003304 biolink:AnatomicalEntity mesoderm blood island A blood island that is part of a mesoderm. go-plus.json mesenchyme blood island|mesoderm blood islands http://purl.obolibrary.org/obo/UBERON_0003304 GO:0070447 biolink:BiologicalProcess positive regulation of oligodendrocyte progenitor proliferation Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation. go-plus.json positive regulation of oligodendrocyte precursor proliferation http://purl.obolibrary.org/obo/GO_0070447 UBERON:0003302 biolink:AnatomicalEntity roof plate of metencephalon A roof plate that is part of a metencephalon [Automatically generated definition]. go-plus.json epencephalon-2 roof plate|metencephalon roofplate|roofplate of epencephalon-2|metencephalon roof plate|epencephalon-2 roofplate|roofplate medulla metencephalon|roofplate of metencephalon|roof plate metencephalon|roof plate of epencephalon-2 http://purl.obolibrary.org/obo/UBERON_0003302 GO:0070444 biolink:BiologicalProcess oligodendrocyte progenitor proliferation The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. go-plus.json oligodendrocyte precursor proliferation http://purl.obolibrary.org/obo/GO_0070444 UBERON:0003303 biolink:AnatomicalEntity roof plate of medulla oblongata A roof plate that is part of a medulla oblongata [Automatically generated definition]. go-plus.json roofplate of medulla oblonmgata|roofplate of medulla oblongata|bulb roofplate|roofplate of metepencephalon|medulla oblonmgata roof plate|medulla oblonmgata roofplate|roof plate of metepencephalon|bulb roof plate|roof plate medulla oblongata|roof plate of bulb|medulla oblongata roofplate|roof plate of medulla oblonmgata|metepencephalon roof plate|metepencephalon roofplate|roofplate medulla oblongata|roofplate of bulb|medulla oblongata roof plate http://purl.obolibrary.org/obo/UBERON_0003303 CHEBI:22339 biolink:ChemicalSubstance alkyne go-plus.json http://purl.obolibrary.org/obo/CHEBI_22339 GO:0070445 biolink:BiologicalProcess regulation of oligodendrocyte progenitor proliferation Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation. go-plus.json regulation of oligodendrocyte precursor proliferation http://purl.obolibrary.org/obo/GO_0070445 UBERON:0003300 biolink:AnatomicalEntity roof plate of telencephalon A roof plate that is part of a telencephalon [Automatically generated definition]. go-plus.json telencephalon roofplate|telencephalon roof plate|roofplate medulla telencephalon|roofplate of telencephalon|roof plate telencephalon http://purl.obolibrary.org/obo/UBERON_0003300 GO:0070442 biolink:CellularComponent integrin alphaIIb-beta3 complex An integrin complex that comprises one alphaIIb subunit and one beta3 subunit. go-plus.json ITGA2B-ITGB3 complex|alphaIIb-beta3 integrin complex http://purl.obolibrary.org/obo/GO_0070442 UBERON:0003301 biolink:AnatomicalEntity roof plate of diencephalon A roof plate that is part of a diencephalon [Automatically generated definition]. go-plus.json roof plate of interbrain|mature diencephalon roofplate|between brain roof plate|roof plate of between brain|roof plate diencephalon|roofplate of interbrain|between brain roofplate|mature diencephalon roof plate|roofplate of mature diencephalon|roofplate of diencephalon|interbrain roofplate|diencephalon roof plate|roof plate of mature diencephalon|diencephalon roofplate|roofplate medulla diencephalon|roofplate of between brain|roof plate diencephalic region|interbrain roof plate http://purl.obolibrary.org/obo/UBERON_0003301 CHEBI:36970 biolink:ChemicalSubstance vitamin B6 phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36970 GO:0070443 biolink:CellularComponent Mad-Max complex A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max. go-plus.json http://purl.obolibrary.org/obo/GO_0070443 GO:0070440 biolink:CellularComponent Mad-Max-mSin3B complex A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p. go-plus.json http://purl.obolibrary.org/obo/GO_0070440 GO:0070441 biolink:CellularComponent G-protein beta/gamma-Btk complex A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein. go-plus.json G protein complex (Btk, Gng2, Gnb1)|G protein complex (BTK, GNG1, GNG2) http://purl.obolibrary.org/obo/GO_0070441 GO:0070471 biolink:BiologicalProcess uterine smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth. go-plus.json myometrium contraction|myometrial smooth muscle contraction|myometrial contraction http://purl.obolibrary.org/obo/GO_0070471 GO:0070472 biolink:BiologicalProcess regulation of uterine smooth muscle contraction Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction. go-plus.json regulation of myometrial smooth muscle contraction|regulation of myometrial contraction|regulation of myometrium contraction http://purl.obolibrary.org/obo/GO_0070472 CHEBI:22300 biolink:ChemicalSubstance aldonic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22300 GO:0070470 biolink:CellularComponent plasma membrane respirasome A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. go-plus.json plasma membrane respiratory chain|plasma membrane electron transport chain http://purl.obolibrary.org/obo/GO_0070470 CHEBI:22301 biolink:ChemicalSubstance aldonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22301 CHEBI:22302 biolink:ChemicalSubstance aldonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_22302 CHEBI:36948 biolink:ChemicalSubstance oxoalkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36948 CHEBI:36949 biolink:ChemicalSubstance hydroxyalkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36949 CHEBI:36946 biolink:ChemicalSubstance thiourea go-plus.json http://purl.obolibrary.org/obo/CHEBI_36946 chebi_ph7_3 UBERON:0003373 biolink:AnatomicalEntity ectoderm of footplate An ectoderm that is part of a footplate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003373 UBERON:0003374 biolink:AnatomicalEntity chorionic ectoderm A extraembryonic structure that develops_from a ectoderm and is part of a chorion. go-plus.json chorionic epithelium|chorion epithelium|chorion ectoderm http://purl.obolibrary.org/obo/UBERON_0003374 NCBITaxon:9595 biolink:OrganismalEntity Gorilla gorilla gorilla go-plus.json western lowland gorilla|lowland gorilla http://purl.obolibrary.org/obo/NCBITaxon_9595 CHEBI:36941 biolink:ChemicalSubstance (S)-mandelonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_36941 chebi_ph7_3 NCBITaxon:9596 biolink:OrganismalEntity Pan go-plus.json chimpanzees http://purl.obolibrary.org/obo/NCBITaxon_9596 UBERON:0003371 biolink:AnatomicalEntity pelvic appendage bud ectoderm An unilaminar epithelium that surrounds a pelvic appendage bud. go-plus.json hindlimb ectoderm|pelvic fin bud ectoderm|leg ectoderm|hindlimb bud ectoderm|lower limb bud ectoderm|hindlimb ectoderm http://purl.obolibrary.org/obo/UBERON_0003371 UBERON:0003372 biolink:AnatomicalEntity pectoral appendage bud ectoderm An unilaminar epithelium that surrounds a pectoral appendage bud. go-plus.json wing ectoderm|forelimb ectoderm|pectoral fin bud ectoderm|forelimb bud ectoderm|upper limb bud ectoderm|arm ectoderm http://purl.obolibrary.org/obo/UBERON_0003372 NCBITaxon:9598 biolink:OrganismalEntity Pan troglodytes go-plus.json chimpanzee http://purl.obolibrary.org/obo/NCBITaxon_9598 CHEBI:36942 biolink:ChemicalSubstance pterin phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36942 CHEBI:36943 biolink:ChemicalSubstance aryl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36943 GO:0070479 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. go-plus.json nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' NMD|nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' nonsense-mediated mRNA decay|nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' nonsense-mediated decay http://purl.obolibrary.org/obo/GO_0070479 CHEBI:22307 biolink:ChemicalSubstance aldoxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_22307 chebi_ph7_3 GO:0070477 biolink:CellularComponent endospore core An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive. go-plus.json http://purl.obolibrary.org/obo/GO_0070477 UBERON:0003379 biolink:AnatomicalEntity cardiac muscle of right atrium A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]. go-plus.json textus muscularis of myocardium of right cardiac atrium|cardiac muscle of cardiac right atrium|right atrium myocardium|right atrium heart muscle|textus muscularis of myocardium of right atrium|cardiac muscle tissue of right atrium of heart|cardiac muscle of heart right atrium|cardiac muscle tissue of right atrium|myocardium of right atrium|textus muscularis of myocardium of right atrium of heart|cardiac muscle tissue of heart right atrium http://purl.obolibrary.org/obo/UBERON_0003379 GO:0070478 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. go-plus.json nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' NMD|nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' nonsense-mediated mRNA decay|nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' nonsense-mediated decay http://purl.obolibrary.org/obo/GO_0070478 GO:0070475 biolink:BiologicalProcess rRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070475 GO:0070476 biolink:BiologicalProcess rRNA (guanine-N7)-methylation The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0070476 GO:0070473 biolink:BiologicalProcess negative regulation of uterine smooth muscle contraction Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction. go-plus.json inhibition of uterine smooth muscle contraction|down regulation of uterine smooth muscle contraction|negative regulation of myometrium contraction|downregulation of uterine smooth muscle contraction|down-regulation of uterine smooth muscle contraction|negative regulation of myometrial smooth muscle contraction|negative regulation of myometrial contraction|uterine smooth muscle relaxation http://purl.obolibrary.org/obo/GO_0070473 NCBITaxon:9592 biolink:OrganismalEntity Gorilla go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_9592 GO:0070474 biolink:BiologicalProcess positive regulation of uterine smooth muscle contraction Any process that increases the frequency, rate or extent of uterine smooth muscle contraction. go-plus.json positive regulation of myometrial contraction|up-regulation of uterine smooth muscle contraction|upregulation of uterine smooth muscle contraction|positive regulation of myometrium contraction|up regulation of uterine smooth muscle contraction|activation of uterine smooth muscle contraction|stimulation of uterine smooth muscle contraction|positive regulation of myometrial smooth muscle contraction http://purl.obolibrary.org/obo/GO_0070474 NCBITaxon:9593 biolink:OrganismalEntity Gorilla gorilla go-plus.json western gorilla|Troglodytes gorilla|gorilla http://purl.obolibrary.org/obo/NCBITaxon_9593 GO:0070460 biolink:BiologicalProcess thyroid-stimulating hormone secretion The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary. go-plus.json thyroid stimulating hormone secretion|TSH secretion http://purl.obolibrary.org/obo/GO_0070460 GO:0070461 biolink:CellularComponent SAGA-type complex A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs). go-plus.json SAGA family complex http://purl.obolibrary.org/obo/GO_0070461 CHEBI:22314 biolink:ChemicalSubstance alkali metal atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_22314 CHEBI:22315 biolink:ChemicalSubstance alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22315 CHEBI:22313 biolink:ChemicalSubstance alkaline earth metal atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_22313 CHEBI:36959 biolink:ChemicalSubstance carbonothioic O,S-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36959 OBO:GOCHE_76946 biolink:OntologyClass substance with fungal metabolite role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76946 3_STAR CHEBI:36958 biolink:ChemicalSubstance carbonothioic O,O-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36958 CHEBI:36951 biolink:ChemicalSubstance aminoacyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36951 CHEBI:12962 biolink:ChemicalSubstance D-glucosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12962 CHEBI:36952 biolink:ChemicalSubstance carboxyalkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_36952 CHEBI:36954 biolink:ChemicalSubstance condensed ureas go-plus.json http://purl.obolibrary.org/obo/CHEBI_36954 GO:0070468 biolink:BiologicalProcess dentin extracellular matrix secretion The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin. go-plus.json dentine secretion|predentin secretion|dentin secretion http://purl.obolibrary.org/obo/GO_0070468 GO:0070469 biolink:CellularComponent respirasome The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. go-plus.json membrane electron transport chain|respiratory chain http://purl.obolibrary.org/obo/GO_0070469 CHEBI:22319 biolink:ChemicalSubstance alkanesulfinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22319 UBERON:0003368 biolink:AnatomicalEntity epithelium of hard palate An epithelium that is part of a hard palate [Automatically generated definition]. go-plus.json hard palate epithelium|epithelial tissue of hard palate|hard palate epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003368 GO:0070466 biolink:CellularComponent alpha2-beta1 integrin-alpha3(VI) complex A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain. go-plus.json ITGA2-ITGB1-COL6A3 complex http://purl.obolibrary.org/obo/GO_0070466 GO:0070467 biolink:CellularComponent RC-1 DNA recombination complex A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA. go-plus.json RC-1 complex (recombination complex 1)|DNA recombination complex RC-1 http://purl.obolibrary.org/obo/GO_0070467 GO:0070464 biolink:CellularComponent alphav-beta3 integrin-collagen alpha3(VI) complex A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen. go-plus.json http://purl.obolibrary.org/obo/GO_0070464 GO:0070465 biolink:CellularComponent alpha1-beta1 integrin-alpha3(VI) complex A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain. go-plus.json ITGA1-ITGB1-COL6A3 complex http://purl.obolibrary.org/obo/GO_0070465 UBERON:0003364 biolink:AnatomicalEntity epithelium of right lung An epithelium that is part of a right lung [Automatically generated definition]. go-plus.json right lung epithelium|epithelial tissue of right lung|right lung epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003364 GO:0070462 biolink:BiologicalProcess plus-end specific microtubule depolymerization The removal of tubulin heterodimers from the plus end of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0070462 UBERON:0003365 biolink:AnatomicalEntity epithelium of left lung An epithelium that is part of a left lung [Automatically generated definition]. go-plus.json left lung epithelium|epithelial tissue of left lung|left lung epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003365 GO:0070463 biolink:MolecularActivity tubulin-dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate. go-plus.json tubulin-activated ATPase activity http://purl.obolibrary.org/obo/GO_0070463 GO:0070493 biolink:BiologicalProcess thrombin-activated receptor signaling pathway The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. go-plus.json thrombin receptor signaling pathway|thrombin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0070493 GO:0070494 biolink:BiologicalProcess regulation of thrombin-activated receptor signaling pathway Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. go-plus.json regulation of thrombin receptor signaling pathway|regulation of thrombin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0070494 GO:0070491 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070491 GO:0070492 biolink:MolecularActivity oligosaccharide binding Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0070492 GO:0070490 biolink:BiologicalProcess protein pupylation The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein. go-plus.json Pup-protein conjugation|pupylation http://purl.obolibrary.org/obo/GO_0070490 CHEBI:36926 biolink:ChemicalSubstance but-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_36926 UBERON:0003351 biolink:AnatomicalEntity pharyngeal epithelium An epithelium that is part of a pharynx [Automatically generated definition]. go-plus.json pharynx epithelium|epithelium of pharynx|epithelial tissue of pharynx|pharynx epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003351 UBERON:0003352 biolink:AnatomicalEntity epithelium of midgut An epithelium that is part of a midgut. go-plus.json epithelial tissue of midgut|midgut epithelium|midgut epithelial tissue http://purl.obolibrary.org/obo/UBERON_0003352 UBERON:0003350 biolink:AnatomicalEntity epithelium of mucosa A layer of epithelial cells on the surface of the mucosa. go-plus.json lamina epithelialis mucosae|lamina epithelialis mucosa http://purl.obolibrary.org/obo/UBERON_0003350 CHEBI:36920 biolink:ChemicalSubstance antimony oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36920 CHEBI:36921 biolink:ChemicalSubstance antimony oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36921 UBERON:0003359 biolink:AnatomicalEntity epithelium of submandibular gland An epithelium that is part of a submandibular gland [Automatically generated definition]. go-plus.json submaxillary gland epithelium|submandibular duct epithelium|submandibular gland epithelium|epithelial tissue of submandibular gland|submandibular gland epithelial tissue|submandibular gland duct epithelium http://purl.obolibrary.org/obo/UBERON_0003359 UBERON:0003357 biolink:AnatomicalEntity epithelium of tongue An epithelium that is part of a tongue [Automatically generated definition]. go-plus.json epithelial tissue of tongue|tongue epithelial tissue|tongue epithelium|lingual epithelium http://purl.obolibrary.org/obo/UBERON_0003357 GO:0070499 biolink:BiologicalProcess exosporium assembly A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore. go-plus.json exosporium formation http://purl.obolibrary.org/obo/GO_0070499 UBERON:0003358 biolink:AnatomicalEntity epithelium of soft palate An epithelium that is part of a soft palate [Automatically generated definition]. go-plus.json soft palate epithelial tissue|soft palate epithelium|epithelial tissue of soft palate http://purl.obolibrary.org/obo/UBERON_0003358 GO:0070497 biolink:MolecularActivity 6-carboxy-5,6,7,8-tetrahydropterin synthase activity Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+. MetaCyc:RXN0-5507|RHEA:27966|EC:4.1.2.50 go-plus.json http://purl.obolibrary.org/obo/GO_0070497 GO:0070498 biolink:BiologicalProcess interleukin-1-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-1 alpha-mediated signaling pathway|interleukin-1-mediated signalling pathway|interleukin-1 beta-mediated signaling pathway|IL-1-mediated signaling pathway|IL-1 alpha-mediated signaling pathway|IL-1 beta-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0070498 GO:0070495 biolink:BiologicalProcess negative regulation of thrombin-activated receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. go-plus.json negative regulation of thrombin receptor signaling pathway|negative regulation of thrombin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0070495 UBERON:0003353 biolink:AnatomicalEntity epithelium of hindgut An epithelium that is part of a hindgut [Automatically generated definition]. go-plus.json epithelial tissue of hindgut|hindgut epithelial tissue|hindgut epithelium http://purl.obolibrary.org/obo/UBERON_0003353 UBERON:0003354 biolink:AnatomicalEntity epithelium of rectum An epithelium that is part of a rectum [Automatically generated definition]. go-plus.json epithelial tissue of rectum|rectum epithelium|rectum epithelial tissue|rectal epithelium http://purl.obolibrary.org/obo/UBERON_0003354 GO:0070496 biolink:BiologicalProcess positive regulation of thrombin-activated receptor signaling pathway Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. go-plus.json positive regulation of thrombin receptor signaling pathway|positive regulation of thrombin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0070496 GO:0070482 biolink:BiologicalProcess response to oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. go-plus.json http://purl.obolibrary.org/obo/GO_0070482 GO:0070483 biolink:BiologicalProcess detection of hypoxia The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. go-plus.json detection of reduced oxygen levels http://purl.obolibrary.org/obo/GO_0070483 GO:0070480 biolink:BiologicalProcess exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay. go-plus.json exonucleolytic nuclear-transcribed mRNA degradation involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA catabolism involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA breakdown involved in deadenylation-independent decay http://purl.obolibrary.org/obo/GO_0070480 GO:0070481 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, non-stop decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon. go-plus.json nonstop mRNA decay|nuclear-transcribed mRNA catabolism, non-stop decay|non-stop decay|nuclear-transcribed mRNA degradation, non-stop decay|nuclear-transcribed mRNA breakdown, non-stop decay|non-stop mRNA decay http://purl.obolibrary.org/obo/GO_0070481 UBERON:0003339 biolink:AnatomicalEntity ganglion of central nervous system A ganglion that is part of a central nervous system [Automatically generated definition]. go-plus.json neuraxis ganglion|ganglion of neuraxis|central nervous system ganglion http://purl.obolibrary.org/obo/UBERON_0003339 OBO:GOCHE_76924 biolink:OntologyClass substance with plant metabolite role go-plus.json http://purl.obolibrary.org/obo/GOCHE_76924 3_STAR UBERON:0003346 biolink:AnatomicalEntity mucosa of rectum A mucosa that is part of a rectum [Automatically generated definition]. go-plus.json rectum mucosa|mucous membrane of rectum|rectum mucosa of organ|rectum mucous membrane|organ mucosa of rectum|rectum organ mucosa|rectal mucosa|rectal mucous membrane|mucosa of organ of rectum http://purl.obolibrary.org/obo/UBERON_0003346 GO:0070488 biolink:BiologicalProcess neutrophil aggregation The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules. go-plus.json neutrophil leucocyte aggregation|neutrocyte aggregation|neutrophilic leucocyte aggregation|neutrophil leukocyte aggregation|neutrophilic leukocyte aggregation http://purl.obolibrary.org/obo/GO_0070488 GO:0070489 biolink:BiologicalProcess T cell aggregation The adhesion of one T cell to one or more other T cells via adhesion molecules. go-plus.json T lymphocyte aggregation|T-cell aggregation|T-lymphocyte aggregation http://purl.obolibrary.org/obo/GO_0070489 GO:0070486 biolink:BiologicalProcess leukocyte aggregation The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules. go-plus.json white blood cell aggregation|immune cell aggregation|leucocyte aggregation|white corpuscle aggregation http://purl.obolibrary.org/obo/GO_0070486 GO:0070487 biolink:BiologicalProcess monocyte aggregation The adhesion of one monocyte to one or more other monocytes via adhesion molecules. go-plus.json mononuclear phagocyte aggregation http://purl.obolibrary.org/obo/GO_0070487 UBERON:0003342 biolink:AnatomicalEntity mucosa of anal canal A mucosa that is part of an anal canal [Automatically generated definition]. go-plus.json anal region mucosa|mucous membrane of anatomical anal canal|mucosa of anatomical anal canal|anal canal viewed anatomically mucosa of organ|anal canal viewed anatomically mucosa|anal region mucosa of organ|organ mucosa of anal region|mucosa of organ of anal canal|anatomical anal canal organ mucosa|mucosa of organ of anatomical anal canal|anal canal viewed anatomically mucous membrane|anal canal organ mucosa|anal region mucous membrane|mucous membrane of anal canal|organ mucosa of anal canal viewed anatomically|anal mucous membrane|anal canal mucosa of organ|anatomical anal canal mucosa of organ|organ mucosa of anatomical anal canal|anal region organ mucosa|anal canal mucous membrane|anatomical anal canal mucosa|mucous membrane of anal region|anal canal viewed anatomically organ mucosa|anatomical anal canal mucous membrane|mucosa of anal region|anal canal mucosa|mucosa of organ of anal canal viewed anatomically|organ mucosa of anal canal|mucosa of organ of anal region|mucosa of anal canal viewed anatomically|anal mucosa|mucous membrane of anal canal viewed anatomically http://purl.obolibrary.org/obo/UBERON_0003342 GO:0070484 biolink:BiologicalProcess dehydro-D-arabinono-1,4-lactone metabolic process The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one. go-plus.json dehydro-D-arabinono-1,4-lactone metabolism http://purl.obolibrary.org/obo/GO_0070484 UBERON:0003343 biolink:AnatomicalEntity mucosa of oral region A mucosa that is part of a oral opening [Automatically generated definition]. go-plus.json oral opening mucous membrane|oral region mucous membrane|oral part of face organ mucosa|mucous membrane of oral part of face|mucosa of oral part of face|organ mucosa of oral opening|mucosa of organ of subdivision of mouth|subdivision of mouth organ mucosa|oral opening mucosa|mucosa of organ of oral part of face|mucous membrane of oral region|oral region mucosa|mucosa of subdivision of mouth|mucous membrane of subdivision of mouth|mucosa of organ of oral region|oral part of face mucosa|subdivision of mouth mucosa of organ|mucosa of organ of oral opening|subdivision of mouth mucous membrane|organ mucosa of oral part of face|subdivision of mouth mucosa|oral part of face mucosa of organ|mucosa of oral opening|mucous membrane of oral opening|oral opening mucosa of organ|oral part of face mucous membrane|organ mucosa of oral region|oral region mucosa of organ|oral opening organ mucosa|organ mucosa of subdivision of mouth|oral region organ mucosa http://purl.obolibrary.org/obo/UBERON_0003343 GO:0070485 biolink:BiologicalProcess dehydro-D-arabinono-1,4-lactone biosynthetic process The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one. go-plus.json dehydro-D-arabinono-1,4-lactone anabolism|dehydro-D-arabinono-1,4-lactone synthesis|dehydro-D-arabinono-1,4-lactone formation|dehydro-D-arabinono-1,4-lactone biosynthesis http://purl.obolibrary.org/obo/GO_0070485 CHEBI:71233 biolink:ChemicalSubstance 3-nitrotyramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71233 CHEBI:71234 biolink:ChemicalSubstance N-acyl-15-methylhexadecaphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71234 chebi_ph7_3 GO:0021660 biolink:BiologicalProcess rhombomere 3 formation The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021660 CHEBI:71235 biolink:ChemicalSubstance 4-hydroxy-3-nitrophenylacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_71235 GO:0021661 biolink:BiologicalProcess rhombomere 4 morphogenesis The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021661 CHEBI:71236 biolink:ChemicalSubstance feruloylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71236 CHEBI:71237 biolink:ChemicalSubstance thiophene-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71237 chebi_ph7_3 GO:0021662 biolink:BiologicalProcess rhombomere 4 structural organization The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 4 structural organisation http://purl.obolibrary.org/obo/GO_0021662 GO:0006029 biolink:BiologicalProcess proteoglycan metabolic process The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. go-plus.json proteoglycan metabolism|proteoglycan sulfate transfer http://purl.obolibrary.org/obo/GO_0006029 GO:0021663 biolink:BiologicalProcess rhombomere 4 formation The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021663 GO:0021664 biolink:BiologicalProcess rhombomere 5 morphogenesis The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021664 GO:0006027 biolink:BiologicalProcess glycosaminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. go-plus.json glycosaminoglycan catabolism|glycosaminoglycan breakdown|glycosaminoglycan degradation http://purl.obolibrary.org/obo/GO_0006027 CHEBI:71239 biolink:ChemicalSubstance (2Z)-4-carboxylato-2-sulfanylbut-2-enoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71239 GO:0021665 biolink:BiologicalProcess rhombomere 5 structural organization The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 5 structural organisation http://purl.obolibrary.org/obo/GO_0021665 GO:0006028 biolink:BiologicalProcess galactosaminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose. go-plus.json galactosaminoglycan degradation|galactosaminoglycan catabolism|galactosaminoglycan breakdown http://purl.obolibrary.org/obo/GO_0006028 GO:0006025 biolink:BiologicalProcess galactosaminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose. go-plus.json galactosaminoglycan synthesis|galactosaminoglycan formation|galactosaminoglycan biosynthesis|galactosaminoglycan anabolism http://purl.obolibrary.org/obo/GO_0006025 GO:0045633 biolink:BiologicalProcess positive regulation of mechanoreceptor differentiation Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. go-plus.json up regulation of mechanoreceptor differentiation|activation of mechanoreceptor differentiation|stimulation of mechanoreceptor differentiation|up-regulation of mechanoreceptor differentiation|upregulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045633 GO:0045634 biolink:BiologicalProcess regulation of melanocyte differentiation Any process that modulates the frequency, rate or extent of melanocyte differentiation. go-plus.json regulation of melanophore differentiation http://purl.obolibrary.org/obo/GO_0045634 GO:0006026 biolink:BiologicalProcess aminoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. go-plus.json aminoglycan degradation|aminoglycan breakdown|aminoglycan catabolism http://purl.obolibrary.org/obo/GO_0006026 GO:0045631 biolink:BiologicalProcess regulation of mechanoreceptor differentiation Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045631 GO:0006023 biolink:BiologicalProcess aminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. go-plus.json aminoglycan anabolism|aminoglycan biosynthesis|aminoglycan synthesis|aminoglycan formation http://purl.obolibrary.org/obo/GO_0006023 GO:0045632 biolink:BiologicalProcess negative regulation of mechanoreceptor differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation. go-plus.json downregulation of mechanoreceptor differentiation|down-regulation of mechanoreceptor differentiation|inhibition of mechanoreceptor differentiation|down regulation of mechanoreceptor differentiation http://purl.obolibrary.org/obo/GO_0045632 GO:0006024 biolink:BiologicalProcess glycosaminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. go-plus.json glycosaminoglycan biosynthesis|glycosaminoglycan anabolism|glycosaminoglycan synthesis|glycosaminoglycan formation http://purl.obolibrary.org/obo/GO_0006024 GO:0006021 biolink:BiologicalProcess inositol biosynthetic process The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. go-plus.json inositol synthesis|inositol formation|inositol biosynthesis|vitamin Bh biosynthetic process|vitamin Bh biosynthesis|myo-inositol biosynthesis|myo-inositol biosynthetic process|inositol anabolism http://purl.obolibrary.org/obo/GO_0006021 CHEBI:85881 biolink:ChemicalSubstance N-octanoylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85881 GO:0045630 biolink:BiologicalProcess positive regulation of T-helper 2 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation. go-plus.json stimulation of T-helper 2 cell differentiation|up-regulation of T-helper 2 cell differentiation|upregulation of T-helper 2 cell differentiation|up regulation of T-helper 2 cell differentiation|positive regulation of T-helper 2 cell development|activation of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045630 GO:0006022 biolink:BiologicalProcess aminoglycan metabolic process The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. go-plus.json aminoglycan metabolism http://purl.obolibrary.org/obo/GO_0006022 CHEBI:85882 biolink:ChemicalSubstance N-oleoylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_85882 GO:0006020 biolink:BiologicalProcess inositol metabolic process The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. Wikipedia:Inositol go-plus.json myo-inositol metabolic process|inositol metabolism|vitamin Bh metabolic process|vitamin Bh metabolism|myo-inositol metabolism http://purl.obolibrary.org/obo/GO_0006020 NCBITaxon:9397 biolink:OrganismalEntity Chiroptera go-plus.json bats|bats http://purl.obolibrary.org/obo/NCBITaxon_9397 CHEBI:85886 biolink:ChemicalSubstance 3-dehydrocarnityl CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85886 GO:0045639 biolink:BiologicalProcess positive regulation of myeloid cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. go-plus.json up-regulation of myeloid cell differentiation|activation of myeloid cell differentiation|up regulation of myeloid cell differentiation|upregulation of myeloid cell differentiation|stimulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045639 CHEBI:85888 biolink:ChemicalSubstance N,N,N-trimethylglycyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85888 CHEBI:85889 biolink:ChemicalSubstance (Z)-hex-3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85889 GO:0045637 biolink:BiologicalProcess regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of myeloid cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045637 GO:0045638 biolink:BiologicalProcess negative regulation of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. go-plus.json down-regulation of myeloid cell differentiation|downregulation of myeloid cell differentiation|down regulation of myeloid cell differentiation|inhibition of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045638 GO:0045635 biolink:BiologicalProcess negative regulation of melanocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation. go-plus.json downregulation of melanocyte differentiation|down regulation of melanocyte differentiation|inhibition of melanocyte differentiation|negative regulation of melanophore differentiation|down-regulation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0045635 GO:0045636 biolink:BiologicalProcess positive regulation of melanocyte differentiation Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. go-plus.json up regulation of melanocyte differentiation|upregulation of melanocyte differentiation|positive regulation of melanophore differentiation|stimulation of melanocyte differentiation|up-regulation of melanocyte differentiation|activation of melanocyte differentiation http://purl.obolibrary.org/obo/GO_0045636 GO:0021666 biolink:BiologicalProcess rhombomere 5 formation The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021666 GO:0021667 biolink:BiologicalProcess rhombomere 6 morphogenesis The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021667 GO:0021668 biolink:BiologicalProcess rhombomere 6 structural organization The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 6 structural organisation http://purl.obolibrary.org/obo/GO_0021668 GO:0021669 biolink:BiologicalProcess rhombomere 6 formation The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021669 CHEBI:71230 biolink:ChemicalSubstance dihydrochalcones go-plus.json http://purl.obolibrary.org/obo/CHEBI_71230 CHEBI:71231 biolink:ChemicalSubstance dihydrochalcone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71231 chebi_ph7_3 CHEBI:71232 biolink:ChemicalSubstance adenosine receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_71232 CHEBI:71244 biolink:ChemicalSubstance malonyl-CoA methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_71244 GO:0021650 biolink:BiologicalProcess vestibulocochlear nerve formation The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. go-plus.json CN VII formation http://purl.obolibrary.org/obo/GO_0021650 GO:0021651 biolink:BiologicalProcess rhombomere 1 morphogenesis The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021651 GO:0021652 biolink:BiologicalProcess rhombomere 1 formation The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021652 GO:0021653 biolink:BiologicalProcess rhombomere 1 structural organization The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 1 structural organisation http://purl.obolibrary.org/obo/GO_0021653 GO:0006038 biolink:BiologicalProcess cell wall chitin biosynthetic process The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. go-plus.json cell wall chitin anabolism|cell wall chitin synthesis|cell wall chitin biosynthesis|cell wall chitin formation http://purl.obolibrary.org/obo/GO_0006038 GO:0021654 biolink:BiologicalProcess rhombomere boundary formation The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021654 GO:0006039 biolink:BiologicalProcess cell wall chitin catabolic process The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. go-plus.json cell wall chitin degradation|cell wall chitin breakdown|cell wall chitin catabolism http://purl.obolibrary.org/obo/GO_0006039 GO:0045644 biolink:BiologicalProcess negative regulation of eosinophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation. go-plus.json down-regulation of eosinophil differentiation|downregulation of eosinophil differentiation|down regulation of eosinophil differentiation|inhibition of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0045644 GO:0006036 biolink:BiologicalProcess cuticle chitin catabolic process The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. go-plus.json cuticle chitin catabolism|cuticle chitin degradation|cuticle chitin breakdown http://purl.obolibrary.org/obo/GO_0006036 GO:0045645 biolink:BiologicalProcess positive regulation of eosinophil differentiation Any process that activates or increases the frequency, rate or extent of eosinophil differentiation. go-plus.json up regulation of eosinophil differentiation|upregulation of eosinophil differentiation|stimulation of eosinophil differentiation|up-regulation of eosinophil differentiation|activation of eosinophil differentiation http://purl.obolibrary.org/obo/GO_0045645 GO:0006037 biolink:BiologicalProcess cell wall chitin metabolic process The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. go-plus.json cell wall chitin metabolism http://purl.obolibrary.org/obo/GO_0006037 GO:0045642 biolink:BiologicalProcess positive regulation of basophil differentiation Any process that activates or increases the frequency, rate or extent of basophil differentiation. go-plus.json up-regulation of basophil differentiation|activation of basophil differentiation|up regulation of basophil differentiation|upregulation of basophil differentiation|stimulation of basophil differentiation http://purl.obolibrary.org/obo/GO_0045642 GO:0006034 biolink:BiologicalProcess cuticle chitin metabolic process The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. go-plus.json cuticle chitin metabolism http://purl.obolibrary.org/obo/GO_0006034 GO:0006035 biolink:BiologicalProcess cuticle chitin biosynthetic process The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. go-plus.json cuticle chitin anabolism|cuticle chitin synthesis|cuticle chitin formation|cuticle chitin biosynthesis http://purl.obolibrary.org/obo/GO_0006035 GO:0045643 biolink:BiologicalProcess regulation of eosinophil differentiation Any process that modulates the frequency, rate or extent of eosinophil differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045643 CHEBI:46261 biolink:ChemicalSubstance N-phenylthiourea go-plus.json http://purl.obolibrary.org/obo/CHEBI_46261 chebi_ph7_3 GO:0006032 biolink:BiologicalProcess chitin catabolic process The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. go-plus.json chitin breakdown|beta-1,4-linked N-acetylglucosamine catabolism|beta-1,4-linked N-acetylglucosamine catabolic process|chitin degradation|chitin catabolism http://purl.obolibrary.org/obo/GO_0006032 NCBITaxon:1111708 biolink:OrganismalEntity Synechocystis sp. PCC 6803 substr. Kazusa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1111708 GO:0045640 biolink:BiologicalProcess regulation of basophil differentiation Any process that modulates the frequency, rate or extent of basophil differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045640 GO:0045641 biolink:BiologicalProcess negative regulation of basophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation. go-plus.json down-regulation of basophil differentiation|downregulation of basophil differentiation|down regulation of basophil differentiation|inhibition of basophil differentiation http://purl.obolibrary.org/obo/GO_0045641 GO:0006033 biolink:BiologicalProcess chitin localization A process in which chitin is transported to, or maintained in, a specific location. go-plus.json chitin localisation|establishment and maintenance of chitin localization http://purl.obolibrary.org/obo/GO_0006033 GO:0006030 biolink:BiologicalProcess chitin metabolic process The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. go-plus.json chitin metabolism|beta-1,4-linked N-acetylglucosamine metabolic process|beta-1,4-linked N-acetylglucosamine metabolism http://purl.obolibrary.org/obo/GO_0006030 GO:0006031 biolink:BiologicalProcess chitin biosynthetic process The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. go-plus.json chitin anabolism|chitin synthesis|beta-1,4-linked N-acetylglucosamine biosynthetic process|beta-1,4-linked N-acetylglucosamine biosynthesis|chitin formation|chitin biosynthesis http://purl.obolibrary.org/obo/GO_0006031 GO:0006040 biolink:BiologicalProcess amino sugar metabolic process The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group. go-plus.json aminosaccharide metabolic process|amino sugar metabolism|aminosaccharide metabolism http://purl.obolibrary.org/obo/GO_0006040 CHEBI:85876 biolink:ChemicalSubstance triacylglycerol 54:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_85876 chebi_ph7_3 GO:0045648 biolink:BiologicalProcess positive regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. go-plus.json upregulation of erythrocyte differentiation|up regulation of erythrocyte differentiation|activation of erythrocyte differentiation|positive regulation of RBC differentiation|stimulation of erythrocyte differentiation|positive regulation of red blood cell differentiation|up-regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045648 GO:0045649 biolink:BiologicalProcess regulation of macrophage differentiation Any process that modulates the frequency, rate or extent of macrophage differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045649 GO:0045646 biolink:BiologicalProcess regulation of erythrocyte differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. go-plus.json regulation of red blood cell differentiation|regulation of RBC differentiation http://purl.obolibrary.org/obo/GO_0045646 GO:0045647 biolink:BiologicalProcess negative regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. go-plus.json down regulation of erythrocyte differentiation|downregulation of erythrocyte differentiation|negative regulation of red blood cell differentiation|negative regulation of RBC differentiation|down-regulation of erythrocyte differentiation|inhibition of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045647 GO:0021655 biolink:BiologicalProcess rhombomere 2 morphogenesis The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021655 GO:0021656 biolink:BiologicalProcess rhombomere 2 structural organization The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 2 structural organisation http://purl.obolibrary.org/obo/GO_0021656 GO:0021657 biolink:BiologicalProcess rhombomere 2 formation The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021657 GO:0021658 biolink:BiologicalProcess rhombomere 3 morphogenesis The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021658 GO:0021659 biolink:BiologicalProcess rhombomere 3 structural organization The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 3 structural organisation http://purl.obolibrary.org/obo/GO_0021659 CHEBI:71241 biolink:ChemicalSubstance thiophene-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71241 CHEBI:71242 biolink:ChemicalSubstance malonyl-CoA methyl ester(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71242 chebi_ph7_3 CHEBI:71243 biolink:ChemicalSubstance (2Z)-4-carboxy-2-sulfanylbut-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71243 CHEBI:22289 biolink:ChemicalSubstance aldaric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_22289 GO:0006009 biolink:BiologicalProcess glucose 1-phosphate phosphorylation The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0006009 CHEBI:71259 biolink:ChemicalSubstance selenodiglutathione(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71259 chebi_ph7_3 GO:0006007 biolink:BiologicalProcess glucose catabolic process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. go-plus.json glucose catabolism|glucose degradation|glucose breakdown http://purl.obolibrary.org/obo/GO_0006007 GO:0021640 biolink:BiologicalProcess trochlear nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. go-plus.json CN IV maturation http://purl.obolibrary.org/obo/GO_0021640 GO:0021641 biolink:BiologicalProcess trochlear nerve structural organization The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. go-plus.json trochlear nerve structural organisation|CN IV structural organization http://purl.obolibrary.org/obo/GO_0021641 GO:0006008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006008 GO:0021642 biolink:BiologicalProcess trochlear nerve formation The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. go-plus.json CN IV biosynthesis|CN IV formation http://purl.obolibrary.org/obo/GO_0021642 GO:0006005 biolink:BiologicalProcess L-fucose biosynthetic process The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose). go-plus.json L-fucose anabolism|L-fucose synthesis|L-fucose formation|L-fucose biosynthesis http://purl.obolibrary.org/obo/GO_0006005 GO:0006006 biolink:BiologicalProcess glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. go-plus.json cellular glucose metabolic process|glucose metabolism http://purl.obolibrary.org/obo/GO_0006006 GO:0021643 biolink:BiologicalProcess vagus nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. go-plus.json CN X maturation http://purl.obolibrary.org/obo/GO_0021643 GO:0045655 biolink:BiologicalProcess regulation of monocyte differentiation Any process that modulates the frequency, rate or extent of monocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045655 GO:0006003 biolink:BiologicalProcess fructose 2,6-bisphosphate metabolic process The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase. go-plus.json fructose 2,6-bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0006003 CHEBI:22280 biolink:ChemicalSubstance alanyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22280 GO:0045656 biolink:BiologicalProcess negative regulation of monocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. go-plus.json down-regulation of monocyte differentiation|downregulation of monocyte differentiation|down regulation of monocyte differentiation|inhibition of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045656 GO:0006004 biolink:BiologicalProcess fucose metabolic process The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose. go-plus.json fucose metabolism http://purl.obolibrary.org/obo/GO_0006004 GO:0045653 biolink:BiologicalProcess negative regulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. go-plus.json down-regulation of megakaryocyte differentiation|inhibition of megakaryocyte differentiation|down regulation of megakaryocyte differentiation|downregulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045653 GO:0006001 biolink:BiologicalProcess fructose catabolic process The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose. go-plus.json fructose catabolism|fructose breakdown|fructose degradation http://purl.obolibrary.org/obo/GO_0006001 GO:0045654 biolink:BiologicalProcess positive regulation of megakaryocyte differentiation Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. go-plus.json stimulation of megakaryocyte differentiation|up-regulation of megakaryocyte differentiation|upregulation of megakaryocyte differentiation|up regulation of megakaryocyte differentiation|activation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045654 GO:0006002 biolink:BiologicalProcess fructose 6-phosphate metabolic process The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism. go-plus.json fructose 6-phosphate metabolism http://purl.obolibrary.org/obo/GO_0006002 GO:0045651 biolink:BiologicalProcess positive regulation of macrophage differentiation Any process that activates or increases the frequency, rate or extent of macrophage differentiation. go-plus.json upregulation of macrophage differentiation|stimulation of macrophage differentiation|up-regulation of macrophage differentiation|activation of macrophage differentiation|up regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045651 GO:0006000 biolink:BiologicalProcess fructose metabolic process The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. Wikipedia:Fructose go-plus.json fructose metabolism http://purl.obolibrary.org/obo/GO_0006000 CHEBI:46252 biolink:ChemicalSubstance 5,6-diaminouracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_46252 chebi_ph7_3 GO:0045652 biolink:BiologicalProcess regulation of megakaryocyte differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045652 GO:0045650 biolink:BiologicalProcess negative regulation of macrophage differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. go-plus.json down-regulation of macrophage differentiation|downregulation of macrophage differentiation|down regulation of macrophage differentiation|inhibition of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045650 GO:0070619 biolink:CellularComponent Shc-Grb2-Sos complex A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. go-plus.json Shc-Grb2-mSos1 complex, EGF stimulated http://purl.obolibrary.org/obo/GO_0070619 GO:0070617 biolink:BiologicalProcess negative regulation of thiamine diphosphate biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate. go-plus.json downregulation of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate biosynthesis|down-regulation of thiamine diphosphate biosynthetic process|inhibition of thiamine diphosphate biosynthetic process|negative regulation of thiamin diphosphate biosynthetic process|negative regulation of thiamine diphosphate anabolism|negative regulation of thiamine diphosphate synthesis|negative regulation of thiamine diphosphate formation|down regulation of thiamine diphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0070617 GO:0070618 biolink:CellularComponent Grb2-Sos complex A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. go-plus.json Grb2-mSos1 complex http://purl.obolibrary.org/obo/GO_0070618 GO:0045659 biolink:BiologicalProcess negative regulation of neutrophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation. go-plus.json down-regulation of neutrophil differentiation|downregulation of neutrophil differentiation|down regulation of neutrophil differentiation|inhibition of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0045659 GO:0070615 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070615 GO:0070616 biolink:BiologicalProcess regulation of thiamine diphosphate biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate. go-plus.json regulation of thiamine diphosphate synthesis|regulation of thiamine diphosphate formation|regulation of thiamin diphosphate biosynthetic process|regulation of thiamine diphosphate anabolism|regulation of thiamine diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0070616 GO:0045657 biolink:BiologicalProcess positive regulation of monocyte differentiation Any process that activates or increases the frequency, rate or extent of monocyte differentiation. go-plus.json up regulation of monocyte differentiation|upregulation of monocyte differentiation|stimulation of monocyte differentiation|up-regulation of monocyte differentiation|activation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045657 GO:0070613 biolink:BiologicalProcess regulation of protein processing Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. go-plus.json regulation of protein maturation by peptide bond cleavage http://purl.obolibrary.org/obo/GO_0070613 GO:0045658 biolink:BiologicalProcess regulation of neutrophil differentiation Any process that modulates the frequency, rate or extent of neutrophil differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045658 GO:0070614 biolink:BiologicalProcess tungstate ion transport The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten. go-plus.json http://purl.obolibrary.org/obo/GO_0070614 GO:0070611 biolink:MolecularActivity histone methyltransferase activity (H3-R2 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3. go-plus.json histone methylase activity (H3-R2 specific)|histone-arginine N-methyltransferase activity (H3-R2 specific) http://purl.obolibrary.org/obo/GO_0070611 GO:0021644 biolink:BiologicalProcess vagus nerve morphogenesis The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. go-plus.json CN X morphogenesis http://purl.obolibrary.org/obo/GO_0021644 GO:0070612 biolink:MolecularActivity histone methyltransferase activity (H2A-R3 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A. go-plus.json histone methylase activity (H2A-R3 specific)|histone-arginine N-methyltransferase activity (H2A-R3 specific) http://purl.obolibrary.org/obo/GO_0070612 GO:0021645 biolink:BiologicalProcess vagus nerve structural organization The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. go-plus.json vagus nerve structural organisation|CN X structural organization http://purl.obolibrary.org/obo/GO_0021645 GO:0021646 biolink:BiologicalProcess vagus nerve formation The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. go-plus.json CN X biosynthesis|CN X formation http://purl.obolibrary.org/obo/GO_0021646 GO:0021647 biolink:BiologicalProcess vestibulocochlear nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. go-plus.json auditory nerve maturation|CN VIII maturation http://purl.obolibrary.org/obo/GO_0021647 GO:0070610 biolink:BiologicalProcess regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. go-plus.json regulation of fungal-type cell wall 1,3-alpha-glucan anabolism|regulation of fungal-type cell wall alpha-1,3-glucan anabolism|regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process|regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis|regulation of fungal-type cell wall alpha-1,3-glucan biosynthetic process|regulation of fungal-type cell wall alpha-1,3-glucan biosynthesis|regulation of fungal-type cell wall 1,3-alpha-glucan synthesis|regulation of fungal-type cell wall alpha-1,3-glucan synthesis|regulation of fungal-type cell wall 1,3-alpha-glucan formation|regulation of fungal-type cell wall alpha-1,3-glucan formation http://purl.obolibrary.org/obo/GO_0070610 GO:0021648 biolink:BiologicalProcess vestibulocochlear nerve morphogenesis The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. go-plus.json CN VIII morphogenesis http://purl.obolibrary.org/obo/GO_0021648 GO:0021649 biolink:BiologicalProcess vestibulocochlear nerve structural organization The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. go-plus.json CN VII structural organization|vestibulocochlear nerve structural organisation http://purl.obolibrary.org/obo/GO_0021649 CHEBI:71266 biolink:ChemicalSubstance pyrazine-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71266 chebi_ph7_3 CHEBI:22299 biolink:ChemicalSubstance aldonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22299 CHEBI:46245 biolink:ChemicalSubstance coenzyme Q10 go-plus.json http://purl.obolibrary.org/obo/CHEBI_46245 chebi_ph7_3 CHEBI:22297 biolink:ChemicalSubstance alditol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22297 GO:0006018 biolink:BiologicalProcess 2-deoxyribose 1-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose. go-plus.json 2-deoxyribose 1-phosphate degradation|2-deoxyribose 1-phosphate breakdown|2-deoxyribose 1-phosphate catabolism|deoxyribose 1-phosphate catabolic process http://purl.obolibrary.org/obo/GO_0006018 GO:0021630 biolink:BiologicalProcess olfactory nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. go-plus.json CN I maturation http://purl.obolibrary.org/obo/GO_0021630 GO:0006019 biolink:BiologicalProcess deoxyribose 5-phosphate phosphorylation The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0006019 GO:0021631 biolink:BiologicalProcess optic nerve morphogenesis The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. go-plus.json CN II morphogenesis http://purl.obolibrary.org/obo/GO_0021631 GO:0006016 biolink:BiologicalProcess 2-deoxyribose 1-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose. go-plus.json 2-deoxyribose 1-phosphate anabolism|2-deoxyribose 1-phosphate biosynthesis|2-deoxyribose 1-phosphate synthesis|2-deoxyribose 1-phosphate formation http://purl.obolibrary.org/obo/GO_0006016 GO:0006017 biolink:BiologicalProcess deoxyribose 1,5-bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose. go-plus.json deoxyribose 1,5-bisphosphate anabolism|deoxyribose 1,5-bisphosphate synthesis|deoxyribose 1,5-bisphosphate formation|deoxyribose 1,5-bisphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0006017 GO:0021632 biolink:BiologicalProcess optic nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. go-plus.json CN II maturation http://purl.obolibrary.org/obo/GO_0021632 GO:0045666 biolink:BiologicalProcess positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. go-plus.json up-regulation of neuron differentiation|activation of neuron differentiation|up regulation of neuron differentiation|upregulation of neuron differentiation|stimulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 GO:0006014 biolink:BiologicalProcess D-ribose metabolic process The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. go-plus.json D-ribose metabolism http://purl.obolibrary.org/obo/GO_0006014 GO:0006015 biolink:BiologicalProcess 5-phosphoribose 1-diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate. MetaCyc:PWY0-661 go-plus.json 5-phosphoribose 1-diphosphate biosynthesis|5-phosphoribose 1-diphosphate anabolism|5-phosphoribose 1-diphosphate synthesis|PRPP biosynthetic process|5-phosphoribose 1-diphosphate formation|5-phosphoribosyl-1-pyrophosphate biosynthetic process|5-phosphoribosyl-1-pyrophosphate biosynthesis http://purl.obolibrary.org/obo/GO_0006015 GO:0045667 biolink:BiologicalProcess regulation of osteoblast differentiation Any process that modulates the frequency, rate or extent of osteoblast differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045667 CHEBI:22292 biolink:ChemicalSubstance alditol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22292 GO:0006012 biolink:BiologicalProcess galactose metabolic process The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. Wikipedia:Galactose go-plus.json galactose metabolism http://purl.obolibrary.org/obo/GO_0006012 GO:0045664 biolink:BiologicalProcess regulation of neuron differentiation Any process that modulates the frequency, rate or extent of neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045664 GO:0045665 biolink:BiologicalProcess negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. go-plus.json down-regulation of neuron differentiation|downregulation of neuron differentiation|down regulation of neuron differentiation|inhibition of neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 GO:0006013 biolink:BiologicalProcess mannose metabolic process The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. go-plus.json mannose metabolism http://purl.obolibrary.org/obo/GO_0006013 CHEBI:85891 biolink:ChemicalSubstance N-isopropyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85891 CHEBI:22290 biolink:ChemicalSubstance aldaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22290 GO:0006010 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006010 GO:0045662 biolink:BiologicalProcess negative regulation of myoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json down-regulation of myoblast differentiation|downregulation of myoblast differentiation|down regulation of myoblast differentiation|inhibition of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045662 CHEBI:22295 biolink:ChemicalSubstance alditol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22295 GO:0006011 biolink:BiologicalProcess UDP-glucose metabolic process The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. go-plus.json UDP-glucose metabolism http://purl.obolibrary.org/obo/GO_0006011 GO:0045663 biolink:BiologicalProcess positive regulation of myoblast differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json up regulation of myoblast differentiation|upregulation of myoblast differentiation|stimulation of myoblast differentiation|activation of myoblast differentiation|up-regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045663 GO:0045660 biolink:BiologicalProcess positive regulation of neutrophil differentiation Any process that activates or increases the frequency, rate or extent of neutrophil differentiation. go-plus.json stimulation of neutrophil differentiation|up-regulation of neutrophil differentiation|activation of neutrophil differentiation|up regulation of neutrophil differentiation|upregulation of neutrophil differentiation http://purl.obolibrary.org/obo/GO_0045660 CHEBI:85894 biolink:ChemicalSubstance N-(gamma-L-glutamyl)-L-alaninol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85894 GO:0045661 biolink:BiologicalProcess regulation of myoblast differentiation Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0045661 CHEBI:22294 biolink:ChemicalSubstance alditol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22294 CHEBI:85895 biolink:ChemicalSubstance 4-amino-5-formamidomethyl-2-methylpyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85895 chebi_ph7_3 GO:0070608 biolink:BiologicalProcess regulation of cell wall (1->3)-alpha-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. go-plus.json regulation of cell wall 1,3-alpha-glucan anabolism|regulation of cell wall alpha-1,3-glucan anabolism|regulation of cell wall 1,3-alpha-glucan synthesis|regulation of cell wall alpha-1,3-glucan synthesis|regulation of cell wall 1,3-alpha-glucan formation|regulation of cell wall alpha-1,3-glucan formation|regulation of cell wall alpha-1,3-glucan biosynthesis|regulation of cell wall alpha-1,3-glucan biosynthetic process|regulation of cell wall 1,3-alpha-glucan biosynthetic process|regulation of cell wall 1,3-alpha-glucan biosynthesis http://purl.obolibrary.org/obo/GO_0070608 CHEBI:85897 biolink:ChemicalSubstance 11-deoxy-beta-rhodomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_85897 GO:0070609 biolink:BiologicalProcess regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores. go-plus.json regulation of ascospore wall alpha-1,3 glucan metabolism|regulation of ascospore wall alpha-1,3 glucan metabolic process|regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process|regulation of ascospore wall 1,3-alpha-glucan metabolism http://purl.obolibrary.org/obo/GO_0070609 GO:0070606 biolink:BiologicalProcess regulation of (1->3)-alpha-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. go-plus.json regulation of 1,3-alpha-glucan anabolism|regulation of 1,3-alpha-glucan synthesis|regulation of 1,3-alpha-glucan formation|regulation of alpha-1,3 glucan biosynthesis|regulation of alpha-1,3 glucan anabolism|regulation of alpha-1,3 glucan biosynthetic process|regulation of alpha-1,3 glucan synthesis|regulation of alpha-1,3 glucan formation|regulation of 1,3-alpha-glucan biosynthetic process|regulation of 1,3-alpha-glucan biosynthesis http://purl.obolibrary.org/obo/GO_0070606 CHEBI:85899 biolink:ChemicalSubstance 4-pregnen-3beta-ol-20-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85899 chebi_ph7_3 GO:0070607 biolink:BiologicalProcess regulation of cell wall (1->3)-alpha-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. go-plus.json regulation of cell wall alpha-1,3 glucan metabolism|regulation of cell wall alpha-1,3 glucan metabolic process|regulation of cell wall 1,3-alpha-glucan metabolism|regulation of cell wall 1,3-alpha-glucan metabolic process http://purl.obolibrary.org/obo/GO_0070607 GO:0070604 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070604 GO:0070605 biolink:BiologicalProcess regulation of (1->3)-alpha-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. go-plus.json regulation of alpha-1,3 glucan metabolic process|regulation of alpha-1,3 glucan metabolism|regulation of 1,3-alpha-glucan metabolic process|regulation of 1,3-alpha-glucan metabolism http://purl.obolibrary.org/obo/GO_0070605 GO:0070602 biolink:BiologicalProcess regulation of centromeric sister chromatid cohesion Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome. go-plus.json regulation of sister chromatid cohesion at centromere http://purl.obolibrary.org/obo/GO_0070602 GO:0045668 biolink:BiologicalProcess negative regulation of osteoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. go-plus.json downregulation of osteoblast differentiation|down regulation of osteoblast differentiation|inhibition of osteoblast differentiation|down-regulation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045668 GO:0070603 biolink:CellularComponent SWI/SNF superfamily-type complex A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP. go-plus.json SWI-SNF global transcription activator complex|SWI/SNF-type complex|SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex|BAF-type complex|SWI-SNF-type complex http://purl.obolibrary.org/obo/GO_0070603 gocheck_do_not_manually_annotate GO:0045669 biolink:BiologicalProcess positive regulation of osteoblast differentiation Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. go-plus.json up regulation of osteoblast differentiation|upregulation of osteoblast differentiation|stimulation of osteoblast differentiation|up-regulation of osteoblast differentiation|activation of osteoblast differentiation http://purl.obolibrary.org/obo/GO_0045669 GO:0021633 biolink:BiologicalProcess optic nerve structural organization The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. go-plus.json optic nerve structural organisation|CN II structural organization http://purl.obolibrary.org/obo/GO_0021633 GO:0070600 biolink:BiologicalProcess fungal-type cell wall (1->3)-alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. go-plus.json fungal-type cell wall 1,3-alpha-glucan biosynthesis|fungal-type cell wall 1,3-alpha-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan biosynthesis|fungal-type cell wall alpha-1,3-glucan anabolism|fungal-type cell wall 1,3-alpha-glucan anabolism|fungal-type cell wall alpha-1,3-glucan synthesis|fungal-type cell wall 1,3-alpha-glucan synthesis|fungal-type cell wall alpha-1,3-glucan formation|fungal-type cell wall 1,3-alpha-glucan formation http://purl.obolibrary.org/obo/GO_0070600 GO:0070601 biolink:BiologicalProcess centromeric sister chromatid cohesion The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome. go-plus.json sister chromatid cohesion at centromere http://purl.obolibrary.org/obo/GO_0070601 GO:0021634 biolink:BiologicalProcess optic nerve formation The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. go-plus.json CN II biosynthesis|CN II formation http://purl.obolibrary.org/obo/GO_0021634 GO:0021635 biolink:BiologicalProcess trigeminal nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. go-plus.json CN V maturation http://purl.obolibrary.org/obo/GO_0021635 CHEBI:71261 biolink:ChemicalSubstance S-(2-hydroxyacyl)glutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71261 chebi_ph7_3 GO:0021636 biolink:BiologicalProcess trigeminal nerve morphogenesis The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. go-plus.json CN V morphogenesis http://purl.obolibrary.org/obo/GO_0021636 GO:0021637 biolink:BiologicalProcess trigeminal nerve structural organization The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. go-plus.json trigeminal nerve structural organisation|CN V structural organization http://purl.obolibrary.org/obo/GO_0021637 GO:0021638 biolink:BiologicalProcess trigeminal nerve formation The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. go-plus.json CN V formation|CN V biosynthesis http://purl.obolibrary.org/obo/GO_0021638 GO:0021639 biolink:BiologicalProcess trochlear nerve morphogenesis The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. go-plus.json CH IV morphogenesis http://purl.obolibrary.org/obo/GO_0021639 CHEBI:71265 biolink:ChemicalSubstance glutathioselenol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71265 chebi_ph7_3 CHEBI:22266 biolink:ChemicalSubstance adipate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_22266 CHEBI:71277 biolink:ChemicalSubstance 4-carboxylato-2-thioxobutanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71277 chebi_ph7_3 GO:0045670 biolink:BiologicalProcess regulation of osteoclast differentiation Any process that modulates the frequency, rate or extent of osteoclast differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045670 UBERON:0003409 biolink:AnatomicalEntity gland of tongue Any of the mucous, serous, or mixed glands that empty their secretions onto the surface of the tongue. go-plus.json lingual gland|tongue gland http://purl.obolibrary.org/obo/UBERON_0003409 UBERON:0003408 biolink:AnatomicalEntity gland of digestive tract A gland that is part of a digestive tract [Automatically generated definition]. go-plus.json lower gastrointestinal tract gland|digestive tract gland|gut gland|gland of lower gastrointestinal tract|gland of digestive tract http://purl.obolibrary.org/obo/UBERON_0003408 UBERON:0003405 biolink:AnatomicalEntity lobar bronchus of left lung A lobar bronchus that is part of a left lung [Automatically generated definition]. go-plus.json left lung secondary bronchus|left lobar bronchus|secondary bronchus of left lung|left lung lobar bronchus http://purl.obolibrary.org/obo/UBERON_0003405 GO:0021620 biolink:BiologicalProcess hypoglossal nerve formation The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. go-plus.json CN XII biosynthesis|CN XII formation http://purl.obolibrary.org/obo/GO_0021620 UBERON:0003406 biolink:AnatomicalEntity cartilage of respiratory system A cartilage element that is part of a respiratory system [Automatically generated definition]. go-plus.json respiratory system cartilage|apparatus respiratorius cartilage|cartilage of apparatus respiratorius http://purl.obolibrary.org/obo/UBERON_0003406 GO:0021621 biolink:BiologicalProcess hypoglossal nerve structural organization The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. go-plus.json CN XII structural organization|hypoglossal nerve structural organisation http://purl.obolibrary.org/obo/GO_0021621 GO:0045677 biolink:BiologicalProcess negative regulation of R7 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation. go-plus.json down-regulation of R7 differentiation|downregulation of R7 differentiation|down regulation of R7 differentiation|inhibition of R7 differentiation|negative regulation of R7 differentiation http://purl.obolibrary.org/obo/GO_0045677 GO:0045678 biolink:BiologicalProcess positive regulation of R7 cell differentiation Any process that activates or increases the frequency, rate or extent of R7 cell differentiation. go-plus.json up regulation of R7 differentiation|upregulation of R7 differentiation|stimulation of R7 differentiation|up-regulation of R7 differentiation|positive regulation of R7 differentiation|activation of R7 differentiation http://purl.obolibrary.org/obo/GO_0045678 GO:0045675 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045675 GO:0045676 biolink:BiologicalProcess regulation of R7 cell differentiation Any process that modulates the frequency, rate or extent of R7 differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045676 GO:0045673 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045673 GO:0045674 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0045674 CHEBI:22263 biolink:ChemicalSubstance 5'-adenylyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22263 CHEBI:22260 biolink:ChemicalSubstance adenosines go-plus.json http://purl.obolibrary.org/obo/CHEBI_22260 GO:0045671 biolink:BiologicalProcess negative regulation of osteoclast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. go-plus.json down-regulation of osteoclast differentiation|downregulation of osteoclast differentiation|down regulation of osteoclast differentiation|inhibition of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045671 GO:0045672 biolink:BiologicalProcess positive regulation of osteoclast differentiation Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. go-plus.json up-regulation of osteoclast differentiation|activation of osteoclast differentiation|up regulation of osteoclast differentiation|upregulation of osteoclast differentiation|stimulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045672 GO:0070639 biolink:BiologicalProcess vitamin D2 metabolic process The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol. go-plus.json calciferol metabolic process|vitamin D2 metabolism|ergocalciferol metabolic process http://purl.obolibrary.org/obo/GO_0070639 GO:0070637 biolink:BiologicalProcess pyridine nucleoside metabolic process The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose. go-plus.json pyridine nucleoside metabolism http://purl.obolibrary.org/obo/GO_0070637 GO:0070638 biolink:BiologicalProcess pyridine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose. go-plus.json pyridine nucleoside degradation|pyridine nucleoside catabolism|pyridine nucleoside breakdown http://purl.obolibrary.org/obo/GO_0070638 GO:0045679 biolink:BiologicalProcess regulation of R8 cell differentiation Any process that modulates the frequency, rate or extent of R8 differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045679 GO:0070635 biolink:MolecularActivity nicotinamide riboside hydrolase activity Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose. MetaCyc:RXN-8441 go-plus.json N-ribosylnicotinamide hydrolase activity|nicotinamide ribonucleoside hydrolase activity http://purl.obolibrary.org/obo/GO_0070635 GO:0070636 biolink:MolecularActivity nicotinic acid riboside hydrolase activity Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose. go-plus.json nicotinic acid ribonucleoside hydrolase activity|nicotinate ribonucleoside hydrolase activity|D-ribosylnicotinic acid hydrolase activity|D-ribosylnicotinate hydrolase activity|nicotinate riboside hydrolase activity http://purl.obolibrary.org/obo/GO_0070636 GO:0070633 biolink:BiologicalProcess transepithelial transport The directed movement of a substance from one side of an epithelium to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0070633 GO:0021622 biolink:BiologicalProcess oculomotor nerve morphogenesis The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. go-plus.json CN III morphogenesis http://purl.obolibrary.org/obo/GO_0021622 GO:0070634 biolink:BiologicalProcess transepithelial ammonium transport The directed movement of ammonium ions from one side of an epithelium to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0070634 GO:0021623 biolink:BiologicalProcess oculomotor nerve formation The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. go-plus.json CN III formation|CN III biosynthesis http://purl.obolibrary.org/obo/GO_0021623 GO:0070631 biolink:BiologicalProcess spindle pole body localization Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells. go-plus.json maintenance of spindle pole body localization|spindle pole body localisation http://purl.obolibrary.org/obo/GO_0070631 GO:0021624 biolink:BiologicalProcess oculomotor nerve structural organization The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. go-plus.json CN III structural organization|oculomotor nerve structural organisation http://purl.obolibrary.org/obo/GO_0021624 UBERON:0003412 biolink:AnatomicalEntity pelvic appendage bud mesenchyme Mesenchyme that is part of a pelvic appendage bud. go-plus.json mesoderm pelvic fin bud|lower limb bud mesenchyme|leg mesenchyme|pelvic fin bud mesenchyme|hindlimb bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0003412 GO:0070632 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070632 UBERON:0003413 biolink:AnatomicalEntity pectoral appendage bud mesenchyme Mesenchyme that is part of a pectoral appendage bud. go-plus.json arm mesenchyme|forelimb bud mesenchyme|upper limb bud mesenchyme|mesoderm pectoral fin bud|wing mesenchyme|pectoral fin bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0003413 GO:0021625 biolink:BiologicalProcess oculomotor nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. go-plus.json CN III maturation http://purl.obolibrary.org/obo/GO_0021625 GO:0021626 biolink:BiologicalProcess central nervous system maturation A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. go-plus.json http://purl.obolibrary.org/obo/GO_0021626 GO:0070630 biolink:BiologicalProcess (1->4)-alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds. go-plus.json 1,4-alpha-glucan synthesis|alpha-1,4 glucan biosynthetic process|alpha-1,4 glucan biosynthesis|(1->4)-alpha-D-glucan biosynthesis|1,4-alpha-glucan formation|(1->4)-alpha-D-glucan anabolism|alpha-1,4 glucan anabolism|(1->4)-alpha-D-glucan synthesis|alpha-1,4 glucan synthesis|1,4-alpha-glucan biosynthesis|1,4-alpha-glucan biosynthetic process|(1->4)-alpha-D-glucan formation|alpha-1,4 glucan formation|1,4-alpha-glucan anabolism http://purl.obolibrary.org/obo/GO_0070630 CHEBI:71274 biolink:ChemicalSubstance mannooligosaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_71274 GO:0021627 biolink:BiologicalProcess olfactory nerve morphogenesis The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. go-plus.json CN I morphogenesis http://purl.obolibrary.org/obo/GO_0021627 GO:0021628 biolink:BiologicalProcess olfactory nerve formation The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. go-plus.json CN I formation|CN I biosynthesis http://purl.obolibrary.org/obo/GO_0021628 GO:0021629 biolink:BiologicalProcess olfactory nerve structural organization The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. go-plus.json CN I structural organization|olfactory nerve structural organisation http://purl.obolibrary.org/obo/GO_0021629 GO:0045680 biolink:BiologicalProcess negative regulation of R8 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation. go-plus.json negative regulation of R8 differentiation|down-regulation of R8 differentiation|downregulation of R8 differentiation|down regulation of R8 differentiation|inhibition of R8 differentiation http://purl.obolibrary.org/obo/GO_0045680 CHEBI:71288 biolink:ChemicalSubstance (1->3)-alpha-D-mannooligosaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_71288 GO:0045681 biolink:BiologicalProcess positive regulation of R8 cell differentiation Any process that activates or increases the frequency, rate or extent of R8 cell differentiation. go-plus.json stimulation of R8 differentiation|activation of R8 differentiation|up-regulation of R8 differentiation|positive regulation of R8 differentiation|up regulation of R8 differentiation|upregulation of R8 differentiation http://purl.obolibrary.org/obo/GO_0045681 CHEBI:22278 biolink:ChemicalSubstance alanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_22278 GO:0055007 biolink:BiologicalProcess cardiac muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. go-plus.json cardiomyocyte differentiation|heart muscle cell differentiation http://purl.obolibrary.org/obo/GO_0055007 GO:0055008 biolink:BiologicalProcess cardiac muscle tissue morphogenesis The process in which the anatomical structures of cardiac muscle tissue are generated and organized. go-plus.json myocardium morphogenesis|heart muscle morphogenesis http://purl.obolibrary.org/obo/GO_0055008 GO:0055009 biolink:BiologicalProcess atrial cardiac muscle tissue morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. go-plus.json cardiac atrium muscle morphogenesis|atrial myocardium morphogenesis|atrial heart muscle morphogenesis http://purl.obolibrary.org/obo/GO_0055009 GO:0021610 biolink:BiologicalProcess facial nerve morphogenesis The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. go-plus.json CN VII morphogenesis http://purl.obolibrary.org/obo/GO_0021610 CHEBI:46229 biolink:ChemicalSubstance UDP-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_46229 GO:0045688 biolink:BiologicalProcess regulation of antipodal cell differentiation Any process that modulates the frequency, rate or extent of antipodal cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045688 GO:0045689 biolink:BiologicalProcess negative regulation of antipodal cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation. go-plus.json down-regulation of antipodal cell differentiation|downregulation of antipodal cell differentiation|down regulation of antipodal cell differentiation|inhibition of antipodal cell differentiation http://purl.obolibrary.org/obo/GO_0045689 GO:0045686 biolink:BiologicalProcess negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. go-plus.json down-regulation of glial cell differentiation|downregulation of glial cell differentiation|negative regulation of glia cell differentiation|down regulation of glial cell differentiation|inhibition of glial cell differentiation|negative regulation of neuroglia differentiation http://purl.obolibrary.org/obo/GO_0045686 GO:0045687 biolink:BiologicalProcess positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. go-plus.json up regulation of glial cell differentiation|positive regulation of glia cell differentiation|upregulation of glial cell differentiation|positive regulation of neuroglia differentiation|stimulation of glial cell differentiation|activation of glial cell differentiation|up-regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045687 GO:0045684 biolink:BiologicalProcess positive regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermis development. go-plus.json upregulation of epidermis development|up regulation of epidermis development|positive regulation of epidermal development|activation of epidermis development|stimulation of epidermis development|positive regulation of hypodermis development|up-regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045684 GO:0045685 biolink:BiologicalProcess regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of glia cell differentiation. go-plus.json regulation of glia cell differentiation|regulation of neuroglia differentiation http://purl.obolibrary.org/obo/GO_0045685 GO:0045682 biolink:BiologicalProcess regulation of epidermis development Any process that modulates the frequency, rate or extent of epidermis development. go-plus.json regulation of hypodermis development|regulation of epidermal development http://purl.obolibrary.org/obo/GO_0045682 CHEBI:22271 biolink:ChemicalSubstance aflatoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22271 GO:0045683 biolink:BiologicalProcess negative regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. go-plus.json down regulation of epidermis development|downregulation of epidermis development|negative regulation of epidermal development|negative regulation of hypodermis development|down-regulation of epidermis development|inhibition of epidermis development http://purl.obolibrary.org/obo/GO_0045683 GO:0021619 biolink:BiologicalProcess hypoglossal nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. go-plus.json CN XII maturation http://purl.obolibrary.org/obo/GO_0021619 GO:0070628 biolink:MolecularActivity proteasome binding Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation. go-plus.json http://purl.obolibrary.org/obo/GO_0070628 goslim_chembl GO:0070629 biolink:BiologicalProcess (1->4)-alpha-glucan metabolic process The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds. go-plus.json 1,4-alpha-glucan metabolism|1,4-alpha-D-glucan metabolism|alpha-1,4 glucan metabolic process|alpha-1,4 glucan metabolism|(1->4)-alpha-D-glucan metabolism http://purl.obolibrary.org/obo/GO_0070629 GO:0070626 biolink:MolecularActivity (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. MetaCyc:AICARSYN-RXN|EC:4.3.2.2|KEGG_REACTION:R04559|RHEA:23920 go-plus.json succino AMP-lyase activity|adenylosuccinate lyase activity|adenylosuccinase activity http://purl.obolibrary.org/obo/GO_0070626 GO:0070627 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0070627 GO:0070624 biolink:BiologicalProcess negative regulation of thiamine biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. go-plus.json inhibition of thiamine biosynthetic process|negative regulation of thiamin biosynthetic process|down regulation of thiamine biosynthetic process|downregulation of thiamine biosynthetic process|negative regulation of thiamine anabolism|negative regulation of thiamine synthesis|down-regulation of thiamine biosynthetic process|negative regulation of thiamine biosynthesis|negative regulation of thiamine formation http://purl.obolibrary.org/obo/GO_0070624 GO:0070625 biolink:BiologicalProcess zymogen granule exocytosis The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions. go-plus.json http://purl.obolibrary.org/obo/GO_0070625 GO:0070622 biolink:CellularComponent UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits. go-plus.json UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex|N-acetylglucosamine-1-phosphotransferase complex http://purl.obolibrary.org/obo/GO_0070622 GO:0055003 biolink:BiologicalProcess cardiac myofibril assembly The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. go-plus.json heart myofibril assembly|cardiac myofibril morphogenesis|cardiac myofibril development http://purl.obolibrary.org/obo/GO_0055003 UBERON:0003403 biolink:AnatomicalEntity skin of forearm A zone of skin that is part of a lower arm [Automatically generated definition]. go-plus.json lower arm skin|lower segment of arm skin|forearm skin|skin of zeugopod of arm|skin of lower arm|skin of antebrachial region|skin of lower segment of arm http://purl.obolibrary.org/obo/UBERON_0003403 GO:0021611 biolink:BiologicalProcess facial nerve formation The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. go-plus.json CN VII formation|CN VII biosynthesis http://purl.obolibrary.org/obo/GO_0021611 GO:0070623 biolink:BiologicalProcess regulation of thiamine biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. go-plus.json regulation of thiamine anabolism|regulation of thiamine synthesis|regulation of thiamine formation|regulation of thiamin biosynthetic process|regulation of thiamine biosynthesis http://purl.obolibrary.org/obo/GO_0070623 GO:0021612 biolink:BiologicalProcess facial nerve structural organization The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. go-plus.json CN VII structural organization|facial nerve structural organisation http://purl.obolibrary.org/obo/GO_0021612 UBERON:0003404 biolink:AnatomicalEntity lobar bronchus of right lung A lobar bronchus that is part of a right lung [Automatically generated definition]. go-plus.json right lung lobar bronchus|right lung secondary bronchus|secondary bronchus of right lung|right lobar bronchus http://purl.obolibrary.org/obo/UBERON_0003404 GO:0055004 biolink:BiologicalProcess atrial cardiac myofibril assembly The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. go-plus.json atrial cardiac myofibril development|atrial heart myofibril development http://purl.obolibrary.org/obo/GO_0055004 GO:0070620 biolink:CellularComponent EGFR-Grb2-Sos complex A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. go-plus.json Egfr-Grb2-mSos1 complex, EGF stimulated http://purl.obolibrary.org/obo/GO_0070620 GO:0055005 biolink:BiologicalProcess ventricular cardiac myofibril assembly The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. go-plus.json ventricular cardiac myofibril development|ventricular heart myofibril development http://purl.obolibrary.org/obo/GO_0055005 GO:0021613 biolink:BiologicalProcess facial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. go-plus.json CN VII maturation http://purl.obolibrary.org/obo/GO_0021613 GO:0021614 biolink:BiologicalProcess glossopharyngeal nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. go-plus.json CN IX maturation http://purl.obolibrary.org/obo/GO_0021614 GO:0070621 biolink:CellularComponent EGFR-Shc-Grb2-Sos complex A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0070621 GO:0055006 biolink:BiologicalProcess cardiac cell development The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. go-plus.json cardiocyte development|heart cell development http://purl.obolibrary.org/obo/GO_0055006 GO:0021615 biolink:BiologicalProcess glossopharyngeal nerve morphogenesis The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. go-plus.json CN IX morphogenesis http://purl.obolibrary.org/obo/GO_0021615 GO:0021616 biolink:BiologicalProcess glossopharyngeal nerve formation The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. go-plus.json CN IX formation|CN IX biosynthesis http://purl.obolibrary.org/obo/GO_0021616 CHEBI:71285 biolink:ChemicalSubstance organophosphonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71285 GO:0055001 biolink:BiologicalProcess muscle cell development The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. go-plus.json myofibre development|myofiber development|muscle fibre development|muscle fiber development http://purl.obolibrary.org/obo/GO_0055001 GO:0021617 biolink:BiologicalProcess glossopharyngeal nerve structural organization The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. go-plus.json CN IX structural organization|glossopharyngeal nerve structural organisation http://purl.obolibrary.org/obo/GO_0021617 CHEBI:71286 biolink:ChemicalSubstance 3-nitrotyramine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_71286 chebi_ph7_3 CHEBI:71287 biolink:ChemicalSubstance 4-hydroxy-3-nitrophenylacetaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71287 chebi_ph7_3 GO:0021618 biolink:BiologicalProcess hypoglossal nerve morphogenesis The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. go-plus.json CN XII morphogenesis http://purl.obolibrary.org/obo/GO_0021618 GO:0055002 biolink:BiologicalProcess striated muscle cell development The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0055002 GO:0045691 biolink:BiologicalProcess regulation of embryo sac central cell differentiation Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation. go-plus.json regulation of female gametophyte central cell differentiation http://purl.obolibrary.org/obo/GO_0045691 GO:0045692 biolink:BiologicalProcess negative regulation of embryo sac central cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation. go-plus.json down-regulation of female gametophyte central cell differentiation|negative regulation of female gametophyte central cell differentiation|inhibition of female gametophyte central cell differentiation|down regulation of female gametophyte central cell differentiation|downregulation of female gametophyte central cell differentiation http://purl.obolibrary.org/obo/GO_0045692 GO:0045690 biolink:BiologicalProcess positive regulation of antipodal cell differentiation Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation. go-plus.json stimulation of antipodal cell differentiation|up-regulation of antipodal cell differentiation|activation of antipodal cell differentiation|up regulation of antipodal cell differentiation|upregulation of antipodal cell differentiation http://purl.obolibrary.org/obo/GO_0045690 CHEBI:356010 biolink:ChemicalSubstance 5-aminopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_356010 chebi_ph7_3 GO:0055018 biolink:BiologicalProcess regulation of cardiac muscle fiber development Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. go-plus.json regulation of cardiac muscle fibre development|regulation of heart muscle fiber development http://purl.obolibrary.org/obo/GO_0055018 GO:0055019 biolink:BiologicalProcess negative regulation of cardiac muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. go-plus.json down-regulation of cardiac muscle fiber development|downregulation of cardiac muscle fiber development|down regulation of cardiac muscle fiber development|inhibition of cardiac muscle fiber development|negative regulation of heart muscle fiber development|negative regulation of cardiac muscle fibre development http://purl.obolibrary.org/obo/GO_0055019 GO:0045699 biolink:BiologicalProcess positive regulation of synergid differentiation Any process that activates or increases the frequency, rate or extent of synergid cell differentiation. go-plus.json up regulation of synergid differentiation|positive regulation of synergid cell differentiation|upregulation of synergid differentiation|stimulation of synergid differentiation|up-regulation of synergid differentiation|activation of synergid differentiation http://purl.obolibrary.org/obo/GO_0045699 GO:0045697 biolink:BiologicalProcess regulation of synergid differentiation Any process that modulates the frequency, rate or extent of synergid cell differentiation. go-plus.json regulation of synergid cell differentiation http://purl.obolibrary.org/obo/GO_0045697 GO:0045698 biolink:BiologicalProcess negative regulation of synergid differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation. go-plus.json downregulation of synergid differentiation|down regulation of synergid differentiation|inhibition of synergid differentiation|negative regulation of synergid cell differentiation|down-regulation of synergid differentiation http://purl.obolibrary.org/obo/GO_0045698 GO:0045695 biolink:BiologicalProcess negative regulation of embryo sac egg cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation. go-plus.json down regulation of female gametophyte egg cell differentiation|downregulation of female gametophyte egg cell differentiation|down-regulation of female gametophyte egg cell differentiation|negative regulation of female gametophyte egg cell differentiation|inhibition of female gametophyte egg cell differentiation http://purl.obolibrary.org/obo/GO_0045695 GO:0045696 biolink:BiologicalProcess positive regulation of embryo sac egg cell differentiation Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation. go-plus.json upregulation of female gametophyte egg cell differentiation|up regulation of female gametophyte egg cell differentiation|activation of female gametophyte egg cell differentiation|positive regulation of female gametophyte egg cell differentiation|stimulation of female gametophyte egg cell differentiation|up-regulation of female gametophyte egg cell differentiation http://purl.obolibrary.org/obo/GO_0045696 GO:0045693 biolink:BiologicalProcess positive regulation of embryo sac central cell differentiation Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation. go-plus.json positive regulation of female gametophyte central cell differentiation|stimulation of female gametophyte central cell differentiation|up-regulation of female gametophyte central cell differentiation|upregulation of female gametophyte central cell differentiation|up regulation of female gametophyte central cell differentiation|activation of female gametophyte central cell differentiation http://purl.obolibrary.org/obo/GO_0045693 GO:0045694 biolink:BiologicalProcess regulation of embryo sac egg cell differentiation Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation. go-plus.json regulation of female gametophyte egg cell differentiation http://purl.obolibrary.org/obo/GO_0045694 GO:0021608 biolink:BiologicalProcess accessory nerve formation The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. go-plus.json CN XI biosynthesis|CN XI formation http://purl.obolibrary.org/obo/GO_0021608 CHEBI:36885 biolink:ChemicalSubstance 20-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36885 GO:0021609 biolink:BiologicalProcess accessory nerve structural organization The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. go-plus.json CN XI structural organization|accessory nerve structural organisation http://purl.obolibrary.org/obo/GO_0021609 CHEBI:36886 biolink:ChemicalSubstance 21-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36886 CHEBI:36883 biolink:ChemicalSubstance 6-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36883 CHEBI:36884 biolink:ChemicalSubstance 26-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36884 GO:0070659 biolink:BiologicalProcess inner ear sensory epithelium regeneration The regrowth of lost or destroyed inner ear sensory epithelia. go-plus.json http://purl.obolibrary.org/obo/GO_0070659 GO:0070657 biolink:BiologicalProcess neuromast regeneration The regrowth of a neuromast following its loss or destruction. go-plus.json http://purl.obolibrary.org/obo/GO_0070657 CHEBI:36887 biolink:ChemicalSubstance 18-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36887 GO:0070658 biolink:BiologicalProcess neuromast hair cell differentiation involved in neuromast regeneration Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury. go-plus.json http://purl.obolibrary.org/obo/GO_0070658 GO:0055014 biolink:BiologicalProcess atrial cardiac muscle cell development The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. go-plus.json atrial heart muscle development|atrial cardiomyocyte development http://purl.obolibrary.org/obo/GO_0055014 GO:0070655 biolink:BiologicalProcess mechanosensory epithelium regeneration The regrowth of lost or destroyed mechanosensory epithelia. go-plus.json http://purl.obolibrary.org/obo/GO_0070655 GO:0021600 biolink:BiologicalProcess abducens nerve structural organization The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. go-plus.json abducens nerve structural organisation|CN VI structural organization http://purl.obolibrary.org/obo/GO_0021600 GO:0021601 biolink:BiologicalProcess abducens nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. go-plus.json CN VI maturation http://purl.obolibrary.org/obo/GO_0021601 GO:0070656 biolink:BiologicalProcess mechanoreceptor differentiation involved in mechanosensory epithelium regeneration Differentiation of new mechanoreceptors to replace those lost or destroyed by injury. go-plus.json http://purl.obolibrary.org/obo/GO_0070656 GO:0055015 biolink:BiologicalProcess ventricular cardiac muscle cell development The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ. go-plus.json ventricular heart muscle cell development|ventricular cardiomyocyte development http://purl.obolibrary.org/obo/GO_0055015 CHEBI:71293 biolink:ChemicalSubstance homopolysaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_71293 GO:0070653 biolink:MolecularActivity high-density lipoprotein particle receptor binding Binding to a high-density lipoprotein receptor. go-plus.json high-density lipoprotein receptor binding|HDL receptor binding http://purl.obolibrary.org/obo/GO_0070653 GO:0055016 biolink:BiologicalProcess hypochord development The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta. go-plus.json subnotochordal rod development http://purl.obolibrary.org/obo/GO_0055016 GO:0021602 biolink:BiologicalProcess cranial nerve morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. go-plus.json http://purl.obolibrary.org/obo/GO_0021602 GO:0055017 biolink:BiologicalProcess cardiac muscle tissue growth The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. go-plus.json heart muscle growth http://purl.obolibrary.org/obo/GO_0055017 GO:0070654 biolink:BiologicalProcess sensory epithelium regeneration The regrowth of a sensory epithelium following its loss or destruction. go-plus.json http://purl.obolibrary.org/obo/GO_0070654 GO:0021603 biolink:BiologicalProcess cranial nerve formation The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. go-plus.json http://purl.obolibrary.org/obo/GO_0021603 GO:0070651 biolink:BiologicalProcess nonfunctional rRNA decay An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system. go-plus.json NRD http://purl.obolibrary.org/obo/GO_0070651 GO:0055010 biolink:BiologicalProcess ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. go-plus.json ventricular heart muscle morphogenesis|cardiac ventricle muscle morphogenesis http://purl.obolibrary.org/obo/GO_0055010 GO:0021604 biolink:BiologicalProcess cranial nerve structural organization The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. go-plus.json cranial nerve structural organisation http://purl.obolibrary.org/obo/GO_0021604 GO:0055011 biolink:BiologicalProcess atrial cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. go-plus.json atrial heart muscle cell differentiation|atrial cardiomyocyte differentiation http://purl.obolibrary.org/obo/GO_0055011 GO:0070652 biolink:CellularComponent HAUS complex A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex. go-plus.json HAUS augmin complex http://purl.obolibrary.org/obo/GO_0070652 GO:0021605 biolink:BiologicalProcess cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. go-plus.json http://purl.obolibrary.org/obo/GO_0021605 CHEBI:71296 biolink:ChemicalSubstance fructan derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_71296 CHEBI:36882 biolink:ChemicalSubstance (3S)-citramalyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_36882 GO:0021606 biolink:BiologicalProcess accessory nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. go-plus.json CN XI maturation|spinal accessory nerve maturation http://purl.obolibrary.org/obo/GO_0021606 GO:0055012 biolink:BiologicalProcess ventricular cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ. go-plus.json ventricular cardiomyocyte differentiation|ventricular heart muscle cell differentiation http://purl.obolibrary.org/obo/GO_0055012 GO:0021607 biolink:BiologicalProcess accessory nerve morphogenesis The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. go-plus.json CN XI morphogenesis http://purl.obolibrary.org/obo/GO_0021607 GO:0055013 biolink:BiologicalProcess cardiac muscle cell development The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. go-plus.json heart muscle cell development|heart muscle fiber development|cardiomyocyte cell development|cardiac muscle fibre development|cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_0055013 GO:0070650 biolink:BiologicalProcess actin filament bundle distribution Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0070650 CHEBI:71298 biolink:ChemicalSubstance glucan derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_71298 CHEBI:36880 biolink:ChemicalSubstance organic radical ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36880 CHEBI:22256 biolink:ChemicalSubstance adenosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22256 GO:0055029 biolink:CellularComponent nuclear DNA-directed RNA polymerase complex A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0055029 OBO:GOCHE_37527 biolink:OntologyClass substance with acid role go-plus.json http://purl.obolibrary.org/obo/GOCHE_37527 3_STAR CHEBI:22251 biolink:ChemicalSubstance adenosine bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22251 CHEBI:36896 biolink:ChemicalSubstance monoatomic bromine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36896 CHEBI:36897 biolink:ChemicalSubstance monoatomic iodine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36897 CHEBI:36894 biolink:ChemicalSubstance elemental bromine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36894 GO:0055020 biolink:BiologicalProcess positive regulation of cardiac muscle fiber development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. go-plus.json stimulation of cardiac muscle fiber development|up-regulation of cardiac muscle fiber development|activation of cardiac muscle fiber development|positive regulation of cardiac muscle fibre development|up regulation of cardiac muscle fiber development|positive regulation of heart muscle fiber development|upregulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_0055020 CHEBI:36895 biolink:ChemicalSubstance monoatomic fluorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36895 GO:0070648 biolink:CellularComponent formin-nucleated actin cable An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth. go-plus.json http://purl.obolibrary.org/obo/GO_0070648 GO:0070649 biolink:BiologicalProcess formin-nucleated actin cable assembly The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. go-plus.json formin-nucleated actin cable formation http://purl.obolibrary.org/obo/GO_0070649 GO:0070646 biolink:BiologicalProcess protein modification by small protein removal A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070646 GO:0070647 biolink:BiologicalProcess protein modification by small protein conjugation or removal A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0070647 goslim_drosophila|goslim_pombe|goslim_yeast GO:0055025 biolink:BiologicalProcess positive regulation of cardiac muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. go-plus.json up regulation of cardiac muscle development|positive regulation of heart muscle development|upregulation of cardiac muscle development|stimulation of cardiac muscle development|up-regulation of cardiac muscle development|activation of cardiac muscle development http://purl.obolibrary.org/obo/GO_0055025 GO:0070644 biolink:MolecularActivity vitamin D response element binding Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum. go-plus.json VDRE binding http://purl.obolibrary.org/obo/GO_0070644 GO:0055026 biolink:BiologicalProcess negative regulation of cardiac muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. go-plus.json downregulation of cardiac muscle development|negative regulation of heart muscle development|down regulation of cardiac muscle development|inhibition of cardiac muscle development|down-regulation of cardiac muscle development http://purl.obolibrary.org/obo/GO_0055026 GO:0070645 biolink:CellularComponent Ubisch body A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development. go-plus.json orbicule http://purl.obolibrary.org/obo/GO_0070645 CHEBI:46209 biolink:ChemicalSubstance L-tyrosinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_46209 GO:0070642 biolink:BiologicalProcess vitamin D5 metabolic process The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol. go-plus.json vitamin D5 metabolism http://purl.obolibrary.org/obo/GO_0070642 GO:0055027 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0055027 GO:0070643 biolink:MolecularActivity vitamin D 25-hydroxylase activity Catalysis of the hydroxylation of C-25 of any form of vitamin D. go-plus.json cholecalciferol 25-hydroxylase activity|vitamin D2 25-hydroxylase activity|calciferol 25-hydroxylase activity|ergocalciferol 25-hydroxylase activity http://purl.obolibrary.org/obo/GO_0070643 GO:0055028 biolink:CellularComponent cortical microtubule Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0055028 GO:0070640 biolink:BiologicalProcess vitamin D3 metabolic process The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol. go-plus.json cholecalciferol metabolic process|calciol metabolic process|vitamin D3 metabolism http://purl.obolibrary.org/obo/GO_0070640 CHEBI:36892 biolink:ChemicalSubstance elemental fluorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36892 GO:0055021 biolink:BiologicalProcess regulation of cardiac muscle tissue growth Any process that modulates the frequency, rate or extent of cardiac muscle growth. go-plus.json http://purl.obolibrary.org/obo/GO_0055021 GO:0055022 biolink:BiologicalProcess negative regulation of cardiac muscle tissue growth Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. go-plus.json down regulation of cardiac muscle growth|downregulation of cardiac muscle growth|negative regulation of heart muscle growth|down-regulation of cardiac muscle growth|inhibition of cardiac muscle growth http://purl.obolibrary.org/obo/GO_0055022 GO:0070641 biolink:BiologicalProcess vitamin D4 metabolic process The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol. go-plus.json vitamin D4 metabolism http://purl.obolibrary.org/obo/GO_0070641 CHEBI:36893 biolink:ChemicalSubstance elemental iodine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36893 GO:0055023 biolink:BiologicalProcess positive regulation of cardiac muscle tissue growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. go-plus.json upregulation of cardiac muscle growth|positive regulation of heart muscle growth|up regulation of cardiac muscle growth|activation of cardiac muscle growth|stimulation of cardiac muscle growth|up-regulation of cardiac muscle growth http://purl.obolibrary.org/obo/GO_0055023 GO:0055024 biolink:BiologicalProcess regulation of cardiac muscle tissue development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. go-plus.json regulation of heart muscle development http://purl.obolibrary.org/obo/GO_0055024 CHEBI:36891 biolink:ChemicalSubstance diatomic iodine go-plus.json http://purl.obolibrary.org/obo/CHEBI_36891 GO:0031061 biolink:BiologicalProcess negative regulation of histone methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones. go-plus.json down-regulation of histone methylation|inhibition of histone methylation|down regulation of histone methylation|downregulation of histone methylation http://purl.obolibrary.org/obo/GO_0031061 GO:0031062 biolink:BiologicalProcess positive regulation of histone methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones. go-plus.json up regulation of histone methylation|activation of histone methylation|stimulation of histone methylation|up-regulation of histone methylation|upregulation of histone methylation http://purl.obolibrary.org/obo/GO_0031062 CHEBI:85800 biolink:ChemicalSubstance (R)-(2-chloro-5-oxo-2,5-dihydro-2-furyl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85800 GO:0031060 biolink:BiologicalProcess regulation of histone methylation Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones. go-plus.json http://purl.obolibrary.org/obo/GO_0031060 CHEBI:85801 biolink:ChemicalSubstance heparosan D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85801 CHEBI:85802 biolink:ChemicalSubstance heparosan L-iduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85802 CHEBI:85803 biolink:ChemicalSubstance (R)-ethylmalonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_85803 CHEBI:85804 biolink:ChemicalSubstance UDP-4-dehydro-6-deoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_85804 CHEBI:85805 biolink:ChemicalSubstance D-glucaro-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_85805 GO:0031069 biolink:BiologicalProcess hair follicle morphogenesis The process in which the anatomical structures of the hair follicle are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0031069 CHEBI:85806 biolink:ChemicalSubstance N,1-dipalmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85806 GO:0031067 biolink:BiologicalProcess negative regulation of histone deacetylation at centromere Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA. go-plus.json down regulation of histone deacetylation at centromere|downregulation of histone deacetylation at centromere|down-regulation of histone deacetylation at centromere|inhibition of histone deacetylation at centromere http://purl.obolibrary.org/obo/GO_0031067 CHEBI:85808 biolink:ChemicalSubstance N,1-dipalmitoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_85808 GO:0031068 biolink:BiologicalProcess positive regulation of histone deacetylation at centromere Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA. go-plus.json upregulation of histone deacetylation at centromere|up regulation of histone deacetylation at centromere|activation of histone deacetylation at centromere|stimulation of histone deacetylation at centromere|up-regulation of histone deacetylation at centromere http://purl.obolibrary.org/obo/GO_0031068 GO:0031065 biolink:BiologicalProcess positive regulation of histone deacetylation Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones. go-plus.json upregulation of histone deacetylation|up regulation of histone deacetylation|activation of histone deacetylation|stimulation of histone deacetylation|up-regulation of histone deacetylation http://purl.obolibrary.org/obo/GO_0031065 CHEBI:85809 biolink:ChemicalSubstance 5alpha-androstane-3beta,6alpha,17beta-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85809 chebi_ph7_3 GO:0031066 biolink:BiologicalProcess regulation of histone deacetylation at centromere Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0031066 GO:0031063 biolink:BiologicalProcess regulation of histone deacetylation Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones. go-plus.json http://purl.obolibrary.org/obo/GO_0031063 GO:0031064 biolink:BiologicalProcess negative regulation of histone deacetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones. go-plus.json down regulation of histone deacetylation|downregulation of histone deacetylation|down-regulation of histone deacetylation|inhibition of histone deacetylation http://purl.obolibrary.org/obo/GO_0031064 RO:0040036 biolink:OntologyClass has anatomical participant p has anatomical participant c iff p has participant c, and c is an anatomical entity RO:0040036 go-plus.json http://purl.obolibrary.org/obo/RO_0040036 GO:0031050 biolink:BiologicalProcess dsRNA processing Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function. go-plus.json dsRNA fragmentation|double-stranded RNA fragmentation http://purl.obolibrary.org/obo/GO_0031050 GO:0031051 biolink:BiologicalProcess scnRNA processing Cleavage of noncoding, double-stranded RNAs transcribed from the micronuclear genome to produce scnRNAs, small RNAs (~28 nucleotides) that direct the deletion of micronuclear-limited sequences from the developing macronuclear genome. go-plus.json scnRNA production http://purl.obolibrary.org/obo/GO_0031051 GO:0031058 biolink:BiologicalProcess positive regulation of histone modification Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone. go-plus.json up regulation of histone modification|upregulation of histone modification|stimulation of histone modification|up-regulation of histone modification|activation of histone modification http://purl.obolibrary.org/obo/GO_0031058 GO:0031059 biolink:BiologicalProcess histone deacetylation at centromere The removal of acetyl groups from histones in centromeric DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0031059 GO:0031056 biolink:BiologicalProcess regulation of histone modification Any process that modulates the frequency, rate or extent of the covalent alteration of a histone. go-plus.json http://purl.obolibrary.org/obo/GO_0031056 GO:0031057 biolink:BiologicalProcess negative regulation of histone modification Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone. go-plus.json down-regulation of histone modification|downregulation of histone modification|down regulation of histone modification|inhibition of histone modification http://purl.obolibrary.org/obo/GO_0031057 GO:0031054 biolink:BiologicalProcess pre-miRNA processing Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule. go-plus.json pre-microRNA processing http://purl.obolibrary.org/obo/GO_0031054 GO:0031055 biolink:BiologicalProcess chromatin remodeling at centromere Dynamic structural changes in centromeric DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0031055 GO:0031052 biolink:BiologicalProcess chromosome breakage Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage. go-plus.json establishment or maintenance of heterochromatin architecture http://purl.obolibrary.org/obo/GO_0031052 GO:0031053 biolink:BiologicalProcess primary miRNA processing Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule. go-plus.json primary microRNA processing|pri-miRNA processing http://purl.obolibrary.org/obo/GO_0031053 GO:0031049 biolink:BiologicalProcess programmed DNA elimination The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate. go-plus.json http://purl.obolibrary.org/obo/GO_0031049 goslim_pir CHEBI:141588 biolink:ChemicalSubstance phosphatidylethanolamine 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_141588 GO:0006089 biolink:BiologicalProcess lactate metabolic process The chemical reactions and pathways involving lactate, the anion of lactic acid. go-plus.json 2-hydroxypropanoate metabolism|lactate metabolism|alpha-hydroxypropionate metabolism|alpha-hydroxypropionate metabolic process|2-hydroxypropanoate metabolic process http://purl.obolibrary.org/obo/GO_0006089 GO:0006087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006087 GO:0006088 biolink:BiologicalProcess obsolete acetate to acetyl-CoA OBSOLETE. (Was not defined before being made obsolete). go-plus.json acetate to acetyl-CoA http://purl.obolibrary.org/obo/GO_0006088 GO:0006085 biolink:BiologicalProcess acetyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. MetaCyc:PWY-5173 go-plus.json acetyl-CoA formation|acetyl-CoA anabolism|acetyl-CoA biosynthesis|acetyl-CoA synthesis http://purl.obolibrary.org/obo/GO_0006085 GO:0006086 biolink:BiologicalProcess acetyl-CoA biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. MetaCyc:PYRUVDEHYD-PWY go-plus.json acetyl-CoA synthesis from pyruvate|acetyl-CoA formation from pyruvate|pyruvate dehydrogenase pathway|acetyl-CoA anabolism from pyruvate http://purl.obolibrary.org/obo/GO_0006086 GO:0006094 biolink:BiologicalProcess gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. Wikipedia:Gluconeogenesis|MetaCyc:GLUCONEO-PWY go-plus.json glucose biosynthesis|glucose biosynthetic process http://purl.obolibrary.org/obo/GO_0006094 GO:0031040 biolink:CellularComponent micronucleus A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell. Wikipedia:Micronucleus go-plus.json http://purl.obolibrary.org/obo/GO_0031040 CHEBI:85820 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85820 GO:0006095 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006095 GO:0006092 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006092 GO:0006093 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0006093 GO:0006090 biolink:BiologicalProcess pyruvate metabolic process The chemical reactions and pathways involving pyruvate, 2-oxopropanoate. MetaCyc:P41-PWY|Wikipedia:Pyruvic_acid go-plus.json pyruvate dehydrogenase bypass|pyruvate metabolism http://purl.obolibrary.org/obo/GO_0006090 GO:0006091 biolink:BiologicalProcess generation of precursor metabolites and energy The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. go-plus.json metabolic energy generation|energy pathways|intermediary metabolism http://purl.obolibrary.org/obo/GO_0006091 goslim_plant|goslim_pir|goslim_drosophila|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast|goslim_candida GO:0031047 biolink:BiologicalProcess gene silencing by RNA Any process in which RNA molecules inactivate expression of target genes. go-plus.json RNA-mediated gene silencing http://purl.obolibrary.org/obo/GO_0031047 GO:0031048 biolink:BiologicalProcess heterochromatin assembly by small RNA Assembly of heterochromatin, directed by small RNAs sharing sequence identity to the repressed region. go-plus.json RNA-mediated TGS|RNA interference-like chromatin silencing|RNA-mediated chromatin silencing|RNAi-directed chromatin silencing|RNAi-like chromatin silencing|chromatin silencing by small RNA|small RNA-mediated heterochromatic silencing|heterochromatin formation involved in chromatin silencing by small RNA|RNA-mediated transcriptional silencing|small RNA-mediated heterochromatin formation|heterochromatin assembly involved in chromatin silencing by small RNA http://purl.obolibrary.org/obo/GO_0031048 GO:0031045 biolink:CellularComponent dense core granule Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted. NIF_Subcellular:sao772007592 go-plus.json dense core vesicle http://purl.obolibrary.org/obo/GO_0031045 CHEBI:85829 biolink:ChemicalSubstance CDP-1-stearoyl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85829 GO:0031046 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031046 GO:0031043 biolink:BiologicalProcess O-glycan processing, core 7 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0031043 GO:0031044 biolink:BiologicalProcess O-glycan processing, core 8 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0031044 GO:0031041 biolink:BiologicalProcess O-glycan processing, core 5 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0031041 GO:0031042 biolink:BiologicalProcess O-glycan processing, core 6 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc. go-plus.json http://purl.obolibrary.org/obo/GO_0031042 GO:0031038 biolink:BiologicalProcess myosin II filament organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules. go-plus.json myosin II polymerization or depolymerization|myosin II filament assembly or disassembly|myosin II filament organisation http://purl.obolibrary.org/obo/GO_0031038 GO:0031039 biolink:CellularComponent macronucleus A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell. Wikipedia:Macronucleus go-plus.json http://purl.obolibrary.org/obo/GO_0031039 GO:0006098 biolink:BiologicalProcess pentose-phosphate shunt The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate). MetaCyc:PENTOSE-P-PWY|KEGG_PATHWAY:00030|Reactome:R-HSA-71336|Wikipedia:Pentose_phosphate_pathway go-plus.json pentose phosphate pathway|hexose monophosphate pathway|pentose phosphate shunt|pentose-phosphate pathway http://purl.obolibrary.org/obo/GO_0006098 GO:0006099 biolink:BiologicalProcess tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. MetaCyc:P42-PWY|MetaCyc:TCA|MetaCyc:P105-PWY|Wikipedia:Tricarboxylic_acid_cycle go-plus.json citric acid cycle|TCA cycle|Krebs cycle http://purl.obolibrary.org/obo/GO_0006099 GO:0006096 biolink:BiologicalProcess glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. MetaCyc:GLYCOLYSIS-VARIANTS go-plus.json Embden-Meyerhof-Parnas pathway|glycolysis|anaerobic glycolysis|Embden-Meyerhof pathway|modifed Embden-Meyerhof pathway http://purl.obolibrary.org/obo/GO_0006096 GO:0006097 biolink:BiologicalProcess glyoxylate cycle A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate. Wikipedia:Glyoxylate_cycle|MetaCyc:GLYOXYLATE-BYPASS go-plus.json glyoxylate bypass http://purl.obolibrary.org/obo/GO_0006097 CHEBI:85810 biolink:ChemicalSubstance androst-5-ene-3beta,7alpha,17beta-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85810 chebi_ph7_3 CHEBI:85811 biolink:ChemicalSubstance (6S)-5,6,7,8-tetrahydropteroic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_85811 CHEBI:85812 biolink:ChemicalSubstance Cer(d42:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_85812 chebi_ph7_3 CHEBI:85816 biolink:ChemicalSubstance (3beta,5alpha,7alpha)-3,7-dihydroxyandrostan-17-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_85816 chebi_ph7_3 GO:0031036 biolink:BiologicalProcess myosin II filament assembly The formation of a bipolar filament composed of myosin II molecules. go-plus.json myosin II polymerization http://purl.obolibrary.org/obo/GO_0031036 GO:0031037 biolink:BiologicalProcess myosin II filament disassembly The disassembly of a bipolar filament composed of myosin II molecules. go-plus.json myosin II depolymerization http://purl.obolibrary.org/obo/GO_0031037 GO:0031034 biolink:BiologicalProcess myosin filament assembly The aggregation, arrangement and bonding together of a filament composed of myosin molecules. go-plus.json myosin polymerization http://purl.obolibrary.org/obo/GO_0031034 GO:0031035 biolink:BiologicalProcess myosin filament disassembly The disassembly of a filament composed of myosin molecules. go-plus.json myosin depolymerization http://purl.obolibrary.org/obo/GO_0031035 GO:0031032 biolink:BiologicalProcess actomyosin structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. go-plus.json actomyosin structure organisation|actomyosin structure organization and biogenesis|actomyosin organization http://purl.obolibrary.org/obo/GO_0031032 GO:0031033 biolink:BiologicalProcess myosin filament organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules. go-plus.json myosin filament organisation|myosin polymerization or depolymerization|myosin filament assembly or disassembly http://purl.obolibrary.org/obo/GO_0031033 GO:0031030 biolink:BiologicalProcess negative regulation of septation initiation signaling Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling. go-plus.json down-regulation of septation initiation signaling|downregulation of septation initiation signaling|negative regulation of septation initiation network|down regulation of septation initiation signaling|inhibition of septation initiation signaling|negative regulation of septation initiation signalling|negative regulation of septation initiation signaling cascade http://purl.obolibrary.org/obo/GO_0031030 GO:0031031 biolink:BiologicalProcess positive regulation of septation initiation signaling Any process that activates or increases the frequency, rate or extent of septation initiation signaling. go-plus.json positive regulation of septation initiation signaling cascade|up regulation of septation initiation signaling|positive regulation of septation initiation signalling|upregulation of septation initiation signaling|positive regulation of septation initiation network|stimulation of septation initiation signaling|up-regulation of septation initiation signaling|activation of septation initiation signaling http://purl.obolibrary.org/obo/GO_0031031 GO:0031029 biolink:BiologicalProcess regulation of septation initiation signaling Any process that modulates the frequency, rate or extent of septation initiation signaling. go-plus.json regulation of septation initiation signaling cascade|regulation of septation initiation signalling|regulation of septation initiation network http://purl.obolibrary.org/obo/GO_0031029 GO:0031027 biolink:CellularComponent glutamate synthase complex (NADH) A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity. go-plus.json http://purl.obolibrary.org/obo/GO_0031027 GO:0031028 biolink:BiologicalProcess septation initiation signaling The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis. go-plus.json septation initiation network|septation initiation signalling|septation initiation signaling cascade|SIN http://purl.obolibrary.org/obo/GO_0031028 GO:0006069 biolink:BiologicalProcess ethanol oxidation An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate. go-plus.json http://purl.obolibrary.org/obo/GO_0006069 GO:0006067 biolink:BiologicalProcess ethanol metabolic process The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. go-plus.json ethanol metabolism http://purl.obolibrary.org/obo/GO_0006067 GO:0006068 biolink:BiologicalProcess ethanol catabolic process The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. go-plus.json ethanol catabolism|ethanol degradation|ethanol breakdown http://purl.obolibrary.org/obo/GO_0006068 CHEBI:61870 biolink:ChemicalSubstance monounsaturated fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_61870 GO:0006065 biolink:BiologicalProcess UDP-glucuronate biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-4841 go-plus.json UDP-glucuronate biosynthesis|UDP-glucuronate anabolism|UDP-glucuronate synthesis|UDP-glucuronate formation http://purl.obolibrary.org/obo/GO_0006065 GO:0006066 biolink:BiologicalProcess alcohol metabolic process The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. go-plus.json alcohol metabolism http://purl.obolibrary.org/obo/GO_0006066 goslim_pir|goslim_drosophila GO:0006063 biolink:BiologicalProcess uronic acid metabolic process The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose. go-plus.json uronic acid metabolism http://purl.obolibrary.org/obo/GO_0006063 GO:0006064 biolink:BiologicalProcess glucuronate catabolic process The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid. go-plus.json glucuronate catabolism|glucuronate degradation|glucuronate breakdown http://purl.obolibrary.org/obo/GO_0006064 CHEBI:85841 biolink:ChemicalSubstance CDP-1-stearoyl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85841 GO:0006072 biolink:BiologicalProcess glycerol-3-phosphate metabolic process The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol. go-plus.json glycerol-3-phosphate metabolism http://purl.obolibrary.org/obo/GO_0006072 GO:0006073 biolink:BiologicalProcess cellular glucan metabolic process The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell. go-plus.json cellular glucan metabolism http://purl.obolibrary.org/obo/GO_0006073 GO:0006070 biolink:BiologicalProcess octanol metabolic process The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH. go-plus.json octanol metabolism http://purl.obolibrary.org/obo/GO_0006070 GO:0006071 biolink:BiologicalProcess glycerol metabolic process The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. MetaCyc:GLYCEROLMETAB-PWY go-plus.json glycerol metabolism http://purl.obolibrary.org/obo/GO_0006071 CHEBI:61873 biolink:ChemicalSubstance 2-demethylmenaquinol-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_61873 chebi_ph7_3 CHEBI:85846 biolink:ChemicalSubstance CDP-1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85846 CHEBI:85848 biolink:ChemicalSubstance CDP-1,2-dilinoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85848 GO:0031025 biolink:BiologicalProcess equatorial microtubule organizing center disassembly The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis. go-plus.json equatorial microtubule organising center disassembly http://purl.obolibrary.org/obo/GO_0031025 GO:0031026 biolink:CellularComponent glutamate synthase complex A complex that possesses glutamate synthase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0031026 goslim_pir GO:0031023 biolink:BiologicalProcess microtubule organizing center organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow. go-plus.json microtubule organising center organisation|microtubule organizing center organization and biogenesis http://purl.obolibrary.org/obo/GO_0031023 goslim_pir GO:0031024 biolink:BiologicalProcess interphase microtubule organizing center assembly The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center. go-plus.json interphase microtubule organizing centre assembly|interphase microtubule organizing center biogenesis|interphase microtubule organising center formation|interphase microtubule organising center biosynthesis http://purl.obolibrary.org/obo/GO_0031024 GO:0031021 biolink:CellularComponent interphase microtubule organizing center A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus. go-plus.json iMTOC|interphase microtubule organising center|interphase MTOC http://purl.obolibrary.org/obo/GO_0031021 GO:0031022 biolink:BiologicalProcess nuclear migration along microfilament The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. go-plus.json nuclear migration, microfilament-mediated http://purl.obolibrary.org/obo/GO_0031022 GO:0031020 biolink:CellularComponent plastid mRNA editing complex An mRNA editing complex found in a plastid. go-plus.json plastid editosome http://purl.obolibrary.org/obo/GO_0031020 GO:0021691 biolink:BiologicalProcess cerebellar Purkinje cell layer maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021691 GO:0021692 biolink:BiologicalProcess cerebellar Purkinje cell layer morphogenesis The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021692 GO:0021693 biolink:BiologicalProcess cerebellar Purkinje cell layer structural organization The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. go-plus.json cerebellar Purkinje cell layer structural organisation http://purl.obolibrary.org/obo/GO_0021693 CHEBI:71203 biolink:ChemicalSubstance beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_71203 chebi_ph7_3 GO:0021694 biolink:BiologicalProcess cerebellar Purkinje cell layer formation The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021694 GO:0031018 biolink:BiologicalProcess endocrine pancreas development The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. go-plus.json http://purl.obolibrary.org/obo/GO_0031018 GO:0021695 biolink:BiologicalProcess cerebellar cortex development The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. go-plus.json http://purl.obolibrary.org/obo/GO_0021695 GO:0031019 biolink:CellularComponent mitochondrial mRNA editing complex An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates. go-plus.json mitochondrial editosome http://purl.obolibrary.org/obo/GO_0031019 GO:0021696 biolink:BiologicalProcess cerebellar cortex morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. go-plus.json http://purl.obolibrary.org/obo/GO_0021696 GO:0021697 biolink:BiologicalProcess cerebellar cortex formation The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. go-plus.json http://purl.obolibrary.org/obo/GO_0021697 GO:0031016 biolink:BiologicalProcess pancreas development The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes. Wikipedia:Pancreas go-plus.json http://purl.obolibrary.org/obo/GO_0031016 CHEBI:71207 biolink:ChemicalSubstance (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71207 GO:0021698 biolink:BiologicalProcess cerebellar cortex structural organization The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. go-plus.json cerebellar cortex structural organisation http://purl.obolibrary.org/obo/GO_0021698 GO:0031017 biolink:BiologicalProcess exocrine pancreas development The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. go-plus.json http://purl.obolibrary.org/obo/GO_0031017 GO:0045600 biolink:BiologicalProcess positive regulation of fat cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. go-plus.json up regulation of fat cell differentiation|upregulation of fat cell differentiation|positive regulation of adipocyte differentiation|stimulation of fat cell differentiation|positive regulation of adipocyte cell differentiation|up-regulation of fat cell differentiation|activation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045600 GO:0045601 biolink:BiologicalProcess regulation of endothelial cell differentiation Any process that modulates the frequency, rate or extent of endothelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045601 CHEBI:71209 biolink:ChemicalSubstance N-(cyanomethyl)glycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_71209 GO:0006078 biolink:BiologicalProcess (1->6)-beta-D-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. go-plus.json beta-1,6 glucan biosynthetic process|beta-1,6 glucan biosynthesis|1,6-beta-glucan anabolism|1,6-beta-glucan biosynthetic process|1,6-beta-glucan biosynthesis|1,6-beta-glucan synthesis|1,6-beta-glucan formation|beta-1,6 glucan anabolism|beta-1,6 glucan synthesis|beta-1,6 glucan formation http://purl.obolibrary.org/obo/GO_0006078 GO:0006079 biolink:BiologicalProcess (1->6)-beta-D-glucan catabolic process The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans. go-plus.json 1,6-beta-D-glucan catabolic process|beta-1,6 glucan catabolism|beta-1,6 glucan degradation|beta-1,6 glucan breakdown|beta-1,6 glucan catabolic process|1,6-beta-D-glucan catabolism|1,6-beta-D-glucan degradation|1,6-beta-D-glucan breakdown http://purl.obolibrary.org/obo/GO_0006079 GO:0006076 biolink:BiologicalProcess (1->3)-beta-D-glucan catabolic process The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans. go-plus.json 1,3-beta-D-glucan catabolic process|1,3-beta-glucan degradation|beta-1,3 glucan degradation|beta-1,3 glucan catabolism|1,3-beta-glucan breakdown|1,3-beta-glucan catabolism|beta-1,3 glucan breakdown|beta-1,3 glucan catabolic process http://purl.obolibrary.org/obo/GO_0006076 GO:0006077 biolink:BiologicalProcess (1->6)-beta-D-glucan metabolic process The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds. go-plus.json 1,6-beta-glucan metabolic process|beta-1,6 glucan metabolism|beta-1,6 glucan metabolic process|1,6-beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0006077 GO:0006074 biolink:BiologicalProcess (1->3)-beta-D-glucan metabolic process The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds. go-plus.json 1,3-beta-D-glucan metabolic process|beta-1,3 glucan metabolic process|1,3-beta-glucan metabolic process|beta-1,3 glucan metabolism|1,3-beta-D-glucan metabolism http://purl.obolibrary.org/obo/GO_0006074 GO:0006075 biolink:BiologicalProcess (1->3)-beta-D-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds. go-plus.json beta-1,3 glucan biosynthetic process|beta-1,3 glucan biosynthesis|1,3-beta-glucan biosynthesis|1,3-beta-glucan anabolism|beta-1,3 glucan anabolism|1,3-beta-glucan synthesis|1,3-beta-D-glucan biosynthetic process|beta-1,3 glucan synthesis|1,3-beta-glucan formation|beta-1,3 glucan formation http://purl.obolibrary.org/obo/GO_0006075 GO:0021690 biolink:BiologicalProcess cerebellar molecular layer maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021690 CHEBI:85830 biolink:ChemicalSubstance CDP-1-palmitoyl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85830 GO:0045608 biolink:BiologicalProcess negative regulation of inner ear auditory receptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation. go-plus.json down-regulation of auditory receptor cell differentiation|negative regulation of auditory receptor cell differentiation|negative regulation of auditory hair cell differentiation|downregulation of auditory receptor cell differentiation|down regulation of auditory receptor cell differentiation|inhibition of auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_0045608 GO:0006083 biolink:BiologicalProcess acetate metabolic process The chemical reactions and pathways involving acetate, the anion of acetic acid. go-plus.json acetate metabolism http://purl.obolibrary.org/obo/GO_0006083 GO:0045609 biolink:BiologicalProcess positive regulation of inner ear auditory receptor cell differentiation Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation. go-plus.json up-regulation of auditory receptor cell differentiation|activation of auditory receptor cell differentiation|up regulation of auditory receptor cell differentiation|positive regulation of auditory receptor cell differentiation|positive regulation of auditory hair cell differentiation|upregulation of auditory receptor cell differentiation|stimulation of auditory receptor cell differentiation http://purl.obolibrary.org/obo/GO_0045609 GO:0006084 biolink:BiologicalProcess acetyl-CoA metabolic process The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. go-plus.json acetyl-CoA metabolism|acetyl coenzyme A metabolic process|acetyl coenzyme A metabolism http://purl.obolibrary.org/obo/GO_0006084 GO:0045606 biolink:BiologicalProcess positive regulation of epidermal cell differentiation Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. go-plus.json positive regulation of hypodermal cell differentiation|stimulation of epidermal cell differentiation|up-regulation of epidermal cell differentiation|activation of epidermal cell differentiation|up regulation of epidermal cell differentiation|upregulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045606 GO:0006081 biolink:BiologicalProcess cellular aldehyde metabolic process The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. go-plus.json alkanal metabolic process|alkanal metabolism|aldehyde metabolism http://purl.obolibrary.org/obo/GO_0006081 goslim_pir GO:0006082 biolink:BiologicalProcess organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. go-plus.json organic acid metabolism http://purl.obolibrary.org/obo/GO_0006082 goslim_pir GO:0045607 biolink:BiologicalProcess regulation of inner ear auditory receptor cell differentiation Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. go-plus.json regulation of auditory receptor cell differentiation|regulation of auditory hair cell differentiation http://purl.obolibrary.org/obo/GO_0045607 GO:0045604 biolink:BiologicalProcess regulation of epidermal cell differentiation Any process that modulates the frequency, rate or extent of epidermal cell differentiation. go-plus.json regulation of hypodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045604 GO:0006080 biolink:BiologicalProcess substituted mannan metabolic process The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units. go-plus.json substituted mannan metabolism http://purl.obolibrary.org/obo/GO_0006080 GO:0045605 biolink:BiologicalProcess negative regulation of epidermal cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. go-plus.json negative regulation of hypodermal cell differentiation|down-regulation of epidermal cell differentiation|downregulation of epidermal cell differentiation|down regulation of epidermal cell differentiation|inhibition of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045605 CHEBI:85835 biolink:ChemicalSubstance CDP-1,2-diarachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85835 CHEBI:61887 biolink:ChemicalSubstance N-acetylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_61887 chebi_ph7_3 GO:0045602 biolink:BiologicalProcess negative regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. go-plus.json down-regulation of endothelial cell differentiation|downregulation of endothelial cell differentiation|down regulation of endothelial cell differentiation|inhibition of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045602 GO:0045603 biolink:BiologicalProcess positive regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. go-plus.json up-regulation of endothelial cell differentiation|activation of endothelial cell differentiation|up regulation of endothelial cell differentiation|upregulation of endothelial cell differentiation|stimulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045603 GO:0031014 biolink:MolecularActivity troponin T binding Binding to troponin T, the tropomyosin-binding subunit of the troponin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031014 GO:0021699 biolink:BiologicalProcess cerebellar cortex maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. go-plus.json http://purl.obolibrary.org/obo/GO_0021699 CHEBI:85838 biolink:ChemicalSubstance CDP-1-stearoyl-2-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85838 GO:0031015 biolink:CellularComponent obsolete karyopherin docking complex OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p. go-plus.json karyopherin docking complex|Asm4p-containing complex|nuclear pore subcomplex http://purl.obolibrary.org/obo/GO_0031015 GO:0031012 biolink:CellularComponent extracellular matrix A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. NIF_Subcellular:nlx_subcell_20090513|Wikipedia:Extracellular_matrix go-plus.json proteinaceous extracellular matrix|matrisome http://purl.obolibrary.org/obo/GO_0031012 goslim_generic|goslim_chembl|goslim_pir|goslim_drosophila GO:0031013 biolink:MolecularActivity troponin I binding Binding to troponin I, the inhibitory subunit of the troponin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0031013 GO:0031010 biolink:CellularComponent ISWI-type complex Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair. go-plus.json http://purl.obolibrary.org/obo/GO_0031010 GO:0031011 biolink:CellularComponent Ino80 complex A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity. go-plus.json INO80 chromatin remodeling complex http://purl.obolibrary.org/obo/GO_0031011 GO:0021680 biolink:BiologicalProcess cerebellar Purkinje cell layer development The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021680 CHEBI:71211 biolink:ChemicalSubstance (4-coumaroyl)acetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71211 chebi_ph7_3 CHEBI:71212 biolink:ChemicalSubstance prohormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_71212 GO:0021681 biolink:BiologicalProcess cerebellar granular layer development The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0021681 CHEBI:71213 biolink:ChemicalSubstance 3-oxocyclopentanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71213 GO:0021682 biolink:BiologicalProcess nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0021682 GO:0031009 biolink:CellularComponent plastid ADPG pyrophosphorylase complex An ADPG pyrophosphorylase complex found in a plastid. go-plus.json http://purl.obolibrary.org/obo/GO_0031009 GO:0021683 biolink:BiologicalProcess cerebellar granular layer morphogenesis The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0021683 CHEBI:71214 biolink:ChemicalSubstance 4-methoxy-4-oxo-3-phenylbutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_71214 GO:0021684 biolink:BiologicalProcess cerebellar granular layer formation The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0021684 GO:0031007 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031007 CHEBI:71215 biolink:ChemicalSubstance (4-coumaroyl)acetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_71215 GO:0021685 biolink:BiologicalProcess cerebellar granular layer structural organization The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. go-plus.json cerebellar granular layer structural organisation http://purl.obolibrary.org/obo/GO_0021685 GO:0031008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031008 GO:0021686 biolink:BiologicalProcess cerebellar granular layer maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0021686 GO:0031005 biolink:MolecularActivity filamin binding Binding to a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain. go-plus.json filamin-3 binding|filamin-2 binding|filamin-1 binding|beta-filamin binding|ABPL binding|filamin B binding|filamin A binding|ABP-278/276 binding|filamin C binding|gamma-filamin binding|filamin-C binding|filamin-A binding|ABP-280 binding|alpha-filamin binding|filamin-B binding http://purl.obolibrary.org/obo/GO_0031005 GO:0006049 biolink:BiologicalProcess UDP-N-acetylglucosamine catabolic process The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. go-plus.json UDP-N-acetylglucosamine catabolism|UDP-N-acetylglucosamine degradation|UDP-N-acetylglucosamine breakdown http://purl.obolibrary.org/obo/GO_0006049 GO:0031006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0031006 GO:0021687 biolink:BiologicalProcess cerebellar molecular layer morphogenesis The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021687 GO:0045611 biolink:BiologicalProcess negative regulation of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation. go-plus.json down-regulation of hemocyte differentiation|negative regulation of arthropod blood cell differentiation|downregulation of hemocyte differentiation|down regulation of hemocyte differentiation|inhibition of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045611 GO:0006047 biolink:BiologicalProcess UDP-N-acetylglucosamine metabolic process The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. go-plus.json UDP-N-acetylglucosamine metabolism http://purl.obolibrary.org/obo/GO_0006047 GO:0006048 biolink:BiologicalProcess UDP-N-acetylglucosamine biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. MetaCyc:UDPNAGSYN-PWY go-plus.json UDP-N-acetylglucosamine anabolism|UDP-N-acetylglucosamine synthesis|UDP-N-acetylglucosamine formation|UDP-N-acetylglucosamine biosynthesis|UDP-GlcNAc biosynthesis|UDP-GlcNAc biosynthetic process http://purl.obolibrary.org/obo/GO_0006048 GO:0045612 biolink:BiologicalProcess positive regulation of hemocyte differentiation Any process that activates or increases the frequency, rate or extent of hemocyte differentiation. go-plus.json stimulation of hemocyte differentiation|activation of hemocyte differentiation|up-regulation of hemocyte differentiation|positive regulation of arthropod blood cell differentiation|up regulation of hemocyte differentiation|upregulation of hemocyte differentiation http://purl.obolibrary.org/obo/GO_0045612 GO:0006045 biolink:BiologicalProcess N-acetylglucosamine biosynthetic process The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. go-plus.json N-acetylglucosamine anabolism|N-acetylglucosamine biosynthesis|N-acetylglucosamine synthesis|N-acetylglucosamine formation http://purl.obolibrary.org/obo/GO_0006045 GO:0045610 biolink:BiologicalProcess regulation of hemocyte differentiation Any process that modulates the frequency, rate or extent of hemocyte differentiation. go-plus.json regulation of arthropod blood cell differentiation http://purl.obolibrary.org/obo/GO_0045610 GO:0006046 biolink:BiologicalProcess N-acetylglucosamine catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. go-plus.json N-acetylglucosamine degradation|N-acetylglucosamine breakdown|N-acetylglucosamine catabolism http://purl.obolibrary.org/obo/GO_0006046 GO:0006043 biolink:BiologicalProcess glucosamine catabolic process The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. MetaCyc:GLUAMCAT-PWY go-plus.json glucosamine degradation|glucosamine breakdown|chitosamine catabolic process|glucosamine catabolism|chitosamine catabolism http://purl.obolibrary.org/obo/GO_0006043 GO:0006044 biolink:BiologicalProcess N-acetylglucosamine metabolic process The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. go-plus.json N-acetylglucosamine metabolism http://purl.obolibrary.org/obo/GO_0006044 GO:0006041 biolink:BiologicalProcess glucosamine metabolic process The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. go-plus.json chitosamine metabolic process|glucosamine metabolism|chitosamine metabolism http://purl.obolibrary.org/obo/GO_0006041 CHEBI:61891 biolink:ChemicalSubstance N(5)-methyl-L-glutamine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61891 chebi_ph7_3 GO:0006042 biolink:BiologicalProcess glucosamine biosynthetic process The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. go-plus.json glucosamine anabolism|glucosamine synthesis|glucosamine biosynthesis|glucosamine formation|chitosamine biosynthesis|chitosamine biosynthetic process http://purl.obolibrary.org/obo/GO_0006042 GO:0045619 biolink:BiologicalProcess regulation of lymphocyte differentiation Any process that modulates the frequency, rate or extent of lymphocyte differentiation. go-plus.json regulation of lymphocyte development http://purl.obolibrary.org/obo/GO_0045619 GO:0006050 biolink:BiologicalProcess mannosamine metabolic process The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins. go-plus.json mannosamine metabolism http://purl.obolibrary.org/obo/GO_0006050 CHEBI:61896 biolink:ChemicalSubstance N(omega),N(omega)-dimethyl-L-arginine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61896 GO:0006051 biolink:BiologicalProcess N-acetylmannosamine metabolic process The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. go-plus.json N-acetylmannosamine metabolism http://purl.obolibrary.org/obo/GO_0006051 CHEBI:61897 biolink:ChemicalSubstance N(omega),N(omega)-dimethyl-L-arginine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_61897 chebi_ph7_3 GO:0045617 biolink:BiologicalProcess negative regulation of keratinocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. go-plus.json down-regulation of keratinocyte differentiation|downregulation of keratinocyte differentiation|down regulation of keratinocyte differentiation|inhibition of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045617 GO:0045618 biolink:BiologicalProcess positive regulation of keratinocyte differentiation Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. go-plus.json stimulation of keratinocyte differentiation|up-regulation of keratinocyte differentiation|activation of keratinocyte differentiation|up regulation of keratinocyte differentiation|upregulation of keratinocyte differentiation http://purl.obolibrary.org/obo/GO_0045618 GO:0045615 biolink:BiologicalProcess positive regulation of plasmatocyte differentiation Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation. go-plus.json upregulation of plasmatocyte differentiation|stimulation of plasmatocyte differentiation|up-regulation of plasmatocyte differentiation|activation of plasmatocyte differentiation|up regulation of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045615 GO:0045616 biolink:BiologicalProcess regulation of keratinocyte differentiation Any process that modulates the frequency, rate or extent of keratinocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045616 GO:0045613 biolink:BiologicalProcess regulation of plasmatocyte differentiation Any process that modulates the frequency, rate or extent of plasmatocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0045613 CHEBI:61898 biolink:ChemicalSubstance alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_61898 GO:0045614 biolink:BiologicalProcess negative regulation of plasmatocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation. go-plus.json down-regulation of plasmatocyte differentiation|downregulation of plasmatocyte differentiation|down regulation of plasmatocyte differentiation|inhibition of plasmatocyte differentiation http://purl.obolibrary.org/obo/GO_0045614 GO:0021688 biolink:BiologicalProcess cerebellar molecular layer formation The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021688 GO:0031003 biolink:CellularComponent actin tubule A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together. go-plus.json http://purl.obolibrary.org/obo/GO_0031003 GO:0021689 biolink:BiologicalProcess cerebellar molecular layer structural organization The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. go-plus.json cerebellar molecular layer structural organisation http://purl.obolibrary.org/obo/GO_0021689 GO:0031004 biolink:CellularComponent potassium ion-transporting ATPase complex Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex. go-plus.json Kdp system complex http://purl.obolibrary.org/obo/GO_0031004 GO:0031001 biolink:BiologicalProcess response to brefeldin A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0031001 GO:0031002 biolink:CellularComponent actin rod A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0031002 GO:0031000 biolink:BiologicalProcess response to caffeine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them. go-plus.json http://purl.obolibrary.org/obo/GO_0031000 GO:0021670 biolink:BiologicalProcess lateral ventricle development The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0021670 GO:0021671 biolink:BiologicalProcess rhombomere 7 morphogenesis The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021671 CHEBI:71224 biolink:ChemicalSubstance flavan-3,3',4',5,5',7-hexol go-plus.json http://purl.obolibrary.org/obo/CHEBI_71224 chebi_ph7_3 GO:0021672 biolink:BiologicalProcess rhombomere 7 structural organization The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 7 structural organisation http://purl.obolibrary.org/obo/GO_0021672 GO:0021673 biolink:BiologicalProcess rhombomere 7 formation The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021673 GO:0021674 biolink:BiologicalProcess rhombomere 8 morphogenesis The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021674 CHEBI:71227 biolink:ChemicalSubstance (+)-epigallocatechin go-plus.json http://purl.obolibrary.org/obo/CHEBI_71227 chebi_ph7_3 GO:0021675 biolink:BiologicalProcess nerve development The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0021675 GO:0021676 biolink:BiologicalProcess rhombomere 8 structural organization The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. go-plus.json rhombomere 8 structural organisation http://purl.obolibrary.org/obo/GO_0021676 GO:0006058 biolink:BiologicalProcess mannoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues. go-plus.json mannoprotein degradation|mannoprotein breakdown|mannoprotein catabolism http://purl.obolibrary.org/obo/GO_0006058 GO:0045622 biolink:BiologicalProcess regulation of T-helper cell differentiation Any process that modulates the frequency, rate or extent of T-helper cell differentiation. go-plus.json regulation of T-helper cell development http://purl.obolibrary.org/obo/GO_0045622 CHEBI:46280 biolink:ChemicalSubstance beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_46280 GO:0045623 biolink:BiologicalProcess negative regulation of T-helper cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation. go-plus.json negative regulation of T-helper cell development|down-regulation of T-helper cell differentiation|inhibition of T-helper cell differentiation|down regulation of T-helper cell differentiation|downregulation of T-helper cell differentiation http://purl.obolibrary.org/obo/GO_0045623 GO:0006059 biolink:BiologicalProcess hexitol metabolic process The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule. go-plus.json sugar alcohol (hexitol) metabolic process|hexitol metabolism|sugar alcohol (hexitol) metabolism http://purl.obolibrary.org/obo/GO_0006059 GO:0045620 biolink:BiologicalProcess negative regulation of lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. go-plus.json negative regulation of lymphocyte development|down-regulation of lymphocyte differentiation|downregulation of lymphocyte differentiation|down regulation of lymphocyte differentiation|inhibition of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045620 GO:0006056 biolink:BiologicalProcess mannoprotein metabolic process The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues. go-plus.json mannoprotein metabolism http://purl.obolibrary.org/obo/GO_0006056 GO:0006057 biolink:BiologicalProcess mannoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues. go-plus.json mannoprotein biosynthesis|mannoprotein anabolism|mannoprotein synthesis|mannoprotein formation http://purl.obolibrary.org/obo/GO_0006057 GO:0045621 biolink:BiologicalProcess positive regulation of lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. go-plus.json positive regulation of lymphocyte development|up regulation of lymphocyte differentiation|upregulation of lymphocyte differentiation|stimulation of lymphocyte differentiation|up-regulation of lymphocyte differentiation|activation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0045621 GO:0006054 biolink:BiologicalProcess N-acetylneuraminate metabolic process The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. go-plus.json N-acetylneuraminate metabolism|sialic acid metabolism|sialic acid metabolic process http://purl.obolibrary.org/obo/GO_0006054 GO:0006055 biolink:BiologicalProcess CMP-N-acetylneuraminate biosynthetic process The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate. go-plus.json CMP-N-acetylneuraminate formation|CMP-N-acetylneuraminate biosynthesis|CMP-N-acetylneuraminate anabolism|CMP-N-acetylneuraminate synthesis http://purl.obolibrary.org/obo/GO_0006055 GO:0006052 biolink:BiologicalProcess N-acetylmannosamine biosynthetic process The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. go-plus.json N-acetylmannosamine anabolism|N-acetylmannosamine synthesis|N-acetylmannosamine formation|N-acetylmannosamine biosynthesis http://purl.obolibrary.org/obo/GO_0006052 GO:0006053 biolink:BiologicalProcess N-acetylmannosamine catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. go-plus.json N-acetylmannosamine degradation|N-acetylmannosamine breakdown|N-acetylmannosamine catabolism http://purl.obolibrary.org/obo/GO_0006053 GO:0006061 biolink:BiologicalProcess sorbitol biosynthetic process The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. go-plus.json sorbitol biosynthesis|sorbitol anabolism|sorbitol synthesis|sorbitol formation http://purl.obolibrary.org/obo/GO_0006061 GO:0006062 biolink:BiologicalProcess sorbitol catabolic process The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. MetaCyc:SORBDEG-PWY go-plus.json sorbitol catabolism|sorbitol degradation|sorbitol breakdown http://purl.obolibrary.org/obo/GO_0006062 GO:0045628 biolink:BiologicalProcess regulation of T-helper 2 cell differentiation Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation. go-plus.json regulation of T-helper 2 cell development http://purl.obolibrary.org/obo/GO_0045628 GO:0045629 biolink:BiologicalProcess negative regulation of T-helper 2 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation. go-plus.json down regulation of T-helper 2 cell differentiation|downregulation of T-helper 2 cell differentiation|negative regulation of T-helper 2 cell development|down-regulation of T-helper 2 cell differentiation|inhibition of T-helper 2 cell differentiation http://purl.obolibrary.org/obo/GO_0045629 GO:0006060 biolink:BiologicalProcess sorbitol metabolic process The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. MetaCyc:P461-PWY go-plus.json sorbitol metabolism http://purl.obolibrary.org/obo/GO_0006060 GO:0045626 biolink:BiologicalProcess negative regulation of T-helper 1 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation. go-plus.json down regulation of T-helper 1 cell differentiation|downregulation of T-helper 1 cell differentiation|negative regulation of T-helper 1 cell development|down-regulation of T-helper 1 cell differentiation|inhibition of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045626 CHEBI:85856 biolink:ChemicalSubstance CDP-1,2-dioleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_85856 GO:0045627 biolink:BiologicalProcess positive regulation of T-helper 1 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation. go-plus.json upregulation of T-helper 1 cell differentiation|up regulation of T-helper 1 cell differentiation|positive regulation of T-helper 1 cell development|activation of T-helper 1 cell differentiation|stimulation of T-helper 1 cell differentiation|up-regulation of T-helper 1 cell differentiation http://purl.obolibrary.org/obo/GO_0045627 GO:0045624 biolink:BiologicalProcess positive regulation of T-helper cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation. go-plus.json stimulation of T-helper cell differentiation|up-regulation of T-helper cell differentiation|upregulation of T-helper cell differentiation|up regulation of T-helper cell differentiation|activation of T-helper cell differentiation|positive regulation of T-helper cell development http://purl.obolibrary.org/obo/GO_0045624 GO:0045625 biolink:BiologicalProcess regulation of T-helper 1 cell differentiation Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. go-plus.json regulation of T-helper 1 cell development http://purl.obolibrary.org/obo/GO_0045625 GO:0021677 biolink:BiologicalProcess rhombomere 8 formation The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. go-plus.json http://purl.obolibrary.org/obo/GO_0021677 GO:0021678 biolink:BiologicalProcess third ventricle development The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. go-plus.json http://purl.obolibrary.org/obo/GO_0021678 GO:0021679 biolink:BiologicalProcess cerebellar molecular layer development The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. go-plus.json http://purl.obolibrary.org/obo/GO_0021679 CHEBI:71221 biolink:ChemicalSubstance feruloylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71221 chebi_ph7_3 CHEBI:224366 biolink:ChemicalSubstance tert-butylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_224366 chebi_ph7_3 CHEBI:12834 biolink:ChemicalSubstance n-alkanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_12834 chebi_ph7_3 NCBITaxon:33634 biolink:OrganismalEntity Stramenopiles go-plus.json Heterokonta|Chromophyta|heterokonts|Straminipila http://purl.obolibrary.org/obo/NCBITaxon_33634 NCBITaxon:33630 biolink:OrganismalEntity Alveolata go-plus.json alveolates http://purl.obolibrary.org/obo/NCBITaxon_33630 NCBITaxon:33682 biolink:OrganismalEntity Euglenozoa go-plus.json Euglenozoans http://purl.obolibrary.org/obo/NCBITaxon_33682 CHEBI:61817 biolink:ChemicalSubstance 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61817 CHEBI:61820 biolink:ChemicalSubstance beta-D-Gal-(1->3)-alpha-D-GalNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_61820 chebi_ph7_3 CHEBI:61822 biolink:ChemicalSubstance 2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_61822 GO:0045592 biolink:BiologicalProcess regulation of cumulus cell differentiation Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation. go-plus.json regulation of ovarian cumulus cell differentiation http://purl.obolibrary.org/obo/GO_0045592 GO:0045593 biolink:BiologicalProcess negative regulation of cumulus cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation. go-plus.json downregulation of cumulus cell differentiation|down regulation of cumulus cell differentiation|inhibition of cumulus cell differentiation|negative regulation of ovarian cumulus cell differentiation|down-regulation of cumulus cell differentiation http://purl.obolibrary.org/obo/GO_0045593 GO:0045590 biolink:BiologicalProcess negative regulation of regulatory T cell differentiation Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells. go-plus.json down regulation of regulatory T cell differentiation|negative regulation of regulatory T-cell differentiation|negative regulation of suppressor T-cell differentiation|downregulation of regulatory T cell differentiation|negative regulation of regulatory T-lymphocyte differentiation|negative regulation of regulatory T cell development|negative regulation of suppressor T cell differentiation|down-regulation of regulatory T cell differentiation|negative regulation of regulatory T lymphocyte differentiation|inhibition of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045590 GO:0045591 biolink:BiologicalProcess positive regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells. go-plus.json positive regulation of suppressor T-cell differentiation|positive regulation of regulatory T-cell differentiation|upregulation of regulatory T cell differentiation|positive regulation of regulatory T-lymphocyte differentiation|up regulation of regulatory T cell differentiation|positive regulation of regulatory T cell development|activation of regulatory T cell differentiation|positive regulation of suppressor T cell differentiation|stimulation of regulatory T cell differentiation|positive regulation of regulatory T lymphocyte differentiation|up-regulation of regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0045591 CHEBI:22221 biolink:ChemicalSubstance acyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_22221 GO:0045598 biolink:BiologicalProcess regulation of fat cell differentiation Any process that modulates the frequency, rate or extent of adipocyte differentiation. go-plus.json regulation of adipocyte cell differentiation|regulation of adipocyte differentiation http://purl.obolibrary.org/obo/GO_0045598 GO:0045599 biolink:BiologicalProcess negative regulation of fat cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. go-plus.json negative regulation of adipocyte differentiation|down-regulation of fat cell differentiation|downregulation of fat cell differentiation|down regulation of fat cell differentiation|inhibition of fat cell differentiation|negative regulation of adipocyte cell differentiation http://purl.obolibrary.org/obo/GO_0045599 GO:0045596 biolink:BiologicalProcess negative regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. go-plus.json down-regulation of cell differentiation|downregulation of cell differentiation|down regulation of cell differentiation|inhibition of cell differentiation http://purl.obolibrary.org/obo/GO_0045596 GO:0045597 biolink:BiologicalProcess positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of cell differentiation. go-plus.json stimulation of cell differentiation|up-regulation of cell differentiation|activation of cell differentiation|up regulation of cell differentiation|upregulation of cell differentiation http://purl.obolibrary.org/obo/GO_0045597 GO:0045594 biolink:BiologicalProcess positive regulation of cumulus cell differentiation Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation. go-plus.json up regulation of cumulus cell differentiation|upregulation of cumulus cell differentiation|stimulation of cumulus cell differentiation|up-regulation of cumulus cell differentiation|activation of cumulus cell differentiation|positive regulation of ovarian cumulus cell differentiation http://purl.obolibrary.org/obo/GO_0045594 GO:0045595 biolink:BiologicalProcess regulation of cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. go-plus.json http://purl.obolibrary.org/obo/GO_0045595 CHEBI:36863 biolink:ChemicalSubstance 22-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36863 CHEBI:36864 biolink:ChemicalSubstance 25-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36864 CHEBI:36861 biolink:ChemicalSubstance 14alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36861 CHEBI:71190 biolink:ChemicalSubstance 4-methoxy-4-oxo-3-phenylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71190 chebi_ph7_3 GO:0070558 biolink:CellularComponent alphaM-beta2 integrin-CD63 complex A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family. go-plus.json ITGAM-ITGB2-CD63 complex http://purl.obolibrary.org/obo/GO_0070558 CHEBI:36865 biolink:ChemicalSubstance 24-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36865 CHEBI:36866 biolink:ChemicalSubstance 23-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36866 GO:0070559 biolink:CellularComponent lysosomal multienzyme complex A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism. go-plus.json GALNS-lysosomal hydrolase 1.27 MDa complex http://purl.obolibrary.org/obo/GO_0070559 CHEBI:71191 biolink:ChemicalSubstance 3-oxocyclopentanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71191 chebi_ph7_3 UBERON:0003458 biolink:AnatomicalEntity neck bone A bone that is part of a neck [Automatically generated definition]. go-plus.json neck (volume) bone organ|bone of neck|bone organ of neck (volume)|bone organ of neck|neck (volume) bone|bone of neck (volume)|neck bone organ http://purl.obolibrary.org/obo/UBERON_0003458 CHEBI:71192 biolink:ChemicalSubstance N-(cyanomethyl)glycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71192 chebi_ph7_3 GO:0070556 biolink:CellularComponent TAF4B-containing transcription factor TFIID complex A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4. go-plus.json TFIID complex, B-cell specific http://purl.obolibrary.org/obo/GO_0070556 UBERON:0003459 biolink:AnatomicalEntity chest bone A bone that is part of a chest [Automatically generated definition]. go-plus.json bone organ of anterolateral part of thorax|anterior thoracic region bone|anterolateral part of thorax bone organ|bone of anterior thoracic region|front of thorax bone|bone organ of chest|bone organ of front of thorax|anterior thoracic region bone organ|bone of anterolateral part of thorax|bone organ of anterior thoracic region|anterolateral part of thorax bone|front of thorax bone organ|chest bone organ|bone of chest|bone of front of thorax http://purl.obolibrary.org/obo/UBERON_0003459 GO:0070557 biolink:CellularComponent PCNA-p21 complex A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0070557 UBERON:0003456 biolink:AnatomicalEntity respiratory system lymphatic vessel A lymphatic vessel that is part of a respiratory system [Automatically generated definition]. go-plus.json lymph vessel of respiratory system|apparatus respiratorius lymph vessel|lymphatic vessel of apparatus respiratorius|lymphatic vessel of respiratory system|respiratory system lymph vessel|apparatus respiratorius lymphatic vessel|lymph vessel of apparatus respiratorius http://purl.obolibrary.org/obo/UBERON_0003456 GO:0070554 biolink:CellularComponent synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof). go-plus.json Stx3-Snap25-Vamp2-Cplx1 complex|SNARE complex (Stx3, Snap25, Vamp2, Cplx1) http://purl.obolibrary.org/obo/GO_0070554 UBERON:0003457 biolink:AnatomicalEntity head bone A bone that is part of a head [Automatically generated definition]. go-plus.json bone organ of adult head|bone organ of head|adult head bone|head bone organ|bone of adult head|craniofacial bone|adult head bone organ|bone of head http://purl.obolibrary.org/obo/UBERON_0003457 GO:0070555 biolink:BiologicalProcess response to interleukin-1 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. go-plus.json response to IL-1 http://purl.obolibrary.org/obo/GO_0070555 CHEBI:22229 biolink:ChemicalSubstance acylglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_22229 UBERON:0003454 biolink:AnatomicalEntity small intestine Peyer's patch nodular lymphoid structures on the serosal surface of the small intestine. go-plus.json noduli lymphoidei aggregati intestini tenuis|Peyer's patch of small bowel|Peyer's patch of small intestine|small bowel Peyer's patch|Peyer's patch|aggregated lymphoid follicle of small intestine|small intestine Peyer's patch http://purl.obolibrary.org/obo/UBERON_0003454 GO:0070552 biolink:CellularComponent BRISC complex A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains. go-plus.json http://purl.obolibrary.org/obo/GO_0070552 UBERON:0003455 biolink:AnatomicalEntity inner renal medulla loop of Henle A loop of Henle that is part of a inner medulla of kidney [Automatically generated definition]. go-plus.json loop of Henle, inner medullary portion|kidney inner medulla loop of Henle http://purl.obolibrary.org/obo/UBERON_0003455 GO:0070553 biolink:MolecularActivity nicotinic acid receptor activity Combining with nicotinic acid to initiate a change in cell activity. go-plus.json niacin receptor activity http://purl.obolibrary.org/obo/GO_0070553 CHEBI:36860 biolink:ChemicalSubstance 14-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36860 UBERON:0003452 biolink:AnatomicalEntity trabecula carnea cardiac muscle tissue A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]. go-plus.json trabecula carnea muscle of heart muscle tissue|textus muscularis of myocardium of trabecula carnea|cardiac muscle of trabecula carnea|trabecula carnea textus muscularis of cardiac muscle|cardiac muscle textus muscularis of trabecula carnea|trabecula carnea muscle tissue of muscle of heart|textus muscularis of heart muscle of trabecula carnea|muscle tissue of cardiac muscle of trabecula carnea|trabecula carnea myocardium textus muscularis|textus muscularis of heart myocardium of trabecula carnea|trabecula carnea heart muscle textus muscularis|trabecula carnea cardiac muscle muscle tissue|cardiac muscle tissue of trabecula carnea|muscle tissue of muscle of heart of trabecula carnea|myocardium textus muscularis of trabecula carnea|trabecula carnea textus muscularis of myocardium|trabecula carnea heart myocardium textus muscularis|muscle tissue of myocardium of trabecula carnea|muscle of heart textus muscularis of trabecula carnea|cardiac muscle muscle tissue of trabecula carnea|heart muscle textus muscularis of trabecula carnea|trabecula carnea muscle tissue of cardiac muscle|trabecula carnea textus muscularis of heart muscle|trabecula carnea textus muscularis of muscle of heart|muscle tissue of heart muscle of trabecula carnea|trabecula carnea textus muscularis of heart myocardium|heart myocardium textus muscularis of trabecula carnea|trabecula carnea myocardium muscle tissue|muscle tissue of heart myocardium of trabecula carnea|textus muscularis of muscle of heart of trabecula carnea|trabecula carnea heart muscle muscle tissue|myocardium muscle tissue of trabecula carnea|trabecula carnea muscle tissue of myocardium|trabecula carnea muscle of heart textus muscularis|trabecula carnea heart myocardium muscle tissue|muscle of heart muscle tissue of trabecula carnea|heart muscle muscle tissue of trabecula carnea|trabecula carnea muscle tissue of heart muscle|textus muscularis of cardiac muscle of trabecula carnea|heart myocardium muscle tissue of trabecula carnea|trabecula carnea muscle tissue of heart myocardium|trabecula carnea cardiac muscle|trabecula carnea cardiac muscle textus muscularis http://purl.obolibrary.org/obo/UBERON_0003452 CHEBI:71198 biolink:ChemicalSubstance (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_71198 chebi_ph7_3 GO:0070550 biolink:BiologicalProcess rDNA condensation The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase. go-plus.json rDNA packaging http://purl.obolibrary.org/obo/GO_0070550 GO:0070551 biolink:MolecularActivity endoribonuclease activity, cleaving siRNA-paired mRNA Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters. go-plus.json argonaute endoribonuclease activity http://purl.obolibrary.org/obo/GO_0070551 UBERON:0003453 biolink:AnatomicalEntity large intestine Peyer's patch A Peyer's patch that is part of a large intestine. go-plus.json solitary lymphoid follicle of subdivision of large intestine|large intestine Peyer's patch|Peyer's patch of large intestine|solitary lymphatic follicle of large intestine http://purl.obolibrary.org/obo/UBERON_0003453 CHEBI:71199 biolink:ChemicalSubstance hydroxymethylphosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_71199 chebi_ph7_3 CHEBI:22231 biolink:ChemicalSubstance acylglycerone phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_22231 NCBITaxon:1003877 biolink:OrganismalEntity Benincaseae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1003877 UBERON:0003438 biolink:AnatomicalEntity iris nerve Any nerve that innervates the iris. go-plus.json nerve of iris|ciliary nerve http://purl.obolibrary.org/obo/UBERON_0003438 CHEBI:22235 biolink:ChemicalSubstance adamantanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_22235 UBERON:0003439 biolink:AnatomicalEntity nerve of trunk region A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk). go-plus.json nerve of trunk|nerve of torso|torso nerve|trunk nerve http://purl.obolibrary.org/obo/UBERON_0003439 CHEBI:36874 biolink:ChemicalSubstance radical cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_36874 UBERON:0003440 biolink:AnatomicalEntity limb nerve A nerve that is part of a limb [Automatically generated definition]. go-plus.json nerve of limb http://purl.obolibrary.org/obo/UBERON_0003440 CHEBI:36875 biolink:ChemicalSubstance radical ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36875 CHEBI:12886 biolink:ChemicalSubstance (R)-4'-phosphopantothenate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_12886 CHEBI:36872 biolink:ChemicalSubstance organic radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_36872 NCBITaxon:9443 biolink:OrganismalEntity Primates go-plus.json primate|Primata|primates http://purl.obolibrary.org/obo/NCBITaxon_9443 CHEBI:36873 biolink:ChemicalSubstance radical anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36873 GO:0070549 biolink:BiologicalProcess negative regulation of translation involved in RNA interference A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA. go-plus.json down-regulation of translation involved in RNA interference|RNA interference, negative regulation of translation|downregulation of translation involved in RNA interference|down regulation of translation involved in RNA interference|inhibition of translation involved in RNA interference http://purl.obolibrary.org/obo/GO_0070549 CHEBI:36878 biolink:ChemicalSubstance inorganic radical ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36878 CHEBI:36879 biolink:ChemicalSubstance inorganic radical cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_36879 GO:0070547 biolink:MolecularActivity L-tyrosine aminotransferase activity Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070547 CHEBI:36876 biolink:ChemicalSubstance inorganic radical anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36876 GO:0070548 biolink:MolecularActivity L-glutamine aminotransferase activity Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070548 CHEBI:36877 biolink:ChemicalSubstance organic radical anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36877 UBERON:0003447 biolink:AnatomicalEntity digit nerve of manus A nerve that is part of a finger [Automatically generated definition]. go-plus.json nerve of finger|finger nerve|nerve of digit of hand|nerve of digitus manus|nerve of hand digit|digit of hand nerve|digitus manus nerve|nerve of digit of terminal segment of free upper limb|hand digit nerve|nerve of terminal segment of free upper limb digit|terminal segment of free upper limb digit nerve|digit of terminal segment of free upper limb nerve http://purl.obolibrary.org/obo/UBERON_0003447 GO:0070545 biolink:CellularComponent PeBoW complex A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0070545 UBERON:0003448 biolink:AnatomicalEntity manus nerve A nerve that is part of a manus [Automatically generated definition]. go-plus.json hand nerve|nerve of manus|nerve of hand http://purl.obolibrary.org/obo/UBERON_0003448 GO:0070546 biolink:MolecularActivity L-phenylalanine aminotransferase activity Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070546 GO:0070543 biolink:BiologicalProcess response to linoleic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus. go-plus.json response to linoleate http://purl.obolibrary.org/obo/GO_0070543 UBERON:0003445 biolink:AnatomicalEntity pes nerve A nerve that is part of a foot [Automatically generated definition]. go-plus.json foot nerve|nerve of foot http://purl.obolibrary.org/obo/UBERON_0003445 UBERON:0003446 biolink:AnatomicalEntity ankle nerve A nerve that is part of an ankle [Automatically generated definition]. go-plus.json neural network of ankle|tarsal region nerve|nerve of ankle http://purl.obolibrary.org/obo/UBERON_0003446 GO:0070544 biolink:BiologicalProcess histone H3-K36 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone. go-plus.json H3K36 demethylation http://purl.obolibrary.org/obo/GO_0070544 GO:0070541 biolink:BiologicalProcess response to platinum ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus. go-plus.json response to platinum http://purl.obolibrary.org/obo/GO_0070541 UBERON:0003443 biolink:AnatomicalEntity thoracic cavity nerve A nerve that is located in a thoracic cavity [Automatically generated definition]. go-plus.json cavity of thorax nerve|nerve of thoracic cavity|nerve of cavity of chest|nerve of pectoral cavity|cavity of chest nerve|pectoral cavity nerve|nerve of chest cavity|nerve of cavity of thorax|chest cavity nerve http://purl.obolibrary.org/obo/UBERON_0003443 GO:0070542 biolink:BiologicalProcess response to fatty acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0070542 UBERON:0003444 biolink:AnatomicalEntity pelvis nerve A nerve that is part of a pelvis [Automatically generated definition]. go-plus.json nerve of pelvis http://purl.obolibrary.org/obo/UBERON_0003444 CHEBI:36871 biolink:ChemicalSubstance inorganic radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_36871 UBERON:0003441 biolink:AnatomicalEntity forelimb nerve A nerve that is part of a forelimb [Automatically generated definition]. go-plus.json wing nerve|nerve of superior member|nerve of upper extremity|nerve of fore limb|nerve of forelimb|fore limb nerve http://purl.obolibrary.org/obo/UBERON_0003441 UBERON:0003442 biolink:AnatomicalEntity hindlimb nerve A nerve that is part of a hindlimb [Automatically generated definition]. go-plus.json nerve of hindlimb|nerve of inferior member|nerve of hind limb|hind limb nerve|nerve of lower extremity http://purl.obolibrary.org/obo/UBERON_0003442 GO:0070540 biolink:MolecularActivity stearic acid binding Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0070540 GO:0070570 biolink:BiologicalProcess regulation of neuron projection regeneration Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. go-plus.json http://purl.obolibrary.org/obo/GO_0070570 CHEBI:22200 biolink:ChemicalSubstance acetylgentamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22200 CHEBI:22201 biolink:ChemicalSubstance acetylkanamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_22201 GO:0070571 biolink:BiologicalProcess negative regulation of neuron projection regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. go-plus.json growth cone collapse http://purl.obolibrary.org/obo/GO_0070571 UBERON:0003429 biolink:AnatomicalEntity abdomen nerve A nerve that is part of an abdomen [Automatically generated definition]. go-plus.json nerve of abdomen http://purl.obolibrary.org/obo/UBERON_0003429 CHEBI:22204 biolink:ChemicalSubstance acetylspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22204 CHEBI:22205 biolink:ChemicalSubstance acetylspermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_22205 UBERON:0003427 biolink:AnatomicalEntity abdominal fat pad The encapsulated adipose tissue in the abdomen. go-plus.json abdominal fat depot|abdomen fat pad|fat pad of abdomen http://purl.obolibrary.org/obo/UBERON_0003427 UBERON:0003428 biolink:AnatomicalEntity gonadal fat pad The encapsulated adipose tissue associated with the ovaries or testes. go-plus.json gonadal fat depot|gonadal fat pad|fat pad of gonads|gonad-associated fat pad|gonad fat pad|fat pad of gonad http://purl.obolibrary.org/obo/UBERON_0003428 CHEBI:36849 biolink:ChemicalSubstance 6-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36849 CHEBI:36847 biolink:ChemicalSubstance 12beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36847 CHEBI:36848 biolink:ChemicalSubstance 5-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36848 CHEBI:36841 biolink:ChemicalSubstance 11-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36841 CHEBI:36842 biolink:ChemicalSubstance 19-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36842 CHEBI:36840 biolink:ChemicalSubstance 16-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36840 CHEBI:36845 biolink:ChemicalSubstance 12-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36845 CHEBI:36846 biolink:ChemicalSubstance 12alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36846 CHEBI:36843 biolink:ChemicalSubstance 7alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36843 CHEBI:36844 biolink:ChemicalSubstance 7-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36844 GO:0070578 biolink:CellularComponent RISC-loading complex A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity. go-plus.json RLC|microRNA loading complex|miRLC http://purl.obolibrary.org/obo/GO_0070578 UBERON:0003436 biolink:AnatomicalEntity shoulder nerve A nerve that is part of a shoulder [Automatically generated definition]. go-plus.json nerve of shoulder http://purl.obolibrary.org/obo/UBERON_0003436 UBERON:0003437 biolink:AnatomicalEntity eyelid nerve A nerve that innervates an eyelid. go-plus.json nerve of blepharon|blepharon nerve|nerve of eyelid|palpebral nerve http://purl.obolibrary.org/obo/UBERON_0003437 GO:0070579 biolink:MolecularActivity methylcytosine dioxygenase activity Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2. Reactome:R-HSA-5221014|Reactome:R-HSA-5220952|Reactome:R-HSA-5220990 go-plus.json http://purl.obolibrary.org/obo/GO_0070579 GO:0070576 biolink:MolecularActivity vitamin D 24-hydroxylase activity Catalysis of the hydroxylation of C-24 of any form of vitamin D. go-plus.json ergocalciferol 24-hydroxylase activity|cholecalciferol 24-hydroxylase activity|vitamin D3 24-hydroxylase activity|calciferol 24-hydroxylase activity|vitamin D2 24-hydroxylase activity http://purl.obolibrary.org/obo/GO_0070576 UBERON:0003434 biolink:AnatomicalEntity wrist nerve A nerve that is part of a wrist [Automatically generated definition]. go-plus.json nerve of wrist|nerve of carpal region|carpal region nerve http://purl.obolibrary.org/obo/UBERON_0003434 UBERON:0003435 biolink:AnatomicalEntity pedal digit nerve A nerve that is part of a toe [Automatically generated definition]. go-plus.json nerve of foot digit|digit of foot nerve|digitus pedis nerve|foot digit nerve|nerve of digit of terminal segment of free lower limb|nerve of terminal segment of free lower limb digit|foot digit nerve|terminal segment of free lower limb digit nerve|digit of terminal segment of free lower limb nerve|nerve of toe|toe nerve|hind limb digit nerve|nerve of digitus pedis|nerve of digit of foot http://purl.obolibrary.org/obo/UBERON_0003435 GO:0070577 biolink:MolecularActivity lysine-acetylated histone binding Binding to a histone in which a lysine residue has been modified by acetylation. go-plus.json acetylated histone residue binding http://purl.obolibrary.org/obo/GO_0070577 GO:0070574 biolink:BiologicalProcess cadmium ion transmembrane transport A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json transmembrane cadmium transport|cadmium ion membrane transport http://purl.obolibrary.org/obo/GO_0070574 UBERON:0003432 biolink:AnatomicalEntity chest nerve A nerve that is part of a chest [Automatically generated definition]. go-plus.json nerve of chest|nerve of front of thorax|nerve of anterior thoracic region|front of thorax nerve|anterior thoracic region nerve|nerve of anterolateral part of thorax|anterolateral part of thorax nerve http://purl.obolibrary.org/obo/UBERON_0003432 GO:0070575 biolink:BiologicalProcess peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation. go-plus.json peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation|peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation http://purl.obolibrary.org/obo/GO_0070575 UBERON:0003433 biolink:AnatomicalEntity arm nerve A nerve that is part of an arm [Automatically generated definition]. go-plus.json nerve of arm|nerve of brachial region|brachial region nerve http://purl.obolibrary.org/obo/UBERON_0003433 GO:0070572 biolink:BiologicalProcess positive regulation of neuron projection regeneration Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. go-plus.json http://purl.obolibrary.org/obo/GO_0070572 UBERON:0003430 biolink:AnatomicalEntity neck nerve A nerve that is part of a neck [Automatically generated definition]. go-plus.json nerve of neck (volume)|nerve of neck|neck (volume) nerve http://purl.obolibrary.org/obo/UBERON_0003430 GO:0070573 biolink:MolecularActivity metallodipeptidase activity Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Reactome:R-HSA-2022405|Reactome:R-HSA-2022398|Reactome:R-HSA-2065355 go-plus.json metallo-exo-dipeptidase activity|metalloexodipeptidase activity http://purl.obolibrary.org/obo/GO_0070573 UBERON:0003431 biolink:AnatomicalEntity leg nerve A nerve that is part of a leg [Automatically generated definition]. go-plus.json nerve of leg http://purl.obolibrary.org/obo/UBERON_0003431 CHEBI:22211 biolink:ChemicalSubstance aconitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_22211 GO:0070560 biolink:BiologicalProcess protein secretion by platelet The regulated release of proteins by a platelet or group of platelets. go-plus.json http://purl.obolibrary.org/obo/GO_0070560 CHEBI:22210 biolink:ChemicalSubstance aconitate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_22210 chebi_ph7_3 UBERON:0003418 biolink:AnatomicalEntity mesenchyme of submandibular gland Mesenchyme that is part of a developing submandibular gland [Automatically generated definition]. go-plus.json submaxillary gland mesenchyme|submandibular gland mesenchyme http://purl.obolibrary.org/obo/UBERON_0003418 CHEBI:22216 biolink:ChemicalSubstance acrylamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_22216 UBERON:0003416 biolink:AnatomicalEntity mesenchyme of tongue Mesenchyme that is part of a developing tongue [Automatically generated definition]. go-plus.json tongue mesenchyme http://purl.obolibrary.org/obo/UBERON_0003416 CHEBI:22213 biolink:ChemicalSubstance acridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_22213 UBERON:0003417 biolink:AnatomicalEntity mesenchyme of soft palate Mesenchyme that is part of a developing soft palate [Automatically generated definition]. go-plus.json soft palate mesenchyme http://purl.obolibrary.org/obo/UBERON_0003417 CHEBI:36859 biolink:ChemicalSubstance 2beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36859 NCBITaxon:2653789 biolink:OrganismalEntity Whippomorpha go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2653789 CHEBI:36852 biolink:ChemicalSubstance 26-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36852 CHEBI:36853 biolink:ChemicalSubstance hydroxy seco-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36853 CHEBI:36850 biolink:ChemicalSubstance 6alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36850 CHEBI:36851 biolink:ChemicalSubstance 6beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36851 CHEBI:36856 biolink:ChemicalSubstance hydrogen isocyanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_36856 CHEBI:36857 biolink:ChemicalSubstance 2-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36857 GO:0070569 biolink:MolecularActivity uridylyltransferase activity Catalysis of the transfer of an uridylyl group to an acceptor. go-plus.json uridyl transferase activity|uridyltransferase activity http://purl.obolibrary.org/obo/GO_0070569 CHEBI:36854 biolink:ChemicalSubstance 20-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36854 CHEBI:36855 biolink:ChemicalSubstance 18-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36855 GO:0070567 biolink:MolecularActivity cytidylyltransferase activity Catalysis of the transfer of a cytidylyl group to an acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070567 UBERON:0003425 biolink:AnatomicalEntity renal lymph node A lymph node that is located in a kidney [Automatically generated definition]. go-plus.json lymph node of kidney|kidney lymph node http://purl.obolibrary.org/obo/UBERON_0003425 UBERON:0003426 biolink:AnatomicalEntity dermis adipose tissue An adipose tissue that is part of a dermis [Automatically generated definition]. go-plus.json dermis fatty tissue|adipose tissue of dermis|fat tissue of dermis|fatty tissue of dermis|dermis fat tissue http://purl.obolibrary.org/obo/UBERON_0003426 GO:0070568 biolink:MolecularActivity guanylyltransferase activity Catalysis of the transfer of a guanylyl group to an acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070568 GO:0070565 biolink:CellularComponent telomere-telomerase complex A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0070565 GO:0070566 biolink:MolecularActivity adenylyltransferase activity Catalysis of the transfer of an adenylyl group to an acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0070566 UBERON:0003424 biolink:AnatomicalEntity mesenchyme of hard palate Mesenchyme that is part of a developing hard palate [Automatically generated definition]. go-plus.json hard palate mesenchyme http://purl.obolibrary.org/obo/UBERON_0003424 GO:0070563 biolink:BiologicalProcess negative regulation of vitamin D receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity. go-plus.json negative regulation of VDR signaling pathway|down-regulation of vitamin D receptor signaling pathway|negative regulation of VDR signalling pathway|downregulation of vitamin D receptor signaling pathway|down regulation of vitamin D receptor signaling pathway|inhibition of vitamin D receptor signaling pathway|negative regulation vitamin D receptor signalling pathway http://purl.obolibrary.org/obo/GO_0070563 GO:0070564 biolink:BiologicalProcess positive regulation of vitamin D receptor signaling pathway Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity. go-plus.json up-regulation of vitamin D receptor signaling pathway|activation of vitamin D receptor signaling pathway|positive regulation of VDR signaling pathway|positive regulation of vitamin D receptor signalling pathway|up regulation of vitamin D receptor signaling pathway|upregulation of vitamin D receptor signaling pathway|stimulation of vitamin D receptor signaling pathway http://purl.obolibrary.org/obo/GO_0070564 UBERON:0003422 biolink:AnatomicalEntity mesenchyme of umbilical cord A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP] go-plus.json umbilical cord mesenchyme|Wharton's jelly http://purl.obolibrary.org/obo/UBERON_0003422 GO:0070561 biolink:BiologicalProcess vitamin D receptor signaling pathway The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands. go-plus.json vitamin D receptor signalling pathway|VDR signaling pathway|calcitriol signaling pathway http://purl.obolibrary.org/obo/GO_0070561 GO:0070562 biolink:BiologicalProcess regulation of vitamin D receptor signaling pathway Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity. go-plus.json regulation of vitamin D receptor signalling pathway|regulation of VDR signaling pathway http://purl.obolibrary.org/obo/GO_0070562 GO:0070592 biolink:BiologicalProcess cell wall polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall. go-plus.json cell wall polysaccharide synthesis|cell wall polysaccharide biosynthesis|cell wall polysaccharide anabolism http://purl.obolibrary.org/obo/GO_0070592 GO:0070593 biolink:BiologicalProcess dendrite self-avoidance The process in which dendrites recognize and avoid contact with sister dendrites from the same cell. go-plus.json dendrite repulsion http://purl.obolibrary.org/obo/GO_0070593 GO:0070590 biolink:BiologicalProcess spore wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore. go-plus.json http://purl.obolibrary.org/obo/GO_0070590 GO:0070591 biolink:BiologicalProcess ascospore wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall. go-plus.json http://purl.obolibrary.org/obo/GO_0070591 CHEBI:36828 biolink:ChemicalSubstance pseudohalide anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36828 CHEBI:36829 biolink:ChemicalSubstance polyatomic monoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36829 UBERON:0003494 biolink:AnatomicalEntity respiratory system venule A venule that is part of a respiratory system [Automatically generated definition]. go-plus.json venule of apparatus respiratorius|venule of respiratory system|apparatus respiratorius venule http://purl.obolibrary.org/obo/UBERON_0003494 UBERON:0003495 biolink:AnatomicalEntity respiratory system arteriole An arteriole that is part of a respiratory system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003495 CHEBI:36820 biolink:ChemicalSubstance ring assembly go-plus.json http://purl.obolibrary.org/obo/CHEBI_36820 CHEBI:36823 biolink:ChemicalSubstance pseudohalo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_36823 GO:0070598 biolink:BiologicalProcess cell wall (1->3)-alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells. go-plus.json cell wall 1,3-alpha-glucan anabolism|cell wall alpha-1,3-glucan anabolism|cell wall alpha-1,3-glucan biosynthetic process|cell wall 1,3-alpha-glucan biosynthesis|cell wall 1,3-alpha-glucan biosynthetic process|cell wall 1,3-alpha-glucan synthesis|cell wall alpha-1,3-glucan synthesis|cell wall alpha-1,3-glucan biosynthesis|cell wall 1,3-alpha-glucan formation|cell wall alpha-1,3-glucan formation http://purl.obolibrary.org/obo/GO_0070598 GO:0070599 biolink:BiologicalProcess fungal-type cell wall (1->3)-alpha-glucan metabolic process The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores. go-plus.json ascospore wall alpha-1,3 glucan metabolic process|ascospore wall alpha-1,3 glucan metabolism|ascospore wall 1,3-alpha-glucan metabolism|ascospore wall 1,3-alpha-glucan metabolic process http://purl.obolibrary.org/obo/GO_0070599 GO:0070596 biolink:BiologicalProcess (1->3)-alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. go-plus.json 1,3-alpha-glucan synthesis|alpha-1,3 glucan biosynthesis|1,3-alpha-glucan formation|alpha-1,3 glucan biosynthetic process|alpha-1,3 glucan anabolism|alpha-1,3 glucan synthesis|1,3-alpha-glucan biosynthetic process|alpha-1,3 glucan formation|1,3-alpha-glucan biosynthesis|1,3-alpha-glucan anabolism http://purl.obolibrary.org/obo/GO_0070596 UBERON:0003498 biolink:AnatomicalEntity heart blood vessel A blood vessel that is part of a heart [Automatically generated definition]. go-plus.json blood vessel of heart|cardiac blood vessel http://purl.obolibrary.org/obo/UBERON_0003498 GO:0070597 biolink:BiologicalProcess cell wall (1->3)-alpha-glucan metabolic process The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. go-plus.json cell wall alpha-1,3 glucan metabolism|cell wall alpha-1,3 glucan metabolic process|cell wall 1,3-alpha-glucan metabolism|cell wall 1,3-alpha-glucan metabolic process http://purl.obolibrary.org/obo/GO_0070597 UBERON:0003499 biolink:AnatomicalEntity brain blood vessel A blood vessel that is part of a brain [Automatically generated definition]. go-plus.json blood vessel of brain http://purl.obolibrary.org/obo/UBERON_0003499 GO:0070594 biolink:MolecularActivity juvenile hormone response element binding Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone. go-plus.json JHRE binding http://purl.obolibrary.org/obo/GO_0070594 UBERON:0003496 biolink:AnatomicalEntity head blood vessel A blood vessel that is part of a head [Automatically generated definition]. go-plus.json adult head blood vessel|blood vessel of adult head|blood vessel of head http://purl.obolibrary.org/obo/UBERON_0003496 GO:0070595 biolink:BiologicalProcess (1->3)-alpha-glucan metabolic process The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. go-plus.json alpha-1,3 glucan metabolic process|alpha-1,3 glucan metabolism|1,3-alpha-glucan metabolic process|1,3-alpha-glucan metabolism http://purl.obolibrary.org/obo/GO_0070595 UBERON:0003497 biolink:AnatomicalEntity abdomen blood vessel A blood vessel that is part of an abdomen [Automatically generated definition]. go-plus.json blood vessel of abdomen http://purl.obolibrary.org/obo/UBERON_0003497 GO:0070581 biolink:BiologicalProcess rolling circle DNA replication A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon. go-plus.json rolling circle replication http://purl.obolibrary.org/obo/GO_0070581 GO:0070582 biolink:BiologicalProcess theta DNA replication A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template. go-plus.json theta replication http://purl.obolibrary.org/obo/GO_0070582 GO:0070580 biolink:BiologicalProcess base J metabolic process The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J. go-plus.json beta-D-glucosyl-hydroxymethyluracil metabolism|beta-D-glucosyl-HOMedU metabolic process|base J metabolism http://purl.obolibrary.org/obo/GO_0070580 CHEBI:36838 biolink:ChemicalSubstance 17-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36838 CHEBI:36836 biolink:ChemicalSubstance 3beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36836 chebi_ph7_3 UBERON:0003483 biolink:AnatomicalEntity thymus lymphoid tissue A portion of lymphoid tissue that is part of a thymus [Automatically generated definition]. go-plus.json lymphoid tissue of thymus gland|thymus gland lymphoid tissue|lymphoid tissue of thymus http://purl.obolibrary.org/obo/UBERON_0003483 CHEBI:36830 biolink:ChemicalSubstance monoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_36830 UBERON:0003484 biolink:AnatomicalEntity eye sebaceous gland A sebaceous gland that is part of a camera-type eye. Example: a tarsal gland. go-plus.json sebaceous gland of vertebrate eye|vertebrate eye sebaceous gland|camera-type eye sebaceous gland|sebaceous gland of camera-type eye http://purl.obolibrary.org/obo/UBERON_0003484 UBERON:0003481 biolink:AnatomicalEntity tail vein A vein that is part of a tail [Automatically generated definition]. go-plus.json vein of post-vent region|vein of tail|post-vent region vein|caudal vein http://purl.obolibrary.org/obo/UBERON_0003481 UBERON:0003482 biolink:AnatomicalEntity vein of trabecular bone A portion of vein that is part of a trabecular bone tissue [Automatically generated definition]. go-plus.json trabecular bone tissue vein|vein of trabecular bone tissue|spongy bone vein|vein of spongy bone|trabecular bone vein http://purl.obolibrary.org/obo/UBERON_0003482 CHEBI:36834 biolink:ChemicalSubstance 3-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36834 UBERON:0003480 biolink:AnatomicalEntity vein of clitoris A vein that is part of a clitoris [Automatically generated definition]. go-plus.json clitoris vein http://purl.obolibrary.org/obo/UBERON_0003480 CHEBI:36835 biolink:ChemicalSubstance 3alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_36835 chebi_ph7_3 GO:0070589 biolink:BiologicalProcess cellular component macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component. go-plus.json cellular component macromolecule biosynthesis http://purl.obolibrary.org/obo/GO_0070589 NCBITaxon:57678 biolink:OrganismalEntity Leptospira interrogans serovar Lai go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_57678 UBERON:0003489 biolink:AnatomicalEntity respiratory system capillary endothelium An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. go-plus.json apparatus respiratorius endothelium of blood capillary|blood capillary endothelium of apparatus respiratorius|endothelium of capillary vessel of apparatus respiratorius|respiratory system capillary vessel endothelium|capillary endothelium of respiratory system|respiratory system endothelium of capillary|capillary endothelium of apparatus respiratorius|endothelium of capillary vessel of respiratory system|blood capillary endothelium of respiratory system|respiratory system endothelium of blood capillary|respiratory system endothelium of capillary vessel|capillary vessel endothelium of respiratory system|endothelium of capillary of respiratory system|endothelium of blood capillary of apparatus respiratorius|respiratory system blood capillary endothelium|endothelium of blood capillary of respiratory system|apparatus respiratorius capillary endothelium|endothelium of capillary of apparatus respiratorius|apparatus respiratorius capillary vessel endothelium|capillary vessel endothelium of apparatus respiratorius|apparatus respiratorius endothelium of capillary|apparatus respiratorius endothelium of capillary vessel|apparatus respiratorius blood capillary endothelium http://purl.obolibrary.org/obo/UBERON_0003489 GO:0070587 biolink:BiologicalProcess regulation of cell-cell adhesion involved in gastrulation Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0070587 GO:0070588 biolink:BiologicalProcess calcium ion transmembrane transport A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json calcium ion membrane transport|transmembrane calcium transport http://purl.obolibrary.org/obo/GO_0070588 UBERON:0003487 biolink:AnatomicalEntity skin sebaceous gland A holocrine gland of the dermis that secretes sebum into hair follicles. go-plus.json sebaceous gland of skin|cutaneous sebaceous gland http://purl.obolibrary.org/obo/UBERON_0003487 GO:0070585 biolink:BiologicalProcess protein localization to mitochondrion A process in which a protein is transported to, or maintained in, a location within the mitochondrion. go-plus.json protein localisation in mitochondrion|protein localization in mitochondrion http://purl.obolibrary.org/obo/GO_0070585 UBERON:0003488 biolink:AnatomicalEntity abdominal mammary gland A lactiferous gland that is part of the abdominal region [Automatically generated definition]. go-plus.json abdomen lobe of breast|lactiferous gland of abdomen|abdomen mammary gland|lobe of mammary gland of abdomen|lobe of breast of abdomen|abdomen lobe of mammary gland|mammary gland of abdomen|abdomen lactiferous gland http://purl.obolibrary.org/obo/UBERON_0003488 GO:0070586 biolink:BiologicalProcess cell-cell adhesion involved in gastrulation The attachment of one cell to another cell affecting gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0070586 UBERON:0003485 biolink:AnatomicalEntity vagina sebaceous gland A sebaceous gland that is part of a vagina [Automatically generated definition]. go-plus.json sebaceous gland of vagina http://purl.obolibrary.org/obo/UBERON_0003485 GO:0070583 biolink:BiologicalProcess spore membrane bending pathway The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore. go-plus.json FSM bending|ascospore-type prospore membrane bending|forespore membrane bending http://purl.obolibrary.org/obo/GO_0070583 GO:0070584 biolink:BiologicalProcess mitochondrion morphogenesis The process in which the anatomical structures of a mitochondrion are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0070584 CHEBI:36807 biolink:ChemicalSubstance hydrochloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_36807 UBERON:0003472 biolink:AnatomicalEntity cerebellar artery An artery that supplies blood to the cerebellum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003472 UBERON:0003473 biolink:AnatomicalEntity thoracic cavity artery An artery that is part of a thoracic cavity[cjm]. go-plus.json thoracic artery http://purl.obolibrary.org/obo/UBERON_0003473 CHEBI:12875 biolink:ChemicalSubstance trans-2-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12875 chebi_ph7_3 UBERON:0003470 biolink:AnatomicalEntity artery of upper lip The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose. go-plus.json ramus labialis superior arteriae facialis|superior labial artery|arteria labialis superior|superior labial branch of facial artery http://purl.obolibrary.org/obo/UBERON_0003470 CHEBI:12876 biolink:ChemicalSubstance trans-4-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_12876 chebi_ph7_3 UBERON:0003471 biolink:AnatomicalEntity artery of lower lip The Iinferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. go-plus.json ramus labialis inferior arteriae facialis|inferior labial artery|inferior labial branch of facial artery|arteria labialis inferior|ramus labialis inferior (arteria facialis) http://purl.obolibrary.org/obo/UBERON_0003471 UBERON:0003478 biolink:AnatomicalEntity vein of lower lip The inferior labial vein is the vein receiving blood from the lower lip. go-plus.json lower lip vein|venae labiales inferiores|vena labialis inferior|inferior labial vein http://purl.obolibrary.org/obo/UBERON_0003478 UBERON:0003479 biolink:AnatomicalEntity thoracic cavity vein A vein that is part of a thoracic cavity [Automatically generated definition]. go-plus.json cavity of thorax vein|vein of thoracic cavity|vein of cavity of chest|vein of pectoral cavity|chest cavity vein|pectoral cavity vein|vein of chest cavity|cavity of chest vein|vein of cavity of thorax http://purl.obolibrary.org/obo/UBERON_0003479 UBERON:0003476 biolink:AnatomicalEntity respiratory system venous blood vessel A vein that is part of a respiratory system [Automatically generated definition]. go-plus.json vein of respiratory system|vein of apparatus respiratorius|apparatus respiratorius vein|respiratory system vein http://purl.obolibrary.org/obo/UBERON_0003476 UBERON:0003477 biolink:AnatomicalEntity vein of upper lip The inferior labial vein is the vein receiving blood from the upper lip. go-plus.json vena labialis superior|upper lip vein|superior labial vein http://purl.obolibrary.org/obo/UBERON_0003477 UBERON:0003474 biolink:AnatomicalEntity meningeal artery One of the arteries supplying a meninix[Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003474 UBERON:0003475 biolink:AnatomicalEntity ureteric vein A vein that is part of a ureter [Automatically generated definition]. go-plus.json ureter vein|vein of ureter http://purl.obolibrary.org/obo/UBERON_0003475 CHEBI:36816 biolink:ChemicalSubstance oxime O-ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_36816 CHEBI:36818 biolink:ChemicalSubstance seco-cholestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36818 CHEBI:36819 biolink:ChemicalSubstance seco-ergostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_36819 UBERON:0003461 biolink:AnatomicalEntity shoulder bone A bone that is connected via a shoulder joint (i.e. glenohumeral or acromioclavicular joints). The shoulder bones are the clavicle, scapula and humerus - but note that these are only considered to be shoulder bones when a true shoulder is present, as in most tetrapods. go-plus.json bone of shoulder|shoulder-articulating bone http://purl.obolibrary.org/obo/UBERON_0003461 UBERON:0003462 biolink:AnatomicalEntity facial bone A bone that is part of a facial skeleton [Automatically generated definition]. go-plus.json facial bone|bone of facial skeleton|bone of viscerocranium|facial skeleton bone|viscerocranium bone http://purl.obolibrary.org/obo/UBERON_0003462 UBERON:0003460 biolink:AnatomicalEntity arm bone A bone that is part of the region of the forelimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia go-plus.json bone of arm|bone of upper extremity|bone organ of arm|arm bone organ http://purl.obolibrary.org/obo/UBERON_0003460 CHEBI:36810 biolink:ChemicalSubstance (trifluoromethyl)benzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_36810 chebi_ph7_3 UBERON:0003469 biolink:AnatomicalEntity respiratory system artery An artery that is part of a respiratory system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0003469 UBERON:0003468 biolink:AnatomicalEntity ureteric segment of renal artery The ureteral branches of renal artery are small branches which supply the ureter. go-plus.json ureteric artery http://purl.obolibrary.org/obo/UBERON_0003468 UBERON:0003466 biolink:AnatomicalEntity forelimb zeugopod bone A bone that is part of a lower arm [Automatically generated definition]. go-plus.json zeugopod bone, forelimb|arm zeugopod bone|antebrachial region bone|lower arm bone|wing zeugopod bone|arm zeugopod bone organ|zeugopod bone, upper|antebrachial region bone organ http://purl.obolibrary.org/obo/UBERON_0003466 UBERON:0003463 biolink:AnatomicalEntity trunk bone A bone that is part of a trunk [Automatically generated definition]. go-plus.json bone organ of trunk|bone organ of torso|torso bone|bone of trunk|bone of torso|torso bone organ|trunk bone organ http://purl.obolibrary.org/obo/UBERON_0003463 UBERON:0003464 biolink:AnatomicalEntity hindlimb bone A bone that is part of a hindlimb region. Examples: any pes phalanx, femur. Counter-examples: ischium, pubis (they are part of the pelvic girdle) go-plus.json bone organ of lower extremity|bone of hindlimb|bone of inferior member|bone of hind limb|hindlimb bone organ|hind limb bone|bone of lower extremity|bone organ of hindlimb|bone organ of hind limb|hind limb bone organ http://purl.obolibrary.org/obo/UBERON_0003464 CHEBI:76801 biolink:ChemicalSubstance narbomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76801 chebi_ph7_3 GO:1990630 biolink:CellularComponent IRE1-RACK1-PP2A complex A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A. go-plus.json IRE1alpha-RACK1-PP2A complex|ERN1-RACK1-PP2A complex http://purl.obolibrary.org/obo/GO_1990630 CHEBI:27879 biolink:ChemicalSubstance 6-methylpretetramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27879 CHEBI:76802 biolink:ChemicalSubstance 5-O-beta-D-mycaminosyltylactone(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76802 chebi_ph7_3 GO:1990631 biolink:MolecularActivity ErbB-4 class receptor binding Binding to the protein-tyrosine kinase receptor ErbB-4/HER4. go-plus.json HER4 receptor binding http://purl.obolibrary.org/obo/GO_1990631 GO:1990632 biolink:BiologicalProcess branching involved in submandibular gland morphogenesis The process in which the branching structure of the submandibular gland is generated and organized. go-plus.json submandibular gland branching morphogenesis|submandibular gland ductal branching http://purl.obolibrary.org/obo/GO_1990632 CHEBI:52837 biolink:ChemicalSubstance quinolinium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_52837 CHEBI:76800 biolink:ChemicalSubstance pikromycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76800 chebi_ph7_3 UBERON:0010260 biolink:AnatomicalEntity umbilical blood vessel One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta. go-plus.json allantoic vessel|umbilical cord blood vessel|umbilical vasculature|umbilical vessel|umbilical cord blood vessels http://purl.obolibrary.org/obo/UBERON_0010260 CHEBI:52831 biolink:ChemicalSubstance Delta(11)-fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52831 CHEBI:76803 biolink:ChemicalSubstance 5-O-beta-D-mycaminosyl-20-oxotylonolide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76803 chebi_ph7_3 CHEBI:27877 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27877 CHEBI:76804 biolink:ChemicalSubstance 5-O-mycaminosyltylonolide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76804 chebi_ph7_3 CHEBI:76809 biolink:ChemicalSubstance EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76809 CHEBI:27871 biolink:ChemicalSubstance chloroacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27871 chebi_ph7_3 CHEBI:76807 biolink:ChemicalSubstance EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76807 CHEBI:76808 biolink:ChemicalSubstance EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76808 CHEBI:52839 biolink:ChemicalSubstance acridinium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_52839 UBERON:0010258 biolink:AnatomicalEntity mesenchyme from rhombencephalic neural crest Mesenchyme that develops_from a rhombencephalon neural crest. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010258 UBERON:0010259 biolink:AnatomicalEntity 1st arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme. go-plus.json mesenchyme derived from neural crest of mesenchyme of 1st arch|branchial arch 1 mesenchyme from neural crest|pharyngeal arch 1 mesenchyme from neural crest|neural crest derived arch 1 mesenchyme http://purl.obolibrary.org/obo/UBERON_0010259 GO:1990637 biolink:BiologicalProcess response to prolactin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation. go-plus.json http://purl.obolibrary.org/obo/GO_1990637 GO:1990638 biolink:BiologicalProcess response to granulocyte colony-stimulating factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus. go-plus.json response to G-CSF http://purl.obolibrary.org/obo/GO_1990638 GO:1990639 biolink:MolecularActivity obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate. go-plus.json inositol-3,4,5-trisphosphate 5-phosphatase activity http://purl.obolibrary.org/obo/GO_1990639 GO:1990633 biolink:CellularComponent mutator focus A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules. go-plus.json http://purl.obolibrary.org/obo/GO_1990633 GO:1990634 biolink:MolecularActivity protein phosphatase 5 binding Binding to protein phosphatase 5. go-plus.json protein phosphatase T binding http://purl.obolibrary.org/obo/GO_1990634 GO:1990635 biolink:CellularComponent proximal dendrite The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma). go-plus.json http://purl.obolibrary.org/obo/GO_1990635 GO:1990636 biolink:BiologicalProcess reproductive senescence A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones. go-plus.json http://purl.obolibrary.org/obo/GO_1990636 CHEBI:76812 biolink:ChemicalSubstance EC 2.7.11.* (protein-serine/threonine kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76812 GO:1990640 biolink:MolecularActivity inositol-2,4,5-triphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990640 GO:1990641 biolink:BiologicalProcess response to iron ion starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion. go-plus.json http://purl.obolibrary.org/obo/GO_1990641 GO:1990642 biolink:BiologicalProcess obsolete response to castration OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a castration stimulus, deprivation of gonads. go-plus.json response to castration http://purl.obolibrary.org/obo/GO_1990642 CHEBI:76810 biolink:ChemicalSubstance demethyllactenocin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76810 chebi_ph7_3 GO:1990643 biolink:BiologicalProcess cellular response to granulocyte colony-stimulating factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990643 CHEBI:76811 biolink:ChemicalSubstance EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76811 CHEBI:76816 biolink:ChemicalSubstance EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76816 CHEBI:76817 biolink:ChemicalSubstance EC 2.7.10.* (protein-tyrosine kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76817 CHEBI:76814 biolink:ChemicalSubstance dTDP-beta-L-mycarose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76814 chebi_ph7_3 CHEBI:27887 biolink:ChemicalSubstance 6-phospho-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27887 CHEBI:27888 biolink:ChemicalSubstance chlorophyll b go-plus.json http://purl.obolibrary.org/obo/CHEBI_27888 CHEBI:76815 biolink:ChemicalSubstance EC 2.7.7.* (nucleotidyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76815 UBERON:0010252 biolink:AnatomicalEntity 1st arch mandibular mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010252 CHEBI:27881 biolink:ChemicalSubstance resveratrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27881 chebi_ph7_3 UBERON:0010253 biolink:AnatomicalEntity 1st arch maxillary mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010253 CHEBI:76819 biolink:ChemicalSubstance demethylmacrocin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76819 chebi_ph7_3 CHEBI:27884 biolink:ChemicalSubstance D-fructofuranose 2-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27884 UBERON:0010256 biolink:AnatomicalEntity 4th arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. go-plus.json 4th pharyngeal arch mesenchyme derived from neural crest|mesenchyme derived from neural crest of mesenchyme of 4th arch|branchial arch 4 mesenchyme from neural crest|pharyngeal arch 4 mesenchyme from neural crest|neural crest derived arch 4 mesenchyme http://purl.obolibrary.org/obo/UBERON_0010256 UBERON:0010257 biolink:AnatomicalEntity 6th arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. go-plus.json neural crest derived arch 6 mesenchyme|pharyngeal arch 6 mesenchyme from neural crest|branchial arch 6 mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010257 UBERON:0010254 biolink:AnatomicalEntity 2nd arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme. go-plus.json branchial arch 2 mesenchyme from neural crest|pharyngeal arch 2 mesenchyme from neural crest|neural crest derived arch 2 mesenchyme http://purl.obolibrary.org/obo/UBERON_0010254 UBERON:0010255 biolink:AnatomicalEntity 3rd arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme. go-plus.json 3rd pharyngeal arch mesenchyme derived from neural crest|mesenchyme derived from neural crest of mesenchyme of 3rd arch|branchial arch 3 mesenchyme from neural crest|pharyngeal arch 3 mesenchyme from neural crest|neural crest derived arch 3 mesenchyme http://purl.obolibrary.org/obo/UBERON_0010255 CHEBI:37205 biolink:ChemicalSubstance pentol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37205 CHEBI:37208 biolink:ChemicalSubstance pinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37208 CHEBI:37209 biolink:ChemicalSubstance L-pinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37209 chebi_ph7_3 CHEBI:37206 biolink:ChemicalSubstance hexol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37206 CHEBI:37207 biolink:ChemicalSubstance cis-3-dodecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37207 GO:1990648 biolink:MolecularActivity inositol-4,5,6-triphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990648 GO:1990649 biolink:MolecularActivity inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990649 GO:1990644 biolink:MolecularActivity microtubule site clamp The binding activity of a molecule that attaches the spindle microtubules to the kinetochore. go-plus.json http://purl.obolibrary.org/obo/GO_1990644 GO:1990645 biolink:BiologicalProcess obsolete phosphorylase dephosphorylation OBSOLETE. The modification of phosphorylases by removal of phosphate groups. go-plus.json phosphorylase dephosphorylation http://purl.obolibrary.org/obo/GO_1990645 GO:1990646 biolink:BiologicalProcess cellular response to prolactin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990646 GO:1990647 biolink:CellularComponent C/EBP complex A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities. go-plus.json C/EBPbeta homodimer complex|C/EBPalpha homodimer complex|C/EBPalpha complex|C/EBPbeta complex|C/EBP transcription factor complex|C/EBP homodimer complex http://purl.obolibrary.org/obo/GO_1990647 GO:1990651 biolink:MolecularActivity inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990651 CHEBI:27856 biolink:ChemicalSubstance acetamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27856 chebi_ph7_3 CHEBI:76823 biolink:ChemicalSubstance EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76823 CHEBI:76824 biolink:ChemicalSubstance EC 6.4.1.* (carboxylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76824 GO:1990652 biolink:BiologicalProcess obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage. go-plus.json positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1990652 CHEBI:27857 biolink:ChemicalSubstance (1->4)-beta-D-mannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27857 chebi_ph7_3 GO:1990653 biolink:BiologicalProcess obsolete monounsaturated fatty acid biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids. go-plus.json http://purl.obolibrary.org/obo/GO_1990653 CHEBI:76821 biolink:ChemicalSubstance beta-D-Manp-(1->4)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_76821 chebi_ph7_3 CHEBI:27858 biolink:ChemicalSubstance precorrin-6Y go-plus.json http://purl.obolibrary.org/obo/CHEBI_27858 CHEBI:27859 biolink:ChemicalSubstance S-methyl-5-thio-alpha-D-ribose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27859 GO:1990654 biolink:BiologicalProcess sebum secreting cell proliferation The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum. go-plus.json sebocyte proliferation http://purl.obolibrary.org/obo/GO_1990654 CHEBI:27852 biolink:ChemicalSubstance 3,4-dihydroxymandelaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27852 chebi_ph7_3 CHEBI:76825 biolink:ChemicalSubstance cellobionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76825 chebi_ph7_3 GO:1990650 biolink:MolecularActivity inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990650 CHEBI:27855 biolink:ChemicalSubstance L-erythro-3-methylmalyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27855 CHEBI:76829 biolink:ChemicalSubstance EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76829 CHEBI:27851 biolink:ChemicalSubstance keto-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27851 UBERON:0010243 biolink:AnatomicalEntity merocrine gland An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010243 CHEBI:13248 biolink:ChemicalSubstance anilide go-plus.json http://purl.obolibrary.org/obo/CHEBI_13248 chebi_ph7_3 GO:1990659 biolink:BiologicalProcess sequestering of manganese ion The process of binding or confining manganese ions such that they are separated from other components of a biological system. go-plus.json sequestration of manganese ion|manganese ion retention|storage of manganese ion|manganese ion sequestering|manganese ion storage|retention of manganese ion|manganese ion sequestration http://purl.obolibrary.org/obo/GO_1990659 GO:1990655 biolink:MolecularActivity 4 iron, 3 sulfur cluster binding Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria. go-plus.json 4Fe-3S cluster binding http://purl.obolibrary.org/obo/GO_1990655 GO:1990656 biolink:BiologicalProcess t-SNARE clustering The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies. go-plus.json http://purl.obolibrary.org/obo/GO_1990656 CHEBI:76820 biolink:ChemicalSubstance macrocin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76820 chebi_ph7_3 GO:1990657 biolink:CellularComponent iNOS-S100A8/A9 complex A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_1990657 GO:1990658 biolink:CellularComponent transnitrosylase complex A transferase complex which is capable of transferring nitrogenous groups from one component to another. go-plus.json transferase complex, transferring nitrogenous groups http://purl.obolibrary.org/obo/GO_1990658 CHEBI:27867 biolink:ChemicalSubstance antheraxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27867 chebi_ph7_3 GO:1990662 biolink:CellularComponent S100A9 complex A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility. go-plus.json S100A9 homodimer http://purl.obolibrary.org/obo/GO_1990662 CHEBI:76834 biolink:ChemicalSubstance EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76834 GO:1990663 biolink:MolecularActivity dihydroorotate dehydrogenase (fumarate) activity Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate. RHEA:30059|EC:1.3.98.1 go-plus.json http://purl.obolibrary.org/obo/GO_1990663 CHEBI:76835 biolink:ChemicalSubstance EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76835 CHEBI:27868 biolink:ChemicalSubstance 3-oxolauroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27868 GO:1990664 biolink:CellularComponent Nkx-2.5 complex A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. go-plus.json NKX2.5 complex|Nkx-2.5 homodimer complex|NKX2E homodimer complex|NKX.2-5 homodimer complex http://purl.obolibrary.org/obo/GO_1990664 CHEBI:76832 biolink:ChemicalSubstance EC 4.3.1.* (ammonia-lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76832 CHEBI:27869 biolink:ChemicalSubstance chloroacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27869 GO:1990665 biolink:CellularComponent AnxA2-p11 complex A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10). go-plus.json Annexin A2 tetramer|(p11)2.(AnxA2)2 complex|(A2.p11)2 complex|AnxA2:S100A10 heterotetramer|Annexin A2-p11 complex|AnxA2.p11 complex http://purl.obolibrary.org/obo/GO_1990665 CHEBI:76838 biolink:ChemicalSubstance EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76838 CHEBI:76839 biolink:ChemicalSubstance dTDP-beta-L-vancosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76839 chebi_ph7_3 GO:1990660 biolink:CellularComponent calprotectin complex A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. go-plus.json calprotectin heterodimer http://purl.obolibrary.org/obo/GO_1990660 CHEBI:27865 biolink:ChemicalSubstance fucosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27865 chebi_ph7_3 CHEBI:76836 biolink:ChemicalSubstance EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76836 GO:1990661 biolink:CellularComponent S100A8 complex A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4). go-plus.json S100A8 homodimer http://purl.obolibrary.org/obo/GO_1990661 CHEBI:76837 biolink:ChemicalSubstance EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76837 UBERON:0010230 biolink:AnatomicalEntity eyeball of camera-type eye The core globe-shaped component of the camera-type eye. go-plus.json eyeball|eye|globe|bulbus oculi|eye globe http://purl.obolibrary.org/obo/UBERON_0010230 UBERON:0010231 biolink:AnatomicalEntity anatomical line between outer ears go-plus.json otic line|inter-otic line|inter-pinna line http://purl.obolibrary.org/obo/UBERON_0010231 UBERON:0010233 biolink:AnatomicalEntity stroma of thyroid gland The connective tissue that supports the lobules and follicles of the thyroid gland. go-plus.json thyroid gland stroma|thyroid stroma http://purl.obolibrary.org/obo/UBERON_0010233 UBERON:0010227 biolink:AnatomicalEntity future cardiac atrium Multi-tissue structure that is part of the heart tube and will become the cardiac atrium. go-plus.json primordial cardiac atrium|primordial atrium|presumptive atrium heart tube http://purl.obolibrary.org/obo/UBERON_0010227 UBERON:0010225 biolink:AnatomicalEntity thalamic complex A nuclear complex which in mammals consists of four parts, the hypothalamus, epithalamus, ventral thalamus, and dorsal thalamus[WP,modified]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010225 GO:1990666 biolink:CellularComponent PCSK9-LDLR complex A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway. go-plus.json PCSK9/LDL-R complex|PCSK9:low-density lipoprotein receptor complex|PCSK9:EGF-A complex|PCSK9.LDLR complex http://purl.obolibrary.org/obo/GO_1990666 CHEBI:76830 biolink:ChemicalSubstance EC 5.99.1.* (miscellaneous isomerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76830 GO:1990667 biolink:CellularComponent PCSK9-AnxA2 complex A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and annexin A2 (AnxA2). go-plus.json PCSK9-Annexin A2 complex|PCSK9.AnxA2 complex|PCSK9:ANXA2 complex http://purl.obolibrary.org/obo/GO_1990667 CHEBI:76831 biolink:ChemicalSubstance EC 4.4.1.* (C-S lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76831 GO:1990668 biolink:BiologicalProcess vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles. go-plus.json vesicle fusion with ER-Golgi intermediate compartment membrane|vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment membrane|vesicle fusion with ERGIC membrane|vesicle fusion with ER-Golgi intermediate compartment (ERGIC) membrane http://purl.obolibrary.org/obo/GO_1990668 GO:1990669 biolink:BiologicalProcess endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. go-plus.json ER-Golgi intermediate compartment derived vesicle fusion with ER membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with ER membrane http://purl.obolibrary.org/obo/GO_1990669 CHEBI:76845 biolink:ChemicalSubstance EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76845 CHEBI:76846 biolink:ChemicalSubstance 7-deoxyloganetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76846 chebi_ph7_3 CHEBI:27836 biolink:ChemicalSubstance dodecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_27836 chebi_ph7_3 CHEBI:76844 biolink:ChemicalSubstance 7-deoxyloganate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76844 chebi_ph7_3 CHEBI:76849 biolink:ChemicalSubstance 7-deoxyloganetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_76849 chebi_ph7_3 CHEBI:76847 biolink:ChemicalSubstance EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76847 CHEBI:76848 biolink:ChemicalSubstance EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76848 CHEBI:62200 biolink:ChemicalSubstance galactosyl-(glucosyl)2-(heptosyl)3-(KDO)2-lipid A-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62200 CHEBI:62201 biolink:ChemicalSubstance galactosyl-glucosyl-heptosyl-(phosphoheptosyl)2-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_62201 CHEBI:62205 biolink:ChemicalSubstance 3-methylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62205 CHEBI:62202 biolink:ChemicalSubstance glucosyl-heptosyl-(phosphoheptosyl)2-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_62202 CHEBI:62203 biolink:ChemicalSubstance glucosyl-(heptosyl)2-4-phosphoheptosyl-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_62203 CHEBI:62208 biolink:ChemicalSubstance 3-methyl-7H-xanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62208 chebi_ph7_3 CHEBI:62209 biolink:ChemicalSubstance CoA-disulfide(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62209 chebi_ph7_3 CHEBI:62206 biolink:ChemicalSubstance monomethylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62206 CHEBI:62207 biolink:ChemicalSubstance 3-methyl-9H-xanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62207 chebi_ph7_3 CHEBI:76841 biolink:ChemicalSubstance EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76841 CHEBI:76842 biolink:ChemicalSubstance vancomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76842 chebi_ph7_3 CHEBI:76840 biolink:ChemicalSubstance EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76840 CHEBI:76856 biolink:ChemicalSubstance 3-(5-oxoisoxazolin-4-yl)-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76856 chebi_ph7_3 CHEBI:76857 biolink:ChemicalSubstance EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76857 CHEBI:27847 biolink:ChemicalSubstance 3-iodo-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27847 CHEBI:27848 biolink:ChemicalSubstance alpha-L-rhamnoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27848 chebi_ph7_3 CHEBI:76855 biolink:ChemicalSubstance 3-(5-oxoisoxazolin-2-yl)-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76855 chebi_ph7_3 CHEBI:27843 biolink:ChemicalSubstance cyanidin cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_27843 CHEBI:27844 biolink:ChemicalSubstance 2',3'-cyclic AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_27844 UBERON:0010291 biolink:AnatomicalEntity layer of sclera . go-plus.json http://purl.obolibrary.org/obo/UBERON_0010291 UBERON:0010294 biolink:AnatomicalEntity scleral endothelium An endothelium that is part of a sclera. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010294 UBERON:0010295 biolink:AnatomicalEntity substantia propria of sclera A stroma that is part of a sclera. go-plus.json subsantia propria|subsantia propria sclerae|scleral stroma|stroma of sclera|substantia propria sclerae http://purl.obolibrary.org/obo/UBERON_0010295 CHEBI:62211 biolink:ChemicalSubstance 3-butynoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62211 chebi_ph7_3 CHEBI:62212 biolink:ChemicalSubstance 5-hydroxypyrrole-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62212 CHEBI:62210 biolink:ChemicalSubstance 5-hydroxypyrrole-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62210 chebi_ph7_3 UBERON:0010299 biolink:AnatomicalEntity scleral mesenchyme Mesenchyme surrounding the developing optic cup which develops into the sclera. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010299 CHEBI:62215 biolink:ChemicalSubstance allelochemical go-plus.json http://purl.obolibrary.org/obo/CHEBI_62215 CHEBI:62216 biolink:ChemicalSubstance 1-hydroxyphenazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62216 chebi_ph7_3 CHEBI:62213 biolink:ChemicalSubstance D-4-hydroxy-2-oxoglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62213 chebi_ph7_3 CHEBI:62214 biolink:ChemicalSubstance 5-hydroxykynurenaminium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62214 chebi_ph7_3 GO:1990608 biolink:BiologicalProcess mitotic spindle pole body localization A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location. go-plus.json spindle pole body localisation in nuclear envelope|establishment and maintenance of spindle pole body localization|spindle pole body localization in nuclear envelope|establishment of spindle pole body localisation|establishment of spindle pole body localization|spindle pole body positioning|mitotic spindle pole body localization to nuclear envelope|spindle pole body docking|spindle pole body localization to nuclear envelope http://purl.obolibrary.org/obo/GO_1990608 CHEBI:62219 biolink:ChemicalSubstance 2-heptyl-4-quinolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_62219 chebi_ph7_3 GO:1990609 biolink:MolecularActivity glutamate-cysteine ligase regulator activity Binds to and modulates the activity of glutamate-cysteine ligase. go-plus.json http://purl.obolibrary.org/obo/GO_1990609 CHEBI:62217 biolink:ChemicalSubstance 23,24-dihydrocucurbitacin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_62217 chebi_ph7_3 GO:1990604 biolink:CellularComponent IRE1-TRAF2-ASK1 complex A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K). go-plus.json ERN1-TRAF2-ASK1 complex http://purl.obolibrary.org/obo/GO_1990604 GO:1990605 biolink:MolecularActivity GU repeat RNA binding Binding to an RNA molecule containing GU repeats. go-plus.json http://purl.obolibrary.org/obo/GO_1990605 GO:1990606 biolink:MolecularActivity membrane scission GTPase motor activity Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_1990606 GO:1990607 biolink:BiologicalProcess obsolete detection of stimulus involved in cytokinesis after mitosis checkpoint OBSOLETE. The series of events in which information about whether cytokinesis has correctly completed, is received and converted into a molecular signal, contributing to a cytokinesis after mitosis checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_1990607 GO:1990600 biolink:MolecularActivity single-stranded DNA endodeoxyribonuclease activator activity Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity. go-plus.json http://purl.obolibrary.org/obo/GO_1990600 CHEBI:76852 biolink:ChemicalSubstance EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76852 CHEBI:27849 biolink:ChemicalSubstance toluene-4-sulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27849 GO:1990601 biolink:MolecularActivity 5' overhang single-stranded DNA endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks. go-plus.json http://purl.obolibrary.org/obo/GO_1990601 CHEBI:76853 biolink:ChemicalSubstance EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76853 GO:1990602 biolink:CellularComponent obsolete importin alpha-subunit nuclear import complex OBSOLETE. A trimeric protein complex which functions to transport the importin alpha-subunit into the nucleus through the nuclear pore to facilitate another round of mRNP incorporation and regulation. In Drosophila it consists of Cdm (Imp13), Mago and Tsu (Y14). go-plus.json Importin13-Mago-Tsu complex|Cdm-Mago-Tsu complex http://purl.obolibrary.org/obo/GO_1990602 GO:1990603 biolink:BiologicalProcess dark adaptation The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light. go-plus.json http://purl.obolibrary.org/obo/GO_1990603 CHEBI:76851 biolink:ChemicalSubstance isoxazolin-5-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_76851 chebi_ph7_3 CHEBI:27812 biolink:ChemicalSubstance Se-methyl-L-selenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27812 CHEBI:27814 biolink:ChemicalSubstance 12-dehydro-leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27814 GO:1990610 biolink:MolecularActivity acetolactate synthase regulator activity Binds to and modulates the activity of acetolactate synthase. go-plus.json http://purl.obolibrary.org/obo/GO_1990610 CHEBI:76866 biolink:ChemicalSubstance EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76866 UBERON:0009292 biolink:AnatomicalEntity embryonic nasal process go-plus.json nasal placode http://purl.obolibrary.org/obo/UBERON_0009292 CHEBI:76869 biolink:ChemicalSubstance EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76869 CHEBI:27810 biolink:ChemicalSubstance resorcinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27810 chebi_ph7_3 CHEBI:27811 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27811 UBERON:0010285 biolink:AnatomicalEntity midbrain basal plate Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. go-plus.json basal plate midbrain|basal plate midbrain region http://purl.obolibrary.org/obo/UBERON_0010285 UBERON:0010286 biolink:AnatomicalEntity midbrain neural tube Portion of neural tube that gives rise to the midbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010286 CHEBI:62222 biolink:ChemicalSubstance 4-methyl-3-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62222 chebi_ph7_3 CHEBI:13209 biolink:ChemicalSubstance long-chain fatty acid ethyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_13209 chebi_ph7_3 CHEBI:62223 biolink:ChemicalSubstance 2-(beta-D-glucosyloxy)-cis-cinnamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62223 chebi_ph7_3 CHEBI:62220 biolink:ChemicalSubstance pyocyanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62220 chebi_ph7_3 CHEBI:62221 biolink:ChemicalSubstance 5-methylphenazine-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62221 chebi_ph7_3 CHEBI:62226 biolink:ChemicalSubstance L-selenocystathionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62226 chebi_ph7_3 CHEBI:62227 biolink:ChemicalSubstance L-adenosylselenomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62227 chebi_ph7_3 CHEBI:62224 biolink:ChemicalSubstance (-)-7-epi-alpha-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62224 chebi_ph7_3 CHEBI:62225 biolink:ChemicalSubstance S-sulfo-L-cysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62225 chebi_ph7_3 GO:1990619 biolink:BiologicalProcess histone H3-K9 deacetylation The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_1990619 GO:1990615 biolink:CellularComponent Kelch-containing formin regulatory complex A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p. go-plus.json Bud14-Kel1-Kel2 complex|KFRC complex http://purl.obolibrary.org/obo/GO_1990615 GO:1990616 biolink:BiologicalProcess magnesium ion export from mitochondrion The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore. go-plus.json magnesium ion efflux from mitochondrion http://purl.obolibrary.org/obo/GO_1990616 GO:1990617 biolink:CellularComponent CHOP-ATF4 complex A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits. go-plus.json CHOP-CREB-2 complex|ATF4-CHOP heterodimer|CHOP/ATF4 complex|CHOP-ATF4 heterodimer|GADD153-ATF4 complex http://purl.obolibrary.org/obo/GO_1990617 GO:1990618 biolink:CellularComponent obsolete ANPR-A:ANP complex OBSOLETE. The ANPR-A:ANP complex is composed of the hormone AMP bound to the extracellular domain of ANPR-A domain. It is formed in the atrium in response to atrial distension (high blood volume) and leads to guanylate cyclase activity of the ANPR-A receptor, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. Therefore, ANPR-A:ANP complex plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. go-plus.json ANPR-A:ANP complex http://purl.obolibrary.org/obo/GO_1990618 CHEBI:76863 biolink:ChemicalSubstance EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76863 GO:1990611 biolink:BiologicalProcess regulation of cytoplasmic translational initiation in response to stress Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_1990611 GO:1990612 biolink:CellularComponent Sad1-Kms1 LINC complex A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair. go-plus.json http://purl.obolibrary.org/obo/GO_1990612 CHEBI:27817 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GlcNAc-(1->3)-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_27817 CHEBI:76864 biolink:ChemicalSubstance (2S,3S)-beta-methylphenylalanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76864 chebi_ph7_3 CHEBI:76861 biolink:ChemicalSubstance EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76861 GO:1990613 biolink:BiologicalProcess mitochondrial membrane fusion The joining of two lipid bilayers that surround the mitochondria. go-plus.json http://purl.obolibrary.org/obo/GO_1990613 CHEBI:27819 biolink:ChemicalSubstance clavaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27819 GO:1990614 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990614 CHEBI:27823 biolink:ChemicalSubstance (5-hydroxyindol-3-yl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27823 CHEBI:76878 biolink:ChemicalSubstance EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76878 CHEBI:76879 biolink:ChemicalSubstance EC 2.6.1.* (transaminase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76879 CHEBI:76876 biolink:ChemicalSubstance EC 2.2.1.* (transketolase/transaldolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76876 CHEBI:27825 biolink:ChemicalSubstance 3',5-dihydroxy-3,4',7-trimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27825 GO:1990620 biolink:CellularComponent ANPR-A receptor complex A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. go-plus.json NPR1 receptor complex http://purl.obolibrary.org/obo/GO_1990620 GO:1990621 biolink:CellularComponent ESCRT IV complex An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1. go-plus.json Vps4-Vta1 complex|VPS4A/B complex|vacuolar protein sorting-associated complex|Vps4 complex|Vta1-Vps4 complex|VPS4A-VPS4B|ESCRT-IV http://purl.obolibrary.org/obo/GO_1990621 CHEBI:27826 biolink:ChemicalSubstance (S)-4-hydroxymandelonitrile beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27826 chebi_ph7_3 CHEBI:27820 biolink:ChemicalSubstance prostaglandin A2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27820 CHEBI:27821 biolink:ChemicalSubstance (S)-methylmalonaldehydic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27821 CHEBI:27822 biolink:ChemicalSubstance 2-aminobenzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_27822 CHEBI:62230 biolink:ChemicalSubstance GDP-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62230 chebi_ph7_3 UBERON:0010272 biolink:AnatomicalEntity hyoid apparatus A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage go-plus.json apparatus hyoideus|hyolingual system|apparatus hyobranchialis|hyobranchial apparatus http://purl.obolibrary.org/obo/UBERON_0010272 UBERON:0010273 biolink:AnatomicalEntity zone of hyoid bone A zone of bone organ that is part of a hyoid bone. go-plus.json hyoid bone zone http://purl.obolibrary.org/obo/UBERON_0010273 CHEBI:62233 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62233 chebi_ph7_3 CHEBI:62234 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)-L-lysyl-D-alanyl-D-alanine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62234 chebi_ph7_3 UBERON:0010276 biolink:AnatomicalEntity space in vertebral column Any anatomical space that is part of a vertebral column. go-plus.json vertebral conduit|vertebral column opening http://purl.obolibrary.org/obo/UBERON_0010276 CHEBI:62231 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)3-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62231 CHEBI:62232 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62232 CHEBI:62237 biolink:ChemicalSubstance cardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62237 chebi_ph7_3 CHEBI:62235 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)3-L-lysyl-D-alanyl-D-alanine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62235 chebi_ph7_3 CHEBI:62236 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)5-L-lysyl-D-alanyl-D-alanine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62236 chebi_ph7_3 CHEBI:62239 biolink:ChemicalSubstance 3-hydroxydecanoyl-3-hydroxydecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62239 chebi_ph7_3 GO:1990626 biolink:BiologicalProcess mitochondrial outer membrane fusion The membrane organization process that joins two mitochondrial outer membranes to form a single membrane. go-plus.json mitochondrion outer membrane fusion http://purl.obolibrary.org/obo/GO_1990626 CHEBI:76870 biolink:ChemicalSubstance EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76870 CHEBI:76871 biolink:ChemicalSubstance EC 2.1.1.* (methyltransferases) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76871 GO:1990627 biolink:BiologicalProcess mitochondrial inner membrane fusion The membrane organization process that joins two mitochondrial inner membranes to form a single membrane. go-plus.json mitochondrion inner membrane fusion http://purl.obolibrary.org/obo/GO_1990627 GO:1990628 biolink:CellularComponent obsolete Sigma-E factor negative regulation complex OBSOLETE. A protein complex consisting of RseA, RseB and RpoE. It form the inactive form of the sigma-E transcription factor. In response to stress, outer membrane proteins accumulate in the periplasm and activate cleavage of RseA periplasmic domain by DegS, triggering a proteolytic cascade that frees sigma-E to activate gene expression. RseB binding to RseA prevents activated DegS from cleaving RseA. Sigma-E-mediated envelope stress response is the major pathway to ensure homeostasis in the envelope compartment of the cell. go-plus.json RseA-RseB-RpoE complex|Sigma-E factor negative regulation complex http://purl.obolibrary.org/obo/GO_1990628 NCBITaxon:109871 biolink:OrganismalEntity Batrachochytrium dendrobatidis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_109871 GO:1990629 biolink:CellularComponent phospholamban complex A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels. go-plus.json cardiac phospholamban complex|cardiac PLN complex|cardiac PLB complex http://purl.obolibrary.org/obo/GO_1990629 GO:1990622 biolink:CellularComponent CHOP-ATF3 complex A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits. go-plus.json GADD153-ATF3 complex|ATF3-CHOP complex|CHOP-ATF3 heterodimeric complex|CHOP-ATF3 heterodimer http://purl.obolibrary.org/obo/GO_1990622 CHEBI:27827 biolink:ChemicalSubstance paraoxon go-plus.json http://purl.obolibrary.org/obo/CHEBI_27827 chebi_ph7_3 CHEBI:76874 biolink:ChemicalSubstance EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76874 GO:1990623 biolink:CellularComponent Herring body The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively. go-plus.json neurosecretory body http://purl.obolibrary.org/obo/GO_1990623 GO:1990624 biolink:MolecularActivity guanyl nucleotide exchange factor inhibitor activity Binds to and stops, prevents or reduces the activity of a guanyl nucleotide exchange factor. go-plus.json http://purl.obolibrary.org/obo/GO_1990624 CHEBI:76872 biolink:ChemicalSubstance 2-iminobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76872 GO:1990625 biolink:BiologicalProcess negative regulation of cytoplasmic translational initiation in response to stress Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress. go-plus.json http://purl.obolibrary.org/obo/GO_1990625 GO:0050268 biolink:MolecularActivity coniferyl-alcohol dehydrogenase activity Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH. RHEA:22444|MetaCyc:RXN-2602|EC:1.1.1.194 go-plus.json coniferyl-alcohol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050268 GO:0050269 biolink:MolecularActivity coniferyl-aldehyde dehydrogenase activity Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+. MetaCyc:RXN-1241|EC:1.2.1.68 go-plus.json coniferyl aldehyde:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050269 GO:0050266 biolink:MolecularActivity rosmarinate synthase activity Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate. RHEA:22344|EC:2.3.1.140|MetaCyc:ROSMARINATE-SYNTHASE-RXN go-plus.json caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity|rosmarinic acid synthase activity|caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity|4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity http://purl.obolibrary.org/obo/GO_0050266 GO:0050267 biolink:MolecularActivity rubber cis-polyprenylcistransferase activity Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit. EC:2.5.1.20|RHEA:18801|MetaCyc:2.5.1.20-RXN go-plus.json rubber allyltransferase activity|cis-prenyl transferase activity|rubber polymerase activity|rubber prenyltransferase activity|rubber transferase activity|isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity|poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity http://purl.obolibrary.org/obo/GO_0050267 GO:0015939 biolink:BiologicalProcess pantothenate metabolic process The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. go-plus.json pantothenate metabolism|vitamin B5 metabolism|vitamin B5 metabolic process http://purl.obolibrary.org/obo/GO_0015939 GO:1902018 biolink:BiologicalProcess negative regulation of cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. go-plus.json down-regulation of cilium biogenesis|negative regulation of cilium biogenesis|down-regulation of ciliogenesis|down regulation of cilium assembly|negative regulation of ciliogenesis|downregulation of cilium assembly|inhibition of cilium biogenesis|downregulation of ciliogenesis|down regulation of cilium biogenesis|down-regulation of cilium assembly|down regulation of ciliogenesis|downregulation of cilium biogenesis|inhibition of ciliogenesis|inhibition of cilium assembly http://purl.obolibrary.org/obo/GO_1902018 GO:1902019 biolink:BiologicalProcess regulation of cilium-dependent cell motility Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. go-plus.json regulation of cilium cell motility|regulation of ciliary cell motility http://purl.obolibrary.org/obo/GO_1902019 GO:1902016 biolink:BiologicalProcess poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid. go-plus.json poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid anabolism|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid synthesis|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid formation|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis http://purl.obolibrary.org/obo/GO_1902016 GO:1902017 biolink:BiologicalProcess regulation of cilium assembly Any process that modulates the frequency, rate or extent of cilium assembly. go-plus.json regulation of ciliogenesis|regulation of cilium biogenesis http://purl.obolibrary.org/obo/GO_1902017 GO:1902014 biolink:BiologicalProcess poly(glycerol phosphate) teichoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid. go-plus.json poly(glycerol phosphate) teichoic acid anabolism|poly(glycerol phosphate) teichoic acid synthesis|poly(glycerol phosphate) teichoic acid formation|poly(glycerol phosphate) teichoic acid biosynthesis http://purl.obolibrary.org/obo/GO_1902014 GO:0015935 biolink:CellularComponent small ribosomal subunit The smaller of the two subunits of a ribosome. go-plus.json ribosomal small subunit http://purl.obolibrary.org/obo/GO_0015935 goslim_pir GO:0015936 biolink:BiologicalProcess coenzyme A metabolic process The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. go-plus.json coenzyme A metabolism|CoA metabolism http://purl.obolibrary.org/obo/GO_0015936 GO:1902015 biolink:BiologicalProcess poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid. go-plus.json poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism http://purl.obolibrary.org/obo/GO_1902015 GO:0015937 biolink:BiologicalProcess coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. MetaCyc:PWY-4221|MetaCyc:COA-PWY|MetaCyc:PANTOSYN-PWY go-plus.json coenzyme A anabolism|coenzyme A synthesis|coenzyme A biosynthesis|coenzyme A formation|CoA biosynthesis http://purl.obolibrary.org/obo/GO_0015937 GO:1902012 biolink:BiologicalProcess poly(ribitol phosphate) teichoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid. go-plus.json poly(ribitol phosphate) teichoic acid anabolism|poly(ribitol phosphate) teichoic acid synthesis|poly(ribitol phosphate) teichoic acid formation|poly(ribitol phosphate) teichoic acid biosynthesis http://purl.obolibrary.org/obo/GO_1902012 GO:0015938 biolink:BiologicalProcess coenzyme A catabolic process The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. go-plus.json coenzyme A breakdown|coenzyme A catabolism|CoA catabolism|coenzyme A degradation http://purl.obolibrary.org/obo/GO_0015938 GO:1902013 biolink:BiologicalProcess poly(glycerol phosphate) teichoic acid metabolic process The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid. go-plus.json poly(glycerol phosphate) teichoic acid metabolism http://purl.obolibrary.org/obo/GO_1902013 GO:1902021 biolink:BiologicalProcess regulation of bacterial-type flagellum-dependent cell motility Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility. go-plus.json regulation of bacterial-type flagellar cell motility|regulation of bacterial-type flagellum cell motility|regulation of flagellin-based flagellar cell motility http://purl.obolibrary.org/obo/GO_1902021 GO:0015931 biolink:BiologicalProcess nucleobase-containing compound transport The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json nucleobase, nucleoside, nucleotide and nucleic acid transport http://purl.obolibrary.org/obo/GO_0015931 goslim_pir|goslim_yeast GO:0015932 biolink:MolecularActivity nucleobase-containing compound transmembrane transporter activity Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other. go-plus.json nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015932 GO:1902022 biolink:BiologicalProcess L-lysine transport The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1902022 GO:0015933 biolink:MolecularActivity obsolete flavin-containing electron transporter OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins. go-plus.json flavin-containing electron transporter http://purl.obolibrary.org/obo/GO_0015933 GO:1902020 biolink:BiologicalProcess negative regulation of cilium-dependent cell motility Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. go-plus.json down regulation of ciliary cell motility|negative regulation of ciliary cell motility|downregulation of ciliary cell motility|negative regulation of cilium cell motility|down-regulation of ciliary cell motility|inhibition of ciliary cell motility http://purl.obolibrary.org/obo/GO_1902020 GO:0015934 biolink:CellularComponent large ribosomal subunit The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). go-plus.json ribosomal large subunit http://purl.obolibrary.org/obo/GO_0015934 GO:0015930 biolink:MolecularActivity glutamate synthase activity Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors. go-plus.json http://purl.obolibrary.org/obo/GO_0015930 GO:0050260 biolink:MolecularActivity ribose-5-phosphate-ammonia ligase activity Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate. KEGG_REACTION:R01053|MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN|EC:6.3.4.7|RHEA:13777 go-plus.json ribose 5-phosphate aminotransferase activity|5-phosphoribosylamine synthetase activity|ammonia-ribose 5-phosphate aminotransferase activity|ribose-5-phosphate:ammonia ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0050260 CHEBI:37273 biolink:ChemicalSubstance cis-11-tetradecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37273 GO:0050261 biolink:MolecularActivity ribose isomerase activity Catalysis of the reaction: ribofuranose = D-ribulose. KEGG_REACTION:R01081|MetaCyc:RIBOSE-ISOMERASE-RXN|RHEA:20796|EC:5.3.1.20 go-plus.json D-ribose ketol-isomerase activity|D-ribose aldose-ketose-isomerase activity|D-ribose isomerase activity http://purl.obolibrary.org/obo/GO_0050261 CHEBI:37274 biolink:ChemicalSubstance trans-11-tetradecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37274 CHEBI:37271 biolink:ChemicalSubstance trans-2-tetradecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37271 GO:0050264 biolink:MolecularActivity rifamycin-B oxidase activity Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O. MetaCyc:RIFAMYCIN-B-OXIDASE-RXN|EC:1.10.3.6|RHEA:11292|KEGG_REACTION:R03736 go-plus.json rifamycin-B:oxygen oxidoreductase activity|rifamycin B oxidase activity|rifamycin-B-oxidase activity http://purl.obolibrary.org/obo/GO_0050264 GO:0050265 biolink:MolecularActivity RNA uridylyltransferase activity Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1). MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN|RHEA:14785|EC:2.7.7.52|Reactome:R-HSA-8941312 go-plus.json polynucleotide uridylyltransferase activity|UTP:RNA uridylyltransferase activity|TUT activity|poly(U) polymerase activity|terminal uridylyltransferase activity http://purl.obolibrary.org/obo/GO_0050265 GO:0050262 biolink:MolecularActivity ribosylnicotinamide kinase activity Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide. Reactome:R-HSA-8869627|Reactome:R-HSA-8869633|MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN|KEGG_REACTION:R02324|EC:2.7.1.22|RHEA:14017 go-plus.json nicotinamide riboside kinase activity|ribosylnicotinamide kinase (phosphorylating)|ATP:N-ribosylnicotinamide 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050262 GO:0050263 biolink:MolecularActivity ribosylpyrimidine nucleosidase activity Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine. EC:3.2.2.8|MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN|RHEA:56816 go-plus.json nucleoside ribohydrolase activity|N-ribosylpyrimidine ribohydrolase activity|pyrimidine-nucleoside ribohydrolase activity|RihB|YeiK|N-ribosylpyrimidine nucleosidase activity|pyrimidine nucleosidase activity http://purl.obolibrary.org/obo/GO_0050263 CHEBI:37276 biolink:ChemicalSubstance (1-hydroxycyclohexyl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37276 GO:0001301 biolink:BiologicalProcess progressive alteration of chromatin involved in cell aging Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype. go-plus.json progressive alteration of chromatin during cell aging|progressive alteration of chromatin during cell ageing|age-dependent accumulation of genetic damage http://purl.obolibrary.org/obo/GO_0001301 GO:0050279 biolink:MolecularActivity sepiapterin deaminase activity Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3. EC:3.5.4.24|MetaCyc:SEPIAPTERIN-DEAMINASE-RXN|RHEA:14025 go-plus.json sepiapterin aminohydrolase activity http://purl.obolibrary.org/obo/GO_0050279 GO:0001302 biolink:BiologicalProcess obsolete replicative cell aging OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division. go-plus.json replicative cell ageing http://purl.obolibrary.org/obo/GO_0001302 GO:0050277 biolink:MolecularActivity sedoheptulokinase activity Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate. KEGG_REACTION:R01844|RHEA:23844|EC:2.7.1.14|MetaCyc:SEDOHEPTULOKINASE-RXN|Reactome:R-HSA-8959719 go-plus.json ATP:sedoheptulose 7-phosphotransferase activity|heptulokinase activity|sedoheptulokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0050277 GO:0001303 biolink:BiologicalProcess obsolete nucleolar fragmentation involved in replicative aging OBSOLETE. A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells. go-plus.json nucleolar fragmentation during replicative ageing|nucleolar fragmentation during replicative aging http://purl.obolibrary.org/obo/GO_0001303 GO:0050278 biolink:MolecularActivity sedoheptulose-bisphosphatase activity Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate. EC:3.1.3.37|MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN|RHEA:17461 go-plus.json SBPase activity|sedoheptulose-1,7-bisphosphatase activity|sedoheptulose diphosphatase activity|sedoheptulose bisphosphatase activity|sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity|sedoheptulose 1,7-diphosphate phosphatase activity|sedoheptulose 1,7-diphosphatase activity|sedoheptulose 1,7-bisphosphatase activity http://purl.obolibrary.org/obo/GO_0050278 GO:0001304 biolink:BiologicalProcess obsolete progressive alteration of chromatin involved in replicative cell aging OBSOLETE. A process that results in changes in chromatin structure contributing to replicative cell aging. go-plus.json progressive alteration of chromatin during replicative cell ageing|progressive alteration of chromatin during replicative cell aging http://purl.obolibrary.org/obo/GO_0001304 CHEBI:37291 biolink:ChemicalSubstance (3S)-3-isopropenyl-6-oxoheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37291 CHEBI:37292 biolink:ChemicalSubstance 1-(phosphoribosyl)imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_37292 GO:0001300 biolink:BiologicalProcess obsolete chronological cell aging OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state. go-plus.json chronological cell ageing http://purl.obolibrary.org/obo/GO_0001300 CHEBI:37290 biolink:ChemicalSubstance 1-(phosphoribosyl)imidazolecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37290 GO:1902029 biolink:BiologicalProcess positive regulation of histone H3-K18 acetylation Any process that activates or increases the frequency, rate or extent of histone H3-K18 acetylation. go-plus.json positive regulation of histone H3 acetylation at K18|upregulation of histone H3K18 acetylation|activation of histone H3 acetylation at K18|upregulation of histone H3-K18 acetylation|up-regulation of histone H3 acetylation at K18|up regulation of histone H3K18 acetylation|positive regulation of histone H3K18 acetylation|up-regulation of histone H3-K18 acetylation|activation of histone H3-K18 acetylation|upregulation of histone H3 acetylation at K18|activation of histone H3K18 acetylation|up-regulation of histone H3K18 acetylation|up regulation of histone H3 acetylation at K18|up regulation of histone H3-K18 acetylation http://purl.obolibrary.org/obo/GO_1902029 GO:1902027 biolink:BiologicalProcess positive regulation of cartilage condensation Any process that activates or increases the frequency, rate or extent of cartilage condensation. go-plus.json up regulation of cartilage condensation|upregulation of cartilage condensation|up-regulation of cartilage condensation|activation of cartilage condensation http://purl.obolibrary.org/obo/GO_1902027 GO:1902028 biolink:BiologicalProcess regulation of histone H3-K18 acetylation Any process that modulates the frequency, rate or extent of histone H3-K18 acetylation. go-plus.json regulation of histone H3K18 acetylation|regulation of histone H3 acetylation at K18 http://purl.obolibrary.org/obo/GO_1902028 GO:1902025 biolink:BiologicalProcess nitrate import The directed movement of nitrate into a cell or organelle. go-plus.json nitrate influx|nitrate uptake http://purl.obolibrary.org/obo/GO_1902025 GO:0015946 biolink:BiologicalProcess methanol oxidation The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M. MetaCyc:CO2FORM-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0015946 GO:0015947 biolink:BiologicalProcess methane metabolic process The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. go-plus.json methane metabolism http://purl.obolibrary.org/obo/GO_0015947 GO:1902026 biolink:BiologicalProcess regulation of cartilage condensation Any process that modulates the frequency, rate or extent of cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/GO_1902026 GO:1902023 biolink:BiologicalProcess L-arginine transport The directed movement of a L-arginine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-arginine uptake|L-arginine import http://purl.obolibrary.org/obo/GO_1902023 GO:0015948 biolink:BiologicalProcess methanogenesis The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. Wikipedia:Methanogenesis|UM-BBD_pathwayID:meth go-plus.json methane biosynthesis|methane biosynthetic process http://purl.obolibrary.org/obo/GO_0015948 goslim_pir|goslim_metagenomics GO:0015949 biolink:BiologicalProcess nucleobase-containing small molecule interconversion The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule. MetaCyc:P1-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0015949 goslim_pir GO:1902024 biolink:BiologicalProcess L-histidine transport The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1902024 GO:1902032 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in response to osmotic stress. go-plus.json regulation of gene-specific transcription from RNA polymerase II promoter involved in response to osmotic stress|regulation of transcription from Pol II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress|global transcription regulation from Pol II promoter involved in response to osmotic stress|regulation of transcription from RNA polymerase II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter, global involved in osmotic response|regulation of global transcription from Pol II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter, global involved in response to osmotic stress|regulation of transcription from Pol II promoter involved in osmotic response|regulation of global transcription from Pol II promoter involved in osmotic stress response|regulation of global transcription from Pol II promoter involved in response to osmotic stress|regulation of transcription from RNA polymerase II promoter, global involved in osmotic stress response|regulation of transcription from Pol II promoter involved in response to osmotic stress|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic response|global transcription regulation from Pol II promoter involved in osmotic response|global transcription regulation from Pol II promoter involved in osmotic stress response|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic stress response http://purl.obolibrary.org/obo/GO_1902032 GO:0015942 biolink:BiologicalProcess formate metabolic process The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. go-plus.json formate metabolism http://purl.obolibrary.org/obo/GO_0015942 GO:0015943 biolink:BiologicalProcess formate biosynthetic process The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. go-plus.json formic acid biosynthetic process|formic acid biosynthesis|formate anabolism|formate synthesis|formate formation|formate biosynthesis http://purl.obolibrary.org/obo/GO_0015943 GO:1902033 biolink:BiologicalProcess regulation of hematopoietic stem cell proliferation Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation. go-plus.json regulation of hemopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 GO:0015944 biolink:BiologicalProcess formate oxidation The chemical reactions and pathways by which formate is converted to CO2. MetaCyc:PWY-1881 go-plus.json formic acid oxidation http://purl.obolibrary.org/obo/GO_0015944 GO:1902030 biolink:BiologicalProcess negative regulation of histone H3-K18 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K18 acetylation. go-plus.json down regulation of histone H3 acetylation at K18|down-regulation of histone H3-K18 acetylation|downregulation of histone H3 acetylation at K18|inhibition of histone H3K18 acetylation|downregulation of histone H3-K18 acetylation|negative regulation of histone H3 acetylation at K18|down-regulation of histone H3 acetylation at K18|down regulation of histone H3-K18 acetylation|inhibition of histone H3-K18 acetylation|down regulation of histone H3K18 acetylation|downregulation of histone H3K18 acetylation|inhibition of histone H3 acetylation at K18|negative regulation of histone H3K18 acetylation|down-regulation of histone H3K18 acetylation http://purl.obolibrary.org/obo/GO_1902030 GO:1902031 biolink:BiologicalProcess regulation of NADP metabolic process Any process that modulates the frequency, rate or extent of NADP metabolic process. go-plus.json regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolic process|regulation of oxidized NADP metabolic process|regulation of NADPH metabolic process|regulation of reduced NADP metabolic process|regulation of NADP metabolism|regulation of reduced NADP metabolism|regulation of NADPH metabolism|regulation of oxidized NADP metabolism|regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolism|regulation of NADP (oxidized) metabolism|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolism|regulation of nicotinamide adenine dinucleotide phosphate metabolism|regulation of NADP (reduced) metabolic process|regulation of NAD phosphorylation and dephosphorylation|regulation of NADP (reduced) metabolism|regulation of nicotinamide adenine dinucleotide phosphate metabolic process|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolic process|regulation of NADP (oxidized) metabolic process http://purl.obolibrary.org/obo/GO_1902031 GO:0015945 biolink:BiologicalProcess methanol metabolic process The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent. go-plus.json methanol metabolism http://purl.obolibrary.org/obo/GO_0015945 GO:0015940 biolink:BiologicalProcess pantothenate biosynthetic process The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. MetaCyc:PWY-3961|MetaCyc:PANTO-PWY|MetaCyc:PWY-4221|MetaCyc:PANTOSYN-PWY go-plus.json pantothenate anabolism|pantothenate synthesis|pantothenate biosynthesis|pantothenate anabolism from valine|pantothenate formation|vitamin B5 biosynthesis|pantothenate synthesis from valine|vitamin B5 biosynthetic process|pantothenate biosynthesis from valine|pantothenate biosynthetic process from valine|pantothenate formation from valine|pantothenate anabolism from 2-oxypantoyl lactone|pantothenate synthesis from 2-oxypantoyl lactone|pantothenate biosynthesis from 2-oxypantoyl lactone|pantothenate biosynthetic process from 2-oxypantoyl lactone|pantothenate formation from 2-oxypantoyl lactone|pantothenate biosynthetic process from 2-dehydropantolactone http://purl.obolibrary.org/obo/GO_0015940 GO:0015941 biolink:BiologicalProcess pantothenate catabolic process The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. go-plus.json pantothenate catabolism|vitamin B5 catabolism|pantothenate degradation|pantothenate breakdown|vitamin B5 catabolic process http://purl.obolibrary.org/obo/GO_0015941 GO:0001309 biolink:BiologicalProcess obsolete age-dependent telomere shortening OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process. go-plus.json age-dependent telomere shortening http://purl.obolibrary.org/obo/GO_0001309 GO:0050271 biolink:MolecularActivity S-alkylcysteine lyase activity Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate. RHEA:22424|MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN|EC:4.4.1.6 go-plus.json S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity|alkyl cysteine lyase activity|S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)|alkylcysteine lyase activity|S-alkyl-L-cysteine lyase activity|S-alkyl-L-cysteine sulfoxide lyase activity|S-alkyl-L-cysteinase activity|S-alkylcysteinase activity http://purl.obolibrary.org/obo/GO_0050271 GO:0050272 biolink:MolecularActivity S-carboxymethylcysteine synthase activity Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+). RHEA:22868|EC:4.5.1.5|KEGG_REACTION:R04003|MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN go-plus.json 3-chloro-L-alanine chloride-lyase (adding thioglycolate)|S-carboxymethyl-L-cysteine synthase activity|3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming) http://purl.obolibrary.org/obo/GO_0050272 GO:0050270 biolink:MolecularActivity S-adenosylhomocysteine deaminase activity Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+). RHEA:20716|EC:3.5.4.28|KEGG_REACTION:R00193|MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN go-plus.json adenosylhomocysteine deaminase activity|S-adenosyl-L-homocysteine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0050270 CHEBI:37283 biolink:ChemicalSubstance heptanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_37283 GO:0050275 biolink:MolecularActivity scopoletin glucosyltransferase activity Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP. RHEA:20453|EC:2.4.1.128|KEGG_REACTION:R03594|MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN go-plus.json UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-scopoletin glucosyltransferase activity|UDPglucose:scopoletin O-beta-D-glucosyltransferase activity|UDPglucose:scopoletin glucosyltransferase activity|SGTase activity http://purl.obolibrary.org/obo/GO_0050275 GO:0001305 biolink:BiologicalProcess obsolete progressive alteration of chromatin involved in chronological cell aging OBSOLETE. A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells. go-plus.json progressive alteration of chromatin during chronological cell aging|progressive alteration of chromatin during chronological cell ageing http://purl.obolibrary.org/obo/GO_0001305 GO:0050276 biolink:MolecularActivity scyllo-inosamine 4-kinase activity Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+). MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN|RHEA:18605|EC:2.7.1.65|KEGG_REACTION:R03384 go-plus.json ATP:inosamine phosphotransferase activity|scyllo-inosamine kinase activity|scyllo-inosamine kinase (phosphorylating)|ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050276 GO:0001306 biolink:BiologicalProcess age-dependent response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0001306 GO:0050273 biolink:MolecularActivity S-succinylglutathione hydrolase activity Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate. EC:3.1.2.13|KEGG_REACTION:R00499|MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN|RHEA:16713 go-plus.json http://purl.obolibrary.org/obo/GO_0050273 GO:0001307 biolink:BiologicalProcess obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication. go-plus.json extrachromosomal circular DNA accumulation during replicative cell ageing|extrachromosomal circular DNA accumulation during replicative cell aging http://purl.obolibrary.org/obo/GO_0001307 GO:0050274 biolink:MolecularActivity salicyl-alcohol beta-D-glucosyltransferase activity Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP. KEGG_REACTION:R03558|RHEA:11512|MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.172 go-plus.json salicyl-alcohol b-D-glucosyltransferase activity|UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity|UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity|salicyl-alcohol glucosyltransferase activity|uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity|UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050274 GO:0001308 biolink:BiologicalProcess obsolete negative regulation of chromatin silencing involved in replicative cell aging OBSOLETE. The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins. go-plus.json loss of chromatin silencing during replicative cell ageing|loss of chromatin silencing involved in replicative cell aging http://purl.obolibrary.org/obo/GO_0001308 CHEBI:37287 biolink:ChemicalSubstance (3R)-3-isopropenyl-6-oxoheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37287 GO:0050288 biolink:MolecularActivity sorbose dehydrogenase activity Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2). MetaCyc:SORBOSE-DEHYDROGENASE-RXN|EC:1.1.99.12|RHEA:14713|KEGG_REACTION:R01696 go-plus.json L-sorbose:acceptor 5-oxidoreductase activity|L-sorbose:(acceptor) 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050288 GO:0050289 biolink:MolecularActivity spermidine dehydrogenase activity Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor. RHEA:14273|EC:1.5.99.6|MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN go-plus.json spermidine:(acceptor) oxidoreductase activity|spermidine:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050289 CHEBI:52897 biolink:ChemicalSubstance sphingosylphosphocholine acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52897 GO:0015917 biolink:BiologicalProcess aminophospholipid transport The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group. go-plus.json http://purl.obolibrary.org/obo/GO_0015917 GO:0015918 biolink:BiologicalProcess sterol transport The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0015918 GO:1902038 biolink:BiologicalProcess positive regulation of hematopoietic stem cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. go-plus.json up-regulation of hematopoietic stem cell differentiation|positive regulation of haemopoietic stem cell differentiation|activation of haematopoietic stem cell differentiation|up-regulation of haematopoietic stem cell differentiation|up regulation of haemopoietic stem cell differentiation|up regulation of hemopoietic stem cell differentiation|activation of hemopoietic stem cell differentiation|positive regulation of hemopoietic stem cell differentiation|upregulation of hematopoietic stem cell differentiation|upregulation of haemopoietic stem cell differentiation|positive regulation of haematopoietic stem cell differentiation|up regulation of haematopoietic stem cell differentiation|up regulation of hematopoietic stem cell differentiation|up-regulation of hemopoietic stem cell differentiation|activation of hematopoietic stem cell differentiation|up-regulation of haemopoietic stem cell differentiation|activation of haemopoietic stem cell differentiation|upregulation of hemopoietic stem cell differentiation|upregulation of haematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902038 GO:0015919 biolink:BiologicalProcess peroxisomal membrane transport The directed movement of substances to, from or across the peroxisomal membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0015919 GO:1902039 biolink:BiologicalProcess negative regulation of seed dormancy process Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process. go-plus.json downregulation of seed dormancy|down regulation of seed dormancy process|down-regulation of seed dormancy|negative regulation of seed dormancy|downregulation of seed dormancy process|inhibition of seed dormancy|down-regulation of seed dormancy process|inhibition of seed dormancy process|down regulation of seed dormancy http://purl.obolibrary.org/obo/GO_1902039 GO:1902036 biolink:BiologicalProcess regulation of hematopoietic stem cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. go-plus.json regulation of hemopoietic stem cell differentiation|regulation of haemopoietic stem cell differentiation|regulation of haematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 GO:0015913 biolink:BiologicalProcess short-chain fatty acid import The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6. go-plus.json short-chain fatty acid uptake http://purl.obolibrary.org/obo/GO_0015913 GO:1902037 biolink:BiologicalProcess negative regulation of hematopoietic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. go-plus.json inhibition of hematopoietic stem cell differentiation|downregulation of hemopoietic stem cell differentiation|downregulation of haemopoietic stem cell differentiation|down regulation of hematopoietic stem cell differentiation|down-regulation of hemopoietic stem cell differentiation|down regulation of haemopoietic stem cell differentiation|negative regulation of hemopoietic stem cell differentiation|down-regulation of haematopoietic stem cell differentiation|negative regulation of haematopoietic stem cell differentiation|inhibition of haemopoietic stem cell differentiation|downregulation of hematopoietic stem cell differentiation|inhibition of hemopoietic stem cell differentiation|downregulation of haematopoietic stem cell differentiation|down regulation of haematopoietic stem cell differentiation|down-regulation of hematopoietic stem cell differentiation|inhibition of haematopoietic stem cell differentiation|down regulation of hemopoietic stem cell differentiation|down-regulation of haemopoietic stem cell differentiation|negative regulation of haemopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902037 GO:0015914 biolink:BiologicalProcess phospholipid transport The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. go-plus.json http://purl.obolibrary.org/obo/GO_0015914 GO:1902034 biolink:BiologicalProcess negative regulation of hematopoietic stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation. go-plus.json down-regulation of hemopoietic stem cell proliferation|down regulation of hematopoietic stem cell proliferation|negative regulation of hemopoietic stem cell proliferation|downregulation of hematopoietic stem cell proliferation|inhibition of hemopoietic stem cell proliferation|down-regulation of hematopoietic stem cell proliferation|down regulation of hemopoietic stem cell proliferation|inhibition of hematopoietic stem cell proliferation|downregulation of hemopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902034 GO:0015915 biolink:BiologicalProcess fatty-acyl group transport The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid. go-plus.json fatty acyl transport http://purl.obolibrary.org/obo/GO_0015915 GO:0015916 biolink:BiologicalProcess fatty-acyl-CoA transport The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A). go-plus.json fatty acyl-CoA transport|fatty acyl coenzyme A transport|fatty acyl CoA transport http://purl.obolibrary.org/obo/GO_0015916 GO:1902035 biolink:BiologicalProcess positive regulation of hematopoietic stem cell proliferation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation. go-plus.json activation of hemopoietic stem cell proliferation|positive regulation of hemopoietic stem cell proliferation|upregulation of hematopoietic stem cell proliferation|up regulation of hematopoietic stem cell proliferation|up-regulation of hemopoietic stem cell proliferation|activation of hematopoietic stem cell proliferation|upregulation of hemopoietic stem cell proliferation|up-regulation of hematopoietic stem cell proliferation|up regulation of hemopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902035 GO:1902043 biolink:BiologicalProcess positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. go-plus.json activation of death receptor-mediated apoptosis|upregulation of extrinsic apoptotic signaling pathway via death domain receptors|up-regulation of death receptor-mediated apoptosis|up-regulation of extrinsic apoptotic signaling pathway via death domain receptors|activation of extrinsic apoptotic signaling pathway via death domain receptors|upregulation of death receptor-mediated apoptosis|up regulation of extrinsic apoptotic signaling pathway via death domain receptors|up regulation of death receptor-mediated apoptosis|positive regulation of death receptor-mediated apoptosis http://purl.obolibrary.org/obo/GO_1902043 CHEBI:37259 biolink:ChemicalSubstance 3-oxopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37259 GO:0015910 biolink:BiologicalProcess long-chain fatty acid import into peroxisome The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json peroxisomal long-chain fatty acid uptake|peroxisomal long-chain fatty acid import http://purl.obolibrary.org/obo/GO_0015910 GO:1902044 biolink:BiologicalProcess regulation of Fas signaling pathway Any process that modulates the frequency, rate or extent of Fas signaling pathway. go-plus.json regulation of FasL signaling pathway|regulation of Fas-FasL signaling pathway|regulation of FAS ligand-Fas signaling pathway|regulation of Fas receptor signaling pathway|regulation of Apo-1 signaling pathway|regulation of CD95 signaling pathway|regulation of FasR signaling pathway http://purl.obolibrary.org/obo/GO_1902044 GO:0015911 biolink:BiologicalProcess long-chain fatty acid import across plasma membrane The directed movement of long-chain fatty acids from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json plasma membrane long-chain fatty acid transport http://purl.obolibrary.org/obo/GO_0015911 CHEBI:37257 biolink:ChemicalSubstance phytanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37257 chebi_ph7_3 GO:1902041 biolink:BiologicalProcess regulation of extrinsic apoptotic signaling pathway via death domain receptors Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. go-plus.json regulation of death receptor-mediated apoptosis http://purl.obolibrary.org/obo/GO_1902041 GO:1902042 biolink:BiologicalProcess negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. go-plus.json down regulation of extrinsic apoptotic signaling pathway via death domain receptors|inhibition of extrinsic apoptotic signaling pathway via death domain receptors|inhibition of death receptor-mediated apoptosis|down regulation of death receptor-mediated apoptosis|down-regulation of extrinsic apoptotic signaling pathway via death domain receptors|downregulation of death receptor-mediated apoptosis|downregulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of death receptor-mediated apoptosis|down-regulation of death receptor-mediated apoptosis http://purl.obolibrary.org/obo/GO_1902042 GO:0015912 biolink:BiologicalProcess short-chain fatty acid transport The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6. go-plus.json http://purl.obolibrary.org/obo/GO_0015912 CHEBI:37258 biolink:ChemicalSubstance 2-hydroxyphytanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37258 GO:1902040 biolink:BiologicalProcess positive regulation of seed dormancy process Any process that activates or increases the frequency, rate or extent of seed dormancy process. go-plus.json upregulation of seed dormancy|up-regulation of seed dormancy process|up regulation of seed dormancy|upregulation of seed dormancy process|positive regulation of seed dormancy|activation of seed dormancy|up regulation of seed dormancy process|up-regulation of seed dormancy|activation of seed dormancy process http://purl.obolibrary.org/obo/GO_1902040 CHEBI:37251 biolink:ChemicalSubstance 3-oxopalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37251 GO:0050282 biolink:MolecularActivity serine 2-dehydrogenase activity Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH. MetaCyc:SERINE-DEHYDROGENASE-RXN|RHEA:20884|EC:1.4.1.7 go-plus.json L-serine:NAD oxidoreductase (deaminating) activity|serine dehydrogenase activity|L-serine:NAD+ 2-oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0050282 GO:0050283 biolink:MolecularActivity serine-sulfate ammonia-lyase activity Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate. MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN|RHEA:15605|EC:4.3.1.10 go-plus.json (L-SOS)lyase activity|serine-sulphate ammonia-lyase activity|L-serine-O-sulfate ammonia-lyase (pyruvate-forming) http://purl.obolibrary.org/obo/GO_0050283 CHEBI:37252 biolink:ChemicalSubstance (E)-hexadec-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37252 GO:0050280 biolink:MolecularActivity sequoyitol dehydrogenase activity Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH. EC:1.1.1.143|MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN|RHEA:11300|KEGG_REACTION:R03497 go-plus.json 5-O-methyl-myo-inositol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050280 GO:0050281 biolink:MolecularActivity serine-glyoxylate transaminase activity Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine. RHEA:19125|MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN|EC:2.6.1.45 go-plus.json L-serine:glyoxylate aminotransferase activity|serine--glyoxylate aminotransferase activity|SGAT activity http://purl.obolibrary.org/obo/GO_0050281 CHEBI:37250 biolink:ChemicalSubstance (S)-3-hydroxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37250 GO:0050286 biolink:MolecularActivity sorbitol-6-phosphatase activity Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate. RHEA:24580|KEGG_REACTION:R02866|EC:3.1.3.50|MetaCyc:SORBITOL-6-PHOSPHATASE-RXN go-plus.json sorbitol-6-phosphate phosphohydrolase activity|sorbitol-6-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0050286 GO:0050287 biolink:MolecularActivity sorbose 5-dehydrogenase (NADP+) activity Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH. RHEA:15001|EC:1.1.1.123|KEGG_REACTION:R01694|MetaCyc:SORBOSE-5-DEHYDROGENASE-NADP+-RXN go-plus.json sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|L-sorbose:NADP+ 5-oxidoreductase activity|5-keto-D-fructose reductase activity|5-ketofructose reductase activity|reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity http://purl.obolibrary.org/obo/GO_0050287 GO:0050284 biolink:MolecularActivity sinapate 1-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose. EC:2.4.1.120|RHEA:13305|MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN go-plus.json UDP-glucose:sinapate D-glucosyltransferase activity|uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity|uridine diphosphoglucose-sinapate glucosyltransferase activity|UDPglucose:sinapic acid glucosyltransferase activity|UDPglucose:sinapate D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050284 CHEBI:37253 biolink:ChemicalSubstance elemental zinc go-plus.json http://purl.obolibrary.org/obo/CHEBI_37253 GO:0050285 biolink:MolecularActivity sinapine esterase activity Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate. KEGG_REACTION:R02381|MetaCyc:SINAPINE-ESTERASE-RXN|EC:3.1.1.49|RHEA:10016 go-plus.json aromatic choline esterase activity|sinapoylcholine sinapohydrolase activity http://purl.obolibrary.org/obo/GO_0050285 GO:0050299 biolink:MolecularActivity streptomycin 3''-kinase activity Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate. KEGG_REACTION:R02227|MetaCyc:STREPTOMYCIN-3-KINASE-RXN|EC:2.7.1.87|RHEA:18377 go-plus.json streptomycin 3''-phosphotransferase activity|ATP:streptomycin 3''-phosphotransferase activity|streptomycin 3''-kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0050299 CHEBI:37270 biolink:ChemicalSubstance 3-oxotetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37270 GO:0015928 biolink:MolecularActivity fucosidase activity Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0015928 GO:0015929 biolink:MolecularActivity hexosaminidase activity Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides. MetaCyc:3.2.1.52-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0015929 GO:1902049 biolink:BiologicalProcess neosartoricin catabolic process The chemical reactions and pathways resulting in the breakdown of neosartoricin. go-plus.json neosartoricin breakdown|neosartoricin catabolism|neosartoricin degradation http://purl.obolibrary.org/obo/GO_1902049 GO:1902047 biolink:BiologicalProcess polyamine transmembrane transport The process in which a polyamine macromolecule is transported across a membrane. go-plus.json polyamine import|polyamine uptake http://purl.obolibrary.org/obo/GO_1902047 GO:0015924 biolink:MolecularActivity mannosyl-oligosaccharide mannosidase activity Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides. EC:3.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0015924 GO:0015925 biolink:MolecularActivity galactosidase activity Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0015925 GO:1902048 biolink:BiologicalProcess neosartoricin metabolic process The chemical reactions and pathways involving neosartoricin. go-plus.json neosartoricin metabolism http://purl.obolibrary.org/obo/GO_1902048 GO:1902045 biolink:BiologicalProcess negative regulation of Fas signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway. go-plus.json inhibition of FasR signaling pathway|down regulation of Fas signaling pathway|negative regulation of Apo-1 signaling pathway|down-regulation of Apo-1 signaling pathway|downregulation of FasL signaling pathway|downregulation of Fas signaling pathway|downregulation of Fas-FasL signaling pathway|negative regulation of FAS ligand-Fas signaling pathway|down-regulation of FAS ligand-Fas signaling pathway|negative regulation of Fas receptor signaling pathway|down-regulation of Fas receptor signaling pathway|down regulation of FasL signaling pathway|inhibition of Apo-1 signaling pathway|down regulation of Fas-FasL signaling pathway|down-regulation of CD95 signaling pathway|negative regulation of CD95 signaling pathway|downregulation of FAS ligand-Fas signaling pathway|down-regulation of Fas signaling pathway|downregulation of Fas receptor signaling pathway|inhibition of FasL signaling pathway|down-regulation of FasR signaling pathway|inhibition of Fas-FasL signaling pathway|negative regulation of FasR signaling pathway|down regulation of FAS ligand-Fas signaling pathway|down regulation of Fas receptor signaling pathway|inhibition of Fas signaling pathway|down regulation of Apo-1 signaling pathway|inhibition of Fas receptor signaling pathway|downregulation of CD95 signaling pathway|inhibition of FAS ligand-Fas signaling pathway|downregulation of FasR signaling pathway|downregulation of Apo-1 signaling pathway|down regulation of CD95 signaling pathway|negative regulation of FasL signaling pathway|down-regulation of FasL signaling pathway|inhibition of CD95 signaling pathway|down-regulation of Fas-FasL signaling pathway|negative regulation of Fas-FasL signaling pathway|down regulation of FasR signaling pathway http://purl.obolibrary.org/obo/GO_1902045 GO:0015926 biolink:MolecularActivity glucosidase activity Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0015926 GO:1902046 biolink:BiologicalProcess positive regulation of Fas signaling pathway Any process that activates or increases the frequency, rate or extent of Fas signaling pathway. go-plus.json positive regulation of Apo-1 signaling pathway|upregulation of Fas signaling pathway|positive regulation of FasL signaling pathway|activation of Fas receptor signaling pathway|positive regulation of Fas-FasL signaling pathway|up-regulation of Fas receptor signaling pathway|upregulation of FasR signaling pathway|up regulation of FasL signaling pathway|up regulation of Fas-FasL signaling pathway|activation of FAS ligand-Fas signaling pathway|activation of CD95 signaling pathway|up-regulation of CD95 signaling pathway|positive regulation of FAS ligand-Fas signaling pathway|up regulation of Fas signaling pathway|activation of Fas signaling pathway|activation of FasR signaling pathway|up-regulation of Apo-1 signaling pathway|up-regulation of FasR signaling pathway|up regulation of FAS ligand-Fas signaling pathway|positive regulation of Fas receptor signaling pathway|upregulation of Fas-FasL signaling pathway|upregulation of FasL signaling pathway|up regulation of Fas receptor signaling pathway|positive regulation of CD95 signaling pathway|upregulation of Apo-1 signaling pathway|up regulation of CD95 signaling pathway|upregulation of FAS ligand-Fas signaling pathway|up-regulation of Fas-FasL signaling pathway|positive regulation of FasR signaling pathway|up-regulation of FasL signaling pathway|up-regulation of Fas signaling pathway|up regulation of FasR signaling pathway|upregulation of Fas receptor signaling pathway|activation of Fas-FasL signaling pathway|activation of FasL signaling pathway|up regulation of Apo-1 signaling pathway|upregulation of CD95 signaling pathway|up-regulation of FAS ligand-Fas signaling pathway|activation of Apo-1 signaling pathway http://purl.obolibrary.org/obo/GO_1902046 GO:0015927 biolink:MolecularActivity trehalase activity Catalysis of the hydrolysis of trehalose or a trehalose derivative. MetaCyc:TREHALA-RXN|RHEA:32675 go-plus.json http://purl.obolibrary.org/obo/GO_0015927 GO:1902054 biolink:BiologicalProcess negative regulation of neosartoricin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process. go-plus.json inhibition of neosartoricin anabolism|downregulation of neosartoricin biosynthesis|downregulation of neosartoricin biosynthetic process|inhibition of neosartoricin synthesis|down regulation of neosartoricin biosynthesis|down regulation of neosartoricin biosynthetic process|down regulation of neosartoricin anabolism|inhibition of neosartoricin biosynthetic process|inhibition of neosartoricin formation|down regulation of neosartoricin synthesis|downregulation of neosartoricin anabolism|inhibition of neosartoricin biosynthesis|down regulation of neosartoricin formation|downregulation of neosartoricin synthesis|downregulation of neosartoricin formation|down-regulation of neosartoricin anabolism|negative regulation of neosartoricin anabolism|down-regulation of neosartoricin biosynthetic process|negative regulation of neosartoricin biosynthesis|down-regulation of neosartoricin biosynthesis|down-regulation of neosartoricin synthesis|negative regulation of neosartoricin synthesis|down-regulation of neosartoricin formation|negative regulation of neosartoricin formation http://purl.obolibrary.org/obo/GO_1902054 GO:0015920 biolink:BiologicalProcess lipopolysaccharide transport The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. go-plus.json LPS transport http://purl.obolibrary.org/obo/GO_0015920 goslim_pir GO:1902055 biolink:BiologicalProcess positive regulation of neosartoricin biosynthetic process Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process. go-plus.json up regulation of neosartoricin biosynthesis|up regulation of neosartoricin biosynthetic process|up-regulation of neosartoricin synthesis|up-regulation of neosartoricin formation|upregulation of neosartoricin anabolism|upregulation of neosartoricin synthesis|upregulation of neosartoricin biosynthesis|upregulation of neosartoricin biosynthetic process|upregulation of neosartoricin formation|up regulation of neosartoricin anabolism|positive regulation of neosartoricin anabolism|up-regulation of neosartoricin biosynthetic process|up-regulation of neosartoricin biosynthesis|up regulation of neosartoricin synthesis|activation of neosartoricin biosynthetic process|positive regulation of neosartoricin synthesis|activation of neosartoricin anabolism|up regulation of neosartoricin formation|positive regulation of neosartoricin formation|activation of neosartoricin biosynthesis|activation of neosartoricin synthesis|up-regulation of neosartoricin anabolism|activation of neosartoricin formation|positive regulation of neosartoricin biosynthesis http://purl.obolibrary.org/obo/GO_1902055 GO:0015921 biolink:BiologicalProcess lipopolysaccharide export The directed movement of lipopolysaccharides out of a cell or organelle. go-plus.json LPS export http://purl.obolibrary.org/obo/GO_0015921 GO:1902052 biolink:MolecularActivity (25S)-Delta(7)-dafachronate binding Binding to (25S)-Delta(7)-dafachronate. go-plus.json http://purl.obolibrary.org/obo/GO_1902052 GO:0015922 biolink:MolecularActivity aspartate oxidase activity Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide. go-plus.json http://purl.obolibrary.org/obo/GO_0015922 GO:1902053 biolink:BiologicalProcess regulation of neosartoricin biosynthetic process Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process. go-plus.json regulation of neosartoricin biosynthesis|regulation of neosartoricin anabolism|regulation of neosartoricin synthesis|regulation of neosartoricin formation http://purl.obolibrary.org/obo/GO_1902053 GO:0015923 biolink:MolecularActivity mannosidase activity Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0015923 GO:1902050 biolink:BiologicalProcess neosartoricin biosynthetic process The chemical reactions and pathways resulting in the formation of neosartoricin. go-plus.json neosartoricin biosynthesis|neosartoricin anabolism|neosartoricin synthesis|neosartoricin formation http://purl.obolibrary.org/obo/GO_1902050 GO:0050290 biolink:MolecularActivity sphingomyelin phosphodiesterase D activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+). RHEA:20984|KEGG_REACTION:R02542|EC:3.1.4.41|MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN go-plus.json sphingomyelinase D|sphingomyelin ceramide-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050290 GO:1902051 biolink:MolecularActivity (25S)-Delta(4)-dafachronate binding Binding to (25S)-Delta(4)-dafachronate. go-plus.json http://purl.obolibrary.org/obo/GO_1902051 GO:0050293 biolink:MolecularActivity steroid-lactonase activity Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate. RHEA:13721|KEGG_REACTION:R03641|MetaCyc:STEROID-LACTONASE-RXN|EC:3.1.1.37 go-plus.json testololactone lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0050293 GO:0050294 biolink:MolecularActivity steroid sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate. MetaCyc:STEROID-SULFOTRANSFERASE-RXN|EC:2.8.2.15|Reactome:R-HSA-176521|Reactome:R-HSA-176517|Reactome:R-HSA-176631 go-plus.json steroid alcohol sulfotransferase|3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity|steroid sulphotransferase activity http://purl.obolibrary.org/obo/GO_0050294 goslim_chembl GO:0050291 biolink:MolecularActivity sphingosine N-acyltransferase activity Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. EC:2.3.1.24|RHEA:23768|Reactome:R-HSA-428185|MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN go-plus.json sphingosine acyltransferase activity|dihydroceramide synthase activity|ceramide synthetase activity|acyl-CoA:sphingosine N-acyltransferase activity|ceramide synthase activity http://purl.obolibrary.org/obo/GO_0050291 CHEBI:37260 biolink:ChemicalSubstance hept-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37260 GO:0050292 biolink:MolecularActivity steroid 9-alpha-monooxygenase activity Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O. RHEA:19557|MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN|KEGG_REACTION:R04392|EC:1.14.99.24 go-plus.json steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)|steroid 9alpha-monooxygenase activity|steroid 9-alpha-hydroxylase activity|steroid 9alpha-hydroxylase activity|steroid 9a-monooxygenase activity http://purl.obolibrary.org/obo/GO_0050292 GO:0050297 biolink:MolecularActivity stizolobate synthase activity Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde. RHEA:21220|EC:1.13.11.29|MetaCyc:STIZOLOBATE-SYNTHASE-RXN go-plus.json 3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing) http://purl.obolibrary.org/obo/GO_0050297 GO:0050298 biolink:MolecularActivity stizolobinate synthase activity Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde. MetaCyc:STIZOLOBINATE-SYNTHASE-RXN|RHEA:18465|EC:1.13.11.30 go-plus.json 3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing) http://purl.obolibrary.org/obo/GO_0050298 GO:0050295 biolink:MolecularActivity steryl-beta-glucosidase activity Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol. RHEA:11956|KEGG_REACTION:R01460|EC:3.2.1.104|MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN go-plus.json cholesteryl-beta-D-glucoside glucohydrolase activity|steryl-b-glucosidase activity http://purl.obolibrary.org/obo/GO_0050295 GO:0050296 biolink:MolecularActivity stipitatonate decarboxylase activity Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate. KEGG_REACTION:R03739|MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN|RHEA:13885|EC:4.1.1.60 go-plus.json stipitatonate carboxy-lyase (decyclizing)|stipitatonate carboxy-lyase (decyclizing, stipitatate-forming) http://purl.obolibrary.org/obo/GO_0050296 GO:1902058 biolink:BiologicalProcess regulation of sporocarp development involved in sexual reproduction Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction. go-plus.json regulation of ascus development|regulation of fruiting body formation involved in sexual reproduction|regulation of perfect stage fruiting body development|regulation of fruiting body development involved in sexual reproduction http://purl.obolibrary.org/obo/GO_1902058 GO:1902059 biolink:BiologicalProcess negative regulation of sporocarp development involved in sexual reproduction Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction. go-plus.json downregulation of ascus development|down regulation of fruiting body formation involved in sexual reproduction|down-regulation of sporocarp development involved in sexual reproduction|negative regulation of fruiting body development involved in sexual reproduction|down-regulation of fruiting body development involved in sexual reproduction|downregulation of fruiting body formation involved in sexual reproduction|inhibition of perfect stage fruiting body development|down-regulation of ascus development|negative regulation of ascus development|inhibition of sporocarp development involved in sexual reproduction|down regulation of perfect stage fruiting body development|down-regulation of fruiting body formation involved in sexual reproduction|negative regulation of fruiting body formation involved in sexual reproduction|inhibition of fruiting body development involved in sexual reproduction|downregulation of perfect stage fruiting body development|down regulation of sporocarp development involved in sexual reproduction|inhibition of ascus development|down regulation of fruiting body development involved in sexual reproduction|down-regulation of perfect stage fruiting body development|negative regulation of perfect stage fruiting body development|downregulation of sporocarp development involved in sexual reproduction|inhibition of fruiting body formation involved in sexual reproduction|downregulation of fruiting body development involved in sexual reproduction|down regulation of ascus development http://purl.obolibrary.org/obo/GO_1902059 UBERON:0010221 biolink:AnatomicalEntity laryngeal associated mesenchyme go-plus.json http://purl.obolibrary.org/obo/UBERON_0010221 GO:1902056 biolink:BiologicalProcess (25S)-Delta(7)-dafachronate metabolic process The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate. go-plus.json (25S)-Delta(7)-dafachronate metabolism http://purl.obolibrary.org/obo/GO_1902056 GO:1902057 biolink:BiologicalProcess (25S)-Delta(4)-dafachronate metabolic process The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate. go-plus.json (25S)-Delta(4)-dafachronate metabolism http://purl.obolibrary.org/obo/GO_1902057 GO:1902065 biolink:BiologicalProcess response to L-glutamate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902065 CHEBI:37237 biolink:ChemicalSubstance elemental molybdenum go-plus.json http://purl.obolibrary.org/obo/CHEBI_37237 GO:1902066 biolink:BiologicalProcess regulation of cell wall pectin metabolic process Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process. go-plus.json regulation of cellulose and pectin-containing cell wall pectin metabolic process|regulation of pectin metabolism during cell wall biogenesis|regulation of plant-type cell wall pectin metabolic process|regulation of cell wall pectin metabolism http://purl.obolibrary.org/obo/GO_1902066 GO:1902063 biolink:BiologicalProcess betaine aldehyde biosynthetic process The chemical reactions and pathways resulting in the formation of betaine aldehyde. go-plus.json betaine aldehyde anabolism|betaine aldehyde synthesis|betaine aldehyde formation|betaine aldehyde biosynthesis http://purl.obolibrary.org/obo/GO_1902063 GO:1902064 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in spermatogenesis Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis. go-plus.json regulation of global transcription from Pol II promoter involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa|regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis|global transcription regulation from Pol II promoter involved in generation of spermatozoa|global transcription regulation from Pol II promoter involved in spermatogenesis|regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of transcription from Pol II promoter involved in generation of spermatozoa|regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of transcription from Pol II promoter involved in spermatogenesis|regulation of global transcription from Pol II promoter involved in generation of spermatozoa http://purl.obolibrary.org/obo/GO_1902064 GO:1902061 biolink:BiologicalProcess betaine aldehyde metabolic process The chemical reactions and pathways involving betaine aldehyde. go-plus.json betaine aldehyde metabolism http://purl.obolibrary.org/obo/GO_1902061 GO:1902062 biolink:BiologicalProcess betaine aldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of betaine aldehyde. go-plus.json betaine aldehyde catabolism|betaine aldehyde degradation|betaine aldehyde breakdown http://purl.obolibrary.org/obo/GO_1902062 CHEBI:37239 biolink:ChemicalSubstance molybdenum cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_37239 GO:1902060 biolink:BiologicalProcess positive regulation of sporocarp development involved in sexual reproduction Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction. go-plus.json up regulation of perfect stage fruiting body development|upregulation of fruiting body development involved in sexual reproduction|positive regulation of perfect stage fruiting body development|up-regulation of fruiting body formation involved in sexual reproduction|upregulation of ascus development|activation of perfect stage fruiting body development|up regulation of sporocarp development involved in sexual reproduction|activation of sporocarp development involved in sexual reproduction|up regulation of fruiting body development involved in sexual reproduction|upregulation of fruiting body formation involved in sexual reproduction|positive regulation of fruiting body development involved in sexual reproduction|up-regulation of perfect stage fruiting body development|up regulation of ascus development|activation of fruiting body development involved in sexual reproduction|positive regulation of ascus development|up regulation of fruiting body formation involved in sexual reproduction|up-regulation of sporocarp development involved in sexual reproduction|upregulation of perfect stage fruiting body development|positive regulation of fruiting body formation involved in sexual reproduction|activation of ascus development|up-regulation of fruiting body development involved in sexual reproduction|activation of fruiting body formation involved in sexual reproduction|up-regulation of ascus development|upregulation of sporocarp development involved in sexual reproduction http://purl.obolibrary.org/obo/GO_1902060 GO:0015906 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015906 GO:0015907 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015907 GO:0015908 biolink:BiologicalProcess fatty acid transport The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0015908 GO:0015909 biolink:BiologicalProcess long-chain fatty acid transport The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json http://purl.obolibrary.org/obo/GO_0015909 GO:0015902 biolink:BiologicalProcess carbonyl cyanide m-chlorophenylhydrazone transport The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes. go-plus.json CCCP transport http://purl.obolibrary.org/obo/GO_0015902 GO:1902069 biolink:BiologicalProcess negative regulation of sphingolipid mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling. go-plus.json downregulation of sphingolipid signaling pathway|downregulation of sphingolipid mediated signaling pathway|down regulation of sphingolipid signaling pathway|down-regulation of sphingolipid mediated signaling pathway|inhibition of sphingolipid signaling pathway|inhibition of sphingolipid mediated signaling pathway|down-regulation of sphingolipid signaling pathway|negative regulation of sphingolipid signaling pathway|down regulation of sphingolipid mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902069 UBERON:0010212 biolink:AnatomicalEntity laryngeal apparatus Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring. go-plus.json laryngeal cartilage system http://purl.obolibrary.org/obo/UBERON_0010212 GO:0015903 biolink:BiologicalProcess fluconazole transport The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections. go-plus.json http://purl.obolibrary.org/obo/GO_0015903 UBERON:0010213 biolink:AnatomicalEntity laryngeal pre-cartilage condensation go-plus.json http://purl.obolibrary.org/obo/UBERON_0010213 UBERON:0010210 biolink:AnatomicalEntity blood clot A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network. go-plus.json coagulated blood|clot|thrombus|hemostatic plug|fibrin clot http://purl.obolibrary.org/obo/UBERON_0010210 GO:1902067 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902067 GO:0015904 biolink:BiologicalProcess tetracycline transmembrane transport The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). go-plus.json tetracyclin transport|tetracycline transport http://purl.obolibrary.org/obo/GO_0015904 GO:1902068 biolink:BiologicalProcess regulation of sphingolipid mediated signaling pathway Any process that modulates the frequency, rate or extent of sphingolipid signaling. go-plus.json regulation of sphingolipid signaling pathway http://purl.obolibrary.org/obo/GO_1902068 GO:0015905 biolink:BiologicalProcess bicyclomycin transmembrane transport The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive. go-plus.json bicyclomycin transport http://purl.obolibrary.org/obo/GO_0015905 CHEBI:37248 biolink:ChemicalSubstance 3-hydroxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37248 GO:1902076 biolink:BiologicalProcess regulation of lateral motor column neuron migration Any process that modulates the frequency, rate or extent of lateral motor column neuron migration. go-plus.json http://purl.obolibrary.org/obo/GO_1902076 GO:1902077 biolink:BiologicalProcess negative regulation of lateral motor column neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration. go-plus.json down-regulation of lateral motor column neuron migration|inhibition of lateral motor column neuron migration|down regulation of lateral motor column neuron migration|downregulation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1902077 GO:1902074 biolink:BiologicalProcess response to salt Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. go-plus.json response to salinity http://purl.obolibrary.org/obo/GO_1902074 GO:0015900 biolink:BiologicalProcess benomyl transport The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit. go-plus.json http://purl.obolibrary.org/obo/GO_0015900 CHEBI:37246 biolink:ChemicalSubstance elemental sodium go-plus.json http://purl.obolibrary.org/obo/CHEBI_37246 GO:0015901 biolink:BiologicalProcess cycloheximide transport The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0015901 GO:1902075 biolink:BiologicalProcess cellular response to salt Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. go-plus.json cellular response to salinity http://purl.obolibrary.org/obo/GO_1902075 UBERON:0010204 biolink:AnatomicalEntity tail vasculature A vasculature that is part of a post-anal tail. go-plus.json post-vent vasculature|tail vasculature http://purl.obolibrary.org/obo/UBERON_0010204 CHEBI:37247 biolink:ChemicalSubstance elemental potassium go-plus.json http://purl.obolibrary.org/obo/CHEBI_37247 GO:1902072 biolink:BiologicalProcess negative regulation of hypoxia-inducible factor-1alpha signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. go-plus.json inhibition of hypoxia-inducible factor-1alpha signalling pathway|inhibition of HIF1alpha pathway|down regulation of hypoxia-inducible factor-1alpha signaling pathway|downregulation of hypoxia-inducible factor-1alpha signaling pathway|down regulation of HIF1alpha pathway|negative regulation of hypoxia-inducible factor-1alpha signalling pathway|down-regulation of hypoxia-inducible factor-1alpha signalling pathway|downregulation of HIF1alpha pathway|down-regulation of hypoxia-inducible factor-1alpha signaling pathway|downregulation of hypoxia-inducible factor-1alpha signalling pathway|negative regulation of HIF1alpha pathway|down-regulation of HIF1alpha pathway|inhibition of hypoxia-inducible factor-1alpha signaling pathway|down regulation of hypoxia-inducible factor-1alpha signalling pathway http://purl.obolibrary.org/obo/GO_1902072 GO:1902073 biolink:BiologicalProcess positive regulation of hypoxia-inducible factor-1alpha signaling pathway Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. go-plus.json up-regulation of HIF1alpha pathway|upregulation of hypoxia-inducible factor-1alpha signaling pathway|up-regulation of hypoxia-inducible factor-1alpha signalling pathway|upregulation of HIF1alpha pathway|activation of hypoxia-inducible factor-1alpha signalling pathway|up regulation of hypoxia-inducible factor-1alpha signaling pathway|activation of hypoxia-inducible factor-1alpha signaling pathway|positive regulation of hypoxia-inducible factor-1alpha signalling pathway|up regulation of HIF1alpha pathway|up regulation of hypoxia-inducible factor-1alpha signalling pathway|positive regulation of HIF1alpha pathway|hypoxic stabilization of HIF1A|activation of HIF1alpha pathway|up-regulation of hypoxia-inducible factor-1alpha signaling pathway|upregulation of hypoxia-inducible factor-1alpha signalling pathway http://purl.obolibrary.org/obo/GO_1902073 GO:1902070 biolink:BiologicalProcess positive regulation of sphingolipid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of sphingolipid signaling. go-plus.json activation of sphingolipid signaling pathway|upregulation of sphingolipid mediated signaling pathway|positive regulation of sphingolipid signaling pathway|up regulation of sphingolipid signaling pathway|up regulation of sphingolipid mediated signaling pathway|activation of sphingolipid mediated signaling pathway|upregulation of sphingolipid signaling pathway|up-regulation of sphingolipid signaling pathway|up-regulation of sphingolipid mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902070 UBERON:0010207 biolink:AnatomicalEntity nictitating membrane A fold of the mucous membrane of the conjunctiva in many animals. At rest, it is hidden in the medial canthus. It can extend to cover part or all of the cornea to help clean the cornea. go-plus.json membrana nictitans|palperbra tertia|haw|nictitans|third eyelid http://purl.obolibrary.org/obo/UBERON_0010207 GO:1902071 biolink:BiologicalProcess regulation of hypoxia-inducible factor-1alpha signaling pathway Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. go-plus.json regulation of HIF1alpha pathway|regulation of hypoxia-inducible factor-1alpha signalling pathway http://purl.obolibrary.org/obo/GO_1902071 CHEBI:37240 biolink:ChemicalSubstance adenosine 3',5'-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37240 CHEBI:13253 biolink:ChemicalSubstance Asp-tRNA(Asx) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13253 CHEBI:37245 biolink:ChemicalSubstance (E)-3-methylglutaconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37245 CHEBI:52857 biolink:ChemicalSubstance S-sulfanylglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_52857 CHEBI:52859 biolink:ChemicalSubstance choline hydrogen sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52859 CHEBI:27897 biolink:ChemicalSubstance tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27897 CHEBI:27898 biolink:ChemicalSubstance cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_27898 CHEBI:27899 biolink:ChemicalSubstance cisplatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27899 CHEBI:27895 biolink:ChemicalSubstance 2-chloro-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27895 UBERON:0010202 biolink:AnatomicalEntity lateral line The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. go-plus.json lateral lines http://purl.obolibrary.org/obo/UBERON_0010202 GO:1902078 biolink:BiologicalProcess positive regulation of lateral motor column neuron migration Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration. go-plus.json up-regulation of lateral motor column neuron migration|upregulation of lateral motor column neuron migration|up regulation of lateral motor column neuron migration|activation of lateral motor column neuron migration http://purl.obolibrary.org/obo/GO_1902078 GO:1902079 biolink:BiologicalProcess D-valine catabolic process The chemical reactions and pathways resulting in the breakdown of D-valine. go-plus.json D-valine degradation|D-valine breakdown|D-valine catabolism http://purl.obolibrary.org/obo/GO_1902079 CHEBI:27891 biolink:ChemicalSubstance S-sulfo-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27891 GO:1902087 biolink:BiologicalProcess dimethylsulfoniopropionate catabolic process The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin. go-plus.json S,S-dimethyl-beta-propiothetin catabolic process|S,S-dimethyl-beta-propiothetin degradation|S,S-dimethyl-beta-propiothetin breakdown|S,S-dimethyl-beta-propiothetin catabolism http://purl.obolibrary.org/obo/GO_1902087 GO:1902088 biolink:BiologicalProcess plant-type cell wall loosening involved in abscission Any plant-type cell wall loosening that is involved in abscission. go-plus.json cellulose and pectin-containing cell wall loosening involved in abscission http://purl.obolibrary.org/obo/GO_1902088 GO:1902085 biolink:BiologicalProcess fumagillin catabolic process The chemical reactions and pathways resulting in the breakdown of fumagillin. go-plus.json fumagillin catabolism|fumagillin degradation|fumagillin breakdown http://purl.obolibrary.org/obo/GO_1902085 GO:1902086 biolink:BiologicalProcess fumagillin biosynthetic process The chemical reactions and pathways resulting in the formation of fumagillin. go-plus.json fumagillin anabolism|fumagillin biosynthesis|fumagillin synthesis|fumagillin formation http://purl.obolibrary.org/obo/GO_1902086 NCBITaxon:1804623 biolink:OrganismalEntity Chenopodiaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1804623 GO:1902083 biolink:BiologicalProcess negative regulation of peptidyl-cysteine S-nitrosylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. go-plus.json down-regulation of peptidyl-cysteine S-nitrosylation|inhibition of protein S-nitrosylation|inhibition of S-nitrosylation|inhibition of peptidyl-cysteine S-nitrosylation|down regulation of protein S-nitrosylation|down regulation of S-nitrosylation|downregulation of protein S-nitrosylation|downregulation of S-nitrosylation|down regulation of peptidyl-cysteine S-nitrosylation|negative regulation of protein S-nitrosylation|down-regulation of protein S-nitrosylation|downregulation of peptidyl-cysteine S-nitrosylation|down-regulation of S-nitrosylation|negative regulation of S-nitrosylation http://purl.obolibrary.org/obo/GO_1902083 GO:1902084 biolink:BiologicalProcess fumagillin metabolic process The chemical reactions and pathways involving fumagillin. go-plus.json fumagillin metabolism http://purl.obolibrary.org/obo/GO_1902084 GO:1902081 biolink:BiologicalProcess negative regulation of calcium ion import into sarcoplasmic reticulum Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum. go-plus.json down-regulation of calcium ion import into sarcoplasmic reticulum|downregulation of calcium ion import into sarcoplasmic reticulum|down regulation of calcium ion import into sarcoplasmic reticulum|inhibition of calcium ion import into sarcoplasmic reticulum http://purl.obolibrary.org/obo/GO_1902081 GO:1902082 biolink:BiologicalProcess positive regulation of calcium ion import into sarcoplasmic reticulum Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum. go-plus.json up regulation of calcium ion import into sarcoplasmic reticulum|upregulation of calcium ion import into sarcoplasmic reticulum|up-regulation of calcium ion import into sarcoplasmic reticulum|activation of calcium ion import into sarcoplasmic reticulum http://purl.obolibrary.org/obo/GO_1902082 GO:1902080 biolink:BiologicalProcess regulation of calcium ion import into sarcoplasmic reticulum Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_1902080 UBERON:0009210 biolink:AnatomicalEntity pharyngeal membrane A thin fold of ectoderm and endoderm that separates the pharyngeal pouches from the pharyngeal clefts in a developing embryo. go-plus.json pharyngeal membrane|branchial membrane|branchial arch membrane http://purl.obolibrary.org/obo/UBERON_0009210 UBERON:0009213 biolink:AnatomicalEntity pharyngeal membrane of 1st arch A pharyngeal membrane that separates the first pharyngeal cleft from the first pharyngeal pouch. go-plus.json future tympanic membrane|tympanic membrane primordium|1st pharyngeal membrane|1st branchial membrane http://purl.obolibrary.org/obo/UBERON_0009213 CHEBI:52845 biolink:ChemicalSubstance cyclic organic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_52845 GO:1902089 biolink:BiologicalProcess cell wall polysaccharide catabolic process involved in lateral root development Any cell wall polysaccharide catabolic process that is involved in lateral root development. go-plus.json cell wall polysaccharide breakdown involved in lateral root development http://purl.obolibrary.org/obo/GO_1902089 GO:1902098 biolink:MolecularActivity calcitriol binding Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3. go-plus.json hormonally active vitamin D3 binding|1,25-dihydroxycholecalciferol binding|1,25-dihydroxyvitamin D3 binding|1alpha,25-dihydroxyvitamin D3 binding|1alpha,25-dihydroxycholecalciferol binding|1alpha,25(OH)2D3 binding|1alpha,25(OH)2 vitamin D3 binding http://purl.obolibrary.org/obo/GO_1902098 UBERON:0009205 biolink:AnatomicalEntity lateral nasal process mesenchyme Mesenchyme that is part of a lateral nasal prominence. go-plus.json mesenchyme of latero-nasal process http://purl.obolibrary.org/obo/UBERON_0009205 GO:1902099 biolink:BiologicalProcess regulation of metaphase/anaphase transition of cell cycle Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1902099 UBERON:0009206 biolink:AnatomicalEntity lateral nasal process surface ectoderm An ectoderm that is part of a lateral nasal prominence. go-plus.json ectoderm of latero-nasal process http://purl.obolibrary.org/obo/UBERON_0009206 GO:1902096 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902096 GO:1902097 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium. go-plus.json up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up-regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria http://purl.obolibrary.org/obo/GO_1902097 GO:1902094 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902094 GO:1902095 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902095 GO:1902092 biolink:BiologicalProcess positive regulation of fumagillin biosynthetic process Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process. go-plus.json upregulation of fumagillin anabolism|upregulation of fumagillin synthesis|up regulation of fumagillin biosynthesis|up regulation of fumagillin biosynthetic process|upregulation of fumagillin formation|activation of fumagillin biosynthetic process|positive regulation of fumagillin biosynthesis|up-regulation of fumagillin anabolism|activation of fumagillin biosynthesis|up-regulation of fumagillin synthesis|activation of fumagillin anabolism|up-regulation of fumagillin formation|up-regulation of fumagillin biosynthetic process|activation of fumagillin synthesis|up-regulation of fumagillin biosynthesis|positive regulation of fumagillin anabolism|up regulation of fumagillin anabolism|activation of fumagillin formation|positive regulation of fumagillin synthesis|up regulation of fumagillin synthesis|positive regulation of fumagillin formation|upregulation of fumagillin biosynthetic process|upregulation of fumagillin biosynthesis|up regulation of fumagillin formation http://purl.obolibrary.org/obo/GO_1902092 GO:1902093 biolink:BiologicalProcess positive regulation of flagellated sperm motility Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. go-plus.json up-regulation of sperm motility|upregulation of sperm movement|up-regulation of sperm movement|up regulation of sperm motility|activation of sperm movement|activation of sperm motility|positive regulation of sperm movement|upregulation of sperm motility|up regulation of sperm movement|positive regulation of sperm motility http://purl.obolibrary.org/obo/GO_1902093 GO:1902090 biolink:BiologicalProcess regulation of fumagillin biosynthetic process Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process. go-plus.json regulation of fumagillin synthesis|regulation of fumagillin biosynthesis|regulation of fumagillin formation|regulation of fumagillin anabolism http://purl.obolibrary.org/obo/GO_1902090 GO:1902091 biolink:BiologicalProcess negative regulation of fumagillin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process. go-plus.json down regulation of fumagillin biosynthetic process|down regulation of fumagillin biosynthesis|downregulation of fumagillin formation|down regulation of fumagillin synthesis|downregulation of fumagillin biosynthetic process|downregulation of fumagillin biosynthesis|down regulation of fumagillin formation|inhibition of fumagillin anabolism|inhibition of fumagillin synthesis|inhibition of fumagillin formation|down-regulation of fumagillin biosynthesis|negative regulation of fumagillin biosynthesis|down-regulation of fumagillin biosynthetic process|negative regulation of fumagillin anabolism|down-regulation of fumagillin anabolism|inhibition of fumagillin biosynthetic process|negative regulation of fumagillin synthesis|down-regulation of fumagillin synthesis|negative regulation of fumagillin formation|down-regulation of fumagillin formation|inhibition of fumagillin biosynthesis|downregulation of fumagillin anabolism|downregulation of fumagillin synthesis|down regulation of fumagillin anabolism http://purl.obolibrary.org/obo/GO_1902091 UBERON:0009200 biolink:AnatomicalEntity limb epidermis The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009200 UBERON:0009201 biolink:AnatomicalEntity nephric duct A nephric duct is a tube that drains a primitive kidney[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009201 UBERON:0009203 biolink:AnatomicalEntity internasal suture A suture joining the nasal bones. go-plus.json nasal suture|inter-nasal suture|internasal suture of skull|sutura internasalis|sutura internasalis http://purl.obolibrary.org/obo/UBERON_0009203 UBERON:0009204 biolink:AnatomicalEntity medial nasal process mesenchyme Mesenchyme that is part of a medial nasal prominence. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009204 CL:0000127 biolink:Cell astrocyte A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. go-plus.json astrocytic glia http://purl.obolibrary.org/obo/CL_0000127 CL:0000128 biolink:Cell oligodendrocyte A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. go-plus.json OLs|oligodendroglia http://purl.obolibrary.org/obo/CL_0000128 CL:0000129 biolink:Cell microglial cell A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. go-plus.json brain macrophage|microgliocyte|brain-resident macrophage|hortega cells|MF.microglia.CNS|microglia http://purl.obolibrary.org/obo/CL_0000129 GO:0015898 biolink:BiologicalProcess amiloride transport The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic. go-plus.json http://purl.obolibrary.org/obo/GO_0015898 GO:0015899 biolink:BiologicalProcess aminotriazole transport The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity. go-plus.json http://purl.obolibrary.org/obo/GO_0015899 CL:0000120 biolink:Cell granule cell go-plus.json http://purl.obolibrary.org/obo/CL_0000120 CL:0000121 biolink:Cell Purkinje cell The output neuron of the cerebellar cortex. go-plus.json Purkinje neuron|cerebellum Purkinje cell|cerebellar Purkinje cell|Purkinje's cell http://purl.obolibrary.org/obo/CL_0000121 CL:0000122 biolink:Cell stellate neuron A neuron that has dendritic processes radiating from the cell body forming a star-like shape. go-plus.json http://purl.obolibrary.org/obo/CL_0000122 GO:0015894 biolink:BiologicalProcess acriflavine transport The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication. go-plus.json acriflavin transport http://purl.obolibrary.org/obo/GO_0015894 CL:0000123 biolink:Cell neuron associated cell (sensu Vertebrata) go-plus.json http://purl.obolibrary.org/obo/CL_0000123 GO:0015895 biolink:BiologicalProcess alkane transport The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0015895 CL:0000125 biolink:Cell glial cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. go-plus.json neuroglia|neuroglial cell http://purl.obolibrary.org/obo/CL_0000125 GO:0015896 biolink:BiologicalProcess nalidixic acid transport The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication. go-plus.json http://purl.obolibrary.org/obo/GO_0015896 CL:0000126 biolink:Cell macroglial cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. go-plus.json macrogliocyte http://purl.obolibrary.org/obo/CL_0000126 GO:0015897 biolink:BiologicalProcess organomercurial transport The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom. go-plus.json http://purl.obolibrary.org/obo/GO_0015897 GO:0015890 biolink:BiologicalProcess nicotinamide mononucleotide transport The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP. go-plus.json nicotinamide ribonucleotide transport http://purl.obolibrary.org/obo/GO_0015890 GO:0015891 biolink:BiologicalProcess siderophore transport The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json siderophore-iron transport|iron-siderochrome transport|siderochrome transport|iron-siderophore transport http://purl.obolibrary.org/obo/GO_0015891 goslim_pir GO:0015892 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015892 GO:0015893 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015893 CHEBI:86160 biolink:ChemicalSubstance (2E)-pentenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86160 chebi_ph7_3 CHEBI:86162 biolink:ChemicalSubstance 1-tetradecanoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86162 chebi_ph7_3 CL:0000138 biolink:Cell chondrocyte Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. go-plus.json cartilage cell http://purl.obolibrary.org/obo/CL_0000138 CHEBI:86165 biolink:ChemicalSubstance (24S,25S)-cholest-5-en-3beta,24,26-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86165 chebi_ph7_3 CL:0000133 biolink:Cell neurectodermal cell Ectoderm destined to be nervous tissue. go-plus.json neurectoderm cell http://purl.obolibrary.org/obo/CL_0000133 CL:0000134 biolink:Cell mesenchymal stem cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. go-plus.json BMSC|mesenchymal precursor cell|mesenchymal stem cell|mesenchymal stromal cell|MSC|stem cells, mesenchymal|colony-forming unit-fibroblast|mesenchymal progenitor cells|mesenchymal stromal cells|marrow stromal cells|bone marrow stromal cells|CFU-F http://purl.obolibrary.org/obo/CL_0000134 CL:0000135 biolink:Cell fibrocyte An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes. go-plus.json http://purl.obolibrary.org/obo/CL_0000135 CL:0000136 biolink:Cell fat cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. go-plus.json adipocyte|adipose cell http://purl.obolibrary.org/obo/CL_0000136 GO:0050202 biolink:MolecularActivity octopamine dehydratase activity Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+). MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN|EC:4.2.1.87|KEGG_REACTION:R03358|RHEA:18173 go-plus.json octopamine hydro-lyase (deaminating)|octopamine hydrolyase activity|octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming] http://purl.obolibrary.org/obo/GO_0050202 GO:0050203 biolink:MolecularActivity oxalate-CoA ligase activity Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA. KEGG_REACTION:R01558|EC:6.2.1.8|MetaCyc:OXALATE--COA-LIGASE-RXN|RHEA:18293 go-plus.json oxalyl coenzyme A synthetase activity|oxalate:CoA ligase (AMP-forming)|oxalyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0050203 GO:0050200 biolink:MolecularActivity plasmalogen synthase activity Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine. EC:2.3.1.25|MetaCyc:PLASMALOGEN-SYNTHASE-RXN go-plus.json 1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity|lysoplasmenylcholine acyltransferase activity|acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity|O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity http://purl.obolibrary.org/obo/GO_0050200 GO:0050201 biolink:MolecularActivity fucokinase activity Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+). Reactome:R-HSA-6787540|MetaCyc:FUCOKINASE-RXN|EC:2.7.1.52|RHEA:13241|KEGG_REACTION:R03161 go-plus.json L-fucokinase activity|fucokinase (phosphorylating) activity|L-fucose kinase activity|fucose kinase activity|ATP:6-deoxy-L-galactose 1-phosphotransferase activity|ATP:beta-L-fucose 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050201 GO:0050206 biolink:MolecularActivity oximinotransferase activity Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate. RHEA:11624|KEGG_REACTION:R03796|EC:2.6.3.1|MetaCyc:OXIMINOTRANSFERASE-RXN go-plus.json transoximase activity|oximinotransaminase activity|oximase activity|transoximinase activity|pyruvate-acetone oximinotransferase activity http://purl.obolibrary.org/obo/GO_0050206 GO:0050207 biolink:MolecularActivity plasmanylethanolamine desaturase activity Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O. EC:1.14.19.77|RHEA:22956|MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN go-plus.json 1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity|plasmenylethanolamine desaturase activity|O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity|alkylacylglycero-phosphorylethanolamine dehydrogenase activity|alkylacylglycerophosphoethanolamine desaturase activity|dehydrogenase, alkyl-acylglycerophosphorylethanolamine|1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity http://purl.obolibrary.org/obo/GO_0050207 GO:0050204 biolink:MolecularActivity oxalomalate lyase activity Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate. EC:4.1.3.13|KEGG_REACTION:R00477|RHEA:22032|MetaCyc:OXALOMALATE-LYASE-RXN go-plus.json 3-oxalomalate glyoxylate-lyase activity|3-oxalomalate glyoxylate-lyase (oxaloacetate-forming) http://purl.obolibrary.org/obo/GO_0050204 GO:0050205 biolink:MolecularActivity oxamate carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate. KEGG_REACTION:R02937|RHEA:22984|EC:2.1.3.5|MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN go-plus.json carbamoyl-phosphate:oxamate carbamoyltransferase activity|oxamic transcarbamylase activity http://purl.obolibrary.org/obo/GO_0050205 CL:0000106 biolink:Cell unipolar neuron Neuron with one neurite that extends from the cell body. go-plus.json http://purl.obolibrary.org/obo/CL_0000106 GO:0050208 biolink:MolecularActivity polysialic-acid O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9. RHEA:11604|MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.136 go-plus.json acetyl-CoA:polysialic-acid O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050208 CL:0000107 biolink:Cell autonomic neuron A neruon whose cell body is within an autonomic ganglion. go-plus.json http://purl.obolibrary.org/obo/CL_0000107 GO:0050209 biolink:MolecularActivity polyvinyl-alcohol oxidase activity Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2. RHEA:21688|EC:1.1.3.30|MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN go-plus.json polyvinyl-alcohol:oxygen oxidoreductase activity|dehydrogenase, polyvinyl alcohol|PVA oxidase activity http://purl.obolibrary.org/obo/GO_0050209 CL:0000108 biolink:Cell cholinergic neuron A neuron that uses acetylcholine as a vesicular neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/CL_0000108 GO:0015876 biolink:BiologicalProcess acetyl-CoA transport The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0015876 GO:0015877 biolink:BiologicalProcess biopterin transport The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0015877 GO:0015878 biolink:BiologicalProcess biotin transport The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. go-plus.json vitamin B7 transport|vitamin H transport http://purl.obolibrary.org/obo/GO_0015878 GO:0015879 biolink:BiologicalProcess carnitine transport The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. go-plus.json vitamin Bt transport http://purl.obolibrary.org/obo/GO_0015879 CL:0000100 biolink:Cell motor neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. go-plus.json motoneuron http://purl.obolibrary.org/obo/CL_0000100 GO:0015872 biolink:BiologicalProcess dopamine transport The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. go-plus.json http://purl.obolibrary.org/obo/GO_0015872 CL:0000101 biolink:Cell sensory neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. go-plus.json http://purl.obolibrary.org/obo/CL_0000101 GO:0015873 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015873 GO:0015874 biolink:BiologicalProcess norepinephrine transport The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. go-plus.json levarterenol transport|noradrenaline transport http://purl.obolibrary.org/obo/GO_0015874 CL:0000103 biolink:Cell bipolar neuron A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. go-plus.json http://purl.obolibrary.org/obo/CL_0000103 GO:0015875 biolink:BiologicalProcess obsolete vitamin or cofactor transport OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells. go-plus.json vitamin or cofactor transport http://purl.obolibrary.org/obo/GO_0015875 GO:0015870 biolink:BiologicalProcess acetylcholine transport The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0015870 GO:0015871 biolink:BiologicalProcess choline transport The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. go-plus.json http://purl.obolibrary.org/obo/GO_0015871 GO:0050213 biolink:MolecularActivity progesterone 5-alpha-reductase activity Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH. RHEA:21952|EC:1.3.1.30|MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN go-plus.json delta4-steroid 5alpha-reductase (progesterone)|progesterone 5alpha-reductase activity|progesterone 5a-reductase activity|5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity|steroid 5-alpha-reductase activity http://purl.obolibrary.org/obo/GO_0050213 GO:0050214 biolink:MolecularActivity progesterone monooxygenase activity Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate. MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN|EC:1.14.99.4|RHEA:11984|KEGG_REACTION:R02212 go-plus.json progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|progesterone hydroxylase activity http://purl.obolibrary.org/obo/GO_0050214 GO:0050211 biolink:MolecularActivity procollagen galactosyltransferase activity Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine. MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN|RHEA:12637|Reactome:R-HSA-1981120|Reactome:R-HSA-1981128|EC:2.4.1.50 go-plus.json uridine diphosphogalactose-collagen galactosyltransferase activity|UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|UDP galactose-collagen galactosyltransferase activity|hydroxylysine galactosyltransferase activity|collagen hydroxylysyl galactosyltransferase activity|UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity|UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|collagen galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0050211 GO:0050212 biolink:MolecularActivity progesterone 11-alpha-monooxygenase activity Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O. EC:1.14.99.14|MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN|KEGG_REACTION:R02214|RHEA:18205 go-plus.json progesterone 11a-monooxygenase activity|progesterone 11alpha-monooxygenase activity|progesterone 11-alpha-hydroxylase activity|progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)|progesterone 11alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050212 GO:0050217 biolink:MolecularActivity propioin synthase activity Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal. MetaCyc:PROPIOIN-SYNTHASE-RXN|EC:4.1.2.35|KEGG_REACTION:R00038|RHEA:11100 go-plus.json 4-hydroxy-3-hexanone propanal-lyase activity|4-hydroxy-3-hexanone aldolase activity|4-hydroxy-3-hexanone propanal-lyase (propanal-forming) http://purl.obolibrary.org/obo/GO_0050217 GO:0050218 biolink:MolecularActivity propionate-CoA ligase activity Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA. MetaCyc:PROPIONATE--COA-LIGASE-RXN|EC:6.2.1.17|RHEA:20373 go-plus.json propionyl-CoA synthetase activity|propanoate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0050218 GO:0050215 biolink:MolecularActivity propanediol dehydratase activity Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal. EC:4.2.1.28|MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN|RHEA:14569|KEGG_REACTION:R02376 go-plus.json adenosylcobalamin-dependent diol dehydratase activity|1,2-propanediol dehydratase activity|diol dehydratase activity|DL-1,2-propanediol hydro-lyase activity|propanediol dehydrase activity|propane-1,2-diol hydro-lyase (propanal-forming)|coenzyme B12-dependent diol dehydrase activity|diol dehydrase activity|meso-2,3-butanediol dehydrase activity|propane-1,2-diol hydro-lyase activity|dioldehydratase activity http://purl.obolibrary.org/obo/GO_0050215 GO:0050216 biolink:MolecularActivity propanediol-phosphate dehydrogenase activity Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH. EC:1.1.1.7|MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN|KEGG_REACTION:R04236|RHEA:21584 go-plus.json http://purl.obolibrary.org/obo/GO_0050216 CL:0000117 biolink:Cell CNS neuron (sensu Vertebrata) go-plus.json http://purl.obolibrary.org/obo/CL_0000117 GO:0050219 biolink:MolecularActivity prostaglandin-A1 delta-isomerase activity Catalysis of the reaction: prostaglandin A1 = prostaglandin C1. MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN|EC:5.3.3.9|KEGG_REACTION:R04565|RHEA:10460 go-plus.json prostaglandin-A1 D-isomerase activity|prostaglandin A isomerase activity|(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity http://purl.obolibrary.org/obo/GO_0050219 CL:0000119 biolink:Cell cerebellar Golgi cell Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell enters ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004. go-plus.json cerebellum Golgi cell|cerebellar Golgi neuron|Golgi cell|Golgi neuron http://purl.obolibrary.org/obo/CL_0000119 GO:0015887 biolink:BiologicalProcess pantothenate transmembrane transport The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. go-plus.json pantothenate membrane transport|vitamin B5 transport|pantothenate transport http://purl.obolibrary.org/obo/GO_0015887 GO:0015888 biolink:BiologicalProcess thiamine transport The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. go-plus.json thiamin transport|vitamin B1 transport http://purl.obolibrary.org/obo/GO_0015888 GO:0015889 biolink:BiologicalProcess cobalamin transport The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json vitamin B12 transport http://purl.obolibrary.org/obo/GO_0015889 GO:0015883 biolink:BiologicalProcess FAD transport The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. go-plus.json flavin-adenine dinucleotide transport|flavin adenine dinucleotide transport http://purl.obolibrary.org/obo/GO_0015883 GO:0015884 biolink:BiologicalProcess folic acid transport The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. go-plus.json folate transport|vitamin B9 transport|vitamin M transport http://purl.obolibrary.org/obo/GO_0015884 CL:0000114 biolink:Cell surface ectodermal cell go-plus.json surface ectoderm cell|cell of surface ectoderm http://purl.obolibrary.org/obo/CL_0000114 GO:0015885 biolink:BiologicalProcess 5-formyltetrahydrofolate transport The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015885 GO:0015886 biolink:BiologicalProcess heme transport The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json haem transport http://purl.obolibrary.org/obo/GO_0015886 CL:0000115 biolink:Cell endothelial cell An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. go-plus.json endotheliocyte http://purl.obolibrary.org/obo/CL_0000115 GO:0015880 biolink:BiologicalProcess coenzyme A transport The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. go-plus.json http://purl.obolibrary.org/obo/GO_0015880 GO:0015881 biolink:BiologicalProcess creatine transmembrane transport The directed movement of creatine across a membrane. go-plus.json creatine transport http://purl.obolibrary.org/obo/GO_0015881 GO:0015882 biolink:BiologicalProcess L-ascorbic acid transmembrane transport The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species. go-plus.json vitamin C transport|L-ascorbic acid transport|L-ascorbate transport http://purl.obolibrary.org/obo/GO_0015882 GO:0050210 biolink:MolecularActivity prenyl-diphosphatase activity Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate. RHEA:21496|EC:3.1.7.1|MetaCyc:PRENYL-PYROPHOSPHATASE-RXN go-plus.json prenyl-diphosphate diphosphohydrolase activity|prenyl-pyrophosphatase activity|prenol pyrophosphatase activity|prenylphosphatase activity http://purl.obolibrary.org/obo/GO_0050210 GO:0001213 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001213 GO:0050224 biolink:MolecularActivity prunasin beta-glucosidase activity Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile. KEGG_REACTION:R02558|EC:3.2.1.118|RHEA:16489|MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN go-plus.json prunasin hydrolase activity|prunasin b-glucosidase activity|prunasin beta-D-glucohydrolase activity http://purl.obolibrary.org/obo/GO_0050224 UBERON:0000934 biolink:AnatomicalEntity ventral nerve cord The pair of closely united ventral longitudinal nerves with their segmental ganglia that is characteristic of many elongate invertebrates (as earthworms)[BTO]. A large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring[WB]. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms[GO]. go-plus.json ventral cord http://purl.obolibrary.org/obo/UBERON_0000934 GO:0050225 biolink:MolecularActivity pseudouridine kinase activity Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate. RHEA:22448|KEGG_REACTION:R03315|EC:2.7.1.83|MetaCyc:PSEUDOURIDINE-KINASE-RXN go-plus.json pseudouridine kinase (phosphorylating)|ATP:pseudouridine 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050225 GO:0001214 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001214 UBERON:0000935 biolink:AnatomicalEntity anterior commissure A bundle of myelinated nerve fibers passing transversely through the lamina terminalis and connecting symmetrical parts of the two cerebral hemispheres; it consists of a smaller anterior part (pars anterior commissurae anterioris) and a larger posterior part (pars posterior commissurae anterioris). go-plus.json commissura rostral|AC|commissura anterior cerebri|anterior cerebral commissure|commissura rostralis|paleocortical commissure|commissura anterior|anterior commissural nucleus|precommisure|rostral commissure http://purl.obolibrary.org/obo/UBERON_0000935 GO:0001215 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001215 UBERON:0000936 biolink:AnatomicalEntity posterior commissure Rounded band of white fibers crossing the middle line on the dorsal aspect of the upper end of the cerebral aqueduct. It is important in the bilateral pupillary light reflex. Its fibers acquire their medullary sheaths early, but their connections have not been definitely determined. Most of them have their origin in a nucleus, the nucleus of the posterior commissure (nucleus of Darkschewitsch), which lies in the central gray substance of the upper end of the cerebral aqueduct, in front of the nucleus of the oculomotor nerve. Some are probably derived from the posterior part of the thalamus and from the superior colliculus, whereas others are believed to be continued downward into the medial longitudinal fasciculus. The posterior commissure interconnects the pretectal nuclei, mediating the consensual pupillary light reflex[WP]. Diencephalic tract which is located in the vicinity of the dorsal diencephalon and mesencephalon and connects the pretectal nuclei. From Neuroanatomy of the Zebrafish Brain[ZFA]. go-plus.json commissura posterior|commissura epithalami|caudal commissure|commissura epithalamica|epithalamic commissure|posterior commissure (Lieutaud) http://purl.obolibrary.org/obo/UBERON_0000936 GO:0050222 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050222 GO:0050223 biolink:MolecularActivity protocatechuate decarboxylase activity Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2). RHEA:22416|EC:4.1.1.63|MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN|KEGG_REACTION:R00822 go-plus.json 3,4-dihydrobenzoate decarboxylase activity|3,4-dihydroxybenzoate decarboxylase activity|protocatechuate carboxy-lyase activity|3,4-dihydroxybenzoate carboxy-lyase (catechol-forming) http://purl.obolibrary.org/obo/GO_0050223 GO:0001216 biolink:MolecularActivity DNA-binding transcription activator activity A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets. go-plus.json sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0001216 UBERON:0000930 biolink:AnatomicalEntity stomodeum Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity. go-plus.json oral ectoderm|mouth primordium|stomodeal-hypophyseal primordium|mouth pit|stomatodeum|stomodaeum|primitive oral cavity|oral pit http://purl.obolibrary.org/obo/UBERON_0000930 GO:0050228 biolink:MolecularActivity pterin deaminase activity Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3. EC:3.5.4.11|MetaCyc:PTERIN-DEAMINASE-RXN|RHEA:11904 go-plus.json acrasinase activity|2-amino-4-hydroxypteridine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0050228 NCBITaxon:1035538 biolink:OrganismalEntity Mamiellophyceae go-plus.json prasinophytes http://purl.obolibrary.org/obo/NCBITaxon_1035538 GO:0050229 biolink:MolecularActivity pterocarpin synthase activity Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH. MetaCyc:PTEROCARPIN-SYNTHASE-RXN|RHEA:13533|EC:1.1.1.246 go-plus.json pterocarpan synthase activity|medicarpin:NADP+ 2'-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050229 GO:0001210 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001210 UBERON:0000931 biolink:AnatomicalEntity proctodeum Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract. go-plus.json amnioproctodeal invagination|anus porus|proctodaeum|anal pit|embryonic proctodaeum http://purl.obolibrary.org/obo/UBERON_0000931 GO:0050226 biolink:MolecularActivity psychosine sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate. EC:2.8.2.13|RHEA:14137|MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN go-plus.json psychosine sulphotransferase activity|PAPS:psychosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity|3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity http://purl.obolibrary.org/obo/GO_0050226 GO:0001211 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001211 CHEBI:144315 biolink:ChemicalSubstance 1-radyl-2-acyl-sn-glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_144315 chebi_ph7_3 GO:0001212 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001212 UBERON:0000933 biolink:AnatomicalEntity pharyngeal muscle A muscle that acts on the pharynx[WP, vetted]. go-plus.json muscle of pharynx|branchial muscle|tunica muscularis pharyngis|musculus pharyngis|pharynx muscle|muscle organ of pharynx|branchial muscles|musculi pharyngis|pharynx muscle organ http://purl.obolibrary.org/obo/UBERON_0000933 GO:0050227 biolink:MolecularActivity pteridine oxidase activity Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown. RHEA:12777|EC:1.17.3.1|MetaCyc:PTERIDINE-OXIDASE-RXN go-plus.json 2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating) http://purl.obolibrary.org/obo/GO_0050227 GO:0015858 biolink:BiologicalProcess nucleoside transport The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015858 UBERON:0000939 biolink:AnatomicalEntity imaginal disc one of the parts of a holometabolous insect larva that will become a portion of the outside of the adult insect during the pupal transformation. go-plus.json imaginal disk http://purl.obolibrary.org/obo/UBERON_0000939 GO:0015859 biolink:BiologicalProcess intracellular nucleoside transport The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0015859 GO:0015854 biolink:BiologicalProcess guanine transport The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015854 GO:0015855 biolink:BiologicalProcess pyrimidine nucleobase transport The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json pyrimidine transmembrane transport|pyrimidine base transport|pyrimidine transport|pyrimidine base transmembrane transport http://purl.obolibrary.org/obo/GO_0015855 GO:0015856 biolink:BiologicalProcess cytosine transport The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json cytosine transmembrane transport http://purl.obolibrary.org/obo/GO_0015856 GO:0015857 biolink:BiologicalProcess uracil transport The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015857 GO:0015850 biolink:BiologicalProcess organic hydroxy compound transport The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. go-plus.json organic alcohol transport http://purl.obolibrary.org/obo/GO_0015850 GO:0015851 biolink:BiologicalProcess nucleobase transport The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json nucleobase transmembrane transport http://purl.obolibrary.org/obo/GO_0015851 GO:0015852 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015852 GO:0015853 biolink:BiologicalProcess adenine transport The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json adenine transmembrane transport http://purl.obolibrary.org/obo/GO_0015853 CHEBI:37196 biolink:ChemicalSubstance bismuth molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_37196 GO:0050220 biolink:MolecularActivity prostaglandin-E synthase activity Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2). Reactome:R-HSA-265295|RHEA:12893|KEGG_REACTION:R02265|EC:5.3.99.3|Reactome:R-HSA-2161660|MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN go-plus.json endoperoxide isomerase activity|Prostaglandin-H(2) E-isomerase activity|prostaglandin endoperoxide E isomerase activity|prostaglandin endoperoxide E2 isomerase activity|prostaglandin H-E isomerase activity|PGE2 isomerase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|prostaglandin-H2 E-isomerase activity|PGE isomerase activity|PGH-PGE isomerase activity|prostaglandin R-prostaglandin E isomerase activity http://purl.obolibrary.org/obo/GO_0050220 GO:0001217 biolink:MolecularActivity DNA-binding transcription repressor activity A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets. go-plus.json bacterial-type DNA binding transcription repressor activity|copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding|cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding|bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding|transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0001217 GO:0050221 biolink:MolecularActivity prostaglandin-E2 9-reductase activity Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH. MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN|EC:1.1.1.189|Reactome:R-HSA-2161651|RHEA:24508 go-plus.json 9-keto-prostaglandin E2 reductase activity|PGE2-9-ketoreductase activity|PGE2-9-OR|prostaglandin E2-9-oxoreductase activity|prostaglandin-E2 9-oxoreductase activity|PGE-9-ketoreductase activity|9-keto-prostaglandin E(2) reductase activity|9-ketoprostaglandin reductase activity|PGE2 9-ketoreductase activity|PGE(2) 9-oxoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity|prostaglandin E 9-ketoreductase activity|PGE(2) 9-ketoreductase activity|PGE2 9-oxoreductase activity|prostaglandin-E(2) 9-oxoreductase activity|reductase, 15-hydroxy-9-oxoprostaglandin http://purl.obolibrary.org/obo/GO_0050221 GO:0001218 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001218 GO:0001219 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001219 UBERON:0000923 biolink:AnatomicalEntity germ layer A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. go-plus.json primary germ layer|embryonic germ layer|embryonic tissue|embryonic germ layers|germinal layer http://purl.obolibrary.org/obo/UBERON_0000923 GO:0050235 biolink:MolecularActivity pyridoxal 4-dehydrogenase activity Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH. KEGG_REACTION:R01707|RHEA:21336|MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN|EC:1.1.1.107 go-plus.json pyridoxal dehydrogenase activity|pyridoxal:NAD+ 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050235 GO:0001224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001224 UBERON:0000924 biolink:AnatomicalEntity ectoderm Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. go-plus.json embryonic ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 GO:0050236 biolink:MolecularActivity pyridoxine:NADP 4-dehydrogenase activity Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal. KEGG_REACTION:R01708|EC:1.1.1.65|MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN|RHEA:16129 go-plus.json pyridoxal reductase activity|PL reductase activity|pyridoxol dehydrogenase activity|pyridoxin dehydrogenase activity|pyridoxine dehydrogenase activity|pyridoxine:NADP 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050236 GO:0001225 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001225 GO:0050233 biolink:MolecularActivity pyranose oxidase activity Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2). MetaCyc:PYRANOSE-OXIDASE-RXN|EC:1.1.3.10|KEGG_REACTION:R00302|RHEA:10552 go-plus.json pyranose-2-oxidase activity|pyranose:oxygen 2-oxidoreductase activity|glucose 2-oxidase activity http://purl.obolibrary.org/obo/GO_0050233 UBERON:0000925 biolink:AnatomicalEntity endoderm Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. go-plus.json entoderm http://purl.obolibrary.org/obo/UBERON_0000925 GO:0001226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001226 GO:0001227 biolink:MolecularActivity DNA-binding transcription repressor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II. go-plus.json transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding|transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific|transcriptional repressor activity, metal ion regulated sequence-specific DNA binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription http://purl.obolibrary.org/obo/GO_0001227 GO:0050234 biolink:MolecularActivity pyrazolylalanine synthase activity Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O. MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN|KEGG_REACTION:R02378|RHEA:24512|EC:4.2.1.50 go-plus.json L-serine hydro-lyase (adding pyrazole)|L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]|beta-pyrazolylalaninase activity http://purl.obolibrary.org/obo/GO_0050234 UBERON:0000926 biolink:AnatomicalEntity mesoderm The middle germ layer of the embryo, between the endoderm and ectoderm. go-plus.json mesodermal mantle|embryonic mesoderm|entire mesoderm http://purl.obolibrary.org/obo/UBERON_0000926 GO:0001220 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001220 GO:0050239 biolink:MolecularActivity pyrithiamine deaminase activity Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3. RHEA:14537|EC:3.5.4.20|MetaCyc:PYRITHIAMIN-DEAMINASE-RXN go-plus.json 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity http://purl.obolibrary.org/obo/GO_0050239 GO:0001221 biolink:MolecularActivity transcription coregulator binding Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery. go-plus.json transcription cofactor binding|RNA polymerase II transcription cofactor binding|RNA polymerase II transcription coregulator binding http://purl.obolibrary.org/obo/GO_0001221 UBERON:0000920 biolink:AnatomicalEntity egg chorion A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish [GO]. go-plus.json chorion (egg)|chorion http://purl.obolibrary.org/obo/UBERON_0000920 GO:0050237 biolink:MolecularActivity pyridoxine 4-oxidase activity Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2. EC:1.1.3.12|MetaCyc:PYRIDOXINE-4-OXIDASE-RXN|RHEA:15033 go-plus.json pyridoxin 4-oxidase activity|pyridoxol 4-oxidase activity|pyridoxine:oxygen 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050237 GO:0001222 biolink:MolecularActivity transcription corepressor binding Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery. go-plus.json RNA polymerase II transcription corepressor binding http://purl.obolibrary.org/obo/GO_0001222 GO:0050238 biolink:MolecularActivity pyridoxine 5-dehydrogenase activity Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor. EC:1.1.99.9|MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN|RHEA:14497 go-plus.json pyridoxine:acceptor 5-oxidoreductase activity|pyridoxine 5'-dehydrogenase activity|pyridoxol 5-dehydrogenase activity|pyridoxal-5-dehydrogenase activity|pyridoxin 5-dehydrogenase activity|pyridoxine:(acceptor) 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050238 GO:0001223 biolink:MolecularActivity transcription coactivator binding Binding to a transcription coactivator, a protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery. go-plus.json RNA polymerase II transcription coactivator binding http://purl.obolibrary.org/obo/GO_0001223 UBERON:0000922 biolink:AnatomicalEntity embryo Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. go-plus.json developing organism|developmental tissue|embryonic organism http://purl.obolibrary.org/obo/UBERON_0000922 GO:0015869 biolink:BiologicalProcess protein-DNA complex transport The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json DNA-protein complex transport http://purl.obolibrary.org/obo/GO_0015869 UBERON:0000927 biolink:AnatomicalEntity mesectoderm A double row of cells which are located at the midline from the end of gastrulations. The morphology of these cells is distinct from adjacent ectodermal cells - they are elongated such that one end remains exposed to the outside of the embryo at the mideline while the other end bissects the internalised mesoderm. go-plus.json MesEc http://purl.obolibrary.org/obo/UBERON_0000927 GO:0015865 biolink:BiologicalProcess purine nucleotide transport The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0015865 GO:0015866 biolink:BiologicalProcess ADP transport The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015866 GO:0015867 biolink:BiologicalProcess ATP transport The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015867 GO:0015868 biolink:BiologicalProcess purine ribonucleotide transport The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0015868 GO:0015861 biolink:BiologicalProcess cytidine transport The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015861 GO:0015862 biolink:BiologicalProcess uridine transport The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015862 GO:0015863 biolink:BiologicalProcess xanthosine transport The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015863 GO:0015864 biolink:BiologicalProcess pyrimidine nucleoside transport The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015864 GO:0015860 biolink:BiologicalProcess purine nucleoside transmembrane transport The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar. go-plus.json purine nucleoside membrane transport|purine nucleoside transport http://purl.obolibrary.org/obo/GO_0015860 GO:0001228 biolink:MolecularActivity DNA-binding transcription activator activity, RNA polymerase II-specific A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. go-plus.json RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding|transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, metal ion regulated sequence-specific DNA binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific|transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription http://purl.obolibrary.org/obo/GO_0001228 GO:0050231 biolink:MolecularActivity putrescine carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate. RHEA:21936|KEGG_REACTION:R01399|MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN|EC:2.1.3.6 go-plus.json putrescine synthase activity|putrescine transcarbamylase activity|carbamoyl-phosphate:putrescine carbamoyltransferase activity|PTCase activity http://purl.obolibrary.org/obo/GO_0050231 GO:0050232 biolink:MolecularActivity putrescine oxidase activity Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2. RHEA:18273|MetaCyc:PUTRESCINE-OXIDASE-RXN|EC:1.4.3.10 go-plus.json putrescine:oxygen oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0050232 GO:0050230 biolink:MolecularActivity purine imidazole-ring cyclase activity Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O. MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN|EC:4.3.2.4 go-plus.json DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing) http://purl.obolibrary.org/obo/GO_0050230 GO:0050246 biolink:MolecularActivity questin monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+). EC:1.14.13.43|RHEA:10836|MetaCyc:QUESTIN-MONOOXYGENASE-RXN|KEGG_REACTION:R02417 go-plus.json questin oxygenase activity|questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening) http://purl.obolibrary.org/obo/GO_0050246 UBERON:0000912 biolink:AnatomicalEntity mucus Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000912 GO:0050247 biolink:MolecularActivity raucaffricine beta-glucosidase activity Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine. RHEA:14557|MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN|EC:3.2.1.125|KEGG_REACTION:R03703 go-plus.json raucaffricine b-glucosidase activity|raucaffricine beta-D-glucohydrolase activity|raucaffricine glucosidase activity|raucaffricine beta-D-glucosidase activity http://purl.obolibrary.org/obo/GO_0050247 UBERON:0000913 biolink:AnatomicalEntity interstitial fluid Interstitial fluid is a bodily fluid consisting of a solution which bathes and surrounds the cells of multicellular animals. It is the main component of the extracellular fluid, which also includes plasma and transcellular fluid. go-plus.json intercellular fluid|tissue fluid http://purl.obolibrary.org/obo/UBERON_0000913 GO:0050244 biolink:MolecularActivity pyruvate oxidase (CoA-acetylating) activity Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2). KEGG_REACTION:R00211|EC:1.2.3.6|MetaCyc:PYRUVATE-OXIDASE-COA-ACETYLATING-RXN|RHEA:21912 go-plus.json pyruvate:oxygen 2-oxidoreductase (CoA-acetylating) http://purl.obolibrary.org/obo/GO_0050244 UBERON:0000914 biolink:AnatomicalEntity organismal segment One of the repeated divisions of the whole organism. go-plus.json segment|serial element http://purl.obolibrary.org/obo/UBERON_0000914 GO:0050245 biolink:MolecularActivity quercitrinase activity Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin. KEGG_REACTION:R02436|RHEA:17465|MetaCyc:QUERCITRINASE-RXN|EC:3.2.1.66 go-plus.json quercitrin 3-L-rhamnohydrolase activity http://purl.obolibrary.org/obo/GO_0050245 UBERON:0000915 biolink:AnatomicalEntity thoracic segment of trunk Subdivision of trunk that lies between the head and the abdomen. go-plus.json anterior subdivision of trunk|upper body|upper trunk|thorax http://purl.obolibrary.org/obo/UBERON_0000915 GO:0050248 biolink:MolecularActivity Renilla-luciferin 2-monooxygenase activity Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light. RHEA:14765|MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN|EC:1.13.12.5 go-plus.json luciferase activity|Renilla-type luciferase activity|Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)|aequorin activity|luciferase (Renilla luciferin) http://purl.obolibrary.org/obo/GO_0050248 GO:0050249 biolink:MolecularActivity Renilla-luciferin sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate. KEGG_REACTION:R03138|EC:2.8.2.10|RHEA:20481|MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN go-plus.json Renilla-luciferin sulphotransferase activity|luciferin sulfotransferase activity|3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity|luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)|luciferin sulfokinase activity http://purl.obolibrary.org/obo/GO_0050249 UBERON:0000916 biolink:AnatomicalEntity abdomen The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. go-plus.json adult abdomen|abdominopelvic region|abdominopelvis|belly|celiac region http://purl.obolibrary.org/obo/UBERON_0000916 GO:0015836 biolink:BiologicalProcess lipid-linked peptidoglycan transport The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json lipid-linked murein transport http://purl.obolibrary.org/obo/GO_0015836 GO:0015837 biolink:BiologicalProcess amine transport The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json amine/polyamine transport http://purl.obolibrary.org/obo/GO_0015837 goslim_pir GO:0015838 biolink:BiologicalProcess amino-acid betaine transport The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json betaine transport http://purl.obolibrary.org/obo/GO_0015838 GO:0015839 biolink:BiologicalProcess cadaverine transport The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015839 GO:0015832 biolink:BiologicalProcess obsolete holin OBSOLETE. (Was not defined before being made obsolete). go-plus.json holin http://purl.obolibrary.org/obo/GO_0015832 GO:1902000 biolink:BiologicalProcess homogentisate catabolic process The chemical reactions and pathways resulting in the breakdown of homogentisate. go-plus.json homogentisate degradation|homogentisate breakdown|homogentisate catabolism http://purl.obolibrary.org/obo/GO_1902000 GO:0015833 biolink:BiologicalProcess peptide transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015833 goslim_pir GO:0015834 biolink:BiologicalProcess peptidoglycan-associated peptide transport The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains. go-plus.json muropeptide transport|peptidoglycan peptide transport|murein peptide transport http://purl.obolibrary.org/obo/GO_0015834 GO:0015835 biolink:BiologicalProcess peptidoglycan transport The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json murein transport http://purl.obolibrary.org/obo/GO_0015835 goslim_pir GO:0015830 biolink:BiologicalProcess diaminopimelate transport The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015830 GO:0015831 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015831 CHEBI:37175 biolink:ChemicalSubstance organic hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_37175 GO:0050242 biolink:MolecularActivity pyruvate, phosphate dikinase activity Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate. EC:2.7.9.1|KEGG_REACTION:R00206|RHEA:10756|MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN go-plus.json PPDK|ATP:pyruvate, phosphate phosphotransferase activity|orthophosphate dikinase pyruvate|pyruvate-inorganic phosphate dikinase activity|pyruvate,phosphate dikinase activity|pyruvate-phosphate dikinase activity|pyruvate-phosphate ligase activity|pyruvic-phosphate dikinase activity|pyruvate, Pi dikinase activity|pyruvate-phosphate dikinase (phosphorylating)|pyruvic-phosphate ligase activity|pyruvate,orthophosphate dikinase activity http://purl.obolibrary.org/obo/GO_0050242 GO:0050243 biolink:MolecularActivity pyruvate dehydrogenase (NADP+) activity Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH. EC:1.2.1.51|KEGG_REACTION:R00210|RHEA:17425|MetaCyc:PYRUVATE-DEHYDROGENASE-NADP%2b-RXN go-plus.json pyruvate:NADP+ oxidoreductase activity|pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)|pyruvate:NADP(+) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050243 GO:0050240 biolink:MolecularActivity pyrogallol 1,2-oxygenase activity Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+). KEGG_REACTION:R03246|RHEA:19673|MetaCyc:PYROGALLOL-12-OXYGENASE-RXN|EC:1.13.11.35 go-plus.json pyrogallol 1,2-dioxygenase activity|1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0050240 CHEBI:37176 biolink:ChemicalSubstance mononuclear parent hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_37176 GO:0050241 biolink:MolecularActivity pyrroline-2-carboxylate reductase activity Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+. EC:1.5.1.1|MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN go-plus.json L-proline:NAD(P)+ 2-oxidoreductase activity|delta1-pyrroline-2-carboxylate reductase activity http://purl.obolibrary.org/obo/GO_0050241 GO:0050257 biolink:MolecularActivity riboflavin phosphotransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN. RHEA:20409|KEGG_REACTION:R00550|EC:2.7.1.42|MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN go-plus.json alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity|G-1-P phosphotransferase activity|riboflavine phosphotransferase activity|D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050257 GO:0001202 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001202 GO:0050258 biolink:MolecularActivity riboflavinase activity Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome. MetaCyc:RIBOFLAVINASE-RXN|RHEA:11408|EC:3.5.99.1|KEGG_REACTION:R01732 go-plus.json riboflavin hydrolase activity http://purl.obolibrary.org/obo/GO_0050258 GO:0001203 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001203 OIO:Subset biolink:OntologyClass go-plus.json http://www.geneontology.org/formats/oboInOwl#Subset GO:0050255 biolink:MolecularActivity ribitol 2-dehydrogenase activity Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH. EC:1.1.1.56|KEGG_REACTION:R01895|RHEA:20053|MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN go-plus.json ribitol:NAD+ 2-oxidoreductase activity|ribitol dehydrogenase D (mutant enzyme with different properties)|ribitol dehydrogenase B (mutant enzyme with different properties)|adonitol dehydrogenase activity|ribitol dehydrogenase A (wild type) http://purl.obolibrary.org/obo/GO_0050255 GO:0001204 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001204 GO:0050256 biolink:MolecularActivity ribitol-5-phosphate 2-dehydrogenase activity Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+. EC:1.1.1.137|MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN go-plus.json dehydrogenase, ribitol 5-phosphate|D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050256 CHEBI:168396 biolink:ChemicalSubstance mycophenolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_168396 GO:0001205 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001205 CHEBI:37193 biolink:ChemicalSubstance elemental lead go-plus.json http://purl.obolibrary.org/obo/CHEBI_37193 GO:0050259 biolink:MolecularActivity ribose 1-dehydrogenase (NADP+) activity Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH. RHEA:11676|MetaCyc:RIBOSE-1-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01079|EC:1.1.1.115 go-plus.json NADP-pentose-dehydrogenase activity|D-ribose:NADP+ 1-oxidoreductase activity|D-ribose dehydrogenase (NADP+) http://purl.obolibrary.org/obo/GO_0050259 GO:1902009 biolink:BiologicalProcess positive regulation of toxin transport Any process that activates or increases the frequency, rate or extent of toxin transport. go-plus.json up regulation of toxin transport|activation of toxin transport|up-regulation of toxin transport|upregulation of toxin transport http://purl.obolibrary.org/obo/GO_1902009 CHEBI:37190 biolink:ChemicalSubstance silicon coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_37190 GO:0001200 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001200 GO:0001201 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001201 CHEBI:37191 biolink:ChemicalSubstance silicon oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_37191 GO:1902007 biolink:BiologicalProcess regulation of toxin transport Any process that modulates the frequency, rate or extent of toxin transport. go-plus.json http://purl.obolibrary.org/obo/GO_1902007 GO:1902008 biolink:BiologicalProcess negative regulation of toxin transport Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport. go-plus.json downregulation of toxin transport|down-regulation of toxin transport|inhibition of toxin transport|down regulation of toxin transport http://purl.obolibrary.org/obo/GO_1902008 GO:1902005 biolink:BiologicalProcess regulation of proline biosynthetic process Any process that modulates the frequency, rate or extent of proline biosynthetic process. go-plus.json regulation of proline anabolism|regulation of proline synthesis|regulation of proline formation|regulation of proline biosynthesis http://purl.obolibrary.org/obo/GO_1902005 GO:1902006 biolink:BiologicalProcess negative regulation of proline biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process. go-plus.json inhibition of proline biosynthesis|negative regulation of proline formation|down-regulation of proline formation|inhibition of proline anabolism|inhibition of proline synthesis|negative regulation of proline biosynthesis|down-regulation of proline biosynthesis|down-regulation of proline biosynthetic process|down regulation of proline anabolism|inhibition of proline formation|downregulation of proline anabolism|down regulation of proline synthesis|down regulation of proline formation|downregulation of proline biosynthesis|downregulation of proline biosynthetic process|downregulation of proline synthesis|downregulation of proline formation|down regulation of proline biosynthetic process|down regulation of proline biosynthesis|negative regulation of proline anabolism|down-regulation of proline anabolism|inhibition of proline biosynthetic process|negative regulation of proline synthesis|down-regulation of proline synthesis http://purl.obolibrary.org/obo/GO_1902006 GO:1902003 biolink:BiologicalProcess regulation of amyloid-beta formation Any process that modulates the frequency, rate or extent of amyloid-beta formation. go-plus.json regulation of beta-amyloid formation http://purl.obolibrary.org/obo/GO_1902003 GO:0015847 biolink:BiologicalProcess putrescine transport The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. go-plus.json http://purl.obolibrary.org/obo/GO_0015847 GO:0015848 biolink:BiologicalProcess spermidine transport The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015848 GO:1902004 biolink:BiologicalProcess positive regulation of amyloid-beta formation Any process that activates or increases the frequency, rate or extent of amyloid-beta formation. go-plus.json upregulation of beta-amyloid formation|positive regulation of beta-amyloid formation|up-regulation of beta-amyloid formation|activation of beta-amyloid formation|up regulation of beta-amyloid formation http://purl.obolibrary.org/obo/GO_1902004 GO:0015849 biolink:BiologicalProcess organic acid transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015849 goslim_pir GO:1902001 biolink:BiologicalProcess fatty acid transmembrane transport The process in which a fatty acid is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902001 GO:1902002 biolink:BiologicalProcess obsolete protein phosphorylation involved in cellular protein catabolic process OBSOLETE. Any protein phosphorylation that is involved in cellular protein catabolic process. go-plus.json protein phosphorylation involved in cellular protein catabolism|protein amino acid phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein breakdown|protein amino acid phosphorylation involved in cellular protein catabolism|protein phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein catabolic process|protein phosphorylation involved in cellular protein breakdown http://purl.obolibrary.org/obo/GO_1902002 GO:0015843 biolink:BiologicalProcess methylammonium transport The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015843 GO:1902010 biolink:BiologicalProcess negative regulation of translation in response to endoplasmic reticulum stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. go-plus.json inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein anabolism involved in ER stress response|downregulation of protein biosynthetic process involved in ER stress response|downregulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein anabolism involved in response to ER stress|protein biosynthetic process inhibitor activity involved in ER stress response|protein biosynthesis inhibitor activity involved in ER stress response|down regulation of protein biosynthetic process involved in response to ER stress|inhibition of protein biosynthetic process involved in response to ER stress|negative regulation of protein synthesis involved in response to ER stress|negative regulation of protein formation involved in response to endoplasmic reticulum stress|protein biosynthesis inhibitor activity involved in response to ER stress|protein biosynthetic process inhibitor activity involved in response to ER stress|negative regulation of protein biosynthesis involved in ER stress response|down-regulation of protein biosynthetic process involved in ER stress response|negative regulation of protein biosynthetic process involved in ER stress response|negative regulation of protein formation involved in response to ER stress|negative regulation of protein synthesis involved in response to endoplasmic reticulum stress|down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of translation involved in response to ER stress|negative regulation of protein anabolism involved in response to endoplasmic reticulum stress|downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|inhibition of protein biosynthetic process involved in ER stress response|protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress|protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress|negative regulation of translation involved in ER stress response|negative regulation of protein biosynthetic process involved in response to ER stress|down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress|down-regulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthesis involved in response to ER stress|negative regulation of protein formation involved in ER stress response|negative regulation of protein synthesis involved in ER stress response|down regulation of protein biosynthetic process involved in ER stress response http://purl.obolibrary.org/obo/GO_1902010 GO:1902011 biolink:BiologicalProcess poly(ribitol phosphate) teichoic acid metabolic process The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid. go-plus.json poly(ribitol phosphate) teichoic acid metabolism http://purl.obolibrary.org/obo/GO_1902011 GO:0015844 biolink:BiologicalProcess monoamine transport The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015844 GO:0015845 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015845 GO:0015846 biolink:BiologicalProcess polyamine transport The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015846 GO:0015840 biolink:BiologicalProcess urea transport The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2. go-plus.json http://purl.obolibrary.org/obo/GO_0015840 GO:0015841 biolink:BiologicalProcess chromaffin granule amine transport The directed movement of amines into, out of or within chromaffin granules. go-plus.json http://purl.obolibrary.org/obo/GO_0015841 GO:0015842 biolink:BiologicalProcess aminergic neurotransmitter loading into synaptic vesicle The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps. go-plus.json http://purl.obolibrary.org/obo/GO_0015842 GO:0050250 biolink:MolecularActivity retinal oxidase activity Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2. EC:1.2.3.11|RHEA:22520|MetaCyc:RETINAL-OXIDASE-RXN go-plus.json retinene oxidase activity|retinal:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050250 GO:0050253 biolink:MolecularActivity retinyl-palmitate esterase activity Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+. MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN|RHEA:21508|Reactome:R-HSA-2404133|Reactome:R-HSA-975594|EC:3.1.1.21|Reactome:R-HSA-975593|KEGG_REACTION:R02368|Reactome:R-HSA-8848355 go-plus.json retinyl ester hydrolase activity|retinyl-palmitate palmitohydrolase activity|retinyl palmitate hydrolase activity|retinyl palmitate hydrolyase activity http://purl.obolibrary.org/obo/GO_0050253 GO:0001206 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001206 GO:0050254 biolink:MolecularActivity rhodopsin kinase activity Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin. Reactome:R-HSA-2581474|RHEA:23356|MetaCyc:2.7.11.14-RXN|EC:2.7.11.14 go-plus.json ATP:rhodopsin phosphotransferase activity|cone opsin kinase activity|GRK1|G-protein-coupled receptor kinase 1 activity|STK14|rhodopsin kinase (phosphorylating) activity|opsin kinase activity|GPCR kinase 1 activity|RK|opsin kinase (phosphorylating) activity|GRK7 http://purl.obolibrary.org/obo/GO_0050254 GO:0001207 biolink:BiologicalProcess histone displacement The removal of histones, including histone dimers, from nucleosomes within chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0001207 GO:0001208 biolink:BiologicalProcess histone H2A-H2B dimer displacement The removal of a H2A-H2B histone dimer from a nucleosome within chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0001208 GO:0050251 biolink:MolecularActivity retinol isomerase activity Catalysis of the reaction: all-trans-retinol = 11-cis-retinol. Reactome:R-HSA-2465926|KEGG_REACTION:R02369|RHEA:19141|MetaCyc:RETINOL-ISOMERASE-RXN go-plus.json all-trans-retinol 11-cis-trans-isomerase activity|all-trans-retinol isomerase activity http://purl.obolibrary.org/obo/GO_0050251 GO:0050252 biolink:MolecularActivity retinol O-fatty-acyltransferase activity Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester. Reactome:R-HSA-8848585|Reactome:R-HSA-2465919|EC:2.3.1.76|RHEA:11488|MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN go-plus.json retinol acyltransferase activity|acyl-CoA:retinol O-acyltransferase activity|retinol fatty-acyltransferase activity http://purl.obolibrary.org/obo/GO_0050252 GO:0001209 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001209 GO:1990596 biolink:BiologicalProcess histone H3-K4 deacetylation The modification of histone H3 by the removal of an acetyl group from lysine at position 4 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_1990596 GO:1990597 biolink:CellularComponent AIP1-IRE1 complex A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein). go-plus.json IRE1-DAB2IP complex|AIP1-ERN1 complex|IRE1alpha-AIP1 complex http://purl.obolibrary.org/obo/GO_1990597 GO:1990598 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990598 GO:1990599 biolink:MolecularActivity 3' overhang single-stranded DNA endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks. go-plus.json http://purl.obolibrary.org/obo/GO_1990599 GO:1990592 biolink:BiologicalProcess protein K69-linked ufmylation A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990592 GO:1990593 biolink:MolecularActivity nascent polypeptide-associated complex binding Binding to nascent polypeptide-associated complex, a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome. go-plus.json NACA binding|NAC binding http://purl.obolibrary.org/obo/GO_1990593 GO:1990594 biolink:MolecularActivity L-altrarate dehydratase activity Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O. RHEA:44028 go-plus.json L-talarate dehydratase activity http://purl.obolibrary.org/obo/GO_1990594 GO:1990595 biolink:MolecularActivity mast cell secretagogue receptor activity Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990595 GO:2001039 biolink:BiologicalProcess negative regulation of cellular response to drug Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug. go-plus.json http://purl.obolibrary.org/obo/GO_2001039 GO:1990590 biolink:CellularComponent ATF1-ATF4 transcription factor complex Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1990590 GO:1990591 biolink:BiologicalProcess asparagine transmembrane import into vacuole The directed movement of asparagine into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990591 GO:2001031 biolink:BiologicalProcess positive regulation of cellular glucuronidation Any process that activates or increases the frequency, rate or extent of cellular glucuronidation. go-plus.json positive regulation of cellular glucuronoside biosynthesis|positive regulation of cellular glucuronoside biosynthetic process|positive regulation of cellular glucuronide biosynthetic process|positive regulation of cellular glucuronide biosynthesis http://purl.obolibrary.org/obo/GO_2001031 GO:2001032 biolink:BiologicalProcess regulation of double-strand break repair via nonhomologous end joining Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining. go-plus.json regulation of NHEJ http://purl.obolibrary.org/obo/GO_2001032 GO:2001033 biolink:BiologicalProcess negative regulation of double-strand break repair via nonhomologous end joining Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining. go-plus.json negative regulation of NHEJ http://purl.obolibrary.org/obo/GO_2001033 GO:2001034 biolink:BiologicalProcess positive regulation of double-strand break repair via nonhomologous end joining Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining. go-plus.json positive regulation of NHEJ http://purl.obolibrary.org/obo/GO_2001034 GO:2001035 biolink:BiologicalProcess regulation of tongue muscle cell differentiation Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001035 GO:2001036 biolink:BiologicalProcess negative regulation of tongue muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001036 GO:2001037 biolink:BiologicalProcess positive regulation of tongue muscle cell differentiation Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001037 GO:2001038 biolink:BiologicalProcess regulation of cellular response to drug Any process that modulates the frequency, rate or extent of cellular response to drug. go-plus.json http://purl.obolibrary.org/obo/GO_2001038 CHEBI:76760 biolink:ChemicalSubstance EC 3.1.* (ester hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76760 CHEBI:76761 biolink:ChemicalSubstance EC 3.2.* (glycosylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76761 CHEBI:76764 biolink:ChemicalSubstance EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76764 GO:2001030 biolink:BiologicalProcess negative regulation of cellular glucuronidation Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation. go-plus.json negative regulation of cellular glucuronoside biosynthetic process|negative regulation of cellular glucuronoside biosynthesis|negative regulation of cellular glucuronide biosynthesis|negative regulation of cellular glucuronide biosynthetic process http://purl.obolibrary.org/obo/GO_2001030 CHEBI:76779 biolink:ChemicalSubstance EC 3.4.21.26 (prolyl oligopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76779 CHEBI:27802 biolink:ChemicalSubstance 2,3-dihydroxybenzenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27802 CHEBI:27803 biolink:ChemicalSubstance cis-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27803 CHEBI:76778 biolink:ChemicalSubstance IMP residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_76778 CHEBI:27804 biolink:ChemicalSubstance cyclohexanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27804 chebi_ph7_3 CHEBI:62130 biolink:ChemicalSubstance beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_62130 chebi_ph7_3 GO:2001042 biolink:BiologicalProcess negative regulation of septum digestion after cytokinesis Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. go-plus.json negative regulation of cytokinetic cell separation http://purl.obolibrary.org/obo/GO_2001042 GO:2001043 biolink:BiologicalProcess positive regulation of septum digestion after cytokinesis Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. go-plus.json positive regulation of cell separation after cytokinesis|positive regulation of cytokinetic cell separation http://purl.obolibrary.org/obo/GO_2001043 GO:2001044 biolink:BiologicalProcess regulation of integrin-mediated signaling pathway Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway. go-plus.json regulation of integrin-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2001044 GO:2001045 biolink:BiologicalProcess negative regulation of integrin-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway. go-plus.json negative regulation of integrin-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2001045 GO:2001046 biolink:BiologicalProcess positive regulation of integrin-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway. go-plus.json positive regulation of integrin-mediated signalling pathway http://purl.obolibrary.org/obo/GO_2001046 GO:2001047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001047 GO:2001048 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001048 GO:2001049 biolink:BiologicalProcess regulation of tendon cell differentiation Any process that modulates the frequency, rate or extent of tendon cell differentiation. go-plus.json regulation of tenocyte differentiation|regulation of muscle attachment cell differentiation http://purl.obolibrary.org/obo/GO_2001049 CHEBI:27809 biolink:ChemicalSubstance L-4-hydroxyglutamic semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27809 CHEBI:76770 biolink:ChemicalSubstance EC 3.11.* (hydrolases acting on C-P bonds) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76770 CHEBI:76775 biolink:ChemicalSubstance EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76775 GO:2001040 biolink:BiologicalProcess positive regulation of cellular response to drug Any process that activates or increases the frequency, rate or extent of cellular response to drug. go-plus.json http://purl.obolibrary.org/obo/GO_2001040 CHEBI:76773 biolink:ChemicalSubstance EC 3.1.1.* (carboxylic ester hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76773 GO:2001041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001041 CHEBI:76788 biolink:ChemicalSubstance EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76788 CHEBI:76789 biolink:ChemicalSubstance EC 2.4.1.* (hexosyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76789 CHEBI:62141 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62141 chebi_ph7_3 CHEBI:86110 biolink:ChemicalSubstance O-[S-(6Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86110 chebi_ph7_3 CHEBI:86113 biolink:ChemicalSubstance (25R)-4beta,26-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86113 chebi_ph7_3 CHEBI:86115 biolink:ChemicalSubstance (25R)-3beta,4beta-dihydroxycholest-5-en-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_86115 chebi_ph7_3 GO:2001053 biolink:BiologicalProcess regulation of mesenchymal cell apoptotic process Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. go-plus.json regulation of mesenchymal cell apoptosis http://purl.obolibrary.org/obo/GO_2001053 CHEBI:86116 biolink:ChemicalSubstance (25R)-3beta,4beta-dihydroxycholest-5-en-26-oate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86116 chebi_ph7_3 GO:2001054 biolink:BiologicalProcess negative regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. go-plus.json negative regulation of mesenchymal cell apoptosis http://purl.obolibrary.org/obo/GO_2001054 CL:0000186 biolink:Cell myofibroblast cell An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. go-plus.json MFB http://purl.obolibrary.org/obo/CL_0000186 CL:0000187 biolink:Cell muscle cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. go-plus.json myocyte|muscle fiber http://purl.obolibrary.org/obo/CL_0000187 GO:2001055 biolink:BiologicalProcess positive regulation of mesenchymal cell apoptotic process Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process. go-plus.json positive regulation of mesenchymal cell apoptosis http://purl.obolibrary.org/obo/GO_2001055 CL:0000188 biolink:Cell cell of skeletal muscle A somatic cell located in skeletal muscle. go-plus.json skeletal muscle cell http://purl.obolibrary.org/obo/CL_0000188 GO:2001056 biolink:BiologicalProcess positive regulation of cysteine-type endopeptidase activity Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity. go-plus.json positive regulation of lysosomal cysteine-type endopeptidase|positive regulation of thiol endopeptidase activity http://purl.obolibrary.org/obo/GO_2001056 CHEBI:86119 biolink:ChemicalSubstance 1-hexadecanoyl-2-[(5Z,8Z,11Z)-icosatrienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86119 chebi_ph7_3 GO:2001057 biolink:BiologicalProcess reactive nitrogen species metabolic process The chemical reactions and pathways involving a reactive nitrogen species. go-plus.json RNS metabolic process|RNS metabolism|reactive nitrogen species metabolism http://purl.obolibrary.org/obo/GO_2001057 CL:0000189 biolink:Cell slow muscle cell A muscle cell that develops tension more slowly than a fast-twitch fiber. go-plus.json slow muscle fiber http://purl.obolibrary.org/obo/CL_0000189 GO:2001058 biolink:BiologicalProcess D-tagatose 6-phosphate metabolic process The chemical reactions and pathways involving a D-tagatose 6-phosphate. go-plus.json D-tagatose 6-phosphate metabolism http://purl.obolibrary.org/obo/GO_2001058 GO:2001059 biolink:BiologicalProcess D-tagatose 6-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate. UniPathway:UPA00704 go-plus.json D-tagatose 6-phosphate catabolism http://purl.obolibrary.org/obo/GO_2001059 CHEBI:76782 biolink:ChemicalSubstance EC 3.4.15.* (peptidyl-dipeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76782 CL:0000180 biolink:Cell estradiol secreting cell A steroid hormone secreting cell that secretes estradiol. go-plus.json http://purl.obolibrary.org/obo/CL_0000180 GO:2001050 biolink:BiologicalProcess negative regulation of tendon cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation. go-plus.json negative regulation of tenocyte differentiation|negative regulation of muscle attachment cell differentiation http://purl.obolibrary.org/obo/GO_2001050 CL:0000182 biolink:Cell hepatocyte The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. go-plus.json http://purl.obolibrary.org/obo/CL_0000182 CHEBI:76787 biolink:ChemicalSubstance EC 3.4.11.* (aminopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76787 GO:2001051 biolink:BiologicalProcess positive regulation of tendon cell differentiation Any process that activates or increases the frequency, rate or extent of tendon cell differentiation. go-plus.json positive regulation of tenocyte differentiation|positive regulation of muscle attachment cell differentiation http://purl.obolibrary.org/obo/GO_2001051 CL:0000183 biolink:Cell contractile cell A cell whose primary function is to shorten. go-plus.json http://purl.obolibrary.org/obo/CL_0000183 GO:2001052 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001052 CHEBI:76785 biolink:ChemicalSubstance EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76785 CHEBI:62150 biolink:ChemicalSubstance (3,4-dimethoxyphenyl)methanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62150 chebi_ph7_3 CHEBI:86102 biolink:ChemicalSubstance 1-tetradecanoyl-2-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86102 chebi_ph7_3 GO:2001064 biolink:MolecularActivity cellooligosaccharide binding Binding to cellooligosaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_2001064 CL:0000197 biolink:Cell sensory receptor cell A cell that is capable of detection of a stimulus involved in sensory perception. go-plus.json receptor cell http://purl.obolibrary.org/obo/CL_0000197 GO:2001065 biolink:MolecularActivity mannan binding Binding to mannan. go-plus.json mannoglycan binding http://purl.obolibrary.org/obo/GO_2001065 GO:2001066 biolink:MolecularActivity amylopectin binding Binding to amylopectin. go-plus.json http://purl.obolibrary.org/obo/GO_2001066 CL:0000199 biolink:Cell mechanoreceptor cell A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. go-plus.json mechanoreceptor http://purl.obolibrary.org/obo/CL_0000199 GO:2001067 biolink:MolecularActivity pullulan binding Binding to pullulan. go-plus.json http://purl.obolibrary.org/obo/GO_2001067 GO:2001068 biolink:MolecularActivity arabinoxylan binding Binding to arabinoxylan. go-plus.json http://purl.obolibrary.org/obo/GO_2001068 GO:2001069 biolink:MolecularActivity glycogen binding Binding to glycogen. go-plus.json liver starch binding|animal starch binding http://purl.obolibrary.org/obo/GO_2001069 CHEBI:76790 biolink:ChemicalSubstance EC 2.4.2.* (pentosyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76790 CHEBI:76791 biolink:ChemicalSubstance EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76791 GO:2001060 biolink:BiologicalProcess D-glycero-D-manno-heptose 7-phosphate metabolic process The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate. go-plus.json D-glycero-D-manno-heptose 7-phosphate metabolism http://purl.obolibrary.org/obo/GO_2001060 CL:0000192 biolink:Cell smooth muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). go-plus.json smooth muscle fiber|SMCs|myocytes, smooth muscle|non-striated muscle cell http://purl.obolibrary.org/obo/CL_0000192 CHEBI:76797 biolink:ChemicalSubstance EC 2.5.1.18 (glutathione transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76797 GO:2001061 biolink:BiologicalProcess D-glycero-D-manno-heptose 7-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate. UniPathway:UPA00041 go-plus.json D-glycero-D-manno-heptose 7-phosphate biosynthesis http://purl.obolibrary.org/obo/GO_2001061 GO:2001062 biolink:MolecularActivity xylan binding Binding to xylan. go-plus.json http://purl.obolibrary.org/obo/GO_2001062 CHEBI:76796 biolink:ChemicalSubstance EC 3.4.22.* (cysteine endopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76796 GO:2001063 biolink:MolecularActivity glucomannan binding Binding to glucomannan. go-plus.json http://purl.obolibrary.org/obo/GO_2001063 GO:1990552 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990552 GO:1990553 biolink:BiologicalProcess mitochondrial 5'-adenylyl sulfate transmembrane transport The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990553 GO:1990554 biolink:BiologicalProcess mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990554 GO:1990555 biolink:BiologicalProcess mitochondrial oxaloacetate transmembrane transport The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990555 PR:000014543 biolink:Protein secretin A protein that is a translation product of the human SCT gene or a 1:1 ortholog thereof. go-plus.json SCT http://purl.obolibrary.org/obo/PR_000014543 PR:000014544 biolink:Protein secretin receptor A glucagon-like receptor that is a translation product of the human SCTR gene or a 1:1 ortholog thereof. go-plus.json SCTR|SCT-R http://purl.obolibrary.org/obo/PR_000014544 GO:1990550 biolink:BiologicalProcess mitochondrial alpha-ketoglutarate transmembrane transport The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json mitochondrial 2-oxoglutarate transmembrane transport http://purl.obolibrary.org/obo/GO_1990550 GO:1990551 biolink:BiologicalProcess mitochondrial 2-oxoadipate transmembrane transport The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990551 CHEBI:62164 biolink:ChemicalSubstance N-acetylmannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62164 CHEBI:86131 biolink:ChemicalSubstance 5alpha-cholesta-8,14-dien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86131 chebi_ph7_3 CHEBI:86132 biolink:ChemicalSubstance (9Z,12Z)-hexadeca-9,12,15-trienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86132 CHEBI:86133 biolink:ChemicalSubstance 1-[(9Z)-octadecenoyl]-2-[(9Z,12Z,15Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86133 chebi_ph7_3 CHEBI:86135 biolink:ChemicalSubstance (5Z,9Z,12Z,15Z)-octadecatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86135 CHEBI:86136 biolink:ChemicalSubstance (5Z,9Z,12Z)-octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86136 CHEBI:86137 biolink:ChemicalSubstance 1-hexadecanoyl-2-[(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86137 chebi_ph7_3 CL:0000163 biolink:Cell endocrine cell A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. go-plus.json endocrinocyte http://purl.obolibrary.org/obo/CL_0000163 CL:0000164 biolink:Cell enteroendocrine cell An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. go-plus.json http://purl.obolibrary.org/obo/CL_0000164 CHEBI:86139 biolink:ChemicalSubstance N-methyl-L-alpha-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_86139 chebi_ph7_3 CL:0000165 biolink:Cell neuroendocrine cell An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. go-plus.json neurosecretory cell http://purl.obolibrary.org/obo/CL_0000165 CL:0000166 biolink:Cell chromaffin cell A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. go-plus.json phaeochromocyte http://purl.obolibrary.org/obo/CL_0000166 CL:0000167 biolink:Cell peptide hormone secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000167 CL:0000168 biolink:Cell insulin secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000168 CL:0000169 biolink:Cell type B pancreatic cell A cell that secretes insulin and is located towards the center of the islets of Langerhans. go-plus.json beta cell of pancreatic islet|B-cell of pancreatic islet|pancreatic islet core|pancreatic B-cell|beta cell|type B enteroendocrine cell|beta cell islet|pancreatic B cell|pancreatic beta cell|insulin-secreting cell http://purl.obolibrary.org/obo/CL_0000169 GO:1990556 biolink:BiologicalProcess mitochondrial isopropylmalate transmembrane transport The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990556 GO:1990557 biolink:BiologicalProcess mitochondrial sulfate transmembrane transport The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990557 CL:0000160 biolink:Cell goblet cell A cell of the epithelial lining that produce and secrete mucins. go-plus.json chalice cell http://purl.obolibrary.org/obo/CL_0000160 GO:1990558 biolink:BiologicalProcess mitochondrial malonate(1-) transmembrane transport The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990558 CL:0000161 biolink:Cell acid secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000161 GO:1990559 biolink:BiologicalProcess mitochondrial coenzyme A transmembrane transport The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990559 GO:1990563 biolink:CellularComponent extracellular exosome complex A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome. go-plus.json exosome complex|extracellular vesicular exosome complex http://purl.obolibrary.org/obo/GO_1990563 GO:1990564 biolink:BiologicalProcess protein polyufmylation Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain. go-plus.json http://purl.obolibrary.org/obo/GO_1990564 GO:1990565 biolink:CellularComponent HSP90-CDC37 chaperone complex A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signalling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 creating a positive feedback loop. Complex binding also prevents rapid ubiquitin-dependent proteosomal degradation of target proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990565 GO:1990566 biolink:CellularComponent I(KACh) inward rectifier potassium channel complex An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits. go-plus.json Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex|muscarinic potassium channel complex|GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex http://purl.obolibrary.org/obo/GO_1990566 CHEBI:62170 biolink:ChemicalSubstance N-acyl-D-mannosamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62170 GO:1990560 biolink:MolecularActivity obsolete DNA methyltransferase binding OBSOLETE. Binding to a DNA methyltransferase. go-plus.json DNA methyltransferase binding http://purl.obolibrary.org/obo/GO_1990560 GO:1990561 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion starvation OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of copper ions. go-plus.json http://purl.obolibrary.org/obo/GO_1990561 GO:1990562 biolink:CellularComponent syndecan-syntenin-ALIX complex An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery. go-plus.json exosome complex http://purl.obolibrary.org/obo/GO_1990562 GO:2001006 biolink:BiologicalProcess regulation of cellulose biosynthetic process Any process that modulates the frequency, rate or extent of cellulose biosynthetic process. go-plus.json regulation of cellulose biosynthesis|regulation of cellulose anabolism|regulation of cellulose synthesis|regulation of cellulose formation http://purl.obolibrary.org/obo/GO_2001006 CHEBI:86120 biolink:ChemicalSubstance (11Z)-hexadec-11-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86120 chebi_ph7_3 GO:2001007 biolink:BiologicalProcess negative regulation of cellulose biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process. go-plus.json negative regulation of cellulose synthesis|negative regulation of cellulose formation|negative regulation of cellulose anabolism|negative regulation of cellulose biosynthesis http://purl.obolibrary.org/obo/GO_2001007 GO:2001008 biolink:BiologicalProcess positive regulation of cellulose biosynthetic process Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process. go-plus.json positive regulation of cellulose formation|positive regulation of cellulose biosynthesis|positive regulation of cellulose anabolism|positive regulation of cellulose synthesis http://purl.obolibrary.org/obo/GO_2001008 CHEBI:86121 biolink:ChemicalSubstance 1-hexadecanoyl-2-[(8Z,11Z,14Z)-eicosatrienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86121 chebi_ph7_3 CHEBI:86122 biolink:ChemicalSubstance (10E,12Z)-hexadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86122 chebi_ph7_3 GO:2001009 biolink:BiologicalProcess regulation of plant-type cell wall cellulose biosynthetic process Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process. go-plus.json regulation of cellulose biosynthesis during cell wall biosynthesis|regulation of cell wall cellulose biosynthesis http://purl.obolibrary.org/obo/GO_2001009 CL:0000174 biolink:Cell steroid hormone secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000174 CL:0000175 biolink:Cell luteal cell A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. go-plus.json lutein cell http://purl.obolibrary.org/obo/CL_0000175 CHEBI:86128 biolink:ChemicalSubstance 2-methyl-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_86128 GO:2001000 biolink:BiologicalProcess regulation of xylan catabolic process Any process that modulates the frequency, rate or extent of xylan catabolic process. go-plus.json regulation of xylan degradation|regulation of xylan catabolism|regulation of xylan breakdown http://purl.obolibrary.org/obo/GO_2001000 CL:0000176 biolink:Cell ecdysteroid secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000176 GO:2001001 biolink:BiologicalProcess negative regulation of xylan catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process. go-plus.json negative regulation of xylan breakdown|negative regulation of xylan catabolism|negative regulation of xylan degradation http://purl.obolibrary.org/obo/GO_2001001 CL:0000177 biolink:Cell testosterone secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000177 CL:0000178 biolink:Cell Leydig cell A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. go-plus.json interstitial cell|interstitial cell of Leydig http://purl.obolibrary.org/obo/CL_0000178 GO:2001002 biolink:BiologicalProcess positive regulation of xylan catabolic process Any process that activates or increases the frequency, rate or extent of xylan catabolic process. go-plus.json positive regulation of xylan catabolism|positive regulation of xylan degradation|positive regulation of xylan breakdown http://purl.obolibrary.org/obo/GO_2001002 CL:0000179 biolink:Cell progesterone secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000179 GO:2001003 biolink:BiologicalProcess regulation of pectin catabolic process Any process that modulates the frequency, rate or extent of pectin catabolic process. go-plus.json regulation of pectin catabolism|regulation of pectin degradation|regulation of pectin breakdown http://purl.obolibrary.org/obo/GO_2001003 GO:2001004 biolink:BiologicalProcess negative regulation of pectin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process. go-plus.json negative regulation of pectin degradation|negative regulation of pectin breakdown|negative regulation of pectin catabolism http://purl.obolibrary.org/obo/GO_2001004 GO:2001005 biolink:BiologicalProcess positive regulation of pectin catabolic process Any process that activates or increases the frequency, rate or extent of pectin catabolic process. go-plus.json positive regulation of pectin degradation|positive regulation of pectin catabolism|positive regulation of pectin breakdown http://purl.obolibrary.org/obo/GO_2001005 GO:1990567 biolink:CellularComponent DPS complex A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22. go-plus.json http://purl.obolibrary.org/obo/GO_1990567 CL:0000170 biolink:Cell glucagon secreting cell A cell that secretes glucagon. go-plus.json glucagon-secreting cell http://purl.obolibrary.org/obo/CL_0000170 CL:0000171 biolink:Cell pancreatic A cell A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. go-plus.json alpha cell of islet of Langerhans|pancreatic alpha cell http://purl.obolibrary.org/obo/CL_0000171 GO:1990568 biolink:CellularComponent obsolete MIS18 complex OBSOLETE. A centromere complex assembly protein that is required for the deposition of CENP-A on the centromere. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP) to reach the centromeres. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly. go-plus.json MIS18 complex http://purl.obolibrary.org/obo/GO_1990568 GO:1990569 biolink:BiologicalProcess UDP-N-acetylglucosamine transmembrane transport The process in which UDP-N-acetylglucosamine is transported across a membrane. go-plus.json UDP-N-acetylglucosamine transport http://purl.obolibrary.org/obo/GO_1990569 CL:0000172 biolink:Cell somatostatin secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000172 CL:0000173 biolink:Cell pancreatic D cell A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. go-plus.json delta cell of islet|D-cell of pancreatic islet|delta cell of pancreatic islet|pancreatic D-cell|somatostatin-secreting pancreatic cell|pancreatic delta cell http://purl.obolibrary.org/obo/CL_0000173 GO:1990574 biolink:CellularComponent meiotic spindle astral microtubule Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_1990574 GO:1990575 biolink:BiologicalProcess mitochondrial L-ornithine transmembrane transport The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json mitochondrial ornithine transport|mitochondrial ornithine transmembrane transport http://purl.obolibrary.org/obo/GO_1990575 GO:1990576 biolink:MolecularActivity G protein-coupled glucose receptor activity Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein coupled glucose receptor activity http://purl.obolibrary.org/obo/GO_1990576 GO:1990577 biolink:BiologicalProcess C-terminal protein demethylation The removal of a methyl group from the C-terminal amino acid of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990577 CHEBI:144378 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144378 chebi_ph7_3 GO:1990570 biolink:BiologicalProcess GDP-mannose transmembrane transport The process in which GDP-mannose is transported across a membrane. go-plus.json GDP-mannose transport http://purl.obolibrary.org/obo/GO_1990570 GO:1990571 biolink:BiologicalProcess meiotic centromere clustering The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I. go-plus.json centromere clustering during meiosis|homologous chromosome movement towards spindle pole in meiosis I prometaphase http://purl.obolibrary.org/obo/GO_1990571 GO:1990572 biolink:CellularComponent TERT-RMRP complex A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP). go-plus.json telomerase reverse transcriptase:RMRP RNA complex http://purl.obolibrary.org/obo/GO_1990572 GO:1990573 biolink:BiologicalProcess potassium ion import across plasma membrane The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json potassium ion uptake|potassium import|potassium ion import http://purl.obolibrary.org/obo/GO_1990573 GO:2001017 biolink:BiologicalProcess regulation of retrograde axon cargo transport Any process that modulates the frequency, rate or extent of retrograde axon cargo transport. go-plus.json regulation of retrograde axonal transport http://purl.obolibrary.org/obo/GO_2001017 CL:0000149 biolink:Cell visual pigment cell go-plus.json pigment cell http://purl.obolibrary.org/obo/CL_0000149 GO:2001018 biolink:BiologicalProcess negative regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport. go-plus.json negative regulation of retrograde axonal transport http://purl.obolibrary.org/obo/GO_2001018 GO:2001019 biolink:BiologicalProcess positive regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport. go-plus.json positive regulation of retrograde axonal transport http://purl.obolibrary.org/obo/GO_2001019 CHEBI:144370 biolink:ChemicalSubstance 3-(2-isocyanovinyl)indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_144370 GO:2001010 biolink:BiologicalProcess negative regulation of plant-type cell wall cellulose biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process. go-plus.json negative regulation of cellulose biosynthesis during cell wall biosynthesis|negative regulation of cell wall cellulose biosynthesis http://purl.obolibrary.org/obo/GO_2001010 GO:2001011 biolink:BiologicalProcess positive regulation of plant-type cell wall cellulose biosynthetic process Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process. go-plus.json positive regulation of cellulose biosynthesis during cell wall biosynthesis|positive regulation of cell wall cellulose biosynthesis http://purl.obolibrary.org/obo/GO_2001011 GO:2001012 biolink:BiologicalProcess mesenchymal cell differentiation involved in renal system development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state. go-plus.json mesenchymal cell differentiation involved in urinary system development|mesenchymal cell differentiation involved in urinary tract development http://purl.obolibrary.org/obo/GO_2001012 CL:0000145 biolink:Cell professional antigen presenting cell A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. go-plus.json APC http://purl.obolibrary.org/obo/CL_0000145 GO:2001013 biolink:BiologicalProcess epithelial cell proliferation involved in renal tubule morphogenesis Any epithelial cell proliferation that is involved in renal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2001013 GO:2001014 biolink:BiologicalProcess regulation of skeletal muscle cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001014 CL:0000146 biolink:Cell simple columnar epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000146 GO:2001015 biolink:BiologicalProcess negative regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001015 CL:0000147 biolink:Cell pigment cell A pigment cell is a cell that contains pigment granules. go-plus.json chromatophore|chromatocyte http://purl.obolibrary.org/obo/CL_0000147 GO:2001016 biolink:BiologicalProcess positive regulation of skeletal muscle cell differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001016 CL:0000148 biolink:Cell melanocyte A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. go-plus.json melanophore http://purl.obolibrary.org/obo/CL_0000148 GO:1990578 biolink:CellularComponent perinuclear endoplasmic reticulum membrane The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. go-plus.json perinuclear ER membrane http://purl.obolibrary.org/obo/GO_1990578 GO:1990579 biolink:BiologicalProcess peptidyl-serine trans-autophosphorylation The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer. go-plus.json serine transautophosphorylation|serine autophosphorylation in trans http://purl.obolibrary.org/obo/GO_1990579 GO:1990585 biolink:MolecularActivity hydroxyproline O-arabinosyltransferase activity Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+. go-plus.json HPAT http://purl.obolibrary.org/obo/GO_1990585 GO:1990586 biolink:CellularComponent divisome complex A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990586 GO:1990587 biolink:CellularComponent FtsQBL complex A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ. go-plus.json FtsB-FtsL-FtsQ complex http://purl.obolibrary.org/obo/GO_1990587 GO:1990588 biolink:CellularComponent FtsBL complex A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL. go-plus.json FtsB-FtsL complex http://purl.obolibrary.org/obo/GO_1990588 CHEBI:144368 biolink:ChemicalSubstance 1,2-diacyl-sn-glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_144368 chebi_ph7_3 CHEBI:62192 biolink:ChemicalSubstance plastoquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62192 chebi_ph7_3 GO:1990581 biolink:BiologicalProcess obsolete lysosome lysis OBSOLETE. The rupture of the lysosomal membrane and loss of contents as a result of osmotic change, G-protein-driven disintegration, or unspecified cause. go-plus.json lysosome lysis|lysosomal lysis http://purl.obolibrary.org/obo/GO_1990581 GO:1990582 biolink:MolecularActivity obsolete intracellular membrane-bounded organelle binding OBSOLETE. The temporary binding of a protein or protein complex to the membrane of an intracellular membrane-bounded organelle. go-plus.json intracellular membrane-bounded organelle binding|intracellular membrane-enclosed organelle binding http://purl.obolibrary.org/obo/GO_1990582 CHEBI:62193 biolink:ChemicalSubstance biotin sulfoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62193 GO:1990583 biolink:MolecularActivity phospholipase D activator activity Increases the activity of the enzyme phospholipase D. go-plus.json http://purl.obolibrary.org/obo/GO_1990583 GO:1990584 biolink:CellularComponent cardiac Troponin complex A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction. go-plus.json cTnC:cTnI:cTnT http://purl.obolibrary.org/obo/GO_1990584 CHEBI:62196 biolink:ChemicalSubstance polysaccharide acid oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62196 GO:2001028 biolink:BiologicalProcess positive regulation of endothelial cell chemotaxis Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2001028 CHEBI:86141 biolink:ChemicalSubstance (9Z,12E)-octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86141 GO:2001029 biolink:BiologicalProcess regulation of cellular glucuronidation Any process that modulates the frequency, rate or extent of cellular glucuronidation. go-plus.json regulation of cellular glucuronoside biosynthesis|regulation of cellular glucuronoside biosynthetic process|regulation of cellular glucuronide biosynthesis|regulation of cellular glucuronide biosynthetic process http://purl.obolibrary.org/obo/GO_2001029 CHEBI:62197 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62197 CHEBI:86142 biolink:ChemicalSubstance (9Z,12E)-hexadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86142 CHEBI:86143 biolink:ChemicalSubstance (14Z)-hexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86143 CHEBI:62194 biolink:ChemicalSubstance (S)-carnitinyl-CoA betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62194 GO:1990580 biolink:BiologicalProcess regulation of cytoplasmic translational termination Any process that modulates the frequency, rate or extent of cytoplasmic translational termination. go-plus.json http://purl.obolibrary.org/obo/GO_1990580 CHEBI:86144 biolink:ChemicalSubstance (14E)-hexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86144 CHEBI:86145 biolink:ChemicalSubstance (7alpha,22R)-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86145 chebi_ph7_3 CHEBI:86146 biolink:ChemicalSubstance (24S,25)-epoxy-7alpha-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86146 chebi_ph7_3 CHEBI:62198 biolink:ChemicalSubstance lipid A-core go-plus.json http://purl.obolibrary.org/obo/CHEBI_62198 CHEBI:86147 biolink:ChemicalSubstance (7Z,10Z)-hexadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86147 CHEBI:62199 biolink:ChemicalSubstance galactosyl-(glucosyl)3-(heptosyl)3-(KDO)2-lipid A-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62199 CHEBI:86148 biolink:ChemicalSubstance (8E,10E,12Z)-octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86148 GO:2001020 biolink:BiologicalProcess regulation of response to DNA damage stimulus Any process that modulates the frequency, rate or extent of response to DNA damage stimulus. go-plus.json regulation of DNA damage response|regulation of response to genotoxic stress|regulation of cellular DNA damage response|regulation of cellular response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_2001020 GO:2001021 biolink:BiologicalProcess negative regulation of response to DNA damage stimulus Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus. go-plus.json negative regulation of cellular DNA damage response|negative regulation of DNA damage response|negative regulation of cellular response to DNA damage stimulus|negative regulation of response to genotoxic stress http://purl.obolibrary.org/obo/GO_2001021 CL:0000153 biolink:Cell glycosaminoglycan secreting cell A cell that secretes glycosaminoglycans. go-plus.json hyaluronic acid secreting cell|GAG secreting cell http://purl.obolibrary.org/obo/CL_0000153 GO:2001022 biolink:BiologicalProcess positive regulation of response to DNA damage stimulus Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus. go-plus.json positive regulation of DNA damage response|positive regulation of cellular DNA damage response|positive regulation of cellular response to DNA damage stimulus|positive regulation of response to genotoxic stress http://purl.obolibrary.org/obo/GO_2001022 CL:0000154 biolink:Cell protein secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000154 GO:2001023 biolink:BiologicalProcess regulation of response to drug Any process that modulates the frequency, rate or extent of response to drug. go-plus.json regulation of drug resistance|regulation of drug susceptibility/resistance http://purl.obolibrary.org/obo/GO_2001023 GO:2001024 biolink:BiologicalProcess negative regulation of response to drug Any process that stops, prevents or reduces the frequency, rate or extent of response to drug. go-plus.json negative regulation of drug resistance|negative regulation of drug susceptibility/resistance http://purl.obolibrary.org/obo/GO_2001024 GO:2001025 biolink:BiologicalProcess positive regulation of response to drug Any process that activates or increases the frequency, rate or extent of response to drug. go-plus.json positive regulation of drug resistance|positive regulation of drug susceptibility/resistance http://purl.obolibrary.org/obo/GO_2001025 CL:0000157 biolink:Cell surfactant secreting cell A cell that specializes in secretion of surfactant in the alveoli of the lung. go-plus.json http://purl.obolibrary.org/obo/CL_0000157 GO:2001026 biolink:BiologicalProcess regulation of endothelial cell chemotaxis Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2001026 CL:0000158 biolink:Cell club cell Epithelial progenitor cell of the lung. Club cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Club cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium. go-plus.json Clara cell|bronchiolar non-ciliated cell|club cell of bronchiole http://purl.obolibrary.org/obo/CL_0000158 CL:0000159 biolink:Cell seromucus secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000159 GO:2001027 biolink:BiologicalProcess negative regulation of endothelial cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_2001027 GO:1990589 biolink:CellularComponent ATF4-CREB1 transcription factor complex Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1990589 CL:0000150 biolink:Cell glandular epithelial cell A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. go-plus.json http://purl.obolibrary.org/obo/CL_0000150 CL:0000151 biolink:Cell secretory cell A cell that specializes in controlled release of one or more substances. go-plus.json http://purl.obolibrary.org/obo/CL_0000151 CHEBI:27757 biolink:ChemicalSubstance 4-chlorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_27757 chebi_ph7_3 GO:1990510 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990510 GO:1990511 biolink:BiologicalProcess piRNA biosynthetic process The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. go-plus.json Piwi-associated RNA biosynthetic process http://purl.obolibrary.org/obo/GO_1990511 UBERON:0010380 biolink:AnatomicalEntity enteric nerve the neurons that innervate the esophagus, stomach, small and large bowel go-plus.json http://purl.obolibrary.org/obo/UBERON_0010380 CHEBI:27754 biolink:ChemicalSubstance methacrylyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27754 CHEBI:27750 biolink:ChemicalSubstance ethyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27750 chebi_ph7_3 UBERON:0010388 biolink:AnatomicalEntity proximal segment of rib The segment of the rib that connects to a vertebra[MP]. a small part of the rib composed of the head, neck, tuberculum and a short proximal part of the body[PMID] go-plus.json proximal part of rib|proximal rib|costal part of rib|vertebral part of rib|proximal rib segment http://purl.obolibrary.org/obo/UBERON_0010388 UBERON:0010389 biolink:AnatomicalEntity pterygoid bone A bone which corresponds to the inner plate of the pterygoid process of the human skull, but which, in all vertebrates below mammals, is not connected with the posterior nares, but serves to connect the palatine bones with the point of suspension of the lower jaw go-plus.json lamina lateralis (processus pterygoideus)|lamina lateralis processi pterygoideus ossis sphenoidalis|lateral plate of sphenoid|lateral plate of pterygoid process|lateral lamina of pterygoid process|inner plate of pterygoid process|pterygoid|lateral pterygoid plate http://purl.obolibrary.org/obo/UBERON_0010389 UBERON:0010386 biolink:AnatomicalEntity Peyer's patch follicle A lymphoid follicle that is part of a Peyer's patch. go-plus.json peyer's patch follicle http://purl.obolibrary.org/obo/UBERON_0010386 UBERON:0010387 biolink:AnatomicalEntity Peyer's patch T cell area The Peyer's patch area normally occupied by T lymphocytes go-plus.json http://purl.obolibrary.org/obo/UBERON_0010387 GO:1990516 biolink:BiologicalProcess ribonucleotide excision repair The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase. go-plus.json http://purl.obolibrary.org/obo/GO_1990516 GO:1990517 biolink:BiologicalProcess obsolete protein localization to photoreceptor outer segment OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment, which is a portion of a modified sensory cilium. go-plus.json http://purl.obolibrary.org/obo/GO_1990517 GO:1990518 biolink:MolecularActivity single-stranded 3'-5' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'. go-plus.json http://purl.obolibrary.org/obo/GO_1990518 GO:1990519 biolink:BiologicalProcess pyrimidine nucleotide import into mitochondrion The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix. go-plus.json mitochondrial pyrimidine nucleotide import http://purl.obolibrary.org/obo/GO_1990519 GO:1990512 biolink:CellularComponent Cry-Per complex Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms. go-plus.json http://purl.obolibrary.org/obo/GO_1990512 GO:1990513 biolink:CellularComponent CLOCK-BMAL transcription complex Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms. go-plus.json CLOCK/BMAL complex http://purl.obolibrary.org/obo/GO_1990513 GO:1990514 biolink:BiologicalProcess 5' transitive RNA interference An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990514 GO:1990515 biolink:BiologicalProcess 3' transitive RNA interference An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990515 GO:1990520 biolink:CellularComponent separase-securin complex A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC). go-plus.json Cut1-2 complex http://purl.obolibrary.org/obo/GO_1990520 GO:1990521 biolink:MolecularActivity m7G(5')pppN diphosphatase activator activity Binds to and increases the activity of m7G(5')pppN diphosphatase. go-plus.json http://purl.obolibrary.org/obo/GO_1990521 GO:1990522 biolink:BiologicalProcess tail spike morphogenesis The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death. WBbt:0008072|WBbt:0006979 go-plus.json http://purl.obolibrary.org/obo/GO_1990522 CHEBI:27765 biolink:ChemicalSubstance (S)-3-hydroxy-3-methyl-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27765 chebi_ph7_3 CHEBI:27767 biolink:ChemicalSubstance 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27767 CHEBI:27760 biolink:ChemicalSubstance L-selenocystathionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27760 CHEBI:27761 biolink:ChemicalSubstance (S)-prunasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27761 chebi_ph7_3 UBERON:0010371 biolink:AnatomicalEntity ecto-epithelium Epithelium composed of cells that develops from the ectoderm[FMA,modified]. go-plus.json ectoderm-derived epithelium http://purl.obolibrary.org/obo/UBERON_0010371 CHEBI:27762 biolink:ChemicalSubstance 3-hydroxypropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27762 UBERON:0010377 biolink:AnatomicalEntity mesenchyme from somatopleure Mesenchyme that develops_from a somatopleure. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010377 UBERON:0010378 biolink:AnatomicalEntity mesenchyme from splanchnopleure Mesenchyme that develops_from a splanchnopleure. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010378 UBERON:0010375 biolink:AnatomicalEntity pancreas dorsal primordium go-plus.json dorsal pancreas http://purl.obolibrary.org/obo/UBERON_0010375 UBERON:0010376 biolink:AnatomicalEntity pancreas ventral primordium go-plus.json ventral pancreas http://purl.obolibrary.org/obo/UBERON_0010376 UBERON:0010368 biolink:AnatomicalEntity pulmonary lobule The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa. go-plus.json lobulus pulmonis http://purl.obolibrary.org/obo/UBERON_0010368 GO:1990527 biolink:CellularComponent Tec1p-Ste12p-Dig1p complex A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_1990527 GO:1990528 biolink:CellularComponent Rvs161p-Rvs167p complex A protein complex that is involved in endocytosis in the yeast S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_1990528 GO:1990529 biolink:CellularComponent glycosylphosphatidylinositol-mannosyltransferase I complex A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M. go-plus.json GPI-MT-I complex http://purl.obolibrary.org/obo/GO_1990529 GO:1990523 biolink:BiologicalProcess bone regeneration The regrowth of bone following its loss or destruction. go-plus.json http://purl.obolibrary.org/obo/GO_1990523 GO:1990524 biolink:CellularComponent INA complex A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p. go-plus.json INAC http://purl.obolibrary.org/obo/GO_1990524 GO:1990525 biolink:MolecularActivity BIR domain binding Binding to a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain. go-plus.json Baculovirus Inhibitor of apoptosis protein Repeat domain binding http://purl.obolibrary.org/obo/GO_1990525 GO:1990526 biolink:CellularComponent Ste12p-Dig1p-Dig2p complex A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_1990526 GO:1990530 biolink:CellularComponent Cdc50p-Drs2p complex A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome. go-plus.json http://purl.obolibrary.org/obo/GO_1990530 CHEBI:27735 biolink:ChemicalSubstance 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27735 GO:1990531 biolink:CellularComponent phospholipid-translocating ATPase complex A protein complex that functions as a phospholipid-translocating P-Type ATPase. go-plus.json Lem3p-Dnf1p complex|CDC50-DRS2 complex|DRS2-CDC50 complex|P4-ATPase complex|phospholipid flippase complex|Dnf1-Lem3 complex|Dnf2-Lem3 complex|APLT complex|DNF3-CRF1 complex|CRF1-DNF3 complex|aminophospholipid translocase complex|Lem3-Dnf1 complex http://purl.obolibrary.org/obo/GO_1990531 GO:1990532 biolink:BiologicalProcess stress response to nickel ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus. go-plus.json response to nickel toxicity|response to nickel ion stress|stress response to nickel http://purl.obolibrary.org/obo/GO_1990532 GO:1990533 biolink:CellularComponent Dom34-Hbs1 complex A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay. go-plus.json Dom34:Hbs1 complex http://purl.obolibrary.org/obo/GO_1990533 CHEBI:27731 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27731 chebi_ph7_3 CHEBI:76706 biolink:ChemicalSubstance EC 6.1.* (C-O bond-forming ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76706 CHEBI:27732 biolink:ChemicalSubstance caffeine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27732 chebi_ph7_3 UBERON:0010362 biolink:AnatomicalEntity endoskeleton Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues. go-plus.json replacement skeleton http://purl.obolibrary.org/obo/UBERON_0010362 UBERON:0010363 biolink:AnatomicalEntity endochondral element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. go-plus.json endochondral replacement element http://purl.obolibrary.org/obo/UBERON_0010363 UBERON:0010360 biolink:AnatomicalEntity pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme. go-plus.json branchial arch mesenchyme from head mesenchyme|arch mesenchyme from head mesenchyme|head mesenchyme derived arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 CHEBI:76709 biolink:ChemicalSubstance 3-hydroxyicosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76709 chebi_ph7_3 CHEBI:27730 biolink:ChemicalSubstance D-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27730 UBERON:0010366 biolink:AnatomicalEntity conjunctival vasculature A vasculature that is part of a conjunctiva. go-plus.json conjunctival veins set|conjunctival veins|venae conjunctivales|set of conjunctival veins http://purl.obolibrary.org/obo/UBERON_0010366 UBERON:0010367 biolink:AnatomicalEntity conjunctival vein A vein that is part of a conjunctiva. go-plus.json conjunctival blood vessel http://purl.obolibrary.org/obo/UBERON_0010367 UBERON:0010364 biolink:AnatomicalEntity dermal skeleton Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements. go-plus.json exoskeleton|desmoskeleton|dermoskeleton|dermal skeletal system http://purl.obolibrary.org/obo/UBERON_0010364 UBERON:0010365 biolink:AnatomicalEntity odontoid tissue Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla. go-plus.json dental tissue|odontogenic tissue|portion of substance of tooth|tooth hard tissue|tooth substance|tooth tissue|substance of tooth http://purl.obolibrary.org/obo/UBERON_0010365 UBERON:0010359 biolink:AnatomicalEntity pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme. go-plus.json neural crest derived arch mesenchyme|arch mesenchyme from neural crest|branchial arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 UBERON:0010358 biolink:AnatomicalEntity arch of centrum of vertebra An arch-shaped structure of the vertebra that extends dorsally (neural arch) or ventrally (hemal arch) from the vertebral centrum go-plus.json arch of vertebra|vertebra arch|arcus vertebrae (vertebralis)|vertebral arch http://purl.obolibrary.org/obo/UBERON_0010358 GO:1990538 biolink:MolecularActivity xylan O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan. go-plus.json http://purl.obolibrary.org/obo/GO_1990538 GO:1990539 biolink:BiologicalProcess fructose import across plasma membrane The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1990539 GO:1990534 biolink:MolecularActivity thermospermine oxidase activity Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine. go-plus.json http://purl.obolibrary.org/obo/GO_1990534 GO:1990535 biolink:BiologicalProcess neuron projection maintenance The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. go-plus.json neuron process maintenance|axon maintenance|neuron protrusion maintenance|neurite maintenance|axon homeostasis|neuronal cell projection maintenance http://purl.obolibrary.org/obo/GO_1990535 GO:1990536 biolink:BiologicalProcess phosphoenolpyruvate transmembrane import into Golgi lumen The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990536 GO:1990537 biolink:CellularComponent mitotic spindle polar microtubule Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone. go-plus.json http://purl.obolibrary.org/obo/GO_1990537 CHEBI:76713 biolink:ChemicalSubstance EC 4.3.* (C-N lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76713 GO:1990541 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990541 GO:1990542 biolink:BiologicalProcess mitochondrial transmembrane transport The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990542 CHEBI:76714 biolink:ChemicalSubstance EC 4.4.* (C-S lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76714 GO:1990543 biolink:BiologicalProcess mitochondrial S-adenosyl-L-methionine transmembrane transport The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990543 CHEBI:27748 biolink:ChemicalSubstance D-ribosylnicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27748 CHEBI:76711 biolink:ChemicalSubstance EC 4.1.* (C-C lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76711 CHEBI:76712 biolink:ChemicalSubstance EC 4.2.* (C-O lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76712 GO:1990544 biolink:BiologicalProcess mitochondrial ATP transmembrane transport The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990544 CHEBI:27742 biolink:ChemicalSubstance gibberellin A20 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27742 CHEBI:27744 biolink:ChemicalSubstance glyphosate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27744 GO:1990540 biolink:BiologicalProcess mitochondrial manganese ion transmembrane transport The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990540 CHEBI:27740 biolink:ChemicalSubstance gamma-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27740 chebi_ph7_3 CHEBI:27741 biolink:ChemicalSubstance 3'-hydroxyflavonoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27741 chebi_ph7_3 UBERON:0010355 biolink:AnatomicalEntity ossification center The first step in ossification of the cartilage is that the cartilage cells, at the point where ossification is commencing and which is termed a ossification center, enlarge and arrange themselves in rows. The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other. A deposit of calcareous material now takes place in this matrix, between the rows of cells, so that they become separated from each other by longitudinal columns of calcified matrix, presenting a granular and opaque appearance. Here and there the matrix between two cells of the same row also becomes calcified, and transverse bars of calcified substance stretch across from one calcareous column to another. Thus there are longitudinal groups of the cartilage cells enclosed in oblong cavities, the walls of which are formed of calcified matrix which cuts off all nutrition from the cells; the cells, in consequence, atrophy, leaving spaces called the primary areolC&. go-plus.json centrum ossificationis|centrum ossificationis|ossification centre|center of ossification http://purl.obolibrary.org/obo/UBERON_0010355 UBERON:0010349 biolink:AnatomicalEntity otic capsule pre-cartilage condensation A otic capsule endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json otic capsule anlage http://purl.obolibrary.org/obo/UBERON_0010349 UBERON:0010347 biolink:AnatomicalEntity 6th arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. go-plus.json pharyngeal arch 6 mesenchyme from head mesenchyme|head mesenchyme derived arch 6 mesenchyme|branchial arch 6 mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010347 CHEBI:13115 biolink:ChemicalSubstance L-gulonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13115 chebi_ph7_3 GO:1990549 biolink:BiologicalProcess mitochondrial NAD transmembrane transport The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990549 GO:1990545 biolink:BiologicalProcess mitochondrial thiamine pyrophosphate transmembrane transport The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990545 GO:1990546 biolink:BiologicalProcess mitochondrial tricarboxylic acid transmembrane transport The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990546 CHEBI:76710 biolink:ChemicalSubstance EC 4.* (lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76710 OIO:hasAlternativeId biolink:OntologyClass has_alternative_id go-plus.json http://www.geneontology.org/formats/oboInOwl#hasAlternativeId GO:1990547 biolink:BiologicalProcess mitochondrial phosphate ion transmembrane transport The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990547 GO:1990548 biolink:BiologicalProcess mitochondrial FAD transmembrane transport The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_1990548 CHEBI:27713 biolink:ChemicalSubstance (5S)-5-amino-3-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27713 CHEBI:76724 biolink:ChemicalSubstance 2-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76724 chebi_ph7_3 CHEBI:76725 biolink:ChemicalSubstance EC 1.* (oxidoreductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76725 CHEBI:27714 biolink:ChemicalSubstance 6-acetyl-2-amino-3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_27714 chebi_ph7_3 CHEBI:27715 biolink:ChemicalSubstance 3-chlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27715 chebi_ph7_3 CHEBI:76722 biolink:ChemicalSubstance 2-hydroxybehenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76722 chebi_ph7_3 CHEBI:76723 biolink:ChemicalSubstance 2-hydroxytetracosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76723 chebi_ph7_3 CHEBI:76728 biolink:ChemicalSubstance 2-hydroxyhexacosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76728 chebi_ph7_3 CHEBI:76729 biolink:ChemicalSubstance EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76729 CHEBI:27711 biolink:ChemicalSubstance precorrin-3B go-plus.json http://purl.obolibrary.org/obo/CHEBI_27711 CHEBI:76726 biolink:ChemicalSubstance EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76726 CHEBI:76727 biolink:ChemicalSubstance EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76727 CHEBI:27717 biolink:ChemicalSubstance gibberellin A1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27717 CHEBI:76735 biolink:ChemicalSubstance EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76735 CHEBI:76736 biolink:ChemicalSubstance EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76736 CHEBI:76733 biolink:ChemicalSubstance EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76733 CHEBI:27726 biolink:ChemicalSubstance 6-chloro-1,3,5-triazine-2,4-diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27726 chebi_ph7_3 CHEBI:27727 biolink:ChemicalSubstance androstane-3,17-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27727 chebi_ph7_3 CHEBI:27721 biolink:ChemicalSubstance trans-tetradec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27721 CHEBI:76737 biolink:ChemicalSubstance EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76737 CHEBI:76738 biolink:ChemicalSubstance EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76738 NCBITaxon:183710 biolink:OrganismalEntity Deinococcaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_183710 CHEBI:76731 biolink:ChemicalSubstance EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76731 CHEBI:76732 biolink:ChemicalSubstance 2-hydroxyarachidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76732 chebi_ph7_3 CHEBI:76730 biolink:ChemicalSubstance EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76730 CHEBI:76744 biolink:ChemicalSubstance EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76744 CHEBI:76748 biolink:ChemicalSubstance EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76748 CHEBI:76740 biolink:ChemicalSubstance EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76740 CHEBI:76741 biolink:ChemicalSubstance EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76741 CHEBI:27702 biolink:ChemicalSubstance (R)-norlaudanosoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_27702 CHEBI:27705 biolink:ChemicalSubstance delta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27705 chebi_ph7_3 GO:1990500 biolink:CellularComponent eif4e-cup complex A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo. go-plus.json eukaryotic translation initiation factor 4E-cup complex http://purl.obolibrary.org/obo/GO_1990500 UBERON:0010392 biolink:AnatomicalEntity B cell domain go-plus.json http://purl.obolibrary.org/obo/UBERON_0010392 CHEBI:76759 biolink:ChemicalSubstance EC 3.* (hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76759 CHEBI:27700 biolink:ChemicalSubstance trans-3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27700 UBERON:0010390 biolink:AnatomicalEntity lumen of urethra An organ cavity that is part of a urethra. go-plus.json urethral lumen http://purl.obolibrary.org/obo/UBERON_0010390 CHEBI:27701 biolink:ChemicalSubstance oxytetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_27701 UBERON:0010395 biolink:AnatomicalEntity lymph node primary follicle An unstimulated network of follicular dendritic cells and small resting B cells in the lymph node cortex. go-plus.json primary follicle of lymph node http://purl.obolibrary.org/obo/UBERON_0010395 UBERON:0010393 biolink:AnatomicalEntity T cell domain go-plus.json http://purl.obolibrary.org/obo/UBERON_0010393 UBERON:0010394 biolink:AnatomicalEntity lymphocyte domain go-plus.json http://purl.obolibrary.org/obo/UBERON_0010394 UBERON:0010399 biolink:AnatomicalEntity spleen trabecular artery one of the branches of the splenic artery[MP] go-plus.json trabecular artery http://purl.obolibrary.org/obo/UBERON_0010399 CHEBI:62111 biolink:ChemicalSubstance 6-O-acetyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62111 chebi_ph7_3 CHEBI:62117 biolink:ChemicalSubstance 6beta-hydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_62117 chebi_ph7_3 GO:1990509 biolink:CellularComponent PYM-mago-Y14 complex Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans. go-plus.json wibg-mago-tsu complex|PYM-mago-RNA-binding protein 8A complex http://purl.obolibrary.org/obo/GO_1990509 GO:1990505 biolink:BiologicalProcess mitotic DNA replication maintenance of fidelity Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication. go-plus.json mitotic DNA replication maintenance of fidelity|maintenance of fidelity involved in mitotic DNA replication|maintenance of fidelity involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1990505 GO:1990506 biolink:BiologicalProcess mitotic DNA-dependent DNA replication A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1990506 GO:1990507 biolink:BiologicalProcess obsolete ATP-independent chaperone mediated protein folding OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_1990507 GO:1990508 biolink:CellularComponent CKM complex Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8. go-plus.json SRB8-SRB11 complex|CDK8 kinase module|SRB8/9/10/11 complex http://purl.obolibrary.org/obo/GO_1990508 GO:1990501 biolink:CellularComponent exon-exon junction subcomplex mago-y14 Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA. go-plus.json MGN-RBM8A complex|mago-y14 complex|exon junction subcomplex MAGOH-Y14 http://purl.obolibrary.org/obo/GO_1990501 CHEBI:27707 biolink:ChemicalSubstance beta-D-Galp-(1->3)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_27707 chebi_ph7_3 GO:1990502 biolink:BiologicalProcess dense core granule maturation Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis. go-plus.json dense core vesicle maturation http://purl.obolibrary.org/obo/GO_1990502 GO:1990503 biolink:CellularComponent dendritic lamellar body A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions. go-plus.json DLB http://purl.obolibrary.org/obo/GO_1990503 CHEBI:27708 biolink:ChemicalSubstance diethyl hydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27708 GO:1990504 biolink:BiologicalProcess dense core granule exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels. go-plus.json dense core vesicle exocytosis http://purl.obolibrary.org/obo/GO_1990504 GO:0001411 biolink:CellularComponent hyphal tip The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0001411 goslim_candida GO:0050389 biolink:MolecularActivity uronolactonase activity Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate. EC:3.1.1.19|RHEA:13337|MetaCyc:URONOLACTONASE-RXN go-plus.json glucuronolactonase activity|D-glucurono-6,2-lactone lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0050389 UBERON:0000978 biolink:AnatomicalEntity leg The portion of the hindlimb that contains both the stylopod and zeugopod. go-plus.json lower extremity|tetrapod leg http://purl.obolibrary.org/obo/UBERON_0000978 UBERON:0000979 biolink:AnatomicalEntity tibia The major preaxial endochondral bone in the posterior zeugopod[Phenoscape]. go-plus.json shinbone|shankbone http://purl.obolibrary.org/obo/UBERON_0000979 GO:0050387 biolink:MolecularActivity urethanase activity Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+). MetaCyc:URETHANASE-RXN|KEGG_REACTION:R02359|EC:3.5.1.75|RHEA:21372 go-plus.json urethane hydrolase activity|urethane amidohydrolase (decarboxylating) http://purl.obolibrary.org/obo/GO_0050387 GO:0050388 biolink:MolecularActivity uronate dehydrogenase activity Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH. RHEA:22404|KEGG_REACTION:R01981|MetaCyc:URONATE-DEHYDROGENASE-RXN|EC:1.1.1.203 go-plus.json uronate: NAD-oxidoreductase activity|uronate:NAD+ 1-oxidoreductase activity|uronic acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050388 UBERON:0000974 biolink:AnatomicalEntity neck An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column. go-plus.json neck (volume)|collum http://purl.obolibrary.org/obo/UBERON_0000974 UBERON:0000975 biolink:AnatomicalEntity sternum A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad]. go-plus.json breastbone|vertebrate sternum http://purl.obolibrary.org/obo/UBERON_0000975 UBERON:0000976 biolink:AnatomicalEntity humerus Paired endochondral long bone that extends between the pectoral girdle and the skeletal parts of the forelimb. [PHENOSCAPE:mah] go-plus.json humeri|humerus bone|proximal metapterygial mesomere of pectoral fin|proximal metapterygial mesomere of pectoral appendage|mesomere 1 of pectoral appendage http://purl.obolibrary.org/obo/UBERON_0000976 UBERON:0000977 biolink:AnatomicalEntity pleura The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion). go-plus.json pleura|wall of pleural sac|pleural tissue http://purl.obolibrary.org/obo/UBERON_0000977 GO:0001410 biolink:BiologicalProcess chlamydospore formation The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans. go-plus.json chlamydospore development http://purl.obolibrary.org/obo/GO_0001410 CHEBI:37158 biolink:ChemicalSubstance bromocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37158 UBERON:0000981 biolink:AnatomicalEntity femur Endochondral longbone connecting the pelvic girdle with posterior zeugopodium skeleton.[VSAO, modified]. go-plus.json os longissimum|femoral bone|os femorale|mesomere 1 of pevlic appendage|proximal metapterygial mesomere of pelvic fin|os femoris|proximal metapterygial mesomere of pelvic appendage|thigh bone http://purl.obolibrary.org/obo/UBERON_0000981 GO:0050381 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050381 UBERON:0000982 biolink:AnatomicalEntity skeletal joint Anatomical cluster that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. go-plus.json articular joint|joints|joint|articulation http://purl.obolibrary.org/obo/UBERON_0000982 CHEBI:52794 biolink:ChemicalSubstance beta-L-aspartylhydroxamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52794 CHEBI:37153 biolink:ChemicalSubstance EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_37153 GO:0050382 biolink:MolecularActivity uracil-5-carboxylate decarboxylase activity Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil. EC:4.1.1.66|KEGG_REACTION:R00973|MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN|RHEA:17685 go-plus.json uracil-5-carboxylic acid decarboxylase activity|uracil-5-carboxylate carboxy-lyase activity|uracil-5-carboxylate carboxy-lyase (uracil-forming) http://purl.obolibrary.org/obo/GO_0050382 UBERON:0000983 biolink:AnatomicalEntity metatarsus region A metapodium region that is part of a pes. go-plus.json hindlimb equine cannon region|hind metapodium|hindlimb cannon region|metatarsal region|regio metatarsalis|metatarsus|metatarsal part of foot http://purl.obolibrary.org/obo/UBERON_0000983 CHEBI:37151 biolink:ChemicalSubstance 1,3-dibromobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37151 chebi_ph7_3 UBERON:0000984 biolink:AnatomicalEntity imaginal disc-derived wing A flight organ of the adult external thorax that is derived from a dorsal mesothoracic disc. go-plus.json adult metathoracic wing|wing|wing of thorax|adult mesothoracic wing|thorax wing|thoracic wing http://purl.obolibrary.org/obo/UBERON_0000984 GO:0050380 biolink:MolecularActivity undecaprenyl-diphosphatase activity Catalysis of the reaction: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate. KEGG_REACTION:R05627|RHEA:28094|MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN|EC:3.6.1.27 go-plus.json undecaprenyl-diphosphate phosphohydrolase activity|C55-isoprenyl pyrophosphatase activity|C55-isoprenyl diphosphatase activity|C(55)-isoprenyl pyrophosphatase activity|C(55)-isoprenyl diphosphatase activity|isoprenyl pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0050380 GO:0050385 biolink:MolecularActivity ureidoglycolate lyase activity Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea. MetaCyc:UREIDOGLYCOLATE-LYASE-RXN|KEGG_REACTION:R00776|RHEA:11304|EC:4.3.2.3 go-plus.json ureidoglycolase activity|(S)-ureidoglycolate urea-lyase activity|ureidoglycolatase activity|(S)-ureidoglycolate urea-lyase (glyoxylate-forming)|ureidoglycolate hydrolase activity http://purl.obolibrary.org/obo/GO_0050385 CHEBI:37156 biolink:ChemicalSubstance maleate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37156 CHEBI:37157 biolink:ChemicalSubstance 3-oxodecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37157 GO:0050386 biolink:MolecularActivity ureidosuccinase activity Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+). EC:3.5.1.7|KEGG_REACTION:R00484|MetaCyc:UREIDOSUCCINASE-RXN|RHEA:14365 go-plus.json N-carbamoyl-L-aspartate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050386 GO:0050383 biolink:MolecularActivity uracil dehydrogenase activity Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor. EC:1.17.99.4|MetaCyc:URACIL-DEHYDROGENASE-RXN|RHEA:22752 go-plus.json http://purl.obolibrary.org/obo/GO_0050383 CHEBI:37154 biolink:ChemicalSubstance fumarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37154 GO:0050384 biolink:MolecularActivity urate-ribonucleotide phosphorylase activity Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate. RHEA:13909|MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN|EC:2.4.2.16|KEGG_REACTION:R02646 go-plus.json urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity|UAR phosphorylase activity|urate-ribonucleotide:phosphate D-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0050384 CHEBI:37155 biolink:ChemicalSubstance hydrogen butenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37155 GO:0050398 biolink:MolecularActivity wax-ester hydrolase activity Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate. RHEA:13577|MetaCyc:WAX-ESTER-HYDROLASE-RXN|EC:3.1.1.50 go-plus.json WEH|wax-ester acylhydrolase activity|jojoba wax esterase http://purl.obolibrary.org/obo/GO_0050398 GO:0050399 biolink:MolecularActivity xanthommatin reductase activity Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin. MetaCyc:XANTHOMMATIN-REDUCTASE-RXN|RHEA:13417|EC:1.3.1.41|KEGG_REACTION:R03787 go-plus.json 5,12-dihydroxanthommatin:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050399 UBERON:0000963 biolink:AnatomicalEntity head sensillum go-plus.json http://purl.obolibrary.org/obo/UBERON_0000963 UBERON:0000964 biolink:AnatomicalEntity cornea the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure go-plus.json corneas|cornea of camera-type eye|tunica cornea http://purl.obolibrary.org/obo/UBERON_0000964 UBERON:0000965 biolink:AnatomicalEntity lens of camera-type eye Transparent part of camera-type eye that helps to refract light to be focused on the retina. go-plus.json crystalline lens|eye lens|camera-type eye lens|lenses|lens crystallina|lens|ocular lens http://purl.obolibrary.org/obo/UBERON_0000965 UBERON:0000966 biolink:AnatomicalEntity retina The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. go-plus.json retina of camera-type eye|inner layer of eyeball|tunica interna of eyeball|retinas|Netzhaut http://purl.obolibrary.org/obo/UBERON_0000966 GO:0050392 biolink:MolecularActivity vicianin beta-glucosidase activity Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose. RHEA:14041|MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R03642|EC:3.2.1.119 go-plus.json (R)-vicianin beta-D-glucohydrolase activity|vicianin hydrolase activity|vicianin b-glucosidase activity http://purl.obolibrary.org/obo/GO_0050392 UBERON:0000970 biolink:AnatomicalEntity eye An organ that detects light. go-plus.json light-detecting organ|visual apparatus http://purl.obolibrary.org/obo/UBERON_0000970 CHEBI:52782 biolink:ChemicalSubstance O-acyl carbohydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52782 CHEBI:37163 biolink:ChemicalSubstance glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_37163 GO:0050393 biolink:MolecularActivity vinylacetyl-CoA delta-isomerase activity Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA. RHEA:10572|EC:5.3.3.3|KEGG_REACTION:R03031|MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN go-plus.json vinylacetyl-CoA D-isomerase activity|vinylacetyl-CoA delta3-delta2-isomerase activity|vinylacetyl coenzyme A isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|vinylacetyl coenzyme A delta-isomerase activity http://purl.obolibrary.org/obo/GO_0050393 CHEBI:37164 biolink:ChemicalSubstance homopolysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37164 UBERON:0000971 biolink:AnatomicalEntity ommatidium The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells. go-plus.json omatidium|omatidia http://purl.obolibrary.org/obo/UBERON_0000971 GO:0050390 biolink:MolecularActivity valine decarboxylase activity Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2). UM-BBD_reactionID:r1052|MetaCyc:VALINE-DECARBOXYLASE-RXN|EC:4.1.1.14|KEGG_REACTION:R01437|RHEA:18989 go-plus.json leucine decarboxylase activity|L-valine carboxy-lyase activity|L-valine carboxy-lyase (2-methylpropanamine-forming) http://purl.obolibrary.org/obo/GO_0050390 UBERON:0000972 biolink:AnatomicalEntity antenna The paired, usually multiple jointed, sensory organs articulating on the procephalic region of the head capsule; its highly versatile sensory structures are capable to detect the various environmental stimuli. In the context of Drosophila refers to they are the most anterior segmented sensory appendage of the head. go-plus.json feeler http://purl.obolibrary.org/obo/UBERON_0000972 GO:0050391 biolink:MolecularActivity valine dehydrogenase (NADP) activity Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH. EC:1.4.1.8|MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN|RHEA:11156 go-plus.json L-valine:NADP+ oxidoreductase (deaminating)|valine dehydrogenase (NADP+) activity|valine dehydrogenase (nicotinanide adenine dinucleotide phosphate) http://purl.obolibrary.org/obo/GO_0050391 CHEBI:37162 biolink:ChemicalSubstance trans-2-dodecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37162 CHEBI:52785 biolink:ChemicalSubstance 2-(E)-O-feruloyl-D-galactaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52785 CHEBI:13170 biolink:ChemicalSubstance Ser-tRNA(Sec) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13170 GO:0050396 biolink:MolecularActivity vomifoliol 4'-dehydrogenase activity Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH. EC:1.1.1.221|RHEA:22804|MetaCyc:VOMIFOLIOL-4-DEHYDROGENASE-RXN|KEGG_REACTION:R04412 go-plus.json vomifoliol:NAD+ 4'-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050396 GO:0050397 biolink:MolecularActivity Watasenia-luciferin 2-monooxygenase activity Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light. MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:18057|EC:1.13.12.8 go-plus.json luciferase activity|Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Watasenia-type luciferase activity http://purl.obolibrary.org/obo/GO_0050397 GO:0050394 biolink:MolecularActivity viomycin kinase activity Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin. EC:2.7.1.103|MetaCyc:VIOMYCIN-KINASE-RXN|RHEA:20509 go-plus.json viomycin phosphotransferase activity|ATP:viomycin O-phosphotransferase activity|capreomycin phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050394 CHEBI:37165 biolink:ChemicalSubstance galactan go-plus.json http://purl.obolibrary.org/obo/CHEBI_37165 CHEBI:13172 biolink:ChemicalSubstance keto-L-sorbose go-plus.json http://purl.obolibrary.org/obo/CHEBI_13172 chebi_ph7_3 GO:0050395 biolink:MolecularActivity vitexin beta-glucosyltransferase activity Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside. EC:2.4.1.105|MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:21956|KEGG_REACTION:R03565 go-plus.json UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity|vitexin b-glucosyltransferase activity|uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity|UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050395 CHEBI:13173 biolink:ChemicalSubstance L-tagatose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13173 CHEBI:37166 biolink:ChemicalSubstance xylan go-plus.json http://purl.obolibrary.org/obo/CHEBI_37166 UBERON:0000956 biolink:AnatomicalEntity cerebral cortex The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex. go-plus.json cortex cerebri|cortex cerebralis|cortical plate (CTXpl)|cortical plate (areas)|cortex of cerebral hemisphere|pallium of the brain|brain cortex http://purl.obolibrary.org/obo/UBERON_0000956 UBERON:0000957 biolink:AnatomicalEntity lamina Any thin layer or plate. go-plus.json laminar tissue http://purl.obolibrary.org/obo/UBERON_0000957 UBERON:0000958 biolink:AnatomicalEntity medulla of organ Middle part of an organ, surrounded by the cortex. go-plus.json medulla http://purl.obolibrary.org/obo/UBERON_0000958 UBERON:0000959 biolink:AnatomicalEntity optic chiasma A decussation of the diencephalon where the fibers of the optic nerve cross go-plus.json decussation of optic nerve fibers|optic chiasm (Rufus of Ephesus)|chiasma nervorum opticorum|chiasma opticum|optic chiasm|chiasma http://purl.obolibrary.org/obo/UBERON_0000959 CHEBI:52775 biolink:ChemicalSubstance UDP-N-acetyl-2-amino-2-deoxy-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52775 UBERON:0000955 biolink:AnatomicalEntity brain The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. go-plus.json suprasegmental structures|synganglion|suprasegmental levels of nervous system|encephalon|the brain http://purl.obolibrary.org/obo/UBERON_0000955 UBERON:0000961 biolink:AnatomicalEntity thoracic ganglion The thoracic ganglia are paravertebral ganglia. The thoracic portion of the sympathetic trunk typically has 12 thoracic ganglia. Emerging from the ganglia are thoracic splancic nerves (the cardiopulmonary, the greater, lesser, and least splanchic nerves) that help provide sympathetic innervation to abdominal structures. Also, the ganglia of the thoracic sympathetic trunk have both white and gray rami communicantes. The white rami carry sympathetic fibers arising in the spinal cord into the sympathetic trunk. [WP,unvetted]. go-plus.json thoracic paravertebral ganglion|thoracic sympathetic ganglion|ganglion of thorax|ganglion thoracicum splanchnicum|thorax ganglion|thoracic splanchnic ganglion http://purl.obolibrary.org/obo/UBERON_0000961 CHEBI:52773 biolink:ChemicalSubstance alpha-D-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52773 UBERON:0000962 biolink:AnatomicalEntity nerve of cervical vertebra The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]. go-plus.json cervical spinal nerve|cervical nerve tree|nervus cervicalis|cervical nerve http://purl.obolibrary.org/obo/UBERON_0000962 GO:0001400 biolink:CellularComponent mating projection base The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone. go-plus.json base of shmoo tip|conjugation tube base http://purl.obolibrary.org/obo/GO_0001400 UBERON:0000945 biolink:AnatomicalEntity stomach An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. go-plus.json stomach chamber|ventriculus|gaster|anterior intestine|mesenteron http://purl.obolibrary.org/obo/UBERON_0000945 UBERON:0000946 biolink:AnatomicalEntity cardial valve A membranous fold of the heart that prevents reflux of fluid go-plus.json heart valve|stomodaeal valve|valve of heart|cardiac valve|heart valves|heart valve|valvule http://purl.obolibrary.org/obo/UBERON_0000946 GO:0001401 biolink:CellularComponent SAM complex A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex. go-plus.json mitochondrial sorting and assembly machinery complex|TOB complex http://purl.obolibrary.org/obo/GO_0001401 UBERON:0000947 biolink:AnatomicalEntity aorta The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation go-plus.json dorsal aorta|arteria maxima|trunk of systemic arterial tree|trunk of aortic tree http://purl.obolibrary.org/obo/UBERON_0000947 GO:0001402 biolink:BiologicalProcess signal transduction involved in filamentous growth Relaying of environmental signals promoting filamentous growth. go-plus.json MAPKKK cascade (pseudohyphal growth)|signal transduction during filamentous growth http://purl.obolibrary.org/obo/GO_0001402 UBERON:0000948 biolink:AnatomicalEntity heart A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. go-plus.json vertebrate heart|cardium|chambered heart|branchial heart http://purl.obolibrary.org/obo/UBERON_0000948 GO:0001403 biolink:BiologicalProcess invasive growth in response to glucose limitation A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae. go-plus.json colony morphology http://purl.obolibrary.org/obo/GO_0001403 goslim_yeast UBERON:0000941 biolink:AnatomicalEntity cranial nerve II Cranial nerve fiber tract which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]. go-plus.json nerve II|2n|optic nerve|optic nerve [II]|optic|cranial II|nervus opticus|nervus opticus [II]|CN-II|optic II nerve|02 optic nerve|second cranial nerve|optic II http://purl.obolibrary.org/obo/UBERON_0000941 UBERON:0000949 biolink:AnatomicalEntity endocrine system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. go-plus.json endocrine system|systema endocrinum|endocrine glandular system http://purl.obolibrary.org/obo/UBERON_0000949 CHEBI:37149 biolink:ChemicalSubstance bromobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_37149 CHEBI:37147 biolink:ChemicalSubstance dibromobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37147 CHEBI:37148 biolink:ChemicalSubstance bromoarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37148 CHEBI:37141 biolink:ChemicalSubstance organobromine compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37141 chebi_ph7_3 GO:0001408 biolink:BiologicalProcess guanine nucleotide transport The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0001408 CHEBI:13197 biolink:ChemicalSubstance ribonucleoside 3'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13197 chebi_ph7_3 CHEBI:37142 biolink:ChemicalSubstance organoiodine compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37142 chebi_ph7_3 GO:0001409 biolink:MolecularActivity guanine nucleotide transmembrane transporter activity Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0001409 UBERON:0000951 biolink:AnatomicalEntity rotator muscle of the vertebral column Any of a number of short transversospinal muscles chiefly developed in cervical, lumbar, and thoracic regions, arising from the transverse process of one vertebra and inserted into the root of the spinous process of the next two or three vertebrae above, with nerve supply from the dorsal branches of the spinal nerve, and whose actions rotate the vertebral column. go-plus.json rotator muscle http://purl.obolibrary.org/obo/UBERON_0000951 GO:0001404 biolink:BiologicalProcess obsolete invasive growth OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. go-plus.json tissue invasion|invasive growth http://purl.obolibrary.org/obo/GO_0001404 CHEBI:13193 biolink:ChemicalSubstance hydrogen acceptor go-plus.json http://purl.obolibrary.org/obo/CHEBI_13193 chebi_ph7_3 GO:0001405 biolink:CellularComponent PAM complex, Tim23 associated import motor Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix. go-plus.json mitochondrial import motor|pre-sequence translocase-associated import motor|PAM complex|presequence translocase-associated import motor http://purl.obolibrary.org/obo/GO_0001405 CHEBI:37146 biolink:ChemicalSubstance molybdopterin dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37146 GO:0001406 biolink:MolecularActivity glycerophosphodiester transmembrane transporter activity Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0001406 CHEBI:37143 biolink:ChemicalSubstance organofluorine compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37143 chebi_ph7_3 GO:0001407 biolink:BiologicalProcess glycerophosphodiester transmembrane transport The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0001407 CHEBI:27798 biolink:ChemicalSubstance nitrobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27798 chebi_ph7_3 UBERON:0010341 biolink:AnatomicalEntity 1st arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. go-plus.json mesenchyme derived from head mesoderm of mesenchyme of 1st arch http://purl.obolibrary.org/obo/UBERON_0010341 UBERON:0010344 biolink:AnatomicalEntity 3rd arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme. go-plus.json pharyngeal arch 3 mesenchyme from head mesenchyme|head mesenchyme derived arch 3 mesenchyme|mesenchyme derived from head mesoderm of mesenchyme of 3rd arch|branchial arch 3 mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010344 UBERON:0010345 biolink:AnatomicalEntity 4th arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. go-plus.json pharyngeal arch 4 mesenchyme from head mesenchyme|head mesenchyme derived arch 4 mesenchyme|mesenchyme derived from head mesoderm of mesenchyme of 4th arch|branchial arch 4 mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010345 UBERON:0010343 biolink:AnatomicalEntity 2nd arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme. go-plus.json pharyngeal arch 2 mesenchyme from head mesenchyme|head mesenchyme derived arch 2 mesenchyme|mesenchyme derived from head mesoderm of mesenchyme of 2nd arch|branchial arch 2 mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010343 UBERON:0010337 biolink:AnatomicalEntity mandibular process mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010337 UBERON:0010338 biolink:AnatomicalEntity 1st arch maxillary mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010338 UBERON:0010335 biolink:AnatomicalEntity maxillary process mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010335 UBERON:0010336 biolink:AnatomicalEntity mandibular process mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010336 UBERON:0010339 biolink:AnatomicalEntity 1st arch mandibular mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010339 CHEBI:52742 biolink:ChemicalSubstance D-ribofuranose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52742 UBERON:0010330 biolink:AnatomicalEntity eyelid mesenchyme Mesenchyme that is part of a developing eyelid. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010330 UBERON:0010333 biolink:AnatomicalEntity extraembryonic membrane mesenchyme Mesenchyme that is part of a extraembryonic membrane. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010333 UBERON:0010334 biolink:AnatomicalEntity maxillary process mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010334 UBERON:0010332 biolink:AnatomicalEntity epithelium of handplate An epithelium that is part of a handplate. go-plus.json handplate epithelium http://purl.obolibrary.org/obo/UBERON_0010332 CHEBI:37127 biolink:ChemicalSubstance 3-methylbut-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37127 CHEBI:37128 biolink:ChemicalSubstance caesium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_37128 CHEBI:37125 biolink:ChemicalSubstance 5-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37125 UBERON:0010328 biolink:AnatomicalEntity limb bud mesenchyme Mesenchyme that is part of a limb bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010328 UBERON:0010329 biolink:AnatomicalEntity paired limb/fin bud mesenchyme Mesenchyme that is part of a limb/fin bud. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010329 CHEBI:37120 biolink:ChemicalSubstance guanosine 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37120 CHEBI:37123 biolink:ChemicalSubstance nucleoside bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37123 CHEBI:37124 biolink:ChemicalSubstance guanosine bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37124 CHEBI:37121 biolink:ChemicalSubstance guanosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37121 UBERON:0000996 biolink:AnatomicalEntity vagina A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]. go-plus.json distal oviductal region|vaginae|distal portion of oviduct http://purl.obolibrary.org/obo/UBERON_0000996 CHEBI:52731 biolink:ChemicalSubstance 5-alkatrienylresorcinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52731 chebi_ph7_3 CHEBI:27775 biolink:ChemicalSubstance P(1),P(3)-bis(5'-adenosyl) triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27775 UBERON:0000997 biolink:AnatomicalEntity mammalian vulva external genital organs of the female mammal[WP]. go-plus.json vulva|puboperineal region|skin of vulva|mammalian vulva|pudendum|female pudendum|pudendum femininum|skin of female pudendum|pudendum femininum|pudendum muliebre http://purl.obolibrary.org/obo/UBERON_0000997 UBERON:0000998 biolink:AnatomicalEntity seminal vesicle Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct. go-plus.json vesicular seminalis|vesicular glands|vesicular gland|gonecyst|seminal gland|vesiculae seminales|vas efferens|glandula vesiculosa|glandula seminalis|vesiculæ seminales|vesicula seminalis http://purl.obolibrary.org/obo/UBERON_0000998 UBERON:0000999 biolink:AnatomicalEntity ejaculatory duct The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]. go-plus.json ductus ejaculatorii|ductus ejaculatorius|ductus ejaculatorii http://purl.obolibrary.org/obo/UBERON_0000999 CHEBI:27771 biolink:ChemicalSubstance 16alpha-hydroxydehydroepiandrosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27771 chebi_ph7_3 CHEBI:27772 biolink:ChemicalSubstance 4-chlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27772 chebi_ph7_3 CHEBI:27773 biolink:ChemicalSubstance cis-3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27773 UBERON:0010323 biolink:AnatomicalEntity cranial skeletal system Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. go-plus.json osteocranium|cranium|cranial skeleton http://purl.obolibrary.org/obo/UBERON_0010323 UBERON:0010321 biolink:AnatomicalEntity skeletal element of eye region A skeletal element that is part of a orbital region. go-plus.json skeletal element of orbital region|eye skeleton|ocular skeleton http://purl.obolibrary.org/obo/UBERON_0010321 CHEBI:350546 biolink:ChemicalSubstance serotonin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_350546 chebi_ph7_3 CHEBI:27770 biolink:ChemicalSubstance nonanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27770 UBERON:0010316 biolink:AnatomicalEntity germ layer / neural crest go-plus.json http://purl.obolibrary.org/obo/UBERON_0010316 UBERON:0010313 biolink:AnatomicalEntity neural crest-derived structure An anatomical structure that develops from the neural crest. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010313 UBERON:0010314 biolink:AnatomicalEntity structure with developmental contribution from neural crest An anatomical structure that has some part that develops from the neural crest. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010314 CHEBI:13166 biolink:ChemicalSubstance Sec-tRNA(Sec) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13166 UBERON:0000989 biolink:AnatomicalEntity penis A intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination go-plus.json phallus|penes http://purl.obolibrary.org/obo/UBERON_0000989 CHEBI:52726 biolink:ChemicalSubstance proteasome inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_52726 CHEBI:27786 biolink:ChemicalSubstance hydroxocobalamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27786 UBERON:0000985 biolink:AnatomicalEntity axillary vein Vein that drains the axilla go-plus.json subcostal vein|vena axillaris http://purl.obolibrary.org/obo/UBERON_0000985 CHEBI:27787 biolink:ChemicalSubstance 15-cis-phytoene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27787 chebi_ph7_3 UBERON:0000987 biolink:AnatomicalEntity haltere The capitate stalk on both sides of the thorax having developed from the dorsal metathoracic wing-buds, it is freely movable and capable of vibration, representing the hind wing of Diptera; used for flight balance. go-plus.json balancer organ http://purl.obolibrary.org/obo/UBERON_0000987 UBERON:0000988 biolink:AnatomicalEntity pons The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. go-plus.json pons Varolii|pons cerebri|pons of Varolius http://purl.obolibrary.org/obo/UBERON_0000988 CHEBI:27789 biolink:ChemicalSubstance 1,2-dichloroethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_27789 chebi_ph7_3 CHEBI:27784 biolink:ChemicalSubstance gentamycin C1a go-plus.json http://purl.obolibrary.org/obo/CHEBI_27784 UBERON:0010312 biolink:AnatomicalEntity immature eye Developing anatomical structure that develops into the eyeball and associated structures. go-plus.json future eye http://purl.obolibrary.org/obo/UBERON_0010312 CHEBI:27780 biolink:ChemicalSubstance detergent go-plus.json http://purl.obolibrary.org/obo/CHEBI_27780 UBERON:0010310 biolink:AnatomicalEntity nictitating membrane lamina thin cartilage element that stiffens the nictitating membrane. go-plus.json cartilago intercipiens|nictitating membrane cartilage http://purl.obolibrary.org/obo/UBERON_0010310 CHEBI:27781 biolink:ChemicalSubstance myristoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27781 CHEBI:37105 biolink:ChemicalSubstance 2-aminopteridin-4(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_37105 chebi_ph7_3 UBERON:0010304 biolink:AnatomicalEntity non-keratinized stratified squamous epithelium Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus. go-plus.json stratified squamous nonkeratinizing epithelium|nonkeratinizing stratified squamous epithelium|stratified squamous non-keratinized epithelium|epithelium stratificatum squamosum noncornificatum http://purl.obolibrary.org/obo/UBERON_0010304 UBERON:0010305 biolink:AnatomicalEntity subdivision of conjunctiva One of the three major regions of the conjunctiva. go-plus.json conjunctiva region|region of conjunctiva http://purl.obolibrary.org/obo/UBERON_0010305 UBERON:0010302 biolink:AnatomicalEntity amnioserosa A single extraembryonic epithelium, which closes the germband dorsally. go-plus.json amnion-serosa http://purl.obolibrary.org/obo/UBERON_0010302 UBERON:0010303 biolink:AnatomicalEntity extraembryonic epithelium An epithelium that is part of a extraembryonic structure. go-plus.json extra-embryonic epithelium http://purl.obolibrary.org/obo/UBERON_0010303 CHEBI:37107 biolink:ChemicalSubstance 7-methyl-3-oxooctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37107 CHEBI:37108 biolink:ChemicalSubstance 7-methyloctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37108 UBERON:0000992 biolink:AnatomicalEntity ovary the gonad of a female organism which contains germ cells go-plus.json gonada of female organism reproductive system|female gonad|female organism genitalia gonada|reproductive system of female organism gonad|gonad of female organism genitalia|gonad of female reproductive system|gonad of genitalia of female organism|ovum-producing ovary|reproductive system of female organism gonada|female organism genitalia gonad|gonada of reproductive system of female organism|female reproductive system gonad|genitalia of female organism gonad|gonad of female organism reproductive system|ovarium|gonada of female organism genitalia|female organism reproductive system gonad|gonada of genitalia of female organism|gonada of female reproductive system|female organism reproductive system gonada|animal ovary|gonad of reproductive system of female organism|ovaries|genitalia of female organism gonada|female reproductive system gonada http://purl.obolibrary.org/obo/UBERON_0000992 UBERON:0000993 biolink:AnatomicalEntity oviduct A tube or collection of tubes in an animal from the ovaries to the outside of the body. go-plus.json tuba uterinae|uterine tube|tubular parts of female reproductive system|tuba uterina|oviducts|female reproductive tracts|ovarian tube|ovarian duct http://purl.obolibrary.org/obo/UBERON_0000993 UBERON:0000994 biolink:AnatomicalEntity spermathecum An organ of the female reproductive tract that functions to receive and store sperm from the male, and can sometimes be the site of fertilization when the oocytes are ready. go-plus.json receptaculum seminis|spermathecae|spermatheca|seminal receptacle http://purl.obolibrary.org/obo/UBERON_0000994 UBERON:0000995 biolink:AnatomicalEntity uterus the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth go-plus.json http://purl.obolibrary.org/obo/UBERON_0000995 CHEBI:37102 biolink:ChemicalSubstance nucleoside pentaphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37102 UBERON:0000990 biolink:AnatomicalEntity reproductive system Anatomical system that has as its parts the organs concerned with reproduction. go-plus.json Geschlechtsorgan|genital tract|reproductive tract|animal reproductive system|organa genitalia|reproductive tissue|genital system|genitalia|systemata genitalia http://purl.obolibrary.org/obo/UBERON_0000990 UBERON:0000991 biolink:AnatomicalEntity gonad Reproductive organ that produces and releases eggs (ovary) or sperm (testis). go-plus.json gonads|gonada http://purl.obolibrary.org/obo/UBERON_0000991 CHEBI:37100 biolink:ChemicalSubstance (S)-3-hydroxyoctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37100 GO:0050301 biolink:MolecularActivity streptomycin-6-phosphatase activity Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin. MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN|EC:3.1.3.39|KEGG_REACTION:R02228|RHEA:10688 go-plus.json streptomycin-6-phosphate phosphohydrolase activity|streptomycin-6-P phosphohydrolase activity|streptomycin 6-phosphate phosphohydrolase activity|streptomycin 6-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0050301 GO:0050302 biolink:MolecularActivity indole-3-acetaldehyde oxidase activity Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+). KEGG_REACTION:R02681|EC:1.2.3.7|RHEA:16277|MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN go-plus.json (indol-3-yl)acetaldehyde:oxygen oxidoreductase activity|AO1|IAAld oxidase activity|IAA oxidase activity|indole-3-acetaldehyde:oxygen oxidoreductase activity|indoleacetaldehyde oxidase activity http://purl.obolibrary.org/obo/GO_0050302 GO:0050300 biolink:MolecularActivity aminoglycoside 6-kinase activity Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate. EC:2.7.1.72|KEGG_REACTION:R02225|RHEA:22268|MetaCyc:STREPTOMYCIN-6-KINASE-RXN go-plus.json streptidine kinase activity|streptomycin 6-O-phosphotransferase activity|streptomycin 6-phosphotransferase activity|SM 6-kinase activity|streptomycin 6-kinase activity|ATP:streptomycin 6-phosphotransferase activity|APH(6) activity|streptidine kinase (phosphorylating)|streptomycin 6-kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0050300 GO:0050305 biolink:MolecularActivity strombine dehydrogenase activity Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate. RHEA:14061|MetaCyc:STROMBINE-DEHYDROGENASE-RXN|KEGG_REACTION:R00368|EC:1.5.1.22 go-plus.json strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity|N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity|N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming) http://purl.obolibrary.org/obo/GO_0050305 GO:0050306 biolink:MolecularActivity sucrose 1F-fructosyltransferase activity Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose. RHEA:23312|MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN|EC:2.4.1.99 go-plus.json sucrose-sucrose 1-fructosyltransferase activity|sucrose:sucrose 1'-beta-D-fructosyltransferase activity|sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity|sucrose:sucrose 1-fructosyltransferase activity|sucrose:sucrose fructosyltransferase activity|SST activity|sucrose 1(F)-fructosyltransferase activity|sucrose:sucrose 1F-beta-D-fructosyltransferase activity http://purl.obolibrary.org/obo/GO_0050306 GO:0050303 biolink:MolecularActivity lysine 6-dehydrogenase activity Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine. EC:1.4.1.18|MetaCyc:LYSINE-6-DEHYDROGENASE-RXN|RHEA:12408|MetaCyc:PWY-5314 go-plus.json L-lysine:NAD+ 6-oxidoreductase (deaminating)|L-lysine epsilon-dehydrogenase activity|LysDH activity|L-lysine 6-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050303 CHEBI:86051 biolink:ChemicalSubstance O-octanoyl-D-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86051 chebi_ph7_3 GO:0050304 biolink:MolecularActivity nitrous-oxide reductase activity Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide. EC:1.7.2.4|MetaCyc:RXN-12130|KEGG_REACTION:R02804|RHEA:43108 go-plus.json N2O reductase activity|nitrogen:acceptor oxidoreductase (N2O-forming)|nitrous oxide reductase activity|nitrogen:(acceptor) oxidoreductase (N2O-forming) http://purl.obolibrary.org/obo/GO_0050304 CHEBI:62081 biolink:ChemicalSubstance 1,1-diunsubstituted alkanesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62081 chebi_ph7_3 CL:0000006 biolink:Cell neuronal receptor cell go-plus.json neuronal receptor cell (sensu Animalia) http://purl.obolibrary.org/obo/CL_0000006 CHEBI:86053 biolink:ChemicalSubstance 18-hydroxyoleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86053 GO:0050309 biolink:MolecularActivity sugar-terminal-phosphatase activity Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate. EC:3.1.3.58 go-plus.json xylitol-5-phosphatase activity|sugar-omega-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050309 CL:0000007 biolink:Cell early embryonic cell (metazoa) A cell found in the embryo before the formation of all the gem layers is complete. go-plus.json http://purl.obolibrary.org/obo/CL_0000007 PR:000024025 biolink:Protein methyl-accepting chemotaxis protein IV A protein that is a translation product of the Escherichia coli K-12 tap gene or a 1:1 ortholog thereof. go-plus.json tap|MCP-IV|dipeptide chemoreceptor protein http://purl.obolibrary.org/obo/PR_000024025 GO:0050307 biolink:MolecularActivity sucrose-phosphate phosphatase activity Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate. KEGG_REACTION:R06211|RHEA:19289|MetaCyc:SUCROSE-PHOSPHATASE-RXN|KEGG_REACTION:R00805|EC:3.1.3.24 go-plus.json sucrose-6F-phosphate phosphohydrolase activity|sucrose-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050307 CL:0000008 biolink:Cell migratory cranial neural crest cell Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination. go-plus.json http://purl.obolibrary.org/obo/CL_0000008 CHEBI:86055 biolink:ChemicalSubstance ethyl hexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86055 chebi_ph7_3 GO:0050308 biolink:MolecularActivity sugar-phosphatase activity Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate. MetaCyc:SUGAR-PHOSPHATASE-RXN|KEGG_REACTION:R00804|EC:3.1.3.23 go-plus.json sugar-phosphate phosphohydrolase activity|sugar-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0050308 CHEBI:62089 biolink:ChemicalSubstance EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62089 CL:0000000 biolink:Cell cell A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/CL_0000000 CL:0000003 biolink:Cell native cell A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). go-plus.json cell in vivo http://purl.obolibrary.org/obo/CL_0000003 CL:0000005 biolink:Cell fibroblast neural crest derived Any fibroblast that is deriived from the neural crest. go-plus.json http://purl.obolibrary.org/obo/CL_0000005 GO:0050312 biolink:MolecularActivity sulfoacetaldehyde lyase activity Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite. EC:4.4.1.- go-plus.json sulphoacetaldehyde lyase activity http://purl.obolibrary.org/obo/GO_0050312 GO:0050313 biolink:MolecularActivity sulfur dioxygenase activity Catalysis of the reaction: sulfur + O2 + H2O = sulfite. MetaCyc:FESGSHTHIO-RXN|RHEA:12981|Reactome:R-HSA-1614605|EC:1.13.11.18 go-plus.json sulfur oxygenase activity|S-sulfanylglutathione:oxygen oxidoreductase activity|sulfur:oxygen oxidoreductase activity|sulphur dioxygenase activity http://purl.obolibrary.org/obo/GO_0050313 CHEBI:62090 biolink:ChemicalSubstance germacra-1(10),4,11(13)-trien-12-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62090 chebi_ph7_3 GO:0050310 biolink:MolecularActivity sulfite dehydrogenase activity Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c. MetaCyc:SULFITE-DEHYDROGENASE-RXN|EC:1.8.2.1|RHEA:14281 go-plus.json sulfite:ferricytochrome-c oxidoreductase activity|sulfite cytochrome c reductase activity|sulphite dehydrogenase activity|sulfite-cytochrome c oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050310 GO:0050311 biolink:MolecularActivity sulfite reductase (ferredoxin) activity Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin. MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN|EC:1.8.7.1|RHEA:23132 go-plus.json ferredoxin-sulfite reductase activity|sulphite reductase (ferredoxin) activity|hydrogen-sulfide:ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050311 GO:0050316 biolink:MolecularActivity T2-induced deoxynucleotide kinase activity Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP. MetaCyc:GMKALT-RXN|RHEA:12697|EC:2.7.4.12 go-plus.json ATP:(d)NMP phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050316 GO:0050317 biolink:MolecularActivity tagatose kinase activity Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+). KEGG_REACTION:R02927|RHEA:15513|EC:2.7.1.101|MetaCyc:TAGATOSE-KINASE-RXN go-plus.json tagatose 6-phosphate kinase (phosphorylating)|D-tagatose 6-phosphate kinase activity|ATP:D-tagatose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050317 GO:0050314 biolink:MolecularActivity sym-norspermidine synthase activity Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+). EC:2.5.1.23|RHEA:23244|MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN|KEGG_REACTION:R03271 go-plus.json S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity http://purl.obolibrary.org/obo/GO_0050314 CHEBI:86040 biolink:ChemicalSubstance 3-hydroxyoctanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86040 chebi_ph7_3 CHEBI:62091 biolink:ChemicalSubstance germacra-1(10),4,11(13)-trien-12-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_62091 chebi_ph7_3 CHEBI:86041 biolink:ChemicalSubstance 3-hydroxydecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86041 chebi_ph7_3 GO:0050315 biolink:MolecularActivity synephrine dehydratase activity Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium. EC:4.2.1.88|KEGG_REACTION:R03359|RHEA:32203|MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN go-plus.json 1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming) http://purl.obolibrary.org/obo/GO_0050315 CHEBI:86042 biolink:ChemicalSubstance 2-methyl-3-oxopalmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86042 chebi_ph7_3 CL:0000017 biolink:Cell spermatocyte A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. go-plus.json http://purl.obolibrary.org/obo/CL_0000017 CL:0000018 biolink:Cell spermatid A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. go-plus.json nematoblast http://purl.obolibrary.org/obo/CL_0000018 CHEBI:86043 biolink:ChemicalSubstance O-acyl-D-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86043 chebi_ph7_3 GO:0050318 biolink:MolecularActivity tannase activity Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+). EC:3.1.1.20|MetaCyc:TANNASE-RXN|KEGG_REACTION:R00053|RHEA:16365 go-plus.json tannin acylhydrolase activity|tannase S|tannin acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0050318 CHEBI:86044 biolink:ChemicalSubstance 18-hydroxyoleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86044 chebi_ph7_3 CL:0000019 biolink:Cell sperm A mature male germ cell that develops from a spermatid. go-plus.json spermatozoon|spermatozoid|sperm cell http://purl.obolibrary.org/obo/CL_0000019 GO:0050319 biolink:MolecularActivity tartrate decarboxylase activity Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2). MetaCyc:TARTRATE-DECARBOXYLASE-RXN|RHEA:13317|EC:4.1.1.73|KEGG_REACTION:R01751 go-plus.json (R,R)-tartrate carboxy-lyase (D-glycerate-forming)|(R,R)-tartrate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0050319 CHEBI:86045 biolink:ChemicalSubstance O-acetyl-D-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86045 chebi_ph7_3 CHEBI:86046 biolink:ChemicalSubstance 18-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86046 chebi_ph7_3 CHEBI:86048 biolink:ChemicalSubstance 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86048 chebi_ph7_3 CL:0000011 biolink:Cell migratory trunk neural crest cell Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination. go-plus.json http://purl.obolibrary.org/obo/CL_0000011 CL:0000014 biolink:Cell germ line stem cell go-plus.json germline stem cell http://purl.obolibrary.org/obo/CL_0000014 CL:0000015 biolink:Cell male germ cell Male germ cell is a germ cell that supports male gamete production. go-plus.json http://purl.obolibrary.org/obo/CL_0000015 CL:0000016 biolink:Cell male germ line stem cell go-plus.json http://purl.obolibrary.org/obo/CL_0000016 GO:0050323 biolink:MolecularActivity taurine dehydrogenase activity Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde. KEGG_REACTION:R07167|MetaCyc:TAURINE-DEHYDROGENASE-RXN|EC:1.4.99.2|RHEA:18709 go-plus.json taurine:(acceptor) oxidoreductase (deaminating)|taurine:acceptor oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0050323 GO:0050324 biolink:MolecularActivity taurocyamine kinase activity Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+). MetaCyc:TAUROCYAMINE-KINASE-RXN|RHEA:22516|KEGG_REACTION:R03785|EC:2.7.3.4 go-plus.json taurocyamine phosphotransferase activity|ATP:taurocyamine N-phosphotransferase activity|ATP:taurocyamine phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050324 GO:0050321 biolink:MolecularActivity tau-protein kinase activity Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. EC:2.7.11.26|MetaCyc:TAU-PROTEIN-KINASE-RXN go-plus.json TPK I|tau protein kinase activity|protein tau kinase activity|tau kinase activity|TPK II|TPK|[Tau protein] kinase activity|tau-tubulin kinase activity|glycogen synthase kinase-3beta activity|CDK5/p23|TTK|tau-protein kinase I activity|cdk5/p20|brain protein kinase PK40erk activity|STK31|GSK|ATP:tau-protein O-phosphotransferase activity|tau-protein kinase II activity http://purl.obolibrary.org/obo/GO_0050321 GO:0050322 biolink:MolecularActivity taurine-2-oxoglutarate transaminase activity Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate. RHEA:16353|MetaCyc:RXN-2301|EC:2.6.1.55 go-plus.json taurine--glutamate transaminase activity|taurine aminotransferase activity|taurine:2-oxoglutarate aminotransferase activity|taurine transaminase activity|taurine--alpha-ketoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0050322 CHEBI:86071 biolink:ChemicalSubstance caffeyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86071 chebi_ph7_3 GO:0050327 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050327 GO:0050328 biolink:MolecularActivity tetrahydroberberine oxidase activity Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2. EC:1.3.3.8|MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN|RHEA:13489 go-plus.json (S)-tetrahydroberberine:oxygen oxidoreductase activity|(S)-THB oxidase activity|THB oxidase activity http://purl.obolibrary.org/obo/GO_0050328 GO:0050325 biolink:MolecularActivity tauropine dehydrogenase activity Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine. RHEA:12580|MetaCyc:TAUROPINE-DEHYDROGENASE-RXN|EC:1.5.1.23|KEGG_REACTION:R01683 go-plus.json N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)|2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming) http://purl.obolibrary.org/obo/GO_0050325 GO:0050326 biolink:MolecularActivity taxifolin 8-monooxygenase activity Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O. EC:1.14.13.19|MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN go-plus.json taxifolin hydroxylase activity|taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating) http://purl.obolibrary.org/obo/GO_0050326 CHEBI:86074 biolink:ChemicalSubstance (24S,25)-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86074 chebi_ph7_3 GO:0050329 biolink:MolecularActivity tetrahydroxypteridine cycloisomerase activity Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate. EC:5.5.1.3|KEGG_REACTION:R04154|RHEA:18097|MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN go-plus.json tetrahydroxypteridine lyase (isomerizing) http://purl.obolibrary.org/obo/GO_0050329 CHEBI:86077 biolink:ChemicalSubstance O-butenoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86077 chebi_ph7_3 GO:0015997 biolink:MolecularActivity obsolete ubiquinone biosynthetic process monooxygenase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ubiquinone biosynthetic process monooxygenase activity|coenzyme Q biosynthetic process monooxygenase activity|coenzyme Q biosynthesis monooxygenase activity|ubiquinone formation monooxygenase activity|ubiquinone synthesis monooxygenase activity|ubiquinone anabolism monooxygenase activity http://purl.obolibrary.org/obo/GO_0015997 GO:0015998 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015998 GO:0015999 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015999 PR:000000033 biolink:Protein tumor necrosis factor, TNF-like A protein with a core domain composition consisting of an N-terminal cytosolic domain, a type II transmembrane domain and a C-terminal TNF domain (Pfam:PF00229). go-plus.json http://purl.obolibrary.org/obo/PR_000000033 GO:0015993 biolink:BiologicalProcess obsolete molecular hydrogen transport OBSOLETE. The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015993 PR:000000034 biolink:Protein BMP A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors. go-plus.json http://purl.obolibrary.org/obo/PR_000000034 GO:0015994 biolink:BiologicalProcess chlorophyll metabolic process The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment. go-plus.json chlorophyll metabolism http://purl.obolibrary.org/obo/GO_0015994 GO:0015995 biolink:BiologicalProcess chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors. MetaCyc:CHLOROPHYLL-SYN go-plus.json chlorophyll anabolism|chlorophyll synthesis|chlorophyll biosynthesis|chlorophyll formation http://purl.obolibrary.org/obo/GO_0015995 GO:0015996 biolink:BiologicalProcess chlorophyll catabolic process The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products. go-plus.json chlorophyll degradation|chlorophyll breakdown|chlorophyll catabolism http://purl.obolibrary.org/obo/GO_0015996 CHEBI:37097 biolink:ChemicalSubstance adenosine 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37097 CHEBI:37098 biolink:ChemicalSubstance 3-hydroxyoctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37098 GO:0015990 biolink:BiologicalProcess electron transport coupled proton transport The transport of protons against an electrochemical gradient, using energy from electron transport. go-plus.json http://purl.obolibrary.org/obo/GO_0015990 GO:0015991 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015991 GO:0015992 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015992 CHEBI:37096 biolink:ChemicalSubstance adenosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37096 GO:0050320 biolink:MolecularActivity tartrate epimerase activity Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate. KEGG_REACTION:R02546|RHEA:22212|EC:5.1.2.5|MetaCyc:TARTRATE-EPIMERASE-RXN go-plus.json tartaric racemase activity http://purl.obolibrary.org/obo/GO_0050320 CHEBI:37099 biolink:ChemicalSubstance (R)-3-hydroxyoctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37099 GO:0050334 biolink:MolecularActivity thiaminase activity Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+). EC:3.5.99.2|RHEA:17509|KEGG_REACTION:R02133|MetaCyc:THIAMINASE-RXN go-plus.json thiaminase II activity http://purl.obolibrary.org/obo/GO_0050334 GO:0050335 biolink:MolecularActivity thiocyanate isomerase activity Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate. MetaCyc:THIOCYANATE-ISOMERASE-RXN|RHEA:10004|KEGG_REACTION:R04010|EC:5.99.1.1 go-plus.json isothiocyanate isomerase activity|benzyl-thiocyanate isomerase activity http://purl.obolibrary.org/obo/GO_0050335 GO:0050332 biolink:MolecularActivity thiamine pyridinylase activity Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine. KEGG_REACTION:R02863|MetaCyc:THIAMIN-PYRIDINYLASE-RXN|RHEA:17697|EC:2.5.1.2 go-plus.json thiamin pyridinolase activity|thiaminase I activity|thiamine pyridinolase activity|thiamine hydrolase activity|thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamin pyridinylase activity|thiamin hydrolase activity|pyrimidine transferase activity|thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity http://purl.obolibrary.org/obo/GO_0050332 GO:0050333 biolink:MolecularActivity thiamin-triphosphatase activity Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate. EC:3.6.1.28|RHEA:11744|Reactome:R-HSA-965067|KEGG_REACTION:R00618|MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN go-plus.json thiamine-triphosphate phosphohydrolase activity|ThTPase activity|thiamine-triphosphatase activity http://purl.obolibrary.org/obo/GO_0050333 GO:0050338 biolink:MolecularActivity thiosulfate dehydrogenase activity Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c. RHEA:20549|MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN|EC:1.8.2.2 go-plus.json thiosulphate dehydrogenase activity|thiosulfate:ferricytochrome-c oxidoreductase activity|tetrathionate synthase activity|thiosulfate oxidase activity|thiosulfate-oxidizing enzyme|thiosulfate-acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050338 GO:0050339 biolink:MolecularActivity thymidine-triphosphatase activity Catalysis of the reaction: dTTP + H2O = dTDP + phosphate. EC:3.6.1.39|RHEA:19013|MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN go-plus.json thymidine triphosphate nucleotidohydrolase activity|deoxythymidine-5'-triphosphatase activity|dTTPase activity|dTTP nucleotidohydrolase activity http://purl.obolibrary.org/obo/GO_0050339 GO:0050336 biolink:MolecularActivity thioethanolamine S-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA. MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN|EC:2.3.1.11|KEGG_REACTION:R03668|RHEA:23280 go-plus.json thioltransacetylase B activity|acetyl-CoA:thioethanolamine S-acetyltransferase activity|acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity|thioethanolamine acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050336 CHEBI:86062 biolink:ChemicalSubstance abietatriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_86062 chebi_ph7_3 GO:0050337 biolink:MolecularActivity thiosulfate-thiol sulfurtransferase activity Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide. Reactome:R-HSA-1655879|RHEA:14505|EC:2.8.1.3|MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN go-plus.json thiosulphate-thiol sulphurtransferase activity|thiosulfate:thiol sulfurtransferase activity|sulfane sulfurtransferase activity|sulfane reductase activity|glutathione-dependent thiosulfate reductase activity http://purl.obolibrary.org/obo/GO_0050337 CHEBI:86066 biolink:ChemicalSubstance O-tetradecenoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86066 chebi_ph7_3 PR:000000046 biolink:Protein TGF-beta A TGF-beta-like cystine-knot cytokine whose propeptide region is a latent associated peptide (LAP) that remains associated to the mature TGF-beta after cleavage and secretion, keeping TGF-beta inactive. TGF-beta is the founding member of the cystine-knot cytokine family, and is related to the activin/inhibin, anti-Muellerian hormone, and bone morphogenic protein families, which are all involved in the regulation of cell growth and differentiation. go-plus.json transforming growth factor beta http://purl.obolibrary.org/obo/PR_000000046 GO:0050330 biolink:MolecularActivity theanine hydrolase activity Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine. KEGG_REACTION:R02930|EC:3.5.1.65|RHEA:18013|MetaCyc:THEANINE-HYDROLASE-RXN go-plus.json N5-ethyl-L-glutamine amidohydrolase activity|L-theanine amidohydrolase activity|5-N-ethyl-L-glutamine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050330 GO:0050331 biolink:MolecularActivity thiamine-diphosphate kinase activity Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate. Reactome:R-HSA-997381|EC:2.7.4.15|MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN|RHEA:11240 go-plus.json protein bound thiamin diphosphate:ATP phosphoryltransferase activity|TDP kinase activity|thiamin diphosphate kinase activity|ATP:thiamine-diphosphate phosphotransferase activity|thiamin pyrophosphate kinase activity|thiamine diphosphate kinase activity|thiamin diphosphate phosphotransferase activity|thiamin-diphosphate kinase activity|ATP:thiamin-diphosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050331 GO:0050345 biolink:MolecularActivity trans-epoxysuccinate hydrolase activity Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate. MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN|KEGG_REACTION:R02547|RHEA:20740|EC:3.3.2.4 go-plus.json trans-2,3-epoxysuccinate hydrolase activity|tartrate epoxydase activity|trans-epoxysuccinate hydratase activity http://purl.obolibrary.org/obo/GO_0050345 GO:0050346 biolink:MolecularActivity trans-L-3-hydroxyproline dehydratase activity Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+). MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN|EC:4.2.1.77|RHEA:10320|KEGG_REACTION:R04374 go-plus.json trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)|trans-L-3-hydroxyproline hydro-lyase activity http://purl.obolibrary.org/obo/GO_0050346 GO:0050343 biolink:MolecularActivity trans-2-enoyl-CoA reductase (NAD+) activity Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH. MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN|RHEA:18177|EC:1.3.1.44 go-plus.json acyl-CoA:NAD+ trans-2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050343 GO:0050344 biolink:MolecularActivity trans-cinnamate 2-monooxygenase activity Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+). EC:1.14.13.14|RHEA:10956|MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R02254 go-plus.json cinnamate 2-hydroxylase activity|trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)|cinnamic 2-hydroxylase activity|cinnamic acid 2-hydroxylase activity|cinnamate 2-monooxygenase activity|trans-cinnamic acid 2-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050344 GO:0050349 biolink:MolecularActivity triacetate-lactonase activity Catalysis of the reaction: H(2)O + triacetate lactone = triacetate. MetaCyc:TRIACETATE-LACTONASE-RXN|RHEA:22260|EC:3.1.1.38|KEGG_REACTION:R03702 go-plus.json triacetolactone lactonohydrolase activity|triacetate lactone hydrolase activity|triacetic lactone hydrolase activity|TAL hydrolase activity|triacetic acid lactone hydrolase activity http://purl.obolibrary.org/obo/GO_0050349 CHEBI:86094 biolink:ChemicalSubstance 1-tetradecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86094 chebi_ph7_3 GO:0050347 biolink:MolecularActivity trans-octaprenyltranstransferase activity Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate. RHEA:11324|KEGG_REACTION:R07267 go-plus.json SPP synthase activity|(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity|terpenyl pyrophosphate synthetase activity|trans-prenyltransferase activity|terpenoidallyltransferase activity|all-trans-nonaprenyl-diphosphate synthase activity|solanesyl-diphosphate synthase activity|solanesyl pyrophosphate synthetase activity|polyprenylpyrophosphate synthetase activity|nonaprenyl pyrophosphate synthetase activity http://purl.obolibrary.org/obo/GO_0050347 CHEBI:37080 biolink:ChemicalSubstance acrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37080 chebi_ph7_3 GO:0050348 biolink:MolecularActivity trehalose O-mycolyltransferase activity Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose. EC:2.3.1.122|MetaCyc:RXN1G-874|KEGG_REACTION:R07248|RHEA:23472 go-plus.json alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity|alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity http://purl.obolibrary.org/obo/GO_0050348 CHEBI:86096 biolink:ChemicalSubstance (25R)-3beta-hydroxycholest-5-en-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_86096 chebi_ph7_3 CHEBI:37081 biolink:ChemicalSubstance 3-aminobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37081 CHEBI:86098 biolink:ChemicalSubstance (25R)-3beta-hydroxycholest-5-en-26-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86098 chebi_ph7_3 GO:0015979 biolink:BiologicalProcess photosynthesis The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. Wikipedia:Photosynthesis go-plus.json http://purl.obolibrary.org/obo/GO_0015979 goslim_plant|goslim_pir|goslim_metagenomics|goslim_generic|goslim_chembl PR:000024067 biolink:Protein homoserine kinase A protein that is a translation product of the Escherichia coli K-12 thrB gene or a 1:1 ortholog thereof. go-plus.json thrB|HK|HSK http://purl.obolibrary.org/obo/PR_000024067 GO:0015975 biolink:BiologicalProcess energy derivation by oxidation of reduced inorganic compounds The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released. Wikipedia:Lithotrophy go-plus.json lithotrophy|chemolithotrophy|chemolithotrophie http://purl.obolibrary.org/obo/GO_0015975 GO:0015976 biolink:BiologicalProcess carbon utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism. Wikipedia:Heterotroph go-plus.json carbon utilization by utilization of organic compounds|heterotrophy http://purl.obolibrary.org/obo/GO_0015976 goslim_pir|goslim_chembl GO:0015977 biolink:BiologicalProcess carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates). Wikipedia:Carbon_fixation go-plus.json autotrophic CO2 fixation|autotrophy|carbon dioxide fixation|autotrophic CO2 fixation pathway http://purl.obolibrary.org/obo/GO_0015977 GO:0015978 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015978 GO:0015971 biolink:BiologicalProcess guanosine tetraphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. go-plus.json guanosine tetraphosphate (5'-ppGpp-3') catabolic process|guanosine tetraphosphate catabolism|guanosine tetraphosphate degradation|guanosine tetraphosphate breakdown|guanosine tetraphosphate (5'-ppGpp-3') catabolism http://purl.obolibrary.org/obo/GO_0015971 GO:0015972 biolink:BiologicalProcess guanosine pentaphosphate metabolic process The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates. go-plus.json guanosine pentaphosphate (5'-pppGpp-3') metabolic process|guanosine pentaphosphate metabolism|guanosine pentaphosphate (5'-pppGpp-3') metabolism http://purl.obolibrary.org/obo/GO_0015972 GO:0015973 biolink:BiologicalProcess guanosine pentaphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates. go-plus.json guanosine pentaphosphate biosynthesis|guanosine pentaphosphate (5'-pppGpp-3') biosynthesis|guanosine pentaphosphate (5'-pppGpp-3') biosynthetic process|guanosine pentaphosphate anabolism|guanosine pentaphosphate synthesis|guanosine pentaphosphate formation http://purl.obolibrary.org/obo/GO_0015973 GO:0015974 biolink:BiologicalProcess guanosine pentaphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates. go-plus.json guanosine pentaphosphate degradation|guanosine pentaphosphate (5'-pppGpp-3') catabolic process|guanosine pentaphosphate breakdown|guanosine pentaphosphate catabolism|guanosine pentaphosphate (5'-pppGpp-3') catabolism http://purl.obolibrary.org/obo/GO_0015974 CHEBI:37075 biolink:ChemicalSubstance ribonucleoside 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37075 CHEBI:37076 biolink:ChemicalSubstance ribonucleoside 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37076 GO:0015970 biolink:BiologicalProcess guanosine tetraphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. go-plus.json guanosine tetraphosphate anabolism|guanosine tetraphosphate biosynthesis|guanosine tetraphosphate synthesis|guanosine tetraphosphate formation|guanosine tetraphosphate (5'-ppGpp-3') biosynthetic process|guanosine tetraphosphate (5'-ppGpp-3') biosynthesis http://purl.obolibrary.org/obo/GO_0015970 GO:0050341 biolink:MolecularActivity thymine dioxygenase activity Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2. MetaCyc:THYMINE-DIOXYGENASE-RXN|EC:1.14.11.6|RHEA:10316 go-plus.json 5-hydroxy-methyluracil dioxygenase activity|5-hydroxymethyluracil oxygenase activity|thymine,2-oxoglutarate dioxygenase activity|thymine 7-hydroxylase activity|thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating) http://purl.obolibrary.org/obo/GO_0050341 CHEBI:37079 biolink:ChemicalSubstance 2-methylacetoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37079 GO:0050342 biolink:MolecularActivity tocopherol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol. MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.95|RHEA:24012 go-plus.json gamma-tocopherol methyltransferase activity|S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0050342 CHEBI:37077 biolink:ChemicalSubstance ribonucleoside 5'-tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37077 GO:0050340 biolink:MolecularActivity thymidylate 5'-phosphatase activity Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate. RHEA:11080|EC:3.1.3.35|MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN go-plus.json deoxythymidylate phosphohydrolase activity|thymidylate 5'-phosphohydrolase activity|thymidylate 5'-nucleotidase activity|deoxythymidylic 5'-nucleotidase activity|thymidylate 5' phosphatase activity|dTMPase activity|thymidylate nucleotidase activity|deoxythymidylate 5'-nucleotidase activity http://purl.obolibrary.org/obo/GO_0050340 GO:0050356 biolink:MolecularActivity tropine dehydrogenase activity Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone. MetaCyc:TROPINE-DEHYDROGENASE-RXN|KEGG_REACTION:R02832|RHEA:18357|EC:1.1.1.206 go-plus.json tropine:NADP+ 3alpha-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050356 GO:0050357 biolink:MolecularActivity tropinesterase activity Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine. MetaCyc:TROPINESTERASE-RXN|EC:3.1.1.10|RHEA:23304|KEGG_REACTION:R03563 go-plus.json tropine esterase activity|atropine esterase activity|atropine acylhydrolase activity|atropinesterase activity|atropinase activity http://purl.obolibrary.org/obo/GO_0050357 GO:0050354 biolink:MolecularActivity triokinase activity Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+). KEGG_REACTION:R01059|RHEA:13941|Reactome:R-HSA-70349|MetaCyc:TRIOKINASE-RXN|EC:2.7.1.28 go-plus.json ATP:D-glyceraldehyde 3-phosphotransferase activity|triose kinase activity|D-triokinase activity|trio triose kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0050354 GO:0050355 biolink:MolecularActivity triphosphatase activity Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate. KEGG_REACTION:R00138|EC:3.6.1.25|MetaCyc:TRIPHOSPHATASE-RXN|RHEA:14157 go-plus.json inorganic triphosphatase activity|tripolyphosphatase activity|triphosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050355 CHEBI:144422 biolink:ChemicalSubstance N-acetyl-alpha-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144422 chebi_ph7_3 GO:0050358 biolink:MolecularActivity tropinone reductase activity Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone. KEGG_REACTION:R06734|RHEA:24244|EC:1.1.1.236|MetaCyc:TROPINONE-REDUCTASE-RXN go-plus.json tropinone (psi-tropine-forming) reductase activity|pseudotropine:NADP+ 3-oxidoreductase activity|tropinone reductase II activity|pseudotropine forming tropinone reductase activity http://purl.obolibrary.org/obo/GO_0050358 GO:0050359 biolink:MolecularActivity tropomyosin kinase activity Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin. EC:2.7.11.28|MetaCyc:TROPOMYOSIN-KINASE-RXN go-plus.json ATP:tropomyosin O-phosphotransferase activity|STK|tropomyosin kinase (phosphorylating) activity http://purl.obolibrary.org/obo/GO_0050359 CHEBI:37092 biolink:ChemicalSubstance 2'-deoxycytidine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37092 CHEBI:86087 biolink:ChemicalSubstance 4beta,24S-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86087 chebi_ph7_3 GO:0015986 biolink:BiologicalProcess ATP synthesis coupled proton transport The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. go-plus.json chemiosmosis http://purl.obolibrary.org/obo/GO_0015986 GO:0015987 biolink:BiologicalProcess GTP synthesis coupled proton transport The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0015987 GO:0015988 biolink:BiologicalProcess energy coupled proton transmembrane transport, against electrochemical gradient The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport. go-plus.json http://purl.obolibrary.org/obo/GO_0015988 GO:0015989 biolink:BiologicalProcess light-driven proton transport The transport of protons against an electrochemical gradient, using energy from light. go-plus.json http://purl.obolibrary.org/obo/GO_0015989 GO:0015982 biolink:BiologicalProcess obsolete antiport OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction. go-plus.json antiport http://purl.obolibrary.org/obo/GO_0015982 GO:0015983 biolink:BiologicalProcess obsolete symport OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction. go-plus.json symport http://purl.obolibrary.org/obo/GO_0015983 GO:0015984 biolink:BiologicalProcess obsolete uniport OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion. go-plus.json uniport http://purl.obolibrary.org/obo/GO_0015984 GO:0015985 biolink:BiologicalProcess energy coupled proton transport, down electrochemical gradient The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP. go-plus.json http://purl.obolibrary.org/obo/GO_0015985 CHEBI:37086 biolink:ChemicalSubstance C-nucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_37086 GO:0015980 biolink:BiologicalProcess energy derivation by oxidation of organic compounds The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. go-plus.json chemoorganotrophy http://purl.obolibrary.org/obo/GO_0015980 CHEBI:37084 biolink:ChemicalSubstance 3-hydroxyisovaleric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37084 GO:0015981 biolink:BiologicalProcess obsolete passive proton transport, down the electrochemical gradient OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low. go-plus.json passive proton transport, down the electrochemical gradient http://purl.obolibrary.org/obo/GO_0015981 GO:0050352 biolink:MolecularActivity trimethylamine-oxide aldolase activity Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde. KEGG_REACTION:R02512|EC:4.1.2.32|UM-BBD_reactionID:r1409|MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN|RHEA:20217 go-plus.json trimethylamine-N-oxide formaldehyde-lyase activity|trimethylamine N-oxide demethylase activity|trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)|trimethylamine N-oxide formaldehyde-lyase activity|trimethylamine N-oxide aldolase activity http://purl.obolibrary.org/obo/GO_0050352 GO:0050353 biolink:MolecularActivity trimethyllysine dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate. MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN|KEGG_REACTION:R03451|RHEA:14181|EC:1.14.11.8|Reactome:R-HSA-71241 go-plus.json TMLD activity|epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity|6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|TML dioxygenase activity|N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|trimethyllysine,2-oxoglutarate dioxygenase activity|trimethyllysine alpha-ketoglutarate dioxygenase activity|TML hydroxylase activity|TML-alpha-ketoglutarate dioxygenase activity http://purl.obolibrary.org/obo/GO_0050353 GO:0050350 biolink:MolecularActivity trihydroxystilbene synthase activity Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2. EC:2.3.1.95|MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN|RHEA:11936 go-plus.json stilbene synthase activity|malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|resveratrol synthase activity http://purl.obolibrary.org/obo/GO_0050350 CHEBI:37088 biolink:ChemicalSubstance anthrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37088 GO:0050351 biolink:MolecularActivity trimetaphosphatase activity Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate. MetaCyc:TRIMETAPHOSPHATASE-RXN|RHEA:11088|EC:3.6.1.2|KEGG_REACTION:R02504 go-plus.json trimetaphosphate hydrolase activity|inorganic trimetaphosphatase activity http://purl.obolibrary.org/obo/GO_0050351 CHEBI:37089 biolink:ChemicalSubstance ortho-fused tricyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_37089 GO:0050367 biolink:MolecularActivity tyrosine-arginine ligase activity Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+). KEGG_REACTION:R00735|EC:6.3.2.24|MetaCyc:TYROSINE--ARGININE-LIGASE-RXN|RHEA:15345 go-plus.json kyotorphin synthetase activity|L-tyrosine:L-arginine ligase (AMP-forming)|kyotorphin-synthesizing enzyme activity|kyotorphin synthase activity|tyrosyl-arginine synthase activity http://purl.obolibrary.org/obo/GO_0050367 GO:0001312 biolink:BiologicalProcess obsolete replication of extrachromosomal rDNA circles involved in replicative cell aging OBSOLETE. Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication. go-plus.json replication of extrachromosomal rDNA circles during replicative cell aging|replication of extrachromosomal rDNA circles during replicative cell ageing|replication of extrachromosomal ribosomal DNA circles during replicative cell aging http://purl.obolibrary.org/obo/GO_0001312 GO:0050368 biolink:MolecularActivity tyrosine 2,3-aminomutase activity Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate. MetaCyc:TYROSINE-23-AMINOMUTASE-RXN|KEGG_REACTION:R00739|EC:5.4.3.6|RHEA:15781 go-plus.json L-tyrosine 2,3-aminomutase activity|tyrosine alpha,beta-mutase activity http://purl.obolibrary.org/obo/GO_0050368 GO:0001313 biolink:BiologicalProcess obsolete formation of extrachromosomal circular DNA involved in replicative cell aging OBSOLETE. Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age. go-plus.json assembly of extrachromosomal circular DNA involved in replicative cell aging|formation of extrachromosomal circular DNA during replicative cell ageing|formation of extrachromosomal circular DNA during replicative cell aging http://purl.obolibrary.org/obo/GO_0001313 GO:0050365 biolink:MolecularActivity tryptophanamidase activity Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+). MetaCyc:TRYPTOPHANAMIDASE-RXN|EC:3.5.1.57|KEGG_REACTION:R00682|RHEA:11012 go-plus.json L-tryptophanamide amidohydrolase activity|tryptophan aminopeptidase|L-tryptophan aminopeptidase http://purl.obolibrary.org/obo/GO_0050365 GO:0001314 biolink:BiologicalProcess obsolete replication of extrachromosomal circular DNA involved in replicative cell aging OBSOLETE. Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication. go-plus.json replication of extrachromosomal circular DNA during replicative cell ageing|replication of extrachromosomal circular DNA during replicative cell aging http://purl.obolibrary.org/obo/GO_0001314 GO:0050366 biolink:MolecularActivity tyramine N-feruloyltransferase activity Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine. EC:2.3.1.110|MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN|RHEA:19685 go-plus.json feruloyl-CoA tyramine N-feruloyl-CoA transferase activity|tyramine N-feruloyl-CoA transferase activity|feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity|tyramine feruloyltransferase activity|feruloyltyramine synthase activity http://purl.obolibrary.org/obo/GO_0050366 GO:0001315 biolink:BiologicalProcess age-dependent response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. go-plus.json age-dependent response to ROI|age-dependent response to AOS|age-dependent response to reactive oxidative species|age-dependent response to reactive oxygen intermediate|age-dependent response to ROS|age-dependent response to active oxygen species http://purl.obolibrary.org/obo/GO_0001315 CHEBI:144413 biolink:ChemicalSubstance Phospho-anandamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144413 GO:0001310 biolink:BiologicalProcess obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication. go-plus.json extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|extrachromosomal rDNA circle accumulation during replicative cell ageing|extrachromosomal rDNA circle accumulation during replicative cell aging http://purl.obolibrary.org/obo/GO_0001310 GO:0050369 biolink:MolecularActivity [tyrosine 3-monooxygenase] kinase activity Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]. EC:2.7.11.6|MetaCyc:2.7.11.6-RXN|RHEA:17133 go-plus.json STK4|tyrosine 3-monooxygenase kinase (phosphorylating) activity|ATP:tyrosine-3-monoxygenase phosphotransferase activity|pheochromocytoma tyrosine hydroxylase-associated kinase activity|tyrosine 3-monooxygenase kinase activity http://purl.obolibrary.org/obo/GO_0050369 GO:0001311 biolink:BiologicalProcess obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age. go-plus.json assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging|formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging|formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging|formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing http://purl.obolibrary.org/obo/GO_0001311 GO:0015957 biolink:BiologicalProcess bis(5'-nucleosidyl) oligophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. go-plus.json bis(5'-nucleosidyl) oligophosphate biosynthesis|bis(5'-nucleosidyl) oligophosphate anabolism|bis(5'-nucleosidyl) oligophosphate synthesis|bis(5'-nucleosidyl) oligophosphate formation http://purl.obolibrary.org/obo/GO_0015957 GO:0015958 biolink:BiologicalProcess bis(5'-nucleosidyl) oligophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. go-plus.json bis(5'-nucleosidyl) oligophosphate breakdown|bis(5'-nucleosidyl) oligophosphate catabolism|bis(5'-nucleosidyl) oligophosphate degradation http://purl.obolibrary.org/obo/GO_0015958 GO:0015959 biolink:BiologicalProcess diadenosine polyphosphate metabolic process The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. go-plus.json diadenosine polyphosphate metabolism http://purl.obolibrary.org/obo/GO_0015959 GO:0015953 biolink:BiologicalProcess pyrimidine nucleotide interconversion The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0015953 GO:0015954 biolink:BiologicalProcess pyrimidine ribonucleotide interconversion The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0015954 GO:0015955 biolink:BiologicalProcess pyrimidine deoxyribonucleotide interconversion The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0015955 CHEBI:37059 biolink:ChemicalSubstance purine nucleoside tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37059 GO:0015956 biolink:BiologicalProcess bis(5'-nucleosidyl) oligophosphate metabolic process The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. go-plus.json bis(5'-nucleosidyl) oligophosphate metabolism http://purl.obolibrary.org/obo/GO_0015956 GO:0015950 biolink:BiologicalProcess purine nucleotide interconversion The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0015950 GO:0015951 biolink:BiologicalProcess purine ribonucleotide interconversion The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0015951 GO:0015952 biolink:BiologicalProcess purine deoxyribonucleotide interconversion The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0015952 GO:0050360 biolink:MolecularActivity tryptophan 2'-dioxygenase activity Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3. EC:1.13.99.3|RHEA:22620|MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN go-plus.json tryptophan side-chain oxidase activity|tryptophan side-chain alpha,beta-oxidase activity|TSO activity|tryptophan side chain oxidase activity|TSO I|tryptophan side chain oxidase type I|indolyl-3-alkan alpha-hydroxylase activity|TSO II|indole-3-alkane alpha-hydroxylase activity|tryptophan side chain oxidase II|L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving) http://purl.obolibrary.org/obo/GO_0050360 CHEBI:37054 biolink:ChemicalSubstance 3-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37054 chebi_ph7_3 CHEBI:37051 biolink:ChemicalSubstance 3-hydroxy-2-methylbutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37051 CHEBI:37052 biolink:ChemicalSubstance (2S,3S)-3-hydroxy-2-methylbutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37052 GO:0001316 biolink:BiologicalProcess obsolete age-dependent response to reactive oxygen species involved in replicative cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. go-plus.json age-dependent response to reactive oxygen species during replicative cell aging|age-dependent response to ROI during replicative cell aging|age-dependent response to AOS during replicative cell aging|age-dependent response to reactive oxygen species during replicative cell ageing|age-dependent response to reactive oxidative species during replicative cell aging|age-dependent response to reactive oxygen intermediate during replicative cell aging|age-dependent response to active oxygen species during replicative cell aging|age-dependent response to ROS during replicative cell aging http://purl.obolibrary.org/obo/GO_0001316 GO:0050363 biolink:MolecularActivity tryptophan dehydrogenase activity Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+. EC:1.4.1.19|MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN go-plus.json L-tryptophan dehydrogenase activity|TrpDH activity|L-Trp-dehydrogenase activity|TDH|NAD(P)+-L-tryptophan dehydrogenase activity|L-tryptophan:NAD(P)+ oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0050363 GO:0050364 biolink:MolecularActivity tryptophan dimethylallyltransferase activity Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan. MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN|EC:2.5.1.34|RHEA:14173 go-plus.json DMAT synthetase activity|4-(gamma,gamma-dimethylallyl)tryptophan synthase activity|dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity|dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity|dimethylallyltryptophan synthetase activity|dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity http://purl.obolibrary.org/obo/GO_0050364 GO:0001317 biolink:BiologicalProcess obsolete accumulation of oxidatively modified proteins involved in replicative cell aging OBSOLETE. Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking. go-plus.json accumulation of oxidatively modified proteins during replicative cell ageing|accumulation of oxidatively modified proteins during replicative cell aging http://purl.obolibrary.org/obo/GO_0001317 CHEBI:37058 biolink:ChemicalSubstance ribonucleoside tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37058 GO:0050361 biolink:MolecularActivity tryptophan 2-monooxygenase activity Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide. EC:1.13.12.3|KEGG_REACTION:R00679|MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN|RHEA:16165 go-plus.json L-tryptophan:oxygen 2-oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0050361 GO:0001318 biolink:BiologicalProcess obsolete formation of oxidatively modified proteins involved in replicative cell aging OBSOLETE. Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking. go-plus.json formation of oxidatively modified proteins during replicative cell aging|formation of oxidatively modified proteins during replicative cell ageing http://purl.obolibrary.org/obo/GO_0001318 GO:0050362 biolink:MolecularActivity L-tryptophan:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate. EC:2.6.1.27|MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN|RHEA:14093 go-plus.json L-tryptophan transaminase activity|tryptophan transaminase activity|tryptophan aminotransferase activity|5-hydroxytryptophan-ketoglutaric transaminase activity|L-tryptophan aminotransferase activity|L-phenylalanine-2-oxoglutarate aminotransferase activity|hydroxytryptophan aminotransferase activity http://purl.obolibrary.org/obo/GO_0050362 GO:0001319 biolink:BiologicalProcess obsolete inheritance of oxidatively modified proteins involved in replicative cell aging OBSOLETE. A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells. go-plus.json inheritance of oxidatively modified proteins during replicative cell ageing|inheritance of oxidatively modified proteins during replicative cell aging http://purl.obolibrary.org/obo/GO_0001319 CHEBI:37056 biolink:ChemicalSubstance nucleoside tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37056 GO:0050378 biolink:MolecularActivity UDP-glucuronate 4-epimerase activity Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate. MetaCyc:PWY-4861|EC:5.1.3.6|KEGG_REACTION:R01385|MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN|RHEA:11404 go-plus.json UDP-galacturonate 4-epimerase activity|UDP-D-galacturonic acid 4-epimerase activity|uridine diphosphoglucuronate epimerase activity|uridine diphosphoglucuronic epimerase activity|UDP glucuronic epimerase activity|uridine diphospho-D-galacturonic acid|UDPglucuronate 4-epimerase activity http://purl.obolibrary.org/obo/GO_0050378 GO:0001323 biolink:BiologicalProcess obsolete age-dependent general metabolic decline involved in chronological cell aging OBSOLETE. A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function. go-plus.json age-dependent general metabolic decline during chronological cell ageing|age-dependent general metabolic decline during chronological cell aging http://purl.obolibrary.org/obo/GO_0001323 GO:0001324 biolink:BiologicalProcess obsolete age-dependent response to oxidative stress involved in chronological cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism. go-plus.json age-dependent response to oxidative stress during chronological cell aging|age-dependent response to oxidative stress during chronological cell ageing http://purl.obolibrary.org/obo/GO_0001324 GO:0050379 biolink:MolecularActivity UDP-glucuronate 5'-epimerase activity Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate. KEGG_REACTION:R01387|Reactome:R-HSA-2076371|MetaCyc:UDP-GLUCURONATE-5-EPIMERASE-RXN|Reactome:R-HSA-2024100 go-plus.json UDPglucuronate 5'-epimerase activity|UDP-glucuronic acid epimerase activity|C-5-uronosyl epimerase activity|UDP-glucuronate 5' epimerase activity|UDP-glucuronic acid 5'-epimerase activity|uridine diphosphoglucuronate 5'-epimerase activity http://purl.obolibrary.org/obo/GO_0050379 GO:0050376 biolink:MolecularActivity UDP-glucosamine 4-epimerase activity Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine. MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN|RHEA:23492|EC:5.1.3.16 go-plus.json UDPglucosamine 4-epimerase activity|UDP-glucosamine epimerase activity http://purl.obolibrary.org/obo/GO_0050376 GO:0001325 biolink:BiologicalProcess formation of extrachromosomal circular DNA Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats. go-plus.json assembly of extrachromosomal circular DNA http://purl.obolibrary.org/obo/GO_0001325 GO:0050377 biolink:MolecularActivity UDP-glucose 4,6-dehydratase activity Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose. EC:4.2.1.76|RHEA:21500|MetaCyc:UDP-GLUCOSE-46-DEHYDRATASE-RXN|KEGG_REACTION:R00293 go-plus.json UDPglucose 4,6-dehydratase activity|UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)|UDPglucose 4,6-hydro-lyase activity|UDP-D-glucose-4,6-hydrolyase activity|UDP-D-glucose oxidoreductase activity|UDP-glucose 4,6-hydro-lyase activity http://purl.obolibrary.org/obo/GO_0050377 GO:0001326 biolink:BiologicalProcess replication of extrachromosomal circular DNA Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication. go-plus.json http://purl.obolibrary.org/obo/GO_0001326 GO:0001320 biolink:BiologicalProcess obsolete age-dependent response to reactive oxygen species involved in chronological cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. go-plus.json age-dependent response to AOS during chronological cell aging|age-dependent response to reactive oxidative species during chronological cell aging|age-dependent response to reactive oxygen intermediate during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell ageing|age-dependent response to ROS during chronological cell aging|age-dependent response to active oxygen species during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell aging|age-dependent response to ROI during chronological cell aging http://purl.obolibrary.org/obo/GO_0001320 GO:0001321 biolink:BiologicalProcess obsolete age-dependent general metabolic decline involved in replicative cell aging OBSOLETE. A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function. go-plus.json age-dependent general metabolic decline involved in replicative cell aging|age-dependent general metabolic decline during replicative cell ageing http://purl.obolibrary.org/obo/GO_0001321 CHEBI:37070 biolink:ChemicalSubstance 2-methylbutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37070 GO:0001322 biolink:BiologicalProcess obsolete age-dependent response to oxidative stress involved in replicative cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism. go-plus.json age-dependent response to oxidative stress during replicative cell ageing|age-dependent response to oxidative stress during replicative cell aging http://purl.obolibrary.org/obo/GO_0001322 GO:0015968 biolink:BiologicalProcess stringent response A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation. Wikipedia:Stringent_response go-plus.json http://purl.obolibrary.org/obo/GO_0015968 GO:0015969 biolink:BiologicalProcess guanosine tetraphosphate metabolic process The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. MetaCyc:PPGPPMET-PWY go-plus.json guanosine tetraphosphate (5'-ppGpp-3') metabolic process|guanosine tetraphosphate (5'-ppGpp-3') metabolism|guanosine tetraphosphate metabolism http://purl.obolibrary.org/obo/GO_0015969 GO:0015964 biolink:BiologicalProcess diadenosine triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached. go-plus.json diadenosine triphosphate degradation|diadenosine triphosphate breakdown|diadenosine triphosphate catabolism http://purl.obolibrary.org/obo/GO_0015964 GO:0015965 biolink:BiologicalProcess diadenosine tetraphosphate metabolic process The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached. go-plus.json diadenosine tetraphosphate metabolism http://purl.obolibrary.org/obo/GO_0015965 GO:0015966 biolink:BiologicalProcess diadenosine tetraphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached. go-plus.json diadenosine tetraphosphate anabolism|diadenosine tetraphosphate synthesis|diadenosine tetraphosphate formation|diadenosine tetraphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0015966 GO:0015967 biolink:BiologicalProcess diadenosine tetraphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached. go-plus.json diadenosine tetraphosphate catabolism|diadenosine tetraphosphate degradation|diadenosine tetraphosphate breakdown http://purl.obolibrary.org/obo/GO_0015967 GO:0015960 biolink:BiologicalProcess diadenosine polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. go-plus.json diadenosine polyphosphate anabolism|diadenosine polyphosphate synthesis|diadenosine polyphosphate biosynthesis|diadenosine polyphosphate formation http://purl.obolibrary.org/obo/GO_0015960 GO:0015961 biolink:BiologicalProcess diadenosine polyphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. go-plus.json diadenosine polyphosphate catabolism|diadenosine polyphosphate degradation|diadenosine polyphosphate breakdown http://purl.obolibrary.org/obo/GO_0015961 GO:0015962 biolink:BiologicalProcess diadenosine triphosphate metabolic process The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached. go-plus.json diadenosine triphosphate metabolism http://purl.obolibrary.org/obo/GO_0015962 GO:0015963 biolink:BiologicalProcess diadenosine triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached. go-plus.json diadenosine triphosphate biosynthesis|diadenosine triphosphate anabolism|diadenosine triphosphate synthesis|diadenosine triphosphate formation http://purl.obolibrary.org/obo/GO_0015963 GO:0050370 biolink:MolecularActivity tyrosine N-monooxygenase activity Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O. RHEA:22464|MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN go-plus.json CYP79A1 activity|tyrosine N-hydroxylase activity|L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating) http://purl.obolibrary.org/obo/GO_0050370 GO:0050371 biolink:MolecularActivity tyrosine phenol-lyase activity Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate. MetaCyc:TYROSINE-PHENOL-LYASE-RXN|KEGG_REACTION:R00728|EC:4.1.99.2|RHEA:21704 go-plus.json beta-tyrosinase activity|L-tyrosine phenol-lyase (deaminating; pyruvate-forming)|L-tyrosine phenol-lyase (deaminating) http://purl.obolibrary.org/obo/GO_0050371 CHEBI:52684 biolink:ChemicalSubstance butanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52684 CHEBI:37063 biolink:ChemicalSubstance purine ribonucleoside tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37063 GO:0050374 biolink:MolecularActivity UDP-galacturonate decarboxylase activity Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose. RHEA:19725|EC:4.1.1.67|KEGG_REACTION:R02636|MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN go-plus.json UDP-D-galacturonate carboxy-lyase activity|UDPgalacturonate decarboxylase activity|UDP-galacturonic acid decarboxylase activity|UDPGalUA carboxy lyase activity|UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming) http://purl.obolibrary.org/obo/GO_0050374 CHEBI:52680 biolink:ChemicalSubstance 5-(pentadeca-8,11,14-trien-1-yl)resorcinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52680 chebi_ph7_3 GO:0050375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050375 CHEBI:52681 biolink:ChemicalSubstance 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_52681 chebi_ph7_3 GO:0050372 biolink:MolecularActivity ubiquitin-calmodulin ligase activity Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin. MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN go-plus.json ubiquityl-calmodulin synthetase activity|calmodulin:ubiquitin ligase (AMP-forming)|ubiquityl-calmodulin synthase activity|uCaM-synthetase activity|ubiquitin-calmodulin synthetase activity http://purl.obolibrary.org/obo/GO_0050372 GO:0050373 biolink:MolecularActivity UDP-arabinose 4-epimerase activity Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose. KEGG_REACTION:R01473|RHEA:11320|EC:5.1.3.5|MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN go-plus.json UDParabinose 4-epimerase activity|UDP-D-xylose 4-epimerase activity|uridine 5'-diphosphate-D-xylose 4-epimerase activity|UDP-L-arabinose 4-epimerase activity|UDP-D-xylose-4-epimerase activity|UDP arabinose epimerase activity|uridine diphosphoarabinose epimerase activity http://purl.obolibrary.org/obo/GO_0050373 CHEBI:52682 biolink:ChemicalSubstance butane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52682 chebi_ph7_3 CHEBI:37067 biolink:ChemicalSubstance purine ribonucleoside 5'-tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37067 GO:1990475 biolink:CellularComponent synaptic vesicle, recycling pool A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state. go-plus.json recycling pool of synaptic vesicles http://purl.obolibrary.org/obo/GO_1990475 CHEBI:76647 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z)-icosatetraenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76647 chebi_ph7_3 GO:1990476 biolink:CellularComponent synaptic vesicle, resting pool A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool. go-plus.json resting pool of synaptic vesicles|reserve pool of synaptic vesicles http://purl.obolibrary.org/obo/GO_1990476 GO:1990477 biolink:CellularComponent MTREC complex Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex. go-plus.json NURS complex|Mtl1-Red1 core complex|PAXT complex http://purl.obolibrary.org/obo/GO_1990477 CHEBI:76645 biolink:ChemicalSubstance 20-oxoarachidonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76645 chebi_ph7_3 GO:1990478 biolink:BiologicalProcess response to ultrasound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990478 CHEBI:76646 biolink:ChemicalSubstance (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76646 GO:1990471 biolink:MolecularActivity piRNA uni-strand cluster binding Binding to uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa. go-plus.json http://purl.obolibrary.org/obo/GO_1990471 GO:1990472 biolink:MolecularActivity piRNA dual-strand cluster binding Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription. go-plus.json http://purl.obolibrary.org/obo/GO_1990472 GO:1990473 biolink:MolecularActivity ciliary targeting signal binding Binding to a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane. go-plus.json CTS binding http://purl.obolibrary.org/obo/GO_1990473 GO:1990474 biolink:CellularComponent synaptic vesicle, readily releasable pool A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton. go-plus.json readily releasable pool of synaptic vesicles|RRP http://purl.obolibrary.org/obo/GO_1990474 GO:1990470 biolink:MolecularActivity piRNA cluster binding Binding to piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs). go-plus.json http://purl.obolibrary.org/obo/GO_1990470 CHEBI:62002 biolink:ChemicalSubstance galactosyl-(glucosyl)2-(heptosyl)3-(KDO)2-lipid A-bisphosphate(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62002 chebi_ph7_3 CHEBI:62003 biolink:ChemicalSubstance galactosyl-(glucosyl)3-(heptosyl)3-(KDO)2-lipid A-bisphosphate(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62003 chebi_ph7_3 CHEBI:62000 biolink:ChemicalSubstance glucosyl-heptosyl-(phosphonatoheptosyl)2-(KDO)2-lipid A(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62000 chebi_ph7_3 CHEBI:62001 biolink:ChemicalSubstance galactosyl-glucosyl-heptosyl-(phosphonatoheptosyl)2-(KDO)2-lipid A(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62001 chebi_ph7_3 CHEBI:62006 biolink:ChemicalSubstance maltopentaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62006 chebi_ph7_3 CHEBI:62007 biolink:ChemicalSubstance maltohexaose hexasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62007 CHEBI:62004 biolink:ChemicalSubstance lipid A-core(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62004 chebi_ph7_3 CHEBI:62009 biolink:ChemicalSubstance maltoheptaose heptasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62009 CHEBI:76640 biolink:ChemicalSubstance (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76640 CL:0000081 biolink:Cell blood cell A cell found predominately in the blood. go-plus.json http://purl.obolibrary.org/obo/CL_0000081 GO:1990479 biolink:BiologicalProcess obsolete response to lipoic acid OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus. go-plus.json response to 5-(1,2-dithiolan-3-yl)pentanoic acid http://purl.obolibrary.org/obo/GO_1990479 CL:0000082 biolink:Cell epithelial cell of lung An epithelial cell of the lung. go-plus.json lung epithelial cell http://purl.obolibrary.org/obo/CL_0000082 CHEBI:76643 biolink:ChemicalSubstance (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76643 CL:0000083 biolink:Cell epithelial cell of pancreas An epithelial cell of the pancreas. go-plus.json pancreas epithelial cell|pancreatic epithelial cell http://purl.obolibrary.org/obo/CL_0000083 CHEBI:76644 biolink:ChemicalSubstance (3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76644 CL:0000084 biolink:Cell T cell A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. go-plus.json T-lymphocyte|T lymphocyte|mature T cell|immature T cell|T-cell http://purl.obolibrary.org/obo/CL_0000084 CHEBI:76641 biolink:ChemicalSubstance (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76641 CHEBI:76642 biolink:ChemicalSubstance (3R,7Z,10Z,13Z,16Z,19Z)-3-hydroxydocosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76642 CHEBI:76658 biolink:ChemicalSubstance (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76658 GO:1990486 biolink:BiologicalProcess anaerobic fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. go-plus.json anaerobic fatty acid degradation http://purl.obolibrary.org/obo/GO_1990486 GO:1990487 biolink:BiologicalProcess anaerobic lignin catabolic process The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units. go-plus.json anaerobic lignin degradation http://purl.obolibrary.org/obo/GO_1990487 CHEBI:76659 biolink:ChemicalSubstance (3R,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76659 GO:1990488 biolink:BiologicalProcess anaerobic cellulose catabolic process The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen. go-plus.json anaerobic cellulose degradation http://purl.obolibrary.org/obo/GO_1990488 CHEBI:76656 biolink:ChemicalSubstance (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76656 GO:1990489 biolink:BiologicalProcess anaerobic pectin catabolic process The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen. go-plus.json anaerobic pectin degradation http://purl.obolibrary.org/obo/GO_1990489 CHEBI:76657 biolink:ChemicalSubstance (3R,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76657 GO:1990482 biolink:MolecularActivity sphingolipid alpha-glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC. go-plus.json inositol phosphorylceramide glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_1990482 GO:1990483 biolink:CellularComponent Clr6 histone deacetylase complex I'' A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3. go-plus.json http://purl.obolibrary.org/obo/GO_1990483 GO:1990484 biolink:BiologicalProcess aerobic lactate catabolic process The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen. go-plus.json aerobic lactic acid catabolic process http://purl.obolibrary.org/obo/GO_1990484 GO:1990485 biolink:BiologicalProcess anaerobic lactate catabolic process The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen. go-plus.json anaerobic lactic acid catabolic process http://purl.obolibrary.org/obo/GO_1990485 CHEBI:62010 biolink:ChemicalSubstance maltoheptaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62010 chebi_ph7_3 GO:1990480 biolink:MolecularActivity obsolete geranyl diphosphate synthase OBSOLETE. Catalyzes the condensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_1990480 GO:1990481 biolink:BiologicalProcess mRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in an mRNA molecule. go-plus.json mRNA pseudouridylation http://purl.obolibrary.org/obo/GO_1990481 CHEBI:62013 biolink:ChemicalSubstance glycerol 1-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62013 CHEBI:62014 biolink:ChemicalSubstance cis-tetradec-3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_62014 CHEBI:62011 biolink:ChemicalSubstance 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_62011 CHEBI:62012 biolink:ChemicalSubstance 5-deoxy-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62012 chebi_ph7_3 CHEBI:62017 biolink:ChemicalSubstance glucosyl-heptosyl-4-phosphoheptosyl-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_62017 CL:0000097 biolink:Cell mast cell A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. go-plus.json histaminocyte|mastocyte|labrocyte|tissue basophil http://purl.obolibrary.org/obo/CL_0000097 CL:0000098 biolink:Cell sensory epithelial cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. go-plus.json neuroepithelial cell http://purl.obolibrary.org/obo/CL_0000098 CHEBI:62015 biolink:ChemicalSubstance L-Ala-gamma-D-Glu-meso-Dap-D-Ala go-plus.json http://purl.obolibrary.org/obo/CHEBI_62015 CL:0000099 biolink:Cell interneuron Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. go-plus.json http://purl.obolibrary.org/obo/CL_0000099 CHEBI:62016 biolink:ChemicalSubstance glucosyl-(heptosyl)2-(KDO)2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_62016 CHEBI:76650 biolink:ChemicalSubstance (3R,11Z,14Z,17Z,20Z,23Z)-3-hydroxyhexacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76650 CHEBI:76651 biolink:ChemicalSubstance (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76651 CL:0000092 biolink:Cell osteoclast A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. go-plus.json chondroclast http://purl.obolibrary.org/obo/CL_0000092 CHEBI:76654 biolink:ChemicalSubstance (3R,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76654 NCBITaxon:2696291 biolink:OrganismalEntity Ochrophyta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2696291 CL:0000094 biolink:Cell granulocyte A leukocyte with abundant granules in the cytoplasm. go-plus.json polymorphonuclear leukocyte|granular leucocyte|granular leukocyte http://purl.obolibrary.org/obo/CL_0000094 CHEBI:76655 biolink:ChemicalSubstance EC 2.1.* (C1-transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76655 CL:0000095 biolink:Cell neuron associated cell go-plus.json http://purl.obolibrary.org/obo/CL_0000095 CHEBI:76652 biolink:ChemicalSubstance (3R,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76652 CHEBI:76653 biolink:ChemicalSubstance (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76653 CL:0000096 biolink:Cell mature neutrophil A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. go-plus.json poly|polynuclear neutrophilic leucocyte|polymorphonuclear neutrophil|polymorphonuclear leucocyte|polynuclear neutrophilic leukocyte|mature neutrophil leucocyte|mature neutrocyte|PMN|polymorphonuclear leukocyte|mature neutrophilic leucocyte|mature neutrophil leukocyte|mature neutrophilic leukocyte http://purl.obolibrary.org/obo/CL_0000096 GO:1990497 biolink:BiologicalProcess regulation of cytoplasmic translation in response to stress Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_1990497 CHEBI:76669 biolink:ChemicalSubstance (3R,23Z,26Z,29Z,32Z,35Z)-3-hydroxyoctatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76669 GO:1990498 biolink:CellularComponent mitotic spindle microtubule Any microtubule that is part of a mitotic spindle; anchored at one spindle pole. go-plus.json http://purl.obolibrary.org/obo/GO_1990498 GO:1990499 biolink:CellularComponent raps-insc complex Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2). go-plus.json Rapsynoid-Inscuteable complex|partner of inscuteable-inscuteable complex http://purl.obolibrary.org/obo/GO_1990499 CHEBI:76667 biolink:ChemicalSubstance (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76667 CHEBI:76668 biolink:ChemicalSubstance EC 2.7.* (P-containing group transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76668 GO:1990493 biolink:CellularComponent obsolete cyclin H-CDK7 complex OBSOLETE. A protein complex consisting of cyclin H and cyclin-dependent kinase 7 (CDK7). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json cyclin H-CDK7 complex http://purl.obolibrary.org/obo/GO_1990493 GO:1990494 biolink:BiologicalProcess obsolete regulation of mitotic cytokinesis, actomyosin contractile ring assembly OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cytokinesis, actomyosin contractile ring assembly. go-plus.json regulation of mitotic cytokinesis, actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1990494 GO:1990495 biolink:BiologicalProcess obsolete actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly OBSOLETE. An actin filament organization process that contributes to actomyosin contractile ring assembly during mitotic cytokinesis. go-plus.json actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1990495 GO:1990496 biolink:BiologicalProcess obsolete regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly OBSOLETE. An actin filament organization process that contributes to regulation of actomyosin contractile ring assembly during mitotic cytokinesis. go-plus.json regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1990496 GO:1990490 biolink:CellularComponent archaeal proton-transporting A-type ATPase complex A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea. go-plus.json archaeal A-type ATPase protein complex|A-type ATPase protein complex http://purl.obolibrary.org/obo/GO_1990490 GO:1990491 biolink:BiologicalProcess methane biosynthetic process from methanol and hydrogen The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen. go-plus.json methanogenesis from methanol and hydrogen|methane biosynthesis from methanol and hydrogen http://purl.obolibrary.org/obo/GO_1990491 GO:1990492 biolink:BiologicalProcess obsolete mitotic cell cycle checkpoint inhibiting CAR assembly OBSOLETE. A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase. go-plus.json Mad2-dependent mitotic cell cycle checkpoint|mitotic cell cycle checkpoint inhibiting cytokinetic actomyosin ring assembly http://purl.obolibrary.org/obo/GO_1990492 CL:0000064 biolink:Cell ciliated cell A cell that has a filiform extrusion of the cell surface. go-plus.json http://purl.obolibrary.org/obo/CL_0000064 CL:0000066 biolink:Cell epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. go-plus.json epitheliocyte http://purl.obolibrary.org/obo/CL_0000066 CL:0000067 biolink:Cell ciliated epithelial cell An epithelial cell that has a cilia. go-plus.json http://purl.obolibrary.org/obo/CL_0000067 CL:0000068 biolink:Cell duct epithelial cell An epithelial cell that is part of a duct. go-plus.json http://purl.obolibrary.org/obo/CL_0000068 CL:0000069 biolink:Cell branched duct epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000069 CHEBI:76661 biolink:ChemicalSubstance EC 2.3.* (acyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76661 CHEBI:76662 biolink:ChemicalSubstance EC 2.4.* (glycosyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76662 CHEBI:76660 biolink:ChemicalSubstance EC 2.2.* (aldehyde or ketone transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76660 CHEBI:76665 biolink:ChemicalSubstance EC 2.6.* (nitrogenous group transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76665 CL:0000060 biolink:Cell odontoblast Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell. go-plus.json http://purl.obolibrary.org/obo/CL_0000060 CHEBI:76666 biolink:ChemicalSubstance (3R,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76666 CHEBI:76663 biolink:ChemicalSubstance EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76663 CL:0000062 biolink:Cell osteoblast Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell. go-plus.json http://purl.obolibrary.org/obo/CL_0000062 CHEBI:76664 biolink:ChemicalSubstance (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76664 CHEBI:76678 biolink:ChemicalSubstance (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76678 CHEBI:76679 biolink:ChemicalSubstance (3R,12Z,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76679 CHEBI:62031 biolink:ChemicalSubstance polar amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62031 chebi_ph7_3 CL:0000075 biolink:Cell columnar/cuboidal epithelial cell A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. go-plus.json http://purl.obolibrary.org/obo/CL_0000075 CL:0000076 biolink:Cell squamous epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000076 CHEBI:62037 biolink:ChemicalSubstance beta-D-Manp-(1->2)-D-Manp go-plus.json http://purl.obolibrary.org/obo/CHEBI_62037 chebi_ph7_3 CL:0000077 biolink:Cell mesothelial cell A flattened epithelial cell of mesenchymal origin that lines the serous cavity. go-plus.json mesotheliocyte http://purl.obolibrary.org/obo/CL_0000077 CL:0000079 biolink:Cell stratified epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000079 CHEBI:76672 biolink:ChemicalSubstance (3R,8Z,11Z,14Z,17Z,20Z,23Z)-hydroxyhexacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76672 CHEBI:76673 biolink:ChemicalSubstance (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76673 CHEBI:76670 biolink:ChemicalSubstance (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76670 CHEBI:76671 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76671 CL:0000071 biolink:Cell blood vessel endothelial cell An endothelial cell that lines the vasculature. go-plus.json cuboidal endothelial cell of vascular tree http://purl.obolibrary.org/obo/CL_0000071 CHEBI:76675 biolink:ChemicalSubstance (3R,10Z,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76675 GO:1990431 biolink:BiologicalProcess priRNA 3'-end processing The process of forming the mature 3' end of a priRNA molecule. go-plus.json primal small RNA 3'-end processing|priRNA 3' end processing http://purl.obolibrary.org/obo/GO_1990431 GO:1990432 biolink:BiologicalProcess siRNA 3'-end processing The process of forming the mature 3' end of a siRNA molecule. go-plus.json siRNA 3' end processing|small interfering RNA 3'-end processing http://purl.obolibrary.org/obo/GO_1990432 GO:1990433 biolink:CellularComponent CSL-Notch-Mastermind transcription factor complex A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes. go-plus.json CSL-NotchIC-MASTERMIND complex http://purl.obolibrary.org/obo/GO_1990433 GO:1990434 biolink:CellularComponent lower tip-link density An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises. go-plus.json LTLD http://purl.obolibrary.org/obo/GO_1990434 GO:1990430 biolink:MolecularActivity extracellular matrix protein binding Binding to a protein that is part of an extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_1990430 CHEBI:62041 biolink:ChemicalSubstance P(1),P(5)-bis(5'-adenosyl) pentaphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62041 chebi_ph7_3 CHEBI:86013 biolink:ChemicalSubstance 2-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_86013 chebi_ph7_3 CHEBI:62046 biolink:ChemicalSubstance biotinate sulfoxide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62046 chebi_ph7_3 CHEBI:86014 biolink:ChemicalSubstance 3,22-dioxochol-4-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86014 chebi_ph7_3 CHEBI:62047 biolink:ChemicalSubstance (S)-carnitinyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62047 chebi_ph7_3 CHEBI:86016 biolink:ChemicalSubstance GDP-N,N'-diacetylbacillosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86016 chebi_ph7_3 CL:0000042 biolink:Cell neutrophilic myeloblast A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. go-plus.json neutrophilic granuloblast http://purl.obolibrary.org/obo/CL_0000042 CHEBI:86018 biolink:ChemicalSubstance 3beta-hydroxychol-5-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86018 chebi_ph7_3 CL:0000043 biolink:Cell mature basophil A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. go-plus.json mature basophil leucocyte|polymorphonuclear leucocyte|mature basophil leukocyte|polymorphonuclear leukocyte http://purl.obolibrary.org/obo/CL_0000043 CHEBI:86019 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86019 chebi_ph7_3 CHEBI:62048 biolink:ChemicalSubstance haloacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_62048 CHEBI:62049 biolink:ChemicalSubstance acyl donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62049 CL:0000047 biolink:Cell neuronal stem cell Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. go-plus.json NSC|neural stem cell http://purl.obolibrary.org/obo/CL_0000047 CHEBI:76680 biolink:ChemicalSubstance (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76680 CL:0000048 biolink:Cell multi fate stem cell A stem cell that can give rise to multiple lineages of cells. go-plus.json multifate stem cell|multi-fate stem cell|multipotent cell|multipotent stem cell http://purl.obolibrary.org/obo/CL_0000048 CL:0000049 biolink:Cell common myeloid progenitor A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. go-plus.json common myeloid precursor|colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte|CFU-GEMM|CFU-S|pluripotent stem cell (bone marrow)|multipotential myeloid stem cell|myeloid stem cell|CMP http://purl.obolibrary.org/obo/CL_0000049 GO:1990439 biolink:MolecularActivity MAP kinase serine/threonine phosphatase activity Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990439 CHEBI:76683 biolink:ChemicalSubstance (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76683 PR:000000017 biolink:Protein interferon gamma A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions. go-plus.json IFNG|immune interferon|IFN-gamma http://purl.obolibrary.org/obo/PR_000000017 CHEBI:76684 biolink:ChemicalSubstance (3R,16Z,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76684 PR:000000019 biolink:Protein mitogen-activated protein kinase A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. go-plus.json kinase-related transforming protein|MAPK http://purl.obolibrary.org/obo/PR_000000019 CHEBI:76682 biolink:ChemicalSubstance (3R,14Z,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76682 GO:1990435 biolink:CellularComponent upper tip-link density An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends. go-plus.json UTLD http://purl.obolibrary.org/obo/GO_1990435 CHEBI:76687 biolink:ChemicalSubstance (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76687 CHEBI:76688 biolink:ChemicalSubstance (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76688 GO:1990436 biolink:BiologicalProcess obsolete MAPK cascade involved in oxidative stress signaling pathway OBSOLETE. A series of molecular signals in which a MAP kinase cascade activated by oxidative stress relays one or more of the signals, MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. Just FYI in pombe the osmotic stress and oxidative stress MAPK cascade involve many of the same proteins, but the pathways are slightly different, therefore Im req this term. go-plus.json MAPK cascade involved in oxidative stress signaling pathway http://purl.obolibrary.org/obo/GO_1990436 CL:0000040 biolink:Cell monoblast A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. go-plus.json colony forming unit monocyte|CFU-M|colony forming unit macrophage|monocyte stem cell http://purl.obolibrary.org/obo/CL_0000040 GO:1990437 biolink:BiologicalProcess snRNA 2'-O-methylation The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990437 CHEBI:76685 biolink:ChemicalSubstance (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76685 GO:1990438 biolink:BiologicalProcess U6 2'-O-snRNA methylation The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990438 CHEBI:76686 biolink:ChemicalSubstance (3R,18Z,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76686 GO:1990442 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to nitrosative stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. go-plus.json nitrosative stress-induced apoptosis|nitrosative stress-induced intrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1990442 GO:1990443 biolink:BiologicalProcess peptidyl-threonine autophosphorylation The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990443 GO:1990444 biolink:MolecularActivity F-box domain binding Binding to an F-box domain of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990444 GO:1990445 biolink:BiologicalProcess obsolete Multiciliate cell differentiation OBSOLETE. The process in which a relatively unspecialized cell acquires features of a multiciliated cell, a specialized epithelial cell type that extends anywhere from 150 to 200 motile cilia per cell in order to produce a vigorous fluid flow critical to human health in several organ systems. go-plus.json Multiciliate cell differentiation http://purl.obolibrary.org/obo/GO_1990445 GO:1990440 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress. go-plus.json ER stress-induced upregulation of transcription|up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|upregulation of Pol II transcription induced by ER stress|stimulation of transcription from RNA polymerase II promoter in response to ER stress|activation of transcription from RNA polymerase II promoter in response to ER stress|up-regulation of transcription induced by ER stress http://purl.obolibrary.org/obo/GO_1990440 GO:1990441 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress. go-plus.json repression of transcription from RNA polymerase II promoter under ER stress|ER stress-induced negative regulation of transcription from RNA polymerase II promoter|inhibition of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|negative regulation of transcription from RNA polymerase II promoter in response to ER stress|down-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|reduction of transcription from RNA polymerase II promoter under ER stress|suppression of transcription from RNA polymerase II promoter under ER stress http://purl.obolibrary.org/obo/GO_1990441 CHEBI:62055 biolink:ChemicalSubstance deoxy oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62055 CL:0000055 biolink:Cell non-terminally differentiated cell A precursor cell with a limited number of potential fates. go-plus.json blast cell http://purl.obolibrary.org/obo/CL_0000055 CL:0000056 biolink:Cell myoblast A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. go-plus.json http://purl.obolibrary.org/obo/CL_0000056 CL:0000057 biolink:Cell fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. go-plus.json http://purl.obolibrary.org/obo/CL_0000057 CL:0000058 biolink:Cell chondroblast Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. go-plus.json chrondoplast http://purl.obolibrary.org/obo/CL_0000058 CL:0000059 biolink:Cell ameloblast Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. go-plus.json amelocyte|enamel secreting cell http://purl.obolibrary.org/obo/CL_0000059 PR:000000028 biolink:Protein small GTPase A protein with a core domain composition consisting of a Ras family domain (Pfam:PF00071). The small GTPases are monomeric G-proteins which function as GDP/GTP-regulated molecular switches. go-plus.json http://purl.obolibrary.org/obo/PR_000000028 CHEBI:76695 biolink:ChemicalSubstance EC 5.4.* (intramolecular transferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76695 GO:1990446 biolink:MolecularActivity U1 snRNP binding Binding to a U1 small nuclear ribonucleoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_1990446 CL:0000050 biolink:Cell megakaryocyte-erythroid progenitor cell A progenitor cell committed to the megakaryocyte and erythroid lineages. go-plus.json colony forming unit erythroid megakaryocyte|CFU-EM|megakaryocyte/erythroid progenitor cell|MEP|megakaryocyte/erythrocyte progenitor|CFU-MegE|Meg/E progenitor http://purl.obolibrary.org/obo/CL_0000050 GO:1990447 biolink:MolecularActivity U2 snRNP binding Binding to a U2 small nuclear ribonucleoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_1990447 CL:0000051 biolink:Cell common lymphoid progenitor A oligopotent progenitor cell committed to the lymphoid lineage. go-plus.json common lymphocyte precursor|lymphoid stem cell|CLP|ELP|common lymphoid precursor|common lymphocyte progenitor|early lymphocyte progenitor|lymphopoietic stem cell|committed lymphopoietic stem cell http://purl.obolibrary.org/obo/CL_0000051 GO:1990448 biolink:MolecularActivity exon-exon junction complex binding Binding to an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. go-plus.json EJC binding http://purl.obolibrary.org/obo/GO_1990448 GO:1990449 biolink:CellularComponent obsolete amylin receptor OBSOLETE. A G protein-coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP). Amylin is produced in beta-islet cells of the pancreas. It is implicated in selective inhibition of insulin-stimulated glucose utilization and glycogen deposition in muscle, gastric emptying, gastric acid secretion, postprandial glucagon secretion and food intake and aids weight loss. go-plus.json CALCR-RAMP2 receptor|CALCR-RAMP3 receptor|AMY1 receptor|AMY2 receptor|AMY3 receptor|amylin receptor|CALCR-RAMP1 receptor http://purl.obolibrary.org/obo/GO_1990449 CHEBI:76697 biolink:ChemicalSubstance EC 5.99.* (other isomerases) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76697 GO:1990453 biolink:CellularComponent nucleosome disassembly/reassembly complex A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex. go-plus.json eaf5/7/3 complex http://purl.obolibrary.org/obo/GO_1990453 GO:1990454 biolink:CellularComponent L-type voltage-gated calcium channel complex A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation. go-plus.json cardiac muscle L-type voltage-gated calcium channel complex|skeletal muscle L-type voltage-gated calcium channel complex http://purl.obolibrary.org/obo/GO_1990454 GO:1990455 biolink:CellularComponent PTEN phosphatase complex A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function. go-plus.json phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer|phosphatase and tensin homolog|phosphatase and tensin homolog deleted on chromosome ten homodimer http://purl.obolibrary.org/obo/GO_1990455 GO:1990456 biolink:BiologicalProcess mitochondrion-endoplasmic reticulum membrane tethering The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. go-plus.json mitochondrion-endoplasmic reticulum tethering|mitochondrion-ER tethering|mitochondrion-ER membrane tethering|mitochondrion-ER attachment|mitochondrion-endoplasmic reticulum attachment http://purl.obolibrary.org/obo/GO_1990456 GO:1990450 biolink:MolecularActivity linear polyubiquitin binding Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next. go-plus.json M1-linked ubiquitin chain binding http://purl.obolibrary.org/obo/GO_1990450 GO:1990451 biolink:BiologicalProcess cellular stress response to acidic pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json cellular stress response to acidity http://purl.obolibrary.org/obo/GO_1990451 GO:1990452 biolink:CellularComponent Parkin-FBXW7-Cul1 ubiquitin ligase complex A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein. go-plus.json Parkin-HSel-10-Cullin-1 complex|Parkin/Cul1/F-box protein complex|Park2-FBXW7-Cul1 complex|Parkin-FBXW7-Cul1 protein complex|PRKN-FBXW7-Cul1 complex http://purl.obolibrary.org/obo/GO_1990452 CHEBI:62064 biolink:ChemicalSubstance butane-2,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62064 chebi_ph7_3 CL:0000029 biolink:Cell neuron neural crest derived go-plus.json http://purl.obolibrary.org/obo/CL_0000029 CHEBI:62065 biolink:ChemicalSubstance chondroitin 6'-sulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62065 chebi_ph7_3 CHEBI:62069 biolink:ChemicalSubstance phaseic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62069 chebi_ph7_3 CHEBI:86037 biolink:ChemicalSubstance 3beta-hydroxychola-5,22-dien-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86037 chebi_ph7_3 CL:0000020 biolink:Cell spermatogonium An euploid male germ cell of an early stage of spermatogenesis. go-plus.json http://purl.obolibrary.org/obo/CL_0000020 CL:0000021 biolink:Cell female germ cell Female germ cell is a germ cell that supports female gamete production. go-plus.json http://purl.obolibrary.org/obo/CL_0000021 CL:0000022 biolink:Cell female germ line stem cell go-plus.json http://purl.obolibrary.org/obo/CL_0000022 CL:0000023 biolink:Cell oocyte A female germ cell that has entered meiosis. go-plus.json oogonium http://purl.obolibrary.org/obo/CL_0000023 CL:0000024 biolink:Cell oogonial cell An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. go-plus.json http://purl.obolibrary.org/obo/CL_0000024 CL:0000025 biolink:Cell egg cell A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. go-plus.json ovum|mature oocyte http://purl.obolibrary.org/obo/CL_0000025 CL:0000026 biolink:Cell invertebrate nurse cell A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. go-plus.json nurse cell http://purl.obolibrary.org/obo/CL_0000026 CL:0000027 biolink:Cell smooth muscle cell neural crest derived A smooth muscle cell derived from the neural crest. go-plus.json http://purl.obolibrary.org/obo/CL_0000027 GO:1990457 biolink:CellularComponent pexophagosome A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy. go-plus.json http://purl.obolibrary.org/obo/GO_1990457 GO:1990458 biolink:MolecularActivity lipooligosaccharide binding Binding to lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria. go-plus.json LOS binding|endotoxin binding http://purl.obolibrary.org/obo/GO_1990458 GO:1990459 biolink:MolecularActivity transferrin receptor binding Binding to a transferrin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_1990459 GO:1990464 biolink:MolecularActivity D-2-hydroxyacid dehydrogenase (quinone) activity Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol. go-plus.json D-lactate dehydrogenase (quinone) activity|(R)-2-hydroxy acid dehydrogenase activity|D-lactate:quinone oxidoreductase activity|(R)-2-hydroxyacid:quinone oxidoreductase activity|D-lactate dehydrogenase activity|(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_1990464 GO:1990465 biolink:MolecularActivity aldehyde oxygenase (deformylating) activity Catalysis of the reaction a long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+). RHEA:21440|EC:4.1.99.5 go-plus.json http://purl.obolibrary.org/obo/GO_1990465 GO:1990466 biolink:BiologicalProcess protein autosumoylation The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. go-plus.json protein auto-sumoylation|protein self-sumoylation http://purl.obolibrary.org/obo/GO_1990466 GO:1990467 biolink:CellularComponent NuA3a histone acetyltransferase complex A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p. go-plus.json http://purl.obolibrary.org/obo/GO_1990467 GO:1990460 biolink:MolecularActivity leptin receptor binding Binding to a leptin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_1990460 CHEBI:62071 biolink:ChemicalSubstance 2-cis-abscisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62071 chebi_ph7_3 GO:1990461 biolink:BiologicalProcess detoxification of iron ion Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion. go-plus.json http://purl.obolibrary.org/obo/GO_1990461 CHEBI:62072 biolink:ChemicalSubstance naptalamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62072 chebi_ph7_3 GO:1990462 biolink:CellularComponent omegasome Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites. go-plus.json http://purl.obolibrary.org/obo/GO_1990462 GO:1990463 biolink:CellularComponent lateral cortical node A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins. go-plus.json Skb1-containing cortical node http://purl.obolibrary.org/obo/GO_1990463 CHEBI:62070 biolink:ChemicalSubstance nalidixic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62070 chebi_ph7_3 CHEBI:62075 biolink:ChemicalSubstance (S)-3-hydroxyhexanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62075 chebi_ph7_3 CL:0000039 biolink:Cell germ line cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. go-plus.json http://purl.obolibrary.org/obo/CL_0000039 CHEBI:86020 biolink:ChemicalSubstance 20-methyl-3-oxopregna-4,17-dien-21-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86020 chebi_ph7_3 CHEBI:86021 biolink:ChemicalSubstance S-geranylgeranyl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86021 chebi_ph7_3 CHEBI:62074 biolink:ChemicalSubstance 3-chloroacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62074 chebi_ph7_3 CHEBI:86026 biolink:ChemicalSubstance tRNA threonylcarbamoyladenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86026 CHEBI:62077 biolink:ChemicalSubstance trans-hex-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62077 chebi_ph7_3 CHEBI:86027 biolink:ChemicalSubstance naphthopyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_86027 CL:0000031 biolink:Cell neuroblast (sensu Vertebrata) A cell that will develop into a neuron often after a migration phase. go-plus.json neuroblast http://purl.obolibrary.org/obo/CL_0000031 CHEBI:86028 biolink:ChemicalSubstance 17-hydroxy-3-oxopregn-4-en-20-carboxy-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86028 chebi_ph7_3 CHEBI:86029 biolink:ChemicalSubstance liver X receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_86029 CL:0000034 biolink:Cell stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. go-plus.json http://purl.obolibrary.org/obo/CL_0000034 PR:000000001 biolink:Protein protein An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA. go-plus.json http://purl.obolibrary.org/obo/PR_000000001 CL:0000035 biolink:Cell single fate stem cell A stem cell that self-renews as well as give rise to a single mature cell type. go-plus.json unipotential stem cell|unipotent stem cell http://purl.obolibrary.org/obo/CL_0000035 CL:0000036 biolink:Cell epithelial fate stem cell go-plus.json http://purl.obolibrary.org/obo/CL_0000036 CL:0000037 biolink:Cell hematopoietic stem cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. go-plus.json blood forming stem cell|colony forming unit hematopoietic|hemopoietic stem cell|HSC http://purl.obolibrary.org/obo/CL_0000037 CL:0000038 biolink:Cell erythroid progenitor cell A progenitor cell committed to the erythroid lineage. go-plus.json erythroid stem cell|CFU-E|BFU-E|blast forming unit erythroid|colony forming unit erythroid|burst forming unit erythroid http://purl.obolibrary.org/obo/CL_0000038 PR:000000008 biolink:Protein TGF-beta-like cystine-knot cytokine A protein with a core domain composition consisting of a signal peptide, a variable propeptide region and a Transforming growth factor beta like domain (Pfam:PF00019), which is a cystine-knot domain containing four conserved beta strands, S1-S4, which form two antiparallel beta sheets (SI-S2 and S3-S4) interconnected by three disulfide bridges in a knot-like topology. Cystines [II-V] and [III-VI] form a ring through which the remaining disulfide bond (Cys[I-IV]) penetrates. Insertion of different variable regions into this common motif has given rise to various subclasses of the growth factor cystine-knot domain. go-plus.json TGF-beta superfamily http://purl.obolibrary.org/obo/PR_000000008 GO:1990468 biolink:CellularComponent NuA3b histone acetyltransferase complex A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p. go-plus.json http://purl.obolibrary.org/obo/GO_1990468 GO:1990469 biolink:CellularComponent Rhino-Deadlock-Cutoff Complex Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation. go-plus.json RDC complex|rhi-del-cuff complex http://purl.obolibrary.org/obo/GO_1990469 CL:0000030 biolink:Cell glioblast go-plus.json http://purl.obolibrary.org/obo/CL_0000030 GO:1990871 biolink:CellularComponent Vma12-Vma22 assembly complex A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p. go-plus.json http://purl.obolibrary.org/obo/GO_1990871 CHEBI:27636 biolink:ChemicalSubstance L-glycol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27636 chebi_ph7_3 GO:1990872 biolink:BiologicalProcess obsolete negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by negative regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by activation of transcription from RNA polymerase II promoter|negative regulation of sterol import by negative regulation of transcription from Pol II promoter|negative regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by activation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1990872 GO:1990873 biolink:CellularComponent intrinsic component of plasma membrane of cell tip The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip. go-plus.json http://purl.obolibrary.org/obo/GO_1990873 CHEBI:27638 biolink:ChemicalSubstance cobalt atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27638 chebi_ph7_3 GO:1990874 biolink:BiologicalProcess vascular associated smooth muscle cell proliferation The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. go-plus.json vascular smooth muscle cell proliferation|VSMC proliferation http://purl.obolibrary.org/obo/GO_1990874 CHEBI:27639 biolink:ChemicalSubstance (E)-2-benzylidenesuccinyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27639 CHEBI:27632 biolink:ChemicalSubstance acetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27632 chebi_ph7_3 UBERON:0009030 biolink:AnatomicalEntity left pulmonary vein Vein that drains left lung and returns blood to the heart. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009030 GO:1990870 biolink:CellularComponent obsolete protein fibril OBSOLETE. A polymer of proteins that form a fine fiber. go-plus.json http://purl.obolibrary.org/obo/GO_1990870 CHEBI:27630 biolink:ChemicalSubstance precorrin-5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27630 UBERON:0010020 biolink:AnatomicalEntity tubotympanic recess epithelium The dorsal portion of the embryonic first endodermal pharyngeal pouch; it develops into the middle ear cavity. go-plus.json tubotympanic recess http://purl.obolibrary.org/obo/UBERON_0010020 UBERON:0010025 biolink:AnatomicalEntity dorsal part of pharyngeal pouch 3 go-plus.json dorsal branchial pouch 3 endoderm|dorsal wing of pharyngeal pouch 3|dorsal pharyngeal pouch 3 endoderm|cranial dorsal aspect of third dorsal pharyngeal pouch|dorsal 3rd branchial pouch|dorsal 3rd arch pharyngeal pouch endoderm|dorsal pharyngeal pouch 3 http://purl.obolibrary.org/obo/UBERON_0010025 UBERON:0010026 biolink:AnatomicalEntity ventral part of pharyngeal pouch 3 go-plus.json ventral 3rd branchial pouch|ventral 3rd arch pharyngeal pouch endoderm|caudal ventral aspect of third dorsal pharyngeal pouch|ventral pharyngeal pouch 3|ventral branchial pouch 3 endoderm|ventral wing of pharyngeal pouch 3|ventral pharyngeal pouch 3 endoderm http://purl.obolibrary.org/obo/UBERON_0010026 GO:1990879 biolink:CellularComponent CST complex A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection. go-plus.json Cdc13-Stn1-Ten1 complex|CTC1-OBFC1-TEN1 complex http://purl.obolibrary.org/obo/GO_1990879 UBERON:0009032 biolink:AnatomicalEntity right pulmonary vein Vein that drains right lung and returns blood to the heart. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009032 UBERON:0009035 biolink:AnatomicalEntity renal straight tubule Any region of a nephron tubule that is straight. Examples: distal convoluted tubule, proximal convoluted tuble. go-plus.json straight tubule|kidney straight tubule http://purl.obolibrary.org/obo/UBERON_0009035 GO:1990875 biolink:CellularComponent nucleoplasmic side of nuclear pore The side of the nuclear pore complex (NPC) that faces the nucleoplasm. go-plus.json nucleoplasmic side of nucleopore|nucleoplasmic side of NPC|nucleoplasmic side of nuclear pore complex http://purl.obolibrary.org/obo/GO_1990875 GO:1990876 biolink:CellularComponent cytoplasmic side of nuclear pore The side of the nuclear pore complex (NPC) that faces the cytoplasm. go-plus.json cytoplasmic side of NPC|cytoplasmic side of nucleopore|cytoplasmic side of nuclear pore complex http://purl.obolibrary.org/obo/GO_1990876 GO:1990877 biolink:CellularComponent Lst4-Lst7 complex A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains Follicular (FLCN) and either follicular interaction protein 1 (FNIP1) or FNIP2. go-plus.json FNIP-Folliculin RagC/D GAP complex|FLCN-FNIP2 complex|FLCN-FNIP1 complex http://purl.obolibrary.org/obo/GO_1990877 UBERON:0009039 biolink:AnatomicalEntity lymph node germinal center A germinal center that is located in a lymph node go-plus.json germinal center|lymph node nodule|lymph node light zone|lymph node activated zone|lymph node central zone http://purl.obolibrary.org/obo/UBERON_0009039 GO:1990878 biolink:BiologicalProcess cellular response to gastrin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990878 GO:1990882 biolink:BiologicalProcess rRNA acetylation The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_1990882 CHEBI:27647 biolink:ChemicalSubstance prostaglandin G2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27647 GO:1990883 biolink:MolecularActivity rRNA cytidine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990883 CHEBI:27648 biolink:ChemicalSubstance 3-oxohexanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27648 GO:1990884 biolink:BiologicalProcess RNA acetylation The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990884 GO:1990885 biolink:MolecularActivity obsolete protein serine/threonine kinase binding OBSOLETE. Binding to a protein serine/threonine kinase. go-plus.json http://purl.obolibrary.org/obo/GO_1990885 CHEBI:27644 biolink:ChemicalSubstance chlortetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_27644 CHEBI:27645 biolink:ChemicalSubstance dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27645 GO:1990880 biolink:BiologicalProcess cellular detoxification of copper ion Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration. go-plus.json http://purl.obolibrary.org/obo/GO_1990880 GO:1990881 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to DNA damage OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage. go-plus.json down-regulation of transcription from RNA polymerase II promoter in response to DNA damage|inhibition of transcription from RNA polymerase II promoter in response to DNA damage|down regulation of transcription from RNA polymerase II promoter in response to DNA damage|downregulation of transcription from RNA polymerase II promoter in response to DNA damage http://purl.obolibrary.org/obo/GO_1990881 UBERON:0010011 biolink:AnatomicalEntity collection of basal ganglia Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum. go-plus.json set of basal ganglia|cerebral nuclei|subcortical nuclei|set of basal nuclei|basal nuclei (basal ganglia)|basal ganglia set|basal nuclei|basal ganglia http://purl.obolibrary.org/obo/UBERON_0010011 CHEBI:27641 biolink:ChemicalSubstance cycloheximide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27641 chebi_ph7_3 CHEBI:27642 biolink:ChemicalSubstance methyl tert-butyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_27642 chebi_ph7_3 UBERON:0010009 biolink:AnatomicalEntity aggregate regional part of brain A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]. go-plus.json set of nuclei of neuraxis http://purl.obolibrary.org/obo/UBERON_0010009 GO:1990886 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990886 GO:1990887 biolink:MolecularActivity 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+. go-plus.json http://purl.obolibrary.org/obo/GO_1990887 GO:1990888 biolink:MolecularActivity 2-polyprenyl-6-hydroxyphenol O-methyltransferase activity Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+. go-plus.json http://purl.obolibrary.org/obo/GO_1990888 UBERON:0009027 biolink:AnatomicalEntity vesical artery An artery that supplies blood to the urinary bladder. go-plus.json vesical arteries|arteria vesicali http://purl.obolibrary.org/obo/UBERON_0009027 GO:1990889 biolink:MolecularActivity H4K20me3 modified histone binding Binding to a histone H4 in which the lysine residue at position 20 has been modified by trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_1990889 GO:1990893 biolink:BiologicalProcess mitotic chromosome centromere condensation The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis. go-plus.json mitotic chromosome condensation at kinetochore http://purl.obolibrary.org/obo/GO_1990893 GO:1990894 biolink:BiologicalProcess obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_1990894 GO:1990895 biolink:BiologicalProcess regulation of protein localization to cell cortex of cell tip Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip. go-plus.json http://purl.obolibrary.org/obo/GO_1990895 CHEBI:27616 biolink:ChemicalSubstance psoralen go-plus.json http://purl.obolibrary.org/obo/CHEBI_27616 chebi_ph7_3 GO:1990896 biolink:BiologicalProcess protein localization to cell cortex of cell tip A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip. go-plus.json http://purl.obolibrary.org/obo/GO_1990896 CHEBI:27617 biolink:ChemicalSubstance monensin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_27617 GO:1990890 biolink:MolecularActivity netrin receptor binding Binding to a netrin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_1990890 GO:1990891 biolink:BiologicalProcess mitotic sister chromatid arm separation The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_1990891 CHEBI:27612 biolink:ChemicalSubstance hydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27612 chebi_ph7_3 GO:1990892 biolink:BiologicalProcess mitotic chromosome arm condensation The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990892 CHEBI:27613 biolink:ChemicalSubstance amygdalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27613 chebi_ph7_3 UBERON:0010000 biolink:AnatomicalEntity multicellular anatomical structure An anatomical structure that has more than one cell as a part. go-plus.json multicellular structure http://purl.obolibrary.org/obo/UBERON_0010000 UBERON:0010001 biolink:AnatomicalEntity cell cluster organ A small cluster of cells of various types which form a discrete structure, largely delimited by a morphological boundary and whose components work together to make the whole structure capable of a specific function. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010001 UBERON:0009010 biolink:AnatomicalEntity periurethral tissue Any portion of tissue that surrounds a urethra. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009010 GO:1990897 biolink:CellularComponent obsolete CTDK-1 complex OBSOLETE. A protein complex that phosphorylates serine 2 residues in the CTD domain of productively elongating large subunits of DNA-directed RNA polymerase II, holoenzyme. In S. cerevisiae this complex consists of CTK1/CTK2/CTK3, in S. pombe Lsk1/Lsc1/Lsg1. Human CTK1 homologs include CDK12/13. go-plus.json http://purl.obolibrary.org/obo/GO_1990897 CHEBI:27618 biolink:ChemicalSubstance chalcone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27618 chebi_ph7_3 GO:1990898 biolink:BiologicalProcess meiotic DNA double-strand break clipping The process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. Proteins involved in this process include the MRX/MRN complex and Sae2/Ctp1/RBBP8(CtIP). go-plus.json http://purl.obolibrary.org/obo/GO_1990898 UBERON:0009015 biolink:AnatomicalEntity upper back skin A zone of skin that is part of a dorsal thoracic segment of trunk. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009015 GO:1990899 biolink:BiologicalProcess meiotic DNA double-strand break resectioning The process following clipping in double-strand break processing of SPO11 induced breaks, where long-tract single-stranded 3'-end DNA is generated from naked (SPO11 has been removed) 5' ends. go-plus.json http://purl.obolibrary.org/obo/GO_1990899 CHEBI:27625 biolink:ChemicalSubstance alpha-D-glucosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27625 CHEBI:27626 biolink:ChemicalSubstance 3,4-dehydrothiomorpholine-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27626 CHEBI:27628 biolink:ChemicalSubstance 4-isopropylbenzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27628 chebi_ph7_3 CHEBI:27624 biolink:ChemicalSubstance prostaglandin B1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27624 NCBITaxon:1106 biolink:OrganismalEntity Chloroflexaceae go-plus.json photosynthetic flexibacteria|filamentous anoxygenic phototrophic bacteria http://purl.obolibrary.org/obo/NCBITaxon_1106 GO:1990830 biolink:BiologicalProcess cellular response to leukemia inhibitory factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus. go-plus.json cellular response to CDF|cellular response to cholinergic differentiation factor http://purl.obolibrary.org/obo/GO_1990830 CHEBI:76608 biolink:ChemicalSubstance 2-iminopropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76608 UBERON:0010065 biolink:AnatomicalEntity auditory meatus epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0010065 UBERON:0010063 biolink:AnatomicalEntity tympanic cavity epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0010063 UBERON:0010064 biolink:AnatomicalEntity open anatomical space An anatomical space with at least one opening to another space or the exterior. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010064 NCBITaxon:1107 biolink:OrganismalEntity Chloroflexus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1107 UBERON:0010069 biolink:AnatomicalEntity outer epithelial layer of tympanic membrane A portion of the external acoustic meatus epithelium which makes up the outer (cuticular) layer of the tympanic membrane go-plus.json outer layer of tympanic membrane|outer cuticular layer of tympanic membrane|tympanic membrane external acoustic meatus epithelial component|cuticular layer of tympanic membrane|cuticular stratum of tympanic membrane http://purl.obolibrary.org/obo/UBERON_0010069 NCBITaxon:1108 biolink:OrganismalEntity Chloroflexus aurantiacus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1108 GO:1990839 biolink:BiologicalProcess response to endothelin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3). go-plus.json http://purl.obolibrary.org/obo/GO_1990839 GO:1990835 biolink:BiologicalProcess obsolete insulin-like growth factor production OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IGF production http://purl.obolibrary.org/obo/GO_1990835 GO:1990836 biolink:CellularComponent lysosomal matrix A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_1990836 GO:1990837 biolink:MolecularActivity sequence-specific double-stranded DNA binding Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. go-plus.json sequence-specific dsDNA binding http://purl.obolibrary.org/obo/GO_1990837 GO:1990838 biolink:MolecularActivity poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P). go-plus.json http://purl.obolibrary.org/obo/GO_1990838 GO:1990831 biolink:BiologicalProcess cellular response to carcinoembryonic antigen Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins. go-plus.json cellular response to pregnancy specific glycoprotein http://purl.obolibrary.org/obo/GO_1990831 GO:1990832 biolink:BiologicalProcess slow axonal transport The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition. go-plus.json http://purl.obolibrary.org/obo/GO_1990832 GO:1990833 biolink:MolecularActivity clathrin-uncoating ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_1990833 GO:1990834 biolink:BiologicalProcess response to odorant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell. go-plus.json http://purl.obolibrary.org/obo/GO_1990834 CHEBI:27603 biolink:ChemicalSubstance 1(F)-alpha-D-galactosylraffinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27603 chebi_ph7_3 CHEBI:76614 biolink:ChemicalSubstance 3-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76614 chebi_ph7_3 CHEBI:76615 biolink:ChemicalSubstance 3,18-dihydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76615 chebi_ph7_3 CHEBI:27605 biolink:ChemicalSubstance D-psicose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27605 chebi_ph7_3 GO:1990840 biolink:BiologicalProcess response to lectin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties. go-plus.json http://purl.obolibrary.org/obo/GO_1990840 GO:1990841 biolink:MolecularActivity promoter-specific chromatin binding Binding to a section of chromatin that is associated with gene promoter sequences of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990841 NCBITaxon:1117 biolink:OrganismalEntity Cyanobacteria go-plus.json blue-green bacteria|Cyanophyta|cyanobacteria|Oxygenic photosynthetic bacteria|Cyanophyceae|Oxyphotobacteria|blue-green algae|cyanophytes|Cyanophycota http://purl.obolibrary.org/obo/NCBITaxon_1117 CHEBI:76613 biolink:ChemicalSubstance 3-hydroxypalmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76613 chebi_ph7_3 CHEBI:76618 biolink:ChemicalSubstance 3,12-dihydroxylaurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76618 chebi_ph7_3 CHEBI:76619 biolink:ChemicalSubstance omega-methyl fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76619 chebi_ph7_3 CHEBI:27601 biolink:ChemicalSubstance pteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27601 chebi_ph7_3 CHEBI:76616 biolink:ChemicalSubstance 3-hydroxylaurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76616 chebi_ph7_3 CHEBI:76617 biolink:ChemicalSubstance EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76617 UBERON:0010052 biolink:AnatomicalEntity mucosa of dorsum of tongue A mucosa that is part of a dorsum of tongue. go-plus.json mucosa of dorsal surface of tongue http://purl.obolibrary.org/obo/UBERON_0010052 UBERON:0010053 biolink:AnatomicalEntity echolocation organ Any organ that plays a role in the process of echolocation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010053 UBERON:0010059 biolink:AnatomicalEntity hypoglossal cord go-plus.json http://purl.obolibrary.org/obo/UBERON_0010059 UBERON:0010056 biolink:AnatomicalEntity future tongue A compound organ that has the potential to develop into a tongue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010056 GO:1990846 biolink:MolecularActivity ribonucleoside-diphosphate reductase inhibitor activity Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase. go-plus.json http://purl.obolibrary.org/obo/GO_1990846 GO:1990847 biolink:BiologicalProcess obsolete peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion OBSOLETE. The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types. go-plus.json http://purl.obolibrary.org/obo/GO_1990847 GO:1990848 biolink:BiologicalProcess obsolete Positive regulation of removal of reactive oxygen species OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell. go-plus.json http://purl.obolibrary.org/obo/GO_1990848 GO:1990849 biolink:BiologicalProcess maintenance of vacuolar location Any process in which the vacuole is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of vacuolar localization|maintenance of vacuole localization|maintenance of vacuole location http://purl.obolibrary.org/obo/GO_1990849 GO:1990842 biolink:BiologicalProcess obsolete response to prenatal stress OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy. go-plus.json response to PNS http://purl.obolibrary.org/obo/GO_1990842 CHEBI:76610 biolink:ChemicalSubstance omega-hydroxytetracosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76610 chebi_ph7_3 GO:1990843 biolink:CellularComponent obsolete subsarcolemmal mitochondrion OBSOLETE. A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers. go-plus.json SS mitochondrion|SSM http://purl.obolibrary.org/obo/GO_1990843 GO:1990844 biolink:CellularComponent obsolete interfibrillar mitochondrion OBSOLETE. A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers. go-plus.json IMF mitochondrion|intermyofibrillar mitochondrion|IFM http://purl.obolibrary.org/obo/GO_1990844 CHEBI:27609 biolink:ChemicalSubstance coproporphyrin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_27609 GO:1990845 biolink:BiologicalProcess adaptive thermogenesis The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. go-plus.json http://purl.obolibrary.org/obo/GO_1990845 CHEBI:76625 biolink:ChemicalSubstance 11,12-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76625 chebi_ph7_3 GO:1990850 biolink:CellularComponent H-gal-GP complex A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus. go-plus.json galactose-containing glycoprotein complex|Haemonchus galactose-containing glycoprotein complex http://purl.obolibrary.org/obo/GO_1990850 CHEBI:76626 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76626 GO:1990851 biolink:CellularComponent Wnt-Frizzled-LRP5/6 complex A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6. go-plus.json Frizzled-LRP5/6 complex|Wnt-induced Frizzled-LRP5/6 complex|WNT-FZD-LRP6 complex|WNT-FZD-LRP5 complex|Fz/Wnt/LRP6 complex|Wnt.Fz.LRP ternary complex|Wnt receptor complex|Wnt-FZD-LRP5/6 trimeric complex http://purl.obolibrary.org/obo/GO_1990851 CHEBI:76623 biolink:ChemicalSubstance (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76623 GO:1990852 biolink:BiologicalProcess protein transport along microtubule to spindle pole body The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990852 CHEBI:76624 biolink:ChemicalSubstance 20-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76624 chebi_ph7_3 UBERON:0009050 biolink:AnatomicalEntity nucleus of solitary tract A neural nucleus that is part of the solitary tract nuclear complex. The solitary tract and nucleus are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves. [WP,unvetted]. go-plus.json solitary nucleus|solitary tract nucleus|nucleus of the tractus solitarius|nuclei tractus solitarii|nucleus tractus solitarii|nucleus tractus solitarii medullae oblongatae|nucleus tracti solitarii|nucleus of the solitary tract|nucleus of tractus solitarius|nucleus solitarius|solitary nucleus|solitary nuclear complex http://purl.obolibrary.org/obo/UBERON_0009050 CHEBI:76629 biolink:ChemicalSubstance 2-lysophosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76629 CHEBI:76627 biolink:ChemicalSubstance 19-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76627 chebi_ph7_3 CHEBI:76628 biolink:ChemicalSubstance 11-hydroxylaurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76628 chebi_ph7_3 UBERON:0010042 biolink:AnatomicalEntity 1st arch mesenchyme Mesenchyme that is part of a pharyngeal arch 1. go-plus.json mesenchyme of 1st arch http://purl.obolibrary.org/obo/UBERON_0010042 UBERON:0010047 biolink:AnatomicalEntity oral gland Gland of the epithelium lining the oral cavity. The most common are the salivary glands. go-plus.json oral cavity gland|buccal gland|mouth gland|oral region gland|gland of oral region|gland of oral opening http://purl.obolibrary.org/obo/UBERON_0010047 CHEBI:144097 biolink:ChemicalSubstance EC 1.4.3.2 (L-amino-acid oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_144097 UBERON:0010045 biolink:AnatomicalEntity 1st arch maxillary mesenchyme Mesenchyme that is part of a 1st arch maxillary component. go-plus.json mesenchyme of maxillary component|maxillary component mesenchyme|maxillary mesenchyme http://purl.obolibrary.org/obo/UBERON_0010045 UBERON:0010046 biolink:AnatomicalEntity entire pharyngeal arch associated mesenchyme The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. go-plus.json entire branchial arch associated mesenchyme|pharyngeal arch associated mesenchyme|associated mesenchyme of pharyngeal region http://purl.obolibrary.org/obo/UBERON_0010046 CHEBI:144099 biolink:ChemicalSubstance EC 2.6.1.2 (alanine transaminase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_144099 UBERON:0010039 biolink:AnatomicalEntity food storage organ An organ of the digestive tract that is capable of retaining and storing food go-plus.json http://purl.obolibrary.org/obo/UBERON_0010039 GO:1990857 biolink:CellularComponent obsolete APC-Fzr1/Mfr1 complex OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family. go-plus.json http://purl.obolibrary.org/obo/GO_1990857 GO:1990858 biolink:BiologicalProcess cellular response to lectin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties. go-plus.json http://purl.obolibrary.org/obo/GO_1990858 GO:1990859 biolink:BiologicalProcess cellular response to endothelin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3). go-plus.json http://purl.obolibrary.org/obo/GO_1990859 GO:1990853 biolink:BiologicalProcess histone H2A SQE motif phosphorylation The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_1990853 CHEBI:76621 biolink:ChemicalSubstance (3R,23Z,26Z,29Z,32Z)-3-hydroxyoctatriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76621 GO:1990854 biolink:BiologicalProcess vacuole-ER tethering The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles. go-plus.json vacuole-endoplasmic reticulum tethering|vacuole-endoplasmic reticulum attachment|vacuole-ER attachment http://purl.obolibrary.org/obo/GO_1990854 GO:1990855 biolink:BiologicalProcess obsolete myo-inositol import across plasma membrane OBSOLETE. The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell across the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990855 GO:1990856 biolink:MolecularActivity methionyl-initiator methionine tRNA binding Binding to methionine-initator methionine tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990856 GO:1990860 biolink:CellularComponent Pho85-Pho80 CDK-cyclin complex A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin. go-plus.json http://purl.obolibrary.org/obo/GO_1990860 CHEBI:76636 biolink:ChemicalSubstance 19-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76636 chebi_ph7_3 CHEBI:76637 biolink:ChemicalSubstance (3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76637 GO:1990861 biolink:CellularComponent Ubp3-Bre5 deubiquitination complex A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p. go-plus.json Ubp3-Bre5 ubiquitin protease complex http://purl.obolibrary.org/obo/GO_1990861 GO:1990862 biolink:CellularComponent nuclear membrane complex Bqt3-Bqt4 A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4. go-plus.json http://purl.obolibrary.org/obo/GO_1990862 CHEBI:76634 biolink:ChemicalSubstance 17(R),18(S)-EETeTr(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76634 chebi_ph7_3 GO:1990863 biolink:BiologicalProcess acinar cell proliferation The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus). go-plus.json acinic cell proliferation|acinous cell proliferation http://purl.obolibrary.org/obo/GO_1990863 CHEBI:76635 biolink:ChemicalSubstance 17(S),18(R)-EETeTr(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76635 chebi_ph7_3 CHEBI:76638 biolink:ChemicalSubstance (2E,11Z,14Z,17Z)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76638 UBERON:0009042 biolink:AnatomicalEntity prostatic venous plexus The prostatic veins form a well-marked prostatic plexus which lies partly in the fascial sheath of the prostate and partly between the sheath and the prostatic capsule. It communicates with the pudendal and vesical plexuses. go-plus.json plexus venosus prostaticus|pudendal venous plexus http://purl.obolibrary.org/obo/UBERON_0009042 CHEBI:76639 biolink:ChemicalSubstance 20-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76639 chebi_ph7_3 UBERON:0010032 biolink:AnatomicalEntity anterior part of tongue The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch. go-plus.json anterior 2/3 of the tongue|pars anterior dorsi linguae|apex linguae|front of the tongue|anterior two thirds of the tongue|oral part of the tongue|apex of the tongue|anterior 2/3 of tongue|buccal part of the tongue http://purl.obolibrary.org/obo/UBERON_0010032 UBERON:0010031 biolink:AnatomicalEntity 6th arch mesenchyme Mesenchyme that is part of a pharyngeal arch 6. go-plus.json pharyngeal arch 6 mesenchyme|6th pharyngeal arch mesenchyme|6th branchial arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0010031 UBERON:0010027 biolink:AnatomicalEntity dorsal part of pharyngeal pouch 4 go-plus.json dorsal branchial pouch 4 endoderm|dorsal pharyngeal pouch 4 endoderm|dorsal 4th branchial pouch|dorsal pharyngeal pouch 4 http://purl.obolibrary.org/obo/UBERON_0010027 UBERON:0010028 biolink:AnatomicalEntity ventral part of pharyngeal pouch 4 go-plus.json ventral 4th branchial pouch|ventral pharyngeal pouch 4 endoderm|ventral pharyngeal pouch 4|ventral branchial pouch 4 endoderm http://purl.obolibrary.org/obo/UBERON_0010028 GO:1990868 biolink:BiologicalProcess response to chemokine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990868 GO:1990869 biolink:BiologicalProcess cellular response to chemokine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990869 GO:1990864 biolink:BiologicalProcess response to growth hormone-releasing hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins. go-plus.json response to sermorelin|response to GHRF|response to GRF|response to somatorelin|response to somatocrinin|response to growth hormone-releasing factor|response to somatoliberin http://purl.obolibrary.org/obo/GO_1990864 GO:1990865 biolink:BiologicalProcess obsolete response to intermittent hypoxia OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an episodic stimulus indicating lowered oxygen tension. go-plus.json http://purl.obolibrary.org/obo/GO_1990865 CHEBI:76633 biolink:ChemicalSubstance 17,18-EETeTr(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76633 chebi_ph7_3 GO:1990866 biolink:BiologicalProcess obsolete response to sustained hypoxia OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sustained stimulus indicating lowered oxygen tension. go-plus.json http://purl.obolibrary.org/obo/GO_1990866 GO:1990867 biolink:BiologicalProcess response to gastrin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990867 CHEBI:76631 biolink:ChemicalSubstance 1-lysophosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76631 GO:0001532 biolink:MolecularActivity interleukin-21 receptor activity Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-21 receptor activity|IL-21R http://purl.obolibrary.org/obo/GO_0001532 NCBITaxon:1148 biolink:OrganismalEntity Synechocystis sp. PCC 6803 go-plus.json Synechocystis sp. (strain PCC 6803)|Aphanocapsa sp. (strain N-1)|Synechocystis sp. (PCC 6803)|Synechocystis sp. (ATCC 27184)|Synechocystis sp. ATCC 27184|Aphanocapsa sp. N-1 http://purl.obolibrary.org/obo/NCBITaxon_1148 GO:0001533 biolink:CellularComponent cornified envelope A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes). go-plus.json http://purl.obolibrary.org/obo/GO_0001533 GO:0001534 biolink:CellularComponent radial spoke Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules. Wikipedia:Radial_spoke go-plus.json http://purl.obolibrary.org/obo/GO_0001534 goslim_pir GO:0001535 biolink:CellularComponent radial spoke head Protein complex forming part of eukaryotic flagellar apparatus. go-plus.json radial spokehead http://purl.obolibrary.org/obo/GO_0001535 GO:0001530 biolink:MolecularActivity lipopolysaccharide binding Binding to a lipopolysaccharide. go-plus.json LPS binding|endotoxin binding http://purl.obolibrary.org/obo/GO_0001530 CHEBI:52678 biolink:ChemicalSubstance 3-methoxyphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52678 chebi_ph7_3 GO:0001531 biolink:MolecularActivity interleukin-21 receptor binding Binding to an interleukin-21 receptor. go-plus.json interleukin-21 receptor ligand|IL-21 http://purl.obolibrary.org/obo/GO_0001531 CHEBI:52679 biolink:ChemicalSubstance 5-alkylresorcinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52679 chebi_ph7_3 GO:1902258 biolink:BiologicalProcess positive regulation of apoptotic process involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. go-plus.json up-regulation of apoptosis involved in outflow tract morphogenesis|up-regulation of apoptotic process involved in outflow tract morphogenesis|upregulation of apoptosis involved in outflow tract morphogenesis|upregulation of apoptotic process involved in outflow tract morphogenesis|up regulation of apoptosis involved in outflow tract morphogenesis|positive regulation of apoptosis involved in outflow tract morphogenesis|up regulation of apoptotic process involved in outflow tract morphogenesis|activation of apoptosis involved in outflow tract morphogenesis|activation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902258 GO:1902259 biolink:BiologicalProcess regulation of delayed rectifier potassium channel activity Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902259 GO:1902256 biolink:BiologicalProcess regulation of apoptotic process involved in outflow tract morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. go-plus.json regulation of apoptosis involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902256 GO:1902257 biolink:BiologicalProcess negative regulation of apoptotic process involved in outflow tract morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. go-plus.json down-regulation of apoptotic process involved in outflow tract morphogenesis|inhibition of apoptosis involved in outflow tract morphogenesis|inhibition of apoptotic process involved in outflow tract morphogenesis|down regulation of apoptosis involved in outflow tract morphogenesis|downregulation of apoptosis involved in outflow tract morphogenesis|down regulation of apoptotic process involved in outflow tract morphogenesis|downregulation of apoptotic process involved in outflow tract morphogenesis|down-regulation of apoptosis involved in outflow tract morphogenesis|negative regulation of apoptosis involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902257 GO:1902254 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. go-plus.json inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway by p53 class mediator|downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway by p53 class mediator|negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator http://purl.obolibrary.org/obo/GO_1902254 GO:1902255 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. go-plus.json upregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|upregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|up-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|positive regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway by p53 class mediator|up-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|activation of intrinsic apoptotic signaling pathway by p53 class mediator http://purl.obolibrary.org/obo/GO_1902255 GO:1902263 biolink:BiologicalProcess apoptotic process involved in embryonic digit morphogenesis Any apoptotic process that is involved in embryonic digit morphogenesis. go-plus.json apoptotic program involved in embryonic digit morphogenesis|programmed cell death by apoptosis involved in embryonic digit morphogenesis|apoptosis involved in embryonic digit morphogenesis|signaling (initiator) caspase activity involved in embryonic digit morphogenesis|type I programmed cell death involved in embryonic digit morphogenesis|apoptotic cell death involved in embryonic digit morphogenesis|apoptotic programmed cell death involved in embryonic digit morphogenesis http://purl.obolibrary.org/obo/GO_1902263 CHEBI:37039 biolink:ChemicalSubstance pyrimidine ribonucleoside 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37039 GO:1902264 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902264 GO:1902261 biolink:BiologicalProcess positive regulation of delayed rectifier potassium channel activity Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity. go-plus.json upregulation of delayed rectifier potassium channel activity|up-regulation of delayed rectifier potassium channel activity|activation of delayed rectifier potassium channel activity|up regulation of delayed rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_1902261 CHEBI:37037 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37037 GO:1902262 biolink:BiologicalProcess apoptotic process involved in blood vessel morphogenesis Any apoptotic process that is involved in blood vessel morphogenesis. go-plus.json apoptosis involved in patterning of blood vessels|type I programmed cell death involved in patterning of blood vessels|signaling (initiator) caspase activity involved in patterning of blood vessels|apoptotic cell death involved in patterning of blood vessels|apoptotic programmed cell death involved in patterning of blood vessels|apoptotic program involved in patterning of blood vessels|programmed cell death by apoptosis involved in patterning of blood vessels http://purl.obolibrary.org/obo/GO_1902262 CHEBI:37038 biolink:ChemicalSubstance purine ribonucleoside 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37038 GO:1902260 biolink:BiologicalProcess negative regulation of delayed rectifier potassium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity. go-plus.json down regulation of delayed rectifier potassium channel activity|inhibition of delayed rectifier potassium channel activity|down-regulation of delayed rectifier potassium channel activity|downregulation of delayed rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_1902260 CHEBI:37030 biolink:ChemicalSubstance 3-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37030 chebi_ph7_3 GO:0001536 biolink:CellularComponent radial spoke stalk Globular portion of the radial spoke that projects towards the central pair of microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0001536 CHEBI:37035 biolink:ChemicalSubstance 3-hydroxyhexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37035 GO:0001537 biolink:MolecularActivity N-acetylgalactosamine 4-O-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate. Reactome:R-HSA-3636919|Reactome:R-HSA-6786034|Reactome:R-HSA-2022063 go-plus.json N-acetylgalactosamine 4-O-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0001537 CHEBI:37036 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37036 GO:0001538 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001538 GO:0001539 biolink:BiologicalProcess cilium or flagellum-dependent cell motility Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. go-plus.json ciliary/flagellar motility|ciliary or bacterial-type flagellar motility http://purl.obolibrary.org/obo/GO_0001539 gocheck_do_not_manually_annotate CHEBI:37034 biolink:ChemicalSubstance O-acetyl-D-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37034 GO:0001543 biolink:BiologicalProcess ovarian follicle rupture Disruption of theca cell layer releasing follicular fluid and/or the oocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0001543 CHEBI:52669 biolink:ChemicalSubstance 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52669 GO:0001544 biolink:BiologicalProcess initiation of primordial ovarian follicle growth Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle). go-plus.json http://purl.obolibrary.org/obo/GO_0001544 GO:0001545 biolink:BiologicalProcess primary ovarian follicle growth Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle). go-plus.json http://purl.obolibrary.org/obo/GO_0001545 GO:0001546 biolink:BiologicalProcess preantral ovarian follicle growth Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation. go-plus.json http://purl.obolibrary.org/obo/GO_0001546 GO:0001540 biolink:MolecularActivity amyloid-beta binding Binding to an amyloid-beta peptide/protein. go-plus.json beta-amyloid binding http://purl.obolibrary.org/obo/GO_0001540 goslim_chembl CHEBI:37050 biolink:ChemicalSubstance 3-hydroxybutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_37050 GO:0001541 biolink:BiologicalProcess ovarian follicle development The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. go-plus.json follicular phase http://purl.obolibrary.org/obo/GO_0001541 GO:0001542 biolink:BiologicalProcess ovulation from ovarian follicle The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0001542 CHEBI:52668 biolink:ChemicalSubstance 1,4-dihydroxy-2-naphthoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52668 GO:1902269 biolink:BiologicalProcess positive regulation of polyamine transmembrane transport Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport. go-plus.json up regulation of polyamine transmembrane transport|activation of polyamine transmembrane transport|up-regulation of polyamine transmembrane transport|upregulation of polyamine transmembrane transport http://purl.obolibrary.org/obo/GO_1902269 GO:1902267 biolink:BiologicalProcess regulation of polyamine transmembrane transport Any process that modulates the frequency, rate or extent of polyamine transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1902267 GO:1902268 biolink:BiologicalProcess negative regulation of polyamine transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport. go-plus.json down-regulation of polyamine transmembrane transport|inhibition of polyamine transmembrane transport|down regulation of polyamine transmembrane transport|downregulation of polyamine transmembrane transport http://purl.obolibrary.org/obo/GO_1902268 GO:1902265 biolink:BiologicalProcess abscisic acid homeostasis Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell. go-plus.json 2-cis-abscisate homeostasis|ABA homeostasis http://purl.obolibrary.org/obo/GO_1902265 GO:1902266 biolink:BiologicalProcess cellular abscisic acid homeostasis Any biological process involved in the maintenance of an internal steady state of abscisic acid at the level of the cell. go-plus.json cellular ABA homeostasis|cellular 2-cis-abscisate homeostasis http://purl.obolibrary.org/obo/GO_1902266 GO:1902274 biolink:BiologicalProcess positive regulation of (R)-carnitine transmembrane transport Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport. go-plus.json up regulation of (R)-carnitine transmembrane transport|activation of (R)-carnitine transmembrane transport|up-regulation of (R)-carnitine transmembrane transport|upregulation of (R)-carnitine transmembrane transport http://purl.obolibrary.org/obo/GO_1902274 GO:1902275 biolink:BiologicalProcess regulation of chromatin organization Any process that modulates the frequency, rate or extent of chromatin organization. go-plus.json regulation of chromatin modification|regulation of establishment or maintenance of chromatin architecture|regulation of chromatin organisation http://purl.obolibrary.org/obo/GO_1902275 GO:1902272 biolink:BiologicalProcess regulation of (R)-carnitine transmembrane transport Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1902272 GO:1902273 biolink:BiologicalProcess negative regulation of (R)-carnitine transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport. go-plus.json down regulation of (R)-carnitine transmembrane transport|downregulation of (R)-carnitine transmembrane transport|down-regulation of (R)-carnitine transmembrane transport|inhibition of (R)-carnitine transmembrane transport http://purl.obolibrary.org/obo/GO_1902273 CHEBI:37049 biolink:ChemicalSubstance (S)-3-hydroxyhexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37049 GO:1902270 biolink:BiologicalProcess (R)-carnitine transmembrane transport The process in which (R)-carnitine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902270 GO:1990806 biolink:BiologicalProcess ligand-gated ion channel signaling pathway A series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription. go-plus.json ligand-gated ion channel signalling pathway http://purl.obolibrary.org/obo/GO_1990806 GO:1990807 biolink:MolecularActivity obsolete protein N-acetyltransferase activity OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990807 GO:1902271 biolink:MolecularActivity D3 vitamins binding Binding to D3 vitamins. go-plus.json http://purl.obolibrary.org/obo/GO_1902271 GO:1990808 biolink:MolecularActivity F-bar domain binding Binding to an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990808 GO:1990809 biolink:BiologicalProcess endoplasmic reticulum tubular network membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990809 GO:1990802 biolink:BiologicalProcess obsolete protein phosphorylation involved in DNA double-strand break processing OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing. go-plus.json protein amino acid phosphorylation involved in DNA double-strand break processing http://purl.obolibrary.org/obo/GO_1990802 CHEBI:37042 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37042 GO:1990803 biolink:BiologicalProcess obsolete protein phosphorylation involved in protein localization to spindle microtubule OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule. go-plus.json protein phosphorylation involved in protein localization in spindle microtubule|protein phosphorylation involved in protein localisation in spindle microtubule|protein amino acid phosphorylation involved in protein localization in spindle microtubule|protein amino acid phosphorylation involved in protein localisation in spindle microtubule|protein phosphorylation involved in protein localisation to spindle microtubule|protein amino acid phosphorylation involved in protein localization to spindle microtubule|protein amino acid phosphorylation involved in protein localisation to spindle microtubule http://purl.obolibrary.org/obo/GO_1990803 CHEBI:37043 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37043 GO:1990804 biolink:BiologicalProcess obsolete protein phosphorylation involved in double-strand break repair via nonhomologous end joining OBSOLETE. Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining. go-plus.json protein amino acid phosphorylation involved in double-strand break repair via nonhomologous end joining|protein amino acid phosphorylation involved in NHEJ|protein phosphorylation involved in NHEJ http://purl.obolibrary.org/obo/GO_1990804 CHEBI:37040 biolink:ChemicalSubstance C-nucleoside phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37040 GO:1990805 biolink:CellularComponent central cylinder A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_1990805 CHEBI:37041 biolink:ChemicalSubstance N-methyl-2-oxoglutaramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37041 GO:0001547 biolink:BiologicalProcess antral ovarian follicle growth Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0001547 CHEBI:37046 biolink:ChemicalSubstance p-menth-8-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_37046 chebi_ph7_3 GO:0001548 biolink:BiologicalProcess follicular fluid formation in ovarian follicle antrum The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis. go-plus.json ovarian follicle antrum/follicular fluid formation|ovarian follicle antrum/follicular fluid biosynthesis http://purl.obolibrary.org/obo/GO_0001548 CHEBI:37047 biolink:ChemicalSubstance (+)-cis-isopulegone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37047 chebi_ph7_3 GO:0001549 biolink:BiologicalProcess cumulus cell differentiation The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell. go-plus.json ovarian cumulus cell differentiation http://purl.obolibrary.org/obo/GO_0001549 GO:1990800 biolink:CellularComponent obsolete meiotic APC-fizzy-related complex OBSOLETE. An anaphase promoting complex bound to a fizzy-related family APC activator that regulates meiotic exit by activating the APC/C to target meiotic cyclins for destruction during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_1990800 CHEBI:37044 biolink:ChemicalSubstance pyrimidine ribonucleoside 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37044 GO:1990801 biolink:BiologicalProcess obsolete protein phosphorylation involved in mitotic spindle assembly OBSOLETE. Any protein phosphorylation that is involved in mitotic spindle assembly. go-plus.json protein phosphorylation involved in spindle assembly involved in mitosis|protein amino acid phosphorylation involved in mitotic spindle assembly|protein amino acid phosphorylation involved in spindle assembly involved in mitosis http://purl.obolibrary.org/obo/GO_1990801 CHEBI:37045 biolink:ChemicalSubstance purine ribonucleoside 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37045 GO:0001510 biolink:BiologicalProcess RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor. go-plus.json http://purl.obolibrary.org/obo/GO_0001510 GO:0001511 biolink:MolecularActivity obsolete fibrillin OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome. go-plus.json fibrillin http://purl.obolibrary.org/obo/GO_0001511 GO:0001512 biolink:MolecularActivity dihydronicotinamide riboside quinone reductase activity Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone. EC:1.10.5.1|Reactome:R-HSA-8936519|MetaCyc:1.10.99.2-RXN|RHEA:12364 go-plus.json N-ribosyldihydronicotinamide dehydrogenase (quinone) activity|ribosyldihydronicotinamide dehydrogenase (quinone) activity|NQO2|quinone reductase 2 activity|QR2 activity|NQO(2) activity|NRH:quinone oxidoreductase 2 activity http://purl.obolibrary.org/obo/GO_0001512 GO:0001513 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001513 CHEBI:27698 biolink:ChemicalSubstance vanadium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27698 chebi_ph7_3 CHEBI:52656 biolink:ChemicalSubstance O-acyltropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52656 chebi_ph7_3 CHEBI:52657 biolink:ChemicalSubstance O-acylpseudotropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52657 chebi_ph7_3 CHEBI:27696 biolink:ChemicalSubstance prostaglandin D1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27696 GO:1902278 biolink:BiologicalProcess positive regulation of pancreatic amylase secretion Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion. go-plus.json upregulation of pancreatic amylase secretion|up-regulation of pancreatic amylase secretion|activation of pancreatic amylase secretion|up regulation of pancreatic amylase secretion http://purl.obolibrary.org/obo/GO_1902278 GO:1902279 biolink:BiologicalProcess positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion. go-plus.json upregulation of pancreatic amylase secretion by cholecystokinin signaling pathway|CCK-mediated pancreatic amylase secretion|CCK-induced amylase release in pancreatic cell|up regulation of pancreatic amylase secretion by cholecystokinin signaling pathway|activation of pancreatic amylase secretion by cholecystokinin signaling pathway|cholecystokinin-mediated pancreatic amylase secretion|CCK-stimulated pancreatic amylase release|up-regulation of pancreatic amylase secretion by cholecystokinin signaling pathway http://purl.obolibrary.org/obo/GO_1902279 CHEBI:27691 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_27691 GO:1902276 biolink:BiologicalProcess regulation of pancreatic amylase secretion Any process that modulates the frequency, rate or extent of pancreatic amylase secretion. go-plus.json http://purl.obolibrary.org/obo/GO_1902276 CHEBI:27692 biolink:ChemicalSubstance lipid II go-plus.json http://purl.obolibrary.org/obo/CHEBI_27692 GO:1902277 biolink:BiologicalProcess negative regulation of pancreatic amylase secretion Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion. go-plus.json inhibition of pancreatic amylase secretion|down-regulation of pancreatic amylase secretion|downregulation of pancreatic amylase secretion|down regulation of pancreatic amylase secretion http://purl.obolibrary.org/obo/GO_1902277 CHEBI:27693 biolink:ChemicalSubstance sitosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27693 chebi_ph7_3 GO:1902285 biolink:BiologicalProcess semaphorin-plexin signaling pathway involved in neuron projection guidance Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance. go-plus.json semaphorin-plexin signaling pathway involved in neuron protrusion guidance|semaphorin-plexin signalling pathway involved in neurite guidance|semaphorin-plexin signaling pathway involved in neuronal cell projection guidance|semaphorin-plexin signalling pathway involved in neuron process guidance|semaphorin-plexin signalling pathway involved in neuron protrusion guidance|semaphorin-plexin signaling pathway involved in neurite guidance|semaphorin-plexin signalling pathway involved in neuronal cell projection guidance|semaphorin-plexin signaling pathway involved in neuron process guidance|semaphorin-plexin signalling pathway involved in neuron projection guidance http://purl.obolibrary.org/obo/GO_1902285 GO:1902286 biolink:BiologicalProcess semaphorin-plexin signaling pathway involved in dendrite guidance Any semaphorin-plexin signaling pathway that is involved in dendrite guidance. go-plus.json semaphorin-plexin signalling pathway involved in dendritic guidance|semaphorin-plexin signalling pathway involved in dendrite guidance|semaphorin-plexin signaling pathway involved in dendritic guidance http://purl.obolibrary.org/obo/GO_1902286 CHEBI:37018 biolink:ChemicalSubstance pyrimidine ribonucleoside 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37018 GO:1902283 biolink:BiologicalProcess negative regulation of primary amine oxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity. go-plus.json downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of amine oxidase (copper-containing) activity|down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity|down-regulation of primary amine oxidase activity|down-regulation of amine oxidase (copper-containing) activity|negative regulation of amine oxidase (copper-containing) activity|downregulation of primary amine oxidase activity|down regulation of primary amine oxidase activity|inhibition of primary amine oxidase activity|downregulation of amine oxidase (copper-containing) activity|negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down regulation of amine oxidase (copper-containing) activity http://purl.obolibrary.org/obo/GO_1902283 CHEBI:37015 biolink:ChemicalSubstance ribonucleoside 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37015 GO:1902284 biolink:BiologicalProcess neuron projection extension involved in neuron projection guidance Any neuron projection extension that is involved in neuron projection guidance. go-plus.json neuron projection extension involved in neuron process guidance|neuronal cell projection extension involved in neurite guidance|neurite extension involved in neuron protrusion guidance|neuron protrusion extension involved in neurite guidance|neuron process extension involved in neuron protrusion guidance|neuron process extension involved in neuronal cell projection guidance|neuron projection extension involved in neuronal cell projection guidance|neuronal cell projection extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron process guidance|neuron projection extension involved in neurite guidance|neurite extension involved in neuron process guidance|neurite extension involved in neuron projection guidance|neuronal cell projection extension involved in neuron process guidance|neuron process extension involved in neuron projection guidance|neuron process extension involved in neurite guidance|neuron protrusion extension involved in neuronal cell projection guidance|neurite extension involved in neuronal cell projection guidance|neuronal cell projection extension involved in neuronal cell projection guidance|neuron process extension involved in neuron process guidance|neurite extension involved in neurite guidance|neuronal cell projection extension involved in neuron projection guidance|neuron projection extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron projection guidance http://purl.obolibrary.org/obo/GO_1902284 CHEBI:37016 biolink:ChemicalSubstance 2'-deoxyribonucleoside 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37016 GO:1902281 biolink:BiologicalProcess negative regulation of RNA helicase activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity. go-plus.json negative regulation of ATP-dependent RNA helicase activity|down regulation of ATP-dependent RNA helicase activity|downregulation of ATP-dependent RNA helicase activity|down-regulation of ATP-dependent RNA helicase activity|inhibition of ATP-dependent RNA helicase activity http://purl.obolibrary.org/obo/GO_1902281 GO:1990817 biolink:MolecularActivity RNA adenylyltransferase activity Catalysis of the template-independent extension of the 3'- end of an RNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA, or oligo(A) bearing a 3'-OH terminal group. go-plus.json http://purl.obolibrary.org/obo/GO_1990817 GO:1902282 biolink:MolecularActivity voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1902282 GO:1990818 biolink:BiologicalProcess L-arginine transmembrane export from vacuole The directed movement of L-arginine out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990818 GO:1990819 biolink:CellularComponent actin fusion focus A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location. go-plus.json http://purl.obolibrary.org/obo/GO_1990819 GO:1902280 biolink:BiologicalProcess regulation of RNA helicase activity Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity. go-plus.json regulation of ATP-dependent RNA helicase activity http://purl.obolibrary.org/obo/GO_1902280 GO:1990813 biolink:BiologicalProcess meiotic centromeric cohesion protection The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions. go-plus.json protection of centromeric cohesion during meiotic anaphase I http://purl.obolibrary.org/obo/GO_1990813 GO:0001518 biolink:CellularComponent voltage-gated sodium channel complex A sodium channel in a cell membrane whose opening is governed by the membrane potential. NIF_Subcellular:sao785001660 go-plus.json voltage-sensitive sodium channel complex|voltage-dependent sodium channel complex|voltage gated sodium channel complex http://purl.obolibrary.org/obo/GO_0001518 CHEBI:13086 biolink:ChemicalSubstance L-aspartate 4-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_13086 GO:1990814 biolink:MolecularActivity DNA/DNA annealing activity An activity that faciliates the formation of a complementary double-stranded DNA molecule. go-plus.json DNA reannealing activity http://purl.obolibrary.org/obo/GO_1990814 CHEBI:52651 biolink:ChemicalSubstance leptomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52651 GO:0001519 biolink:BiologicalProcess peptide amidation The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions. go-plus.json http://purl.obolibrary.org/obo/GO_0001519 CHEBI:37010 biolink:ChemicalSubstance ribonucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37010 GO:1990815 biolink:BiologicalProcess obsolete regulation of protein localization to cell division site after cytokinesis OBSOLETE. Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in cell separation after cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_1990815 GO:1990816 biolink:CellularComponent vacuole-mitochondrion membrane contact site A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles. go-plus.json vacuole and mitochondria patch|vCLAMP http://purl.obolibrary.org/obo/GO_1990816 GO:0001514 biolink:BiologicalProcess selenocysteine incorporation The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine. RESID:AA0022 go-plus.json http://purl.obolibrary.org/obo/GO_0001514 CHEBI:37013 biolink:ChemicalSubstance ribonucleoside 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37013 CHEBI:37014 biolink:ChemicalSubstance 2'-deoxyribonucleoside 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37014 GO:1990810 biolink:BiologicalProcess microtubule anchoring at mitotic spindle pole body Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end. go-plus.json http://purl.obolibrary.org/obo/GO_1990810 GO:0001515 biolink:MolecularActivity opioid peptide activity Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect. go-plus.json http://purl.obolibrary.org/obo/GO_0001515 goslim_chembl GO:1990811 biolink:CellularComponent MWP complex A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin. go-plus.json Msd1-Wdr8-Pkl1 complex http://purl.obolibrary.org/obo/GO_1990811 CHEBI:37011 biolink:ChemicalSubstance 4-oxoproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_37011 GO:0001516 biolink:BiologicalProcess prostaglandin biosynthetic process The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring. go-plus.json prostaglandin anabolism|prostaglandin synthesis|prostaglandin formation|prostaglandin biosynthesis http://purl.obolibrary.org/obo/GO_0001516 GO:0001517 biolink:MolecularActivity N-acetylglucosamine 6-O-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate. Reactome:R-HSA-6786012|Reactome:R-HSA-2046222|Reactome:R-HSA-3656269 go-plus.json N-acetylglucosamine 6-O-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0001517 goslim_chembl GO:1990812 biolink:CellularComponent growth cone filopodium A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone. go-plus.json http://purl.obolibrary.org/obo/GO_1990812 CHEBI:37012 biolink:ChemicalSubstance L-3-oxoalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37012 GO:0001521 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001521 GO:0001522 biolink:BiologicalProcess pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs. Wikipedia:Pseudouridylation|Wikipedia:Pseudouridine go-plus.json pseudouridylation http://purl.obolibrary.org/obo/GO_0001522 CHEBI:52648 biolink:ChemicalSubstance N(beta)-acyl-L-2,3-diaminopropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52648 GO:0001523 biolink:BiologicalProcess retinoid metabolic process The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. go-plus.json retinoid metabolism http://purl.obolibrary.org/obo/GO_0001523 CHEBI:52649 biolink:ChemicalSubstance 1-O-oleoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52649 GO:0001524 biolink:MolecularActivity obsolete globin OBSOLETE. The colorless and basic protein moiety of hemoglobin and myoglobins. go-plus.json globin http://purl.obolibrary.org/obo/GO_0001524 GO:0001520 biolink:CellularComponent outer dense fiber A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins. go-plus.json outer dense fibre http://purl.obolibrary.org/obo/GO_0001520 CHEBI:52646 biolink:ChemicalSubstance leptomycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_52646 GO:1902289 biolink:BiologicalProcess negative regulation of defense response to oomycetes Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes. go-plus.json down-regulation of defense response to oomycetes|inhibition of defense response to oomycetes|down regulation of defense response to oomycetes|downregulation of defense response to oomycetes http://purl.obolibrary.org/obo/GO_1902289 GO:1902287 biolink:BiologicalProcess semaphorin-plexin signaling pathway involved in axon guidance Any semaphorin-plexin signaling pathway that is involved in axon guidance. go-plus.json semaphorin-plexin signalling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon guidance|semaphorin-plexin signaling pathway involved in axon growth cone guidance|semaphorin-plexin signalling pathway involved in axon chemotaxis|semaphorin-plexin signaling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon growth cone guidance|semaphorin-plexin signaling pathway involved in axon chemotaxis http://purl.obolibrary.org/obo/GO_1902287 GO:1902288 biolink:BiologicalProcess regulation of defense response to oomycetes Any process that modulates the frequency, rate or extent of defense response to oomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_1902288 GO:1902296 biolink:BiologicalProcess DNA strand elongation involved in cell cycle DNA replication Any DNA strand elongation that is involved in cell cycle DNA replication. go-plus.json DNA replication elongation involved in cell cycle DNA replication|DNA strand elongation during DNA replication involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902296 GO:1902297 biolink:BiologicalProcess cell cycle DNA replication DNA unwinding Any DNA unwinding that is involved in cell cycle DNA replication. go-plus.json DNA unwinding during replication involved in cell cycle DNA replication|DNA unwinding factor involved in cell cycle DNA replication|DNA unwinding involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902297 GO:1902294 biolink:BiologicalProcess cell cycle DNA replication termination Any DNA replication termination that is involved in cell cycle DNA replication. go-plus.json DNA replication termination involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902294 GO:1902295 biolink:BiologicalProcess synthesis of RNA primer involved in cell cycle DNA replication Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication. go-plus.json DNA replication, synthesis of RNA primer involved in cell cycle DNA replication|replication priming involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902295 GO:1902292 biolink:BiologicalProcess cell cycle DNA replication initiation Any DNA replication initiation that is involved in cell cycle DNA replication. go-plus.json DNA endoreduplication initiation involved in cell cycle DNA replication|DNA re-replication initiation involved in cell cycle DNA replication|DNA replication initiation involved in cell cycle DNA replication|DNA-dependent DNA replication initiation involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902292 GO:1990828 biolink:BiologicalProcess hepatocyte dedifferentiation The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. go-plus.json http://purl.obolibrary.org/obo/GO_1990828 GO:1902293 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902293 GO:1990829 biolink:MolecularActivity C-rich single-stranded DNA binding Binding to C-rich, single-stranded DNA. go-plus.json C-rich ssDNA binding http://purl.obolibrary.org/obo/GO_1990829 GO:1902290 biolink:BiologicalProcess positive regulation of defense response to oomycetes Any process that activates or increases the frequency, rate or extent of defense response to oomycetes. go-plus.json up regulation of defense response to oomycetes|activation of defense response to oomycetes|up-regulation of defense response to oomycetes|upregulation of defense response to oomycetes http://purl.obolibrary.org/obo/GO_1902290 GO:1902291 biolink:BiologicalProcess cell cycle DNA replication DNA ligation Any DNA ligation that is involved in cell cycle DNA replication. go-plus.json DNA ligation involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902291 GO:1990824 biolink:CellularComponent obsolete magnesium-dependent protein complex OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex. go-plus.json http://purl.obolibrary.org/obo/GO_1990824 CHEBI:37020 biolink:ChemicalSubstance purine ribonucleoside 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37020 GO:0001529 biolink:CellularComponent obsolete elastin OBSOLETE. (Was not defined before being made obsolete). go-plus.json elastin http://purl.obolibrary.org/obo/GO_0001529 GO:1990825 biolink:MolecularActivity sequence-specific mRNA binding Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif. go-plus.json http://purl.obolibrary.org/obo/GO_1990825 CHEBI:37021 biolink:ChemicalSubstance purine ribonucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37021 CHEBI:52640 biolink:ChemicalSubstance N-acylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52640 chebi_ph7_3 GO:1990826 biolink:CellularComponent nucleoplasmic periphery of the nuclear pore complex Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex. go-plus.json associated with the nuclear pore http://purl.obolibrary.org/obo/GO_1990826 CHEBI:52641 biolink:ChemicalSubstance polyphosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52641 GO:1990827 biolink:MolecularActivity deaminase binding Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3). go-plus.json http://purl.obolibrary.org/obo/GO_1990827 NCBITaxon:1142 biolink:OrganismalEntity Synechocystis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1142 GO:1990820 biolink:BiologicalProcess response to mitotic DNA integrity checkpoint signaling A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling. go-plus.json response to signal involved in mitotic DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_1990820 GO:0001525 biolink:BiologicalProcess angiogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. Wikipedia:Angiogenesis go-plus.json blood vessel formation from pre-existing blood vessels http://purl.obolibrary.org/obo/GO_0001525 CHEBI:37024 biolink:ChemicalSubstance 2-aminoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37024 GO:1990821 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990821 GO:0001526 biolink:BiologicalProcess obsolete proteoglycan sulfate transfer OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate. go-plus.json proteoglycan sulphate transfer|proteoglycan sulfate transfer http://purl.obolibrary.org/obo/GO_0001526 CHEBI:37025 biolink:ChemicalSubstance D-2-aminoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37025 CHEBI:37022 biolink:ChemicalSubstance amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_37022 GO:1990822 biolink:BiologicalProcess basic amino acid transmembrane transport The directed movement of basic amino acids from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1990822 GO:0001527 biolink:CellularComponent microfibril Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins. go-plus.json fibrillin|extended fibrils http://purl.obolibrary.org/obo/GO_0001527 GO:1990823 biolink:BiologicalProcess response to leukemia inhibitory factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus. go-plus.json response to LIF|response to cholinergic differentiation factor|response to CDF http://purl.obolibrary.org/obo/GO_1990823 GO:0001528 biolink:MolecularActivity obsolete elastin OBSOLETE. A major structural protein of mammalian connective tissues; composed of one third glycine, and also rich in proline, alanine, and valine. Chains are cross-linked together via lysine residues. go-plus.json elastin http://purl.obolibrary.org/obo/GO_0001528 CHEBI:37023 biolink:ChemicalSubstance L-2-aminoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37023 CHEBI:52639 biolink:ChemicalSubstance N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52639 chebi_ph7_3 CHEBI:27676 biolink:ChemicalSubstance L-histidinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_27676 CHEBI:27678 biolink:ChemicalSubstance dTDP-3-dehydro-6-deoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27678 CHEBI:27675 biolink:ChemicalSubstance chlorohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27675 chebi_ph7_3 GO:1902298 biolink:BiologicalProcess cell cycle DNA replication maintenance of fidelity Any maintenance of fidelity that is involved in cell cycle DNA replication. go-plus.json maintenance of fidelity during DNA-dependent DNA replication involved in cell cycle DNA replication|maintenance of fidelity involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902298 CHEBI:27670 biolink:ChemicalSubstance 1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27670 chebi_ph7_3 GO:1902299 biolink:BiologicalProcess pre-replicative complex assembly involved in cell cycle DNA replication Any pre-replicative complex assembly that is involved in cell cycle DNA replication. go-plus.json pre-replication complex assembly involved in cell cycle DNA replication|pre-RC assembly involved in cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902299 CHEBI:13022 biolink:ChemicalSubstance keto-D-sorbose go-plus.json http://purl.obolibrary.org/obo/CHEBI_13022 chebi_ph7_3 CHEBI:52625 biolink:ChemicalSubstance inorganic hydroxy compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_52625 GO:0001501 biolink:BiologicalProcess skeletal system development The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). go-plus.json skeletal development http://purl.obolibrary.org/obo/GO_0001501 GO:0001502 biolink:BiologicalProcess cartilage condensation The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0001502 CHEBI:27689 biolink:ChemicalSubstance decanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27689 chebi_ph7_3 CHEBI:27684 biolink:ChemicalSubstance phenylmercury acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27684 CHEBI:52629 biolink:ChemicalSubstance EC 3.1.26.13 (retroviral ribonuclease H) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_52629 CHEBI:27680 biolink:ChemicalSubstance galactomannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27680 CHEBI:27681 biolink:ChemicalSubstance (S)-2-acetyl-2-hydroxybutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27681 CHEBI:37007 biolink:ChemicalSubstance nicotinamide dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37007 CHEBI:37005 biolink:ChemicalSubstance (3S,5R)-1-pyrroline-3-hydroxy-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37005 CHEBI:37008 biolink:ChemicalSubstance nicotinic acid mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37008 CHEBI:37009 biolink:ChemicalSubstance ribonucleoside 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37009 GO:0001507 biolink:BiologicalProcess acetylcholine catabolic process in synaptic cleft The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission. go-plus.json acetylcholine breakdown in synaptic cleft|acetylcholine degradation in synaptic cleft http://purl.obolibrary.org/obo/GO_0001507 GO:0001508 biolink:BiologicalProcess action potential A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. go-plus.json http://purl.obolibrary.org/obo/GO_0001508 GO:0001509 biolink:MolecularActivity obsolete legumain activity OBSOLETE. Catalysis of the hydrolysis of proteins and small-molecule substrates at Asn-Xaa bonds. go-plus.json legumain activity|hemoglobinase activity|asparaginyl endopeptidase activity|bean endopeptidase activity|proteinase B|phaseolin activity|PRSC1 gene product (Homo sapiens)|vicilin peptidohydrolase activity|citvac http://purl.obolibrary.org/obo/GO_0001509 GO:0001503 biolink:BiologicalProcess ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. Wikipedia:Ossification go-plus.json bone formation|osteogenesis|bone biosynthesis http://purl.obolibrary.org/obo/GO_0001503 GO:0001504 biolink:BiologicalProcess neurotransmitter uptake The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. go-plus.json neurotransmitter import into neuron|neurotransmitter import into glial cell|neurotransmitter recycling|neurotransmitter import http://purl.obolibrary.org/obo/GO_0001504 goslim_synapse GO:0001505 biolink:BiologicalProcess regulation of neurotransmitter levels Any process that modulates levels of neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0001505 GO:0001506 biolink:BiologicalProcess obsolete neurotransmitter biosynthetic process and storage OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules. go-plus.json neurotransmitter biosynthetic process and storage|neurotransmitter anabolism and storage|neurotransmitter synthesis and storage|neurotransmitter formation and storage http://purl.obolibrary.org/obo/GO_0001506 CHEBI:52615 biolink:ChemicalSubstance 4-formylzymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52615 chebi_ph7_3 CHEBI:27659 biolink:ChemicalSubstance 2-oxo aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27659 chebi_ph7_3 CHEBI:52617 biolink:ChemicalSubstance 7,8-dihydro-8-oxoguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52617 chebi_ph7_3 CHEBI:27656 biolink:ChemicalSubstance camptothecin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27656 chebi_ph7_3 CHEBI:27657 biolink:ChemicalSubstance N-succinyl-L-glutamic 5-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27657 CHEBI:27652 biolink:ChemicalSubstance 2',3'-cyclic CMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_27652 CHEBI:52618 biolink:ChemicalSubstance 2-hydroxy carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52618 CHEBI:13043 biolink:ChemicalSubstance 3-amino-L-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13043 CHEBI:52603 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52603 CHEBI:27666 biolink:ChemicalSubstance actinomycin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_27666 chebi_ph7_3 CHEBI:27667 biolink:ChemicalSubstance beta-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27667 chebi_ph7_3 CHEBI:52602 biolink:ChemicalSubstance ganglioside GP1c go-plus.json http://purl.obolibrary.org/obo/CHEBI_52602 CHEBI:27668 biolink:ChemicalSubstance (S)-3-hydroxylauroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27668 CHEBI:27660 biolink:ChemicalSubstance pyrrole-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27660 chebi_ph7_3 GO:0050422 biolink:MolecularActivity strictosidine beta-glucosidase activity Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone. RHEA:12917|KEGG_REACTION:R03820|MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN|EC:3.2.1.105 go-plus.json strictosidine b-glucosidase activity|strictosidine beta-D-glucohydrolase activity http://purl.obolibrary.org/obo/GO_0050422 GO:0050423 biolink:MolecularActivity thiamine oxidase activity Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2. EC:1.1.3.23|MetaCyc:THIAMIN-OXIDASE-RXN|RHEA:21280 go-plus.json thiamine:oxygen 5-oxidoreductase activity|thiamin oxidase activity|thiamine dehydrogenase activity|thiamin:oxygen 5-oxidoreductase activity|thiamin dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050423 GO:0050420 biolink:MolecularActivity maltose synthase activity Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate. MetaCyc:MALTOSE-SYNTHASE-RXN|RHEA:22320|EC:2.4.1.139 go-plus.json alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating) http://purl.obolibrary.org/obo/GO_0050420 GO:0050421 biolink:MolecularActivity nitrite reductase (NO-forming) activity Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+. MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN|RHEA:15233|EC:1.7.2.1 go-plus.json nitric-oxide:ferricytochrome-c oxidoreductase activity|nitrite reductase (cytochrome; NO-forming) activity|[nitrite reductase (cytochrome)]|cd-cytochrome nitrite reductase activity|cytochrome cd activity|NO-forming nitrite reductase (cytochrome) activity|Pseudomonas cytochrome oxidase activity|cytochrome cd1 activity|cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity|NO-forming nitrite reductase activity|methyl viologen-nitrite reductase activity|cytochrome c-551:O2, NO2+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050421 GO:0050426 biolink:MolecularActivity obsolete peptidyl-glycinamidase activity OBSOLETE. Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide. go-plus.json peptidyl-glycinamidase activity|peptidyl carboxyamidase activity|peptidyl carboxy-amidase activity|carboxyamidase activity|peptidyl amino acid amide hydrolase activity|carboxamidopeptidase activity http://purl.obolibrary.org/obo/GO_0050426 GO:0050427 biolink:BiologicalProcess 3'-phosphoadenosine 5'-phosphosulfate metabolic process The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. MetaCyc:PWY-5340 go-plus.json adenosine 3'-phosphate 5'-phosphosulfate metabolism|PAPS metabolic process|PAPS metabolism|adenosine 3'-phosphate 5'-phosphosulfate metabolic process|3'-phosphoadenylyl-sulfate metabolism|phosphoadenosine phosphosulfate metabolic process|3'-phosphoadenosine 5'-phosphosulphate metabolism|3'-phosphoadenosine 5'-phosphosulfate metabolism|3'-phosphoadenosine 5'-phosphosulphate metabolic process|phosphoadenosine phosphosulfate metabolism|3'-phosphoadenylyl-sulfate metabolic process http://purl.obolibrary.org/obo/GO_0050427 GO:0050424 biolink:MolecularActivity obsolete alanine carboxypeptidase activity OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups. go-plus.json alanine carboxypeptidase activity|N-benzoyl-L-alanine-amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050424 GO:0050425 biolink:MolecularActivity obsolete carboxypeptidase B activity OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid. go-plus.json carboxypeptidase B activity|tissue carboxypeptidase B|pancreatic carboxypeptidase B|protaminase activity|peptidyl-L-lysine [L-arginine]hydrolase activity http://purl.obolibrary.org/obo/GO_0050425 GO:0050428 biolink:BiologicalProcess 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. go-plus.json 3'-phosphoadenosine 5'-phosphosulfate anabolism|3'-phosphoadenosine 5'-phosphosulfate synthesis|PAPS biosynthesis|PAPS biosynthetic process|3'-phosphoadenosine 5'-phosphosulfate formation|3'-phosphoadenylyl-sulfate biosynthetic process|3'-phosphoadenylyl-sulfate biosynthesis|3'-phosphoadenosine 5'-phosphosulphate biosynthesis|3'-phosphoadenosine 5'-phosphosulphate biosynthetic process|3'-phosphoadenosine 5'-phosphosulfate biosynthesis|phosphoadenosine phosphosulfate biosynthesis|phosphoadenosine phosphosulfate biosynthetic process|adenosine 3'-phosphate 5'-phosphosulfate biosynthetic process|adenosine 3'-phosphate 5'-phosphosulfate biosynthesis http://purl.obolibrary.org/obo/GO_0050428 GO:0050429 biolink:MolecularActivity calcium-dependent phospholipase C activity Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+. go-plus.json http://purl.obolibrary.org/obo/GO_0050429 CL:0000362 biolink:Cell epidermal cell An epithelial cell of the integument (the outer layer of an organism). go-plus.json cell of epidermis|epithelial cell of skin http://purl.obolibrary.org/obo/CL_0000362 CL:0000365 biolink:Cell animal zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. go-plus.json zygote http://purl.obolibrary.org/obo/CL_0000365 GO:0050433 biolink:BiologicalProcess regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. go-plus.json http://purl.obolibrary.org/obo/GO_0050433 GO:0050434 biolink:BiologicalProcess positive regulation of viral transcription Any process that activates or increases the frequency, rate or extent of viral transcription. go-plus.json up regulation of viral transcription|activation of viral transcription|stimulation of viral transcription|up-regulation of viral transcription|upregulation of viral transcription http://purl.obolibrary.org/obo/GO_0050434 GO:0050431 biolink:MolecularActivity transforming growth factor beta binding Binding to TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. go-plus.json TGFbeta binding|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type I receptor|TGF-beta binding http://purl.obolibrary.org/obo/GO_0050431 GO:0050432 biolink:BiologicalProcess catecholamine secretion The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_0050432 GO:0050437 biolink:MolecularActivity (-)-endo-fenchol synthase activity Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate. MetaCyc:4.2.3.10-RXN|RHEA:20565|KEGG_REACTION:R02004|EC:4.2.3.10 go-plus.json (-)-endo-fenchol cyclase activity|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]|geranyl pyrophosphate:(-)-endo-fenchol cyclase activity http://purl.obolibrary.org/obo/GO_0050437 GO:0050438 biolink:MolecularActivity 2-ethylmalate synthase activity Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+). EC:2.3.3.6|MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN|RHEA:23040|KEGG_REACTION:R00998 go-plus.json propylmalate synthase activity|(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity|propylmalic synthase activity|acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|2-ethylmalate-3-hydroxybutanedioate synthase activity http://purl.obolibrary.org/obo/GO_0050438 GO:0050435 biolink:BiologicalProcess amyloid-beta metabolic process The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP). go-plus.json beta-amyloid metabolism|amyloid-beta metabolism|beta-amyloid metabolic process http://purl.obolibrary.org/obo/GO_0050435 GO:0050436 biolink:MolecularActivity microfibril binding Binding to a microfibril, any small fibril occurring in biological material. go-plus.json http://purl.obolibrary.org/obo/GO_0050436 GO:0050439 biolink:MolecularActivity 2-hydroxy-3-oxoadipate synthase activity Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2). KEGG_REACTION:R00474|RHEA:14341|EC:2.2.1.5|MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN go-plus.json oxoglutarate:glyoxylate carboligase activity|2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity|2-hydroxy-3-oxoadipate synthetase activity|2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)|alpha-ketoglutaric-glyoxylic carboligase activity|oxoglutarate: glyoxylate carboligase activity http://purl.obolibrary.org/obo/GO_0050439 CL:0000373 biolink:Cell histoblast go-plus.json http://purl.obolibrary.org/obo/CL_0000373 GO:0050430 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050430 GO:0050444 biolink:MolecularActivity obsolete aquacobalamin reductase (NADPH) activity OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+. RHEA:20752|MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN|EC:1.16.1.5 go-plus.json cob(II)alamin:NADP+ oxidoreductase activity|NADPH-linked aquacobalamin reductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity|NADPH:aquacob(III)alamin oxidoreductase activity|NADPH2:aquacob(III)alamin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050444 GO:0050445 biolink:MolecularActivity asparagusate reductase activity Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH. EC:1.8.1.11|KEGG_REACTION:R03761|RHEA:14881|MetaCyc:ASPARAGUSATE-REDUCTASE-NADH-RXN go-plus.json asparagusate reductase (NADH2)|asparagusic dehydrogenase activity|3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity|asparagusate reductase (NADH) activity|NADH:asparagusate oxidoreductase activity|asparagusate dehydrogenase activity|NADH2:asparagusate oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050445 GO:0050442 biolink:MolecularActivity 3-propylmalate synthase activity Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+). EC:2.3.3.12|RHEA:14457|MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN|KEGG_REACTION:R03040 go-plus.json 3-(n-propyl)-malate synthase activity|3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity|N-propylmalate synthase activity|pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)|beta-n-propylmalate synthase activity http://purl.obolibrary.org/obo/GO_0050442 GO:0050443 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050443 GO:0050448 biolink:MolecularActivity beta-cyclopiazonate dehydrogenase activity Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2). EC:1.21.99.1|RHEA:14525|KEGG_REACTION:R04080|MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN go-plus.json beta-cyclopiazonic oxidocyclase activity|beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)|beta-cyclopiazonate oxidocyclase activity|beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)|b-cyclopiazonate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050448 GO:0050449 biolink:MolecularActivity casbene synthase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate. RHEA:14901|EC:4.2.3.8|KEGG_REACTION:R02064|MetaCyc:CASBENE-SYNTHASE-RXN go-plus.json casbene synthetase activity|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing) http://purl.obolibrary.org/obo/GO_0050449 GO:0050446 biolink:MolecularActivity azobenzene reductase activity Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+. MetaCyc:AZOBENZENE-REDUCTASE-RXN|EC:1.7.1.6|RHEA:16269|UM-BBD_reactionID:r0808 go-plus.json NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity|azo reductase activity|NC-reductase activity|azo-dye reductase activity|New coccine (NC)-reductase activity|nicotinamide adenine dinucleotide (phosphate) azoreductase activity|dibromopropylaminophenylazobenzoic azoreductase activity|new coccine (NC)-reductase|orange I azoreductase activity|N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity|orange II azoreductase activity|NADPH2-dependent azoreductase activity|azoreductase activity|methyl red azoreductase activity|NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity|NADPH:4-(dimethylamino)azobenzene oxidoreductase activity|dimethylaminobenzene reductase activity|NADPH-dependent azoreductase activity|p-dimethylaminoazobenzene azoreductase activity|N,N-dimethyl-4-phenylazoaniline azoreductase activity|p-aminoazobenzene reductase activity http://purl.obolibrary.org/obo/GO_0050446 GO:0050447 biolink:MolecularActivity zeatin 9-aminocarboxyethyltransferase activity Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+). EC:2.5.1.50|KEGG_REACTION:R03133|RHEA:17333|MetaCyc:BETA-9-CYTOKININ-ALANINE-SYNTHASE-RXN go-plus.json O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity|beta-(9-cytokinin)-alanine synthase activity|lupinic acid synthase activity|lupinate synthetase activity|3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity|O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)|lupinic acid synthetase activity|beta-(9-cytokinin)alanine synthase activity|O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity http://purl.obolibrary.org/obo/GO_0050447 CL:0000349 biolink:Cell extraembryonic cell go-plus.json http://purl.obolibrary.org/obo/CL_0000349 CL:0000341 biolink:Cell pigment cell (sensu Nematoda and Protostomia) go-plus.json http://purl.obolibrary.org/obo/CL_0000341 GO:0050440 biolink:MolecularActivity 2-methylcitrate synthase activity Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+). KEGG_REACTION:R00931|EC:2.3.3.5|RHEA:23780|MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN go-plus.json propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)|methylcitrate synthase activity|2-methylcitrate oxaloacetate-lyase activity|methylcitrate synthetase activity|MCS activity http://purl.obolibrary.org/obo/GO_0050440 GO:0050441 biolink:MolecularActivity 3-ethylmalate synthase activity Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+). RHEA:10500|EC:2.3.3.7|MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN|KEGG_REACTION:R01180 go-plus.json 2-ethyl-3-hydroxybutanedioate synthase activity|3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity|butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming) http://purl.obolibrary.org/obo/GO_0050441 GO:0050455 biolink:MolecularActivity columbamine oxidase activity Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O. EC:1.21.3.2|MetaCyc:COLUMBAMINE-OXIDASE-RXN|RHEA:23564|KEGG_REACTION:R00044 go-plus.json berberine synthase activity|columbamine:oxygen oxidoreductase (cyclizing) http://purl.obolibrary.org/obo/GO_0050455 GO:0050456 biolink:MolecularActivity cystine reductase activity Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH. MetaCyc:CYSTINE-REDUCTASE-NADH-RXN|RHEA:20597|KEGG_REACTION:R00892|EC:1.8.1.6 go-plus.json NADH:L-cystine oxidoreductase activity|NADH-dependent cystine reductase activity|cystine reductase (NADH2)|L-cysteine:NAD+ oxidoreductase|cystine reductase (NADH) activity|NADH2:L-cystine oxidoreductase http://purl.obolibrary.org/obo/GO_0050456 GO:0050453 biolink:MolecularActivity cob(II)alamin reductase activity Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH. RHEA:17481|Reactome:R-HSA-3149560|MetaCyc:COBIIALAMIN-REDUCTASE-RXN|KEGG_REACTION:R00099|EC:1.16.1.4 go-plus.json vitamin B12 reduction|vitamin B12 reductase activity|vitamin B12r reductase activity|B(12r) reductase activity|NADH2:cob(II)alamin oxidoreductase activity|NADH:cob(II)alamin oxidoreductase activity|vitamin B(12r) reductase activity|cob(I)alamin:NAD+ oxidoreductase activity|B12r reductase activity http://purl.obolibrary.org/obo/GO_0050453 GO:0050454 biolink:MolecularActivity coenzyme F420 hydrogenase activity Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420. MetaCyc:COENZYME-F420-HYDROGENASE-RXN|EC:1.12.98.1|KEGG_REACTION:R03025|RHEA:23760 go-plus.json 8-hydroxy-5-deazaflavin-reducing hydrogenase activity|coenzyme F420-dependent hydrogenase activity|hydrogen:coenzyme F420 oxidoreductase activity|F420-reducing hydrogenase activity http://purl.obolibrary.org/obo/GO_0050454 GO:1902209 biolink:BiologicalProcess negative regulation of bacterial-type flagellum assembly Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly. go-plus.json inhibition of bacterial-type flagellum assembly|down-regulation of bacterial flagellum assembly|negative regulation of bacterial flagellum assembly|down regulation of bacterial-type flagellum assembly|downregulation of bacterial flagellum assembly|downregulation of bacterial-type flagellum assembly|down regulation of bacterial flagellum assembly|inhibition of bacterial flagellum assembly|down-regulation of bacterial-type flagellum assembly http://purl.obolibrary.org/obo/GO_1902209 GO:0050459 biolink:MolecularActivity ethanolamine-phosphate phospho-lyase activity Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate. EC:4.2.3.2|MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN|KEGG_REACTION:R00748|Reactome:R-HSA-5696415|RHEA:17889 go-plus.json O-phosphorylethanol-amine phospho-lyase activity|ethanolamine-phosphate phospho-lyase (deaminating)|amino alcohol O-phosphate phospholyase activity|ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)|O-phosphoethanolamine-phospholyase activity http://purl.obolibrary.org/obo/GO_0050459 GO:1902207 biolink:BiologicalProcess positive regulation of interleukin-2-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway. go-plus.json up regulation of IL-2-mediated signaling pathway|activation of IL-2-mediated signaling pathway|positive regulation of IL-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signalling pathway|upregulation of interleukin-2-mediated signaling pathway|up-regulation of IL-2-mediated signaling pathway|upregulation of interleukin-2-mediated signalling pathway|activation of interleukin-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signaling pathway|upregulation of IL-2-mediated signaling pathway|up regulation of interleukin-2-mediated signalling pathway|activation of interleukin-2-mediated signalling pathway|positive regulation of interleukin-2-mediated signalling pathway|up regulation of interleukin-2-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902207 GO:0050457 biolink:MolecularActivity decylcitrate synthase activity Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+). EC:2.3.3.2|MetaCyc:DECYLCITRATE-SYNTHASE-RXN|KEGG_REACTION:R03735|RHEA:16605 go-plus.json dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)|(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity|2-decylcitrate synthase activity|(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating) http://purl.obolibrary.org/obo/GO_0050457 GO:1902208 biolink:BiologicalProcess regulation of bacterial-type flagellum assembly Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly. go-plus.json regulation of bacterial flagellum assembly http://purl.obolibrary.org/obo/GO_1902208 GO:0050458 biolink:MolecularActivity decylhomocitrate synthase activity Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+). EC:2.3.3.4|MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN|KEGG_REACTION:R03859|RHEA:10364 go-plus.json 3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)|3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity|dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)|2-decylhomocitrate synthase activity http://purl.obolibrary.org/obo/GO_0050458 GO:1902205 biolink:BiologicalProcess regulation of interleukin-2-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway. go-plus.json regulation of interleukin-2-mediated signalling pathway|regulation of IL-2-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902205 GO:1902206 biolink:BiologicalProcess negative regulation of interleukin-2-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway. go-plus.json down regulation of interleukin-2-mediated signaling pathway|inhibition of interleukin-2-mediated signalling pathway|down-regulation of IL-2-mediated signaling pathway|negative regulation of IL-2-mediated signaling pathway|inhibition of interleukin-2-mediated signaling pathway|inhibition of IL-2-mediated signaling pathway|down regulation of interleukin-2-mediated signalling pathway|downregulation of interleukin-2-mediated signalling pathway|down-regulation of interleukin-2-mediated signaling pathway|down regulation of IL-2-mediated signaling pathway|downregulation of IL-2-mediated signaling pathway|negative regulation of interleukin-2-mediated signalling pathway|down-regulation of interleukin-2-mediated signalling pathway|downregulation of interleukin-2-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902206 CL:0000359 biolink:Cell vascular associated smooth muscle cell A smooth muscle cell assocatiated with the vasculature. go-plus.json vascular smooth muscle cell|VSMC http://purl.obolibrary.org/obo/CL_0000359 GO:1902203 biolink:BiologicalProcess negative regulation of hepatocyte growth factor receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway. go-plus.json downregulation of HGF receptor signalling pathway|inhibition of Met signaling pathway|down-regulation of HGF receptor signaling pathway|negative regulation of HGF receptor signaling pathway|down regulation of hepatocyte growth factor receptor signaling pathway|down-regulation of HGF receptor signalling pathway|negative regulation of HGF receptor signalling pathway|down regulation of Met signaling pathway|downregulation of hepatocyte growth factor receptor signaling pathway|downregulation of Met signaling pathway|downregulation of HGF receptor signaling pathway|down-regulation of hepatocyte growth factor receptor signaling pathway|down regulation of HGF receptor signaling pathway|inhibition of HGF receptor signalling pathway|negative regulation of Met signaling pathway|down-regulation of Met signaling pathway|inhibition of hepatocyte growth factor receptor signaling pathway|inhibition of HGF receptor signaling pathway|down regulation of HGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_1902203 GO:1902204 biolink:BiologicalProcess positive regulation of hepatocyte growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway. go-plus.json up-regulation of HGF receptor signaling pathway|up regulation of HGF receptor signalling pathway|upregulation of hepatocyte growth factor receptor signaling pathway|positive regulation of HGF receptor signalling pathway|activation of HGF receptor signaling pathway|upregulation of Met signaling pathway|activation of HGF receptor signalling pathway|positive regulation of HGF receptor signaling pathway|up regulation of HGF receptor signaling pathway|up regulation of hepatocyte growth factor receptor signaling pathway|up-regulation of HGF receptor signalling pathway|activation of hepatocyte growth factor receptor signaling pathway|up regulation of Met signaling pathway|positive regulation of Met signaling pathway|upregulation of HGF receptor signaling pathway|activation of Met signaling pathway|upregulation of HGF receptor signalling pathway|up-regulation of hepatocyte growth factor receptor signaling pathway|up-regulation of Met signaling pathway http://purl.obolibrary.org/obo/GO_1902204 GO:1902201 biolink:BiologicalProcess negative regulation of bacterial-type flagellum-dependent cell motility Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility. go-plus.json inhibition of flagellin-based flagellar cell motility|negative regulation of bacterial-type flagellar cell motility|down regulation of flagellin-based flagellar cell motility|downregulation of flagellin-based flagellar cell motility|down-regulation of bacterial-type flagellar cell motility|negative regulation of flagellin-based flagellar cell motility|down-regulation of flagellin-based flagellar cell motility|downregulation of bacterial-type flagellar cell motility|down regulation of bacterial-type flagellar cell motility|inhibition of bacterial-type flagellar cell motility http://purl.obolibrary.org/obo/GO_1902201 GO:1902202 biolink:BiologicalProcess regulation of hepatocyte growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway. go-plus.json regulation of Met signaling pathway|regulation of HGF receptor signaling pathway|regulation of HGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_1902202 GO:1902200 biolink:BiologicalProcess 3-methylbut-2-enoyl-CoA(4-) biosynthetic process The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-). go-plus.json 3-methylbut-2-enoyl-CoA(4-) formation|3-methylbut-2-enoyl-CoA(4-) biosynthesis|3-methylbut-2-enoyl-CoA(4-) anabolism|3-methylbut-2-enoyl-CoA(4-) synthesis http://purl.obolibrary.org/obo/GO_1902200 CL:0000350 biolink:Cell amnioserosal cell go-plus.json http://purl.obolibrary.org/obo/CL_0000350 CL:0000351 biolink:Cell trophoblast cell A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface. go-plus.json trophoblastic cell http://purl.obolibrary.org/obo/CL_0000351 CL:0000355 biolink:Cell multi-potent skeletal muscle stem cell A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. go-plus.json http://purl.obolibrary.org/obo/CL_0000355 CL:0000357 biolink:Cell stratified epithelial stem cell go-plus.json http://purl.obolibrary.org/obo/CL_0000357 GO:0050451 biolink:MolecularActivity CoA-disulfide reductase activity Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+. RHEA:14705|MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN|EC:1.8.1.14 go-plus.json CoA-disulfide reductase (NAD(P)H) activity|CoA-disulfide reductase (NADH2)|CoA:NAD+ oxidoreductase activity|coenzyme A disulfide reductase activity|CoA-disulfide reductase (NADH) activity|CoA:NAD(P)+ oxidoreductase activity|CoA-disulfide reductase [NAD(P)H]|CoA-disulphide reductase activity|NADH2:CoA-disulfide oxidoreductase activity|CoADR activity|NADH:CoA-disulfide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050451 GO:0050452 biolink:MolecularActivity CoA-glutathione reductase activity Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+. RHEA:14617|MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN|EC:1.8.1.10 go-plus.json glutathione:NADP+ oxidoreductase (CoA-acylating)|NADPH:CoA-glutathione oxidoreductase activity|NADPH2:CoA-glutathione oxidoreductase activity|coenzyme A disulfide-glutathione reductase activity|NADPH-dependent coenzyme A-SS-glutathione reductase activity|CoA-glutathione reductase (NADPH) activity|coenzyme A glutathione disulfide reductase activity http://purl.obolibrary.org/obo/GO_0050452 GO:0050450 biolink:MolecularActivity citrate (Re)-synthase activity Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group. MetaCyc:CITRATE-RE-SYNTHASE-RXN|EC:2.3.3.3 go-plus.json acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]|(R)-citrate synthase activity|citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]|citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity|Re-citrate-synthase activity http://purl.obolibrary.org/obo/GO_0050450 GO:0050466 biolink:MolecularActivity obsolete oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is not disulfide or oxygen. go-plus.json oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors http://purl.obolibrary.org/obo/GO_0050466 GO:0050467 biolink:MolecularActivity pentalenene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene. KEGG_REACTION:R02305|EC:4.2.3.7|MetaCyc:PENTALENENE-SYNTHASE-RXN|RHEA:18081 go-plus.json pentalenene synthetase activity|2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming) http://purl.obolibrary.org/obo/GO_0050467 GO:0050464 biolink:MolecularActivity nitrate reductase (NADPH) activity Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+. MetaCyc:NITRATE-REDUCTASE-NADPH-RXN|EC:1.7.1.3|RHEA:19061 go-plus.json NADPH:nitrate reductase activity|NADPH:nitrate oxidoreductase activity|nitrate reductase (NADPH2)|assimilatory NADPH-nitrate reductase activity|triphosphopyridine nucleotide-nitrate reductase activity|NADPH-nitrate reductase activity|nitrate reductase (NADPH(2)) activity|assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity|assimilatory nitrate reductase activity|nitrite:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050464 GO:0050465 biolink:MolecularActivity nitroquinoline-N-oxide reductase activity Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+. MetaCyc:1.7.1.9-RXN|EC:1.7.1.9 go-plus.json NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity|4-nitroquinoline 1-oxide reductase activity|NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity|4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity|4NQO reductase activity http://purl.obolibrary.org/obo/GO_0050465 GO:1902218 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway in response to osmotic stress Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. go-plus.json http://purl.obolibrary.org/obo/GO_1902218 GO:0050468 biolink:MolecularActivity reticuline oxidase activity Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+). KEGG_REACTION:R03831|RHEA:19885|EC:1.21.3.3|MetaCyc:RETICULINE-OXIDASE-RXN go-plus.json BBE|(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)|berberine bridge enzyme activity|berberine-bridge-forming enzyme activity|tetrahydroprotoberberine synthase activity http://purl.obolibrary.org/obo/GO_0050468 GO:1902219 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. go-plus.json down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress http://purl.obolibrary.org/obo/GO_1902219 GO:0050469 biolink:MolecularActivity sabinene-hydrate synthase activity Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate. KEGG_REACTION:R02006|EC:4.2.3.11|RHEA:19565|MetaCyc:4.2.3.11-RXN go-plus.json sabinene hydrate cyclase activity|geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming) http://purl.obolibrary.org/obo/GO_0050469 GO:1902216 biolink:BiologicalProcess positive regulation of interleukin-4-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway. go-plus.json activation of interleukin-4-mediated signaling pathway|up regulation of interleukin-4-mediated signalling pathway|positive regulation of interleukin-4-mediated signalling pathway|activation of interleukin-4-mediated signalling pathway|upregulation of IL-4-mediated signaling pathway|up regulation of interleukin-4-mediated signaling pathway|up regulation of IL-4-mediated signaling pathway|up-regulation of interleukin-4-mediated signalling pathway|positive regulation of IL-4-mediated signaling pathway|activation of IL-4-mediated signaling pathway|upregulation of interleukin-4-mediated signaling pathway|upregulation of interleukin-4-mediated signalling pathway|up-regulation of IL-4-mediated signaling pathway|up-regulation of interleukin-4-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902216 CL:0000325 biolink:Cell stuff accumulating cell A cell that is specialised to accumulate a particular substance(s). go-plus.json http://purl.obolibrary.org/obo/CL_0000325 GO:1902217 biolink:BiologicalProcess erythrocyte apoptotic process Any apoptotic process in an erythrocyte. go-plus.json RBC apoptosis|red blood cell apoptotic process|RBC apoptotic process|erythrocyte apoptosis|red blood cell apoptosis http://purl.obolibrary.org/obo/GO_1902217 GO:1902214 biolink:BiologicalProcess regulation of interleukin-4-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway. go-plus.json regulation of IL-4-mediated signaling pathway|regulation of interleukin-4-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1902214 CL:0000327 biolink:Cell extracellular matrix secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000327 GO:1902215 biolink:BiologicalProcess negative regulation of interleukin-4-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway. go-plus.json down-regulation of interleukin-4-mediated signaling pathway|negative regulation of interleukin-4-mediated signalling pathway|down-regulation of interleukin-4-mediated signalling pathway|down regulation of IL-4-mediated signaling pathway|downregulation of IL-4-mediated signaling pathway|inhibition of interleukin-4-mediated signalling pathway|downregulation of interleukin-4-mediated signaling pathway|down regulation of interleukin-4-mediated signaling pathway|inhibition of interleukin-4-mediated signaling pathway|down-regulation of IL-4-mediated signaling pathway|negative regulation of IL-4-mediated signaling pathway|inhibition of IL-4-mediated signaling pathway|down regulation of interleukin-4-mediated signalling pathway|downregulation of interleukin-4-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1902215 CL:0000328 biolink:Cell myelin accumulating cell go-plus.json http://purl.obolibrary.org/obo/CL_0000328 GO:1902212 biolink:BiologicalProcess negative regulation of prolactin signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway. go-plus.json down regulation of prolactin signaling pathway|inhibition of PRL signaling pathway|downregulation of prolactin signaling pathway|negative regulation of prolactin-mediated signaling pathway|down-regulation of prolactin-mediated signaling pathway|down-regulation of prolactin signaling pathway|down regulation of PRL signaling pathway|downregulation of prolactin-mediated signaling pathway|downregulation of PRL signaling pathway|down regulation of prolactin-mediated signaling pathway|inhibition of prolactin-mediated signaling pathway|inhibition of prolactin signaling pathway|down-regulation of PRL signaling pathway|negative regulation of PRL signaling pathway http://purl.obolibrary.org/obo/GO_1902212 CL:0000329 biolink:Cell oxygen accumulating cell go-plus.json http://purl.obolibrary.org/obo/CL_0000329 GO:1902213 biolink:BiologicalProcess positive regulation of prolactin signaling pathway Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway. go-plus.json up-regulation of PRL signaling pathway|up regulation of prolactin signaling pathway|activation of prolactin signaling pathway|positive regulation of prolactin-mediated signaling pathway|up regulation of prolactin-mediated signaling pathway|upregulation of PRL signaling pathway|up-regulation of prolactin signaling pathway|upregulation of prolactin-mediated signaling pathway|up regulation of PRL signaling pathway|activation of PRL signaling pathway|positive regulation of PRL signaling pathway|upregulation of prolactin signaling pathway|up-regulation of prolactin-mediated signaling pathway|activation of prolactin-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902213 GO:1902210 biolink:BiologicalProcess positive regulation of bacterial-type flagellum assembly Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly. go-plus.json up-regulation of bacterial flagellum assembly|activation of bacterial flagellum assembly|up-regulation of bacterial-type flagellum assembly|positive regulation of bacterial flagellum assembly|upregulation of bacterial-type flagellum assembly|up regulation of bacterial flagellum assembly|up regulation of bacterial-type flagellum assembly|upregulation of bacterial flagellum assembly|activation of bacterial-type flagellum assembly http://purl.obolibrary.org/obo/GO_1902210 GO:1902211 biolink:BiologicalProcess regulation of prolactin signaling pathway Any process that modulates the frequency, rate or extent of prolactin signaling pathway. go-plus.json regulation of PRL signaling pathway|regulation of prolactin-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902211 GO:1902220 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. go-plus.json up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|activation of intrinsic apoptotic signaling pathway in response to osmotic stress http://purl.obolibrary.org/obo/GO_1902220 CL:0000322 biolink:Cell pneumocyte An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. go-plus.json pneumonocyte|alveolar epithelial cell http://purl.obolibrary.org/obo/CL_0000322 CHEBI:52595 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52595 chebi_ph7_3 GO:0050462 biolink:MolecularActivity N-acetylneuraminate synthase activity Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate. EC:2.5.1.56|MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN|RHEA:19273 go-plus.json N-acetylneuraminic acid synthase activity|phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity|(NANA)condensing enzyme activity|NeuAc synthase activity http://purl.obolibrary.org/obo/GO_0050462 GO:0050463 biolink:MolecularActivity nitrate reductase [NAD(P)H] activity Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+. EC:1.7.1.2 go-plus.json nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NAD(P)H-nitrate reductase activity|nitrate reductase NAD(P)H activity|nitrite:NAD(P)+ oxidoreductase activity|assimilatory nitrate reductase activity|NAD(P)H bispecific nitrate reductase activity|NAD(P)H2:nitrate oxidoreductase activity|NAD(P)H:nitrate oxidoreductase activity|assimilatory NAD(P)H-nitrate reductase activity|nitrate reductase [NAD(P)H2] http://purl.obolibrary.org/obo/GO_0050463 CHEBI:52592 biolink:ChemicalSubstance N-retinylidene-N-retinylphosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52592 GO:0050460 biolink:MolecularActivity hydroxylamine reductase (NADH) activity Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+. EC:1.7.1.10|RHEA:20581|MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN go-plus.json NADH:hydroxylamine oxidoreductase activity|ammonium:NAD+ oxidoreductase activity|NADH-hydroxylamine reductase activity|hydroxylamine reductase (NADH2)|N-hydroxy amine reductase activity|ammonium dehydrogenase activity|NADH2:hydroxylamine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050460 GO:0050461 biolink:MolecularActivity L-mimosine synthase activity Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate. MetaCyc:RXN-7461|EC:2.5.1.52|RHEA:12693|KEGG_REACTION:R04091 go-plus.json 3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity|O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity|O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)|O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity http://purl.obolibrary.org/obo/GO_0050461 GO:0050477 biolink:MolecularActivity acyl-lysine deacylase activity Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate. EC:3.5.1.17|RHEA:24548|MetaCyc:ACYL-LYSINE-DEACYLASE-RXN go-plus.json 6-N-acyl-L-lysine amidohydrolase activity|epsilon-lysine acylase activity|N6-acyl-L-lysine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050477 GO:0050478 biolink:MolecularActivity obsolete anthranilate 3-monooxygenase activity OBSOLETE. Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O. go-plus.json anthranilate 3-hydroxylase activity|anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|anthranilic acid hydroxylase activity http://purl.obolibrary.org/obo/GO_0050478 GO:0050475 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050475 GO:0050476 biolink:MolecularActivity acetylenedicarboxylate decarboxylase activity Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate. MetaCyc:4.1.1.78-RXN|EC:4.1.1.78|RHEA:17733 go-plus.json acetylenedicarboxylate hydratase activity|acetylenedicarboxylate carboxy-lyase (pyruvate-forming)|acetylenedicarboxylate hydrase activity|acetylenedicarboxylate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0050476 GO:0050479 biolink:MolecularActivity glyceryl-ether monooxygenase activity Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine). EC:1.14.16.5|MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN|Reactome:R-HSA-5696119|RHEA:36255 go-plus.json alkylglycerol monooxygenase activity|glyceryl etherase activity|O-alkylglycerol monooxygenase activity|1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity|glyceryl ether oxygenase activity|glyceryl-ether cleaving enzyme activity http://purl.obolibrary.org/obo/GO_0050479 GO:1902229 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway in response to DNA damage Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage. go-plus.json regulation of DNA damage response, signal transduction resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_1902229 GO:1902227 biolink:BiologicalProcess negative regulation of macrophage colony-stimulating factor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway. go-plus.json down-regulation of M-CSF signaling pathway|negative regulation of M-CSF signaling pathway|inhibition of macrophage colony-stimulating factor signalling pathway|inhibition of M-CSF signaling pathway|down regulation of macrophage colony-stimulating factor signalling pathway|down-regulation of macrophage colony-stimulating factor signaling pathway|downregulation of macrophage colony-stimulating factor signalling pathway|down regulation of M-CSF signaling pathway|downregulation of M-CSF signaling pathway|downregulation of macrophage colony-stimulating factor signaling pathway|down-regulation of macrophage colony-stimulating factor signalling pathway|negative regulation of macrophage colony-stimulating factor signalling pathway|down regulation of macrophage colony-stimulating factor signaling pathway|inhibition of macrophage colony-stimulating factor signaling pathway http://purl.obolibrary.org/obo/GO_1902227 GO:1902228 biolink:BiologicalProcess positive regulation of macrophage colony-stimulating factor signaling pathway Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway. go-plus.json upregulation of macrophage colony-stimulating factor signaling pathway|up-regulation of macrophage colony-stimulating factor signalling pathway|up-regulation of M-CSF signaling pathway|up-regulation of macrophage colony-stimulating factor signaling pathway|activation of macrophage colony-stimulating factor signaling pathway|upregulation of macrophage colony-stimulating factor signalling pathway|upregulation of M-CSF signaling pathway|up regulation of macrophage colony-stimulating factor signalling pathway|up regulation of macrophage colony-stimulating factor signaling pathway|positive regulation of macrophage colony-stimulating factor signalling pathway|activation of macrophage colony-stimulating factor signalling pathway|up regulation of M-CSF signaling pathway|positive regulation of M-CSF signaling pathway|activation of M-CSF signaling pathway http://purl.obolibrary.org/obo/GO_1902228 GO:1902225 biolink:BiologicalProcess negative regulation of acrosome reaction Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction. go-plus.json down-regulation of acrosome reaction|inhibition of acrosome reaction|down regulation of acrosome reaction|downregulation of acrosome reaction http://purl.obolibrary.org/obo/GO_1902225 CL:0000338 biolink:Cell neuroblast (sensu Nematoda and Protostomia) go-plus.json neuroblast http://purl.obolibrary.org/obo/CL_0000338 CL:0000339 biolink:Cell glioblast (sensu Vertebrata) An early neural cell developing from the early ependymal cell of the neural tube. go-plus.json spongioblast http://purl.obolibrary.org/obo/CL_0000339 GO:1902226 biolink:BiologicalProcess regulation of macrophage colony-stimulating factor signaling pathway Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway. go-plus.json regulation of macrophage colony-stimulating factor signalling pathway|regulation of M-CSF signaling pathway http://purl.obolibrary.org/obo/GO_1902226 GO:1902223 biolink:BiologicalProcess erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid. go-plus.json erythrose 4-phosphate/phosphoenolpyruvate family amino acid formation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthesis|erythrose 4-phosphate/phosphoenolpyruvate family amino acid anabolism|erythrose 4-phosphate/phosphoenolpyruvate family amino acid synthesis http://purl.obolibrary.org/obo/GO_1902223 GO:1902224 biolink:BiologicalProcess ketone body metabolic process The chemical reactions and pathways involving ketone body. go-plus.json ketone body metabolism http://purl.obolibrary.org/obo/GO_1902224 GO:1902221 biolink:BiologicalProcess erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid. go-plus.json erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism http://purl.obolibrary.org/obo/GO_1902221 GO:1902222 biolink:BiologicalProcess erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid. go-plus.json erythrose 4-phosphate/phosphoenolpyruvate family amino acid degradation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid breakdown|erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolism http://purl.obolibrary.org/obo/GO_1902222 GO:1902230 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage. go-plus.json down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|inhibition of DNA damage response, signal transduction resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage|down-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage|downregulation of DNA damage response, signal transduction resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage|down regulation of DNA damage response, signal transduction resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_1902230 GO:1902231 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage. go-plus.json up-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|activation of DNA damage response, signal transduction resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage|activation of intrinsic apoptotic signaling pathway in response to DNA damage|upregulation of DNA damage response, signal transduction resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_1902231 CL:0000333 biolink:Cell migratory neural crest cell A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. go-plus.json http://purl.obolibrary.org/obo/CL_0000333 GO:0050470 biolink:MolecularActivity trimethylamine dehydrogenase activity Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein. UM-BBD_enzymeID:e0854|MetaCyc:1.5.8.2-RXN|RHEA:11864|EC:1.5.8.2 go-plus.json trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)|TMADh activity http://purl.obolibrary.org/obo/GO_0050470 GO:0050473 biolink:MolecularActivity arachidonate 15-lipoxygenase activity Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate. Reactome:R-HSA-9028255|Reactome:R-HSA-2162002|Reactome:R-HSA-9018907|EC:1.13.11.33|Reactome:R-HSA-9020262|Reactome:R-HSA-2161951|Reactome:R-HSA-9020610|Reactome:R-HSA-9027607|Reactome:R-HSA-9026003|Reactome:R-HSA-9024881|Reactome:R-HSA-9020275|Reactome:R-HSA-9025152|RHEA:16869|Reactome:R-HSA-9024872|MetaCyc:ARACHIDONATE-15-LIPOXYGENASE-RXN|Reactome:R-HSA-9027532|Reactome:R-HSA-9027627|Reactome:R-HSA-9020261 go-plus.json linoleic acid omega6-lipoxygenase activity|15-lipoxygenase activity|arachidonate omega(6) lipoxygenase activity|omega6 lipoxygenase activity|arachidonate omega6 lipoxygenase activity|arachidonate:oxygen 15-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050473 GO:0050474 biolink:MolecularActivity (S)-norcoclaurine synthase activity Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O. RHEA:16173|MetaCyc:S-NORLAUDANOSOLINE-SYNTHASE-RXN|EC:4.2.1.78 go-plus.json (S)-norlaudanosoline synthase activity|4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]|4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine) http://purl.obolibrary.org/obo/GO_0050474 GO:0050471 biolink:MolecularActivity uracilylalanine synthase activity Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate. MetaCyc:URACILYLALANINE-SYNTHASE-RXN|EC:2.5.1.53|RHEA:11496 go-plus.json O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity|Willardiine synthase activity|3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|isowillardiine synthase activity|O3-acetyl-L-serine acetate-lyase (adding uracil) http://purl.obolibrary.org/obo/GO_0050471 CHEBI:52582 biolink:ChemicalSubstance isobacteriochlorins go-plus.json http://purl.obolibrary.org/obo/CHEBI_52582 GO:0050472 biolink:MolecularActivity zeatin reductase activity Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin. MetaCyc:ZEATIN-REDUCTASE-RXN|EC:1.3.1.69|RHEA:12757|KEGG_REACTION:R05702 go-plus.json dihydrozeatin:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050472 GO:0050488 biolink:MolecularActivity ecdysteroid UDP-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid. go-plus.json ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity http://purl.obolibrary.org/obo/GO_0050488 GO:0050489 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050489 GO:0050486 biolink:MolecularActivity intramolecular transferase activity, transferring hydroxy groups Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule. EC:5.4.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0050486 GO:0050487 biolink:MolecularActivity sulfoacetaldehyde acetyltransferase activity Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde. RHEA:24204|KEGG_REACTION:R05651|MetaCyc:RXN-2364|EC:2.3.3.15 go-plus.json sulphoacetaldehyde acetyltransferase activity|acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming) http://purl.obolibrary.org/obo/GO_0050487 GO:1902238 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. go-plus.json http://purl.obolibrary.org/obo/GO_1902238 GO:1902239 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. go-plus.json inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator http://purl.obolibrary.org/obo/GO_1902239 GO:1902236 biolink:BiologicalProcess negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. go-plus.json downregulation of apoptosis in response to ER stress|down-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|negative regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down regulation of ER stress-induced apoptosis|down regulation of endoplasmic reticulum stress-induced apoptosis|down regulation of apoptosis triggered by ER stress|down regulation of apoptosis in response to ER stress|inhibition of endoplasmic reticulum stress-induced apoptosis|inhibition of apoptosis triggered by ER stress|inhibition of apoptosis in response to ER stress|downregulation of ER stress-induced apoptosis|inhibition of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of ER stress-induced apoptosis|negative regulation of ER stress-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced apoptosis|negative regulation of endoplasmic reticulum stress-induced apoptosis|negative regulation of apoptosis triggered by ER stress|down-regulation of apoptosis triggered by ER stress|inhibition of ER stress-induced apoptosis|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of apoptosis in response to ER stress|negative regulation of apoptosis in response to ER stress|downregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|inhibition of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of endoplasmic reticulum stress-induced apoptosis|downregulation of apoptosis triggered by ER stress http://purl.obolibrary.org/obo/GO_1902236 GO:1902237 biolink:BiologicalProcess positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. go-plus.json upregulation of ER stress-induced apoptosis|upregulation of endoplasmic reticulum stress-induced apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of apoptosis triggered by ER stress|upregulation of apoptosis in response to ER stress|up-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up regulation of ER stress-induced apoptosis|activation of ER stress-induced apoptosis|positive regulation of ER stress-induced apoptosis|activation of endoplasmic reticulum stress-induced apoptosis|up-regulation of endoplasmic reticulum stress-induced apoptosis|activation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up-regulation of apoptosis triggered by ER stress|activation of apoptosis in response to ER stress|up-regulation of apoptosis in response to ER stress|activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up-regulation of ER stress-induced apoptosis|positive regulation of endoplasmic reticulum stress-induced apoptosis|positive regulation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|positive regulation of apoptosis in response to ER stress|up regulation of endoplasmic reticulum stress-induced apoptosis|activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up regulation of apoptosis triggered by ER stress|positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up regulation of apoptosis in response to ER stress http://purl.obolibrary.org/obo/GO_1902237 CL:0000306 biolink:Cell crystallin accumulating cell go-plus.json lens cell http://purl.obolibrary.org/obo/CL_0000306 GO:1902234 biolink:BiologicalProcess positive regulation of positive thymic T cell selection Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection. go-plus.json upregulation of positive thymic T-lymphocyte selection|positive regulation of positive thymic T lymphocyte selection|up regulation of positive thymic T lymphocyte selection|up-regulation of positive thymic T-cell selection|activation of positive thymic T-cell selection|up-regulation of positive thymic T-lymphocyte selection|upregulation of positive thymic T cell selection|activation of positive thymic T-lymphocyte selection|upregulation of positive thymic T lymphocyte selection|positive regulation of positive thymic T-cell selection|up regulation of positive thymic T-cell selection|up-regulation of positive thymic T cell selection|activation of positive thymic T cell selection|positive regulation of positive thymic T-lymphocyte selection|up regulation of positive thymic T-lymphocyte selection|up-regulation of positive thymic T lymphocyte selection|activation of positive thymic T lymphocyte selection|upregulation of positive thymic T-cell selection|up regulation of positive thymic T cell selection http://purl.obolibrary.org/obo/GO_1902234 GO:1902235 biolink:BiologicalProcess regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. go-plus.json regulation of endoplasmic reticulum stress-induced apoptosis|regulation of apoptosis triggered by ER stress|regulation of apoptosis in response to ER stress|regulation of ER stress-induced apoptosis|regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of apoptosis in response to endoplasmic reticulum stress|regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_1902235 GO:1902232 biolink:BiologicalProcess regulation of positive thymic T cell selection Any process that modulates the frequency, rate or extent of positive thymic T cell selection. go-plus.json regulation of positive thymic T lymphocyte selection|regulation of positive thymic T-cell selection|regulation of positive thymic T-lymphocyte selection http://purl.obolibrary.org/obo/GO_1902232 GO:1902233 biolink:BiologicalProcess negative regulation of positive thymic T cell selection Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection. go-plus.json downregulation of positive thymic T cell selection|down regulation of positive thymic T cell selection|downregulation of positive thymic T lymphocyte selection|inhibition of positive thymic T cell selection|down regulation of positive thymic T lymphocyte selection|inhibition of positive thymic T lymphocyte selection|negative regulation of positive thymic T-cell selection|down-regulation of positive thymic T-cell selection|negative regulation of positive thymic T-lymphocyte selection|down-regulation of positive thymic T-lymphocyte selection|downregulation of positive thymic T-cell selection|downregulation of positive thymic T-lymphocyte selection|down-regulation of positive thymic T cell selection|down regulation of positive thymic T-cell selection|inhibition of positive thymic T-cell selection|down-regulation of positive thymic T lymphocyte selection|down regulation of positive thymic T-lymphocyte selection|negative regulation of positive thymic T lymphocyte selection|inhibition of positive thymic T-lymphocyte selection http://purl.obolibrary.org/obo/GO_1902233 GO:1902241 biolink:BiologicalProcess copal-8-ol diphosphate(3-) metabolic process The chemical reactions and pathways involving copal-8-ol diphosphate(3-). go-plus.json copal-8-ol diphosphate(3-) metabolism http://purl.obolibrary.org/obo/GO_1902241 GO:1902242 biolink:BiologicalProcess copal-8-ol diphosphate(3-) catabolic process The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-). go-plus.json copal-8-ol diphosphate(3-) degradation|copal-8-ol diphosphate(3-) breakdown|copal-8-ol diphosphate(3-) catabolism http://purl.obolibrary.org/obo/GO_1902242 GO:1902240 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. go-plus.json up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator http://purl.obolibrary.org/obo/GO_1902240 CL:0000300 biolink:Cell gamete A mature sexual reproductive cell having a single set of unpaired chromosomes. go-plus.json haploid germ cell|haploid nucleated cell http://purl.obolibrary.org/obo/CL_0000300 CL:0000301 biolink:Cell pole cell go-plus.json http://purl.obolibrary.org/obo/CL_0000301 GO:0050480 biolink:MolecularActivity imidazolonepropionase activity Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+). EC:3.5.2.7|KEGG_REACTION:R02288|MetaCyc:IMIDAZOLONEPROPIONASE-RXN|RHEA:23660 go-plus.json imidazolone propionic acid hydrolase activity|imidazolone-5-propionate hydrolase activity|4(5)-imidazolone-5(4)-propionic acid hydrolase activity|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050480 GO:0050481 biolink:MolecularActivity mandelate 4-monooxygenase activity Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate. KEGG_REACTION:R03794|EC:1.14.16.6|RHEA:21716|MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN go-plus.json L-mandelate 4-hydroxylase activity|mandelic acid 4-hydroxylase activity|(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) http://purl.obolibrary.org/obo/GO_0050481 CHEBI:52575 biolink:ChemicalSubstance alkylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52575 GO:0050484 biolink:MolecularActivity GMP 5'-nucleotidase activity Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate. RHEA:27714|MetaCyc:RXN-7609 go-plus.json IMP-GMP specific 5'-nucleotidase activity|GMP 5' nucleotidase activity http://purl.obolibrary.org/obo/GO_0050484 CHEBI:52570 biolink:ChemicalSubstance alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_52570 chebi_ph7_3 GO:0050485 biolink:MolecularActivity oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide. EC:1.21.4.- go-plus.json oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor http://purl.obolibrary.org/obo/GO_0050485 GO:0050482 biolink:BiologicalProcess arachidonic acid secretion The controlled release of arachidonic acid from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0050482 CHEBI:52572 biolink:ChemicalSubstance acylglucosaminylphosphatidylinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52572 GO:0050483 biolink:MolecularActivity IMP 5'-nucleotidase activity Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate. MetaCyc:RXN-7607|RHEA:27718 go-plus.json IMP-GMP specific 5'-nucleotidase activity|IMP 5' nucleotidase activity http://purl.obolibrary.org/obo/GO_0050483 GO:0050499 biolink:MolecularActivity oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H. EC:1.20.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0050499 GO:0050497 biolink:MolecularActivity alkylthioltransferase activity Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor). EC:2.8.4.- go-plus.json transferase activity, transferring alkylthio groups http://purl.obolibrary.org/obo/GO_0050497 GO:0050498 biolink:MolecularActivity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated. EC:1.14.20.- go-plus.json http://purl.obolibrary.org/obo/GO_0050498 NCBITaxon:687453 biolink:OrganismalEntity Platacanthomyidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_687453 CHEBI:52567 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52567 NCBITaxon:687454 biolink:OrganismalEntity Typhlomys go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_687454 CHEBI:52569 biolink:ChemicalSubstance 1-(alk-1-enyl)glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52569 chebi_ph7_3 CL:0000314 biolink:Cell milk secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000314 GO:1902249 biolink:MolecularActivity IMP binding Binding to IMP, inosine monophosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1902249 GO:1902247 biolink:BiologicalProcess geranylgeranyl diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate. go-plus.json geranylgeranyl diphosphate catabolism|geranylgeranyl diphosphate degradation|geranylgeranyl diphosphate breakdown http://purl.obolibrary.org/obo/GO_1902247 GO:1902248 biolink:MolecularActivity 5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding Binding to 5-O-phosphono-alpha-D-ribofuranosyl diphosphate. go-plus.json phosphoribosylpyrophosphate binding|5-phosphoribose 1-diphosphate binding http://purl.obolibrary.org/obo/GO_1902248 CL:0000317 biolink:Cell sebum secreting cell A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris. go-plus.json sebocyte http://purl.obolibrary.org/obo/CL_0000317 GO:1902245 biolink:BiologicalProcess cis-abienol catabolic process The chemical reactions and pathways resulting in the breakdown of cis-abienol. go-plus.json cis-abienol degradation|cis-abienol breakdown|cis-abienol catabolism http://purl.obolibrary.org/obo/GO_1902245 CL:0000319 biolink:Cell mucus secreting cell go-plus.json mucous cell http://purl.obolibrary.org/obo/CL_0000319 GO:1902246 biolink:BiologicalProcess cis-abienol biosynthetic process The chemical reactions and pathways resulting in the formation of cis-abienol. go-plus.json cis-abienol anabolism|cis-abienol synthesis|cis-abienol formation|cis-abienol biosynthesis http://purl.obolibrary.org/obo/GO_1902246 GO:1902243 biolink:BiologicalProcess copal-8-ol diphosphate(3-) biosynthetic process The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-). go-plus.json copal-8-ol diphosphate(3-) anabolism|copal-8-ol diphosphate(3-) synthesis|copal-8-ol diphosphate(3-) formation|copal-8-ol diphosphate(3-) biosynthesis http://purl.obolibrary.org/obo/GO_1902243 GO:1902244 biolink:BiologicalProcess cis-abienol metabolic process The chemical reactions and pathways involving cis-abienol. go-plus.json cis-abienol metabolism http://purl.obolibrary.org/obo/GO_1902244 GO:1902252 biolink:BiologicalProcess positive regulation of erythrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process. go-plus.json up regulation of erythrocyte apoptosis|positive regulation of red blood cell apoptotic process|positive regulation of erythrocyte apoptosis|up regulation of red blood cell apoptotic process|up-regulation of RBC apoptotic process|up regulation of erythrocyte apoptotic process|activation of erythrocyte apoptosis|activation of erythrocyte apoptotic process|upregulation of RBC apoptosis|upregulation of red blood cell apoptosis|upregulation of RBC apoptotic process|upregulation of red blood cell apoptotic process|up-regulation of erythrocyte apoptosis|up-regulation of red blood cell apoptosis|up regulation of RBC apoptosis|positive regulation of RBC apoptosis|up-regulation of erythrocyte apoptotic process|up-regulation of red blood cell apoptotic process|activation of red blood cell apoptotic process|upregulation of erythrocyte apoptosis|activation of red blood cell apoptosis|up regulation of RBC apoptotic process|activation of RBC apoptotic process|activation of RBC apoptosis|positive regulation of RBC apoptotic process|positive regulation of red blood cell apoptosis|upregulation of erythrocyte apoptotic process|up regulation of red blood cell apoptosis|up-regulation of RBC apoptosis http://purl.obolibrary.org/obo/GO_1902252 GO:1902253 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway by p53 class mediator Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. go-plus.json regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator http://purl.obolibrary.org/obo/GO_1902253 GO:1902250 biolink:BiologicalProcess regulation of erythrocyte apoptotic process Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process. go-plus.json regulation of red blood cell apoptosis|regulation of red blood cell apoptotic process|regulation of RBC apoptosis|regulation of RBC apoptotic process|regulation of erythrocyte apoptosis http://purl.obolibrary.org/obo/GO_1902250 GO:1902251 biolink:BiologicalProcess negative regulation of erythrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process. go-plus.json downregulation of red blood cell apoptosis|downregulation of erythrocyte apoptotic process|inhibition of RBC apoptosis|inhibition of RBC apoptotic process|down regulation of red blood cell apoptosis|downregulation of red blood cell apoptotic process|down-regulation of erythrocyte apoptosis|negative regulation of erythrocyte apoptosis|down regulation of red blood cell apoptotic process|down regulation of RBC apoptosis|inhibition of red blood cell apoptotic process|down-regulation of erythrocyte apoptotic process|inhibition of red blood cell apoptosis|downregulation of RBC apoptosis|down regulation of RBC apoptotic process|inhibition of erythrocyte apoptotic process|inhibition of erythrocyte apoptosis|downregulation of RBC apoptotic process|negative regulation of red blood cell apoptosis|down-regulation of RBC apoptosis|down-regulation of red blood cell apoptosis|negative regulation of RBC apoptosis|down regulation of erythrocyte apoptosis|negative regulation of RBC apoptotic process|negative regulation of red blood cell apoptotic process|down-regulation of red blood cell apoptotic process|down-regulation of RBC apoptotic process|downregulation of erythrocyte apoptosis|down regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902251 CL:0000311 biolink:Cell keratin accumulating cell go-plus.json http://purl.obolibrary.org/obo/CL_0000311 CL:0000312 biolink:Cell keratinocyte An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. go-plus.json malpighian cell|keratinized cell of epidermis http://purl.obolibrary.org/obo/CL_0000312 GO:0050491 biolink:MolecularActivity sulcatone reductase activity Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone. EC:1.1.1.260|KEGG_REACTION:R05678|RHEA:24484|MetaCyc:1.1.1.260-RXN go-plus.json sulcatol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050491 GO:0050492 biolink:MolecularActivity glycerol-1-phosphate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate. EC:1.1.1.261|MetaCyc:1.1.1.261-RXN go-plus.json sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050492 CHEBI:52564 biolink:ChemicalSubstance 2-carboxy-4-methyl-5-[(2-phosphonooxy)ethylidene]-2,5-dihydrothiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_52564 GO:0050490 biolink:MolecularActivity 1,4-lactonase activity Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid. EC:3.1.1.25|MetaCyc:14-LACTONASE-RXN|RHEA:12745 go-plus.json 1,4-lactone hydroxyacylhydrolase activity|gamma-lactonase activity http://purl.obolibrary.org/obo/GO_0050490 CHEBI:52565 biolink:ChemicalSubstance acylglycerophosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52565 GO:0050495 biolink:BiologicalProcess peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine. RESID:AA0346 go-plus.json peptidyl-glycyl-phosphatidylethanolamine synthesis from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine formation from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine anabolism from peptidyl-glycine http://purl.obolibrary.org/obo/GO_0050495 GO:0050496 biolink:BiologicalProcess peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide. RESID:AA0340 go-plus.json peptidyl-L-glutamyl 5-omega-hydroxyceramide ester anabolism from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester synthesis from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester formation from peptidyl-glutamine http://purl.obolibrary.org/obo/GO_0050496 GO:0050493 biolink:BiologicalProcess GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0164 go-plus.json GPI anchor anabolism via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-threonyl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0050493 GO:0050494 biolink:BiologicalProcess GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0165 go-plus.json GSI anchor anabolism via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor synthesis via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor formation via N-glycyl-glycosylsphingolipidinositolethanolamine http://purl.obolibrary.org/obo/GO_0050494 CHEBI:76526 biolink:ChemicalSubstance 6-oxocyclohex-1-ene-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76526 chebi_ph7_3 CHEBI:76527 biolink:ChemicalSubstance 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76527 chebi_ph7_3 CHEBI:76524 biolink:ChemicalSubstance (3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76524 CHEBI:76529 biolink:ChemicalSubstance glycerophosphoglycerophosphoglycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76529 chebi_ph7_3 CHEBI:76522 biolink:ChemicalSubstance (3R,15Z)-3-hydroxytetracosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76522 CHEBI:76523 biolink:ChemicalSubstance (2E,15Z)-tetracosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76523 CHEBI:76520 biolink:ChemicalSubstance (2E,13Z)-docosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76520 UBERON:0010091 biolink:AnatomicalEntity future hindbrain meninx A multi-tissue structure that has the potential to develop into a meninx of hindbrain. go-plus.json future hindbrain meninges http://purl.obolibrary.org/obo/UBERON_0010091 CHEBI:76538 biolink:ChemicalSubstance (2E,8Z,11Z,14Z)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76538 CHEBI:76535 biolink:ChemicalSubstance [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n go-plus.json http://purl.obolibrary.org/obo/CHEBI_76535 CHEBI:76536 biolink:ChemicalSubstance (3R,8Z,11Z,14Z)-3-hydroxyicosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76536 CHEBI:76539 biolink:ChemicalSubstance [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n (1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76539 chebi_ph7_3 UBERON:0010092 biolink:AnatomicalEntity future metencephalon A developing anatomical structure that has the potential to develop into a metencephalon. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010092 UBERON:0010096 biolink:AnatomicalEntity future myelencephalon A developing anatomical structure that has the potential to develop into a myelencephalon. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010096 CHEBI:76530 biolink:ChemicalSubstance sn-glycero-3-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76530 chebi_ph7_3 PR:000000105 biolink:Protein nodal protein A TGF-beta-like cystine-knot cytokine that is a translation product of the human NODAL gene or a 1:1 ortholog thereof. The nodal and lefty genes form positive and negative regulatory loops that resemble the reaction-diffusion system. As a pair, these genes control various events of vertebrate embryonic patterning, including left-right specification and mesoderm formation. go-plus.json NODAL http://purl.obolibrary.org/obo/PR_000000105 CHEBI:76533 biolink:ChemicalSubstance NDP-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76533 chebi_ph7_3 CHEBI:76534 biolink:ChemicalSubstance (11Z,14Z)-icosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76534 CHEBI:76532 biolink:ChemicalSubstance (2E,11Z,14Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76532 CHEBI:76548 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z)-3-oxohexacosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76548 CHEBI:76549 biolink:ChemicalSubstance (3R,11Z,14Z,17Z,20Z)-3-hydroxyhexacosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76549 CHEBI:76547 biolink:ChemicalSubstance (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76547 UBERON:0010083 biolink:AnatomicalEntity future dermis Mesenchyme that has the potential to develop into a dermis. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010083 UBERON:0010084 biolink:AnatomicalEntity future diaphragm A structure that will develop into a diaphragm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010084 UBERON:0010081 biolink:AnatomicalEntity future common hepatic duct An extrahepatic bile duct that has the potential to develop into a common hepatic duct. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010081 UBERON:0009097 biolink:AnatomicalEntity gravid organism An organism containing a developing embryo, fetus, or unborn offspring within the body. go-plus.json pregnant stage|gravid|pregnant adult|pregnant organism|pregnant adult stage http://purl.obolibrary.org/obo/UBERON_0009097 UBERON:0009098 biolink:AnatomicalEntity gravid uterus The uterus in pregnancy go-plus.json womb http://purl.obolibrary.org/obo/UBERON_0009098 CHEBI:76541 biolink:ChemicalSubstance (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76541 CHEBI:76545 biolink:ChemicalSubstance 2-iminobutanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76545 chebi_ph7_3 CHEBI:76542 biolink:ChemicalSubstance (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76542 CHEBI:76543 biolink:ChemicalSubstance (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76543 CHEBI:76559 biolink:ChemicalSubstance (13Z)-3-oxoicosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76559 chebi_ph7_3 CHEBI:76557 biolink:ChemicalSubstance (3R,11Z)-3-hydroxyoctadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76557 chebi_ph7_3 CHEBI:76558 biolink:ChemicalSubstance (2E,11Z)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76558 chebi_ph7_3 UBERON:0010070 biolink:AnatomicalEntity intermediate layer of tympanic membrane The intermediate fibrous layer of the tympanic membrane. go-plus.json intermediate fibrous layer of tympanic membrane|connective tissue layer of tympanic membrane|fibrous layer of tympanic membrane|fibrous stratum of tympanic membrane|tympanic endothelium http://purl.obolibrary.org/obo/UBERON_0010070 UBERON:0010071 biolink:AnatomicalEntity layer of tympanic membrane go-plus.json tympanic membrane layer http://purl.obolibrary.org/obo/UBERON_0010071 UBERON:0010076 biolink:AnatomicalEntity network of trabecular spaces in bone tissue Tissue cavity consisting of intercommunicating trabecular spaces in the cancellous bone. go-plus.json trabecular space network|trabecular network of bone tissue http://purl.obolibrary.org/obo/UBERON_0010076 UBERON:0010077 biolink:AnatomicalEntity cuboidal epithelium An epithelium consisting of cuboidal epithelial cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010077 UBERON:0010074 biolink:AnatomicalEntity chromaffin system Organ system subdivision that consists primarily of chromaffin cells and their supporting structures. go-plus.json argentaffin system|chromaffin tissue http://purl.obolibrary.org/obo/UBERON_0010074 UBERON:0010075 biolink:AnatomicalEntity sacral neural crest One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010075 PR:000014717 biolink:Protein protein SET A protein that is a translation product of the human SET gene or a 1:1 ortholog thereof. go-plus.json PHAPII|IGAAD|SET|I-2PP2A|TAF-I|template-activating factor I|inhibitor of granzyme A-activated DNase|HLA-DR-associated protein II|phosphatase 2A inhibitor I2PP2A http://purl.obolibrary.org/obo/PR_000014717 CHEBI:76552 biolink:ChemicalSubstance (9Z,12Z)-hexadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76552 chebi_ph7_3 CHEBI:76550 biolink:ChemicalSubstance (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76550 CHEBI:76555 biolink:ChemicalSubstance (11Z)-3-oxooctadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76555 chebi_ph7_3 CHEBI:76556 biolink:ChemicalSubstance (3R,15Z,18Z,21Z,24Z)-3-hydroxytriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76556 CHEBI:76553 biolink:ChemicalSubstance (3R,13Z,16Z,19Z,22Z)-3-hydroxyoctacosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76553 CHEBI:76554 biolink:ChemicalSubstance (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76554 GO:1990794 biolink:CellularComponent basolateral part of cell The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990794 GO:1990795 biolink:CellularComponent rod bipolar cell terminal bouton A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer. go-plus.json http://purl.obolibrary.org/obo/GO_1990795 GO:1990796 biolink:CellularComponent photoreceptor cell terminal bouton A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light. go-plus.json http://purl.obolibrary.org/obo/GO_1990796 CHEBI:76568 biolink:ChemicalSubstance (3R,19Z,22Z,25Z,28Z)-3-hydroxytetratriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76568 CHEBI:76569 biolink:ChemicalSubstance (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76569 GO:1990797 biolink:BiologicalProcess obsolete cholecystokinin secretion OBSOLETE. The controlled release of cholecystokinin from a cell. Cholecystokinin is a peptide hormone that participates in pancreatic enzyme release in the gut and is also found in the brain. go-plus.json CCK secretion http://purl.obolibrary.org/obo/GO_1990797 GO:1990790 biolink:BiologicalProcess response to glial cell derived neurotrophic factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus. go-plus.json response to ATF|response to astrocyte-derived trophic factor|response to GDNF http://purl.obolibrary.org/obo/GO_1990790 GO:1990791 biolink:BiologicalProcess dorsal root ganglion development The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure. go-plus.json DRG development http://purl.obolibrary.org/obo/GO_1990791 GO:1990792 biolink:BiologicalProcess cellular response to glial cell derived neurotrophic factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus. go-plus.json cellular response to astrocyte-derived trophic factor|cellular response to GDNF|cellular response to ATF http://purl.obolibrary.org/obo/GO_1990792 GO:1990793 biolink:BiologicalProcess substance P secretion, neurotransmission The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_1990793 UBERON:6000002 biolink:AnatomicalEntity panarthropod tagma The three main divisions of the whole organism formed from groups of segments. go-plus.json http://purl.obolibrary.org/obo/UBERON_6000002 UBERON:6000006 biolink:AnatomicalEntity head segment Any segment that is part of some head. go-plus.json http://purl.obolibrary.org/obo/UBERON_6000006 UBERON:6000004 biolink:AnatomicalEntity panarthropod head go-plus.json http://purl.obolibrary.org/obo/UBERON_6000004 CHEBI:76562 biolink:ChemicalSubstance (2E,13Z)-icosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76562 chebi_ph7_3 CHEBI:76563 biolink:ChemicalSubstance (13Z)-icosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76563 chebi_ph7_3 CHEBI:76560 biolink:ChemicalSubstance (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76560 CHEBI:76561 biolink:ChemicalSubstance (3R,13Z)-3-hydroxyicosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76561 chebi_ph7_3 GO:1990798 biolink:BiologicalProcess pancreas regeneration The regrowth of a destroyed pancreas. go-plus.json http://purl.obolibrary.org/obo/GO_1990798 CHEBI:76566 biolink:ChemicalSubstance (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76566 GO:1990799 biolink:BiologicalProcess mitochondrial tRNA wobble position uridine thiolation The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. go-plus.json http://purl.obolibrary.org/obo/GO_1990799 CHEBI:76567 biolink:ChemicalSubstance polyunsaturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76567 CHEBI:76564 biolink:ChemicalSubstance (3R,17Z,20Z,23Z,26Z)-3-hydroxydotriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76564 CHEBI:76565 biolink:ChemicalSubstance 2-ammonioprop-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76565 chebi_ph7_3 CHEBI:76579 biolink:ChemicalSubstance triradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76579 CHEBI:76570 biolink:ChemicalSubstance (3R,21Z,24Z,27Z,30Z)-3-hydroxyhexatriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76570 CHEBI:76571 biolink:ChemicalSubstance (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76571 CHEBI:76578 biolink:ChemicalSubstance diradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76578 CHEBI:76575 biolink:ChemicalSubstance monoradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76575 GO:0050400 biolink:MolecularActivity xylitol kinase activity Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate. RHEA:20209|KEGG_REACTION:R02136|MetaCyc:XYLITOL-KINASE-RXN|EC:2.7.1.122 go-plus.json xylitol phosphotransferase activity|ATP:xylitol 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050400 GO:0050401 biolink:MolecularActivity xylonate dehydratase activity Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O. KEGG_REACTION:R02429|EC:4.2.1.82|MetaCyc:XYLONATE-DEHYDRATASE-RXN|RHEA:19157 go-plus.json D-xylonate hydro-lyase activity|D-xylo-aldonate dehydratase activity|D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)|D-xylonate dehydratase activity http://purl.obolibrary.org/obo/GO_0050401 GO:0050404 biolink:MolecularActivity zeatin O-beta-D-xylosyltransferase activity Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP. KEGG_REACTION:R02119|MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN|RHEA:14721|EC:2.4.2.40 go-plus.json zeatin O-b-D-xylosyltransferase activity|UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity|zeatin O-xylosyltransferase activity|uridine diphosphoxylose-zeatin xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0050404 GO:0050405 biolink:MolecularActivity [acetyl-CoA carboxylase] kinase activity Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate. RHEA:20333|MetaCyc:2.7.11.27-RXN|EC:2.7.11.27 go-plus.json acetyl-CoA carboxylase kinase (AMP-activated) activity|ATP:acetyl-CoA carboxylase phosphotransferase activity|acetyl coenzyme A carboxylase kinase (phosphorylating) activity|STK5|acetyl-coenzyme A carboxylase kinase activity|acetyl-CoA carboxylase kinase (cAMP-independent) activity|ACK3|ACK2|acetyl-CoA carboxylase bound kinase activity|AMPK|acetyl-CoA carboxylase kinase-2 activity|I-peptide kinase activity|acetyl-CoA carboxylase kinase activity|acetyl-CoA carboxylase kinase-3 (AMP-activated) activity|acetyl-CoA carboxylase kinase 2 activity http://purl.obolibrary.org/obo/GO_0050405 GO:0050402 biolink:MolecularActivity xylono-1,4-lactonase activity Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate. MetaCyc:XYLONO-14-LACTONASE-RXN|EC:3.1.1.68|RHEA:18341 go-plus.json xylonolactonase activity|D-xylono-1,4-lactone lactonohydrolase activity|xylono-g-lactonase activity http://purl.obolibrary.org/obo/GO_0050402 GO:0050403 biolink:MolecularActivity trans-zeatin O-beta-D-glucosyltransferase activity Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP. MetaCyc:RXN-4723|KEGG_REACTION:R02118|RHEA:23224|EC:2.4.1.203 go-plus.json UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity|zeatin O-b-D-glucosyltransferase activity|uridine diphosphoglucose-zeatin O-glucosyltransferase activity|UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity|zeatin O-glucosyltransferase activity|zeatin O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050403 GO:0050408 biolink:MolecularActivity [pyruvate kinase]-phosphatase activity Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate. EC:3.1.3.49|MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN go-plus.json pyruvate kinase phosphatase activity|ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity|pyruvate kinase-phosphatase activity http://purl.obolibrary.org/obo/GO_0050408 GO:0050409 biolink:MolecularActivity indolylacetylinositol arabinosyltransferase activity Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP. MetaCyc:2.4.2.34-RXN|EC:2.4.2.34|KEGG_REACTION:R04335|RHEA:19505 go-plus.json UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity|arabinosylindolylacetylinositol synthase activity|UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity http://purl.obolibrary.org/obo/GO_0050409 GO:0050406 biolink:MolecularActivity [acetyl-CoA carboxylase]-phosphatase activity Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate. MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN|EC:3.1.3.44|RHEA:17125 go-plus.json acetyl-CoA carboxylase-phosphatase activity|acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050406 GO:0050407 biolink:MolecularActivity [glycogen-synthase-D] phosphatase activity Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate. MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN|EC:3.1.3.42 go-plus.json UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|glycogen synthase phosphatase activity|uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity|glycogen-synthase-D phosphatase activity|glycogen synthase D phosphatase activity|UDPglucose-glycogen glucosyltransferase phosphatase activity|glycogen glucosyltransferase phosphatase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|phosphatase type 2oC|glycogen synthetase phosphatase activity|Mg2+ dependent glycogen synthase phosphatase activity|UDP-glycogen glucosyltransferase phosphatase activity http://purl.obolibrary.org/obo/GO_0050407 CL:0000385 biolink:Cell prohemocyte (sensu Nematoda and Protostomia) go-plus.json http://purl.obolibrary.org/obo/CL_0000385 CL:0000386 biolink:Cell attachment cell go-plus.json http://purl.obolibrary.org/obo/CL_0000386 CL:0000387 biolink:Cell hemocyte (sensu Arthropoda) go-plus.json http://purl.obolibrary.org/obo/CL_0000387 CL:0000388 biolink:Cell tendon cell An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance. go-plus.json tenocyte|muscle attachment cell http://purl.obolibrary.org/obo/CL_0000388 CHEBI:76581 biolink:ChemicalSubstance 2-alkylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76581 chebi_ph7_3 CHEBI:76584 biolink:ChemicalSubstance monoalkyldiacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76584 CHEBI:76585 biolink:ChemicalSubstance 1-alkyl-2,3-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76585 chebi_ph7_3 CHEBI:76582 biolink:ChemicalSubstance monoalkylmonoacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76582 CHEBI:76583 biolink:ChemicalSubstance alk-1-enylacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76583 CL:0000381 biolink:Cell neurosecretory neuron go-plus.json http://purl.obolibrary.org/obo/CL_0000381 GO:0050411 biolink:MolecularActivity agaritine gamma-glutamyltransferase activity Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor. EC:2.3.2.9|MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN go-plus.json (gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|agaritine g-glutamyltransferase activity http://purl.obolibrary.org/obo/GO_0050411 GO:0050412 biolink:MolecularActivity cinnamate beta-D-glucosyltransferase activity Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP. KEGG_REACTION:R02256|EC:2.4.1.177|MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN|RHEA:13437 go-plus.json UDPG:t-cinnamate glucosyltransferase activity|UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity|cinnamate b-D-glucosyltransferase activity|uridine diphosphoglucose-cinnamate glucosyltransferase activity|cinnamate glucosyltransferase activity|UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050412 GO:0050410 biolink:MolecularActivity 3-oxolaurate decarboxylase activity Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2). RHEA:13385|MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN|EC:4.1.1.56|KEGG_REACTION:R03747 go-plus.json 3-oxododecanoate carboxy-lyase (2-undecanone-forming)|beta-ketoacyl decarboxylase activity|3-oxododecanoate carboxy-lyase activity|beta-ketolaurate decarboxylase activity http://purl.obolibrary.org/obo/GO_0050410 GO:0050415 biolink:MolecularActivity formimidoylglutamase activity Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide. MetaCyc:FORMIMINOGLUTAMASE-RXN|EC:3.5.3.8|KEGG_REACTION:R02285|RHEA:22492 go-plus.json formiminoglutamase activity|N-formimidoyl-L-glutamate formimidoylhydrolase activity|N-formiminoglutamate hydrolase activity|formiminoglutamate hydrolase activity|N-formimino-L-glutamate formiminohydrolase activity http://purl.obolibrary.org/obo/GO_0050415 GO:0050416 biolink:MolecularActivity formimidoylglutamate deiminase activity Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3. EC:3.5.3.13|MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN|RHEA:22832 go-plus.json formiminoglutamic iminohydrolase activity|formiminoglutamate deiminase activity|N-formimidoyl-L-glutamate iminohydrolase activity http://purl.obolibrary.org/obo/GO_0050416 GO:0050413 biolink:MolecularActivity D-alanine 2-hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine. RHEA:10064|EC:2.1.2.7|MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN|KEGG_REACTION:R01225 go-plus.json 5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity|2-methylserine hydroxymethyltransferase activity|D-alanine hydroxymethyltransferase activity http://purl.obolibrary.org/obo/GO_0050413 GO:0050414 biolink:MolecularActivity formimidoylaspartate deiminase activity Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3. EC:3.5.3.5|RHEA:13661|MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN go-plus.json N-formimidoyl-L-aspartate iminohydrolase activity|formiminoaspartate deiminase activity http://purl.obolibrary.org/obo/GO_0050414 GO:0050419 biolink:MolecularActivity hydroxymandelonitrile lyase activity Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate. EC:4.1.2.11|RHEA:15977|MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN go-plus.json hydroxynitrile lyase activity|(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)|(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity|sorghum hydroxynitrile lyase activity http://purl.obolibrary.org/obo/GO_0050419 GO:0050417 biolink:MolecularActivity glutamin-(asparagin-)ase activity Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate. MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN|EC:3.5.1.38 go-plus.json L-ASNase/L-GLNase activity|L-asparagine/L-glutamine amidohydrolase activity|glutaminase-asparaginase activity|L-glutamine(L-asparagine) amidohydrolase activity|glutaminase-(asparagin-)ase activity http://purl.obolibrary.org/obo/GO_0050417 GO:0050418 biolink:MolecularActivity hydroxylamine reductase activity Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor. RHEA:22052|EC:1.7.99.1|MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN go-plus.json ammonia:(acceptor) oxidoreductase activity|hydroxylamine (acceptor) reductase activity|ammonia:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050418 CL:0000394 biolink:Cell plasmatocyte go-plus.json http://purl.obolibrary.org/obo/CL_0000394 CL:0000396 biolink:Cell lamellocyte go-plus.json http://purl.obolibrary.org/obo/CL_0000396 CL:0000397 biolink:Cell ganglion interneuron go-plus.json http://purl.obolibrary.org/obo/CL_0000397 CHEBI:76591 biolink:ChemicalSubstance (25R)-cholest-5-ene-3beta,26-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76591 chebi_ph7_3 CHEBI:76592 biolink:ChemicalSubstance (25R)-7alpha,26-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76592 chebi_ph7_3 CHEBI:76590 biolink:ChemicalSubstance 1-organyl-2-lyso-sn-glycero-3-phospholipid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76590 chebi_ph7_3 CHEBI:76595 biolink:ChemicalSubstance nephroprotective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_76595 CHEBI:76596 biolink:ChemicalSubstance ADP-D-ribose 1'',2''-cyclic phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76596 chebi_ph7_3 CHEBI:76593 biolink:ChemicalSubstance 1-acyl-2-[(Z)-9,10-enoyl]-sn-glycero-3-phospholipid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76593 chebi_ph7_3 CHEBI:76594 biolink:ChemicalSubstance 1-acyl-2-(9,10-methyleneacyl)-sn-glycero-3-phospholipid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76594 chebi_ph7_3 CL:0000390 biolink:Cell blood cell (sensu Nematoda and Protostomia) go-plus.json http://purl.obolibrary.org/obo/CL_0000390 CL:0000391 biolink:Cell podocyte (sensu Diptera) An insect immune cell that develops from plasmatocyte. go-plus.json http://purl.obolibrary.org/obo/CL_0000391 CL:0000392 biolink:Cell crystal cell go-plus.json http://purl.obolibrary.org/obo/CL_0000392 CL:0000393 biolink:Cell electrically responsive cell A cell whose function is determined by its response to an electric signal. go-plus.json http://purl.obolibrary.org/obo/CL_0000393 GO:1990750 biolink:CellularComponent obsolete axon shaft OBSOLETE. Main portion of an axon, excluding terminal, spines, or dendrites. go-plus.json axonal shaft http://purl.obolibrary.org/obo/GO_1990750 NCBITaxon:183924 biolink:OrganismalEntity Thermoprotei go-plus.json Crenarchaeota|Thermoprotea http://purl.obolibrary.org/obo/NCBITaxon_183924 CHEBI:27515 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-D-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_27515 GO:1990751 biolink:BiologicalProcess Schwann cell chemotaxis The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_1990751 CHEBI:27517 biolink:ChemicalSubstance (1->2)-beta-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27517 chebi_ph7_3 GO:1990752 biolink:CellularComponent microtubule end Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end. go-plus.json http://purl.obolibrary.org/obo/GO_1990752 GO:1990753 biolink:CellularComponent equatorial cell cortex The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression. go-plus.json http://purl.obolibrary.org/obo/GO_1990753 CHEBI:27518 biolink:ChemicalSubstance acetylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27518 chebi_ph7_3 CHEBI:27512 biolink:ChemicalSubstance (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27512 CHEBI:27513 biolink:ChemicalSubstance precorrin-6X go-plus.json http://purl.obolibrary.org/obo/CHEBI_27513 CHEBI:27514 biolink:ChemicalSubstance genistein 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27514 UBERON:0010143 biolink:AnatomicalEntity seminal vesicle fluid A bodily secretion that is produced by a seminal vesicle. go-plus.json vesicular fluid|secretion of seminal vesicle|seminal vesicle secretion|seminal fluid http://purl.obolibrary.org/obo/UBERON_0010143 CHEBI:27510 biolink:ChemicalSubstance umbelliferone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27510 chebi_ph7_3 UBERON:0010141 biolink:AnatomicalEntity primitive sex cord of indifferent gonad A sex cord that is part of a indifferent gonad. go-plus.json indifferent sex cord|primitive sex cords http://purl.obolibrary.org/obo/UBERON_0010141 UBERON:0010147 biolink:AnatomicalEntity male accessory sex gland Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male. go-plus.json male accessory gland|male accessory reproductive gland http://purl.obolibrary.org/obo/UBERON_0010147 UBERON:0010137 biolink:AnatomicalEntity polarized epithelium A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010137 NCBITaxon:50557 biolink:OrganismalEntity Insecta go-plus.json true insects|insects http://purl.obolibrary.org/obo/NCBITaxon_50557 GO:1990758 biolink:BiologicalProcess mitotic sister chromatid biorientation The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression. go-plus.json http://purl.obolibrary.org/obo/GO_1990758 GO:1990759 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990759 GO:1990754 biolink:BiologicalProcess obsolete GABAergic neuronal action potential OBSOLETE. An action potential that occurs in a GABAergic neuron. go-plus.json GABAergic neuronal action potential http://purl.obolibrary.org/obo/GO_1990754 GO:1990755 biolink:BiologicalProcess mitotic spindle microtubule depolymerization The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle. go-plus.json mitotic spindle microtubule depolymerisation http://purl.obolibrary.org/obo/GO_1990755 GO:1990756 biolink:MolecularActivity ubiquitin ligase-substrate adaptor activity The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins. go-plus.json protein binding, bridging involved in substrate recognition for ubiquitination|ubiquitin ligase substrate adaptor http://purl.obolibrary.org/obo/GO_1990756 GO:1990757 biolink:MolecularActivity ubiquitin ligase activator activity Binds to and increases the activity of a ubiquitin ligase. go-plus.json mitotic anaphase-promoting complex activator activity http://purl.obolibrary.org/obo/GO_1990757 GO:1990761 biolink:CellularComponent growth cone lamellipodium A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_1990761 GO:1990762 biolink:BiologicalProcess cytoplasmic alanyl-tRNA aminoacylation The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation. go-plus.json http://purl.obolibrary.org/obo/GO_1990762 GO:1990763 biolink:MolecularActivity arrestin family protein binding Binding to a member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors. go-plus.json http://purl.obolibrary.org/obo/GO_1990763 GO:1990764 biolink:BiologicalProcess myofibroblast contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast. go-plus.json MFB contraction|MF contraction http://purl.obolibrary.org/obo/GO_1990764 CHEBI:27522 biolink:ChemicalSubstance rutinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27522 chebi_ph7_3 GO:1990760 biolink:MolecularActivity osmolarity-sensing cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides. go-plus.json http://purl.obolibrary.org/obo/GO_1990760 UBERON:0009141 biolink:AnatomicalEntity craniocervical region vein A vein that is part of a craniocervical region. go-plus.json vein of head and neck|craniocervical vein|head and neck veins http://purl.obolibrary.org/obo/UBERON_0009141 UBERON:0010131 biolink:AnatomicalEntity conducting tissue of heart Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers. go-plus.json specialized conducting tissue of heart|specialized muscle tissue of heart http://purl.obolibrary.org/obo/UBERON_0010131 UBERON:0010130 biolink:AnatomicalEntity embryonic autopod plate The distal elements of the developing limb of vertebrates that will give rise to the autopod (e.g. manus, pes, paw) go-plus.json autopod plate|limb plate http://purl.obolibrary.org/obo/UBERON_0010130 UBERON:0010135 biolink:AnatomicalEntity sensory circumventricular organ A circumventricular organ that is capable of monitoring the levels of substances to the cerebrospinal fluid. go-plus.json humerosensory system organ|humerosensory circumventricular organ|sensitive circumventricular organs|sensory CVOs|sensory circumventricular organs|humerosensory system|sensitive organs http://purl.obolibrary.org/obo/UBERON_0010135 UBERON:0010136 biolink:AnatomicalEntity epithelial sheet An epithelial sheet is a flat surface consisting of closely packed epithelial cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010136 UBERON:0010133 biolink:AnatomicalEntity neuroendocrine gland any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli go-plus.json neuroendocrine system gland http://purl.obolibrary.org/obo/UBERON_0010133 UBERON:0010134 biolink:AnatomicalEntity secretory circumventricular organ A circumventricular organ that is capable of secreting substances into the cerebrospinal fluid. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010134 UBERON:0010129 biolink:AnatomicalEntity femur cartilage element A femur endochondral element that is composed primarily of cartilage tissue. go-plus.json femoral cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010129 UBERON:0010126 biolink:AnatomicalEntity future nucleus ambiguus A gray matter that has the potential to develop into a nucleus ambiguus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010126 UBERON:0010127 biolink:AnatomicalEntity future dorsal motor nucleus of vagus A gray matter that has the potential to develop into a dorsal motor nucleus of vagus nerve. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010127 GO:1990769 biolink:CellularComponent proximal neuron projection The portion of an axon or dendrite that is close to the neuronal cell body. go-plus.json http://purl.obolibrary.org/obo/GO_1990769 UBERON:0009142 biolink:AnatomicalEntity entire embryonic mesenchyme Sum total of mesenchyme in the embryo. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009142 UBERON:0009145 biolink:AnatomicalEntity pharyngeal region of foregut go-plus.json pharyngeal region http://purl.obolibrary.org/obo/UBERON_0009145 GO:1990765 biolink:BiologicalProcess colon smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum. go-plus.json http://purl.obolibrary.org/obo/GO_1990765 GO:1990766 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990766 GO:1990767 biolink:BiologicalProcess prostaglandin receptor internalization The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_1990767 GO:1990768 biolink:BiologicalProcess gastric mucosal blood circulation The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products. go-plus.json stomach mucosal blood circulation http://purl.obolibrary.org/obo/GO_1990768 UBERON:0009149 biolink:AnatomicalEntity foramen primum opening in the septum primum between the two atria of the embryonic heart[TMD]. go-plus.json primary interatrial foramen|interatrial foramen primum|ostium primum http://purl.obolibrary.org/obo/UBERON_0009149 GO:1990772 biolink:BiologicalProcess substance P secretion The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity. go-plus.json http://purl.obolibrary.org/obo/GO_1990772 GO:1990773 biolink:BiologicalProcess matrix metallopeptidase secretion The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins. go-plus.json MMP secretion|matrix metalloproteinase secretion http://purl.obolibrary.org/obo/GO_1990773 GO:1990774 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990774 GO:1990775 biolink:BiologicalProcess endothelin production The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. go-plus.json endothelin-1 secretion|endothelin secretion|endothelin-2 production|endothelin-3 production|EDN1 production|EDN2 production|EDN3 production http://purl.obolibrary.org/obo/GO_1990775 gocheck_do_not_annotate GO:1990770 biolink:BiologicalProcess small intestine smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine. go-plus.json http://purl.obolibrary.org/obo/GO_1990770 GO:1990771 biolink:BiologicalProcess clathrin-dependent extracellular exosome endocytosis The clathrin-mediated endocytosis of an extracellular exosome. go-plus.json clathrin-mediated extracellular exosome endocytosis|exosome related http://purl.obolibrary.org/obo/GO_1990771 UBERON:0010124 biolink:AnatomicalEntity future inferior salivatory nucleus A gray matter that has the potential to develop into a inferior salivatory nucleus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010124 UBERON:0010125 biolink:AnatomicalEntity future superior salivatory nucleus A gray matter that has the potential to develop into a superior salivatory nucleus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010125 UBERON:0010123 biolink:AnatomicalEntity future facial nucleus A gray matter that has the potential to develop into a facial nucleus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010123 UBERON:0009133 biolink:AnatomicalEntity pleuroperitoneal membrane A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities. go-plus.json pleuroperitoneal membranes|pleuroperitoneal fold http://purl.obolibrary.org/obo/UBERON_0009133 GO:1990776 biolink:BiologicalProcess response to angiotensin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen. go-plus.json http://purl.obolibrary.org/obo/GO_1990776 GO:1990777 biolink:CellularComponent lipoprotein particle A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_1990777 GO:1990778 biolink:BiologicalProcess protein localization to cell periphery A process in which a protein is transported to, or maintained in, the cell periphery. go-plus.json http://purl.obolibrary.org/obo/GO_1990778 GO:1990779 biolink:CellularComponent glycoprotein Ib-IX-V complex A transmembrane signalling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation. go-plus.json GPIb-IX-V complex|GPIb-V-IX complex|CD42 http://purl.obolibrary.org/obo/GO_1990779 GO:1990783 biolink:CellularComponent periphagosomal region of cytoplasm Cytoplasm situated near, or occurring around, a phagosome. go-plus.json http://purl.obolibrary.org/obo/GO_1990783 CHEBI:27504 biolink:ChemicalSubstance mitomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_27504 GO:1990784 biolink:BiologicalProcess response to dsDNA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus. go-plus.json response to double-stranded DNA http://purl.obolibrary.org/obo/GO_1990784 CHEBI:27505 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27505 GO:1990785 biolink:BiologicalProcess response to water-immersion restraint stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile. go-plus.json response to immobilization stress combined with water immersion http://purl.obolibrary.org/obo/GO_1990785 GO:1990786 biolink:BiologicalProcess cellular response to dsDNA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990786 NCBITaxon:183939 biolink:OrganismalEntity Methanococci go-plus.json Methanothermea http://purl.obolibrary.org/obo/NCBITaxon_183939 GO:1990780 biolink:CellularComponent cytoplasmic side of dendritic spine plasma membrane The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine. go-plus.json http://purl.obolibrary.org/obo/GO_1990780 GO:1990781 biolink:BiologicalProcess response to immobilization stress combined with electrical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile. go-plus.json http://purl.obolibrary.org/obo/GO_1990781 CHEBI:27503 biolink:ChemicalSubstance aldehydo-D-mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27503 chebi_ph7_3 GO:1990782 biolink:MolecularActivity protein tyrosine kinase binding Binding to protein tyrosine kinase. go-plus.json tyrosine kinase binding http://purl.obolibrary.org/obo/GO_1990782 UBERON:0009128 biolink:AnatomicalEntity lateral line placode An ectodermal placode that will develop into the components of the lateral line system go-plus.json lateral line placodes http://purl.obolibrary.org/obo/UBERON_0009128 UBERON:0009129 biolink:AnatomicalEntity right atrium endocardium Endocardium that is part of the right atrium. go-plus.json right atrial endocardium|endocardium of right atrium|right atrium endocardial tissue http://purl.obolibrary.org/obo/UBERON_0009129 UBERON:0009122 biolink:AnatomicalEntity adenohypophyseal placode The adenohypophyseal placode forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary go-plus.json pituitary placode http://purl.obolibrary.org/obo/UBERON_0009122 UBERON:0009124 biolink:AnatomicalEntity geniculate placode Rostralmost epibranchial placode. Associated with 1st branchial cleft. go-plus.json hyoid placode|facial placode|hyoid VII placode|facial epibranchial placode|epibranchial placode 1|facial VII placode http://purl.obolibrary.org/obo/UBERON_0009124 GO:1990787 biolink:BiologicalProcess negative regulation of hh target transcription factor activity Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling. go-plus.json negative regulation of hedgehog target transcription factor http://purl.obolibrary.org/obo/GO_1990787 GO:1990788 biolink:CellularComponent GLI-SUFU complex A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990788 UBERON:0009125 biolink:AnatomicalEntity petrosal placode Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft. go-plus.json glossopharyngeal placode|glossopharyngeal epibranchial placode|epibranchial placode 2|glossopharyngeal IX placode http://purl.obolibrary.org/obo/UBERON_0009125 GO:1990789 biolink:BiologicalProcess thyroid gland epithelial cell proliferation The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population. go-plus.json thyroid follicular cell proliferation|Hurthle cell proliferation http://purl.obolibrary.org/obo/GO_1990789 UBERON:0009127 biolink:AnatomicalEntity epibranchial ganglion Cranial ganglion which develops from an epibranchial placode. go-plus.json epibranchial ganglia http://purl.obolibrary.org/obo/UBERON_0009127 NCBITaxon:183968 biolink:OrganismalEntity Thermococci go-plus.json Protoarchaea http://purl.obolibrary.org/obo/NCBITaxon_183968 UBERON:0009191 biolink:AnatomicalEntity sphenoid bone pre-cartilage condensation A sphenoid endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009191 UBERON:0009193 biolink:AnatomicalEntity sphenoid cartilage element A sphenoid endochondral element that is composed primarily of cartilage tissue. go-plus.json sphenoid bone cartilage condensation http://purl.obolibrary.org/obo/UBERON_0009193 UBERON:0010183 biolink:AnatomicalEntity liver trabecula A trabecula that is part of a liver go-plus.json hepatic trabecula http://purl.obolibrary.org/obo/UBERON_0010183 UBERON:0009196 biolink:AnatomicalEntity indifferent external genitalia go-plus.json http://purl.obolibrary.org/obo/UBERON_0009196 UBERON:0010186 biolink:AnatomicalEntity male urethral gland any of the numerous small mucous-secreting glands located in the wall of the penile urethra go-plus.json urethral gland (male)|gland of male urethra|Littre's gland|gland of Littre|male urethra gland|glandulae urethrales urethrae masculinae http://purl.obolibrary.org/obo/UBERON_0010186 UBERON:0010187 biolink:AnatomicalEntity female urethral gland An urethral gland that is part of a female urethra. go-plus.json urethral gland (female)|gland of female urethra|female urethra gland http://purl.obolibrary.org/obo/UBERON_0010187 UBERON:0010188 biolink:AnatomicalEntity protuberance A roughly circular bulge in a surface. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010188 UBERON:0010189 biolink:AnatomicalEntity right atrium venous valve go-plus.json right venous valve http://purl.obolibrary.org/obo/UBERON_0010189 PO:0009020 biolink:OntologyClass meristem L1 layer A portion of meristem tissue (PO:0009013) that is the outermost layer of a shoot apical meristem (PO:0020148) and gives rise to a shoot system epidermis (PO:0006035). go-plus.json 分裂組織 L1 (Japanese, exact)|meristema L1 (Spanish, exact)|tunica (related) http://purl.obolibrary.org/obo/PO_0009020 OPL:0000114 biolink:OntologyClass amastigote stage A parasite lifecycle stage is a nonflagellate intracellular developmental stage in the trypanosomatid parasites lifecycle that occurs in mammalian host. go-plus.json http://purl.obolibrary.org/obo/OPL_0000114 CHEBI:600520 biolink:ChemicalSubstance micafungin go-plus.json http://purl.obolibrary.org/obo/CHEBI_600520 GO:1990718 biolink:CellularComponent axonemal central pair projection Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_1990718 GO:1990719 biolink:CellularComponent C1 axonemal microtubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections. go-plus.json C1 tubule http://purl.obolibrary.org/obo/GO_1990719 PO:0009027 biolink:OntologyClass megasporophyll A structure upon which (or in the axil of which) one or more megasporangia are borne; in flowering plants, a carpel. go-plus.json megasporofilo (Spanish, exact)|大胞子葉 (Japanese, exact)|macrosporophyll (related)|cone scale (narrow)|ovuliferous scale (narrow) http://purl.obolibrary.org/obo/PO_0009027 GO:1990714 biolink:MolecularActivity hydroxyproline O-galactosyltransferase activity Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone. go-plus.json HPGT http://purl.obolibrary.org/obo/GO_1990714 UBERON:0009198 biolink:AnatomicalEntity craniofacial suture Any suture between cranial and/or facial bones. go-plus.json joint of the skull bones|articulation of skull bones http://purl.obolibrary.org/obo/UBERON_0009198 PO:0009028 biolink:OntologyClass microsporophyll A structure on which one or more microsporangia are borne; in flowering plants, the stamen. go-plus.json microsporofilo (Spanish, exact)|小胞子葉 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009028 GO:1990715 biolink:MolecularActivity mRNA CDS binding Binding to an mRNA molecule coding sequence (CDS). go-plus.json mRNA coding sequence binding|mRNA coding region binding http://purl.obolibrary.org/obo/GO_1990715 UBERON:0009199 biolink:AnatomicalEntity facial suture Any suture between facial bones. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009199 GO:1990716 biolink:CellularComponent axonemal central apparatus Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_1990716 PO:0009029 biolink:OntologyClass stamen A microsporophyll bearing one or more microsporangia. go-plus.json Zea stamen (narrow)|estambre (Spanish, exact)|Poaceae stamen (narrow)|雄蕊 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009029 NCBITaxon:183963 biolink:OrganismalEntity Halobacteria go-plus.json Halomebacteria http://purl.obolibrary.org/obo/NCBITaxon_183963 GO:1990717 biolink:CellularComponent axonemal central bridge Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_1990717 GO:1990710 biolink:CellularComponent MutS complex A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations. go-plus.json MutS mismatch repair complex http://purl.obolibrary.org/obo/GO_1990710 GO:1990711 biolink:CellularComponent beta-catenin-ICAT complex Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex. go-plus.json CTNNB1-CTNNBIP1 complex|Beta-catenin-ICAT complex http://purl.obolibrary.org/obo/GO_1990711 PO:0009025 biolink:OntologyClass vascular leaf A leaf (PO:0025034) in a vascular plant. go-plus.json foliage leaf (exact)|ascidium (narrow)|macrophyll (related)|vascular leaves (exact, plural)|pitcher-blade (narrow)|frond (narrow)|trophophyll (narrow)|megaphyll (related)|fiddlehead (narrow)|scale-like leaf (narrow)|leaf, vascular (exact)|ascidia (narrow)|pitcher blade (narrow)|hoja vascular (Spanish, exact)|needle-like leaf (narrow)|sterile frond (narrow)|pitcher (narrow)|crozier (related)|維管束のある葉, または維管束植物の葉 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009025 GO:1990712 biolink:CellularComponent HFE-transferrin receptor complex A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription. go-plus.json http://purl.obolibrary.org/obo/GO_1990712 GO:1990713 biolink:CellularComponent survivin complex A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC). go-plus.json survivin homodimer complex|Baculoviral IAP repeat-containing protein 5 complex http://purl.obolibrary.org/obo/GO_1990713 PO:0009026 biolink:OntologyClass sporophyll A leaf-like organ on which one or more sporangia are borne. go-plus.json 胞子葉 (Japanese, exact)|spore leaf (exact)|esporofilo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009026 GO:1990720 biolink:CellularComponent C2 axonemal microtubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections. go-plus.json C2 tubule http://purl.obolibrary.org/obo/GO_1990720 UBERON:0010171 biolink:AnatomicalEntity strand of hair of face A strand of hair that is part of a face. go-plus.json facial hair|hair of face|face hair|face hair strand http://purl.obolibrary.org/obo/UBERON_0010171 PO:0009009 biolink:OntologyClass plant embryo A whole plant (PO:0000003) that participates in the plant embryo stage (PO:0007631). go-plus.json germ (related)|植物胚 (Japanese, exact)|embryo (broad)|embrión (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009009 UBERON:0010172 biolink:AnatomicalEntity bulb of aorta The portion of the left ventricular outflow tract delineated by the sinotubular ridge superiorly and the bases of the valve leaflets inferiorly; it comprises the aortic sinuses, the aortic valve leaflets, the commissures, and the interleaflet triangles go-plus.json supraaortic valve area|bulbus aortae|root of aorta|aortic bulb|aorta bulb|aortic root|bulb of ascending aorta http://purl.obolibrary.org/obo/UBERON_0010172 PO:0009010 biolink:OntologyClass seed A multi-tissue plant structure (PO:0025496) that develops from a plant ovule (PO:0020003) and has as parts a plant embryo (PO:0009009) enclosed in a seed coat (PO:0009088). go-plus.json 種子 (Japanese, exact)|pyrene (narrow)|semilla (Spanish, exact)|diaspore (broad) http://purl.obolibrary.org/obo/PO_0009010 PO:0009011 biolink:OntologyClass plant structure A plant anatomical entity (PO:0025131) that is, or was, part of a plant, or was derived from a part of a plant. go-plus.json 植物 構造 (Japanese, exact)|estructura vegetal (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009011 GO:1990729 biolink:BiologicalProcess primary miRNA modification The covalent alteration of one or more nucleotides within a primary miRNA molecule to produce a primary miRNA molecule with a sequence that differs from that coded genetically. go-plus.json http://purl.obolibrary.org/obo/GO_1990729 GO:1990725 biolink:MolecularActivity cord factor receptor activity Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity. Wikipedia:Cord_factor go-plus.json trehalose 6,6'-dimycolate receptor activity|TMD receptor activity http://purl.obolibrary.org/obo/GO_1990725 GO:1990726 biolink:CellularComponent Lsm1-7-Pat1 complex A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1990726 GO:1990727 biolink:CellularComponent tubulin folding cofactor complex A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur. go-plus.json http://purl.obolibrary.org/obo/GO_1990727 GO:1990728 biolink:CellularComponent mitotic spindle assembly checkpoint MAD1-MAD2 complex A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex. go-plus.json MAD1-MAD2 complex http://purl.obolibrary.org/obo/GO_1990728 GO:1990721 biolink:CellularComponent obsolete prostatic acid phosphatase complex OBSOLETE. A protein complex that is capable of dephosphorylation of alky, aryl and acyl orthophosphate monoesters and phosphorylated proteins. Optimal activity in acidic environment (pH 4-6). In mammals it consists of a homodimer of ACPP. go-plus.json PAP complex|ACPP homodimer complex|prostatic acid phosphatase complex http://purl.obolibrary.org/obo/GO_1990721 PO:0009012 biolink:OntologyClass plant structure development stage A stage in the life of a plant structure (PO:0009011) during which the plant structure undergoes developmental processes. go-plus.json plant growth and development stage (exact)|etapa de desarrollo de estructura vegetal (Spanish, exact)|Arabidopsis growth (related) http://purl.obolibrary.org/obo/PO_0009012 PO:0009013 biolink:OntologyClass portion of meristem tissue A portion of plant tissue (PO:0009007) in which plant cells (PO:0009002) have retained their embryonic characteristics, or have reverted to them secondarily, and that divide to produce new cells that can undergo differentiation to form mature tissues, i.e. they have a capacity for morphogenesis and growth. go-plus.json 分裂組織 (Japanese, exact)|meristema (Spanish, exact)|meristematic tissue (exact)|meristem (exact) http://purl.obolibrary.org/obo/PO_0009013 GO:1990722 biolink:CellularComponent DAPK1-calmodulin complex A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding. go-plus.json death-associated protein kinase 1 - calmodulin complex http://purl.obolibrary.org/obo/GO_1990722 GO:1990723 biolink:CellularComponent cytoplasmic periphery of the nuclear pore complex Cytoplasm situated in close proximity to a nuclear pore complex. go-plus.json associated with the nuclear pore http://purl.obolibrary.org/obo/GO_1990723 GO:1990724 biolink:CellularComponent galectin complex A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes. go-plus.json galectin-2 complex|galectin-1 complex http://purl.obolibrary.org/obo/GO_1990724 PO:0009015 biolink:OntologyClass portion of vascular tissue A portion of plant tissue (PO:0009007) that has as part one or more tracheary elements (PO:0000290) or sieve elements (PO:0025406). go-plus.json 維管束細胞の一部 (Japanese, exact)|vascular tissue (exact)|porción de tejido vascular (Spanish, exact)|vascular system (related) http://purl.obolibrary.org/obo/PO_0009015 CHEBI:76504 biolink:ChemicalSubstance (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76504 chebi_ph7_3 CHEBI:76505 biolink:ChemicalSubstance (3R,16Z,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76505 chebi_ph7_3 GO:1990730 biolink:CellularComponent VCP-NSFL1C complex A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97. go-plus.json p97-p47 complex http://purl.obolibrary.org/obo/GO_1990730 CHEBI:76502 biolink:ChemicalSubstance (3R,14Z,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76502 chebi_ph7_3 GO:1990731 biolink:BiologicalProcess UV-damage excision repair, DNA incision A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). go-plus.json alternative excision repair, DNA incision|nucleic acid cleavage involved in UV-damage excision repair|UVDE-dependent excision repair, DNA incision|DNA incision involved in UVDE-dependent excision repair|DNA incision involved in UV-damaged DNA endonuclease-dependent excision repair|DNA incision involved in UVER|DNA incision involved in AER|DNA incision involved in alternative excision repair|DNA incision involved in UV-damage excision repair|UV-damaged DNA endonuclease-dependent excision repair, DNA incision http://purl.obolibrary.org/obo/GO_1990731 CHEBI:76503 biolink:ChemicalSubstance monobutyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_76503 chebi_ph7_3 UBERON:0010160 biolink:AnatomicalEntity lumen of lymphatic vessel An anatomical cavity that surrounded_by a lymphatic vessel. go-plus.json lymphatic vessel lumen|lumen of lymphatic duct http://purl.obolibrary.org/obo/UBERON_0010160 CHEBI:76508 biolink:ChemicalSubstance (3R,11Z)-3-hydroxyicosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76508 UBERON:0010161 biolink:AnatomicalEntity lumen of blood vessel An anatomical cavity that surrounded_by a blood vessel. go-plus.json blood vessel lumen http://purl.obolibrary.org/obo/UBERON_0010161 CHEBI:76509 biolink:ChemicalSubstance (2E,11Z)-icosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76509 CHEBI:76506 biolink:ChemicalSubstance (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76506 chebi_ph7_3 CHEBI:76507 biolink:ChemicalSubstance marine metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76507 UBERON:0010164 biolink:AnatomicalEntity collection of hairs An anatomical cluster that composed_primarily_of a strand of hair. go-plus.json set of hairs|pili|hairs set|hairs http://purl.obolibrary.org/obo/UBERON_0010164 UBERON:0010165 biolink:AnatomicalEntity collection of hair on face A collection of hairs that is part of a face. go-plus.json set of facial hairs|facial hairs set|facial hair http://purl.obolibrary.org/obo/UBERON_0010165 UBERON:0010162 biolink:AnatomicalEntity post-anal tail tip The distal end of the tail go-plus.json end of tail|tail tip http://purl.obolibrary.org/obo/UBERON_0010162 GO:1990736 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell membrane depolarization Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell. go-plus.json regulation of vascular smooth muscle cell membrane depolarization http://purl.obolibrary.org/obo/GO_1990736 PO:0009005 biolink:OntologyClass root A plant axis (PO:0025004) that lacks shoot axis nodes (PO:0005004) and usually grows indeterminately. go-plus.json raíz (Spanish, exact)|radices (exact, plural)|radix (exact)|climbing root (narrow)|根 (Japanese, exact)|aerial root (narrow) http://purl.obolibrary.org/obo/PO_0009005 GO:1990737 biolink:BiologicalProcess response to manganese-induced endoplasmic reticulum stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus. go-plus.json response to Mn-induced ER stress|manganese-induced ER stress response|response to manganese-induced ER stress http://purl.obolibrary.org/obo/GO_1990737 PO:0009006 biolink:OntologyClass shoot system A collective plant organ structure (PO:0025007) that produces shoot-borne portions of meristem tissue (PO:0009013) and the plant structures (PO:0009011) that arise from them. go-plus.json tree crown (narrow)|thallus (related)|シュート系、苗条系 (Japanese, exact)|sistema de epiblasto (epiblastema) (Spanish, exact)|shoot (related)|Poaceae crown (related)|thalli (related) http://purl.obolibrary.org/obo/PO_0009006 PO:0009007 biolink:OntologyClass portion of plant tissue A plant structure (PO:0009011) that consists predominantly of similarly specialized plant cells (PO:0009002) of one or more types. go-plus.json plant tissue (related)|portion of tissue (broad)|tissue (broad)|porción de un tejido vegetal (Spanish, exact)|植物組織の一部 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009007 GO:1990738 biolink:MolecularActivity pseudouridine 5'-phosphatase activity Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate. RHEA:10944|EC:3.1.3.96 go-plus.json http://purl.obolibrary.org/obo/GO_1990738 PO:0009008 biolink:OntologyClass plant organ A multi-tissue plant structure (PO:0025496) that is a functional unit, is a proper part of a whole plant (PO:0000003), and includes portions of plant tissue (PO:0009007) of at least two different types that derive from a common developmental path. go-plus.json organ (broad)|simple plant organ (related)|植物 器官 (Japanese, exact)|compound plant organ (related)|órgano vegetal (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009008 GO:1990739 biolink:BiologicalProcess granulosa cell proliferation The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. go-plus.json http://purl.obolibrary.org/obo/GO_1990739 GO:1990732 biolink:CellularComponent pyrenoid A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation. Wikipedia:Pyrenoid go-plus.json http://purl.obolibrary.org/obo/GO_1990732 PO:0009001 biolink:OntologyClass fruit A multi-tissue plant structure (PO:0025496) that develops from a gynoecium (PO:0009062), or a single carpel (PO:0009030), and at maturity may have as parts one or more seeds (PO:0009010). go-plus.json dehiscent fruit (broad)|coenocarp (narrow)|aggregate fruit (broad)|果実 (exact, Japanese)|syncarp (narrow)|compound fruit (broad)|multiple fruit (broad)|propagule (broad)|frucht (exact, German)|fruto (exact, Spanish)|indehiscent fruit (broad)|diaspore (broad) http://purl.obolibrary.org/obo/PO_0009001 CHEBI:76500 biolink:ChemicalSubstance triacontanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76500 GO:1990733 biolink:CellularComponent titin-telethonin complex A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils. go-plus.json Titin-Tcap complex http://purl.obolibrary.org/obo/GO_1990733 PO:0009002 biolink:OntologyClass plant cell A cell which is a plant structure (PO:0009011). go-plus.json célula vegetal (Spanish, exact)|cell (broad)|植物細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009002 GO:1990734 biolink:BiologicalProcess astral microtubule anchoring at mitotic spindle pole body Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end. go-plus.json http://purl.obolibrary.org/obo/GO_1990734 GO:1990735 biolink:BiologicalProcess gamma-tubulin complex localization to mitotic spindle pole body Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body. go-plus.json gamma-tubulin complex localisation to mitotic spindle pole body|establishment and maintenance of gamma-tubulin complex localization to mitotic spindle pole body|gamma-tubulin complex localization to mitotic SPB http://purl.obolibrary.org/obo/GO_1990735 CHEBI:76515 biolink:ChemicalSubstance (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76515 chebi_ph7_3 GO:1990740 biolink:MolecularActivity obsolete non-selective anion channel activity OBSOLETE. Enables the non-selective, energy-independent passage of anions across a lipid bilayer down a concentration gradient. go-plus.json nonselective anion channel activity http://purl.obolibrary.org/obo/GO_1990740 GO:1990741 biolink:MolecularActivity obsolete non-selective cation channel activity OBSOLETE. Enables the non-selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient. go-plus.json nonselective cation channel activity http://purl.obolibrary.org/obo/GO_1990741 CHEBI:76513 biolink:ChemicalSubstance (3R,18Z,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76513 chebi_ph7_3 CHEBI:76514 biolink:ChemicalSubstance (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76514 chebi_ph7_3 GO:1990742 biolink:CellularComponent microvesicle An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm. go-plus.json shedding vesicle|extracellular microvesicle|ectosome http://purl.obolibrary.org/obo/GO_1990742 UBERON:0010152 biolink:AnatomicalEntity skin mucus A mucous secretion that is produced by glands in the epidermis. go-plus.json epidermal mucus|skin mucous http://purl.obolibrary.org/obo/UBERON_0010152 UBERON:0010157 biolink:AnatomicalEntity sphenoparietal suture The Sphenoparietal suture is the cranial suture between the sphenoid bone and the parietal bone. go-plus.json sphenoparietal suture of skull|sutura sphenoparietalis|spheno-parietal suture http://purl.obolibrary.org/obo/UBERON_0010157 UBERON:0010156 biolink:AnatomicalEntity sphenofrontal suture The Sphenofrontal suture is the cranial suture between the sphenoid bone and the frontal bone. go-plus.json frontosphenoid suture|sphenofrontal suture of skull|sphenofrontal|sutura sphenofrontalis|spheno-frontal suture http://purl.obolibrary.org/obo/UBERON_0010156 GO:1990747 biolink:BiologicalProcess pancreatic trypsinogen secretion The regulated release of trypsinogen from the cells of the exocrine pancreas. go-plus.json pancreatic trypsinogen release http://purl.obolibrary.org/obo/GO_1990747 GO:1990748 biolink:BiologicalProcess cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. go-plus.json http://purl.obolibrary.org/obo/GO_1990748 GO:1990749 biolink:MolecularActivity polynucleotide adenylyltransferase activator activity Increases the activity of the enzyme polynucleotide adenylyltransferase. go-plus.json http://purl.obolibrary.org/obo/GO_1990749 GO:1990743 biolink:BiologicalProcess protein sialylation A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_1990743 CHEBI:76511 biolink:ChemicalSubstance (3R,13Z)-3-hydroxydocosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76511 GO:1990744 biolink:BiologicalProcess primary miRNA methylation The posttranscriptional addition of methyl groups to specific residues in an primary miRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990744 GO:1990745 biolink:CellularComponent EARP complex A quatrefoil tethering complex required for endocytic recycling. go-plus.json http://purl.obolibrary.org/obo/GO_1990745 GO:1990746 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990746 GO:0098565 biolink:CellularComponent lumenal side of endosome membrane The side (leaflet) of the endosome membrane that faces the lumen. go-plus.json internal leaflet of endosome membrane|internal side of endosome membrane http://purl.obolibrary.org/obo/GO_0098565 GO:0001653 biolink:MolecularActivity peptide receptor activity Combining with an extracellular or intracellular peptide to initiate a change in cell activity. go-plus.json exogenous peptide receptor activity|endogenous peptide receptor activity http://purl.obolibrary.org/obo/GO_0001653 GO:0001654 biolink:BiologicalProcess eye development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. Wikipedia:Eye_development go-plus.json http://purl.obolibrary.org/obo/GO_0001654 GO:0098566 biolink:CellularComponent transport vesicle lumen The volume enclosed within the membrane of a transport vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0098566 GO:0001655 biolink:BiologicalProcess urogenital system development The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0001655 GO:0098563 biolink:CellularComponent intrinsic component of synaptic vesicle membrane The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098563 goslim_synapse GO:0001656 biolink:BiologicalProcess metanephros development The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0001656 GO:0098564 biolink:CellularComponent trans-Golgi network transport vesicle lumen The volume enclosed within the membrane of a trans-Golgi network transport vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0098564 GO:0098561 biolink:CellularComponent methyl accepting chemotaxis protein complex A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0098561 GO:0001650 biolink:CellularComponent fibrillar center A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures. go-plus.json fibrillar centre http://purl.obolibrary.org/obo/GO_0001650 GO:0098562 biolink:CellularComponent cytoplasmic side of membrane The side of a membrane that faces the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0098562 CHEBI:52557 biolink:ChemicalSubstance tetracyclic diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52557 GO:0001651 biolink:CellularComponent dense fibrillar component A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins. NIF_Subcellular:sao1841764412 go-plus.json pars fibrosa http://purl.obolibrary.org/obo/GO_0001651 GO:0001652 biolink:CellularComponent granular component A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm. NIF_Subcellular:sao1217793903 go-plus.json pars granulosa http://purl.obolibrary.org/obo/GO_0001652 GO:0098560 biolink:CellularComponent cytoplasmic side of late endosome membrane The side (leaflet) of the late endosome membrane that faces the cytoplasm. go-plus.json external leaflet of late endosome membrane|external side of late endosome membrane http://purl.obolibrary.org/obo/GO_0098560 CHEBI:27595 biolink:ChemicalSubstance 11-epi-prostaglandin F2alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_27595 GO:1902137 biolink:BiologicalProcess (-)-secoisolariciresinol catabolic process The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol. go-plus.json (-)-secoisolariciresinol breakdown|(-)-secoisolariciresinol catabolism|(-)-secoisolariciresinol degradation http://purl.obolibrary.org/obo/GO_1902137 GO:1902138 biolink:BiologicalProcess (-)-secoisolariciresinol biosynthetic process The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol. go-plus.json (-)-secoisolariciresinol anabolism|(-)-secoisolariciresinol synthesis|(-)-secoisolariciresinol formation|(-)-secoisolariciresinol biosynthesis http://purl.obolibrary.org/obo/GO_1902138 GO:1902135 biolink:BiologicalProcess (+)-secoisolariciresinol biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol. go-plus.json (+)-secoisolariciresinol anabolism|(+)-secoisolariciresinol synthesis|(+)-secoisolariciresinol formation|(+)-secoisolariciresinol biosynthesis http://purl.obolibrary.org/obo/GO_1902135 CHEBI:27592 biolink:ChemicalSubstance ectoine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27592 GO:1902136 biolink:BiologicalProcess (-)-secoisolariciresinol metabolic process The chemical reactions and pathways involving (-)-secoisolariciresinol. go-plus.json (-)-secoisolariciresinol metabolism http://purl.obolibrary.org/obo/GO_1902136 GO:1902133 biolink:BiologicalProcess (+)-secoisolariciresinol metabolic process The chemical reactions and pathways involving (+)-secoisolariciresinol. go-plus.json (+)-secoisolariciresinol metabolism http://purl.obolibrary.org/obo/GO_1902133 GO:1902134 biolink:BiologicalProcess (+)-secoisolariciresinol catabolic process The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol. go-plus.json (+)-secoisolariciresinol breakdown|(+)-secoisolariciresinol catabolism|(+)-secoisolariciresinol degradation http://purl.obolibrary.org/obo/GO_1902134 CHEBI:27594 biolink:ChemicalSubstance carbon atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27594 chebi_ph7_3 GO:1902140 biolink:BiologicalProcess response to inositol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902140 GO:1902141 biolink:BiologicalProcess cellular response to inositol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902141 GO:0001657 biolink:BiologicalProcess ureteric bud development The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0001657 GO:0098569 biolink:CellularComponent internal side of mycolate outer membrane The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. go-plus.json http://purl.obolibrary.org/obo/GO_0098569 GO:0001658 biolink:BiologicalProcess branching involved in ureteric bud morphogenesis The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. go-plus.json ureteric bud branching http://purl.obolibrary.org/obo/GO_0001658 GO:0098567 biolink:CellularComponent periplasmic side of plasma membrane The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098567 GO:0001659 biolink:BiologicalProcess temperature homeostasis A homeostatic process in which an organism modulates its internal body temperature. Wikipedia:Thermoregulation go-plus.json thermoregulation http://purl.obolibrary.org/obo/GO_0001659 GO:0098568 biolink:CellularComponent external side of mycolate outer membrane The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098568 GO:0001664 biolink:MolecularActivity G protein-coupled receptor binding Binding to a G protein-coupled receptor. Reactome:R-HSA-500717 go-plus.json G protein coupled receptor binding|G-protein coupled receptor binding|G-protein-coupled receptor ligand|G protein coupled receptor ligand http://purl.obolibrary.org/obo/GO_0001664 GO:0098576 biolink:CellularComponent lumenal side of membrane Any side (leaflet) of a membrane that faces the lumen of an organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0098576 GO:0001665 biolink:MolecularActivity alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein. EC:2.4.99.3|Reactome:R-HSA-4084980|RHEA:11136|MetaCyc:2.4.99.3-RXN|Reactome:R-HSA-9603991 go-plus.json GalNAc alpha-2,6-sialyltransferase I activity|CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity http://purl.obolibrary.org/obo/GO_0001665 GO:0098577 biolink:CellularComponent inactive sex chromosome A sex chromosome that has been inactivated. go-plus.json inactivated sex chromosome http://purl.obolibrary.org/obo/GO_0098577 GO:0001666 biolink:BiologicalProcess response to hypoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. go-plus.json response to intermittent hypoxia|response to lowered oxygen tension|response to hypoxic stress|response to sustained hypoxia http://purl.obolibrary.org/obo/GO_0001666 GO:0098574 biolink:CellularComponent cytoplasmic side of lysosomal membrane The side (leaflet) of the lysosomal membrane that faces the cytoplasm. go-plus.json external leaflet of lysosomal membrane|external side of lysosomal membrane http://purl.obolibrary.org/obo/GO_0098574 GO:0001667 biolink:BiologicalProcess ameboidal-type cell migration Cell migration that is accomplished by extension and retraction of a pseudopodium. go-plus.json amoeboidal cell migration|ameboid cell migration|amoeboid cell migration http://purl.obolibrary.org/obo/GO_0001667 GO:0098575 biolink:CellularComponent lumenal side of lysosomal membrane The side (leaflet) of the lysosomal membrane that faces the lumen. go-plus.json internal side of lysosomal membrane|internal leaflet of lysosomal membrane http://purl.obolibrary.org/obo/GO_0098575 GO:0098572 biolink:CellularComponent stromal side of plastid thylakoid membrane The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098572 GO:0001660 biolink:BiologicalProcess fever generation The heat generation process that results in a rise in body temperature above the normal, often as a response to infection. Wikipedia:Fever go-plus.json pyrexia http://purl.obolibrary.org/obo/GO_0001660 GO:0098573 biolink:CellularComponent intrinsic component of mitochondrial membrane The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to mitochondrial membrane http://purl.obolibrary.org/obo/GO_0098573 GO:0001661 biolink:BiologicalProcess conditioned taste aversion A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus. Wikipedia:Conditioned_taste_aversion|Wikipedia:Taste_aversion go-plus.json http://purl.obolibrary.org/obo/GO_0001661 GO:0001662 biolink:BiologicalProcess behavioral fear response An acute behavioral change resulting from a perceived external threat. go-plus.json behavioural fear response http://purl.obolibrary.org/obo/GO_0001662 GO:0098570 biolink:CellularComponent stromal side of plastid inner membrane The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098570 GO:0001663 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001663 GO:0098571 biolink:CellularComponent lumenal side of plastid thylakoid membrane The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098571 GO:1902148 biolink:BiologicalProcess positive regulation of response to cytokinesis checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling. go-plus.json upregulation of cytokinesis checkpoint effector process|up-regulation of response to signal involved in cytokinesis checkpoint|upregulation of response to cytokinesis checkpoint signaling|up regulation of cytokinesis checkpoint effector process|positive regulation of cytokinesis checkpoint effector process|upregulation of response to signal involved in cytokinesis checkpoint|activation of response to cytokinesis checkpoint signaling|up-regulation of response to cytokinesis checkpoint signaling|activation of cytokinesis checkpoint effector process|up-regulation of cytokinesis checkpoint effector process|up regulation of response to signal involved in cytokinesis checkpoint|positive regulation of response to signal involved in cytokinesis checkpoint|up regulation of response to cytokinesis checkpoint signaling|activation of response to signal involved in cytokinesis checkpoint http://purl.obolibrary.org/obo/GO_1902148 GO:1902149 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902149 GO:1902146 biolink:BiologicalProcess positive regulation of response to cell cycle checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling. go-plus.json upregulation of response to signal involved in G1/S transition checkpoint|activation of cell cycle checkpoint effector process|up-regulation of response to G1/S transition checkpoint signaling|activation of G1/S transition checkpoint effector process|upregulation of response to signal involved in G2/M transition checkpoint|up-regulation of G2/M transition checkpoint effector process|positive regulation of cell cycle checkpoint effector process|up-regulation of response to G2/M transition checkpoint signaling|up regulation of response to cell cycle checkpoint signaling|activation of response to G1/S transition checkpoint signaling|up regulation of cell cycle checkpoint effector process|activation of response to cell cycle checkpoint signaling|upregulation of response to signal involved in cell cycle checkpoint|up regulation of response to signal involved in G1/S transition checkpoint|up-regulation of G1/S transition checkpoint effector process|activation of response to G2/M transition checkpoint signaling|positive regulation of response to signal involved in G1/S transition checkpoint|positive regulation of response to G1/S transition checkpoint signaling|upregulation of G2/M transition checkpoint effector process|up regulation of response to G1/S transition checkpoint signaling|up regulation of response to signal involved in G2/M transition checkpoint|positive regulation of response to signal involved in G2/M transition checkpoint|activation of response to signal involved in G1/S transition checkpoint|positive regulation of response to G2/M transition checkpoint signaling|upregulation of cell cycle checkpoint effector process|up-regulation of response to signal involved in cell cycle checkpoint|upregulation of G1/S transition checkpoint effector process|up regulation of response to G2/M transition checkpoint signaling|up-regulation of response to cell cycle checkpoint signaling|activation of response to signal involved in G2/M transition checkpoint|up-regulation of response to signal involved in G1/S transition checkpoint|upregulation of response to G1/S transition checkpoint signaling|up regulation of G2/M transition checkpoint effector process|activation of response to signal involved in cell cycle checkpoint|positive regulation of G2/M transition checkpoint effector process|up-regulation of cell cycle checkpoint effector process|up-regulation of response to signal involved in G2/M transition checkpoint|positive regulation of response to signal involved in cell cycle checkpoint|up regulation of G1/S transition checkpoint effector process|upregulation of response to cell cycle checkpoint signaling|upregulation of response to G2/M transition checkpoint signaling|activation of G2/M transition checkpoint effector process|up regulation of response to signal involved in cell cycle checkpoint|positive regulation of G1/S transition checkpoint effector process http://purl.obolibrary.org/obo/GO_1902146 GO:1902147 biolink:BiologicalProcess regulation of response to cytokinesis checkpoint signaling Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling. go-plus.json regulation of cytokinesis checkpoint effector process|regulation of response to signal involved in cytokinesis checkpoint http://purl.obolibrary.org/obo/GO_1902147 GO:1902145 biolink:BiologicalProcess regulation of response to cell cycle checkpoint signaling Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling. go-plus.json regulation of response to signal involved in cell cycle checkpoint|regulation of response to signal involved in G1/S transition checkpoint|regulation of response to signal involved in G2/M transition checkpoint|regulation of cell cycle checkpoint effector process|regulation of response to G1/S transition checkpoint signaling|regulation of G2/M transition checkpoint effector process|regulation of G1/S transition checkpoint effector process|regulation of response to G2/M transition checkpoint signaling http://purl.obolibrary.org/obo/GO_1902145 GO:1902153 biolink:BiologicalProcess regulation of response to DNA damage checkpoint signaling Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling. go-plus.json regulation of response to signal involved in DNA damage checkpoint|regulation of DNA damage checkpoint effector process http://purl.obolibrary.org/obo/GO_1902153 GO:1902154 biolink:BiologicalProcess positive regulation of response to DNA damage checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling. go-plus.json positive regulation of DNA damage checkpoint effector process|up regulation of response to DNA damage checkpoint signaling|activation of response to DNA damage checkpoint signaling|up regulation of DNA damage checkpoint effector process|upregulation of response to signal involved in DNA damage checkpoint|up-regulation of response to signal involved in DNA damage checkpoint|upregulation of DNA damage checkpoint effector process|up-regulation of response to DNA damage checkpoint signaling|activation of response to signal involved in DNA damage checkpoint|up-regulation of DNA damage checkpoint effector process|upregulation of response to DNA damage checkpoint signaling|positive regulation of response to signal involved in DNA damage checkpoint|up regulation of response to signal involved in DNA damage checkpoint|activation of DNA damage checkpoint effector process http://purl.obolibrary.org/obo/GO_1902154 GO:1902151 biolink:BiologicalProcess regulation of response to DNA integrity checkpoint signaling Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling. go-plus.json regulation of DNA integrity checkpoint effector process|regulation of response to signal involved in DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_1902151 GO:1902152 biolink:BiologicalProcess positive regulation of response to DNA integrity checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling. go-plus.json upregulation of response to signal involved in DNA integrity checkpoint|up-regulation of response to DNA integrity checkpoint signaling|activation of response to DNA integrity checkpoint signaling|up regulation of DNA integrity checkpoint effector process|positive regulation of DNA integrity checkpoint effector process|up regulation of response to signal involved in DNA integrity checkpoint|activation of DNA integrity checkpoint effector process|positive regulation of response to signal involved in DNA integrity checkpoint|up regulation of response to DNA integrity checkpoint signaling|up-regulation of DNA integrity checkpoint effector process|activation of response to signal involved in DNA integrity checkpoint|up-regulation of response to signal involved in DNA integrity checkpoint|upregulation of response to DNA integrity checkpoint signaling|upregulation of DNA integrity checkpoint effector process http://purl.obolibrary.org/obo/GO_1902152 GO:1902150 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902150 GO:0001668 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001668 GO:0001669 biolink:CellularComponent acrosomal vesicle A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome. Wikipedia:Acrosome go-plus.json acrosomal granule|acrosome http://purl.obolibrary.org/obo/GO_0001669 GO:0098578 biolink:CellularComponent condensed chromatin of inactivated sex chromosome A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation. go-plus.json http://purl.obolibrary.org/obo/GO_0098578 GO:0098579 biolink:CellularComponent active sex chromosome A sex chromosome that has not been inactivated. go-plus.json http://purl.obolibrary.org/obo/GO_0098579 GO:0098543 biolink:BiologicalProcess detection of other organism The series of events in which a stimulus from another organism is received and converted into a molecular signal. go-plus.json recognition of other organism involved in symbiotic interaction|recognition of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0098543 GO:0001631 biolink:MolecularActivity cysteinyl leukotriene receptor activity Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine. go-plus.json CysLT receptor http://purl.obolibrary.org/obo/GO_0001631 GO:0001632 biolink:MolecularActivity leukotriene B4 receptor activity Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate. go-plus.json BLT receptor http://purl.obolibrary.org/obo/GO_0001632 GO:0098544 biolink:BiologicalProcess maintenance of protein complex location Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away. go-plus.json http://purl.obolibrary.org/obo/GO_0098544 GO:0098541 biolink:CellularComponent cytoplasmic side of trans-Golgi network transport vesicle membrane The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm. go-plus.json external side of trans-Golgi network transport vesicle membrane http://purl.obolibrary.org/obo/GO_0098541 GO:0001633 biolink:MolecularActivity obsolete secretin-like receptor activity OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the secretin receptor. go-plus.json class B G protein coupled receptor|secretin-like receptor activity|class B orphan receptor activity|class B G-protein coupled receptor|class B GPCR http://purl.obolibrary.org/obo/GO_0001633 GO:0098542 biolink:BiologicalProcess defense response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. go-plus.json defence response to pathogen, incompatible interaction|defence response incompatible interaction|resistance response to pathogen|defense response, incompatible interaction http://purl.obolibrary.org/obo/GO_0098542 GO:0001634 biolink:MolecularActivity pituitary adenylate cyclase-activating polypeptide receptor activity A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide. go-plus.json pituitary adenylate cyclase-activating peptide receptor activity|pituitary adenylate cyclase activating polypeptide receptor|pituitary adenylate cyclase activating protein receptor activity|pituitary adenylate cyclase-activating polypeptide receptor activity|pituitary adenylyl cyclase activating protein receptor activity|PACAP receptor http://purl.obolibrary.org/obo/GO_0001634 GO:0098540 biolink:CellularComponent lumenal side of trans-Golgi network transport vesicle membrane The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen. go-plus.json internal side of trans-Golgi network transport vesicle membrane http://purl.obolibrary.org/obo/GO_0098540 GO:0001630 biolink:MolecularActivity obsolete GP40-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json GP40-like receptor activity http://purl.obolibrary.org/obo/GO_0001630 CHEBI:27573 biolink:ChemicalSubstance silicon atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27573 chebi_ph7_3 CHEBI:27574 biolink:ChemicalSubstance N(2)-succinyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27574 GO:1902159 biolink:BiologicalProcess regulation of cyclic nucleotide-gated ion channel activity Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity. go-plus.json regulation of cyclic nucleotide activated ion channel activity|regulation of cyclic nucleotide gated ion channel activity|regulation of cyclic nucleotide-activated ion channel activity http://purl.obolibrary.org/obo/GO_1902159 CHEBI:27576 biolink:ChemicalSubstance 19-hydroxyandrost-4-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_27576 chebi_ph7_3 GO:1902157 biolink:BiologicalProcess regulation of response to G2 DNA damage checkpoint signaling Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling. go-plus.json regulation of response to signal involved in G2/M transition DNA damage checkpoint|regulation of G2/M transition DNA damage checkpoint effector process http://purl.obolibrary.org/obo/GO_1902157 GO:1902158 biolink:BiologicalProcess positive regulation of response to G2 DNA damage checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling. go-plus.json up-regulation of response to signal involved in G2/M transition DNA damage checkpoint|up-regulation of G2/M transition DNA damage checkpoint effector process|upregulation of response to G2 DNA damage checkpoint signaling|activation of response to signal involved in G2/M transition DNA damage checkpoint|activation of G2/M transition DNA damage checkpoint effector process|positive regulation of response to signal involved in G2/M transition DNA damage checkpoint|positive regulation of G2/M transition DNA damage checkpoint effector process|activation of response to G2 DNA damage checkpoint signaling|up-regulation of response to G2 DNA damage checkpoint signaling|up regulation of response to signal involved in G2/M transition DNA damage checkpoint|up regulation of G2/M transition DNA damage checkpoint effector process|upregulation of response to signal involved in G2/M transition DNA damage checkpoint|upregulation of G2/M transition DNA damage checkpoint effector process|up regulation of response to G2 DNA damage checkpoint signaling http://purl.obolibrary.org/obo/GO_1902158 CHEBI:27570 biolink:ChemicalSubstance histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27570 GO:1902155 biolink:BiologicalProcess regulation of response to G1 DNA damage checkpoint signaling Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling. go-plus.json regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling http://purl.obolibrary.org/obo/GO_1902155 CHEBI:27571 biolink:ChemicalSubstance 3'-ketolactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27571 chebi_ph7_3 GO:1902156 biolink:BiologicalProcess positive regulation of response to G1 DNA damage checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling. go-plus.json upregulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|upregulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up-regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|upregulation of response to G1 DNA damage checkpoint signaling|activation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|positive regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|positive regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|activation of response to G1 DNA damage checkpoint signaling|up-regulation of response to G1 DNA damage checkpoint signaling|activation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|activation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up-regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|upregulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up-regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to G1 DNA damage checkpoint signaling http://purl.obolibrary.org/obo/GO_1902156 GO:1902164 biolink:BiologicalProcess positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. go-plus.json activation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator http://purl.obolibrary.org/obo/GO_1902164 GO:1902165 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. go-plus.json regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_1902165 GO:1902162 biolink:BiologicalProcess regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. go-plus.json http://purl.obolibrary.org/obo/GO_1902162 GO:1902163 biolink:BiologicalProcess negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. go-plus.json down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator http://purl.obolibrary.org/obo/GO_1902163 GO:1902160 biolink:BiologicalProcess negative regulation of cyclic nucleotide-gated ion channel activity Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity. go-plus.json negative regulation of cyclic nucleotide activated ion channel activity|down-regulation of cyclic nucleotide activated ion channel activity|down regulation of cyclic nucleotide-activated ion channel activity|downregulation of cyclic nucleotide-gated ion channel activity|inhibition of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide gated ion channel activity|down regulation of cyclic nucleotide-gated ion channel activity|negative regulation of cyclic nucleotide gated ion channel activity|downregulation of cyclic nucleotide activated ion channel activity|inhibition of cyclic nucleotide-gated ion channel activity|down regulation of cyclic nucleotide activated ion channel activity|downregulation of cyclic nucleotide gated ion channel activity|negative regulation of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide-activated ion channel activity|inhibition of cyclic nucleotide activated ion channel activity|down regulation of cyclic nucleotide gated ion channel activity|down-regulation of cyclic nucleotide-gated ion channel activity|inhibition of cyclic nucleotide gated ion channel activity|downregulation of cyclic nucleotide-activated ion channel activity http://purl.obolibrary.org/obo/GO_1902160 GO:1902161 biolink:BiologicalProcess positive regulation of cyclic nucleotide-gated ion channel activity Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity. go-plus.json activation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide-gated ion channel activity|up-regulation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide-activated ion channel activity|positive regulation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide activated ion channel activity|activation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide-gated ion channel activity|positive regulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide-activated ion channel activity|up regulation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide activated ion channel activity|activation of cyclic nucleotide-activated ion channel activity|activation of cyclic nucleotide-gated ion channel activity|up-regulation of cyclic nucleotide-gated ion channel activity|positive regulation of cyclic nucleotide-activated ion channel activity|upregulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide-activated ion channel activity http://purl.obolibrary.org/obo/GO_1902161 GO:0001639 biolink:MolecularActivity PLC activating G protein-coupled glutamate receptor activity A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system. go-plus.json group I metabotropic glutamate receptor activity|Group I metabotropic glutamate receptor|phospholipase C activating metabotropic glutamate receptor activity|PLC activating metabotropic glutamate receptor activity|PLC activating G-protein coupled glutamate receptor activity http://purl.obolibrary.org/obo/GO_0001639 GO:0098549 biolink:CellularComponent somatic ring canal A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects. go-plus.json http://purl.obolibrary.org/obo/GO_0098549 GO:0001635 biolink:MolecularActivity calcitonin gene-related peptide receptor activity Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity. Wikipedia:CALCRL go-plus.json calcitonin gene-related polypeptide receptor activity|CGRP receptor http://purl.obolibrary.org/obo/GO_0001635 GO:0098547 biolink:CellularComponent lumenal side of Golgi membrane The side of the Golgi membrane that faces the lumen. go-plus.json http://purl.obolibrary.org/obo/GO_0098547 GO:0098548 biolink:CellularComponent cytoplasmic side of Golgi membrane The side (leaflet) of the Golgi membrane that faces the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0098548 GO:0001636 biolink:MolecularActivity obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity http://purl.obolibrary.org/obo/GO_0001636 GO:0001637 biolink:MolecularActivity G protein-coupled chemoattractant receptor activity Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein chemoattractant receptor activity|G protein chemoattractant receptor activity|G-protein coupled chemoattractant receptor activity http://purl.obolibrary.org/obo/GO_0001637 GO:0098545 biolink:BiologicalProcess maintenance of protein complex location in cytoplasm Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0098545 GO:0098546 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098546 GO:0001638 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001638 GO:0098554 biolink:CellularComponent cytoplasmic side of endoplasmic reticulum membrane The side (leaflet) of the plasma membrane that faces the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0098554 GO:0001642 biolink:MolecularActivity group III metabotropic glutamate receptor activity A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001642 GO:0098555 biolink:CellularComponent lumenal side of rough endoplasmic reticulum membrane The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen. go-plus.json http://purl.obolibrary.org/obo/GO_0098555 GO:0001643 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001643 GO:0098552 biolink:CellularComponent side of membrane A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098552 GO:0001644 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001644 GO:0001645 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001645 GO:0098553 biolink:CellularComponent lumenal side of endoplasmic reticulum membrane The side (leaflet) of the plasma membrane that faces the lumen. go-plus.json http://purl.obolibrary.org/obo/GO_0098553 GO:0098550 biolink:CellularComponent lumenal side of early endosome membrane The side (leaflet) of the early endosome membrane that faces the lumen. go-plus.json internal side of early endosome membrane|internal leaflet of early endosome membrane http://purl.obolibrary.org/obo/GO_0098550 GO:0098551 biolink:CellularComponent lumenal side of late endosome membrane The side (leaflet) of the late endosome membrane that faces the lumen. go-plus.json internal leaflet of late endosome membrane|internal side of late endosome membrane http://purl.obolibrary.org/obo/GO_0098551 GO:0001640 biolink:MolecularActivity adenylate cyclase inhibiting G protein-coupled glutamate receptor activity Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity. go-plus.json adenylate cyclase inhibiting metabotropic glutamate receptor activity|adenylyl cyclase inhibiting metabotropic glutamate receptor activity http://purl.obolibrary.org/obo/GO_0001640 GO:0001641 biolink:MolecularActivity group II metabotropic glutamate receptor activity A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001641 CHEBI:27584 biolink:ChemicalSubstance aldosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27584 chebi_ph7_3 CHEBI:27585 biolink:ChemicalSubstance selenomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27585 CHEBI:27586 biolink:ChemicalSubstance beta-L-rhamnopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27586 chebi_ph7_3 GO:1902168 biolink:BiologicalProcess response to catechin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902168 GO:1902169 biolink:BiologicalProcess cellular response to catechin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902169 GO:1902166 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. go-plus.json down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_1902166 CHEBI:27582 biolink:ChemicalSubstance 16alpha-hydroxyandrost-4-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_27582 chebi_ph7_3 GO:1902167 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. go-plus.json up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|activation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_1902167 GO:1902175 biolink:BiologicalProcess regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway. go-plus.json regulation of intrinsic apoptotic signaling pathway in response to oxidative stress http://purl.obolibrary.org/obo/GO_1902175 GO:1902176 biolink:BiologicalProcess negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway. go-plus.json downregulation of intrinsic apoptotic signaling pathway in response to oxidative stress|down-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of intrinsic apoptotic signaling pathway in response to oxidative stress|down regulation of intrinsic apoptotic signaling pathway in response to oxidative stress http://purl.obolibrary.org/obo/GO_1902176 GO:1902173 biolink:BiologicalProcess negative regulation of keratinocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process. go-plus.json down regulation of keratinocyte apoptotic process|inhibition of keratinocyte apoptosis|inhibition of keratinocyte apoptotic process|down-regulation of keratinocyte apoptosis|negative regulation of keratinocyte apoptosis|down-regulation of keratinocyte apoptotic process|downregulation of keratinocyte apoptosis|down regulation of keratinocyte apoptosis|downregulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902173 GO:1902174 biolink:BiologicalProcess positive regulation of keratinocyte apoptotic process Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process. go-plus.json upregulation of keratinocyte apoptosis|upregulation of keratinocyte apoptotic process|up-regulation of keratinocyte apoptosis|up-regulation of keratinocyte apoptotic process|activation of keratinocyte apoptotic process|activation of keratinocyte apoptosis|positive regulation of keratinocyte apoptosis|up regulation of keratinocyte apoptosis|up regulation of keratinocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902174 CHEBI:27590 biolink:ChemicalSubstance 7-hydroxyflavanone 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27590 chebi_ph7_3 GO:1990707 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990707 GO:1902171 biolink:BiologicalProcess regulation of tocopherol cyclase activity Any process that modulates the frequency, rate or extent of tocopherol cyclase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902171 GO:1990708 biolink:BiologicalProcess conditioned place preference The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug. go-plus.json http://purl.obolibrary.org/obo/GO_1990708 GO:1902172 biolink:BiologicalProcess regulation of keratinocyte apoptotic process Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process. go-plus.json regulation of keratinocyte apoptosis http://purl.obolibrary.org/obo/GO_1902172 GO:1990709 biolink:BiologicalProcess presynaptic active zone organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone. go-plus.json presynaptic active zone organisation http://purl.obolibrary.org/obo/GO_1990709 GO:1902170 biolink:BiologicalProcess cellular response to reactive nitrogen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902170 GO:1990703 biolink:CellularComponent integral component of Golgi medial cisterna membrane The component of the Golgi medial membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral component of medial-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990703 GO:1990704 biolink:CellularComponent integral component of Golgi trans cisterna membrane The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral component of trans-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990704 GO:1990705 biolink:BiologicalProcess cholangiocyte proliferation The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. go-plus.json hepatoblast proliferation http://purl.obolibrary.org/obo/GO_1990705 GO:1990706 biolink:CellularComponent MAD1 complex A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). go-plus.json MAD1 homodimer http://purl.obolibrary.org/obo/GO_1990706 GO:0098558 biolink:CellularComponent lumenal side of smooth endoplasmic reticulum membrane The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen. go-plus.json http://purl.obolibrary.org/obo/GO_0098558 GO:0001646 biolink:MolecularActivity cAMP receptor activity Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json 3',5'-cAMP receptor activity|adenosine 3',5'-cyclophosphate receptor activity|class E G-protein coupled receptor|cyclic AMP receptor activity|class E GPCR|3',5' cAMP receptor activity|class E G protein coupled receptor http://purl.obolibrary.org/obo/GO_0001646 GO:0001647 biolink:MolecularActivity G protein-coupled cytokinin receptor activity Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G protein coupled cytokinin receptor activity|cytokinin receptor activity, G-protein coupled|G-protein coupled cytokinin receptor activity http://purl.obolibrary.org/obo/GO_0001647 GO:1990700 biolink:BiologicalProcess nucleolar chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin. go-plus.json nucleolar chromatin organisation|establishment or maintenance of nucleolar chromatin architecture http://purl.obolibrary.org/obo/GO_1990700 GO:0098559 biolink:CellularComponent cytoplasmic side of early endosome membrane The side (leaflet) of the early endosome membrane that faces the cytoplasm. go-plus.json external leaflet of early endosome membrane|external side of early endosome membrane http://purl.obolibrary.org/obo/GO_0098559 GO:1990701 biolink:CellularComponent integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral component of ERGIC membrane|integral component of ER-Golgi intermediate compartment membrane|integral component of endoplasmic reticulum-Golgi intermediate compartment membrane http://purl.obolibrary.org/obo/GO_1990701 GO:0098556 biolink:CellularComponent cytoplasmic side of rough endoplasmic reticulum membrane The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0098556 GO:0001648 biolink:MolecularActivity proteinase activated receptor activity A G protein-coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0001648 GO:0098557 biolink:CellularComponent cytoplasmic side of smooth endoplasmic reticulum membrane The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0098557 GO:1990702 biolink:CellularComponent integral component of Golgi cis cisterna membrane The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral component of cis-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990702 GO:0001649 biolink:BiologicalProcess osteoblast differentiation The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. go-plus.json osteoblast cell differentiation http://purl.obolibrary.org/obo/GO_0001649 GO:0001610 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001610 GO:0001611 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001611 GO:0001612 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001612 CHEBI:27555 biolink:ChemicalSubstance prostaglandin C2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27555 CHEBI:27551 biolink:ChemicalSubstance 5-methylcytosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27551 chebi_ph7_3 GO:1902179 biolink:BiologicalProcess verruculogen metabolic process The chemical reactions and pathways involving verruculogen. go-plus.json verruculogen metabolism http://purl.obolibrary.org/obo/GO_1902179 GO:1902177 biolink:BiologicalProcess positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway. go-plus.json up regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|activation of intrinsic apoptotic signaling pathway in response to oxidative stress|positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of intrinsic apoptotic signaling pathway in response to oxidative stress http://purl.obolibrary.org/obo/GO_1902177 GO:1902178 biolink:BiologicalProcess fibroblast growth factor receptor apoptotic signaling pathway An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR). go-plus.json fibroblast growth factor receptor signalling pathway involved in programmed cell death by apoptosis|FGFR signaling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in programmed cell death by apoptosis|FGF receptor signaling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in apoptotic programmed cell death|FGF receptor signaling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signalling pathway involved in type I programmed cell death|fibroblast growth factor receptor signalling pathway involved in signaling (initiator) caspase activity|FGFR signaling pathway involved in type I programmed cell death|FGF receptor signalling pathway involved in type I programmed cell death|fibroblast growth factor receptor signaling pathway involved in apoptotic program|FGFR signaling pathway involved in apoptosis|FGFR signaling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in apoptosis|FGF receptor signaling pathway involved in apoptotic program|fibroblast growth factor receptor signalling pathway involved in apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic cell death|FGFR signaling pathway involved in apoptotic cell death|FGF receptor signalling pathway involved in apoptotic cell death|FGF receptor signaling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in apoptotic process|FGFR signaling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic process|FGF receptor signalling pathway involved in apoptotic programmed cell death|FGFR signaling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signalling pathway involved in apoptotic programmed cell death|FGF receptor signaling pathway involved in type I programmed cell death|fibroblast growth factor receptor signaling pathway involved in type I programmed cell death|FGF receptor signaling pathway involved in signaling (initiator) caspase activity|FGFR signaling pathway involved in apoptotic program|FGF receptor signalling pathway involved in apoptotic program|fibroblast growth factor receptor signaling pathway involved in signaling (initiator) caspase activity|fibroblast growth factor receptor signalling pathway involved in apoptotic program|FGF receptor signaling pathway involved in apoptotic cell death|fibroblast growth factor receptor signaling pathway involved in apoptotic cell death|fibroblast growth factor receptor signaling pathway involved in apoptosis|fibroblast growth factor receptor signaling pathway involved in apoptotic process|FGF receptor signaling pathway involved in apoptosis http://purl.obolibrary.org/obo/GO_1902178 UBERON:0009117 biolink:AnatomicalEntity indifferent gonad A gonad prior to differentiating into a definitive testis or ovary. go-plus.json gonad rudiment http://purl.obolibrary.org/obo/UBERON_0009117 GO:1902186 biolink:BiologicalProcess regulation of viral release from host cell Any process that modulates the frequency, rate or extent of viral release from host cell. go-plus.json regulation of viral shedding|regulation of viral exit|regulation of release of virus from host|regulation of viral release http://purl.obolibrary.org/obo/GO_1902186 GO:1902187 biolink:BiologicalProcess negative regulation of viral release from host cell Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell. go-plus.json down regulation of viral shedding|inhibition of release of virus from host|down-regulation of viral release|negative regulation of viral release|down-regulation of viral exit|negative regulation of viral exit|inhibition of viral shedding|down-regulation of viral release from host cell|downregulation of viral exit|negative regulation of release of virus from host|down-regulation of release of virus from host|downregulation of viral release from host cell|inhibition of viral release|down-regulation of viral shedding|negative regulation of viral shedding|down regulation of viral exit|down regulation of viral release from host cell|inhibition of viral release from host cell|downregulation of release of virus from host|down regulation of viral release|inhibition of viral exit|downregulation of viral shedding|down regulation of release of virus from host|downregulation of viral release http://purl.obolibrary.org/obo/GO_1902187 GO:1902184 biolink:BiologicalProcess negative regulation of shoot apical meristem development Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development. go-plus.json inhibition of shoot apical meristem development|inhibition of primary shoot meristem development|negative regulation of promeristem development|down-regulation of promeristem development|inhibition of SAM development|down regulation of shoot apical meristem development|inhibition of promeristem development|down-regulation of primary shoot meristem development|negative regulation of primary shoot meristem development|downregulation of shoot apical meristem development|down regulation of SAM development|downregulation of SAM development|down regulation of promeristem development|downregulation of primary shoot meristem development|down-regulation of shoot apical meristem development|downregulation of promeristem development|down regulation of primary shoot meristem development|down-regulation of SAM development|negative regulation of SAM development http://purl.obolibrary.org/obo/GO_1902184 GO:1902185 biolink:BiologicalProcess positive regulation of shoot apical meristem development Any process that activates or increases the frequency, rate or extent of shoot apical meristem development. go-plus.json positive regulation of promeristem development|activation of SAM development|up-regulation of shoot apical meristem development|activation of promeristem development|up-regulation of SAM development|up-regulation of primary shoot meristem development|up-regulation of promeristem development|upregulation of shoot apical meristem development|activation of primary shoot meristem development|upregulation of SAM development|positive regulation of primary shoot meristem development|upregulation of promeristem development|up regulation of shoot apical meristem development|up regulation of primary shoot meristem development|activation of shoot apical meristem development|up regulation of SAM development|positive regulation of SAM development|up regulation of promeristem development|upregulation of primary shoot meristem development http://purl.obolibrary.org/obo/GO_1902185 GO:1902182 biolink:BiologicalProcess shoot apical meristem development The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure. go-plus.json promeristem development|primary shoot meristem development|SAM development http://purl.obolibrary.org/obo/GO_1902182 GO:1902183 biolink:BiologicalProcess regulation of shoot apical meristem development Any process that modulates the frequency, rate or extent of shoot apical meristem development. go-plus.json regulation of SAM development|regulation of promeristem development|regulation of primary shoot meristem development http://purl.obolibrary.org/obo/GO_1902183 GO:1902180 biolink:BiologicalProcess verruculogen catabolic process The chemical reactions and pathways resulting in the breakdown of verruculogen. go-plus.json verruculogen breakdown|verruculogen degradation|verruculogen catabolism http://purl.obolibrary.org/obo/GO_1902180 GO:1902181 biolink:BiologicalProcess verruculogen biosynthetic process The chemical reactions and pathways resulting in the formation of verruculogen. go-plus.json verruculogen biosynthesis|verruculogen anabolism|verruculogen synthesis|verruculogen formation http://purl.obolibrary.org/obo/GO_1902181 GO:0001617 biolink:MolecularActivity obsolete growth hormone secretagogue-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json growth hormone secretagogue-like receptor activity http://purl.obolibrary.org/obo/GO_0001617 OBA:0007000 biolink:OntologyClass DNA stability The macromolecular stability of a DNA. go-plus.json macromolecular stability of DNA http://purl.obolibrary.org/obo/OBA_0007000 GO:0001618 biolink:MolecularActivity virus receptor activity Combining with a virus component and mediating entry of the virus into the cell. go-plus.json viral receptor activity http://purl.obolibrary.org/obo/GO_0001618 goslim_chembl GO:0001619 biolink:MolecularActivity obsolete lysosphingolipid and lysophosphatidic acid receptor activity OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity. go-plus.json lysosphingolipid and lysophosphatidic acid receptor activity http://purl.obolibrary.org/obo/GO_0001619 GO:0001613 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001613 GO:0001614 biolink:MolecularActivity purinergic nucleotide receptor activity Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json purinoreceptor|P2 receptor|purinergic receptor activity|purinoceptor http://purl.obolibrary.org/obo/GO_0001614 UBERON:0009114 biolink:AnatomicalEntity cervical thymus A mature thymus that is entirely part of the cervical region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009114 UBERON:0009115 biolink:AnatomicalEntity thoracic thymus A mature thymus that is entirely part of thoracic region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009115 GO:0001615 biolink:MolecularActivity obsolete thyrotropin releasing hormone and secretagogue-like receptors activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json thyrotropin releasing hormone and secretagogue-like receptors activity http://purl.obolibrary.org/obo/GO_0001615 GO:0001616 biolink:MolecularActivity growth hormone secretagogue receptor activity Combining with ghrelin to initiate a change in cell activity. go-plus.json ghrelin receptor activity http://purl.obolibrary.org/obo/GO_0001616 GO:0001620 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001620 GO:0001621 biolink:MolecularActivity G protein-coupled ADP receptor activity Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json K101 receptor|ADP receptor activity|ADP-activated adenosine receptor activity|platelet ADP receptor activity|ADP-activated nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0001621 GO:0001622 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001622 GO:0001623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001623 CHEBI:52507 biolink:ChemicalSubstance haloindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_52507 CHEBI:52500 biolink:ChemicalSubstance cobyrinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52500 CHEBI:52501 biolink:ChemicalSubstance 2-hydroxycarbonyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_52501 chebi_ph7_3 CHEBI:27568 biolink:ChemicalSubstance selenium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27568 chebi_ph7_3 CHEBI:27569 biolink:ChemicalSubstance arabinogalactan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27569 CHEBI:27562 biolink:ChemicalSubstance 20-hydroxy-20-oxoleukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27562 CHEBI:27563 biolink:ChemicalSubstance arsenic atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27563 chebi_ph7_3 CHEBI:27565 biolink:ChemicalSubstance 4-aminosalicylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27565 CHEBI:52508 biolink:ChemicalSubstance chloroindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_52508 GO:1902188 biolink:BiologicalProcess positive regulation of viral release from host cell Any process that activates or increases the frequency, rate or extent of viral release from host cell. go-plus.json upregulation of release of virus from host|up-regulation of viral exit|up regulation of viral release|up-regulation of viral release from host cell|positive regulation of viral release|activation of viral release from host cell|upregulation of viral shedding|activation of viral exit|activation of viral release|up-regulation of release of virus from host|positive regulation of viral exit|up-regulation of viral shedding|up-regulation of viral release|up regulation of viral exit|up regulation of viral release from host cell|activation of release of virus from host|activation of viral shedding|positive regulation of release of virus from host|upregulation of viral release|up regulation of release of virus from host|positive regulation of viral shedding|upregulation of viral exit|upregulation of viral release from host cell|up regulation of viral shedding http://purl.obolibrary.org/obo/GO_1902188 CHEBI:27560 biolink:ChemicalSubstance boron atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27560 chebi_ph7_3 CHEBI:27561 biolink:ChemicalSubstance oxirane go-plus.json http://purl.obolibrary.org/obo/CHEBI_27561 chebi_ph7_3 GO:1902189 biolink:BiologicalProcess 2-methylbutanoyl-CoA(4-) metabolic process The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-). go-plus.json 2-methylbutanoyl-CoA(4-) metabolism http://purl.obolibrary.org/obo/GO_1902189 GO:1902197 biolink:BiologicalProcess isovaleryl-CoA(4-) biosynthetic process The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-). go-plus.json isovaleryl-CoA(4-) anabolism|isovaleryl-CoA(4-) biosynthesis|isovaleryl-CoA(4-) synthesis|isovaleryl-CoA(4-) formation http://purl.obolibrary.org/obo/GO_1902197 GO:1902198 biolink:BiologicalProcess 3-methylbut-2-enoyl-CoA(4-) metabolic process The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-). go-plus.json 3-methylbut-2-enoyl-CoA(4-) metabolism http://purl.obolibrary.org/obo/GO_1902198 GO:1902195 biolink:BiologicalProcess isovaleryl-CoA(4-) metabolic process The chemical reactions and pathways involving isovaleryl-CoA(4-). go-plus.json isovaleryl-CoA(4-) metabolism http://purl.obolibrary.org/obo/GO_1902195 GO:1902196 biolink:BiologicalProcess isovaleryl-CoA(4-) catabolic process The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-). go-plus.json isovaleryl-CoA(4-) catabolism|isovaleryl-CoA(4-) degradation|isovaleryl-CoA(4-) breakdown http://purl.obolibrary.org/obo/GO_1902196 GO:1902193 biolink:BiologicalProcess 2-methylbut-2-enoyl-CoA(4-) catabolic process The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-). go-plus.json 2-methylbut-2-enoyl-CoA(4-) catabolism|2-methylbut-2-enoyl-CoA(4-) degradation|2-methylbut-2-enoyl-CoA(4-) breakdown http://purl.obolibrary.org/obo/GO_1902193 GO:1902194 biolink:BiologicalProcess 2-methylbut-2-enoyl-CoA(4-) biosynthetic process The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-). go-plus.json 2-methylbut-2-enoyl-CoA(4-) biosynthesis|2-methylbut-2-enoyl-CoA(4-) anabolism|2-methylbut-2-enoyl-CoA(4-) synthesis|2-methylbut-2-enoyl-CoA(4-) formation http://purl.obolibrary.org/obo/GO_1902194 GO:1902191 biolink:BiologicalProcess 2-methylbutanoyl-CoA(4-) biosynthetic process The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-). go-plus.json 2-methylbutanoyl-CoA(4-) anabolism|2-methylbutanoyl-CoA(4-) synthesis|2-methylbutanoyl-CoA(4-) formation|2-methylbutanoyl-CoA(4-) biosynthesis http://purl.obolibrary.org/obo/GO_1902191 GO:1902192 biolink:BiologicalProcess 2-methylbut-2-enoyl-CoA(4-) metabolic process The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-). go-plus.json 2-methylbut-2-enoyl-CoA(4-) metabolism http://purl.obolibrary.org/obo/GO_1902192 GO:0001628 biolink:MolecularActivity obsolete gastropyloric receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json gastropyloric receptor activity|GPR receptor http://purl.obolibrary.org/obo/GO_0001628 GO:1902190 biolink:BiologicalProcess 2-methylbutanoyl-CoA(4-) catabolic process The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-). go-plus.json 2-methylbutanoyl-CoA(4-) degradation|2-methylbutanoyl-CoA(4-) breakdown|2-methylbutanoyl-CoA(4-) catabolism http://purl.obolibrary.org/obo/GO_1902190 GO:0001629 biolink:MolecularActivity obsolete G-protein receptor 45-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json G protein receptor 45-like receptor activity|GPR45-like receptor|G-protein receptor 45-like receptor activity http://purl.obolibrary.org/obo/GO_0001629 GO:0001624 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001624 GO:0001625 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001625 GO:0001626 biolink:MolecularActivity nociceptin receptor activity Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json OFQ receptor activity|ORPH receptor|X-opioid receptor activity|nociceptin/orphanin-FQ receptor activity|orphanin-FQ receptor activity http://purl.obolibrary.org/obo/GO_0001626 GO:0001627 biolink:MolecularActivity obsolete leucine-rich G-protein receptor-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json leucine-rich G-protein receptor-like receptor activity|leucine-rich G protein receptor-like receptor activity|LGR-like receptor http://purl.obolibrary.org/obo/GO_0001627 CHEBI:27537 biolink:ChemicalSubstance trans-oct-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27537 GO:0098587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098587 GO:0098588 biolink:CellularComponent bounding membrane of organelle The lipid bilayer that forms the outer-most layer of an organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0098588 GO:0098585 biolink:CellularComponent host cell synaptic vesicle membrane The lipid bilayer surrounding a host synaptic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0098585 CHEBI:27539 biolink:ChemicalSubstance isatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27539 chebi_ph7_3 GO:0098586 biolink:BiologicalProcess cellular response to virus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. go-plus.json http://purl.obolibrary.org/obo/GO_0098586 CHEBI:27533 biolink:ChemicalSubstance beta-zeacarotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27533 chebi_ph7_3 GO:0098583 biolink:BiologicalProcess learned vocalization behavior A vocalization behavior that is the result of learning. go-plus.json http://purl.obolibrary.org/obo/GO_0098583 GO:0098584 biolink:CellularComponent host cell synaptic vesicle A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098584 GO:0098581 biolink:BiologicalProcess detection of external biotic stimulus The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated. go-plus.json detection of exogenous biotic stimulus http://purl.obolibrary.org/obo/GO_0098581 CHEBI:27535 biolink:ChemicalSubstance alpha-D-mannoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27535 chebi_ph7_3 GO:0098582 biolink:BiologicalProcess innate vocalization behavior A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur. go-plus.json http://purl.obolibrary.org/obo/GO_0098582 GO:0098580 biolink:CellularComponent obsolete chromatin of active sex chromosome OBSOLETE. Chromatin that is part of an active sex chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098580 CHEBI:27530 biolink:ChemicalSubstance 4-hydroxy-2-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27530 CHEBI:27532 biolink:ChemicalSubstance L-cysteine thioether go-plus.json http://purl.obolibrary.org/obo/CHEBI_27532 GO:1902199 biolink:BiologicalProcess 3-methylbut-2-enoyl-CoA(4-) catabolic process The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-). go-plus.json 3-methylbut-2-enoyl-CoA(4-) breakdown|3-methylbut-2-enoyl-CoA(4-) catabolism|3-methylbut-2-enoyl-CoA(4-) degradation http://purl.obolibrary.org/obo/GO_1902199 GO:0098589 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098589 GO:0098598 biolink:BiologicalProcess learned vocalization behavior or vocal learning Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned. go-plus.json http://purl.obolibrary.org/obo/GO_0098598 GO:0098599 biolink:MolecularActivity palmitoyl hydrolase activity Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate. Reactome:R-HSA-5690046|Reactome:R-HSA-9027670 go-plus.json http://purl.obolibrary.org/obo/GO_0098599 GO:0098596 biolink:BiologicalProcess imitative learning Learning in which new behaviors are acquired through imitation. Wikipedia:Imitative_learning|Wikipedia:Observational_learning#Observational_learning_compared_to_imitation go-plus.json http://purl.obolibrary.org/obo/GO_0098596 GO:0001600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001600 GO:0098597 biolink:BiologicalProcess observational learning Learning that occurs through observing the behavior of others. Wikipedia:Observational_learning go-plus.json http://purl.obolibrary.org/obo/GO_0098597 GO:0001601 biolink:MolecularActivity peptide YY receptor activity Combining with gut peptide YY to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001601 GO:0098594 biolink:CellularComponent mucin granule A secretory granule that contains mucin. go-plus.json http://purl.obolibrary.org/obo/GO_0098594 CHEBI:27544 biolink:ChemicalSubstance 3,5-dibromo-4-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27544 CHEBI:27545 biolink:ChemicalSubstance 2,5-dichlorohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27545 chebi_ph7_3 GO:0098595 biolink:CellularComponent perivitelline space The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane). go-plus.json http://purl.obolibrary.org/obo/GO_0098595 GO:0098592 biolink:CellularComponent cytoplasmic side of apical plasma membrane The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0098592 CHEBI:27547 biolink:ChemicalSubstance zeaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27547 chebi_ph7_3 GO:0098593 biolink:CellularComponent goblet cell theca A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel. go-plus.json http://purl.obolibrary.org/obo/GO_0098593 GO:0098590 biolink:CellularComponent plasma membrane region A membrane that is a (regional) part of the plasma membrane. go-plus.json region of plasma membrane http://purl.obolibrary.org/obo/GO_0098590 gocheck_do_not_manually_annotate CHEBI:27540 biolink:ChemicalSubstance hexanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27540 CHEBI:27541 biolink:ChemicalSubstance 3',5'-cyclic IMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_27541 GO:0098591 biolink:CellularComponent external side of apical plasma membrane The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0098591 CHEBI:27543 biolink:ChemicalSubstance 9H-carbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_27543 chebi_ph7_3 GO:0001606 biolink:MolecularActivity obsolete GPR37/endothelin B-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json GPR37/endothelin B-like receptor activity http://purl.obolibrary.org/obo/GO_0001606 GO:0001607 biolink:MolecularActivity neuromedin U receptor activity Combining with neuromedin U to initiate a change in cell activity. go-plus.json NMUR activity http://purl.obolibrary.org/obo/GO_0001607 GO:0001608 biolink:MolecularActivity G protein-coupled nucleotide receptor activity Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein coupled nucleotide receptor activity|nucleotide receptor activity, G-protein coupled|nucleotide receptor activity, G protein coupled|G protein coupled nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0001608 GO:0001609 biolink:MolecularActivity G protein-coupled adenosine receptor activity Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein-coupled A2B adenosine receptor activity|A1 adenosine receptor activity, G protein coupled|G protein coupled A3 adenosine receptor activity|A2A adenosine receptor activity, G protein coupled|G-protein-coupled A2A adenosine receptor activity|A2B adenosine receptor activity, G protein coupled|A3 adenosine receptor activity, G protein coupled|G protein coupled A1 adenosine receptor activity|G protein coupled A2B adenosine receptor activity|G-protein-coupled A3 adenosine receptor activity|G protein coupled A2A adenosine receptor activity|G-protein-coupled A1 adenosine receptor activity|G-protein coupled adenosine receptor activity|A1 adenosine receptor activity, G-protein coupled|A2A adenosine receptor activity, G-protein coupled|A2B adenosine receptor activity, G-protein coupled|A3 adenosine receptor activity, G-protein coupled|P1 receptor|adenosine receptor activity, G-protein coupled|adenosine receptor activity, G protein coupled|adenosine nucleotide receptor|G protein coupled adenosine receptor activity http://purl.obolibrary.org/obo/GO_0001609 GO:0001602 biolink:MolecularActivity pancreatic polypeptide receptor activity Combining with pancreatic polypeptide PP to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001602 GO:0001603 biolink:MolecularActivity obsolete vasopressin-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json vasopressin-like receptor activity http://purl.obolibrary.org/obo/GO_0001603 GO:0001604 biolink:MolecularActivity urotensin II receptor activity Combining with urotensin II to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001604 GO:0001605 biolink:MolecularActivity adrenomedullin receptor activity Combining with adrenomedullin to initiate a change in cell activity. go-plus.json G10D receptor http://purl.obolibrary.org/obo/GO_0001605 GO:0050543 biolink:MolecularActivity icosatetraenoic acid binding Binding to icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule. go-plus.json eicosatetraenoic acid binding http://purl.obolibrary.org/obo/GO_0050543 GO:0050544 biolink:MolecularActivity arachidonic acid binding Binding to arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. go-plus.json arachidonate binding http://purl.obolibrary.org/obo/GO_0050544 GO:0050541 biolink:MolecularActivity beta,beta-carotene-9',10'-dioxygenase activity Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone. go-plus.json b,b-carotene-9',10'-dioxygenase activity http://purl.obolibrary.org/obo/GO_0050541 GO:0050542 biolink:MolecularActivity icosanoid binding Binding to icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids. go-plus.json eicosanoid binding http://purl.obolibrary.org/obo/GO_0050542 GO:0050547 biolink:MolecularActivity vanillin synthase activity Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin. RHEA:18725|EC:4.1.2.61|KEGG_REACTION:R05773|MetaCyc:4.1.2.41-RXN go-plus.json 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)|3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming) http://purl.obolibrary.org/obo/GO_0050547 GO:0050548 biolink:MolecularActivity trans-feruloyl-CoA hydratase activity Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA. MetaCyc:4.2.1.101-RXN|EC:4.2.1.101|RHEA:14517 go-plus.json trans-feruloyl-CoA hydro-lyase activity|4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming) http://purl.obolibrary.org/obo/GO_0050548 GO:0050545 biolink:MolecularActivity sulfopyruvate decarboxylase activity Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde. MetaCyc:R231-RXN|KEGG_REACTION:R05774|RHEA:20948|EC:4.1.1.79 go-plus.json sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)|sulfopyruvate carboxy-lyase activity|sulphopyruvate decarboxylase activity http://purl.obolibrary.org/obo/GO_0050545 GO:0050546 biolink:MolecularActivity 4-hydroxyphenylpyruvate decarboxylase activity Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2). EC:4.1.1.80|KEGG_REACTION:R03341|RHEA:18697|MetaCyc:4.1.1.80-RXN go-plus.json 4-hydroxyphenylpyruvate carboxy-lyase activity|4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming) http://purl.obolibrary.org/obo/GO_0050546 GO:0050549 biolink:MolecularActivity cyclohexyl-isocyanide hydratase activity Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O. MetaCyc:4.2.1.103-RXN|KEGG_REACTION:R05771|EC:4.2.1.103|RHEA:18197|UM-BBD_reactionID:r1029 go-plus.json N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)|isonitrile hydratase activity|N-cyclohexylformamide hydro-lyase activity http://purl.obolibrary.org/obo/GO_0050549 CL:0000240 biolink:Cell stratified squamous epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000240 CL:0000243 biolink:Cell obsolete glial cell (sensu Vertebrata) A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. go-plus.json http://purl.obolibrary.org/obo/CL_0000243 CL:0000244 biolink:Cell transitional epithelial cell A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. go-plus.json http://purl.obolibrary.org/obo/CL_0000244 CHEBI:76481 biolink:ChemicalSubstance (3R,23Z,26Z,29Z,32Z,35Z)-3-hydroxyoctatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76481 chebi_ph7_3 CL:0000247 biolink:Cell Rohon-Beard neuron Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. go-plus.json Rohon Beard cell|RB neuron|Rohon-Beard cell http://purl.obolibrary.org/obo/CL_0000247 CHEBI:76485 biolink:ChemicalSubstance (R)-3-hydroxytriacontanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76485 CHEBI:76483 biolink:ChemicalSubstance (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76483 chebi_ph7_3 CHEBI:76484 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76484 chebi_ph7_3 GO:0050540 biolink:MolecularActivity 2-aminomuconate deaminase activity Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+). MetaCyc:3.5.99.5-RXN|EC:3.5.99.5|RHEA:20996|KEGG_REACTION:R03887 go-plus.json 2-aminomuconate aminohydrolase activity http://purl.obolibrary.org/obo/GO_0050540 GO:0050554 biolink:MolecularActivity abietadiene synthase activity Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate. EC:4.2.3.18|RHEA:13873|KEGG_REACTION:R06301|MetaCyc:4.2.3.18-RXN go-plus.json copalyl-diphosphate diphosphate-lyase (cyclizing)|(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)|abietadiene cyclase activity http://purl.obolibrary.org/obo/GO_0050554 GO:0050555 biolink:MolecularActivity 2-hydroxypropyl-CoM lyase activity Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane. EC:4.4.1.23|MetaCyc:4.2.99.19-RXN|RHEA:19421|UM-BBD_enzymeID:e0538 go-plus.json 2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|epoxyalkane:2-mercaptoethanesulfonate transferase activity|(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|epoxyalkyl:CoM transferase activity|epoxyalkane:coenzyme M transferase activity|coenzyme M-epoxyalkane ligase activity|(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)|epoxypropyl:CoM transferase activity|epoxypropane:coenzyme M transferase activity|epoxyalkane:CoM transferase activity|EaCoMT activity http://purl.obolibrary.org/obo/GO_0050555 GO:0050552 biolink:MolecularActivity (4S)-limonene synthase activity Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate. EC:4.2.3.16|RHEA:12869|MetaCyc:4.2.3.16-RXN go-plus.json 4S-(-)-limonene synthase activity|geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]|geranyldiphosphate diphosphate lyase (limonene forming)|(-)-(4S)-limonene synthase activity http://purl.obolibrary.org/obo/GO_0050552 GO:0050553 biolink:MolecularActivity taxadiene synthase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene. RHEA:20912|EC:4.2.3.17|KEGG_REACTION:R06305|MetaCyc:4.2.3.17-RXN go-plus.json geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)|taxa-4(5),11(12)-diene synthase activity http://purl.obolibrary.org/obo/GO_0050553 GO:0050558 biolink:MolecularActivity maltose epimerase activity Catalysis of the reaction: alpha-maltose = beta-maltose. MetaCyc:5.1.3.21-RXN|RHEA:21228|KEGG_REACTION:R07319|EC:5.1.3.21 go-plus.json maltose 1-epimerase activity http://purl.obolibrary.org/obo/GO_0050558 GO:0050559 biolink:MolecularActivity copalyl diphosphate synthase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate. MetaCyc:RXN-4861|RHEA:24316|EC:5.5.1.12|KEGG_REACTION:R06298 go-plus.json (+)-copalyl-diphosphate lyase (decyclizing)|diterpene cyclase activity http://purl.obolibrary.org/obo/GO_0050559 GO:0050556 biolink:MolecularActivity deacetylisoipecoside synthase activity Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin. RHEA:21756|MetaCyc:4.3.3.3-RXN|EC:4.3.3.3|KEGG_REACTION:R05750 go-plus.json deacetylisoipecoside dopamine-lyase (secologanin-forming)|deacetylisoipecoside dopamine-lyase activity http://purl.obolibrary.org/obo/GO_0050556 GO:0050557 biolink:MolecularActivity deacetylipecoside synthase activity Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin. KEGG_REACTION:R05749|MetaCyc:4.3.3.4-RXN|EC:4.3.3.4|RHEA:12296 go-plus.json deacetylipecoside dopamine-lyase (secologanin-forming)|deacetylipecoside dopamine-lyase activity http://purl.obolibrary.org/obo/GO_0050557 CL:0000253 biolink:Cell eurydendroid cell go-plus.json http://purl.obolibrary.org/obo/CL_0000253 CHEBI:76492 biolink:ChemicalSubstance trans-2-triacontenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76492 CL:0000255 biolink:Cell eukaryotic cell go-plus.json http://purl.obolibrary.org/obo/CL_0000255 CHEBI:76493 biolink:ChemicalSubstance (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76493 chebi_ph7_3 CHEBI:76490 biolink:ChemicalSubstance trans-octacos-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76490 CHEBI:76491 biolink:ChemicalSubstance (3R,8Z,11Z,14Z,17Z,20Z,23Z)-hydroxyhexacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76491 chebi_ph7_3 CHEBI:76496 biolink:ChemicalSubstance (3R,12Z,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76496 chebi_ph7_3 CHEBI:76497 biolink:ChemicalSubstance (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76497 chebi_ph7_3 CHEBI:76494 biolink:ChemicalSubstance (3R,10Z,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76494 chebi_ph7_3 CHEBI:76495 biolink:ChemicalSubstance (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76495 chebi_ph7_3 GO:0050550 biolink:MolecularActivity pinene synthase activity Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate. EC:4.2.3.14|MetaCyc:4.2.3.14-RXN go-plus.json geranyldiphosphate diphosphate lyase (pinene forming)|beta-geraniolene synthase activity|(-)-(1S,5S)-pinene synthase activity|geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming) http://purl.obolibrary.org/obo/GO_0050550 GO:0050551 biolink:MolecularActivity myrcene synthase activity Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene. MetaCyc:RXN-5110|KEGG_REACTION:R02009|EC:4.2.3.15|RHEA:16965 go-plus.json geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity http://purl.obolibrary.org/obo/GO_0050551 CHEBI:76498 biolink:ChemicalSubstance coral metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76498 GO:0050565 biolink:MolecularActivity aerobactin synthase activity Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate. RHEA:11760|MetaCyc:6.3.2.27-RXN|KEGG_REACTION:R04357 go-plus.json citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)|citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0050565 GO:0001598 biolink:MolecularActivity obsolete chemokine receptor-like receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json chemokine receptor-like receptor activity http://purl.obolibrary.org/obo/GO_0001598 GO:0050566 biolink:MolecularActivity asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP. Wikipedia:Asparaginyl-tRNA_synthase_(glutamine-hydrolysing)|MetaCyc:6.3.5.6-RXN|EC:6.3.5.6|RHEA:14513 go-plus.json Asp-tRNAAsn amidotransferase activity|asparaginyl-tRNA synthase (glutamine-hydrolysing)|aspartyl-tRNAAsn amidotransferase activity|Asp-tRNA(Asn) amidotransferase activity|aspartyl-tRNA(Asn) amidotransferase activity|aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|Asp-AdT activity http://purl.obolibrary.org/obo/GO_0050566 GO:0001599 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001599 GO:0050563 biolink:MolecularActivity trans-feruloyl-CoA synthase activity Catalysis of the reaction: ATP + CoA + trans-ferulate = (E)-feruloyl-CoA + ADP + phosphate. RHEA:19389|MetaCyc:6.2.1.34-RXN|EC:6.2.1.34 go-plus.json trans-ferulate:CoASH ligase (ATP-hydrolysing)|ferulate-CoA ligase activity|trans-feruloyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0050563 GO:0050564 biolink:MolecularActivity N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+). KEGG_REACTION:R04870|RHEA:23196|MetaCyc:6.3.2.26-RXN|EC:6.3.2.26 go-plus.json L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)|L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity|ACV synthetase activity|L-alpha-aminoadipyl-cysteinyl-valine synthetase activity http://purl.obolibrary.org/obo/GO_0050564 GO:0050569 biolink:MolecularActivity glycolaldehyde dehydrogenase activity Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH. RHEA:20001|MetaCyc:GLYCOLALD-DEHYDROG-RXN|EC:1.2.1.21|KEGG_REACTION:R01333 go-plus.json glycol aldehyde dehydrogenase activity|glycolaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050569 GO:0001594 biolink:MolecularActivity trace-amine receptor activity Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0001594 GO:0001595 biolink:MolecularActivity angiotensin receptor activity Combining with angiotensin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001595 GO:0050567 biolink:MolecularActivity glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP. Wikipedia:Glutaminyl-tRNA_synthase_(glutamine-hydrolysing)|RHEA:17521|MetaCyc:6.3.5.7-RXN|EC:6.3.5.7 go-plus.json Glu-tRNAGln amidotransferase activity|glutamyl-tRNA(Gln) amidotransferase activity|Glu-AdT activity|glutaminyl-tRNA synthase (glutamine-hydrolysing)|glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)|glutamyl-tRNAGln amidotransferase activity|Glu-tRNA(Gln) amidotransferase activity|Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0050567 GO:0001596 biolink:MolecularActivity angiotensin type I receptor activity An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms. go-plus.json PLC-activating angiotensin receptor activity http://purl.obolibrary.org/obo/GO_0001596 GO:0050568 biolink:MolecularActivity protein-glutamine glutaminase activity Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3. RHEA:16441|MetaCyc:CHEBDEAMID-RXN|EC:3.5.1.44 go-plus.json peptidylglutaminase II|glutaminylpeptide glutaminase activity|protein-L-glutamine amidohydrolase activity|glutaminyl-peptide glutaminase activity|destabilase activity|peptidoglutaminase II activity http://purl.obolibrary.org/obo/GO_0050568 GO:0001597 biolink:MolecularActivity obsolete apelin-like receptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json APJ-like receptor|apelin-like receptor http://purl.obolibrary.org/obo/GO_0001597 CL:0000226 biolink:Cell single nucleate cell A cell with a single nucleus. go-plus.json http://purl.obolibrary.org/obo/CL_0000226 GO:0001590 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001590 GO:0001591 biolink:MolecularActivity dopamine neurotransmitter receptor activity, coupled via Gi/Go Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity. go-plus.json dopamine D4 receptor activity|dopamine D3 receptor activity|dopamine D2 receptor activity http://purl.obolibrary.org/obo/GO_0001591 CL:0000227 biolink:Cell binucleate cell go-plus.json http://purl.obolibrary.org/obo/CL_0000227 CL:0000228 biolink:Cell multinucleate cell A cell with more than one nucleus. go-plus.json syncytium|syncytial cell|syncitium http://purl.obolibrary.org/obo/CL_0000228 GO:0001592 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001592 GO:0001593 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001593 CHEBI:52490 biolink:ChemicalSubstance cobalt-precorrin-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_52490 CL:0000221 biolink:Cell ectodermal cell A cell of the outer of the three germ layers of the embryo. go-plus.json ectoderm cell http://purl.obolibrary.org/obo/CL_0000221 CHEBI:52491 biolink:ChemicalSubstance cobalt-sirohydrochlorin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52491 CL:0000222 biolink:Cell mesodermal cell A cell of the middle germ layer of the embryo. go-plus.json mesoblast|mesoderm cell http://purl.obolibrary.org/obo/CL_0000222 CL:0000223 biolink:Cell endodermal cell A cell of the inner of the three germ layers of the embryo. go-plus.json endoderm cell http://purl.obolibrary.org/obo/CL_0000223 CL:0000225 biolink:Cell anucleate cell A cell that lacks a nucleus. go-plus.json non-nucleated cell http://purl.obolibrary.org/obo/CL_0000225 CHEBI:52499 biolink:ChemicalSubstance cob(II)yrinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52499 GO:0050561 biolink:MolecularActivity glutamate-tRNA(Gln) ligase activity Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP. RHEA:18397|MetaCyc:6.1.1.24-RXN|EC:6.1.1.24 go-plus.json L-glutamate:tRNAGlx ligase (AMP-forming)|nondiscriminating glutamyl-tRNA synthetase activity|glutamate-tRNAGln ligase activity http://purl.obolibrary.org/obo/GO_0050561 GO:0050562 biolink:MolecularActivity lysine-tRNA(Pyl) ligase activity Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP. MetaCyc:6.1.1.25-RXN go-plus.json lysine-tRNAPyl ligase activity|L-lysine:tRNAPyl ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0050562 GO:0050560 biolink:MolecularActivity aspartate-tRNA(Asn) ligase activity Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP. MetaCyc:6.1.1.23-RXN|EC:6.1.1.23|RHEA:18349 go-plus.json nondiscriminating aspartyl-tRNA synthetase activity|L-aspartate:tRNAAsx ligase (AMP-forming)|aspartate-tRNAAsn ligase activity http://purl.obolibrary.org/obo/GO_0050560 GO:0050576 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050576 GO:0050577 biolink:MolecularActivity GDP-L-fucose synthase activity Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+. Reactome:R-HSA-6787642|RHEA:18885|MetaCyc:1.1.1.271-RXN|EC:1.1.1.271 go-plus.json GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)|GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity|GDP-fucose synthetase activity http://purl.obolibrary.org/obo/GO_0050577 GO:0050574 biolink:MolecularActivity 2-(R)-hydroxypropyl-CoM dehydrogenase activity Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH. UM-BBD_reactionID:r0852|RHEA:13249|KEGG_REACTION:R05689|MetaCyc:1.1.1.268-RXN|EC:1.1.1.268 go-plus.json 2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050574 GO:0050575 biolink:MolecularActivity 2-(S)-hydroxypropyl-CoM dehydrogenase activity Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH. UM-BBD_reactionID:r0853|MetaCyc:1.1.1.269-RXN|RHEA:21052|KEGG_REACTION:R05690|EC:1.1.1.269 go-plus.json 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050575 CHEBI:52489 biolink:ChemicalSubstance cobalt-precorrin-5B go-plus.json http://purl.obolibrary.org/obo/CHEBI_52489 GO:0050578 biolink:MolecularActivity (R)-2-hydroxyacid dehydrogenase activity Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+. RHEA:35735|MetaCyc:1.1.1.272-RXN|EC:1.1.1.272 go-plus.json (R)-sulfolactate:NAD(P)+ oxidoreductase activity|L-sulfolactate dehydrogenase activity|(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity|(R)-sulfolactate:NAD(P)(+) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050578 GO:0050579 biolink:MolecularActivity vellosimine dehydrogenase activity Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine. KEGG_REACTION:R05827|RHEA:20029|MetaCyc:1.1.1.273-RXN|EC:1.1.1.273 go-plus.json 10-deoxysarpagine:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050579 CL:0000237 biolink:Cell keratinizing barrier epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000237 CL:0000239 biolink:Cell brush border epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0000239 CL:0000232 biolink:Cell erythrocyte A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. go-plus.json red blood cell|RBC http://purl.obolibrary.org/obo/CL_0000232 CL:0000233 biolink:Cell platelet A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. go-plus.json enucleate thrombocyte|anucleate thrombocyte|blood platelet http://purl.obolibrary.org/obo/CL_0000233 CL:0000234 biolink:Cell phagocyte Any cell capable of ingesting particulate matter via phagocytosis. go-plus.json http://purl.obolibrary.org/obo/CL_0000234 CL:0000235 biolink:Cell macrophage A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. go-plus.json histiocyte http://purl.obolibrary.org/obo/CL_0000235 CL:0000236 biolink:Cell B cell A lymphocyte of B lineage that is capable of B cell mediated immunity. go-plus.json B-cell|B-lymphocyte|B lymphocyte http://purl.obolibrary.org/obo/CL_0000236 CHEBI:52485 biolink:ChemicalSubstance isopimara-7,15-dienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_52485 chebi_ph7_3 CHEBI:52486 biolink:ChemicalSubstance dehydroabietadienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52486 chebi_ph7_3 CHEBI:52487 biolink:ChemicalSubstance dehydroabietadienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_52487 chebi_ph7_3 CHEBI:52488 biolink:ChemicalSubstance cobalt-precorrin-5A go-plus.json http://purl.obolibrary.org/obo/CHEBI_52488 GO:0050572 biolink:MolecularActivity L-idonate 5-dehydrogenase activity Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+. MetaCyc:1.1.1.264-RXN|EC:1.1.1.264 go-plus.json L-idonate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050572 GO:0050573 biolink:MolecularActivity dTDP-4-dehydro-6-deoxyglucose reductase activity Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH. KEGG_REACTION:R05687|RHEA:36583|MetaCyc:1.1.1.266-RXN|EC:1.1.1.266 go-plus.json dTDP-D-fucose:NADP+ oxidoreductase activity|dTDP-4-keto-6-deoxyglucose reductase activity http://purl.obolibrary.org/obo/GO_0050573 CHEBI:52482 biolink:ChemicalSubstance levopimaradienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52482 chebi_ph7_3 GO:0050570 biolink:MolecularActivity 4-hydroxythreonine-4-phosphate dehydrogenase activity Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+. RHEA:32275|MetaCyc:1.1.1.262-RXN|EC:1.1.1.262 go-plus.json L-threonine 4-phosphate dehydrogenase activity|4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity|PdxA|NAD(+)-dependent threonine 4-phosphate dehydrogenase activity|NAD+-dependent threonine 4-phosphate dehydrogenase activity|4-(phosphohydroxy)-L-threonine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050570 CHEBI:52483 biolink:ChemicalSubstance levopimaradienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_52483 chebi_ph7_3 CHEBI:52484 biolink:ChemicalSubstance isopimara-7,15-dienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52484 chebi_ph7_3 GO:0050571 biolink:MolecularActivity 1,5-anhydro-D-fructose reductase activity Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH. RHEA:20665|KEGG_REACTION:R05682|MetaCyc:1.1.1.263-RXN|EC:1.1.1.263 go-plus.json 1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity|AF reductase activity http://purl.obolibrary.org/obo/GO_0050571 GO:0098521 biolink:CellularComponent inhibitory neuromuscular junction The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0098521 GO:0050587 biolink:MolecularActivity chlorite O2-lyase activity Catalysis of the reaction: chloride + O(2) = chlorite. EC:1.13.11.49|MetaCyc:1.13.11.49-RXN|RHEA:21404|UM-BBD_reactionID:r0982|KEGG_REACTION:R05721 go-plus.json chloride:oxygen oxidoreductase activity|chlorite dismutase activity http://purl.obolibrary.org/obo/GO_0050587 GO:0001576 biolink:BiologicalProcess globoside biosynthetic process The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). go-plus.json globoside anabolism|globoside synthesis|globoside formation|globoside biosynthesis http://purl.obolibrary.org/obo/GO_0001576 GO:0098522 biolink:CellularComponent neuromuscular junction of skeletal muscle fiber A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0098522 GO:0050588 biolink:MolecularActivity apo-beta-carotenoid-14',13'-dioxygenase activity Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal. RHEA:26023|EC:1.13.11.67|MetaCyc:1.13.12.12-RXN|KEGG_REACTION:R08889 go-plus.json apo-b-carotenoid-14',13'-dioxygenase activity|8'-apo-beta-carotenol:O2 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050588 GO:0001577 biolink:MolecularActivity obsolete galectin OBSOLETE. A lectin that exhibits calcium independent binding of beta-galactoside sugars. go-plus.json galectin|S-type lectin http://purl.obolibrary.org/obo/GO_0001577 GO:0050585 biolink:MolecularActivity 4-hydroxymandelate synthase activity Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2. EC:1.13.11.46|MetaCyc:1.13.11.46-RXN|RHEA:21376 go-plus.json 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)|4-hydroxyphenylpyruvate dioxygenase II activity http://purl.obolibrary.org/obo/GO_0050585 GO:0001578 biolink:BiologicalProcess microtubule bundle formation A process that results in a parallel arrangement of microtubules. go-plus.json microtubule bundling http://purl.obolibrary.org/obo/GO_0001578 GO:0098520 biolink:CellularComponent excitatory neuromuscular junction The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0098520 GO:0050586 biolink:MolecularActivity 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO. EC:1.13.11.48|MetaCyc:1.13.11.48-RXN|KEGG_REACTION:R05720|RHEA:21572 go-plus.json 1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity|(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity|3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity http://purl.obolibrary.org/obo/GO_0050586 GO:0001579 biolink:BiologicalProcess medium-chain fatty acid transport The directed movement of medium-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. go-plus.json http://purl.obolibrary.org/obo/GO_0001579 GO:0001572 biolink:BiologicalProcess lactosylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. go-plus.json lactosylceramide anabolism|lactosylceramide biosynthesis|lactosylceramide synthesis|lactosylceramide formation http://purl.obolibrary.org/obo/GO_0001572 GO:0001573 biolink:BiologicalProcess ganglioside metabolic process The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues. go-plus.json ganglioside metabolism http://purl.obolibrary.org/obo/GO_0001573 GO:0001574 biolink:BiologicalProcess ganglioside biosynthetic process The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues. go-plus.json ganglioside biosynthesis|ganglioside anabolism|ganglioside synthesis|ganglioside formation http://purl.obolibrary.org/obo/GO_0001574 GO:0050589 biolink:MolecularActivity leucocyanidin oxygenase activity Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O. MetaCyc:RXN-602|EC:1.14.20.4 go-plus.json anthocyanidin synthase activity|leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity|leucoanthocyanidin hydroxylase|leucoanthocyanidin dioxygenase activity http://purl.obolibrary.org/obo/GO_0050589 GO:0001575 biolink:BiologicalProcess globoside metabolic process The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes. go-plus.json globoside metabolism http://purl.obolibrary.org/obo/GO_0001575 CL:0000205 biolink:Cell thermoreceptor cell A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. go-plus.json http://purl.obolibrary.org/obo/CL_0000205 GO:0001570 biolink:BiologicalProcess vasculogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. Wikipedia:Vasculogenesis go-plus.json vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001570 CL:0000206 biolink:Cell chemoreceptor cell A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. go-plus.json http://purl.obolibrary.org/obo/CL_0000206 GO:0001571 biolink:MolecularActivity non-tyrosine kinase fibroblast growth factor receptor activity Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity. go-plus.json non-tyrosine kinase FGFR activity|non-tyrosine kinase FGF receptor activity http://purl.obolibrary.org/obo/GO_0001571 CL:0000207 biolink:Cell olfactory receptor cell go-plus.json olfactory sensory neuron|Schultze's cell|olfactory receptor neuron|odorant receptor cell http://purl.obolibrary.org/obo/CL_0000207 CL:0000209 biolink:Cell taste receptor cell A cell type found in the spherical or ovoid clusters of receptor cells found mainly in the epithelium of the tongue and constituting the end organs of the sense of taste. go-plus.json taste bud cell http://purl.obolibrary.org/obo/CL_0000209 CL:0000200 biolink:Cell touch receptor cell go-plus.json http://purl.obolibrary.org/obo/CL_0000200 CL:0000202 biolink:Cell auditory hair cell A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. go-plus.json inner ear receptor cell|inner ear hair cell|auditory receptor cell|cochlear hair cell http://purl.obolibrary.org/obo/CL_0000202 CL:0000203 biolink:Cell gravity sensitive cell go-plus.json http://purl.obolibrary.org/obo/CL_0000203 GO:0098529 biolink:BiologicalProcess neuromuscular junction development, skeletal muscle fiber A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0098529 GO:0050580 biolink:MolecularActivity 2,5-didehydrogluconate reductase activity Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+. MetaCyc:1.1.1.274-RXN|EC:1.1.1.274|RHEA:23828 go-plus.json YqhE reductase|2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity|2,5-diketo-D-gluconate reductase activity http://purl.obolibrary.org/obo/GO_0050580 GO:0098527 biolink:CellularComponent neuromuscular junction of somatic muscle A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods. go-plus.json http://purl.obolibrary.org/obo/GO_0098527 GO:0098528 biolink:BiologicalProcess skeletal muscle fiber differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. go-plus.json http://purl.obolibrary.org/obo/GO_0098528 GO:0050583 biolink:MolecularActivity hydrogen dehydrogenase (NADP+) activity Catalysis of the reaction: NADP+ + H2 = NADPH + H+. EC:1.12.1.3|MetaCyc:1.12.1.3-RXN|RHEA:18637 go-plus.json NADP-linked hydrogenase activity|hydrogen:NADP+ oxidoreductase activity|NADP-reducing hydrogenase activity http://purl.obolibrary.org/obo/GO_0050583 GO:0098525 biolink:CellularComponent excitatory neuromuscular junction of somatic myotube A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0098525 GO:0050584 biolink:MolecularActivity linoleate 11-lipoxygenase activity Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate. RHEA:18993|EC:1.13.11.45|KEGG_REACTION:R05718|MetaCyc:1.13.11.45-RXN go-plus.json manganese lipoxygenase activity|linoleate dioxygenase activity|linoleate:oxygen 11S-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050584 GO:0098526 biolink:CellularComponent inhibitory neuromuscular junction of somatic myotube A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods. go-plus.json http://purl.obolibrary.org/obo/GO_0098526 GO:0098523 biolink:CellularComponent neuromuscular junction of myotube A neuromuscular junction in which the target muscle cell is a myotube. go-plus.json http://purl.obolibrary.org/obo/GO_0098523 GO:0050581 biolink:MolecularActivity D-mannitol oxidase activity Catalysis of the reaction: mannitol + O2 = mannose + H2O2. MetaCyc:1.1.3.40-RXN|EC:1.1.3.40|RHEA:18513 go-plus.json mannitol oxidase activity|D-arabitol oxidase activity|D-arabinitol oxidase activity|mannitol:oxygen oxidoreductase (cyclizing) http://purl.obolibrary.org/obo/GO_0050581 GO:0050582 biolink:MolecularActivity xylitol oxidase activity Catalysis of the reaction: xylitol + O2 = xylose + H2O2. MetaCyc:1.1.3.41-RXN|EC:1.1.3.41 go-plus.json xylitol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050582 GO:0098524 biolink:CellularComponent neuromuscular junction of somatic muscle myotube A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098524 GO:0050598 biolink:MolecularActivity taxane 13-alpha-hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol. RHEA:18949|KEGG_REACTION:R06308|MetaCyc:1.14.13.77-RXN|EC:1.14.14.106 go-plus.json taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)|taxane 13alpha-hydroxylase activity|taxane 13a-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050598 GO:0001587 biolink:MolecularActivity Gq/11-coupled serotonin receptor activity Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels. go-plus.json 5-HT2 receptor activity|serotonin receptor activity, coupled via Gq/11 http://purl.obolibrary.org/obo/GO_0001587 GO:0098532 biolink:BiologicalProcess histone H3-K27 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0098532 GO:0050599 biolink:MolecularActivity deacetoxycephalosporin-C synthase activity Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate. RHEA:20748|EC:1.14.20.1|KEGG_REACTION:R05301|MetaCyc:1.14.20.1-RXN go-plus.json expandase activity|penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)|penicillin N expandase activity|DAOCS activity|DAOC synthase activity|deacetoxycephalosporin C synthetase activity http://purl.obolibrary.org/obo/GO_0050599 GO:0001588 biolink:MolecularActivity dopamine neurotransmitter receptor activity, coupled via Gs Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity. go-plus.json dopamine D1 receptor activity|dopamine D5 receptor activity http://purl.obolibrary.org/obo/GO_0001588 GO:0098533 biolink:CellularComponent ATPase dependent transmembrane transport complex A transmembrane protein complex that functions in ATPase dependent active transport across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098533 GO:0098530 biolink:BiologicalProcess positive regulation of strand invasion Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. go-plus.json positive regulation of Rad51-mediated strand invasion|positive regulation of D-loop biosynthesis|positive regulation of D-loop formation http://purl.obolibrary.org/obo/GO_0098530 GO:0050596 biolink:MolecularActivity vinorine hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine. KEGG_REACTION:R05877|MetaCyc:1.14.13.75-RXN|RHEA:17257|EC:1.14.14.104 go-plus.json vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating) http://purl.obolibrary.org/obo/GO_0050596 GO:0001589 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001589 GO:0098531 biolink:MolecularActivity ligand-activated transcription factor activity A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors. go-plus.json transcription factor activity, direct ligand regulated sequence-specific DNA binding|direct ligand regulated sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0098531 GO:0050597 biolink:MolecularActivity taxane 10-beta-hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+). KEGG_REACTION:R06309|MetaCyc:1.14.13.76-RXN|RHEA:15241|EC:1.14.14.105 go-plus.json taxane 10b-hydroxylase activity|taxane 10beta-hydroxylase activity|taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)|5-alpha-taxadienol-10-beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050597 GO:0001583 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of salty taste The series of events required for a salty taste stimulus to be received and converted to a molecular signal. go-plus.json perception of salty taste, sensory transduction of chemical stimulus|salty taste detection|perception of salty taste, detection of chemical stimulus|sensory detection of chemical stimulus during perception of salty taste|sensory transduction of salty taste|sensory transduction of chemical stimulus during perception of salty taste|sensory detection of salty taste http://purl.obolibrary.org/obo/GO_0001583 GO:0001584 biolink:MolecularActivity obsolete rhodopsin-like receptor activity OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor. go-plus.json Class A G-protein coupled receptor|class A orphan receptor activity|Class A GPCR|Class A G protein coupled receptor|rhodopsin-like receptor activity http://purl.obolibrary.org/obo/GO_0001584 CHEBI:52469 biolink:ChemicalSubstance precorrin-1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_52469 GO:1902108 biolink:BiologicalProcess regulation of mitochondrial membrane permeability involved in apoptotic process Any regulation of mitochondrial membrane permeability that is involved in apoptotic process. go-plus.json regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|regulation of transport across mitochondrial membrane involved in apoptotic program|regulation of mitochondrial membrane permeability involved in apoptotic program|regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|regulation of mitochondrial membrane permeability involved in type I programmed cell death|regulation of mitochondrial membrane permeability involved in apoptotic cell death|regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|regulation of transport across mitochondrial membrane involved in type I programmed cell death|regulation of transport across mitochondrial membrane involved in apoptotic cell death|regulation of transport across mitochondrial membrane involved in apoptosis|regulation of transport across mitochondrial membrane involved in apoptotic process|regulation of mitochondrial membrane permeability involved in apoptosis|regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_1902108 GO:0001585 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001585 GO:1902109 biolink:BiologicalProcess negative regulation of mitochondrial membrane permeability involved in apoptotic process Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process. go-plus.json negative regulation of transport across mitochondrial membrane involved in apoptosis|negative regulation of mitochondrial membrane permeability involved in type I programmed cell death|negative regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|negative regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in signaling (initiator) caspase activity|negative regulation of mitochondrial membrane permeability involved in apoptotic cell death|negative regulation of mitochondrial membrane permeability involved in apoptosis|negative regulation of transport across mitochondrial membrane involved in type I programmed cell death|negative regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|negative regulation of transport across mitochondrial membrane involved in apoptotic process|negative regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|negative regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial membrane impermeability involved in apoptotic cell death|negative regulation of transport across mitochondrial membrane involved in apoptotic program|mitochondrial membrane impermeability involved in type I programmed cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|mitochondrial membrane impermeability involved in apoptosis|mitochondrial membrane impermeabilization involved in apoptotic process|mitochondrial membrane impermeability involved in apoptotic process|mitochondrial membrane impermeabilization involved in apoptosis|mitochondrial membrane impermeabilization involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in apoptotic programmed cell death|mitochondrial membrane impermeabilization involved in apoptotic programmed cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic program|mitochondrial membrane impermeabilization involved in apoptotic cell death|mitochondrial membrane impermeabilization involved in apoptotic program|mitochondrial membrane impermeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane impermeabilization involved in type I programmed cell death|mitochondrial membrane impermeability involved in apoptotic program|negative regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis http://purl.obolibrary.org/obo/GO_1902109 GO:0001586 biolink:MolecularActivity Gi/o-coupled serotonin receptor activity Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels. go-plus.json serotonin receptor activity, coupled via Gi/o|5-HT1 receptor activity http://purl.obolibrary.org/obo/GO_0001586 GO:1902106 biolink:BiologicalProcess negative regulation of leukocyte differentiation Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. go-plus.json inhibition of leukocyte differentiation|down-regulation of immune cell differentiation|negative regulation of immune cell differentiation|down regulation of leucocyte differentiation|downregulation of leucocyte differentiation|inhibition of immune cell differentiation|down regulation of leukocyte differentiation|downregulation of leukocyte differentiation|negative regulation of leucocyte differentiation|down-regulation of leucocyte differentiation|down regulation of immune cell differentiation|inhibition of leucocyte differentiation|downregulation of immune cell differentiation|down-regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902106 CL:0000215 biolink:Cell barrier cell A cell whose primary function is to prevent the transport of stuff across compartments. go-plus.json http://purl.obolibrary.org/obo/CL_0000215 GO:0001580 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of bitter taste The series of events required for a bitter taste stimulus to be received and converted to a molecular signal. go-plus.json sensory detection of bitter taste|sensory transduction of chemical stimulus during perception of bitter taste|sensory detection of chemical stimulus during perception of bitter taste|perception of bitter taste, sensory transduction of chemical stimulus|sensory transduction of bitter taste|bitter taste detection|perception of bitter taste, detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0001580 GO:1902107 biolink:BiologicalProcess positive regulation of leukocyte differentiation Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. go-plus.json activation of immune cell differentiation|positive regulation of immune cell differentiation|up-regulation of leukocyte differentiation|upregulation of leucocyte differentiation|up-regulation of immune cell differentiation|upregulation of leukocyte differentiation|up regulation of leucocyte differentiation|activation of leucocyte differentiation|positive regulation of leucocyte differentiation|upregulation of immune cell differentiation|up regulation of leukocyte differentiation|activation of leukocyte differentiation|up-regulation of leucocyte differentiation|up regulation of immune cell differentiation http://purl.obolibrary.org/obo/GO_1902107 CL:0000216 biolink:Cell Sertoli cell A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. go-plus.json http://purl.obolibrary.org/obo/CL_0000216 GO:0001581 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of sour taste The series of events required for a sour taste stimulus to be received and converted to a molecular signal. go-plus.json sensory detection of sour taste|sensory transduction of chemical stimulus during perception of sour taste|sensory transduction of sour taste|sensory detection of chemical stimulus during perception of sour taste|sour taste detection|perception of sour taste, sensory transduction of chemical stimulus|perception of sour taste, detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0001581 GO:1902104 biolink:BiologicalProcess positive regulation of metaphase/anaphase transition of meiotic cell cycle Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle. go-plus.json upregulation of metaphase/anaphase transition of meiotic cell cycle|activation of meiotic metaphase/anaphase transition|up-regulation of meiotic metaphase/anaphase transition|up regulation of metaphase/anaphase transition of meiotic cell cycle|activation of metaphase/anaphase transition of meiotic cell cycle|upregulation of meiotic metaphase/anaphase transition|up-regulation of metaphase/anaphase transition of meiotic cell cycle|up regulation of meiotic metaphase/anaphase transition|positive regulation of meiotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1902104 CL:0000217 biolink:Cell insulating cell go-plus.json http://purl.obolibrary.org/obo/CL_0000217 GO:1902105 biolink:BiologicalProcess regulation of leukocyte differentiation Any process that modulates the frequency, rate or extent of leukocyte differentiation. go-plus.json regulation of leucocyte differentiation|regulation of immune cell differentiation http://purl.obolibrary.org/obo/GO_1902105 CL:0000218 biolink:Cell myelinating Schwann cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. go-plus.json peripheral neuroglial cell|Schwann cell|neurilemmal cell http://purl.obolibrary.org/obo/CL_0000218 GO:0001582 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of sweet taste The series of events required for a sweet taste stimulus to be received and converted to a molecular signal. go-plus.json sensory transduction of sweet taste|sensory detection of chemical stimulus during perception of sweet taste|sensory detection of sweet taste|sensory transduction of chemical stimulus during perception of sweet taste|perception of sweet taste, sensory transduction of chemical stimulus|sweet taste detection|perception of sweet taste, detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0001582 GO:1902102 biolink:BiologicalProcess regulation of metaphase/anaphase transition of meiotic cell cycle Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle. go-plus.json regulation of meiotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1902102 CL:0000219 biolink:Cell motile cell A cell that moves by its own activities. go-plus.json http://purl.obolibrary.org/obo/CL_0000219 GO:1902103 biolink:BiologicalProcess negative regulation of metaphase/anaphase transition of meiotic cell cycle Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle. go-plus.json negative regulation of meiotic metaphase/anaphase transition|down-regulation of meiotic metaphase/anaphase transition|down regulation of metaphase/anaphase transition of meiotic cell cycle|downregulation of metaphase/anaphase transition of meiotic cell cycle|inhibition of meiotic metaphase/anaphase transition|down-regulation of metaphase/anaphase transition of meiotic cell cycle|down regulation of meiotic metaphase/anaphase transition|inhibition of metaphase/anaphase transition of meiotic cell cycle|downregulation of meiotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1902103 GO:1902100 biolink:BiologicalProcess negative regulation of metaphase/anaphase transition of cell cycle Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle. go-plus.json down-regulation of metaphase/anaphase transition of cell cycle|inhibition of metaphase/anaphase transition of cell cycle|down regulation of metaphase/anaphase transition of cell cycle|downregulation of metaphase/anaphase transition of cell cycle http://purl.obolibrary.org/obo/GO_1902100 GO:1902101 biolink:BiologicalProcess positive regulation of metaphase/anaphase transition of cell cycle Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle. go-plus.json up-regulation of metaphase/anaphase transition of cell cycle|upregulation of metaphase/anaphase transition of cell cycle|up regulation of metaphase/anaphase transition of cell cycle|activation of metaphase/anaphase transition of cell cycle http://purl.obolibrary.org/obo/GO_1902101 GO:1902110 biolink:BiologicalProcess positive regulation of mitochondrial membrane permeability involved in apoptotic process Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process. go-plus.json mitochondrial membrane permeabilization involved in type I programmed cell death|mitochondrial permeability transition involved in apoptotic program|mitochondrial membrane permeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in apoptotic program|mitochondrial membrane permeability transition involved in apoptotic cell death|mitochondrial membrane permeability transition involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in type I programmed cell death|mitochondrial permeability transition involved in apoptotic cell death|mitochondrial membrane permeabilization involved in apoptotic program|positive regulation of transport across mitochondrial membrane involved in apoptosis|mitochondrial permeability transition involved in signaling (initiator) caspase activity|mitochondrial permeability transition involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptotic process|positive regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|positive regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptotic program|positive regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in apoptotic cell death|mitochondrial permeability transition involved in apoptosis|mitochondrial permeability transition involved in apoptotic process|positive regulation of transport across mitochondrial membrane involved in type I programmed cell death|positive regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|mitochondrial permeability transition involved in apoptotic programmed cell death|mitochondrial membrane permeabilization involved in programmed cell death by apoptosis|mitochondrial membrane permeability transition involved in apoptotic process|mitochondrial membrane permeability transition involved in apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptotic program|mitochondrial membrane permeability transition involved in apoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial membrane permeability transition involved in programmed cell death by apoptosis|mitochondrial membrane permeabilization involved in apoptotic process|mitochondrial membrane permeabilization involved in apoptosis|mitochondrial membrane permeabilization involved in apoptotic programmed cell death|mitochondrial permeability transition involved in programmed cell death by apoptosis|mitochondrial membrane permeabilization involved in apoptotic cell death http://purl.obolibrary.org/obo/GO_1902110 CL:0000210 biolink:Cell photoreceptor cell A cell specialized to detect and transduce light. go-plus.json http://purl.obolibrary.org/obo/CL_0000210 CL:0000211 biolink:Cell electrically active cell A cell whose function is determined by the generation or the reception of an electric signal. go-plus.json http://purl.obolibrary.org/obo/CL_0000211 CL:0000212 biolink:Cell absorptive cell A cell that takes up and metabolizes substances. go-plus.json http://purl.obolibrary.org/obo/CL_0000212 CL:0000213 biolink:Cell lining cell A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. go-plus.json boundary cell http://purl.obolibrary.org/obo/CL_0000213 GO:0050590 biolink:MolecularActivity desacetoxyvindoline 4-hydroxylase activity Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2. KEGG_REACTION:R05857|MetaCyc:1.14.11.20-RXN|RHEA:18973|EC:1.14.11.20 go-plus.json desacetyoxyvindoline-17-hydroxylase activity|D17H activity|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)|desacetoxyvindoline-4-hydroxylase activity|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity|deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating) http://purl.obolibrary.org/obo/GO_0050590 CHEBI:52463 biolink:ChemicalSubstance fusicocca-2,10(14)-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_52463 chebi_ph7_3 GO:0050591 biolink:MolecularActivity quinine 3-monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+). KEGG_REACTION:R05727|RHEA:20149|MetaCyc:1.14.13.67-RXN|EC:1.14.14.55 go-plus.json nifedipine oxidase activity|quinine 3-hydroxylase activity|quinine,NADPH:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050591 CHEBI:52464 biolink:ChemicalSubstance jasmonate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_52464 GO:0098538 biolink:CellularComponent lumenal side of transport vesicle membrane The side (leaflet) of the transport vesicle membrane that faces the lumen. go-plus.json internal side of transport vesicle membrane http://purl.obolibrary.org/obo/GO_0098538 GO:0098539 biolink:CellularComponent cytoplasmic side of transport vesicle membrane The side (leaflet) of the transport vesicle membrane that faces the cytoplasm. go-plus.json external side of transport vesicle membrane http://purl.obolibrary.org/obo/GO_0098539 GO:0098536 biolink:CellularComponent deuterosome A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles. go-plus.json http://purl.obolibrary.org/obo/GO_0098536 GO:0050594 biolink:MolecularActivity tabersonine 16-hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+). KEGG_REACTION:R05855|MetaCyc:1.14.13.73-RXN|RHEA:14133|EC:1.14.14.103 go-plus.json tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating) http://purl.obolibrary.org/obo/GO_0050594 GO:0050595 biolink:MolecularActivity 7-deoxyloganin 7-hydroxylase activity Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O. RHEA:11452|MetaCyc:1.14.13.74-RXN|EC:1.14.13.74 go-plus.json 7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) http://purl.obolibrary.org/obo/GO_0050595 GO:0098537 biolink:CellularComponent obsolete lobed nucleus OBSOLETE. Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans. go-plus.json http://purl.obolibrary.org/obo/GO_0098537 GO:0050592 biolink:MolecularActivity 4-hydroxyphenylacetaldehyde oxime monooxygenase activity Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+). KEGG_REACTION:R05728|MetaCyc:1.14.13.68-RXN|RHEA:18401|EC:1.14.14.37 go-plus.json 4-hydroxybenzeneacetaldehyde oxime monooxygenase activity|cytochrome P450-II-dependent monooxygenase activity|NADPH-cytochrome P450 reductase (CYP71E1)|(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity|CYP71E1 activity|cytochrome P450II-dependent monooxygenase activity|4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050592 GO:0098534 biolink:BiologicalProcess centriole assembly A cellular process that results in the assembly of one or more centrioles. go-plus.json http://purl.obolibrary.org/obo/GO_0098534 CHEBI:52461 biolink:ChemicalSubstance elisabethatriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_52461 chebi_ph7_3 GO:0098535 biolink:BiologicalProcess de novo centriole assembly involved in multi-ciliated epithelial cell differentiation Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation. go-plus.json centriole amplification|multiciliation|deuterosomal basal body biogenesis|multiciliogenesis|deuterosome-mediated centriole biogenesis|de novo centriole assembly via deuterosome|deuterosome pathway|de novo centriole assembly http://purl.obolibrary.org/obo/GO_0098535 GO:0050593 biolink:MolecularActivity N-methylcoclaurine 3'-monooxygenase activity Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+). RHEA:16649|KEGG_REACTION:R05732|MetaCyc:1.14.13.71-RXN|EC:1.14.14.102 go-plus.json cytochrome P450 80B1 activity|(S)-N-methylcoclaurine 3'-hydroxylase activity|N-methylcoclaurine 3'-hydroxylase activity|(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating) http://purl.obolibrary.org/obo/GO_0050593 GO:0001554 biolink:BiologicalProcess luteolysis The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy. Wikipedia:Luteolysis go-plus.json http://purl.obolibrary.org/obo/GO_0001554 GO:0001555 biolink:BiologicalProcess oocyte growth The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. go-plus.json http://purl.obolibrary.org/obo/GO_0001555 GO:0001556 biolink:BiologicalProcess oocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. Wikipedia:Oocyte_maturation go-plus.json http://purl.obolibrary.org/obo/GO_0001556 GO:0001557 biolink:BiologicalProcess obsolete metabolic process resulting in cell growth OBSOLETE. The chemical reactions that occur in living organisms that result in an increase in the mass (size) of a cell. go-plus.json metabolic process resulting in cell growth http://purl.obolibrary.org/obo/GO_0001557 GO:0001550 biolink:BiologicalProcess ovarian cumulus expansion Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells. go-plus.json ovarian cumulus growth http://purl.obolibrary.org/obo/GO_0001550 GO:0001551 biolink:BiologicalProcess ovarian follicle endowment Association of oocytes with supporting epithelial granulosa cells to form primordial follicles. go-plus.json http://purl.obolibrary.org/obo/GO_0001551 GO:1902119 biolink:BiologicalProcess regulation of meiotic spindle elongation Any process that modulates the frequency, rate or extent of meiotic spindle elongation. go-plus.json regulation of spindle elongation during meiosis http://purl.obolibrary.org/obo/GO_1902119 GO:0001552 biolink:BiologicalProcess ovarian follicle atresia A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed. go-plus.json http://purl.obolibrary.org/obo/GO_0001552 GO:0001553 biolink:BiologicalProcess luteinization The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation. Wikipedia:Luteal_phase|Wikipedia:Luteinization go-plus.json luteal phase http://purl.obolibrary.org/obo/GO_0001553 GO:1902117 biolink:BiologicalProcess positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. go-plus.json up regulation of organelle assembly|upregulation of organelle assembly|activation of organelle assembly|up-regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902117 GO:1902118 biolink:MolecularActivity calcidiol binding Binding to calcidiol. go-plus.json 25OHD3 binding|25-hydroxyvitamin D3 binding|25(OH)D3 binding|25-hydroxycholecalciferol binding|calcifediol binding http://purl.obolibrary.org/obo/GO_1902118 GO:1902115 biolink:BiologicalProcess regulation of organelle assembly Any process that modulates the frequency, rate or extent of organelle assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1902115 GO:1902116 biolink:BiologicalProcess negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. go-plus.json down-regulation of organelle assembly|downregulation of organelle assembly|down regulation of organelle assembly|inhibition of organelle assembly http://purl.obolibrary.org/obo/GO_1902116 CHEBI:27499 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27499 GO:1902113 biolink:BiologicalProcess nucleotide phosphorylation involved in DNA repair Any nucleotide phosphorylation that is involved in DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_1902113 GO:1902114 biolink:BiologicalProcess D-valine metabolic process The chemical reactions and pathways involving D-valine. go-plus.json D-valine metabolism http://purl.obolibrary.org/obo/GO_1902114 CHEBI:27493 biolink:ChemicalSubstance juvenile hormone III go-plus.json http://purl.obolibrary.org/obo/CHEBI_27493 chebi_ph7_3 GO:1902111 biolink:BiologicalProcess response to diethyl maleate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902111 GO:1902112 biolink:BiologicalProcess cellular response to diethyl maleate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902112 GO:1902120 biolink:BiologicalProcess negative regulation of meiotic spindle elongation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation. go-plus.json downregulation of meiotic spindle elongation|inhibition of spindle elongation during meiosis|down regulation of meiotic spindle elongation|inhibition of meiotic spindle elongation|down regulation of spindle elongation during meiosis|downregulation of spindle elongation during meiosis|negative regulation of spindle elongation during meiosis|down-regulation of spindle elongation during meiosis|down-regulation of meiotic spindle elongation http://purl.obolibrary.org/obo/GO_1902120 GO:1902121 biolink:MolecularActivity lithocholic acid binding Binding to lithocholic acid. go-plus.json LCA binding http://purl.obolibrary.org/obo/GO_1902121 GO:0098509 biolink:BiologicalProcess sensory perception of humidity The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json hygrosensory perception http://purl.obolibrary.org/obo/GO_0098509 GO:0098507 biolink:BiologicalProcess polynucleotide 5' dephosphorylation The process of removing one or more phosphate groups from the 5' end of a polynucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0098507 GO:0098508 biolink:BiologicalProcess endothelial to hematopoietic transition The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0098508 GO:0098505 biolink:MolecularActivity G-rich strand telomeric DNA binding Binding to G-rich, single-stranded, telomere-associated DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0098505 GO:0098506 biolink:BiologicalProcess polynucleotide 3' dephosphorylation The process of removing one or more phosphate groups from the 3' end of a polynucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0098506 GO:0098503 biolink:BiologicalProcess obsolete DNA 3' dephosphorylation OBSOLETE. The process of removing a 3' phosphate group from a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0098503 GO:0001558 biolink:BiologicalProcess regulation of cell growth Any process that modulates the frequency, rate, extent or direction of cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0001558 GO:0001559 biolink:BiologicalProcess obsolete regulation of cell growth by detection of nuclear:cytoplasmic ratio OBSOLETE. Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. go-plus.json interpretation of nuclear:cytoplasmic ratio to regulate cell growth|regulation of cell growth by sensing of nuclear:cytoplasmic ratio|regulation of cell growth by nuclear:cytoplasmic ratio|detection of nuclear:cytoplasmic ratio to regulate cell growth http://purl.obolibrary.org/obo/GO_0001559 GO:0098504 biolink:BiologicalProcess obsolete DNA 3' dephosphorylation involved in DNA repair OBSOLETE. Any 3' DNA dephosphorylation that is involved in the process of DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0098504 CHEBI:52450 biolink:ChemicalSubstance 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52450 chebi_ph7_3 GO:0098501 biolink:BiologicalProcess polynucleotide dephosphorylation The process of removing one or more phosphate groups from a polynucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0098501 GO:0098502 biolink:BiologicalProcess DNA dephosphorylation The process of removing one or more phosphate groups from a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0098502 GO:0098510 biolink:BiologicalProcess sensory perception of high humidity The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json http://purl.obolibrary.org/obo/GO_0098510 GO:0001565 biolink:MolecularActivity phorbol ester receptor activity Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001565 CHEBI:52449 biolink:ChemicalSubstance 5-oxo-ETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_52449 GO:0098511 biolink:BiologicalProcess sensory perception of low humidity The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json http://purl.obolibrary.org/obo/GO_0098511 GO:0001566 biolink:MolecularActivity non-kinase phorbol ester receptor activity Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001566 GO:0001567 biolink:MolecularActivity cholesterol 25-hydroxylase activity Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O. EC:1.14.99.38|MetaCyc:1.14.99.38-RXN|RHEA:21104|KEGG_REACTION:R07218 go-plus.json cholesterol 25-monooxygenase activity|cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0001567 GO:0001568 biolink:BiologicalProcess blood vessel development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. go-plus.json http://purl.obolibrary.org/obo/GO_0001568 GO:0001561 biolink:BiologicalProcess fatty acid alpha-oxidation A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway. MetaCyc:PWY-2501 go-plus.json http://purl.obolibrary.org/obo/GO_0001561 GO:0001562 biolink:BiologicalProcess response to protozoan Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan. go-plus.json response to protozoa|resistance to pathogenic protozoa|response to protozoon http://purl.obolibrary.org/obo/GO_0001562 CHEBI:52447 biolink:ChemicalSubstance tetrahydrodictyopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52447 chebi_ph7_3 GO:0001563 biolink:BiologicalProcess detection of protozoan The series of events in which a stimulus from a protozoan is received and converted into a molecular signal. go-plus.json detection of protozoa|detection of protozoon|perception of protozoa http://purl.obolibrary.org/obo/GO_0001563 GO:0001564 biolink:BiologicalProcess obsolete resistance to pathogenic protozoa OBSOLETE. (Was not defined before being made obsolete). go-plus.json resistance to pathogenic protozoa http://purl.obolibrary.org/obo/GO_0001564 CHEBI:52448 biolink:ChemicalSubstance amino monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52448 GO:1902128 biolink:BiologicalProcess (-)-lariciresinol catabolic process The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol. go-plus.json (-)-lariciresinol degradation|(-)-lariciresinol breakdown|(-)-lariciresinol catabolism http://purl.obolibrary.org/obo/GO_1902128 GO:1902129 biolink:BiologicalProcess (-)-lariciresinol biosynthetic process The chemical reactions and pathways resulting in the formation of (-)-lariciresinol. go-plus.json (-)-lariciresinol biosynthesis|(-)-lariciresinol anabolism|(-)-lariciresinol synthesis|(-)-lariciresinol formation http://purl.obolibrary.org/obo/GO_1902129 GO:1902126 biolink:BiologicalProcess (+)-pinoresinol biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-pinoresinol. go-plus.json (+)-pinoresinol anabolism|(+)-pinoresinol synthesis|(+)-pinoresinol formation|(+)-pinoresinol biosynthesis http://purl.obolibrary.org/obo/GO_1902126 GO:1902127 biolink:BiologicalProcess (-)-lariciresinol metabolic process The chemical reactions and pathways involving (-)-lariciresinol. go-plus.json (-)-lariciresinol metabolism http://purl.obolibrary.org/obo/GO_1902127 GO:0001560 biolink:BiologicalProcess regulation of cell growth by extracellular stimulus Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. go-plus.json regulation of growth by exogenous stimulus|regulation of growth by exogenous stimuli|regulation of growth by external stimuli|regulation of cell growth by sensing of exogenous stimulus|regulation of growth by external signal|regulation of cell growth by detection of exogenous stimulus|regulation of growth by exogenous signal|interpretation of external signals that regulate cell growth|regulation of growth by external stimulus http://purl.obolibrary.org/obo/GO_0001560 GO:1902124 biolink:BiologicalProcess (+)-pinoresinol metabolic process The chemical reactions and pathways involving (+)-pinoresinol. go-plus.json (+)-pinoresinol metabolism http://purl.obolibrary.org/obo/GO_1902124 GO:1902125 biolink:BiologicalProcess (+)-pinoresinol catabolic process The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol. go-plus.json (+)-pinoresinol breakdown|(+)-pinoresinol catabolism|(+)-pinoresinol degradation http://purl.obolibrary.org/obo/GO_1902125 GO:1902122 biolink:MolecularActivity chenodeoxycholic acid binding Binding to chenodeoxycholic acid. go-plus.json CDCA binding http://purl.obolibrary.org/obo/GO_1902122 GO:1902123 biolink:BiologicalProcess (-)-pinoresinol catabolic process The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol. go-plus.json (-)-pinoresinol degradation|(-)-pinoresinol breakdown|(-)-pinoresinol catabolism http://purl.obolibrary.org/obo/GO_1902123 GO:1902131 biolink:BiologicalProcess (+)-lariciresinol catabolic process The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol. go-plus.json (+)-lariciresinol degradation|(+)-lariciresinol breakdown|(+)-lariciresinol catabolism http://purl.obolibrary.org/obo/GO_1902131 GO:1902132 biolink:BiologicalProcess (+)-lariciresinol biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-lariciresinol. go-plus.json (+)-lariciresinol biosynthesis|(+)-lariciresinol anabolism|(+)-lariciresinol synthesis|(+)-lariciresinol formation http://purl.obolibrary.org/obo/GO_1902132 GO:1902130 biolink:BiologicalProcess (+)-lariciresinol metabolic process The chemical reactions and pathways involving (+)-lariciresinol. go-plus.json (+)-lariciresinol metabolism http://purl.obolibrary.org/obo/GO_1902130 GO:0098518 biolink:MolecularActivity polynucleotide phosphatase activity Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0098518 CHEBI:52442 biolink:ChemicalSubstance 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52442 chebi_ph7_3 GO:0098519 biolink:MolecularActivity nucleotide phosphatase activity, acting on free nucleotides Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate. go-plus.json nucleotide phosphatase activity http://purl.obolibrary.org/obo/GO_0098519 GO:0098516 biolink:BiologicalProcess detection of high humidity The series of events in which high humidity is detected and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0098516 CHEBI:52443 biolink:ChemicalSubstance 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52443 GO:0098517 biolink:BiologicalProcess detection of low humidity The series of events in which low humidity is detected and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0098517 GO:0098514 biolink:BiologicalProcess detection of high humidity stimulus involved in sensory perception The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity. go-plus.json http://purl.obolibrary.org/obo/GO_0098514 GO:0001569 biolink:BiologicalProcess branching involved in blood vessel morphogenesis The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. go-plus.json patterning of blood vessels http://purl.obolibrary.org/obo/GO_0001569 GO:0098515 biolink:BiologicalProcess detection of low humidity stimulus involved in sensory perception The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity. go-plus.json http://purl.obolibrary.org/obo/GO_0098515 GO:0098512 biolink:BiologicalProcess detection of humidity stimulus involved in sensory perception The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity. go-plus.json http://purl.obolibrary.org/obo/GO_0098512 GO:0098513 biolink:BiologicalProcess detection of humidity The series of events in which a humidity stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0098513 CHEBI:52440 biolink:ChemicalSubstance cephalosporin carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_52440 CHEBI:76409 biolink:ChemicalSubstance (2E,11Z,14Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76409 chebi_ph7_3 CHEBI:76408 biolink:ChemicalSubstance (3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76408 chebi_ph7_3 OPL:0000033 biolink:OntologyClass trypomastigote stage A parasite lifecycle stage of trypanosomes. In trypomastigote stage, the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane. go-plus.json http://purl.obolibrary.org/obo/OPL_0000033 PO:0009066 biolink:OntologyClass anther A collective plant organ structure (PO:0025007) that is the pollen-bearing part of a stamen (PO:0009029). go-plus.json 半葯,花粉のう (Japanese, exact)|Poaceae anther (narrow)|antera (Spanish, exact)|Zea anther (narrow) http://purl.obolibrary.org/obo/PO_0009066 PO:0009060 biolink:OntologyClass calyx A collective phyllome structure (PO:0025023) that is composed of one or more sepals (PO:0009031), and comprises the outer whorl of non-reproductive floral organs (PO:0025395). go-plus.json cálix (Spanish, exact)|calyces (exact, plural)|がく (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009060 PO:0009061 biolink:OntologyClass androecium A collective phyllome structure (PO:0025023) composed all of the stamens (PO:0009029) in a flower (PO:0009046). go-plus.json androecium of upper floret of pedicellate spikelet of tassel (exact)|androecium column (narrow)|androecia (exact, plural)|Poaceae androecium (narrow)|androecium of tassel floret (exact)|androecium of lower floret of sessile spikelet of ear (narrow)|androecium of upper floret of sessile spikelet of ear (narrow)|雄蕊群 (Japanese, exact)|androecium of lower floret of pedicellate spikelet of ear (narrow)|androecium of upper floret of pedicellate spikelet of ear (narrow)|androecium of upper floret of sessile spikelet of tassel (narrow)|androecio (Spanish, exact)|Zea androecium (narrow)|androecium of ear floret (narrow)|androecium of lower floret of sessile spikelet of tassel (narrow) http://purl.obolibrary.org/obo/PO_0009061 PO:0009062 biolink:OntologyClass gynoecium A collective phyllome structure (PO:0025023) composed all of the carpels (PO:0009030) in a flower (PO:0009046). go-plus.json apocarpous gynoecium (narrow)|Zea gynoecium (narrow)|ginoecio (Spanish, exact)|gynoecia (exact, plural)|gynoecium of tassel floret (narrow)|pistil (broad)|雌蕊群 (Japanese, exact)|gynoecium of lower floret of sessile spikelet of ear (narrow)|gynoecium of upper floret of sessile spikelet of ear (narrow)|gynoecium of upper floret of pedicellate spikelet of tassel (narrow)|gynoecium of lower floret of pedicellate spikelet of tassel (narrow)|gynoecium of lower floret of pedicellate spikelet of ear (narrow)|gynoecium of upper floret of pedicellate spikelet of ear (narrow)|Poaceae gynoecium (narrow)|syncarpous gynoecium (narrow)|gynoecium of upper floret of sessile spikelet of tassel (narrow)|gynaecium (exact)|gynoecium of lower floret of sessile spikelet of tassel (narrow)|gynoecium of ear floret (narrow) http://purl.obolibrary.org/obo/PO_0009062 PO:0009067 biolink:OntologyClass filament A stalk (PO:0025066) that is part of a stamen (PO:0009029). go-plus.json filamento (Spanish, exact)|Zea filament (narrow)|花糸 (Japanese, exact)|Poaceae filament (narrow) http://purl.obolibrary.org/obo/PO_0009067 CHEBI:76416 biolink:ChemicalSubstance (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76416 chebi_ph7_3 CHEBI:76417 biolink:ChemicalSubstance (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76417 chebi_ph7_3 CHEBI:76414 biolink:ChemicalSubstance propellant go-plus.json http://purl.obolibrary.org/obo/CHEBI_76414 CHEBI:76415 biolink:ChemicalSubstance (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76415 chebi_ph7_3 CHEBI:76418 biolink:ChemicalSubstance (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76418 chebi_ph7_3 CHEBI:76419 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z)-3-oxohexacosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76419 chebi_ph7_3 OPL:0000022 biolink:OntologyClass bloodstream trypomastigote stage A trypomastigote stage where trypmastigote form of parasites are found in mammalian host blood stream. go-plus.json http://purl.obolibrary.org/obo/OPL_0000022 PO:0009055 biolink:OntologyClass bract A phyllome that subtends a reproductive structure. go-plus.json 苞葉 (Japanese, exact)|scale (narrow)|bractlet (related)|bráctea (Spanish, exact)|hypsophyll (related)|bracteole (related) http://purl.obolibrary.org/obo/PO_0009055 CHEBI:76412 biolink:ChemicalSubstance (2E,8Z,11Z,14Z)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76412 chebi_ph7_3 CHEBI:76413 biolink:ChemicalSubstance greenhouse gas go-plus.json http://purl.obolibrary.org/obo/CHEBI_76413 PO:0009058 biolink:OntologyClass perianth A collective phyllome structure (PO:0025023) that includes as parts the corolla (PO:0009059) and/or the calyx (PO:0009060); or one or more tepals (PO:0009033). go-plus.json calyptra perianth (narrow)|connate perianth (related)|花蓋、花被 (Japanese, exact)|perianto (Spanish, exact)|adnate perianth (narrow) http://purl.obolibrary.org/obo/PO_0009058 CHEBI:76410 biolink:ChemicalSubstance (11Z,14Z)-icosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76410 chebi_ph7_3 PO:0009059 biolink:OntologyClass corolla A collective phyllome structure (PO:0025023) that is composed of one or more petals (PO:0009032), comprising the inner whorl of non-reproductive floral organs (PO:0025395) and surrounds the androecium (PO:0009061) and the gynoecium (PO:0009062). go-plus.json corollas (exact, plural)|corola (Spanish, exact)|corollae (exact, plural)|花冠 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009059 CHEBI:76411 biolink:ChemicalSubstance (3R,8Z,11Z,14Z)-3-hydroxyicosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76411 chebi_ph7_3 CHEBI:76427 biolink:ChemicalSubstance trans-2-dodecenedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76427 CHEBI:76428 biolink:ChemicalSubstance (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76428 chebi_ph7_3 CHEBI:76425 biolink:ChemicalSubstance (S)-3-hydroxyoctanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76425 CHEBI:76426 biolink:ChemicalSubstance 3-oxooctanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76426 CHEBI:76429 biolink:ChemicalSubstance (S)-3-hydroxydodecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76429 PO:0009049 biolink:OntologyClass inflorescence A reproductive shoot system (PO:0025082) that has as parts all of the shoot axes (PO:0025029) and flowers (PO:0009046; must have two or more) distal to the most distal leaf (PO:0009025). go-plus.json 花序 (Japanese, exact)|Triticeae spike (narrow)|inflorescencia (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009049 CHEBI:76420 biolink:ChemicalSubstance (3R,11Z,14Z,17Z,20Z)-3-hydroxyhexacosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76420 chebi_ph7_3 CHEBI:76423 biolink:ChemicalSubstance trans-2-octenedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76423 PO:0009046 biolink:OntologyClass flower A determinate reproductive shoot system (PO:0025082) that has as part at least one carpel (PO:0009030) or at least one stamen (PO:0009029) and does not contain any other determinate shoot system (PO:0009006) as a part. go-plus.json basal flower (narrow)|monoclinous flower (narrow)|Asteraceae floret (narrow)|花 (Japanese, exact)|hermaphrodite flower (narrow)|double flower (narrow)|flor (Spanish, exact)|perfect flower (narrow)|floret (related) http://purl.obolibrary.org/obo/PO_0009046 CHEBI:76424 biolink:ChemicalSubstance quercetin O-glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_76424 CHEBI:76421 biolink:ChemicalSubstance (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76421 chebi_ph7_3 CHEBI:76422 biolink:ChemicalSubstance (3R,13Z,16Z,19Z,22Z)-3-hydroxyoctacosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76422 chebi_ph7_3 CHEBI:76438 biolink:ChemicalSubstance (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76438 chebi_ph7_3 CHEBI:76439 biolink:ChemicalSubstance 3-oxododecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76439 UBERON:0010190 biolink:AnatomicalEntity pair of dorsal aortae the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation go-plus.json paired dorsal aortae http://purl.obolibrary.org/obo/UBERON_0010190 CHEBI:76436 biolink:ChemicalSubstance (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76436 chebi_ph7_3 CHEBI:76437 biolink:ChemicalSubstance (3R,21Z,24Z,27Z,30Z)-3-hydroxyhexatriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76437 chebi_ph7_3 UBERON:0010191 biolink:AnatomicalEntity aortic system go-plus.json http://purl.obolibrary.org/obo/UBERON_0010191 UBERON:0010192 biolink:AnatomicalEntity genital artery One of the laterally paired arteries that supply the gonads. go-plus.json gonadal artery http://purl.obolibrary.org/obo/UBERON_0010192 UBERON:0010199 biolink:AnatomicalEntity bona-fide anatomical boundary An anatomical boundary that corresponds to some physical discontinuity. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010199 PO:0009030 biolink:OntologyClass carpel A megasporophyll, almost always at the center of a flower, its margins more or less fused together or with other carpels to enclose the ovule(s). go-plus.json 心皮 (Japanese, exact)|pistil (broad)|Zea carpel (narrow)|carpelo (Spanish, exact)|Poaceae carpel (narrow) http://purl.obolibrary.org/obo/PO_0009030 OPL:0000006 biolink:OntologyClass metacyclic promastigote stage A promastigote stage of some kinetoplastids. go-plus.json http://purl.obolibrary.org/obo/OPL_0000006 PO:0009031 biolink:OntologyClass sepal A phyllome (PO:0006001) that is usually green, and is part of the calyx (PO:0009060). go-plus.json がく片 (Japanese, exact)|sépalo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009031 PO:0009032 biolink:OntologyClass petal A phyllome (PO:0006001) that is part of the corolla (PO:0009059), and is usually colored (not green). go-plus.json pétalo (Spanish, exact)|花弁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009032 CHEBI:76430 biolink:ChemicalSubstance (3R,15Z,18Z,21Z,24Z)-3-hydroxytriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76430 chebi_ph7_3 CHEBI:76431 biolink:ChemicalSubstance (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76431 chebi_ph7_3 CHEBI:76434 biolink:ChemicalSubstance (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76434 chebi_ph7_3 CHEBI:76435 biolink:ChemicalSubstance (3R,19Z,22Z,25Z,28Z)-3-hydroxytetratriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76435 chebi_ph7_3 PO:0009035 biolink:OntologyClass nectary A portion of secretory tissue (PO:0005656) which is a multicellular glandular structure secreting a liquid containing organic substances, including sugars. go-plus.json 蜜腺 (Japanese, exact)|nectario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009035 CHEBI:76432 biolink:ChemicalSubstance (3R,17Z,20Z,23Z,26Z)-3-hydroxydotriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76432 chebi_ph7_3 GO:1990673 biolink:CellularComponent intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic component of endoplasmic reticulum-Golgi intermediate compartment membrane http://purl.obolibrary.org/obo/GO_1990673 CHEBI:76449 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76449 GO:0050500 biolink:MolecularActivity 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate. RHEA:20285|MetaCyc:2.4.1.211-RXN|EC:2.4.1.211 go-plus.json beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity|beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity|beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0050500 GO:1990674 biolink:CellularComponent Golgi cis cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex. go-plus.json cis-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990674 GO:1990675 biolink:CellularComponent Golgi medial cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex. go-plus.json medial-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990675 CHEBI:76447 biolink:ChemicalSubstance (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76447 CHEBI:76448 biolink:ChemicalSubstance (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76448 GO:1990676 biolink:CellularComponent Golgi trans cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex. go-plus.json trans-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990676 GO:0050503 biolink:MolecularActivity trehalose 6-phosphate phosphorylase activity Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate. RHEA:20864|MetaCyc:2.4.1.216-RXN|EC:2.4.1.216 go-plus.json trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050503 GO:0050504 biolink:MolecularActivity mannosyl-3-phosphoglycerate synthase activity Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+). RHEA:13537|KEGG_REACTION:R05768|MetaCyc:2.4.1.217-RXN|EC:2.4.1.217 go-plus.json GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity|MPG synthase activity http://purl.obolibrary.org/obo/GO_0050504 GO:1990670 biolink:BiologicalProcess vesicle fusion with Golgi cis cisterna membrane The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_1990670 GO:0050501 biolink:MolecularActivity hyaluronan synthase activity Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP. RHEA:12528|Reactome:R-HSA-2160851|MetaCyc:2.4.1.212-RXN|EC:2.4.1.212 go-plus.json seHAS|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|spHAS|HAS activity http://purl.obolibrary.org/obo/GO_0050501 GO:1990671 biolink:BiologicalProcess vesicle fusion with Golgi medial cisterna membrane The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_1990671 GO:1990672 biolink:BiologicalProcess medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport. go-plus.json http://purl.obolibrary.org/obo/GO_1990672 GO:0050502 biolink:MolecularActivity cis-zeatin O-beta-D-glucosyltransferase activity Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP. RHEA:20681|EC:2.4.1.215|KEGG_REACTION:R07260|MetaCyc:RXN-4735 go-plus.json UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity|cis-zeatin O-b-D-glucosyltransferase activity|UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050502 GO:0050507 biolink:MolecularActivity indoxyl-UDPG glucosyltransferase activity Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP. RHEA:12004|KEGG_REACTION:R06048|MetaCyc:2.4.1.220-RXN|EC:2.4.1.220 go-plus.json indoxyl-UDPG-glucosyltransferase activity|UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050507 GO:0050508 biolink:MolecularActivity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP. Reactome:R-HSA-3656254|Reactome:R-HSA-3656261|MetaCyc:2.4.1.224-RXN|Reactome:R-HSA-9036290|RHEA:16213|EC:2.4.1.224|Reactome:R-HSA-2022851|Reactome:R-HSA-2022919|Reactome:R-HSA-9036283 go-plus.json glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase II activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0050508 OPL:0000076 biolink:OntologyClass procyclic trypomastigote stage A trypomastigote stage where trypomastigote form of parasites are in dividing form. This stage occurs in fly vector. go-plus.json http://purl.obolibrary.org/obo/OPL_0000076 GO:0050505 biolink:MolecularActivity hydroquinone glucosyltransferase activity Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP. MetaCyc:2.4.1.218-RXN|KEGG_REACTION:R05769|EC:2.4.1.218|RHEA:12560 go-plus.json UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity|arbutin synthase activity|UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity|hydroquinone:O-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050505 GO:0050506 biolink:MolecularActivity vomilenine glucosyltransferase activity Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP. MetaCyc:2.4.1.219-RXN|EC:2.4.1.219|KEGG_REACTION:R05882|RHEA:19385 go-plus.json UDPG:vomilenine 21-beta-D-glucosyltransferase activity|UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity|UDPG:vomilenine 21beta-D-glucosyltransferase activity|vomilenine-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050506 GO:0050509 biolink:MolecularActivity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP. MetaCyc:2.4.1.225-RXN|Reactome:R-HSA-2076392|EC:2.4.1.225|Reactome:R-HSA-2022856|Reactome:R-HSA-9036289|Reactome:R-HSA-9036285|RHEA:20908|Reactome:R-HSA-3656267|Reactome:R-HSA-3656257 go-plus.json N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity|heparan glucuronyltransferase II activity|N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity|UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0050509 CL:0000287 biolink:Cell eye photoreceptor cell go-plus.json http://purl.obolibrary.org/obo/CL_0000287 CHEBI:76441 biolink:ChemicalSubstance (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76441 chebi_ph7_3 CHEBI:76442 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76442 chebi_ph7_3 CHEBI:76440 biolink:ChemicalSubstance (3R,23Z,26Z,29Z,32Z)-3-hydroxyoctatriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76440 chebi_ph7_3 GO:1990677 biolink:CellularComponent mitochondrial inner membrane assembly complex A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion. go-plus.json mitochondrion inner membrane assembly complex|INAC complex|inner membrane assembly complex http://purl.obolibrary.org/obo/GO_1990677 CHEBI:76445 biolink:ChemicalSubstance 3-oxodecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76445 GO:1990678 biolink:BiologicalProcess histone H4-K16 deacetylation The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_1990678 CHEBI:76446 biolink:ChemicalSubstance (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76446 GO:1990679 biolink:BiologicalProcess histone H4-K12 deacetylation The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_1990679 CHEBI:76443 biolink:ChemicalSubstance trans-2-decenedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76443 CHEBI:76444 biolink:ChemicalSubstance (S)-3-hydroxydecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76444 GO:0050510 biolink:MolecularActivity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP. MetaCyc:2.4.1.226-RXN|Reactome:R-HSA-3595178|Reactome:R-HSA-9632034|EC:2.4.1.226|Reactome:R-HSA-1971491 go-plus.json chondroitin glucuronyltransferase II activity|alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity|N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0050510 GO:1990684 biolink:CellularComponent protein-lipid-RNA complex A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other. go-plus.json miRNA-lipoprotein complex http://purl.obolibrary.org/obo/GO_1990684 GO:0050511 biolink:MolecularActivity undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP. RHEA:23192|MetaCyc:RXN-8976|EC:2.4.1.227 go-plus.json undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity|MurG transferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity|undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity http://purl.obolibrary.org/obo/GO_0050511 GO:1990685 biolink:CellularComponent HDL-containing protein-lipid-RNA complex A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other. go-plus.json http://purl.obolibrary.org/obo/GO_1990685 GO:1990686 biolink:CellularComponent LDL-containing protein-lipid-RNA complex A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other. go-plus.json http://purl.obolibrary.org/obo/GO_1990686 CHEBI:76458 biolink:ChemicalSubstance (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76458 chebi_ph7_3 CHEBI:76459 biolink:ChemicalSubstance (R)-3-hydroxybehenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76459 GO:1990687 biolink:BiologicalProcess endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport. go-plus.json ER-derived vesicle fusion with ERGIC membrane|ER-derived vesicle fusion with ER-Golgi intermediate compartment membrane http://purl.obolibrary.org/obo/GO_1990687 GO:1990680 biolink:BiologicalProcess response to melanocyte-stimulating hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates. go-plus.json response to MSH http://purl.obolibrary.org/obo/GO_1990680 GO:0050514 biolink:MolecularActivity homospermidine synthase (spermidine-specific) activity Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine. MetaCyc:2.5.1.45-RXN|EC:2.5.1.45|RHEA:11236 go-plus.json spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming) http://purl.obolibrary.org/obo/GO_0050514 GO:0050515 biolink:MolecularActivity 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+). MetaCyc:2.7.1.148-RXN|KEGG_REACTION:R05634|RHEA:18437|EC:2.7.1.148 go-plus.json 4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity|CMK activity|ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity|CDP-ME kinase activity http://purl.obolibrary.org/obo/GO_0050515 GO:1990681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990681 GO:0050512 biolink:MolecularActivity lactosylceramide 4-alpha-galactosyltransferase activity Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP. RHEA:11924|MetaCyc:2.4.1.228-RXN|EC:2.4.1.228 go-plus.json UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity|histo-blood group Pk UDP-galactose|lactosylceramide 4-a-galactosyltransferase activity|histo-blood group P(k) UDP-galactose activity|Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity|Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity|globotriaosylceramide/CD77 synthase activity http://purl.obolibrary.org/obo/GO_0050512 GO:1990682 biolink:CellularComponent CSF1-CSF1R complex A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand. go-plus.json CSF1:C-FMS complex|macrophage colony-stimulating factor:receptor complex|M-CSF:C-FMS complex|M-CSF:FMS complex|M-CSF:CSF1R complex http://purl.obolibrary.org/obo/GO_1990682 GO:1990683 biolink:BiologicalProcess DNA double-strand break attachment to nuclear envelope A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs. go-plus.json http://purl.obolibrary.org/obo/GO_1990683 GO:0050513 biolink:MolecularActivity glycoprotein 2-beta-D-xylosyltransferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP. EC:2.4.2.38|RHEA:10612|KEGG_REACTION:R06016|MetaCyc:2.4.2.38-RXN go-plus.json glycoprotein 2-b-D-xylosyltransferase activity|1,2-beta-xylosyltransferase activity|beta-1,2-xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0050513 GO:0050518 biolink:MolecularActivity 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate. EC:2.7.7.60|MetaCyc:2.7.7.60-RXN|RHEA:13429|KEGG_REACTION:R05633 go-plus.json MEP cytidylyltransferase activity|MCT activity|CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity|4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity http://purl.obolibrary.org/obo/GO_0050518 GO:0050519 biolink:MolecularActivity holo-citrate lyase synthase activity Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase. EC:2.7.7.61|MetaCyc:2.7.7.61-RXN|RHEA:16333 go-plus.json 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity|2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity|CitX|holo-ACP synthase activity http://purl.obolibrary.org/obo/GO_0050519 GO:0050516 biolink:MolecularActivity obsolete inositol polyphosphate multikinase activity OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate, and ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. EC:2.7.1.151|MetaCyc:2.7.1.151-RXN go-plus.json IP3/IP4 dual-specificity 6-/3-kinase activity|inositol-polyphosphate multikinase activity|AtIpk2beta|IP3/IP4 6-/3-kinase activity|ArgRIII|AtIpk2-alpha activity|IpmK|inositol polyphosphate multikinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|IpK2 activity|AtIpk2-beta activity|AtIpk2alpha|inositol polyphosphate 6-/3-/5-kinase activity http://purl.obolibrary.org/obo/GO_0050516 GO:0050517 biolink:MolecularActivity obsolete inositol hexakisphosphate kinase activity OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate, and ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown). EC:2.7.4.21|MetaCyc:2.7.1.152-RXN go-plus.json inositol-hexakisphosphate kinase activity|ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity|ATP:1D-myo-inositol-hexakisphosphate phosphotransferase activity|inositol hexakisphosphate kinase activity http://purl.obolibrary.org/obo/GO_0050517 CL:0000295 biolink:Cell somatotropin secreting cell A peptide hormone secreting cell that produces growth hormone, somatotropin. go-plus.json somatotrophin secreting cell|growth hormone secreting cell http://purl.obolibrary.org/obo/CL_0000295 CHEBI:76452 biolink:ChemicalSubstance dialuric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76452 CHEBI:76453 biolink:ChemicalSubstance (R)-3-hydroxyicosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76453 CHEBI:76450 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76450 GO:1990688 biolink:BiologicalProcess Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. go-plus.json Golgi vesicle fusion with ER-Golgi intermediate compartment membrane|Golgi vesicle fusion with ERGIC membrane http://purl.obolibrary.org/obo/GO_1990688 CHEBI:76456 biolink:ChemicalSubstance (2E,11Z,14Z,17Z)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76456 chebi_ph7_3 GO:1990689 biolink:BiologicalProcess endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport. go-plus.json ERGIC-derived vesicle fusion with cis-Golgi cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with cis-Golgi cisterna membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with cis-Golgi cisterna membrane|ERGIC-derived vesicle fusion with Golgi cis cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with Golgi cis cisterna membrane http://purl.obolibrary.org/obo/GO_1990689 CHEBI:76457 biolink:ChemicalSubstance (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76457 chebi_ph7_3 CHEBI:76454 biolink:ChemicalSubstance (R)-3-hydroxystearoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76454 CHEBI:76455 biolink:ChemicalSubstance (3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76455 chebi_ph7_3 GO:1990695 biolink:CellularComponent intrinsic component of Golgi trans cisterna membrane The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic component of trans-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990695 GO:0050521 biolink:MolecularActivity alpha-glucan, water dikinase activity Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate. MetaCyc:2.7.9.4-RXN|EC:2.7.9.4|RHEA:11668 go-plus.json starch-related R1 protein activity|alpha-glucan,water dikinase activity|a-glucan, water dikinase activity|ATP:alpha-glucan, water phosphotransferase activity|GWD http://purl.obolibrary.org/obo/GO_0050521 GO:1990696 biolink:CellularComponent USH2 complex A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7. go-plus.json USH2 quaternary protein complex http://purl.obolibrary.org/obo/GO_1990696 GO:0050522 biolink:MolecularActivity oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP. EC:1.20.98.- go-plus.json http://purl.obolibrary.org/obo/GO_0050522 GO:1990697 biolink:BiologicalProcess protein depalmitoleylation The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_1990697 CHEBI:76469 biolink:ChemicalSubstance (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76469 chebi_ph7_3 GO:1990698 biolink:MolecularActivity palmitoleoyltransferase activity Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990698 GO:0050520 biolink:MolecularActivity phosphatidylcholine synthase activity Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+). RHEA:14597|KEGG_REACTION:R05794|EC:2.7.8.24|MetaCyc:2.7.8.24-RXN go-plus.json CDP-diacylglycerol:choline O-phosphatidyltransferase activity|CDP-diglyceride-choline O-phosphatidyltransferase activity|CDPdiglyceride-choline O-phosphatidyltransferase activity|PC synthase activity http://purl.obolibrary.org/obo/GO_0050520 GO:1990691 biolink:BiologicalProcess cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport. go-plus.json cis-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990691 GO:0050525 biolink:MolecularActivity cutinase activity Catalysis of the reaction: cutin + H2O = cutin monomers. EC:3.1.1.74|MetaCyc:3.1.1.74-RXN go-plus.json cutin hydrolase activity http://purl.obolibrary.org/obo/GO_0050525 GO:0050526 biolink:MolecularActivity poly(3-hydroxybutyrate) depolymerase activity Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5. EC:3.1.1.75|RHEA:11248|MetaCyc:3.1.1.75-RXN go-plus.json PHB depolymerase activity|poly((R)-hydroxyalkanoic acid) depolymerase activity|poly(HA(SCL)) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|poly[(R)-3-hydroxybutyrate] hydrolase activity|poly(HASCL) depolymerase activity|poly(3HB) depolymerase activity|poly(HA) depolymerase activity http://purl.obolibrary.org/obo/GO_0050526 GO:1990692 biolink:BiologicalProcess trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. go-plus.json trans-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990692 GO:0050523 biolink:MolecularActivity obsolete oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD or NADP. go-plus.json oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors http://purl.obolibrary.org/obo/GO_0050523 GO:1990693 biolink:CellularComponent intrinsic component of Golgi cis cisterna membrane The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic component of cis-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990693 GO:0050524 biolink:MolecularActivity coenzyme-B sulfoethylthiotransferase activity Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB. UM-BBD_reactionID:r0356|RHEA:12532|EC:2.8.4.1|KEGG_REACTION:R04541|MetaCyc:METHYL-COM-HTP-RXN go-plus.json 2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity|methyl-CoM reductase activity|coenzyme-B sulphoethylthiotransferase activity|methyl coenzyme M reductase activity|methyl-coenzyme-M reductase activity http://purl.obolibrary.org/obo/GO_0050524 GO:1990694 biolink:CellularComponent intrinsic component of Golgi medial cisterna membrane The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic component of medial-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990694 GO:0050529 biolink:MolecularActivity polyneuridine-aldehyde esterase activity Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol. EC:3.1.1.78|KEGG_REACTION:R05825|RHEA:17501|MetaCyc:3.1.1.78-RXN go-plus.json PNAE activity|polyneuridine aldehyde esterase activity|polyneuridine aldehyde hydrolase (decarboxylating) http://purl.obolibrary.org/obo/GO_0050529 GO:0050527 biolink:MolecularActivity poly(3-hydroxyoctanoate) depolymerase activity Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5. EC:3.1.1.76|MetaCyc:3.1.1.76-RXN go-plus.json poly(3HO) depolymerase activity|poly((R)-3-hydroxyoctanoate) hydrolase activity|poly((R)-hydroxyalkanoic acid) depolymerase activity|poly[(R)-3-hydroxyoctanoate] hydrolase activity|poly(HAMCL) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|PHA depolymerase activity|poly(HA(MCL)) depolymerase activity|PHO depolymerase activity|poly(HA) depolymerase activity|poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity http://purl.obolibrary.org/obo/GO_0050527 GO:1990690 biolink:BiologicalProcess Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. go-plus.json medial-Golgi cisterna-derived vesicle fusion with cis-Golgi cisterna membrane http://purl.obolibrary.org/obo/GO_1990690 GO:0050528 biolink:MolecularActivity acyloxyacyl hydrolase activity Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid. EC:3.1.1.77|RHEA:12032|MetaCyc:3.1.1.77-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0050528 PO:0009088 biolink:OntologyClass seed coat A portion of plant tissue that is the covering of a seed derived from ovular - mainly integumentary - tissue. go-plus.json 種子種皮 (Japanese, exact)|portion of seed coat tissue (exact)|cubierta de la semilla (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009088 CHEBI:76460 biolink:ChemicalSubstance (3R,7Z,10Z,13Z,16Z,19Z)-3-hydroxydocosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76460 chebi_ph7_3 CHEBI:76463 biolink:ChemicalSubstance (3R)-3-hydroxytetracosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76463 CHEBI:76464 biolink:ChemicalSubstance (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76464 chebi_ph7_3 CHEBI:76461 biolink:ChemicalSubstance (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76461 chebi_ph7_3 CHEBI:76462 biolink:ChemicalSubstance (3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76462 chebi_ph7_3 PO:0009089 biolink:OntologyClass endosperm A portion of plant tissue (PO:0009007) which is a maximal portion of nutritive plant tissue in a seed (PO:0009010). go-plus.json albumen (exact)|endosperma (Spanish, exact)|内胚乳、胚乳 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009089 GO:1990699 biolink:MolecularActivity palmitoleyl hydrolase activity Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate. go-plus.json http://purl.obolibrary.org/obo/GO_1990699 CHEBI:76467 biolink:ChemicalSubstance (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76467 chebi_ph7_3 CHEBI:76468 biolink:ChemicalSubstance (3R,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76468 chebi_ph7_3 CHEBI:76465 biolink:ChemicalSubstance (R)-3-hydroxyhexacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76465 CHEBI:76466 biolink:ChemicalSubstance (3R,11Z,14Z,17Z,20Z,23Z)-3-hydroxyhexacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76466 chebi_ph7_3 GO:0050532 biolink:MolecularActivity 2-phosphosulfolactate phosphatase activity Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate. MetaCyc:R229-RXN|RHEA:23416|KEGG_REACTION:R05789|EC:3.1.3.71 go-plus.json (2R)-phosphosulfolactate phosphohydrolase activity|ComB phosphatase activity|(R)-2-phospho-3-sulfolactate phosphohydrolase activity|2-phosphosulpholactate phosphatase activity http://purl.obolibrary.org/obo/GO_0050532 GO:0050533 biolink:MolecularActivity 5-phytase activity Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate. MetaCyc:3.1.3.72-RXN|EC:3.1.3.72|RHEA:13001 go-plus.json myo-inositol-hexakisphosphate 5-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050533 GO:0050530 biolink:MolecularActivity glucosylglycerol 3-phosphatase activity Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate. EC:3.1.3.69|RHEA:22652|KEGG_REACTION:R05791|MetaCyc:3.1.3.69-RXN go-plus.json StpA|2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity|salt tolerance protein A http://purl.obolibrary.org/obo/GO_0050530 GO:0050531 biolink:MolecularActivity mannosyl-3-phosphoglycerate phosphatase activity Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate. MetaCyc:3.1.3.70-RXN|RHEA:19309|EC:3.1.3.70|KEGG_REACTION:R05790 go-plus.json alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050531 GO:0050536 biolink:MolecularActivity (S)-N-acetyl-1-phenylethylamine hydrolase activity Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine. MetaCyc:3.5.1.85-RXN|RHEA:23952|EC:3.5.1.85|KEGG_REACTION:R07301 go-plus.json (S)-N-acetyl-1-phenylethylamine amidohydrolase activity|(S)-N-acetylphenylethylamine:H2O hydrolase activity http://purl.obolibrary.org/obo/GO_0050536 GO:0050537 biolink:MolecularActivity mandelamide amidase activity Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+). MetaCyc:3.5.1.86-RXN|RHEA:22876|EC:3.5.1.86|KEGG_REACTION:R05783 go-plus.json Pseudomonas mandelamide hydrolase activity|mandelamide hydrolase activity http://purl.obolibrary.org/obo/GO_0050537 GO:0050534 biolink:MolecularActivity 3-deoxyoctulosonase activity Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide. MetaCyc:3.2.1.144-RXN|EC:3.2.1.144 go-plus.json alpha-Kdo-ase activity|3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity http://purl.obolibrary.org/obo/GO_0050534 GO:0050535 biolink:MolecularActivity beta-primeverosidase activity Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol. MetaCyc:3.2.1.149-RXN|EC:3.2.1.149|RHEA:24480 go-plus.json b-primeverosidase activity|6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity http://purl.obolibrary.org/obo/GO_0050535 GO:0050538 biolink:MolecularActivity N-carbamoyl-L-amino-acid hydrolase activity Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate. RHEA:17581|MetaCyc:3.5.1.87-RXN|EC:3.5.1.87 go-plus.json N-carbamoyl-L-amino acid amidohydrolase activity|L-carbamoylase activity http://purl.obolibrary.org/obo/GO_0050538 GO:0050539 biolink:MolecularActivity maleimide hydrolase activity Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate. EC:3.5.2.16|RHEA:24476|KEGG_REACTION:R05781|MetaCyc:3.5.2.16-RXN go-plus.json cyclic-imide amidohydrolase (decyclizing)|cyclic imide hydrolase activity|cyclic-imide amidohydrolase (decyclicizing)|imidase activity http://purl.obolibrary.org/obo/GO_0050539 PO:0009074 biolink:OntologyClass style A cardinal organ part (PO:0025001) which is an elongated part of a carpel (PO:0009030) or gynoecium (PO:0009062) between the plant ovary (PO:0009072) and the stigma (PO:0009073), and through which the pollen tube (GO:0090406) grows. go-plus.json 花柱 (Japanese, exact)|Poaceae style (narrow)|estilo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0009074 CHEBI:76470 biolink:ChemicalSubstance (3R,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76470 chebi_ph7_3 PO:0009071 biolink:OntologyClass anther wall tapetum A microsporangium tapetum (PO:0025314) that is part of an anther wall (PO:0000002). go-plus.json Poaceae tapetum (narrow)|pollen sac tapetum (exact)|tapete (Spanish, exact)|portion of anther wall tapetal tissue (exact)|Zea tapetum (narrow)|葯壁タペート組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0009071 CHEBI:76471 biolink:ChemicalSubstance (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76471 chebi_ph7_3 PO:0009072 biolink:OntologyClass plant ovary A plant structure (PO:0009011) that is the basal portion of a carpel (PO:0009030) or group of fused carpels (gynoecium; PO:0009062) and encloses the plant ovule(s) (PO:0020003). go-plus.json ovario vegetal (Spanish, exact)|Zea ovary (narrow)|子房 (Japanese, exact)|Poaceae ovary (narrow) http://purl.obolibrary.org/obo/PO_0009072 PO:0009073 biolink:OntologyClass stigma A cardinal organ part (PO:0025001), usually apical, that is part of a carpel (PO:0009030) or group of fused carpels on which the pollen (PO:0025281) germinates. go-plus.json stigmata (exact, plural)|stigmas (exact, plural)|柱頭 (Japanese, exact)|estigma (Spanish, exact)|Zea stigma (narrow)|Poaceae stigma (narrow) http://purl.obolibrary.org/obo/PO_0009073 CHEBI:76474 biolink:ChemicalSubstance (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76474 chebi_ph7_3 CHEBI:76475 biolink:ChemicalSubstance (3R,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76475 chebi_ph7_3 CHEBI:76472 biolink:ChemicalSubstance (R)-3-hydroxyoctacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76472 CHEBI:76473 biolink:ChemicalSubstance (3R,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76473 chebi_ph7_3 CHEBI:76478 biolink:ChemicalSubstance dibutyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_76478 chebi_ph7_3 CHEBI:76479 biolink:ChemicalSubstance (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76479 chebi_ph7_3 CHEBI:76476 biolink:ChemicalSubstance (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76476 chebi_ph7_3 CHEBI:76477 biolink:ChemicalSubstance (3R,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76477 chebi_ph7_3 NCBITaxon:1301 biolink:OrganismalEntity Streptococcus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1301 CHEBI:47003 biolink:ChemicalSubstance leucine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_47003 CHEBI:47004 biolink:ChemicalSubstance alpha-L-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47004 chebi_ph7_3 CHEBI:47005 biolink:ChemicalSubstance beta-L-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47005 chebi_ph7_3 CHEBI:47006 biolink:ChemicalSubstance D-ribopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47006 chebi_ph7_3 UBERON:0000457 biolink:AnatomicalEntity cavernous artery Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses. go-plus.json cavernous branch of cavernous part of internal carotid artery|ramus sinus cavernosi (pars cavernosa) (arteria carotis interna) http://purl.obolibrary.org/obo/UBERON_0000457 CHEBI:47007 biolink:ChemicalSubstance ribopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47007 UBERON:0000458 biolink:AnatomicalEntity endocervix The region of the opening of the uterine cervix into the uterine cavity. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000458 UBERON:0000459 biolink:AnatomicalEntity uterine wall An anatomical wall that is part of a uterus [Automatically generated definition]. go-plus.json anatomical wall of uterus|uterus anatomical wall|uterus wall|wall of uterus http://purl.obolibrary.org/obo/UBERON_0000459 NCBITaxon:1300 biolink:OrganismalEntity Streptococcaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1300 CHEBI:62641 biolink:ChemicalSubstance perillate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62641 chebi_ph7_3 CHEBI:47000 biolink:ChemicalSubstance L-ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47000 chebi_ph7_3 CHEBI:47002 biolink:ChemicalSubstance beta-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47002 chebi_ph7_3 CHEBI:37677 biolink:ChemicalSubstance L-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37677 chebi_ph7_3 CHEBI:37676 biolink:ChemicalSubstance L-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37676 CHEBI:62643 biolink:ChemicalSubstance anionic phospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62643 CHEBI:62649 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_62649 chebi_ph7_3 CHEBI:37679 biolink:ChemicalSubstance beta-L-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37679 chebi_ph7_3 UBERON:0000464 biolink:AnatomicalEntity anatomical space Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. go-plus.json anatomical spaces|lumen|space|lumen space http://purl.obolibrary.org/obo/UBERON_0000464 UBERON:0000465 biolink:AnatomicalEntity material anatomical entity Anatomical entity that has mass. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000465 CHEBI:37670 biolink:ChemicalSubstance protease inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_37670 UBERON:0000466 biolink:AnatomicalEntity immaterial anatomical entity Anatomical entity that has no mass. go-plus.json immaterial physical anatomical entity http://purl.obolibrary.org/obo/UBERON_0000466 UBERON:0000467 biolink:AnatomicalEntity anatomical system Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. go-plus.json system|anatomical systems|organ system|connected anatomical system|body system http://purl.obolibrary.org/obo/UBERON_0000467 CHEBI:37673 biolink:ChemicalSubstance ajmalan go-plus.json http://purl.obolibrary.org/obo/CHEBI_37673 CHEBI:37674 biolink:ChemicalSubstance 17-O-acetylajmaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_37674 CHEBI:37671 biolink:ChemicalSubstance (1->3)-beta-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_37671 chebi_ph7_3 UBERON:0000463 biolink:AnatomicalEntity organism substance Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. go-plus.json organism substance|portion of body substance|body substance|portion of organism substance|body fluid or substance http://purl.obolibrary.org/obo/UBERON_0000463 NCBITaxon:1313 biolink:OrganismalEntity Streptococcus pneumoniae go-plus.json Micrococcus pneumoniae|Diplococcus pneumoniae http://purl.obolibrary.org/obo/NCBITaxon_1313 CHEBI:23048 biolink:ChemicalSubstance carvones go-plus.json http://purl.obolibrary.org/obo/CHEBI_23048 CHEBI:23045 biolink:ChemicalSubstance carotenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23045 GO:0001700 biolink:BiologicalProcess embryonic development via the syncytial blastoderm The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0001700 CHEBI:23046 biolink:ChemicalSubstance carveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23046 chebi_ph7_3 CHEBI:62651 biolink:ChemicalSubstance thia-alkylglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62651 CHEBI:23043 biolink:ChemicalSubstance epoxycarotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23043 CHEBI:23044 biolink:ChemicalSubstance carotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23044 CHEBI:23041 biolink:ChemicalSubstance carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_23041 CHEBI:23042 biolink:ChemicalSubstance carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23042 GO:0001709 biolink:BiologicalProcess cell fate determination A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. Wikipedia:Cell_fate_determination go-plus.json http://purl.obolibrary.org/obo/GO_0001709 GO:0001705 biolink:BiologicalProcess ectoderm formation The formation of ectoderm during gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0001705 CHEBI:37680 biolink:ChemicalSubstance alpha-L-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37680 chebi_ph7_3 GO:0001706 biolink:BiologicalProcess endoderm formation The formation of the endoderm during gastrulation. go-plus.json endoblast formation http://purl.obolibrary.org/obo/GO_0001706 UBERON:0000454 biolink:AnatomicalEntity cerebral subcortex The layer located below the cerebral cortex that includes the forebrain, midbrain and hindbrain. go-plus.json cerebral medulla|subcortex http://purl.obolibrary.org/obo/UBERON_0000454 GO:0001707 biolink:BiologicalProcess mesoderm formation The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0001707 UBERON:0000456 biolink:AnatomicalEntity secretion of exocrine gland A portion of organism substance that is produced by exocrine glands. go-plus.json bodily secretion|secretion|exocrine gland fluid|exocrine gland fluid or secretion|secreted substance|external secretion|exocrine gland secretion|exocrine gland fluid/secretion http://purl.obolibrary.org/obo/UBERON_0000456 GO:0001708 biolink:BiologicalProcess cell fate specification The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. go-plus.json http://purl.obolibrary.org/obo/GO_0001708 GO:0001701 biolink:BiologicalProcess in utero embryonic development The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0001701 CHEBI:37684 biolink:ChemicalSubstance mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37684 chebi_ph7_3 GO:0001702 biolink:BiologicalProcess gastrulation with mouth forming second A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. go-plus.json deuterostomic gastrulation http://purl.obolibrary.org/obo/GO_0001702 GO:0001703 biolink:BiologicalProcess gastrulation with mouth forming first A gastrulation process in which the initial invagination becomes the mouth and the anus forms second. go-plus.json protostomic gastrulation http://purl.obolibrary.org/obo/GO_0001703 GO:0001704 biolink:BiologicalProcess formation of primary germ layer The formation of the ectoderm, mesoderm and endoderm during gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0001704 CHEBI:37683 biolink:ChemicalSubstance mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37683 UBERON:0000439 biolink:AnatomicalEntity arachnoid trabecula The arachnoid trabeculae are delicate strands of connective tissue that loosely connect the two innermost layers of the meninges -- the arachnoid mater and the pia mater. They are found within the subarachnoid space where cerebrospinal fluid is also found. Embryologically, the trabeculae are the remnants of the common precursor that forms both the arachnoid and pial layers of the meninges. go-plus.json trabecula arachnoideum|arachnoid trabeculae http://purl.obolibrary.org/obo/UBERON_0000439 CHEBI:23014 biolink:ChemicalSubstance carbon oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23014 CHEBI:23012 biolink:ChemicalSubstance carbon disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23012 chebi_ph7_3 CHEBI:23018 biolink:ChemicalSubstance EC 4.2.1.1 (carbonic anhydrase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_23018 CHEBI:23019 biolink:ChemicalSubstance carbonyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_23019 chebi_ph7_3 CHEBI:23016 biolink:ChemicalSubstance carbonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_23016 CHEBI:62663 biolink:ChemicalSubstance hydroxy-alkenylglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62663 CHEBI:37655 biolink:ChemicalSubstance D-erythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37655 CHEBI:37653 biolink:ChemicalSubstance phosphoerythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37653 CHEBI:37654 biolink:ChemicalSubstance erythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37654 CHEBI:37659 biolink:ChemicalSubstance oleanolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37659 UBERON:0000442 biolink:AnatomicalEntity right testicular vein A vein that drains the left pampiniform plexus and empties into the left renal vein. go-plus.json right spermatic vein|vena testicularis sinistra|vena testicularis (adrenalis) dextra|vena testicularis dextra http://purl.obolibrary.org/obo/UBERON_0000442 UBERON:0000443 biolink:AnatomicalEntity left testicular vein A vein that drains the right pampiniform plexus and empties into the inferior vena cava. go-plus.json vena testicularis sinistra|left spermatic vein|vena testicularis dextra http://purl.obolibrary.org/obo/UBERON_0000443 UBERON:0000444 biolink:AnatomicalEntity lymphoid follicle . go-plus.json nodulus lymphoideus|lymphatic nodule|nodular lymphoid tissue|lymphoid nodule|nodulus lymphaticus|folliculus lymphaticus|lymphatic follicle http://purl.obolibrary.org/obo/UBERON_0000444 CHEBI:37651 biolink:ChemicalSubstance pyrimidine ribonucleoside 2'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37651 UBERON:0000440 biolink:AnatomicalEntity trabecula A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000440 CHEBI:37650 biolink:ChemicalSubstance ribonucleoside 2'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37650 UBERON:0000428 biolink:AnatomicalEntity prostate epithelium The prostate epithelium. go-plus.json prostate epithelial tissue|prostatic epithelium|epithelial tissue of prostate gland|epithelium of prostate gland|prostate gland epithelial tissue|epithelium of prostatic gland|prostatic gland epithelium|epithelial tissue of prostate|epithelium of prostate|prostate gland epithelium http://purl.obolibrary.org/obo/UBERON_0000428 UBERON:0000429 biolink:AnatomicalEntity enteric plexus A plexus of autonomic nerve fibers within the wall of the digestive tube, and made up of the submucosal, myenteric, and subserosal plexuses; it contains visceral afferent fibers, sympathetic postganglionic fibers, parasympathetic preganglionic and postganglionic fibers, and parasympathetic postganglionic cell bodies. go-plus.json plexus nervosus entericus|intrinsic nerve plexus|plexus entericus|sympathetic enteric nerve plexus|enteric nerve plexus http://purl.obolibrary.org/obo/UBERON_0000429 CHEBI:23022 biolink:ChemicalSubstance carboxy-2-hydroxymuconate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_23022 CHEBI:37667 biolink:ChemicalSubstance sesquiterpene lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37667 CHEBI:37668 biolink:ChemicalSubstance terpene lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37668 CHEBI:37669 biolink:ChemicalSubstance methanopterins go-plus.json http://purl.obolibrary.org/obo/CHEBI_37669 CHEBI:37662 biolink:ChemicalSubstance aldehydo-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37662 CHEBI:37661 biolink:ChemicalSubstance glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37661 CHEBI:72003 biolink:ChemicalSubstance 3-hydroxyisoheptadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_72003 CHEBI:72004 biolink:ChemicalSubstance hexadec-9-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72004 NCBITaxon:59201 biolink:OrganismalEntity Salmonella enterica subsp. enterica go-plus.json Salmonella enterica subsp. Subsp. I|Salmonella enterica I|Salmonella enterica subsp. Subsp. Ixxx|Salmonella cholerae-suis subsp. cholerae-suis|Salmonella choleraesuis subsp. choleraesuis|Salmonella enterica subsp. I http://purl.obolibrary.org/obo/NCBITaxon_59201 CHEBI:72006 biolink:ChemicalSubstance (E)-isoheptadec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_72006 CHEBI:37639 biolink:ChemicalSubstance polysaccharide phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37639 CHEBI:62682 biolink:ChemicalSubstance inositol phosphomannosylinositol phosphoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62682 OPL:0000232 biolink:OntologyClass parasite organism An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class. go-plus.json http://purl.obolibrary.org/obo/OPL_0000232 CHEBI:37631 biolink:ChemicalSubstance beta-L-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37631 chebi_ph7_3 CHEBI:37630 biolink:ChemicalSubstance alpha-L-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37630 chebi_ph7_3 CHEBI:72000 biolink:ChemicalSubstance (3E,5Z)-tetradecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72000 CHEBI:72001 biolink:ChemicalSubstance (3E,5Z)-tetradecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_72001 CHEBI:23003 biolink:ChemicalSubstance carbamate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_23003 CHEBI:23004 biolink:ChemicalSubstance carbamoyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_23004 chebi_ph7_3 CHEBI:23007 biolink:ChemicalSubstance carbohydrate-containing antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_23007 CHEBI:72019 biolink:ChemicalSubstance N-octacosanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72019 chebi_ph7_3 CHEBI:23000 biolink:ChemicalSubstance caprolactams go-plus.json http://purl.obolibrary.org/obo/CHEBI_23000 CHEBI:86644 biolink:ChemicalSubstance Gibberellic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86644 UBERON:0000490 biolink:AnatomicalEntity unilaminar epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA] go-plus.json unilaminar epithelia|simple epithelium http://purl.obolibrary.org/obo/UBERON_0000490 CHEBI:37645 biolink:ChemicalSubstance luteolin 7-O-[(beta-D-glucosyluronic acid)-(1->2)-(beta-D-glucosiduronic acid)] 4'-O-beta-D-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37645 CHEBI:37642 biolink:ChemicalSubstance (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_37642 CHEBI:37643 biolink:ChemicalSubstance (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_37643 CHEBI:37649 biolink:ChemicalSubstance purine ribonucleoside 2'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37649 CHEBI:86649 biolink:ChemicalSubstance Guanidineacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86649 CHEBI:37646 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37646 CHEBI:72010 biolink:ChemicalSubstance hydroxyflavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_72010 CHEBI:37640 biolink:ChemicalSubstance (24S)-7alpha,24-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37640 chebi_ph7_3 UBERON:0000479 biolink:AnatomicalEntity tissue Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. go-plus.json portion of tissue|tissue portion|simple tissue http://purl.obolibrary.org/obo/UBERON_0000479 CHEBI:37619 biolink:ChemicalSubstance L-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37619 chebi_ph7_3 CHEBI:37617 biolink:ChemicalSubstance aldehydo-L-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37617 chebi_ph7_3 CHEBI:37618 biolink:ChemicalSubstance L-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37618 CHEBI:37611 biolink:ChemicalSubstance cyclohexa-1,4-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37611 chebi_ph7_3 OPL:0000215 biolink:OntologyClass Glossina midgut A midgut that is a part of or originated from a tsetse fly of genus Glossina. go-plus.json http://purl.obolibrary.org/obo/OPL_0000215 CHEBI:37610 biolink:ChemicalSubstance cyclohexa-1,3-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37610 chebi_ph7_3 UBERON:0000481 biolink:AnatomicalEntity multi-tissue structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. go-plus.json multi-tissue structures http://purl.obolibrary.org/obo/UBERON_0000481 CHEBI:37613 biolink:ChemicalSubstance cyclohexadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37613 CHEBI:37614 biolink:ChemicalSubstance alkenyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37614 UBERON:0000486 biolink:AnatomicalEntity multilaminar epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA] go-plus.json stratified epithelium|laminated epithelium http://purl.obolibrary.org/obo/UBERON_0000486 UBERON:0000487 biolink:AnatomicalEntity simple squamous epithelium Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA] go-plus.json simple squamous epithelia|epithelium simplex squamosum http://purl.obolibrary.org/obo/UBERON_0000487 UBERON:0000488 biolink:AnatomicalEntity atypical epithelium Epithelium that consists of epithelial cells not arranged in one ore more layers. go-plus.json heterogenous epithelium|atypical epithelia http://purl.obolibrary.org/obo/UBERON_0000488 UBERON:0000489 biolink:AnatomicalEntity cavitated compound organ Compound organ that contains one or more macroscopic anatomical spaces. go-plus.json cavitated compound organs|cavitated organ http://purl.obolibrary.org/obo/UBERON_0000489 UBERON:0000483 biolink:AnatomicalEntity epithelium Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. go-plus.json portion of epithelium|epithelial tissue http://purl.obolibrary.org/obo/UBERON_0000483 UBERON:0000484 biolink:AnatomicalEntity simple cuboidal epithelium Unilaminar epithelium that consists of a single layer of cuboidal cells. go-plus.json simple cuboidal epithelia|epithelium simplex cuboideum http://purl.obolibrary.org/obo/UBERON_0000484 UBERON:0000485 biolink:AnatomicalEntity simple columnar epithelium Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA] go-plus.json columnar epithlium|simple columnar epithelia|columnar epithelium|simple columnar epithelium|epithelium simplex columnare http://purl.obolibrary.org/obo/UBERON_0000485 UBERON:0000468 biolink:AnatomicalEntity multicellular organism Anatomical structure that is an individual member of a species and consists of more than one cell. go-plus.json Koerper|organism|whole body|animal|body|whole organism|multi-cellular organism http://purl.obolibrary.org/obo/UBERON_0000468 CHEBI:37622 biolink:ChemicalSubstance carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37622 chebi_ph7_3 CHEBI:37623 biolink:ChemicalSubstance 7alpha,25-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37623 chebi_ph7_3 CHEBI:37620 biolink:ChemicalSubstance beta-L-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37620 chebi_ph7_3 CHEBI:37621 biolink:ChemicalSubstance galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37621 CHEBI:37627 biolink:ChemicalSubstance L-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37627 chebi_ph7_3 CHEBI:37624 biolink:ChemicalSubstance L-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37624 UBERON:0000475 biolink:AnatomicalEntity organism subdivision Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. go-plus.json body region|cardinal body part|body part|anatomic region http://purl.obolibrary.org/obo/UBERON_0000475 UBERON:0000476 biolink:AnatomicalEntity acellular anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. go-plus.json acellular anatomical structures http://purl.obolibrary.org/obo/UBERON_0000476 UBERON:0000477 biolink:AnatomicalEntity anatomical cluster Anatomical group that has its parts adjacent to one another. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000477 UBERON:0000478 biolink:AnatomicalEntity extraembryonic structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. go-plus.json extraembryonic tissue|extraembryonic structures|extra-embryonic structure http://purl.obolibrary.org/obo/UBERON_0000478 UBERON:0000471 biolink:AnatomicalEntity compound organ component Multi-tissue structure that is part of a compound organ. go-plus.json compound organ components http://purl.obolibrary.org/obo/UBERON_0000471 UBERON:0000473 biolink:AnatomicalEntity testis A gonad of a male animal. A gonad produces and releases sperm. go-plus.json gonad of male reproductive system|orchis|testicle|gonad of male genitalia|testiculus|testes|male gonad http://purl.obolibrary.org/obo/UBERON_0000473 UBERON:0000474 biolink:AnatomicalEntity female reproductive system The organs and associated structures associated with bearing offspring in a female animal. go-plus.json reproductive system of female organism|female genitalia|female organism genitalia|gynaecological tissue|female genital tract|female reproductive tract|genitalia of female organism|female genitals|female organism reproductive system|female genital system|systema genitale femininum http://purl.obolibrary.org/obo/UBERON_0000474 GO:0001774 biolink:BiologicalProcess microglial cell activation The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0001774 GO:0098686 biolink:CellularComponent hippocampal mossy fiber to CA3 synapse One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098686 goslim_synapse GO:0098687 biolink:CellularComponent chromosomal region Any subdivision of a chromosome along its length. go-plus.json chromosome region http://purl.obolibrary.org/obo/GO_0098687 GO:0001775 biolink:BiologicalProcess cell activation A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0001775 goslim_pir GO:0098684 biolink:CellularComponent photoreceptor ribbon synapse A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon. go-plus.json http://purl.obolibrary.org/obo/GO_0098684 goslim_synapse GO:0001776 biolink:BiologicalProcess leukocyte homeostasis The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json leucocyte homeostasis|immune cell homeostasis http://purl.obolibrary.org/obo/GO_0001776 GO:0098685 biolink:CellularComponent Schaffer collateral - CA1 synapse A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098685 goslim_synapse GO:0001777 biolink:BiologicalProcess T cell homeostatic proliferation The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. go-plus.json T-lymphocyte homeostatic proliferation|resting T-cell proliferation|T lymphocyte homeostatic proliferation|resting T cell proliferation|T-cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0001777 GO:0001770 biolink:BiologicalProcess establishment of natural killer cell polarity The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands. go-plus.json NK cell polarization|establishment of NK cell polarity|natural killer cell polarization http://purl.obolibrary.org/obo/GO_0001770 GO:0098682 biolink:CellularComponent arciform density An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098682 NCBITaxon:1385 biolink:OrganismalEntity Bacillales go-plus.json Bacillus/Staphylococcus group http://purl.obolibrary.org/obo/NCBITaxon_1385 GO:0098683 biolink:CellularComponent cochlear hair cell ribbon synapse A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density. go-plus.json http://purl.obolibrary.org/obo/GO_0098683 goslim_synapse GO:0001771 biolink:BiologicalProcess immunological synapse formation The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. go-plus.json formation of immunological synapse http://purl.obolibrary.org/obo/GO_0001771 NCBITaxon:1386 biolink:OrganismalEntity Bacillus go-plus.json Bacillus|Bacillus rRNA group 1 http://purl.obolibrary.org/obo/NCBITaxon_1386 GO:0098680 biolink:MolecularActivity template-free RNA nucleotidyltransferase Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template. go-plus.json http://purl.obolibrary.org/obo/GO_0098680 GO:0001772 biolink:CellularComponent immunological synapse An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. Wikipedia:Immunological_synapse go-plus.json supramolecular activation cluster|c-SMAC http://purl.obolibrary.org/obo/GO_0001772 GO:0001773 biolink:BiologicalProcess myeloid dendritic cell activation The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0001773 GO:0098681 biolink:CellularComponent synaptic ribbon A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical. go-plus.json http://purl.obolibrary.org/obo/GO_0098681 GO:0060070 biolink:BiologicalProcess canonical Wnt signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. go-plus.json canonical Wnt-activated signaling pathway|Wnt receptor signaling pathway through beta-catenin|canonical Wnt receptor signaling pathway|Wnt receptor signalling pathway through beta-catenin|Wnt receptor signaling pathway via beta-catenin|frizzled-1 receptor signaling pathway http://purl.obolibrary.org/obo/GO_0060070 GO:0060071 biolink:BiologicalProcess Wnt signaling pathway, planar cell polarity pathway The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity. go-plus.json Wnt receptor signalling pathway, planar cell polarity pathway|Wnt receptor signaling pathway, planar cell polarity pathway|Wnt-JNK signaling pathway|Wnt-activated signaling pathway, planar cell polarity pathway|non-canonical Wnt signaling pathway|planar cell polarity pathway|PCP pathway|Wnt-PCP signaling pathway http://purl.obolibrary.org/obo/GO_0060071 GO:0060072 biolink:MolecularActivity large conductance calcium-activated potassium channel activity Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. go-plus.json BK calcium-activated potassium channel activity|BK channel activity|BK KCa channel activity|large conductance KCa channel activity http://purl.obolibrary.org/obo/GO_0060072 GO:0060073 biolink:BiologicalProcess micturition The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. Wikipedia:Urination go-plus.json urine voiding|urination http://purl.obolibrary.org/obo/GO_0060073 GO:0060074 biolink:BiologicalProcess synapse maturation The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development. go-plus.json synaptic maturation http://purl.obolibrary.org/obo/GO_0060074 goslim_synapse GO:1902498 biolink:BiologicalProcess regulation of protein autoubiquitination Any process that modulates the frequency, rate or extent of protein autoubiquitination. go-plus.json regulation of protein self-ubiquitinylation|regulation of protein auto-ubiquitinylation|regulation of protein self-ubiquitination|regulation of protein auto-ubiquitination|regulation of protein autoubiquitinylation http://purl.obolibrary.org/obo/GO_1902498 GO:1902499 biolink:BiologicalProcess positive regulation of protein autoubiquitination Any process that activates or increases the frequency, rate or extent of protein autoubiquitination. go-plus.json up regulation of protein autoubiquitination|upregulation of protein self-ubiquitinylation|upregulation of protein auto-ubiquitinylation|up-regulation of protein self-ubiquitination|up-regulation of protein autoubiquitinylation|activation of protein autoubiquitinylation|up-regulation of protein auto-ubiquitination|upregulation of protein autoubiquitination|up regulation of protein self-ubiquitinylation|activation of protein self-ubiquitinylation|positive regulation of protein self-ubiquitinylation|upregulation of protein self-ubiquitination|up regulation of protein auto-ubiquitinylation|activation of protein auto-ubiquitinylation|positive regulation of protein auto-ubiquitinylation|positive regulation of protein autoubiquitinylation|upregulation of protein auto-ubiquitination|up-regulation of protein autoubiquitination|up regulation of protein autoubiquitinylation|activation of protein autoubiquitination|up regulation of protein self-ubiquitination|up-regulation of protein self-ubiquitinylation|activation of protein self-ubiquitination|positive regulation of protein self-ubiquitination|up-regulation of protein auto-ubiquitinylation|up regulation of protein auto-ubiquitination|activation of protein auto-ubiquitination|upregulation of protein autoubiquitinylation|positive regulation of protein auto-ubiquitination http://purl.obolibrary.org/obo/GO_1902499 GO:0060075 biolink:BiologicalProcess regulation of resting membrane potential Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized. go-plus.json regulation of resting potential http://purl.obolibrary.org/obo/GO_0060075 GO:1902496 biolink:MolecularActivity obsolete protein binding involved in negative regulation of telomere maintenance via telomerase OBSOLETE. Any protein binding that is involved in negative regulation of telomere maintenance via telomerase. go-plus.json protein binding involved in down-regulation of telomere maintenance via telomerase activity|protein binding involved in down regulation of telomere maintenance via telomerase activity|protein binding involved in downregulation of telomere maintenance via telomerase activity|protein binding involved in inhibition of telomere maintenance via telomerase http://purl.obolibrary.org/obo/GO_1902496 GO:0060076 biolink:CellularComponent excitatory synapse A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell. Wikipedia:Excitatory_synapse go-plus.json http://purl.obolibrary.org/obo/GO_0060076 GO:1902497 biolink:BiologicalProcess iron-sulfur cluster transmembrane transport A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json iron-sulfur cluster transport http://purl.obolibrary.org/obo/GO_1902497 GO:0060077 biolink:CellularComponent inhibitory synapse A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell. Wikipedia:Inhibitory_postsynaptic_potential go-plus.json http://purl.obolibrary.org/obo/GO_0060077 GO:0060078 biolink:BiologicalProcess regulation of postsynaptic membrane potential Any process that modulates the potential difference across a post-synaptic membrane. go-plus.json regulation of post-synaptic membrane potential http://purl.obolibrary.org/obo/GO_0060078 goslim_synapse GO:0060079 biolink:BiologicalProcess excitatory postsynaptic potential A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. go-plus.json regulation of excitatory post-synaptic membrane potential|regulation of EPSP http://purl.obolibrary.org/obo/GO_0060079 GO:0001778 biolink:BiologicalProcess plasma membrane repair The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress. go-plus.json http://purl.obolibrary.org/obo/GO_0001778 GO:0001779 biolink:BiologicalProcess natural killer cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell. go-plus.json NK cell differentiation|natural killer cell development http://purl.obolibrary.org/obo/GO_0001779 GO:0098688 biolink:CellularComponent parallel fiber to Purkinje cell synapse An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells. go-plus.json http://purl.obolibrary.org/obo/GO_0098688 goslim_synapse GO:0098689 biolink:BiologicalProcess latency-replication decision The process by which a virus switches on its replication cycle in an infected cell. The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli. VZ:3964 go-plus.json lytic switch|prophage induction|proviral induction|reactivation of latent virus|Latency-replication switch|proviral switch http://purl.obolibrary.org/obo/GO_0098689 GO:0098697 biolink:MolecularActivity ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. go-plus.json http://purl.obolibrary.org/obo/GO_0098697 goslim_synapse GO:0001785 biolink:MolecularActivity prostaglandin J receptor activity Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity. go-plus.json PGJ receptor activity|PGJ(2) receptor activity http://purl.obolibrary.org/obo/GO_0001785 GO:0098698 biolink:BiologicalProcess postsynaptic specialization assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098698 goslim_synapse GO:0001786 biolink:MolecularActivity phosphatidylserine binding Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0001786 GO:0001787 biolink:BiologicalProcess natural killer cell proliferation The expansion of a natural killer cell population by cell division. go-plus.json NK cell proliferation http://purl.obolibrary.org/obo/GO_0001787 GO:0098695 biolink:MolecularActivity inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. go-plus.json IP3 receptor activity involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0098695 goslim_synapse GO:0001788 biolink:BiologicalProcess antibody-dependent cellular cytotoxicity Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells. Wikipedia:Antibody-dependent_cellular_cytotoxicity|Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity go-plus.json antibody-dependent cell killing|ADCC|antibody dependent cell killing|antibody-dependent cell death|type VI hypersensitivity|antibody dependent cell death http://purl.obolibrary.org/obo/GO_0001788 GO:0098696 biolink:BiologicalProcess regulation of neurotransmitter receptor localization to postsynaptic specialization membrane Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098696 goslim_synapse GO:0001781 biolink:BiologicalProcess neutrophil apoptotic process Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. go-plus.json neutrophil programmed cell death by apoptosis|apoptosis of neutrophils|neutrophil apoptosis|programmed cell death, neutrophils|programmed cell death of neutrophils by apoptosis http://purl.obolibrary.org/obo/GO_0001781 GO:0098693 biolink:BiologicalProcess regulation of synaptic vesicle cycle Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0098693 goslim_synapse NCBITaxon:1396 biolink:OrganismalEntity Bacillus cereus go-plus.json Bacillus medusa|Bacillus endorhythmos http://purl.obolibrary.org/obo/NCBITaxon_1396 GO:0001782 biolink:BiologicalProcess B cell homeostasis The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json B lymphocyte homeostasis|B-cell homeostasis|B-lymphocyte homeostasis http://purl.obolibrary.org/obo/GO_0001782 GO:0098694 biolink:BiologicalProcess regulation of synaptic vesicle budding from presynaptic endocytic zone membrane Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098694 goslim_synapse GO:0001783 biolink:BiologicalProcess B cell apoptotic process Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. go-plus.json apoptosis of B-lymphocytes|B lymphocyte apoptosis|B-cell programmed cell death by apoptosis|programmed cell death of B cells by apoptosis|apoptosis of B-cells|programmed cell death of B lymphocytes by apoptosis|programmed cell death, B-lymphocytes|programmed cell death, B-cells|B-cell apoptosis|B lymphocyte programmed cell death by apoptosis|apoptosis of B lymphocytes|B cell programmed cell death by apoptosis|B-lymphocyte apoptosis|programmed cell death of B-cells by apoptosis|apoptosis of B cells|B cell apoptosis|programmed cell death of B-lymphocytes by apoptosis|programmed cell death, B lymphocytes|B-lymphocyte programmed cell death by apoptosis|programmed cell death, B cells http://purl.obolibrary.org/obo/GO_0001783 GO:0098691 biolink:CellularComponent dopaminergic synapse A synapse that uses dopamine as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0098691 goslim_synapse GO:0001784 biolink:MolecularActivity phosphotyrosine residue binding Binding to a phosphorylated tyrosine residue within a protein. go-plus.json phosphotyrosine binding http://purl.obolibrary.org/obo/GO_0001784 GO:0098692 biolink:CellularComponent noradrenergic synapse A synapse that uses noradrenaline as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0098692 GO:0098690 biolink:CellularComponent glycinergic synapse A synapse that uses glycine as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0098690 goslim_synapse GO:0060060 biolink:BiologicalProcess post-embryonic retina morphogenesis in camera-type eye The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage. go-plus.json http://purl.obolibrary.org/obo/GO_0060060 GO:0060061 biolink:BiologicalProcess Spemann organizer formation Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan. go-plus.json Spemann-Mangold organizer formation|Spemann's organizer formation http://purl.obolibrary.org/obo/GO_0060061 GO:0060062 biolink:BiologicalProcess Spemann organizer formation at the dorsal lip of the blastopore Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan. go-plus.json Spemann-Mangold organizer formation at the dorsal lip of the blastopore|Spemann's organizer formation at the dorsal lip of the blastopore http://purl.obolibrary.org/obo/GO_0060062 GO:0001780 biolink:BiologicalProcess neutrophil homeostasis The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0001780 GO:0060063 biolink:BiologicalProcess Spemann organizer formation at the embryonic shield Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan. go-plus.json Spemann-Mangold organizer formation at the embryonic shield|Spemann's organizer formation at the embryonic shield http://purl.obolibrary.org/obo/GO_0060063 GO:0060064 biolink:BiologicalProcess Spemann organizer formation at the anterior end of the primitive streak Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan. go-plus.json Spemann-Mangold organizer formation at the anterior end of the primitive streak|Spemann organizer formation in amniotes|Spemann's organizer formation at the anterior end of the primitive streak http://purl.obolibrary.org/obo/GO_0060064 GO:0060065 biolink:BiologicalProcess uterus development The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. go-plus.json Mullerian tract development http://purl.obolibrary.org/obo/GO_0060065 GO:0060066 biolink:BiologicalProcess oviduct development The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. go-plus.json fallopian tube development|Mullerian tract development http://purl.obolibrary.org/obo/GO_0060066 GO:0060067 biolink:BiologicalProcess cervix development The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure. go-plus.json Mullerian tract development http://purl.obolibrary.org/obo/GO_0060067 GO:0060068 biolink:BiologicalProcess vagina development The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0060068 GO:0060069 biolink:BiologicalProcess Wnt signaling pathway, regulating spindle positioning The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle. go-plus.json Wnt receptor signalling pathway, regulating spindle positioning|Wnt receptor signaling pathway, regulating spindle positioning|non-canonical Wnt signaling pathway|Wnt-activated signaling pathway, regulating spindle positioning http://purl.obolibrary.org/obo/GO_0060069 CHEBI:144748 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144748 chebi_ph7_3 GO:0001789 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001789 GO:0098699 biolink:MolecularActivity structural constituent of presynaptic actin cytoskeleton The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0098699 goslim_synapse GO:0098664 biolink:BiologicalProcess G protein-coupled serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. go-plus.json G-protein coupled serotonin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0098664 GO:0001752 biolink:BiologicalProcess compound eye photoreceptor fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. go-plus.json http://purl.obolibrary.org/obo/GO_0001752 GO:0001753 biolink:BiologicalProcess obsolete adult eye photoreceptor development (sensu Drosophila) OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye. go-plus.json adult eye photoreceptor development (sensu Drosophila) http://purl.obolibrary.org/obo/GO_0001753 GO:0098665 biolink:CellularComponent serotonin receptor complex A protein complex that is capable of serotonin receptor activity. go-plus.json 5HT receptor complex|5-HT receptor complex|5-hydroxytryptamine receptor complex http://purl.obolibrary.org/obo/GO_0098665 GO:0098662 biolink:BiologicalProcess inorganic cation transmembrane transport A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json inorganic cation membrane transport|monovalent inorganic cation transport|divalent inorganic cation transport|transmembrane inorganic cation transport http://purl.obolibrary.org/obo/GO_0098662 GO:0001754 biolink:BiologicalProcess eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0001754 GO:0098663 biolink:MolecularActivity obsolete transmembrane transporter activity involved in import into cell OBSOLETE. Any transmembrane transporter activity that is involved in importing some substance into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098663 GO:0001755 biolink:BiologicalProcess neural crest cell migration The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0001755 GO:0098660 biolink:BiologicalProcess inorganic ion transmembrane transport The process in which an inorganic ion is transported across a membrane. go-plus.json inorganic ion membrane transport|transmembrane inorganic ion transport http://purl.obolibrary.org/obo/GO_0098660 GO:0098661 biolink:BiologicalProcess inorganic anion transmembrane transport The process in which an inorganic anion is transported across a membrane. go-plus.json transmembrane inorganic anion transport|inorganic anion membrane transport http://purl.obolibrary.org/obo/GO_0098661 GO:0060090 biolink:MolecularActivity molecular adaptor activity The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. go-plus.json protein complex scaffold activity|binding, bridging|protein-containing complex scaffold activity http://purl.obolibrary.org/obo/GO_0060090 goslim_pir|goslim_drosophila GO:0001750 biolink:CellularComponent photoreceptor outer segment The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0001750 GO:0060091 biolink:CellularComponent kinocilium A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia. Wikipedia:Kinocilium go-plus.json http://purl.obolibrary.org/obo/GO_0060091 GO:0001751 biolink:BiologicalProcess compound eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0001751 GO:0060092 biolink:BiologicalProcess regulation of synaptic transmission, glycinergic Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. go-plus.json http://purl.obolibrary.org/obo/GO_0060092 GO:0060093 biolink:BiologicalProcess negative regulation of synaptic transmission, glycinergic Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. go-plus.json negative regulation of glycinergic synaptic transmission http://purl.obolibrary.org/obo/GO_0060093 GO:0060094 biolink:BiologicalProcess positive regulation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. go-plus.json positive regulation of glycinergic synaptic transmission http://purl.obolibrary.org/obo/GO_0060094 GO:0060095 biolink:BiologicalProcess zinc potentiation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. go-plus.json zinc potentiation of glycinergic synaptic transmission http://purl.obolibrary.org/obo/GO_0060095 GO:0060096 biolink:BiologicalProcess serotonin secretion, neurotransmission The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter. go-plus.json serotonin release, neurotransmission http://purl.obolibrary.org/obo/GO_0060096 CHEBI:23098 biolink:ChemicalSubstance chiro-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23098 GO:0060097 biolink:BiologicalProcess cytoskeletal rearrangement involved in phagocytosis, engulfment The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0060097 GO:0060098 biolink:BiologicalProcess membrane reorganization involved in phagocytosis, engulfment The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. go-plus.json membrane reorganisation involved in phagocytosis, engulfment http://purl.obolibrary.org/obo/GO_0060098 GO:0060099 biolink:BiologicalProcess regulation of phagocytosis, engulfment Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0060099 GO:0098668 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098668 GO:0001756 biolink:BiologicalProcess somitogenesis The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. Wikipedia:Somitogenesis go-plus.json formation of mesodermal clusters http://purl.obolibrary.org/obo/GO_0001756 GO:0098669 biolink:BiologicalProcess superinfection exclusion The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented. VZ:3971 go-plus.json http://purl.obolibrary.org/obo/GO_0098669 GO:0001757 biolink:BiologicalProcess somite specification The process in which individual somites establish identity during embryogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0001757 GO:0001758 biolink:MolecularActivity retinal dehydrogenase activity Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal. RHEA:16177|MetaCyc:RETINAL-DEHYDROGENASE-RXN|Reactome:R-HSA-5362522|EC:1.2.1.36|Reactome:R-HSA-5696101 go-plus.json retinal:NAD+ oxidoreductase activity|cytosolic retinal dehydrogenase activity http://purl.obolibrary.org/obo/GO_0001758 GO:0098666 biolink:CellularComponent G protein-coupled serotonin receptor complex A protein complex that is capable of G protein-coupled serotonin receptor activity. go-plus.json G-protein coupled serotonin receptor complex http://purl.obolibrary.org/obo/GO_0098666 GO:0001759 biolink:BiologicalProcess organ induction The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ. go-plus.json induction of an organ http://purl.obolibrary.org/obo/GO_0001759 GO:0098667 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098667 GO:0098675 biolink:CellularComponent intrinsic component of neuronal dense core vesicle membrane The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to neuronal dense core granule membrane http://purl.obolibrary.org/obo/GO_0098675 goslim_synapse GO:0001763 biolink:BiologicalProcess morphogenesis of a branching structure The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. go-plus.json branching morphogenesis http://purl.obolibrary.org/obo/GO_0001763 GO:0098676 biolink:BiologicalProcess modulation of host virulence by virus Any process by which a virus modulates the ability of its host to infect and/or damage an organism for which it is a host. Typically this involves a phage modulating the virulence of a bacterium. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production exotoxins or provide protection against host immune defenses. VZ:3965 go-plus.json http://purl.obolibrary.org/obo/GO_0098676 GO:0001764 biolink:BiologicalProcess neuron migration The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. Wikipedia:Neural_development#Neuron_migration|Wikipedia:Neuron_migration go-plus.json neuronal migration|neuron guidance|neuron chemotaxis http://purl.obolibrary.org/obo/GO_0001764 GO:0001765 biolink:BiologicalProcess membrane raft assembly The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes. go-plus.json lipid raft assembly|membrane raft formation|lipid raft formation http://purl.obolibrary.org/obo/GO_0001765 GO:0098673 biolink:BiologicalProcess inhibition of host DNA replication by virus Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication. go-plus.json http://purl.obolibrary.org/obo/GO_0098673 GO:0001766 biolink:BiologicalProcess membrane raft polarization The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity. go-plus.json membrane polarization|lipid raft polarization http://purl.obolibrary.org/obo/GO_0001766 GO:0098674 biolink:CellularComponent extrinsic component of neuronal dense core vesicle membrane The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098674 goslim_synapse GO:0098671 biolink:BiologicalProcess adhesion receptor-mediated virion attachment to host cell The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located. VZ:3943 go-plus.json viral attachment to host adhesion receptor http://purl.obolibrary.org/obo/GO_0098671 GO:0001760 biolink:MolecularActivity aminocarboxymuconate-semialdehyde decarboxylase activity Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2). EC:4.1.1.45|KEGG_REACTION:R04323|RHEA:16557|MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN go-plus.json picolinic acid decarboxylase activity|picolinic acid carboxylase activity|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity|2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity|alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity|ACMSD activity|alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity http://purl.obolibrary.org/obo/GO_0001760 GO:0098672 biolink:BiologicalProcess evasion by virus of CRISPR-cas system Any process, either active or passive, by which a virus evades the CRISPR-cas system of its host. Some viruses can directly suppress the CRISPR system. VZ:3962 go-plus.json CRISPR-cas system evasion by virus http://purl.obolibrary.org/obo/GO_0098672 GO:0001761 biolink:MolecularActivity beta-alanine transmembrane transporter activity Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid. go-plus.json beta-alanine transporter activity http://purl.obolibrary.org/obo/GO_0001761 GO:0001762 biolink:BiologicalProcess beta-alanine transport The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0001762 GO:0060080 biolink:BiologicalProcess inhibitory postsynaptic potential A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. go-plus.json regulation of inhibitory post-synaptic membrane potential|IPSP http://purl.obolibrary.org/obo/GO_0060080 GO:0098670 biolink:BiologicalProcess entry receptor-mediated virion attachment to host cell The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration. VZ:3942 go-plus.json viral attachment to host entry receptor http://purl.obolibrary.org/obo/GO_0098670 GO:0060081 biolink:BiologicalProcess membrane hyperpolarization The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0060081 GO:0060082 biolink:BiologicalProcess eye blink reflex The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing. go-plus.json nictitating membrane reflex http://purl.obolibrary.org/obo/GO_0060082 GO:0060083 biolink:BiologicalProcess smooth muscle contraction involved in micturition The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body. go-plus.json smooth muscle contraction involved in urination|urinary bladder smooth muscle contraction involved in micturition http://purl.obolibrary.org/obo/GO_0060083 GO:0060084 biolink:BiologicalProcess synaptic transmission involved in micturition The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body. go-plus.json synaptic transmission involved in urination http://purl.obolibrary.org/obo/GO_0060084 GO:0060085 biolink:BiologicalProcess smooth muscle relaxation of the bladder outlet A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body. go-plus.json synaptic transmission involved in urination http://purl.obolibrary.org/obo/GO_0060085 GO:0060086 biolink:BiologicalProcess circadian temperature homeostasis Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours. go-plus.json circadian thermoregulation|circadian regulation of body temperature http://purl.obolibrary.org/obo/GO_0060086 GO:0060087 biolink:BiologicalProcess relaxation of vascular associated smooth muscle A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. go-plus.json vascular smooth muscle relaxation|relaxation of vascular smooth muscle|negative regulation of relaxation of vascular smooth muscle|positive regulation of relaxation of vascular smooth muscle|regulation of relaxation of vascular smooth muscle http://purl.obolibrary.org/obo/GO_0060087 GO:0060088 biolink:BiologicalProcess auditory receptor cell stereocilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells. go-plus.json auditory receptor cell stereocilium organization and biogenesis|auditory receptor cell stereocilium organisation http://purl.obolibrary.org/obo/GO_0060088 GO:0060089 biolink:MolecularActivity molecular transducer activity A compound molecular function in which an effector function is controlled by one or more regulatory components. go-plus.json http://purl.obolibrary.org/obo/GO_0060089 gocheck_do_not_manually_annotate|goslim_pir GO:0001767 biolink:BiologicalProcess establishment of lymphocyte polarity The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. go-plus.json lymphocyte polarization http://purl.obolibrary.org/obo/GO_0001767 GO:0098679 biolink:BiologicalProcess obsolete regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate catabloism. go-plus.json regulation of carbohydrate catabolism by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0098679 GO:0001768 biolink:BiologicalProcess establishment of T cell polarity The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. go-plus.json establishment of T-cell polarity|T-cell polarization|establishment of T lymphocyte polarity|T lymphocyte polarization|establishment of T-lymphocyte polarity|T cell polarization http://purl.obolibrary.org/obo/GO_0001768 CHEBI:144729 biolink:ChemicalSubstance L-beta-ethynylserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_144729 chebi_ph7_3 GO:0098677 biolink:BiologicalProcess virion maturation Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection. UniProtKB-KW:KW-0917|VZ:1946 go-plus.json viral particle maturation|virus particle maturation http://purl.obolibrary.org/obo/GO_0098677 GO:0001769 biolink:BiologicalProcess establishment of B cell polarity The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. go-plus.json establishment of B lymphocyte polarity|B lymphocyte polarization|establishment of B-lymphocyte polarity|B cell polarization|establishment of B-cell polarity|B-cell polarization http://purl.obolibrary.org/obo/GO_0001769 GO:0098678 biolink:BiologicalProcess viral tropism switching A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase. VZ:4498 go-plus.json http://purl.obolibrary.org/obo/GO_0098678 GO:0001730 biolink:MolecularActivity 2'-5'-oligoadenylate synthetase activity Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA. Reactome:R-HSA-8983680|EC:2.7.7.84|MetaCyc:RXN-13648|MetaCyc:RXN-10798|Reactome:R-HSA-8985091|RHEA:34407|Reactome:R-HSA-8985104 go-plus.json oligo-2',5'-adenylate synthetase activity|2'-5' oligoadenylate synthetase activity|(2-5')oligo(A) synthetase activity|2-5A synthetase activity http://purl.obolibrary.org/obo/GO_0001730 GO:0001731 biolink:BiologicalProcess formation of translation preinitiation complex The joining of the small ribosomal subunit, ternary complex, and mRNA. go-plus.json translation preinitiation complex assembly|formation of translation pre-initiation complex http://purl.obolibrary.org/obo/GO_0001731 GO:0001732 biolink:BiologicalProcess formation of cytoplasmic translation initiation complex Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site. go-plus.json translation initiation complex assembly|cytoplasmic translation initiation complex assembly|formation of translation initiation complex http://purl.obolibrary.org/obo/GO_0001732 GO:0001733 biolink:MolecularActivity galactosylceramide sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate. MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN|RHEA:43304|EC:2.8.2.11 go-plus.json GSase|3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity|3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity|galactolipid sulfotransferase activity|cerebroside sulfotransferase activity|glycosphingolipid sulfotransferase activity|galactocerebroside sulfotransferase activity|galactosylceramide sulphotransferase activity|glycolipid sulfotransferase activity http://purl.obolibrary.org/obo/GO_0001733 CHEBI:23079 biolink:ChemicalSubstance cerebroside go-plus.json http://purl.obolibrary.org/obo/CHEBI_23079 UBERON:0000414 biolink:AnatomicalEntity mucous gland A gland in which the principal secretory cells are mucus secreting cells. go-plus.json mucous secreting gland|mucus-secreting gland|glandula mucosa|muciparous gland|mucus gland http://purl.obolibrary.org/obo/UBERON_0000414 UBERON:0000415 biolink:AnatomicalEntity artery wall An anatomical wall that is part of an artery [Automatically generated definition]. go-plus.json wall of artery|arterial wall http://purl.obolibrary.org/obo/UBERON_0000415 CHEBI:144711 biolink:ChemicalSubstance N-stearoyl-sphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_144711 chebi_ph7_3 CHEBI:144712 biolink:ChemicalSubstance N-(very-long-chain fatty acyl)-sphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_144712 chebi_ph7_3 CHEBI:23073 biolink:ChemicalSubstance glycopentaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23073 CHEBI:47040 biolink:ChemicalSubstance lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_47040 CHEBI:47041 biolink:ChemicalSubstance tetrahydroxytetrahydrofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_47041 CHEBI:47042 biolink:ChemicalSubstance hydroxycalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47042 CHEBI:23075 biolink:ChemicalSubstance glycotetraosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23075 CHEBI:62600 biolink:ChemicalSubstance 2-O-(alpha-D-glucopyranosyl)-3-O-phosphonato-D-glycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62600 chebi_ph7_3 CHEBI:62601 biolink:ChemicalSubstance 2-O-(alpha-D-glucopyranosyl)-3-O-phospho-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62601 CHEBI:62602 biolink:ChemicalSubstance 2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-O-phosphonato-D-glycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62602 chebi_ph7_3 CHEBI:62603 biolink:ChemicalSubstance 2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-O-phospho-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62603 GO:0001738 biolink:BiologicalProcess morphogenesis of a polarized epithelium The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis. go-plus.json epithelial polarization http://purl.obolibrary.org/obo/GO_0001738 CHEBI:144713 biolink:ChemicalSubstance N-(ultra-long-chain-acyl)-sphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_144713 chebi_ph7_3 CHEBI:62608 biolink:ChemicalSubstance EC 4.2.1.3 (aconitate hydratase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62608 GO:0001739 biolink:CellularComponent sex chromatin Chromatin that is part of a sex chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0001739 CHEBI:62609 biolink:ChemicalSubstance EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62609 GO:0001734 biolink:MolecularActivity mRNA (N6-adenosine)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U. Reactome:R-HSA-72095 go-plus.json http://purl.obolibrary.org/obo/GO_0001734 GO:0001735 biolink:MolecularActivity prenylcysteine oxidase activity Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2. MetaCyc:1.8.3.5-RXN|RHEA:53892|EC:1.8.3.5 go-plus.json prenylcysteine lyase activity|S-prenyl-L-cysteine:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0001735 GO:0001736 biolink:BiologicalProcess establishment of planar polarity Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates. go-plus.json establishment of planar cell polarity http://purl.obolibrary.org/obo/GO_0001736 GO:0001737 biolink:BiologicalProcess establishment of imaginal disc-derived wing hair orientation Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction. go-plus.json establishment of wing hair orientation http://purl.obolibrary.org/obo/GO_0001737 GO:0001741 biolink:CellularComponent XY body A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery. go-plus.json http://purl.obolibrary.org/obo/GO_0001741 UBERON:0000407 biolink:AnatomicalEntity sympathetic trunk One of a a paired bundle of nerve fibers plus ganglia that run from the base of the skull to the coccyx. go-plus.json truncus sympathicus|gangliated cord|sympathetic chain|sympathetic ganglionic chain http://purl.obolibrary.org/obo/UBERON_0000407 GO:0001742 biolink:BiologicalProcess oenocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. go-plus.json oenocyte cell differentiation http://purl.obolibrary.org/obo/GO_0001742 CHEBI:47037 biolink:ChemicalSubstance cyclic purine dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_47037 GO:0001743 biolink:BiologicalProcess lens placode formation The initial developmental process that will lead to the formation of an eye. go-plus.json optic placode formation http://purl.obolibrary.org/obo/GO_0001743 CHEBI:23089 biolink:ChemicalSubstance chelate-forming peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23089 GO:0001744 biolink:BiologicalProcess insect visual primordium formation Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system. go-plus.json optic lobe and Bolwig's organ precursor formation|optic lobe placode formation http://purl.obolibrary.org/obo/GO_0001744 CHEBI:47039 biolink:ChemicalSubstance 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47039 UBERON:0000409 biolink:AnatomicalEntity serous gland A gland in which the principal secretory cells are serous secreting cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000409 UBERON:0000402 biolink:AnatomicalEntity nasal vestibule The nasal vestibule is the most anterior part of the nasal cavity. It's enclosed by the cartilages of nose and lined by the same epithelium of the skin. The other part of the nasal cavity, which is lined by the respiratory epithelium, is called nasal cavity proper. [WP,unvetted]. go-plus.json vestibulum nasi|vestibulum nasale|vestibular part of nasal cavity http://purl.obolibrary.org/obo/UBERON_0000402 GO:0001740 biolink:CellularComponent Barr body A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery. Wikipedia:Barr_body|NIF_Subcellular:sao1571698684 go-plus.json http://purl.obolibrary.org/obo/GO_0001740 CHEBI:23084 biolink:ChemicalSubstance cetraxates go-plus.json http://purl.obolibrary.org/obo/CHEBI_23084 CHEBI:47031 biolink:ChemicalSubstance LL-2,6-diaminopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_47031 CHEBI:203600 biolink:ChemicalSubstance 1D-myo-inositol 1,4,5-trisphosphate(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_203600 chebi_ph7_3 CHEBI:23086 biolink:ChemicalSubstance chalcones go-plus.json http://purl.obolibrary.org/obo/CHEBI_23086 CHEBI:62611 biolink:ChemicalSubstance (S)-3-hydroxyisobutyryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62611 chebi_ph7_3 CHEBI:62612 biolink:ChemicalSubstance (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62612 chebi_ph7_3 CHEBI:62615 biolink:ChemicalSubstance 3-oxolauroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62615 chebi_ph7_3 CHEBI:62616 biolink:ChemicalSubstance (S)-3-hydroxydecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62616 chebi_ph7_3 CHEBI:62613 biolink:ChemicalSubstance (S)-3-hydroxypalmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62613 chebi_ph7_3 CHEBI:62614 biolink:ChemicalSubstance (S)-3-hydroxytetradecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62614 chebi_ph7_3 CHEBI:62619 biolink:ChemicalSubstance 3-oxooctanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62619 chebi_ph7_3 GO:0001749 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001749 UBERON:0000410 biolink:AnatomicalEntity bronchial mucosa A mucosa that is part of a bronchus [Automatically generated definition]. go-plus.json mucosa of bronchus|tunica mucosa bronchi|bronchial trunk organ mucosa|mucous membrane of bronchus|bronchi organ mucosa|bronchi mucosa of organ|organ mucosa of bronchi|organ mucosa of bronchial trunk|bronchial trunk mucosa of organ|bronchus mucosa of organ|bronchi mucous membrane|bronchial trunk mucous membrane|bronchus mucous membrane|bronchus mucosa|bronchial trunk mucosa|bronchi mucosa|organ mucosa of bronchus|mucous membrane of bronchi|mucosa of bronchi|mucous membrane of bronchial trunk|mucosa of bronchial trunk|mucosa of organ of bronchi|mucosa of organ of bronchial trunk|mucosa of organ of bronchus|bronchus organ mucosa http://purl.obolibrary.org/obo/UBERON_0000410 CHEBI:144703 biolink:ChemicalSubstance N-palmitoyl-sphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_144703 chebi_ph7_3 CHEBI:62617 biolink:ChemicalSubstance (S)-3-hydroxyoctanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62617 chebi_ph7_3 CHEBI:62618 biolink:ChemicalSubstance hydroxyacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_62618 GO:0001745 biolink:BiologicalProcess compound eye morphogenesis The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. go-plus.json insect-type retina morphogenesis http://purl.obolibrary.org/obo/GO_0001745 GO:0001746 biolink:BiologicalProcess Bolwig's organ morphogenesis The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain. go-plus.json http://purl.obolibrary.org/obo/GO_0001746 GO:0001747 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001747 GO:0001748 biolink:BiologicalProcess insect visual primordium development The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster. go-plus.json optic lobe and Bolwig's organ precursor development|optic placode development|optic lobe placode development http://purl.obolibrary.org/obo/GO_0001748 CHEBI:47025 biolink:ChemicalSubstance UDP-4-amino-4-deoxy-beta-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47025 CHEBI:47027 biolink:ChemicalSubstance UDP-4-deoxy-4-formamido-beta-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47027 GO:0001710 biolink:BiologicalProcess mesodermal cell fate commitment The cell differentiation process that results in commitment of a cell to become part of the mesoderm. go-plus.json mesoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0001710 CHEBI:47028 biolink:ChemicalSubstance UDP-beta-L-threo-pentopyranos-4-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47028 GO:0001711 biolink:BiologicalProcess endodermal cell fate commitment The cell differentiation process that results in commitment of a cell to become part of the endoderm. go-plus.json endoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0001711 CHEBI:47024 biolink:ChemicalSubstance aldehydo-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47024 CHEBI:23053 biolink:ChemicalSubstance catechin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23053 chebi_ph7_3 CHEBI:37699 biolink:ChemicalSubstance protein kinase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_37699 CHEBI:62622 biolink:ChemicalSubstance (5-hydroxyindol-3-yl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62622 chebi_ph7_3 CHEBI:62620 biolink:ChemicalSubstance hexanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62620 chebi_ph7_3 CHEBI:37697 biolink:ChemicalSubstance indolocarbazole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37697 CHEBI:62621 biolink:ChemicalSubstance L-selenomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62621 chebi_ph7_3 CHEBI:62626 biolink:ChemicalSubstance uroporphyrinogen I(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62626 chebi_ph7_3 CHEBI:62624 biolink:ChemicalSubstance 5-hydroxy-L-kynurenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62624 chebi_ph7_3 GO:0001716 biolink:MolecularActivity L-amino-acid oxidase activity Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide. Reactome:R-HSA-2160492|RHEA:13781|EC:1.4.3.2|MetaCyc:L-AMINO-ACID-OXIDASE-RXN go-plus.json L-amino-acid:oxygen oxidoreductase (deaminating)|ophio-amino-acid oxidase activity http://purl.obolibrary.org/obo/GO_0001716 GO:0001717 biolink:BiologicalProcess conversion of seryl-tRNAsec to selenocys-tRNAsec The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0001717 GO:0001718 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001718 GO:0001719 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001719 CHEBI:37690 biolink:ChemicalSubstance allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37690 GO:0001712 biolink:BiologicalProcess ectodermal cell fate commitment The cell differentiation process that results in commitment of a cell to become part of the ectoderm. go-plus.json ectoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0001712 GO:0001713 biolink:BiologicalProcess ectodermal cell fate determination The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json ectoderm cell fate determination http://purl.obolibrary.org/obo/GO_0001713 CHEBI:37696 biolink:ChemicalSubstance carbohydrate acid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_37696 GO:0001714 biolink:BiologicalProcess endodermal cell fate specification The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json endoderm cell fate specification http://purl.obolibrary.org/obo/GO_0001714 GO:0001715 biolink:BiologicalProcess ectodermal cell fate specification The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json ectoderm cell fate specification http://purl.obolibrary.org/obo/GO_0001715 CHEBI:37694 biolink:ChemicalSubstance O-phospho peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37694 CHEBI:47014 biolink:ChemicalSubstance aldehydo-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47014 chebi_ph7_3 CHEBI:47015 biolink:ChemicalSubstance aldehydo-L-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47015 chebi_ph7_3 GO:0001720 biolink:BiologicalProcess conversion of lysyl-tRNA to pyrrolysyl-tRNA The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate). go-plus.json http://purl.obolibrary.org/obo/GO_0001720 GO:0001721 biolink:CellularComponent obsolete intermediate filament associated protein OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks. go-plus.json intermediate filament associated protein|IFAP http://purl.obolibrary.org/obo/GO_0001721 CHEBI:47016 biolink:ChemicalSubstance tetrahydrofuranone go-plus.json http://purl.obolibrary.org/obo/CHEBI_47016 GO:0001722 biolink:CellularComponent obsolete type I intermediate filament associated protein OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates. go-plus.json type I intermediate filament associated protein http://purl.obolibrary.org/obo/GO_0001722 CHEBI:47017 biolink:ChemicalSubstance tetrahydrofuranol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47017 CHEBI:47018 biolink:ChemicalSubstance monohydroxytetrahydrofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_47018 CHEBI:47019 biolink:ChemicalSubstance dihydroxytetrahydrofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_47019 CHEBI:47010 biolink:ChemicalSubstance L-ribopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47010 chebi_ph7_3 CHEBI:23066 biolink:ChemicalSubstance cephalosporin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23066 CHEBI:47012 biolink:ChemicalSubstance beta-L-ribopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47012 chebi_ph7_3 CHEBI:47013 biolink:ChemicalSubstance D-ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47013 chebi_ph7_3 CHEBI:23064 biolink:ChemicalSubstance cephalosporanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23064 CHEBI:62631 biolink:ChemicalSubstance coproporphyrinogen I(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62631 chebi_ph7_3 CHEBI:62637 biolink:ChemicalSubstance L-4-hydroxyglutamate semialdehyde zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62637 chebi_ph7_3 CHEBI:62638 biolink:ChemicalSubstance (S)-3-hydroxyisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62638 chebi_ph7_3 GO:0001727 biolink:MolecularActivity lipid kinase activity Catalysis of the phosphorylation of a simple or complex lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0001727 GO:0001728 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001728 GO:0001729 biolink:MolecularActivity ceramide kinase activity Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate. RHEA:17929|Reactome:R-HSA-1638845|MetaCyc:CERAMIDE-KINASE-RXN|EC:2.7.1.138 go-plus.json ATP:ceramide 1-phosphotransferase activity|acylsphingosine kinase activity http://purl.obolibrary.org/obo/GO_0001729 CHEBI:62639 biolink:ChemicalSubstance 2-cis,6-trans,10-trans-geranylgeranyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62639 chebi_ph7_3 GO:0001723 biolink:CellularComponent obsolete type II intermediate filament associated protein OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks. go-plus.json type II intermediate filament associated protein http://purl.obolibrary.org/obo/GO_0001723 GO:0001724 biolink:CellularComponent obsolete type III intermediate filament associated protein OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane. go-plus.json type III intermediate filament associated protein http://purl.obolibrary.org/obo/GO_0001724 GO:0001725 biolink:CellularComponent stress fiber A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber. go-plus.json actin cable|stress fibre http://purl.obolibrary.org/obo/GO_0001725 GO:0001726 biolink:CellularComponent ruffle Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. go-plus.json membrane ruffle http://purl.obolibrary.org/obo/GO_0001726 GO:0050664 biolink:MolecularActivity oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule. EC:1.6.3.- go-plus.json oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor http://purl.obolibrary.org/obo/GO_0050664 GO:0050665 biolink:BiologicalProcess hydrogen peroxide biosynthetic process The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. go-plus.json hydrogen peroxide anabolism|H2O2 biosynthetic process|hydrogen peroxide synthesis|hydrogen peroxide formation|hydrogen peroxide generation|hydrogen peroxide biosynthesis http://purl.obolibrary.org/obo/GO_0050665 GO:0050662 biolink:MolecularActivity obsolete coenzyme binding OBSOLETE. Binding to a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. go-plus.json http://purl.obolibrary.org/obo/GO_0050662 GO:0050663 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050663 GO:1902418 biolink:BiologicalProcess (+)-abscisic acid D-glucopyranosyl ester transmembrane transport The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane. go-plus.json abscisic acid glucosyl ester transmembrane transport|ABA-GE transmembrane transport http://purl.obolibrary.org/obo/GO_1902418 GO:0050668 biolink:BiologicalProcess positive regulation of homocysteine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine. go-plus.json up regulation of homocysteine metabolic process|positive regulation of homocysteine metabolism|upregulation of homocysteine metabolic process|positive regulation of Hcy metabolic process|stimulation of homocysteine metabolic process|positive regulation of Hcy metabolism|activation of homocysteine metabolic process|up-regulation of homocysteine metabolic process http://purl.obolibrary.org/obo/GO_0050668 GO:1902419 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902419 GO:0050669 biolink:BiologicalProcess negative regulation of homocysteine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine. go-plus.json down-regulation of homocysteine metabolic process|downregulation of homocysteine metabolic process|negative regulation of homocysteine metabolism|down regulation of homocysteine metabolic process|inhibition of homocysteine metabolic process|negative regulation of Hcy metabolism|negative regulation of Hcy metabolic process http://purl.obolibrary.org/obo/GO_0050669 GO:1902416 biolink:BiologicalProcess positive regulation of mRNA binding Any process that activates or increases the frequency, rate or extent of mRNA binding. go-plus.json up regulation of mRNA binding|upregulation of mRNA binding|up-regulation of mRNA binding|activation of mRNA binding http://purl.obolibrary.org/obo/GO_1902416 GO:0050666 biolink:BiologicalProcess regulation of homocysteine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. go-plus.json regulation of Hcy metabolism|regulation of homocysteine metabolism|regulation of Hcy metabolic process http://purl.obolibrary.org/obo/GO_0050666 GO:1902417 biolink:MolecularActivity (+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other. go-plus.json ABA-GE transmembrane transporter activity|abscisic acid glucosyl ester transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902417 GO:0050667 biolink:BiologicalProcess homocysteine metabolic process The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine. go-plus.json homocysteine metabolism|Hcy metabolism|Hcy metabolic process http://purl.obolibrary.org/obo/GO_0050667 GO:1902414 biolink:BiologicalProcess protein localization to cell junction A process in which a protein is transported to, or maintained in, a location within a cell junction. go-plus.json protein localisation to cell junction|protein localization in cell junction|protein localisation in cell junction http://purl.obolibrary.org/obo/GO_1902414 GO:1902415 biolink:BiologicalProcess regulation of mRNA binding Any process that modulates the frequency, rate or extent of mRNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_1902415 GO:1902412 biolink:BiologicalProcess regulation of mitotic cytokinesis Any process that modulates the frequency, rate or extent of mitotic cytokinesis. go-plus.json regulation of cytokinesis after mitosis http://purl.obolibrary.org/obo/GO_1902412 GO:1902413 biolink:BiologicalProcess negative regulation of mitotic cytokinesis Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis. go-plus.json inhibition of cytokinesis after mitosis|down-regulation of mitotic cytokinesis|inhibition of mitotic cytokinesis|down regulation of cytokinesis after mitosis|downregulation of cytokinesis after mitosis|down regulation of mitotic cytokinesis|down-regulation of cytokinesis after mitosis|negative regulation of cytokinesis after mitosis|downregulation of mitotic cytokinesis http://purl.obolibrary.org/obo/GO_1902413 GO:1902410 biolink:BiologicalProcess mitotic cytokinetic process Any cytokinetic process that is involved in mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1902410 GO:1902411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902411 GO:0035023 biolink:BiologicalProcess regulation of Rho protein signal transduction Any process that modulates the frequency, rate or extent of Rho protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0035023 GO:0035024 biolink:BiologicalProcess negative regulation of Rho protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction. go-plus.json down regulation of Rho protein signal transduction|downregulation of Rho protein signal transduction|down-regulation of Rho protein signal transduction|inhibition of Rho protein signal transduction http://purl.obolibrary.org/obo/GO_0035024 GO:0035025 biolink:BiologicalProcess positive regulation of Rho protein signal transduction Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction. go-plus.json upregulation of Rho protein signal transduction|up regulation of Rho protein signal transduction|activation of Rho protein signal transduction|stimulation of Rho protein signal transduction|up-regulation of Rho protein signal transduction http://purl.obolibrary.org/obo/GO_0035025 GO:0035026 biolink:BiologicalProcess leading edge cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0035026 NCBITaxon:311400 biolink:OrganismalEntity Thermococcus kodakarensis go-plus.json Pyrococcus kodakaraensis|Thermococcus kodakaraensis|Pyrococcus kodadaraensis (sic) http://purl.obolibrary.org/obo/NCBITaxon_311400 GO:0035027 biolink:BiologicalProcess leading edge cell fate commitment The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0035027 GO:0035028 biolink:BiologicalProcess leading edge cell fate determination The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0035028 GO:0098608 biolink:MolecularActivity methylselenol demethylase activity Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH. Reactome:R-HSA-2408530 go-plus.json http://purl.obolibrary.org/obo/GO_0098608 GO:0035029 biolink:BiologicalProcess dorsal closure, leading edge cell fate commitment The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0035029 GO:0098609 biolink:BiologicalProcess cell-cell adhesion The attachment of one cell to another cell via adhesion molecules. go-plus.json single organismal cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 GO:0098606 biolink:MolecularActivity selenocystathionine gamma-lyase activity Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid. Reactome:R-HSA-2408543|RHEA:31151 go-plus.json http://purl.obolibrary.org/obo/GO_0098606 GO:0098607 biolink:MolecularActivity methylselenocysteine deselenhydrase activity Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol. Reactome:R-HSA-2408539 go-plus.json http://purl.obolibrary.org/obo/GO_0098607 GO:0098604 biolink:MolecularActivity adenosylselenohomocysteinase activity Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine. Reactome:R-HSA-2408532 go-plus.json http://purl.obolibrary.org/obo/GO_0098604 GO:0098605 biolink:MolecularActivity selenocystathionine beta-synthase activity Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O. Reactome:R-HSA-2408559 go-plus.json http://purl.obolibrary.org/obo/GO_0098605 GO:0050660 biolink:MolecularActivity flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. go-plus.json FAD or FADH2 binding|flavine-adenine dinucleotide binding http://purl.obolibrary.org/obo/GO_0050660 GO:0098602 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098602 GO:0098603 biolink:MolecularActivity selenol Se-methyltransferase activity Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine. Reactome:R-HSA-2408544 go-plus.json http://purl.obolibrary.org/obo/GO_0098603 GO:0050661 biolink:MolecularActivity NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. go-plus.json nicotinamide adenine dinucleotide phosphate binding|NADP or NADPH binding|NADP+ or NADPH binding http://purl.obolibrary.org/obo/GO_0050661 GO:0035020 biolink:BiologicalProcess regulation of Rac protein signal transduction Any process that modulates the frequency, rate or extent of Rac protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0035020 GO:0098600 biolink:MolecularActivity selenomethionine gamma-lyase activity Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid. Reactome:R-HSA-2408537 go-plus.json http://purl.obolibrary.org/obo/GO_0098600 GO:0035021 biolink:BiologicalProcess negative regulation of Rac protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction. go-plus.json down regulation of Rac protein signal transduction|downregulation of Rac protein signal transduction|down-regulation of Rac protein signal transduction|inhibition of Rac protein signal transduction http://purl.obolibrary.org/obo/GO_0035021 GO:0035022 biolink:BiologicalProcess positive regulation of Rac protein signal transduction Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction. go-plus.json upregulation of Rac protein signal transduction|up regulation of Rac protein signal transduction|activation of Rac protein signal transduction|stimulation of Rac protein signal transduction|up-regulation of Rac protein signal transduction http://purl.obolibrary.org/obo/GO_0035022 GO:0098601 biolink:MolecularActivity selenomethionine adenosyltransferase activity Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine. Reactome:R-HSA-2408551|RHEA:31211 go-plus.json http://purl.obolibrary.org/obo/GO_0098601 GO:0050675 biolink:BiologicalProcess regulation of urothelial cell proliferation Any process that modulates the frequency, rate or extent of urothelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0050675 GO:0098610 biolink:BiologicalProcess adhesion between unicellular organisms The attachment of two unicellular organisms to each other. go-plus.json multi-organismal cell-cell adhesion|adhesion between unicellular organisms via cell-wall interaction http://purl.obolibrary.org/obo/GO_0098610 GO:0050676 biolink:BiologicalProcess negative regulation of urothelial cell proliferation Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation. go-plus.json down-regulation of urothelial cell proliferation|inhibition of urothelial cell proliferation|down regulation of urothelial cell proliferation|downregulation of urothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050676 GO:0050673 biolink:BiologicalProcess epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. go-plus.json http://purl.obolibrary.org/obo/GO_0050673 GO:0050674 biolink:BiologicalProcess urothelial cell proliferation The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. go-plus.json http://purl.obolibrary.org/obo/GO_0050674 GO:0050679 biolink:BiologicalProcess positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. go-plus.json up-regulation of epithelial cell proliferation|upregulation of epithelial cell proliferation|up regulation of epithelial cell proliferation|activation of epithelial cell proliferation|stimulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050679 GO:1902429 biolink:BiologicalProcess positive regulation of water channel activity Any process that activates or increases the frequency, rate or extent of water channel activity. go-plus.json upregulation of water channel activity|activation of aquaporin|up-regulation of aquaporin|up-regulation of water channel activity|activation of water channel activity|aquaporin activation|upregulation of aquaporin|up regulation of water channel activity|up regulation of aquaporin|positive regulation of aquaporin http://purl.obolibrary.org/obo/GO_1902429 GO:0050677 biolink:BiologicalProcess positive regulation of urothelial cell proliferation Any process that activates or increases the rate or extent of urothelial cell proliferation. go-plus.json up regulation of urothelial cell proliferation|activation of urothelial cell proliferation|stimulation of urothelial cell proliferation|up-regulation of urothelial cell proliferation|upregulation of urothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050677 GO:1902427 biolink:BiologicalProcess regulation of water channel activity Any process that modulates the frequency, rate or extent of water channel activity. go-plus.json regulation of aquaporin|regulation of aquaporin permeability http://purl.obolibrary.org/obo/GO_1902427 GO:1902428 biolink:BiologicalProcess negative regulation of water channel activity Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity. go-plus.json down regulation of water channel activity|inhibition of water channel activity|negative regulation of aquaporin|down-regulation of aquaporin|inhibition of aquaporin|down-regulation of water channel activity|down regulation of aquaporin|downregulation of aquaporin|downregulation of water channel activity http://purl.obolibrary.org/obo/GO_1902428 GO:0050678 biolink:BiologicalProcess regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0050678 GO:1902425 biolink:BiologicalProcess positive regulation of attachment of mitotic spindle microtubules to kinetochore Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation. go-plus.json up regulation of attachment of spindle microtubules to kinetochore involved in mitosis|up regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|activation of attachment of spindle microtubules to kinetochore involved in mitosis|upregulation of mitotic bipolar attachment|positive regulation of attachment of spindle microtubules to kinetochore involved in mitosis|up-regulation of attachment of spindle microtubules to mitotic chromosome|activation of attachment of spindle microtubules to mitotic chromosome|upregulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of mitotic bipolar attachment|up-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|positive regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|positive regulation of attachment of spindle microtubules to mitotic chromosome|up-regulation of attachment of spindle microtubules to kinetochore during mitosis|up regulation of attachment of spindle microtubules to mitotic chromosome|activation of mitotic bipolar attachment|activation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|activation of attachment of spindle microtubules to kinetochore during mitosis|positive regulation of mitotic bipolar attachment|upregulation of attachment of spindle microtubules to kinetochore involved in mitosis|up regulation of mitotic bipolar attachment|positive regulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of attachment of spindle microtubules to mitotic chromosome|up regulation of attachment of spindle microtubules to kinetochore during mitosis http://purl.obolibrary.org/obo/GO_1902425 GO:1902426 biolink:BiologicalProcess deactivation of mitotic spindle assembly checkpoint A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint. go-plus.json inhibition of Mad2-dependent checkpoint|inhibition of mitotic spindle assembly checkpoint|mitotic spindle assembly checkpoint silencing|negative regulation of mitotic cell cycle spindle assembly checkpoint|down-regulation of mitotic cell cycle spindle assembly checkpoint|down regulation of Mad2-dependent checkpoint|negative regulation of mitotic spindle assembly checkpoint|downregulation of Mad2-dependent checkpoint|down regulation of mitotic spindle assembly checkpoint|downregulation of mitotic cell cycle spindle assembly checkpoint|down regulation of mitotic cell cycle spindle assembly checkpoint|downregulation of mitotic spindle assembly checkpoint|inhibition of mitotic cell cycle spindle assembly checkpoint|mitotic spindle assembly deactivation|negative regulation of Mad2-dependent checkpoint|down-regulation of Mad2-dependent checkpoint|down-regulation of mitotic spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_1902426 GO:1902423 biolink:BiologicalProcess regulation of attachment of mitotic spindle microtubules to kinetochore Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation. go-plus.json regulation of mitotic bipolar attachment|regulation of attachment of spindle microtubules to kinetochore during mitosis|regulation of attachment of spindle microtubules to mitotic chromosome|regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|regulation of mitotic attachment of spindle microtubules to kinetochore|regulation of attachment of spindle microtubules to kinetochore involved in mitosis http://purl.obolibrary.org/obo/GO_1902423 GO:1902424 biolink:BiologicalProcess negative regulation of attachment of mitotic spindle microtubules to kinetochore Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation. go-plus.json downregulation of attachment of spindle microtubules to kinetochore involved in mitosis|downregulation of attachment of spindle microtubules to kinetochore during mitosis|down regulation of mitotic bipolar attachment|down regulation of attachment of spindle microtubules to kinetochore during mitosis|downregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|negative regulation of mitotic attachment of spindle microtubules to kinetochore|negative regulation of attachment of spindle microtubules to kinetochore involved in mitosis|down-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|inhibition of mitotic bipolar attachment|down regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore during mitosis|down-regulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore involved in mitosis|downregulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of mitotic bipolar attachment|down-regulation of mitotic bipolar attachment|negative regulation of attachment of spindle microtubules to kinetochore during mitosis|down-regulation of attachment of spindle microtubules to kinetochore during mitosis|down regulation of attachment of spindle microtubules to mitotic chromosome|down regulation of attachment of spindle microtubules to kinetochore involved in mitosis|inhibition of attachment of spindle microtubules to mitotic chromosome|down-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|downregulation of mitotic bipolar attachment http://purl.obolibrary.org/obo/GO_1902424 GO:1902421 biolink:BiologicalProcess hydrogen metabolic process The chemical reactions and pathways involving H2 (dihydrogen). go-plus.json H2 metabolism|molecular hydrogen metabolism|dihydrogen metabolism http://purl.obolibrary.org/obo/GO_1902421 GO:1902422 biolink:BiologicalProcess hydrogen biosynthetic process The chemical reactions and pathways resulting in the formation of H2 (dihydrogen). go-plus.json dihydrogen synthesis|hydrogen anabolism|hydrogen generation|hydrogen synthesis|hydrogen formation|H2 biosynthesis|hydrogen biosynthesis|molecular hydrogen biosynthesis|hydrogen production http://purl.obolibrary.org/obo/GO_1902422 GO:1902420 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902420 GO:0035012 biolink:CellularComponent obsolete polytene chromosome, telomeric region OBSOLETE. The terminal region of a polytene chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0035012 GO:0035013 biolink:MolecularActivity myosuppressin receptor activity Combining with the peptide myosuppressin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035013 GO:0035014 biolink:MolecularActivity phosphatidylinositol 3-kinase regulator activity Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates. go-plus.json phosphoinositide 3-kinase regulator activity|PI3K regulator activity http://purl.obolibrary.org/obo/GO_0035014 GO:0035015 biolink:BiologicalProcess elongation of arista core The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions. go-plus.json http://purl.obolibrary.org/obo/GO_0035015 GO:0035016 biolink:BiologicalProcess elongation of arista lateral The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions. go-plus.json http://purl.obolibrary.org/obo/GO_0035016 GO:0035017 biolink:BiologicalProcess cuticle pattern formation The regionalization process that gives rise to the patterns of cell differentiation in the cuticle. go-plus.json http://purl.obolibrary.org/obo/GO_0035017 GO:0098619 biolink:MolecularActivity selenocysteine-tRNA ligase activity Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate. Reactome:R-HSA-2408526 go-plus.json http://purl.obolibrary.org/obo/GO_0098619 GO:0035018 biolink:BiologicalProcess adult chitin-based cuticle pattern formation The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster. go-plus.json adult cuticle pattern formation http://purl.obolibrary.org/obo/GO_0035018 GO:0035019 biolink:BiologicalProcess somatic stem cell population maintenance Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. go-plus.json http://purl.obolibrary.org/obo/GO_0035019 GO:0098617 biolink:MolecularActivity adenylylselenate kinase activity Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate. Reactome:R-HSA-2408540 go-plus.json http://purl.obolibrary.org/obo/GO_0098617 GO:0098618 biolink:MolecularActivity selenomethionine-tRNA ligase activity Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met). Reactome:R-HSA-2408546 go-plus.json http://purl.obolibrary.org/obo/GO_0098618 GO:0098615 biolink:MolecularActivity dimethyl selenide methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium. Reactome:R-HSA-2408554 go-plus.json http://purl.obolibrary.org/obo/GO_0098615 GO:0098616 biolink:MolecularActivity selenate adenylyltransferase (ATP) activity Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate. Reactome:R-HSA-2408525 go-plus.json http://purl.obolibrary.org/obo/GO_0098616 GO:0098613 biolink:MolecularActivity methaneselenol methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide. Reactome:R-HSA-2408541 go-plus.json http://purl.obolibrary.org/obo/GO_0098613 GO:0050671 biolink:BiologicalProcess positive regulation of lymphocyte proliferation Any process that activates or increases the rate or extent of lymphocyte proliferation. go-plus.json up regulation of lymphocyte proliferation|upregulation of lymphocyte proliferation|stimulation of lymphocyte proliferation|up-regulation of lymphocyte proliferation|activation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0050671 GO:0098614 biolink:MolecularActivity hydrogen selenide methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol. Reactome:R-HSA-2408536 go-plus.json http://purl.obolibrary.org/obo/GO_0098614 GO:0050672 biolink:BiologicalProcess negative regulation of lymphocyte proliferation Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. go-plus.json down-regulation of lymphocyte proliferation|downregulation of lymphocyte proliferation|down regulation of lymphocyte proliferation|inhibition of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0050672 GO:0035010 biolink:BiologicalProcess encapsulation of foreign target Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization. go-plus.json http://purl.obolibrary.org/obo/GO_0035010 GO:0098611 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098611 GO:0035011 biolink:BiologicalProcess melanotic encapsulation of foreign target Formation of a multilayered, melanized sheath of cells around a foreign invader. go-plus.json http://purl.obolibrary.org/obo/GO_0035011 GO:0098612 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098612 GO:0050670 biolink:BiologicalProcess regulation of lymphocyte proliferation Any process that modulates the frequency, rate or extent of lymphocyte proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0050670 GO:0050686 biolink:BiologicalProcess negative regulation of mRNA processing Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing. go-plus.json inhibition of mRNA processing|down regulation of mRNA processing|downregulation of mRNA processing|down-regulation of mRNA processing http://purl.obolibrary.org/obo/GO_0050686 GO:0050687 biolink:BiologicalProcess negative regulation of defense response to virus Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication. go-plus.json down-regulation of antiviral response|downregulation of antiviral response|negative regulation of antiviral response|down regulation of antiviral response|inhibition of antiviral response http://purl.obolibrary.org/obo/GO_0050687 GO:0050684 biolink:BiologicalProcess regulation of mRNA processing Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0050684 GO:0050685 biolink:BiologicalProcess positive regulation of mRNA processing Any process that activates or increases the frequency, rate or extent of mRNA processing. go-plus.json up-regulation of mRNA processing|upregulation of mRNA processing|up regulation of mRNA processing|activation of mRNA processing|stimulation of mRNA processing http://purl.obolibrary.org/obo/GO_0050685 GO:1902438 biolink:BiologicalProcess response to vanadate(3-) Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902438 GO:0050688 biolink:BiologicalProcess regulation of defense response to virus Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism. go-plus.json regulation of antiviral response http://purl.obolibrary.org/obo/GO_0050688 GO:1902439 biolink:BiologicalProcess cellular response to vanadate(3-) Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902439 GO:0050689 biolink:BiologicalProcess negative regulation of defense response to virus by host Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json down regulation of antiviral response by host|inhibition of antiviral response by host|negative regulation of antiviral response by host|down-regulation of antiviral response by host|negative regulation by host of antiviral response|downregulation of antiviral response by host http://purl.obolibrary.org/obo/GO_0050689 GO:1902436 biolink:BiologicalProcess negative regulation of male mating behavior Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior. go-plus.json downregulation of male mating behavior|down regulation of male mating behavior|inhibition of male mating behavior|down-regulation of male mating behavior http://purl.obolibrary.org/obo/GO_1902436 GO:0035009 biolink:BiologicalProcess negative regulation of melanization defense response Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection. go-plus.json downregulation of melanization defense response|down-regulation of melanization defense response|inhibition of melanization defense response|negative regulation of melanization defence response|down regulation of melanization defense response http://purl.obolibrary.org/obo/GO_0035009 GO:1902437 biolink:BiologicalProcess positive regulation of male mating behavior Any process that activates or increases the frequency, rate or extent of male mating behavior. go-plus.json upregulation of male mating behavior|activation of male mating behavior|up-regulation of male mating behavior|up regulation of male mating behavior http://purl.obolibrary.org/obo/GO_1902437 GO:1902434 biolink:BiologicalProcess sulfate import across plasma membrane The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json sulphate import into cell|sulfate import into cell http://purl.obolibrary.org/obo/GO_1902434 GO:1902435 biolink:BiologicalProcess regulation of male mating behavior Any process that modulates the frequency, rate or extent of male mating behavior. go-plus.json http://purl.obolibrary.org/obo/GO_1902435 GO:1902432 biolink:BiologicalProcess protein localization to division septum A process in which a protein is transported to, or maintained in, a location within a division septum. go-plus.json protein localization in division septum|protein localisation in division septum|protein localisation to division septum http://purl.obolibrary.org/obo/GO_1902432 GO:1902433 biolink:BiologicalProcess positive regulation of water channel activity involved in maintenance of lens transparency Any positive regulation of water channel activity that is involved in maintenance of lens transparency. go-plus.json activation of water channel activity involved in maintenance of lens transparency|up-regulation of aquaporin involved in preservation of lens transparency|aquaporin activation involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in maintenance of lens transparency|up-regulation of aquaporin involved in maintenance of ocular lens transparency|activation of water channel activity involved in preservation of lens transparency|up-regulation of water channel activity involved in preservation of lens transparency|aquaporin activation involved in maintenance of lens transparency|activation of water channel activity involved in maintenance of ocular lens transparency|up-regulation of water channel activity involved in maintenance of ocular lens transparency|activation of aquaporin involved in maintenance of lens transparency|upregulation of aquaporin involved in preservation of lens transparency|up-regulation of water channel activity involved in maintenance of lens transparency|upregulation of aquaporin involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in maintenance of lens transparency|positive regulation of water channel activity involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of lens transparency|up regulation of water channel activity involved in preservation of lens transparency|positive regulation of water channel activity involved in maintenance of ocular lens transparency|up regulation of aquaporin involved in preservation of lens transparency|upregulation of water channel activity involved in maintenance of lens transparency|up regulation of water channel activity involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in maintenance of ocular lens transparency|upregulation of aquaporin involved in maintenance of lens transparency|upregulation of water channel activity involved in preservation of lens transparency|activation of aquaporin involved in preservation of lens transparency|activation of aquaporin involved in maintenance of ocular lens transparency|up regulation of water channel activity involved in maintenance of lens transparency|aquaporin activation involved in preservation of lens transparency|upregulation of water channel activity involved in maintenance of ocular lens transparency http://purl.obolibrary.org/obo/GO_1902433 GO:1902430 biolink:BiologicalProcess negative regulation of amyloid-beta formation Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation. go-plus.json down regulation of beta-amyloid formation|inhibition of beta-amyloid formation|negative regulation of beta-amyloid formation|down-regulation of beta-amyloid formation|downregulation of beta-amyloid formation http://purl.obolibrary.org/obo/GO_1902430 GO:0060010 biolink:BiologicalProcess Sertoli cell fate commitment The process in which the cellular identity of Sertoli cells is acquired and determined. go-plus.json http://purl.obolibrary.org/obo/GO_0060010 GO:1902431 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902431 GO:0060011 biolink:BiologicalProcess Sertoli cell proliferation The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0060011 GO:0035001 biolink:BiologicalProcess dorsal trunk growth, open tracheal system Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system. go-plus.json dorsal trunk growth http://purl.obolibrary.org/obo/GO_0035001 GO:0060012 biolink:BiologicalProcess synaptic transmission, glycinergic The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json glycinergic synaptic transmission http://purl.obolibrary.org/obo/GO_0060012 GO:1902440 biolink:BiologicalProcess protein localization to mitotic spindle pole body A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body. go-plus.json protein localisation to mitotic spindle pole body|establishment of protein localization to mitotic spindle pole body|protein localization in mitotic spindle pole body|protein localisation in mitotic spindle pole body http://purl.obolibrary.org/obo/GO_1902440 GO:0060013 biolink:BiologicalProcess righting reflex A reflex process in which an animal immediately tries to turn over after being placed in a supine position. go-plus.json righting response http://purl.obolibrary.org/obo/GO_0060013 GO:0035002 biolink:BiologicalProcess liquid clearance, open tracheal system The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system. go-plus.json tracheal liquid clearance http://purl.obolibrary.org/obo/GO_0035002 GO:0035003 biolink:CellularComponent subapical complex The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells. go-plus.json SAC http://purl.obolibrary.org/obo/GO_0035003 GO:0060014 biolink:BiologicalProcess granulosa cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0060014 GO:0035004 biolink:MolecularActivity phosphatidylinositol 3-kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring. Reactome:R-HSA-9670433|Reactome:R-HSA-9028519|Wikipedia:Phosphoinositide_3-kinase|Reactome:R-HSA-1433514|Reactome:R-HSA-2045911 go-plus.json phosphoinositide 3-kinase activity http://purl.obolibrary.org/obo/GO_0035004 GO:0060015 biolink:BiologicalProcess granulosa cell fate commitment The cell fate commitment of precursor cells that will become granulosa cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060015 GO:0035005 biolink:MolecularActivity 1-phosphatidylinositol-4-phosphate 3-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+). MetaCyc:2.7.1.154-RXN|KEGG_REACTION:R05795|EC:2.7.1.154|RHEA:18373|Reactome:R-HSA-1676206|Reactome:R-HSA-1676109|Reactome:R-HSA-8868072|Reactome:R-HSA-1675928 go-plus.json C2-domain-containing phosphoinositide 3-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase activity, class II|phosphatidylinositol 3-kinase, class I, catalyst activity|phosphatidylinositol-4-phosphate 3-kinase activity|type II phosphoinositide 3-kinase activity http://purl.obolibrary.org/obo/GO_0035005 GO:0060016 biolink:BiologicalProcess granulosa cell development The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060016 GO:0060017 biolink:BiologicalProcess parathyroid gland development The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0060017 GO:0035006 biolink:BiologicalProcess melanization defense response The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin. go-plus.json melanization defence response http://purl.obolibrary.org/obo/GO_0035006 GO:0035007 biolink:BiologicalProcess regulation of melanization defense response Any process that affects the rate, extent or location of the melanization defense response during injury or invasion. go-plus.json regulation of melanization defence response http://purl.obolibrary.org/obo/GO_0035007 GO:0060018 biolink:BiologicalProcess astrocyte fate commitment The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0060018 GO:0035008 biolink:BiologicalProcess positive regulation of melanization defense response Any process that increases the rate or extent of the melanization defense response during injury or invasion. go-plus.json up regulation of melanization defense response|activation of melanization defense response|stimulation of melanization defense response|up-regulation of melanization defense response|positive regulation of melanization defence response|upregulation of melanization defense response http://purl.obolibrary.org/obo/GO_0035008 GO:0060019 biolink:BiologicalProcess radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060019 GO:0050682 biolink:MolecularActivity AF-2 domain binding Binding to an AF-2 protein domain, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation. go-plus.json http://purl.obolibrary.org/obo/GO_0050682 GO:0050683 biolink:MolecularActivity AF-1 domain binding Binding to an AF-1 protein domain, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0050683 GO:0050680 biolink:BiologicalProcess negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. go-plus.json down-regulation of epithelial cell proliferation|inhibition of epithelial cell proliferation|down regulation of epithelial cell proliferation|downregulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050680 GO:0035000 biolink:CellularComponent oligosaccharyltransferase III complex An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes. go-plus.json OSTCIII http://purl.obolibrary.org/obo/GO_0035000 GO:0050681 biolink:MolecularActivity androgen receptor binding Binding to an androgen receptor. go-plus.json AR binding http://purl.obolibrary.org/obo/GO_0050681 GO:0050697 biolink:MolecularActivity 1,1,2-trichloroethene reductive dehalogenase activity Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene. MetaCyc:TCEREDCHLOR-RXN|UM-BBD_enzymeID:e0271 go-plus.json 1,1,2-trichloroethylene reductive dehalogenase activity|TCE-reductive dehalogenase activity http://purl.obolibrary.org/obo/GO_0050697 GO:0050698 biolink:MolecularActivity proteoglycan sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans. go-plus.json proteoglycan sulphotransferase activity|proteoglycan sulfate transfer http://purl.obolibrary.org/obo/GO_0050698 GO:0050695 biolink:MolecularActivity benzoylformate decarboxylase activity Catalysis of the reaction: benzoylformate = benzaldehyde + CO2. EC:4.1.1.7|MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN|UM-BBD_reactionID:r1049|RHEA:23368 go-plus.json benzoylformate carboxy-lyase activity|benzoylformate carboxy-lyase (benzaldehyde-forming)|phenylglyoxylate decarboxylase activity http://purl.obolibrary.org/obo/GO_0050695 GO:0050696 biolink:BiologicalProcess trichloroethylene catabolic process The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent. go-plus.json trichloroethylene degradation|trichloroethylene breakdown|trichloroethene catabolism|trichloroethene catabolic process|trichloroethylene catabolism http://purl.obolibrary.org/obo/GO_0050696 GO:0050699 biolink:MolecularActivity WW domain binding Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions. go-plus.json http://purl.obolibrary.org/obo/GO_0050699 GO:1902449 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902449 GO:1902447 biolink:BiologicalProcess negative regulation of shade avoidance Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance. go-plus.json down regulation of shade avoidance|downregulation of shade avoidance|down-regulation of shade avoidance|inhibition of shade avoidance http://purl.obolibrary.org/obo/GO_1902447 GO:1902448 biolink:BiologicalProcess positive regulation of shade avoidance Any process that activates or increases the frequency, rate or extent of shade avoidance. go-plus.json up regulation of shade avoidance|activation of shade avoidance|up-regulation of shade avoidance|upregulation of shade avoidance http://purl.obolibrary.org/obo/GO_1902448 GO:1902445 biolink:BiologicalProcess regulation of mitochondrial membrane permeability involved in programmed necrotic cell death Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death. go-plus.json regulation of transport across mitochondrial membrane involved in programmed necrotic cell death http://purl.obolibrary.org/obo/GO_1902445 GO:1902446 biolink:BiologicalProcess regulation of shade avoidance Any process that modulates the frequency, rate or extent of shade avoidance. go-plus.json http://purl.obolibrary.org/obo/GO_1902446 GO:1902443 biolink:BiologicalProcess negative regulation of ripoptosome assembly involved in necroptotic process Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process. go-plus.json down-regulation of ripoptosome assembly involved in necroptosis|downregulation of ripoptosome assembly involved in necroptosis|negative regulation of ripoptosome assembly involved in necroptosis|down regulation of ripoptosome assembly involved in necroptosis|inhibition of ripoptosome assembly involved in necroptosis http://purl.obolibrary.org/obo/GO_1902443 GO:1902444 biolink:MolecularActivity riboflavin binding Binding to riboflavin. go-plus.json http://purl.obolibrary.org/obo/GO_1902444 GO:1902441 biolink:BiologicalProcess protein localization to meiotic spindle pole body A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body. go-plus.json protein localisation in meiotic spindle pole body|protein localisation to meiotic spindle pole body|establishment of protein localization to meiotic spindle pole body|protein location to meiotic spindle pole body|protein localization in meiotic spindle pole body http://purl.obolibrary.org/obo/GO_1902441 GO:1902442 biolink:BiologicalProcess regulation of ripoptosome assembly involved in necroptotic process Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process. go-plus.json regulation of ripoptosome assembly involved in necroptosis http://purl.obolibrary.org/obo/GO_1902442 GO:0060001 biolink:MolecularActivity minus-end directed microfilament motor activity A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers. go-plus.json minus-end directed actin-filament motor activity|minus-end directed actin filament motor activity|pointed-end directed actin-filament motor activity http://purl.obolibrary.org/obo/GO_0060001 GO:1902450 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902450 GO:0060002 biolink:MolecularActivity plus-end directed microfilament motor activity A motor activity that generates movement along a microfilament towards the plus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers. go-plus.json plus-end directed actin filament motor activity|plus-end directed actin-filament motor activity|barbed-end directed actin-filament motor activity http://purl.obolibrary.org/obo/GO_0060002 GO:1902451 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902451 GO:0060003 biolink:BiologicalProcess copper ion export The directed movement of copper ions out of a cell or organelle. go-plus.json copper export http://purl.obolibrary.org/obo/GO_0060003 GO:0060004 biolink:BiologicalProcess reflex An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness. Wikipedia:Reflex go-plus.json http://purl.obolibrary.org/obo/GO_0060004 GO:0060005 biolink:BiologicalProcess vestibular reflex A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. go-plus.json http://purl.obolibrary.org/obo/GO_0060005 GO:0060006 biolink:BiologicalProcess angular vestibuloocular reflex A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. go-plus.json http://purl.obolibrary.org/obo/GO_0060006 GO:0060007 biolink:BiologicalProcess linear vestibuloocular reflex A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. go-plus.json http://purl.obolibrary.org/obo/GO_0060007 GO:0060008 biolink:BiologicalProcess Sertoli cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0060008 GO:0060009 biolink:BiologicalProcess Sertoli cell development The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060009 GO:0050690 biolink:BiologicalProcess regulation of defense response to virus by virus Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism. go-plus.json viral regulation of antiviral response|regulation of antiviral response by virus|regulation by virus of antiviral response http://purl.obolibrary.org/obo/GO_0050690 GO:0050693 biolink:MolecularActivity LBD domain binding Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket. go-plus.json ligand binding domain binding http://purl.obolibrary.org/obo/GO_0050693 GO:0050694 biolink:MolecularActivity galactose 3-O-sulfotransferase activity Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc. go-plus.json Gal-3-O-sulfotransferase activity|galactose 3-O-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0050694 GO:0050691 biolink:BiologicalProcess regulation of defense response to virus by host Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism. go-plus.json host regulation of antiviral response|regulation by host of antiviral response|regulation of antiviral response by host http://purl.obolibrary.org/obo/GO_0050691 GO:0050692 biolink:MolecularActivity DNA binding domain binding Binding to a protein's DNA binding domain (DBD). go-plus.json DBD binding http://purl.obolibrary.org/obo/GO_0050692 GO:0098642 biolink:CellularComponent network-forming collagen trimer A collagen trimer that forms networks. go-plus.json http://purl.obolibrary.org/obo/GO_0098642 GO:0001697 biolink:BiologicalProcess histamine-induced gastric acid secretion The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP. go-plus.json http://purl.obolibrary.org/obo/GO_0001697 GO:0001698 biolink:BiologicalProcess gastrin-induced gastric acid secretion The regulated release of gastric acid induced by the interaction of gastrin with its receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0001698 GO:0098643 biolink:CellularComponent banded collagen fibril A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). go-plus.json http://purl.obolibrary.org/obo/GO_0098643 GO:0098640 biolink:MolecularActivity integrin binding involved in cell-matrix adhesion Any integrin binding that occurs as part of the process of cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0098640 GO:0001699 biolink:BiologicalProcess acetylcholine-induced gastric acid secretion The regulated release of gastric acid by parietal cells in response to acetylcholine. go-plus.json http://purl.obolibrary.org/obo/GO_0001699 GO:0098641 biolink:MolecularActivity cadherin binding involved in cell-cell adhesion Any cadherin binding that occurs as part of the process of cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0098641 GO:0001693 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001693 GO:0001694 biolink:BiologicalProcess histamine biosynthetic process The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json histamine anabolism|histamine synthesis|histamine formation|histamine biosynthesis http://purl.obolibrary.org/obo/GO_0001694 GO:0001695 biolink:BiologicalProcess histamine catabolic process The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json histamine catabolism|histamine degradation|histamine breakdown http://purl.obolibrary.org/obo/GO_0001695 GO:0001696 biolink:BiologicalProcess gastric acid secretion The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. go-plus.json hydrochloric acid secretion http://purl.obolibrary.org/obo/GO_0001696 GO:1902458 biolink:BiologicalProcess positive regulation of stomatal opening Any process that activates or increases the frequency, rate or extent of stomatal opening. go-plus.json up regulation of stomatal opening|upregulation of stomatal opening|up-regulation of stomatal opening|activation of stomatal opening http://purl.obolibrary.org/obo/GO_1902458 GO:0001690 biolink:CellularComponent obsolete cytoplasmic dynein light chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytoplasmic dynein light chain http://purl.obolibrary.org/obo/GO_0001690 GO:1902459 biolink:BiologicalProcess positive regulation of stem cell population maintenance Any process that activates or increases the frequency, rate or extent of stem cell population maintenance. go-plus.json upregulation of maintenance of pluripotency|up-regulation of stem cell maintenance|up regulation of maintenance of pluripotency|positive regulation of maintenance of pluripotency|upregulation of stem cell maintenance|activation of maintenance of pluripotency|up-regulation of maintenance of pluripotency|up regulation of stem cell maintenance|activation of stem cell maintenance http://purl.obolibrary.org/obo/GO_1902459 GO:1902456 biolink:BiologicalProcess regulation of stomatal opening Any process that modulates the frequency, rate or extent of stomatal opening. go-plus.json http://purl.obolibrary.org/obo/GO_1902456 GO:0001691 biolink:MolecularActivity pseudophosphatase activity Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues. go-plus.json http://purl.obolibrary.org/obo/GO_0001691 GO:1902457 biolink:BiologicalProcess negative regulation of stomatal opening Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening. go-plus.json downregulation of stomatal opening|down regulation of stomatal opening|inhibition of stomatal opening|down-regulation of stomatal opening http://purl.obolibrary.org/obo/GO_1902457 GO:0001692 biolink:BiologicalProcess histamine metabolic process The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json histamine metabolism http://purl.obolibrary.org/obo/GO_0001692 GO:0060030 biolink:BiologicalProcess dorsal convergence The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement. go-plus.json http://purl.obolibrary.org/obo/GO_0060030 GO:1902454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902454 GO:1902455 biolink:BiologicalProcess negative regulation of stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance. go-plus.json down-regulation of stem cell maintenance|down regulation of maintenance of pluripotency|inhibition of stem cell maintenance|downregulation of maintenance of pluripotency|negative regulation of maintenance of pluripotency|down-regulation of maintenance of pluripotency|down regulation of stem cell maintenance|downregulation of stem cell maintenance|inhibition of maintenance of pluripotency http://purl.obolibrary.org/obo/GO_1902455 GO:0060031 biolink:BiologicalProcess mediolateral intercalation The interdigitation of cells along the mediolateral axis during gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0060031 GO:0060032 biolink:BiologicalProcess notochord regression The developmental process in which the stucture of the notochord is destroyed in an embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0060032 GO:1902452 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902452 GO:0060033 biolink:BiologicalProcess anatomical structure regression The developmental process in which an anatomical stucture is destroyed as a part of its normal progression. go-plus.json tissue death|histolysis http://purl.obolibrary.org/obo/GO_0060033 GO:1902453 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902453 GO:1902461 biolink:BiologicalProcess negative regulation of mesenchymal stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation. go-plus.json down regulation of MSC proliferation|downregulation of mesenchymal stem cell proliferation|downregulation of MSC proliferation|down-regulation of mesenchymal stem cell proliferation|down-regulation of MSC proliferation|negative regulation of MSC proliferation|inhibition of mesenchymal stem cell proliferation|inhibition of MSC proliferation|down regulation of mesenchymal stem cell proliferation http://purl.obolibrary.org/obo/GO_1902461 GO:0060034 biolink:BiologicalProcess notochord cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060034 GO:0060035 biolink:BiologicalProcess notochord cell development The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060035 GO:1902462 biolink:BiologicalProcess positive regulation of mesenchymal stem cell proliferation Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation. go-plus.json upregulation of MSC proliferation|up regulation of mesenchymal stem cell proliferation|activation of mesenchymal stem cell proliferation|up regulation of MSC proliferation|activation of MSC proliferation|positive regulation of MSC proliferation|up-regulation of mesenchymal stem cell proliferation|up-regulation of MSC proliferation|upregulation of mesenchymal stem cell proliferation http://purl.obolibrary.org/obo/GO_1902462 GO:0060036 biolink:BiologicalProcess notochord cell vacuolation The assembly and arrangement of a vacuole within a cell of the notochord. go-plus.json http://purl.obolibrary.org/obo/GO_0060036 GO:1902460 biolink:BiologicalProcess regulation of mesenchymal stem cell proliferation Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation. go-plus.json regulation of MSC proliferation http://purl.obolibrary.org/obo/GO_1902460 GO:0060037 biolink:BiologicalProcess pharyngeal system development The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. go-plus.json http://purl.obolibrary.org/obo/GO_0060037 GO:0060038 biolink:BiologicalProcess cardiac muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. go-plus.json cardiac myocyte proliferation|cardiomyocyte proliferation|heart muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060038 GO:0060039 biolink:BiologicalProcess pericardium development The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. go-plus.json http://purl.obolibrary.org/obo/GO_0060039 GO:0098648 biolink:CellularComponent collagen anchoring fibril A specialised collagen fibril that functions as an anchor, binding to other collagen structures. go-plus.json http://purl.obolibrary.org/obo/GO_0098648 GO:0098649 biolink:BiologicalProcess obsolete response to peptidyl-dipeptidase A inhibitor OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidyl-dipeptidase A inhibitor stimulus. go-plus.json response to ACE inhibitor|response to angiotensin-converting enzyme inhibitor http://purl.obolibrary.org/obo/GO_0098649 GO:0098646 biolink:CellularComponent collagen sheet A protein complex that consists of collagen triple helices associated to form a sheet-like network. go-plus.json collagen hexagonal network http://purl.obolibrary.org/obo/GO_0098646 GO:0098647 biolink:CellularComponent collagen beaded filament A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure. go-plus.json beads on a string http://purl.obolibrary.org/obo/GO_0098647 GO:0098644 biolink:CellularComponent complex of collagen trimers A complex of collagen trimers such as a fibril or collagen network. go-plus.json Supramolecular collagen assembly|Supramolecular aggregate of collagen http://purl.obolibrary.org/obo/GO_0098644 GO:0098645 biolink:CellularComponent collagen network A supramolecular complex that consists of collagen triple helices associated to form a network. go-plus.json http://purl.obolibrary.org/obo/GO_0098645 GO:0098653 biolink:BiologicalProcess centromere clustering The process by which centromeres/kinetochores become localized to clusters. go-plus.json kinetochore clustering http://purl.obolibrary.org/obo/GO_0098653 GO:0098654 biolink:CellularComponent CENP-A recruiting complex A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere. go-plus.json MIS18 complex http://purl.obolibrary.org/obo/GO_0098654 CHEBI:144784 biolink:ChemicalSubstance omega-hydroxy-ultra-long chain fatty acylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144784 chebi_ph7_3 GO:0098651 biolink:CellularComponent basement membrane collagen trimer Any collagen timer that is part of a basement membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098651 GO:0098652 biolink:CellularComponent collagen type VII anchoring fibril An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis. go-plus.json http://purl.obolibrary.org/obo/GO_0098652 CHEBI:144785 biolink:ChemicalSubstance omega-linoleoyloxy-O-ultra-long chain acylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144785 chebi_ph7_3 GO:0098650 biolink:MolecularActivity peptidyl-proline 4-dioxygenase binding Binding to a peptidyl-proline 4-dioxygenase. go-plus.json http://purl.obolibrary.org/obo/GO_0098650 GO:1902469 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902469 GO:1902467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902467 GO:1902468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902468 GO:1902465 biolink:BiologicalProcess negative regulation of histone H3-K27 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation. go-plus.json inhibition of histone H3-K27 trimethylation|down regulation of histone H3-K27 trimethylation|downregulation of histone H3-K27 trimethylation|down-regulation of histone H3-K27 trimethylation http://purl.obolibrary.org/obo/GO_1902465 GO:1902466 biolink:BiologicalProcess positive regulation of histone H3-K27 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation. go-plus.json up-regulation of histone H3-K27 trimethylation|upregulation of histone H3-K27 trimethylation|up regulation of histone H3-K27 trimethylation|activation of histone H3-K27 trimethylation http://purl.obolibrary.org/obo/GO_1902466 GO:0060020 biolink:BiologicalProcess Bergmann glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060020 GO:0060021 biolink:BiologicalProcess roof of mouth development The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. go-plus.json palatum development http://purl.obolibrary.org/obo/GO_0060021 GO:1902463 biolink:BiologicalProcess protein localization to cell leading edge A process in which a protein is transported to, or maintained in, a location within a cell leading edge. go-plus.json protein localisation to cell leading edge|protein localization in cell leading edge|protein localisation in cell leading edge http://purl.obolibrary.org/obo/GO_1902463 GO:1902464 biolink:BiologicalProcess regulation of histone H3-K27 trimethylation Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_1902464 GO:0060022 biolink:BiologicalProcess hard palate development The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes. go-plus.json palatum durum development http://purl.obolibrary.org/obo/GO_0060022 GO:0060023 biolink:BiologicalProcess soft palate development The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate. go-plus.json palatum molle development|velum palatum development http://purl.obolibrary.org/obo/GO_0060023 GO:1902472 biolink:BiologicalProcess regulation of mitotic cytokinesis, site selection Any process that modulates the frequency, rate or extent of mitotic cytokinesis, site selection. go-plus.json http://purl.obolibrary.org/obo/GO_1902472 GO:1902473 biolink:BiologicalProcess regulation of protein localization to synapse Any process that modulates the frequency, rate or extent of protein localization to synapse. go-plus.json regulation of protein localisation to synapse http://purl.obolibrary.org/obo/GO_1902473 GO:0060024 biolink:BiologicalProcess rhythmic synaptic transmission Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit. go-plus.json http://purl.obolibrary.org/obo/GO_0060024 GO:1902470 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902470 GO:0060025 biolink:BiologicalProcess regulation of synaptic activity Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060025 GO:0060026 biolink:BiologicalProcess convergent extension The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis. Wikipedia:Convergent_extension go-plus.json http://purl.obolibrary.org/obo/GO_0060026 GO:1902471 biolink:BiologicalProcess regulation of mitotic actomyosin contractile ring localization Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring localization. go-plus.json http://purl.obolibrary.org/obo/GO_1902471 GO:0060027 biolink:BiologicalProcess convergent extension involved in gastrulation The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0060027 GO:0060028 biolink:BiologicalProcess convergent extension involved in axis elongation The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0060028 GO:0060029 biolink:BiologicalProcess convergent extension involved in organogenesis The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ. go-plus.json http://purl.obolibrary.org/obo/GO_0060029 GO:0098659 biolink:BiologicalProcess inorganic cation import across plasma membrane The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json inorganic cation import into cell http://purl.obolibrary.org/obo/GO_0098659 GO:0098657 biolink:BiologicalProcess import into cell The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. go-plus.json uptake http://purl.obolibrary.org/obo/GO_0098657 GO:0098658 biolink:BiologicalProcess inorganic anion import across plasma membrane The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json inorganic anion import into cell http://purl.obolibrary.org/obo/GO_0098658 GO:0098655 biolink:BiologicalProcess cation transmembrane transport The process in which a cation is transported across a membrane. go-plus.json ATP hydrolysis coupled cation transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 GO:0098656 biolink:BiologicalProcess anion transmembrane transport The process in which an anion is transported across a membrane. go-plus.json ATP hydrolysis coupled anion transmembrane transport http://purl.obolibrary.org/obo/GO_0098656 GO:0098620 biolink:MolecularActivity seryl-selenocysteinyl-tRNA kinase activity Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP. Reactome:R-HSA-2408507 go-plus.json http://purl.obolibrary.org/obo/GO_0098620 GO:0001675 biolink:BiologicalProcess acrosome assembly The formation of the acrosome from the spermatid Golgi. go-plus.json acrosome formation http://purl.obolibrary.org/obo/GO_0001675 GO:0001676 biolink:BiologicalProcess long-chain fatty acid metabolic process The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json long-chain fatty acid metabolism http://purl.obolibrary.org/obo/GO_0001676 GO:0098621 biolink:MolecularActivity phosphoseryl-selenocysteinyl-tRNA selenium transferase activity Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid. EC:2.9.1.2|Reactome:R-HSA-2408555|RHEA:25041 go-plus.json http://purl.obolibrary.org/obo/GO_0098621 GO:0001677 biolink:BiologicalProcess formation of translation initiation ternary complex Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). go-plus.json translation initiation ternary complex assembly http://purl.obolibrary.org/obo/GO_0001677 GO:0001678 biolink:BiologicalProcess cellular glucose homeostasis A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment. go-plus.json cell glucose homeostasis http://purl.obolibrary.org/obo/GO_0001678 CHEBI:144774 biolink:ChemicalSubstance linoleoyl containing 1,2,3-triacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_144774 chebi_ph7_3 GO:0001671 biolink:MolecularActivity ATPase activator activity Binds to and increases the activity of an ATP hydrolysis activity. Reactome:R-HSA-5251955|Reactome:R-HSA-5251959 go-plus.json ATPase stimulator activity http://purl.obolibrary.org/obo/GO_0001671 CHEBI:144775 biolink:ChemicalSubstance delphinidin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_144775 chebi_ph7_3 CHEBI:144776 biolink:ChemicalSubstance delphinidin 3-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_144776 chebi_ph7_3 GO:0001672 biolink:BiologicalProcess regulation of chromatin assembly or disassembly Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly. go-plus.json regulation of chromatin assembly/disassembly http://purl.obolibrary.org/obo/GO_0001672 GO:0001673 biolink:CellularComponent male germ cell nucleus The nucleus of a male germ cell, a reproductive cell in males. go-plus.json male germ-cell nucleus http://purl.obolibrary.org/obo/GO_0001673 CHEBI:144777 biolink:ChemicalSubstance pelargonidin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_144777 chebi_ph7_3 CHEBI:144778 biolink:ChemicalSubstance pelargonidin 3-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_144778 chebi_ph7_3 GO:0001674 biolink:CellularComponent female germ cell nucleus The nucleus of the female germ cell, a reproductive cell in females. go-plus.json female germ-cell nucleus http://purl.obolibrary.org/obo/GO_0001674 GO:0060050 biolink:BiologicalProcess positive regulation of protein glycosylation Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. go-plus.json positive regulation of protein amino acid glycosylation http://purl.obolibrary.org/obo/GO_0060050 GO:1902478 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902478 GO:0060051 biolink:BiologicalProcess negative regulation of protein glycosylation Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. go-plus.json negative regulation of protein amino acid glycosylation http://purl.obolibrary.org/obo/GO_0060051 GO:0001670 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001670 GO:1902479 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902479 GO:0060052 biolink:BiologicalProcess neurofilament cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins. go-plus.json neurofilament cytoskeleton organisation|neurofilament cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0060052 GO:1902476 biolink:BiologicalProcess chloride transmembrane transport The process in which chloride is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902476 GO:1902477 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902477 GO:0060053 biolink:CellularComponent neurofilament cytoskeleton Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0060053 GO:1902474 biolink:BiologicalProcess positive regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to synapse. go-plus.json up-regulation of protein localization to synapse|up-regulation of protein localisation to synapse|upregulation of protein localization to synapse|upregulation of protein localisation to synapse|up regulation of protein localization to synapse|activation of protein localization to synapse|up regulation of protein localisation to synapse|activation of protein localisation to synapse|positive regulation of protein localisation to synapse http://purl.obolibrary.org/obo/GO_1902474 GO:0060054 biolink:BiologicalProcess positive regulation of epithelial cell proliferation involved in wound healing Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. go-plus.json http://purl.obolibrary.org/obo/GO_0060054 GO:0060055 biolink:BiologicalProcess angiogenesis involved in wound healing Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. go-plus.json http://purl.obolibrary.org/obo/GO_0060055 GO:1902475 biolink:BiologicalProcess L-alpha-amino acid transmembrane transport The directed movement of L-alpha-amino acid across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902475 GO:1902483 biolink:BiologicalProcess cytotoxic T cell pyroptotic process Any pyroptotic process in a cytotoxic T cell. go-plus.json cytotoxic T cell apoptosis|cytotoxic T lymphocyte apoptotic process|cytotoxic T-lymphocyte apoptosis|cytotoxic T-cell apoptotic process|cytotoxic T cell apoptotic process|cytotoxic T-cell apoptosis|cytotoxic T-lymphocyte apoptotic process|cytotoxic T lymphocyte apoptosis http://purl.obolibrary.org/obo/GO_1902483 GO:0060056 biolink:BiologicalProcess mammary gland involution The tissue remodeling that removes differentiated mammary epithelia during weaning. go-plus.json http://purl.obolibrary.org/obo/GO_0060056 GO:0060057 biolink:BiologicalProcess apoptotic process involved in mammary gland involution Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death. go-plus.json apoptosis involved in mammary gland involution http://purl.obolibrary.org/obo/GO_0060057 GO:1902484 biolink:BiologicalProcess Sertoli cell apoptotic process Any apoptotic process in a Sertoli cell. go-plus.json Sertoli cell apoptosis http://purl.obolibrary.org/obo/GO_1902484 GO:1902481 biolink:BiologicalProcess gamma-tubulin complex assembly The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex. go-plus.json gamma-tubulin complex formation http://purl.obolibrary.org/obo/GO_1902481 GO:0060058 biolink:BiologicalProcess positive regulation of apoptotic process involved in mammary gland involution Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution. go-plus.json positive regulation of apoptosis involved in mammary gland involution http://purl.obolibrary.org/obo/GO_0060058 GO:1902482 biolink:BiologicalProcess regulatory T cell apoptotic process Any apoptotic process in a regulatory T cell. go-plus.json regulatory T-lymphocyte apoptosis|regulatory T-cell apoptotic process|regulatory T-lymphocyte apoptotic process|regulatory T cell apoptosis|regulatory T lymphocyte apoptosis|regulatory T lymphocyte apoptotic process|regulatory T-cell apoptosis http://purl.obolibrary.org/obo/GO_1902482 GO:0060059 biolink:BiologicalProcess embryonic retina morphogenesis in camera-type eye The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage. go-plus.json http://purl.obolibrary.org/obo/GO_0060059 GO:1902480 biolink:BiologicalProcess protein localization to mitotic spindle A process in which a protein is transported to, or maintained in, a location within a mitotic spindle. go-plus.json protein localisation to mitotic spindle|protein localization in mitotic spindle|protein localisation in mitotic spindle http://purl.obolibrary.org/obo/GO_1902480 GO:0098628 biolink:BiologicalProcess peptidyl-N-phospho-arginine dephosphorylation The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine. go-plus.json http://purl.obolibrary.org/obo/GO_0098628 GO:0098629 biolink:BiologicalProcess trans-Golgi network membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098629 GO:0098626 biolink:MolecularActivity methylseleninic acid reductase activity Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O. Reactome:R-HSA-5263616 go-plus.json http://purl.obolibrary.org/obo/GO_0098626 GO:0098627 biolink:MolecularActivity protein arginine phosphatase activity Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate. EC:3.9.1.2|RHEA:43380 go-plus.json http://purl.obolibrary.org/obo/GO_0098627 GO:0098624 biolink:MolecularActivity 3'-phosphoadenylylselenate reductase activity Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+. Reactome:R-HSA-2408548 go-plus.json PAPSe reductase activity http://purl.obolibrary.org/obo/GO_0098624 GO:0001679 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001679 GO:0098625 biolink:MolecularActivity methylselenol reductase activity Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O. Reactome:R-HSA-5263614 go-plus.json http://purl.obolibrary.org/obo/GO_0098625 GO:0098622 biolink:MolecularActivity selenodiglutathione-disulfide reductase activity Catalysis of the reaction: H+ + selenodiglutathione + NADPH => gluthathioselenol + glutathione + NADP+. Reactome:R-HSA-2408542|RHEA:34927 go-plus.json http://purl.obolibrary.org/obo/GO_0098622 GO:0098623 biolink:MolecularActivity selenite reductase activity Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O. Reactome:R-HSA-2408558 go-plus.json http://purl.obolibrary.org/obo/GO_0098623 GO:0001686 biolink:CellularComponent obsolete axonemal dynein light chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json axonemal dynein light chain http://purl.obolibrary.org/obo/GO_0001686 GO:0098631 biolink:MolecularActivity cell adhesion mediator activity The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell. go-plus.json protein binding involved in cell adhesion|cell adhesion molecule http://purl.obolibrary.org/obo/GO_0098631 GO:0098632 biolink:MolecularActivity cell-cell adhesion mediator activity The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell. go-plus.json protein binding involved in cell-cell adhesion|cell-cell adhesion molecule http://purl.obolibrary.org/obo/GO_0098632 GO:0001687 biolink:CellularComponent obsolete cytoplasmic dynein heavy chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytoplasmic dynein heavy chain http://purl.obolibrary.org/obo/GO_0001687 GO:0001688 biolink:CellularComponent obsolete cytoplasmic dynein intermediate chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytoplasmic dynein intermediate chain http://purl.obolibrary.org/obo/GO_0001688 GO:0001689 biolink:CellularComponent obsolete cytoplasmic dynein intermediate light chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytoplasmic dynein intermediate light chain http://purl.obolibrary.org/obo/GO_0001689 GO:0098630 biolink:BiologicalProcess aggregation of unicellular organisms The clustering together of unicellular organisms in suspension form aggregates. go-plus.json aggregation of single cell organisms http://purl.obolibrary.org/obo/GO_0098630 GO:0001682 biolink:BiologicalProcess tRNA 5'-leader removal Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P. go-plus.json tRNA 5' leader removal http://purl.obolibrary.org/obo/GO_0001682 GO:0001683 biolink:CellularComponent obsolete axonemal dynein heavy chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json axonemal dynein heavy chain http://purl.obolibrary.org/obo/GO_0001683 GO:0001684 biolink:CellularComponent obsolete axonemal dynein intermediate chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json axonemal dynein intermediate chain http://purl.obolibrary.org/obo/GO_0001684 GO:0001685 biolink:CellularComponent obsolete axonemal dynein intermediate light chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json axonemal dynein intermediate light chain http://purl.obolibrary.org/obo/GO_0001685 GO:0001680 biolink:BiologicalProcess tRNA 3'-terminal CCA addition Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition. MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN|KEGG_REACTION:R09382 go-plus.json transfer ribonucleate adenylyltransferase activity|tRNA-nucleotidyltransferase activity|transfer-RNA nucleotidyltransferase activity|-C-C-A pyrophosphorylase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase activity|transfer ribonucleate cytidylyltransferase activity|tRNA CCA-diphosphorylase activity|tRNA cytidylyltransferase activity|CTP(ATP):tRNA nucleotidyltransferase activity|transfer ribonucleate nucleotidyltransferase activity|ATP(CTP):tRNA nucleotidyltransferase activity|CCA-adding enzyme, tRNA adenylyltransferase, tRNA cytidylyltransferase, tRNA CCA-pyrophosphorylase activity|CCA-adding enzyme activity|CTP:tRNA cytidylyltransferase activity|ribonucleic cytidylyltransferase activity|transfer ribonucleate adenyltransferase activity|transfer ribonucleic adenylyl (cytidylyl) transferase activity|CCA tRNA nucleotidyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase activity|transfer RNA adenylyltransferase activity|ATP(CTP)-tRNA nucleotidyltransferase activity|tRNA adenylyl(cytidylyl)transferase activity|transfer ribonucleic acid nucleotidyl transferase activity http://purl.obolibrary.org/obo/GO_0001680 GO:1902489 biolink:BiologicalProcess hepatoblast apoptotic process Any apoptotic process in a hepatoblast. go-plus.json hepatoblast apoptosis http://purl.obolibrary.org/obo/GO_1902489 GO:0001681 biolink:MolecularActivity sialate O-acetylesterase activity Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate. EC:3.1.1.53|MetaCyc:SIALATE-O-ACETYLESTERASE-RXN go-plus.json sialate 9(4)-O-acetylesterase activity|N-acyl-O-acetylneuraminate O-acetylhydrolase activity|N-acetylneuraminate acetyltransferase activity http://purl.obolibrary.org/obo/GO_0001681 GO:0060040 biolink:BiologicalProcess retinal bipolar neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina. go-plus.json http://purl.obolibrary.org/obo/GO_0060040 GO:1902487 biolink:BiologicalProcess protein localization to non-growing cell tip A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip. go-plus.json protein localisation to non-growing cell tip|protein localisation in non-growing cell tip|protein localization in non-growing cell tip http://purl.obolibrary.org/obo/GO_1902487 GO:0060041 biolink:BiologicalProcess retina development in camera-type eye The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. go-plus.json retinal development|retina development in camera-style eye http://purl.obolibrary.org/obo/GO_0060041 GO:0060042 biolink:BiologicalProcess retina morphogenesis in camera-type eye The process in which the anatomical structure of the retina is generated and organized. go-plus.json retinogenesis|retina morphogenesis in camera-style eye http://purl.obolibrary.org/obo/GO_0060042 GO:1902488 biolink:BiologicalProcess cholangiocyte apoptotic process Any apoptotic process in a cholangiocyte. go-plus.json epithelial cell of bile duct apoptosis|epithelial cell of bile duct apoptotic process|cholangiocyte apoptosis http://purl.obolibrary.org/obo/GO_1902488 GO:0060043 biolink:BiologicalProcess regulation of cardiac muscle cell proliferation Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. go-plus.json regulation of cardiomyocyte proliferation|regulation of heart muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 GO:1902485 biolink:MolecularActivity L-cysteine binding Binding to L-cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_1902485 GO:0060044 biolink:BiologicalProcess negative regulation of cardiac muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. go-plus.json negative regulation of heart muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060044 GO:1902486 biolink:BiologicalProcess protein localization to growing cell tip A process in which a protein is transported to, or maintained in, a location within a growing cell tip. go-plus.json protein localisation to growing cell tip|protein localisation in growing cell tip|protein localization in growing cell tip http://purl.obolibrary.org/obo/GO_1902486 GO:0060045 biolink:BiologicalProcess positive regulation of cardiac muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. go-plus.json positive regulation of heart muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060045 GO:1902494 biolink:CellularComponent catalytic complex A protein complex which is capable of catalytic activity. go-plus.json enzyme complex http://purl.obolibrary.org/obo/GO_1902494 goslim_metagenomics GO:1902495 biolink:CellularComponent transmembrane transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1902495 GO:0060046 biolink:BiologicalProcess regulation of acrosome reaction Any process that modulates the frequency, rate or extent of the acrosome reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0060046 GO:1902492 biolink:BiologicalProcess positive regulation of sperm capacitation Any process that activates or increases the frequency, rate or extent of sperm capacitation. go-plus.json up regulation of sperm activation|upregulation of sperm capacitation|upregulation of sperm activation|up-regulation of sperm capacitation|activation of sperm capacitation|up-regulation of sperm activation|activation of sperm activation|up regulation of sperm capacitation|positive regulation of sperm activation http://purl.obolibrary.org/obo/GO_1902492 GO:0060047 biolink:BiologicalProcess heart contraction The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. go-plus.json hemolymph circulation|heart beating|cardiac contraction http://purl.obolibrary.org/obo/GO_0060047 GO:0011000 biolink:BiologicalProcess replication fork arrest at mating type locus A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus. go-plus.json http://purl.obolibrary.org/obo/GO_0011000 GO:1902493 biolink:CellularComponent acetyltransferase complex A protein complex which is capable of acetyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902493 GO:0060048 biolink:BiologicalProcess cardiac muscle contraction Muscle contraction of cardiac muscle tissue. go-plus.json heart muscle contraction http://purl.obolibrary.org/obo/GO_0060048 GO:1902490 biolink:BiologicalProcess regulation of sperm capacitation Any process that modulates the frequency, rate or extent of sperm capacitation. go-plus.json regulation of sperm activation http://purl.obolibrary.org/obo/GO_1902490 GO:0060049 biolink:BiologicalProcess regulation of protein glycosylation Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. go-plus.json regulation of protein amino acid glycosylation http://purl.obolibrary.org/obo/GO_0060049 GO:1902491 biolink:BiologicalProcess negative regulation of sperm capacitation Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation. go-plus.json down regulation of sperm capacitation|downregulation of sperm activation|inhibition of sperm capacitation|down regulation of sperm activation|inhibition of sperm activation|down-regulation of sperm capacitation|negative regulation of sperm activation|down-regulation of sperm activation|downregulation of sperm capacitation http://purl.obolibrary.org/obo/GO_1902491 GO:0098639 biolink:MolecularActivity collagen binding involved in cell-matrix adhesion Any collagen binding that occurs as part of cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0098639 GO:0098637 biolink:CellularComponent protein complex involved in cell-matrix adhesion Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0098637 GO:0098638 biolink:MolecularActivity laminin binding involved in cell-matrix adhesion Any laminin protein binding that occurs as part of cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0098638 GO:0098635 biolink:CellularComponent protein complex involved in cell-cell adhesion Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0098635 GO:0098636 biolink:CellularComponent protein complex involved in cell adhesion Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. go-plus.json cell adhesion complex http://purl.obolibrary.org/obo/GO_0098636 GO:0098633 biolink:MolecularActivity collagen fibril binding Binding to a collagen fibril. go-plus.json http://purl.obolibrary.org/obo/GO_0098633 GO:0098634 biolink:MolecularActivity cell-matrix adhesion mediator activity The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix. go-plus.json protein binding involved in cell-matrix adhesion|cell-matrix adhesion molecule http://purl.obolibrary.org/obo/GO_0098634 OBA:VT1000784 biolink:OntologyClass circulatory system trait The quality when measured in circulatory system. go-plus.json http://purl.obolibrary.org/obo/OBA_VT1000784 OBA:VT1000781 biolink:OntologyClass nervous/sensory system trait The quality when measured in nervous system. go-plus.json http://purl.obolibrary.org/obo/OBA_VT1000781 CHEBI:86570 biolink:ChemicalSubstance (5alpha)-cholestan-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86570 chebi_ph7_3 OPL:0000151 biolink:OntologyClass promastigote stage A parasite lifecycle stage of Trypanosomatids. In this stage, the flagellum is found anterior of nucleus and flagellum not attached to the cell body. The kinetoplast is located in front of the nucleus, near the anterior end of the body. (Wikipedia: Trypanosomatid) go-plus.json http://purl.obolibrary.org/obo/OPL_0000151 PO:0000372 biolink:OntologyClass metaxylem A portion of primary xylem (PO:0005849) tissue that has as part one or more metaxylem tracheary elements (PO:0025576) embedded in parenchyma (PO:0005421) tissue and may contain xylem fiber cells (PO:0000274). go-plus.json portion of metaxylem tissue (exact)|後生木部 (Japanese, exact)|metaxilema (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000372 CHEBI:37606 biolink:ChemicalSubstance octadecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37606 CHEBI:37607 biolink:ChemicalSubstance trans-octadec-9-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37607 chebi_ph7_3 CHEBI:86564 biolink:ChemicalSubstance 4-guanidinobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86564 CHEBI:13611 biolink:ChemicalSubstance 4-hydroxy carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_13611 OPL:0000149 biolink:OntologyClass metacyclic trypomastigote stage A trypomastigote stage of Trypanosoma species which are nondividing forms resistant to mammalian complement that have the capacity to infect mammalian cells. go-plus.json http://purl.obolibrary.org/obo/OPL_0000149 CHEBI:13614 biolink:ChemicalSubstance 6,7-dihydropteridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_13614 chebi_ph7_3 CHEBI:37604 biolink:ChemicalSubstance cis-octadec-9-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37604 chebi_ph7_3 CHEBI:37605 biolink:ChemicalSubstance octadec-9-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37605 chebi_ph7_3 CHEBI:37602 biolink:ChemicalSubstance allenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_37602 chebi_ph7_3 CHEBI:13610 biolink:ChemicalSubstance 3beta-hydroxysterol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_13610 chebi_ph7_3 GO:0035092 biolink:BiologicalProcess sperm chromatin condensation The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0035092 GO:0035093 biolink:BiologicalProcess spermatogenesis, exchange of chromosomal proteins The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin. go-plus.json somatic histone exchange|somatic histone replacement http://purl.obolibrary.org/obo/GO_0035093 GO:0035094 biolink:BiologicalProcess response to nicotine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0035094 GO:0035095 biolink:BiologicalProcess behavioral response to nicotine Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus. go-plus.json behavioural response to nicotine http://purl.obolibrary.org/obo/GO_0035095 GO:0035096 biolink:BiologicalProcess larval midgut cell programmed cell death The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ. go-plus.json larval midgut cell death|programmed cell death of larval midgut cells http://purl.obolibrary.org/obo/GO_0035096 GO:0035097 biolink:CellularComponent histone methyltransferase complex A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0035097 goslim_pir GO:0035098 biolink:CellularComponent ESC/E(Z) complex A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. go-plus.json Extra Sex Combs/Enhancer of Zeste complex|PRC2 complex http://purl.obolibrary.org/obo/GO_0035098 GO:0035099 biolink:BiologicalProcess hemocyte migration The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo. go-plus.json hemocyte cell migration|arthropod blood cell migration http://purl.obolibrary.org/obo/GO_0035099 GO:0050602 biolink:MolecularActivity monoprenyl isoflavone epoxidase activity Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives. EC:1.14.99.34|MetaCyc:1.14.99.34-RXN go-plus.json monoprenyl isoflavone monooxygenase activity|7-O-methylluteone,NADPH:O2 oxidoreductase activity|7-O-methylluteone:O2 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050602 GO:0050603 biolink:MolecularActivity thiophene-2-carbonyl-CoA monooxygenase activity Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+). EC:1.14.99.35|RHEA:18929|MetaCyc:1.14.99.35-RXN|UM-BBD_reactionID:r1235|KEGG_REACTION:R05742 go-plus.json thiophene-2-carboxyl-CoA monooxygenase activity|thiophene-2-carboxyl-CoA dehydrogenase activity|thiophene-2-carboxyl-CoA hydroxylase activity|thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050603 GO:0050600 biolink:MolecularActivity myristoyl-CoA 11-(E) desaturase activity Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O. RHEA:46396|EC:1.14.19.24|MetaCyc:1.14.99.31-RXN go-plus.json n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]|n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating] http://purl.obolibrary.org/obo/GO_0050600 GO:0035090 biolink:BiologicalProcess maintenance of apical/basal cell polarity Retaining the established polarization of a cell along its apical/basal axis. go-plus.json http://purl.obolibrary.org/obo/GO_0035090 GO:0035091 biolink:MolecularActivity phosphatidylinositol binding Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. go-plus.json phosphoinositide binding http://purl.obolibrary.org/obo/GO_0035091 GO:0050601 biolink:MolecularActivity myristoyl-CoA 11-(Z) desaturase activity Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O. EC:1.14.19.5|MetaCyc:1.14.99.32-RXN|RHEA:25852 go-plus.json delta(11)-palmitoyl-CoA desaturase|delta(11) desaturase|delta(11)-fatty-acid desaturase|Z/E11-desaturase|fatty acid delta(11)-desaturase http://purl.obolibrary.org/obo/GO_0050601 GO:0050606 biolink:MolecularActivity 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH. KEGG_REACTION:R04279|RHEA:29587|MetaCyc:1.2.1.45-RXN|EC:1.1.1.312 go-plus.json 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity|alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity|4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity|2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050606 PO:0000349 biolink:OntologyClass epidermal initial cell An initial cell (PO:0004011) that is part of an epidermis (PO:0005679) and gives rise to specialized cell types of the epidermis. go-plus.json epidermal initial (exact)|célula inicial de la epidermis (Spanish, exact)|表皮始原細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000349 GO:0050607 biolink:MolecularActivity mycothiol-dependent formaldehyde dehydrogenase activity Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+. RHEA:28502|EC:1.1.1.306|MetaCyc:1.2.1.66-RXN go-plus.json NAD/factor-dependent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase (mycothiol-formylating) http://purl.obolibrary.org/obo/GO_0050607 GO:0050604 biolink:MolecularActivity taxadiene 5-alpha-hydroxylase activity Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol. EC:1.14.14.176|MetaCyc:1.14.99.37-RXN|KEGG_REACTION:R06306|RHEA:14049 go-plus.json taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)|taxadiene 5a-hydroxylase activity|taxadiene 5alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050604 GO:0050605 biolink:MolecularActivity superoxide reductase activity Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin. EC:1.15.1.2|MetaCyc:1.15.1.2-RXN|RHEA:21324 go-plus.json rubredoxin:superoxide oxidoreductase activity|desulfoferrodoxin activity|neelaredoxin activity http://purl.obolibrary.org/obo/GO_0050605 GO:0050608 biolink:MolecularActivity vanillin dehydrogenase activity Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate. KEGG_REACTION:R05699|MetaCyc:1.2.1.67-RXN|EC:1.2.1.67|RHEA:13309 go-plus.json vanillin:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050608 GO:0050609 biolink:MolecularActivity phosphonate dehydrogenase activity Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate. UM-BBD_reactionID:r1055|RHEA:13173|EC:1.20.1.1|KEGG_REACTION:R05746|MetaCyc:1.20.1.1-RXN go-plus.json NAD:phosphite oxidoreductase activity|phosphite dehydrogenase activity|phosphonate:NAD+ oxidoreductase activity|NAD-dependent phosphite dehydrogenas activity http://purl.obolibrary.org/obo/GO_0050609 GO:0035089 biolink:BiologicalProcess establishment of apical/basal cell polarity The specification and formation of the polarity of a cell along its apical/basal axis. go-plus.json http://purl.obolibrary.org/obo/GO_0035089 CHEBI:13643 biolink:ChemicalSubstance glycol go-plus.json http://purl.obolibrary.org/obo/CHEBI_13643 GO:0035081 biolink:BiologicalProcess induction of programmed cell death by hormones Any process induced by hormones that directly activates any of the steps required for programmed cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0035081 GO:0035082 biolink:BiologicalProcess axoneme assembly The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. go-plus.json ciliary axoneme assembly|cilium axoneme biogenesis|flagellar axoneme assembly|axoneme biogenesis|flagellum axoneme assembly|cilium axoneme assembly http://purl.obolibrary.org/obo/GO_0035082 GO:0035083 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035083 GO:0035084 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035084 GO:0035085 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035085 UBERON:8000009 biolink:AnatomicalEntity Purkinje fiber network A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles. go-plus.json Purkinje fibre network http://purl.obolibrary.org/obo/UBERON_8000009 GO:0035086 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035086 GO:0035087 biolink:BiologicalProcess siRNA loading onto RISC involved in RNA interference The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference. go-plus.json RNA interference, siRNA loading onto RISC http://purl.obolibrary.org/obo/GO_0035087 UBERON:8000006 biolink:AnatomicalEntity left side of back Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. go-plus.json http://purl.obolibrary.org/obo/UBERON_8000006 UBERON:8000007 biolink:AnatomicalEntity right side of back Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. go-plus.json http://purl.obolibrary.org/obo/UBERON_8000007 GO:0035088 biolink:BiologicalProcess establishment or maintenance of apical/basal cell polarity Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components. go-plus.json http://purl.obolibrary.org/obo/GO_0035088 PO:0000351 biolink:OntologyClass guard mother cell A shoot epidermal cell that divides to produce the guard cells. go-plus.json célula madre de la célula guardiana (Spanish, exact)|孔辺母細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000351 GO:0050610 biolink:MolecularActivity methylarsonate reductase activity Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid. MetaCyc:1.20.4.2-RXN|KEGG_REACTION:R05748|RHEA:15969|EC:1.20.4.2|UM-BBD_reactionID:r0837|Reactome:R-HSA-5696230 go-plus.json glutathione:methylarsonate oxidoreductase activity|MMA(V) reductase activity http://purl.obolibrary.org/obo/GO_0050610 PO:0000332 biolink:OntologyClass epidermal pavement cell A shoot epidermal cell that is relatively unspecialized at maturity. go-plus.json 表皮被蓋細胞 (Japanese, exact)|célula del pavimento epidermal (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000332 GO:0050613 biolink:MolecularActivity delta14-sterol reductase activity Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol. Reactome:R-HSA-194674|EC:1.3.1.70|RHEA:18561|Reactome:R-HSA-194698|MetaCyc:1.3.1.70-RXN go-plus.json C-14 sterol reductase activity|4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity|sterol C14-reductase activity|sterol C-14 reductase activity|D14-sterol reductase activity http://purl.obolibrary.org/obo/GO_0050613 GO:0050614 biolink:MolecularActivity delta24-sterol reductase activity Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol. Reactome:R-HSA-196417|Reactome:R-HSA-6807064|EC:1.3.1.72|RHEA:13685|MetaCyc:1.3.1.72-RXN go-plus.json lanosterol Delta(24)-reductase activity|sterol:NADP+ delta24-oxidoreductase activity|lanosterol delta24-reductase activity|D24-sterol reductase activity http://purl.obolibrary.org/obo/GO_0050614 GO:0050611 biolink:MolecularActivity arsenate reductase (azurin) activity Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate. UM-BBD_reactionID:r0634|RHEA:18701|EC:1.20.9.1|MetaCyc:1.20.98.1-RXN go-plus.json arsenite:azurin oxidoreductase activity|arsenite oxidase activity http://purl.obolibrary.org/obo/GO_0050611 GO:0050612 biolink:MolecularActivity arsenate reductase (donor) activity Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+). RHEA:18449|KEGG_REACTION:R05752|MetaCyc:1.20.99.1-RXN|EC:1.20.99.1 go-plus.json arsenate:(acceptor) oxidoreductase activity|arsenate:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050612 GO:0035080 biolink:BiologicalProcess heat shock-mediated polytene chromosome puffing The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0035080 GO:0050617 biolink:MolecularActivity 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. MetaCyc:1.3.7.2-RXN|RHEA:10168|EC:1.3.7.2 go-plus.json PebA http://purl.obolibrary.org/obo/GO_0050617 GO:0050618 biolink:MolecularActivity phycoerythrobilin:ferredoxin oxidoreductase activity Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin. MetaCyc:1.3.7.3-RXN|EC:1.3.7.3|RHEA:22092 go-plus.json PebB|(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050618 GO:0050615 biolink:MolecularActivity 1,2-dihydrovomilenine reductase activity Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH. KEGG_REACTION:R05879|EC:1.3.1.73|RHEA:12320|MetaCyc:1.3.1.73-RXN go-plus.json 17-O-acetylnorajmaline:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050615 GO:0050616 biolink:MolecularActivity secologanin synthase activity Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O. EC:1.14.19.62|MetaCyc:1.3.3.9-RXN|RHEA:20585 go-plus.json loganin:oxygen oxidoreductase (ring-cleaving) http://purl.obolibrary.org/obo/GO_0050616 CHEBI:13637 biolink:ChemicalSubstance flavanone 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_13637 GO:0050619 biolink:MolecularActivity phytochromobilin:ferredoxin oxidoreductase activity Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. MetaCyc:1.3.7.4-RXN|EC:1.3.7.4|RHEA:16377 go-plus.json (3Z)-phytochromobilin:ferredoxin oxidoreductase activity|PFB synthase activity|phytochromobilin synthase activity|HY2|P-Phi-B synthase activity|PPhiB synthase activity http://purl.obolibrary.org/obo/GO_0050619 GO:0035078 biolink:BiologicalProcess induction of programmed cell death by ecdysone Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0035078 GO:0035079 biolink:BiologicalProcess polytene chromosome puffing The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals. go-plus.json http://purl.obolibrary.org/obo/GO_0035079 GO:0035070 biolink:BiologicalProcess salivary gland histolysis The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly. go-plus.json salivary gland regression http://purl.obolibrary.org/obo/GO_0035070 GO:0035071 biolink:BiologicalProcess salivary gland cell autophagic cell death The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis. go-plus.json programmed cell death of salivary gland cells by autophagy|salivary gland cell death|salivary gland cell programmed cell death by autophagy|autophagic cell death of salivary gland cells http://purl.obolibrary.org/obo/GO_0035071 GO:0035072 biolink:BiologicalProcess ecdysone-mediated induction of salivary gland cell autophagic cell death Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis. go-plus.json ecdysone-mediated induction of programmed cell death of salivary gland cells by autophagy|ecdysone-mediated induction of salivary gland cell programmed cell death by autophagy|ecdysone-mediated induction of autophagic cell death of salivary gland cells http://purl.obolibrary.org/obo/GO_0035072 GO:0035073 biolink:BiologicalProcess pupariation The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis. go-plus.json puparium biosynthesis|puparium formation http://purl.obolibrary.org/obo/GO_0035073 GO:0035074 biolink:BiologicalProcess pupation The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period. Wikipedia:Pupa go-plus.json prepupal-pupal transition|head eversion http://purl.obolibrary.org/obo/GO_0035074 GO:0035075 biolink:BiologicalProcess response to ecdysone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0035075 GO:0035076 biolink:BiologicalProcess ecdysone receptor-mediated signaling pathway The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex. go-plus.json ecdysone receptor-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0035076 GO:0035077 biolink:BiologicalProcess ecdysone-mediated polytene chromosome puffing The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation. go-plus.json http://purl.obolibrary.org/obo/GO_0035077 GO:0050620 biolink:MolecularActivity phycocyanobilin:ferredoxin oxidoreductase activity Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. RHEA:15309|MetaCyc:1.3.7.5-RXN|EC:1.3.7.5 go-plus.json (3Z)-phycocyanobilin:ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050620 GO:0050621 biolink:MolecularActivity tryptophan alpha,beta-oxidase activity Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+). EC:1.3.3.10|KEGG_REACTION:R05317|RHEA:19901|MetaCyc:1.4.3.17-RXN go-plus.json tryptophan a,b-oxidase activity|L-tryptophan alpha,beta-dehydrogenase activity|L-tryptophan 2',3'-oxidase activity|L-tryptophan:oxygen alpha,beta-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050621 GO:0050624 biolink:MolecularActivity vomilenine reductase activity Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine. MetaCyc:1.5.1.32-RXN|RHEA:16409|EC:1.5.1.32|KEGG_REACTION:R05878 go-plus.json 1,2-dihydrovomilenine:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050624 GO:0050625 biolink:MolecularActivity 2-hydroxy-1,4-benzoquinone reductase activity Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+). UM-BBD_reactionID:r0667|MetaCyc:1.6.5.7-RXN|RHEA:12428|EC:1.6.5.7|KEGG_REACTION:R05399 go-plus.json NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity|2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity|1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity|hydroxybenzoquinone reductase activity|1,2,4-trihydroxybenzene:NAD oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050625 GO:0050622 biolink:MolecularActivity glycine dehydrogenase (cyanide-forming) activity Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2. EC:1.4.99.5|MetaCyc:1.4.99.5-RXN|RHEA:15821 go-plus.json HCN synthase activity|hydrogen cyanide synthase activity|glycine:acceptor oxidoreductase (hydrogen-cyanide-forming) http://purl.obolibrary.org/obo/GO_0050622 GO:0050623 biolink:MolecularActivity berberine reductase activity Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH. MetaCyc:1.5.1.31-RXN|RHEA:21268|EC:1.5.1.31|KEGG_REACTION:R07169 go-plus.json (R)-tetrahydroberberine:NADP+ oxidoreductase activity|(R)-canadine synthase activity http://purl.obolibrary.org/obo/GO_0050623 GO:0050628 biolink:MolecularActivity 2-oxopropyl-CoM reductase (carboxylating) activity Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH. UM-BBD_reactionID:r0854|MetaCyc:1.8.1.5-RXN|KEGG_REACTION:R05713|RHEA:16977|EC:1.8.1.5 go-plus.json NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity|2-KPCC activity|NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity|2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0050628 GO:0050629 biolink:MolecularActivity tetrachloroethene reductive dehalogenase activity Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor. EC:1.21.99.5|MetaCyc:1.97.1.8-RXN|RHEA:20353 go-plus.json tetrachloroethene reductase activity|acceptor:trichloroethene oxidoreductase (chlorinating) http://purl.obolibrary.org/obo/GO_0050629 GO:0050626 biolink:MolecularActivity trimethylamine-N-oxide reductase (cytochrome c) activity Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+. Wikipedia:Trimethylamine_N-oxide_reductase|MetaCyc:1.7.2.3-RXN|RHEA:24236|EC:1.7.2.3 go-plus.json trimethylamine:cytochrome c oxidoreductase activity|TOR activity|TMAO reductase activity http://purl.obolibrary.org/obo/GO_0050626 OPL:0000194 biolink:OntologyClass Phlebotominae midgut A midgut that is a part of or originated from a sand fly of genus Phlebotominae. go-plus.json http://purl.obolibrary.org/obo/OPL_0000194 GO:0050627 biolink:MolecularActivity mycothione reductase activity Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione. MetaCyc:1.8.1.15-RXN|EC:1.8.1.15 go-plus.json mycothiol-disulfide reductase activity|mycothiol:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050627 GO:0035067 biolink:BiologicalProcess negative regulation of histone acetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein. go-plus.json downregulation of histone acetylation|down-regulation of histone acetylation|inhibition of histone acetylation|down regulation of histone acetylation http://purl.obolibrary.org/obo/GO_0035067 GO:0035068 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035068 GO:0035069 biolink:BiologicalProcess larval midgut histolysis The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly. go-plus.json larval midgut regression http://purl.obolibrary.org/obo/GO_0035069 GO:0035060 biolink:CellularComponent brahma complex A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof. go-plus.json BRM complex http://purl.obolibrary.org/obo/GO_0035060 GO:0035061 biolink:CellularComponent interchromatin granule A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). NIF_Subcellular:sao1049471211 go-plus.json ICG http://purl.obolibrary.org/obo/GO_0035061 GO:0035062 biolink:CellularComponent omega speckle A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs). go-plus.json http://purl.obolibrary.org/obo/GO_0035062 GO:0035063 biolink:BiologicalProcess nuclear speck organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized. go-plus.json nuclear speckle assembly|nuclear speck organisation|nuclear speckle organization|nuclear speck organization and biogenesis http://purl.obolibrary.org/obo/GO_0035063 GO:0035064 biolink:MolecularActivity methylated histone binding Binding to a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0035064 GO:0035065 biolink:BiologicalProcess regulation of histone acetylation Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0035065 GO:0035066 biolink:BiologicalProcess positive regulation of histone acetylation Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein. go-plus.json up regulation of histone acetylation|activation of histone acetylation|stimulation of histone acetylation|up-regulation of histone acetylation|upregulation of histone acetylation http://purl.obolibrary.org/obo/GO_0035066 GO:0050631 biolink:MolecularActivity corydaline synthase activity Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+). RHEA:14773|MetaCyc:2.1.1.147-RXN|KEGG_REACTION:R07241|EC:2.1.1.147 go-plus.json S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity http://purl.obolibrary.org/obo/GO_0050631 GO:0050632 biolink:MolecularActivity propionyl-CoA C2-trimethyltridecanoyltransferase activity Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA. Reactome:R-HSA-193533|Reactome:R-HSA-390224|KEGG_REACTION:R05330|MetaCyc:2.3.1.154-RXN|Reactome:R-HSA-192341|EC:2.3.1.176|Reactome:R-HSA-2066781|RHEA:10408 go-plus.json sterol carrier protein|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity|propionyl-CoA C(2)-trimethyltridecanoyltransferase activity|peroxisome sterol carrier protein thiolase|sterol carrier protein X-related thiolase activity|peroxisomal 3-oxoacyl coenzyme A thiolase|SCPx|3-oxopristanoyl-CoA hydrolase activity|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity|3-oxopristanoyl-CoA thiolase activity|oxopristanoyl-CoA thiolase activity http://purl.obolibrary.org/obo/GO_0050632 GO:0050630 biolink:MolecularActivity (iso)eugenol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol. MetaCyc:2.1.1.146-RXN|EC:2.1.1.146|RHEA:17081 go-plus.json S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity|isoeugenol O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0050630 NCBITaxon:203490 biolink:OrganismalEntity Fusobacteriia go-plus.json Fusobacteria http://purl.obolibrary.org/obo/NCBITaxon_203490 GO:0050635 biolink:MolecularActivity acridone synthase activity Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O. RHEA:22224|MetaCyc:2.3.1.159-RXN|EC:2.3.1.159|KEGG_REACTION:R07250 go-plus.json malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing) http://purl.obolibrary.org/obo/GO_0050635 OPL:0000181 biolink:OntologyClass parasite lifecycle stage A life cycle stage of a parasite. go-plus.json http://purl.obolibrary.org/obo/OPL_0000181 GO:0050636 biolink:MolecularActivity vinorine synthase activity Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine. KEGG_REACTION:R05876|RHEA:24016|MetaCyc:2.3.1.160-RXN|EC:2.3.1.160 go-plus.json acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing) http://purl.obolibrary.org/obo/GO_0050636 GO:0050633 biolink:MolecularActivity acetyl-CoA C-myristoyltransferase activity Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA. MetaCyc:2.3.1.155-RXN|EC:2.3.1.155|RHEA:18161 go-plus.json 3-oxopalmitoyl-CoA-CoA acetyltransferase activity|myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity|3-oxopalmitoyl-CoA hydrolase activity|myristoyl-CoA C-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050633 GO:0050634 biolink:MolecularActivity phloroisovalerophenone synthase activity Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one. RHEA:23572|MetaCyc:2.3.1.156-RXN|EC:2.3.1.156 go-plus.json isovaleryl-CoA:malonyl-CoA acyltransferase activity|valerophenone synthase activity|3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity http://purl.obolibrary.org/obo/GO_0050634 GO:0050639 biolink:MolecularActivity 10-hydroxytaxane O-acetyltransferase activity Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C. RHEA:18837|MetaCyc:2.3.1.163-RXN|KEGG_REACTION:R07252|EC:2.3.1.163 go-plus.json acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity|acetyl-CoA:taxan-10beta-ol O-acetyltransferase|acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050639 GO:0050637 biolink:MolecularActivity lovastatin nonaketide synthase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+). RHEA:18565|MetaCyc:2.3.1.161-RXN|KEGG_REACTION:R07251|EC:2.3.1.161 go-plus.json acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing) http://purl.obolibrary.org/obo/GO_0050637 GO:0050638 biolink:MolecularActivity taxadien-5-alpha-ol O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate. KEGG_REACTION:R06307|RHEA:22028|MetaCyc:2.3.1.162-RXN|EC:2.3.1.162 go-plus.json taxadien-5a-ol O-acetyltransferase activity|acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity|acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity|acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity|taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity|taxadien-5alpha-ol O-acetyltransferase activity|taxadienol acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050638 NCBITaxon:203491 biolink:OrganismalEntity Fusobacteriales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_203491 NCBITaxon:203492 biolink:OrganismalEntity Fusobacteriaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_203492 GO:0035056 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035056 GO:0035057 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035057 GO:0035058 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035058 GO:0035059 biolink:CellularComponent RCAF complex A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4. go-plus.json replication-coupling assembly factor complex http://purl.obolibrary.org/obo/GO_0035059 NCBITaxon:203488 biolink:OrganismalEntity Dictyoglomaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_203488 GO:0035050 biolink:BiologicalProcess embryonic heart tube development The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. go-plus.json http://purl.obolibrary.org/obo/GO_0035050 GO:0035051 biolink:BiologicalProcess cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. go-plus.json cardiac cell differentiation|heart cell differentiation http://purl.obolibrary.org/obo/GO_0035051 GO:0035052 biolink:BiologicalProcess dorsal vessel aortic cell fate commitment The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0035052 GO:0035053 biolink:BiologicalProcess dorsal vessel heart proper cell fate commitment The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0035053 GO:0035054 biolink:BiologicalProcess embryonic heart tube anterior/posterior pattern specification The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta. go-plus.json http://purl.obolibrary.org/obo/GO_0035054 GO:0035055 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035055 GO:0050642 biolink:MolecularActivity 2-alpha-hydroxytaxane 2-O-benzoyltransferase activity Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA. EC:2.3.1.166|KEGG_REACTION:R06310|MetaCyc:2.3.1.166-RXN|RHEA:18741 go-plus.json 2a-hydroxytaxane 2-O-benzoyltransferase activity|2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity|benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity|benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity|2alpha-hydroxytaxane 2-O-benzoyltransferase activity|benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity http://purl.obolibrary.org/obo/GO_0050642 GO:0050643 biolink:MolecularActivity 10-deacetylbaccatin III 10-O-acetyltransferase activity Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA. RHEA:20137|KEGG_REACTION:R06311|MetaCyc:2.3.1.167-RXN|EC:2.3.1.167 go-plus.json acetyl-CoA:taxan-10beta-ol O-acetyltransferase http://purl.obolibrary.org/obo/GO_0050643 GO:0050640 biolink:MolecularActivity isopenicillin-N N-acyltransferase activity Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate. EC:2.3.1.164|RHEA:20720|MetaCyc:2.3.1.164-RXN go-plus.json isopenicillin N:acyl-CoA acyltransferase activity|acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity|isopenicillin-N acyltransferase activity|acyl-CoA:isopenicillin N N-acyltransferase activity|acyl-coenzyme A:isopenicillin N acyltransferase activity http://purl.obolibrary.org/obo/GO_0050640 GO:0050641 biolink:MolecularActivity 6-methylsalicylic acid synthase activity Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+). EC:2.3.1.165|MetaCyc:2.3.1.165-RXN|RHEA:12240|KEGG_REACTION:R07253 go-plus.json acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)|6-MSAS activity|MSAS activity http://purl.obolibrary.org/obo/GO_0050641 GO:0050646 biolink:MolecularActivity 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding Binding to 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds. go-plus.json 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding http://purl.obolibrary.org/obo/GO_0050646 GO:0050647 biolink:MolecularActivity 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding Binding to 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds. go-plus.json 5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding http://purl.obolibrary.org/obo/GO_0050647 GO:0050644 biolink:MolecularActivity cis-p-coumarate glucosyltransferase activity Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP. MetaCyc:2.4.1.209-RXN|RHEA:13129|EC:2.4.1.209|KEGG_REACTION:R05324 go-plus.json UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050644 GO:0050645 biolink:MolecularActivity limonoid glucosyltransferase activity Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP. EC:2.4.1.210|RHEA:11256|MetaCyc:2.4.1.210-RXN go-plus.json LGTase activity|limonoid UDP-glucosyltransferase activity|uridine diphosphoglucose-limonoid glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050645 GO:0050648 biolink:MolecularActivity 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds. go-plus.json 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding http://purl.obolibrary.org/obo/GO_0050648 NCBITaxon:203486 biolink:OrganismalEntity Dictyoglomia go-plus.json Dictyoglomi http://purl.obolibrary.org/obo/NCBITaxon_203486 GO:0050649 biolink:MolecularActivity testosterone 6-beta-hydroxylase activity Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O. go-plus.json testosterone 6b-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050649 NCBITaxon:203487 biolink:OrganismalEntity Dictyoglomales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_203487 GO:0035045 biolink:BiologicalProcess sperm plasma membrane disassembly The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg. go-plus.json sperm plasma membrane catabolism|sperm plasma membrane degradation|sperm plasma membrane breakdown http://purl.obolibrary.org/obo/GO_0035045 CHEBI:13601 biolink:ChemicalSubstance 3-oxo-5alpha-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_13601 chebi_ph7_3 GO:0035046 biolink:BiologicalProcess pronuclear migration The directed movement of the male and female pronuclei towards each other prior to their fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0035046 GO:0035047 biolink:BiologicalProcess centrosomal and pronuclear rotation The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0035047 GO:0035048 biolink:BiologicalProcess obsolete splicing factor protein import into nucleus OBSOLETE. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane. go-plus.json splicing factor protein transport from cytoplasm to nucleus|splicing factor protein-nucleus import http://purl.obolibrary.org/obo/GO_0035048 GO:0035049 biolink:MolecularActivity juvenile hormone acid methyltransferase activity Catalysis of the transfer of a methyl group to juvenile hormone acid. go-plus.json http://purl.obolibrary.org/obo/GO_0035049 GO:0035040 biolink:BiologicalProcess sperm nuclear envelope removal Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0035040 GO:0035041 biolink:BiologicalProcess sperm chromatin decondensation Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0035041 GO:0035042 biolink:BiologicalProcess fertilization, exchange of chromosomal proteins Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity. go-plus.json sperm-specific histone replacement|sperm-specific histone exchange http://purl.obolibrary.org/obo/GO_0035042 GO:0035043 biolink:BiologicalProcess male pronuclear envelope synthesis Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation. go-plus.json http://purl.obolibrary.org/obo/GO_0035043 GO:0035044 biolink:BiologicalProcess sperm aster formation Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei. go-plus.json http://purl.obolibrary.org/obo/GO_0035044 GO:0050653 biolink:BiologicalProcess chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate. go-plus.json chondroitin sulfate proteoglycan formation, polysaccharide chain formation|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate proteoglycan chain elongation|chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism|chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis|chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis http://purl.obolibrary.org/obo/GO_0050653 GO:0050654 biolink:BiologicalProcess chondroitin sulfate proteoglycan metabolic process The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. go-plus.json chondroitin sulphate proteoglycan metabolic process|chondroitin sulfate proteoglycan metabolism|chondroitin sulphate proteoglycan metabolism http://purl.obolibrary.org/obo/GO_0050654 GO:0050651 biolink:BiologicalProcess dermatan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. go-plus.json dermatan sulfate proteoglycan synthesis|dermatan sulfate proteoglycan formation|chondroitin sulfate B proteoglycan biosynthesis|chondroitin sulfate B proteoglycan biosynthetic process|dermatan sulphate proteoglycan biosynthesis|dermatan sulphate proteoglycan biosynthetic process|dermatan sulfate proteoglycan anabolism|dermatan sulfate proteoglycan biosynthesis http://purl.obolibrary.org/obo/GO_0050651 GO:1902409 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902409 GO:0050652 biolink:BiologicalProcess dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate. go-plus.json chondroitin sulfate B proteoglycan chain elongation|dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis|dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan formation, polysaccharide chain formation|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan chain elongation http://purl.obolibrary.org/obo/GO_0050652 GO:0050657 biolink:BiologicalProcess nucleic acid transport The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0050657 GO:1902407 biolink:BiologicalProcess assembly of actomyosin apparatus involved in mitotic cytokinesis Any assembly of mitotic cytokinetic actomyosin apparatus. go-plus.json cytokinesis, formation of actomyosin apparatus involved in mitotic cell cycle|actomyosin apparatus assembly involved in cytokinesis involved in mitotic cell cycle|formation of actomyosin apparatus involved in cytokinesis involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902407 GO:0050658 biolink:BiologicalProcess RNA transport The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0050658 GO:1902408 biolink:BiologicalProcess mitotic cytokinesis, site selection Any cytokinesis, site selection that is involved in mitotic cell cycle. go-plus.json site selection involved in cell cycle cytokinesis involved in mitotic cell cycle|site selection involved in cytokinesis involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902408 GO:0050655 biolink:BiologicalProcess dermatan sulfate proteoglycan metabolic process The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. go-plus.json dermatan sulphate proteoglycan metabolism|dermatan sulfate proteoglycan metabolism|chondroitin sulfate B proteoglycan metabolic process|chondroitin sulfate B proteoglycan metabolism|dermatan sulphate proteoglycan metabolic process http://purl.obolibrary.org/obo/GO_0050655 GO:1902405 biolink:BiologicalProcess mitotic actomyosin contractile ring localization Any actomyosin contractile ring localization that is involved in mitotic cell cycle. go-plus.json contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902405 GO:1902406 biolink:BiologicalProcess mitotic actomyosin contractile ring maintenance Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle. go-plus.json cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle|contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902406 GO:0050656 biolink:MolecularActivity 3'-phosphoadenosine 5'-phosphosulfate binding Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. go-plus.json adenosine 3'-phosphate 5'-phosphosulfate binding|phosphoadenosine phosphosulfate binding|3'-phosphoadenosine 5'-phosphosulphate binding|3'-phosphoadenylyl-sulfate binding|PAPS binding http://purl.obolibrary.org/obo/GO_0050656 GO:1902403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902403 GO:1902404 biolink:BiologicalProcess mitotic actomyosin contractile ring contraction Any actomyosin contractile ring contraction that is involved in mitotic cell cycle. go-plus.json contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|mitotic actomyosin contractile ring constriction|cytokinesis, actomyosin ring contraction involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902404 GO:1902401 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic DNA damage checkpoint OBSOLETE. Any detection of stimulus that is involved in mitotic DNA damage checkpoint. go-plus.json stimulus sensing involved in mitotic DNA damage checkpoint|stimulus detection involved in mitotic DNA damage checkpoint|perception of stimulus involved in mitotic DNA damage checkpoint http://purl.obolibrary.org/obo/GO_1902401 GO:0050659 biolink:MolecularActivity N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. EC:2.8.2.33|KEGG_REACTION:R07288|KEGG_REACTION:R02181|Reactome:R-HSA-2018659|MetaCyc:RXN-7954|MetaCyc:RXN-7953 go-plus.json GalNAc4S-6ST|3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity|N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0050659 GO:1902402 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902402 GO:1902400 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902400 OBA:VT1000777 biolink:OntologyClass urinary system trait The quality when measured in renal system. go-plus.json http://purl.obolibrary.org/obo/OBA_VT1000777 GO:0035034 biolink:MolecularActivity histone acetyltransferase regulator activity Binds to and modulates the activity of histone acetyltransferase. go-plus.json histone acetylase regulator activity http://purl.obolibrary.org/obo/GO_0035034 GO:0035035 biolink:MolecularActivity histone acetyltransferase binding Binding to an histone acetyltransferase. go-plus.json histone acetylase binding http://purl.obolibrary.org/obo/GO_0035035 GO:0035036 biolink:BiologicalProcess sperm-egg recognition The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization. go-plus.json http://purl.obolibrary.org/obo/GO_0035036 GO:0035037 biolink:BiologicalProcess sperm entry An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur. go-plus.json http://purl.obolibrary.org/obo/GO_0035037 GO:0035038 biolink:BiologicalProcess female pronucleus assembly Assembly of the haploid nucleus of the unfertilized egg. go-plus.json female pronucleus assembly http://purl.obolibrary.org/obo/GO_0035038 GO:0035039 biolink:BiologicalProcess male pronucleus assembly The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division. go-plus.json male pronucleus formation http://purl.obolibrary.org/obo/GO_0035039 GO:0035030 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035030 GO:0050650 biolink:BiologicalProcess chondroitin sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. go-plus.json chondroitin sulphate proteoglycan biosynthetic process|chondroitin sulfate proteoglycan anabolism|chondroitin sulfate proteoglycan biosynthesis|chondroitin sulphate proteoglycan biosynthesis|chondroitin sulfate proteoglycan synthesis|chondroitin sulfate proteoglycan formation http://purl.obolibrary.org/obo/GO_0050650 GO:0035031 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035031 GO:0035032 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class III A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI). go-plus.json class III PI3K complex|phosphoinositide 3-kinase complex, class III http://purl.obolibrary.org/obo/GO_0035032 GO:0035033 biolink:MolecularActivity histone deacetylase regulator activity Binds to and modulates the activity of histone deacetylase. go-plus.json http://purl.obolibrary.org/obo/GO_0035033 GO:0001810 biolink:BiologicalProcess regulation of type I hypersensitivity Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0001810 CHEBI:37556 biolink:ChemicalSubstance O-(alpha-D-mannosyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37556 CHEBI:62523 biolink:ChemicalSubstance (-)-trans-permethrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62523 chebi_ph7_3 CHEBI:37557 biolink:ChemicalSubstance O-(alpha-D-mannosyl)-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37557 CHEBI:62521 biolink:ChemicalSubstance trans-permethrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62521 CHEBI:37554 biolink:ChemicalSubstance fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_37554 CHEBI:37555 biolink:ChemicalSubstance omega-carboxyacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_37555 GO:0001819 biolink:BiologicalProcess positive regulation of cytokine production Any process that activates or increases the frequency, rate or extent of production of a cytokine. go-plus.json upregulation of cytokine production|positive regulation of cytokine secretion|up regulation of cytokine production|activation of cytokine production|stimulation of cytokine production|positive regulation of cytokine biosynthetic process|up-regulation of cytokine production http://purl.obolibrary.org/obo/GO_0001819 CHEBI:62527 biolink:ChemicalSubstance (3-phenoxyphenyl)methanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62527 chebi_ph7_3 CHEBI:62528 biolink:ChemicalSubstance (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62528 CHEBI:37558 biolink:ChemicalSubstance aryl dialkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37558 chebi_ph7_3 CHEBI:62526 biolink:ChemicalSubstance (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62526 chebi_ph7_3 GO:0001815 biolink:BiologicalProcess positive regulation of antibody-dependent cellular cytotoxicity Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity. go-plus.json upregulation of antibody-dependent cellular cytotoxicity|stimulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell death|up-regulation of antibody-dependent cellular cytotoxicity|activation of antibody-dependent cellular cytotoxicity|positive regulation of antibody-dependent cell killing|up regulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell killing|positive regulation of antibody-dependent cell death http://purl.obolibrary.org/obo/GO_0001815 GO:0001816 biolink:BiologicalProcess cytokine production The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json cytokine secretion|interferon secretion|interleukin production|interferon production|interleukin secretion|cytokine metabolic process|cytokine biosynthetic process http://purl.obolibrary.org/obo/GO_0001816 gocheck_do_not_annotate|goslim_pir GO:0001817 biolink:BiologicalProcess regulation of cytokine production Any process that modulates the frequency, rate, or extent of production of a cytokine. go-plus.json regulation of cytokine biosynthetic process|regulation of cytokine secretion|regulation of cytokine biosynthesis|regulation of cytokine anabolism|regulation of cytokine synthesis|regulation of cytokine formation http://purl.obolibrary.org/obo/GO_0001817 GO:0001818 biolink:BiologicalProcess negative regulation of cytokine production Any process that stops, prevents, or reduces the rate of production of a cytokine. go-plus.json down regulation of cytokine production|negative regulation of cytokine secretion|inhibition of cytokine biosynthetic process|downregulation of cytokine production|negative regulation of cytokine anabolism|negative regulation of cytokine synthesis|down-regulation of cytokine production|down regulation of cytokine biosynthetic process|negative regulation of cytokine formation|downregulation of cytokine biosynthetic process|inhibition of cytokine production|negative regulation of cytokine biosynthetic process|negative regulation of cytokine biosynthesis|down-regulation of cytokine biosynthetic process http://purl.obolibrary.org/obo/GO_0001818 GO:0001811 biolink:BiologicalProcess negative regulation of type I hypersensitivity Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response. go-plus.json down regulation of type I hypersensitivity|downregulation of type I hypersensitivity|down-regulation of type I hypersensitivity|inhibition of type I hypersensitivity http://purl.obolibrary.org/obo/GO_0001811 GO:0001812 biolink:BiologicalProcess positive regulation of type I hypersensitivity Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response. go-plus.json upregulation of type I hypersensitivity|up regulation of type I hypersensitivity|activation of type I hypersensitivity|stimulation of type I hypersensitivity|up-regulation of type I hypersensitivity http://purl.obolibrary.org/obo/GO_0001812 GO:0001813 biolink:BiologicalProcess regulation of antibody-dependent cellular cytotoxicity Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity. go-plus.json regulation of antibody dependent cell death|regulation of antibody-dependent cell killing|regulation of antibody dependent cell killing|regulation of antibody-dependent cell death http://purl.obolibrary.org/obo/GO_0001813 CHEBI:37550 biolink:ChemicalSubstance sphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37550 GO:0001814 biolink:BiologicalProcess negative regulation of antibody-dependent cellular cytotoxicity Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity. go-plus.json negative regulation of antibody-dependent cell death|negative regulation of antibody dependent cell death|negative regulation of antibody-dependent cell killing|down-regulation of antibody-dependent cellular cytotoxicity|downregulation of antibody-dependent cellular cytotoxicity|down regulation of antibody-dependent cellular cytotoxicity|negative regulation of antibody dependent cell killing|inhibition of antibody-dependent cellular cytotoxicity http://purl.obolibrary.org/obo/GO_0001814 GO:0001820 biolink:BiologicalProcess serotonin secretion The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. go-plus.json 5-hydroxytryptamine secretion|5-HT secretion|serotonin release http://purl.obolibrary.org/obo/GO_0001820 GO:0001821 biolink:BiologicalProcess histamine secretion The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. go-plus.json http://purl.obolibrary.org/obo/GO_0001821 CHEBI:62531 biolink:ChemicalSubstance (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62531 chebi_ph7_3 CHEBI:37568 biolink:ChemicalSubstance dTTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37568 chebi_ph7_3 CHEBI:37565 biolink:ChemicalSubstance GTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37565 chebi_ph7_3 CHEBI:62533 biolink:ChemicalSubstance oligogalacturonide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62533 CHEBI:37569 biolink:ChemicalSubstance (+)-abscisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37569 chebi_ph7_3 CHEBI:62537 biolink:ChemicalSubstance N-acylphosphatidylethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62537 chebi_ph7_3 GO:0001826 biolink:BiologicalProcess inner cell mass cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell. go-plus.json http://purl.obolibrary.org/obo/GO_0001826 GO:0001827 biolink:BiologicalProcess inner cell mass cell fate commitment The cell fate commitment of precursor cells that will become inner cell mass cells. go-plus.json http://purl.obolibrary.org/obo/GO_0001827 GO:0001828 biolink:BiologicalProcess inner cell mass cellular morphogenesis The morphogenesis of cells in the inner cell mass. go-plus.json http://purl.obolibrary.org/obo/GO_0001828 GO:0001829 biolink:BiologicalProcess trophectodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. go-plus.json trophectoderm cell differentiation http://purl.obolibrary.org/obo/GO_0001829 GO:0001822 biolink:BiologicalProcess kidney development The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. Wikipedia:Kidney_development go-plus.json nephrogenesis http://purl.obolibrary.org/obo/GO_0001822 CHEBI:37563 biolink:ChemicalSubstance CTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37563 chebi_ph7_3 GO:0001823 biolink:BiologicalProcess mesonephros development The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. go-plus.json Wolffian body development http://purl.obolibrary.org/obo/GO_0001823 GO:0001824 biolink:BiologicalProcess blastocyst development The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0001824 GO:0001825 biolink:BiologicalProcess blastocyst formation The initial formation of a blastocyst from a solid ball of cells known as a morula. go-plus.json http://purl.obolibrary.org/obo/GO_0001825 CHEBI:62545 biolink:ChemicalSubstance acyl alpha,alpha-trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62545 CHEBI:37534 biolink:ChemicalSubstance ribitol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37534 CHEBI:62546 biolink:ChemicalSubstance monoacyl alpha,alpha-trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62546 CHEBI:37532 biolink:ChemicalSubstance phorbol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_37532 CHEBI:62543 biolink:ChemicalSubstance 3-oxotetradecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62543 chebi_ph7_3 CHEBI:37533 biolink:ChemicalSubstance azo compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37533 CHEBI:62549 biolink:ChemicalSubstance acyl alpha,alpha-trehalose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_62549 CHEBI:62547 biolink:ChemicalSubstance polyacyl alpha,alpha-trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62547 CHEBI:62548 biolink:ChemicalSubstance 3-oxodecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62548 chebi_ph7_3 CHEBI:37537 biolink:ChemicalSubstance phorbol 13-acetate 12-myristate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37537 chebi_ph7_3 CHEBI:37530 biolink:ChemicalSubstance phosphatidylinositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37530 CHEBI:37531 biolink:ChemicalSubstance polyprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37531 CHEBI:62552 biolink:ChemicalSubstance polyacyl alpha,alpha-trehalose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_62552 CHEBI:86500 biolink:ChemicalSubstance N-myristoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86500 chebi_ph7_3 CHEBI:37545 biolink:ChemicalSubstance altrarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37545 CHEBI:37546 biolink:ChemicalSubstance D-altrarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37546 chebi_ph7_3 CHEBI:62554 biolink:ChemicalSubstance fumonisin B1(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62554 chebi_ph7_3 CHEBI:62555 biolink:ChemicalSubstance 3-hydroxyisovaleryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62555 chebi_ph7_3 GO:0001808 biolink:BiologicalProcess negative regulation of type IV hypersensitivity Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response. go-plus.json downregulation of type IV hypersensitivity|down regulation of type IV hypersensitivity|inhibition of type IV hypersensitivity|down-regulation of type IV hypersensitivity http://purl.obolibrary.org/obo/GO_0001808 CHEBI:37549 biolink:ChemicalSubstance glycoside phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37549 GO:0001809 biolink:BiologicalProcess positive regulation of type IV hypersensitivity Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response. go-plus.json upregulation of type IV hypersensitivity|stimulation of type IV hypersensitivity|activation of type IV hypersensitivity|up-regulation of type IV hypersensitivity|up regulation of type IV hypersensitivity http://purl.obolibrary.org/obo/GO_0001809 CHEBI:86506 biolink:ChemicalSubstance (9Z,12Z)-octadeca-9,12-dien-6-ynoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86506 CHEBI:62558 biolink:ChemicalSubstance (S)-3-hydroxylauroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62558 chebi_ph7_3 CHEBI:37547 biolink:ChemicalSubstance L-altrarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37547 chebi_ph7_3 CHEBI:86508 biolink:ChemicalSubstance alpha-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86508 GO:0001804 biolink:BiologicalProcess negative regulation of type III hypersensitivity Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response. go-plus.json down-regulation of type III hypersensitivity|inhibition of type III hypersensitivity|down regulation of type III hypersensitivity|downregulation of type III hypersensitivity http://purl.obolibrary.org/obo/GO_0001804 GO:0001805 biolink:BiologicalProcess positive regulation of type III hypersensitivity Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response. go-plus.json stimulation of type III hypersensitivity|up-regulation of type III hypersensitivity|upregulation of type III hypersensitivity|up regulation of type III hypersensitivity|activation of type III hypersensitivity http://purl.obolibrary.org/obo/GO_0001805 GO:0001806 biolink:BiologicalProcess type IV hypersensitivity An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation. Wikipedia:Type_IV_hypersensitivity go-plus.json delayed hypersensitivity response|delayed-type hypersensitivity http://purl.obolibrary.org/obo/GO_0001806 NCBITaxon:35128 biolink:OrganismalEntity Thalassiosira pseudonana go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_35128 GO:0001807 biolink:BiologicalProcess regulation of type IV hypersensitivity Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0001807 GO:0001800 biolink:BiologicalProcess negative regulation of type IIb hypersensitivity Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response. go-plus.json inhibition of type IIb hypersensitivity|down regulation of type IIb hypersensitivity|downregulation of type IIb hypersensitivity|down-regulation of type IIb hypersensitivity http://purl.obolibrary.org/obo/GO_0001800 GO:0001801 biolink:BiologicalProcess positive regulation of type IIb hypersensitivity Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response. go-plus.json up-regulation of type IIb hypersensitivity|upregulation of type IIb hypersensitivity|up regulation of type IIb hypersensitivity|activation of type IIb hypersensitivity|stimulation of type IIb hypersensitivity http://purl.obolibrary.org/obo/GO_0001801 NCBITaxon:35127 biolink:OrganismalEntity Thalassiosira go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_35127 GO:0001802 biolink:BiologicalProcess type III hypersensitivity An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue. Wikipedia:Type_III_hypersensitivity go-plus.json http://purl.obolibrary.org/obo/GO_0001802 GO:0001803 biolink:BiologicalProcess regulation of type III hypersensitivity Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0001803 NCBITaxon:1224 biolink:OrganismalEntity Proteobacteria go-plus.json Alphaproteobacteraeota|proteobacteria|purple photosynthetic bacteria|purple photosynthetic bacteria and relatives|Alphaproteobacteriota|purple bacteria|purple non-sulfur bacteria|purple bacteria and relatives http://purl.obolibrary.org/obo/NCBITaxon_1224 GO:1990950 biolink:BiologicalProcess metaphase/anaphase transition of meiosis II The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II. go-plus.json meiosis II metaphase/anaphase transition|second meiotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1990950 GO:1990951 biolink:BiologicalProcess obsolete manchette assembly OBSOLETE. The assembly and organization of the manchette, a tubular array of microtubules, possibly also containing actin filaments, that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. go-plus.json http://purl.obolibrary.org/obo/GO_1990951 CHEBI:37519 biolink:ChemicalSubstance cyclohepta-1,3,5-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37519 chebi_ph7_3 CHEBI:62563 biolink:ChemicalSubstance cellooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62563 CHEBI:37512 biolink:ChemicalSubstance organic thiophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37512 CHEBI:37511 biolink:ChemicalSubstance thiophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37511 CHEBI:62566 biolink:ChemicalSubstance CDP-1L-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62566 CHEBI:37515 biolink:ChemicalSubstance D-fructofuranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37515 GO:1990956 biolink:BiologicalProcess fibroblast chemotaxis The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_1990956 GO:1990957 biolink:CellularComponent NPHP complex A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways. go-plus.json NPHP module http://purl.obolibrary.org/obo/GO_1990957 GO:1990958 biolink:BiologicalProcess obsolete response to thyrotropin-releasing hormone OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. go-plus.json response to TRH http://purl.obolibrary.org/obo/GO_1990958 GO:1990959 biolink:BiologicalProcess eosinophil homeostasis The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json eosinocyte homeostasis|eosinophilic leucocyte homeostasis|eosinophilic leukocyte homeostasis|eosinophilic granulocyte homeostasis http://purl.obolibrary.org/obo/GO_1990959 GO:1990952 biolink:BiologicalProcess obsolete manchette disassembly OBSOLETE. A cellular process that results in the breakdown of a manchette. go-plus.json manchette clearance http://purl.obolibrary.org/obo/GO_1990952 GO:1990953 biolink:BiologicalProcess intramanchette transport The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments. go-plus.json IMT http://purl.obolibrary.org/obo/GO_1990953 GO:1990954 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990954 GO:1990955 biolink:MolecularActivity G-rich single-stranded DNA binding Binding to G-rich, single-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990955 GO:1990960 biolink:BiologicalProcess basophil homeostasis The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json basophilic leucocyte homeostasis http://purl.obolibrary.org/obo/GO_1990960 NCBITaxon:1236 biolink:OrganismalEntity Gammaproteobacteria go-plus.json Proteobacteria gamma subdivision|gamma subgroup|gamma subdivision|g-proteobacteria|Purple bacteria, gamma subdivision|gamma proteobacteria http://purl.obolibrary.org/obo/NCBITaxon_1236 PO:0000431 biolink:OntologyClass megasporocyte A sporocyte (PO:0006204) that produces four haploid (1n) megaspores (PO:0020019). go-plus.json Poaceae megasporocyte (narrow)|大胞子母細胞 (Japanese, exact)|MMC (exact)|Zea megasporocyte (narrow)|megasporocito (Spanish, exact)|megaspore mother cell (exact) http://purl.obolibrary.org/obo/PO_0000431 GO:1990961 biolink:BiologicalProcess xenobiotic detoxification by transmembrane export across the plasma membrane A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. go-plus.json drug transmembrane export http://purl.obolibrary.org/obo/GO_1990961 GO:1990962 biolink:BiologicalProcess xenobiotic transport across blood-brain barrier The directed movement of a xenobiotic through the blood-brain barrier. go-plus.json drug transport across blood-brain barrier http://purl.obolibrary.org/obo/GO_1990962 CHEBI:62571 biolink:ChemicalSubstance beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_62571 chebi_ph7_3 NCBITaxon:1239 biolink:OrganismalEntity Firmicutes go-plus.json low G+C Gram-positive bacteria|Bacillota|clostridial firmicutes|Bacillaeota|Low G+C firmicutes|Bacillus/Clostridium group|Firmacutes|Clostridium group firmicutes|firmicutes|low GC Gram+ http://purl.obolibrary.org/obo/NCBITaxon_1239 CHEBI:62574 biolink:ChemicalSubstance bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62574 CHEBI:86520 biolink:ChemicalSubstance (2R)-2-methyltetradecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86520 chebi_ph7_3 CHEBI:86521 biolink:ChemicalSubstance (2S)-2-methyltetradecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86521 chebi_ph7_3 CHEBI:62573 biolink:ChemicalSubstance CDP-1L-myo-inositol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62573 chebi_ph7_3 CHEBI:13534 biolink:ChemicalSubstance acyl-carrier protein go-plus.json http://purl.obolibrary.org/obo/CHEBI_13534 CHEBI:62576 biolink:ChemicalSubstance bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62576 chebi_ph7_3 CHEBI:37527 biolink:ChemicalSubstance acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37527 CHEBI:37528 biolink:ChemicalSubstance sn-glycerol 1-phosphates go-plus.json http://purl.obolibrary.org/obo/CHEBI_37528 CHEBI:37525 biolink:ChemicalSubstance O-phospho-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37525 CHEBI:37526 biolink:ChemicalSubstance tigliane go-plus.json http://purl.obolibrary.org/obo/CHEBI_37526 chebi_ph7_3 GO:1990967 biolink:BiologicalProcess obsolete multi-organism toxin transport OBSOLETE. The directed movement of a toxin into, out of or within a cell, or between cells where two or more organisms of the same or different species are involved. go-plus.json typhoid toxin transport http://purl.obolibrary.org/obo/GO_1990967 GO:1990968 biolink:BiologicalProcess modulation by host of RNA binding by virus A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA. go-plus.json modulation by host of viral protein:RNA interaction http://purl.obolibrary.org/obo/GO_1990968 GO:1990969 biolink:BiologicalProcess modulation by host of viral RNA-binding transcription factor activity A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor. go-plus.json modulation by host of viral Tat activity http://purl.obolibrary.org/obo/GO_1990969 GO:1990963 biolink:BiologicalProcess establishment of blood-retinal barrier Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type. go-plus.json establishment of BRB|establishment of blood-retina barrier http://purl.obolibrary.org/obo/GO_1990963 GO:1990964 biolink:CellularComponent actin cytoskeleton-regulatory complex A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat. go-plus.json http://purl.obolibrary.org/obo/GO_1990964 GO:1990965 biolink:MolecularActivity cytosylglucuronate decarboxylase activity Catalysis of the reaction: cytosylglucuronic acid + H(+) = cytosylarabinopyranose + CO(2). go-plus.json http://purl.obolibrary.org/obo/GO_1990965 GO:1990966 biolink:BiologicalProcess ATP generation from poly-ADP-D-ribose The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. go-plus.json http://purl.obolibrary.org/obo/GO_1990966 GO:1990970 biolink:MolecularActivity trans-activation response element binding Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter. go-plus.json TAR binding http://purl.obolibrary.org/obo/GO_1990970 GO:1990971 biolink:CellularComponent EMILIN complex Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures. go-plus.json Elastic microfibrillar interface 2 complex|Elastic microfibrillar interface 1 complex|EMILIN-2 complex|EMILIN-1 complex http://purl.obolibrary.org/obo/GO_1990971 GO:1990972 biolink:CellularComponent multimerin complex Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures. go-plus.json Multimerin-2 complex|Multimerin-1 complex|p155 complex|Elastic microfibrillar interface 4 complex|Elastic microfibrillar interface 3 complex|EMILIN-4 complex|EMILIN-3 complex|Platelet glycoprotein Ia* complex http://purl.obolibrary.org/obo/GO_1990972 GO:1990973 biolink:CellularComponent transmembrane actin-associated (TAN) line A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge). go-plus.json TAN line http://purl.obolibrary.org/obo/GO_1990973 GO:0050800 biolink:MolecularActivity obsolete hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement OBSOLETE. Catalysis of the hydrolysis of GTP to directly drive the cellular or subcellular transport of a substance. go-plus.json hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement http://purl.obolibrary.org/obo/GO_0050800 GO:0050801 biolink:BiologicalProcess ion homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell. go-plus.json electrolyte homeostasis|negative regulation of crystal formation|regulation of ion homeostasis http://purl.obolibrary.org/obo/GO_0050801 PO:0000423 biolink:OntologyClass plant zygote A native plant cell (PO:0025606) which is a whole plant (PO:0000003) in the plant zygote stage (PO:0001097). go-plus.json cigoto (Spanish, exact)|zygote (broad)|植物接合子、接合体 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000423 GO:0050804 biolink:BiologicalProcess modulation of chemical synaptic transmission Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. go-plus.json regulation of chemical synaptic transmission|modulation of synaptic transmission|regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 goslim_synapse GO:0050805 biolink:BiologicalProcess negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. go-plus.json down-regulation of synaptic transmission|inhibition of synaptic transmission|down regulation of synaptic transmission|downregulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0050805 GO:0050802 biolink:BiologicalProcess circadian sleep/wake cycle, sleep The part of the circadian sleep/wake cycle where the organism is asleep. go-plus.json http://purl.obolibrary.org/obo/GO_0050802 GO:0050803 biolink:BiologicalProcess regulation of synapse structure or activity Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). go-plus.json http://purl.obolibrary.org/obo/GO_0050803 GO:0050808 biolink:BiologicalProcess synapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). go-plus.json synapse morphogenesis|synapse organisation|synapse development|synapse organization and biogenesis http://purl.obolibrary.org/obo/GO_0050808 goslim_synapse|goslim_drosophila GO:0050809 biolink:MolecularActivity diazepam binding Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium. go-plus.json diazepam binding inhibitor activity|Valium binding http://purl.obolibrary.org/obo/GO_0050809 GO:0050806 biolink:BiologicalProcess positive regulation of synaptic transmission Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. go-plus.json up regulation of synaptic transmission|activation of synaptic transmission|stimulation of synaptic transmission|up-regulation of synaptic transmission|upregulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0050806 GO:0050807 biolink:BiologicalProcess regulation of synapse organization Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). go-plus.json regulation of synapse structure|regulation of synapse organization and biogenesis|regulation of synapse organisation http://purl.obolibrary.org/obo/GO_0050807 goslim_synapse GO:1990978 biolink:BiologicalProcess obsolete response to viscosity OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990978 GO:1990979 biolink:BiologicalProcess obsolete copper ion transport across blood-brain barrier OBSOLETE. The directed movement of copper ions passing through the blood-brain barrier. go-plus.json copper ion transport across BBB http://purl.obolibrary.org/obo/GO_1990979 GO:1990974 biolink:BiologicalProcess actin-dependent nuclear migration The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell. go-plus.json actin-dependent nuclear movement http://purl.obolibrary.org/obo/GO_1990974 GO:1990975 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990975 GO:1990976 biolink:BiologicalProcess protein transport along microtubule to mitotic spindle pole body The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990976 GO:1990977 biolink:BiologicalProcess obsolete negative regulation of mitotic DNA replication initiation from late origin OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_1990977 GO:1990981 biolink:BiologicalProcess obsolete regulation of protein localization to cell division site involved in cell separation after cytokinesis OBSOLETE. A regulation of protein localization to cell division site involved in cell separation after cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_1990981 GO:1990982 biolink:BiologicalProcess obsolete Immune memory response OBSOLETE. The immune response against a previously encountered antigen being quicker and quantitatively better compared with the primary response. go-plus.json http://purl.obolibrary.org/obo/GO_1990982 GO:1990983 biolink:BiologicalProcess tRNA demethylation The removal of a methyl group from one or more residues within a tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990983 GO:1990984 biolink:MolecularActivity tRNA demethylase activity Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990984 GO:0050811 biolink:MolecularActivity GABA receptor binding Binding to a gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor. go-plus.json gamma-aminobutyric acid receptor binding|4-aminobutanoate receptor binding|diazepam binding inhibitor activity|4-aminobutyrate receptor binding http://purl.obolibrary.org/obo/GO_0050811 GO:0050812 biolink:BiologicalProcess regulation of acyl-CoA biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA. go-plus.json regulation of acyl-CoA formation|regulation of acyl-CoA biosynthesis|regulation of acyl-CoA anabolism|regulation of acyl-CoA synthesis http://purl.obolibrary.org/obo/GO_0050812 GO:0050810 biolink:BiologicalProcess regulation of steroid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. go-plus.json regulation of steroid synthesis|regulation of steroid formation|regulation of steroid biosynthesis|regulation of steroidogenesis|regulation of steroid anabolism http://purl.obolibrary.org/obo/GO_0050810 GO:1990980 biolink:BiologicalProcess obsolete copper ion transport across blood-CSF barrier OBSOLETE. The directed movement of copper ions passing through the blood-cerebrospinal fluid barrier. go-plus.json copper ion transport across blood-cerebrospinal fluid barrier|copper ion transport across BCB http://purl.obolibrary.org/obo/GO_1990980 GO:0050815 biolink:MolecularActivity phosphoserine residue binding Binding to a phosphorylated serine residue within a protein. go-plus.json phosphoserine binding http://purl.obolibrary.org/obo/GO_0050815 GO:0050816 biolink:MolecularActivity phosphothreonine residue binding Binding to a phosphorylated threonine residue within a protein. go-plus.json phosphothreonine binding http://purl.obolibrary.org/obo/GO_0050816 GO:0050813 biolink:BiologicalProcess epothilone metabolic process The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer. go-plus.json epothilone metabolism http://purl.obolibrary.org/obo/GO_0050813 CHEBI:37507 biolink:ChemicalSubstance anthracenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37507 GO:0050814 biolink:BiologicalProcess epothilone biosynthetic process The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer. go-plus.json epothilone biosynthesis|epothilone synthesis|epothilone formation|epothilone anabolism http://purl.obolibrary.org/obo/GO_0050814 GO:0050819 biolink:BiologicalProcess negative regulation of coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. go-plus.json down regulation of coagulation|negative regulation of clotting|downregulation of coagulation|anticoagulant activity|down-regulation of coagulation|inhibition of coagulation http://purl.obolibrary.org/obo/GO_0050819 CHEBI:86542 biolink:ChemicalSubstance 2-hydroxyhexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86542 OPL:0000322 biolink:OntologyClass Trypanosomatida metacyclic stage A parasite lifecycle stage of trypanosomatidae in which the organism is infectious and does not multiply. go-plus.json http://purl.obolibrary.org/obo/OPL_0000322 CHEBI:86543 biolink:ChemicalSubstance 2-hydroxyoctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86543 GO:0050817 biolink:BiologicalProcess coagulation The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. go-plus.json clotting http://purl.obolibrary.org/obo/GO_0050817 goslim_pir GO:0050818 biolink:BiologicalProcess regulation of coagulation Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. go-plus.json regulation of clotting http://purl.obolibrary.org/obo/GO_0050818 OPL:0000323 biolink:OntologyClass Trypanosomatida procyclic stage A parasite lifecycle stage of trypanosomatidae in which the organism is in dividing form and it occurs in fly vector. go-plus.json http://purl.obolibrary.org/obo/OPL_0000323 GO:1990985 biolink:BiologicalProcess obsolete apoptosis in response to oxidative stress OBSOLETE. Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to oxidative stress. go-plus.json http://purl.obolibrary.org/obo/GO_1990985 GO:1990986 biolink:BiologicalProcess DNA recombinase disassembly The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases). go-plus.json Rad51 nucleoprotein filament disassembly http://purl.obolibrary.org/obo/GO_1990986 GO:0001895 biolink:BiologicalProcess retina homeostasis A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function. go-plus.json http://purl.obolibrary.org/obo/GO_0001895 GO:0001896 biolink:BiologicalProcess autolysis A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation. Wikipedia:Autolysis go-plus.json http://purl.obolibrary.org/obo/GO_0001896 GO:0001897 biolink:BiologicalProcess cytolysis by symbiont of host cells The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json cytolysis by organism of host cells|pathogenesis http://purl.obolibrary.org/obo/GO_0001897 GO:0001898 biolink:BiologicalProcess regulation of cytolysis by symbiont of host cells Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation by symbiont of cytolysis of host cells http://purl.obolibrary.org/obo/GO_0001898 GO:0001891 biolink:CellularComponent phagocytic cup An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome. go-plus.json http://purl.obolibrary.org/obo/GO_0001891 GO:0001892 biolink:BiologicalProcess embryonic placenta development The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. go-plus.json fetal placenta development http://purl.obolibrary.org/obo/GO_0001892 GO:0001893 biolink:BiologicalProcess maternal placenta development Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. go-plus.json decidua development http://purl.obolibrary.org/obo/GO_0001893 GO:0060190 biolink:BiologicalProcess negative regulation of protein desumoylation Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0060190 GO:0001894 biolink:BiologicalProcess tissue homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. go-plus.json tissue maintenance http://purl.obolibrary.org/obo/GO_0001894 GO:0060191 biolink:BiologicalProcess regulation of lipase activity Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0060191 GO:0060192 biolink:BiologicalProcess negative regulation of lipase activity Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0060192 GO:1902379 biolink:MolecularActivity chemoattractant activity involved in axon guidance Any chemoattractant activity that is involved in axon guidance. go-plus.json chemoattractant activity involved in axon pathfinding|chemoattractant activity involved in axon growth cone guidance|chemoattractant activity involved in axon chemotaxis http://purl.obolibrary.org/obo/GO_1902379 GO:0060193 biolink:BiologicalProcess positive regulation of lipase activity Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0060193 GO:0001890 biolink:BiologicalProcess placenta development The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. go-plus.json placentation|placental development http://purl.obolibrary.org/obo/GO_0001890 GO:0060194 biolink:BiologicalProcess regulation of antisense RNA transcription Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0060194 GO:0060195 biolink:BiologicalProcess negative regulation of antisense RNA transcription Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0060195 GO:1902377 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902377 GO:1902378 biolink:BiologicalProcess VEGF-activated neuropilin signaling pathway involved in axon guidance Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance. go-plus.json VEGF-Npn-1 signaling involved in axon pathfinding|VEGF-Npn-1 signaling involved in axon growth cone guidance|VEGF-Npn-1 signaling involved in axon guidance|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon growth cone guidance|VEGF-activated neuropilin signaling pathway involved in axon pathfinding|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon pathfinding|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon guidance|VEGF-activated neuropilin signaling pathway involved in axon chemotaxis|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon chemotaxis|VEGF-Npn-1 signaling involved in axon chemotaxis|VEGF-activated neuropilin signaling pathway involved in axon growth cone guidance http://purl.obolibrary.org/obo/GO_1902378 GO:0060196 biolink:BiologicalProcess positive regulation of antisense RNA transcription Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0060196 GO:1902375 biolink:BiologicalProcess nuclear tRNA 3'-trailer cleavage, endonucleolytic Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus. go-plus.json tRNA 3'-end cleavage, endonucleolytic in nucleus|tRNA 3'-end cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-end cleavage in nucleus|tRNA 3'-trailer cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-trailer cleavage in nucleus|endonucleolytic tRNA 3'-trailer cleavage in cell nucleus|endonucleolytic tRNA 3'-end cleavage in cell nucleus http://purl.obolibrary.org/obo/GO_1902375 GO:0060197 biolink:BiologicalProcess cloacal septation The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development. go-plus.json cloaca septation http://purl.obolibrary.org/obo/GO_0060197 GO:1902376 biolink:BiologicalProcess obsolete protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process OBSOLETE. Any protein denaturation that is involved in proteasomal ubiquitin-dependent protein catabolic process. go-plus.json protein denaturation involved in proteasomal ubiquitin-dependent protein degradation|protein denaturation involved in proteasomal pathway|protein denaturation involved in proteasomal ubiquitin-dependent protein breakdown|protein denaturation involved in proteasome pathway|protein denaturation involved in proteasomal processing|protein denaturation involved in proteasomal ubiquitin-dependent protein catabolism http://purl.obolibrary.org/obo/GO_1902376 GO:0060198 biolink:CellularComponent clathrin-sculpted vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release. go-plus.json clathrin sculpted vesicle http://purl.obolibrary.org/obo/GO_0060198 GO:1902384 biolink:BiologicalProcess glycyrrhetinate metabolic process The chemical reactions and pathways involving glycyrrhetinate. go-plus.json glycyrrhetinate metabolism http://purl.obolibrary.org/obo/GO_1902384 GO:0060199 biolink:CellularComponent clathrin-sculpted glutamate transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate. go-plus.json clathrin sculpted glutamate transport vesicle|clathrin sculpted glutamate constitutive secretory pathway transport vesicle http://purl.obolibrary.org/obo/GO_0060199 GO:1902385 biolink:BiologicalProcess glycyrrhetinate catabolic process The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate. go-plus.json glycyrrhetinate breakdown|glycyrrhetinate catabolism|glycyrrhetinate degradation http://purl.obolibrary.org/obo/GO_1902385 GO:1902382 biolink:BiologicalProcess 11-oxo-beta-amyrin catabolic process The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin. go-plus.json 11-oxo-beta-amyrin catabolism|11-oxo-beta-amyrin degradation|11-oxo-beta-amyrin breakdown http://purl.obolibrary.org/obo/GO_1902382 GO:1902383 biolink:BiologicalProcess 11-oxo-beta-amyrin biosynthetic process The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin. go-plus.json 11-oxo-beta-amyrin biosynthesis|11-oxo-beta-amyrin anabolism|11-oxo-beta-amyrin synthesis|11-oxo-beta-amyrin formation http://purl.obolibrary.org/obo/GO_1902383 GO:1990916 biolink:CellularComponent Isp3 layer of spore wall The outermost layers of the spore wall, as described in Schizosaccharomyces pombe. go-plus.json http://purl.obolibrary.org/obo/GO_1990916 GO:1902380 biolink:BiologicalProcess positive regulation of endoribonuclease activity Any process that activates or increases the frequency, rate or extent of endoribonuclease activity. go-plus.json up regulation of endoribonuclease activity|activation of endoribonuclease activity|up regulation of endonuclease G activity|positive regulation of endonuclease G activity|up-regulation of endoribonuclease activity|activation of endonuclease G activity|up-regulation of endonuclease G activity|upregulation of endoribonuclease activity|upregulation of endonuclease G activity http://purl.obolibrary.org/obo/GO_1902380 GO:1902381 biolink:BiologicalProcess 11-oxo-beta-amyrin metabolic process The chemical reactions and pathways involving 11-oxo-beta-amyrin. go-plus.json 11-oxo-beta-amyrin metabolism http://purl.obolibrary.org/obo/GO_1902381 GO:1990917 biolink:CellularComponent ooplasm The cytoplasm of an ovum. go-plus.json http://purl.obolibrary.org/obo/GO_1990917 GO:1990918 biolink:BiologicalProcess double-strand break repair involved in meiotic recombination The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination. go-plus.json http://purl.obolibrary.org/obo/GO_1990918 GO:1990919 biolink:MolecularActivity proteasome-nuclear membrane anchor activity The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome. go-plus.json nuclear membrane proteasome anchor|nuclear membrane proteasome adaptor|nuclear membrane proteasome tether|nuclear membrane proteasome tether activity|tethering factor for nuclear proteasome|nuclear membrane-proteasome tether activity|nuclear membrane-proteasome anchor activity http://purl.obolibrary.org/obo/GO_1990919 GO:1990912 biolink:BiologicalProcess obsolete response to microwave radiation OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microwave radiation stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990912 GO:1990913 biolink:CellularComponent sperm head plasma membrane The plasma membrane that is part of the head section of a sperm cell. go-plus.json http://purl.obolibrary.org/obo/GO_1990913 GO:1990914 biolink:CellularComponent integral component of periplasmic side of plasma membrane The component of the plasma membrane consisting of the gene products that penetrate only the periplasmic side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990914 GO:1990915 biolink:MolecularActivity structural constituent of ascospore wall The action of a molecule that contributes to the structural integrity of an ascospore wall. go-plus.json http://purl.obolibrary.org/obo/GO_1990915 GO:0001899 biolink:BiologicalProcess negative regulation of cytolysis by symbiont of host cells Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json down-regulation by symbiont of cytolysis of host cells|inhibition by symbiont of cytolysis of host cells|down regulation by symbiont of cytolysis of host cells|negative regulation by symbiont of cytolysis of host cells|downregulation by symbiont of cytolysis of host cells http://purl.obolibrary.org/obo/GO_0001899 GO:1990910 biolink:BiologicalProcess response to hypobaric hypoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level). go-plus.json http://purl.obolibrary.org/obo/GO_1990910 GO:1990911 biolink:BiologicalProcess response to psychosocial stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_1990911 NCBITaxon:1279 biolink:OrganismalEntity Staphylococcus go-plus.json Aurococcus http://purl.obolibrary.org/obo/NCBITaxon_1279 GO:0060180 biolink:BiologicalProcess female mating behavior The specific behavior of a female organism that is associated with reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0060180 GO:0060181 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060181 GO:0060182 biolink:MolecularActivity apelin receptor activity Combining with the peptide apelin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0060182 GO:0060183 biolink:BiologicalProcess apelin receptor signaling pathway The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands. go-plus.json apelin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060183 GO:0060184 biolink:BiologicalProcess cell cycle switching The process in which a cell switches cell cycle mode. go-plus.json http://purl.obolibrary.org/obo/GO_0060184 GO:1902388 biolink:MolecularActivity ceramide 1-phosphate transfer activity Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Reactome:R-HSA-5339535 go-plus.json intermembrane ceramide 1-phosphate transfer activity|ceramide 1-phosphate carrier activity|ceramide 1-phosphate transporter activity http://purl.obolibrary.org/obo/GO_1902388 GO:1902389 biolink:BiologicalProcess ceramide 1-phosphate transport The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1902389 GO:0060185 biolink:BiologicalProcess outer ear unfolding The opening and spreading out of the outer ear. go-plus.json http://purl.obolibrary.org/obo/GO_0060185 GO:0060186 biolink:BiologicalProcess outer ear emergence The growth of the outer ear. go-plus.json ear extroversion|outer ear growth|ear elevation http://purl.obolibrary.org/obo/GO_0060186 GO:1902386 biolink:BiologicalProcess glycyrrhetinate biosynthetic process The chemical reactions and pathways resulting in the formation of glycyrrhetinate. go-plus.json glycyrrhetinate anabolism|glycyrrhetinate synthesis|glycyrrhetinate formation|glycyrrhetinate biosynthesis http://purl.obolibrary.org/obo/GO_1902386 GO:0060187 biolink:CellularComponent cell pole Either of two different areas at opposite ends of an axis of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060187 GO:1902387 biolink:MolecularActivity ceramide 1-phosphate binding Binding to ceramide 1-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1902387 GO:1902395 biolink:BiologicalProcess regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity. go-plus.json regulation of 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity|regulation of 1-deoxyxylulose-5-phosphate synthase activity|regulation of DOXP synthase activity|regulation of pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)|regulation of DXP-synthase activity http://purl.obolibrary.org/obo/GO_1902395 GO:0060188 biolink:BiologicalProcess regulation of protein desumoylation Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0060188 GO:0060189 biolink:BiologicalProcess positive regulation of protein desumoylation Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0060189 GO:1902396 biolink:BiologicalProcess protein localization to bicellular tight junction A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. go-plus.json protein localisation in tight junction|protein localization in tight junction|protein localisation to tight junction http://purl.obolibrary.org/obo/GO_1902396 GO:1902393 biolink:BiologicalProcess negative regulation of exodeoxyribonuclease activity Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity. go-plus.json down regulation of exodeoxyribonuclease activity|downregulation of exodeoxyribonuclease activity|down-regulation of exodeoxyribonuclease activity|inhibition of exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_1902393 GO:1902394 biolink:BiologicalProcess positive regulation of exodeoxyribonuclease activity Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity. go-plus.json upregulation of exodeoxyribonuclease activity|up regulation of exodeoxyribonuclease activity|activation of exodeoxyribonuclease activity|up-regulation of exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_1902394 GO:1902391 biolink:BiologicalProcess positive regulation of N-terminal peptidyl-serine acetylation Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation. go-plus.json up regulation of N-terminal peptidyl-serine acetylation|upregulation of N-terminal peptidyl-serine acetylation|activation of N-terminal peptidyl-serine acetylation|up-regulation of N-terminal peptidyl-serine acetylation http://purl.obolibrary.org/obo/GO_1902391 GO:1990927 biolink:BiologicalProcess calcium ion regulated lysosome exocytosis The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. go-plus.json http://purl.obolibrary.org/obo/GO_1990927 GO:1990928 biolink:BiologicalProcess response to amino acid starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. go-plus.json http://purl.obolibrary.org/obo/GO_1990928 GO:1902392 biolink:BiologicalProcess regulation of exodeoxyribonuclease activity Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902392 GO:1990929 biolink:MolecularActivity sulfoquinovosidase activity Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose. go-plus.json http://purl.obolibrary.org/obo/GO_1990929 GO:1902390 biolink:BiologicalProcess regulation of N-terminal peptidyl-serine acetylation Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_1902390 GO:1990923 biolink:CellularComponent PET complex A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_1990923 GO:1990924 biolink:CellularComponent obsolete amphisome membrane OBSOLETE. The lipid bilayer surrounding the amphisome and separating its contents from the cell cytoplasm. go-plus.json amphisomal membrane http://purl.obolibrary.org/obo/GO_1990924 GO:1990925 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990925 GO:1990926 biolink:BiologicalProcess short-term synaptic potentiation The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds. go-plus.json synaptic facilitation http://purl.obolibrary.org/obo/GO_1990926 GO:1990920 biolink:BiologicalProcess proteasome localization to nuclear periphery Any process in which the proteasome is transported to, or maintained at the nuclear periphery. go-plus.json http://purl.obolibrary.org/obo/GO_1990920 NCBITaxon:1280 biolink:OrganismalEntity Staphylococcus aureus go-plus.json Staphylococcus pyogenes aureus|Staphylococcus aureus subsp. anaerobius|Micrococcus aureus|Staphlococcus pyogenes citreus|Micrococcus pyogenes http://purl.obolibrary.org/obo/NCBITaxon_1280 GO:1990921 biolink:BiologicalProcess obsolete proteasome localization to nuclear periphery OBSOLETE. A process in which a proteasome is transported to, or maintained in, a location within the nuclear periphery. go-plus.json proteasome localisation to nuclear periphery http://purl.obolibrary.org/obo/GO_1990921 GO:1990922 biolink:BiologicalProcess hepatic stellate cell proliferation The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver. go-plus.json Ito cell proliferation|hepatic perisinusoidal cell proliferation|perisinusoidal cell proliferation http://purl.obolibrary.org/obo/GO_1990922 GO:0001873 biolink:MolecularActivity polysaccharide immune receptor activity Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json polysaccharide receptor activity http://purl.obolibrary.org/obo/GO_0001873 GO:0098785 biolink:BiologicalProcess biofilm matrix assembly A process that results in the assembly of a biofilm matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0098785 GO:0098786 biolink:BiologicalProcess biofilm matrix disassembly A process that results in the disassembly of a biofilm matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0098786 GO:0001874 biolink:MolecularActivity (1->3)-beta-D-glucan immune receptor activity Combining with (1->3)-beta-D-glucans to initiate an innate immune response. go-plus.json (1->3)-beta-D-glucan receptor activity|beta-1,3-D-glucan receptor activity|(1,3)-beta-D-glucan receptor activity|1,3-beta-D-glucan receptor activity|zymosan receptor activity http://purl.obolibrary.org/obo/GO_0001874 GO:0098783 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098783 GO:0001875 biolink:MolecularActivity lipopolysaccharide immune receptor activity Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. go-plus.json endotoxin receptor activity|lipopolysaccharide receptor activity|LPS receptor activity http://purl.obolibrary.org/obo/GO_0001875 GO:0098784 biolink:BiologicalProcess biofilm matrix organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix. go-plus.json biofilm matrix organization and biogenesis http://purl.obolibrary.org/obo/GO_0098784 GO:0001876 biolink:MolecularActivity lipoarabinomannan binding Binding to lipoarabinomannan. go-plus.json LAM binding http://purl.obolibrary.org/obo/GO_0001876 GO:0098781 biolink:BiologicalProcess ncRNA transcription The transcription of non (protein) coding RNA from a DNA template. go-plus.json http://purl.obolibrary.org/obo/GO_0098781 GO:0098782 biolink:MolecularActivity mechanosensitived potassium channel activity Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress. go-plus.json mechanically-gated potassium channel activity http://purl.obolibrary.org/obo/GO_0098782 GO:0001870 biolink:BiologicalProcess positive regulation of complement activation, lectin pathway Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway. go-plus.json positive regulation of complement cascade, lectin pathway|upregulation of complement activation, lectin pathway|up regulation of complement activation, lectin pathway|activation of complement activation, lectin pathway|stimulation of complement activation, lectin pathway|up-regulation of complement activation, lectin pathway http://purl.obolibrary.org/obo/GO_0001870 GO:0001871 biolink:MolecularActivity obsolete pattern binding OBSOLETE. Binding to a repeating or polymeric structure, such as a polysaccharide or peptidoglycan. go-plus.json pattern recognition activity http://purl.obolibrary.org/obo/GO_0001871 GO:0001872 biolink:MolecularActivity (1->3)-beta-D-glucan binding Binding to a (1->3)-beta-D-glucan. go-plus.json 1,3-beta-D-glucan binding|zymosan binding|callose binding http://purl.obolibrary.org/obo/GO_0001872 GO:0098780 biolink:BiologicalProcess response to mitochondrial depolarisation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria. go-plus.json http://purl.obolibrary.org/obo/GO_0098780 GO:1902399 biolink:BiologicalProcess obsolete detection of stimulus involved in G1 DNA damage checkpoint OBSOLETE. Any detection of stimulus that is involved in G1 DNA damage checkpoint. go-plus.json perception of stimulus involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1 DNA damage checkpoint|perception of stimulus involved in G1 DNA damage checkpoint|stimulus detection involved in G1/S DNA damage checkpoint|stimulus detection involved in G1 DNA damage checkpoint|detection of stimulus involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1/S DNA damage checkpoint http://purl.obolibrary.org/obo/GO_1902399 GO:1902397 biolink:BiologicalProcess obsolete detection of stimulus involved in meiotic spindle checkpoint OBSOLETE. Any detection of stimulus that is involved in meiotic spindle checkpoint. go-plus.json perception of stimulus involved in meiotic spindle checkpoint|stimulus detection involved in meiotic spindle checkpoint|stimulus sensing involved in meiotic spindle checkpoint http://purl.obolibrary.org/obo/GO_1902397 GO:1902398 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902398 GO:1990938 biolink:BiologicalProcess peptidyl-aspartic acid autophosphorylation The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein. go-plus.json aspartyl autophosphorylation|peptidyl-aspartate autophosphorylation http://purl.obolibrary.org/obo/GO_1990938 GO:1990939 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990939 GO:1990934 biolink:CellularComponent nucleolus-like body A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles. go-plus.json NLB|compact nucleolus|nucleolus-like body http://purl.obolibrary.org/obo/GO_1990934 GO:1990935 biolink:MolecularActivity splicing factor binding Binding to a protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990935 GO:1990936 biolink:BiologicalProcess vascular associated smooth muscle cell dedifferentiation The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. go-plus.json vascular smooth muscle cell dedifferentiation http://purl.obolibrary.org/obo/GO_1990936 GO:1990937 biolink:BiologicalProcess xylan acetylation The addition of one or more acetyl groups to a xylan molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990937 GO:0001877 biolink:MolecularActivity lipoarabinomannan immune receptor activity Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response. go-plus.json LAM receptor activity|lipoarabinomannan receptor activity http://purl.obolibrary.org/obo/GO_0001877 GO:1990930 biolink:MolecularActivity mRNA N1-methyladenosine dioxygenase activity Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde. RHEA:49516|EC:1.14.11.54 go-plus.json RNA N1-methyladenosine dioxygenase activity|RNA N(1)-methyladenosine dioxygenase activity http://purl.obolibrary.org/obo/GO_1990930 GO:0098789 biolink:BiologicalProcess pre-mRNA cleavage required for polyadenylation The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation. go-plus.json cleavage and polyadenylylation specificity factor activity|pre-mRNA cleavage factor activity http://purl.obolibrary.org/obo/GO_0098789 GO:1990931 biolink:MolecularActivity mRNA N6-methyladenosine dioxygenase activity Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde. EC:1.14.11.53|RHEA:49520 go-plus.json mRNA N(6)-methyladenosine dioxygenase activity|RNA N6-methyladenosine dioxygenase activity|mRNA N(6)-methyladenine demethylase http://purl.obolibrary.org/obo/GO_1990931 GO:0001878 biolink:BiologicalProcess response to yeast Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species. go-plus.json http://purl.obolibrary.org/obo/GO_0001878 GO:1990932 biolink:MolecularActivity 5.8S rRNA binding Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990932 GO:0098787 biolink:BiologicalProcess mRNA cleavage involved in mRNA processing Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0098787 GO:0001879 biolink:BiologicalProcess detection of yeast The series of events in which a stimulus from a yeast is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0001879 GO:0098788 biolink:CellularComponent dendritic knob The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium. go-plus.json apical dendritic knob http://purl.obolibrary.org/obo/GO_0098788 GO:1990933 biolink:BiologicalProcess microtubule cytoskeleton attachment to nuclear envelope A process in which the microtubule cytoskeleton is attached to the nuclear envelope. go-plus.json http://purl.obolibrary.org/obo/GO_1990933 GO:0001884 biolink:MolecularActivity pyrimidine nucleoside binding Binding to a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0001884 GO:0098796 biolink:CellularComponent membrane protein complex Any protein complex that is part of a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098796 goslim_metagenomics GO:0098797 biolink:CellularComponent plasma membrane protein complex Any protein complex that is part of the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098797 GO:0001885 biolink:BiologicalProcess endothelial cell development The progression of an endothelial cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0001885 GO:0098794 biolink:CellularComponent postsynapse The part of a synapse that is part of the post-synaptic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098794 goslim_synapse GO:0001886 biolink:BiologicalProcess endothelial cell morphogenesis The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0001886 GO:1990940 biolink:BiologicalProcess obsolete microtubule sliding involved in mitotic spindle elongation OBSOLETE. The movement of one microtubule along another microtubule involved in mitotic spindle elongation. go-plus.json http://purl.obolibrary.org/obo/GO_1990940 GO:0098795 biolink:BiologicalProcess mRNA cleavage involved in gene silencing Cleavage of an mRNA occurring as part of the mechanism of gene silencing. go-plus.json http://purl.obolibrary.org/obo/GO_0098795 GO:0001887 biolink:BiologicalProcess selenium compound metabolic process The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine. go-plus.json selenium metabolic process|selenium compound metabolism|selenium metabolism http://purl.obolibrary.org/obo/GO_0001887 GO:0098792 biolink:BiologicalProcess xenophagy The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents. go-plus.json http://purl.obolibrary.org/obo/GO_0098792 GO:0001880 biolink:BiologicalProcess Mullerian duct regression The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos. go-plus.json http://purl.obolibrary.org/obo/GO_0001880 GO:0001881 biolink:BiologicalProcess receptor recycling The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal. go-plus.json http://purl.obolibrary.org/obo/GO_0001881 CHEBI:144842 biolink:ChemicalSubstance N(6)-methyl-AMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_144842 chebi_ph7_3 GO:0098793 biolink:CellularComponent presynapse The part of a synapse that is part of the presynaptic cell. go-plus.json presynaptic terminal http://purl.obolibrary.org/obo/GO_0098793 goslim_synapse GO:0098790 biolink:BiologicalProcess ncRNA transcription associated with protein coding gene TSS/TES The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes. go-plus.json pasRNA transcription http://purl.obolibrary.org/obo/GO_0098790 GO:0001882 biolink:MolecularActivity nucleoside binding Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0001882 goslim_pir GO:0001883 biolink:MolecularActivity purine nucleoside binding Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0001883 GO:0098791 biolink:CellularComponent Golgi apparatus subcompartment A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus. go-plus.json Golgi subcompartment http://purl.obolibrary.org/obo/GO_0098791 GO:1990949 biolink:BiologicalProcess metaphase/anaphase transition of meiosis I The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I. go-plus.json first meiotic metaphase/anaphase transition|meiosis I metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_1990949 GO:1990945 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990945 GO:1990946 biolink:BiologicalProcess meiosis I/meiosis II transition The cell cycle process in which a cell progresses from meiosis I to meiosis II. go-plus.json http://purl.obolibrary.org/obo/GO_1990946 GO:1990947 biolink:BiologicalProcess exit from meiosis Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half. go-plus.json meiotic exit http://purl.obolibrary.org/obo/GO_1990947 GO:1990948 biolink:MolecularActivity ubiquitin ligase inhibitor activity Binds to and stops, prevents or reduces the activity of a ubiquitin ligase. go-plus.json APC-Cdc20 complex inhibitor activity|mitotic anaphase-promoting complex inhibitor activity http://purl.obolibrary.org/obo/GO_1990948 GO:0001888 biolink:MolecularActivity glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan. RHEA:16221|EC:2.4.1.223|MetaCyc:2.4.1.223-RXN go-plus.json alpha1,4-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity|glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase I activity|alpha-1,4-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0001888 GO:1990941 biolink:CellularComponent mitotic spindle kinetochore microtubule Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation. go-plus.json http://purl.obolibrary.org/obo/GO_1990941 GO:1990942 biolink:BiologicalProcess mitotic metaphase chromosome recapture A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate. go-plus.json microtubule sliding involved in kinetochore retrieval|microtubule sliding involved in metaphase chromosome retrieval to the spindle pole body|sister kinetochore recapture|kinetochore retrieval|microtubule sliding involved in mitotic metaphase chromosome recapture|metaphase chromosome retrieval to the spindle pole body|microtubule sliding involved in sister kinetochore recapture http://purl.obolibrary.org/obo/GO_1990942 GO:0001889 biolink:BiologicalProcess liver development The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0001889 GO:1990943 biolink:MolecularActivity mating type region replication fork barrier binding Binding to the replication fork barrier found in the mating type region of fission yeast. go-plus.json RTS1 element binding|RTS1 barrier binding http://purl.obolibrary.org/obo/GO_1990943 GO:0098798 biolink:CellularComponent mitochondrial protein-containing complex A protein complex that is part of a mitochondrion. go-plus.json mitochondrial protein complex http://purl.obolibrary.org/obo/GO_0098798 gocheck_do_not_manually_annotate GO:0098799 biolink:CellularComponent outer mitochondrial membrane protein complex Any protein complex that is part of the outer mitochondrial membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098799 GO:1990944 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990944 GO:0001851 biolink:MolecularActivity complement component C3b binding Binding to a C3b product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001851 GO:0001852 biolink:MolecularActivity complement component iC3b binding Binding to a iC3b product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001852 GO:0001853 biolink:MolecularActivity complement component C3dg binding Binding to a C3dg product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001853 GO:0001854 biolink:MolecularActivity complement component C3d binding Binding to a C3d product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001854 GO:0001850 biolink:MolecularActivity complement component C3a binding Binding to a C3a product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001850 CHEBI:144833 biolink:ChemicalSubstance L-beta-ethynylserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_144833 CHEBI:37598 biolink:ChemicalSubstance nitrogen mustard go-plus.json http://purl.obolibrary.org/obo/CHEBI_37598 CHEBI:37592 biolink:ChemicalSubstance organic phosphonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37592 GO:0001859 biolink:MolecularActivity complement component C3dg receptor activity Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001859 GO:0001855 biolink:MolecularActivity complement component C4b binding Binding to a C4b product of the classical complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001855 GO:0001856 biolink:MolecularActivity complement component C5a binding Binding to a C5a product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001856 GO:0001857 biolink:MolecularActivity complement component C1q receptor activity Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001857 GO:0001858 biolink:MolecularActivity complement component iC3b receptor activity Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001858 GO:0001862 biolink:MolecularActivity collectin binding Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus. go-plus.json http://purl.obolibrary.org/obo/GO_0001862 GO:0001863 biolink:MolecularActivity collectin receptor activity Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001863 GO:0001864 biolink:MolecularActivity pentraxin binding Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array. go-plus.json http://purl.obolibrary.org/obo/GO_0001864 GO:0001865 biolink:BiologicalProcess NK T cell differentiation The process in which a precursor cell type acquires the specialized features of a NK T cell. go-plus.json natural T cell differentiation|NK T-cell differentiation|NT cell differentiation|NK T-lymphocyte differentiation|NK T cell development|NK T lymphocyte differentiation|natural killer T cell differentiation|NKT cell differentiation http://purl.obolibrary.org/obo/GO_0001865 GO:0001860 biolink:MolecularActivity complement component C3d receptor activity Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001860 GO:0001861 biolink:MolecularActivity complement component C4b receptor activity Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001861 GO:0001866 biolink:BiologicalProcess NK T cell proliferation The expansion of a NK T cell population by cell division. go-plus.json NK T-cell proliferation|NT cell proliferation|NK T-lymphocyte proliferation|NK T lymphocyte proliferation|natural killer T cell proliferation|NKT cell proliferation|natural T cell proliferation http://purl.obolibrary.org/obo/GO_0001866 GO:0001867 biolink:BiologicalProcess complement activation, lectin pathway Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. go-plus.json complement cascade, lectin pathway http://purl.obolibrary.org/obo/GO_0001867 GO:0001868 biolink:BiologicalProcess regulation of complement activation, lectin pathway Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation. go-plus.json regulation of complement cascade, lectin pathway http://purl.obolibrary.org/obo/GO_0001868 GO:0001869 biolink:BiologicalProcess negative regulation of complement activation, lectin pathway Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway. go-plus.json downregulation of complement activation, lectin pathway|down-regulation of complement activation, lectin pathway|inhibition of complement activation, lectin pathway|negative regulation of complement cascade, lectin pathway|down regulation of complement activation, lectin pathway http://purl.obolibrary.org/obo/GO_0001869 GO:0001830 biolink:BiologicalProcess trophectodermal cell fate commitment The cell fate commitment of precursor cells that will become trophectoderm cells. go-plus.json trophectoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0001830 GO:0001831 biolink:BiologicalProcess trophectodermal cellular morphogenesis The morphogenesis of trophectoderm cells. go-plus.json trophectoderm cellular morphogenesis http://purl.obolibrary.org/obo/GO_0001831 GO:0001832 biolink:BiologicalProcess blastocyst growth An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0001832 CHEBI:37578 biolink:ChemicalSubstance halide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37578 CHEBI:62501 biolink:ChemicalSubstance folate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62501 chebi_ph7_3 CHEBI:37579 biolink:ChemicalSubstance acyl halide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37579 CHEBI:37576 biolink:ChemicalSubstance gallate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_37576 CHEBI:37577 biolink:ChemicalSubstance heteroatomic molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_37577 CHEBI:62500 biolink:ChemicalSubstance methacrylyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62500 chebi_ph7_3 CHEBI:62505 biolink:ChemicalSubstance demethylspheroidene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62505 chebi_ph7_3 GO:0001837 biolink:BiologicalProcess epithelial to mesenchymal transition A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json epithelial-mesenchymal transition|mesenchymal cell differentiation from epithelial cell|EMT http://purl.obolibrary.org/obo/GO_0001837 CHEBI:62509 biolink:ChemicalSubstance 2-O-(alpha-D-glucopyranosyl)-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62509 GO:0001838 biolink:BiologicalProcess embryonic epithelial tube formation The morphogenesis of an embryonic epithelium into a tube-shaped structure. go-plus.json http://purl.obolibrary.org/obo/GO_0001838 GO:0001839 biolink:BiologicalProcess neural plate morphogenesis The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0001839 CHEBI:62508 biolink:ChemicalSubstance eudesmane sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62508 GO:0001833 biolink:BiologicalProcess inner cell mass cell proliferation The proliferation of cells in the inner cell mass. go-plus.json http://purl.obolibrary.org/obo/GO_0001833 CHEBI:37574 biolink:ChemicalSubstance thiamine(1+) monophosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37574 GO:0001834 biolink:BiologicalProcess trophectodermal cell proliferation The proliferation of cells in the trophectoderm. go-plus.json trophectoderm cell proliferation http://purl.obolibrary.org/obo/GO_0001834 CHEBI:144817 biolink:ChemicalSubstance 2-ammonio-2-deoxy-D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_144817 chebi_ph7_3 CHEBI:37575 biolink:ChemicalSubstance thiamine(1+) monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37575 chebi_ph7_3 GO:0001835 biolink:BiologicalProcess blastocyst hatching The hatching of the cellular blastocyst from the zona pellucida. go-plus.json http://purl.obolibrary.org/obo/GO_0001835 CHEBI:37573 biolink:ChemicalSubstance (2R)-DIMBOA glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_37573 chebi_ph7_3 GO:0001836 biolink:BiologicalProcess release of cytochrome c from mitochondria The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation. go-plus.json http://purl.obolibrary.org/obo/GO_0001836 GO:0001840 biolink:BiologicalProcess neural plate development The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0001840 GO:0001841 biolink:BiologicalProcess neural tube formation The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. Wikipedia:Neurulation go-plus.json neurulation|neural tube morphogenesis http://purl.obolibrary.org/obo/GO_0001841 GO:0001842 biolink:BiologicalProcess neural fold formation The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. go-plus.json neural groove formation http://purl.obolibrary.org/obo/GO_0001842 GO:0001843 biolink:BiologicalProcess neural tube closure The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. go-plus.json http://purl.obolibrary.org/obo/GO_0001843 NCBITaxon:1297 biolink:OrganismalEntity Deinococcus-Thermus go-plus.json Thermus/Deinococcus group|Deinococcota|Deinococcaeota http://purl.obolibrary.org/obo/NCBITaxon_1297 NCBITaxon:1298 biolink:OrganismalEntity Deinococcus go-plus.json Deinobacter http://purl.obolibrary.org/obo/NCBITaxon_1298 NCBITaxon:1299 biolink:OrganismalEntity Deinococcus radiodurans go-plus.json Deinococcus radiidurans|Micrococcus radiodurans http://purl.obolibrary.org/obo/NCBITaxon_1299 GO:1990909 biolink:CellularComponent Wnt signalosome A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein. go-plus.json LRP5/6 signalosome|Wnt signalosome complex|LRP6 signalosome|Wnt-LRP5/6 signalosome http://purl.obolibrary.org/obo/GO_1990909 CHEBI:62510 biolink:ChemicalSubstance 2-O-(alpha-D-glucopyranosyl)-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62510 chebi_ph7_3 CHEBI:37588 biolink:ChemicalSubstance phosphonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_37588 GO:1990905 biolink:CellularComponent dinoflagellate peduncle A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy). go-plus.json http://purl.obolibrary.org/obo/GO_1990905 GO:1990906 biolink:CellularComponent accessory outer segment A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors. go-plus.json http://purl.obolibrary.org/obo/GO_1990906 CHEBI:62517 biolink:ChemicalSubstance tricarballylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62517 chebi_ph7_3 GO:1990907 biolink:CellularComponent beta-catenin-TCF complex A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors. go-plus.json beta-catenin/LEF complex|beta-catenin/lymphoid enhancer binding factor complex|beta-catenin/T-cell factor complex http://purl.obolibrary.org/obo/GO_1990907 CHEBI:62514 biolink:ChemicalSubstance 10-epi-gamma-eudesmol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62514 chebi_ph7_3 GO:1990908 biolink:MolecularActivity obsolete Lys63-specific zinc metallopeptidase deubiquitinase activity OBSOLETE. Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein by a mechanism where zinc acts as the nucleophile. go-plus.json http://purl.obolibrary.org/obo/GO_1990908 GO:1990901 biolink:CellularComponent old cell pole The cell pole distal from the most recent cell division. go-plus.json http://purl.obolibrary.org/obo/GO_1990901 GO:0001848 biolink:MolecularActivity complement binding Binding to a component or product of the complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001848 CHEBI:37581 biolink:ChemicalSubstance gamma-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37581 chebi_ph7_3 GO:0001849 biolink:MolecularActivity complement component C1q complex binding Binding to a C1q complex, a component of the classical complement cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0001849 GO:1990902 biolink:CellularComponent new cell pole The cell pole proximal to the most recent cell division. go-plus.json http://purl.obolibrary.org/obo/GO_1990902 GO:1990903 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990903 GO:1990904 biolink:CellularComponent ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules. Wikipedia:Ribonucleoprotein go-plus.json ribonucleoprotein complex|extracellular ribonucleoprotein complex|RNP|RNA-protein complex|protein-RNA complex|intracellular ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_1990904 goslim_pir CHEBI:62519 biolink:ChemicalSubstance (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62519 GO:0001844 biolink:BiologicalProcess protein insertion into mitochondrial membrane involved in apoptotic signaling pathway The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway. go-plus.json insertion of proteins into mitochondrial membranes during the induction of apoptosis|protein insertion into mitochondrial membrane involved in induction of apoptosis|protein insertion into mitochondrion membrane during induction of apoptosis|protein insertion into mitochondrial membrane during induction of apoptosis http://purl.obolibrary.org/obo/GO_0001844 GO:0001845 biolink:BiologicalProcess phagolysosome assembly The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome. go-plus.json late phagosome biosynthesis|phagolysosome formation|late phagosome formation http://purl.obolibrary.org/obo/GO_0001845 CHEBI:37586 biolink:ChemicalSubstance sodium phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37586 GO:0001846 biolink:MolecularActivity opsonin binding Binding to an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material. go-plus.json http://purl.obolibrary.org/obo/GO_0001846 CHEBI:37584 biolink:ChemicalSubstance nicotinic acid dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37584 GO:1990900 biolink:CellularComponent ciliary pocket collar A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma. go-plus.json flagellum pocket collar|FPC|flagellar pocket collar|flagellar collar|flagellar pore|cilium pocket collar http://purl.obolibrary.org/obo/GO_1990900 GO:0001847 biolink:MolecularActivity opsonin receptor activity Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001847 GO:0050785 biolink:MolecularActivity advanced glycation end-product receptor activity Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins). go-plus.json RAGE activity|AGE receptor activity http://purl.obolibrary.org/obo/GO_0050785 GO:0098720 biolink:BiologicalProcess succinate import across plasma membrane The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json succinate import into cell http://purl.obolibrary.org/obo/GO_0098720 GO:0050786 biolink:MolecularActivity RAGE receptor binding Binding to a RAGE receptor, the receptor for advanced glycation end-products. go-plus.json advanced glycation end-product receptor binding http://purl.obolibrary.org/obo/GO_0050786 GO:0050783 biolink:BiologicalProcess cocaine metabolic process The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic. go-plus.json cocaine metabolism http://purl.obolibrary.org/obo/GO_0050783 GO:0050784 biolink:BiologicalProcess cocaine catabolic process The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic. go-plus.json cocaine degradation|cocaine catabolism|cocaine breakdown http://purl.obolibrary.org/obo/GO_0050784 GO:0050789 biolink:BiologicalProcess regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. go-plus.json regulation of physiological process http://purl.obolibrary.org/obo/GO_0050789 goslim_candida|gocheck_do_not_annotate|goslim_pir|goslim_aspergillus GO:0050787 biolink:BiologicalProcess detoxification of mercury ion Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]). go-plus.json http://purl.obolibrary.org/obo/GO_0050787 GO:0050788 biolink:BiologicalProcess sequestering of mercury The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system. go-plus.json mercury (Hg) ion sequestering|mercury (Hg) ion sequestration|retention of mercury (Hg2+) ion|sequestering of mercury (Hg) ion|sequestration of mercuric ion (Hg2+)|mercuric ion (Hg2+) sequestering|storage of mercury (Hg2+) ion|mercury (Hg2+) ion retention|mercury (Hg2+) ion storage|mercuric ion (Hg2+) sequestration|sequestration of mercury (Hg) ion|sequestering of mercuric ion (Hg2+) http://purl.obolibrary.org/obo/GO_0050788 GO:2001314 biolink:BiologicalProcess UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. go-plus.json UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose degradation|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose breakdown http://purl.obolibrary.org/obo/GO_2001314 GO:2001315 biolink:BiologicalProcess UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. go-plus.json UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose anabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose synthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose formation http://purl.obolibrary.org/obo/GO_2001315 GO:2001316 biolink:BiologicalProcess kojic acid metabolic process The chemical reactions and pathways involving kojic acid. go-plus.json C6H6O4 metabolic process|C6H6O4 metabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolism|kojic acid metabolism http://purl.obolibrary.org/obo/GO_2001316 GO:2001317 biolink:BiologicalProcess kojic acid biosynthetic process The chemical reactions and pathways resulting in the formation of kojic acid. go-plus.json 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|C6H6O4 biosynthetic process|C6H6O4 biosynthesis|C6H6O4 anabolism|C6H6O4 synthesis|kojic acid anabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|C6H6O4 formation|kojic acid synthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|kojic acid biosynthesis|kojic acid formation http://purl.obolibrary.org/obo/GO_2001317 GO:0060110 biolink:CellularComponent basal layer of collagen and cuticulin-based cuticle extracellular matrix The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans. go-plus.json basal layer of collagen and cuticulin-based exoskeleton extracellular matrix http://purl.obolibrary.org/obo/GO_0060110 GO:0035144 biolink:BiologicalProcess anal fin morphogenesis The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. go-plus.json http://purl.obolibrary.org/obo/GO_0035144 GO:0060111 biolink:CellularComponent alae of collagen and cuticulin-based cuticle extracellular matrix Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively. go-plus.json alae of collagen and cuticulin-based exoskeleton extracellular matrix http://purl.obolibrary.org/obo/GO_0060111 GO:0060112 biolink:BiologicalProcess generation of ovulation cycle rhythm The process which controls the timing of the type of sexual cycle seen in female mammals. go-plus.json generation of menstrual cycle rhythm|generation of estrus cycle rhythm|generation of oestrus cycle rhythm http://purl.obolibrary.org/obo/GO_0060112 GO:0035145 biolink:CellularComponent exon-exon junction complex A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. go-plus.json exon junction complex|EJC http://purl.obolibrary.org/obo/GO_0035145 GO:0060113 biolink:BiologicalProcess inner ear receptor cell differentiation The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. go-plus.json inner ear hair cell differentiation http://purl.obolibrary.org/obo/GO_0060113 GO:0035146 biolink:BiologicalProcess tube fusion The joining of specific branches of a tubular system to form a continuous network. go-plus.json http://purl.obolibrary.org/obo/GO_0035146 GO:0060114 biolink:BiologicalProcess vestibular receptor cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell. go-plus.json vestibular hair cell differentiation http://purl.obolibrary.org/obo/GO_0060114 GO:0035147 biolink:BiologicalProcess branch fusion, open tracheal system Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint. go-plus.json tracheal branch fusion http://purl.obolibrary.org/obo/GO_0035147 GO:2001310 biolink:BiologicalProcess gliotoxin biosynthetic process The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi. go-plus.json gliotoxin formation|gliotoxin biosynthesis|gliotoxin anabolism|gliotoxin synthesis http://purl.obolibrary.org/obo/GO_2001310 GO:0060115 biolink:BiologicalProcess vestibular receptor cell fate commitment The process in which a cell becomes committed to become a vestibular receptor cell. go-plus.json vestibular hair cell fate commitment http://purl.obolibrary.org/obo/GO_0060115 GO:0035148 biolink:BiologicalProcess tube formation Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. go-plus.json lumen formation in an anatomical structure|tube lumen formation http://purl.obolibrary.org/obo/GO_0035148 GO:0060116 biolink:BiologicalProcess vestibular receptor cell morphogenesis Any process that alters the size or shape of a vestibular receptor cell. go-plus.json vestibular hair cell morphogenesis http://purl.obolibrary.org/obo/GO_0060116 GO:2001311 biolink:BiologicalProcess lysobisphosphatidic acid metabolic process The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group. go-plus.json bis(monoacylglycerol) hydrogen phosphate metabolism|bis(monoacylglycerol) hydrogen phosphate metabolic process|LBPA metabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolic process|lysobisphosphatidic acid metabolism|LBPA metabolic process http://purl.obolibrary.org/obo/GO_2001311 GO:0035149 biolink:BiologicalProcess lumen formation, open tracheal system Creation of the central hole of a tube in an open tracheal system through which gases flow. go-plus.json tracheal lumen formation http://purl.obolibrary.org/obo/GO_0035149 GO:2001312 biolink:BiologicalProcess lysobisphosphatidic acid biosynthetic process The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group. go-plus.json bis(monoacylglycerol) hydrogen phosphate biosynthetic process|bis(monoacylglycerol) hydrogen phosphate biosynthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) anabolism|LBPA biosynthesis|LBPA biosynthetic process|bis(monoacylglycerol) hydrogen phosphate (BMP) synthesis|LBPA anabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) formation|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthetic process|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthesis|LBPA synthesis|bis(monoacylglycerol) hydrogen phosphate anabolism|LBPA formation|lysobisphosphatidic acid anabolism|bis(monoacylglycerol) hydrogen phosphate synthesis|bis(monoacylglycerol) hydrogen phosphate formation|lysobisphosphatidic acid synthesis|lysobisphosphatidic acid formation|lysobisphosphatidic acid biosynthesis http://purl.obolibrary.org/obo/GO_2001312 GO:0060117 biolink:BiologicalProcess auditory receptor cell development The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json auditory hair cell development http://purl.obolibrary.org/obo/GO_0060117 GO:0098729 biolink:BiologicalProcess germline stem cell symmetric division Division of a germline stem cell to produce two germline stem cells of the same type as the parent. go-plus.json http://purl.obolibrary.org/obo/GO_0098729 GO:2001313 biolink:BiologicalProcess UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. go-plus.json UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolism http://purl.obolibrary.org/obo/GO_2001313 GO:0060118 biolink:BiologicalProcess vestibular receptor cell development The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json vestibular hair cell development http://purl.obolibrary.org/obo/GO_0060118 GO:0098727 biolink:BiologicalProcess maintenance of cell number Any process by which the numbers of cells of a particular type or in a tissue are maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0098727 GO:0060119 biolink:BiologicalProcess inner ear receptor cell development The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json inner ear hair cell development http://purl.obolibrary.org/obo/GO_0060119 GO:0098728 biolink:BiologicalProcess germline stem cell asymmetric division The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes. go-plus.json http://purl.obolibrary.org/obo/GO_0098728 GO:0098725 biolink:BiologicalProcess symmetric cell division Cell division in which both daughter cells are of the same type. go-plus.json http://purl.obolibrary.org/obo/GO_0098725 GO:0098726 biolink:BiologicalProcess symmetric division of skeletal muscle satellite stem cell The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells. go-plus.json http://purl.obolibrary.org/obo/GO_0098726 GO:0098723 biolink:CellularComponent skeletal muscle myofibril A myofibril of a skeletal muscle fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0098723 GO:0050781 biolink:MolecularActivity ortho-trichlorophenol reductive dehalogenase activity Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl. go-plus.json 2,4,6-TCP reductive dehalogenase activity|2,4,6-trichlorophenol reductive dehalogenase activity http://purl.obolibrary.org/obo/GO_0050781 GO:0035140 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035140 GO:0035141 biolink:BiologicalProcess medial fin morphogenesis The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. go-plus.json median fin morphogenesis|unpaired fin morphogenesis http://purl.obolibrary.org/obo/GO_0035141 GO:0050782 biolink:MolecularActivity galactose uniporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in). go-plus.json galactose, glucose uniporter activity http://purl.obolibrary.org/obo/GO_0050782 GO:0098724 biolink:BiologicalProcess symmetric stem cell division Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population. go-plus.json http://purl.obolibrary.org/obo/GO_0098724 GO:0098721 biolink:BiologicalProcess uracil import across plasma membrane The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json uracil import into cell http://purl.obolibrary.org/obo/GO_0098721 GO:0035142 biolink:BiologicalProcess dorsal fin morphogenesis The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. go-plus.json http://purl.obolibrary.org/obo/GO_0035142 GO:0098722 biolink:BiologicalProcess asymmetric stem cell division Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. go-plus.json http://purl.obolibrary.org/obo/GO_0098722 GO:0035143 biolink:BiologicalProcess caudal fin morphogenesis The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035143 GO:0050780 biolink:MolecularActivity dopamine receptor binding Binding to a dopamine receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0050780 GO:0050796 biolink:BiologicalProcess regulation of insulin secretion Any process that modulates the frequency, rate or extent of the regulated release of insulin. go-plus.json http://purl.obolibrary.org/obo/GO_0050796 GO:0098730 biolink:BiologicalProcess male germline stem cell symmetric division The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic. go-plus.json http://purl.obolibrary.org/obo/GO_0098730 GO:0050797 biolink:MolecularActivity thymidylate synthase (FAD) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+. MetaCyc:RXN-8850|KEGG_REACTION:R06613|EC:2.1.1.148|RHEA:29043 go-plus.json flavin dependent thymidylate synthase activity|ThyX activity|FDTS activity|5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity|Thy1 activity http://purl.obolibrary.org/obo/GO_0050797 GO:0098731 biolink:BiologicalProcess skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. go-plus.json http://purl.obolibrary.org/obo/GO_0098731 GO:0050794 biolink:BiologicalProcess regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. go-plus.json regulation of cellular physiological process http://purl.obolibrary.org/obo/GO_0050794 GO:0050795 biolink:BiologicalProcess regulation of behavior Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. go-plus.json regulation of behaviour http://purl.obolibrary.org/obo/GO_0050795 GO:1902308 biolink:BiologicalProcess regulation of peptidyl-serine dephosphorylation Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation. go-plus.json http://purl.obolibrary.org/obo/GO_1902308 GO:1902309 biolink:BiologicalProcess negative regulation of peptidyl-serine dephosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation. go-plus.json down-regulation of peptidyl-serine dephosphorylation|inhibition of peptidyl-serine dephosphorylation|down regulation of peptidyl-serine dephosphorylation|downregulation of peptidyl-serine dephosphorylation http://purl.obolibrary.org/obo/GO_1902309 GO:1902306 biolink:BiologicalProcess negative regulation of sodium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport. go-plus.json inhibition of sodium ion transmembrane transport|down regulation of sodium ion membrane transport|downregulation of sodium ion membrane transport|down-regulation of sodium ion transmembrane transport|down-regulation of sodium ion membrane transport|negative regulation of sodium ion membrane transport|downregulation of sodium ion transmembrane transport|inhibition of sodium ion membrane transport|down regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1902306 GO:0050798 biolink:BiologicalProcess activated T cell proliferation The expansion of a T cell population following activation by an antigenic stimulus. go-plus.json proliferation of activated T cells|activated T-cell proliferation|activated T-lymphocyte proliferation|activated T lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0050798 GO:1902307 biolink:BiologicalProcess positive regulation of sodium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport. go-plus.json upregulation of sodium ion transmembrane transport|upregulation of sodium ion membrane transport|up-regulation of sodium ion transmembrane transport|activation of sodium ion transmembrane transport|up regulation of sodium ion membrane transport|positive regulation of sodium ion membrane transport|activation of sodium ion membrane transport|up regulation of sodium ion transmembrane transport|up-regulation of sodium ion membrane transport http://purl.obolibrary.org/obo/GO_1902307 GO:0050799 biolink:BiologicalProcess cocaine biosynthetic process The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic. go-plus.json cocaine biosynthesis|cocaine anabolism|cocaine synthesis|cocaine formation http://purl.obolibrary.org/obo/GO_0050799 GO:1902304 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902304 GO:1902305 biolink:BiologicalProcess regulation of sodium ion transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport. go-plus.json regulation of sodium ion membrane transport http://purl.obolibrary.org/obo/GO_1902305 GO:1902302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902302 GO:1902303 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902303 GO:1902300 biolink:BiologicalProcess galactarate transmembrane transport The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json D-galactarate transport|galactaric acid anion transport|galactarate transport http://purl.obolibrary.org/obo/GO_1902300 GO:1902301 biolink:MolecularActivity galactarate transmembrane transporter activity Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other. go-plus.json D-galactarate transmembrane transporter activity|galactaric acid anion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902301 GO:0060100 biolink:BiologicalProcess positive regulation of phagocytosis, engulfment Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0060100 GO:0035133 biolink:BiologicalProcess post-embryonic caudal fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035133 GO:0060101 biolink:BiologicalProcess negative regulation of phagocytosis, engulfment Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0060101 GO:0035134 biolink:BiologicalProcess post-embryonic dorsal fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. go-plus.json http://purl.obolibrary.org/obo/GO_0035134 GO:0060102 biolink:CellularComponent collagen and cuticulin-based cuticle extracellular matrix A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans. go-plus.json collagen and cuticulin-based exoskeleton extracellular matrix http://purl.obolibrary.org/obo/GO_0060102 GO:0035135 biolink:BiologicalProcess post-embryonic anal fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. go-plus.json http://purl.obolibrary.org/obo/GO_0035135 GO:0060103 biolink:CellularComponent obsolete collagen and cuticulin-based cuticle extracellular matrix part OBSOLETE. Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0060103 gocheck_do_not_annotate GO:0035136 biolink:BiologicalProcess forelimb morphogenesis The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. go-plus.json arm morphogenesis http://purl.obolibrary.org/obo/GO_0035136 GO:0060104 biolink:CellularComponent surface coat of collagen and cuticulin-based cuticle extracellular matrix An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans. go-plus.json surface coat of collagen and cuticulin-based exoskeleton extracellular matrix http://purl.obolibrary.org/obo/GO_0060104 GO:0035137 biolink:BiologicalProcess hindlimb morphogenesis The process in which the anatomical structures of the hindlimb are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0035137 GO:0060105 biolink:CellularComponent epicuticle of collagen and cuticulin-based cuticle extracellular matrix A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans. go-plus.json epicuticle of collagen and cuticulin-based exoskeleton extracellular matrix http://purl.obolibrary.org/obo/GO_0060105 GO:0035138 biolink:BiologicalProcess pectoral fin morphogenesis The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035138 GO:0035139 biolink:BiologicalProcess pelvic fin morphogenesis The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035139 GO:0060106 biolink:CellularComponent cortical layer of collagen and cuticulin-based cuticle extracellular matrix The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0060106 GO:0060107 biolink:CellularComponent annuli extracellular matrix The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present. go-plus.json annulae|annulus|annule(s)|annular rings http://purl.obolibrary.org/obo/GO_0060107 GO:0060108 biolink:CellularComponent annular furrow extracellular matrix The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline. go-plus.json http://purl.obolibrary.org/obo/GO_0060108 GO:0098738 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098738 GO:0060109 biolink:CellularComponent medial layer of collagen and cuticulin-based cuticle extracellular matrix The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals. go-plus.json medial layer struts http://purl.obolibrary.org/obo/GO_0060109 GO:0098739 biolink:BiologicalProcess import across plasma membrane The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json uptake http://purl.obolibrary.org/obo/GO_0098739 GO:0098736 biolink:BiologicalProcess negative regulation of the force of heart contraction Any process that decreases the force of heart muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0098736 GO:0098737 biolink:BiologicalProcess protein insertion into plasma membrane The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers. go-plus.json http://purl.obolibrary.org/obo/GO_0098737 GO:0050792 biolink:BiologicalProcess regulation of viral process Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts. go-plus.json regulation of viral process|regulation of viral reproduction http://purl.obolibrary.org/obo/GO_0050792 GO:0098734 biolink:BiologicalProcess macromolecule depalmitoylation The removal of palymitoyl groups from a macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0098734 GO:0035130 biolink:BiologicalProcess post-embryonic pectoral fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035130 GO:0050793 biolink:BiologicalProcess regulation of developmental process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). go-plus.json http://purl.obolibrary.org/obo/GO_0050793 GO:0098735 biolink:BiologicalProcess positive regulation of the force of heart contraction Any process that increases the force of heart muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0098735 GO:0050790 biolink:BiologicalProcess regulation of catalytic activity Any process that modulates the activity of an enzyme. go-plus.json regulation of enzyme activity|regulation of metalloenzyme activity http://purl.obolibrary.org/obo/GO_0050790 goslim_chembl GO:0035131 biolink:BiologicalProcess post-embryonic pelvic fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035131 GO:0098732 biolink:BiologicalProcess macromolecule deacylation The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0098732 GO:0098733 biolink:CellularComponent hemidesmosome associated protein complex Any protein complex that is part of or has some part in a hemidesmosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098733 GO:0035132 biolink:BiologicalProcess post-embryonic medial fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. go-plus.json post-embryonic unpaired fin morphogenesis http://purl.obolibrary.org/obo/GO_0035132 GO:0050791 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050791 GO:1902319 biolink:BiologicalProcess DNA strand elongation involved in nuclear cell cycle DNA replication Any DNA strand elongation that is involved in nuclear cell cycle DNA replication. go-plus.json DNA strand elongation involved in DNA replication involved in S phase|DNA strand elongation involved in DNA replication involved in S-phase|DNA strand elongation involved in DNA replication during S phase http://purl.obolibrary.org/obo/GO_1902319 GO:1902317 biolink:BiologicalProcess nuclear DNA replication termination Any DNA replication termination that is involved in nuclear cell cycle DNA replication. go-plus.json DNA replication termination involved in DNA replication during S phase|DNA replication termination involved in DNA replication involved in S phase|DNA replication termination involved in nuclear cell cycle DNA replication|DNA replication termination involved in DNA replication involved in S-phase http://purl.obolibrary.org/obo/GO_1902317 GO:1902318 biolink:BiologicalProcess synthesis of RNA primer involved in nuclear cell cycle DNA replication Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication. go-plus.json replication priming involved in DNA replication involved in S-phase|replication priming involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S phase|replication priming involved in nuclear cell cycle DNA replication|DNA replication, synthesis of RNA primer involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S-phase|replication priming involved in DNA replication involved in S phase http://purl.obolibrary.org/obo/GO_1902318 GO:1902315 biolink:BiologicalProcess nuclear cell cycle DNA replication initiation Any DNA replication initiation that is involved in nuclear cell cycle DNA replication. go-plus.json DNA replication initiation involved in nuclear cell cycle DNA replication|DNA endoreduplication initiation involved in nuclear cell cycle DNA replication|DNA re-replication initiation involved in nuclear cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902315 GO:1902316 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902316 GO:1902313 biolink:BiologicalProcess positive regulation of copper ion transmembrane transport Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport. go-plus.json positive regulation of copper ion membrane transport|up regulation of copper ion transmembrane transport|up-regulation of copper cation transmembrane transport|up-regulation of copper ion membrane transport|upregulation of copper ion transmembrane transport|upregulation of copper cation transmembrane transport|upregulation of copper ion membrane transport|up-regulation of copper ion transmembrane transport|activation of copper ion transmembrane transport|up regulation of copper cation transmembrane transport|activation of copper cation transmembrane transport|positive regulation of copper cation transmembrane transport|up regulation of copper ion membrane transport|activation of copper ion membrane transport http://purl.obolibrary.org/obo/GO_1902313 GO:1902314 biolink:MolecularActivity hydroquinone binding Binding to hydroquinone. go-plus.json quinol binding http://purl.obolibrary.org/obo/GO_1902314 GO:1902311 biolink:BiologicalProcess regulation of copper ion transmembrane transport Any process that modulates the frequency, rate or extent of copper ion transmembrane transport. go-plus.json regulation of copper cation transmembrane transport|regulation of copper ion membrane transport http://purl.obolibrary.org/obo/GO_1902311 GO:1902312 biolink:BiologicalProcess negative regulation of copper ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport. go-plus.json down-regulation of copper cation transmembrane transport|negative regulation of copper cation transmembrane transport|negative regulation of copper ion membrane transport|down-regulation of copper ion membrane transport|downregulation of copper ion transmembrane transport|inhibition of copper cation transmembrane transport|inhibition of copper ion membrane transport|down regulation of copper ion transmembrane transport|inhibition of copper ion transmembrane transport|down regulation of copper cation transmembrane transport|down regulation of copper ion membrane transport|downregulation of copper cation transmembrane transport|downregulation of copper ion membrane transport|down-regulation of copper ion transmembrane transport http://purl.obolibrary.org/obo/GO_1902312 GO:0060130 biolink:BiologicalProcess thyroid-stimulating hormone-secreting cell development The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. go-plus.json thyrotroph development|thyrotrope development|thyroid stimulating hormone secreting cell development|TSH-secreting cell development|beta-basophil development http://purl.obolibrary.org/obo/GO_0060130 GO:0060131 biolink:BiologicalProcess corticotropin hormone secreting cell development The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. go-plus.json corticotrophin hormone secreting cell development|corticotrope development|corticotroph development|adrenocorticotrophic hormone secreting cell development|adrenocorticotropic hormone secreting cell development http://purl.obolibrary.org/obo/GO_0060131 GO:1902310 biolink:BiologicalProcess positive regulation of peptidyl-serine dephosphorylation Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation. go-plus.json up regulation of peptidyl-serine dephosphorylation|activation of peptidyl-serine dephosphorylation|up-regulation of peptidyl-serine dephosphorylation|upregulation of peptidyl-serine dephosphorylation http://purl.obolibrary.org/obo/GO_1902310 GO:0060132 biolink:BiologicalProcess prolactin secreting cell development The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. go-plus.json mammotroph development|mammotropic cell development|mammotrope development|epsilon-acidophil development|lactotroph development|lactotropic cell development|lactotrope development|mammotrophic cell development http://purl.obolibrary.org/obo/GO_0060132 GO:0035122 biolink:BiologicalProcess embryonic medial fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. go-plus.json embryonic unpaired fin morphogenesis http://purl.obolibrary.org/obo/GO_0035122 GO:0060133 biolink:BiologicalProcess somatotropin secreting cell development The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. go-plus.json somatotrophin secreting cell development|somatrophic cell development|growth hormone secreting cell development|somatotropic cell development|somatotroph development|somatotrope development http://purl.obolibrary.org/obo/GO_0060133 GO:0060134 biolink:BiologicalProcess prepulse inhibition The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse. Wikipedia:Prepulse_inhibition go-plus.json PPI|pre-pulse inhibition http://purl.obolibrary.org/obo/GO_0060134 GO:0035123 biolink:BiologicalProcess embryonic dorsal fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. go-plus.json http://purl.obolibrary.org/obo/GO_0035123 GO:0035124 biolink:BiologicalProcess embryonic caudal fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035124 GO:0060135 biolink:BiologicalProcess maternal process involved in female pregnancy A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. go-plus.json http://purl.obolibrary.org/obo/GO_0060135 GO:0035125 biolink:BiologicalProcess embryonic anal fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. go-plus.json http://purl.obolibrary.org/obo/GO_0035125 GO:0060136 biolink:BiologicalProcess embryonic process involved in female pregnancy A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. go-plus.json http://purl.obolibrary.org/obo/GO_0060136 GO:0098709 biolink:BiologicalProcess glutathione import across plasma membrane The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json glutathione uptake|glutathione import into cell http://purl.obolibrary.org/obo/GO_0098709 GO:0035126 biolink:BiologicalProcess post-embryonic genitalia morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized. go-plus.json post-embryonic genital morphogenesis http://purl.obolibrary.org/obo/GO_0035126 GO:0060137 biolink:BiologicalProcess maternal process involved in parturition A reproductive process occurring in the mother that results in birth. go-plus.json http://purl.obolibrary.org/obo/GO_0060137 GO:0060138 biolink:BiologicalProcess fetal process involved in parturition A reproductive process occurring in the embryo that results in birth. go-plus.json http://purl.obolibrary.org/obo/GO_0060138 GO:0035127 biolink:BiologicalProcess post-embryonic limb morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. go-plus.json http://purl.obolibrary.org/obo/GO_0035127 GO:0060139 biolink:BiologicalProcess positive regulation of apoptotic process by virus Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process. go-plus.json positive regulation of apoptosis by virus http://purl.obolibrary.org/obo/GO_0060139 GO:0035128 biolink:BiologicalProcess post-embryonic forelimb morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0035128 GO:0098707 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098707 GO:0098708 biolink:BiologicalProcess glucose import across plasma membrane The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json high affinity glucose import|glucose import into cell http://purl.obolibrary.org/obo/GO_0098708 GO:0035129 biolink:BiologicalProcess post-embryonic hindlimb morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0035129 GO:0098705 biolink:BiologicalProcess copper ion import across plasma membrane The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json copper cation import into cell|high affinity copper ion transport|copper ion import into cell|high affinity copper transport|high-affinity copper ion transport http://purl.obolibrary.org/obo/GO_0098705 GO:0098706 biolink:BiologicalProcess iron ion import across cell outer membrane The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space. go-plus.json high-affinity ferric iron transmembrane transport|ferric iron transmembrane transport|ferric iron import across cell outer membrane|high affinity ferric iron transport|ferric ion import into cell|ferric iron import into cell http://purl.obolibrary.org/obo/GO_0098706 GO:0098703 biolink:BiologicalProcess calcium ion import across plasma membrane The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json calcium ion import into cell|calcium ion uptake into cell http://purl.obolibrary.org/obo/GO_0098703 GO:0098704 biolink:BiologicalProcess carbohydrate import across plasma membrane The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json carbohydrate import into cell http://purl.obolibrary.org/obo/GO_0098704 GO:0098701 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098701 GO:0098702 biolink:BiologicalProcess adenine import across plasma membrane The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json adenine import into cell http://purl.obolibrary.org/obo/GO_0098702 GO:0035120 biolink:BiologicalProcess post-embryonic appendage morphogenesis The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. go-plus.json http://purl.obolibrary.org/obo/GO_0035120 GO:0035121 biolink:BiologicalProcess obsolete tail morphogenesis OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals. go-plus.json tail morphogenesis http://purl.obolibrary.org/obo/GO_0035121 GO:0098700 biolink:BiologicalProcess neurotransmitter loading into synaptic vesicle The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps. go-plus.json neurotransmitter uptake into synaptic vesicle|neurotransmitter import into synaptic vesicle|synaptic vesicle neurotransmitter loading http://purl.obolibrary.org/obo/GO_0098700 goslim_synapse GO:1902328 biolink:BiologicalProcess bacterial-type DNA replication initiation Any DNA replication initiation that is involved in bacterial-type DNA replication. go-plus.json DNA replication initiation involved in bacterial-type DNA replication|DNA-dependent DNA replication initiation involved in bacterial-type DNA replication|DNA endoreduplication initiation involved in bacterial-type DNA replication|DNA re-replication initiation involved in bacterial-type DNA replication http://purl.obolibrary.org/obo/GO_1902328 GO:1902329 biolink:BiologicalProcess bacterial-type DNA replication termination Any DNA replication termination that is involved in bacterial-type DNA replication. go-plus.json DNA replication termination involved in bacterial-type DNA replication http://purl.obolibrary.org/obo/GO_1902329 GO:0035119 biolink:BiologicalProcess embryonic pelvic fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035119 GO:1902326 biolink:BiologicalProcess positive regulation of chlorophyll biosynthetic process Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process. go-plus.json up-regulation of chlorophyll anabolism|up-regulation of chlorophyll synthesis|positive regulation of chlorophyll biosynthesis|up regulation of chlorophyll biosynthetic process|up regulation of chlorophyll biosynthesis|up-regulation of chlorophyll formation|upregulation of chlorophyll anabolism|upregulation of chlorophyll synthesis|upregulation of chlorophyll formation|upregulation of chlorophyll biosynthesis|upregulation of chlorophyll biosynthetic process|up regulation of chlorophyll anabolism|activation of chlorophyll anabolism|positive regulation of chlorophyll anabolism|up regulation of chlorophyll synthesis|activation of chlorophyll synthesis|positive regulation of chlorophyll synthesis|up regulation of chlorophyll formation|up-regulation of chlorophyll biosynthetic process|up-regulation of chlorophyll biosynthesis|activation of chlorophyll biosynthesis|activation of chlorophyll biosynthetic process|activation of chlorophyll formation|positive regulation of chlorophyll formation http://purl.obolibrary.org/obo/GO_1902326 GO:1902327 biolink:BiologicalProcess bacterial-type DNA replication DNA ligation Any DNA ligation that is involved in bacterial-type DNA replication. go-plus.json DNA ligation involved in bacterial-type DNA replication http://purl.obolibrary.org/obo/GO_1902327 GO:1902324 biolink:BiologicalProcess positive regulation of methyl-branched fatty acid biosynthetic process Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process. go-plus.json upregulation of methyl-branched fatty acid formation|upregulation of methyl-branched fatty acid biosynthetic process|upregulation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid anabolism|activation of methyl-branched fatty acid anabolism|up-regulation of methyl-branched fatty acid synthesis|activation of methyl-branched fatty acid synthesis|up-regulation of methyl-branched fatty acid formation|activation of methyl-branched fatty acid formation|up regulation of methyl-branched fatty acid biosynthetic process|up regulation of methyl-branched fatty acid biosynthesis|positive regulation of methyl-branched fatty acid biosynthesis|activation of methyl-branched fatty acid biosynthesis|positive regulation of methyl-branched fatty acid anabolism|activation of methyl-branched fatty acid biosynthetic process|up regulation of methyl-branched fatty acid anabolism|positive regulation of methyl-branched fatty acid synthesis|up regulation of methyl-branched fatty acid synthesis|positive regulation of methyl-branched fatty acid formation|up regulation of methyl-branched fatty acid formation|up-regulation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid biosynthetic process|upregulation of methyl-branched fatty acid anabolism|upregulation of methyl-branched fatty acid synthesis http://purl.obolibrary.org/obo/GO_1902324 GO:1902325 biolink:BiologicalProcess negative regulation of chlorophyll biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process. go-plus.json inhibition of chlorophyll anabolism|down-regulation of chlorophyll formation|negative regulation of chlorophyll formation|down-regulation of chlorophyll biosynthetic process|down-regulation of chlorophyll biosynthesis|negative regulation of chlorophyll biosynthesis|inhibition of chlorophyll synthesis|inhibition of chlorophyll formation|downregulation of chlorophyll biosynthesis|downregulation of chlorophyll biosynthetic process|down regulation of chlorophyll anabolism|down regulation of chlorophyll biosynthesis|down regulation of chlorophyll biosynthetic process|inhibition of chlorophyll biosynthetic process|inhibition of chlorophyll biosynthesis|down regulation of chlorophyll synthesis|downregulation of chlorophyll anabolism|down regulation of chlorophyll formation|downregulation of chlorophyll synthesis|downregulation of chlorophyll formation|down-regulation of chlorophyll anabolism|negative regulation of chlorophyll anabolism|down-regulation of chlorophyll synthesis|negative regulation of chlorophyll synthesis http://purl.obolibrary.org/obo/GO_1902325 GO:1902322 biolink:BiologicalProcess regulation of methyl-branched fatty acid biosynthetic process Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process. go-plus.json regulation of methyl-branched fatty acid biosynthesis|regulation of methyl-branched fatty acid anabolism|regulation of methyl-branched fatty acid synthesis|regulation of methyl-branched fatty acid formation http://purl.obolibrary.org/obo/GO_1902322 GO:1902323 biolink:BiologicalProcess negative regulation of methyl-branched fatty acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process. go-plus.json down regulation of methyl-branched fatty acid biosynthetic process|down regulation of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid biosynthetic process|down-regulation of methyl-branched fatty acid anabolism|negative regulation of methyl-branched fatty acid anabolism|down-regulation of methyl-branched fatty acid synthesis|negative regulation of methyl-branched fatty acid synthesis|down-regulation of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid biosynthesis|down-regulation of methyl-branched fatty acid biosynthesis|down-regulation of methyl-branched fatty acid biosynthetic process|downregulation of methyl-branched fatty acid anabolism|down regulation of methyl-branched fatty acid anabolism|downregulation of methyl-branched fatty acid synthesis|inhibition of methyl-branched fatty acid biosynthetic process|inhibition of methyl-branched fatty acid biosynthesis|inhibition of methyl-branched fatty acid anabolism|downregulation of methyl-branched fatty acid formation|down regulation of methyl-branched fatty acid synthesis|inhibition of methyl-branched fatty acid synthesis|down regulation of methyl-branched fatty acid formation|inhibition of methyl-branched fatty acid formation http://purl.obolibrary.org/obo/GO_1902323 GO:1902320 biolink:BiologicalProcess nuclear DNA replication DNA duplex unwinding Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication. go-plus.json DNA duplex unwinding involved in nuclear cell cycle DNA replication|DNA duplex unwinding involved in DNA replication involved in S-phase|duplex DNA melting involved in DNA replication involved in S phase|DNA unwinding involved in DNA replication involved in S phase|DNA duplex unwinding involved in DNA replication during S phase|duplex DNA melting involved in DNA replication involved in S-phase|DNA unwinding involved in DNA replication involved in S-phase|DNA duplex unwinding involved in DNA replication involved in S phase|DNA unwinding involved in DNA replication during S phase|duplex DNA melting involved in DNA replication during S phase|DNA unwinding involved in nuclear cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902320 GO:0060120 biolink:BiologicalProcess inner ear receptor cell fate commitment The process in which a cell becomes committed to become an inner ear receptor cell. go-plus.json inner ear hair cell fate commitment http://purl.obolibrary.org/obo/GO_0060120 GO:1902321 biolink:BiologicalProcess methyl-branched fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid. go-plus.json methyl-branched fatty acid anabolism|methyl-branched fatty acid synthesis|methyl-branched fatty acid formation|methyl-branched fatty acid biosynthesis http://purl.obolibrary.org/obo/GO_1902321 GO:0060121 biolink:BiologicalProcess vestibular receptor cell stereocilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells. go-plus.json vestibular receptor cell stereocilium organisation|vestibular hair cell stereocilium organization|vestibular receptor cell stereocilium organization and biogenesis http://purl.obolibrary.org/obo/GO_0060121 GO:0060122 biolink:BiologicalProcess inner ear receptor cell stereocilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells. go-plus.json inner ear receptor stereocilium organisation|inner ear receptor stereocilium organization and biogenesis|inner ear hair cell receptor stereocilium organization http://purl.obolibrary.org/obo/GO_0060122 GO:0035111 biolink:BiologicalProcess obsolete leg joint morphogenesis OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur. go-plus.json leg joint morphogenesis http://purl.obolibrary.org/obo/GO_0035111 GO:0035112 biolink:BiologicalProcess genitalia morphogenesis The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. go-plus.json genital morphogenesis http://purl.obolibrary.org/obo/GO_0035112 GO:1902330 biolink:BiologicalProcess synthesis of RNA primer involved in bacterial-type DNA replication Any synthesis of RNA primer that is involved in bacterial-type DNA replication. go-plus.json replication priming involved in bacterial-type DNA replication http://purl.obolibrary.org/obo/GO_1902330 GO:0060123 biolink:BiologicalProcess regulation of growth hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060123 GO:0060124 biolink:BiologicalProcess positive regulation of growth hormone secretion Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060124 GO:0035113 biolink:BiologicalProcess embryonic appendage morphogenesis The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. go-plus.json http://purl.obolibrary.org/obo/GO_0035113 GO:0060125 biolink:BiologicalProcess negative regulation of growth hormone secretion Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060125 GO:0035114 biolink:BiologicalProcess imaginal disc-derived appendage morphogenesis The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0035114 GO:0060126 biolink:BiologicalProcess somatotropin secreting cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. go-plus.json somatotroph differentiation|somatotropic cell differentiation|somatotrope differentiation|somatotrophin secreting cell differentiation|somatrophic cell differentiation|growth hormone secreting cell differentiation http://purl.obolibrary.org/obo/GO_0060126 GO:0035115 biolink:BiologicalProcess embryonic forelimb morphogenesis The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. go-plus.json embryonic arm morphogenesis http://purl.obolibrary.org/obo/GO_0035115 GO:0035116 biolink:BiologicalProcess embryonic hindlimb morphogenesis The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal. go-plus.json http://purl.obolibrary.org/obo/GO_0035116 GO:0060127 biolink:BiologicalProcess prolactin secreting cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. go-plus.json mammotrophic cell differentiation|mammotroph differentiation|mammotropic cell differentiation|mammotrope differentiation|epsilon-acidophil differentiation|lactotroph differentiation|lactotropic cell differentiation|lactotrope differentiation http://purl.obolibrary.org/obo/GO_0060127 GO:0060128 biolink:BiologicalProcess corticotropin hormone secreting cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. go-plus.json adrenocorticotrophic hormone secreting cell differentiation|adrenocorticotropic hormone secreting cell differentiation|corticotroph differentiation|corticotrophin hormone secreting cell differentiation|corticotrope differentiation http://purl.obolibrary.org/obo/GO_0060128 GO:0098718 biolink:BiologicalProcess serine import across plasma membrane The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json serine import into cell http://purl.obolibrary.org/obo/GO_0098718 GO:0035117 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035117 GO:0098719 biolink:BiologicalProcess sodium ion import across plasma membrane The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json sodium ion import into cell|sodium ion import|sodium import http://purl.obolibrary.org/obo/GO_0098719 GO:0060129 biolink:BiologicalProcess thyroid-stimulating hormone-secreting cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin. go-plus.json thyroid stimulating hormone secreting cell differentiation|TSH-secreting cell differentiation|beta-basophil differentiation|thyrotroph differentiation|thyrotrope differentiation http://purl.obolibrary.org/obo/GO_0060129 GO:0035118 biolink:BiologicalProcess embryonic pectoral fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. go-plus.json http://purl.obolibrary.org/obo/GO_0035118 GO:0098716 biolink:BiologicalProcess nickel cation import across plasma membrane The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json nickel cation import into cell http://purl.obolibrary.org/obo/GO_0098716 GO:0098717 biolink:BiologicalProcess pantothenate import across plasma membrane The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json pantothenate import|pantothenate import into cell http://purl.obolibrary.org/obo/GO_0098717 GO:0098714 biolink:BiologicalProcess malate import across plasma membrane The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json malate import into cell http://purl.obolibrary.org/obo/GO_0098714 GO:0098715 biolink:BiologicalProcess malonic acid import across plasma membrane The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json malonic acid import into cell|malonate import into cell http://purl.obolibrary.org/obo/GO_0098715 GO:0098712 biolink:BiologicalProcess L-glutamate import across plasma membrane The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-glutamate(1-) import into cell|L-glutamate(1-) import across plasma membrane|L-glutamate import into cell http://purl.obolibrary.org/obo/GO_0098712 GO:0098713 biolink:BiologicalProcess leucine import across plasma membrane The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-leucine import into cell|leucine import into cell http://purl.obolibrary.org/obo/GO_0098713 GO:0098710 biolink:BiologicalProcess guanine import across plasma membrane The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json guanine import into cell http://purl.obolibrary.org/obo/GO_0098710 GO:0098711 biolink:BiologicalProcess iron ion import across plasma membrane The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json ferrous iron import across plasma membrane|iron ion import into cell|iron import into cell|ferrous iron import into cell|ferrous ion import into cell http://purl.obolibrary.org/obo/GO_0098711 GO:0035110 biolink:BiologicalProcess obsolete leg morphogenesis OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands. go-plus.json leg morphogenesis http://purl.obolibrary.org/obo/GO_0035110 GO:0098763 biolink:BiologicalProcess mitotic cell cycle phase One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. go-plus.json http://purl.obolibrary.org/obo/GO_0098763 gocheck_do_not_annotate GO:0098764 biolink:BiologicalProcess meiosis I cell cycle phase A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0098764 gocheck_do_not_annotate GO:0098761 biolink:BiologicalProcess cellular response to interleukin-7 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus. go-plus.json cellular response to IL-7 http://purl.obolibrary.org/obo/GO_0098761 GO:0098762 biolink:BiologicalProcess meiotic cell cycle phase One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. go-plus.json http://purl.obolibrary.org/obo/GO_0098762 gocheck_do_not_annotate GO:0098760 biolink:BiologicalProcess response to interleukin-7 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus. go-plus.json response to IL-7 http://purl.obolibrary.org/obo/GO_0098760 GO:1902339 biolink:BiologicalProcess positive regulation of apoptotic process involved in morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. go-plus.json up regulation of apoptosis involved in morphogenesis|positive regulation of apoptosis involved in morphogenesis|up-regulation of morphogenetic apoptosis|up regulation of apoptotic process involved in morphogenesis|upregulation of apoptosis involved in development|activation of apoptotic process involved in morphogenesis|activation of apoptosis involved in morphogenesis|upregulation of morphogenetic apoptosis|up-regulation of apoptosis involved in morphogenesis|up regulation of apoptosis involved in development|positive regulation of apoptosis involved in development|up-regulation of apoptotic process involved in morphogenesis|upregulation of apoptosis involved in morphogenesis|activation of apoptosis involved in development|up regulation of morphogenetic apoptosis|positive regulation of morphogenetic apoptosis|upregulation of apoptotic process involved in morphogenesis|up-regulation of apoptosis involved in development|activation of morphogenetic apoptosis http://purl.obolibrary.org/obo/GO_1902339 GO:1902337 biolink:BiologicalProcess regulation of apoptotic process involved in morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis. go-plus.json regulation of apoptosis involved in development|regulation of morphogenetic apoptosis|regulation of apoptosis involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 GO:0035108 biolink:BiologicalProcess limb morphogenesis The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping. go-plus.json limb bud morphogenesis http://purl.obolibrary.org/obo/GO_0035108 GO:1902338 biolink:BiologicalProcess negative regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. go-plus.json downregulation of apoptotic process involved in morphogenesis|inhibition of apoptosis involved in development|negative regulation of apoptosis involved in morphogenesis|down-regulation of apoptosis involved in morphogenesis|down regulation of apoptosis involved in development|inhibition of morphogenetic apoptosis|down-regulation of apoptotic process involved in morphogenesis|downregulation of apoptosis involved in development|down regulation of morphogenetic apoptosis|inhibition of apoptosis involved in morphogenesis|inhibition of apoptotic process involved in morphogenesis|downregulation of morphogenetic apoptosis|negative regulation of apoptosis involved in development|down-regulation of apoptosis involved in development|down regulation of apoptosis involved in morphogenesis|downregulation of apoptosis involved in morphogenesis|down-regulation of morphogenetic apoptosis|negative regulation of morphogenetic apoptosis|down regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902338 GO:0035109 biolink:BiologicalProcess obsolete imaginal disc-derived limb morphogenesis OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster. go-plus.json imaginal disc-derived limb morphogenesis http://purl.obolibrary.org/obo/GO_0035109 GO:1902335 biolink:BiologicalProcess obsolete positive chemotaxis involved in neuron migration OBSOLETE. Any positive chemotaxis that is involved in neuron migration. go-plus.json chemoattraction involved in neuron migration|positive chemotaxis involved in neuron migration|positive chemotaxis involved in neuron guidance|positive chemotaxis involved in neuron chemotaxis|positive chemotaxis involved in neuronal migration|chemoattraction involved in neuron chemotaxis|chemoattraction involved in neuron guidance|chemoattraction involved in neuronal migration http://purl.obolibrary.org/obo/GO_1902335 GO:1902336 biolink:BiologicalProcess positive regulation of retinal ganglion cell axon guidance Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance. go-plus.json up-regulation of retinal ganglion cell axon pathfinding|activation of retinal ganglion cell axon pathfinding|upregulation of retinal ganglion cell axon guidance|positive regulation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon guidance|activation of retinal ganglion cell axon guidance|upregulation of retinal ganglion cell axon pathfinding|up-regulation of retinal ganglion cell axon guidance http://purl.obolibrary.org/obo/GO_1902336 GO:0060150 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060150 GO:0060151 biolink:BiologicalProcess peroxisome localization Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. go-plus.json peroxisome localisation http://purl.obolibrary.org/obo/GO_0060151 GO:1902333 biolink:BiologicalProcess nuclear DNA replication DNA ligation Any DNA ligation that is involved in nuclear cell cycle DNA replication. go-plus.json DNA ligation involved in DNA replication during S phase|DNA ligation involved in DNA replication involved in S-phase|DNA ligation involved in nuclear cell cycle DNA replication|DNA ligation involved in DNA replication involved in S phase http://purl.obolibrary.org/obo/GO_1902333 GO:1902334 biolink:BiologicalProcess fructose export from vacuole to cytoplasm The directed movement of fructose from vacuole to cytoplasm. go-plus.json fructose transport from vacuole to cytoplasm http://purl.obolibrary.org/obo/GO_1902334 GO:0060152 biolink:BiologicalProcess microtubule-based peroxisome localization The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. go-plus.json microtubule-based peroxisome localisation http://purl.obolibrary.org/obo/GO_0060152 GO:0060153 biolink:BiologicalProcess modulation by virus of host cell cycle Any viral process that modulates the rate or extent of progression through the cell cycle. VZ:1636 go-plus.json regulation of host cell cycle by virus|modulation of host cell cycle by virus|regulation by virus of host cell cycle|viral process regulating host cell cycle http://purl.obolibrary.org/obo/GO_0060153 GO:1902331 biolink:BiologicalProcess obsolete DNA strand elongation involved in bacterial-type DNA replication OBSOLETE. Any DNA strand elongation that is involved in bacterial-type DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_1902331 GO:1902332 biolink:BiologicalProcess bacterial-type DNA replication DNA duplex unwinding Any DNA duplex unwinding that is involved in bacterial-type DNA replication. go-plus.json duplex DNA melting involved in bacterial-type DNA replication|DNA duplex unwinding involved in bacterial-type DNA replication|DNA unwinding involved in bacterial-type DNA replication http://purl.obolibrary.org/obo/GO_1902332 GO:0060154 biolink:BiologicalProcess obsolete cellular process regulating host cell cycle in response to virus OBSOLETE. Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus. go-plus.json http://purl.obolibrary.org/obo/GO_0060154 GO:1902340 biolink:BiologicalProcess negative regulation of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. go-plus.json down regulation of nuclear chromosome condensation|downregulation of nuclear chromosome condensation|down regulation of chromosome condensation|downregulation of chromosome condensation|negative regulation of eukaryotic chromosome condensation|down-regulation of eukaryotic chromosome condensation|negative regulation of nuclear chromosome condensation|down-regulation of nuclear chromosome condensation|inhibition of nuclear chromosome condensation|down-regulation of chromosome condensation|downregulation of eukaryotic chromosome condensation|down regulation of eukaryotic chromosome condensation|inhibition of eukaryotic chromosome condensation|inhibition of chromosome condensation http://purl.obolibrary.org/obo/GO_1902340 GO:0060155 biolink:BiologicalProcess platelet dense granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins. go-plus.json platelet dense granule organization and biogenesis|bull's eye body organization and biogenesis|platelet dense granule organisation|platelet dense body organization and biogenesis http://purl.obolibrary.org/obo/GO_0060155 GO:0035100 biolink:MolecularActivity ecdysone binding Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting. go-plus.json http://purl.obolibrary.org/obo/GO_0035100 GO:1902341 biolink:BiologicalProcess xylitol transport The directed movement of a xylitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose. go-plus.json http://purl.obolibrary.org/obo/GO_1902341 GO:0035101 biolink:CellularComponent FACT complex An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer. go-plus.json Facilitates chromatin transcription complex http://purl.obolibrary.org/obo/GO_0035101 GO:0060156 biolink:BiologicalProcess milk ejection reflex A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness. go-plus.json milk ejection http://purl.obolibrary.org/obo/GO_0060156 GO:0035102 biolink:CellularComponent PRC1 complex A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. go-plus.json Polycomb repressive complex 1 http://purl.obolibrary.org/obo/GO_0035102 GO:0060157 biolink:BiologicalProcess urinary bladder development The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion. go-plus.json http://purl.obolibrary.org/obo/GO_0060157 GO:0060158 biolink:BiologicalProcess phospholipase C-activating dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json activation of phospholipase C activity by dopamine receptor signalling pathway|activation of phospholipase C activity by dopamine receptor signaling pathway|dopamine receptor, phospholipase C activating pathway http://purl.obolibrary.org/obo/GO_0060158 GO:0035103 biolink:BiologicalProcess sterol regulatory element binding protein cleavage The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids. go-plus.json SREBP cleavage|sterol depletion response, SREBP cleavage|sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway http://purl.obolibrary.org/obo/GO_0035103 GO:0060159 biolink:BiologicalProcess regulation of dopamine receptor signaling pathway Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. go-plus.json regulation of dopamine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060159 GO:0035104 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035104 GO:0035105 biolink:BiologicalProcess obsolete sterol regulatory element binding protein import into nucleus OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes. go-plus.json SREBP import into nucleus|SREBP nuclear translocation|sterol regulatory element binding protein nuclear translocation|SREBP import into nucleus involved in sterol depletion response|sterol depletion response, sterol regulatory element binding protein import into nucleus|sterol depletion response, SREBP import into nucleus|sterol depletion response, sterol regulatory element binding protein nuclear translocation|sterol regulatory element binding protein import into nucleus involved in sterol depletion response|sterol regulatory element binding protein nuclear translocation involved in sterol depletion response|sterol depletion response, SREBP nuclear translocation http://purl.obolibrary.org/obo/GO_0035105 GO:0035106 biolink:BiologicalProcess operant conditioning Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior. Wikipedia:Operant_conditioning go-plus.json instrumental conditioning http://purl.obolibrary.org/obo/GO_0035106 OBO:uberon/core#indirectly_supplies biolink:OntologyClass indirectly_supplies a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s indirectly_supplies go-plus.json http://purl.obolibrary.org/obo/uberon/core#indirectly_supplies GO:0035107 biolink:BiologicalProcess appendage morphogenesis The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. go-plus.json http://purl.obolibrary.org/obo/GO_0035107 GO:0098769 biolink:MolecularActivity TIMP family protein binding Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family. go-plus.json http://purl.obolibrary.org/obo/GO_0098769 GO:0098767 biolink:BiologicalProcess obsolete meiosis II M phase OBSOLETE. M phase during meiosis II. go-plus.json http://purl.obolibrary.org/obo/GO_0098767 GO:0098768 biolink:BiologicalProcess meiotic prometaphase I The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate. go-plus.json http://purl.obolibrary.org/obo/GO_0098768 gocheck_do_not_annotate GO:0098765 biolink:BiologicalProcess meiosis II cell cycle phase A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division). go-plus.json http://purl.obolibrary.org/obo/GO_0098765 gocheck_do_not_annotate GO:0098766 biolink:BiologicalProcess obsolete meiosis I M phase OBSOLETE. M phase during meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0098766 GO:0098774 biolink:CellularComponent curli A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization. go-plus.json tafi|thin aggregative fimbrae http://purl.obolibrary.org/obo/GO_0098774 GO:0098775 biolink:BiologicalProcess curli assembly The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex. go-plus.json http://purl.obolibrary.org/obo/GO_0098775 GO:0098772 biolink:MolecularActivity molecular function regulator A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. go-plus.json http://purl.obolibrary.org/obo/GO_0098772 goslim_flybase_ribbon|gocheck_do_not_annotate GO:0098773 biolink:BiologicalProcess skin epidermis development The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0098773 GO:0098770 biolink:MolecularActivity FBXO family protein binding Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0098770 GO:0098771 biolink:BiologicalProcess inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098771 GO:1902348 biolink:BiologicalProcess cellular response to strigolactone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus. go-plus.json cellular response to strigolactone analog GR24 http://purl.obolibrary.org/obo/GO_1902348 GO:1902349 biolink:BiologicalProcess response to chloroquine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902349 GO:1902346 biolink:BiologicalProcess meiotic strand displacement involved in double-strand break repair via SDSA Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA). go-plus.json meiotic D-loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic displacement loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop processing involved in mitotic gene conversion|meiotic displacement loop processing involved in mitotic gene conversion|meiotic strand displacement involved in double-strand break repair via synthesis-dependent strand annealing|meiotic strand displacement involved in SDSA|meiotic displacement loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop dissociation involved in mitotic gene conversion|meiotic displacement loop dissociation involved in mitotic gene conversion|meiotic strand displacement involved in mitotic gene conversion http://purl.obolibrary.org/obo/GO_1902346 GO:1902347 biolink:BiologicalProcess response to strigolactone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus. go-plus.json response to strigolactone analog GR24 http://purl.obolibrary.org/obo/GO_1902347 GO:1902344 biolink:BiologicalProcess negative regulation of maltose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport. go-plus.json inhibition of maltose transport|down regulation of maltose transport|downregulation of maltose transport|down-regulation of maltose transport http://purl.obolibrary.org/obo/GO_1902344 GO:0060140 biolink:BiologicalProcess modulation by virus of syncytium formation via plasma membrane fusion The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060140 GO:1902345 biolink:BiologicalProcess positive regulation of maltose transport Any process that activates or increases the frequency, rate or extent of maltose transport. go-plus.json up-regulation of maltose transport|upregulation of maltose transport|up regulation of maltose transport|activation of maltose transport http://purl.obolibrary.org/obo/GO_1902345 GO:0060141 biolink:BiologicalProcess positive regulation of syncytium formation by virus The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. go-plus.json syncytium formation induced by viral infection http://purl.obolibrary.org/obo/GO_0060141 GO:0060142 biolink:BiologicalProcess regulation of syncytium formation by plasma membrane fusion Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060142 GO:1902342 biolink:BiologicalProcess xylitol export The directed movement of xylitol out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_1902342 GO:0060143 biolink:BiologicalProcess positive regulation of syncytium formation by plasma membrane fusion Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060143 GO:1902343 biolink:BiologicalProcess regulation of maltose transport Any process that modulates the frequency, rate or extent of maltose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1902343 GO:0060144 biolink:BiologicalProcess obsolete host cellular process involved in virus induced gene silencing OBSOLETE. A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes. go-plus.json http://purl.obolibrary.org/obo/GO_0060144 GO:1902351 biolink:BiologicalProcess response to imidacloprid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902351 GO:1902352 biolink:BiologicalProcess obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1902352 GO:0060145 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060145 GO:0060146 biolink:BiologicalProcess obsolete host gene silencing in virus induced gene silencing OBSOLETE. The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection. go-plus.json http://purl.obolibrary.org/obo/GO_0060146 GO:1902350 biolink:BiologicalProcess cellular response to chloroquine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902350 GO:0060147 biolink:BiologicalProcess regulation of posttranscriptional gene silencing Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0060147 GO:0060148 biolink:BiologicalProcess positive regulation of posttranscriptional gene silencing Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0060148 GO:0060149 biolink:BiologicalProcess negative regulation of posttranscriptional gene silencing Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0060149 GO:0098778 biolink:BiologicalProcess curli subunit secretion coupled to curli assembly The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface. go-plus.json extracellular nucleation-precipitation pathway http://purl.obolibrary.org/obo/GO_0098778 GO:0098779 biolink:BiologicalProcess positive regulation of mitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization. go-plus.json positive regulation of macromitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0098779 GO:0098776 biolink:BiologicalProcess protein transport across the cell outer membrane The directed movement of proteins across the cell outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098776 GO:0098777 biolink:BiologicalProcess protein secretion by the type VIII secretion system Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits. go-plus.json T8SS http://purl.obolibrary.org/obo/GO_0098777 GO:0098741 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098741 GO:0001796 biolink:BiologicalProcess regulation of type IIa hypersensitivity Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0001796 GO:0098742 biolink:BiologicalProcess cell-cell adhesion via plasma-membrane adhesion molecules The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098742 GO:0001797 biolink:BiologicalProcess negative regulation of type IIa hypersensitivity Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response. go-plus.json down-regulation of type IIa hypersensitivity|inhibition of type IIa hypersensitivity|down regulation of type IIa hypersensitivity|downregulation of type IIa hypersensitivity http://purl.obolibrary.org/obo/GO_0001797 GO:0001798 biolink:BiologicalProcess positive regulation of type IIa hypersensitivity Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response. go-plus.json up regulation of type IIa hypersensitivity|activation of type IIa hypersensitivity|stimulation of type IIa hypersensitivity|up-regulation of type IIa hypersensitivity|upregulation of type IIa hypersensitivity http://purl.obolibrary.org/obo/GO_0001798 GO:0098740 biolink:BiologicalProcess obsolete multi organism cell adhesion OBSOLETE. Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0098740 GO:0001799 biolink:BiologicalProcess regulation of type IIb hypersensitivity Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0001799 GO:0001792 biolink:MolecularActivity polymeric immunoglobulin receptor activity Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001792 CHEBI:144897 biolink:ChemicalSubstance 1-piperideinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_144897 chebi_ph7_3 GO:0001793 biolink:MolecularActivity IgM receptor activity Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0001793 GO:0001794 biolink:BiologicalProcess type IIa hypersensitivity An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell. go-plus.json http://purl.obolibrary.org/obo/GO_0001794 GO:0001795 biolink:BiologicalProcess type IIb hypersensitivity An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors. go-plus.json type V hypersensitivity http://purl.obolibrary.org/obo/GO_0001795 GO:1902359 biolink:BiologicalProcess Notch signaling pathway involved in somitogenesis Any Notch signaling pathway that is involved in somitogenesis. go-plus.json Notch receptor signaling pathway involved in somitogenesis|Notch receptor signalling pathway involved in somitogenesis|Notch signalling pathway involved in formation of mesodermal clusters|N signaling pathway involved in formation of mesodermal clusters|Notch-receptor signaling pathway involved in formation of mesodermal clusters|Notch-receptor signalling pathway involved in formation of mesodermal clusters|N signalling pathway involved in somitogenesis|N signalling pathway involved in formation of mesodermal clusters|Notch signaling pathway involved in formation of mesodermal clusters|Notch-receptor signalling pathway involved in somitogenesis|Notch-receptor signaling pathway involved in somitogenesis|N signaling pathway involved in somitogenesis|Notch signalling pathway involved in somitogenesis|Notch receptor signalling pathway involved in formation of mesodermal clusters|Notch receptor signaling pathway involved in formation of mesodermal clusters http://purl.obolibrary.org/obo/GO_1902359 GO:0060170 biolink:CellularComponent ciliary membrane The portion of the plasma membrane surrounding a cilium. go-plus.json cilium membrane|flagellar membrane|flagellum membrane|cilial membrane http://purl.obolibrary.org/obo/GO_0060170 GO:0001790 biolink:MolecularActivity polymeric immunoglobulin binding Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes. go-plus.json http://purl.obolibrary.org/obo/GO_0001790 GO:0060171 biolink:CellularComponent stereocilium membrane The portion of the plasma membrane surrounding a stereocilium. go-plus.json http://purl.obolibrary.org/obo/GO_0060171 GO:1902357 biolink:BiologicalProcess 2-isopropylmalate(2-) transmembrane transport The process in which 2-isopropylmalate(2-) is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902357 GO:0001791 biolink:MolecularActivity IgM binding Binding to an immunoglobulin of the IgM isotype. go-plus.json http://purl.obolibrary.org/obo/GO_0001791 GO:1902358 biolink:BiologicalProcess sulfate transmembrane transport The directed movement of sulfate across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902358 GO:0060172 biolink:BiologicalProcess astral microtubule depolymerization The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060172 GO:1902355 biolink:BiologicalProcess endothelial tube lumen extension involved in blood vessel lumen ensheathment Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment. go-plus.json http://purl.obolibrary.org/obo/GO_1902355 GO:0060173 biolink:BiologicalProcess limb development The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. Wikipedia:Limb_development go-plus.json limb bud development|paired limb/fin development http://purl.obolibrary.org/obo/GO_0060173 GO:0060174 biolink:BiologicalProcess limb bud formation The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. go-plus.json limb formation|limbbud formation http://purl.obolibrary.org/obo/GO_0060174 GO:1902356 biolink:BiologicalProcess oxaloacetate(2-) transmembrane transport The directed movement of oxaloacetate(2-) across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902356 GO:0060175 biolink:MolecularActivity brain-derived neurotrophic factor-activated receptor activity Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json brain-derived neurotrophic factor receptor activity|BDNF receptor activity|BDNF-activated receptor activity http://purl.obolibrary.org/obo/GO_0060175 GO:1902353 biolink:BiologicalProcess obsolete positive regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter by pheromones that results in positive regulation of induction of conjugation with cellular fusion. go-plus.json up regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|up-regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|upregulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones http://purl.obolibrary.org/obo/GO_1902353 GO:1902354 biolink:BiologicalProcess blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment. go-plus.json http://purl.obolibrary.org/obo/GO_1902354 GO:0060176 biolink:BiologicalProcess regulation of aggregation involved in sorocarp development Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. go-plus.json http://purl.obolibrary.org/obo/GO_0060176 NCBITaxon:227377 biolink:OrganismalEntity Coxiella burnetii RSA 493 go-plus.json Coxiella burnetii str. RSA 493 http://purl.obolibrary.org/obo/NCBITaxon_227377 GO:1902362 biolink:BiologicalProcess melanocyte apoptotic process Any apoptotic process in a melanocyte, the main structural component of the epidermis. go-plus.json melanophore apoptotic process|melanophore apoptosis|melanocyte apoptosis http://purl.obolibrary.org/obo/GO_1902362 GO:0060177 biolink:BiologicalProcess regulation of angiotensin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin. go-plus.json regulation of angiotensin metabolism http://purl.obolibrary.org/obo/GO_0060177 GO:1902363 biolink:BiologicalProcess regulation of protein localization to spindle pole body Any process that modulates the frequency, rate or extent of protein localization to spindle pole body. go-plus.json regulation of protein localisation to spindle pole body http://purl.obolibrary.org/obo/GO_1902363 GO:0060178 biolink:BiologicalProcess regulation of exocyst localization Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. go-plus.json regulation of exocyst localisation http://purl.obolibrary.org/obo/GO_0060178 GO:0060179 biolink:BiologicalProcess male mating behavior The specific behavior of a male organism that is associated with reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0060179 GO:1902360 biolink:BiologicalProcess conversion of ds siRNA to ss siRNA involved in gene silencing by small RNA Any conversion of ds siRNA to ss siRNA that is involved in gene silencing by small RNA. go-plus.json conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA interference-like chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNA-mediated transcriptional silencing|conversion of ds siRNA to ss siRNA involved in chromatin silencing by small RNA|conversion of ds siRNA to ss siRNA involved in RNAi-directed chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in chromatin silencing by small RNA|conversion of ds siRNA to ss siRNA involved in RNA interference-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in small RNA-mediated heterochromatic silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNAi-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-directed chromatin silencing|conversion of ds siRNA to ss siRNA involved in small RNA-mediated heterochromatic silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated transcriptional silencing|conversion of ds siRNA to ss siRNA involved in RNA-mediated chromatin silencing http://purl.obolibrary.org/obo/GO_1902360 GO:1902361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902361 GO:0098749 biolink:BiologicalProcess cerebellar neuron development The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098749 GO:0098747 biolink:BiologicalProcess slow, calcium ion-dependent exocytosis of neurotransmitter The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release. go-plus.json http://purl.obolibrary.org/obo/GO_0098747 GO:0098748 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098748 GO:0098745 biolink:CellularComponent Dcp1-Dcp2 complex A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0098745 GO:0098746 biolink:BiologicalProcess fast, calcium ion-dependent exocytosis of neurotransmitter The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release. go-plus.json synchronous, calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_0098746 GO:0098743 biolink:BiologicalProcess cell aggregation The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation. go-plus.json http://purl.obolibrary.org/obo/GO_0098743 GO:0098744 biolink:MolecularActivity 1-phosphatidylinositol 4-kinase activator activity Binds to and increases the activity of 1-phosphatidylinositol 4-kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0098744 GO:0098752 biolink:CellularComponent integral component of the cytoplasmic side of the plasma membrane The component of the plasma membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098752 GO:0098753 biolink:CellularComponent anchored component of the cytoplasmic side of the plasma membrane The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098753 GO:0098750 biolink:MolecularActivity FYXD domain binding Binding to a FXYD domain. go-plus.json http://purl.obolibrary.org/obo/GO_0098750 GO:0098751 biolink:BiologicalProcess bone cell development The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098751 gocheck_do_not_annotate GO:2001303 biolink:BiologicalProcess lipoxin A4 biosynthetic process The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. go-plus.json lipoxin A4 biosynthesis|LXA4 anabolism|LXA4 synthesis|LXA4 formation|LXA4 biosynthetic process|LXA4 biosynthesis|lipoxin A4 anabolism|lipoxin A4 synthesis|lipoxin A4 formation http://purl.obolibrary.org/obo/GO_2001303 GO:2001304 biolink:BiologicalProcess lipoxin B4 metabolic process The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. go-plus.json lipoxin B4 metabolism|LXB4 metabolism|LXB4 metabolic process http://purl.obolibrary.org/obo/GO_2001304 GO:0060160 biolink:BiologicalProcess negative regulation of dopamine receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. go-plus.json negative regulation of dopamine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060160 GO:2001305 biolink:BiologicalProcess xanthone-containing compound metabolic process The chemical reactions and pathways involving a xanthone-containing compound. go-plus.json xanthone metabolism|xanthone-containing compound metabolism|xanthones metabolic process|xanthones metabolism http://purl.obolibrary.org/obo/GO_2001305 GO:1902368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902368 GO:1902369 biolink:BiologicalProcess negative regulation of RNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. go-plus.json negative regulation of RNA breakdown|negative regulation of RNA catabolism|down-regulation of RNA breakdown|down-regulation of RNA catabolism|inhibition of RNA degradation|down-regulation of RNA catabolic process|inhibition of RNA breakdown|downregulation of RNA catabolism|inhibition of RNA catabolic process|down regulation of RNA catabolism|inhibition of RNA catabolism|down regulation of RNA degradation|downregulation of RNA degradation|down regulation of RNA breakdown|down regulation of RNA catabolic process|downregulation of RNA breakdown|down-regulation of RNA degradation|negative regulation of RNA degradation|downregulation of RNA catabolic process http://purl.obolibrary.org/obo/GO_1902369 GO:0060161 biolink:BiologicalProcess positive regulation of dopamine receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. go-plus.json positive regulation of dopamine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060161 GO:2001306 biolink:BiologicalProcess lipoxin B4 biosynthetic process The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. go-plus.json lipoxin B4 biosynthesis|LXB4 anabolism|LXB4 synthesis|LXB4 formation|LXB4 biosynthesis|LXB4 biosynthetic process|lipoxin B4 anabolism|lipoxin B4 synthesis|lipoxin B4 formation http://purl.obolibrary.org/obo/GO_2001306 GO:1902366 biolink:BiologicalProcess regulation of Notch signaling pathway involved in somitogenesis Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis. go-plus.json regulation of N signaling pathway involved in formation of mesodermal clusters|regulation of Notch receptor signalling pathway involved in somitogenesis|regulation of Notch signalling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|regulation of N signalling pathway involved in somitogenesis|regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|regulation of Notch signaling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signaling pathway involved in somitogenesis|regulation of N signalling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signalling pathway involved in somitogenesis|regulation of Notch signalling pathway involved in somitogenesis|regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|regulation of N signaling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters http://purl.obolibrary.org/obo/GO_1902366 GO:2001307 biolink:BiologicalProcess xanthone-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a xanthone-containing compound. go-plus.json xanthones anabolism|xanthones synthesis|xanthones formation|xanthone-containing compound anabolism|xanthone biosynthesis|xanthone biosynthetic process|xanthone-containing compound synthesis|xanthone-containing compound biosynthesis|xanthone-containing compound formation|xanthones biosynthesis|xanthones biosynthetic process http://purl.obolibrary.org/obo/GO_2001307 GO:0060162 biolink:BiologicalProcess negative regulation of phospholipase C-activating dopamine receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway. go-plus.json negative regulation of dopamine receptor, phospholipase C activating pathway|negative regulation of phospholipase C-activating dopamine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060162 GO:1902367 biolink:BiologicalProcess negative regulation of Notch signaling pathway involved in somitogenesis Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis. go-plus.json downregulation of N signaling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch signaling pathway involved in formation of mesodermal clusters|inhibition of N signalling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in somitogenesis|down-regulation of N signaling pathway involved in somitogenesis|negative regulation of Notch-receptor signaling pathway involved in somitogenesis|down-regulation of Notch-receptor signaling pathway involved in somitogenesis|down regulation of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch signalling pathway involved in formation of mesodermal clusters|down regulation of N signaling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|inhibition of N signaling pathway involved in formation of mesodermal clusters|downregulation of N signalling pathway involved in somitogenesis|downregulation of Notch receptor signalling pathway involved in somitogenesis|downregulation of Notch signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch signalling pathway involved in somitogenesis|down-regulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of N signaling pathway involved in somitogenesis|down-regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in formation of mesodermal clusters|down regulation of Notch signaling pathway involved in somitogenesis|down regulation of N signalling pathway involved in somitogenesis|inhibition of Notch-receptor signalling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signaling pathway involved in somitogenesis|inhibition of N signalling pathway involved in somitogenesis|downregulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down regulation of N signalling pathway involved in formation of mesodermal clusters|down regulation of Notch signaling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in somitogenesis|down regulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch-receptor signaling pathway involved in somitogenesis|down-regulation of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signalling pathway involved in somitogenesis|negative regulation of Notch receptor signaling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signaling pathway involved in somitogenesis|downregulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch signalling pathway involved in formation of mesodermal clusters|downregulation of N signalling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signaling pathway involved in somitogenesis|downregulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch signalling pathway involved in somitogenesis|down regulation of N signaling pathway involved in somitogenesis|down regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in formation of mesodermal clusters|down-regulation of N signaling pathway involved in formation of mesodermal clusters|inhibition of Notch signalling pathway involved in somitogenesis|inhibition of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of Notch signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch signaling pathway involved in somitogenesis|downregulation of N signaling pathway involved in somitogenesis|downregulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of N signalling pathway involved in formation of mesodermal clusters|negative regulation of N signalling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in somitogenesis|inhibition of Notch-receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of N signalling pathway involved in somitogenesis|negative regulation of N signalling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in somitogenesis http://purl.obolibrary.org/obo/GO_1902367 GO:0060163 biolink:BiologicalProcess subpallium neuron fate commitment The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon. go-plus.json subpallium neuronal precursor fate commitment http://purl.obolibrary.org/obo/GO_0060163 GO:2001308 biolink:BiologicalProcess gliotoxin metabolic process The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi. go-plus.json gliotoxin metabolism http://purl.obolibrary.org/obo/GO_2001308 GO:2001309 biolink:BiologicalProcess gliotoxin catabolic process The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi. go-plus.json gliotoxin degradation|gliotoxin catabolism|gliotoxin breakdown http://purl.obolibrary.org/obo/GO_2001309 GO:1902364 biolink:BiologicalProcess negative regulation of protein localization to spindle pole body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body. go-plus.json inhibition of protein localization to spindle pole body|negative regulation of protein localisation to spindle pole body|down-regulation of protein localisation to spindle pole body|inhibition of protein localisation to spindle pole body|down regulation of protein localization to spindle pole body|downregulation of protein localization to spindle pole body|down regulation of protein localisation to spindle pole body|downregulation of protein localisation to spindle pole body|down-regulation of protein localization to spindle pole body http://purl.obolibrary.org/obo/GO_1902364 GO:0060164 biolink:BiologicalProcess regulation of timing of neuron differentiation The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0060164 GO:1902365 biolink:BiologicalProcess positive regulation of protein localization to spindle pole body Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body. go-plus.json up-regulation of protein localization to spindle pole body|up-regulation of protein localisation to spindle pole body|upregulation of protein localization to spindle pole body|upregulation of protein localisation to spindle pole body|up regulation of protein localization to spindle pole body|activation of protein localization to spindle pole body|up regulation of protein localisation to spindle pole body|activation of protein localisation to spindle pole body|positive regulation of protein localisation to spindle pole body http://purl.obolibrary.org/obo/GO_1902365 GO:0060165 biolink:BiologicalProcess regulation of timing of subpallium neuron differentiation The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon. go-plus.json http://purl.obolibrary.org/obo/GO_0060165 GO:1902373 biolink:BiologicalProcess negative regulation of mRNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process. go-plus.json downregulation of mRNA degradation|down-regulation of mRNA catabolic process|inhibition of mRNA catabolism|down regulation of mRNA degradation|downregulation of mRNA breakdown|inhibition of mRNA degradation|negative regulation of mRNA decay|down-regulation of mRNA decay|down regulation of mRNA breakdown|downregulation of mRNA catabolic process|inhibition of mRNA breakdown|down regulation of mRNA catabolism|down regulation of mRNA catabolic process|inhibition of mRNA catabolic process|downregulation of mRNA catabolism|downregulation of mRNA decay|down regulation of mRNA decay|negative regulation of mRNA degradation|down-regulation of mRNA degradation|negative regulation of mRNA catabolism|down-regulation of mRNA catabolism|down-regulation of mRNA breakdown|negative regulation of mRNA breakdown|inhibition of mRNA decay http://purl.obolibrary.org/obo/GO_1902373 GO:0060166 biolink:BiologicalProcess olfactory pit development The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx. go-plus.json http://purl.obolibrary.org/obo/GO_0060166 GO:0060167 biolink:BiologicalProcess regulation of adenosine receptor signaling pathway Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands. go-plus.json regulation of adenosine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060167 GO:1902374 biolink:BiologicalProcess regulation of rRNA catabolic process Any process that modulates the frequency, rate or extent of rRNA catabolic process. go-plus.json regulation of rRNA degradation|regulation of rRNA catabolism|regulation of rRNA breakdown http://purl.obolibrary.org/obo/GO_1902374 GO:1902371 biolink:BiologicalProcess negative regulation of tRNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process. go-plus.json down-regulation of tRNA breakdown|negative regulation of tRNA breakdown|down regulation of tRNA catabolism|downregulation of tRNA degradation|down-regulation of tRNA catabolic process|downregulation of tRNA catabolism|down regulation of tRNA degradation|downregulation of tRNA breakdown|inhibition of tRNA degradation|downregulation of tRNA catabolic process|down regulation of tRNA breakdown|inhibition of tRNA breakdown|down-regulation of tRNA catabolism|negative regulation of tRNA catabolism|down regulation of tRNA catabolic process|inhibition of tRNA catabolic process|inhibition of tRNA catabolism|negative regulation of tRNA degradation|down-regulation of tRNA degradation http://purl.obolibrary.org/obo/GO_1902371 GO:0060168 biolink:BiologicalProcess positive regulation of adenosine receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands. go-plus.json positive regulation of adenosine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060168 GO:1902372 biolink:BiologicalProcess positive regulation of tRNA catabolic process Any process that activates or increases the frequency, rate or extent of tRNA catabolic process. go-plus.json activation of tRNA catabolic process|up-regulation of tRNA catabolic process|positive regulation of tRNA degradation|upregulation of tRNA catabolism|up regulation of tRNA degradation|positive regulation of tRNA breakdown|up regulation of tRNA breakdown|up regulation of tRNA catabolism|up regulation of tRNA catabolic process|activation of tRNA catabolism|upregulation of tRNA degradation|positive regulation of tRNA catabolism|upregulation of tRNA breakdown|up-regulation of tRNA degradation|upregulation of tRNA catabolic process|activation of tRNA degradation|up-regulation of tRNA catabolism|activation of tRNA breakdown|up-regulation of tRNA breakdown http://purl.obolibrary.org/obo/GO_1902372 GO:0060169 biolink:BiologicalProcess negative regulation of adenosine receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands. go-plus.json negative regulation of adenosine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060169 GO:1902370 biolink:BiologicalProcess regulation of tRNA catabolic process Any process that modulates the frequency, rate or extent of tRNA catabolic process. go-plus.json regulation of tRNA catabolism|regulation of tRNA degradation|regulation of tRNA breakdown http://purl.obolibrary.org/obo/GO_1902370 GO:2001300 biolink:BiologicalProcess lipoxin metabolic process The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid. go-plus.json lipoxin metabolism http://purl.obolibrary.org/obo/GO_2001300 GO:2001301 biolink:BiologicalProcess lipoxin biosynthetic process The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid. go-plus.json lipoxin anabolism|lipoxin synthesis|lipoxin formation|lipoxin biosynthesis http://purl.obolibrary.org/obo/GO_2001301 GO:2001302 biolink:BiologicalProcess lipoxin A4 metabolic process The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. go-plus.json lipoxin A4 metabolism|LXA4 metabolism|LXA4 metabolic process http://purl.obolibrary.org/obo/GO_2001302 GO:0098758 biolink:BiologicalProcess response to interleukin-8 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus. go-plus.json response to IL-8 http://purl.obolibrary.org/obo/GO_0098758 GO:0098759 biolink:BiologicalProcess cellular response to interleukin-8 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus. go-plus.json cellular response to IL-8 http://purl.obolibrary.org/obo/GO_0098759 GO:0098756 biolink:BiologicalProcess response to interleukin-21 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus. go-plus.json response to IL-21 http://purl.obolibrary.org/obo/GO_0098756 GO:0098757 biolink:BiologicalProcess cellular response to interleukin-21 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus. go-plus.json cellular response to IL-21 http://purl.obolibrary.org/obo/GO_0098757 GO:0098754 biolink:BiologicalProcess detoxification Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. go-plus.json http://purl.obolibrary.org/obo/GO_0098754 goslim_pombe GO:0098755 biolink:BiologicalProcess maintenance of seed dormancy by absisic acid The process by which seed dormancy is maintained by the presence of absisic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0098755 GO:0050701 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050701 GO:0050702 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050702 GO:0050700 biolink:MolecularActivity CARD domain binding Binding to a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family. go-plus.json http://purl.obolibrary.org/obo/GO_0050700 GO:0050705 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050705 NCBITaxon:50827 biolink:OrganismalEntity Diplogasteromorpha go-plus.json Diplogasterida http://purl.obolibrary.org/obo/NCBITaxon_50827 GO:0050706 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050706 GO:0050703 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050703 CHEBI:62480 biolink:ChemicalSubstance spheroiden-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_62480 chebi_ph7_3 CHEBI:62481 biolink:ChemicalSubstance (3E)-3,4-didehydrorhodopin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62481 chebi_ph7_3 GO:0050704 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050704 GO:0050709 biolink:BiologicalProcess negative regulation of protein secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. go-plus.json down-regulation of protein secretion|inhibition of protein secretion|down regulation of protein secretion|downregulation of protein secretion http://purl.obolibrary.org/obo/GO_0050709 GO:0050707 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050707 GO:0050708 biolink:BiologicalProcess regulation of protein secretion Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0050708 CHEBI:86457 biolink:ChemicalSubstance 2-hydroxybenzoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_86457 CHEBI:86458 biolink:ChemicalSubstance 2-hydroxybenzoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86458 chebi_ph7_3 CHEBI:86459 biolink:ChemicalSubstance (R)-lipoyl-GMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_86459 CHEBI:62488 biolink:ChemicalSubstance signalling molecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_62488 GO:0050712 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050712 CHEBI:62490 biolink:ChemicalSubstance sphingomyelin d18:1(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62490 GO:0050713 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050713 GO:0050710 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050710 GO:0050711 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050711 GO:0050716 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050716 GO:0050717 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050717 GO:0050714 biolink:BiologicalProcess positive regulation of protein secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. go-plus.json upregulation of protein secretion|up regulation of protein secretion|activation of protein secretion|stimulation of protein secretion|up-regulation of protein secretion http://purl.obolibrary.org/obo/GO_0050714 GO:0050715 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050715 CHEBI:86441 biolink:ChemicalSubstance (2E)-pentenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86441 CHEBI:62497 biolink:ChemicalSubstance 7-(3-methylbut-2-enyl)-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62497 chebi_ph7_3 CHEBI:62495 biolink:ChemicalSubstance D-glucosylsphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62495 chebi_ph7_3 GO:0050718 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050718 NCBITaxon:227321 biolink:OrganismalEntity Aspergillus nidulans FGSC A4 go-plus.json Emericella nidulans FGSC A4 http://purl.obolibrary.org/obo/NCBITaxon_227321 GO:0050719 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050719 CHEBI:62499 biolink:ChemicalSubstance methyl-branched fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62499 GO:0050720 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050720 GO:0050723 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050723 GO:0050724 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050724 GO:0050721 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050721 GO:0050722 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050722 GO:0050727 biolink:BiologicalProcess regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. go-plus.json http://purl.obolibrary.org/obo/GO_0050727 GO:0050728 biolink:BiologicalProcess negative regulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. go-plus.json down-regulation of inflammatory response|inhibition of inflammatory response|anti-inflammatory response|down regulation of inflammatory response|downregulation of inflammatory response http://purl.obolibrary.org/obo/GO_0050728 GO:0050725 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050725 GO:0050726 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050726 GO:0050729 biolink:BiologicalProcess positive regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of the inflammatory response. go-plus.json up regulation of inflammatory response|activation of inflammatory response|stimulation of inflammatory response|up-regulation of inflammatory response|upregulation of inflammatory response http://purl.obolibrary.org/obo/GO_0050729 CHEBI:86478 biolink:ChemicalSubstance antibiotic antifungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_86478 GO:0050730 biolink:BiologicalProcess regulation of peptidyl-tyrosine phosphorylation Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. go-plus.json http://purl.obolibrary.org/obo/GO_0050730 GO:0050731 biolink:BiologicalProcess positive regulation of peptidyl-tyrosine phosphorylation Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. go-plus.json up regulation of peptidyl-tyrosine phosphorylation|activation of peptidyl-tyrosine phosphorylation|stimulation of peptidyl-tyrosine phosphorylation|up-regulation of peptidyl-tyrosine phosphorylation|upregulation of peptidyl-tyrosine phosphorylation http://purl.obolibrary.org/obo/GO_0050731 GO:0050734 biolink:MolecularActivity hydroxycinnamoyltransferase activity Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0050734 GO:0050735 biolink:MolecularActivity N-malonyltransferase activity Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0050735 GO:0050732 biolink:BiologicalProcess negative regulation of peptidyl-tyrosine phosphorylation Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. go-plus.json down-regulation of peptidyl-tyrosine phosphorylation|inhibition of peptidyl-tyrosine phosphorylation|down regulation of peptidyl-tyrosine phosphorylation|downregulation of peptidyl-tyrosine phosphorylation http://purl.obolibrary.org/obo/GO_0050732 GO:0050733 biolink:MolecularActivity RS domain binding Binding to an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing. go-plus.json http://purl.obolibrary.org/obo/GO_0050733 GO:0050738 biolink:MolecularActivity fructosyltransferase activity Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0050738 CHEBI:86460 biolink:ChemicalSubstance (R)-lipoyl-GMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86460 chebi_ph7_3 GO:0050739 biolink:BiologicalProcess peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium. RESID:AA0348 go-plus.json http://purl.obolibrary.org/obo/GO_0050739 GO:0050736 biolink:MolecularActivity O-malonyltransferase activity Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0050736 CHEBI:86462 biolink:ChemicalSubstance O-(S-2-hydroxybenzoylpantetheine-4'-phosphoryl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86462 GO:0050737 biolink:MolecularActivity O-hydroxycinnamoyltransferase activity Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0050737 CHEBI:86464 biolink:ChemicalSubstance O-(S-2-hydroxybenzoylpantetheine-4'-phosphoryl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86464 chebi_ph7_3 GO:0035199 biolink:BiologicalProcess salt aversion The specific avoidance actions or reactions of an organism in response to the perception of salt. go-plus.json behavioral response to salt http://purl.obolibrary.org/obo/GO_0035199 CHEBI:86468 biolink:ChemicalSubstance dimethylarginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86468 CHEBI:86469 biolink:ChemicalSubstance peptidoglycosaminoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_86469 GO:0035191 biolink:BiologicalProcess nuclear axial expansion The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex. go-plus.json nuclear distribution along anterior-posterior axis|nucleus distribution along anterior-posterior axis http://purl.obolibrary.org/obo/GO_0035191 GO:0035192 biolink:BiologicalProcess nuclear cortical migration The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0035192 GO:0035193 biolink:BiologicalProcess larval central nervous system remodeling Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster. go-plus.json central nervous system metamorphosis|CNS metamorphosis http://purl.obolibrary.org/obo/GO_0035193 GO:0035194 biolink:BiologicalProcess post-transcriptional gene silencing by RNA Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation. go-plus.json RNA-mediated posttranscriptional gene silencing|sense-PTGS|posttranscriptional gene silencing by RNA http://purl.obolibrary.org/obo/GO_0035194 GO:0035195 biolink:BiologicalProcess gene silencing by miRNA Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. go-plus.json microRNA-mediated gene silencing|gene silencing by microRNA|miRNA-mediated gene silencing http://purl.obolibrary.org/obo/GO_0035195 GO:0035196 biolink:BiologicalProcess production of miRNAs involved in gene silencing by miRNA Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts. go-plus.json microRNA metabolic process|microRNA biogenesis|miRNA biogenesis|miRNA-mediated gene silencing, production of miRNAs|miRNA processing|gene silencing by miRNA, production of miRNAs|microRNA processing|microRNA biosynthesis|microRNA biosynthetic process|microRNA-mediated gene silencing, production of microRNAs|microRNA metabolism|production of microRNAs involved in gene silencing by microRNA http://purl.obolibrary.org/obo/GO_0035196 GO:0035197 biolink:MolecularActivity siRNA binding Binding to a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme. go-plus.json small interfering RNA binding http://purl.obolibrary.org/obo/GO_0035197 GO:0035198 biolink:MolecularActivity miRNA binding Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes. go-plus.json microRNA binding http://purl.obolibrary.org/obo/GO_0035198 GO:0050741 biolink:BiologicalProcess protein-FMN linkage via O3-riboflavin phosphoryl-L-serine The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine. RESID:AA0350 go-plus.json http://purl.obolibrary.org/obo/GO_0050741 GO:0050742 biolink:BiologicalProcess protein-FMN linkage via S-(4a-FMN)-L-cysteine The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine. RESID:AA0351 go-plus.json http://purl.obolibrary.org/obo/GO_0050742 GO:0050740 biolink:BiologicalProcess protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine. RESID:AA0349 go-plus.json http://purl.obolibrary.org/obo/GO_0050740 GO:0050745 biolink:BiologicalProcess peptide cross-linking via L-cysteinyl-5-imidazolinone glycine The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water. RESID:AA0188 go-plus.json http://purl.obolibrary.org/obo/GO_0050745 GO:0050746 biolink:BiologicalProcess regulation of lipoprotein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. go-plus.json regulation of lipoprotein metabolism http://purl.obolibrary.org/obo/GO_0050746 CHEBI:86490 biolink:ChemicalSubstance C4-acylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86490 chebi_ph7_3 GO:0050743 biolink:BiologicalProcess protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine The formation of a protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine. RESID:AA0352 go-plus.json http://purl.obolibrary.org/obo/GO_0050743 CHEBI:86492 biolink:ChemicalSubstance C5-acylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86492 chebi_ph7_3 GO:0050744 biolink:BiologicalProcess protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine The formation of a protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine. RESID:AA0353 go-plus.json http://purl.obolibrary.org/obo/GO_0050744 GO:0035190 biolink:BiologicalProcess syncytial nuclear migration The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0035190 CHEBI:86493 biolink:ChemicalSubstance C9-acylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86493 chebi_ph7_3 GO:0050749 biolink:MolecularActivity obsolete apolipoprotein E receptor binding OBSOLETE. Interacting selectively with an apolipoprotein E receptor. go-plus.json apolipoprotein E receptor binding http://purl.obolibrary.org/obo/GO_0050749 CHEBI:86494 biolink:ChemicalSubstance botanical anti-fungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_86494 GO:0050747 biolink:BiologicalProcess positive regulation of lipoprotein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. go-plus.json up regulation of lipoprotein metabolic process|activation of lipoprotein metabolic process|stimulation of lipoprotein metabolic process|up-regulation of lipoprotein metabolic process|positive regulation of lipoprotein metabolism|upregulation of lipoprotein metabolic process http://purl.obolibrary.org/obo/GO_0050747 GO:0050748 biolink:BiologicalProcess negative regulation of lipoprotein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. go-plus.json down regulation of lipoprotein metabolic process|downregulation of lipoprotein metabolic process|down-regulation of lipoprotein metabolic process|inhibition of lipoprotein metabolic process|negative regulation of lipoprotein metabolism http://purl.obolibrary.org/obo/GO_0050748 CHEBI:86496 biolink:ChemicalSubstance acetyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86496 CHEBI:86497 biolink:ChemicalSubstance hydroxykynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86497 CHEBI:86498 biolink:ChemicalSubstance hydroxylysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86498 CHEBI:86499 biolink:ChemicalSubstance monohydroxyproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_86499 GO:0035188 biolink:BiologicalProcess hatching The emergence of an immature organism from a protective structure. go-plus.json http://purl.obolibrary.org/obo/GO_0035188 GO:0035189 biolink:CellularComponent Rb-E2F complex A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression. go-plus.json retinoblastoma-E2F complex http://purl.obolibrary.org/obo/GO_0035189 GO:0035180 biolink:BiologicalProcess larval wandering behavior The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction. go-plus.json larval wandering behaviour http://purl.obolibrary.org/obo/GO_0035180 GO:0035181 biolink:BiologicalProcess larval burrowing behavior Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation. go-plus.json larval burrowing behaviour http://purl.obolibrary.org/obo/GO_0035181 GO:0035182 biolink:CellularComponent female germline ring canal outer rim An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues. go-plus.json germline ring canal outer rim|ovarian ring canal outer rim|nurse cell ring canal outer rim http://purl.obolibrary.org/obo/GO_0035182 GO:0035183 biolink:CellularComponent female germline ring canal inner rim A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins. go-plus.json germline ring canal inner rim|ovarian ring canal inner rim|nurse cell ring canal inner rim http://purl.obolibrary.org/obo/GO_0035183 GO:0035184 biolink:MolecularActivity histone threonine kinase activity Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json histone-threonine kinase activity http://purl.obolibrary.org/obo/GO_0035184 GO:0035185 biolink:BiologicalProcess preblastoderm mitotic cell cycle The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0035185 GO:0035186 biolink:BiologicalProcess syncytial blastoderm mitotic cell cycle Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively. go-plus.json http://purl.obolibrary.org/obo/GO_0035186 GO:0035187 biolink:BiologicalProcess hatching behavior The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell. go-plus.json hatching behaviour http://purl.obolibrary.org/obo/GO_0035187 GO:0050752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050752 GO:0050753 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050753 GO:0050750 biolink:MolecularActivity low-density lipoprotein particle receptor binding Binding to a low-density lipoprotein receptor. go-plus.json low-density lipoprotein receptor binding|LDL receptor binding http://purl.obolibrary.org/obo/GO_0050750 GO:0050751 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050751 GO:0050756 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050756 GO:0050757 biolink:BiologicalProcess thymidylate synthase biosynthetic process The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. go-plus.json thymidylate synthase anabolism|thymidylate synthase biosynthesis|thymidylate synthase synthesis|thymidylate synthase formation http://purl.obolibrary.org/obo/GO_0050757 GO:0050754 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050754 GO:0050755 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050755 GO:0050758 biolink:BiologicalProcess regulation of thymidylate synthase biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase. go-plus.json regulation of thymidylate synthase anabolism|regulation of thymidylate synthase synthesis|regulation of thymidylate synthase formation|regulation of thymidylate synthase biosynthesis http://purl.obolibrary.org/obo/GO_0050758 GO:0050759 biolink:BiologicalProcess positive regulation of thymidylate synthase biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase. go-plus.json positive regulation of thymidylate synthase formation|upregulation of thymidylate synthase biosynthetic process|up regulation of thymidylate synthase biosynthetic process|activation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase biosynthesis|stimulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase anabolism|up-regulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase synthesis http://purl.obolibrary.org/obo/GO_0050759 GO:0035177 biolink:BiologicalProcess larval foraging behavior The movement of a larva through a feeding substrate whilst feeding on food. go-plus.json larval foraging behaviour http://purl.obolibrary.org/obo/GO_0035177 GO:0035178 biolink:BiologicalProcess turning behavior Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source. go-plus.json turning behaviour http://purl.obolibrary.org/obo/GO_0035178 GO:0035179 biolink:BiologicalProcess larval turning behavior Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source. go-plus.json larval turning behaviour http://purl.obolibrary.org/obo/GO_0035179 GO:0035170 biolink:BiologicalProcess lymph gland crystal cell differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. go-plus.json http://purl.obolibrary.org/obo/GO_0035170 GO:0035171 biolink:BiologicalProcess lamellocyte differentiation The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. go-plus.json lamellocyte cell differentiation http://purl.obolibrary.org/obo/GO_0035171 GO:0035172 biolink:BiologicalProcess hemocyte proliferation The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. go-plus.json arthropod blood cell proliferation http://purl.obolibrary.org/obo/GO_0035172 GO:0035173 biolink:MolecularActivity histone kinase activity Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0035173 GO:0035174 biolink:MolecularActivity histone serine kinase activity Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json histone-serine kinase activity http://purl.obolibrary.org/obo/GO_0035174 GO:0035175 biolink:MolecularActivity histone kinase activity (H3-S10 specific) Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3. go-plus.json histone kinase activity (H3-S3 specific)|histone serine kinase activity (H3-S10 specific)|histone-serine kinase activity (H3-S10 specific) http://purl.obolibrary.org/obo/GO_0035175 GO:0035176 biolink:BiologicalProcess social behavior Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group. Wikipedia:Social_behavior go-plus.json cooperative behavior|social behaviour http://purl.obolibrary.org/obo/GO_0035176 GO:0050763 biolink:BiologicalProcess depsipeptide biosynthetic process The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively. go-plus.json depsipeptide anabolism|depsipeptide synthesis|depsipeptide biosynthesis|depsipeptide formation http://purl.obolibrary.org/obo/GO_0050763 GO:0050764 biolink:BiologicalProcess regulation of phagocytosis Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material. go-plus.json http://purl.obolibrary.org/obo/GO_0050764 GO:0050761 biolink:BiologicalProcess depsipeptide metabolic process The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively. go-plus.json depsipeptide metabolism http://purl.obolibrary.org/obo/GO_0050761 goslim_pir GO:0050762 biolink:BiologicalProcess depsipeptide catabolic process The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively. go-plus.json depsipeptide degradation|depsipeptide breakdown|depsipeptide catabolism http://purl.obolibrary.org/obo/GO_0050762 GO:0050767 biolink:BiologicalProcess regulation of neurogenesis Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0050767 GO:0050768 biolink:BiologicalProcess negative regulation of neurogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. go-plus.json down-regulation of neurogenesis|downregulation of neurogenesis|down regulation of neurogenesis|inhibition of neurogenesis http://purl.obolibrary.org/obo/GO_0050768 GO:0050765 biolink:BiologicalProcess negative regulation of phagocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis. go-plus.json downregulation of phagocytosis|down regulation of phagocytosis|inhibition of phagocytosis|down-regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0050765 GO:0050766 biolink:BiologicalProcess positive regulation of phagocytosis Any process that activates or increases the frequency, rate or extent of phagocytosis. go-plus.json up regulation of phagocytosis|upregulation of phagocytosis|stimulation of phagocytosis|activation of phagocytosis|up-regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0050766 GO:0050769 biolink:BiologicalProcess positive regulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. go-plus.json stimulation of neurogenesis|up-regulation of neurogenesis|activation of neurogenesis|up regulation of neurogenesis|upregulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050769 GO:0035166 biolink:BiologicalProcess post-embryonic hemopoiesis The stages of blood cell formation that take place after completion of embryonic development. go-plus.json post-embryonic haemopoiesis http://purl.obolibrary.org/obo/GO_0035166 GO:0035167 biolink:BiologicalProcess larval lymph gland hemopoiesis The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. go-plus.json larval lymph gland haemopoiesis|larval lymph gland hematopoiesis|larval lymph gland haematopoiesis http://purl.obolibrary.org/obo/GO_0035167 GO:0035168 biolink:BiologicalProcess larval lymph gland hemocyte differentiation The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. go-plus.json larval lymph gland arthropod blood cell differentiation http://purl.obolibrary.org/obo/GO_0035168 CHEBI:154293 biolink:ChemicalSubstance alpha-D-GlcpNAc-(1->4)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_154293 chebi_ph7_3 GO:0035169 biolink:BiologicalProcess lymph gland plasmatocyte differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte. go-plus.json lymph gland plasmatocyte cell differentiation http://purl.obolibrary.org/obo/GO_0035169 GO:0035160 biolink:BiologicalProcess maintenance of epithelial integrity, open tracheal system Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process. go-plus.json maintenance of tracheal epithelial integrity http://purl.obolibrary.org/obo/GO_0035160 GO:0035161 biolink:BiologicalProcess imaginal disc lineage restriction Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0035161 GO:0035162 biolink:BiologicalProcess embryonic hemopoiesis The stages of blood cell formation that take place within the embryo. go-plus.json embryonic hematopoiesis|embryonic haematopoiesis|embryonic haemopoiesis http://purl.obolibrary.org/obo/GO_0035162 GO:0050760 biolink:BiologicalProcess negative regulation of thymidylate synthase biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase. go-plus.json negative regulation of thymidylate synthase anabolism|negative regulation of thymidylate synthase synthesis|inhibition of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase formation|down regulation of thymidylate synthase biosynthetic process|downregulation of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase biosynthesis|down-regulation of thymidylate synthase biosynthetic process http://purl.obolibrary.org/obo/GO_0050760 GO:0035163 biolink:BiologicalProcess embryonic hemocyte differentiation The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. go-plus.json embryonic arthropod blood cell differentiation|embryonic hemocyte cell differentiation http://purl.obolibrary.org/obo/GO_0035163 GO:0035164 biolink:BiologicalProcess embryonic plasmatocyte differentiation The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte. go-plus.json embryonic plasmatocyte cell differentiation http://purl.obolibrary.org/obo/GO_0035164 GO:0035165 biolink:BiologicalProcess embryonic crystal cell differentiation The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. go-plus.json http://purl.obolibrary.org/obo/GO_0035165 GO:0050774 biolink:BiologicalProcess negative regulation of dendrite morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis. go-plus.json down-regulation of dendrite morphogenesis|downregulation of dendrite morphogenesis|down regulation of dendrite morphogenesis|inhibition of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0050774 GO:0050775 biolink:BiologicalProcess positive regulation of dendrite morphogenesis Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis. go-plus.json up regulation of dendrite morphogenesis|upregulation of dendrite morphogenesis|stimulation of dendrite morphogenesis|up-regulation of dendrite morphogenesis|activation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0050775 GO:0050772 biolink:BiologicalProcess positive regulation of axonogenesis Any process that activates or increases the frequency, rate or extent of axonogenesis. go-plus.json upregulation of axonogenesis|stimulation of axonogenesis|up-regulation of axonogenesis|activation of axonogenesis|up regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0050772 GO:0050773 biolink:BiologicalProcess regulation of dendrite development Any process that modulates the frequency, rate or extent of dendrite development. go-plus.json http://purl.obolibrary.org/obo/GO_0050773 GO:0050778 biolink:BiologicalProcess positive regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. go-plus.json stimulation of immune response|up-regulation of immune response|upregulation of immune response|up regulation of immune response http://purl.obolibrary.org/obo/GO_0050778 GO:0050779 biolink:BiologicalProcess RNA destabilization Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes. go-plus.json http://purl.obolibrary.org/obo/GO_0050779 GO:0050776 biolink:BiologicalProcess regulation of immune response Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0050776 GO:0050777 biolink:BiologicalProcess negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. go-plus.json down-regulation of immune response|inhibition of immune response|down regulation of immune response|downregulation of immune response http://purl.obolibrary.org/obo/GO_0050777 GO:0035155 biolink:BiologicalProcess negative regulation of terminal cell fate specification, open tracheal system Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates. go-plus.json downregulation of terminal cell fate specification|down regulation of terminal cell fate specification|inhibition of terminal cell fate specification|negative regulation of terminal cell fate specification|down-regulation of terminal cell fate specification http://purl.obolibrary.org/obo/GO_0035155 GO:0035156 biolink:BiologicalProcess fusion cell fate specification The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0035156 GO:0035157 biolink:BiologicalProcess negative regulation of fusion cell fate specification Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates. go-plus.json downregulation of fusion cell fate specification|down regulation of fusion cell fate specification|inhibition of fusion cell fate specification|down-regulation of fusion cell fate specification http://purl.obolibrary.org/obo/GO_0035157 GO:0035158 biolink:BiologicalProcess regulation of tube diameter, open tracheal system Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size. go-plus.json regulation of tracheal tube diameter|tracheal tube expansion|tracheal tube dilation http://purl.obolibrary.org/obo/GO_0035158 GO:0035159 biolink:BiologicalProcess regulation of tube length, open tracheal system Ensuring that a tube in an open tracheal system is of the correct length. go-plus.json tracheal tube elongation|regulation of tracheal tube length http://purl.obolibrary.org/obo/GO_0035159 GO:0035150 biolink:BiologicalProcess regulation of tube size Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes. go-plus.json http://purl.obolibrary.org/obo/GO_0035150 GO:0050770 biolink:BiologicalProcess regulation of axonogenesis Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0050770 GO:0035151 biolink:BiologicalProcess regulation of tube size, open tracheal system Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape. go-plus.json regulation of tracheal tube size http://purl.obolibrary.org/obo/GO_0035151 GO:0050771 biolink:BiologicalProcess negative regulation of axonogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. go-plus.json down regulation of axonogenesis|inhibition of axonogenesis|down-regulation of axonogenesis|downregulation of axonogenesis http://purl.obolibrary.org/obo/GO_0050771 GO:0035152 biolink:BiologicalProcess regulation of tube architecture, open tracheal system Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network. go-plus.json regulation of tracheal tube architecture http://purl.obolibrary.org/obo/GO_0035152 GO:0035153 biolink:BiologicalProcess epithelial cell type specification, open tracheal system Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions. go-plus.json tracheal cell type specification|tracheal epithelial cell type specification http://purl.obolibrary.org/obo/GO_0035153 GO:0035154 biolink:BiologicalProcess terminal cell fate specification, open tracheal system The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange. go-plus.json terminal cell fate specification http://purl.obolibrary.org/obo/GO_0035154 UBERON:0000219 biolink:AnatomicalEntity vertebral foramen of atlas . go-plus.json vertebral foramen of cervical vertebra 1 http://purl.obolibrary.org/obo/UBERON_0000219 GO:0001930 biolink:BiologicalProcess positive regulation of exocyst assembly Any process that increases the rate or extent of exocyst assembly. go-plus.json up regulation of exocyst assembly|upregulation of exocyst assembly|stimulation of exocyst assembly|activation of exocyst assembly|up-regulation of exocyst assembly http://purl.obolibrary.org/obo/GO_0001930 GO:0001931 biolink:CellularComponent uropod A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively. go-plus.json distal pole complex|retractile pole|uropodium http://purl.obolibrary.org/obo/GO_0001931 UBERON:0000218 biolink:AnatomicalEntity vertebral arch of axis A neural arch that is part of a vertebral bone 2. go-plus.json vertebral foramen of cervical vertebra 2 http://purl.obolibrary.org/obo/UBERON_0000218 CHEBI:37433 biolink:ChemicalSubstance gulonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37433 CHEBI:37434 biolink:ChemicalSubstance ribonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37434 CHEBI:62406 biolink:ChemicalSubstance 3-hydroxydecanoyl-3-hydroxydecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62406 CHEBI:62407 biolink:ChemicalSubstance UDP-N-acetyl-beta-L-fucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62407 GO:0001936 biolink:BiologicalProcess regulation of endothelial cell proliferation Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0001936 GO:0001937 biolink:BiologicalProcess negative regulation of endothelial cell proliferation Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. go-plus.json down-regulation of endothelial cell proliferation|downregulation of endothelial cell proliferation|down regulation of endothelial cell proliferation|inhibition of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001937 GO:0001938 biolink:BiologicalProcess positive regulation of endothelial cell proliferation Any process that activates or increases the rate or extent of endothelial cell proliferation. go-plus.json stimulation of endothelial cell proliferation|up-regulation of endothelial cell proliferation|activation of endothelial cell proliferation|up regulation of endothelial cell proliferation|upregulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001938 CHEBI:62408 biolink:ChemicalSubstance trans,trans-octa-2,4-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_62408 CHEBI:62409 biolink:ChemicalSubstance trans,trans-deca-2,4-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_62409 GO:0001939 biolink:CellularComponent female pronucleus The pronucleus originating from the ovum that is being fertilized. go-plus.json http://purl.obolibrary.org/obo/GO_0001939 GO:0001932 biolink:BiologicalProcess regulation of protein phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. go-plus.json regulation of protein amino acid phosphorylation http://purl.obolibrary.org/obo/GO_0001932 CHEBI:37431 biolink:ChemicalSubstance uronolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37431 GO:0001933 biolink:BiologicalProcess negative regulation of protein phosphorylation Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. go-plus.json down-regulation of protein amino acid phosphorylation|downregulation of protein amino acid phosphorylation|down regulation of protein amino acid phosphorylation|inhibition of protein amino acid phosphorylation|negative regulation of protein amino acid phosphorylation http://purl.obolibrary.org/obo/GO_0001933 CHEBI:37432 biolink:ChemicalSubstance mannonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37432 UBERON:0000220 biolink:AnatomicalEntity atlanto-occipital joint The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital go-plus.json occipito-atlantal joint|articulatio atlanto-occipitalis|craniovertebral joint|atlanto occipital joint|atlantooccipital joint|occipito atlantal joint|articulatio atlantooccipitalis http://purl.obolibrary.org/obo/UBERON_0000220 GO:0001934 biolink:BiologicalProcess positive regulation of protein phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. go-plus.json positive regulation of protein amino acid phosphorylation|stimulation of protein amino acid phosphorylation|up-regulation of protein amino acid phosphorylation|activation of protein amino acid phosphorylation|up regulation of protein amino acid phosphorylation|upregulation of protein amino acid phosphorylation http://purl.obolibrary.org/obo/GO_0001934 GO:0001935 biolink:BiologicalProcess endothelial cell proliferation The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0001935 UBERON:0000209 biolink:AnatomicalEntity tetrapod frontal bone the bone forming the forehead and roof of the eye orbit go-plus.json os frontale|os frontal|frontal|frontal bone http://purl.obolibrary.org/obo/UBERON_0000209 GO:0001940 biolink:CellularComponent male pronucleus The pronucleus originating from the spermatozoa that was involved in fertilization. go-plus.json http://purl.obolibrary.org/obo/GO_0001940 GO:0001941 biolink:BiologicalProcess postsynaptic membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). go-plus.json postsynaptic membrane organisation|post-synaptic membrane organization http://purl.obolibrary.org/obo/GO_0001941 GO:0001942 biolink:BiologicalProcess hair follicle development The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. go-plus.json http://purl.obolibrary.org/obo/GO_0001942 UBERON:0000204 biolink:AnatomicalEntity ventral part of telencephalon Ventral part (base region) of the telencephalon. go-plus.json area ventralis telencephali|subpallium|subpallium|ventral telencephalon http://purl.obolibrary.org/obo/UBERON_0000204 UBERON:0000207 biolink:AnatomicalEntity compound eye corneal lens A chitinous extracellular secretion of the four underlying cone cells and the pigment cells. go-plus.json acellular lens http://purl.obolibrary.org/obo/UBERON_0000207 UBERON:0014852 biolink:AnatomicalEntity chorda tendinea of right ventricle Chorda tendinea which is attached to the leaflet of tricuspid valve and is continuous with the endocardium of papillary muscle of right ventricle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014852 CHEBI:62410 biolink:ChemicalSubstance UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62410 UBERON:0014851 biolink:AnatomicalEntity chorda tendinea of left ventricle Chorda tendinea which is attached to the leaflet of mitral valve and is continuous with the endocardium of papillary muscle of left ventricle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014851 CHEBI:62413 biolink:ChemicalSubstance (S)-methylmalonate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_62413 chebi_ph7_3 CHEBI:62414 biolink:ChemicalSubstance biotinyl-5'-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62414 chebi_ph7_3 CHEBI:62411 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-beta-L-talose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62411 CHEBI:37445 biolink:ChemicalSubstance folic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_37445 CHEBI:62412 biolink:ChemicalSubstance phenazine-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62412 CHEBI:62417 biolink:ChemicalSubstance arabidiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62417 chebi_ph7_3 CHEBI:62418 biolink:ChemicalSubstance 3-oxohexanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62418 chebi_ph7_3 CHEBI:37448 biolink:ChemicalSubstance 2-dehydro-3-deoxy-L-fuconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37448 chebi_ph7_3 CHEBI:37449 biolink:ChemicalSubstance 2-deoxy-alpha-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_37449 chebi_ph7_3 CHEBI:62416 biolink:ChemicalSubstance dammarenediol-II go-plus.json http://purl.obolibrary.org/obo/CHEBI_62416 chebi_ph7_3 GO:0001947 biolink:BiologicalProcess heart looping The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation. go-plus.json cardiac looping http://purl.obolibrary.org/obo/GO_0001947 UBERON:0000211 biolink:AnatomicalEntity ligament Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ. go-plus.json ligament organ http://purl.obolibrary.org/obo/UBERON_0000211 GO:0001948 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001948 CHEBI:62419 biolink:ChemicalSubstance (1R,2S)-epoxypropylphosphonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62419 GO:0001949 biolink:BiologicalProcess sebaceous gland cell differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell. go-plus.json sebocytes differentiation http://purl.obolibrary.org/obo/GO_0001949 GO:0001943 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001943 GO:0001944 biolink:BiologicalProcess vasculature development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. go-plus.json vascular system development http://purl.obolibrary.org/obo/GO_0001944 GO:0001945 biolink:BiologicalProcess lymph vessel development The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0001945 CHEBI:37440 biolink:ChemicalSubstance 3-oxoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37440 UBERON:0000210 biolink:AnatomicalEntity tetrapod parietal bone In humans: bone forming side and roof of cranium. Each bone is irregularly quadrilateral in form, and has two surfaces, four borders, and four angles. go-plus.json parietal|parietal bone|os parietale|actinopterygian frontal bone|frontal bone http://purl.obolibrary.org/obo/UBERON_0000210 GO:0001946 biolink:BiologicalProcess lymphangiogenesis Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. Wikipedia:Lymphangiogenesis go-plus.json lymph vessel formation http://purl.obolibrary.org/obo/GO_0001946 NCBITaxon:35497 biolink:OrganismalEntity Suina go-plus.json Suiformes http://purl.obolibrary.org/obo/NCBITaxon_35497 NCBITaxon:35493 biolink:OrganismalEntity Streptophyta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_35493 CHEBI:62420 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62420 CHEBI:62421 biolink:ChemicalSubstance (S)-2-trans-abscisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62421 chebi_ph7_3 CHEBI:62424 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uloseuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62424 CHEBI:62423 biolink:ChemicalSubstance (2-hydroxyphenyl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62423 chebi_ph7_3 CHEBI:37412 biolink:ChemicalSubstance phosphoshikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37412 GO:0001918 biolink:MolecularActivity farnesylated protein binding Binding to a farnesylated protein. go-plus.json http://purl.obolibrary.org/obo/GO_0001918 CHEBI:62428 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-hex-4-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62428 CHEBI:62429 biolink:ChemicalSubstance 2-trans-abscisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62429 chebi_ph7_3 GO:0001919 biolink:BiologicalProcess regulation of receptor recycling Any process that modulates the frequency, rate, or extent of receptor recycling. go-plus.json http://purl.obolibrary.org/obo/GO_0001919 CHEBI:13488 biolink:ChemicalSubstance UDP-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_13488 CHEBI:62426 biolink:ChemicalSubstance 2-trans-abscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62426 CHEBI:37416 biolink:ChemicalSubstance EC 2.7.7.6 (RNA polymerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_37416 GO:0001914 biolink:BiologicalProcess regulation of T cell mediated cytotoxicity Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity. go-plus.json regulation of T lymphocyte mediated cytotoxicity|regulation of T-cell mediated cell death|regulation of T-cell mediated apoptosis|regulation of T cell mediated cell death|regulation of T cell mediated cytolysis|regulation of T-cell mediated cytotoxicity|regulation of T-cell mediated cell killing|regulation of T-lymphocyte mediated cytotoxicity|regulation of T cell mediated apoptosis|regulation of T-cell mediated cytolysis|regulation of T cell mediated cell killing http://purl.obolibrary.org/obo/GO_0001914 UBERON:0000200 biolink:AnatomicalEntity gyrus A ridge on the cerebral cortex. It is generally surrounded by one or more sulci . go-plus.json gyri|gyrus of cerebrum|gyrus of neuraxis|folium|folia|neuraxis gyrus|cerebral gyrus|folium of brain|gyrus of cerebral hemisphere|gyri of cerebrum http://purl.obolibrary.org/obo/UBERON_0000200 GO:0001915 biolink:BiologicalProcess negative regulation of T cell mediated cytotoxicity Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity. go-plus.json down regulation of T cell mediated cytotoxicity|inhibition of T cell mediated cytotoxicity|negative regulation of T cell mediated apoptosis|negative regulation of T cell mediated cell death|negative regulation of T-cell mediated cytotoxicity|negative regulation of T-cell mediated cytolysis|negative regulation of T-cell mediated cell killing|negative regulation of T-lymphocyte mediated cytotoxicity|negative regulation of T-cell mediated apoptosis|down-regulation of T cell mediated cytotoxicity|negative regulation of T cell mediated cell killing|negative regulation of T lymphocyte mediated cytotoxicity|negative regulation of T-cell mediated cell death|negative regulation of T cell mediated cytolysis|downregulation of T cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0001915 UBERON:0000201 biolink:AnatomicalEntity endothelial blood brain barrier A blood brain barrier that is composed of endothelial cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000201 GO:0001916 biolink:BiologicalProcess positive regulation of T cell mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity. go-plus.json upregulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated cytolysis|positive regulation of T cell mediated cell death|positive regulation of T-cell mediated cytotoxicity|stimulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated cell killing|positive regulation of T-cell mediated apoptosis|up-regulation of T cell mediated cytotoxicity|activation of T cell mediated cytotoxicity|positive regulation of T-lymphocyte mediated cytotoxicity|positive regulation of T cell mediated cytolysis|up regulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cell killing|positive regulation of T lymphocyte mediated cytotoxicity|positive regulation of T-cell mediated cell death|positive regulation of T cell mediated apoptosis http://purl.obolibrary.org/obo/GO_0001916 UBERON:0000203 biolink:AnatomicalEntity pallium Dorsal part (roof region) of the telencephalon[GO]. go-plus.json dorsal part of telencephalon|dorsal telencephalon|dorsal telencephalic area|area dorsalis telencephali http://purl.obolibrary.org/obo/UBERON_0000203 GO:0001917 biolink:CellularComponent photoreceptor inner segment The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. go-plus.json http://purl.obolibrary.org/obo/GO_0001917 goslim_pir GO:0001910 biolink:BiologicalProcess regulation of leukocyte mediated cytotoxicity Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity. go-plus.json regulation of leucocyte mediated cytotoxicity|regulation of immune cell mediated cell death|regulation of immune cell mediated cytotoxicity|regulation of immune cell mediated cell killing http://purl.obolibrary.org/obo/GO_0001910 GO:0001911 biolink:BiologicalProcess negative regulation of leukocyte mediated cytotoxicity Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. go-plus.json down regulation of leukocyte mediated cytotoxicity|downregulation of leukocyte mediated cytotoxicity|negative regulation of leucocyte mediated cytotoxicity|down-regulation of leukocyte mediated cytotoxicity|inhibition of leukocyte mediated cytotoxicity|negative regulation of immune cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0001911 GO:0001912 biolink:BiologicalProcess positive regulation of leukocyte mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity. go-plus.json upregulation of leukocyte mediated cytotoxicity|positive regulation of leucocyte mediated cytotoxicity|up regulation of leukocyte mediated cytotoxicity|activation of leukocyte mediated cytotoxicity|stimulation of leukocyte mediated cytotoxicity|positive regulation of immune cell mediated cytotoxicity|up-regulation of leukocyte mediated cytotoxicity http://purl.obolibrary.org/obo/GO_0001912 GO:0001913 biolink:BiologicalProcess T cell mediated cytotoxicity The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. go-plus.json T cell mediated cell death|T-cell mediated cytotoxicity|T cell mediated apoptosis|T-cell mediated cell killing|T-lymphocyte mediated cytotoxicity|T-cell mediated apoptosis|T cell mediated cell killing|T lymphocyte mediated cytotoxicity|T-cell mediated cell death|T cell mediated cytolysis http://purl.obolibrary.org/obo/GO_0001913 GO:0001920 biolink:BiologicalProcess negative regulation of receptor recycling Any process that stops, prevents, or reduces the rate of receptor recycling. go-plus.json downregulation of receptor recycling|down regulation of receptor recycling|inhibition of receptor recycling|down-regulation of receptor recycling http://purl.obolibrary.org/obo/GO_0001920 CHEBI:62431 biolink:ChemicalSubstance abscisic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_62431 CHEBI:62432 biolink:ChemicalSubstance abscisates go-plus.json http://purl.obolibrary.org/obo/CHEBI_62432 chebi_ph7_3 CHEBI:37424 biolink:ChemicalSubstance sterol 3-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_37424 chebi_ph7_3 CHEBI:62436 biolink:ChemicalSubstance (+)-abscisic acid D-glucopyranosyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_62436 chebi_ph7_3 CHEBI:37425 biolink:ChemicalSubstance L-galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37425 CHEBI:37422 biolink:ChemicalSubstance arabinono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37422 CHEBI:62433 biolink:ChemicalSubstance (R)-2-trans-abscisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62433 chebi_ph7_3 GO:0001929 biolink:BiologicalProcess negative regulation of exocyst assembly Any process that stops, prevents, or reduces the rate or extent of exocyst assembly. go-plus.json downregulation of exocyst assembly|down regulation of exocyst assembly|inhibition of exocyst assembly|down-regulation of exocyst assembly http://purl.obolibrary.org/obo/GO_0001929 CHEBI:62439 biolink:ChemicalSubstance soyasapogenol B 3-O-beta-glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62439 CHEBI:37429 biolink:ChemicalSubstance aldonolactone phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37429 CHEBI:37426 biolink:ChemicalSubstance aldarolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37426 CHEBI:62437 biolink:ChemicalSubstance (S)-2-trans-abscisic acid beta-D-glucopyranosyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_62437 chebi_ph7_3 CHEBI:37427 biolink:ChemicalSubstance ketoaldonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37427 CHEBI:62438 biolink:ChemicalSubstance (S)-2-trans-abscisic acid D-glucopyranosyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_62438 chebi_ph7_3 GO:0001925 biolink:BiologicalProcess negative regulation of B-1 B cell differentiation Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation. go-plus.json negative regulation of B-1 B-lymphocyte differentiation|negative regulation of B-1 B cell development|down-regulation of B-1 B cell differentiation|negative regulation of B-1 B lymphocyte differentiation|downregulation of B-1 B cell differentiation|down regulation of B-1 B cell differentiation|inhibition of B-1 B cell differentiation|negative regulation of B-1 B-cell differentiation http://purl.obolibrary.org/obo/GO_0001925 GO:0001926 biolink:BiologicalProcess positive regulation of B-1 B cell differentiation Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation. go-plus.json stimulation of B-1 B cell differentiation|positive regulation of B-1 B-cell differentiation|up-regulation of B-1 B cell differentiation|activation of B-1 B cell differentiation|positive regulation of B-1 B-lymphocyte differentiation|positive regulation of B-1 B cell development|up regulation of B-1 B cell differentiation|positive regulation of B-1 B lymphocyte differentiation|upregulation of B-1 B cell differentiation http://purl.obolibrary.org/obo/GO_0001926 GO:0001927 biolink:BiologicalProcess exocyst assembly The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex. go-plus.json http://purl.obolibrary.org/obo/GO_0001927 GO:0001928 biolink:BiologicalProcess regulation of exocyst assembly Any process that modulates the frequency, rate or extent of exocyst assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0001928 GO:0001921 biolink:BiologicalProcess positive regulation of receptor recycling Any process that activates or increases the frequency, rate or extent of receptor recycling. go-plus.json up regulation of receptor recycling|upregulation of receptor recycling|stimulation of receptor recycling|up-regulation of receptor recycling|activation of receptor recycling http://purl.obolibrary.org/obo/GO_0001921 CHEBI:37420 biolink:ChemicalSubstance 12-hydroxyjasmonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37420 GO:0001922 biolink:BiologicalProcess B-1 B cell homeostasis The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. go-plus.json B-1 B lymphocyte homeostasis|B-1 B-cell homeostasis|B-1 B-lymphocyte homeostasis http://purl.obolibrary.org/obo/GO_0001922 CHEBI:37421 biolink:ChemicalSubstance carbohydrate lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37421 GO:0001923 biolink:BiologicalProcess B-1 B cell differentiation The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. go-plus.json B-1 B cell development|B-1 B lymphocyte differentiation|B-1 B-cell differentiation|B-1 B-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0001923 GO:0001924 biolink:BiologicalProcess regulation of B-1 B cell differentiation Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. go-plus.json regulation of B-1 B-cell differentiation|regulation of B-1 B-lymphocyte differentiation|regulation of B-1 B cell development|regulation of B-1 B lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0001924 GO:0050900 biolink:BiologicalProcess leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body. go-plus.json leucocyte trafficking|leucocyte migration|leukocyte trafficking|immune cell trafficking|immune cell migration http://purl.obolibrary.org/obo/GO_0050900 GO:0050903 biolink:BiologicalProcess leukocyte activation-dependent arrest The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_0050903 GO:0050904 biolink:BiologicalProcess diapedesis The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. go-plus.json http://purl.obolibrary.org/obo/GO_0050904 GO:0050901 biolink:BiologicalProcess leukocyte tethering or rolling Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). go-plus.json http://purl.obolibrary.org/obo/GO_0050901 GO:0050902 biolink:BiologicalProcess leukocyte adhesive activation The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation. go-plus.json leukocyte adhesive triggering http://purl.obolibrary.org/obo/GO_0050902 CHEBI:62442 biolink:ChemicalSubstance soyasapogenol A 3-O-beta-glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62442 GO:0050907 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. go-plus.json sensory perception, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during sensory perception|sensory transduction of chemical stimulus|sensory detection of chemical stimulus during sensory perception|sensory detection of chemical stimulus|sensory perception, sensory detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0050907 CHEBI:62443 biolink:ChemicalSubstance soyasapogenol A 3-O-beta-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62443 chebi_ph7_3 GO:0050908 biolink:BiologicalProcess detection of light stimulus involved in visual perception The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. go-plus.json visual perception, sensory transduction of light stimulus|sensory detection of light during visual perception|sensory transduction of light stimulus during visual perception|visual perception, detection of light stimulus|sensory transduction of light during visual perception|sensory detection of light stimulus during visual perception|visual perception, sensory transduction during perception of light http://purl.obolibrary.org/obo/GO_0050908 CHEBI:62440 biolink:ChemicalSubstance soyasapogenol A go-plus.json http://purl.obolibrary.org/obo/CHEBI_62440 chebi_ph7_3 GO:0050905 biolink:BiologicalProcess neuromuscular process Any process pertaining to the functions of the nervous and muscular systems of an organism. go-plus.json neuromotor process|neuromuscular physiological process http://purl.obolibrary.org/obo/GO_0050905 CHEBI:62441 biolink:ChemicalSubstance soyasapogenol B 3-O-beta-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62441 chebi_ph7_3 GO:0050906 biolink:BiologicalProcess detection of stimulus involved in sensory perception The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. Wikipedia:Transduction_(physiology) go-plus.json sensory detection of stimulus|sensory transduction|sensory perception, sensory transduction of stimulus|sensory perception, stimulus detection http://purl.obolibrary.org/obo/GO_0050906 CHEBI:86412 biolink:ChemicalSubstance 3-oxochol-4-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86412 chebi_ph7_3 CHEBI:62446 biolink:ChemicalSubstance soyasapogenol E 3-O-beta-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62446 chebi_ph7_3 GO:2001196 biolink:BiologicalProcess positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine. go-plus.json positive regulation of lysine biosynthetic process via aminoadipic acid and saccharopine|positive regulation of lysine biosynthesis via aminoadipic acid and saccharopine http://purl.obolibrary.org/obo/GO_2001196 CHEBI:62447 biolink:ChemicalSubstance dammara-20,24-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62447 chebi_ph7_3 GO:2001197 biolink:BiologicalProcess basement membrane assembly involved in embryonic body morphogenesis Any basement membrane assembly that is involved in embryonic body morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_2001197 CHEBI:86414 biolink:ChemicalSubstance 3-oxocholesta-4,24-dien-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86414 chebi_ph7_3 CHEBI:62444 biolink:ChemicalSubstance soyasapogenol E go-plus.json http://purl.obolibrary.org/obo/CHEBI_62444 chebi_ph7_3 GO:2001198 biolink:BiologicalProcess regulation of dendritic cell differentiation Any process that modulates the frequency, rate or extent of dendritic cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001198 GO:2001199 biolink:BiologicalProcess negative regulation of dendritic cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001199 CHEBI:62445 biolink:ChemicalSubstance soyasapogenol E 3-O-beta-glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62445 CHEBI:62448 biolink:ChemicalSubstance indole-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62448 chebi_ph7_3 CHEBI:62449 biolink:ChemicalSubstance 4,4'-diapolycopene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62449 chebi_ph7_3 GO:2001190 biolink:BiologicalProcess positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. go-plus.json positive regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell http://purl.obolibrary.org/obo/GO_2001190 GO:2001191 biolink:BiologicalProcess regulation of gamma-delta T cell activation involved in immune response Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response. go-plus.json regulation of gamma-delta T lymphocyte activation during immune response|regulation of gamma-delta T-cell activation during immune response|regulation of gamma-delta T-lymphocyte activation during immune response|regulation of gamma-delta T cell activation during immune response http://purl.obolibrary.org/obo/GO_2001191 GO:2001192 biolink:BiologicalProcess negative regulation of gamma-delta T cell activation involved in immune response Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response. go-plus.json negative regulation of gamma-delta T-cell activation during immune response|negative regulation of gamma-delta T-lymphocyte activation during immune response|negative regulation of gamma-delta T cell activation during immune response|negative regulation of gamma-delta T lymphocyte activation during immune response http://purl.obolibrary.org/obo/GO_2001192 GO:2001193 biolink:BiologicalProcess positive regulation of gamma-delta T cell activation involved in immune response Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response. go-plus.json positive regulation of gamma-delta T-cell activation during immune response|positive regulation of gamma-delta T-lymphocyte activation during immune response|positive regulation of gamma-delta T cell activation during immune response|positive regulation of gamma-delta T lymphocyte activation during immune response http://purl.obolibrary.org/obo/GO_2001193 GO:2001194 biolink:BiologicalProcess regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine. go-plus.json regulation of lysine biosynthesis via aminoadipic acid and saccharopine|regulation of lysine biosynthetic process via aminoadipic acid and saccharopine http://purl.obolibrary.org/obo/GO_2001194 GO:2001195 biolink:BiologicalProcess negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine. go-plus.json negative regulation of lysine biosynthesis via aminoadipic acid and saccharopine|negative regulation of lysine biosynthetic process via aminoadipic acid and saccharopine http://purl.obolibrary.org/obo/GO_2001195 UBERON:0014891 biolink:AnatomicalEntity brainstem white matter White matter that is part of a brainstem [Automatically generated definition]. go-plus.json brainstem tracts|brainstem tracts and commissures|brainstem tract/commissure|brain stem white matter http://purl.obolibrary.org/obo/UBERON_0014891 GO:0050910 biolink:BiologicalProcess detection of mechanical stimulus involved in sensory perception of sound The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. go-plus.json perception of sound, sensory detection of mechanical stimulus|perception of sound, detection of mechanical stimulus|perception of sound, sensory transduction of mechanical stimulus|sensory transduction of sound|sensory detection of mechanical stimulus during perception of sound|detection of sound|hearing, sensory transduction of sound|sensory transduction of mechanical stimulus during perception of sound http://purl.obolibrary.org/obo/GO_0050910 GO:0050911 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of smell The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal. go-plus.json sensory transduction of scent|perception of smell, sensory transduction of chemical stimulus|sensory detection of scent|perception of smell, sensory detection of chemical stimulus|perception of smell, detection of chemical stimulus|sensory detection of chemical stimulus during perception of smell|sensory transduction of smell|sensory transduction of chemical stimulus during perception of smell|sensory detection of smell http://purl.obolibrary.org/obo/GO_0050911 GO:0050914 biolink:BiologicalProcess sensory perception of salty taste The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json salty taste perception http://purl.obolibrary.org/obo/GO_0050914 UBERON:0014896 biolink:AnatomicalEntity transversely striated somatic muscle A somatic muscle that consists of one or more somatic muscle myotubes and any associated extracellular structures. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014896 GO:0050915 biolink:BiologicalProcess sensory perception of sour taste The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json sour taste perception http://purl.obolibrary.org/obo/GO_0050915 CHEBI:62450 biolink:ChemicalSubstance 4,4'-diapolycopenedial go-plus.json http://purl.obolibrary.org/obo/CHEBI_62450 chebi_ph7_3 GO:0050912 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of taste The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. go-plus.json sensory transduction of taste|sensory detection of chemical stimulus during perception of taste|sensory detection of taste|sensory transduction of chemical stimulus during perception of taste|taste perception|perception of taste, sensory transduction of chemical stimulus|perception of taste, sensory detection of chemical stimulus|perception of taste, detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0050912 GO:0050913 biolink:BiologicalProcess sensory perception of bitter taste The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json bitter taste perception http://purl.obolibrary.org/obo/GO_0050913 CHEBI:37409 biolink:ChemicalSubstance crown compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37409 GO:0050918 biolink:BiologicalProcess positive chemotaxis The directed movement of a motile cell or organism towards a higher concentration of a chemical. go-plus.json chemoattraction http://purl.obolibrary.org/obo/GO_0050918 UBERON:0014892 biolink:AnatomicalEntity skeletal muscle organ A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). go-plus.json skeletal muscle http://purl.obolibrary.org/obo/UBERON_0014892 GO:0050919 biolink:BiologicalProcess negative chemotaxis The directed movement of a motile cell or organism towards a lower concentration of a chemical. go-plus.json chemoaversion|chemorepulsion http://purl.obolibrary.org/obo/GO_0050919 GO:0050916 biolink:BiologicalProcess sensory perception of sweet taste The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json sweet taste perception http://purl.obolibrary.org/obo/GO_0050916 CHEBI:86400 biolink:ChemicalSubstance levodione go-plus.json http://purl.obolibrary.org/obo/CHEBI_86400 chebi_ph7_3 PR:000009001 biolink:Protein interleukin-23 receptor A protein that is a translation product of the human IL23R gene or a 1:1 ortholog thereof. go-plus.json IL-23 receptor|IL23R|IL-23R http://purl.obolibrary.org/obo/PR_000009001 GO:0050917 biolink:BiologicalProcess sensory perception of umami taste The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process. go-plus.json umami taste perception http://purl.obolibrary.org/obo/GO_0050917 CHEBI:86401 biolink:ChemicalSubstance N-Acetyldemethylphosphinothricinate (2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86401 chebi_ph7_3 UBERON:0014895 biolink:AnatomicalEntity somatic muscle A muscle structure of invertebrates whose origin and insertion sites are in basal side of the epidermis or structures derived from it. The simplest somatic muscles consist of a single cell and associated extracellular structures. go-plus.json skeletal muscle http://purl.obolibrary.org/obo/UBERON_0014895 CHEBI:62452 biolink:ChemicalSubstance camelliol C go-plus.json http://purl.obolibrary.org/obo/CHEBI_62452 chebi_ph7_3 CHEBI:62457 biolink:ChemicalSubstance (17Z)-protosta-17(20),24-dien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62457 chebi_ph7_3 CHEBI:62458 biolink:ChemicalSubstance sophoradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62458 chebi_ph7_3 GO:0050909 biolink:BiologicalProcess sensory perception of taste The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. Wikipedia:Taste go-plus.json gustation|sense of taste|taste|taste perception http://purl.obolibrary.org/obo/GO_0050909 CHEBI:62455 biolink:ChemicalSubstance germanicol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62455 chebi_ph7_3 CHEBI:62456 biolink:ChemicalSubstance cucurbitadienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62456 chebi_ph7_3 GO:0001907 biolink:BiologicalProcess killing by symbiont of host cells Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json pathogenesis http://purl.obolibrary.org/obo/GO_0001907 CHEBI:37407 biolink:ChemicalSubstance cyclic ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_37407 GO:0001908 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001908 GO:0001909 biolink:BiologicalProcess leukocyte mediated cytotoxicity The directed killing of a target cell by a leukocyte. go-plus.json leucocyte mediated cytotoxicity|immune cell mediated cell death|immune cell mediated cytotoxicity|immune cell mediated cell killing http://purl.obolibrary.org/obo/GO_0001909 CHEBI:62459 biolink:ChemicalSubstance 24-hydroxy-beta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62459 chebi_ph7_3 CHEBI:37404 biolink:ChemicalSubstance elemental copper go-plus.json http://purl.obolibrary.org/obo/CHEBI_37404 GO:0001903 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001903 GO:0001904 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001904 GO:0001905 biolink:BiologicalProcess activation of membrane attack complex The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis. go-plus.json activation of TCC|membrane attack complex assembly|MAC formation|activation of the terminal complement cascade|MAC assembly|activation of terminal complement complex|activation of MAC|membrane attack complex formation http://purl.obolibrary.org/obo/GO_0001905 GO:0001906 biolink:BiologicalProcess cell killing Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. go-plus.json necrosis http://purl.obolibrary.org/obo/GO_0001906 goslim_pir GO:0001900 biolink:BiologicalProcess positive regulation of cytolysis by symbiont of host cells Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json upregulation by symbiont of cytolysis of host cells|positive regulation by symbiont of cytolysis of host cells|up regulation by symbiont of cytolysis of host cells|activation by symbiont of cytolysis of host cells|stimulation by symbiont of cytolysis of host cells|up-regulation by symbiont of cytolysis of host cells http://purl.obolibrary.org/obo/GO_0001900 GO:0001901 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001901 GO:0001902 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001902 GO:0050921 biolink:BiologicalProcess positive regulation of chemotaxis Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. go-plus.json upregulation of chemotaxis|stimulation of chemotaxis|up-regulation of chemotaxis|activation of chemotaxis|up regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0050921 GO:0050922 biolink:BiologicalProcess negative regulation of chemotaxis Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. go-plus.json down regulation of chemotaxis|inhibition of chemotaxis|down-regulation of chemotaxis|downregulation of chemotaxis http://purl.obolibrary.org/obo/GO_0050922 GO:0050920 biolink:BiologicalProcess regulation of chemotaxis Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0050920 GO:0050925 biolink:BiologicalProcess negative regulation of negative chemotaxis Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. go-plus.json down-regulation of negative chemotaxis|inhibition of negative chemotaxis|down regulation of negative chemotaxis|downregulation of negative chemotaxis http://purl.obolibrary.org/obo/GO_0050925 CHEBI:62460 biolink:ChemicalSubstance helvolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62460 GO:0050926 biolink:BiologicalProcess regulation of positive chemotaxis Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. go-plus.json http://purl.obolibrary.org/obo/GO_0050926 UBERON:0014886 biolink:AnatomicalEntity distal epiphysis of distal phalanx of manual digit go-plus.json head of distal phalanx of digit of manus|distal end of distal phalanx of finger|head of distal phalanx of digit of hand|head of distal phalanx of finger http://purl.obolibrary.org/obo/UBERON_0014886 CHEBI:62461 biolink:ChemicalSubstance helvolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62461 chebi_ph7_3 UBERON:0014887 biolink:AnatomicalEntity distal epiphysis of distal phalanx of digit A distal epiphysis that is part of a distal phalanx. go-plus.json head of distal phalanx of digit of autopod|head of distal phalanx|head of distal phalanx of digit|distal end of distal phalanx of digit http://purl.obolibrary.org/obo/UBERON_0014887 GO:0050923 biolink:BiologicalProcess regulation of negative chemotaxis Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. go-plus.json http://purl.obolibrary.org/obo/GO_0050923 GO:0050924 biolink:BiologicalProcess positive regulation of negative chemotaxis Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. go-plus.json activation of negative chemotaxis|stimulation of negative chemotaxis|up-regulation of negative chemotaxis|upregulation of negative chemotaxis|up regulation of negative chemotaxis http://purl.obolibrary.org/obo/GO_0050924 GO:0050929 biolink:BiologicalProcess induction of negative chemotaxis Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. go-plus.json http://purl.obolibrary.org/obo/GO_0050929 CHEBI:62464 biolink:ChemicalSubstance O-(3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosaminyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62464 CHEBI:62465 biolink:ChemicalSubstance O-(3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosaminyl)-L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62465 chebi_ph7_3 GO:0050927 biolink:BiologicalProcess positive regulation of positive chemotaxis Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. go-plus.json up regulation of positive chemotaxis|activation of positive chemotaxis|stimulation of positive chemotaxis|up-regulation of positive chemotaxis|upregulation of positive chemotaxis http://purl.obolibrary.org/obo/GO_0050927 CHEBI:86433 biolink:ChemicalSubstance 4-hydroxybenzoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_86433 CHEBI:62462 biolink:ChemicalSubstance isoguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62462 chebi_ph7_3 CHEBI:86434 biolink:ChemicalSubstance (25R)-3beta,4beta-dihydroxycholest-5-en-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86434 GO:0050928 biolink:BiologicalProcess negative regulation of positive chemotaxis Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. go-plus.json downregulation of positive chemotaxis|down-regulation of positive chemotaxis|inhibition of positive chemotaxis|down regulation of positive chemotaxis http://purl.obolibrary.org/obo/GO_0050928 CHEBI:62463 biolink:ChemicalSubstance 7,9,9'-tri-cis-neurosporene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62463 chebi_ph7_3 CHEBI:86435 biolink:ChemicalSubstance 4-hydroxybenzoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86435 chebi_ph7_3 CHEBI:62466 biolink:ChemicalSubstance 7,7',9,9'-tetra-cis-lycopene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62466 chebi_ph7_3 GO:0050932 biolink:BiologicalProcess regulation of pigment cell differentiation Any process that modulates the frequency, rate or extent of pigmented cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0050932 GO:0050933 biolink:BiologicalProcess early stripe melanocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development). go-plus.json early stripe melanophore differentiation|early stripe melanocyte cell differentiation http://purl.obolibrary.org/obo/GO_0050933 GO:0050930 biolink:BiologicalProcess induction of positive chemotaxis Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. go-plus.json http://purl.obolibrary.org/obo/GO_0050930 GO:0050931 biolink:BiologicalProcess pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. go-plus.json chromatophore differentiation|pigmented cell differentiation http://purl.obolibrary.org/obo/GO_0050931 NCBITaxon:359160 biolink:OrganismalEntity BOP clade go-plus.json BEP clade http://purl.obolibrary.org/obo/NCBITaxon_359160 GO:0050936 biolink:BiologicalProcess xanthophore differentiation The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance. go-plus.json xanthophore cell differentiation http://purl.obolibrary.org/obo/GO_0050936 GO:0050937 biolink:BiologicalProcess regulation of iridophore differentiation Any process that modulates the frequency, rate or extent of iridophore differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0050937 GO:0050934 biolink:BiologicalProcess late stripe melanocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development). go-plus.json late stripe melanophore differentiation|late stripe melanocyte cell differentiation http://purl.obolibrary.org/obo/GO_0050934 UBERON:0014876 biolink:AnatomicalEntity distal epiphysis of distal phalanx of pedal digit go-plus.json head of distal phalanx of toe|head of distal phalanx of digit of foot|distal end of distal phalanx of toe|head of distal phalanx of digit of pes http://purl.obolibrary.org/obo/UBERON_0014876 GO:0050935 biolink:BiologicalProcess iridophore differentiation The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance. go-plus.json iridophore cell differentiation http://purl.obolibrary.org/obo/GO_0050935 CHEBI:86420 biolink:ChemicalSubstance imidazole antifungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_86420 CHEBI:62476 biolink:ChemicalSubstance 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62476 CHEBI:86421 biolink:ChemicalSubstance 2-nitrophenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_86421 GO:0050938 biolink:BiologicalProcess regulation of xanthophore differentiation Any process that modulates the frequency, rate or extent of xanthophore differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0050938 GO:0050939 biolink:BiologicalProcess regulation of early stripe melanocyte differentiation Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation. go-plus.json regulation of early stripe melanophore differentiation http://purl.obolibrary.org/obo/GO_0050939 CHEBI:62474 biolink:ChemicalSubstance all-trans-3,4-didehydrolycopene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62474 chebi_ph7_3 CHEBI:86426 biolink:ChemicalSubstance triazole antifungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_86426 CHEBI:62478 biolink:ChemicalSubstance 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62478 chebi_ph7_3 GO:0035306 biolink:BiologicalProcess positive regulation of dephosphorylation Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule. go-plus.json up-regulation of dephosphorylation|upregulation of dephosphorylation|up regulation of dephosphorylation|activation of dephosphorylation|stimulation of dephosphorylation http://purl.obolibrary.org/obo/GO_0035306 GO:0035307 biolink:BiologicalProcess positive regulation of protein dephosphorylation Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein. go-plus.json activation of protein amino acid dephosphorylation|up regulation of protein amino acid dephosphorylation|upregulation of protein amino acid dephosphorylation|positive regulation of protein amino acid dephosphorylation|stimulation of protein amino acid dephosphorylation|up-regulation of protein amino acid dephosphorylation http://purl.obolibrary.org/obo/GO_0035307 GO:0035308 biolink:BiologicalProcess negative regulation of protein dephosphorylation Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein. go-plus.json down-regulation of protein amino acid dephosphorylation|downregulation of protein amino acid dephosphorylation|down regulation of protein amino acid dephosphorylation|inhibition of protein amino acid dephosphorylation|negative regulation of protein amino acid dephosphorylation http://purl.obolibrary.org/obo/GO_0035308 GO:0035309 biolink:BiologicalProcess wing and notum subfield formation The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures. go-plus.json http://purl.obolibrary.org/obo/GO_0035309 GO:0035300 biolink:MolecularActivity obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate. go-plus.json IP56K|inositol trisphosphate 5/6-kinase activity|Ins(1,3,4)P3 5/6-kinase activity|inositol 1,3,4-trisphosphate 6-kinase activity|inositol 1,3,4-trisphosphate 5-kinase activity|ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase activity|inositol-1,3,4-trisphosphate 5/6-kinase activity http://purl.obolibrary.org/obo/GO_0035300 GO:0035301 biolink:CellularComponent Hedgehog signaling complex A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila). go-plus.json HSC|Hedgehog signalling complex http://purl.obolibrary.org/obo/GO_0035301 GO:0035302 biolink:MolecularActivity ecdysteroid 25-hydroxylase activity Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods. go-plus.json http://purl.obolibrary.org/obo/GO_0035302 GO:0035303 biolink:BiologicalProcess regulation of dephosphorylation Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035303 GO:0035304 biolink:BiologicalProcess regulation of protein dephosphorylation Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein. go-plus.json regulation of protein amino acid dephosphorylation http://purl.obolibrary.org/obo/GO_0035304 GO:0035305 biolink:BiologicalProcess negative regulation of dephosphorylation Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule. go-plus.json inhibition of dephosphorylation|down regulation of dephosphorylation|downregulation of dephosphorylation|down-regulation of dephosphorylation http://purl.obolibrary.org/obo/GO_0035305 CHEBI:144503 biolink:ChemicalSubstance 5-deoxy-alpha-D-ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_144503 chebi_ph7_3 NCBITaxon:1897064 biolink:OrganismalEntity Cryptococcus neoformans species complex go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1897064 GO:0001994 biolink:BiologicalProcess norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure. go-plus.json norepinephrine-epinephrine vasoconstriction during control of blood pressure|noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure|norepinephrine-epinephrine vasoconstriction during blood pressure regulation|norepinephrine-epinephrine vasoconstriction during blood pressure control http://purl.obolibrary.org/obo/GO_0001994 GO:0001995 biolink:BiologicalProcess norepinephrine-epinephrine catabolic process in blood stream The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream. go-plus.json noradrenaline-adrenalin catabolic process in blood stream http://purl.obolibrary.org/obo/GO_0001995 GO:0001996 biolink:BiologicalProcess positive regulation of heart rate by epinephrine-norepinephrine The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction. go-plus.json positive regulation of heart contraction rate by adrenaline-noradrenaline|positive control of heart contraction rate by epinephrine-norepinephrine|up regulation of heart contraction rate by epinephrine-norepinephrine|positive regulation of heart contraction rate by epinephrine-norepinephrine|increased chronotropy by epinephrine-norepinephrine|upregulation of heart contraction rate by epinephrine-norepinephrine|stimulation of heart contraction rate by epinephrine-norepinephrine|positive regulation of cardiac contraction rate by epinephrine-norepinephrine|up-regulation of heart contraction rate by epinephrine-norepinephrine|activation of heart contraction rate by epinephrine-norepinephrine http://purl.obolibrary.org/obo/GO_0001996 GO:0001997 biolink:BiologicalProcess positive regulation of the force of heart contraction by epinephrine-norepinephrine Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings. go-plus.json positive regulation of heart contraction by adrenaline-noradrenaline|positive regulation of heart contraction by epinephrine-norepinephrine|increased inotropy by epinephrine-norepinephrine|increased strength of cardiac contraction by epinephrine-norepinephrine|increased force of heart contraction by adrenaline-noradrenaline|increased force of heart contraction by epinephrine-norepinephrine http://purl.obolibrary.org/obo/GO_0001997 GO:0001990 biolink:BiologicalProcess regulation of systemic arterial blood pressure by hormone The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. go-plus.json blood pressure regulation by hormone|hormonal control of blood pressure|hormonal regulation of blood pressure http://purl.obolibrary.org/obo/GO_0001990 GO:0001991 biolink:BiologicalProcess regulation of systemic arterial blood pressure by circulatory renin-angiotensin The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen. go-plus.json control of blood pressure by circulatory renin-angiotensin|circulatory renin-angiotensin blood pressure regulation|circulatory renin-angiotensin regulation of blood pressure|renin-angiotensin blood pressure control|circulatory renin-angiotensin control of blood pressure http://purl.obolibrary.org/obo/GO_0001991 GO:0001992 biolink:BiologicalProcess regulation of systemic arterial blood pressure by vasopressin The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. go-plus.json blood pressure regulation by vasopressin|vasopressin control of blood pressure http://purl.obolibrary.org/obo/GO_0001992 GO:0001993 biolink:BiologicalProcess regulation of systemic arterial blood pressure by norepinephrine-epinephrine The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system. go-plus.json noradrenaline-adrenaline regulation of blood pressure|norepinephrine-epinephrine blood pressure regulation|norepinephrine-epinephrine blood pressure control http://purl.obolibrary.org/obo/GO_0001993 CHEBI:37493 biolink:ChemicalSubstance 1D-myo-inositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37493 GO:0001998 biolink:BiologicalProcess angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream. go-plus.json angiotensin mediated vasoconstriction during control of blood pressure|angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure|angiotensin mediated vasoconstriction during blood pressure control|angiotensin mediated vasoconstriction during blood pressure regulation http://purl.obolibrary.org/obo/GO_0001998 GO:0001999 biolink:BiologicalProcess renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure The physiological response of the kidneys to a decrease in blood flow. go-plus.json renal response to blood flow during renin-angiotensin control of blood pressure http://purl.obolibrary.org/obo/GO_0001999 CHEBI:37496 biolink:ChemicalSubstance tetrahydroxyanthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37496 GO:0001972 biolink:MolecularActivity retinoic acid binding Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0001972 GO:0001973 biolink:BiologicalProcess G protein-coupled adenosine receptor signaling pathway The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. go-plus.json adenosine receptor signaling pathway|P1 receptor signaling pathway|adenosine receptor signaling pathway, G-protein coupled|adenosine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0001973 NCBITaxon:2290931 biolink:OrganismalEntity Stenosarchaea group go-plus.json Stenosarchaea http://purl.obolibrary.org/obo/NCBITaxon_2290931 GO:0001974 biolink:BiologicalProcess blood vessel remodeling The reorganization or renovation of existing blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0001974 GO:0001975 biolink:BiologicalProcess response to amphetamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_0001975 GO:0001970 biolink:BiologicalProcess positive regulation of activation of membrane attack complex Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. go-plus.json positive regulation of MAC assembly|stimulation of activation of membrane attack complex|up-regulation of activation of membrane attack complex|positive regulation of MAC formation|positive regulation of activation of TCC|upregulation of activation of membrane attack complex|positive regulation of activation of the terminal complement cascade|positive regulation of activation of terminal complement complex|positive regulation of membrane attack complex formation|positive regulation of membrane attack complex assembly|positive regulation of activation of MAC|up regulation of activation of membrane attack complex|activation of activation of membrane attack complex http://purl.obolibrary.org/obo/GO_0001970 GO:0001971 biolink:BiologicalProcess negative regulation of activation of membrane attack complex Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. go-plus.json down-regulation of activation of membrane attack complex|inhibition of activation of membrane attack complex|negative regulation of MAC formation|negative regulation of activation of TCC|negative regulation of membrane attack complex assembly|negative regulation of activation of the terminal complement cascade|down regulation of activation of membrane attack complex|negative regulation of activation of terminal complement complex|downregulation of activation of membrane attack complex|negative regulation of membrane attack complex formation|negative regulation of activation of MAC|negative regulation of MAC assembly http://purl.obolibrary.org/obo/GO_0001971 CHEBI:37470 biolink:ChemicalSubstance trans-9,10-dihydrophenanthrene-9,10-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37470 GO:0001976 biolink:BiologicalProcess nervous system process involved in regulation of systemic arterial blood pressure The regulation of blood pressure mediated by detection of stimuli and a neurological response. go-plus.json blood pressure regulation by neurological process|fast control of arterial pressure|neurological system process involved in regulation of systemic arterial blood pressure|neurological process involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0001976 GO:0001977 biolink:BiologicalProcess renal system process involved in regulation of blood volume A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. go-plus.json renal blood volume control of blood pressure|renal regulation of blood volume http://purl.obolibrary.org/obo/GO_0001977 GO:0001978 biolink:BiologicalProcess regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control. go-plus.json baroreceptor pressure buffer system|baroreceptor feedback control of blood pressure|carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0001978 GO:0001979 biolink:BiologicalProcess regulation of systemic arterial blood pressure by chemoreceptor signaling The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. go-plus.json chemoreceptor control of blood pressure|regulation of systemic arterial blood pressure by chemoreceptor signalling|chemoreceptor regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0001979 GO:0001983 biolink:BiologicalProcess baroreceptor response to increased systemic arterial blood pressure The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0001983 GO:0001984 biolink:BiologicalProcess artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure. go-plus.json vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0001984 GO:0001985 biolink:BiologicalProcess negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure. go-plus.json down-regulation of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of heart contraction rate in baroreceptor response to increased blood pressure|inhibition of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of cardiac contraction rate in baroreceptor response to increased blood pressure|down regulation of heart contraction rate in baroreceptor response to increased blood pressure|downregulation of heart contraction rate in baroreceptor response to increased blood pressure|negative control of heart contraction rate in baroreceptor response to increased blood pressure http://purl.obolibrary.org/obo/GO_0001985 GO:0001986 biolink:BiologicalProcess negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure. go-plus.json decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure|decreased strength of cardiac contraction during baroreceptor response to increased blood pressure http://purl.obolibrary.org/obo/GO_0001986 GO:0001980 biolink:BiologicalProcess regulation of systemic arterial blood pressure by ischemic conditions The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system. go-plus.json CNS ischemic response|ischemic control of blood pressure|ischemic regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0001980 GO:0001981 biolink:BiologicalProcess baroreceptor detection of arterial stretch The series of events by which the change in diameter of an artery is detected and converted to a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0001981 GO:0001982 biolink:BiologicalProcess baroreceptor response to decreased systemic arterial blood pressure The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0001982 CHEBI:37488 biolink:ChemicalSubstance trihydroxyanthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37488 CHEBI:13497 biolink:ChemicalSubstance UDP-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_13497 CHEBI:37483 biolink:ChemicalSubstance monohydroxyanthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37483 CHEBI:37480 biolink:ChemicalSubstance D-galactopyranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37480 CHEBI:37481 biolink:ChemicalSubstance amidoalkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37481 GO:0001987 biolink:BiologicalProcess vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure. go-plus.json http://purl.obolibrary.org/obo/GO_0001987 GO:0001988 biolink:BiologicalProcess positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure. go-plus.json up regulation of heart contraction rate in baroreceptor response to decreased blood pressure|activation of heart contraction rate in baroreceptor response to decreased blood pressure|stimulation of heart contraction rate in baroreceptor response to decreased blood pressure|positive control of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure|up-regulation of heart contraction rate in baroreceptor response to decreased blood pressure|upregulation of heart contraction rate in baroreceptor response to decreased blood pressure http://purl.obolibrary.org/obo/GO_0001988 GO:0001989 biolink:BiologicalProcess positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure. go-plus.json increased force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|positive regulation of the force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|increased strength of cardiac contraction during baroreceptor response to decreased blood pressure http://purl.obolibrary.org/obo/GO_0001989 CHEBI:37484 biolink:ChemicalSubstance dihydroxyanthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37484 CHEBI:37485 biolink:ChemicalSubstance hydroxyanthraquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_37485 GO:0001950 biolink:CellularComponent obsolete plasma membrane enriched fraction OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes. go-plus.json PME fraction|plasma membrane enriched fraction http://purl.obolibrary.org/obo/GO_0001950 GO:0001951 biolink:BiologicalProcess intestinal D-glucose absorption Uptake of D-glucose into the blood by absorption from the small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0001951 GO:0001952 biolink:BiologicalProcess regulation of cell-matrix adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0001952 GO:0001953 biolink:BiologicalProcess negative regulation of cell-matrix adhesion Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix. go-plus.json down-regulation of cell-matrix adhesion|downregulation of cell-matrix adhesion|down regulation of cell-matrix adhesion|inhibition of cell-matrix adhesion http://purl.obolibrary.org/obo/GO_0001953 CHEBI:37455 biolink:ChemicalSubstance ribulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37455 GO:0001958 biolink:BiologicalProcess endochondral ossification Replacement ossification wherein bone tissue replaces cartilage. Wikipedia:Endochondral_ossification go-plus.json http://purl.obolibrary.org/obo/GO_0001958 GO:0001959 biolink:BiologicalProcess regulation of cytokine-mediated signaling pathway Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway. go-plus.json regulation of cytokine mediated signalling pathway|regulation of cytokine and chemokine mediated signaling pathway|regulation of cytokine mediated signaling pathway http://purl.obolibrary.org/obo/GO_0001959 CHEBI:37450 biolink:ChemicalSubstance 2-methoxyestrone 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_37450 GO:0001954 biolink:BiologicalProcess positive regulation of cell-matrix adhesion Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix. go-plus.json up-regulation of cell-matrix adhesion|activation of cell-matrix adhesion|up regulation of cell-matrix adhesion|upregulation of cell-matrix adhesion|stimulation of cell-matrix adhesion http://purl.obolibrary.org/obo/GO_0001954 CHEBI:37453 biolink:ChemicalSubstance phenanthrenediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37453 GO:0001955 biolink:BiologicalProcess blood vessel maturation A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0001955 GO:0001956 biolink:BiologicalProcess positive regulation of neurotransmitter secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter. go-plus.json up regulation of neurotransmitter secretion|upregulation of neurotransmitter secretion|stimulation of neurotransmitter secretion|activation of neurotransmitter secretion|up-regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0001956 GO:0001957 biolink:BiologicalProcess intramembranous ossification Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. Wikipedia:Intramembranous_ossification go-plus.json dermal ossification|intramembranous bone ossification http://purl.obolibrary.org/obo/GO_0001957 GO:0001961 biolink:BiologicalProcess positive regulation of cytokine-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway. go-plus.json positive regulation of cytokine mediated signalling pathway|up regulation of cytokine mediated signaling pathway|activation of cytokine mediated signaling pathway|stimulation of cytokine mediated signaling pathway|up-regulation of cytokine mediated signaling pathway|positive regulation of cytokine and chemokine mediated signaling pathway|upregulation of cytokine mediated signaling pathway|positive regulation of cytokine mediated signaling pathway http://purl.obolibrary.org/obo/GO_0001961 GO:0001962 biolink:MolecularActivity alpha-1,3-galactosyltransferase activity Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage. go-plus.json isoglobotriaosylceramide synthase http://purl.obolibrary.org/obo/GO_0001962 GO:0001963 biolink:BiologicalProcess synaptic transmission, dopaminergic The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json dopaminergic synaptic transmission http://purl.obolibrary.org/obo/GO_0001963 GO:0001964 biolink:BiologicalProcess startle response An action or movement due to the application of a sudden unexpected stimulus. Wikipedia:Startle_reaction go-plus.json http://purl.obolibrary.org/obo/GO_0001964 GO:0001960 biolink:BiologicalProcess negative regulation of cytokine-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. go-plus.json down regulation of cytokine mediated signaling pathway|negative regulation of cytokine mediated signaling pathway|downregulation of cytokine mediated signaling pathway|down-regulation of cytokine mediated signaling pathway|inhibition of cytokine mediated signaling pathway|negative regulation of cytokine and chemokine mediated signaling pathway|negative regulation of cytokine mediated signalling pathway http://purl.obolibrary.org/obo/GO_0001960 CHEBI:37469 biolink:ChemicalSubstance 9,10-dihydrophenanthrene-9,10-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37469 chebi_ph7_3 CHEBI:37466 biolink:ChemicalSubstance O-phosphocorrinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37466 GO:0001969 biolink:BiologicalProcess regulation of activation of membrane attack complex Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. go-plus.json regulation of activation of the terminal complement cascade|regulation of activation of terminal complement complex|regulation of membrane attack complex formation|regulation of activation of MAC|regulation of membrane attack complex assembly|regulation of MAC formation|regulation of activation of TCC|regulation of MAC assembly http://purl.obolibrary.org/obo/GO_0001969 GO:0001965 biolink:MolecularActivity G-protein alpha-subunit binding Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide. go-plus.json G-alpha protein subunit binding http://purl.obolibrary.org/obo/GO_0001965 CHEBI:37464 biolink:ChemicalSubstance 3,4-dihydrophenanthrene-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37464 chebi_ph7_3 GO:0001966 biolink:BiologicalProcess thigmotaxis The directed movement of a motile cell or organism in response to touch. go-plus.json stereotaxis|taxis in response to touch stimulus|taxis in response to mechanical stimulus http://purl.obolibrary.org/obo/GO_0001966 CHEBI:37465 biolink:ChemicalSubstance (3R,4S)-3,4-dihydrophenanthrene-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37465 chebi_ph7_3 GO:0001967 biolink:BiologicalProcess suckling behavior Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast. go-plus.json nursing behavior http://purl.obolibrary.org/obo/GO_0001967 CHEBI:37462 biolink:ChemicalSubstance L-tagatose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37462 GO:0001968 biolink:MolecularActivity fibronectin binding Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids. go-plus.json http://purl.obolibrary.org/obo/GO_0001968 goslim_chembl CHEBI:37463 biolink:ChemicalSubstance ADP-D-ribose 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37463 GO:0098840 biolink:BiologicalProcess protein transport along microtubule The directed movement of a protein along a microtubule, mediated by motor proteins. go-plus.json microtubule-based protein transport http://purl.obolibrary.org/obo/GO_0098840 GO:0098841 biolink:BiologicalProcess protein localization to cell division site after cytokinesis A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0098841 GO:1902658 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902658 GO:1902659 biolink:BiologicalProcess regulation of glucose mediated signaling pathway Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway. go-plus.json regulation of glucose mediated signalling http://purl.obolibrary.org/obo/GO_1902659 GO:1902656 biolink:BiologicalProcess calcium ion import into cytosol The directed movement of calcium ion into a cytosol. go-plus.json calcium import into cytosol http://purl.obolibrary.org/obo/GO_1902656 GO:1902657 biolink:BiologicalProcess protein localization to prospore membrane A process in which a protein is transported to, or maintained in, a location within a prospore membrane. go-plus.json protein localisation to prospore membrane|establishment of protein localisation to prospore membrane|protein targeting to FSM|protein targeting to prospore membrane|protein targeting to forespore membrane|establishment of protein localization to prospore membrane|protein localization in prospore membrane|protein-prospore membrane targeting|establishment of protein localization in prospore membrane|protein localisation in prospore membrane|establishment of protein localisation in prospore membrane|protein targeting to ascospore-type prospore membrane http://purl.obolibrary.org/obo/GO_1902657 GO:1902654 biolink:BiologicalProcess aromatic primary alcohol metabolic process The chemical reactions and pathways involving aromatic primary alcohol. go-plus.json aromatic primary alcohol metabolism http://purl.obolibrary.org/obo/GO_1902654 GO:1902655 biolink:BiologicalProcess aromatic primary alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic primary alcohol. go-plus.json aromatic primary alcohol anabolism|aromatic primary alcohol synthesis|aromatic primary alcohol biosynthesis|aromatic primary alcohol formation http://purl.obolibrary.org/obo/GO_1902655 GO:1902652 biolink:BiologicalProcess secondary alcohol metabolic process The chemical reactions and pathways involving secondary alcohol. go-plus.json secondary alcohol metabolism http://purl.obolibrary.org/obo/GO_1902652 GO:1902653 biolink:BiologicalProcess secondary alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of secondary alcohol. go-plus.json secondary alcohol synthesis|secondary alcohol formation|secondary alcohol biosynthesis|secondary alcohol anabolism http://purl.obolibrary.org/obo/GO_1902653 GO:1902650 biolink:BiologicalProcess negative regulation of histone H2A-H2B dimer displacement Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A-H2B dimer displacement. go-plus.json downregulation of histone H2A-H2B dimer displacement|down regulation of histone H2A-H2B dimer displacement|inhibition of histone H2A-H2B dimer displacement|down-regulation of histone H2A-H2B dimer displacement http://purl.obolibrary.org/obo/GO_1902650 GO:0060230 biolink:MolecularActivity lipoprotein lipase activator activity Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0060230 GO:1902651 biolink:BiologicalProcess positive regulation of histone H2A-H2B dimer displacement Any process that activates or increases the frequency, rate or extent of histone H2A-H2B dimer displacement. go-plus.json up regulation of histone H2A-H2B dimer displacement|upregulation of histone H2A-H2B dimer displacement|up-regulation of histone H2A-H2B dimer displacement|activation of histone H2A-H2B dimer displacement http://purl.obolibrary.org/obo/GO_1902651 GO:0060231 biolink:BiologicalProcess mesenchymal to epithelial transition A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. go-plus.json epithelial cell differentiation from mesenchymal cell|mesenchymal-epithelial transition http://purl.obolibrary.org/obo/GO_0060231 GO:0060232 biolink:BiologicalProcess delamination The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0060232 GO:0035265 biolink:BiologicalProcess organ growth The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. go-plus.json http://purl.obolibrary.org/obo/GO_0035265 GO:1902660 biolink:BiologicalProcess negative regulation of glucose mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway. go-plus.json down-regulation of glucose mediated signaling pathway|down-regulation of glucose mediated signalling|negative regulation of glucose mediated signalling|downregulation of glucose mediated signaling pathway|inhibition of glucose mediated signalling|down regulation of glucose mediated signaling pathway|inhibition of glucose mediated signaling pathway|down regulation of glucose mediated signalling|downregulation of glucose mediated signalling http://purl.obolibrary.org/obo/GO_1902660 GO:0060233 biolink:BiologicalProcess oenocyte delamination The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0060233 GO:0035266 biolink:BiologicalProcess meristem growth The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0035266 GO:0035267 biolink:CellularComponent NuA4 histone acetyltransferase complex A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). go-plus.json TIP60 histone acetylase complex|TIP60 histone acetyltransferase complex http://purl.obolibrary.org/obo/GO_0035267 GO:0060234 biolink:BiologicalProcess neuroblast delamination The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0060234 GO:0035268 biolink:BiologicalProcess protein mannosylation The addition of a mannose residue to a protein acceptor molecule. go-plus.json protein amino acid mannosylation http://purl.obolibrary.org/obo/GO_0035268 GO:0060235 biolink:BiologicalProcess lens induction in camera-type eye Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens. go-plus.json http://purl.obolibrary.org/obo/GO_0060235 GO:0035269 biolink:BiologicalProcess protein O-linked mannosylation The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage. go-plus.json protein amino acid O-linked mannosylation http://purl.obolibrary.org/obo/GO_0035269 GO:0060236 biolink:BiologicalProcess regulation of mitotic spindle organization Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. go-plus.json regulation of mitotic spindle organisation|regulation of mitotic spindle organization and biogenesis http://purl.obolibrary.org/obo/GO_0060236 GO:0060237 biolink:BiologicalProcess regulation of fungal-type cell wall organization Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall. go-plus.json regulation of fungal-type cell wall organization and biogenesis|regulation of fungal-type cell wall organisation http://purl.obolibrary.org/obo/GO_0060237 GO:0060238 biolink:BiologicalProcess regulation of signal transduction involved in conjugation with cellular fusion Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0060238 GO:0060239 biolink:BiologicalProcess positive regulation of signal transduction involved in conjugation with cellular fusion Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0060239 GO:0098848 biolink:MolecularActivity alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane. RHEA:34707|EC:4.7.1.1 go-plus.json alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming) http://purl.obolibrary.org/obo/GO_0098848 GO:0098849 biolink:BiologicalProcess cellular detoxification of cadmium ion Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration. go-plus.json http://purl.obolibrary.org/obo/GO_0098849 GO:0098846 biolink:CellularComponent podocyte foot A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms. Wikipedia:Podocyte go-plus.json secondary podocyte projection|podocyte foot process|pedicel http://purl.obolibrary.org/obo/GO_0098846 GO:0035260 biolink:BiologicalProcess internal genitalia morphogenesis The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0035260 GO:0098847 biolink:MolecularActivity sequence-specific single stranded DNA binding Binding to single-stranded DNA of a specific nucleotide composition. go-plus.json http://purl.obolibrary.org/obo/GO_0098847 GO:0035261 biolink:BiologicalProcess external genitalia morphogenesis The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0035261 GO:0098844 biolink:CellularComponent postsynaptic endocytic zone membrane The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta. go-plus.json http://purl.obolibrary.org/obo/GO_0098844 goslim_synapse GO:0035262 biolink:BiologicalProcess gonad morphogenesis The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0035262 GO:0098845 biolink:CellularComponent postsynaptic endosome An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0098845 goslim_synapse GO:0035263 biolink:BiologicalProcess genital disc sexually dimorphic development The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed. go-plus.json http://purl.obolibrary.org/obo/GO_0035263 GO:0098842 biolink:CellularComponent postsynaptic early endosome An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling. go-plus.json http://purl.obolibrary.org/obo/GO_0098842 goslim_synapse GO:0035264 biolink:BiologicalProcess multicellular organism growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. go-plus.json body growth http://purl.obolibrary.org/obo/GO_0035264 GO:0098843 biolink:CellularComponent postsynaptic endocytic zone A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0098843 goslim_synapse GO:0098851 biolink:MolecularActivity double-stranded miRNA binding Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures. go-plus.json miRNA duplex binding http://purl.obolibrary.org/obo/GO_0098851 GO:0098852 biolink:CellularComponent lytic vacuole membrane The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098852 GO:0098850 biolink:CellularComponent extrinsic component of synaptic vesicle membrane The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098850 goslim_synapse GO:1902669 biolink:BiologicalProcess positive regulation of axon guidance Any process that activates or increases the frequency, rate or extent of axon guidance. go-plus.json upregulation of axon pathfinding|activation of axon guidance|up-regulation of axon growth cone guidance|up regulation of axon chemotaxis|up-regulation of axon pathfinding|activation of axon pathfinding|positive regulation of axon chemotaxis|upregulation of axon growth cone guidance|up-regulation of axon guidance|activation of axon chemotaxis|positive regulation of axon pathfinding|upregulation of axon guidance|up-regulation of axon chemotaxis|up regulation of axon growth cone guidance|up regulation of axon pathfinding|positive regulation of axon growth cone guidance|activation of axon growth cone guidance|up regulation of axon guidance|upregulation of axon chemotaxis http://purl.obolibrary.org/obo/GO_1902669 GO:2001204 biolink:BiologicalProcess regulation of osteoclast development Any process that modulates the frequency, rate or extent of osteoclast development. go-plus.json regulation of osteoclast cell development http://purl.obolibrary.org/obo/GO_2001204 GO:1902667 biolink:BiologicalProcess regulation of axon guidance Any process that modulates the frequency, rate or extent of axon guidance. go-plus.json regulation of axon chemotaxis|regulation of axon growth cone guidance|regulation of axon pathfinding http://purl.obolibrary.org/obo/GO_1902667 GO:2001205 biolink:BiologicalProcess negative regulation of osteoclast development Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development. go-plus.json negative regulation of osteoclast cell development http://purl.obolibrary.org/obo/GO_2001205 GO:1902668 biolink:BiologicalProcess negative regulation of axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance. go-plus.json down regulation of axon chemotaxis|down-regulation of axon guidance|downregulation of axon chemotaxis|inhibition of axon growth cone guidance|inhibition of axon guidance|negative regulation of axon chemotaxis|down regulation of axon growth cone guidance|down-regulation of axon chemotaxis|negative regulation of axon pathfinding|down-regulation of axon pathfinding|downregulation of axon growth cone guidance|down regulation of axon guidance|downregulation of axon pathfinding|inhibition of axon chemotaxis|downregulation of axon guidance|down-regulation of axon growth cone guidance|negative regulation of axon growth cone guidance|down regulation of axon pathfinding|inhibition of axon pathfinding http://purl.obolibrary.org/obo/GO_1902668 GO:1902665 biolink:BiologicalProcess response to isobutanol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus. go-plus.json process resulting in tolerance to isobutanol|response to 2-methylpropan-1-ol http://purl.obolibrary.org/obo/GO_1902665 GO:2001206 biolink:BiologicalProcess positive regulation of osteoclast development Any process that activates or increases the frequency, rate or extent of osteoclast development. go-plus.json positive regulation of osteoclast cell development http://purl.obolibrary.org/obo/GO_2001206 GO:1902666 biolink:BiologicalProcess obsolete protein localization to Mmi1 nuclear focus complex OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a Mmi1 nuclear focus complex. go-plus.json protein localization in Mmi1 nuclear focus complex|protein localisation to Mmi1 nuclear focus complex|protein localisation in Mmi1 nuclear focus complex http://purl.obolibrary.org/obo/GO_1902666 GO:2001207 biolink:BiologicalProcess regulation of transcription elongation from RNA polymerase I promoter Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter. go-plus.json regulation of RNA elongation from Pol I promoter http://purl.obolibrary.org/obo/GO_2001207 GO:1902663 biolink:BiologicalProcess negative regulation of peptidyl-L-cysteine S-palmitoylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation. go-plus.json inhibition of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|downregulation of peptidyl-L-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|down regulation of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down regulation of peptidyl-L-cysteine S-palmitoylation|inhibition of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-L-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down-regulation of peptidyl-cysteine S-palmitoylation|negative regulation of peptidyl-cysteine S-palmitoylation|down-regulation of peptidyl-L-cysteine S-palmitoylation|negative regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|downregulation of peptidyl-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_1902663 GO:2001208 biolink:BiologicalProcess negative regulation of transcription elongation by RNA polymerase I Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I. go-plus.json negative regulation of RNA elongation from Pol I promoter|negative regulation of transcription elongation from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_2001208 GO:1902664 biolink:BiologicalProcess positive regulation of peptidyl-L-cysteine S-palmitoylation Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation. go-plus.json upregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|upregulation of peptidyl-cysteine S-palmitoylation|upregulation of peptidyl-L-cysteine S-palmitoylation|upregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up-regulation of peptidyl-cysteine S-palmitoylation|activation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up-regulation of peptidyl-L-cysteine S-palmitoylation|activation of peptidyl-cysteine S-palmitoylation|activation of peptidyl-L-cysteine S-palmitoylation|up-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|positive regulation of peptidyl-cysteine S-palmitoylation|up-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up regulation of peptidyl-cysteine S-palmitoylation|up regulation of peptidyl-L-cysteine S-palmitoylation|positive regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_1902664 GO:2001209 biolink:BiologicalProcess positive regulation of transcription elongation from RNA polymerase I promoter Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter. go-plus.json positive regulation of RNA elongation from Pol I promoter http://purl.obolibrary.org/obo/GO_2001209 GO:1902661 biolink:BiologicalProcess positive regulation of glucose mediated signaling pathway Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway. go-plus.json up regulation of glucose mediated signalling|activation of glucose mediated signalling|positive regulation of glucose mediated signalling|up regulation of glucose mediated signaling pathway|up-regulation of glucose mediated signalling|upregulation of glucose mediated signaling pathway|upregulation of glucose mediated signalling|up-regulation of glucose mediated signaling pathway|activation of glucose mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902661 GO:1902662 biolink:BiologicalProcess regulation of peptidyl-L-cysteine S-palmitoylation Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation. go-plus.json regulation of peptidyl-cysteine S-palmitoylation|regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_1902662 GO:0060220 biolink:BiologicalProcess camera-type eye photoreceptor cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0060220 GO:0060221 biolink:BiologicalProcess retinal rod cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060221 GO:0035254 biolink:MolecularActivity glutamate receptor binding Binding to a glutamate receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0035254 goslim_chembl GO:1902670 biolink:MolecularActivity carbon dioxide binding Binding to carbon dioxide. go-plus.json CO2 binding http://purl.obolibrary.org/obo/GO_1902670 GO:1902671 biolink:CellularComponent left anterior basal body Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage). go-plus.json ciliary basal body of left anterior cilium|cilium basal body of left anterior flagellum|left anterior flagellum ciliary basal body|cilial basal body of left anterior cilium|microtubule basal body of left anterior flagellum|microtubule basal body of left anterior cilium|cilial basal body of left anterior flagellum|ciliary basal body of left anterior flagellum|cilium basal body of left anterior cilium http://purl.obolibrary.org/obo/GO_1902671 GO:0060222 biolink:BiologicalProcess regulation of retinal cone cell fate commitment Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060222 GO:0035255 biolink:MolecularActivity ionotropic glutamate receptor binding Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels. go-plus.json http://purl.obolibrary.org/obo/GO_0035255 GO:0035256 biolink:MolecularActivity G protein-coupled glutamate receptor binding Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor). go-plus.json metabotropic glutamate receptor binding|G-protein coupled glutamate receptor binding http://purl.obolibrary.org/obo/GO_0035256 GO:0060223 biolink:BiologicalProcess retinal rod cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0060223 GO:0060224 biolink:BiologicalProcess regulation of retinal rod cell fate commitment Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0060224 GO:0035257 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035257 GO:2001200 biolink:BiologicalProcess positive regulation of dendritic cell differentiation Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_2001200 GO:0060225 biolink:BiologicalProcess positive regulation of retinal rod cell fate commitment Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0060225 GO:0035258 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035258 GO:2001201 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001201 GO:0035259 biolink:MolecularActivity glucocorticoid receptor binding Binding to a glucocorticoid receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0035259 GO:0060226 biolink:BiologicalProcess negative regulation of retinal cone cell fate commitment Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060226 GO:0060227 biolink:BiologicalProcess Notch signaling pathway involved in camera-type eye photoreceptor fate commitment The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate. go-plus.json Notch signalling pathway involved in camera-type eye photoreceptor fate commitment http://purl.obolibrary.org/obo/GO_0060227 GO:2001202 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001202 GO:0060228 biolink:MolecularActivity phosphatidylcholine-sterol O-acyltransferase activator activity Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines. go-plus.json LCAT activator activity http://purl.obolibrary.org/obo/GO_0060228 GO:2001203 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001203 GO:0098859 biolink:CellularComponent actin filament bundle of actin-based cell projection A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0098859 GO:0060229 biolink:MolecularActivity lipase activator activity Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0060229 GO:0098857 biolink:CellularComponent membrane microdomain A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it. go-plus.json http://purl.obolibrary.org/obo/GO_0098857 GO:0098858 biolink:CellularComponent actin-based cell projection A cell projection supported by an assembly of actin filaments, and which lacks microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0098858 GO:0035250 biolink:MolecularActivity UDP-galactosyltransferase activity Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035250 GO:0098855 biolink:CellularComponent HCN channel complex A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart. go-plus.json K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|HCN4 channel complex|HCN3 channel complex|K/Na hyperpolarization-activated channel 3 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|HCN2 channel complex|HCN1 channel complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|potassium/sodium hyperpolarization-activated channel 3 complex http://purl.obolibrary.org/obo/GO_0098855 GO:0098856 biolink:BiologicalProcess intestinal lipid absorption Any process in which lipids are taken up from the contents of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0098856 GO:0035251 biolink:MolecularActivity UDP-glucosyltransferase activity Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule. Reactome:R-HSA-1912353|MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0035251 GO:0035252 biolink:MolecularActivity UDP-xylosyltransferase activity Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule. Reactome:R-HSA-5617138|Reactome:R-HSA-9638090|Reactome:R-HSA-6785668 go-plus.json http://purl.obolibrary.org/obo/GO_0035252 GO:0098853 biolink:CellularComponent endoplasmic reticulum-vacuole membrane contact site A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes. go-plus.json endoplasmic reticulum-vacuole membrane contact site|ER-vacuole membrane contact site http://purl.obolibrary.org/obo/GO_0098853 GO:0035253 biolink:CellularComponent ciliary rootlet A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm. go-plus.json cilium rootlet|cilial rootlet http://purl.obolibrary.org/obo/GO_0035253 GO:0098854 biolink:CellularComponent podocyte primary projection A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot. go-plus.json glomerular visceral epithelial cell primary projection|primary podocyte process|podocyte major process http://purl.obolibrary.org/obo/GO_0098854 GO:1902678 biolink:CellularComponent right caudal basal body Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage). go-plus.json ciliary basal body of right caudal flagellum|cilium basal body of right caudal cilium|cilial basal body of right caudal flagellum|microtubule basal body of right caudal flagellum|microtubule basal body of right caudal cilium|cilial basal body of right caudal cilium|right caudal flagellum ciliary basal body|cilium basal body of right caudal flagellum|ciliary basal body of right caudal cilium http://purl.obolibrary.org/obo/GO_1902678 GO:2001215 biolink:BiologicalProcess regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity Any process that modulates the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity. go-plus.json regulation of HMG-CoA reductase activity|regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_2001215 GO:1902679 biolink:BiologicalProcess negative regulation of RNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. go-plus.json inhibition of RNA biosynthetic process|inhibition of RNA biosynthesis|inhibition of RNA synthesis|inhibition of RNA formation|down regulation of RNA anabolism|downregulation of RNA anabolism|down regulation of RNA synthesis|negative regulation of RNA biosynthesis|down-regulation of RNA biosynthesis|down regulation of RNA formation|down-regulation of RNA biosynthetic process|downregulation of RNA synthesis|downregulation of RNA formation|down-regulation of RNA anabolism|negative regulation of RNA anabolism|downregulation of RNA biosynthesis|downregulation of RNA biosynthetic process|down-regulation of RNA synthesis|negative regulation of RNA synthesis|down regulation of RNA biosynthesis|down regulation of RNA biosynthetic process|down-regulation of RNA formation|inhibition of RNA anabolism|negative regulation of RNA formation http://purl.obolibrary.org/obo/GO_1902679 GO:2001216 biolink:BiologicalProcess negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity. go-plus.json negative regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|negative regulation of HMG-CoA reductase activity http://purl.obolibrary.org/obo/GO_2001216 GO:1902676 biolink:CellularComponent right ventral basal body Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage). go-plus.json cilial basal body of right ventral cilium|microtubule basal body of right ventral cilium|ciliary basal body of right ventral flagellum|cilium basal body of right ventral cilium|cilium basal body of right ventral flagellum|ciliary basal body of right ventral cilium|microtubule basal body of right ventral flagellum|right ventral flagellum ciliary basal body|cilial basal body of right ventral flagellum http://purl.obolibrary.org/obo/GO_1902676 GO:2001217 biolink:BiologicalProcess obsolete regulation of S/G2 transition of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of S/G2 transition of mitotic cell cycle. go-plus.json regulation of S/G2 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2001217 GO:1902677 biolink:CellularComponent left caudal basal body Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage). go-plus.json ciliary basal body of left caudal cilium|cilium basal body of left caudal flagellum|left caudal flagellum ciliary basal body|cilial basal body of left caudal cilium|microtubule basal body of left caudal flagellum|microtubule basal body of left caudal cilium|cilial basal body of left caudal flagellum|ciliary basal body of left caudal flagellum|cilium basal body of left caudal cilium http://purl.obolibrary.org/obo/GO_1902677 GO:2001218 biolink:BiologicalProcess obsolete negative regulation of S/G2 transition of mitotic cell cycle OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of S/G2 transition of mitotic cell cycle. go-plus.json negative regulation of S/G2 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2001218 GO:1902674 biolink:CellularComponent right posteriolateral basal body Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage). go-plus.json cilial basal body of right posteriolateral flagellum|cilium basal body of right posterolateral cilium|ciliary basal body of right posterolateral flagellum|cilium basal body of right posteriolateral cilium|ciliary basal body of right posteriolateral flagellum|cilial basal body of right posterolateral flagellum|microtubule basal body of right posterolateral cilium|microtubule basal body of right posterolateral flagellum|cilial basal body of right posterolateral cilium|ciliary basal body of right posteriolateral cilium|cilium basal body of right posteriolateral flagellum|right posteriolateral flagellum ciliary basal body|cilium basal body of right posterolateral flagellum|ciliary basal body of right posterolateral cilium|cilial basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral flagellum http://purl.obolibrary.org/obo/GO_1902674 GO:2001219 biolink:BiologicalProcess obsolete positive regulation of S/G2 transition of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of S/G2 transition of mitotic cell cycle. go-plus.json positive regulation of S/G2 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2001219 GO:0060250 biolink:BiologicalProcess germ-line stem-cell niche homeostasis A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion. go-plus.json maintenance of germ line stem cell niche|germ-line stem-cell niche maintenance|maintenance of germ-line stem-cell niche|maintenance of germ-line stem cell niche|maintenance of germ line stem-cell niche http://purl.obolibrary.org/obo/GO_0060250 GO:1902675 biolink:CellularComponent left ventral basal body Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage). go-plus.json microtubule basal body of left ventral cilium|cilium basal body of left ventral flagellum|cilial basal body of left ventral cilium|left ventral flagellum ciliary basal body|ciliary basal body of left ventral flagellum|ciliary basal body of left ventral cilium|cilial basal body of left ventral flagellum|cilium basal body of left ventral cilium|microtubule basal body of left ventral flagellum http://purl.obolibrary.org/obo/GO_1902675 GO:0060251 biolink:BiologicalProcess regulation of glial cell proliferation Any process that modulates the frequency, rate or extent of glial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0060251 GO:1902672 biolink:CellularComponent right anterior basal body Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage). go-plus.json cilium basal body of right anterior cilium|cilial basal body of right anterior flagellum|microtubule basal body of right anterior flagellum|microtubule basal body of right anterior cilium|cilial basal body of right anterior cilium|right anterior flagellum ciliary basal body|cilium basal body of right anterior flagellum|ciliary basal body of right anterior cilium|ciliary basal body of right anterior flagellum http://purl.obolibrary.org/obo/GO_1902672 GO:0060252 biolink:BiologicalProcess positive regulation of glial cell proliferation Any process that activates or increases the rate or extent of glial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0060252 GO:1902673 biolink:CellularComponent left posteriolateral basal body Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage). go-plus.json ciliary basal body of left posterolateral cilium|cilial basal body of left posteriolateral cilium|left posteriolateral flagellum ciliary basal body|cilium basal body of left posterolateral flagellum|cilium basal body of left posteriolateral flagellum|cilial basal body of left posterolateral cilium|ciliary basal body of left posteriolateral cilium|microtubule basal body of left posterolateral cilium|microtubule basal body of left posterolateral flagellum|ciliary basal body of left posteriolateral flagellum|cilial basal body of left posterolateral flagellum|cilium basal body of left posteriolateral cilium|cilium basal body of left posterolateral cilium|cilial basal body of left posteriolateral flagellum|ciliary basal body of left posterolateral flagellum|microtubule basal body of left posteriolateral flagellum|microtubule basal body of left posteriolateral cilium http://purl.obolibrary.org/obo/GO_1902673 GO:0060253 biolink:BiologicalProcess negative regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0060253 GO:0035243 biolink:MolecularActivity protein-arginine omega-N symmetric methyltransferase activity Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues. Reactome:R-HSA-6804383|RESID:AA0069|RESID:AA0067|EC:2.1.1.320|RHEA:48108 go-plus.json type II PRMT activity|type II protein arginine methyltransferase activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming) http://purl.obolibrary.org/obo/GO_0035243 GO:0060254 biolink:BiologicalProcess regulation of N-terminal protein palmitoylation Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0060254 GO:1902681 biolink:BiologicalProcess regulation of replication fork arrest at rDNA repeats Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats. go-plus.json regulation of replication fork arrest at ribosomal DNA repeats|regulation of replication fork blocking at rDNA repeats http://purl.obolibrary.org/obo/GO_1902681 GO:0060255 biolink:BiologicalProcess regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json http://purl.obolibrary.org/obo/GO_0060255 GO:1902682 biolink:BiologicalProcess protein localization to pericentric heterochromatin A process in which a protein is transported to, or maintained in the pericentric heterochromatin. go-plus.json protein localization to pericentric heterochromatin|protein localisation in centromeric heterochromatin http://purl.obolibrary.org/obo/GO_1902682 GO:0035244 biolink:MolecularActivity peptidyl-arginine C-methyltransferase activity Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0035244 GO:0060256 biolink:BiologicalProcess regulation of flocculation Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms. go-plus.json regulation of flocculation via cell wall protein-carbohydrate interaction http://purl.obolibrary.org/obo/GO_0060256 GO:0035245 biolink:BiologicalProcess peptidyl-arginine C-methylation The addition of a methyl group onto a carbon atom of an arginine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0035245 GO:2001210 biolink:BiologicalProcess regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway. go-plus.json regulation of acetate-mevalonate pathway|regulation of Ac-MVA pathway|regulation of isopentenyl diphosphate anabolism, mevalonate pathway|regulation of isopentenyl diphosphate synthesis, mevalonate pathway|regulation of isopentenyl diphosphate formation, mevalonate pathway http://purl.obolibrary.org/obo/GO_2001210 GO:1902680 biolink:BiologicalProcess positive regulation of RNA biosynthetic process Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. go-plus.json up regulation of RNA biosynthesis|up regulation of RNA biosynthetic process|activation of RNA synthesis|positive regulation of RNA synthesis|up regulation of RNA formation|activation of RNA formation|positive regulation of RNA formation|up-regulation of RNA anabolism|upregulation of RNA biosynthesis|upregulation of RNA biosynthetic process|up-regulation of RNA synthesis|up-regulation of RNA formation|upregulation of RNA anabolism|up-regulation of RNA biosynthesis|up-regulation of RNA biosynthetic process|upregulation of RNA synthesis|activation of RNA biosynthesis|activation of RNA biosynthetic process|upregulation of RNA formation|up regulation of RNA anabolism|activation of RNA anabolism|positive regulation of RNA anabolism|up regulation of RNA synthesis|positive regulation of RNA biosynthesis http://purl.obolibrary.org/obo/GO_1902680 GO:0060257 biolink:BiologicalProcess negative regulation of flocculation Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms. go-plus.json negative regulation of coflocculation http://purl.obolibrary.org/obo/GO_0060257 GO:0035246 biolink:BiologicalProcess peptidyl-arginine N-methylation The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0035246 GO:2001211 biolink:BiologicalProcess negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway. go-plus.json negative regulation of isopentenyl diphosphate synthesis, mevalonate pathway|negative regulation of isopentenyl diphosphate formation, mevalonate pathway|negative regulation of acetate-mevalonate pathway|negative regulation of isopentenyl diphosphate anabolism, mevalonate pathway|negative regulation of Ac-MVA pathway http://purl.obolibrary.org/obo/GO_2001211 GO:0035247 biolink:BiologicalProcess peptidyl-arginine omega-N-methylation The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein. RESID:AA0069|RESID:AA0068|RESID:AA0067 go-plus.json http://purl.obolibrary.org/obo/GO_0035247 GO:0060258 biolink:BiologicalProcess negative regulation of filamentous growth Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0060258 GO:2001212 biolink:BiologicalProcess regulation of vasculogenesis Any process that modulates the frequency, rate or extent of vasculogenesis. go-plus.json regulation of vascular morphogenesis http://purl.obolibrary.org/obo/GO_2001212 GO:0060259 biolink:BiologicalProcess regulation of feeding behavior Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food. go-plus.json regulation of feeding behaviour http://purl.obolibrary.org/obo/GO_0060259 GO:0035248 biolink:MolecularActivity alpha-1,4-N-acetylgalactosaminyltransferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage. go-plus.json alpha-1,4-GalNAc transferase activity http://purl.obolibrary.org/obo/GO_0035248 GO:0035249 biolink:BiologicalProcess synaptic transmission, glutamatergic The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json glutamatergic synaptic transmission http://purl.obolibrary.org/obo/GO_0035249 GO:2001213 biolink:BiologicalProcess negative regulation of vasculogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. go-plus.json negative regulation of vascular morphogenesis http://purl.obolibrary.org/obo/GO_2001213 GO:0098828 biolink:BiologicalProcess modulation of inhibitory postsynaptic potential Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. go-plus.json regulation of inhibitory postsynaptic potential http://purl.obolibrary.org/obo/GO_0098828 GO:2001214 biolink:BiologicalProcess positive regulation of vasculogenesis Any process that activates or increases the frequency, rate or extent of vasculogenesis. go-plus.json positive regulation of vascular morphogenesis http://purl.obolibrary.org/obo/GO_2001214 GO:0098829 biolink:BiologicalProcess intestinal folate absorption Uptake of folic into the blood by absorption from the small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0098829 GO:0098826 biolink:CellularComponent endoplasmic reticulum tubular network membrane The membrane of the endoplasmic reticulum tubular network. go-plus.json http://purl.obolibrary.org/obo/GO_0098826 GO:0098827 biolink:CellularComponent endoplasmic reticulum subcompartment A distinct region of the endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0098827 PO:0000191 biolink:OntologyClass synergid Cell, usually two in number, in the micropylar end of the embryo sac of angiosperms associated with the egg in the egg apparatus. go-plus.json 助細胞 (Japanese, exact)|sinérgida (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000191 GO:0098824 biolink:BiologicalProcess peptidyl-cysteine sulfation The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine. RESID:AA0171 go-plus.json http://purl.obolibrary.org/obo/GO_0098824 GO:0098825 biolink:BiologicalProcess peptidyl-histidine guanylation The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine. RESID:AA0325 go-plus.json http://purl.obolibrary.org/obo/GO_0098825 GO:0098822 biolink:BiologicalProcess peptidyl-cysteine modification to L-cysteine persulfide The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide. RESID:AA0269 go-plus.json http://purl.obolibrary.org/obo/GO_0098822 GO:0098823 biolink:BiologicalProcess peptidyl-cysteine modification to S-amindino-L-cysteine The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine. RESID:AA0335 go-plus.json http://purl.obolibrary.org/obo/GO_0098823 GO:0035240 biolink:MolecularActivity dopamine binding Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine. go-plus.json http://purl.obolibrary.org/obo/GO_0035240 GO:0035241 biolink:MolecularActivity protein-arginine omega-N monomethyltransferase activity Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine. RHEA:48100|RESID:AA0069|EC:2.1.1.321 go-plus.json S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming)|type III protein arginine methyltransferase activity http://purl.obolibrary.org/obo/GO_0035241 GO:0098820 biolink:CellularComponent trans-synaptic protein complex A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0098820 goslim_synapse GO:0035242 biolink:MolecularActivity protein-arginine omega-N asymmetric methyltransferase activity Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues. EC:2.1.1.319|RESID:AA0069|RHEA:48096|RESID:AA0068 go-plus.json type I protein arginine methyltransferase activity|type I PRMT activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega-dimethyl-L-arginine-forming) http://purl.obolibrary.org/obo/GO_0035242 GO:0098821 biolink:MolecularActivity BMP receptor activity Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0098821 GO:0098830 biolink:CellularComponent presynaptic endosome An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone. This organelle is believed to be involved in regeneration of synaptic vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0098830 goslim_synapse GO:1902689 biolink:BiologicalProcess negative regulation of NAD metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process. go-plus.json negative regulation of NAD phosphorylation and dephosphorylation|down regulation of nicotinamide adenine dinucleotide metabolism|down-regulation of NAD phosphorylation and dephosphorylation|inhibition of nicotinamide adenine dinucleotide metabolism|down regulation of NAD metabolic process|downregulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of oxidized nicotinamide adenine dinucleotide metabolism|downregulation of oxidized nicotinamide adenine dinucleotide metabolic process|inhibition of oxidized NAD metabolism|downregulation of NAD metabolic process|downregulation of oxidized NAD metabolic process|down-regulation of NAD (oxidized) metabolic process|negative regulation of NAD (oxidized) metabolic process|down regulation of oxidized nicotinamide adenine dinucleotide metabolic process|inhibition of oxidized nicotinamide adenine dinucleotide metabolic process|down regulation of NAD (oxidized) metabolism|inhibition of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of nicotinamide adenine dinucleotide metabolic process|down regulation of oxidized NAD metabolic process|inhibition of NAD phosphorylation and dephosphorylation|downregulation of NAD (oxidized) metabolism|inhibition of oxidized NAD metabolic process|down-regulation of NAD metabolic process|down-regulation of NAD metabolism|negative regulation of NAD metabolism|downregulation of NAD (oxidized) metabolic process|inhibition of nicotinamide adenine dinucleotide metabolic process|down regulation of oxidized NAD metabolism|down-regulation of nicotinamide adenine dinucleotide metabolism|down regulation of NAD phosphorylation and dephosphorylation|negative regulation of nicotinamide adenine dinucleotide metabolism|down regulation of NAD (oxidized) metabolic process|inhibition of NAD metabolic process|down regulation of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of NAD (oxidized) metabolism|inhibition of NAD (oxidized) metabolic process|negative regulation of NAD (oxidized) metabolism|downregulation of oxidized NAD metabolism|downregulation of NAD phosphorylation and dephosphorylation|downregulation of NAD metabolism|downregulation of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized nicotinamide adenine dinucleotide metabolic process|down regulation of NAD metabolism|downregulation of nicotinamide adenine dinucleotide metabolism|inhibition of NAD (oxidized) metabolism|inhibition of NAD metabolism|down regulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized NAD metabolic process|down-regulation of oxidized NAD metabolism|negative regulation of oxidized NAD metabolism|down-regulation of oxidized NAD metabolic process http://purl.obolibrary.org/obo/GO_1902689 GO:2001226 biolink:BiologicalProcess negative regulation of chloride transport Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001226 GO:2001227 biolink:MolecularActivity quercitrin binding Binding to quercitrin. go-plus.json http://purl.obolibrary.org/obo/GO_2001227 GO:1902687 biolink:CellularComponent glucosidase complex A protein complex which is capable of glucosidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902687 GO:2001228 biolink:BiologicalProcess regulation of response to gamma radiation Any process that modulates the frequency, rate or extent of response to gamma radiation. go-plus.json regulation of response to gamma ray|regulation of response to gamma-ray photon http://purl.obolibrary.org/obo/GO_2001228 GO:1902688 biolink:BiologicalProcess regulation of NAD metabolic process Any process that modulates the frequency, rate or extent of NAD metabolic process. go-plus.json regulation of oxidized nicotinamide adenine dinucleotide metabolic process|regulation of oxidized NAD metabolic process|regulation of NAD (oxidized) metabolism|regulation of NAD (oxidized) metabolic process|regulation of oxidized NAD metabolism|regulation of NAD phosphorylation and dephosphorylation|regulation of oxidized nicotinamide adenine dinucleotide metabolism|regulation of NAD metabolism|regulation of nicotinamide adenine dinucleotide metabolism|regulation of nicotinamide adenine dinucleotide metabolic process http://purl.obolibrary.org/obo/GO_1902688 GO:2001229 biolink:BiologicalProcess negative regulation of response to gamma radiation Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation. go-plus.json negative regulation of response to gamma-ray photon|negative regulation of response to gamma ray http://purl.obolibrary.org/obo/GO_2001229 GO:1902685 biolink:BiologicalProcess positive regulation of receptor localization to synapse Any process that activates or increases the frequency, rate or extent of receptor localization to synapse. go-plus.json up regulation of receptor localization to synapse|positive regulation of receptor localisation to synapse|up regulation of receptor localisation to synapse|upregulation of receptor localization to synapse|upregulation of receptor localisation to synapse|activation of receptor localization to synapse|up-regulation of receptor localization to synapse|up-regulation of receptor localisation to synapse|activation of receptor localisation to synapse http://purl.obolibrary.org/obo/GO_1902685 GO:1902686 biolink:BiologicalProcess mitochondrial outer membrane permeabilization involved in programmed cell death The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process. go-plus.json mitochondrial membrane permeability transition involved in nonapoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in regulated cell death|MPT involved in programmed cell death|positive regulation of mitochondrial membrane permeability involved in PCD|MPT involved in caspase-independent apoptosis|mitochondrial outer membrane permeabilization during programmed cell death|mitochondrial permeability transition involved in nonapoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in caspase-independent cell death|mitochondrial permeability transition involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in PCD|positive regulation of transport across mitochondrial membrane involved in regulated cell death|mitochondrial permeability transition involved in programmed cell death|mitochondrial membrane permeability transition involved in PCD|mitochondrial membrane permeability transition involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in caspase-independent apoptosis|MPT involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in programmed cell death|positive regulation of mitochondrial membrane permeability involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in caspase-independent apoptosis|mitochondrial membrane permeabilization involved in PCD|mitochondrial membrane permeabilization involved in non-apoptotic programmed cell death|mitochondrial membrane permeabilization involved in caspase-independent cell death|mitochondrial membrane permeabilization involved in programmed cell death|mitochondrial membrane permeabilization involved in regulated cell death|mitochondrial membrane permeabilization involved in caspase-independent apoptosis|positive regulation of transport across mitochondrial membrane involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in caspase-independent cell death|mitochondrial membrane permeability transition involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death|mitochondrial permeability transition involved in caspase-independent cell death|mitochondrion outer membrane permeabilization involved in programmed cell death|positive regulation of transport across mitochondrial membrane involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in regulated cell death|mitochondrial membrane permeabilization involved in nonapoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in non-apoptotic programmed cell death|MPT involved in caspase-independent cell death|positive regulation of transport across mitochondrial membrane involved in PCD|MPT involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in caspase-independent cell death|MPT involved in non-apoptotic programmed cell death|MPT involved in PCD|positive regulation of transport across mitochondrial membrane involved in programmed cell death http://purl.obolibrary.org/obo/GO_1902686 GO:0060240 biolink:BiologicalProcess negative regulation of signal transduction involved in conjugation with cellular fusion Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0060240 GO:1902683 biolink:BiologicalProcess regulation of receptor localization to synapse Any process that modulates the frequency, rate or extent of receptor localization to synapse. go-plus.json regulation of receptor localisation to synapse http://purl.obolibrary.org/obo/GO_1902683 GO:0060241 biolink:MolecularActivity lysozyme inhibitor activity Binds to and stops, prevents or reduces the activity of lysozyme. go-plus.json http://purl.obolibrary.org/obo/GO_0060241 GO:0060242 biolink:BiologicalProcess contact inhibition The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation. Wikipedia:Contact_inhibition go-plus.json detection of cell density by contact stimulus involved in contact inhibition|detection of cell density by contact stimulus http://purl.obolibrary.org/obo/GO_0060242 GO:1902684 biolink:BiologicalProcess negative regulation of receptor localization to synapse Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse. go-plus.json down-regulation of receptor localisation to synapse|negative regulation of receptor localisation to synapse|downregulation of receptor localization to synapse|down regulation of receptor localization to synapse|inhibition of receptor localization to synapse|downregulation of receptor localisation to synapse|down regulation of receptor localisation to synapse|inhibition of receptor localisation to synapse|down-regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902684 GO:0060243 biolink:BiologicalProcess negative regulation of cell growth involved in contact inhibition The negative regulation of cell growth in response to increased cell density. go-plus.json http://purl.obolibrary.org/obo/GO_0060243 GO:0035232 biolink:BiologicalProcess germ cell attraction The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target. go-plus.json http://purl.obolibrary.org/obo/GO_0035232 GO:1902692 biolink:BiologicalProcess regulation of neuroblast proliferation Any process that modulates the frequency, rate or extent of neuroblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_1902692 GO:0060244 biolink:BiologicalProcess negative regulation of cell proliferation involved in contact inhibition Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density. go-plus.json http://purl.obolibrary.org/obo/GO_0060244 GO:1902693 biolink:CellularComponent superoxide dismutase complex A protein complex which is capable of superoxide dismutase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902693 GO:0035233 biolink:BiologicalProcess germ cell repulsion The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0035233 GO:1902690 biolink:BiologicalProcess positive regulation of NAD metabolic process Any process that activates or increases the frequency, rate or extent of NAD metabolic process. go-plus.json up-regulation of NAD metabolic process|positive regulation of nicotinamide adenine dinucleotide metabolism|up-regulation of oxidized NAD metabolic process|activation of oxidized NAD metabolic process|upregulation of NAD (oxidized) metabolic process|up regulation of oxidized NAD metabolism|up regulation of nicotinamide adenine dinucleotide metabolism|activation of oxidized NAD metabolism|up regulation of NAD phosphorylation and dephosphorylation|upregulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of oxidized NAD metabolism|positive regulation of NAD phosphorylation and dephosphorylation|up-regulation of NAD (oxidized) metabolism|up regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of oxidized nicotinamide adenine dinucleotide metabolism|upregulation of NAD metabolism|upregulation of NAD metabolic process|positive regulation of oxidized nicotinamide adenine dinucleotide metabolism|positive regulation of oxidized nicotinamide adenine dinucleotide metabolic process|up-regulation of NAD (oxidized) metabolic process|up regulation of oxidized nicotinamide adenine dinucleotide metabolic process|activation of NAD phosphorylation and dephosphorylation|activation of NAD (oxidized) metabolic process|positive regulation of oxidized NAD metabolic process|upregulation of nicotinamide adenine dinucleotide metabolism|up regulation of nicotinamide adenine dinucleotide metabolic process|up regulation of oxidized NAD metabolic process|activation of nicotinamide adenine dinucleotide metabolic process|up-regulation of oxidized NAD metabolism|upregulation of NAD (oxidized) metabolism|positive regulation of nicotinamide adenine dinucleotide metabolic process|up-regulation of NAD phosphorylation and dephosphorylation|activation of NAD metabolism|up-regulation of NAD metabolism|up regulation of NAD metabolic process|up-regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of NAD metabolic process|upregulation of oxidized nicotinamide adenine dinucleotide metabolic process|positive regulation of NAD (oxidized) metabolic process|up-regulation of nicotinamide adenine dinucleotide metabolism|activation of nicotinamide adenine dinucleotide metabolism|up regulation of NAD (oxidized) metabolic process|upregulation of oxidized NAD metabolism|upregulation of oxidized NAD metabolic process|upregulation of NAD phosphorylation and dephosphorylation|up regulation of NAD (oxidized) metabolism|activation of NAD (oxidized) metabolism|up-regulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of NAD (oxidized) metabolism|upregulation of oxidized nicotinamide adenine dinucleotide metabolism|positive regulation of NAD metabolism|activation of oxidized nicotinamide adenine dinucleotide metabolic process|up-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|up regulation of NAD metabolism http://purl.obolibrary.org/obo/GO_1902690 GO:0060245 biolink:BiologicalProcess detection of cell density The series of events in which information about the density of cells in a population is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0060245 GO:0035234 biolink:BiologicalProcess ectopic germ cell programmed cell death Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. go-plus.json programmed cell death, ectopic germ cells|programmed cell death of ectopic germ cells http://purl.obolibrary.org/obo/GO_0035234 GO:2001220 biolink:BiologicalProcess obsolete negative regulation of G2 phase of mitotic cell cycle OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of G2 phase of mitotic cell cycle. go-plus.json negative regulation of G2 phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2001220 GO:0060246 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060246 GO:0035235 biolink:BiologicalProcess ionotropic glutamate receptor signaling pathway A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json ionotropic glutamate receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035235 GO:1902691 biolink:BiologicalProcess respiratory basal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell. go-plus.json airway basal cell differentiation http://purl.obolibrary.org/obo/GO_1902691 GO:2001221 biolink:BiologicalProcess obsolete positive regulation of G2 phase of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of G2 phase of mitotic cell cycle. go-plus.json positive regulation of G2 phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_2001221 GO:2001222 biolink:BiologicalProcess regulation of neuron migration Any process that modulates the frequency, rate or extent of neuron migration. go-plus.json regulation of neuronal migration|regulation of neuron chemotaxis|regulation of neuron guidance http://purl.obolibrary.org/obo/GO_2001222 GO:0060247 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060247 GO:0035236 biolink:MolecularActivity proctolin receptor activity Combining with the neuropeptide proctolin, to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035236 GO:2001223 biolink:BiologicalProcess negative regulation of neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration. go-plus.json negative regulation of neuron chemotaxis|negative regulation of neuron guidance|negative regulation of neuronal migration http://purl.obolibrary.org/obo/GO_2001223 GO:0060248 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060248 GO:0035237 biolink:MolecularActivity corazonin receptor activity Combining with the neuropeptide corazonin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0035237 GO:2001224 biolink:BiologicalProcess positive regulation of neuron migration Any process that activates or increases the frequency, rate or extent of neuron migration. go-plus.json positive regulation of neuron guidance|positive regulation of neuronal migration|positive regulation of neuron chemotaxis http://purl.obolibrary.org/obo/GO_2001224 GO:0060249 biolink:BiologicalProcess anatomical structure homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. go-plus.json anatomical structure maintenance http://purl.obolibrary.org/obo/GO_0060249 GO:0098839 biolink:CellularComponent postsynaptic density membrane The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. go-plus.json http://purl.obolibrary.org/obo/GO_0098839 goslim_synapse GO:0035238 biolink:BiologicalProcess vitamin A biosynthetic process The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids. go-plus.json vitamin A biosynthesis|vitamin A anabolism|vitamin A synthesis|vitamin A formation http://purl.obolibrary.org/obo/GO_0035238 GO:2001225 biolink:BiologicalProcess regulation of chloride transport Any process that modulates the frequency, rate or extent of chloride transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001225 GO:0035239 biolink:BiologicalProcess tube morphogenesis The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. go-plus.json http://purl.obolibrary.org/obo/GO_0035239 GO:0098837 biolink:CellularComponent postsynaptic recycling endosome A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane. In some cases at least, this recycling is activated by postsynaptic signalling and so can play a role in long term potentiation. go-plus.json postsynaptic endosomal recycling compartment|postsynaptic recycling outpost http://purl.obolibrary.org/obo/GO_0098837 goslim_synapse GO:0098838 biolink:BiologicalProcess folate transmembrane transport The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane. go-plus.json folic acid transmembrane transport|reduced folate transmembrane transport http://purl.obolibrary.org/obo/GO_0098838 GO:0098835 biolink:CellularComponent presynaptic endocytic zone membrane The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release. go-plus.json http://purl.obolibrary.org/obo/GO_0098835 goslim_synapse GO:0098836 biolink:CellularComponent cytoskeleton of dendritic spine The portion of the cytoskeleton that lies within a dendritic spine. The actin component of this cytoskeleton is involved in spine head remodelling in response to postsynaptic signalling. go-plus.json http://purl.obolibrary.org/obo/GO_0098836 GO:0098833 biolink:CellularComponent presynaptic endocytic zone A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis. It is especially enriched in endocytic proteins following intense activity. go-plus.json http://purl.obolibrary.org/obo/GO_0098833 goslim_synapse GO:0098834 biolink:CellularComponent presynaptic endocytic zone cytoplasmic component The cytoplasmic component of the presynaptic endocytic zone. go-plus.json cortex of presynaptic endocytic zone http://purl.obolibrary.org/obo/GO_0098834 goslim_synapse GO:0098831 biolink:CellularComponent presynaptic active zone cytoplasmic component A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles. go-plus.json presynaptic zone cortex|cortex of presynaptic active zone http://purl.obolibrary.org/obo/GO_0098831 goslim_synapse GO:0035230 biolink:CellularComponent cytoneme A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um. Wikipedia:Membrane_nanotube go-plus.json membrane nanotube http://purl.obolibrary.org/obo/GO_0035230 goslim_pir GO:0035231 biolink:BiologicalProcess cytoneme assembly Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell. go-plus.json cytoneme biogenesis http://purl.obolibrary.org/obo/GO_0035231 GO:0098832 biolink:CellularComponent peri-centrosomal recycling endosome A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0098832 GO:0098884 biolink:BiologicalProcess postsynaptic neurotransmitter receptor internalization A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle. go-plus.json postsynaptic neurotransmitter receptor endocytosis http://purl.obolibrary.org/obo/GO_0098884 goslim_synapse GO:0098885 biolink:BiologicalProcess modification of postsynaptic actin cytoskeleton Any process that modifies the structure of a postsynaptic actin cytoskeleton. go-plus.json postsynaptic actin cytoskeleton remodelling http://purl.obolibrary.org/obo/GO_0098885 goslim_synapse GO:0098882 biolink:MolecularActivity structural constituent of presynaptic active zone The action of a molecule that contributes to the structural integrity of a presynaptic active zone. go-plus.json structural constituent of active zone http://purl.obolibrary.org/obo/GO_0098882 goslim_synapse GO:0098883 biolink:BiologicalProcess synapse pruning A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. go-plus.json synapse clearance|synapse removal|synapse elimination|synapse disassembly http://purl.obolibrary.org/obo/GO_0098883 goslim_synapse GO:0098880 biolink:BiologicalProcess maintenance of postsynaptic specialization structure A process which maintains the organization and the arrangement of proteins in the presynaptic specialization. go-plus.json http://purl.obolibrary.org/obo/GO_0098880 goslim_synapse GO:0098881 biolink:BiologicalProcess exocytic insertion of neurotransmitter receptor to plasma membrane The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion. go-plus.json neurotransmitter receptor insertion http://purl.obolibrary.org/obo/GO_0098881 goslim_synapse GO:0035229 biolink:BiologicalProcess positive regulation of glutamate-cysteine ligase activity Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate. go-plus.json upregulation of glutamate-cysteine ligase activity|stimulation of glutamate-cysteine ligase activity|up-regulation of glutamate-cysteine ligase activity|activation of glutamate-cysteine ligase activity|up regulation of glutamate-cysteine ligase activity http://purl.obolibrary.org/obo/GO_0035229 GO:1902698 biolink:BiologicalProcess pentose catabolic process to butyrate The chemical reactions and pathways resulting in the breakdown of pentose to butyrate. go-plus.json acidogenesis|pentose degradation to butyrate|pentose catabolism to butyrate|pentose breakdown to butyrate http://purl.obolibrary.org/obo/GO_1902698 GO:0060270 biolink:BiologicalProcess main body follicle cell migration The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0060270 GO:1902699 biolink:BiologicalProcess pentose catabolic process to acetate The chemical reactions and pathways resulting in the breakdown of pentose to acetate. go-plus.json pentose catabolism to acetate|pentose degradation to acetate|acidogenesis|pentose breakdown to acetate http://purl.obolibrary.org/obo/GO_1902699 GO:0060271 biolink:BiologicalProcess cilium assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. Reactome:R-HSA-5617833.2 go-plus.json cilium morphogenesis|cilium formation|cilium assembly|cilium organization|microtubule-based flagellum assembly|cilium biogenesis|ciliogenesis http://purl.obolibrary.org/obo/GO_0060271 GO:1902696 biolink:BiologicalProcess glycine catabolic process to isobutanol The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol. go-plus.json glycine catabolism to isobutanol|glycine degradation to isobutanol|glycine breakdown to isobutanol http://purl.obolibrary.org/obo/GO_1902696 GO:0060272 biolink:BiologicalProcess embryonic skeletal joint morphogenesis The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0060272 GO:1902697 biolink:BiologicalProcess valine catabolic process to isobutanol The chemical reactions and pathways resulting in the breakdown of valine to isobutanol. go-plus.json valine degradation to isobutanol|valine breakdown to isobutanol|valine catabolism to isobutanol http://purl.obolibrary.org/obo/GO_1902697 GO:0060273 biolink:BiologicalProcess crying behavior The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0060273 GO:0060274 biolink:BiologicalProcess maintenance of stationary phase The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060274 GO:1902694 biolink:CellularComponent superoxide dismutase copper chaperone complex A protein complex which is capable of superoxide dismutase copper chaperone activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902694 GO:0060275 biolink:BiologicalProcess maintenance of stationary phase in response to starvation The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060275 GO:1902695 biolink:CellularComponent metallochaperone complex A protein complex which is capable of metallochaperone activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902695 GO:0035221 biolink:BiologicalProcess genital disc pattern formation The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc. go-plus.json http://purl.obolibrary.org/obo/GO_0035221 GO:0060276 biolink:BiologicalProcess maintenance of stationary phase in response to toxin The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0060276 GO:0060277 biolink:BiologicalProcess obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle OBSOLETE. Any process that stop, prevents or decreases transcription as part of the G1 phase of the mitotic cell cycle. go-plus.json negative regulation of transcription involved in G1 phase of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1 phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0060277 GO:0035222 biolink:BiologicalProcess wing disc pattern formation The process giving rise to the pattern of cell differentiation in the wing imaginal disc. go-plus.json http://purl.obolibrary.org/obo/GO_0035222 GO:0035223 biolink:BiologicalProcess leg disc pattern formation The process that gives rise to the patterns of cell differentiation in the leg imaginal disc. go-plus.json http://purl.obolibrary.org/obo/GO_0035223 GO:0060278 biolink:BiologicalProcess regulation of ovulation Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. go-plus.json http://purl.obolibrary.org/obo/GO_0060278 GO:0035224 biolink:BiologicalProcess genital disc anterior/posterior pattern formation The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium). go-plus.json http://purl.obolibrary.org/obo/GO_0035224 GO:0060279 biolink:BiologicalProcess positive regulation of ovulation Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. go-plus.json http://purl.obolibrary.org/obo/GO_0060279 GO:0035225 biolink:BiologicalProcess determination of genital disc primordium Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two. go-plus.json http://purl.obolibrary.org/obo/GO_0035225 GO:0035226 biolink:MolecularActivity glutamate-cysteine ligase catalytic subunit binding Binding to the catalytic subunit of glutamate-cysteine ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0035226 GO:0035227 biolink:BiologicalProcess regulation of glutamate-cysteine ligase activity Any process that modulates the activity of glutamate-cysteine ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0035227 GO:0035228 biolink:BiologicalProcess negative regulation of glutamate-cysteine ligase activity Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase. go-plus.json inhibition of glutamate-cysteine ligase activity|down-regulation of glutamate-cysteine ligase activity|downregulation of glutamate-cysteine ligase activity|down regulation of glutamate-cysteine ligase activity http://purl.obolibrary.org/obo/GO_0035228 GO:0098888 biolink:CellularComponent extrinsic component of presynaptic membrane The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic component of presynaptic plasma membrane http://purl.obolibrary.org/obo/GO_0098888 goslim_synapse GO:0098889 biolink:CellularComponent intrinsic component of presynaptic membrane The component of the presynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to presynaptic membrane http://purl.obolibrary.org/obo/GO_0098889 goslim_synapse GO:0098886 biolink:BiologicalProcess modification of dendritic spine Any process that modifies the structure of a dendritic spine. go-plus.json http://purl.obolibrary.org/obo/GO_0098886 GO:0035220 biolink:BiologicalProcess wing disc development Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura. go-plus.json http://purl.obolibrary.org/obo/GO_0035220 GO:0098887 biolink:BiologicalProcess neurotransmitter receptor transport, endosome to postsynaptic membrane The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. go-plus.json postsynaptic neurotransmitter receptor endosomal trafficking http://purl.obolibrary.org/obo/GO_0098887 goslim_synapse NCBITaxon:35510 biolink:OrganismalEntity Equus go-plus.json Equus subg. Equus|Equus http://purl.obolibrary.org/obo/NCBITaxon_35510 GO:0098895 biolink:CellularComponent postsynaptic endosome membrane The lipid bilayer surrounding a postsynaptic endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098895 goslim_synapse GO:0098896 biolink:CellularComponent postsynaptic early endosome membrane The lipid bilayer surrounding a postsynaptic early endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098896 goslim_synapse GO:0098893 biolink:CellularComponent extrinsic component of postsynaptic endocytic zone The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098893 goslim_synapse CHEBI:144542 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_144542 chebi_ph7_3 GO:0098894 biolink:CellularComponent extrinsic component of presynaptic endocytic zone membrane The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098894 goslim_synapse GO:0098891 biolink:CellularComponent extrinsic component of presynaptic active zone membrane The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098891 goslim_synapse CHEBI:144544 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(d18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_144544 chebi_ph7_3 GO:0098892 biolink:CellularComponent extrinsic component of postsynaptic specialization membrane The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098892 goslim_synapse GO:0098890 biolink:CellularComponent extrinsic component of postsynaptic membrane The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098890 goslim_synapse GO:0035218 biolink:BiologicalProcess leg disc development Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura. go-plus.json http://purl.obolibrary.org/obo/GO_0035218 GO:0035219 biolink:BiologicalProcess prothoracic disc development Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle. go-plus.json http://purl.obolibrary.org/obo/GO_0035219 GO:0060260 biolink:BiologicalProcess regulation of transcription initiation from RNA polymerase II promoter Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0060260 GO:0060261 biolink:BiologicalProcess positive regulation of transcription initiation from RNA polymerase II promoter Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0060261 GO:0060262 biolink:BiologicalProcess negative regulation of N-terminal protein palmitoylation Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0060262 GO:0060263 biolink:BiologicalProcess regulation of respiratory burst Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0060263 GO:0060264 biolink:BiologicalProcess regulation of respiratory burst involved in inflammatory response Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json regulation of respiratory burst involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0060264 GO:0060265 biolink:BiologicalProcess positive regulation of respiratory burst involved in inflammatory response Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json positive regulation of respiratory burst involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0060265 GO:0035210 biolink:BiologicalProcess prepupal development The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation. go-plus.json http://purl.obolibrary.org/obo/GO_0035210 GO:0035211 biolink:BiologicalProcess spermathecum morphogenesis The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk. go-plus.json http://purl.obolibrary.org/obo/GO_0035211 GO:0060266 biolink:BiologicalProcess negative regulation of respiratory burst involved in inflammatory response Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json negative regulation of respiratory burst involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_0060266 GO:0060267 biolink:BiologicalProcess positive regulation of respiratory burst Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0060267 GO:0035212 biolink:BiologicalProcess cell competition in a multicellular organism Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells. go-plus.json http://purl.obolibrary.org/obo/GO_0035212 GO:0060268 biolink:BiologicalProcess negative regulation of respiratory burst Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0060268 GO:0035213 biolink:BiologicalProcess clypeo-labral disc development The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite. go-plus.json development of structures derived from the clypeo-labral disc http://purl.obolibrary.org/obo/GO_0035213 GO:0060269 biolink:BiologicalProcess centripetally migrating follicle cell migration The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0060269 GO:0035214 biolink:BiologicalProcess eye-antennal disc development Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps. go-plus.json http://purl.obolibrary.org/obo/GO_0035214 GO:0035215 biolink:BiologicalProcess genital disc development Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia. go-plus.json http://purl.obolibrary.org/obo/GO_0035215 GO:0035216 biolink:BiologicalProcess haltere disc development Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. go-plus.json http://purl.obolibrary.org/obo/GO_0035216 GO:0035217 biolink:BiologicalProcess labial disc development Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis. go-plus.json http://purl.obolibrary.org/obo/GO_0035217 GO:0098899 biolink:CellularComponent spine apparatus lumen The volume enclosed by the spine apparatus membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098899 goslim_synapse NCBITaxon:35500 biolink:OrganismalEntity Pecora go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_35500 GO:0098897 biolink:CellularComponent spine apparatus membrane The lipid bilayer surrounding the spine apparatus. go-plus.json http://purl.obolibrary.org/obo/GO_0098897 goslim_synapse GO:0098898 biolink:CellularComponent dense core granule lumen The volume enclosed by the dense core granule membrane. go-plus.json dense core vesicle lumen http://purl.obolibrary.org/obo/GO_0098898 GO:0098862 biolink:CellularComponent cluster of actin-based cell projections A cell part consisting of multiple, closely packed actin-based cell projections. go-plus.json http://purl.obolibrary.org/obo/GO_0098862 GO:0098863 biolink:BiologicalProcess nuclear migration by microtubule mediated pushing forces The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0098863 GO:0098860 biolink:CellularComponent actin filament bundle of stereocilium A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098860 GO:0098861 biolink:CellularComponent actin filament bundle of filopodium A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex. go-plus.json http://purl.obolibrary.org/obo/GO_0098861 GO:0035207 biolink:BiologicalProcess negative regulation of hemocyte proliferation Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. go-plus.json down-regulation of hemocyte proliferation|negative regulation of arthropod blood cell proliferation|downregulation of hemocyte proliferation|down regulation of hemocyte proliferation|inhibition of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0035207 GO:0060290 biolink:BiologicalProcess transdifferentiation The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate. Wikipedia:Transdifferentiation go-plus.json http://purl.obolibrary.org/obo/GO_0060290 GO:0035208 biolink:BiologicalProcess positive regulation of hemocyte proliferation Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. go-plus.json positive regulation of arthropod blood cell proliferation|up regulation of hemocyte proliferation|upregulation of hemocyte proliferation|stimulation of hemocyte proliferation|activation of hemocyte proliferation|up-regulation of hemocyte proliferation http://purl.obolibrary.org/obo/GO_0035208 GO:0060291 biolink:BiologicalProcess long-term synaptic potentiation A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse. go-plus.json long-term potentiation|LTP http://purl.obolibrary.org/obo/GO_0060291 GO:0060292 biolink:BiologicalProcess long-term synaptic depression A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse. go-plus.json LTD|long term depression|long term synaptic depression http://purl.obolibrary.org/obo/GO_0060292 GO:0035209 biolink:BiologicalProcess pupal development The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis. go-plus.json http://purl.obolibrary.org/obo/GO_0035209 GO:0060293 biolink:CellularComponent germ plasm Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line. Wikipedia:Germ_plasm go-plus.json http://purl.obolibrary.org/obo/GO_0060293 GO:0060294 biolink:BiologicalProcess cilium movement involved in cell motility Movement of cilia mediated by motor proteins that contributes to the movement of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060294 GO:0060295 biolink:BiologicalProcess regulation of cilium movement involved in cell motility Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. go-plus.json http://purl.obolibrary.org/obo/GO_0060295 GO:0060296 biolink:BiologicalProcess regulation of cilium beat frequency involved in ciliary motility Any process that modulates the frequency of cilium beating involved in ciliary motility. go-plus.json http://purl.obolibrary.org/obo/GO_0060296 GO:0060297 biolink:BiologicalProcess regulation of sarcomere organization Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. go-plus.json regulation of sarcomere organisation http://purl.obolibrary.org/obo/GO_0060297 GO:0060298 biolink:BiologicalProcess positive regulation of sarcomere organization Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. go-plus.json positive regulation of sarcomere organisation http://purl.obolibrary.org/obo/GO_0060298 GO:0060299 biolink:BiologicalProcess negative regulation of sarcomere organization Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. go-plus.json negative regulation of sarcomere organisation http://purl.obolibrary.org/obo/GO_0060299 GO:0035200 biolink:BiologicalProcess leg disc anterior/posterior pattern formation The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc. go-plus.json http://purl.obolibrary.org/obo/GO_0035200 GO:0035201 biolink:BiologicalProcess leg disc anterior/posterior lineage restriction Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0035201 GO:0035202 biolink:BiologicalProcess tracheal pit formation in open tracheal system Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster. go-plus.json tracheal sac formation|tracheal placode invagination http://purl.obolibrary.org/obo/GO_0035202 GO:0035203 biolink:BiologicalProcess regulation of lamellocyte differentiation Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0035203 GO:0035204 biolink:BiologicalProcess negative regulation of lamellocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. go-plus.json down-regulation of lamellocyte differentiation|inhibition of lamellocyte differentiation|down regulation of lamellocyte differentiation|downregulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0035204 GO:0035205 biolink:BiologicalProcess positive regulation of lamellocyte differentiation Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. go-plus.json activation of lamellocyte differentiation|stimulation of lamellocyte differentiation|up-regulation of lamellocyte differentiation|upregulation of lamellocyte differentiation|up regulation of lamellocyte differentiation http://purl.obolibrary.org/obo/GO_0035205 GO:0035206 biolink:BiologicalProcess regulation of hemocyte proliferation Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. go-plus.json regulation of arthropod blood cell proliferation http://purl.obolibrary.org/obo/GO_0035206 GO:0098868 biolink:BiologicalProcess bone growth The increase in size or mass of a bone that contributes to the shaping of that bone. go-plus.json http://purl.obolibrary.org/obo/GO_0098868 GO:0098869 biolink:BiologicalProcess cellular oxidant detoxification Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. go-plus.json http://purl.obolibrary.org/obo/GO_0098869 GO:0098866 biolink:BiologicalProcess multivesicular body fusion to apical plasma membrane The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098866 GO:0098867 biolink:BiologicalProcess intramembranous bone growth The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. go-plus.json http://purl.obolibrary.org/obo/GO_0098867 GO:0098864 biolink:BiologicalProcess modification by symbiont of host tight cell-cell junction The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0098864 GO:0098865 biolink:BiologicalProcess modification by symbiont of host bicellular tight junctions The process in which an organism effects a change in the structure or function of its host bicellular tight junctions, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0098865 GO:0098873 biolink:BiologicalProcess neuronal action potential back-propagation Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma. go-plus.json http://purl.obolibrary.org/obo/GO_0098873 GO:0098874 biolink:BiologicalProcess spike train A series of sequential, propagated action potentials occurring in a single cell. go-plus.json spike-train|burst of action potentials http://purl.obolibrary.org/obo/GO_0098874 GO:0098871 biolink:CellularComponent postsynaptic actin cytoskeleton The actin cytoskeleton that is part of a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0098871 goslim_synapse GO:0098872 biolink:MolecularActivity G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse. go-plus.json G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration|G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels http://purl.obolibrary.org/obo/GO_0098872 goslim_synapse GO:0098870 biolink:BiologicalProcess action potential propagation The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold. go-plus.json http://purl.obolibrary.org/obo/GO_0098870 GO:0060280 biolink:BiologicalProcess negative regulation of ovulation Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. go-plus.json http://purl.obolibrary.org/obo/GO_0060280 GO:0060281 biolink:BiologicalProcess regulation of oocyte development Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060281 GO:0060282 biolink:BiologicalProcess positive regulation of oocyte development Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060282 GO:0060283 biolink:BiologicalProcess negative regulation of oocyte development Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060283 GO:0060284 biolink:BiologicalProcess regulation of cell development Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0060284 GO:0060285 biolink:BiologicalProcess cilium-dependent cell motility Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. go-plus.json microtubule-based flagellar cell motility|ciliary cell motility|cilium cell motility http://purl.obolibrary.org/obo/GO_0060285 GO:0060286 biolink:BiologicalProcess obsolete flagellar cell motility OBSOLETE. Cell motility due to the motion of one or more flagella. go-plus.json flagellar cell motility http://purl.obolibrary.org/obo/GO_0060286 GO:0060287 biolink:BiologicalProcess epithelial cilium movement involved in determination of left/right asymmetry The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves. go-plus.json cilium movement involved in determinationof L/R asymmetry|nodal cilium movement involved in determination of left/right asymmetry|Kuppfer's vesicle cilium movement involved in determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_0060287 GO:0060288 biolink:BiologicalProcess formation of a compartment boundary Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier. go-plus.json compartment boundary formation http://purl.obolibrary.org/obo/GO_0060288 GO:0060289 biolink:BiologicalProcess compartment boundary maintenance A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0060289 GO:0098879 biolink:MolecularActivity structural constituent of postsynaptic specialization The action of a molecule that contributes to the structural integrity of a postsynaptic specialization. go-plus.json http://purl.obolibrary.org/obo/GO_0098879 goslim_synapse GO:0098877 biolink:BiologicalProcess neurotransmitter receptor transport to plasma membrane The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0098877 goslim_synapse GO:0098878 biolink:CellularComponent neurotransmitter receptor complex Any protein complex that is capable of functioning as a neurotransmitter receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0098878 GO:0098875 biolink:CellularComponent epididymosome A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0098875 GO:0098876 biolink:BiologicalProcess vesicle-mediated transport to the plasma membrane The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0098876 GO:0050822 biolink:BiologicalProcess peptide stabilization Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded. go-plus.json peptide stabilisation|peptide stabilization activity http://purl.obolibrary.org/obo/GO_0050822 GO:0050823 biolink:BiologicalProcess peptide antigen stabilization Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded. go-plus.json peptide antigen stabilization activity http://purl.obolibrary.org/obo/GO_0050823 GO:0050820 biolink:BiologicalProcess positive regulation of coagulation Any process that activates or increases the frequency, rate or extent of coagulation. go-plus.json up-regulation of coagulation|upregulation of coagulation|positive regulation of clotting|up regulation of coagulation|activation of coagulation|stimulation of coagulation http://purl.obolibrary.org/obo/GO_0050820 GO:0050821 biolink:BiologicalProcess protein stabilization Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. go-plus.json protein stabilization activity|protein sequestering|lysosomal protein stabilization|protein stabilisation|positive regulation of protein stability http://purl.obolibrary.org/obo/GO_0050821 goslim_chembl GO:0050826 biolink:BiologicalProcess response to freezing Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius. go-plus.json antifreeze activity|ice nucleation inhibitor activity http://purl.obolibrary.org/obo/GO_0050826 GO:0050827 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050827 GO:0050824 biolink:MolecularActivity obsolete water binding OBSOLETE. Binding to water (H2O). go-plus.json http://purl.obolibrary.org/obo/GO_0050824 GO:0050825 biolink:MolecularActivity ice binding Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal. go-plus.json antifreeze activity|ice nucleation inhibitor activity|ice crystal binding|ice nucleation activity http://purl.obolibrary.org/obo/GO_0050825 GO:0050828 biolink:BiologicalProcess regulation of liquid surface tension Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid. go-plus.json regulation of surface tension of a liquid|surfactant activity http://purl.obolibrary.org/obo/GO_0050828 GO:0050829 biolink:BiologicalProcess defense response to Gram-negative bacterium Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism. go-plus.json defense response to Gram-negative bacteria|defence response to Gram-negative bacteria|Gram-negative antibacterial peptide activity|defence response to Gram-negative bacterium http://purl.obolibrary.org/obo/GO_0050829 GO:2001273 biolink:BiologicalProcess obsolete regulation of glucose import in response to insulin stimulus OBSOLETE. Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus. go-plus.json regulation of cellular glucose import in response to insulin stimulus http://purl.obolibrary.org/obo/GO_2001273 GO:2001274 biolink:BiologicalProcess obsolete negative regulation of glucose import in response to insulin stimulus OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus. go-plus.json negative regulation of cellular glucose import in response to insulin stimulus http://purl.obolibrary.org/obo/GO_2001274 GO:2001275 biolink:BiologicalProcess obsolete positive regulation of glucose import in response to insulin stimulus OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus. go-plus.json positive regulation of cellular glucose import in response to insulin stimulus http://purl.obolibrary.org/obo/GO_2001275 CHEBI:86338 biolink:ChemicalSubstance 3-hydroxydecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86338 GO:2001276 biolink:BiologicalProcess regulation of leucine biosynthetic process Any process that modulates the frequency, rate or extent of leucine biosynthetic process. go-plus.json regulation of leucine biosynthesis|regulation of leucine anabolism|regulation of leucine synthesis|regulation of leucine formation http://purl.obolibrary.org/obo/GO_2001276 CHEBI:86339 biolink:ChemicalSubstance D-5-monosubstituted hydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_86339 chebi_ph7_3 GO:2001277 biolink:BiologicalProcess negative regulation of leucine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process. go-plus.json negative regulation of leucine formation|negative regulation of leucine anabolism|negative regulation of leucine biosynthesis|negative regulation of leucine synthesis http://purl.obolibrary.org/obo/GO_2001277 GO:2001278 biolink:BiologicalProcess positive regulation of leucine biosynthetic process Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process. go-plus.json positive regulation of leucine anabolism|positive regulation of leucine synthesis|positive regulation of leucine formation|positive regulation of leucine biosynthesis http://purl.obolibrary.org/obo/GO_2001278 GO:2001279 biolink:BiologicalProcess regulation of unsaturated fatty acid biosynthetic process Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process. go-plus.json regulation of unsaturated fatty acid synthesis|regulation of unsaturated fatty acid formation|regulation of polyunsaturated fatty acid biosynthesis|regulation of fatty acid desaturation|regulation of unsaturated fatty acid biosynthesis|regulation of unsaturated fatty acid anabolism http://purl.obolibrary.org/obo/GO_2001279 GO:2001270 biolink:BiologicalProcess regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. go-plus.json regulation of effector caspase activity http://purl.obolibrary.org/obo/GO_2001270 GO:2001271 biolink:BiologicalProcess negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. go-plus.json negative regulation of effector caspase activity http://purl.obolibrary.org/obo/GO_2001271 NCBITaxon:35554 biolink:OrganismalEntity Geobacter sulfurreducens go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_35554 GO:2001272 biolink:BiologicalProcess positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. go-plus.json positive regulation of effector caspase activity http://purl.obolibrary.org/obo/GO_2001272 GO:0050830 biolink:BiologicalProcess defense response to Gram-positive bacterium Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. go-plus.json defence response to Gram-positive bacterium|defence response to Gram-positive bacteria|Gram-positive antibacterial peptide activity|defense response to Gram-positive bacteria http://purl.obolibrary.org/obo/GO_0050830 PO:0000112 biolink:OntologyClass shoot axis epidermis A portion of shoot system epidermis (PO:0006035) that is part of a shoot axis (PO:0025029). go-plus.json シュート軸表皮 (Japanese, exact)|epidermis del eje del tallo (Spanish, exact)|branch epidermis (narrow) http://purl.obolibrary.org/obo/PO_0000112 GO:0050833 biolink:MolecularActivity pyruvate transmembrane transporter activity Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other. Reactome:R-HSA-372342 go-plus.json monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity http://purl.obolibrary.org/obo/GO_0050833 PO:0000115 biolink:OntologyClass socket cell A shoot epidermal cell (PO:0025165) that surrounds a trichome (PO:0000282) and provides its support. go-plus.json ソケット細胞 (Japanese, exact)|trichome support cell (related)|célula de encaje (Spanish, exact)|cell located at the base of the trichome (related) http://purl.obolibrary.org/obo/PO_0000115 GO:0050834 biolink:BiologicalProcess molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide. RESID:AA0355 go-plus.json http://purl.obolibrary.org/obo/GO_0050834 GO:0050831 biolink:BiologicalProcess male-specific defense response to bacterium A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism. go-plus.json male-specific defence response to bacteria|male-specific antibacterial peptide activity|male-specific defense response to bacteria|male-specific defence response to bacterium http://purl.obolibrary.org/obo/GO_0050831 GO:0050832 biolink:BiologicalProcess defense response to fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. go-plus.json defence response to fungus|defense response to fungi|response to parasitic fungus|response to parasitic fungi|resistance response to pathogenic fungi|defense response to fungus, incompatible interaction|defence response to fungi|resistance response to pathogenic fungus http://purl.obolibrary.org/obo/GO_0050832 GO:0050837 biolink:BiologicalProcess peptide cross-linking via L-cysteinyl-L-selenocysteine The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P. RESID:AA0358 go-plus.json http://purl.obolibrary.org/obo/GO_0050837 CHEBI:62372 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-beta-L-talose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62372 chebi_ph7_3 GO:0050838 biolink:BiologicalProcess peptidyl-5-hydroxy-L-lysine trimethylation The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine. RESID:AA0359 go-plus.json http://purl.obolibrary.org/obo/GO_0050838 CHEBI:62370 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_62370 GO:0050835 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide. RESID:AA0356 go-plus.json http://purl.obolibrary.org/obo/GO_0050835 CHEBI:86320 biolink:ChemicalSubstance 1alpha,25-dihydroxyvitamin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_86320 chebi_ph7_3 GO:0050836 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide. RESID:AA0357 go-plus.json http://purl.obolibrary.org/obo/GO_0050836 CHEBI:86321 biolink:ChemicalSubstance 3-hydroxyoctanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86321 CHEBI:62377 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-hex-4-ulose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62377 chebi_ph7_3 CHEBI:86322 biolink:ChemicalSubstance alkaloid antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_86322 GO:0050839 biolink:MolecularActivity cell adhesion molecule binding Binding to a cell adhesion molecule. go-plus.json cell adhesion receptor activity|adhesive extracellular matrix constituent|cell adhesion molecule activity|CAM binding http://purl.obolibrary.org/obo/GO_0050839 NCBITaxon:203691 biolink:OrganismalEntity Spirochaetes go-plus.json Spirochaetae|Spirochaetota|Spirochaetaeota http://purl.obolibrary.org/obo/NCBITaxon_203691 CHEBI:86323 biolink:ChemicalSubstance conazole antifungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_86323 NCBITaxon:203692 biolink:OrganismalEntity Spirochaetia go-plus.json Spirochaetes|"Leptospiria" Cavalier-Smith 2020 http://purl.obolibrary.org/obo/NCBITaxon_203692 CHEBI:62375 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62375 chebi_ph7_3 CHEBI:86324 biolink:ChemicalSubstance quinolone antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_86324 GO:2001284 biolink:BiologicalProcess regulation of BMP secretion Any process that modulates the frequency, rate or extent of BMP secretion. go-plus.json regulation of BMP protein secretion|regulation of bone morphogenetic protein secretion http://purl.obolibrary.org/obo/GO_2001284 GO:2001285 biolink:BiologicalProcess negative regulation of BMP secretion Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion. go-plus.json negative regulation of bone morphogenetic protein secretion|negative regulation of BMP protein secretion http://purl.obolibrary.org/obo/GO_2001285 GO:2001286 biolink:BiologicalProcess regulation of caveolin-mediated endocytosis Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis. go-plus.json regulation of caveolae-mediated endocytosis|regulation of caveolin-dependent endocytosis|regulation of caveolae-dependent endocytosis http://purl.obolibrary.org/obo/GO_2001286 CHEBI:86327 biolink:ChemicalSubstance antifungal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_86327 GO:2001287 biolink:BiologicalProcess negative regulation of caveolin-mediated endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis. go-plus.json negative regulation of caveolin-dependent endocytosis|negative regulation of caveolae-dependent endocytosis|negative regulation of caveolae-mediated endocytosis http://purl.obolibrary.org/obo/GO_2001287 CHEBI:86328 biolink:ChemicalSubstance antifungal agrochemical go-plus.json http://purl.obolibrary.org/obo/CHEBI_86328 GO:2001288 biolink:BiologicalProcess positive regulation of caveolin-mediated endocytosis Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis. go-plus.json positive regulation of caveolin-dependent endocytosis|positive regulation of caveolae-dependent endocytosis|positive regulation of caveolae-mediated endocytosis http://purl.obolibrary.org/obo/GO_2001288 GO:2001289 biolink:BiologicalProcess lipid X metabolic process The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate. go-plus.json 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolic process|2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolism|Lipid X metabolic process|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolism|Lipid X metabolism|lipid X metabolism|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolism http://purl.obolibrary.org/obo/GO_2001289 GO:2001280 biolink:BiologicalProcess positive regulation of unsaturated fatty acid biosynthetic process Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process. go-plus.json positive regulation of unsaturated fatty acid anabolism|positive regulation of fatty acid desaturation|positive regulation of unsaturated fatty acid synthesis|positive regulation of unsaturated fatty acid biosynthesis|positive regulation of unsaturated fatty acid formation|positive regulation of polyunsaturated fatty acid biosynthesis http://purl.obolibrary.org/obo/GO_2001280 GO:2001281 biolink:BiologicalProcess regulation of muscle cell chemotaxis toward tendon cell Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell. go-plus.json regulation of muscle cell chemotaxis towards tendon cell|regulation of muscle cell attraction http://purl.obolibrary.org/obo/GO_2001281 GO:2001282 biolink:BiologicalProcess negative regulation of muscle cell chemotaxis toward tendon cell Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells. go-plus.json negative regulation of muscle cell attraction|arrest of muscle cell chemotaxis|negative regulation of muscle cell chemotaxis towards tendon cell http://purl.obolibrary.org/obo/GO_2001282 GO:2001283 biolink:BiologicalProcess Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. go-plus.json Roundabout signalling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signalling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signaling pathway involved in muscle cell attraction|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO signaling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signalling pathway involved in muscle cell attraction|ROBO/SLIT signaling pathway involved in muscle cell attraction|ROBO signaling pathway involved in muscle cell attraction|ROBO signaling pathway involved in muscle cell chemotaxis toward tendon cell|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signaling pathway involved in muscle cell chemotaxis towards tendon cell http://purl.obolibrary.org/obo/GO_2001283 GO:0050840 biolink:MolecularActivity extracellular matrix binding Binding to a component of the extracellular matrix. go-plus.json adhesive extracellular matrix constituent|extracellular matrix constituent binding http://purl.obolibrary.org/obo/GO_0050840 goslim_pir|goslim_chembl GO:0050841 biolink:BiologicalProcess peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine. RESID:AA0359 go-plus.json peptidyl-trimethyl-lysine hydroxylase activity|peptidyl trimethyl lysine hydroxylase activity http://purl.obolibrary.org/obo/GO_0050841 GO:0050844 biolink:BiologicalProcess peptidyl-selenocysteine modification The modification of peptidyl-selenocysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0050844 GO:0050845 biolink:BiologicalProcess teichuronic acid biosynthetic process The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria. go-plus.json teichuronic acid anabolism|teichuronic acid biosynthesis|teichuronic acid synthesis|teichuronic acid formation http://purl.obolibrary.org/obo/GO_0050845 GO:0050842 biolink:BiologicalProcess copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide. RESID:AA0355 go-plus.json http://purl.obolibrary.org/obo/GO_0050842 GO:0050843 biolink:BiologicalProcess S-adenosylmethionine catabolic process The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. go-plus.json S-adenosyl methionine catabolism|S-adenosylmethionine degradation|S-adenosyl methionine catabolic process|S-adenosylmethionine breakdown|SAM catabolic process|S-adenosylmethionine catabolism http://purl.obolibrary.org/obo/GO_0050843 GO:0050848 biolink:BiologicalProcess regulation of calcium-mediated signaling Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response. go-plus.json regulation of calcium-mediated signalling http://purl.obolibrary.org/obo/GO_0050848 NCBITaxon:203682 biolink:OrganismalEntity Planctomycetes go-plus.json Planctomycetota|Planctomycetaeota http://purl.obolibrary.org/obo/NCBITaxon_203682 CHEBI:62383 biolink:ChemicalSubstance 1D-myo-inositol 2-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62383 NCBITaxon:203683 biolink:OrganismalEntity Planctomycetia go-plus.json Planctomycetes|Planctomycea|Planctomycetacia http://purl.obolibrary.org/obo/NCBITaxon_203683 GO:0050849 biolink:BiologicalProcess negative regulation of calcium-mediated signaling Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling. go-plus.json down-regulation of calcium-mediated signaling|downregulation of calcium-mediated signaling|down regulation of calcium-mediated signaling|inhibition of calcium-mediated signaling|negative regulation of calcium-mediated signalling http://purl.obolibrary.org/obo/GO_0050849 GO:0050846 biolink:BiologicalProcess teichuronic acid metabolic process The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria. go-plus.json teichuronic acid metabolism http://purl.obolibrary.org/obo/GO_0050846 GO:0050847 biolink:BiologicalProcess progesterone receptor signaling pathway Any series of molecular signals generated as a consequence of a progesterone binding to its receptor. go-plus.json progesterone receptor signalling pathway http://purl.obolibrary.org/obo/GO_0050847 GO:2001295 biolink:BiologicalProcess malonyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A. go-plus.json malonyl-CoA synthesis|malonyl-CoA formation|malonyl-CoA biosynthesis|malonyl-CoA anabolism http://purl.obolibrary.org/obo/GO_2001295 GO:2001296 biolink:BiologicalProcess N(omega)-methyl-L-arginine metabolic process The chemical reactions and pathways involving N(omega)-methyl-L-arginine. go-plus.json N(omega)-methyl-L-arginine metabolism http://purl.obolibrary.org/obo/GO_2001296 CHEBI:86359 biolink:ChemicalSubstance L-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86359 GO:2001297 biolink:BiologicalProcess N(omega)-methyl-L-arginine catabolic process The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine. go-plus.json N(omega)-methyl-L-arginine catabolism|N(omega)-methyl-L-arginine degradation|N(omega)-methyl-L-arginine breakdown http://purl.obolibrary.org/obo/GO_2001297 GO:2001298 biolink:BiologicalProcess N(omega),N(omega)-dimethyl-L-arginine metabolic process The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group. go-plus.json N(omega),N(omega)-dimethyl-L-arginine metabolism http://purl.obolibrary.org/obo/GO_2001298 GO:2001299 biolink:BiologicalProcess N(omega),N(omega)-dimethyl-L-arginine catabolic process The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group. go-plus.json N(omega),N(omega)-dimethyl-L-arginine catabolism|N(omega),N(omega)-dimethyl-L-arginine degradation|N(omega),N(omega)-dimethyl-L-arginine breakdown http://purl.obolibrary.org/obo/GO_2001299 GO:2001290 biolink:BiologicalProcess hydroperoxide metabolic process The chemical reactions and pathways involving a hydroperoxide. go-plus.json hydroperoxide metabolism http://purl.obolibrary.org/obo/GO_2001290 GO:2001291 biolink:BiologicalProcess codeine metabolic process The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties. go-plus.json codeine metabolism http://purl.obolibrary.org/obo/GO_2001291 GO:2001292 biolink:BiologicalProcess codeine catabolic process The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties. go-plus.json codeine catabolism|codeine degradation|codeine breakdown http://purl.obolibrary.org/obo/GO_2001292 GO:2001293 biolink:BiologicalProcess malonyl-CoA metabolic process The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A. go-plus.json malonyl-CoA metabolism http://purl.obolibrary.org/obo/GO_2001293 GO:2001294 biolink:BiologicalProcess malonyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A. go-plus.json malonyl-CoA catabolism|malonyl-CoA degradation|malonyl-CoA breakdown http://purl.obolibrary.org/obo/GO_2001294 GO:1902609 biolink:BiologicalProcess (R)-2-hydroxy-alpha-linolenic acid biosynthetic process The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid. go-plus.json (R)-2-hydroxy-alpha-linolenic acid synthesis|(R)-2-hydroxy-alpha-linolenic acid formation|(R)-2-hydroxy-alpha-linolenic acid biosynthesis|2-hydroxy-octadecatrienoic acid biosynthesis|(R)-2-hydroxy-alpha-linolenic acid anabolism http://purl.obolibrary.org/obo/GO_1902609 GO:0050851 biolink:BiologicalProcess antigen receptor-mediated signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell. go-plus.json antigen receptor-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0050851 GO:0050852 biolink:BiologicalProcess T cell receptor signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. go-plus.json T lymphocyte receptor signalling pathway|T lymphocyte receptor signaling pathway|T-lymphocyte receptor signaling pathway|T-cell receptor signalling pathway|TCR signaling pathway|T-cell receptor signaling pathway|T-lymphocyte receptor signalling pathway http://purl.obolibrary.org/obo/GO_0050852 GO:1902607 biolink:BiologicalProcess negative regulation of large conductance calcium-activated potassium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity. go-plus.json downregulation of large conductance calcium-activated potassium channel activity|downregulation of large conductance KCa channels|down regulation of BK channel activity|down regulation of BK KCa channels|down regulation of BK calcium-activated potassium channel activity|down regulation of large conductance KCa channels|down regulation of large conductance calcium-activated potassium channel activity|downregulation of BK calcium-activated potassium channel activity|downregulation of BK KCa channels|downregulation of BK channel activity|inhibition of large conductance calcium-activated potassium channel activity|inhibition of large conductance KCa channels|negative regulation of BK calcium-activated potassium channel activity|down-regulation of BK KCa channels|negative regulation of BK channel activity|down-regulation of BK channel activity|negative regulation of BK KCa channels|down-regulation of BK calcium-activated potassium channel activity|inhibition of BK KCa channels|inhibition of BK calcium-activated potassium channel activity|down-regulation of large conductance KCa channels|down-regulation of large conductance calcium-activated potassium channel activity|negative regulation of large conductance KCa channels|inhibition of BK channel activity http://purl.obolibrary.org/obo/GO_1902607 GO:1902608 biolink:BiologicalProcess positive regulation of large conductance calcium-activated potassium channel activity Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity. go-plus.json positive regulation of large conductance KCa channels|up regulation of large conductance calcium-activated potassium channel activity|up regulation of large conductance KCa channels|upregulation of BK channel activity|upregulation of BK calcium-activated potassium channel activity|upregulation of BK KCa channels|upregulation of large conductance KCa channels|upregulation of large conductance calcium-activated potassium channel activity|up regulation of BK calcium-activated potassium channel activity|up regulation of BK KCa channels|up regulation of BK channel activity|positive regulation of BK channel activity|activation of BK calcium-activated potassium channel activity|positive regulation of BK KCa channels|activation of BK KCa channels|positive regulation of BK calcium-activated potassium channel activity|activation of BK channel activity|up-regulation of large conductance calcium-activated potassium channel activity|up-regulation of large conductance KCa channels|activation of large conductance calcium-activated potassium channel activity|activation of large conductance KCa channels|up-regulation of BK calcium-activated potassium channel activity|up-regulation of BK channel activity|up-regulation of BK KCa channels http://purl.obolibrary.org/obo/GO_1902608 GO:0050850 biolink:BiologicalProcess positive regulation of calcium-mediated signaling Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling. go-plus.json upregulation of calcium-mediated signaling|positive regulation of calcium-mediated signalling|stimulation of calcium-mediated signaling|activation of calcium-mediated signaling|up-regulation of calcium-mediated signaling|up regulation of calcium-mediated signaling http://purl.obolibrary.org/obo/GO_0050850 GO:0050855 biolink:BiologicalProcess regulation of B cell receptor signaling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. go-plus.json regulation of B lymphocyte receptor signalling pathway|regulation of B lymphocyte receptor signaling pathway|regulation of B-cell receptor signalling pathway|regulation of B-lymphocyte receptor signalling pathway|regulation of B-lymphocyte receptor signaling pathway|regulation of B-cell receptor signaling pathway|regulation of B cell receptor signalling pathway http://purl.obolibrary.org/obo/GO_0050855 GO:1902605 biolink:BiologicalProcess heterotrimeric G-protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex. go-plus.json heterotrimeric G-protein complex formation|heterotrimeric G-protein GTPase, beta-subunit assembly|heterotrimeric G-protein GTPase activity assembly|heterotrimeric G-protein GTPase, beta-subunit formation|heterotrimeric G-protein GTPase, alpha-subunit assembly|heterotrimeric G-protein GTPase, gamma-subunit formation|heterotrimeric G-protein GTPase, gamma-subunit assembly|heterotrimeric G-protein GTPase activity formation|heterotrimeric G-protein GTPase, alpha-subunit formation http://purl.obolibrary.org/obo/GO_1902605 GO:0050856 biolink:BiologicalProcess regulation of T cell receptor signaling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. go-plus.json regulation of T-cell receptor signalling pathway|regulation of T-lymphocyte receptor signalling pathway|regulation of T-lymphocyte receptor signaling pathway|regulation of TCR signaling pathway|regulation of T-cell receptor signaling pathway|regulation of T lymphocyte receptor signalling pathway|regulation of T lymphocyte receptor signaling pathway http://purl.obolibrary.org/obo/GO_0050856 GO:1902606 biolink:BiologicalProcess regulation of large conductance calcium-activated potassium channel activity Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity. go-plus.json regulation of large conductance KCa channels|regulation of BK calcium-activated potassium channel activity|regulation of BK KCa channels|regulation of BK channel activity http://purl.obolibrary.org/obo/GO_1902606 GO:0050853 biolink:BiologicalProcess B cell receptor signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell. go-plus.json B-cell receptor signalling pathway|B-lymphocyte receptor signaling pathway|B-lymphocyte receptor signalling pathway|B-cell receptor signaling pathway|B cell receptor signalling pathway|B lymphocyte receptor signalling pathway|B lymphocyte receptor signaling pathway http://purl.obolibrary.org/obo/GO_0050853 GO:1902603 biolink:BiologicalProcess carnitine transmembrane transport The directed movement of carnitine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1902603 GO:0050854 biolink:BiologicalProcess regulation of antigen receptor-mediated signaling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. go-plus.json regulation of antigen receptor mediated signalling pathway http://purl.obolibrary.org/obo/GO_0050854 GO:1902604 biolink:BiologicalProcess p-aminobenzoyl-glutamate transmembrane transport The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane. go-plus.json N-(4-aminobenzoyl)-L-glutamate transmembrane transport http://purl.obolibrary.org/obo/GO_1902604 GO:0050859 biolink:BiologicalProcess negative regulation of B cell receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. go-plus.json inhibition of B cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signaling pathway|negative regulation of B-cell receptor signalling pathway|negative regulation of B-cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signalling pathway|down regulation of B cell receptor signaling pathway|downregulation of B cell receptor signaling pathway|negative regulation of B cell receptor signalling pathway|negative regulation of B lymphocyte receptor signalling pathway|negative regulation of B lymphocyte receptor signaling pathway|down-regulation of B cell receptor signaling pathway http://purl.obolibrary.org/obo/GO_0050859 GO:1902601 biolink:BiologicalProcess silver ion transmembrane transport The directed movement of silver ion across a membrane. go-plus.json silver transmembrane transport http://purl.obolibrary.org/obo/GO_1902601 GO:1902602 biolink:BiologicalProcess aluminum ion transmembrane transport The process in which an aluminium ion is transported across a membrane. go-plus.json aluminum transmembrane transport|aluminium transmembrane transport|aluminium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1902602 CHEBI:86340 biolink:ChemicalSubstance L-5-monosubstituted hydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_86340 chebi_ph7_3 GO:0050857 biolink:BiologicalProcess positive regulation of antigen receptor-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. go-plus.json up regulation of antigen receptor-mediated signaling pathway|activation of antigen receptor-mediated signaling pathway|stimulation of antigen receptor-mediated signaling pathway|up-regulation of antigen receptor-mediated signaling pathway|upregulation of antigen receptor-mediated signaling pathway|positive regulation of antigen receptor mediated signalling pathway http://purl.obolibrary.org/obo/GO_0050857 GO:1902600 biolink:BiologicalProcess proton transmembrane transport The directed movement of a proton across a membrane. go-plus.json hydrogen transport|ATP hydrolysis coupled proton transport|hydrogen ion transport|hydrogen ion transmembrane transport|proton transmembrane transport|passive proton transport, down the electrochemical gradient|hydrogen transmembrane transport|proton transport http://purl.obolibrary.org/obo/GO_1902600 goslim_pir GO:0050858 biolink:BiologicalProcess negative regulation of antigen receptor-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. go-plus.json down-regulation of antigen receptor-mediated signaling pathway|inhibition of antigen receptor-mediated signaling pathway|negative regulation of antigen receptor mediated signalling pathway|down regulation of antigen receptor-mediated signaling pathway|downregulation of antigen receptor-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0050858 GO:0050862 biolink:BiologicalProcess positive regulation of T cell receptor signaling pathway Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. go-plus.json upregulation of T cell receptor signaling pathway|positive regulation of T-lymphocyte receptor signalling pathway|positive regulation of T lymphocyte receptor signaling pathway|up regulation of T cell receptor signaling pathway|activation of T cell receptor signaling pathway|stimulation of T cell receptor signaling pathway|positive regulation of T cell receptor signalling pathway|positive regulation of T lymphocyte receptor signalling pathway|positive regulation of T-lymphocyte receptor signaling pathway|positive regulation of TCR signaling pathway|up-regulation of T cell receptor signaling pathway|positive regulation of T-cell receptor signaling pathway http://purl.obolibrary.org/obo/GO_0050862 GO:0050863 biolink:BiologicalProcess regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell activation. go-plus.json regulation of T-cell activation|regulation of T lymphocyte activation|regulation of T-lymphocyte activation http://purl.obolibrary.org/obo/GO_0050863 GO:0050860 biolink:BiologicalProcess negative regulation of T cell receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. go-plus.json negative regulation of T-cell receptor signaling pathway|down regulation of T cell receptor signaling pathway|negative regulation of T-lymphocyte receptor signalling pathway|downregulation of T cell receptor signaling pathway|negative regulation of T lymphocyte receptor signaling pathway|negative regulation of T cell receptor signalling pathway|negative regulation of T lymphocyte receptor signalling pathway|down-regulation of T cell receptor signaling pathway|inhibition of T cell receptor signaling pathway|negative regulation of T-lymphocyte receptor signaling pathway|negative regulation of TCR signaling pathway http://purl.obolibrary.org/obo/GO_0050860 GO:1902618 biolink:BiologicalProcess cellular response to fluoride Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902618 GO:0050861 biolink:BiologicalProcess positive regulation of B cell receptor signaling pathway Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. go-plus.json positive regulation of B cell receptor signalling pathway|activation of B cell receptor signaling pathway|stimulation of B cell receptor signaling pathway|positive regulation of B lymphocyte receptor signalling pathway|positive regulation of B-lymphocyte receptor signaling pathway|up-regulation of B cell receptor signaling pathway|positive regulation of B-cell receptor signaling pathway|positive regulation of B-cell receptor signalling pathway|upregulation of B cell receptor signaling pathway|positive regulation of B-lymphocyte receptor signalling pathway|positive regulation of B lymphocyte receptor signaling pathway|up regulation of B cell receptor signaling pathway http://purl.obolibrary.org/obo/GO_0050861 GO:1902619 biolink:BiologicalProcess regulation of microtubule minus-end binding Any process that modulates the frequency, rate or extent of microtubule minus-end binding. go-plus.json http://purl.obolibrary.org/obo/GO_1902619 GO:1902616 biolink:BiologicalProcess acyl carnitine transmembrane transport The process in which acyl carnitine is transported across a membrane. go-plus.json O-acylcarnitine transmembrane transport http://purl.obolibrary.org/obo/GO_1902616 GO:0050866 biolink:BiologicalProcess negative regulation of cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. go-plus.json down regulation of cell activation|downregulation of cell activation|down-regulation of cell activation|inhibition of cell activation http://purl.obolibrary.org/obo/GO_0050866 GO:1902617 biolink:BiologicalProcess response to fluoride Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902617 GO:0050867 biolink:BiologicalProcess positive regulation of cell activation Any process that activates or increases the frequency, rate or extent of activation. go-plus.json upregulation of cell activation|up regulation of cell activation|activation of cell activation|stimulation of cell activation|up-regulation of cell activation http://purl.obolibrary.org/obo/GO_0050867 GO:1902614 biolink:BiologicalProcess positive regulation of anti-Mullerian hormone signaling pathway Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway. go-plus.json up regulation of anti-Mullerian hormone signaling pathway|upregulation of anti-Mullerian hormone signaling pathway|up-regulation of anti-Mullerian hormone signaling pathway|activation of anti-Mullerian hormone signaling pathway http://purl.obolibrary.org/obo/GO_1902614 GO:0050864 biolink:BiologicalProcess regulation of B cell activation Any process that modulates the frequency, rate or extent of B cell activation. go-plus.json regulation of B lymphocyte activation|regulation of B-lymphocyte activation|regulation of B-cell activation http://purl.obolibrary.org/obo/GO_0050864 GO:1902615 biolink:BiologicalProcess immune response involved in response to exogenous dsRNA Any immune response that is involved in response to exogenous dsRNA. go-plus.json immune response involved in response to viral dsRNA|immune response involved in response to exogenous double-stranded RNA http://purl.obolibrary.org/obo/GO_1902615 GO:0050865 biolink:BiologicalProcess regulation of cell activation Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0050865 GO:1902612 biolink:BiologicalProcess regulation of anti-Mullerian hormone signaling pathway Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1902612 GO:2001237 biolink:BiologicalProcess negative regulation of extrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway. go-plus.json negative regulation of extrinsic apoptosis|negative regulation of extrinsic apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001237 GO:1902613 biolink:BiologicalProcess negative regulation of anti-Mullerian hormone signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway. go-plus.json down-regulation of anti-Mullerian hormone signaling pathway|downregulation of anti-Mullerian hormone signaling pathway|down regulation of anti-Mullerian hormone signaling pathway|inhibition of anti-Mullerian hormone signaling pathway http://purl.obolibrary.org/obo/GO_1902613 GO:2001238 biolink:BiologicalProcess positive regulation of extrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway. go-plus.json positive regulation of extrinsic apoptosis|positive regulation of extrinsic apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001238 GO:0050868 biolink:BiologicalProcess negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. go-plus.json down-regulation of T cell activation|inhibition of T cell activation|negative regulation of T-lymphocyte activation|negative regulation of T-cell activation|down regulation of T cell activation|downregulation of T cell activation|negative regulation of T lymphocyte activation http://purl.obolibrary.org/obo/GO_0050868 GO:2001239 biolink:BiologicalProcess regulation of extrinsic apoptotic signaling pathway in absence of ligand Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. go-plus.json regulation of extrinsic apoptotic signalling pathway in absence of ligand|regulation of dependence receptor signaling pathway|regulation of extrinsic apoptosis in absence of ligand http://purl.obolibrary.org/obo/GO_2001239 GO:1902610 biolink:BiologicalProcess response to N-phenylthiourea Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902610 GO:0050869 biolink:BiologicalProcess negative regulation of B cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. go-plus.json negative regulation of B-cell activation|down regulation of B cell activation|downregulation of B cell activation|negative regulation of B lymphocyte activation|down-regulation of B cell activation|inhibition of B cell activation|negative regulation of B-lymphocyte activation http://purl.obolibrary.org/obo/GO_0050869 GO:1902611 biolink:BiologicalProcess cellular response to N-phenylthiourea Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902611 CHEBI:86375 biolink:ChemicalSubstance (11Z)-hexadec-11-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86375 CHEBI:86376 biolink:ChemicalSubstance (10E,12Z)-hexadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86376 CHEBI:86377 biolink:ChemicalSubstance 5beta-dihydroepitestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_86377 chebi_ph7_3 CHEBI:86378 biolink:ChemicalSubstance (25R)-3beta-hydroxycholest-5-en-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86378 CHEBI:86379 biolink:ChemicalSubstance alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86379 GO:2001230 biolink:BiologicalProcess positive regulation of response to gamma radiation Any process that activates or increases the frequency, rate or extent of response to gamma radiation. go-plus.json positive regulation of response to gamma ray|positive regulation of response to gamma-ray photon http://purl.obolibrary.org/obo/GO_2001230 GO:2001231 biolink:BiologicalProcess regulation of protein localization to prospore membrane Any process that modulates the frequency, rate or extent of protein localization to prospore membrane. go-plus.json regulation of protein targeting to prospore membrane|regulation of protein targeting to forespore membrane|regulation of protein-prospore membrane targeting|regulation of protein localisation to prospore membrane|regulation of protein targeting to ascospore-type prospore membrane|regulation of protein targeting to FSM http://purl.obolibrary.org/obo/GO_2001231 GO:2001232 biolink:BiologicalProcess positive regulation of protein localization to prospore membrane Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane. go-plus.json positive regulation of protein targeting to forespore membrane|positive regulation of protein-prospore membrane targeting|positive regulation of protein targeting to FSM|positive regulation of protein localisation to prospore membrane|positive regulation of protein targeting to ascospore-type prospore membrane|positive regulation of protein targeting to prospore membrane http://purl.obolibrary.org/obo/GO_2001232 GO:0098808 biolink:MolecularActivity mRNA cap binding Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0098808 GO:2001233 biolink:BiologicalProcess regulation of apoptotic signaling pathway Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. go-plus.json regulation of apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001233 GO:2001234 biolink:BiologicalProcess negative regulation of apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. go-plus.json negative regulation of apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001234 GO:0098809 biolink:MolecularActivity nitrite reductase activity Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0098809 GO:2001235 biolink:BiologicalProcess positive regulation of apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. go-plus.json positive regulation of apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001235 GO:0098806 biolink:BiologicalProcess deadenylation involved in gene silencing by miRNA Shortening of the poly(A) tail of a nuclear-transcribed mRNA following miRNA binding to mRNA, resulting in destabilization of the mRNA and a reduction in the efficiency of its translation. go-plus.json http://purl.obolibrary.org/obo/GO_0098806 GO:2001236 biolink:BiologicalProcess regulation of extrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway. go-plus.json regulation of extrinsic apoptotic signalling pathway|regulation of extrinsic apoptosis http://purl.obolibrary.org/obo/GO_2001236 GO:0098807 biolink:CellularComponent chloroplast thylakoid membrane protein complex A protein complex that is part of a chloroplast thylakoid membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098807 GO:0098804 biolink:CellularComponent non-motile cilium membrane The portion of the plasma membrane surrounding a non-motile cilium. go-plus.json nonmotile primary cilium membrane http://purl.obolibrary.org/obo/GO_0098804 GO:0098805 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0098805 GO:0098802 biolink:CellularComponent plasma membrane signaling receptor complex Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0098802 gocheck_do_not_manually_annotate GO:0098803 biolink:CellularComponent respiratory chain complex Any protein complex that is part of a respiratory chain. go-plus.json http://purl.obolibrary.org/obo/GO_0098803 GO:0098800 biolink:CellularComponent inner mitochondrial membrane protein complex Any protein complex that is part of the inner mitochondrial membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0098800 GO:0098801 biolink:BiologicalProcess regulation of renal system process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. go-plus.json http://purl.obolibrary.org/obo/GO_0098801 GO:0050873 biolink:BiologicalProcess brown fat cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. go-plus.json brown adipocyte differentiation|brown adipocyte cell differentiation http://purl.obolibrary.org/obo/GO_0050873 GO:0050874 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050874 GO:0050871 biolink:BiologicalProcess positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell activation. go-plus.json positive regulation of B-lymphocyte activation|up-regulation of B cell activation|positive regulation of B-cell activation|upregulation of B cell activation|positive regulation of B lymphocyte activation|up regulation of B cell activation|activation of B cell activation|stimulation of B cell activation http://purl.obolibrary.org/obo/GO_0050871 GO:1902629 biolink:BiologicalProcess regulation of mRNA stability involved in cellular response to UV Any regulation of mRNA stability that is involved in cellular response to UV. go-plus.json regulation of mRNA stability involved in cellular response to UV radiation stimulus|regulation of mRNA stability involved in cellular response to ultraviolet light stimulus|regulation of mRNA stability involved in cellular response to ultraviolet radiation stimulus|regulation of mRNA stability involved in cellular response to UV light stimulus http://purl.obolibrary.org/obo/GO_1902629 GO:0050872 biolink:BiologicalProcess white fat cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. go-plus.json white adipocyte cell differentiation|white adipocyte differentiation http://purl.obolibrary.org/obo/GO_0050872 GO:1902627 biolink:BiologicalProcess regulation of assembly of large subunit precursor of preribosome Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome. go-plus.json regulation of preribosome, large subunit precursor formation|regulation of 66S preribosome formation|regulation of 66S preribosome assembly http://purl.obolibrary.org/obo/GO_1902627 GO:0050877 biolink:BiologicalProcess nervous system process A organ system process carried out by any of the organs or tissues of neurological system. go-plus.json neurological system process|neurophysiological process|pan-neural process http://purl.obolibrary.org/obo/GO_0050877 goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_pir|goslim_generic GO:1902628 biolink:BiologicalProcess positive regulation of assembly of large subunit precursor of preribosome Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome. go-plus.json activation of assembly of large subunit precursor of preribosome|up-regulation of assembly of large subunit precursor of preribosome|up regulation of 66S preribosome formation|upregulation of 66S preribosome assembly|positive regulation of 66S preribosome formation|upregulation of preribosome, large subunit precursor formation|activation of 66S preribosome formation|up-regulation of 66S preribosome assembly|up regulation of assembly of large subunit precursor of preribosome|up-regulation of 66S preribosome formation|activation of preribosome, large subunit precursor formation|up-regulation of preribosome, large subunit precursor formation|activation of 66S preribosome assembly|positive regulation of 66S preribosome assembly|upregulation of assembly of large subunit precursor of preribosome|upregulation of 66S preribosome formation|up regulation of 66S preribosome assembly|positive regulation of preribosome, large subunit precursor formation|up regulation of preribosome, large subunit precursor formation http://purl.obolibrary.org/obo/GO_1902628 GO:0050878 biolink:BiologicalProcess regulation of body fluid levels Any process that modulates the levels of body fluids. go-plus.json http://purl.obolibrary.org/obo/GO_0050878 goslim_pir GO:1902625 biolink:BiologicalProcess obsolete negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of induction of conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_1902625 GO:0050875 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050875 GO:1902626 biolink:BiologicalProcess assembly of large subunit precursor of preribosome The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome. go-plus.json 66S preribosome formation|66S preribosome assembly|preribosome, large subunit precursor formation http://purl.obolibrary.org/obo/GO_1902626 GO:0050876 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050876 GO:1902623 biolink:BiologicalProcess negative regulation of neutrophil migration Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration. go-plus.json down regulation of neutrophil migration|inhibition of neutrophil migration|down-regulation of neutrophil migration|downregulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902623 GO:2001248 biolink:BiologicalProcess regulation of ammonia assimilation cycle Any process that modulates the frequency, rate or extent of ammonia assimilation cycle. go-plus.json regulation of glutamate metabolic process via glutamine and ammonia|regulation of glutamate metabolism via glutamine and ammonia http://purl.obolibrary.org/obo/GO_2001248 NCBITaxon:1639 biolink:OrganismalEntity Listeria monocytogenes go-plus.json Bacterium monocytogenes|Corynebacterium parvulum|Corynebacterium infantisepticum|Bacterium monocytogenes hominis|Listerella hepatolytica|Erysipelothrix monocytogenes http://purl.obolibrary.org/obo/NCBITaxon_1639 GO:1902624 biolink:BiologicalProcess positive regulation of neutrophil migration Any process that activates or increases the frequency, rate or extent of neutrophil migration. go-plus.json upregulation of neutrophil migration|up-regulation of neutrophil migration|activation of neutrophil migration|up regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902624 GO:2001249 biolink:BiologicalProcess negative regulation of ammonia assimilation cycle Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle. go-plus.json negative regulation of glutamate metabolic process via glutamine and ammonia|negative regulation of glutamate metabolism via glutamine and ammonia http://purl.obolibrary.org/obo/GO_2001249 GO:0050879 biolink:BiologicalProcess multicellular organismal movement Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0050879 goslim_pir GO:1902621 biolink:BiologicalProcess actomyosin contractile ring disassembly The disaggregation of an actomyosin contractile ring into its constituent components. go-plus.json CAR disassembly|constriction ring disassembly|contractile actomyosin ring disassembly|cytokinetic ring disassembly|actomyosin ring disassembly http://purl.obolibrary.org/obo/GO_1902621 CHEBI:86363 biolink:ChemicalSubstance 2-dehydro-L-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86363 GO:1902622 biolink:BiologicalProcess regulation of neutrophil migration Any process that modulates the frequency, rate or extent of neutrophil migration. go-plus.json http://purl.obolibrary.org/obo/GO_1902622 GO:1902620 biolink:BiologicalProcess positive regulation of microtubule minus-end binding Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding. go-plus.json upregulation of microtubule minus-end binding|up regulation of microtubule minus-end binding|activation of microtubule minus-end binding|up-regulation of microtubule minus-end binding http://purl.obolibrary.org/obo/GO_1902620 NCBITaxon:1637 biolink:OrganismalEntity Listeria go-plus.json Listerella http://purl.obolibrary.org/obo/NCBITaxon_1637 GO:0035298 biolink:BiologicalProcess regulation of Malpighian tubule size Ensuring that a Malpighian tubule is the correct length and diameter. go-plus.json http://purl.obolibrary.org/obo/GO_0035298 GO:2001240 biolink:BiologicalProcess negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. go-plus.json negative regulation of extrinsic apoptosis in absence of ligand|negative regulation of dependence receptor signaling pathway|negative regulation of extrinsic apoptotic signalling pathway in absence of ligand http://purl.obolibrary.org/obo/GO_2001240 GO:0035299 biolink:MolecularActivity inositol pentakisphosphate 2-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+). RHEA:20313|MetaCyc:RXN-7163|KEGG_REACTION:R05202|Reactome:R-HSA-1855179|Reactome:R-HSA-1855176|EC:2.7.1.158 go-plus.json inositol polyphosphate kinase activity|inositol hexakisphosphate synthase|Ins(1,3,4,5,6)P5 2-kinase activity|inositol-pentakisphosphate 2-kinase activity|Ipk1p|Gsl1p|IP5 2-kinase activity|inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity|ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0035299 GO:2001241 biolink:BiologicalProcess positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. go-plus.json positive regulation of extrinsic apoptosis in absence of ligand|positive regulation of dependence receptor signaling pathway|positive regulation of extrinsic apoptotic signalling pathway in absence of ligand http://purl.obolibrary.org/obo/GO_2001241 GO:2001242 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway. go-plus.json regulation of intrinsic apoptotic pathway|regulation of mitochondrial-mediated apoptotic pathway|regulation of intrinsic apoptotic signalling pathway|regulation of intrinsic apoptosis http://purl.obolibrary.org/obo/GO_2001242 GO:2001243 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway. go-plus.json negative regulation of mitochondrial-mediated apoptotic pathway|negative regulation of intrinsic apoptosis|negative regulation of intrinsic apoptotic signalling pathway|negative regulation of intrinsic apoptotic pathway http://purl.obolibrary.org/obo/GO_2001243 GO:0098819 biolink:BiologicalProcess depolarization of postsynaptic membrane A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold. go-plus.json http://purl.obolibrary.org/obo/GO_0098819 GO:2001244 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway. go-plus.json positive regulation of intrinsic apoptosis|positive regulation of mitochondrial-mediated apoptotic pathway|positive regulation of intrinsic apoptotic pathway|positive regulation of intrinsic apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001244 GO:2001245 biolink:BiologicalProcess regulation of phosphatidylcholine biosynthetic process Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process. go-plus.json regulation of phosphatidylcholine biosynthesis|regulation of phosphatidylcholine anabolism|regulation of phosphatidylcholine synthesis|regulation of phosphatidylcholine formation http://purl.obolibrary.org/obo/GO_2001245 GO:2001246 biolink:BiologicalProcess negative regulation of phosphatidylcholine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process. go-plus.json negative regulation of phosphatidylcholine biosynthesis|negative regulation of phosphatidylcholine synthesis|negative regulation of phosphatidylcholine formation|negative regulation of phosphatidylcholine anabolism http://purl.obolibrary.org/obo/GO_2001246 GO:0098817 biolink:BiologicalProcess evoked excitatory postsynaptic potential A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0098817 GO:2001247 biolink:BiologicalProcess positive regulation of phosphatidylcholine biosynthetic process Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process. go-plus.json positive regulation of phosphatidylcholine formation|positive regulation of phosphatidylcholine biosynthesis|positive regulation of phosphatidylcholine anabolism|positive regulation of phosphatidylcholine synthesis http://purl.obolibrary.org/obo/GO_2001247 GO:0098818 biolink:BiologicalProcess hyperpolarization of postsynaptic membrane A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold. go-plus.json http://purl.obolibrary.org/obo/GO_0098818 GO:0035290 biolink:BiologicalProcess trunk segmentation Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. go-plus.json http://purl.obolibrary.org/obo/GO_0035290 GO:0098815 biolink:BiologicalProcess modulation of excitatory postsynaptic potential Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. go-plus.json http://purl.obolibrary.org/obo/GO_0098815 GO:0035291 biolink:BiologicalProcess specification of segmental identity, intercalary segment The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0035291 GO:0098816 biolink:BiologicalProcess mini excitatory postsynaptic potential A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0098816 GO:0035292 biolink:BiologicalProcess specification of segmental identity, trunk The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0035292 GO:0098813 biolink:BiologicalProcess nuclear chromosome segregation The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. go-plus.json http://purl.obolibrary.org/obo/GO_0098813 GO:0035293 biolink:BiologicalProcess chitin-based larval cuticle pattern formation The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0035293 GO:0098814 biolink:BiologicalProcess spontaneous synaptic transmission The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential. go-plus.json basal synaptic transmission http://purl.obolibrary.org/obo/GO_0098814 goslim_synapse GO:0098811 biolink:MolecularActivity obsolete transcriptional repressor activity, RNA polymerase II activating transcription factor binding OBSOLETE. Binding to an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. go-plus.json RNA polymerase II activating transcription factor binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription repressor activity|RNA polymerase II activating transcription factor binding transcription repressor activity http://purl.obolibrary.org/obo/GO_0098811 GO:0035294 biolink:BiologicalProcess determination of wing disc primordium Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc. go-plus.json http://purl.obolibrary.org/obo/GO_0035294 GO:0050870 biolink:BiologicalProcess positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell activation. go-plus.json positive regulation of T lymphocyte activation|up regulation of T cell activation|activation of T cell activation|stimulation of T cell activation|positive regulation of T-lymphocyte activation|up-regulation of T cell activation|positive regulation of T-cell activation|upregulation of T cell activation http://purl.obolibrary.org/obo/GO_0050870 GO:0035295 biolink:BiologicalProcess tube development The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. go-plus.json http://purl.obolibrary.org/obo/GO_0035295 GO:0098812 biolink:BiologicalProcess nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a rRNA, occurring as part of the process of polyadenylation-dependent rRNA catabolism in the nucleus. go-plus.json nuclear rRNA polyadenylation involved in poly(A)-dependent rRNA catabolic process|nuclear rRNA polyadenylation during polyadenylation-dependent rRNA catabolic process http://purl.obolibrary.org/obo/GO_0098812 GO:0035296 biolink:BiologicalProcess regulation of tube diameter Any process that modulates the diameter of a tube. go-plus.json http://purl.obolibrary.org/obo/GO_0035296 GO:0035297 biolink:BiologicalProcess regulation of Malpighian tubule diameter Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells. go-plus.json http://purl.obolibrary.org/obo/GO_0035297 GO:0098810 biolink:BiologicalProcess neurotransmitter reuptake The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0098810 goslim_synapse GO:0050884 biolink:BiologicalProcess neuromuscular process controlling posture Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. go-plus.json regulation of posture http://purl.obolibrary.org/obo/GO_0050884 GO:0050885 biolink:BiologicalProcess neuromuscular process controlling balance Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. go-plus.json regulation of balance http://purl.obolibrary.org/obo/GO_0050885 GO:0050882 biolink:BiologicalProcess voluntary musculoskeletal movement The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will. go-plus.json http://purl.obolibrary.org/obo/GO_0050882 GO:0050883 biolink:BiologicalProcess musculoskeletal movement, spinal reflex action Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0050883 GO:1902638 biolink:BiologicalProcess neural crest cell differentiation involved in parathyroid gland development Any neural crest cell differentiation that is involved in parathyroid gland development. go-plus.json http://purl.obolibrary.org/obo/GO_1902638 GO:0050888 biolink:BiologicalProcess determination of stimulus location The determination of where on the body surface, within the body or in the environment a stimulus originates. go-plus.json http://purl.obolibrary.org/obo/GO_0050888 GO:1902639 biolink:BiologicalProcess propan-2-ol metabolic process The chemical reactions and pathways involving propan-2-ol. go-plus.json Isopropyl alcohol metabolic process|propan-2-ol metabolism|Isopropanol metabolic process http://purl.obolibrary.org/obo/GO_1902639 GO:0050889 biolink:BiologicalProcess determination of stimulus intensity The determination of the perceived strength of a sensory stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0050889 GO:1902636 biolink:CellularComponent kinociliary basal body A ciliary basal body that is part of a kinocilium. go-plus.json cilial basal body of kinocilium|kinocilium basal body|microtubule basal body of kinocilium|kinocilium ciliary basal body|cilium basal body of kinocilium|kinocilial basal body|ciliary basal body of kinocilium http://purl.obolibrary.org/obo/GO_1902636 GO:0050886 biolink:BiologicalProcess endocrine process The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. go-plus.json endocrine physiological process|endocrine physiology http://purl.obolibrary.org/obo/GO_0050886 goslim_pir CHEBI:86392 biolink:ChemicalSubstance 4-guanidinobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86392 GO:1902637 biolink:BiologicalProcess neural crest cell differentiation involved in thymus development Any neural crest cell differentiation that is involved in thymus development. go-plus.json http://purl.obolibrary.org/obo/GO_1902637 GO:0050887 biolink:BiologicalProcess determination of sensory modality The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain. go-plus.json http://purl.obolibrary.org/obo/GO_0050887 GO:1902634 biolink:BiologicalProcess 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. go-plus.json 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism http://purl.obolibrary.org/obo/GO_1902634 GO:2001259 biolink:BiologicalProcess positive regulation of cation channel activity Any process that activates or increases the frequency, rate or extent of cation channel activity. go-plus.json positive regulation of nonselective cation channel activity|positive regulation of cation diffusion facilitator activity http://purl.obolibrary.org/obo/GO_2001259 CHEBI:86394 biolink:ChemicalSubstance 5-aminopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86394 GO:1902635 biolink:BiologicalProcess 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. go-plus.json 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis http://purl.obolibrary.org/obo/GO_1902635 GO:1902632 biolink:BiologicalProcess positive regulation of membrane hyperpolarization Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization. go-plus.json upregulation of membrane hyperpolarization|up-regulation of membrane hyperpolarization|activation of membrane hyperpolarization|up regulation of membrane hyperpolarization http://purl.obolibrary.org/obo/GO_1902632 GO:1902633 biolink:BiologicalProcess 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. go-plus.json 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolism http://purl.obolibrary.org/obo/GO_1902633 GO:1902630 biolink:BiologicalProcess regulation of membrane hyperpolarization Any process that modulates the frequency, rate or extent of membrane hyperpolarization. go-plus.json http://purl.obolibrary.org/obo/GO_1902630 GO:1902631 biolink:BiologicalProcess negative regulation of membrane hyperpolarization Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization. go-plus.json downregulation of membrane hyperpolarization|down regulation of membrane hyperpolarization|inhibition of membrane hyperpolarization|down-regulation of membrane hyperpolarization http://purl.obolibrary.org/obo/GO_1902631 CHEBI:86399 biolink:ChemicalSubstance (4R,6R)-hydroxy-2,2,6-trimethylcyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_86399 chebi_ph7_3 GO:2001251 biolink:BiologicalProcess negative regulation of chromosome organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. go-plus.json negative regulation of chromosome organization and biogenesis|negative regulation of chromosome organisation|negative regulation of nuclear genome maintenance|negative regulation of maintenance of genome integrity http://purl.obolibrary.org/obo/GO_2001251 GO:0060210 biolink:BiologicalProcess metestrus The estrous cycle phase in which there is subsiding follicular function. go-plus.json http://purl.obolibrary.org/obo/GO_0060210 gocheck_do_not_annotate GO:0035287 biolink:BiologicalProcess head segmentation Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial). go-plus.json http://purl.obolibrary.org/obo/GO_0035287 GO:2001252 biolink:BiologicalProcess positive regulation of chromosome organization Any process that activates or increases the frequency, rate or extent of chromosome organization. go-plus.json positive regulation of chromosome organisation|positive regulation of chromosome organization and biogenesis|positive regulation of maintenance of genome integrity|positive regulation of nuclear genome maintenance http://purl.obolibrary.org/obo/GO_2001252 GO:0035288 biolink:BiologicalProcess anterior head segmentation Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments. go-plus.json procephalic segmentation http://purl.obolibrary.org/obo/GO_0035288 GO:0060211 biolink:BiologicalProcess regulation of nuclear-transcribed mRNA poly(A) tail shortening Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. go-plus.json regulation of mRNA deadenylation|regulation of nuclear mRNA poly(A) tail shortening|regulation of 3' to 5' mRNA deadenylation http://purl.obolibrary.org/obo/GO_0060211 GO:0035289 biolink:BiologicalProcess posterior head segmentation Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains. go-plus.json gnathal segmentation http://purl.obolibrary.org/obo/GO_0035289 GO:2001253 biolink:BiologicalProcess regulation of histone H3-K36 trimethylation Any process that modulates the frequency, rate or extent of histone H3-K36 trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_2001253 GO:0060212 biolink:BiologicalProcess negative regulation of nuclear-transcribed mRNA poly(A) tail shortening Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. go-plus.json negative regulation of nuclear mRNA poly(A) tail shortening|negative regulation of mRNA deadenylation|negative regulation of 3' to 5' mRNA deadenylation http://purl.obolibrary.org/obo/GO_0060212 GO:2001254 biolink:BiologicalProcess negative regulation of histone H3-K36 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K36 trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_2001254 GO:0060213 biolink:BiologicalProcess positive regulation of nuclear-transcribed mRNA poly(A) tail shortening Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. go-plus.json positive regulation of nuclear mRNA poly(A) tail shortening|positive regulation of 3' to 5' mRNA deadenylation|positive regulation of mRNA deadenylation http://purl.obolibrary.org/obo/GO_0060213 GO:2001255 biolink:BiologicalProcess positive regulation of histone H3-K36 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_2001255 GO:0060214 biolink:BiologicalProcess endocardium formation Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go-plus.json http://purl.obolibrary.org/obo/GO_0060214 GO:2001256 biolink:BiologicalProcess regulation of store-operated calcium entry Any process that modulates the frequency, rate or extent of store-operated calcium entry. go-plus.json regulation of calcium ion import|regulation of store-operated calcium import|regulation of capacitative calcium entry|regulation of SOCE http://purl.obolibrary.org/obo/GO_2001256 GO:0060215 biolink:BiologicalProcess primitive hemopoiesis A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells. go-plus.json primitive haematopoiesis|primitive hematopoiesis|primitive haemopoiesis http://purl.obolibrary.org/obo/GO_0060215 GO:2001257 biolink:BiologicalProcess regulation of cation channel activity Any process that modulates the frequency, rate or extent of cation channel activity. go-plus.json regulation of nonselective cation channel activity|regulation of cation diffusion facilitator activity http://purl.obolibrary.org/obo/GO_2001257 GO:0060216 biolink:BiologicalProcess definitive hemopoiesis A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood. go-plus.json definitive haematopoiesis|definitive hematopoiesis|definitive haemopoiesis http://purl.obolibrary.org/obo/GO_0060216 GO:2001258 biolink:BiologicalProcess negative regulation of cation channel activity Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity. go-plus.json negative regulation of cation diffusion facilitator activity|negative regulation of nonselective cation channel activity http://purl.obolibrary.org/obo/GO_2001258 GO:0060217 biolink:BiologicalProcess hemangioblast cell differentiation The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages. go-plus.json http://purl.obolibrary.org/obo/GO_0060217 GO:0060218 biolink:BiologicalProcess hematopoietic stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. go-plus.json haemopoietic stem cell differentiation|haematopoietic stem cell differentiation|hemopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_0060218 GO:0060219 biolink:BiologicalProcess camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0060219 GO:0035280 biolink:BiologicalProcess miRNA loading onto RISC involved in gene silencing by miRNA The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC). go-plus.json miRISC assembly|gene silencing by miRNA, miRNA loading onto RISC|miRNA-mediated gene silencing, miRNA loading onto RISC|microRNA loading onto RISC involved in gene silencing by microRNA http://purl.obolibrary.org/obo/GO_0035280 GO:0035281 biolink:BiologicalProcess pre-miRNA export from nucleus Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product. go-plus.json pre-microRNA-nucleus export|pre-microRNA transport from nucleus to cytoplasm|pre-microRNA export from cell nucleus|pre-microRNA export out of nucleus|pre-microRNA export from nucleus http://purl.obolibrary.org/obo/GO_0035281 GO:0035282 biolink:BiologicalProcess segmentation The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. Wikipedia:Segmentation_(biology) go-plus.json http://purl.obolibrary.org/obo/GO_0035282 GO:0035283 biolink:BiologicalProcess central nervous system segmentation Division of the central nervous system into a series of semi-repetitive parts or segments. go-plus.json http://purl.obolibrary.org/obo/GO_0035283 GO:0050880 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050880 GO:0050881 biolink:BiologicalProcess musculoskeletal movement The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. go-plus.json http://purl.obolibrary.org/obo/GO_0050881 GO:0035284 biolink:BiologicalProcess brain segmentation Division of the brain into a series of semi-repetitive parts or segments. go-plus.json http://purl.obolibrary.org/obo/GO_0035284 GO:0035285 biolink:BiologicalProcess appendage segmentation Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented. go-plus.json http://purl.obolibrary.org/obo/GO_0035285 GO:0035286 biolink:BiologicalProcess obsolete leg segmentation OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint. go-plus.json leg segmentation http://purl.obolibrary.org/obo/GO_0035286 GO:2001250 biolink:BiologicalProcess positive regulation of ammonia assimilation cycle Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle. go-plus.json positive regulation of glutamate metabolic process via glutamine and ammonia|positive regulation of glutamate metabolism via glutamine and ammonia http://purl.obolibrary.org/obo/GO_2001250 GO:0050895 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0050895 GO:0050896 biolink:BiologicalProcess response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. go-plus.json physiological response to stimulus http://purl.obolibrary.org/obo/GO_0050896 goslim_mouse|goslim_agr|gocheck_do_not_manually_annotate|goslim_pir|goslim_flybase_ribbon GO:0050893 biolink:BiologicalProcess sensory processing Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect. go-plus.json http://purl.obolibrary.org/obo/GO_0050893 GO:0050894 biolink:BiologicalProcess determination of affect Any process in which an emotional response is associated with a particular sensory stimulation. go-plus.json http://purl.obolibrary.org/obo/GO_0050894 GO:0050899 biolink:BiologicalProcess nitrile catabolic process The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom. go-plus.json nitrile degradation|nitrile breakdown|nitrile catabolism http://purl.obolibrary.org/obo/GO_0050899 GO:1902649 biolink:BiologicalProcess regulation of histone H2A-H2B dimer displacement Any process that modulates the frequency, rate or extent of histone H2A-H2B dimer displacement. go-plus.json http://purl.obolibrary.org/obo/GO_1902649 GO:1902647 biolink:BiologicalProcess negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. go-plus.json down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis http://purl.obolibrary.org/obo/GO_1902647 CHEBI:86381 biolink:ChemicalSubstance 5beta-dihydrocorticosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_86381 chebi_ph7_3 GO:0050897 biolink:MolecularActivity cobalt ion binding Binding to a cobalt ion (Co). go-plus.json Co ion binding|cobalt binding http://purl.obolibrary.org/obo/GO_0050897 GO:1902648 biolink:BiologicalProcess positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. go-plus.json upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis http://purl.obolibrary.org/obo/GO_1902648 CHEBI:86382 biolink:ChemicalSubstance alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86382 GO:0050898 biolink:BiologicalProcess nitrile metabolic process The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile. go-plus.json nitrile metabolism http://purl.obolibrary.org/obo/GO_0050898 GO:1902645 biolink:BiologicalProcess tertiary alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of tertiary alcohol. go-plus.json tertiary alcohol anabolism|tertiary alcohol synthesis|tertiary alcohol formation|tertiary alcohol biosynthesis http://purl.obolibrary.org/obo/GO_1902645 CHEBI:86384 biolink:ChemicalSubstance 5beta-dihydrodeoxycorticosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_86384 chebi_ph7_3 GO:1902646 biolink:BiologicalProcess regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. go-plus.json regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism http://purl.obolibrary.org/obo/GO_1902646 GO:1902643 biolink:BiologicalProcess positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process. go-plus.json up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism http://purl.obolibrary.org/obo/GO_1902643 CHEBI:86386 biolink:ChemicalSubstance 3-mercaptopropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_86386 chebi_ph7_3 GO:1902644 biolink:BiologicalProcess tertiary alcohol metabolic process The chemical reactions and pathways involving tertiary alcohol. go-plus.json tertiary alcohol metabolism http://purl.obolibrary.org/obo/GO_1902644 GO:1902641 biolink:BiologicalProcess regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process. go-plus.json regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown http://purl.obolibrary.org/obo/GO_1902641 GO:1902642 biolink:BiologicalProcess negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process. go-plus.json down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation http://purl.obolibrary.org/obo/GO_1902642 CHEBI:86389 biolink:ChemicalSubstance 5beta-dihydroaldosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_86389 chebi_ph7_3 GO:1902640 biolink:BiologicalProcess propan-2-ol biosynthetic process The chemical reactions and pathways resulting in the formation of propan-2-ol. go-plus.json propan-2-ol formation|propan-2-ol biosynthesis|Isopropyl alcohol biosynthetic process|propan-2-ol anabolism|Isopropanol biosynthetic process|propan-2-ol synthesis http://purl.obolibrary.org/obo/GO_1902640 GO:2001262 biolink:BiologicalProcess positive regulation of semaphorin-plexin signaling pathway Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway. go-plus.json positive regulation of semaphorin-plexin signalling pathway http://purl.obolibrary.org/obo/GO_2001262 GO:0035276 biolink:MolecularActivity ethanol binding Binding to ethanol, CH(3)-CH(2)-OH. go-plus.json http://purl.obolibrary.org/obo/GO_0035276 GO:0060200 biolink:CellularComponent clathrin-sculpted acetylcholine transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine. go-plus.json clathrin sculpted acetylcholine transport vesicle|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle http://purl.obolibrary.org/obo/GO_0060200 GO:2001263 biolink:BiologicalProcess regulation of C-C chemokine binding Any process that modulates the frequency, rate or extent of C-C chemokine binding. go-plus.json http://purl.obolibrary.org/obo/GO_2001263 GO:0035277 biolink:BiologicalProcess spiracle morphogenesis, open tracheal system The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk. go-plus.json spiracle morphogenesis http://purl.obolibrary.org/obo/GO_0035277 GO:0060201 biolink:CellularComponent clathrin-sculpted acetylcholine transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle. go-plus.json clathrin sculpted acetylcholine transport vesicle membrane|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle membrane http://purl.obolibrary.org/obo/GO_0060201 GO:0035278 biolink:BiologicalProcess miRNA mediated inhibition of translation The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs. go-plus.json inhibition of translation involved in gene silencing by miRNA|gene silencing by miRNA, negative regulation of translation|miRNA-mediated gene silencing, negative regulation of translation|down regulation of translation involved in gene silencing by miRNA|downregulation of translation involved in gene silencing by miRNA|negative regulation of translation involved in gene silencing by microRNA|down-regulation of translation involved in gene silencing by miRNA http://purl.obolibrary.org/obo/GO_0035278 GO:2001264 biolink:BiologicalProcess negative regulation of C-C chemokine binding Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding. go-plus.json http://purl.obolibrary.org/obo/GO_2001264 GO:2001265 biolink:BiologicalProcess positive regulation of C-C chemokine binding Any process that activates or increases the frequency, rate or extent of C-C chemokine binding. go-plus.json http://purl.obolibrary.org/obo/GO_2001265 GO:0060202 biolink:CellularComponent clathrin-sculpted acetylcholine transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle. go-plus.json clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle lumen|clathrin sculpted acetylcholine transport vesicle lumen http://purl.obolibrary.org/obo/GO_0060202 GO:0035279 biolink:BiologicalProcess mRNA cleavage involved in gene silencing by miRNA The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. go-plus.json gene silencing by miRNA, mRNA cleavage|miRNA-mediated gene silencing, mRNA cleavage|mRNA cleavage involved in gene silencing by microRNA http://purl.obolibrary.org/obo/GO_0035279 GO:2001266 biolink:BiologicalProcess Roundabout signaling pathway involved in axon guidance Any Roundabout signaling pathway that is involved in axon guidance. go-plus.json Roundabout signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon pathfinding|Roundabout signalling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon pathfinding|ROBO signaling pathway involved in axon guidance|ROBO signaling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon guidance|ROBO signaling pathway involved in axon growth cone guidance|ROBO/SLIT signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon guidance|Roundabout signalling pathway involved in axon growth cone guidance|ROBO signaling pathway involved in axon chemotaxis|ROBO/SLIT signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon chemotaxis http://purl.obolibrary.org/obo/GO_2001266 GO:0060203 biolink:CellularComponent clathrin-sculpted glutamate transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle. go-plus.json clathrin sculpted glutamate transport vesicle membrane|clathrin sculpted glutamate constitutive secretory pathway transport vesicle membrane http://purl.obolibrary.org/obo/GO_0060203 GO:0060204 biolink:CellularComponent clathrin-sculpted glutamate transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle. go-plus.json clathrin sculpted glutamate transport vesicle lumen|clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen http://purl.obolibrary.org/obo/GO_0060204 GO:2001267 biolink:BiologicalProcess regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. go-plus.json regulation of initiator caspase activity|regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_2001267 GO:2001268 biolink:BiologicalProcess negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. go-plus.json negative regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|negative regulation of initiator caspase activity http://purl.obolibrary.org/obo/GO_2001268 GO:0060205 biolink:CellularComponent cytoplasmic vesicle lumen The volume enclosed by a cytoplasmic vesicle. go-plus.json cytoplasmic membrane-enclosed vesicle lumen|cytoplasmic membrane-bounded vesicle lumen http://purl.obolibrary.org/obo/GO_0060205 GO:0060206 biolink:BiologicalProcess estrous cycle phase The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur. go-plus.json http://purl.obolibrary.org/obo/GO_0060206 gocheck_do_not_annotate GO:2001269 biolink:BiologicalProcess positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. go-plus.json positive regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|positive regulation of initiator caspase activity http://purl.obolibrary.org/obo/GO_2001269 GO:0060207 biolink:BiologicalProcess diestrus The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum. go-plus.json http://purl.obolibrary.org/obo/GO_0060207 gocheck_do_not_annotate GO:0060208 biolink:BiologicalProcess proestrus The estrous cycle phase in which there is heightened follicular activity. go-plus.json http://purl.obolibrary.org/obo/GO_0060208 gocheck_do_not_annotate GO:0060209 biolink:BiologicalProcess estrus The estrous cycle phase in which a female is sexually receptive. go-plus.json oestrus http://purl.obolibrary.org/obo/GO_0060209 gocheck_do_not_annotate GO:0035270 biolink:BiologicalProcess endocrine system development Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. go-plus.json http://purl.obolibrary.org/obo/GO_0035270 GO:0035271 biolink:BiologicalProcess ring gland development Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0035271 GO:0050891 biolink:BiologicalProcess multicellular organismal water homeostasis Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism. go-plus.json body fluid osmoregulation http://purl.obolibrary.org/obo/GO_0050891 GO:0035272 biolink:BiologicalProcess exocrine system development Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. go-plus.json http://purl.obolibrary.org/obo/GO_0035272 GO:0050892 biolink:BiologicalProcess intestinal absorption Any process in which nutrients are taken up from the contents of the intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0050892 GO:0035273 biolink:MolecularActivity phthalate binding Binding to a phthalate, any ester or salt of phthalic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0035273 goslim_pir GO:0035274 biolink:MolecularActivity diphenyl phthalate binding Binding to diphenyl phthalate, C(20)H(14)O(4). go-plus.json DPP binding http://purl.obolibrary.org/obo/GO_0035274 GO:2001260 biolink:BiologicalProcess regulation of semaphorin-plexin signaling pathway Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway. go-plus.json regulation of semaphorin-plexin signalling pathway http://purl.obolibrary.org/obo/GO_2001260 GO:0035275 biolink:MolecularActivity dibutyl phthalate binding Binding to dibutyl phthalate, C(16)H(22)O(4). go-plus.json DBP binding|phthalic acid dibutyl ester binding http://purl.obolibrary.org/obo/GO_0035275 GO:0050890 biolink:BiologicalProcess cognition The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. Wikipedia:Cognition go-plus.json http://purl.obolibrary.org/obo/GO_0050890 goslim_drosophila GO:2001261 biolink:BiologicalProcess negative regulation of semaphorin-plexin signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway. go-plus.json negative regulation of semaphorin-plexin signalling pathway http://purl.obolibrary.org/obo/GO_2001261 CHEBI:76922 biolink:ChemicalSubstance argemonine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76922 chebi_ph7_3 NCBITaxon:1423 biolink:OrganismalEntity Bacillus subtilis go-plus.json Vibrio subtilis|Bacillus uniflagellatus|Bacillus mesentericus|Bacillus subtilis/Bacillus globigii|Bacillus natto http://purl.obolibrary.org/obo/NCBITaxon_1423 CHEBI:76921 biolink:ChemicalSubstance pavine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76921 chebi_ph7_3 CHEBI:27995 biolink:ChemicalSubstance 3-methylbenzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27995 chebi_ph7_3 CHEBI:27996 biolink:ChemicalSubstance (R)-4-hydroxymandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27996 chebi_ph7_3 CHEBI:76924 biolink:ChemicalSubstance plant metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76924 CHEBI:27997 biolink:ChemicalSubstance elaidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27997 CHEBI:27998 biolink:ChemicalSubstance tungsten go-plus.json http://purl.obolibrary.org/obo/CHEBI_27998 chebi_ph7_3 CHEBI:27991 biolink:ChemicalSubstance benzonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_27991 chebi_ph7_3 CHEBI:76928 biolink:ChemicalSubstance 2,3-saturated fatty acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76928 chebi_ph7_3 CHEBI:27993 biolink:ChemicalSubstance 1,2-di-O-sinapoyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27993 chebi_ph7_3 CHEBI:27994 biolink:ChemicalSubstance luteolin 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27994 CHEBI:76929 biolink:ChemicalSubstance 2,3-saturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76929 CHEBI:37318 biolink:ChemicalSubstance 2-oxopent-4-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37318 CHEBI:37319 biolink:ChemicalSubstance 2-hydroxypenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37319 chebi_ph7_3 CHEBI:37316 biolink:ChemicalSubstance (E,E)-piperic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37316 CHEBI:13346 biolink:ChemicalSubstance Glu-tRNA(Glx) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13346 UBERON:0000344 biolink:AnatomicalEntity mucosa A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP] go-plus.json organ mucosa|mucosa of organ part|mucosal region|mucosa of organ|tunica mucosa|mucous membrane|region of mucosa http://purl.obolibrary.org/obo/UBERON_0000344 CHEBI:76933 biolink:ChemicalSubstance 3,18-dihydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76933 CHEBI:76934 biolink:ChemicalSubstance 3,12-dihydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76934 CHEBI:76931 biolink:ChemicalSubstance Ac-Asp-Glu(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76931 chebi_ph7_3 CHEBI:76932 biolink:ChemicalSubstance pathway inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76932 UBERON:0000325 biolink:AnatomicalEntity gastric gland The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000325 CHEBI:76937 biolink:ChemicalSubstance 11-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76937 UBERON:0000326 biolink:AnatomicalEntity pancreatic juice Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. go-plus.json pancreatic secretion|pancreatic fluid|succus pancreaticus http://purl.obolibrary.org/obo/UBERON_0000326 CHEBI:76938 biolink:ChemicalSubstance EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76938 CHEBI:76935 biolink:ChemicalSubstance Ac-Asp-Glu-Glu(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76935 chebi_ph7_3 UBERON:0000328 biolink:AnatomicalEntity gut wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). go-plus.json wall of digestive tract|wall of gut|wall of alimentary tract|digestive tract wall http://purl.obolibrary.org/obo/UBERON_0000328 CHEBI:76939 biolink:ChemicalSubstance EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76939 CHEBI:37325 biolink:ChemicalSubstance alloxazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37325 chebi_ph7_3 CHEBI:37326 biolink:ChemicalSubstance benzo[g]pteridine-2,4-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_37326 CHEBI:37323 biolink:ChemicalSubstance 7,8-dimethylisoalloxazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37323 CHEBI:37324 biolink:ChemicalSubstance 7,8-dimethylbenzo[g]pteridine-2,4-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_37324 CHEBI:13332 biolink:ChemicalSubstance GDP-beta-L-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_13332 CHEBI:37329 biolink:ChemicalSubstance phosphatidylinositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37329 CHEBI:37327 biolink:ChemicalSubstance isoalloxazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37327 CHEBI:37328 biolink:ChemicalSubstance phosphatidylinositol bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37328 UBERON:0000332 biolink:AnatomicalEntity yellow bone marrow bone marrow in which the fat cells predominate in the meshes of the reticular network. go-plus.json medulla ossium flava|fat marrow|yellow marrow http://purl.obolibrary.org/obo/UBERON_0000332 UBERON:0000333 biolink:AnatomicalEntity intestinal gland A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]. go-plus.json bowel mucous membrane gland|glandulae intestinales|gland of mucosa of intestine|gland of intestine organ mucosa|bowel mucosa gland|gland of mucous membrane of bowel|intestine mucosa of organ gland|organ mucosa of intestine gland|gland of intestinal mucosa|gland of mucosa of organ of bowel|intestine mucous membrane gland|gland of bowel mucosa of organ|gland of organ mucosa of bowel|gland of bowel organ mucosa|intestine organ mucosa gland|gland of mucous membrane of intestine|glandula intestinalis|mucous membrane of bowel gland|mucosa of bowel gland|gland of bowel mucous membrane|gland of mucosa of organ of intestine|gland of organ mucosa of intestine|gland of intestine mucosa|mucosa of organ of bowel gland|gland of intestine mucosa of organ|bowel organ mucosa gland|mucous membrane of intestine gland|mucosa of intestine gland|gland of intestine mucous membrane|intestinal mucosa gland|mucosa of organ of intestine gland|gland of bowel mucosa|intestine mucosa gland|gland of mucosa of bowel|bowel mucosa of organ gland|organ mucosa of bowel gland http://purl.obolibrary.org/obo/UBERON_0000333 CHEBI:37322 biolink:ChemicalSubstance penta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37322 chebi_ph7_3 CHEBI:76930 biolink:ChemicalSubstance omega-hydroxytetracosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76930 CHEBI:76944 biolink:ChemicalSubstance 13-epi-manool go-plus.json http://purl.obolibrary.org/obo/CHEBI_76944 chebi_ph7_3 CHEBI:27977 biolink:ChemicalSubstance erythronolide B go-plus.json http://purl.obolibrary.org/obo/CHEBI_27977 chebi_ph7_3 CHEBI:76945 biolink:ChemicalSubstance manool go-plus.json http://purl.obolibrary.org/obo/CHEBI_76945 chebi_ph7_3 CHEBI:27978 biolink:ChemicalSubstance 3,4-dihydroxyphenylacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27978 chebi_ph7_3 CHEBI:76942 biolink:ChemicalSubstance beta-citrylglutamate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76942 chebi_ph7_3 CHEBI:27979 biolink:ChemicalSubstance all-cis-icosa-8,11,14-trienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27979 CHEBI:76943 biolink:ChemicalSubstance (+)-copalol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76943 chebi_ph7_3 UBERON:0000314 biolink:AnatomicalEntity cecum mucosa A mucosa that is part of a cecum [Automatically generated definition]. go-plus.json mucosa of intestinum crassum caecum|mucosa of organ of cecum|mucosa of organ of intestinum crassum caecum|mucosa of organ of caecum|mucosa of caecum|cecum mucosa of organ|organ mucosa of cecum|mucous membrane of caecum|caecum organ mucosa|organ mucosa of intestinum crassum caecum|intestinum crassum caecum mucosa of organ|intestinum crassum caecum organ mucosa|caecum mucosa of organ|cecum mucous membrane|cecum organ mucosa|intestinum crassum caecum mucous membrane|cecal mucosa|caecum mucous membrane|mucous membrane of cecum|organ mucosa of caecum|mucosa of cecum|caecum mucosa|intestinum crassum caecum mucosa|mucous membrane of intestinum crassum caecum http://purl.obolibrary.org/obo/UBERON_0000314 CHEBI:27973 biolink:ChemicalSubstance D-arabino-hex-3-ulose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27973 CHEBI:76948 biolink:ChemicalSubstance ent-manool go-plus.json http://purl.obolibrary.org/obo/CHEBI_76948 chebi_ph7_3 UBERON:0000315 biolink:AnatomicalEntity subarachnoid space The space between the arachnoid and pia mater. go-plus.json spatium leptomeningeum|subarachnoid cavity|spatium subarachnoideum|cavitas subarachnoidea|cavum subarachnoideale http://purl.obolibrary.org/obo/UBERON_0000315 CHEBI:27974 biolink:ChemicalSubstance estriol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27974 chebi_ph7_3 UBERON:0000316 biolink:AnatomicalEntity cervical mucus A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus. go-plus.json cervix mucus http://purl.obolibrary.org/obo/UBERON_0000316 CHEBI:27975 biolink:ChemicalSubstance L-glyceraldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27975 chebi_ph7_3 CHEBI:76946 biolink:ChemicalSubstance fungal metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76946 UBERON:0000317 biolink:AnatomicalEntity colonic mucosa Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells. go-plus.json colonic mucosa|colon mucosa|mucosa of large bowel|colon mucous membrane|colonic mucous membrane|large bowel mucosa|mucosa of colon http://purl.obolibrary.org/obo/UBERON_0000317 CHEBI:27976 biolink:ChemicalSubstance prop-2-ynal go-plus.json http://purl.obolibrary.org/obo/CHEBI_27976 chebi_ph7_3 CHEBI:27972 biolink:ChemicalSubstance 2-deoxy-D-gluc-5-ulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27972 UBERON:0000323 biolink:AnatomicalEntity late embryo An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. go-plus.json fetus|embryo late stage|embryo late growth stage http://purl.obolibrary.org/obo/UBERON_0000323 CHEBI:76941 biolink:ChemicalSubstance sphingoid 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76941 chebi_ph7_3 UBERON:0000320 biolink:AnatomicalEntity duodenal mucosa A mucosa that is part of a duodenum [Automatically generated definition]. go-plus.json duodenum mucosa|doudenal mucosa|mucosa of duodenum|mucous membrane of duodenum|duodenal mucous membrane http://purl.obolibrary.org/obo/UBERON_0000320 UBERON:0000307 biolink:AnatomicalEntity blastula Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. go-plus.json blastula embryo|blastosphere http://purl.obolibrary.org/obo/UBERON_0000307 CHEBI:76955 biolink:ChemicalSubstance 17(S),18(R)-EETeTr go-plus.json http://purl.obolibrary.org/obo/CHEBI_76955 CHEBI:27989 biolink:ChemicalSubstance cis-dodec-3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27989 CHEBI:76956 biolink:ChemicalSubstance Aspergillus metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76956 UBERON:0000309 biolink:AnatomicalEntity body wall The external portion of an animal body derived from ectoderm and mesoderm layers that encloses the body cavity. go-plus.json trunk wall|wall fo trunk|wall of trunk http://purl.obolibrary.org/obo/UBERON_0000309 CHEBI:76953 biolink:ChemicalSubstance 17(R),18(S)-EETeTr go-plus.json http://purl.obolibrary.org/obo/CHEBI_76953 CHEBI:76954 biolink:ChemicalSubstance (13S)-vitexifolin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_76954 chebi_ph7_3 CHEBI:76959 biolink:ChemicalSubstance 19-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_76959 UBERON:0000304 biolink:AnatomicalEntity tendon sheath A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath go-plus.json vagina tendinis|synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0000304 CHEBI:27986 biolink:ChemicalSubstance nitrosobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27986 chebi_ph7_3 NCBITaxon:84337 biolink:OrganismalEntity Diplostraca go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_84337 UBERON:0014950 biolink:AnatomicalEntity layer of developing cerebral cortex go-plus.json http://purl.obolibrary.org/obo/UBERON_0014950 CHEBI:62318 biolink:ChemicalSubstance D-lyxose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62318 UBERON:0000310 biolink:AnatomicalEntity breast The upper ventral region of the torso of an organism. go-plus.json mamma|mammary region|mammary part of chest http://purl.obolibrary.org/obo/UBERON_0000310 UBERON:0000313 biolink:AnatomicalEntity portion of cartilage tissue in tibia Cartilage pertaining to the tibia. go-plus.json tibial cartilage|cartilage of tibia http://purl.obolibrary.org/obo/UBERON_0000313 CHEBI:76952 biolink:ChemicalSubstance syn-copalol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76952 chebi_ph7_3 CHEBI:76950 biolink:ChemicalSubstance (-)-ent-copalol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76950 chebi_ph7_3 CHEBI:27955 biolink:ChemicalSubstance streptamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27955 CHEBI:76966 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z)-icosatetraenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76966 CHEBI:76967 biolink:ChemicalSubstance human xenobiotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76967 CHEBI:27956 biolink:ChemicalSubstance L-dehydroascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27956 CHEBI:76964 biolink:ChemicalSubstance Penicillium metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76964 CHEBI:27957 biolink:ChemicalSubstance hydroxyacetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27957 chebi_ph7_3 CHEBI:76965 biolink:ChemicalSubstance 20-oxoarachidonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76965 CHEBI:27958 biolink:ChemicalSubstance cocaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27958 CHEBI:27951 biolink:ChemicalSubstance (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27951 CHEBI:76968 biolink:ChemicalSubstance fungal xenobiotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76968 CHEBI:76969 biolink:ChemicalSubstance bacterial metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76969 PO:0000207 biolink:OntologyClass nectary epidermis A portion of shoot system epidermis (PO:0006035) that is part of a nectary (PO:0009035) . go-plus.json 蜜腺表皮 (Japanese, exact)|epidermis del nectario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000207 CHEBI:52915 biolink:ChemicalSubstance phosphatediyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_52915 CHEBI:62320 biolink:ChemicalSubstance L-lyxose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62320 GO:2001075 biolink:BiologicalProcess negative regulation of metanephric ureteric bud development Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development. go-plus.json http://purl.obolibrary.org/obo/GO_2001075 GO:2001076 biolink:BiologicalProcess positive regulation of metanephric ureteric bud development Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development. go-plus.json http://purl.obolibrary.org/obo/GO_2001076 GO:2001077 biolink:MolecularActivity (1->3),(1->4)-beta-glucan binding Binding to (1->3),(1->4)-beta-glucan. go-plus.json beta-(1->3),(1->4)-glucan binding|1->3,1->4-beta-glucan binding|beta-1->3,1->4-glucan binding|(1,3),(1,4)-beta-glucan binding|beta-1,3-1,4-glucan binding|beta-(1,3),(1,4)-glucan binding http://purl.obolibrary.org/obo/GO_2001077 GO:2001078 biolink:MolecularActivity (1->6)-beta-D-glucan binding Binding to (1->6)-beta-D-glucan. go-plus.json beta-(1,6)-D-glucan binding|beta-1,6-D-glucan binding|1,6-beta-D-glucan binding|(1,6)-beta-D-glucan binding|1->6-beta-D-glucan binding|beta-(1->6)-D-glucan binding|beta-1->6-D-glucan binding http://purl.obolibrary.org/obo/GO_2001078 UBERON:0000382 biolink:AnatomicalEntity apocrine sweat gland Apocrine sweat glands are sweat glands composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. The ducts of apocrine glands open into the canals of hair follicles. The stimulus for the secretion of apocrine sweat glands is adrenaline, which is a hormone carried in the blood[WP]. go-plus.json glandula sudorifera apocrina http://purl.obolibrary.org/obo/UBERON_0000382 CHEBI:62324 biolink:ChemicalSubstance D-mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62324 GO:2001079 biolink:MolecularActivity beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding Binding to beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc. go-plus.json http://purl.obolibrary.org/obo/GO_2001079 CHEBI:62327 biolink:ChemicalSubstance alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_62327 chebi_ph7_3 UBERON:0000389 biolink:AnatomicalEntity lens cortex Tissue that surrounds the lens nucleus go-plus.json cortex of lens http://purl.obolibrary.org/obo/UBERON_0000389 GO:2001070 biolink:MolecularActivity starch binding Binding to starch. go-plus.json amylum binding|amidon binding http://purl.obolibrary.org/obo/GO_2001070 GO:2001071 biolink:MolecularActivity maltoheptaose binding Binding to maltoheptaose. go-plus.json http://purl.obolibrary.org/obo/GO_2001071 UBERON:0000383 biolink:AnatomicalEntity musculature of body The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. go-plus.json musculature system|muscle system of body|set of muscles of body|muscle system|vertebrate muscular system|set of all muscles|muskelsystem|muscular system http://purl.obolibrary.org/obo/UBERON_0000383 CHEBI:76962 biolink:ChemicalSubstance 20-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_76962 GO:2001072 biolink:MolecularActivity galactomannan binding Binding to galactomannan. go-plus.json http://purl.obolibrary.org/obo/GO_2001072 GO:2001073 biolink:MolecularActivity cyclodextrin binding Binding to cyclodextrin. go-plus.json http://purl.obolibrary.org/obo/GO_2001073 GO:2001074 biolink:BiologicalProcess regulation of metanephric ureteric bud development Any process that modulates the frequency, rate or extent of metanephric ureteric bud development. go-plus.json http://purl.obolibrary.org/obo/GO_2001074 CHEBI:27967 biolink:ChemicalSubstance 11beta-hydroxyandrost-4-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_27967 chebi_ph7_3 CHEBI:76978 biolink:ChemicalSubstance trioctanoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_76978 chebi_ph7_3 CHEBI:76976 biolink:ChemicalSubstance bacterial xenobiotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76976 CHEBI:27969 biolink:ChemicalSubstance mesaconyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27969 UBERON:0000369 biolink:AnatomicalEntity corpus striatum The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]. go-plus.json striated body|striate body http://purl.obolibrary.org/obo/UBERON_0000369 CHEBI:27962 biolink:ChemicalSubstance pent-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27962 CHEBI:27963 biolink:ChemicalSubstance (Kdo)2-lipid A (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_27963 CHEBI:27964 biolink:ChemicalSubstance 5-methyldeoxycytidine 5'-(trihydrogen diphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_27964 CHEBI:76979 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76979 chebi_ph7_3 CHEBI:27961 biolink:ChemicalSubstance 1,8-cineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_27961 chebi_ph7_3 GO:2001086 biolink:BiologicalProcess laminarabiose transport The directed movement of a laminarabioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001086 GO:2001087 biolink:BiologicalProcess sophorose transport The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001087 GO:2001088 biolink:BiologicalProcess trisaccharide transport The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001088 GO:2001089 biolink:BiologicalProcess maltotriose transport The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001089 CHEBI:62338 biolink:ChemicalSubstance O(4)-phosphonato-L-tyrosine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62338 chebi_ph7_3 UBERON:0000376 biolink:AnatomicalEntity hindlimb stylopod The part of the hindlimb between pelvis and the knee, corresponding to the femur. go-plus.json hind propodium|hindlimb stylopodium|stylopod of hindlimb|thigh|hind limb stylopodium|hindlimb propodium|upper leg|hind limb stylopod|proximal segment of free lower limb|stylopod of hind limb|femur|stylopod of lower limb|hindlimb stylopod http://purl.obolibrary.org/obo/UBERON_0000376 UBERON:0000377 biolink:AnatomicalEntity maxillary nerve The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses. go-plus.json second division of trigeminal nerve|nervus maxillaris [v2]|ramus maxillaris (ramus V2)|maxillary division [V2]|n. maxillaris|maxillary nerve [V2]|second division of fifth cranial nerve|trigeminal V nerve maxillary division|nervus maxillaris [vb]|nervus maxillaris (Vb; V2)|maxillary division [Vb]|maxillary nerve [Vb]|trigeminal nerve maxillary division|maxillary division of fifth cranial nerve|maxillary division of trigeminal nerve (Vb; V2)|nervus maxillaris http://purl.obolibrary.org/obo/UBERON_0000377 UBERON:0000378 biolink:AnatomicalEntity tongue muscle The muscular portion of the tongue. go-plus.json muscle of tongue|tongue skeletal muscle|skeletal muscle tissue of tongue|musculi linguae|muscle organ of tongue|tongue skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0000378 GO:2001080 biolink:MolecularActivity chitosan binding Binding to chitosan. go-plus.json http://purl.obolibrary.org/obo/GO_2001080 UBERON:0000379 biolink:AnatomicalEntity tracheal mucosa A mucosa that is part of a respiratory airway. go-plus.json mucosa of windpipe|mucous membrane of windpipe|trachea mucosa|windpipe mucosa of organ|windpipe organ mucosa|mucous membrane of trachea|mucosa of trachea|tunica mucosa tracheae|tunica mucosa (tracheae)|windpipe mucous membrane|mucosa of organ of trachea|organ mucosa of windpipe|trachea organ mucosa|windpipe mucosa|organ mucosa of trachea|trachea mucosa of organ|tracheal mucous membrane|mucosa of organ of windpipe|trachea mucous membrane http://purl.obolibrary.org/obo/UBERON_0000379 GO:2001081 biolink:MolecularActivity (1->4)-beta-D-galactan binding Binding to (1->4)-beta-D-galactan. go-plus.json (1,4)-beta-D-galactan binding http://purl.obolibrary.org/obo/GO_2001081 GO:2001082 biolink:MolecularActivity inulin binding Binding to inulin. go-plus.json http://purl.obolibrary.org/obo/GO_2001082 GO:2001083 biolink:MolecularActivity alpha-D-glucan binding Binding to alpha-D-glucan. go-plus.json http://purl.obolibrary.org/obo/GO_2001083 GO:2001084 biolink:MolecularActivity L-arabinofuranose binding Binding to L-arabinofuranose. go-plus.json http://purl.obolibrary.org/obo/GO_2001084 CHEBI:76971 biolink:ChemicalSubstance Escherichia coli metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76971 UBERON:0000375 biolink:AnatomicalEntity mandibular nerve The motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini. go-plus.json mandibular nerve [Vc]|trigeminal nerve mandibular division|nervus mandibularis [vc]|nervus mandibularis [Vc; V3]|nervus mandibularis|trigeminal V nerve mandibular division|mandibular division [Vc]|n. mandibularis|mandibular nerve [V3]|mandibular division of fifth cranial nerve|third division of trigeminal nerve|inferior maxillary nerve|mandibular division of trigeminal nerve [Vc; V3]|third division of fifth cranial nerve|nervus mandibularis [v3]|ramus mandibularis (ramus V3)|mandibular division [V3] http://purl.obolibrary.org/obo/UBERON_0000375 GO:2001085 biolink:MolecularActivity arabinogalactan binding Binding to arabinogalactan. go-plus.json http://purl.obolibrary.org/obo/GO_2001085 CHEBI:27933 biolink:ChemicalSubstance beta-lactam antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_27933 CHEBI:76988 biolink:ChemicalSubstance xenoestrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_76988 CHEBI:76989 biolink:ChemicalSubstance phytoestrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_76989 CHEBI:76986 biolink:ChemicalSubstance 2-hydroxyhexacosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76986 UBERON:0000358 biolink:AnatomicalEntity blastocyst The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. go-plus.json blastocystis|blastula http://purl.obolibrary.org/obo/UBERON_0000358 CHEBI:27931 biolink:ChemicalSubstance alpha-maltotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27931 chebi_ph7_3 GO:2001097 biolink:BiologicalProcess laminaritriose transport The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001097 GO:2001098 biolink:BiologicalProcess tetrasaccharide transport The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001098 CHEBI:86315 biolink:ChemicalSubstance methyl sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_86315 chebi_ph7_3 GO:2001099 biolink:BiologicalProcess maltotetraose transport The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001099 CHEBI:62345 biolink:ChemicalSubstance L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62345 CHEBI:86316 biolink:ChemicalSubstance 3beta-hydroxychola-5,22-dien-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86316 CHEBI:86317 biolink:ChemicalSubstance 2-methyl-3-oxopalmitoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86317 CHEBI:62346 biolink:ChemicalSubstance L-rhamnopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62346 chebi_ph7_3 CHEBI:86319 biolink:ChemicalSubstance 25-hydroxyvitamin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_86319 chebi_ph7_3 UBERON:0000365 biolink:AnatomicalEntity urothelium An epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra. go-plus.json epithelium transitionale|transitional epithelium|transitional epithelium|uroepithelium http://purl.obolibrary.org/obo/UBERON_0000365 CHEBI:76980 biolink:ChemicalSubstance 2-hydroxybehenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76980 GO:2001090 biolink:BiologicalProcess maltotriulose transport The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001090 CHEBI:76981 biolink:ChemicalSubstance 3-[(1-carboxylatovinyl)oxy]benzoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76981 chebi_ph7_3 GO:2001091 biolink:BiologicalProcess nigerotriose transport The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001091 GO:2001092 biolink:BiologicalProcess arabinotriose transport The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001092 GO:2001093 biolink:BiologicalProcess galactotriose transport The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001093 CHEBI:27937 biolink:ChemicalSubstance cob(II)yrinic acid a,c diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27937 CHEBI:27938 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_27938 chebi_ph7_3 UBERON:0000362 biolink:AnatomicalEntity renal medulla the inner portion of the kidney consisting of the renal pyramids go-plus.json renal medullae set|medulla renalis|renal medullae|medullary pyramids|renal pyramids set|renal pyramids|medulla of kidney|kidney medulla|pyramides renales|renal marrow http://purl.obolibrary.org/obo/UBERON_0000362 GO:2001094 biolink:BiologicalProcess xylotriose transport The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001094 GO:2001095 biolink:BiologicalProcess mannotriose transport The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001095 CHEBI:76982 biolink:ChemicalSubstance 2,3-dioctanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76982 chebi_ph7_3 GO:2001096 biolink:BiologicalProcess cellotriose transport The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001096 CHEBI:27947 biolink:ChemicalSubstance D-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27947 UBERON:0000348 biolink:AnatomicalEntity ophthalmic nerve The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the orbit and its contents, the nasal cavity and the skin of the nose and forehead. go-plus.json profundus nerve|first division of fifth cranial nerve|ophthalmic division of trigeminal nerve (V1)|opthalmic nerve|nervus ophthalmicus [va]|ramus opthalmicus profundus (ramus V1)|nervus ophthalmicus (Va)|cranial nerve V, branch V1|ophthalmic nerve [Va]|profundus|ophthalmic division [Va]|ciliary nerve|rostral branch of trigeminal nerve|ophthalmic division|ethmoidal nerve|trigeminal nerve ophthalmic division|ophthalmic division of fifth cranial nerve|first division of trigeminal nerve|ophthalmic division of trigeminal nerve (Va)|profundal nerve|nervus ophthalmicus [v1]|trigeminal V nerve ophthalmic division|nervus ophthalmicus (V1)|first branch of fifth cranial nerve|ophthalmic nerve [V1]|ophthalmic division [V1] http://purl.obolibrary.org/obo/UBERON_0000348 CHEBI:27941 biolink:ChemicalSubstance pullulan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27941 chebi_ph7_3 UBERON:0000349 biolink:AnatomicalEntity limbic system A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]. go-plus.json visceral brain http://purl.obolibrary.org/obo/UBERON_0000349 CHEBI:86301 biolink:ChemicalSubstance 20-methyl-3-oxopregna-4,17-dien-21-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86301 CHEBI:86305 biolink:ChemicalSubstance 3beta-hydroxychol-5-en-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86305 CHEBI:86308 biolink:ChemicalSubstance 17-hydroxy-3-oxopregn-4-en-20-carboxy-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86308 UBERON:0000355 biolink:AnatomicalEntity pharyngeal mucosa A mucosa that is part of a pharynx [Automatically generated definition]. go-plus.json organ mucosa of pharynx|pharynx mucosa of organ|mucous membrane of the pharynx|pharynx mucous membrane|tunica mucosa pharyngis|pharynx organ mucosa|mucous membrane of pharynx|mucosa of pharynx|tunica mucosa pharyngea|mucosa of organ of pharynx|pharynx mucosa http://purl.obolibrary.org/obo/UBERON_0000355 CHEBI:76992 biolink:ChemicalSubstance 2-hydroxyarachidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76992 CHEBI:76990 biolink:ChemicalSubstance mycoestrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_76990 CHEBI:27948 biolink:ChemicalSubstance dTDP-alpha-D-desosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27948 UBERON:0000351 biolink:AnatomicalEntity nuchal ligament A fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebrae. go-plus.json paxwax|ligament of neck|paddywhack|ligamentum nuchae http://purl.obolibrary.org/obo/UBERON_0000351 CHEBI:27949 biolink:ChemicalSubstance (E)-sinapaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27949 chebi_ph7_3 UBERON:0000353 biolink:AnatomicalEntity parenchyma functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000353 CHEBI:144635 biolink:ChemicalSubstance D-2,4-diaminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_144635 GO:0035427 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035427 GO:0035428 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035428 GO:0035429 biolink:BiologicalProcess gluconate transmembrane transport The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose. go-plus.json gluconate membrane transport|gluconate transport http://purl.obolibrary.org/obo/GO_0035429 GO:0035420 biolink:BiologicalProcess obsolete MAPK cascade involved in innate immune response OBSOLETE. A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json MAPKKK cascade involved in innate immune response http://purl.obolibrary.org/obo/GO_0035420 GO:0035421 biolink:BiologicalProcess obsolete activation of MAPKK activity involved in innate immune response OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0035421 GO:0035422 biolink:BiologicalProcess obsolete activation of MAPKKK activity involved in innate immune response OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0035422 GO:0035423 biolink:BiologicalProcess obsolete inactivation of MAPK activity involved in innate immune response OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0035423 GO:0035424 biolink:BiologicalProcess obsolete MAPK import into nucleus involved in innate immune response OBSOLETE. The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json nuclear translocation of MAPK involved in innate immune response http://purl.obolibrary.org/obo/GO_0035424 GO:0035425 biolink:BiologicalProcess autocrine signaling Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type. go-plus.json autocrine signalling http://purl.obolibrary.org/obo/GO_0035425 GO:0035426 biolink:BiologicalProcess extracellular matrix-cell signaling Any process that mediates the transfer of information between the extracellular matrix and a cell. go-plus.json extracellular matrix-cell signalling|cell-extracellular matrix signalling http://purl.obolibrary.org/obo/GO_0035426 CHEBI:1921 biolink:ChemicalSubstance 4-oxocyclohexanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1921 CHEBI:144637 biolink:ChemicalSubstance 4-hydroxy-D-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_144637 CHEBI:37395 biolink:ChemicalSubstance mucopolysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37395 CHEBI:37392 biolink:ChemicalSubstance ribonic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37392 CHEBI:37393 biolink:ChemicalSubstance 1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37393 CHEBI:37398 biolink:ChemicalSubstance nucleotide-aldonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37398 CHEBI:37396 biolink:ChemicalSubstance proteoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_37396 CHEBI:37397 biolink:ChemicalSubstance chondroitin sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37397 GO:0035416 biolink:BiologicalProcess obsolete positive regulation of mitotic prometaphase OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. go-plus.json positive regulation of mitotic prometaphase http://purl.obolibrary.org/obo/GO_0035416 GO:0035417 biolink:BiologicalProcess obsolete negative regulation of mitotic prometaphase OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. go-plus.json negative regulation of mitotic prometaphase http://purl.obolibrary.org/obo/GO_0035417 GO:0035418 biolink:BiologicalProcess protein localization to synapse Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. go-plus.json protein localisation to synapse http://purl.obolibrary.org/obo/GO_0035418 GO:0035419 biolink:BiologicalProcess obsolete activation of MAPK activity involved in innate immune response OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0035419 GO:0035410 biolink:MolecularActivity dihydrotestosterone 17-beta-dehydrogenase activity Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH. EC:1.1.1.51 go-plus.json http://purl.obolibrary.org/obo/GO_0035410 GO:0035411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035411 GO:0035412 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035412 GO:0035413 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035413 GO:0035414 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035414 GO:0035415 biolink:BiologicalProcess obsolete regulation of mitotic prometaphase OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. go-plus.json regulation of mitotic prometaphase http://purl.obolibrary.org/obo/GO_0035415 NCBITaxon:374847 biolink:OrganismalEntity Candidatus Korarchaeum cryptofilum OPF8 go-plus.json Candidatus Korarchaeum cryptofilum strain OPF8|Candidatus Korarchaeum cryptofilum str. OPF8|korarchaeote OPF1-KOR|Korarchaeum cryptofilum OPF8 http://purl.obolibrary.org/obo/NCBITaxon_374847 NCBITaxon:1485 biolink:OrganismalEntity Clostridium go-plus.json Anaerobacter http://purl.obolibrary.org/obo/NCBITaxon_1485 GO:0035405 biolink:BiologicalProcess histone-threonine phosphorylation The modification of histones by addition of a phosphate group to a threonine residue. go-plus.json histone threonine phosphorylation http://purl.obolibrary.org/obo/GO_0035405 GO:0035406 biolink:BiologicalProcess histone-tyrosine phosphorylation The modification of histones by addition of a phosphate group to a tyrosine residue. go-plus.json histone tyrosine phosphorylation http://purl.obolibrary.org/obo/GO_0035406 GO:0035407 biolink:BiologicalProcess histone H3-T11 phosphorylation The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0035407 GO:0035408 biolink:BiologicalProcess histone H3-T6 phosphorylation The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0035408 GO:0035409 biolink:BiologicalProcess histone H3-Y41 phosphorylation The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0035409 GO:0035400 biolink:MolecularActivity histone tyrosine kinase activity Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json histone-tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0035400 GO:0035401 biolink:MolecularActivity histone kinase activity (H3-Y41 specific) Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3. go-plus.json histone-tyrosine kinase activity (H3-Y41 specific)|histone tyrosine kinase activity (H3-Y41 specific) http://purl.obolibrary.org/obo/GO_0035401 GO:0035402 biolink:MolecularActivity histone kinase activity (H3-T11 specific) Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3. go-plus.json histone threonine kinase activity (H3-T11 specific)|histone-threonine kinase activity (H3-T11 specific) http://purl.obolibrary.org/obo/GO_0035402 GO:0035403 biolink:MolecularActivity histone kinase activity (H3-T6 specific) Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3. go-plus.json histone-threonine kinase activity (H3-T6 specific)|histone threonine kinase activity (H3-T6 specific) http://purl.obolibrary.org/obo/GO_0035403 GO:0035404 biolink:BiologicalProcess histone-serine phosphorylation The modification of histones by addition of a phosphate group to a serine residue. go-plus.json histone serine phosphorylation http://purl.obolibrary.org/obo/GO_0035404 NCBITaxon:1491 biolink:OrganismalEntity Clostridium botulinum go-plus.json Clostridium putrificum|Pacinia putrifica|Botulobacillus botulinus|Bacillus putrificus|Bacillus botulinus|Ermengemillus botulinus http://purl.obolibrary.org/obo/NCBITaxon_1491 CHEBI:37373 biolink:ChemicalSubstance (S)-3-hydroxyisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37373 CHEBI:37371 biolink:ChemicalSubstance (S)-3-hydroxydecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37371 CHEBI:37374 biolink:ChemicalSubstance (S)-3-hydroxytetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37374 CHEBI:37390 biolink:ChemicalSubstance azoxy compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37390 CHEBI:52996 biolink:ChemicalSubstance alpha-D-glucosyl-(1->3)-D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_52996 chebi_ph7_3 CHEBI:52997 biolink:ChemicalSubstance D-glucopyranosyl-(1->3)-D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_52997 chebi_ph7_3 CHEBI:13389 biolink:ChemicalSubstance NAD go-plus.json http://purl.obolibrary.org/obo/CHEBI_13389 CHEBI:52994 biolink:ChemicalSubstance precursor Z go-plus.json http://purl.obolibrary.org/obo/CHEBI_52994 CHEBI:52984 biolink:ChemicalSubstance trans-2-hexacosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52984 CHEBI:52985 biolink:ChemicalSubstance 2-hexacosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52985 CHEBI:52987 biolink:ChemicalSubstance L-asparagine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_52987 UBERON:0014930 biolink:AnatomicalEntity perivascular space The space between a blood vessel and the pia mater. go-plus.json perivascular spaces|Virchow-Robin space|VRS|perivascular region http://purl.obolibrary.org/obo/UBERON_0014930 CHEBI:52980 biolink:ChemicalSubstance N-hexacosanoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52980 chebi_ph7_3 CHEBI:76900 biolink:ChemicalSubstance (3R,11Z)-3-hydroxyoctadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76900 CHEBI:52977 biolink:ChemicalSubstance 3-oxohexacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52977 CHEBI:52979 biolink:ChemicalSubstance N-tetracosanoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52979 chebi_ph7_3 UBERON:2007013 biolink:AnatomicalEntity preplacodal ectoderm Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes. go-plus.json http://purl.obolibrary.org/obo/UBERON_2007013 CHEBI:52973 biolink:ChemicalSubstance ergosteryl 3-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52973 chebi_ph7_3 CHEBI:76904 biolink:ChemicalSubstance (2E,11Z)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76904 CHEBI:52974 biolink:ChemicalSubstance tetracosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52974 CHEBI:76905 biolink:ChemicalSubstance (13Z)-3-oxoicosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76905 CHEBI:52975 biolink:ChemicalSubstance trans-2-hexacosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52975 CHEBI:76902 biolink:ChemicalSubstance EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76902 CHEBI:76908 biolink:ChemicalSubstance (3R,13Z)-3-hydroxyicosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76908 CHEBI:76909 biolink:ChemicalSubstance (2E,13Z)-icosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76909 CHEBI:76906 biolink:ChemicalSubstance EC 4.1.1.* (carboxy-lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76906 CHEBI:76907 biolink:ChemicalSubstance EC 4.2.1.* (hydro-lyases) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76907 CHEBI:1949 biolink:ChemicalSubstance 4alpha-methylzymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1949 chebi_ph7_3 CHEBI:37334 biolink:ChemicalSubstance diagnostic imaging agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_37334 CHEBI:37335 biolink:ChemicalSubstance MRI contrast agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_37335 CHEBI:1941 biolink:ChemicalSubstance 4-(trimethylammonio)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1941 CHEBI:52970 biolink:ChemicalSubstance ubiquinol-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_52970 chebi_ph7_3 CHEBI:52971 biolink:ChemicalSubstance ubiquinone-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_52971 chebi_ph7_3 CHEBI:52972 biolink:ChemicalSubstance ergosta-5,7,24(28)-trien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52972 chebi_ph7_3 CHEBI:37332 biolink:ChemicalSubstance tropane alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37332 CHEBI:37331 biolink:ChemicalSubstance (E)-penta-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37331 CHEBI:52966 biolink:ChemicalSubstance hexacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52966 CHEBI:76910 biolink:ChemicalSubstance (13Z)-icosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76910 CHEBI:52962 biolink:ChemicalSubstance N-hexacosanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52962 chebi_ph7_3 CHEBI:76915 biolink:ChemicalSubstance N,N-dimethyl-L-alaniniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_76915 CHEBI:76913 biolink:ChemicalSubstance L-cysteinate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_76913 chebi_ph7_3 CHEBI:1958 biolink:ChemicalSubstance 5'-dehydroadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_1958 chebi_ph7_3 NCBITaxon:418107 biolink:OrganismalEntity Plasmodium (Laverania) go-plus.json Laverania http://purl.obolibrary.org/obo/NCBITaxon_418107 UBERON:0014907 biolink:AnatomicalEntity intersomitic vessel One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. go-plus.json intersegmental vessel|intersomitic blood vessel|intersegmental vessels|segmental vessel|intersomitic vessels http://purl.obolibrary.org/obo/UBERON_0014907 UBERON:0014903 biolink:AnatomicalEntity primordial vasculature A portion of tissue that will develop into vasculature. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014903 CHEBI:52961 biolink:ChemicalSubstance N-tetracosanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52961 chebi_ph7_3 CHEBI:13390 biolink:ChemicalSubstance NAD(P)(+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13390 CHEBI:13392 biolink:ChemicalSubstance NAD(P)H go-plus.json http://purl.obolibrary.org/obo/CHEBI_13392 GO:0098961 biolink:BiologicalProcess dendritic transport of ribonucleoprotein complex The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites. go-plus.json dendritic transport of RNP complex http://purl.obolibrary.org/obo/GO_0098961 goslim_synapse GO:0098962 biolink:BiologicalProcess regulation of postsynaptic neurotransmitter receptor activity Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. go-plus.json http://purl.obolibrary.org/obo/GO_0098962 goslim_synapse GO:0098960 biolink:MolecularActivity postsynaptic neurotransmitter receptor activity Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission. go-plus.json neurotransmitter receptor activity involved in chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0098960 GO:1902539 biolink:BiologicalProcess multi-organism macropinocytosis A macropinocytosis which involves another organism. go-plus.json http://purl.obolibrary.org/obo/GO_1902539 GO:1902537 biolink:BiologicalProcess obsolete multi-organism pinocytosis OBSOLETE. A pinocytosis which involves another organism. go-plus.json http://purl.obolibrary.org/obo/GO_1902537 CHEBI:86293 biolink:ChemicalSubstance 3,22-dioxochol-4-en-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_86293 CHEBI:86294 biolink:ChemicalSubstance N-acyl-(4E,8E,10E)-sphinga-4,8,10-trienine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86294 chebi_ph7_3 GO:1902538 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902538 GO:1902535 biolink:BiologicalProcess multi-organism membrane invagination A membrane invagination which involves another organism. go-plus.json http://purl.obolibrary.org/obo/GO_1902535 GO:1902536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902536 GO:1902533 biolink:BiologicalProcess positive regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. go-plus.json up-regulation of signal transmission via intracellular cascade|up regulation of intracellular signal transduction|activation of intracellular signal transduction|upregulation of intracellular signaling cascade|up-regulation of intracellular signaling pathway|upregulation of intracellular signal transduction pathway|up regulation of signal transduction via intracellular signaling cascade|upregulation of signal transmission via intracellular cascade|up-regulation of intracellular signaling chain|activation of intracellular signaling cascade|positive regulation of signal transduction via intracellular signaling cascade|positive regulation of intracellular protein kinase cascade|up regulation of intracellular signaling cascade|upregulation of intracellular signaling pathway|up-regulation of intracellular signal transduction|positive regulation of intracellular signaling cascade|activation of signal transduction via intracellular signaling cascade|up regulation of intracellular signal transduction pathway|upregulation of intracellular signaling chain|positive regulation of intracellular signal transduction pathway|up regulation of signal transmission via intracellular cascade|positive regulation of signal transmission via intracellular cascade|up-regulation of signal transduction via intracellular signaling cascade|up regulation of intracellular signaling pathway|upregulation of intracellular signal transduction|activation of intracellular signal transduction pathway|positive regulation of intracellular signaling pathway|up-regulation of intracellular signaling cascade|activation of signal transmission via intracellular cascade|up regulation of intracellular signaling chain|activation of intracellular signaling chain|activation of intracellular signaling pathway|positive regulation of intracellular signaling chain|up-regulation of intracellular signal transduction pathway|upregulation of signal transduction via intracellular signaling cascade http://purl.obolibrary.org/obo/GO_1902533 GO:1902534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902534 CHEBI:86298 biolink:ChemicalSubstance O-[S-5-hexenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86298 chebi_ph7_3 GO:1902531 biolink:BiologicalProcess regulation of intracellular signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. go-plus.json regulation of intracellular signaling cascade|regulation of signal transduction via intracellular signaling cascade|regulation of intracellular signal transduction pathway|regulation of signal transmission via intracellular cascade|regulation of intracellular signaling pathway|regulation of intracellular protein kinase cascade|regulation of intracellular signaling chain http://purl.obolibrary.org/obo/GO_1902531 CHEBI:86299 biolink:ChemicalSubstance O-[S-5-hexynoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_86299 chebi_ph7_3 GO:1902532 biolink:BiologicalProcess negative regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. go-plus.json downregulation of intracellular signaling cascade|negative regulation of intracellular signaling chain|down-regulation of intracellular signaling chain|down regulation of signal transduction via intracellular signaling cascade|down-regulation of signal transmission via intracellular cascade|inhibition of intracellular signal transduction pathway|inhibition of signal transmission via intracellular cascade|downregulation of signal transduction via intracellular signaling cascade|down-regulation of intracellular signal transduction|inhibition of intracellular signaling chain|inhibition of intracellular signaling pathway|down regulation of intracellular signal transduction pathway|down regulation of signal transmission via intracellular cascade|inhibition of intracellular signal transduction|negative regulation of intracellular protein kinase cascade|negative regulation of intracellular signaling cascade|downregulation of intracellular signal transduction pathway|negative regulation of signal transduction via intracellular signaling cascade|down-regulation of signal transduction via intracellular signaling cascade|down regulation of intracellular signaling pathway|downregulation of signal transmission via intracellular cascade|down-regulation of intracellular signaling cascade|downregulation of intracellular signaling pathway|down regulation of intracellular signaling chain|inhibition of intracellular signaling cascade|negative regulation of intracellular signal transduction pathway|down-regulation of intracellular signal transduction pathway|downregulation of intracellular signaling chain|negative regulation of signal transmission via intracellular cascade|down regulation of intracellular signal transduction|inhibition of signal transduction via intracellular signaling cascade|down regulation of intracellular signaling cascade|negative regulation of intracellular signaling pathway|down-regulation of intracellular signaling pathway|downregulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902532 GO:0060350 biolink:BiologicalProcess endochondral bone morphogenesis The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. go-plus.json http://purl.obolibrary.org/obo/GO_0060350 GO:0060351 biolink:BiologicalProcess cartilage development involved in endochondral bone morphogenesis The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. go-plus.json http://purl.obolibrary.org/obo/GO_0060351 GO:0060352 biolink:BiologicalProcess cell adhesion molecule production The appearance of a cell adhesion molecule due to biosynthesis or secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0060352 GO:1902530 biolink:BiologicalProcess positive regulation of protein linear polyubiquitination Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination. go-plus.json upregulation of protein linear polyubiquitination|upregulation of M1 linkage|up regulation of protein linear polyubiquitination|activation of protein linear polyubiquitination|up-regulation of M1 linkage|activation of M1 linkage|up-regulation of protein linear polyubiquitination|positive regulation of M1 linkage|up regulation of M1 linkage http://purl.obolibrary.org/obo/GO_1902530 GO:0060353 biolink:BiologicalProcess regulation of cell adhesion molecule production Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0060353 GO:0035386 biolink:BiologicalProcess regulation of Roundabout signaling pathway Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway. go-plus.json regulation of Roundabout signalling pathway http://purl.obolibrary.org/obo/GO_0035386 GO:0060354 biolink:BiologicalProcess negative regulation of cell adhesion molecule production Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0060354 GO:0035387 biolink:BiologicalProcess negative regulation of Roundabout signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway. go-plus.json negative regulation of Roundabout signalling pathway http://purl.obolibrary.org/obo/GO_0035387 GO:0035388 biolink:BiologicalProcess positive regulation of Roundabout signaling pathway Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway. go-plus.json positive regulation of Roundabout signalling pathway http://purl.obolibrary.org/obo/GO_0035388 GO:0060355 biolink:BiologicalProcess positive regulation of cell adhesion molecule production Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0060355 GO:0060356 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0060356 GO:0035389 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035389 GO:0060357 biolink:BiologicalProcess regulation of leucine import Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle. go-plus.json regulation of L-leucine import|regulation of L-leucine uptake|regulation of leucine uptake http://purl.obolibrary.org/obo/GO_0060357 GO:0060358 biolink:BiologicalProcess negative regulation of leucine import Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0060358 GO:0060359 biolink:BiologicalProcess response to ammonium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. go-plus.json response to ammonia http://purl.obolibrary.org/obo/GO_0060359 GO:0098969 biolink:BiologicalProcess neurotransmitter receptor transport to postsynaptic membrane The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0098969 goslim_synapse GO:0035380 biolink:MolecularActivity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. go-plus.json very-long-chain-3-hydroxyacyl-CoA dehydrogenase activity http://purl.obolibrary.org/obo/GO_0035380 GO:0098967 biolink:BiologicalProcess exocytic insertion of neurotransmitter receptor to postsynaptic membrane The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0098967 goslim_synapse GO:0035381 biolink:MolecularActivity ATP-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0035381 GO:0098968 biolink:BiologicalProcess neurotransmitter receptor transport postsynaptic membrane to endosome Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098968 goslim_synapse GO:0035382 biolink:BiologicalProcess sterol transmembrane transport The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json sterol membrane transport http://purl.obolibrary.org/obo/GO_0035382 GO:0098965 biolink:CellularComponent extracellular matrix of synaptic cleft The portion of the extracellular matrix that lies within the synaptic cleft. go-plus.json synaptic cleft ECM|ECM of synaptic cleft http://purl.obolibrary.org/obo/GO_0098965 goslim_synapse GO:0098966 biolink:CellularComponent perisynaptic extracellular matrix The portion of the extracellular matrix that lies within the perisynaptic space. go-plus.json perisynaptic ECM|extrasynaptic extracellular matrix http://purl.obolibrary.org/obo/GO_0098966 goslim_synapse GO:0035383 biolink:BiologicalProcess thioester metabolic process The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. go-plus.json thioester metabolism http://purl.obolibrary.org/obo/GO_0035383 GO:0098963 biolink:BiologicalProcess dendritic transport of messenger ribonucleoprotein complex The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites. go-plus.json dendritic transport of mRNA RNP complex http://purl.obolibrary.org/obo/GO_0098963 goslim_synapse GO:0035384 biolink:BiologicalProcess thioester biosynthetic process The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. go-plus.json thioester biosynthesis|thioester anabolism|thioester synthesis|thioester formation http://purl.obolibrary.org/obo/GO_0035384 GO:0098964 biolink:BiologicalProcess anterograde dendritic transport of messenger ribonucleoprotein complex The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse. go-plus.json anterograde dendritic transport of mRNA RNP complex http://purl.obolibrary.org/obo/GO_0098964 goslim_synapse GO:0035385 biolink:BiologicalProcess Roundabout signaling pathway A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json ROBO signaling pathway|ROBO/SLIT signaling pathway|Roundabout signalling pathway http://purl.obolibrary.org/obo/GO_0035385 GO:0098972 biolink:BiologicalProcess anterograde dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body. go-plus.json http://purl.obolibrary.org/obo/GO_0098972 goslim_synapse GO:0098973 biolink:MolecularActivity structural constituent of postsynaptic actin cytoskeleton The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0098973 goslim_synapse GO:0098970 biolink:BiologicalProcess postsynaptic neurotransmitter receptor diffusion trapping The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization. go-plus.json http://purl.obolibrary.org/obo/GO_0098970 goslim_synapse GO:0098971 biolink:BiologicalProcess anterograde dendritic transport of neurotransmitter receptor complex The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0098971 goslim_synapse GO:1902548 biolink:BiologicalProcess negative regulation of cellular response to vascular endothelial growth factor stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus. go-plus.json downregulation of cellular response to vascular endothelial growth factor|downregulation of cellular response to VEGF|downregulation of cellular response to VEGFB|downregulation of cellular response to VEGFA|negative regulation of cellular response to vascular endothelial growth factor|down-regulation of cellular response to vascular endothelial growth factor|down regulation of cellular response to VEGFB|down regulation of cellular response to VEGFA|down-regulation of cellular response to VEGF|down-regulation of cellular response to vascular endothelial growth factor stimulus|negative regulation of cellular response to VEGF|inhibition of cellular response to VEGFB|inhibition of cellular response to vascular endothelial growth factor|inhibition of cellular response to VEGFA|inhibition of cellular response to VEGF|downregulation of cellular response to vascular endothelial growth factor stimulus|down regulation of cellular response to vascular endothelial growth factor stimulus|inhibition of cellular response to vascular endothelial growth factor stimulus|down regulation of cellular response to vascular endothelial growth factor|down-regulation of cellular response to VEGFB|negative regulation of cellular response to VEGFB|down-regulation of cellular response to VEGFA|negative regulation of cellular response to VEGFA|down regulation of cellular response to VEGF http://purl.obolibrary.org/obo/GO_1902548 GO:1902549 biolink:BiologicalProcess protein localization to Mei2 nuclear dot A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot. go-plus.json protein localization to Mei2 dot|protein localisation to Mei2 nuclear dot|protein localisation in Mei2 nuclear dot|protein localization in Mei2 nuclear dot http://purl.obolibrary.org/obo/GO_1902549 CHEBI:86284 biolink:ChemicalSubstance CMP-3-deoxy-beta-D-manno-octulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86284 GO:1902546 biolink:BiologicalProcess positive regulation of DNA N-glycosylase activity Any process that activates or increases the frequency, rate or extent of DNA N-glycosylase activity. go-plus.json up-regulation of DNA glycosylase activity|up-regulation of DNA N-glycosylase activity|activation of DNA glycosylase activity|up-regulation of endonuclease VIII activity|activation of DNA N-glycosylase activity|activation of endonuclease VIII activity|positive regulation of DNA glycosylase activity|up regulation of DNA glycosylase activity|positive regulation of endonuclease VIII activity|up regulation of DNA N-glycosylase activity|up regulation of endonuclease VIII activity|upregulation of DNA glycosylase activity|upregulation of DNA N-glycosylase activity|upregulation of endonuclease VIII activity http://purl.obolibrary.org/obo/GO_1902546 GO:1902547 biolink:BiologicalProcess regulation of cellular response to vascular endothelial growth factor stimulus Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus. go-plus.json regulation of cellular response to VEGFB|regulation of cellular response to VEGFA|regulation of cellular response to vascular endothelial growth factor|regulation of cellular response to VEGF http://purl.obolibrary.org/obo/GO_1902547 GO:1902544 biolink:BiologicalProcess regulation of DNA N-glycosylase activity Any process that modulates the frequency, rate or extent of DNA N-glycosylase activity. go-plus.json regulation of DNA glycosylase activity|regulation of endonuclease VIII activity http://purl.obolibrary.org/obo/GO_1902544 CHEBI:86287 biolink:ChemicalSubstance GDP-N,N'-diacetylbacillosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86287 GO:1902545 biolink:BiologicalProcess negative regulation of DNA N-glycosylase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA N-glycosylase activity. go-plus.json inhibition of endonuclease VIII activity|down-regulation of DNA glycosylase activity|negative regulation of DNA glycosylase activity|negative regulation of endonuclease VIII activity|down-regulation of endonuclease VIII activity|down-regulation of DNA N-glycosylase activity|downregulation of DNA glycosylase activity|downregulation of DNA N-glycosylase activity|downregulation of endonuclease VIII activity|down regulation of DNA glycosylase activity|down regulation of endonuclease VIII activity|down regulation of DNA N-glycosylase activity|inhibition of DNA glycosylase activity|inhibition of DNA N-glycosylase activity http://purl.obolibrary.org/obo/GO_1902545 GO:1902542 biolink:BiologicalProcess regulation of protein localization to mitotic spindle pole body Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body. go-plus.json regulation of protein localisation to mitotic spindle pole body http://purl.obolibrary.org/obo/GO_1902542 GO:1902543 biolink:BiologicalProcess negative regulation of protein localization to mitotic spindle pole body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body. go-plus.json down regulation of protein localization to mitotic spindle pole body|downregulation of protein localization to mitotic spindle pole body|down regulation of protein localisation to mitotic spindle pole body|down-regulation of protein localisation in mitotic spindle pole body|downregulation of protein localisation to mitotic spindle pole body|down-regulation of protein localization to mitotic spindle pole body|inhibition of protein localization to mitotic spindle pole body|down-regulation of protein localisation to mitotic spindle pole body|negative regulation of protein localisation to mitotic spindle pole body|inhibition of protein localisation to mitotic spindle pole body http://purl.obolibrary.org/obo/GO_1902543 GO:0060340 biolink:BiologicalProcess positive regulation of type I interferon-mediated signaling pathway Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. go-plus.json positive regulation of type I interferon-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0060340 GO:1902540 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902540 GO:1902541 biolink:BiologicalProcess multi-organism micropinocytosis A micropinocytosis which involves another organism. go-plus.json http://purl.obolibrary.org/obo/GO_1902541 GO:0060341 biolink:BiologicalProcess regulation of cellular localization Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. go-plus.json regulation of cellular localisation http://purl.obolibrary.org/obo/GO_0060341 GO:0060342 biolink:CellularComponent photoreceptor inner segment membrane The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. go-plus.json http://purl.obolibrary.org/obo/GO_0060342 GO:0035375 biolink:MolecularActivity zymogen binding Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis. go-plus.json proenzyme binding http://purl.obolibrary.org/obo/GO_0035375 GO:0060343 biolink:BiologicalProcess trabecula formation The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. go-plus.json trabecula biogenesis|trabeculation http://purl.obolibrary.org/obo/GO_0060343 GO:1902550 biolink:BiologicalProcess lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis. go-plus.json lymphoid lineage cell migration into thymus involved in thymic epithelium morphogenesis|lymphoid lineage restricted progenitor cell migration into thymus involved in thymic epithelium morphogenesis|lymphoid lineage restricted progenitor cell migration into thymus involved in thymus epithelium morphogenesis http://purl.obolibrary.org/obo/GO_1902550 GO:0035376 biolink:BiologicalProcess sterol import The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json sterol uptake|sterol influx http://purl.obolibrary.org/obo/GO_0035376 GO:0060344 biolink:BiologicalProcess liver trabecula formation The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. go-plus.json liver trabeculation|liver trabecula biogenesis http://purl.obolibrary.org/obo/GO_0060344 GO:0035377 biolink:BiologicalProcess transepithelial water transport The directed movement of water (H2O) from one side of an epithelium to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0035377 GO:0060345 biolink:BiologicalProcess spleen trabecula formation The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. go-plus.json spleen trabecula biogenesis|spleen trabeculation http://purl.obolibrary.org/obo/GO_0060345 GO:0035378 biolink:BiologicalProcess carbon dioxide transmembrane transport The process in which carbon dioxide (CO2) is transported across a membrane. go-plus.json carbon dioxide membrane transport http://purl.obolibrary.org/obo/GO_0035378 GO:0035379 biolink:MolecularActivity carbon dioxide transmembrane transporter activity Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other. Reactome:R-HSA-1247649|Reactome:R-HSA-1237069|Reactome:R-HSA-1247645|Reactome:R-HSA-1237042 go-plus.json http://purl.obolibrary.org/obo/GO_0035379 GO:0060346 biolink:BiologicalProcess bone trabecula formation The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod. go-plus.json bone trabecula biogenesis|bone trabeculation|skeletal trabeculation|skeletal trabecula formation|skeletal trabecula biogenesis http://purl.obolibrary.org/obo/GO_0060346 GO:0060347 biolink:BiologicalProcess heart trabecula formation The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. go-plus.json heart trabecula biogenesis|heart trabeculation|cardiac trabeculation|cardiac trabecula formation http://purl.obolibrary.org/obo/GO_0060347 GO:0060348 biolink:BiologicalProcess bone development The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. go-plus.json http://purl.obolibrary.org/obo/GO_0060348 CHEBI:129091 biolink:ChemicalSubstance (9Z,12R)-12,18-dihydroxyoctadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_129091 GO:0060349 biolink:BiologicalProcess bone morphogenesis The process in which bones are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060349 GO:0098978 biolink:CellularComponent glutamatergic synapse A synapse that uses glutamate as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0098978 goslim_synapse GO:0035370 biolink:CellularComponent UBC13-UEV1A complex A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A). go-plus.json http://purl.obolibrary.org/obo/GO_0035370 GO:0098979 biolink:CellularComponent polyadic synapse A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems. go-plus.json http://purl.obolibrary.org/obo/GO_0098979 GO:0035371 biolink:CellularComponent microtubule plus-end The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability. go-plus.json microtubule plus end|growing microtubule plus end http://purl.obolibrary.org/obo/GO_0035371 GO:0098976 biolink:BiologicalProcess excitatory chemical synaptic transmission Synaptic transmission that results in an excitatory postsynaptic potential. go-plus.json http://purl.obolibrary.org/obo/GO_0098976 GO:0098977 biolink:BiologicalProcess inhibitory chemical synaptic transmission Synaptic transmission that results in an inhibitory postsynaptic potential. go-plus.json http://purl.obolibrary.org/obo/GO_0098977 GO:0035372 biolink:BiologicalProcess protein localization to microtubule A process in which a protein is transported to, or maintained at, a microtubule. go-plus.json protein localisation to microtubule http://purl.obolibrary.org/obo/GO_0035372 GO:0098974 biolink:BiologicalProcess postsynaptic actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0098974 goslim_synapse GO:0035373 biolink:MolecularActivity chondroitin sulfate proteoglycan binding Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit. go-plus.json http://purl.obolibrary.org/obo/GO_0035373 CHEBI:130073 biolink:ChemicalSubstance 5,20-diHEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_130073 GO:0035374 biolink:MolecularActivity chondroitin sulfate binding Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). go-plus.json http://purl.obolibrary.org/obo/GO_0035374 GO:0098975 biolink:CellularComponent postsynapse of neuromuscular junction The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma. go-plus.json http://purl.obolibrary.org/obo/GO_0098975 GO:0098940 biolink:BiologicalProcess anterograde trans-synaptic signaling by nitric oxide Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide. go-plus.json http://purl.obolibrary.org/obo/GO_0098940 goslim_synapse GO:1902559 biolink:BiologicalProcess 3'-phospho-5'-adenylyl sulfate transmembrane transport The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane. go-plus.json 3'-phosphoadenosine 5'-phosphosulfate transmembrane transport http://purl.obolibrary.org/obo/GO_1902559 GO:1902557 biolink:MolecularActivity 5'-adenylyl sulfate transmembrane transporter activity Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1902557 CHEBI:1989 biolink:ChemicalSubstance (6R)-5,10-methylenetetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1989 GO:1902558 biolink:BiologicalProcess 5'-adenylyl sulfate transmembrane transport The process in which 5'-adenylyl sulfate is transported across a membrane. go-plus.json adenosine 5'-phosphosulfate transmembrane transport http://purl.obolibrary.org/obo/GO_1902558 GO:1902555 biolink:CellularComponent endoribonuclease complex A protein complex which is capable of endoribonuclease activity. go-plus.json Ire1 complex homodimer|Ire1 complex homooligomer|Ire1 complex dimer http://purl.obolibrary.org/obo/GO_1902555 GO:1902556 biolink:CellularComponent phosphatidylinositol transporter complex A protein complex which is capable of phosphatidylinositol transporter activity. go-plus.json Ire1 complex dimer|Ire1 complex homodimer|Ire1 complex homooligomer http://purl.obolibrary.org/obo/GO_1902556 GO:0060370 biolink:BiologicalProcess susceptibility to T cell mediated cytotoxicity The process of causing a cell to become susceptible to T cell mediated cytotoxicity. go-plus.json http://purl.obolibrary.org/obo/GO_0060370 GO:1902553 biolink:BiologicalProcess positive regulation of catalase activity Any process that activates or increases the frequency, rate or extent of catalase activity. go-plus.json upregulation of CAT|activation of haem catalase activity|up-regulation of equilase activity|up regulation of caperase activity|activation of caperase activity|activation of manganese catalase activity|positive regulation of caperase activity|up-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|upregulation of bacterial catalase-peroxidase activity|up regulation of catalase reaction|activation of catalase reaction|positive regulation of haem catalase activity|up-regulation of heme catalase activity|positive regulation of catalase reaction|upregulation of optidase activity|positive regulation of catalase-peroxidase activity|up regulation of haem catalase activity|up-regulation of manganese catalase activity|upregulation of equilase activity|up regulation of catalase-peroxidase activity|up regulation of CAT|up-regulation of catalase activity|activation of heme catalase activity|positive regulation of CAT|up-regulation of caperase activity|up-regulation of bacterial catalase-peroxidase activity|upregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|positive regulation of heme catalase activity|up-regulation of catalase reaction|upregulation of haem catalase activity|activation of CAT|up regulation of optidase activity|upregulation of manganese catalase activity|activation of optidase activity|up regulation of heme catalase activity|positive regulation of optidase activity|up regulation of equilase activity|activation of bacterial catalase-peroxidase activity|upregulation of catalase-peroxidase activity|activation of equilase activity|upregulation of catalase activity|positive regulation of equilase activity|upregulation of caperase activity|up-regulation of CAT|up regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|activation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|positive regulation of bacterial catalase-peroxidase activity|positive regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|up-regulation of haem catalase activity|up regulation of bacterial catalase-peroxidase activity|upregulation of catalase reaction|up regulation of manganese catalase activity|activation of catalase-peroxidase activity|up-regulation of catalase-peroxidase activity|positive regulation of manganese catalase activity|upregulation of heme catalase activity|up-regulation of optidase activity|up regulation of catalase activity|activation of catalase activity http://purl.obolibrary.org/obo/GO_1902553 GO:0060371 biolink:BiologicalProcess regulation of atrial cardiac muscle cell membrane depolarization Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte. go-plus.json electrocardiogram PR interval|regulation of atrial cardiac muscle cell depolarization|atrial depolarization|regulation of atrial cardiomyocyte membrane depolarization http://purl.obolibrary.org/obo/GO_0060371 GO:0060372 biolink:BiologicalProcess regulation of atrial cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte. go-plus.json atrial repolarization|regulation of atrial cardiomyocyte membrane repolarization|electrocardiogram QRS complex|regulation of atrial cardiac muscle cell repolarization http://purl.obolibrary.org/obo/GO_0060372 GO:1902554 biolink:CellularComponent serine/threonine protein kinase complex A protein complex which is capable of protein serine/threonine kinase activity. go-plus.json PDR16 complex dimer|PDR16 complex homodimer http://purl.obolibrary.org/obo/GO_1902554 GO:0060373 biolink:BiologicalProcess regulation of ventricular cardiac muscle cell membrane depolarization Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte. go-plus.json ventricular depolarization|electrocardiogram QRS complex|regulation of ventricular cardiomyocyte membrane depolarization http://purl.obolibrary.org/obo/GO_0060373 GO:1902551 biolink:BiologicalProcess regulation of catalase activity Any process that modulates the frequency, rate or extent of catalase activity. go-plus.json regulation of CAT|regulation of optidase activity|regulation of haem catalase activity|regulation of equilase activity|regulation of catalase-peroxidase activity|regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|regulation of manganese catalase activity|regulation of heme catalase activity|regulation of caperase activity|regulation of bacterial catalase-peroxidase activity|regulation of catalase reaction http://purl.obolibrary.org/obo/GO_1902551 GO:0060374 biolink:BiologicalProcess mast cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. go-plus.json http://purl.obolibrary.org/obo/GO_0060374 GO:1902552 biolink:BiologicalProcess negative regulation of catalase activity Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity. go-plus.json downregulation of catalase reaction|down-regulation of haem catalase activity|negative regulation of haem catalase activity|down-regulation of manganese catalase activity|inhibition of heme catalase activity|negative regulation of manganese catalase activity|down regulation of bacterial catalase-peroxidase activity|down regulation of CAT|down-regulation of catalase-peroxidase activity|negative regulation of catalase-peroxidase activity|inhibition of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down-regulation of catalase activity|down-regulation of caperase activity|negative regulation of caperase activity|downregulation of CAT|inhibition of bacterial catalase-peroxidase activity|down regulation of optidase activity|down-regulation of catalase reaction|negative regulation of catalase reaction|inhibition of catalase activity|downregulation of haem catalase activity|downregulation of catalase-peroxidase activity|down regulation of equilase activity|inhibition of caperase activity|down-regulation of heme catalase activity|downregulation of optidase activity|negative regulation of heme catalase activity|inhibition of manganese catalase activity|down regulation of haem catalase activity|down regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|downregulation of equilase activity|down regulation of catalase-peroxidase activity|down-regulation of CAT|negative regulation of CAT|inhibition of catalase reaction|inhibition of catalase-peroxidase activity|downregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down regulation of manganese catalase activity|negative regulation of bacterial catalase-peroxidase activity|down-regulation of bacterial catalase-peroxidase activity|inhibition of haem catalase activity|down regulation of catalase activity|negative regulation of optidase activity|down-regulation of optidase activity|downregulation of heme catalase activity|down regulation of caperase activity|down-regulation of equilase activity|negative regulation of equilase activity|downregulation of manganese catalase activity|down regulation of heme catalase activity|downregulation of catalase activity|inhibition of CAT|down regulation of catalase reaction|downregulation of caperase activity|negative regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|downregulation of bacterial catalase-peroxidase activity|inhibition of optidase activity|inhibition of equilase activity http://purl.obolibrary.org/obo/GO_1902552 GO:0035364 biolink:BiologicalProcess thymine transport The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json thymine transmembrane transport|5-methyluracil transport http://purl.obolibrary.org/obo/GO_0035364 GO:0060375 biolink:BiologicalProcess regulation of mast cell differentiation Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. go-plus.json http://purl.obolibrary.org/obo/GO_0060375 GO:1902560 biolink:CellularComponent GMP reductase complex An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+). go-plus.json guanosine monophosphate reductase|GMPR2 complex|GMPR1 complex|GMP reductase http://purl.obolibrary.org/obo/GO_1902560 GO:0060376 biolink:BiologicalProcess positive regulation of mast cell differentiation Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. go-plus.json http://purl.obolibrary.org/obo/GO_0060376 GO:0035365 biolink:BiologicalProcess regulation of thymine transport Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of 5-methyluracil transport http://purl.obolibrary.org/obo/GO_0035365 GO:1902561 biolink:BiologicalProcess origin recognition complex assembly The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex. go-plus.json ORC assembly|origin of replication recognition complex assembly|origin recognition complex formation|origin of replication recognition complex formation|ORC formation http://purl.obolibrary.org/obo/GO_1902561 GO:0060377 biolink:BiologicalProcess negative regulation of mast cell differentiation Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. go-plus.json http://purl.obolibrary.org/obo/GO_0060377 GO:0035366 biolink:BiologicalProcess negative regulation of thymine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json negative regulation of 5-methyluracil transport http://purl.obolibrary.org/obo/GO_0035366 GO:0060378 biolink:BiologicalProcess regulation of brood size Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time. go-plus.json http://purl.obolibrary.org/obo/GO_0060378 GO:0035367 biolink:BiologicalProcess positive regulation of thymine transport Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json positive regulation of 5-methyluracil transport http://purl.obolibrary.org/obo/GO_0035367 GO:0060379 biolink:BiologicalProcess cardiac muscle cell myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. go-plus.json cardiac myoblast differentiation|myocardial precursor cell differentiation http://purl.obolibrary.org/obo/GO_0060379 GO:0035368 biolink:MolecularActivity selenocysteine insertion sequence binding Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation. go-plus.json SECIS binding http://purl.obolibrary.org/obo/GO_0035368 GO:0035369 biolink:CellularComponent pre-B cell receptor complex An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json pre-BCR http://purl.obolibrary.org/obo/GO_0035369 GO:0098949 biolink:CellularComponent intrinsic component of postsynaptic endosome membrane The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic endosome membrane http://purl.obolibrary.org/obo/GO_0098949 goslim_synapse GO:0098947 biolink:CellularComponent intrinsic component of postsynaptic endocytic zone membrane The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic acive zone membrane http://purl.obolibrary.org/obo/GO_0098947 goslim_synapse GO:0098948 biolink:CellularComponent intrinsic component of postsynaptic specialization membrane The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic specialization membrane http://purl.obolibrary.org/obo/GO_0098948 goslim_synapse GO:0098945 biolink:CellularComponent intrinsic component of presynaptic active zone membrane The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to presynaptic acive zone membrane http://purl.obolibrary.org/obo/GO_0098945 goslim_synapse GO:0098946 biolink:CellularComponent intrinsic component of presynaptic endocytic zone membrane The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to presynaptic acive zone membrane http://purl.obolibrary.org/obo/GO_0098946 goslim_synapse GO:0035360 biolink:BiologicalProcess positive regulation of peroxisome proliferator activated receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. go-plus.json positive regulation of PPAR signaling pathway|positive regulation of peroxisome proliferator-activated receptor signaling pathway|positive regulation of peroxisome proliferator activated receptor signalling pathway http://purl.obolibrary.org/obo/GO_0035360 GO:0098943 biolink:BiologicalProcess neurotransmitter receptor transport, postsynaptic endosome to lysosome The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation. go-plus.json postsynaptic neurotransmitter receptor endosomal trafficking http://purl.obolibrary.org/obo/GO_0098943 goslim_synapse GO:0035361 biolink:CellularComponent Cul8-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0035361 GO:0098944 biolink:CellularComponent postsynaptic recycling endosome membrane The lipid bilayer surrounding a postsynaptic recycling endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098944 goslim_synapse GO:0098941 biolink:BiologicalProcess anterograde trans-synaptic signaling by trans-synaptic protein complex Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0098941 goslim_synapse GO:0035362 biolink:BiologicalProcess protein-DNA ISRE complex assembly The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA. go-plus.json protein-DNA interferon-stimulated response element complex assembly http://purl.obolibrary.org/obo/GO_0035362 GO:0098942 biolink:BiologicalProcess retrograde trans-synaptic signaling by trans-synaptic protein complex Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0098942 goslim_synapse GO:0035363 biolink:CellularComponent histone locus body A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body. go-plus.json HLB http://purl.obolibrary.org/obo/GO_0035363 GO:0098950 biolink:CellularComponent intrinsic component of postsynaptic early endosome membrane The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic early endosome membrane http://purl.obolibrary.org/obo/GO_0098950 goslim_synapse GO:0098951 biolink:CellularComponent intrinsic component of postsynaptic recycling endosome membrane The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic recycling endosome membrane http://purl.obolibrary.org/obo/GO_0098951 goslim_synapse GO:2001105 biolink:BiologicalProcess maltoheptaose transport The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001105 GO:1902568 biolink:BiologicalProcess positive regulation of eosinophil activation Any process that activates or increases the frequency, rate or extent of eosinophil activation. go-plus.json upregulation of eosinophil activation|up regulation of eosinophil activation|activation of eosinophil activation|up-regulation of eosinophil activation http://purl.obolibrary.org/obo/GO_1902568 GO:1902569 biolink:BiologicalProcess negative regulation of activation of Janus kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity. go-plus.json down-regulation of activation of JAK1 protein|negative regulation of activation of JAK1 protein|downregulation of activation of JAK1 kinase activity|down regulation of tyrosine phosphorylation of JAK2 protein|inhibition of activation of JAK2 protein|down regulation of activation of JAK1 kinase activity|downregulation of tyrosine phosphorylation of JAK1 protein|down-regulation of activation of JAK2 kinase activity|inhibition of tyrosine phosphorylation of JAK2 protein|downregulation of activation of JAK1 protein|down regulation of tyrosine phosphorylation of JAK1 protein|down-regulation of tyrosine phosphorylation of JAK2 protein|inhibition of activation of JAK1 kinase activity|down regulation of activation of JAK1 protein|downregulation of activation of JAK2 kinase activity|negative regulation of activation of JAK2 protein|down-regulation of activation of JAK2 protein|inhibition of tyrosine phosphorylation of JAK1 protein|down regulation of activation of JAK2 kinase activity|inhibition of activation of JAK1 protein|negative regulation of tyrosine phosphorylation of JAK2 protein|negative regulation of activation of JAK2 kinase activity|down-regulation of activation of JAK1 kinase activity|inhibition of activation of JAK2 kinase activity|down regulation of activation of JAK2 protein|negative regulation of tyrosine phosphorylation of JAK1 protein|down-regulation of tyrosine phosphorylation of JAK1 protein|downregulation of tyrosine phosphorylation of JAK2 protein http://purl.obolibrary.org/obo/GO_1902569 GO:2001106 biolink:BiologicalProcess regulation of Rho guanyl-nucleotide exchange factor activity Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. go-plus.json regulation of Rho guanine nucleotide exchange factor|regulation of RhoGEF http://purl.obolibrary.org/obo/GO_2001106 GO:1902566 biolink:BiologicalProcess regulation of eosinophil activation Any process that modulates the frequency, rate or extent of eosinophil activation. go-plus.json http://purl.obolibrary.org/obo/GO_1902566 GO:2001107 biolink:BiologicalProcess negative regulation of Rho guanyl-nucleotide exchange factor activity Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. go-plus.json negative regulation of RhoGEF|negative regulation of Rho guanine nucleotide exchange factor http://purl.obolibrary.org/obo/GO_2001107 GO:1902567 biolink:BiologicalProcess negative regulation of eosinophil activation Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation. go-plus.json down regulation of eosinophil activation|downregulation of eosinophil activation|down-regulation of eosinophil activation|inhibition of eosinophil activation http://purl.obolibrary.org/obo/GO_1902567 GO:2001108 biolink:BiologicalProcess positive regulation of Rho guanyl-nucleotide exchange factor activity Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. go-plus.json positive regulation of RhoGEF|positive regulation of Rho guanine nucleotide exchange factor http://purl.obolibrary.org/obo/GO_2001108 GO:1902564 biolink:BiologicalProcess negative regulation of neutrophil activation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation. go-plus.json down-regulation of neutrophil activation|inhibition of neutrophil activation|down regulation of neutrophil activation|downregulation of neutrophil activation http://purl.obolibrary.org/obo/GO_1902564 GO:2001109 biolink:BiologicalProcess regulation of lens epithelial cell proliferation Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2001109 GO:0060360 biolink:BiologicalProcess negative regulation of leucine import in response to ammonium ion Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle. go-plus.json negative regulation of leucine uptake in response to ammonium ion http://purl.obolibrary.org/obo/GO_0060360 GO:1902565 biolink:BiologicalProcess positive regulation of neutrophil activation Any process that activates or increases the frequency, rate or extent of neutrophil activation. go-plus.json up regulation of neutrophil activation|activation of neutrophil activation|up-regulation of neutrophil activation|upregulation of neutrophil activation http://purl.obolibrary.org/obo/GO_1902565 GO:0060361 biolink:BiologicalProcess flight Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement. go-plus.json http://purl.obolibrary.org/obo/GO_0060361 GO:1902562 biolink:CellularComponent H4 histone acetyltransferase complex A protein complex which is capable of H4 histone acetyltransferase activity. go-plus.json Hpa3 (homo-)dimer|Hpa3 complex http://purl.obolibrary.org/obo/GO_1902562 GO:0060362 biolink:BiologicalProcess flight involved in flight behavior Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight. go-plus.json http://purl.obolibrary.org/obo/GO_0060362 GO:0060363 biolink:BiologicalProcess cranial suture morphogenesis The process in which any suture between cranial bones is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060363 GO:1902563 biolink:BiologicalProcess regulation of neutrophil activation Any process that modulates the frequency, rate or extent of neutrophil activation. go-plus.json http://purl.obolibrary.org/obo/GO_1902563 GO:1902571 biolink:BiologicalProcess regulation of serine-type peptidase activity Any process that modulates the frequency, rate or extent of serine-type peptidase activity. go-plus.json regulation of serine protease activity http://purl.obolibrary.org/obo/GO_1902571 GO:0060364 biolink:BiologicalProcess frontal suture morphogenesis The process in which the frontal suture is generated and organized. go-plus.json interfrontal suture morphogenesis http://purl.obolibrary.org/obo/GO_0060364 GO:0035353 biolink:BiologicalProcess nicotinamide mononucleotide transmembrane transport The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP. go-plus.json nicotinamide mononucleotide membrane transport http://purl.obolibrary.org/obo/GO_0035353 GO:0035354 biolink:CellularComponent Toll-like receptor 1-Toll-like receptor 2 protein complex A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2). go-plus.json TLR1:TLR2 complex|TLR1-TLR2 protein complex|TLR2:TLR1 heterodimer|toll-like receptor TLR1:TLR2 heterodimeric complex http://purl.obolibrary.org/obo/GO_0035354 GO:1902572 biolink:BiologicalProcess negative regulation of serine-type peptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity. go-plus.json downregulation of serine-type peptidase activity|down-regulation of serine protease activity|negative regulation of serine protease activity|down regulation of serine-type peptidase activity|inhibition of serine-type peptidase activity|downregulation of serine protease activity|down regulation of serine protease activity|inhibition of serine protease activity|down-regulation of serine-type peptidase activity http://purl.obolibrary.org/obo/GO_1902572 GO:0060365 biolink:BiologicalProcess coronal suture morphogenesis The process in which the coronal suture is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060365 GO:0035355 biolink:CellularComponent Toll-like receptor 2-Toll-like receptor 6 protein complex A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6). go-plus.json toll-like receptor TLR6:TLR2 heterodimeric complex|TLR6:TLR2 complex|TLR2-TLR6 protein complex|TLR2:TLR6 heterodimer http://purl.obolibrary.org/obo/GO_0035355 GO:0060366 biolink:BiologicalProcess lambdoid suture morphogenesis The process in which the lambdoid suture is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060366 GO:0035356 biolink:BiologicalProcess cellular triglyceride homeostasis Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment. go-plus.json http://purl.obolibrary.org/obo/GO_0035356 GO:2001100 biolink:BiologicalProcess pentasaccharide transport The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001100 GO:1902570 biolink:BiologicalProcess protein localization to nucleolus A process in which a protein is transported to, or maintained in, a location within a nucleolus. go-plus.json protein localisation in nucleolus|protein localisation to nucleolus|protein localization in nucleolus http://purl.obolibrary.org/obo/GO_1902570 GO:0060367 biolink:BiologicalProcess sagittal suture morphogenesis The process in which the sagittal suture is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0060367 GO:2001101 biolink:BiologicalProcess maltopentaose transport The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001101 GO:0035357 biolink:BiologicalProcess peroxisome proliferator activated receptor signaling pathway The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes. go-plus.json peroxisome proliferator activated receptor signalling pathway|PPAR signaling pathway|peroxisome proliferator-activated receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035357 GO:0060368 biolink:BiologicalProcess regulation of Fc receptor mediated stimulatory signaling pathway Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json regulation of Fc receptor mediated stimulatory signalling pathway http://purl.obolibrary.org/obo/GO_0060368 GO:0035358 biolink:BiologicalProcess regulation of peroxisome proliferator activated receptor signaling pathway Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. go-plus.json regulation of peroxisome proliferator activated receptor signalling pathway|regulation of PPAR signaling pathway|regulation of peroxisome proliferator-activated receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035358 GO:2001102 biolink:BiologicalProcess hexasaccharide transport The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001102 GO:0060369 biolink:BiologicalProcess positive regulation of Fc receptor mediated stimulatory signaling pathway Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json positive regulation of Fc receptor mediated stimulatory signalling pathway http://purl.obolibrary.org/obo/GO_0060369 GO:0035359 biolink:BiologicalProcess negative regulation of peroxisome proliferator activated receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. go-plus.json negative regulation of peroxisome proliferator activated receptor signalling pathway|negative regulation of PPAR signaling pathway|negative regulation of peroxisome proliferator-activated receptor signaling pathway http://purl.obolibrary.org/obo/GO_0035359 GO:2001103 biolink:BiologicalProcess maltohexaose transport The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001103 GO:2001104 biolink:BiologicalProcess heptasaccharide transport The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001104 GO:0098958 biolink:BiologicalProcess retrograde axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse. go-plus.json retrograde axon transport of mitochondria http://purl.obolibrary.org/obo/GO_0098958 goslim_synapse GO:0098959 biolink:BiologicalProcess retrograde dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse. go-plus.json retrograde dendrite transport of mitochondria http://purl.obolibrary.org/obo/GO_0098959 goslim_synapse GO:0098956 biolink:CellularComponent intrinsic component of dense core granule membrane The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to dense core granule membrane http://purl.obolibrary.org/obo/GO_0098956 GO:0098957 biolink:BiologicalProcess anterograde axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. go-plus.json anterograde axon transport of mitochondria http://purl.obolibrary.org/obo/GO_0098957 goslim_synapse GO:0098954 biolink:CellularComponent presynaptic endosome membrane The lipid bilayer surrounding a presynaptic endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098954 goslim_synapse GO:0098955 biolink:CellularComponent intrinsic component of presynaptic endosome membrane The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to presynaptic endosome membrane http://purl.obolibrary.org/obo/GO_0098955 goslim_synapse GO:0035350 biolink:BiologicalProcess FAD transmembrane transport The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. go-plus.json FAD membrane transport http://purl.obolibrary.org/obo/GO_0035350 GO:0035351 biolink:BiologicalProcess heme transmembrane transport The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json heme membrane transport http://purl.obolibrary.org/obo/GO_0035351 GO:0098952 biolink:CellularComponent intrinsic component of spine apparatus membrane The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to spine apparatus membrane http://purl.obolibrary.org/obo/GO_0098952 goslim_synapse GO:0035352 biolink:BiologicalProcess NAD transmembrane transport The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json NAD membrane transport http://purl.obolibrary.org/obo/GO_0035352 GO:0098953 biolink:BiologicalProcess receptor diffusion trapping The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0098953 GO:1902579 biolink:BiologicalProcess multi-organism localization A localization which involves another organism. go-plus.json multi organism localization http://purl.obolibrary.org/obo/GO_1902579 GO:0060390 biolink:BiologicalProcess regulation of SMAD protein signal transduction Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. go-plus.json regulation of SMAD protein nuclear translocation|SMAD protein import into nucleus http://purl.obolibrary.org/obo/GO_0060390 GO:1902577 biolink:BiologicalProcess protein localization to medial cortical node A process in which a protein is transported to, or maintained in, a location within a medial cortical node. go-plus.json protein localisation to medial cortical node|protein localisation in medial cortical node|protein localization in medial cortical node http://purl.obolibrary.org/obo/GO_1902577 GO:0060391 biolink:BiologicalProcess positive regulation of SMAD protein signal transduction Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. go-plus.json positive regulation of SMAD protein nuclear translocation|positive regulation of SMAD protein import into nucleus http://purl.obolibrary.org/obo/GO_0060391 GO:0060392 biolink:BiologicalProcess negative regulation of SMAD protein signal transduction Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. go-plus.json negative regulation of SMAD protein nuclear translocation|negative regulation of SMAD protein import into nucleus http://purl.obolibrary.org/obo/GO_0060392 GO:1902578 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902578 GO:1902575 biolink:BiologicalProcess protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly. go-plus.json protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring assembly|protein localisation to cell division site involved in constriction ring assembly|protein localization to cell division site involved in contractile ring assembly|protein localization to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in cytokinesis, contractile ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localization to cell division site involved in cytokinesis, actomyosin ring formation|protein localization to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localization to cell division site involved in constriction ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin ring formation|protein localisation to cell division site involved in contractile ring assembly|protein localization to cell division site involved in cytokinesis, contractile ring assembly http://purl.obolibrary.org/obo/GO_1902575 GO:0060393 biolink:BiologicalProcess regulation of pathway-restricted SMAD protein phosphorylation Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0060393 GO:1902576 biolink:BiologicalProcess negative regulation of nuclear cell cycle DNA replication Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication. go-plus.json down regulation of DNA replication involved in S phase|inhibition of DNA replication involved in S-phase|downregulation of DNA replication during S phase|downregulation of DNA replication involved in S phase|downregulation of nuclear cell cycle DNA replication|down regulation of DNA replication during S phase|down regulation of nuclear cell cycle DNA replication|inhibition of nuclear cell cycle DNA replication|down-regulation of DNA replication involved in S phase|inhibition of DNA replication during S phase|negative regulation of DNA replication involved in S phase|down regulation of DNA replication involved in S-phase|downregulation of DNA replication involved in S-phase|inhibition of DNA replication involved in S phase|negative regulation of DNA replication during S phase|down-regulation of DNA replication during S phase|down-regulation of DNA replication involved in S-phase|negative regulation of DNA replication involved in S-phase|down-regulation of nuclear cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902576 GO:0060394 biolink:BiologicalProcess negative regulation of pathway-restricted SMAD protein phosphorylation Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0060394 GO:1902573 biolink:BiologicalProcess positive regulation of serine-type peptidase activity Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity. go-plus.json activation of serine protease activity|positive regulation of serine protease activity|up regulation of serine protease activity|upregulation of serine-type peptidase activity|up-regulation of serine-type peptidase activity|upregulation of serine protease activity|activation of serine-type peptidase activity|up-regulation of serine protease activity|up regulation of serine-type peptidase activity http://purl.obolibrary.org/obo/GO_1902573 GO:0060395 biolink:BiologicalProcess SMAD protein signal transduction The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0060395 GO:1902574 biolink:BiologicalProcess obsolete negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of leucine import. go-plus.json http://purl.obolibrary.org/obo/GO_1902574 GO:0060396 biolink:BiologicalProcess growth hormone receptor signaling pathway The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. go-plus.json growth hormone receptor signalling pathway|cellular response to growth hormone|GH receptor signaling pathway http://purl.obolibrary.org/obo/GO_0060396 GO:0035342 biolink:BiologicalProcess positive regulation of inosine transport Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json positive regulation of hypoxanthine riboside transport http://purl.obolibrary.org/obo/GO_0035342 GO:0060397 biolink:BiologicalProcess growth hormone receptor signaling pathway via JAK-STAT The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. go-plus.json JAK-STAT cascade involved in growth hormone signalling pathway http://purl.obolibrary.org/obo/GO_0060397 GO:1902582 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902582 GO:1902583 biolink:BiologicalProcess obsolete multi-organism intracellular transport OBSOLETE. An intracellular transport which involves another organism. go-plus.json multi organism intracellular transport http://purl.obolibrary.org/obo/GO_1902583 GO:0035343 biolink:BiologicalProcess negative regulation of inosine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json negative regulation of hypoxanthine riboside transport http://purl.obolibrary.org/obo/GO_0035343 GO:0060398 biolink:BiologicalProcess regulation of growth hormone receptor signaling pathway Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. go-plus.json regulation of growth hormone receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060398 GO:0060399 biolink:BiologicalProcess positive regulation of growth hormone receptor signaling pathway Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. go-plus.json positive regulation of growth hormone receptor signalling pathway http://purl.obolibrary.org/obo/GO_0060399 GO:0035344 biolink:BiologicalProcess hypoxanthine transport The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json hypoxanthine transmembrane transport|6-hydroxypurine transport http://purl.obolibrary.org/obo/GO_0035344 GO:1902580 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902580 GO:0035345 biolink:BiologicalProcess regulation of hypoxanthine transport Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of 6-hydroxypurine transport http://purl.obolibrary.org/obo/GO_0035345 GO:1902581 biolink:BiologicalProcess multi-organism cellular localization A cellular localization which involves another organism. go-plus.json multi organism cellular localization http://purl.obolibrary.org/obo/GO_1902581 GO:0035346 biolink:BiologicalProcess positive regulation of hypoxanthine transport Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json positive regulation of 6-hydroxypurine transport http://purl.obolibrary.org/obo/GO_0035346 GO:0035347 biolink:BiologicalProcess negative regulation of hypoxanthine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json negative regulation of 6-hydroxypurine transport http://purl.obolibrary.org/obo/GO_0035347 GO:0035348 biolink:BiologicalProcess acetyl-CoA transmembrane transport The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. go-plus.json acetyl-CoA membrane transport http://purl.obolibrary.org/obo/GO_0035348 GO:0035349 biolink:BiologicalProcess coenzyme A transmembrane transport The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. go-plus.json coenzyme A membrane transport http://purl.obolibrary.org/obo/GO_0035349 GO:0035340 biolink:BiologicalProcess inosine transport The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json hypoxanthine riboside transport http://purl.obolibrary.org/obo/GO_0035340 GO:0035341 biolink:BiologicalProcess regulation of inosine transport Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of hypoxanthine riboside transport http://purl.obolibrary.org/obo/GO_0035341 GO:0035339 biolink:CellularComponent SPOTS complex A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis. go-plus.json serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex http://purl.obolibrary.org/obo/GO_0035339 GO:1902588 biolink:BiologicalProcess obsolete multi-organism plasmodesmata-mediated intercellular transport OBSOLETE. A plasmodesmata-mediated intercellular transport which involves another organism. go-plus.json multi organism plasmodesmata-mediated intercellular transport http://purl.obolibrary.org/obo/GO_1902588 GO:0060380 biolink:BiologicalProcess regulation of single-stranded telomeric DNA binding Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA. go-plus.json regulation of telomeric ssDNA binding http://purl.obolibrary.org/obo/GO_0060380 GO:1902589 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902589 GO:0060381 biolink:BiologicalProcess positive regulation of single-stranded telomeric DNA binding Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding. go-plus.json positive regulation of telomeric ssDNA binding http://purl.obolibrary.org/obo/GO_0060381 GO:1902586 biolink:BiologicalProcess multi-organism intercellular transport An intercellular transport which involves another organism. go-plus.json multi organism intercellular transport http://purl.obolibrary.org/obo/GO_1902586 GO:0060382 biolink:BiologicalProcess regulation of DNA strand elongation Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. go-plus.json http://purl.obolibrary.org/obo/GO_0060382 GO:1902587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902587 GO:0060383 biolink:BiologicalProcess positive regulation of DNA strand elongation Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. go-plus.json http://purl.obolibrary.org/obo/GO_0060383 GO:1902584 biolink:BiologicalProcess positive regulation of response to water deprivation Any process that activates or increases the frequency, rate or extent of response to water deprivation. go-plus.json positive regulation of drought tolerance|upregulation of response to drought|up-regulation of response to dehydration|up-regulation of response to thirst|activation of drought tolerance|activation of response to thirst|upregulation of response to water deprivation|up-regulation of drought tolerance|up regulation of response to drought|upregulation of response to dehydration|activation of response to drought|positive regulation of response to drought|up regulation of response to water deprivation|positive regulation of response to thirst|activation of response to water deprivation|up regulation of response to thirst|upregulation of drought tolerance|up regulation of response to dehydration|activation of response to dehydration|positive regulation of response to dehydration|up-regulation of response to drought|upregulation of response to thirst|up-regulation of response to water deprivation|up regulation of drought tolerance http://purl.obolibrary.org/obo/GO_1902584 GO:0060384 biolink:BiologicalProcess innervation The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060384 GO:1902585 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902585 GO:0060385 biolink:BiologicalProcess axonogenesis involved in innervation The neurite development process that generates a long process of a neuron, as it invades a target tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0060385 GO:0035331 biolink:BiologicalProcess negative regulation of hippo signaling Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling. go-plus.json negative regulation of hippo signaling cascade|negative regulation of hippo signalling cascade|negative regulation of hippo signaling pathway http://purl.obolibrary.org/obo/GO_0035331 GO:1902593 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902593 GO:0060386 biolink:BiologicalProcess synapse assembly involved in innervation The assembly of a synapse within a target tissue in which a nerve is invading. go-plus.json synapse biogenesis involved in innervation|synaptogenesis involved in innervation http://purl.obolibrary.org/obo/GO_0060386 GO:0035332 biolink:BiologicalProcess positive regulation of hippo signaling Any process that activates or increases the frequency, rate or extent of hippo signaling. go-plus.json positive regulation of hippo signaling pathway|positive regulation of hippo signalling cascade|positive regulation of hippo signaling cascade http://purl.obolibrary.org/obo/GO_0035332 GO:1902594 biolink:BiologicalProcess multi-organism nuclear import A nuclear import which involves another organism. go-plus.json multi organism nuclear import http://purl.obolibrary.org/obo/GO_1902594 GO:0060387 biolink:CellularComponent fertilization envelope A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release. go-plus.json fertilization membrane http://purl.obolibrary.org/obo/GO_0060387 GO:0035333 biolink:BiologicalProcess Notch receptor processing, ligand-dependent The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD). go-plus.json Notch S2 cleavage|Notch S3 cleavage http://purl.obolibrary.org/obo/GO_0035333 GO:1902591 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902591 GO:0060388 biolink:CellularComponent vitelline envelope A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization. go-plus.json fertilization membrane http://purl.obolibrary.org/obo/GO_0060388 GO:1902592 biolink:BiologicalProcess obsolete multi-organism membrane budding OBSOLETE. A membrane budding which involves another organism. go-plus.json multi organism membrane budding http://purl.obolibrary.org/obo/GO_1902592 GO:0060389 biolink:BiologicalProcess pathway-restricted SMAD protein phosphorylation The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor. go-plus.json R-SMAD protein phosphorylation|receptor-regulated SMAD protein phosphorylation|pathway restricted SMAD protein phosphorylation|receptor regulated SMAD protein phosphorylation http://purl.obolibrary.org/obo/GO_0060389 GO:0035334 biolink:BiologicalProcess Notch receptor processing, ligand-independent The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface. go-plus.json Notch S1 cleavage http://purl.obolibrary.org/obo/GO_0035334 GO:0035335 biolink:BiologicalProcess peptidyl-tyrosine dephosphorylation The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. go-plus.json http://purl.obolibrary.org/obo/GO_0035335 GO:0035336 biolink:BiologicalProcess long-chain fatty-acyl-CoA metabolic process The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. go-plus.json long-chain fatty acyl CoA metabolic process|long-chain fatty acyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0035336 GO:1902590 biolink:BiologicalProcess multi-organism organelle organization An organelle organization which involves another organism. go-plus.json multi organism organelle organization http://purl.obolibrary.org/obo/GO_1902590 GO:0035337 biolink:BiologicalProcess fatty-acyl-CoA metabolic process The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. go-plus.json fatty acyl CoA metabolic process|fatty-acyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0035337 GO:0035338 biolink:BiologicalProcess long-chain fatty-acyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. go-plus.json long-chain fatty-acyl-CoA anabolism|long-chain fatty-acyl-CoA synthesis|long-chain fatty acyl CoA biosynthetic process|long-chain fatty-acyl-CoA biosynthesis|long-chain fatty-acyl-CoA formation http://purl.obolibrary.org/obo/GO_0035338 GO:0035330 biolink:BiologicalProcess regulation of hippo signaling Any process that modulates the frequency, rate or extent of hippo signaling. go-plus.json regulation of hippo signalling cascade|regulation of hippo signaling pathway|regulation of hippo signaling cascade http://purl.obolibrary.org/obo/GO_0035330 GO:0098983 biolink:CellularComponent symmetric, GABA-ergic, inhibitory synapse A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials. go-plus.json http://purl.obolibrary.org/obo/GO_0098983 GO:0098984 biolink:CellularComponent neuron to neuron synapse A synapse in which pre and post-synaptic cells are neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0098984 GO:0098981 biolink:CellularComponent cholinergic synapse A synapse that uses acetylcholine as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0098981 goslim_synapse GO:0098982 biolink:CellularComponent GABA-ergic synapse A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory. go-plus.json http://purl.obolibrary.org/obo/GO_0098982 goslim_synapse GO:0098980 biolink:CellularComponent presynaptic density An electron dense specialization of the presynaptic active zone cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0098980 GO:0035328 biolink:CellularComponent transcriptionally silent chromatin The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed. go-plus.json transcriptionally inactive chromatin http://purl.obolibrary.org/obo/GO_0035328 GO:0035329 biolink:BiologicalProcess hippo signaling The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. go-plus.json Salvador-Warts-Hippo signaling pathway|hippo signalling cascade|hippo signal transduction|SWH pathway|hippo signaling pathway|hippo signaling cascade http://purl.obolibrary.org/obo/GO_0035329 GO:1902599 biolink:BiologicalProcess sulfathiazole transmembrane transport The directed movement of sulfathiazole across a membrane. go-plus.json sulfathiazole transport|sulphathiazole transport http://purl.obolibrary.org/obo/GO_1902599 GO:1902597 biolink:BiologicalProcess positive regulation of DNA replication origin binding Any process that activates or increases the frequency, rate or extent of DNA replication origin binding. go-plus.json upregulation of DNA replication origin binding|up regulation of ARS binding|positive regulation of ARS binding|activation of ARS binding|up-regulation of DNA replication origin binding|activation of DNA replication origin binding|up-regulation of ARS binding|up regulation of DNA replication origin binding|upregulation of ARS binding http://purl.obolibrary.org/obo/GO_1902597 GO:1902598 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902598 GO:1902595 biolink:BiologicalProcess regulation of DNA replication origin binding Any process that modulates the frequency, rate or extent of DNA replication origin binding. go-plus.json regulation of ARS binding http://purl.obolibrary.org/obo/GO_1902595 GO:1902596 biolink:BiologicalProcess negative regulation of DNA replication origin binding Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding. go-plus.json down regulation of ARS binding|down regulation of DNA replication origin binding|downregulation of ARS binding|inhibition of DNA replication origin binding|negative regulation of ARS binding|down-regulation of ARS binding|down-regulation of DNA replication origin binding|inhibition of ARS binding|downregulation of DNA replication origin binding http://purl.obolibrary.org/obo/GO_1902596 GO:0035320 biolink:BiologicalProcess imaginal disc-derived wing hair site selection Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally. go-plus.json wing hair site selection|prehair localization http://purl.obolibrary.org/obo/GO_0035320 GO:0035321 biolink:BiologicalProcess maintenance of imaginal disc-derived wing hair orientation Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity. go-plus.json maintenance of wing hair orientation http://purl.obolibrary.org/obo/GO_0035321 GO:0035322 biolink:BiologicalProcess mesenchymal cell migration involved in limb bud formation The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud. go-plus.json http://purl.obolibrary.org/obo/GO_0035322 GO:0035323 biolink:CellularComponent male germline ring canal An intercellular bridge that connects the germline cells of a male cyst. go-plus.json testicular ring canal|spermatocyte ring canal http://purl.obolibrary.org/obo/GO_0035323 GO:0035324 biolink:CellularComponent female germline ring canal An intercellular bridge that connects the germline cells of a female cyst. go-plus.json ovarian ring canal|nurse cell ring canal http://purl.obolibrary.org/obo/GO_0035324 GO:0035325 biolink:MolecularActivity Toll-like receptor binding Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. go-plus.json TLR binding http://purl.obolibrary.org/obo/GO_0035325 GO:0035326 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035326 GO:0035327 biolink:CellularComponent transcriptionally active chromatin The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed. go-plus.json http://purl.obolibrary.org/obo/GO_0035327 CHEBI:37296 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37296 GO:0098989 biolink:BiologicalProcess NMDA selective glutamate receptor signaling pathway A series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0098989 CHEBI:37293 biolink:ChemicalSubstance 1-ribosylimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_37293 GO:0098987 biolink:BiologicalProcess regulation of modification of synapse structure, modulating synaptic transmission Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0098987 goslim_synapse GO:0098988 biolink:MolecularActivity G protein-coupled glutamate receptor activity Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. go-plus.json G-protein coupled glutamate receptor activity http://purl.obolibrary.org/obo/GO_0098988 GO:0098985 biolink:CellularComponent asymmetric, glutamatergic, excitatory synapse A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials. go-plus.json http://purl.obolibrary.org/obo/GO_0098985 GO:0098986 biolink:CellularComponent T-bar A T-shaped presynpatic density. These are common in arhropod central nervous systems. go-plus.json http://purl.obolibrary.org/obo/GO_0098986 GO:0098994 biolink:BiologicalProcess disruption of host cell envelope during viral entry The disruption of host cell envelope by viral proteins during virus entry. VZ:3938 go-plus.json http://purl.obolibrary.org/obo/GO_0098994 GO:0098995 biolink:BiologicalProcess disruption by virus of host envelope lipopolysaccharide during virus entry The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides. VZ:3939 go-plus.json disassembly by virus of outer membrane lipopolysaccharide during viral entry|degradation of host cell envelope lipopolysaccharide during viral entry|degradation of host lipopolysaccharide during virus entry http://purl.obolibrary.org/obo/GO_0098995 GO:0098992 biolink:CellularComponent neuronal dense core vesicle A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. go-plus.json http://purl.obolibrary.org/obo/GO_0098992 goslim_synapse GO:0098993 biolink:CellularComponent anchored component of synaptic vesicle membrane The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json http://purl.obolibrary.org/obo/GO_0098993 goslim_synapse GO:0098990 biolink:BiologicalProcess AMPA selective glutamate receptor signaling pathway A series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0098990 goslim_synapse GO:0098991 biolink:BiologicalProcess kainate selective glutamate receptor signaling pathway A series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0098991 goslim_synapse CHEBI:144644 biolink:ChemicalSubstance a tetracycline zwittterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_144644 chebi_ph7_3 CHEBI:144645 biolink:ChemicalSubstance an 11a-hydroxytetracyline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_144645 chebi_ph7_3 GO:0035317 biolink:BiologicalProcess imaginal disc-derived wing hair organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster. go-plus.json imaginal disc-derived wing hair organization and biogenesis|wing hair organization and biogenesis|wing hair organisation|wing trichome organization and biogenesis http://purl.obolibrary.org/obo/GO_0035317 GO:0035318 biolink:BiologicalProcess imaginal disc-derived wing hair outgrowth Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair. go-plus.json wing hair outgrowth|wing prehair outgrowth http://purl.obolibrary.org/obo/GO_0035318 GO:0035319 biolink:BiologicalProcess imaginal disc-derived wing hair elongation Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles. go-plus.json wing prehair extension|wing hair elongation http://purl.obolibrary.org/obo/GO_0035319 GO:0035310 biolink:BiologicalProcess notum cell fate specification The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment. go-plus.json http://purl.obolibrary.org/obo/GO_0035310 GO:0035311 biolink:BiologicalProcess wing cell fate specification The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment. go-plus.json http://purl.obolibrary.org/obo/GO_0035311 GO:0035312 biolink:MolecularActivity 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0035312 GO:0035313 biolink:BiologicalProcess wound healing, spreading of epidermal cells The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0035313 GO:0035314 biolink:BiologicalProcess scab formation Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection. go-plus.json http://purl.obolibrary.org/obo/GO_0035314 GO:0035315 biolink:BiologicalProcess hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hair cell. go-plus.json http://purl.obolibrary.org/obo/GO_0035315 GO:0035316 biolink:BiologicalProcess non-sensory hair organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis. go-plus.json trichome organisation|non-sensory hair organization and biogenesis|trichome organization and biogenesis http://purl.obolibrary.org/obo/GO_0035316 GO:0098998 biolink:CellularComponent extrinsic component of postsynaptic early endosome membrane The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098998 goslim_synapse GO:0098999 biolink:CellularComponent extrinsic component of postsynaptic endosome membrane The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098999 goslim_synapse GO:0098996 biolink:BiologicalProcess disruption of host cell glycocalyx during viral entry The disruption of host cell glycocalyx by viral proteins during virus entry. VZ:3938 go-plus.json disassembly of glycocalyx during viral entry|catabolism of host glycocalyx during viral entry|degradation of host glycocalyx during viral entry|degradation of host capsule during virus entry http://purl.obolibrary.org/obo/GO_0098996 GO:0098997 biolink:BiologicalProcess fusion of virus membrane with host outer membrane Fusion of a viral membrane with the host cell outer membrane during viral entry. VZ:3941 go-plus.json viral envelope fusion with host outer membrane|viral envelope fusion|viral penetration via membrane fusion|fusion of viral membrane with host outer membrane|viral-cell fusion molecule activity http://purl.obolibrary.org/obo/GO_0098997 CHEBI:76889 biolink:ChemicalSubstance (9Z,12Z)-hexadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76889 CHEBI:27911 biolink:ChemicalSubstance N(8)-acetylspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27911 GO:0050940 biolink:BiologicalProcess regulation of late stripe melanocyte differentiation Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation. go-plus.json regulation of late stripe melanophore differentiation http://purl.obolibrary.org/obo/GO_0050940 CHEBI:27913 biolink:ChemicalSubstance L-erythrulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27913 chebi_ph7_3 CHEBI:27914 biolink:ChemicalSubstance hydrogenobyrinic acid a,c-diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27914 GO:0050943 biolink:BiologicalProcess negative regulation of iridophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation. go-plus.json downregulation of iridophore differentiation|down regulation of iridophore differentiation|inhibition of iridophore differentiation|down-regulation of iridophore differentiation http://purl.obolibrary.org/obo/GO_0050943 GO:0050944 biolink:BiologicalProcess negative regulation of xanthophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation. go-plus.json down-regulation of xanthophore differentiation|inhibition of xanthophore differentiation|down regulation of xanthophore differentiation|downregulation of xanthophore differentiation http://purl.obolibrary.org/obo/GO_0050944 GO:0050941 biolink:BiologicalProcess negative regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. go-plus.json down-regulation of pigment cell differentiation|downregulation of pigment cell differentiation|down regulation of pigment cell differentiation|inhibition of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050941 GO:0050942 biolink:BiologicalProcess positive regulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. go-plus.json up-regulation of pigment cell differentiation|activation of pigment cell differentiation|up regulation of pigment cell differentiation|upregulation of pigment cell differentiation|stimulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050942 CHEBI:27910 biolink:ChemicalSubstance 7-dehydrodesmosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27910 chebi_ph7_3 GO:0050947 biolink:BiologicalProcess negative regulation of early stripe melanocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation. go-plus.json down regulation of early stripe melanocyte differentiation|downregulation of early stripe melanocyte differentiation|down-regulation of early stripe melanocyte differentiation|inhibition of early stripe melanocyte differentiation|negative regulation of early stripe melanophore differentiation http://purl.obolibrary.org/obo/GO_0050947 GO:0050948 biolink:BiologicalProcess positive regulation of early stripe melanocyte differentiation Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation. go-plus.json upregulation of early stripe melanocyte differentiation|up regulation of early stripe melanocyte differentiation|activation of early stripe melanocyte differentiation|stimulation of early stripe melanocyte differentiation|up-regulation of early stripe melanocyte differentiation|positive regulation of early stripe melanophore differentiation http://purl.obolibrary.org/obo/GO_0050948 CHEBI:62241 biolink:ChemicalSubstance UDP-N-acetyl-beta-L-fucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62241 chebi_ph7_3 GO:0050945 biolink:BiologicalProcess positive regulation of iridophore differentiation Any process that activates or increases the frequency, rate or extent of iridophore differentiation. go-plus.json up regulation of iridophore differentiation|upregulation of iridophore differentiation|stimulation of iridophore differentiation|up-regulation of iridophore differentiation|activation of iridophore differentiation http://purl.obolibrary.org/obo/GO_0050945 GO:0050946 biolink:BiologicalProcess positive regulation of xanthophore differentiation Any process that activates or increases the frequency, rate or extent of xanthophore differentiation. go-plus.json up regulation of xanthophore differentiation|activation of xanthophore differentiation|stimulation of xanthophore differentiation|up-regulation of xanthophore differentiation|upregulation of xanthophore differentiation http://purl.obolibrary.org/obo/GO_0050946 CHEBI:62244 biolink:ChemicalSubstance trans,trans-deca-2,4-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62244 chebi_ph7_3 CHEBI:62245 biolink:ChemicalSubstance UDP-2-acetamido-3-ammonio-2,3-dideoxy-alpha-D-glucuronate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62245 chebi_ph7_3 GO:0050949 biolink:BiologicalProcess negative regulation of late stripe melanocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation. go-plus.json down regulation of late stripe melanocyte differentiation|inhibition of late stripe melanocyte differentiation|down-regulation of late stripe melanocyte differentiation|negative regulation of late stripe melanophore differentiation|downregulation of late stripe melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050949 CHEBI:62242 biolink:ChemicalSubstance trans-oct-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62242 chebi_ph7_3 CHEBI:62243 biolink:ChemicalSubstance trans,trans-octa-2,4-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62243 chebi_ph7_3 GO:2001152 biolink:BiologicalProcess negative regulation of renal water transport Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001152 CHEBI:62248 biolink:ChemicalSubstance phenazine-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62248 chebi_ph7_3 GO:2001153 biolink:BiologicalProcess positive regulation of renal water transport Any process that activates or increases the frequency, rate or extent of renal water transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001153 GO:2001154 biolink:BiologicalProcess regulation of glycolytic fermentation to ethanol Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol. go-plus.json regulation of glucose fermentation to ethanol|regulation of ethanol fermentation http://purl.obolibrary.org/obo/GO_2001154 CHEBI:62246 biolink:ChemicalSubstance (S)-2-hydroxypropylphosphonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62246 chebi_ph7_3 CHEBI:62247 biolink:ChemicalSubstance (1R,2S)-epoxypropylphosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62247 chebi_ph7_3 GO:2001155 biolink:BiologicalProcess negative regulation of glycolytic fermentation to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol. go-plus.json negative regulation of glucose fermentation to ethanol|negative regulation of ethanol fermentation http://purl.obolibrary.org/obo/GO_2001155 GO:2001156 biolink:BiologicalProcess regulation of proline catabolic process to glutamate Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate. go-plus.json regulation of proline oxidation|regulation of proline breakdown to glutamate|regulation of proline degradation to glutamate http://purl.obolibrary.org/obo/GO_2001156 GO:2001157 biolink:BiologicalProcess negative regulation of proline catabolic process to glutamate Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate. go-plus.json negative regulation of proline breakdown to glutamate|negative regulation of proline degradation to glutamate|negative regulation of proline oxidation http://purl.obolibrary.org/obo/GO_2001157 GO:2001158 biolink:BiologicalProcess positive regulation of proline catabolic process to glutamate Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate. go-plus.json positive regulation of proline breakdown to glutamate|positive regulation of proline oxidation|positive regulation of proline degradation to glutamate http://purl.obolibrary.org/obo/GO_2001158 GO:2001159 biolink:BiologicalProcess regulation of protein localization by the Cvt pathway Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway. go-plus.json regulation of cytoplasm to vacuole targeting|regulation of cytoplasm-to-vacuole targeting http://purl.obolibrary.org/obo/GO_2001159 CHEBI:76881 biolink:ChemicalSubstance EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76881 CHEBI:76882 biolink:ChemicalSubstance EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76882 CHEBI:76885 biolink:ChemicalSubstance EC 3.4.23.* (aspartic endopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76885 CHEBI:27915 biolink:ChemicalSubstance melamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27915 GO:2001150 biolink:BiologicalProcess positive regulation of dipeptide transmembrane transport Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport. go-plus.json positive regulation of dipeptide membrane transport http://purl.obolibrary.org/obo/GO_2001150 CHEBI:76883 biolink:ChemicalSubstance EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76883 GO:2001151 biolink:BiologicalProcess regulation of renal water transport Any process that modulates the frequency, rate or extent of renal water transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001151 GO:0050950 biolink:BiologicalProcess positive regulation of late stripe melanocyte differentiation Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation. go-plus.json positive regulation of late stripe melanophore differentiation|up regulation of late stripe melanocyte differentiation|upregulation of late stripe melanocyte differentiation|stimulation of late stripe melanocyte differentiation|activation of late stripe melanocyte differentiation|up-regulation of late stripe melanocyte differentiation http://purl.obolibrary.org/obo/GO_0050950 CHEBI:27922 biolink:ChemicalSubstance sorbose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27922 GO:0050951 biolink:BiologicalProcess sensory perception of temperature stimulus The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json sensory perception of thermal stimulus http://purl.obolibrary.org/obo/GO_0050951 CHEBI:76898 biolink:ChemicalSubstance EC 1.14.14.1 (unspecific monooxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76898 GO:0050954 biolink:BiologicalProcess sensory perception of mechanical stimulus The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json mechanosensory perception|perception of mechanical stimulus|chemi-mechanical coupling http://purl.obolibrary.org/obo/GO_0050954 GO:0050955 biolink:BiologicalProcess thermoception The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature). Wikipedia:Thermoception go-plus.json thermoreception http://purl.obolibrary.org/obo/GO_0050955 GO:0050952 biolink:BiologicalProcess sensory perception of electrical stimulus The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json http://purl.obolibrary.org/obo/GO_0050952 GO:0050953 biolink:BiologicalProcess sensory perception of light stimulus The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json http://purl.obolibrary.org/obo/GO_0050953 GO:0050958 biolink:BiologicalProcess magnetoreception The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light. Wikipedia:Magnetoception go-plus.json sensory perception of magnetic field|magnetoception http://purl.obolibrary.org/obo/GO_0050958 CHEBI:62251 biolink:ChemicalSubstance 2-(beta-D-glucosyloxy)-cis-cinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62251 GO:0050959 biolink:BiologicalProcess echolocation Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning. Wikipedia:Echolocation go-plus.json perception of environment using reflected sound waves|biological sonar http://purl.obolibrary.org/obo/GO_0050959 GO:0050956 biolink:BiologicalProcess electroception The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location. Wikipedia:Electroreception go-plus.json electroception sense|electroceptive sense http://purl.obolibrary.org/obo/GO_0050956 GO:0050957 biolink:BiologicalProcess equilibrioception The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion. Wikipedia:Equilibrioception go-plus.json sensory perception of orientation with respect to gravity http://purl.obolibrary.org/obo/GO_0050957 CHEBI:62250 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62250 chebi_ph7_3 CHEBI:62254 biolink:ChemicalSubstance GDP-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62254 CHEBI:62259 biolink:ChemicalSubstance alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_62259 chebi_ph7_3 GO:2001163 biolink:BiologicalProcess regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues. go-plus.json http://purl.obolibrary.org/obo/GO_2001163 GO:2001164 biolink:BiologicalProcess negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues. go-plus.json http://purl.obolibrary.org/obo/GO_2001164 GO:2001165 biolink:BiologicalProcess positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues. go-plus.json http://purl.obolibrary.org/obo/GO_2001165 GO:2001166 biolink:BiologicalProcess regulation of histone H2B ubiquitination Any process that modulates the frequency, rate or extent of histone H2B ubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_2001166 GO:2001167 biolink:BiologicalProcess negative regulation of histone H2B ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B ubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_2001167 GO:2001168 biolink:BiologicalProcess positive regulation of histone H2B ubiquitination Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_2001168 GO:2001169 biolink:BiologicalProcess regulation of ATP biosynthetic process Any process that modulates the frequency, rate or extent of ATP biosynthetic process. go-plus.json regulation of ATP biosynthesis|regulation of ATP anabolism|regulation of ATP synthesis|regulation of ATP regeneration|regulation of ATP formation http://purl.obolibrary.org/obo/GO_2001169 CHEBI:76892 biolink:ChemicalSubstance A47934(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76892 chebi_ph7_3 CHEBI:76893 biolink:ChemicalSubstance EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76893 CHEBI:76891 biolink:ChemicalSubstance EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76891 CHEBI:27926 biolink:ChemicalSubstance beta-D-xyloside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27926 CHEBI:76896 biolink:ChemicalSubstance (11Z)-3-oxooctadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76896 GO:2001160 biolink:BiologicalProcess regulation of histone H3-K79 methylation Any process that modulates the frequency, rate or extent of histone H3-K79 methylation. go-plus.json regulation of histone lysine H3 K79 methylation|regulation of histone H3 K79 methylation|regulation of histone H3K79me http://purl.obolibrary.org/obo/GO_2001160 GO:2001161 biolink:BiologicalProcess negative regulation of histone H3-K79 methylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 methylation. go-plus.json negative regulation of histone H3K79me|negative regulation of histone lysine H3 K79 methylation|negative regulation of histone H3 K79 methylation http://purl.obolibrary.org/obo/GO_2001161 CHEBI:27928 biolink:ChemicalSubstance parathion go-plus.json http://purl.obolibrary.org/obo/CHEBI_27928 chebi_ph7_3 CHEBI:76894 biolink:ChemicalSubstance A41030A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76894 chebi_ph7_3 GO:2001162 biolink:BiologicalProcess positive regulation of histone H3-K79 methylation Any process that activates or increases the frequency, rate or extent of histone H3-K79 methylation. go-plus.json positive regulation of histone H3K79me|positive regulation of histone H3 K79 methylation|positive regulation of histone lysine H3 K79 methylation http://purl.obolibrary.org/obo/GO_2001162 CHEBI:76895 biolink:ChemicalSubstance EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_76895 GO:0050961 biolink:BiologicalProcess detection of temperature stimulus involved in sensory perception The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception. go-plus.json sensory perception, sensory detection of heat stimulus|sensory perception, sensory detection of temperature stimulus|sensory detection of temperature stimulus during sensory perception|sensory perception, sensory detection of thermal stimulus|sensory detection of thermal stimulus during sensory perception|sensory detection of temperature stimulus|sensory transduction of temperature stimulus during sensory perception|sensory transduction of thermal stimulus during sensory perception|sensory transduction of temperature stimulus|sensory perception, sensory transduction of heat stimulus|sensory transduction of heat stimulus during sensory perception|sensory perception, sensory transduction of temperature stimulus|sensory detection of heat stimulus during sensory perception|sensory perception, sensory transduction of thermal stimulus http://purl.obolibrary.org/obo/GO_0050961 GO:0050962 biolink:BiologicalProcess detection of light stimulus involved in sensory perception The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. go-plus.json sensory perception, sensory detection of light stimulus|sensory detection of light stimulus during sensory perception|sensory detection of light stimulus|sensory transduction of light stimulus during sensory perception|sensory transduction of light stimulus|sensory perception, sensory transduction of light stimulus http://purl.obolibrary.org/obo/GO_0050962 GO:0050960 biolink:BiologicalProcess detection of temperature stimulus involved in thermoception The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception. go-plus.json sensory transduction of thermal stimulus during thermoception|sensory transduction of temperature stimulus during thermoception|sensory detection of thermal stimulus during thermoception|sensory detection of temperature stimulus during thermoception|thermoception, sensory transduction of temperature stimulus|thermoception, sensory detection of temperature stimulus|thermoception, sensory transduction of thermal stimulus|thermoception, sensory detection of thermal stimulus http://purl.obolibrary.org/obo/GO_0050960 GO:0050965 biolink:BiologicalProcess detection of temperature stimulus involved in sensory perception of pain The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal. go-plus.json thermal nociception|perception of pain, detection of temperature stimulus|perception of pain, sensory detection of temperature stimulus|sensory perception of pain, sensory detection of thermal stimulus|sensory detection of temperature stimulus during perception of pain|sensory detection of thermal stimulus during sensory perception of pain|sensory transduction of temperature stimulus during perception of pain|sensory transduction of thermal stimulus during sensory perception of pain|perception of pain, sensory transduction of temperature stimulus|sensory perception of pain, sensory transduction of thermal stimulus http://purl.obolibrary.org/obo/GO_0050965 GO:0050966 biolink:BiologicalProcess detection of mechanical stimulus involved in sensory perception of pain The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal. go-plus.json perception of pain, sensory detection of mechanical stimulus|mechanical nociception|perception of pain, detection of mechanical stimulus|perception of pain, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during perception of pain|sensory detection of mechanical stimulus during perception of pain http://purl.obolibrary.org/obo/GO_0050966 PO:0000225 biolink:OntologyClass peripheral zone A portion of meristem tissue (PO:0009013) which is the organogenic region of the meristem, characterized by higher rates of cell division. go-plus.json zona periférica (Spanish, exact)|peripheral meristem (related)|周辺帯 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000225 GO:0050963 biolink:BiologicalProcess detection of electrical stimulus involved in sensory perception The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception. go-plus.json sensory perception, sensory transduction of electrical stimulus|sensory transduction of electrical stimulus during sensory perception|sensory detection of electrical stimulus during sensory perception|sensory transduction of electrical stimulus|sensory detection of electrical stimulus|sensory perception, sensory detection of electrical stimulus http://purl.obolibrary.org/obo/GO_0050963 GO:0050964 biolink:BiologicalProcess detection of electrical stimulus involved in electroception The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal. go-plus.json sensory transduction of electrical stimulus during electroception|sensory detection of electrical stimulus during electroception|electroception, sensory detection of electrical stimulus|electroception, detection of electrical stimulus|detection of electrical stimulus during electroreception|electroception, sensory transduction|electroception, sensory transduction of electrical stimulus http://purl.obolibrary.org/obo/GO_0050964 GO:0050969 biolink:BiologicalProcess detection of chemical stimulus involved in magnetoreception The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states. go-plus.json magnetoreception, sensory detection of chemical stimulus|magnetoreception, detection of chemical stimulus|magnetoception, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during magnetoreception|sensory detection of chemical stimulus during magnetoreception|magnetoreception, sensory transduction of chemical stimulus http://purl.obolibrary.org/obo/GO_0050969 CHEBI:62262 biolink:ChemicalSubstance isomultiflorenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62262 chebi_ph7_3 PO:0000229 biolink:OntologyClass flower meristem A portion of reproductive shoot apical meristem tissue (PO:0008028) that gives rise to the floral organs (PO:0025395). go-plus.json mersitema floral (Spanish, exact)|floret meristem (narrow)|Poaceae floret meristem (narrow)|floral apical meristem (related)|tassel floret meristem (narrow)|floral meristem (exact)|ear floret meristem (narrow)|花芽分裂組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000229 CHEBI:62263 biolink:ChemicalSubstance alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_62263 chebi_ph7_3 GO:0050967 biolink:BiologicalProcess detection of electrical stimulus involved in sensory perception of pain The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal. go-plus.json perception of pain, sensory detection of electrical stimulus|perception of pain, detection of electrical stimulus|perception of pain, sensory transduction of electrical stimulus|detection of electrical stimulus during sensory perception of pain|sensory transduction of electrical stimulus during perception of pain|sensory detection of electrical stimulus during perception of pain http://purl.obolibrary.org/obo/GO_0050967 GO:0050968 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of pain The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. go-plus.json sensory detection of chemical stimulus during perception of pain|chemical nociception|perception of pain, sensory detection of chemical stimulus|perception of pain, detection of chemical stimulus|perception of pain, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during perception of pain http://purl.obolibrary.org/obo/GO_0050968 CHEBI:86234 biolink:ChemicalSubstance alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86234 chebi_ph7_3 CHEBI:86236 biolink:ChemicalSubstance alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86236 chebi_ph7_3 CHEBI:62265 biolink:ChemicalSubstance beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_62265 chebi_ph7_3 GO:2001174 biolink:BiologicalProcess negative regulation of histone H2B conserved C-terminal lysine ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination. go-plus.json negative regulation of mammalian H2B K120 ubiquitination|negative regulation of fission yeast H2B K119 ubiquitination|negative regulation of budding yeast H2B K123 ubiquitination http://purl.obolibrary.org/obo/GO_2001174 GO:2001175 biolink:BiologicalProcess positive regulation of histone H2B conserved C-terminal lysine ubiquitination Any process that activates or increases the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination. go-plus.json positive regulation of mammalian H2B K120 ubiquitination|positive regulation of fission yeast H2B K119 ubiquitination|positive regulation of budding yeast H2B K123 ubiquitination http://purl.obolibrary.org/obo/GO_2001175 GO:2001176 biolink:BiologicalProcess regulation of mediator complex assembly Any process that modulates the frequency, rate or extent of mediator complex assembly. go-plus.json http://purl.obolibrary.org/obo/GO_2001176 GO:2001177 biolink:BiologicalProcess negative regulation of mediator complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly. go-plus.json http://purl.obolibrary.org/obo/GO_2001177 GO:2001178 biolink:BiologicalProcess positive regulation of mediator complex assembly Any process that activates or increases the frequency, rate or extent of mediator complex assembly. go-plus.json http://purl.obolibrary.org/obo/GO_2001178 GO:2001179 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001179 GO:2001170 biolink:BiologicalProcess negative regulation of ATP biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. go-plus.json negative regulation of ATP synthesis|negative regulation of ATP formation|negative regulation of ATP biosynthesis|negative regulation of ATP regeneration|negative regulation of ATP anabolism http://purl.obolibrary.org/obo/GO_2001170 GO:2001171 biolink:BiologicalProcess positive regulation of ATP biosynthetic process Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. go-plus.json positive regulation of ATP formation|positive regulation of ATP biosynthesis|positive regulation of ATP regeneration|positive regulation of ATP anabolism|positive regulation of ATP synthesis http://purl.obolibrary.org/obo/GO_2001171 GO:2001172 biolink:BiologicalProcess positive regulation of glycolytic fermentation to ethanol Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol. go-plus.json positive regulation of glucose fermentation to ethanol|positive regulation of ethanol fermentation http://purl.obolibrary.org/obo/GO_2001172 GO:2001173 biolink:BiologicalProcess regulation of histone H2B conserved C-terminal lysine ubiquitination Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination. go-plus.json regulation of fission yeast H2B K119 ubiquitination|regulation of budding yeast H2B K123 ubiquitination|regulation of mammalian H2B K120 ubiquitination http://purl.obolibrary.org/obo/GO_2001173 PO:0000230 biolink:OntologyClass inflorescence meristem A meristem that gives rise to an inflorescence. go-plus.json 花序分裂組織 (Japanese, exact)|meristema de la inflorescencia (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000230 GO:0050972 biolink:BiologicalProcess detection of mechanical stimulus involved in echolocation The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave. go-plus.json echolocation, detection of mechanical stimulus|sensory transduction of mechanical stimulus during echolocation|sensory detection of mechanical stimulus during echolocation|echolocation, sensory transduction of mechanical stimulus|echolocation, sensory detection of mechanical stimulus http://purl.obolibrary.org/obo/GO_0050972 GO:0050973 biolink:BiologicalProcess detection of mechanical stimulus involved in equilibrioception The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears. go-plus.json equilibrioception, sensory detection of mechanical stimulus|equilibrioception, detection of mechanical stimulus|equilibrioception, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during equilibrioception|sensory transduction of mechanical stimulus during equilibrioception http://purl.obolibrary.org/obo/GO_0050973 GO:0050970 biolink:BiologicalProcess detection of electrical stimulus involved in magnetoreception The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field. go-plus.json sensory detection of electrical stimulus during magnetoreception|magnetoreception, sensory detection of electrical stimulus|magnetoreception, detection of electrical stimulus|magnetoception, sensory transduction of electrical stimulus|detection of electrical stimulus during magnetoreception|sensory transduction of electrical stimulus during magnetoreception|magnetoreception, sensory transduction of electrical stimulus http://purl.obolibrary.org/obo/GO_0050970 CHEBI:27902 biolink:ChemicalSubstance tetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_27902 GO:0050971 biolink:BiologicalProcess detection of mechanical stimulus involved in magnetoreception The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field. go-plus.json sensory detection of mechanical stimulus during magnetoreception|magnetoreception, sensory transduction of mechanical stimulus|magnetoreception, sensory detection of mechanical stimulus|magnetoreception, detection of mechanical stimulus|magnetoception, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during magnetoreception http://purl.obolibrary.org/obo/GO_0050971 CHEBI:27903 biolink:ChemicalSubstance (2,4,5-trichlorophenoxy)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27903 GO:0050976 biolink:BiologicalProcess detection of mechanical stimulus involved in sensory perception of touch The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. go-plus.json perception of touch, sensory detection of mechanical stimulus|perception of touch, detection of mechanical stimulus|perception of touch, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during perception of touch|tactition, sensory detection of mechanical stimulus|sensory transduction of mechanical stimulus during perception of touch http://purl.obolibrary.org/obo/GO_0050976 GO:0050977 biolink:BiologicalProcess magnetoreception by sensory perception of chemical stimulus The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli. go-plus.json magnetoreception, sensory perception of chemical stimulus|magnetoreception, using chemical stimulus|magnetoreception through chemical stimulus|magnetoreception by chemical stimulus http://purl.obolibrary.org/obo/GO_0050977 GO:0050974 biolink:BiologicalProcess detection of mechanical stimulus involved in sensory perception The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. go-plus.json sensory perception, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during sensory perception|sensory detection of mechanical stimulus during sensory perception|sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus|sensory perception, sensory detection of mechanical stimulus http://purl.obolibrary.org/obo/GO_0050974 GO:0050975 biolink:BiologicalProcess sensory perception of touch The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). Wikipedia:Touch go-plus.json taction|tactition|tactile sense|perception of touch http://purl.obolibrary.org/obo/GO_0050975 GO:0050978 biolink:BiologicalProcess magnetoreception by sensory perception of electrical stimulus The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish. go-plus.json magnetoreception, sensory perception of electrical stimulus|magnetoreception, using electrical stimulus|magnetoreception through electrical stimulus|magnetoreception by electrical stimulus http://purl.obolibrary.org/obo/GO_0050978 GO:0050979 biolink:BiologicalProcess magnetoreception by sensory perception of mechanical stimulus The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field. go-plus.json magnetoreception, sensory perception of mechanical stimulus|magnetoreception, using mechanical stimulus|magnetoreception through mechanical stimulus http://purl.obolibrary.org/obo/GO_0050979 UBERON:0000390 biolink:AnatomicalEntity lens nucleus The core of the crystalline lens, surrounded by the cortex. go-plus.json nucleus of lens http://purl.obolibrary.org/obo/UBERON_0000390 GO:2001185 biolink:BiologicalProcess regulation of CD8-positive, alpha-beta T cell activation Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2001185 CHEBI:86226 biolink:ChemicalSubstance lipid IIA(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86226 chebi_ph7_3 GO:2001186 biolink:BiologicalProcess negative regulation of CD8-positive, alpha-beta T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2001186 UBERON:0000391 biolink:AnatomicalEntity leptomeninx pia mater or arachnoid mater. go-plus.json leptomeninges|pia-arachnoid|arachnoid mater and pia mater|pia-arachnoid of neuraxis|arachnoidea mater et pia mater http://purl.obolibrary.org/obo/UBERON_0000391 GO:2001187 biolink:BiologicalProcess positive regulation of CD8-positive, alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_2001187 GO:2001188 biolink:BiologicalProcess regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. go-plus.json regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell http://purl.obolibrary.org/obo/GO_2001188 GO:2001189 biolink:BiologicalProcess negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. go-plus.json negative regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell http://purl.obolibrary.org/obo/GO_2001189 UBERON:0000398 biolink:AnatomicalEntity cartilage tissue of sternum Any portion of cartilage tissue that is part of the sternum go-plus.json cartilage of sternum http://purl.obolibrary.org/obo/UBERON_0000398 GO:2001180 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001180 GO:2001181 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001181 CHEBI:27904 biolink:ChemicalSubstance D-erythrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27904 chebi_ph7_3 GO:2001182 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001182 UBERON:0000395 biolink:AnatomicalEntity cochlear ganglion The group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)[MP]. distributed to the hair cells of the spiral organ. The cochlear fibers arise in bipolar cells in the spiral ganglion in the modiolus. go-plus.json vestibulocochlear VIII ganglion cochlear component|ganglion cochlearis|vestibulocochlear ganglion cochlear component|spiral ganglion of cochlea|Corti's ganglion|ganglion spirale cochleae|cochlear part of vestibulocochlear ganglion|ganglion of Corti|spiral ganglion|ganglion spirale http://purl.obolibrary.org/obo/UBERON_0000395 GO:2001183 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001183 CHEBI:27906 biolink:ChemicalSubstance ubiquinone-0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27906 chebi_ph7_3 UBERON:0000397 biolink:AnatomicalEntity colonic epithelium An epithelium that is part of a colon [Automatically generated definition]. go-plus.json large bowel epithelium|epithelium of large bowel|epithelial tissue of large bowel|large bowel epithelial tissue|epithelium of colon|epithelial tissue of colon|colon epithelial tissue|colon epithelium|posterior intestine epithelium http://purl.obolibrary.org/obo/UBERON_0000397 GO:2001184 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_2001184 CHEBI:27907 biolink:ChemicalSubstance alpha-L-rhamnopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27907 chebi_ph7_3 GO:0050983 biolink:BiologicalProcess obsolete deoxyhypusine biosynthetic process from spermidine OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+. EC:2.5.1.46|MetaCyc:2.5.1.46-RXN go-plus.json deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase|deoxyhypusine formation from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase|[eIF-5A]-deoxyhypusine synthase activity|spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase|(4-aminobutyl)lysine synthase activity|spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase|spermidine degradation to deoxyhypusine, using deoxyhypusine synthase http://purl.obolibrary.org/obo/GO_0050983 GO:0050984 biolink:BiologicalProcess peptidyl-serine sulfation The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine. RESID:AA0361 go-plus.json http://purl.obolibrary.org/obo/GO_0050984 GO:0050981 biolink:BiologicalProcess detection of electrical stimulus The series of events by which an electrical stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0050981 PO:0000289 biolink:OntologyClass sieve tube element A sieve element (PO:0025406) that is part of a sieve tube (PO:0025416) and has as parts sieve areas aggregated into sieve plates (GO:0097218). go-plus.json miembro del tubo criboso (Spanish, exact)|師(篩）管要素 (Japanese, exact)|sieve tube segment (exact)|sieve tube member (exact)|sieve-tube element (exact) http://purl.obolibrary.org/obo/PO_0000289 GO:0050982 biolink:BiologicalProcess detection of mechanical stimulus The series of events by which a mechanical stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0050982 GO:0050987 biolink:BiologicalProcess obsolete enzyme active site formation via O-sulfo-L-serine OBSOLETE. The transient sulfation of peptidyl-serine to form O-sulfo-L-serine. RESID:AA0361 go-plus.json http://purl.obolibrary.org/obo/GO_0050987 GO:0050988 biolink:BiologicalProcess N-terminal peptidyl-methionine carboxylation The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine. RESID:AA0363 go-plus.json http://purl.obolibrary.org/obo/GO_0050988 GO:0050985 biolink:BiologicalProcess peptidyl-threonine sulfation The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine. RESID:AA0362 go-plus.json http://purl.obolibrary.org/obo/GO_0050985 GO:0050986 biolink:BiologicalProcess isopeptide cross-linking via N-(L-isoglutamyl)-glycine The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25. RESID:AA0360 go-plus.json http://purl.obolibrary.org/obo/GO_0050986 GO:2001116 biolink:BiologicalProcess methanopterin-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a methanopterin. go-plus.json methanopterin biosynthesis http://purl.obolibrary.org/obo/GO_2001116 GO:2001117 biolink:BiologicalProcess tetrahydromethanopterin metabolic process The chemical reactions and pathways involving a tetrahydromethanopterin. go-plus.json tetrahydromethanopterin metabolism http://purl.obolibrary.org/obo/GO_2001117 GO:0050989 biolink:BiologicalProcess N-terminal protein amino acid carboxylation The carboxylation of the N-terminal amino acid of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0050989 GO:2001118 biolink:BiologicalProcess tetrahydromethanopterin biosynthetic process The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin. go-plus.json tetrahydromethanopterin biosynthesis http://purl.obolibrary.org/obo/GO_2001118 GO:2001119 biolink:BiologicalProcess methanofuran metabolic process The chemical reactions and pathways involving a methanofuran. go-plus.json methanofuran metabolism http://purl.obolibrary.org/obo/GO_2001119 CHEBI:62286 biolink:ChemicalSubstance 2'-deoxyinosine 5'-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62286 chebi_ph7_3 CHEBI:86258 biolink:ChemicalSubstance uridine-5'-aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_86258 chebi_ph7_3 CHEBI:62287 biolink:ChemicalSubstance alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_62287 chebi_ph7_3 GO:0060310 biolink:BiologicalProcess regulation of elastin catabolic process Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. go-plus.json regulation of elastin breakdown|regulation of elastin catabolism|regulation of elastin degradation http://purl.obolibrary.org/obo/GO_0060310 GO:2001110 biolink:BiologicalProcess negative regulation of lens epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2001110 GO:0060311 biolink:BiologicalProcess negative regulation of elastin catabolic process Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. go-plus.json negative regulation of elastin catabolism|negative regulation of elastin degradation|negative regulation of elastin breakdown|down-regulation of elastin catabolic process http://purl.obolibrary.org/obo/GO_0060311 GO:0060312 biolink:BiologicalProcess regulation of blood vessel remodeling Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0060312 GO:2001111 biolink:BiologicalProcess positive regulation of lens epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_2001111 GO:0060313 biolink:BiologicalProcess negative regulation of blood vessel remodeling Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. go-plus.json inhibition of blood vessel remodeling|down-regulation of blood vessel remodeling http://purl.obolibrary.org/obo/GO_0060313 GO:2001112 biolink:BiologicalProcess regulation of cellular response to hepatocyte growth factor stimulus Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. go-plus.json regulation of cellular response to HGF stimulus http://purl.obolibrary.org/obo/GO_2001112 GO:0098929 biolink:CellularComponent extrinsic component of spine apparatus membrane The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098929 goslim_synapse GO:2001113 biolink:BiologicalProcess negative regulation of cellular response to hepatocyte growth factor stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. go-plus.json negative regulation of cellular response to HGF stimulus http://purl.obolibrary.org/obo/GO_2001113 GO:0060314 biolink:BiologicalProcess regulation of ryanodine-sensitive calcium-release channel activity Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0060314 GO:2001114 biolink:BiologicalProcess positive regulation of cellular response to hepatocyte growth factor stimulus Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. go-plus.json positive regulation of cellular response to HGF stimulus http://purl.obolibrary.org/obo/GO_2001114 GO:0098927 biolink:BiologicalProcess vesicle-mediated transport between endosomal compartments A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0098927 GO:0060315 biolink:BiologicalProcess negative regulation of ryanodine-sensitive calcium-release channel activity Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0060315 GO:0060316 biolink:BiologicalProcess positive regulation of ryanodine-sensitive calcium-release channel activity Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0060316 GO:2001115 biolink:BiologicalProcess methanopterin-containing compound metabolic process The chemical reactions and pathways involving a methanopterin. go-plus.json methanopterin metabolism http://purl.obolibrary.org/obo/GO_2001115 GO:0098928 biolink:BiologicalProcess presynaptic signal transduction Signal transduction in which the initial step occurs in a presynapse. go-plus.json presynaptic signaling pathway http://purl.obolibrary.org/obo/GO_0098928 goslim_synapse|gocheck_do_not_manually_annotate GO:0060317 biolink:BiologicalProcess cardiac epithelial to mesenchymal transition A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json heart epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0060317 GO:0098925 biolink:BiologicalProcess retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. go-plus.json http://purl.obolibrary.org/obo/GO_0098925 goslim_synapse PO:0000290 biolink:OntologyClass tracheary element A native plant cell (PO:0025606) that has a lignified cell wall with secondary thickening and bordered pits. go-plus.json elemento de traqueida (Spanish, exact)|管状要素 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000290 GO:0098926 biolink:BiologicalProcess postsynaptic signal transduction Signal transduction in which the initial step occurs in a postsynapse. go-plus.json postsynaptic signaling pathway http://purl.obolibrary.org/obo/GO_0098926 goslim_synapse|gocheck_do_not_manually_annotate GO:0060318 biolink:BiologicalProcess definitive erythrocyte differentiation Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis. go-plus.json definitive RBC differentiation|definitive red blood cell differentiation|definitive erythropoiesis http://purl.obolibrary.org/obo/GO_0060318 GO:0098923 biolink:BiologicalProcess retrograde trans-synaptic signaling by soluble gas Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0098923 goslim_synapse GO:0060319 biolink:BiologicalProcess primitive erythrocyte differentiation Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis. go-plus.json primitive RBC differentiation|primitive red blood cell differentiation|primitive erythropoiesis http://purl.obolibrary.org/obo/GO_0060319 GO:0098924 biolink:BiologicalProcess retrograde trans-synaptic signaling by nitric oxide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. go-plus.json http://purl.obolibrary.org/obo/GO_0098924 goslim_synapse PO:0000293 biolink:OntologyClass guard cell One of a pair of cells flanking the stomatal pore. go-plus.json 孔辺細胞 (Japanese, exact)|célula guardiana (Spanish, exact)|occlusive cell (exact) http://purl.obolibrary.org/obo/PO_0000293 GO:0098921 biolink:BiologicalProcess retrograde trans-synaptic signaling by endocannabinoid Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0098921 goslim_synapse GO:0050980 biolink:BiologicalProcess detection of light stimulus involved in magnetoreception The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field. go-plus.json sensory transduction of light stimulus during magnetoreception|magnetoreception, detection of light stimulus|magnetoreception, sensory detection of light stimulus|magnetoreception, sensory transduction of light stimulus|sensory detection of light stimulus during magnetoreception http://purl.obolibrary.org/obo/GO_0050980 GO:0098922 biolink:CellularComponent extrinsic component of dense core granule membrane The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json http://purl.obolibrary.org/obo/GO_0098922 GO:0098920 biolink:BiologicalProcess retrograde trans-synaptic signaling by lipid Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0098920 goslim_synapse GO:0050994 biolink:BiologicalProcess regulation of lipid catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. go-plus.json regulation of lipid degradation|regulation of lipid breakdown|regulation of lipid catabolism http://purl.obolibrary.org/obo/GO_0050994 GO:0050995 biolink:BiologicalProcess negative regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. go-plus.json inhibition of lipid catabolic process|negative regulation of lipid catabolism|down regulation of lipid catabolic process|downregulation of lipid catabolic process|negative regulation of lipid degradation|negative regulation of lipid breakdown|down-regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050995 GO:1902508 biolink:CellularComponent 2-iminoacetate synthase complex A protein complex which is capable of 2-iminoacetate synthase activity. go-plus.json ThiH-ThiG complex http://purl.obolibrary.org/obo/GO_1902508 GO:0050992 biolink:BiologicalProcess dimethylallyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate. go-plus.json dimethylallyl pyrophosphate biosynthesis|dimethylallyl pyrophosphate biosynthetic process|dimethylallyl diphosphate biosynthesis|dimethylallyl diphosphate anabolism|dimethylallyl diphosphate synthesis|dimethylallyl diphosphate formation|DPP biosynthesis|DPP biosynthetic process http://purl.obolibrary.org/obo/GO_0050992 GO:0050993 biolink:BiologicalProcess dimethylallyl diphosphate metabolic process The chemical reactions and pathways involving dimethylallyl diphosphate. go-plus.json DPP metabolic process|DPP metabolism|dimethylallyl pyrophosphate metabolism|dimethylallyl diphosphate metabolism|dimethylallyl pyrophosphate metabolic process http://purl.obolibrary.org/obo/GO_0050993 GO:1902509 biolink:CellularComponent methionine-importing complex A protein complex which is capable of methionine-importing activity. go-plus.json methionine importer complex|methionine importing complex http://purl.obolibrary.org/obo/GO_1902509 GO:1902506 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902506 GO:0050998 biolink:MolecularActivity nitric-oxide synthase binding Binding to nitric-oxide synthase. go-plus.json NOS binding http://purl.obolibrary.org/obo/GO_0050998 GO:1902507 biolink:CellularComponent thiazole synthase complex A protein complex which is capable of thiazole synthase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902507 GO:0050999 biolink:BiologicalProcess regulation of nitric-oxide synthase activity Any process that modulates the activity of the enzyme nitric-oxide synthase. go-plus.json NOS regulator|nitric-oxide synthase regulator|regulation of NOS activity http://purl.obolibrary.org/obo/GO_0050999 GO:1902504 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902504 GO:0050996 biolink:BiologicalProcess positive regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. go-plus.json up-regulation of lipid catabolic process|upregulation of lipid catabolic process|positive regulation of lipid catabolism|positive regulation of lipid degradation|positive regulation of lipid breakdown|up regulation of lipid catabolic process|activation of lipid catabolic process|stimulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050996 GO:1902505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902505 GO:0050997 biolink:MolecularActivity quaternary ammonium group binding Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. go-plus.json quaternary amine binding http://purl.obolibrary.org/obo/GO_0050997 GO:2001127 biolink:BiologicalProcess methane biosynthetic process from formic acid The chemical reactions and pathways resulting in the formation of a methane from a formic acid. go-plus.json http://purl.obolibrary.org/obo/GO_2001127 GO:1902502 biolink:CellularComponent multivesicular body HOPS complex Any HOPS complex that is part of a multivesicular body membrane. go-plus.json multivesicular body membrane HOPS complex http://purl.obolibrary.org/obo/GO_1902502 GO:2001128 biolink:BiologicalProcess methane biosynthetic process from methylamine The chemical reactions and pathways resulting in the formation of a methane from a methylamine. go-plus.json http://purl.obolibrary.org/obo/GO_2001128 GO:1902503 biolink:CellularComponent adenylyltransferase complex A protein complex which is capable of adenylyltransferase activity. go-plus.json ThiF-ThiS complex http://purl.obolibrary.org/obo/GO_1902503 GO:2001129 biolink:BiologicalProcess methane biosynthetic process from dimethylamine The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_2001129 GO:1902500 biolink:CellularComponent vacuolar HOPS complex Any HOPS complex that is part of a vacuolar membrane. go-plus.json vacuolar membrane HOPS complex http://purl.obolibrary.org/obo/GO_1902500 GO:1902501 biolink:CellularComponent lysosomal HOPS complex Any HOPS complex that is part of a lysosomal membrane. go-plus.json lysosomal membrane HOPS complex http://purl.obolibrary.org/obo/GO_1902501 GO:2001120 biolink:BiologicalProcess methanofuran biosynthetic process The chemical reactions and pathways resulting in the formation of a methanofuran. go-plus.json methanofuran biosynthesis http://purl.obolibrary.org/obo/GO_2001120 GO:2001121 biolink:BiologicalProcess coenzyme gamma-F420-2 biosynthetic process The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2. go-plus.json coenzyme gamma-F420-2 biosynthesis http://purl.obolibrary.org/obo/GO_2001121 GO:0060300 biolink:BiologicalProcess regulation of cytokine activity Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060300 GO:2001122 biolink:BiologicalProcess maltoheptaose metabolic process The chemical reactions and pathways involving a maltoheptaose. go-plus.json maltoheptaose metabolism http://purl.obolibrary.org/obo/GO_2001122 GO:0060301 biolink:BiologicalProcess positive regulation of cytokine activity Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060301 GO:2001123 biolink:BiologicalProcess maltoheptaose catabolic process The chemical reactions and pathways resulting in the breakdown of a maltoheptaose. go-plus.json maltoheptaose catabolism http://purl.obolibrary.org/obo/GO_2001123 GO:0060302 biolink:BiologicalProcess negative regulation of cytokine activity Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. go-plus.json http://purl.obolibrary.org/obo/GO_0060302 GO:2001124 biolink:BiologicalProcess regulation of translational frameshifting Any process that modulates the frequency, rate or extent of translational frameshifting. go-plus.json http://purl.obolibrary.org/obo/GO_2001124 GO:0060303 biolink:BiologicalProcess regulation of nucleosome density Any process that modulates the number of nucleosomes in a given region of a chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0060303 GO:2001125 biolink:BiologicalProcess negative regulation of translational frameshifting Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting. go-plus.json http://purl.obolibrary.org/obo/GO_2001125 GO:0098938 biolink:CellularComponent actin cytoskeleton of dendritic spine The actin cytoskeleton that is part of a dendritic spine. go-plus.json http://purl.obolibrary.org/obo/GO_0098938 goslim_synapse GO:0060304 biolink:BiologicalProcess regulation of phosphatidylinositol dephosphorylation Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol. go-plus.json regulation of phosphoinositide dephosphorylation http://purl.obolibrary.org/obo/GO_0060304 GO:0098939 biolink:BiologicalProcess dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in nerve cell dendrites. go-plus.json http://purl.obolibrary.org/obo/GO_0098939 goslim_synapse GO:2001126 biolink:BiologicalProcess positive regulation of translational frameshifting Any process that activates or increases the frequency, rate or extent of translational frameshifting. go-plus.json http://purl.obolibrary.org/obo/GO_2001126 GO:0060305 biolink:BiologicalProcess regulation of cell diameter Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell. go-plus.json regulation of cell width http://purl.obolibrary.org/obo/GO_0060305 GO:0098936 biolink:CellularComponent intrinsic component of postsynaptic membrane The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0098936 goslim_synapse GO:0060306 biolink:BiologicalProcess regulation of membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative. go-plus.json http://purl.obolibrary.org/obo/GO_0060306 GO:0060307 biolink:BiologicalProcess regulation of ventricular cardiac muscle cell membrane repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte. go-plus.json regulation of ventricular cardiac muscle cell repolarization|regulation of ventricular cardiomyocyte membrane repolarization|ventricular repolarization|regulation of ventricular cardiac muscle repolarization|electrocardiogram T wave http://purl.obolibrary.org/obo/GO_0060307 GO:0098937 biolink:BiologicalProcess anterograde dendritic transport The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites. go-plus.json http://purl.obolibrary.org/obo/GO_0098937 goslim_synapse GO:0060308 biolink:MolecularActivity GTP cyclohydrolase I regulator activity Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0060308 GO:0098934 biolink:BiologicalProcess retrograde dendritic transport The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body. go-plus.json http://purl.obolibrary.org/obo/GO_0098934 goslim_synapse GO:0060309 biolink:BiologicalProcess elastin catabolic process The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue. go-plus.json elastin catabolism|elastin degradation|elastin breakdown http://purl.obolibrary.org/obo/GO_0060309 GO:0098935 biolink:BiologicalProcess dendritic transport The directed movement of organelles or molecules along microtubules in dendrites. go-plus.json dendrite cargo transport http://purl.obolibrary.org/obo/GO_0098935 goslim_synapse PO:0000282 biolink:OntologyClass trichome A unicellular or multicellular plant structure (PO:0009011) that forms a non-sclerified outgrowth from the epidermis (PO:0005679). go-plus.json non-secretory trichome (narrow)|capilli (narrow)|bristle (broad)|capillus (narrow)|glochidium (narrow)|cilium (narrow)|squama (narrow)|cilia (narrow)|squamella (narrow)|barb trichome (broad)|lepides (narrow)|lepis (narrow)|glochidia (narrow)|hair (narrow)|setae (related)|squamellae (narrow)|squamae (narrow)|毛茸、糸状体、毛 (Japanese, exact)|scale (narrow)|glochid (narrow)|squamule (narrow)|seta (related)|tricoma (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000282 GO:0098932 biolink:BiologicalProcess disruption by virus of host cell wall peptidoglycan during virus entry A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry. VZ:3940 go-plus.json degradation of host peptidoglycans during virus entry|degradation of host cell wall peptidoglycan by virus|catabolism of host cell wall peptidoglycan by virus|disassembly by virus of host cell wall peptidoglycan http://purl.obolibrary.org/obo/GO_0098932 GO:0050990 biolink:BiologicalProcess N-terminal protein amino acid carbamoylation The carbamoylation of the N-terminal amino acid of proteins. go-plus.json N-terminal protein amino acid carbamylation http://purl.obolibrary.org/obo/GO_0050990 GO:0050991 biolink:BiologicalProcess obsolete enzyme active site formation via O-sulfo-L-threonine OBSOLETE. The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine. RESID:AA0362 go-plus.json http://purl.obolibrary.org/obo/GO_0050991 GO:0098933 biolink:BiologicalProcess disruption by symbiont of host cell envelope The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0098933 GO:0098930 biolink:BiologicalProcess axonal transport The directed movement of organelles or molecules along microtubules in axons. Wikipedia:Axoplasmic_transport go-plus.json axon cargo transport|axoplasmic transport http://purl.obolibrary.org/obo/GO_0098930 goslim_synapse GO:0098931 biolink:BiologicalProcess virion attachment to host cell flagellum The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface. VZ:3949 go-plus.json http://purl.obolibrary.org/obo/GO_0098931 GO:1902519 biolink:BiologicalProcess response to docetaxel trihydrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus. go-plus.json response to docetaxel http://purl.obolibrary.org/obo/GO_1902519 gocheck_do_not_manually_annotate GO:1902517 biolink:CellularComponent glycerol-3-phosphate-transporting ATPase complex A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902517 GO:1902518 biolink:BiologicalProcess response to cyclophosphamide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902518 gocheck_do_not_manually_annotate GO:1902515 biolink:CellularComponent thioredoxin-disulfide reductase complex A protein complex which is capable of thioredoxin-disulfide reductase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902515 GO:1902516 biolink:MolecularActivity sn-glycerol 3-phosphate binding Binding to sn-glycerol 3-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1902516 GO:2001138 biolink:BiologicalProcess regulation of phospholipid transport Any process that modulates the frequency, rate or extent of phospholipid transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001138 CHEBI:86273 biolink:ChemicalSubstance 4-hydroxylysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86273 GO:1902513 biolink:BiologicalProcess regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of organelle transport along microtubule. go-plus.json regulation of microtubule-based organelle localization http://purl.obolibrary.org/obo/GO_1902513 GO:2001139 biolink:BiologicalProcess negative regulation of phospholipid transport Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001139 GO:1902514 biolink:BiologicalProcess regulation of calcium ion transmembrane transport via high voltage-gated calcium channel Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel. go-plus.json regulation of generation of L-type calcium current http://purl.obolibrary.org/obo/GO_1902514 CHEBI:86274 biolink:ChemicalSubstance N-[(R)-2-hydroxyacyl]phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86274 chebi_ph7_3 GO:1902511 biolink:BiologicalProcess negative regulation of apoptotic DNA fragmentation Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation. go-plus.json down regulation of endonucleolytic DNA catabolic process involved in apoptosis|downregulation of DNA catabolism during apoptosis|downregulation of endonucleolytic DNA catabolic process involved in apoptosis|downregulation of DNA fragmentation involved in apoptotic nuclear change|down-regulation of apoptotic DNA fragmentation|down regulation of DNA fragmentation involved in apoptotic nuclear change|down-regulation of DNA catabolic process during apoptosis|down-regulation of DNA catabolism during apoptosis|negative regulation of DNA catabolic process during apoptosis|negative regulation of DNA catabolism during apoptosis|inhibition of DNA fragmentation involved in apoptotic nuclear change|inhibition of apoptotic DNA fragmentation|negative regulation of endonucleolytic DNA catabolic process involved in apoptosis|down-regulation of endonucleolytic DNA catabolic process involved in apoptosis|inhibition of DNA catabolism during apoptosis|downregulation of DNA catabolic process during apoptosis|inhibition of endonucleolytic DNA catabolic process involved in apoptosis|down regulation of DNA catabolic process during apoptosis|inhibition of DNA catabolic process during apoptosis|down regulation of apoptotic DNA fragmentation|down-regulation of DNA fragmentation involved in apoptotic nuclear change|negative regulation of DNA fragmentation involved in apoptotic nuclear change|down regulation of DNA catabolism during apoptosis|downregulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1902511 CHEBI:86275 biolink:ChemicalSubstance N-(1,2-saturated acyl)phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86275 chebi_ph7_3 GO:1902512 biolink:BiologicalProcess positive regulation of apoptotic DNA fragmentation Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation. go-plus.json upregulation of endonucleolytic DNA catabolic process involved in apoptosis|positive regulation of DNA fragmentation involved in apoptotic nuclear change|up regulation of apoptotic DNA fragmentation|activation of apoptotic DNA fragmentation|up regulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of DNA catabolic process during apoptosis|up regulation of DNA catabolism during apoptosis|activation of DNA catabolic process during apoptosis|activation of DNA catabolism during apoptosis|positive regulation of DNA catabolism during apoptosis|up regulation of endonucleolytic DNA catabolic process involved in apoptosis|positive regulation of endonucleolytic DNA catabolic process involved in apoptosis|activation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of apoptotic DNA fragmentation|positive regulation of DNA catabolic process during apoptosis|up regulation of DNA catabolic process during apoptosis|up-regulation of DNA catabolism during apoptosis|up-regulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of apoptotic DNA fragmentation|activation of DNA fragmentation involved in apoptotic nuclear change|upregulation of DNA catabolism during apoptosis|upregulation of DNA catabolic process during apoptosis http://purl.obolibrary.org/obo/GO_1902512 GO:1902510 biolink:BiologicalProcess regulation of apoptotic DNA fragmentation Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation. go-plus.json regulation of DNA catabolism during apoptosis|regulation of chromatinolysis|regulation of endonucleolytic DNA catabolic process involved in apoptosis|regulation of DNA fragmentation involved in apoptotic nuclear change|regulation of DNA fragmentation|regulation of DNA catabolic process during apoptosis http://purl.obolibrary.org/obo/GO_1902510 PR:000009054 biolink:Protein insulin An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof. go-plus.json INS http://purl.obolibrary.org/obo/PR_000009054 GO:0060330 biolink:BiologicalProcess regulation of response to interferon-gamma Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. go-plus.json regulation of response to type II IFN|regulation of response to gamma-interferon|regulation of response to type II interferon|regulation of response to immune interferon http://purl.obolibrary.org/obo/GO_0060330 GO:2001130 biolink:BiologicalProcess methane biosynthetic process from trimethylamine The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_2001130 GO:0060331 biolink:BiologicalProcess negative regulation of response to interferon-gamma Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. go-plus.json negative regulation of response to immune interferon|negative regulation of response to type II interferon|negative regulation of response to type II IFN|negative regulation of response to gamma-interferon http://purl.obolibrary.org/obo/GO_0060331 GO:0060332 biolink:BiologicalProcess positive regulation of response to interferon-gamma Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. go-plus.json positive regulation of response to immune interferon|positive regulation of response to type II IFN|positive regulation of response to type II interferon|positive regulation of response to gamma-interferon http://purl.obolibrary.org/obo/GO_0060332 GO:2001131 biolink:BiologicalProcess methane biosynthetic process from dimethyl sulfide The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide. go-plus.json http://purl.obolibrary.org/obo/GO_2001131 GO:0098909 biolink:BiologicalProcess regulation of cardiac muscle cell action potential involved in regulation of contraction Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0098909 GO:0060333 biolink:BiologicalProcess interferon-gamma-mediated signaling pathway A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far. go-plus.json immune interferon signaling pathway|type II IFN-mediated signaling pathway|type II interferon-mediated signaling pathway|interferon-gamma-mediated signalling pathway|gamma-interferon-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060333 GO:2001132 biolink:BiologicalProcess methane biosynthetic process from 3-(methylthio)propionic acid The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid. go-plus.json http://purl.obolibrary.org/obo/GO_2001132 GO:2001133 biolink:BiologicalProcess methane biosynthetic process from methanethiol The chemical reactions and pathways resulting in the formation of a methane from a methanethiol. go-plus.json http://purl.obolibrary.org/obo/GO_2001133 GO:0060334 biolink:BiologicalProcess regulation of interferon-gamma-mediated signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor. go-plus.json regulation of interferon-gamma-mediated signalling pathway|regulation of type II interferon-mediated signaling pathway|regulation of type II IFN-mediated signaling pathway|regulation of gamma-interferon-mediated signaling pathway|regulation of immune interferon signaling pathway http://purl.obolibrary.org/obo/GO_0060334 GO:0098907 biolink:BiologicalProcess regulation of SA node cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json regulation of SAN cardiac muscle cell action potential|regulation of sinus node cardiac muscle cell action potential|regulation of SA node cardiac muscle cell action potential|regulation of sinoatrial node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098907 GO:0060335 biolink:BiologicalProcess positive regulation of interferon-gamma-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor. go-plus.json positive regulation of type II IFN-mediated pathway|positive regulation of interferon-gamma-mediated signalling pathway|positive regulation of type II interferon-mediated signaling pathway|positive regulation of immune interferon-mediated signaling pathway|positive regulation of gamma-interferon-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060335 GO:2001134 biolink:BiologicalProcess methane biosynthetic process from carbon monoxide The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide. go-plus.json http://purl.obolibrary.org/obo/GO_2001134 GO:0098908 biolink:BiologicalProcess regulation of neuronal action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json generation of action potential http://purl.obolibrary.org/obo/GO_0098908 GO:0060336 biolink:BiologicalProcess negative regulation of interferon-gamma-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor. go-plus.json negative regulation of interferon-gamma-mediated signalling pathway|negative regulation of gamma-interferon-mediated signaling pathway|negative regulation of type II IFN-mediated signaling pathway|negative regulation of immune interferon-mediated signaling pathway|negative regulation of type II interferon-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060336 GO:2001135 biolink:BiologicalProcess regulation of endocytic recycling Any process that modulates the frequency, rate or extent of endocytic recycling. go-plus.json regulation of retrograde transport of endocytic vesicles http://purl.obolibrary.org/obo/GO_2001135 GO:2001136 biolink:BiologicalProcess negative regulation of endocytic recycling Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling. go-plus.json negative regulation of retrograde transport of endocytic vesicles http://purl.obolibrary.org/obo/GO_2001136 GO:0060337 biolink:BiologicalProcess type I interferon signaling pathway A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json type I interferon-activated signaling pathway|type I interferon-mediated signaling pathway|type I interferon-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0060337 GO:0098905 biolink:BiologicalProcess regulation of bundle of His cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json regulation of bundle of His cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098905 GO:2001137 biolink:BiologicalProcess positive regulation of endocytic recycling Any process that activates or increases the frequency, rate or extent of endocytic recycling. go-plus.json positive regulation of retrograde transport of endocytic vesicles http://purl.obolibrary.org/obo/GO_2001137 GO:0098906 biolink:BiologicalProcess regulation of Purkinje myocyte action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json http://purl.obolibrary.org/obo/GO_0098906 GO:0060338 biolink:BiologicalProcess regulation of type I interferon-mediated signaling pathway Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. go-plus.json regulation of type I interferon-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0060338 GO:0060339 biolink:BiologicalProcess negative regulation of type I interferon-mediated signaling pathway Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. go-plus.json negative regulation of type I interferon-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0060339 GO:0098903 biolink:BiologicalProcess regulation of membrane repolarization during action potential Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0098903 GO:0098904 biolink:BiologicalProcess regulation of AV node cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json regulation of atrioventricular node cardiac muscle cell action potential|regulation of AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098904 GO:0098901 biolink:BiologicalProcess regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json http://purl.obolibrary.org/obo/GO_0098901 GO:0098902 biolink:BiologicalProcess regulation of membrane depolarization during action potential Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0098902 PO:0000272 biolink:OntologyClass protoxylem A portion of primary xylem (PO:0000272) tissue that has as part one or more protoxylem tracheary elements (PO:0025575) embedded in parenchyma (PO:0005421) tissue. go-plus.json protoxilema (Spanish, exact)|原生木（質）部 (Japanese, exact)|portion of protoxylem tissue (exact) http://purl.obolibrary.org/obo/PO_0000272 GO:0098900 biolink:BiologicalProcess regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json http://purl.obolibrary.org/obo/GO_0098900 PO:0000256 biolink:OntologyClass root hair cell A root epidermal cell (PO:0025164) that develops from a trichoblast (PO:0000262) and has as part a root hair (GO:0035618). go-plus.json célula del pelo de la raíz (Spanish, exact)|根毛細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000256 GO:1902528 biolink:BiologicalProcess regulation of protein linear polyubiquitination Any process that modulates the frequency, rate or extent of protein linear polyubiquitination. go-plus.json regulation of M1 linkage http://purl.obolibrary.org/obo/GO_1902528 GO:1902529 biolink:BiologicalProcess negative regulation of protein linear polyubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination. go-plus.json downregulation of protein linear polyubiquitination|inhibition of M1 linkage|down-regulation of protein linear polyubiquitination|down-regulation of M1 linkage|negative regulation of M1 linkage|inhibition of protein linear polyubiquitination|downregulation of M1 linkage|down regulation of M1 linkage|down regulation of protein linear polyubiquitination http://purl.obolibrary.org/obo/GO_1902529 GO:1902526 biolink:BiologicalProcess negative regulation of protein monoubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination. go-plus.json downregulation of protein monoubiquitination|down regulation of protein monoubiquitination|down-regulation of protein monoubiquitylation|negative regulation of protein monoubiquitylation|inhibition of protein monoubiquitination|down-regulation of protein monoubiquitinylation|negative regulation of protein monoubiquitinylation|downregulation of protein monoubiquitylation|down regulation of protein monoubiquitylation|downregulation of protein monoubiquitinylation|inhibition of protein monoubiquitylation|down regulation of protein monoubiquitinylation|down-regulation of protein monoubiquitination|inhibition of protein monoubiquitinylation http://purl.obolibrary.org/obo/GO_1902526 CHEBI:86261 biolink:ChemicalSubstance (3S)-beta-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86261 GO:1902527 biolink:BiologicalProcess positive regulation of protein monoubiquitination Any process that activates or increases the frequency, rate or extent of protein monoubiquitination. go-plus.json up-regulation of protein monoubiquitinylation|activation of protein monoubiquitinylation|upregulation of protein monoubiquitination|positive regulation of protein monoubiquitylation|up regulation of protein monoubiquitylation|positive regulation of protein monoubiquitinylation|up regulation of protein monoubiquitinylation|up-regulation of protein monoubiquitination|activation of protein monoubiquitination|upregulation of protein monoubiquitylation|upregulation of protein monoubiquitinylation|up regulation of protein monoubiquitination|up-regulation of protein monoubiquitylation|activation of protein monoubiquitylation http://purl.obolibrary.org/obo/GO_1902527 GO:2001149 biolink:BiologicalProcess negative regulation of dipeptide transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport. go-plus.json negative regulation of dipeptide membrane transport http://purl.obolibrary.org/obo/GO_2001149 GO:1902524 biolink:BiologicalProcess positive regulation of protein K48-linked ubiquitination Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination. go-plus.json up regulation of protein K48-linked ubiquitination|up-regulation of protein K48-linked polyubiquitination|activation of protein K48-linked ubiquitination|upregulation of protein K48-linked polyubiquitination|up-regulation of protein K48-linked ubiquitination|up regulation of protein K48-linked polyubiquitination|upregulation of protein K48-linked ubiquitination|positive regulation of protein K48-linked polyubiquitination|activation of protein K48-linked polyubiquitination http://purl.obolibrary.org/obo/GO_1902524 CHEBI:86262 biolink:ChemicalSubstance D-kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86262 GO:1902525 biolink:BiologicalProcess regulation of protein monoubiquitination Any process that modulates the frequency, rate or extent of protein monoubiquitination. go-plus.json regulation of protein monoubiquitylation|regulation of protein monoubiquitinylation http://purl.obolibrary.org/obo/GO_1902525 GO:1902522 biolink:BiologicalProcess response to 4'-epidoxorubicin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus. go-plus.json response to epirubicin http://purl.obolibrary.org/obo/GO_1902522 gocheck_do_not_manually_annotate CHEBI:86264 biolink:ChemicalSubstance rat metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_86264 GO:1902523 biolink:BiologicalProcess positive regulation of protein K63-linked ubiquitination Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination. go-plus.json up regulation of protein K63-linked ubiquitination|up-regulation of protein K63-linked polyubiquitination|activation of protein K63-linked ubiquitination|upregulation of protein K63-linked polyubiquitination|up-regulation of protein K63-linked ubiquitination|up regulation of protein K63-linked polyubiquitination|positive regulation of protein K63-linked polyubiquitination|activation of protein K63-linked polyubiquitination|upregulation of protein K63-linked ubiquitination http://purl.obolibrary.org/obo/GO_1902523 CHEBI:86265 biolink:ChemicalSubstance N-(1,2-saturated acyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86265 chebi_ph7_3 GO:1902520 biolink:BiologicalProcess response to doxorubicin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902520 gocheck_do_not_manually_annotate PR:000009064 biolink:Protein insulin receptor A protein that is a translation product of the human INSR gene or a 1:1 ortholog thereof. go-plus.json CD220|IR|INSR http://purl.obolibrary.org/obo/PR_000009064 CHEBI:86266 biolink:ChemicalSubstance N-[(2R)-hydroxyacyl]sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86266 chebi_ph7_3 GO:1902521 biolink:BiologicalProcess response to etoposide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902521 gocheck_do_not_manually_annotate GO:0060320 biolink:BiologicalProcess rejection of self pollen The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma. go-plus.json http://purl.obolibrary.org/obo/GO_0060320 GO:2001141 biolink:BiologicalProcess regulation of RNA biosynthetic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process. go-plus.json regulation of RNA anabolism|regulation of RNA synthesis|regulation of RNA formation|regulation of RNA biosynthesis http://purl.obolibrary.org/obo/GO_2001141 GO:0035397 biolink:BiologicalProcess helper T cell enhancement of adaptive immune response Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell. go-plus.json provision of T cell help http://purl.obolibrary.org/obo/GO_0035397 GO:0035398 biolink:BiologicalProcess helper T cell enhancement of T cell mediated immune response Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell. go-plus.json provision of T cell help to T cell|helper T cell enhancement of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0035398 GO:0060321 biolink:BiologicalProcess acceptance of pollen The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma. go-plus.json acceptance of non-self pollen|acceptance of self pollen http://purl.obolibrary.org/obo/GO_0060321 GO:2001142 biolink:BiologicalProcess nicotinate transport The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001142 GO:0035399 biolink:BiologicalProcess helper T cell enhancement of B cell mediated immune response Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell. go-plus.json provision of T cell help to B cell|helper T cell enhancement of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0035399 GO:2001143 biolink:BiologicalProcess N-methylnicotinate transport The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_2001143 GO:0060322 biolink:BiologicalProcess head development The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0060322 GO:2001144 biolink:BiologicalProcess regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_2001144 GO:0060323 biolink:BiologicalProcess head morphogenesis The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0060323 GO:0098918 biolink:MolecularActivity structural constituent of synapse The action of a molecule that contributes to the structural integrity of a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0098918 goslim_synapse GO:2001145 biolink:BiologicalProcess negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_2001145 GO:0060324 biolink:BiologicalProcess face development The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. go-plus.json http://purl.obolibrary.org/obo/GO_0060324 GO:2001146 biolink:BiologicalProcess positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_2001146 GO:0098919 biolink:MolecularActivity structural constituent of postsynaptic density The action of a molecule that contributes to the structural integrity of a postsynaptic density. go-plus.json http://purl.obolibrary.org/obo/GO_0098919 goslim_synapse GO:0060325 biolink:BiologicalProcess face morphogenesis The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. go-plus.json http://purl.obolibrary.org/obo/GO_0060325 GO:0098916 biolink:BiologicalProcess anterograde trans-synaptic signaling Cell-cell signaling from pre to post-synapse, across the synaptic cleft. go-plus.json http://purl.obolibrary.org/obo/GO_0098916 GO:0060326 biolink:BiologicalProcess cell chemotaxis The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). go-plus.json http://purl.obolibrary.org/obo/GO_0060326 GO:2001147 biolink:MolecularActivity camalexin binding Binding to camalexin. go-plus.json 3-(1,3-thiazol-2-yl)-1H-indole binding http://purl.obolibrary.org/obo/GO_2001147 GO:2001148 biolink:BiologicalProcess regulation of dipeptide transmembrane transport Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport. go-plus.json regulation of dipeptide membrane transport http://purl.obolibrary.org/obo/GO_2001148 GO:0060327 biolink:BiologicalProcess cytoplasmic actin-based contraction involved in cell motility The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another. go-plus.json http://purl.obolibrary.org/obo/GO_0060327 GO:0098917 biolink:BiologicalProcess retrograde trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft. go-plus.json http://purl.obolibrary.org/obo/GO_0098917 GO:0060328 biolink:BiologicalProcess cytoplasmic actin-based contraction involved in forward cell motility The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell. go-plus.json cytoplasmic actin-based contraction involved in forward cell locomotion http://purl.obolibrary.org/obo/GO_0060328 GO:0098914 biolink:BiologicalProcess membrane repolarization during atrial cardiac muscle cell action potential The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json atrial repolarization|electrocardiogram QRS complex http://purl.obolibrary.org/obo/GO_0098914 GO:0035390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0035390 GO:0060329 biolink:BiologicalProcess cytoplasmic actin-based contraction involved in rearward cell motility The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell. go-plus.json cytoplasmic actin-based contraction involved in rearward cell locomotion http://purl.obolibrary.org/obo/GO_0060329 GO:0098915 biolink:BiologicalProcess membrane repolarization during ventricular cardiac muscle cell action potential The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json ventricular repolarization|regulation of ventricular cardiac muscle repolarization|electrocardiogram T wave http://purl.obolibrary.org/obo/GO_0098915 GO:0035391 biolink:BiologicalProcess obsolete maintenance of chromatin silencing at silent mating-type cassette OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci. go-plus.json http://purl.obolibrary.org/obo/GO_0035391 GO:0098912 biolink:BiologicalProcess membrane depolarization during atrial cardiac muscle cell action potential The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json atrial cardiac muscle cell depolarization|electrocardiogram PR interval|atrial depolarization http://purl.obolibrary.org/obo/GO_0098912 GO:0098913 biolink:BiologicalProcess membrane depolarization during ventricular cardiac muscle cell action potential The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json electrocardiogram QRS complex|ventricular depolarization http://purl.obolibrary.org/obo/GO_0098913 GO:0035392 biolink:BiologicalProcess obsolete maintenance of chromatin silencing at telomere OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere. go-plus.json http://purl.obolibrary.org/obo/GO_0035392 GO:0035393 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 9 production The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CXCL9 production|Monokine induced by gamma interferon production|MIG production http://purl.obolibrary.org/obo/GO_0035393 gocheck_do_not_annotate GO:0098910 biolink:BiologicalProcess regulation of atrial cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json http://purl.obolibrary.org/obo/GO_0098910 GO:0035394 biolink:BiologicalProcess regulation of chemokine (C-X-C motif) ligand 9 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. go-plus.json regulation of MIG production|regulation of CXCL9 production http://purl.obolibrary.org/obo/GO_0035394 GO:0098911 biolink:BiologicalProcess regulation of ventricular cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. go-plus.json http://purl.obolibrary.org/obo/GO_0098911 GO:0035395 biolink:BiologicalProcess negative regulation of chemokine (C-X-C motif) ligand 9 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. go-plus.json negative regulation of CXCL9 production|negative regulation of MIG production http://purl.obolibrary.org/obo/GO_0035395 PO:0000262 biolink:OntologyClass trichoblast A root epidermal cell that is the smaller cell produced by the asymmetric division of an epidermal intial and gives rise to a root hair. go-plus.json tricoblasto (Spanish, exact)|根毛形成細胞、トリコブラスト (Japanese, exact)|hair cell (related) http://purl.obolibrary.org/obo/PO_0000262 GO:0035396 biolink:BiologicalProcess positive regulation of chemokine (C-X-C motif) ligand 9 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. go-plus.json positive regulation of MIG production|positive regulation of CXCL9 production http://purl.obolibrary.org/obo/GO_0035396 PO:0000263 biolink:OntologyClass non-hair root epidermal cell A root epidermal cell (PO:0025164) that develops from an epidermal initial (PO:0000349) and does not have as part a root hair (GO:0035618). go-plus.json atricoblasto (Spanish, exact)|非毛根形成細胞、アトリコブラスト (Japanese, exact)|atrichoblast (exact)|non-hair cell (broad) http://purl.obolibrary.org/obo/PO_0000263 GO:2001140 biolink:BiologicalProcess positive regulation of phospholipid transport Any process that activates or increases the frequency, rate or extent of phospholipid transport. go-plus.json http://purl.obolibrary.org/obo/GO_2001140 CL:0000927 biolink:Cell CD4-positive type I NK T cell secreting interleukin-4 A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses. go-plus.json CD4-positive type I NK T cell secreting IL-4|CD4-positive type I NK T-cell secreting interleukin-4|CD4-positive type I NK T-lymphocyte secreting interleukin-4|CD4-positive type I NK T lymphocyte secreting interleukin-4|CD4-positive type I NKT cell secreting interleukin-4 http://purl.obolibrary.org/obo/CL_0000927 CL:0000928 biolink:Cell activated CD4-negative, CD8-negative type I NK T cell A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers. go-plus.json activated CD4-negative, CD8-negative type I NK T-lymphocyte|activated CD4-negative, CD8-negative type I NK T lymphocyte|activated CD4-negative, CD8-negative type I NKT cell|activated CD4-negative, CD8-negative type I NK T-cell http://purl.obolibrary.org/obo/CL_0000928 CL:0000929 biolink:Cell CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses. go-plus.json CD4-negative, CD8-negative type I NK T lymphocyte secreting interferon-gamma|CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon-gamma|CD4-negative, CD8-negative type I NK T-cell secreting interferon-gamma|CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma|CD4-negative, CD8-negative type I NK T cell secreting IFN-gamma http://purl.obolibrary.org/obo/CL_0000929 CL:0000921 biolink:Cell type I NK T cell An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. go-plus.json type I NK T-lymphocyte|type I NK T lymphocyte|classical NK T cell|invariant NK T cell|type I NKT cell|type I NK T-cell http://purl.obolibrary.org/obo/CL_0000921 CL:0000922 biolink:Cell type II NK T cell An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. go-plus.json type II NK T lymphocyte|type II NKT cell|type II NK T-cell|type II NK T-lymphocyte http://purl.obolibrary.org/obo/CL_0000922 CL:0000923 biolink:Cell CD4-positive type I NK T cell A type I NK T cell that has the phenotype CD4-positive. go-plus.json CD4-positive type I NK T lymphocyte|CD4-positive type I NKT cell|CD4-positive type I NK T-cell|CD4-positive type I NK T-lymphocyte|NKT.4+.SP http://purl.obolibrary.org/obo/CL_0000923 CL:0000924 biolink:Cell CD4-negative, CD8-negative type I NK T cell A type I NK T cell that has the phenotype CD4-negative and CD8-negative. go-plus.json CD4-negative, CD8-negative type I NKT cell|CD4-negative, CD8-negative type I NK T-cell|CD4-negative, CD8-negative type I NK T-lymphocyte|CD4-negative, CD8-negative type I NK T lymphocyte|NKT.4-.Sp http://purl.obolibrary.org/obo/CL_0000924 CL:0000925 biolink:Cell activated CD4-positive type I NK T cell A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers. go-plus.json activated CD4-positive type I NK T-cell|activated CD4-positive type I NK T-lymphocyte|activated CD4-positive type I NK T lymphocyte|activated CD4-positive type I NKT cell http://purl.obolibrary.org/obo/CL_0000925 CL:0000926 biolink:Cell CD4-positive type I NK T cell secreting interferon-gamma A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses. go-plus.json CD4-positive type I NK T cell secreting IFN-gamma|CD4-positive type I NK T-lymphocyte secreting interferon-gamma|CD4-positive type I NK T-cell secreting interferon-gamma|CD4-positive type I NKT cell secreting interferon-gamma|CD4-positive type I NK T lymphocyte secreting interferon-gamma http://purl.obolibrary.org/obo/CL_0000926 GO:0015098 biolink:MolecularActivity molybdate ion transmembrane transporter activity Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid. go-plus.json molybdate transporter activity http://purl.obolibrary.org/obo/GO_0015098 GO:0015099 biolink:MolecularActivity nickel cation transmembrane transporter activity Enables the transfer of nickel (Ni) cations from one side of a membrane to the other. RHEA:29831 go-plus.json zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity http://purl.obolibrary.org/obo/GO_0015099 CHEBI:6650 biolink:ChemicalSubstance malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_6650 GO:0015094 biolink:MolecularActivity lead ion transmembrane transporter activity Enables the transfer of lead (Pb) ions from one side of a membrane to the other. go-plus.json zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity http://purl.obolibrary.org/obo/GO_0015094 GO:0015095 biolink:MolecularActivity magnesium ion transmembrane transporter activity Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other. Reactome:R-HSA-5336466|Reactome:R-HSA-5339528|Reactome:R-HSA-442661|Reactome:R-HSA-5336453|RHEA:29827|Reactome:R-HSA-5339538|Reactome:R-HSA-5336454 go-plus.json http://purl.obolibrary.org/obo/GO_0015095 GO:0015096 biolink:MolecularActivity obsolete manganese resistance permease activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json manganese resistance permease activity http://purl.obolibrary.org/obo/GO_0015096 GO:0015097 biolink:MolecularActivity mercury ion transmembrane transporter activity Enables the transfer of mercury (Hg) ions from one side of a membrane to the other. RHEA:32815 go-plus.json http://purl.obolibrary.org/obo/GO_0015097 CL:0000930 biolink:Cell CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses. go-plus.json CD4-negative, CD8-negative type I NK T lymphocyte secreting interleukin-4|CD4-negative, CD8-negative type I NKT cell secreting interleukin-4|CD4-negative, CD8-negative type I NK T-cell secreting interleukin-4|CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleukin-4|CD4-negative, CD8-negative type I NK T cell secreting IL-4 http://purl.obolibrary.org/obo/CL_0000930 CL:0000931 biolink:Cell activated type II NK T cell A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. go-plus.json activated type II NK T lymphocyte|activated type II NK T-cell|activated type II NKT cell|activated type II NK T-lymphocyte http://purl.obolibrary.org/obo/CL_0000931 CL:0000932 biolink:Cell type II NK T cell secreting interferon-gamma A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers. go-plus.json type II NK T lymphocyte secreting interferon-gamma|type II NK T-lymphocyte secreting interferon-gamma|type II NK T-cell secreting interferon-gamma|type II NKT cell secreting interferon-gamma|type II NK T cell secreting IFN-gamma http://purl.obolibrary.org/obo/CL_0000932 CL:0000933 biolink:Cell type II NK T cell secreting interleukin-4 A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. go-plus.json type II NK T-lymphocyte secreting interleukin-4|type II NK T cell secreting IL-4|type II NK T lymphocyte secreting interleukin-4|type II NKT cell secreting interleukin-4|type II NK T-cell secreting interleukin-4 http://purl.obolibrary.org/obo/CL_0000933 CL:0000934 biolink:Cell CD4-positive, alpha-beta cytotoxic T cell A CD4-positive, alpha-beta T cell that has cytotoxic function. go-plus.json CD4-positive, alpha-beta cytotoxic T-lymphocyte|CD4-positive, alpha-beta cytotoxic T lymphocyte|CD4-positive, alpha-beta cytotoxic T-cell http://purl.obolibrary.org/obo/CL_0000934 CL:0000936 biolink:Cell early lymphoid progenitor A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. go-plus.json ELP|GMLP|lymphoid-primed multipotent progenitor|LMPP http://purl.obolibrary.org/obo/CL_0000936 CL:0000937 biolink:Cell pre-natural killer cell Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. go-plus.json pre-NK cell http://purl.obolibrary.org/obo/CL_0000937 GO:0015080 biolink:MolecularActivity silver ion transmembrane transporter activity Enables the transfer of silver (Ag) ions from one side of a membrane to the other. go-plus.json silver transporter activity http://purl.obolibrary.org/obo/GO_0015080 CL:0000906 biolink:Cell activated CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative. go-plus.json activated CD8-positive, alpha-beta T lymphocyte|activated CD8-positive, alpha-beta T-cell|activated CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/CL_0000906 GO:0015081 biolink:MolecularActivity sodium ion transmembrane transporter activity Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. go-plus.json sodium transporter activity http://purl.obolibrary.org/obo/GO_0015081 CL:0000908 biolink:Cell CD8-positive, alpha-beta cytokine secreting effector T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. go-plus.json CD8-positive, alpha-beta cytokine secreting effector T-cell|CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte|CD8-positive, alpha-beta cytokine secreting effector T lymphocyte http://purl.obolibrary.org/obo/CL_0000908 GO:0015082 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015082 CL:0000909 biolink:Cell CD8-positive, alpha-beta memory T cell A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell. go-plus.json CD8-positive, alpha-beta memory T-cell|CD8-positive, alpha-beta memory T-lymphocyte|T.8Mem.Sp|CD8-positive, alpha-beta memory T lymphocyte http://purl.obolibrary.org/obo/CL_0000909 CHEBI:134090 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_134090 chebi_ph7_3 CL:0000900 biolink:Cell naive thymus-derived CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. go-plus.json naive thymus-dervied CD8-positive, alpha-beta T lymphocyte|naive CD8+ T cell|T.8Nve.Sp|naive thymus-dervied CD8-positive, alpha-beta T-cell|naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/CL_0000900 CL:0000901 biolink:Cell Tr1 cell CD4-positive alpha-beta T cell with regulatory function that produces IL-10. go-plus.json Tr1 T cell|Tr1 T lymphocyte|T-regulatory T cell type 1|Tr1 T-cell|Tr1 T-lymphocyte http://purl.obolibrary.org/obo/CL_0000901 CHEBI:17608 biolink:ChemicalSubstance D-aldohexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17608 CHEBI:17609 biolink:ChemicalSubstance cortisol 21-acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17609 chebi_ph7_3 CHEBI:17606 biolink:ChemicalSubstance diiodine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17606 chebi_ph7_3 CHEBI:17607 biolink:ChemicalSubstance 1,5-dihydroriboflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17607 chebi_ph7_3 CHEBI:17604 biolink:ChemicalSubstance N(6)-methyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17604 CHEBI:17605 biolink:ChemicalSubstance 2-formylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17605 CHEBI:17602 biolink:ChemicalSubstance 4-aminophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17602 chebi_ph7_3 CHEBI:17600 biolink:ChemicalSubstance hexadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17600 chebi_ph7_3 CHEBI:17601 biolink:ChemicalSubstance 6,7-dimethyl-8-(1-D-ribityl)lumazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17601 GO:0015076 biolink:MolecularActivity obsolete heavy metal ion transporter activity OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. go-plus.json heavy metal ion transporter activity http://purl.obolibrary.org/obo/GO_0015076 GO:0015077 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015077 CHEBI:134085 biolink:ChemicalSubstance 3-hydroxyanthocyanidin cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_134085 GO:0015078 biolink:MolecularActivity proton transmembrane transporter activity Enables the transfer of a proton from one side of a membrane to the other. Reactome:R-HSA-170026|Reactome:R-HSA-917841|Reactome:R-HSA-74723|Reactome:R-HSA-164834|Reactome:R-HSA-1222516 go-plus.json hydrogen ion transmembrane transporter activity|proton transporter activity http://purl.obolibrary.org/obo/GO_0015078 GO:0015079 biolink:MolecularActivity potassium ion transmembrane transporter activity Enables the transfer of potassium ions (K+) from one side of a membrane to the other. RHEA:29463 go-plus.json potassium uptake transmembrane transporter activity|potassium transporter activity|potassium uptake permease activity http://purl.obolibrary.org/obo/GO_0015079 GO:0015072 biolink:MolecularActivity obsolete phosphatidylinositol 3-kinase, class I, catalyst activity OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate. go-plus.json phosphatidylinositol 3-kinase, class I, catalyst activity http://purl.obolibrary.org/obo/GO_0015072 CHEBI:134088 biolink:ChemicalSubstance (2S,3R)-flavan-3-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134088 chebi_ph7_3 GO:0015073 biolink:MolecularActivity obsolete phosphatidylinositol 3-kinase, class I, regulator activity OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate. go-plus.json phosphatidylinositol 3-kinase, class I, regulator activity http://purl.obolibrary.org/obo/GO_0015073 CHEBI:134089 biolink:ChemicalSubstance (2S,3S)-flavan-3-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134089 chebi_ph7_3 GO:0015074 biolink:BiologicalProcess DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0015074 goslim_pir CHEBI:134086 biolink:ChemicalSubstance (2R,3R)-flavan-3-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134086 chebi_ph7_3 GO:0015075 biolink:MolecularActivity ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other. go-plus.json ion transporter activity http://purl.obolibrary.org/obo/GO_0015075 CHEBI:134087 biolink:ChemicalSubstance 3-hydroxyanthocyanidin betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134087 chebi_ph7_3 GO:0015090 biolink:MolecularActivity low-affinity ferric iron ion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity iron transporter activity|low affinity iron ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015090 CL:0000916 biolink:Cell dendritic epidermal T cell A mature gamma-delta T cell located in the epidermis that regulates wound healing. go-plus.json DETC|dendritic epidermal T lymphocyte|dendritic epidermal T-cell|dendritic epidermal T-lymphocyte http://purl.obolibrary.org/obo/CL_0000916 GO:0015091 biolink:MolecularActivity ferric iron transmembrane transporter activity Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015091 GO:0015092 biolink:MolecularActivity high-affinity ferric iron transmembrane transporter activity Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity ferric uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015092 CL:0000918 biolink:Cell Tc2 cell A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. go-plus.json T-cytotoxic T cell type 2|Tc2 T cell|Tc2 T lymphocyte|Th2 CD8-positive T cell|Tc2 T-cell|CD8-positive Th2 cell|Tc2 T-lymphocyte|Th2 non-TFH CD8-positive T cell http://purl.obolibrary.org/obo/CL_0000918 GO:0015093 biolink:MolecularActivity ferrous iron transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. RHEA:28486|Reactome:R-HSA-442368|Reactome:R-HSA-5655760|Reactome:R-HSA-1362417 go-plus.json ferrous iron uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015093 CL:0000910 biolink:Cell cytotoxic T cell A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive. go-plus.json cytotoxic T lymphocyte|cytotoxic T-cell|cytotoxic T-lymphocyte http://purl.obolibrary.org/obo/CL_0000910 CL:0000911 biolink:Cell effector T cell A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response. go-plus.json effector T-cell|effector T-lymphocyte|effector T lymphocyte http://purl.obolibrary.org/obo/CL_0000911 CL:0000912 biolink:Cell helper T cell A effector T cell that provides help in the form of secreted cytokines to other immune cells. go-plus.json helper T-cell|helper T-lymphocyte|helper T lymphocyte|T-helper cell http://purl.obolibrary.org/obo/CL_0000912 CL:0000914 biolink:Cell immature NK T cell An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. go-plus.json immature NK T-cell|immature NK T-lymphocyte|immature NKT cell|immature NK T lymphocyte http://purl.obolibrary.org/obo/CL_0000914 CL:0000915 biolink:Cell CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative. go-plus.json CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte|CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell|CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/CL_0000915 GO:0015087 biolink:MolecularActivity cobalt ion transmembrane transporter activity Enables the transfer of cobalt (Co) ions from one side of a membrane to the other. RHEA:28578 go-plus.json zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|cobalt, zinc uptake permease activity http://purl.obolibrary.org/obo/GO_0015087 GO:0015088 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015088 GO:0015089 biolink:MolecularActivity high-affinity copper ion transmembrane transporter activity Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity copper transporter activity|high affinity copper ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015089 CHEBI:134093 biolink:ChemicalSubstance (acetamidomethyl)phosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134093 chebi_ph7_3 CHEBI:134099 biolink:ChemicalSubstance [(S)-1-acetamidoethyl]phosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134099 chebi_ph7_3 GO:0015083 biolink:MolecularActivity aluminum ion transmembrane transporter activity Enables the transfer of aluminum (Al) ions from one side of a membrane to the other. go-plus.json aluminium ion transporter activity|aluminium resistance permease activity|aluminum resistance permease activity http://purl.obolibrary.org/obo/GO_0015083 GO:0015084 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015084 GO:0015085 biolink:MolecularActivity calcium ion transmembrane transporter activity Enables the transfer of calcium (Ca) ions from one side of a membrane to the other. Reactome:R-HSA-2534359 go-plus.json http://purl.obolibrary.org/obo/GO_0015085 CHEBI:6641 biolink:ChemicalSubstance (S)-magnoflorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_6641 chebi_ph7_3 GO:0015086 biolink:MolecularActivity cadmium ion transmembrane transporter activity Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other. go-plus.json zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|zinc, cadmium uptake permease activity http://purl.obolibrary.org/obo/GO_0015086 CHEBI:134098 biolink:ChemicalSubstance (S)-(1-aminoethyl)phosphonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134098 chebi_ph7_3 GO:0015060 biolink:MolecularActivity obsolete green-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). go-plus.json green-sensitive opsin http://purl.obolibrary.org/obo/GO_0015060 GO:0030699 biolink:MolecularActivity glycine reductase activity Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin. RHEA:12232|EC:1.21.4.2|MetaCyc:RXN-7566|KEGG_REACTION:R07226 go-plus.json acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming) http://purl.obolibrary.org/obo/GO_0030699 GO:0030697 biolink:MolecularActivity S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes. EC:2.1.1.35|RHEA:42712|MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity|tRNA uracil 5-methyltransferase activity|transfer RNA uracil 5-methyltransferase activity|ribothymidyl synthase activity|transfer RNA uracil methylase activity|M5U-methyltransferase activity|RUMT|RUMT activity|tRNA (uracil-5-)-methyltransferase activity|tRNA:m(5)U54-methyltransferase activity|tRNA:m5U54-methyltransferase activity|S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity http://purl.obolibrary.org/obo/GO_0030697 GO:0030698 biolink:MolecularActivity 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria. go-plus.json RUMT http://purl.obolibrary.org/obo/GO_0030698 CHEBI:134068 biolink:ChemicalSubstance (1->4)-6-phospho-alpha-D-glucan polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134068 chebi_ph7_3 GO:0015058 biolink:MolecularActivity obsolete epidermal growth factor-like module containing hormone receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json epidermal growth factor-like module containing hormone receptor activity|EGF-like module containing hormone receptor activity|Egr1 hormone receptor http://purl.obolibrary.org/obo/GO_0015058 GO:0015059 biolink:MolecularActivity obsolete blue-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). go-plus.json blue-sensitive opsin http://purl.obolibrary.org/obo/GO_0015059 GO:0030695 biolink:MolecularActivity GTPase regulator activity Binds to and modulates the activity of a GTPase. go-plus.json small GTPase regulator activity|small GTPase regulatory/interacting protein activity http://purl.obolibrary.org/obo/GO_0030695 GO:0039021 biolink:BiologicalProcess pronephric glomerulus development The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. go-plus.json http://purl.obolibrary.org/obo/GO_0039021 GO:0015054 biolink:MolecularActivity gastrin receptor activity Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. go-plus.json cholecystokinin-B receptor activity http://purl.obolibrary.org/obo/GO_0015054 GO:0030696 biolink:MolecularActivity tRNA (m5U54) methyltransferase activity Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule. go-plus.json RUMT http://purl.obolibrary.org/obo/GO_0030696 GO:0015055 biolink:MolecularActivity secretin receptor activity Combining with secretin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0015055 GO:0039022 biolink:BiologicalProcess pronephric duct development The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0039022 GO:0030693 biolink:MolecularActivity obsolete caspase activity OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue. go-plus.json signaling (initiator) caspase activity|caspase-10 activity|caspase-1 activity|caspase-2 activity|caspase-3 activity|caspase activity|caspase-4 activity|caspase-5 activity|caspase-6 activity|caspase-7 activity|caspase-8 activity|caspase-9 activity|effector caspase activity http://purl.obolibrary.org/obo/GO_0030693 GO:0015056 biolink:MolecularActivity corticotrophin-releasing factor receptor activity Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0015056 GO:0030694 biolink:CellularComponent bacterial-type flagellum basal body, rod The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings. go-plus.json flagellin-based flagellum basal body, rod|flagellar basal body, rod http://purl.obolibrary.org/obo/GO_0030694 GO:0015057 biolink:MolecularActivity thrombin-activated receptor activity A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it. go-plus.json thrombin receptor activity, G-protein coupled|thrombin receptor activity http://purl.obolibrary.org/obo/GO_0015057 GO:0039020 biolink:BiologicalProcess pronephric nephron tubule development The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct. go-plus.json http://purl.obolibrary.org/obo/GO_0039020 GO:0015050 biolink:CellularComponent methane monooxygenase complex A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized. go-plus.json http://purl.obolibrary.org/obo/GO_0015050 GO:0030691 biolink:CellularComponent Noc2p-Noc3p complex A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0030691 CHEBI:6698 biolink:ChemicalSubstance (-)-matairesinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_6698 chebi_ph7_3 GO:0015051 biolink:MolecularActivity obsolete X-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors. go-plus.json X-opioid receptor activity http://purl.obolibrary.org/obo/GO_0015051 GO:0030692 biolink:CellularComponent Noc4p-Nop14p complex A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis. go-plus.json Nop7 complex|Nop7 subcomplex http://purl.obolibrary.org/obo/GO_0030692 CHEBI:6695 biolink:ChemicalSubstance (+)-marmesin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6695 chebi_ph7_3 GO:0039023 biolink:BiologicalProcess pronephric duct morphogenesis The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0039023 CHEBI:134064 biolink:ChemicalSubstance N-oleoylserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_134064 chebi_ph7_3 GO:0015052 biolink:MolecularActivity beta3-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors. go-plus.json beta3 adrenoceptor http://purl.obolibrary.org/obo/GO_0015052 GO:0015053 biolink:MolecularActivity obsolete opsin OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin. go-plus.json opsin http://purl.obolibrary.org/obo/GO_0015053 GO:0030690 biolink:CellularComponent Noc1p-Noc2p complex A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0030690 CHEBI:134065 biolink:ChemicalSubstance N-stearoylserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_134065 chebi_ph7_3 GO:0015070 biolink:MolecularActivity obsolete toxin activity OBSOLETE. Acts as to cause injury to other living organisms. go-plus.json toxin activity http://purl.obolibrary.org/obo/GO_0015070 GO:0015071 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015071 GO:0030688 biolink:CellularComponent preribosome, small subunit precursor A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit. go-plus.json 43S preribosome http://purl.obolibrary.org/obo/GO_0030688 GO:0030689 biolink:CellularComponent Noc complex Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0030689 goslim_pir GO:0030686 biolink:CellularComponent 90S preribosome A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030686 GO:0030687 biolink:CellularComponent preribosome, large subunit precursor A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. go-plus.json 66S preribosome http://purl.obolibrary.org/obo/GO_0030687 GO:0039018 biolink:BiologicalProcess nephrostome development The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0039018 GO:0039019 biolink:BiologicalProcess pronephric nephron development The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros. go-plus.json http://purl.obolibrary.org/obo/GO_0039019 GO:0039016 biolink:BiologicalProcess cell-cell signaling involved in pronephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ. go-plus.json cell-cell signaling involved in pronephric kidney development|cell-cell signalling involved in pronephros development http://purl.obolibrary.org/obo/GO_0039016 CHEBI:134079 biolink:ChemicalSubstance (5Z,8R,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134079 chebi_ph7_3 GO:0039017 biolink:BiologicalProcess pattern specification involved in pronephros development Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate. go-plus.json pattern specification involved in pronephric kidney development http://purl.obolibrary.org/obo/GO_0039017 GO:0015069 biolink:MolecularActivity scyllo-inosamine-4-phosphate amidinotransferase activity Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine. KEGG_REACTION:R03477|MetaCyc:2.1.4.2-RXN|RHEA:13265|EC:2.1.4.2 go-plus.json L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity|L-arginine:inosamine phosphate amidinotransferase activity|inosamine-phosphate amidinotransferase activity|inosamine-P amidinotransferase activity|L-arginine:inosamine-P-amidinotransferase activity http://purl.obolibrary.org/obo/GO_0015069 GO:0030684 biolink:CellularComponent preribosome Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0030684 goslim_pir GO:0039010 biolink:BiologicalProcess specification of pronephric distal tubule identity The process in which the distal tubule of the pronephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0039010 GO:0015065 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015065 GO:0015066 biolink:MolecularActivity alpha-amylase inhibitor activity Binds to and stops, prevents or reduces the activity of alpha-amylase. go-plus.json http://purl.obolibrary.org/obo/GO_0015066 GO:0039011 biolink:BiologicalProcess pronephric proximal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. go-plus.json pronephros proximal tubule morphogenesis http://purl.obolibrary.org/obo/GO_0039011 GO:0030685 biolink:CellularComponent nucleolar preribosome Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0030685 GO:0030682 biolink:BiologicalProcess mitigation of host defenses by symbiont A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json avoidance of host defences|evasion or tolerance of host defenses|evasion or tolerance of defense response of other organism involved in symbiotic interaction|evasion or tolerance of defense response of other organism during symbiotic interaction|avoidance of defenses of other organism involved in symbiotic interaction|evasion or tolerance of defenses of other organism|evasion or tolerance of host defense response|evasion or tolerance of defenses of other organism involved in symbiotic interaction|evasion of other organism defence response|avoidance of defenses of other organism during symbiotic interaction|avoidance of host defenses|evasion of host defence response|evasion or tolerance of defenses of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0030682 GO:0015067 biolink:MolecularActivity amidinotransferase activity Catalysis of the reversible transfer of an amidino group to an acceptor. EC:2.1.4.- go-plus.json transamidinase activity http://purl.obolibrary.org/obo/GO_0015067 GO:0015068 biolink:MolecularActivity glycine amidinotransferase activity Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate. Reactome:R-HSA-71275|MetaCyc:GLYCINE-AMIDINOTRANSFERASE-RXN|RHEA:13201|EC:2.1.4.1 go-plus.json arginine-glycine amidinotransferase activity|L-arginine:glycine amidinotransferase activity|glycine transamidinase activity|arginine-glycine transamidinase activity http://purl.obolibrary.org/obo/GO_0015068 GO:0030683 biolink:BiologicalProcess mitigation of host immune response by virus A process by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json evasion or tolerance by virus of host immune response|viral inhibition of intracellular antiviral response|suppression by virus of host extracellular antiviral response|inhibition of extracellular antiviral response|negative regulation of host intracellular antiviral response by virus|suppression of host intracellular antiviral response by virus|negative regulation by virus of extracellular antiviral response|mitigation by virus of host immune response|suppression by virus of host immune response|evasion by virus of host immune response|suppression by virus of host intracellular antiviral response|negative regulation of host extracellular antiviral response by virus|suppression of host extracellular antiviral response by virus|negative regulation by virus of intracellular antiviral response http://purl.obolibrary.org/obo/GO_0030683 CHEBI:134072 biolink:ChemicalSubstance N-hexadecanoyl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134072 chebi_ph7_3 GO:0030680 biolink:CellularComponent dimeric ribonuclease P complex A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species. go-plus.json dimeric RNase P complex http://purl.obolibrary.org/obo/GO_0030680 GO:0015061 biolink:MolecularActivity obsolete red-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). go-plus.json red-sensitive opsin http://purl.obolibrary.org/obo/GO_0015061 GO:0039014 biolink:BiologicalProcess cell differentiation involved in pronephros development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state. go-plus.json cell differentiation involved in pronephric kidney development http://purl.obolibrary.org/obo/GO_0039014 GO:0039015 biolink:BiologicalProcess cell proliferation involved in pronephros development The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros. go-plus.json cell proliferation involved in pronephric kidney development http://purl.obolibrary.org/obo/GO_0039015 GO:0015062 biolink:MolecularActivity obsolete violet-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). go-plus.json violet-sensitive opsin http://purl.obolibrary.org/obo/GO_0015062 GO:0030681 biolink:CellularComponent multimeric ribonuclease P complex A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species. go-plus.json multimeric RNase P complex http://purl.obolibrary.org/obo/GO_0030681 GO:0039012 biolink:BiologicalProcess pronephric sinus development The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0039012 GO:0015063 biolink:MolecularActivity obsolete long-wave-sensitive opsin OBSOLETE. An opsin with maximal absorption above 500 nm. go-plus.json long-wave-sensitive opsin http://purl.obolibrary.org/obo/GO_0015063 GO:0039013 biolink:BiologicalProcess pronephric distal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. go-plus.json http://purl.obolibrary.org/obo/GO_0039013 GO:0015064 biolink:MolecularActivity obsolete UV-sensitive opsin OBSOLETE. An opsin with maximal absorption below 400 nm. go-plus.json UV-sensitive opsin http://purl.obolibrary.org/obo/GO_0015064 GO:0030679 biolink:CellularComponent cyanelle ribonuclease P complex A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules. go-plus.json cyanelle RNase P complex http://purl.obolibrary.org/obo/GO_0030679 GO:0030677 biolink:CellularComponent ribonuclease P complex A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs. go-plus.json RNase P complex http://purl.obolibrary.org/obo/GO_0030677 goslim_pir GO:0030678 biolink:CellularComponent mitochondrial ribonuclease P complex A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans. go-plus.json mitochondrial RNase P complex http://purl.obolibrary.org/obo/GO_0030678 GO:0030675 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030675 GO:0030676 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030676 GO:0039007 biolink:BiologicalProcess pronephric nephron morphogenesis The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros. go-plus.json http://purl.obolibrary.org/obo/GO_0039007 GO:0039008 biolink:BiologicalProcess pronephric nephron tubule morphogenesis The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0039008 GO:0039005 biolink:BiologicalProcess specification of pronephric tubule identity The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0039005 GO:0039006 biolink:BiologicalProcess pronephric nephron tubule formation The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros. go-plus.json pronephric tubule formation|pronephros tubule formation http://purl.obolibrary.org/obo/GO_0039006 GO:0015036 biolink:MolecularActivity disulfide oxidoreductase activity Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds. Reactome:R-HSA-1222655|Reactome:R-HSA-264997|Reactome:R-HSA-1222690|Reactome:R-HSA-1222644|Reactome:R-HSA-1222417 go-plus.json disulphide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0015036 GO:0015037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015037 GO:0015038 biolink:MolecularActivity glutathione disulfide oxidoreductase activity Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor. Reactome:R-HSA-111746 go-plus.json glutaredoxin|glutathione disulphide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0015038 GO:0039009 biolink:BiologicalProcess rectal diverticulum development The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior. go-plus.json pronephric rectal diverticulum development http://purl.obolibrary.org/obo/GO_0039009 GO:0015039 biolink:MolecularActivity NADPH-adrenodoxin reductase activity Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+. RHEA:42312|EC:1.18.1.6|MetaCyc:RXN-13685 go-plus.json NADPH:adrenodoxin oxidoreductase activity|adrenodoxin-type ferredoxin reductase activity|adrenodoxin reductase activity http://purl.obolibrary.org/obo/GO_0015039 GO:0015032 biolink:BiologicalProcess obsolete storage protein import into fat body OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life. go-plus.json storage protein import by fat body cells|storage protein transport into fat body cells|storage protein import into fat body cells|fat body metabolic process|storage protein uptake into fat body cells|fat body storage protein uptake|import of storage protein into fat body|fat body metabolism http://purl.obolibrary.org/obo/GO_0015032 GO:0030673 biolink:CellularComponent axolemma The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness. NIF_Subcellular:sao250772229|Wikipedia:Axolemma go-plus.json axonal membrane http://purl.obolibrary.org/obo/GO_0030673 GO:0030674 biolink:MolecularActivity protein-macromolecule adaptor activity The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid. go-plus.json protein-protein adaptor|protein binding, bridging http://purl.obolibrary.org/obo/GO_0030674 goslim_generic|goslim_chembl|goslim_yeast GO:0015033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015033 CHEBI:134041 biolink:ChemicalSubstance N-octadecanoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134041 chebi_ph7_3 GO:0015034 biolink:MolecularActivity obsolete cytochrome P450 activity OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer. go-plus.json cytochrome P450 activity http://purl.obolibrary.org/obo/GO_0015034 GO:0030671 biolink:CellularComponent clathrin-coated phagocytic vesicle membrane The lipid bilayer surrounding a clathrin-coated phagocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030671 GO:0015035 biolink:MolecularActivity protein-disulfide reductase activity Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds. MetaCyc:DISULFOXRED-RXN|Reactome:R-HSA-1307802|Reactome:R-HSA-3299753 go-plus.json protein disulfide oxidoreductase activity|haem lyase disulphide oxidoreductase activity|protein disulphide oxidoreductase activity|heme lyase disulfide oxidoreductase activity|protein disulfide-oxidoreductase activity|peptide disulphide oxidoreductase activity|peptide disulfide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0015035 GO:0030672 biolink:CellularComponent synaptic vesicle membrane The lipid bilayer surrounding a synaptic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030672 goslim_synapse GO:0039003 biolink:BiologicalProcess pronephric field specification The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop. go-plus.json pronephric kidney field specification http://purl.obolibrary.org/obo/GO_0039003 GO:0030670 biolink:CellularComponent phagocytic vesicle membrane The lipid bilayer surrounding a phagocytic vesicle. go-plus.json phagosome membrane http://purl.obolibrary.org/obo/GO_0030670 GO:0039004 biolink:BiologicalProcess specification of pronephric proximal tubule identity The process in which the proximal tubule of the pronephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0039004 CHEBI:134045 biolink:ChemicalSubstance polychlorinated dibenzodioxines and related compounds go-plus.json http://purl.obolibrary.org/obo/CHEBI_134045 GO:0015030 biolink:CellularComponent Cajal body A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. Wikipedia:Cajal_body|NIF_Subcellular:nlx_subcell_090901 go-plus.json Gemini of coiled bodies|Gems|coiled body http://purl.obolibrary.org/obo/GO_0015030 CHEBI:134042 biolink:ChemicalSubstance N-[(9Z)-hexadecenoyl]glycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134042 chebi_ph7_3 GO:0015031 biolink:BiologicalProcess protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json enzyme transport http://purl.obolibrary.org/obo/GO_0015031 goslim_yeast|goslim_pir|goslim_generic|goslim_chembl CHEBI:134043 biolink:ChemicalSubstance phenylureas go-plus.json http://purl.obolibrary.org/obo/CHEBI_134043 GO:0030668 biolink:CellularComponent merozoite dense granule membrane The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites. go-plus.json http://purl.obolibrary.org/obo/GO_0030668 GO:0030669 biolink:CellularComponent clathrin-coated endocytic vesicle membrane The lipid bilayer surrounding a clathrin-coated endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030669 GO:0030666 biolink:CellularComponent endocytic vesicle membrane The lipid bilayer surrounding an endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030666 GO:0030667 biolink:CellularComponent secretory granule membrane The lipid bilayer surrounding a secretory granule. go-plus.json secretory vesicle membrane http://purl.obolibrary.org/obo/GO_0030667 GO:0030664 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030664 GO:0030665 biolink:CellularComponent clathrin-coated vesicle membrane The lipid bilayer surrounding a clathrin-coated vesicle. go-plus.json clathrin coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030665 OBO:GOCHE_59897 biolink:OntologyClass substance with EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_59897 3_STAR CHEBI:134059 biolink:ChemicalSubstance N-palmitoylserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_134059 chebi_ph7_3 CHEBI:134057 biolink:ChemicalSubstance (4Z,7Z,11E,13Z,16Z,19Z)-10-hydroperoxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134057 chebi_ph7_3 CHEBI:134058 biolink:ChemicalSubstance N-palmitoyl dopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134058 chebi_ph7_3 GO:0015047 biolink:MolecularActivity NADPH-cytochrome-c2 reductase activity Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2. RHEA:15237|EC:1.6.2.5|MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN go-plus.json cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)|NADPH:ferricytochrome-c2 oxidoreductase activity|reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate) http://purl.obolibrary.org/obo/GO_0015047 GO:0015048 biolink:MolecularActivity phthalate dioxygenase reductase activity Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems. go-plus.json http://purl.obolibrary.org/obo/GO_0015048 GO:0015049 biolink:MolecularActivity methane monooxygenase activity Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O. UM-BBD_enzymeID:e0007|EC:1.14.13.25|MetaCyc:METHANE-MONOOXYGENASE-RXN|KEGG_REACTION:R01143|KEGG_REACTION:R01142 go-plus.json methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methane hydroxylase activity http://purl.obolibrary.org/obo/GO_0015049 GO:0030662 biolink:CellularComponent coated vesicle membrane The lipid bilayer surrounding a coated vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030662 CHEBI:134051 biolink:ChemicalSubstance (8R,9E,11Z,14Z)-8-hydroperoxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134051 chebi_ph7_3 GO:0015043 biolink:MolecularActivity leghemoglobin reductase activity Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin. EC:1.6.2.6|MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN go-plus.json ferric leghemoglobin reductase activity|NAD(P)H:ferrileghemoglobin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0015043 GO:0015044 biolink:MolecularActivity rubredoxin-NAD+ reductase activity Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+. MetaCyc:RUBREDOXIN--NAD+-REDUCTASE-RXN|EC:1.18.1.1|RHEA:18597 go-plus.json NADH--rubredoxin oxidoreductase activity|rubredoxin:NAD+ oxidoreductase activity|DPNH-rubredoxin reductase activity|NADH:rubredoxin reductase activity|dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity|rubredoxin--NAD reductase activity|NADH:rubredoxin oxidoreductase activity|reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity|rubredoxin--nicotinamide adenine dinucleotide reductase activity|NADH--rubredoxin reductase activity http://purl.obolibrary.org/obo/GO_0015044 GO:0030663 biolink:CellularComponent COPI-coated vesicle membrane The lipid bilayer surrounding a COPI-coated vesicle. go-plus.json COPI coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030663 CHEBI:134052 biolink:ChemicalSubstance (8Z,11Z,14Z)-10-hydroperoxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134052 chebi_ph7_3 GO:0015045 biolink:MolecularActivity rubredoxin-NAD(P)+ reductase activity Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+. EC:1.18.1.4|MetaCyc:RUBREDOXIN--NADP+-REDUCTASE-RXN go-plus.json rubredoxin:NAD(P)+ oxidoreductase activity|NADPH:rubredoxin reductase activity|NAD(P)H--rubredoxin oxidoreductase activity|rubredoxin--nicotinamide adenine activity|NAD(P)--rubredoxin oxidoreductase activity|rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity|dinucleotide phosphate reductase activity http://purl.obolibrary.org/obo/GO_0015045 GO:0030660 biolink:CellularComponent Golgi-associated vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. go-plus.json Golgi vesicle membrane http://purl.obolibrary.org/obo/GO_0030660 GO:0015046 biolink:MolecularActivity rubredoxin-NADP+ reductase activity Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+. RHEA:13949|EC:1.18.1.4 go-plus.json http://purl.obolibrary.org/obo/GO_0015046 GO:0030661 biolink:CellularComponent chitosome membrane The lipid bilayer surrounding a chitosome. go-plus.json http://purl.obolibrary.org/obo/GO_0030661 CHEBI:134055 biolink:ChemicalSubstance (9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134055 chebi_ph7_3 CHEBI:134056 biolink:ChemicalSubstance (5Z,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134056 chebi_ph7_3 GO:0015040 biolink:MolecularActivity obsolete electron transfer flavoprotein, group I OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway. go-plus.json electron transfer flavoprotein, group I http://purl.obolibrary.org/obo/GO_0015040 GO:0015041 biolink:MolecularActivity obsolete electron transfer flavoprotein, group II OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation. go-plus.json electron transfer flavoprotein, group II http://purl.obolibrary.org/obo/GO_0015041 CHEBI:134053 biolink:ChemicalSubstance (8Z,12E,14Z)-11-hydroperoxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134053 chebi_ph7_3 GO:0015042 biolink:MolecularActivity trypanothione-disulfide reductase activity Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide. MetaCyc:1.8.1.12-RXN|EC:1.8.1.12|RHEA:16757 go-plus.json trypanothione-disulphide reductase activity|N(1),N(8)-bis(glutathionyl)spermidine reductase activity|trypanothione reductase activity|trypanothione:NADP+ oxidoreductase activity|NADPH:trypanothione oxidoreductase activity|N1,N8-bis(glutathionyl)spermidine reductase activity http://purl.obolibrary.org/obo/GO_0015042 CHEBI:134054 biolink:ChemicalSubstance (5Z,8R,9Z,11Z,14Z)-8,9-epoxyicosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134054 chebi_ph7_3 CHEBI:42630 biolink:ChemicalSubstance propylbenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_42630 chebi_ph7_3 CHEBI:17668 biolink:ChemicalSubstance ribonucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17668 CHEBI:17666 biolink:ChemicalSubstance L-ribulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17666 CHEBI:17667 biolink:ChemicalSubstance 3-hydroxy-3-methyl-2-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17667 CHEBI:17664 biolink:ChemicalSubstance alkylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_17664 chebi_ph7_3 CHEBI:17665 biolink:ChemicalSubstance alpha-D-glucose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17665 CHEBI:17663 biolink:ChemicalSubstance (R)-3-[(R)-3-hydroxybutanoyloxy]butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17663 CHEBI:17660 biolink:ChemicalSubstance N(6)-dimethylallyladenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17660 chebi_ph7_3 CHEBI:17661 biolink:ChemicalSubstance GDP-6-deoxy-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17661 CHEBI:27007 biolink:ChemicalSubstance tin atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27007 chebi_ph7_3 CHEBI:27008 biolink:ChemicalSubstance tin molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_27008 CHEBI:27001 biolink:ChemicalSubstance thymidine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27001 CHEBI:42626 biolink:ChemicalSubstance glycyl-AMP zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_42626 chebi_ph7_3 CHEBI:17659 biolink:ChemicalSubstance UDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17659 CHEBI:17658 biolink:ChemicalSubstance tylosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17658 CHEBI:17655 biolink:ChemicalSubstance 4-hydroxy-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17655 CHEBI:17656 biolink:ChemicalSubstance (R)-mandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17656 CHEBI:17654 biolink:ChemicalSubstance electron acceptor go-plus.json http://purl.obolibrary.org/obo/CHEBI_17654 CHEBI:17652 biolink:ChemicalSubstance 3-hydroxy-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17652 CHEBI:17650 biolink:ChemicalSubstance cortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17650 chebi_ph7_3 CHEBI:17690 biolink:ChemicalSubstance (5-L-glutamyl)-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17690 CL:0000985 biolink:Cell IgG plasma cell A fully differentiated plasma cell that secretes IgG. go-plus.json http://purl.obolibrary.org/obo/CL_0000985 CL:0000986 biolink:Cell IgM plasma cell A fully differentiated plasma cell that secretes IgM. go-plus.json http://purl.obolibrary.org/obo/CL_0000986 GO:0040001 biolink:BiologicalProcess establishment of mitotic spindle localization The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs. go-plus.json mitotic spindle positioning|establishment of mitotic spindle localisation|spindle positioning involved in mitotic cell cycle|mitotic spindle positioning or orientation|mitotic spindle positioning and orientation|spindle positioning during mitosis http://purl.obolibrary.org/obo/GO_0040001 CL:0000987 biolink:Cell IgA plasma cell A fully differentiated plasma cell that secretes IgA. go-plus.json http://purl.obolibrary.org/obo/CL_0000987 GO:0040002 biolink:BiologicalProcess collagen and cuticulin-based cuticle development Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans. go-plus.json collagen and cuticulin-based cuticle biosynthetic process|collagen and cuticulin-based cuticle anabolism|collagen and cuticulin-based cuticle synthesis|collagen and cuticulin-based cuticle formation http://purl.obolibrary.org/obo/GO_0040002 CL:0000988 biolink:Cell hematopoietic cell A cell of a hematopoietic lineage. go-plus.json hemopoietic cell|haematopoietic cell|haemopoietic cell http://purl.obolibrary.org/obo/CL_0000988 CL:0000989 biolink:Cell CD11c-low plasmacytoid dendritic cell CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0000989 GO:0040007 biolink:BiologicalProcess growth The increase in size or mass of an entire organism, a part of an organism or a cell. go-plus.json non-developmental growth|growth pattern http://purl.obolibrary.org/obo/GO_0040007 gocheck_do_not_annotate|goslim_plant|goslim_pir|goslim_generic|goslim_chembl GO:0040008 biolink:BiologicalProcess regulation of growth Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. go-plus.json http://purl.obolibrary.org/obo/GO_0040008 GO:0040009 biolink:BiologicalProcess regulation of growth rate Any process that modulates the rate of growth of all or part of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0040009 CL:0000980 biolink:Cell plasmablast An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. go-plus.json CD27-positive, CD38-positive, CD20-negative B cell|CD20-negative B cell http://purl.obolibrary.org/obo/CL_0000980 CL:0000981 biolink:Cell double negative memory B cell A memory B cell with the phenotype IgD-negative and CD27-negative. go-plus.json double negative memory B-cell|double negative memory B-lymphocyte|dn memory B cell|dn memory B lymphocyte|double negative memory B lymphocyte|dn memory B-cell|dn memory B-lymphocyte http://purl.obolibrary.org/obo/CL_0000981 GO:0040003 biolink:BiologicalProcess chitin-based cuticle development Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster. go-plus.json chitin-based cuticle anabolism|chitin-based cuticle synthesis|chitin-based cuticle formation|chitin-based cuticle biosynthetic process http://purl.obolibrary.org/obo/GO_0040003 GO:0040004 biolink:BiologicalProcess collagen and cuticulin-based cuticle attachment to epithelium Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans. go-plus.json cuticular attachment to epithelium http://purl.obolibrary.org/obo/GO_0040004 CL:0000982 biolink:Cell IgG plasmablast A plasmablast that secretes IgG. go-plus.json http://purl.obolibrary.org/obo/CL_0000982 GO:0040005 biolink:BiologicalProcess chitin-based cuticle attachment to epithelium Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster. go-plus.json cuticular attachment to epithelium http://purl.obolibrary.org/obo/GO_0040005 CL:0000983 biolink:Cell IgM plasmablast A plasmablast that secretes IgM. go-plus.json http://purl.obolibrary.org/obo/CL_0000983 CHEBI:17688 biolink:ChemicalSubstance (S)-nicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17688 GO:0040006 biolink:BiologicalProcess obsolete protein-based cuticle attachment to epithelium OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it. go-plus.json cuticular attachment to epithelium|protein-based cuticle attachment to epithelium http://purl.obolibrary.org/obo/GO_0040006 CL:0000984 biolink:Cell IgA plasmablast A plasmablast that secretes IgA. go-plus.json http://purl.obolibrary.org/obo/CL_0000984 CHEBI:17689 biolink:ChemicalSubstance sphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17689 CHEBI:17687 biolink:ChemicalSubstance glycocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17687 CHEBI:17684 biolink:ChemicalSubstance N-formyl-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17684 chebi_ph7_3 CHEBI:17685 biolink:ChemicalSubstance 3-hydroxyquinine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17685 CHEBI:17682 biolink:ChemicalSubstance benzoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17682 chebi_ph7_3 CHEBI:17683 biolink:ChemicalSubstance UDP-L-iduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17683 CHEBI:17680 biolink:ChemicalSubstance D-glucose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17680 CHEBI:17681 biolink:ChemicalSubstance pyridine-2,6-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17681 chebi_ph7_3 GO:0040010 biolink:BiologicalProcess positive regulation of growth rate Any process that increases the rate of growth of all or part of an organism. go-plus.json up-regulation of growth rate|upregulation of growth rate|up regulation of growth rate|activation of growth rate|stimulation of growth rate http://purl.obolibrary.org/obo/GO_0040010 GO:0040011 biolink:BiologicalProcess locomotion Self-propelled movement of a cell or organism from one location to another. go-plus.json http://purl.obolibrary.org/obo/GO_0040011 goslim_chembl|goslim_pir|goslim_generic GO:0040012 biolink:BiologicalProcess regulation of locomotion Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0040012 GO:0040013 biolink:BiologicalProcess negative regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. go-plus.json downregulation of locomotion|down regulation of locomotion|inhibition of locomotion|down-regulation of locomotion http://purl.obolibrary.org/obo/GO_0040013 GO:0040018 biolink:BiologicalProcess positive regulation of multicellular organism growth Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. go-plus.json positive regulation of body growth|positive regulation of body size http://purl.obolibrary.org/obo/GO_0040018 GO:0040019 biolink:BiologicalProcess positive regulation of embryonic development Any process that activates or increases the frequency, rate or extent of embryonic development. go-plus.json up regulation of embryonic development|activation of embryonic development|stimulation of embryonic development|up-regulation of embryonic development|upregulation of embryonic development http://purl.obolibrary.org/obo/GO_0040019 CL:0000990 biolink:Cell conventional dendritic cell Conventional dendritic cell is a dendritic cell that is CD11c-high. go-plus.json dendritic reticular cell|interdigitating cell|type 1 DC|DC1|veiled cell|cDC http://purl.obolibrary.org/obo/CL_0000990 GO:0040014 biolink:BiologicalProcess regulation of multicellular organism growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. go-plus.json regulation of body size|regulation of body growth http://purl.obolibrary.org/obo/GO_0040014 CHEBI:17679 biolink:ChemicalSubstance 5-hydroxybenzimidazolylcob(I)amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17679 CL:0000992 biolink:Cell immature CD11c-low plasmacytoid dendritic cell Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low. go-plus.json http://purl.obolibrary.org/obo/CL_0000992 GO:0040015 biolink:BiologicalProcess negative regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. go-plus.json negative regulation of body growth|negative regulation of body size http://purl.obolibrary.org/obo/GO_0040015 CL:0000993 biolink:Cell mature CD11c-low plasmacytoid dendritic cell Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0000993 GO:0040016 biolink:BiologicalProcess embryonic cleavage The first few specialized divisions of an activated animal egg. go-plus.json http://purl.obolibrary.org/obo/GO_0040016 CHEBI:17677 biolink:ChemicalSubstance CTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17677 GO:0040017 biolink:BiologicalProcess positive regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. go-plus.json upregulation of locomotion|stimulation of locomotion|up-regulation of locomotion|activation of locomotion|up regulation of locomotion http://purl.obolibrary.org/obo/GO_0040017 CL:0000995 biolink:Cell CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor go-plus.json CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid http://purl.obolibrary.org/obo/CL_0000995 CHEBI:17678 biolink:ChemicalSubstance 2'-hydroxyformononetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17678 CHEBI:17675 biolink:ChemicalSubstance Watasenia luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17675 CHEBI:17676 biolink:ChemicalSubstance 2-(beta-D-glucopyranosyluronic acid)-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17676 CHEBI:17671 biolink:ChemicalSubstance 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17671 CHEBI:17672 biolink:ChemicalSubstance carbamoyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17672 CHEBI:17670 biolink:ChemicalSubstance 1,2-diacyl-3-O-(alpha-D-glucosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17670 chebi_ph7_3 NCBITaxon:5302 biolink:OrganismalEntity Agaricomycotina go-plus.json Hymenomycetes http://purl.obolibrary.org/obo/NCBITaxon_5302 CL:0000963 biolink:Cell Bm3-delta B cell A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. go-plus.json Bm3-delta B-lymphocyte|Bm3-delta B lymphocyte|Bm3-delta B-cell http://purl.obolibrary.org/obo/CL_0000963 GO:0040021 biolink:BiologicalProcess hermaphrodite germ-line sex determination The determination of sex and sexual phenotype in the germ line of a hermaphrodite. go-plus.json http://purl.obolibrary.org/obo/GO_0040021 GO:0040022 biolink:BiologicalProcess feminization of hermaphroditic germ-line The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite. go-plus.json http://purl.obolibrary.org/obo/GO_0040022 CL:0000964 biolink:Cell Bm2' B cell A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. go-plus.json Bm2-prime B-lymphocyte|Bm2' B-cell|Bm2-prime B cell|germinal center founder cell|Bm2' B lymphocyte http://purl.obolibrary.org/obo/CL_0000964 CL:0000965 biolink:Cell Bm3 B cell A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. go-plus.json Bm3 B lymphocyte|centroblast|Bm3 B-cell|Bm3 B-lymphocyte http://purl.obolibrary.org/obo/CL_0000965 GO:0040023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0040023 CL:0000966 biolink:Cell Bm4 B cell A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. go-plus.json Bm4 B lymphocyte|centrocyte|Bm4 B-cell|Bm4 B-lymphocyte http://purl.obolibrary.org/obo/CL_0000966 GO:0040024 biolink:BiologicalProcess dauer larval development The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. go-plus.json http://purl.obolibrary.org/obo/GO_0040024 CL:0000967 biolink:Cell Bm5 B cell A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. go-plus.json Bm5 B lymphocyte|Bm5 B-cell|Bm5 B-lymphocyte http://purl.obolibrary.org/obo/CL_0000967 CL:0000968 biolink:Cell Be cell A mature B cell that produces cytokines that can influence CD4 T cell differentiation. go-plus.json effector B-lymphocyte|B effector cell|effector B cell|effector B lymphocyte|effector B-cell http://purl.obolibrary.org/obo/CL_0000968 GO:0040020 biolink:BiologicalProcess regulation of meiotic nuclear division Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. go-plus.json regulation of meiosis http://purl.obolibrary.org/obo/GO_0040020 GO:0040029 biolink:BiologicalProcess regulation of gene expression, epigenetic Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. go-plus.json http://purl.obolibrary.org/obo/GO_0040029 goslim_plant CHEBI:17628 biolink:ChemicalSubstance 2-aminoacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17628 CHEBI:17626 biolink:ChemicalSubstance citraconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17626 CHEBI:17627 biolink:ChemicalSubstance ferroheme b go-plus.json http://purl.obolibrary.org/obo/CHEBI_17627 GO:0040025 biolink:BiologicalProcess vulval development The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. go-plus.json http://purl.obolibrary.org/obo/GO_0040025 CHEBI:17624 biolink:ChemicalSubstance dolichyl beta-D-mannosyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17624 GO:0040026 biolink:BiologicalProcess positive regulation of vulval development Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. go-plus.json activation of vulval development|up regulation of vulval development|upregulation of vulval development|up-regulation of vulval development|stimulation of vulval development http://purl.obolibrary.org/obo/GO_0040026 CL:0000960 biolink:Cell T3 B cell A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). go-plus.json transitional stage 3 B cell|T3 B-cell|T3 B-lymphocyte|T3 B lymphocyte|An1 B cell http://purl.obolibrary.org/obo/CL_0000960 CHEBI:17625 biolink:ChemicalSubstance dUTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17625 GO:0040027 biolink:BiologicalProcess negative regulation of vulval development Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. go-plus.json downregulation of vulval development|down regulation of vulval development|inhibition of vulval development|down-regulation of vulval development http://purl.obolibrary.org/obo/GO_0040027 CL:0000961 biolink:Cell Bm1 B cell A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. go-plus.json Bm1 B-cell|Bm1 B-lymphocyte|Bm1 B lymphocyte http://purl.obolibrary.org/obo/CL_0000961 CHEBI:17622 biolink:ChemicalSubstance dUMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17622 CL:0000962 biolink:Cell Bm2 B cell A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. go-plus.json Bm2 B lymphocyte|Bm2 B-cell|Bm2 B-lymphocyte http://purl.obolibrary.org/obo/CL_0000962 CHEBI:17623 biolink:ChemicalSubstance cyclomaltodextrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17623 chebi_ph7_3 GO:0040028 biolink:BiologicalProcess regulation of vulval development Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. go-plus.json http://purl.obolibrary.org/obo/GO_0040028 CHEBI:17620 biolink:ChemicalSubstance ferulic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17620 CHEBI:17621 biolink:ChemicalSubstance FMN go-plus.json http://purl.obolibrary.org/obo/CHEBI_17621 GO:0040032 biolink:BiologicalProcess post-embryonic body morphogenesis The process in which the anatomical structures of the post-embryonic soma are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0040032 CL:0000974 biolink:Cell long lived plasma cell A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. go-plus.json http://purl.obolibrary.org/obo/CL_0000974 CL:0000975 biolink:Cell short lived plasma cell A fully differentiated plasma cell that lives for months. go-plus.json http://purl.obolibrary.org/obo/CL_0000975 GO:0040033 biolink:BiologicalProcess negative regulation of translation, ncRNA-mediated Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein. go-plus.json down-regulation of mRNA translation, ncRNA-mediated|downregulation of mRNA translation, ncRNA-mediated|down regulation of mRNA translation, ncRNA-mediated|inhibition of mRNA translation, ncRNA-mediated http://purl.obolibrary.org/obo/GO_0040033 GO:0040034 biolink:BiologicalProcess regulation of development, heterochronic Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. go-plus.json temporal regulation of development|heterochronic regulation of development|developmental timing http://purl.obolibrary.org/obo/GO_0040034 CL:0000976 biolink:Cell IgA short lived plasma cell A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system. go-plus.json http://purl.obolibrary.org/obo/CL_0000976 GO:0040035 biolink:BiologicalProcess hermaphrodite genitalia development The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures. go-plus.json http://purl.obolibrary.org/obo/GO_0040035 CL:0000977 biolink:Cell IgG short lived plasma cell A short lived plasma cell that secretes IgG. go-plus.json http://purl.obolibrary.org/obo/CL_0000977 CL:0000978 biolink:Cell IgM short lived plasma cell A short lived plasma cell that secretes IgM. go-plus.json http://purl.obolibrary.org/obo/CL_0000978 CL:0000979 biolink:Cell IgG memory B cell An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface. go-plus.json IgG memory B lymphocyte|memory IgG B-cell|memory IgG B-lymphocyte|memory IgG B cell|IgG memory B-cell|memory IgG B lymphocyte|IgG memory B-lymphocyte http://purl.obolibrary.org/obo/CL_0000979 GO:0040030 biolink:BiologicalProcess regulation of molecular function, epigenetic Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya. go-plus.json regulation of protein activity, epigenetic http://purl.obolibrary.org/obo/GO_0040030 CHEBI:17619 biolink:ChemicalSubstance 4-(3-methylbut-2-enyl)-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_17619 GO:0040031 biolink:BiologicalProcess snRNA modification The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0040031 CHEBI:17617 biolink:ChemicalSubstance L-fuculose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17617 chebi_ph7_3 CHEBI:17618 biolink:ChemicalSubstance bis-D-fructose 2',1:2,1'-dianhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_17618 chebi_ph7_3 CHEBI:17615 biolink:ChemicalSubstance 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17615 chebi_ph7_3 CHEBI:17616 biolink:ChemicalSubstance all-trans-retinyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17616 chebi_ph7_3 GO:0040036 biolink:BiologicalProcess regulation of fibroblast growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. go-plus.json regulation of FGF receptor signaling pathway|regulation of FGFR signaling pathway|regulation of FGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0040036 CL:0000970 biolink:Cell unswitched memory B cell An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. go-plus.json IgD+ memory B cell|unswitched memory B-cell|unswitched memory B-lymphocyte|non-class-switched memory B cell|unswitched memory B lymphocyte http://purl.obolibrary.org/obo/CL_0000970 CHEBI:17613 biolink:ChemicalSubstance all-trans-heptaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17613 CHEBI:17614 biolink:ChemicalSubstance 5-methyltetrahydropteroyltri-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17614 GO:0040037 biolink:BiologicalProcess negative regulation of fibroblast growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. go-plus.json inhibition of fibroblast growth factor receptor signaling pathway|negative regulation of FGF receptor signalling pathway|negative regulation of FGFR signaling pathway|down regulation of fibroblast growth factor receptor signaling pathway|downregulation of fibroblast growth factor receptor signaling pathway|down-regulation of fibroblast growth factor receptor signaling pathway|negative regulation of FGF receptor signaling pathway http://purl.obolibrary.org/obo/GO_0040037 CL:0000971 biolink:Cell IgM memory B cell An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative. go-plus.json memory IgM B-cell|IgM memory B-cell|memory IgM B-lymphocyte|IgM memory B-lymphocyte|memory IgM B cell|memory IgM B lymphocyte|IgM memory B lymphocyte http://purl.obolibrary.org/obo/CL_0000971 CL:0000972 biolink:Cell class switched memory B cell A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. go-plus.json class switched memory B-lymphocyte|class switched memory B lymphocyte|class switched memory B-cell http://purl.obolibrary.org/obo/CL_0000972 GO:0040038 biolink:BiologicalProcess polar body extrusion after meiotic divisions The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0040038 CHEBI:17611 biolink:ChemicalSubstance 3-hydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17611 chebi_ph7_3 CL:0000973 biolink:Cell IgA memory B cell A class switched memory B cell that expresses IgA. go-plus.json IgA memory B lymphocyte|memory IgA B cell|memory IgA B lymphocyte|IgA memory B-cell|IgA memory B-lymphocyte|memory IgA B-cell|memory IgA B-lymphocyte http://purl.obolibrary.org/obo/CL_0000973 GO:0040039 biolink:BiologicalProcess inductive cell migration Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0040039 CHEBI:17612 biolink:ChemicalSubstance (3,4-dihydroxyphenyl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17612 chebi_ph7_3 CHEBI:17610 biolink:ChemicalSubstance 3-nitroacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17610 CL:0000949 biolink:Cell IgD plasmablast A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult. go-plus.json http://purl.obolibrary.org/obo/CL_0000949 CL:0000941 biolink:Cell thymic conventional dendritic cell A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0000941 CL:0000942 biolink:Cell thymic plasmacytoid dendritic cell A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0000942 CL:0000943 biolink:Cell Be1 Cell A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. go-plus.json B effector cell type 1|B effector 1 cell http://purl.obolibrary.org/obo/CL_0000943 CL:0000944 biolink:Cell Be2 cell A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6. go-plus.json B effector cell type 2|B effector 2 cell http://purl.obolibrary.org/obo/CL_0000944 RO:0002630 biolink:OntologyClass directly negatively regulates Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2. RO:0002630 go-plus.json http://purl.obolibrary.org/obo/RO_0002630 CL:0000945 biolink:Cell lymphocyte of B lineage A lymphocyte of B lineage with the commitment to express an immunoglobulin complex. go-plus.json http://purl.obolibrary.org/obo/CL_0000945 GO:0040040 biolink:BiologicalProcess thermosensory behavior Behavior that is dependent upon the sensation of temperature. go-plus.json thermosensory behaviour|behavioral response to temperature stimulus|behavioural response to temperature stimulus http://purl.obolibrary.org/obo/GO_0040040 CL:0000946 biolink:Cell antibody secreting cell A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin. go-plus.json http://purl.obolibrary.org/obo/CL_0000946 CL:0000947 biolink:Cell IgE plasma cell A long lived plasma cell that secretes IgE. go-plus.json http://purl.obolibrary.org/obo/CL_0000947 CL:0000948 biolink:Cell IgE memory B cell A class switched memory B cell that expresses IgE on the cell surface. go-plus.json memory IgE B cell|memory IgE B lymphocyte|IgE memory B-cell|IgE memory B-lymphocyte|memory IgE B-cell|IgE memory B lymphocyte|memory IgE B-lymphocyte http://purl.obolibrary.org/obo/CL_0000948 CHEBI:17648 biolink:ChemicalSubstance N-adenylyl-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17648 CHEBI:17649 biolink:ChemicalSubstance hydroxymalonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17649 chebi_ph7_3 CHEBI:17646 biolink:ChemicalSubstance mevaldic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17646 CHEBI:17647 biolink:ChemicalSubstance 2-dehydro-3-deoxy-L-arabinonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17647 CL:0000940 biolink:Cell mucosal invariant T cell An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. go-plus.json mucosal invariant T-cell|mucosal invariant T-lymphocyte|mucosal invariant T lymphocyte http://purl.obolibrary.org/obo/CL_0000940 CHEBI:17645 biolink:ChemicalSubstance 4-acetamidobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17645 CHEBI:17642 biolink:ChemicalSubstance pentachlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17642 CHEBI:17643 biolink:ChemicalSubstance 9-riburonosylhypoxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17643 CHEBI:17640 biolink:ChemicalSubstance 3-(indol-3-yl)pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17640 chebi_ph7_3 RO:0002629 biolink:OntologyClass directly positively regulates Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2. RO:0002629 go-plus.json http://purl.obolibrary.org/obo/RO_0002629 CL:0000952 biolink:Cell preBCR-positive large pre-B-II cell An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface. go-plus.json http://purl.obolibrary.org/obo/CL_0000952 CL:0000953 biolink:Cell preBCR-negative large pre-B-II cell A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. go-plus.json http://purl.obolibrary.org/obo/CL_0000953 CL:0000954 biolink:Cell small pre-B-II cell A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. go-plus.json small pre-BII cell http://purl.obolibrary.org/obo/CL_0000954 CL:0000955 biolink:Cell pre-B-II cell A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain. go-plus.json pre-B-lymphocyte|pre-BII cell http://purl.obolibrary.org/obo/CL_0000955 CL:0000956 biolink:Cell pre-B-I cell A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. go-plus.json pre-BI cell|pro-B cell (Philadelphia nomenclature) http://purl.obolibrary.org/obo/CL_0000956 CL:0000957 biolink:Cell large pre-B-II cell A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. go-plus.json large pre-B cell|large pre-BII cell http://purl.obolibrary.org/obo/CL_0000957 CL:0000958 biolink:Cell T1 B cell A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. go-plus.json T1 B lymphocyte|transitional stage 1 B cell|T1 B-cell|T1 B-lymphocyte http://purl.obolibrary.org/obo/CL_0000958 CL:0000959 biolink:Cell T2 B cell A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. go-plus.json T2 B-lymphocyte|T2 B lymphocyte|transitional stage 2 B cell|T2 B-cell http://purl.obolibrary.org/obo/CL_0000959 CHEBI:17639 biolink:ChemicalSubstance 3-oxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17639 CHEBI:17637 biolink:ChemicalSubstance 6-methylsalicylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17637 CHEBI:17636 biolink:ChemicalSubstance sphingomyelin d18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_17636 chebi_ph7_3 CHEBI:17633 biolink:ChemicalSubstance guanosine 3',5'-bis(diphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17633 CL:0000950 biolink:Cell IgE plasmablast A plasmablast that secretes IgE. go-plus.json http://purl.obolibrary.org/obo/CL_0000950 CL:0000951 biolink:Cell IgE short lived plasma cell A short lived plasma cell that secretes IgE. go-plus.json http://purl.obolibrary.org/obo/CL_0000951 CHEBI:17634 biolink:ChemicalSubstance D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17634 CHEBI:17631 biolink:ChemicalSubstance alpha-D-Manp-(1->3)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-D-Manp go-plus.json http://purl.obolibrary.org/obo/CHEBI_17631 chebi_ph7_3 CHEBI:17632 biolink:ChemicalSubstance nitrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17632 chebi_ph7_3 CHEBI:17630 biolink:ChemicalSubstance kanamycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_17630 GO:0005615 biolink:CellularComponent extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. NIF_Subcellular:sao1425028079 go-plus.json intercellular space http://purl.obolibrary.org/obo/GO_0005615 goslim_drosophila|goslim_generic|goslim_chembl GO:0005616 biolink:CellularComponent larval serum protein complex A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0005616 GO:0005613 biolink:CellularComponent obsolete laminin receptor protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json laminin receptor protein http://purl.obolibrary.org/obo/GO_0005613 GO:0005614 biolink:CellularComponent interstitial matrix A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens. go-plus.json http://purl.obolibrary.org/obo/GO_0005614 GO:0005611 biolink:CellularComponent laminin-6 complex A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains. go-plus.json laminin-311 complex|laminin-6A complex http://purl.obolibrary.org/obo/GO_0005611 GO:0005612 biolink:CellularComponent laminin-7 complex A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains. go-plus.json laminin-7A|laminin-321 complex http://purl.obolibrary.org/obo/GO_0005612 GO:0005610 biolink:CellularComponent laminin-5 complex A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains. go-plus.json laminin-3A32 complex|laminin-5A complex|laminin-332 complex http://purl.obolibrary.org/obo/GO_0005610 GO:0005619 biolink:CellularComponent ascospore wall The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi. go-plus.json fungal-type spore wall http://purl.obolibrary.org/obo/GO_0005619 GO:0005617 biolink:CellularComponent obsolete larval serum protein-1 OBSOLETE. (Was not defined before being made obsolete). go-plus.json LSP1|larval serum protein-1 http://purl.obolibrary.org/obo/GO_0005617 GO:0005618 biolink:CellularComponent cell wall The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins. Wikipedia:Cell_wall go-plus.json http://purl.obolibrary.org/obo/GO_0005618 goslim_chembl|goslim_candida|goslim_yeast|gocheck_do_not_annotate|goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic GO:0005626 biolink:CellularComponent obsolete insoluble fraction OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water. go-plus.json particle-bound|insoluble fraction http://purl.obolibrary.org/obo/GO_0005626 GO:0005627 biolink:CellularComponent obsolete ascus OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number). go-plus.json ascus http://purl.obolibrary.org/obo/GO_0005627 GO:0005624 biolink:CellularComponent obsolete membrane fraction OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes. go-plus.json membrane fraction http://purl.obolibrary.org/obo/GO_0005624 GO:0005625 biolink:CellularComponent obsolete soluble fraction OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water. go-plus.json soluble fraction|soluble http://purl.obolibrary.org/obo/GO_0005625 GO:0005622 biolink:CellularComponent intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. Wikipedia:Intracellular go-plus.json protoplasm|protoplast|nucleocytoplasm|intracellular|internal to cell http://purl.obolibrary.org/obo/GO_0005622 goslim_generic|goslim_chembl|gocheck_do_not_annotate|goslim_plant|goslim_metagenomics PR:000018934 biolink:Protein aryl hydrocarbon receptor proteolytic cleavage product An aryl hydrocarbon receptor that has been processed by proteolytic cleavage. go-plus.json AHR/ClvPrd http://purl.obolibrary.org/obo/PR_000018934 GO:0005623 biolink:CellularComponent obsolete cell OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Wikipedia:Cell_(biology)|NIF_Subcellular:sao1813327414 go-plus.json http://purl.obolibrary.org/obo/GO_0005623 GO:0005620 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005620 GO:0005621 biolink:CellularComponent cellular bud scar Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age. go-plus.json http://purl.obolibrary.org/obo/GO_0005621 CHEBI:42589 biolink:ChemicalSubstance beta-L-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_42589 chebi_ph7_3 GO:0005628 biolink:CellularComponent prospore membrane The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe. go-plus.json FSM|ascospore-type prospore membrane|forespore membrane http://purl.obolibrary.org/obo/GO_0005628 GO:0005604 biolink:CellularComponent basement membrane A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. Wikipedia:Basement_membrane go-plus.json basal lamina|lamina densa|basement lamina http://purl.obolibrary.org/obo/GO_0005604 GO:0005605 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005605 GO:0005602 biolink:CellularComponent complement component C1 complex A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains. go-plus.json complement component C1q complex http://purl.obolibrary.org/obo/GO_0005602 GO:0005603 biolink:CellularComponent obsolete complement component C2 complex OBSOLETE. (Was not defined before being made obsolete). go-plus.json complement component C2 complex http://purl.obolibrary.org/obo/GO_0005603 GO:0005600 biolink:CellularComponent collagen type XIII trimer A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0005600 GO:0005601 biolink:CellularComponent classical-complement-pathway C3/C5 convertase complex A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone. go-plus.json http://purl.obolibrary.org/obo/GO_0005601 CHEBI:42564 biolink:ChemicalSubstance alpha-D-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_42564 chebi_ph7_3 GO:0005608 biolink:CellularComponent laminin-3 complex A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains. go-plus.json laminin-121 complex http://purl.obolibrary.org/obo/GO_0005608 GO:0005609 biolink:CellularComponent laminin-4 complex A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains. go-plus.json laminin-221 complex http://purl.obolibrary.org/obo/GO_0005609 GO:0005606 biolink:CellularComponent laminin-1 complex A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains. go-plus.json laminin-111 complex http://purl.obolibrary.org/obo/GO_0005606 GO:0005607 biolink:CellularComponent laminin-2 complex A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains. go-plus.json laminin-211 complex http://purl.obolibrary.org/obo/GO_0005607 CHEBI:17590 biolink:ChemicalSubstance octane go-plus.json http://purl.obolibrary.org/obo/CHEBI_17590 chebi_ph7_3 CHEBI:17589 biolink:ChemicalSubstance 3-chloro-cis,cis-muconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17589 chebi_ph7_3 CHEBI:17587 biolink:ChemicalSubstance L-gulono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17587 chebi_ph7_3 CHEBI:17588 biolink:ChemicalSubstance L-homocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17588 CHEBI:17585 biolink:ChemicalSubstance trans-hexadec-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17585 chebi_ph7_3 CHEBI:17586 biolink:ChemicalSubstance CoA-glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17586 CHEBI:17583 biolink:ChemicalSubstance N-(long-chain-fatty-acyl)-L-glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17583 chebi_ph7_3 CHEBI:17581 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_17581 chebi_ph7_3 CHEBI:17582 biolink:ChemicalSubstance isochorismic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17582 CHEBI:17580 biolink:ChemicalSubstance linalool go-plus.json http://purl.obolibrary.org/obo/CHEBI_17580 chebi_ph7_3 CHEBI:42548 biolink:ChemicalSubstance alpha-L-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_42548 chebi_ph7_3 CHEBI:17578 biolink:ChemicalSubstance toluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17578 chebi_ph7_3 CHEBI:17579 biolink:ChemicalSubstance beta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17579 chebi_ph7_3 CHEBI:17576 biolink:ChemicalSubstance (3R)-3-hydroxy-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17576 CHEBI:17574 biolink:ChemicalSubstance biochanin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_17574 CHEBI:17575 biolink:ChemicalSubstance S-(5-deoxy-D-ribos-5-yl)-L-homocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17575 CHEBI:17572 biolink:ChemicalSubstance 5-amino-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17572 CHEBI:17573 biolink:ChemicalSubstance glycyrrhetinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17573 chebi_ph7_3 CHEBI:17571 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_17571 chebi_ph7_3 CHEBI:42539 biolink:ChemicalSubstance (R)-3-hydroxytetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42539 CHEBI:42534 biolink:ChemicalSubstance epitestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_42534 chebi_ph7_3 CHEBI:545687 biolink:ChemicalSubstance traumatic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_545687 RO:0012003 biolink:OntologyClass acts on population of p acts on population of c iff c' is a collection, has members of type c, and p has participant c RO:0012003 go-plus.json http://purl.obolibrary.org/obo/RO_0012003 NCBITaxon:197562 biolink:OrganismalEntity Pancrustacea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_197562 NCBITaxon:197563 biolink:OrganismalEntity Mandibulata go-plus.json mandibulates http://purl.obolibrary.org/obo/NCBITaxon_197563 RO:0012008 biolink:OntologyClass results in fusion of RO:0012008 go-plus.json http://purl.obolibrary.org/obo/RO_0012008 CHEBI:569624 biolink:ChemicalSubstance papulacandin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_569624 chebi_ph7_3 CHEBI:17598 biolink:ChemicalSubstance phorbol 12,13-dibutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17598 chebi_ph7_3 CHEBI:17596 biolink:ChemicalSubstance inosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17596 chebi_ph7_3 CHEBI:17597 biolink:ChemicalSubstance 4-hydroxybenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17597 chebi_ph7_3 CHEBI:17594 biolink:ChemicalSubstance hydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17594 chebi_ph7_3 CHEBI:17592 biolink:ChemicalSubstance N(5)-methyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17592 CHEBI:17593 biolink:ChemicalSubstance maltooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17593 GO:0030659 biolink:CellularComponent cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030659 GO:0030657 biolink:BiologicalProcess obsolete regulation of coenzyme and prosthetic group metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups. go-plus.json regulation of coenzyme and prosthetic group metabolic process http://purl.obolibrary.org/obo/GO_0030657 GO:0030658 biolink:CellularComponent transport vesicle membrane The lipid bilayer surrounding a transport vesicle. go-plus.json secretory vesicle membrane|constitutive secretory pathway transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030658 GO:0005699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005699 GO:0030655 biolink:BiologicalProcess beta-lactam antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. go-plus.json beta-lactam antibiotic degradation|beta-lactam antibiotic breakdown|beta-lactam antibiotic catabolism http://purl.obolibrary.org/obo/GO_0030655 GO:0030656 biolink:BiologicalProcess regulation of vitamin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json regulation of vitamin metabolism http://purl.obolibrary.org/obo/GO_0030656 GO:0005697 biolink:CellularComponent telomerase holoenzyme complex Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0005697 goslim_pir GO:0030653 biolink:BiologicalProcess beta-lactam antibiotic metabolic process The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. go-plus.json beta-lactam antibiotic metabolism http://purl.obolibrary.org/obo/GO_0030653 GO:0005698 biolink:CellularComponent obsolete centromere OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid. go-plus.json centromere http://purl.obolibrary.org/obo/GO_0005698 GO:0030654 biolink:BiologicalProcess beta-lactam antibiotic biosynthetic process The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. go-plus.json beta-lactam antibiotic synthesis|beta-lactam antibiotic formation|beta-lactam antibiotic biosynthesis|beta-lactam antibiotic anabolism http://purl.obolibrary.org/obo/GO_0030654 GO:0005695 biolink:CellularComponent obsolete chromatid OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis. go-plus.json chromatid http://purl.obolibrary.org/obo/GO_0005695 GO:0005696 biolink:CellularComponent obsolete telomere OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA. go-plus.json telomere http://purl.obolibrary.org/obo/GO_0005696 GO:0005693 biolink:CellularComponent U12 snRNP A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json snRNP U12 http://purl.obolibrary.org/obo/GO_0005693 GO:0005694 biolink:CellularComponent chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. Wikipedia:Chromosome go-plus.json interphase chromosome|chromatid|prophase chromosome http://purl.obolibrary.org/obo/GO_0005694 goslim_metagenomics|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_candida|goslim_agr|goslim_yeast|goslim_pir|goslim_drosophila|goslim_aspergillus GO:0005691 biolink:CellularComponent U6atac snRNP A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of spliceosomal complexes. go-plus.json snRNP U6atac http://purl.obolibrary.org/obo/GO_0005691 GO:0005692 biolink:CellularComponent U11 snRNP A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json snRNP U11|12S U11 snRNP http://purl.obolibrary.org/obo/GO_0005692 GO:0005690 biolink:CellularComponent U4atac snRNP A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes. go-plus.json snRNP U4atac http://purl.obolibrary.org/obo/GO_0005690 GO:0015018 biolink:MolecularActivity galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein. Reactome:R-HSA-1889955|Reactome:R-HSA-3560802|MetaCyc:2.4.1.135-RXN|RHEA:24168|EC:2.4.1.135|Reactome:R-HSA-9638064 go-plus.json glucuronosyltransferase I activity|uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity|UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity|UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0015018 GO:0015019 biolink:MolecularActivity heparan-alpha-glucosaminide N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide. EC:2.3.1.78|Reactome:R-HSA-1678660|RHEA:15125|MetaCyc:2.3.1.78-RXN|Reactome:R-HSA-2263492|Reactome:R-HSA-2090085|Reactome:R-HSA-9036056 go-plus.json heparin-alpha-glucosaminide N-acetyltransferase activity|acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity|acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0015019 GO:0015014 biolink:BiologicalProcess heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan. go-plus.json heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism|heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis|heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|heparan sulfate proteoglycan chain elongation|heparan sulfate proteoglycan formation, polysaccharide chain formation|heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process http://purl.obolibrary.org/obo/GO_0015014 GO:0015015 biolink:BiologicalProcess heparan sulfate proteoglycan biosynthetic process, enzymatic modification The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization. go-plus.json heparan sulfate proteoglycan formation, enzymatic modification|heparin proteoglycan biosynthetic process, enzymatic modification|heparan sulphate proteoglycan biosynthesis, enzymatic modification|heparan sulfate proteoglycan anabolism, enzymatic modification|heparan sulphate proteoglycan biosynthetic process, enzymatic modification|heparan sulfate proteoglycan synthesis, enzymatic modification http://purl.obolibrary.org/obo/GO_0015015 GO:0015016 biolink:MolecularActivity [heparan sulfate]-glucosamine N-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine. EC:2.8.2.8|RHEA:21980|Reactome:R-HSA-2022860|MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN go-plus.json PAPS:N-desulfoheparin sulfotransferase activity|glucosaminyl N-deacetylase/N-sulfotransferase activity|heparin-glucosamine N-sulfotransferase activity|desulfoheparin sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity|N-desulfoheparin sulfotransferase activity|heparitin N-sulfotransferase activity|heparitin sulfotransferase activity|3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity|PAPS:DSH sulfotransferase activity|3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity|heparan sulfate 2-N-sulfotransferase activity|heparin N-deacetylase/N-sulphotransferase activity|heparin N-sulfotransferase activity|N-HSST activity|heparan sulfate N-deacetylase/N-sulfotransferase activity|heparan sulfate N-sulfotransferase activity|N-heparan sulfate sulfotransferase activity|[heparan sulphate]-glucosamine N-sulphotransferase activity|heparitin N-sulphotransferase activity|heparin N-deacetylase/N-sulfotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0015016 GO:0015017 biolink:MolecularActivity obsolete glypican OBSOLETE. (Was not defined before being made obsolete). go-plus.json glypican http://purl.obolibrary.org/obo/GO_0015017 GO:0030651 biolink:BiologicalProcess peptide antibiotic biosynthetic process The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity. go-plus.json peptide antibiotic synthesis|peptide antibiotic formation|peptide antibiotic biosynthesis|peptide antibiotic anabolism http://purl.obolibrary.org/obo/GO_0030651 GO:0015010 biolink:BiologicalProcess tetrahydrocorphin metabolic process The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins. go-plus.json tetrahydrocorphin metabolism http://purl.obolibrary.org/obo/GO_0015010 GO:0015011 biolink:BiologicalProcess nickel-tetrapyrrole coenzyme metabolic process The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase. go-plus.json nickel-tetrapyrrole coenzyme metabolism|coenzyme F430 metabolic process http://purl.obolibrary.org/obo/GO_0015011 GO:0030652 biolink:BiologicalProcess peptide antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity. go-plus.json peptide antibiotic degradation|peptide antibiotic catabolism|peptide antibiotic breakdown http://purl.obolibrary.org/obo/GO_0030652 CHEBI:134140 biolink:ChemicalSubstance 2-acylglycerol 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134140 chebi_ph7_3 GO:0015012 biolink:BiologicalProcess heparan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. RESID:AA0210 go-plus.json heparan sulfate proteoglycan biosynthesis|heparin proteoglycan biosynthetic process|heparan sulfate proteoglycan anabolism|heparan sulphate proteoglycan biosynthetic process|heparan sulphate proteoglycan biosynthesis|heparan sulfate proteoglycan synthesis|heparan sulfate proteoglycan formation http://purl.obolibrary.org/obo/GO_0015012 GO:0015013 biolink:BiologicalProcess heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan. go-plus.json heparin proteoglycan biosynthetic process, linkage to polypeptide|heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide|heparan sulfate proteoglycan anabolism, linkage to polypeptide|heparan sulphate proteoglycan biosynthesis, linkage to polypeptide|heparan sulfate proteoglycan synthesis, linkage to polypeptide|heparan sulfate proteoglycan formation, linkage to polypeptide http://purl.obolibrary.org/obo/GO_0015013 GO:0030650 biolink:BiologicalProcess peptide antibiotic metabolic process The chemical reactions and pathways involving peptides with antibiotic activity. go-plus.json peptide antibiotic metabolism http://purl.obolibrary.org/obo/GO_0030650 CHEBI:134144 biolink:ChemicalSubstance 2-acylglycerol 20:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134144 chebi_ph7_3 CHEBI:134141 biolink:ChemicalSubstance 2-acylglycerol 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134141 chebi_ph7_3 CHEBI:134142 biolink:ChemicalSubstance 2-acylglycerol 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134142 chebi_ph7_3 GO:0030648 biolink:BiologicalProcess aminoglycoside antibiotic biosynthetic process The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. go-plus.json aminoglycoside antibiotic formation|aminoglycoside antibiotic biosynthesis|aminoglycoside antibiotic anabolism|aminoglycoside antibiotic synthesis http://purl.obolibrary.org/obo/GO_0030648 GO:0030649 biolink:BiologicalProcess aminoglycoside antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. go-plus.json aminoglycoside antibiotic catabolism|aminoglycoside antibiotic degradation|aminoglycoside antibiotic breakdown http://purl.obolibrary.org/obo/GO_0030649 GO:0030646 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030646 GO:0030647 biolink:BiologicalProcess aminoglycoside antibiotic metabolic process The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. go-plus.json aminoglycoside antibiotic metabolism http://purl.obolibrary.org/obo/GO_0030647 GO:0030644 biolink:BiologicalProcess cellular chloride ion homeostasis Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030644 GO:0030645 biolink:BiologicalProcess glucose catabolic process to butyrate The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum. go-plus.json glucose fermentation to butyrate|butyrate fermentation http://purl.obolibrary.org/obo/GO_0030645 GO:0030642 biolink:BiologicalProcess cellular sulfate ion homeostasis Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell. go-plus.json sulphate ion homeostasis http://purl.obolibrary.org/obo/GO_0030642 GO:0030643 biolink:BiologicalProcess cellular phosphate ion homeostasis Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030643 GO:0015029 biolink:MolecularActivity obsolete internalization receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json internalization receptor activity http://purl.obolibrary.org/obo/GO_0015029 CHEBI:134158 biolink:ChemicalSubstance N-acylethanolamine 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134158 chebi_ph7_3 CHEBI:134159 biolink:ChemicalSubstance N-acylethanolamine 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134159 chebi_ph7_3 CHEBI:134156 biolink:ChemicalSubstance N-acylethanolamine 16:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134156 chebi_ph7_3 CHEBI:134157 biolink:ChemicalSubstance N-acylethanolamine 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134157 chebi_ph7_3 GO:0015025 biolink:MolecularActivity obsolete GPI-anchored membrane-bound receptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json GPI-anchored membrane-bound receptor http://purl.obolibrary.org/obo/GO_0015025 GO:0015026 biolink:MolecularActivity coreceptor activity Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity. go-plus.json coreceptor, soluble ligand activity|coreceptor, insoluble ligand activity http://purl.obolibrary.org/obo/GO_0015026 GO:0015027 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015027 GO:0015028 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015028 GO:0030640 biolink:BiologicalProcess polyketide catabolic process The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. go-plus.json polyketide breakdown|polyketide catabolism|polyketide degradation http://purl.obolibrary.org/obo/GO_0030640 GO:0015021 biolink:MolecularActivity heparin-sulfate lyase activity Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar. MetaCyc:4.2.2.8-RXN|EC:4.2.2.8 go-plus.json heparin-sulfate eliminase activity|heparin-sulphate lyase activity|heparitin-sulfate lyase activity|heparitinase I|[heparan sulfate]-sulfate lyase activity|heparitinase II http://purl.obolibrary.org/obo/GO_0015021 CHEBI:134150 biolink:ChemicalSubstance N-acylglycine 16:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134150 GO:0030641 biolink:BiologicalProcess regulation of cellular pH Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment. go-plus.json cellular hydrogen ion homeostasis|proton homeostasis http://purl.obolibrary.org/obo/GO_0030641 GO:0015022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015022 CHEBI:134151 biolink:ChemicalSubstance N-acylglycine 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134151 GO:0015023 biolink:MolecularActivity obsolete syndecan OBSOLETE. (Was not defined before being made obsolete). go-plus.json syndecan http://purl.obolibrary.org/obo/GO_0015023 GO:0015024 biolink:MolecularActivity glucuronate-2-sulfatase activity Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. EC:3.1.6.18|MetaCyc:3.1.6.18-RXN go-plus.json chondro-2-sulfatase activity|polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity|glucurono-2-sulfatase activity|glucuronate-2-sulphatase activity http://purl.obolibrary.org/obo/GO_0015024 CHEBI:134152 biolink:ChemicalSubstance N-acylglycine 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134152 GO:0015020 biolink:MolecularActivity glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. Reactome:R-HSA-159194|MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN|Reactome:R-HSA-9632039|Reactome:R-HSA-9036102|Reactome:R-HSA-9036104|Reactome:R-HSA-5617143|Reactome:R-HSA-8941701|EC:2.4.1.17|Reactome:R-HSA-9638097|Reactome:R-HSA-2162099|Reactome:R-HSA-9632038|Reactome:R-HSA-174931|Reactome:R-HSA-174916|Reactome:R-HSA-5604975|Reactome:R-HSA-5604954|Reactome:R-HSA-159179|RHEA:21032 go-plus.json UDP-glucuronate-bilirubin glucuronyltransferase activity|UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|UDP glucuronyltransferase activity|p-nitrophenol UDP-glucuronyltransferase activity|uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|3-OH androgenic UDPGT activity|uridine diphosphate glucuronyltransferase activity|ciramadol UDP-glucuronyltransferase activity|uridine diphosphoglucuronyltransferase activity|pnp-UDPGT activity|UDP glucuronate-estriol glucuronosyltransferase activity|uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|p-phenylphenol glucuronyltransferase activity|4-nitrophenol UDP-glucuronyltransferase activity|p-nitrophenylglucuronosyltransferase activity|p-hydroxybiphenyl UDP glucuronyltransferase activity|bilirubin UDP-glucuronosyltransferase activity|17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|GT activity|17beta-hydroxysteroid UDP-glucuronosyltransferase activity|UDPGT activity|uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|uridine 5'-diphosphoglucuronyltransferase activity|phenyl-UDP-glucuronosyltransferase activity|morphine glucuronyltransferase activity|1-naphthol glucuronyltransferase activity|UDPGA-glucuronyltransferase activity|UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|bilirubin monoglucuronide glucuronyltransferase activity|4-methylumbelliferone UDP-glucuronosyltransferase activity|UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|UDP-glucuronosyltransferase activity|uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|1-naphthol-UDP-glucuronosyltransferase activity|3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|UDP glucuronate-estradiol-glucuronosyltransferase activity|UDP-glucuronyltransferase activity|bilirubin glucuronyltransferase activity|PNP-UDPGT|estriol UDPglucuronosyltransferase activity|UDP glucuronic acid transferase activity|estrone UDPglucuronosyltransferase activity|bilirubin uridine diphosphoglucuronyltransferase activity|4-nitrophenol UDPGT activity|4-hydroxybiphenyl UDP-glucuronosyltransferase activity|3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|17-OH steroid UDPGT activity|p-nitrophenol UDP-glucuronosyltransferase activity|uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|UDPGA transferase activity|UDP glucuronosyltransferase activity|bilirubin UDPGT activity|uridine diphosphoglucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0015020 GO:0030637 biolink:BiologicalProcess obsolete acetate derivative catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of derivatives of acetic acid. go-plus.json acetate derivative degradation|acetate derivative catabolism|acetate derivative breakdown|acetate derivative catabolic process http://purl.obolibrary.org/obo/GO_0030637 GO:0030638 biolink:BiologicalProcess polyketide metabolic process The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. go-plus.json polyketide metabolism http://purl.obolibrary.org/obo/GO_0030638 GO:0030635 biolink:BiologicalProcess obsolete acetate derivative metabolic process OBSOLETE. The chemical reactions and pathways involving derivatives of acetic acid. go-plus.json acetate derivative metabolic process|acetate derivative metabolism http://purl.obolibrary.org/obo/GO_0030635 GO:0005679 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005679 GO:0030636 biolink:BiologicalProcess obsolete acetate derivative biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of derivatives of acetic acid. go-plus.json acetate derivative biosynthetic process|acetate derivative biosynthesis|acetate derivative anabolism|acetate derivative synthesis|acetate derivative formation http://purl.obolibrary.org/obo/GO_0030636 GO:0030633 biolink:BiologicalProcess D-alanine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids. go-plus.json D-alanine family amino acid degradation|D-alanine family amino acid breakdown|D-alanine family amino acid catabolism http://purl.obolibrary.org/obo/GO_0030633 GO:0005677 biolink:CellularComponent chromatin silencing complex Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing. go-plus.json http://purl.obolibrary.org/obo/GO_0005677 GO:0005678 biolink:CellularComponent obsolete chromatin assembly complex OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure. go-plus.json chromatin assembly complex|nucleosome assembly complex http://purl.obolibrary.org/obo/GO_0005678 GO:0030634 biolink:BiologicalProcess carbon fixation by acetyl-CoA pathway A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2). MetaCyc:CODH-PWY|Wikipedia:Wood-Ljungdahl_pathway go-plus.json acetyl CoA pathway|reductive acetyl CoA pathway|Ljungdahl-Wood pathway http://purl.obolibrary.org/obo/GO_0030634 GO:0005675 biolink:CellularComponent transcription factor TFIIH holo complex A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex. go-plus.json holo TFIIH complex http://purl.obolibrary.org/obo/GO_0005675 GO:0030631 biolink:BiologicalProcess pyrrolysine incorporation The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases. RESID:AA0321 go-plus.json monomethylamine methyltransferase cofactor lysine adduct incorporation|lysine methylamine methyltransferase cofactor adduct incorporation http://purl.obolibrary.org/obo/GO_0030631 GO:0030632 biolink:BiologicalProcess D-alanine biosynthetic process The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid. go-plus.json D-alanine formation|D-alanine biosynthesis|D-alanine anabolism|D-alanine synthesis http://purl.obolibrary.org/obo/GO_0030632 GO:0005676 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005676 GO:0005673 biolink:CellularComponent transcription factor TFIIE complex A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH. go-plus.json http://purl.obolibrary.org/obo/GO_0005673 GO:0005674 biolink:CellularComponent transcription factor TFIIF complex A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0005674 GO:0005671 biolink:CellularComponent obsolete Ada2/Gcn5/Ada3 transcription activator complex OBSOLETE. A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues. go-plus.json ATAC complex http://purl.obolibrary.org/obo/GO_0005671 GO:0005672 biolink:CellularComponent transcription factor TFIIA complex A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12). go-plus.json http://purl.obolibrary.org/obo/GO_0005672 GO:0005670 biolink:CellularComponent obsolete transcription-activating factor, 30kD OBSOLETE. (Was not defined before being made obsolete). go-plus.json transcription-activating factor, 30kD http://purl.obolibrary.org/obo/GO_0005670 GO:0030639 biolink:BiologicalProcess polyketide biosynthetic process The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. go-plus.json polyketide anabolism|polyketide synthesis|polyketide biosynthesis|polyketide formation http://purl.obolibrary.org/obo/GO_0030639 CHEBI:134125 biolink:ChemicalSubstance (R)-NADHX go-plus.json http://purl.obolibrary.org/obo/CHEBI_134125 CHEBI:134129 biolink:ChemicalSubstance 1-acylglycerol 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134129 chebi_ph7_3 CHEBI:134127 biolink:ChemicalSubstance 1-acylglycerol 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134127 chebi_ph7_3 GO:0030630 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030630 CHEBI:134121 biolink:ChemicalSubstance N-oleoyl-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134121 chebi_ph7_3 CHEBI:134122 biolink:ChemicalSubstance N-oleoyl-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134122 chebi_ph7_3 GO:0030626 biolink:MolecularActivity U12 snRNA binding Binding to a U12 small nuclear RNA (U12 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030626 GO:0030627 biolink:MolecularActivity pre-mRNA 5'-splice site binding Binding to a pre-mRNA 5' splice site sequence. go-plus.json pre-mRNA 5' splice site binding http://purl.obolibrary.org/obo/GO_0030627 GO:0030624 biolink:MolecularActivity U6atac snRNA binding Binding to a U6atac small nuclear RNA (U6atac snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030624 GO:0030625 biolink:MolecularActivity U11 snRNA binding Binding to a U11 small nuclear RNA (U11 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030625 GO:0030622 biolink:MolecularActivity U4atac snRNA binding Binding to a U4atac small nuclear RNA (U4atac snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030622 GO:0005688 biolink:CellularComponent U6 snRNP A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes. go-plus.json snRNP U6 http://purl.obolibrary.org/obo/GO_0005688 GO:0005689 biolink:CellularComponent U12-type spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site. Wikipedia:Minor_spliceosome go-plus.json minor spliceosomal complex|AT-AC spliceosomal complex|minor (U12-type) spliceosomal complex http://purl.obolibrary.org/obo/GO_0005689 GO:0030623 biolink:MolecularActivity U5 snRNA binding Binding to a U5 small nuclear RNA (U5 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030623 GO:0005686 biolink:CellularComponent U2 snRNP A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json 17S U2 snRNP|snRNP U2 http://purl.obolibrary.org/obo/GO_0005686 GO:0030620 biolink:MolecularActivity U2 snRNA binding Binding to a U2 small nuclear RNA (U2 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030620 GO:0005687 biolink:CellularComponent U4 snRNP A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes. go-plus.json snRNP U4 http://purl.obolibrary.org/obo/GO_0005687 GO:0030621 biolink:MolecularActivity U4 snRNA binding Binding to a U4 small nuclear RNA (U4 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030621 GO:0005684 biolink:CellularComponent U2-type spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. go-plus.json major spliceosomal complex|major (U2-type) spliceosomal complex|GT-AG spliceosome http://purl.obolibrary.org/obo/GO_0005684 GO:0005685 biolink:CellularComponent U1 snRNP A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json snRNP U1 http://purl.obolibrary.org/obo/GO_0005685 GO:0005682 biolink:CellularComponent U5 snRNP A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes. go-plus.json snRNP U5 http://purl.obolibrary.org/obo/GO_0005682 GO:0005683 biolink:CellularComponent U7 snRNP A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs. go-plus.json snRNP U7 http://purl.obolibrary.org/obo/GO_0005683 GO:0005680 biolink:CellularComponent anaphase-promoting complex A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. Wikipedia:Anaphase-promoting_complex go-plus.json APC|cyclosome|anaphase promoting complex http://purl.obolibrary.org/obo/GO_0005680 GO:0005681 biolink:CellularComponent spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. Wikipedia:Spliceosome go-plus.json spliceosome|spliceosome complex http://purl.obolibrary.org/obo/GO_0005681 goslim_pir GO:0030628 biolink:MolecularActivity pre-mRNA 3'-splice site binding Binding to a pre-mRNA 3' splice site sequence. go-plus.json pre-mRNA 3' splice site binding http://purl.obolibrary.org/obo/GO_0030628 GO:0030629 biolink:MolecularActivity U6 snRNA 3'-end binding Binding to a U6 small nuclear RNA (U6 snRNA) at the 3' end. go-plus.json U6 snRNA 3' end binding http://purl.obolibrary.org/obo/GO_0030629 GO:0015007 biolink:MolecularActivity obsolete electron carrier, chlorophyll electron transport system OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system. go-plus.json chlorophyll electron carrier|electron carrier, chlorophyll electron transport system http://purl.obolibrary.org/obo/GO_0015007 GO:0015008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015008 GO:0015009 biolink:BiologicalProcess corrin metabolic process The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule. go-plus.json corrin metabolism http://purl.obolibrary.org/obo/GO_0015009 GO:0015003 biolink:MolecularActivity obsolete copper electron carrier OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system. go-plus.json copper electron carrier http://purl.obolibrary.org/obo/GO_0015003 GO:0015004 biolink:MolecularActivity obsolete small blue copper electron carrier OBSOLETE. (Was not defined before being made obsolete). go-plus.json small blue copper electron carrier http://purl.obolibrary.org/obo/GO_0015004 GO:0015005 biolink:MolecularActivity obsolete azurin OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin. go-plus.json azurin http://purl.obolibrary.org/obo/GO_0015005 CHEBI:134138 biolink:ChemicalSubstance 2-acylglycerol 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134138 chebi_ph7_3 GO:0015006 biolink:MolecularActivity obsolete plastocyanin OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I. go-plus.json plastocyanin http://purl.obolibrary.org/obo/GO_0015006 GO:0015000 biolink:MolecularActivity obsolete polyferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json polyferredoxin http://purl.obolibrary.org/obo/GO_0015000 GO:0015001 biolink:MolecularActivity obsolete high-potential iron-sulfur carrier OBSOLETE. (Was not defined before being made obsolete). go-plus.json high-potential iron-sulphur carrier|HiPIP|high-potential iron-sulfur carrier http://purl.obolibrary.org/obo/GO_0015001 GO:0015002 biolink:MolecularActivity obsolete heme-copper terminal oxidase activity OBSOLETE. Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane. go-plus.json haem-copper terminal oxidase activity http://purl.obolibrary.org/obo/GO_0015002 CHEBI:134133 biolink:ChemicalSubstance 1-acylglycerol 20:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134133 chebi_ph7_3 CHEBI:134130 biolink:ChemicalSubstance 1-acylglycerol 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134130 chebi_ph7_3 CHEBI:134131 biolink:ChemicalSubstance 1-acylglycerol 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134131 chebi_ph7_3 GO:0005659 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005659 GO:0030615 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030615 GO:0030616 biolink:MolecularActivity obsolete transforming growth factor beta receptor, common-partner cytoplasmic mediator activity OBSOLETE. A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription. go-plus.json TGFbeta receptor, common-partner cytoplasmic mediator activity|common-partner SMAD protein|co-SMAD protein|TGF-beta receptor, common-partner cytoplasmic mediator activity|common mediator SMAD protein|common partner SMAD protein|common-mediator SMAD protein http://purl.obolibrary.org/obo/GO_0030616 GO:0030613 biolink:MolecularActivity oxidoreductase activity, acting on phosphorus or arsenic in donors Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.20.-.- go-plus.json oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors http://purl.obolibrary.org/obo/GO_0030613 GO:0005657 biolink:CellularComponent replication fork The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. Wikipedia:Replication_fork go-plus.json replication focus http://purl.obolibrary.org/obo/GO_0005657 GO:0030614 biolink:MolecularActivity oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide. EC:1.20.4.- go-plus.json oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor http://purl.obolibrary.org/obo/GO_0030614 GO:0005658 biolink:CellularComponent alpha DNA polymerase:primase complex A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis. go-plus.json pol-prim|heterotetrameric polymerase alpha holoenzyme|primosome|DNA polymerase alpha:primase complex http://purl.obolibrary.org/obo/GO_0005658 GO:0005655 biolink:CellularComponent nucleolar ribonuclease P complex A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules. go-plus.json nucleolar RNase P complex http://purl.obolibrary.org/obo/GO_0005655 GO:0030611 biolink:MolecularActivity arsenate reductase activity Catalysis of the interconversion of arsenate and arsenite. go-plus.json http://purl.obolibrary.org/obo/GO_0030611 GO:0005656 biolink:CellularComponent nuclear pre-replicative complex A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins. go-plus.json pre-replicative complex|eukaryotic pre-replicative complex|pre-RC http://purl.obolibrary.org/obo/GO_0005656 PR:000018902 biolink:Protein pituitary adenylate cyclase-activating polypeptide proteolytic cleavage product A pituitary adenylate cyclase-activating polypeptide that has been processed by proteolytic cleavage. go-plus.json ADCYAP1/ClvPrd http://purl.obolibrary.org/obo/PR_000018902 GO:0030612 biolink:MolecularActivity arsenate reductase (thioredoxin) activity Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin. MetaCyc:RXN-10737 go-plus.json http://purl.obolibrary.org/obo/GO_0030612 GO:0005653 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005653 GO:0005654 biolink:CellularComponent nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus. Wikipedia:Nucleoplasm|NIF_Subcellular:sao661522542 go-plus.json http://purl.obolibrary.org/obo/GO_0005654 goslim_plant|goslim_generic|goslim_chembl GO:0030610 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030610 GO:0005651 biolink:CellularComponent obsolete exportin OBSOLETE. (Was not defined before being made obsolete). go-plus.json exportin http://purl.obolibrary.org/obo/GO_0005651 GO:0005652 biolink:CellularComponent nuclear lamina The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane. Wikipedia:Nuclear_lamina|NIF_Subcellular:sao1455996588 go-plus.json http://purl.obolibrary.org/obo/GO_0005652 GO:0005650 biolink:CellularComponent obsolete importin, alpha-subunit transport factor OBSOLETE. (Was not defined before being made obsolete). go-plus.json CAS|importin, alpha-subunit transport factor http://purl.obolibrary.org/obo/GO_0005650 GO:0030619 biolink:MolecularActivity U1 snRNA binding Binding to a U1 small nuclear RNA (U1 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0030619 GO:0030617 biolink:MolecularActivity obsolete transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity OBSOLETE. A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators. go-plus.json inhibitory SMAD protein|TGFbeta receptor, inhibitory cytoplasmic mediator activity|TGF-beta receptor, inhibitory cytoplasmic mediator activity http://purl.obolibrary.org/obo/GO_0030617 GO:0030618 biolink:MolecularActivity obsolete transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity OBSOLETE. A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription. go-plus.json pathway-restricted SMAD protein|receptor-regulated SMAD protein|TGFbeta receptor, pathway-specific cytoplasmic mediator activity|pathway-specific SMAD protein|pathway restricted SMAD protein|TGF-beta receptor, pathway-specific cytoplasmic mediator activity|receptor regulated SMAD protein http://purl.obolibrary.org/obo/GO_0030618 CHEBI:134103 biolink:ChemicalSubstance N-arachidonoyl-L-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134103 chebi_ph7_3 CHEBI:134102 biolink:ChemicalSubstance (R)-2-amino-4-oxopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134102 chebi_ph7_3 GO:0030604 biolink:MolecularActivity 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH. EC:1.1.1.267|RHEA:13717|KEGG_REACTION:R05688|MetaCyc:DXPREDISOM-RXN go-plus.json DXP-reductoisomerase activity|1-deoxyxylulose-5-phosphate reductoisomerase activity|2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)|1-deoxy-D-xylulose-5-phosphate isomeroreductase activity|DOXP reductoisomerase activity|2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity http://purl.obolibrary.org/obo/GO_0030604 GO:0030605 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030605 GO:0030602 biolink:MolecularActivity obsolete chymosin activity OBSOLETE. Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein. go-plus.json rennin (but this should be avoided since it leads to confusion with renin)|chymosin activity|rennin http://purl.obolibrary.org/obo/GO_0030602 GO:0005668 biolink:CellularComponent RNA polymerase transcription factor SL1 complex A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48. go-plus.json TIF-IB|selectivity factor SL1 complex http://purl.obolibrary.org/obo/GO_0005668 GO:0005669 biolink:CellularComponent transcription factor TFIID complex A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0005669 GO:0030603 biolink:MolecularActivity oxaloacetase activity Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate. EC:3.7.1.1|MetaCyc:OXALOACETASE-RXN|KEGG_REACTION:R00338|RHEA:24432 go-plus.json oxalacetic hydrolase activity|oxaloacetate acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0030603 GO:0030600 biolink:MolecularActivity feruloyl esterase activity Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide. MetaCyc:3.1.1.73-RXN|EC:3.1.1.73 go-plus.json FAE-I|FAE-III|FAE-II|FAEA|cinnamoyl ester hydrolase activity|4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity|hemicellulase accessory|hydroxycinnamoyl esterase activity|cinnAE|ferulic acid esterase activity http://purl.obolibrary.org/obo/GO_0030600 GO:0005666 biolink:CellularComponent RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. go-plus.json DNA-directed RNA polymerase III activity|DNA-directed RNA polymerase III complex http://purl.obolibrary.org/obo/GO_0005666 GO:0005667 biolink:CellularComponent transcription regulator complex A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. go-plus.json transcription factor complex|nuclear transcription factor complex|cytoplasmic transcription factor complex http://purl.obolibrary.org/obo/GO_0005667 goslim_pir GO:0030601 biolink:MolecularActivity obsolete aminopeptidase B activity OBSOLETE. Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys. go-plus.json cytosol aminopeptidase IV|Cl--activated arginine aminopeptidase activity|arginyl aminopeptidase activity|arylamidase II|aminopeptidase B activity|L-arginine aminopeptidase activity http://purl.obolibrary.org/obo/GO_0030601 GO:0005664 biolink:CellularComponent nuclear origin of replication recognition complex A multisubunit complex that is located at the replication origins of a chromosome in the nucleus. go-plus.json eukaryotic ORC|nuclear ORC http://purl.obolibrary.org/obo/GO_0005664 GO:0005665 biolink:CellularComponent RNA polymerase II, core complex RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. go-plus.json RNA polymerase II complex|DNA-directed RNA polymerase II, core complex|RNAP II complex http://purl.obolibrary.org/obo/GO_0005665 GO:0005662 biolink:CellularComponent DNA replication factor A complex A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa. Wikipedia:Replication_protein_A go-plus.json replication protein A|RPA http://purl.obolibrary.org/obo/GO_0005662 GO:0005663 biolink:CellularComponent DNA replication factor C complex A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides. go-plus.json activator 1 complex|RFC complex http://purl.obolibrary.org/obo/GO_0005663 goslim_pir GO:0005660 biolink:CellularComponent obsolete delta-DNA polymerase cofactor complex OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP. go-plus.json delta DNA polymerase cofactor complex|delta-DNA polymerase cofactor complex http://purl.obolibrary.org/obo/GO_0005660 GO:0005661 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005661 GO:0030608 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030608 GO:0030609 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030609 GO:0030606 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030606 GO:0030607 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030607 CHEBI:6746 biolink:ChemicalSubstance menadiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_6746 chebi_ph7_3 CHEBI:134119 biolink:ChemicalSubstance beta-muricholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134119 chebi_ph7_3 CHEBI:134116 biolink:ChemicalSubstance alpha-muricholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134116 chebi_ph7_3 CHEBI:134110 biolink:ChemicalSubstance (9Z,11S,12Z,15Z)-11-hydroperoxyoctadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134110 chebi_ph7_3 GO:0005637 biolink:CellularComponent nuclear inner membrane The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope. NIF_Subcellular:sao1612527463 go-plus.json inner envelope|nucleus inner membrane|inner nuclear membrane http://purl.obolibrary.org/obo/GO_0005637 GO:0005638 biolink:CellularComponent lamin filament Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C. go-plus.json type V intermediate filament http://purl.obolibrary.org/obo/GO_0005638 GO:0005635 biolink:CellularComponent nuclear envelope The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). Wikipedia:Nuclear_envelope go-plus.json http://purl.obolibrary.org/obo/GO_0005635 goslim_plant|goslim_generic|goslim_chembl GO:0005636 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005636 GO:0005633 biolink:CellularComponent ascus lipid droplet Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins. go-plus.json ascus lipid particle http://purl.obolibrary.org/obo/GO_0005633 GO:0005634 biolink:CellularComponent nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. NIF_Subcellular:sao1702920020|Wikipedia:Cell_nucleus go-plus.json horsetail nucleus|cell nucleus http://purl.obolibrary.org/obo/GO_0005634 goslim_yeast|goslim_agr|goslim_candida|goslim_plant|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse GO:0005631 biolink:CellularComponent chitosan layer of spore wall The second outermost layer of the spore wall, as described in Saccharomyces. go-plus.json http://purl.obolibrary.org/obo/GO_0005631 GO:0005632 biolink:CellularComponent inner layer of spore wall Either of the two innermost layers of the spore wall, as described in Saccharomyces. go-plus.json http://purl.obolibrary.org/obo/GO_0005632 GO:0005630 biolink:CellularComponent dityrosine layer of spore wall The outermost layer of the spore wall, as described in Saccharomyces. go-plus.json http://purl.obolibrary.org/obo/GO_0005630 CHEBI:6714 biolink:ChemicalSubstance (+)-medicarpin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6714 chebi_ph7_3 GO:0005639 biolink:CellularComponent integral component of nuclear inner membrane The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to nuclear inner membrane http://purl.obolibrary.org/obo/GO_0005639 NCBITaxon:1549675 biolink:OrganismalEntity Galloanserae go-plus.json Galloanseri|ducks, geese, chickens, fowl, quail, currasows and allies http://purl.obolibrary.org/obo/NCBITaxon_1549675 GO:0005648 biolink:CellularComponent obsolete importin, beta-subunit OBSOLETE. (Was not defined before being made obsolete). go-plus.json karyopherin-beta1|importin, beta-subunit http://purl.obolibrary.org/obo/GO_0005648 GO:0005649 biolink:CellularComponent obsolete transportin OBSOLETE. (Was not defined before being made obsolete). go-plus.json karyopherin-beta2|transportin http://purl.obolibrary.org/obo/GO_0005649 GO:0005646 biolink:CellularComponent obsolete importin OBSOLETE. (Was not defined before being made obsolete). go-plus.json karyopherin|importin http://purl.obolibrary.org/obo/GO_0005646 GO:0005647 biolink:CellularComponent obsolete importin, alpha-subunit OBSOLETE. (Was not defined before being made obsolete). go-plus.json importin, alpha-subunit|karyopherin-alpha http://purl.obolibrary.org/obo/GO_0005647 GO:0005644 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005644 GO:0005645 biolink:CellularComponent obsolete RAN-binding protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json RAN-binding protein http://purl.obolibrary.org/obo/GO_0005645 GO:0005642 biolink:CellularComponent annulate lamellae Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER. go-plus.json http://purl.obolibrary.org/obo/GO_0005642 GO:0005643 biolink:CellularComponent nuclear pore A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. NIF_Subcellular:sao220861693|Wikipedia:Nuclear_pore go-plus.json nuclear pore complex|nuclear pore membrane protein|nucleopore|NPC http://purl.obolibrary.org/obo/GO_0005643 goslim_pir GO:0005640 biolink:CellularComponent nuclear outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. NIF_Subcellular:sao1617136075 go-plus.json perinuclear membrane|nucleus outer envelope http://purl.obolibrary.org/obo/GO_0005640 GO:0005641 biolink:CellularComponent nuclear envelope lumen The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide. go-plus.json nuclear intermembrane space|nuclear membrane lumen|perinuclear space http://purl.obolibrary.org/obo/GO_0005641 CL:0000806 biolink:Cell DN2 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive. go-plus.json TN2 cell|DN2 immature T cell|DN2 alpha-beta immature T-cell|TN2 thymocyte|DN2 alpha-beta immature T-lymphocyte|DN2 cell|preT.DN2.Th|double negative 2|DN2 alpha-beta immature T lymphocyte http://purl.obolibrary.org/obo/CL_0000806 CL:0000807 biolink:Cell DN3 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. go-plus.json DN3 immature T cell|TN3 cell|TN3 thymocyte|DN3 alpha-beta immature T-cell|DN3 alpha-beta immature T-lymphocyte|DN3 cell|double negative 3|preT.DN3.Th|DN3 alpha-beta immature T lymphocyte|early cortical thymocyte http://purl.obolibrary.org/obo/CL_0000807 CL:0000808 biolink:Cell DN4 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. go-plus.json DN4 immature T cell|DN4 alpha-beta immature T-lymphocyte|DN4 immature T-cell|DN4 cell|double negative 4|DN4 alpha-beta immature T lymphocyte|early cortical thymocyte|T.DN4.th http://purl.obolibrary.org/obo/CL_0000808 CL:0000809 biolink:Cell double-positive, alpha-beta thymocyte A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. go-plus.json late cortical thymocyte|double-positive, alpha-beta immature T lymphocyte|DP thymocyte|DP cell http://purl.obolibrary.org/obo/CL_0000809 CL:0000800 biolink:Cell mature gamma-delta T cell A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location. go-plus.json mature gamma-delta T-cell|mature gamma-delta T-lymphocyte|mature gamma-delta T lymphocyte http://purl.obolibrary.org/obo/CL_0000800 CL:0000801 biolink:Cell gamma-delta intraepithelial T cell A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. go-plus.json gamma-delta intraepithelial T-lymphocyte|IEL|gamma-delta intraepithelial T lymphocyte|intraepithelial lymphocyte|gamma-delta intraepithelial T-cell http://purl.obolibrary.org/obo/CL_0000801 CL:0000802 biolink:Cell CD8-alpha alpha positive, gamma-delta intraepithelial T cell A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive. go-plus.json IEL|CD8-positive, gamma-delta intraepithelial T lymphocyte|intraepithelial lymphocyte|CD8-positive, gamma-delta intraepithelial T-cell|CD8-positive, gamma-delta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/CL_0000802 CL:0000803 biolink:Cell CD4-negative CD8-negative gamma-delta intraepithelial T cell A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative. go-plus.json CD4-positive, gamma-delta intraepithelial T lymphocyte|IEL|intraepithelial lymphocyte|CD4-positive, gamma-delta intraepithelial T-cell|CD4-positive, gamma-delta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/CL_0000803 CL:0000805 biolink:Cell immature single positive thymocyte A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. go-plus.json immature single positive T lymphocyte|ISP|immature single positive T-lymphocyte|T.ISP.th|immature single positive T cell http://purl.obolibrary.org/obo/CL_0000805 CHEBI:6530 biolink:ChemicalSubstance longifolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_6530 chebi_ph7_3 CL:0000817 biolink:Cell precursor B cell A precursor B cell is a B cell with the phenotype CD10-positive. go-plus.json pre-B cell http://purl.obolibrary.org/obo/CL_0000817 CL:0000818 biolink:Cell transitional stage B cell An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen. go-plus.json transitional stage B-cell|transitional stage B-lymphocyte|T1 B cell|T2 B cell|T3 B cell|transitional B cell|transitional stage B lymphocyte http://purl.obolibrary.org/obo/CL_0000818 CL:0000819 biolink:Cell B-1 B cell A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive. go-plus.json B1 B-cell|B-1 cell|B1 B-lymphocyte|B-1 B lymphocyte|B1 cell|B1 B cell|B1 B lymphocyte|B-1 B-cell|B-1 B-lymphocyte http://purl.obolibrary.org/obo/CL_0000819 CL:0000810 biolink:Cell CD4-positive, alpha-beta thymocyte An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. go-plus.json CD4-positive, alpha-beta immature T-cell|SP CD4 cell|CD4-positive, alpha-beta immature T-lymphocyte|CD4-positive, alpha-beta immature T lymphocyte http://purl.obolibrary.org/obo/CL_0000810 CL:0000811 biolink:Cell CD8-positive, alpha-beta thymocyte An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. go-plus.json CD8-positive, alpha-beta immature T-cell|SP CD8 cell|CD8-positive, alpha-beta immature T-lymphocyte|CD8-positive, alpha-beta immature T lymphocyte|CD8-positive, alpha-beta immature T cell http://purl.obolibrary.org/obo/CL_0000811 CL:0000813 biolink:Cell memory T cell A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure. go-plus.json memory T-cell|memory T-lymphocyte|memory T lymphocyte http://purl.obolibrary.org/obo/CL_0000813 CL:0000814 biolink:Cell mature NK T cell A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response. go-plus.json mature NK T lymphocyte|mature natural killer T cell|mature natural killer T lymphocyte|mature NK T-cell|mature NKT cell|mature NK T-lymphocyte|mature natural killer T-cell|mature natural killer T-lymphocyte http://purl.obolibrary.org/obo/CL_0000814 CL:0000815 biolink:Cell regulatory T cell A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. go-plus.json suppressor T-cell|suppressor T-lymphocyte|regulatory T lymphocyte|suppressor T cell|suppressor T lymphocyte|regulatory T-cell|Treg|regulatory T-lymphocyte http://purl.obolibrary.org/obo/CL_0000815 CL:0000816 biolink:Cell immature B cell An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. go-plus.json immature B lymphocyte|newly formed B cell|immature B-cell|immature B-lymphocyte http://purl.obolibrary.org/obo/CL_0000816 GO:0015197 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015197 GO:0015198 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015198 GO:0015199 biolink:MolecularActivity amino-acid betaine transmembrane transporter activity Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid. go-plus.json glycine betaine/proline porter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|betaine transmembrane transporter activity|betaine/GABA:sodium symporter activity http://purl.obolibrary.org/obo/GO_0015199 GO:0015193 biolink:MolecularActivity L-proline transmembrane transporter activity Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid. Reactome:R-HSA-8870354 go-plus.json glycine betaine/proline porter activity|L-proline transporter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|L-proline permease activity http://purl.obolibrary.org/obo/GO_0015193 GO:0015194 biolink:MolecularActivity L-serine transmembrane transporter activity Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid. Reactome:R-HSA-8932980 go-plus.json threonine/serine:sodium symporter activity|L-serine permease activity|serine transporter activity|L-serine transporter activity http://purl.obolibrary.org/obo/GO_0015194 GO:0015195 biolink:MolecularActivity L-threonine transmembrane transporter activity Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid. go-plus.json threonine/serine:sodium symporter activity|L-threonine transporter activity|L-threonine permease activity http://purl.obolibrary.org/obo/GO_0015195 GO:0015196 biolink:MolecularActivity L-tryptophan transmembrane transporter activity Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. Reactome:R-HSA-8870352 go-plus.json valine/tyrosine/tryptophan permease activity|L-tryptophan transporter activity|L-tryptophan permease activity http://purl.obolibrary.org/obo/GO_0015196 CHEBI:6526 biolink:ChemicalSubstance Long-chain carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_6526 GO:0015180 biolink:MolecularActivity L-alanine transmembrane transporter activity Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid. go-plus.json L-alanine transporter activity http://purl.obolibrary.org/obo/GO_0015180 GO:0015181 biolink:MolecularActivity arginine transmembrane transporter activity Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane. RHEA:32143 go-plus.json histidine/arginine/lysine/ornithine porter activity|L-arginine transporter activity|arginine permease activity http://purl.obolibrary.org/obo/GO_0015181 CHEBI:134191 biolink:ChemicalSubstance 20-oxo-5-O-beta-mycaminosyltylactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_134191 GO:0015179 biolink:MolecularActivity L-amino acid transmembrane transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids. Reactome:R-HSA-212614 go-plus.json L-amino acid transporter activity http://purl.obolibrary.org/obo/GO_0015179 GO:0015175 biolink:MolecularActivity neutral amino acid transmembrane transporter activity Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. go-plus.json neutral amino acid transporter activity http://purl.obolibrary.org/obo/GO_0015175 CHEBI:6572 biolink:ChemicalSubstance L-lupinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_6572 GO:0015176 biolink:MolecularActivity obsolete holin OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases. go-plus.json holin http://purl.obolibrary.org/obo/GO_0015176 CHEBI:6570 biolink:ChemicalSubstance lupeol go-plus.json http://purl.obolibrary.org/obo/CHEBI_6570 chebi_ph7_3 GO:0015177 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015177 NCBITaxon:232378 biolink:OrganismalEntity Proteales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_232378 GO:0015178 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015178 GO:0015171 biolink:MolecularActivity amino acid transmembrane transporter activity Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. Reactome:R-HSA-379415|Reactome:R-HSA-5660910|Reactome:R-HSA-375790|Reactome:R-HSA-352371|Reactome:R-HSA-379426|Reactome:R-HSA-352232|Reactome:R-HSA-352379|Reactome:R-HSA-375405|Reactome:R-HSA-375417|Reactome:R-HSA-375487|Reactome:R-HSA-5659755|Reactome:R-HSA-352364|Reactome:R-HSA-5659734|Reactome:R-HSA-375473|Reactome:R-HSA-352029|Reactome:R-HSA-352385|Reactome:R-HSA-375776|Reactome:R-HSA-352174|Reactome:R-HSA-376200|Reactome:R-HSA-5660694|Reactome:R-HSA-5653850|Reactome:R-HSA-351963|Reactome:R-HSA-352059|Reactome:R-HSA-5660890|Reactome:R-HSA-352119|Reactome:R-HSA-375770|Reactome:R-HSA-351987|Reactome:R-HSA-352108|Reactome:R-HSA-212642|Reactome:R-HSA-379432|Reactome:R-HSA-375768|Reactome:R-HSA-352347|Reactome:R-HSA-352052|Reactome:R-HSA-5655702|Reactome:R-HSA-378513|Reactome:R-HSA-352158|Reactome:R-HSA-352107|Reactome:R-HSA-210439|Reactome:R-HSA-352354|Reactome:R-HSA-352103|Reactome:R-HSA-352191|Reactome:R-HSA-888592|Reactome:R-HSA-352136|Reactome:R-HSA-5659674|Reactome:R-HSA-352182|Reactome:R-HSA-8952726 go-plus.json amino acid/choline transmembrane transporter activity|hydroxy/aromatic amino acid permease activity|amino acid permease activity|amino acid transporter activity|general amino acid permease activity http://purl.obolibrary.org/obo/GO_0015171 GO:0015172 biolink:MolecularActivity acidic amino acid transmembrane transporter activity Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3. Reactome:R-HSA-372448 go-plus.json acidic amino acid transporter activity http://purl.obolibrary.org/obo/GO_0015172 CHEBI:6574 biolink:ChemicalSubstance lupulone go-plus.json http://purl.obolibrary.org/obo/CHEBI_6574 GO:0015173 biolink:MolecularActivity aromatic amino acid transmembrane transporter activity Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring. go-plus.json hydroxy/aromatic amino acid permease activity|valine/tyrosine/tryptophan permease activity|aromatic amino acid transporter activity http://purl.obolibrary.org/obo/GO_0015173 CHEBI:134185 biolink:ChemicalSubstance (S)-all-trans-4-hydroxyretinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134185 chebi_ph7_3 GO:0015174 biolink:MolecularActivity basic amino acid transmembrane transporter activity Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3. Reactome:R-HSA-8932851|Reactome:R-HSA-8959781 go-plus.json basic amino acid transporter activity|cationic amino acid transmembrane transporter activity|basic amino acid permease activity http://purl.obolibrary.org/obo/GO_0015174 CHEBI:134186 biolink:ChemicalSubstance all-trans-4-oxoretinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134186 chebi_ph7_3 GO:0015190 biolink:MolecularActivity L-leucine transmembrane transporter activity Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid. go-plus.json L-leucine transporter activity|leucine/isoleucine/valine porter activity|leucine/valine/isoleucine permease activity http://purl.obolibrary.org/obo/GO_0015190 GO:0015191 biolink:MolecularActivity L-methionine transmembrane transporter activity Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid. go-plus.json L-methionine transporter activity http://purl.obolibrary.org/obo/GO_0015191 GO:0015192 biolink:MolecularActivity L-phenylalanine transmembrane transporter activity Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid. go-plus.json L-phenylalanine transporter activity|L-phenylalanine permease activity http://purl.obolibrary.org/obo/GO_0015192 GO:0015186 biolink:MolecularActivity L-glutamine transmembrane transporter activity Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid. go-plus.json asparagine/glutamine permease activity http://purl.obolibrary.org/obo/GO_0015186 GO:0015187 biolink:MolecularActivity glycine transmembrane transporter activity Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid. go-plus.json proline/glycine/betaine:hydrogen/sodium symporter activity|glycine transporter activity|glycine betaine/proline porter activity http://purl.obolibrary.org/obo/GO_0015187 GO:0015188 biolink:MolecularActivity L-isoleucine transmembrane transporter activity Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid. go-plus.json leucine/isoleucine/valine porter activity|isoleucine/valine:sodium symporter activity|leucine/valine/isoleucine permease activity|L-isoleucine transporter activity http://purl.obolibrary.org/obo/GO_0015188 GO:0015189 biolink:MolecularActivity L-lysine transmembrane transporter activity Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid. go-plus.json lysine permease activity|L-lysine permease|histidine/arginine/lysine/ornithine porter activity http://purl.obolibrary.org/obo/GO_0015189 GO:0015182 biolink:MolecularActivity L-asparagine transmembrane transporter activity Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid. go-plus.json asparagine/glutamine permease activity|L-asparagine transporter activity http://purl.obolibrary.org/obo/GO_0015182 CHEBI:134198 biolink:ChemicalSubstance (R)-tembetarine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134198 chebi_ph7_3 GO:0015183 biolink:MolecularActivity L-aspartate transmembrane transporter activity Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid. go-plus.json glutamate/aspartate:sodium symporter activity|glutamate/aspartate porter activity|L-aspartate transporter activity http://purl.obolibrary.org/obo/GO_0015183 CHEBI:134199 biolink:ChemicalSubstance (S)-tembetarine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134199 chebi_ph7_3 GO:0015184 biolink:MolecularActivity L-cystine transmembrane transporter activity Enables the transfer of L-cystine from one side of a membrane to the other. Reactome:R-HSA-5340130 go-plus.json L-cystine transporter activity|cystine/diaminopimelate porter activity http://purl.obolibrary.org/obo/GO_0015184 CHEBI:134196 biolink:ChemicalSubstance (2R,5Z)-4-methyl-5-[2-(phosphonooxy)ethylidene]-2,5-dihydro-1,3-thiazole-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134196 GO:0015185 biolink:MolecularActivity gamma-aminobutyric acid transmembrane transporter activity Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA). go-plus.json 4-aminobutanoate transporter activity|betaine/GABA:sodium symporter activity|GABA transporter activity|4-aminobutyrate transporter activity http://purl.obolibrary.org/obo/GO_0015185 CHEBI:134197 biolink:ChemicalSubstance 3',5'-cyclic IMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134197 chebi_ph7_3 GO:0030798 biolink:MolecularActivity trans-aconitate 2-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine. MetaCyc:RXN0-2441|RHEA:14969|KEGG_REACTION:R05763|EC:2.1.1.144 go-plus.json S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030798 GO:0030799 biolink:BiologicalProcess obsolete regulation of cyclic nucleotide metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides. go-plus.json regulation of cyclic nucleotide metabolism http://purl.obolibrary.org/obo/GO_0030799 GO:0030796 biolink:MolecularActivity cycloartenol 24-C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+). RHEA:13137|KEGG_REACTION:R05760|MetaCyc:2.1.1.142-RXN|EC:2.1.1.142 go-plus.json sterol C-methyltransferase activity|S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030796 GO:0030797 biolink:MolecularActivity 24-methylenesterol C-methyltransferase activity Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+). KEGG_REACTION:R05776|RHEA:21044|MetaCyc:2.1.1.143-RXN|EC:2.1.1.143 go-plus.json 24-methylenelophenol C-24(1)-methyltransferase activity|24-methylenelophenol C-241-methyltransferase activity|SMT2|S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity|SMT(2) activity http://purl.obolibrary.org/obo/GO_0030797 NCBITaxon:30727 biolink:OrganismalEntity Cyprinoidei go-plus.json Cyprinoidea http://purl.obolibrary.org/obo/NCBITaxon_30727 GO:0015157 biolink:MolecularActivity oligosaccharide transmembrane transporter activity Enables the transfer of oligosaccharide from one side of a membrane to the other. go-plus.json endosomal oligosaccharide transporter http://purl.obolibrary.org/obo/GO_0015157 GO:0015158 biolink:MolecularActivity raffinose transmembrane transporter activity Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol. go-plus.json raffinose permease http://purl.obolibrary.org/obo/GO_0015158 GO:0015159 biolink:MolecularActivity polysaccharide transmembrane transporter activity Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json http://purl.obolibrary.org/obo/GO_0015159 GO:0030794 biolink:MolecularActivity (S)-coclaurine-N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine. RHEA:17409|MetaCyc:2.1.1.140-RXN|EC:2.1.1.140 go-plus.json S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030794 GO:0015153 biolink:MolecularActivity rhamnose transmembrane transporter activity Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids. RHEA:34995 go-plus.json ATP-dependent rhamnose transmembrane transporter activity|ATPase-coupled rhamnose transmembrane transporter activity|rhamnose-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015153 CHEBI:134161 biolink:ChemicalSubstance N-acylethanolamine 20:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134161 chebi_ph7_3 GO:0030795 biolink:MolecularActivity methyl jasmonate methylesterase activity Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate. RHEA:13349|MetaCyc:RXN-10768|EC:2.1.1.141 go-plus.json S-adenosyl-L-methionine:jasmonate O-methyltransferase activity|S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity|jasmonic acid carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0030795 GO:0015154 biolink:MolecularActivity disaccharide transmembrane transporter activity Enables the transfer of disaccharide from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015154 CHEBI:134162 biolink:ChemicalSubstance N-acylethanolamine 20:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134162 chebi_ph7_3 GO:0015155 biolink:MolecularActivity lactose transmembrane transporter activity Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals. go-plus.json lactose/glucose efflux transporter activity|lactose permease activity http://purl.obolibrary.org/obo/GO_0015155 GO:0030792 biolink:MolecularActivity methylarsonite methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate. MetaCyc:2.1.1.138-RXN|EC:2.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0030792 GO:0030793 biolink:MolecularActivity 3'-demethylstaurosporine O-methyltransferase activity Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine. KEGG_REACTION:R05757|RHEA:11696|MetaCyc:2.1.1.139-RXN|EC:2.1.1.139 go-plus.json 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity|S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity|staurosporine synthase activity http://purl.obolibrary.org/obo/GO_0030793 GO:0015156 biolink:MolecularActivity melibiose transmembrane transporter activity Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants. go-plus.json http://purl.obolibrary.org/obo/GO_0015156 GO:0030790 biolink:MolecularActivity chlorophenol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole. RHEA:18909|MetaCyc:2.1.1.136-RXN|EC:2.1.1.136 go-plus.json halogenated phenol O-methyltransferase activity|S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity|trichlorophenol O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030790 CHEBI:134165 biolink:ChemicalSubstance N-acylethanolamine 22:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134165 chebi_ph7_3 GO:0030791 biolink:MolecularActivity arsenite methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate. UM-BBD_reactionID:r0805|MetaCyc:2.1.1.137-RXN|EC:2.1.1.137|RHEA:15293|Reactome:R-HSA-5696213|Reactome:R-HSA-5696220 go-plus.json S-adenosyl-L-methionine:arsenic(III) methyltransferase activity|S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity|S-adenosyl-L-methionine:arsenite As-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030791 GO:0015150 biolink:MolecularActivity fucose transmembrane transporter activity Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose. go-plus.json http://purl.obolibrary.org/obo/GO_0015150 GO:0015151 biolink:MolecularActivity alpha-glucoside transmembrane transporter activity Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration. go-plus.json http://purl.obolibrary.org/obo/GO_0015151 GO:0015152 biolink:MolecularActivity glucose-6-phosphate transmembrane transporter activity Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6. go-plus.json http://purl.obolibrary.org/obo/GO_0015152 GO:0030789 biolink:MolecularActivity precorrin-3B C17-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4. RHEA:12761|MetaCyc:2.1.1.131-RXN|EC:2.1.1.131 go-plus.json S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity|CobJ|precorrin-3 methyltransferase activity|precorrin-3 methylase activity http://purl.obolibrary.org/obo/GO_0030789 GO:0015170 biolink:MolecularActivity propanediol transmembrane transporter activity Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects. go-plus.json http://purl.obolibrary.org/obo/GO_0015170 GO:0030787 biolink:MolecularActivity inositol 4-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). RHEA:23248|MetaCyc:2.1.1.129-RXN|EC:2.1.1.129|KEGG_REACTION:R01190 go-plus.json myo-inositol 4-O-methyltransferase activity|myo-inositol 6-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030787 GO:0030788 biolink:MolecularActivity precorrin-2 C20-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A. RHEA:16841|MetaCyc:2.1.1.130-RXN|EC:2.1.1.130|KEGG_REACTION:R03948 go-plus.json S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity|S-adenosyl-L-methionine--precorrin-2 methyltransferase activity http://purl.obolibrary.org/obo/GO_0030788 GO:0030785 biolink:MolecularActivity [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine. MetaCyc:2.1.1.127-RXN|EC:2.1.1.127|RHEA:50996 go-plus.json ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity|RuBisCO LSMT activity|RuBisCO methyltransferase activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity|ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity|ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030785 GO:0030786 biolink:MolecularActivity (RS)-norcoclaurine 6-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine. MetaCyc:2.1.1.128-RXN|RHEA:19941|EC:2.1.1.128 go-plus.json S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030786 CHEBI:134178 biolink:ChemicalSubstance all-trans-4-hydroxyretinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134178 chebi_ph7_3 CHEBI:134179 biolink:ChemicalSubstance volatile organic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_134179 GO:0015168 biolink:MolecularActivity glycerol transmembrane transporter activity Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. go-plus.json http://purl.obolibrary.org/obo/GO_0015168 GO:0015169 biolink:MolecularActivity glycerol-3-phosphate transmembrane transporter activity Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol. go-plus.json http://purl.obolibrary.org/obo/GO_0015169 GO:0015164 biolink:MolecularActivity glucuronoside transmembrane transporter activity Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate. go-plus.json glucuronide transporter activity http://purl.obolibrary.org/obo/GO_0015164 GO:0030783 biolink:MolecularActivity [cytochrome c]-methionine S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine. MetaCyc:2.1.1.123-RXN|EC:2.1.1.123 go-plus.json cytochrome c-methionine S-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030783 GO:0030784 biolink:MolecularActivity 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline. RHEA:17789|MetaCyc:2.1.1.116-RXN|EC:2.1.1.116 go-plus.json S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030784 GO:0015165 biolink:MolecularActivity pyrimidine nucleotide-sugar transmembrane transporter activity Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0015165 GO:0015166 biolink:MolecularActivity polyol transmembrane transporter activity Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol. Reactome:R-HSA-429571 go-plus.json sugar/polyol channel activity http://purl.obolibrary.org/obo/GO_0015166 GO:0030781 biolink:MolecularActivity 6-O-methylnorlaudanosoline 5'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline. RHEA:11892|MetaCyc:2.1.1.121-RXN|EC:2.1.1.121 go-plus.json S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030781 GO:0015167 biolink:MolecularActivity arabitol transmembrane transporter activity Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. go-plus.json arabinitol transporter activity http://purl.obolibrary.org/obo/GO_0015167 GO:0030782 biolink:MolecularActivity (S)-tetrahydroprotoberberine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine. MetaCyc:2.1.1.122-RXN|EC:2.1.1.122|RHEA:12805 go-plus.json S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity|tetrahydroprotoberberine cis-N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030782 CHEBI:134176 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134176 chebi_ph7_3 GO:0015160 biolink:MolecularActivity beta-glucan transmembrane transporter activity Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0015160 GO:0015161 biolink:MolecularActivity lipid III floppase activity Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi. TC:2.A.66.2.3|TC:2.A.66.2.12 go-plus.json capsule polysaccharide transporter activity|undecaprenol-pyrophosphate O-antigen flippase activity|capsular polysaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015161 GO:0030780 biolink:MolecularActivity 12-hydroxydihydrochelirubine 12-O-methyltransferase activity Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+). MetaCyc:2.1.1.120-RXN|RHEA:21092|EC:2.1.1.120|KEGG_REACTION:R04705 go-plus.json S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030780 GO:0015162 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015162 CHEBI:134175 biolink:ChemicalSubstance N-acylserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_134175 chebi_ph7_3 GO:0015163 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015163 CL:0000889 biolink:Cell myeloid suppressor cell An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0000889 CHEBI:17549 biolink:ChemicalSubstance 5-aminolevulinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17549 CHEBI:17548 biolink:ChemicalSubstance alginic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17548 CHEBI:17545 biolink:ChemicalSubstance (E)-indol-3-ylacetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_17545 chebi_ph7_3 CHEBI:17546 biolink:ChemicalSubstance (2Z)-5-isopropyl-2-methylhexa-2,5-dienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17546 chebi_ph7_3 CHEBI:17543 biolink:ChemicalSubstance 1-phospho-alpha-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17543 CHEBI:17544 biolink:ChemicalSubstance hydrogencarbonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17544 chebi_ph7_3 CHEBI:17541 biolink:ChemicalSubstance 2-carboxy-D-arabinitol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17541 CHEBI:17540 biolink:ChemicalSubstance methyl beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_17540 chebi_ph7_3 NCBITaxon:39107 biolink:OrganismalEntity Murinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_39107 CL:0000897 biolink:Cell CD4-positive, alpha-beta memory T cell A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell. go-plus.json CD4-positive, alpha-beta memory T-cell|T4.Mem.Sp|CD4-positive, alpha-beta memory T-lymphocyte|CD4-positive, alpha-beta memory T lymphocyte http://purl.obolibrary.org/obo/CL_0000897 CL:0000898 biolink:Cell naive T cell Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. go-plus.json naive T lymphocyte|naive T-cell|naive T-lymphocyte http://purl.obolibrary.org/obo/CL_0000898 CL:0000899 biolink:Cell T-helper 17 cell CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. go-plus.json helper T cell type 17|Th17 cell|T(H)-17 cell|IL-17-producing CD4+ T helper|Th17 T-cell|Th17 T-lymphocyte|T helper cells type 17|Th17 T cell|Th17 CD4+ T cell|Th17 T lymphocyte http://purl.obolibrary.org/obo/CL_0000899 CL:0000891 biolink:Cell foam cell A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/CL_0000891 CHEBI:17539 biolink:ChemicalSubstance 9-cis,11-trans-octadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17539 chebi_ph7_3 CL:0000892 biolink:Cell smooth muscle cell derived foam cell A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/CL_0000892 CL:0000893 biolink:Cell thymocyte An immature T cell located in the thymus. go-plus.json immature T-cell|immature T-lymphocyte|thymic lymphocyte|immature T cell|immature T lymphocyte http://purl.obolibrary.org/obo/CL_0000893 CHEBI:17536 biolink:ChemicalSubstance allantoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17536 chebi_ph7_3 CL:0000894 biolink:Cell DN1 thymic pro-T cell A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative. go-plus.json DN1 thymic pro-T-cell|DN1 thymic pro-T-lymphocyte|DN1 thymic progenitor T cell|preT.DN1.Th|DN1 thymocyte|double negative 1|DN1 thymic pro-T lymphocyte http://purl.obolibrary.org/obo/CL_0000894 CHEBI:17537 biolink:ChemicalSubstance Tyr-Arg go-plus.json http://purl.obolibrary.org/obo/CHEBI_17537 CHEBI:42504 biolink:ChemicalSubstance pentadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42504 CHEBI:17534 biolink:ChemicalSubstance 6-amino-2-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17534 CL:0000895 biolink:Cell naive thymus-derived CD4-positive, alpha-beta T cell An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. go-plus.json T.4Nve.Sp|naive thymus-derived CD4-positive, alpha-beta T-cell|naive thymus-derived CD4-positive, alpha-beta T-lymphocyte|Th0|naive thymus-derived CD4-positive, alpha-beta T lymphocyte|naive CD4+ T cell http://purl.obolibrary.org/obo/CL_0000895 CHEBI:17535 biolink:ChemicalSubstance L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17535 chebi_ph7_3 CL:0000896 biolink:Cell activated CD4-positive, alpha-beta T cell A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. go-plus.json activated CD4-positive, alpha-beta T-cell|activated CD4-positive, alpha-beta T-lymphocyte|activated CD4-positive, alpha-beta T lymphocyte http://purl.obolibrary.org/obo/CL_0000896 CHEBI:17532 biolink:ChemicalSubstance (S)-6-hydroxynicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17532 CHEBI:17533 biolink:ChemicalSubstance N-acetyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17533 CHEBI:17530 biolink:ChemicalSubstance L-arogenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17530 CHEBI:17531 biolink:ChemicalSubstance trans-beta-D-glucosyl-2-hydroxycinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17531 CL:0000864 biolink:Cell tissue-resident macrophage A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. go-plus.json resting histiocyte|fixed macrophage http://purl.obolibrary.org/obo/CL_0000864 CL:0000866 biolink:Cell thymic macrophage A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes. go-plus.json http://purl.obolibrary.org/obo/CL_0000866 NCBITaxon:2682482 biolink:OrganismalEntity Mastigamoebida go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2682482 CL:0000860 biolink:Cell classical monocyte A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. go-plus.json inflammatory monocyte http://purl.obolibrary.org/obo/CL_0000860 CL:0000861 biolink:Cell elicited macrophage A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. go-plus.json wandering histiocyte|free macrophage http://purl.obolibrary.org/obo/CL_0000861 CL:0000862 biolink:Cell suppressor macrophage A macrophage that suppresses immune responses. go-plus.json http://purl.obolibrary.org/obo/CL_0000862 CHEBI:17567 biolink:ChemicalSubstance O-alkylglycerone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17567 chebi_ph7_3 CL:0000863 biolink:Cell inflammatory macrophage An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. go-plus.json classically activated macrophage|M1 macrophage http://purl.obolibrary.org/obo/CL_0000863 CHEBI:17568 biolink:ChemicalSubstance uracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_17568 chebi_ph7_3 CHEBI:17566 biolink:ChemicalSubstance indole-3-acetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_17566 chebi_ph7_3 CHEBI:17563 biolink:ChemicalSubstance phthalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17563 chebi_ph7_3 CHEBI:17561 biolink:ChemicalSubstance L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17561 CHEBI:17562 biolink:ChemicalSubstance cytidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17562 chebi_ph7_3 CHEBI:17560 biolink:ChemicalSubstance 2,2'-iminodipropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17560 CL:0000875 biolink:Cell non-classical monocyte A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. go-plus.json patrolling monocyte|resident monocyte http://purl.obolibrary.org/obo/CL_0000875 CL:0000878 biolink:Cell central nervous system macrophage A tissue-resident macrophage found in the central nervous system. go-plus.json CNS macrophage http://purl.obolibrary.org/obo/CL_0000878 NCBITaxon:29760 biolink:OrganismalEntity Vitis vinifera go-plus.json Vitis vinifera subsp. vinifera|wine grape http://purl.obolibrary.org/obo/NCBITaxon_29760 CHEBI:17558 biolink:ChemicalSubstance quercitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17558 CHEBI:17559 biolink:ChemicalSubstance 3alpha(S)-strictosidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17559 CHEBI:17556 biolink:ChemicalSubstance phaseollidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17556 chebi_ph7_3 CHEBI:17555 biolink:ChemicalSubstance 1-alkyl-2-acetyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17555 CHEBI:17552 biolink:ChemicalSubstance GDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17552 CHEBI:17553 biolink:ChemicalSubstance O-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17553 CHEBI:17550 biolink:ChemicalSubstance UDP-N-acetyl-D-galactosamine 4-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17550 CHEBI:17551 biolink:ChemicalSubstance ecdysone palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17551 chebi_ph7_3 CL:0000842 biolink:Cell mononuclear cell A leukocyte with a single non-segmented nucleus in the mature form. go-plus.json peripheral blood mononuclear cell|mononuclear leukocyte http://purl.obolibrary.org/obo/CL_0000842 CL:0000843 biolink:Cell follicular B cell A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative. go-plus.json Fo B-cell|follicular B-cell|follicular B-lymphocyte|Fo B cell|follicular B lymphocyte http://purl.obolibrary.org/obo/CL_0000843 CL:0000844 biolink:Cell germinal center B cell A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. go-plus.json GC B cell|germinal center B-cell|GC B lymphocyte|germinal center B-lymphocyte|GC B-cell|germinal center B lymphocyte|GC B-lymphocyte http://purl.obolibrary.org/obo/CL_0000844 CL:0000845 biolink:Cell marginal zone B cell A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. go-plus.json MZ B-cell|MZ B-lymphocyte|marginal zone B-cell|marginal zone B-lymphocyte|MZ B cell|MZ B lymphocyte|marginal zone B lymphocyte http://purl.obolibrary.org/obo/CL_0000845 CL:0000847 biolink:Cell ciliated olfactory receptor neuron An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob. go-plus.json ciliated sensory neuron|ciliated olfactory sensory neuron http://purl.obolibrary.org/obo/CL_0000847 CHEBI:17509 biolink:ChemicalSubstance 5'-S-methyl-5'-thioadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17509 chebi_ph7_3 CHEBI:17507 biolink:ChemicalSubstance psychosine sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17507 CHEBI:17508 biolink:ChemicalSubstance 7,8-dihydroxykynurenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17508 CHEBI:17505 biolink:ChemicalSubstance alpha-D-galactosyl-(1->3)-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17505 chebi_ph7_3 CHEBI:17506 biolink:ChemicalSubstance 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17506 CHEBI:17503 biolink:ChemicalSubstance N-acyl-D-glutamates(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17503 chebi_ph7_3 CHEBI:17504 biolink:ChemicalSubstance 1-O-acyl-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17504 CL:0000840 biolink:Cell immature conventional dendritic cell An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low. go-plus.json immature myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000840 CHEBI:17501 biolink:ChemicalSubstance 3,3'-dimethoxystilbene-4,4'-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17501 chebi_ph7_3 CL:0000841 biolink:Cell mature conventional dendritic cell A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node. go-plus.json mature dendritic cell|mature myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000841 CHEBI:17502 biolink:ChemicalSubstance 2-methylpropanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_17502 chebi_ph7_3 CHEBI:17500 biolink:ChemicalSubstance 7alpha-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17500 chebi_ph7_3 UBERON:0020550 biolink:AnatomicalEntity auricular blood vessel A blood vessel that supplies or drains an ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_0020550 CL:0000855 biolink:Cell sensory hair cell Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. go-plus.json hair cell http://purl.obolibrary.org/obo/CL_0000855 CL:0000856 biolink:Cell neuromast hair cell Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. go-plus.json http://purl.obolibrary.org/obo/CL_0000856 CL:0000857 biolink:Cell slow muscle myoblast A skeletal muscle myoblast that differentiates into slow muscle fibers. go-plus.json http://purl.obolibrary.org/obo/CL_0000857 CL:0000850 biolink:Cell serotonergic neuron A neuron that releases serotonin as a neurotransmitter. go-plus.json 5-HT neuron|5-hydroxytryptamine neuron|serotinergic neuron http://purl.obolibrary.org/obo/CL_0000850 CL:0000851 biolink:Cell neuromast mantle cell Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded. go-plus.json http://purl.obolibrary.org/obo/CL_0000851 CL:0000852 biolink:Cell neuromast support cell Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells. go-plus.json http://purl.obolibrary.org/obo/CL_0000852 CL:0000828 biolink:Cell thromboblast A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates. go-plus.json http://purl.obolibrary.org/obo/CL_0000828 CL:0000829 biolink:Cell basophilic myeloblast A myeloblast committed to the basophil lineage. go-plus.json http://purl.obolibrary.org/obo/CL_0000829 CL:0000820 biolink:Cell B-1a B cell A B-1 B cell that has the phenotype CD5-positive. go-plus.json CD5(+) B1 cell|CD5-positive B1 cell|B-1a B lymphocyte|B1a B-cell|B1a B-lymphocyte|B-1a B-cell|B1a cell|B1a B cell|B-1a B-lymphocyte|B1a B lymphocyte|CD5+ B1 cell http://purl.obolibrary.org/obo/CL_0000820 CL:0000821 biolink:Cell B-1b B cell A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell. go-plus.json B-1b B lymphocyte|B1b B-cell|B1b B-lymphocyte|B-1b B-cell|B1b cell|B1b B cell|B-1b B-lymphocyte|B1b B lymphocyte http://purl.obolibrary.org/obo/CL_0000821 CL:0000822 biolink:Cell B-2 B cell A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. go-plus.json B-2 B-cell|B-2 B-lymphocyte|B2 B-cell|B2 B-lymphocyte|B-0 B cell|B-2 B lymphocyte|B2 cell|B2 B cell|B2 B lymphocyte http://purl.obolibrary.org/obo/CL_0000822 CL:0000823 biolink:Cell immature natural killer cell A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). go-plus.json p-NK|immature NK cell http://purl.obolibrary.org/obo/CL_0000823 CL:0000825 biolink:Cell pro-NK cell A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. go-plus.json pro-natural killer cell|preNK cell|null cell|NKP|natural killer cell progenitor http://purl.obolibrary.org/obo/CL_0000825 CL:0000826 biolink:Cell pro-B cell A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. go-plus.json pro-B-lymphocyte|pro-B lymphocyte|progenitor B-cell|progenitor B-lymphocyte|pre-B cell (Philadelphia nomenclature)|pre-pro B cell|progenitor B cell|pro-B-cell|progenitor B lymphocyte http://purl.obolibrary.org/obo/CL_0000826 CL:0000827 biolink:Cell pro-T cell A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. go-plus.json pro-T lymphocyte|DN1 cell|progenitor T cell|DN1 thymocyte|TN1 cell http://purl.obolibrary.org/obo/CL_0000827 CHEBI:17529 biolink:ChemicalSubstance kievitone hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17529 chebi_ph7_3 CHEBI:17527 biolink:ChemicalSubstance 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17527 chebi_ph7_3 CHEBI:17528 biolink:ChemicalSubstance all-trans-hexaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17528 CHEBI:17525 biolink:ChemicalSubstance testolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17525 CHEBI:17526 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17526 CHEBI:17524 biolink:ChemicalSubstance 6-alkylaminopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17524 chebi_ph7_3 CHEBI:17521 biolink:ChemicalSubstance (-)-quinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17521 CHEBI:17522 biolink:ChemicalSubstance alditol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17522 chebi_ph7_3 CHEBI:17520 biolink:ChemicalSubstance phenylthioacetohydroximic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17520 NCBITaxon:40117 biolink:OrganismalEntity Nitrospirae go-plus.json Thermodesulfovibrio group|Nitrospira group|Nitrospirota|Nitrospiraeota http://purl.obolibrary.org/obo/NCBITaxon_40117 CL:0000839 biolink:Cell myeloid lineage restricted progenitor cell A progenitor cell restricted to the myeloid lineage. go-plus.json myeloid progenitor cell http://purl.obolibrary.org/obo/CL_0000839 CL:0000831 biolink:Cell mast cell progenitor A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. go-plus.json colony forming unit mast cell|CFU-MC|CFU-Mast|MCP http://purl.obolibrary.org/obo/CL_0000831 CL:0000832 biolink:Cell eosinophilic myeloblast A myeloblast committed to the eosinophil lineage. go-plus.json http://purl.obolibrary.org/obo/CL_0000832 CL:0000833 biolink:Cell eosinophilic promyelocyte A promyelocyte committed to the eosinophil lineage. go-plus.json http://purl.obolibrary.org/obo/CL_0000833 CL:0000834 biolink:Cell neutrophil progenitor cell A progenitor cell of the neutrophil lineage. go-plus.json neutrophil stem cell http://purl.obolibrary.org/obo/CL_0000834 CL:0000835 biolink:Cell myeloblast The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. go-plus.json http://purl.obolibrary.org/obo/CL_0000835 CL:0000836 biolink:Cell promyelocyte A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0000836 CL:0000837 biolink:Cell hematopoietic multipotent progenitor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. go-plus.json MPP|hemopoietic progenitor cell http://purl.obolibrary.org/obo/CL_0000837 CL:0000838 biolink:Cell lymphoid lineage restricted progenitor cell A progenitor cell restricted to the lymphoid lineage. go-plus.json lymphoid progenitor cell http://purl.obolibrary.org/obo/CL_0000838 CHEBI:17519 biolink:ChemicalSubstance N-methyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17519 CHEBI:17516 biolink:ChemicalSubstance but-1-ene-1,2,4-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17516 CHEBI:17517 biolink:ChemicalSubstance phosphatidylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17517 CHEBI:17514 biolink:ChemicalSubstance cyanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17514 CHEBI:17515 biolink:ChemicalSubstance L-gamma-glutamyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17515 CHEBI:17512 biolink:ChemicalSubstance methyl 2-O-alpha-L-fucopyranosyl-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_17512 chebi_ph7_3 CL:0000830 biolink:Cell basophilic promyelocyte A promyelocyte committed to the basophil lineage. go-plus.json http://purl.obolibrary.org/obo/CL_0000830 CHEBI:17510 biolink:ChemicalSubstance dTDP-D-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17510 CHEBI:17511 biolink:ChemicalSubstance 3-O-L-alanyl-1-O-phosphatidylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17511 GO:0005736 biolink:CellularComponent RNA polymerase I complex RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. go-plus.json DNA-directed RNA polymerase I activity|DNA-directed RNA polymerase I complex http://purl.obolibrary.org/obo/GO_0005736 GO:0005737 biolink:CellularComponent cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. Wikipedia:Cytoplasm go-plus.json http://purl.obolibrary.org/obo/GO_0005737 goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_plant GO:0005734 biolink:CellularComponent obsolete box C + D snoRNP protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json box C + D snoRNP protein http://purl.obolibrary.org/obo/GO_0005734 GO:0005735 biolink:CellularComponent obsolete box H + ACA snoRNP protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json box H + ACA snoRNP protein http://purl.obolibrary.org/obo/GO_0005735 GO:0005732 biolink:CellularComponent sno(s)RNA-containing ribonucleoprotein complex A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA. go-plus.json small nucleolar ribonucleoprotein|small ribonucleoprotein|sRNP|snoRNP|small nucleolar ribonucleoprotein complex|small ribonucleoprotein protein complex http://purl.obolibrary.org/obo/GO_0005732 goslim_pir GO:0005733 biolink:CellularComponent obsolete small nucleolar RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json snoRNA|small nucleolar RNA http://purl.obolibrary.org/obo/GO_0005733 GO:0005730 biolink:CellularComponent nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. NIF_Subcellular:sao1820400233|Wikipedia:Nucleolus go-plus.json http://purl.obolibrary.org/obo/GO_0005730 goslim_generic|goslim_chembl|goslim_candida|goslim_yeast|goslim_plant|goslim_pir|goslim_drosophila|goslim_aspergillus GO:0005731 biolink:CellularComponent nucleolus organizer region A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed. Wikipedia:Nucleolus_organizer_region go-plus.json nucleolus organiser region|NOR|nucleolus organizer complex http://purl.obolibrary.org/obo/GO_0005731 CHEBI:42471 biolink:ChemicalSubstance forskolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_42471 chebi_ph7_3 NCBITaxon:5234 biolink:OrganismalEntity Tremellales go-plus.json jelly fungi http://purl.obolibrary.org/obo/NCBITaxon_5234 GO:0005739 biolink:CellularComponent mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. Wikipedia:Mitochondrion|NIF_Subcellular:sao1860313010 go-plus.json mitochondria http://purl.obolibrary.org/obo/GO_0005739 goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_candida|goslim_yeast|goslim_pir|goslim_plant GO:0005747 biolink:CellularComponent mitochondrial respiratory chain complex I A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. go-plus.json http://purl.obolibrary.org/obo/GO_0005747 PO:0000077 biolink:OntologyClass sclerenchyma cell A ground tissue cell (PO:0025030) with a lignified secondary cell wall. go-plus.json célula esclerenquimática (Spanish, exact)|厚膜組織 細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000077 GO:0005748 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005748 GO:0005745 biolink:CellularComponent m-AAA complex Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria. go-plus.json http://purl.obolibrary.org/obo/GO_0005745 GO:0005746 biolink:CellularComponent mitochondrial respirasome The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. go-plus.json mitochondrial respirasome|mitochondrial electron transport chain|mitochondrial respiratory supercomplex|mitochondrial respiratory chain supercomplex|mitochondrial respiratory chain http://purl.obolibrary.org/obo/GO_0005746 GO:0005743 biolink:CellularComponent mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. NIF_Subcellular:sao1371347282|Wikipedia:Inner_mitochondrial_membrane go-plus.json inner mitochondrion membrane|mitochondrion inner membrane|inner mitochondrial membrane http://purl.obolibrary.org/obo/GO_0005743 GO:0005744 biolink:CellularComponent TIM23 mitochondrial import inner membrane translocase complex The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. go-plus.json Tim23 complex|mitochondrial inner membrane pre-sequence translocase complex|mitochondrial inner membrane presequence translocase complex|mitochondrial inner membrane translocase complex http://purl.obolibrary.org/obo/GO_0005744 goslim_pir GO:0005741 biolink:CellularComponent mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. Wikipedia:Outer_mitochondrial_membrane|NIF_Subcellular:sao1289741256 go-plus.json outer mitochondrial membrane|outer mitochondrion membrane|mitochondrion outer membrane http://purl.obolibrary.org/obo/GO_0005741 GO:0005742 biolink:CellularComponent mitochondrial outer membrane translocase complex A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments. go-plus.json GIP complex|mitochondrion outer membrane translocase complex http://purl.obolibrary.org/obo/GO_0005742 GO:0005740 biolink:CellularComponent mitochondrial envelope The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0005740 goslim_candida|goslim_yeast CHEBI:42465 biolink:ChemicalSubstance ethanesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42465 CHEBI:17499 biolink:ChemicalSubstance hydrogen donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_17499 chebi_ph7_3 CHEBI:17497 biolink:ChemicalSubstance glycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17497 PO:0000084 biolink:OntologyClass plant sperm cell A gamete (PO:0025006) produced by an antheridium (PO:0025125) or a microgametophyte (PO:0025280). go-plus.json 植物精子細胞 (Japanese, exact)|male gamete (exact)|sperm cell (broad)|célula espermática o esperma (Spanish, exact)|microgamete (exact)|sperm nucleus (related) http://purl.obolibrary.org/obo/PO_0000084 CHEBI:17495 biolink:ChemicalSubstance cholesteryl beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_17495 chebi_ph7_3 GO:0005749 biolink:CellularComponent mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. go-plus.json mitochondrial fumarate reductase complex http://purl.obolibrary.org/obo/GO_0005749 CHEBI:17494 biolink:ChemicalSubstance CDP-4-dehydro-6-deoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17494 GO:0005714 biolink:CellularComponent early recombination nodule An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0005714 GO:0005715 biolink:CellularComponent late recombination nodule An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0005715 GO:0005712 biolink:CellularComponent chiasma A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over. Wikipedia:Chiasma_(genetics) go-plus.json http://purl.obolibrary.org/obo/GO_0005712 NCBITaxon:5206 biolink:OrganismalEntity Cryptococcus go-plus.json Filobasidiella|Cryptococcus http://purl.obolibrary.org/obo/NCBITaxon_5206 GO:0005713 biolink:CellularComponent recombination nodule An electron dense structure that is associated with meiotic chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0005713 NCBITaxon:5207 biolink:OrganismalEntity Cryptococcus neoformans go-plus.json Debaryomyces neoformans|Saccharomyces neoformans|Lipomyces neoformans|Blastomyces neoformans|Torulopsis neoformans|Torula neoformans|Filobasidiella neoformans http://purl.obolibrary.org/obo/NCBITaxon_5207 GO:0005710 biolink:CellularComponent obsolete metaphase chromosome OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins. go-plus.json metaphase chromosome http://purl.obolibrary.org/obo/GO_0005710 NCBITaxon:5204 biolink:OrganismalEntity Basidiomycota go-plus.json basidiomycetes|basidiomycetes http://purl.obolibrary.org/obo/NCBITaxon_5204 GO:0005711 biolink:CellularComponent obsolete meiotic chromosome OBSOLETE. A chromosome involved in the process of meiosis. go-plus.json meiotic chromosome http://purl.obolibrary.org/obo/GO_0005711 PO:0000071 biolink:OntologyClass companion cell A parenchyma cell (PO:0000074) that is adjacent to a sieve tube element (PO:0000289) and arises from the same phloem mother cell (PO:0000400) as the sieve tube element. go-plus.json 伴細胞 (Japanese, exact)|célula acompañiante (Spanish, exact)|minor vein companion cell (exact) http://purl.obolibrary.org/obo/PO_0000071 GO:0005718 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005718 PO:0000074 biolink:OntologyClass parenchyma cell A relatively unspecialized ground tissue cell with a nucleate protoplast. go-plus.json célula parenquimática (Spanish, exact)|柔組織細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000074 GO:0005719 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005719 GO:0005716 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005716 PO:0000075 biolink:OntologyClass collenchyma cell An elongated plant cell with unevenly thickened non-lignified primary walls that is alive at maturity. go-plus.json célula colenquimática (Spanish, exact)|厚角組織 細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000075 GO:0005717 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005717 PO:0000055 biolink:OntologyClass bud An undeveloped shoot system (PO:0009006). go-plus.json yema (Spanish, exact)|adventitious bud (narrow)|芽 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000055 GO:0005725 biolink:CellularComponent intercalary heterochromatin Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0005725 CHEBI:66470 biolink:ChemicalSubstance (+)-sesamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_66470 chebi_ph7_3 GO:0005726 biolink:CellularComponent perichromatin fibrils Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts. go-plus.json http://purl.obolibrary.org/obo/GO_0005726 GO:0005723 biolink:CellularComponent alpha-heterochromatin A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization. go-plus.json http://purl.obolibrary.org/obo/GO_0005723 GO:0005724 biolink:CellularComponent obsolete nuclear telomeric heterochromatin OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0005724 GO:0005721 biolink:CellularComponent pericentric heterochromatin Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3. go-plus.json nuclear centric heterochromatin|nuclear cluster|centric heterochromatin|nuclear pericentric heterochromatin|centromeric heterochromatin http://purl.obolibrary.org/obo/GO_0005721 GO:0005722 biolink:CellularComponent beta-heterochromatin A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization. go-plus.json http://purl.obolibrary.org/obo/GO_0005722 GO:0005720 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005720 PO:0000062 biolink:OntologyClass stomatal initial cell An epidermal initial cell (PO:0000349) that undergoes several rounds of uneven division, each time giving rise to a larger daughter cell that differentiates into an epidermal ground cell and a smaller daughter cell that remains meristematic, until the meristematic cell (PO:0004010) differentiates into a guard mother cell (PO:0000351). go-plus.json 気孔始原細胞 (Japanese, exact)|stomatal initial (exact)|inicial estomática (meristemoide inicial) (Spanish, exact)|stomatal meristemoid (exact) http://purl.obolibrary.org/obo/PO_0000062 GO:0005729 biolink:CellularComponent 2-micrometer circle DNA A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies. go-plus.json http://purl.obolibrary.org/obo/GO_0005729 GO:0005727 biolink:CellularComponent extrachromosomal circular DNA Circular DNA structures that are not part of a chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0005727 goslim_metagenomics GO:0005728 biolink:CellularComponent extrachromosomal rDNA circle Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats. go-plus.json extrachromosomal ribosomal DNA circle http://purl.obolibrary.org/obo/GO_0005728 CHEBI:17470 biolink:ChemicalSubstance 2-O-caffeoylglucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17470 NCBITaxon:5268 biolink:OrganismalEntity Ustilaginaceae go-plus.json Mycosyringaceae http://purl.obolibrary.org/obo/NCBITaxon_5268 NCBITaxon:5269 biolink:OrganismalEntity Ustilago go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5269 NCBITaxon:5270 biolink:OrganismalEntity Ustilago maydis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5270 UBERON:0005032 biolink:AnatomicalEntity mucosa of lower lip A mucosa that is part of a lower lip [Automatically generated definition]. go-plus.json mucosa of organ of lower lip|lower lip organ mucosa|lower labial mucosa|lower lip mucosa of organ|organ mucosa of lower lip|lower lip mucous membrane|lower lip mucosa|mucous membrane of lower lip http://purl.obolibrary.org/obo/UBERON_0005032 UBERON:0005033 biolink:AnatomicalEntity mucosa of gallbladder A mucosa that is part of a gallbladder [Automatically generated definition]. go-plus.json gallbladder organ mucosa|gall bladder mucosa|gall bladder mucosa of organ|mucous membrane of gallbladder|gall bladder mucous membrane|tunica mucosa (vesica biliaris)|mucosa of organ of gallbladder|organ mucosa of gall bladder|gallbladder mucosa|tunica mucosa vesicae biliaris|gall bladder organ mucosa|organ mucosa of gallbladder|gallbladder mucosa of organ|mucosa of organ of gall bladder|gallbladder mucous membrane|mucosa of gall bladder|mucous membrane of gall bladder http://purl.obolibrary.org/obo/UBERON_0005033 UBERON:0005031 biolink:AnatomicalEntity mucosa of upper lip A mucosa that is part of a upper lip [Automatically generated definition]. go-plus.json mucosa of organ of upper lip|upper labial mucosa|upper lip organ mucosa|organ mucosa of upper lip|upper lip mucosa of organ|upper lip mucous membrane|upper lip mucosa|mucous membrane of upper lip http://purl.obolibrary.org/obo/UBERON_0005031 CHEBI:42438 biolink:ChemicalSubstance 2-methoxy-4-vinylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42438 chebi_ph7_3 CHEBI:17468 biolink:ChemicalSubstance (4-bromophenylsulfanyl)pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17468 chebi_ph7_3 CHEBI:17469 biolink:ChemicalSubstance N-adenylylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17469 CHEBI:17466 biolink:ChemicalSubstance GDP-D-mannuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17466 chebi_ph7_3 CHEBI:17467 biolink:ChemicalSubstance 4-(dimethylamino)phenylazoxybenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17467 chebi_ph7_3 CHEBI:17464 biolink:ChemicalSubstance L-galactono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17464 chebi_ph7_3 CHEBI:17465 biolink:ChemicalSubstance phaseollidin hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17465 chebi_ph7_3 UBERON:0005038 biolink:AnatomicalEntity mucosa of segmental bronchus A mucosa that is part of a segmental bronchus [Automatically generated definition]. go-plus.json tertiary bronchus mucosa of organ|organ mucosa of tertiary bronchus|segmental bronchial mucosa|mucosa of organ of segmental bronchus|tertiary bronchus mucosa|tertiary bronchus mucous membrane|mucous membrane of segmental bronchus|segmental bronchus organ mucosa|segmental bronchus mucosa of organ|mucous membrane of tertiary bronchus|segmental bronchus mucous membrane|mucosa of tertiary bronchus|tertiary bronchus organ mucosa|mucosa of organ of tertiary bronchus|segmental bronchus mucosa|organ mucosa of segmental bronchus http://purl.obolibrary.org/obo/UBERON_0005038 UBERON:0005039 biolink:AnatomicalEntity mucosa of bronchiole A mucosa that is part of a bronchiole [Automatically generated definition]. go-plus.json organ mucosa of lobular bronchiole|lobular bronchiole organ mucosa|mucosa of organ of bronchiole|bronchiole organ mucosa|mucous membrane of bronchiole|mucosa of organ of lobular bronchiole|bronchiole mucosa of organ|mucosa of lobular bronchiole|lobular bronchiole mucosa|mucous membrane of lobular bronchiole|bronchiole mucous membrane|lobular bronchiole mucosa of organ|bronchiole mucosa|lobular bronchiole mucous membrane|organ mucosa of bronchiole http://purl.obolibrary.org/obo/UBERON_0005039 CHEBI:17460 biolink:ChemicalSubstance lipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17460 chebi_ph7_3 UBERON:0005037 biolink:AnatomicalEntity mucosa of lobar bronchus A mucosa that is part of a lobar bronchus [Automatically generated definition]. go-plus.json mucosa of secondary bronchus|lobar bronchus mucosa of organ|mucous membrane of secondary bronchus|secondary bronchus mucosa|secondary bronchus mucosa of organ|lobar bronchus mucous membrane|lobar bronchus mucosa|secondary bronchus mucous membrane|organ mucosa of lobar bronchus|organ mucosa of secondary bronchus|secondary bronchus organ mucosa|lobar bronchial mucosa|mucosa of organ of lobar bronchus|lobar bronchus organ mucosa|mucosa of organ of secondary bronchus|mucous membrane of lobar bronchus http://purl.obolibrary.org/obo/UBERON_0005037 GO:0005703 biolink:CellularComponent polytene chromosome puff A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0005703 GO:0005704 biolink:CellularComponent polytene chromosome band A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band. go-plus.json http://purl.obolibrary.org/obo/GO_0005704 GO:0005701 biolink:CellularComponent polytene chromosome chromocenter A region at which the centric regions of polytene chromosomes are joined together. go-plus.json polytene chromosome chromocentre http://purl.obolibrary.org/obo/GO_0005701 GO:0005702 biolink:CellularComponent polytene chromosome weak point A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization. go-plus.json constriction http://purl.obolibrary.org/obo/GO_0005702 GO:0005700 biolink:CellularComponent polytene chromosome A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible. Wikipedia:Polytene_chromosome go-plus.json http://purl.obolibrary.org/obo/GO_0005700 UBERON:0005024 biolink:AnatomicalEntity mucosa of soft palate A mucosa that is part of a soft palate [Automatically generated definition]. go-plus.json soft palate mucosa|soft palate mucosa of organ|organ mucosa of soft palate|soft palate mucous membrane|soft palate organ mucosa|mucous membrane of soft palate|mucosa of organ of soft palate http://purl.obolibrary.org/obo/UBERON_0005024 UBERON:0005022 biolink:AnatomicalEntity mucosa of nasopharynx A mucosa that is part of a nasopharynx [Automatically generated definition]. go-plus.json nasal part of pharynx mucosa|nasopharynx mucosa|mucosa of organ of rhinopharynx|nasopharynx mucosa of organ|organ mucosa of nasopharynx|mucosa of rhinopharynx|mucous membrane of rhinopharynx|nasal part of pharynx mucosa of organ|organ mucosa of nasal part of pharynx|nasopharynx mucous membrane|rhinopharynx mucosa of organ|rhinopharynx organ mucosa|nasal part of pharynx mucous membrane|nasal part of pharynx organ mucosa|rhinopharynx mucous membrane|nasopharynx organ mucosa|mucous membrane of nasopharynx|organ mucosa of rhinopharynx|mucous membrane of nasal part of pharynx|mucosa of nasal part of pharynx|mucosa of organ of nasopharynx|rhinopharynx mucosa|mucosa of organ of nasal part of pharynx http://purl.obolibrary.org/obo/UBERON_0005022 CHEBI:17459 biolink:ChemicalSubstance D-iditol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17459 chebi_ph7_3 UBERON:0005020 biolink:AnatomicalEntity mucosa of tongue A mucosa that is part of a tongue [Automatically generated definition]. go-plus.json lingual mucosa|mucosa of organ of tongue|mucous membrane of tongue|tongue organ mucosa|tunica mucosa linguae|tongue mucosa of organ|tongue mucous membrane|tongue mucosa|organ mucosa of tongue http://purl.obolibrary.org/obo/UBERON_0005020 CHEBI:17457 biolink:ChemicalSubstance 14'-apo-beta-carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17457 chebi_ph7_3 CHEBI:17458 biolink:ChemicalSubstance N-methyltyramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17458 CHEBI:17455 biolink:ChemicalSubstance N-(2,3-dihydroxybenzoyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17455 CHEBI:17456 biolink:ChemicalSubstance dithioerythritol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17456 chebi_ph7_3 CHEBI:17453 biolink:ChemicalSubstance methylmalonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17453 chebi_ph7_3 GO:0005709 biolink:CellularComponent obsolete prophase chromosome OBSOLETE. A chromosome found in the cell during prophase. go-plus.json prophase chromosome http://purl.obolibrary.org/obo/GO_0005709 CHEBI:17454 biolink:ChemicalSubstance UDP-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17454 GO:0005707 biolink:CellularComponent obsolete interphase chromosome OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently. go-plus.json interphase chromosome http://purl.obolibrary.org/obo/GO_0005707 GO:0005708 biolink:CellularComponent obsolete mitotic chromosome OBSOLETE. A chromosome involved in the process of mitosis. go-plus.json mitotic chromosome http://purl.obolibrary.org/obo/GO_0005708 GO:0005705 biolink:CellularComponent polytene chromosome interband A stretch of less tightly packed chromatin along the polytene chromosome, found between bands. go-plus.json http://purl.obolibrary.org/obo/GO_0005705 UBERON:0005026 biolink:AnatomicalEntity mucosa of middle ear A mucosa that is part of a middle ear [Automatically generated definition]. go-plus.json mucosa of organ of middle ear|middle ear mucosa|mucous membrane of middle ear|middle ear mucosa of organ|middle ear mucous membrane|tunica mucosa cavitatis tympanicae|middle ear organ mucosa|organ mucosa of middle ear|mucosa of tympanic cavity http://purl.obolibrary.org/obo/UBERON_0005026 CHEBI:17450 biolink:ChemicalSubstance cis-4-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17450 GO:0005706 biolink:CellularComponent polytene chromosome ectopic fiber A thread-like connection joining two regions of ectopically paired polytene chromosomes. go-plus.json polytene chromosome ectopic fibre http://purl.obolibrary.org/obo/GO_0005706 CHEBI:17491 biolink:ChemicalSubstance S-(2-hydroxyacyl)glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17491 CHEBI:17490 biolink:ChemicalSubstance O-palmitoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17490 chebi_ph7_3 UBERON:0005012 biolink:AnatomicalEntity mucosa of left uterine tube A mucosa that is part of a left uterine tube [Automatically generated definition]. go-plus.json left uterine tube mucous membrane|left fallopian tube mucosa of organ|organ mucosa of left fallopian tube|left uterine tube organ mucosa|left oviduct organ mucosa|organ mucosa of left oviduct|left fallopian tube mucous membrane|left fallopian tube mucosa|mucous membrane of left uterine tube|mucosa of organ of left oviduct|mucosa of organ of left uterine tube|mucous membrane of left fallopian tube|left uterine tube mucosa|mucosa of left fallopian tube|left oviduct mucosa|mucosa of left oviduct|mucous membrane of left oviduct|mucosa of organ of left fallopian tube|left oviduct mucosa of organ|left uterine tube mucosa of organ|organ mucosa of left uterine tube|left fallopian tube organ mucosa|left oviduct mucous membrane http://purl.obolibrary.org/obo/UBERON_0005012 UBERON:0005013 biolink:AnatomicalEntity mucosa of male urethra A mucosa that is part of a male urethra [Automatically generated definition]. go-plus.json male urethra mucosa|mucosa of organ of male urethra|mucous membrane of male urethra|male urethra mucosa of organ|male urethra organ mucosa|male urethra mucous membrane|organ mucosa of male urethra http://purl.obolibrary.org/obo/UBERON_0005013 UBERON:0005010 biolink:AnatomicalEntity mucosa of neck of urinary bladder A mucosa that is part of a neck of urinary bladder [Automatically generated definition]. go-plus.json mucosa of organ of bladder neck|organ mucosa of neck of urinary bladder|neck of urinary bladder mucosa of organ|bladder neck mucosa|neck of bladder mucosa|mucosa of bladder neck|mucosa of organ of vesical neck|mucous membrane of bladder neck|mucosa of organ of urinary bladder neck|neck of urinary bladder mucous membrane|neck of bladder mucosa of organ|organ mucosa of neck of bladder|bladder neck mucosa of organ|mucosa of vesical neck|neck of urinary bladder mucosa|mucosa of urinary bladder neck|mucous membrane of vesical neck|mucous membrane of urinary bladder neck|neck of bladder mucous membrane|bladder neck mucous membrane|vesical neck mucosa of organ|urinary bladder neck mucosa of organ|vesical neck organ mucosa|mucous membrane of neck of urinary bladder|vesical neck mucous membrane|urinary bladder neck mucous membrane|bladder neck organ mucosa|organ mucosa of bladder neck|neck of bladder organ mucosa|mucosa of organ of neck of urinary bladder|mucous membrane of neck of bladder|mucosa of neck of bladder|organ mucosa of vesical neck|neck of urinary bladder organ mucosa|organ mucosa of urinary bladder neck|urinary bladder neck mucosa|mucosa of organ of neck of bladder|vesical neck mucosa http://purl.obolibrary.org/obo/UBERON_0005010 UBERON:0005011 biolink:AnatomicalEntity mucosa of right uterine tube A mucosa that is part of a right uterine tube [Automatically generated definition]. go-plus.json organ mucosa of right fallopian tube|organ mucosa of right oviduct|right oviduct mucosa of organ|right fallopian tube organ mucosa|mucosa of organ of right uterine tube|right oviduct mucosa|right oviduct mucous membrane|mucous membrane of right uterine tube|mucosa of organ of right fallopian tube|right uterine tube organ mucosa|right uterine tube mucosa of organ|mucosa of right fallopian tube|mucous membrane of right fallopian tube|mucous membrane of right oviduct|right uterine tube mucous membrane|mucosa of right oviduct|right fallopian tube mucosa|right fallopian tube mucosa of organ|right oviduct organ mucosa|mucosa of organ of right oviduct|right fallopian tube mucous membrane|organ mucosa of right uterine tube|right uterine tube mucosa http://purl.obolibrary.org/obo/UBERON_0005011 CHEBI:17488 biolink:ChemicalSubstance scopoletin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17488 chebi_ph7_3 CHEBI:17489 biolink:ChemicalSubstance 3',5'-cyclic AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17489 CHEBI:17486 biolink:ChemicalSubstance (S)-atropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17486 UBERON:0005019 biolink:AnatomicalEntity mucosa of palate A mucosa that is part of a palate [Automatically generated definition]. go-plus.json oral roof mucosa of organ|organ mucosa of oral roof|palate mucosa|roof of mouth mucous membrane|oral roof organ mucosa|oral roof mucous membrane|roof of mouth organ mucosa|mucosa of organ of palate|mucous membrane of palate|mucous membrane of roof of mouth|mucosa of roof of mouth|palate mucosa of organ|mucous membrane of oral roof|oral roof mucosa|mucosa of organ of roof of mouth|mucosa of oral roof|palate organ mucosa|roof of mouth mucosa|palate mucous membrane|mucosa of organ of oral roof|organ mucosa of palate|organ mucosa of roof of mouth|roof of mouth mucosa of organ http://purl.obolibrary.org/obo/UBERON_0005019 CHEBI:17484 biolink:ChemicalSubstance benzyl isothiocyanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17484 chebi_ph7_3 CHEBI:17485 biolink:ChemicalSubstance homocystine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17485 UBERON:0005014 biolink:AnatomicalEntity mucosa of female urethra A mucosa that is part of a female urethra [Automatically generated definition]. go-plus.json female urethra mucosa|mucosa of organ of female urethra|mucous membrane of female urethra|female urethra mucosa of organ|female urethra organ mucosa|female urethra mucous membrane|organ mucosa of female urethra http://purl.obolibrary.org/obo/UBERON_0005014 CHEBI:17482 biolink:ChemicalSubstance L-cystathionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17482 NCBITaxon:5257 biolink:OrganismalEntity Ustilaginomycetes go-plus.json Ustilaginomycetidae http://purl.obolibrary.org/obo/NCBITaxon_5257 NCBITaxon:5258 biolink:OrganismalEntity Pucciniales go-plus.json rusts|rust fungi|Uredinales http://purl.obolibrary.org/obo/NCBITaxon_5258 CHEBI:354984 biolink:ChemicalSubstance candicidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_354984 UBERON:0005001 biolink:AnatomicalEntity mucosa of common hepatic duct A mucosa that is part of a common hepatic duct [Automatically generated definition]. go-plus.json organ mucosa of hepatic duct|common hepatic duct organ mucosa|common hepatic duct mucous membrane|mucosa of organ of hepatic duct|hepatic duct organ mucosa|mucous membrane of common hepatic duct|mucosa of hepatic duct|mucous membrane of hepatic duct|common hepatic duct mucosa|hepatic duct mucosa of organ|mucosa of organ of common hepatic duct|hepatic duct mucous membrane|common hepatic ductal mucosa|hepatic duct mucosa|organ mucosa of common hepatic duct|common hepatic duct mucosa of organ http://purl.obolibrary.org/obo/UBERON_0005001 UBERON:0005002 biolink:AnatomicalEntity mucosa of right hepatic duct A mucosa that is part of a right hepatic duct [Automatically generated definition]. go-plus.json right hepatic duct mucosa|mucosa of organ of right hepatic duct|right hepatic ductal mucosa|mucous membrane of right hepatic duct|right hepatic duct mucosa of organ|right hepatic duct organ mucosa|right hepatic duct mucous membrane|organ mucosa of right hepatic duct http://purl.obolibrary.org/obo/UBERON_0005002 UBERON:0005000 biolink:AnatomicalEntity mucosa of common bile duct A mucosa that is part of a common bile duct [Automatically generated definition]. go-plus.json mucosa of organ of common bile duct|organ mucosa of ductus choledochus (biliaris)|ductus choledochus (biliaris) mucosa of organ|mucous membrane of common bile duct|common bile duct mucosa|common bile duct mucosa of organ|ductus choledochus (biliaris) mucous membrane|ductus choledochus (biliaris) mucosa|common bile duct mucous membrane|common bile ductal mucosa|mucous membrane of ductus choledochus (biliaris)|organ mucosa of common bile duct|mucosa of ductus choledochus (biliaris)|common bile duct organ mucosa|mucosa of organ of ductus choledochus (biliaris)|ductus choledochus (biliaris) organ mucosa http://purl.obolibrary.org/obo/UBERON_0005000 CHEBI:17479 biolink:ChemicalSubstance enol-oxaloacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17479 chebi_ph7_3 CHEBI:17477 biolink:ChemicalSubstance uracil-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17477 NCBITaxon:5267 biolink:OrganismalEntity Ustilaginales go-plus.json smuts|smut fungi http://purl.obolibrary.org/obo/NCBITaxon_5267 CHEBI:17478 biolink:ChemicalSubstance aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17478 chebi_ph7_3 CHEBI:17475 biolink:ChemicalSubstance aminomalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17475 CHEBI:17476 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17476 NCBITaxon:5262 biolink:OrganismalEntity Pucciniaceae go-plus.json Pucciniosiraceae http://purl.obolibrary.org/obo/NCBITaxon_5262 CHEBI:17473 biolink:ChemicalSubstance 1-alkyl-2-acetyl-3-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17473 chebi_ph7_3 UBERON:0005005 biolink:AnatomicalEntity mucosa of left ureter A mucosa that is part of a left ureter [Automatically generated definition]. go-plus.json left ureter mucosa of organ|organ mucosa of left ureter|left ureter mucous membrane|left ureter mucosa|mucous membrane of left ureter|left ureteral mucosa|mucosa of organ of left ureter|left ureter organ mucosa http://purl.obolibrary.org/obo/UBERON_0005005 UBERON:0005006 biolink:AnatomicalEntity mucosa of renal pelvis A mucosa that is part of a renal pelvis [Automatically generated definition]. go-plus.json mucosa of organ of kidney pelvis|organ mucosa of renal pelvis|mucosa of organ of pelvis of ureter|pelvis of ureter mucosa|mucosa of pelvis of ureter|kidney pelvis mucosa|mucous membrane of pelvis of ureter|organ mucosa of kidney pelvis|kidney pelvis mucosa of organ|mucosa of organ of renal pelvis|pelvis of ureter mucosa of organ|tunica mucosa pelvis renalis|renal pelvic mucosa|renal pelvis organ mucosa|kidney pelvis mucous membrane|mucous membrane of renal pelvis|pelvis of ureter mucous membrane|renal pelvis mucosa of organ|pelvis of ureter organ mucosa|organ mucosa of pelvis of ureter|kidney pelvis organ mucosa|renal pelvis mucous membrane|mucous membrane of kidney pelvis|mucosa of kidney pelvis|renal pelvis mucosa http://purl.obolibrary.org/obo/UBERON_0005006 CHEBI:17474 biolink:ChemicalSubstance estrone 3-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17474 UBERON:0005003 biolink:AnatomicalEntity mucosa of left hepatic duct A mucosa that is part of a left hepatic duct [Automatically generated definition]. go-plus.json left hepatic duct mucous membrane|left hepatic ductal mucosa|left hepatic duct organ mucosa|mucous membrane of left hepatic duct|mucosa of organ of left hepatic duct|left hepatic duct mucosa|left hepatic duct mucosa of organ|organ mucosa of left hepatic duct http://purl.obolibrary.org/obo/UBERON_0005003 UBERON:0005004 biolink:AnatomicalEntity mucosa of right ureter A mucosa that is part of a right ureter [Automatically generated definition]. go-plus.json right ureteral mucosa|organ mucosa of right ureter|right ureter organ mucosa|mucosa of organ of right ureter|mucous membrane of right ureter|right ureter mucosa|right ureter mucosa of organ|right ureter mucous membrane http://purl.obolibrary.org/obo/UBERON_0005004 PO:0000002 biolink:OntologyClass anther wall A microsporangium wall (PO:0025307) that is part of an anther (PO:0009066). go-plus.json pollen sac wall (exact)|Zea anther wall (narrow)|pared de la antera (Spanish, exact)|葯壁 (Japanese, exact)|Poaceae anther wall (narrow) http://purl.obolibrary.org/obo/PO_0000002 GO:0030778 biolink:MolecularActivity columbamine O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine. KEGG_REACTION:R03721|MetaCyc:2.1.1.118-RXN|EC:2.1.1.118|RHEA:15373 go-plus.json S-adenosyl-L-methionine:columbamine O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030778 PO:0000003 biolink:OntologyClass whole plant A plant structure (PO:0005679) which is a whole organism. go-plus.json prothalli (narrow)|shrub (narrow)|vine (narrow)|herb (narrow)|colony (related)|植物体全体 (Japanese, exact)|frutices (narrow)|planta entera (Spanish, exact)|suffrutices (narrow)|liana (narrow)|ramet (broad)|woody clump (narrow)|prothallus (narrow)|tree (narrow)|frutex (narrow)|prothallium (narrow)|suffrutex (narrow)|clonal colony (related)|sporophyte (narrow)|gametophyte (narrow)|seedling (narrow)|genet (broad)|bush (narrow) http://purl.obolibrary.org/obo/PO_0000003 GO:0030779 biolink:MolecularActivity 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+). KEGG_REACTION:R04707|MetaCyc:2.1.1.119-RXN|EC:2.1.1.119|RHEA:18541 go-plus.json S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030779 GO:0030776 biolink:MolecularActivity (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline. RHEA:13005|MetaCyc:2.1.1.115-RXN|EC:2.1.1.115 go-plus.json norreticuline N-methyltransferase activity|S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity|(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030776 GO:0030777 biolink:MolecularActivity (S)-scoulerine 9-O-methyltransferase activity Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+). RHEA:23808|KEGG_REACTION:R03835|MetaCyc:2.1.1.117-RXN|EC:2.1.1.117 go-plus.json S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity|S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030777 GO:0030774 biolink:MolecularActivity anthranilate N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+). MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R00984|RHEA:12180|EC:2.1.1.111 go-plus.json S-adenosyl-L-methionine:anthranilate N-methyltransferase activity|anthranilic acid N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030774 GO:0030775 biolink:MolecularActivity glucuronoxylan 4-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate. RHEA:20413|MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN|EC:2.1.1.112 go-plus.json S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030775 GO:0015139 biolink:MolecularActivity alpha-ketoglutarate transmembrane transporter activity Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle. Reactome:R-HSA-372480 go-plus.json 2-oxoglutarate transporter activity http://purl.obolibrary.org/obo/GO_0015139 CHEBI:134268 biolink:ChemicalSubstance (S)-mandelamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_134268 chebi_ph7_3 CHEBI:134269 biolink:ChemicalSubstance 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_134269 GO:0015135 biolink:MolecularActivity glucuronate transmembrane transporter activity Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0015135 GO:0015136 biolink:MolecularActivity sialic acid transmembrane transporter activity Enables the transfer of sialic acid from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015136 GO:0015137 biolink:MolecularActivity citrate transmembrane transporter activity Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other. Reactome:R-HSA-433104|TC:2.A.29.7.2 go-plus.json tricarboxylate transport protein http://purl.obolibrary.org/obo/GO_0015137 GO:0015138 biolink:MolecularActivity fumarate transmembrane transporter activity Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate. go-plus.json dicarboxylate (succinate/fumarate/malate) antiporter activity http://purl.obolibrary.org/obo/GO_0015138 GO:0015131 biolink:MolecularActivity oxaloacetate transmembrane transporter activity Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015131 GO:0030772 biolink:MolecularActivity tryptophan 2-C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+). MetaCyc:TRYPTOPHAN-2-C-METHYLTRANSFERASE-RXN|KEGG_REACTION:R08547|EC:2.1.1.106|RHEA:17321 go-plus.json S-adenosylmethionine:tryptophan 2-methyltransferase activity|S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity|tryptophan 2-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030772 GO:0015132 biolink:MolecularActivity prostaglandin transmembrane transporter activity Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. Reactome:R-HSA-5661188|Reactome:R-HSA-879528 go-plus.json prostaglandin/thromboxane transporter activity http://purl.obolibrary.org/obo/GO_0015132 GO:0030773 biolink:MolecularActivity 6-hydroxymellein O-methyltransferase activity Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+). KEGG_REACTION:R03934|EC:2.1.1.108|RHEA:15201|MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN go-plus.json 6-hydroxymellein methyltransferase activity|S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030773 GO:0015133 biolink:MolecularActivity uronic acid transmembrane transporter activity Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose. go-plus.json http://purl.obolibrary.org/obo/GO_0015133 GO:0030770 biolink:MolecularActivity demethylmacrocin O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin. KEGG_REACTION:R02859|MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN|RHEA:17573|EC:2.1.1.102 go-plus.json demethylmacrocin methyltransferase activity|S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030770 GO:0015134 biolink:MolecularActivity hexuronate transmembrane transporter activity Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6. go-plus.json hexuronide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015134 GO:0030771 biolink:MolecularActivity N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+). RHEA:17405|MetaCyc:2.1.1.105-RXN|KEGG_REACTION:R04421|EC:2.1.1.105 go-plus.json S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity|N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity|benzoyl-CoA:anthranilate N-benzoyltransferase http://purl.obolibrary.org/obo/GO_0030771 CHEBI:134262 biolink:ChemicalSubstance L-arginyl-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134262 GO:0015130 biolink:MolecularActivity mevalonate transmembrane transporter activity Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds. go-plus.json monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity http://purl.obolibrary.org/obo/GO_0015130 GO:0030769 biolink:MolecularActivity macrocin O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin. MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN|RHEA:17269|EC:2.1.1.101|KEGG_REACTION:R02858 go-plus.json S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity|S-adenosyl-L-methionine-macrocin O-methyltransferase activity|macrocin methyltransferase activity http://purl.obolibrary.org/obo/GO_0030769 GO:0030767 biolink:MolecularActivity 3-hydroxyanthranilate 4-C-methyltransferase activity Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+). EC:2.1.1.97|KEGG_REACTION:R02667|RHEA:17833|MetaCyc:2.1.1.97-RXN go-plus.json S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity|3-hydroxyanthranilate 4-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030767 GO:0030768 biolink:MolecularActivity 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+). EC:2.1.1.99|RHEA:11336|KEGG_REACTION:R04013|MetaCyc:2.1.1.99-RXN go-plus.json S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity|16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity|NMT activity http://purl.obolibrary.org/obo/GO_0030768 GO:0030765 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030765 GO:0030766 biolink:MolecularActivity 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline. EC:2.1.1.94|RHEA:20992|MetaCyc:2.1.1.94-RXN go-plus.json S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity|S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity|11-demethyl-17-deacetylvindoline 11-methyltransferase activity|tabersonine 16-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030766 GO:0030763 biolink:MolecularActivity isobutyraldoxime O-methyltransferase activity Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+). RHEA:10996|KEGG_REACTION:R04169|EC:2.1.1.91|MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosylmethionine:aldoxime O-methyltransferase activity|aldoxime methyltransferase activity|aldoxime O-methyltransferase activity|S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030763 GO:0030764 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030764 CHEBI:134278 biolink:ChemicalSubstance S-adenosyl-S-carboxymethyl-L-homocysteine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134278 chebi_ph7_3 GO:0015146 biolink:MolecularActivity pentose transmembrane transporter activity Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms. go-plus.json http://purl.obolibrary.org/obo/GO_0015146 GO:0015147 biolink:MolecularActivity L-arabinose transmembrane transporter activity Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc. go-plus.json L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015147 GO:0015148 biolink:MolecularActivity D-xylose transmembrane transporter activity Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides. go-plus.json http://purl.obolibrary.org/obo/GO_0015148 GO:0015149 biolink:MolecularActivity hexose transmembrane transporter activity Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other. Reactome:R-HSA-5638222|Reactome:R-HSA-189242 go-plus.json http://purl.obolibrary.org/obo/GO_0015149 GO:0030761 biolink:MolecularActivity 8-hydroxyquercitin 8-O-methyltransferase activity Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+). KEGG_REACTION:R04398|MetaCyc:2.1.1.88-RXN|RHEA:16593|EC:2.1.1.88 go-plus.json 8-hydroxyquercetin 8-O-methyltransferase activity|flavonol 8-methyltransferase activity|flavonol 8-O-methyltransferase activity|S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030761 GO:0015142 biolink:MolecularActivity tricarboxylic acid transmembrane transporter activity Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups. Reactome:R-HSA-372449|Reactome:R-HSA-75849 go-plus.json sodium:dicarboxylate/tricarboxylate symporter activity http://purl.obolibrary.org/obo/GO_0015142 GO:0030762 biolink:MolecularActivity tetrahydrocolumbamine 2-O-methyltransferase activity Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine. KEGG_REACTION:R04077|MetaCyc:2.1.1.89-RXN|EC:2.1.1.89|RHEA:22536 go-plus.json S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity|tetrahydrocolumbamine methyltransferase activity http://purl.obolibrary.org/obo/GO_0030762 GO:0015143 biolink:MolecularActivity urate transmembrane transporter activity Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. Reactome:R-HSA-2872497|Reactome:R-HSA-5625210|Reactome:R-HSA-561253 go-plus.json uric acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015143 GO:0015144 biolink:MolecularActivity carbohydrate transmembrane transporter activity Enables the transfer of carbohydrate from one side of a membrane to the other. go-plus.json sugar transporter|carbohydrate transporter activity http://purl.obolibrary.org/obo/GO_0015144 GO:0030760 biolink:MolecularActivity pyridine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine. KEGG_REACTION:R02862|Reactome:R-HSA-175987|MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN|RHEA:16893|EC:2.1.1.87 go-plus.json pyridine methyltransferase activity|S-adenosyl-L-methionine:pyridine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030760 GO:0015145 biolink:MolecularActivity monosaccharide transmembrane transporter activity Enables the transfer of a monosaccharide from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015145 CHEBI:134275 biolink:ChemicalSubstance keto-L-tagatose go-plus.json http://purl.obolibrary.org/obo/CHEBI_134275 chebi_ph7_3 GO:0015140 biolink:MolecularActivity malate transmembrane transporter activity Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. go-plus.json dicarboxylate (succinate/fumarate/malate) antiporter activity http://purl.obolibrary.org/obo/GO_0015140 GO:0015141 biolink:MolecularActivity succinate transmembrane transporter activity Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other. go-plus.json dicarboxylate (succinate/fumarate/malate) antiporter activity http://purl.obolibrary.org/obo/GO_0015141 GO:0030758 biolink:MolecularActivity 3,7-dimethylquercitin 4'-O-methyltransferase activity Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+). MetaCyc:2.1.1.83-RXN|RHEA:21832|EC:2.1.1.83|KEGG_REACTION:R03456 go-plus.json S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|flavonol 4'-methyltransferase activity|flavonol 4'-O-methyltransferase activity|4'-OMT activity|3,7-dimethylquercetin 4'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030758 GO:0030759 biolink:MolecularActivity methylquercetagetin 6-O-methyltransferase activity Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+). MetaCyc:2.1.1.84-RXN|KEGG_REACTION:R04505|EC:2.1.1.84|RHEA:18717 go-plus.json flavonol 6-methyltransferase activity|S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity|flavonol 6-O-methyltransferase activity|6-OMT http://purl.obolibrary.org/obo/GO_0030759 GO:0030756 biolink:MolecularActivity isoorientin 3'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin. RHEA:24096|MetaCyc:ISOORIENTIN-3-O-METHYLTRANSFERASE-RXN|EC:2.1.1.78|KEGG_REACTION:R03731 go-plus.json S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity|isoorientin 3'-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030756 GO:0030757 biolink:MolecularActivity 3-methylquercitin 7-O-methyltransferase activity Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine. RHEA:16181|MetaCyc:2.1.1.82-RXN|EC:2.1.1.82|KEGG_REACTION:R05323 go-plus.json flavonol 7-O-methyltransferase activity|S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|7-OMT activity|3-methylquercetin 7-O-methyltransferase activity|flavonol 7-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030757 GO:0005798 biolink:CellularComponent Golgi-associated vesicle Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. NIF_Subcellular:sao819927218 go-plus.json Golgi vesicle|vesicular component http://purl.obolibrary.org/obo/GO_0005798 GO:0030754 biolink:MolecularActivity apigenin 4'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone. RHEA:20429|EC:2.1.1.75|MetaCyc:APIGENIN-4-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity|flavonoid methyltransferase activity|flavonoid O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030754 GO:0030755 biolink:MolecularActivity quercetin 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone. MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN|EC:2.1.1.76|RHEA:17673 go-plus.json flavonol 3-O-methyltransferase activity|flavonoid 3-methyltransferase activity|S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030755 GO:0005799 biolink:CellularComponent obsolete coatomer OBSOLETE. (Was not defined before being made obsolete). go-plus.json COPI vesicle|coatomer http://purl.obolibrary.org/obo/GO_0005799 GO:0030752 biolink:MolecularActivity 5-hydroxyfuranocoumarin 5-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin. RHEA:11808|EC:2.1.1.69|MetaCyc:2.1.1.69-RXN go-plus.json S-adenosyl-L-methionine:bergaptolO-methyltransferase activity|BMT activity|furanocoumarin 5-methyltransferase activity|furanocoumarin 5-O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity|S-adenosyl-L-methionine:bergaptol O-methyltransferase activity|bergaptol methyltransferase activity|bergaptol O-methyltransferase activity|bergaptol 5-O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030752 GO:0005796 biolink:CellularComponent Golgi lumen The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks. go-plus.json http://purl.obolibrary.org/obo/GO_0005796 GO:0030753 biolink:MolecularActivity 8-hydroxyfuranocoumarin 8-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin. EC:2.1.1.70|KEGG_REACTION:R02982 go-plus.json xanthotoxol O-methyltransferase activity|S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity|furanocoumarin 8-O-methyl-transferase activity|xanthotoxol 8-O-methyltransferase activity|XMT activity|S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity|S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity|furanocoumarin 8-methyltransferase activity|xanthotoxol methyltransferase activity http://purl.obolibrary.org/obo/GO_0030753 GO:0005797 biolink:CellularComponent Golgi medial cisterna The middle Golgi cisterna (or cisternae). go-plus.json http://purl.obolibrary.org/obo/GO_0005797 GO:0005794 biolink:CellularComponent Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. NIF_Subcellular:sao451912436|Wikipedia:Golgi_apparatus go-plus.json Golgi complex|Golgi ribbon|Golgi http://purl.obolibrary.org/obo/GO_0005794 goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic GO:0005795 biolink:CellularComponent Golgi stack The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack. go-plus.json dictyosome|Golgi cisternae http://purl.obolibrary.org/obo/GO_0005795 GO:0005792 biolink:CellularComponent obsolete microsome OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g. Wikipedia:Microsome go-plus.json microsomal membrane|microsome http://purl.obolibrary.org/obo/GO_0005792 GO:0005793 biolink:CellularComponent endoplasmic reticulum-Golgi intermediate compartment A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport. Wikipedia:Vesicular-tubular_cluster go-plus.json ERGIC|vesicular-tubular cluster|endoplasmic reticulum-Golgi transport container|EGTC|ER-Golgi transport container|pre-Golgi intermediate compartment|ER-Golgi intermediate compartment|VTC http://purl.obolibrary.org/obo/GO_0005793 GO:0005790 biolink:CellularComponent smooth endoplasmic reticulum The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER. NIF_Subcellular:sao710427438|Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum go-plus.json SER|smooth ER http://purl.obolibrary.org/obo/GO_0005790 GO:0005791 biolink:CellularComponent rough endoplasmic reticulum The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum|NIF_Subcellular:sao1881364067 go-plus.json rough ER|RER http://purl.obolibrary.org/obo/GO_0005791 GO:0015117 biolink:MolecularActivity thiosulfate transmembrane transporter activity Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other. RHEA:32807 go-plus.json thiosulfate permease activity|thiosulphate transporter activity http://purl.obolibrary.org/obo/GO_0015117 CHEBI:134246 biolink:ChemicalSubstance (R)-2-hydroxyglutaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_134246 GO:0015118 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015118 CHEBI:134247 biolink:ChemicalSubstance (11R)-11-hydroperoxylinoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134247 GO:0015119 biolink:MolecularActivity hexose phosphate transmembrane transporter activity Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0015119 GO:0015113 biolink:MolecularActivity nitrite transmembrane transporter activity Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other. go-plus.json nitrite/nitrate porter activity http://purl.obolibrary.org/obo/GO_0015113 GO:0015114 biolink:MolecularActivity phosphate ion transmembrane transporter activity Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other. RHEA:32823 go-plus.json phosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015114 GO:0015115 biolink:MolecularActivity silicate transmembrane transporter activity Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates. go-plus.json http://purl.obolibrary.org/obo/GO_0015115 CHEBI:134248 biolink:ChemicalSubstance (11R)-11-hydroperoxylinoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134248 chebi_ph7_3 GO:0015116 biolink:MolecularActivity sulfate transmembrane transporter activity Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other. Reactome:R-HSA-8875871|Reactome:R-HSA-3560789|Reactome:R-HSA-427555|RHEA:34983 go-plus.json sulphate transporter activity|sulfate permease activity http://purl.obolibrary.org/obo/GO_0015116 CHEBI:134249 biolink:ChemicalSubstance alkanesulfonate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134249 chebi_ph7_3 GO:0030750 biolink:MolecularActivity putrescine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+). MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.53|RHEA:15037|KEGG_REACTION:R01153 go-plus.json putrescine methyltransferase activity|S-adenosyl-L-methionine:putrescine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030750 GO:0015110 biolink:MolecularActivity cyanate transmembrane transporter activity Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015110 GO:0030751 biolink:MolecularActivity licodione 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+). EC:2.1.1.65|KEGG_REACTION:R03623|RHEA:18521|MetaCyc:LICODIONE-2-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030751 GO:0015111 biolink:MolecularActivity iodide transmembrane transporter activity Enables the transfer of iodide ions from one side of a membrane to the other. Reactome:R-HSA-209910|Reactome:R-HSA-5627870|Reactome:R-HSA-5627802 go-plus.json http://purl.obolibrary.org/obo/GO_0015111 NCBITaxon:5297 biolink:OrganismalEntity Puccinia graminis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5297 GO:0015112 biolink:MolecularActivity nitrate transmembrane transporter activity Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. RHEA:34923 go-plus.json nitrite/nitrate porter activity http://purl.obolibrary.org/obo/GO_0015112 NCBITaxon:5296 biolink:OrganismalEntity Puccinia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5296 CHEBI:134243 biolink:ChemicalSubstance phosphatidylethanolamine 40:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134243 CHEBI:134241 biolink:ChemicalSubstance phosphatidylethanolamine 40:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134241 GO:0030747 biolink:MolecularActivity indolepyruvate C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate. EC:2.1.1.47|MetaCyc:INDOLEPYRUVATE-C-METHYLTRANSFERASE-RXN|RHEA:12112 go-plus.json S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity|indolepyruvate methyltransferase activity|indolepyruvate 3-methyltransferase activity|indolepyruvic acid methyltransferase activity|S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030747 GO:0030748 biolink:MolecularActivity amine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine. MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.49 go-plus.json arylamine N-methyltransferase activity|nicotine N-methyltransferase activity|tryptamine N-methyltransferase activity|S-adenosyl-L-methionine:amine N-methyltransferase activity|tryptamine methyltransferase http://purl.obolibrary.org/obo/GO_0030748 GO:0030745 biolink:MolecularActivity dimethylhistidine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine. EC:2.1.1.44|KEGG_REACTION:R04436|RHEA:11104|MetaCyc:2.1.1.44-RXN go-plus.json S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|histidine-alpha-N-methyltransferase activity|dimethylhistidine methyltransferase activity|S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030745 GO:0030746 biolink:MolecularActivity isoflavone 4'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone. EC:2.1.1.46|MetaCyc:ISOFLAVONE-4-O-METHYLTRANSFERASE-RXN|RHEA:31739 go-plus.json 4'-hydroxyisoflavone methyltransferase activity|S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity|isoflavone methyltransferase activity|isoflavone O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030746 GO:0030743 biolink:MolecularActivity rRNA (adenosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine. RHEA:43212|MetaCyc:2.1.1.66-RXN|EC:2.1.1.230 go-plus.json S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity|ribosomal ribonucleate adenosine 2'-methyltransferase activity|rRNA adenosine 2'-methylase activity|thiostrepton-resistance methylase activity|RNA-pentose methylase activity http://purl.obolibrary.org/obo/GO_0030743 GO:0030744 biolink:MolecularActivity luteolin O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+). EC:2.1.1.42|RHEA:14589|KEGG_REACTION:R03587|MetaCyc:LUTEOLIN-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity|S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity|o-dihydric phenol meta-O-methyltransferase activity|luteolin methyltransferase activity|o-dihydric phenol methyltransferase activity|o-diphenol m-O-methyltransferase activity|luteolin 3'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030744 GO:0030741 biolink:MolecularActivity inositol 1-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). EC:2.1.1.40|MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01188|RHEA:17565 go-plus.json inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity|inositol 3-O-methyltransferase activity|S-adenosylmethionine:myo-inositol 3-methyltransferase activity|myo-inositol 3-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity|inositol D-1-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030741 GO:0030742 biolink:MolecularActivity GTP-dependent protein binding Binding to a protein or protein complex when at least one of the interacting partners is in the GTP-bound state. go-plus.json http://purl.obolibrary.org/obo/GO_0030742 GO:0030749 biolink:MolecularActivity loganate O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin. RHEA:12508|EC:2.1.1.50|MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity|S-adenosyl-L-methionine:loganic acid methyltransferase activity|loganate methyltransferase activity http://purl.obolibrary.org/obo/GO_0030749 CHEBI:134257 biolink:ChemicalSubstance lipid A(4-) (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134257 chebi_ph7_3 GO:0015128 biolink:MolecularActivity gluconate transmembrane transporter activity Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose. go-plus.json L-idonate/D-gluconate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015128 GO:0015129 biolink:MolecularActivity lactate transmembrane transporter activity Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. Reactome:R-HSA-373867|Reactome:R-HSA-373875 go-plus.json monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity http://purl.obolibrary.org/obo/GO_0015129 CHEBI:134258 biolink:ChemicalSubstance beta-L-Ara4N-lipid A (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134258 CHEBI:134256 biolink:ChemicalSubstance lipid A (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134256 GO:0015124 biolink:MolecularActivity allantoate transmembrane transporter activity Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0015124 GO:0015125 biolink:MolecularActivity bile acid transmembrane transporter activity Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. Reactome:R-HSA-194130|Reactome:R-HSA-5661198|Reactome:R-HSA-194079|Reactome:R-HSA-194083|Reactome:R-HSA-5661184 go-plus.json http://purl.obolibrary.org/obo/GO_0015125 GO:0015126 biolink:MolecularActivity canalicular bile acid transmembrane transporter activity The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. go-plus.json http://purl.obolibrary.org/obo/GO_0015126 CHEBI:134259 biolink:ChemicalSubstance beta-L-Ara4N-lipid A(2-) (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134259 chebi_ph7_3 GO:0015127 biolink:MolecularActivity bilirubin transmembrane transporter activity Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile. Reactome:R-HSA-5679041|Reactome:R-HSA-9661417|Reactome:R-HSA-5679031 go-plus.json http://purl.obolibrary.org/obo/GO_0015127 GO:0015120 biolink:MolecularActivity phosphoglycerate transmembrane transporter activity Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0015120 GO:0015121 biolink:MolecularActivity phosphoenolpyruvate:phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out). go-plus.json phosphoenolpyruvate/phosphate translocator|PPT http://purl.obolibrary.org/obo/GO_0015121 GO:0030740 biolink:MolecularActivity inositol 3-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). KEGG_REACTION:R01189|MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN|RHEA:18877|EC:2.1.1.39 go-plus.json inositol L-1-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity|S-adenosylmethionine:myo-inositol 1-methyltransferase activity|myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|myo-inositol 1-methyltransferase activity|myo-inositol 1-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030740 GO:0015122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015122 GO:0015123 biolink:MolecularActivity acetate transmembrane transporter activity Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0015123 CHEBI:134251 biolink:ChemicalSubstance guaiacols go-plus.json http://purl.obolibrary.org/obo/CHEBI_134251 chebi_ph7_3 GO:0030736 biolink:MolecularActivity phenol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+). RHEA:14809|EC:2.1.1.25|KEGG_REACTION:R01239|MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:phenol O-methyltransferase activity|PMT http://purl.obolibrary.org/obo/GO_0030736 PO:0000045 biolink:OntologyClass embryo root A root (PO:0009005) that is initiated in a developing plant embryo (PO:0009009). go-plus.json embryonic root (exact)|初期の根、胚根 (Japanese, exact)|raíz embriónica (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000045 GO:0030737 biolink:MolecularActivity iodophenol O-methyltransferase activity Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+). MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.26|KEGG_REACTION:R03746|RHEA:14313 go-plus.json S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030737 GO:0005778 biolink:CellularComponent peroxisomal membrane The lipid bilayer surrounding a peroxisome. go-plus.json peroxisome membrane http://purl.obolibrary.org/obo/GO_0005778 GO:0030734 biolink:MolecularActivity polysaccharide O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units. EC:2.1.1.18|MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity|polysaccharide methyltransferase activity|acylpolysacharide 6-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030734 GO:0030735 biolink:MolecularActivity carnosine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+). Reactome:R-HSA-8876789|EC:2.1.1.22|RHEA:14205|KEGG_REACTION:R02144|MetaCyc:CARNOSINE-N-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:carnosine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030735 GO:0005779 biolink:CellularComponent integral component of peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to peroxisomal membrane http://purl.obolibrary.org/obo/GO_0005779 GO:0030732 biolink:MolecularActivity methionine S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine. EC:2.1.1.12|MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN|RHEA:13761 go-plus.json S-adenosylmethionine transmethylase activity|methionine methyltransferase activity|S-adenosyl methionine:methionine methyl transferase activity|S-adenosylmethionine-methionine methyltransferase activity|S-adenosyl-L-methionine:L-methionine S-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030732 GO:0005776 biolink:CellularComponent autophagosome A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy. NIF_Subcellular:sao8663416959 go-plus.json autophagic vacuole|initial autophagic vacuole http://purl.obolibrary.org/obo/GO_0005776 GO:0030733 biolink:MolecularActivity fatty acid O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester. MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN|EC:2.1.1.15|RHEA:23012 go-plus.json fatty acid methyltransferase activity|fatty-acid O-methyltransferase activity|S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030733 GO:0005777 biolink:CellularComponent peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. Wikipedia:Peroxisome|NIF_Subcellular:sao499555322 go-plus.json peroxisomal|peroxisome vesicle http://purl.obolibrary.org/obo/GO_0005777 goslim_chembl|goslim_candida|goslim_yeast|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic GO:0030730 biolink:BiologicalProcess sequestering of triglyceride The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. go-plus.json triglyceride sequestering|triglyceride retention|sequestration of triglyceride|triglyceride storage|sequestration of triacylglycerol|triacylglycerol retention|triglyceride sequestration|storage of triacylglycerol|triacylglycerol storage|retention of triacylglycerol|triacylglycerol sequestration|triacylglycerol sequestering|sequestering of triacylglycerol|retention of triglyceride|storage of triglyceride http://purl.obolibrary.org/obo/GO_0030730 GO:0005774 biolink:CellularComponent vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0005774 GO:0030731 biolink:MolecularActivity guanidinoacetate N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+). EC:2.1.1.2|MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN|RHEA:10656|KEGG_REACTION:R01883 go-plus.json guanidinoacetate methyltransferase activity|methionine-guanidinoacetic transmethylase activity|S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity|guanidinoacetate transmethylase activity|GA methylpherase activity|guanidoacetate methyltransferase activity http://purl.obolibrary.org/obo/GO_0030731 GO:0005775 biolink:CellularComponent vacuolar lumen The volume enclosed within the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0005775 GO:0005772 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005772 GO:0005773 biolink:CellularComponent vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. Wikipedia:Vacuole go-plus.json vacuolar carboxypeptidase Y http://purl.obolibrary.org/obo/GO_0005773 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic GO:0005770 biolink:CellularComponent late endosome A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. NIF_Subcellular:nlx_subcell_20090702 go-plus.json PVC|prevacuolar compartment http://purl.obolibrary.org/obo/GO_0005770 GO:0005771 biolink:CellularComponent multivesicular body A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. NIF_Subcellular:sao2045955158 go-plus.json MVB|MVE|multivesicular endosome http://purl.obolibrary.org/obo/GO_0005771 GO:0030738 biolink:MolecularActivity tyramine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+). KEGG_REACTION:R02384|EC:2.1.1.27|MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN|RHEA:14865 go-plus.json DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)|S-adenosyl-L-methionine:tyramine N-methyltransferase activity|tyramine methylpherase activity|S-adenosyl-methionine:tyramine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030738 GO:0030739 biolink:MolecularActivity O-demethylpuromycin O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin. MetaCyc:2.1.1.38-RXN|RHEA:22280|EC:2.1.1.38 go-plus.json S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity|O-demethylpuromycin methyltransferase activity http://purl.obolibrary.org/obo/GO_0030739 CHEBI:134225 biolink:ChemicalSubstance 1,4-benzosemiquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_134225 chebi_ph7_3 CHEBI:6618 biolink:ChemicalSubstance MET-enkephalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6618 PO:0000033 biolink:OntologyClass fruit valve A valve that is a part of a fruit that splits apart when the fruit dehisces. go-plus.json 果実の弁 (Japanese, exact)|valva de fruto (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000033 GO:0030725 biolink:BiologicalProcess germline ring canal formation Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts. go-plus.json ring canal formation http://purl.obolibrary.org/obo/GO_0030725 GO:0030726 biolink:BiologicalProcess male germline ring canal formation Formation of the intercellular bridges that connect the germ-line cells of a male cyst. go-plus.json testicular ring canal formation|spermatocyte ring canal formation http://purl.obolibrary.org/obo/GO_0030726 GO:0030723 biolink:BiologicalProcess ovarian fusome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions. go-plus.json ovarian fusome organisation|ovarian fusome organization and biogenesis http://purl.obolibrary.org/obo/GO_0030723 GO:0005789 biolink:CellularComponent endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum. go-plus.json ER membrane http://purl.obolibrary.org/obo/GO_0005789 GO:0030724 biolink:BiologicalProcess testicular fusome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome. go-plus.json testicular fusome organisation|testicular fusome organization and biogenesis http://purl.obolibrary.org/obo/GO_0030724 GO:0030721 biolink:BiologicalProcess spectrosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome. go-plus.json spectrosome organization and biogenesis|spectrosome organisation http://purl.obolibrary.org/obo/GO_0030721 CHEBI:148869 biolink:ChemicalSubstance alpha-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_148869 GO:0005787 biolink:CellularComponent signal peptidase complex A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space. go-plus.json http://purl.obolibrary.org/obo/GO_0005787 PO:0000037 biolink:OntologyClass shoot axis apex A shoot axis (PO:0025029) that is the most distal part of a shoot system (PO:0009006) and has as parts a shoot apical meristem (PO:0020148) and the youngest primordia (PO:0025127). go-plus.json ápice del epiblasto (epiblastema) (Spanish, exact)|シュート頂、茎頂 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000037 PO:0000038 biolink:OntologyClass primary endosperm cell Cell produced by the fusion of sperm cell nucleus and two polar nuclei of the central cell (or diploid secondary endosperm nucleus, in cases where two polar nuclei fuse together before double fertilization). The first cell of the endosperm, often triploid. go-plus.json célula primaria del endosperma (Spanish, exact)|一次胚乳細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000038 GO:0005788 biolink:CellularComponent endoplasmic reticulum lumen The volume enclosed by the membranes of the endoplasmic reticulum. go-plus.json ER cisterna|ER lumen|endoplasmic reticulum cisterna|cisternal lumen http://purl.obolibrary.org/obo/GO_0005788 GO:0030722 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030722 GO:0005785 biolink:CellularComponent signal recognition particle receptor complex A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex. go-plus.json docking protein complex|SR complex http://purl.obolibrary.org/obo/GO_0005785 GO:0030720 biolink:BiologicalProcess oocyte localization involved in germarium-derived egg chamber formation Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. go-plus.json oogenesis, oocyte localization|oocyte localization during oogenesis|establishment and maintenance of oocyte position during oogenesis|oocyte localization during germarium-derived egg chamber formation|oocyte localisation involved in germarium-derived egg chamber formation|oocyte positioning during oogenesis|oogenesis, establishment and maintenance of oocyte localization|establishment and maintenance of oocyte localization in egg chamber http://purl.obolibrary.org/obo/GO_0030720 GO:0005786 biolink:CellularComponent signal recognition particle, endoplasmic reticulum targeting A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana. Wikipedia:Signal_recognition_particle go-plus.json signal sequence receptor complex|SRP http://purl.obolibrary.org/obo/GO_0005786 GO:0005783 biolink:CellularComponent endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). NIF_Subcellular:sao1036339110|Wikipedia:Endoplasmic_reticulum go-plus.json ER http://purl.obolibrary.org/obo/GO_0005783 goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr GO:0005784 biolink:CellularComponent Sec61 translocon complex A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events. go-plus.json Sec61p-Sbh1p-Sss1p complex http://purl.obolibrary.org/obo/GO_0005784 GO:0005781 biolink:CellularComponent obsolete peroxisome targeting signal receptor complex OBSOLETE. (Was not defined before being made obsolete). go-plus.json peroxisome targeting signal receptor complex http://purl.obolibrary.org/obo/GO_0005781 GO:0005782 biolink:CellularComponent peroxisomal matrix The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase. go-plus.json peroxisomal lumen http://purl.obolibrary.org/obo/GO_0005782 GO:0030729 biolink:MolecularActivity acetoacetate-CoA ligase activity Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+). Reactome:R-HSA-5694494|EC:6.2.1.16|MetaCyc:ACETOACETATE--COA-LIGASE-RXN|KEGG_REACTION:R01357|RHEA:16117 go-plus.json acetoacetyl-CoA synthetase activity|acetoacetate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0030729 GO:0005780 biolink:CellularComponent extrinsic component of intraperoxisomal membrane The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json intra-peroxisomal peripheral membrane|extrinsic to intraperoxisomal membrane http://purl.obolibrary.org/obo/GO_0005780 GO:0030727 biolink:BiologicalProcess germarium-derived female germ-line cyst formation Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster. go-plus.json germarium-derived female germline cyst formation http://purl.obolibrary.org/obo/GO_0030727 GO:0030728 biolink:BiologicalProcess ovulation The release of a mature ovum/oocyte from an ovary. Wikipedia:Ovulation go-plus.json http://purl.obolibrary.org/obo/GO_0030728 GO:0015106 biolink:MolecularActivity bicarbonate transmembrane transporter activity Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. Reactome:R-HSA-2752067|RHEA:28695 go-plus.json http://purl.obolibrary.org/obo/GO_0015106 GO:0015107 biolink:MolecularActivity chlorate transmembrane transporter activity Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015107 CHEBI:134236 biolink:ChemicalSubstance phosphatidic acid (16:0/18:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134236 GO:0015108 biolink:MolecularActivity chloride transmembrane transporter activity Enables the transfer of chloride ions from one side of a membrane to the other. MetaCyc:3.6.3.11-RXN|Reactome:R-HSA-5678822|Reactome:R-HSA-5678992|RHEA:29823|Reactome:R-HSA-5678863 go-plus.json chloride ABC transporter|chloride transporting ATPase activity|ATP-dependent chloride transmembrane transporter activity|ATPase-coupled chloride transmembrane transporter activity|chloride ion transmembrane transporter activity|chloride-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015108 CHEBI:134233 biolink:ChemicalSubstance (4S)-4,16-dihydroxyretinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134233 chebi_ph7_3 GO:0015109 biolink:MolecularActivity chromate transmembrane transporter activity Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3. RHEA:32819 go-plus.json http://purl.obolibrary.org/obo/GO_0015109 GO:0015103 biolink:MolecularActivity inorganic anion transmembrane transporter activity Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0015103 GO:0015104 biolink:MolecularActivity antimonite transmembrane transporter activity Enables the transfer of antimonite from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015104 CHEBI:134237 biolink:ChemicalSubstance phosphatidic acid 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134237 GO:0015105 biolink:MolecularActivity arsenite transmembrane transporter activity Enables the transfer of arsenite from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015105 GO:0015100 biolink:MolecularActivity vanadium ion transmembrane transporter activity Enables the transfer of vanadium (V) ions from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015100 GO:0015101 biolink:MolecularActivity organic cation transmembrane transporter activity Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage. Reactome:R-HSA-561072|Reactome:R-HSA-549304|Reactome:R-HSA-549322|Reactome:R-HSA-561054|Reactome:R-HSA-549279|Reactome:R-HSA-2161500|Reactome:R-HSA-549129 go-plus.json http://purl.obolibrary.org/obo/GO_0015101 PO:0000042 biolink:OntologyClass shoot-borne root A root (PO:0009005) that develops from shoot axis (PO:0025029) tissue. go-plus.json climbing root (broad)|stilt root (narrow)|シュート細胞由来の根 (Japanese, exact)|aerial root (narrow)|epiblasto (epiblastema) que se origina en la raíz (Spanish, exact)|adventitious root (broad) http://purl.obolibrary.org/obo/PO_0000042 GO:0030714 biolink:BiologicalProcess anterior/posterior axis specification, follicular epithelium Polarization of the follicle cells of an insect ovary along the anterior/posterior axis. go-plus.json anterior/posterior axis determination, follicular epithelium http://purl.obolibrary.org/obo/GO_0030714 GO:0005758 biolink:CellularComponent mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope. NIF_Subcellular:sao118944228 go-plus.json mitochondrial envelope lumen|mitochondrial membrane lumen http://purl.obolibrary.org/obo/GO_0005758 GO:0005759 biolink:CellularComponent mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. Wikipedia:Mitochondrial_matrix|NIF_Subcellular:sao1804523077 go-plus.json mitochondrial lumen|mitochondrial stroma http://purl.obolibrary.org/obo/GO_0005759 GO:0030715 biolink:BiologicalProcess oocyte growth in germarium-derived egg chamber The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0030715 GO:0030712 biolink:BiologicalProcess negative regulation of border follicle cell delamination Any process that decreases the frequency, rate or extent of border cell delamination. go-plus.json down-regulation of border follicle cell delamination|inhibition of border follicle cell delamination|negative regulation of border cell delamination|down regulation of border follicle cell delamination|downregulation of border follicle cell delamination http://purl.obolibrary.org/obo/GO_0030712 GO:0005756 biolink:CellularComponent mitochondrial proton-transporting ATP synthase, central stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis. go-plus.json http://purl.obolibrary.org/obo/GO_0005756 GO:0005757 biolink:CellularComponent mitochondrial permeability transition pore complex A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). go-plus.json PTPC|MPTP complex|mitochondrial PT pore complex http://purl.obolibrary.org/obo/GO_0005757 PO:0000025 biolink:OntologyClass root tip A cardinal organ part (PO:0025001) which is the apical portion of the root (PO:0009005), and includes the root apical meristem (PO:0020147) and root cap (PO:0020123). go-plus.json 根端 (Japanese, exact)|punta de la raíz (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000025 GO:0030713 biolink:BiologicalProcess ovarian follicle cell stalk formation Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0030713 GO:0030710 biolink:BiologicalProcess regulation of border follicle cell delamination Any process that regulates the frequency, rate or extent of border cell delamination. go-plus.json regulation of border cell delamination http://purl.obolibrary.org/obo/GO_0030710 GO:0005754 biolink:CellularComponent mitochondrial proton-transporting ATP synthase, catalytic core The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase. go-plus.json http://purl.obolibrary.org/obo/GO_0005754 GO:0005755 biolink:CellularComponent obsolete hydrogen-transporting ATP synthase, coupling factor CF(0) OBSOLETE. (Was not defined before being made obsolete). go-plus.json hydrogen-transporting ATP synthase, coupling factor CF(0) http://purl.obolibrary.org/obo/GO_0005755 GO:0030711 biolink:BiologicalProcess positive regulation of border follicle cell delamination Any process that increases the frequency, rate or extent of border cell delamination. go-plus.json up-regulation of border follicle cell delamination|upregulation of border follicle cell delamination|positive regulation of border cell delamination|up regulation of border follicle cell delamination|activation of border follicle cell delamination|stimulation of border follicle cell delamination http://purl.obolibrary.org/obo/GO_0030711 GO:0005752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005752 GO:0005753 biolink:CellularComponent mitochondrial proton-transporting ATP synthase complex A proton-transporting ATP synthase complex found in the mitochondrial membrane. go-plus.json mitochondrial respiratory chain complex V http://purl.obolibrary.org/obo/GO_0005753 GO:0005750 biolink:CellularComponent mitochondrial respiratory chain complex III A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. go-plus.json mitochondrial coenzyme Q-cytochrome c oxidoreductase complex|mitochondrial ubiquinol-cytochrome c oxidoreductase complex|mitochondrial electron transport complex III|mitochondrial coenzyme Q-cytochrome c reductase complex|mitochondrial ubiquinol-cytochrome-c reductase complex|mitochondrial cytochrome bc(1) complex|mitochondrial complex III|mitochondrial cytochrome bc1 complex http://purl.obolibrary.org/obo/GO_0005750 GO:0005751 biolink:CellularComponent mitochondrial respiratory chain complex IV A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). go-plus.json http://purl.obolibrary.org/obo/GO_0005751 CHEBI:134208 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-L-tyrosyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_134208 chebi_ph7_3 CHEBI:134209 biolink:ChemicalSubstance aporphine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134209 GO:0030718 biolink:BiologicalProcess germ-line stem cell population maintenance Any process by which an organism or tissue maintains a population of germ-line stem cells. go-plus.json http://purl.obolibrary.org/obo/GO_0030718 GO:0030719 biolink:BiologicalProcess P granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes. go-plus.json polar granule organisation|P granule organization and biogenesis|polar granule organization and biogenesis http://purl.obolibrary.org/obo/GO_0030719 GO:0030716 biolink:BiologicalProcess oocyte fate determination The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json oocyte cell fate determination http://purl.obolibrary.org/obo/GO_0030716 GO:0030717 biolink:BiologicalProcess oocyte karyosome formation The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. go-plus.json http://purl.obolibrary.org/obo/GO_0030717 CHEBI:134206 biolink:ChemicalSubstance 2-methylserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134206 CHEBI:134207 biolink:ChemicalSubstance methylcytosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134207 CHEBI:134205 biolink:ChemicalSubstance 2-methyl-D-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134205 PO:0000030 biolink:OntologyClass septum A collective organ part structure composed of two or more layers of various tissues that is a partition that divides a cavity formed by the fusion of two or more organs. go-plus.json septa (exact, plural)|隔壁 (Japanese, exact)|dissepiment (broad)|septo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000030 GO:0005769 biolink:CellularComponent early endosome A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. NIF_Subcellular:nlx_subcell_20090701 go-plus.json http://purl.obolibrary.org/obo/GO_0005769 GO:0030703 biolink:BiologicalProcess eggshell formation Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration. go-plus.json http://purl.obolibrary.org/obo/GO_0030703 GO:0030704 biolink:BiologicalProcess vitelline membrane formation Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg. go-plus.json http://purl.obolibrary.org/obo/GO_0030704 GO:0030701 biolink:MolecularActivity NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]. EC:2.4.2.37|MetaCyc:2.4.2.37-RXN|RHEA:18077 go-plus.json NAD--azoferredoxin (ADP-ribose)transferase activity|NAD-azoferredoxin (ADPribose)transferase activity|NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity|NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity|ADP-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0030701 GO:0005767 biolink:CellularComponent secondary lysosome Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome. NIF_Subcellular:sao1549842807 go-plus.json http://purl.obolibrary.org/obo/GO_0005767 GO:0005768 biolink:CellularComponent endosome A vacuole to which materials ingested by endocytosis are delivered. Wikipedia:Endosome|NIF_Subcellular:sao1720343330 go-plus.json http://purl.obolibrary.org/obo/GO_0005768 goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_generic|goslim_chembl|goslim_mouse GO:0030702 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030702 PO:0000015 biolink:OntologyClass cotyledon primordium A phyllome primordium (PO:0025128) that develops from a cotyledon anlagen (PO:0025432) and is part of a vegetative shoot apex (PO:0025223) and is committed to the development of a cotyledon (PO:0020030). go-plus.json primordio de cotiledón (Spanish, exact)|cotyledon primordia (exact, plural)|portion of cotyledon primordium tissue (exact)|子葉原基（可視的）(Japanese, exact) http://purl.obolibrary.org/obo/PO_0000015 GO:0005765 biolink:CellularComponent lysosomal membrane The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. go-plus.json lysosome membrane http://purl.obolibrary.org/obo/GO_0005765 PO:0000016 biolink:OntologyClass lateral root primordium A root primordium (PO:0005029) that is part of a root (PO:0009005) and is committed to the development of a lateral root (PO:0020121). go-plus.json portion of lateral root primordium tissue (exact)|primordio de raíz lateral (Spanish, exact)|側根原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000016 GO:0030700 biolink:CellularComponent glycine reductase complex Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C. go-plus.json http://purl.obolibrary.org/obo/GO_0030700 GO:0005766 biolink:CellularComponent primary lysosome A lysosome before it has fused with a vesicle or vacuole. NIF_Subcellular:sao1140587416 go-plus.json http://purl.obolibrary.org/obo/GO_0005766 GO:0005763 biolink:CellularComponent mitochondrial small ribosomal subunit The smaller of the two subunits of a mitochondrial ribosome. go-plus.json mitochondrial ribosomal SSU complex|mitochondrial ribosomal small subunit complex|28S ribosomal subunit, mitochondrial http://purl.obolibrary.org/obo/GO_0005763 PO:0000017 biolink:OntologyClass vascular leaf primordium A phyllome primordium (PO:0025128) that develops from a vascular leaf anlagen (PO:0025431) and is part of a vegetative shoot apex (PO:0025223) and is committed to the development of a vascular leaf (PO:0009025). go-plus.json primordio de hoja (Spanish, exact)|vascular leaf primordia (exact, plural)|portion of vascular leaf primordium tissue (exact)|葉原基 (Japanese, exact)|leaf primordium (exact) http://purl.obolibrary.org/obo/PO_0000017 GO:0005764 biolink:CellularComponent lysosome A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. Wikipedia:Lysosome|NIF_Subcellular:sao585356902 go-plus.json http://purl.obolibrary.org/obo/GO_0005764 goslim_plant|goslim_generic|goslim_chembl PO:0000018 biolink:OntologyClass ovule primordium A floral structure primordium (PO:0025477) that is committed to the development of an ovule (PO:0020003). go-plus.json 胚珠原基（可視的） (Japanese, exact)|portion of ovule primordium tissue (exact)|primordio de óvulo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000018 PO:0000019 biolink:OntologyClass gynoecium primordium A floral structure primordium (PO:0025477) that is committed to the development of a gynoecium (PO:0009062). go-plus.json 雌蕊原基(可視的） (Japanese, exact)|portion of gynoecium primordium tissue (exact)|pistil primordium (exact)|primordio de gineceo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0000019 GO:0005761 biolink:CellularComponent mitochondrial ribosome A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. go-plus.json 55S ribosome, mitochondrial http://purl.obolibrary.org/obo/GO_0005761 GO:0005762 biolink:CellularComponent mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). go-plus.json 39S ribosomal subunit, mitochondrial http://purl.obolibrary.org/obo/GO_0005762 GO:0030709 biolink:BiologicalProcess border follicle cell delamination The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration. go-plus.json border cell delamination http://purl.obolibrary.org/obo/GO_0030709 CHEBI:134219 biolink:ChemicalSubstance decenals go-plus.json http://purl.obolibrary.org/obo/CHEBI_134219 GO:0005760 biolink:CellularComponent gamma DNA polymerase complex A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0005760 GO:0030707 biolink:BiologicalProcess ovarian follicle cell development The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0030707 GO:0030708 biolink:BiologicalProcess germarium-derived female germ-line cyst encapsulation Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0030708 CHEBI:42485 biolink:ChemicalSubstance formyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_42485 chebi_ph7_3 GO:0030705 biolink:BiologicalProcess cytoskeleton-dependent intracellular transport The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030705 goslim_generic|goslim_chembl|goslim_drosophila GO:0030706 biolink:BiologicalProcess germarium-derived oocyte differentiation The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster. go-plus.json oocyte cell differentiation http://purl.obolibrary.org/obo/GO_0030706 CHEBI:134213 biolink:ChemicalSubstance (S)-1,2,9,10-tetramethoxy-6-methylaporphine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134213 chebi_ph7_3 CHEBI:134214 biolink:ChemicalSubstance L-xylo-3-hexulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_134214 chebi_ph7_3 CHEBI:134211 biolink:ChemicalSubstance (R)-tetrahydropapaverine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134211 chebi_ph7_3 CHEBI:134212 biolink:ChemicalSubstance (S)-glaucine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134212 chebi_ph7_3 CHEBI:134217 biolink:ChemicalSubstance N-methylbulbocapnine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134217 chebi_ph7_3 CHEBI:134215 biolink:ChemicalSubstance bulbocapnine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134215 chebi_ph7_3 CHEBI:134216 biolink:ChemicalSubstance muricholic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_134216 CHEBI:134210 biolink:ChemicalSubstance (R)-laudanosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134210 chebi_ph7_3 PO:0000021 biolink:OntologyClass petal primordium A phyllome primordium (PO:0025128) that develops from a petal anlagen (PO:0025484) and is committed to the development of a petal (PO:0009032). go-plus.json petal primordia (exact, plural)|primordio de pétalo (Spanish, exact)|portion of petal primordium tissue (exact)|花弁原基（可視的） (Japanese, exact) http://purl.obolibrary.org/obo/PO_0000021 CHEBI:437678 biolink:ChemicalSubstance (S)-columbianetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_437678 chebi_ph7_3 UBERON:0019293 biolink:AnatomicalEntity white matter of pontine tegmentum go-plus.json predominantly white regional part of pontine tegmentum|white matter of pontile tegmentum|white substance of pontile tegmentum|substantia alba tegmenti pontis|pontine white matter tracts http://purl.obolibrary.org/obo/UBERON_0019293 UBERON:0019294 biolink:AnatomicalEntity commissure of telencephalon go-plus.json telencephalic commissures http://purl.obolibrary.org/obo/UBERON_0019294 UBERON:0019291 biolink:AnatomicalEntity white matter of metencephalon go-plus.json http://purl.obolibrary.org/obo/UBERON_0019291 UBERON:0019292 biolink:AnatomicalEntity white matter of pons go-plus.json http://purl.obolibrary.org/obo/UBERON_0019292 CHEBI:6457 biolink:ChemicalSubstance lignin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6457 GO:0015296 biolink:MolecularActivity anion:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015296 GO:0015297 biolink:MolecularActivity antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). Reactome:R-HSA-2731002|Reactome:R-HSA-2730959|Reactome:R-HSA-2730692 go-plus.json ion antiporter activity|exchanger|solute:solute exchange|porter|antiport|solute:solute antiporter activity|exchange transporter activity|countertransporter activity http://purl.obolibrary.org/obo/GO_0015297 GO:0015298 biolink:MolecularActivity solute:cation antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015298 GO:0015299 biolink:MolecularActivity solute:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out). Reactome:R-HSA-597628|Reactome:R-HSA-5625574|Reactome:R-HSA-434650 go-plus.json solute:hydrogen antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015299 GO:0015292 biolink:MolecularActivity uniporter activity Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species. go-plus.json uniport|facilitated diffusion carrier|single-species transporter activity http://purl.obolibrary.org/obo/GO_0015292 GO:0015293 biolink:MolecularActivity symporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. go-plus.json symport|cotransporter activity|porter activity http://purl.obolibrary.org/obo/GO_0015293 GO:0015294 biolink:MolecularActivity solute:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015294 GO:0015295 biolink:MolecularActivity solute:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in). go-plus.json proline/glycine/betaine:hydrogen/sodium symporter activity|L-idonate/D-gluconate:hydrogen symporter activity|low affinity metal ion uptake transporter activity|heavy metal ion:hydrogen symporter activity|solute:hydrogen symporter activity|high affinity metal ion uptake transporter activity http://purl.obolibrary.org/obo/GO_0015295 NCBITaxon:40410 biolink:OrganismalEntity Cryptococcus neoformans var. neoformans go-plus.json Filobasidiella neoformans var. neoformans|Cryptococcus neoformans serotype D|Cryptococcus deneoformans http://purl.obolibrary.org/obo/NCBITaxon_40410 GO:0015280 biolink:MolecularActivity ligand-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. Reactome:R-HSA-2672334 go-plus.json acid-sensing ion channel activity|ASIC activity|epithelial sodium channel|amiloride-sensitive sodium channel activity http://purl.obolibrary.org/obo/GO_0015280 GO:0015278 biolink:MolecularActivity calcium-release channel activity Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts. go-plus.json intracellular ligand-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0015278 GO:0015279 biolink:MolecularActivity store-operated calcium channel activity A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores. Reactome:R-HSA-434798 go-plus.json http://purl.obolibrary.org/obo/GO_0015279 GO:0015274 biolink:MolecularActivity organellar voltage-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane. go-plus.json organellar voltage gated chloride channel activity|organellar voltage-dependent chloride channel activity http://purl.obolibrary.org/obo/GO_0015274 GO:0015275 biolink:MolecularActivity stretch-activated, cation-selective, calcium channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching. go-plus.json http://purl.obolibrary.org/obo/GO_0015275 GO:0015276 biolink:MolecularActivity ligand-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. Reactome:R-HSA-622326|Reactome:R-HSA-451311|Reactome:R-HSA-451310|Reactome:R-HSA-629595|Reactome:R-HSA-622325 go-plus.json ionotropic receptor activity http://purl.obolibrary.org/obo/GO_0015276 GO:0015277 biolink:MolecularActivity kainate selective glutamate receptor activity An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist. go-plus.json http://purl.obolibrary.org/obo/GO_0015277 GO:0015270 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015270 GO:0015271 biolink:MolecularActivity outward rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force. go-plus.json http://purl.obolibrary.org/obo/GO_0015271 GO:0015272 biolink:MolecularActivity ATP-activated inward rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. Reactome:R-HSA-5683209 go-plus.json http://purl.obolibrary.org/obo/GO_0015272 GO:0015273 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015273 GO:0015290 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015290 GO:0015291 biolink:MolecularActivity secondary active transmembrane transporter activity Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters. Reactome:R-HSA-199216|TC:2.A go-plus.json secondary carrier-type facilitators|ion-gradient-driven energizer activity|galactose/glucose (methylgalactoside) porter activity|porters|electrochemical potential-driven transporter activity|multidrug endosomal transmembrane transporter activity|porter activity|coupled carrier|heavy metal ion porter activity|energizer of outer membrane receptor-mediated transport activity|nitrite/nitrate porter activity|active transporter http://purl.obolibrary.org/obo/GO_0015291 GO:0015289 biolink:MolecularActivity obsolete pore-forming toxin activity OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell. go-plus.json pore-forming toxin activity http://purl.obolibrary.org/obo/GO_0015289 GO:0015285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015285 GO:0015286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015286 GO:0015287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015287 GO:0015288 biolink:MolecularActivity porin activity Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. Wikipedia:Porin_(protein) go-plus.json porin|outer membrane exporter porin http://purl.obolibrary.org/obo/GO_0015288 CHEBI:6444 biolink:ChemicalSubstance Levorphanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_6444 GO:0015281 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015281 GO:0015282 biolink:MolecularActivity obsolete NADPH oxidase-associated cytochrome b558 hydrogen channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json NADPH oxidase-associated cytochrome b558 hydrogen channel activity|NADPH oxidase-associated cytochrome b558 proton channel http://purl.obolibrary.org/obo/GO_0015282 GO:0015283 biolink:MolecularActivity obsolete apoptogenic cytochrome c release channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json apoptogenic cytochrome c release channel activity|Bcl-2 http://purl.obolibrary.org/obo/GO_0015283 GO:0015284 biolink:MolecularActivity fructose uniporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015284 UBERON:0034873 biolink:AnatomicalEntity bodily gas Any substance in the body or expelled from the body that is in a gaseous state. go-plus.json gas in anatomical space|portion of gas in anatomical space http://purl.obolibrary.org/obo/UBERON_0034873 UBERON:0034874 biolink:AnatomicalEntity air in respiratory system Any portion of gas located in a part of the respiratory system that is composed primarily of air. go-plus.json respiratory air|respiratory system air http://purl.obolibrary.org/obo/UBERON_0034874 UBERON:0034875 biolink:AnatomicalEntity future pituitary gland go-plus.json pituitary primordium http://purl.obolibrary.org/obo/UBERON_0034875 UBERON:0010899 biolink:AnatomicalEntity synchronous hermaphroditic organism Hermaphroditic organism that produces both male and female gametes at the same time. go-plus.json serially hermaphroditic organism|simultaneous hermaphroditic organism http://purl.obolibrary.org/obo/UBERON_0010899 CHEBI:17428 biolink:ChemicalSubstance (R)-reticuline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17428 CHEBI:17429 biolink:ChemicalSubstance 3-ketosucrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17429 chebi_ph7_3 CHEBI:17426 biolink:ChemicalSubstance 5-dehydro-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17426 CHEBI:17427 biolink:ChemicalSubstance 3-hydroxy-L-aspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_17427 chebi_ph7_3 CHEBI:17424 biolink:ChemicalSubstance 4-carboxy-2-hydroxy-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17424 CHEBI:17425 biolink:ChemicalSubstance 1-pyrroline-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17425 CHEBI:6495 biolink:ChemicalSubstance lipoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_6495 CHEBI:17422 biolink:ChemicalSubstance P(1),P(4)-bis(5'-adenosyl) tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17422 CHEBI:17420 biolink:ChemicalSubstance tetrahydropteroyltri-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17420 CHEBI:17421 biolink:ChemicalSubstance heparan sulfate N-acetyl-alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17421 CHEBI:6499 biolink:ChemicalSubstance lipoxin B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_6499 CHEBI:6497 biolink:ChemicalSubstance lipoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6497 CHEBI:6498 biolink:ChemicalSubstance lipoxin A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_6498 GO:0005901 biolink:CellularComponent caveola A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm. Wikipedia:Caveolae go-plus.json caveolar membrane|caveolae http://purl.obolibrary.org/obo/GO_0005901 GO:0005902 biolink:CellularComponent microvillus Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. Wikipedia:Microvillus|NIF_Subcellular:sao671419673 go-plus.json microvilli http://purl.obolibrary.org/obo/GO_0005902 goslim_pir GO:0005900 biolink:CellularComponent oncostatin-M receptor complex A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta. go-plus.json http://purl.obolibrary.org/obo/GO_0005900 UBERON:0010890 biolink:AnatomicalEntity pelvic complex muscle Muscles of the pelvic girdle, hindlimb or pelvic fin. go-plus.json lower limb muscle|muscle of pelvic girdle and leg|pelvic girdle or posterior limb muscle|pelvic girdle or hind limb muscle|pelvic girdle and hind limb muscles|muscle of lower limb http://purl.obolibrary.org/obo/UBERON_0010890 UBERON:0010891 biolink:AnatomicalEntity pectoral complex muscle A muscle of a pectoral girdle, pectoral fin or anterior limb. go-plus.json muscle of pectoral girdle and wing|muscle of pectoral girdle and limb|muscle of upper limb|pectoral girdle and fore limb muscles|upper limb muscle http://purl.obolibrary.org/obo/UBERON_0010891 UBERON:0010894 biolink:AnatomicalEntity keratinous tooth go-plus.json horny denticle http://purl.obolibrary.org/obo/UBERON_0010894 UBERON:0010893 biolink:AnatomicalEntity median external naris Am unpaired external naris that lies in the midline of the head. go-plus.json median nostril|nasohypophysial opening|median anterior naris http://purl.obolibrary.org/obo/UBERON_0010893 UBERON:0034876 biolink:AnatomicalEntity future neurohypophysis the outgrowth of neuroectoderm located on the floor of the embryonic hypothalamus that gives rise to the neurohypophysis (posterior lobe) of the pituitary gland go-plus.json neurohypophyseal bud|neurohypohysial region http://purl.obolibrary.org/obo/UBERON_0034876 CHEBI:17419 biolink:ChemicalSubstance 3-hydroxy-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17419 UBERON:0034878 biolink:AnatomicalEntity prechordal mesoderm the area of axial mesoderm that develops into the prechordal plate go-plus.json prechordal mesenchyme http://purl.obolibrary.org/obo/UBERON_0034878 CHEBI:17417 biolink:ChemicalSubstance N-caffeoylputrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17417 UBERON:0010885 biolink:AnatomicalEntity hindlimb cartilage element A cartilaginous condensation that has the potential to develop into a hindlimb bone. go-plus.json hindlimb cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010885 UBERON:0010886 biolink:AnatomicalEntity hindlimb pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a hindlimb bone. go-plus.json hindlimb pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010886 CHEBI:17418 biolink:ChemicalSubstance valeric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17418 CHEBI:17415 biolink:ChemicalSubstance 2,5-dioxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17415 CHEBI:17416 biolink:ChemicalSubstance 3,4-dihydroxyphthalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17416 CHEBI:17413 biolink:ChemicalSubstance 2-(hydroxymethyl)-4-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17413 GO:0005909 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005909 CHEBI:17412 biolink:ChemicalSubstance R'C(R)S-S(R)CR' go-plus.json http://purl.obolibrary.org/obo/CHEBI_17412 chebi_ph7_3 GO:0005907 biolink:CellularComponent obsolete HA1 clathrin adaptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json AP1|HA1 clathrin adaptor http://purl.obolibrary.org/obo/GO_0005907 GO:0005908 biolink:CellularComponent obsolete HA2 clathrin adaptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json AP2|HA2 clathrin adaptor http://purl.obolibrary.org/obo/GO_0005908 CHEBI:17410 biolink:ChemicalSubstance pteridine-2,4,6,7-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17410 chebi_ph7_3 GO:0005905 biolink:CellularComponent clathrin-coated pit A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes. NIF_Subcellular:sao1969557946 go-plus.json coated pit http://purl.obolibrary.org/obo/GO_0005905 GO:0005906 biolink:CellularComponent obsolete clathrin adaptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json adaptin|clathrin adaptor http://purl.obolibrary.org/obo/GO_0005906 GO:0005903 biolink:CellularComponent brush border The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell. Wikipedia:Brush_border go-plus.json http://purl.obolibrary.org/obo/GO_0005903 goslim_pir GO:0005904 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005904 UBERON:0010883 biolink:AnatomicalEntity forelimb cartilage element A cartilaginous condensation that has the potential to develop into a forelimb bone. go-plus.json forelimb wing cartilaginous condensation|wing cartilaginous condensation http://purl.obolibrary.org/obo/UBERON_0010883 UBERON:0010884 biolink:AnatomicalEntity forelimb bone pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a forelimb bone. go-plus.json wing bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010884 UBERON:0010881 biolink:AnatomicalEntity limb cartilage element A skeletal element that is part of a limb and composed of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010881 UBERON:0010882 biolink:AnatomicalEntity limb bone pre-cartilage condensation A skeletal element that is part of a limb and composed of pre-cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010882 CHEBI:17448 biolink:ChemicalSubstance methanofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_17448 CHEBI:17446 biolink:ChemicalSubstance 3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17446 CHEBI:17447 biolink:ChemicalSubstance geraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17447 chebi_ph7_3 UBERON:0009891 biolink:AnatomicalEntity facial mesenchyme Mesenchyme that is part of a developing face. go-plus.json mesenchyme of face|face mesenchyme http://purl.obolibrary.org/obo/UBERON_0009891 CHEBI:17445 biolink:ChemicalSubstance 3-hydroxyphenylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17445 CHEBI:17442 biolink:ChemicalSubstance 4-(2-aminophenyl)-2,4-dioxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17442 CHEBI:6472 biolink:ChemicalSubstance lincomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6472 CHEBI:17443 biolink:ChemicalSubstance L-homocitrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17443 CHEBI:17440 biolink:ChemicalSubstance 4-nitrophenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17440 CHEBI:17441 biolink:ChemicalSubstance chlorite go-plus.json http://purl.obolibrary.org/obo/CHEBI_17441 chebi_ph7_3 UBERON:0019206 biolink:AnatomicalEntity tongue papilla epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0019206 UBERON:0019207 biolink:AnatomicalEntity chorioretinal region The part of the eye that consists of both the retina and the optic choroid go-plus.json choroid and retina|retinachoroidal region|chorioretina|retinachoroid http://purl.obolibrary.org/obo/UBERON_0019207 UBERON:0019204 biolink:AnatomicalEntity skin epithelium Any region of epithelium that is part of a skin region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0019204 UBERON:0009887 biolink:AnatomicalEntity interlobar vein The interlobar veins are veins of the renal circulation which drain the renal lobes. go-plus.json interlobar vein of kidney|venae interlobares renis|venae interlobares renis|set of interlobar veins of kidney|interlobar veins of kidney http://purl.obolibrary.org/obo/UBERON_0009887 UBERON:0034898 biolink:AnatomicalEntity alveolar ridge of premaxilla The thickened ridge of bone that contains the tooth sockets on the premaxilla. go-plus.json pars dentalis of premaxilla http://purl.obolibrary.org/obo/UBERON_0034898 UBERON:0009889 biolink:AnatomicalEntity secondary heart field A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). go-plus.json SHF|anterior/second heart field|anterior heart field|second heart field http://purl.obolibrary.org/obo/UBERON_0009889 CHEBI:17439 biolink:ChemicalSubstance cyanocob(III)alamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17439 chebi_ph7_3 CHEBI:17437 biolink:ChemicalSubstance dimethyl sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17437 chebi_ph7_3 CHEBI:17438 biolink:ChemicalSubstance O-beta-D-xylosylzeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17438 chebi_ph7_3 CHEBI:17435 biolink:ChemicalSubstance naphthalene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17435 chebi_ph7_3 CHEBI:17436 biolink:ChemicalSubstance (R)-5-phosphomevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17436 CHEBI:17433 biolink:ChemicalSubstance queuine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17433 UBERON:0009880 biolink:AnatomicalEntity carpal skeleton Subdivision of skeleton that consists of the endochondral elements distal to the anterior limb/fin zeugopodial skeletal elements which constitute the proximal region of the anterior autopod skeleton[PHENOSCAPE:ad]. go-plus.json fore mesopodial skeleton|ossa carpi|set of carpal bones|ossa carpi|fore mesopodium skeleton|carpal bones set|carpal bones|carpus|skeletal parts of fore mesopodium|skeleton of carpus|fore mesopodium http://purl.obolibrary.org/obo/UBERON_0009880 CHEBI:17434 biolink:ChemicalSubstance trimethylsulfonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_17434 chebi_ph7_3 CHEBI:17431 biolink:ChemicalSubstance agmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17431 UBERON:0009881 biolink:AnatomicalEntity anterior lateral plate mesoderm go-plus.json ALPM http://purl.obolibrary.org/obo/UBERON_0009881 UBERON:0009883 biolink:AnatomicalEntity medullary ray A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla. go-plus.json Ferrein's pyramid|kidney medullary ray|renal medullary ray http://purl.obolibrary.org/obo/UBERON_0009883 UBERON:0009885 biolink:AnatomicalEntity interlobar artery An artery that supplies a renal lobe. go-plus.json arteriae interlobares renis|set of interlobar arteries of kidney|arteriae interlobares renis|renal interlobar artery|interlobar artery of kidney|interlobar arteries of kidney|kidney interlobar artery http://purl.obolibrary.org/obo/UBERON_0009885 UBERON:0019269 biolink:AnatomicalEntity gray matter of diencephalon go-plus.json http://purl.obolibrary.org/obo/UBERON_0019269 UBERON:0019267 biolink:AnatomicalEntity gray matter of midbrain go-plus.json http://purl.obolibrary.org/obo/UBERON_0019267 UBERON:0019264 biolink:AnatomicalEntity gray matter of forebrain go-plus.json http://purl.obolibrary.org/obo/UBERON_0019264 UBERON:0019262 biolink:AnatomicalEntity white matter of myelencephalon A white matter that is part of the myelencephalon. go-plus.json myelencephalic white matter http://purl.obolibrary.org/obo/UBERON_0019262 UBERON:0019263 biolink:AnatomicalEntity gray matter of hindbrain go-plus.json gray matter of the hindbrain http://purl.obolibrary.org/obo/UBERON_0019263 UBERON:0019261 biolink:AnatomicalEntity white matter of forebrain A white matter that is part of the forebrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0019261 UBERON:0019258 biolink:AnatomicalEntity white matter of hindbrain A white matter that is part of the hindbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0019258 CHEBI:17408 biolink:ChemicalSubstance monoacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17408 chebi_ph7_3 CHEBI:17409 biolink:ChemicalSubstance 10-hydroxycapric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17409 CHEBI:17406 biolink:ChemicalSubstance 3-(imidazol-5-yl)pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17406 CHEBI:17407 biolink:ChemicalSubstance 2-trans,6-trans-farnesyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17407 CHEBI:17404 biolink:ChemicalSubstance indan-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17404 chebi_ph7_3 CHEBI:17405 biolink:ChemicalSubstance 4-pyridoxic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17405 CHEBI:17402 biolink:ChemicalSubstance 2-methylpropanoyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17402 CHEBI:17403 biolink:ChemicalSubstance 3-chloro-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17403 CHEBI:17400 biolink:ChemicalSubstance raucaffricine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17400 chebi_ph7_3 CHEBI:17401 biolink:ChemicalSubstance myo-inositol hexakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17401 NCBITaxon:2682553 biolink:OrganismalEntity Amphioxiformes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2682553 NCBITaxon:2682552 biolink:OrganismalEntity Leptocardii go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2682552 GO:0030813 biolink:BiologicalProcess positive regulation of nucleotide catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. go-plus.json upregulation of nucleotide catabolic process|stimulation of nucleotide catabolic process|up-regulation of nucleotide catabolic process|activation of nucleotide catabolic process|positive regulation of nucleotide degradation|positive regulation of nucleotide breakdown|positive regulation of nucleotide catabolism|up regulation of nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0030813 GO:0005857 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005857 GO:0005858 biolink:CellularComponent axonemal dynein complex A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. go-plus.json axonemal dynein heavy chain|axonemal dynein intermediate light chain|axonemal dynein light chain|axonemal dynein intermediate chain http://purl.obolibrary.org/obo/GO_0005858 GO:0030814 biolink:BiologicalProcess obsolete regulation of cAMP metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json regulation of 3',5' cAMP metabolism|regulation of 3',5'-cAMP metabolic process|regulation of cyclic AMP metabolism|regulation of adenosine 3',5'-cyclophosphate metabolic process|regulation of cAMP metabolism|regulation of adenosine 3',5'-cyclophosphate metabolism|regulation of cyclic AMP metabolic process|regulation of 3',5'-cAMP metabolism|regulation of 3',5' cAMP metabolic process http://purl.obolibrary.org/obo/GO_0030814 CHEBI:17393 biolink:ChemicalSubstance D-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17393 GO:0030811 biolink:BiologicalProcess regulation of nucleotide catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. go-plus.json regulation of nucleotide catabolism|regulation of nucleotide degradation|regulation of nucleotide breakdown http://purl.obolibrary.org/obo/GO_0030811 CHEBI:17390 biolink:ChemicalSubstance allocryptopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17390 chebi_ph7_3 GO:0005855 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005855 GO:0030812 biolink:BiologicalProcess negative regulation of nucleotide catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. go-plus.json down regulation of nucleotide catabolic process|inhibition of nucleotide catabolic process|negative regulation of nucleotide degradation|negative regulation of nucleotide breakdown|down-regulation of nucleotide catabolic process|downregulation of nucleotide catabolic process|negative regulation of nucleotide catabolism http://purl.obolibrary.org/obo/GO_0030812 GO:0005856 biolink:CellularComponent cytoskeleton Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. Wikipedia:Cytoskeleton go-plus.json http://purl.obolibrary.org/obo/GO_0005856 goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon CHEBI:17391 biolink:ChemicalSubstance 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_17391 chebi_ph7_3 GO:0005853 biolink:CellularComponent eukaryotic translation elongation factor 1 complex A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma. go-plus.json http://purl.obolibrary.org/obo/GO_0005853 GO:0005854 biolink:CellularComponent nascent polypeptide-associated complex A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome. go-plus.json NACA|NAC http://purl.obolibrary.org/obo/GO_0005854 GO:0030810 biolink:BiologicalProcess positive regulation of nucleotide biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. go-plus.json positive regulation of nucleotide synthesis|positive regulation of nucleotide formation|up-regulation of nucleotide biosynthetic process|upregulation of nucleotide biosynthetic process|up regulation of nucleotide biosynthetic process|positive regulation of nucleotide biosynthesis|positive regulation of nucleotide anabolism|activation of nucleotide biosynthetic process|stimulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0030810 GO:0005851 biolink:CellularComponent eukaryotic translation initiation factor 2B complex A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon. go-plus.json eif2B|eIF-2B http://purl.obolibrary.org/obo/GO_0005851 GO:0005852 biolink:CellularComponent eukaryotic translation initiation factor 3 complex A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. go-plus.json eIF3|eIF-3 http://purl.obolibrary.org/obo/GO_0005852 GO:0005850 biolink:CellularComponent eukaryotic translation initiation factor 2 complex Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA. Wikipedia:EIF-2 go-plus.json eIF2|eIF-2 http://purl.obolibrary.org/obo/GO_0005850 GO:0030819 biolink:BiologicalProcess obsolete positive regulation of cAMP biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json upregulation of cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthesis|positive regulation of cyclic AMP biosynthetic process|positive regulation of cyclic AMP biosynthesis|up regulation of cAMP biosynthetic process|positive regulation of cAMP anabolism|activation of cAMP biosynthetic process|positive regulation of adenosine 3',5'-cyclophosphate biosynthesis|positive regulation of adenosine 3',5'-cyclophosphate biosynthetic process|positive regulation of cAMP biosynthesis|positive regulation of cAMP synthesis|positive regulation of 3',5'-cAMP biosynthesis|stimulation of cAMP biosynthetic process|positive regulation of 3',5'-cAMP biosynthetic process|positive regulation of cAMP formation|up-regulation of cAMP biosynthetic process http://purl.obolibrary.org/obo/GO_0030819 CHEBI:42355 biolink:ChemicalSubstance erythromycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_42355 GO:0030817 biolink:BiologicalProcess obsolete regulation of cAMP biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json regulation of cyclic AMP biosynthesis|regulation of cyclic AMP biosynthetic process|regulation of adenosine 3',5'-cyclophosphate biosynthesis|regulation of adenosine 3',5'-cyclophosphate biosynthetic process|regulation of cAMP biosynthesis|regulation of 3',5'-cAMP biosynthetic process|regulation of 3',5'-cAMP biosynthesis|regulation of cAMP anabolism|regulation of cAMP synthesis|regulation of cAMP formation|regulation of 3',5' cAMP biosynthesis|regulation of 3',5' cAMP biosynthetic process http://purl.obolibrary.org/obo/GO_0030817 GO:0030818 biolink:BiologicalProcess obsolete negative regulation of cAMP biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json down regulation of cAMP biosynthetic process|negative regulation of 3',5' cAMP biosynthetic process|negative regulation of cAMP anabolism|negative regulation of 3',5' cAMP biosynthesis|downregulation of cAMP biosynthetic process|negative regulation of cAMP synthesis|negative regulation of cyclic AMP biosynthesis|negative regulation of cyclic AMP biosynthetic process|negative regulation of cAMP formation|down-regulation of cAMP biosynthetic process|negative regulation of cAMP biosynthesis|negative regulation of adenosine 3',5'-cyclophosphate biosynthetic process|negative regulation of adenosine 3',5'-cyclophosphate biosynthesis|negative regulation of 3',5'-cAMP biosynthetic process|negative regulation of 3',5'-cAMP biosynthesis|inhibition of cAMP biosynthetic process http://purl.obolibrary.org/obo/GO_0030818 GO:0030815 biolink:BiologicalProcess obsolete negative regulation of cAMP metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json negative regulation of cyclic AMP metabolic process|downregulation of cAMP metabolic process|negative regulation of 3',5' cAMP metabolic process|down regulation of cAMP metabolic process|negative regulation of 3',5' cAMP metabolism|inhibition of cAMP metabolic process|negative regulation of cyclic AMP metabolism|negative regulation of cAMP metabolism|negative regulation of adenosine 3',5'-cyclophosphate metabolism|negative regulation of 3',5'-cAMP metabolism|negative regulation of 3',5'-cAMP metabolic process|down-regulation of cAMP metabolic process|negative regulation of adenosine 3',5'-cyclophosphate metabolic process http://purl.obolibrary.org/obo/GO_0030815 GO:0030816 biolink:BiologicalProcess obsolete positive regulation of cAMP metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json positive regulation of 3',5'-cAMP metabolic process|positive regulation of adenosine 3',5'-cyclophosphate metabolic process|up regulation of cAMP metabolic process|positive regulation of cyclic AMP metabolic process|positive regulation of 3',5' cAMP metabolism|positive regulation of 3',5' cAMP metabolic process|upregulation of cAMP metabolic process|positive regulation of cyclic AMP metabolism|positive regulation of cAMP metabolism|positive regulation of adenosine 3',5'-cyclophosphate metabolism|stimulation of cAMP metabolic process|positive regulation of 3',5'-cAMP metabolism|up-regulation of cAMP metabolic process|activation of cAMP metabolic process http://purl.obolibrary.org/obo/GO_0030816 UBERON:0009953 biolink:AnatomicalEntity post-embryonic organism A multicellular organism that existence_starts_with a post-embryonic stage. go-plus.json post-natal organism|postnatal mouse|TS28 mouse|post-hatching organism|postnatal organism http://purl.obolibrary.org/obo/UBERON_0009953 UBERON:0009955 biolink:AnatomicalEntity neurogenic placode Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia. go-plus.json placodae neurogenicae|neurogenic placodes http://purl.obolibrary.org/obo/UBERON_0009955 UBERON:0034901 biolink:AnatomicalEntity cervical sympathetic nerve trunk The cervical ganglia are paravertebral ganglia of the sympathetic nervous system. These emerging postganglionic nerves synapse with preganglionic nerves from the thoracic spinal cord. They consist of three paravertebral ganglia: superior cervical ganglion middle cervical ganglion inferior cervical ganglion. The inferior ganglion may be fused with the first thoracic ganglion to form a single structure, the stellate ganglion. Nerves emerging from cervical sympathetic ganglia contribute to the cardiac plexus, among other things. go-plus.json cervical sympathetic trunk|cervical sympathetic chain|cervical part of sympathetic trunk http://purl.obolibrary.org/obo/UBERON_0034901 UBERON:0034903 biolink:AnatomicalEntity left atrium endocardium Endocardium that is part of the left atrium. go-plus.json endocardium of left atrium|left atrium endocardial tissue|left atrial endocardium http://purl.obolibrary.org/obo/UBERON_0034903 UBERON:0009958 biolink:AnatomicalEntity bladder lumen A anatomical space that is enclosed by a urinary bladder. go-plus.json urinary bladder lumen|lumen of urinary bladder|bladder cavity|cavity of urinary bladder http://purl.obolibrary.org/obo/UBERON_0009958 UBERON:0034905 biolink:AnatomicalEntity gland lumen go-plus.json lumen of gland http://purl.obolibrary.org/obo/UBERON_0034905 CHEBI:17389 biolink:ChemicalSubstance 2-monoglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_17389 chebi_ph7_3 UBERON:0034907 biolink:AnatomicalEntity pineal parenchyma Parenchymal tissue that forms the pineal gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034907 UBERON:0034908 biolink:AnatomicalEntity scapular muscle Any of the muscles that are responsible for moving the scapula. In humans these are the levator scapulae, the infraspinatus muscle, the teres major, the teres minor, and the supraspinatus muscle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034908 CHEBI:17387 biolink:ChemicalSubstance O-acylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17387 CHEBI:17388 biolink:ChemicalSubstance (S)-1-pyrroline-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17388 chebi_ph7_3 UBERON:0034909 biolink:AnatomicalEntity intermaxillary suture A cranial suture in the midline of the skull that connects the left and right maxilla bones go-plus.json intermaxillary suture of skull http://purl.obolibrary.org/obo/UBERON_0034909 CHEBI:17385 biolink:ChemicalSubstance 3-(4-hydroxyphenyl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17385 GO:0005859 biolink:CellularComponent muscle myosin complex A filament of myosin found in a muscle cell of any type. go-plus.json http://purl.obolibrary.org/obo/GO_0005859 CHEBI:17383 biolink:ChemicalSubstance GDP-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17383 CHEBI:17384 biolink:ChemicalSubstance 17-O-acetylnorajmaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17384 GO:0030802 biolink:BiologicalProcess obsolete regulation of cyclic nucleotide biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides. go-plus.json regulation of cyclic nucleotide biosynthesis|regulation of cyclic nucleotide anabolism|regulation of cyclic nucleotide synthesis|regulation of cyclic nucleotide formation http://purl.obolibrary.org/obo/GO_0030802 GO:0005868 biolink:CellularComponent cytoplasmic dynein complex Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains. go-plus.json cytoplasmic dynein intermediate chain|cytoplasmic dynein heavy chain|cytoplasmic dynein intermediate light chain|cytoplasmic dynein light chain http://purl.obolibrary.org/obo/GO_0005868 CHEBI:17381 biolink:ChemicalSubstance porphobilinogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_17381 GO:0030803 biolink:BiologicalProcess obsolete negative regulation of cyclic nucleotide biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides. go-plus.json negative regulation of cyclic nucleotide anabolism|negative regulation of cyclic nucleotide synthesis|negative regulation of cyclic nucleotide formation|downregulation of cyclic nucleotide biosynthetic process|down regulation of cyclic nucleotide biosynthetic process|inhibition of cyclic nucleotide biosynthetic process|down-regulation of cyclic nucleotide biosynthetic process|negative regulation of cyclic nucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0030803 GO:0005869 biolink:CellularComponent dynactin complex A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach. go-plus.json http://purl.obolibrary.org/obo/GO_0005869 CHEBI:17382 biolink:ChemicalSubstance 5'-O-beta-D-glucosylpyridoxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17382 chebi_ph7_3 GO:0030800 biolink:BiologicalProcess obsolete negative regulation of cyclic nucleotide metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides. go-plus.json negative regulation of cyclic nucleotide metabolism|down regulation of cyclic nucleotide metabolic process|downregulation of cyclic nucleotide metabolic process|down-regulation of cyclic nucleotide metabolic process|inhibition of cyclic nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0030800 GO:0030801 biolink:BiologicalProcess obsolete positive regulation of cyclic nucleotide metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides. go-plus.json positive regulation of cyclic nucleotide metabolism|upregulation of cyclic nucleotide metabolic process|up regulation of cyclic nucleotide metabolic process|activation of cyclic nucleotide metabolic process|stimulation of cyclic nucleotide metabolic process|up-regulation of cyclic nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0030801 CHEBI:17380 biolink:ChemicalSubstance 3-hydroxy-L-kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17380 GO:0005865 biolink:CellularComponent striated muscle thin filament Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005865 GO:0005862 biolink:CellularComponent muscle thin filament tropomyosin A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0005862 GO:0005863 biolink:CellularComponent striated muscle myosin thick filament Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005863 GO:0005860 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005860 GO:0005861 biolink:CellularComponent troponin complex A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0005861 GO:0030808 biolink:BiologicalProcess regulation of nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. go-plus.json regulation of nucleotide formation|regulation of nucleotide biosynthesis|regulation of nucleotide anabolism|regulation of nucleotide synthesis http://purl.obolibrary.org/obo/GO_0030808 GO:0030809 biolink:BiologicalProcess negative regulation of nucleotide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. go-plus.json down regulation of nucleotide biosynthetic process|downregulation of nucleotide biosynthetic process|negative regulation of nucleotide anabolism|negative regulation of nucleotide synthesis|negative regulation of nucleotide formation|down-regulation of nucleotide biosynthetic process|negative regulation of nucleotide biosynthesis|inhibition of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0030809 GO:0030806 biolink:BiologicalProcess obsolete negative regulation of cyclic nucleotide catabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides. go-plus.json inhibition of cyclic nucleotide catabolic process|down regulation of cyclic nucleotide catabolic process|downregulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide degradation|negative regulation of cyclic nucleotide breakdown|down-regulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide catabolism http://purl.obolibrary.org/obo/GO_0030806 GO:0030807 biolink:BiologicalProcess obsolete positive regulation of cyclic nucleotide catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides. go-plus.json positive regulation of cyclic nucleotide catabolism|up-regulation of cyclic nucleotide catabolic process|upregulation of cyclic nucleotide catabolic process|positive regulation of cyclic nucleotide degradation|positive regulation of cyclic nucleotide breakdown|up regulation of cyclic nucleotide catabolic process|activation of cyclic nucleotide catabolic process|stimulation of cyclic nucleotide catabolic process http://purl.obolibrary.org/obo/GO_0030807 CHEBI:66331 biolink:ChemicalSubstance xanthohumol go-plus.json http://purl.obolibrary.org/obo/CHEBI_66331 GO:0030804 biolink:BiologicalProcess obsolete positive regulation of cyclic nucleotide biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides. go-plus.json positive regulation of cyclic nucleotide synthesis|positive regulation of cyclic nucleotide biosynthesis|positive regulation of cyclic nucleotide formation|up regulation of cyclic nucleotide biosynthetic process|upregulation of cyclic nucleotide biosynthetic process|stimulation of cyclic nucleotide biosynthetic process|up-regulation of cyclic nucleotide biosynthetic process|activation of cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide anabolism http://purl.obolibrary.org/obo/GO_0030804 GO:0030805 biolink:BiologicalProcess regulation of cyclic nucleotide catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides. go-plus.json regulation of cyclic nucleotide catabolism|regulation of cyclic nucleotide degradation|regulation of cyclic nucleotide breakdown http://purl.obolibrary.org/obo/GO_0030805 CHEBI:17378 biolink:ChemicalSubstance D-glyceraldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17378 chebi_ph7_3 CHEBI:17379 biolink:ChemicalSubstance isovitexin 2''-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_17379 CHEBI:17376 biolink:ChemicalSubstance cystine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17376 CHEBI:17377 biolink:ChemicalSubstance bergaptol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17377 CHEBI:17374 biolink:ChemicalSubstance N(6)-acetyl-N(6)-hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17374 CHEBI:17375 biolink:ChemicalSubstance (2S)-2-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17375 CHEBI:17372 biolink:ChemicalSubstance 1,2-dihydrovomilenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17372 chebi_ph7_3 GO:0005835 biolink:CellularComponent fatty acid synthase complex A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA. Wikipedia:Fatty_acid_synthetase_complex go-plus.json holo-[acyl-carrier-protein] synthase complex|cytosolic type I fatty acid synthase complex|cytosolic type I FAS complex|FAS complex|cytosolic FAS complex|cytosolic fatty acid synthase complex|fatty acid synthetase complex http://purl.obolibrary.org/obo/GO_0005835 goslim_pir GO:0005836 biolink:CellularComponent fatty-acyl-CoA synthase complex A protein complex that possesses fatty-acyl-CoA synthase activity. go-plus.json fatty acyl CoA synthase complex http://purl.obolibrary.org/obo/GO_0005836 GO:0005833 biolink:CellularComponent hemoglobin complex An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group. go-plus.json haemoglobin complex http://purl.obolibrary.org/obo/GO_0005833 GO:0005834 biolink:CellularComponent heterotrimeric G-protein complex Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. go-plus.json heterotrimeric G-protein GTPase, gamma-subunit|heterotrimeric G-protein GTPase activity|heterotrimeric G-protein GTPase, alpha-subunit|heterotrimeric G-protein GTPase, beta-subunit http://purl.obolibrary.org/obo/GO_0005834 GO:0005831 biolink:CellularComponent steroid hormone aporeceptor complex A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0005831 GO:0005832 biolink:CellularComponent chaperonin-containing T-complex A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor. go-plus.json CCT particle|TriC http://purl.obolibrary.org/obo/GO_0005832 GO:0005830 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005830 CHEBI:91309 biolink:ChemicalSubstance lysophosphatidylcholine(18:2/0:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91309 chebi_ph7_3 UBERON:0034921 biolink:AnatomicalEntity multi organ part structure An multicellular anatomical structure that has subparts of multiple organs as a part. go-plus.json anatomical cluster http://purl.obolibrary.org/obo/UBERON_0034921 UBERON:0034922 biolink:AnatomicalEntity cell cluster A cluster of cells, largely surrounded by a morphological boundary. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034922 UBERON:0034923 biolink:AnatomicalEntity disconnected anatomical group Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034923 UBERON:0010913 biolink:AnatomicalEntity vertebral element Skeletal element that forms around the notochord and is part of the vertebral column. go-plus.json vertebral endochondral element|vertebra element|vertebra endochondral element|vertebra skeletal element http://purl.obolibrary.org/obo/UBERON_0010913 CHEBI:91306 biolink:ChemicalSubstance (20S,23)-dihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_91306 chebi_ph7_3 UBERON:0034925 biolink:AnatomicalEntity anatomical collection A collection of anatomical structures that are alike in terms of their morphology or developmental origin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034925 UBERON:0010911 biolink:AnatomicalEntity ossicle Skeletal element that is often isolated, small, and variable in composition. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010911 CHEBI:91307 biolink:ChemicalSubstance (20S,23,24)-trihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_91307 chebi_ph7_3 UBERON:0034926 biolink:AnatomicalEntity anatomical row An anatomical collection that is arranged in a line. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034926 UBERON:0010912 biolink:AnatomicalEntity subdivision of skeleton Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. go-plus.json subdivision of skeleton (in vivo)|skeletal subdivision http://purl.obolibrary.org/obo/UBERON_0010912 CHEBI:91308 biolink:ChemicalSubstance (20S,23,25)-trihydroxyvitamin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_91308 chebi_ph7_3 UBERON:0034928 biolink:AnatomicalEntity dorsal surface of penis go-plus.json dorsum penis|dorsum of penis http://purl.obolibrary.org/obo/UBERON_0034928 CHEBI:91301 biolink:ChemicalSubstance 5,20-diHEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91301 chebi_ph7_3 CHEBI:91302 biolink:ChemicalSubstance lysophosphatidylcholine(0:0/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91302 chebi_ph7_3 UBERON:0034929 biolink:AnatomicalEntity external soft tissue zone A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034929 CHEBI:91303 biolink:ChemicalSubstance lysophosphatidylcholine(0:0/20:4) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91303 chebi_ph7_3 GO:0005839 biolink:CellularComponent proteasome core complex A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. go-plus.json 20S proteasome|PA28gamma-20S proteasome|macropain|20S core complex http://purl.obolibrary.org/obo/GO_0005839 goslim_metagenomics GO:0005837 biolink:CellularComponent obsolete 26S proteasome OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome. go-plus.json 26S proteasome http://purl.obolibrary.org/obo/GO_0005837 GO:0005838 biolink:CellularComponent proteasome regulatory particle A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex. go-plus.json PA700 proteasome activator|modulator complex|PA700-dependent proteasome activator|19S regulatory particle http://purl.obolibrary.org/obo/GO_0005838 CHEBI:91300 biolink:ChemicalSubstance (9Z,12R)-12,18-dihydroxyoctadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91300 chebi_ph7_3 GO:0005846 biolink:CellularComponent nuclear cap binding complex A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export. go-plus.json mRNA cap binding complex|CBC|NCBP-NIP1 complex|snRNA cap binding complex http://purl.obolibrary.org/obo/GO_0005846 GO:0005847 biolink:CellularComponent mRNA cleavage and polyadenylation specificity factor complex A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. go-plus.json CPSF complex|cleavage and polyadenylylation specificity factor activity|CPF complex|CFII complex http://purl.obolibrary.org/obo/GO_0005847 GO:0005844 biolink:CellularComponent polysome A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. Wikipedia:Polysome|NIF_Subcellular:sao1038025871 go-plus.json polyribosome http://purl.obolibrary.org/obo/GO_0005844 goslim_pir GO:0005845 biolink:CellularComponent mRNA cap binding complex Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA. go-plus.json mRNA cap complex http://purl.obolibrary.org/obo/GO_0005845 GO:0005842 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005842 GO:0005843 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005843 GO:0005840 biolink:CellularComponent ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. Wikipedia:Ribosome|NIF_Subcellular:sao1429207766 go-plus.json free ribosome|ribosomal RNA|membrane bound ribosome http://purl.obolibrary.org/obo/GO_0005840 goslim_metagenomics|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_plant|goslim_pir UBERON:0009917 biolink:AnatomicalEntity kidney corticomedullary boundary The region demarcating the renal medulla from the surrounding cortex; end-stage renal failure may be associated with loss of the normal corticomedullary boundary go-plus.json http://purl.obolibrary.org/obo/UBERON_0009917 UBERON:0009918 biolink:AnatomicalEntity retrotrapezoid nucleus The loose collection of neurons that reside in the rostral medulla close to the medullary surface, ventral and immediately caudal of nVII, that are crucial for CO2 sensing in the brain go-plus.json http://purl.obolibrary.org/obo/UBERON_0009918 UBERON:0009919 biolink:AnatomicalEntity ureter smooth muscle The smooth muscle tissue surrounding the epithelium of the ureter go-plus.json ureteral smooth muscle layer|ureteral smooth muscle http://purl.obolibrary.org/obo/UBERON_0009919 UBERON:0009920 biolink:AnatomicalEntity optic neural crest go-plus.json http://purl.obolibrary.org/obo/UBERON_0009920 UBERON:0034932 biolink:AnatomicalEntity epithelium of biliary system The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts. go-plus.json biliary epithelium|biliary system epithelium|biliary tract epithelium http://purl.obolibrary.org/obo/UBERON_0034932 UBERON:0034933 biolink:AnatomicalEntity layer of smooth muscle tissue Any organ component layer that consists of smooth muscle tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034933 UBERON:0010905 biolink:AnatomicalEntity clavicle bone primordium A primordium that develops into a clavicle bone. go-plus.json clavicle primordium http://purl.obolibrary.org/obo/UBERON_0010905 CHEBI:17399 biolink:ChemicalSubstance L-xylulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17399 chebi_ph7_3 CHEBI:17396 biolink:ChemicalSubstance (R)-prunasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17396 chebi_ph7_3 CHEBI:17397 biolink:ChemicalSubstance 3-methyloxindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_17397 chebi_ph7_3 GO:0005848 biolink:CellularComponent mRNA cleavage stimulating factor complex A protein complex required for mRNA cleavage but not for poly(A) addition. go-plus.json cleavage stimulation factor activity|CstF complex http://purl.obolibrary.org/obo/GO_0005848 CHEBI:17394 biolink:ChemicalSubstance N(5)-ethyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17394 GO:0005849 biolink:CellularComponent mRNA cleavage factor complex Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0005849 goslim_pir CHEBI:17395 biolink:ChemicalSubstance cis-caffeic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17395 GO:0005813 biolink:CellularComponent centrosome A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. Wikipedia:Centrosome go-plus.json http://purl.obolibrary.org/obo/GO_0005813 goslim_pir GO:0005814 biolink:CellularComponent centriole A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle. Wikipedia:Centriole|NIF_Subcellular:sao95019936 go-plus.json daughter centriole|mother centriole http://purl.obolibrary.org/obo/GO_0005814 GO:0005811 biolink:CellularComponent lipid droplet An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. go-plus.json adiposome|lipid particle|lipid body http://purl.obolibrary.org/obo/GO_0005811 goslim_chembl|goslim_generic UBERON:0019310 biolink:AnatomicalEntity glossopharyngeal nerve root go-plus.json glossopharyngeal nerve root http://purl.obolibrary.org/obo/UBERON_0019310 UBERON:0019311 biolink:AnatomicalEntity root of olfactory nerve The initial segment of an olfactory nerve, leaving the central nervous system. go-plus.json olfactory nerve root http://purl.obolibrary.org/obo/UBERON_0019311 GO:0005810 biolink:CellularComponent obsolete endocytotic transport vesicle OBSOLETE. (Was not defined before being made obsolete). go-plus.json endocytotic transport vesicle http://purl.obolibrary.org/obo/GO_0005810 CHEBI:32988 biolink:ChemicalSubstance amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_32988 UBERON:0019319 biolink:AnatomicalEntity exocrine gland of integumental system An exocrine gland that is part of a integumental system. go-plus.json integumental system exocrine gland|integumental exocrine gland http://purl.obolibrary.org/obo/UBERON_0019319 CHEBI:32989 biolink:ChemicalSubstance N(omega)-phosphohypotaurocyamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32989 UBERON:0010982 biolink:AnatomicalEntity latissimus dorsi pre-muscle mass go-plus.json http://purl.obolibrary.org/obo/UBERON_0010982 UBERON:0010983 biolink:AnatomicalEntity levator scapulae pre-muscle mass go-plus.json http://purl.obolibrary.org/obo/UBERON_0010983 PR:000004580 biolink:Protein beta-2-microglobulin A protein that is a translation product of the human B2M gene or a 1:1 ortholog thereof. go-plus.json B2M http://purl.obolibrary.org/obo/PR_000004580 UBERON:0019315 biolink:AnatomicalEntity meibum an oily substance that prevents evaporation of the eye's tear film go-plus.json tarsal gland secretion http://purl.obolibrary.org/obo/UBERON_0019315 CHEBI:32980 biolink:ChemicalSubstance phloretic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32980 CHEBI:17349 biolink:ChemicalSubstance 5-methyl-5,6,7,8-tetrahydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17349 CHEBI:17347 biolink:ChemicalSubstance testosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17347 chebi_ph7_3 CHEBI:17348 biolink:ChemicalSubstance D-aldohexose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17348 CHEBI:17345 biolink:ChemicalSubstance guanosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17345 CHEBI:17346 biolink:ChemicalSubstance 4-chlorophenylacetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_17346 chebi_ph7_3 GO:0005819 biolink:CellularComponent spindle The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. Wikipedia:Spindle_apparatus go-plus.json http://purl.obolibrary.org/obo/GO_0005819 CHEBI:17343 biolink:ChemicalSubstance cis-3,4-leucopelargonidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17343 chebi_ph7_3 CHEBI:17344 biolink:ChemicalSubstance 2-carboxy-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17344 GO:0005817 biolink:CellularComponent obsolete centrosomal mitotic factor OBSOLETE. (Was not defined before being made obsolete). go-plus.json centrosomal mitotic factor http://purl.obolibrary.org/obo/GO_0005817 GO:0005818 biolink:CellularComponent aster An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores. go-plus.json http://purl.obolibrary.org/obo/GO_0005818 CHEBI:17342 biolink:ChemicalSubstance L-2-aminohexano-6-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_17342 GO:0005815 biolink:CellularComponent microtubule organizing center An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. Wikipedia:Microtubule_organizing_center go-plus.json MTOC|microtubule organising centre http://purl.obolibrary.org/obo/GO_0005815 goslim_chembl|goslim_yeast|goslim_candida|goslim_generic CHEBI:17340 biolink:ChemicalSubstance cetraxate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17340 GO:0005816 biolink:CellularComponent spindle pole body The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome. Wikipedia:Spindle_pole_body go-plus.json SPB http://purl.obolibrary.org/obo/GO_0005816 GO:0005824 biolink:CellularComponent outer plaque of spindle pole body One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0005824 GO:0005825 biolink:CellularComponent half bridge of spindle pole body Structure adjacent to the plaques of the spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0005825 GO:0005822 biolink:CellularComponent inner plaque of spindle pole body One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0005822 GO:0005823 biolink:CellularComponent central plaque of spindle pole body One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0005823 GO:0005821 biolink:CellularComponent intermediate layer of spindle pole body Structure between the central and outer plaques of the spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0005821 UBERON:0019307 biolink:AnatomicalEntity epithelium of external nose Epithelial layer that is part of the external part of the nose. go-plus.json epithelium of skin of external nose http://purl.obolibrary.org/obo/UBERON_0019307 UBERON:0019306 biolink:AnatomicalEntity nose epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0019306 UBERON:0019304 biolink:AnatomicalEntity sensory organ epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0019304 UBERON:0010963 biolink:AnatomicalEntity trunk and cervical myotome group go-plus.json http://purl.obolibrary.org/obo/UBERON_0010963 CHEBI:17338 biolink:ChemicalSubstance CDP-3,6-dideoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17338 CHEBI:17339 biolink:ChemicalSubstance N(5)-acyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17339 CHEBI:17336 biolink:ChemicalSubstance all-trans-retinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17336 chebi_ph7_3 CHEBI:17337 biolink:ChemicalSubstance (2-chloro-5-oxo-2,5-dihydro-2-furyl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17337 CHEBI:17334 biolink:ChemicalSubstance penicillin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17334 CHEBI:17335 biolink:ChemicalSubstance 4-O-beta-D-glucosyl-4-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17335 CHEBI:17332 biolink:ChemicalSubstance planteose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17332 chebi_ph7_3 CHEBI:17333 biolink:ChemicalSubstance chorismic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17333 GO:0005828 biolink:CellularComponent kinetochore microtubule Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation. go-plus.json pole-to-kinetochore microtubule http://purl.obolibrary.org/obo/GO_0005828 GO:0005829 biolink:CellularComponent cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. Wikipedia:Cytosol|NIF_Subcellular:sao101633890 go-plus.json http://purl.obolibrary.org/obo/GO_0005829 goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr CHEBI:17331 biolink:ChemicalSubstance N-benzoylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17331 chebi_ph7_3 GO:0005826 biolink:CellularComponent actomyosin contractile ring A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis. go-plus.json cytokinetic ring|actomyosin ring|CAR|constriction ring|contractile actomyosin ring http://purl.obolibrary.org/obo/GO_0005826 CHEBI:91310 biolink:ChemicalSubstance lysophosphatidylcholine(20:4/0:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91310 chebi_ph7_3 GO:0005827 biolink:CellularComponent polar microtubule Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart. go-plus.json pole-to-pole microtubule http://purl.obolibrary.org/obo/GO_0005827 CHEBI:17371 biolink:ChemicalSubstance macrocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17371 CHEBI:32964 biolink:ChemicalSubstance ornithinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32964 CHEBI:32965 biolink:ChemicalSubstance N(3')-acetylgentamycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_32965 CHEBI:32966 biolink:ChemicalSubstance beta-D-fructofuranose 1,6-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_32966 chebi_ph7_3 CHEBI:32969 biolink:ChemicalSubstance D-lombricine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32969 UBERON:0010955 biolink:AnatomicalEntity trapezius pre-muscle mass go-plus.json http://purl.obolibrary.org/obo/UBERON_0010955 CHEBI:17369 biolink:ChemicalSubstance D-mannose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17369 CHEBI:32963 biolink:ChemicalSubstance amidinoproclavaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32963 CHEBI:17367 biolink:ChemicalSubstance 2-hydroxy-6-oxonona-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17367 CHEBI:17368 biolink:ChemicalSubstance hypoxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17368 chebi_ph7_3 UBERON:0010959 biolink:AnatomicalEntity craniocervical muscle Any muscle organ that is part of either the head or the neck. go-plus.json muscle of head or neck|muscle of head and neck http://purl.obolibrary.org/obo/UBERON_0010959 CHEBI:17365 biolink:ChemicalSubstance 2,4-dichloro-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17365 UBERON:0009970 biolink:AnatomicalEntity epithelium of pancreatic duct An epithelium that is part of a pancreatic duct. go-plus.json pancreatic duct epithelium|pancreatic ductal epithelium http://purl.obolibrary.org/obo/UBERON_0009970 CHEBI:17363 biolink:ChemicalSubstance D-ribulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17363 UBERON:0009972 biolink:AnatomicalEntity ureteropelvic junction The junction between the ureter and the renal pelvis of the kidney go-plus.json pelvoureteric junction|pelviureteric junction http://purl.obolibrary.org/obo/UBERON_0009972 CHEBI:17364 biolink:ChemicalSubstance D-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17364 UBERON:0009973 biolink:AnatomicalEntity ureterovesical junction The valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney go-plus.json vesico-ureteral junction|vesicoureteric junction|vesico-ureteric junction http://purl.obolibrary.org/obo/UBERON_0009973 CHEBI:17361 biolink:ChemicalSubstance cytidine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17361 CHEBI:17362 biolink:ChemicalSubstance quinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17362 chebi_ph7_3 UBERON:0009974 biolink:AnatomicalEntity lumen of Rathke's pouch An anatomical cavity that surrounded_by a Rathke's pouch. go-plus.json Rathkes pouch invagination http://purl.obolibrary.org/obo/UBERON_0009974 GO:0005802 biolink:CellularComponent trans-Golgi network The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. NIF_Subcellular:sao9456487 go-plus.json Golgi trans face|late Golgi|trans Golgi network|TGN|trans face|Golgi trans-face|maturing face http://purl.obolibrary.org/obo/GO_0005802 CHEBI:17360 biolink:ChemicalSubstance D-altronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17360 chebi_ph7_3 GO:0005803 biolink:CellularComponent obsolete secretory vesicle OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. go-plus.json secretory vesicle|transition vesicle http://purl.obolibrary.org/obo/GO_0005803 GO:0005800 biolink:CellularComponent obsolete COPII vesicle OBSOLETE. (Was not defined before being made obsolete). go-plus.json COPII vesicle http://purl.obolibrary.org/obo/GO_0005800 GO:0005801 biolink:CellularComponent cis-Golgi network The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum. NIF_Subcellular:sao632188024 go-plus.json Golgi cis face|cis Golgi network|cis face|forming face|Golgi cis-face http://purl.obolibrary.org/obo/GO_0005801 CHEBI:32975 biolink:ChemicalSubstance (R)-2,3,4,5-tetrahydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32975 CHEBI:32976 biolink:ChemicalSubstance 2,3,4,5-tetrahydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32976 CHEBI:32978 biolink:ChemicalSubstance (R)-3-phenyllactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32978 CHEBI:32979 biolink:ChemicalSubstance (S)-3-phenyllactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32979 chebi_ph7_3 CHEBI:32970 biolink:ChemicalSubstance 2-aminoethanesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32970 CHEBI:32971 biolink:ChemicalSubstance 3,4,6-trichlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_32971 CHEBI:17358 biolink:ChemicalSubstance N(4)-phosphoagmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17358 CHEBI:17359 biolink:ChemicalSubstance sulfite go-plus.json http://purl.obolibrary.org/obo/CHEBI_17359 chebi_ph7_3 CHEBI:17356 biolink:ChemicalSubstance 2-acetamidofluorene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17356 chebi_ph7_3 CHEBI:17357 biolink:ChemicalSubstance L-rhamnonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17357 UBERON:0010948 biolink:AnatomicalEntity cleidooccipital muscle A muscle organ that attaches_to a clavicle and attaches_to a occipital bone. go-plus.json cleidooccipital|cleido-occipitalis muscle|cleido-occipitalis http://purl.obolibrary.org/obo/UBERON_0010948 GO:0005808 biolink:CellularComponent obsolete Golgi-plasma membrane transport vesicle OBSOLETE. (Was not defined before being made obsolete). go-plus.json Golgi-plasma membrane transport vesicle http://purl.obolibrary.org/obo/GO_0005808 CHEBI:17354 biolink:ChemicalSubstance 16beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17354 chebi_ph7_3 UBERON:0010949 biolink:AnatomicalEntity sternooccipital muscle A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum. go-plus.json sternooccipital http://purl.obolibrary.org/obo/UBERON_0010949 GO:0005809 biolink:CellularComponent obsolete Golgi-vacuole transport vesicle OBSOLETE. (Was not defined before being made obsolete). go-plus.json Golgi-vacuole transport vesicle http://purl.obolibrary.org/obo/GO_0005809 CHEBI:17355 biolink:ChemicalSubstance (S)-2-acetamido-6-oxopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17355 GO:0005806 biolink:CellularComponent obsolete Golgi-ER transport vesicle OBSOLETE. (Was not defined before being made obsolete). go-plus.json Golgi-ER transport vesicle http://purl.obolibrary.org/obo/GO_0005806 CHEBI:17352 biolink:ChemicalSubstance (R)-mandelamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17352 chebi_ph7_3 GO:0005807 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005807 GO:0005804 biolink:CellularComponent obsolete secretory vesicle membrane OBSOLETE. (Was not defined before being made obsolete). go-plus.json secretory vesicle membrane http://purl.obolibrary.org/obo/GO_0005804 CHEBI:17351 biolink:ChemicalSubstance linoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17351 GO:0005805 biolink:CellularComponent obsolete ER-Golgi transport vesicle OBSOLETE. (Was not defined before being made obsolete). go-plus.json ER-Golgi transport vesicle http://purl.obolibrary.org/obo/GO_0005805 GO:0030899 biolink:MolecularActivity calcium-dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+). go-plus.json http://purl.obolibrary.org/obo/GO_0030899 GO:0030897 biolink:CellularComponent HOPS complex A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0030897 GO:0030898 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030898 GO:0030895 biolink:CellularComponent apolipoprotein B mRNA editing enzyme complex Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP). go-plus.json apoB mRNA editing enzyme complex|APOBEC http://purl.obolibrary.org/obo/GO_0030895 GO:0030896 biolink:CellularComponent checkpoint clamp complex Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage. go-plus.json Rad9-Hus1-Rad1 (9-1-1) clamp complex|CCC http://purl.obolibrary.org/obo/GO_0030896 GO:0015256 biolink:MolecularActivity obsolete monocarboxylate channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json monocarboxylate channel activity http://purl.obolibrary.org/obo/GO_0015256 GO:0015257 biolink:MolecularActivity obsolete organic anion channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json organic anion channel activity http://purl.obolibrary.org/obo/GO_0015257 GO:0015258 biolink:MolecularActivity obsolete gluconate channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json gluconate channel activity http://purl.obolibrary.org/obo/GO_0015258 GO:0015259 biolink:MolecularActivity obsolete glutamate channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json glutamate channel activity http://purl.obolibrary.org/obo/GO_0015259 GO:0030893 biolink:CellularComponent meiotic cohesin complex A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0030893 GO:0015252 biolink:MolecularActivity proton channel activity Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. go-plus.json hydrogen ion channel activity http://purl.obolibrary.org/obo/GO_0015252 GO:0030894 biolink:CellularComponent replisome A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. Wikipedia:Replisome go-plus.json replication-competent complex|DNA synthesome complex|RC complex http://purl.obolibrary.org/obo/GO_0030894 goslim_pir GO:0015253 biolink:MolecularActivity obsolete sugar/polyol channel activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json sugar/polyol channel activity http://purl.obolibrary.org/obo/GO_0015253 GO:0030891 biolink:CellularComponent VCB complex A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1. go-plus.json VHL complex|von Hippel-Lindau tumor suppressor complex|pVHL-elongin C-elongin B complex http://purl.obolibrary.org/obo/GO_0030891 GO:0015254 biolink:MolecularActivity glycerol channel activity Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-507871|Reactome:R-HSA-432074|Reactome:R-HSA-432049|RHEA:29675|Reactome:R-HSA-507869 go-plus.json http://purl.obolibrary.org/obo/GO_0015254 GO:0030892 biolink:CellularComponent mitotic cohesin complex A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0030892 GO:0015255 biolink:MolecularActivity propanediol channel activity Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0015255 GO:0030890 biolink:BiologicalProcess positive regulation of B cell proliferation Any process that activates or increases the rate or extent of B cell proliferation. go-plus.json positive regulation of B-lymphocyte proliferation|up regulation of B cell proliferation|positive regulation of B lymphocyte proliferation|upregulation of B cell proliferation|stimulation of B cell proliferation|positive regulation of B-cell proliferation|activation of B cell proliferation|up-regulation of B cell proliferation http://purl.obolibrary.org/obo/GO_0030890 GO:0015250 biolink:MolecularActivity water channel activity Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-445714|Reactome:R-HSA-432065|Reactome:R-HSA-432067|Reactome:R-HSA-507868|RHEA:29667|Reactome:R-HSA-432054|Reactome:R-HSA-432010|Reactome:R-HSA-507870 go-plus.json aquaporin http://purl.obolibrary.org/obo/GO_0015250 GO:0015251 biolink:MolecularActivity ammonium channel activity Enables the facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0015251 GO:0030888 biolink:BiologicalProcess regulation of B cell proliferation Any process that modulates the frequency, rate or extent of B cell proliferation. go-plus.json regulation of B lymphocyte proliferation|regulation of B-cell proliferation|regulation of B-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0030888 GO:0030889 biolink:BiologicalProcess negative regulation of B cell proliferation Any process that stops, prevents or reduces the rate or extent of B cell proliferation. go-plus.json downregulation of B cell proliferation|down regulation of B cell proliferation|inhibition of B cell proliferation|negative regulation of B-cell proliferation|negative regulation of B-lymphocyte proliferation|down-regulation of B cell proliferation|negative regulation of B lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0030889 GO:0030886 biolink:BiologicalProcess negative regulation of myeloid dendritic cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. go-plus.json down regulation of myeloid dendritic cell activation|downregulation of myeloid dendritic cell activation|down-regulation of myeloid dendritic cell activation|inhibition of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030886 GO:0030887 biolink:BiologicalProcess positive regulation of myeloid dendritic cell activation Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. go-plus.json upregulation of myeloid dendritic cell activation|up regulation of myeloid dendritic cell activation|activation of myeloid dendritic cell activation|stimulation of myeloid dendritic cell activation|up-regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030887 GO:0030884 biolink:MolecularActivity exogenous lipid antigen binding Binding to an exogenous lipid antigen (examples include microbial lipids and glycolipids). go-plus.json http://purl.obolibrary.org/obo/GO_0030884 GO:0030885 biolink:BiologicalProcess regulation of myeloid dendritic cell activation Any process that modulates the frequency or rate of myeloid dendritic cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_0030885 GO:0015267 biolink:MolecularActivity channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. TC:1|Reactome:R-HSA-3779381|Reactome:R-HSA-8953430 go-plus.json channel/pore class transporter activity|alpha-type channel activity|nonselective channel activity|channel-forming toxin activity|pore activity|pore class transporter activity|substrate-specific channel activity http://purl.obolibrary.org/obo/GO_0015267 GO:0015268 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015268 GO:0015269 biolink:MolecularActivity calcium-activated potassium channel activity Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0015269 GO:0015263 biolink:MolecularActivity obsolete amine/amide/polyamine channel activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json amine/amide/polyamine channel activity http://purl.obolibrary.org/obo/GO_0015263 GO:0030882 biolink:MolecularActivity lipid antigen binding Binding to a lipid antigen. go-plus.json http://purl.obolibrary.org/obo/GO_0030882 GO:0015264 biolink:MolecularActivity methylammonium channel activity Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2. go-plus.json http://purl.obolibrary.org/obo/GO_0015264 GO:0030883 biolink:MolecularActivity endogenous lipid antigen binding Binding to an endogenous cellular lipid antigen. go-plus.json http://purl.obolibrary.org/obo/GO_0030883 GO:0015265 biolink:MolecularActivity urea channel activity Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-507875|Reactome:R-HSA-507873 go-plus.json http://purl.obolibrary.org/obo/GO_0015265 GO:0030880 biolink:CellularComponent RNA polymerase complex Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits. go-plus.json multisubunit RNA polymerase http://purl.obolibrary.org/obo/GO_0030880 goslim_pir GO:0015266 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015266 GO:0030881 biolink:MolecularActivity beta-2-microglobulin binding Binding to beta-2-microglobulin. go-plus.json http://purl.obolibrary.org/obo/GO_0030881 goslim_chembl GO:0015260 biolink:MolecularActivity obsolete isethionate channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json isethionate channel activity http://purl.obolibrary.org/obo/GO_0015260 GO:0015261 biolink:MolecularActivity obsolete lactate channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json lactate channel activity http://purl.obolibrary.org/obo/GO_0015261 GO:0015262 biolink:MolecularActivity obsolete taurine channel activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json taurine channel activity http://purl.obolibrary.org/obo/GO_0015262 GO:0030879 biolink:BiologicalProcess mammary gland development The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. go-plus.json mammogenesis http://purl.obolibrary.org/obo/GO_0030879 GO:0030877 biolink:CellularComponent beta-catenin destruction complex A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. go-plus.json APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex|beta-catenin degradation complex|23S APC complex|BDC http://purl.obolibrary.org/obo/GO_0030877 GO:0030878 biolink:BiologicalProcess thyroid gland development The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0030878 GO:0030875 biolink:CellularComponent rDNA protrusion Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining. go-plus.json ribosomal DNA protrusion http://purl.obolibrary.org/obo/GO_0030875 GO:0030876 biolink:CellularComponent interleukin-20 receptor complex A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits. go-plus.json IL-20 receptor complex http://purl.obolibrary.org/obo/GO_0030876 GO:0030873 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030873 GO:0030874 biolink:CellularComponent nucleolar chromatin The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0030874 GO:0015238 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015238 GO:0015239 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015239 GO:0015234 biolink:MolecularActivity thiamine transmembrane transporter activity Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. RHEA:34919|Reactome:R-HSA-199626 go-plus.json vitamin B1 transporter activity|thiamin uptake transporter activity|thiamin transmembrane transporter activity|thiamin permease activity|thiamine uptake transmembrane transporter activity|thiamine permease activity http://purl.obolibrary.org/obo/GO_0015234 GO:0015235 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015235 GO:0015236 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015236 GO:0015237 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015237 GO:0015230 biolink:MolecularActivity FAD transmembrane transporter activity Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. go-plus.json flavin adenine dinucleotide carrier activity|flavin-adenine dinucleotide transmembrane transporter activity|FAD carrier activity|FAD transporter activity|flavin-adenine dinucleotide carrier activity|flavin adenine dinucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015230 GO:0030871 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030871 GO:0015231 biolink:MolecularActivity 5-formyltetrahydrofolate transmembrane transporter activity Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other. go-plus.json 5-formyltetrahydrofolate transporter activity http://purl.obolibrary.org/obo/GO_0015231 GO:0030872 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030872 GO:0015232 biolink:MolecularActivity heme transmembrane transporter activity Enables the transfer of heme from one side of a membrane to the other. Reactome:R-HSA-917870|Reactome:R-HSA-9661408|Reactome:R-HSA-917892 go-plus.json heme transporter activity|haem transporter activity http://purl.obolibrary.org/obo/GO_0015232 GO:0030870 biolink:CellularComponent Mre11 complex Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. go-plus.json RAD50-MRE11-NBN complex|RMX complex|MRX complex|Rad50 complex|MRN complex|Rad50-Rad32-Nbs1 complex http://purl.obolibrary.org/obo/GO_0030870 GO:0015233 biolink:MolecularActivity pantothenate transmembrane transporter activity Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. go-plus.json pantothenate transporter activity|vitamin B5 transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015233 GO:0030868 biolink:CellularComponent smooth endoplasmic reticulum membrane The lipid bilayer surrounding the smooth endoplasmic reticulum. NIF_Subcellular:sao1596955044 go-plus.json smooth ER membrane|SER membrane http://purl.obolibrary.org/obo/GO_0030868 GO:0030869 biolink:CellularComponent RENT complex A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0030869 GO:0030866 biolink:BiologicalProcess cortical actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. go-plus.json cortical actin cytoskeleton organisation|cortical actin cytoskeleton organization and biogenesis|cortical resistance|cortical actin cytoskeleton stabilization|actin cortex stabilization http://purl.obolibrary.org/obo/GO_0030866 GO:0030867 biolink:CellularComponent rough endoplasmic reticulum membrane The lipid bilayer surrounding the rough endoplasmic reticulum. NIF_Subcellular:sao3089754107 go-plus.json rough ER membrane|RER membrane http://purl.obolibrary.org/obo/GO_0030867 GO:0030864 biolink:CellularComponent cortical actin cytoskeleton The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0030864 GO:0030865 biolink:BiologicalProcess cortical cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. go-plus.json cortical cytoskeleton organization and biogenesis|cortical cytoskeleton organisation http://purl.obolibrary.org/obo/GO_0030865 GO:0030862 biolink:BiologicalProcess positive regulation of polarized epithelial cell differentiation Any process that activates or increases the rate or extent of polarized epithelial cell differentiation. go-plus.json up regulation of polarized epithelial cell differentiation|activation of polarized epithelial cell differentiation|stimulation of polarized epithelial cell differentiation|up-regulation of polarized epithelial cell differentiation|upregulation of polarized epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030862 GO:0030863 biolink:CellularComponent cortical cytoskeleton The portion of the cytoskeleton that lies just beneath the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0030863 GO:0015249 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015249 GO:0015245 biolink:MolecularActivity fatty acid transmembrane transporter activity Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. Reactome:R-HSA-879585|Reactome:R-HSA-5627891 go-plus.json fatty acyl transporter activity|peroxisomal fatty acyl transporter|fatty acid transporter activity|fatty-acyl group transporter activity http://purl.obolibrary.org/obo/GO_0015245 GO:0015246 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015246 GO:0015247 biolink:MolecularActivity aminophospholipid flippase activity Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group. go-plus.json aminophospholipid transmembrane transporter activity|aminophospholipid transporter activity http://purl.obolibrary.org/obo/GO_0015247 GO:0015248 biolink:MolecularActivity sterol transporter activity Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. Reactome:R-HSA-8867667|Reactome:R-HSA-5250531|Reactome:R-HSA-8868402|Reactome:R-HSA-5679101|Reactome:R-HSA-265783|Reactome:R-HSA-5679145|RHEA:39747 go-plus.json http://purl.obolibrary.org/obo/GO_0015248 GO:0030860 biolink:BiologicalProcess regulation of polarized epithelial cell differentiation Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0030860 GO:0015241 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015241 GO:0030861 biolink:BiologicalProcess negative regulation of polarized epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation. go-plus.json downregulation of polarized epithelial cell differentiation|down-regulation of polarized epithelial cell differentiation|inhibition of polarized epithelial cell differentiation|down regulation of polarized epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030861 GO:0015242 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015242 GO:0015243 biolink:MolecularActivity cycloheximide transmembrane transporter activity Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes. go-plus.json cycloheximide transporter activity http://purl.obolibrary.org/obo/GO_0015243 GO:0015244 biolink:MolecularActivity fluconazole transmembrane transporter activity Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections. go-plus.json fluconazole transporter activity http://purl.obolibrary.org/obo/GO_0015244 GO:0015240 biolink:MolecularActivity amiloride transmembrane transporter activity Enables the transfer of amiloride from one side of a membrane to the other. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic. go-plus.json amiloride transporter activity http://purl.obolibrary.org/obo/GO_0015240 GO:0030857 biolink:BiologicalProcess negative regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. go-plus.json downregulation of epithelial cell differentiation|down-regulation of epithelial cell differentiation|inhibition of epithelial cell differentiation|down regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030857 GO:0030858 biolink:BiologicalProcess positive regulation of epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. go-plus.json up regulation of epithelial cell differentiation|activation of epithelial cell differentiation|stimulation of epithelial cell differentiation|up-regulation of epithelial cell differentiation|upregulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030858 GO:0005899 biolink:CellularComponent insulin receptor complex A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain. go-plus.json http://purl.obolibrary.org/obo/GO_0005899 GO:0030855 biolink:BiologicalProcess epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0030855 GO:0030856 biolink:BiologicalProcess regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0030856 GO:0005897 biolink:CellularComponent interleukin-9 receptor complex A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins. go-plus.json IL-9 receptor complex http://purl.obolibrary.org/obo/GO_0005897 GO:0030853 biolink:BiologicalProcess negative regulation of granulocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation. go-plus.json downregulation of granulocyte differentiation|down-regulation of granulocyte differentiation|inhibition of granulocyte differentiation|down regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030853 GO:0005898 biolink:CellularComponent interleukin-13 receptor complex A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain. go-plus.json IL-13 receptor complex http://purl.obolibrary.org/obo/GO_0005898 GO:0030854 biolink:BiologicalProcess positive regulation of granulocyte differentiation Any process that activates or increases the frequency, rate or extent of granulocyte differentiation. go-plus.json up regulation of granulocyte differentiation|activation of granulocyte differentiation|stimulation of granulocyte differentiation|up-regulation of granulocyte differentiation|upregulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030854 GO:0005895 biolink:CellularComponent interleukin-5 receptor complex A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3. go-plus.json IL-5 receptor complex http://purl.obolibrary.org/obo/GO_0005895 GO:0030851 biolink:BiologicalProcess granulocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils. go-plus.json granulocyte cell differentiation http://purl.obolibrary.org/obo/GO_0030851 GO:0030852 biolink:BiologicalProcess regulation of granulocyte differentiation Any process that modulates the frequency, rate or extent of granulocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0030852 GO:0005896 biolink:CellularComponent interleukin-6 receptor complex A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130. go-plus.json IL-6 receptor complex http://purl.obolibrary.org/obo/GO_0005896 GO:0005893 biolink:CellularComponent interleukin-2 receptor complex A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits. go-plus.json IL-2 receptor complex http://purl.obolibrary.org/obo/GO_0005893 UBERON:0009906 biolink:AnatomicalEntity root of optic nerve A nerve root that extends_fibers_into a nerve connecting eye with brain. go-plus.json optic nerve root|optic tract root|root of optic tract http://purl.obolibrary.org/obo/UBERON_0009906 GO:0005894 biolink:CellularComponent interleukin-3 receptor complex A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5. go-plus.json IL-3 receptor complex http://purl.obolibrary.org/obo/GO_0005894 GO:0005891 biolink:CellularComponent voltage-gated calcium channel complex A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. go-plus.json voltage-sensitive calcium channel complex|voltage gated calcium channel complex|voltage-dependent calcium channel complex http://purl.obolibrary.org/obo/GO_0005891 goslim_pir GO:0005892 biolink:CellularComponent acetylcholine-gated channel complex A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding. go-plus.json nicotinic acetylcholine receptor|nicotinic acetylcholine-gated receptor-channel complex http://purl.obolibrary.org/obo/GO_0005892 GO:0005890 biolink:CellularComponent sodium:potassium-exchanging ATPase complex Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior. go-plus.json sodium pump|sodium/potassium-exchanging ATPase complex http://purl.obolibrary.org/obo/GO_0005890 GO:0030859 biolink:BiologicalProcess polarized epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis. go-plus.json http://purl.obolibrary.org/obo/GO_0030859 CHEBI:42394 biolink:ChemicalSubstance tricosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42394 GO:0015216 biolink:MolecularActivity purine nucleotide transmembrane transporter activity Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015216 GO:0015217 biolink:MolecularActivity ADP transmembrane transporter activity Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015217 GO:0015218 biolink:MolecularActivity pyrimidine nucleotide transmembrane transporter activity Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015218 UBERON:0009911 biolink:AnatomicalEntity lobule go-plus.json lobulus http://purl.obolibrary.org/obo/UBERON_0009911 UBERON:0009912 biolink:AnatomicalEntity anatomical lobe A portion of an organ, such as the liver, lung, breast, or brain. go-plus.json lobus http://purl.obolibrary.org/obo/UBERON_0009912 GO:0015219 biolink:MolecularActivity obsolete protein-DNA complex transmembrane transporter activity OBSOLETE. Enables the transfer of protein-DNA complexes from one side of a membrane to the other. go-plus.json DNA-protein complex transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015219 UBERON:0009913 biolink:AnatomicalEntity renal lobe The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]. go-plus.json lobi renalis|lobi renales|lobus renalis|kidney lobe http://purl.obolibrary.org/obo/UBERON_0009913 GO:0015212 biolink:MolecularActivity cytidine transmembrane transporter activity Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015212 UBERON:0009914 biolink:AnatomicalEntity renal lobule The portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys go-plus.json renunculus|renal cortical lobule|cortical lobule of kidney|renculus|cortical lobule|lobulus corticalis renalis|kidney lobule|lobuli corticales renis|reniculus|lobulus renalis http://purl.obolibrary.org/obo/UBERON_0009914 GO:0015213 biolink:MolecularActivity uridine transmembrane transporter activity Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other. go-plus.json uracil/uridine permease activity http://purl.obolibrary.org/obo/GO_0015213 GO:0015214 biolink:MolecularActivity pyrimidine nucleoside transmembrane transporter activity Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015214 UBERON:0009916 biolink:AnatomicalEntity wall of ureter An anatomical wall that is part of a ureter. go-plus.json ureteral wall http://purl.obolibrary.org/obo/UBERON_0009916 GO:0015215 biolink:MolecularActivity nucleotide transmembrane transporter activity Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015215 GO:0030850 biolink:BiologicalProcess prostate gland development The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. go-plus.json prostate development http://purl.obolibrary.org/obo/GO_0030850 GO:0015210 biolink:MolecularActivity uracil transmembrane transporter activity Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other. go-plus.json uracil/uridine permease activity http://purl.obolibrary.org/obo/GO_0015210 GO:0015211 biolink:MolecularActivity purine nucleoside transmembrane transporter activity Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015211 GO:0030846 biolink:BiologicalProcess termination of RNA polymerase II transcription, poly(A)-coupled The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination. go-plus.json transcription termination from Pol II promoter, RNA polymerase(A) coupled|termination of RNA polymerase II transcription, polyadenylation-coupled|transcription termination from Pol II promoter, poly(A) coupled http://purl.obolibrary.org/obo/GO_0030846 GO:0030847 biolink:BiologicalProcess termination of RNA polymerase II transcription, exosome-dependent The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end. go-plus.json transcription termination from Pol II promoter, poly(A)-independent|termination of RNA polymerase II transcription, poly(A)-independent|transcription termination from Pol II promoter, RNA polymerase(A)-independent http://purl.obolibrary.org/obo/GO_0030847 GO:0030844 biolink:BiologicalProcess positive regulation of intermediate filament depolymerization Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization. go-plus.json upregulation of intermediate filament depolymerization|positive regulation of intermediate filament polymerization and/or depolymerization|stimulation of intermediate filament depolymerization|up-regulation of intermediate filament depolymerization|activation of intermediate filament depolymerization|up regulation of intermediate filament depolymerization http://purl.obolibrary.org/obo/GO_0030844 GO:0030845 biolink:BiologicalProcess phospholipase C-inhibiting G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json phospholipase C inhibition|inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway|G-protein-coupled inhibitory pathway of phospholipase C|GPCR signaling pathway via inhibition of PLC|GPCR signaling pathway coupled to inhibition of phospholipase C activity|phospholipase C-inhibiting G-protein coupled receptor signaling pathway|PLC-inhibiting GPCR signaling pathway http://purl.obolibrary.org/obo/GO_0030845 GO:0030842 biolink:BiologicalProcess regulation of intermediate filament depolymerization Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament. go-plus.json http://purl.obolibrary.org/obo/GO_0030842 GO:0030843 biolink:BiologicalProcess negative regulation of intermediate filament depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization. go-plus.json inhibition of intermediate filament depolymerization|negative regulation of intermediate filament polymerization and/or depolymerization|down-regulation of intermediate filament depolymerization|downregulation of intermediate filament depolymerization|down regulation of intermediate filament depolymerization http://purl.obolibrary.org/obo/GO_0030843 GO:0030840 biolink:BiologicalProcess negative regulation of intermediate filament polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization. go-plus.json inhibition of intermediate filament polymerization|negative regulation of intermediate filament polymerization and/or depolymerization|down-regulation of intermediate filament polymerization|downregulation of intermediate filament polymerization|down regulation of intermediate filament polymerization http://purl.obolibrary.org/obo/GO_0030840 GO:0030841 biolink:BiologicalProcess positive regulation of intermediate filament polymerization Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization. go-plus.json upregulation of intermediate filament polymerization|positive regulation of intermediate filament polymerization and/or depolymerization|stimulation of intermediate filament polymerization|activation of intermediate filament polymerization|up-regulation of intermediate filament polymerization|up regulation of intermediate filament polymerization http://purl.obolibrary.org/obo/GO_0030841 GO:0030848 biolink:MolecularActivity threo-3-hydroxyaspartate ammonia-lyase activity Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate. MetaCyc:4.3.1.16-RXN|EC:4.3.1.16|KEGG_REACTION:R05758|RHEA:12424 go-plus.json threo-3-hydroxy-L-aspartate ammonia-lyase activity|threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)|3-hydroxyaspartate dehydratase activity|threo-3-hydroxyaspartate dehydratase activity|L-threo-3-hydroxyaspartate dehydratase activity http://purl.obolibrary.org/obo/GO_0030848 GO:0030849 biolink:CellularComponent autosome Any chromosome other than a sex chromosome. Wikipedia:Autosome go-plus.json http://purl.obolibrary.org/obo/GO_0030849 GO:0015227 biolink:MolecularActivity acyl carnitine transmembrane transporter activity Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane. Reactome:R-HSA-200424 go-plus.json acylcarnitine transporter activity http://purl.obolibrary.org/obo/GO_0015227 GO:0015228 biolink:MolecularActivity coenzyme A transmembrane transporter activity Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. go-plus.json coenzyme A transporter activity http://purl.obolibrary.org/obo/GO_0015228 GO:0015229 biolink:MolecularActivity L-ascorbic acid transmembrane transporter activity Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species. Reactome:R-HSA-198870 go-plus.json vitamin C transporter activity|L-ascorbate transporter activity http://purl.obolibrary.org/obo/GO_0015229 GO:0015223 biolink:MolecularActivity obsolete vitamin or cofactor transporter activity OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells. go-plus.json vitamin/cofactor transporter activity|vitamin or cofactor transporter activity http://purl.obolibrary.org/obo/GO_0015223 GO:0015224 biolink:MolecularActivity biopterin transmembrane transporter activity Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme. go-plus.json biopterin transporter activity http://purl.obolibrary.org/obo/GO_0015224 GO:0015225 biolink:MolecularActivity biotin transmembrane transporter activity Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. RHEA:28458 go-plus.json biotin transporter activity|vitamin H transporter activity|vitamin B7 transporter activity http://purl.obolibrary.org/obo/GO_0015225 GO:0015226 biolink:MolecularActivity carnitine transmembrane transporter activity Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. Reactome:R-HSA-549297|Reactome:R-HSA-164967|Reactome:R-HSA-5625674|Reactome:R-HSA-165026 go-plus.json vitamin Bt transporter activity http://purl.obolibrary.org/obo/GO_0015226 GO:0015220 biolink:MolecularActivity choline transmembrane transporter activity Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. Reactome:R-HSA-444433|Reactome:R-HSA-6797956|Reactome:R-HSA-5658483|Reactome:R-HSA-429594 go-plus.json amino acid/choline transmembrane transporter activity|choline permease activity http://purl.obolibrary.org/obo/GO_0015220 GO:0015221 biolink:MolecularActivity lipopolysaccharide transmembrane transporter activity Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. go-plus.json LPS transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015221 GO:0015222 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015222 GO:0030835 biolink:BiologicalProcess negative regulation of actin filament depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization. go-plus.json down-regulation of actin filament depolymerization|inhibition of actin filament depolymerization|negative regulation of actin polymerization and/or depolymerization|down regulation of actin filament depolymerization|downregulation of actin filament depolymerization|actin filament stabilization|negative regulation of actin depolymerization http://purl.obolibrary.org/obo/GO_0030835 GO:0005879 biolink:CellularComponent axonemal microtubule A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0005879 GO:0030836 biolink:BiologicalProcess positive regulation of actin filament depolymerization Any process that activates or increases the frequency, rate or extent of actin depolymerization. go-plus.json actin filament destabilization|stimulation of actin filament depolymerization|positive regulation of actin depolymerization|up-regulation of actin filament depolymerization|positive regulation of actin polymerization and/or depolymerization|upregulation of actin filament depolymerization|up regulation of actin filament depolymerization|activation of actin filament depolymerization http://purl.obolibrary.org/obo/GO_0030836 GO:0030833 biolink:BiologicalProcess regulation of actin filament polymerization Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament. go-plus.json regulation of actin polymerization http://purl.obolibrary.org/obo/GO_0030833 GO:0030834 biolink:BiologicalProcess regulation of actin filament depolymerization Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament. go-plus.json regulation of actin depolymerization http://purl.obolibrary.org/obo/GO_0030834 GO:0030831 biolink:BiologicalProcess obsolete positive regulation of cGMP catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP. go-plus.json upregulation of cGMP catabolic process|positive regulation of cGMP catabolism|stimulation of cGMP catabolic process|up-regulation of cGMP catabolic process|activation of cGMP catabolic process|positive regulation of cGMP degradation|positive regulation of cGMP breakdown|up regulation of cGMP catabolic process http://purl.obolibrary.org/obo/GO_0030831 GO:0005875 biolink:CellularComponent microtubule associated complex Any multimeric complex connected to a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0005875 GO:0005876 biolink:CellularComponent spindle microtubule Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. go-plus.json http://purl.obolibrary.org/obo/GO_0005876 GO:0030832 biolink:BiologicalProcess regulation of actin filament length Any process that controls the length of actin filaments in a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030832 GO:0005873 biolink:CellularComponent plus-end kinesin complex Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0005873 GO:0005874 biolink:CellularComponent microtubule Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. Wikipedia:Microtubule|NIF_Subcellular:sao1846835077 go-plus.json neurotubule|microtubuli|microtubulus http://purl.obolibrary.org/obo/GO_0005874 goslim_metagenomics GO:0030830 biolink:BiologicalProcess obsolete negative regulation of cGMP catabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP. go-plus.json downregulation of cGMP catabolic process|down regulation of cGMP catabolic process|inhibition of cGMP catabolic process|negative regulation of cGMP degradation|negative regulation of cGMP catabolism|negative regulation of cGMP breakdown|down-regulation of cGMP catabolic process http://purl.obolibrary.org/obo/GO_0030830 GO:0005871 biolink:CellularComponent kinesin complex Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work. go-plus.json http://purl.obolibrary.org/obo/GO_0005871 GO:0005872 biolink:CellularComponent minus-end kinesin complex Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0005872 GO:0005870 biolink:CellularComponent actin capping protein of dynactin complex A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0005870 GO:0030839 biolink:BiologicalProcess regulation of intermediate filament polymerization Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament. go-plus.json http://purl.obolibrary.org/obo/GO_0030839 GO:0030837 biolink:BiologicalProcess negative regulation of actin filament polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization. go-plus.json negative regulation of actin polymerization|down-regulation of actin filament polymerization|inhibition of actin filament polymerization|negative regulation of actin polymerization and/or depolymerization|down regulation of actin filament polymerization|downregulation of actin filament polymerization http://purl.obolibrary.org/obo/GO_0030837 GO:0030838 biolink:BiologicalProcess positive regulation of actin filament polymerization Any process that activates or increases the frequency, rate or extent of actin polymerization. go-plus.json activation of actin filament polymerization|stimulation of actin filament polymerization|positive regulation of actin polymerization|up-regulation of actin filament polymerization|positive regulation of actin polymerization and/or depolymerization|upregulation of actin filament polymerization|up regulation of actin filament polymerization http://purl.obolibrary.org/obo/GO_0030838 GO:0030824 biolink:BiologicalProcess obsolete negative regulation of cGMP metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP. go-plus.json down-regulation of cGMP metabolic process|negative regulation of cGMP metabolism|downregulation of cGMP metabolic process|down regulation of cGMP metabolic process|inhibition of cGMP metabolic process http://purl.obolibrary.org/obo/GO_0030824 GO:0030825 biolink:BiologicalProcess obsolete positive regulation of cGMP metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP. go-plus.json activation of cGMP metabolic process|positive regulation of cGMP metabolism|up regulation of cGMP metabolic process|upregulation of cGMP metabolic process|stimulation of cGMP metabolic process|up-regulation of cGMP metabolic process http://purl.obolibrary.org/obo/GO_0030825 GO:0030822 biolink:BiologicalProcess obsolete positive regulation of cAMP catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json upregulation of cAMP catabolic process|stimulation of cAMP catabolic process|up-regulation of cAMP catabolic process|activation of cAMP catabolic process|positive regulation of cAMP degradation|positive regulation of 3',5' cAMP catabolism|positive regulation of cAMP breakdown|positive regulation of 3',5'-cAMP catabolic process|positive regulation of cyclic AMP catabolism|positive regulation of adenosine 3',5'-cyclophosphate catabolic process|up regulation of cAMP catabolic process|positive regulation of cAMP catabolism|positive regulation of adenosine 3',5'-cyclophosphate catabolism|positive regulation of cyclic AMP catabolic process|positive regulation of 3',5'-cAMP catabolism|positive regulation of 3',5' cAMP catabolic process http://purl.obolibrary.org/obo/GO_0030822 GO:0005888 biolink:CellularComponent obsolete proteoglycan integral to plasma membrane OBSOLETE. Penetrating at least one phospholipid bilayer of a plasma membrane and consisting of proteoglycan. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer. go-plus.json proteoglycan integral to plasma membrane http://purl.obolibrary.org/obo/GO_0005888 GO:0005889 biolink:CellularComponent potassium:proton exchanging ATPase complex A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present. go-plus.json hydrogen/potassium-exchanging ATPase complex|proton pump|hydrogen:potassium-exchanging ATPase complex http://purl.obolibrary.org/obo/GO_0005889 GO:0030823 biolink:BiologicalProcess obsolete regulation of cGMP metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP. go-plus.json regulation of cGMP metabolism http://purl.obolibrary.org/obo/GO_0030823 GO:0005886 biolink:CellularComponent plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. Wikipedia:Cell_membrane|NIF_Subcellular:sao1663586795 go-plus.json cellular membrane|inner endospore membrane|cell membrane|bacterial inner membrane|cytoplasmic membrane|plasma membrane lipid bilayer|plasmalemma|juxtamembrane http://purl.obolibrary.org/obo/GO_0005886 goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_candida|goslim_yeast|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_aspergillus GO:0030820 biolink:BiologicalProcess obsolete regulation of cAMP catabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json regulation of 3',5' cAMP catabolic process|regulation of 3',5' cAMP catabolism|regulation of cyclic AMP catabolism|regulation of cAMP catabolism|regulation of adenosine 3',5'-cyclophosphate catabolism|regulation of cAMP degradation|regulation of 3',5'-cAMP catabolism|regulation of cAMP breakdown|regulation of 3',5'-cAMP catabolic process|regulation of adenosine 3',5'-cyclophosphate catabolic process|regulation of cyclic AMP catabolic process http://purl.obolibrary.org/obo/GO_0030820 GO:0030821 biolink:BiologicalProcess obsolete negative regulation of cAMP catabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). go-plus.json negative regulation of 3',5'-cAMP catabolism|negative regulation of cAMP degradation|negative regulation of cAMP breakdown|negative regulation of 3',5'-cAMP catabolic process|down-regulation of cAMP catabolic process|negative regulation of adenosine 3',5'-cyclophosphate catabolic process|negative regulation of 3',5' cAMP catabolism|negative regulation of cyclic AMP catabolic process|negative regulation of cyclic AMP catabolism|downregulation of cAMP catabolic process|negative regulation of 3',5' cAMP catabolic process|negative regulation of adenosine 3',5'-cyclophosphate catabolism|negative regulation of cAMP catabolism|down regulation of cAMP catabolic process|inhibition of cAMP catabolic process http://purl.obolibrary.org/obo/GO_0030821 GO:0005887 biolink:CellularComponent integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to plasma membrane http://purl.obolibrary.org/obo/GO_0005887 GO:0005884 biolink:CellularComponent actin filament A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. FMA:63850|Wikipedia:Actin|NIF_Subcellular:sao1588493326 go-plus.json microfilament http://purl.obolibrary.org/obo/GO_0005884 GO:0005885 biolink:CellularComponent Arp2/3 protein complex A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0005885 GO:0005882 biolink:CellularComponent intermediate filament A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. Wikipedia:Intermediate_filament|FMA:63851|NIF_Subcellular:sao952483289 go-plus.json intermediate filament associated protein|type I intermediate filament associated protein|type II intermediate filament associated protein http://purl.obolibrary.org/obo/GO_0005882 GO:0005883 biolink:CellularComponent neurofilament A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. NIF_Subcellular:sao1316272517|Wikipedia:Neurofilament go-plus.json type IV intermediate filament http://purl.obolibrary.org/obo/GO_0005883 GO:0005880 biolink:CellularComponent nuclear microtubule Any microtubule in the nucleus of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0005880 GO:0005881 biolink:CellularComponent cytoplasmic microtubule Any microtubule in the cytoplasm of a cell. go-plus.json non-spindle-associated astral microtubule http://purl.obolibrary.org/obo/GO_0005881 GO:0030828 biolink:BiologicalProcess obsolete positive regulation of cGMP biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP. go-plus.json up regulation of cGMP biosynthetic process|activation of cGMP biosynthetic process|positive regulation of cGMP biosynthesis|stimulation of cGMP biosynthetic process|up-regulation of cGMP biosynthetic process|positive regulation of cGMP anabolism|upregulation of cGMP biosynthetic process|positive regulation of cGMP synthesis|positive regulation of cGMP formation http://purl.obolibrary.org/obo/GO_0030828 GO:0015209 biolink:MolecularActivity cytosine transmembrane transporter activity Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015209 GO:0030829 biolink:BiologicalProcess obsolete regulation of cGMP catabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP. go-plus.json regulation of cGMP degradation|regulation of cGMP breakdown|regulation of cGMP catabolism http://purl.obolibrary.org/obo/GO_0030829 FAO:0002002 biolink:OntologyClass multicellular fungal structure A fungal structure that comprises more than one cell. go-plus.json http://purl.obolibrary.org/obo/FAO_0002002 GO:0030826 biolink:BiologicalProcess obsolete regulation of cGMP biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP. go-plus.json regulation of cGMP synthesis|regulation of cGMP formation|regulation of cGMP anabolism|regulation of cGMP biosynthesis http://purl.obolibrary.org/obo/GO_0030826 GO:0030827 biolink:BiologicalProcess obsolete negative regulation of cGMP biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP. go-plus.json negative regulation of cGMP biosynthesis|down-regulation of cGMP biosynthetic process|inhibition of cGMP biosynthetic process|negative regulation of cGMP anabolism|negative regulation of cGMP synthesis|negative regulation of cGMP formation|down regulation of cGMP biosynthetic process|downregulation of cGMP biosynthetic process http://purl.obolibrary.org/obo/GO_0030827 FAO:0002004 biolink:OntologyClass multicellular fungal structure, multicellular organism A multicellular fungal structure composed of two or more cells of a single multicellular organism. go-plus.json multicellular structure, multicellular organism http://purl.obolibrary.org/obo/FAO_0002004 CHEBI:42362 biolink:ChemicalSubstance (6E,10E)-2,6,10-trimethyldodeca-2,6,10-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_42362 chebi_ph7_3 GO:0015205 biolink:MolecularActivity nucleobase transmembrane transporter activity Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015205 GO:0015206 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015206 GO:0015207 biolink:MolecularActivity adenine transmembrane transporter activity Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other. RHEA:34999|Reactome:R-HSA-5672027|Reactome:R-HSA-163215 go-plus.json http://purl.obolibrary.org/obo/GO_0015207 GO:0015208 biolink:MolecularActivity guanine transmembrane transporter activity Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015208 GO:0015201 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015201 GO:0015202 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015202 GO:0015203 biolink:MolecularActivity polyamine transmembrane transporter activity Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other. go-plus.json amine/amide/polyamine channel activity http://purl.obolibrary.org/obo/GO_0015203 GO:0015204 biolink:MolecularActivity urea transmembrane transporter activity Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2. RHEA:32799|Reactome:R-HSA-444126 go-plus.json urea transporter activity http://purl.obolibrary.org/obo/GO_0015204 GO:0015200 biolink:MolecularActivity methylammonium transmembrane transporter activity Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015200 CHEBI:6331 biolink:ChemicalSubstance erythro-4-hydroxy-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_6331 chebi_ph7_3 OBA:VT0000832 biolink:OntologyClass thalamus morphology trait The morphology of a dorsal plus ventral thalamus. go-plus.json morphology of dorsal plus ventral thalamus http://purl.obolibrary.org/obo/OBA_VT0000832 GO:0015399 biolink:MolecularActivity primary active transmembrane transporter activity Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources. TC:3 go-plus.json primary active transporter http://purl.obolibrary.org/obo/GO_0015399 GO:0015395 biolink:MolecularActivity nucleoside transmembrane transporter activity, down a concentration gradient Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient. go-plus.json equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity|equilibrative nucleoside transporter activity|equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity http://purl.obolibrary.org/obo/GO_0015395 GO:0015396 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015396 GO:0015397 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015397 GO:0015398 biolink:MolecularActivity high-affinity secondary active ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity secondary active ammonium transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015398 GO:0015391 biolink:MolecularActivity nucleobase:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015391 GO:0015392 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015392 GO:0015393 biolink:MolecularActivity obsolete uracil/uridine permease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json uracil/uridine permease activity http://purl.obolibrary.org/obo/GO_0015393 GO:0015394 biolink:MolecularActivity uridine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in). go-plus.json uridine:hydrogen ion symporter activity|nucleoside (uridine) permease activity http://purl.obolibrary.org/obo/GO_0015394 NCBITaxon:330879 biolink:OrganismalEntity Aspergillus fumigatus Af293 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_330879 UBERON:0034994 biolink:AnatomicalEntity hindbrain cortical intermediate zone go-plus.json hindbrain mantle layer http://purl.obolibrary.org/obo/UBERON_0034994 UBERON:0034995 biolink:AnatomicalEntity jaw mesenchyme Mesenchyme that is part of a developing jaw [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034995 UBERON:0034996 biolink:AnatomicalEntity outer renal medulla loop of Henle go-plus.json loop of Henle, outer medullary portion http://purl.obolibrary.org/obo/UBERON_0034996 CHEBI:17309 biolink:ChemicalSubstance pectin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17309 CHEBI:17307 biolink:ChemicalSubstance dTDP-6-deoxy-L-talose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17307 CHEBI:17308 biolink:ChemicalSubstance 2-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17308 CHEBI:17305 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17305 CHEBI:17306 biolink:ChemicalSubstance maltose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17306 chebi_ph7_3 CHEBI:32940 biolink:ChemicalSubstance hexacosane go-plus.json http://purl.obolibrary.org/obo/CHEBI_32940 chebi_ph7_3 CHEBI:17303 biolink:ChemicalSubstance morphine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17303 CHEBI:17304 biolink:ChemicalSubstance piperitenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17304 chebi_ph7_3 CHEBI:17301 biolink:ChemicalSubstance glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17301 CHEBI:17302 biolink:ChemicalSubstance pentadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17302 chebi_ph7_3 CHEBI:17300 biolink:ChemicalSubstance tetrachloroethene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17300 chebi_ph7_3 UBERON:0020358 biolink:AnatomicalEntity accessory XI nerve nucleus The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the ventral horn. The nucleus ambiguus is classically said to provide the 'cranial component' of the accessory nerve. However, the very existence of this cranial component has been recently questioned and seen as contributing exclusively to the vagus nerve. The terminology continues to be used in describing both human anatomy, and that of other animals. go-plus.json nucleus nervi accessorii|nucleus accessorius columnae anterioris medullae spinalis|accessory neural nucleus|nucleus of accessory nerve|accessory nucleus of anterior column of spinal cord|nucleus of the spinal accessory nerve|spinal accessory nucleus|nucleus of the accessory nerve http://purl.obolibrary.org/obo/UBERON_0020358 CHEBI:91230 biolink:ChemicalSubstance 2',2'-dihydroxy-2-oxospirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_91230 chebi_ph7_3 CHEBI:32955 biolink:ChemicalSubstance epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_32955 chebi_ph7_3 CHEBI:32957 biolink:ChemicalSubstance lysophosphatidic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_32957 CHEBI:32958 biolink:ChemicalSubstance phosphate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32958 UBERON:0034997 biolink:AnatomicalEntity renal medulla loop of Henle go-plus.json loop of Henle, medullary portion|loop of Henle of renal medulla http://purl.obolibrary.org/obo/UBERON_0034997 CHEBI:32952 biolink:ChemicalSubstance amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32952 CHEBI:91235 biolink:ChemicalSubstance 19-(4-hydroxyphenyl)nonadecanoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91235 chebi_ph7_3 CHEBI:91236 biolink:ChemicalSubstance 19-(4-hydroxyphenyl)nonadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91236 chebi_ph7_3 CHEBI:91232 biolink:ChemicalSubstance 2-amino-3-hydroxy-4-methylbenzoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91232 chebi_ph7_3 CHEBI:91233 biolink:ChemicalSubstance 17-(4-hydroxyphenyl)heptadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91233 chebi_ph7_3 CHEBI:91234 biolink:ChemicalSubstance 17-(4-hydroxyphenyl)heptadecanoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91234 chebi_ph7_3 NCBITaxon:15368 biolink:OrganismalEntity Brachypodium distachyon go-plus.json stiff brome|false brome|annual false brome|purple false brome http://purl.obolibrary.org/obo/NCBITaxon_15368 CHEBI:32922 biolink:ChemicalSubstance (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_32922 chebi_ph7_3 CHEBI:32926 biolink:ChemicalSubstance octadecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_32926 chebi_ph7_3 CHEBI:17329 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17329 CHEBI:17327 biolink:ChemicalSubstance phytol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17327 chebi_ph7_3 CHEBI:17328 biolink:ChemicalSubstance N(6)-[(indol-3-yl)acetyl]-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17328 CHEBI:17325 biolink:ChemicalSubstance 3-hydroxy-3-methylglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17325 chebi_ph7_3 CHEBI:17326 biolink:ChemicalSubstance nucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17326 CHEBI:17323 biolink:ChemicalSubstance trans-pinosylvin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17323 chebi_ph7_3 CHEBI:91268 biolink:ChemicalSubstance 5-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91268 CHEBI:17321 biolink:ChemicalSubstance 5,6,7,8-tetrahydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17321 CHEBI:17322 biolink:ChemicalSubstance chloric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17322 CHEBI:91264 biolink:ChemicalSubstance 11(R)-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91264 NCBITaxon:15367 biolink:OrganismalEntity Brachypodium go-plus.json false bromes http://purl.obolibrary.org/obo/NCBITaxon_15367 CHEBI:17320 biolink:ChemicalSubstance 23,24-dihydrocucurbitacin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17320 CHEBI:91252 biolink:ChemicalSubstance valienol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91252 chebi_ph7_3 NCBITaxon:207598 biolink:OrganismalEntity Homininae go-plus.json Homo/Pan/Gorilla group http://purl.obolibrary.org/obo/NCBITaxon_207598 UBERON:0010986 biolink:AnatomicalEntity serratus ventralis pre-muscle mass go-plus.json serratus anterior pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0010986 CHEBI:17318 biolink:ChemicalSubstance N-(3,4-dichlorophenyl)malonamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17318 chebi_ph7_3 CHEBI:17319 biolink:ChemicalSubstance 5'-deoxyadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17319 chebi_ph7_3 CHEBI:17316 biolink:ChemicalSubstance 2-N,6-O-disulfo-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17316 CHEBI:17317 biolink:ChemicalSubstance D-sorbose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17317 CHEBI:17314 biolink:ChemicalSubstance 13-hydroxydocosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17314 CHEBI:17315 biolink:ChemicalSubstance D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17315 CHEBI:17312 biolink:ChemicalSubstance N(1)-acetylspermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17312 CHEBI:17313 biolink:ChemicalSubstance 7,8-dihydroxycoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17313 chebi_ph7_3 CHEBI:17310 biolink:ChemicalSubstance pyridoxal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17310 chebi_ph7_3 CHEBI:17311 biolink:ChemicalSubstance N(6),N(6),N(6)-trimethyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17311 CHEBI:91253 biolink:ChemicalSubstance GDP-valienol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91253 chebi_ph7_3 CHEBI:91254 biolink:ChemicalSubstance phosphonoformate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91254 chebi_ph7_3 CHEBI:91255 biolink:ChemicalSubstance CMP-5'-phosphonoformate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91255 chebi_ph7_3 CHEBI:32902 biolink:ChemicalSubstance gibberellin A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_32902 UBERON:0034944 biolink:AnatomicalEntity zone of organ go-plus.json organ zonal region|organ zone|organ sector|organ region with floating fiat boundary http://purl.obolibrary.org/obo/UBERON_0034944 UBERON:0034945 biolink:AnatomicalEntity excreted gas Any gaseous product of an excretory process. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034945 UBERON:0034946 biolink:AnatomicalEntity gas excreted from digestive tract Any excreted gas that is produced by the digestive tract. go-plus.json intestinal gas|flatulence|flatus http://purl.obolibrary.org/obo/UBERON_0034946 UBERON:0034947 biolink:AnatomicalEntity gas in respiratory system Any portion of gas located in a part of the respiratory system. go-plus.json respiratory gas|respiratory system gas http://purl.obolibrary.org/obo/UBERON_0034947 UBERON:0034948 biolink:AnatomicalEntity carbon dioxide in respiratory system Any portion of gas located in a part of the respiratory system that is composed primarily of carbon dioxide. go-plus.json respiratory CO2|respiratory system CO2 http://purl.obolibrary.org/obo/UBERON_0034948 CHEBI:91286 biolink:ChemicalSubstance 5(S),15(S)-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91286 CHEBI:91287 biolink:ChemicalSubstance (5S)-hydroperoxy-18-hydroxy-EPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91287 CHEBI:91271 biolink:ChemicalSubstance 15-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91271 CHEBI:91272 biolink:ChemicalSubstance 13-HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91272 CHEBI:91273 biolink:ChemicalSubstance pyrrolysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_91273 CHEBI:91274 biolink:ChemicalSubstance (7Z,10Z,13R,14E,16Z,19Z)-13-hydroxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_91274 UBERON:0034953 biolink:AnatomicalEntity embryonic lymph sac A population of lymphatic endothelial cell precursors that will form the lymph vessels. go-plus.json primary lymph sac http://purl.obolibrary.org/obo/UBERON_0034953 UBERON:0034969 biolink:AnatomicalEntity epithelial layer of duct go-plus.json duct epithelium|ductal epithelium http://purl.obolibrary.org/obo/UBERON_0034969 CHEBI:91293 biolink:ChemicalSubstance 14-oxo-DoHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_91293 CHEBI:91294 biolink:ChemicalSubstance 12,18-dihydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91294 chebi_ph7_3 CHEBI:91295 biolink:ChemicalSubstance ricinoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_91295 chebi_ph7_3 CHEBI:91296 biolink:ChemicalSubstance lysophosphatidylethanolamine 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_91296 CHEBI:305790 biolink:ChemicalSubstance thyroxine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_305790 chebi_ph7_3 CHEBI:91291 biolink:ChemicalSubstance bacteriochlorophyllide g go-plus.json http://purl.obolibrary.org/obo/CHEBI_91291 CHEBI:91292 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1<->1')-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_91292 CHEBI:91297 biolink:ChemicalSubstance lysophosphatidylcholine(0:0/16:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91297 chebi_ph7_3 CHEBI:91299 biolink:ChemicalSubstance lysophosphatidylcholine(0:0/18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_91299 chebi_ph7_3 GO:0005978 biolink:BiologicalProcess glycogen biosynthetic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. MetaCyc:GLYCOGENSYNTH-PWY go-plus.json glycogen synthesis|glycogen formation|glycogen biosynthesis|glycogen anabolism http://purl.obolibrary.org/obo/GO_0005978 GO:0030934 biolink:CellularComponent anchoring collagen complex Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures. go-plus.json connecting collagen|linking collagen http://purl.obolibrary.org/obo/GO_0030934 CHEBI:17271 biolink:ChemicalSubstance 3-phosphonatopyruvate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17271 GO:0005979 biolink:BiologicalProcess regulation of glycogen biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. go-plus.json regulation of glycogen anabolism|regulation of glycogen synthesis|regulation of glycogen formation|regulation of glycogen biosynthesis http://purl.obolibrary.org/obo/GO_0005979 CHEBI:17272 biolink:ChemicalSubstance propionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17272 chebi_ph7_3 GO:0030935 biolink:CellularComponent sheet-forming collagen trimer A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers assemble into a sheet. go-plus.json hexagonal network-forming collagen http://purl.obolibrary.org/obo/GO_0030935 GO:0005976 biolink:BiologicalProcess polysaccharide metabolic process The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json glycan metabolic process|polysaccharide metabolism|multicellular organismal polysaccharide metabolic process|glycan metabolism http://purl.obolibrary.org/obo/GO_0005976 goslim_pir GO:0030932 biolink:CellularComponent amyloplast ADPG pyrophosphorylase complex An ADPG pyrophosphorylase complex found in the amyloplast. go-plus.json http://purl.obolibrary.org/obo/GO_0030932 GO:0030933 biolink:CellularComponent chloroplast ADPG pyrophosphorylase complex An ADPG pyrophosphorylase complex found in the chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0030933 GO:0005977 biolink:BiologicalProcess glycogen metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. go-plus.json glycogen metabolism http://purl.obolibrary.org/obo/GO_0005977 CHEBI:17270 biolink:ChemicalSubstance glycerol 2-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17270 GO:0005974 biolink:CellularComponent obsolete fibrinogen gamma chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json fibrinogen gamma chain http://purl.obolibrary.org/obo/GO_0005974 GO:0030930 biolink:CellularComponent homotetrameric ADPG pyrophosphorylase complex A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species. go-plus.json http://purl.obolibrary.org/obo/GO_0030930 GO:0005975 biolink:BiologicalProcess carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. Wikipedia:Carbohydrate_metabolism go-plus.json multicellular organismal carbohydrate metabolic process|single-organism carbohydrate metabolic process|carbohydrate metabolism http://purl.obolibrary.org/obo/GO_0005975 goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast|goslim_agr|goslim_candida|goslim_pir|goslim_plant GO:0030931 biolink:CellularComponent heterotetrameric ADPG pyrophosphorylase complex A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0030931 GO:0005972 biolink:CellularComponent obsolete fibrinogen alpha chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json fibrinogen alpha chain http://purl.obolibrary.org/obo/GO_0005972 GO:0005973 biolink:CellularComponent obsolete fibrinogen beta chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json fibrinogen beta chain http://purl.obolibrary.org/obo/GO_0005973 GO:0005970 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005970 GO:0005971 biolink:CellularComponent ribonucleoside-diphosphate reductase complex An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor. go-plus.json RNR complex|ribonucleotide reductase complex http://purl.obolibrary.org/obo/GO_0005971 GO:0030938 biolink:CellularComponent collagen type XVIII trimer A collagen homotrimer of alpha1(XVIII) chains. go-plus.json http://purl.obolibrary.org/obo/GO_0030938 GO:0030939 biolink:BiologicalProcess obsolete response to long-day photoperiod OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the light phase being longer than the dark. go-plus.json response to long-day photoperiod http://purl.obolibrary.org/obo/GO_0030939 GO:0030936 biolink:CellularComponent transmembrane collagen trimer Any collagen trimer that passes through a lipid bilayer membrane. go-plus.json MACIT http://purl.obolibrary.org/obo/GO_0030936 GO:0030937 biolink:CellularComponent collagen type XVII trimer A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin. go-plus.json http://purl.obolibrary.org/obo/GO_0030937 CHEBI:17268 biolink:ChemicalSubstance myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17268 chebi_ph7_3 NCBITaxon:5476 biolink:OrganismalEntity Candida albicans go-plus.json Parasaccharomyces albicans|Saccharomyces albicans|Dematium albicans|Procandida albicans|Monilia albicans|Syringospora albicans|Candida albicans var. stellatoidea|Procandida stellatoidea|Mycotorula albicans|Monilia stellatoidea|Endomyces albicans|Myceloblastanon albicans|Oidium albicans|Candida stellatoidea http://purl.obolibrary.org/obo/NCBITaxon_5476 CHEBI:17269 biolink:ChemicalSubstance Latia luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17269 chebi_ph7_3 CHEBI:17266 biolink:ChemicalSubstance L-sorbose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17266 CHEBI:17264 biolink:ChemicalSubstance phosphatidylglycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17264 CHEBI:17265 biolink:ChemicalSubstance O-(1->4)-alpha-L-dihydrostreptosylstreptidine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17265 CHEBI:17262 biolink:ChemicalSubstance dTDP-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17262 CHEBI:17263 biolink:ChemicalSubstance estrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17263 chebi_ph7_3 GO:0005989 biolink:BiologicalProcess lactose biosynthetic process The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose. go-plus.json lactose anabolism|lactose biosynthesis|lactose synthesis|lactose formation http://purl.obolibrary.org/obo/GO_0005989 GO:0030923 biolink:BiologicalProcess metal incorporation into metallo-oxygen cluster The formation of a cluster of several metal atoms, including manganese or calcium, with one or more bridging (mu-bond) oxygen atoms; amino acids residues in proteins that may ligate the metal oxygen cluster are histidine, aspartate, and glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0030923 CHEBI:17260 biolink:ChemicalSubstance butanoyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17260 GO:0030924 biolink:BiologicalProcess manganese incorporation into metallo-oxygen cluster The incorporation of manganese into a metallo-oxygen cluster. go-plus.json http://purl.obolibrary.org/obo/GO_0030924 CHEBI:17261 biolink:ChemicalSubstance N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17261 GO:0030921 biolink:BiologicalProcess peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues. RESID:AA0183 go-plus.json http://purl.obolibrary.org/obo/GO_0030921 GO:0005987 biolink:BiologicalProcess sucrose catabolic process The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside. go-plus.json sucrose breakdown|sucrose catabolism|sucrose degradation http://purl.obolibrary.org/obo/GO_0005987 GO:0030922 biolink:BiologicalProcess peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues. RESID:AA0365 go-plus.json http://purl.obolibrary.org/obo/GO_0030922 GO:0005988 biolink:BiologicalProcess lactose metabolic process The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose. go-plus.json lactose metabolism http://purl.obolibrary.org/obo/GO_0005988 GO:0005985 biolink:BiologicalProcess sucrose metabolic process The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside. go-plus.json sucrose metabolism http://purl.obolibrary.org/obo/GO_0005985 GO:0005986 biolink:BiologicalProcess sucrose biosynthetic process The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside. MetaCyc:SUCSYN-PWY go-plus.json sucrose anabolism|sucrose synthesis|sucrose formation|sucrose biosynthesis http://purl.obolibrary.org/obo/GO_0005986 GO:0030920 biolink:BiologicalProcess peptidyl-serine acetylation The acetylation of peptidyl-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0030920 GO:0005983 biolink:BiologicalProcess starch catabolic process The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants. MetaCyc:PWY-842 go-plus.json starch degradation|starch catabolism|starch breakdown http://purl.obolibrary.org/obo/GO_0005983 GO:0005984 biolink:BiologicalProcess disaccharide metabolic process The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units. go-plus.json disaccharide metabolism http://purl.obolibrary.org/obo/GO_0005984 GO:0005981 biolink:BiologicalProcess regulation of glycogen catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. go-plus.json regulation of glycogen catabolism|regulation of glycogen degradation|regulation of glycogen breakdown|regulation of glycogenolysis http://purl.obolibrary.org/obo/GO_0005981 CHEBI:330772 biolink:ChemicalSubstance dichloroarcyriaflavin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_330772 chebi_ph7_3 GO:0005982 biolink:BiologicalProcess starch metabolic process The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose. go-plus.json starch metabolism http://purl.obolibrary.org/obo/GO_0005982 GO:0030929 biolink:CellularComponent ADPG pyrophosphorylase complex Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0030929 goslim_pir GO:0005980 biolink:BiologicalProcess glycogen catabolic process The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. MetaCyc:GLYCOCAT-PWY go-plus.json glycogen breakdown|glycogenolysis|glycogen catabolism|glycogen degradation http://purl.obolibrary.org/obo/GO_0005980 CHEBI:42223 biolink:ChemicalSubstance emodin go-plus.json http://purl.obolibrary.org/obo/CHEBI_42223 GO:0030927 biolink:BiologicalProcess manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site. RESID:AA0366 go-plus.json http://purl.obolibrary.org/obo/GO_0030927 GO:0015308 biolink:MolecularActivity amiloride:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out). go-plus.json amiloride:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015308 GO:0030928 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030928 GO:0015309 biolink:MolecularActivity cycloheximide:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out). go-plus.json cycloheximide:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015309 GO:0030925 biolink:BiologicalProcess calcium incorporation into metallo-oxygen cluster The incorporation of calcium into a metallo-oxygen cluster. go-plus.json http://purl.obolibrary.org/obo/GO_0030925 GO:0030926 biolink:BiologicalProcess calcium incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide The incorporation of calcium into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site. RESID:AA0366 go-plus.json http://purl.obolibrary.org/obo/GO_0030926 GO:0015304 biolink:MolecularActivity glucose uniporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in). go-plus.json galactose, glucose uniporter activity http://purl.obolibrary.org/obo/GO_0015304 GO:0015305 biolink:MolecularActivity obsolete lactose, galactose:proton symporter activity OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in). go-plus.json lactose, galactose:hydrogen symporter activity|lactose, galactose:proton symporter activity|lactose,galactose:proton symporter activity http://purl.obolibrary.org/obo/GO_0015305 GO:0015306 biolink:MolecularActivity sialate:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in). go-plus.json cation/sialate symporter activity|sialate transporter activity|cation:sialate symporter activity|sialate/cation symporter activity http://purl.obolibrary.org/obo/GO_0015306 GO:0015307 biolink:MolecularActivity obsolete drug:proton antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out). go-plus.json carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|drug:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015307 GO:0015300 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015300 GO:0015301 biolink:MolecularActivity anion:anion antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out). Reactome:R-HSA-561041 go-plus.json anion exchanger activity|bicarbonate:chloride antiporter http://purl.obolibrary.org/obo/GO_0015301 GO:0015302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015302 CHEBI:17259 biolink:ChemicalSubstance CDP-3,6-dideoxy-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17259 GO:0015303 biolink:MolecularActivity obsolete galactose, glucose uniporter activity OBSOLETE. Catalysis of the reaction: galactose or glucose(out) = galactose or glucose(in). go-plus.json galactose, glucose uniporter activity http://purl.obolibrary.org/obo/GO_0015303 CHEBI:17257 biolink:ChemicalSubstance bis-gamma-glutamylcystine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17257 CHEBI:17258 biolink:ChemicalSubstance 7H-purine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17258 chebi_ph7_3 CHEBI:17255 biolink:ChemicalSubstance N-carbamoyl-D-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17255 CHEBI:17256 biolink:ChemicalSubstance 2'-deoxyadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17256 chebi_ph7_3 CHEBI:17253 biolink:ChemicalSubstance 1,2-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17253 chebi_ph7_3 CHEBI:17254 biolink:ChemicalSubstance 4-methylcatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17254 chebi_ph7_3 CHEBI:17251 biolink:ChemicalSubstance pentalenene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17251 chebi_ph7_3 CHEBI:17252 biolink:ChemicalSubstance 17alpha-hydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17252 chebi_ph7_3 GO:0005956 biolink:CellularComponent protein kinase CK2 complex A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein. go-plus.json casein kinase II complex http://purl.obolibrary.org/obo/GO_0005956 GO:0030912 biolink:BiologicalProcess response to deep water Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0030912 CHEBI:17293 biolink:ChemicalSubstance 2-aminophenoxazin-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17293 chebi_ph7_3 GO:0005957 biolink:CellularComponent obsolete debranching enzyme OBSOLETE. (Was not defined before being made obsolete). go-plus.json debranching enzyme http://purl.obolibrary.org/obo/GO_0005957 GO:0030913 biolink:BiologicalProcess paranodal junction assembly Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier. go-plus.json paranodal axoglial junction formation|paranodal junction biosynthesis|paranodal junction formation http://purl.obolibrary.org/obo/GO_0030913 CHEBI:17294 biolink:ChemicalSubstance 4,21-dehydrogeissoschizine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17294 chebi_ph7_3 GO:0005954 biolink:CellularComponent calcium- and calmodulin-dependent protein kinase complex An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins. go-plus.json CaMKII|CAMK2|calcium/calmodulin-dependent protein kinase complex http://purl.obolibrary.org/obo/GO_0005954 GO:0030910 biolink:BiologicalProcess olfactory placode formation The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0030910 CHEBI:17291 biolink:ChemicalSubstance L-fuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17291 GO:0030911 biolink:MolecularActivity TPR domain binding Binding to a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices. go-plus.json tetratricopeptide repeat domain binding http://purl.obolibrary.org/obo/GO_0030911 GO:0005955 biolink:CellularComponent calcineurin complex A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin. go-plus.json protein phosphatase type 2B complex|calcium-dependent protein serine/threonine phosphatase complex http://purl.obolibrary.org/obo/GO_0005955 CHEBI:17292 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_17292 chebi_ph7_3 GO:0005952 biolink:CellularComponent cAMP-dependent protein kinase complex An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer. go-plus.json 3',5' cAMP-dependent protein kinase complex|PKA|cyclic AMP-dependent protein kinase complex|adenosine 3',5'-cyclophosphate-dependent protein kinase complex|3',5'-cAMP-dependent protein kinase complex http://purl.obolibrary.org/obo/GO_0005952 GO:0005953 biolink:CellularComponent CAAX-protein geranylgeranyltransferase complex A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0005953 CHEBI:17290 biolink:ChemicalSubstance (S)-3-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17290 GO:0005950 biolink:CellularComponent anthranilate synthase complex A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine. go-plus.json http://purl.obolibrary.org/obo/GO_0005950 GO:0005951 biolink:CellularComponent carbamoyl-phosphate synthase complex A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events. go-plus.json carbamoyl phosphate synthase complex|arginine-specific carbamoyl phosphate synthetase complex|carbamoyl-phosphate synthase arginine-specific complex http://purl.obolibrary.org/obo/GO_0005951 CHEBI:32888 biolink:ChemicalSubstance gamma-hexachlorocyclohexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_32888 chebi_ph7_3 GO:0030918 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030918 GO:0030919 biolink:BiologicalProcess peptidyl-serine O-acetylation The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine. RESID:AA0364 go-plus.json http://purl.obolibrary.org/obo/GO_0030919 GO:0030916 biolink:BiologicalProcess otic vesicle formation The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. go-plus.json otocyst formation|otocyst biosynthesis http://purl.obolibrary.org/obo/GO_0030916 GO:0030917 biolink:BiologicalProcess midbrain-hindbrain boundary development The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. go-plus.json isthmic organizer development|isthmus development|MHB development|isthmomesencephalic boundary development|midbrain-hindbrain orgainizer development http://purl.obolibrary.org/obo/GO_0030917 GO:0030914 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030914 GO:0030915 biolink:CellularComponent Smc5-Smc6 complex A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans. go-plus.json http://purl.obolibrary.org/obo/GO_0030915 CHEBI:42215 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_42215 CHEBI:17289 biolink:ChemicalSubstance homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17289 CHEBI:17286 biolink:ChemicalSubstance deacetylisoipecoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_17286 CHEBI:17287 biolink:ChemicalSubstance N-phosphocreatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17287 GO:0005958 biolink:CellularComponent DNA-dependent protein kinase-DNA ligase 4 complex A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV. go-plus.json http://purl.obolibrary.org/obo/GO_0005958 CHEBI:17284 biolink:ChemicalSubstance 5-phospho-D-ribosylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17284 GO:0005959 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005959 CHEBI:17285 biolink:ChemicalSubstance L-cysteic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17285 GO:0030901 biolink:BiologicalProcess midbrain development The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). go-plus.json mesencephalon development http://purl.obolibrary.org/obo/GO_0030901 GO:0005967 biolink:CellularComponent mitochondrial pyruvate dehydrogenase complex Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase. go-plus.json pyruvate dehydrogenase complex (lipoamide) http://purl.obolibrary.org/obo/GO_0005967 CHEBI:17282 biolink:ChemicalSubstance 3-(indol-3-yl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17282 chebi_ph7_3 CHEBI:17283 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17283 GO:0030902 biolink:BiologicalProcess hindbrain development The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). go-plus.json rhombencephalon development http://purl.obolibrary.org/obo/GO_0030902 GO:0005968 biolink:CellularComponent Rab-protein geranylgeranyltransferase complex An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein). go-plus.json Rab geranylgeranyltransferase complex|RabGGTase complex|RAB-protein geranylgeranyltransferase complex|GGTase-II complex http://purl.obolibrary.org/obo/GO_0005968 GO:0005965 biolink:CellularComponent protein farnesyltransferase complex A protein complex that possesses protein farnesyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0005965 GO:0005966 biolink:CellularComponent cyclic-nucleotide phosphodiesterase complex An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide. go-plus.json photoreceptor cyclic-nucleotide phosphodiesterase complex http://purl.obolibrary.org/obo/GO_0005966 CHEBI:17281 biolink:ChemicalSubstance 2-deoxy-D-ribono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17281 chebi_ph7_3 GO:0030900 biolink:BiologicalProcess forebrain development The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). go-plus.json prosencephalon development http://purl.obolibrary.org/obo/GO_0030900 GO:0005963 biolink:CellularComponent magnesium-dependent protein serine/threonine phosphatase complex An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0005963 GO:0005964 biolink:CellularComponent phosphorylase kinase complex An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a. go-plus.json http://purl.obolibrary.org/obo/GO_0005964 GO:0005961 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005961 GO:0005962 biolink:CellularComponent mitochondrial isocitrate dehydrogenase complex (NAD+) Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity. go-plus.json http://purl.obolibrary.org/obo/GO_0005962 GO:0030909 biolink:BiologicalProcess non-intein-mediated protein splicing The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030909 CHEBI:32898 biolink:ChemicalSubstance baccatin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_32898 chebi_ph7_3 CHEBI:42202 biolink:ChemicalSubstance daidzein 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_42202 chebi_ph7_3 GO:0005960 biolink:CellularComponent glycine cleavage complex A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T. Wikipedia:Glycine_decarboxylase_complex go-plus.json glycine cleavage system|glycine decarboxylase complex|glycine dehydrogenase (decarboxylating) complex|glycine dehydrogenase complex (decarboxylating)|glycine synthase complex http://purl.obolibrary.org/obo/GO_0005960 goslim_pir GO:0030907 biolink:CellularComponent MBF transcription complex A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p. go-plus.json MBF|Mlu1-box binding factor|DSC1 transcription factor complex http://purl.obolibrary.org/obo/GO_0030907 GO:0030908 biolink:BiologicalProcess protein splicing The post-translational removal of peptide sequences from within a protein sequence. Wikipedia:Protein_splicing go-plus.json http://purl.obolibrary.org/obo/GO_0030908 GO:0030905 biolink:CellularComponent retromer, tubulation complex The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6. go-plus.json SNX-BAR dimer|heterodimeric membrane-deforming retromer subcomplex|retromer complex, outer shell http://purl.obolibrary.org/obo/GO_0030905 GO:0030906 biolink:CellularComponent retromer, cargo-selective complex The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals. go-plus.json retromer complex, inner shell|retromer, cargo recognition complex|cargo-selective retromer subcomplex|retromer CSC|retromer, CRC http://purl.obolibrary.org/obo/GO_0030906 GO:0030903 biolink:BiologicalProcess notochord development The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. go-plus.json http://purl.obolibrary.org/obo/GO_0030903 GO:0030904 biolink:CellularComponent retromer complex A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35. go-plus.json http://purl.obolibrary.org/obo/GO_0030904 goslim_pir CHEBI:32892 biolink:ChemicalSubstance nonane go-plus.json http://purl.obolibrary.org/obo/CHEBI_32892 chebi_ph7_3 CHEBI:32896 biolink:ChemicalSubstance (2R)-O-phospho-3-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32896 CHEBI:32897 biolink:ChemicalSubstance 10-deacetyl-2-debenzoylbaccatin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_32897 chebi_ph7_3 CHEBI:17279 biolink:ChemicalSubstance N-succinyl-LL-2,6-diaminopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17279 CHEBI:17277 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17277 CHEBI:17278 biolink:ChemicalSubstance 5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17278 chebi_ph7_3 CHEBI:17275 biolink:ChemicalSubstance 2-isopropylmaleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17275 CHEBI:17276 biolink:ChemicalSubstance phloretin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17276 chebi_ph7_3 GO:0005969 biolink:CellularComponent serine-pyruvate aminotransferase complex An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate. go-plus.json serine-pyruvate aminotransferase, type 1 complex|serine-pyruvate aminotransferase, type 2B complex http://purl.obolibrary.org/obo/GO_0005969 CHEBI:17274 biolink:ChemicalSubstance aldehydo-N-acyl-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17274 chebi_ph7_3 GO:0005934 biolink:CellularComponent cellular bud tip The end of a cellular bud distal to the site of attachment to the mother cell. go-plus.json http://purl.obolibrary.org/obo/GO_0005934 GO:0005935 biolink:CellularComponent cellular bud neck The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding. go-plus.json http://purl.obolibrary.org/obo/GO_0005935 GO:0005932 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005932 GO:0005933 biolink:CellularComponent cellular bud A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated. go-plus.json http://purl.obolibrary.org/obo/GO_0005933 goslim_pir|goslim_candida|goslim_yeast GO:0005930 biolink:CellularComponent axoneme The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. Wikipedia:Axoneme go-plus.json cilium axoneme|flagellum axoneme|flagellar axoneme|ciliary axoneme http://purl.obolibrary.org/obo/GO_0005930 goslim_pir GO:0005931 biolink:CellularComponent axonemal nexin link A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules. go-plus.json nexin complex|axonemal interdoublet link http://purl.obolibrary.org/obo/GO_0005931 CHEBI:32867 biolink:ChemicalSubstance D-prolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32867 CHEBI:81874 biolink:ChemicalSubstance nogalaviketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_81874 CHEBI:32868 biolink:ChemicalSubstance D-prolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32868 CHEBI:81873 biolink:ChemicalSubstance 12-deoxynogalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_81873 CHEBI:32860 biolink:ChemicalSubstance valinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32860 CHEBI:17228 biolink:ChemicalSubstance taurocyamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17228 CHEBI:17229 biolink:ChemicalSubstance 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17229 chebi_ph7_3 CHEBI:32862 biolink:ChemicalSubstance L-prolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32862 CHEBI:17226 biolink:ChemicalSubstance rosmarinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17226 CHEBI:32863 biolink:ChemicalSubstance secondary amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32863 CHEBI:32864 biolink:ChemicalSubstance L-prolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32864 CHEBI:91209 biolink:ChemicalSubstance glycosmisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_91209 CHEBI:17224 biolink:ChemicalSubstance 4-methylumbelliferone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17224 chebi_ph7_3 CHEBI:17225 biolink:ChemicalSubstance salutaridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17225 CHEBI:17223 biolink:ChemicalSubstance polyprenyl glucosyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17223 GO:0005938 biolink:CellularComponent cell cortex The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. Wikipedia:Cell_cortex go-plus.json cell periphery|peripheral cytoplasm http://purl.obolibrary.org/obo/GO_0005938 goslim_yeast|goslim_candida|goslim_aspergillus CHEBI:17221 biolink:ChemicalSubstance beta-myrcene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17221 chebi_ph7_3 GO:0005936 biolink:CellularComponent obsolete shmoo OBSOLETE. The characteristic projection formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles. go-plus.json shmoo http://purl.obolibrary.org/obo/GO_0005936 GO:0005937 biolink:CellularComponent mating projection The projection formed by unicellular fungi in response to mating pheromone. go-plus.json conjugation tube|shmoo http://purl.obolibrary.org/obo/GO_0005937 goslim_pir GO:0005945 biolink:CellularComponent 6-phosphofructokinase complex A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known. go-plus.json http://purl.obolibrary.org/obo/GO_0005945 GO:0005946 biolink:CellularComponent alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present. go-plus.json trehalose-6-phosphate synthase complex|UDP-glucose-glucosephosphate glucosyltransferase complex|trehalose-6-phosphate synthase/phosphatase http://purl.obolibrary.org/obo/GO_0005946 GO:0005943 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class IA A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways. go-plus.json 1-phosphatidylinositol-4-phosphate kinase, class IA complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex|phosphoinositide 3-kinase complex, class IA|class IA PI3K complex http://purl.obolibrary.org/obo/GO_0005943 GO:0005944 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class IB A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks. go-plus.json 1-phosphatidylinositol-4-phosphate kinase, class IB complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex|phosphoinositide 3-kinase complex, class IB|class IB PI3K complex http://purl.obolibrary.org/obo/GO_0005944 GO:0005941 biolink:CellularComponent obsolete unlocalized protein complex OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products. go-plus.json unlocalized protein complex http://purl.obolibrary.org/obo/GO_0005941 GO:0005942 biolink:CellularComponent phosphatidylinositol 3-kinase complex A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too. go-plus.json PIK3CA-PIK3R1 complex|phosphoinositide 3-kinase complex|1-phosphatidylinositol 3-kinase complex|PI3-kinase p85-subunit alpha- PI3-kinase p110 complex|PIK3C3-PIK3R4 complex|PI3K complex http://purl.obolibrary.org/obo/GO_0005942 goslim_pir GO:0005940 biolink:CellularComponent septin ring A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form. Wikipedia:Septin_ring go-plus.json http://purl.obolibrary.org/obo/GO_0005940 CHEBI:32876 biolink:ChemicalSubstance tertiary amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32876 chebi_ph7_3 CHEBI:32877 biolink:ChemicalSubstance primary amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_32877 CHEBI:32878 biolink:ChemicalSubstance alkene go-plus.json http://purl.obolibrary.org/obo/CHEBI_32878 CHEBI:32879 biolink:ChemicalSubstance propane go-plus.json http://purl.obolibrary.org/obo/CHEBI_32879 chebi_ph7_3 CHEBI:17219 biolink:ChemicalSubstance limonene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17219 chebi_ph7_3 CHEBI:32871 biolink:ChemicalSubstance prolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32871 CHEBI:32872 biolink:ChemicalSubstance prolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32872 CHEBI:17217 biolink:ChemicalSubstance 2-butenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17217 CHEBI:17215 biolink:ChemicalSubstance methyl L-tyrosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17215 chebi_ph7_3 CHEBI:32874 biolink:ChemicalSubstance proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32874 chebi_ph7_3 CHEBI:32875 biolink:ChemicalSubstance methyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32875 chebi_ph7_3 CHEBI:17216 biolink:ChemicalSubstance oxidized Cypridina luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17216 CHEBI:17213 biolink:ChemicalSubstance D-lysopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17213 CHEBI:17214 biolink:ChemicalSubstance (2S)-2-isopropyl-3-oxosuccinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17214 chebi_ph7_3 CHEBI:17211 biolink:ChemicalSubstance geranyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17211 CHEBI:17212 biolink:ChemicalSubstance 1,2-dihydroxydibenzothiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17212 chebi_ph7_3 GO:0005949 biolink:CellularComponent obsolete aminoadipate-semialdehyde dehydrogenase complex OBSOLETE. A heterodimeric enzyme composed of an alpha and beta subunit. Catalyzes the formation of L-2-aminoadipate from L-2-aminoadipate 6-semialdehyde. go-plus.json aminoadipate-semialdehyde dehydrogenase complex http://purl.obolibrary.org/obo/GO_0005949 CHEBI:17210 biolink:ChemicalSubstance (S)-4-hydroxymandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17210 chebi_ph7_3 GO:0005947 biolink:CellularComponent mitochondrial alpha-ketoglutarate dehydrogenase complex Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity. go-plus.json 2-oxoglutarate dehydrogenase complex http://purl.obolibrary.org/obo/GO_0005947 GO:0005948 biolink:CellularComponent acetolactate synthase complex A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate. go-plus.json acetohydroxyacid synthase complex http://purl.obolibrary.org/obo/GO_0005948 GO:0005912 biolink:CellularComponent adherens junction A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. Wikipedia:Adherens_junction go-plus.json cell-cell adherens junction http://purl.obolibrary.org/obo/GO_0005912 GO:0005913 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005913 CHEBI:17250 biolink:ChemicalSubstance 2-hydroxy-4-oxobutane-1,2,4-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17250 GO:0005911 biolink:CellularComponent cell-cell junction A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. NIF_Subcellular:sao1922892319 go-plus.json intercellular junction http://purl.obolibrary.org/obo/GO_0005911 NCBITaxon:746128 biolink:OrganismalEntity Aspergillus fumigatus go-plus.json Sartorya fumigata|Aspergillus fumigates|Neosartorya fumigata http://purl.obolibrary.org/obo/NCBITaxon_746128 CHEBI:32844 biolink:ChemicalSubstance N-acetyl-4-O-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_32844 CHEBI:32845 biolink:ChemicalSubstance serinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32845 CHEBI:32846 biolink:ChemicalSubstance serinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32846 CHEBI:32848 biolink:ChemicalSubstance serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_32848 chebi_ph7_3 CHEBI:91228 biolink:ChemicalSubstance 2,2-dihydroxyspirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_91228 chebi_ph7_3 CHEBI:295975 biolink:ChemicalSubstance choline phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_295975 chebi_ph7_3 CHEBI:32840 biolink:ChemicalSubstance D-serinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32840 CHEBI:91229 biolink:ChemicalSubstance 2'-hydroxy-2-oxospirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_91229 chebi_ph7_3 CHEBI:32841 biolink:ChemicalSubstance D-serinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32841 CHEBI:17248 biolink:ChemicalSubstance 6-lactoyl-5,6,7,8-tetrahydropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17248 chebi_ph7_3 CHEBI:17249 biolink:ChemicalSubstance D-nopaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17249 CHEBI:17246 biolink:ChemicalSubstance poly(vinyl alcohol) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_17246 chebi_ph7_3 CHEBI:17247 biolink:ChemicalSubstance N-isopropylammelide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17247 chebi_ph7_3 GO:0005918 biolink:CellularComponent septate junction A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods. NIF_Subcellular:sao427941916 go-plus.json septate desmosome http://purl.obolibrary.org/obo/GO_0005918 CHEBI:17244 biolink:ChemicalSubstance 5,6-dihydroquinoline-2,5,6-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17244 chebi_ph7_3 CHEBI:17245 biolink:ChemicalSubstance carbon monoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17245 chebi_ph7_3 GO:0005919 biolink:CellularComponent pleated septate junction A septate junction in which regular arrays of electron-dense septae span the intermembrane space. go-plus.json pleated desmosome http://purl.obolibrary.org/obo/GO_0005919 CHEBI:91227 biolink:ChemicalSubstance 2-hydroxyspirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_91227 chebi_ph7_3 GO:0005916 biolink:CellularComponent fascia adherens A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes. Wikipedia:Fascia_adherens go-plus.json http://purl.obolibrary.org/obo/GO_0005916 CHEBI:17242 biolink:ChemicalSubstance dehydroascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17242 GO:0005917 biolink:CellularComponent nephrocyte diaphragm A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates. go-plus.json nephrocyte junction http://purl.obolibrary.org/obo/GO_0005917 CHEBI:17243 biolink:ChemicalSubstance mono(2-ethylhexyl) phthalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17243 CHEBI:91221 biolink:ChemicalSubstance 2-hydroxyspheroidene go-plus.json http://purl.obolibrary.org/obo/CHEBI_91221 chebi_ph7_3 GO:0005914 biolink:CellularComponent spot adherens junction A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens. go-plus.json punctum adherens|dense plaque http://purl.obolibrary.org/obo/GO_0005914 CHEBI:17240 biolink:ChemicalSubstance itaconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17240 chebi_ph7_3 CHEBI:91223 biolink:ChemicalSubstance 2,2-dihydroxyspheroidene go-plus.json http://purl.obolibrary.org/obo/CHEBI_91223 chebi_ph7_3 GO:0005915 biolink:CellularComponent zonula adherens A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells. NIF_Subcellular:sao1400623473 go-plus.json intermediate junction|adhesion belt|belt desmosome|zonula adhaerens http://purl.obolibrary.org/obo/GO_0005915 CHEBI:17241 biolink:ChemicalSubstance 1H-pyrazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_17241 chebi_ph7_3 GO:0005923 biolink:CellularComponent bicellular tight junction An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. Wikipedia:Tight_junction|NIF_Subcellular:sao1939999134 go-plus.json zonula occludens http://purl.obolibrary.org/obo/GO_0005923 GO:0005924 biolink:CellularComponent obsolete cell-substrate adherens junction OBSOLETE. An adherens junction which connects a cell to the extracellular matrix. go-plus.json hemi-adherens junction http://purl.obolibrary.org/obo/GO_0005924 GO:0005921 biolink:CellularComponent gap junction A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins. NIF_Subcellular:sao118541872|Wikipedia:Gap_junction go-plus.json zonula communicans|intercellular gap junction channel|gap junction plaque|communicating junction|gap junction macula|macula communicans|electrotonic synapse|electrical synapse http://purl.obolibrary.org/obo/GO_0005921 GO:0005922 biolink:CellularComponent connexin complex An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction. NIF_Subcellular:sao445019788 go-plus.json connexon complex|connexon http://purl.obolibrary.org/obo/GO_0005922 GO:0005920 biolink:CellularComponent smooth septate junction A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions. go-plus.json zonula continua http://purl.obolibrary.org/obo/GO_0005920 CHEBI:32855 biolink:ChemicalSubstance D-valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32855 CHEBI:32856 biolink:ChemicalSubstance D-valinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32856 CHEBI:32857 biolink:ChemicalSubstance D-valyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32857 CHEBI:32859 biolink:ChemicalSubstance valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32859 CHEBI:17239 biolink:ChemicalSubstance CDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17239 CHEBI:32851 biolink:ChemicalSubstance L-valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_32851 CHEBI:17237 biolink:ChemicalSubstance (E)-4-(trimethylammonio)but-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17237 chebi_ph7_3 CHEBI:32852 biolink:ChemicalSubstance L-valinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_32852 CHEBI:32853 biolink:ChemicalSubstance L-valyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_32853 CHEBI:17236 biolink:ChemicalSubstance 2-hydroxy-6-oxohexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17236 GO:0005929 biolink:CellularComponent cilium A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. Wikipedia:Cilium|NIF_Subcellular:sao787716553|FMA:67181 go-plus.json primary cilium|eukaryotic flagellum|flagellum|microtubule-based flagellum http://purl.obolibrary.org/obo/GO_0005929 goslim_generic|goslim_chembl|goslim_pir|goslim_drosophila CHEBI:17233 biolink:ChemicalSubstance (3Z,5S)-3-(1-hydroxyethylidene)-5-{[4-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}pyrrolidine-2,4-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17233 CHEBI:17234 biolink:ChemicalSubstance glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17234 CHEBI:17231 biolink:ChemicalSubstance m-cresol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17231 chebi_ph7_3 GO:0005927 biolink:CellularComponent muscle tendon junction A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons. go-plus.json myotendinous junction http://purl.obolibrary.org/obo/GO_0005927 GO:0005928 biolink:CellularComponent obsolete apical hemi-adherens junction OBSOLETE. A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle. go-plus.json apical cell-substrate adherens junction|apical dense plaque http://purl.obolibrary.org/obo/GO_0005928 CHEBI:17232 biolink:ChemicalSubstance L-glutamic 5-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17232 GO:0005925 biolink:CellularComponent focal adhesion A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). Wikipedia:Focal_adhesion go-plus.json HAJ|connecting hemi-adherens junction|hemi-adherens junction|focal contact|adhesion plaque http://purl.obolibrary.org/obo/GO_0005925 CHEBI:17230 biolink:ChemicalSubstance homocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17230 GO:0005926 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005926 CHEBI:134027 biolink:ChemicalSubstance 1,2-bis(octadec-9-enoyl)phosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134027 GO:0015377 biolink:MolecularActivity cation:chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in). go-plus.json cation:chloride cotransporter activity http://purl.obolibrary.org/obo/GO_0015377 GO:0015378 biolink:MolecularActivity sodium:chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in). Reactome:R-HSA-426130|Reactome:R-HSA-5623705 go-plus.json http://purl.obolibrary.org/obo/GO_0015378 GO:0015379 biolink:MolecularActivity potassium:chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in). Reactome:R-HSA-5623806|Reactome:R-HSA-426155 go-plus.json potassium ion symporter activity http://purl.obolibrary.org/obo/GO_0015379 GO:0015373 biolink:MolecularActivity anion:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in). go-plus.json monovalent anion:sodium symporter activity http://purl.obolibrary.org/obo/GO_0015373 GO:0015374 biolink:MolecularActivity neutral, basic amino acid:sodium:chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in). go-plus.json neutral, cationic amino acid:sodium:chloride symporter activity http://purl.obolibrary.org/obo/GO_0015374 GO:0015375 biolink:MolecularActivity glycine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). Reactome:R-HSA-444120|Reactome:R-HSA-5660840 go-plus.json http://purl.obolibrary.org/obo/GO_0015375 GO:0015376 biolink:MolecularActivity obsolete betaine/GABA:sodium symporter activity OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in). go-plus.json betaine/GABA:sodium symporter activity http://purl.obolibrary.org/obo/GO_0015376 CHEBI:134022 biolink:ChemicalSubstance N-arachidonoyl-L-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134022 chebi_ph7_3 GO:0015370 biolink:MolecularActivity solute:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in). Reactome:R-HSA-8876283 go-plus.json proline/glycine/betaine:hydrogen/sodium symporter activity http://purl.obolibrary.org/obo/GO_0015370 GO:0015371 biolink:MolecularActivity galactose:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015371 CHEBI:134020 biolink:ChemicalSubstance N-oleoyl-L-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134020 chebi_ph7_3 GO:0015372 biolink:MolecularActivity obsolete glutamate/aspartate:sodium symporter activity OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in). go-plus.json glutamate/aspartate:sodium symporter activity http://purl.obolibrary.org/obo/GO_0015372 CHEBI:134021 biolink:ChemicalSubstance N-oleoyl-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134021 GO:0015390 biolink:MolecularActivity purine-specific nucleoside:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015390 OBA:VT0010248 biolink:OntologyClass hemolymphoid system trait The quality when measured in hemolymphoid system. go-plus.json http://purl.obolibrary.org/obo/OBA_VT0010248 CHEBI:134035 biolink:ChemicalSubstance N-oleoyl-L-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134035 chebi_ph7_3 GO:0015388 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015388 GO:0015389 biolink:MolecularActivity pyrimidine- and adenine-specific:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015389 GO:0015384 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015384 GO:0015385 biolink:MolecularActivity sodium:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). Reactome:R-HSA-5661039|Reactome:R-HSA-5661086|Reactome:R-HSA-426015|Reactome:R-HSA-425965|Reactome:R-HSA-2872463|Reactome:R-HSA-425994|RHEA:29251|Reactome:R-HSA-425983|Reactome:R-HSA-2872444 go-plus.json pH-dependent sodium:proton antiporter activity|sodium/hydrogen antiporter activity|sodium:hydrogen exchanger|pH-dependent sodium:hydrogen antiporter activity|sodium:hydrogen exchange activity|sodium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015385 GO:0015386 biolink:MolecularActivity potassium:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in). RHEA:29467 go-plus.json potassium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015386 GO:0015387 biolink:MolecularActivity potassium:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in). RHEA:28490 go-plus.json potassium:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015387 CHEBI:134033 biolink:ChemicalSubstance N-oleoyl-L-glutaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134033 chebi_ph7_3 GO:0015380 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015380 GO:0015381 biolink:MolecularActivity high-affinity sulfate transmembrane transporter activity Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations. go-plus.json high affinity sulfate permease activity|high affinity sulfate transmembrane transporter activity|high affinity sulphate permease activity http://purl.obolibrary.org/obo/GO_0015381 GO:0015382 biolink:MolecularActivity sodium:sulfate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in). Reactome:R-HSA-433099|Reactome:R-HSA-433114 go-plus.json sodium:sulphate symporter activity|sodium:sulfate cotransporter activity http://purl.obolibrary.org/obo/GO_0015382 CHEBI:134031 biolink:ChemicalSubstance N-oleoyl-L-serinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134031 chebi_ph7_3 GO:0015383 biolink:MolecularActivity sulfate:bicarbonate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out). go-plus.json sulphate:bicarbonate antiporter activity http://purl.obolibrary.org/obo/GO_0015383 GO:0030998 biolink:CellularComponent linear element A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex. go-plus.json http://purl.obolibrary.org/obo/GO_0030998 GO:0030999 biolink:BiologicalProcess linear element assembly The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex. go-plus.json linear element formation http://purl.obolibrary.org/obo/GO_0030999 GO:0030996 biolink:BiologicalProcess obsolete mitotic cell cycle arrest in response to nitrogen starvation OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen. go-plus.json cell cycle arrest in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_0030996 GO:0030997 biolink:BiologicalProcess regulation of centriole-centriole cohesion Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker. go-plus.json http://purl.obolibrary.org/obo/GO_0030997 GO:0030994 biolink:BiologicalProcess primary cell septum disassembly Dissolution of the primary septum during cell separation. go-plus.json hydrolysis of primary cell septum|primary cell septum hydrolysis|primary septum hydrolysis http://purl.obolibrary.org/obo/GO_0030994 GO:0030995 biolink:BiologicalProcess cell septum edging catabolic process The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation. go-plus.json hydrolysis of edging of cell septum|hydrolysis of cell septum edging|cell septum edging hydrolysis|septum edging hydrolysis http://purl.obolibrary.org/obo/GO_0030995 GO:0015359 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015359 CHEBI:134004 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134004 CHEBI:134005 biolink:ChemicalSubstance alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134005 CHEBI:134002 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134002 CHEBI:134003 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134003 GO:0015355 biolink:MolecularActivity secondary active monocarboxylate transmembrane transporter activity Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism. go-plus.json monocarboxylate porter activity http://purl.obolibrary.org/obo/GO_0015355 GO:0015356 biolink:MolecularActivity obsolete monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity http://purl.obolibrary.org/obo/GO_0015356 GO:0015357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015357 GO:0015358 biolink:MolecularActivity obsolete amino acid/choline transmembrane transporter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json amino acid/choline transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015358 GO:0030992 biolink:CellularComponent intraciliary transport particle B The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa. go-plus.json IFT complex B|IFT B complex|intraflagellar transport particle B|intraflagellar transport complex B http://purl.obolibrary.org/obo/GO_0030992 GO:0015351 biolink:MolecularActivity bilirubin secondary active transmembrane transporter activity Enables the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json bilitranslocase|bilirubin porter activity http://purl.obolibrary.org/obo/GO_0015351 GO:0015352 biolink:MolecularActivity obsolete secondary active sterol transmembrane transporter activity OBSOLETE. Enables the transfer of sterol from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. go-plus.json sterol porter activity http://purl.obolibrary.org/obo/GO_0015352 GO:0030993 biolink:CellularComponent axonemal heterotrimeric kinesin-II complex A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme. go-plus.json http://purl.obolibrary.org/obo/GO_0030993 GO:0030990 biolink:CellularComponent intraciliary transport particle A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. go-plus.json IFT complex|intraflagellar transport particle|intraflagellar transport complex http://purl.obolibrary.org/obo/GO_0030990 goslim_pir GO:0015353 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015353 GO:0030991 biolink:CellularComponent intraciliary transport particle A The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa. go-plus.json IFT A complex|IFT complex A|intraflagellar transport particle A|intraflagellar transport complex A http://purl.obolibrary.org/obo/GO_0030991 GO:0015354 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015354 CHEBI:134000 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134000 CHEBI:134001 biolink:ChemicalSubstance norbelladine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134001 chebi_ph7_3 GO:0015350 biolink:MolecularActivity methotrexate transmembrane transporter activity Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase. go-plus.json methotrexate transporter activity http://purl.obolibrary.org/obo/GO_0015350 GO:0030989 biolink:BiologicalProcess dynein-driven meiotic oscillatory nuclear movement Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein. go-plus.json horsetail nuclear movement|HNM|horsetail movement http://purl.obolibrary.org/obo/GO_0030989 GO:0030987 biolink:MolecularActivity high molecular weight kininogen receptor binding Binding to a high molecular weight kininogen receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0030987 GO:0030988 biolink:CellularComponent high molecular weight kininogen receptor complex A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030988 GO:0030985 biolink:MolecularActivity high molecular weight kininogen binding Binding to a kininogen of high molecular mass. go-plus.json HMW kininogen binding|HK binding http://purl.obolibrary.org/obo/GO_0030985 GO:0030986 biolink:MolecularActivity low molecular weight kininogen binding Binding to a kininogen of low molecular mass. go-plus.json LMW kininogen binding|LK binding http://purl.obolibrary.org/obo/GO_0030986 GO:0030983 biolink:MolecularActivity mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches. go-plus.json mispair binding|mispaired DNA binding http://purl.obolibrary.org/obo/GO_0030983 GO:0030984 biolink:MolecularActivity kininogen binding Binding to a kininogen, a kinin precursor. go-plus.json http://purl.obolibrary.org/obo/GO_0030984 GO:0015366 biolink:MolecularActivity malate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in). go-plus.json malate:hydrogen symporter activity|L-malic acid:proton symporter activity|malate permease|L-malic acid permease http://purl.obolibrary.org/obo/GO_0015366 CHEBI:134019 biolink:ChemicalSubstance hydroperoxy polyunsaturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134019 chebi_ph7_3 GO:0015367 biolink:MolecularActivity oxoglutarate:malate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out). Reactome:R-HSA-376851|Reactome:R-HSA-198440 go-plus.json 2-oxoglutarate/malate carrier protein http://purl.obolibrary.org/obo/GO_0015367 GO:0015368 biolink:MolecularActivity calcium:cation antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in). Reactome:R-HSA-425822 go-plus.json http://purl.obolibrary.org/obo/GO_0015368 CHEBI:134017 biolink:ChemicalSubstance 11a-hydroxytetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_134017 CHEBI:134018 biolink:ChemicalSubstance N-acyl-gamma-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134018 GO:0015369 biolink:MolecularActivity calcium:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in). Reactome:R-HSA-8949687|RHEA:29671 go-plus.json calcium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015369 GO:0015362 biolink:MolecularActivity high-affinity sodium:dicarboxylate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Reactome:R-HSA-433101 go-plus.json high affinity sodium:dicarboxylate cotransporter activity|high affinity sodium:dicarboxylate symporter activity http://purl.obolibrary.org/obo/GO_0015362 GO:0030981 biolink:CellularComponent cortical microtubule cytoskeleton The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0030981 GO:0030982 biolink:BiologicalProcess adventurous gliding motility A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime. go-plus.json adventurous gliding movement http://purl.obolibrary.org/obo/GO_0030982 GO:0015363 biolink:MolecularActivity obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json dicarboxylate (succinate/fumarate/malate) antiporter activity http://purl.obolibrary.org/obo/GO_0015363 GO:0015364 biolink:MolecularActivity dicarboxylate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015364 GO:0030980 biolink:BiologicalProcess alpha-glucan catabolic process The chemical reactions and pathways resulting in the breakdown of alpha-glucans. go-plus.json alpha-glucan degradation|alpha-glucan breakdown|alpha-glucan catabolism http://purl.obolibrary.org/obo/GO_0030980 GO:0015365 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015365 GO:0015360 biolink:MolecularActivity acetate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in). go-plus.json hydrogen:acetate symporter activity|acetate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015360 GO:0015361 biolink:MolecularActivity low-affinity sodium:dicarboxylate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Reactome:R-HSA-433131 go-plus.json low affinity sodium:dicarboxylate cotransporter activity|low affinity sodium:dicarboxylate symporter activity http://purl.obolibrary.org/obo/GO_0015361 GO:0030978 biolink:BiologicalProcess alpha-glucan metabolic process The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds. go-plus.json alpha-glucan metabolism http://purl.obolibrary.org/obo/GO_0030978 GO:0030979 biolink:BiologicalProcess alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds. go-plus.json alpha-glucan anabolism|alpha-glucan synthesis|alpha-glucan formation|alpha-glucan biosynthesis http://purl.obolibrary.org/obo/GO_0030979 GO:0030976 biolink:MolecularActivity thiamine pyrophosphate binding Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases. go-plus.json aneurine pyrophosphate binding|thiamin pyrophosphate binding|cocarboxylase binding|TPP binding|diphosphothiamin binding http://purl.obolibrary.org/obo/GO_0030976 GO:0030977 biolink:MolecularActivity taurine binding Binding to taurine. go-plus.json http://purl.obolibrary.org/obo/GO_0030977 GO:0030974 biolink:BiologicalProcess thiamine pyrophosphate transmembrane transport The process in which thiamine pyrophosphate is transported across a membrane. go-plus.json thiamin diphosphate transport|thiamin pyrophosphate transport|thiamine pyrophosphate transport|thiamine diphosphate transport|TPP transport http://purl.obolibrary.org/obo/GO_0030974 GO:0030975 biolink:MolecularActivity thiamine binding Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. go-plus.json vitamin B1 binding|thiamin binding http://purl.obolibrary.org/obo/GO_0030975 GO:0030972 biolink:BiologicalProcess obsolete cleavage of cytosolic proteins involved in execution phase of apoptosis OBSOLETE. The proteolytic degradation of proteins in the cytosol that contributes to apoptosis. go-plus.json cleavage of cytosolic proteins involved in apoptosis|apoptotic cleavage of cytosolic proteins|cleavage of cytosolic proteins involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0030972 GO:0030973 biolink:MolecularActivity molybdate ion binding Binding to a molybdate ion (MoO4 2-). go-plus.json MoO4 ion binding http://purl.obolibrary.org/obo/GO_0030973 GO:0015337 biolink:MolecularActivity obsolete low affinity metal ion uptake transporter activity OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+. go-plus.json low affinity metal ion uptake transporter activity http://purl.obolibrary.org/obo/GO_0015337 GO:0015338 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015338 GO:0015339 biolink:MolecularActivity obsolete cobalt, zinc uptake permease activity OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport. go-plus.json cobalt, zinc uptake permease activity http://purl.obolibrary.org/obo/GO_0015339 GO:0015333 biolink:MolecularActivity peptide:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement. Reactome:R-HSA-427998|RHEA:37047|Reactome:R-HSA-428007 go-plus.json peptide:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015333 GO:0015334 biolink:MolecularActivity high-affinity oligopeptide transmembrane transporter activity Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. go-plus.json high-affinity oligopeptide transporter activity|high affinity oligopeptide transporter activity http://purl.obolibrary.org/obo/GO_0015334 GO:0015335 biolink:MolecularActivity obsolete heavy metal ion:hydrogen symporter activity OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+. go-plus.json heavy metal ion:proton symporter activity|heavy metal ion:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015335 GO:0015336 biolink:MolecularActivity obsolete high affinity metal ion uptake transporter activity OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+. go-plus.json high affinity metal ion uptake transporter activity http://purl.obolibrary.org/obo/GO_0015336 GO:0030970 biolink:BiologicalProcess retrograde protein transport, ER to cytosol The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon. go-plus.json protein dislocation from ER|retrograde protein transport, endoplasmic reticulum to cytosol|protein retrotranslocation, ER to cytosol http://purl.obolibrary.org/obo/GO_0030970 GO:0030971 biolink:MolecularActivity receptor tyrosine kinase binding Binding to a receptor that possesses protein tyrosine kinase activity. go-plus.json transmembrane receptor protein tyrosine kinase ligand binding http://purl.obolibrary.org/obo/GO_0030971 GO:0015330 biolink:MolecularActivity high-affinity glutamine transmembrane transporter activity Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity glutamine transmembrane transporter activity|high affinity glutamine permease activity http://purl.obolibrary.org/obo/GO_0015330 GO:0015331 biolink:MolecularActivity obsolete asparagine/glutamine permease activity OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane. go-plus.json asparagine/glutamine permease activity http://purl.obolibrary.org/obo/GO_0015331 GO:0015332 biolink:MolecularActivity obsolete leucine/valine/isoleucine permease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json leucine/valine/isoleucine permease activity http://purl.obolibrary.org/obo/GO_0015332 GO:0030967 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030967 GO:0030968 biolink:BiologicalProcess endoplasmic reticulum unfolded protein response The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. go-plus.json SREBP-mediated signalling pathway|ER unfolded protein response|erUPR http://purl.obolibrary.org/obo/GO_0030968 GO:0030965 biolink:BiologicalProcess plasma membrane electron transport, NADH to quinone The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase. go-plus.json http://purl.obolibrary.org/obo/GO_0030965 GO:0030966 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030966 GO:0030963 biolink:BiologicalProcess peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine. RESID:AA0370 go-plus.json http://purl.obolibrary.org/obo/GO_0030963 GO:0030964 biolink:CellularComponent NADH dehydrogenase complex An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone. Wikipedia:NADH_dehydrogenase go-plus.json NADH dehydrogenase complex (plastoquinone)|plastid NADH dehydrogenase complex (plastoquinone)|Complex I|NADH dehydrogenase complex (quinone)|NADH dehydrogenase complex (ubiquinone)|NADH:plastoquinone reductase complex http://purl.obolibrary.org/obo/GO_0030964 goslim_pir GO:0030961 biolink:BiologicalProcess peptidyl-arginine hydroxylation The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine. go-plus.json http://purl.obolibrary.org/obo/GO_0030961 GO:0030962 biolink:BiologicalProcess peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine. RESID:AA0369 go-plus.json http://purl.obolibrary.org/obo/GO_0030962 CHEBI:42266 biolink:ChemicalSubstance ethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_42266 chebi_ph7_3 GO:0030969 biolink:BiologicalProcess obsolete mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response OBSOLETE. The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes. go-plus.json UFP-specific transcription factor mRNA processing involved in ER UPR|unconventional mRNA splicing involved in UPR|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response|XBP1 mRNA splicing, via endonucleolytic cleavage and ligation|XBP1 mRNA splicing under conditions of endoplasmic reticulum (ER) stress|UFP-specific transcription factor mRNA processing during unfolded protein response|unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase|unconventional splicing of XBP1 mRNA|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum UPR|UFP-specific transcription factor mRNA processing involved in ER unfolded protein response|HAC1 mRNA splicing|non-spliceosomal mRNA splicing in the unfolded protein response pathway|unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor|IRE1-mediated XBP-1 mRNA splicing|Ire1p-mediated HAC-1 mRNA splicing|XBP1 mRNA splicing|spliceosome-independent UFP-specific transcription factor mRNA processing http://purl.obolibrary.org/obo/GO_0030969 GO:0015348 biolink:MolecularActivity obsolete prostaglandin/thromboxane transporter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json prostaglandin/thromboxane transporter activity http://purl.obolibrary.org/obo/GO_0015348 GO:0015349 biolink:MolecularActivity thyroid hormone transmembrane transporter activity Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. Reactome:R-HSA-9631987|Reactome:R-HSA-879575 go-plus.json http://purl.obolibrary.org/obo/GO_0015349 GO:0015344 biolink:MolecularActivity siderophore uptake transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in). go-plus.json ferrioxamine uptake transmembrane transporter activity|siderophore-iron uptake transmembrane transporter activity|siderochrome-iron (ferrioxamine) uptake transporter http://purl.obolibrary.org/obo/GO_0015344 GO:0015345 biolink:MolecularActivity ferric enterobactin:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in). go-plus.json ferric-enterobactin:proton symporter activity|ferric enterobactin:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015345 GO:0015346 biolink:MolecularActivity ferric triacetylfusarinine C:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in). go-plus.json ferric triacetylfusarinine C:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015346 GO:0015347 biolink:MolecularActivity sodium-independent organic anion transmembrane transporter activity Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner. Reactome:R-HSA-561059|Reactome:R-HSA-879584|Reactome:R-HSA-879594|Reactome:R-HSA-9661723|Reactome:R-HSA-9661799|Reactome:R-HSA-9661397|Reactome:R-HSA-879562|Reactome:R-HSA-9661446 go-plus.json http://purl.obolibrary.org/obo/GO_0015347 GO:0015340 biolink:MolecularActivity obsolete zinc, cadmium uptake permease activity OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport. go-plus.json zinc, cadmium uptake permease activity http://purl.obolibrary.org/obo/GO_0015340 GO:0030960 biolink:BiologicalProcess peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link. RESID:AA0368 go-plus.json http://purl.obolibrary.org/obo/GO_0030960 GO:0015341 biolink:MolecularActivity zinc efflux active transmembrane transporter activity Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force. go-plus.json zinc efflux permease activity http://purl.obolibrary.org/obo/GO_0015341 GO:0015342 biolink:MolecularActivity obsolete zinc, iron permease activity OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force. go-plus.json zinc, iron permease activity http://purl.obolibrary.org/obo/GO_0015342 CHEBI:17299 biolink:ChemicalSubstance 4-methylene-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17299 GO:0015343 biolink:MolecularActivity siderophore transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in). Reactome:R-HSA-1222597 go-plus.json siderophore transporter activity|siderophore-iron transmembrane transporter activity|siderochrome-iron transporter activity|siderophore-iron transporter activity|siderochrome transporter activity|iron-siderophore transporter activity http://purl.obolibrary.org/obo/GO_0015343 CHEBI:17297 biolink:ChemicalSubstance UDP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_17297 CHEBI:17298 biolink:ChemicalSubstance dolichyl D-xylosyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17298 CHEBI:17295 biolink:ChemicalSubstance L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17295 CHEBI:17296 biolink:ChemicalSubstance aniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_17296 chebi_ph7_3 GO:0030956 biolink:CellularComponent glutamyl-tRNA(Gln) amidotransferase complex A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms. go-plus.json GatFAB|GatCAB|AdT http://purl.obolibrary.org/obo/GO_0030956 GO:0030957 biolink:MolecularActivity Tat protein binding Binding to Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus. go-plus.json http://purl.obolibrary.org/obo/GO_0030957 GO:0005998 biolink:BiologicalProcess xylulose catabolic process The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose. MetaCyc:XYLCAT-PWY go-plus.json xylulose breakdown|xylulose catabolism|xylulose degradation http://purl.obolibrary.org/obo/GO_0005998 GO:0030954 biolink:BiologicalProcess astral microtubule nucleation The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0030954 GO:0030955 biolink:MolecularActivity potassium ion binding Binding to a potassium ion (K+). go-plus.json K ion binding http://purl.obolibrary.org/obo/GO_0030955 GO:0005999 biolink:BiologicalProcess xylulose biosynthetic process The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose. go-plus.json xylulose anabolism|xylulose synthesis|xylulose formation|xylulose biosynthesis http://purl.obolibrary.org/obo/GO_0005999 GO:0030952 biolink:BiologicalProcess establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. go-plus.json cytoskeleton polarization http://purl.obolibrary.org/obo/GO_0030952 GO:0005996 biolink:BiologicalProcess monosaccharide metabolic process The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. go-plus.json monosaccharide metabolism http://purl.obolibrary.org/obo/GO_0005996 GO:0005997 biolink:BiologicalProcess xylulose metabolic process The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose. go-plus.json xylulose metabolism http://purl.obolibrary.org/obo/GO_0005997 GO:0030953 biolink:BiologicalProcess astral microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles. go-plus.json astral microtubule organization and biogenesis|astral microtubule organisation http://purl.obolibrary.org/obo/GO_0030953 GO:0030950 biolink:BiologicalProcess establishment or maintenance of actin cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures. go-plus.json http://purl.obolibrary.org/obo/GO_0030950 GO:0005994 biolink:BiologicalProcess melibiose metabolic process The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. go-plus.json melibiose metabolism http://purl.obolibrary.org/obo/GO_0005994 GO:0005995 biolink:BiologicalProcess melibiose catabolic process The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. go-plus.json melibiose degradation|melibiose catabolism|melibiose breakdown http://purl.obolibrary.org/obo/GO_0005995 GO:0030951 biolink:BiologicalProcess establishment or maintenance of microtubule cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. go-plus.json http://purl.obolibrary.org/obo/GO_0030951 GO:0005992 biolink:BiologicalProcess trehalose biosynthetic process The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. MetaCyc:TRESYN-PWY|MetaCyc:TREHALOSESYN-PWY|MetaCyc:PWY-881 go-plus.json trehalose biosynthesis|trehalose anabolism|mykose biosynthetic process|mykose biosynthesis|trehalose synthesis|trehalose formation|mycose biosynthetic process|mycose biosynthesis http://purl.obolibrary.org/obo/GO_0005992 GO:0005993 biolink:BiologicalProcess trehalose catabolic process The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. MetaCyc:TREDEGLOW-PWY go-plus.json mykose catabolic process|trehalose degradation|trehalose catabolism|trehalose breakdown|mykose catabolism|mycose catabolic process|mycose catabolism http://purl.obolibrary.org/obo/GO_0005993 GO:0005990 biolink:BiologicalProcess lactose catabolic process The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose. go-plus.json lactose breakdown|lactose catabolism|lactose degradation http://purl.obolibrary.org/obo/GO_0005990 CHEBI:42255 biolink:ChemicalSubstance (-)-epigallocatechin go-plus.json http://purl.obolibrary.org/obo/CHEBI_42255 chebi_ph7_3 GO:0005991 biolink:BiologicalProcess trehalose metabolic process The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. go-plus.json mycose metabolism|trehalose metabolism|mycose metabolic process|mykose metabolism|mykose metabolic process http://purl.obolibrary.org/obo/GO_0005991 GO:0015319 biolink:MolecularActivity sodium:inorganic phosphate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015319 GO:0030958 biolink:CellularComponent RITS complex A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing. go-plus.json http://purl.obolibrary.org/obo/GO_0030958 GO:0030959 biolink:BiologicalProcess peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link. RESID:AA0367 go-plus.json http://purl.obolibrary.org/obo/GO_0030959 GO:0015315 biolink:MolecularActivity organophosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015315 GO:0015316 biolink:MolecularActivity obsolete nitrite/nitrate porter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json nitrite/nitrate porter activity http://purl.obolibrary.org/obo/GO_0015316 GO:0015317 biolink:MolecularActivity phosphate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in). go-plus.json phosphate ion carrier activity|phosphate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015317 GO:0015318 biolink:MolecularActivity inorganic molecular entity transmembrane transporter activity Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon. go-plus.json inorganic uptake permease activity|inorganic solute uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015318 gocheck_do_not_annotate GO:0015311 biolink:MolecularActivity monoamine:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out). go-plus.json monoamine:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015311 GO:0015312 biolink:MolecularActivity polyamine:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out). go-plus.json polyamine:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015312 GO:0015313 biolink:MolecularActivity fluconazole:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out). go-plus.json fluconazole:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015313 GO:0015314 biolink:MolecularActivity aminotriazole:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out). go-plus.json aminotriazole:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015314 GO:0015310 biolink:MolecularActivity benomyl:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out). go-plus.json benomyl:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015310 GO:0030945 biolink:MolecularActivity protein tyrosine phosphatase activity, via thiol-phosphate intermediate The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0030945 GO:0030946 biolink:MolecularActivity protein tyrosine phosphatase activity, metal-dependent Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions. go-plus.json http://purl.obolibrary.org/obo/GO_0030946 GO:0030943 biolink:MolecularActivity mitochondrion targeting sequence binding Binding to a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion. go-plus.json mitochondrial targeting sequence binding http://purl.obolibrary.org/obo/GO_0030943 GO:0030944 biolink:MolecularActivity DDEL sequence binding Binding to a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0030944 GO:0030941 biolink:MolecularActivity chloroplast targeting sequence binding Binding to a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0030941 GO:0030942 biolink:MolecularActivity endoplasmic reticulum signal peptide binding Binding to an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum. go-plus.json ER signal peptide binding http://purl.obolibrary.org/obo/GO_0030942 GO:0030940 biolink:BiologicalProcess obsolete response to short-day photoperiod OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the dark phase being longer than the light. go-plus.json response to short-day photoperiod http://purl.obolibrary.org/obo/GO_0030940 GO:0030949 biolink:BiologicalProcess positive regulation of vascular endothelial growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. go-plus.json up regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signaling pathway|positive regulation of vascular endothelial growth factor receptor signalling pathway|activation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signalling pathway|stimulation of vascular endothelial growth factor receptor signaling pathway|up-regulation of vascular endothelial growth factor receptor signaling pathway|upregulation of vascular endothelial growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030949 GO:0030947 biolink:BiologicalProcess regulation of vascular endothelial growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. go-plus.json regulation of VEGF receptor signaling pathway|regulation of vascular endothelial growth factor receptor signalling pathway|regulation of VEGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0030947 GO:0030948 biolink:BiologicalProcess negative regulation of vascular endothelial growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. go-plus.json down regulation of vascular endothelial growth factor receptor signaling pathway|downregulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of vascular endothelial growth factor receptor signalling pathway|negative regulation of VEGF receptor signalling pathway|negative regulation of VEGF receptor signaling pathway|down-regulation of vascular endothelial growth factor receptor signaling pathway|inhibition of vascular endothelial growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030948 GO:0015326 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015326 GO:0015327 biolink:MolecularActivity cystine:glutamate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015327 GO:0015328 biolink:MolecularActivity cystine secondary active transmembrane transporter activity Enables the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json lysosomal cystine transporter|cystinosin|cystine porter activity http://purl.obolibrary.org/obo/GO_0015328 GO:0015329 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015329 GO:0015322 biolink:MolecularActivity secondary active oligopeptide transmembrane transporter activity Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. go-plus.json oligopeptide porter activity http://purl.obolibrary.org/obo/GO_0015322 GO:0015323 biolink:MolecularActivity obsolete type V protein secretor activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json type V protein secretor activity http://purl.obolibrary.org/obo/GO_0015323 GO:0015324 biolink:MolecularActivity peptide-acetyl-CoA secondary active transmembrane transporter activity Enables the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json peptide-acetyl-CoA transporter activity http://purl.obolibrary.org/obo/GO_0015324 GO:0015325 biolink:MolecularActivity acetyl-CoA:CoA antiporter activity Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015325 GO:0015320 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015320 GO:0015321 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015321 CHEBI:27405 biolink:ChemicalSubstance streptidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27405 CHEBI:27406 biolink:ChemicalSubstance indole-5,6-quinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27406 chebi_ph7_3 CHEBI:27402 biolink:ChemicalSubstance (S)-3-hydroxypalmitoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27402 CHEBI:27404 biolink:ChemicalSubstance 5,6-dihydroxyindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_27404 chebi_ph7_3 UBERON:0019042 biolink:AnatomicalEntity reproductive system mucosa go-plus.json genital mucosa http://purl.obolibrary.org/obo/UBERON_0019042 NCBITaxon:5702 biolink:OrganismalEntity Trypanosoma brucei brucei go-plus.json Trypanosoma (Trypanozoon) brucei brucei|Trypanosoma brucei subsp. brucei http://purl.obolibrary.org/obo/NCBITaxon_5702 UBERON:0034670 biolink:AnatomicalEntity palatal taste bud A taste bud that is located on the soft palate, in the roof of the mouth. go-plus.json taste bud of palate http://purl.obolibrary.org/obo/UBERON_0034670 UBERON:0034681 biolink:AnatomicalEntity vocal organ Any organ that is the primary organ of vocalization behavior. Examples: The laryngeal vocal cord (humans), the syrinx (birds). go-plus.json http://purl.obolibrary.org/obo/UBERON_0034681 NCBITaxon:5719 biolink:OrganismalEntity Parabasalia go-plus.json parabasalians|parabasalids|Parabasalidea http://purl.obolibrary.org/obo/NCBITaxon_5719 CHEBI:27479 biolink:ChemicalSubstance 2'-hydroxydaidzein go-plus.json http://purl.obolibrary.org/obo/CHEBI_27479 NCBITaxon:5741 biolink:OrganismalEntity Giardia intestinalis go-plus.json Giardia lamblia|Giardia duodenalis|Lamblia intestinalis http://purl.obolibrary.org/obo/NCBITaxon_5741 CHEBI:27475 biolink:ChemicalSubstance cyanidin 3-O-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27475 CL:0000525 biolink:Cell syncytiotrophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. go-plus.json syntrophoblast|plasmidotrophoblast|syncytial trophoblast http://purl.obolibrary.org/obo/CL_0000525 CHEBI:27476 biolink:ChemicalSubstance beta-D-ribopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27476 chebi_ph7_3 CL:0000526 biolink:Cell afferent neuron A neuron which conveys sensory information centrally from the periphery. go-plus.json input neuron http://purl.obolibrary.org/obo/CL_0000526 CHEBI:27477 biolink:ChemicalSubstance D-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27477 CL:0000527 biolink:Cell efferent neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. go-plus.json output neuron http://purl.obolibrary.org/obo/CL_0000527 CHEBI:27470 biolink:ChemicalSubstance folic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27470 CHEBI:27471 biolink:ChemicalSubstance glycodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27471 UBERON:0009678 biolink:AnatomicalEntity tooth row Anatomical cluster consisting of adjacent teeth constituting a row. go-plus.json tooth rows|row of teeth|dental arcade http://purl.obolibrary.org/obo/UBERON_0009678 UBERON:0009679 biolink:AnatomicalEntity set of lower jaw teeth A tooth row that is part of a skeleton of lower jaw. go-plus.json arcus dentalis inferior|lower jaw teeth|mandibular dental arcade|lower dental arcade|set of all lower teeth http://purl.obolibrary.org/obo/UBERON_0009679 CHEBI:27480 biolink:ChemicalSubstance phenylacetylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27480 CL:0000520 biolink:Cell prokaryotic cell go-plus.json http://purl.obolibrary.org/obo/CL_0000520 CL:0000521 biolink:Cell fungal cell go-plus.json http://purl.obolibrary.org/obo/CL_0000521 UBERON:0009670 biolink:AnatomicalEntity rectal lumen An anatomical space that surrounded_by a rectum. go-plus.json lumen of rectum http://purl.obolibrary.org/obo/UBERON_0009670 CHEBI:52430 biolink:ChemicalSubstance N-malonylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52430 CHEBI:52432 biolink:ChemicalSubstance (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52432 UBERON:0009676 biolink:AnatomicalEntity early telencephalic vesicle go-plus.json early telencephalic ventricle|early telencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0009676 NCBITaxon:5758 biolink:OrganismalEntity Entamoeba go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5758 NCBITaxon:5759 biolink:OrganismalEntity Entamoeba histolytica go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5759 CHEBI:52424 biolink:ChemicalSubstance EC 3.2.1.* (glycosidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_52424 CHEBI:52425 biolink:ChemicalSubstance EC 3.2.1.18 (exo-alpha-sialidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_52425 CHEBI:52426 biolink:ChemicalSubstance 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52426 CHEBI:27485 biolink:ChemicalSubstance prostaglandin J2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27485 CHEBI:27487 biolink:ChemicalSubstance 3-(imidazol-5-yl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27487 CHEBI:27482 biolink:ChemicalSubstance (R)-coclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27482 UBERON:0009668 biolink:AnatomicalEntity ventral mesentery Ventral mesentery is the part of the peritoneum closest to the navel. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009668 UBERON:0009669 biolink:AnatomicalEntity embryonic cloacal lumen An anatomical space that surrounded_by a embryonic cloaca. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009669 CHEBI:27491 biolink:ChemicalSubstance leukotriene F4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27491 CL:0000530 biolink:Cell primary neuron go-plus.json http://purl.obolibrary.org/obo/CL_0000530 CL:0000531 biolink:Cell primary sensory neuron go-plus.json http://purl.obolibrary.org/obo/CL_0000531 CHEBI:52421 biolink:ChemicalSubstance 3-oxohexacosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52421 UBERON:0009661 biolink:AnatomicalEntity midbrain nucleus Nucleus located in the midbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009661 UBERON:0009662 biolink:AnatomicalEntity hindbrain nucleus Nucleus located within the hindbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009662 UBERON:0009663 biolink:AnatomicalEntity telencephalic nucleus A nucleus of brain that is part of a telencephalon. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009663 UBERON:0009664 biolink:AnatomicalEntity gut mesentery go-plus.json peritoneal cavity mesentary|peritoneal mesentary http://purl.obolibrary.org/obo/UBERON_0009664 CHEBI:52417 biolink:ChemicalSubstance D-glucosone go-plus.json http://purl.obolibrary.org/obo/CHEBI_52417 chebi_ph7_3 NCBITaxon:5721 biolink:OrganismalEntity Trichomonas go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5721 NCBITaxon:5722 biolink:OrganismalEntity Trichomonas vaginalis go-plus.json Tritrichomonas vaginalis http://purl.obolibrary.org/obo/NCBITaxon_5722 CHEBI:27457 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)5-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27457 CHEBI:27458 biolink:ChemicalSubstance 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27458 CHEBI:27452 biolink:ChemicalSubstance styrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27452 chebi_ph7_3 CL:0000501 biolink:Cell granulosa cell A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. go-plus.json granulosa cell of ovary http://purl.obolibrary.org/obo/CL_0000501 CHEBI:27453 biolink:ChemicalSubstance 3-keto-beta-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27453 chebi_ph7_3 CL:0000502 biolink:Cell type D enteroendocrine cell A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. go-plus.json D cell http://purl.obolibrary.org/obo/CL_0000502 CHEBI:27450 biolink:ChemicalSubstance 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27450 UBERON:0009657 biolink:AnatomicalEntity artery of lip go-plus.json labial artery http://purl.obolibrary.org/obo/UBERON_0009657 UBERON:0009651 biolink:AnatomicalEntity nephron tubule basement membrane A basement membrane that is part of a nephron tubule. go-plus.json kidney tubule basement membrane|renal tubular basement membrane|renal tubule basement membrane http://purl.obolibrary.org/obo/UBERON_0009651 UBERON:0009652 biolink:AnatomicalEntity bronchus basement membrane A basement membrane that is part of a bronchus. go-plus.json bronchial basement membrane http://purl.obolibrary.org/obo/UBERON_0009652 UBERON:0009653 biolink:AnatomicalEntity trachea basement membrane A basement membrane that is part of a trachea. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009653 UBERON:0009655 biolink:AnatomicalEntity auricular artery An artery that supplies oxygenated blood to the ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009655 CHEBI:52402 biolink:ChemicalSubstance 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_52402 CHEBI:27468 biolink:ChemicalSubstance 5,6-dihydrothymine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27468 chebi_ph7_3 CHEBI:27469 biolink:ChemicalSubstance 2-dehydro-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27469 CL:0000513 biolink:Cell cardiac muscle myoblast A precursor cell destined to differentiate into cardiac muscle cell. go-plus.json cardiac muscle progenitor cell|cardiomyocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000513 CL:0000514 biolink:Cell smooth muscle myoblast A precursor cell destined to differentiate into smooth muscle myocytes. go-plus.json myoblast, smooth muscle|satellite cell http://purl.obolibrary.org/obo/CL_0000514 CL:0000515 biolink:Cell skeletal muscle myoblast A myoblast that differentiates into skeletal muscle fibers. go-plus.json skeletal myoblast http://purl.obolibrary.org/obo/CL_0000515 CHEBI:27466 biolink:ChemicalSubstance (S)-3-hydroxytetradecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27466 NCBITaxon:40674 biolink:OrganismalEntity Mammalia go-plus.json mammals|mammals http://purl.obolibrary.org/obo/NCBITaxon_40674 CL:0000517 biolink:Cell macrophage derived foam cell A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/CL_0000517 NCBITaxon:5738 biolink:OrganismalEntity Diplomonadida go-plus.json diplomonads|diplomonads http://purl.obolibrary.org/obo/NCBITaxon_5738 CL:0000519 biolink:Cell phagocyte (sensu Nematoda and Protostomia) A phagocyte from organisms in the Nematoda or Protostomia clades. go-plus.json http://purl.obolibrary.org/obo/CL_0000519 NCBITaxon:5739 biolink:OrganismalEntity Hexamitidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5739 UBERON:0009647 biolink:AnatomicalEntity tympanic membrane epithelium One of the two epithelia which make up the tympanic membrane (along with the fibrous layer) go-plus.json tympanic membrane epithelial layer|tympanic epithelium http://purl.obolibrary.org/obo/UBERON_0009647 UBERON:0009648 biolink:AnatomicalEntity eyelid subcutaneous connective tissue A eyelid connective tissue that is part of a hypodermis. go-plus.json superficial fascia of eyelid http://purl.obolibrary.org/obo/UBERON_0009648 CL:0000511 biolink:Cell androgen binding protein secreting cell A peptide hormone secreting cell that secretes androgen binding protein. go-plus.json http://purl.obolibrary.org/obo/CL_0000511 NCBITaxon:5740 biolink:OrganismalEntity Giardia go-plus.json Giardia http://purl.obolibrary.org/obo/NCBITaxon_5740 UBERON:0009644 biolink:AnatomicalEntity trachea non-cartilage connective tissue go-plus.json http://purl.obolibrary.org/obo/UBERON_0009644 CHEBI:27439 biolink:ChemicalSubstance (KDO)-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27439 NCBITaxon:5786 biolink:OrganismalEntity Dictyostelium purpureum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5786 CHEBI:27432 biolink:ChemicalSubstance alpha-linolenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27432 UBERON:0010698 biolink:AnatomicalEntity manual digit metacarpus pre-cartilage condensation go-plus.json hand digit metacarpus pre-cartilage condensation|metacarpus pre-cartilage condensation|metacarpal pre-cartilage condensation|metacarpal bone pre-cartilage condensation|fore limb digit metacarpus pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010698 UBERON:0010699 biolink:AnatomicalEntity manual digit metacarpus cartilage element go-plus.json metacarpus cartilage element|fore limb digit metacarpus cartilage element|finger metacarpus cartilage element|metacarpal cartilage element|hand digit metacarpus cartilage element|metacarpal cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010699 NCBITaxon:5794 biolink:OrganismalEntity Apicomplexa go-plus.json apicomplexans|apicomplexans http://purl.obolibrary.org/obo/NCBITaxon_5794 CHEBI:27445 biolink:ChemicalSubstance maltohexaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27445 chebi_ph7_3 CHEBI:27442 biolink:ChemicalSubstance beta-D-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27442 chebi_ph7_3 CHEBI:27444 biolink:ChemicalSubstance but-3-yn-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27444 chebi_ph7_3 UBERON:0010696 biolink:AnatomicalEntity skeleton of pedal acropodium The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the pedal autopodium - i.e. the bones of the foot or their cartilaginous precursors[cjm]. go-plus.json phalanges of foot|set of phalanges of pes|posterior acropodium|set of pedal phalanges|foot digit skeleton|posterior acropodium skeleton|set of phalanges of foot|phalanges of pes|hind acropodium skeleton|all phalanges in hindlimb autopod|pedal phalanges http://purl.obolibrary.org/obo/UBERON_0010696 UBERON:0010697 biolink:AnatomicalEntity pedal digit metatarsal cartilage element go-plus.json hind limb digit metatarsal cartilage condensation|foot digit metatarsal cartilage condensation|metatarsal cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010697 UBERON:0010695 biolink:AnatomicalEntity mesenchyme of tarsal region Mesenchyme of the carpal region that contributes to the tarsal skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010695 UBERON:0010687 biolink:AnatomicalEntity pedal digit metatarsal pre-cartilage condensation go-plus.json metatarsus pre-cartilage condensation|hind limb digit metatarsal pre-cartilage condensation|foot digit metatarsal pre-cartilage condensation|metatarsal pre-cartilage condensation|metatarsal bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010687 UBERON:0010688 biolink:AnatomicalEntity skeleton of manual acropodium The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the manual autopodium - i.e. the bones of the hands or their cartilaginous precursors[VSAO,modified]. go-plus.json fore acropodium skeleton|manual phalanges|anterior acropodium skeleton|phalanges of manus|all phalanges in forelimb autopod|anterior acropodium|phalanges of hand|manual digit skeleton|set of manual phalanges|set of phalanges of manus|set of phalanges of hand|hand digit skeleton http://purl.obolibrary.org/obo/UBERON_0010688 CHEBI:27417 biolink:ChemicalSubstance p-xylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27417 chebi_ph7_3 CHEBI:27418 biolink:ChemicalSubstance 1,4-naphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27418 chebi_ph7_3 UBERON:0010685 biolink:AnatomicalEntity pedal digit phalanx cartilage element A cartilage element that is part of a pedal digit mesenchyme. go-plus.json hind limb digit phalanx cartilage condensation|foot digit phalanx cartilage element http://purl.obolibrary.org/obo/UBERON_0010685 UBERON:0010686 biolink:AnatomicalEntity manual digit phalanx cartilage element A cartilage element that is part of a manual digit mesenchyme. go-plus.json fore limb digit phalanx cartilage condensation|hand digit phalanx cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010686 CHEBI:340863 biolink:ChemicalSubstance 2-phospholactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_340863 CHEBI:27427 biolink:ChemicalSubstance 5'-dehydroinosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27427 chebi_ph7_3 CHEBI:27425 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27425 chebi_ph7_3 UBERON:0009680 biolink:AnatomicalEntity set of upper jaw teeth A tooth row that is part of a skeleton of upper jaw. go-plus.json set of all upper teeth|upper dental arcade|maxillary dental arcade|upper jaw teeth|arcus dentalis superior http://purl.obolibrary.org/obo/UBERON_0009680 CHEBI:27422 biolink:ChemicalSubstance (KDO)2-(lauroyl)-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27422 NCBITaxon:5782 biolink:OrganismalEntity Dictyostelium go-plus.json Hyalostilbum http://purl.obolibrary.org/obo/NCBITaxon_5782 GO:1990196 biolink:CellularComponent MacAB-TolC complex The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC. go-plus.json macrolide transporter MacAB-TolC complex http://purl.obolibrary.org/obo/GO_1990196 GO:1990197 biolink:CellularComponent methionine-importing ABC transporter complex An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner. go-plus.json MetNIQ transport complex|ATP-binding cassette (ABC) methionine importer complex|MetNI transport complex|methionine transporter|ATP-dependent methionine-importing complex|methionine transport complex|MetNIQ complex|ATP-dependent methionine importer complex|MetNI complex|MetNIQ transporter|MetNI transporter|methionine transporter complex, ATP-dependent|MetNI transporter complex|ATP-dependent methionine importing complex|methionine transporter complex|MetNIQ transporter complex http://purl.obolibrary.org/obo/GO_1990197 GO:1990198 biolink:CellularComponent ModE complex A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism. go-plus.json ModE dimer http://purl.obolibrary.org/obo/GO_1990198 GO:1990199 biolink:CellularComponent MsbA transporter complex An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD). go-plus.json MsbA dimer|MsbA complex http://purl.obolibrary.org/obo/GO_1990199 UBERON:0009708 biolink:AnatomicalEntity dorsal pancreas go-plus.json pancreatis dorsalis http://purl.obolibrary.org/obo/UBERON_0009708 GO:1990192 biolink:BiologicalProcess collecting lymphatic vessel constriction A decrease in the diameter of collecting lymphatic vessels. go-plus.json lymphatic vessel myogenic constriction http://purl.obolibrary.org/obo/GO_1990192 GO:1990193 biolink:CellularComponent BtuCD complex Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer. go-plus.json vitamin B12 transport complex, core subunit|cobalamin transport complex, core subunit|BtuC-BtuD complex http://purl.obolibrary.org/obo/GO_1990193 UBERON:0009709 biolink:AnatomicalEntity ventral pancreas go-plus.json pancreatis ventralis http://purl.obolibrary.org/obo/UBERON_0009709 GO:1990194 biolink:BiologicalProcess cytoplasmic U snRNP body assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body. go-plus.json U body assembly http://purl.obolibrary.org/obo/GO_1990194 GO:1990195 biolink:CellularComponent macrolide transmembrane transporter complex A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes. go-plus.json MacAB-TolC complex|macrolide transporter complex|AcrAB-TolC complex|macrolide transporter http://purl.obolibrary.org/obo/GO_1990195 GO:0015418 biolink:MolecularActivity ABC-type quaternary ammonium compound transporting activity Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in). MetaCyc:3.6.3.32-RXN|MetaCyc:RXN-8638|EC:7.6.2.9|RHEA:11036 go-plus.json ATPase-coupled quaternary ammonium compound transmembrane transporting activity|quaternary amine uptake transporter activity|quaternary-ammonium-compound ABC transporter|glycine betaine/proline porter activity|ATP-dependent quaternary-ammonium compound transmembrane transporting activity|quaternary-amine-transporting ATPase activity|quarternary amine transporter activity|quaternary-ammonium-compound-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015418 GO:0015419 biolink:MolecularActivity ABC-type sulfate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in). MetaCyc:3.6.3.25-RXN|EC:7.3.2.3|RHEA:10192 go-plus.json sulfate transmembrane-transporting ATPase activity|sulphate transporting ATPase activity|sulfate/thiosulfate porter activity|ATPase-coupled sulfate transmembrane transporter activity|sulfate ABC transporter|sulfate-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015419 GO:1990190 biolink:MolecularActivity peptide-glutamate-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide. go-plus.json http://purl.obolibrary.org/obo/GO_1990190 GO:1990191 biolink:CellularComponent cobalamin transport complex Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD. go-plus.json BtuCDF complex|vitamin B12 transport complex|vitamin B12-transporting BtuCDF complex|cobalamin-transporting BtuCDF complex http://purl.obolibrary.org/obo/GO_1990191 GO:0015414 biolink:MolecularActivity ABC-type nitrate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in). RHEA:13181|MetaCyc:3.6.3.26-RXN|EC:7.3.2.4 go-plus.json nitrate-transporting ATPase activity|nitrate transmembrane-transporting ATPase activity|nitrate transporting ATPase activity|ATPase-coupled nitrate transmembrane transporter activity|nitrate ABC transporter http://purl.obolibrary.org/obo/GO_0015414 UBERON:0009712 biolink:AnatomicalEntity endocardium of right ventricle Any endocardium that is part of the right ventricle of the heart. go-plus.json right ventricle endocardium|right ventricle endocardial tissue|endocardial lining of right ventricle|right ventricular endocardium http://purl.obolibrary.org/obo/UBERON_0009712 GO:0015415 biolink:MolecularActivity ATPase-coupled phosphate ion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in). EC:7.3.2.1|RHEA:24440 go-plus.json ABC phosphate transporter activity|ATP phosphohydrolase (phosphate-importing)|phosphate-transporting ATPase activity|phosphate porter activity|phosphate ABC transporter|phosphate ion transmembrane-transporting ATPase activity|phosphate transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015415 GO:0015416 biolink:MolecularActivity ABC-type phosphonate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2). EC:7.3.2.2|MetaCyc:3.6.3.28-RXN|RHEA:18065|MetaCyc:ABC-23-RXN go-plus.json organic phosphonate transmembrane transporter activity|ATPase-coupled alkylphosphonate transmembrane transporter activity|ATPase-coupled organic phosphonate transmembrane transporter activity|alkylphosphonate transmembrane-transporting ATPase activity|phosphonate-transporting ATPase activity|phosphonate ABC transporter|alkylphosphonate transmembrane transporter activity|ATP phosphohydrolase (phosphonate-transporting)|organic phosphonate transmembrane-transporting ATPase activity|alkylphosphonate ABC transporter activity|phosphonate transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015416 UBERON:0009713 biolink:AnatomicalEntity endocardium of left ventricle Any endocardium that is part of the left ventricle of the heart. go-plus.json left ventricle endocardium|left ventricular endocardium|endocardial lining of left ventricle|left ventricle endocardial tissue http://purl.obolibrary.org/obo/UBERON_0009713 UBERON:0009714 biolink:AnatomicalEntity intermaxillary process The primordial mass of tissue formed by the merging of the medial nasal prominences of the embryo; it contributes to the intermaxillary portion of the upper jaw, the prolabial portion of the upper lip, and the primary palate. go-plus.json intermaxillary segment|globular process|globular processes of his http://purl.obolibrary.org/obo/UBERON_0009714 GO:0015417 biolink:MolecularActivity ABC-type polyamine transporter activity Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in). EC:7.6.2.11|MetaCyc:ABC-24-RXN|MetaCyc:3.6.3.31-RXN|RHEA:29999 go-plus.json spermidine porter activity|ATPase-coupled polyamine transmembrane transporter activity|ATP-dependent polyamine transmembrane transporter activity|polyamine porter activity|polyamine-transporting ATPase activity|polyamine-importing ATPase activity|polyamine ABC transporter|spermidine-importing ATPase activity|ATPase-coupled spermidine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015417 CHEBI:52392 biolink:ChemicalSubstance 2-arachidonoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52392 chebi_ph7_3 CHEBI:134542 biolink:ChemicalSubstance oxodocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134542 CHEBI:76360 biolink:ChemicalSubstance (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76360 chebi_ph7_3 GO:0015410 biolink:MolecularActivity ABC-type manganese transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in). RHEA:17365|MetaCyc:3.6.3.35-RXN|Reactome:R-HSA-5692462|EC:7.2.2.5 go-plus.json manganese-transporting ATPase activity|ABC-type Mn(2+) transporter|manganese transmembrane transporter activity, phosphorylative mechanism|manganese ABC transporter|ATP-dependent manganese transmembrane transporter activity|ATPase-coupled manganese transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015410 UBERON:0009715 biolink:AnatomicalEntity stomodeal lumen An anatomical cavity that surrounded_by a stomodeum. go-plus.json lumen of stomodeum|stomatodeal cavity|lumen of stomatodaeum http://purl.obolibrary.org/obo/UBERON_0009715 GO:0015411 biolink:MolecularActivity ABC-type taurine transporter transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in). MetaCyc:3.6.3.36-RXN|MetaCyc:ABC-64-RXN|EC:7.6.2.7|RHEA:14613 go-plus.json taurine-transporting ATPase activity|ATPase-coupled taurine transporter activity|taurine ABC transporter|ATP-dependent taurine transporter activity http://purl.obolibrary.org/obo/GO_0015411 GO:0015412 biolink:MolecularActivity ABC-type molybdate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in). RHEA:22020|MetaCyc:3.6.3.29-RXN|EC:7.3.2.5 go-plus.json molybdate-transporting ATPase activity|molybdate ABC transporter|molybdate transmembrane-transporting ATPase activity|molybdate porter activity|molybdate transporting ATPase activity|ATPase-coupled molybdate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015412 GO:0015413 biolink:MolecularActivity ABC-type nickel transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in). MetaCyc:3.6.3.24-RXN|MetaCyc:ABC-20-RXN|RHEA:15557|EC:7.2.2.11 go-plus.json nickel porter activity|nickel transporting ATPase activity|nickel ABC transporter|ATP-dependent nickel transmembrane transporter activity|ATPase-coupled nickel transmembrane transporter activity|nickel-transporting ATPase activity|nickel ABC transporter activity http://purl.obolibrary.org/obo/GO_0015413 CHEBI:76364 biolink:ChemicalSubstance (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76364 chebi_ph7_3 CHEBI:76368 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76368 chebi_ph7_3 CHEBI:52393 biolink:ChemicalSubstance episterol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_52393 chebi_ph7_3 CHEBI:134540 biolink:ChemicalSubstance N-acylphytosphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134540 CHEBI:52394 biolink:ChemicalSubstance lanosteryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_52394 chebi_ph7_3 CHEBI:76366 biolink:ChemicalSubstance (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76366 chebi_ph7_3 CHEBI:52395 biolink:ChemicalSubstance oxyketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_52395 CHEBI:52396 biolink:ChemicalSubstance alpha-oxyketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_52396 CHEBI:76367 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76367 chebi_ph7_3 GO:0015429 biolink:MolecularActivity obsolete peroxisomal fatty acyl transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json peroxisomal fatty acyl transporter http://purl.obolibrary.org/obo/GO_0015429 GO:0015425 biolink:MolecularActivity ATPase-coupled nonpolar-amino acid transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in). EC:7.4.2.2|TC:3.A.1.4.1|MetaCyc:3.6.3.22-RXN go-plus.json nonpolar-amino-acid-transporting ATPase activity|nonpolar-amino acid ABC transporter|nonpolar amino acid-transporting ATPase activity|ATP-dependent nonpolar-amino acid transporter activity|nonpolar-amino acid-transporting ATPase activity|leucine/isoleucine/valine porter activity http://purl.obolibrary.org/obo/GO_0015425 GO:0015426 biolink:MolecularActivity ATPase-coupled polar amino acid-transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). EC:7.4.2.1|RHEA:14673|MetaCyc:3.6.3.21-RXN go-plus.json polar amino acid uptake transporter activity|polar-amino acid-importing ATPase activity|ATP-dependent polar amino acid-transporter activity|histidine/arginine/lysine/ornithine porter activity|polar-amino acid-transporting ATPase activity|polar-amino acid ABC transporter|polar amino acid-importing ATPase activity|polar-amino-acid-transporting ATPase activity|cystine/diaminopimelate porter activity|histidine permease activity|glutamate/aspartate porter activity http://purl.obolibrary.org/obo/GO_0015426 GO:0015427 biolink:MolecularActivity obsolete ABC-type efflux porter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ABC-type efflux porter activity http://purl.obolibrary.org/obo/GO_0015427 CHEBI:52381 biolink:ChemicalSubstance hexadec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52381 GO:0015428 biolink:MolecularActivity obsolete type I protein secretor activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json type I protein secretor activity http://purl.obolibrary.org/obo/GO_0015428 GO:0015421 biolink:MolecularActivity ABC-type oligopeptide transporter activity Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in). EC:7.4.2.6|Reactome:R-HSA-5223317|RHEA:37271|MetaCyc:3.6.3.23-RXN go-plus.json ABC-type oligopeptide transporter|ATP-dependent oligopeptide transmembrane transporter activity|oligopeptide permease activity|ATPase-coupled oligopeptide transmembrane transporter activity|oligopeptide-transporting ATPase activity|oligopeptide ABC transporter http://purl.obolibrary.org/obo/GO_0015421 GO:0015422 biolink:MolecularActivity ABC-type oligosaccharide transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in). EC:7.5.2.2|MetaCyc:3.6.3.18-RXN go-plus.json ABC-type oligosaccharide transporter|oligosaccharide-transporting ATPase activity|oligosaccharide ABC transporter|ATPase-coupled oligosaccharide transmembrane transporter activity|ATP-dependent oligosaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015422 GO:0015423 biolink:MolecularActivity ABC-type maltose transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in). EC:7.5.2.1|RHEA:22132|MetaCyc:3.6.3.19-RXN go-plus.json ABC-type maltose transporter|ATPase-coupled maltose transmembrane transporter activity|ATP-dependent maltose transmembrane transporter activity|maltooligosaccharide-importing ATPase activity|maltose-transporting ATPase activity|maltose ABC transporter http://purl.obolibrary.org/obo/GO_0015423 GO:0015424 biolink:MolecularActivity ABC-type amino acid transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out). go-plus.json amino acid-exporting ATPase activity|ATP-dependent amino acid transmembrane transporter activity|ATPase-coupled amino acid transmembrane transporter activity|amino acid-importing ATPase activity|amino acid-transporting ATPase activity|amino acid ABC transporter http://purl.obolibrary.org/obo/GO_0015424 CHEBI:52386 biolink:ChemicalSubstance zymosterol intermediate 2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_52386 chebi_ph7_3 CHEBI:76375 biolink:ChemicalSubstance (R)-3-hydroxydocosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76375 chebi_ph7_3 CHEBI:52388 biolink:ChemicalSubstance 4-hydroxymethylzymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52388 chebi_ph7_3 CHEBI:76373 biolink:ChemicalSubstance (R)-3-hydroxyicosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76373 chebi_ph7_3 GO:0015420 biolink:MolecularActivity ABC-type vitamin B12 transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin. Reactome:R-HSA-3000238|MetaCyc:ABC-5-RXN|EC:7.6.2.8|Reactome:R-HSA-3095901|RHEA:17873|Reactome:R-HSA-3315437|MetaCyc:3.6.3.33-RXN go-plus.json vitamin B12 porter activity|cobalamin ABC transporter|cobalamin-transporting ATPase activity|cobalamin porter activity|vitamin B12 ABC transporter activity|ATPase-coupled cobalamin transmembrane transporter activity|vitamin B12-transporting ATPase activity|cobalamin transporter activity|ATP-dependent vitamin B12 transmembrane transporter activity|vitamin B12 transporter activity|ATP-dependent cobalamin transmembrane transporter activity|ATPase-coupled vitamin B12 transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015420 CHEBI:76374 biolink:ChemicalSubstance (R)-3-hydroxystearoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76374 chebi_ph7_3 CHEBI:76377 biolink:ChemicalSubstance (3R)-3-hydroxytetracosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76377 chebi_ph7_3 CHEBI:76378 biolink:ChemicalSubstance (R)-3-hydroxyhexacosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76378 chebi_ph7_3 CHEBI:134529 biolink:ChemicalSubstance omega-(methylthio)-2-oxocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134529 CHEBI:134527 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134527 CL:0000584 biolink:Cell enterocyte An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. go-plus.json http://purl.obolibrary.org/obo/CL_0000584 CHEBI:76382 biolink:ChemicalSubstance (R)-3-hydroxyoctacosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76382 chebi_ph7_3 CHEBI:76383 biolink:ChemicalSubstance trans-2-octacosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76383 chebi_ph7_3 CHEBI:134526 biolink:ChemicalSubstance S-(long-chain fatty acyl)-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134526 CL:0000586 biolink:Cell germ cell The reproductive cell in multicellular organisms. go-plus.json http://purl.obolibrary.org/obo/CL_0000586 CL:0000588 biolink:Cell odontoclast A specialized osteoclast associated with the absorption and removal of cementum. go-plus.json http://purl.obolibrary.org/obo/CL_0000588 CHEBI:76386 biolink:ChemicalSubstance triacontanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76386 chebi_ph7_3 CHEBI:76387 biolink:ChemicalSubstance (3R,11Z)-3-hydroxyicosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76387 chebi_ph7_3 CHEBI:76384 biolink:ChemicalSubstance (R)-3-hydroxytriacontanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76384 chebi_ph7_3 CHEBI:76385 biolink:ChemicalSubstance trans-2-triacontenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76385 chebi_ph7_3 CHEBI:52371 biolink:ChemicalSubstance N-(2-hydroxytetracosanoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52371 chebi_ph7_3 CHEBI:52372 biolink:ChemicalSubstance N-(2-hydroxyhexacosanoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52372 chebi_ph7_3 CHEBI:76388 biolink:ChemicalSubstance (2E,11Z)-icosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76388 chebi_ph7_3 CHEBI:52373 biolink:ChemicalSubstance N-(2-hydroxytetracosanoyl)phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52373 chebi_ph7_3 CHEBI:76389 biolink:ChemicalSubstance (3R,13Z)-3-hydroxydocosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76389 chebi_ph7_3 CHEBI:52374 biolink:ChemicalSubstance N-(2-hydroxyhexacosanyl)-(4R)-phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52374 chebi_ph7_3 GO:0015407 biolink:MolecularActivity ABC-type monosaccharide transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported. EC:7.5.2.-|MetaCyc:3.6.3.17-RXN go-plus.json monosaccharide-transporting ATPase activity|monosaccharide-importing ATPase activity|ATP-dependent monosaccharide transmembrane transporter activity|ATPase-coupled monosaccharide transmembrane transporter activity|monosaccharide ABC transporter http://purl.obolibrary.org/obo/GO_0015407 GO:0015408 biolink:MolecularActivity ABC-type ferric iron transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in). MetaCyc:3.6.3.30-RXN|EC:7.2.2.7|RHEA:12332 go-plus.json ATPase-coupled ferric iron transmembrane transporter activity|ferric transporting ATPase activity|ferric ABC transporter|Fe3+-transporting ATPase activity|ABC-type Fe3+ transporter|ferric-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015408 GO:0015409 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015409 GO:0015403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015403 CHEBI:134532 biolink:ChemicalSubstance 3-(omega-methylthio)alkylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134532 CHEBI:134533 biolink:ChemicalSubstance 3-(2-methylthioethyl)malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134533 GO:0015404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015404 CL:0000593 biolink:Cell androgen secreting cell A steroid hormone secreting cell that secretes androgen. go-plus.json http://purl.obolibrary.org/obo/CL_0000593 GO:0015405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015405 CL:0000594 biolink:Cell skeletal muscle satellite cell An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. go-plus.json http://purl.obolibrary.org/obo/CL_0000594 CHEBI:134530 biolink:ChemicalSubstance 2-(omega-methylthio)alkylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134530 GO:0015406 biolink:MolecularActivity obsolete ABC-type uptake permease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ABC-type uptake permease activity http://purl.obolibrary.org/obo/GO_0015406 CL:0000595 biolink:Cell enucleate erythrocyte An erythrocyte lacking a nucleus. go-plus.json red blood cell|RBC http://purl.obolibrary.org/obo/CL_0000595 CHEBI:134531 biolink:ChemicalSubstance polyunsaturated dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134531 CL:0000596 biolink:Cell sexual spore A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. go-plus.json meiotically-derived spore http://purl.obolibrary.org/obo/CL_0000596 CHEBI:76393 biolink:ChemicalSubstance (2E,15Z)-tetracosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76393 chebi_ph7_3 CHEBI:134536 biolink:ChemicalSubstance 2-(2-methylthiopropyl)maleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134536 CHEBI:134537 biolink:ChemicalSubstance 3-(3-methylthio)propylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134537 GO:0015400 biolink:MolecularActivity low-affinity secondary active ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity ammonium transmembrane transporter activity|low affinity secondary active ammonium transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015400 CL:0000598 biolink:Cell pyramidal neuron Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. go-plus.json pyramidal cell|projection neuron|pyramidal neuron http://purl.obolibrary.org/obo/CL_0000598 GO:0015401 biolink:MolecularActivity urea:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in). go-plus.json urea active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015401 CHEBI:76391 biolink:ChemicalSubstance (2E,13Z)-docosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76391 chebi_ph7_3 CHEBI:134534 biolink:ChemicalSubstance 2-(omega-methylthio)alkylmaleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134534 CHEBI:134535 biolink:ChemicalSubstance 2-(2-methylthio)ethylmaleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134535 GO:0015402 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015402 CHEBI:76392 biolink:ChemicalSubstance (3R,15Z)-3-hydroxytetracosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76392 chebi_ph7_3 CL:0000599 biolink:Cell conidium An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/CL_0000599 CHEBI:52360 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_52360 NCBITaxon:1525212 biolink:OrganismalEntity Bathycoccaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1525212 CHEBI:52362 biolink:ChemicalSubstance ortho-fused heteroarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_52362 GO:1990156 biolink:CellularComponent DnaB-DnaG complex A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes. go-plus.json DnaB-DnaG primosome complex http://purl.obolibrary.org/obo/GO_1990156 GO:1990157 biolink:CellularComponent DnaA-DnaB-DnaC complex A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation. go-plus.json http://purl.obolibrary.org/obo/GO_1990157 GO:1990158 biolink:CellularComponent DnaB-DnaC-DnaT-PriA-PriB complex A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired. go-plus.json phi-X174-type preprimosome|DnaB-DnaC-DnaT-PriA-PriB preprimosome http://purl.obolibrary.org/obo/GO_1990158 GO:1990159 biolink:CellularComponent DnaB-DnaC-DnaT-PriA-PriC complex A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired. go-plus.json phi-X174-type preprimosome|DnaB-DnaC-DnaT-PriA-PriC preprimosome http://purl.obolibrary.org/obo/GO_1990159 GO:1990152 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990152 GO:1990153 biolink:BiologicalProcess maintenance of protein localization to heterochromatin A process in which a protein is maintained in a location in telomeric heterochromatin. go-plus.json maintenance of protein localisation to heterochromatin|maintenance of protein location in heterochromatin http://purl.obolibrary.org/obo/GO_1990153 GO:1990154 biolink:CellularComponent enzyme IIA-maltose transporter complex A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter. go-plus.json EIIA(Glc)-maltose transporter complex|maltose transporter inhibitor complex|EIIA(Glc)-MalFGK2 complex http://purl.obolibrary.org/obo/GO_1990154 GO:1990155 biolink:BiologicalProcess Dsc E3 ubiquitin ligase complex assembly The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane. go-plus.json Dsc complex assembly http://purl.obolibrary.org/obo/GO_1990155 CL:0000568 biolink:Cell amine precursor uptake and decarboxylation cell A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. go-plus.json APUD cell http://purl.obolibrary.org/obo/CL_0000568 CHEBI:27398 biolink:ChemicalSubstance imidazole-4-acetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27398 chebi_ph7_3 CL:0000569 biolink:Cell cardiac mesenchymal cell A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. go-plus.json http://purl.obolibrary.org/obo/CL_0000569 GO:1990150 biolink:CellularComponent VEGF-A complex A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase. go-plus.json vascular endothelial growth factor A complex http://purl.obolibrary.org/obo/GO_1990150 GO:1990151 biolink:BiologicalProcess protein localization to cell tip A process in which a protein is transported to, or maintained in, a location at the cell tip. go-plus.json protein localisation to cell tip http://purl.obolibrary.org/obo/GO_1990151 UBERON:0010740 biolink:AnatomicalEntity bone of appendage girdle complex A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). go-plus.json bone of extended limb/fin region|limb bone http://purl.obolibrary.org/obo/UBERON_0010740 UBERON:0010741 biolink:AnatomicalEntity bone of pectoral complex A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin. go-plus.json bone of forelimb or pectoral fin or pectoral girdle|wing bone|forelimb bone http://purl.obolibrary.org/obo/UBERON_0010741 CHEBI:27394 biolink:ChemicalSubstance D-erythro-3-methylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27394 CHEBI:134509 biolink:ChemicalSubstance 13,14-dihydro-15-keto-PGF1alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_134509 CL:0000561 biolink:Cell amacrine cell Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons. go-plus.json amacrine neuron http://purl.obolibrary.org/obo/CL_0000561 CL:0000562 biolink:Cell nucleate erythrocyte An erythrocyte having a nucleus. go-plus.json red blood cell|RBC http://purl.obolibrary.org/obo/CL_0000562 UBERON:0009758 biolink:AnatomicalEntity abdominal ganglion A ganglion that is part of a abdominal segment of trunk. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009758 CL:0000563 biolink:Cell endospore A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged. go-plus.json bacterial spore http://purl.obolibrary.org/obo/CL_0000563 CL:0000564 biolink:Cell neutrophilic promyelocyte A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. go-plus.json neutrophilic premyelocyte|neutrophilic progranulocyte http://purl.obolibrary.org/obo/CL_0000564 CL:0000566 biolink:Cell angioblastic mesenchymal cell A mesenchymal stem cell capable of developing into blood vessel endothelium. go-plus.json angioblast|chondroplast http://purl.obolibrary.org/obo/CL_0000566 CHEBI:134502 biolink:ChemicalSubstance phosphatidylethanolamine 40:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134502 UBERON:0009751 biolink:AnatomicalEntity cardiac mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures go-plus.json heart mesenchyme http://purl.obolibrary.org/obo/UBERON_0009751 CHEBI:52350 biolink:ChemicalSubstance 3-oxoicosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52350 UBERON:0009752 biolink:AnatomicalEntity pancreas mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas go-plus.json http://purl.obolibrary.org/obo/UBERON_0009752 CHEBI:52351 biolink:ChemicalSubstance 3-oxodocosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52351 CHEBI:52352 biolink:ChemicalSubstance 3-oxotetracosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52352 GO:1990167 biolink:BiologicalProcess protein K27-linked deubiquitination A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990167 GO:1990168 biolink:BiologicalProcess protein K33-linked deubiquitination A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990168 GO:1990169 biolink:BiologicalProcess stress response to copper ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus. go-plus.json response to copper ion stress|stress response to copper|response to copper toxicity http://purl.obolibrary.org/obo/GO_1990169 GO:1990163 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990163 GO:1990164 biolink:BiologicalProcess histone H2A phosphorylation The modification of histone H2A by the addition of a phosphate group. go-plus.json http://purl.obolibrary.org/obo/GO_1990164 CHEBI:52347 biolink:ChemicalSubstance 3-hydroxyicosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52347 GO:1990165 biolink:MolecularActivity single-strand break-containing DNA binding Binding to damaged DNA containing single-strand breaks (SSBs). go-plus.json single-strand break-containing damaged DNA binding|SSB-containing DNA binding http://purl.obolibrary.org/obo/GO_1990165 CHEBI:52348 biolink:ChemicalSubstance 3-hydroxydocosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52348 GO:1990166 biolink:BiologicalProcess protein localization to site of double-strand break Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred. go-plus.json protein localisation to site of double-strand break|protein localization to site of DSB|protein localization to double-strand break site http://purl.obolibrary.org/obo/GO_1990166 GO:1990160 biolink:CellularComponent DnaB-DnaC-Rep-PriC complex A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired. go-plus.json DnaB-DnaC-Rep-PriC preprimosome|phi-X174-type preprimosome http://purl.obolibrary.org/obo/GO_1990160 CL:0000579 biolink:Cell border follicle cell go-plus.json http://purl.obolibrary.org/obo/CL_0000579 GO:1990161 biolink:CellularComponent DnaB helicase complex A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair. go-plus.json DnaB hexamer http://purl.obolibrary.org/obo/GO_1990161 GO:1990162 biolink:MolecularActivity histone deacetylase activity (H3-K4 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990162 CL:0000570 biolink:Cell parafollicular cell A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine. go-plus.json parafollicular cell of thyroid gland|C cell of thyroid gland|C cell|thyroid parafollicular cell|clear cell of thyroid gland http://purl.obolibrary.org/obo/CL_0000570 UBERON:0009744 biolink:AnatomicalEntity lymph node medullary sinus The channels in the lymph node medulla that separate the medullary cords and are crossed by a reticulum of cells and fibers and bounded by littoral cells; lymph flows through the medullary sinus from the cortical sinuses and into the efferent lymphatic vessels go-plus.json medullary sinus|lymph node medullary sinusoid http://purl.obolibrary.org/obo/UBERON_0009744 CL:0000571 biolink:Cell leucophore A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. go-plus.json http://purl.obolibrary.org/obo/CL_0000571 UBERON:0009745 biolink:AnatomicalEntity lymph node medullary cord The dense rope-like structures of lymphatic tissue located between the medullary sinuses in the medulla of a lymph node go-plus.json medullary cord http://purl.obolibrary.org/obo/UBERON_0009745 UBERON:0010720 biolink:AnatomicalEntity hindlimb zeugopod skeleton Subdivision of skeleton consisting of all skeletal elements in an hindlimb zeugopod region. Typically consists of the tibia and the fibula. go-plus.json hind epipodium|skeleton cruris|posterior zeugopodium|hindlimb zygopod skeleton|posterior zeugopodium skeleton|crus skeleton|hindlimb epipodium|crural skeleton|mesomere 2 of pelvic appendage http://purl.obolibrary.org/obo/UBERON_0010720 CL:0000573 biolink:Cell retinal cone cell One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. go-plus.json http://purl.obolibrary.org/obo/CL_0000573 CL:0000574 biolink:Cell erythrophore A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. go-plus.json http://purl.obolibrary.org/obo/CL_0000574 CL:0000575 biolink:Cell corneal epithelial cell An epithelial cell of the cornea. go-plus.json epithelial cell of cornea http://purl.obolibrary.org/obo/CL_0000575 UBERON:0009749 biolink:AnatomicalEntity limb mesenchyme The primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells. go-plus.json limb mesoderm http://purl.obolibrary.org/obo/UBERON_0009749 CL:0000576 biolink:Cell monocyte Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. go-plus.json http://purl.obolibrary.org/obo/CL_0000576 CHEBI:52342 biolink:ChemicalSubstance ethyl formate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52342 chebi_ph7_3 CHEBI:52343 biolink:ChemicalSubstance formate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_52343 UBERON:0010728 biolink:AnatomicalEntity sphenoid lesser wing pre-cartilage condensation A orbitosphenoid endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010728 CHEBI:52340 biolink:ChemicalSubstance tricyclic triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52340 GO:1990178 biolink:CellularComponent HU-DNA complex A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure. go-plus.json HU complex http://purl.obolibrary.org/obo/GO_1990178 GO:1990179 biolink:BiologicalProcess protein localization to actomyosin contractile ring A process in which a protein is transported to, or maintained at, the actomyosin contractile ring. go-plus.json protein localisation to actomyosin contractile ring http://purl.obolibrary.org/obo/GO_1990179 GO:1990174 biolink:MolecularActivity phosphodiesterase decapping endonuclease activity Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA. go-plus.json G(5')pppN pyrophosphatase activity http://purl.obolibrary.org/obo/GO_1990174 CHEBI:27379 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_27379 GO:1990175 biolink:MolecularActivity EH domain binding Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R. go-plus.json http://purl.obolibrary.org/obo/GO_1990175 GO:1990176 biolink:CellularComponent MalFGK2 complex Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG. go-plus.json MalFGK(2) complex|MalF-MalG-MalK-MalK complex|MalF-MalG-MalK(2) complex|maltose transport MalFGK2 complex|maltose transport complex, core subunit http://purl.obolibrary.org/obo/GO_1990176 GO:1990177 biolink:CellularComponent IHF-DNA complex A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid. go-plus.json IHFa-IHFb-DNA complex|IHF complex http://purl.obolibrary.org/obo/GO_1990177 CL:0000545 biolink:Cell T-helper 1 cell A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. go-plus.json Th1 cell|T helper cells type 1|Th1 T-cell|Th1 T-lymphocyte|Th1 CD4+ T cell|Th1 T cell|Th1 T lymphocyte|helper T cell type 1|T(H)-1 cell http://purl.obolibrary.org/obo/CL_0000545 GO:1990170 biolink:BiologicalProcess stress response to cadmium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus. go-plus.json response to cadmium ion stress|response to cadmium toxicity|stress response to cadmium http://purl.obolibrary.org/obo/GO_1990170 CL:0000546 biolink:Cell T-helper 2 cell A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. go-plus.json T(H)-2 cell|Th2 cell|T helper cells type 2|Th2 T-cell|Th2 T-lymphocyte|Th2 T cell|Th2 T lymphocyte|helper T cell type 2 http://purl.obolibrary.org/obo/CL_0000546 GO:1990171 biolink:BiologicalProcess SCF complex disassembly in response to cadmium stress The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress. go-plus.json http://purl.obolibrary.org/obo/GO_1990171 CHEBI:27376 biolink:ChemicalSubstance methanesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27376 GO:1990172 biolink:BiologicalProcess G protein-coupled receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor. go-plus.json G-protein coupled receptor catabolic process http://purl.obolibrary.org/obo/GO_1990172 CL:0000547 biolink:Cell proerythroblast An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. go-plus.json rubriblast|pronormoblast http://purl.obolibrary.org/obo/CL_0000547 GO:1990173 biolink:BiologicalProcess protein localization to nucleoplasm A process in which a protein is transported to, or maintained in, a location within the nucleoplasm. go-plus.json nucleolus to nucleoplasm transport|protein localisation to nucleoplasm http://purl.obolibrary.org/obo/GO_1990173 CL:0000548 biolink:Cell animal cell go-plus.json http://purl.obolibrary.org/obo/CL_0000548 CHEBI:27378 biolink:ChemicalSubstance (2S,3R)-aldopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27378 chebi_ph7_3 CL:0000549 biolink:Cell basophilic erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. go-plus.json early normoblast|early erythroblast|basophilic normoblast|prorubricyte http://purl.obolibrary.org/obo/CL_0000549 CHEBI:27372 biolink:ChemicalSubstance 1D-chiro-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27372 chebi_ph7_3 CHEBI:27374 biolink:ChemicalSubstance 1L-chiro-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27374 chebi_ph7_3 UBERON:0010711 biolink:AnatomicalEntity pelvic fin skeleton Paired fin skeleton located in the abdominal position that consists of supporting endochondral radialsB and dermal fin rays or lepidotrichia. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010711 UBERON:0010712 biolink:AnatomicalEntity limb skeleton subdivision Skeletal subdivision that is a segment of the limb skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010712 CHEBI:27380 biolink:ChemicalSubstance (1->6)-beta-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27380 chebi_ph7_3 UBERON:0010710 biolink:AnatomicalEntity pectoral fin skeleton Paired fin skeleton that consists of the supporting endochondral proximal and distal radials and the dermal fins rays or lepidotrichia. The pectoral fin skeleton is located in the thoracic region of the body and articulates with the scapula and coracoid. go-plus.json forefin skeleton http://purl.obolibrary.org/obo/UBERON_0010710 CL:0000540 biolink:Cell neuron The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. go-plus.json nerve cell http://purl.obolibrary.org/obo/CL_0000540 CHEBI:27381 biolink:ChemicalSubstance 2,2',3-trihydroxydiphenyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_27381 CL:0000541 biolink:Cell melanoblast A cell that originates from the neural crest and differentiates into a pigment cell. go-plus.json http://purl.obolibrary.org/obo/CL_0000541 CL:0000542 biolink:Cell lymphocyte A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. go-plus.json http://purl.obolibrary.org/obo/CL_0000542 UBERON:0010713 biolink:AnatomicalEntity paired fin skeleton The collection of all skeletal elements in a single paired fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010713 UBERON:0010719 biolink:AnatomicalEntity girdle skeleton The subdivision of the skeleton of either the pectoral or pelvic girdle. go-plus.json skeleton of girdle http://purl.obolibrary.org/obo/UBERON_0010719 CHEBI:52333 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52333 chebi_ph7_3 CHEBI:52330 biolink:ChemicalSubstance glycerophosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_52330 GO:1990189 biolink:MolecularActivity peptide-serine-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide. go-plus.json http://purl.obolibrary.org/obo/GO_1990189 CHEBI:52328 biolink:ChemicalSubstance 3-oxodocosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52328 CHEBI:52329 biolink:ChemicalSubstance 3-oxotetracosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52329 CHEBI:52324 biolink:ChemicalSubstance 3-hydroxyicosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52324 GO:1990185 biolink:BiologicalProcess regulation of lymphatic vascular permeability Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid. go-plus.json http://purl.obolibrary.org/obo/GO_1990185 GO:1990186 biolink:BiologicalProcess regulation of lymphatic vessel size Any process that modulates the size of lymphatic vessels. go-plus.json regulation of collecting lymphatic vessel size http://purl.obolibrary.org/obo/GO_1990186 CHEBI:52325 biolink:ChemicalSubstance 3-hydroxydocosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52325 GO:1990187 biolink:BiologicalProcess obsolete protein localization to mRNA OBSOLETE. A process in which a protein is transported to, or maintained at mRNA. go-plus.json protein localization to mRNA http://purl.obolibrary.org/obo/GO_1990187 GO:1990188 biolink:MolecularActivity euchromatin binding Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_1990188 CHEBI:52327 biolink:ChemicalSubstance 3-oxoicosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52327 CL:0000556 biolink:Cell megakaryocyte A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. go-plus.json megalokaryocyte|megacaryocyte|megalocaryocyte http://purl.obolibrary.org/obo/CL_0000556 GO:1990181 biolink:BiologicalProcess acetyl-CoA biosynthetic process from pantothenate The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA. go-plus.json acetyl-CoA anabolism from pantothenate|acetyl-CoA synthesis from pantothenate|acetyl-CoA formation from pantothenate http://purl.obolibrary.org/obo/GO_1990181 CHEBI:27386 biolink:ChemicalSubstance cinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27386 GO:1990182 biolink:BiologicalProcess exosomal secretion The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. go-plus.json multi-vesicular body fusion with plasma membrane|exosomal secretory pathway|secretion of exosome|extracellular vesicular exosome secretion|exosomal protein secretion http://purl.obolibrary.org/obo/GO_1990182 CL:0000557 biolink:Cell granulocyte monocyte progenitor cell A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. go-plus.json granulocyte-macrophage progenitor|granulocyte/monocyte precursor|GMP|colony forming unit granulocyte macrophage|CFU-C , Colony forming unit in culture|CFU-GM|granulocyte/monocyte progenitor http://purl.obolibrary.org/obo/CL_0000557 CL:0000558 biolink:Cell reticulocyte An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. go-plus.json http://purl.obolibrary.org/obo/CL_0000558 GO:1990183 biolink:BiologicalProcess lymphatic vascular process in circulatory system A circulatory process that occurs at the level of the lymphatic vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_1990183 GO:1990184 biolink:CellularComponent amino acid transport complex A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990184 CL:0000559 biolink:Cell promonocyte A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. go-plus.json http://purl.obolibrary.org/obo/CL_0000559 CHEBI:27389 biolink:ChemicalSubstance 3-aminoisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27389 CHEBI:27384 biolink:ChemicalSubstance 3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27384 CHEBI:27385 biolink:ChemicalSubstance tetrachloromethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_27385 chebi_ph7_3 GO:1990180 biolink:BiologicalProcess mitochondrial tRNA 3'-end processing The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion. go-plus.json tRNA 3' processing in mitochondrion|tRNA 3' processing in mitochondria|tRNA 3'-end processing in mitochondria http://purl.obolibrary.org/obo/GO_1990180 UBERON:0009722 biolink:AnatomicalEntity entire pharyngeal arch endoderm go-plus.json pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0009722 UBERON:0010700 biolink:AnatomicalEntity phalanx pre-cartilage condensation go-plus.json http://purl.obolibrary.org/obo/UBERON_0010700 UBERON:0010701 biolink:AnatomicalEntity phalanx cartilage element go-plus.json phalanx cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010701 CHEBI:27390 biolink:ChemicalSubstance omega-aminoaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_27390 CL:0000550 biolink:Cell polychromatophilic erythroblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. go-plus.json polychromatophilic normoblast|polychromatic erythroblast|intermediate normoblast|intermediate erythroblast|rubricyte|polychromatic normoblast http://purl.obolibrary.org/obo/CL_0000550 CHEBI:27391 biolink:ChemicalSubstance 1-pyrroline-3-hydroxy-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27391 CHEBI:27392 biolink:ChemicalSubstance UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27392 CL:0000552 biolink:Cell orthochromatic erythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. go-plus.json acidophilic erythroblast|late erythoblast|eosinophilic erythroblast|orthochromatic normoblast|pyknotic eto enrythroblast http://purl.obolibrary.org/obo/CL_0000552 CL:0000553 biolink:Cell megakaryocyte progenitor cell The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). go-plus.json promegakaryocyte|CFU-Meg|colony-forming unit-megakaryocyte|MkP|megacaryocyte progenitor cell|promegacaryocyte|megakaryocytic progenitor cell|Meg-CFC|megacaryoblast|megakaryoblast http://purl.obolibrary.org/obo/CL_0000553 UBERON:0010702 biolink:AnatomicalEntity digit mesenchyme Mesenchyme of the digit region. go-plus.json digital ray http://purl.obolibrary.org/obo/UBERON_0010702 UBERON:0010703 biolink:AnatomicalEntity forelimb zeugopod skeleton The collection of all skeletal elements in an forelimb zeugopod region. go-plus.json fore epipodium|antebrachial skeleton|mesomere 2 of pectoral appendage|forearm skeleton|wing zeugopod skeleton|skeleton of forearm|anterior zeugopodium skeleton|antebrachium skeleton|forelimb epipodium|anterior zeugopodium|forelimb epipodium skeleton|radius and ulna|fore epipodium skeleton http://purl.obolibrary.org/obo/UBERON_0010703 UBERON:0010708 biolink:AnatomicalEntity pectoral complex Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle. go-plus.json pectoral appendage/girdle complex|pectoral girdle plus anterior limb or fin|pectoral girdle plus pectoral limb or fin|upper limb|upper limb and pectoral girdle|upper limb and shoulder http://purl.obolibrary.org/obo/UBERON_0010708 CHEBI:52320 biolink:ChemicalSubstance ergosteryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_52320 chebi_ph7_3 UBERON:0010709 biolink:AnatomicalEntity pelvic complex Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle. go-plus.json pelvic girdle plus pelvic limb or fin|pelvic appendage/girdle complex|lower limb|pelvic girdle plus posterior limb or fin|lower limb and pelvis|lower limb and pelvic girdle http://purl.obolibrary.org/obo/UBERON_0010709 CHEBI:52322 biolink:ChemicalSubstance zymosterol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_52322 chebi_ph7_3 UBERON:0010707 biolink:AnatomicalEntity appendage girdle complex An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). go-plus.json limb|girdle plus limb or fin|appendage/girdle complex|appendage-girdle complex|appendage complex http://purl.obolibrary.org/obo/UBERON_0010707 CHEBI:52323 biolink:ChemicalSubstance 1,2-dioleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52323 chebi_ph7_3 GO:1990112 biolink:CellularComponent RQC complex A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. go-plus.json ribosome quality control complex|ribosome-bound quality control complex http://purl.obolibrary.org/obo/GO_1990112 GO:1990113 biolink:BiologicalProcess RNA polymerase I assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex. go-plus.json RNA Polymerase I complex assembly|DNA-directed RNA polymerase I complex assembly http://purl.obolibrary.org/obo/GO_1990113 GO:1990114 biolink:BiologicalProcess RNA polymerase II core complex assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex. go-plus.json DNA-directed RNA polymerase II, core complex assembly|RNA Polymerase II assembly http://purl.obolibrary.org/obo/GO_1990114 GO:1990115 biolink:BiologicalProcess RNA polymerase III assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex. go-plus.json RNA Polymerase III complex assembly|DNA-directed RNA polymerase III complex assembly http://purl.obolibrary.org/obo/GO_1990115 GO:1990110 biolink:BiologicalProcess callus formation The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate. go-plus.json http://purl.obolibrary.org/obo/GO_1990110 GO:1990111 biolink:CellularComponent spermatoproteasome complex A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity. go-plus.json http://purl.obolibrary.org/obo/GO_1990111 CHEBI:66961 biolink:ChemicalSubstance cannabinerolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66961 chebi_ph7_3 CHEBI:66962 biolink:ChemicalSubstance cannabigerolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66962 chebi_ph7_3 CHEBI:66963 biolink:ChemicalSubstance Delta(9)-tetrahydrocannabinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66963 chebi_ph7_3 CHEBI:66964 biolink:ChemicalSubstance Delta(9)-tetrahydrocannabinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_66964 chebi_ph7_3 CHEBI:66960 biolink:ChemicalSubstance olivetol go-plus.json http://purl.obolibrary.org/obo/CHEBI_66960 chebi_ph7_3 GO:0015498 biolink:MolecularActivity pantothenate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015498 GO:0015499 biolink:MolecularActivity formate transmembrane transporter activity Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. RHEA:29679 go-plus.json formate uptake transmembrane transporter activity|formate uptake permease activity http://purl.obolibrary.org/obo/GO_0015499 GO:0015494 biolink:MolecularActivity aromatic amino acid:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in). go-plus.json aromatic amino acid:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015494 GO:0015495 biolink:MolecularActivity gamma-aminobutyric acid:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in). Reactome:R-HSA-428625 go-plus.json GABA:hydrogen symporter activity|4-aminobutyrate:proton symporter activity|GABA:proton symporter activity|gamma-aminobutyric acid permease activity|4-aminobutanoate:hydrogen symporter activity|4-aminobutanoate:proton symporter activity|gamma-aminobutyric acid:hydrogen symporter activity|4-aminobutyrate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015495 GO:0015496 biolink:MolecularActivity putrescine:ornithine antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out). go-plus.json putrescine:hydrogen symporter activity|putrescine-ornithine antiporter activity|putrescine/ornithine antiporter activity http://purl.obolibrary.org/obo/GO_0015496 GO:0015497 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015497 GO:1990116 biolink:BiologicalProcess ribosome-associated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein. go-plus.json ribosome-associated ubiquitin-dependent protein degradation|ribosome-associated ubiquitin-dependent protein breakdown|ribosome-associated degradation|ribosome-associated ubiquitin-dependent protein catabolism|RAD http://purl.obolibrary.org/obo/GO_1990116 GO:0015490 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015490 GO:0015491 biolink:MolecularActivity cation:cation antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015491 GO:1990117 biolink:BiologicalProcess B cell receptor apoptotic signaling pathway An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell. go-plus.json B cell receptor extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway via BCR|extrinsic apoptotic signaling pathway via B cell antigen receptor http://purl.obolibrary.org/obo/GO_1990117 GO:1990118 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990118 GO:0015492 biolink:MolecularActivity phenylalanine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in). go-plus.json phenylalanine:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015492 GO:0015493 biolink:MolecularActivity lysine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in). go-plus.json lysine:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015493 GO:1990119 biolink:MolecularActivity RNA helicase inhibitor activity Binds to and stops, prevents or reduces the activity of an RNA helicase. go-plus.json ATP-dependent RNA helicase inhibitor activity http://purl.obolibrary.org/obo/GO_1990119 GO:1990123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990123 GO:1990124 biolink:CellularComponent messenger ribonucleoprotein complex A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules. go-plus.json messenger ribonucleoprotein particle|mRNP|mRNP complex|mRNA-protein complex http://purl.obolibrary.org/obo/GO_1990124 GO:1990125 biolink:CellularComponent DiaA complex A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation. go-plus.json DiaA homotetramer http://purl.obolibrary.org/obo/GO_1990125 GO:1990126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990126 GO:1990120 biolink:BiologicalProcess messenger ribonucleoprotein complex assembly The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex. go-plus.json messenger ribonucleoprotein assembly|mRNP assembly|mRNP complex assembly|mRNA-protein complex assembly http://purl.obolibrary.org/obo/GO_1990120 GO:1990121 biolink:CellularComponent H-NS complex A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA. go-plus.json DNA-binding protein H-NS complex|histone-like protein H-NS complex http://purl.obolibrary.org/obo/GO_1990121 GO:1990122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990122 GO:1990127 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered. go-plus.json http://purl.obolibrary.org/obo/GO_1990127 GO:1990128 biolink:CellularComponent obsolete pre-primosome complex involved in replication initiation OBSOLETE. A protein-DNA complex involved in replication initiation at the origin of replication. go-plus.json pre-primosome complex involved in replication initiation http://purl.obolibrary.org/obo/GO_1990128 GO:1990129 biolink:CellularComponent obsolete pre-primosome complex involved in replication restart OBSOLETE. A protein-DNA complex involved in replication restart after a stalled replication fork has been repaired. go-plus.json pre-primosome complex involved in replication restart http://purl.obolibrary.org/obo/GO_1990129 GO:1990134 biolink:BiologicalProcess epithelial cell apoptotic process involved in palatal shelf morphogenesis An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf. go-plus.json http://purl.obolibrary.org/obo/GO_1990134 CHEBI:76306 biolink:ChemicalSubstance (+)-menthol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76306 chebi_ph7_3 GO:1990135 biolink:MolecularActivity flavonoid sulfotransferase activity Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative. go-plus.json http://purl.obolibrary.org/obo/GO_1990135 CHEBI:76307 biolink:ChemicalSubstance omega-hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76307 chebi_ph7_3 CHEBI:76304 biolink:ChemicalSubstance 22-hydroxydocosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76304 chebi_ph7_3 GO:1990136 biolink:MolecularActivity linoleate 9S-lipoxygenase activity Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate. EC:1.13.11.58|RHEA:30291 go-plus.json 9S-lipoxygenase activity|9-lipoxygenase activity|linoleate 9-lipoxygenase activity|linoleate:oxygen 9S-oxidoreductase activity http://purl.obolibrary.org/obo/GO_1990136 CHEBI:76305 biolink:ChemicalSubstance 26-hydroxyhexacosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76305 chebi_ph7_3 GO:1990137 biolink:MolecularActivity plant seed peroxidase activity Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH. EC:1.11.2.3|MetaCyc:RXN-11819 go-plus.json peroxygenase activity http://purl.obolibrary.org/obo/GO_1990137 GO:1990130 biolink:CellularComponent GATOR1 complex A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins. go-plus.json IML1 complex|SEACIT complex http://purl.obolibrary.org/obo/GO_1990130 PO:0004703 biolink:OntologyClass carpel primordium A phyllome primordium (PO:0025128) that develops from a carpel anlagen (PO:0006005) and is committed to the development of a carpel (PO:0009030). go-plus.json 心皮原基(可視的） (Japanese, exact)|portion of carpel primordium tissue (exact)|primordio de carpelo (Spanish, exact)|carpel primordia (exact, plural) http://purl.obolibrary.org/obo/PO_0004703 GO:1990131 biolink:CellularComponent Gtr1-Gtr2 GTPase complex A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990131 PO:0004704 biolink:OntologyClass sepal primordium A phyllome primordium (PO:0025128) that develops from a sepal anlagen (PO:0025485) and is committed to the development of a sepal (PO:0009031). go-plus.json portion of sepal primordium tissue (exact)|がく片原基（可視的） (Japanese, exact)|sepal primordia (exact, plural)|primordio de sépalo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0004704 GO:1990132 biolink:BiologicalProcess obsolete release of misfolded protein from chaperone OBSOLETE. The release of misfolded proteins that are being held by the chaperone heat shock protein (Hsp) and targeting them for destruction by the Ub-proteasome machinery. go-plus.json release of misfolded protein from chaperone http://purl.obolibrary.org/obo/GO_1990132 CHEBI:76308 biolink:ChemicalSubstance tetradecanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76308 GO:1990133 biolink:CellularComponent molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved. go-plus.json http://purl.obolibrary.org/obo/GO_1990133 CHEBI:76309 biolink:ChemicalSubstance omega-oxo fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76309 chebi_ph7_3 PO:0004705 biolink:OntologyClass stamen primordium A phyllome primordium (PO:0025128) that develops from a stamen anlagen (PO:0025486) and is committed to the development of a stamen (PO:0009029). go-plus.json 雄蕊原基（可視的） (Japanese, exact)|primordio de estambre (Spanish, exact)|stamen primordia (exact, plural)|portion of stamen primordium tissue (exact) http://purl.obolibrary.org/obo/PO_0004705 CHEBI:66980 biolink:ChemicalSubstance nootropic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_66980 PO:0004709 biolink:OntologyClass axillary bud A bud (PO:0000055) that develops from an axillary bud meristem (PO:0000232). go-plus.json 腋芽 (Japanese, exact)|yema axilar (Spanish, exact) http://purl.obolibrary.org/obo/PO_0004709 CHEBI:66981 biolink:ChemicalSubstance ophthalmology drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_66981 CHEBI:66982 biolink:ChemicalSubstance mycophenolic acid O-acyl-glucuronide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66982 chebi_ph7_3 CHEBI:66987 biolink:ChemicalSubstance radiation protective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_66987 GO:0015476 biolink:MolecularActivity hemaglutinin autotransporter activity Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0015476 GO:0015477 biolink:MolecularActivity obsolete receptor porin activity OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane. go-plus.json receptor porin activity http://purl.obolibrary.org/obo/GO_0015477 GO:0015478 biolink:MolecularActivity oligosaccharide transporting porin activity Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. go-plus.json raffinose porin http://purl.obolibrary.org/obo/GO_0015478 GO:0015479 biolink:MolecularActivity obsolete outer membrane exporter porin OBSOLETE. (Was not defined before being made obsolete). go-plus.json outer membrane exporter porin http://purl.obolibrary.org/obo/GO_0015479 GO:0015472 biolink:MolecularActivity obsolete fimbrium-specific chaperone activity OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function. go-plus.json fimbrium-specific chaperone activity http://purl.obolibrary.org/obo/GO_0015472 GO:0015473 biolink:MolecularActivity fimbrial usher porin activity A porin that acts in the assembly of fimbria together with fimbrial chaperone. go-plus.json http://purl.obolibrary.org/obo/GO_0015473 GO:0015474 biolink:MolecularActivity autotransporter activity Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0015474 GO:0015475 biolink:MolecularActivity adhesin autotransporter activity Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0015475 GO:1990138 biolink:BiologicalProcess neuron projection extension Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. go-plus.json neuron process extension|neuron protrusion extension|neuronal cell projection extension|neurite extension http://purl.obolibrary.org/obo/GO_1990138 GO:1990139 biolink:BiologicalProcess protein localization to nuclear periphery A process in which a protein is transported to, or maintained in, a location within the nuclear periphery. go-plus.json http://purl.obolibrary.org/obo/GO_1990139 GO:0015470 biolink:MolecularActivity obsolete bacteriocin activity OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor. go-plus.json bacteriocin activity http://purl.obolibrary.org/obo/GO_0015470 CHEBI:76301 biolink:ChemicalSubstance inositol phosphate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76301 GO:0015471 biolink:MolecularActivity nucleoside-specific channel forming porin activity Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0015471 GO:1990145 biolink:BiologicalProcess maintenance of translational fidelity Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template. go-plus.json http://purl.obolibrary.org/obo/GO_1990145 CHEBI:76317 biolink:ChemicalSubstance octanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76317 chebi_ph7_3 GO:1990146 biolink:BiologicalProcess protein localization to rhabdomere A process in which a protein is transported to, or maintained in, a location within a rhabdomere. go-plus.json http://purl.obolibrary.org/obo/GO_1990146 CHEBI:76318 biolink:ChemicalSubstance 22-oxodocosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76318 CHEBI:76315 biolink:ChemicalSubstance dodecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76315 chebi_ph7_3 GO:1990147 biolink:MolecularActivity talin binding Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. go-plus.json http://purl.obolibrary.org/obo/GO_1990147 CHEBI:76316 biolink:ChemicalSubstance decanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76316 chebi_ph7_3 GO:1990148 biolink:CellularComponent glutamate dehydrogenase complex A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies. go-plus.json glutamic acid dehydrogenase complex|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) complex|L-glutamic acid dehydrogenase complex|NAD(P)H-dependent glutamate dehydrogenase complex|glutamic dehydrogenase complex|glutamate dehydrogenase (NADP+) complex|NAD(P)-glutamate dehydrogenase complex|L-glutamate:NADP+ oxidoreductase (deaminating) complex|L-glutamate dehydrogenase complex http://purl.obolibrary.org/obo/GO_1990148 GO:1990141 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990141 GO:1990142 biolink:BiologicalProcess envenomation resulting in hemolysis in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with hemolysis in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_1990142 GO:1990143 biolink:CellularComponent CoA-synthesizing protein complex A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway. go-plus.json CoA-SPC|coenzyme A-synthesizing protein complex http://purl.obolibrary.org/obo/GO_1990143 CHEBI:76319 biolink:ChemicalSubstance docosanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76319 GO:1990144 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to hypoxia A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered. go-plus.json http://purl.obolibrary.org/obo/GO_1990144 GO:1990140 biolink:CellularComponent MPT synthase complex A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved. go-plus.json molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex http://purl.obolibrary.org/obo/GO_1990140 CHEBI:66993 biolink:ChemicalSubstance tocolytic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_66993 GO:0015487 biolink:MolecularActivity melibiose:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in). go-plus.json melibiose:monovalent cation symporter activity|melibiose permease activity http://purl.obolibrary.org/obo/GO_0015487 CHEBI:66998 biolink:ChemicalSubstance histidinate derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_66998 GO:0015488 biolink:MolecularActivity glucuronide:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in). go-plus.json glucuronoside permease activity|glucuronide:monovalent cation symporter activity http://purl.obolibrary.org/obo/GO_0015488 GO:0015489 biolink:MolecularActivity putrescine transmembrane transporter activity Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. go-plus.json http://purl.obolibrary.org/obo/GO_0015489 GO:0015483 biolink:MolecularActivity long-chain fatty acid transporting porin activity Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. TC:1.B.9.1.1 go-plus.json http://purl.obolibrary.org/obo/GO_0015483 GO:0015484 biolink:MolecularActivity obsolete hemolysin activity OBSOLETE. Any substance that causes the lysis of red blood cells. go-plus.json hemolysin activity http://purl.obolibrary.org/obo/GO_0015484 GO:0015485 biolink:MolecularActivity cholesterol binding Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0015485 GO:0015486 biolink:MolecularActivity glycoside-pentoside-hexuronide:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+. go-plus.json http://purl.obolibrary.org/obo/GO_0015486 GO:1990149 biolink:BiologicalProcess obsolete COPI vesicle coating OBSOLETE. The addition of COPI proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat. go-plus.json COPI vesicle coating http://purl.obolibrary.org/obo/GO_1990149 GO:0015480 biolink:MolecularActivity obsolete secretin (sensu Bacteria) OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm). go-plus.json secretin (sensu Bacteria) http://purl.obolibrary.org/obo/GO_0015480 CHEBI:76314 biolink:ChemicalSubstance trans-2-nonenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76314 CHEBI:76311 biolink:ChemicalSubstance 26-oxohexacosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76311 chebi_ph7_3 GO:0015481 biolink:MolecularActivity maltose transporting porin activity Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. Wikipedia:Maltoporin go-plus.json maltoporin http://purl.obolibrary.org/obo/GO_0015481 GO:0015482 biolink:MolecularActivity obsolete voltage-gated anion channel porin activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json voltage-dependent anion channel porin activity|voltage-gated anion channel porin activity http://purl.obolibrary.org/obo/GO_0015482 CHEBI:76312 biolink:ChemicalSubstance hexacosanedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76312 chebi_ph7_3 CHEBI:76328 biolink:ChemicalSubstance omega-oxo fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76328 CHEBI:76327 biolink:ChemicalSubstance adipoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76327 chebi_ph7_3 GO:0015458 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015458 GO:0015459 biolink:MolecularActivity potassium channel regulator activity Binds to and modulates the activity of a potassium channel. go-plus.json potassium channel gating activity http://purl.obolibrary.org/obo/GO_0015459 GO:0015454 biolink:MolecularActivity light-driven active transmembrane transporter activity Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. TC:3.E go-plus.json light-driven pumps|Light absorption-driven transporters http://purl.obolibrary.org/obo/GO_0015454 GO:0015455 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015455 GO:0015456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015456 GO:0015457 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015457 GO:0015450 biolink:MolecularActivity protein-transporting ATPase activity Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Reactome:R-HSA-1222523 go-plus.json P-P-bond-hydrolysis-driven protein transmembrane transporter activity|protein translocase activity http://purl.obolibrary.org/obo/GO_0015450 GO:0015451 biolink:MolecularActivity decarboxylation-driven active transmembrane transporter activity Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. TC:3.B|EC:7.2.4.5|EC:7.2.4.4|EC:7.2.4.3|EC:7.2.4.2|EC:7.2.4.1 go-plus.json decarboxylation-driven transporter http://purl.obolibrary.org/obo/GO_0015451 GO:0015452 biolink:MolecularActivity methyl transfer-driven active transmembrane transporter activity Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. TC:3.C go-plus.json Methyltransfer-driven transporters http://purl.obolibrary.org/obo/GO_0015452 GO:0015453 biolink:MolecularActivity oxidoreduction-driven active transmembrane transporter activity Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. TC:3.D go-plus.json oxidoreduction-driven transporter http://purl.obolibrary.org/obo/GO_0015453 CHEBI:76325 biolink:ChemicalSubstance 26-hydroxyhexacosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76325 CHEBI:76322 biolink:ChemicalSubstance 22-hydroxydocosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76322 CHEBI:134582 biolink:ChemicalSubstance (4S)-4,16-dihydroxyretinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134582 CHEBI:76339 biolink:ChemicalSubstance dodecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76339 NCBITaxon:39700 biolink:OrganismalEntity Trypanozoon go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_39700 GO:0015469 biolink:MolecularActivity obsolete channel-forming toxin activity OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell. go-plus.json channel-forming toxin activity http://purl.obolibrary.org/obo/GO_0015469 GO:0015465 biolink:MolecularActivity obsolete lysin activity OBSOLETE. An agent that can lyse cells. go-plus.json lysin activity http://purl.obolibrary.org/obo/GO_0015465 GO:0015466 biolink:MolecularActivity obsolete autolysin activity OBSOLETE. An agent that can lyse the cell in which it is synthesized. go-plus.json autolysin activity http://purl.obolibrary.org/obo/GO_0015466 GO:0015467 biolink:MolecularActivity G-protein activated inward rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. Reactome:R-HSA-1013020 go-plus.json G protein enhanced inward rectifier potassium channel activity|G-protein-enhanced inward rectifier potassium channel activity|G-protein-activated inward rectifier potassium channel activity|G protein activated inward rectifier potassium channel activity|G-protein enhanced inward rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_0015467 GO:0015468 biolink:MolecularActivity obsolete colicin OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it. go-plus.json colicin http://purl.obolibrary.org/obo/GO_0015468 GO:0015461 biolink:MolecularActivity obsolete endosomal oligosaccharide transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json endosomal oligosaccharide transporter http://purl.obolibrary.org/obo/GO_0015461 GO:0015462 biolink:MolecularActivity ABC-type protein transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in). EC:7.4.2.5 go-plus.json ATPase-coupled protein transmembrane transporter activity|pilin/fimbrilin exporter activity|protein-transmembrane transporting ATPase activity|protein ABC transporter|ABC-type protein transmembrane transporter activity|protein-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015462 CHEBI:76332 biolink:ChemicalSubstance 26-oxohexacosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76332 GO:0015463 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015463 GO:0015464 biolink:MolecularActivity acetylcholine receptor activity Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0015464 CHEBI:76330 biolink:ChemicalSubstance trans-2-octenedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76330 chebi_ph7_3 CHEBI:76335 biolink:ChemicalSubstance 3-oxooctanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76335 chebi_ph7_3 CHEBI:76333 biolink:ChemicalSubstance (S)-3-hydroxyoctanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76333 chebi_ph7_3 CHEBI:76334 biolink:ChemicalSubstance hexacosanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76334 GO:0015460 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015460 CHEBI:76348 biolink:ChemicalSubstance (S)-3-hydroxydecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76348 chebi_ph7_3 CHEBI:76349 biolink:ChemicalSubstance 3-oxodecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76349 chebi_ph7_3 GO:0015436 biolink:MolecularActivity ABC-type capsular-polysaccharide transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out). MetaCyc:3.6.3.38-RXN|EC:7.6.2.12 go-plus.json ATP phosphohydrolase (capsular-polysaccharide-exporting)|ATP-dependent capsular-polysaccharide transporter activity|ATPase-coupled capsular-polysaccharide transporter activity|capsular-polysaccharide-transporting ATPase activity|capsular-polysaccharide ABC transporter http://purl.obolibrary.org/obo/GO_0015436 GO:0015437 biolink:MolecularActivity lipopolysaccharide floppase activity Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json ATPase-coupled intramembrane lipopolysaccharide transporter activity|lipopolysaccharide-transporting ATPase activity|ATP-dependent intramembrane lipopolysaccharide transporter activity|LPS-transporting ATPase activity|lipopolysaccharide floppase activity (cytosolic to exoplasmic leaftlet) http://purl.obolibrary.org/obo/GO_0015437 GO:0015438 biolink:MolecularActivity ABC-type teichoic acid transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out). MetaCyc:3.6.3.40-RXN|EC:7.5.2.4 go-plus.json teichoic-acid-transporting ATPase activity|teichoic acid transmembrane transporter activity|ABC-type teichoic-acid transporter|ATPase-coupled teichoic acid transmembrane transporter activity|ATP-dependent teichoic acid transmembrane transporter activity|teichoic-acid ABC transporter http://purl.obolibrary.org/obo/GO_0015438 GO:0015439 biolink:MolecularActivity ABC-type heme transporter activity Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out). MetaCyc:TRANS-RXN0-162|RHEA:19261|MetaCyc:3.6.3.41-RXN|Reactome:R-HSA-382560|EC:7.6.2.5|Reactome:R-HSA-1369065|Reactome:R-HSA-917979|Reactome:R-HSA-5683355 go-plus.json protoheme IX ABC transporter activity|haem-transporting ATPase activity|ATP-dependent heme transmembrane transporter activity|heme ABC transporter|ATPase-coupled heme transmembrane transporter activity|ATPase-coupled heme transporter activity|heme-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015439 GO:0015432 biolink:MolecularActivity ABC-type bile acid transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate. Reactome:R-HSA-193362|Reactome:R-HSA-5678517|RHEA:50048|Reactome:R-HSA-194153|TC:3.A.1.207.2 go-plus.json bile acid porter activity|bile acid-exporting ATPase activity|ATPase-coupled bile acid transmembrane transporter activity|ATP-dependent bile acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015432 GO:0015433 biolink:MolecularActivity ABC-type peptide antigen transporter activity Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate. Reactome:R-HSA-983144|Reactome:R-HSA-1236949|TC:3.A.1.209.1 go-plus.json peptide antigen-transporting ATPase activity|major histocompatibility peptide transporter activity|peptide antigen ABC transporter|ATP-dependent peptide antigen transmembrane transporter activity|peptide antigen transporter activity|ATPase-coupled peptide antigen transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015433 GO:0015434 biolink:MolecularActivity ABC-type cadmium transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole). MetaCyc:3.6.3.46-RXN|EC:7.2.2.2 go-plus.json ATPase-coupled cadmium transmembrane transporter activity|cadmium ABC transporter|ATP-dependent cadmium transmembrane transporter activity|cadmium-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015434 CHEBI:134567 biolink:ChemicalSubstance diacylglycerol (18:1/0:0/18:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134567 chebi_ph7_3 GO:0015435 biolink:MolecularActivity obsolete ABC-type efflux permease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ABC-type efflux permease activity http://purl.obolibrary.org/obo/GO_0015435 CHEBI:76342 biolink:ChemicalSubstance (S)-3-hydroxydodecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76342 chebi_ph7_3 PR:000004716 biolink:Protein brain-derived neurotrophic factor A neurotrophin that is a translation product of the human BDNF gene or a 1:1 ortholog thereof. go-plus.json BDNF|abrineurin http://purl.obolibrary.org/obo/PR_000004716 GO:0015430 biolink:MolecularActivity ABC-type glycerol-3-phosphate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in). MetaCyc:3.6.3.20-RXN|RHEA:21668|EC:7.6.2.10 go-plus.json ATP-dependent glycerol-2-phosphate transmembrane transporter activity|ATPase-coupled glycerol-2-phosphate transmembrane transporter activity|ABC-type glycerol 3-phosphate transporter|glycerol-2-phosphate-transporting ATPase activity|ATPase-coupled glycerol-3-phosphate transmembrane transporter activity|glycerol-3-phosphate ABC transporter|glycerol-phosphate porter activity|glycerol-3-phosphate-transporting ATPase|glycerol phosphate-importing ATPase activity http://purl.obolibrary.org/obo/GO_0015430 CHEBI:76340 biolink:ChemicalSubstance trans-2-dodecenedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76340 chebi_ph7_3 GO:0015431 biolink:MolecularActivity ABC-type glutathione S-conjugate transporter activity Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out). RHEA:19121|EC:7.6.2.3 go-plus.json ATPase-coupled glutathione S-conjugate transmembrane transporter activity|conjugate transporter activity|glutathione S-conjugate-transporting ATPase activity|GS-X pump|ATP-dependent glutathione S-conjugate export pump|glutathione S-conjugate-exporting ATPase activity|MRP1/GS-X pump http://purl.obolibrary.org/obo/GO_0015431 CHEBI:76346 biolink:ChemicalSubstance 3-oxododecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76346 chebi_ph7_3 CHEBI:76347 biolink:ChemicalSubstance trans-2-decenedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76347 chebi_ph7_3 CHEBI:76345 biolink:ChemicalSubstance decanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76345 GO:1990101 biolink:CellularComponent DnaA-oriC complex A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle. go-plus.json DnaA-DNA complex http://purl.obolibrary.org/obo/GO_1990101 GO:1990102 biolink:CellularComponent DnaA-DiaA complex A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA. go-plus.json DnaA-DiaA-DNA complex http://purl.obolibrary.org/obo/GO_1990102 GO:1990103 biolink:CellularComponent DnaA-HU complex A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC. go-plus.json DnaA-HU-DNA complex http://purl.obolibrary.org/obo/GO_1990103 GO:1990104 biolink:CellularComponent DNA bending complex A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction. go-plus.json histone-like DNA binding complex http://purl.obolibrary.org/obo/GO_1990104 GO:1990100 biolink:CellularComponent DnaB-DnaC complex A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC). go-plus.json DnaB6-DnaC6 complex|DnaB6-DnaC3 complex|helicase-loading complex http://purl.obolibrary.org/obo/GO_1990100 GO:0015447 biolink:MolecularActivity obsolete type II protein secretor activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json type II protein secretor activity http://purl.obolibrary.org/obo/GO_0015447 GO:0015448 biolink:MolecularActivity obsolete type III protein (virulence-related) secretor activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json type III protein (virulence-related) secretor activity http://purl.obolibrary.org/obo/GO_0015448 GO:0015449 biolink:MolecularActivity obsolete type IV protein (DNA-protein) secretor activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json type IV protein (DNA-protein) secretor activity http://purl.obolibrary.org/obo/GO_0015449 CHEBI:134574 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(38:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134574 GO:0015443 biolink:MolecularActivity obsolete sodium-transporting two-sector ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). go-plus.json sodium-transporting two-sector ATPase activity http://purl.obolibrary.org/obo/GO_0015443 GO:0015444 biolink:MolecularActivity P-type magnesium transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in). EC:7.2.2.14|MetaCyc:3.6.3.2-RXN|RHEA:10260 go-plus.json magnesium importing ATPase activity|magnesium-translocating P-type ATPase activity|Mg(2+)-importing ATPase activity|ATP phosphohydrolase (Mg2+-importing)|Mg2+-importing ATPase activity|magnesium transmembrane transporter activity, phosphorylative mechanism http://purl.obolibrary.org/obo/GO_0015444 GO:0015445 biolink:MolecularActivity P-type silver transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out). EC:7.2.2.15|RHEA:14733|MetaCyc:3.6.3.53-RXN go-plus.json silver exporting ATPase activity|silver transmembrane transporter activity, phosphorylative mechanism|ATP phosphohydrolase (Ag+-exporting)|silver-exporting ATPase activity|Ag+-exporting ATPase activity http://purl.obolibrary.org/obo/GO_0015445 GO:0015446 biolink:MolecularActivity ATPase-coupled arsenite transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out). RHEA:11348|EC:7.3.2.7|TC:3.A.4.1.1|MetaCyc:3.6.3.16-RXN go-plus.json arsenite-transporting ATPase activity|arsenite-translocating ATPase activity|arsenite-transmembrane transporting ATPase activity|arsenite ABC transporter|arsenical pump-driving ATPase activity|arsenite transporting ATPase activity|arsenical resistance efflux pump|arsenical resistance ATPase activity http://purl.obolibrary.org/obo/GO_0015446 GO:1990109 biolink:BiologicalProcess rejection of pollen from other species The process involved in the rejection of pollen of one species by cells in the stigma of another species. go-plus.json unilateral interspecific incompatibility http://purl.obolibrary.org/obo/GO_1990109 GO:0015440 biolink:MolecularActivity ABC-type peptide transporter activity Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria. RHEA:14429|EC:7.4.2.5|MetaCyc:3.6.3.43-RXN go-plus.json peptide-transporting ATPase activity|peptide ABC transporter|ATPase-coupled peptide transmembrane transporter activity|ATP-dependent peptide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015440 GO:0015441 biolink:MolecularActivity ABC-type beta-glucan transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out). EC:7.5.2.3|RHEA:18453|MetaCyc:3.6.3.42-RXN go-plus.json ATPase-coupled beta-glucan transporter activity|ATP-dependent beta-glucan transporter activity|beta-glucan-transporting ATPase activity|ABC-type beta-glucan transporter|beta-glucan ABC transporter http://purl.obolibrary.org/obo/GO_0015441 CHEBI:76352 biolink:ChemicalSubstance octanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_76352 GO:0015442 biolink:MolecularActivity obsolete hydrogen-/sodium-translocating ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out). go-plus.json proton-/sodium-translocating ATPase activity|hydrogen-/sodium-translocating ATPase activity http://purl.obolibrary.org/obo/GO_0015442 GO:1990105 biolink:BiologicalProcess obsolete regulation of voltage-gated potassium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity. go-plus.json regulation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_1990105 CHEBI:134572 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(34:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134572 GO:1990106 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990106 GO:1990107 biolink:MolecularActivity thiazole synthase activity Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O. RHEA:26297 go-plus.json 1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity http://purl.obolibrary.org/obo/GO_1990107 GO:1990108 biolink:BiologicalProcess protein linear deubiquitination A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990108 CHEBI:76356 biolink:ChemicalSubstance (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76356 chebi_ph7_3 UBERON:0019196 biolink:AnatomicalEntity iliac artery endothelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0019196 CHEBI:17947 biolink:ChemicalSubstance 3-dehydroquinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17947 CHEBI:17948 biolink:ChemicalSubstance (+)-taxifolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17948 chebi_ph7_3 CHEBI:17945 biolink:ChemicalSubstance N-cyclohexylformamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17945 chebi_ph7_3 CHEBI:17943 biolink:ChemicalSubstance (S)-2-O-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17943 CHEBI:17941 biolink:ChemicalSubstance diisopropyl fluorophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17941 chebi_ph7_3 CHEBI:17942 biolink:ChemicalSubstance D-allose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17942 UBERON:0019190 biolink:AnatomicalEntity mucous gland of lung go-plus.json peribronchial gland|bronchial mucous gland|bronchial gland http://purl.obolibrary.org/obo/UBERON_0019190 UBERON:0019189 biolink:AnatomicalEntity carotid artery endothelium go-plus.json carotid epithelium|carotid endothelium http://purl.obolibrary.org/obo/UBERON_0019189 CHEBI:17938 biolink:ChemicalSubstance 5alpha-ergosta-7,22-diene-3beta,5-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17938 chebi_ph7_3 CHEBI:17939 biolink:ChemicalSubstance puromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17939 CHEBI:17936 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17936 CHEBI:17937 biolink:ChemicalSubstance L-rhamnono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17937 chebi_ph7_3 CHEBI:17934 biolink:ChemicalSubstance pregnan-21-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_17934 chebi_ph7_3 CHEBI:17935 biolink:ChemicalSubstance octanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17935 chebi_ph7_3 CHEBI:17933 biolink:ChemicalSubstance calcidiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17933 chebi_ph7_3 CHEBI:17931 biolink:ChemicalSubstance N-hydroxy-2-acetamidofluorene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17931 chebi_ph7_3 CHEBI:42905 biolink:ChemicalSubstance alpha-L-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_42905 chebi_ph7_3 CHEBI:17969 biolink:ChemicalSubstance sedoheptulose 1,7-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17969 CHEBI:66904 biolink:ChemicalSubstance 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_66904 CHEBI:17967 biolink:ChemicalSubstance urethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_17967 chebi_ph7_3 CHEBI:66905 biolink:ChemicalSubstance aureusidin 6-O-beta-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_66905 chebi_ph7_3 CHEBI:17968 biolink:ChemicalSubstance butyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17968 chebi_ph7_3 CHEBI:66906 biolink:ChemicalSubstance 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_66906 CHEBI:17965 biolink:ChemicalSubstance isoorientin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17965 CHEBI:17966 biolink:ChemicalSubstance cyclohexyl isocyanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17966 CHEBI:17964 biolink:ChemicalSubstance pipecolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17964 CHEBI:17961 biolink:ChemicalSubstance farnesyl triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17961 CHEBI:17962 biolink:ChemicalSubstance CDP-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17962 CHEBI:17960 biolink:ChemicalSubstance 3-oxopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17960 CHEBI:66907 biolink:ChemicalSubstance bracteatin 6-O-beta-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_66907 chebi_ph7_3 CHEBI:66909 biolink:ChemicalSubstance alpha-D-Glcp-(1->3)-L-Rhap go-plus.json http://purl.obolibrary.org/obo/CHEBI_66909 chebi_ph7_3 CHEBI:66914 biolink:ChemicalSubstance UDP-alpha-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66914 chebi_ph7_3 CHEBI:17958 biolink:ChemicalSubstance alkyl cinnamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17958 chebi_ph7_3 CHEBI:66915 biolink:ChemicalSubstance UDP-alpha-D-galactofuranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66915 chebi_ph7_3 CHEBI:17959 biolink:ChemicalSubstance oxidized Renilla luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17959 chebi_ph7_3 CHEBI:66916 biolink:ChemicalSubstance alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_66916 chebi_ph7_3 CHEBI:17957 biolink:ChemicalSubstance 5-(2-hydroxyethyl)-4-methylthiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_17957 chebi_ph7_3 CHEBI:17954 biolink:ChemicalSubstance 1-alpha-D-galactosyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17954 CHEBI:17955 biolink:ChemicalSubstance 2'-deoxyribonucleoside diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17955 CHEBI:66911 biolink:ChemicalSubstance alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66911 chebi_ph7_3 CHEBI:17952 biolink:ChemicalSubstance flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]s go-plus.json http://purl.obolibrary.org/obo/CHEBI_17952 chebi_ph7_3 CHEBI:66912 biolink:ChemicalSubstance alpha-D-abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66912 chebi_ph7_3 CHEBI:17953 biolink:ChemicalSubstance xanthopterin-B2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_17953 chebi_ph7_3 CHEBI:17950 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17950 chebi_ph7_3 CHEBI:66918 biolink:ChemicalSubstance ergosta-5,7-dien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_66918 chebi_ph7_3 CHEBI:17907 biolink:ChemicalSubstance styrene oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17907 chebi_ph7_3 CHEBI:17905 biolink:ChemicalSubstance coenzyme M go-plus.json http://purl.obolibrary.org/obo/CHEBI_17905 CHEBI:17906 biolink:ChemicalSubstance aminoacetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17906 CHEBI:17903 biolink:ChemicalSubstance 4-(dimethylamino)azobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17903 chebi_ph7_3 CHEBI:17901 biolink:ChemicalSubstance 6-O-acetyl-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17901 chebi_ph7_3 CHEBI:17902 biolink:ChemicalSubstance N-carbamoylputrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17902 CHEBI:66922 biolink:ChemicalSubstance citrullinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66922 OBO:uberon/core#protects biolink:OntologyClass protects protects go-plus.json http://purl.obolibrary.org/obo/uberon/core#protects CHEBI:66924 biolink:ChemicalSubstance creatinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66924 CHEBI:66929 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_66929 CHEBI:66936 biolink:ChemicalSubstance (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66936 CHEBI:66937 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66937 chebi_ph7_3 CHEBI:66938 biolink:ChemicalSubstance keto-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66938 CHEBI:66939 biolink:ChemicalSubstance (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66939 CHEBI:66933 biolink:ChemicalSubstance N-alkylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_66933 CHEBI:66934 biolink:ChemicalSubstance cyanoamino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_66934 CHEBI:6104 biolink:ChemicalSubstance kanamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6104 CHEBI:66940 biolink:ChemicalSubstance fructosylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66940 CHEBI:66941 biolink:ChemicalSubstance ecgononium methyl ester(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66941 chebi_ph7_3 CHEBI:66942 biolink:ChemicalSubstance 4-oxo-4-(pyridin-3-yl)butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66942 chebi_ph7_3 CHEBI:17929 biolink:ChemicalSubstance N(omega),N(omega)-dimethyl-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17929 CHEBI:17927 biolink:ChemicalSubstance N(1)-acetylspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17927 CHEBI:17928 biolink:ChemicalSubstance 1-amino-1-deoxy-scyllo-inositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17928 CHEBI:66947 biolink:ChemicalSubstance (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66947 chebi_ph7_3 CHEBI:17925 biolink:ChemicalSubstance alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17925 chebi_ph7_3 CHEBI:66948 biolink:ChemicalSubstance isoglutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66948 chebi_ph7_3 CHEBI:17926 biolink:ChemicalSubstance hydrogenobyrinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17926 CHEBI:66949 biolink:ChemicalSubstance nucleoside 3'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66949 chebi_ph7_3 CHEBI:17924 biolink:ChemicalSubstance D-glucitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17924 chebi_ph7_3 CHEBI:17922 biolink:ChemicalSubstance fluoren-9-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17922 chebi_ph7_3 CHEBI:66944 biolink:ChemicalSubstance 2,6-dihydroxypseudooxynicotinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66944 chebi_ph7_3 CHEBI:66945 biolink:ChemicalSubstance 4-nitro-6-oxohepta-2,4-dienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66945 chebi_ph7_3 CHEBI:17920 biolink:ChemicalSubstance 3-methyleneoxindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_17920 chebi_ph7_3 CHEBI:66946 biolink:ChemicalSubstance 4-(6-hydroxypyridin-3-yl)-4-oxobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66946 CHEBI:66950 biolink:ChemicalSubstance olivetolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66950 chebi_ph7_3 CHEBI:66951 biolink:ChemicalSubstance 4-oxo-4-(pyridin-3-yl)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66951 CHEBI:66952 biolink:ChemicalSubstance homocysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66952 CHEBI:66953 biolink:ChemicalSubstance 5-oxo-1,2-campholide go-plus.json http://purl.obolibrary.org/obo/CHEBI_66953 chebi_ph7_3 CHEBI:17919 biolink:ChemicalSubstance 3-mercapto-2-mercaptomethylpropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17919 CHEBI:17917 biolink:ChemicalSubstance L-allysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17917 CHEBI:66958 biolink:ChemicalSubstance 4-hydroxy-6-pentylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_66958 chebi_ph7_3 CHEBI:17915 biolink:ChemicalSubstance hexano-6-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17915 chebi_ph7_3 GO:0039599 biolink:BiologicalProcess cleavage by virus of host mRNA Any process in which a host pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner by a viral endoribonuclease. go-plus.json viral endoribonuclease activity involved in degradation of host mRNA|host mRNA cleavage by viral endoribonuclease http://purl.obolibrary.org/obo/GO_0039599 CHEBI:17913 biolink:ChemicalSubstance streptidine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17913 CHEBI:66954 biolink:ChemicalSubstance 2',3'-cyclic nucleotide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66954 chebi_ph7_3 CHEBI:66955 biolink:ChemicalSubstance olivetolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66955 CHEBI:66956 biolink:ChemicalSubstance antidyskinesia agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_66956 CHEBI:66957 biolink:ChemicalSubstance 3,5,7-trioxododecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66957 chebi_ph7_3 GO:0039593 biolink:BiologicalProcess suppression by virus of host exit from mitosis Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. VZ:877 go-plus.json inhibition of host mitotic exit by virus http://purl.obolibrary.org/obo/GO_0039593 GO:0039594 biolink:MolecularActivity endoribonuclease activity involved in viral induction of host mRNA catabolic process Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0039594 GO:0039591 biolink:BiologicalProcess suppression by virus of host tapasin activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host tapasin (TAP binding protein/TAPBP) activity. Tapasin is a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response. VZ:818 go-plus.json inhibition of host TAPBP by virus|inhibition of host tapasin by virus|suppression by virus of host TAP binding protein http://purl.obolibrary.org/obo/GO_0039591 GO:0039592 biolink:BiologicalProcess suppression by virus of G2/M transition of host mitotic cell cycle Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle. VZ:876 go-plus.json host G2/M cell cycle arrest by virus http://purl.obolibrary.org/obo/GO_0039592 GO:0039597 biolink:BiologicalProcess obsolete induction by virus of host endoribonuclease activity OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity. go-plus.json viral induction of host RNAse activity http://purl.obolibrary.org/obo/GO_0039597 GO:0039598 biolink:BiologicalProcess obsolete induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process OBSOLETE. The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA) initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA. go-plus.json induction by virus of host nuclear poly(A)-dependent mRNA catabolic process|virus-mediated host mRNA decay by hyperadenylation|induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process http://purl.obolibrary.org/obo/GO_0039598 GO:0039595 biolink:BiologicalProcess induction by virus of catabolism of host mRNA The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA). VZ:901 go-plus.json promotion of host mRNA degradation|viral induction of host mRNA decay|virus-mediated mRNA decay|induction by virus of host mRNA catabolic process|induction of host mRNA decay http://purl.obolibrary.org/obo/GO_0039595 GO:0039596 biolink:BiologicalProcess modulation by virus of host protein dephosphorylation Any viral process that modulates the frequency, rate or extent of dephosphorylation of a host protein. go-plus.json http://purl.obolibrary.org/obo/GO_0039596 CHEBI:52317 biolink:ChemicalSubstance thalianol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52317 chebi_ph7_3 CL:0000402 biolink:Cell CNS interneuron go-plus.json http://purl.obolibrary.org/obo/CL_0000402 CHEBI:27353 biolink:ChemicalSubstance xylulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27353 CHEBI:27354 biolink:ChemicalSubstance xylulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27354 CL:0000404 biolink:Cell electrically signaling cell A cell that initiates an electrical signal and passes that signal to another cell. go-plus.json http://purl.obolibrary.org/obo/CL_0000404 CHEBI:27355 biolink:ChemicalSubstance xylulose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27355 CHEBI:27350 biolink:ChemicalSubstance xyloside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27350 CL:0000408 biolink:Cell male gamete go-plus.json http://purl.obolibrary.org/obo/CL_0000408 CHEBI:27351 biolink:ChemicalSubstance xylosylgalactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_27351 CHEBI:6151 biolink:ChemicalSubstance (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_6151 CHEBI:52303 biolink:ChemicalSubstance sterol methyltransferase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_52303 CHEBI:27369 biolink:ChemicalSubstance zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_27369 CL:0000413 biolink:Cell haploid cell A cell whose nucleus contains a single haploid genome. go-plus.json http://purl.obolibrary.org/obo/CL_0000413 CHEBI:27364 biolink:ChemicalSubstance zinc molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_27364 CHEBI:27365 biolink:ChemicalSubstance zinc ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_27365 CL:0000417 biolink:Cell endopolyploid cell go-plus.json http://purl.obolibrary.org/obo/CL_0000417 UBERON:0034763 biolink:AnatomicalEntity hindbrain commissure Any commissure within the hindbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034763 CHEBI:27362 biolink:ChemicalSubstance zeta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27362 chebi_ph7_3 CHEBI:27363 biolink:ChemicalSubstance zinc atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27363 chebi_ph7_3 CHEBI:42989 biolink:ChemicalSubstance 7beta-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42989 chebi_ph7_3 CL:0000412 biolink:Cell polyploid cell A cell whose nucleus, or nuclei, each contain more than two haploid genomes. go-plus.json http://purl.obolibrary.org/obo/CL_0000412 CHEBI:27338 biolink:ChemicalSubstance xylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27338 UBERON:0009777 biolink:AnatomicalEntity intermediate reticular nucleus A nucleus of brain that is part of a intermediate reticular formation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009777 UBERON:0010755 biolink:AnatomicalEntity secondary follicle corona The part of the secondary follicle that surrounds the germinal center. go-plus.json B cell corona|dark zone of follicle|peripheral zone of follicle|mantle zone|inactive zone of follicle http://purl.obolibrary.org/obo/UBERON_0010755 UBERON:0009778 biolink:AnatomicalEntity pleural sac A serous sac that has the pleura and the pleural cavity as parts. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009778 UBERON:0034768 biolink:AnatomicalEntity morphological feature A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034768 UBERON:0010753 biolink:AnatomicalEntity lymph node secondary follicle A secondary follicle that is located in a lymph node go-plus.json http://purl.obolibrary.org/obo/UBERON_0010753 UBERON:0010754 biolink:AnatomicalEntity germinal center A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. go-plus.json reaction center of follicle|nodule|lymhpoid nodule|central zone of follice|light zone of follicle http://purl.obolibrary.org/obo/UBERON_0010754 UBERON:0034769 biolink:AnatomicalEntity lymphomyeloid tissue go-plus.json http://purl.obolibrary.org/obo/UBERON_0034769 CHEBI:42977 biolink:ChemicalSubstance 25-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_42977 chebi_ph7_3 UBERON:0010758 biolink:AnatomicalEntity subdivision of organism along appendicular axis A major subdivision of an organism that divides an organism along an axis perpedicular to the main body anterior-posterior axis. In vertebrates, this is typically a fin or limb segment. In insects, this includes segments of appendages such as antennae, as well as segments of the insect leg. go-plus.json appendage segment|appendicular segment http://purl.obolibrary.org/obo/UBERON_0010758 UBERON:0009773 biolink:AnatomicalEntity renal tubule A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. go-plus.json renal tubule (generic)|tubule of excretory system http://purl.obolibrary.org/obo/UBERON_0009773 UBERON:0009775 biolink:AnatomicalEntity lateral medullary reticular complex A nuclear complex of the medullary reticular formation that can be divided into three subnuclei: the parvocellular, magnocellular and the subtrigeminal[WP,modified]. go-plus.json nuclei laterales myelencephali|lateral medullary reticular group|lateral group of medullary reticular formation|lateral reticular formation of the medulla oblongata http://purl.obolibrary.org/obo/UBERON_0009775 UBERON:0009776 biolink:AnatomicalEntity intermediate reticular formation . go-plus.json intermediate reticular formations http://purl.obolibrary.org/obo/UBERON_0009776 CHEBI:27346 biolink:ChemicalSubstance xylonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_27346 CHEBI:27347 biolink:ChemicalSubstance xylonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27347 CHEBI:27349 biolink:ChemicalSubstance xylose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27349 CHEBI:27343 biolink:ChemicalSubstance xylogalacturonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_27343 CHEBI:27345 biolink:ChemicalSubstance xylonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27345 NCBITaxon:40551 biolink:OrganismalEntity Arecales go-plus.json Areciflorae http://purl.obolibrary.org/obo/NCBITaxon_40551 CHEBI:27341 biolink:ChemicalSubstance xylitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27341 UBERON:0009767 biolink:AnatomicalEntity proximal interphalangeal joint An inter-phalangeal joint that connects a proximal phalanx to either a medial or distal phalanx. go-plus.json PIP joint|PIJ joint http://purl.obolibrary.org/obo/UBERON_0009767 UBERON:0009768 biolink:AnatomicalEntity distal interphalangeal joint An inter-phalangeal joint that connects a distal phalanx to either a medial or proximal phalanx. go-plus.json DIP joint|DIJ joint http://purl.obolibrary.org/obo/UBERON_0009768 UBERON:0010742 biolink:AnatomicalEntity bone of pelvic complex A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle. go-plus.json hindlimb bone http://purl.obolibrary.org/obo/UBERON_0010742 UBERON:0010743 biolink:AnatomicalEntity meningeal cluster The collection of all meningeal layers that line a central nervous system. go-plus.json cluster of meninges|meninges|cerebral meninges http://purl.obolibrary.org/obo/UBERON_0010743 UBERON:0010748 biolink:AnatomicalEntity lymph node follicle A lymphoid follicle that is part of a lymph node. go-plus.json follicle of lymph node http://purl.obolibrary.org/obo/UBERON_0010748 CHEBI:6121 biolink:ChemicalSubstance ketamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_6121 CHEBI:27314 biolink:ChemicalSubstance water-soluble vitamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27314 NCBITaxon:5664 biolink:OrganismalEntity Leishmania major go-plus.json Leishmania tropica major|Leishmania (Leishmania) major http://purl.obolibrary.org/obo/NCBITaxon_5664 CHEBI:27311 biolink:ChemicalSubstance volatile oil component go-plus.json http://purl.obolibrary.org/obo/CHEBI_27311 UBERON:0034710 biolink:AnatomicalEntity spinal cord ventricular layer go-plus.json spinal cord lateral wall ventricular layer http://purl.obolibrary.org/obo/UBERON_0034710 CHEBI:17989 biolink:ChemicalSubstance daphnin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17989 chebi_ph7_3 CHEBI:17987 biolink:ChemicalSubstance benzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17987 chebi_ph7_3 UBERON:0034705 biolink:AnatomicalEntity developing neuroepithelium An embryonic or larval epithelium that is committed to form part of the nervous system. go-plus.json neuroepithelium|embryonic neuroepithelium|neurepithelium http://purl.obolibrary.org/obo/UBERON_0034705 UBERON:0034706 biolink:AnatomicalEntity proliferating neuroepithelium An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034706 CHEBI:17985 biolink:ChemicalSubstance adenosine 3',5'-bismonophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17985 UBERON:0034707 biolink:AnatomicalEntity differentiating neuroepithelium A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034707 UBERON:0034708 biolink:AnatomicalEntity cerebellum marginal layer go-plus.json marginal zone of cerebellum|MZCB http://purl.obolibrary.org/obo/UBERON_0034708 CHEBI:17983 biolink:ChemicalSubstance UDP-L-arabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17983 UBERON:0034709 biolink:AnatomicalEntity hindbrain marginal layer go-plus.json marginal zone of hindbrain|MZH http://purl.obolibrary.org/obo/UBERON_0034709 CHEBI:17984 biolink:ChemicalSubstance acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_17984 CHEBI:17981 biolink:ChemicalSubstance O-acetyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17981 CHEBI:17982 biolink:ChemicalSubstance 6-acetamido-3-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17982 chebi_ph7_3 CHEBI:17980 biolink:ChemicalSubstance 3'-phospho-5'-adenylyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17980 CHEBI:6178 biolink:ChemicalSubstance L-arabinofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_6178 chebi_ph7_3 CHEBI:27329 biolink:ChemicalSubstance xanthosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27329 UBERON:0019143 biolink:AnatomicalEntity intramuscular adipose tissue Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes. go-plus.json intramuscular fat http://purl.obolibrary.org/obo/UBERON_0019143 CHEBI:27325 biolink:ChemicalSubstance xanthophyll go-plus.json http://purl.obolibrary.org/obo/CHEBI_27325 CHEBI:27323 biolink:ChemicalSubstance xanthommatins go-plus.json http://purl.obolibrary.org/obo/CHEBI_27323 UBERON:0034720 biolink:AnatomicalEntity head taste bud A taste bud that is located on the skin of the head. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034720 UBERON:0034721 biolink:AnatomicalEntity pharyngeal taste bud A taste bud that is located in the pharynx. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034721 UBERON:0034711 biolink:AnatomicalEntity cortical preplate The layer of the developing cerebral cortex that is formed from the first cohort of neurons to migrate out of the cortical ventricular zone; split by the second wave into marginal zone and subplate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034711 UBERON:0034713 biolink:AnatomicalEntity cranial neuron projection bundle Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain go-plus.json neuron projection bundle from brain|cranial nerve or tract|cranial nerve fiber bundle|cranial nerve fiber tract http://purl.obolibrary.org/obo/UBERON_0034713 CHEBI:17978 biolink:ChemicalSubstance 5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17978 UBERON:0034714 biolink:AnatomicalEntity epiphyseal tract A cranial nerve fiber tract that innervates the parietal eye. go-plus.json epiphyseal nerve http://purl.obolibrary.org/obo/UBERON_0034714 CHEBI:17979 biolink:ChemicalSubstance aldehydo-L-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17979 chebi_ph7_3 CHEBI:17976 biolink:ChemicalSubstance ubiquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17976 chebi_ph7_3 UBERON:0034715 biolink:AnatomicalEntity pineal tract A cranial nerve fiber tract that innervates the pineal body. go-plus.json pineal nerve http://purl.obolibrary.org/obo/UBERON_0034715 CHEBI:17977 biolink:ChemicalSubstance 1,4-benzosemiquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17977 chebi_ph7_3 UBERON:0034717 biolink:AnatomicalEntity integumental taste bud A taste bud that is located external to the digestive tube, on the head or body, as found in species such as goldfish. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034717 CHEBI:17975 biolink:ChemicalSubstance 5,10-(methanylylidene)tetrahydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17975 UBERON:0034719 biolink:AnatomicalEntity lip taste bud A taste bud that is located on a lip. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034719 CHEBI:17972 biolink:ChemicalSubstance ribonucleoside triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17972 CHEBI:17973 biolink:ChemicalSubstance alpha-D-galactose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17973 CHEBI:17970 biolink:ChemicalSubstance N-acyl-D-mannosaminolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17970 chebi_ph7_3 UBERON:0034730 biolink:AnatomicalEntity olfactory tract linking bulb to ipsilateral dorsal telencephalon go-plus.json lateral olfactory tract|tractus olfactorius lateralis http://purl.obolibrary.org/obo/UBERON_0034730 UBERON:0034722 biolink:AnatomicalEntity mouth roof taste bud A taste bud that is located on the roof of the mouth. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034722 UBERON:0034723 biolink:AnatomicalEntity fin taste bud A taste bud that is located on a fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034723 UBERON:0034724 biolink:AnatomicalEntity esophageal taste bud A taste bud that is located in the esophagus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034724 UBERON:0034726 biolink:AnatomicalEntity trunk taste bud A taste bud that is located on the skin of the trunk. go-plus.json http://purl.obolibrary.org/obo/UBERON_0034726 UBERON:0034728 biolink:AnatomicalEntity autonomic nerve The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa. go-plus.json visceral nerve|nervus visceralis http://purl.obolibrary.org/obo/UBERON_0034728 UBERON:0034729 biolink:AnatomicalEntity sympathetic nerve go-plus.json http://purl.obolibrary.org/obo/UBERON_0034729 CHEBI:42939 biolink:ChemicalSubstance cyclohexylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_42939 chebi_ph7_3 CHEBI:27306 biolink:ChemicalSubstance vitamin B6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_27306 NCBITaxon:5658 biolink:OrganismalEntity Leishmania go-plus.json Leishmania http://purl.obolibrary.org/obo/NCBITaxon_5658 NCBITaxon:5653 biolink:OrganismalEntity Kinetoplastea go-plus.json kinetoplastids|kinetoplasts|Protomonadida|Kinetoplastida http://purl.obolibrary.org/obo/NCBITaxon_5653 NCBITaxon:5654 biolink:OrganismalEntity Trypanosomatidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5654 CHEBI:27300 biolink:ChemicalSubstance vitamin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_27300 CHEBI:17998 biolink:ChemicalSubstance 4-methylpentanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17998 chebi_ph7_3 CHEBI:17996 biolink:ChemicalSubstance chloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_17996 chebi_ph7_3 CHEBI:17997 biolink:ChemicalSubstance dinitrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_17997 chebi_ph7_3 CHEBI:17994 biolink:ChemicalSubstance D-ribose 1,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17994 CHEBI:17992 biolink:ChemicalSubstance sucrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17992 chebi_ph7_3 CHEBI:17993 biolink:ChemicalSubstance 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17993 CHEBI:17990 biolink:ChemicalSubstance 1-O-(indol-3-ylacetyl)-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17990 chebi_ph7_3 GO:1990079 biolink:BiologicalProcess cartilage homeostasis A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function. go-plus.json negative regulation of cartilage homeostasis|regulation of cartilage homeostasis|positive regulation of cartilage homeostasis http://purl.obolibrary.org/obo/GO_1990079 GO:1990075 biolink:CellularComponent periciliary membrane compartment A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis. go-plus.json PCMC http://purl.obolibrary.org/obo/GO_1990075 GO:1990076 biolink:BiologicalProcess cell wall polysaccharide catabolic process involved in abscission Any cell wall polysaccharide catabolic process that is involved in abscission. go-plus.json http://purl.obolibrary.org/obo/GO_1990076 GO:1990077 biolink:CellularComponent primosome complex Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart. go-plus.json primosome http://purl.obolibrary.org/obo/GO_1990077 GO:1990078 biolink:CellularComponent replication inhibiting complex A protein complex that inhibits multiple events of replication initiation during one replication cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1990078 GO:1990071 biolink:CellularComponent TRAPPII protein complex A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself. go-plus.json http://purl.obolibrary.org/obo/GO_1990071 GO:1990072 biolink:CellularComponent TRAPPIII protein complex A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins. go-plus.json http://purl.obolibrary.org/obo/GO_1990072 GO:0039508 biolink:BiologicalProcess suppression by virus of host receptor activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host receptor. go-plus.json inhibition by virus of host receptor activity|viral inhibition of host receptor|suppression by virus of host receptor function|downregulation by virus of host receptor activity|negative regulation by virus of host receptor activity|down-regulation by virus of host receptor activity http://purl.obolibrary.org/obo/GO_0039508 GO:1990073 biolink:CellularComponent perforation plate A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations). go-plus.json http://purl.obolibrary.org/obo/GO_1990073 GO:0039509 biolink:BiologicalProcess suppression by virus of host pattern recognition receptor activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host pattern recognition receptor. A pattern recognition receptor combines with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. go-plus.json down regulation by virus of host pattern recognition receptor activity|suppression by virus of host pattern recognition receptor function|inhibition by virus of host pattern recognition receptor activity|negative regulation by virus of host pattern recognition receptor activity|down-regulation by virus of host pattern recognition receptor activity|viral inhibition of host pattern recognition receptor activity http://purl.obolibrary.org/obo/GO_0039509 GO:1990074 biolink:BiologicalProcess polyuridylation-dependent mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990074 GO:0015539 biolink:MolecularActivity hexuronate:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate. go-plus.json hexuronate porter activity|hexuronate (glucuronate/galacturonate) porter activity http://purl.obolibrary.org/obo/GO_0015539 GO:1990070 biolink:CellularComponent TRAPPI protein complex A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast. go-plus.json TRAPP core complex http://purl.obolibrary.org/obo/GO_1990070 GO:0039502 biolink:BiologicalProcess suppression by virus of host type I interferon-mediated signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. VZ:883 go-plus.json inhibition of host interferon signaling pathway by virus|suppression by virus of host type I interferon-mediated signalling pathway|suppression by virus of host type I IFN-mediated signaling pathway|negative regulation by virus of host type I interferon-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0039502 CL:0000482 biolink:Cell juvenile hormone secreting cell An endocrine cell that secretes juvenile hormone. go-plus.json http://purl.obolibrary.org/obo/CL_0000482 GO:0015535 biolink:MolecularActivity fucose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in). RHEA:29023 go-plus.json fucose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015535 CHEBI:134664 biolink:ChemicalSubstance N-hydroxy-L-dihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134664 chebi_ph7_3 GO:0039503 biolink:BiologicalProcess suppression by virus of host innate immune response Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense. go-plus.json inhibition of host innate immune response by virus|negative regulation by virus of host innate immune response|negative regulation by virus of host innate immunity|suppression by virus of host innate immunity http://purl.obolibrary.org/obo/GO_0039503 GO:0015536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015536 CHEBI:134665 biolink:ChemicalSubstance N,N-dihydroxy-L-dihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134665 chebi_ph7_3 GO:0015537 biolink:MolecularActivity xanthosine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in). go-plus.json xanthosine:hydrogen ion symporter activity|xanthosine permease activity http://purl.obolibrary.org/obo/GO_0015537 CL:0000484 biolink:Cell connective tissue type mast cell Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. go-plus.json MC(TC)|MCTC|TC mast cells http://purl.obolibrary.org/obo/CL_0000484 GO:0015538 biolink:MolecularActivity sialic acid:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in). Reactome:R-HSA-428585|RHEA:28987|Reactome:R-HSA-5624239 go-plus.json sialic acid permease activity|sialic acid:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015538 GO:0039501 biolink:BiologicalProcess suppression by virus of host type I interferon production Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. VZ:875 go-plus.json suppression by virus of host interferon type I production|suppression by virus of host type I IFN production|negative regulation by virus of host type I interferon production http://purl.obolibrary.org/obo/GO_0039501 CL:0000485 biolink:Cell mucosal type mast cell Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. go-plus.json MC(T)|MCT|T mast cells http://purl.obolibrary.org/obo/CL_0000485 CHEBI:134663 biolink:ChemicalSubstance N,N-dihydroxy-L-polyhomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134663 chebi_ph7_3 CHEBI:134668 biolink:ChemicalSubstance N-hydroxy-L-tetrahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134668 chebi_ph7_3 GO:0039506 biolink:BiologicalProcess modulation by virus of host molecular function The process in which a virus effects a change in the function of a host protein via a direct interaction. go-plus.json modification by virus of host protein function http://purl.obolibrary.org/obo/GO_0039506 CL:0000486 biolink:Cell garland cell A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae. go-plus.json garland nephrocyte http://purl.obolibrary.org/obo/CL_0000486 GO:0015531 biolink:MolecularActivity citrate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in). RHEA:32123 go-plus.json citrate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015531 GO:0015532 biolink:MolecularActivity alpha-ketoglutarate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in). go-plus.json alpha-ketoglutarate:hydrogen symporter activity|2-oxoglutarate:hydrogen symporter activity|2-oxoglutarate:proton symporter activity http://purl.obolibrary.org/obo/GO_0015532 GO:0039507 biolink:BiologicalProcess suppression by virus of host molecular function Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein. go-plus.json negative regulation by virus of host molecular function|down regulation by virus of host protein function|inhibition by virus of host protein function|inhibition of host protein function|negative regulation by virus of host protein function|down-regulation by virus of host protein function http://purl.obolibrary.org/obo/GO_0039507 CHEBI:134669 biolink:ChemicalSubstance N,N-dihydroxy-L-tetrahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134669 chebi_ph7_3 CL:0000487 biolink:Cell oenocyte A large secretory cell found in clusters underlying the epidermis of the abdominal segments of larval abdominal segments. go-plus.json http://purl.obolibrary.org/obo/CL_0000487 GO:0039504 biolink:BiologicalProcess suppression by virus of host adaptive immune response Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory). go-plus.json suppression by virus of host acquired immune response|inhibition of host adaptive immune response by virus|negative regulation by virus of host adaptive immunity|negative regulation by virus of host adaptive immune response http://purl.obolibrary.org/obo/GO_0039504 CL:0000488 biolink:Cell visible light photoreceptor cell A photoreceptor cell that detects visible light. go-plus.json http://purl.obolibrary.org/obo/CL_0000488 GO:0015533 biolink:MolecularActivity shikimate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in). go-plus.json shikimate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015533 CHEBI:134666 biolink:ChemicalSubstance N-hydroxy-L-trihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134666 chebi_ph7_3 GO:0039505 biolink:BiologicalProcess suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex. VZ:820 go-plus.json inhibition of host MHC class II molecule presentation by virus http://purl.obolibrary.org/obo/GO_0039505 GO:0015534 biolink:MolecularActivity obsolete proline/glycine/betaine:hydrogen/sodium symporter activity OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in). go-plus.json proline/glycine/betaine:hydrogen/sodium symporter activity|proline/glycine/betaine:proton/sodium symporter http://purl.obolibrary.org/obo/GO_0015534 CHEBI:134667 biolink:ChemicalSubstance N,N-dihydroxy-L-trihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134667 chebi_ph7_3 CHEBI:76244 biolink:ChemicalSubstance sapienic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76244 CHEBI:76241 biolink:ChemicalSubstance O-(S-acylpantetheine-4'-phosphoryl)serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_76241 GO:0015530 biolink:MolecularActivity shikimate transmembrane transporter activity Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids. go-plus.json http://purl.obolibrary.org/obo/GO_0015530 CHEBI:76242 biolink:ChemicalSubstance O-(S-acylpantetheine-4'-phosphoryl)serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76242 CHEBI:76247 biolink:ChemicalSubstance 4-hydroxy-2,5-dimethylfuran-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_76247 chebi_ph7_3 CHEBI:134660 biolink:ChemicalSubstance N-hydroxy-L-polyhomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134660 chebi_ph7_3 CHEBI:76248 biolink:ChemicalSubstance 4-hydroxy-2,5-dimethylfuran-3-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76248 chebi_ph7_3 CHEBI:134661 biolink:ChemicalSubstance 5(S),6(S)-epoxy-18(S)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134661 chebi_ph7_3 CHEBI:76245 biolink:ChemicalSubstance 4-hydroxy-5-methyl-2-methylenefuran-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_76245 chebi_ph7_3 CHEBI:76246 biolink:ChemicalSubstance 2-methyl-5-methylenefuran-3,4-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_76246 chebi_ph7_3 GO:1990086 biolink:BiologicalProcess lens fiber cell apoptotic process Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_1990086 GO:1990087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990087 GO:1990088 biolink:MolecularActivity [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]. RHEA:45208|EC:2.1.1.246 go-plus.json http://purl.obolibrary.org/obo/GO_1990088 GO:1990089 biolink:BiologicalProcess response to nerve growth factor A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus. go-plus.json response to nerve growth factor stimulus http://purl.obolibrary.org/obo/GO_1990089 GO:1990082 biolink:CellularComponent DnaA-L2 complex A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2. go-plus.json http://purl.obolibrary.org/obo/GO_1990082 GO:1990083 biolink:CellularComponent DnaA-Hda complex A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda. go-plus.json http://purl.obolibrary.org/obo/GO_1990083 GO:1990084 biolink:CellularComponent DnaA-Dps complex A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps. go-plus.json http://purl.obolibrary.org/obo/GO_1990084 GO:1990085 biolink:CellularComponent Hda-beta clamp complex A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda. go-plus.json Hda-DnaN complex|Hda-dpo3b complex http://purl.obolibrary.org/obo/GO_1990085 GO:1990080 biolink:MolecularActivity 2-phenylethylamine receptor activity Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity. go-plus.json beta-phenylethylamine receptor activity http://purl.obolibrary.org/obo/GO_1990080 GO:1990081 biolink:MolecularActivity trimethylamine receptor activity Combining with the biogenic amine trimethylamine to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_1990081 GO:0015546 biolink:MolecularActivity sulfathiazole transmembrane transporter activity Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group. go-plus.json sulphathiazole transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015546 GO:0015547 biolink:MolecularActivity nalidixic acid transmembrane transporter activity Enables the transfer of nalidixic acid from one side of a membrane to the other. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication. go-plus.json carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|nalidixic acid transporter activity http://purl.obolibrary.org/obo/GO_0015547 CL:0000494 biolink:Cell UV sensitive photoreceptor cell A photoreceptor cell that detects ultraviolet light. go-plus.json http://purl.obolibrary.org/obo/CL_0000494 CHEBI:134673 biolink:ChemicalSubstance N,N-dihydroxy-L-hexahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134673 chebi_ph7_3 GO:0015548 biolink:MolecularActivity organomercurial transmembrane transporter activity Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom. go-plus.json organomercurial transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015548 GO:0015549 biolink:MolecularActivity carbonyl cyanide m-chlorophenylhydrazone transmembrane transporter activity Enables the transfer of carbonyl cyanide m-chlorophenylhydrazone from one side of a membrane to the other. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes. go-plus.json carbonyl cyanide m-chlorophenylhydrazone transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|CCCP transporter activity http://purl.obolibrary.org/obo/GO_0015549 CHEBI:76250 biolink:ChemicalSubstance hydroxyisoflavans go-plus.json http://purl.obolibrary.org/obo/CHEBI_76250 GO:0015542 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015542 GO:0015543 biolink:MolecularActivity obsolete lactose/glucose efflux transporter activity OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out). go-plus.json lactose/glucose efflux transporter activity http://purl.obolibrary.org/obo/GO_0015543 CL:0000498 biolink:Cell inhibitory interneuron An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). go-plus.json http://purl.obolibrary.org/obo/CL_0000498 CHEBI:76251 biolink:ChemicalSubstance 1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76251 chebi_ph7_3 GO:0015544 biolink:MolecularActivity phenyl propionate uniporter activity Enables the transfer of phenyl propionate from one side of a membrane to the other. go-plus.json phenyl propionate permease activity http://purl.obolibrary.org/obo/GO_0015544 CL:0000499 biolink:Cell stromal cell A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. go-plus.json http://purl.obolibrary.org/obo/CL_0000499 GO:0015545 biolink:MolecularActivity bicyclomycin transmembrane transporter activity Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive. go-plus.json bicyclomycin transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015545 GO:0015540 biolink:MolecularActivity 3-hydroxyphenyl propionate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in). go-plus.json 3-hydroxyphenyl propionate porter activity|3-hydroxyphenyl propionate:hydrogen ion symporter activity http://purl.obolibrary.org/obo/GO_0015540 CHEBI:52267 biolink:ChemicalSubstance 7-hydroxyflavonol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52267 chebi_ph7_3 CHEBI:76253 biolink:ChemicalSubstance dTDP-4-dehydro-6-deoxy-alpha-D-gulose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76253 chebi_ph7_3 GO:0015541 biolink:MolecularActivity secondary active cyanate transmembrane transporter activity Enables the transfer of cyanate from one side of a membrane to the other. go-plus.json cyanate porter activity http://purl.obolibrary.org/obo/GO_0015541 CHEBI:52268 biolink:ChemicalSubstance flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]s go-plus.json http://purl.obolibrary.org/obo/CHEBI_52268 chebi_ph7_3 CHEBI:134671 biolink:ChemicalSubstance N,N-dihydroxy-L-pentahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134671 chebi_ph7_3 CHEBI:134672 biolink:ChemicalSubstance N-hydroxy-L-hexahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134672 chebi_ph7_3 CHEBI:134670 biolink:ChemicalSubstance N-hydroxy-L-pentahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_134670 chebi_ph7_3 CL:0000492 biolink:Cell CD4-positive helper T cell A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. go-plus.json CD4-positive helper T lymphocyte|CD4-positive T-helper cell|CD4-positive helper T-cell|CD4-positive helper T-lymphocyte http://purl.obolibrary.org/obo/CL_0000492 GO:1990097 biolink:CellularComponent SeqA-DNA complex A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle. go-plus.json SeqA-hemimethylated DNA complex|SeqA-dsDNA complex|SeqA-hemimethylation dsDNA complex http://purl.obolibrary.org/obo/GO_1990097 GO:1990098 biolink:CellularComponent core primosome complex A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication. go-plus.json core primosome http://purl.obolibrary.org/obo/GO_1990098 GO:1990099 biolink:CellularComponent pre-primosome complex Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component. go-plus.json prereplication complex|pre-replication complex|pre-primosome|preprimosome complex|preprimosome|pre-priming complex http://purl.obolibrary.org/obo/GO_1990099 GO:1990093 biolink:BiologicalProcess obsolete negative regulation of N-methyl-D-aspartate receptor clustering OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane. go-plus.json negative regulation of N-methyl-D-aspartate receptor clustering|negative regulation of NMDA receptor clustering http://purl.obolibrary.org/obo/GO_1990093 GO:1990094 biolink:BiologicalProcess obsolete positive regulation of N-methyl-D-aspartate receptor clustering OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane. go-plus.json positive regulation of NMDA receptor clustering|positive regulation of N-methyl-D-aspartate receptor clustering http://purl.obolibrary.org/obo/GO_1990094 CL:0000469 biolink:Cell ganglion mother cell A neural progenitor cell that is the daughter of a neuroblast (sensu arthopoda). The progeny of ganglion mother cells develop into neurons, glia and (occasionally) epithelial cells. go-plus.json http://purl.obolibrary.org/obo/CL_0000469 GO:1990095 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. go-plus.json http://purl.obolibrary.org/obo/GO_1990095 GO:1990096 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to superoxide Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. go-plus.json http://purl.obolibrary.org/obo/GO_1990096 GO:0015517 biolink:MolecularActivity galactose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in). go-plus.json lactose, galactose:hydrogen symporter activity|galactose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015517 GO:1990090 biolink:BiologicalProcess cellular response to nerve growth factor stimulus A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus. go-plus.json cellular response to NGF http://purl.obolibrary.org/obo/GO_1990090 GO:0015518 biolink:MolecularActivity arabinose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in). go-plus.json arabinose efflux transmembrane transporter activity|arabinose:hydrogen symporter activity|arabinose efflux permease activity http://purl.obolibrary.org/obo/GO_0015518 CHEBI:27295 biolink:ChemicalSubstance violaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27295 GO:0015519 biolink:MolecularActivity D-xylose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in). go-plus.json D-xylose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015519 GO:1990091 biolink:BiologicalProcess sodium-dependent self proteolysis The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. go-plus.json http://purl.obolibrary.org/obo/GO_1990091 GO:1990092 biolink:BiologicalProcess calcium-dependent self proteolysis The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. go-plus.json http://purl.obolibrary.org/obo/GO_1990092 GO:0015513 biolink:MolecularActivity high-affinity secondary active nitrite transmembrane transporter activity Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json nitrite uptake permease activity http://purl.obolibrary.org/obo/GO_0015513 CL:0000460 biolink:Cell glucocorticoid secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000460 GO:0015514 biolink:MolecularActivity nitrite efflux transmembrane transporter activity Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane. go-plus.json nitrite extrusion permease activity http://purl.obolibrary.org/obo/GO_0015514 GO:0015515 biolink:MolecularActivity citrate:succinate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015515 GO:0015516 biolink:MolecularActivity tartrate:succinate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015516 CHEBI:134641 biolink:ChemicalSubstance hydroperoxy(epoxy)icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134641 GO:0015510 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015510 GO:0015511 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015511 CL:0000467 biolink:Cell adrenocorticotropic hormone secreting cell A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. go-plus.json corticotropin secreting cell|corticotrophin hormone secreting cell|corticotropin hormone secreting cell|ACTH secreting cell|adrenocorticotrophic hormone secreting cell http://purl.obolibrary.org/obo/CL_0000467 GO:0015512 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015512 CHEBI:134645 biolink:ChemicalSubstance hydroperoxy(hydroxy)icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134645 CHEBI:76265 biolink:ChemicalSubstance 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76265 chebi_ph7_3 CHEBI:52254 biolink:ChemicalSubstance apatite go-plus.json http://purl.obolibrary.org/obo/CHEBI_52254 CHEBI:6198 biolink:ChemicalSubstance (S)-azetidine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_6198 CHEBI:52255 biolink:ChemicalSubstance hydroxylapatite go-plus.json http://purl.obolibrary.org/obo/CHEBI_52255 CHEBI:76264 biolink:ChemicalSubstance 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76264 chebi_ph7_3 NCBITaxon:5691 biolink:OrganismalEntity Trypanosoma brucei go-plus.json Trypanosoma brucei subgroup|Trypanosoma (Trypanozoon) brucei http://purl.obolibrary.org/obo/NCBITaxon_5691 NCBITaxon:5690 biolink:OrganismalEntity Trypanosoma go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5690 GO:0015528 biolink:MolecularActivity lactose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in). go-plus.json lactose, galactose:hydrogen symporter activity|lactose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015528 GO:0015529 biolink:MolecularActivity raffinose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in). go-plus.json raffinose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015529 GO:0015524 biolink:MolecularActivity obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out). go-plus.json L-arabinose/beta-D-thiogalactopyranoside:proton antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015524 GO:0015525 biolink:MolecularActivity obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:proton antiporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015525 CL:0000473 biolink:Cell defensive cell A cell whose primary function is to protect the organism. go-plus.json http://purl.obolibrary.org/obo/CL_0000473 GO:0015526 biolink:MolecularActivity hexose-phosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015526 CHEBI:134651 biolink:ChemicalSubstance hydroxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134651 CL:0000474 biolink:Cell pericardial nephrocyte An insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. go-plus.json pericardial cell http://purl.obolibrary.org/obo/CL_0000474 GO:0015527 biolink:MolecularActivity glycerol-phosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0015527 GO:0015520 biolink:MolecularActivity tetracycline:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out). go-plus.json tetracycline:hydrogen antiporter activity|tetracyclin:proton antiporter activity|tetracyclin:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015520 CHEBI:76272 biolink:ChemicalSubstance kaempferol 3-O-beta-D-xyloside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76272 chebi_ph7_3 CL:0000476 biolink:Cell thyrotroph A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. go-plus.json thyroid stimulating hormone secreting cell|beta-basophil|thyrotrope http://purl.obolibrary.org/obo/CL_0000476 GO:0015521 biolink:MolecularActivity obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in). go-plus.json bicyclomycin/sulphathiazole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:proton antiporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015521 CHEBI:76273 biolink:ChemicalSubstance dodecanedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76273 chebi_ph7_3 GO:0015522 biolink:MolecularActivity obsolete hydrophobic uncoupler:proton antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS. go-plus.json hydrophobic uncoupler:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0015522 CL:0000477 biolink:Cell ovarian follicle cell A somatic epithelial cell of the ovarian follicle/egg chamber. go-plus.json follicle cell http://purl.obolibrary.org/obo/CL_0000477 CHEBI:134655 biolink:ChemicalSubstance desmethylanhydrotetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_134655 CHEBI:76270 biolink:ChemicalSubstance cyclohex-1-ene-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76270 chebi_ph7_3 GO:0015523 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015523 CHEBI:76271 biolink:ChemicalSubstance cyclohexane-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76271 chebi_ph7_3 CHEBI:76276 biolink:ChemicalSubstance hexadecanedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76276 chebi_ph7_3 CHEBI:76275 biolink:ChemicalSubstance dTDP-alpha-D-fucofuranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76275 chebi_ph7_3 CHEBI:76278 biolink:ChemicalSubstance dehydrocoformycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76278 chebi_ph7_3 CHEBI:76279 biolink:ChemicalSubstance 2''-O-acetyl-ADP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_76279 GO:1990035 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990035 GO:1990036 biolink:BiologicalProcess calcium ion import into sarcoplasmic reticulum The directed movement of calcium ions into a sarcoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_1990036 GO:1990037 biolink:CellularComponent Lewy body core The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments. NIF_Subcellular:sao6587439252 go-plus.json http://purl.obolibrary.org/obo/GO_1990037 GO:1990038 biolink:CellularComponent Lewy body corona The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array. NIF_Subcellular:sao5764355747 go-plus.json halo http://purl.obolibrary.org/obo/GO_1990038 GO:1990031 biolink:CellularComponent pinceau fiber Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment. NIF_Subcellular:sao109906988 go-plus.json http://purl.obolibrary.org/obo/GO_1990031 GO:1990032 biolink:CellularComponent parallel fiber A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium. NIF_Subcellular:nlx_330 go-plus.json http://purl.obolibrary.org/obo/GO_1990032 GO:1990033 biolink:CellularComponent dendritic branch point The part of a dendritic tree where it branches, giving rise to a dendritic branch. NIF_Subcellular:sao1348591767 go-plus.json branch point of dendrite http://purl.obolibrary.org/obo/GO_1990033 GO:1990034 biolink:BiologicalProcess calcium ion export across plasma membrane The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json calcium ion efflux from cell|calcium ion export from cell http://purl.obolibrary.org/obo/GO_1990034 CHEBI:134628 biolink:ChemicalSubstance (1E,2S)-2-methylbutanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134628 chebi_ph7_3 CHEBI:134629 biolink:ChemicalSubstance (1Z,2S)-2-methylbutanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134629 chebi_ph7_3 CL:0000447 biolink:Cell carbohydrate secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000447 CHEBI:134626 biolink:ChemicalSubstance N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]acyl-beta-D-glucosyl-(1<->1)-sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134626 chebi_ph7_3 CL:0000448 biolink:Cell white fat cell Fat cells with light coloration and few mitochondria. They contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. go-plus.json white adipocyte|white adipose cell|white fat cell http://purl.obolibrary.org/obo/CL_0000448 CL:0000449 biolink:Cell brown fat cell A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. go-plus.json brown adipose cell|brown adipocyte http://purl.obolibrary.org/obo/CL_0000449 GO:1990030 biolink:CellularComponent pericellular basket Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name. NIF_Subcellular:sao413722576 go-plus.json peri cellular basket|peri-cellular basket http://purl.obolibrary.org/obo/GO_1990030 CHEBI:27273 biolink:ChemicalSubstance vanadic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27273 CHEBI:27275 biolink:ChemicalSubstance vanadium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_27275 CHEBI:134621 biolink:ChemicalSubstance N-[omega-(linoleoyloxy)]acyl-beta-D-glucosyl-(1<->1)-sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134621 chebi_ph7_3 CHEBI:76280 biolink:ChemicalSubstance dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76280 chebi_ph7_3 UBERON:0009877 biolink:AnatomicalEntity metapodium region Intermediate segment of the autopod, between the mesopodial region and and acropodial region. Examples: metacarpal region, metatarsal region go-plus.json cannon region|metapodium|metacarpus/metatarsus|metacarpus/metatarsus region|equine cannon region|metacarpal or metatarsal part of limb|metapodial segment http://purl.obolibrary.org/obo/UBERON_0009877 UBERON:0010855 biolink:AnatomicalEntity skin of forelimb wing A zone of skin that is part of a forelimb wing. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010855 UBERON:0010852 biolink:AnatomicalEntity fibula pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a fibula. go-plus.json fibulal pre-cartilage condensation|fibular pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010852 UBERON:0009878 biolink:AnatomicalEntity mesopodial skeleton The collection of all skeletal elements in a mesopodium. Examples: the tarsal skeleton, the carpal skeleton go-plus.json mesopodium skeleton|basipodium skeleton|skeletal parts of mesopodium|basipodium|mesopodium|carpal/tarsal skeleton|mesopodial skeleton http://purl.obolibrary.org/obo/UBERON_0009878 CL:0000440 biolink:Cell melanocyte stimulating hormone secreting cell A cell of the intermediate pituitary that produces melanocyte stimulating hormone. go-plus.json melanotroph|melanotrope http://purl.obolibrary.org/obo/CL_0000440 UBERON:0009879 biolink:AnatomicalEntity tarsal skeleton Subdivision of skeleton that consists of endochondral elements distal to the zeugopodial skeletal elements which constitute the proximal region of the posterior autopod skeleton[PHENOSCAPE:ad]. go-plus.json hind mesopodial skeleton|hind mesopodium|skeletal parts of hind mesopodium|hind mesopodium skeleton|set of tarsal bones|tarsalia|basipodium|mesopodium|tarsal bones set|tarsus|tarsal bones http://purl.obolibrary.org/obo/UBERON_0009879 CL:0000441 biolink:Cell follicle stem cell go-plus.json http://purl.obolibrary.org/obo/CL_0000441 CHEBI:134624 biolink:ChemicalSubstance N-[omega-(9R)-hydroperoxy-(10E,12Z)-octadecadienoyloxy]acyl-beta-D-glucosyl-(1<->1)-sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134624 chebi_ph7_3 CL:0000442 biolink:Cell follicular dendritic cell A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. go-plus.json http://purl.obolibrary.org/obo/CL_0000442 CHEBI:76283 biolink:ChemicalSubstance sebacate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76283 chebi_ph7_3 CL:0000443 biolink:Cell calcitonin secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000443 CHEBI:76281 biolink:ChemicalSubstance tetradecanedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76281 chebi_ph7_3 CHEBI:76282 biolink:ChemicalSubstance suberate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76282 chebi_ph7_3 UBERON:0009870 biolink:AnatomicalEntity zone of stomach A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland. go-plus.json gastric zone|section of stomach|region of stomach http://purl.obolibrary.org/obo/UBERON_0009870 UBERON:0009871 biolink:AnatomicalEntity nephrogenic zone Outer portion of the renal cortex. Site of formation of medullary and cortical elements. go-plus.json cortical nephrogenic zone|cortical nephrogenic niche|nephrogenic tissue http://purl.obolibrary.org/obo/UBERON_0009871 PR:000014271 biolink:Protein ubiquitin-40S ribosomal protein S27a A protein that is a translation product of the human RPS27A gene or a 1:1 ortholog thereof. go-plus.json UBCEP1|RPS27A|UBA80|40S ribosomal protein S27a http://purl.obolibrary.org/obo/PR_000014271 GO:1990039 biolink:CellularComponent hypolemmal cisterna Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer. NIF_Subcellular:sao1634374950 go-plus.json hypolemmal cisternae http://purl.obolibrary.org/obo/GO_1990039 CHEBI:76289 biolink:ChemicalSubstance dTDP-4-dehydro-6-deoxy-alpha-D-gulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_76289 GO:1990046 biolink:BiologicalProcess stress-induced mitochondrial fusion Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis. go-plus.json SIMH|stress-induced mitochondrial hyperfusion|mitochondrial fusion in response to stress http://purl.obolibrary.org/obo/GO_1990046 GO:1990047 biolink:CellularComponent spindle matrix A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_1990047 GO:1990048 biolink:BiologicalProcess anterograde neuronal dense core vesicle transport The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse. go-plus.json anterograde dense core granule trafficking|anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1990048 goslim_synapse GO:1990049 biolink:BiologicalProcess retrograde neuronal dense core vesicle transport The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body. go-plus.json retrograde dense core granule trafficking|retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_1990049 goslim_synapse GO:1990042 biolink:MolecularActivity glycerol dehydrogenase [NAD(P)+] activity Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced. go-plus.json glycerol dehydrogenase activity, NAD or NADP as acceptor http://purl.obolibrary.org/obo/GO_1990042 CHEBI:52225 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_52225 GO:1990043 biolink:MolecularActivity 5' deoxyribonuclease (pyrimidine dimer) activity Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990043 CHEBI:52226 biolink:ChemicalSubstance epi-cedrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52226 chebi_ph7_3 GO:1990044 biolink:BiologicalProcess protein localization to lipid droplet A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet. go-plus.json protein localisation to lipid particle|protein localisation to lipid droplet|protein localisation to adiposome|protein localisation to lipid body|protein localization to lipid particle|protein localization to lipid body|protein localization to adiposome http://purl.obolibrary.org/obo/GO_1990044 CHEBI:52228 biolink:ChemicalSubstance (3R)-all-trans-3-hydroxyretinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_52228 chebi_ph7_3 GO:1990045 biolink:BiologicalProcess sclerotium development The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions. go-plus.json http://purl.obolibrary.org/obo/GO_1990045 CL:0000457 biolink:Cell biogenic amine secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000457 CL:0000458 biolink:Cell serotonin secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). go-plus.json 5-Hydroxytryptamine secreting cell|5-HT secreting cell http://purl.obolibrary.org/obo/CL_0000458 CHEBI:27288 biolink:ChemicalSubstance vinca alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27288 CL:0000459 biolink:Cell noradrenergic cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. go-plus.json noradrenaline secreting cell|norepinephrin secreting cell|norepinephrine secreting cell http://purl.obolibrary.org/obo/CL_0000459 GO:1990040 biolink:CellularComponent sub-surface cisterna Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane. NIF_Subcellular:sao128470897 go-plus.json sub-surface cisternae http://purl.obolibrary.org/obo/GO_1990040 GO:1990041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990041 GO:0015506 biolink:MolecularActivity nucleoside:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in). go-plus.json nucleoside:hydrogen symporter activity|nucleoside:hydrogen ion symporter activity|nucleoside permease activity http://purl.obolibrary.org/obo/GO_0015506 UBERON:0010850 biolink:AnatomicalEntity tibia pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a tibia. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010850 CHEBI:27283 biolink:ChemicalSubstance very long-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27283 UBERON:0010851 biolink:AnatomicalEntity fibula cartilage element A cartilaginous condensation that has the potential to develop into a fibula. go-plus.json fibular cartilage condensation|fibulra cartilage condensation|fibulal cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010851 GO:0015507 biolink:MolecularActivity obsolete hydroxy/aromatic amino acid permease activity OBSOLETE. Permease for hydroxy and aromatic amino acids. go-plus.json hydroxy/aromatic amino acid permease activity http://purl.obolibrary.org/obo/GO_0015507 GO:0015508 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015508 GO:0015509 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015509 GO:0015502 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015502 CHEBI:134631 biolink:ChemicalSubstance L-polyhomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134631 chebi_ph7_3 UBERON:0010843 biolink:AnatomicalEntity clavicle cartilage element A cartilaginous condensation that has the potential to develop into a clavicle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010843 GO:0015503 biolink:MolecularActivity glutathione-regulated potassium exporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state. go-plus.json http://purl.obolibrary.org/obo/GO_0015503 CHEBI:134632 biolink:ChemicalSubstance L-dihomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134632 chebi_ph7_3 UBERON:0010844 biolink:AnatomicalEntity clavicle pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a clavicle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010844 CHEBI:76291 biolink:ChemicalSubstance nonanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76291 chebi_ph7_3 CL:0000451 biolink:Cell dendritic cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). go-plus.json interdigitating cell|veiled cell http://purl.obolibrary.org/obo/CL_0000451 GO:0015504 biolink:MolecularActivity cytosine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in). go-plus.json cytosine permease activity|cytosine:hydrogen ion symporter activity http://purl.obolibrary.org/obo/GO_0015504 GO:0015505 biolink:MolecularActivity uracil:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in). go-plus.json uracil permease activity http://purl.obolibrary.org/obo/GO_0015505 CHEBI:134630 biolink:ChemicalSubstance (2S)-2-methylbutanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_134630 chebi_ph7_3 CL:0000453 biolink:Cell Langerhans cell Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. go-plus.json LC|Langerhans' cell http://purl.obolibrary.org/obo/CL_0000453 CHEBI:134635 biolink:ChemicalSubstance L-pentahomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134635 chebi_ph7_3 CHEBI:76294 biolink:ChemicalSubstance kaempferol 3-O-beta-D-xyloside go-plus.json http://purl.obolibrary.org/obo/CHEBI_76294 CL:0000454 biolink:Cell epinephrine secreting cell A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. go-plus.json adrenaline secreting cell|epinephrin secreting cell http://purl.obolibrary.org/obo/CL_0000454 CHEBI:134636 biolink:ChemicalSubstance L-hexahomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134636 chebi_ph7_3 CHEBI:76295 biolink:ChemicalSubstance dTDP-alpha-D-fucofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_76295 GO:0015500 biolink:MolecularActivity obsolete threonine/serine:sodium symporter activity OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in). go-plus.json threonine/serine:sodium symporter activity http://purl.obolibrary.org/obo/GO_0015500 CHEBI:134633 biolink:ChemicalSubstance L-trihomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134633 chebi_ph7_3 CHEBI:76292 biolink:ChemicalSubstance trans-2-nonenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76292 chebi_ph7_3 GO:0015501 biolink:MolecularActivity glutamate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in). RHEA:29031 go-plus.json sodium/excitatory glutamate symporter activity|sodium/excitatory glutamate cotransporter activity http://purl.obolibrary.org/obo/GO_0015501 CHEBI:134634 biolink:ChemicalSubstance L-tetrahomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134634 chebi_ph7_3 CL:0000456 biolink:Cell mineralocorticoid secreting cell go-plus.json http://purl.obolibrary.org/obo/CL_0000456 CHEBI:76298 biolink:ChemicalSubstance 22-oxodocosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76298 chebi_ph7_3 CHEBI:52221 biolink:ChemicalSubstance isothiocyanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52221 CHEBI:52222 biolink:ChemicalSubstance (2R)-homocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52222 CHEBI:76299 biolink:ChemicalSubstance docosanedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76299 chebi_ph7_3 UBERON:0010849 biolink:AnatomicalEntity tibia cartilage element A cartilaginous condensation that has the potential to develop into a tibia. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010849 GO:1990057 biolink:BiologicalProcess obsolete cell cycle arrest in response to DNA damage stimulus OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism. go-plus.json cell cycle arrest in response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_1990057 GO:1990058 biolink:BiologicalProcess fruit replum development The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum. go-plus.json http://purl.obolibrary.org/obo/GO_1990058 GO:1990059 biolink:BiologicalProcess fruit valve development The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces. go-plus.json http://purl.obolibrary.org/obo/GO_1990059 GO:1990053 biolink:MolecularActivity DNA-5-methylcytosine glycosylase activity Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site. go-plus.json http://purl.obolibrary.org/obo/GO_1990053 CHEBI:27258 biolink:ChemicalSubstance uroporphyrinogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_27258 CHEBI:52214 biolink:ChemicalSubstance ligand go-plus.json http://purl.obolibrary.org/obo/CHEBI_52214 GO:1990054 biolink:BiologicalProcess response to temozolomide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990054 gocheck_do_not_manually_annotate CHEBI:52215 biolink:ChemicalSubstance photochemical role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52215 GO:1990055 biolink:MolecularActivity phenylacetaldehyde synthase activity Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2. RHEA:55532|EC:4.1.1.109 go-plus.json aromatic aldehyde synthase http://purl.obolibrary.org/obo/GO_1990055 CHEBI:52216 biolink:ChemicalSubstance photobiochemical role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52216 GO:1990056 biolink:MolecularActivity obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process. go-plus.json protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_1990056 CHEBI:52217 biolink:ChemicalSubstance pharmaceutical go-plus.json http://purl.obolibrary.org/obo/CHEBI_52217 CL:0000424 biolink:Cell excretory cell A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. go-plus.json http://purl.obolibrary.org/obo/CL_0000424 GO:1990050 biolink:MolecularActivity phosphatidic acid transfer activity Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3. go-plus.json intermembrane PA transfer activity|intermembrane phosphatidic acid transfer activity|phosphatidic acid carrier activity|phosphatidic acid transporter activity http://purl.obolibrary.org/obo/GO_1990050 CHEBI:134607 biolink:ChemicalSubstance beta-dihydromenaquinone-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134607 chebi_ph7_3 CHEBI:42896 biolink:ChemicalSubstance 1-thio-beta-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_42896 chebi_ph7_3 GO:1990051 biolink:BiologicalProcess activation of protein kinase C activity Any process that initiates the activity of the inactive enzyme protein kinase C. go-plus.json protein kinase C activation|PKC activation http://purl.obolibrary.org/obo/GO_1990051 GO:1990052 biolink:BiologicalProcess ER to chloroplast lipid transport The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast. go-plus.json endoplasmic reticulum to chloroplast lipid transport|ER to chloroplast lipid trafficking http://purl.obolibrary.org/obo/GO_1990052 CHEBI:27252 biolink:ChemicalSubstance uronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27252 UBERON:0009854 biolink:AnatomicalEntity digestive tract diverticulum Branch or outpocketing of the digestive tract. go-plus.json intestinal pouch|diverticulum of gut http://purl.obolibrary.org/obo/UBERON_0009854 UBERON:0009856 biolink:AnatomicalEntity sac go-plus.json pouch|diverticulum http://purl.obolibrary.org/obo/UBERON_0009856 CL:0000422 biolink:Cell mitogenic signaling cell A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. go-plus.json http://purl.obolibrary.org/obo/CL_0000422 CL:0000423 biolink:Cell tip cell go-plus.json http://purl.obolibrary.org/obo/CL_0000423 CHEBI:52210 biolink:ChemicalSubstance pharmacological role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52210 CHEBI:52211 biolink:ChemicalSubstance physiological role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52211 UBERON:0009850 biolink:AnatomicalEntity nematode larva A multicellular organism that existence_starts_and_ends_during a nematode larval stage. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009850 GO:1990068 biolink:BiologicalProcess seed dehydration The seed development process whose outcome is the drying of a maturing seed. go-plus.json http://purl.obolibrary.org/obo/GO_1990068 CHEBI:52208 biolink:ChemicalSubstance biophysical role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52208 GO:1990069 biolink:BiologicalProcess stomatal opening The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange. go-plus.json http://purl.obolibrary.org/obo/GO_1990069 CHEBI:52209 biolink:ChemicalSubstance aetiopathogenetic role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52209 GO:1990064 biolink:BiologicalProcess ground tissue pattern formation The regionalization process that gives rise to the patterning of the ground tissue. go-plus.json ground tissue patterning http://purl.obolibrary.org/obo/GO_1990064 UBERON:5002389 biolink:AnatomicalEntity manual digit plus metapodial segment A subdivision of the autopod consisting of manual digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. go-plus.json manual digit digitopodial subdivision|manual digit|manual digit ray|manual digit ( phalanges plus metapodial) plus soft tissue http://purl.obolibrary.org/obo/UBERON_5002389 GO:1990065 biolink:CellularComponent Dxr protein complex A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). go-plus.json 1-deoxy-D-xylulose 5-phosphate reductoisomerase complex http://purl.obolibrary.org/obo/GO_1990065 GO:1990066 biolink:BiologicalProcess energy quenching The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence. go-plus.json http://purl.obolibrary.org/obo/GO_1990066 GO:1990067 biolink:BiologicalProcess intrachromosomal DNA recombination The process of DNA recombination occurring within a single chromosome. go-plus.json intrastrand DNA recombination http://purl.obolibrary.org/obo/GO_1990067 CHEBI:52206 biolink:ChemicalSubstance biochemical role go-plus.json http://purl.obolibrary.org/obo/CHEBI_52206 GO:1990060 biolink:CellularComponent maltose transport complex Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK. go-plus.json maltose ABC transporter complex|maltose ATP-binding cassette transporter complex http://purl.obolibrary.org/obo/GO_1990060 CHEBI:134617 biolink:ChemicalSubstance epoxystearic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134617 GO:1990061 biolink:CellularComponent bacterial degradosome The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase. go-plus.json http://purl.obolibrary.org/obo/GO_1990061 CHEBI:27266 biolink:ChemicalSubstance valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27266 CHEBI:27267 biolink:ChemicalSubstance valine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_27267 GO:1990062 biolink:CellularComponent RPAP3/R2TP/prefoldin-like complex A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity. go-plus.json R2TP/prefoldin-like complex http://purl.obolibrary.org/obo/GO_1990062 CHEBI:134615 biolink:ChemicalSubstance hydroperoxyoctadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134615 CHEBI:134616 biolink:ChemicalSubstance 2-(glutathion-S-yl)-1,4-hydroquinone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134616 chebi_ph7_3 CL:0000438 biolink:Cell luteinizing hormone secreting cell A peptide hormone secreting cell pituitary that produces luteinizing hormone. go-plus.json http://purl.obolibrary.org/obo/CL_0000438 GO:1990063 biolink:CellularComponent Bam protein complex Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex. go-plus.json OMP complex http://purl.obolibrary.org/obo/GO_1990063 CL:0000439 biolink:Cell prolactin secreting cell A peptide hormone cell that secretes prolactin. go-plus.json http://purl.obolibrary.org/obo/CL_0000439 UBERON:0009843 biolink:AnatomicalEntity prostate epithelial cord A solid cord of prostate epithelium. go-plus.json epithelial cord of prostate|cord of prostate epithelium http://purl.obolibrary.org/obo/UBERON_0009843 UBERON:0009844 biolink:AnatomicalEntity urogenital sinus lumen An anatomical space that surrounded_by a primitive urogenital sinus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009844 CHEBI:134610 biolink:ChemicalSubstance N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134610 chebi_ph7_3 UBERON:0009845 biolink:AnatomicalEntity urogenital sinus mesenchyme Mesenchyme that surrounds primitive urogenital sinus. go-plus.json UGM http://purl.obolibrary.org/obo/UBERON_0009845 UBERON:0009846 biolink:AnatomicalEntity embryonic cloacal epithelium An epithelium that is part of a embryonic cloaca. go-plus.json cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0009846 CL:0000430 biolink:Cell xanthophore cell A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. go-plus.json xanthophore http://purl.obolibrary.org/obo/CL_0000430 CL:0000431 biolink:Cell iridophore A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. go-plus.json guanophore http://purl.obolibrary.org/obo/CL_0000431 UBERON:0009847 biolink:AnatomicalEntity prostate field A specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop. go-plus.json prostate primordium http://purl.obolibrary.org/obo/UBERON_0009847 CHEBI:134613 biolink:ChemicalSubstance hydroperoxyoctadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134613 UBERON:0009848 biolink:AnatomicalEntity zona limitans intrathalamica A narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. go-plus.json ZLI|MDO|ZLI organizer|mid-diencephalic organizer http://purl.obolibrary.org/obo/UBERON_0009848 UBERON:0009842 biolink:AnatomicalEntity glandular acinus The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. go-plus.json acini|acinus http://purl.obolibrary.org/obo/UBERON_0009842 CHEBI:66848 biolink:ChemicalSubstance phosphatidylcholine 32:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66848 chebi_ph7_3 CHEBI:66849 biolink:ChemicalSubstance phosphatidylcholine 32:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66849 chebi_ph7_3 GO:0039588 biolink:BiologicalProcess suppression by virus of host antigen processing and presentation Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex. VZ:815 go-plus.json inhibition of host proteasome antigen processing by virus http://purl.obolibrary.org/obo/GO_0039588 GO:0039589 biolink:BiologicalProcess obsolete suppression by virus of host TAP complex OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response. VZ:817 go-plus.json inhibition of host TAP by virus http://purl.obolibrary.org/obo/GO_0039589 GO:0039582 biolink:BiologicalProcess obsolete suppression by virus of host PKR activity by positive regulation of PKR nuclear localization OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha). go-plus.json suppression by virus of host PKR activity by nuclear sequestration of PKR|suppression by virus of host PKR activity by positive regulation of PKR localization to nucleus|suppression by virus of host PKR activity by sequestering of PKR in nucleus http://purl.obolibrary.org/obo/GO_0039582 GO:0039583 biolink:BiologicalProcess obsolete suppression by virus of host PKR activity by positive regulation of PKR catabolic process OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes. go-plus.json downregulation of PKR by degradation through proteosome|promotion by virus of proteosome-dependent PKR degradation http://purl.obolibrary.org/obo/GO_0039583 GO:0039580 biolink:BiologicalProcess suppression by virus of host PKR signaling Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha, inhibiting protein synthesis as an antiviral response. go-plus.json suppression by virus of host PKR activity|suppression by virus of host EIF2AK2 activity http://purl.obolibrary.org/obo/GO_0039580 GO:0039581 biolink:BiologicalProcess obsolete suppression by virus of host PKR activity via double-stranded RNA binding OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by binding to double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding. go-plus.json suppression by virus of host PKR activity by binding to dsRNA http://purl.obolibrary.org/obo/GO_0039581 GO:0039586 biolink:BiologicalProcess modulation by virus of host PP1 activity The process in which a virus effects a change in host protein phosphatase-1 (PP1) activity, a serine/threonine phosphatase. Different viruses modulate host PP1 activity to remove phosphates from various cellular substrates and downregulate the host's antiviral response. VZ:803 go-plus.json regulation by virus of host PP1 activity|modulation of host PP1 activity by virus http://purl.obolibrary.org/obo/GO_0039586 GO:0039587 biolink:BiologicalProcess suppression by virus of host tetherin activity Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects. VZ:665 go-plus.json suppression by virus of host BST-2 activity|inhibition of host BST2/Tetherin by virus http://purl.obolibrary.org/obo/GO_0039587 GO:0039584 biolink:BiologicalProcess suppression by virus of host protein kinase activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0039584 GO:0039585 biolink:BiologicalProcess PKR-mediated signaling A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR (also known as EIF2AK3), an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation. go-plus.json EIF2AK3 signal transduction|PKR signal transduction|PKR signaling pathway|signaling through PKR|EIF2AK3/PERK signaling http://purl.obolibrary.org/obo/GO_0039585 GO:1990002 biolink:MolecularActivity methylglyoxal reductase (NADPH-dependent, acetol producing) Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+. RHEA:27986 go-plus.json http://purl.obolibrary.org/obo/GO_1990002 GO:1990003 biolink:MolecularActivity inosine-diphosphatase activity Catalysis of the reaction: IDP + H2O = IMP + phosphate. Reactome:R-HSA-2509816|RHEA:35207|EC:3.6.1.64 go-plus.json inosine-diphosphatase activity|inosine diphosphatase activity|IDPase activity|IDP phosphatase activity http://purl.obolibrary.org/obo/GO_1990003 GO:1990004 biolink:MolecularActivity obsolete XDP phosphatase activity OBSOLETE. Catalysis of the reaction: XDP + H2O = XMP + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990004 GO:1990005 biolink:CellularComponent granular vesicle A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells. NIF_Subcellular:sao478230652 go-plus.json http://purl.obolibrary.org/obo/GO_1990005 GO:1990000 biolink:BiologicalProcess amyloid fibril formation The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. go-plus.json amyloid fibril assembly|amyloid structure formation|amyloid structure assembly http://purl.obolibrary.org/obo/GO_1990000 GO:1990001 biolink:BiologicalProcess inhibition of cysteine-type endopeptidase activity involved in apoptotic process Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process. go-plus.json http://purl.obolibrary.org/obo/GO_1990001 CHEBI:66850 biolink:ChemicalSubstance phosphatidylcholine 32:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66850 chebi_ph7_3 GO:0039579 biolink:BiologicalProcess suppression by virus of host ISG15 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 activity. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives. VZ:723 go-plus.json http://purl.obolibrary.org/obo/GO_0039579 GO:0039577 biolink:BiologicalProcess obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1. go-plus.json http://purl.obolibrary.org/obo/GO_0039577 GO:0039578 biolink:BiologicalProcess obsolete suppression by virus of host JAK1 activity via JAK1 binding OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive. go-plus.json http://purl.obolibrary.org/obo/GO_0039578 CHEBI:66855 biolink:ChemicalSubstance phosphatidylcholine 34:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66855 chebi_ph7_3 CHEBI:66856 biolink:ChemicalSubstance phosphatidylcholine 36:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66856 chebi_ph7_3 CHEBI:66857 biolink:ChemicalSubstance phosphatidylcholine 36:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66857 chebi_ph7_3 CHEBI:66858 biolink:ChemicalSubstance phosphatidylcholine 36:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66858 chebi_ph7_3 GO:0039571 biolink:BiologicalProcess obsolete suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation. go-plus.json inhibition by virus of tyrosine phosphorylation of STAT1 http://purl.obolibrary.org/obo/GO_0039571 GO:0039572 biolink:BiologicalProcess obsolete suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation. go-plus.json inhibition by virus of tyrosine phosphorylation of STAT2 http://purl.obolibrary.org/obo/GO_0039572 GO:0039570 biolink:BiologicalProcess obsolete suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes. go-plus.json cytoplasmic sequestering of STAT2|cytoplasmic sequestration of STAT2 http://purl.obolibrary.org/obo/GO_0039570 GO:0039575 biolink:BiologicalProcess obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2. go-plus.json inhibition by virus of host TYK2 activation|inhibition by virus of host TYK2 phosphorylation http://purl.obolibrary.org/obo/GO_0039575 GO:1990006 biolink:CellularComponent amorphous vesicle A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway. NIF_Subcellular:sao1531915298 go-plus.json http://purl.obolibrary.org/obo/GO_1990006 NCBITaxon:555406 biolink:OrganismalEntity Archamoebae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_555406 GO:0039576 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1). VZ:784 go-plus.json suppression by virus of host janus kinase 1 activity|suppression by virus of tyrosine phosphorylation of host STAT protein|suppression by virus of host JAK1 activity|viral inhibition of tyrosine phosphorylation of host STAT protein|inhibition of host JAK activity by virus|negative regulation by virus of tyrosine phosphorylation of host STAT protein|negative regulation by virus of host JAK http://purl.obolibrary.org/obo/GO_0039576 GO:1990007 biolink:CellularComponent membrane stack A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures. NIF_Subcellular:sao2114874506 go-plus.json http://purl.obolibrary.org/obo/GO_1990007 GO:1990008 biolink:CellularComponent neurosecretory vesicle A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus. NIF_Subcellular:sao2031592629 go-plus.json http://purl.obolibrary.org/obo/GO_1990008 GO:0039573 biolink:BiologicalProcess suppression by virus of host complement activation Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase. VZ:811 go-plus.json inhibition of host complement activation by virus|inhibition of host complement cascade by virus|inhibition of host complement factors by virus http://purl.obolibrary.org/obo/GO_0039573 GO:0039574 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits. go-plus.json suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity|suppression by virus of host TYK2 activity http://purl.obolibrary.org/obo/GO_0039574 GO:1990009 biolink:BiologicalProcess retinal cell apoptotic process Any apoptotic process in a retinal cell. go-plus.json induction of retinal programmed cell death http://purl.obolibrary.org/obo/GO_1990009 GO:1990013 biolink:CellularComponent presynaptic grid A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane. NIF_Subcellular:sao1730664005 go-plus.json pre-synaptic grid http://purl.obolibrary.org/obo/GO_1990013 GO:1990014 biolink:CellularComponent orthogonal array Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels). NIF_Subcellular:sao1747012216 go-plus.json orthogonal array of particles|square array|OAP http://purl.obolibrary.org/obo/GO_1990014 GO:1990015 biolink:CellularComponent ensheathing process A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma. NIF_Subcellular:sao1376748732 go-plus.json ensheathing process of Schwann cell http://purl.obolibrary.org/obo/GO_1990015 GO:1990016 biolink:CellularComponent neck portion of tanycyte Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. NIF_Subcellular:sao901230115 go-plus.json neck portion http://purl.obolibrary.org/obo/GO_1990016 GO:1990010 biolink:BiologicalProcess compound eye retinal cell apoptotic process Any apoptotic process in a compound eye retinal cell. go-plus.json http://purl.obolibrary.org/obo/GO_1990010 GO:1990011 biolink:CellularComponent laminated body Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus. NIF_Subcellular:sao506721981 go-plus.json laminated inclusion body http://purl.obolibrary.org/obo/GO_1990011 GO:1990012 biolink:CellularComponent complex laminated body A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint. NIF_Subcellular:nlx_151681 go-plus.json CLB http://purl.obolibrary.org/obo/GO_1990012 CHEBI:66862 biolink:ChemicalSubstance phosphatidylcholine 40:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_66862 chebi_ph7_3 GO:0039568 biolink:BiologicalProcess obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus. go-plus.json suppression by virus of host STAT1 activity by negative regulation of DNA binding|inhibition of DNA binding of STAT1 http://purl.obolibrary.org/obo/GO_0039568 GO:0039569 biolink:BiologicalProcess obsolete suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome. go-plus.json targeting STAT2 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT2 degradation|suppression by virus of host STAT2 activity by positive promotion of STAT2 proteasome-mediated degradation http://purl.obolibrary.org/obo/GO_0039569 GO:0039566 biolink:BiologicalProcess obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation. go-plus.json suppression by virus of host STAT1 activity by peptidyl-tyrosine dephosphorylation of STAT1|viral tyrosine phosphatase activity involved in suppression of host STAT1 http://purl.obolibrary.org/obo/GO_0039566 GO:0039567 biolink:BiologicalProcess obsolete suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes. go-plus.json suppression by virus of host STAT1 activity by cytoplasmic sequestering of STAT1|cytoplasmic sequestration of STAT1 http://purl.obolibrary.org/obo/GO_0039567 GO:0015597 biolink:MolecularActivity obsolete histidine/arginine/lysine/ornithine porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). go-plus.json histidine/arginine/lysine/ornithine porter activity http://purl.obolibrary.org/obo/GO_0015597 GO:0015598 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015598 CHEBI:66867 biolink:ChemicalSubstance trans,polycis-decaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66867 CHEBI:66868 biolink:ChemicalSubstance carboxyspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_66868 GO:0015599 biolink:MolecularActivity ATPase-coupled L-glutamine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in). EC:7.4.2.1|MetaCyc:ABC-12-RXN go-plus.json glutamine porter activity|ATPase-coupled glutamine transmembrane transporter activity|glutamine-importing ATPase activity http://purl.obolibrary.org/obo/GO_0015599 GO:0039560 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity Any process in which a virus stops, prevents, or reduces a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes. go-plus.json inhibition of host interferon regulatory factor-9 by virus|suppression by virus of host interferon regulatory factor 9 activity|inhibition of host IRF9 by virus|suppression by virus of host IRF9 activity http://purl.obolibrary.org/obo/GO_0039560 GO:0015593 biolink:MolecularActivity allose transmembrane transporter activity Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. go-plus.json http://purl.obolibrary.org/obo/GO_0015593 GO:0015594 biolink:MolecularActivity ABC-type putrescine transporter activity Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in). EC:7.6.2.16|RHEA:29995 go-plus.json putrescine porter activity|putrescine-importing ATPase activity|ATPase-coupled putrescine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015594 GO:0039561 biolink:BiologicalProcess obsolete suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism. go-plus.json suppression by virus of host IRF9 activity by nuclear localization of IRF9|suppression of interferon signaling by nuclear accumulation of IRF9 http://purl.obolibrary.org/obo/GO_0039561 GO:0015595 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015595 GO:0015596 biolink:MolecularActivity obsolete glycine betaine/proline porter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in). go-plus.json glycine betaine/proline porter activity http://purl.obolibrary.org/obo/GO_0015596 GO:1990017 biolink:CellularComponent somatic portion of tanycyte Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. NIF_Subcellular:sao401910342 go-plus.json somatic portion http://purl.obolibrary.org/obo/GO_1990017 GO:0039564 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2). go-plus.json inhibition of host STAT2 by virus|suppression by virus of host STAT2 activity|inhibition by virus of host STAT2 activity http://purl.obolibrary.org/obo/GO_0039564 GO:1990018 biolink:CellularComponent tail portion of tanycyte Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell. NIF_Subcellular:sao1749953771 go-plus.json tail portion http://purl.obolibrary.org/obo/GO_1990018 GO:0039565 biolink:BiologicalProcess obsolete suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome. go-plus.json targeting STAT1 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT1 degradation|suppression by virus of host STAT1 activity by positive promotion of STAT1 proteasome-mediated degradation http://purl.obolibrary.org/obo/GO_0039565 GO:0015590 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015590 GO:0039562 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade via inhibition of STAT activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes. go-plus.json inhibition by virus of host STAT activity|suppression by virus of host STAT activity|suppression by virus of host signal transducer and activator of transcription activity http://purl.obolibrary.org/obo/GO_0039562 GO:1990019 biolink:BiologicalProcess protein storage vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_1990019 GO:0015591 biolink:MolecularActivity D-ribose transmembrane transporter activity Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. go-plus.json http://purl.obolibrary.org/obo/GO_0015591 GO:0039563 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1). go-plus.json suppression by virus of host STAT1 activity|inhibition of host STAT1 by virus|inhibition by virus of host STAT1 activity http://purl.obolibrary.org/obo/GO_0039563 GO:0015592 biolink:MolecularActivity methylgalactoside transmembrane transporter activity Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group. go-plus.json galactose/glucose (methylgalactoside) porter activity http://purl.obolibrary.org/obo/GO_0015592 GO:1990024 biolink:CellularComponent C bouton Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons. NIF_Subcellular:nlx_subcell_100208 go-plus.json http://purl.obolibrary.org/obo/GO_1990024 GO:1990025 biolink:CellularComponent F bouton Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles. NIF_Subcellular:nlx_subcell_100206 go-plus.json http://purl.obolibrary.org/obo/GO_1990025 GO:1990026 biolink:CellularComponent hippocampal mossy fiber expansion Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites. NIF_Subcellular:nlx_subcell_1005002 go-plus.json mossy fiber expansion|dentate gyrus granule cell axonal bouton|dentate gyrus mossy fiber expansion http://purl.obolibrary.org/obo/GO_1990026 GO:1990027 biolink:CellularComponent S bouton Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles. NIF_Subcellular:nlx_subcell_100207 go-plus.json http://purl.obolibrary.org/obo/GO_1990027 GO:1990020 biolink:CellularComponent recurrent axon collateral Axon collateral that ramifies in the area of the soma of the cell of origin. NIF_Subcellular:sao1642494436 go-plus.json recurrent collateral http://purl.obolibrary.org/obo/GO_1990020 GO:1990021 biolink:CellularComponent Schaffer axon collateral Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1. NIF_Subcellular:nlx_subcell_20090511 go-plus.json Schaffer collateral http://purl.obolibrary.org/obo/GO_1990021 GO:1990022 biolink:BiologicalProcess obsolete RNA polymerase III complex import into nucleus OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus. go-plus.json DNA-directed RNA polymerase III complex localization to nucleus|RNA polymerase III complex localization to nucleus|DNA-directed RNA polymerase III complex import into nucleus|RNA polymerase III complex import into nucleus|RNA polymerase III complex localisation to nucleus http://purl.obolibrary.org/obo/GO_1990022 GO:1990023 biolink:CellularComponent mitotic spindle midzone The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner. go-plus.json http://purl.obolibrary.org/obo/GO_1990023 CHEBI:66873 biolink:ChemicalSubstance C4-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_66873 CHEBI:66874 biolink:ChemicalSubstance carnosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66874 UBERON:6000157 biolink:AnatomicalEntity embryonic head segment Any segment that is part of some embryonic head. go-plus.json http://purl.obolibrary.org/obo/UBERON_6000157 UBERON:6000154 biolink:AnatomicalEntity embryonic segment Any segment that is part of some embryo. go-plus.json http://purl.obolibrary.org/obo/UBERON_6000154 GO:0039557 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes. go-plus.json inhibition of host interferon regulatory factor-7 by virus|inhibition of host IRF7 by virus|suppression by virus of host IRF7 activity|suppression by virus of host interferon regulatory factor 7 activity http://purl.obolibrary.org/obo/GO_0039557 GO:0039558 biolink:BiologicalProcess obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity. go-plus.json suppression by virus of host interferon regulatory factor-7 activity by positive regulation of IRF7 sumoylation|promotion of IRF-7 SUMOylation http://purl.obolibrary.org/obo/GO_0039558 GO:0039555 biolink:BiologicalProcess obsolete suppression by virus of host MDA-5 activity via MDA-5 binding OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by binding to MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector. go-plus.json suppression by virus of host MDA5 activity by MDA-5 binding http://purl.obolibrary.org/obo/GO_0039555 GO:0039556 biolink:MolecularActivity MDA-5 binding Binding to MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA. go-plus.json MDA5 binding http://purl.obolibrary.org/obo/GO_0039556 CHEBI:66878 biolink:ChemicalSubstance pseudooxynicotinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66878 chebi_ph7_3 GO:0039559 biolink:BiologicalProcess obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome. go-plus.json promotion by virus of proteosome-dependent IRF7 degradation http://purl.obolibrary.org/obo/GO_0039559 CHEBI:66879 biolink:ChemicalSubstance 4-oxo-4-(pyridin-3-yl)butanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_66879 chebi_ph7_3 GO:0039550 biolink:BiologicalProcess obsolete suppression by virus of host IRF3 activity by inhibition of DNA binding OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites. go-plus.json inhibition by virus of host IRF3-DNA binding http://purl.obolibrary.org/obo/GO_0039550 GO:0039553 biolink:BiologicalProcess suppression by virus of host chemokine activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host chemokine activity. VZ:813 go-plus.json downregulation by virus of host chemokine activity|inhibition by virus of host chemokine activity|down-regulation by virus of host chemokine activity|negative regulation by virus of host chemokine activity|inhibition of host chemokines by virus http://purl.obolibrary.org/obo/GO_0039553 GO:1990028 biolink:MolecularActivity intermediate voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded. go-plus.json R-type calcium channel http://purl.obolibrary.org/obo/GO_1990028 GO:0039554 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. go-plus.json inhibition by virus of host MDA-5 signaling|suppression by virus of host IFIH1 signaling pathway|suppression by virus of host MDA-5 activity|suppression by virus of host MDA-5 signaling pathway|suppression by virus of host MDA-5 signalling pathway|inhibition of host IFIH1/MDA5 by virus|Inhibition of host MDA5 by virus http://purl.obolibrary.org/obo/GO_0039554 GO:1990029 biolink:BiologicalProcess vasomotion The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm. go-plus.json http://purl.obolibrary.org/obo/GO_1990029 GO:0039551 biolink:BiologicalProcess obsolete suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome. go-plus.json promotion by virus of proteosome-dependent IRF3 degradation http://purl.obolibrary.org/obo/GO_0039551 GO:0039552 biolink:MolecularActivity RIG-I binding Binding to RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA. go-plus.json DDX58 binding|DDX58/RIG-I binding http://purl.obolibrary.org/obo/GO_0039552 CHEBI:76206 biolink:ChemicalSubstance xenobiotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_76206 CHEBI:66884 biolink:ChemicalSubstance N-alkylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_66884 chebi_ph7_3 CHEBI:66887 biolink:ChemicalSubstance (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66887 chebi_ph7_3 OBA:VT0010454 biolink:OntologyClass organism trait The quality when measured in multicellular organism. go-plus.json http://purl.obolibrary.org/obo/OBA_VT0010454 CHEBI:66881 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-ribofuranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66881 chebi_ph7_3 CHEBI:66882 biolink:ChemicalSubstance 4-(methylamino)butyric acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_66882 chebi_ph7_3 GO:0015579 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015579 GO:0039546 biolink:BiologicalProcess obsolete suppression by virus of host MAVS activity by MAVS proteolysis OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling. go-plus.json viral protease cleavage of MAVS http://purl.obolibrary.org/obo/GO_0039546 GO:0039547 biolink:BiologicalProcess suppression by virus of host TRAF activity Any process in which a virus stops, prevents, or reduces the activity of a host TRAF (tumor necrosis factor receptor-associated factor) protein. TRAFs are intracellular signal transducers that lie downstream of receptors including RIG-I, MDA-5 and Toll-like receptors (TLR) and transfer the signal to other intracellular signaling components. go-plus.json inhibition of host TRAFs by virus http://purl.obolibrary.org/obo/GO_0039547 GO:0039544 biolink:BiologicalProcess obsolete suppression by virus of host RIG-I activity by RIG-I proteolysis OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction. go-plus.json cleavage of RIG-I by viral proteinase|inhibition by virus of host RIG-I activity by RIG-I proteolysis http://purl.obolibrary.org/obo/GO_0039544 GO:0039545 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses. go-plus.json suppression by virus of host mitochondrial antiviral-signaling protein|inhibition of host MAVS by virus|suppression by virus of host MAVS activity http://purl.obolibrary.org/obo/GO_0039545 GO:0015575 biolink:MolecularActivity mannitol transmembrane transporter activity Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group. go-plus.json mannitol permease activity http://purl.obolibrary.org/obo/GO_0015575 CHEBI:66888 biolink:ChemicalSubstance (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_66888 chebi_ph7_3 GO:0015576 biolink:MolecularActivity sorbitol transmembrane transporter activity Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose. go-plus.json glucitol permease activity|sorbitol permease activity|glucitol transporter activity http://purl.obolibrary.org/obo/GO_0015576 GO:0015577 biolink:MolecularActivity galactitol transmembrane transporter activity Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. RHEA:33143 go-plus.json galactitol permease activity http://purl.obolibrary.org/obo/GO_0015577 GO:0039548 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes. go-plus.json inhibition of IRF3-dependent antiviral response|inhibition of host IRF3 by virus|suppression by virus of host interferon regulatory factor 3|suppression by virus of host IRF3 activity http://purl.obolibrary.org/obo/GO_0039548 GO:0015578 biolink:MolecularActivity mannose transmembrane transporter activity Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. go-plus.json mannose permease activity http://purl.obolibrary.org/obo/GO_0015578 GO:0039549 biolink:BiologicalProcess obsolete suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes. go-plus.json inhibition of phosphorylation-induced activation of host IRF3|inhibition of virus-induced IRF-3 phosphorylation http://purl.obolibrary.org/obo/GO_0039549 GO:0015571 biolink:MolecularActivity N-acetylgalactosamine transmembrane transporter activity Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine. go-plus.json N-acetylgalactosamine permease activity http://purl.obolibrary.org/obo/GO_0015571 GO:0015572 biolink:MolecularActivity N-acetylglucosamine transmembrane transporter activity Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. go-plus.json N-Acetyl-D-glucosamine permease|N-acetylglucosamine permease activity|D-GlcNAc transmembrane transporter activity|N-acetylchitosamine transmembrane transporter activity|N-acetyl-D-glucosamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015572 GO:0015573 biolink:MolecularActivity beta-glucoside transmembrane transporter activity Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration. go-plus.json beta-glucoside permease activity http://purl.obolibrary.org/obo/GO_0015573 GO:0015574 biolink:MolecularActivity trehalose transmembrane transporter activity Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens. go-plus.json trehalose permease activity http://purl.obolibrary.org/obo/GO_0015574 GO:0039542 biolink:BiologicalProcess obsolete suppression by virus of host RIG-I K63-linked ubiquitination OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity. go-plus.json inhibition by virus of host DDX58 K63-linked ubiquitination|inhibition by virus of host RIG-I activity by inhibition of RIG-I ubiquitination|inhibition by virus of TRIM25-mediated ubiquitination of host RIG-I http://purl.obolibrary.org/obo/GO_0039542 GO:0039543 biolink:BiologicalProcess obsolete suppression by virus of host RIG-I activity by viral RNA 5' processing OBSOLETE. The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition. go-plus.json suppression by virus of host RIG-I activity by inhibition of RNA binding http://purl.obolibrary.org/obo/GO_0039543 GO:0039540 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. go-plus.json inhibition by virus of host DDX58 activity|suppression by virus of host RIG-I signaling pathway|suppression by virus of host RIG-I activity|suppression by virus of host DDX58 signaling pathway|inhibition by virus of host RIG-I|suppression by virus of host RIG-I signalling pathway|inhibition of host DDX58/RIG-I by virus|inhibition by virus of host RIG-I signaling http://purl.obolibrary.org/obo/GO_0039540 GO:0039541 biolink:BiologicalProcess obsolete suppression by virus of host RIG-I via RIG-I binding OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by binding to RIG-I itself. go-plus.json inhibition by virus of host DDX58:MAVS binding http://purl.obolibrary.org/obo/GO_0039541 GO:0015570 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015570 CHEBI:76202 biolink:ChemicalSubstance riboflavin cyclic 4',5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76202 chebi_ph7_3 CHEBI:66896 biolink:ChemicalSubstance (+)-5-oxo-1,2-campholide go-plus.json http://purl.obolibrary.org/obo/CHEBI_66896 chebi_ph7_3 CHEBI:66898 biolink:ChemicalSubstance (3R)-11-cis-3-hydroxyretinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_66898 chebi_ph7_3 CHEBI:66893 biolink:ChemicalSubstance 4-(6-hydroxypyridin-3-yl)-4-oxobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_66893 chebi_ph7_3 UBERON:6000137 biolink:AnatomicalEntity embryonic tagma Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052). go-plus.json http://purl.obolibrary.org/obo/UBERON_6000137 GO:0039535 biolink:BiologicalProcess regulation of RIG-I signaling pathway Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. go-plus.json regulation of RIG-I signalling pathway|regulation of retinoic acid inducible gene I signaling pathway|regulation of DDX58 signaling pathway http://purl.obolibrary.org/obo/GO_0039535 GO:0039536 biolink:BiologicalProcess negative regulation of RIG-I signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. go-plus.json negative regulation of RIG-I signalling pathway|negative regulation of retinoic acid inducible gene I signaling pathway|negative regulation of DDX58 signaling pathway http://purl.obolibrary.org/obo/GO_0039536 GO:0039533 biolink:BiologicalProcess regulation of MDA-5 signaling pathway Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. go-plus.json regulation of IFIH1 signaling pathway|regulation of MDA5 signaling pathway|regulation of MDA-5 signalling pathway|regulation of melanoma differentiation-associated gene 5 signaling pathway http://purl.obolibrary.org/obo/GO_0039533 GO:0039534 biolink:BiologicalProcess negative regulation of MDA-5 signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. go-plus.json negative regulation of MDA-5 signalling pathway|negative regulation of melanoma differentiation-associated gene 5 signaling pathway|negative regulation of IFIH1 signaling pathway|negative regulation of MDA5 signaling pathway http://purl.obolibrary.org/obo/GO_0039534 GO:0039539 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0039539 GO:0015586 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015586 GO:0015587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015587 GO:0039537 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. This is a mechanism by which the virus evades the host innate immune response. go-plus.json suppression by virus of host RIG-like helicase signaling pathway|suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signalling pathway|suppression by virus of host cytoplasmic pattern recognition receptor signaling pathway in response to virus|suppression by virus of host RIG-I/MDA5 signaling pathway|suppression by virus of host RIG-like receptor signaling pathway|suppression by virus of host RIG-I-like receptor (RLR) signaling pathway|suppression by virus of host RLR signaling pathway http://purl.obolibrary.org/obo/GO_0039537 GO:0015588 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015588 GO:0039538 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0039538 GO:0015589 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015589 GO:0015582 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015582 GO:0015583 biolink:MolecularActivity obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose. go-plus.json beta-glucoside [arbutin-salicin-cellobiose] permease activity http://purl.obolibrary.org/obo/GO_0015583 GO:0015584 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015584 GO:0015585 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015585 GO:0039531 biolink:BiologicalProcess regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. go-plus.json regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway|regulation of MAV signaling http://purl.obolibrary.org/obo/GO_0039531 GO:0039532 biolink:BiologicalProcess negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. go-plus.json negative regulation of MAVS signaling|negative regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway|negative regulation of cytoplasmic pattern recognition receptor signaling pathway in response to virus http://purl.obolibrary.org/obo/GO_0039532 CHEBI:76215 biolink:ChemicalSubstance dotriacontanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76215 GO:0015580 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015580 GO:0039530 biolink:BiologicalProcess MDA-5 signaling pathway Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. go-plus.json MDA-5 signalling pathway|melanoma differentiation-associated gene 5 signaling pathway|IFIH1 signaling pathway|MDA5 signaling pathway http://purl.obolibrary.org/obo/GO_0039530 GO:0015581 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015581 CHEBI:144019 biolink:ChemicalSubstance 5'-end phospho-(purine-ribonucleoside)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_144019 chebi_ph7_3 GO:0039524 biolink:BiologicalProcess suppression by virus of host mRNA processing Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. VZ:903 go-plus.json inhibition of host pre-mRNA processing by virus|inhibition of host mRNA processing by virus|negative regulation by virus of host mRNA processing|inhibition by virus of host mRNA processing http://purl.obolibrary.org/obo/GO_0039524 GO:0015557 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015557 CHEBI:52290 biolink:ChemicalSubstance mitogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_52290 GO:0039525 biolink:BiologicalProcess modulation by virus of host chromatin organization Any process in which a virus effects a change in the organization of chromatin in the host. go-plus.json modulation of host chromatin by virus|modulation of host chromatin structure by virus|regulation by virus of host chromatin organization|modulation by virus of host chromatin organisation http://purl.obolibrary.org/obo/GO_0039525 GO:0015558 biolink:MolecularActivity secondary active p-aminobenzoyl-glutamate transmembrane transporter activity Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid. go-plus.json p-aminobenzoyl-glutamate transporter activity|p-aminobenzoyl-glutamate uptake permease activity|p-aminobenzoyl-glutamate uptake transmembrane transporter activity|p-aminobenzoyl-glutamate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015558 GO:0039522 biolink:BiologicalProcess suppression by virus of host mRNA export from nucleus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism. VZ:902 go-plus.json inhibition of host mRNA nuclear export by virus|negative regulation by virus of host mRNA nuclear export|inhibition by virus of host mRNA nuclear export|suppression of host mRNA nuclear export by virus http://purl.obolibrary.org/obo/GO_0039522 GO:0015559 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015559 CHEBI:134684 biolink:ChemicalSubstance (E)-8-(methylsulfanyl)octanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134684 chebi_ph7_3 GO:0039523 biolink:BiologicalProcess suppression by virus of host RNA polymerase II activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host RNA polymerase II activity. VZ:905 go-plus.json inhibition of host RNA polymerase II activity by virus|negative regulation by virus of host RNA polymerase II activity|inhibition of host RNA polymerase II by virus http://purl.obolibrary.org/obo/GO_0039523 CHEBI:134685 biolink:ChemicalSubstance (E)-9-(methylsulfanyl)nonanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134685 chebi_ph7_3 GO:0039528 biolink:BiologicalProcess cytoplasmic pattern recognition receptor signaling pathway in response to virus Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. go-plus.json virus-induced cytoplasmic pattern recognition receptor signaling pathway|RIG-like helicase signaling pathway|cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway|RIG-I/MDA5 signaling pathway|RIG-I-like receptor (RLR) signaling pathway|cytoplasmic pattern recognition receptor signalling pathway in response to virus|RIG-like receptor signaling pathway|RLH signaling pathway|RLR signaling pathway http://purl.obolibrary.org/obo/GO_0039528 GO:0015553 biolink:MolecularActivity xanthosine transmembrane transporter activity Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015553 GO:0039529 biolink:BiologicalProcess RIG-I signaling pathway Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. go-plus.json RIG-I signalling pathway|retinoic acid inducible gene I signaling pathway|DDX58 signaling pathway http://purl.obolibrary.org/obo/GO_0039529 GO:0015554 biolink:MolecularActivity tartrate transmembrane transporter activity Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0015554 GO:0039526 biolink:BiologicalProcess modulation by virus of host apoptotic process Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells. VZ:1581 go-plus.json modulation of host cell apoptosis by virus|modulation by virus of host apoptosis|regulation by virus of host apoptosis http://purl.obolibrary.org/obo/GO_0039526 GO:0015555 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015555 GO:0015556 biolink:MolecularActivity C4-dicarboxylate transmembrane transporter activity Enables the transfer of C4-dicarboxylate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015556 GO:0039527 biolink:BiologicalProcess suppression by virus of host TRAF-mediated signal transduction Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of TRAF-mediated signal transduction in the host. go-plus.json suppression by virus of host tumor necrosis factor receptor-associated factor signaling|negative regulation by virus of host TRAF-mediated signal transduction|inhibition of host TRAF-mediated signal transduction by virus http://purl.obolibrary.org/obo/GO_0039527 GO:0015550 biolink:MolecularActivity galacturonate transmembrane transporter activity Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0015550 CHEBI:76222 biolink:ChemicalSubstance 1-O-acyl-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76222 chebi_ph7_3 GO:0015551 biolink:MolecularActivity 3-hydroxyphenyl propanoate transmembrane transporter activity Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other. go-plus.json 3-hydroxyphenyl propionate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015551 CHEBI:76220 biolink:ChemicalSubstance omega-hydroxytriacontanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76220 GO:0015552 biolink:MolecularActivity propionate transmembrane transporter activity Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH. go-plus.json http://purl.obolibrary.org/obo/GO_0015552 GO:0039520 biolink:BiologicalProcess induction by virus of host autophagy Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host. VZ:846 go-plus.json positive regulation by virus of host autophagy|activation of host autophagy by virus http://purl.obolibrary.org/obo/GO_0039520 CHEBI:134682 biolink:ChemicalSubstance (E)-5-(methylsulfanyl)pentanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134682 chebi_ph7_3 CHEBI:76225 biolink:ChemicalSubstance 1-alkyl-3-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76225 chebi_ph7_3 CHEBI:134683 biolink:ChemicalSubstance (E)-7-(methylsulfanyl)heptanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134683 chebi_ph7_3 GO:0039521 biolink:BiologicalProcess suppression by virus of host autophagy Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host. VZ:845 go-plus.json negative regulation by virus of host autophagy|inhibition by virus of host autophagy|inhibition of host autophagy by virus http://purl.obolibrary.org/obo/GO_0039521 CHEBI:76226 biolink:ChemicalSubstance N-hexanoyldihydroceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_76226 chebi_ph7_3 CHEBI:134680 biolink:ChemicalSubstance omega-(methylsulfanyl)-(E)-alkanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134680 chebi_ph7_3 CHEBI:76224 biolink:ChemicalSubstance aromatic ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_76224 CHEBI:134681 biolink:ChemicalSubstance (E)-6-(methylsulfanyl)hexanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_134681 chebi_ph7_3 CHEBI:76238 biolink:ChemicalSubstance protopanaxadiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76238 chebi_ph7_3 UBERON:6000119 biolink:AnatomicalEntity insect anterior ectoderm The region of the ectoderm anterior to the cephalic furrow. go-plus.json http://purl.obolibrary.org/obo/UBERON_6000119 GO:0039519 biolink:BiologicalProcess modulation by virus of host autophagy Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host. go-plus.json regulation by virus of host autophagy http://purl.obolibrary.org/obo/GO_0039519 GO:0015568 biolink:MolecularActivity L-idonate transmembrane transporter activity Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. go-plus.json L-idonate/D-gluconate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015568 GO:0039513 biolink:BiologicalProcess suppression by virus of host catalytic activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. go-plus.json negative regulation by virus of host catalytic activity|downregulation by virus of host catalytic activity|down-regulation by virus of host enzyme activity|inhibition by virus of host catalytic activity http://purl.obolibrary.org/obo/GO_0039513 GO:0015569 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015569 GO:0039514 biolink:BiologicalProcess suppression by virus of host JAK-STAT cascade Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signal cascade in the host organism. go-plus.json downregulation by virus of host JAK-STAT cascade|inhibition by virus of host JAK-STAT cascade|negative regulation by virus of host JAK-STAT cascade|down-regulation by virus of host JAK-STAT cascade http://purl.obolibrary.org/obo/GO_0039514 CHEBI:52280 biolink:ChemicalSubstance isopimara-7,15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_52280 chebi_ph7_3 GO:0039511 biolink:BiologicalProcess suppression by virus of host interferon receptor activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host interferon receptor. VZ:843 go-plus.json down-regulation by virus of host interferon receptor activity|negative regulation by virus of host interferon receptor activity|inhibition of host interferon receptors by virus|downregulation by virus of host interferon receptor activity|inhibition by virus of host interferon receptor activity http://purl.obolibrary.org/obo/GO_0039511 GO:0039512 biolink:BiologicalProcess suppression by virus of host protein tyrosine kinase activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein tyrosine kinase activity. go-plus.json negative regulation by virus of host protein tyrosine kinase activity|down-regulation by virus of host protein tyrosine kinase activity|downregulation by virus of host protein tyrosine kinase activity|inhibition by virus of host protein tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0039512 GO:0015564 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015564 GO:0039517 biolink:BiologicalProcess modulation by virus of host protein serine/threonine phosphatase activity The process in which a virus effects a change in host protein serine/threonine phosphatase activity. go-plus.json modulation by virus of protein serine/threonine phosphatase activity in host|regulation by virus of host protein serine/threonine phosphatase activity http://purl.obolibrary.org/obo/GO_0039517 GO:0039518 biolink:BiologicalProcess suppression by virus of host cytokine activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host cytokine activity. go-plus.json downregulation by virus of host cytokine activity|negative regulation by virus of host cytokine activity|down-regulation by virus of host cytokine activity|inhibition by virus of host cytokine activity http://purl.obolibrary.org/obo/GO_0039518 GO:0015565 biolink:MolecularActivity threonine efflux transmembrane transporter activity Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane. go-plus.json threonine efflux permease activity|threonine export transporter activity|threonine export protein http://purl.obolibrary.org/obo/GO_0015565 GO:0015566 biolink:MolecularActivity acriflavine transmembrane transporter activity Enables the directed movement of acriflavin from one side of a membrane to the other. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication. go-plus.json acriflavin resistant pump activity|acriflavine transporter activity|acriflavin transporter activity http://purl.obolibrary.org/obo/GO_0015566 GO:0039515 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0039515 GO:0015567 biolink:MolecularActivity alkane transmembrane transporter activity Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0015567 GO:0039516 biolink:BiologicalProcess modulation by virus of host catalytic activity The process in which a virus effects a change in host enzyme activity. go-plus.json modulation of catalytic activity of host by virus|regulation by virus of host catalytic activity|regulation of host catalytic activity by virus http://purl.obolibrary.org/obo/GO_0039516 GO:0015560 biolink:MolecularActivity obsolete L-idonate/D-gluconate:hydrogen symporter activity OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in). go-plus.json L-idonate/D-gluconate:hydrogen symporter activity|L-idonate/D-gluconate:proton symporter http://purl.obolibrary.org/obo/GO_0015560 GO:0015561 biolink:MolecularActivity rhamnose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in). TC:2.A.7.6 go-plus.json rhamnose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015561 CHEBI:76233 biolink:ChemicalSubstance 2-linoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76233 CHEBI:52288 biolink:ChemicalSubstance 1-octadec-9-enoylglycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52288 GO:0015562 biolink:MolecularActivity efflux transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. go-plus.json monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity|efflux permease activity http://purl.obolibrary.org/obo/GO_0015562 CHEBI:52289 biolink:ChemicalSubstance wortmannin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52289 chebi_ph7_3 GO:0015563 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015563 CHEBI:76231 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76231 CHEBI:52283 biolink:ChemicalSubstance 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52283 CHEBI:76236 biolink:ChemicalSubstance (R)-2-hydroperoxy-alpha-linolenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76236 GO:0039510 biolink:BiologicalProcess obsolete suppression by virus of host ATP-dependent RNA helicase activity OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity. go-plus.json negative regulation by virus of host ATP-dependent RNA helicase activity|down-regulation by virus of host ATP-dependent RNA helicase activity|inhibition by virus of host ATP-dependent RNA helicase activity|downregulation by virus of host ATP-dependent RNA helicase activity http://purl.obolibrary.org/obo/GO_0039510 CHEBI:52285 biolink:ChemicalSubstance 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52285 CHEBI:76234 biolink:ChemicalSubstance (R)-2-hydroxy-alpha-linolenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76234 CHEBI:76235 biolink:ChemicalSubstance (8Z,11Z,14Z)-heptadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76235 GO:0098046 biolink:CellularComponent type V protein secretion system complex A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc). go-plus.json T5SS complex|autotransporter system complex http://purl.obolibrary.org/obo/GO_0098046 GO:0098045 biolink:BiologicalProcess virus baseplate assembly The aggregation, arrangement and bonding together of a set of components to form a virus baseplate. go-plus.json http://purl.obolibrary.org/obo/GO_0098045 CHEBI:17828 biolink:ChemicalSubstance 2,3-dihydroxyindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_17828 chebi_ph7_3 CHEBI:17826 biolink:ChemicalSubstance methylarsonous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17826 chebi_ph7_3 CHEBI:17827 biolink:ChemicalSubstance methyl-CoM go-plus.json http://purl.obolibrary.org/obo/CHEBI_17827 CHEBI:17824 biolink:ChemicalSubstance propan-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17824 chebi_ph7_3 CHEBI:17825 biolink:ChemicalSubstance 7-methylguanosine 5'-phosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17825 CHEBI:17822 biolink:ChemicalSubstance serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17822 CHEBI:17823 biolink:ChemicalSubstance calcitriol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17823 chebi_ph7_3 CHEBI:17820 biolink:ChemicalSubstance 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17820 CHEBI:17821 biolink:ChemicalSubstance thymine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17821 chebi_ph7_3 GO:1990400 biolink:MolecularActivity mitochondrial ribosomal large subunit rRNA binding Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA). go-plus.json 21S rRNA binding|mitochondrial LSU rRNA binding http://purl.obolibrary.org/obo/GO_1990400 GO:1990401 biolink:BiologicalProcess embryonic lung development The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_1990401 UBERON:0010498 biolink:AnatomicalEntity pseudostratified columnar epithelium A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010498 UBERON:0010499 biolink:AnatomicalEntity pseudostratified ciliated columnar epithelium Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. go-plus.json epithelium pseudostratificatum columnare ciliatum (trachea et bronchi) http://purl.obolibrary.org/obo/UBERON_0010499 CHEBI:17817 biolink:ChemicalSubstance CDP-4-dehydro-3,6-dideoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17817 CHEBI:17818 biolink:ChemicalSubstance N-feruloyltyramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17818 chebi_ph7_3 CHEBI:17815 biolink:ChemicalSubstance 1,2-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17815 chebi_ph7_3 CHEBI:17816 biolink:ChemicalSubstance 1D-myo-inositol 1,4-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17816 CHEBI:17813 biolink:ChemicalSubstance 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17813 chebi_ph7_3 CHEBI:17814 biolink:ChemicalSubstance salicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17814 chebi_ph7_3 CHEBI:17811 biolink:ChemicalSubstance 2,4,6/3,5-pentahydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17811 chebi_ph7_3 CHEBI:17810 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-O-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17810 chebi_ph7_3 GO:1990406 biolink:CellularComponent CGRP receptor complex A transmembrane, G protein-coupled signalling receptor complex recognized by calcitonin gene-related peptides (CGRP). go-plus.json calcitonin gene-related polypeptide receptor complex|CGRP-R complex|Calcitonin-gene-related peptide receptor complex http://purl.obolibrary.org/obo/GO_1990406 GO:1990407 biolink:MolecularActivity calcitonin gene-related peptide binding Binding to calcitonin gene-related peptide (CGRP). go-plus.json calcitonin-gene-related peptide binding|CGRP polypeptide binding|calcitonin-gene-related polypeptide binding http://purl.obolibrary.org/obo/GO_1990407 GO:1990408 biolink:BiologicalProcess calcitonin gene-related peptide receptor signaling pathway A series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers. go-plus.json calcitonin-gene-related peptide receptor signaling pathway|calcitonin-gene-related polypeptide receptor signaling pathway|CGRP receptor signaling pathway http://purl.obolibrary.org/obo/GO_1990408 GO:1990409 biolink:MolecularActivity adrenomedullin binding Binding to adrenomedullin (AM). go-plus.json AM binding http://purl.obolibrary.org/obo/GO_1990409 GO:1990402 biolink:BiologicalProcess embryonic liver development The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_1990402 GO:1990403 biolink:BiologicalProcess embryonic brain development The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_1990403 GO:1990404 biolink:MolecularActivity protein ADP-ribosylase activity The transfer, from NAD, of ADP-ribose to a protein amino acid residue. go-plus.json ribosylase activity http://purl.obolibrary.org/obo/GO_1990404 GO:1990405 biolink:MolecularActivity protein antigen binding Binding to a protein antigen. go-plus.json http://purl.obolibrary.org/obo/GO_1990405 GO:0098026 biolink:CellularComponent virus tail, tube The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm. go-plus.json bacteriophage tail tube http://purl.obolibrary.org/obo/GO_0098026 GO:0098027 biolink:CellularComponent virus tail, sheath The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm. go-plus.json bacteriophage tail sheath http://purl.obolibrary.org/obo/GO_0098027 GO:1990410 biolink:BiologicalProcess adrenomedullin receptor signaling pathway A series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell. go-plus.json AM receptor signaling pathway http://purl.obolibrary.org/obo/GO_1990410 GO:1990411 biolink:MolecularActivity hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium. MetaCyc:RXN-14428|RHEA:42688 go-plus.json http://purl.obolibrary.org/obo/GO_1990411 GO:0098024 biolink:CellularComponent virus tail, fiber The fibrous region of the virus tail used to scan, recognize and attach to the host cell. go-plus.json bacteriophage tail fiber http://purl.obolibrary.org/obo/GO_0098024 GO:0098025 biolink:CellularComponent virus tail, baseplate Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached. go-plus.json bacteriophage baseplate|tail tip|tail structure http://purl.obolibrary.org/obo/GO_0098025 GO:1990412 biolink:MolecularActivity hercynylselenocysteine lyase activity (selenoneine-forming) Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium. RHEA:42696 go-plus.json http://purl.obolibrary.org/obo/GO_1990412 GO:0098022 biolink:CellularComponent viral capsid, fiber A type of capsid decoration composed of fiber structures. go-plus.json head/capsid fiber http://purl.obolibrary.org/obo/GO_0098022 GO:0098023 biolink:CellularComponent virus tail, tip The basal end of the virus tail, which is used by the virus to attach to the host cell. go-plus.json bacteriophage tail tip http://purl.obolibrary.org/obo/GO_0098023 GO:0098020 biolink:CellularComponent obsolete virus tail, minor subunit OBSOLETE. The part of the viral tail that comprises the least common subunit type. go-plus.json bacteriophage minor protein subunit|minor tail protein http://purl.obolibrary.org/obo/GO_0098020 GO:0098021 biolink:CellularComponent viral capsid, decoration Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential. go-plus.json decoration protein http://purl.obolibrary.org/obo/GO_0098021 CHEBI:17848 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17848 CHEBI:17849 biolink:ChemicalSubstance glucarolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17849 CHEBI:17846 biolink:ChemicalSubstance (S)-naringenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17846 chebi_ph7_3 CHEBI:17847 biolink:ChemicalSubstance p-cresol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17847 chebi_ph7_3 CHEBI:17844 biolink:ChemicalSubstance 2-amino-3-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17844 CHEBI:17845 biolink:ChemicalSubstance 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17845 CHEBI:17842 biolink:ChemicalSubstance trypanothione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17842 CHEBI:17843 biolink:ChemicalSubstance transfer RNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_17843 GO:1990417 biolink:BiologicalProcess snoRNA release from pre-rRNA The release of snoRNA from pre-rRNA. go-plus.json http://purl.obolibrary.org/obo/GO_1990417 UBERON:0009494 biolink:AnatomicalEntity pharyngeal arch mesenchymal region A portion of mesenchymal tissue associated with an individual pharyngeal arch. go-plus.json branchial arch mesenchyme|pharyngeal arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 CHEBI:17840 biolink:ChemicalSubstance indoxyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_17840 chebi_ph7_3 GO:1990418 biolink:BiologicalProcess response to insulin-like growth factor stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990418 GO:1990419 biolink:BiologicalProcess obsolete response to elemental metal OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an elemental metal stimulus. go-plus.json response to elemental metal http://purl.obolibrary.org/obo/GO_1990419 UBERON:0009497 biolink:AnatomicalEntity epithelium of foregut-midgut junction An epithelium that is part of a foregut-midgut junction. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009497 GO:1990413 biolink:CellularComponent eyespot apparatus A small pigmented organelle used in single-celled organisms to detect light. go-plus.json stigma|eyespot http://purl.obolibrary.org/obo/GO_1990413 GO:1990414 biolink:BiologicalProcess replication-born double-strand break repair via sister chromatid exchange The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks. go-plus.json replication-born DSB repair by SCE http://purl.obolibrary.org/obo/GO_1990414 GO:0098028 biolink:CellularComponent virus tail, shaft The tube of the non-contractile tails of some viruses. go-plus.json bacteriophage tail shaft http://purl.obolibrary.org/obo/GO_0098028 GO:1990415 biolink:CellularComponent Pex17p-Pex14p docking complex A protein complex involved in the peroxisomal import machinery. In S. cerevisiae, this complex contains the proteins Pex17p, Pex14p, Pex19, and Pex13p. go-plus.json http://purl.obolibrary.org/obo/GO_1990415 GO:1990416 biolink:BiologicalProcess cellular response to brain-derived neurotrophic factor stimulus A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus. go-plus.json cellular response to BDNF stimulus http://purl.obolibrary.org/obo/GO_1990416 GO:0098029 biolink:CellularComponent icosahedral viral capsid, spike A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0098029 GO:0098037 biolink:BiologicalProcess viral DNA genome packaging, 5' extended cos packaging The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends. go-plus.json http://purl.obolibrary.org/obo/GO_0098037 GO:1990420 biolink:BiologicalProcess establishment of septation initiation network asymmetry The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies. go-plus.json establishment of SIN asymmetry http://purl.obolibrary.org/obo/GO_1990420 GO:0098038 biolink:BiologicalProcess non-replicative transposition, DNA-mediated Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition. go-plus.json cut-and-paste transposition http://purl.obolibrary.org/obo/GO_0098038 GO:1990421 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990421 GO:1990422 biolink:MolecularActivity glyoxalase (glycolic acid-forming) activity Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor. go-plus.json http://purl.obolibrary.org/obo/GO_1990422 GO:0098035 biolink:BiologicalProcess viral DNA genome packaging via site-specific sequence recognition The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase. go-plus.json http://purl.obolibrary.org/obo/GO_0098035 GO:1990423 biolink:CellularComponent RZZ complex A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints. go-plus.json Rod-Zwilch-Zw10 complex http://purl.obolibrary.org/obo/GO_1990423 GO:0098036 biolink:BiologicalProcess viral DNA genome packaging, 3' extended cos packaging The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends. go-plus.json http://purl.obolibrary.org/obo/GO_0098036 GO:0098033 biolink:CellularComponent icosahedral viral capsid, neck fiber A fiber attached to the neck at the base of some icosahedral viral capsids. go-plus.json http://purl.obolibrary.org/obo/GO_0098033 UBERON:0009480 biolink:AnatomicalEntity endoderm of buccopharyngeal membrane An endoderm that is part of a buccopharyngeal membrane. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009480 GO:0098031 biolink:CellularComponent icosahedral viral capsid, collar A small disk located at the base of some icosahedral virus capsids. go-plus.json http://purl.obolibrary.org/obo/GO_0098031 GO:0098032 biolink:CellularComponent icosahedral viral capsid, collar fiber A fiber attached to the collar structure of some icosahedral viral capsids. go-plus.json http://purl.obolibrary.org/obo/GO_0098032 UBERON:0009482 biolink:AnatomicalEntity associated mesenchyme of foregut-midgut junction Mesenchyme that is part of a foregut-midgut junction. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009482 GO:0098030 biolink:CellularComponent icosahedral viral capsid, neck A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae). go-plus.json http://purl.obolibrary.org/obo/GO_0098030 CHEBI:17839 biolink:ChemicalSubstance 7,8-dihydropteroate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17839 chebi_ph7_3 CHEBI:17837 biolink:ChemicalSubstance D-tagatose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17837 CHEBI:17838 biolink:ChemicalSubstance (3S)-3-hydroxy-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17838 CHEBI:17835 biolink:ChemicalSubstance 2-phospho-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17835 CHEBI:17836 biolink:ChemicalSubstance 4-aminobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17836 chebi_ph7_3 CHEBI:17833 biolink:ChemicalSubstance gentamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17833 CHEBI:17831 biolink:ChemicalSubstance heparosan-N-sulfate D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17831 CHEBI:17832 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17832 chebi_ph7_3 GO:1990428 biolink:BiologicalProcess miRNA transport The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. go-plus.json microRNA transport http://purl.obolibrary.org/obo/GO_1990428 UBERON:0009483 biolink:AnatomicalEntity mesentery of foregut-midgut junction A mesentery that is part of a foregut-midgut junction. go-plus.json foregut-midgut junction mesentery http://purl.obolibrary.org/obo/UBERON_0009483 GO:1990429 biolink:CellularComponent peroxisomal importomer complex A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners. go-plus.json peroxisomal import pore|Pex14 complex|peroxisomal protein import machinery http://purl.obolibrary.org/obo/GO_1990429 CHEBI:17830 biolink:ChemicalSubstance 7,8-diaminononanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17830 GO:1990424 biolink:MolecularActivity protein arginine kinase activity Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1990424 GO:1990425 biolink:CellularComponent ryanodine receptor complex A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom. go-plus.json RyR http://purl.obolibrary.org/obo/GO_1990425 GO:0098039 biolink:BiologicalProcess replicative transposition, DNA-mediated Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition. go-plus.json transpositional DNA genome replication|copy-and-paste transposition http://purl.obolibrary.org/obo/GO_0098039 GO:1990426 biolink:BiologicalProcess mitotic recombination-dependent replication fork processing Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart. go-plus.json homologous recombination dependent replication fork recovery|homologous recombination-dependent replication fork processing http://purl.obolibrary.org/obo/GO_1990426 GO:1990427 biolink:CellularComponent stereocilia tip-link density An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990427 GO:0098061 biolink:CellularComponent viral capsid, internal space The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins. go-plus.json internal head protein http://purl.obolibrary.org/obo/GO_0098061 CHEBI:17808 biolink:ChemicalSubstance IDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_17808 CHEBI:17806 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_17806 chebi_ph7_3 CHEBI:17807 biolink:ChemicalSubstance 3-(3,4-dihydroxyphenyl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17807 CHEBI:17804 biolink:ChemicalSubstance dyspropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17804 chebi_ph7_3 CHEBI:17805 biolink:ChemicalSubstance D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17805 CHEBI:17802 biolink:ChemicalSubstance pseudouridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17802 chebi_ph7_3 CHEBI:134288 biolink:ChemicalSubstance phosphatidic acid 18:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134288 CHEBI:134289 biolink:ChemicalSubstance xanthohumol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134289 chebi_ph7_3 CHEBI:17803 biolink:ChemicalSubstance dehydro-D-arabinono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17803 CHEBI:17800 biolink:ChemicalSubstance O-phosphoviomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17800 CHEBI:17801 biolink:ChemicalSubstance 4-hydroxy-4-methyl-2-oxoglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17801 CHEBI:134283 biolink:ChemicalSubstance keto-D-tagatose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134283 chebi_ph7_3 CHEBI:134286 biolink:ChemicalSubstance O-succinyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134286 CHEBI:134284 biolink:ChemicalSubstance keto-L-tagatose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134284 chebi_ph7_3 CHEBI:134299 biolink:ChemicalSubstance phosphatidylcholine 13:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134299 chebi_ph7_3 CARO:0001010 biolink:OntologyClass organism or virus or viroid go-plus.json http://purl.obolibrary.org/obo/CARO_0001010 CHEBI:134298 biolink:ChemicalSubstance phosphatidylcholine 12:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134298 chebi_ph7_3 GO:0050026 biolink:MolecularActivity L-glycol dehydrogenase activity Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+. MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN|EC:1.1.1.185 go-plus.json L-(+)-glycol:NAD(P) oxidoreductase activity|L-glycol:NAD(P)+ oxidoreductase activity|glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity|L-glycol:NAD(P) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050026 GO:0050027 biolink:MolecularActivity obsolete L-idonate 2-dehydrogenase activity OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH. MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN|RHEA:21176|EC:1.1.1.128 go-plus.json 5KGR|reductase, 5-ketogluconate 5- (L-idonate-forming)|5-ketogluconate 2-reductase activity|L-idonate 2-dehydrogenase activity|5-keto-D-gluconate 2-reductase activity|L-idonate:NADP+ 2-oxidoreductase activity|5-ketoglucono-idono-reductase activity|L-idonate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050027 GO:0050024 biolink:MolecularActivity L-galactonolactone oxidase activity Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+). MetaCyc:1.3.3.12-RXN|RHEA:20617|EC:1.3.3.12|KEGG_REACTION:R00643 go-plus.json L-xylono-1,4-lactone oxidase activity|L-galactono-1,4-lactone oxidase activity|L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050024 GO:0050025 biolink:MolecularActivity L-glutamate oxidase activity Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2. RHEA:20728|EC:1.4.3.11|MetaCyc:L-GLUTAMATE-OXIDASE-RXN go-plus.json glutamate (acceptor) dehydrogenase activity|glutamate oxidase activity|glutamic dehydrogenase (acceptor)|L-glutamate:oxygen oxidoreductase (deaminating)|L-glutamic acid oxidase activity|glutamic acid oxidase activity http://purl.obolibrary.org/obo/GO_0050025 CHEBI:27237 biolink:ChemicalSubstance uridine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27237 GO:0050028 biolink:MolecularActivity L-lysine-lactamase activity Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine. MetaCyc:L-LYSINE-LACTAMASE-RXN|RHEA:21388|EC:3.5.2.11|KEGG_REACTION:R00463 go-plus.json L-alpha-aminocaprolactam hydrolase activity|L-lysine-1,6-lactam lactamhydrolase activity|L-lysinamidase activity http://purl.obolibrary.org/obo/GO_0050028 GO:0050029 biolink:MolecularActivity L-lysine oxidase activity Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+). MetaCyc:L-LYSINE-OXIDASE-RXN|EC:1.4.3.14|KEGG_REACTION:R00447|RHEA:14437|MetaCyc:PWY-5311 go-plus.json L-lysyl-alpha-oxidase activity|L-lysine:oxygen 2-oxidoreductase (deaminating)|L-lysine alpha-oxidase activity http://purl.obolibrary.org/obo/GO_0050029 CHEBI:27232 biolink:ChemicalSubstance uridine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27232 CL:0000765 biolink:Cell erythroblast A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. go-plus.json normoblast http://purl.obolibrary.org/obo/CL_0000765 CL:0000766 biolink:Cell myeloid leukocyte A cell of the monocyte, granulocyte, or mast cell lineage. go-plus.json http://purl.obolibrary.org/obo/CL_0000766 CL:0000767 biolink:Cell basophil Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. go-plus.json basophilic leucocyte|basophilic leukocyte|polymorphonuclear leucocyte|polymorphonuclear leukocyte http://purl.obolibrary.org/obo/CL_0000767 CL:0000768 biolink:Cell immature basophil Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. go-plus.json immature basophilic leukocyte|immature basophilic leucocyte http://purl.obolibrary.org/obo/CL_0000768 UBERON:0010421 biolink:AnatomicalEntity spleen B cell corona The area of the (spleen) secondary B follicle that surrounds the germinal center and harbors the small recirculating B lymphocytes go-plus.json spleen B-cell corona|splenic B cell corona|splenic corona|spleen lymphocytic corona|spleen B cell corona|follicle mantle|spleen mantle zone|B lymphocyte domain of the spleen|lymphocytic corona|B cell domain of the spleen http://purl.obolibrary.org/obo/UBERON_0010421 CL:0000769 biolink:Cell basophilic metamyelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0000769 UBERON:0010422 biolink:AnatomicalEntity primary nodular lymphoid tissue A lymphoid follicle containing naive B cells go-plus.json primary lymphoid follicle|primary lymphoid nodule|primary follicle http://purl.obolibrary.org/obo/UBERON_0010422 UBERON:0010420 biolink:AnatomicalEntity lymph node germinal center mantle zone A part of the secondary follicle in which naive B cells reside along with some helper T cells, macrophages and follicular dendritic cells; these are displaced by the expanding germinal centre and form a 'mantle' around it. go-plus.json lymph node inactive zone|lymph node B cell corona|mantle zone of germinal center|lymph node follicular corona|lymph node dark zone|lymph node peripheral zone|germinal center mantle zone|mantle zone of lymph node germinal center|lymph node follicular mantle http://purl.obolibrary.org/obo/UBERON_0010420 UBERON:0010412 biolink:AnatomicalEntity epididymal fat pad encapsulated adipose tissue associated with the epididymis go-plus.json periepididymal fat pad http://purl.obolibrary.org/obo/UBERON_0010412 UBERON:0010418 biolink:AnatomicalEntity urethral opening An orifice that is part of a lower urinary tract. go-plus.json urethral orifice http://purl.obolibrary.org/obo/UBERON_0010418 CL:0000762 biolink:Cell nucleated thrombocyte A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. go-plus.json http://purl.obolibrary.org/obo/CL_0000762 UBERON:0010416 biolink:AnatomicalEntity lymph node B cell domain A part of the lymph node cortex in which B lymphocytes home to primary follicles to survey follicular dendritic cells (FDCs); antigen stimulated B cells proliferate and differentiate within the follicles forming distinctive germinal centers go-plus.json nodular lymph node cortex|lymph node B-cell domain|lymph node B cell dependent cortex http://purl.obolibrary.org/obo/UBERON_0010416 CL:0000763 biolink:Cell myeloid cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. go-plus.json http://purl.obolibrary.org/obo/CL_0000763 NCBITaxon:49274 biolink:OrganismalEntity Solanum subgen. Lycopersicon go-plus.json Lycopersicon http://purl.obolibrary.org/obo/NCBITaxon_49274 UBERON:0010417 biolink:AnatomicalEntity lymph node T cell domain The paracortex and interfollicular cortex of the lymph node in which T lymphocytes home to survey dendritic cells go-plus.json lymph node deep cortex|lymph node T cell dependent paracortex|lymph node T-cell domain|T cell zone of lymph node|lymph node T zone|T zone of lymph node http://purl.obolibrary.org/obo/UBERON_0010417 CL:0000764 biolink:Cell erythroid lineage cell A immature or mature cell in the lineage leading to and including erythrocytes. go-plus.json erythropoietic cell http://purl.obolibrary.org/obo/CL_0000764 GO:0050022 biolink:MolecularActivity L-arabinose 1-dehydrogenase (NAD+) activity Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH. MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.46|RHEA:17925 go-plus.json L-arabinose 1-dehydrogenase activity|L-arabinose:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050022 GO:0050023 biolink:MolecularActivity L-fuconate dehydratase activity Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O. MetaCyc:L-FUCONATE-HYDRATASE-RXN|EC:4.2.1.68|KEGG_REACTION:R03688|RHEA:22772 go-plus.json L-fuconate hydro-lyase activity|L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)|L-fuconate hydratase activity http://purl.obolibrary.org/obo/GO_0050023 GO:0050020 biolink:MolecularActivity L-arabinonate dehydratase activity Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O. MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN|RHEA:20968|EC:4.2.1.25|KEGG_REACTION:R02522 go-plus.json L-arabinonate hydro-lyase activity|L-arabonate dehydrase activity|L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)|L-arabonate dehydratase activity http://purl.obolibrary.org/obo/GO_0050020 GO:0050021 biolink:MolecularActivity L-arabinonolactonase activity Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+). MetaCyc:L-ARABINONOLACTONASE-RXN|EC:3.1.1.15|KEGG_REACTION:R02526|RHEA:16217 go-plus.json L-arabinono-1,4-lactone lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0050021 GO:0050037 biolink:MolecularActivity L-xylose 1-dehydrogenase activity Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH. MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN|RHEA:15789|KEGG_REACTION:R03586|EC:1.1.1.113 go-plus.json L-xylose:NADP+ 1-oxidoreductase activity|L-xylose dehydrogenase activity|NADPH-xylose reductase activity http://purl.obolibrary.org/obo/GO_0050037 GO:0050038 biolink:MolecularActivity L-xylulose reductase (NADP+) activity Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH. KEGG_REACTION:R01904|EC:1.1.1.10|Reactome:R-HSA-5661240|Reactome:R-HSA-5662851|RHEA:17025|MetaCyc:L-XYLULOSE-REDUCTASE-RXN go-plus.json L-xylulose reductase activity http://purl.obolibrary.org/obo/GO_0050038 GO:0050035 biolink:MolecularActivity L-sorbose oxidase activity Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2). EC:1.1.3.11|KEGG_REACTION:R01695|RHEA:17853|MetaCyc:L-SORBOSE-OXIDASE-RXN go-plus.json L-sorbose:oxygen 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050035 GO:0050036 biolink:MolecularActivity L-threonate 3-dehydrogenase activity Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH. KEGG_REACTION:R03733|RHEA:23376|EC:1.1.1.129|MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN go-plus.json threonate dehydrogenase activity|L-threonate:NAD+ 3-oxidoreductase activity|L-threonic acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050036 CHEBI:27247 biolink:ChemicalSubstance urocanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27247 chebi_ph7_3 CHEBI:27248 biolink:ChemicalSubstance urocanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27248 GO:0050039 biolink:MolecularActivity lactaldehyde reductase (NADPH) activity Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH. EC:1.1.1.55|KEGG_REACTION:R02259|RHEA:15885|MetaCyc:LACTALDEHYDE-REDUCTASE-NADPH-RXN go-plus.json propane-1,2-diol:NADP+ oxidoreductase activity|1,2-propanediol:NADP+ oxidoreductase activity|lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADP-1,2-propanediol dehydrogenase activity|propanediol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050039 GO:0015708 biolink:BiologicalProcess silicic acid import across plasma membrane The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates. go-plus.json silicic acid transport|silicon uptake|silicic acid import|silicate transport http://purl.obolibrary.org/obo/GO_0015708 CL:0000776 biolink:Cell immature neutrophil Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking. go-plus.json immature neutrophil leucocyte|immature neutrocyte|immature neutrophilic leucocyte|immatuer neutrophilic leukocyte|immature neutrophil leukocyte http://purl.obolibrary.org/obo/CL_0000776 GO:0015709 biolink:BiologicalProcess thiosulfate transport The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json thiosulphate transport http://purl.obolibrary.org/obo/GO_0015709 CL:0000777 biolink:Cell mesangial phagocyte A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. go-plus.json mesangial cell http://purl.obolibrary.org/obo/CL_0000777 CL:0000778 biolink:Cell mononuclear osteoclast A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. go-plus.json http://purl.obolibrary.org/obo/CL_0000778 CL:0000779 biolink:Cell multinuclear osteoclast A specialized multinuclear osteoclast associated with the absorption and removal of bone. go-plus.json multinucleated osteoclast http://purl.obolibrary.org/obo/CL_0000779 GO:0015704 biolink:BiologicalProcess cyanate transport The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015704 GO:0015705 biolink:BiologicalProcess iodide transport The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015705 UBERON:0010411 biolink:AnatomicalEntity retroperitoneal fat pad encapsulated adipose tissue found on the dorsal side of the peritoneum go-plus.json retroperitoneal fat depot http://purl.obolibrary.org/obo/UBERON_0010411 GO:0015706 biolink:BiologicalProcess nitrate transport The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json low-affinity nitrate transport|low affinity nitrate transport http://purl.obolibrary.org/obo/GO_0015706 CHEBI:27242 biolink:ChemicalSubstance uridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_27242 GO:0015707 biolink:BiologicalProcess nitrite transport The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015707 GO:0015700 biolink:BiologicalProcess arsenite transport The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015700 GO:0015701 biolink:BiologicalProcess bicarbonate transport The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015701 GO:0015702 biolink:BiologicalProcess chlorate transport The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015702 CL:0000770 biolink:Cell band form basophil A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. go-plus.json http://purl.obolibrary.org/obo/CL_0000770 CL:0000771 biolink:Cell eosinophil Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. go-plus.json polymorphonuclear leucocyte|polymorphonuclear leukocyte|eosinocyte|eosinophilic leucocyte|eosinophilic granulocyte|eosinophilic leukocyte http://purl.obolibrary.org/obo/CL_0000771 GO:0015703 biolink:BiologicalProcess chromate transport The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015703 CL:0000772 biolink:Cell immature eosinophil Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking. go-plus.json immature eosinophilic leucocyte|immature eosinophilic leukocyte|immature eosinocyte http://purl.obolibrary.org/obo/CL_0000772 CHEBI:17899 biolink:ChemicalSubstance 7alpha-hydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17899 chebi_ph7_3 CL:0000773 biolink:Cell eosinophilic metamyelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0000773 CL:0000774 biolink:Cell band form eosinophil A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil. go-plus.json http://purl.obolibrary.org/obo/CL_0000774 CHEBI:17897 biolink:ChemicalSubstance L-rhamnulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17897 chebi_ph7_3 CL:0000775 biolink:Cell neutrophil Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. go-plus.json neutrocyte|polymorphonuclear leucocyte|neutrophilic leucocyte|neutrophil leukocyte|polynuclear neutrophilic leucocyte|polymorphonuclear neutrophil|neutrophilic leukocyte|polymorphonuclear leukocyte|polynuclear neutrophilic leukocyte|PMN|poly|neutrophil leucocyte http://purl.obolibrary.org/obo/CL_0000775 CHEBI:17898 biolink:ChemicalSubstance all-trans-retinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17898 chebi_ph7_3 CHEBI:17895 biolink:ChemicalSubstance L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17895 GO:0050030 biolink:MolecularActivity L-pipecolate dehydrogenase activity Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate. MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN|RHEA:19777|EC:1.5.99.3 go-plus.json L-pipecolate:(acceptor) 1,6-oxidoreductase activity|L-pipecolate:acceptor 1,6-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050030 UBERON:0010409 biolink:AnatomicalEntity ocular surface region The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms. go-plus.json ocular surface|eye surface|eye surface region http://purl.obolibrary.org/obo/UBERON_0010409 CHEBI:17893 biolink:ChemicalSubstance (2R)-2-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17893 GO:0050033 biolink:MolecularActivity L-rhamnono-1,4-lactonase activity Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+). MetaCyc:L-RHAMNONO-14-LACTONASE-RXN|EC:3.1.1.65|RHEA:10288|KEGG_REACTION:R03772 go-plus.json L-rhamno-gamma-lactonase activity|L-rhamnono-gamma-lactonase activity|L-rhamnono-1,4-lactone lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0050033 CHEBI:17891 biolink:ChemicalSubstance donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_17891 GO:0050034 biolink:MolecularActivity L-rhamnose 1-dehydrogenase activity Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH. RHEA:12649|KEGG_REACTION:R03942|MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.173 go-plus.json L-rhamnofuranose:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050034 CHEBI:17892 biolink:ChemicalSubstance L-rhamnulose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17892 GO:0050031 biolink:MolecularActivity L-pipecolate oxidase activity Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate. MetaCyc:L-PIPECOLATE-OXIDASE-RXN|KEGG_REACTION:R02204|EC:1.5.3.7|RHEA:11992|Reactome:R-HSA-6783880 go-plus.json L-pipecolic acid oxidase activity|L-pipecolate:oxygen 1,6-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050031 CHEBI:17890 biolink:ChemicalSubstance tryptophol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17890 chebi_ph7_3 GO:0050032 biolink:MolecularActivity L-rhamnonate dehydratase activity Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O. KEGG_REACTION:R03774|MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN|EC:4.2.1.90|RHEA:23080 go-plus.json L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)|L-rhamnonate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0050032 GO:0050048 biolink:MolecularActivity L-leucine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate. RHEA:18321|MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN|EC:2.6.1.6 go-plus.json leucine-alpha-ketoglutarate transaminase activity|L-leucine aminotransferase activity|leucine aminotransferase activity|leucine 2-oxoglutarate transaminase activity|leucine transaminase activity http://purl.obolibrary.org/obo/GO_0050048 GO:0050049 biolink:MolecularActivity leucine dehydrogenase activity Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH. MetaCyc:LEUCINE-DEHYDROGENASE-RXN|RHEA:12220|EC:1.4.1.9 go-plus.json L-leucine:NAD+ oxidoreductase, deaminating|LeuDH activity|L-leucine:NAD+ oxidoreductase (deaminating)|L-leucine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050049 GO:0050046 biolink:MolecularActivity delta7-sterol 5(6)-desaturase activity Catalysis of the reaction: a delta(7)-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ -> a delta(5,7)-sterol + 2 ferricytochrome b5 + 2 H2O. MetaCyc:1.14.21.6-RXN|EC:1.14.19.20|RHEA:46556 go-plus.json delta7-sterol 5-desaturase activity|delta7-sterol-C5(6)-desaturase activity|delta7-sterol delta5-dehydrogenase activity|5-DES|lathosterol oxidase activity|lathosterol 5-desaturase activity http://purl.obolibrary.org/obo/GO_0050046 GO:0050047 biolink:MolecularActivity leucine 2,3-aminomutase activity Catalysis of the reaction: L-leucine = (3R)-beta-leucine. KEGG_REACTION:R01091|MetaCyc:LEUCINE-23-AMINOMUTASE-RXN|EC:5.4.3.7|RHEA:10284 go-plus.json (2S)-alpha-leucine 2,3-aminomutase activity http://purl.obolibrary.org/obo/GO_0050047 CHEBI:27216 biolink:ChemicalSubstance urate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_27216 CL:0000746 biolink:Cell cardiac muscle cell Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. go-plus.json cardiocyte|cardiac myocyte|cardiac muscle fiber|heart muscle cell|cardiomyocyte http://purl.obolibrary.org/obo/CL_0000746 CL:0000747 biolink:Cell cyanophore A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. go-plus.json blue chromatophore http://purl.obolibrary.org/obo/CL_0000747 UBERON:0010400 biolink:AnatomicalEntity spleen trabecular vein one of the veins that feed the splenic vein go-plus.json trabecular vein http://purl.obolibrary.org/obo/UBERON_0010400 CL:0000748 biolink:Cell retinal bipolar neuron A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer. go-plus.json http://purl.obolibrary.org/obo/CL_0000748 CL:0000740 biolink:Cell retinal ganglion cell The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. go-plus.json RGC|gangliocyte|ganglion cell of retina http://purl.obolibrary.org/obo/CL_0000740 GO:0050040 biolink:MolecularActivity lactate 2-monooxygenase activity Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O. MetaCyc:LACTATE-2-MONOOXYGENASE-RXN|EC:1.13.12.4|KEGG_REACTION:R00319|RHEA:16513 go-plus.json lactate oxygenase activity|lactic oxidase activity|(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)|lactic oxygenase activity|L-lactate-2-monooxygenase activity|lactate oxidative decarboxylase activity|L-lactate monooxygenase activity|lactate oxidase activity|lactate monooxygenase activity http://purl.obolibrary.org/obo/GO_0050040 GO:0050041 biolink:MolecularActivity lactate aldolase activity Catalysis of the reaction: (S)-lactate = acetaldehyde + formate. RHEA:17909|EC:4.1.2.36|KEGG_REACTION:R00753|MetaCyc:LACTATE-ALDOLASE-RXN go-plus.json lactate synthase activity|(S)-lactate acetaldehyde-lyase activity|(S)-lactate acetaldehyde-lyase (formate-forming) http://purl.obolibrary.org/obo/GO_0050041 GO:0050044 biolink:MolecularActivity galactose-6-phosphate isomerase activity Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate. EC:5.3.1.26|MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN|RHEA:13033|KEGG_REACTION:R03240 go-plus.json D-galactose-6-phosphate aldose-ketose-isomerase activity|D-galactose-6-phosphate ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0050044 GO:0050045 biolink:MolecularActivity laminaribiose phosphorylase activity Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate. MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN|RHEA:16617|EC:2.4.1.31 go-plus.json 3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050045 GO:0050042 biolink:MolecularActivity lactate-malate transhydrogenase activity Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate. EC:1.1.99.7|KEGG_REACTION:R01447|RHEA:10984|MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN go-plus.json (S)-lactate:oxaloacetate oxidoreductase activity|malate-lactate transhydrogenase activity http://purl.obolibrary.org/obo/GO_0050042 GO:0050043 biolink:MolecularActivity lactate racemase activity Catalysis of the reaction: (S)-lactate = (R)-lactate. EC:5.1.2.1|RHEA:10960|KEGG_REACTION:R01450|MetaCyc:LACTATE-RACEMASE-RXN go-plus.json lactic acid racemase activity|lacticoracemase activity|hydroxyacid racemase activity http://purl.obolibrary.org/obo/GO_0050043 GO:0050059 biolink:MolecularActivity lombricine kinase activity Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine. MetaCyc:LOMBRICINE-KINASE-RXN|EC:2.7.3.5|RHEA:23292 go-plus.json ATP:lombricine N-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050059 GO:0050057 biolink:MolecularActivity linamarin synthase activity Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin. RHEA:20009|EC:2.4.1.63|MetaCyc:LINAMARIN-SYNTHASE-RXN go-plus.json UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-ketone glucosyltransferase activity|UDP glucose ketone cyanohydrin glucosyltransferase activity|uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity|UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity|uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050057 GO:0050058 biolink:MolecularActivity linoleate isomerase activity Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate. KEGG_REACTION:R03627|EC:5.2.1.5|RHEA:17381|MetaCyc:LINOLEATE-ISOMERASE-RXN go-plus.json linoleic acid isomerase activity|linoleate delta12-cis-delta11-trans-isomerase activity http://purl.obolibrary.org/obo/GO_0050058 CHEBI:27226 biolink:ChemicalSubstance uric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27226 CL:0000751 biolink:Cell rod bipolar cell A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light. go-plus.json http://purl.obolibrary.org/obo/CL_0000751 CL:0000752 biolink:Cell cone retinal bipolar cell A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. go-plus.json http://purl.obolibrary.org/obo/CL_0000752 GO:0050051 biolink:MolecularActivity leukotriene-B4 20-monooxygenase activity Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN|RHEA:22176|Reactome:R-HSA-211873|EC:1.14.14.94 go-plus.json leukotriene-B4 omega-hydroxylase activity|leukotriene-B4 20-hydroxylase activity|LTB(4) 20-hydroxylase activity|LTB4 omega-hydroxylase activity|LTB(4) omega-hydroxylase activity|LTB4 20-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050051 GO:0050052 biolink:MolecularActivity leukotriene-E4 20-monooxygenase activity Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+). MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN|KEGG_REACTION:R04256|RHEA:24120|EC:1.14.13.34 go-plus.json (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)|leukotriene-E4 omega-hydroxylase activity|leukotriene-E4 w-hydroxylase activity|leukotriene-E(4) omega-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050052 GO:0050050 biolink:MolecularActivity leucine N-acetyltransferase activity Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+). EC:2.3.1.66|RHEA:20089|KEGG_REACTION:R01089|MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN go-plus.json leucine acetyltransferase activity|acetyl-CoA:L-leucine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050050 GO:0050055 biolink:MolecularActivity limonin-D-ring-lactonase activity Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate. RHEA:10896|MetaCyc:LIMONIN-D-RING-LACTONASE-RXN|EC:3.1.1.36 go-plus.json limonin-D-ring-lactone hydrolase activity|limonoate-D-ring-lactone lactonohydrolase activity|limonin lactone hydrolase activity http://purl.obolibrary.org/obo/GO_0050055 GO:0050056 biolink:MolecularActivity linalool 8-monooxygenase activity Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O. RHEA:20760|MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN|KEGG_REACTION:R04366|EC:1.14.99.28 go-plus.json 3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating) http://purl.obolibrary.org/obo/GO_0050056 GO:0050053 biolink:MolecularActivity levansucrase activity Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1). EC:2.4.1.10|RHEA:13653|MetaCyc:LEVANSUCRASE-RXN go-plus.json sucrose 6-fructosyltransferase activity|sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity|beta-2,6-fructosyltransferase activity|beta-2,6-fructan:D-glucose 1-fructosyltransferase activity|sucrose 6-fructosyl transferase activity http://purl.obolibrary.org/obo/GO_0050053 GO:0050054 biolink:MolecularActivity lignostilbene alpha beta-dioxygenase activity Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin. MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN|KEGG_REACTION:R00043|RHEA:21340|EC:1.13.11.43 go-plus.json lignostilbene alphabeta-dioxygenase activity|1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)|lignostilbene ab-dioxygenase activity http://purl.obolibrary.org/obo/GO_0050054 GO:0098004 biolink:BiologicalProcess virus tail fiber assembly The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0098004 GO:0098005 biolink:BiologicalProcess viral head-tail joining Process by which virus heads and tails are attached to each other. go-plus.json phage head tail joining|virus head-tail joining http://purl.obolibrary.org/obo/GO_0098005 GO:0050068 biolink:MolecularActivity lysine carbamoyltransferase activity Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate. RHEA:17121|MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN|KEGG_REACTION:R01396|EC:2.1.3.8 go-plus.json lysine transcarbamylase activity|carbamoyl-phosphate:L-lysine carbamoyltransferase activity http://purl.obolibrary.org/obo/GO_0050068 GO:0098002 biolink:BiologicalProcess receptor-mediated bacteriophage irreversible attachment to host cell The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell. go-plus.json phage irreversible adsorption|irreversible bacteriophage attachment, binding of host cell surface receptor http://purl.obolibrary.org/obo/GO_0098002 GO:0050069 biolink:MolecularActivity lysine dehydrogenase activity Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH. EC:1.4.1.15|MetaCyc:LYSINE-DEHYDROGENASE-RXN|RHEA:18505 go-plus.json L-lysine:NAD+ oxidoreductase (deaminating, cyclizing) http://purl.obolibrary.org/obo/GO_0050069 GO:0098003 biolink:BiologicalProcess viral tail assembly The aggregation, arrangement and bonding together of a set of components to form a virus tail. go-plus.json virus tail assembly|bacteriophage tail assembly http://purl.obolibrary.org/obo/GO_0098003 GO:0098001 biolink:BiologicalProcess receptor-mediated bacteriophage reversible attachment to host cell Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection. go-plus.json reversible bacteriophage attachment, binding of host cell surface receptor|phage reversible adsorption http://purl.obolibrary.org/obo/GO_0098001 UBERON:0009471 biolink:AnatomicalEntity dorsum of tongue The superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis). go-plus.json dorsum linguae|tongue dorsum|dorsal tongue http://purl.obolibrary.org/obo/UBERON_0009471 CL:0000722 biolink:Cell cystoblast go-plus.json http://purl.obolibrary.org/obo/CL_0000722 CL:0000723 biolink:Cell somatic stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. go-plus.json http://purl.obolibrary.org/obo/CL_0000723 CL:0000724 biolink:Cell heterocyst A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions. go-plus.json http://purl.obolibrary.org/obo/CL_0000724 CL:0000725 biolink:Cell nitrogen fixing cell go-plus.json http://purl.obolibrary.org/obo/CL_0000725 CL:0000726 biolink:Cell chlamydospore An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material. go-plus.json http://purl.obolibrary.org/obo/CL_0000726 CHEBI:17868 biolink:ChemicalSubstance 1-palmitoylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17868 CHEBI:17869 biolink:ChemicalSubstance 6-hydroxyhexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17869 CHEBI:17866 biolink:ChemicalSubstance digallate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17866 chebi_ph7_3 CHEBI:17867 biolink:ChemicalSubstance UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17867 CHEBI:17864 biolink:ChemicalSubstance taurolithocholic acid sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17864 CHEBI:17865 biolink:ChemicalSubstance 4-methyl-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17865 chebi_ph7_3 UBERON:0009472 biolink:AnatomicalEntity axilla The axilla is the area directly under the joint where the forelimb connects to the shoulder. go-plus.json axilla|regio axillaris|underarm|armpit|axillary region|axillary region|arm pit|oxter|axillae|armpits http://purl.obolibrary.org/obo/UBERON_0009472 GO:0050062 biolink:MolecularActivity long-chain-fatty-acyl-CoA reductase activity Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH. EC:1.2.1.50|RHEA:15437|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN go-plus.json long-chain fatty acyl-CoA reductase activity|acyl coenzyme A reductase activity|long-chain fatty acyl CoA reductase activity|long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming) http://purl.obolibrary.org/obo/GO_0050062 CHEBI:17862 biolink:ChemicalSubstance 3-dehydrosphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17862 GO:0050063 biolink:MolecularActivity obsolete low-density-lipoprotein particle receptor kinase activity OBSOLETE. Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine. MetaCyc:2.7.11.29-RXN|EC:2.7.11.29 go-plus.json LDL receptor kinase activity|low-density-lipoprotein receptor kinase (phosphorylating) activity|low-density lipoprotein receptor kinase activity|low-density-lipoprotein kinase activity|low-density-lipoprotein receptor kinase activity|STK7|ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity|ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity|[low-density lipoprotein receptor] kinase activity http://purl.obolibrary.org/obo/GO_0050063 CHEBI:17863 biolink:ChemicalSubstance cellobiono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17863 chebi_ph7_3 CHEBI:17860 biolink:ChemicalSubstance 6-phospho-2-dehydro-3-deoxy-D-galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17860 GO:0050060 biolink:MolecularActivity long-chain-alcohol dehydrogenase activity Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH. EC:1.1.1.192|RHEA:17977|MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN go-plus.json fatty alcohol oxidoreductase activity|long-chain-alcohol:NAD+ oxidoreductase activity|long-chain alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050060 GO:0050061 biolink:MolecularActivity long-chain-aldehyde dehydrogenase activity Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons. EC:1.2.1.48|UM-BBD_reactionID:r1404|RHEA:10652|MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN go-plus.json long-chain-aldehyde:NAD+ oxidoreductase activity|long-chain aliphatic aldehyde dehydrogenase activity|fatty aldehyde:NAD+ oxidoreductase activity|long-chain fatty aldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050061 CHEBI:17861 biolink:ChemicalSubstance 4-chlorobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17861 chebi_ph7_3 GO:0050066 biolink:MolecularActivity lysine 2,3-aminomutase activity Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate. RHEA:19177|MetaCyc:LYSINE-23-AMINOMUTASE-RXN|KEGG_REACTION:R00461|EC:5.4.3.2 go-plus.json L-lysine 2,3-aminomutase activity http://purl.obolibrary.org/obo/GO_0050066 GO:0098009 biolink:CellularComponent viral terminase, large subunit The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit. go-plus.json virus terminase, large subunit http://purl.obolibrary.org/obo/GO_0098009 GO:0050067 biolink:MolecularActivity lysine 2-monooxygenase activity Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O. EC:1.13.12.2|KEGG_REACTION:R00449|MetaCyc:LYSINE-2-MONOOXYGENASE-RXN|RHEA:14601 go-plus.json L-lysine-2-monooxygenase activity|lysine monooxygenase activity|lysine oxygenase activity|L-lysine:oxygen 2-oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0050067 UBERON:0009477 biolink:AnatomicalEntity associated mesenchyme of otic placode Mesenchyme that is part of a otic placode. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009477 GO:0098006 biolink:BiologicalProcess viral DNA genome packaging, headful The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full. go-plus.json phage headful packaging http://purl.obolibrary.org/obo/GO_0098006 GO:0050064 biolink:MolecularActivity luteolin 7-O-glucuronosyltransferase activity Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP. RHEA:10568|KEGG_REACTION:R03589|MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN|EC:2.4.1.189 go-plus.json UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity|luteolin 7-O-glucoronosyltransferase activity|uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity|LGT http://purl.obolibrary.org/obo/GO_0050064 GO:0050065 biolink:MolecularActivity lysine-pyruvate 6-transaminase activity Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine. RHEA:19393|MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN|MetaCyc:PWY-5324|KEGG_REACTION:R00453|EC:2.6.1.71 go-plus.json Lys-AT|L-lysine:pyruvate aminotransferase activity|lysine--pyruvate 6-aminotransferase activity|lysine-pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0050065 UBERON:0009479 biolink:AnatomicalEntity ectoderm of buccopharyngeal membrane An ectoderm that is part of a buccopharyngeal membrane. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009479 GO:0098015 biolink:CellularComponent virus tail Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell. go-plus.json viral tail|bacteriophage tail http://purl.obolibrary.org/obo/GO_0098015 CHEBI:27207 biolink:ChemicalSubstance univalent carboacyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_27207 CHEBI:27208 biolink:ChemicalSubstance unsaturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27208 GO:0050079 biolink:MolecularActivity acetylenecarboxylate hydratase activity, producing 3-oxopropanoate Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O. RHEA:17957|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN|EC:4.2.1.27 go-plus.json malonate-semialdehyde dehydratase activity|alkynoate hydratase activity|acetylenecarboxylate hydratase activity, producing malonate-semialdehyde|acetylenemonocarboxylate hydrase activity|3-oxopropanoate hydro-lyase (propynoate-forming)|acetylmonocarboxylic acid hydrase activity|3-oxopropanoate hydro-lyase activity|acetylenemonocarboxylate hydratase activity|acetylenecarboxylate hydratase activity http://purl.obolibrary.org/obo/GO_0050079 CL:0000733 biolink:Cell lymph gland plasmatocyte go-plus.json http://purl.obolibrary.org/obo/CL_0000733 CL:0000735 biolink:Cell lymph gland hemocyte go-plus.json http://purl.obolibrary.org/obo/CL_0000735 CL:0000736 biolink:Cell embryonic gland hemocyte go-plus.json http://purl.obolibrary.org/obo/CL_0000736 CL:0000737 biolink:Cell striated muscle cell Muscle cell which has as its direct parts myofilaments organized into sarcomeres. go-plus.json http://purl.obolibrary.org/obo/CL_0000737 CL:0000738 biolink:Cell leukocyte An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. go-plus.json white blood cell|immune cell|leucocyte http://purl.obolibrary.org/obo/CL_0000738 CHEBI:17859 biolink:ChemicalSubstance glutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17859 CHEBI:17857 biolink:ChemicalSubstance 4-methyl-5-(2-phosphonooxyethyl)thiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_17857 CHEBI:17858 biolink:ChemicalSubstance glutathione disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17858 CHEBI:17855 biolink:ChemicalSubstance triglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_17855 chebi_ph7_3 GO:0050070 biolink:MolecularActivity lysolecithin acylmutase activity Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine. KEGG_REACTION:R03334|RHEA:24356|EC:5.4.1.1|MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN go-plus.json lysolecithin 2,3-acylmutase activity|lysolecithin migratase activity http://purl.obolibrary.org/obo/GO_0050070 CHEBI:17856 biolink:ChemicalSubstance glucuronoxylan 4-O-methyl-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17856 CHEBI:42820 biolink:ChemicalSubstance guanidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_42820 CL:0000730 biolink:Cell leading edge cell A cell at the front of a migrating epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/CL_0000730 CHEBI:17853 biolink:ChemicalSubstance S-acetylcysteamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17853 CL:0000731 biolink:Cell urothelial cell A cell of a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. go-plus.json transitional epithelial cell of urinary bladder|urinary tract transitional epithelial cell|bladder transitional cell http://purl.obolibrary.org/obo/CL_0000731 CHEBI:17854 biolink:ChemicalSubstance cyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17854 chebi_ph7_3 GO:0050073 biolink:MolecularActivity macrolide 2'-kinase activity Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate. MetaCyc:MACROLIDE-2-KINASE-RXN|EC:2.7.1.136|KEGG_REACTION:R03780|RHEA:18333 go-plus.json ATP:macrolide 2'-O-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050073 CHEBI:17852 biolink:ChemicalSubstance homocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17852 GO:0050074 biolink:MolecularActivity malate-CoA ligase activity Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA. EC:6.2.1.9|MetaCyc:MALATE--COA-LIGASE-RXN|RHEA:26193 go-plus.json malate thiokinase activity|malyl coenzyme A synthetase activity|malate:CoA ligase (ADP-forming)|malyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0050074 GO:0050071 biolink:MolecularActivity lysyltransferase activity Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol. EC:2.3.2.3|MetaCyc:LYSYLTRANSFERASE-RXN|RHEA:10668 go-plus.json L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity|L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity http://purl.obolibrary.org/obo/GO_0050071 GO:0050072 biolink:MolecularActivity m7G(5')pppN diphosphatase activity Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide. EC:3.6.1.30|MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN go-plus.json 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|m7G(5')pppN pyrophosphatase activity|M(7)G(5')pppN pyrophosphatase activity|decapase activity http://purl.obolibrary.org/obo/GO_0050072 CHEBI:17850 biolink:ChemicalSubstance beta-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(beta-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_17850 GO:0098019 biolink:CellularComponent obsolete virus tail, major subunit OBSOLETE. The part of the viral tail that comprises the most common subunit type. go-plus.json major tail protein http://purl.obolibrary.org/obo/GO_0098019 GO:0050077 biolink:MolecularActivity maleylpyruvate isomerase activity Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate. EC:5.2.1.4|MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN|RHEA:17393 go-plus.json 3-maleylpyruvate cis-trans-isomerase activity http://purl.obolibrary.org/obo/GO_0050077 GO:0050078 biolink:MolecularActivity malonate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA. KEGG_REACTION:R00743|RHEA:18817|MetaCyc:MALONATE-COA-TRANSFERASE-RXN|EC:2.8.3.3 go-plus.json malonate coenzyme A-transferase activity|acetyl-CoA:malonate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0050078 GO:0098017 biolink:CellularComponent viral capsid, major subunit The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits. go-plus.json major capsomere|major head protein http://purl.obolibrary.org/obo/GO_0098017 GO:0050075 biolink:MolecularActivity maleate hydratase activity Catalysis of the reaction: (R)-malate = H(2)O + maleate. EC:4.2.1.31|RHEA:23692|MetaCyc:MALEATE-HYDRATASE-RXN|KEGG_REACTION:R02419 go-plus.json (R)-malate hydro-lyase (maleate-forming)|malease activity|D-malate hydro-lyase activity|(R)-malate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0050075 GO:0098018 biolink:CellularComponent viral capsid, minor subunit The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits. go-plus.json minor capsomere|minor head protein http://purl.obolibrary.org/obo/GO_0098018 GO:0050076 biolink:MolecularActivity maleate isomerase activity Catalysis of the reaction: maleate = fumarate. RHEA:13169|KEGG_REACTION:R01087|EC:5.2.1.1|MetaCyc:MALEATE-ISOMERASE-RXN go-plus.json maleate cis-trans-isomerase activity http://purl.obolibrary.org/obo/GO_0050076 NCBITaxon:64898 biolink:OrganismalEntity Aquificaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_64898 CL:0000707 biolink:Cell R7 photoreceptor cell go-plus.json R7 cell http://purl.obolibrary.org/obo/CL_0000707 CL:0000708 biolink:Cell leptomeningeal cell Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. go-plus.json leptomemingeal cell http://purl.obolibrary.org/obo/CL_0000708 CL:0000709 biolink:Cell R8 photoreceptor cell go-plus.json R8 cell http://purl.obolibrary.org/obo/CL_0000709 CHEBI:6041 biolink:ChemicalSubstance (+)-isopiperitenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_6041 chebi_ph7_3 CL:0000700 biolink:Cell dopaminergic neuron A neuron that releases dopamine as a neurotransmitter. go-plus.json dopaminergic cell http://purl.obolibrary.org/obo/CL_0000700 CL:0000704 biolink:Cell endothelial tip cell A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. go-plus.json http://purl.obolibrary.org/obo/CL_0000704 CHEBI:6039 biolink:ChemicalSubstance isopimaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_6039 GO:0050080 biolink:MolecularActivity malonyl-CoA decarboxylase activity Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2. MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN|EC:4.1.1.9|Reactome:R-HSA-977317|RHEA:18781 go-plus.json malonyl-CoA carboxy-lyase (acetyl-CoA-forming)|malonyl coenzyme A decarboxylase activity|malonyl-CoA carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0050080 CHEBI:17888 biolink:ChemicalSubstance 6-phospho-beta-D-glucosyl-(1->4)-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17888 GO:0050081 biolink:MolecularActivity maltose-6'-phosphate glucosidase activity Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate. RHEA:20421|EC:3.2.1.122|MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN go-plus.json phospho-alpha-glucosidase activity|maltose-6'-phosphate 6-phosphoglucohydrolase activity http://purl.obolibrary.org/obo/GO_0050081 CHEBI:17889 biolink:ChemicalSubstance isopyridoxal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17889 chebi_ph7_3 CHEBI:17886 biolink:ChemicalSubstance D-tagaturonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17886 chebi_ph7_3 CHEBI:17884 biolink:ChemicalSubstance N(2)-phenylacetyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17884 GO:0050084 biolink:MolecularActivity mannitol-1-phosphatase activity Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate. EC:3.1.3.22|MetaCyc:MANNITOL-1-PHOSPHATASE-RXN|KEGG_REACTION:R02167|RHEA:19537 go-plus.json mannitol-1-phosphate phosphatase activity|D-mannitol-1-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050084 GO:0050085 biolink:MolecularActivity mannitol 2-dehydrogenase (NADP+) activity Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH. MetaCyc:MANNITOL-2-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R00870|RHEA:16765|EC:1.1.1.138 go-plus.json NADP-dependent mannitol dehydrogenase activity|D-mannitol:NADP+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050085 CHEBI:17885 biolink:ChemicalSubstance CDP-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17885 CHEBI:17882 biolink:ChemicalSubstance UDP-N-acetylmuramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17882 GO:0050082 biolink:MolecularActivity maltose phosphorylase activity Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate. RHEA:21116|MetaCyc:MALTOSE-PHOSPHORYLASE-RXN|EC:2.4.1.8 go-plus.json maltose:phosphate 1-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050082 CHEBI:17883 biolink:ChemicalSubstance hydrogen chloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_17883 GO:0050083 biolink:MolecularActivity malyl-CoA lyase activity Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate. MetaCyc:MALYL-COA-LYASE-RXN|RHEA:16629|EC:4.1.3.24 go-plus.json (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)|malyl-coenzyme A lyase activity|(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity http://purl.obolibrary.org/obo/GO_0050083 CHEBI:6032 biolink:ChemicalSubstance isonicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_6032 GO:0050088 biolink:MolecularActivity mannose-6-phosphate 6-reductase activity Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH. KEGG_REACTION:R01817|RHEA:14925|MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN|EC:1.1.1.224 go-plus.json D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity|NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity|NADPH-dependent M6P reductase activity|mannose-6-phosphate reductase activity|6-phosphomannose reductase activity|NADPH-dependent mannose 6-phosphate reductase activity|NADPH-mannose-6-P reductase activity http://purl.obolibrary.org/obo/GO_0050088 CHEBI:42819 biolink:ChemicalSubstance 5-dehydro-4-deoxy-D-glucarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_42819 chebi_ph7_3 CHEBI:17881 biolink:ChemicalSubstance 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17881 GO:0050089 biolink:MolecularActivity mannose isomerase activity Catalysis of the reaction: D-mannose = D-fructose. RHEA:22604|KEGG_REACTION:R00877|EC:5.3.1.7|MetaCyc:MANNOSE-ISOMERASE-RXN go-plus.json D-mannose aldose-ketose-isomerase activity|D-mannose isomerase activity|D-mannose ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0050089 GO:0050086 biolink:MolecularActivity mannitol 2-dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH. EC:1.1.1.67|MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN|RHEA:12084 go-plus.json D-mannitol dehydrogenase activity|D-mannitol:NAD+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050086 GO:0050087 biolink:MolecularActivity mannitol dehydrogenase (cytochrome) activity Catalysis of the reaction: 2 [Fe(III)cytochrome c] + D-mannitol = 2 [Fe(II)cytochrome c] + D-fructose + 2 H+. RHEA:17597|MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.1.2.2 go-plus.json polyol dehydrogenase activity|D-mannitol:ferricytochrome-c 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050087 CL:0000718 biolink:Cell compound eye cone cell go-plus.json cone cell (sensu Endopterygota) http://purl.obolibrary.org/obo/CL_0000718 CL:0000710 biolink:Cell neurecto-epithelial cell Epithelial cells derived from neural plate and neural crest. go-plus.json neuroepithelial cell http://purl.obolibrary.org/obo/CL_0000710 CL:0000711 biolink:Cell cumulus cell Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. go-plus.json http://purl.obolibrary.org/obo/CL_0000711 CL:0000715 biolink:Cell embryonic crystal cell go-plus.json http://purl.obolibrary.org/obo/CL_0000715 CL:0000716 biolink:Cell lymph gland crystal cell go-plus.json http://purl.obolibrary.org/obo/CL_0000716 UBERON:0010425 biolink:AnatomicalEntity internal naris A naris that is located inside the nasal cavity and connects to the pharynx. go-plus.json internal choana|internal nostril|choana|internal nares|choanae http://purl.obolibrary.org/obo/UBERON_0010425 CHEBI:17879 biolink:ChemicalSubstance 4-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17879 chebi_ph7_3 CHEBI:17877 biolink:ChemicalSubstance FADH2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_17877 GO:0050091 biolink:MolecularActivity melilotate 3-monooxygenase activity Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+). EC:1.14.13.4|KEGG_REACTION:R03369|MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN|RHEA:17669 go-plus.json 3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)|melilotate hydroxylase activity|2-hydroxyphenylpropionic hydroxylase activity|melilotic hydroxylase activity|2-hydroxyphenylpropionate hydroxylase activity http://purl.obolibrary.org/obo/GO_0050091 GO:0050092 biolink:MolecularActivity meso-tartrate dehydrogenase activity Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH. EC:1.3.1.7|RHEA:18553|MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN|KEGG_REACTION:R02544 go-plus.json meso-tartrate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050092 CHEBI:17878 biolink:ChemicalSubstance 2-hydroxycyclohexan-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17878 chebi_ph7_3 UBERON:0010427 biolink:AnatomicalEntity ciliary processes The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens. go-plus.json processus ciliares|ciliary process|ciliary processes set|ciliary processes|set of ciliary processes|processus ciliares http://purl.obolibrary.org/obo/UBERON_0010427 CHEBI:17875 biolink:ChemicalSubstance quercetin 3,3'-bissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17875 GO:0050090 biolink:MolecularActivity mannuronate reductase activity Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+. MetaCyc:MANNURONATE-REDUCTASE-RXN|EC:1.1.1.131 go-plus.json D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))|mannonate dehydrogenase (NAD(P)+)|mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity|mannonate dehydrogenase activity|D-mannonate:NAD(P)+ 6-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050090 UBERON:0010428 biolink:AnatomicalEntity flat bone A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow. go-plus.json os planum http://purl.obolibrary.org/obo/UBERON_0010428 CHEBI:17876 biolink:ChemicalSubstance rifamycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_17876 GO:0050095 biolink:MolecularActivity methionine decarboxylase activity Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2). RHEA:17757|EC:4.1.1.57|KEGG_REACTION:R00656|MetaCyc:METHIONINE-DECARBOXYLASE-RXN go-plus.json L-methionine carboxy-lyase (3-methylthiopropanamine-forming)|L-methionine carboxy-lyase activity|L-methionine decarboxylase activity http://purl.obolibrary.org/obo/GO_0050095 GO:0050096 biolink:MolecularActivity methylaspartate ammonia-lyase activity Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+). KEGG_REACTION:R03696|EC:4.3.1.2|MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN|RHEA:12829 go-plus.json beta-methylaspartase activity|L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)|3-methylaspartase activity|L-threo-3-methylaspartate ammonia-lyase activity http://purl.obolibrary.org/obo/GO_0050096 CHEBI:17874 biolink:ChemicalSubstance dihydrozeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17874 chebi_ph7_3 GO:0050093 biolink:MolecularActivity methanol dehydrogenase activity Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH. MetaCyc:METHANOL-DEHYDROGENASE-RXN|RHEA:19401|EC:1.1.1.244|KEGG_REACTION:R00605 go-plus.json methanol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050093 CHEBI:17871 biolink:ChemicalSubstance 3-hydroxypropanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17871 chebi_ph7_3 GO:0050094 biolink:MolecularActivity methionine-glyoxylate transaminase activity Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine. MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN|EC:2.6.1.73|KEGG_REACTION:R00652|RHEA:22884 go-plus.json MGAT activity|L-methionine:glyoxylate aminotransferase activity|methionine-glyoxylate aminotransferase activity http://purl.obolibrary.org/obo/GO_0050094 CHEBI:17872 biolink:ChemicalSubstance 2-oxo-2H-pyran-4,6-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17872 GO:0050099 biolink:MolecularActivity methylglutamate dehydrogenase activity Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde. RHEA:22572|KEGG_REACTION:R00609|EC:1.5.99.5|MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN go-plus.json N-methylglutamate dehydrogenase activity|N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)|N-methyl-L-glutamate:acceptor oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0050099 GO:0050097 biolink:MolecularActivity methylaspartate mutase activity Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate. KEGG_REACTION:R00262|MetaCyc:METHYLASPARTATE-MUTASE-RXN|EC:5.4.99.1|RHEA:12857 go-plus.json glutamic mutase activity|glutamate isomerase activity|beta-methylaspartate-glutamate mutase activity|glutamate mutase activity|L-threo-3-methylaspartate carboxy-aminomethylmutase activity|methylaspartic acid mutase activity|glutamic isomerase activity|b-methylaspartate-glutamate mutase activity|glutamic acid isomerase activity|glutamic acid mutase activity http://purl.obolibrary.org/obo/GO_0050097 GO:0050098 biolink:MolecularActivity methylguanidinase activity Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea. RHEA:11764|MetaCyc:METHYLGUANIDINASE-RXN|EC:3.5.3.16|KEGG_REACTION:R01589 go-plus.json methylguanidine hydrolase activity|methylguanidine amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0050098 GO:0001015 biolink:BiologicalProcess snoRNA transcription by RNA polymerase II The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. go-plus.json snoRNA transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0001015 GO:0001016 biolink:MolecularActivity RNA polymerase III transcription regulatory region sequence-specific DNA binding Binding to a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. go-plus.json RNA polymerase III regulatory region DNA binding http://purl.obolibrary.org/obo/GO_0001016 GO:0001017 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001017 GO:0001018 biolink:MolecularActivity mitochondrial promoter sequence-specific DNA binding Binding to a DNA region that controls the transcription of the mitochondrial DNA. go-plus.json mitochondrial RNA polymerase core promoter sequence-specific DNA binding|LSPas binding|mitochondrial proximal promoter sequence-specific DNA binding|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding|mitochondrial heavy strand promoter sense binding|HSPas binding|mitochondrial heavy strand promoter anti-sense binding|HSPs binding|LSPs binding|mitochondrial RNA polymerase regulatory region DNA binding|mitochondrial RNA polymerase regulatory region sequence-specific DNA binding|mitochondrial light strand promoter sense binding|LSP coding strand binding|LSP non-coding strand binding|mitochondrial light strand promoter anti-sense binding|HSP coding strand binding|HSP non-coding strand binding http://purl.obolibrary.org/obo/GO_0001018 GO:0001011 biolink:MolecularActivity obsolete transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting OBSOLETE. Binding to a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC). go-plus.json sequence-specific DNA binding RNA polymerase recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001011 GO:0001012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001012 GO:0001013 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001013 GO:0001014 biolink:BiologicalProcess snoRNA transcription by RNA polymerase III The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter. go-plus.json snoRNA transcription from a type 2 RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_0001014 CHEBI:134309 biolink:ChemicalSubstance 4'-O-methylxanthohumol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134309 chebi_ph7_3 GO:0039629 biolink:CellularComponent T=219 icosahedral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0039629 GO:0001010 biolink:MolecularActivity RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions. go-plus.json sequence-specific DNA binding transcription factor recruiting transcription factor activity|transcription factor activity, sequence-specific DNA-binding transcription factor recruiting|transcription factor activity, sequence-specific DNA binding transcription factor recruiting http://purl.obolibrary.org/obo/GO_0001010 CHEBI:134308 biolink:ChemicalSubstance xanthogalenol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134308 chebi_ph7_3 GO:0015656 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015656 GO:0039623 biolink:CellularComponent T=25 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres. VZ:810 go-plus.json http://purl.obolibrary.org/obo/GO_0039623 GO:0039624 biolink:CellularComponent viral outer capsid The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions. go-plus.json outer capsid http://purl.obolibrary.org/obo/GO_0039624 CHEBI:134302 biolink:ChemicalSubstance desmethylxanthohumol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134302 chebi_ph7_3 GO:0015657 biolink:MolecularActivity branched-chain amino acid:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in). go-plus.json http://purl.obolibrary.org/obo/GO_0015657 GO:0039621 biolink:CellularComponent T=13 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres. VZ:260 go-plus.json http://purl.obolibrary.org/obo/GO_0039621 GO:0015658 biolink:MolecularActivity branched-chain amino acid transmembrane transporter activity Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. Reactome:R-HSA-9672770 go-plus.json branched-chain aliphatic amino acid transmembrane transporter activity|leucine/valine/isoleucine permease activity|branched-chain aliphatic amino acid transporter activity|valine/tyrosine/tryptophan permease activity http://purl.obolibrary.org/obo/GO_0015658 GO:0039622 biolink:CellularComponent T=16 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres. VZ:807 go-plus.json http://purl.obolibrary.org/obo/GO_0039622 GO:0015659 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015659 GO:0039627 biolink:CellularComponent T=147 icosahedral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0039627 GO:0015652 biolink:MolecularActivity quaternary ammonium group:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in). go-plus.json quaternary ammonium group:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015652 GO:0039628 biolink:CellularComponent T=169 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins. go-plus.json T=169 icosahedral capsid http://purl.obolibrary.org/obo/GO_0039628 GO:0015653 biolink:MolecularActivity glycine betaine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in). go-plus.json glycine betaine:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015653 GO:0039625 biolink:CellularComponent viral inner capsid The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions. go-plus.json inner capsid http://purl.obolibrary.org/obo/GO_0039625 GO:0015654 biolink:MolecularActivity tellurite transmembrane transporter activity Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals. go-plus.json tellurite uptake transmembrane transporter activity|tellurite-resistance uptake permease activity|tellurite-resistance uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015654 GO:0015655 biolink:MolecularActivity alanine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in). RHEA:29283 go-plus.json sodium:alanine symporter activity http://purl.obolibrary.org/obo/GO_0015655 GO:0039626 biolink:CellularComponent viral intermediate capsid The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions. go-plus.json intermediate capsid http://purl.obolibrary.org/obo/GO_0039626 CHEBI:6099 biolink:ChemicalSubstance kaempferide go-plus.json http://purl.obolibrary.org/obo/CHEBI_6099 GO:0015650 biolink:MolecularActivity lactate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in). go-plus.json lactate permease|lactate:proton porter activity|lactate:hydrogen porter activity|lactate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015650 CHEBI:52157 biolink:ChemicalSubstance organic heteroheptacyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_52157 GO:0015651 biolink:MolecularActivity quaternary ammonium group transmembrane transporter activity Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. go-plus.json quaternary ammonium compound transporter activity|quaternary amine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015651 GO:0001019 biolink:MolecularActivity plastid promoter transcription regulatory region sequence-specific DNA binding Binding to a DNA region that controls transcription by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. go-plus.json http://purl.obolibrary.org/obo/GO_0001019 GO:0039620 biolink:CellularComponent T=7 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres. VZ:804 go-plus.json http://purl.obolibrary.org/obo/GO_0039620 GO:0001026 biolink:MolecularActivity obsolete TFIIIB-type transcription factor activity OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. go-plus.json RNA polymerase III recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001026 GO:0001027 biolink:MolecularActivity obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. go-plus.json RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001027 GO:0001028 biolink:MolecularActivity obsolete RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. go-plus.json RNA polymerase III type 2 promoter polymerase recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001028 GO:0001029 biolink:MolecularActivity obsolete RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. go-plus.json RNA polymerase III type 3 promoter polymerase recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001029 GO:0001022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001022 GO:0001023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001023 GO:0001024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001024 GO:0001025 biolink:MolecularActivity RNA polymerase III general transcription initiation factor binding Binding to an RNA polymerase III transcription factor, a protein required to initiate or regulate transcription by RNA polymerase III. go-plus.json RNA polymerase III transcription factor binding http://purl.obolibrary.org/obo/GO_0001025 GO:0001020 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001020 GO:0039618 biolink:CellularComponent T=pseudo3 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres. VZ:809 go-plus.json http://purl.obolibrary.org/obo/GO_0039618 GO:0001021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001021 GO:0039619 biolink:CellularComponent T=4 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres. VZ:808 go-plus.json http://purl.obolibrary.org/obo/GO_0039619 OIO:consider biolink:OntologyClass consider go-plus.json http://www.geneontology.org/formats/oboInOwl#consider GO:0015667 biolink:MolecularActivity site-specific DNA-methyltransferase (cytosine-N4-specific) activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine. RHEA:16857|MetaCyc:2.1.1.113-RXN|EC:2.1.1.113 go-plus.json N4-cytosine-specific DNA methylase activity|S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity|S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity|N(4)-cytosine-specific DNA methylase activity|modification methylase activity|restriction-modification system activity|m4C-forming MTase activity|DNA[cytosine-N4]methyltransferase activity http://purl.obolibrary.org/obo/GO_0015667 GO:0039612 biolink:BiologicalProcess modulation by virus of host protein phosphorylation Any viral process that modulates the frequency, rate or extent of phosphorylation of viral or host proteins in a host. go-plus.json http://purl.obolibrary.org/obo/GO_0039612 GO:0015668 biolink:MolecularActivity type III site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites. EC:3.1.21.5|MetaCyc:3.1.21.5-RXN go-plus.json type III restriction enzyme activity http://purl.obolibrary.org/obo/GO_0015668 GO:0039613 biolink:BiologicalProcess suppression by virus of host protein phosphorylation Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of phosphorylation of viral or host proteins in a host. go-plus.json viral inhibition of host protein phosphorylation http://purl.obolibrary.org/obo/GO_0039613 GO:0015669 biolink:BiologicalProcess gas transport The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015669 goslim_pir GO:0039611 biolink:BiologicalProcess suppression by virus of host translation initiation factor activity Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor. go-plus.json inhibition of activity of host translation initiation factor|Inhibition of host translation factors by virus|inactivation of eIF2 activity|suppression by virus of host EIF-4E activity http://purl.obolibrary.org/obo/GO_0039611 CHEBI:134311 biolink:ChemicalSubstance D-altritol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134311 chebi_ph7_3 GO:0039616 biolink:CellularComponent T=2 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers. VZ:838 go-plus.json http://purl.obolibrary.org/obo/GO_0039616 GO:0015663 biolink:MolecularActivity nicotinamide mononucleotide transmembrane transporter activity Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP. go-plus.json nicotinamide ribonucleotide transmembrane transporter activity|nicotinamide mononucleotide permease activity http://purl.obolibrary.org/obo/GO_0015663 CHEBI:134316 biolink:ChemicalSubstance 2-acylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134316 GO:0039617 biolink:CellularComponent T=3 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres. VZ:806 go-plus.json http://purl.obolibrary.org/obo/GO_0039617 GO:0015664 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015664 GO:0039614 biolink:BiologicalProcess induction by virus of host protein phosphorylation Any process in which a virus activates or increases the frequency, rate or extent of phosphorylation of viral or host proteins in a host. go-plus.json http://purl.obolibrary.org/obo/GO_0039614 GO:0015665 biolink:MolecularActivity alcohol transmembrane transporter activity Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0015665 GO:0039615 biolink:CellularComponent T=1 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres. VZ:1057 go-plus.json http://purl.obolibrary.org/obo/GO_0039615 GO:0015666 biolink:MolecularActivity restriction endodeoxyribonuclease activity Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. go-plus.json restriction endonuclease activity|restriction enzyme activity http://purl.obolibrary.org/obo/GO_0015666 CHEBI:52144 biolink:ChemicalSubstance flavonol 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52144 chebi_ph7_3 GO:0015660 biolink:MolecularActivity formate efflux transmembrane transporter activity Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane. go-plus.json formate efflux permease activity http://purl.obolibrary.org/obo/GO_0015660 GO:0015661 biolink:MolecularActivity L-lysine efflux transmembrane transporter activity Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane. go-plus.json L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity|L-lysine exporter activity http://purl.obolibrary.org/obo/GO_0015661 GO:0015662 biolink:MolecularActivity P-type ion transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate. Reactome:R-HSA-429157 go-plus.json P-type ATPase activity|ion transmembrane transporter activity, phosphorylative mechanism|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism http://purl.obolibrary.org/obo/GO_0015662 CHEBI:52142 biolink:ChemicalSubstance flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52142 chebi_ph7_3 CHEBI:52143 biolink:ChemicalSubstance flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52143 chebi_ph7_3 PO:0004545 biolink:OntologyClass shoot-borne shoot system A shoot system that is initiated from a shoot. go-plus.json sucker (broad)|turion (broad)|シュート由来苗条系 (Japanese, exact)|sistema de epiblasto (epiblastema) que nace en el epiblasto (epiblastema) (Spanish, exact)|branch (related) http://purl.obolibrary.org/obo/PO_0004545 CHEBI:52138 biolink:ChemicalSubstance 4-O-phosphohygromycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_52138 CHEBI:27177 biolink:ChemicalSubstance L-tyrosine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_27177 GO:0039607 biolink:BiologicalProcess obsolete proteolysis by virus of host translation initiation factor OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds. go-plus.json cleavage of host translation initiation factor by virus|proteolytic cleavage by virus of host translation initiation factor|suppression by virus of host translation initiation factor activity by proteolysis|cleavage of host translation initiation factor by viral protease http://purl.obolibrary.org/obo/GO_0039607 GO:0039608 biolink:BiologicalProcess obsolete suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation OBSOLETE. Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein. go-plus.json http://purl.obolibrary.org/obo/GO_0039608 GO:0015638 biolink:MolecularActivity microcin transmembrane transporter activity Enables the transfer of a microcin from one side of a membrane to the other. go-plus.json microcin uptake permease activity http://purl.obolibrary.org/obo/GO_0015638 CHEBI:27173 biolink:ChemicalSubstance typhasterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27173 chebi_ph7_3 GO:0015639 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015639 CHEBI:27175 biolink:ChemicalSubstance tyramines go-plus.json http://purl.obolibrary.org/obo/CHEBI_27175 GO:0015634 biolink:MolecularActivity obsolete lipopolysaccharide exporter activity OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. go-plus.json LPS exporter activity http://purl.obolibrary.org/obo/GO_0015634 GO:0039601 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0039601 GO:0015635 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015635 GO:0039602 biolink:BiologicalProcess suppression by virus of host transcription initiation from RNA polymerase II promoter Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. VZ:904 go-plus.json suppression by virus of host DNA-dependent transcription, initiation|inhibition of host transcription initiation by virus http://purl.obolibrary.org/obo/GO_0039602 GO:0015636 biolink:MolecularActivity short-chain fatty acid transmembrane transporter activity Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6. go-plus.json short-chain fatty acid transporter activity|short-chain fatty acid uptake transporter activity http://purl.obolibrary.org/obo/GO_0015636 GO:0039600 biolink:BiologicalProcess induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process The process in which a virus increases the frequency, rate or extent of the breakdown of host nuclear-transcribed mRNAs that begins with endonucleolytic cleavage (by either a host or a viral RNAse) to generate unprotected ends. go-plus.json induction by virus of host endonucleolytic cleavage-dependent mRNA decay|induction by virus of host nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay http://purl.obolibrary.org/obo/GO_0039600 GO:0015637 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015637 GO:0015630 biolink:CellularComponent microtubule cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0015630 goslim_aspergillus GO:0039605 biolink:MolecularActivity obsolete TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. go-plus.json http://purl.obolibrary.org/obo/GO_0039605 GO:0039606 biolink:BiologicalProcess suppression by virus of host translation initiation Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0039606 GO:0015631 biolink:MolecularActivity tubulin binding Binding to monomeric or multimeric forms of tubulin, including microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0015631 GO:0039603 biolink:MolecularActivity obsolete TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. go-plus.json http://purl.obolibrary.org/obo/GO_0039603 GO:0015632 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015632 GO:0039604 biolink:BiologicalProcess suppression by virus of host translation Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA. VZ:1579 go-plus.json viral inhibition of cellular protein synthesis|host translation shutoff by virus|viral shutoff of host protein synthesis http://purl.obolibrary.org/obo/GO_0039604 GO:0015633 biolink:MolecularActivity ABC-type zinc transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in). EC:7.2.2.20|RHEA:29795 go-plus.json zinc transporting ATPase activity|zinc porter activity|ATP-dependent zinc transmembrane transporter activity|ATPase-coupled zinc transmembrane transporter activity|zinc-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0015633 CHEBI:52135 biolink:ChemicalSubstance steroidal acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52135 CHEBI:52136 biolink:ChemicalSubstance glufosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52136 CHEBI:52130 biolink:ChemicalSubstance benzofuropyranochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_52130 GO:0001004 biolink:MolecularActivity obsolete RNA polymerase III transcription regulator recruiting activity OBSOLETE. Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB. go-plus.json RNA polymerase III assembly factor activity, TFIIIB recruiting|TFIIIA activity|RNA polymerase III transcription factor recruiting activity|RNA polymerase III type 3 promoter TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting|RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity|SNAPc-type activity|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III assembly factor activity|RNA polymerase III promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III type 3 promoter TFIIIB recruiting|type 3 RNA polymerase III promoter recognition|transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting|transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting|type 2 RNA polymerase III promoter recognition|transcription factor activity, RNA polymerase III type 1 promoter TFIIIB|TFIIIC-type activity http://purl.obolibrary.org/obo/GO_0001004 PO:0004535 biolink:OntologyClass fruit placenta A portion of placenta tissue (PO:0025078) that is part of a fruit (PO:0009001) and to which seeds (PO:0009010) are attached. go-plus.json placenta del fruto (Spanish, exact)|果実の胎座 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0004535 GO:0001005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001005 GO:0001006 biolink:MolecularActivity RNA polymerase III type 3 promoter sequence-specific DNA binding Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae. go-plus.json RNA polymerase III type 3 promoter DNA binding http://purl.obolibrary.org/obo/GO_0001006 GO:0001007 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase III transcription factor binding OBSOLETE. Binding to an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json RNA polymerase III transcription factor binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001007 GO:0001000 biolink:MolecularActivity bacterial-type RNA polymerase core enzyme binding Binding to a bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit. go-plus.json eubacterial-type RNA polymerase core enzyme binding http://purl.obolibrary.org/obo/GO_0001000 GO:0001001 biolink:MolecularActivity mitochondrial single-subunit type RNA polymerase binding Binding to a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6. go-plus.json http://purl.obolibrary.org/obo/GO_0001001 CHEBI:52127 biolink:ChemicalSubstance (-)-glyceollin II go-plus.json http://purl.obolibrary.org/obo/CHEBI_52127 chebi_ph7_3 GO:0001002 biolink:MolecularActivity RNA polymerase III type 1 promoter sequence-specific DNA binding Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition. go-plus.json RNA polymerase III type 1 promoter DNA binding http://purl.obolibrary.org/obo/GO_0001002 GO:0001003 biolink:MolecularActivity RNA polymerase III type 2 promoter sequence-specific DNA binding Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs. go-plus.json RNA polymerase III type 2 promoter DNA binding http://purl.obolibrary.org/obo/GO_0001003 GO:0015649 biolink:MolecularActivity 2-keto-3-deoxygluconate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in). go-plus.json 2-keto-3-deoxygluconate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0015649 GO:0015645 biolink:MolecularActivity fatty acid ligase activity Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP. go-plus.json fatty acid CoA ligase activity|fatty-acid ligase activity|fatty acyl-coenzyme A synthetase activity http://purl.obolibrary.org/obo/GO_0015645 CHEBI:27191 biolink:ChemicalSubstance undecaprenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_27191 GO:0015646 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015646 GO:0015647 biolink:MolecularActivity peptidoglycan transmembrane transporter activity Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other. go-plus.json murein transporter activity http://purl.obolibrary.org/obo/GO_0015647 CHEBI:27193 biolink:ChemicalSubstance undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27193 GO:0015648 biolink:MolecularActivity lipid-linked peptidoglycan transporter activity Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells. go-plus.json lipid-linked murein transporter activity http://purl.obolibrary.org/obo/GO_0015648 CHEBI:27194 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetylmuramoyl peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27194 CHEBI:76151 biolink:ChemicalSubstance (8Z,11Z,14Z)-heptadecatrienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_76151 chebi_ph7_3 GO:0015641 biolink:MolecularActivity obsolete lipoprotein toxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json lipoprotein toxin http://purl.obolibrary.org/obo/GO_0015641 CHEBI:76152 biolink:ChemicalSubstance (8Z,11Z,14Z)-heptadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76152 chebi_ph7_3 GO:0015642 biolink:MolecularActivity obsolete bacteriolytic toxin activity OBSOLETE. Acts as to cause lysis of bacterial cells. go-plus.json bacteriolytic toxin activity http://purl.obolibrary.org/obo/GO_0015642 GO:0015643 biolink:MolecularActivity toxic substance binding Binding to a toxic substance, a poisonous substance that causes damage to biological systems. go-plus.json antitoxin activity|lipoprotein antitoxin http://purl.obolibrary.org/obo/GO_0015643 GO:0015644 biolink:MolecularActivity obsolete lipoprotein antitoxin OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it. go-plus.json lipoprotein antitoxin http://purl.obolibrary.org/obo/GO_0015644 CHEBI:76150 biolink:ChemicalSubstance (R)-2-hydroxy-alpha-linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76150 chebi_ph7_3 GO:0015640 biolink:MolecularActivity peptidoglycan peptide transmembrane transporter activity Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains. go-plus.json muropeptide transporter activity|murein peptide transporter activity http://purl.obolibrary.org/obo/GO_0015640 GO:0001008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001008 CHEBI:76159 biolink:ChemicalSubstance tetracenomycin F2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76159 GO:0001009 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001009 GO:1990398 biolink:CellularComponent Cus cation efflux complex Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth. go-plus.json silver efflux system|Cus cation efflux system|silver efflux complex|copper efflux complex|copper efflux system http://purl.obolibrary.org/obo/GO_1990398 GO:1990399 biolink:BiologicalProcess epithelium regeneration The regrowth of lost or destroyed epithelium. go-plus.json regeneration of epithelium http://purl.obolibrary.org/obo/GO_1990399 GO:1990394 biolink:BiologicalProcess cellular response to cell wall damage Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_1990394 GO:1990395 biolink:BiologicalProcess meiotic spindle pole body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_1990395 GO:1990396 biolink:BiologicalProcess single-strand break repair via homologous recombination The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990396 GO:1990397 biolink:BiologicalProcess queuosine salvage Any process which produces queuosine from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_1990397 GO:1990390 biolink:BiologicalProcess protein K33-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_1990390 GO:1990391 biolink:CellularComponent DNA repair complex A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. go-plus.json WHY1 complex|DNA damage repair complex http://purl.obolibrary.org/obo/GO_1990391 GO:1990392 biolink:CellularComponent EFF-1 complex A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer. go-plus.json http://purl.obolibrary.org/obo/GO_1990392 GO:1990393 biolink:CellularComponent 3M complex A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity. go-plus.json http://purl.obolibrary.org/obo/GO_1990393 GO:0015616 biolink:MolecularActivity DNA translocase activity Generation of movement along a single- or double-stranded DNA molecule, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0015616 GO:0015617 biolink:MolecularActivity obsolete pilin/fimbrilin exporter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json pilin/fimbrilin exporter activity http://purl.obolibrary.org/obo/GO_0015617 CHEBI:27153 biolink:ChemicalSubstance monoatomic trication go-plus.json http://purl.obolibrary.org/obo/CHEBI_27153 chebi_ph7_3 GO:0015618 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015618 GO:0015619 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015619 GO:0015612 biolink:MolecularActivity ABC-type L-arabinose transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in). MetaCyc:ABC-2-RXN|EC:7.5.2.13|EC:7.5.2.12|RHEA:30007 go-plus.json L-arabinose porter activity|L-arabinose-importing ATPase activity http://purl.obolibrary.org/obo/GO_0015612 GO:0015613 biolink:MolecularActivity obsolete galactose/glucose (methylgalactoside) porter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json galactose/glucose (methylgalactoside) porter activity http://purl.obolibrary.org/obo/GO_0015613 GO:0015614 biolink:MolecularActivity ABC-type D-xylose transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in). RHEA:29899|EC:7.5.2.10 go-plus.json ATPase-coupled D-xylose transmembrane transporter activity|D-xylose-importing ATPase activity|D-xylose porter activity http://purl.obolibrary.org/obo/GO_0015614 GO:0015615 biolink:MolecularActivity D-allose-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in). go-plus.json D-allose porter activity http://purl.obolibrary.org/obo/GO_0015615 GO:0015610 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015610 GO:0015611 biolink:MolecularActivity ABC-type D-ribose transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in). EC:7.5.2.8|RHEA:29903|MetaCyc:ABC-28-RXN go-plus.json D-ribose-importing ATPase activity|D-ribose porter activity http://purl.obolibrary.org/obo/GO_0015611 CHEBI:76161 biolink:ChemicalSubstance (R)-2-hydroperoxy-alpha-linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76161 chebi_ph7_3 CHEBI:76166 biolink:ChemicalSubstance 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76166 chebi_ph7_3 CHEBI:76168 biolink:ChemicalSubstance 1-alkyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76168 chebi_ph7_3 GO:0015627 biolink:CellularComponent type II protein secretion system complex A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex. go-plus.json main terminal branch|MTB|general secretion pathway-associated complex|T2SS-associated complexes|Sec-dependent secretion system-associated complex http://purl.obolibrary.org/obo/GO_0015627 CHEBI:27162 biolink:ChemicalSubstance tryptamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_27162 GO:0015628 biolink:BiologicalProcess protein secretion by the type II secretion system The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways. go-plus.json protein secretion by the T2S|protein secretion by the type II protein secretion system|protein secretion by the general secretory pathway|protein secretion by the general secretion pathway|protein secretion by the T2SS|type II protein secretion system http://purl.obolibrary.org/obo/GO_0015628 GO:0015629 biolink:CellularComponent actin cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0015629 goslim_aspergillus CHEBI:27164 biolink:ChemicalSubstance tryptophan derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_27164 GO:0015623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015623 UBERON:0009503 biolink:AnatomicalEntity mesenchyme of hindgut Mesenchyme that is part of a developing hindgut. go-plus.json hindgut associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0009503 GO:0015624 biolink:MolecularActivity ABC-type ferric-enterobactin transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in). MetaCyc:ABC-10-RXN|EC:7.2.2.17|RHEA:58492 go-plus.json ferric-enterobactin-transporting ATPase activity|ferric-enterobactin ABC transporter|ferric-enterobactin porter activity|ATP-dependent ferric-enterobactin transmembrane transporter activity|ATPase-coupled ferric-enterobactin transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015624 CHEBI:76170 biolink:ChemicalSubstance olefinic phospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76170 GO:0015625 biolink:MolecularActivity ABC-type ferric hydroxamate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in). MetaCyc:3.6.3.34-RXN|MetaCyc:ABC-11-RXN|MetaCyc:ABC-9-RXN|EC:7.2.2.16 go-plus.json ferric-hydroxamate porter activity|ATPase-coupled ferric-hydroxamate transmembrane transporter activity|ATP-dependent iron-chelate transporter activity|ATPase-coupled iron-chelate transporter activity|ferric-hydroxamate-transporting ATPase activity|iron-chelate-transporting ATPase activity|ferric-hydroxamate transmembrane transporter activity|ferric-hydroxamate ABC transporter|ATP-dependent ferric-hydroxamate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015625 CHEBI:27171 biolink:ChemicalSubstance organic heterobicyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_27171 UBERON:0009505 biolink:AnatomicalEntity mesenchyme of trachea Mesenchyme that is part of a developing trachea. go-plus.json trachea associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0009505 GO:0015626 biolink:MolecularActivity L-diaminopimelate transmembrane transporter activity Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid. go-plus.json L-diaminopimelate transporter activity|cystine/diaminopimelate porter activity http://purl.obolibrary.org/obo/GO_0015626 UBERON:0009506 biolink:AnatomicalEntity mesenchyme of middle ear Mesenchyme that is part of a developing middle ear. go-plus.json otic mesenchyme|middle ear associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0009506 GO:0015620 biolink:MolecularActivity ferric-enterobactin transmembrane transporter activity Enables the transfer of ferric-enterobactin from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015620 CHEBI:76171 biolink:ChemicalSubstance 1-acyl-2-(10-methylenealkanoyl)-sn-3-glycerophospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76171 chebi_ph7_3 GO:0015621 biolink:MolecularActivity ferric triacetylfusarinine C transmembrane transporter activity Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015621 GO:0015622 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015622 CHEBI:76177 biolink:ChemicalSubstance (2R)-2-hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76177 chebi_ph7_3 CHEBI:76176 biolink:ChemicalSubstance 2-hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76176 chebi_ph7_3 UBERON:0009500 biolink:AnatomicalEntity periotic mesenchyme Anatomical region that surrounds the otic vesicle. go-plus.json otocyst mesenchyme|periotic region|otocyst associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0009500 CHEBI:76179 biolink:ChemicalSubstance O-(S-acylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_76179 chebi_ph7_3 CHEBI:124959 biolink:ChemicalSubstance (2S)-2-amino-5-[[amino(methylimino)methyl]amino]pentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_124959 UBERON:0009501 biolink:AnatomicalEntity mesenchyme of fronto-nasal process The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head go-plus.json naso-frontal mesenchyme|frontonasal mesenchyme http://purl.obolibrary.org/obo/UBERON_0009501 GO:0050004 biolink:MolecularActivity isoflavone 7-O-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside. RHEA:56344|EC:2.4.1.170|MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN go-plus.json UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-flavonoid 7-O-glucosyltransferase activity|UDPglucose:isoflavone 7-O-glucosyltransferase activity|uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity|UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050004 GO:0050005 biolink:MolecularActivity isohexenylglutaconyl-CoA hydratase activity Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O. RHEA:24144|KEGG_REACTION:R03493|MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN|EC:4.2.1.57|UM-BBD_reactionID:r1167 go-plus.json beta-isohexenylglutaconyl-CoA-hydratase activity|isohexenylglutaconyl coenzyme A hydratase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]|3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity http://purl.obolibrary.org/obo/GO_0050005 GO:0050002 biolink:MolecularActivity D-proline reductase (dithiol) activity Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline. EC:1.21.4.1|MetaCyc:1.21.4.1-RXN|RHEA:12737 go-plus.json 5-aminopentanoate:lipoate oxidoreductase (cyclizing) http://purl.obolibrary.org/obo/GO_0050002 GO:0050003 biolink:MolecularActivity deoxycytidylate C-methyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate. KEGG_REACTION:R01670|EC:2.1.1.54|MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN|RHEA:11568 go-plus.json deoxycytidylate methyltransferase activity|5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity|dCMP methyltransferase activity http://purl.obolibrary.org/obo/GO_0050003 GO:0050008 biolink:MolecularActivity isopiperitenone delta-isomerase activity Catalysis of the reaction: isopiperitenone = piperitenone. EC:5.3.3.11|KEGG_REACTION:R03782|MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN|RHEA:21516 go-plus.json isopiperitenone D-isomerase activity|isopiperitenone delta8-delta4-isomerase activity http://purl.obolibrary.org/obo/GO_0050008 CHEBI:27137 biolink:ChemicalSubstance triose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27137 GO:0050009 biolink:MolecularActivity isopropanol dehydrogenase (NADP+) activity Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH. EC:1.1.1.80|KEGG_REACTION:R01550|RHEA:21792|MetaCyc:ISOPROPANOL-DEHYDROGENASE-NADP+-RXN go-plus.json propan-2-ol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050009 GO:0050006 biolink:MolecularActivity isomaltulose synthase activity Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose. RHEA:24032|MetaCyc:ISOMALTULOSE-SYNTHASE-RXN|EC:5.4.99.11 go-plus.json trehalulose synthase activity|isomaltulose synthetase activity|sucrose alpha-glucosyltransferase activity|sucrose glucosylmutase activity http://purl.obolibrary.org/obo/GO_0050006 GO:0050007 biolink:MolecularActivity isonocardicin synthase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A. RHEA:19845|KEGG_REACTION:R03072|MetaCyc:ISONOCARDICIN-SYNTHASE-RXN|EC:2.5.1.38 go-plus.json nocardicin aminocarboxypropyltransferase activity|S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity http://purl.obolibrary.org/obo/GO_0050007 CL:0000787 biolink:Cell memory B cell A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. go-plus.json memory B-lymphocyte|memory B lymphocyte|memory B-cell http://purl.obolibrary.org/obo/CL_0000787 CL:0000788 biolink:Cell naive B cell A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. go-plus.json naive B-cell|naive B-lymphocyte|naive B lymphocyte http://purl.obolibrary.org/obo/CL_0000788 CHEBI:27134 biolink:ChemicalSubstance trimethylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27134 CL:0000789 biolink:Cell alpha-beta T cell A T cell that expresses an alpha-beta T cell receptor complex. go-plus.json alpha-beta T lymphocyte|alpha-beta T-cell|alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/CL_0000789 CHEBI:27135 biolink:ChemicalSubstance trinitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27135 CHEBI:27136 biolink:ChemicalSubstance triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27136 NCBITaxon:653685 biolink:OrganismalEntity Bacillus subtilis group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_653685 CHEBI:76180 biolink:ChemicalSubstance arachidonoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76180 chebi_ph7_3 CL:0000780 biolink:Cell multinuclear odontoclast A specialized multinuclear osteoclast associated with the absorption and removal of cementum. go-plus.json multinucleated odontoclast http://purl.obolibrary.org/obo/CL_0000780 CL:0000781 biolink:Cell mononuclear odontoclast A specialized mononuclear osteoclast associated with the absorption and removal of cementum. go-plus.json http://purl.obolibrary.org/obo/CL_0000781 CL:0000782 biolink:Cell myeloid dendritic cell A dendritic cell of the myeloid lineage. go-plus.json veiled cell|CD11c+CD123- DC|interdigitating cell|mDC http://purl.obolibrary.org/obo/CL_0000782 CHEBI:76184 biolink:ChemicalSubstance alpha-linolenoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76184 chebi_ph7_3 CL:0000784 biolink:Cell plasmacytoid dendritic cell A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. go-plus.json plasmacytoid T cell|T-associated plasma cell|IPC|interferon-producing cell|plasmacytoid monocyte|DC2|type 2 DC|lymphoid dendritic cell|pDC http://purl.obolibrary.org/obo/CL_0000784 CHEBI:76185 biolink:ChemicalSubstance stearidonoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76185 chebi_ph7_3 CL:0000785 biolink:Cell mature B cell A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. go-plus.json mature B-cell|mature B-lymphocyte|mature B lymphocyte http://purl.obolibrary.org/obo/CL_0000785 CL:0000786 biolink:Cell plasma cell A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. go-plus.json plasmacyte|effector B cell|plasma B cell|plasmocyte|effector B-cell|plasma B-cell http://purl.obolibrary.org/obo/CL_0000786 CHEBI:76189 biolink:ChemicalSubstance timnodonoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76189 chebi_ph7_3 CHEBI:76186 biolink:ChemicalSubstance linoleoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76186 chebi_ph7_3 CHEBI:76187 biolink:ChemicalSubstance gamma-linolenoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76187 chebi_ph7_3 GO:0050000 biolink:BiologicalProcess chromosome localization Any process in which a chromosome is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of chromosome position|chromosome localisation|establishment and maintenance of chromosome localization http://purl.obolibrary.org/obo/GO_0050000 GO:0050001 biolink:MolecularActivity D-glutaminase activity Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate. MetaCyc:D-GLUTAMINASE-RXN|EC:3.5.1.35|RHEA:22840 go-plus.json D-glutamine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050001 GO:0050015 biolink:MolecularActivity kievitone hydratase activity Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone. RHEA:23604|KEGG_REACTION:R03622|EC:4.2.1.95|MetaCyc:KIEVITONE-HYDRATASE-RXN go-plus.json KHase activity|kievitone-hydrate hydro-lyase activity|kievitone-hydrate hydro-lyase (kievitone-forming) http://purl.obolibrary.org/obo/GO_0050015 GO:0050016 biolink:MolecularActivity kynurenine 7,8-hydroxylase activity Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor. EC:1.14.99.2|RHEA:11968|MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN go-plus.json kynurenic acid hydroxylase activity|kynurenic hydroxylase activity|kynurenate 7,8-hydroxylase activity|kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating) http://purl.obolibrary.org/obo/GO_0050016 GO:0050013 biolink:MolecularActivity 2-dehydropantoate aldolase activity Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde. EC:4.1.2.12|MetaCyc:KETOPANTOALDOLASE-RXN|RHEA:23276 go-plus.json 2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)|ketopantoaldolase activity|2-dehydropantoate formaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0050013 GO:0050014 biolink:MolecularActivity ketotetrose-phosphate aldolase activity Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate. RHEA:20932|KEGG_REACTION:R01014|MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN|EC:4.1.2.2 go-plus.json erythrulose-1-phosphate formaldehyde-lyase activity|erythrose-1-phosphate synthase activity|erythrulose-1-phosphate synthetase activity|phosphoketotetrose aldolase activity|erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming) http://purl.obolibrary.org/obo/GO_0050014 GO:0050019 biolink:MolecularActivity L-arabinitol 4-dehydrogenase activity Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH. MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN|KEGG_REACTION:R01903|EC:1.1.1.12|RHEA:16381 go-plus.json http://purl.obolibrary.org/obo/GO_0050019 GO:0050017 biolink:MolecularActivity L-3-cyanoalanine synthase activity Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine. MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN|EC:4.4.1.9|RHEA:17821 go-plus.json beta-cyanoalanine synthase activity|L-cysteine hydrogen-sulfide-lyase (adding HCN)|L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)|beta-cyano-L-alanine synthase activity|beta-cyanoalanine synthetase activity http://purl.obolibrary.org/obo/GO_0050017 GO:0050018 biolink:MolecularActivity L-amino-acid dehydrogenase activity Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH. RHEA:10396|EC:1.4.1.5|MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN go-plus.json L-amino-acid:NAD+ oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0050018 CL:0000798 biolink:Cell gamma-delta T cell A T cell that expresses a gamma-delta T cell receptor complex. go-plus.json gamma-delta T lymphocyte|gd T cell|gamma-delta T-cell|gamma-delta T-lymphocyte|gammadelta T cell http://purl.obolibrary.org/obo/CL_0000798 GO:0015609 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015609 CL:0000799 biolink:Cell immature gamma-delta T cell A gamma-delta T cell that has an immature phenotype. go-plus.json immature gamma-delta T-lymphocyte|immature gamma-delta T lymphocyte|immature gamma-delta T-cell http://purl.obolibrary.org/obo/CL_0000799 GO:0015605 biolink:MolecularActivity organophosphate ester transmembrane transporter activity Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0015605 GO:0015606 biolink:MolecularActivity spermidine transmembrane transporter activity Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0015606 GO:0015607 biolink:MolecularActivity ABC-type fatty-acyl-CoA transporter activity Catalysis of the reaction ATP + H(2)O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it. RHEA:15181|EC:7.6.2.4 go-plus.json ABC-type fatty-acyl-CoA transporter|fatty-acyl-CoA-transporting ATPase|ATPase-coupled fatty-acyl-CoA transmembrane transporter activity|fatty acyl CoA transporter activity|fatty-acyl-CoA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015607 GO:0015608 biolink:MolecularActivity carbohydrate-importing ABC transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in). TC:3.A.1.1.1 go-plus.json sugar transporter|carbohydrate-importing ATPase activity|carbohydrate uptake transporter activity http://purl.obolibrary.org/obo/GO_0015608 GO:0015601 biolink:MolecularActivity obsolete cystine/diaminopimelate porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). go-plus.json cystine/diaminopimelate porter activity http://purl.obolibrary.org/obo/GO_0015601 CL:0000790 biolink:Cell immature alpha-beta T cell An alpha-beta T cell that has an immature phenotype and has not completed T cell selection. go-plus.json immature alpha-beta T-cell|immature alpha-beta T-lymphocyte|immature alpha-beta T lymphocyte http://purl.obolibrary.org/obo/CL_0000790 CL:0000791 biolink:Cell mature alpha-beta T cell A alpha-beta T cell that has a mature phenotype. go-plus.json mature alpha-beta T lymphocyte|mature alpha-beta T-cell|mature alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/CL_0000791 GO:0015602 biolink:MolecularActivity obsolete leucine/isoleucine/valine porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in). go-plus.json leucine/isoleucine/valine porter activity http://purl.obolibrary.org/obo/GO_0015602 CL:0000792 biolink:Cell CD4-positive, CD25-positive, alpha-beta regulatory T cell A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. go-plus.json Treg|suppressor T-lymphocyte|CD4-positive, CD25-positive, alpha-beta regulatory T-cell|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte|suppressor T cell|suppressor T lymphocyte|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte|suppressor T-cell http://purl.obolibrary.org/obo/CL_0000792 GO:0015603 biolink:MolecularActivity iron chelate transmembrane transporter activity Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions. go-plus.json http://purl.obolibrary.org/obo/GO_0015603 GO:0015604 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015604 CL:0000793 biolink:Cell CD4-positive, alpha-beta intraepithelial T cell A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract. go-plus.json CD4-positive, alpha-beta intraepithelial T lymphocyte|IEL|CD4-positive, alpha-beta intraepithelial T-cell|intraepithelial lymphocyte|CD4-positive, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/CL_0000793 CHEBI:27150 biolink:ChemicalSubstance trisaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_27150 CHEBI:76195 biolink:ChemicalSubstance sapienoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76195 chebi_ph7_3 CL:0000794 biolink:Cell CD8-positive, alpha-beta cytotoxic T cell A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. go-plus.json killer T lymphocyte|CD8-positive, alpha-beta cytotoxic T-cell|CD8-positive, alpha-beta cytotoxic T-lymphocyte|cytotoxic T-cell|cytotoxic T-lymphocyte|killer T-cell|CD8-positive, alpha-beta cytotoxic T lymphocyte|killer T-lymphocyte|cytotoxic T cell|cytotoxic T lymphocyte|killer T cell http://purl.obolibrary.org/obo/CL_0000794 CL:0000795 biolink:Cell CD8-positive, alpha-beta regulatory T cell A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. go-plus.json suppressor T-cell|CD8+ T(reg)|suppressor T-lymphocyte|CD8-positive, alpha-beta regulatory T lymphocyte|CD8-positive Treg|CD8+ Treg|suppressor T cell|CD8+ regulatory T cell|suppressor T lymphocyte|CD8-positive, alpha-beta regulatory T-cell|CD8-positive, alpha-beta regulatory T-lymphocyte|CD8-positive, alpha-beta Treg|CD8-positive T(reg) http://purl.obolibrary.org/obo/CL_0000795 CL:0000796 biolink:Cell CD8-alpha-beta-positive, alpha-beta intraepithelial T cell A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. go-plus.json CD8-positive, alpha-beta intraepithelial T lymphocyte|IEL|CD8-positive, alpha-beta intraepithelial T-cell|CD8-positive, alpha-beta intraepithelial T-lymphocyte|intraepithelial lymphocyte http://purl.obolibrary.org/obo/CL_0000796 GO:0015600 biolink:MolecularActivity obsolete glutamate/aspartate porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). go-plus.json glutamate/aspartate porter activity http://purl.obolibrary.org/obo/GO_0015600 CHEBI:76194 biolink:ChemicalSubstance palmitoyl bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76194 chebi_ph7_3 CL:0000797 biolink:Cell alpha-beta intraepithelial T cell A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. go-plus.json alpha-beta intraepithelial T lymphocyte|IEL|alpha-beta intraepithelial T-cell|alpha-beta intraepithelial T-lymphocyte|intraepithelial lymphocyte http://purl.obolibrary.org/obo/CL_0000797 CHEBI:76197 biolink:ChemicalSubstance sapienate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76197 chebi_ph7_3 GO:0050011 biolink:MolecularActivity itaconyl-CoA hydratase activity Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O. EC:4.2.1.56|RHEA:13785|MetaCyc:ITACONYL-COA-HYDRATASE-RXN go-plus.json citramalyl-CoA hydro-lyase activity|citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)|itaconyl coenzyme A hydratase activity http://purl.obolibrary.org/obo/GO_0050011 GO:0050012 biolink:MolecularActivity juglone 3-hydroxylase activity Catalysis of the reaction: 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H+. KEGG_REACTION:R04327|EC:1.17.3.4|RHEA:18745|MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN go-plus.json naphthoquinone hydroxylase activity|juglone 3-monooxygenase activity|juglone hydroxylase activity|5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating) http://purl.obolibrary.org/obo/GO_0050012 GO:0050010 biolink:MolecularActivity isovitexin beta-glucosyltransferase activity Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP. RHEA:19529|KEGG_REACTION:R03686|EC:2.4.1.106|MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN go-plus.json UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity|isovitexin b-glucosyltransferase activity|UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050010 GO:1990354 biolink:CellularComponent activated SUMO-E1 ligase complex A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins. go-plus.json SUMO-SAE1/2 complex http://purl.obolibrary.org/obo/GO_1990354 GO:1990355 biolink:BiologicalProcess L-methionine salvage from methionine sulphoxide The generation of L-methionine from methionine sulphoxide. go-plus.json methionine salvage from methionine sulphoxide http://purl.obolibrary.org/obo/GO_1990355 GO:1990356 biolink:CellularComponent sumoylated E2 ligase complex A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase. go-plus.json http://purl.obolibrary.org/obo/GO_1990356 GO:1990357 biolink:CellularComponent terminal web An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990357 GO:1990350 biolink:CellularComponent glucose transporter complex A protein complex facilitating glucose transport into, out of or within a cell, or between cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990350 GO:0001099 biolink:MolecularActivity basal RNA polymerase II transcription machinery binding Binding to a component of the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase. go-plus.json basal RNAP II transcription machinery binding http://purl.obolibrary.org/obo/GO_0001099 GO:1990351 biolink:CellularComponent transporter complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990351 GO:1990352 biolink:CellularComponent BRE1 E3 ubiquitin ligase complex A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes. go-plus.json BRE1 E3 ubiquitin-protein ligase complex|BRE1 oligomer http://purl.obolibrary.org/obo/GO_1990352 GO:1990353 biolink:CellularComponent Fused-Smurf ubiquitin ligase complex A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation. go-plus.json http://purl.obolibrary.org/obo/GO_1990353 GO:0001095 biolink:MolecularActivity TFIIE-class transcription factor complex binding Binding to a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. go-plus.json TFIIE-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001095 GO:0001096 biolink:MolecularActivity TFIIF-class transcription factor complex binding Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. go-plus.json TFIIF-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001096 NCBITaxon:119089 biolink:OrganismalEntity Chromadorea go-plus.json Adenophorea http://purl.obolibrary.org/obo/NCBITaxon_119089 GO:0001097 biolink:MolecularActivity TFIIH-class transcription factor complex binding Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. go-plus.json TFIIH-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001097 GO:0001098 biolink:MolecularActivity basal transcription machinery binding Binding to a component of the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase. go-plus.json http://purl.obolibrary.org/obo/GO_0001098 GO:0001091 biolink:MolecularActivity RNA polymerase II general transcription initiation factor binding Binding to a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor. go-plus.json RNA polymerase II basal transcription factor binding http://purl.obolibrary.org/obo/GO_0001091 GO:0001092 biolink:MolecularActivity TFIIA-class transcription factor complex binding Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor. go-plus.json TFIIA-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001092 GO:0001093 biolink:MolecularActivity TFIIB-class transcription factor binding Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. go-plus.json http://purl.obolibrary.org/obo/GO_0001093 GO:0001094 biolink:MolecularActivity TFIID-class transcription factor complex binding Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. go-plus.json TFIID-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001094 CHEBI:134389 biolink:ChemicalSubstance beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_134389 chebi_ph7_3 GO:1990358 biolink:CellularComponent xylanosome A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose. go-plus.json xylanolytic complex http://purl.obolibrary.org/obo/GO_1990358 GO:1990359 biolink:BiologicalProcess stress response to zinc ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus. go-plus.json stress response to zinc|response to zinc toxicity|response to zinc ion stress http://purl.obolibrary.org/obo/GO_1990359 CHEBI:134386 biolink:ChemicalSubstance 2-acylphloroglucinol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134386 chebi_ph7_3 GO:1990365 biolink:BiologicalProcess obsolete response to phenol OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phenols. go-plus.json response to phenol http://purl.obolibrary.org/obo/GO_1990365 GO:1990366 biolink:BiologicalProcess obsolete response to organic acid OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic acid. go-plus.json response to organic acid http://purl.obolibrary.org/obo/GO_1990366 GO:1990367 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990367 GO:1990368 biolink:BiologicalProcess obsolete process resulting in tolerance to hydrolysate OBSOLETE. A response that results in a state of tolerance to hydrolysate (product of hydrolysis). go-plus.json process resulting in tolerance to hydrolysate http://purl.obolibrary.org/obo/GO_1990368 GO:1990361 biolink:CellularComponent PKM2 pyruvate kinase complex A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013). go-plus.json PKM2 homotetramer http://purl.obolibrary.org/obo/GO_1990361 GO:1990362 biolink:MolecularActivity butanol dehydrogenase activity Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+. RHEA:33199 go-plus.json http://purl.obolibrary.org/obo/GO_1990362 GO:1990363 biolink:BiologicalProcess obsolete response to hydrolysate OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of hydrolysate (any product of hydrolysis). go-plus.json response to hydrolysate http://purl.obolibrary.org/obo/GO_1990363 GO:1990364 biolink:BiologicalProcess obsolete response to aldehyde OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde. go-plus.json response to aldehyde http://purl.obolibrary.org/obo/GO_1990364 GO:1990360 biolink:CellularComponent PKM2 protein kinase complex A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer. go-plus.json PKM2-SAICAR complex|PKM2-SAICAR protein kinase complex http://purl.obolibrary.org/obo/GO_1990360 CHEBI:134398 biolink:ChemicalSubstance D-proline betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134398 chebi_ph7_3 GO:0039698 biolink:BiologicalProcess polyadenylation of viral mRNA by polymerase stuttering Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail. VZ:1916 go-plus.json polyA stuttering http://purl.obolibrary.org/obo/GO_0039698 CHEBI:134399 biolink:ChemicalSubstance ADP-5-ethyl-4-methylthiazole-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134399 GO:0039699 biolink:BiologicalProcess viral mRNA cap methylation Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs. go-plus.json IFIT mRNA restriction evasion by virus http://purl.obolibrary.org/obo/GO_0039699 GO:0039692 biolink:BiologicalProcess single stranded viral RNA replication via double stranded DNA intermediate A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II. VZ:1937 go-plus.json retroviral genome replication|viral ssRNA replication via dsDNA intermediate http://purl.obolibrary.org/obo/GO_0039692 GO:0039693 biolink:BiologicalProcess viral DNA genome replication The replication of a viral DNA genome. go-plus.json viral DNA-dependent DNA replication|DNA-dependent viral DNA replication|viral DNA replication http://purl.obolibrary.org/obo/GO_0039693 GO:0039690 biolink:BiologicalProcess positive stranded viral RNA replication A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA. VZ:1116 go-plus.json ss(+) viral RNA replication http://purl.obolibrary.org/obo/GO_0039690 CHEBI:134390 biolink:ChemicalSubstance beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134390 chebi_ph7_3 GO:0039691 biolink:BiologicalProcess double stranded viral RNA replication A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA. VZ:1936 go-plus.json http://purl.obolibrary.org/obo/GO_0039691 CHEBI:134391 biolink:ChemicalSubstance 3,4,6-trichlorocatechol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134391 chebi_ph7_3 GO:0039696 biolink:BiologicalProcess RNA-templated viral transcription A transcription process that uses viral RNA as a template. go-plus.json http://purl.obolibrary.org/obo/GO_0039696 CHEBI:134396 biolink:ChemicalSubstance secondary allylic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134396 chebi_ph7_3 GO:1990369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990369 CHEBI:134397 biolink:ChemicalSubstance tertiary allylic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134397 chebi_ph7_3 GO:0039697 biolink:BiologicalProcess negative stranded viral RNA transcription A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template. VZ:1096 go-plus.json http://purl.obolibrary.org/obo/GO_0039697 CHEBI:134394 biolink:ChemicalSubstance primary allylic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134394 chebi_ph7_3 GO:0039694 biolink:BiologicalProcess viral RNA genome replication The replication of a viral RNA genome. go-plus.json http://purl.obolibrary.org/obo/GO_0039694 GO:0039695 biolink:BiologicalProcess DNA-templated viral transcription A transcription process that uses a viral DNA as a template. VZ:1942 go-plus.json http://purl.obolibrary.org/obo/GO_0039695 GO:1990376 biolink:BiologicalProcess obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition. go-plus.json http://purl.obolibrary.org/obo/GO_1990376 GO:1990377 biolink:CellularComponent organomineral extracellular matrix An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight. go-plus.json http://purl.obolibrary.org/obo/GO_1990377 GO:1990378 biolink:CellularComponent upstream stimulatory factor complex A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters. go-plus.json USF1-USF2 heterodimer|USF2 homodimer|USF1 homodimer|USF complex http://purl.obolibrary.org/obo/GO_1990378 GO:1990379 biolink:BiologicalProcess lipid transport across blood-brain barrier The directed movement of lipid molecules passing through the blood-brain barrier. go-plus.json lipid transport across blood brain barrier http://purl.obolibrary.org/obo/GO_1990379 GO:1990372 biolink:BiologicalProcess obsolete process resulting in tolerance to organic acid OBSOLETE. A response that results in a state of tolerance to organic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1990372 GO:0001077 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001077 GO:0001078 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001078 GO:1990373 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990373 GO:1990374 biolink:CellularComponent Kir2 inward rectifier potassium channel complex A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells. go-plus.json Kir2.1 complex http://purl.obolibrary.org/obo/GO_1990374 GO:0001079 biolink:BiologicalProcess nitrogen catabolite regulation of transcription from RNA polymerase II promoter A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources. go-plus.json regulation of transcription from RNA polymerase II promoter by nitrogen catabolites http://purl.obolibrary.org/obo/GO_0001079 GO:1990375 biolink:BiologicalProcess baculum development The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure. go-plus.json os penis development|penis bone development|penile bone development http://purl.obolibrary.org/obo/GO_1990375 GO:0001073 biolink:MolecularActivity transcription antitermination factor activity, DNA binding Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein. go-plus.json DNA binding transcription antitermination factor activity http://purl.obolibrary.org/obo/GO_0001073 GO:0001074 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly OBSOLETE. Binding to a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter. go-plus.json transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly http://purl.obolibrary.org/obo/GO_0001074 GO:0001075 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001075 GO:1990370 biolink:BiologicalProcess obsolete process resulting in tolerance to aldehyde OBSOLETE. A response that results in a state of tolerance to aldehyde. go-plus.json http://purl.obolibrary.org/obo/GO_1990370 GO:0001076 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase II transcription factor binding OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json RNA polymerase II transcription factor binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001076 GO:1990371 biolink:BiologicalProcess obsolete process resulting in tolerance to phenol OBSOLETE. A response that results in a state of tolerance to phenol. go-plus.json http://purl.obolibrary.org/obo/GO_1990371 GO:0001070 biolink:MolecularActivity RNA-binding transcription regulator activity A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences. go-plus.json RNA binding transcription factor activity|RNA binding transcription regulator activity http://purl.obolibrary.org/obo/GO_0001070 GO:0001071 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001071 GO:0001072 biolink:MolecularActivity transcription antitermination factor activity, RNA binding Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein. go-plus.json RNA binding transcription antitermination factor activity http://purl.obolibrary.org/obo/GO_0001072 CHEBI:134367 biolink:ChemicalSubstance 2-bromocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134367 GO:0039689 biolink:BiologicalProcess negative stranded viral RNA replication A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA). VZ:1096 go-plus.json (-)ss viral RNA replication http://purl.obolibrary.org/obo/GO_0039689 CHEBI:134368 biolink:ChemicalSubstance 5a,11a-dehydrooxytetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_134368 GO:0039687 biolink:BiologicalProcess viral DNA strand displacement replication A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA). VZ:1940 go-plus.json http://purl.obolibrary.org/obo/GO_0039687 GO:0039688 biolink:BiologicalProcess viral double stranded DNA replication via reverse transcription A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands. VZ:1938 go-plus.json dsDNA replication via RNA intermediate|viral RNA-dependent DNA replication|RNA-dependent viral DNA replication http://purl.obolibrary.org/obo/GO_0039688 CHEBI:134366 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_134366 GO:0039681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0039681 GO:0039682 biolink:BiologicalProcess rolling circle viral DNA replication A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0039682 GO:0039680 biolink:BiologicalProcess actin-dependent intracellular transport of virus towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments. VZ:991 go-plus.json actin-dependent intracellular transport of viral material towards nucleus|actin-dependent inwards viral transport http://purl.obolibrary.org/obo/GO_0039680 GO:0039685 biolink:BiologicalProcess rolling hairpin viral DNA replication A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA. VZ:2656 go-plus.json ssDNA rolling hairpin viral DNA replication http://purl.obolibrary.org/obo/GO_0039685 CHEBI:134363 biolink:ChemicalSubstance tertiary amine oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_134363 GO:0039686 biolink:BiologicalProcess bidirectional double-stranded viral DNA replication A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions. VZ:1939 go-plus.json viral bidirectional dsDNA replication http://purl.obolibrary.org/obo/GO_0039686 CHEBI:134364 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_134364 GO:0039683 biolink:BiologicalProcess rolling circle double-stranded viral DNA replication A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome. VZ:2676 go-plus.json dsDNA rolling circle replication http://purl.obolibrary.org/obo/GO_0039683 CHEBI:134361 biolink:ChemicalSubstance allylic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134361 chebi_ph7_3 CHEBI:134362 biolink:ChemicalSubstance homoallylic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134362 chebi_ph7_3 GO:0039684 biolink:BiologicalProcess rolling circle single-stranded viral DNA replication A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome. VZ:1941 go-plus.json ssDNA rolling circle replication http://purl.obolibrary.org/obo/GO_0039684 GO:1990387 biolink:BiologicalProcess isogloboside biosynthetic process The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides). go-plus.json http://purl.obolibrary.org/obo/GO_1990387 GO:1990388 biolink:BiologicalProcess xylem-to-phloem iron transport The directed movement of iron ions into the phloem from the xylem. go-plus.json http://purl.obolibrary.org/obo/GO_1990388 GO:1990389 biolink:CellularComponent CUE1-UBC7 ubiquitin-conjugating enzyme complex A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1. go-plus.json CUE1-UBC7 ubiquitin-conjugating enzyme (E2) http://purl.obolibrary.org/obo/GO_1990389 GO:1990383 biolink:BiologicalProcess cellular response to biotin starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin. go-plus.json http://purl.obolibrary.org/obo/GO_1990383 GO:0001088 biolink:MolecularActivity obsolete transcription factor activity, TFIIE-class binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TFIIE-class binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001088 GO:1990384 biolink:BiologicalProcess hyaloid vascular plexus regression The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression. go-plus.json http://purl.obolibrary.org/obo/GO_1990384 GO:0001089 biolink:MolecularActivity obsolete transcription factor activity, TFIIF-class transcription factor binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TFIIF-class binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001089 GO:1990385 biolink:CellularComponent meiotic spindle midzone The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap. go-plus.json http://purl.obolibrary.org/obo/GO_1990385 GO:1990386 biolink:BiologicalProcess mitotic cleavage furrow ingression Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed. go-plus.json http://purl.obolibrary.org/obo/GO_1990386 GO:0001084 biolink:MolecularActivity obsolete transcription factor activity, TFIID-class binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TFIID-class binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001084 GO:1990380 biolink:MolecularActivity Lys48-specific deubiquitinase activity Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein. Reactome:R-HSA-5690870 go-plus.json K48-specific deubiquitinating activity|K48-specific deubiquitinase activity http://purl.obolibrary.org/obo/GO_1990380 GO:0001085 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001085 GO:0001086 biolink:MolecularActivity obsolete transcription factor activity, TFIIA-class binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TFIIA-class binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001086 GO:1990381 biolink:MolecularActivity ubiquitin-specific protease binding Binding to a ubiquitin-specific protease. go-plus.json deubiquitinating enzyme binding|deubiquitinase binding http://purl.obolibrary.org/obo/GO_1990381 GO:0001087 biolink:MolecularActivity obsolete transcription factor activity, TFIIB-class binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TFIIB-class binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001087 GO:1990382 biolink:BiologicalProcess obsolete melanosome assembly OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. go-plus.json melanosome biogenesis http://purl.obolibrary.org/obo/GO_1990382 GO:0001080 biolink:BiologicalProcess nitrogen catabolite activation of transcription from RNA polymerase II promoter A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources. go-plus.json positive regulation of transcription from RNA polymerase II promoter by nitrogen catabolites http://purl.obolibrary.org/obo/GO_0001080 GO:0001081 biolink:BiologicalProcess nitrogen catabolite repression of transcription from RNA polymerase II promoter A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources. go-plus.json negative regulation of transcription from RNA polymerase II promoter by nitrogen catabolites http://purl.obolibrary.org/obo/GO_0001081 GO:0001082 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase I transcription factor binding OBSOLETE. Binding to an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json RNA polymerase I transcription factor binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001082 GO:0001083 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase II basal transcription factor binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json RNA polymerase II basal transcription factor binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001083 GO:0039678 biolink:BiologicalProcess viral genome ejection through host cell envelope Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm. go-plus.json phage genome ejection|viral genome injection through bacterial membranes http://purl.obolibrary.org/obo/GO_0039678 GO:0039679 biolink:CellularComponent viral occlusion body A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host. VZ:1949 go-plus.json http://purl.obolibrary.org/obo/GO_0039679 GO:0039676 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0039676 GO:0001090 biolink:MolecularActivity obsolete transcription factor activity, TFIIH-class binding OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TFIIH-class binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001090 GO:0039677 biolink:BiologicalProcess exit of virus from host cell nucleus via nuclear envelope disassembly The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus. VZ:2176 go-plus.json exit of virus from host cell nucleus via nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_0039677 GO:0039670 biolink:CellularComponent viral capsid, turret A turret-like appendage formed at the vertices of an icosahedral capsid. go-plus.json http://purl.obolibrary.org/obo/GO_0039670 GO:0039671 biolink:BiologicalProcess evasion by virus of host natural killer cell activity Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells. go-plus.json protection by virus against host NK cell cytotoxicity|modulation of host NK-cell activity by virus|evasion by virus of host natural killer cell response|evasion by virus of host NK cell killing|suppression by virus of host natural killer cell function|viral immunoevasion of host NK cell http://purl.obolibrary.org/obo/GO_0039671 CHEBI:134371 biolink:ChemicalSubstance 2-acyl-4-prenylphloroglucinol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134371 chebi_ph7_3 GO:0039674 biolink:BiologicalProcess exit of virus from host cell nucleus The directed movement of the viral genome or a viral particle out of the host cell nucleus. VZ:2177 go-plus.json http://purl.obolibrary.org/obo/GO_0039674 GO:0039675 biolink:BiologicalProcess exit of virus from host cell nucleus through nuclear pore The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore. VZ:1953 go-plus.json nuclear pore exit of virus|exit of virus from host cell nucleus through nuclear pore complex|viral enome export through nuclear pore http://purl.obolibrary.org/obo/GO_0039675 GO:0039672 biolink:BiologicalProcess suppression by virus of host natural killer cell activation Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host. go-plus.json suppression by virus of host NK-cell activation http://purl.obolibrary.org/obo/GO_0039672 GO:0039673 biolink:BiologicalProcess evasion by virus of host dendritic cell activity Any process by which a virus avoids the effects mediated by the host organism's dendritic cells. go-plus.json evasion by virus of host dendritic cell response|impairing dendritic cell function by virus|modulation of host dendritic cell activity by virus http://purl.obolibrary.org/obo/GO_0039673 GO:0001059 biolink:BiologicalProcess transcription by RNA polymerase IV The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter. go-plus.json transcription from RNA pol IV promoter|transcription from RNA polymerase IV promoter http://purl.obolibrary.org/obo/GO_0001059 GO:1990310 biolink:MolecularActivity type-III dockerin domain binding Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain. go-plus.json http://purl.obolibrary.org/obo/GO_1990310 CHEBI:506227 biolink:ChemicalSubstance N-acetyl-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_506227 chebi_ph7_3 GO:1990311 biolink:MolecularActivity type-I cohesin domain binding Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain. go-plus.json http://purl.obolibrary.org/obo/GO_1990311 GO:1990312 biolink:MolecularActivity type-II cohesin domain binding Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain. go-plus.json http://purl.obolibrary.org/obo/GO_1990312 GO:1990313 biolink:MolecularActivity type-III cohesin domain binding Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain. go-plus.json http://purl.obolibrary.org/obo/GO_1990313 GO:0001055 biolink:MolecularActivity RNA polymerase II activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. Reactome:R-HSA-6814559|Reactome:R-HSA-6814549 go-plus.json DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0001055 GO:0001056 biolink:MolecularActivity RNA polymerase III activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. Reactome:R-HSA-1964482 go-plus.json DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_0001056 GO:0001057 biolink:MolecularActivity RNA polymerase IV activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter http://purl.obolibrary.org/obo/GO_0001057 GO:0001058 biolink:MolecularActivity RNA polymerase V activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter http://purl.obolibrary.org/obo/GO_0001058 GO:0001051 biolink:MolecularActivity plastid single-subunit type RNA polymerase binding Binding to a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6. go-plus.json http://purl.obolibrary.org/obo/GO_0001051 GO:0001052 biolink:MolecularActivity plastid PEP RNA polymerase core enzyme binding Binding to a bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0001052 GO:0001053 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001053 GO:0001054 biolink:MolecularActivity RNA polymerase I activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0001054 GO:0001050 biolink:MolecularActivity single-subunit type RNA polymerase binding Binding to a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6. go-plus.json T7-type RNA polymerase binding|T3/T7 type RNA polymerase binding|T3-type RNA polymerase binding|SP6-type RNA polymerase binding http://purl.obolibrary.org/obo/GO_0001050 GO:0039667 biolink:BiologicalProcess viral entry into host cell via pilus retraction The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus. go-plus.json http://purl.obolibrary.org/obo/GO_0039667 CHEBI:134345 biolink:ChemicalSubstance deoxyhumulone go-plus.json http://purl.obolibrary.org/obo/CHEBI_134345 chebi_ph7_3 GO:0039668 biolink:BiologicalProcess viral entry into host cell via pilus basal pore The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way. go-plus.json filamentous viral entry into host cell via pilus retraction http://purl.obolibrary.org/obo/GO_0039668 PR:000004972 biolink:Protein calcitonin receptor A calcitonin receptor protein that is a translation product of the human CALCR gene or a 1:1 ortholog thereof. go-plus.json CALCR|CT-R http://purl.obolibrary.org/obo/PR_000004972 CHEBI:134346 biolink:ChemicalSubstance 2-acyl-4,6-diprenylphloroglucinol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134346 chebi_ph7_3 GO:0039665 biolink:BiologicalProcess permeabilization of host organelle membrane involved in viral entry into host cell Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm. VZ:985 go-plus.json viral penetration via permeabilization of host organellar membrane|viral penetration via perforation of host organellar membrane by virus|viral penetration via host endosomal membrane disruption by virus|viral entry into host cell via permeabilization of host organelle membrane|viral membrane-penetration protein http://purl.obolibrary.org/obo/GO_0039665 CHEBI:134343 biolink:ChemicalSubstance lupulone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134343 chebi_ph7_3 GO:0039666 biolink:BiologicalProcess virion attachment to host cell pilus The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side. VZ:981 go-plus.json pilus-adsorption protein|viral attachment to host cell pilus|pilus-mediated viral adsorption onto host cell|pilus-mediated viral attachment to host cell http://purl.obolibrary.org/obo/GO_0039666 CHEBI:134344 biolink:ChemicalSubstance ergothioneine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134344 chebi_ph7_3 CHEBI:134349 biolink:ChemicalSubstance colupulone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134349 chebi_ph7_3 GO:0015696 biolink:BiologicalProcess ammonium transport The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals. go-plus.json ammonia transport http://purl.obolibrary.org/obo/GO_0015696 GO:0015697 biolink:BiologicalProcess quaternary ammonium group transport The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. go-plus.json quaternary amine transport|quaternary ammonium compound transport http://purl.obolibrary.org/obo/GO_0015697 CHEBI:134347 biolink:ChemicalSubstance glandicoline B go-plus.json http://purl.obolibrary.org/obo/CHEBI_134347 chebi_ph7_3 GO:0039669 biolink:BiologicalProcess viral entry into host cell via pilus retraction and membrane fusion The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0039669 GO:0015698 biolink:BiologicalProcess inorganic anion transport The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0015698 CHEBI:134348 biolink:ChemicalSubstance beta-bitter acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134348 chebi_ph7_3 GO:0015699 biolink:BiologicalProcess antimonite transport The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015699 GO:1990318 biolink:CellularComponent collagen type XIX trimer A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990318 GO:0015692 biolink:BiologicalProcess lead ion transport The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015692 GO:0039660 biolink:MolecularActivity structural constituent of virion The action of a molecule that contributes to the structural integrity of a virion. go-plus.json viral matrix protein http://purl.obolibrary.org/obo/GO_0039660 GO:0015693 biolink:BiologicalProcess magnesium ion transport The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json magnesium transport http://purl.obolibrary.org/obo/GO_0015693 GO:1990319 biolink:CellularComponent collagen type XX trimer A collagen homotrimer of alpha1(XX) chains. go-plus.json http://purl.obolibrary.org/obo/GO_1990319 GO:0015694 biolink:BiologicalProcess mercury ion transport The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json mercury transport|mercuric ion transport http://purl.obolibrary.org/obo/GO_0015694 PR:000004978 biolink:Protein calmodulin A protein that is a translation product of the human CALM1, CALM2, or CALM3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json CALML2|CALM|CAMIII|CAMC|CaM|CAM3 http://purl.obolibrary.org/obo/PR_000004978 GO:0015695 biolink:BiologicalProcess organic cation transport The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0015695 GO:1990314 biolink:BiologicalProcess cellular response to insulin-like growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus. go-plus.json cellular response to insulin-like growth factor http://purl.obolibrary.org/obo/GO_1990314 GO:0039663 biolink:BiologicalProcess membrane fusion involved in viral entry into host cell Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell. go-plus.json fusion of virus membrane with host membrane during viral entry|fusion of virus membrane with host membrane|viral entry into host cell via membrane fusion http://purl.obolibrary.org/obo/GO_0039663 CHEBI:134341 biolink:ChemicalSubstance 2-(3-methylbutanoyl)-4-prenylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134341 chebi_ph7_3 GO:0039664 biolink:BiologicalProcess lysis of host organelle involved in viral entry into host cell The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm. VZ:984 go-plus.json viral entry into host cell via lysis of host organelle membrane|viral penetration via lysis of host organellar membrane|viral entry into host cell via endosome membrane lysis|viral membrane-lytic protein http://purl.obolibrary.org/obo/GO_0039664 GO:1990315 biolink:CellularComponent Mcs4 RR-MAPKKK complex A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress. go-plus.json http://purl.obolibrary.org/obo/GO_1990315 CHEBI:134342 biolink:ChemicalSubstance 2-isobutyryl-4-prenylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134342 chebi_ph7_3 GO:0039661 biolink:CellularComponent host organelle outer membrane The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0039661 GO:0015690 biolink:BiologicalProcess aluminum cation transport The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json aluminium transport|aluminum ion transport|aluminium ion transport|aluminum transport http://purl.obolibrary.org/obo/GO_0015690 GO:1990316 biolink:CellularComponent Atg1/ULK1 kinase complex A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation. go-plus.json autophagy-initiation complex|ULK1-ATG13-RB1CC1 complex|ULK1 signaling complex|ULK1 complex|ULK1-ATG13-FIP200 complex|Atg1p signalling complex|ATG1/ULK1 signaling complex|ULK complex|ATG1-ATG13 complex|ATG1 kinase complex http://purl.obolibrary.org/obo/GO_1990316 GO:1990317 biolink:CellularComponent Gin4 complex A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved. go-plus.json Gin4-septin complex http://purl.obolibrary.org/obo/GO_1990317 GO:0039662 biolink:CellularComponent host cell outer membrane A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell. go-plus.json outer membrane of host cell|host cell envelope outer membrane http://purl.obolibrary.org/obo/GO_0039662 GO:0015691 biolink:BiologicalProcess cadmium ion transport The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json cadmium transport http://purl.obolibrary.org/obo/GO_0015691 CHEBI:134340 biolink:ChemicalSubstance 2-(2-methylbutanoyl)-4-prenylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134340 chebi_ph7_3 GO:1990321 biolink:CellularComponent collagen type XXII trimer A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts. go-plus.json http://purl.obolibrary.org/obo/GO_1990321 GO:1990322 biolink:CellularComponent collagen type XXIII trimer A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990322 GO:1990323 biolink:CellularComponent collagen type XXIV trimer A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development. go-plus.json http://purl.obolibrary.org/obo/GO_1990323 GO:1990324 biolink:CellularComponent collagen type XXVI trimer A collagen homotrimer of alpha1(XXVI) chains. go-plus.json http://purl.obolibrary.org/obo/GO_1990324 PO:0004511 biolink:OntologyClass seed trichome A trichome that develops from seed coat epidermis. go-plus.json pubescence (related)|seed hair (exact)|種子毛（毛茸、糸状体、毛状突起体） (Japanese, exact)|tricoma de la semilla (Spanish, exact) http://purl.obolibrary.org/obo/PO_0004511 GO:0001066 biolink:MolecularActivity plastid single subunit type RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json http://purl.obolibrary.org/obo/GO_0001066 NCBITaxon:39947 biolink:OrganismalEntity Oryza sativa Japonica Group go-plus.json Oryza sativa subsp. japonica|Japonica rice|Japanese rice|Oryza sativa (japonica cultivar-group) http://purl.obolibrary.org/obo/NCBITaxon_39947 GO:0001067 biolink:MolecularActivity transcription regulatory region nucleic acid binding Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair. go-plus.json regulatory region nucleic acid binding http://purl.obolibrary.org/obo/GO_0001067 GO:0001068 biolink:MolecularActivity transcription regulatory region RNA binding Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon. go-plus.json http://purl.obolibrary.org/obo/GO_0001068 GO:1990320 biolink:CellularComponent collagen type XXI trimer A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle. go-plus.json http://purl.obolibrary.org/obo/GO_1990320 GO:0001069 biolink:MolecularActivity regulatory region RNA binding Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0001069 GO:0001062 biolink:MolecularActivity obsolete plastid PEP-A RNA polymerase activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json http://purl.obolibrary.org/obo/GO_0001062 GO:0001063 biolink:MolecularActivity obsolete plastid PEP-B RNA polymerase activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json http://purl.obolibrary.org/obo/GO_0001063 GO:0001064 biolink:MolecularActivity single subunit type RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json T3/T7 type RNA polymerase activity http://purl.obolibrary.org/obo/GO_0001064 GO:0001065 biolink:MolecularActivity mitochondrial single subunit type RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json http://purl.obolibrary.org/obo/GO_0001065 GO:0001060 biolink:BiologicalProcess transcription by RNA polymerase V The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter. go-plus.json transcription from RNA polymerase V promoter|transcription from RNA pol V promoter http://purl.obolibrary.org/obo/GO_0001060 GO:0001061 biolink:MolecularActivity obsolete bacterial-type RNA polymerase activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. go-plus.json http://purl.obolibrary.org/obo/GO_0001061 CHEBI:134356 biolink:ChemicalSubstance 8-methylmenaquinone-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134356 chebi_ph7_3 GO:0039656 biolink:BiologicalProcess modulation by virus of host gene expression The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. go-plus.json regulation by virus of host gene expression http://purl.obolibrary.org/obo/GO_0039656 GO:0039657 biolink:BiologicalProcess suppression by virus of host gene expression Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. VZ:1582 go-plus.json host gene expression shutoff by virus http://purl.obolibrary.org/obo/GO_0039657 CHEBI:134357 biolink:ChemicalSubstance 8-methylmenaquinol-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134357 chebi_ph7_3 GO:0039654 biolink:BiologicalProcess fusion of virus membrane with host endosome membrane Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell. VZ:992 go-plus.json viral penetration via endocytosis followed by caveolae-mediated membrane fusion with the endosome membrane|viral penetration via endocytosis followed by clathrin-mediated membrane fusion with the endosome membrane|viral entry into host cell via endocytosis followed by membrane fusion with host endosome|viral entry into host cell via endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via caveolin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by membrane fusion with the endosome membrane|fusion of virus membrane with host endosomal membrane http://purl.obolibrary.org/obo/GO_0039654 CHEBI:134354 biolink:ChemicalSubstance deoxyadlupulone go-plus.json http://purl.obolibrary.org/obo/CHEBI_134354 chebi_ph7_3 GO:0039655 biolink:BiologicalProcess obsolete transport of virus in host, cell to cell via plasmodesmata OBSOLETE. The transport of a virus between adjacent cells in a multicellular organism using plasmodesmata. Plasmodesma is a fine cytoplasmic channel found in all higher plants, which connects the cytoplasm of one cell to that of an adjacent cell. VZ:1018 go-plus.json viral movement protein|spread of virus in host, cell to cell via plasmodesmata http://purl.obolibrary.org/obo/GO_0039655 GO:0039658 biolink:CellularComponent TBK1-IKKE-DDX3 complex A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3. go-plus.json TBK1-IKBKE-DDX3 complex http://purl.obolibrary.org/obo/GO_0039658 CHEBI:134358 biolink:ChemicalSubstance 8-geranylumbelliferone go-plus.json http://purl.obolibrary.org/obo/CHEBI_134358 chebi_ph7_3 CHEBI:134359 biolink:ChemicalSubstance 8-geranylesculetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_134359 chebi_ph7_3 GO:0039659 biolink:BiologicalProcess obsolete suppression by virus of host TBK1-IKBKE-DDX3 complex activity OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TBK1-IKBKE-DDX3 complex. VZ:719 go-plus.json suppression by virus of host TBK1-IKKE-DDX3 complex activity|inhibition of host TBK1-IKBKE-DDX3 complex by virus http://purl.obolibrary.org/obo/GO_0039659 GO:1990329 biolink:CellularComponent IscS-TusA complex A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups. go-plus.json http://purl.obolibrary.org/obo/GO_1990329 GO:1990325 biolink:CellularComponent collagen type XXVII trimer A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone. go-plus.json http://purl.obolibrary.org/obo/GO_1990325 GO:0039652 biolink:BiologicalProcess activation by virus of host NF-kappaB transcription factor activity Any process in which a virus starts, promotes, or enhances the activity of the host transcription factor NF-kappaB. VZ:841 go-plus.json activation of host NF-kappa-B by virus http://purl.obolibrary.org/obo/GO_0039652 CHEBI:134352 biolink:ChemicalSubstance adlupulone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134352 chebi_ph7_3 GO:0039653 biolink:BiologicalProcess suppression by virus of host transcription Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors. VZ:1577 go-plus.json suppression by virus of host DNA-dependent transcription|host transcription shutoff by virus http://purl.obolibrary.org/obo/GO_0039653 GO:1990326 biolink:CellularComponent collagen type XXVIII trimer A collagen homotrimer of alpha1(XXVIII) chains. go-plus.json http://purl.obolibrary.org/obo/GO_1990326 CHEBI:134353 biolink:ChemicalSubstance deoxycohumulone go-plus.json http://purl.obolibrary.org/obo/CHEBI_134353 chebi_ph7_3 GO:0039650 biolink:BiologicalProcess suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process. go-plus.json inhibition of host caspases by virus http://purl.obolibrary.org/obo/GO_0039650 GO:1990327 biolink:CellularComponent collagen type XXV trimer A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990327 CHEBI:134350 biolink:ChemicalSubstance lipid A 4'-(2-aminoethyl diphosphate) oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134350 chebi_ph7_3 GO:0039651 biolink:BiologicalProcess induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process Any process in which a virus increases the frequency, rate or extent of host cysteine-type endopeptidase activity (also called caspase activity) which contributes to the apoptotic process. go-plus.json induction by virus of host caspase activity|activation of host caspases by virus http://purl.obolibrary.org/obo/GO_0039651 GO:1990328 biolink:CellularComponent RPB4-RPB7 complex A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways. go-plus.json RNA polymerase II, RPB4-RPB7 subcomplex http://purl.obolibrary.org/obo/GO_1990328 CHEBI:134351 biolink:ChemicalSubstance lipid A 1-(2-aminoethyl diphosphate) oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134351 chebi_ph7_3 GO:1990332 biolink:CellularComponent Ire1 complex A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript. go-plus.json ERN1 complex|IRE1 dimer http://purl.obolibrary.org/obo/GO_1990332 GO:0001037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001037 GO:1990333 biolink:CellularComponent mitotic checkpoint complex, CDC20-MAD2 subcomplex A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20. go-plus.json CDC20-MAD2 complex http://purl.obolibrary.org/obo/GO_1990333 GO:0001038 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001038 GO:1990334 biolink:CellularComponent Bfa1-Bub2 complex A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation. go-plus.json http://purl.obolibrary.org/obo/GO_1990334 GO:0001039 biolink:MolecularActivity RNA polymerase III hybrid type promoter sequence-specific DNA binding Binding to a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene. go-plus.json RNA polymerase III hybrid type promoter DNA binding http://purl.obolibrary.org/obo/GO_0001039 CHEBI:76106 biolink:ChemicalSubstance rac-laudanosoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_76106 GO:1990335 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990335 GO:0001033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001033 GO:0001034 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001034 GO:0001035 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001035 GO:1990330 biolink:CellularComponent IscS-IscU complex A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group. go-plus.json http://purl.obolibrary.org/obo/GO_1990330 GO:1990331 biolink:CellularComponent Hpa2 acetyltransferase complex A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_1990331 GO:0001036 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001036 GO:0001030 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001030 GO:0001031 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001031 GO:0001032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001032 GO:0039645 biolink:BiologicalProcess modulation by virus of host G1/S transition checkpoint Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint. VZ:880 go-plus.json G1/S host cell cycle checkpoint dysregulation by virus http://purl.obolibrary.org/obo/GO_0039645 GO:0015678 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015678 GO:0039646 biolink:BiologicalProcess modulation by virus of host G0/G1 transition checkpoint Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint. VZ:881 go-plus.json G0/G1 host cell cycle checkpoint dysregulation by virus http://purl.obolibrary.org/obo/GO_0039646 GO:0015679 biolink:BiologicalProcess plasma membrane copper ion transport The directed movement of copper ions across the plasma membrane. go-plus.json plasma membrane copper transport http://purl.obolibrary.org/obo/GO_0015679 GO:0039643 biolink:CellularComponent host cell viral nucleoid The region of a host cell that contains the viral genome. go-plus.json http://purl.obolibrary.org/obo/GO_0039643 GO:0039644 biolink:BiologicalProcess suppression by virus of host NF-kappaB transcription factor activity Any process in which a virus stops, prevents, or reduces the activity of host NF-kappaB activity. VZ:695 go-plus.json inhibition of host NF-kappa-B by virus http://purl.obolibrary.org/obo/GO_0039644 GO:0015674 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015674 GO:0039649 biolink:BiologicalProcess modulation by virus of host ubiquitin-protein ligase activity The process in which a virus effects a change in host ubiquitin-protein ligase activity. Ubiquitin-protein ligase activity catalyzes the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. go-plus.json modulation of host E3 ubiquitin ligases by virus http://purl.obolibrary.org/obo/GO_0039649 GO:0015675 biolink:BiologicalProcess nickel cation transport The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015675 GO:0039647 biolink:BiologicalProcess suppression by virus of host poly(A)-binding protein activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation. go-plus.json suppression by virus of host PABP activity|inhibition of host poly(A)-binding protein by virus http://purl.obolibrary.org/obo/GO_0039647 GO:0015676 biolink:BiologicalProcess vanadium ion transport The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015676 CHEBI:134326 biolink:ChemicalSubstance 2-(2-methylbutanoyl)phloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134326 chebi_ph7_3 GO:0039648 biolink:BiologicalProcess modulation by virus of host protein ubiquitination Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein. go-plus.json modulation of host ubiquitin pathway by virus http://purl.obolibrary.org/obo/GO_0039648 GO:0015677 biolink:BiologicalProcess copper ion import The directed movement of copper ions into a cell or organelle. go-plus.json copper ion uptake http://purl.obolibrary.org/obo/GO_0015677 GO:0015670 biolink:BiologicalProcess carbon dioxide transport The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015670 GO:0015671 biolink:BiologicalProcess oxygen transport The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015671 CHEBI:76101 biolink:ChemicalSubstance (S)-laudanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76101 GO:0015672 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015672 GO:0015673 biolink:BiologicalProcess silver ion transport The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json silver transport http://purl.obolibrary.org/obo/GO_0015673 CHEBI:76104 biolink:ChemicalSubstance kaempferol 3-O-beta-D-galactoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76104 chebi_ph7_3 GO:0039641 biolink:CellularComponent viral inner membrane The lipid bilayer of a virion contained inside the protein capsid. go-plus.json virion inner membrane http://purl.obolibrary.org/obo/GO_0039641 GO:1990336 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990336 GO:0039642 biolink:CellularComponent virion nucleoid The region of a virion in which the nucleic acid is confined. go-plus.json http://purl.obolibrary.org/obo/GO_0039642 GO:1990337 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990337 CHEBI:76105 biolink:ChemicalSubstance (R)-laudanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76105 CHEBI:76102 biolink:ChemicalSubstance laudanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76102 chebi_ph7_3 GO:1990338 biolink:CellularComponent laminin-14 complex A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains. go-plus.json laminin-423 http://purl.obolibrary.org/obo/GO_1990338 GO:0039640 biolink:BiologicalProcess viral release by cytolysis via suppression of host peptidoglycan biosynthetic process The killing by a virus of host cell by cytolysis, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls. go-plus.json cytolysis by virus via suppression of host peptidoglycan biosynthetic process|viral exit by cytolysis via suppression of host peptidoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0039640 GO:1990339 biolink:CellularComponent laminin-522 complex A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains. go-plus.json laminin-522 http://purl.obolibrary.org/obo/GO_1990339 CHEBI:76103 biolink:ChemicalSubstance laudanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76103 GO:0001048 biolink:MolecularActivity RNA polymerase IV core binding Binding to RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production. go-plus.json http://purl.obolibrary.org/obo/GO_0001048 GO:1990343 biolink:CellularComponent heterochromatin domain A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me). go-plus.json HOOD http://purl.obolibrary.org/obo/GO_1990343 GO:1990344 biolink:BiologicalProcess secondary cell septum biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division. go-plus.json http://purl.obolibrary.org/obo/GO_1990344 GO:0001049 biolink:MolecularActivity RNA polymerase V core binding Binding to RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing. go-plus.json http://purl.obolibrary.org/obo/GO_0001049 GO:1990345 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990345 GO:1990346 biolink:CellularComponent BID-BCL-xl complex A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_1990346 GO:0001044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001044 GO:1990340 biolink:CellularComponent laminin-15 complex A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains. go-plus.json laminin-523 http://purl.obolibrary.org/obo/GO_1990340 GO:0001045 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001045 GO:0001046 biolink:MolecularActivity core promoter sequence-specific DNA binding Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon. go-plus.json core promoter binding http://purl.obolibrary.org/obo/GO_0001046 GO:1990341 biolink:CellularComponent thrombospondin complex A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour. go-plus.json http://purl.obolibrary.org/obo/GO_1990341 GO:0001047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001047 GO:1990342 biolink:CellularComponent heterochromatin island A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi. go-plus.json http://purl.obolibrary.org/obo/GO_1990342 GO:0001040 biolink:MolecularActivity obsolete RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. go-plus.json http://purl.obolibrary.org/obo/GO_0001040 GO:0001041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001041 GO:0001042 biolink:MolecularActivity RNA polymerase I core binding Binding to a RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0001042 GO:0001043 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001043 GO:0039634 biolink:BiologicalProcess killing by virus of host cell during superinfection exclusion The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus. go-plus.json killing by virus of host cells involved in superinfection exclusion|Rex exclusion|killing by virus of host cells during superinfection exclusion http://purl.obolibrary.org/obo/GO_0039634 GO:0015689 biolink:BiologicalProcess molybdate ion transport The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0015689 GO:0039635 biolink:BiologicalProcess suppression by virus of host peptidoglycan biosynthetic process Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls. go-plus.json viral inhibition of host peptidoglycan biosynthesis http://purl.obolibrary.org/obo/GO_0039635 GO:0039632 biolink:MolecularActivity RNA translocase activity involved in viral RNA genome packaging Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid. go-plus.json viral RNA packaging activity|RNA packaging ATPase activity http://purl.obolibrary.org/obo/GO_0039632 GO:0039633 biolink:BiologicalProcess killing by virus of host cell Any process mediated by a virus that results in the death of a cell in the host organism. go-plus.json killing by phage of host cells|killing by virus of host cells http://purl.obolibrary.org/obo/GO_0039633 GO:0015685 biolink:BiologicalProcess ferric-enterobactin import into cell A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors. go-plus.json ferric-enterobactin transport http://purl.obolibrary.org/obo/GO_0015685 GO:0039638 biolink:BiologicalProcess lipopolysaccharide-mediated virion attachment to host cell The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface. go-plus.json virion attachment, binding to host lipopolysaccharide|LPS binding involved in viral attachment to host cell|lipopolysaccharide binding involved in viral attachment to host cell http://purl.obolibrary.org/obo/GO_0039638 GO:0015686 biolink:BiologicalProcess ferric triacetylfusarinine C import into cell The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json ferric triacetylfusarinine C transport http://purl.obolibrary.org/obo/GO_0015686 GO:0039639 biolink:BiologicalProcess suppression by virus of host cell lysis in response to superinfection The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus. go-plus.json lysis inhibition|suppression by virus of host cell lysis in response to superinfecting virus http://purl.obolibrary.org/obo/GO_0039639 CHEBI:134339 biolink:ChemicalSubstance 2-acyl-4-prenylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_134339 GO:0015687 biolink:BiologicalProcess ferric-hydroxamate import into cell A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors. go-plus.json ferric-hydroxamate transport http://purl.obolibrary.org/obo/GO_0015687 GO:0039636 biolink:BiologicalProcess suppression by virus of host cell wall biogenesis Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0039636 GO:0039637 biolink:BiologicalProcess catabolism by virus of host DNA The breakdown of host DNA, deoxyribonucleic acid, by a virus. go-plus.json http://purl.obolibrary.org/obo/GO_0039637 GO:0015688 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015688 GO:0015681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015681 GO:0015682 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015682 GO:0015683 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015683 GO:0015684 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015684 GO:1990347 biolink:MolecularActivity obsolete G*/A mismatch-specific adenine-DNA glycosylase activity OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite 8-oxoG in the template by adenine DNA glycosylase activity. The reaction leaves an apyrimidinic (AP) site. go-plus.json G*/A mismatch-specific adenine-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_1990347 GO:0039630 biolink:MolecularActivity RNA translocase activity Generating a movement along a single- or double-stranded RNA molecule, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0039630 GO:1990348 biolink:MolecularActivity obsolete G/A mismatch specific adenine DNA glycosylase activity OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite guanine in the template by adenine DNA glycosylase activity. The reaction leaves an apurinic AP site. I also requested same term but for Go/A mismatch. If you think it is better to make one term for mismatched adenine that is fine by me. go-plus.json G/A mismatch specific adenine DNA glycosylase activity http://purl.obolibrary.org/obo/GO_1990348 GO:0039631 biolink:MolecularActivity DNA translocase activity involved in viral DNA genome packaging Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid. go-plus.json viral DNA packaging motor activity|viral DNA packaging activity http://purl.obolibrary.org/obo/GO_0039631 BFO:0000141 biolink:OntologyClass immaterial entity go-plus.json http://purl.obolibrary.org/obo/BFO_0000141 GO:1990349 biolink:BiologicalProcess gap junction-mediated intercellular transport The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990349 GO:0015680 biolink:BiologicalProcess protein maturation by copper ion transfer A process that contributes to the delivery of copper ions to a target protein. go-plus.json intracellular copper delivery|intracellular copper ion transport|intracellular copper ion delivery http://purl.obolibrary.org/obo/GO_0015680 CHEBI:17709 biolink:ChemicalSubstance 5'-adenylyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17709 CHEBI:17707 biolink:ChemicalSubstance glucuronoxylan D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17707 CHEBI:17708 biolink:ChemicalSubstance 1,6-dihydroxycyclohexa-2,4-dienecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17708 chebi_ph7_3 CHEBI:17705 biolink:ChemicalSubstance N(2)-succinyl-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17705 CHEBI:17706 biolink:ChemicalSubstance Renilla luciferyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17706 CHEBI:17703 biolink:ChemicalSubstance 26-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17703 chebi_ph7_3 CHEBI:17704 biolink:ChemicalSubstance aspulvinone E go-plus.json http://purl.obolibrary.org/obo/CHEBI_17704 CHEBI:17701 biolink:ChemicalSubstance benzenediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17701 CHEBI:17702 biolink:ChemicalSubstance D-apiitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17702 chebi_ph7_3 CHEBI:17700 biolink:ChemicalSubstance undecan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17700 chebi_ph7_3 CHEBI:17729 biolink:ChemicalSubstance (S)-norcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17729 CHEBI:17727 biolink:ChemicalSubstance phorbol 13-butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17727 chebi_ph7_3 CHEBI:17728 biolink:ChemicalSubstance S-methyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17728 CHEBI:17725 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17725 CHEBI:17726 biolink:ChemicalSubstance [Glu(-Cys)]n-Gly go-plus.json http://purl.obolibrary.org/obo/CHEBI_17726 CHEBI:17723 biolink:ChemicalSubstance beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_17723 chebi_ph7_3 CHEBI:17724 biolink:ChemicalSubstance N,N-dimethylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17724 CHEBI:17721 biolink:ChemicalSubstance (S,S,S)-nicotianamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17721 CHEBI:17720 biolink:ChemicalSubstance 2,3-bisphospho-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17720 GO:1990300 biolink:MolecularActivity cellulosome binding Binding to a cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides. go-plus.json scaffoldin complex binding http://purl.obolibrary.org/obo/GO_1990300 GO:1990301 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990301 GO:1990302 biolink:CellularComponent Bre1-Rad6 ubiquitin ligase complex A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis. go-plus.json Bre1-Rad6 complex http://purl.obolibrary.org/obo/GO_1990302 CHEBI:17719 biolink:ChemicalSubstance beta-D-glucose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17719 CHEBI:17716 biolink:ChemicalSubstance lactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_17716 chebi_ph7_3 CHEBI:17717 biolink:ChemicalSubstance sulfoacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_17717 CHEBI:17715 biolink:ChemicalSubstance quinoline-2,8-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17715 chebi_ph7_3 CHEBI:17712 biolink:ChemicalSubstance 9H-xanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17712 chebi_ph7_3 CHEBI:17713 biolink:ChemicalSubstance 2'-deoxyadenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17713 CHEBI:17710 biolink:ChemicalSubstance (R)-mevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17710 CHEBI:17711 biolink:ChemicalSubstance nocardicin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_17711 GO:1990307 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990307 GO:1990308 biolink:MolecularActivity type-I dockerin domain binding Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain. go-plus.json http://purl.obolibrary.org/obo/GO_1990308 GO:1990309 biolink:MolecularActivity type-II dockerin domain binding Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain. go-plus.json http://purl.obolibrary.org/obo/GO_1990309 GO:1990303 biolink:CellularComponent UBR1-RAD6 ubiquitin ligase complex A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes. go-plus.json UBR1-RAD6 complex http://purl.obolibrary.org/obo/GO_1990303 GO:1990304 biolink:CellularComponent MUB1-RAD6-UBR2 ubiquitin ligase complex A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_1990304 GO:1990305 biolink:CellularComponent RAD6-UBR2 ubiquitin ligase complex A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation. go-plus.json RAD6-UBR2 complex http://purl.obolibrary.org/obo/GO_1990305 GO:1990306 biolink:CellularComponent RSP5-BUL ubiquitin ligase complex A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation. go-plus.json RSP5-BUL1 complex|RSP5-BUL2 complex http://purl.obolibrary.org/obo/GO_1990306 NCBITaxon:5820 biolink:OrganismalEntity Plasmodium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5820 NCBITaxon:5833 biolink:OrganismalEntity Plasmodium falciparum go-plus.json malaria parasite P. falciparum|Plasmodium (Laverania) falciparum http://purl.obolibrary.org/obo/NCBITaxon_5833 NCBITaxon:5819 biolink:OrganismalEntity Haemosporida go-plus.json Haemospororida|Haemosporina|haemosporidians http://purl.obolibrary.org/obo/NCBITaxon_5819 GO:0050147 biolink:MolecularActivity nucleoside ribosyltransferase activity Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1. MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.5 go-plus.json nucleoside:purine(pyrimidine) D-ribosyltransferase activity|nucleoside N-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0050147 CHEBI:27119 biolink:ChemicalSubstance trihydroxytoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27119 GO:0050148 biolink:MolecularActivity nucleotide diphosphokinase activity Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate. RHEA:12713|EC:2.7.6.4|MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN go-plus.json ATP:nucleotide pyrophosphotransferase activity|nucleotide pyrophosphokinase activity|ATP nucleotide 3'-pyrophosphokinase activity|nucleotide 3'-pyrophosphokinase activity|ATP:nucleoside-5'-phosphate diphosphotransferase activity http://purl.obolibrary.org/obo/GO_0050148 GO:0050145 biolink:MolecularActivity nucleoside monophosphate kinase activity Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate. Reactome:R-HSA-75125|MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN|Reactome:R-HSA-6788798|Reactome:R-HSA-6788810|Reactome:R-HSA-73635|EC:2.7.4.4|RHEA:24036|Reactome:R-HSA-2162092|Reactome:R-HSA-75126|Reactome:R-HSA-73548 go-plus.json nucleotide kinase activity|NMP-kinase activity|nucleoside-phosphate kinase activity|nucleoside monophosphate kinase activity|ATP:nucleoside-phosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050145 GO:0050146 biolink:MolecularActivity nucleoside phosphotransferase activity Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate. MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN|Reactome:R-HSA-2162066|EC:2.7.1.77|RHEA:19961 go-plus.json nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity|nonspecific nucleoside phosphotransferase activity|nucleotide:nucleoside 5'-phosphotransferase activity|nucleotide:2'-nucleoside 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050146 CHEBI:27115 biolink:ChemicalSubstance trihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27115 CHEBI:27116 biolink:ChemicalSubstance trihydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27116 GO:0050149 biolink:MolecularActivity o-aminophenol oxidase activity Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O. RHEA:40963|MetaCyc:O-AMINOPHENOL-OXIDASE-RXN|EC:1.10.3.4 go-plus.json isophenoxazine synthase activity|GriF|o-aminophenol:O2 oxidoreductase activity|2-aminophenol:O2 oxidoreductase activity|2-aminophenol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050149 CHEBI:27118 biolink:ChemicalSubstance naphthalenetriol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27118 GO:0015818 biolink:BiologicalProcess isoleucine transport The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-isoleucine transport http://purl.obolibrary.org/obo/GO_0015818 CL:0000644 biolink:Cell Bergmann glial cell Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. go-plus.json Bergmann astrocyte|Bergmann glial cell of cerebellum http://purl.obolibrary.org/obo/CL_0000644 GO:0015819 biolink:BiologicalProcess lysine transport The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json lysine import|L-lysine import|lysine uptake|L-lysine transport http://purl.obolibrary.org/obo/GO_0015819 CL:0000646 biolink:Cell basal cell Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. go-plus.json http://purl.obolibrary.org/obo/CL_0000646 CL:0000647 biolink:Cell multinucleated giant cell A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. go-plus.json foreign body giant cell|macrophage polykaryon|multinucleate giant cell|Langerhans giant cell|syncytial giant cell http://purl.obolibrary.org/obo/CL_0000647 CHEBI:27114 biolink:ChemicalSubstance trihydroxy-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27114 CL:0000648 biolink:Cell kidney granular cell A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. go-plus.json renin secreting cell|JG cell|juxtaglomerular cell http://purl.obolibrary.org/obo/CL_0000648 GO:0015814 biolink:BiologicalProcess p-aminobenzoyl-glutamate transport The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015814 UBERON:0010543 biolink:AnatomicalEntity acropodial skeleton The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the autopodium - i.e. the bones of the digits or their cartilaginous precursors[VSAO,modified]. go-plus.json acropodial skeleton|set of phalanges|skeletal parts of acropodium|skeleton of digits|acropodium|acropodium skeleton|digital skeleton|phalangeal skeleton|skeletal parts of acropodial region|digits skeleton http://purl.obolibrary.org/obo/UBERON_0010543 GO:0015815 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015815 GO:0015816 biolink:BiologicalProcess glycine transport The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015816 UBERON:0010540 biolink:AnatomicalEntity tarsus pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a tarsal bone. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010540 UBERON:0010541 biolink:AnatomicalEntity tarsus cartilage element A cartilaginous condensation that has the potential to develop into a tarsal bone. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010541 GO:0015817 biolink:BiologicalProcess histidine transport The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-histidine transport http://purl.obolibrary.org/obo/GO_0015817 CHEBI:76081 biolink:ChemicalSubstance 2'-phospho-cyclic ADP-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_76081 GO:0015810 biolink:BiologicalProcess aspartate transmembrane transport The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json mitochondrial aspartate/glutamate transport|aspartate transport http://purl.obolibrary.org/obo/GO_0015810 UBERON:0010535 biolink:AnatomicalEntity primitive metanephric nephron A primitive nephron that is part of a metanephros. go-plus.json primitive metanephric nephron|developing metanephric nephron|primitive nephron http://purl.obolibrary.org/obo/UBERON_0010535 UBERON:0010536 biolink:AnatomicalEntity nephron progenitor go-plus.json http://purl.obolibrary.org/obo/UBERON_0010536 GO:0015811 biolink:BiologicalProcess L-cystine transport The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015811 UBERON:0009559 biolink:AnatomicalEntity metacarpal/tarsal-phalangeal joint A skeletal joint that connects a mesopodium bone and connects a proximal phalanx. go-plus.json metapodium-phalanx joint|metacarpo-tarsophalangeal joint|fetlock|metapodial-phalangeal joint http://purl.obolibrary.org/obo/UBERON_0009559 GO:0015812 biolink:BiologicalProcess gamma-aminobutyric acid transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json 4-aminobutanoate transport|4-aminobutyrate transport|GABA transport http://purl.obolibrary.org/obo/GO_0015812 UBERON:0010533 biolink:AnatomicalEntity metanephros cortex The metanephric cortex is the outer region of the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010533 UBERON:0010534 biolink:AnatomicalEntity primitive mesonephric nephron Anatomical cluster which give rise to mature mesonephric nephrons. Zebrafish continously generate new mesonephric nephrons. go-plus.json primitive mesonephric nephron|developing mesonephric nephron http://purl.obolibrary.org/obo/UBERON_0010534 GO:0015813 biolink:BiologicalProcess L-glutamate transmembrane transport The directed movement of L-glutamate across a membrane. go-plus.json mitochondrial aspartate/glutamate transport|L-glutamate transport http://purl.obolibrary.org/obo/GO_0015813 CHEBI:76080 biolink:ChemicalSubstance 1-O-arachidonoyl-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76080 chebi_ph7_3 CHEBI:76085 biolink:ChemicalSubstance 2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76085 chebi_ph7_3 CHEBI:17789 biolink:ChemicalSubstance dihydrochelirubine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17789 chebi_ph7_3 CHEBI:76086 biolink:ChemicalSubstance 1-O-linoleoyl-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76086 chebi_ph7_3 CHEBI:76083 biolink:ChemicalSubstance oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76083 chebi_ph7_3 UBERON:0010537 biolink:AnatomicalEntity mesonephric nephron progenitor Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010537 CHEBI:76084 biolink:ChemicalSubstance 2-linoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76084 chebi_ph7_3 UBERON:0010538 biolink:AnatomicalEntity paired limb/fin segment An appendage segment that is part of a limb/fin. go-plus.json limb/fin segment http://purl.obolibrary.org/obo/UBERON_0010538 GO:0050140 biolink:MolecularActivity nitrate reductase (cytochrome) activity Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite. EC:1.9.6.1|MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN|RHEA:12909 go-plus.json ferrocytochrome:nitrate oxidoreductase activity|benzyl viologen-nitrate reductase activity http://purl.obolibrary.org/obo/GO_0050140 UBERON:0009550 biolink:AnatomicalEntity endoderm of foregut-midgut junction An endoderm that is part of a foregut-midgut junction. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009550 CHEBI:17786 biolink:ChemicalSubstance N-acetyl-L-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17786 CHEBI:76087 biolink:ChemicalSubstance 1-O-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76087 chebi_ph7_3 UBERON:0009551 biolink:AnatomicalEntity distal segment of digit A segment of a digit containing the distal phalanx, and overlapping the distal interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium). go-plus.json distal digit segment|tip of digit|digit tip http://purl.obolibrary.org/obo/UBERON_0009551 UBERON:0009552 biolink:AnatomicalEntity distal segment of manual digit A segment of the manual digit containing the distal phalanx go-plus.json finger tip|finger distal segment|forelimb digit tip|fingertip|finger digit tip|tip of finger http://purl.obolibrary.org/obo/UBERON_0009552 CHEBI:76088 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76088 chebi_ph7_3 CHEBI:17784 biolink:ChemicalSubstance 2-amino-2-deoxy-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17784 UBERON:0009553 biolink:AnatomicalEntity distal segment of pedal digit A segment of the pedal digit containing the distal phalanx. Note this class represents a digit segment and thus includes tissues in addition to bone. go-plus.json P3 segment of pedal digit|distalmost part of toe|toe distal segment|toe digit tip|hindlimb digit tip|tip of toe http://purl.obolibrary.org/obo/UBERON_0009553 GO:0050143 biolink:MolecularActivity nocardicin-A epimerase activity Catalysis of the reaction: isonocardicin A = nocardicin A. EC:5.1.1.14|RHEA:22792|KEGG_REACTION:R03073|MetaCyc:NOCARDICIN-A-EPIMERASE-RXN go-plus.json isonocardicin A epimerase activity http://purl.obolibrary.org/obo/GO_0050143 CHEBI:17781 biolink:ChemicalSubstance lumichrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_17781 chebi_ph7_3 GO:0050144 biolink:MolecularActivity nucleoside deoxyribosyltransferase activity Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1. EC:2.4.2.6|MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN go-plus.json purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity|trans-deoxyribosylase activity|trans-N-deoxyribosylase activity|nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]|trans-N-glycosidase activity|nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity|nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)|nucleoside trans-N-deoxyribosylase activity|deoxyribose transferase activity http://purl.obolibrary.org/obo/GO_0050144 CHEBI:17782 biolink:ChemicalSubstance 5-dehydro-4-deoxy-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17782 GO:0050141 biolink:MolecularActivity nitroethane oxidase activity Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2. EC:1.7.3.1|MetaCyc:NITROETHANE-OXIDASE-RXN go-plus.json nitroethane:oxygen oxidoreductase activity|nitroethane reductase activity http://purl.obolibrary.org/obo/GO_0050141 CHEBI:17780 biolink:ChemicalSubstance 5-hydroxy-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_17780 GO:0050142 biolink:MolecularActivity nitrogenase (flavodoxin) activity Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate. EC:1.19.6.1|RHEA:15645|MetaCyc:NITROGENASE-FLAVODOXIN-RXN go-plus.json reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing) http://purl.obolibrary.org/obo/GO_0050142 GO:0050158 biolink:MolecularActivity orotate reductase (NADPH) activity Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate. RHEA:14861|MetaCyc:OROTATE-REDUCTASE-NADPH-RXN|EC:1.3.1.15|KEGG_REACTION:R01866 go-plus.json L-5,6-dihydro-orotate:NAD oxidoreductase activity|orotate reductase activity|(S)-dihydroorotate:NADP+ oxidoreductase activity|dihydro-orotic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050158 GO:0050159 biolink:MolecularActivity orsellinate decarboxylase activity Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol. RHEA:16733|MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN|EC:4.1.1.58|KEGG_REACTION:R02831 go-plus.json orsellinate carboxy-lyase (orcinol-forming)|orsellinate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0050159 GO:0050156 biolink:MolecularActivity ornithine N-benzoyltransferase activity Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+). EC:2.3.1.127|MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN|RHEA:16929|KEGG_REACTION:R00664 go-plus.json ornithine N-acyltransferase activity|benzoyl-CoA:L-ornithine N-benzoyltransferase activity http://purl.obolibrary.org/obo/GO_0050156 GO:0050157 biolink:MolecularActivity ornithine racemase activity Catalysis of the reaction: L-ornithine = D-ornithine. RHEA:11584|MetaCyc:ORNITHINE-RACEMASE-RXN|EC:5.1.1.12 go-plus.json http://purl.obolibrary.org/obo/GO_0050157 NCBITaxon:5878 biolink:OrganismalEntity Ciliophora go-plus.json Ciliata|ciliates|ciliates http://purl.obolibrary.org/obo/NCBITaxon_5878 GO:0015829 biolink:BiologicalProcess valine transport The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-valine transport http://purl.obolibrary.org/obo/GO_0015829 CL:0000655 biolink:Cell secondary oocyte A secondary oocyte is an oocyte that has not completed meiosis II. go-plus.json primary oogonium http://purl.obolibrary.org/obo/CL_0000655 CL:0000656 biolink:Cell primary spermatocyte A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. go-plus.json http://purl.obolibrary.org/obo/CL_0000656 CL:0000657 biolink:Cell secondary spermatocyte One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. go-plus.json http://purl.obolibrary.org/obo/CL_0000657 CHEBI:27124 biolink:ChemicalSubstance trimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_27124 UBERON:0010531 biolink:AnatomicalEntity metanephros induced blastemal cells . go-plus.json cap mesenchyme of metanephros of urinary system|induced blastemal cells|peripheral blastema|nephrogenic interstitium|nephrogenic interstitium of nephrogenic zone http://purl.obolibrary.org/obo/UBERON_0010531 GO:0015825 biolink:BiologicalProcess L-serine transport The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-serine import http://purl.obolibrary.org/obo/GO_0015825 UBERON:0010532 biolink:AnatomicalEntity primitive nephron An epithelial tube that is fated to become a nephron. go-plus.json presumptive nephron|future nephron|primitive nephron|developing nephron http://purl.obolibrary.org/obo/UBERON_0010532 GO:0015826 biolink:BiologicalProcess threonine transport The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-threonine transport http://purl.obolibrary.org/obo/GO_0015826 GO:0015827 biolink:BiologicalProcess tryptophan transport The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-tryptophan transport http://purl.obolibrary.org/obo/GO_0015827 CHEBI:27120 biolink:ChemicalSubstance triihydroxypyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_27120 GO:0015828 biolink:BiologicalProcess tyrosine transport The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-tyrosine transport http://purl.obolibrary.org/obo/GO_0015828 GO:0015821 biolink:BiologicalProcess methionine transport The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-methionine transport http://purl.obolibrary.org/obo/GO_0015821 GO:0015822 biolink:BiologicalProcess ornithine transport The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-ornithine transport http://purl.obolibrary.org/obo/GO_0015822 UBERON:0009548 biolink:AnatomicalEntity hepatic sinusoid of left of lobe of liver A hepatic sinusoid that is part of a left lobe of liver. go-plus.json left lobe hepatic sinusoids http://purl.obolibrary.org/obo/UBERON_0009548 UBERON:0010522 biolink:AnatomicalEntity replacement element Skeletal element that forms as a replacement or substitution of another element or tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0010522 GO:0015823 biolink:BiologicalProcess phenylalanine transport The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-phenylalanine transport http://purl.obolibrary.org/obo/GO_0015823 CHEBI:76090 biolink:ChemicalSubstance 2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76090 chebi_ph7_3 CL:0000650 biolink:Cell mesangial cell A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. go-plus.json kidney mesangial cell http://purl.obolibrary.org/obo/CL_0000650 UBERON:0010523 biolink:AnatomicalEntity microcirculatory vessel A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. go-plus.json microcirculatory vessels http://purl.obolibrary.org/obo/UBERON_0010523 GO:0015824 biolink:BiologicalProcess proline transport The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-proline transport http://purl.obolibrary.org/obo/GO_0015824 UBERON:0009549 biolink:AnatomicalEntity hepatic sinusoid of right of lobe of liver A hepatic sinusoid that is part of a right lobe of liver. go-plus.json right lobe hepatic sinusoids http://purl.obolibrary.org/obo/UBERON_0009549 CHEBI:76091 biolink:ChemicalSubstance 2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76091 chebi_ph7_3 UBERON:0010528 biolink:AnatomicalEntity pneumatic cavity of bone go-plus.json air space of bone http://purl.obolibrary.org/obo/UBERON_0010528 CHEBI:17778 biolink:ChemicalSubstance 2-hydroxy-3-oxosuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17778 CL:0000653 biolink:Cell glomerular visceral epithelial cell A glomerular visceral epithelial cell is a specialized kidney epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells. go-plus.json epithelial cell of visceral layer of glomerular capsule|glomerular podocyte|podocyte http://purl.obolibrary.org/obo/CL_0000653 GO:0015820 biolink:BiologicalProcess leucine transport The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-leucine transport http://purl.obolibrary.org/obo/GO_0015820 UBERON:0010527 biolink:AnatomicalEntity cavity of bone organ An organ cavity that surrounded_by a bone. go-plus.json bone organ cavity http://purl.obolibrary.org/obo/UBERON_0010527 CL:0000654 biolink:Cell primary oocyte A primary oocyte is an oocyte that has not completed female meosis I. go-plus.json primary oogonium http://purl.obolibrary.org/obo/CL_0000654 GO:0050150 biolink:MolecularActivity o-pyrocatechuate decarboxylase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2). MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN|UM-BBD_reactionID:r0579|EC:4.1.1.46|KEGG_REACTION:R00821|RHEA:21492 go-plus.json 2,3-dihydroxybenzoic acid decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase activity|2,3-dihydroxybenzoate decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)|2,3-DHBA decarboxylase activity http://purl.obolibrary.org/obo/GO_0050150 CHEBI:17774 biolink:ChemicalSubstance pimelate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17774 GO:0050151 biolink:MolecularActivity oleate hydratase activity Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate. KEGG_REACTION:R02813|RHEA:21852|EC:4.2.1.53|MetaCyc:OLEATE-HYDRATASE-RXN go-plus.json (R)-10-hydroxystearate 10-hydro-lyase activity|(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming) http://purl.obolibrary.org/obo/GO_0050151 CHEBI:17775 biolink:ChemicalSubstance 7,9-dihydro-1H-purine-2,6,8(3H)-trione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17775 chebi_ph7_3 CHEBI:17772 biolink:ChemicalSubstance (S)-tetrahydrocolumbamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17772 chebi_ph7_3 CHEBI:17773 biolink:ChemicalSubstance D-ribonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17773 chebi_ph7_3 CHEBI:76099 biolink:ChemicalSubstance phenyl 5-phosphono-alpha-D-ribofuranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_76099 GO:0050154 biolink:MolecularActivity opheline kinase activity Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+). MetaCyc:OPHELINE-KINASE-RXN|RHEA:17553|EC:2.7.3.7|KEGG_REACTION:R04388 go-plus.json ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050154 CHEBI:17770 biolink:ChemicalSubstance 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17770 chebi_ph7_3 GO:0050155 biolink:MolecularActivity ornithine(lysine) transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate. MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN|EC:2.6.1.13 go-plus.json ornithine(lysine) aminotransferase activity|lysine/ornithine:2-oxoglutarate aminotransferase activity|L-ornithine:2-oxoglutarate-aminotransferase activity|L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity http://purl.obolibrary.org/obo/GO_0050155 CHEBI:17771 biolink:ChemicalSubstance trans-urocanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17771 chebi_ph7_3 GO:0050152 biolink:MolecularActivity omega-amidase activity Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3. EC:3.5.1.3|RHEA:11716|MetaCyc:OMEGA-AMIDASE-RXN go-plus.json w-amidase activity|omega-amidodicarboxylate amidohydrolase activity|alpha-keto acid-omega-amidase activity http://purl.obolibrary.org/obo/GO_0050152 GO:0050153 biolink:MolecularActivity omega-hydroxydecanoate dehydrogenase activity Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH. MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN|EC:1.1.1.66|KEGG_REACTION:R03886|RHEA:20880 go-plus.json w-hydroxydecanoate dehydrogenase activity|10-hydroxydecanoate:NAD+ 10-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050153 GO:0050169 biolink:MolecularActivity peptide-tryptophan 2,3-dioxygenase activity Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine. MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN|EC:1.13.11.26 go-plus.json pyrrolooxygenase activity|peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|tryptophan pyrrolooxygenase activity|peptidyltryptophan 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0050169 GO:0050167 biolink:MolecularActivity pantothenoylcysteine decarboxylase activity Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2). EC:4.1.1.30|KEGG_REACTION:R02972|MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN|RHEA:15077 go-plus.json N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)|pantothenylcysteine decarboxylase activity|N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity|N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0050167 GO:0050168 biolink:MolecularActivity pentanamidase activity Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate. KEGG_REACTION:R02938|MetaCyc:PENTANAMIDASE-RXN|RHEA:10000|EC:3.5.1.50 go-plus.json valeramidase activity|pentanamide amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050168 CL:0000622 biolink:Cell acinar cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). go-plus.json acinous cell|acinic cell http://purl.obolibrary.org/obo/CL_0000622 CL:0000623 biolink:Cell natural killer cell A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. go-plus.json null cell|large granular lymphocyte|NK cell http://purl.obolibrary.org/obo/CL_0000623 CL:0000624 biolink:Cell CD4-positive, alpha-beta T cell A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. go-plus.json CD4-positive, alpha-beta T-cell|CD4-positive, alpha-beta T-lymphocyte|CD4-positive, alpha-beta T lymphocyte http://purl.obolibrary.org/obo/CL_0000624 CL:0000625 biolink:Cell CD8-positive, alpha-beta T cell A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. go-plus.json CD8-positive, alpha-beta T-cell|CD8-positive, alpha-beta T-lymphocyte|CD8-positive, alpha-beta T lymphocyte http://purl.obolibrary.org/obo/CL_0000625 CL:0000626 biolink:Cell olfactory granule cell Granule cell that is part of the olfactory bulb. go-plus.json http://purl.obolibrary.org/obo/CL_0000626 UBERON:0010521 biolink:AnatomicalEntity electroreceptor organ An organ that is capable of detecting electrical stimulus go-plus.json electric sense organ|electroreception organ http://purl.obolibrary.org/obo/UBERON_0010521 UBERON:0009536 biolink:AnatomicalEntity vascular element of left lung A vascular plexus that is part of a left lung. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009536 UBERON:0009537 biolink:AnatomicalEntity vascular element of right lung A vascular plexus that is part of a right lung. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009537 UBERON:0009539 biolink:AnatomicalEntity mesenchyme of submandibular gland primordium Mesenchyme that is part of a submandibular gland primordium. go-plus.json submaxillary gland primordium mesenchyme http://purl.obolibrary.org/obo/UBERON_0009539 GO:0050161 biolink:MolecularActivity succinyl-CoA:oxalate CoA-transferase Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate. KEGG_REACTION:R01559|RHEA:23588|MetaCyc:OXALATE-COA-TRANSFERASE-RXN|EC:2.8.3.2 go-plus.json succinyl-beta-ketoacyl-CoA transferase activity|oxalate coenzyme A-transferase activity|oxalate CoA-transferase activity|succinyl-CoA:oxalate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0050161 GO:0050162 biolink:MolecularActivity oxalate oxidase activity Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2). RHEA:21880|MetaCyc:OXALATE-OXIDASE-RXN|KEGG_REACTION:R00273|EC:1.2.3.4 go-plus.json oxalate:oxygen oxidoreductase activity|oxalic acid oxidase activity|aero-oxalo dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050162 GO:0050160 biolink:MolecularActivity orsellinate-depside hydrolase activity Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+). EC:3.1.1.40|RHEA:19549|KEGG_REACTION:R00054|MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN go-plus.json lecanorate hydrolase activity http://purl.obolibrary.org/obo/GO_0050160 GO:0050165 biolink:MolecularActivity pantetheine kinase activity Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate. EC:2.7.1.34|RHEA:22472|MetaCyc:PANTETHEINE-KINASE-RXN go-plus.json pantetheine kinase (phosphorylating)|ATP:pantetheine 4'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050165 GO:0050166 biolink:MolecularActivity pantoate 4-dehydrogenase activity Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH. MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN|RHEA:23000|KEGG_REACTION:R02471|EC:1.1.1.106 go-plus.json (R)-pantoate:NAD+ 4-oxidoreductase activity|pantoate dehydrogenase activity|panthothenase activity|D-pantoate:NAD+ 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050166 GO:0050163 biolink:MolecularActivity oxaloacetate tautomerase activity Catalysis of the reaction: oxaloacetate = enol-oxaloacetate. KEGG_REACTION:R00363|EC:5.3.2.2|RHEA:16021|MetaCyc:OXALOACETATE-TAUTOMERASE-RXN go-plus.json oxaloacetate keto-enol tautomerase activity|oxaloacetate keto-enol-isomerase activity|oxalacetic keto-enol isomerase activity http://purl.obolibrary.org/obo/GO_0050163 GO:0050164 biolink:MolecularActivity oxoglutarate dehydrogenase (NADP+) activity Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA. EC:1.2.1.52|RHEA:21400|KEGG_REACTION:R00265|MetaCyc:OXOGLUTARATE-DEHYDROGENASE-NADP+-RXN go-plus.json 2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating) http://purl.obolibrary.org/obo/GO_0050164 GO:0050178 biolink:MolecularActivity phenylpyruvate tautomerase activity Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate. EC:5.3.2.1|RHEA:17097|MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN go-plus.json phenylpyruvate keto--enol tautomerase activity|phenylpyruvic keto--enol isomerase activity|phenylpyruvate keto-enol-isomerase activity http://purl.obolibrary.org/obo/GO_0050178 GO:0050179 biolink:MolecularActivity phenylserine aldolase activity Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine. MetaCyc:PHENYLSERINE-ALDOLASE-RXN|EC:4.1.2.26|RHEA:21712|KEGG_REACTION:R01766 go-plus.json L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)|L-threo-3-phenylserine benzaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0050179 CHEBI:27105 biolink:ChemicalSubstance tridecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27105 GO:0015807 biolink:BiologicalProcess L-amino acid transport The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015807 GO:0015808 biolink:BiologicalProcess L-alanine transport The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015808 GO:0015809 biolink:BiologicalProcess arginine transport The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-arginine transport http://purl.obolibrary.org/obo/GO_0015809 CHEBI:27102 biolink:ChemicalSubstance trichlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27102 GO:0015803 biolink:BiologicalProcess branched-chain amino acid transport The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. go-plus.json branched-chain amino-acid anion transport|branched-chain amino-acid anions transport|branched-chain aliphatic amino acid transport http://purl.obolibrary.org/obo/GO_0015803 CL:0000637 biolink:Cell chromophil cell of anterior pituitary gland A cell that stains readily in the anterior pituitary gland. go-plus.json http://purl.obolibrary.org/obo/CL_0000637 GO:0015804 biolink:BiologicalProcess neutral amino acid transport The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015804 CL:0000639 biolink:Cell basophil cell of pars distalis of adenohypophysis A basophillic chromophil cell that of the anterior pituitary gland. go-plus.json pituitary beta cell|basophil cell of anterior lobe of hypophysis|beta cell http://purl.obolibrary.org/obo/CL_0000639 GO:0015805 biolink:BiologicalProcess S-adenosyl-L-methionine transport The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json S-adenosylmethionine transport|SAM transport|S-adenosyl methionine transport http://purl.obolibrary.org/obo/GO_0015805 GO:0015806 biolink:BiologicalProcess S-methylmethionine transport The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015806 GO:0015800 biolink:BiologicalProcess acidic amino acid transport The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015800 UBERON:0009526 biolink:AnatomicalEntity maxillary process mesenchyme Mesenchyme that is part of a maxillary prominence. go-plus.json mesenchyme of maxillary process|mesenchyme of maxillary prominence http://purl.obolibrary.org/obo/UBERON_0009526 GO:0015801 biolink:BiologicalProcess aromatic amino acid transport The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015801 GO:0015802 biolink:BiologicalProcess basic amino acid transport The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015802 CHEBI:42724 biolink:ChemicalSubstance (R)-amphetamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_42724 CL:0000630 biolink:Cell supportive cell A cell whose primary function is to support other cell types. go-plus.json http://purl.obolibrary.org/obo/CL_0000630 CHEBI:17798 biolink:ChemicalSubstance L-gamma-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17798 CL:0000632 biolink:Cell hepatic stellate cell A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. go-plus.json lipocyte|Ito cell|perisinusoidal cell|hepatic perisinusoidal cell|fat-storing cell|vitamin A-storing cells http://purl.obolibrary.org/obo/CL_0000632 CHEBI:17799 biolink:ChemicalSubstance 2-methyl-DL-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17799 GO:0050172 biolink:MolecularActivity phenylalanine 2-monooxygenase activity Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O. EC:1.13.12.9|RHEA:10712|KEGG_REACTION:R00690|MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN go-plus.json L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)|l-phenylalanine oxidase (deaminating and decarboxylating) activity|phenylalanine (deaminating, decarboxylating) oxidase activity|L-phenylalanine oxidase (deaminating and decarboxylating)|phenylalanine (deaminating, decarboxylating)oxidase activity http://purl.obolibrary.org/obo/GO_0050172 CHEBI:17796 biolink:ChemicalSubstance L-idonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17796 chebi_ph7_3 GO:0050173 biolink:MolecularActivity phenylalanine adenylyltransferase activity Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+). KEGG_REACTION:R00687|MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.54|RHEA:17189 go-plus.json ATP:phenylalanine adenylyltransferase activity|L-phenylalanine adenylyltransferase activity|ATP:L-phenylalanine adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0050173 CHEBI:17797 biolink:ChemicalSubstance aldehydo-D-ribose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17797 NCBITaxon:88770 biolink:OrganismalEntity Panarthropoda go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_88770 GO:0050170 biolink:MolecularActivity peptidyl-glutaminase activity Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3. EC:3.5.1.43|RHEA:10032|MetaCyc:PEPTIDYL-GLUTAMINASE-RXN go-plus.json peptideglutaminase activity|peptidoglutaminase I activity|peptidoglutaminase activity|peptidyl-L-glutamine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050170 CHEBI:17794 biolink:ChemicalSubstance 3-phospho-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17794 GO:0050171 biolink:MolecularActivity phenol beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside. MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.35 go-plus.json phenol-beta-D-glucosyltransferase activity|UDPglucose:phenol beta-D-glucosyltransferase activity|phenol b-glucosyltransferase activity|UDPglucosyltransferase activity|UDP glucosyltransferase activity|uridine diphosphoglucosyltransferase activity|UDP-glucose glucosyltransferase activity|UDP-glucose:phenol beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050171 CHEBI:17795 biolink:ChemicalSubstance dihydroxyfumarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17795 chebi_ph7_3 GO:0050176 biolink:MolecularActivity phenylalanine N-acetyltransferase activity Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+). MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.53|RHEA:17801|KEGG_REACTION:R00693 go-plus.json acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity|acetyl-CoA:L-phenylalanine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050176 CHEBI:17792 biolink:ChemicalSubstance organohalogen compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_17792 chebi_ph7_3 GO:0050177 biolink:MolecularActivity phenylpyruvate decarboxylase activity Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2. MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN|RHEA:14185|EC:4.1.1.43 go-plus.json phenylpyruvate carboxy-lyase activity|phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming) http://purl.obolibrary.org/obo/GO_0050177 UBERON:0009521 biolink:AnatomicalEntity anal membrane endodermal component An endoderm that is part of a anal region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009521 CHEBI:17793 biolink:ChemicalSubstance calycosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17793 UBERON:0009522 biolink:AnatomicalEntity lateral lingual swelling epithelium An epithelium that is part of a lateral lingual swelling. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009522 CHEBI:17790 biolink:ChemicalSubstance methanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17790 chebi_ph7_3 GO:0050174 biolink:MolecularActivity phenylalanine decarboxylase activity Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2. MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN|EC:4.1.1.53|RHEA:19717 go-plus.json L-phenylalanine carboxy-lyase activity|aromatic L-amino acid decarboxylase activity|L-phenylalanine decarboxylase activity|L-phenylalanine carboxy-lyase (phenylethylamine-forming) http://purl.obolibrary.org/obo/GO_0050174 GO:0050175 biolink:MolecularActivity phenylalanine dehydrogenase activity Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH. MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN|RHEA:21408|EC:1.4.1.20 go-plus.json L-phenylalanine:NAD+ oxidoreductase (deaminating)|PheDH activity|PHD|L-phenylalanine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050175 UBERON:0009523 biolink:AnatomicalEntity mesenchyme of handplate Mesenchyme that is part of a handplate. go-plus.json hand plate mesenchyme|handplate mesenchyme http://purl.obolibrary.org/obo/UBERON_0009523 CHEBI:17791 biolink:ChemicalSubstance obtusifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17791 chebi_ph7_3 CL:0000608 biolink:Cell zygospore A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium. go-plus.json http://purl.obolibrary.org/obo/CL_0000608 CL:0000609 biolink:Cell vestibular hair cell A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. go-plus.json vestibular receptor cell http://purl.obolibrary.org/obo/CL_0000609 GO:0050189 biolink:MolecularActivity phosphoenolpyruvate phosphatase activity Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate. KEGG_REACTION:R00208|MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN|EC:3.1.3.60|RHEA:19997 go-plus.json PEP phosphatase activity|phosphoenolpyruvate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050189 CL:0000601 biolink:Cell outer hair cell A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. go-plus.json cochlear outer hair cell http://purl.obolibrary.org/obo/CL_0000601 CL:0000604 biolink:Cell retinal rod cell One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. go-plus.json http://purl.obolibrary.org/obo/CL_0000604 UBERON:0010586 biolink:AnatomicalEntity manual digit phalanx pre-cartilage condensation A pre-cartilage condensation that is part of a manual digit mesenchyme. go-plus.json fore limb digit phalanx pre-cartilage condensation|forelimb phalanx pre-cartilage condensation|hand phalanx pre-cartilage condensation|hand digit phalanx pre-cartilage condensation|manus phalanx pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010586 CL:0000605 biolink:Cell fungal asexual spore A spore formed following mitosis or mitoses. go-plus.json http://purl.obolibrary.org/obo/CL_0000605 CL:0000606 biolink:Cell macroconidium The larger of two types of asexual spores formed by some fungi; usually round or oblong. go-plus.json http://purl.obolibrary.org/obo/CL_0000606 CL:0000607 biolink:Cell ascospore A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete. go-plus.json http://purl.obolibrary.org/obo/CL_0000607 UBERON:0010585 biolink:AnatomicalEntity pedal digit phalanx pre-cartilage condensation A pre-cartilage condensation that is part of a pedal digit mesenchyme. go-plus.json pes phalanx pre-cartilage condensation|hind limb digit phalanx pre-cartilage condensation|hindlimb phalanx pre-cartilage condensation|foot phalanx pre-cartilage condensation|foot digit phalanx pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010585 CHEBI:42717 biolink:ChemicalSubstance alpha-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_42717 CHEBI:17747 biolink:ChemicalSubstance bis(2-ethylhexyl) phthalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17747 chebi_ph7_3 CHEBI:17748 biolink:ChemicalSubstance thymidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17748 chebi_ph7_3 CHEBI:17745 biolink:ChemicalSubstance coniferol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17745 chebi_ph7_3 CHEBI:17746 biolink:ChemicalSubstance D-xylonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17746 chebi_ph7_3 GO:0050180 biolink:MolecularActivity phloretin hydrolase activity Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol. EC:3.7.1.4|RHEA:23396|MetaCyc:PHLORETIN-HYDROLASE-RXN|KEGG_REACTION:R02901 go-plus.json 2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity|lactase-phlorizin hydrolase http://purl.obolibrary.org/obo/GO_0050180 GO:0050183 biolink:MolecularActivity phosphatidylcholine 12-monooxygenase activity Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+). KEGG_REACTION:R03476|RHEA:46360|EC:1.14.18.4|MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN go-plus.json ricinoleic acid synthase activity|oleate Delta(12)-hydroxylase activity|oleate delta12-hydroxylase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)|oleate delta12-monooxygenase activity|oleate D12-hydroxylase activity http://purl.obolibrary.org/obo/GO_0050183 CHEBI:17741 biolink:ChemicalSubstance N,N-dimethylformamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17741 chebi_ph7_3 GO:0050184 biolink:MolecularActivity phosphatidylcholine desaturase activity Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH. RHEA:12564|KEGG_REACTION:R03475|MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN|EC:1.14.19.22 go-plus.json acyl-lipid omega-6 desaturase (cytochrome b5)|linoleate synthase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity|oleoylphosphatidylcholine desaturase activity|oleate desaturase activity|oleoyl-CoA desaturase activity http://purl.obolibrary.org/obo/GO_0050184 CHEBI:17742 biolink:ChemicalSubstance 4-hydroxy-2-oxoglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17742 chebi_ph7_3 GO:0050181 biolink:MolecularActivity phorbol-diester hydrolase activity Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate. KEGG_REACTION:R04119|EC:3.1.1.51|MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN|RHEA:21316 go-plus.json diacylphorbate 12-hydrolase activity|12,13-diacylphorbate 12-acylhydrolase activity|PDEH|phorbol-12,13-diester 12-ester hydrolase activity http://purl.obolibrary.org/obo/GO_0050181 GO:0050182 biolink:MolecularActivity phosphate butyryltransferase activity Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA. RHEA:20892|KEGG_REACTION:R01174|EC:2.3.1.19|MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN go-plus.json phosphotransbutyrylase activity|butanoyl-CoA:phosphate butanoyltransferase activity http://purl.obolibrary.org/obo/GO_0050182 CHEBI:17740 biolink:ChemicalSubstance 3-oxoalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17740 GO:0050187 biolink:MolecularActivity phosphoamidase activity Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate. RHEA:12977|KEGG_REACTION:R01882|EC:3.9.1.1|MetaCyc:PHOSPHOAMIDASE-RXN go-plus.json phosphamide hydrolase activity|creatine phosphatase activity http://purl.obolibrary.org/obo/GO_0050187 GO:0050188 biolink:MolecularActivity phosphoenolpyruvate mutase activity Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate. EC:5.4.2.9|KEGG_REACTION:R00661|RHEA:17013|MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN go-plus.json PEP phosphomutase activity|phosphoenolpyruvate-phosphonopyruvate phosphomutase activity|phosphoenolpyruvate phosphomutase activity|PEP mutase activity|PEPPM|phosphoenolpyruvate 2,3-phosphonomutase activity http://purl.obolibrary.org/obo/GO_0050188 GO:0050185 biolink:MolecularActivity phosphatidylinositol deacylase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+). EC:3.1.1.52|KEGG_REACTION:R03360|MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN|RHEA:18001 go-plus.json 1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity|phosphatidylinositol phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0050185 GO:0050186 biolink:MolecularActivity phosphoadenylylsulfatase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate. RHEA:11232|EC:3.6.2.2|MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN go-plus.json 3'-phosphoadenylylsulfate sulfohydrolase activity|3-phosphoadenosine 5-phosphosulfate sulfatase activity|phosphoadenylylsulphatase activity|3-phosphoadenylyl sulfatase activity|PAPS sulfatase activity http://purl.obolibrary.org/obo/GO_0050186 UBERON:0009580 biolink:AnatomicalEntity diencephalon mantle layer go-plus.json mantle layer lateral wall diencephalon|diencephalon lateral wall mantle layer http://purl.obolibrary.org/obo/UBERON_0009580 UBERON:0009581 biolink:AnatomicalEntity midbrain mantle layer go-plus.json midbrain lateral wall mantle layer|mantle layer lateral wall midbrain|mantle layer lateral wall mesencephalon http://purl.obolibrary.org/obo/UBERON_0009581 CL:0000611 biolink:Cell eosinophil progenitor cell go-plus.json eosinophil stem cell|colony forming unit eosinophil|EoP|CFU-Eo http://purl.obolibrary.org/obo/CL_0000611 CL:0000612 biolink:Cell eosinophilic myelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0000612 CL:0000613 biolink:Cell basophil progenitor cell A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. go-plus.json BaP|colony forming unit basophil|basophilic stem cell|CFU-Bas http://purl.obolibrary.org/obo/CL_0000613 CL:0000614 biolink:Cell basophilic myelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0000614 CL:0000615 biolink:Cell basidiospore A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium. go-plus.json http://purl.obolibrary.org/obo/CL_0000615 CL:0000617 biolink:Cell GABAergic neuron A neuron that uses GABA as a vesicular neurotransmitter go-plus.json GABA-ergic neuron http://purl.obolibrary.org/obo/CL_0000617 CHEBI:17738 biolink:ChemicalSubstance N-methyl-2-oxoglutaramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17738 chebi_ph7_3 CHEBI:17736 biolink:ChemicalSubstance S-(4-bromophenyl)-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17736 CHEBI:17737 biolink:ChemicalSubstance desmosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17737 chebi_ph7_3 GO:0050190 biolink:MolecularActivity phosphoglucokinase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+). KEGG_REACTION:R00949|MetaCyc:PHOSPHOGLUCOKINASE-RXN|EC:2.7.1.10|RHEA:13377 go-plus.json ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity|phosphoglucokinase (phosphorylating)|glucose-phosphate kinase activity|ATP:D-glucose-1-phosphate 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050190 CHEBI:17734 biolink:ChemicalSubstance alpha-cyclopiazonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17734 GO:0050191 biolink:MolecularActivity phosphoglycerate kinase (GTP) activity Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+). KEGG_REACTION:R01517|MetaCyc:PHOSPHOGLYCERATE-KINASE-GTP-RXN|EC:2.7.2.10|RHEA:23332 go-plus.json GTP:3-phospho-D-glycerate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0050191 CHEBI:17735 biolink:ChemicalSubstance N,N-dimethylaniline N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17735 chebi_ph7_3 CHEBI:17732 biolink:ChemicalSubstance Ala-tRNA(Ala) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17732 CHEBI:17733 biolink:ChemicalSubstance aldehydo-D-galactose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17733 GO:0050194 biolink:MolecularActivity phosphonoacetaldehyde hydrolase activity Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate. MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN|EC:3.11.1.1|KEGG_REACTION:R00747|RHEA:18905 go-plus.json phosphonatase activity|2-phosphonoacetylaldehyde phosphonohydrolase activity|phosphonoacetylaldehyde phosphonohydrolase activity|2-oxoethylphosphonate phosphonohydrolase activity http://purl.obolibrary.org/obo/GO_0050194 CHEBI:17730 biolink:ChemicalSubstance quercetin 3-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17730 GO:0050195 biolink:MolecularActivity phosphoribokinase activity Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+). EC:2.7.1.18|RHEA:21216|MetaCyc:PHOSPHORIBOKINASE-RXN|KEGG_REACTION:R01050 go-plus.json ATP:D-ribose-5-phosphate 1-phosphotransferase activity|phosphoribokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0050195 UBERON:0009583 biolink:AnatomicalEntity spinal cord mantle layer go-plus.json spinal cord lateral wall mantle layer|mantle layer lateral wall spinal cord http://purl.obolibrary.org/obo/UBERON_0009583 GO:0050192 biolink:MolecularActivity phosphoglycerate phosphatase activity Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate. KEGG_REACTION:R01748|EC:3.1.3.20|RHEA:21156|MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN go-plus.json glycerophosphate phosphatase activity|D-glycerate-2-phosphate phosphohydrolase activity|D-2-phosphoglycerate phosphatase activity http://purl.obolibrary.org/obo/GO_0050192 UBERON:0009584 biolink:AnatomicalEntity 1st arch mandibular mesenchyme Mesenchyme that is part of a 1st arch mandibular component. go-plus.json mandibular component mesenchyme|mesenchyme of mandibular component|mesenchymal region of mandibular component of first pharyngeal arch|mandibular mesenchyme http://purl.obolibrary.org/obo/UBERON_0009584 GO:0050193 biolink:MolecularActivity phosphoketolase activity Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. RHEA:10468|EC:4.1.2.9|MetaCyc:PHOSPHOKETOLASE-RXN go-plus.json D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity|D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|xylulose-5-phosphate phosphoketolase activity http://purl.obolibrary.org/obo/GO_0050193 GO:0050198 biolink:MolecularActivity pinosylvin synthase activity Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin. MetaCyc:PINOSYLVIN-SYNTHASE-RXN|KEGG_REACTION:R02505|RHEA:12552|EC:2.3.1.146 go-plus.json stilbene synthase activity|malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)|pine stilbene synthase activity http://purl.obolibrary.org/obo/GO_0050198 GO:0050199 biolink:MolecularActivity piperidine N-piperoyltransferase activity Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+). EC:2.3.1.145|MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN|KEGG_REACTION:R03994|RHEA:14561 go-plus.json piperoyl-CoA:piperidine N-piperoyltransferase activity|(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity|piperidine piperoyltransferase activity http://purl.obolibrary.org/obo/GO_0050199 GO:0050196 biolink:MolecularActivity [phosphorylase] phosphatase activity Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate. EC:3.1.3.17|MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN go-plus.json glycogen phosphorylase phosphatase activity|phosphorylase phosphatase activity|phosphorylase a phosphohydrolase activity|phosphorylase a phosphatase activity|type 1 protein phosphatase activity|protein phosphatase C|PR-enzyme http://purl.obolibrary.org/obo/GO_0050196 GO:0050197 biolink:MolecularActivity phytanate-CoA ligase activity Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA. MetaCyc:PHYTANATE--COA-LIGASE-RXN|EC:6.2.1.24|Reactome:R-HSA-389622|KEGG_REACTION:R03631|RHEA:21380 go-plus.json phytanate:CoA ligase (AMP-forming)|phytanoyl-CoA ligase activity http://purl.obolibrary.org/obo/GO_0050197 NCBITaxon:5888 biolink:OrganismalEntity Paramecium tetraurelia go-plus.json Paramecium aurelia syngen 4 http://purl.obolibrary.org/obo/NCBITaxon_5888 NCBITaxon:5884 biolink:OrganismalEntity Paramecium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_5884 UBERON:0009570 biolink:AnatomicalEntity spinal cord sulcus limitans A sulcus limitans of neural tube that is part of a future spinal cord. go-plus.json spinal cord lateral wall sulcus limitans http://purl.obolibrary.org/obo/UBERON_0009570 CHEBI:17769 biolink:ChemicalSubstance 4-aminobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_17769 CHEBI:17767 biolink:ChemicalSubstance D-mannonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17767 chebi_ph7_3 CHEBI:17768 biolink:ChemicalSubstance N-acetylputrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17768 CHEBI:17766 biolink:ChemicalSubstance cyclohexane-1,3-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_17766 chebi_ph7_3 CHEBI:17763 biolink:ChemicalSubstance 4-methylumbelliferyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17763 chebi_ph7_3 UBERON:0009571 biolink:AnatomicalEntity ventral midline In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009571 UBERON:0009572 biolink:AnatomicalEntity lumen of central canal of spinal cord A cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is contiguous with the ventricular system of the brain. The central canal represents the adult remainder of the neural tube. go-plus.json spinal cord lumen|central canal lumen|cavity of central canal of spinal cord|neural lumen http://purl.obolibrary.org/obo/UBERON_0009572 CHEBI:17764 biolink:ChemicalSubstance 2-C-methyl-D-erythritol 4-(dihydrogen phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_17764 CHEBI:17761 biolink:ChemicalSubstance ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17761 chebi_ph7_3 CHEBI:17762 biolink:ChemicalSubstance 5alpha-cholestan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_17762 chebi_ph7_3 UBERON:0009576 biolink:AnatomicalEntity medulla oblongata sulcus limitans A sulcus limitans of neural tube that is part of a future medulla oblongata. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009576 CHEBI:17760 biolink:ChemicalSubstance methyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17760 UBERON:0009577 biolink:AnatomicalEntity metencephalon sulcus limitans A sulcus limitans of neural tube that is part of a future metencephalon. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009577 UBERON:0009578 biolink:AnatomicalEntity myelencephalon sulcus limitans A sulcus limitans of neural tube that is part of a future myelencephalon. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009578 UBERON:0009568 biolink:AnatomicalEntity trunk region of vertebral column Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae. In organisms that have a thoracic and lumbar distinction, this corresponds to the sum of both of these regions. go-plus.json trunk skeleton|trunk vertebral column|trunk spine|thoracolumbar column|thoracolumbar vertebrae set|thoracolumbar region|presacral region|thoracolumbar vertebral column|thoracolumbar region of vertebral column|trunk region|trunk vertebrae series http://purl.obolibrary.org/obo/UBERON_0009568 UBERON:0010546 biolink:AnatomicalEntity metapodial skeleton Subdivision of skeleton that corresponds to metapodium region, between acropodial skeleton and mesopdoial skeleton. go-plus.json metapodium|metapodial skeleton|skeleton of metapodium|metapodium skeleton|metacarpal/metatarsal skeleton|skeletal parts of metapodium http://purl.obolibrary.org/obo/UBERON_0010546 UBERON:0009569 biolink:AnatomicalEntity subdivision of trunk go-plus.json trunk subdivision|region of trunk http://purl.obolibrary.org/obo/UBERON_0009569 UBERON:0010544 biolink:AnatomicalEntity metacarpus skeleton The metacarpus is the intermediate part of the manus skeleton that is located between the phalanges (bones of the fingers) distally and the carpus which forms the connection to the forearm. The metacarpus consists of metacarpal bones. The metacarpals form a transverse arch to which the rigid row of distal carpal bones are fixed. The peripheral metacarpals (those of the thumb and little finger) form the sides of the cup of the palmar gutter and as they are brought together they deepen this concavity. The index metacarpal is the most firmly fixed, while the thumb metacarpal articulates with the trapezium and acts independently from the others. The middle metacarpals are tightly united to the carpus by intrinsic interlocking bone elements at their bases. The ring metacarpal forms a transitional element of the semi-independent last metacarpal. [WP,unvetted]. go-plus.json ossa metacarpi [I-V]|fore metapodium|metacarpalia|set of metacarpals|metacarpal bones|ossa metacarpalia [I-V]|skeleton of metacarpus|anterior metapodial skeleton|fore metapodial skeleton|metacarpals [I-V]|metacarpals set|set of metacarpal bones|anterior metapodium|set of metacarpals [I-V]|metacarpal skeleton http://purl.obolibrary.org/obo/UBERON_0010544 UBERON:0010545 biolink:AnatomicalEntity metatarsus skeleton Limb segment that consists of the long bones of the pes. The metatarsals are analogous to the metacarpal bones of the manus. go-plus.json ossa metatarsalia|ossa metatarsi[I-V]|posterior metapodium|metatarsals [I-V]|posterior metapodial skeleton|set of metatarsal bones|metatarsalia|set of metatarsals [I-V]|metatarsal bones set|metatarsal skeleton|ossa metatarsalia [I-V]|skeleton of metatarsus http://purl.obolibrary.org/obo/UBERON_0010545 CHEBI:17759 biolink:ChemicalSubstance cholesta-5,7-dien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17759 chebi_ph7_3 CHEBI:17756 biolink:ChemicalSubstance (S)-mandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17756 chebi_ph7_3 CHEBI:17757 biolink:ChemicalSubstance plastoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_17757 chebi_ph7_3 CHEBI:17754 biolink:ChemicalSubstance glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17754 chebi_ph7_3 CHEBI:17755 biolink:ChemicalSubstance cystathionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17755 CHEBI:17752 biolink:ChemicalSubstance N(6)-acetyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17752 CHEBI:17750 biolink:ChemicalSubstance glycine betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17750 chebi_ph7_3 CHEBI:17751 biolink:ChemicalSubstance dihydrostreptomycin 3'alpha,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_17751 UBERON:0009564 biolink:AnatomicalEntity distal limb integumentary appendage A nail, hoof or claw. go-plus.json keratin sheath|unguis|keratin plate|hoof, claw or nail|hoof or claw http://purl.obolibrary.org/obo/UBERON_0009564 UBERON:0009565 biolink:AnatomicalEntity nail of manual digit A nail that is part of a manual digit. go-plus.json finger nail|forelimb digit claw|nail of finger|manual claw|fingernail|claw of hand|nail plate of finger|claw of manus http://purl.obolibrary.org/obo/UBERON_0009565 UBERON:0009566 biolink:AnatomicalEntity intestinal submucosa A submucosa that is part of a intestine. go-plus.json submucosa of intestine http://purl.obolibrary.org/obo/UBERON_0009566 UBERON:0009567 biolink:AnatomicalEntity nail of pedal digit A nail that is part of a pedal digit. go-plus.json nail plate of toe|hindlimb digit claw|toe nail|nail of toe|pedal claw|claw of toe|toenail|nail of pes|claw of pes|claw of foot|hindlimb claw http://purl.obolibrary.org/obo/UBERON_0009567 GO:0001136 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001136 GO:0001137 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001137 GO:0001138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001138 GO:0001139 biolink:MolecularActivity RNA polymerase II complex recruiting activity Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. go-plus.json transcription factor activity, core RNA polymerase II recruiting|core RNA polymerase II recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001139 GO:0001132 biolink:MolecularActivity obsolete RNA polymerase II transcription factor activity, TBP-class protein binding OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. go-plus.json TRF protein binding RNA polymerase II transcription factor activity|TBP-class protein binding RNA polymerase II transcription factor activity|TATA-binding protein binding RNA polymerase II transcription factor activity http://purl.obolibrary.org/obo/GO_0001132 GO:0001133 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001133 GO:0001134 biolink:MolecularActivity obsolete transcription regulator recruiting activity OBSOLETE. The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation. go-plus.json transcription factor recruiting activity|transcription factor activity, transcription factor recruiting|transcription factor recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001134 GO:0001135 biolink:MolecularActivity obsolete RNA polymerase II transcription regulator recruiting activity OBSOLETE. The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation. go-plus.json RNA polymerase II transcription factor recruiting activity|transcription factor activity, TFIIH-class transcription factor recruiting|transcription factor activity, TFIIF-class transcription factor recruiting|transcription factor activity, TFIIE-class transcription factor recruiting|TFIIH-class transcription factor recruiting transcription factor activity|TFIIF-class transcription factor recruiting transcription factor activity|transcription factor activity, RNA polymerase II transcription factor recruiting|TFIIE-class transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001135 GO:0001130 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001130 GO:0001131 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001131 GO:0015777 biolink:BiologicalProcess teichoic acid transport The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues. go-plus.json http://purl.obolibrary.org/obo/GO_0015777 CHEBI:27081 biolink:ChemicalSubstance transition element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_27081 CHEBI:27082 biolink:ChemicalSubstance trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_27082 chebi_ph7_3 GO:0015778 biolink:BiologicalProcess hexuronide transport The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate. go-plus.json http://purl.obolibrary.org/obo/GO_0015778 GO:0015779 biolink:BiologicalProcess glucuronoside transport The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate. go-plus.json glucuronide transport http://purl.obolibrary.org/obo/GO_0015779 CHEBI:27083 biolink:ChemicalSubstance trehalose mycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27083 CHEBI:27084 biolink:ChemicalSubstance trehalose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27084 GO:0015773 biolink:BiologicalProcess raffinose transport The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol. go-plus.json http://purl.obolibrary.org/obo/GO_0015773 GO:0015774 biolink:BiologicalProcess polysaccharide transport The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json http://purl.obolibrary.org/obo/GO_0015774 GO:0015775 biolink:BiologicalProcess beta-glucan transport The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0015775 GO:0015776 biolink:BiologicalProcess capsular polysaccharide transport The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi. go-plus.json capsular-polysaccharide transport|capsule polysaccharide transport http://purl.obolibrary.org/obo/GO_0015776 CHEBI:76001 biolink:ChemicalSubstance (R)-laudanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_76001 chebi_ph7_3 CHEBI:52035 biolink:ChemicalSubstance sulfooxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52035 GO:0015770 biolink:BiologicalProcess sucrose transport The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside. go-plus.json http://purl.obolibrary.org/obo/GO_0015770 GO:0015771 biolink:BiologicalProcess trehalose transport The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0015771 GO:0015772 biolink:BiologicalProcess oligosaccharide transport The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0015772 CHEBI:52030 biolink:ChemicalSubstance murideoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52030 CHEBI:52031 biolink:ChemicalSubstance glycochenodeoxycholic acid 7-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52031 GO:0001147 biolink:MolecularActivity transcription termination site sequence-specific DNA binding Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon. go-plus.json bacterial-type RNA polymerase termination site sequence-specific DNA binding|mitochondrial RNA polymerase termination site sequence-specific DNA binding|transcription termination site DNA binding|mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity|transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding http://purl.obolibrary.org/obo/GO_0001147 GO:0001148 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001148 GO:0001149 biolink:MolecularActivity obsolete transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding OBSOLETE. Binding to a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase. go-plus.json bacterial-type RNA polymerase termination site sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001149 GO:0001143 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001143 GO:0001144 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001144 CHEBI:52028 biolink:ChemicalSubstance 8-methoxyfurocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52028 chebi_ph7_3 GO:0001145 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001145 GO:0001146 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001146 GO:0001140 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001140 GO:0001141 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001141 GO:0001142 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001142 CHEBI:27086 biolink:ChemicalSubstance tributylstannane go-plus.json http://purl.obolibrary.org/obo/CHEBI_27086 CHEBI:27092 biolink:ChemicalSubstance tricarboxylic acid trianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_27092 GO:0015788 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015788 GO:0015789 biolink:BiologicalProcess UDP-N-acetylgalactosamine transmembrane transport The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. go-plus.json UDP-N-acetylgalactosamine transport http://purl.obolibrary.org/obo/GO_0015789 CHEBI:27093 biolink:ChemicalSubstance tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_27093 GO:0015784 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015784 GO:0015785 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015785 GO:0015786 biolink:BiologicalProcess UDP-glucose transmembrane transport The process in which UDP-glucose is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0015786 GO:0015787 biolink:BiologicalProcess UDP-glucuronic acid transmembrane transport The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. go-plus.json UDP-glucuronic acid transport http://purl.obolibrary.org/obo/GO_0015787 GO:0015780 biolink:BiologicalProcess nucleotide-sugar transmembrane transport The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json nucleotide-sugar transport http://purl.obolibrary.org/obo/GO_0015780 CHEBI:52023 biolink:ChemicalSubstance hyodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52023 GO:0015781 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015781 GO:0015782 biolink:BiologicalProcess CMP-N-acetylneuraminate transmembrane transport The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json CMP-N-acetylneuraminate transport|CMP-sialic acid transport http://purl.obolibrary.org/obo/GO_0015782 CHEBI:52025 biolink:ChemicalSubstance 8-hydroxyfurocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52025 chebi_ph7_3 GO:0015783 biolink:BiologicalProcess GDP-fucose transmembrane transport The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-fucose transport http://purl.obolibrary.org/obo/GO_0015783 CHEBI:52026 biolink:ChemicalSubstance amorpha-4,11-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_52026 chebi_ph7_3 CHEBI:52020 biolink:ChemicalSubstance 6-decylubiquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_52020 chebi_ph7_3 CHEBI:52021 biolink:ChemicalSubstance 6-decylubiquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52021 chebi_ph7_3 CHEBI:52022 biolink:ChemicalSubstance taurohyocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52022 GO:0001114 biolink:CellularComponent protein-DNA-RNA complex A macromolecular complex containing protein, DNA, and RNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0001114 GO:0001115 biolink:BiologicalProcess protein-DNA-RNA complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex. go-plus.json protein-DNA-RNA complex subunit organisation http://purl.obolibrary.org/obo/GO_0001115 GO:0001116 biolink:BiologicalProcess protein-DNA-RNA complex assembly The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex. go-plus.json http://purl.obolibrary.org/obo/GO_0001116 GO:0001117 biolink:BiologicalProcess protein-DNA-RNA complex disassembly The disaggregation of a protein-DNA-RNA complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0001117 GO:0001110 biolink:BiologicalProcess promoter clearance from RNA polymerase III promoter Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase. go-plus.json http://purl.obolibrary.org/obo/GO_0001110 GO:0001111 biolink:BiologicalProcess promoter clearance from RNA polymerase II promoter Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. go-plus.json promoter escape from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0001111 GO:0001112 biolink:BiologicalProcess DNA-templated transcription open complex formation Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. go-plus.json promoter melting|DNA-templated transcriptional open complex formation|DNA-dependent transcriptional open complex formation http://purl.obolibrary.org/obo/GO_0001112 GO:0001113 biolink:BiologicalProcess transcription open complex formation at RNA polymerase II promoter Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. go-plus.json transcriptional open complex formation at RNA polymerase II promoter|RNA polymerase II promoter melting http://purl.obolibrary.org/obo/GO_0001113 CHEBI:134408 biolink:ChemicalSubstance N-acetylcadaverine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134408 chebi_ph7_3 CHEBI:134409 biolink:ChemicalSubstance N(alpha)-acetyl-L-methionyl-L-asparagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134409 CHEBI:134406 biolink:ChemicalSubstance prostaglandin G3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134406 CHEBI:134407 biolink:ChemicalSubstance prostaglandin H3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134407 GO:0015759 biolink:BiologicalProcess beta-glucoside transport The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration. go-plus.json http://purl.obolibrary.org/obo/GO_0015759 GO:0039722 biolink:BiologicalProcess suppression by virus of host toll-like receptor signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism. go-plus.json suppression by virus of host TLR signaling pathway|inhibition of host TLR pathway by virus http://purl.obolibrary.org/obo/GO_0039722 GO:0015755 biolink:BiologicalProcess fructose transmembrane transport The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. go-plus.json fructose transport http://purl.obolibrary.org/obo/GO_0015755 CHEBI:134400 biolink:ChemicalSubstance cationic peptidyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_134400 GO:0039723 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1. go-plus.json inhibition of host TBK1 by virus|suppression by virus of host TBK1 activity http://purl.obolibrary.org/obo/GO_0039723 GO:0015756 biolink:BiologicalProcess fucose transmembrane transport The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose. go-plus.json fucose transport http://purl.obolibrary.org/obo/GO_0015756 GO:0039720 biolink:CellularComponent virogenic stroma A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled. go-plus.json VS http://purl.obolibrary.org/obo/GO_0039720 GO:0015757 biolink:BiologicalProcess galactose transmembrane transport The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. go-plus.json galactose transport http://purl.obolibrary.org/obo/GO_0015757 GO:0039721 biolink:CellularComponent peristromal region viral factory A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses. go-plus.json PR http://purl.obolibrary.org/obo/GO_0039721 GO:0015758 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015758 GO:0015751 biolink:BiologicalProcess arabinose transmembrane transport The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json arabinose transport http://purl.obolibrary.org/obo/GO_0015751 GO:0015752 biolink:BiologicalProcess D-ribose transmembrane transport The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. go-plus.json D-ribose transport http://purl.obolibrary.org/obo/GO_0015752 CHEBI:134405 biolink:ChemicalSubstance S-anthraniloyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134405 GO:0039724 biolink:BiologicalProcess suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E). go-plus.json inhibition of host IKBKE by virus|suppression by virus of host IKBKE activity http://purl.obolibrary.org/obo/GO_0039724 GO:0015753 biolink:BiologicalProcess D-xylose transmembrane transport The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides. go-plus.json D-xylose transport http://purl.obolibrary.org/obo/GO_0015753 GO:0015754 biolink:BiologicalProcess allose transmembrane transport The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. go-plus.json allose transport http://purl.obolibrary.org/obo/GO_0015754 CHEBI:76024 biolink:ChemicalSubstance dotriacontanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76024 chebi_ph7_3 GO:0015750 biolink:BiologicalProcess pentose transmembrane transport The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule. go-plus.json pentose transport http://purl.obolibrary.org/obo/GO_0015750 GO:0001118 biolink:BiologicalProcess transcription ternary complex disassembly The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components. go-plus.json transcription protein-DNA-RNA complex disassembly http://purl.obolibrary.org/obo/GO_0001118 GO:0001119 biolink:BiologicalProcess protein-DNA-RNA complex remodeling The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex. go-plus.json http://purl.obolibrary.org/obo/GO_0001119 GO:0001125 biolink:BiologicalProcess transcription termination from bacterial-type RNA polymerase promoter The process in which the synthesis of an RNA molecule by a bacterial-type RNA polymerase using a DNA template is completed. go-plus.json http://purl.obolibrary.org/obo/GO_0001125 GO:0001126 biolink:BiologicalProcess bacterial-type RNA polymerase preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on a bacterial-type RNA polymerase promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription. go-plus.json bacterial-type RNA polymerase transcription PIC biosynthesis|bacterial-type RNA polymerase transcription PIC formation|bacterial-type RNA polymerase transcriptional preinitiation complex formation http://purl.obolibrary.org/obo/GO_0001126 GO:0001127 biolink:BiologicalProcess transcription open complex formation at bacterial-type RNA polymerase promoter Any process involved in the melting of the DNA hybrid of the core promoter region within a bacterial-type RNA polymerase promoter to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. go-plus.json transcriptional open complex formation at bacterial-type RNA polymerase promoter http://purl.obolibrary.org/obo/GO_0001127 GO:0001128 biolink:MolecularActivity obsolete RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly OBSOLETE. Binding to an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery. go-plus.json RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly http://purl.obolibrary.org/obo/GO_0001128 GO:0001121 biolink:BiologicalProcess bacterial transcription The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter. go-plus.json transcription from bacterial-type RNA polymerase promoter http://purl.obolibrary.org/obo/GO_0001121 GO:0001122 biolink:BiologicalProcess promoter clearance from bacterial-type RNA polymerase promoter Any process involved in the transition from the initiation to the elongation phase of transcription by a bacterial-type RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance generally involves dissociation of the sigma initiation factor. go-plus.json http://purl.obolibrary.org/obo/GO_0001122 GO:0001123 biolink:BiologicalProcess transcription initiation from bacterial-type RNA polymerase promoter Any process involved in the assembly of bacterial-type RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0001123 GO:0001124 biolink:BiologicalProcess transcription elongation from bacterial-type RNA polymerase promoter The extension of an RNA molecule after transcription initiation and promoter clearance at a bacterial-type RNA polymerase promoter by the addition of ribonucleotides catalyzed by a bacterial-type RNA polymerase. go-plus.json RNA elongation from bacterial-type RNA polymerase promoter http://purl.obolibrary.org/obo/GO_0001124 GO:0039719 biolink:CellularComponent tube viral factory A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories. go-plus.json http://purl.obolibrary.org/obo/GO_0039719 CHEBI:134417 biolink:ChemicalSubstance 10,11-dihydro-12-oxoleukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134417 GO:0039717 biolink:CellularComponent spherule viral factory A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus. Wikipedia:Viroplasm go-plus.json http://purl.obolibrary.org/obo/GO_0039717 GO:0039718 biolink:CellularComponent double membrane vesicle viral factory A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae. go-plus.json DMV viral factory http://purl.obolibrary.org/obo/GO_0039718 GO:0001120 biolink:BiologicalProcess protein-DNA complex remodeling The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex. go-plus.json http://purl.obolibrary.org/obo/GO_0001120 CL:0010021 biolink:Cell cardiac myoblast go-plus.json http://purl.obolibrary.org/obo/CL_0010021 CL:0010022 biolink:Cell cardiac neuron go-plus.json http://purl.obolibrary.org/obo/CL_0010022 CHEBI:27066 biolink:ChemicalSubstance (9R,10R)-9,10-dihydrophenanthrene-9,10-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27066 chebi_ph7_3 CL:0010020 biolink:Cell cardiac glial cell go-plus.json http://purl.obolibrary.org/obo/CL_0010020 GO:0015766 biolink:BiologicalProcess disaccharide transport The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units. go-plus.json http://purl.obolibrary.org/obo/GO_0015766 GO:0039711 biolink:BiologicalProcess cytoplasmic helical capsid assembly The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome. go-plus.json http://purl.obolibrary.org/obo/GO_0039711 GO:0015767 biolink:BiologicalProcess lactose transport The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0015767 GO:0039712 biolink:BiologicalProcess obsolete induction by virus of host catalytic activity OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host catalytic activity. go-plus.json induction by virus of host enzyme activity http://purl.obolibrary.org/obo/GO_0039712 CHEBI:134412 biolink:ChemicalSubstance 10-formyltetrahydrofolyl-(Glu)n go-plus.json http://purl.obolibrary.org/obo/CHEBI_134412 GO:0015768 biolink:BiologicalProcess maltose transport The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch. go-plus.json http://purl.obolibrary.org/obo/GO_0015768 GO:0015769 biolink:BiologicalProcess melibiose transport The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0015769 GO:0039710 biolink:BiologicalProcess cytoplasmic icosahedral capsid assembly The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome. go-plus.json http://purl.obolibrary.org/obo/GO_0039710 GO:0039715 biolink:CellularComponent nuclear viral factory A viral factory located in the nucleus of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0039715 GO:0015762 biolink:BiologicalProcess rhamnose transmembrane transport The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids. go-plus.json rhamnose transport http://purl.obolibrary.org/obo/GO_0015762 GO:0039716 biolink:CellularComponent viroplasm viral factory A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae. Wikipedia:Viroplasm go-plus.json http://purl.obolibrary.org/obo/GO_0039716 CHEBI:134416 biolink:ChemicalSubstance 3-oxo fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_134416 GO:0015763 biolink:BiologicalProcess N-acetylgalactosamine transport The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine. go-plus.json http://purl.obolibrary.org/obo/GO_0015763 CHEBI:134413 biolink:ChemicalSubstance 10-formyltetrahydrofolyl-(Glu)n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134413 chebi_ph7_3 GO:0039713 biolink:CellularComponent viral factory An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments. VZ:1951 go-plus.json virus factory http://purl.obolibrary.org/obo/GO_0039713 GO:0015764 biolink:BiologicalProcess N-acetylglucosamine transport The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015764 GO:0015765 biolink:BiologicalProcess methylgalactoside transport The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0015765 CHEBI:134414 biolink:ChemicalSubstance 2-hydroxyhexacosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_134414 chebi_ph7_3 GO:0039714 biolink:CellularComponent cytoplasmic viral factory A viral factory located in the cytoplasm of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0039714 CHEBI:76032 biolink:ChemicalSubstance 7(1)-hydroxychlorophyll a go-plus.json http://purl.obolibrary.org/obo/CHEBI_76032 GO:0015760 biolink:BiologicalProcess glucose-6-phosphate transport The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6. go-plus.json http://purl.obolibrary.org/obo/GO_0015760 GO:0015761 biolink:BiologicalProcess mannose transmembrane transport The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. go-plus.json mannose transport http://purl.obolibrary.org/obo/GO_0015761 GO:0001129 biolink:MolecularActivity obsolete RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. go-plus.json TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|TATA-binding protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly http://purl.obolibrary.org/obo/GO_0001129 CHEBI:76036 biolink:ChemicalSubstance (R)-2-hydroxylignoceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_76036 GO:0050103 biolink:MolecularActivity dextrin dextranase activity Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1). MetaCyc:DEXTRIN-DEXTRANASE-RXN|RHEA:14625|EC:2.4.1.2 go-plus.json dextran dextrinase activity|dextrin 6-glucosyltransferase activity|1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050103 GO:1990277 biolink:BiologicalProcess parasexual conjugation with cellular fusion A conjugation process that results in the union of cellular and genetic information from compatible mating types, without the formation of zygotes. An example of this process is found in Candida albicans. go-plus.json mating http://purl.obolibrary.org/obo/GO_1990277 GO:0050104 biolink:MolecularActivity L-gulonate 3-dehydrogenase activity Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH. EC:1.1.1.45|RHEA:12889|MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN|Reactome:R-HSA-5661290|KEGG_REACTION:R02640 go-plus.json L-3-aldonate dehydrogenase activity|L-beta-hydroxy-acid-NAD-oxidoreductase activity|L-3-aldonic dehydrogenase activity|L-gulonate:NAD+ 3-oxidoreductase activity|L-gulonic acid dehydrogenase activity|L-beta-hydroxyacid dehydrogenase activity|L-3-hydroxyacid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050104 GO:1990278 biolink:BiologicalProcess obsolete positive regulation of MBF transcription factor activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor MBF. go-plus.json positive regulation of MBF transcription factor activity http://purl.obolibrary.org/obo/GO_1990278 GO:1990279 biolink:BiologicalProcess obsolete negative regulation of MBF transcription factor activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor MBF. go-plus.json negative regulation of MBF transcription factor activity http://purl.obolibrary.org/obo/GO_1990279 GO:0050101 biolink:MolecularActivity mimosinase activity Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine. EC:3.5.1.61|MetaCyc:MIMOSINASE-RXN|RHEA:13373|KEGG_REACTION:R04350 go-plus.json mimosine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050101 GO:0050102 biolink:MolecularActivity cellodextrin phosphorylase activity Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN|EC:2.4.1.49|RHEA:23024 go-plus.json beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity|1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050102 GO:1990273 biolink:BiologicalProcess snRNA 5'-end processing Any process involved in forming the mature 5' end of an snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990273 GO:0050107 biolink:MolecularActivity monoterpenol O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester. MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.69 go-plus.json acetyl-CoA:monoterpenol O-acetyltransferase activity|menthol transacetylase activity http://purl.obolibrary.org/obo/GO_0050107 GO:1990274 biolink:BiologicalProcess mitotic actomyosin contractile ring disassembly Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle. go-plus.json mitotic actomyosin ring disassembly|mitotic cytokinetic ring disassembly|mitotic CAR disassembly|mitotic contractile actomyosin ring disassembly|mitotic constriction ring disassembly http://purl.obolibrary.org/obo/GO_1990274 GO:0050108 biolink:MolecularActivity monoterpenyl-diphosphatase activity Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate. MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN|EC:3.1.7.3 go-plus.json monoterpenyl-diphosphate diphosphohydrolase activity|bornyl pyrophosphate hydrolase activity|monoterpenyl-pyrophosphatase activity|bornyl diphosphate hydrolase activity http://purl.obolibrary.org/obo/GO_0050108 GO:0050105 biolink:MolecularActivity L-gulonolactone oxidase activity Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2. MetaCyc:L-GULONOLACTONE-OXIDASE-RXN|RHEA:32363|EC:1.1.3.8 go-plus.json L-gulono-gamma-lactone:O2 oxidoreductase activity|L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity|GLO activity|L-gulono-gamma-lactone:oxidoreductase activity|L-gulono-gamma-lactone oxidase activity http://purl.obolibrary.org/obo/GO_0050105 GO:1990275 biolink:MolecularActivity preribosome binding Binding to a preribosome. go-plus.json http://purl.obolibrary.org/obo/GO_1990275 GO:1990276 biolink:MolecularActivity RNA 5'-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990276 GO:0050106 biolink:MolecularActivity monomethyl-sulfatase activity Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate. EC:3.1.6.16|KEGG_REACTION:R01145|MetaCyc:MONOMETHYL-SULFATASE-RXN|RHEA:14221 go-plus.json monomethyl-sulfate sulfohydrolase activity|monomethyl-sulphatase activity http://purl.obolibrary.org/obo/GO_0050106 GO:0039708 biolink:BiologicalProcess nuclear capsid assembly The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly. VZ:1516 go-plus.json http://purl.obolibrary.org/obo/GO_0039708 GO:0039709 biolink:BiologicalProcess cytoplasmic capsid assembly The assembly of a virus capsid that occurs in the cytoplasm. VZ:1950 go-plus.json http://purl.obolibrary.org/obo/GO_0039709 GO:1990270 biolink:CellularComponent platelet-derived growth factor receptor-ligand complex A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes. go-plus.json PDGF-CC-receptor alpha-beta complex|PDGF-DD-receptor alpha-beta complex|PDGF-BB-receptor alpha-beta complex|receptor-ligand complex|PDGF-AA-receptor alpha complex|PDGF-CC-receptor alpha complex|PDGF-BB-receptor alpha complex|PDGF receptor-ligand complex|PDGF-AB-receptor alpha complex|PDGF complex|PDGF-AB-receptor beta complex|PDGF-DD-receptor beta complex|PDGF-CC-receptor beta complex|PDGF-BB-receptor beta complex http://purl.obolibrary.org/obo/GO_1990270 GO:0050109 biolink:MolecularActivity morphine 6-dehydrogenase activity Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+. MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN|EC:1.1.1.218 go-plus.json morphine:NAD(P)+ 6-oxidoreductase activity|reductase, naloxone|naloxone reductase activity http://purl.obolibrary.org/obo/GO_0050109 GO:0039706 biolink:MolecularActivity co-receptor binding Binding to a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0039706 GO:1990271 biolink:MolecularActivity obsolete anti-Mullerian hormone OBSOLETE. Combining with anti-Mullerian hormone to initiate a change in cell activity. go-plus.json anti-Mullerian hormone http://purl.obolibrary.org/obo/GO_1990271 CL:0010012 biolink:Cell cerebral cortex neuron A neuron that is part_of a cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/CL_0010012 GO:0039707 biolink:BiologicalProcess pore formation by virus in membrane of host cell The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism. go-plus.json viroporin|pore formation in membrane of host cell by virus http://purl.obolibrary.org/obo/GO_0039707 GO:1990272 biolink:MolecularActivity anti-Mullerian hormone receptor activity Combining with anti-Mullerian hormone to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_1990272 GO:0015737 biolink:BiologicalProcess galacturonate transmembrane transport The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json galacturonate transport http://purl.obolibrary.org/obo/GO_0015737 CL:0010010 biolink:Cell cerebellar stellate cell go-plus.json http://purl.obolibrary.org/obo/CL_0010010 GO:0015738 biolink:BiologicalProcess glucuronate transmembrane transport The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json glucuronate transport http://purl.obolibrary.org/obo/GO_0015738 CL:0010011 biolink:Cell cerebral cortex GABAergic interneuron A GABAergic interneuron whose soma is located in the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/CL_0010011 GO:0015739 biolink:BiologicalProcess sialic acid transport The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015739 GO:0039700 biolink:BiologicalProcess fusion of viral membrane with host outer nuclear membrane Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit. go-plus.json fusion of viral membrane with host outer nuclear membrane involved in nuclear egress|viral primary envelope fusion with host outer nuclear membrane http://purl.obolibrary.org/obo/GO_0039700 GO:0015733 biolink:BiologicalProcess shikimate transmembrane transport The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json shikimate transport http://purl.obolibrary.org/obo/GO_0015733 CL:0000680 biolink:Cell muscle precursor cell A non-terminally differentiated cell that is capable of developing into a muscle cell. go-plus.json http://purl.obolibrary.org/obo/CL_0000680 GO:0039701 biolink:BiologicalProcess microtubule-dependent intracellular transport of viral material towards cell periphery The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane. VZ:1816 go-plus.json http://purl.obolibrary.org/obo/GO_0039701 CL:0000681 biolink:Cell radial glial cell A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. go-plus.json forebrain radial glial cell http://purl.obolibrary.org/obo/CL_0000681 GO:0015734 biolink:BiologicalProcess taurine transport The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015734 GO:0015735 biolink:BiologicalProcess uronic acid transmembrane transport The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json uronic acid transport http://purl.obolibrary.org/obo/GO_0015735 CL:0000683 biolink:Cell ependymoglial cell A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. go-plus.json ependymal astrocyte http://purl.obolibrary.org/obo/CL_0000683 GO:0015736 biolink:BiologicalProcess hexuronate transmembrane transport The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6. go-plus.json hexuronate transport http://purl.obolibrary.org/obo/GO_0015736 GO:0039704 biolink:BiologicalProcess viral translational shunt A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site. VZ:608 go-plus.json ribosomal shunt initiation pathway http://purl.obolibrary.org/obo/GO_0039704 UBERON:0009638 biolink:AnatomicalEntity orbitosphenoid ossification center go-plus.json orbitosphenoid center http://purl.obolibrary.org/obo/UBERON_0009638 GO:0039705 biolink:BiologicalProcess viral translational readthrough The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons. VZ:859 go-plus.json viral stop codon readthrough|viral RNA suppression of termination http://purl.obolibrary.org/obo/GO_0039705 CHEBI:76042 biolink:ChemicalSubstance aromatic amino-acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_76042 chebi_ph7_3 GO:0015730 biolink:BiologicalProcess propanoate transport The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json propionate transport http://purl.obolibrary.org/obo/GO_0015730 GO:0039702 biolink:BiologicalProcess viral budding via host ESCRT complex Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process. VZ:1536 go-plus.json host-assisted viral budding|viral budding through the ESCRT machinery http://purl.obolibrary.org/obo/GO_0039702 CL:0000686 biolink:Cell cerebrospinal fluid secreting cell A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. go-plus.json http://purl.obolibrary.org/obo/CL_0000686 CHEBI:42677 biolink:ChemicalSubstance (2R)-2-hydroxypropylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_42677 chebi_ph7_3 GO:0015731 biolink:BiologicalProcess 3-hydroxyphenyl propanoate transport The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json 3-hydroxyphenyl propionate transport http://purl.obolibrary.org/obo/GO_0015731 GO:0015732 biolink:BiologicalProcess prostaglandin transport The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015732 GO:0039703 biolink:BiologicalProcess RNA replication The cellular metabolic process in which a cell duplicates one or more molecules of RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0039703 CL:0010017 biolink:Cell zygote A zygote in a plant or an animal. go-plus.json http://purl.obolibrary.org/obo/CL_0010017 CL:0009014 biolink:Cell Peyer's patch lymphocyte A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells. go-plus.json Peyer's patch resident lymphocyte|small intestine Peyer's patch lymphocyte http://purl.obolibrary.org/obo/CL_0009014 CL:0009015 biolink:Cell Peyer's patch follicular dendritic cell A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside. go-plus.json http://purl.obolibrary.org/obo/CL_0009015 CHEBI:76044 biolink:ChemicalSubstance omega-hydroxytriacontanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76044 chebi_ph7_3 UBERON:0009630 biolink:AnatomicalEntity root of thoracic nerve A spinal nerve root that is part of a thoracic nerve. go-plus.json thoracic neural root|nerve root part of thoracic spinal cord|thoracic nerve root http://purl.obolibrary.org/obo/UBERON_0009630 GO:0050100 biolink:MolecularActivity methylitaconate delta-isomerase activity Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate. MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN|EC:5.3.3.6|RHEA:23480|KEGG_REACTION:R03070 go-plus.json methylitaconate D-isomerase activity|methylitaconate isomerase activity|methylitaconate delta2-delta3-isomerase activity http://purl.obolibrary.org/obo/GO_0050100 UBERON:0009632 biolink:AnatomicalEntity root of cervical nerve go-plus.json cervical neural root|root of cervical spinal nerve|cervical spinal root|nerve root part of cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0009632 GO:0050114 biolink:MolecularActivity myo-inosose-2 dehydratase activity Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O. EC:4.2.1.44|MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN|KEGG_REACTION:R02782|RHEA:14065 go-plus.json 2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)|inosose 2,3-dehydratase activity|ketoinositol dehydratase activity|2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity http://purl.obolibrary.org/obo/GO_0050114 GO:0001103 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001103 GO:1990288 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990288 GO:0050115 biolink:MolecularActivity myosin-light-chain-phosphatase activity Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate. EC:3.1.3.53|Reactome:R-HSA-419232|MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN go-plus.json myosin-light-chain phosphatase activity|[Myosin light-chain]-phosphatase activity|myosin light chain kinase phosphatase activity|protein phosphatase 2A|myosin light-chain kinase phosphatase activity|myosin-light-chain-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050115 GO:0001104 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001104 GO:1990289 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990289 GO:0001105 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001105 GO:0050112 biolink:MolecularActivity inositol 2-dehydrogenase activity Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH. KEGG_REACTION:R01183|EC:1.1.1.18|MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN|RHEA:16949 go-plus.json myo-inositol 2-dehydrogenase activity|inositol:NAD 2-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050112 GO:0050113 biolink:MolecularActivity inositol oxygenase activity Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+). MetaCyc:MYO-INOSITOL-OXYGENASE-RXN|RHEA:23696|KEGG_REACTION:R01184|EC:1.13.99.1|Reactome:R-HSA-5678327 go-plus.json meso-inositol oxygenase activity|myo-inositol oxygenase activity|MOO activity|myo-inositol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050113 GO:0001106 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001106 GO:0050118 biolink:MolecularActivity N-acetyldiaminopimelate deacetylase activity Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate. EC:3.5.1.47|KEGG_REACTION:R02733|MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN|RHEA:20405 go-plus.json 6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-LL-diaminopimelate deacylase activity|N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-L-diaminopimelic acid deacylase activity http://purl.obolibrary.org/obo/GO_0050118 GO:1990284 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990284 GO:0001100 biolink:BiologicalProcess negative regulation of exit from mitosis Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity). go-plus.json down regulation of exit from mitosis|downregulation of exit from mitosis|down-regulation of exit from mitosis|inhibition of exit from mitosis http://purl.obolibrary.org/obo/GO_0001100 GO:0050119 biolink:MolecularActivity N-acetylglucosamine deacetylase activity Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate. EC:3.5.1.33|KEGG_REACTION:R01200|RHEA:20593|Reactome:R-HSA-2022887|MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN go-plus.json N-acetyl-D-glucosaminyl N-deacetylase activity|N-acetyl-D-glucosamine amidohydrolase activity|acetylaminodeoxyglucose acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0050119 GO:1990285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990285 GO:0050116 biolink:MolecularActivity N,N-dimethylformamidase activity Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate. EC:3.5.1.56|RHEA:19517|MetaCyc:NN-DIMETHYLFORMAMIDASE-RXN|KEGG_REACTION:R02509 go-plus.json dimethylformamidase activity|DMFase activity|N,N-dimethylformamide amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050116 GO:0001101 biolink:BiologicalProcess response to acid chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. go-plus.json response to acid anion|response to acid|response to oxoanion http://purl.obolibrary.org/obo/GO_0001101 gocheck_do_not_manually_annotate GO:1990286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990286 GO:0001102 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001102 GO:0050117 biolink:MolecularActivity N-acetyl-beta-alanine deacetylase activity Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate. EC:3.5.1.21|RHEA:23212|MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN|KEGG_REACTION:R00909 go-plus.json N-acetyl-beta-alanine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050117 GO:1990287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990287 CL:0010003 biolink:Cell epithelial cell of alveolus of lung An epithelial cell that is part_of a alveolus of lung. go-plus.json alveolus of lung epithelial cell http://purl.obolibrary.org/obo/CL_0010003 GO:1990280 biolink:BiologicalProcess RNA localization to chromatin A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin. go-plus.json RNA localisation to chromatin http://purl.obolibrary.org/obo/GO_1990280 CL:0010004 biolink:Cell mononuclear cell of bone marrow A mononuclear cell that is part_of a bone marrow. go-plus.json bone marrow mononuclear cell http://purl.obolibrary.org/obo/CL_0010004 GO:1990281 biolink:CellularComponent efflux pump complex A protein complex that is capable of efflux transmembrane transporter activity. go-plus.json efflux transmembrane transporter complex|efflux pump http://purl.obolibrary.org/obo/GO_1990281 CL:0010001 biolink:Cell stromal cell of bone marrow A stromal cell that is part_of a bone marrow. go-plus.json bone marrow stromal cell http://purl.obolibrary.org/obo/CL_0010001 GO:1990282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990282 GO:1990283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990283 CHEBI:42660 biolink:ChemicalSubstance GDP-beta-L-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_42660 GO:0015748 biolink:BiologicalProcess organophosphate ester transport The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0015748 GO:0015749 biolink:BiologicalProcess monosaccharide transmembrane transport The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. go-plus.json monosaccharide transport http://purl.obolibrary.org/obo/GO_0015749 UBERON:0009623 biolink:AnatomicalEntity spinal nerve root The paired bundles of nerve fibers entering and leaving the spinal cord at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots efferent, comprising the axons of spinal motor and autonomic preganglionic neurons. There are, however, some exceptions to this afferent/efferent rule. go-plus.json root of spinal nerve|spinal root|spinal neural root http://purl.obolibrary.org/obo/UBERON_0009623 GO:0015744 biolink:BiologicalProcess succinate transport The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015744 CL:0000691 biolink:Cell stellate interneuron go-plus.json http://purl.obolibrary.org/obo/CL_0000691 GO:0015745 biolink:BiologicalProcess tartrate transmembrane transport The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json tartrate transport http://purl.obolibrary.org/obo/GO_0015745 GO:0015746 biolink:BiologicalProcess citrate transport The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015746 CL:0010009 biolink:Cell camera-type eye photoreceptor cell go-plus.json camera type eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0010009 GO:0015747 biolink:BiologicalProcess urate transport The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json uric acid transport|urate transmembrane transport http://purl.obolibrary.org/obo/GO_0015747 GO:0015740 biolink:BiologicalProcess C4-dicarboxylate transport The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms. go-plus.json http://purl.obolibrary.org/obo/GO_0015740 CL:0000695 biolink:Cell Cajal-Retzius cell One of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. go-plus.json http://purl.obolibrary.org/obo/CL_0000695 CL:0010007 biolink:Cell His-Purkinje system cell go-plus.json http://purl.obolibrary.org/obo/CL_0010007 CL:0000696 biolink:Cell PP cell A cell that stores and secretes pancreatic polypeptide hormone. go-plus.json type F enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000696 GO:0015741 biolink:BiologicalProcess fumarate transport The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015741 CL:0010008 biolink:Cell cardiac endothelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0010008 CHEBI:17699 biolink:ChemicalSubstance 16-hydroxytabersonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17699 GO:0015742 biolink:BiologicalProcess alpha-ketoglutarate transport The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json mitochondrial alpha-ketoglutarate/malate transport|2-oxoglutarate transport http://purl.obolibrary.org/obo/GO_0015742 CL:0010005 biolink:Cell atrioventricular bundle cell A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers. go-plus.json AV bundle cell http://purl.obolibrary.org/obo/CL_0010005 GO:0015743 biolink:BiologicalProcess malate transport The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json mitochondrial alpha-ketoglutarate/malate transport http://purl.obolibrary.org/obo/GO_0015743 CL:0010006 biolink:Cell cardiac blood vessel endothelial cell go-plus.json http://purl.obolibrary.org/obo/CL_0010006 CL:0009025 biolink:Cell mesothelial cell of large intestine A mesothelial cell that is part of the large intestine. go-plus.json http://purl.obolibrary.org/obo/CL_0009025 CHEBI:17697 biolink:ChemicalSubstance N-acetylserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_17697 chebi_ph7_3 CHEBI:76056 biolink:ChemicalSubstance dTDP-beta-L-4-epi-vancosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76056 CHEBI:17698 biolink:ChemicalSubstance chloramphenicol go-plus.json http://purl.obolibrary.org/obo/CHEBI_17698 chebi_ph7_3 CHEBI:76054 biolink:ChemicalSubstance 1-O-oleoyl-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76054 chebi_ph7_3 CHEBI:17695 biolink:ChemicalSubstance casbene go-plus.json http://purl.obolibrary.org/obo/CHEBI_17695 chebi_ph7_3 CHEBI:17696 biolink:ChemicalSubstance isocyanuric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17696 chebi_ph7_3 CHEBI:76055 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76055 chebi_ph7_3 GO:0050110 biolink:MolecularActivity mucinaminylserine mucinaminidase activity Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine. MetaCyc:3.2.1.110-RXN|KEGG_REACTION:R04527|EC:3.2.1.97 go-plus.json endo-beta-N-acetylgalactosaminidase|endo-beta-N-acetyl-D-galactosaminidase activity|D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity http://purl.obolibrary.org/obo/GO_0050110 GO:0001107 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001107 CHEBI:17693 biolink:ChemicalSubstance 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17693 GO:0050111 biolink:MolecularActivity mycocerosate synthase activity Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+). RHEA:10588|KEGG_REACTION:R05189|EC:2.3.1.111|MetaCyc:MYCOCEROSATE-SYNTHASE-RXN go-plus.json mycocerosic acid synthase activity|acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) http://purl.obolibrary.org/obo/GO_0050111 GO:0001108 biolink:MolecularActivity bacterial-type RNA polymerase holo enzyme binding Binding to a component of the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase. go-plus.json basal bacterial-type RNA polymerase transcription machinery binding http://purl.obolibrary.org/obo/GO_0001108 CHEBI:17694 biolink:ChemicalSubstance dihydrolipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_17694 chebi_ph7_3 GO:0001109 biolink:BiologicalProcess promoter clearance during DNA-templated transcription Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. go-plus.json promoter escape|promoter clearance during DNA-dependent transcription http://purl.obolibrary.org/obo/GO_0001109 CHEBI:76058 biolink:ChemicalSubstance chloroorienticin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_76058 CHEBI:17691 biolink:ChemicalSubstance N-feruloylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_17691 UBERON:0009621 biolink:AnatomicalEntity tail somite A somite that is part of a tail. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009621 CHEBI:17692 biolink:ChemicalSubstance cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_17692 CL:0009024 biolink:Cell mesothelial cell of small intestine A mesothelial cell that is part of the small intestine. go-plus.json http://purl.obolibrary.org/obo/CL_0009024 UBERON:0009622 biolink:AnatomicalEntity pronephric proximal straight tubule A proximal straight tubule that is part of a pronephros. go-plus.json proximal straight tubules http://purl.obolibrary.org/obo/UBERON_0009622 GO:1990299 biolink:BiologicalProcess Bub1-Bub3 complex localization to kinetochore A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. go-plus.json http://purl.obolibrary.org/obo/GO_1990299 GO:0050125 biolink:MolecularActivity N-benzyloxycarbonylglycine hydrolase activity Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine. MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN|RHEA:20900|EC:3.5.1.58|KEGG_REACTION:R02551 go-plus.json nalpha-carbobenzoxyamino acid amidohydrolase activity|benzyloxycarbonylglycine hydrolase activity|N-benzyloxycarbonylglycine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase I|nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity http://purl.obolibrary.org/obo/GO_0050125 GO:0050126 biolink:MolecularActivity N-carbamoylputrescine amidase activity Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine. EC:3.5.1.53|KEGG_REACTION:R01152|RHEA:22284|MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN go-plus.json NCP|N-carbamoylputrescine amidohydrolase activity|carbamoylputrescine hydrolase activity http://purl.obolibrary.org/obo/GO_0050126 GO:0050123 biolink:MolecularActivity N-acylmannosamine 1-dehydrogenase activity Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH. MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN|KEGG_REACTION:R02651|RHEA:11540|EC:1.1.1.233 go-plus.json N-acyl-D-mannosamine dehydrogenase activity|N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity|N-acylmannosamine dehydrogenase activity|N-acetyl-D-mannosamine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0050123 GO:0050124 biolink:MolecularActivity N-acylneuraminate-9-phosphatase activity Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate. Reactome:R-HSA-4084989|EC:3.1.3.29|MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN|RHEA:13057 go-plus.json acylneuraminate 9-phosphatase activity|N-acylneuraminic acid 9-phosphate phosphatase activity|N-acylneuraminic (sialic) acid 9-phosphatase activity|N-acylneuraminate-9-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0050124 GO:1990295 biolink:CellularComponent post-anaphase microtubule array A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center. go-plus.json PAA|post-anaphase array http://purl.obolibrary.org/obo/GO_1990295 GO:0050129 biolink:MolecularActivity N-formylglutamate deformylase activity Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate. KEGG_REACTION:R00525|EC:3.5.1.68|RHEA:12476|MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN go-plus.json beta-citryl-L-glutamate-hydrolyzing enzyme|beta-citryl-L-glutamate amidase activity|beta-citrylglutamate amidase activity|beta-citryl-L-glutamate hydrolase activity|N-formylglutamate hydrolase activity|N-formyl-L-glutamate amidohydrolase activity|formylglutamate deformylase activity|beta-citryl-L-glutamate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0050129 GO:1990296 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990296 GO:1990297 biolink:BiologicalProcess renal amino acid absorption A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. go-plus.json http://purl.obolibrary.org/obo/GO_1990297 GO:0050127 biolink:MolecularActivity N-carbamoylsarcosine amidase activity Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine. EC:3.5.1.59|RHEA:20057|KEGG_REACTION:R01563|MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN go-plus.json N-carbamoylsarcosine amidohydrolase activity|CSHase activity|carbamoylsarcosine amidase activity http://purl.obolibrary.org/obo/GO_0050127 GO:0050128 biolink:MolecularActivity N-feruloylglycine deacylase activity Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine. MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN|KEGG_REACTION:R03579|RHEA:10484|EC:3.5.1.71 go-plus.json N-feruloylglycine amidohydrolase activity|N-feruloylglycine hydrolase activity http://purl.obolibrary.org/obo/GO_0050128 GO:1990298 biolink:CellularComponent bub1-bub3 complex Protein complex that associates with the kinetochores. go-plus.json http://purl.obolibrary.org/obo/GO_1990298 GO:0015719 biolink:BiologicalProcess allantoate transport The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json allantoin/allantoate transport http://purl.obolibrary.org/obo/GO_0015719 GO:1990291 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990291 CL:0000666 biolink:Cell fenestrated cell go-plus.json window cell http://purl.obolibrary.org/obo/CL_0000666 GO:1990292 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990292 CL:0000667 biolink:Cell collagen secreting cell An extracellular matrix secreting cell that secretes collagen. go-plus.json http://purl.obolibrary.org/obo/CL_0000667 CHEBI:27013 biolink:ChemicalSubstance tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27013 GO:1990293 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990293 CL:0000669 biolink:Cell pericyte cell An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. go-plus.json pericyte of Rouget|pericyte|ARC|adventitial reticular cell|adventitial cell|cell of Rouget http://purl.obolibrary.org/obo/CL_0000669 GO:1990294 biolink:BiologicalProcess peptidyl-threonine trans-autophosphorylation The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer. go-plus.json http://purl.obolibrary.org/obo/GO_1990294 GO:0015715 biolink:BiologicalProcess nucleotide-sulfate transport The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json nucleotide-sulphate transport http://purl.obolibrary.org/obo/GO_0015715 GO:0015716 biolink:BiologicalProcess organic phosphonate transport The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2). go-plus.json alkylphosphonate transport http://purl.obolibrary.org/obo/GO_0015716 GO:0015717 biolink:BiologicalProcess triose phosphate transport The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json aldotriose phosphate transport http://purl.obolibrary.org/obo/GO_0015717 GO:1990290 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990290 GO:0015718 biolink:BiologicalProcess monocarboxylic acid transport The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015718 GO:0015711 biolink:BiologicalProcess organic anion transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0015711 GO:0015712 biolink:BiologicalProcess hexose phosphate transport The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015712 GO:0015713 biolink:BiologicalProcess phosphoglycerate transmembrane transport The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json phosphoglycerate transport http://purl.obolibrary.org/obo/GO_0015713 UBERON:0009614 biolink:AnatomicalEntity hindbrain neural plate A neural plate that develops_from a presumptive hindbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009614 UBERON:0009615 biolink:AnatomicalEntity midbrain hindbrain boundary neural plate go-plus.json MHB neural plate|midbrain-hindbrain boundary neural plate http://purl.obolibrary.org/obo/UBERON_0009615 CL:0000661 biolink:Cell distal tip cell (sensu Nematoda) go-plus.json http://purl.obolibrary.org/obo/CL_0000661 GO:0015714 biolink:BiologicalProcess phosphoenolpyruvate transport The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015714 UBERON:0009616 biolink:AnatomicalEntity presumptive midbrain A presumptive structure that has the potential to develop into a midbrain. go-plus.json presumptive mesencephalon|early midbrain|future midbrain|mesencephalon http://purl.obolibrary.org/obo/UBERON_0009616 CHEBI:76063 biolink:ChemicalSubstance 1-O-palmityl-2-O-methyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76063 chebi_ph7_3 CHEBI:76064 biolink:ChemicalSubstance 1-palmityl-2-methyl-3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76064 chebi_ph7_3 CL:0000663 biolink:Cell valve cell go-plus.json http://purl.obolibrary.org/obo/CL_0000663 UBERON:0009617 biolink:AnatomicalEntity head paraxial mesoderm Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. go-plus.json somitomere|cephalic paraxial mesoderm|cranial paraxial mesoderm|head paraxial mesenchyme|cephalic paraxial mesenchyme|somitomeric mesoderm|cranial paraxial mesenchyme http://purl.obolibrary.org/obo/UBERON_0009617 CHEBI:76061 biolink:ChemicalSubstance 1-O-palmitylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76061 chebi_ph7_3 UBERON:0009618 biolink:AnatomicalEntity trunk paraxial mesoderm go-plus.json trunk paraxial mesenchyme|trunk and cervical paraxial mesenchyme http://purl.obolibrary.org/obo/UBERON_0009618 CHEBI:76062 biolink:ChemicalSubstance 1-O-palmityl-3-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76062 chebi_ph7_3 GO:0015710 biolink:BiologicalProcess tellurite transport The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015710 CHEBI:76068 biolink:ChemicalSubstance N,O-dioleoylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76068 chebi_ph7_3 CHEBI:76065 biolink:ChemicalSubstance 1-oleoyl-2-palmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_76065 chebi_ph7_3 GO:0050121 biolink:MolecularActivity N-acylglucosamine 2-epimerase activity Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine. EC:5.1.3.8|Reactome:R-HSA-6803761|MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN|RHEA:19033 go-plus.json N-acetylglucosamine 2-epimerase activity|N-acyl-D-glucosamine 2-epimerase activity|acylglucosamine 2-epimerase activity|N-acetyl-D-glucosamine 2-epimerase activity|GlcNAc 2-epimerase activity http://purl.obolibrary.org/obo/GO_0050121 GO:0050122 biolink:MolecularActivity N-acylhexosamine oxidase activity Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+). MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN|EC:1.1.3.29|KEGG_REACTION:R01203|RHEA:13029 go-plus.json N-acyl-D-hexosamine oxidase activity|N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity|N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050122 UBERON:0009610 biolink:AnatomicalEntity forebrain neural plate A neural plate that develops_from a future forebrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009610 GO:0050120 biolink:MolecularActivity N-acetylhexosamine 1-dehydrogenase activity Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH. EC:1.1.1.240|MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN|KEGG_REACTION:R01202|RHEA:23144 go-plus.json N-acetylhexosamine dehydrogenase activity|N-acetyl-D-hexosamine dehydrogenase activity|N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0050120 UBERON:0009611 biolink:AnatomicalEntity midbrain neural plate A neural plate that develops_from a presumptive midbrain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0009611 GO:0050136 biolink:MolecularActivity NADH dehydrogenase (quinone) activity Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol. EC:1.6.5.11|RHEA:46160|MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN go-plus.json D-diaphorase activity|reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity|NADH:(quinone-acceptor) oxidoreductase activity|NADH-quinone oxidoreductase activity|DPNH-menadione reductase activity http://purl.obolibrary.org/obo/GO_0050136 GO:0050137 biolink:MolecularActivity NADPH peroxidase activity Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+). MetaCyc:NADPH-PEROXIDASE-RXN|RHEA:15173|EC:1.11.1.2|KEGG_REACTION:R00113 go-plus.json triphosphopyridine nucleotide peroxidase activity|NADP peroxidase activity|NADPH:hydrogen-peroxide oxidoreductase activity|TPNH peroxidase activity|nicotinamide adenine dinucleotide phosphate peroxidase activity|TPN peroxidase activity http://purl.obolibrary.org/obo/GO_0050137 GO:0050134 biolink:MolecularActivity N6-methyl-lysine oxidase activity Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2). RHEA:23200|EC:1.5.3.4|MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN|KEGG_REACTION:R00612 go-plus.json N(6)-methyllysine oxidase activity|N6-methyllysine oxidase activity|epsilon-N-methyllysine demethylase activity|N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)|epsilon-alkyl-L-lysine:oxygen oxidoreductase activity|epsilon-alkyllysinase activity|6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0050134 GO:0050135 biolink:MolecularActivity NAD(P)+ nucleosidase activity Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide. EC:3.2.2.6|MetaCyc:NADP+-NUCLEOSIDASE-RXN go-plus.json NAD(P)(+) nucleosidase activity|nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity|triphosphopyridine nucleotidase activity|NAD(P) nucleosidase activity|nicotinamide adenine dinucleotide (phosphate) nucleosidase activity|NAD(P)+ glycohydrolase activity|NAD(P)ase activity http://purl.obolibrary.org/obo/GO_0050135 CHEBI:27027 biolink:ChemicalSubstance micronutrient go-plus.json http://purl.obolibrary.org/obo/CHEBI_27027 GO:0050138 biolink:MolecularActivity nicotinate dehydrogenase activity Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH. RHEA:12236|EC:1.17.1.5|MetaCyc:RXN-7637|MetaCyc:NICOTINATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01720 go-plus.json nicotinic acid hydroxylase activity|nicotinate hydroxylase activity|nicotinate:NADP+ 6-oxidoreductase (hydroxylating) http://purl.obolibrary.org/obo/GO_0050138 GO:0050139 biolink:MolecularActivity nicotinate-N-glucosyltransferase activity Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP. RHEA:19437|EC:2.4.1.196|MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R01722 go-plus.json nicotinate glucosyltransferase activity|UDP-glucose:nicotinate N-glucosyltransferase activity|UDP-glucose:nicotinic acid-N-glucosyltransferase activity|uridine diphosphoglucose-nicotinate N-glucosyltransferase activity|UDPglucose:nicotinate N-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0050139 CL:0000677 biolink:Cell gut absorptive cell Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. go-plus.json http://purl.obolibrary.org/obo/CL_0000677 CHEBI:27023 biolink:ChemicalSubstance toluene-4-sulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27023 chebi_ph7_3 CHEBI:27024 biolink:ChemicalSubstance toluenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_27024 CL:0000678 biolink:Cell commissural neuron go-plus.json http://purl.obolibrary.org/obo/CL_0000678 CL:0000679 biolink:Cell glutamatergic neuron go-plus.json http://purl.obolibrary.org/obo/CL_0000679 CHEBI:27026 biolink:ChemicalSubstance toxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_27026 GO:0015726 biolink:BiologicalProcess L-idonate transmembrane transport The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. go-plus.json L-idonate transport http://purl.obolibrary.org/obo/GO_0015726 GO:0015727 biolink:BiologicalProcess lactate transport The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. go-plus.json http://purl.obolibrary.org/obo/GO_0015727 GO:0015728 biolink:BiologicalProcess mevalonate transport The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015728 CHEBI:27021 biolink:ChemicalSubstance toluate go-plus.json http://purl.obolibrary.org/obo/CHEBI_27021 GO:0015729 biolink:BiologicalProcess oxaloacetate transport The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015729 GO:0015722 biolink:BiologicalProcess canalicular bile acid transport Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. go-plus.json http://purl.obolibrary.org/obo/GO_0015722 CHEBI:76070 biolink:ChemicalSubstance O-oleoylanandamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_76070 chebi_ph7_3 GO:0015723 biolink:BiologicalProcess bilirubin transport The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015723 UBERON:0009602 biolink:AnatomicalEntity left lung associated mesenchyme Mesenchyme that is part of a developing left lung. go-plus.json left lung mesenchyme http://purl.obolibrary.org/obo/UBERON_0009602 CL:0000670 biolink:Cell primordial germ cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. go-plus.json gonocyte|primitive germ cell http://purl.obolibrary.org/obo/CL_0000670 CHEBI:76071 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76071 chebi_ph7_3 CL:0000671 biolink:Cell centripetally migrating follicle cell go-plus.json http://purl.obolibrary.org/obo/CL_0000671 GO:0015724 biolink:BiologicalProcess formate transport The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015724 UBERON:0009603 biolink:AnatomicalEntity right lung associated mesenchyme Mesenchyme that is part of a developing right lung. go-plus.json right lung mesenchyme http://purl.obolibrary.org/obo/UBERON_0009603 GO:0015725 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0015725 CHEBI:76074 biolink:ChemicalSubstance 1-O-stearoyl-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76074 chebi_ph7_3 CHEBI:42646 biolink:ChemicalSubstance flaviolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_42646 GO:0015720 biolink:BiologicalProcess allantoin transport The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json allantoin transmembrane transport|allantoin/allantoate transport http://purl.obolibrary.org/obo/GO_0015720 CL:0000675 biolink:Cell female gamete A mature sexual reproductive cell of the female germline. go-plus.json http://purl.obolibrary.org/obo/CL_0000675 CHEBI:76072 biolink:ChemicalSubstance nicotinic acid-adenine dinucleotide phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_76072 GO:0015721 biolink:BiologicalProcess bile acid and bile salt transport The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json bile acid transport|bile salt transport http://purl.obolibrary.org/obo/GO_0015721 CHEBI:76073 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76073 chebi_ph7_3 CHEBI:76078 biolink:ChemicalSubstance 2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76078 chebi_ph7_3 CHEBI:76079 biolink:ChemicalSubstance 2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76079 chebi_ph7_3 CL:0009004 biolink:Cell retinal cell Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. go-plus.json http://purl.obolibrary.org/obo/CL_0009004 CHEBI:76076 biolink:ChemicalSubstance 2-stearoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76076 chebi_ph7_3 CHEBI:76077 biolink:ChemicalSubstance 1-O-palmitoyl-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_76077 chebi_ph7_3 GO:0050132 biolink:MolecularActivity N-methylalanine dehydrogenase activity Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate. KEGG_REACTION:R01584|MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN|EC:1.4.1.17|RHEA:21768 go-plus.json N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating) http://purl.obolibrary.org/obo/GO_0050132 GO:0050133 biolink:MolecularActivity N6-hydroxylysine O-acetyltransferase activity Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA. RHEA:22388|KEGG_REACTION:R03168|EC:2.3.1.102|MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN go-plus.json N6-hydroxylysine acetylase activity|N6-hydroxylysine:acetyl CoA N6-transacetylase activity|N(6)-hydroxylysine acetylase activity|acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity|acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0050133 GO:0050130 biolink:MolecularActivity N-methyl-2-oxoglutaramate hydrolase activity Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium. MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN|EC:3.5.1.36|RHEA:24108|KEGG_REACTION:R01587 go-plus.json 5-hydroxy-N-methylpyroglutamate synthase activity|N-methyl-2-oxoglutaramate methylamidohydrolase activity http://purl.obolibrary.org/obo/GO_0050130 CL:0009001 biolink:Cell compound eye retinal cell Any cell in the compound eye, a light sensing organ composed of ommatidia. go-plus.json http://purl.obolibrary.org/obo/CL_0009001 GO:0050131 biolink:MolecularActivity N-methyl-L-amino-acid oxidase activity Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2. RHEA:11472|MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN|EC:1.5.3.2 go-plus.json N-methylamino acid oxidase activity|N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0050131 GO:1990233 biolink:CellularComponent intramolecular phosphotransferase complex A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule. go-plus.json http://purl.obolibrary.org/obo/GO_1990233 GO:1990234 biolink:CellularComponent transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). go-plus.json http://purl.obolibrary.org/obo/GO_1990234 GO:1990235 biolink:CellularComponent diamine N-acetyltransferase complex A protein complex which is capable of diamine N-acetyltransferase activity. go-plus.json SAT tetramer|SAT complex|spermidine acetyltransferase complex http://purl.obolibrary.org/obo/GO_1990235 GO:1990236 biolink:BiologicalProcess proteasome core complex import into nucleus The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_1990236 GO:1990230 biolink:CellularComponent iron-sulfur cluster transfer complex A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor). go-plus.json IscA complex|Fe-S cluster transfer complex|SufA dimer|SufA complex http://purl.obolibrary.org/obo/GO_1990230 GO:1990231 biolink:CellularComponent STING complex A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response. go-plus.json stimulator of interferon genes complex http://purl.obolibrary.org/obo/GO_1990231 GO:1990232 biolink:CellularComponent phosphomannomutase complex A protein complex capable of phosphomannomutase activity. go-plus.json PMM-2 complex|PMM-1 complex|PMM-2 dimer|PMM-1 dimer http://purl.obolibrary.org/obo/GO_1990232 BFO:0000050 biolink:OntologyClass part of a core relation that holds between a part and its whole BFO:0000050 go-plus.json http://purl.obolibrary.org/obo/BFO_0000050 BFO:0000055 biolink:OntologyClass realizes BFO:0000055 go-plus.json http://purl.obolibrary.org/obo/BFO_0000055 BFO:0000051 biolink:OntologyClass has part a core relation that holds between a whole and its part BFO:0000051 go-plus.json http://purl.obolibrary.org/obo/BFO_0000051 GO:1990237 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990237 GO:1990238 biolink:MolecularActivity double-stranded DNA endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks. go-plus.json dsDNA-specific endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_1990238 GO:1990239 biolink:MolecularActivity steroid hormone binding Binding to a steroid hormone. go-plus.json http://purl.obolibrary.org/obo/GO_1990239 BFO:0000054 biolink:OntologyClass realized in BFO:0000054 go-plus.json http://purl.obolibrary.org/obo/BFO_0000054 GO:1990244 biolink:MolecularActivity histone kinase activity (H2A-T120 specific) Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A. go-plus.json histone threonine kinase activity (H2A-T120 specific) http://purl.obolibrary.org/obo/GO_1990244 GO:1990245 biolink:BiologicalProcess histone H2A-T120 phosphorylation The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone. go-plus.json histone H2AT120 phosphorylation|histone H2A phosphorylation at T120 http://purl.obolibrary.org/obo/GO_1990245 GO:1990246 biolink:CellularComponent uniplex complex A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE. go-plus.json mitochondrial uniporter complex|mitochondrial uniporter holocomplex http://purl.obolibrary.org/obo/GO_1990246 GO:1990247 biolink:MolecularActivity N6-methyladenosine-containing RNA binding Binding to an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs. go-plus.json http://purl.obolibrary.org/obo/GO_1990247 GO:1990240 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1990240 GO:1990241 biolink:CellularComponent obsolete nucleotide binding complex OBSOLETE. A protein complex that interacts selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. An example of this is STING in E. coli (Q86WV6). go-plus.json nucleotide binding complex http://purl.obolibrary.org/obo/GO_1990241 GO:1990242 biolink:CellularComponent obsolete innate immune response complex OBSOLETE. A protein complex involved in the innate immune response. go-plus.json innate immune response complex http://purl.obolibrary.org/obo/GO_1990242 GO:1990243 biolink:CellularComponent atf1-pcr1 complex A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE). go-plus.json http://purl.obolibrary.org/obo/GO_1990243 BFO:0000040 biolink:OntologyClass material entity An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. go-plus.json http://purl.obolibrary.org/obo/BFO_0000040 GO:1990248 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to DNA damage Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_1990248 GO:1990249 biolink:CellularComponent nucleotide-excision repair, DNA damage recognition complex A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex. go-plus.json http://purl.obolibrary.org/obo/GO_1990249 GO:1990255 biolink:BiologicalProcess subsynaptic reticulum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1990255 GO:1990256 biolink:BiologicalProcess signal clustering Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response. go-plus.json ligand clustering http://purl.obolibrary.org/obo/GO_1990256 GO:1990257 biolink:CellularComponent piccolo-bassoon transport vesicle A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon. go-plus.json PTV http://purl.obolibrary.org/obo/GO_1990257 GO:1990258 biolink:BiologicalProcess histone glutamine methylation The modification of a histone by addition of a methyl group to an glutamine residue. go-plus.json http://purl.obolibrary.org/obo/GO_1990258 GO:1990251 biolink:CellularComponent nuclear exosome focus An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome. go-plus.json Mmi1 nuclear focus|nuclear body http://purl.obolibrary.org/obo/GO_1990251 GO:0001198 biolink:BiologicalProcess negative regulation of mating-type specific transcription from RNA polymerase II promoter Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. go-plus.json down regulation of RNA polymerase II transcription, mating-type specific|downregulation of RNA polymerase II transcription, mating-type specific|down-regulation of RNA polymerase II transcription, mating-type specific|inhibition of RNA polymerase II transcription, mating-type specific http://purl.obolibrary.org/obo/GO_0001198 GO:0001199 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001199 GO:1990252 biolink:CellularComponent Syp1 complex A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis. go-plus.json Syp1 dimer http://purl.obolibrary.org/obo/GO_1990252 GO:1990253 biolink:BiologicalProcess cellular response to leucine starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine. go-plus.json http://purl.obolibrary.org/obo/GO_1990253 GO:1990254 biolink:MolecularActivity keratin filament binding Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_1990254 GO:0001194 biolink:BiologicalProcess maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a bacterial-type RNA polymerase promoter. go-plus.json maintenance of transcriptional fidelity during DNA-dependent transcription elongation from bacterial-type RNA polymerase promoter http://purl.obolibrary.org/obo/GO_0001194 GO:0001195 biolink:BiologicalProcess maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter. go-plus.json maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_0001195 GO:0001196 biolink:BiologicalProcess regulation of mating-type specific transcription from RNA polymerase II promoter Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0001196 GO:0001197 biolink:BiologicalProcess positive regulation of mating-type specific transcription from RNA polymerase II promoter Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter. go-plus.json up-regulation of transcription from an RNA polymerase II promoter, mating-type specific|activation of transcription from an RNA polymerase II promoter, mating-type specific|up regulation of transcription from an RNA polymerase II promoter, mating-type specific|upregulation of transcription from an RNA polymerase II promoter, mating-type specific|stimulation of transcription from an RNA polymerase II promoter, mating-type specific http://purl.obolibrary.org/obo/GO_0001197 GO:1990250 biolink:CellularComponent transcription-coupled nucleotide-excision repair, DNA damage recognition complex A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex. go-plus.json http://purl.obolibrary.org/obo/GO_1990250 GO:0001190 biolink:MolecularActivity obsolete transcriptional activator activity, RNA polymerase II transcription factor binding OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription activator activity http://purl.obolibrary.org/obo/GO_0001190 GO:0001191 biolink:MolecularActivity obsolete transcriptional repressor activity, RNA polymerase II transcription factor binding OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json RNA polymerase II transcription repressor activity|RNA polymerase II transcription factor binding transcription repressor activity|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription http://purl.obolibrary.org/obo/GO_0001191 GO:0001192 biolink:BiologicalProcess maintenance of transcriptional fidelity during DNA-templated transcription elongation Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template. go-plus.json maintenance of transcriptional fidelity during DNA-dependent transcription elongation http://purl.obolibrary.org/obo/GO_0001192 GO:0001193 biolink:BiologicalProcess maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter. go-plus.json maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0001193 CHEBI:52092 biolink:ChemicalSubstance ethoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_52092 CHEBI:134489 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134489 CHEBI:52094 biolink:ChemicalSubstance peroxy acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52094 CHEBI:134486 biolink:ChemicalSubstance dimethylphosphatidylethanolamine 32:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134486 CHEBI:52090 biolink:ChemicalSubstance methoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_52090 CHEBI:134481 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134481 CHEBI:134484 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_134484 GO:1990259 biolink:MolecularActivity histone-glutamine methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine. go-plus.json http://purl.obolibrary.org/obo/GO_1990259 CHEBI:134482 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134482 GO:1990266 biolink:BiologicalProcess neutrophil migration The movement of a neutrophil within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_1990266 GO:1990267 biolink:BiologicalProcess response to transition metal nanoparticle Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle. go-plus.json response to neutral metal atoms|response to colloidal metal http://purl.obolibrary.org/obo/GO_1990267 GO:1990268 biolink:BiologicalProcess response to gold nanoparticle Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1990268 GO:1990269 biolink:MolecularActivity RNA polymerase II C-terminal domain phosphoserine binding Binding to phosphorylated serine residues in the C-terminal domain of RNA polymerase II. go-plus.json RNA Pol II C-terminal domain phosphoserine binding|RNAP II C-terminal domain phosphoserine binding http://purl.obolibrary.org/obo/GO_1990269 GO:1990262 biolink:BiologicalProcess anti-Mullerian hormone signaling pathway A series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_1990262 GO:1990263 biolink:BiologicalProcess spore wall assembly MAPK cascade A MAPK cascade that occurs as a result of deprivation of nourishment. go-plus.json MAPK cascade involved in nutrient response signaling|MAPK cascade in response to starvation http://purl.obolibrary.org/obo/GO_1990263 GO:1990264 biolink:BiologicalProcess peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1990264 GO:1990265 biolink:CellularComponent platelet-derived growth factor complex A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD). go-plus.json PDGF complex|PDGF-AB dimer|PDGF-DD dimer|PDGF-BB dimer|PDGF-CC dimer|PDGF-AA dimer http://purl.obolibrary.org/obo/GO_1990265 GO:1990260 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling. go-plus.json http://purl.obolibrary.org/obo/GO_1990260 GO:1990261 biolink:BiologicalProcess pre-mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA). go-plus.json pre-mRNA decay|unspliced RNA decay http://purl.obolibrary.org/obo/GO_1990261 CHEBI:134499 biolink:ChemicalSubstance 13,14-dihydro-15-oxoprostaglandin E1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134499 BFO:0000066 biolink:OntologyClass occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t BFO:0000066 go-plus.json http://purl.obolibrary.org/obo/BFO_0000066 CHEBI:134491 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134491 BFO:0000067 biolink:OntologyClass contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t BFO:0000067 go-plus.json http://purl.obolibrary.org/obo/BFO_0000067 CHEBI:134492 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134492 BFO:0000062 biolink:OntologyClass preceded_by The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. BFO:0000062 go-plus.json is preceded by|takes place after http://purl.obolibrary.org/obo/BFO_0000062 CHEBI:134495 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134495 BFO:0000063 biolink:OntologyClass precedes x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. BFO:0000063 go-plus.json http://purl.obolibrary.org/obo/BFO_0000063 CHEBI:52086 biolink:ChemicalSubstance glyceollin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_52086 chebi_ph7_3 CHEBI:134493 biolink:ChemicalSubstance phosphatidylethanolamine 40:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134493 BFO:0000019 biolink:OntologyClass quality go-plus.json http://purl.obolibrary.org/obo/BFO_0000019 GO:0001176 biolink:BiologicalProcess transcriptional start site selection at bacterial-type RNA polymerase promoter Any process involved in the selection of the specific location within the template strand of a bacterial-type RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0001176 BFO:0000015 biolink:OntologyClass process An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. go-plus.json http://purl.obolibrary.org/obo/BFO_0000015 GO:0001177 biolink:BiologicalProcess regulation of transcription open complex formation at RNA polymerase II promoter Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. go-plus.json regulation of transcriptional open complex formation at RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0001177 BFO:0000016 biolink:OntologyClass disposition go-plus.json http://purl.obolibrary.org/obo/BFO_0000016 GO:0001178 biolink:BiologicalProcess regulation of transcriptional start site selection at RNA polymerase II promoter Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. go-plus.json regulation of transcriptional start site selection at RNA polymerase II promoter|regulation of transcription start site selection at RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0001178 BFO:0000017 biolink:OntologyClass realizable entity A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. go-plus.json http://purl.obolibrary.org/obo/BFO_0000017 GO:0001179 biolink:MolecularActivity RNA polymerase I general transcription initiation factor binding Binding to an RNA polymerase I transcription factor, a protein required to initiate or regulate transcription by RNA polymerase I. go-plus.json RNA polymerase I transcription factor binding http://purl.obolibrary.org/obo/GO_0001179 GO:0001172 biolink:BiologicalProcess transcription, RNA-templated The cellular synthesis of RNA on a template of RNA. go-plus.json transcription, RNA-dependent http://purl.obolibrary.org/obo/GO_0001172 GO:0001173 biolink:BiologicalProcess DNA-templated transcriptional start site selection Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. go-plus.json DNA-dependent transcriptional start site selection http://purl.obolibrary.org/obo/GO_0001173 GO:0001174 biolink:BiologicalProcess transcriptional start site selection at RNA polymerase II promoter Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0001174 GO:0001175 biolink:BiologicalProcess transcriptional start site selection at RNA polymerase III promoter Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0001175 GO:0001170 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase I enhancer sequence-specific binding OBSOLETE. Binding to a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I. go-plus.json RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001170 GO:0001171 biolink:BiologicalProcess reverse transcription A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis. Wikipedia:Reverse_transcription go-plus.json http://purl.obolibrary.org/obo/GO_0001171 CHEBI:52070 biolink:ChemicalSubstance senecionine N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_52070 chebi_ph7_3 CHEBI:134467 biolink:ChemicalSubstance L-vinylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_134467 chebi_ph7_3 CHEBI:134464 biolink:ChemicalSubstance [(2->6)-beta-D-fructofuranosyl-]n alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_134464 chebi_ph7_3 CHEBI:52079 biolink:ChemicalSubstance N-acetyl-D-hexosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52079 CHEBI:52075 biolink:ChemicalSubstance all-trans-13,14-dihydroretinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52075 chebi_ph7_3 CHEBI:52076 biolink:ChemicalSubstance gibberellin A3 O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_52076 GO:1990200 biolink:CellularComponent SsuD-SsuE complex A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation. go-plus.json two-component alkanesulfonate monooxygenase system http://purl.obolibrary.org/obo/GO_1990200 GO:1990201 biolink:CellularComponent alkanesulfonate monooxygenase complex A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer. go-plus.json SsuD complex http://purl.obolibrary.org/obo/GO_1990201 GO:1990202 biolink:CellularComponent FMN reductase complex A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer. go-plus.json FMN reductase complex, NAD(P)H-dependent|FMN oxidoreductase complex, NAD(P)H-dependent|flavin oxidoreductase complex, NAD(P)H-dependent|SsuE complex http://purl.obolibrary.org/obo/GO_1990202 GO:1990203 biolink:CellularComponent MdtBC Complex A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane. go-plus.json multidrug efflux pump MdtBC http://purl.obolibrary.org/obo/GO_1990203 BFO:0000004 biolink:OntologyClass independent continuant A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. go-plus.json http://purl.obolibrary.org/obo/BFO_0000004 GO:0001187 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001187 GO:0001188 biolink:BiologicalProcess RNA polymerase I preinitiation complex assembly The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter. go-plus.json RNA polymerase I transcriptional preinitiation complex assembly|RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript|RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript http://purl.obolibrary.org/obo/GO_0001188 GO:0001189 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001189 GO:0001183 biolink:BiologicalProcess transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript by the addition of ribonucleotides catalyzed by RNA polymerase I. go-plus.json http://purl.obolibrary.org/obo/GO_0001183 GO:0001184 biolink:BiologicalProcess promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I at a promoter for the nuclear large ribosomal RNA (rRNA) transcript, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. go-plus.json http://purl.obolibrary.org/obo/GO_0001184 GO:0001185 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001185 GO:0001186 biolink:MolecularActivity obsolete RNA polymerase I transcription regulator recruiting activity OBSOLETE. The function of binding to an RNA polymerase I (RNAP I) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation. go-plus.json transcription factor activity, RNA polymerase I transcription factor recruiting|RNA polymerase I transcription factor recruiting transcription factor activity|RNA polymerase I transcription factor recruiting activity http://purl.obolibrary.org/obo/GO_0001186 GO:0001180 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001180 GO:0001181 biolink:MolecularActivity RNA polymerase I general transcription initiation factor activity A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs. go-plus.json transcription factor activity, core RNA polymerase I binding|RNA polymerase I transcription general initiation factor activity|core RNA polymerase I binding transcription factor activity|general RNA polymerase I transcription factor activity http://purl.obolibrary.org/obo/GO_0001181 GO:0001182 biolink:BiologicalProcess promoter clearance from RNA polymerase I promoter Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. go-plus.json http://purl.obolibrary.org/obo/GO_0001182 CHEBI:134477 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134477 CHEBI:134478 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134478 CHEBI:52061 biolink:ChemicalSubstance 5-methoxyfurocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52061 chebi_ph7_3 GO:1990208 biolink:BiologicalProcess positive regulation by symbiont of RNA levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990208 GO:1990209 biolink:BiologicalProcess negative regulation by symbiont of RNA levels in host Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990209 BFO:0000002 biolink:OntologyClass continuant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. go-plus.json http://purl.obolibrary.org/obo/BFO_0000002 CHEBI:52069 biolink:ChemicalSubstance 3,5-dihydroxybiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_52069 chebi_ph7_3 BFO:0000003 biolink:OntologyClass occurrent An entity that has temporal parts and that happens, unfolds or develops through time. go-plus.json http://purl.obolibrary.org/obo/BFO_0000003 GO:1990204 biolink:CellularComponent oxidoreductase complex Any protein complex that possesses oxidoreductase activity. go-plus.json redox complex|oxidation-reduction complex http://purl.obolibrary.org/obo/GO_1990204 goslim_metagenomics GO:1990205 biolink:CellularComponent taurine dioxygenase complex A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD. go-plus.json alpha-ketoglutarate-dependent taurine dioxygenase complex|2-aminoethanesulfonate dioxygenase complex|TauD complex http://purl.obolibrary.org/obo/GO_1990205 GO:1990206 biolink:MolecularActivity jasmonyl-Ile conjugate hydrolase activity Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine. go-plus.json JA-Ile hydrolase http://purl.obolibrary.org/obo/GO_1990206 CHEBI:134471 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_134471 GO:1990207 biolink:CellularComponent EmrE multidrug transporter complex A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer. go-plus.json EmrE complex http://purl.obolibrary.org/obo/GO_1990207 CHEBI:134472 biolink:ChemicalSubstance N-acyl-alpha-aminoacyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_134472 GO:0001158 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001158 GO:1990211 biolink:BiologicalProcess positive regulation by symbiont of jasmonic acid levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990211 GO:0001159 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001159 GO:1990212 biolink:BiologicalProcess positive regulation by symbiont of ethylene levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990212 GO:1990213 biolink:BiologicalProcess negative regulation by symbiont of salicylic acid levels in host Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990213 GO:1990214 biolink:BiologicalProcess obsolete negative regulation by symbiont of host protein levels OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990214 GO:0001154 biolink:MolecularActivity TFIIIB-class transcription factor complex binding Binding to a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III. go-plus.json TFIIIB-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001154 GO:0001155 biolink:MolecularActivity TFIIIA-class transcription factor binding Binding to an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0001155 GO:0001156 biolink:MolecularActivity TFIIIC-class transcription factor complex binding Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III. go-plus.json TFIIIC-class transcription factor binding http://purl.obolibrary.org/obo/GO_0001156 GO:0001157 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001157 GO:1990210 biolink:BiologicalProcess positive regulation by symbiont of indole acetic acid levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of IAA levels in host|positive regulation by symbiont of auxin levels in host http://purl.obolibrary.org/obo/GO_1990210 GO:0001150 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001150 GO:0001151 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001151 GO:0001152 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting OBSOLETE. The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter. go-plus.json TFIIIA activity|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity|type 1 RNA polymerase III promoter recognition http://purl.obolibrary.org/obo/GO_0001152 GO:0001153 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase III transcription factor recruiting OBSOLETE. The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III. go-plus.json RNA polymerase III transcription factor recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001153 CHEBI:27096 biolink:ChemicalSubstance trichlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_27096 CHEBI:27097 biolink:ChemicalSubstance trichlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_27097 GO:0015799 biolink:BiologicalProcess propanediol transport The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects. go-plus.json http://purl.obolibrary.org/obo/GO_0015799 CHEBI:52050 biolink:ChemicalSubstance (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52050 CHEBI:52051 biolink:ChemicalSubstance benzyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_52051 chebi_ph7_3 GO:0015795 biolink:BiologicalProcess sorbitol transport The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose. go-plus.json glucitol transport http://purl.obolibrary.org/obo/GO_0015795 CHEBI:134448 biolink:ChemicalSubstance phosphatidylglycerol 38:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134448 GO:0015796 biolink:BiologicalProcess galactitol transport The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. go-plus.json http://purl.obolibrary.org/obo/GO_0015796 GO:0015797 biolink:BiologicalProcess mannitol transport The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group. go-plus.json http://purl.obolibrary.org/obo/GO_0015797 GO:0015798 biolink:BiologicalProcess myo-inositol transport The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms. go-plus.json vitamin Bh transport http://purl.obolibrary.org/obo/GO_0015798 GO:0015791 biolink:BiologicalProcess polyol transport The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0015791 goslim_pir GO:1990219 biolink:BiologicalProcess obsolete positive regulation by symbiont of host protein levels OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990219 GO:0015792 biolink:BiologicalProcess arabinitol transmembrane transport The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. go-plus.json arabitol transport|arabinitol transport http://purl.obolibrary.org/obo/GO_0015792 CHEBI:52057 biolink:ChemicalSubstance N-acetylphosphinothricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52057 BFO:0000034 biolink:OntologyClass function go-plus.json http://purl.obolibrary.org/obo/BFO_0000034 GO:0015793 biolink:BiologicalProcess glycerol transport The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. go-plus.json http://purl.obolibrary.org/obo/GO_0015793 CHEBI:52058 biolink:ChemicalSubstance 5-hydroxyfurocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_52058 chebi_ph7_3 GO:0015794 biolink:BiologicalProcess glycerol-3-phosphate transmembrane transport The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol. go-plus.json glycerol-3-phosphate transport http://purl.obolibrary.org/obo/GO_0015794 GO:1990215 biolink:BiologicalProcess negative regulation by symbiont of host intracellular transport Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990215 CHEBI:52052 biolink:ChemicalSubstance phenylacetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_52052 chebi_ph7_3 GO:1990216 biolink:BiologicalProcess positive regulation by symbiont of host transcription Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990216 GO:1990217 biolink:BiologicalProcess suppression by symbiont of host phytoalexin production Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host phytoalexin production http://purl.obolibrary.org/obo/GO_1990217 GO:0015790 biolink:BiologicalProcess UDP-xylose transmembrane transport The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate. go-plus.json UDP-xylose transport http://purl.obolibrary.org/obo/GO_0015790 GO:1990218 biolink:BiologicalProcess positive regulation by symbiont of abscisic acid levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990218 GO:0001169 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase I CORE element sequence-specific binding OBSOLETE. Binding to CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I. go-plus.json RNA polymerase I core promoter sequence-specific DNA binding transcription factor|RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001169 GO:1990222 biolink:CellularComponent ProVWX complex The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions. go-plus.json ATP-binding cassette (ABC) transporter complex ProVWX http://purl.obolibrary.org/obo/GO_1990222 GO:1990223 biolink:BiologicalProcess positive regulation by symbiont of cytokinin levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_1990223 GO:1990224 biolink:MolecularActivity NMN phosphatase activity Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate. RHEA:30815 go-plus.json nicotinamide mononucleotide phosphatase activity|beta-nicotinamide D-ribonucleotide phosphatase activity http://purl.obolibrary.org/obo/GO_1990224 GO:1990225 biolink:CellularComponent rhoptry neck Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion. go-plus.json http://purl.obolibrary.org/obo/GO_1990225 GO:0001165 biolink:MolecularActivity RNA polymerase I cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element). go-plus.json RNA polymerase I enhancer sequence-specific DNA binding|RNA polymerase I upstream element sequence-specific DNA binding|RNA polymerase I upstream control element sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0001165 CHEBI:52049 biolink:ChemicalSubstance tetrachlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52049 GO:0001166 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001166 GO:1990220 biolink:CellularComponent GroEL-GroES complex Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins. go-plus.json bacterial chaperonin complex|bacterial chaperonin ATPase complex http://purl.obolibrary.org/obo/GO_1990220 GO:0001167 biolink:MolecularActivity obsolete RNA polymerase I transcription factor activity, sequence-specific DNA binding OBSOLETE. Binding to a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. go-plus.json sequence-specific DNA binding RNA polymerase I transcription factor activity http://purl.obolibrary.org/obo/GO_0001167 UBERON:5002544 biolink:AnatomicalEntity digit plus metapodial segment A subdivision of the autopod consisting of digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. go-plus.json digit ray|digit ( phalanges plus metapodial) plus soft tissue|digit digitopodial subdivision|digit http://purl.obolibrary.org/obo/UBERON_5002544 GO:0001168 biolink:MolecularActivity obsolete transcription factor activity, RNA polymerase I upstream control element sequence-specific binding OBSOLETE. Binding to a upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I. go-plus.json RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0001168 GO:1990221 biolink:CellularComponent L-cysteine desulfurase complex A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer. go-plus.json IscS|SufS complex|NIFS|NifS http://purl.obolibrary.org/obo/GO_1990221 GO:0001161 biolink:MolecularActivity intronic transcription regulatory region sequence-specific DNA binding Binding to an intronic DNA sequence that regulates the transcription of the transcript it is contained within. go-plus.json intronic transcription regulatory region DNA binding http://purl.obolibrary.org/obo/GO_0001161 GO:0001162 biolink:MolecularActivity RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within. go-plus.json http://purl.obolibrary.org/obo/GO_0001162 GO:0001163 biolink:MolecularActivity RNA polymerase I transcription regulatory region sequence-specific DNA binding Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I. go-plus.json RNA polymerase I regulatory region DNA binding http://purl.obolibrary.org/obo/GO_0001163 GO:0001164 biolink:MolecularActivity RNA polymerase I core promoter sequence-specific DNA binding Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE. go-plus.json RNA polymerase I core promoter sequence-specific DNA binding|transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting|RNA polymerase I CORE element sequence-specific DNA binding|RNA polymerase I core element sequence-specific DNA binding|RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity http://purl.obolibrary.org/obo/GO_0001164 GO:0001160 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0001160 CHEBI:134456 biolink:ChemicalSubstance 12-oxo-20-hydroxyleukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_134456 CHEBI:134453 biolink:ChemicalSubstance 10-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_134453 CHEBI:52045 biolink:ChemicalSubstance 2-oxo-1,2-dihydroquinoline-4-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_52045 BFO:0000023 biolink:OntologyClass role A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. go-plus.json http://purl.obolibrary.org/obo/BFO_0000023 CHEBI:52048 biolink:ChemicalSubstance 2,3,5,6-tetrachlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_52048 GO:1990226 biolink:MolecularActivity histone methyltransferase binding Binding to a histone methyltransferase enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_1990226 GO:1990227 biolink:BiologicalProcess paranodal junction maintenance The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath. go-plus.json paranodal axoglial junction maintenance|paranodal septate maintenance|axoglial septate junction maintenance http://purl.obolibrary.org/obo/GO_1990227 GO:1990228 biolink:CellularComponent sulfurtransferase complex A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor). go-plus.json SufE dimer|SufE complex|ThiF-ThiS complex|sulfur transfer complex http://purl.obolibrary.org/obo/GO_1990228 BFO:0000020 biolink:OntologyClass specifically dependent continuant A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. go-plus.json http://purl.obolibrary.org/obo/BFO_0000020 CHEBI:52043 biolink:ChemicalSubstance 7-methyl-3-oxooct-6-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_52043 GO:1990229 biolink:CellularComponent iron-sulfur cluster assembly complex A protein complex capable of assembling an iron-sulfur (Fe-S) cluster. go-plus.json Fe-S cluster assembly complex|SufBCD complex http://purl.obolibrary.org/obo/GO_1990229 GO:0019460 biolink:BiologicalProcess glutamine catabolic process to fumarate The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate. go-plus.json glutamine degradation to fumarate|glutamine breakdown to fumarate|glutamate catabolic process to fumarate http://purl.obolibrary.org/obo/GO_0019460 GO:0044423 biolink:CellularComponent virion component Any constituent part of a virion, a complete fully infectious extracellular virus particle. Wikipedia:Virus go-plus.json complete virus particle|virion part|virion http://purl.obolibrary.org/obo/GO_0044423 goslim_chembl|gocheck_do_not_annotate|goslim_pir|goslim_metagenomics GO:0044424 biolink:CellularComponent obsolete intracellular part OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0044424 gocheck_do_not_annotate GO:0044421 biolink:CellularComponent obsolete extracellular region part OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite. NIF_Subcellular:sao9117790637 go-plus.json extracellular structure http://purl.obolibrary.org/obo/GO_0044421 gocheck_do_not_annotate GO:0044422 biolink:CellularComponent obsolete organelle part OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044422 gocheck_do_not_annotate GO:0044420 biolink:CellularComponent obsolete extracellular matrix component OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants). go-plus.json extracellular matrix part http://purl.obolibrary.org/obo/GO_0044420 gocheck_do_not_annotate GO:0044429 biolink:CellularComponent obsolete mitochondrial part OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. NIF_Subcellular:sao666410040 go-plus.json mitochondrial subcomponent|mitochondrion component http://purl.obolibrary.org/obo/GO_0044429 gocheck_do_not_annotate GO:0044427 biolink:CellularComponent obsolete chromosomal part OBSOLETE. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. go-plus.json chromosome component|chromosomal component|chromosome part http://purl.obolibrary.org/obo/GO_0044427 gocheck_do_not_annotate GO:0044428 biolink:CellularComponent obsolete nuclear part OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. NIF_Subcellular:sao1499850686 go-plus.json nucleus component|nuclear subcomponent http://purl.obolibrary.org/obo/GO_0044428 gocheck_do_not_annotate GO:0019458 biolink:BiologicalProcess methionine catabolic process via 2-oxobutanoate The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate. MetaCyc:PWY-701 go-plus.json methionine breakdown via 2-oxobutanoate|methionine degradation via 2-oxobutanoate http://purl.obolibrary.org/obo/GO_0019458 GO:0044425 biolink:CellularComponent obsolete membrane part OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0044425 gocheck_do_not_annotate GO:0044426 biolink:CellularComponent obsolete cell wall part OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. go-plus.json http://purl.obolibrary.org/obo/GO_0044426 gocheck_do_not_annotate GO:0019459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019459 GO:0019456 biolink:BiologicalProcess L-cysteine catabolic process via cystine, using cysteine transaminase The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3). go-plus.json L-cysteine breakdown via cystine, using cysteine transaminase|L-cysteine degradation via cystine, using cysteine transaminase http://purl.obolibrary.org/obo/GO_0019456 GO:0019457 biolink:BiologicalProcess methionine catabolic process to succinyl-CoA The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA. MetaCyc:METHIONINE-DEG1-PWY go-plus.json methionine degradation to succinyl-CoA|methionine breakdown to succinyl-CoA http://purl.obolibrary.org/obo/GO_0019457 GO:0019454 biolink:BiologicalProcess L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4). go-plus.json L-cysteine degradation via cystine, using glutathione-cystine transhydrogenase|L-cysteine breakdown via cystine, using glutathione-cystine transhydrogenase http://purl.obolibrary.org/obo/GO_0019454 GO:0019455 biolink:BiologicalProcess L-cysteine catabolic process via cystine, using cystine reductase The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6). go-plus.json L-cysteine breakdown via cystine, using cystine reductase|L-cysteine degradation via cystine, using cystine reductase http://purl.obolibrary.org/obo/GO_0019455 GO:0019452 biolink:BiologicalProcess L-cysteine catabolic process to taurine The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine. go-plus.json L-cysteine degradation to taurine|L-cysteine breakdown to taurine http://purl.obolibrary.org/obo/GO_0019452 GO:0019453 biolink:BiologicalProcess L-cysteine catabolic process via cystine The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine. go-plus.json L-cysteine degradation via cystine|L-cysteine breakdown via cystine http://purl.obolibrary.org/obo/GO_0019453 GO:0019450 biolink:BiologicalProcess L-cysteine catabolic process to pyruvate The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate. MetaCyc:LCYSDEG-PWY go-plus.json L-cysteine degradation to pyruvate|L-cysteine breakdown to pyruvate http://purl.obolibrary.org/obo/GO_0019450 GO:0019451 biolink:BiologicalProcess L-cysteine catabolic process to pyruvate, using cysteine dioxygenase The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20). MetaCyc:CYSTEINE-DEG-PWY go-plus.json L-cysteine degradation to pyruvate, using cysteine dioxygenase|L-cysteine breakdown to pyruvate, using cysteine dioxygenase http://purl.obolibrary.org/obo/GO_0019451 GO:0019470 biolink:BiologicalProcess 4-hydroxyproline catabolic process The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. MetaCyc:HYDROXYPRODEG-PWY go-plus.json 4-hydroxyproline degradation|4-hydroxyproline breakdown|4-hydroxyproline catabolism http://purl.obolibrary.org/obo/GO_0019470 GO:0019471 biolink:BiologicalProcess 4-hydroxyproline metabolic process The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls. go-plus.json 4-hydroxyproline metabolism http://purl.obolibrary.org/obo/GO_0019471 GO:0044434 biolink:CellularComponent obsolete chloroplast part OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. go-plus.json http://purl.obolibrary.org/obo/GO_0044434 gocheck_do_not_annotate CHEBI:140785 biolink:ChemicalSubstance R-cob(III)alamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140785 chebi_ph7_3 GO:0044435 biolink:CellularComponent obsolete plastid part OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. go-plus.json http://purl.obolibrary.org/obo/GO_0044435 gocheck_do_not_annotate GO:0044432 biolink:CellularComponent obsolete endoplasmic reticulum part OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. go-plus.json ER component http://purl.obolibrary.org/obo/GO_0044432 gocheck_do_not_annotate GO:0044433 biolink:CellularComponent obsolete cytoplasmic vesicle part OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044433 gocheck_do_not_annotate GO:0044430 biolink:CellularComponent obsolete cytoskeletal part OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice. NIF_Subcellular:sao1635329413 go-plus.json cytoskeleton component|cytoskeletal element http://purl.obolibrary.org/obo/GO_0044430 gocheck_do_not_annotate GO:0044431 biolink:CellularComponent obsolete Golgi apparatus part OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. NIF_Subcellular:sao624292949 go-plus.json Golgi subcomponent|Golgi component http://purl.obolibrary.org/obo/GO_0044431 gocheck_do_not_annotate GO:0044438 biolink:CellularComponent obsolete microbody part OBSOLETE. Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2). go-plus.json http://purl.obolibrary.org/obo/GO_0044438 gocheck_do_not_annotate GO:0044439 biolink:CellularComponent obsolete peroxisomal part OBSOLETE. Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2). go-plus.json peroxisome component http://purl.obolibrary.org/obo/GO_0044439 gocheck_do_not_annotate GO:0044436 biolink:CellularComponent obsolete thylakoid part OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0044436 gocheck_do_not_annotate GO:0019469 biolink:BiologicalProcess octopine catabolic process The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine. MetaCyc:OCTOPINEDEG-PWY go-plus.json octopine degradation|octopine breakdown|octopine catabolism http://purl.obolibrary.org/obo/GO_0019469 GO:0044437 biolink:CellularComponent obsolete vacuolar part OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. go-plus.json vacuole component http://purl.obolibrary.org/obo/GO_0044437 gocheck_do_not_annotate GO:0019467 biolink:BiologicalProcess ornithine catabolic process, by decarboxylation The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation. MetaCyc:ORNDEG-PWY go-plus.json ornithine degradation, by decarboxylation|ornithine breakdown, by decarboxylation http://purl.obolibrary.org/obo/GO_0019467 GO:0019468 biolink:BiologicalProcess nopaline catabolic process The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative. MetaCyc:NOPALINEDEG-PWY go-plus.json nopaline catabolism|nopaline breakdown|nopaline degradation http://purl.obolibrary.org/obo/GO_0019468 GO:0019465 biolink:BiologicalProcess aspartate transamidation The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group. MetaCyc:ASPARTATE-DEG1-PWY|MetaCyc:ASPARTATESYN-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019465 GO:0019466 biolink:BiologicalProcess ornithine catabolic process via proline The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline. MetaCyc:ORN-AMINOPENTANOATE-CAT-PWY go-plus.json ornithine degradation via proline|ornithine breakdown via proline http://purl.obolibrary.org/obo/GO_0019466 GO:0019463 biolink:BiologicalProcess glycine catabolic process to creatine The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine. MetaCyc:GLYCGREAT-PWY go-plus.json glycine degradation to creatine|glycine breakdown to creatine http://purl.obolibrary.org/obo/GO_0019463 GO:0019464 biolink:BiologicalProcess glycine decarboxylation via glycine cleavage system The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex. MetaCyc:GLYCLEAV-PWY go-plus.json glycine cleavage system http://purl.obolibrary.org/obo/GO_0019464 GO:0019461 biolink:BiologicalProcess glutamine catabolic process to fumarate, using glutamate synthase (NADPH) The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13). MetaCyc:GLUTAMINEFUM-PWY go-plus.json glutamine breakdown to fumarate, using glutamate synthase (NADPH)|glutamate catabolic process to fumarate, using glutamate synthase (NADPH)|glutamine degradation to fumarate, using glutamate synthase (NADPH) http://purl.obolibrary.org/obo/GO_0019461 GO:0019462 biolink:BiologicalProcess glutamine catabolic process to fumarate, using glutaminase The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2). MetaCyc:GLUTAMINDEG-PWY go-plus.json glutamate catabolic process to fumarate, using glutaminase|glutamine degradation to fumarate, using glutaminase|glutamine breakdown to fumarate, using glutaminase http://purl.obolibrary.org/obo/GO_0019462 GO:0044445 biolink:CellularComponent obsolete cytosolic part OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components. go-plus.json cytosol component http://purl.obolibrary.org/obo/GO_0044445 gocheck_do_not_annotate CHEBI:140773 biolink:ChemicalSubstance lysophosphatidylcholine P-16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_140773 chebi_ph7_3 CHEBI:140774 biolink:ChemicalSubstance 4-[(1->4)-alpha-D-glucosyl]n-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_140774 chebi_ph7_3 GO:0044446 biolink:CellularComponent obsolete intracellular organelle part OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044446 gocheck_do_not_annotate GO:0044443 biolink:CellularComponent obsolete pilus part OBSOLETE. Any constituent part of a pilus, a proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. go-plus.json pilus component|fimbrium component|fimbrial part http://purl.obolibrary.org/obo/GO_0044443 gocheck_do_not_annotate GO:0044444 biolink:CellularComponent obsolete cytoplasmic part OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. go-plus.json cytoplasm component http://purl.obolibrary.org/obo/GO_0044444 gocheck_do_not_annotate GO:0044441 biolink:CellularComponent obsolete ciliary part OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. go-plus.json flagellar part|microtubule-based flagellum part|flagellum part|cilial part|cilium part|flagellum component http://purl.obolibrary.org/obo/GO_0044441 gocheck_do_not_annotate GO:0044442 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044442 GO:0044440 biolink:CellularComponent obsolete endosomal part OBSOLETE. Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered. NIF_Subcellular:sao1683772610 go-plus.json endosomal subcomponent|endosome component http://purl.obolibrary.org/obo/GO_0044440 gocheck_do_not_annotate GO:0019438 biolink:BiologicalProcess aromatic compound biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. go-plus.json aromatic compound formation|aromatic compound biosynthesis|aromatic hydrocarbon biosynthesis|aromatic hydrocarbon biosynthetic process|aromatic compound anabolism|aromatic compound synthesis http://purl.obolibrary.org/obo/GO_0019438 GO:0044449 biolink:CellularComponent obsolete contractile fiber part OBSOLETE. Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. go-plus.json muscle fiber component|contractile fibre component|muscle fibre component http://purl.obolibrary.org/obo/GO_0044449 gocheck_do_not_annotate GO:0019439 biolink:BiologicalProcess aromatic compound catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring. go-plus.json aromatic compound catabolism|aromatic hydrocarbon catabolism|aromatic hydrocarbon catabolic process|aromatic compound degradation|aromatic compound breakdown http://purl.obolibrary.org/obo/GO_0019439 GO:0044447 biolink:CellularComponent obsolete axoneme part OBSOLETE. Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. go-plus.json axonemal part http://purl.obolibrary.org/obo/GO_0044447 gocheck_do_not_annotate GO:0019436 biolink:BiologicalProcess sophorosyloxydocosanoate catabolic process The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate. MetaCyc:SOPHOROSYLOXYDOCOSANOATE-DEG-PWY go-plus.json sophorosyloxydocosanoate degradation|sophorosyloxydocosanoate breakdown|sophorosyloxydocosanoate catabolism http://purl.obolibrary.org/obo/GO_0019436 CHEBI:140775 biolink:ChemicalSubstance 1-[(1->4)-alpha-D-glucosyl]n-alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140775 chebi_ph7_3 GO:0044448 biolink:CellularComponent obsolete cell cortex part OBSOLETE. Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0044448 gocheck_do_not_annotate GO:0019434 biolink:BiologicalProcess sophorosyloxydocosanoate metabolic process The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon. go-plus.json sophorosyloxydocosanoate metabolism http://purl.obolibrary.org/obo/GO_0019434 GO:0019435 biolink:BiologicalProcess sophorosyloxydocosanoate biosynthetic process The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate. MetaCyc:SOPHOROSYLOXYDOCOSANOATE-SYN-PWY go-plus.json sophorosyloxydocosanoate synthesis|sophorosyloxydocosanoate formation|sophorosyloxydocosanoate anabolism|sophorosyloxydocosanoate biosynthesis http://purl.obolibrary.org/obo/GO_0019435 GO:0019432 biolink:BiologicalProcess triglyceride biosynthetic process The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. MetaCyc:TRIGLSYN-PWY go-plus.json triglyceride anabolism|triglyceride synthesis|triglyceride formation|triacylglycerol biosynthetic process|triacylglycerol biosynthesis|triglyceride biosynthesis http://purl.obolibrary.org/obo/GO_0019432 GO:0019433 biolink:BiologicalProcess triglyceride catabolic process The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol. MetaCyc:LIPAS-PWY go-plus.json triacylglycerol catabolism|triacylglycerol catabolic process|triglyceride catabolism|triglyceride degradation|triglyceride breakdown http://purl.obolibrary.org/obo/GO_0019433 GO:0019430 biolink:BiologicalProcess removal of superoxide radicals Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2). MetaCyc:DETOX1-PWY go-plus.json cellular detoxification of superoxide radicals|removal of O2-|removal of oxygen free radicals http://purl.obolibrary.org/obo/GO_0019430 GO:0019431 biolink:BiologicalProcess acetyl-CoA biosynthetic process from ethanol The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde. MetaCyc:ETOH-ACETYLCOA-ANA-PWY go-plus.json acetyl-CoA formation from ethanol|acetyl-CoA synthesis from ethanol|acetyl-CoA anabolism from ethanol http://purl.obolibrary.org/obo/GO_0019431 GO:0044456 biolink:CellularComponent obsolete synapse part OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. NIF_Subcellular:sao1784069613 go-plus.json synaptic component http://purl.obolibrary.org/obo/GO_0044456 gocheck_do_not_annotate GO:0044457 biolink:CellularComponent obsolete cell septum part OBSOLETE. Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044457 gocheck_do_not_annotate GO:0044454 biolink:CellularComponent obsolete nuclear chromosome part OBSOLETE. Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. go-plus.json http://purl.obolibrary.org/obo/GO_0044454 gocheck_do_not_annotate GO:0044455 biolink:CellularComponent obsolete mitochondrial membrane part OBSOLETE. Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0044455 gocheck_do_not_annotate GO:0044452 biolink:CellularComponent obsolete nucleolar part OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. go-plus.json nucleolus component http://purl.obolibrary.org/obo/GO_0044452 gocheck_do_not_annotate GO:0044453 biolink:CellularComponent obsolete nuclear membrane part OBSOLETE. Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044453 gocheck_do_not_annotate GO:0044450 biolink:CellularComponent obsolete microtubule organizing center part OBSOLETE. Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow. go-plus.json MTOC component|microtubule organizing centre component http://purl.obolibrary.org/obo/GO_0044450 gocheck_do_not_annotate CHEBI:43098 biolink:ChemicalSubstance heptane go-plus.json http://purl.obolibrary.org/obo/CHEBI_43098 chebi_ph7_3 GO:0044451 biolink:CellularComponent obsolete nucleoplasm part OBSOLETE. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus. go-plus.json http://purl.obolibrary.org/obo/GO_0044451 gocheck_do_not_annotate GO:0019449 biolink:BiologicalProcess L-cysteine catabolic process to hypotaurine The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine. go-plus.json L-cysteine breakdown to hypotaurine|L-cysteine degradation to hypotaurine http://purl.obolibrary.org/obo/GO_0019449 GO:0044458 biolink:BiologicalProcess motile cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium. go-plus.json motile primary cilium assembly|motile primary cilia formation|nodal cilium formation|motile primary cilium formation|nodal cilium assembly|motile primary cilia assembly http://purl.obolibrary.org/obo/GO_0044458 GO:0019447 biolink:BiologicalProcess D-cysteine catabolic process The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin. go-plus.json D-cysteine degradation|D-cysteine breakdown|D-cysteine catabolism http://purl.obolibrary.org/obo/GO_0019447 CHEBI:140764 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140764 chebi_ph7_3 GO:0019448 biolink:BiologicalProcess L-cysteine catabolic process The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid. go-plus.json L-cysteine catabolism|L-cysteine degradation|L-cysteine breakdown http://purl.obolibrary.org/obo/GO_0019448 GO:0044459 biolink:CellularComponent obsolete plasma membrane part OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0044459 gocheck_do_not_annotate GO:0019445 biolink:BiologicalProcess tyrosine catabolic process to fumarate The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate. MetaCyc:TYRFUMCAT-PWY go-plus.json tyrosine degradation to fumarate|tyrosine breakdown to fumarate http://purl.obolibrary.org/obo/GO_0019445 GO:0019446 biolink:BiologicalProcess obsolete tyrosine catabolic process to phosphoenolpyruvate OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate. go-plus.json tyrosine breakdown to phosphoenolpyruvate|tyrosine degradation to phosphoenolpyruvate http://purl.obolibrary.org/obo/GO_0019446 GO:0019443 biolink:BiologicalProcess obsolete tryptophan catabolic process, using tryptophanase OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tryptophan, catalyzed by the enzyme tryptophanase (EC:4.1.99.1). go-plus.json tryptophan catabolic process, using tryptophanase|tryptophan breakdown, using tryptophanase|tryptophan degradation, using tryptophanase http://purl.obolibrary.org/obo/GO_0019443 GO:0019444 biolink:BiologicalProcess tryptophan catabolic process to catechol The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol. MetaCyc:TRPCAT-PWY go-plus.json tryptophan breakdown to catechol|tryptophan degradation to catechol http://purl.obolibrary.org/obo/GO_0019444 GO:0019441 biolink:BiologicalProcess tryptophan catabolic process to kynurenine The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine. MetaCyc:TRPKYNCAT-PWY go-plus.json tryptophan degradation to kynurenine|tryptophan breakdown to kynurenine http://purl.obolibrary.org/obo/GO_0019441 GO:0019442 biolink:BiologicalProcess tryptophan catabolic process to acetyl-CoA The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA. MetaCyc:TRYPTOPHAN-DEGRADATION-1 go-plus.json tryptophan degradation to acetyl-CoA|tryptophan breakdown to acetyl-CoA http://purl.obolibrary.org/obo/GO_0019442 GO:0019440 biolink:BiologicalProcess tryptophan catabolic process to indole-3-acetate The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate. MetaCyc:TRPIAACAT-PWY go-plus.json tryptophan catabolism to indoleacetic acid|tryptophan degradation to indole-3-acetate|tryptophan breakdown to indole-3-acetate|tryptophan catabolic process to indoleacetic acid|tryptophan catabolic process to IAA http://purl.obolibrary.org/obo/GO_0019440 GO:0044460 biolink:CellularComponent obsolete flagellum part OBSOLETE. Any constituent part of a flagellum, a long whiplike or feathery structure borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium. go-plus.json flagellum part|flagellum component http://purl.obolibrary.org/obo/GO_0044460 GO:0044467 biolink:BiologicalProcess glial cell-derived neurotrophic factor production The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons. go-plus.json glial cell-derived neurotrophic factor secretion|GDNF production|glial cell line-derived neurotrophic factor production http://purl.obolibrary.org/obo/GO_0044467 gocheck_do_not_annotate GO:0044468 biolink:BiologicalProcess envenomation resulting in modulation of blood coagulation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism. go-plus.json envenomation resulting in regulation of blood coagulation in other organism http://purl.obolibrary.org/obo/GO_0044468 GO:0044465 biolink:BiologicalProcess modulation of sensory perception of pain in other organism A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism. go-plus.json regulation of sensory perception of pain in another organism http://purl.obolibrary.org/obo/GO_0044465 GO:0044466 biolink:MolecularActivity glutaryl-CoA hydrolase activity Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate. EC:3.1.2.3 go-plus.json glutaryl-CoA thioesterase activity http://purl.obolibrary.org/obo/GO_0044466 CHEBI:140750 biolink:ChemicalSubstance D-5-phenylhydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140750 chebi_ph7_3 GO:0044463 biolink:CellularComponent obsolete cell projection part OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon. go-plus.json http://purl.obolibrary.org/obo/GO_0044463 gocheck_do_not_annotate GO:0044464 biolink:CellularComponent obsolete cell part OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms. NIF_Subcellular:sao628508602 go-plus.json cellular subcomponent|protoplast http://purl.obolibrary.org/obo/GO_0044464 gocheck_do_not_annotate|goslim_pir GO:0044461 biolink:CellularComponent obsolete bacterial-type flagellum part OBSOLETE. Any constituent part of the bacterial-type flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by a transmembrane ion potential, typically a proton or sodium potential. go-plus.json flagellin-based flagellum part http://purl.obolibrary.org/obo/GO_0044461 gocheck_do_not_annotate CHEBI:43088 biolink:ChemicalSubstance N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_43088 GO:0044462 biolink:CellularComponent obsolete external encapsulating structure part OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria). go-plus.json http://purl.obolibrary.org/obo/GO_0044462 gocheck_do_not_annotate GO:0019418 biolink:BiologicalProcess sulfide oxidation The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate. MetaCyc:P222-PWY go-plus.json sulphide oxidation http://purl.obolibrary.org/obo/GO_0019418 GO:0019419 biolink:BiologicalProcess sulfate reduction The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate. go-plus.json sulphate reduction|sulphate reduction, APS pathway|sulfate reduction, APS pathway|assimilatory sulphate reduction|assimilatory sulfate reduction http://purl.obolibrary.org/obo/GO_0019419 CHEBI:140758 biolink:ChemicalSubstance N-carbamoyl-D-phenylglycine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140758 chebi_ph7_3 GO:0019416 biolink:BiologicalProcess polythionate oxidation The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor. MetaCyc:THIOSULFOX-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019416 GO:0019417 biolink:BiologicalProcess sulfur oxidation The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur. go-plus.json sulphur oxidation http://purl.obolibrary.org/obo/GO_0019417 GO:0044469 biolink:BiologicalProcess envenomation resulting in positive regulation of blood coagulation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044469 GO:0019414 biolink:BiologicalProcess aerobic respiration, using sulfur or sulfate as electron donor An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized. go-plus.json aerobic respiration, using sulphur or sulphate as electron donor http://purl.obolibrary.org/obo/GO_0019414 GO:0019415 biolink:BiologicalProcess acetate biosynthetic process from carbon monoxide The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide. go-plus.json acetate formation from carbon monoxide|acetate synthesis from carbon monoxide|acetate anabolism from carbon monoxide|carbon monoxide dehydrogenase pathway http://purl.obolibrary.org/obo/GO_0019415 GO:0019412 biolink:BiologicalProcess aerobic respiration, using hydrogen as electron donor The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water. MetaCyc:P283-PWY go-plus.json hydrogen oxidation http://purl.obolibrary.org/obo/GO_0019412 GO:0019413 biolink:BiologicalProcess acetate biosynthetic process The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid. go-plus.json acetate anabolism|acetate synthesis|acetate formation|acetate biosynthesis http://purl.obolibrary.org/obo/GO_0019413 GO:0019410 biolink:BiologicalProcess aerobic respiration, using carbon monoxide as electron donor The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation. go-plus.json http://purl.obolibrary.org/obo/GO_0019410 GO:0019411 biolink:BiologicalProcess aerobic respiration, using ferrous ions as electron donor The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide. go-plus.json http://purl.obolibrary.org/obo/GO_0019411 GO:0044470 biolink:BiologicalProcess envenomation resulting in negative regulation of blood coagulation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044470 CHEBI:43074 biolink:ChemicalSubstance (3S)-3-hydroxy-3-methylglutaryl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_43074 chebi_ph7_3 GO:0044471 biolink:BiologicalProcess envenomation resulting in pore formation in membrane of other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044471 GO:0044478 biolink:BiologicalProcess envenomation resulting in positive regulation of platelet aggregation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044478 CHEBI:140741 biolink:ChemicalSubstance hypotaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140741 GO:0044479 biolink:BiologicalProcess envenomation resulting in modulation of mast cell degranulation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044479 GO:0044476 biolink:BiologicalProcess envenomation resulting in negative regulation of low voltage-gated calcium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044476 GO:0044477 biolink:BiologicalProcess envenomation resulting in negative regulation of platelet aggregation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044477 GO:0044474 biolink:BiologicalProcess envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044474 GO:0044475 biolink:BiologicalProcess envenomation resulting in negative regulation of high voltage-gated calcium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044475 GO:0044472 biolink:BiologicalProcess envenomation resulting in modulation of calcium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044472 GO:0044473 biolink:BiologicalProcess envenomation resulting in negative regulation of calcium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044473 GO:0019429 biolink:BiologicalProcess fluorene catabolic process The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents. UM-BBD_pathwayID:flu|MetaCyc:FLUORENE-DEG-9-ONE-PWY go-plus.json fluorene metabolic process|fluorene degradation|fluorene breakdown|fluorene catabolism|fluorene metabolism http://purl.obolibrary.org/obo/GO_0019429 GO:0019427 biolink:BiologicalProcess acetyl-CoA biosynthetic process from acetate The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate. MetaCyc:ACETATEUTIL-PWY go-plus.json acetyl-CoA formation from acetate|acetyl-CoA synthesis from acetate|acetyl-CoA anabolism from acetate|acetate utilization http://purl.obolibrary.org/obo/GO_0019427 GO:0019428 biolink:BiologicalProcess allantoin biosynthetic process The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. MetaCyc:URSIN-PWY go-plus.json allantoin anabolism|allantoin synthesis|allantoin formation|allantoin biosynthesis http://purl.obolibrary.org/obo/GO_0019428 GO:0019425 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019425 GO:0019426 biolink:BiologicalProcess bisulfite reduction The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite. MetaCyc:P224-PWY go-plus.json bisulphite reduction http://purl.obolibrary.org/obo/GO_0019426 CHEBI:140743 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_140743 chebi_ph7_3 GO:0019423 biolink:BiologicalProcess sulfur oxidation, ferric ion-dependent A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+). MetaCyc:FESULFOX-PWY go-plus.json sulphur oxidation, ferric ion-dependent http://purl.obolibrary.org/obo/GO_0019423 GO:0019424 biolink:BiologicalProcess sulfide oxidation, using siroheme sulfite reductase A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase. MetaCyc:P223-PWY go-plus.json sulphur oxidation, using siroheme sulphite reductase|sulfur oxidation, using sirohaem sulfite reductase|sulphide oxidation, using siroheme sulphite reductase|sulfide oxidation, using sirohaem sulfite reductase|sulfur oxidation, using siroheme sulfite reductase http://purl.obolibrary.org/obo/GO_0019424 GO:0019421 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019421 GO:0019422 biolink:BiologicalProcess disproportionation of elemental sulfur The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2. MetaCyc:P203-PWY go-plus.json disproportionation of elemental sulphur http://purl.obolibrary.org/obo/GO_0019422 GO:0019420 biolink:BiologicalProcess dissimilatory sulfate reduction The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide. MetaCyc:DISSULFRED-PWY go-plus.json dissimilatory sulphate reduction http://purl.obolibrary.org/obo/GO_0019420 GO:0044481 biolink:BiologicalProcess envenomation resulting in proteolysis in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant hydrolysis of proteins in of the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044481 GO:0044482 biolink:BiologicalProcess envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism. go-plus.json envenomation resulting in blood vessel ECM, causing hemorrhagic damage in other organism http://purl.obolibrary.org/obo/GO_0044482 GO:0044480 biolink:BiologicalProcess envenomation resulting in positive regulation of mast cell degranulation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044480 GO:0044489 biolink:BiologicalProcess negative regulation of voltage-gated sodium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044489 GO:0044487 biolink:BiologicalProcess envenomation resulting in modulation of transmission of nerve impulse in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism. go-plus.json envenomation resulting in modulation of conduction of nerve impulse in other organism http://purl.obolibrary.org/obo/GO_0044487 GO:0044488 biolink:BiologicalProcess modulation of voltage-gated sodium channel activity in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044488 GO:0044485 biolink:BiologicalProcess envenomation resulting in fibrinogenolysis in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044485 GO:0044486 biolink:BiologicalProcess modulation of transmission of nerve impulse in other organism The process in which an organism effects a change in the transmission of a nerve impulse in another organism. go-plus.json modulation of conduction of nerve impulse in other organism|regulation of transmission of nerve impulse in other organism http://purl.obolibrary.org/obo/GO_0044486 CHEBI:43065 biolink:ChemicalSubstance (S)-3-phenyllactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43065 GO:0044483 biolink:BiologicalProcess envenomation resulting in impairment of hemostasis in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism. go-plus.json envenomation resulting in negative regulation of hemostasis in other organism|envenomation, impairing hemostasis in other organism http://purl.obolibrary.org/obo/GO_0044483 GO:0044484 biolink:BiologicalProcess envenomation resulting in fibrinolysis in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044484 GO:0044492 biolink:BiologicalProcess envenomation resulting in modulation of voltage-gated sodium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044492 GO:0044493 biolink:BiologicalProcess envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044493 GO:0044490 biolink:BiologicalProcess positive regulation of voltage-gated sodium channel activity in other organism Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044490 GO:0044491 biolink:BiologicalProcess positive regulation of molecular function in other organism Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044491 GO:0044498 biolink:BiologicalProcess envenomation resulting in modulation of blood pressure in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism. go-plus.json envenomation resulting in regulation of blood pressure in other organism http://purl.obolibrary.org/obo/GO_0044498 GO:0044499 biolink:BiologicalProcess envenomation resulting in positive regulation of blood pressure in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044499 CHEBI:43056 biolink:ChemicalSubstance L-gamma-glutamyl-S-nitroso-D-cysteinylglycine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_43056 chebi_ph7_3 GO:0044496 biolink:BiologicalProcess negative regulation of blood pressure in other organism A process by which one organism decreases the force with which blood travels through the circulatory system of another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044496 GO:0044497 biolink:BiologicalProcess positive regulation of blood pressure in other organism A process by which one organism increases the force with which blood travels through the circulatory system of another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044497 GO:0044494 biolink:BiologicalProcess envenomation resulting in positive regulation of voltage-gated sodium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044494 GO:0044495 biolink:BiologicalProcess modulation of blood pressure in other organism A process by which one organism modulates the force with which blood travels through the circulatory system of another organism. go-plus.json regulation of blood pressure in other organism http://purl.obolibrary.org/obo/GO_0044495 CHEBI:57693 biolink:ChemicalSubstance aldehydo-D-arabinose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57693 chebi_ph7_3 GO:0019409 biolink:BiologicalProcess aerobic respiration, using ammonia as electron donor The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite. MetaCyc:AMMOXID-PWY go-plus.json aerobic ammonia oxidation to nitrite via hydrazine http://purl.obolibrary.org/obo/GO_0019409 CHEBI:57694 biolink:ChemicalSubstance quercetin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57694 chebi_ph7_3 GO:0019407 biolink:BiologicalProcess hexitol catabolic process The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule. go-plus.json hexitol catabolism|hexitol degradation|hexitol breakdown http://purl.obolibrary.org/obo/GO_0019407 CHEBI:57691 biolink:ChemicalSubstance N(6)-acyl-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57691 chebi_ph7_3 GO:0019408 biolink:BiologicalProcess dolichol biosynthetic process The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units. go-plus.json dolichol anabolism|dolichol biosynthesis|dolichol synthesis|dolichol formation http://purl.obolibrary.org/obo/GO_0019408 CHEBI:57692 biolink:ChemicalSubstance FAD(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57692 chebi_ph7_3 CHEBI:140725 biolink:ChemicalSubstance 4-Imidazolone-5-propanoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140725 GO:0019405 biolink:BiologicalProcess alditol catabolic process The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. go-plus.json alditol catabolism|alditol degradation|alditol breakdown http://purl.obolibrary.org/obo/GO_0019405 GO:0019406 biolink:BiologicalProcess hexitol biosynthetic process The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule. go-plus.json hexitol formation|hexitol biosynthesis|hexitol anabolism|hexitol synthesis http://purl.obolibrary.org/obo/GO_0019406 CHEBI:57690 biolink:ChemicalSubstance cis-4-hydroxy-D-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57690 chebi_ph7_3 GO:0019403 biolink:BiologicalProcess galactitol biosynthetic process The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. go-plus.json galactitol biosynthesis|galactitol anabolism|galactitol synthesis|galactitol formation http://purl.obolibrary.org/obo/GO_0019403 GO:0019404 biolink:BiologicalProcess galactitol catabolic process The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. MetaCyc:GALACTITOLCAT-PWY go-plus.json galactitol degradation|galactitol breakdown|galactitol catabolism http://purl.obolibrary.org/obo/GO_0019404 GO:0019401 biolink:BiologicalProcess alditol biosynthetic process The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. go-plus.json alditol formation|alditol biosynthesis|alditol anabolism|alditol synthesis http://purl.obolibrary.org/obo/GO_0019401 GO:0019402 biolink:BiologicalProcess galactitol metabolic process The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. go-plus.json galactitol metabolism http://purl.obolibrary.org/obo/GO_0019402 CHEBI:57699 biolink:ChemicalSubstance L-histidinol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57699 chebi_ph7_3 GO:0019400 biolink:BiologicalProcess alditol metabolic process The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. go-plus.json alditol metabolism http://purl.obolibrary.org/obo/GO_0019400 CHEBI:57697 biolink:ChemicalSubstance deaminohydroxyblasticidin S(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57697 chebi_ph7_3 CHEBI:57698 biolink:ChemicalSubstance 2-(acetamidomethylidene)succinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57698 chebi_ph7_3 CHEBI:57695 biolink:ChemicalSubstance D-ribitol 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57695 chebi_ph7_3 CHEBI:67010 biolink:ChemicalSubstance L-kynureninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67010 CHEBI:67011 biolink:ChemicalSubstance folates go-plus.json http://purl.obolibrary.org/obo/CHEBI_67011 CHEBI:67016 biolink:ChemicalSubstance tetrahydrofolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67016 CHEBI:67012 biolink:ChemicalSubstance L-dopa(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67012 CHEBI:82643 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82643 chebi_ph7_3 CHEBI:67013 biolink:ChemicalSubstance methyl-branched fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_67013 CHEBI:67014 biolink:ChemicalSubstance dihydrofolates go-plus.json http://purl.obolibrary.org/obo/CHEBI_67014 CHEBI:67015 biolink:ChemicalSubstance N(omega)-methyl-L-argininate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67015 CHEBI:67021 biolink:ChemicalSubstance N-docosanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67021 chebi_ph7_3 CHEBI:67022 biolink:ChemicalSubstance lipoxin anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_67022 CHEBI:67027 biolink:ChemicalSubstance N-eicosanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67027 chebi_ph7_3 CHEBI:82657 biolink:ChemicalSubstance deoxyhypusine(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82657 chebi_ph7_3 CHEBI:67023 biolink:ChemicalSubstance N-(2-hydroxydocosanoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67023 chebi_ph7_3 CHEBI:67026 biolink:ChemicalSubstance lipoxin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67026 chebi_ph7_3 CHEBI:67031 biolink:ChemicalSubstance lipoxin B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67031 chebi_ph7_3 CHEBI:67032 biolink:ChemicalSubstance O-phosphonatooxyserine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67032 chebi_ph7_3 CHEBI:67033 biolink:ChemicalSubstance N-octodecanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67033 chebi_ph7_3 CHEBI:67039 biolink:ChemicalSubstance prenylcysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67039 CHEBI:67034 biolink:ChemicalSubstance N-(2-hydroxyoctadecanoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67034 chebi_ph7_3 CHEBI:67035 biolink:ChemicalSubstance N-octadecanoyl-4-hydroxysphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67035 chebi_ph7_3 CHEBI:67036 biolink:ChemicalSubstance O-(N-acetylglucosamine-1-phosphonatooxy)-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67036 chebi_ph7_3 CHEBI:82663 biolink:ChemicalSubstance elemental iron go-plus.json http://purl.obolibrary.org/obo/CHEBI_82663 CHEBI:67037 biolink:ChemicalSubstance D-octopine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67037 CHEBI:67042 biolink:ChemicalSubstance N-hexadecanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67042 chebi_ph7_3 CHEBI:67043 biolink:ChemicalSubstance N-(2-hydroxyhexadecanoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67043 chebi_ph7_3 CHEBI:67040 biolink:ChemicalSubstance S-adenosyl-L-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67040 CHEBI:82679 biolink:ChemicalSubstance 7-oxolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82679 CHEBI:67049 biolink:ChemicalSubstance N(alpha),N(alpha),N(alpha)-trimethyl-L-histidinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67049 CHEBI:82678 biolink:ChemicalSubstance 3beta-hydroxy-7-oxo-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82678 CHEBI:67045 biolink:ChemicalSubstance N-tetradecanoylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67045 chebi_ph7_3 PR:000008725 biolink:Protein haptoglobin A protein that is a translation product of the human HP gene or a 1:1 ortholog thereof. go-plus.json HP http://purl.obolibrary.org/obo/PR_000008725 CHEBI:67052 biolink:ChemicalSubstance glyphosate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67052 CHEBI:67050 biolink:ChemicalSubstance S-methyl-L-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67050 CHEBI:67051 biolink:ChemicalSubstance phosphopantetheine anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_67051 CHEBI:82687 biolink:ChemicalSubstance 5-(2-hydroxyethyl)-1,3-thiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_82687 chebi_ph7_3 CHEBI:67058 biolink:ChemicalSubstance lysophosphatidylcholine 20:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_67058 chebi_ph7_3 CHEBI:82684 biolink:ChemicalSubstance 7-O-methylvitexin 2''-O-beta-L-rhamnoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_82684 CHEBI:82685 biolink:ChemicalSubstance Mo(=O)(=S)-molybdopterin cofactor(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82685 chebi_ph7_3 CHEBI:82682 biolink:ChemicalSubstance vitexin 2''-O-beta-L-rhamnoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_82682 CHEBI:82683 biolink:ChemicalSubstance O-[2'-(5-phosphoribosyl)-3'-dephospho-CoA]-L-serine(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82683 chebi_ph7_3 CHEBI:82680 biolink:ChemicalSubstance monounsaturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_82680 chebi_ph7_3 CHEBI:82681 biolink:ChemicalSubstance 3-methoxy-5-methyl-1-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82681 GO:0019498 biolink:BiologicalProcess n-octane oxidation The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA. MetaCyc:P221-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019498 GO:0019499 biolink:BiologicalProcess cyanide metabolic process The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain. go-plus.json cyanide metabolism http://purl.obolibrary.org/obo/GO_0019499 GO:0019496 biolink:BiologicalProcess serine-isocitrate lyase pathway A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide. go-plus.json http://purl.obolibrary.org/obo/GO_0019496 GO:0019497 biolink:BiologicalProcess hexachlorocyclohexane metabolic process The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution. go-plus.json hexachlorocyclohexane metabolism http://purl.obolibrary.org/obo/GO_0019497 GO:0019494 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019494 GO:0019495 biolink:BiologicalProcess proline catabolic process to 2-oxoglutarate The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate. go-plus.json proline catabolic process to 2-ketoglutarate|proline catabolic process to alpha-oxoglutarate|proline catabolism to alpha-ketoglutarate|proline degradation to 2-oxoglutarate|proline catabolism to 2-ketoglutarate|proline breakdown to 2-oxoglutarate|proline catabolism to alpha-oxoglutarate|proline catabolic process to alpha-ketoglutarate http://purl.obolibrary.org/obo/GO_0019495 CHEBI:67063 biolink:ChemicalSubstance poly-beta-1,6-N-acetyl-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67063 CHEBI:67064 biolink:ChemicalSubstance phosphatidylcholine O-36:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_67064 chebi_ph7_3 CHEBI:67062 biolink:ChemicalSubstance lipo-chitin oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_67062 CHEBI:82697 biolink:ChemicalSubstance N-(ADP-D-ribosyl)diphthamide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82697 chebi_ph7_3 CHEBI:82695 biolink:ChemicalSubstance 2-[(3S)-3-carboxylato-3-(dimethylammonio)propyl]-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82695 chebi_ph7_3 CHEBI:82696 biolink:ChemicalSubstance diphthine betaine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82696 chebi_ph7_3 CHEBI:82693 biolink:ChemicalSubstance 2-[(3S)-3-carboxylato-3-(methylammonio)propyl]-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82693 chebi_ph7_3 GO:0019481 biolink:BiologicalProcess L-alanine catabolic process, by transamination The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination. MetaCyc:ALANINE-DEG3-PWY go-plus.json L-alanine degradation, by transamination|L-alanine breakdown, by transamination http://purl.obolibrary.org/obo/GO_0019481 GO:0019482 biolink:BiologicalProcess beta-alanine metabolic process The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. Wikipedia:Beta-alanine go-plus.json beta-alanine metabolism http://purl.obolibrary.org/obo/GO_0019482 GO:0019480 biolink:BiologicalProcess L-alanine oxidation to pyruvate via D-alanine The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate. MetaCyc:ALADEG-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019480 CHEBI:67072 biolink:ChemicalSubstance cannabinoid receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_67072 GO:0044401 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044401 GO:0044402 biolink:BiologicalProcess obsolete competition with other organism OBSOLETE. Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community. go-plus.json competition with another organism|interspecies competition http://purl.obolibrary.org/obo/GO_0044402 GO:0044400 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044400 CHEBI:67078 biolink:ChemicalSubstance Delta(9)-tetrahydrocannabinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67078 CHEBI:67079 biolink:ChemicalSubstance anti-inflammatory agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_67079 GO:0044409 biolink:BiologicalProcess entry into host Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json entry into host cell via penetration peg|penetration into host via a specialized structure during symbiotic interaction|entry into cell of other organism involved in symbiotic interaction|invasion of host|penetration into host via a specialized structure|host cell invasion|entry into host through host barriers|entry into host cell|invasion into host|invasive growth|entry into other organism during symbiotic interaction|entry into other organism involved in symbiotic interaction|entry into host via enzymatic degradation of host cuticle|entry into host via enzymatic degradation of host anatomical structure|entry into cell of other organism during symbiotic interaction|other organism cell invasion|invasion of other organism|penetration into host|host penetration|invasion into other organism|entry into host via a specialized structure during symbiotic interaction|other organism invasion|host invasion http://purl.obolibrary.org/obo/GO_0044409 GO:0044407 biolink:BiologicalProcess single-species biofilm formation in or on host organism A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044407 GO:0044408 biolink:BiologicalProcess obsolete growth or development of symbiont on or near host OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. go-plus.json growth or development of symbiont on or near host|growth or development of organism on or near host surface http://purl.obolibrary.org/obo/GO_0044408 GO:0044405 biolink:BiologicalProcess detection of host The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json recognition of host http://purl.obolibrary.org/obo/GO_0044405 GO:0044406 biolink:BiologicalProcess adhesion of symbiont to host The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adhesion to other organism involved in symbiotic interaction|adhesion to other organism during symbiotic interaction|host adhesion|adhesion to host|adhesion to symbiont http://purl.obolibrary.org/obo/GO_0044406 GO:0044403 biolink:BiologicalProcess biological process involved in symbiotic interaction A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts. go-plus.json symbiosis|symbiotic process|symbiotic interaction between host and organism|parasitism|symbiosis, encompassing mutualism through parasitism|symbiotic interaction between organisms|host-pathogen interaction|commensalism|symbiotic interaction between species|symbiotic interaction http://purl.obolibrary.org/obo/GO_0044403 goslim_chembl|goslim_generic GO:0044404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044404 GO:0019478 biolink:BiologicalProcess D-amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids. go-plus.json D-amino acid degradation|D-amino acid breakdown|D-amino acid catabolism http://purl.obolibrary.org/obo/GO_0019478 GO:0019479 biolink:BiologicalProcess L-alanine oxidation to D-lactate and ammonia The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia. MetaCyc:ALACAT2-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019479 GO:0019476 biolink:BiologicalProcess D-lysine catabolic process The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid. go-plus.json D-lysine catabolism|D-lysine degradation|D-lysine breakdown http://purl.obolibrary.org/obo/GO_0019476 GO:0019477 biolink:BiologicalProcess L-lysine catabolic process The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid. go-plus.json L-lysine catabolism|L-lysine degradation|L-lysine breakdown http://purl.obolibrary.org/obo/GO_0019477 CHEBI:67080 biolink:ChemicalSubstance cannabinerolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67080 GO:0019474 biolink:BiologicalProcess L-lysine catabolic process to acetyl-CoA The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA. go-plus.json L-lysine degradation to acetyl-CoA|L-lysine breakdown to acetyl-CoA http://purl.obolibrary.org/obo/GO_0019474 GO:0019475 biolink:BiologicalProcess L-lysine catabolic process to acetate The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate. MetaCyc:P163-PWY go-plus.json lysine fermentation|L-lysine breakdown to acetate|L-lysine degradation to acetate http://purl.obolibrary.org/obo/GO_0019475 GO:0019472 biolink:BiologicalProcess 4-hydroxyproline biosynthetic process The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. go-plus.json 4-hydroxyproline biosynthesis|4-hydroxyproline anabolism|4-hydroxyproline synthesis|4-hydroxyproline formation http://purl.obolibrary.org/obo/GO_0019472 GO:0019473 biolink:BiologicalProcess L-lysine catabolic process to glutarate, by acetylation The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation. MetaCyc:LYSDEGII-PWY go-plus.json L-lysine degradation to glutarate, by acetylation|L-lysine breakdown to glutarate, by acetylation http://purl.obolibrary.org/obo/GO_0019473 GO:0019492 biolink:BiologicalProcess proline salvage Any process which produces the amino acid proline from derivatives of it, without de novo synthesis. go-plus.json proline cycling http://purl.obolibrary.org/obo/GO_0019492 GO:0019493 biolink:BiologicalProcess arginine catabolic process to proline The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline. MetaCyc:ARG-PRO-PWY go-plus.json arginine degradation to proline|arginine breakdown to proline http://purl.obolibrary.org/obo/GO_0019493 GO:0019490 biolink:BiologicalProcess 2-aminobenzenesulfonate desulfonation The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. MetaCyc:2ASDEG-PWY go-plus.json 2-aminobenzenesulphonate desulphonation http://purl.obolibrary.org/obo/GO_0019490 GO:0019491 biolink:BiologicalProcess ectoine biosynthetic process The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. MetaCyc:P101-PWY go-plus.json ectoine biosynthesis|ectoine anabolism|ectoine synthesis|ectoine formation http://purl.obolibrary.org/obo/GO_0019491 CHEBI:67081 biolink:ChemicalSubstance cannabigerolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67081 GO:0044412 biolink:BiologicalProcess obsolete growth or development of symbiont in host OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont within host|growth or development of organism within host|growth or development of symbiont in host|invasive growth http://purl.obolibrary.org/obo/GO_0044412 GO:0044413 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044413 GO:0044410 biolink:BiologicalProcess entry into host through natural portals Penetration by a symbiont into a host organism via naturally occurring openings in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json entry into other organism through natural portals involved in symbiotic interaction|entry into other organism through natural portals during symbiotic interaction http://purl.obolibrary.org/obo/GO_0044410 GO:0044411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044411 CHEBI:67089 biolink:ChemicalSubstance 3,5,7-trioxododecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_67089 GO:0044418 biolink:BiologicalProcess translocation of DNA into host The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json translocation of DNA into other organism during symbiotic interaction|translocation of DNA into other organism involved in symbiotic interaction|transport of DNA into other organism during symbiotic interaction|transport of DNA into host http://purl.obolibrary.org/obo/GO_0044418 GO:0044419 biolink:BiologicalProcess biological process involved in interspecies interaction between organisms Any process evolved to enable an interaction with an organism of a different species. go-plus.json interspecies interaction with other organisms|interspecies interaction between organisms|interaction with another species|interspecies interaction http://purl.obolibrary.org/obo/GO_0044419 gocheck_do_not_annotate|goslim_pir|goslim_candida GO:0044416 biolink:BiologicalProcess induction by symbiont of host defense response The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of defense response of other organism involved in symbiotic interaction|stimulation by symbiont of host defense response|up-regulation by symbiont of host defense response|activation of host defense response|upregulation by symbiont of host defense response|positive regulation by organism of defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host defense response|positive regulation by symbiont of host defense response|activation by symbiont of host defense response http://purl.obolibrary.org/obo/GO_0044416 GO:0044417 biolink:BiologicalProcess translocation of molecules into host The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json transport of molecules into host|translocation of molecules into other organism during symbiotic interaction|translocation of molecules into other organism involved in symbiotic interaction|transport of molecules into other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0044417 GO:0044414 biolink:BiologicalProcess suppression of host defenses by symbiont Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json inhibition by symbiont of host defense response|down regulation by organism of defense response of other organism during symbiotic interaction|negative regulation by organism of defense response of other organism involved in symbiotic interaction|suppression of defense response of other organism involved in symbiotic interaction|downregulation by organism of defense response of other organism during symbiotic interaction|suppression of host defense response|down regulation by symbiont of host defense response|down-regulation by organism of defense response of other organism during symbiotic interaction|inhibition by organism of defense response of other organism during symbiotic interaction|downregulation by symbiont of host defense response|negative regulation of host defenses|suppression of defenses of other organism involved in symbiotic interaction|negative regulation by organism of defense response of other organism during symbiotic interaction|down-regulation by symbiont of host defense response|negative regulation by symbiont of host defense response|suppression of defense response of other organism http://purl.obolibrary.org/obo/GO_0044414 GO:0044415 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044415 GO:0019489 biolink:BiologicalProcess methylgallate metabolic process The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid. go-plus.json methylgallate metabolism http://purl.obolibrary.org/obo/GO_0019489 GO:0019487 biolink:BiologicalProcess anaerobic acetylene catabolic process The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen. MetaCyc:P161-PWY go-plus.json anaerobic ethyne catabolism|anaerobic ethyne catabolic process|anaerobic acetylene degradation|anaerobic acetylene catabolism|anaerobic acetylene breakdown http://purl.obolibrary.org/obo/GO_0019487 CHEBI:67090 biolink:ChemicalSubstance N-acylsphinganine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67090 chebi_ph7_3 GO:0019488 biolink:BiologicalProcess ribitol catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate. MetaCyc:RIBITOLUTIL-PWY go-plus.json ribitol degradation to xylulose 5-phosphate|ribitol breakdown to xylulose 5-phosphate|ribitol utilization http://purl.obolibrary.org/obo/GO_0019488 GO:0019485 biolink:BiologicalProcess beta-alanine catabolic process to L-alanine The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine. go-plus.json beta-alanine breakdown to L-alanine|beta-alanine degradation to L-alanine http://purl.obolibrary.org/obo/GO_0019485 GO:0019486 biolink:BiologicalProcess beta-alanine catabolic process to mevalonate semialdehyde, by transamination The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination. MetaCyc:BETA-ALA-DEGRADATION-I-PWY go-plus.json beta-alanine degradation to mevalonate semialdehyde, by transamination|beta-alanine breakdown to mevalonate semialdehyde, by transamination http://purl.obolibrary.org/obo/GO_0019486 GO:0019483 biolink:BiologicalProcess beta-alanine biosynthetic process The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. go-plus.json beta-alanine anabolism|beta-alanine biosynthesis|beta-alanine synthesis|beta-alanine formation http://purl.obolibrary.org/obo/GO_0019483 GO:0019484 biolink:BiologicalProcess beta-alanine catabolic process The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. go-plus.json beta-alanine catabolism|beta-alanine degradation|beta-alanine breakdown http://purl.obolibrary.org/obo/GO_0019484 CHEBI:57608 biolink:ChemicalSubstance CDP-ribitol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57608 chebi_ph7_3 CHEBI:57609 biolink:ChemicalSubstance (2S,6S)-2,6-diaminopimelic acid dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57609 chebi_ph7_3 CHEBI:57606 biolink:ChemicalSubstance 5-oxoprolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57606 chebi_ph7_3 CHEBI:57607 biolink:ChemicalSubstance oleandomycin 2'-O-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57607 chebi_ph7_3 CHEBI:57604 biolink:ChemicalSubstance 3-phosphonato-D-glyceroyl phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57604 chebi_ph7_3 CHEBI:57605 biolink:ChemicalSubstance adenin-9-yl riburonosate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57605 chebi_ph7_3 CHEBI:33635 biolink:ChemicalSubstance polycyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33635 CHEBI:33636 biolink:ChemicalSubstance bicyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33636 CHEBI:33637 biolink:ChemicalSubstance ortho-fused compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33637 CHEBI:33639 biolink:ChemicalSubstance ortho- and peri-fused compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33639 CHEBI:57602 biolink:ChemicalSubstance (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57602 chebi_ph7_3 CHEBI:57603 biolink:ChemicalSubstance ethanolaminium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57603 chebi_ph7_3 CHEBI:57600 biolink:ChemicalSubstance GTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57600 CHEBI:57601 biolink:ChemicalSubstance 2-methylpropanaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57601 chebi_ph7_3 CHEBI:33646 biolink:ChemicalSubstance alkadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33646 CHEBI:33647 biolink:ChemicalSubstance alkatriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33647 UBERON:0004495 biolink:AnatomicalEntity skeletal muscle tissue of diaphragm A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004495 UBERON:0004493 biolink:AnatomicalEntity cardiac muscle tissue of myocardium A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004493 CHEBI:33641 biolink:ChemicalSubstance olefin go-plus.json http://purl.obolibrary.org/obo/CHEBI_33641 UBERON:0004491 biolink:AnatomicalEntity cardiac muscle tissue of interatrial septum A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]. go-plus.json interatrial septum muscle|interatrial septum myocardium|interatrial septum heart muscle|interatrial septum cardiac muscle tissue http://purl.obolibrary.org/obo/UBERON_0004491 CHEBI:33642 biolink:ChemicalSubstance cyclic olefin go-plus.json http://purl.obolibrary.org/obo/CHEBI_33642 UBERON:0004492 biolink:AnatomicalEntity cardiac muscle tissue of cardiac septum A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]. go-plus.json cardiac septum cardiac muscle tissue|cardiac septum muscle|cardiac septum myocardium|cardiac septum heart muscle http://purl.obolibrary.org/obo/UBERON_0004492 CHEBI:33643 biolink:ChemicalSubstance cycloalkene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33643 CHEBI:33644 biolink:ChemicalSubstance acetylenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_33644 CHEBI:33645 biolink:ChemicalSubstance acyclic olefin go-plus.json http://purl.obolibrary.org/obo/CHEBI_33645 UBERON:0004490 biolink:AnatomicalEntity cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]. go-plus.json atrial cardiac muscle tissue|atrial heart muscle|atrial myocardium|cardiac atrium muscle http://purl.obolibrary.org/obo/UBERON_0004490 CHEBI:18020 biolink:ChemicalSubstance 4-trimethylammoniobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_18020 chebi_ph7_3 NCBITaxon:2691354 biolink:OrganismalEntity Pirellulales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2691354 CHEBI:33613 biolink:ChemicalSubstance 2,2-bis(4-hydroxyphenyl)propan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33613 chebi_ph7_3 NCBITaxon:2691357 biolink:OrganismalEntity Pirellulaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2691357 CHEBI:33619 biolink:ChemicalSubstance boron oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33619 UBERON:0004482 biolink:AnatomicalEntity musculature of lower limb Any collection of muscles that is part of a hindlimb [Automatically generated definition]. go-plus.json musculature of free lower limb|muscle group of free lower limb|free lower limb musculature|set of muscles of free lower limb http://purl.obolibrary.org/obo/UBERON_0004482 UBERON:0004480 biolink:AnatomicalEntity musculature of limb Any collection of muscles that is part of a limb [Automatically generated definition]. go-plus.json limb musculature|set of muscles of limb|limb muscle system|muscle group of limb http://purl.obolibrary.org/obo/UBERON_0004480 UBERON:0004481 biolink:AnatomicalEntity musculature of upper limb Any collection of muscles that is part of a forelimb [Automatically generated definition]. go-plus.json musculature of free upper limb|muscle group of free upper limb|free upper limb musculature|set of muscles of free upper limb http://purl.obolibrary.org/obo/UBERON_0004481 CHEBI:33610 biolink:ChemicalSubstance monoatomic boron go-plus.json http://purl.obolibrary.org/obo/CHEBI_33610 CHEBI:18019 biolink:ChemicalSubstance L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18019 CHEBI:18016 biolink:ChemicalSubstance 3',4',5-trihydroxy-3,6,7-trimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18016 chebi_ph7_3 CHEBI:18014 biolink:ChemicalSubstance CMP-3-deoxy-alpha-D-manno-octulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18014 CHEBI:18015 biolink:ChemicalSubstance oxidized Latia luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18015 chebi_ph7_3 UBERON:0004488 biolink:AnatomicalEntity musculature of pes Any collection of muscles that is part of a foot [Automatically generated definition]. go-plus.json musculature of foot|foot musculature|set of muscles of foot|muscle group of foot http://purl.obolibrary.org/obo/UBERON_0004488 CHEBI:18012 biolink:ChemicalSubstance fumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18012 UBERON:0004489 biolink:AnatomicalEntity musculature of manus Any collection of muscles that is part of a manus [Automatically generated definition]. go-plus.json musculature of hand|hand musculature|set of muscles of hand|muscle group of hand http://purl.obolibrary.org/obo/UBERON_0004489 CHEBI:18013 biolink:ChemicalSubstance 4-O-feruloyl-D-quinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18013 CHEBI:18010 biolink:ChemicalSubstance 3',4',5-trihydroxy-3,7-dimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18010 CHEBI:18011 biolink:ChemicalSubstance androstane-3alpha,17beta-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18011 chebi_ph7_3 UBERON:0004487 biolink:AnatomicalEntity musculature of forelimb zeugopod Any collection of muscles that is part of a lower arm [Automatically generated definition]. go-plus.json musculature of forearm|muscle group of forearm|set of muscles of forearm http://purl.obolibrary.org/obo/UBERON_0004487 CHEBI:33624 biolink:ChemicalSubstance bromophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33624 CHEBI:33625 biolink:ChemicalSubstance dibromophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33625 NCBITaxon:29000 biolink:OrganismalEntity Pucciniomycotina go-plus.json Urediniomycetes http://purl.obolibrary.org/obo/NCBITaxon_29000 CHEBI:33628 biolink:ChemicalSubstance elemental aluminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_33628 UBERON:0004473 biolink:AnatomicalEntity musculature of face Any collection of muscles that is part of a face. go-plus.json musculi faciei|entire facial musculature|set of muscles of face|muscle group of face|set of facial muscles|facial muscles http://purl.obolibrary.org/obo/UBERON_0004473 UBERON:0004474 biolink:AnatomicalEntity musculature of arm Any collection of muscles that is part of an arm [Automatically generated definition]. go-plus.json muscle group of arm|arm musculature|set of muscles of arm|arm muscle system http://purl.obolibrary.org/obo/UBERON_0004474 UBERON:0004471 biolink:AnatomicalEntity musculature of pectoral girdle A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles. go-plus.json muscle group of pectoral girdle|pectoral girdle musculature|pectoral girdle muscles|set of muscles of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0004471 CHEBI:18009 biolink:ChemicalSubstance NADP(+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18009 CHEBI:33620 biolink:ChemicalSubstance aluminium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33620 UBERON:0004470 biolink:AnatomicalEntity musculature of pelvic girdle Any collection of muscles that is part of a pelvic girdle [Automatically generated definition]. go-plus.json set of muscles of pelvis|muscle group of pelvis|muscular system of pelvis|muscle group of pelvic girdle|pelvic girdle musculature|pelvic girdle muscles|set of muscles of pelvic girdle|pelvic girdle muscle system http://purl.obolibrary.org/obo/UBERON_0004470 CHEBI:18007 biolink:ChemicalSubstance 3-[hydroxy(oxido)phosphoranyl]pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18007 CHEBI:18005 biolink:ChemicalSubstance keto-phenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18005 chebi_ph7_3 UBERON:0004479 biolink:AnatomicalEntity musculature of trunk Any collection of muscles that is part of a trunk [Automatically generated definition]. go-plus.json muscle group of trunk|muscular system of trunk|set of muscles of trunk http://purl.obolibrary.org/obo/UBERON_0004479 CHEBI:18003 biolink:ChemicalSubstance 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18003 CHEBI:18004 biolink:ChemicalSubstance D-hamamelose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18004 chebi_ph7_3 CHEBI:18002 biolink:ChemicalSubstance (-)-secologanin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18002 chebi_ph7_3 UBERON:0004478 biolink:AnatomicalEntity musculature of larynx The collection of muscles that are part of the larynx. go-plus.json set of muscles of larynx|muscle group of larynx|laryngeal muscles set|laryngeal muscles|set of laryngeal muscles http://purl.obolibrary.org/obo/UBERON_0004478 UBERON:0004475 biolink:AnatomicalEntity musculature of hip The collection of muscles that form attachments to the hip skeleton. go-plus.json muscle group of hip|hip musculature|set of muscles of hip http://purl.obolibrary.org/obo/UBERON_0004475 UBERON:0004476 biolink:AnatomicalEntity musculature of shoulder The collection of muscles that form attachments to the shoulder skeleton. go-plus.json set of muscles of shoulder|muscle group of shoulder http://purl.obolibrary.org/obo/UBERON_0004476 CHEBI:18000 biolink:ChemicalSubstance aralkylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18000 CHEBI:82608 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_82608 CHEBI:82609 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_82609 CHEBI:82606 biolink:ChemicalSubstance 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82606 chebi_ph7_3 CHEBI:82607 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_82607 CHEBI:82605 biolink:ChemicalSubstance 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol-5'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82605 chebi_ph7_3 CHEBI:82611 biolink:ChemicalSubstance 2-O,3-dimethylflaviolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_82611 CHEBI:82612 biolink:ChemicalSubstance S-methyl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82612 chebi_ph7_3 CHEBI:82610 biolink:ChemicalSubstance 6-linalyl-2-O,3-dimethylflaviolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_82610 CHEBI:33608 biolink:ChemicalSubstance hydrogen molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33608 CHEBI:33609 biolink:ChemicalSubstance elemental boron go-plus.json http://purl.obolibrary.org/obo/CHEBI_33609 CHEBI:82628 biolink:ChemicalSubstance 11(R)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82628 chebi_ph7_3 CHEBI:82629 biolink:ChemicalSubstance prostaglandin G2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82629 chebi_ph7_3 CHEBI:82626 biolink:ChemicalSubstance 15(R)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82626 chebi_ph7_3 CHEBI:82627 biolink:ChemicalSubstance 15(R)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_82627 NCBITaxon:44689 biolink:OrganismalEntity Dictyostelium discoideum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_44689 CHEBI:82620 biolink:ChemicalSubstance L-tyrosine-O-phosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82620 chebi_ph7_3 CHEBI:82639 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82639 chebi_ph7_3 CHEBI:82637 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82637 chebi_ph7_3 CHEBI:82635 biolink:ChemicalSubstance 4-nitrophenyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82635 chebi_ph7_3 CHEBI:82633 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-D-galactosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82633 chebi_ph7_3 CHEBI:67008 biolink:ChemicalSubstance kynureninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67008 CHEBI:82631 biolink:ChemicalSubstance N-threonyl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82631 CHEBI:67001 biolink:ChemicalSubstance hypusinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67001 CHEBI:82632 biolink:ChemicalSubstance phytochrome chromophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_82632 CHEBI:67009 biolink:ChemicalSubstance S-adenosyl-L-homocysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67009 GO:0044382 biolink:BiologicalProcess CLRC complex localization to heterochromatin The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation. go-plus.json CLRC ubiquitin ligase complex localization to heterochromatin|CLRC ubiquitin ligase complex localisation to heterochromatin http://purl.obolibrary.org/obo/GO_0044382 CHEBI:18085 biolink:ChemicalSubstance glycosaminoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_18085 GO:0044383 biolink:CellularComponent host chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044383 CHEBI:18086 biolink:ChemicalSubstance indol-3-ylacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18086 chebi_ph7_3 GO:0044380 biolink:BiologicalProcess protein localization to cytoskeleton A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. go-plus.json protein localisation to cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 CHEBI:18083 biolink:ChemicalSubstance 1-methyladenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18083 chebi_ph7_3 GO:0044381 biolink:BiologicalProcess glucose import in response to insulin stimulus The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus. go-plus.json cellular glucose import in response to insulin stimulus http://purl.obolibrary.org/obo/GO_0044381 CHEBI:18084 biolink:ChemicalSubstance testololactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18084 chebi_ph7_3 CHEBI:18081 biolink:ChemicalSubstance 3-hexaprenyl-4,5-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18081 CHEBI:18082 biolink:ChemicalSubstance 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18082 chebi_ph7_3 CHEBI:18080 biolink:ChemicalSubstance 5-oxo-2,5-dihydro-2-furylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18080 GO:0044388 biolink:MolecularActivity small protein activating enzyme binding Binding to a small protein activating enzyme, such as ubiquitin-activating enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0044388 GO:0044389 biolink:MolecularActivity ubiquitin-like protein ligase binding Binding to a ubiquitin-like protein ligase, such as ubiquitin-ligase. go-plus.json small conjugating protein ligase binding|E3 protein ligase binding http://purl.obolibrary.org/obo/GO_0044389 GO:0044386 biolink:CellularComponent integral to host endoplasmic reticulum membrane Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. Occurring in a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044386 GO:0044387 biolink:BiologicalProcess negative regulation of protein kinase activity by regulation of protein phosphorylation The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0044387 GO:0044384 biolink:CellularComponent host outer membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell. go-plus.json host cell outer membrane http://purl.obolibrary.org/obo/GO_0044384 GO:0044385 biolink:CellularComponent integral to membrane of host cell Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Occurring in a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044385 CHEBI:57682 biolink:ChemicalSubstance coformycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57682 chebi_ph7_3 CHEBI:57683 biolink:ChemicalSubstance dolichyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57683 chebi_ph7_3 CHEBI:57680 biolink:ChemicalSubstance sinapoyltartronate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57680 chebi_ph7_3 CHEBI:57681 biolink:ChemicalSubstance cis-2-chloro-4-carboxylatomethylenebut-2-en-1,4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_57681 chebi_ph7_3 CHEBI:57688 biolink:ChemicalSubstance S-formylglutathionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57688 chebi_ph7_3 CHEBI:57689 biolink:ChemicalSubstance 2,2-dialkylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57689 chebi_ph7_3 CHEBI:18078 biolink:ChemicalSubstance 2-dehydro-3-deoxy-L-rhamnonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18078 CHEBI:57684 biolink:ChemicalSubstance beta-D-glucose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57684 chebi_ph7_3 CHEBI:57685 biolink:ChemicalSubstance sn-glycerol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57685 chebi_ph7_3 CHEBI:18077 biolink:ChemicalSubstance dTTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_18077 GO:0044393 biolink:CellularComponent microspike A dynamic, actin-rich projection extending from the surface of a migrating animal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044393 GO:0044394 biolink:BiologicalProcess protein malonylation The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group. go-plus.json http://purl.obolibrary.org/obo/GO_0044394 CHEBI:18075 biolink:ChemicalSubstance dTDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_18075 GO:0044391 biolink:CellularComponent ribosomal subunit Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0044391 CHEBI:18072 biolink:ChemicalSubstance 5-hydroxyisouric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18072 chebi_ph7_3 GO:0044392 biolink:BiologicalProcess peptidyl-lysine malonylation The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine. RESID:AA0568 go-plus.json lysine malonylation http://purl.obolibrary.org/obo/GO_0044392 CHEBI:18073 biolink:ChemicalSubstance xanthoaphin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18073 CHEBI:18070 biolink:ChemicalSubstance cytochrome c go-plus.json http://purl.obolibrary.org/obo/CHEBI_18070 UBERON:0004409 biolink:AnatomicalEntity distal epiphysis of phalanx of manus A distal epiphysis that is part of a phalanx of manus [Automatically generated definition]. go-plus.json head of phalanx of finger|distal epiphysis of phalanx of hand|distal epiphysis of phalanx of finger|distal end of phalanx of hand|ungual tuberosity of distal phalanx of finger|head of phalanx of hand http://purl.obolibrary.org/obo/UBERON_0004409 GO:0044390 biolink:MolecularActivity ubiquitin-like protein conjugating enzyme binding Binding to a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme. go-plus.json E2 protein ligase binding|small protein conjugating enzyme binding http://purl.obolibrary.org/obo/GO_0044390 CHEBI:18071 biolink:ChemicalSubstance (methylthio)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18071 chebi_ph7_3 UBERON:0004406 biolink:AnatomicalEntity distal epiphysis of femur A distal epiphysis that is part of a femur [Automatically generated definition]. go-plus.json distal femoral epiphysis|distal head of femur http://purl.obolibrary.org/obo/UBERON_0004406 GO:0044399 biolink:BiologicalProcess multi-species biofilm formation A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. go-plus.json multi-species biofilm formation on inanimate substrate|multi-species submerged biofilm formation|multi-species surface biofilm formation|multi-species biofilm formation in or on host organism http://purl.obolibrary.org/obo/GO_0044399 GO:0044397 biolink:BiologicalProcess obsolete actin cortical patch internalization OBSOLETE. A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044397 CHEBI:43034 biolink:ChemicalSubstance 7,8-didemethyl-8-hydroxy-5-deazariboflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_43034 GO:0044398 biolink:BiologicalProcess envenomation resulting in induction of edema in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation. go-plus.json envenomation resulting in induction of oedema in other organism http://purl.obolibrary.org/obo/GO_0044398 CHEBI:43035 biolink:ChemicalSubstance (R)-hydratropic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43035 GO:0044395 biolink:BiologicalProcess protein targeting to vacuolar membrane The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0044395 GO:0044396 biolink:BiologicalProcess actin cortical patch organization A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis. go-plus.json actin cortical patch organisation http://purl.obolibrary.org/obo/GO_0044396 CHEBI:57671 biolink:ChemicalSubstance 1-ammonio-1-deoxy-scyllo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_57671 chebi_ph7_3 CHEBI:57672 biolink:ChemicalSubstance 7-O-acetylsalutaridinol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57672 chebi_ph7_3 CHEBI:57670 biolink:ChemicalSubstance N-acylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57670 chebi_ph7_3 CHEBI:1015 biolink:ChemicalSubstance 2-aminobenzenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1015 UBERON:0004415 biolink:AnatomicalEntity proximal epiphysis of metatarsal bone A proximal epiphysis that is part of a metatarsal bone [Automatically generated definition]. go-plus.json basis ossis metatarsi|base of metatarsal bone|proximal end of metatarsal bone|upper end of metatarsal bone http://purl.obolibrary.org/obo/UBERON_0004415 CHEBI:57679 biolink:ChemicalSubstance hypotaurocyamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57679 chebi_ph7_3 UBERON:0004416 biolink:AnatomicalEntity proximal epiphysis of metacarpal bone A proximal epiphysis that is part of a metacarpal bone [Automatically generated definition]. go-plus.json proximal end of metacarpal bone|metacarpal bone base|upper end of metacarpal bone|basis ossis metacarpi|base of metacarpal bone http://purl.obolibrary.org/obo/UBERON_0004416 CHEBI:57677 biolink:ChemicalSubstance sn-3-O-(geranylgeranyl)glycerol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57677 chebi_ph7_3 UBERON:0004414 biolink:AnatomicalEntity proximal epiphysis of phalanx of manus A proximal epiphysis that is part of a phalanx of manus [Automatically generated definition]. go-plus.json basal epiphysis of phalanx of finger|basis phalangis manus|base of phalanx of finger|proximal epiphysis of phalanx of hand|proximal epiphysis of phalanx of finger http://purl.obolibrary.org/obo/UBERON_0004414 CHEBI:57678 biolink:ChemicalSubstance 3-mercaptopyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57678 chebi_ph7_3 UBERON:0004411 biolink:AnatomicalEntity proximal epiphysis of humerus The upper extremity of the humerus (proximal humerus) consists of a large rounded head joined to the body by a constricted portion called the neck, and two eminences, the greater and lesser tubercles. go-plus.json head of the humerus|proximal end of humerus|proximal humeral epiphysis|upper extremity of humerus|upper end of humerus|humeral head|proximal humerus http://purl.obolibrary.org/obo/UBERON_0004411 CHEBI:18067 biolink:ChemicalSubstance phylloquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18067 chebi_ph7_3 UBERON:0004412 biolink:AnatomicalEntity proximal epiphysis of femur A proximal epiphysis that is part of a femur [Automatically generated definition]. go-plus.json proximal femoral epiphysis|capital femoral epiphysis http://purl.obolibrary.org/obo/UBERON_0004412 CHEBI:57676 biolink:ChemicalSubstance questin-2-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57676 chebi_ph7_3 CHEBI:57673 biolink:ChemicalSubstance 2'-deoxyguanosine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57673 chebi_ph7_3 CHEBI:18065 biolink:ChemicalSubstance deacetylcephalosporin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_18065 UBERON:0004410 biolink:AnatomicalEntity distal epiphysis of fibula A distal epiphysis that is part of a fibula [Automatically generated definition]. go-plus.json lower end of fibula|distal end of fibula http://purl.obolibrary.org/obo/UBERON_0004410 CHEBI:18066 biolink:ChemicalSubstance UDP-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18066 CHEBI:57674 biolink:ChemicalSubstance N-acylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57674 chebi_ph7_3 CHEBI:33693 biolink:ChemicalSubstance oxygen hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_33693 CHEBI:57660 biolink:ChemicalSubstance myo-inositol 1,3,4,6-tetrakisphosphate(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57660 chebi_ph7_3 CHEBI:57661 biolink:ChemicalSubstance O-succinyl-L-homoserinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57661 chebi_ph7_3 CHEBI:33694 biolink:ChemicalSubstance biomacromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_33694 CHEBI:33695 biolink:ChemicalSubstance information biomacromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_33695 CHEBI:33696 biolink:ChemicalSubstance nucleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33696 CHEBI:140810 biolink:ChemicalSubstance beta-D-glucosamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140810 chebi_ph7_3 CHEBI:33697 biolink:ChemicalSubstance ribonucleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33697 CHEBI:43029 biolink:ChemicalSubstance L-erythro-7,8-dihydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_43029 chebi_ph7_3 CHEBI:33699 biolink:ChemicalSubstance messenger RNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_33699 UBERON:0004404 biolink:AnatomicalEntity distal epiphysis of humerus A distal epiphysis that is part of a humerus [Automatically generated definition]. go-plus.json lower end of humerus|distal end of humerus http://purl.obolibrary.org/obo/UBERON_0004404 CHEBI:57668 biolink:ChemicalSubstance D-ornithinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57668 chebi_ph7_3 UBERON:0004405 biolink:AnatomicalEntity distal epiphysis of tibia A distal epiphysis that is part of a tibia [Automatically generated definition]. go-plus.json lower end of tibia|distal end of tibia http://purl.obolibrary.org/obo/UBERON_0004405 CHEBI:57666 biolink:ChemicalSubstance N-acyl-D-mannosamine 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57666 chebi_ph7_3 UBERON:0004402 biolink:AnatomicalEntity bone tissue of proximal epiphysis A portion of bone tissue that is part of a proximal epiphysis [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004402 CHEBI:57667 biolink:ChemicalSubstance dADP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57667 chebi_ph7_3 CHEBI:57664 biolink:ChemicalSubstance 6-hydroxynicotinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57664 chebi_ph7_3 UBERON:0004400 biolink:AnatomicalEntity bone tissue of epiphysis A portion of bone tissue that is part of a epiphysis [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004400 UBERON:0004401 biolink:AnatomicalEntity bone tissue of distal epiphysis A portion of bone tissue that is part of a distal epiphysis [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004401 CHEBI:57665 biolink:ChemicalSubstance neryl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57665 chebi_ph7_3 CHEBI:57662 biolink:ChemicalSubstance S-carboxylatomethyl-L-cysteine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57662 chebi_ph7_3 CHEBI:18098 biolink:ChemicalSubstance CMP-N-glycoloyl-beta-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18098 CHEBI:140817 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_140817 chebi_ph7_3 CHEBI:57663 biolink:ChemicalSubstance 2-caffeoylisocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57663 chebi_ph7_3 CHEBI:33692 biolink:ChemicalSubstance hydrides go-plus.json http://purl.obolibrary.org/obo/CHEBI_33692 CHEBI:18099 biolink:ChemicalSubstance cyclohexanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18099 chebi_ph7_3 CHEBI:18094 biolink:ChemicalSubstance 1,4-dihydroxy-2-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18094 CHEBI:18095 biolink:ChemicalSubstance trans-4-hydroxy-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_18095 CHEBI:18092 biolink:ChemicalSubstance 8'-apo-beta-carotenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18092 chebi_ph7_3 CHEBI:18093 biolink:ChemicalSubstance 17,21-dihydroxy-5beta-pregnane-3,11,20-trione go-plus.json http://purl.obolibrary.org/obo/CHEBI_18093 chebi_ph7_3 CHEBI:18090 biolink:ChemicalSubstance 3-aminopropanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_18090 CHEBI:18091 biolink:ChemicalSubstance asparagusic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18091 CHEBI:57657 biolink:ChemicalSubstance 11-O-demethyl-17-O-deacetylvindolinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57657 chebi_ph7_3 CHEBI:57658 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57658 chebi_ph7_3 CHEBI:57655 biolink:ChemicalSubstance 3-dehydro-L-gulonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57655 chebi_ph7_3 CHEBI:57656 biolink:ChemicalSubstance 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57656 chebi_ph7_3 CHEBI:18089 biolink:ChemicalSubstance N-benzoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18089 CHEBI:57653 biolink:ChemicalSubstance 2-deoxy-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57653 chebi_ph7_3 CHEBI:57654 biolink:ChemicalSubstance undecaprenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57654 chebi_ph7_3 CHEBI:57651 biolink:ChemicalSubstance 2-deoxy-D-ribose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57651 chebi_ph7_3 CHEBI:18087 biolink:ChemicalSubstance myo-inositol polyphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18087 CHEBI:18088 biolink:ChemicalSubstance formononetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18088 CHEBI:57652 biolink:ChemicalSubstance chondroitin D-glucuronate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57652 chebi_ph7_3 CHEBI:18041 biolink:ChemicalSubstance (S)-lactaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18041 chebi_ph7_3 CHEBI:18042 biolink:ChemicalSubstance (S)-2,3-dihydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18042 OBO:cl#has_not_completed biolink:OntologyClass has_not_completed has_not_completed go-plus.json http://purl.obolibrary.org/obo/cl#has_not_completed CHEBI:18040 biolink:ChemicalSubstance erythro-5-hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18040 CHEBI:57649 biolink:ChemicalSubstance dTDP-4-dehydro-6-deoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57649 chebi_ph7_3 UBERON:0004462 biolink:AnatomicalEntity musculature of body wall Any collection of muscles that is part of a body wall [Automatically generated definition]. go-plus.json body wall musculature|body wall muscles http://purl.obolibrary.org/obo/UBERON_0004462 CHEBI:33671 biolink:ChemicalSubstance heteropolycyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33671 UBERON:0004463 biolink:AnatomicalEntity musculature of hindlimb stylopod Any collection of muscles that is part of a hindlimb stylopod (upper leg / thigh)[Automatically generated definition]. go-plus.json muscle group of thigh|thigh musculature|set of muscles of thigh|musculature of thigh http://purl.obolibrary.org/obo/UBERON_0004463 CHEBI:33672 biolink:ChemicalSubstance heterobicyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33672 CHEBI:33673 biolink:ChemicalSubstance zinc group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33673 UBERON:0004461 biolink:AnatomicalEntity skeletal musculature of head Any collection of skeletal muscles that is part of a head [Automatically generated definition]. go-plus.json muscle group of head|muscles of head|head musculature|musculi capitis|set of muscles of head http://purl.obolibrary.org/obo/UBERON_0004461 CHEBI:33674 biolink:ChemicalSubstance s-block molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33674 CHEBI:33675 biolink:ChemicalSubstance p-block molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33675 CHEBI:33676 biolink:ChemicalSubstance d-block molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33676 CHEBI:57646 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57646 chebi_ph7_3 CHEBI:18038 biolink:ChemicalSubstance GDP-L-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18038 CHEBI:57647 biolink:ChemicalSubstance 3-(4-hydroxy-3,5-diiodophenyl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57647 chebi_ph7_3 CHEBI:18039 biolink:ChemicalSubstance N-phospho-L-lombricine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18039 CHEBI:18036 biolink:ChemicalSubstance triphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18036 chebi_ph7_3 UBERON:0004468 biolink:AnatomicalEntity set of muscles of vertebral column go-plus.json muscle group of vertebral column http://purl.obolibrary.org/obo/UBERON_0004468 CHEBI:57644 biolink:ChemicalSubstance chlorogenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57644 chebi_ph7_3 UBERON:0004469 biolink:AnatomicalEntity musculature of back Any collection of muscles that is part of a back [Automatically generated definition]. go-plus.json muscle group of back|musculi dorsi|muscles of back|set of muscles of back http://purl.obolibrary.org/obo/UBERON_0004469 CHEBI:18037 biolink:ChemicalSubstance 3-oxolauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18037 CHEBI:18034 biolink:ChemicalSubstance 4-fumarylacetoacetate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18034 chebi_ph7_3 UBERON:0004466 biolink:AnatomicalEntity musculature of leg Any collection of muscles that is part of a lower leg or upper leg [Automatically generated definition]. go-plus.json leg muscle system http://purl.obolibrary.org/obo/UBERON_0004466 CHEBI:57642 biolink:ChemicalSubstance glycerone phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57642 chebi_ph7_3 CHEBI:18035 biolink:ChemicalSubstance diglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_18035 chebi_ph7_3 CHEBI:57643 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57643 chebi_ph7_3 UBERON:0004467 biolink:AnatomicalEntity musculature of pharynx the collection of muscles that acts on the pharynx. go-plus.json set of muscles of pharynx|pharyngeal musculature http://purl.obolibrary.org/obo/UBERON_0004467 CHEBI:57640 biolink:ChemicalSubstance 1,6-dihydroxy-2-methylcyclohexa-2,4-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57640 chebi_ph7_3 UBERON:0004464 biolink:AnatomicalEntity musculature of thorax Any collection of muscles that is part of a thorax [Automatically generated definition]. go-plus.json muscles of thorax|thoracic musculature|set of muscles of thorax|musculi thoracis|muscle group of thorax http://purl.obolibrary.org/obo/UBERON_0004464 CHEBI:18032 biolink:ChemicalSubstance 4-amino-2-methyl-5-phosphooxymethylpyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18032 UBERON:0004465 biolink:AnatomicalEntity musculature of neck Any collection of muscles that is part of a neck [Automatically generated definition]. go-plus.json set of muscles of neck|muscle group of neck|musculi colli|musculi cervicis|cervical muscles|muscles of neck|neck musculature http://purl.obolibrary.org/obo/UBERON_0004465 CHEBI:18033 biolink:ChemicalSubstance 2-formylphenylformamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18033 chebi_ph7_3 CHEBI:57641 biolink:ChemicalSubstance 2,4-dichloro-5-oxo-2,5-dihydro-2-furylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57641 chebi_ph7_3 CHEBI:33670 biolink:ChemicalSubstance heteromonocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33670 CHEBI:18030 biolink:ChemicalSubstance quercetin 3,4'-bissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18030 CHEBI:57639 biolink:ChemicalSubstance 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57639 chebi_ph7_3 CHEBI:57637 biolink:ChemicalSubstance 2-methylene-3-methylsuccinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57637 chebi_ph7_3 CHEBI:57638 biolink:ChemicalSubstance GDP-6-deoxy-alpha-D-talose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57638 chebi_ph7_3 UBERON:0004451 biolink:AnatomicalEntity trunk or cervical vertebra A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra. go-plus.json presacral vertebra http://purl.obolibrary.org/obo/UBERON_0004451 UBERON:0004452 biolink:AnatomicalEntity carpal region A mesopodium that is part of a manus. Includes as parts the carpal skeleton and associated tissues[cjm]. The anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, the flexor retinaculum, and the extensor retinaculum[WP,unvetted] go-plus.json wrist|wrist region|hand mesopodium|carpal limb segment|carpus of fore-paw|articulatio radiocarpea|carpal segment|manus mesopodium|regio carpalis|carpus|fore basipodium|fore mesopodium http://purl.obolibrary.org/obo/UBERON_0004452 CHEBI:18029 biolink:ChemicalSubstance dihydromacarpine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18029 chebi_ph7_3 CHEBI:18027 biolink:ChemicalSubstance (-)-aristolochene go-plus.json http://purl.obolibrary.org/obo/CHEBI_18027 chebi_ph7_3 CHEBI:57635 biolink:ChemicalSubstance UDP-alpha-D-galacturonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57635 chebi_ph7_3 CHEBI:57633 biolink:ChemicalSubstance (S)-3-(indol-3-yl)-2-oxobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57633 chebi_ph7_3 CHEBI:18025 biolink:ChemicalSubstance 2-hydroxypropyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18025 CHEBI:18026 biolink:ChemicalSubstance 2,3-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18026 CHEBI:57634 biolink:ChemicalSubstance beta-D-fructofuranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57634 chebi_ph7_3 UBERON:0004455 biolink:AnatomicalEntity neurula embryo An embryo at the neurula stage. go-plus.json neurula http://purl.obolibrary.org/obo/UBERON_0004455 CHEBI:18023 biolink:ChemicalSubstance sirohydrochlorin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18023 CHEBI:57631 biolink:ChemicalSubstance dTDP-L-dihydrostreptose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57631 chebi_ph7_3 UBERON:0004456 biolink:AnatomicalEntity entire sense organ system Sum of all sensory systems in an organism. go-plus.json sense organ system http://purl.obolibrary.org/obo/UBERON_0004456 CHEBI:18024 biolink:ChemicalSubstance D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18024 CHEBI:57632 biolink:ChemicalSubstance UDP-alpha-D-xylose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57632 chebi_ph7_3 CHEBI:18021 biolink:ChemicalSubstance phosphoenolpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18021 UBERON:0004453 biolink:AnatomicalEntity metacarpus region A metapodium region that is part of a manus. go-plus.json forelimb cannon region|metacarpal part of manus|metacarpal region|forelimb equine cannon region|metacarpal part of hand|metacarpus|distal segment of hand proper http://purl.obolibrary.org/obo/UBERON_0004453 UBERON:0004454 biolink:AnatomicalEntity tarsal region mesopodial segment of the pes, including the tarsal skeleton and associated tissues. go-plus.json tarsal limb segment|hock|articulatio talocruralis|ankle region|ankle|hind basipodium|hind mesopodium http://purl.obolibrary.org/obo/UBERON_0004454 CHEBI:18022 biolink:ChemicalSubstance thiocyanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18022 chebi_ph7_3 CHEBI:57630 biolink:ChemicalSubstance gamma-amino-beta-hydroxybutyric acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57630 chebi_ph7_3 CHEBI:18063 biolink:ChemicalSubstance 2-O-acyl-3-O-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18063 chebi_ph7_3 CHEBI:18064 biolink:ChemicalSubstance 3-hydroxyisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18064 CHEBI:18062 biolink:ChemicalSubstance 4-guanidinobutanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18062 CHEBI:57628 biolink:ChemicalSubstance 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57628 chebi_ph7_3 CHEBI:57629 biolink:ChemicalSubstance D-glucopyranose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57629 chebi_ph7_3 CHEBI:18060 biolink:ChemicalSubstance 1-haloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_18060 chebi_ph7_3 CHEBI:57626 biolink:ChemicalSubstance limonin 17-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57626 chebi_ph7_3 CHEBI:57627 biolink:ChemicalSubstance 1D-myo-inositol 1,4,5,6-tetrakisphosphate(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57627 chebi_ph7_3 CHEBI:33658 biolink:ChemicalSubstance arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33658 CHEBI:33659 biolink:ChemicalSubstance organic aromatic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33659 CHEBI:33650 biolink:ChemicalSubstance acyclic acetylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33650 PATO:0002124 biolink:OntologyClass laminar go-plus.json http://purl.obolibrary.org/obo/PATO_0002124 CHEBI:33653 biolink:ChemicalSubstance aliphatic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33653 CHEBI:33654 biolink:ChemicalSubstance alicyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33654 CHEBI:33655 biolink:ChemicalSubstance aromatic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33655 UBERON:0004448 biolink:AnatomicalEntity distal epiphysis of phalanx A distal epiphysis that is part of a phalanx [Automatically generated definition]. go-plus.json head of phalanx http://purl.obolibrary.org/obo/UBERON_0004448 UBERON:0004449 biolink:AnatomicalEntity cerebral artery One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004449 UBERON:0004446 biolink:AnatomicalEntity epiphysis of phalanx An epiphysis that is part of a phalanx [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004446 CHEBI:18058 biolink:ChemicalSubstance oxamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18058 CHEBI:57623 biolink:ChemicalSubstance prenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57623 chebi_ph7_3 CHEBI:18059 biolink:ChemicalSubstance lipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18059 UBERON:0004447 biolink:AnatomicalEntity proximal epiphysis of phalanx A proximal epiphysis that is part of a phalanx [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004447 CHEBI:57620 biolink:ChemicalSubstance poly(ribitol phosphate) polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57620 CHEBI:18056 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18056 chebi_ph7_3 CHEBI:57621 biolink:ChemicalSubstance 2-benzylsuccinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57621 chebi_ph7_3 CHEBI:18057 biolink:ChemicalSubstance vellosimine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18057 chebi_ph7_3 CHEBI:18054 biolink:ChemicalSubstance diphthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18054 CHEBI:18052 biolink:ChemicalSubstance loganate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18052 chebi_ph7_3 CHEBI:18053 biolink:ChemicalSubstance 1-aminocyclopropanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18053 CHEBI:57619 biolink:ChemicalSubstance CDP-abequose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57619 chebi_ph7_3 CHEBI:18050 biolink:ChemicalSubstance L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18050 CHEBI:18051 biolink:ChemicalSubstance L-aspartic 4-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18051 CHEBI:57617 biolink:ChemicalSubstance alpha-D-galactosyl undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57617 chebi_ph7_3 CHEBI:57618 biolink:ChemicalSubstance FMNH2(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57618 chebi_ph7_3 CHEBI:57616 biolink:ChemicalSubstance L-methioninium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_57616 chebi_ph7_3 CHEBI:33661 biolink:ChemicalSubstance monocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33661 CHEBI:33662 biolink:ChemicalSubstance annulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33662 CHEBI:33663 biolink:ChemicalSubstance cyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33663 CHEBI:33664 biolink:ChemicalSubstance monocyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33664 CHEBI:33666 biolink:ChemicalSubstance polycyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33666 CHEBI:18049 biolink:ChemicalSubstance piperidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18049 CHEBI:57613 biolink:ChemicalSubstance phosphatidylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57613 chebi_ph7_3 CHEBI:57614 biolink:ChemicalSubstance ITP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57614 CHEBI:18047 biolink:ChemicalSubstance dihydrolipoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18047 CHEBI:57612 biolink:ChemicalSubstance phosphonatoguanidiniumylacetate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57612 chebi_ph7_3 CHEBI:18048 biolink:ChemicalSubstance DIMBOA go-plus.json http://purl.obolibrary.org/obo/CHEBI_18048 chebi_ph7_3 CHEBI:57610 biolink:ChemicalSubstance N(alpha),N(alpha)-dimethyl-L-histidine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57610 chebi_ph7_3 CHEBI:18046 biolink:ChemicalSubstance 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18046 CHEBI:18043 biolink:ChemicalSubstance ricinine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18043 chebi_ph7_3 CHEBI:18044 biolink:ChemicalSubstance dialkyl ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18044 chebi_ph7_3 GO:0019580 biolink:BiologicalProcess galactarate metabolic process The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose. go-plus.json D-galactarate metabolic process|D-galactarate metabolism|mucic acid metabolic process|galactarate metabolism|mucic acid metabolism http://purl.obolibrary.org/obo/GO_0019580 GO:0019581 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019581 GO:0044544 biolink:BiologicalProcess envenomation resulting in plasminogen activation in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0044544 GO:0044545 biolink:CellularComponent NSL complex A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1. go-plus.json non-specific lethal complex http://purl.obolibrary.org/obo/GO_0044545 GO:0044542 biolink:BiologicalProcess plasminogen activation in other organism The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044542 GO:0044543 biolink:BiologicalProcess envenomation resulting in zymogen activation in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form. go-plus.json http://purl.obolibrary.org/obo/GO_0044543 GO:0044540 biolink:MolecularActivity L-cystine L-cysteine-lyase (deaminating) Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide. RHEA:24927|KEGG_REACTION:R02408|EC:4.4.1.1 go-plus.json http://purl.obolibrary.org/obo/GO_0044540 GO:0044541 biolink:BiologicalProcess zymogen activation in other organism The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044541 GO:0044548 biolink:MolecularActivity S100 protein binding Binding to a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS. go-plus.json S100 alpha binding|S100 binding|S100 beta binding http://purl.obolibrary.org/obo/GO_0044548 GO:0044549 biolink:MolecularActivity GTP cyclohydrolase binding Binding to a GTP cyclohydrolase. go-plus.json GTP cyclohydrolase I binding http://purl.obolibrary.org/obo/GO_0044549 GO:0044546 biolink:BiologicalProcess NLRP3 inflammasome complex assembly The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell. go-plus.json NALP3 inflammasome complex assembly|NLRP3 inflammasome activation http://purl.obolibrary.org/obo/GO_0044546 GO:0019579 biolink:BiologicalProcess aldaric acid catabolic process The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group. go-plus.json aldaric acid degradation|aldaric acid breakdown|aldaric acid catabolism http://purl.obolibrary.org/obo/GO_0019579 GO:0044547 biolink:MolecularActivity DNA topoisomerase binding Binding to a DNA topoisomerase. go-plus.json DNA topoisomerase I binding http://purl.obolibrary.org/obo/GO_0044547 GO:0019577 biolink:BiologicalProcess aldaric acid metabolic process The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group. go-plus.json aldaric acid metabolism http://purl.obolibrary.org/obo/GO_0019577 GO:0019578 biolink:BiologicalProcess aldaric acid biosynthetic process The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group. go-plus.json aldaric acid synthesis|aldaric acid formation|aldaric acid biosynthesis|aldaric acid anabolism http://purl.obolibrary.org/obo/GO_0019578 PR:000018271 biolink:Protein interferon gamma proteolytic cleavage product An interferon gamma that has been processed by proteolytic cleavage. go-plus.json IFNG/ClvPrd http://purl.obolibrary.org/obo/PR_000018271 GO:0019575 biolink:BiologicalProcess obsolete sucrose catabolic process, using beta-fructofuranosidase OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26). MetaCyc:SUCUTIL-PWY go-plus.json sucrose catabolism, using beta-fructofuranosidase|sucrose catabolic process, using beta-fructofuranosidase|sucrose breakdown, using beta-fructofuranosidase|sucrose degradation, using beta-fructofuranosidase http://purl.obolibrary.org/obo/GO_0019575 GO:0019576 biolink:BiologicalProcess aerobic fructose catabolic process The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen. go-plus.json aerobic fructose breakdown|aerobic fructose catabolism|aerobic fructose degradation http://purl.obolibrary.org/obo/GO_0019576 GO:0019573 biolink:BiologicalProcess D-arabinose catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate. MetaCyc:DARABCAT-PWY go-plus.json D-arabinose degradation to xylulose 5-phosphate|D-arabinose breakdown to xylulose 5-phosphate http://purl.obolibrary.org/obo/GO_0019573 GO:0019574 biolink:BiologicalProcess sucrose catabolic process via 3'-ketosucrose The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose. MetaCyc:SUCROSEUTIL2-PWY go-plus.json sucrose breakdown, using glucoside 3-dehydrogenase|sucrose degradation, using glucoside 3-dehydrogenase|sucrose catabolism, using glucoside 3-dehydrogenase|sucrose catabolic process to D-glucose|sucrose catabolic process, using glucoside 3-dehydrogenase http://purl.obolibrary.org/obo/GO_0019574 GO:0019571 biolink:BiologicalProcess D-arabinose catabolic process The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose. go-plus.json D-arabinose degradation|D-arabinose breakdown|D-arabinose catabolism http://purl.obolibrary.org/obo/GO_0019571 GO:0019572 biolink:BiologicalProcess L-arabinose catabolic process The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose. go-plus.json L-arabinose breakdown|L-arabinose catabolism|L-arabinose degradation http://purl.obolibrary.org/obo/GO_0019572 GO:0019591 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019591 GO:0019592 biolink:BiologicalProcess mannitol catabolic process The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. MetaCyc:PWY-3861|MetaCyc:MANNIDEG-PWY go-plus.json mannitol degradation|mannitol breakdown|mannitol catabolism http://purl.obolibrary.org/obo/GO_0019592 GO:0019590 biolink:BiologicalProcess L-arabitol catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate. MetaCyc:LARABITOLUTIL-PWY go-plus.json L-arabitol breakdown to xylulose 5-phosphate|L-arabitol and xylitol degradation|L-arabitol utilization|L-arabitol degradation to xylulose 5-phosphate http://purl.obolibrary.org/obo/GO_0019590 GO:0044555 biolink:BiologicalProcess negative regulation of heart rate in other organism Any process that stops, prevents or reduces the frequency of heart contraction of another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044555 GO:0044556 biolink:BiologicalProcess envenomation resulting in negative regulation of heart rate of other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044556 GO:0044553 biolink:BiologicalProcess modulation of biological quality in other organism Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. go-plus.json regulation of biological quality in other organism http://purl.obolibrary.org/obo/GO_0044553 GO:0044554 biolink:BiologicalProcess modulation of heart rate in other organism Any process that modulates the frequency or rate of heart contraction of another organism. go-plus.json regulation of heart rate in other organism http://purl.obolibrary.org/obo/GO_0044554 GO:0044551 biolink:BiologicalProcess envenomation resulting in vasodilation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism. go-plus.json envenomation resulting in regulation of vasodilation in other organism|envenomation resulting in modulation of vasodilation in other organism http://purl.obolibrary.org/obo/GO_0044551 GO:0044552 biolink:BiologicalProcess vasodilation in other organism A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism. go-plus.json modulation of vasodilation in other organism|regulation of vasodilation in other organism http://purl.obolibrary.org/obo/GO_0044552 GO:0044550 biolink:BiologicalProcess secondary metabolite biosynthetic process The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. go-plus.json secondary metabolite biosynthesis http://purl.obolibrary.org/obo/GO_0044550 GO:0044559 biolink:BiologicalProcess envenomation resulting in modulation of voltage-gated potassium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044559 GO:0044557 biolink:BiologicalProcess relaxation of smooth muscle A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. go-plus.json smooth muscle relaxation http://purl.obolibrary.org/obo/GO_0044557 GO:0044558 biolink:BiologicalProcess uterine smooth muscle relaxation A process in which the extent of smooth muscle contraction is reduced in the uterus. go-plus.json smooth muscle relaxation of the uterus http://purl.obolibrary.org/obo/GO_0044558 GO:0019588 biolink:BiologicalProcess anaerobic glycerol catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP. go-plus.json glycerol fermentation http://purl.obolibrary.org/obo/GO_0019588 GO:0019589 biolink:BiologicalProcess anaerobic glycerol catabolic process to propane-1,3-diol The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water. MetaCyc:GOLPDLCAT-PWY go-plus.json glycerol fermentation to 1,3-propanediol|glycerol fermentation to propane-1,3-diol http://purl.obolibrary.org/obo/GO_0019589 PR:000018263 biolink:Protein amino acid chain An organic amino compound that is a polymer of amino acid chain components (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. go-plus.json peptide|polypeptide http://purl.obolibrary.org/obo/PR_000018263 GO:0019586 biolink:BiologicalProcess galacturonate metabolic process The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. go-plus.json galacturonate metabolism http://purl.obolibrary.org/obo/GO_0019586 GO:0019587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019587 GO:0019584 biolink:BiologicalProcess galactonate catabolic process The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid. MetaCyc:GALACTCAT-PWY go-plus.json galactonate degradation|galactonate breakdown|galactonate catabolism http://purl.obolibrary.org/obo/GO_0019584 GO:0019585 biolink:BiologicalProcess glucuronate metabolic process The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. Wikipedia:Glucuronic_acid go-plus.json glucuronate metabolism http://purl.obolibrary.org/obo/GO_0019585 PR:000018264 biolink:Protein proteolytic cleavage product A protein that is produced as the result of proteolytic processing of a longer protein. go-plus.json peptide|ClvPrd|polypeptide http://purl.obolibrary.org/obo/PR_000018264 GO:0019582 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019582 GO:0019583 biolink:BiologicalProcess galactonate metabolic process The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose. go-plus.json galactonate metabolism http://purl.obolibrary.org/obo/GO_0019583 GO:0044566 biolink:BiologicalProcess chondrocyte activation A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_0044566 GO:0044567 biolink:CellularComponent primary cell wall cellulose synthase complex A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein. go-plus.json primary cell wall CESA complex|primary cell-wall cellulose synthase complex http://purl.obolibrary.org/obo/GO_0044567 GO:0044564 biolink:BiologicalProcess envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044564 GO:0044565 biolink:BiologicalProcess dendritic cell proliferation The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_0044565 GO:0044562 biolink:BiologicalProcess envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044562 GO:0044563 biolink:BiologicalProcess envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism. go-plus.json voltage-dependence of activation shift (to the left) http://purl.obolibrary.org/obo/GO_0044563 GO:0044560 biolink:BiologicalProcess envenomation resulting in modulation of ion channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism. go-plus.json envenomation resulting in regulation of ion channel activity in other organism http://purl.obolibrary.org/obo/GO_0044560 GO:0044561 biolink:BiologicalProcess modulation of ion channel activity in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism. go-plus.json regulation of ion channel activity in other organism http://purl.obolibrary.org/obo/GO_0044561 GO:0019559 biolink:BiologicalProcess histidine catabolic process to imidazol-5-yl-lactate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate. MetaCyc:HISTDEG-PWY go-plus.json histidine breakdown to imidazol-5-yl-lactate|histidine degradation to imidazol-5-yl-lactate http://purl.obolibrary.org/obo/GO_0019559 GO:0044568 biolink:CellularComponent secondary cell wall cellulose synthase complex A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4. go-plus.json secondary cell wall CesA complex|secondary cell wall CESA complex|secondary cell-wall cellulose synthase complex http://purl.obolibrary.org/obo/GO_0044568 GO:0019557 biolink:BiologicalProcess histidine catabolic process to glutamate and formate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate. go-plus.json histidine breakdown to glutamate and formate|histidine degradation to glutamate and formate http://purl.obolibrary.org/obo/GO_0019557 GO:0019558 biolink:BiologicalProcess histidine catabolic process to 2-oxoglutarate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate. go-plus.json histidine catabolic process to alpha-oxoglutarate|histidine catabolism to alpha-ketoglutarate|histidine catabolic process to 2-ketoglutarate|histidine degradation to 2-oxoglutarate|histidine catabolism to 2-ketoglutarate|histidine breakdown to 2-oxoglutarate|histidine catabolism to alpha-oxoglutarate|histidine catabolic process to alpha-ketoglutarate http://purl.obolibrary.org/obo/GO_0019558 GO:0044569 biolink:CellularComponent [Ni-Fe] hydrogenase complex A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer. go-plus.json Ni-Fe hydrogenase complex|nickel-iron hydrogenase complex http://purl.obolibrary.org/obo/GO_0044569 GO:0019555 biolink:BiologicalProcess glutamate catabolic process to ornithine The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine. MetaCyc:GLUTORN-PWY go-plus.json glutamate breakdown to ornithine|glutamate degradation to ornithine http://purl.obolibrary.org/obo/GO_0019555 GO:0019556 biolink:BiologicalProcess histidine catabolic process to glutamate and formamide The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide. MetaCyc:HISDEG-PWY go-plus.json histidine breakdown to glutamate and formamide|histidine degradation to glutamate and formamide http://purl.obolibrary.org/obo/GO_0019556 GO:0019553 biolink:BiologicalProcess glutamate catabolic process via L-citramalate The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate. MetaCyc:GLUDEG-II-PWY go-plus.json glutamate degradation via L-citramalate|glutamate breakdown via L-citramalate http://purl.obolibrary.org/obo/GO_0019553 GO:0019554 biolink:BiologicalProcess glutamate catabolic process to oxaloacetate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate. go-plus.json glutamate breakdown to oxaloacetate|glutamate degradation to oxaloacetate http://purl.obolibrary.org/obo/GO_0019554 GO:0019551 biolink:BiologicalProcess glutamate catabolic process to 2-oxoglutarate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate. MetaCyc:GLUTAMATE-DEG1-PWY|MetaCyc:PWY-5766 go-plus.json glutamate catabolic process to alpha-oxoglutarate|glutamate catabolic process to 2-ketoglutarate|glutamate catabolism to alpha-ketoglutarate|glutamate degradation to 2-oxoglutarate|glutamate catabolism to 2-ketoglutarate|glutamate breakdown to 2-oxoglutarate|glutamate catabolism to alpha-oxoglutarate|glutamate catabolic process to alpha-ketoglutarate http://purl.obolibrary.org/obo/GO_0019551 GO:0019552 biolink:BiologicalProcess glutamate catabolic process via 2-hydroxyglutarate The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP. MetaCyc:P162-PWY go-plus.json glutamate fermentation via 2-hydroxyglutarate http://purl.obolibrary.org/obo/GO_0019552 GO:0019550 biolink:BiologicalProcess glutamate catabolic process to aspartate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate. MetaCyc:GLUTDEG-PWY go-plus.json glutamate breakdown to aspartate|glutamate degradation to aspartate http://purl.obolibrary.org/obo/GO_0019550 GO:0044570 biolink:CellularComponent starch utilization system complex A bacterial cell envelope-associated multiprotein system, which binds and degrades starch. go-plus.json Sus complex http://purl.obolibrary.org/obo/GO_0044570 GO:0019570 biolink:BiologicalProcess L-arabinose catabolic process to 2-oxoglutarate The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate. go-plus.json L-arabinose degradation to 2-oxoglutarate|L-arabinose catabolic process to 2-ketoglutarate|L-arabinose catabolism to 2-ketoglutarate|L-arabinose breakdown to 2-oxoglutarate|L-arabinose catabolism to alpha-oxoglutarate|L-arabinose catabolic process to alpha-oxoglutarate|L-arabinose catabolic process to alpha-ketoglutarate|L-arabinose catabolism to alpha-ketoglutarate http://purl.obolibrary.org/obo/GO_0019570 GO:0044577 biolink:BiologicalProcess xylose catabolic process to ethanol The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol. go-plus.json xylose catabolism to ethanol http://purl.obolibrary.org/obo/GO_0044577 CHEBI:140883 biolink:ChemicalSubstance TG(18:2/18:2/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140883 chebi_ph7_3 GO:0044578 biolink:BiologicalProcess butyryl-CoA biosynthetic process The chemical reactions and pathway resulting in the formation of butyryl-CoA. go-plus.json butyryl-CoA biosynthesis http://purl.obolibrary.org/obo/GO_0044578 GO:0044575 biolink:BiologicalProcess cellulosome assembly The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0044575 GO:0044576 biolink:BiologicalProcess pentose catabolic process to ethanol The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol. go-plus.json pentose catabolism to ethanol http://purl.obolibrary.org/obo/GO_0044576 GO:0044573 biolink:BiologicalProcess nitrogenase P cluster assembly The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide. go-plus.json nitrogenase P cluster biosynthesis|nitrogenase P cluster maturation http://purl.obolibrary.org/obo/GO_0044573 GO:0044574 biolink:BiologicalProcess starch utilization system complex assembly The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan. go-plus.json SUS complex assembly|assembly of starch utilization system complex http://purl.obolibrary.org/obo/GO_0044574 GO:0044571 biolink:BiologicalProcess [2Fe-2S] cluster assembly The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster. go-plus.json 2Fe-2S cluster assembly|[2Fe-2S] cluster biosynthetic process http://purl.obolibrary.org/obo/GO_0044571 GO:0044572 biolink:BiologicalProcess [4Fe-4S] cluster assembly The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster. go-plus.json [4Fe-4S] cluster biosynthetic process|4Fe-4S cluster assembly http://purl.obolibrary.org/obo/GO_0044572 GO:0044579 biolink:BiologicalProcess butyryl-CoA biosynthetic process from acetyl-CoA The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA. go-plus.json butyryl-CoA biosynthesis from acetyl-CoA http://purl.obolibrary.org/obo/GO_0044579 GO:0019568 biolink:BiologicalProcess arabinose catabolic process The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose. go-plus.json arabinose degradation|arabinose breakdown|arabinose catabolism http://purl.obolibrary.org/obo/GO_0019568 GO:0019569 biolink:BiologicalProcess L-arabinose catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate. MetaCyc:ARABCAT-PWY go-plus.json L-arabinose degradation to xylulose 5-phosphate|L-arabinose breakdown to xylulose 5-phosphate http://purl.obolibrary.org/obo/GO_0019569 GO:0019566 biolink:BiologicalProcess arabinose metabolic process The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides. go-plus.json arabinose metabolism http://purl.obolibrary.org/obo/GO_0019566 GO:0019567 biolink:BiologicalProcess arabinose biosynthetic process The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose. go-plus.json arabinose synthesis|arabinose formation|arabinose biosynthesis|arabinose anabolism http://purl.obolibrary.org/obo/GO_0019567 GO:0019564 biolink:BiologicalProcess aerobic glycerol catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen. MetaCyc:PWY0-381 go-plus.json aerobic glycerol catabolism|aerobic glycerol degradation|aerobic glycerol fermentation|aerobic glycerol breakdown http://purl.obolibrary.org/obo/GO_0019564 GO:0019565 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019565 GO:0019562 biolink:BiologicalProcess obsolete L-phenylalanine catabolic process to phosphoenolpyruvate OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-phenylalanine into other compounds, including phosphoenolpyruvate. MetaCyc:PHENYLALANINE-DEG1-PWY go-plus.json phenylalanine breakdown to phosphoenolpyruvate|phenylalanine degradation to phosphoenolpyruvate http://purl.obolibrary.org/obo/GO_0019562 GO:0019563 biolink:BiologicalProcess glycerol catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. MetaCyc:PWY0-381|MetaCyc:PWY-4261 go-plus.json glycerol breakdown|glycerol catabolism|glycerol degradation http://purl.obolibrary.org/obo/GO_0019563 GO:0019560 biolink:BiologicalProcess histidine catabolic process to hydantoin-5-propionate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate. MetaCyc:HISHP-PWY go-plus.json histidine breakdown to hydantoin-5-propionate|histidine degradation to hydantoin-5-propionate http://purl.obolibrary.org/obo/GO_0019560 GO:0019561 biolink:BiologicalProcess anaerobic phenylalanine oxidation The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde. MetaCyc:ANAPHENOXI-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019561 GO:0044580 biolink:BiologicalProcess butyryl-CoA catabolic process The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA. go-plus.json butyryl-CoA catabolism http://purl.obolibrary.org/obo/GO_0044580 GO:0044581 biolink:BiologicalProcess butyryl-CoA catabolic process to butyrate The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate. go-plus.json butyryl-CoA catabolism to butyrate http://purl.obolibrary.org/obo/GO_0044581 GO:0044588 biolink:MolecularActivity laminaribiose binding Binding to laminaribiose, a disaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_0044588 GO:0044589 biolink:MolecularActivity pectin binding Binding to pectin. go-plus.json http://purl.obolibrary.org/obo/GO_0044589 GO:0044586 biolink:MolecularActivity cellotetraose binding Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose. go-plus.json http://purl.obolibrary.org/obo/GO_0044586 GO:0044587 biolink:MolecularActivity cellopentaose binding Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose. go-plus.json http://purl.obolibrary.org/obo/GO_0044587 GO:0044584 biolink:MolecularActivity cellodextrin binding Binding to a cellodextrin, a glucose polymer of 2 or more glucose monomers. go-plus.json http://purl.obolibrary.org/obo/GO_0044584 GO:0044585 biolink:MolecularActivity cellobiose binding Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose. go-plus.json http://purl.obolibrary.org/obo/GO_0044585 GO:0044582 biolink:BiologicalProcess butyryl-CoA catabolic process to butanol The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol. go-plus.json butyryl-CoA catabolism to butanol http://purl.obolibrary.org/obo/GO_0044582 GO:0044583 biolink:MolecularActivity cellotriose binding Binding to cellotriose. go-plus.json http://purl.obolibrary.org/obo/GO_0044583 GO:0019539 biolink:BiologicalProcess hydroxymate-containing siderophore biosynthetic process The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+). go-plus.json http://purl.obolibrary.org/obo/GO_0019539 GO:0019537 biolink:BiologicalProcess vibriobactin biosynthetic process The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae. go-plus.json vibriobactin biosynthetic process, peptide modification|vibriobactin synthesis|vibriobactin formation|vibriobactin biosynthesis|vibriobactin biosynthetic process, peptide formation|vibriobactin anabolism http://purl.obolibrary.org/obo/GO_0019537 GO:0019538 biolink:BiologicalProcess protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification. Wikipedia:Protein_metabolism go-plus.json protein metabolism|multicellular organismal protein metabolic process|protein metabolic process and modification|protein metabolism and modification http://purl.obolibrary.org/obo/GO_0019538 goslim_mouse|goslim_agr|goslim_pir|goslim_plant|goslim_flybase_ribbon GO:0019535 biolink:MolecularActivity ferric-vibriobactin transmembrane transporter activity Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0019535 GO:0019536 biolink:BiologicalProcess vibriobactin metabolic process The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae. go-plus.json vibriobactin metabolism http://purl.obolibrary.org/obo/GO_0019536 GO:0019533 biolink:BiologicalProcess cellobiose transport The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose. go-plus.json http://purl.obolibrary.org/obo/GO_0019533 GO:0019534 biolink:MolecularActivity toxin transmembrane transporter activity Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0019534 GO:0019531 biolink:MolecularActivity oxalate transmembrane transporter activity Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. go-plus.json oxalic acid transporter activity http://purl.obolibrary.org/obo/GO_0019531 GO:0019532 biolink:BiologicalProcess oxalate transport The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. go-plus.json ethanedioate transport|ethanedioic acid transport|oxalic acid transport http://purl.obolibrary.org/obo/GO_0019532 UBERON:0004500 biolink:AnatomicalEntity skeletal muscle tissue of deltoid A portion of skeletal muscle tissue that is part of a deltoid [Automatically generated definition]. go-plus.json skeletal muscle tissue of deltoid muscle http://purl.obolibrary.org/obo/UBERON_0004500 GO:0019530 biolink:BiologicalProcess taurine metabolic process The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. go-plus.json taurine metabolism http://purl.obolibrary.org/obo/GO_0019530 GO:0044591 biolink:BiologicalProcess response to amylopectin A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0044591 GO:0044592 biolink:BiologicalProcess response to pullulan A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0044592 GO:0044590 biolink:MolecularActivity iron-sulfur-molybdenum cofactor binding Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase. go-plus.json FeMoco binding|FeMo co binding http://purl.obolibrary.org/obo/GO_0044590 GO:0044599 biolink:CellularComponent AP-5 adaptor complex An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo. go-plus.json adaptor protein-5 adaptor complex http://purl.obolibrary.org/obo/GO_0044599 GO:0044597 biolink:BiologicalProcess daunorubicin metabolic process The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer. go-plus.json http://purl.obolibrary.org/obo/GO_0044597 GO:0044598 biolink:BiologicalProcess doxorubicin metabolic process The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy. go-plus.json http://purl.obolibrary.org/obo/GO_0044598 GO:0044595 biolink:MolecularActivity decaprenyldihydroxybenzoate methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate. MetaCyc:RXN-9282|RHEA:44492|Reactome:R-HSA-2162193 go-plus.json http://purl.obolibrary.org/obo/GO_0044595 GO:0044596 biolink:MolecularActivity 3-demethylubiquinol-10 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10. Reactome:R-HSA-2162186|MetaCyc:RXN-9237|RHEA:44412 go-plus.json http://purl.obolibrary.org/obo/GO_0044596 GO:0044593 biolink:BiologicalProcess iron-sulfur-molybdenum cofactor assembly The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase. go-plus.json FeMoco biosynthetic process|iron molybdenum cofactor biosynthetic process|iron molybdenum cofactor biosynthesis|FeMoco assembly|iron molybdenum cofactor assembly http://purl.obolibrary.org/obo/GO_0044593 GO:0044594 biolink:MolecularActivity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+. RHEA:24612 go-plus.json http://purl.obolibrary.org/obo/GO_0044594 CHEBI:57594 biolink:ChemicalSubstance O-carbamoyl-L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57594 chebi_ph7_3 CHEBI:57595 biolink:ChemicalSubstance L-histidine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57595 chebi_ph7_3 CHEBI:57592 biolink:ChemicalSubstance cyclohexylsulfamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57592 chebi_ph7_3 CHEBI:57593 biolink:ChemicalSubstance 3-guanidinopropanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57593 chebi_ph7_3 CHEBI:57590 biolink:ChemicalSubstance O-phosphonato-L-homoserine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57590 chebi_ph7_3 GO:0019548 biolink:BiologicalProcess arginine catabolic process to spermine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine. MetaCyc:ARGSPECAT-PWY go-plus.json arginine degradation to spermine|arginine breakdown to spermine http://purl.obolibrary.org/obo/GO_0019548 GO:0019549 biolink:BiologicalProcess glutamate catabolic process to succinate via succinate semialdehyde The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase. MetaCyc:PWY-4321 go-plus.json glutamate catabolic process to succinate via pyruvate-dependent GABA-transaminase activity|glutamate breakdown to succinate|glutamate degradation to succinate http://purl.obolibrary.org/obo/GO_0019549 GO:0019546 biolink:BiologicalProcess arginine deiminase pathway The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase. MetaCyc:ARGDEGRAD-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019546 GO:0019547 biolink:BiologicalProcess arginine catabolic process to ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine. go-plus.json arginine breakdown to ornithine|arginine degradation to ornithine http://purl.obolibrary.org/obo/GO_0019547 GO:0019544 biolink:BiologicalProcess arginine catabolic process to glutamate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate. MetaCyc:ARGASEDEG-PWY|MetaCyc:ARG-GLU-PWY go-plus.json arginine breakdown to glutamate|arginine degradation to glutamate http://purl.obolibrary.org/obo/GO_0019544 GO:0019545 biolink:BiologicalProcess arginine catabolic process to succinate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate. MetaCyc:ARGDEG-IV-PWY|MetaCyc:AST-PWY|MetaCyc:ARGDEG-V-PWY|MetaCyc:ARGDEG-III-PWY go-plus.json arginine breakdown to succinate|arginine degradation to succinate http://purl.obolibrary.org/obo/GO_0019545 GO:0019542 biolink:BiologicalProcess propionate biosynthetic process The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid. go-plus.json propionate biosynthesis|propionate formation|propionate anabolism|propionate synthesis http://purl.obolibrary.org/obo/GO_0019542 GO:0019543 biolink:BiologicalProcess propionate catabolic process The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid. go-plus.json propionate degradation|propionate breakdown|propionate catabolism http://purl.obolibrary.org/obo/GO_0019543 GO:0019540 biolink:BiologicalProcess catechol-containing siderophore biosynthetic process The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+). go-plus.json http://purl.obolibrary.org/obo/GO_0019540 CHEBI:57598 biolink:ChemicalSubstance 1-benzyl-2-methyl-1,2,3,4-tetrahydroisoquinolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57598 chebi_ph7_3 GO:0019541 biolink:BiologicalProcess propionate metabolic process The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants. go-plus.json propionate metabolism|propanoate metabolic process|propanoate metabolism http://purl.obolibrary.org/obo/GO_0019541 CHEBI:57599 biolink:ChemicalSubstance N-acyl-D-glucosamine 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57599 chebi_ph7_3 CHEBI:57596 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-D-galactose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57596 chebi_ph7_3 CHEBI:57597 biolink:ChemicalSubstance sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57597 chebi_ph7_3 GO:0019519 biolink:BiologicalProcess pentitol metabolic process The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule. go-plus.json pentitol metabolism http://purl.obolibrary.org/obo/GO_0019519 CHEBI:57583 biolink:ChemicalSubstance 6-imino-5-oxocyclohexa-1,3-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57583 chebi_ph7_3 CHEBI:57584 biolink:ChemicalSubstance aldehydo-D-glucose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57584 chebi_ph7_3 GO:0019517 biolink:BiologicalProcess L-threonine catabolic process to D-lactate The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate. MetaCyc:THRDLCTCAT-PWY go-plus.json L-threonine breakdown to D-lactate|L-threonine catabolism to D-lactate|L-threonine degradation to D-lactate|threonine catabolic process to D-lactate|L-threonine catabolic process to methylglyoxal|L-threonine catabolic process to pyruvate|L-threonine catabolic process to (R)-lactate http://purl.obolibrary.org/obo/GO_0019517 CHEBI:57581 biolink:ChemicalSubstance (S)-coclaurinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57581 chebi_ph7_3 GO:0019518 biolink:BiologicalProcess L-threonine catabolic process to glycine The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine. MetaCyc:THREONINE-DEG2-PWY go-plus.json threonine catabolic process to glycine|L-threonine degradation to glycine|L-threonine catabolic process to pyruvate|L-threonine catabolism to glycine|L-threonine breakdown to glycine http://purl.obolibrary.org/obo/GO_0019518 CHEBI:57582 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57582 chebi_ph7_3 GO:0019515 biolink:BiologicalProcess lactose catabolic process via UDP-galactose The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose. go-plus.json lactose degradation via UDP-galactose|lactose breakdown via UDP-galactose http://purl.obolibrary.org/obo/GO_0019515 CHEBI:57580 biolink:ChemicalSubstance diphthamide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57580 chebi_ph7_3 GO:0019516 biolink:BiologicalProcess lactate oxidation The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons. go-plus.json http://purl.obolibrary.org/obo/GO_0019516 GO:0019513 biolink:BiologicalProcess lactose catabolic process, using glucoside 3-dehydrogenase The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13). MetaCyc:LACTOSEUTIL-PWY go-plus.json lactose breakdown, using glucoside 3-dehydrogenase|lactose degradation, using glucoside 3-dehydrogenase http://purl.obolibrary.org/obo/GO_0019513 GO:0019514 biolink:BiologicalProcess obsolete lactose hydrolysis OBSOLETE. (Was not defined before being made obsolete). go-plus.json lactose hydrolysis http://purl.obolibrary.org/obo/GO_0019514 GO:0019511 biolink:BiologicalProcess peptidyl-proline hydroxylation The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline. go-plus.json http://purl.obolibrary.org/obo/GO_0019511 GO:0019512 biolink:BiologicalProcess lactose catabolic process via tagatose-6-phosphate The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate. MetaCyc:LACTOSECAT-PWY go-plus.json lactose breakdown via tagatose-6-phosphate|lactose degradation via tagatose-6-phosphate http://purl.obolibrary.org/obo/GO_0019512 CHEBI:57589 biolink:ChemicalSubstance O-acetyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57589 chebi_ph7_3 GO:0019510 biolink:BiologicalProcess S-adenosylhomocysteine catabolic process The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine. MetaCyc:ADENOSYLHOMOCYSCAT-PWY go-plus.json S-adenosylhomocysteine degradation|S-adenosylhomocysteine breakdown|S-adenosylhomocysteine catabolism http://purl.obolibrary.org/obo/GO_0019510 CHEBI:57587 biolink:ChemicalSubstance stipitatate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57587 CHEBI:57588 biolink:ChemicalSubstance phosphatidyl-N-methylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57588 chebi_ph7_3 CHEBI:57585 biolink:ChemicalSubstance discadenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57585 chebi_ph7_3 CHEBI:57586 biolink:ChemicalSubstance biotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57586 chebi_ph7_3 CHEBI:57572 biolink:ChemicalSubstance UDP-D-apiose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57572 chebi_ph7_3 GO:0019528 biolink:BiologicalProcess D-arabitol catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate. MetaCyc:DARABITOLUTIL-PWY go-plus.json D-arabitol degradation|D-arabitol utilization|D-arabitol degradation to xylulose 5-phosphate|D-arabitol breakdown to xylulose 5-phosphate http://purl.obolibrary.org/obo/GO_0019528 CHEBI:57570 biolink:ChemicalSubstance dolichyl diphosphooligosaccharide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57570 chebi_ph7_3 GO:0019529 biolink:BiologicalProcess taurine catabolic process The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. MetaCyc:TAURINEDEG-PWY go-plus.json taurine degradation|taurine catabolism|taurine breakdown http://purl.obolibrary.org/obo/GO_0019529 GO:0019526 biolink:BiologicalProcess pentitol biosynthetic process The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule. go-plus.json pentitol anabolism|pentitol synthesis|pentitol formation|pentitol biosynthesis http://purl.obolibrary.org/obo/GO_0019526 GO:0019527 biolink:BiologicalProcess pentitol catabolic process The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule. go-plus.json pentitol breakdown|pentitol catabolism|pentitol degradation http://purl.obolibrary.org/obo/GO_0019527 GO:0019524 biolink:BiologicalProcess keto-D-gluconate catabolic process The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose. MetaCyc:DHGLUCONATE-PYR-CAT-PWY go-plus.json keto-D-gluconate degradation|keto-D-gluconate breakdown|keto-D-gluconate catabolism http://purl.obolibrary.org/obo/GO_0019524 GO:0019525 biolink:BiologicalProcess keto-D-gluconate metabolic process The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose. go-plus.json keto-D-gluconate metabolism http://purl.obolibrary.org/obo/GO_0019525 GO:0019522 biolink:BiologicalProcess ketogluconate metabolic process The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group. MetaCyc:KETOGLUCONMET-PWY go-plus.json ketogluconate metabolism http://purl.obolibrary.org/obo/GO_0019522 GO:0019523 biolink:BiologicalProcess L-idonate metabolic process The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. MetaCyc:IDNCAT-PWY go-plus.json L-idonate metabolism http://purl.obolibrary.org/obo/GO_0019523 CHEBI:57578 biolink:ChemicalSubstance 6-O-methylnorlaudanosolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57578 chebi_ph7_3 GO:0019520 biolink:BiologicalProcess aldonic acid metabolic process The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group. go-plus.json aldonic acid metabolism http://purl.obolibrary.org/obo/GO_0019520 CHEBI:57579 biolink:ChemicalSubstance D-fructose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57579 chebi_ph7_3 GO:0019521 biolink:BiologicalProcess D-gluconate metabolic process The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose. go-plus.json D-gluconate metabolism http://purl.obolibrary.org/obo/GO_0019521 CHEBI:57576 biolink:ChemicalSubstance 2,3-dihydroxy-2,3-dihydrobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57576 chebi_ph7_3 CHEBI:57577 biolink:ChemicalSubstance poly(glycerol phosphate) anion macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_57577 chebi_ph7_3 CHEBI:57575 biolink:ChemicalSubstance trans-5-O-(4-coumaroyl)-D-quinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57575 chebi_ph7_3 GO:0044500 biolink:BiologicalProcess envenomation resulting in negative regulation of blood pressure in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism. go-plus.json hypotensive activity in other organism http://purl.obolibrary.org/obo/GO_0044500 GO:0044501 biolink:BiologicalProcess modulation of signal transduction in other organism The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044501 GO:0044508 biolink:MolecularActivity glucagon-like peptide 1 receptor activity Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json http://purl.obolibrary.org/obo/GO_0044508 GO:0044509 biolink:BiologicalProcess envenomation resulting in modulation of signal transduction in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044509 GO:0044506 biolink:BiologicalProcess modulation of glucagon-like peptide receptor 1 activity in other organism The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism. go-plus.json regulation of glucagon-like peptide receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044506 GO:0044507 biolink:BiologicalProcess positive regulation of receptor activity in other organism A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044507 GO:0044504 biolink:BiologicalProcess modulation of receptor activity in other organism The process in which an organism effects a change in the activity of a receptor in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044504 GO:0044505 biolink:BiologicalProcess positive regulation of G protein-coupled receptor activity in other organism A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism. go-plus.json regulation of G-protein coupled receptor activity in other organism|positive regulation of G-protein coupled receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044505 GO:0044502 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044502 GO:0044503 biolink:BiologicalProcess modulation of G protein-coupled receptor activity in other organism The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism. go-plus.json modulation of G-protein coupled receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044503 GO:0044511 biolink:BiologicalProcess envenomation resulting in modulation of receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044511 GO:0044512 biolink:BiologicalProcess envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044512 GO:0044510 biolink:BiologicalProcess envenomation resulting in positive regulation of signal transduction in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044510 GO:0044519 biolink:BiologicalProcess envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism. go-plus.json envenomation resulting in regulation of vasoactive intestinal polypeptide receptor activity in other organism|envenomation resulting in regulation of VIP receptor activity in other organism|envenomation resulting in modulation of VIP receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044519 GO:0044517 biolink:BiologicalProcess modulation of vasoactive intestinal polypeptide receptor activity in other organism The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism. go-plus.json regulation of vasoactive intestinal polypeptide receptor activity in other organism|modulation of VIP receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044517 GO:0044518 biolink:BiologicalProcess positive regulation of vasoactive intestinal polypeptide receptor activity in other organism A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism. go-plus.json positive regulation of VIP receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044518 GO:0044515 biolink:BiologicalProcess envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044515 GO:0044516 biolink:BiologicalProcess positive regulation of glucagon-like peptide receptor 1 activity in other organism A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044516 GO:0044513 biolink:BiologicalProcess envenomation resulting in modulation of G protein-coupled receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism. go-plus.json envenomation resulting in modulation of G-protein coupled receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044513 GO:0044514 biolink:BiologicalProcess envenomation resulting in positive regulation of G protein-coupled receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism. go-plus.json envenomation resulting in positive regulation of G-protein coupled receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044514 GO:0044522 biolink:BiologicalProcess envenomation resulting in myocyte killing in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism. go-plus.json envenomation resulting in myocyte killing causing muscle damage in other organism http://purl.obolibrary.org/obo/GO_0044522 GO:0044523 biolink:BiologicalProcess envenomation resulting in damage of muscle extracellular matrix in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism. go-plus.json envenomation resulting in damage of muscle extracellular matrix causing muscle necrosis in other organism http://purl.obolibrary.org/obo/GO_0044523 GO:0044520 biolink:BiologicalProcess envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism. go-plus.json envenomation resulting in positive regulation of VIP receptor activity in other organism http://purl.obolibrary.org/obo/GO_0044520 GO:0044521 biolink:BiologicalProcess envenomation resulting in muscle damage in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044521 PR:000008878 biolink:Protein bone sialoprotein 2 A protein that is a translation product of the human IBSP gene or a 1:1 ortholog thereof. go-plus.json BNSP|BSP II|cell-binding sialoprotein|integrin-binding sialoprotein|IBSP|bone sialoprotein II http://purl.obolibrary.org/obo/PR_000008878 GO:0044528 biolink:BiologicalProcess regulation of mitochondrial mRNA stability Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0044528 GO:0044529 biolink:BiologicalProcess regulation of mitochondrial rRNA stability Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0044529 GO:0044526 biolink:BiologicalProcess formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide. go-plus.json http://purl.obolibrary.org/obo/GO_0044526 PR:000008875 biolink:Protein islet amyloid polypeptide A protein that is a translation product of the human IAPP gene or a 1:1 ortholog thereof. go-plus.json DAP|amylin|diabetes-associated peptide|IAPP|insulinoma amyloid peptide http://purl.obolibrary.org/obo/PR_000008875 GO:0044527 biolink:BiologicalProcess formation of peptidyl-cystine persulfide by sulphur transfer from H2S The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide. go-plus.json http://purl.obolibrary.org/obo/GO_0044527 GO:0044524 biolink:BiologicalProcess protein sulfhydration The modification of a protein amino acid by the addition of sulfur. go-plus.json http://purl.obolibrary.org/obo/GO_0044524 GO:0044525 biolink:BiologicalProcess peptidyl-cystine sulfhydration The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide. go-plus.json http://purl.obolibrary.org/obo/GO_0044525 GO:0019599 biolink:BiologicalProcess (R)-4-hydroxymandelate catabolic process The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid. MetaCyc:4-HYDROXYMANDELATE-DEGRADATION-PWY go-plus.json (R)-4-hydroxymandelate degradation|(R)-4-hydroxymandelate catabolism|(R)-4-hydroxymandelate breakdown http://purl.obolibrary.org/obo/GO_0019599 GO:0019597 biolink:BiologicalProcess (R)-mandelate catabolic process to benzoate The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate. go-plus.json (R)-mandelate degradation to benzoate|(R)-mandelate breakdown to benzoate http://purl.obolibrary.org/obo/GO_0019597 GO:0019598 biolink:BiologicalProcess (R)-mandelate catabolic process to catechol The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol. go-plus.json (R)-mandelate breakdown to catechol|(R)-mandelate degradation to catechol http://purl.obolibrary.org/obo/GO_0019598 GO:0019595 biolink:BiologicalProcess non-phosphorylated glucose catabolic process The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose. MetaCyc:NPGLUCAT-PWY go-plus.json non-phosphorylated glucose catabolism|non-phosphorylated glucose degradation|non-phosphorylated glucose breakdown http://purl.obolibrary.org/obo/GO_0019595 GO:0019596 biolink:BiologicalProcess mandelate catabolic process The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic. go-plus.json mandelate degradation|mandelate breakdown|mandelate catabolism http://purl.obolibrary.org/obo/GO_0019596 GO:0019593 biolink:BiologicalProcess mannitol biosynthetic process The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. MetaCyc:PWY-3881 go-plus.json mannitol anabolism|mannitol synthesis|mannitol biosynthesis|mannitol formation http://purl.obolibrary.org/obo/GO_0019593 GO:0019594 biolink:BiologicalProcess mannitol metabolic process The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. go-plus.json mannitol metabolism http://purl.obolibrary.org/obo/GO_0019594 GO:0044533 biolink:BiologicalProcess positive regulation of apoptotic process in other organism Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044533 GO:0044534 biolink:BiologicalProcess envenomation resulting in modulation of apoptotic process in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044534 GO:0044531 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044531 GO:0044532 biolink:BiologicalProcess modulation of apoptotic process in other organism A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism. go-plus.json regulation of apoptotic process in other organism http://purl.obolibrary.org/obo/GO_0044532 GO:0044530 biolink:CellularComponent supraspliceosomal complex Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing. go-plus.json supraspliceosome complex http://purl.obolibrary.org/obo/GO_0044530 GO:0044539 biolink:BiologicalProcess long-chain fatty acid import into cell The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json long-chain fatty acid uptake|long-chain fatty acid import http://purl.obolibrary.org/obo/GO_0044539 GO:0044537 biolink:BiologicalProcess regulation of circulating fibrinogen levels Any process that modulates the quantity of fibrinogen circulating in the bloodstream. go-plus.json http://purl.obolibrary.org/obo/GO_0044537 GO:0044538 biolink:CellularComponent host cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044538 GO:0044535 biolink:MolecularActivity very-long-chain fatty acyl-CoA oxidase activity Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide. EC:1.3.3.- go-plus.json very-long-chain acyl-CoA oxidase activity|VLC fatty-acyl-CoA oxidase activity|very long chain fatty-acyl-CoA oxidase activity http://purl.obolibrary.org/obo/GO_0044535 GO:0044536 biolink:BiologicalProcess envenomation resulting in depletion of circulating fibrinogen in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism. go-plus.json envenomation resulting in negative regulation of circulating fibrinogen in other organism http://purl.obolibrary.org/obo/GO_0044536 PR:000008888 biolink:Protein isocitrate dehydrogenase [NADP], mitochondrial A protein that is a translation product of the human IDH2 gene or a 1:1 ortholog thereof. go-plus.json oxalosuccinate decarboxylase|ICD-M|IDP|IDH2nadp|IDH|NADP(+)-specific ICDH http://purl.obolibrary.org/obo/PR_000008888 CHEBI:33515 biolink:ChemicalSubstance transition element cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33515 CHEBI:33516 biolink:ChemicalSubstance chromium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33516 CHEBI:33519 biolink:ChemicalSubstance tellurium oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33519 NCBITaxon:44542 biolink:OrganismalEntity gambiae species complex go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_44542 CHEBI:33510 biolink:ChemicalSubstance L-arabinonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33510 CHEBI:33511 biolink:ChemicalSubstance ribonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33511 CHEBI:33513 biolink:ChemicalSubstance alkaline earth cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33513 NCBITaxon:44537 biolink:OrganismalEntity Pyretophorus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_44537 NCBITaxon:44534 biolink:OrganismalEntity Cellia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_44534 CHEBI:33526 biolink:ChemicalSubstance mannonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33526 CHEBI:33527 biolink:ChemicalSubstance ribonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33527 CHEBI:33529 biolink:ChemicalSubstance idonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33529 NCBITaxon:68525 biolink:OrganismalEntity delta/epsilon subdivisions go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_68525 CHEBI:33520 biolink:ChemicalSubstance tellurium oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33520 CHEBI:33521 biolink:ChemicalSubstance metal atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33521 CHEBI:33522 biolink:ChemicalSubstance hydrogentellurite go-plus.json http://purl.obolibrary.org/obo/CHEBI_33522 NCBITaxon:379583 biolink:OrganismalEntity Feliformia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_379583 NCBITaxon:379584 biolink:OrganismalEntity Caniformia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_379584 CHEBI:33504 biolink:ChemicalSubstance alkali metal cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33504 CHEBI:33507 biolink:ChemicalSubstance diketoaldonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33507 CHEBI:33508 biolink:ChemicalSubstance glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33508 CHEBI:33509 biolink:ChemicalSubstance arabinonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33509 UBERON:0004590 biolink:AnatomicalEntity sphincter muscle A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. go-plus.json sphincter|circular muscle http://purl.obolibrary.org/obo/UBERON_0004590 NCBITaxon:1462606 biolink:OrganismalEntity Glycine subgen. Soja go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1462606 UBERON:0004538 biolink:AnatomicalEntity left kidney A kidney that is part of a left side of organism [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004538 UBERON:0004539 biolink:AnatomicalEntity right kidney A kidney that is part of a right side of organism [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004539 CHEBI:57561 biolink:ChemicalSubstance L-threonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57561 chebi_ph7_3 CHEBI:57562 biolink:ChemicalSubstance (R)-2-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57562 chebi_ph7_3 CHEBI:33595 biolink:ChemicalSubstance cyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33595 CHEBI:33596 biolink:ChemicalSubstance inorganic heterocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33596 CHEBI:57560 biolink:ChemicalSubstance long-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57560 chebi_ph7_3 CHEBI:33597 biolink:ChemicalSubstance homocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33597 CHEBI:33598 biolink:ChemicalSubstance carbocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33598 CHEBI:33599 biolink:ChemicalSubstance spiro compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33599 CHEBI:57569 biolink:ChemicalSubstance 2-dehydro-3-deoxy-6-phosphonato-D-gluconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57569 chebi_ph7_3 UBERON:0004548 biolink:AnatomicalEntity left eye An eye that is part of a left side of organism [Automatically generated definition]. go-plus.json left eyeball|left orbital part of face|left orbital region http://purl.obolibrary.org/obo/UBERON_0004548 CHEBI:57567 biolink:ChemicalSubstance N(6)-(1,2-dicarboxylatoethyl)-AMP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57567 chebi_ph7_3 CHEBI:57565 biolink:ChemicalSubstance serine phosphoethanolamine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57565 chebi_ph7_3 UBERON:0004544 biolink:AnatomicalEntity epididymis epithelium the layer of secretory cells which lines the epididymis go-plus.json epithelium of epididymis|epididymis epithelium http://purl.obolibrary.org/obo/UBERON_0004544 CHEBI:57566 biolink:ChemicalSubstance 2'-deoxycytosine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57566 chebi_ph7_3 CHEBI:57563 biolink:ChemicalSubstance 2-amino-4-oxopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57563 chebi_ph7_3 CHEBI:57564 biolink:ChemicalSubstance ADP-L-glycero-D-manno-heptose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57564 chebi_ph7_3 UBERON:0004529 biolink:AnatomicalEntity anatomical projection A projection or outgrowth of tissue from a larger body or organ. go-plus.json spine|papilla|protrusion|lamella|anatomical protrusion|lamellae|flange|projection|ridge|shelf|projection|shelves|ridges|processus|lamina|projections|flanges|laminae|anatomical process|organ process|process|processes|process of organ http://purl.obolibrary.org/obo/UBERON_0004529 UBERON:0004527 biolink:AnatomicalEntity alveolar process of maxilla The thickened ridge of bone that contains the tooth sockets on the maxilla. go-plus.json alveolar process of maxilla|maxilla alveolar process|processus alveolaris (maxilla)|posterior alveolar ridge|lower alveolar ridge|alveolar margin of maxilla|pars dentalis of maxilla|alveolar part of maxilla|processus alveolaris maxillae|alveolar ridge of maxilla http://purl.obolibrary.org/obo/UBERON_0004527 GO:0019508 biolink:BiologicalProcess 2,5-dihydroxypyridine catabolic process to fumarate The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate. MetaCyc:PWY-722 go-plus.json pyridine-2,5-diol catabolic process to fumarate|2,5-dihydroxypyridine degradation to fumarate|maleamate pathway|2,5-dihydroxypyridine breakdown to fumarate|2,5-dihydroxypyridine utilization http://purl.obolibrary.org/obo/GO_0019508 CHEBI:57551 biolink:ChemicalSubstance S-methyl 3-O-phosphonato-1-thio-D-glycerate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57551 chebi_ph7_3 GO:0019509 biolink:BiologicalProcess L-methionine salvage from methylthioadenosine The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine. MetaCyc:PWY-4361 go-plus.json methionine recycling|methionine salvage pathway|methionine salvage from methylthioadenosine|methionine regeneration http://purl.obolibrary.org/obo/GO_0019509 GO:0019506 biolink:BiologicalProcess phenylmercury acetate catabolic process The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group. MetaCyc:P641-PWY go-plus.json phenylmercury acetate degradation|phenylmercury acetate breakdown|phenylmercury acetate catabolism http://purl.obolibrary.org/obo/GO_0019506 GO:0019507 biolink:BiologicalProcess pyridine metabolic process The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor. go-plus.json pyridine metabolism http://purl.obolibrary.org/obo/GO_0019507 GO:0019504 biolink:BiologicalProcess stachydrine catabolic process The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline. MetaCyc:P561-PWY go-plus.json stachydrine degradation|stachydrine breakdown|stachydrine catabolism http://purl.obolibrary.org/obo/GO_0019504 GO:0019505 biolink:BiologicalProcess resorcinol metabolic process The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic. MetaCyc:P343-PWY go-plus.json resorcinol metabolism|1,3-benzenediol metabolic process|1,3-dihydroxybenzene metabolic process|1,3-dihydroxybenzene metabolism|1,3-benzenediol metabolism http://purl.obolibrary.org/obo/GO_0019505 GO:0019502 biolink:BiologicalProcess stachydrine metabolic process The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants. go-plus.json stachydrine metabolism http://purl.obolibrary.org/obo/GO_0019502 GO:0019503 biolink:BiologicalProcess stachydrine biosynthetic process The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline. go-plus.json stachydrine anabolism|stachydrine synthesis|stachydrine formation|stachydrine biosynthesis http://purl.obolibrary.org/obo/GO_0019503 UBERON:0004536 biolink:AnatomicalEntity lymph vasculature A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep. go-plus.json lymphatic vasculature|lymphatic vessels set|lymphatic trunks and ducts|lymphatic vessel network|set of lymphatic vessels|trunci et ductus lymphatici|lymph vessels http://purl.obolibrary.org/obo/UBERON_0004536 CHEBI:57558 biolink:ChemicalSubstance trans-2,3-epoxysuccinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57558 chebi_ph7_3 GO:0019500 biolink:BiologicalProcess cyanide catabolic process The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration. MetaCyc:P401-PWY go-plus.json cyanide degradation|cyanide breakdown|cyanide catabolism http://purl.obolibrary.org/obo/GO_0019500 CHEBI:57559 biolink:ChemicalSubstance alpha-D-xylose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57559 chebi_ph7_3 UBERON:0004537 biolink:AnatomicalEntity blood vasculature A vascular network consisting of blood vessels. go-plus.json blood vascular network|blood vessels|blood system|blood vessel system|set of blood vessels http://purl.obolibrary.org/obo/UBERON_0004537 GO:0019501 biolink:BiologicalProcess arsonoacetate catabolic process The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom. MetaCyc:P482-PWY go-plus.json arsonoacetate catabolism|arsonoacetate degradation|arsonoacetate breakdown http://purl.obolibrary.org/obo/GO_0019501 UBERON:0004534 biolink:AnatomicalEntity right testis A testis that is in the right side of the genitalia [Automatically generated definition]. go-plus.json right testicle http://purl.obolibrary.org/obo/UBERON_0004534 CHEBI:57556 biolink:ChemicalSubstance S-(3-carboxylatopropanoyl)glutathionate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57556 chebi_ph7_3 UBERON:0004535 biolink:AnatomicalEntity cardiovascular system Anatomical system that has as its parts the heart and blood vessels. go-plus.json Herz und Gefaesssystem|CV system http://purl.obolibrary.org/obo/UBERON_0004535 CHEBI:57557 biolink:ChemicalSubstance (R)-5-diphosphonatomevalonate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57557 chebi_ph7_3 CHEBI:57554 biolink:ChemicalSubstance tropinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57554 chebi_ph7_3 CHEBI:57555 biolink:ChemicalSubstance L-2-amino-4-chloropent-4-enoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57555 chebi_ph7_3 UBERON:0004533 biolink:AnatomicalEntity left testis A testis that is in the left side of the genitalia [Automatically generated definition]. go-plus.json left testicle http://purl.obolibrary.org/obo/UBERON_0004533 CHEBI:57552 biolink:ChemicalSubstance 2-oxopropyl-CoM(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57552 chebi_ph7_3 UBERON:0004530 biolink:AnatomicalEntity bony projection Anatomical projection that is composed of bone tissue. go-plus.json projection of bone|bony projections|bone process http://purl.obolibrary.org/obo/UBERON_0004530 CHEBI:57553 biolink:ChemicalSubstance P(1),P(4)-bis(5'-guanosyl) tetraphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57553 chebi_ph7_3 UBERON:0004518 biolink:AnatomicalEntity muscle of vertebral column A muscle that is attached to a vertebra of the vertebral column. go-plus.json vertebral column muscle http://purl.obolibrary.org/obo/UBERON_0004518 UBERON:0004516 biolink:AnatomicalEntity smooth muscle tissue of terminal bronchiole A portion of smooth muscle tissue that is part of a terminal bronchiole [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004516 CHEBI:57549 biolink:ChemicalSubstance N(2)-(carboxylatoacetyl)-D-tryptophanate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57549 chebi_ph7_3 CHEBI:33572 biolink:ChemicalSubstance resorcinols go-plus.json http://purl.obolibrary.org/obo/CHEBI_33572 CHEBI:33573 biolink:ChemicalSubstance tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33573 CHEBI:57540 biolink:ChemicalSubstance NAD(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57540 chebi_ph7_3 CHEBI:33574 biolink:ChemicalSubstance 4-methylthio-2-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33574 CHEBI:33575 biolink:ChemicalSubstance carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33575 CHEBI:33576 biolink:ChemicalSubstance sulfur-containing carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33576 CHEBI:33579 biolink:ChemicalSubstance main group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33579 UBERON:0004525 biolink:AnatomicalEntity cardiac muscle tissue of trabecula carnea of right ventricle A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004525 CHEBI:57547 biolink:ChemicalSubstance CDP-N-methylethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57547 chebi_ph7_3 UBERON:0004526 biolink:AnatomicalEntity cardiac muscle tissue of trabecula carnea of left ventricle A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004526 CHEBI:57548 biolink:ChemicalSubstance o-orsellinate depsidate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57548 chebi_ph7_3 CHEBI:57545 biolink:ChemicalSubstance 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57545 chebi_ph7_3 UBERON:0004521 biolink:AnatomicalEntity vasculature of muscle organ A vasculature that is part of a muscle organ [Automatically generated definition]. go-plus.json muscular organ vasculature http://purl.obolibrary.org/obo/UBERON_0004521 CHEBI:57543 biolink:ChemicalSubstance 3-(uracil-1-yl)-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57543 chebi_ph7_3 UBERON:0004522 biolink:AnatomicalEntity vasculature of musculoskeletal system A vasculature that is part of a musculoskeletal system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004522 CHEBI:57541 biolink:ChemicalSubstance 2-(alpha-D-mannosyl)-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57541 chebi_ph7_3 CHEBI:33570 biolink:ChemicalSubstance benzenediols go-plus.json http://purl.obolibrary.org/obo/CHEBI_33570 UBERON:0004520 biolink:AnatomicalEntity striated muscle tissue of prostate A portion of striated muscle tissue that is part of a prostate gland [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004520 CHEBI:57542 biolink:ChemicalSubstance aryl(methyl)malonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57542 chebi_ph7_3 CHEBI:33571 biolink:ChemicalSubstance (S)-noradrenaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_33571 UBERON:0004509 biolink:AnatomicalEntity skeletal muscle tissue of trapezius A portion of skeletal muscle tissue that is part of a trapezius [Automatically generated definition]. go-plus.json skeletal muscle tissue of trapezius muscle http://purl.obolibrary.org/obo/UBERON_0004509 CHEBI:57538 biolink:ChemicalSubstance orotidine 5'-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57538 chebi_ph7_3 CHEBI:57539 biolink:ChemicalSubstance 1D-myo-inositol 3,4,5,6-tetrakisphosphate(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57539 chebi_ph7_3 CHEBI:140922 biolink:ChemicalSubstance glioma-associated oncogene inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_140922 CHEBI:33585 biolink:ChemicalSubstance lead molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33585 CHEBI:57536 biolink:ChemicalSubstance (7R)-7-(5-carboxy-5-oxopentanamido)cephalosporanate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57536 chebi_ph7_3 UBERON:0004515 biolink:AnatomicalEntity smooth muscle tissue of bronchiole A portion of smooth muscle tissue that is part of a bronchiole [Automatically generated definition]. go-plus.json smooth muscle tissue of lobular bronchiole http://purl.obolibrary.org/obo/UBERON_0004515 CHEBI:57537 biolink:ChemicalSubstance N-acylneuraminate 9-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57537 chebi_ph7_3 CHEBI:57534 biolink:ChemicalSubstance 1-acylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57534 chebi_ph7_3 CHEBI:57535 biolink:ChemicalSubstance 4-phosphonato-L-aspartic acid(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57535 chebi_ph7_3 CHEBI:57532 biolink:ChemicalSubstance 8-amino-7-oxononanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57532 chebi_ph7_3 CHEBI:57533 biolink:ChemicalSubstance geranylgeranyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57533 chebi_ph7_3 CHEBI:33581 biolink:ChemicalSubstance boron group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33581 CHEBI:57531 biolink:ChemicalSubstance L-serine O-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57531 chebi_ph7_3 CHEBI:33582 biolink:ChemicalSubstance carbon group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33582 CHEBI:57529 biolink:ChemicalSubstance 17alpha-estradiol 3-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57529 chebi_ph7_3 CHEBI:57527 biolink:ChemicalSubstance GDP-alpha-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57527 chebi_ph7_3 CHEBI:57528 biolink:ChemicalSubstance 5-hydroxy-6-methylpyridine-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57528 chebi_ph7_3 CHEBI:33558 biolink:ChemicalSubstance alpha-amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33558 CHEBI:33559 biolink:ChemicalSubstance s-block element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33559 CHEBI:33551 biolink:ChemicalSubstance organosulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33551 CHEBI:33552 biolink:ChemicalSubstance sulfonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33552 UBERON:0004581 biolink:AnatomicalEntity systemic venous system The part of the venous system that drains the general body tissues[Kardong] go-plus.json systemic venous circulatory system http://purl.obolibrary.org/obo/UBERON_0004581 UBERON:0004582 biolink:AnatomicalEntity venous system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. go-plus.json vein system http://purl.obolibrary.org/obo/UBERON_0004582 CHEBI:33554 biolink:ChemicalSubstance organosulfonate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33554 chebi_ph7_3 CHEBI:33555 biolink:ChemicalSubstance arenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33555 CHEBI:33557 biolink:ChemicalSubstance aminobenzenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33557 CHEBI:57525 biolink:ChemicalSubstance dolichyl beta-D-glucosyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57525 chebi_ph7_3 CHEBI:57526 biolink:ChemicalSubstance N(6)-(dimethylallyl)adenosine 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57526 chebi_ph7_3 CHEBI:57523 biolink:ChemicalSubstance dolichyl D-mannosyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57523 chebi_ph7_3 CHEBI:57524 biolink:ChemicalSubstance O-phosphonato-L-serine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57524 chebi_ph7_3 CHEBI:57521 biolink:ChemicalSubstance beta-L-arabinose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57521 chebi_ph7_3 CHEBI:57522 biolink:ChemicalSubstance 12-dehydrotetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57522 chebi_ph7_3 NCBITaxon:2304100 biolink:OrganismalEntity Viteae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2304100 CHEBI:57520 biolink:ChemicalSubstance D-octopine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57520 chebi_ph7_3 CHEBI:57518 biolink:ChemicalSubstance 1-palmitoyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57518 chebi_ph7_3 CHEBI:57519 biolink:ChemicalSubstance alpha,beta-didehydrotryptophanate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57519 CHEBI:57516 biolink:ChemicalSubstance deoxylimononate D-ring-lactone(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57516 chebi_ph7_3 CHEBI:33569 biolink:ChemicalSubstance noradrenaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_33569 CHEBI:595389 biolink:ChemicalSubstance 4'-demethylrebeccamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_595389 chebi_ph7_3 UBERON:0004572 biolink:AnatomicalEntity arterial system The part of the cardiovascular system consisting of all arteries. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004572 CHEBI:33561 biolink:ChemicalSubstance d-block element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33561 UBERON:0004573 biolink:AnatomicalEntity systemic artery An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart. go-plus.json systemic arterial subtree http://purl.obolibrary.org/obo/UBERON_0004573 CHEBI:33563 biolink:ChemicalSubstance glycolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33563 UBERON:0004571 biolink:AnatomicalEntity systemic arterial system The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart. go-plus.json systemic arterial circulatory system http://purl.obolibrary.org/obo/UBERON_0004571 CHEBI:33564 biolink:ChemicalSubstance dihydroxybenzenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33564 CHEBI:33565 biolink:ChemicalSubstance 2,3-dihydroxybenzenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33565 chebi_ph7_3 CHEBI:33566 biolink:ChemicalSubstance catechols go-plus.json http://purl.obolibrary.org/obo/CHEBI_33566 chebi_ph7_3 CHEBI:33567 biolink:ChemicalSubstance catecholamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_33567 CHEBI:33568 biolink:ChemicalSubstance adrenaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_33568 CHEBI:57514 biolink:ChemicalSubstance 1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57514 chebi_ph7_3 CHEBI:57515 biolink:ChemicalSubstance 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57515 chebi_ph7_3 CHEBI:57512 biolink:ChemicalSubstance N-acyl-D-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57512 chebi_ph7_3 CHEBI:57513 biolink:ChemicalSubstance N-acetyl-D-glucosamine 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57513 chebi_ph7_3 CHEBI:57510 biolink:ChemicalSubstance dTDP-6-deoxy-beta-L-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57510 chebi_ph7_3 CHEBI:57511 biolink:ChemicalSubstance cephalosporin C(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57511 chebi_ph7_3 CHEBI:33560 biolink:ChemicalSubstance p-block element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33560 CHEBI:57509 biolink:ChemicalSubstance L-dopachromate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57509 chebi_ph7_3 CHEBI:57508 biolink:ChemicalSubstance D-erythritol 4-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57508 chebi_ph7_3 CHEBI:57505 biolink:ChemicalSubstance N-benzoyl-D-argininium-4-nitroanilide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57505 chebi_ph7_3 CHEBI:57506 biolink:ChemicalSubstance 3,5-diiodo-L-tyrosinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57506 chebi_ph7_3 PATO:0002007 biolink:OntologyClass convex 3-D shape A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave. go-plus.json http://purl.obolibrary.org/obo/PATO_0002007 CHEBI:33539 biolink:ChemicalSubstance hydroxidodioxidosulfidosulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33539 PATO:0002006 biolink:OntologyClass 2-D shape A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity. go-plus.json 2-D projection|cross-sectional http://purl.obolibrary.org/obo/PATO_0002006 CHEBI:33530 biolink:ChemicalSubstance altronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33530 CHEBI:33532 biolink:ChemicalSubstance altronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33532 CHEBI:33535 biolink:ChemicalSubstance sulfur hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_33535 CHEBI:57503 biolink:ChemicalSubstance anthocyanidin 3,5-di-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57503 chebi_ph7_3 CHEBI:57504 biolink:ChemicalSubstance L-dopa zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57504 chebi_ph7_3 CHEBI:57501 biolink:ChemicalSubstance (S)-4-amino-5-oxopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57501 chebi_ph7_3 CHEBI:57502 biolink:ChemicalSubstance nicotinate D-ribonucleotide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57502 chebi_ph7_3 UBERON:0004549 biolink:AnatomicalEntity right eye An eye that is part of a right side of organism [Automatically generated definition]. go-plus.json right orbital part of face|right eyeball|right orbital region http://purl.obolibrary.org/obo/UBERON_0004549 CHEBI:33549 biolink:ChemicalSubstance uronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33549 CHEBI:33540 biolink:ChemicalSubstance thiosulfuric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33540 CHEBI:33541 biolink:ChemicalSubstance thiosulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33541 CHEBI:33542 biolink:ChemicalSubstance trioxidosulfanidosulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33542 chebi_ph7_3 CHEBI:33543 biolink:ChemicalSubstance sulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33543 chebi_ph7_3 CHEBI:33544 biolink:ChemicalSubstance alpha-amino-acid radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_33544 UBERON:0004554 biolink:AnatomicalEntity hindlimb digital artery A digital artery that is part of a hindlimb [Automatically generated definition]. go-plus.json hindlimb digital arteries|digital artery of foot http://purl.obolibrary.org/obo/UBERON_0004554 UBERON:0004552 biolink:AnatomicalEntity digital artery An artery that is part of a digit [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004552 UBERON:0004553 biolink:AnatomicalEntity forelimb digital artery A digital artery that is part of a forelimb [Automatically generated definition]. go-plus.json forelimb digital arteries|digital artery of manus|wing digital artery http://purl.obolibrary.org/obo/UBERON_0004553 GO:0030019 biolink:MolecularActivity obsolete tryptase activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin. go-plus.json tryptase activity|rat mast cell protease II|mast cell proteinase II|mast cell serine proteinase tryptase activity|mast cell neutral proteinase activity|mast cell tryptase activity|pituitary tryptase activity|lung tryptase activity|mast cell serine proteinase II|skin tryptase activity|mast cell protease II activity|tryptase M http://purl.obolibrary.org/obo/GO_0030019 GO:0030017 biolink:CellularComponent sarcomere The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. Wikipedia:Sarcomere go-plus.json http://purl.obolibrary.org/obo/GO_0030017 GO:0030018 biolink:CellularComponent Z disc Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. go-plus.json Z band|Z line|Z disk http://purl.obolibrary.org/obo/GO_0030018 GO:0030015 biolink:CellularComponent CCR4-NOT core complex The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p. go-plus.json http://purl.obolibrary.org/obo/GO_0030015 GO:0030016 biolink:CellularComponent myofibril The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. Wikipedia:Myofibril go-plus.json http://purl.obolibrary.org/obo/GO_0030016 GO:0005057 biolink:MolecularActivity obsolete signal transducer activity, downstream of receptor OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell. go-plus.json receptor signalling protein activity|intracellular signal transducer activity|receptor signaling protein activity http://purl.obolibrary.org/obo/GO_0005057 GO:0044665 biolink:CellularComponent MLL1/2 complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species. go-plus.json Trx-containing complex http://purl.obolibrary.org/obo/GO_0044665 GO:0044666 biolink:CellularComponent MLL3/4 complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species. go-plus.json Trr/COMPASS-like complex http://purl.obolibrary.org/obo/GO_0044666 GO:0044663 biolink:BiologicalProcess establishment or maintenance of cell type involved in phenotypic switching A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. go-plus.json http://purl.obolibrary.org/obo/GO_0044663 GO:0005055 biolink:MolecularActivity laminin receptor activity Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0005055 GO:0044664 biolink:BiologicalProcess obsolete reversion of cell type to default state involved in phenotypic switching OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. go-plus.json http://purl.obolibrary.org/obo/GO_0044664 GO:0005056 biolink:MolecularActivity tiggrin receptor activity Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0005056 GO:0005053 biolink:MolecularActivity peroxisome matrix targeting signal-2 binding Binding to a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F). go-plus.json peroxisome targeting signal-2 binding|PTS2 binding|peroxisome targeting signal-2 receptor|PEX7|PTS2 receptor|peroxisomal targeting signal 2 (PTS2) binding http://purl.obolibrary.org/obo/GO_0005053 GO:0044661 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044661 GO:0005054 biolink:MolecularActivity obsolete peroxisome integral membrane receptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json Pas20p|peroxisome integral membrane receptor http://purl.obolibrary.org/obo/GO_0005054 GO:0044662 biolink:BiologicalProcess disruption by virus of host cell membrane A process by which a virus has a negative effect on the functioning of a host cellular membrane. go-plus.json disruption by organism of host cell membrane|disruption by virus of host cell membrane http://purl.obolibrary.org/obo/GO_0044662 GO:0005051 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005051 GO:0044660 biolink:BiologicalProcess viral release by cytolysis via pore formation in host cell membrane The killing by a virus of a cell in its host organism by cytolysis, caused by the formation by the virus of pores in its host cell membrane. go-plus.json cytolysis by virus via pore formation in host cell membrane|viral exit by cytolysis via pore formation in host cell membrane http://purl.obolibrary.org/obo/GO_0044660 GO:0005052 biolink:MolecularActivity peroxisome matrix targeting signal-1 binding Binding to a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L. go-plus.json peroxisome targeting signal-1 binding|PTS1 binding|PTS1 receptor|peroxisome targeting signal-1 receptor|PEX5|peroxisomal targeting signal 1 (PTS1) binding http://purl.obolibrary.org/obo/GO_0005052 GO:0005061 biolink:MolecularActivity obsolete aryl hydrocarbon receptor nuclear translocator activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json aryl hydrocarbon receptor nuclear translocator activity http://purl.obolibrary.org/obo/GO_0005061 CHEBI:140559 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_140559 chebi_ph7_3 GO:0044669 biolink:MolecularActivity sodium:galactoside symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in). go-plus.json http://purl.obolibrary.org/obo/GO_0044669 CHEBI:139558 biolink:ChemicalSubstance 1-O-(5,6-epoxyretinoyl)-beta-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139558 GO:0044667 biolink:MolecularActivity (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out). RHEA:29427 go-plus.json L-carnitine:gamma-butyrobetaine antiporter activity|L-carnitine:4-(trimethylammonio)butanoate antiporter activity|(R)-carnitine:gamma-butyrobetaine antiporter activity http://purl.obolibrary.org/obo/GO_0044667 CHEBI:139559 biolink:ChemicalSubstance (9Z,12R)-12-hydroxyoctadec-9-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139559 chebi_ph7_3 GO:0044668 biolink:MolecularActivity sodium:malonate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in). RHEA:33135 go-plus.json http://purl.obolibrary.org/obo/GO_0044668 GO:0019698 biolink:BiologicalProcess D-galacturonate catabolic process The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. MetaCyc:GALACTUROCAT-PWY go-plus.json D-galacturonate degradation|D-galacturonate breakdown|D-galacturonate catabolism http://purl.obolibrary.org/obo/GO_0019698 GO:0030013 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030013 CHEBI:139553 biolink:ChemicalSubstance 7(1)-hydroxybacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_139553 GO:0030014 biolink:CellularComponent CCR4-NOT complex The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8. go-plus.json http://purl.obolibrary.org/obo/GO_0030014 GO:0019699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019699 GO:0030011 biolink:BiologicalProcess maintenance of cell polarity The maintenance of established anisotropic intracellular organization or cell growth patterns. go-plus.json http://purl.obolibrary.org/obo/GO_0030011 GO:0019696 biolink:BiologicalProcess toluene oxidation via toluene-cis-1,2-dihydrodiol The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol. MetaCyc:TOLUENE-DEG-DIOL-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019696 CHEBI:139555 biolink:ChemicalSubstance 7(1),7(1)-dihydroxybacteriochlorophyllide d go-plus.json http://purl.obolibrary.org/obo/CHEBI_139555 GO:0019697 biolink:BiologicalProcess L-xylitol catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate. MetaCyc:LARABITOLUTIL-PWY go-plus.json L-xylitol breakdown to xylulose 5-phosphate|L-xylitol utilization|L-xylitol degradation to xylulose 5-phosphate|L-arabitol and xylitol degradation http://purl.obolibrary.org/obo/GO_0019697 GO:0030012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030012 CHEBI:139556 biolink:ChemicalSubstance EC 4.1.1.17 (ornithine decarboxylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_139556 GO:0019694 biolink:BiologicalProcess alkanesulfonate metabolic process The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. MetaCyc:ALKANEMONOX-PWY go-plus.json alkanesulphonate metabolic process|alkanesulfonate metabolism|alkanesulphonate metabolism http://purl.obolibrary.org/obo/GO_0019694 GO:0030010 biolink:BiologicalProcess establishment of cell polarity The specification and formation of anisotropic intracellular organization or cell growth patterns. go-plus.json cell polarization|bud site selection/establishment of cell polarity http://purl.obolibrary.org/obo/GO_0030010 GO:0019695 biolink:BiologicalProcess choline metabolic process The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. go-plus.json choline metabolism http://purl.obolibrary.org/obo/GO_0019695 GO:0019692 biolink:BiologicalProcess deoxyribose phosphate metabolic process The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. go-plus.json deoxyribose phosphate metabolism http://purl.obolibrary.org/obo/GO_0019692 GO:0019693 biolink:BiologicalProcess ribose phosphate metabolic process The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. go-plus.json ribose phosphate metabolism http://purl.obolibrary.org/obo/GO_0019693 GO:0030008 biolink:CellularComponent TRAPP complex A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active. Wikipedia:TRAPP_complex go-plus.json TRAPP2|TRAPP1|transport protein particle|transport protein particle complex http://purl.obolibrary.org/obo/GO_0030008 GO:0030009 biolink:MolecularActivity obsolete complement factor H activity OBSOLETE. A cofactor for the serine protease complement factor I. go-plus.json complement factor H activity http://purl.obolibrary.org/obo/GO_0030009 CHEBI:139570 biolink:ChemicalSubstance 8-formyl-8-demethylriboflavin 5'-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139570 chebi_ph7_3 GO:0030006 biolink:BiologicalProcess obsolete heavy cellular metal ion homeostasis OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. go-plus.json heavy cellular metal ion homeostasis http://purl.obolibrary.org/obo/GO_0030006 GO:0030007 biolink:BiologicalProcess cellular potassium ion homeostasis Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030007 GO:0030004 biolink:BiologicalProcess cellular monovalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030004 GO:0030005 biolink:BiologicalProcess obsolete cellular di-, tri-valent inorganic cation homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell. go-plus.json cellular di-, tri-valent inorganic cation homeostasis http://purl.obolibrary.org/obo/GO_0030005 GO:0005068 biolink:MolecularActivity transmembrane receptor protein tyrosine kinase adaptor activity The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way. go-plus.json transmembrane receptor protein tyrosine kinase adaptor protein activity|transmembrane receptor protein tyrosine kinase docking protein activity http://purl.obolibrary.org/obo/GO_0005068 GO:0044676 biolink:CellularComponent formyl-methanofuran dehydrogenase (molybdenum enzyme) complex A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0044676 GO:0044677 biolink:CellularComponent methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis. go-plus.json 5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethane sulfonate 2-methyltransferase complex|N5-methyltetrahydromethanopterin-coenzyme M methyltransferase complex|methyl-H4MPT|coenzyme M methyltransferase complex http://purl.obolibrary.org/obo/GO_0044677 GO:0005069 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005069 GO:0044674 biolink:CellularComponent methyl coenzyme M reductase complex A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0044674 GO:0005066 biolink:MolecularActivity obsolete transmembrane receptor protein tyrosine kinase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json transmembrane receptor protein tyrosine kinase signaling protein activity|transmembrane receptor protein tyrosine kinase signalling protein activity http://purl.obolibrary.org/obo/GO_0005066 GO:0044675 biolink:CellularComponent formyl-methanofuran dehydrogenase (tungsten enzyme) complex A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0044675 GO:0005067 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005067 GO:0044672 biolink:CellularComponent acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis. go-plus.json CO dehydrogenase complex|CODH/ACS complex|carbon-monoxide:(acceptor) oxidoreductase complex|carbon monoxide dehydrogenase|CO dehydrogenase/acetyl-CoA synthase complex|CODH http://purl.obolibrary.org/obo/GO_0044672 GO:0044673 biolink:CellularComponent 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420. go-plus.json FO-synthase complex http://purl.obolibrary.org/obo/GO_0044673 GO:0005065 biolink:MolecularActivity obsolete heterotrimeric G-protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json heterotrimeric G-protein http://purl.obolibrary.org/obo/GO_0005065 GO:0005062 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005062 GO:0044670 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044670 GO:0044671 biolink:BiologicalProcess sorocarp spore cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass). go-plus.json http://purl.obolibrary.org/obo/GO_0044671 GO:0005071 biolink:MolecularActivity obsolete transmembrane receptor protein serine/threonine kinase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json transmembrane receptor protein serine/threonine kinase signaling protein activity|transmembrane receptor protein serine/threonine kinase signalling protein activity http://purl.obolibrary.org/obo/GO_0005071 GO:0005072 biolink:MolecularActivity obsolete transforming growth factor beta receptor, cytoplasmic mediator activity OBSOLETE. Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus. go-plus.json TGF-beta receptor, cytoplasmic mediator activity|TGFbeta receptor, cytoplasmic mediator activity http://purl.obolibrary.org/obo/GO_0005072 GO:0005070 biolink:MolecularActivity obsolete SH3/SH2 adaptor activity OBSOLETE. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68). go-plus.json SH3/SH2 adaptor protein activity http://purl.obolibrary.org/obo/GO_0005070 CHEBI:139569 biolink:ChemicalSubstance 8-amino-8-demethylriboflavin 5'-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139569 chebi_ph7_3 GO:0044678 biolink:CellularComponent CoB-CoM heterodisulfide reductase complex A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine. go-plus.json hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex|coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex http://purl.obolibrary.org/obo/GO_0044678 GO:0044679 biolink:CellularComponent methanophenazine reducing hydrogenase complex A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides. go-plus.json http://purl.obolibrary.org/obo/GO_0044679 GO:0030002 biolink:BiologicalProcess cellular anion homeostasis Any process involved in the maintenance of an internal steady state of anions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030002 GO:0030003 biolink:BiologicalProcess cellular cation homeostasis Any process involved in the maintenance of an internal steady state of cations at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030003 CHEBI:139565 biolink:ChemicalSubstance octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139565 chebi_ph7_3 CHEBI:139567 biolink:ChemicalSubstance octadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139567 chebi_ph7_3 GO:0030001 biolink:BiologicalProcess metal ion transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json heavy metal ion transport|divalent metal ion transport http://purl.obolibrary.org/obo/GO_0030001 CHEBI:139561 biolink:ChemicalSubstance archaeal dolichyl alpha-D-glucosyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139561 chebi_ph7_3 CHEBI:139562 biolink:ChemicalSubstance archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139562 chebi_ph7_3 CHEBI:139563 biolink:ChemicalSubstance octadecatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139563 chebi_ph7_3 GO:0044680 biolink:CellularComponent methylthiol:coenzyme M methyltransferase complex A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis. go-plus.json methylthiol coenzyme M methyl transferase complex|methylthiol:coenzyme M methyl transferase complex|methylthiol:CoM methyltransferase complex http://purl.obolibrary.org/obo/GO_0044680 GO:0019680 biolink:BiologicalProcess L-methylmalonyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. MetaCyc:PWY0-43 go-plus.json L-methylmalonyl-CoA anabolism|L-methylmalonyl-CoA synthesis|L-methylmalonyl-CoA formation|L-methylmalonyl-CoA biosynthesis http://purl.obolibrary.org/obo/GO_0019680 GO:0005039 biolink:MolecularActivity obsolete death receptor-associated factor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json death receptor-associated factor activity http://purl.obolibrary.org/obo/GO_0005039 GO:0005037 biolink:MolecularActivity obsolete death receptor adaptor protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json death receptor adaptor protein activity http://purl.obolibrary.org/obo/GO_0005037 GO:0005038 biolink:MolecularActivity obsolete death receptor interacting protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json death receptor interacting protein activity http://purl.obolibrary.org/obo/GO_0005038 GO:0044687 biolink:MolecularActivity geranylfarnesyl diphosphate synthase activity Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate. EC:2.5.1.81|RHEA:25694|MetaCyc:RXN-8813 go-plus.json http://purl.obolibrary.org/obo/GO_0044687 GO:0005035 biolink:MolecularActivity death receptor activity Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death. go-plus.json apoptosis-activating receptor activity http://purl.obolibrary.org/obo/GO_0005035 CHEBI:140531 biolink:ChemicalSubstance GDP-6-deoxy-alpha-D-altrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_140531 CHEBI:140532 biolink:ChemicalSubstance N-arachidonoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140532 chebi_ph7_3 GO:0044688 biolink:MolecularActivity 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+. go-plus.json http://purl.obolibrary.org/obo/GO_0044688 GO:0044685 biolink:MolecularActivity tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O. EC:2.1.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0044685 GO:0005033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005033 GO:0044686 biolink:MolecularActivity cysteate synthase activity Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-. EC:2.5.1.76|RHEA:26486|MetaCyc:RXN-11108 go-plus.json http://purl.obolibrary.org/obo/GO_0044686 GO:0005034 biolink:MolecularActivity osmosensor activity Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0005034 GO:0044683 biolink:MolecularActivity methylthiol:coenzyme M methyltransferase activity Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM. RHEA:32667|EC:2.1.1.251|MetaCyc:RXN-8125 go-plus.json methylthiol:coenzyme M methyl transferase activity http://purl.obolibrary.org/obo/GO_0044683 GO:0005031 biolink:MolecularActivity tumor necrosis factor-activated receptor activity Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function. go-plus.json tumor necrosis factor receptor activity|TNF receptor activity|TNF receptor activity, type I|tumor necrosis factor receptor activity, type II|tumor necrosis factor receptor activity, type I|TNF receptor activity, type II|NGF/TNF (6 C-domain) receptor activity http://purl.obolibrary.org/obo/GO_0005031 GO:0044684 biolink:MolecularActivity dihydromethanopterin reductase activity Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP. EC:1.5.99.15|RHEA:42804 go-plus.json http://purl.obolibrary.org/obo/GO_0044684 GO:0005032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005032 GO:0044681 biolink:CellularComponent sulfopyruvate decarboxylase complex A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0044681 GO:0044682 biolink:MolecularActivity archaeal-specific GTP cyclohydrolase activity Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+. go-plus.json MptA activity|Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity http://purl.obolibrary.org/obo/GO_0044682 GO:0005030 biolink:MolecularActivity neurotrophin receptor activity Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0005030 CHEBI:139539 biolink:ChemicalSubstance (S,S)-bis-(3-oleoylglycero)-1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139539 CHEBI:140537 biolink:ChemicalSubstance diethylphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140537 chebi_ph7_3 CHEBI:140535 biolink:ChemicalSubstance TRPV1 agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_140535 CHEBI:140533 biolink:ChemicalSubstance 3-acetamido-4-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140533 chebi_ph7_3 GO:0044689 biolink:MolecularActivity 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+. MetaCyc:RXN-8079|EC:2.5.1.147|RHEA:27373 go-plus.json FO synthase http://purl.obolibrary.org/obo/GO_0044689 GO:0019678 biolink:BiologicalProcess propionate metabolic process, methylmalonyl pathway The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway. MetaCyc:PROPIONMET-PWY go-plus.json propionate metabolism, methylmalonyl pathway http://purl.obolibrary.org/obo/GO_0019678 CHEBI:140534 biolink:ChemicalSubstance 3-acetylamino-4-hydroxybenzaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140534 chebi_ph7_3 GO:0019679 biolink:BiologicalProcess propionate metabolic process, methylcitrate cycle The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle. MetaCyc:PWY0-42 go-plus.json propionate metabolism, methylcitrate cycle http://purl.obolibrary.org/obo/GO_0019679 GO:0019676 biolink:BiologicalProcess ammonia assimilation cycle The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen. MetaCyc:AMMASSIM-PWY|MetaCyc:PWY-3282 go-plus.json glutamate metabolism via glutamine and ammonia|glutamate metabolic process via glutamine and ammonia http://purl.obolibrary.org/obo/GO_0019676 GO:0019677 biolink:BiologicalProcess NAD catabolic process The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json oxidized NAD catabolic process|NAD (reduced) catabolic process|reduced NAD catabolism|NAD catabolism|reduced nicotinamide adenine dinucleotide catabolism|nicotinamide adenine dinucleotide catabolism|NAD (oxidized) catabolic process|NADH catabolism|NAD degradation|NADH catabolic process|NAD (oxidized) catabolism|nicotinamide adenine dinucleotide catabolic process|NAD breakdown|reduced nicotinamide adenine dinucleotide catabolic process|reduced NAD catabolic process|NAD (reduced) catabolism|oxidized NAD catabolism|oxidized nicotinamide adenine dinucleotide catabolic process|oxidized nicotinamide adenine dinucleotide catabolism http://purl.obolibrary.org/obo/GO_0019677 GO:0019674 biolink:BiologicalProcess NAD metabolic process The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. go-plus.json oxidized nicotinamide adenine dinucleotide metabolism|NAD (oxidized) metabolic process|NAD metabolism|nicotinamide adenine dinucleotide metabolic process|nicotinamide adenine dinucleotide metabolism|NAD (oxidized) metabolism|oxidized nicotinamide adenine dinucleotide metabolic process|oxidized NAD metabolic process|oxidized NAD metabolism|NAD phosphorylation and dephosphorylation http://purl.obolibrary.org/obo/GO_0019674 GO:0019675 biolink:BiologicalProcess obsolete NAD phosphorylation and dephosphorylation OBSOLETE. The addition or removal of a phosphate group from nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. go-plus.json nicotinamide adenine dinucleotide phosphorylation and dephosphorylation|NAD phosphorylation and dephosphorylation http://purl.obolibrary.org/obo/GO_0019675 GO:0019672 biolink:BiologicalProcess ethanol-acetate fermentation to butyrate and caproate The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0019672 GO:0019673 biolink:BiologicalProcess GDP-mannose metabolic process The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-mannose metabolism http://purl.obolibrary.org/obo/GO_0019673 GO:0019670 biolink:BiologicalProcess anaerobic glutamate catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP. go-plus.json glutamate fermentation http://purl.obolibrary.org/obo/GO_0019670 GO:0019671 biolink:BiologicalProcess glutamate catabolic process via mesaconate and citramalate The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP. MetaCyc:GLUDEG-II-PWY|MetaCyc:PWY-5088|MetaCyc:PWY-5087 go-plus.json glutamate fermentation via mesaconate and citramalate http://purl.obolibrary.org/obo/GO_0019671 GO:0019690 biolink:BiologicalProcess pyrimidine deoxyribonucleoside interconversion The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside. go-plus.json http://purl.obolibrary.org/obo/GO_0019690 GO:0044690 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044690 GO:0019691 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019691 GO:0044691 biolink:BiologicalProcess tooth eruption The tooth development process in which the teeth enter the mouth and become visible. Wikipedia:Tooth_eruption go-plus.json http://purl.obolibrary.org/obo/GO_0044691 GO:0005048 biolink:MolecularActivity signal sequence binding Binding to a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized. go-plus.json signal sequence receptor|protein signal sequence binding|leader sequence binding http://purl.obolibrary.org/obo/GO_0005048 GO:0005049 biolink:MolecularActivity nuclear export signal receptor activity Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein. go-plus.json NES receptor|importin-alpha binding|exportin activity|importin-alpha export receptor activity http://purl.obolibrary.org/obo/GO_0005049 GO:0044698 biolink:BiologicalProcess obsolete morphogenesis of symbiont in host cell OBSOLETE. The process in which a symbiont undergoes a change in shape or form, within the host's cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044698 GO:0005046 biolink:MolecularActivity KDEL sequence binding Binding to a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum. go-plus.json KDEL receptor activity http://purl.obolibrary.org/obo/GO_0005046 RO:0002022 biolink:OntologyClass directly regulated by RO:0002022 go-plus.json http://purl.obolibrary.org/obo/RO_0002022 RO:0002023 biolink:OntologyClass directly negatively regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. RO:0002023 go-plus.json http://purl.obolibrary.org/obo/RO_0002023 GO:0005047 biolink:MolecularActivity signal recognition particle binding Binding to a signal recognition particle. go-plus.json signal recognition particle receptor|docking protein http://purl.obolibrary.org/obo/GO_0005047 GO:0044699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044699 CHEBI:140521 biolink:ChemicalSubstance 13-methyltetradecenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_140521 GO:0044696 biolink:BiologicalProcess killing by virus of host cell by post-segregational killing The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes. go-plus.json killing by virus of host cell by PSK|killing by virus of host cell by toxin-antitoxin system http://purl.obolibrary.org/obo/GO_0044696 GO:0005044 biolink:MolecularActivity scavenger receptor activity Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs). go-plus.json macrophage receptor activity http://purl.obolibrary.org/obo/GO_0005044 goslim_chembl RO:0002024 biolink:OntologyClass directly positively regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. RO:0002024 go-plus.json http://purl.obolibrary.org/obo/RO_0002024 GO:0044697 biolink:CellularComponent HICS complex A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0044697 GO:0005045 biolink:MolecularActivity obsolete endoplasmic reticulum receptor activity OBSOLETE. A receptor in the endoplasmic reticulum. go-plus.json endoplasmic reticulum receptor activity http://purl.obolibrary.org/obo/GO_0005045 RO:0002025 biolink:OntologyClass has effector activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. RO:0002025 go-plus.json http://purl.obolibrary.org/obo/RO_0002025 GO:0044694 biolink:BiologicalProcess pore-mediated entry of viral genome into host cell Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail. VZ:979 go-plus.json viral genome delivery via icosahedral vertex|membrane puncture-mediated penetration of viral genome into host cell|pore-mediated penetration of viral genome into host cell|viral genome translocation|viral pore-forming protein|viral entry via genome injection http://purl.obolibrary.org/obo/GO_0044694 GO:0005042 biolink:MolecularActivity netrin receptor activity Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0005042 GO:0005043 biolink:MolecularActivity netrin receptor activity involved in chemorepulsion Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin. go-plus.json netrin receptor activity involved in negative chemotaxis|repulsive netrin receptor activity http://purl.obolibrary.org/obo/GO_0005043 GO:0044695 biolink:CellularComponent Dsc E3 ubiquitin ligase complex An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044695 GO:0044692 biolink:MolecularActivity exoribonuclease activator activity Binds to and increases the activity of an exoribonuclease. go-plus.json http://purl.obolibrary.org/obo/GO_0044692 RO:0002020 biolink:OntologyClass transports Holds between p and c when p is a transport process or transporter activity and the outcome of this p is to move c from one location to another. RO:0002020 go-plus.json http://purl.obolibrary.org/obo/RO_0002020 GO:0005040 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005040 GO:0044693 biolink:MolecularActivity trehalose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in). go-plus.json trehalose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0044693 RO:0002021 biolink:OntologyClass occurs across A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. RO:0002021 go-plus.json http://purl.obolibrary.org/obo/RO_0002021 GO:0005041 biolink:MolecularActivity low-density lipoprotein particle receptor activity Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis. Reactome:R-HSA-2424254|Reactome:R-HSA-2404131|Wikipedia:LDL_receptor go-plus.json LDL receptor|low-density lipoprotein receptor activity|LDLR activity http://purl.obolibrary.org/obo/GO_0005041 RO:0002019 biolink:OntologyClass has ligand A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function. RO:0002019 go-plus.json http://purl.obolibrary.org/obo/RO_0002019 CHEBI:57495 biolink:ChemicalSubstance 2-aminomuconate 6-semialdehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57495 CHEBI:140528 biolink:ChemicalSubstance 6-methylthioguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140528 chebi_ph7_3 GO:0005050 biolink:MolecularActivity obsolete peroxisome receptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json peroxisome receptor http://purl.obolibrary.org/obo/GO_0005050 CHEBI:57496 biolink:ChemicalSubstance 3-carboxy-cis,cis-muconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57496 chebi_ph7_3 CHEBI:57493 biolink:ChemicalSubstance pseudotropinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57493 chebi_ph7_3 CHEBI:140526 biolink:ChemicalSubstance 1,2-dihexanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_140526 chebi_ph7_3 CHEBI:140527 biolink:ChemicalSubstance 1,2-dihexanoyl-3-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_140527 chebi_ph7_3 RO:0002015 biolink:OntologyClass has positive regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. RO:0002015 go-plus.json http://purl.obolibrary.org/obo/RO_0002015 CHEBI:57491 biolink:ChemicalSubstance staurosporinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57491 chebi_ph7_3 CHEBI:57492 biolink:ChemicalSubstance isopropylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57492 chebi_ph7_3 CHEBI:140525 biolink:ChemicalSubstance sn-1,2-diricinolein go-plus.json http://purl.obolibrary.org/obo/CHEBI_140525 chebi_ph7_3 RO:0002016 biolink:OntologyClass has necessary component activity RO:0002016 go-plus.json http://purl.obolibrary.org/obo/RO_0002016 GO:0019689 biolink:BiologicalProcess pyrimidine nucleoside interconversion The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside. go-plus.json http://purl.obolibrary.org/obo/GO_0019689 CHEBI:140522 biolink:ChemicalSubstance [(1->4)-alpha-D-galacturonosyl methyl ester](n) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140522 chebi_ph7_3 RO:0002017 biolink:OntologyClass has component activity RO:0002017 go-plus.json http://purl.obolibrary.org/obo/RO_0002017 RO:0002018 biolink:OntologyClass has component process w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. RO:0002018 go-plus.json http://purl.obolibrary.org/obo/RO_0002018 CHEBI:57490 biolink:ChemicalSubstance N-carbamoylsarcosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57490 chebi_ph7_3 CHEBI:140523 biolink:ChemicalSubstance [(1->4)-alpha-D-galacturonosyl](n) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140523 chebi_ph7_3 GO:0019687 biolink:BiologicalProcess pyruvate biosynthetic process from acetate The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate. go-plus.json pyruvate synthesis from acetate|pyruvate anabolism from acetate|pyruvate formation from acetate http://purl.obolibrary.org/obo/GO_0019687 GO:0019688 biolink:BiologicalProcess purine deoxyribonucleoside interconversion The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside. go-plus.json http://purl.obolibrary.org/obo/GO_0019688 CHEBI:139543 biolink:ChemicalSubstance (S,S)-2-oleoylglycero-1-phospho-1'-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_139543 GO:0019685 biolink:BiologicalProcess photosynthesis, dark reaction A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions. go-plus.json http://purl.obolibrary.org/obo/GO_0019685 GO:0019686 biolink:BiologicalProcess purine nucleoside interconversion The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside. go-plus.json http://purl.obolibrary.org/obo/GO_0019686 GO:0019683 biolink:BiologicalProcess glyceraldehyde-3-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis. go-plus.json glyceraldehyde-3-phosphate catabolism|glyceraldehyde 3-phosphate catabolic process|glyceraldehyde-3-phosphate degradation|glyceraldehyde-3-phosphate breakdown|glyceraldehyde 3-phosphate catabolism http://purl.obolibrary.org/obo/GO_0019683 CHEBI:57499 biolink:ChemicalSubstance 2-oxoadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57499 chebi_ph7_3 GO:0019684 biolink:BiologicalProcess photosynthesis, light reaction The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I. MetaCyc:PWY-101|Wikipedia:Photolysis#Photolysis_in_photosynthesis go-plus.json photolysis http://purl.obolibrary.org/obo/GO_0019684 CHEBI:139540 biolink:ChemicalSubstance (S,S)-3-oleoylglycero-1-phospho-1'-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_139540 CHEBI:57497 biolink:ChemicalSubstance dolichyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57497 chebi_ph7_3 GO:0019681 biolink:BiologicalProcess acetyl-CoA assimilation pathway The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell. go-plus.json acetyl-CoA catabolic process to alpha-ketoglutarate|acetyl-CoA catabolism to 2-ketoglutarate|acetyl-CoA catabolic process to 2-oxoglutarate|acetyl-CoA catabolic process to 2-ketoglutarate|acetyl-CoA catabolism to 2-oxoglutarate|acetyl-CoA catabolic process to alpha-oxoglutarate|acetyl-CoA catabolism to alpha-ketoglutarate|acetyl-CoA catabolism to alpha-oxoglutarate http://purl.obolibrary.org/obo/GO_0019681 GO:0019682 biolink:BiologicalProcess glyceraldehyde-3-phosphate metabolic process The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis. go-plus.json glyceraldehyde 3-phosphate metabolism|glyceraldehyde 3-phosphate metabolic process|glyceraldehyde-3-phosphate metabolism http://purl.obolibrary.org/obo/GO_0019682 CHEBI:57498 biolink:ChemicalSubstance ADP alpha-D-glucoside(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57498 chebi_ph7_3 CHEBI:139541 biolink:ChemicalSubstance (S,S)-bis(2-oleoylglycero)-1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139541 GO:0005019 biolink:MolecularActivity platelet-derived growth factor beta-receptor activity Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity. go-plus.json PDGF beta-receptor activity|betaPDGF receptor activity http://purl.obolibrary.org/obo/GO_0005019 GO:0005017 biolink:MolecularActivity platelet-derived growth factor-activated receptor activity Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json platelet-derived growth factor receptor activity|PDGFR activity|PDGF-activated receptor activity|PDGF receptor activity http://purl.obolibrary.org/obo/GO_0005017 GO:0005018 biolink:MolecularActivity platelet-derived growth factor alpha-receptor activity Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity. go-plus.json PDGF alpha-receptor activity|alphaPDGF receptor activity http://purl.obolibrary.org/obo/GO_0005018 GO:0005015 biolink:MolecularActivity obsolete neurotrophin TRKB receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json neurotrophin TRKB receptor activity http://purl.obolibrary.org/obo/GO_0005015 GO:0005016 biolink:MolecularActivity obsolete neurotrophin TRKC receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json neurotrophin TRKC receptor activity http://purl.obolibrary.org/obo/GO_0005016 GO:0005013 biolink:MolecularActivity obsolete neurotrophin TRK receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json neurotrophin TRK receptor activity http://purl.obolibrary.org/obo/GO_0005013 RO:0002011 biolink:OntologyClass regulates transport of A relationship that holds between a process that regulates a transport process and the entity transported by that process. RO:0002011 go-plus.json http://purl.obolibrary.org/obo/RO_0002011 GO:0005014 biolink:MolecularActivity obsolete neurotrophin TRKA receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json neurotrophin TRKA receptor activity http://purl.obolibrary.org/obo/GO_0005014 GO:0005011 biolink:MolecularActivity macrophage colony-stimulating factor receptor activity Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. go-plus.json Fms|macrophage colony stimulating factor receptor activity|CSF-1|M-CSF receptor activity http://purl.obolibrary.org/obo/GO_0005011 RO:0002013 biolink:OntologyClass has regulatory component activity A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. RO:0002013 go-plus.json http://purl.obolibrary.org/obo/RO_0002013 RO:0002014 biolink:OntologyClass has negative regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. RO:0002014 go-plus.json http://purl.obolibrary.org/obo/RO_0002014 GO:0005012 biolink:MolecularActivity obsolete Neu/ErbB-2 receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json Neu/ErbB-2 receptor activity http://purl.obolibrary.org/obo/GO_0005012 GO:0005010 biolink:MolecularActivity insulin-like growth factor-activated receptor activity Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json IGF-activated receptor activity|IGF receptor activity|insulin-like growth factor receptor activity http://purl.obolibrary.org/obo/GO_0005010 RO:0002008 biolink:OntologyClass coincident with A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other. RO:0002008 go-plus.json http://purl.obolibrary.org/obo/RO_0002008 CHEBI:57484 biolink:ChemicalSubstance trimethylenediaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57484 chebi_ph7_3 CHEBI:57485 biolink:ChemicalSubstance carnosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57485 chebi_ph7_3 CHEBI:139518 biolink:ChemicalSubstance (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine dimer(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139518 chebi_ph7_3 CHEBI:57482 biolink:ChemicalSubstance streptomycin 3''-phosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57482 chebi_ph7_3 CHEBI:140515 biolink:ChemicalSubstance 6-chloro-D-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_140515 CHEBI:139519 biolink:ChemicalSubstance thymidine dimer(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139519 chebi_ph7_3 CHEBI:140516 biolink:ChemicalSubstance 6-chlorotryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_140516 CHEBI:57483 biolink:ChemicalSubstance sedoheptulose 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57483 chebi_ph7_3 GO:0019658 biolink:BiologicalProcess glucose fermentation to lactate and acetate The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP. MetaCyc:P124-PWY go-plus.json bifidum pathway|glucose catabolic process to lactate and acetate http://purl.obolibrary.org/obo/GO_0019658 CHEBI:57480 biolink:ChemicalSubstance 2,3-dihydrobiochanin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57480 CHEBI:139513 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139513 chebi_ph7_3 GO:0019659 biolink:BiologicalProcess glucose catabolic process to lactate The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP). Wikipedia:Lactic_acid_fermentation go-plus.json lactate fermentation|glucose fermentation to lactate http://purl.obolibrary.org/obo/GO_0019659 RO:0002005 biolink:OntologyClass RO:0002005 go-plus.json nerve supply http://purl.obolibrary.org/obo/RO_0002005 CHEBI:57481 biolink:ChemicalSubstance UTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57481 CHEBI:139514 biolink:ChemicalSubstance nonaflavuxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139514 chebi_ph7_3 GO:0019656 biolink:BiologicalProcess glucose catabolic process to D-lactate and ethanol The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule. MetaCyc:P122-PWY go-plus.json heterolactate fermentation|glucose fermentation to D-lactate and ethanol|heterolactic fermentation|heterofermentative lactate fermentation|heterofermentation|heterofermentative pathway http://purl.obolibrary.org/obo/GO_0019656 CHEBI:139515 biolink:ChemicalSubstance flavuxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139515 chebi_ph7_3 RO:0002007 biolink:OntologyClass bounding layer of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 RO:0002007 go-plus.json http://purl.obolibrary.org/obo/RO_0002007 GO:0019657 biolink:BiologicalProcess glycolytic fermentation to propionate Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate. MetaCyc:P108-PWY go-plus.json succinate-propionate fermentation http://purl.obolibrary.org/obo/GO_0019657 GO:0019654 biolink:BiologicalProcess acetate fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP. MetaCyc:P142-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019654 GO:0019655 biolink:BiologicalProcess glycolytic fermentation to ethanol The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose. Wikipedia:Ethanol_fermentation go-plus.json alcoholic fermentation|ethanol fermentation|glucose catabolic process to ethanol|glucose fermentation to ethanol http://purl.obolibrary.org/obo/GO_0019655 CHEBI:139510 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139510 chebi_ph7_3 GO:0019652 biolink:BiologicalProcess lactate fermentation to propionate and acetate The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP). MetaCyc:PROPFERM-PWY go-plus.json acrylate pathway|propionate fermentation|nonrandomizing pathway http://purl.obolibrary.org/obo/GO_0019652 CHEBI:139511 biolink:ChemicalSubstance reduced coenzyme F420-(gamma-Glu)n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139511 chebi_ph7_3 GO:0019653 biolink:BiologicalProcess anaerobic purine nucleobase catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP. MetaCyc:P164-PWY|MetaCyc:PWY-5497|MetaCyc:PWY-5044 go-plus.json anaerobic purine base catabolism|anaerobic purine catabolic process|purine fermentation|anaerobic purine base catabolic process|purine base fermentation http://purl.obolibrary.org/obo/GO_0019653 GO:0019650 biolink:BiologicalProcess glycolytic fermentation to butanediol The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia. MetaCyc:P125-PWY|Wikipedia:Butanediol_fermentation go-plus.json glucose catabolic process to butanediol|glucose fermentation to butanediol|butanediol fermentation http://purl.obolibrary.org/obo/GO_0019650 CHEBI:57488 biolink:ChemicalSubstance hydrogen phosphonatoacetate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57488 chebi_ph7_3 GO:0019651 biolink:BiologicalProcess citrate catabolic process to diacetyl The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP. go-plus.json diacetyl fermentation|citrate fermentation to diacetyl http://purl.obolibrary.org/obo/GO_0019651 CHEBI:57486 biolink:ChemicalSubstance 4-guanidinobutanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57486 chebi_ph7_3 CHEBI:57487 biolink:ChemicalSubstance pyruvate oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_57487 chebi_ph7_3 GO:0005028 biolink:MolecularActivity obsolete CD40 receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json CD40 receptor activity http://purl.obolibrary.org/obo/GO_0005028 GO:0005029 biolink:MolecularActivity obsolete CD27 receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json CD27 receptor activity http://purl.obolibrary.org/obo/GO_0005029 GO:0005026 biolink:MolecularActivity transforming growth factor beta receptor activity, type II Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor. Reactome:R-HSA-170843 go-plus.json type II TGFbeta receptor activity|type II TGF-beta receptor activity|transforming growth factor beta ligand binding to type II receptor|type II transforming growth factor beta receptor activity http://purl.obolibrary.org/obo/GO_0005026 GO:0005027 biolink:MolecularActivity obsolete NGF/TNF (6 C-domain) receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json NGF/TNF (6 C-domain) receptor activity http://purl.obolibrary.org/obo/GO_0005027 GO:0005024 biolink:MolecularActivity transforming growth factor beta-activated receptor activity Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. go-plus.json TGF-beta receptor activity|TGFbeta-activated receptor activity|TGFbeta receptor activity|TGFbetaR|transforming growth factor beta receptor activity http://purl.obolibrary.org/obo/GO_0005024 GO:0005025 biolink:MolecularActivity transforming growth factor beta receptor activity, type I Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals. go-plus.json type I TGF-beta receptor activity|type I TGFbeta receptor activity|transforming growth factor beta ligand binding to type I receptor|type I transforming growth factor beta receptor activity http://purl.obolibrary.org/obo/GO_0005025 RO:0002002 biolink:OntologyClass RO:0002002 go-plus.json http://purl.obolibrary.org/obo/RO_0002002 GO:0005023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005023 GO:0005020 biolink:MolecularActivity stem cell factor receptor activity Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation. go-plus.json KL receptor activity|KIT|KIT ligand receptor activity|SCF receptor activity http://purl.obolibrary.org/obo/GO_0005020 GO:0005021 biolink:MolecularActivity vascular endothelial growth factor-activated receptor activity Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json VEGF-D-activated receptor activity|VEGF-C-activated receptor activity|VEGF receptor activity|VEGF-B-activated receptor activity|VEGF-A-activated receptor activity|vascular endothelial growth factor E-activated receptor activity|VEGFR activity|VEGF-activated receptor activity|vascular endothelial growth factor receptor activity|VEGF-E-activated receptor activity http://purl.obolibrary.org/obo/GO_0005021 CHEBI:57473 biolink:ChemicalSubstance 3'-demethylstaurosporinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57473 chebi_ph7_3 CHEBI:57474 biolink:ChemicalSubstance (R)-S-lactoylglutathionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57474 chebi_ph7_3 CHEBI:139529 biolink:ChemicalSubstance inositol phosphomannosylinositol-1-phospho-N-acylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139529 CHEBI:57471 biolink:ChemicalSubstance (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57471 chebi_ph7_3 CHEBI:57472 biolink:ChemicalSubstance (N(omega)-L-arginino)succinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57472 chebi_ph7_3 GO:0019669 biolink:BiologicalProcess anaerobic glycine catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP. go-plus.json glycine fermentation http://purl.obolibrary.org/obo/GO_0019669 CHEBI:57470 biolink:ChemicalSubstance (2E)-3-(methoxycarbonyl)pent-2-enedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57470 chebi_ph7_3 GO:0019667 biolink:BiologicalProcess anaerobic L-alanine catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP. go-plus.json L-alanine fermentation http://purl.obolibrary.org/obo/GO_0019667 GO:0019668 biolink:BiologicalProcess anaerobic catabolism of pairs of amino acids The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP. go-plus.json Stickland reaction|cofermentation of pairs of amino acids http://purl.obolibrary.org/obo/GO_0019668 GO:0019665 biolink:BiologicalProcess anaerobic amino acid catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP. go-plus.json amino acid fermentation http://purl.obolibrary.org/obo/GO_0019665 CHEBI:139520 biolink:ChemicalSubstance phenolic donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_139520 chebi_ph7_3 GO:0019666 biolink:BiologicalProcess nitrogenous compound fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP. go-plus.json nitrogenous compound catabolic process http://purl.obolibrary.org/obo/GO_0019666 CHEBI:139521 biolink:ChemicalSubstance phenolic radical donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_139521 chebi_ph7_3 GO:0019663 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019663 CHEBI:57479 biolink:ChemicalSubstance 2,6-dioxo-6-phenylhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57479 chebi_ph7_3 GO:0019664 biolink:BiologicalProcess mixed acid fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP. Wikipedia:Mixed_acid_fermentation go-plus.json glucose catabolic process to mixed acids|glucose fermentation to mixed acids http://purl.obolibrary.org/obo/GO_0019664 GO:0019661 biolink:BiologicalProcess glucose catabolic process to lactate via pyruvate The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP). MetaCyc:ANAEROFRUCAT-PWY go-plus.json homofermentation|glucose fermentation to lactate via pyruvate|homolactic fermentation|homofermentative pathway|homolactate fermentation|homofermentative lactate fermentation http://purl.obolibrary.org/obo/GO_0019661 CHEBI:57477 biolink:ChemicalSubstance dTDP-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57477 chebi_ph7_3 GO:0019662 biolink:BiologicalProcess non-glycolytic fermentation Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0019662 CHEBI:57478 biolink:ChemicalSubstance alpha-maltose 6'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57478 chebi_ph7_3 CHEBI:57475 biolink:ChemicalSubstance D-4-hydroxyphenylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57475 chebi_ph7_3 CHEBI:57476 biolink:ChemicalSubstance L-homoserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57476 chebi_ph7_3 GO:0019660 biolink:BiologicalProcess glycolytic fermentation Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway. MetaCyc:Pyruvate-Degredation go-plus.json http://purl.obolibrary.org/obo/GO_0019660 CHEBI:140509 biolink:ChemicalSubstance 6-chloro-D-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140509 chebi_ph7_3 CHEBI:57462 biolink:ChemicalSubstance leukotriene E4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57462 chebi_ph7_3 CHEBI:57463 biolink:ChemicalSubstance leukotriene A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57463 chebi_ph7_3 CHEBI:57460 biolink:ChemicalSubstance 20-hydroxy-leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57460 chebi_ph7_3 CHEBI:33497 biolink:ChemicalSubstance transition element molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33497 GO:0019638 biolink:BiologicalProcess 6-hydroxycineole metabolic process The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2. go-plus.json 6-endo-hydroxycineole metabolic process|hydroxycineol metabolism|6-hydroxycineole metabolism|hydroxycineol metabolic process|6-endo-hydroxycineole metabolism http://purl.obolibrary.org/obo/GO_0019638 GO:0019639 biolink:BiologicalProcess 6-hydroxycineole catabolic process The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2. MetaCyc:6-HYDROXYCINEOLE-DEGRADATION-PWY go-plus.json hydroxycineol catabolic process|hydroxycineol catabolism|6-hydroxycineole catabolism|6-endo-hydroxycineole catabolic process|6-hydroxycineole degradation|6-endo-hydroxycineole catabolism|6-hydroxycineole breakdown http://purl.obolibrary.org/obo/GO_0019639 CHEBI:57461 biolink:ChemicalSubstance leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57461 chebi_ph7_3 GO:0019636 biolink:BiologicalProcess phosphonoacetate metabolic process The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue. MetaCyc:P483-PWY go-plus.json phosphonoacetate metabolism http://purl.obolibrary.org/obo/GO_0019636 GO:0019637 biolink:BiologicalProcess organophosphate metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound. go-plus.json organophosphate metabolism http://purl.obolibrary.org/obo/GO_0019637 GO:0019634 biolink:BiologicalProcess organic phosphonate metabolic process The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. go-plus.json organophosphonate metabolic process|phosphonate metabolism http://purl.obolibrary.org/obo/GO_0019634 GO:0019635 biolink:BiologicalProcess 2-aminoethylphosphonate catabolic process The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine. MetaCyc:PHOSPHONOTASE-PWY go-plus.json ciliatine catabolic process|2-phosphonoethylamine catabolic process|2-phosphonoethylamine catabolism|ciliatine catabolism|2-aminoethylphosphonate degradation|2-aminoethylphosphonate catabolism|2-aminoethylphosphonate breakdown http://purl.obolibrary.org/obo/GO_0019635 GO:0019632 biolink:BiologicalProcess shikimate metabolic process The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids. go-plus.json shikimate metabolism http://purl.obolibrary.org/obo/GO_0019632 GO:0019633 biolink:BiologicalProcess shikimate catabolic process The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. MetaCyc:SHIKIMATEDEG-PWY go-plus.json shikimate degradation|shikimate catabolism|shikimate breakdown http://purl.obolibrary.org/obo/GO_0019633 CHEBI:57468 biolink:ChemicalSubstance 7(S),8(S)-DiHODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57468 chebi_ph7_3 GO:0019630 biolink:BiologicalProcess quinate metabolic process The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine. go-plus.json quinate metabolism|quinic acid metabolic process|quinic acid metabolism http://purl.obolibrary.org/obo/GO_0019630 GO:0019631 biolink:BiologicalProcess quinate catabolic process The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid. MetaCyc:QUINATEDEG-PWY go-plus.json quinate catabolism|quinic acid catabolic process|quinic acid catabolism|quinate degradation|quinate breakdown http://purl.obolibrary.org/obo/GO_0019631 CHEBI:57469 biolink:ChemicalSubstance (2E)-2-(methoxycarbonylmethyl)but-2-enedioate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57469 chebi_ph7_3 CHEBI:33490 biolink:ChemicalSubstance hydrogenselenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33490 CHEBI:57466 biolink:ChemicalSubstance 13(S)-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57466 chebi_ph7_3 CHEBI:57467 biolink:ChemicalSubstance (11S)-11-hydroperoxylinoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57467 chebi_ph7_3 CHEBI:57464 biolink:ChemicalSubstance 5'-xanthylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57464 chebi_ph7_3 GO:0005008 biolink:MolecularActivity hepatocyte growth factor-activated receptor activity Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json HGF-activated receptor activity|HGF receptor activity|hepatocyte growth factor receptor activity http://purl.obolibrary.org/obo/GO_0005008 GO:0005009 biolink:MolecularActivity insulin-activated receptor activity Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json insulin receptor activity http://purl.obolibrary.org/obo/GO_0005009 GO:0005006 biolink:MolecularActivity epidermal growth factor-activated receptor activity Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json epidermal growth factor receptor activity|transforming growth factor-alpha receptor activity|TGF-alpha receptor activity|EGF receptor activity|EGFR http://purl.obolibrary.org/obo/GO_0005006 GO:0005007 biolink:MolecularActivity fibroblast growth factor-activated receptor activity Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json FGF-activated receptor activity|fibroblast growth factor receptor activity|FGF receptor activity|FGFR http://purl.obolibrary.org/obo/GO_0005007 GO:0005004 biolink:MolecularActivity GPI-linked ephrin receptor activity Combining with a GPI-anchored ephrin to initiate a change in cell activity. go-plus.json GPI-linked Eph receptor activity http://purl.obolibrary.org/obo/GO_0005004 GO:0005005 biolink:MolecularActivity transmembrane-ephrin receptor activity Combining with a transmembrane ephrin to initiate a change in cell activity. go-plus.json transmembrane-Eph receptor activity http://purl.obolibrary.org/obo/GO_0005005 GO:0005003 biolink:MolecularActivity ephrin receptor activity Combining with an ephrin to initiate a change in cell activity. go-plus.json Eph receptor activity http://purl.obolibrary.org/obo/GO_0005003 GO:0005000 biolink:MolecularActivity vasopressin receptor activity Combining with vasopressin to initiate a change in cell activity. go-plus.json vasopressin activated calcium mobilizing receptor activity http://purl.obolibrary.org/obo/GO_0005000 GO:0005001 biolink:MolecularActivity transmembrane receptor protein tyrosine phosphatase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0005001 CHEBI:57451 biolink:ChemicalSubstance dihydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57451 chebi_ph7_3 CHEBI:139506 biolink:ChemicalSubstance N(5)-phospho-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139506 CHEBI:139507 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139507 chebi_ph7_3 CHEBI:57452 biolink:ChemicalSubstance 10-formyldihydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57452 chebi_ph7_3 GO:0019649 biolink:BiologicalProcess formaldehyde assimilation The pathways in which formaldehyde is processed and used as a carbon source for the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0019649 CHEBI:139508 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_139508 chebi_ph7_3 CHEBI:57450 biolink:ChemicalSubstance 5(S)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57450 chebi_ph7_3 CHEBI:139509 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139509 chebi_ph7_3 GO:0019647 biolink:BiologicalProcess formaldehyde assimilation via ribulose monophosphate cycle The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde. MetaCyc:PWY-1861 go-plus.json ribulose monophosphate cycle|formaldehyde assimilation via RuMP cycle http://purl.obolibrary.org/obo/GO_0019647 GO:0019648 biolink:BiologicalProcess formaldehyde assimilation via xylulose monophosphate cycle The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds. MetaCyc:P185-PWY go-plus.json formaldehyde assimilation via xylulose-5-phosphate cycle|formaldehyde fixation cycle http://purl.obolibrary.org/obo/GO_0019648 CHEBI:139504 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139504 chebi_ph7_3 GO:0019645 biolink:BiologicalProcess anaerobic electron transport chain A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0019645 GO:0019646 biolink:BiologicalProcess aerobic electron transport chain A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient. go-plus.json NADH-O2 electron transport|ubiquinone-8-O2 electron transport|succinate-O2 electron transport http://purl.obolibrary.org/obo/GO_0019646 CHEBI:139505 biolink:ChemicalSubstance baeocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139505 GO:0019643 biolink:BiologicalProcess reductive tricarboxylic acid cycle A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate. MetaCyc:P23-PWY|MetaCyc:REDCITCYC go-plus.json reductive Kreb's cycle|reductive carboxylate cycle|reductive citric acid pathway|reductive carboxylic acid cycle|reductive TCA cycle http://purl.obolibrary.org/obo/GO_0019643 CHEBI:57459 biolink:ChemicalSubstance (6S)-6-hydroxyhyoscyaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57459 chebi_ph7_3 GO:0019644 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019644 CHEBI:139500 biolink:ChemicalSubstance N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139500 chebi_ph7_3 CHEBI:57457 biolink:ChemicalSubstance (6S)-5-formyltetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57457 chebi_ph7_3 GO:0019641 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019641 GO:0019642 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019642 CHEBI:57458 biolink:ChemicalSubstance (S)-NADHX(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57458 CHEBI:57455 biolink:ChemicalSubstance (6R)-5,10-methenyltetrahydrofolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57455 chebi_ph7_3 GO:0019640 biolink:BiologicalProcess glucuronate catabolic process to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate. go-plus.json glucuronate degradation to xylulose 5-phosphate|glucuronate breakdown to xylulose 5-phosphate http://purl.obolibrary.org/obo/GO_0019640 CHEBI:57456 biolink:ChemicalSubstance 5-formimidoyltetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57456 chebi_ph7_3 CHEBI:57453 biolink:ChemicalSubstance (6S)-5,6,7,8-tetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57453 chebi_ph7_3 CHEBI:57454 biolink:ChemicalSubstance 10-formyltetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57454 chebi_ph7_3 GO:0030093 biolink:CellularComponent chloroplast photosystem I Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0030093 GO:0030094 biolink:CellularComponent plasma membrane-derived photosystem I A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species. go-plus.json plasma membrane photosystem I http://purl.obolibrary.org/obo/GO_0030094 GO:0030091 biolink:BiologicalProcess protein repair The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues. go-plus.json http://purl.obolibrary.org/obo/GO_0030091 GO:0030092 biolink:BiologicalProcess obsolete regulation of flagellum assembly OBSOLETE. Any process that modulates the frequency, rate or extent of the formation of a flagellum. go-plus.json regulation of flagellum assembly|regulation of flagella assembly|regulation of flagella biogenesis|regulation of flagellum biogenesis http://purl.obolibrary.org/obo/GO_0030092 GO:0030090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030090 GO:0030099 biolink:BiologicalProcess myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. go-plus.json http://purl.obolibrary.org/obo/GO_0030099 GO:0030097 biolink:BiologicalProcess hemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. Wikipedia:Haematopoiesis go-plus.json blood cell biosynthesis|blood cell formation|hematopoiesis|haemopoiesis http://purl.obolibrary.org/obo/GO_0030097 GO:0030098 biolink:BiologicalProcess lymphocyte differentiation The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. go-plus.json lymphocytic blood cell differentiation|lymphocyte cell differentiation|lymphocyte development http://purl.obolibrary.org/obo/GO_0030098 GO:0030095 biolink:CellularComponent chloroplast photosystem II An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone. go-plus.json http://purl.obolibrary.org/obo/GO_0030095 GO:0030096 biolink:CellularComponent plasma membrane-derived thylakoid photosystem II A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone. go-plus.json plasma membrane photosystem II http://purl.obolibrary.org/obo/GO_0030096 GO:0030082 biolink:CellularComponent B800-850 antenna complex Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex. go-plus.json light harvesting complex II|LH2 complex http://purl.obolibrary.org/obo/GO_0030082 GO:0030083 biolink:CellularComponent PSI associated light-harvesting complex I, LHCIa subcomplex A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm. go-plus.json http://purl.obolibrary.org/obo/GO_0030083 GO:0030080 biolink:CellularComponent B875 antenna complex Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm. go-plus.json LH1 complex|light harvesting complex I http://purl.obolibrary.org/obo/GO_0030080 GO:0030081 biolink:CellularComponent B800-820 antenna complex Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex. go-plus.json LH3 complex|light harvesting complex III http://purl.obolibrary.org/obo/GO_0030081 GO:0030088 biolink:CellularComponent obsolete PSII associated light-harvesting complex II, core complex, LHCIId subcomplex OBSOLETE. (Was not defined before being made obsolete). go-plus.json PSII associated light-harvesting complex II, core complex, LHCIId subcomplex http://purl.obolibrary.org/obo/GO_0030088 GO:0030089 biolink:CellularComponent phycobilisome Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II. Wikipedia:Phycobilisome go-plus.json http://purl.obolibrary.org/obo/GO_0030089 GO:0030086 biolink:CellularComponent obsolete PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex OBSOLETE. (Was not defined before being made obsolete). go-plus.json PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex http://purl.obolibrary.org/obo/GO_0030086 GO:0030087 biolink:CellularComponent obsolete PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex OBSOLETE. (Was not defined before being made obsolete). go-plus.json PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex http://purl.obolibrary.org/obo/GO_0030087 GO:0030084 biolink:CellularComponent PSI associated light-harvesting complex I, LHCIb subcomplex A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm. go-plus.json http://purl.obolibrary.org/obo/GO_0030084 GO:0030085 biolink:CellularComponent PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides. go-plus.json http://purl.obolibrary.org/obo/GO_0030085 GO:0044600 biolink:MolecularActivity protein guanylyltransferase activity Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0044600 GO:0044607 biolink:BiologicalProcess obsolete disruption by symbiont of host endothelial cells OBSOLETE. Any process in which an organism has a negative effect on the functioning of the host's endothelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044607 GO:0030071 biolink:BiologicalProcess regulation of mitotic metaphase/anaphase transition Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. go-plus.json http://purl.obolibrary.org/obo/GO_0030071 GO:0030072 biolink:BiologicalProcess peptide hormone secretion The regulated release of a peptide hormone from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030072 GO:0044608 biolink:BiologicalProcess peptidyl-L-threonine methyl ester biosynthetic process from peptidyl-threonine The modification of a C-terminal peptidyl-threonine to form peptidyl-L-threonine methyl ester. RESID:AA0507 go-plus.json peptidyl-threonine esterification http://purl.obolibrary.org/obo/GO_0044608 GO:0044605 biolink:MolecularActivity phosphocholine transferase activity Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0044605 GO:0044606 biolink:MolecularActivity phosphocholine hydrolase activity Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0044606 GO:0030070 biolink:BiologicalProcess insulin processing The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges. go-plus.json http://purl.obolibrary.org/obo/GO_0030070 GO:0044603 biolink:MolecularActivity protein adenylylhydrolase activity Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins. go-plus.json protein deAMPylase activity|protein deAMPylation activity http://purl.obolibrary.org/obo/GO_0044603 GO:0044604 biolink:MolecularActivity ABC-type phytochelatin transporter activity Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. go-plus.json ABC-type phytochelatin transmembrane transporter activity|phytochelatin transmembrane transporter activity|phytochelatin transporter activity|cadystin transmembrane transporter activity|ATPase-coupled phytochelatin transmembrane transporter activity|cadystin transmembrane transporter ATPase activity|ATP-dependent phytochelatin transmembrane transporter activity|cadystin transporter activity|phytochelatin transmembrane transporter ATPase activity http://purl.obolibrary.org/obo/GO_0044604 GO:0044601 biolink:BiologicalProcess protein denucleotidylation The removal of a nucleotide from a protein amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0044601 GO:0044602 biolink:BiologicalProcess protein deadenylylation The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid. go-plus.json protein deAMPylation http://purl.obolibrary.org/obo/GO_0044602 GO:0030079 biolink:CellularComponent light-harvesting complex, peripheral complex Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center. go-plus.json http://purl.obolibrary.org/obo/GO_0030079 GO:0030077 biolink:CellularComponent plasma membrane light-harvesting complex A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species. go-plus.json http://purl.obolibrary.org/obo/GO_0030077 GO:0030078 biolink:CellularComponent light-harvesting complex, core complex Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0030078 NCBITaxon:1437201 biolink:OrganismalEntity Pentapetalae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1437201 GO:0030075 biolink:CellularComponent bacterial thylakoid A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria. go-plus.json plasma membrane-derived thylakoid http://purl.obolibrary.org/obo/GO_0030075 GO:0030076 biolink:CellularComponent light-harvesting complex A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Wikipedia:Light-harvesting_complex go-plus.json antenna complex http://purl.obolibrary.org/obo/GO_0030076 goslim_pir GO:0044609 biolink:CellularComponent DBIRD complex A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD. go-plus.json http://purl.obolibrary.org/obo/GO_0044609 GO:0030073 biolink:BiologicalProcess insulin secretion The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. go-plus.json http://purl.obolibrary.org/obo/GO_0030073 GO:0030074 biolink:CellularComponent obsolete thylakoid (sensu Proteobacteria) OBSOLETE. A thylakoid; as in, but not restricted to, the purple bacteria and relatives (Proteobacteria, ncbi_taxonomy_id:1224). go-plus.json thylakoid (sensu Proteobacteria) http://purl.obolibrary.org/obo/GO_0030074 UBERON:0004190 biolink:AnatomicalEntity renal glomerulus vasculature The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus go-plus.json glomerulus vasculature|renal glomerulus vasculature|vascular network of renal glomerulus|renal glomerulus vascular network|vasculature of renal glomerulus http://purl.obolibrary.org/obo/UBERON_0004190 GO:0044610 biolink:MolecularActivity FMN transmembrane transporter activity Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other. go-plus.json flavine mononucleotide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0044610 GO:0044611 biolink:CellularComponent nuclear pore inner ring A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex. go-plus.json Nup170 complex http://purl.obolibrary.org/obo/GO_0044611 GO:0030060 biolink:MolecularActivity L-malate dehydrogenase activity Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+. Reactome:R-HSA-70979|EC:1.1.1.37|RHEA:21432|Reactome:R-HSA-71783|MetaCyc:MALATE-DEH-RXN|Reactome:R-HSA-198508 go-plus.json L-malate-NAD+ oxidoreductase activity|NAD-dependent malic dehydrogenase activity|(S)-malate:NAD+ oxidoreductase activity|NAD-malate dehydrogenase activity|NAD-malic dehydrogenase activity|NAD-dependent malate dehydrogenase activity|malate (NAD) dehydrogenase activity|NAD-linked malate dehydrogenase activity|malic acid dehydrogenase activity|MDH|NAD-specific malate dehydrogenase activity|NAD-L-malate dehydrogenase activity|malic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0030060 GO:0044618 biolink:BiologicalProcess modulation of relaxation of uterine smooth muscle in other organism The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism. go-plus.json regulation of relaxation of uterine smooth muscle in other organism http://purl.obolibrary.org/obo/GO_0044618 UBERON:0004198 biolink:AnatomicalEntity comma-shaped body The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron go-plus.json CSB http://purl.obolibrary.org/obo/UBERON_0004198 GO:0044619 biolink:BiologicalProcess positive regulation of relaxation of uterine smooth muscle in other organism The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044619 GO:0030061 biolink:CellularComponent mitochondrial crista Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria. NIF_Subcellular:sao333328131 go-plus.json cristae|mitochondrial cristae http://purl.obolibrary.org/obo/GO_0030061 UBERON:0004199 biolink:AnatomicalEntity S-shaped body The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron go-plus.json stage II nephron|SSB http://purl.obolibrary.org/obo/UBERON_0004199 GO:0044616 biolink:BiologicalProcess modulation of relaxation of muscle in other organism The process in which an organism effects a change in the relaxation of muscle in a second organism. go-plus.json regulation of relaxation of muscle in other organism http://purl.obolibrary.org/obo/GO_0044616 UBERON:0004196 biolink:AnatomicalEntity proximal convoluted tubule segment 1 The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]. go-plus.json segment 1 of proximal tubule|S1 portion of tubule|proximal tubule segment 1|S1 portion of renal tubule|S1 http://purl.obolibrary.org/obo/UBERON_0004196 GO:0044617 biolink:BiologicalProcess modulation of relaxation of smooth muscle in other organism The process in which an organism effects a change in the relaxation of smooth muscle in a second organism. go-plus.json regulation of relaxation of smooth muscle in other organism http://purl.obolibrary.org/obo/GO_0044617 UBERON:0004197 biolink:AnatomicalEntity proximal convoluted tubule segment 2 The S2 portion of the tubule is involved in reabsorption of water and sodium chloride[GO]. go-plus.json segment 2 of proximal tubule|S2 portion of tubule|proximal tubule segment 2|S2 portion of renal tubule|S2 http://purl.obolibrary.org/obo/UBERON_0004197 GO:0044614 biolink:CellularComponent nuclear pore cytoplasmic filaments Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component. go-plus.json cytoplasmic fibers of the nuclear pore complex|cytoplasmic fibers of the NPC http://purl.obolibrary.org/obo/GO_0044614 UBERON:0004194 biolink:AnatomicalEntity long nephron Long nephrons are associated with juxtamedullary glomeruli and extend to the inner medulla go-plus.json juxtamedullary nephron http://purl.obolibrary.org/obo/UBERON_0004194 GO:0044615 biolink:CellularComponent nuclear pore nuclear basket A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component. go-plus.json http://purl.obolibrary.org/obo/GO_0044615 UBERON:0004195 biolink:AnatomicalEntity short nephron Short nephrons are associated with mid-cortical glomeruli, and have no short ascending limb, so the limb is situated in the outer medulla go-plus.json http://purl.obolibrary.org/obo/UBERON_0004195 GO:0044612 biolink:CellularComponent nuclear pore linkers A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p). go-plus.json Nup82 complex|Nic96 complex http://purl.obolibrary.org/obo/GO_0044612 UBERON:0004193 biolink:AnatomicalEntity loop of Henle ascending limb thin segment A sub-portion of the loop of Henle in the nephron of the kidney that is permeable to ions but not to water go-plus.json pars ascendens (tubulus attenuatus)|ascending limb thin segment of loop of Henle|thin ascending limb|thin ascending limb of loop of Henle|ascending thin limb http://purl.obolibrary.org/obo/UBERON_0004193 GO:0044613 biolink:CellularComponent nuclear pore central transport channel The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153. go-plus.json nuclear pore central plug|nuclear pore central channel|nuclear pore transport channel|karyopherin docking complex http://purl.obolibrary.org/obo/GO_0044613 GO:0030068 biolink:BiologicalProcess obsolete lytic viral life cycle OBSOLETE. (Was not defined before being made obsolete). go-plus.json lytic viral life cycle http://purl.obolibrary.org/obo/GO_0030068 GO:0030069 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030069 GO:0030066 biolink:MolecularActivity obsolete cytochrome b6 OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytochrome b-563|cytochrome b6 http://purl.obolibrary.org/obo/GO_0030066 GO:0030067 biolink:MolecularActivity obsolete respiratory chain cytochrome b6 OBSOLETE. (Was not defined before being made obsolete). go-plus.json respiratory chain cytochrome b6 http://purl.obolibrary.org/obo/GO_0030067 GO:0030064 biolink:CellularComponent obsolete cell wall inner membrane OBSOLETE. The peptidoglycan layer of the cell wall of Gram-negative bacteria. go-plus.json cell wall inner membrane http://purl.obolibrary.org/obo/GO_0030064 GO:0030065 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030065 GO:0030062 biolink:CellularComponent mitochondrial tricarboxylic acid cycle enzyme complex Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle. go-plus.json TCA cycle enzyme complex http://purl.obolibrary.org/obo/GO_0030062 GO:0030063 biolink:CellularComponent obsolete murein sacculus OBSOLETE. A structure formed of the cross-linked polymer peptidoglycan (also called murein) that forms a covalently closed net around a bacterial cell, and imparts structural stability to the bacterial cell wall. go-plus.json peptidoglycan layer|murein sacculus http://purl.obolibrary.org/obo/GO_0030063 PR:000018345 biolink:Protein interleukin-1 beta proteolytic cleavage product An interleukin-1 beta that has been processed by proteolytic cleavage. go-plus.json IL1B/ClvPrd http://purl.obolibrary.org/obo/PR_000018345 GO:0030059 biolink:MolecularActivity aralkylamine dehydrogenase (azurin) activity Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin]. EC:1.4.9.2|RHEA:47796|MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN go-plus.json aromatic amine dehydrogenase (azurin) activity|aralkylamine:(azurin) oxidoreductase (deaminating) activity http://purl.obolibrary.org/obo/GO_0030059 GO:0044621 biolink:BiologicalProcess modulation of cell migration in other organism The process in which an organism effects a change in the process of cell migration in a second organism. go-plus.json regulation of cell migration in other organism http://purl.obolibrary.org/obo/GO_0044621 CHEBI:140597 biolink:ChemicalSubstance disubstituted aliphatic (S)-cyanohydrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140597 chebi_ph7_3 GO:0044622 biolink:BiologicalProcess negative regulation of cell migration in other organism Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044622 GO:0005099 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005099 CHEBI:140595 biolink:ChemicalSubstance 1-[(1Z)-octadecenyl]-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140595 GO:0044620 biolink:MolecularActivity ACP phosphopantetheine attachment site binding Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP). go-plus.json http://purl.obolibrary.org/obo/GO_0044620 CHEBI:140596 biolink:ChemicalSubstance monosubstituted aliphatic (S)-cyanohydrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140596 chebi_ph7_3 GO:0005097 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005097 CHEBI:140593 biolink:ChemicalSubstance N-acyl-1-[(1Z)-alkenyl]-2-acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140593 GO:0005098 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005098 CHEBI:140594 biolink:ChemicalSubstance ethanediol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_140594 chebi_ph7_3 GO:0005095 biolink:MolecularActivity GTPase inhibitor activity Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate. go-plus.json GIP http://purl.obolibrary.org/obo/GO_0005095 GO:0005096 biolink:MolecularActivity GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. Reactome:R-HSA-8985594|Reactome:R-HSA-416546|Reactome:R-HSA-5638007|Reactome:R-HSA-399935|Reactome:R-HSA-4093339|Reactome:R-HSA-194922|Reactome:R-HSA-428533|Reactome:R-HSA-9624893|Reactome:R-HSA-428522|Reactome:R-HSA-392513|Reactome:R-HSA-416559 go-plus.json Rac GAP activity|ARF GAP activity|ARF GTPase activator activity|Rac GTPase activator activity|Rab GTPase activator activity|Rho GAP activity|Ral GAP activity|RanGAP|Ran GAP activity|Rap GAP activity|GAP activity|Sar GAP activity|Ras GAP activity|Ras GTPase activator activity|Sar GTPase activator activity|Rap GTPase activator activity|Ran GTPase activator activity|Ral GTPase activator activity|Rho GTPase activator activity|Rab GAP activity http://purl.obolibrary.org/obo/GO_0005096 GO:0044629 biolink:BiologicalProcess negative regulation of complement activation, classical pathway in other organism Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044629 GO:0030050 biolink:BiologicalProcess vesicle transport along actin filament Movement of a vesicle along an actin filament, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030050 GO:0044627 biolink:BiologicalProcess modulation of complement activation, classical pathway in other organism A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism. go-plus.json regulation of complement activation, classical pathway in other organism http://purl.obolibrary.org/obo/GO_0044627 GO:0044628 biolink:BiologicalProcess positive regulation of complement activation, classical pathway in other organism Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044628 GO:0044625 biolink:BiologicalProcess envenomation resulting in negative regulation of cell migration in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of cell migration in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044625 GO:0044626 biolink:BiologicalProcess envenomation resulting in positive regulation of cell migration in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of cell migration in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044626 GO:0044623 biolink:BiologicalProcess positive regulation of cell migration in other organism Any process that activates or increases the frequency, rate or extent of cell migration in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044623 CHEBI:140599 biolink:ChemicalSubstance alpha-D-xylose-(1->3)-alpha-D-xylose-(1->3)-beta-D-glucose-L-seryl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140599 chebi_ph7_3 GO:0044624 biolink:BiologicalProcess envenomation resulting in modulation of cell migration in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of cell migration in the bitten organism. go-plus.json envenomation resulting in regulation of cell migration in other organism http://purl.obolibrary.org/obo/GO_0044624 CHEBI:139597 biolink:ChemicalSubstance O(3)-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139597 chebi_ph7_3 GO:0030057 biolink:CellularComponent desmosome A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. Wikipedia:Desmosome go-plus.json spot desmosome|macula adherens http://purl.obolibrary.org/obo/GO_0030057 GO:0030058 biolink:MolecularActivity amine dehydrogenase activity Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+. UM-BBD_enzymeID:e0058|RHEA:51128 go-plus.json amine: (acceptor) oxidoreductase (deaminating)|MADH activity|primary-amine dehydrogenase activity|primary-amine:acceptor oxidoreductase (deaminating)|methylamine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0030058 CHEBI:139598 biolink:ChemicalSubstance O(3)-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139598 chebi_ph7_3 GO:0030055 biolink:CellularComponent cell-substrate junction A cell junction that forms a connection between a cell and the extracellular matrix. go-plus.json cell-matrix junction http://purl.obolibrary.org/obo/GO_0030055 GO:0030056 biolink:CellularComponent hemidesmosome A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces. Wikipedia:Hemidesmosome go-plus.json fibrous organelle|hemi-adherens junction|trans-epithelial attachment|epidermal attachment structure http://purl.obolibrary.org/obo/GO_0030056 GO:0030053 biolink:MolecularActivity obsolete immunophilin OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin. go-plus.json immunophilin http://purl.obolibrary.org/obo/GO_0030053 CHEBI:139593 biolink:ChemicalSubstance 4-O-methylxanthohumol go-plus.json http://purl.obolibrary.org/obo/CHEBI_139593 GO:0030054 biolink:CellularComponent cell junction A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. Wikipedia:Cell_junction go-plus.json http://purl.obolibrary.org/obo/GO_0030054 goslim_agr|goslim_drosophila|goslim_flybase_ribbon GO:0030051 biolink:MolecularActivity obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0)). go-plus.json FKBP|FK506-sensitive peptidyl-prolyl cis-trans isomerase|FK506 binding protein http://purl.obolibrary.org/obo/GO_0030051 GO:0030052 biolink:MolecularActivity obsolete parvulin OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin. go-plus.json parvulin http://purl.obolibrary.org/obo/GO_0030052 CHEBI:139596 biolink:ChemicalSubstance N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139596 chebi_ph7_3 GO:0030048 biolink:BiologicalProcess actin filament-based movement Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030048 GO:0030049 biolink:BiologicalProcess muscle filament sliding The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated. go-plus.json http://purl.obolibrary.org/obo/GO_0030049 GO:0044632 biolink:BiologicalProcess negative regulation of complement activation, lectin pathway in other organism Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044632 GO:0044633 biolink:BiologicalProcess modulation of complement activation, alternative pathway in other organism A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism. go-plus.json regulation of complement activation, alternative pathway in other organism http://purl.obolibrary.org/obo/GO_0044633 GO:0044630 biolink:BiologicalProcess modulation of complement activation, lectin pathway in other organism A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism. go-plus.json regulation of complement activation, lectin pathway in other organism http://purl.obolibrary.org/obo/GO_0044630 GO:0044631 biolink:BiologicalProcess positive regulation of complement activation, lectin pathway in other organism Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044631 GO:0044638 biolink:BiologicalProcess envenomation resulting in positive regulation of complement activation, classical pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044638 GO:0044639 biolink:BiologicalProcess envenomation resulting in modulation of complement activation, lectin pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism. go-plus.json envenomation resulting in regulation of complement activation, lectin pathway in other organism http://purl.obolibrary.org/obo/GO_0044639 GO:0044636 biolink:BiologicalProcess envenomation resulting in modulation of complement activation, classical pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044636 GO:0044637 biolink:BiologicalProcess envenomation resulting in negative regulation of complement activation, classical pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044637 GO:0044634 biolink:BiologicalProcess negative regulation of complement activation, alternative pathway in other organism Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044634 GO:0044635 biolink:BiologicalProcess positive regulation of complement activation, alternative pathway in other organism Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044635 GO:0030046 biolink:BiologicalProcess parallel actin filament bundle assembly Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0030046 GO:0030047 biolink:BiologicalProcess actin modification Covalent modification of an actin molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0030047 GO:0030044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030044 GO:0030045 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030045 GO:0030042 biolink:BiologicalProcess actin filament depolymerization Disassembly of actin filaments by the removal of actin monomers from a filament. go-plus.json actin depolymerization|actin depolymerizing activity http://purl.obolibrary.org/obo/GO_0030042 GO:0030043 biolink:BiologicalProcess actin filament fragmentation The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030043 PR:000018344 biolink:Protein interleukin-1 alpha proteolytic cleavage product An interleukin-1 alpha that has been processed by proteolytic cleavage. go-plus.json IL1A/ClvPrd http://purl.obolibrary.org/obo/PR_000018344 GO:0030040 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030040 GO:0030041 biolink:BiologicalProcess actin filament polymerization Assembly of actin filaments by the addition of actin monomers to a filament. go-plus.json actin polymerization|actin polymerizing activity http://purl.obolibrary.org/obo/GO_0030041 CHEBI:139580 biolink:ChemicalSubstance O(3)-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139580 chebi_ph7_3 CHEBI:139581 biolink:ChemicalSubstance O(3)-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139581 chebi_ph7_3 GO:0030039 biolink:MolecularActivity obsolete DNA unwinding factor OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA unwinding factor http://purl.obolibrary.org/obo/GO_0030039 GO:0030037 biolink:BiologicalProcess actin filament reorganization involved in cell cycle The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs. go-plus.json actin filament reorganization during cell cycle|actin filament reorganisation involved in cell cycle http://purl.obolibrary.org/obo/GO_0030037 GO:0030038 biolink:BiologicalProcess contractile actin filament bundle assembly Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle. go-plus.json http://purl.obolibrary.org/obo/GO_0030038 GO:0005079 biolink:MolecularActivity obsolete protein kinase A anchoring activity OBSOLETE. Binds to protein kinase A and anchors it to a particular subcellular location. go-plus.json A-kinase anchor protein activity|protein kinase A anchoring activity|AKAP activity http://purl.obolibrary.org/obo/GO_0005079 GO:0044643 biolink:BiologicalProcess envenomation resulting in positive regulation of complement activation, alternative pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044643 CHEBI:140575 biolink:ChemicalSubstance alpha-D-xylose-(1->3)-beta-D-glucose-L-seryl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140575 chebi_ph7_3 GO:0044644 biolink:BiologicalProcess envenomation resulting in negative regulation of complement activation, alternative pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044644 CHEBI:140576 biolink:ChemicalSubstance beta-D-glucose-L-seryl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140576 chebi_ph7_3 GO:0005077 biolink:MolecularActivity obsolete MAP-kinase anchoring activity OBSOLETE. Binds to MAP kinase and anchors it to a particular subcellular location. go-plus.json MAP-kinase anchor protein activity|MAP-kinase anchoring activity http://purl.obolibrary.org/obo/GO_0005077 GO:0044641 biolink:BiologicalProcess envenomation resulting in positive regulation of complement activation, lectin pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044641 CHEBI:140573 biolink:ChemicalSubstance alpha-D-glucosyl-L-tyrosyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140573 chebi_ph7_3 GO:0005078 biolink:MolecularActivity MAP-kinase scaffold activity The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently. go-plus.json MAP-kinase scaffold protein activity http://purl.obolibrary.org/obo/GO_0005078 GO:0044642 biolink:BiologicalProcess envenomation resulting in modulation of complement activation, alternative pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism. go-plus.json envenomation resulting in regulation of complement activation, alternative pathway in other organism http://purl.obolibrary.org/obo/GO_0044642 CHEBI:140574 biolink:ChemicalSubstance (1,4-alpha-D-glucosyl)(n)-L-tyrosyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140574 chebi_ph7_3 GO:0005075 biolink:MolecularActivity obsolete pathway-specific SMAD protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json pathway-specific SMAD protein http://purl.obolibrary.org/obo/GO_0005075 GO:0005076 biolink:MolecularActivity obsolete receptor signaling protein serine/threonine kinase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json receptor signaling protein serine/threonine kinase signaling protein activity|receptor signalling protein serine/threonine kinase signalling protein activity http://purl.obolibrary.org/obo/GO_0005076 GO:0044640 biolink:BiologicalProcess envenomation resulting in negative regulation of complement activation, lectin pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044640 CHEBI:140572 biolink:ChemicalSubstance heparan sulfate alpha-D-N-sulfoglucosamine polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140572 chebi_ph7_3 CHEBI:82464 biolink:ChemicalSubstance cis-9,10-epoxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82464 GO:0005073 biolink:MolecularActivity obsolete common-partner SMAD protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json common-partner SMAD protein http://purl.obolibrary.org/obo/GO_0005073 GO:0005074 biolink:MolecularActivity obsolete inhibitory SMAD protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json inhibitory SMAD protein http://purl.obolibrary.org/obo/GO_0005074 GO:0005082 biolink:MolecularActivity obsolete receptor signaling protein tyrosine phosphatase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json receptor signaling protein tyrosine phosphatase signaling protein activity|receptor signalling protein tyrosine phosphatase signalling protein activity http://purl.obolibrary.org/obo/GO_0005082 GO:0005083 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005083 GO:0005080 biolink:MolecularActivity protein kinase C binding Binding to protein kinase C. go-plus.json PKC binding|protein kinase C alpha binding|PKC alpha binding|protein kinase C delta binding|protein kinase C eta binding|PKC delta binding|PKC eta binding http://purl.obolibrary.org/obo/GO_0005080 GO:0044649 biolink:BiologicalProcess envenomation resulting in cytolysis in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with cytolysis in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044649 GO:0005081 biolink:MolecularActivity obsolete receptor signaling protein serine/threonine phosphatase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json receptor signaling protein serine/threonine phosphatase signaling protein activity|receptor signalling protein serine/threonine phosphatase signalling protein activity http://purl.obolibrary.org/obo/GO_0005081 GO:0044647 biolink:CellularComponent host-symbiont bicellular tight junction An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane. go-plus.json host-pathogen tight junction|host-parasite tight junction http://purl.obolibrary.org/obo/GO_0044647 GO:0044648 biolink:BiologicalProcess histone H3-K4 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0044648 GO:0044645 biolink:BiologicalProcess modulation of complement activation in other organism A process that modulates the frequency, rate or extent of complement activation in a different organism. go-plus.json regulation of complement activation in other organism http://purl.obolibrary.org/obo/GO_0044645 CHEBI:140577 biolink:ChemicalSubstance beta-D-glucosyl-L-threonyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140577 chebi_ph7_3 GO:0044646 biolink:BiologicalProcess envenomation resulting in modulation of complement activation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism. go-plus.json envenomation resulting in regulation of complement activation in other organism http://purl.obolibrary.org/obo/GO_0044646 PR:000008998 biolink:Protein interleukin-21 receptor A protein that is a translation product of the human IL21R gene or a 1:1 ortholog thereof. go-plus.json LR-beta|NR8|IL-21 receptor|lymphocyte receptor beta|novel interleukin receptor|IL21R|CD360|novel cytokine receptor 8|IL-21R|NILR http://purl.obolibrary.org/obo/PR_000008998 CHEBI:140578 biolink:ChemicalSubstance alpha-D-xylose-(1->3)-beta-D-glucose-L-threonyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140578 chebi_ph7_3 GO:0030035 biolink:BiologicalProcess microspike assembly Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell. go-plus.json microspike biogenesis|microspike formation|microspike biosynthesis http://purl.obolibrary.org/obo/GO_0030035 CHEBI:139575 biolink:ChemicalSubstance monounsaturated fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139575 GO:0030036 biolink:BiologicalProcess actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. go-plus.json actin cytoskeleton organization and biogenesis|actin cytoskeleton organisation|actin modulating activity http://purl.obolibrary.org/obo/GO_0030036 goslim_drosophila|goslim_pombe CHEBI:139576 biolink:ChemicalSubstance octadecatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139576 GO:0030033 biolink:BiologicalProcess microvillus assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. go-plus.json microvillus biogenesis http://purl.obolibrary.org/obo/GO_0030033 GO:0030034 biolink:BiologicalProcess microvillar actin bundle assembly Assembly of the parallel bundle of actin filaments at the core of a microvillus. go-plus.json http://purl.obolibrary.org/obo/GO_0030034 CHEBI:139578 biolink:ChemicalSubstance octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139578 GO:0030031 biolink:BiologicalProcess cell projection assembly Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. go-plus.json cell projection biogenesis|formation of a cell surface projection http://purl.obolibrary.org/obo/GO_0030031 PO:0028002 biolink:OntologyClass sporophyte development stage A whole plant development stage (PO:0007033) that has as primary participant a whole plant (PO:0000003) during the interval between fertilization (or apogamy) and death. go-plus.json sporophytic phase (exact)|fase esporofítica (Spanish, exact)|sporophytic development stage (exact)|sporphyte phase (exact)|胞子体発生過程 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0028002 CHEBI:139571 biolink:ChemicalSubstance 8-carboxy-8-demethylriboflavin 5'-phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139571 chebi_ph7_3 GO:0030032 biolink:BiologicalProcess lamellipodium assembly Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. go-plus.json lamellipodium biosynthesis|lamellipodium formation|lamellipodium biogenesis http://purl.obolibrary.org/obo/GO_0030032 CHEBI:139572 biolink:ChemicalSubstance hexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139572 chebi_ph7_3 GO:0030030 biolink:BiologicalProcess cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. go-plus.json cell surface structure organization and biogenesis|cell projection organisation|cell projection organization and biogenesis http://purl.obolibrary.org/obo/GO_0030030 CHEBI:139574 biolink:ChemicalSubstance octadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139574 CHEBI:139590 biolink:ChemicalSubstance primary alpha-hydroxy ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_139590 chebi_ph7_3 CHEBI:139592 biolink:ChemicalSubstance tertiary alpha-hydroxy ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_139592 chebi_ph7_3 GO:0030028 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030028 GO:0030029 biolink:BiologicalProcess actin filament-based process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. go-plus.json microfilament-based process http://purl.obolibrary.org/obo/GO_0030029 GO:0030026 biolink:BiologicalProcess cellular manganese ion homeostasis Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell. go-plus.json manganese homeostasis http://purl.obolibrary.org/obo/GO_0030026 OBO:uberon/core#transitively_distally_connected_to biolink:OntologyClass transitively distally connected to . transitively_distally_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to GO:0030027 biolink:CellularComponent lamellipodium A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments. Wikipedia:Lamellipodia go-plus.json http://purl.obolibrary.org/obo/GO_0030027 CHEBI:140564 biolink:ChemicalSubstance delta-cadinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_140564 chebi_ph7_3 GO:0044654 biolink:MolecularActivity starch alpha-glucosidase activity Catalysis of the reaction: starch + H2O = alpha-D-glucose. EC:3.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0044654 GO:0044655 biolink:BiologicalProcess phagosome reneutralization Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation. go-plus.json phagosomal reneutralization|phagosome pH elevation http://purl.obolibrary.org/obo/GO_0044655 GO:0044652 biolink:BiologicalProcess adhesion of symbiont to host endothelial cell The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly. go-plus.json http://purl.obolibrary.org/obo/GO_0044652 GO:0005088 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005088 GO:0044653 biolink:MolecularActivity dextrin alpha-glucosidase activity Catalysis of the reaction: dextrin + H2O = alpha-D-glucose. EC:3.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0044653 GO:0005089 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005089 GO:0044650 biolink:BiologicalProcess adhesion of symbiont to host cell The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly. go-plus.json http://purl.obolibrary.org/obo/GO_0044650 GO:0005086 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005086 CHEBI:140561 biolink:ChemicalSubstance (1->4)-3,6-bis(phospho)-alpha-D-glucan polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140561 chebi_ph7_3 GO:0044651 biolink:BiologicalProcess adhesion of symbiont to host epithelial cell The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly. go-plus.json http://purl.obolibrary.org/obo/GO_0044651 GO:0005087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005087 GO:0005084 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005084 NCBITaxon:29202 biolink:OrganismalEntity Thalassiosiraceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_29202 GO:0005085 biolink:MolecularActivity guanyl-nucleotide exchange factor activity Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. Reactome:R-HSA-5218829|Reactome:R-HSA-442732|Reactome:R-HSA-350769|Reactome:R-HSA-9695853|Reactome:R-HSA-5655347|Reactome:R-HSA-171026|Reactome:R-HSA-1306972|Reactome:R-HSA-420883|Reactome:R-HSA-9664991|Reactome:R-HSA-2730840|Reactome:R-HSA-399995|Reactome:R-HSA-5637808|Reactome:R-HSA-5655326|Reactome:R-HSA-416530|Reactome:R-HSA-6811414|Reactome:R-HSA-8877311|Reactome:R-HSA-3928633|Reactome:R-HSA-210977|Reactome:R-HSA-442314|Reactome:R-HSA-418856|Reactome:R-HSA-180687|Reactome:R-HSA-9607304|Reactome:R-HSA-9639286|Reactome:R-HSA-8877998|Reactome:R-HSA-9660824|Reactome:R-HSA-9026891|Reactome:R-HSA-5655277|Reactome:R-HSA-9033292|Reactome:R-HSA-9665707|Reactome:R-HSA-3928632|Reactome:R-HSA-379048|Reactome:R-HSA-169904|Reactome:R-HSA-8877308|Reactome:R-HSA-109817|Reactome:R-HSA-8876190|Reactome:R-HSA-5637806|Reactome:R-HSA-187746|Reactome:R-HSA-8876191|Reactome:R-HSA-9032067|Reactome:R-HSA-1250463|Reactome:R-HSA-2029445|Reactome:R-HSA-8876616|Reactome:R-HSA-156913|Reactome:R-HSA-2029451|Reactome:R-HSA-186834|Reactome:R-HSA-5655241|Reactome:R-HSA-5617816|Reactome:R-HSA-8850041|Reactome:R-HSA-428917|Reactome:R-HSA-9032798|Reactome:R-HSA-3928612|Reactome:R-HSA-109807|Reactome:R-HSA-9670436|Reactome:R-HSA-9029158|Reactome:R-HSA-8876188|Reactome:R-HSA-3928628|Reactome:R-HSA-6811429|Reactome:R-HSA-8982637|Reactome:R-HSA-9666428|Reactome:R-HSA-8851827|Reactome:R-HSA-5654426|Reactome:R-HSA-8876454|Reactome:R-HSA-5623521|Reactome:R-HSA-9672163|Reactome:R-HSA-5218850|Reactome:R-HSA-8877612|Reactome:R-HSA-2029467|Reactome:R-HSA-5654647|Reactome:R-HSA-399938|Reactome:R-HSA-8877813|Reactome:R-HSA-9665700|Reactome:R-HSA-418850|Reactome:R-HSA-2424476|Reactome:R-HSA-442291|Reactome:R-HSA-9666430|Reactome:R-HSA-751029|Reactome:R-HSA-3928642|Reactome:R-HSA-5672965|Reactome:R-HSA-9703441|Reactome:R-HSA-2424477|Reactome:R-HSA-8851877|Reactome:R-HSA-5218839|Reactome:R-HSA-177938|Reactome:R-HSA-9665408|Reactome:R-HSA-825631|Reactome:R-HSA-5654402|Reactome:R-HSA-5654600|Reactome:R-HSA-392870|Reactome:R-HSA-8876193|Reactome:R-HSA-5654618|Reactome:R-HSA-380073|Reactome:R-HSA-389348|Reactome:R-HSA-5686071|Reactome:R-HSA-3928592|Reactome:R-HSA-5686318|Reactome:R-HSA-1433471|Reactome:R-HSA-1225957|Reactome:R-HSA-4093336|Reactome:R-HSA-8851899|Reactome:R-HSA-1433415|Reactome:R-HSA-8853307|Reactome:R-HSA-114544|Reactome:R-HSA-9672170|Reactome:R-HSA-1168636|Reactome:R-HSA-9640167|Reactome:R-HSA-170979|Reactome:R-HSA-354173|Reactome:R-HSA-8875320|Reactome:R-HSA-939265|Reactome:R-HSA-392054|Reactome:R-HSA-2485180|Reactome:R-HSA-1250498|Reactome:R-HSA-389350|Reactome:R-HSA-8875591|Reactome:R-HSA-1225951|Reactome:R-HSA-9619803|Reactome:R-HSA-8877760|Reactome:R-HSA-445064|Reactome:R-HSA-8876837|Reactome:R-HSA-205039|Reactome:R-HSA-379044|Reactome:R-HSA-428750|Reactome:R-HSA-8848618|Reactome:R-HSA-5654413|Reactome:R-HSA-203977|Reactome:R-HSA-9665404|Reactome:R-HSA-194518|Reactome:R-HSA-392195|Reactome:R-HSA-3928651|Reactome:R-HSA-6811418|Reactome:R-HSA-8875568|Reactome:R-HSA-5654663|Reactome:R-HSA-9634418|Reactome:R-HSA-428535|Reactome:R-HSA-8875318|Reactome:R-HSA-8876615|Reactome:R-HSA-9624845|Reactome:R-HSA-177945|Reactome:R-HSA-416588|Reactome:R-HSA-6807868|Reactome:R-HSA-5654392|Reactome:R-HSA-442273|Reactome:R-HSA-8964604|Reactome:R-HSA-1250383|Reactome:R-HSA-5623508|Reactome:R-HSA-8877451|Reactome:R-HSA-749453|Reactome:R-HSA-2179407|Reactome:R-HSA-419166|Reactome:R-HSA-9665009|Reactome:R-HSA-3965444|Reactome:R-HSA-418579|Reactome:R-HSA-5694409|Reactome:R-HSA-8982640|Reactome:R-HSA-194913|Reactome:R-HSA-8877475 go-plus.json Rap guanyl-nucleotide exchange factor activity|GDS|guanyl-nucleotide release factor activity|Sar guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|RhoGEF|GNRP|GEF|cAMP-dependent guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho guanine nucleotide exchange factor|GDP-dissociation stimulator activity|Ral guanyl-nucleotide exchange factor activity|guanyl-nucleotide releasing factor|Ran guanyl-nucleotide exchange factor activity http://purl.obolibrary.org/obo/GO_0005085 goslim_chembl|goslim_yeast|goslim_drosophila GO:0005093 biolink:MolecularActivity Rab GDP-dissociation inhibitor activity Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding. go-plus.json http://purl.obolibrary.org/obo/GO_0005093 GO:0005094 biolink:MolecularActivity Rho GDP-dissociation inhibitor activity Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding. go-plus.json http://purl.obolibrary.org/obo/GO_0005094 GO:0005091 biolink:MolecularActivity guanyl-nucleotide exchange factor adaptor activity The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way. go-plus.json http://purl.obolibrary.org/obo/GO_0005091 GO:0005092 biolink:MolecularActivity GDP-dissociation inhibitor activity Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding. go-plus.json GDI http://purl.obolibrary.org/obo/GO_0005092 GO:0044658 biolink:BiologicalProcess pore formation in membrane of host by symbiont The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of a host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044658 GO:0044659 biolink:BiologicalProcess viral release from host cell by cytolysis The killing by a virus of a cell by means of the rupture of cell membranes and the loss of cytoplasm. VZ:1077 go-plus.json viral exit from host cell by cytolysis|cytolysis by virus of host cell|lytic viral release|lytic viral life cycle|viral release by host cell lysis|viral release by cell lysis http://purl.obolibrary.org/obo/GO_0044659 GO:0005090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005090 GO:0044656 biolink:BiologicalProcess regulation of post-lysosomal vacuole size Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis. go-plus.json regulation of post-lysosome size http://purl.obolibrary.org/obo/GO_0044656 GO:0044657 biolink:BiologicalProcess pore formation in membrane of other organism during symbiotic interaction The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044657 GO:0030024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030024 GO:0030025 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030025 GO:0030022 biolink:MolecularActivity obsolete adhesive extracellular matrix constituent OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix. go-plus.json adhesive extracellular matrix constituent http://purl.obolibrary.org/obo/GO_0030022 CHEBI:139588 biolink:ChemicalSubstance alpha-hydroxy ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_139588 GO:0030023 biolink:MolecularActivity extracellular matrix constituent conferring elasticity A component of the extracellular matrix that enables the matrix to recoil after transient stretching. go-plus.json core matrisome|core extracellular matrix|elastin http://purl.obolibrary.org/obo/GO_0030023 CHEBI:139589 biolink:ChemicalSubstance retinoid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139589 GO:0030020 biolink:MolecularActivity extracellular matrix structural constituent conferring tensile strength A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress. go-plus.json core matrisome|core extracellular matrix http://purl.obolibrary.org/obo/GO_0030020 GO:0030021 biolink:MolecularActivity extracellular matrix structural constituent conferring compression resistance A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan. go-plus.json core matrisome|core extracellular matrix http://purl.obolibrary.org/obo/GO_0030021 CHEBI:139583 biolink:ChemicalSubstance (R,R)-bis(2-oleoylglycero)-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139583 CHEBI:139585 biolink:ChemicalSubstance (R,R)-2-oleoylglycero-1-phospho-1'-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_139585 UBERON:0004264 biolink:AnatomicalEntity lower leg skin A zone of skin that is part of a lower leg [Automatically generated definition]. go-plus.json hind limb middle limb segment skin|hind limb zeugopod skin http://purl.obolibrary.org/obo/UBERON_0004264 UBERON:0004265 biolink:AnatomicalEntity outflow tract myocardium A myocardium that is part of a outflow tract [Automatically generated definition]. go-plus.json cardiac muscle of outflow tract|outflow tract cardiac muscle|heart myocardium of outflow tract|outflow tract muscle of heart|heart muscle of outflow tract|muscle of heart of outflow tract|outflow tract heart muscle|myocardium of outflow tract|outflow tract heart myocardium http://purl.obolibrary.org/obo/UBERON_0004265 UBERON:0004262 biolink:AnatomicalEntity upper leg skin A zone of skin that is part of a hindlimb stylopod [Automatically generated definition]. go-plus.json hind limb stylopod skin|skin of thigh|skin of upper leg|thigh skin|hindlimb stylopod skin http://purl.obolibrary.org/obo/UBERON_0004262 UBERON:0004263 biolink:AnatomicalEntity upper arm skin A zone of skin that is part of a forelimb stylopod [Automatically generated definition]. go-plus.json skin of arm stylopod|arm stylopod skin|skin of upper arm http://purl.obolibrary.org/obo/UBERON_0004263 UBERON:0004260 biolink:AnatomicalEntity upper arm blood vessel A blood vessel that is part of a forelimb stylopod [Automatically generated definition]. go-plus.json forelimb stylopod blood vessel http://purl.obolibrary.org/obo/UBERON_0004260 UBERON:0004261 biolink:AnatomicalEntity lower leg blood vessel A blood vessel that is part of a lower leg [Automatically generated definition]. go-plus.json hindlimb zeugopod blood vessel http://purl.obolibrary.org/obo/UBERON_0004261 UBERON:0004268 biolink:AnatomicalEntity lower arm connective tissue A portion of connective tissue that is part of a lower arm [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004268 UBERON:0004269 biolink:AnatomicalEntity upper arm connective tissue A portion of connective tissue that is part of a forelimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004269 UBERON:0004266 biolink:AnatomicalEntity upper leg connective tissue A portion of connective tissue that is part of a hindlimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004266 UBERON:0004267 biolink:AnatomicalEntity back connective tissue A portion of connective tissue that is part of a back [Automatically generated definition]. go-plus.json mesenchyne of back http://purl.obolibrary.org/obo/UBERON_0004267 CHEBI:33404 biolink:ChemicalSubstance 3-hydroxypropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33404 CHEBI:33405 biolink:ChemicalSubstance hydracid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33405 CHEBI:33406 biolink:ChemicalSubstance organoarsenic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33406 CHEBI:33407 biolink:ChemicalSubstance arsenic oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33407 CHEBI:33408 biolink:ChemicalSubstance pnictogen oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33408 CHEBI:33409 biolink:ChemicalSubstance methylarsonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33409 chebi_ph7_3 UBERON:0004253 biolink:AnatomicalEntity skin muscle Any muscle organ that is part of a skin of body [Automatically generated definition]. go-plus.json skin muscle organ|integumental system muscle|muscle of integumental system|muscle organ of skin http://purl.obolibrary.org/obo/UBERON_0004253 UBERON:0004254 biolink:AnatomicalEntity forelimb zeugopod muscle Any muscle organ that is part of a forelimb zeugopod (lower arm)[Automatically generated definition]. go-plus.json muscle of forearm|lower arm muscle|forearm muscle|wing zeugopod muscle http://purl.obolibrary.org/obo/UBERON_0004254 UBERON:0004251 biolink:AnatomicalEntity hindlimb zeugopod bone A bone that is part of a lower leg [Automatically generated definition]. go-plus.json bone of hindlimb middle limb segment|intermediate segment of free lower limb bone organ|bone of zeugopod of leg|zeugopod of hind limb bone|bone of hind limb zeugopod|bone organ of middle limb segment of hindlimb|bone of inferior member zeugopod|zeugopod of inferior member bone|bone of intermediate segment of free lower limb|zeugopod of leg bone organ|bone organ of zeugopod of hindlimb|middle limb segment of hindlimb bone|bone of lower leg|middle limb segment of hind limb bone|bone organ of zeugopod of inferior member|bone organ of middle limb segment of inferior member|middle limb segment of inferior member bone|bone organ of zeugopod of hind limb|bone organ of middle limb segment of hind limb|zeugopod of hindlimb bone|bone of inferior member middle limb segment|bone of hind limb middle limb segment|inferior member zeugopod bone organ|lower extremity middle limb segment bone|hind limb zeugopod bone organ|bone of hindlimb zeugopod|bone organ of zeugopod of lower extremity|hindlimb middle limb segment bone organ|zeugopod of lower extremity bone organ|bone organ of lower extremity zeugopod|bone organ of middle limb segment of lower extremity|hindlimb zeugopod bone|bone of lower extremity middle limb segment|hind limb middle limb segment bone|lower extremity zeugopod bone organ|middle limb segment of lower extremity bone organ|inferior member middle limb segment bone|bone organ of hindlimb middle limb segment|bone organ of hind limb zeugopod|zeugopod of hind limb bone organ|bone organ of inferior member zeugopod|zeugopod of inferior member bone organ|bone of middle limb segment of hindlimb|lower leg bone|intermediate segment of free lower limb bone|bone organ of zeugopod of leg|bone of zeugopod of inferior member|middle limb segment of hind limb bone organ|middle limb segment of hindlimb bone organ|bone organ of intermediate segment of free lower limb|bone of zeugopod of hind limb|middle limb segment of inferior member bone organ|zeugopod of leg bone|bone of zeugopod of hindlimb|bone organ of lower leg|bone of middle limb segment of inferior member|zeugopod of hindlimb bone organ|lower extremity middle limb segment bone organ|bone of middle limb segment of hind limb|bone organ of inferior member middle limb segment|bone of zeugopod of lower extremity|bone organ of hind limb middle limb segment|inferior member zeugopod bone|hind limb zeugopod bone|bone organ of hindlimb zeugopod|hindlimb zeugopod bone organ|hindlimb middle limb segment bone|bone of lower extremity zeugopod|bone of middle limb segment of lower extremity|zeugopod of lower extremity bone|hind limb middle limb segment bone organ|inferior member middle limb segment bone organ|bone organ of lower extremity middle limb segment|middle limb segment of lower extremity bone|lower extremity zeugopod bone http://purl.obolibrary.org/obo/UBERON_0004251 UBERON:0004252 biolink:AnatomicalEntity hindlimb stylopod muscle Any muscle organ that is part of a hindlimb stylopod (upper leg)[Automatically generated definition]. go-plus.json upper leg muscle|muscle of thigh|thigh muscle http://purl.obolibrary.org/obo/UBERON_0004252 UBERON:0004250 biolink:AnatomicalEntity upper arm bone A bone that is part of a forelimb stylopod [Automatically generated definition]. go-plus.json humerus http://purl.obolibrary.org/obo/UBERON_0004250 CHEBI:33402 biolink:ChemicalSubstance sulfur oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33402 CHEBI:33403 biolink:ChemicalSubstance elemental sulfur go-plus.json http://purl.obolibrary.org/obo/CHEBI_33403 UBERON:0004259 biolink:AnatomicalEntity lower arm blood vessel A blood vessel that is part of a lower arm [Automatically generated definition]. go-plus.json forelimb zeugopod blood vessel http://purl.obolibrary.org/obo/UBERON_0004259 UBERON:0004257 biolink:AnatomicalEntity upper leg blood vessel A blood vessel that is part of a hindlimb stylopod [Automatically generated definition]. go-plus.json thigh blood vessel|blood vessel of stylopod of hind limb|blood vessel of stylopod of hindlimb|hindlimb stylopod blood vessel|blood vessel of thigh|hind limb stylopod blood vessel|blood vessel of upper leg http://purl.obolibrary.org/obo/UBERON_0004257 UBERON:0004258 biolink:AnatomicalEntity back blood vessel A blood vessel that is part of a back [Automatically generated definition]. go-plus.json blood vessel of back http://purl.obolibrary.org/obo/UBERON_0004258 UBERON:0004255 biolink:AnatomicalEntity forelimb stylopod muscle Any muscle organ that is part of a forelimb stylopod (upper arm)[Automatically generated definition]. go-plus.json muscle of upper arm|muscle of arm|wing stylopod muscle|skeletal muscle of upper arm|upper arm muscle http://purl.obolibrary.org/obo/UBERON_0004255 UBERON:0004256 biolink:AnatomicalEntity hindlimb zeugopod muscle Any muscle organ that is part of a hindlimb zeugopod (lower leg) [Automatically generated definition]. go-plus.json lower leg muscle|calf muscle|muscle of leg http://purl.obolibrary.org/obo/UBERON_0004256 UBERON:0004242 biolink:AnatomicalEntity bronchus smooth muscle A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]. go-plus.json bronchi smooth muscle|bronchial trunk smooth muscle|involuntary muscle of bronchi|involuntary muscle of bronchial trunk|involuntary muscle of bronchus|bronchus smooth muscle tissue|bronchial trunk smooth muscle tissue|bronchi smooth muscle tissue|smooth muscle tissue of bronchi|smooth muscle of bronchi|smooth muscle tissue of bronchial trunk|smooth muscle of bronchial trunk|non-striated muscle of bronchi|non-striated muscle of bronchial trunk|bronchus involuntary muscle|bronchial trunk involuntary muscle|non-striated muscle of bronchus|bronchi involuntary muscle|smooth muscle of bronchus|bronchial smooth muscle|smooth muscle tissue of bronchus|bronchi non-striated muscle|bronchial trunk non-striated muscle|bronchus non-striated muscle http://purl.obolibrary.org/obo/UBERON_0004242 UBERON:0004243 biolink:AnatomicalEntity prostate gland smooth muscle A portion of smooth muscle tissue that is part of a prostate gland [Automatically generated definition]. go-plus.json involuntary muscle of prostate gland|non-striated muscle of prostate|prostate involuntary muscle|muscular tissue of prostate|substantia muscularis prostatae|smooth muscle of prostate|smooth muscle tissue of prostate|prostate gland smooth muscle tissue|prostate non-striated muscle|prostate smooth muscle|non-striated muscle of prostate gland|involuntary muscle of prostate|smooth muscle of prostate gland|smooth muscle tissue of prostate gland|prostate gland involuntary muscle|prostate smooth muscle tissue|prostate gland non-striated muscle http://purl.obolibrary.org/obo/UBERON_0004243 UBERON:0004240 biolink:AnatomicalEntity gall bladder smooth muscle A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]. go-plus.json gallbladder non-striated muscle|non-striated muscle of gall bladder|gallbladder smooth muscle|gallbladder involuntary muscle|involuntary muscle of gallbladder|smooth muscle of gall bladder|smooth muscle tissue of gall bladder|gall bladder non-striated muscle|gall bladder smooth muscle tissue|biliary smooth muscle|smooth muscle tissue of gallbladder|smooth muscle of gallbladder|involuntary muscle of gall bladder|non-striated muscle of gallbladder|gallbladder smooth muscle tissue|gall bladder involuntary muscle http://purl.obolibrary.org/obo/UBERON_0004240 UBERON:0004248 biolink:AnatomicalEntity pedal digit bone A bone that is part of a hindlimb digit. Typically phalanges but may include sesamoids. go-plus.json foot digit bone organ|toe bone|bone of digit of foot|digitus pedis bone organ|foot digit bone|toe bone organ|digital bone of pes|foot digit bone|digital bone of foot|digit of foot bone|digitus pedis bone|hind limb digit bone http://purl.obolibrary.org/obo/UBERON_0004248 UBERON:0004249 biolink:AnatomicalEntity manual digit bone A bone that is part of a forelimb digit. Typically phalanges but may include sesamoids. go-plus.json finger bone|hand digit bone|hand digit bone|digital bone of hand|digital bone of manus|fore limb digit bone http://purl.obolibrary.org/obo/UBERON_0004249 UBERON:0004246 biolink:AnatomicalEntity outflow tract smooth muscle A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]. go-plus.json outflow tract non-striated muscle|outflow tract smooth muscle tissue|involuntary muscle of outflow tract|outflow tract involuntary muscle|smooth muscle tissue of outflow tract|smooth muscle of outflow tract|non-striated muscle of outflow tract http://purl.obolibrary.org/obo/UBERON_0004246 UBERON:0004247 biolink:AnatomicalEntity bone of dorsum A bone that is part of the dorsal region of an animal. go-plus.json back bone|bone of back|dorsal region bone http://purl.obolibrary.org/obo/UBERON_0004247 UBERON:0004245 biolink:AnatomicalEntity oviduct smooth muscle A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]. go-plus.json non-striated muscle of fallopian tube|fallopian tube smooth muscle tissue|smooth muscle of fallopian tube|smooth muscle tissue of fallopian tube|fallopian tube non-striated muscle|fallopian tube smooth muscle|fallopian tube involuntary muscle|involuntary muscle of fallopian tube http://purl.obolibrary.org/obo/UBERON_0004245 UBERON:0004231 biolink:AnatomicalEntity anal region smooth muscle A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]. go-plus.json anal region smooth muscle tissue|anal part of perineum non-striated muscle|anal triangle involuntary muscle|smooth muscle tissue of anal triangle|smooth muscle of anal triangle|anal region non-striated muscle|anal part of perineum smooth muscle tissue|anal part of perineum smooth muscle|non-striated muscle of anal triangle|involuntary muscle of anal part of perineum|involuntary muscle of anal region|anal region involuntary muscle|anal triangle non-striated muscle|anal part of perineum involuntary muscle|smooth muscle tissue of anal part of perineum|smooth muscle of anal part of perineum|anal triangle smooth muscle|anal triangle smooth muscle tissue|smooth muscle tissue of anal region|involuntary muscle of anal triangle|smooth muscle of anal region|non-striated muscle of anal part of perineum|non-striated muscle of anal region http://purl.obolibrary.org/obo/UBERON_0004231 UBERON:0004232 biolink:AnatomicalEntity lymphatic vessel smooth muscle A portion of smooth muscle tissue that is part of a lymphatic vessel [Automatically generated definition]. go-plus.json smooth muscle of lymph vessel|smooth muscle tissue of lymph vessel|lymph vessel non-striated muscle|lymphatic vessel involuntary muscle|lymph vessel smooth muscle tissue|lymph vessel smooth muscle|non-striated muscle of lymphatic vessel|involuntary muscle of lymph vessel|smooth muscle of lymphatic vessel|smooth muscle tissue of lymphatic vessel|lymphatic vessel non-striated muscle|lymph vessel involuntary muscle|lymphatic vessel smooth muscle tissue|involuntary muscle of lymphatic vessel|non-striated muscle of lymph vessel http://purl.obolibrary.org/obo/UBERON_0004232 UBERON:0004230 biolink:AnatomicalEntity urinary bladder neck smooth muscle A portion of smooth muscle tissue that is part of a neck of urinary bladder [Automatically generated definition]. go-plus.json neck of urinary bladder non-striated muscle|bladder neck smooth muscle tissue|smooth muscle of bladder neck|smooth muscle tissue of bladder neck|neck of bladder smooth muscle tissue|non-striated muscle of vesical neck|non-striated muscle of urinary bladder neck|neck of urinary bladder smooth muscle|involuntary muscle of neck of urinary bladder|neck of bladder non-striated muscle|smooth muscle of vesical neck|bladder neck non-striated muscle|urinary bladder neck involuntary muscle|smooth muscle of urinary bladder neck|smooth muscle tissue of vesical neck|neck of urinary bladder smooth muscle tissue|vesical neck involuntary muscle|smooth muscle tissue of urinary bladder neck|neck of bladder smooth muscle|bladder neck smooth muscle|vesical neck non-striated muscle|involuntary muscle of neck of bladder|urinary bladder neck muscle|urinary bladder neck non-striated muscle|bladder neck involuntary muscle|neck of bladder involuntary muscle|involuntary muscle of bladder neck|vesical neck smooth muscle|smooth muscle tissue of neck of urinary bladder|smooth muscle of neck of urinary bladder|trigonal muscle of urinary bladder|involuntary muscle of vesical neck|involuntary muscle of urinary bladder neck|neck of urinary bladder involuntary muscle|non-striated muscle of neck of urinary bladder|smooth muscle tissue of neck of bladder|smooth muscle of neck of bladder|urinary bladder neck smooth muscle tissue|non-striated muscle of neck of bladder|vesical neck smooth muscle tissue|non-striated muscle of bladder neck|trigonal muscle http://purl.obolibrary.org/obo/UBERON_0004230 UBERON:0004239 biolink:AnatomicalEntity small intestine smooth muscle A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]. go-plus.json smooth muscle tissue of small bowel|smooth muscle of small bowel|small bowel smooth muscle tissue|non-striated muscle of small bowel|small intestine involuntary muscle|smooth muscle tissue of small intestine|smooth muscle of small intestine|non-striated muscle of small intestine|small bowel non-striated muscle|small bowel involuntary muscle|small bowel smooth muscle|involuntary muscle of small bowel|small intestine non-striated muscle|small intestine smooth muscle tissue|involuntary muscle of small intestine http://purl.obolibrary.org/obo/UBERON_0004239 UBERON:0004237 biolink:AnatomicalEntity blood vessel smooth muscle smooth muscle found within, and composing the majority of the wall of blood vessels. go-plus.json non-striated muscle of blood vessel|smooth muscle of blood vessel|smooth muscle tissue of blood vessel|vascular smooth muscle|blood vessel smooth muscle tissue|blood vessel non-striated muscle|vascular smooth muscle tissue|involuntary muscle of blood vessel|blood vessel involuntary muscle http://purl.obolibrary.org/obo/UBERON_0004237 UBERON:0004238 biolink:AnatomicalEntity spleen smooth muscle A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]. go-plus.json smooth muscle of spleen|smooth muscle tissue of spleen|spleen non-striated muscle|spleen smooth muscle tissue|involuntary muscle of spleen|spleen involuntary muscle|non-striated muscle of spleen http://purl.obolibrary.org/obo/UBERON_0004238 UBERON:0004235 biolink:AnatomicalEntity mammary gland smooth muscle A portion of smooth muscle tissue that is part of a mammary gland [Automatically generated definition]. go-plus.json smooth muscle tissue of mammary gland http://purl.obolibrary.org/obo/UBERON_0004235 UBERON:0004236 biolink:AnatomicalEntity arteriole smooth muscle A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004236 UBERON:0004233 biolink:AnatomicalEntity lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]. go-plus.json lower respiratory tract non-striated muscle|lower respiratory tract smooth muscle tissue|involuntary muscle of lower respiratory tract|lower respiratory tract involuntary muscle|smooth muscle tissue of lower respiratory tract|smooth muscle of lower respiratory tract|non-striated muscle of lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0004233 UBERON:0004234 biolink:AnatomicalEntity iris smooth muscle A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]. go-plus.json non-striated muscle of iris|iris involuntary muscle|smooth muscle of iris|smooth muscle tissue of iris|iris non-striated muscle|iridial smooth muscle|involuntary muscle of iris|iris smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004234 UBERON:0004290 biolink:AnatomicalEntity dermomyotome The bilaminar epithelium formed from the myotome and dermatome. go-plus.json dermamyotome|dermomyotomes http://purl.obolibrary.org/obo/UBERON_0004290 UBERON:0004297 biolink:AnatomicalEntity respiratory system blood vessel smooth muscle A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. go-plus.json smooth muscle tissue of blood vessel of respiratory system http://purl.obolibrary.org/obo/UBERON_0004297 UBERON:0004295 biolink:AnatomicalEntity sympathetic nerve trunk A nerve trunk that is part of a sympathetic nervous system [Automatically generated definition]. go-plus.json nerve trunk of sympathetic nervous system|nerve trunk of sympathetic part of autonomic division of nervous system|sympathetic nervous system nerve trunk http://purl.obolibrary.org/obo/UBERON_0004295 UBERON:0004296 biolink:AnatomicalEntity respiratory system lymphatic vessel smooth muscle A lymphatic vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. go-plus.json smooth muscle of lymph vessel of respiratory system http://purl.obolibrary.org/obo/UBERON_0004296 UBERON:0004293 biolink:AnatomicalEntity parasympathetic nerve A nerve that is part of a parasympathetic nervous system [Automatically generated definition]. go-plus.json nerve of parasympathetic nervous system http://purl.obolibrary.org/obo/UBERON_0004293 UBERON:0004294 biolink:AnatomicalEntity glomerular capillary endothelium An endothelium that is part of a glomerular capillary. go-plus.json renal glomerulus capillary endothelium http://purl.obolibrary.org/obo/UBERON_0004294 PR:000008942 biolink:Protein insulin-like growth factor II A protein that is a translation product of the human IGF2 gene or a 1:1 ortholog thereof. go-plus.json multiplication-stimulating polypeptide|IGF2|Igf-2|IGF-II|somatomedin-A http://purl.obolibrary.org/obo/PR_000008942 UBERON:0004291 biolink:AnatomicalEntity heart rudiment A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. go-plus.json heart cone|rudimentary heart http://purl.obolibrary.org/obo/UBERON_0004291 UBERON:0004292 biolink:AnatomicalEntity cardiac skeleton Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart. go-plus.json trigonum fibrosum dextrum cordis|cardiac fibrous skeleton|anulus fibrosus sinister cordis|skeleton of heart|trigonum fibrosum sinistrum cordis|heart fibrous skeleton|anulus fibrosus dexter cordis|trigona fibrosa|fibrous skeleton of heart http://purl.obolibrary.org/obo/UBERON_0004292 PR:000008910 biolink:Protein interferon-induced helicase C domain-containing protein 1 A protein that is a translation product of the human IFIH1 gene or a 1:1 ortholog thereof. go-plus.json MDA5|melanoma differentiation-associated protein 5|interferon-induced with helicase C domain protein 1|RH116|murabutide down-regulated protein|IFIH1|MDA-5|helicase with 2 CARD domains|RNA helicase-DEAD box protein 116|interferon induced with helicase C domain protein 1|helicard http://purl.obolibrary.org/obo/PR_000008910 UBERON:0004288 biolink:AnatomicalEntity skeleton Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. go-plus.json set of bones of body|set of all bones http://purl.obolibrary.org/obo/UBERON_0004288 UBERON:0004275 biolink:AnatomicalEntity third ventricle choroid plexus epithelium A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition]. go-plus.json third ventricle epithelium of chorioid plexus of cerebral hemisphere|third ventricle choroid plexus epithelial tissue|third ventricle chorioid plexus of cerebral hemisphere epithelial tissue|chorioid plexus of cerebral hemisphere epithelial tissue of third ventricle|choroid plexus epithelial tissue of third ventricle|third ventricle chorioid plexus of cerebral hemisphere epithelium|third ventricle epithelial tissue of choroid plexus|epithelium of chorioid plexus of cerebral hemisphere of third ventricle|third ventricle epithelial tissue of chorioid plexus of cerebral hemisphere|epithelial tissue of chorioid plexus of cerebral hemisphere of third ventricle|epithelium of choroid plexus of third ventricle|choroid plexus epithelium of third ventricle|epithelial tissue of choroid plexus of third ventricle|chorioid plexus of cerebral hemisphere epithelium of third ventricle|third ventricle epithelium of choroid plexus http://purl.obolibrary.org/obo/UBERON_0004275 UBERON:0004276 biolink:AnatomicalEntity fourth ventricle choroid plexus epithelium A choroid plexus epithelium that is part of a fourth ventricle [Automatically generated definition]. go-plus.json chorioid plexus of cerebral hemisphere epithelium of fourth ventricle|fourth ventricle epithelium of choroid plexus|epithelial tissue of choroid plexus of fourth ventricle|choroid plexus epithelium of fourth ventricle|fourth ventricle epithelium of chorioid plexus of cerebral hemisphere|epithelial tissue of chorioid plexus of cerebral hemisphere of fourth ventricle|epithelium of choroid plexus of fourth ventricle|epithelium of chorioid plexus of cerebral hemisphere of fourth ventricle|fourth ventricle choroid plexus epithelial tissue|fourth ventricle chorioid plexus of cerebral hemisphere epithelial tissue|fourth ventricle chorioid plexus of cerebral hemisphere epithelium|fourth ventricle epithelial tissue of choroid plexus|choroid plexus epithelial tissue of fourth ventricle|fourth ventricle epithelial tissue of chorioid plexus of cerebral hemisphere|chorioid plexus of cerebral hemisphere epithelial tissue of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0004276 UBERON:0004273 biolink:AnatomicalEntity cartilaginous joint suture A cranial suture that is part of a cartilaginous joint [Automatically generated definition]. go-plus.json articulatio cartilaginea suture of cranium|cranial suture of cartilaginous joint|articulatio cartilaginea cranial suture|cartilaginous joint cranial sutures set|cartilaginous joint cranial sutures|cranial sutures set of articulatio cartilaginea|cranial sutures of articulatio cartilaginea|suture of cranium of cartilaginous joint|cranium suture of articulatio cartilaginea|cartilaginous joint cranial suture|articulatio cartilaginea cranium suture|articulatio cartilaginea cranial sutures set|articulatio cartilaginea cranial sutures|cartilaginous joint suture of cranium|cranium suture of cartilaginous joint|suture of cranium of articulatio cartilaginea|cranial sutures of cartilaginous joint|cranial sutures set of cartilaginous joint|cartilaginous joint cranium suture|cranial suture of articulatio cartilaginea http://purl.obolibrary.org/obo/UBERON_0004273 UBERON:0004274 biolink:AnatomicalEntity lateral ventricle choroid plexus epithelium A choroid plexus epithelium that is part of a lateral ventricle [Automatically generated definition]. go-plus.json lateral ventricle epithelial tissue of chorioid plexus of cerebral hemisphere|epithelium of choroid plexus of lateral ventricle|epithelial tissue of chorioid plexus of cerebral hemisphere of lateral ventricle|choroid plexus epithelium of lateral ventricle|epithelial tissue of choroid plexus of lateral ventricle|chorioid plexus of cerebral hemisphere epithelium of lateral ventricle|lateral ventricle epithelium of choroid plexus|lateral ventricle epithelium of chorioid plexus of cerebral hemisphere|lateral ventricle choroid plexus epithelial tissue|lateral ventricle chorioid plexus of cerebral hemisphere epithelial tissue|chorioid plexus of cerebral hemisphere epithelial tissue of lateral ventricle|choroid plexus epithelial tissue of lateral ventricle|lateral ventricle chorioid plexus of cerebral hemisphere epithelium|lateral ventricle epithelial tissue of choroid plexus|epithelium of chorioid plexus of cerebral hemisphere of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0004274 UBERON:0004271 biolink:AnatomicalEntity outflow tract pericardium A pericardium that is part of a outflow tract [Automatically generated definition]. go-plus.json pericardium of outflow tract http://purl.obolibrary.org/obo/UBERON_0004271 UBERON:0004270 biolink:AnatomicalEntity lower leg connective tissue A portion of connective tissue that is part of a lower leg [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004270 UBERON:0004277 biolink:AnatomicalEntity eye muscle A muscle that is part of the eye region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004277 GO:0019618 biolink:BiologicalProcess protocatechuate catabolic process, ortho-cleavage The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate. MetaCyc:PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY go-plus.json 3,4-dihydroxybenzoate catabolic process, ortho-cleavage|protocatechuate degradation, ortho-cleavage|protocatechuate breakdown, ortho-cleavage|protocatechuate catabolic process to beta-ketoadipate http://purl.obolibrary.org/obo/GO_0019618 CHEBI:57440 biolink:ChemicalSubstance N-ethylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57440 chebi_ph7_3 GO:0019619 biolink:BiologicalProcess 3,4-dihydroxybenzoate catabolic process The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate. go-plus.json protocatechuate degradation|protocatechuate breakdown|protocatechuate catabolic process|protocatechuate catabolism http://purl.obolibrary.org/obo/GO_0019619 CHEBI:57441 biolink:ChemicalSubstance 2,3-diketogulonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57441 chebi_ph7_3 GO:0019616 biolink:BiologicalProcess catechol catabolic process, meta-cleavage The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom. MetaCyc:P183-PWY go-plus.json catechol degradation, meta-cleavage|catechol breakdown, meta-cleavage http://purl.obolibrary.org/obo/GO_0019616 GO:0019617 biolink:BiologicalProcess protocatechuate catabolic process, meta-cleavage The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate. MetaCyc:P184-PWY go-plus.json protocatechuate breakdown, meta-cleavage|protocatechuate degradation, meta-cleavage|3,4-dihydroxybenzoate catabolic process, meta-cleavage|protocatechuate catabolic process to oxaloacetate and pyruvate http://purl.obolibrary.org/obo/GO_0019617 GO:0019614 biolink:BiologicalProcess catechol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. go-plus.json catechol catabolic process|catechol catabolism|catechol degradation|catechol breakdown http://purl.obolibrary.org/obo/GO_0019614 GO:0019615 biolink:BiologicalProcess catechol catabolic process, ortho-cleavage The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups. MetaCyc:CATECHOL-ORTHO-CLEAVAGE-PWY go-plus.json catechol breakdown, ortho-cleavage|catechol degradation, ortho-cleavage http://purl.obolibrary.org/obo/GO_0019615 GO:0019612 biolink:BiologicalProcess 4-toluenecarboxylate catabolic process The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule. MetaCyc:4TOLCARBDEG-PWY go-plus.json 4-toluenecarboxylate breakdown|4-toluenecarboxylate catabolism|p-toluate catabolism|4-toluenecarboxylate degradation|p-toluate catabolic process http://purl.obolibrary.org/obo/GO_0019612 GO:0019613 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019613 NCBITaxon:1643688 biolink:OrganismalEntity Leptospirales go-plus.json Leptospiriales http://purl.obolibrary.org/obo/NCBITaxon_1643688 CHEBI:57448 biolink:ChemicalSubstance (5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57448 chebi_ph7_3 GO:0019610 biolink:BiologicalProcess 3-hydroxyphenylacetate catabolic process The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate. MetaCyc:3-HYDROXYPHENYLACETATE-DEGRADATION-PWY go-plus.json 3-hydroxyphenylacetate degradation|3-hydroxyphenylacetate catabolism|3-hydroxyphenylacetate breakdown http://purl.obolibrary.org/obo/GO_0019610 GO:0019611 biolink:BiologicalProcess 4-toluenecarboxylate metabolic process The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule. go-plus.json 4-toluenecarboxylate metabolism|p-toluate metabolism|p-toluate metabolic process http://purl.obolibrary.org/obo/GO_0019611 CHEBI:57449 biolink:ChemicalSubstance (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57449 chebi_ph7_3 CHEBI:57446 biolink:ChemicalSubstance 15(S)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57446 chebi_ph7_3 CHEBI:57447 biolink:ChemicalSubstance 8(R)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57447 chebi_ph7_3 CHEBI:57444 biolink:ChemicalSubstance 12(S)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57444 chebi_ph7_3 CHEBI:57445 biolink:ChemicalSubstance thromboxane A2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57445 chebi_ph7_3 CHEBI:57442 biolink:ChemicalSubstance (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57442 chebi_ph7_3 CHEBI:57443 biolink:ChemicalSubstance S-adenosylmethioninaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57443 chebi_ph7_3 CHEBI:57439 biolink:ChemicalSubstance (3Z)-phytochromobilin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57439 chebi_ph7_3 CHEBI:139605 biolink:ChemicalSubstance O(3)-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139605 chebi_ph7_3 CHEBI:33484 biolink:ChemicalSubstance chalcogen oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33484 GO:0019629 biolink:BiologicalProcess propionate catabolic process, 2-methylcitrate cycle The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle. go-plus.json propionate breakdown, 2-methylcitrate cycle|propionate degradation, 2-methylcitrate cycle http://purl.obolibrary.org/obo/GO_0019629 CHEBI:57430 biolink:ChemicalSubstance (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57430 chebi_ph7_3 CHEBI:33485 biolink:ChemicalSubstance chalcogen oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33485 GO:0019627 biolink:BiologicalProcess urea metabolic process The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2. go-plus.json urea metabolism http://purl.obolibrary.org/obo/GO_0019627 CHEBI:139607 biolink:ChemicalSubstance O(3)-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139607 chebi_ph7_3 GO:0019628 biolink:BiologicalProcess urate catabolic process The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine. MetaCyc:P165-PWY go-plus.json urate degradation|urate catabolism|urate breakdown|uric acid catabolic process http://purl.obolibrary.org/obo/GO_0019628 CHEBI:33488 biolink:ChemicalSubstance selenium oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33488 GO:0019625 biolink:BiologicalProcess atrazine catabolic process to cyanuric acid The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid. MetaCyc:P141-PWY go-plus.json atrazine breakdown to cyanuric acid|atrazine degradation to cyanuric acid http://purl.obolibrary.org/obo/GO_0019625 GO:0019626 biolink:BiologicalProcess short-chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6. MetaCyc:ACETOACETATE-DEG-PWY go-plus.json short-chain fatty acid degradation|short-chain fatty acid breakdown|short-chain fatty acid catabolism http://purl.obolibrary.org/obo/GO_0019626 CHEBI:33489 biolink:ChemicalSubstance selenium oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33489 GO:0019623 biolink:BiologicalProcess atrazine catabolic process to urea The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea. go-plus.json atrazine degradation to urea|atrazine breakdown to urea http://purl.obolibrary.org/obo/GO_0019623 CHEBI:139604 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_139604 chebi_ph7_3 GO:0019624 biolink:BiologicalProcess atrazine catabolic process to isopropylamine The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine. go-plus.json atrazine degradation to isopropylamine|atrazine breakdown to isopropylamine http://purl.obolibrary.org/obo/GO_0019624 GO:0019621 biolink:BiologicalProcess creatinine catabolic process to formate The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate. MetaCyc:CRNFORCAT-PWY go-plus.json creatinine breakdown to formate|creatinine degradation to formate http://purl.obolibrary.org/obo/GO_0019621 CHEBI:57437 biolink:ChemicalSubstance (2R,3Z)-phycocyanobilin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57437 chebi_ph7_3 CHEBI:57438 biolink:ChemicalSubstance (3Z)-phycoerythrobilin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57438 chebi_ph7_3 GO:0019622 biolink:BiologicalProcess 3-(3-hydroxy)phenylpropionate catabolic process The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate. MetaCyc:HCAMHPDEG-PWY go-plus.json 3-(3-hydroxy)phenylpropionate catabolism|3-(3-hydroxy)phenylpropionate degradation|3-(3-hydroxy)phenylpropionate breakdown http://purl.obolibrary.org/obo/GO_0019622 CHEBI:57435 biolink:ChemicalSubstance (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57435 chebi_ph7_3 GO:0019620 biolink:BiologicalProcess aerobic benzoate metabolic process The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen. go-plus.json aerobic benzoate metabolism http://purl.obolibrary.org/obo/GO_0019620 CHEBI:57436 biolink:ChemicalSubstance (3S,5S)-3,5-diammoniohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57436 chebi_ph7_3 CHEBI:139600 biolink:ChemicalSubstance calcitriol 25-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139600 CHEBI:57433 biolink:ChemicalSubstance sarcosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57433 chebi_ph7_3 CHEBI:57434 biolink:ChemicalSubstance (3S)-3,6-diammoniohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57434 chebi_ph7_3 CHEBI:57431 biolink:ChemicalSubstance N-(ammoniomethyl)urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_57431 chebi_ph7_3 CHEBI:33482 biolink:ChemicalSubstance sulfur oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33482 CHEBI:57432 biolink:ChemicalSubstance gibberellin A12 aldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57432 chebi_ph7_3 CHEBI:33483 biolink:ChemicalSubstance trithionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33483 CHEBI:57428 biolink:ChemicalSubstance (3R)-beta-leucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57428 chebi_ph7_3 CHEBI:57429 biolink:ChemicalSubstance (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57429 chebi_ph7_3 CHEBI:33459 biolink:ChemicalSubstance pnictogen oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33459 CHEBI:33452 biolink:ChemicalSubstance benzylic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33452 CHEBI:33455 biolink:ChemicalSubstance nitrogen oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33455 CHEBI:33456 biolink:ChemicalSubstance organoheteryl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33456 CHEBI:33457 biolink:ChemicalSubstance phosphorus oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33457 CHEBI:33458 biolink:ChemicalSubstance nitrogen oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33458 CHEBI:57426 biolink:ChemicalSubstance sinapoyl (S)-malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57426 chebi_ph7_3 CHEBI:57427 biolink:ChemicalSubstance L-leucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57427 chebi_ph7_3 CHEBI:57424 biolink:ChemicalSubstance (R)-3,3-dimethylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57424 chebi_ph7_3 CHEBI:57425 biolink:ChemicalSubstance 3-ethylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57425 chebi_ph7_3 CHEBI:57422 biolink:ChemicalSubstance (2R,3S)-2,3-dimethylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57422 chebi_ph7_3 CHEBI:57423 biolink:ChemicalSubstance (R)-2-ethylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57423 chebi_ph7_3 CHEBI:57421 biolink:ChemicalSubstance (2E,6E,10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57421 chebi_ph7_3 NCBITaxon:6020 biolink:OrganismalEntity Oligohymenophorea go-plus.json Holotricha|Oligohymenophorans|Oligohymenophora http://purl.obolibrary.org/obo/NCBITaxon_6020 CHEBI:57417 biolink:ChemicalSubstance 2,3-dihydroxybenzoyl 5'-adenylate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57417 chebi_ph7_3 CHEBI:57418 biolink:ChemicalSubstance (2-aminoethyl)phosphonic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57418 chebi_ph7_3 GO:0019609 biolink:BiologicalProcess 3-hydroxyphenylacetate metabolic process The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate. go-plus.json 3-hydroxyphenylacetate metabolism|3HPA metabolic process|3HPA metabolism http://purl.obolibrary.org/obo/GO_0019609 CHEBI:33462 biolink:ChemicalSubstance phosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33462 chebi_ph7_3 GO:0019607 biolink:BiologicalProcess phenylethylamine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds. MetaCyc:2PHENDEG-PWY go-plus.json phenylethylamine breakdown|phenylethylamine catabolism|phenylethylamine degradation http://purl.obolibrary.org/obo/GO_0019607 GO:0019608 biolink:BiologicalProcess nicotine catabolic process The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. MetaCyc:P181-PWY|UM-BBD_pathwayID:nic go-plus.json nicotine catabolism|nicotine degradation|nicotine breakdown http://purl.obolibrary.org/obo/GO_0019608 GO:0019605 biolink:BiologicalProcess butyrate metabolic process The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid. go-plus.json butyrate metabolism|butyric acid metabolic process|butanoic acid metabolism|butanoic acid metabolic process|butyric acid metabolism http://purl.obolibrary.org/obo/GO_0019605 GO:0019606 biolink:BiologicalProcess 2-oxobutyrate catabolic process The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2. MetaCyc:2OXOBUTYRATECAT-PWY go-plus.json alpha-ketobutyrate catabolic process|alpha-ketobutyrate catabolism|2-oxobutyrate catabolism|2-oxobutyrate degradation|2-oxobutyrate breakdown http://purl.obolibrary.org/obo/GO_0019606 CHEBI:33465 biolink:ChemicalSubstance elemental pnictogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33465 GO:0019603 biolink:BiologicalProcess toluene oxidation via 4-hydroxytoluene The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol). MetaCyc:TOLUENE-DEG-4-OH-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019603 GO:0019604 biolink:BiologicalProcess toluene oxidation to catechol The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2). UM-BBD_pathwayID:tol|MetaCyc:TOLUENE-DEG-CATECHOL-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019604 GO:0019601 biolink:BiologicalProcess toluene oxidation via 2-hydroxytoluene The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol). MetaCyc:TOLUENE-DEG-2-OH-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019601 GO:0019602 biolink:BiologicalProcess toluene oxidation via 3-hydroxytoluene The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol). MetaCyc:TOLUENE-DEG-3-OH-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019602 CHEBI:57415 biolink:ChemicalSubstance N-(carboxylatoaminomethyl)urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_57415 chebi_ph7_3 CHEBI:57416 biolink:ChemicalSubstance D-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57416 chebi_ph7_3 GO:0019600 biolink:BiologicalProcess toluene oxidation The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene. go-plus.json http://purl.obolibrary.org/obo/GO_0019600 CHEBI:57413 biolink:ChemicalSubstance (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57413 chebi_ph7_3 CHEBI:57414 biolink:ChemicalSubstance (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57414 chebi_ph7_3 CHEBI:57411 biolink:ChemicalSubstance (15Z)-12-oxophyto-10,15-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57411 chebi_ph7_3 CHEBI:57412 biolink:ChemicalSubstance (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57412 chebi_ph7_3 CHEBI:57410 biolink:ChemicalSubstance 15-oxo-ETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57410 chebi_ph7_3 CHEBI:33461 biolink:ChemicalSubstance phosphorus oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33461 RO:0002091 biolink:OntologyClass starts during RO:0002091 go-plus.json http://purl.obolibrary.org/obo/RO_0002091 RO:0002092 biolink:OntologyClass happens during RO:0002092 go-plus.json http://purl.obolibrary.org/obo/RO_0002092 RO:0002093 biolink:OntologyClass ends_during RO:0002093 go-plus.json http://purl.obolibrary.org/obo/RO_0002093 NCBITaxon:1329799 biolink:OrganismalEntity Archelosauria go-plus.json Archosauria-Testudines|Testudines + Archosauria group http://purl.obolibrary.org/obo/NCBITaxon_1329799 CHEBI:57408 biolink:ChemicalSubstance 15-dehydro-prostaglandin D2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57408 chebi_ph7_3 CHEBI:57409 biolink:ChemicalSubstance 15(S)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57409 chebi_ph7_3 UBERON:0004219 biolink:AnatomicalEntity urethra smooth muscle layer A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]. go-plus.json muscular layer of urethra|tunica muscularis urethrae|muscular coat of urethra|smooth muscle tissue of urethra|muscle layer of urethra|urethral smooth muscle|smooth muscle of urethra|urethra smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004219 CHEBI:57406 biolink:ChemicalSubstance prostaglandin D2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57406 chebi_ph7_3 RO:0002090 biolink:OntologyClass immediately_precedes RO:0002090 go-plus.json http://purl.obolibrary.org/obo/RO_0002090 CHEBI:57407 biolink:ChemicalSubstance 15-dehydro-prostaglandin I2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57407 chebi_ph7_3 CHEBI:33437 biolink:ChemicalSubstance chlorine oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33437 UBERON:0004220 biolink:AnatomicalEntity large intestine smooth muscle A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]. go-plus.json smooth muscle tissue of large intestine|smooth muscle of large intestine|non-striated muscle of large intestine|large intestine involuntary muscle|large intestine non-striated muscle|involuntary muscle of large intestine|large intestine smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004220 UBERON:0004221 biolink:AnatomicalEntity intestine smooth muscle A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]. go-plus.json non-striated muscle of intestine|intestine smooth muscle tissue|bowel non-striated muscle|bowel smooth muscle|involuntary muscle of bowel|bowel smooth muscle tissue|intestine non-striated muscle|intestine involuntary muscle|involuntary muscle of intestine|smooth muscle tissue of bowel|smooth muscle of bowel|intestinal smooth muscle|bowel involuntary muscle|non-striated muscle of bowel|smooth muscle tissue of intestine|intestinal muscularis|smooth muscle of intestine http://purl.obolibrary.org/obo/UBERON_0004221 CHEBI:33431 biolink:ChemicalSubstance elemental chlorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_33431 CHEBI:33432 biolink:ChemicalSubstance monoatomic chlorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_33432 CHEBI:33433 biolink:ChemicalSubstance monoatomic halogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33433 CHEBI:33434 biolink:ChemicalSubstance elemental halogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33434 UBERON:0004228 biolink:AnatomicalEntity urinary bladder smooth muscle A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]. go-plus.json smooth muscle tissue of urinary bladder|smooth muscle of urinary bladder|bladder smooth muscle tissue|non-striated muscle of urinary bladder|smooth muscle tissue of bladder|urinary bladder smooth muscle tissue|smooth muscle of bladder|non-striated muscle of bladder|bladder involuntary muscle|urinary bladder non-striated muscle|urinary bladder involuntary muscle|involuntary muscle of urinary bladder|bladder non-striated muscle|bladder smooth muscle|urinary bladder muscle|involuntary muscle of bladder|smooth muscle layer of bladder http://purl.obolibrary.org/obo/UBERON_0004228 CHEBI:57404 biolink:ChemicalSubstance prostaglandin F2alpha(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57404 chebi_ph7_3 CHEBI:57405 biolink:ChemicalSubstance prostaglandin H2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57405 chebi_ph7_3 CHEBI:57402 biolink:ChemicalSubstance 13,14-dihydro-15-oxo-prostaglandin E2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57402 chebi_ph7_3 UBERON:0004226 biolink:AnatomicalEntity gastrointestinal system smooth muscle A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]. go-plus.json smooth muscle tissue of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0004226 UBERON:0004227 biolink:AnatomicalEntity kidney pelvis smooth muscle the smooth muscle tissue surrounding the urothelium of the kidney pelvis go-plus.json pelvic smooth muscle|kidney pelvis smooth muscle|smooth muscle tissue of renal pelvis|renal pelvis smooth muscle http://purl.obolibrary.org/obo/UBERON_0004227 CHEBI:57403 biolink:ChemicalSubstance prostaglandin I2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57403 chebi_ph7_3 UBERON:0004224 biolink:AnatomicalEntity muscular coat of vas deferens A muscular coat that is part of a vas deferens [Automatically generated definition]. go-plus.json muscle layer of vas deferens|tunica muscularis ductus deferentis|muscular coat of ductus deferens|muscle layer of ductus deferens|tunica muscularis (ductus deferens)|muscularis of vas deferens|muscle layer of deferent duct|muscular layer of ductus deferens http://purl.obolibrary.org/obo/UBERON_0004224 CHEBI:57400 biolink:ChemicalSubstance 15-dehydro-prostaglandin E2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57400 chebi_ph7_3 CHEBI:57401 biolink:ChemicalSubstance 15-dehydro-prostaglandin E1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57401 chebi_ph7_3 UBERON:0004225 biolink:AnatomicalEntity respiratory system smooth muscle A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]. go-plus.json airway smooth muscle cell|smooth muscle of respiratory system|respiratory smooth muscle|airway smooth muscle http://purl.obolibrary.org/obo/UBERON_0004225 UBERON:0004222 biolink:AnatomicalEntity stomach smooth muscle A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]. go-plus.json smooth muscle tissue of stomach|non-striated muscle of ventriculus|smooth muscle of stomach|stomach smooth muscle tissue|gastric muscle|non-striated muscle of stomach|ventriculus smooth muscle tissue|ventriculus non-striated muscle|gastric smooth muscle|stomach involuntary muscle|ventriculus smooth muscle|stomach non-striated muscle|involuntary muscle of ventriculus|ventriculus involuntary muscle|involuntary muscle of stomach|stomach muscle|smooth muscle tissue of ventriculus|smooth muscle of ventriculus http://purl.obolibrary.org/obo/UBERON_0004222 UBERON:0004223 biolink:AnatomicalEntity vagina smooth muscle A portion of smooth muscle tissue that is part of a vagina [Automatically generated definition]. go-plus.json vagina involuntary muscle|non-striated muscle of vagina|vaginal smooth muscle|smooth muscle of vagina|smooth muscle tissue of vagina|vagina non-striated muscle|vagina smooth muscle tissue|vagina smooth muscle|involuntary muscle of vagina http://purl.obolibrary.org/obo/UBERON_0004223 RO:0002082 biolink:OntologyClass Relation between occurrents, shares start and end boundaries. RO:0002082 go-plus.json is_equal_to|coincides_with http://purl.obolibrary.org/obo/RO_0002082 UBERON:0004208 biolink:AnatomicalEntity nephrogenic mesenchyme Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron go-plus.json mesenchyme of nephron|nephron mesenchyme http://purl.obolibrary.org/obo/UBERON_0004208 UBERON:0004209 biolink:AnatomicalEntity renal vesicle The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. go-plus.json stage I nephron http://purl.obolibrary.org/obo/UBERON_0004209 RO:0002088 biolink:OntologyClass during which starts RO:0002088 go-plus.json http://purl.obolibrary.org/obo/RO_0002088 RO:0002084 biolink:OntologyClass during which ends RO:0002084 go-plus.json http://purl.obolibrary.org/obo/RO_0002084 RO:0002085 biolink:OntologyClass encompasses RO:0002085 go-plus.json http://purl.obolibrary.org/obo/RO_0002085 RO:0002086 biolink:OntologyClass ends after RO:0002086 go-plus.json http://purl.obolibrary.org/obo/RO_0002086 RO:0002087 biolink:OntologyClass immediately_preceded_by X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) RO:0002087 go-plus.json is directly preceded by|is immediately preceded by|starts_at_end_of|directly preceded by http://purl.obolibrary.org/obo/RO_0002087 CHEBI:33443 biolink:ChemicalSubstance halogen oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33443 CHEBI:33447 biolink:ChemicalSubstance phospho sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_33447 UBERON:0004217 biolink:AnatomicalEntity upper arm nerve A nerve that is part of a forelimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004217 UBERON:0004218 biolink:AnatomicalEntity lower leg nerve A nerve that is part of a lower leg [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004218 UBERON:0004215 biolink:AnatomicalEntity back nerve A nerve that is part of a back [Automatically generated definition]. go-plus.json nerve of back http://purl.obolibrary.org/obo/UBERON_0004215 UBERON:0004216 biolink:AnatomicalEntity lower arm nerve A nerve that is part of a lower arm [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004216 UBERON:0004214 biolink:AnatomicalEntity upper leg nerve A nerve that is part of a hindlimb stylopod [Automatically generated definition]. go-plus.json hindlimb stylopod nerve|thigh RELATED|lower extremity stylopod nerve|hind limb stylopod nerve http://purl.obolibrary.org/obo/UBERON_0004214 UBERON:0004211 biolink:AnatomicalEntity nephron epithelium The nephron epithelium is a tissue that covers the surface of a nephron go-plus.json nephron epithelial tissue|epithelium of nephron|epithelial tissue of nephron http://purl.obolibrary.org/obo/UBERON_0004211 UBERON:0004212 biolink:AnatomicalEntity glomerular capillary the small branching blood vessels in the kidney glomerulus that receives blood from the kidney afferent arterioles; these capillaries are under high pressure for filtering within the glomerulus go-plus.json capillary vessel of renal glomerulus|renal glomerulus blood capillary|renal glomerulus capillary vessel|glomerular capillaries|glomerular capillary system|capillary of renal glomerulus|blood capillary of renal glomerulus|renal glomerulus capillary http://purl.obolibrary.org/obo/UBERON_0004212 CHEBI:33415 biolink:ChemicalSubstance elemental carbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33415 CHEBI:33419 biolink:ChemicalSubstance monoatomic carbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33419 CHEBI:33410 biolink:ChemicalSubstance arsonite(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33410 CHEBI:33412 biolink:ChemicalSubstance diatomic sulfur go-plus.json http://purl.obolibrary.org/obo/CHEBI_33412 UBERON:0004206 biolink:AnatomicalEntity long descending thin limb bend The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment go-plus.json http://purl.obolibrary.org/obo/UBERON_0004206 UBERON:0004207 biolink:AnatomicalEntity prebend segment of loop of Henle The prebend segment is a part of the descending thin limb that lies before the bend and exhibits robust sodium chloride reabsorption go-plus.json prebend segment http://purl.obolibrary.org/obo/UBERON_0004207 UBERON:0004204 biolink:AnatomicalEntity outer medullary collecting duct The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla go-plus.json kidney outer medulla collecting duct|outer renal medulla collecting duct http://purl.obolibrary.org/obo/UBERON_0004204 UBERON:0004205 biolink:AnatomicalEntity inner medullary collecting duct The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla go-plus.json inner renal medulla collecting duct|kidney inner medulla collecting duct|papillary collecting duct http://purl.obolibrary.org/obo/UBERON_0004205 UBERON:0004202 biolink:AnatomicalEntity kidney outer medulla outer stripe The outer stripe is the region of the kidney that lies distal to the line of termination of the straight renal tubules go-plus.json outer medulla outer stripe|outer stripe of outer medulla|stria externa medullae renalis|outer stripe|outer stripe of renal medulla|outer stripe of medulla of kidney http://purl.obolibrary.org/obo/UBERON_0004202 UBERON:0004203 biolink:AnatomicalEntity cortical collecting duct The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex go-plus.json renal cortex collecting duct|kidney cortex collecting duct http://purl.obolibrary.org/obo/UBERON_0004203 UBERON:0004200 biolink:AnatomicalEntity kidney pyramid Kidney pyramids are the conical arrangements of tubules that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. go-plus.json renal pyramid|Malpighian pyramid|Malphigian pyramid|pyramid of Malphigi|Malpighian pyramid|pyramides renales|pyramid of Malpighi|medullary pyramid|renal medullary region|pyramis renalis|pyramid http://purl.obolibrary.org/obo/UBERON_0004200 UBERON:0004201 biolink:AnatomicalEntity kidney outer medulla inner stripe The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thick and thin portions of nephron tubules go-plus.json inner stripe of renal medulla|inner stripe of medulla of kidney|inner stripe|inner stripe of outer medulla|stria interna medullae renalis|outer medulla inner stripe http://purl.obolibrary.org/obo/UBERON_0004201 CHEBI:33426 biolink:ChemicalSubstance chlorine oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33426 CHEBI:33429 biolink:ChemicalSubstance monoatomic monoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33429 chebi_ph7_3 NCBITaxon:6072 biolink:OrganismalEntity Eumetazoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6072 NCBITaxon:6073 biolink:OrganismalEntity Cnidaria go-plus.json Coelenterata|cnidarians|cnidarians|coelenterates http://purl.obolibrary.org/obo/NCBITaxon_6073 CHEBI:33420 biolink:ChemicalSubstance diatomic carbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33420 CHEBI:33423 biolink:ChemicalSubstance monoatomic hexacation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33423 chebi_ph7_3 CHEBI:33424 biolink:ChemicalSubstance sulfur oxoacid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33424 CHEBI:33425 biolink:ChemicalSubstance halogen oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33425 RO:0002170 biolink:OntologyClass Binary relationship: x connected_to y if and only if there exists some z such that z connects x and y in a ternary connected_to(x,y,z) relationship. RO:0002170 go-plus.json http://purl.obolibrary.org/obo/RO_0002170 GO:0030138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030138 GO:0030139 biolink:CellularComponent endocytic vesicle A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting. NIF_Subcellular:sao1362520468 go-plus.json endocytotic transport vesicle|endocytotic vesicle http://purl.obolibrary.org/obo/GO_0030139 GO:0030136 biolink:CellularComponent clathrin-coated vesicle A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. NIF_Subcellular:sao148845161 go-plus.json http://purl.obolibrary.org/obo/GO_0030136 GO:0030137 biolink:CellularComponent COPI-coated vesicle A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport. go-plus.json coatomer http://purl.obolibrary.org/obo/GO_0030137 GO:0044786 biolink:BiologicalProcess cell cycle DNA replication The DNA-dependent DNA replication that takes place as part of the cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0044786 RO:0002176 biolink:OntologyClass Binary relationship: z connects x if and only if there exists some y such that z connects x and y in a ternary connected_to(x,y,z) relationship. RO:0002176 go-plus.json http://purl.obolibrary.org/obo/RO_0002176 GO:0005178 biolink:MolecularActivity integrin binding Binding to an integrin. go-plus.json integrin ligand http://purl.obolibrary.org/obo/GO_0005178 goslim_chembl GO:0005179 biolink:MolecularActivity hormone activity The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process. go-plus.json lipopeptide hormone|peptide hormone|glycopeptide hormone|cAMP generating peptide activity http://purl.obolibrary.org/obo/GO_0005179 goslim_chembl GO:0044787 biolink:BiologicalProcess bacterial-type DNA replication The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome. go-plus.json bacterial-type cell cycle DNA replication http://purl.obolibrary.org/obo/GO_0044787 CHEBI:140675 biolink:ChemicalSubstance 3-hydroxyacyl derivative of bacterial toxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140675 chebi_ph7_3 RO:0002177 biolink:OntologyClass RO:0002177 go-plus.json http://purl.obolibrary.org/obo/RO_0002177 RO:0002178 biolink:OntologyClass relation between an artery and the structure is supplies with blood. RO:0002178 go-plus.json arterial supply of http://purl.obolibrary.org/obo/RO_0002178 GO:0044784 biolink:BiologicalProcess metaphase/anaphase transition of cell cycle The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0044784 GO:0005176 biolink:MolecularActivity ErbB-2 class receptor binding Binding to a protein-tyrosine kinase receptor Neu/ErbB-2/HER2. go-plus.json Neu receptor ligand|HER2 receptor ligand|HER2 receptor binding|Neu receptor binding|ErbB-2 class receptor ligand http://purl.obolibrary.org/obo/GO_0005176 RO:0002179 biolink:OntologyClass RO:0002179 go-plus.json drains from|drains blood from http://purl.obolibrary.org/obo/RO_0002179 GO:0044785 biolink:BiologicalProcess metaphase/anaphase transition of meiotic cell cycle The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis. go-plus.json meiotic metaphase/anaphase transition http://purl.obolibrary.org/obo/GO_0044785 GO:0005177 biolink:MolecularActivity obsolete neuroligin OBSOLETE. A class of ligands for neurexins. go-plus.json neuroligin http://purl.obolibrary.org/obo/GO_0005177 GO:0044782 biolink:BiologicalProcess cilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. go-plus.json microtubule-based flagellum organization http://purl.obolibrary.org/obo/GO_0044782 goslim_drosophila GO:0005174 biolink:MolecularActivity CD40 receptor binding Binding to CD40, a receptor found on the surface of all B-lymphocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0005174 GO:0005175 biolink:MolecularActivity CD27 receptor binding Binding to a CD27, a receptor found on the surface of T cells and some B cells and NK cells. go-plus.json http://purl.obolibrary.org/obo/GO_0005175 GO:0044783 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044783 PATO:0002309 biolink:OntologyClass fiber shaped A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter. go-plus.json http://purl.obolibrary.org/obo/PATO_0002309 GO:0044780 biolink:BiologicalProcess bacterial-type flagellum assembly The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. go-plus.json bacterial flagellum assembly http://purl.obolibrary.org/obo/GO_0044780 GO:0005172 biolink:MolecularActivity vascular endothelial growth factor receptor binding Binding to a vascular endothelial growth factor receptor. go-plus.json vascular endothelial growth factor|VEGF receptor binding|VEGFR binding|vascular endothelial growth factor receptor ligand http://purl.obolibrary.org/obo/GO_0005172 GO:0005173 biolink:MolecularActivity stem cell factor receptor binding Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor. go-plus.json SCF|stem cell factor|stem cell factor receptor ligand|KIT binding|SCFR binding http://purl.obolibrary.org/obo/GO_0005173 GO:0044781 biolink:BiologicalProcess bacterial-type flagellum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. go-plus.json http://purl.obolibrary.org/obo/GO_0044781 GO:0005181 biolink:MolecularActivity obsolete glycopeptide hormone OBSOLETE. (Was not defined before being made obsolete). go-plus.json glycopeptide hormone http://purl.obolibrary.org/obo/GO_0005181 GO:0005182 biolink:MolecularActivity obsolete lipopeptide hormone OBSOLETE. (Was not defined before being made obsolete). go-plus.json lipopeptide hormone http://purl.obolibrary.org/obo/GO_0005182 GO:0005180 biolink:MolecularActivity obsolete peptide hormone OBSOLETE. (Was not defined before being made obsolete). go-plus.json peptide hormone http://purl.obolibrary.org/obo/GO_0005180 CHEBI:140678 biolink:ChemicalSubstance 4,4-dihydroxy-all-trans-beta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_140678 chebi_ph7_3 GO:0044788 biolink:BiologicalProcess modulation by host of viral process A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected. go-plus.json http://purl.obolibrary.org/obo/GO_0044788 CHEBI:140676 biolink:ChemicalSubstance 4',4'-dihydroxyechinenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_140676 chebi_ph7_3 GO:0044789 biolink:BiologicalProcess modulation by host of viral release from host cell A process in which a host organism modulates the frequency, rate or extent of the release of a virus with which it is infected, from its cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044789 CHEBI:140677 biolink:ChemicalSubstance 4-hydroxy-all-trans-beta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_140677 chebi_ph7_3 GO:0030134 biolink:CellularComponent COPII-coated ER to Golgi transport vesicle A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport). go-plus.json COPII-associated vesicle|COPII-associated ER to Golgi transport vesicle|endoplasmic reticulum-Golgi transport vesicle|ER to Golgi constitutive secretory pathway transport vesicle|ER-Golgi transport vesicle|COPII-coated vesicle|COPII vesicle|ER to Golgi transport vesicle|endoplasmic reticulum to Golgi transport vesicle http://purl.obolibrary.org/obo/GO_0030134 GO:0030135 biolink:CellularComponent coated vesicle Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins. NIF_Subcellular:sao1985096626 go-plus.json http://purl.obolibrary.org/obo/GO_0030135 goslim_drosophila GO:0030132 biolink:CellularComponent clathrin coat of coated pit The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex. go-plus.json http://purl.obolibrary.org/obo/GO_0030132 GO:0030133 biolink:CellularComponent transport vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. NIF_Subcellular:sao885490876 go-plus.json Golgi-vacuole transport vesicle|Golgi to vacuole transport vesicle|constitutive secretory pathway transport vesicle|secretory vesicle http://purl.obolibrary.org/obo/GO_0030133 GO:0030130 biolink:CellularComponent clathrin coat of trans-Golgi network vesicle A clathrin coat found on a vesicle of the trans-Golgi network. go-plus.json clathrin coat of TGN vesicle http://purl.obolibrary.org/obo/GO_0030130 GO:0030131 biolink:CellularComponent clathrin adaptor complex A membrane coat adaptor complex that links clathrin to a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0030131 GO:0044790 biolink:BiologicalProcess negative regulation by host of viral release from host cell A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044790 GO:0030129 biolink:CellularComponent clathrin coat of synaptic vesicle A clathrin coat found on a synaptic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030129 RO:0002160 biolink:OntologyClass only in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. RO:0002160 go-plus.json never_outside_taxon|specific_to_taxon|specific_to http://purl.obolibrary.org/obo/RO_0002160 GO:0030127 biolink:CellularComponent COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state. go-plus.json http://purl.obolibrary.org/obo/GO_0030127 GO:0030128 biolink:CellularComponent clathrin coat of endocytic vesicle A clathrin coat found on an endocytic vesicle. go-plus.json clathrin coat of endocytotic vesicle http://purl.obolibrary.org/obo/GO_0030128 GO:0030125 biolink:CellularComponent clathrin vesicle coat A clathrin coat found on a vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0030125 GO:0030126 biolink:CellularComponent COPI vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state. go-plus.json coatomer http://purl.obolibrary.org/obo/GO_0030126 CHEBI:140663 biolink:ChemicalSubstance N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140663 chebi_ph7_3 GO:0005189 biolink:MolecularActivity obsolete milk protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json milk protein http://purl.obolibrary.org/obo/GO_0005189 GO:0044797 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044797 CHEBI:140664 biolink:ChemicalSubstance S-(2-sulfodisulfanyl)-L-cysteine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140664 chebi_ph7_3 GO:0044798 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044798 GO:0044795 biolink:BiologicalProcess trans-Golgi network to recycling endosome transport The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0044795 GO:0005187 biolink:MolecularActivity obsolete storage protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json storage protein http://purl.obolibrary.org/obo/GO_0005187 CHEBI:140662 biolink:ChemicalSubstance 2,4-diacetylphloroglucinol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140662 chebi_ph7_3 GO:0044796 biolink:CellularComponent DNA polymerase processivity factor complex A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0044796 GO:0005188 biolink:MolecularActivity obsolete larval serum protein (sensu Insecta) OBSOLETE. (Was not defined before being made obsolete). go-plus.json arylphorin|larval serum protein (sensu Insecta) http://purl.obolibrary.org/obo/GO_0005188 GO:0044793 biolink:BiologicalProcess negative regulation by host of viral process A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected. go-plus.json http://purl.obolibrary.org/obo/GO_0044793 RO:0002161 biolink:OntologyClass never_in_taxon x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL. go-plus.json http://purl.obolibrary.org/obo/RO_0002161 GO:0005185 biolink:MolecularActivity neurohypophyseal hormone activity The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin. go-plus.json neurohypophysial hormone activity http://purl.obolibrary.org/obo/GO_0005185 GO:0044794 biolink:BiologicalProcess positive regulation by host of viral process A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected. go-plus.json http://purl.obolibrary.org/obo/GO_0044794 GO:0005186 biolink:MolecularActivity pheromone activity The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant. go-plus.json http://purl.obolibrary.org/obo/GO_0005186 RO:0002162 biolink:OntologyClass in taxon x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. RO:0002162 go-plus.json http://purl.obolibrary.org/obo/RO_0002162 CHEBI:140660 biolink:ChemicalSubstance a 2-acyl-sn-glycero-3-phospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140660 chebi_ph7_3 GO:0005183 biolink:MolecularActivity gonadotropin hormone-releasing hormone activity The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary. go-plus.json LH/FSH-RF|GnRH activity|luteinizing hormone-releasing factor activity|gonadotrophin hormone-releasing hormone activity|luteinizing hormone/follicle-stimulating hormone releasing factor activity|luteinizing hormone-releasing hormone activity|LHRH activity http://purl.obolibrary.org/obo/GO_0005183 GO:0044791 biolink:BiologicalProcess positive regulation by host of viral release from host cell A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044791 RO:0002163 biolink:OntologyClass spatially disjoint from A is spatially_disjoint_from B if and only if they have no parts in common RO:0002163 go-plus.json http://purl.obolibrary.org/obo/RO_0002163 GO:0005184 biolink:MolecularActivity neuropeptide hormone activity The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones. Wikipedia:Neurohormone go-plus.json neurohormone http://purl.obolibrary.org/obo/GO_0005184 goslim_chembl PATO:0002318 biolink:OntologyClass superelliptic A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt go-plus.json Lamé curve http://purl.obolibrary.org/obo/PATO_0002318 GO:0044792 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044792 CHEBI:57396 biolink:ChemicalSubstance vinylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57396 chebi_ph7_3 GO:0005192 biolink:MolecularActivity obsolete urinary protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json urinary protein http://purl.obolibrary.org/obo/GO_0005192 CHEBI:57397 biolink:ChemicalSubstance prostaglandin E1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57397 chebi_ph7_3 GO:0005193 biolink:MolecularActivity obsolete major urinary protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json major urinary protein http://purl.obolibrary.org/obo/GO_0005193 GO:0005190 biolink:MolecularActivity obsolete seminal fluid protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json seminal fluid protein http://purl.obolibrary.org/obo/GO_0005190 CHEBI:57394 biolink:ChemicalSubstance stearoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57394 chebi_ph7_3 CHEBI:57395 biolink:ChemicalSubstance thiophene-2-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57395 chebi_ph7_3 GO:0005191 biolink:MolecularActivity obsolete acidic epididymal glycoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json acidic epididymal glycoprotein http://purl.obolibrary.org/obo/GO_0005191 CHEBI:57392 biolink:ChemicalSubstance propionyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57392 chebi_ph7_3 OBO:go#syngo_official_label biolink:OntologyClass label approved by the SynGO project go-plus.json http://purl.obolibrary.org/obo/go#syngo_official_label RO:0002158 biolink:OntologyClass RO:0002158 go-plus.json http://purl.obolibrary.org/obo/RO_0002158 CHEBI:57393 biolink:ChemicalSubstance sinapoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57393 chebi_ph7_3 RO:0002159 biolink:OntologyClass RO:0002159 go-plus.json http://purl.obolibrary.org/obo/RO_0002159 GO:0044799 biolink:CellularComponent NarGHI complex A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit. go-plus.json nitrate reductase A|cytoplasmic membrane-bound quinol-nitrate oxidoreductase http://purl.obolibrary.org/obo/GO_0044799 CHEBI:57390 biolink:ChemicalSubstance phenylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57390 chebi_ph7_3 CHEBI:57391 biolink:ChemicalSubstance phytanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57391 chebi_ph7_3 GO:0030123 biolink:CellularComponent AP-3 adaptor complex A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B). go-plus.json http://purl.obolibrary.org/obo/GO_0030123 GO:0030124 biolink:CellularComponent AP-4 adaptor complex An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo. go-plus.json http://purl.obolibrary.org/obo/GO_0030124 GO:0030121 biolink:CellularComponent AP-1 adaptor complex A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). go-plus.json AP-1 related adapter complex|HA1|HA1 clathrin adaptor http://purl.obolibrary.org/obo/GO_0030121 GO:0030122 biolink:CellularComponent AP-2 adaptor complex A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). go-plus.json HA2|HA2 clathrin adaptor http://purl.obolibrary.org/obo/GO_0030122 GO:0030120 biolink:CellularComponent vesicle coat A membrane coat found on a coated vesicle. NIF_Subcellular:sao1177708494 go-plus.json http://purl.obolibrary.org/obo/GO_0030120 CHEBI:57398 biolink:ChemicalSubstance prostaglandin A1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57398 chebi_ph7_3 CHEBI:57399 biolink:ChemicalSubstance prostaglandin C1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57399 chebi_ph7_3 GO:0030118 biolink:CellularComponent clathrin coat A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes. Wikipedia:Clathrin|NIF_Subcellular:sao879919129 go-plus.json clathrin cage http://purl.obolibrary.org/obo/GO_0030118 GO:0030119 biolink:CellularComponent AP-type membrane coat adaptor complex Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa). go-plus.json clathrin adaptor http://purl.obolibrary.org/obo/GO_0030119 goslim_pir GO:0030116 biolink:MolecularActivity glial cell-derived neurotrophic factor receptor binding A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors. go-plus.json glial cell line-derived neurotrophic factor receptor ligand|glial cell line-derived neurotrophic factor receptor binding http://purl.obolibrary.org/obo/GO_0030116 GO:0030117 biolink:CellularComponent membrane coat Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules. go-plus.json http://purl.obolibrary.org/obo/GO_0030117 GO:0005158 biolink:MolecularActivity insulin receptor binding Binding to an insulin receptor. go-plus.json insulin receptor ligand http://purl.obolibrary.org/obo/GO_0005158 GO:0030114 biolink:CellularComponent slime layer A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids. Wikipedia:Slime_layer go-plus.json http://purl.obolibrary.org/obo/GO_0030114 GO:0030115 biolink:CellularComponent S-layer A crystalline protein layer surrounding some bacteria. Wikipedia:S-layer go-plus.json http://purl.obolibrary.org/obo/GO_0030115 goslim_pir GO:0005159 biolink:MolecularActivity insulin-like growth factor receptor binding Binding to an insulin-like growth factor receptor. go-plus.json IGF receptor binding|insulin-like growth factor receptor ligand|insulin-like growth factor http://purl.obolibrary.org/obo/GO_0005159 CHEBI:140652 biolink:ChemicalSubstance (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140652 chebi_ph7_3 GO:0005156 biolink:MolecularActivity obsolete epidermal growth factor receptor inhibiting ligand activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json EGFR inhibiting ligand activity|epidermal growth factor receptor inhibiting ligand activity|EGF receptor inhibiting ligand activity http://purl.obolibrary.org/obo/GO_0005156 GO:0005157 biolink:MolecularActivity macrophage colony-stimulating factor receptor binding Binding to a macrophage colony-stimulating factor receptor. go-plus.json macrophage colony-stimulating factor receptor ligand|M-CSF receptor binding|macrophage colony stimulating factor receptor binding http://purl.obolibrary.org/obo/GO_0005157 CHEBI:140650 biolink:ChemicalSubstance 4-[(E)-2-isocyanoethenyl]phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_140650 chebi_ph7_3 GO:0005154 biolink:MolecularActivity epidermal growth factor receptor binding Binding to an epidermal growth factor receptor. go-plus.json transforming growth factor alpha|TGF-alpha receptor binding|EGF receptor binding|EGF receptor ligand|TGFalpha receptor binding|EGFR binding|transforming growth factor alpha receptor ligand|epidermal growth factor|EGF|transforming growth factor alpha receptor binding|epidermal growth factor receptor ligand http://purl.obolibrary.org/obo/GO_0005154 goslim_chembl GO:0005155 biolink:MolecularActivity obsolete epidermal growth factor receptor activating ligand activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json EGF receptor activating ligand activity|EGFR activating ligand activity|epidermal growth factor receptor activating ligand activity http://purl.obolibrary.org/obo/GO_0005155 RO:0002150 biolink:OntologyClass RO:0002150 go-plus.json http://purl.obolibrary.org/obo/RO_0002150 GO:0005152 biolink:MolecularActivity interleukin-1 receptor antagonist activity Blocks the binding of interleukin-1 to the interleukin-1 receptor complex. go-plus.json IL-1ra http://purl.obolibrary.org/obo/GO_0005152 GO:0005153 biolink:MolecularActivity interleukin-8 receptor binding Binding to an interleukin-8 receptor. go-plus.json IL-8|interleukin-8 receptor ligand http://purl.obolibrary.org/obo/GO_0005153 goslim_chembl GO:0005150 biolink:MolecularActivity interleukin-1, type I receptor binding Binding to a Type I interleukin-1 receptor. go-plus.json interleukin-1, type I receptor ligand|IL-1 type I http://purl.obolibrary.org/obo/GO_0005150 GO:0005151 biolink:MolecularActivity interleukin-1, type II receptor binding Binding to a Type II interleukin-1 receptor. go-plus.json interleukin-1, type II receptor ligand|IL-1 type II http://purl.obolibrary.org/obo/GO_0005151 CHEBI:57385 biolink:ChemicalSubstance myristoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57385 chebi_ph7_3 GO:0005160 biolink:MolecularActivity transforming growth factor beta receptor binding Binding to a transforming growth factor beta receptor. go-plus.json transforming growth factor beta receptor ligand|activin|TGFbeta receptor binding|inhibin|transforming growth factor beta|TGF-beta receptor binding|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta receptor anchoring activity|transforming growth factor beta ligand binding to type I receptor http://purl.obolibrary.org/obo/GO_0005160 CHEBI:57386 biolink:ChemicalSubstance octanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57386 chebi_ph7_3 CHEBI:57383 biolink:ChemicalSubstance linoleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57383 chebi_ph7_3 CHEBI:140658 biolink:ChemicalSubstance S-1,2-diacyl-sn-glyceryl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140658 chebi_ph7_3 CHEBI:57384 biolink:ChemicalSubstance malonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57384 chebi_ph7_3 CHEBI:57381 biolink:ChemicalSubstance itaconyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57381 chebi_ph7_3 CHEBI:140656 biolink:ChemicalSubstance N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140656 chebi_ph7_3 CHEBI:57382 biolink:ChemicalSubstance lactoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57382 chebi_ph7_3 CHEBI:140657 biolink:ChemicalSubstance N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140657 chebi_ph7_3 GO:0019799 biolink:MolecularActivity tubulin N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine. EC:2.3.1.108|RHEA:15277|MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN go-plus.json tubulin acetyltransferase activity|TAT activity|acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity|alpha-tubulin acetyltransferase activity|alpha-tubulin N-acetyltransferase activity|acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity|acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity|alpha-tubulin acetylase activity http://purl.obolibrary.org/obo/GO_0019799 CHEBI:140654 biolink:ChemicalSubstance 3-[(E)-2-isocyanovinyl]indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_140654 chebi_ph7_3 CHEBI:57380 biolink:ChemicalSubstance icosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57380 chebi_ph7_3 CHEBI:140655 biolink:ChemicalSubstance 16alpha-hydroxy-beta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140655 chebi_ph7_3 GO:0019797 biolink:MolecularActivity procollagen-proline 3-dioxygenase activity Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2. KEGG_REACTION:R03218|MetaCyc:PROCOLLAGEN-PROLINE-3-DIOXYGENASE-RXN|RHEA:22872|Reactome:R-HSA-1980233|EC:1.14.11.7 go-plus.json proline,2-oxoglutarate 3-dioxygenase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|procollagen-proline,2-oxoglutarate 3-dioxygenase activity|prolyl 3-hydroxylase activity|protocollagen proline 3-hydroxylase activity|prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity http://purl.obolibrary.org/obo/GO_0019797 GO:0030112 biolink:CellularComponent glycocalyx A carbohydrate rich layer at the outermost periphery of a cell. Wikipedia:Glycocalyx go-plus.json http://purl.obolibrary.org/obo/GO_0030112 goslim_pir GO:0030113 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030113 GO:0019798 biolink:MolecularActivity procollagen-proline dioxygenase activity Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2. go-plus.json http://purl.obolibrary.org/obo/GO_0019798 GO:0019795 biolink:BiologicalProcess obsolete nonprotein amino acid biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins. go-plus.json nonprotein amino acid biosynthesis|nonprotein amino acid biosynthetic process|nonprotein amino acid anabolism|nonprotein amino acid synthesis|nonprotein amino acid formation http://purl.obolibrary.org/obo/GO_0019795 GO:0030110 biolink:MolecularActivity HLA-C specific inhibitory MHC class I receptor activity Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0030110 GO:0030111 biolink:BiologicalProcess regulation of Wnt signaling pathway Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway. go-plus.json regulation of Wnt-activated signaling pathway|regulation of frizzled signalling pathway|regulation of frizzled signaling pathway|regulation of Wnt receptor signalling pathway|regulation of Wnt receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030111 GO:0019796 biolink:BiologicalProcess obsolete nonprotein amino acid catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins. go-plus.json nonprotein amino acid degradation|nonprotein amino acid breakdown|nonprotein amino acid catabolism|nonprotein amino acid catabolic process http://purl.obolibrary.org/obo/GO_0019796 CHEBI:57389 biolink:ChemicalSubstance pentanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57389 chebi_ph7_3 GO:0019793 biolink:MolecularActivity obsolete ISG15 carrier activity OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other. go-plus.json interferon-stimulated gene-15 carrier activity|ISG15 carrier activity http://purl.obolibrary.org/obo/GO_0019793 GO:0019794 biolink:BiologicalProcess obsolete nonprotein amino acid metabolic process OBSOLETE. The chemical reactions and pathways involving any amino acid not found, or rarely found, in peptide linkage in proteins. go-plus.json nonprotein amino acid metabolic process|nonprotein amino acid metabolism http://purl.obolibrary.org/obo/GO_0019794 CHEBI:57387 biolink:ChemicalSubstance oleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57387 chebi_ph7_3 GO:0019791 biolink:MolecularActivity obsolete FAT10 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json FAT10 hydrolase activity http://purl.obolibrary.org/obo/GO_0019791 CHEBI:57388 biolink:ChemicalSubstance oxalyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57388 chebi_ph7_3 GO:0019792 biolink:MolecularActivity obsolete APG12 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json APG12 hydrolase activity http://purl.obolibrary.org/obo/GO_0019792 GO:0030109 biolink:MolecularActivity HLA-B specific inhibitory MHC class I receptor activity Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0030109 GO:0030107 biolink:MolecularActivity HLA-A specific inhibitory MHC class I receptor activity Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0030107 GO:0030108 biolink:MolecularActivity HLA-A specific activating MHC class I receptor activity Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0030108 GO:0030105 biolink:BiologicalProcess obsolete anaphylaxis OBSOLETE. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances. go-plus.json anaphylaxis http://purl.obolibrary.org/obo/GO_0030105 GO:0030106 biolink:MolecularActivity obsolete MHC class I receptor activity OBSOLETE. A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells). go-plus.json major histocompatibility complex class I receptor|MHC class I receptor activity|class I major histocompatibility complex antigen http://purl.obolibrary.org/obo/GO_0030106 GO:0030103 biolink:BiologicalProcess vasopressin secretion The regulated release of vasopressin from secretory granules into the blood. go-plus.json http://purl.obolibrary.org/obo/GO_0030103 GO:0005169 biolink:MolecularActivity neurotrophin TRKB receptor binding Binding to a neurotrophin TRKB receptor. go-plus.json neurotrophin TRKB receptor ligand http://purl.obolibrary.org/obo/GO_0005169 GO:0030104 biolink:BiologicalProcess water homeostasis Any process involved in the maintenance of an internal steady state of water within an organism or cell. Wikipedia:Osmoregulation go-plus.json regulation of osmotic pressure|osmoregulation http://purl.obolibrary.org/obo/GO_0030104 GO:0005167 biolink:MolecularActivity neurotrophin TRK receptor binding Binding to a neurotrophin TRK receptor. go-plus.json neurotrophin TRK receptor ligand http://purl.obolibrary.org/obo/GO_0005167 CHEBI:140641 biolink:ChemicalSubstance rhizobitoxine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140641 chebi_ph7_3 CHEBI:140642 biolink:ChemicalSubstance dihydrorhizobitoxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140642 chebi_ph7_3 GO:0005168 biolink:MolecularActivity neurotrophin TRKA receptor binding Binding to a neurotrophin TRKA receptor. go-plus.json neurotrophin TRKA receptor ligand http://purl.obolibrary.org/obo/GO_0005168 GO:0005165 biolink:MolecularActivity neurotrophin receptor binding Binding to a neurotrophin receptor. go-plus.json neurotrophin receptor ligand|neurotrophin http://purl.obolibrary.org/obo/GO_0005165 GO:0005166 biolink:MolecularActivity neurotrophin p75 receptor binding Binding to a neurotrophin p75 receptor. go-plus.json neurotrophin p75 receptor ligand http://purl.obolibrary.org/obo/GO_0005166 CHEBI:140640 biolink:ChemicalSubstance dihydroferuloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140640 chebi_ph7_3 GO:0005163 biolink:MolecularActivity nerve growth factor receptor binding Binding to a nerve growth factor receptor. go-plus.json nerve growth factor receptor ligand|neurotrophin|NGF receptor binding http://purl.obolibrary.org/obo/GO_0005163 GO:0005164 biolink:MolecularActivity tumor necrosis factor receptor binding Binding to a tumor necrosis factor receptor. go-plus.json tumor necrosis factor|tumor necrosis factor receptor ligand|TNF receptor binding http://purl.obolibrary.org/obo/GO_0005164 goslim_chembl GO:0005161 biolink:MolecularActivity platelet-derived growth factor receptor binding Binding to a platelet-derived growth factor receptor. go-plus.json PDGF receptor binding|PDGFR binding|platelet-derived growth factor|PDGF|platelet-derived growth factor receptor ligand http://purl.obolibrary.org/obo/GO_0005161 GO:0005162 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005162 GO:0005170 biolink:MolecularActivity neurotrophin TRKC receptor binding Binding to a neurotrophin TRKC receptor. go-plus.json neurotrophin TRKC receptor ligand http://purl.obolibrary.org/obo/GO_0005170 CHEBI:57374 biolink:ChemicalSubstance cyclohexa-1,5-diene-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57374 chebi_ph7_3 GO:0005171 biolink:MolecularActivity hepatocyte growth factor receptor binding Binding to an hepatocyte growth factor receptor. go-plus.json HGF receptor binding|hepatocyte growth factor receptor ligand|hepatocyte growth factor http://purl.obolibrary.org/obo/GO_0005171 CHEBI:57375 biolink:ChemicalSubstance lauroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57375 chebi_ph7_3 CHEBI:57372 biolink:ChemicalSubstance caffeoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57372 chebi_ph7_3 CHEBI:140647 biolink:ChemicalSubstance (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140647 chebi_ph7_3 CHEBI:140648 biolink:ChemicalSubstance (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140648 chebi_ph7_3 CHEBI:57373 biolink:ChemicalSubstance choloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57373 chebi_ph7_3 CHEBI:57370 biolink:ChemicalSubstance biotinyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57370 chebi_ph7_3 CHEBI:140646 biolink:ChemicalSubstance poly(2,5-ethylene furandicarboxylate)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140646 chebi_ph7_3 CHEBI:57371 biolink:ChemicalSubstance butyryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57371 chebi_ph7_3 GO:0030101 biolink:BiologicalProcess natural killer cell activation The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json NK cell activation http://purl.obolibrary.org/obo/GO_0030101 GO:0030102 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030102 GO:0030100 biolink:BiologicalProcess regulation of endocytosis Any process that modulates the frequency, rate or extent of endocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0030100 CHEBI:57378 biolink:ChemicalSubstance glutaryl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57378 chebi_ph7_3 CHEBI:57379 biolink:ChemicalSubstance palmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57379 chebi_ph7_3 CHEBI:57376 biolink:ChemicalSubstance formyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57376 chebi_ph7_3 CHEBI:57377 biolink:ChemicalSubstance cis-geranoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57377 chebi_ph7_3 GO:0005138 biolink:MolecularActivity interleukin-6 receptor binding Binding to an interleukin-6 receptor. go-plus.json IL-6|interleukin-6 receptor ligand http://purl.obolibrary.org/obo/GO_0005138 goslim_chembl GO:0005139 biolink:MolecularActivity interleukin-7 receptor binding Binding to an interleukin-7 receptor. go-plus.json IL-7|interleukin-7 receptor ligand http://purl.obolibrary.org/obo/GO_0005139 GO:0005136 biolink:MolecularActivity interleukin-4 receptor binding Binding to an interleukin-4 receptor. go-plus.json IL-4|interleukin-4 receptor ligand http://purl.obolibrary.org/obo/GO_0005136 GO:0005137 biolink:MolecularActivity interleukin-5 receptor binding Binding to an interleukin-5 receptor. go-plus.json IL-5|interleukin-5 receptor ligand http://purl.obolibrary.org/obo/GO_0005137 goslim_chembl GO:0005134 biolink:MolecularActivity interleukin-2 receptor binding Binding to an interleukin-2 receptor. go-plus.json IL-2|interleukin-2 receptor ligand http://purl.obolibrary.org/obo/GO_0005134 GO:0005135 biolink:MolecularActivity interleukin-3 receptor binding Binding to an interleukin-3 receptor. go-plus.json IL-3|interleukin-3 receptor ligand http://purl.obolibrary.org/obo/GO_0005135 RO:0002134 biolink:OntologyClass RO:0002134 go-plus.json http://purl.obolibrary.org/obo/RO_0002134 GO:0005132 biolink:MolecularActivity type I interferon receptor binding Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). go-plus.json interferon-alpha/beta receptor binding|interferon-alpha/beta|IFNAR2 binding|IFNAR1 binding|IFNAR binding|interferon-alpha/beta receptor ligand http://purl.obolibrary.org/obo/GO_0005132 GO:0005133 biolink:MolecularActivity interferon-gamma receptor binding Binding to an interferon-gamma receptor. go-plus.json interferon-gamma|interferon-gamma receptor ligand http://purl.obolibrary.org/obo/GO_0005133 GO:0005130 biolink:MolecularActivity granulocyte colony-stimulating factor receptor binding Binding to a granulocyte colony-stimulating factor receptor. go-plus.json G-CSF receptor ligand|granulocyte colony-stimulating factor|granulocyte colony stimulating factor receptor binding|GC-SF receptor ligand|granulocyte colony-stimulating factor receptor ligand http://purl.obolibrary.org/obo/GO_0005130 GO:0005131 biolink:MolecularActivity growth hormone receptor binding Binding to a growth hormone receptor. go-plus.json growth hormone receptor ligand|growth hormone http://purl.obolibrary.org/obo/GO_0005131 RO:0002131 biolink:OntologyClass overlaps A overlaps B if they share some part in common. RO:0002131 go-plus.json http://purl.obolibrary.org/obo/RO_0002131 CHEBI:57363 biolink:ChemicalSubstance gamma-linolenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57363 chebi_ph7_3 CHEBI:140638 biolink:ChemicalSubstance 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140638 chebi_ph7_3 CHEBI:57364 biolink:ChemicalSubstance 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57364 chebi_ph7_3 CHEBI:140639 biolink:ChemicalSubstance dihydro-4-coumaroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140639 chebi_ph7_3 CHEBI:140636 biolink:ChemicalSubstance 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140636 chebi_ph7_3 CHEBI:57361 biolink:ChemicalSubstance 6-hydroxycyclohex-1-ene-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57361 chebi_ph7_3 CHEBI:57362 biolink:ChemicalSubstance beta-alanyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57362 chebi_ph7_3 CHEBI:140637 biolink:ChemicalSubstance 7beta-hydroxy-3-oxochol-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140637 chebi_ph7_3 GO:0019779 biolink:MolecularActivity Atg8 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json APG8 activating enzyme activity|APG7 http://purl.obolibrary.org/obo/GO_0019779 CHEBI:140634 biolink:ChemicalSubstance 3-oxochol-4,6-dien-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140634 chebi_ph7_3 CHEBI:57360 biolink:ChemicalSubstance pimeloyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57360 chebi_ph7_3 CHEBI:140635 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140635 chebi_ph7_3 GO:0019777 biolink:MolecularActivity Atg12 transferase activity Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages. Reactome:R-HSA-5681999 go-plus.json APG12 ligase activity|APG12 conjugating enzyme activity|Atg12 ligase activity|Atg12 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0019777 CHEBI:140632 biolink:ChemicalSubstance 5-methylaminomethyl-S-(2E)-geranyl-thiouridine 5'-monophosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140632 chebi_ph7_3 CHEBI:140633 biolink:ChemicalSubstance 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140633 chebi_ph7_3 GO:0019778 biolink:MolecularActivity Atg12 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json APG12 activating enzyme activity http://purl.obolibrary.org/obo/GO_0019778 GO:0019775 biolink:MolecularActivity FAT10 transferase activity Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages. go-plus.json FAT10 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0019775 GO:0019776 biolink:MolecularActivity Atg8 ligase activity Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate. Reactome:R-HSA-5681981 go-plus.json Atg8 conjugating enzyme activity|APG8 ligase activity|APG8 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0019776 CHEBI:57369 biolink:ChemicalSubstance benzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57369 chebi_ph7_3 GO:0019773 biolink:CellularComponent proteasome core complex, alpha-subunit complex The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0019773 GO:0019774 biolink:CellularComponent proteasome core complex, beta-subunit complex The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0019774 GO:0019771 biolink:MolecularActivity high-affinity IgG receptor activity Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json high affinity Fc receptor activity|high affinity IgG receptor activity http://purl.obolibrary.org/obo/GO_0019771 CHEBI:57367 biolink:ChemicalSubstance acryloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57367 chebi_ph7_3 CHEBI:57368 biolink:ChemicalSubstance arachidonoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57368 chebi_ph7_3 GO:0019772 biolink:MolecularActivity low-affinity IgG receptor activity Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json low affinity IgG receptor activity|low affinity Fc receptor activity http://purl.obolibrary.org/obo/GO_0019772 CHEBI:57365 biolink:ChemicalSubstance 5-hydroxy-2-furoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57365 chebi_ph7_3 CHEBI:57366 biolink:ChemicalSubstance L-3-aminobutanoyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57366 chebi_ph7_3 GO:0019770 biolink:MolecularActivity IgG receptor activity Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0019770 GO:0019790 biolink:MolecularActivity obsolete ubiquitin-like hydrolase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ubiquitin-like hydrolase activity http://purl.obolibrary.org/obo/GO_0019790 GO:0005149 biolink:MolecularActivity interleukin-1 receptor binding Binding to an interleukin-1 receptor. go-plus.json IL-1|interleukin-1 receptor ligand http://purl.obolibrary.org/obo/GO_0005149 GO:0005147 biolink:MolecularActivity oncostatin-M receptor binding Binding to an oncostatin-M receptor. go-plus.json oncostatin-M|oncostatin-M receptor ligand http://purl.obolibrary.org/obo/GO_0005147 GO:0005148 biolink:MolecularActivity prolactin receptor binding Binding to a prolactin receptor. go-plus.json prolactin receptor ligand|prolactin http://purl.obolibrary.org/obo/GO_0005148 GO:0005145 biolink:MolecularActivity interleukin-14 receptor binding Binding to an interleukin-14 receptor. go-plus.json IL-14|interleukin-14 receptor ligand http://purl.obolibrary.org/obo/GO_0005145 GO:0005146 biolink:MolecularActivity leukemia inhibitory factor receptor binding Binding to an leukemia inhibitory factor receptor. go-plus.json leukemia inhibitory factor|leukemia inhibitory factor receptor ligand http://purl.obolibrary.org/obo/GO_0005146 CHEBI:140620 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140620 chebi_ph7_3 GO:0005143 biolink:MolecularActivity interleukin-12 receptor binding Binding to an interleukin-12 receptor. go-plus.json IL-12|interleukin-12 receptor ligand http://purl.obolibrary.org/obo/GO_0005143 GO:0005144 biolink:MolecularActivity interleukin-13 receptor binding Binding to an interleukin-13 receptor. go-plus.json IL-13|interleukin-13 receptor ligand http://purl.obolibrary.org/obo/GO_0005144 GO:0005141 biolink:MolecularActivity interleukin-10 receptor binding Binding to an interleukin-10 receptor. go-plus.json interleukin-10 receptor ligand|IL-10 http://purl.obolibrary.org/obo/GO_0005141 GO:0005142 biolink:MolecularActivity interleukin-11 receptor binding Binding to an interleukin-11 receptor. go-plus.json interleukin-11 receptor ligand|IL-11 http://purl.obolibrary.org/obo/GO_0005142 GO:0005140 biolink:MolecularActivity interleukin-9 receptor binding Binding to an interleukin-9 receptor. go-plus.json interleukin-9 receptor ligand|IL-9 http://purl.obolibrary.org/obo/GO_0005140 RO:0002120 biolink:OntologyClass RO:0002120 go-plus.json http://purl.obolibrary.org/obo/RO_0002120 CHEBI:140627 biolink:ChemicalSubstance RNA(n)-3'-uridine ribonucleotide polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140627 chebi_ph7_3 CHEBI:57352 biolink:ChemicalSubstance 4-aminobutanoyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57352 chebi_ph7_3 CHEBI:57353 biolink:ChemicalSubstance trans-4-carboxybut-2-enoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57353 chebi_ph7_3 CHEBI:140625 biolink:ChemicalSubstance 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140625 chebi_ph7_3 CHEBI:57350 biolink:ChemicalSubstance 3-oxopimeloyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57350 chebi_ph7_3 CHEBI:140626 biolink:ChemicalSubstance RNA(n)-3'-adenine ribonucleotide polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140626 chebi_ph7_3 CHEBI:57351 biolink:ChemicalSubstance 4,8,12-trimethyltridecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57351 chebi_ph7_3 CHEBI:140623 biolink:ChemicalSubstance Monosialyl-Gb5(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140623 chebi_ph7_3 CHEBI:140624 biolink:ChemicalSubstance Disialosyl Gb5(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140624 chebi_ph7_3 GO:0019788 biolink:MolecularActivity NEDD8 transferase activity Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages. Reactome:R-HSA-8951661|Reactome:R-HSA-8952618|Reactome:R-HSA-8951648|Reactome:R-HSA-8956025|Reactome:R-HSA-8952638|Reactome:R-HSA-8952044|Reactome:R-HSA-8951764 go-plus.json NEDD8 conjugating enzyme activity|Hub1 conjugating enzyme activity|RUB1 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0019788 GO:0019789 biolink:MolecularActivity SUMO transferase activity Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages. Reactome:R-HSA-4551724|Reactome:R-HSA-3900177|Reactome:R-HSA-4641342|Reactome:R-HSA-4755479|Reactome:R-HSA-3108209|Reactome:R-HSA-4090408|Reactome:R-HSA-5228521|Reactome:R-HSA-4551604|Reactome:R-HSA-2997706|Reactome:R-HSA-4551661|Reactome:R-HSA-5684052|Reactome:R-HSA-3927824|Reactome:R-HSA-4568914|Reactome:R-HSA-3900070|Reactome:R-HSA-4551648|Reactome:R-HSA-3232162|Reactome:R-HSA-4551679|Reactome:R-HSA-5228525|Reactome:R-HSA-4341070|Reactome:R-HSA-4755536|Reactome:R-HSA-2997723|Reactome:R-HSA-4570499|Reactome:R-HSA-3000449|Reactome:R-HSA-6790454|Reactome:R-HSA-4090284|Reactome:R-HSA-4755478|Reactome:R-HSA-3968362|Reactome:R-HSA-4717461|Reactome:R-HSA-4086083|Reactome:R-HSA-4551727|Reactome:R-HSA-2997709|Reactome:R-HSA-3000434|Reactome:R-HSA-4086036|Reactome:R-HSA-4656914|Reactome:R-HSA-4551738|Reactome:R-HSA-4655431|Reactome:R-HSA-4719436|Reactome:R-HSA-4570496|Reactome:R-HSA-3899291|Reactome:R-HSA-4570467|Reactome:R-HSA-4570554|Reactome:R-HSA-4085372|Reactome:R-HSA-4570489|Reactome:R-HSA-4551768|Reactome:R-HSA-4570528|Reactome:R-HSA-4719413|Reactome:R-HSA-4085318|Reactome:R-HSA-3234094|Reactome:R-HSA-4570485|Reactome:R-HSA-3234084|Reactome:R-HSA-3900047|Reactome:R-HSA-4719447|Reactome:R-HSA-4086088|Reactome:R-HSA-4551721|Reactome:R-HSA-4655440|Reactome:R-HSA-3968414|Reactome:R-HSA-4655355|Reactome:R-HSA-3108203|Reactome:R-HSA-4546387|Reactome:R-HSA-3000348|Reactome:R-HSA-4551616|Reactome:R-HSA-4090390|Reactome:R-HSA-4570493|Reactome:R-HSA-3234081|Reactome:R-HSA-4086059|Reactome:R-HSA-4615889|Reactome:R-HSA-4615910|Reactome:R-HSA-5682607|Reactome:R-HSA-4719423|Reactome:R-HSA-4615905|Reactome:R-HSA-3296126|Reactome:R-HSA-4085994|Reactome:R-HSA-4755526|Reactome:R-HSA-3927886|Reactome:R-HSA-4720432|Reactome:R-HSA-4085992|Reactome:R-HSA-3000399|Reactome:R-HSA-4085350|Reactome:R-HSA-3000433|Reactome:R-HSA-4568863|Reactome:R-HSA-4719448|Reactome:R-HSA-4570553|Reactome:R-HSA-4720446|Reactome:R-HSA-4755411|Reactome:R-HSA-5228523|Reactome:R-HSA-5228508|Reactome:R-HSA-4090281|Reactome:R-HSA-2997616|Reactome:R-HSA-2993769|Reactome:R-HSA-4568848|Reactome:R-HSA-4341073|Reactome:R-HSA-4616015|Reactome:R-HSA-4551655|Reactome:R-HSA-4641350|Reactome:R-HSA-6804485|Reactome:R-HSA-4546386|Reactome:R-HSA-4568846|Reactome:R-HSA-4090288|Reactome:R-HSA-4755494|Reactome:R-HSA-4615900|Reactome:R-HSA-4085296|Reactome:R-HSA-3000411|Reactome:R-HSA-4546385|Reactome:R-HSA-3782535|Reactome:R-HSA-6804468|Reactome:R-HSA-4341025|Reactome:R-HSA-4615839|Reactome:R-HSA-3108212|Reactome:R-HSA-4615933|Reactome:R-HSA-4615872|Reactome:R-HSA-4551683|Reactome:R-HSA-4341016|Reactome:R-HSA-4085347|Reactome:R-HSA-4655374|Reactome:R-HSA-3465545|Reactome:R-HSA-3247493|Reactome:R-HSA-8956365|Reactome:R-HSA-4341048|Reactome:R-HSA-4615873|Reactome:R-HSA-3927959|Reactome:R-HSA-4641345|Reactome:R-HSA-4641362|Reactome:R-HSA-4717521|Reactome:R-HSA-4615987|Reactome:R-HSA-4341072|Reactome:R-HSA-4085331|Reactome:R-HSA-2993780|Reactome:R-HSA-4719424|Reactome:R-HSA-3903017|Reactome:R-HSA-3000383|Reactome:R-HSA-3900194|Reactome:R-HSA-2993790|Reactome:R-HSA-4551649|Reactome:R-HSA-4570463 go-plus.json SUMO conjugating enzyme activity|SMT3 conjugating enzyme http://purl.obolibrary.org/obo/GO_0019789 GO:0019786 biolink:MolecularActivity Atg8-specific protease activity Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier. go-plus.json APG8-PE hydrolase|APG8-specific protease activity http://purl.obolibrary.org/obo/GO_0019786 GO:0019787 biolink:MolecularActivity ubiquitin-like protein transferase activity Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein. Reactome:R-HSA-688137|Reactome:R-HSA-5678490 go-plus.json small conjugating protein ligase activity|ubiquitin-like conjugating enzyme activity|E3|small conjugating protein transferase activity|ubiquitin-like-protein ligase activity|small protein conjugating enzyme activity|E2 http://purl.obolibrary.org/obo/GO_0019787 goslim_drosophila|goslim_pir GO:0019784 biolink:MolecularActivity NEDD8-specific protease activity Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates. Reactome:R-HSA-8863723|Reactome:R-HSA-8956040|Reactome:R-HSA-5690808|Reactome:R-HSA-8956045 go-plus.json deneddylase activity http://purl.obolibrary.org/obo/GO_0019784 CHEBI:57358 biolink:ChemicalSubstance 5-hydroxythiophene-2-carbonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57358 chebi_ph7_3 GO:0019785 biolink:MolecularActivity ISG15-specific protease activity Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates. Reactome:R-HSA-5653786|Reactome:R-HSA-1678841 go-plus.json http://purl.obolibrary.org/obo/GO_0019785 CHEBI:57359 biolink:ChemicalSubstance 2,3-didehydropimeloyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57359 chebi_ph7_3 GO:0019782 biolink:MolecularActivity ISG15 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json UBE1L http://purl.obolibrary.org/obo/GO_0019782 CHEBI:57356 biolink:ChemicalSubstance 4-hydroxybenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57356 chebi_ph7_3 GO:0019783 biolink:MolecularActivity ubiquitin-like protein-specific protease activity Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated. go-plus.json ubiquitin-specific protease activity involved in positive regulation of ERAD pathway|ubiquitin-like specific protease activity|ubiquitin-like-protein-specific protease activity|small conjugating protein-specific protease activity|ubiquitin-specific protease activity involved in negative regulation of ERAD pathway http://purl.obolibrary.org/obo/GO_0019783 CHEBI:57357 biolink:ChemicalSubstance 5-hydroxypentanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57357 chebi_ph7_3 CHEBI:140629 biolink:ChemicalSubstance dialurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140629 chebi_ph7_3 CHEBI:57354 biolink:ChemicalSubstance 4-chlorobenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57354 chebi_ph7_3 GO:0019780 biolink:MolecularActivity FAT10 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json http://purl.obolibrary.org/obo/GO_0019780 GO:0019781 biolink:MolecularActivity NEDD8 activating enzyme activity Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade. go-plus.json RUB1 activating enzyme activity http://purl.obolibrary.org/obo/GO_0019781 CHEBI:57355 biolink:ChemicalSubstance 4-coumaroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57355 chebi_ph7_3 GO:0005118 biolink:MolecularActivity sevenless binding Binding to a sevenless (sev) protein, a receptor tyrosine kinase. go-plus.json sev binding|sev ligand|sevenless ligand http://purl.obolibrary.org/obo/GO_0005118 GO:0005119 biolink:MolecularActivity smoothened binding Binding to a smoothened (smo) protein, which interacts with patched to transmit hedgehog signals. go-plus.json smo ligand|smoothened ligand|smo binding http://purl.obolibrary.org/obo/GO_0005119 GO:0005116 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005116 GO:0005117 biolink:MolecularActivity wishful thinking binding Binding to wishful thinking (Wit), a type II bone morphogenic protein receptor. go-plus.json Wit binding|wishful thinking ligand|SE20 receptor binding|Wit ligand http://purl.obolibrary.org/obo/GO_0005117 GO:0005114 biolink:MolecularActivity type II transforming growth factor beta receptor binding Binding to a type II transforming growth factor beta receptor. go-plus.json type II TGF-beta binding|punt ligand|transforming growth factor beta ligand binding to type II receptor|punt binding|TGF-beta type II binding|transforming growth factor beta receptor type II binding http://purl.obolibrary.org/obo/GO_0005114 GO:0005115 biolink:MolecularActivity receptor tyrosine kinase-like orphan receptor binding Binding to a receptor tyrosine kinase-like orphan receptor (Ror). go-plus.json receptor tyrosine kinase-like orphan receptor ligand|Ror ligand|Ror binding http://purl.obolibrary.org/obo/GO_0005115 GO:0005112 biolink:MolecularActivity Notch binding Binding to a Notch (N) protein, a surface receptor. go-plus.json Notch receptor binding|N ligand|Notch ligand|N binding http://purl.obolibrary.org/obo/GO_0005112 GO:0005113 biolink:MolecularActivity patched binding Binding to a patched (ptc) protein, a receptor for hedgehog proteins. go-plus.json ptc binding|ptc ligand|patched ligand http://purl.obolibrary.org/obo/GO_0005113 GO:0005110 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005110 GO:0005111 biolink:MolecularActivity type 2 fibroblast growth factor receptor binding Binding to a type 2 fibroblast growth factor receptor (FGFR2). go-plus.json heartless binding|heartless ligand|type 2 fibroblast growth factor receptor ligand|FGFR2 ligand|FGFR2 binding http://purl.obolibrary.org/obo/GO_0005111 CHEBI:57341 biolink:ChemicalSubstance 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57341 chebi_ph7_3 CHEBI:140616 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140616 chebi_ph7_3 CHEBI:140617 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140617 chebi_ph7_3 CHEBI:57342 biolink:ChemicalSubstance 3-hydroxybenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57342 chebi_ph7_3 CHEBI:140614 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140614 chebi_ph7_3 GO:0019759 biolink:BiologicalProcess glycosinolate catabolic process The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae. go-plus.json glycosinolate catabolism|glycosinolate degradation|glycosinolate breakdown http://purl.obolibrary.org/obo/GO_0019759 CHEBI:57340 biolink:ChemicalSubstance 3-hydroxy-2-methylpropanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57340 chebi_ph7_3 CHEBI:140615 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140615 chebi_ph7_3 CHEBI:139612 biolink:ChemicalSubstance O(3)-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139612 chebi_ph7_3 GO:0019757 biolink:BiologicalProcess glycosinolate metabolic process The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae. go-plus.json glycosinolate metabolism http://purl.obolibrary.org/obo/GO_0019757 RO:0002103 biolink:OntologyClass RO:0002103 go-plus.json http://purl.obolibrary.org/obo/RO_0002103 CHEBI:140613 biolink:ChemicalSubstance L,L-homocystine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140613 chebi_ph7_3 GO:0019758 biolink:BiologicalProcess glycosinolate biosynthetic process The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae. go-plus.json glycosinolate anabolism|glycosinolate synthesis|glycosinolate biosynthesis|glycosinolate formation http://purl.obolibrary.org/obo/GO_0019758 RO:0002104 biolink:OntologyClass RO:0002104 go-plus.json http://purl.obolibrary.org/obo/RO_0002104 CHEBI:139613 biolink:ChemicalSubstance calcidiol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139613 GO:0019755 biolink:BiologicalProcess one-carbon compound transport The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json one carbon compound transport http://purl.obolibrary.org/obo/GO_0019755 CHEBI:140610 biolink:ChemicalSubstance 4'-hydroxyechinenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_140610 chebi_ph7_3 GO:0019756 biolink:BiologicalProcess cyanogenic glycoside biosynthetic process The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits. go-plus.json cyanogenic glycoside biosynthesis|cyanogenic glycoside anabolism|cyanogenic glycoside synthesis|cyanogenic glycoside formation http://purl.obolibrary.org/obo/GO_0019756 GO:0019753 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019753 CHEBI:57349 biolink:ChemicalSubstance 3-oxopalmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57349 chebi_ph7_3 GO:0019754 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019754 CHEBI:139610 biolink:ChemicalSubstance calcidiol 25-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139610 GO:0019751 biolink:BiologicalProcess polyol metabolic process The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. go-plus.json polyhydric alcohol metabolic process|polyol metabolism http://purl.obolibrary.org/obo/GO_0019751 CHEBI:57347 biolink:ChemicalSubstance 3-oxo-fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57347 chebi_ph7_3 GO:0019752 biolink:BiologicalProcess carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). go-plus.json carboxylic acid metabolism http://purl.obolibrary.org/obo/GO_0019752 CHEBI:57348 biolink:ChemicalSubstance 3-oxoadipyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57348 chebi_ph7_3 CHEBI:139611 biolink:ChemicalSubstance O(3)-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139611 chebi_ph7_3 CHEBI:57345 biolink:ChemicalSubstance isovaleryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57345 chebi_ph7_3 GO:0019750 biolink:BiologicalProcess chloroplast localization Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants. go-plus.json chloroplast localisation http://purl.obolibrary.org/obo/GO_0019750 CHEBI:57346 biolink:ChemicalSubstance trans-3-methylglutaconyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57346 chebi_ph7_3 CHEBI:57343 biolink:ChemicalSubstance 3-hydroxypimeloyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57343 chebi_ph7_3 CHEBI:57344 biolink:ChemicalSubstance 3-methylbut-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57344 chebi_ph7_3 CHEBI:140619 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140619 chebi_ph7_3 GO:0005129 biolink:MolecularActivity granulocyte macrophage colony-stimulating factor receptor binding Binding to a granulocyte macrophage colony-stimulating factor receptor. go-plus.json granulocyte macrophage colony-stimulating factor receptor ligand|GMC-SF receptor ligand|GM-CSF receptor binding|granulocyte macrophage colony stimulating factor receptor binding|granulocyte macrophage colony-stimulating factor|GM-CSF receptor ligand http://purl.obolibrary.org/obo/GO_0005129 GO:0005127 biolink:MolecularActivity ciliary neurotrophic factor receptor binding Binding to a ciliary neurotrophic factor receptor. go-plus.json ciliary neurotrophic factor|ciliary neurotrophic factor receptor ligand http://purl.obolibrary.org/obo/GO_0005127 GO:0005128 biolink:MolecularActivity erythropoietin receptor binding Binding to an erythropoietin receptor. go-plus.json erythropoietin receptor ligand|erythropoietin http://purl.obolibrary.org/obo/GO_0005128 GO:0005125 biolink:MolecularActivity cytokine activity The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells. go-plus.json paracrine activity|autocrine activity http://purl.obolibrary.org/obo/GO_0005125 goslim_chembl GO:0005126 biolink:MolecularActivity cytokine receptor binding Binding to a cytokine receptor. go-plus.json hematopoietin/interferon-class (D200-domain) cytokine receptor ligand|hematopoietin/interferon-class (D200-domain) cytokine receptor binding http://purl.obolibrary.org/obo/GO_0005126 GO:0005123 biolink:MolecularActivity death receptor binding Binding to a member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD). go-plus.json death receptor interacting protein activity|EDAR binding|DR binding|KILLER binding|TNFR1 binding|death receptor ligand|TRAIL binding|NGFR binding|death receptor-associated factor activity|APO binding|FAS binding|death receptor adaptor protein activity http://purl.obolibrary.org/obo/GO_0005123 goslim_chembl GO:0005124 biolink:MolecularActivity scavenger receptor binding Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles. go-plus.json scavenger receptor ligand http://purl.obolibrary.org/obo/GO_0005124 RO:0002100 biolink:OntologyClass RO:0002100 go-plus.json http://purl.obolibrary.org/obo/RO_0002100 GO:0005121 biolink:MolecularActivity Toll binding Binding to a Toll protein, a transmembrane receptor. go-plus.json Toll receptor binding|Tl binding|Toll ligand http://purl.obolibrary.org/obo/GO_0005121 GO:0005122 biolink:MolecularActivity torso binding Binding to a torso (tor) protein, a receptor tyrosine kinase. go-plus.json torso ligand|tor binding|tor ligand http://purl.obolibrary.org/obo/GO_0005122 RO:0002102 biolink:OntologyClass RO:0002102 go-plus.json http://purl.obolibrary.org/obo/RO_0002102 GO:0005120 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005120 CHEBI:57330 biolink:ChemicalSubstance trans-dodec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57330 chebi_ph7_3 CHEBI:140605 biolink:ChemicalSubstance tetrahydrosulfopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140605 chebi_ph7_3 CHEBI:140606 biolink:ChemicalSubstance 5,10-methylenetetrahydrosulfopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140606 chebi_ph7_3 CHEBI:57331 biolink:ChemicalSubstance anthraniloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57331 chebi_ph7_3 CHEBI:140603 biolink:ChemicalSubstance 3-acetamido-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140603 CHEBI:140604 biolink:ChemicalSubstance heparan sulfate alpha-D-glucosaminide 6-sulfate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140604 chebi_ph7_3 GO:0019768 biolink:MolecularActivity high-affinity IgE receptor activity Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json high affinity Fc receptor activity|high affinity IgE receptor activity http://purl.obolibrary.org/obo/GO_0019768 CHEBI:140601 biolink:ChemicalSubstance fatty acid 4:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_140601 CHEBI:140602 biolink:ChemicalSubstance Arabidopsis thaliana metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_140602 GO:0019769 biolink:MolecularActivity low-affinity IgE receptor activity Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json low affinity Fc receptor activity|low affinity IgE receptor activity http://purl.obolibrary.org/obo/GO_0019769 GO:0019766 biolink:MolecularActivity IgA receptor activity Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0019766 GO:0019767 biolink:MolecularActivity IgE receptor activity Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0019767 CHEBI:140600 biolink:ChemicalSubstance alpha-D-xylose-(1->3)-alpha-D-xylose-(1->3)-beta-D-glucose-L-threonyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140600 chebi_ph7_3 GO:0019764 biolink:MolecularActivity obsolete high affinity Fc receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json high affinity Fc receptor activity http://purl.obolibrary.org/obo/GO_0019764 CHEBI:57338 biolink:ChemicalSubstance isobutyryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57338 chebi_ph7_3 GO:0019765 biolink:MolecularActivity obsolete low affinity Fc receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json low affinity Fc receptor activity http://purl.obolibrary.org/obo/GO_0019765 CHEBI:57339 biolink:ChemicalSubstance 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57339 chebi_ph7_3 GO:0019762 biolink:BiologicalProcess glucosinolate catabolic process The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. MetaCyc:PWY-5267 go-plus.json glucosinolate degradation|glucosinolate breakdown|glucosinolate catabolism http://purl.obolibrary.org/obo/GO_0019762 CHEBI:57336 biolink:ChemicalSubstance 2-methylbutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57336 chebi_ph7_3 GO:0019763 biolink:MolecularActivity immunoglobulin receptor activity Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json FC receptor activity http://purl.obolibrary.org/obo/GO_0019763 CHEBI:57337 biolink:ChemicalSubstance 2-methylcrotonoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57337 chebi_ph7_3 GO:0019760 biolink:BiologicalProcess glucosinolate metabolic process The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans. go-plus.json glucosinolate metabolism http://purl.obolibrary.org/obo/GO_0019760 CHEBI:57334 biolink:ChemicalSubstance 2-hydroxyphytanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57334 chebi_ph7_3 GO:0019761 biolink:BiologicalProcess glucosinolate biosynthetic process The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. go-plus.json glucosinolate biosynthesis|glucosinolate anabolism|glucosinolate synthesis|glucosinolate formation http://purl.obolibrary.org/obo/GO_0019761 CHEBI:57335 biolink:ChemicalSubstance 2-methylacetoacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57335 chebi_ph7_3 CHEBI:140607 biolink:ChemicalSubstance S-(ADP-D-ribosyl)-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140607 chebi_ph7_3 CHEBI:57332 biolink:ChemicalSubstance crotonoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57332 chebi_ph7_3 CHEBI:33384 biolink:ChemicalSubstance L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33384 chebi_ph7_3 CHEBI:57333 biolink:ChemicalSubstance 2-furoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57333 chebi_ph7_3 CHEBI:72960 biolink:ChemicalSubstance N-dodecanoylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72960 chebi_ph7_3 CHEBI:72961 biolink:ChemicalSubstance N-octadecanoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72961 chebi_ph7_3 CHEBI:72962 biolink:ChemicalSubstance N-icosanoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72962 chebi_ph7_3 CHEBI:72963 biolink:ChemicalSubstance N-hexadecanoylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72963 chebi_ph7_3 CHEBI:72965 biolink:ChemicalSubstance N-tetracosanoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72965 chebi_ph7_3 GO:0044706 biolink:BiologicalProcess multi-multicellular organism process A multicellular organism process which involves another multicellular organism of the same or different species. go-plus.json http://purl.obolibrary.org/obo/GO_0044706 GO:0044707 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044707 GO:0044704 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044704 GO:0044705 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044705 GO:0044702 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044702 GO:0044703 biolink:BiologicalProcess multi-organism reproductive process A biological process that directly contributes to the process of producing new individuals, involving another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044703 GO:0044700 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044700 GO:0044701 biolink:BiologicalProcess obsolete response to stimulus by single organism OBSOLETE. A response to a stimulus that involves only one organism. go-plus.json response to stimulus by single organism http://purl.obolibrary.org/obo/GO_0044701 GO:0044708 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044708 GO:0044709 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044709 GO:0044710 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044710 GO:0044717 biolink:MolecularActivity 8-hydroxy-dADP phosphatase activity Catalysis of the reaction: 8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate. Reactome:R-HSA-2395965 go-plus.json http://purl.obolibrary.org/obo/GO_0044717 GO:0044718 biolink:BiologicalProcess siderophore transmembrane transport The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore. go-plus.json siderophore membrane transport http://purl.obolibrary.org/obo/GO_0044718 GO:0044715 biolink:MolecularActivity 8-oxo-dGDP phosphatase activity Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate. Reactome:R-HSA-2395879|Reactome:R-HSA-2395873|EC:3.6.1.58|RHEA:32063 go-plus.json http://purl.obolibrary.org/obo/GO_0044715 GO:0044716 biolink:MolecularActivity 8-oxo-GDP phosphatase activity Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate. RHEA:62356|EC:3.6.1.58 go-plus.json http://purl.obolibrary.org/obo/GO_0044716 GO:0044713 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044713 GO:0044714 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044714 GO:0044711 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044711 GO:0044712 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044712 GO:0044719 biolink:BiologicalProcess regulation of imaginal disc-derived wing size Any process that modulates the size of an imaginal disc-derived wing. go-plus.json http://purl.obolibrary.org/obo/GO_0044719 GO:0044720 biolink:BiologicalProcess negative regulation of imaginal disc-derived wing size Any process that reduces the size of an imaginal disc-derived wing. go-plus.json http://purl.obolibrary.org/obo/GO_0044720 GO:0044721 biolink:BiologicalProcess protein import into peroxisome matrix, substrate release The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044721 GO:0044728 biolink:BiologicalProcess DNA methylation or demethylation The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule. go-plus.json changes in DNA methylation http://purl.obolibrary.org/obo/GO_0044728 GO:0030192 biolink:MolecularActivity obsolete Hsp70/Hsc70 protein regulator activity OBSOLETE. Modulates the activity of chaperones of the Hsp70/Hsc70 class. go-plus.json Hsp70/Hsc70 protein regulator activity http://purl.obolibrary.org/obo/GO_0030192 GO:0044729 biolink:MolecularActivity hemi-methylated DNA-binding Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks. go-plus.json double-stranded hemi-methylated DNA binding http://purl.obolibrary.org/obo/GO_0044729 GO:0030193 biolink:BiologicalProcess regulation of blood coagulation Any process that modulates the frequency, rate or extent of blood coagulation. go-plus.json http://purl.obolibrary.org/obo/GO_0030193 GO:0044726 biolink:BiologicalProcess protection of DNA demethylation of female pronucleus The protection of the maternal genome from DNA demethylation in the zygote following fertilization. go-plus.json http://purl.obolibrary.org/obo/GO_0044726 GO:0030190 biolink:MolecularActivity obsolete chaperone inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of a molecular chaperone. go-plus.json chaperone inhibitor activity http://purl.obolibrary.org/obo/GO_0030190 GO:0044727 biolink:BiologicalProcess DNA demethylation of male pronucleus The active DNA demethylation of the paternal genome that takes place before the first cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0044727 GO:0030191 biolink:MolecularActivity obsolete Hsp70/Hsc70 protein inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of chaperones of the Hsp70/Hsc70 class. go-plus.json Hsp70/Hsc70 protein inhibitor activity http://purl.obolibrary.org/obo/GO_0030191 GO:0044724 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044724 GO:0044725 biolink:BiologicalProcess chromatin reprogramming in the zygote The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process. go-plus.json http://purl.obolibrary.org/obo/GO_0044725 GO:0044722 biolink:BiologicalProcess renal phosphate excretion The elimination by an organism of phosphate ions in the urine. go-plus.json renal phosphate ion excretion http://purl.obolibrary.org/obo/GO_0044722 GO:0044723 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044723 GO:0030198 biolink:BiologicalProcess extracellular matrix organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. go-plus.json extracellular matrix organization and biogenesis|extracellular matrix organisation http://purl.obolibrary.org/obo/GO_0030198 goslim_generic|goslim_chembl GO:0030199 biolink:BiologicalProcess collagen fibril organization Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. go-plus.json collagen fibril organisation|fibrillar collagen organization http://purl.obolibrary.org/obo/GO_0030199 NCBITaxon:1521260 biolink:OrganismalEntity Lycopodiopsida go-plus.json clubmosses|club-mosses|club mosses|Lycopodiophyta|Lycopodiidae http://purl.obolibrary.org/obo/NCBITaxon_1521260 GO:0030196 biolink:MolecularActivity cyanide hydratase activity Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide. KEGG_REACTION:R01408|EC:4.2.1.66|RHEA:21720|MetaCyc:CYANIDE-HYDRATASE-RXN go-plus.json formamide hydro-lyase (cyanide-forming)|formamide dehydratase activity|formamide hydro-lyase activity http://purl.obolibrary.org/obo/GO_0030196 GO:0030197 biolink:MolecularActivity extracellular matrix constituent, lubricant activity Functions as a lubricant for an extracellular matrix, such as a mucous membrane. go-plus.json core matrisome|core extracellular matrix http://purl.obolibrary.org/obo/GO_0030197 GO:0030194 biolink:BiologicalProcess positive regulation of blood coagulation Any process that activates or increases the frequency, rate or extent of blood coagulation. go-plus.json upregulation of blood coagulation|up regulation of blood coagulation|activation of blood coagulation|stimulation of blood coagulation|up-regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030194 GO:0030195 biolink:BiologicalProcess negative regulation of blood coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. go-plus.json down regulation of blood coagulation|downregulation of blood coagulation|down-regulation of blood coagulation|inhibition of blood coagulation http://purl.obolibrary.org/obo/GO_0030195 CHEBI:72998 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72998 chebi_ph7_3 CHEBI:72999 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72999 chebi_ph7_3 GO:0044731 biolink:CellularComponent Ost-alpha/Ost-beta complex A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity. go-plus.json (Ost)2 complex|SLC51 complex|Ost alpha-Ost beta complex http://purl.obolibrary.org/obo/GO_0044731 GO:0044732 biolink:CellularComponent mitotic spindle pole body The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0044732 GO:0044730 biolink:MolecularActivity bone sialoprotein binding Binding to a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin. InterPro:IPR008412 go-plus.json bone sialoprotein II binding http://purl.obolibrary.org/obo/GO_0044730 GO:0030181 biolink:BiologicalProcess obsolete sodium:calcium exchange OBSOLETE. Exchange diffusion sodium and calcium ions in which influx of sodium ions to the cytosol drives the efflux of calcium ions from the cell. go-plus.json sodium:calcium exchange http://purl.obolibrary.org/obo/GO_0030181 GO:0044739 biolink:BiologicalProcess positive regulation of acid-sensing ion channel in other organism Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism. go-plus.json positive regulation of ASIC channel in other organism http://purl.obolibrary.org/obo/GO_0044739 GO:0030182 biolink:BiologicalProcess neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0030182 GO:0044737 biolink:BiologicalProcess modulation of acid-sensing ion channel in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism. go-plus.json regulation of ASIC channel in other organism|regulation of acid-sensing ion channel in other organism http://purl.obolibrary.org/obo/GO_0044737 GO:0030180 biolink:BiologicalProcess obsolete solute:solute exchange OBSOLETE. Exchange diffusion of two solutes between the inside and outside of a cell or subcellular compartment, in which movement of one solute down a concentration gradient drives movement of the other solute in the opposite direction. go-plus.json solute:solute exchange http://purl.obolibrary.org/obo/GO_0030180 GO:0044738 biolink:BiologicalProcess negative regulation of acid-sensing ion channel in other organism Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism. go-plus.json negative regulation of ASIC channel in other organism http://purl.obolibrary.org/obo/GO_0044738 GO:0044735 biolink:BiologicalProcess envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism. go-plus.json envenomation resulting in negative regulation of ASIC channel activity in other organism http://purl.obolibrary.org/obo/GO_0044735 GO:0044736 biolink:MolecularActivity acid-sensing ion channel activity Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex. Reactome:R-HSA-2671885|Wikipedia:Acid-sensing_ion_channel go-plus.json ASIC activity http://purl.obolibrary.org/obo/GO_0044736 GO:0044733 biolink:BiologicalProcess envenomation resulting in modulation of acid-sensing ion channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism. go-plus.json envenomation resulting in modulation of ASIC channel activity in other organism http://purl.obolibrary.org/obo/GO_0044733 GO:0044734 biolink:BiologicalProcess envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism. go-plus.json envenomation resulting in positive regulation of ASIC channel activity in other organism http://purl.obolibrary.org/obo/GO_0044734 GO:0030189 biolink:MolecularActivity obsolete chaperone activator activity OBSOLETE. Increases the activity of a molecular chaperone. go-plus.json chaperone activator activity http://purl.obolibrary.org/obo/GO_0030189 GO:0030187 biolink:BiologicalProcess melatonin biosynthetic process The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). go-plus.json melatonin anabolism|melatonin biosynthesis|melatonin synthesis|melatonin formation http://purl.obolibrary.org/obo/GO_0030187 GO:0030188 biolink:MolecularActivity obsolete chaperone regulator activity OBSOLETE. Modulates the activity of a molecular chaperone. go-plus.json chaperone regulator activity http://purl.obolibrary.org/obo/GO_0030188 GO:0030185 biolink:BiologicalProcess nitric oxide transport The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0030185 GO:0030186 biolink:BiologicalProcess melatonin metabolic process The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). go-plus.json melatonin metabolism http://purl.obolibrary.org/obo/GO_0030186 CHEBI:72990 biolink:ChemicalSubstance 3''-deamino-3''-hydroxykanamycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_72990 GO:0030183 biolink:BiologicalProcess B cell differentiation The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. go-plus.json B-lymphocyte differentiation|B cell development|B lymphocyte differentiation|B-cell differentiation http://purl.obolibrary.org/obo/GO_0030183 CHEBI:72991 biolink:ChemicalSubstance dihydrourocanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72991 chebi_ph7_3 GO:0030184 biolink:MolecularActivity nitric oxide transmembrane transporter activity Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0030184 CHEBI:72992 biolink:ChemicalSubstance 3''-deamino-3''-hydroxykanamycin X go-plus.json http://purl.obolibrary.org/obo/CHEBI_72992 GO:0044742 biolink:BiologicalProcess envenomation resulting in modulation of sensory perception of pain in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism. go-plus.json envenomation resulting in regulation of sensory perception of pain in other organism http://purl.obolibrary.org/obo/GO_0044742 GO:0044743 biolink:BiologicalProcess protein transmembrane import into intracellular organelle The directed movement of proteins into an intracellular organelle, across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044743 GO:0044740 biolink:BiologicalProcess negative regulation of sensory perception of pain in other organism A process that negatively regulates the sensory perception of pain in a different organism. go-plus.json inhibition of sensory perception of pain in another organism http://purl.obolibrary.org/obo/GO_0044740 GO:0044741 biolink:BiologicalProcess envenomation resulting in negative regulation of sensory perception of pain in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism. go-plus.json envenomation resulting in inhibition of sensory perception of pain in other organism http://purl.obolibrary.org/obo/GO_0044741 GO:0030170 biolink:MolecularActivity pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0030170 goslim_metagenomics GO:0030171 biolink:MolecularActivity voltage-gated proton channel activity Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage gated proton channel activity|voltage-dependent proton channel activity http://purl.obolibrary.org/obo/GO_0030171 GO:0044748 biolink:MolecularActivity 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA. go-plus.json exonucleolytic trimming to generate 3' end of miRNA http://purl.obolibrary.org/obo/GO_0044748 GO:0044749 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044749 GO:0044746 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044746 GO:0044747 biolink:BiologicalProcess mature miRNA 3'-end processing Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends. go-plus.json miRNA 3'-end processing|miRNA trimming|miRNA 3' end terminal trimming http://purl.obolibrary.org/obo/GO_0044747 GO:0044744 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044744 GO:0044745 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044745 GO:0030178 biolink:BiologicalProcess negative regulation of Wnt signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway. go-plus.json down regulation of frizzled signaling pathway|negative regulation of Wnt receptor signaling pathway|down-regulation of Wnt receptor signaling pathway|inhibition of frizzled signaling pathway|negative regulation of Wnt-activated signaling pathway|negative regulation of frizzled signalling pathway|downregulation of Wnt receptor signaling pathway|down regulation of Wnt receptor signaling pathway|inhibition of Wnt receptor signaling pathway|down-regulation of frizzled signaling pathway|negative regulation of frizzled signaling pathway|negative regulation of Wnt receptor signalling pathway|downregulation of frizzled signaling pathway http://purl.obolibrary.org/obo/GO_0030178 GO:0030179 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030179 GO:0030176 biolink:CellularComponent integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to endoplasmic reticulum membrane|ER integral membrane protein|integral to ER membrane http://purl.obolibrary.org/obo/GO_0030176 GO:0030177 biolink:BiologicalProcess positive regulation of Wnt signaling pathway Any process that activates or increases the frequency, rate or extent of Wnt signal transduction. go-plus.json positive regulation of Wnt-activated signaling pathway|positive regulation of frizzled signalling pathway|upregulation of frizzled signaling pathway|positive regulation of Wnt receptor signaling pathway|up regulation of Wnt receptor signaling pathway|stimulation of frizzled signaling pathway|up-regulation of frizzled signaling pathway|activation of frizzled signaling pathway|upregulation of Wnt receptor signaling pathway|positive regulation of Wnt receptor signalling pathway|positive regulation of frizzled signaling pathway|up regulation of frizzled signaling pathway|stimulation of Wnt receptor signaling pathway|up-regulation of Wnt receptor signaling pathway|activation of Wnt receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030177 GO:0030174 biolink:BiologicalProcess regulation of DNA-dependent DNA replication initiation Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase. go-plus.json DNA replication licensing|regulation of DNA replication initiation|DNA replication licencing http://purl.obolibrary.org/obo/GO_0030174 GO:0030175 biolink:CellularComponent filopodium Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. Wikipedia:Filopodia|NIF_Subcellular:sao1046371754 go-plus.json http://purl.obolibrary.org/obo/GO_0030175 goslim_pir GO:0030172 biolink:MolecularActivity troponin C binding Binding to troponin C, the calcium-binding subunit of the troponin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0030172 GO:0030173 biolink:CellularComponent integral component of Golgi membrane The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json Golgi integral membrane protein|integral to Golgi membrane http://purl.obolibrary.org/obo/GO_0030173 GO:0030169 biolink:MolecularActivity low-density lipoprotein particle binding Binding to a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. go-plus.json LDL binding http://purl.obolibrary.org/obo/GO_0030169 goslim_chembl GO:0044753 biolink:CellularComponent amphisome Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0044753 GO:0044754 biolink:CellularComponent autolysosome A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. NIF_Subcellular:sao8444068431 go-plus.json AVd|degrading autophagic vacuole|autophagolysosome http://purl.obolibrary.org/obo/GO_0044754 GO:0044751 biolink:BiologicalProcess cellular response to human chorionic gonadotropin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus. go-plus.json cellular response to human chorionic gonadotrophin stimulus http://purl.obolibrary.org/obo/GO_0044751 GO:0044752 biolink:BiologicalProcess response to human chorionic gonadotropin Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus. go-plus.json response to human chorionic gonadotropin stimulus http://purl.obolibrary.org/obo/GO_0044752 GO:0044750 biolink:MolecularActivity high-affinity nickel cation transmembrane transporter activity Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json http://purl.obolibrary.org/obo/GO_0044750 GO:0030160 biolink:MolecularActivity synaptic receptor adaptor activity The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule. go-plus.json GKAP/Homer scaffold protein|postsynaptic density scaffold protein|GKAP/Homer scaffold activity http://purl.obolibrary.org/obo/GO_0030160 GO:0044759 biolink:BiologicalProcess negative regulation by symbiont of host synaptic transmission Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044759 GO:0044757 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044757 GO:0044758 biolink:BiologicalProcess modulation by symbiont of host synaptic transmission Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism. go-plus.json regulation by symbiont of host synaptic transmission http://purl.obolibrary.org/obo/GO_0044758 GO:0044755 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044755 GO:0044756 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044756 GO:0030167 biolink:BiologicalProcess proteoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. go-plus.json proteoglycan degradation|proteoglycan breakdown|proteoglycan catabolism http://purl.obolibrary.org/obo/GO_0030167 GO:0030168 biolink:BiologicalProcess platelet activation A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. go-plus.json blood coagulation, platelet activation http://purl.obolibrary.org/obo/GO_0030168 PR:000018461 biolink:Protein interleukin-8 proteolytic cleavage product An interleukin-8 that has been processed by proteolytic cleavage. go-plus.json CXCL8/ClvPrd http://purl.obolibrary.org/obo/PR_000018461 GO:0030165 biolink:MolecularActivity PDZ domain binding Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins. go-plus.json GLGF-domain binding|DHR-domain binding http://purl.obolibrary.org/obo/GO_0030165 GO:0030166 biolink:BiologicalProcess proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. go-plus.json proteoglycan anabolism|proteoglycan synthesis|proteoglycan biosynthesis|proteoglycan formation http://purl.obolibrary.org/obo/GO_0030166 GO:0030163 biolink:BiologicalProcess protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Wikipedia:Protein_catabolism go-plus.json protein catabolism|protein degradation|pheromone catabolism|protein breakdown|multicellular organismal protein catabolic process|pheromone catabolic process http://purl.obolibrary.org/obo/GO_0030163 goslim_candida|goslim_drosophila|goslim_aspergillus|goslim_pombe GO:0030164 biolink:BiologicalProcess protein denaturation Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds. Wikipedia:Denaturation#Protein_denaturation go-plus.json http://purl.obolibrary.org/obo/GO_0030164 GO:0030161 biolink:MolecularActivity obsolete calpain inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue. go-plus.json calpain inhibitor activity http://purl.obolibrary.org/obo/GO_0030161 GO:0030162 biolink:BiologicalProcess regulation of proteolysis Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. go-plus.json regulation of peptidolysis http://purl.obolibrary.org/obo/GO_0030162 GO:0030158 biolink:MolecularActivity protein xylosyltransferase activity Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate. RHEA:50192|MetaCyc:2.4.2.26-RXN|Reactome:R-HSA-1878002|EC:2.4.2.26 go-plus.json peptide O-xylosyltransferase activity|UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity|UDP-D-xylose:core protein xylosyltransferase activity|UDP-xylose-core protein beta-D-xylosyltransferase activity|uridine diphosphoxylose-protein xylosyltransferase activity|UDP-D-xylose:core protein beta-D-xylosyltransferase activity|uridine diphosphoxylose-core protein beta-xylosyltransferase activity|UDP-D-xylose:protein beta-D-xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0030158 CHEBI:150018 biolink:ChemicalSubstance 3-aminobutanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_150018 chebi_ph7_3 GO:0030159 biolink:MolecularActivity signaling receptor complex adaptor activity The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex. go-plus.json receptor signaling complex adaptor activity|receptor signaling complex scaffold activity|receptor signaling complex scaffold protein activity|receptor signalling complex adaptor activity|receptor signalling complex scaffold activity http://purl.obolibrary.org/obo/GO_0030159 GO:0044764 biolink:BiologicalProcess multi-organism cellular process Any process that is carried out at the cellular level which involves another organism of the same or different species. go-plus.json http://purl.obolibrary.org/obo/GO_0044764 GO:0044765 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044765 GO:0044762 biolink:BiologicalProcess negative regulation by symbiont of host neurotransmitter secretion Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044762 GO:0005198 biolink:MolecularActivity structural molecule activity The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0005198 goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_candida|goslim_yeast|goslim_plant|goslim_pir|goslim_aspergillus|goslim_generic GO:0044763 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044763 GO:0005199 biolink:MolecularActivity structural constituent of cell wall The action of a molecule that contributes to the structural integrity of a cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0005199 GO:0044760 biolink:BiologicalProcess modulation by symbiont of host cholinergic synaptic transmission Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism. go-plus.json regulation by symbiont of host cholinergic synaptic transmission http://purl.obolibrary.org/obo/GO_0044760 GO:0044761 biolink:BiologicalProcess negative regulation by symbiont of host cholinergic synaptic transmission Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044761 GO:0005194 biolink:MolecularActivity obsolete cell adhesion molecule activity OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix. go-plus.json cell adhesion molecule activity http://purl.obolibrary.org/obo/GO_0005194 CHEBI:140691 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_140691 chebi_ph7_3 GO:0044768 biolink:BiologicalProcess NMS complex assembly The aggregation, arrangement and bonding together of a set of components to form an NMS complex. The NMS complex results from the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) and is required for kinetochore assembly. go-plus.json NMS complex association involved in chromosome segregation|Ndc80-MIND-Spc7 complex formation|KMN network assembly involved in chromosome segregation|KMN complex interaction involved in chromosome segregation|KNL-1-Mis12-Ndc80 formation|KMN kinetochore network assembly|NMS complex assembly involved in kinetochore assembly|KMN kinetochore network formation|KNL-1-Mis12-Ndc80 assembly|NMS complex formation|Ndc80-MIND-Spc7 complex assembly http://purl.obolibrary.org/obo/GO_0044768 GO:0044769 biolink:MolecularActivity ATPase activity, coupled to transmembrane movement of ions, rotational mechanism Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0044769 GO:0044766 biolink:BiologicalProcess multi-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044766 GO:0044767 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044767 GO:0030156 biolink:MolecularActivity benzodiazepine receptor binding Binding to a peripheral benzodiazepine receptor (PBR). go-plus.json diazepam binding inhibitor activity|benzodiazepine receptor ligand http://purl.obolibrary.org/obo/GO_0030156 GO:0030157 biolink:BiologicalProcess pancreatic juice secretion The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. go-plus.json http://purl.obolibrary.org/obo/GO_0030157 GO:0030154 biolink:BiologicalProcess cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Wikipedia:Cellular_differentiation go-plus.json http://purl.obolibrary.org/obo/GO_0030154 goslim_drosophila|goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_plant CHEBI:150013 biolink:ChemicalSubstance emodin anthrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_150013 chebi_ph7_3 GO:0030155 biolink:BiologicalProcess regulation of cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. go-plus.json cell adhesion receptor regulator activity http://purl.obolibrary.org/obo/GO_0030155 GO:0030152 biolink:BiologicalProcess bacteriocin biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. go-plus.json bacteriocin anabolism|bacteriocin synthesis|bacteriocin formation|bacteriocin biosynthesis http://purl.obolibrary.org/obo/GO_0030152 GO:0030153 biolink:BiologicalProcess bacteriocin immunity A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. go-plus.json http://purl.obolibrary.org/obo/GO_0030153 GO:0030150 biolink:BiologicalProcess protein import into mitochondrial matrix The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. go-plus.json protein transport into mitochondrial matrix|mitochondrial translocation|mitochondrial matrix protein import http://purl.obolibrary.org/obo/GO_0030150 GO:0030151 biolink:MolecularActivity molybdenum ion binding Binding to a molybdenum ion (Mo). go-plus.json molybdenum binding|Mo ion binding http://purl.obolibrary.org/obo/GO_0030151 PR:000018435 biolink:Protein interleukin-16 proteolytic cleavage product An interleukin-16 that has been processed by proteolytic cleavage. go-plus.json IL16/ClvPrd http://purl.obolibrary.org/obo/PR_000018435 GO:0030149 biolink:BiologicalProcess sphingolipid catabolic process The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). go-plus.json sphingolipid catabolism|sphingolipid breakdown|sphingolipid degradation http://purl.obolibrary.org/obo/GO_0030149 GO:0030147 biolink:BiologicalProcess obsolete natriuresis OBSOLETE. The process of renal sodium excretion. Wikipedia:Natriuresis go-plus.json natriuresis http://purl.obolibrary.org/obo/GO_0030147 PR:000018438 biolink:Protein interleukin-18 proteolytic cleavage product An interleukin-18 that has been processed by proteolytic cleavage. go-plus.json IL18/ClvPrd http://purl.obolibrary.org/obo/PR_000018438 GO:0030148 biolink:BiologicalProcess sphingolipid biosynthetic process The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). MetaCyc:PWY-5129 go-plus.json sphingolipid biosynthesis|sphingolipid anabolism|sphingolipid synthesis|sphingolipid formation http://purl.obolibrary.org/obo/GO_0030148 GO:0044775 biolink:CellularComponent DNA polymerase III, beta sliding clamp processivity factor complex A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species. go-plus.json http://purl.obolibrary.org/obo/GO_0044775 GO:0044776 biolink:CellularComponent DNA polymerase III, core complex The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities. go-plus.json http://purl.obolibrary.org/obo/GO_0044776 GO:0044773 biolink:BiologicalProcess mitotic DNA damage checkpoint signaling A signal transduction process involved in mitotic DNA damage checkpoint. go-plus.json intracellular signaling cascade involved in mitotic DNA damage checkpoint|mitotic DNA damage checkpoint|intracellular signal transduction pathway involved in mitotic DNA damage checkpoint|intracellular signaling pathway involved in mitotic DNA damage checkpoint|signal transduction involved in mitotic DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0044773 GO:0044774 biolink:BiologicalProcess mitotic DNA integrity checkpoint signaling A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction. go-plus.json signal transduction involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint|intracellular signal transduction involved in topo II checkpoint|signal transduction via intracellular signaling cascade involved in topo II checkpoint|intracellular signaling pathway involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in topo II checkpoint|intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling pathway involved in topo II checkpoint|mitotic DNA integrity checkpoint|intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling cascade involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in topoisomerase II checkpoint|intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling pathway involved in topoisomerase II checkpoint|intracellular signaling cascade involved in topo II checkpoint|intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling chain involved in mitotic DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_0044774 GO:0044771 biolink:BiologicalProcess meiotic cell cycle phase transition The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase. go-plus.json cell cycle transition http://purl.obolibrary.org/obo/GO_0044771 GO:0044772 biolink:BiologicalProcess mitotic cell cycle phase transition The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase. go-plus.json http://purl.obolibrary.org/obo/GO_0044772 goslim_pombe GO:0044770 biolink:BiologicalProcess cell cycle phase transition The cell cycle process by which a cell commits to entering the next cell cycle phase. go-plus.json cell cycle transition http://purl.obolibrary.org/obo/GO_0044770 GO:0044779 biolink:BiologicalProcess meiotic spindle checkpoint signaling A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle. go-plus.json intracellular signaling cascade involved in meiotic spindle checkpoint|intracellular signal transduction pathway involved in meiotic spindle checkpoint|intracellular signaling pathway involved in meiotic spindle checkpoint|intracellular signal transduction involved in meiotic spindle checkpoint|meiotic spindle checkpoint http://purl.obolibrary.org/obo/GO_0044779 GO:0044777 biolink:CellularComponent single-stranded DNA-binding protein complex A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair. go-plus.json SSB complex http://purl.obolibrary.org/obo/GO_0044777 GO:0044778 biolink:BiologicalProcess meiotic DNA integrity checkpoint signaling A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction. go-plus.json meiotic DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_0044778 GO:0030145 biolink:MolecularActivity manganese ion binding Binding to a manganese ion (Mn). go-plus.json Mn binding|manganese binding http://purl.obolibrary.org/obo/GO_0030145 GO:0030146 biolink:BiologicalProcess obsolete diuresis OBSOLETE. The process of renal water excretion. Wikipedia:Diuresis go-plus.json renal water excretion|positive regulation of renal water excretion|diuresis http://purl.obolibrary.org/obo/GO_0030146 GO:0030143 biolink:CellularComponent COPI-coated inter-Golgi transport vesicle A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack). NIF_Subcellular:sao1382918459 go-plus.json inter-Golgi transport constitutive secretory pathway transport vesicle http://purl.obolibrary.org/obo/GO_0030143 GO:0030144 biolink:MolecularActivity alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors. Reactome:R-HSA-975916|Reactome:R-HSA-9696980|RHEA:16921|MetaCyc:2.4.1.155-RXN|EC:2.4.1.155 go-plus.json GnTV activity|alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity|alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase V activity http://purl.obolibrary.org/obo/GO_0030144 GO:0030141 biolink:CellularComponent secretory granule A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. go-plus.json secretory vesicle http://purl.obolibrary.org/obo/GO_0030141 GO:0030142 biolink:CellularComponent COPI-coated Golgi to ER transport vesicle A vesicle that mediates transport from the Golgi to the endoplasmic reticulum. go-plus.json Golgi-ER transport vesicle|Golgi-endoplasmic reticulum transport vesicle|Golgi to endoplasmic reticulum transport vesicle|Golgi to ER constitutive secretory pathway transport vesicle|retrograde transport vesicle http://purl.obolibrary.org/obo/GO_0030142 GO:0030140 biolink:CellularComponent trans-Golgi network transport vesicle A vesicle that mediates transport between the trans-Golgi network and other parts of the cell. go-plus.json trans-Golgi network constitutive secretory pathway transport vesicle|TGN transport vesicle http://purl.obolibrary.org/obo/GO_0030140 CHEBI:23953 biolink:ChemicalSubstance erythromycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23953 CHEBI:47921 biolink:ChemicalSubstance cis-2-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47921 chebi_ph7_3 CHEBI:47923 biolink:ChemicalSubstance tripeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_47923 UBERON:0004383 biolink:AnatomicalEntity epiphysis of tibia An epiphysis that is part of a tibia [Automatically generated definition]. go-plus.json tibial epiphysis http://purl.obolibrary.org/obo/UBERON_0004383 UBERON:0004384 biolink:AnatomicalEntity epiphysis of femur An epiphysis that is part of a femur [Automatically generated definition]. go-plus.json femoral epiphysis http://purl.obolibrary.org/obo/UBERON_0004384 UBERON:0004381 biolink:AnatomicalEntity skeleton of limb The collection of all skeletal elements in an individual limb. go-plus.json set of bones of limb|limb skeleton|free limb skeleton http://purl.obolibrary.org/obo/UBERON_0004381 UBERON:0004382 biolink:AnatomicalEntity epiphysis of humerus An epiphysis that is part of a humerus [Automatically generated definition]. go-plus.json humeral epiphysis http://purl.obolibrary.org/obo/UBERON_0004382 UBERON:0004380 biolink:AnatomicalEntity proximal epiphysis An epiphysis that is on the proximal side of the bone. go-plus.json proximal end of long bone http://purl.obolibrary.org/obo/UBERON_0004380 CHEBI:23957 biolink:ChemicalSubstance erythroses go-plus.json http://purl.obolibrary.org/obo/CHEBI_23957 CHEBI:47925 biolink:ChemicalSubstance 3-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47925 CHEBI:23958 biolink:ChemicalSubstance erythrulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23958 chebi_ph7_3 CHEBI:23955 biolink:ChemicalSubstance erythronolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23955 CHEBI:47927 biolink:ChemicalSubstance 3-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47927 chebi_ph7_3 CHEBI:23956 biolink:ChemicalSubstance erythrose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23956 CHEBI:47928 biolink:ChemicalSubstance trans-3-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47928 chebi_ph7_3 UBERON:0004389 biolink:AnatomicalEntity epiphysis of metatarsal bone An epiphysis that is part of a metatarsal bone [Automatically generated definition]. go-plus.json epiphysis of metatarsal|metatarsal bone epiphysis|metatarsal epiphysis http://purl.obolibrary.org/obo/UBERON_0004389 UBERON:0004387 biolink:AnatomicalEntity epiphysis of phalanx of manus An epiphysis that is part of a phalanx of a manus [Automatically generated definition]. go-plus.json epiphysis of phalanx of hand|epiphysis of phalanx of finger http://purl.obolibrary.org/obo/UBERON_0004387 UBERON:0004388 biolink:AnatomicalEntity epiphysis of fibula An epiphysis that is part of a fibula [Automatically generated definition]. go-plus.json fibula epiphysis http://purl.obolibrary.org/obo/UBERON_0004388 CHEBI:23965 biolink:ChemicalSubstance estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23965 chebi_ph7_3 CHEBI:47910 biolink:ChemicalSubstance S-substituted L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47910 CHEBI:47911 biolink:ChemicalSubstance S-substituted N-acetyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47911 CHEBI:47912 biolink:ChemicalSubstance S-organyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47912 UBERON:0004374 biolink:AnatomicalEntity vitelline vasculature vascular network that is connected to the yolk sac. go-plus.json vitelline system|omphalomesenteric system|vitelline bloos vessel system http://purl.obolibrary.org/obo/UBERON_0004374 UBERON:0004375 biolink:AnatomicalEntity bone of free limb or fin A bone that is part of an appendage [Automatically generated definition]. go-plus.json bone of appendage|appendage bone|bone of free segment of appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0004375 UBERON:0004370 biolink:AnatomicalEntity anterior limiting lamina of cornea A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane. go-plus.json anterior elastic lamina|Bowman's membrane|Reichert's membrane|anterior limiting lamina|Bowman's anterior elastic lamina|lamina limitans anterior corneae|Bowman's layer|lamina limitans anterior (cornea)|anterior limiting lamina of cornea|anterior limiting membrane http://purl.obolibrary.org/obo/UBERON_0004370 CHEBI:47913 biolink:ChemicalSubstance S-hydrocarbyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47913 CHEBI:47914 biolink:ChemicalSubstance S-prenyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47914 NCBITaxon:54124 biolink:OrganismalEntity Neodiplogasteridae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_54124 CHEBI:23966 biolink:ChemicalSubstance estrane go-plus.json http://purl.obolibrary.org/obo/CHEBI_23966 chebi_ph7_3 CHEBI:47915 biolink:ChemicalSubstance S-alkyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47915 chebi_ph7_3 CHEBI:47916 biolink:ChemicalSubstance flavonoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47916 UBERON:0004378 biolink:AnatomicalEntity proximal metaphysis A metaphysis that is in the proximal side of a diaphysis. go-plus.json proximal diaphyseal end of long bone http://purl.obolibrary.org/obo/UBERON_0004378 CHEBI:47917 biolink:ChemicalSubstance 1-ribosylbenzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_47917 UBERON:0004379 biolink:AnatomicalEntity distal epiphysis An epiphysis that is on the distal side of the bone. go-plus.json distal end of long bone http://purl.obolibrary.org/obo/UBERON_0004379 UBERON:0004376 biolink:AnatomicalEntity fin bone A bone that is part of a fin [Automatically generated definition]. go-plus.json bone of fin http://purl.obolibrary.org/obo/UBERON_0004376 NCBITaxon:54125 biolink:OrganismalEntity Pristionchus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_54125 UBERON:0004377 biolink:AnatomicalEntity distal metaphysis A metaphysis that is in the distal side of a diaphysis. go-plus.json distal diaphyseal end of long bone http://purl.obolibrary.org/obo/UBERON_0004377 NCBITaxon:54126 biolink:OrganismalEntity Pristionchus pacificus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_54126 CHEBI:23931 biolink:ChemicalSubstance epoxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23931 CHEBI:72900 biolink:ChemicalSubstance cardiolipin 72:8(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72900 chebi_ph7_3 CHEBI:47901 biolink:ChemicalSubstance alkanesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47901 UBERON:0004363 biolink:AnatomicalEntity pharyngeal arch artery One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP] go-plus.json branchial aortic arches|branchial arch artery|a. arcuum pharyngeorum|embryonic aortic arch artery|pharyngeal arch artery|aortic arches|aortic arch artery|pharyngeal arch artery|arteriae arcuum pharyngeorum|pharyngeal arch arteries|PAA|aortic arch|branchial aortic arches http://purl.obolibrary.org/obo/UBERON_0004363 UBERON:0004364 biolink:AnatomicalEntity ectoplacental cone thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta go-plus.json placenta - ectoplacental cone|epamniotic cone http://purl.obolibrary.org/obo/UBERON_0004364 UBERON:0004362 biolink:AnatomicalEntity pharyngeal arch 1 The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries go-plus.json 1st visceral arch|1st pharyngeal arch|first pharyngeal arch|1st arch|branchial arch 1|arcus pharyngeus primus|first branchial arch|visceral arch 1|first visceral arch|mandibular arch http://purl.obolibrary.org/obo/UBERON_0004362 CHEBI:47902 biolink:ChemicalSubstance idopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47902 CHEBI:47903 biolink:ChemicalSubstance L-idopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47903 CHEBI:47904 biolink:ChemicalSubstance 4-maleylacetoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47904 CHEBI:47905 biolink:ChemicalSubstance coniferyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47905 chebi_ph7_3 UBERON:0004367 biolink:AnatomicalEntity Descemet's membrane A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. go-plus.json Descemet membrane|posterior limiting membrane|posterior limiting lamina of cornea|lamina limitans posterior corneae|lamina limitans posterior|Descemet's posterior elastic lamina|posterior limiting lamina http://purl.obolibrary.org/obo/UBERON_0004367 CHEBI:47907 biolink:ChemicalSubstance 3-oxo-Delta(5)-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47907 chebi_ph7_3 UBERON:0004365 biolink:AnatomicalEntity vitelline blood vessel blood vessel that is connected to the yolk sac. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004365 CHEBI:47908 biolink:ChemicalSubstance alkanethiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47908 chebi_ph7_3 CHEBI:47909 biolink:ChemicalSubstance 3-oxo-Delta(4) steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47909 chebi_ph7_3 NCBITaxon:188709 biolink:OrganismalEntity Thermotogaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_188709 CHEBI:23943 biolink:ChemicalSubstance ergot alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23943 UBERON:0004356 biolink:AnatomicalEntity apical ectodermal ridge multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. go-plus.json crista ectodermalis apicalis|AER|apical epidermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 UBERON:0004357 biolink:AnatomicalEntity paired limb/fin bud An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. go-plus.json limb - fin bud|paired appendage bud|paired limb/fin bud http://purl.obolibrary.org/obo/UBERON_0004357 NCBITaxon:188708 biolink:OrganismalEntity Thermotogae go-plus.json Togobacteria|Thermotogae http://purl.obolibrary.org/obo/NCBITaxon_188708 CHEBI:23948 biolink:ChemicalSubstance erythro-3-methylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23948 CHEBI:5924 biolink:ChemicalSubstance EC 3.4.21.* (serine endopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_5924 CHEBI:23924 biolink:ChemicalSubstance enzyme inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_23924 CHEBI:23925 biolink:ChemicalSubstance (+)-5-epi-aristolochene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23925 chebi_ph7_3 CHEBI:23929 biolink:ChemicalSubstance episterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23929 chebi_ph7_3 CHEBI:72944 biolink:ChemicalSubstance 3''-deamino-3''-hydroxykanamycin B(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72944 chebi_ph7_3 CHEBI:72945 biolink:ChemicalSubstance 3''-deamino-3''-hydroxykanamycin C(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72945 chebi_ph7_3 CHEBI:72946 biolink:ChemicalSubstance 3''-deamino-3''-hydroxykanamycin X(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72946 chebi_ph7_3 CHEBI:72947 biolink:ChemicalSubstance kanamycin D(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72947 chebi_ph7_3 CHEBI:72948 biolink:ChemicalSubstance deoxybrevianamide E go-plus.json http://purl.obolibrary.org/obo/CHEBI_72948 chebi_ph7_3 CHEBI:72949 biolink:ChemicalSubstance chanoclavine-I(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72949 chebi_ph7_3 CHEBI:72950 biolink:ChemicalSubstance (7,8-dihydropterin-6-yl)methyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72950 chebi_ph7_3 CHEBI:72951 biolink:ChemicalSubstance N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72951 chebi_ph7_3 CHEBI:72952 biolink:ChemicalSubstance 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72952 CHEBI:72956 biolink:ChemicalSubstance N-dodecanoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72956 chebi_ph7_3 CHEBI:72957 biolink:ChemicalSubstance N-tetradecanoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72957 chebi_ph7_3 CHEBI:72959 biolink:ChemicalSubstance N-hexadecanoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72959 chebi_ph7_3 UBERON:0004390 biolink:AnatomicalEntity epiphysis of metacarpal bone An epiphysis that is part of a metacarpal bone [Automatically generated definition]. go-plus.json metacarpal bone epiphysis|epiphysis of metacarpal|metacarpal epiphysis http://purl.obolibrary.org/obo/UBERON_0004390 CHEBI:23902 biolink:ChemicalSubstance icosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23902 CHEBI:23906 biolink:ChemicalSubstance monoatomic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_23906 CHEBI:23905 biolink:ChemicalSubstance monoatomic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_23905 CHEBI:57329 biolink:ChemicalSubstance 2,4-dichlorobenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57329 chebi_ph7_3 GO:0019739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019739 CHEBI:33352 biolink:ChemicalSubstance manganese group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33352 CHEBI:57320 biolink:ChemicalSubstance citramalyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57320 chebi_ph7_3 GO:0019737 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019737 CHEBI:140714 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_140714 chebi_ph7_3 GO:0019738 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019738 GO:0019735 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019735 CHEBI:33356 biolink:ChemicalSubstance iron group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33356 GO:0019736 biolink:BiologicalProcess peptidyl-sarcosine incorporation The incorporation of sarcosine (N-methylglycine) into non-coded peptides. RESID:AA0063 go-plus.json http://purl.obolibrary.org/obo/GO_0019736 GO:0019733 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019733 CHEBI:33358 biolink:ChemicalSubstance cobalt group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33358 PATO:0002266 biolink:OntologyClass 3-D shape A shape that inheres in a 3 dimensional entity. go-plus.json http://purl.obolibrary.org/obo/PATO_0002266 GO:0019734 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019734 GO:0019731 biolink:BiologicalProcess antibacterial humoral response An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0019731 CHEBI:57327 biolink:ChemicalSubstance (S)-methylmalonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57327 chebi_ph7_3 GO:0019732 biolink:BiologicalProcess antifungal humoral response An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0019732 CHEBI:57328 biolink:ChemicalSubstance 3'-dephospho-CoA(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57328 chebi_ph7_3 CHEBI:57325 biolink:ChemicalSubstance (E,E)-piperonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57325 chebi_ph7_3 GO:0019730 biolink:BiologicalProcess antimicrobial humoral response An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0019730 CHEBI:57326 biolink:ChemicalSubstance (R)-methylmalonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57326 chebi_ph7_3 UBERON:0004301 biolink:AnatomicalEntity middle phalanx A phalanx located between proximal and distal phalanges. go-plus.json phalanx II|penultimate phalanx|medial phalanx|intermediate phalanx|phalanx 2 http://purl.obolibrary.org/obo/UBERON_0004301 CHEBI:57323 biolink:ChemicalSubstance cis-tetradec-11-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57323 chebi_ph7_3 UBERON:0004302 biolink:AnatomicalEntity proximal phalanx Proximal-most phalanx within a digit. go-plus.json phalanx I|proximal-most phalanx|phalanx 1 http://purl.obolibrary.org/obo/UBERON_0004302 CHEBI:57324 biolink:ChemicalSubstance cinnamoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57324 chebi_ph7_3 CHEBI:57321 biolink:ChemicalSubstance (3S)-citryl-CoA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57321 chebi_ph7_3 CHEBI:33350 biolink:ChemicalSubstance chromium group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33350 UBERON:0004300 biolink:AnatomicalEntity distal phalanx Distal-most phalanx within a digit. go-plus.json phalanx distalis|phalanx distalis|terminal phalanx|ungual phalanx http://purl.obolibrary.org/obo/UBERON_0004300 CHEBI:57322 biolink:ChemicalSubstance trans-tetradec-11-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57322 chebi_ph7_3 GO:0005109 biolink:MolecularActivity frizzled binding Binding to a frizzled (fz) receptor. go-plus.json frizzled-2 binding|fz binding|fz2 ligand|fz2 binding|frizzled ligand|frizzled-2 ligand|fz ligand http://purl.obolibrary.org/obo/GO_0005109 goslim_chembl CHEBI:47993 biolink:ChemicalSubstance N,N-dihydroxy-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_47993 CHEBI:47994 biolink:ChemicalSubstance L-tryptophan derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_47994 GO:0005107 biolink:MolecularActivity obsolete GPI-linked ephrin OBSOLETE. (Was not defined before being made obsolete). go-plus.json GPI-linked ephrin http://purl.obolibrary.org/obo/GO_0005107 CHEBI:47995 biolink:ChemicalSubstance hydroxy-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_47995 GO:0005108 biolink:MolecularActivity obsolete transmembrane ephrin OBSOLETE. (Was not defined before being made obsolete). go-plus.json transmembrane ephrin http://purl.obolibrary.org/obo/GO_0005108 CHEBI:47996 biolink:ChemicalSubstance dihydroxy-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_47996 CHEBI:47997 biolink:ChemicalSubstance D-tryptophan derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_47997 GO:0005105 biolink:MolecularActivity type 1 fibroblast growth factor receptor binding Binding to a type 1 fibroblast growth factor receptor (FGFR1). go-plus.json breathless ligand|type 1 fibroblast growth factor receptor ligand|FGFR1 ligand|breathless binding|FGFR1 binding http://purl.obolibrary.org/obo/GO_0005105 GO:0005106 biolink:MolecularActivity obsolete ephrin OBSOLETE. A class of proteins that interact with the ephrin receptors. go-plus.json ephrin http://purl.obolibrary.org/obo/GO_0005106 CHEBI:57318 biolink:ChemicalSubstance (S)-3-hydroxyacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57318 chebi_ph7_3 GO:0005103 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005103 GO:0005104 biolink:MolecularActivity fibroblast growth factor receptor binding Binding to a fibroblast growth factor receptor (FGFR). go-plus.json FGF receptor binding|fibroblast growth factor receptor ligand|fibroblast growth factor|FGFR binding|FGFR ligand http://purl.obolibrary.org/obo/GO_0005104 CHEBI:57319 biolink:ChemicalSubstance (R)-3-hydroxyacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57319 chebi_ph7_3 GO:0005101 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005101 GO:0005102 biolink:MolecularActivity signaling receptor binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. Wikipedia:Ligand_(biochemistry) go-plus.json receptor ligand|receptor binding|receptor-associated protein activity http://purl.obolibrary.org/obo/GO_0005102 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_plant GO:0005100 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005100 CHEBI:47990 biolink:ChemicalSubstance N-hydroxy-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47990 CHEBI:47991 biolink:ChemicalSubstance N,N-dihydroxy-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47991 CHEBI:47992 biolink:ChemicalSubstance N-hydroxy-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_47992 CHEBI:5975 biolink:ChemicalSubstance iron chelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_5975 CHEBI:33364 biolink:ChemicalSubstance platinum go-plus.json http://purl.obolibrary.org/obo/CHEBI_33364 chebi_ph7_3 GO:0019748 biolink:BiologicalProcess secondary metabolic process The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. Wikipedia:Secondary_metabolism go-plus.json secondary metabolite metabolism|secondary metabolism|secondary metabolite metabolic process http://purl.obolibrary.org/obo/GO_0019748 goslim_pir|goslim_plant|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl CHEBI:33365 biolink:ChemicalSubstance platinum group metal atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33365 CHEBI:33366 biolink:ChemicalSubstance copper group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33366 GO:0019749 biolink:BiologicalProcess cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0019749 GO:0019746 biolink:BiologicalProcess hopanoid biosynthetic process The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus. go-plus.json hopanoid anabolism|hopanoid synthesis|hopanoid formation|hopanoid biosynthesis http://purl.obolibrary.org/obo/GO_0019746 GO:0019747 biolink:BiologicalProcess regulation of isoprenoid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids. go-plus.json regulation of isoprenoid metabolism http://purl.obolibrary.org/obo/GO_0019747 GO:0019744 biolink:BiologicalProcess hopanoid metabolic process The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus. go-plus.json hopanoid metabolism http://purl.obolibrary.org/obo/GO_0019744 GO:0019745 biolink:BiologicalProcess pentacyclic triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings. go-plus.json pentacyclic triterpenoid biosynthesis|pentacyclic triterpenoid anabolism|pentacyclic triterpenoid synthesis|pentacyclic triterpenoid formation http://purl.obolibrary.org/obo/GO_0019745 CHEBI:57316 biolink:ChemicalSubstance (S)-3-hydroxybutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57316 chebi_ph7_3 GO:0019742 biolink:BiologicalProcess pentacyclic triterpenoid metabolic process The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings. go-plus.json pentacyclic triterpenoid metabolism http://purl.obolibrary.org/obo/GO_0019742 CHEBI:57317 biolink:ChemicalSubstance (3S)-3-carboxy-3-hydroxypropanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57317 chebi_ph7_3 GO:0019743 biolink:BiologicalProcess hopanoid catabolic process The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus. go-plus.json hopanoid catabolism|hopanoid degradation|hopanoid breakdown http://purl.obolibrary.org/obo/GO_0019743 CHEBI:57314 biolink:ChemicalSubstance (2S)-2-methylacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57314 chebi_ph7_3 GO:0019740 biolink:BiologicalProcess nitrogen utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0019740 GO:0019741 biolink:BiologicalProcess pentacyclic triterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings. go-plus.json pentacyclic triterpenoid breakdown|pentacyclic triterpenoid catabolism|pentacyclic triterpenoid degradation http://purl.obolibrary.org/obo/GO_0019741 CHEBI:57315 biolink:ChemicalSubstance (R)-3-hydroxybutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57315 chebi_ph7_3 CHEBI:57312 biolink:ChemicalSubstance (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57312 chebi_ph7_3 CHEBI:57313 biolink:ChemicalSubstance (2R)-2-methylacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57313 chebi_ph7_3 CHEBI:57310 biolink:ChemicalSubstance presqualene diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57310 chebi_ph7_3 CHEBI:57311 biolink:ChemicalSubstance (1-hydroxycyclohexyl)acetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57311 chebi_ph7_3 CHEBI:33362 biolink:ChemicalSubstance nickel group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33362 CHEBI:47982 biolink:ChemicalSubstance pantetheine 4'-phosphate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_47982 chebi_ph7_3 CHEBI:47985 biolink:ChemicalSubstance enol ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_47985 chebi_ph7_3 CHEBI:57309 biolink:ChemicalSubstance coproporphyrinogen III(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57309 chebi_ph7_3 CHEBI:47987 biolink:ChemicalSubstance 2-amino-2-deoxy-D-glucopyranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47987 CHEBI:57307 biolink:ChemicalSubstance protoporphyrinogen(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57307 chebi_ph7_3 CHEBI:57308 biolink:ChemicalSubstance uroporphyrinogen III(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57308 chebi_ph7_3 CHEBI:47989 biolink:ChemicalSubstance enamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47989 CHEBI:33338 biolink:ChemicalSubstance aryl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33338 CHEBI:47980 biolink:ChemicalSubstance threo-3-methyl-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47980 GO:0019719 biolink:CellularComponent obsolete smooth microsome OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes. go-plus.json smooth microsome http://purl.obolibrary.org/obo/GO_0019719 GO:0019717 biolink:CellularComponent obsolete synaptosome OBSOLETE. Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma. Wikipedia:Synaptosome go-plus.json synaptosome http://purl.obolibrary.org/obo/GO_0019717 GO:0019718 biolink:CellularComponent obsolete rough microsome OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside. go-plus.json rough microsome http://purl.obolibrary.org/obo/GO_0019718 GO:0019715 biolink:BiologicalProcess peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16). RESID:AA0027 go-plus.json http://purl.obolibrary.org/obo/GO_0019715 GO:0019716 biolink:BiologicalProcess N-terminal peptidyl-alanine monomethylation The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine. RESID:AA0061 go-plus.json http://purl.obolibrary.org/obo/GO_0019716 GO:0019713 biolink:BiologicalProcess peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine The coupled methyl esterification and deamidation of peptidyl-glutamine. RESID:AA0072 go-plus.json peptidyl-L-glutamic acid 5-methyl ester formation from glutamine|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamine|peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamine http://purl.obolibrary.org/obo/GO_0019713 GO:0019714 biolink:BiologicalProcess peptidyl-glutamine esterification The addition of an ester group to a glutamine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0019714 GO:0019711 biolink:BiologicalProcess peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid. go-plus.json peptidyl-beta-carboxyaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid formation from peptidyl-aspartic acid http://purl.obolibrary.org/obo/GO_0019711 GO:0019712 biolink:BiologicalProcess peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamic acid The methyl esterification of peptidyl-glutamic acid. RESID:AA0072 go-plus.json peptidyl-L-glutamic acid 5-methyl ester formation from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamic acid http://purl.obolibrary.org/obo/GO_0019712 CHEBI:57305 biolink:ChemicalSubstance glycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57305 chebi_ph7_3 GO:0019710 biolink:BiologicalProcess peptidyl-asparagine methylation The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine. RESID:AA0070|RESID:AA0311 go-plus.json http://purl.obolibrary.org/obo/GO_0019710 CHEBI:57306 biolink:ChemicalSubstance protoporphyrin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57306 chebi_ph7_3 CHEBI:57303 biolink:ChemicalSubstance deoxyamidinoproclavaminic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57303 chebi_ph7_3 CHEBI:57304 biolink:ChemicalSubstance N(2)-(2-carboxyethyl)-L-arginine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57304 chebi_ph7_3 CHEBI:57301 biolink:ChemicalSubstance dihydroclavaminic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57301 chebi_ph7_3 CHEBI:57302 biolink:ChemicalSubstance proclavaminic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57302 chebi_ph7_3 CHEBI:57300 biolink:ChemicalSubstance clavaminic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57300 chebi_ph7_3 CHEBI:47977 biolink:ChemicalSubstance 2-amino-2-deoxy-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47977 CHEBI:47978 biolink:ChemicalSubstance N-acetylmuramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47978 GO:0019728 biolink:BiologicalProcess peptidyl-allysine oxidation to 2-aminoadipic acid The oxidation of allysine to 2-aminoadipic acid. RESID:AA0370 go-plus.json http://purl.obolibrary.org/obo/GO_0019728 GO:0019729 biolink:BiologicalProcess peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. RESID:AA0189 go-plus.json biosynthetic process of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0019729 GO:0019726 biolink:MolecularActivity mevaldate reductase (NADPH) activity Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH. KEGG_REACTION:R02247|MetaCyc:MEVALDATE-REDUCTASE-NADPH-RXN|RHEA:20193|EC:1.1.1.33 go-plus.json mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase|(R)-mevalonate:NADP+ oxidoreductase http://purl.obolibrary.org/obo/GO_0019726 GO:0019727 biolink:MolecularActivity mevaldate reductase (NAD+) activity Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH. KEGG_REACTION:R02246|RHEA:13221|EC:1.1.1.32|MetaCyc:MEVALDATE-REDUCTASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0019727 GO:0019724 biolink:BiologicalProcess B cell mediated immunity Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. go-plus.json B-cell mediated immunity|B-lymphocyte mediated immunity|B-lymphocyte mediated immune effector process|B-cell mediated immune effector process|B lymphocyte mediated immunity|B lymphocyte mediated immune effector process http://purl.obolibrary.org/obo/GO_0019724 NCBITaxon:188787 biolink:OrganismalEntity Deinococci go-plus.json Hadobacteria http://purl.obolibrary.org/obo/NCBITaxon_188787 GO:0019725 biolink:BiologicalProcess cellular homeostasis Any process involved in the maintenance of an internal steady state at the level of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0019725 goslim_candida|goslim_plant|goslim_aspergillus GO:0019722 biolink:BiologicalProcess calcium-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. Wikipedia:Calcium_signaling go-plus.json calcium ion signaling|calcium-mediated signalling|calcium signaling|calcium signalling http://purl.obolibrary.org/obo/GO_0019722 CHEBI:33347 biolink:ChemicalSubstance vanadium group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33347 GO:0019723 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019723 GO:0019720 biolink:BiologicalProcess Mo-molybdopterin cofactor metabolic process The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. go-plus.json Moco metabolic process|Mo-molybdopterin cofactor metabolism|Moco metabolism http://purl.obolibrary.org/obo/GO_0019720 CHEBI:47979 biolink:ChemicalSubstance N-acetyl-alpha-muramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47979 chebi_ph7_3 GO:0019721 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019721 CHEBI:33340 biolink:ChemicalSubstance zinc group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33340 CHEBI:47960 biolink:ChemicalSubstance (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47960 CHEBI:47961 biolink:ChemicalSubstance (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_47961 chebi_ph7_3 CHEBI:47962 biolink:ChemicalSubstance aldehydo-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47962 CHEBI:47964 biolink:ChemicalSubstance aurone go-plus.json http://purl.obolibrary.org/obo/CHEBI_47964 chebi_ph7_3 CHEBI:23997 biolink:ChemicalSubstance ethyl 3-hydroxyhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23997 chebi_ph7_3 CHEBI:47965 biolink:ChemicalSubstance N-acetylmuramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47965 CHEBI:47967 biolink:ChemicalSubstance N-acetyl-beta-muramic acid 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47967 CHEBI:33317 biolink:ChemicalSubstance boron group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33317 CHEBI:33318 biolink:ChemicalSubstance main group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33318 PATO:0002226 biolink:OntologyClass subcylindrical A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical. go-plus.json http://purl.obolibrary.org/obo/PATO_0002226 CHEBI:23990 biolink:ChemicalSubstance ethyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_23990 chebi_ph7_3 UBERON:0004341 biolink:AnatomicalEntity primitive streak The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP] go-plus.json primitive streak - blastopore - germ ring http://purl.obolibrary.org/obo/UBERON_0004341 UBERON:0004340 biolink:AnatomicalEntity allantois A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]. go-plus.json allantoic bud http://purl.obolibrary.org/obo/UBERON_0004340 CHEBI:47968 biolink:ChemicalSubstance N-acetylmuramic acid 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47968 UBERON:0004347 biolink:AnatomicalEntity limb bud An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. go-plus.json limbbud|gemmae membrorum|limb buds http://purl.obolibrary.org/obo/UBERON_0004347 UBERON:0004348 biolink:AnatomicalEntity optic eminence The embryonic structure that gives rise to the corneal ectoderm go-plus.json http://purl.obolibrary.org/obo/UBERON_0004348 UBERON:0004345 biolink:AnatomicalEntity trophectoderm outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition go-plus.json http://purl.obolibrary.org/obo/UBERON_0004345 CHEBI:47950 biolink:ChemicalSubstance keto-D-fructuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47950 CHEBI:47951 biolink:ChemicalSubstance primary fluorescent chlorophyll catabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_47951 CHEBI:47952 biolink:ChemicalSubstance D-glucopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47952 CHEBI:47954 biolink:ChemicalSubstance beta-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47954 CHEBI:47955 biolink:ChemicalSubstance (2R)-phycocyanobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_47955 CHEBI:47956 biolink:ChemicalSubstance thiocarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_47956 CHEBI:33327 biolink:ChemicalSubstance silicon oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33327 CHEBI:33328 biolink:ChemicalSubstance silicon oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33328 GO:0019708 biolink:BiologicalProcess peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins. RESID:AA0309 go-plus.json peptidyl-glycine cholesteryl ester formation from peptidyl-glycine|peptidyl-glycine cholesteryl ester anabolism from peptidyl-glycine|peptidyl-glycine cholesteryl ester synthesis from peptidyl-glycine http://purl.obolibrary.org/obo/GO_0019708 GO:0019709 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase. RESID:AA0310 go-plus.json iron incorporation into iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide http://purl.obolibrary.org/obo/GO_0019709 GO:0019706 biolink:MolecularActivity protein-cysteine S-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]. RHEA:36683|EC:2.3.1.225|Reactome:R-HSA-5682084|Reactome:R-HSA-9647982|Reactome:R-HSA-9021072 go-plus.json protein-cysteine S-palmitoleyltransferase activity http://purl.obolibrary.org/obo/GO_0019706 GO:0019707 biolink:MolecularActivity protein-cysteine S-acyltransferase activity Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule. RHEA:63372 go-plus.json http://purl.obolibrary.org/obo/GO_0019707 NCBITaxon:272561 biolink:OrganismalEntity Chlamydia trachomatis D/UW-3/CX go-plus.json Chlamydia trachomatis strain D/UW-3/CX|Chlamydia trachomatis str. D/UW-3/CX http://purl.obolibrary.org/obo/NCBITaxon_272561 GO:0019704 biolink:BiologicalProcess peptidyl-L-cysteine S-myristoylation The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine. RESID:AA0307 go-plus.json peptidyl-S-myristoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine biosynthetic process from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0019704 GO:0019705 biolink:MolecularActivity protein-cysteine S-myristoyltransferase activity Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein]. RHEA:59736 go-plus.json http://purl.obolibrary.org/obo/GO_0019705 GO:0019702 biolink:MolecularActivity protein-arginine N5-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine. RHEA:48116|EC:2.1.1.322 go-plus.json protein-arginine delta-N-methyltransferase activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)|type IV PRMT activity|type IV protein arginine methyltransferase activity http://purl.obolibrary.org/obo/GO_0019702 GO:0019703 biolink:BiologicalProcess coenzyme A-peptidyl-cysteine covalent linking The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide. RESID:AA0306 go-plus.json http://purl.obolibrary.org/obo/GO_0019703 GO:0019700 biolink:BiologicalProcess organic phosphonate catabolic process The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. go-plus.json phosphonate catabolism|phosphonate degradation|phosphonate breakdown|organophosphonate catabolic process http://purl.obolibrary.org/obo/GO_0019700 GO:0019701 biolink:BiologicalProcess peptidyl-arginine N5-methylation The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine. RESID:AA0305 go-plus.json peptidyl-arginine delta-N-methylation http://purl.obolibrary.org/obo/GO_0019701 CHEBI:47957 biolink:ChemicalSubstance (3E)-phycocyanobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_47957 UBERON:0004339 biolink:AnatomicalEntity vault of skull Upper part of skull, consisting of parietals, frontals, post-parietals, and in some species the squamosal and a portion of the alisphenoid go-plus.json skull roof|calva|skullcap|skull vault|calvaria|cranial vault|calvarium http://purl.obolibrary.org/obo/UBERON_0004339 CHEBI:47958 biolink:ChemicalSubstance nicotinic acetylcholine receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_47958 CHEBI:47959 biolink:ChemicalSubstance 5-hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47959 CHEBI:47940 biolink:ChemicalSubstance 4,6-dioxohept-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47940 CHEBI:47941 biolink:ChemicalSubstance 4,6-dioxohept-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47941 chebi_ph7_3 CHEBI:47942 biolink:ChemicalSubstance pantetheine 4'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_47942 chebi_ph7_3 CHEBI:23976 biolink:ChemicalSubstance ethanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23976 CHEBI:47947 biolink:ChemicalSubstance keto-D-tagatose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47947 CHEBI:23982 biolink:ChemicalSubstance ethanols go-plus.json http://purl.obolibrary.org/obo/CHEBI_23982 RO:0002180 biolink:OntologyClass has component w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. RO:0002180 go-plus.json http://purl.obolibrary.org/obo/RO_0002180 CHEBI:23981 biolink:ChemicalSubstance ethanolamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_23981 CHEBI:47931 biolink:ChemicalSubstance beta-D-glucosyl-(1->4)-D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47931 chebi_ph7_3 CHEBI:47932 biolink:ChemicalSubstance D-glucosyl-(1->4)-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47932 CHEBI:47933 biolink:ChemicalSubstance D-glucopyranosyl-(1->4)-D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47933 chebi_ph7_3 CHEBI:33305 biolink:ChemicalSubstance tellurium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33305 CHEBI:33306 biolink:ChemicalSubstance carbon group element atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33306 CHEBI:33307 biolink:ChemicalSubstance thiocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33307 CHEBI:33308 biolink:ChemicalSubstance carboxylic ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_33308 chebi_ph7_3 CHEBI:33300 biolink:ChemicalSubstance pnictogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33300 CHEBI:33301 biolink:ChemicalSubstance bismuth atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33301 chebi_ph7_3 CHEBI:33302 biolink:ChemicalSubstance pnictogen molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33302 CHEBI:33303 biolink:ChemicalSubstance chalcogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33303 CHEBI:33304 biolink:ChemicalSubstance chalcogen molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33304 GO:0030259 biolink:BiologicalProcess lipid glycosylation Covalent attachment of a glycosyl residue to a lipid molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0030259 GO:0030257 biolink:CellularComponent type III protein secretion system complex A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase. go-plus.json TTSS complex|T3SS complex http://purl.obolibrary.org/obo/GO_0030257 GO:0030258 biolink:BiologicalProcess lipid modification The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0030258 RO:0002297 biolink:OntologyClass results in formation of RO:0002297 go-plus.json http://purl.obolibrary.org/obo/RO_0002297 GO:0005299 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005299 RO:0002298 biolink:OntologyClass results in morphogenesis of The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. RO:0002298 go-plus.json http://purl.obolibrary.org/obo/RO_0002298 RO:0002299 biolink:OntologyClass results in maturation of The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. RO:0002299 go-plus.json http://purl.obolibrary.org/obo/RO_0002299 GO:0005297 biolink:MolecularActivity proline:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in). go-plus.json hydrogen/proline transporter http://purl.obolibrary.org/obo/GO_0005297 GO:0005298 biolink:MolecularActivity proline:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in). RHEA:28967|Reactome:R-HSA-444100 go-plus.json sodium/proline symporter activity http://purl.obolibrary.org/obo/GO_0005298 GO:0005295 biolink:MolecularActivity neutral amino acid:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in). go-plus.json neutral amino acid-sodium cotransporter|sodium/neutral amino acid transporter http://purl.obolibrary.org/obo/GO_0005295 FAO:0001001 biolink:OntologyClass hypha A long, branching filamentous structure formed by a vegetatively growing fungus. go-plus.json http://purl.obolibrary.org/obo/FAO_0001001 GO:0005296 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005296 RO:0002295 biolink:OntologyClass results in developmental progression of p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). RO:0002295 go-plus.json http://purl.obolibrary.org/obo/RO_0002295 GO:0005293 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005293 RO:0002296 biolink:OntologyClass results in development of p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. RO:0002296 go-plus.json http://purl.obolibrary.org/obo/RO_0002296 GO:0005294 biolink:MolecularActivity neutral L-amino acid secondary active transmembrane transporter activity Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json neutral L-amino acid porter activity http://purl.obolibrary.org/obo/GO_0005294 GO:0030255 biolink:BiologicalProcess protein secretion by the type IV secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system. go-plus.json protein secretion by the type IV protein secretion system|protein secretion by the T4SS|type IV protein secretion system http://purl.obolibrary.org/obo/GO_0030255 GO:0030256 biolink:CellularComponent type I protein secretion system complex A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space. go-plus.json ABC translocator complex http://purl.obolibrary.org/obo/GO_0030256 GO:0030253 biolink:BiologicalProcess protein secretion by the type I secretion system The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. go-plus.json type I protein secretion system|protein secretion by the TOSS|protein secretion by the type I protein secretion system http://purl.obolibrary.org/obo/GO_0030253 GO:0030254 biolink:BiologicalProcess protein secretion by the type III secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. go-plus.json protein secretion by the TTSS|protein secretion by the T3SS|type III protein secretion system|protein secretion by the T3S|protein secretion by the type III protein secretion system http://purl.obolibrary.org/obo/GO_0030254 GO:0030251 biolink:MolecularActivity guanylate cyclase inhibitor activity Stops, prevents or reduces the activity of guanylate cyclase. go-plus.json http://purl.obolibrary.org/obo/GO_0030251 GO:0030252 biolink:BiologicalProcess growth hormone secretion The regulated release of growth hormone from secretory granules into the blood. go-plus.json somatotropin secretion http://purl.obolibrary.org/obo/GO_0030252 GO:0030250 biolink:MolecularActivity guanylate cyclase activator activity Binds to and increases the activity of guanylate cyclase. go-plus.json guanylin http://purl.obolibrary.org/obo/GO_0030250 GO:0030248 biolink:MolecularActivity cellulose binding Binding to cellulose. go-plus.json http://purl.obolibrary.org/obo/GO_0030248 GO:0030249 biolink:MolecularActivity guanylate cyclase regulator activity Modulates the activity of guanylate cyclase. go-plus.json http://purl.obolibrary.org/obo/GO_0030249 GO:0030246 biolink:MolecularActivity carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. go-plus.json selectin|sugar binding http://purl.obolibrary.org/obo/GO_0030246 goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_flybase_ribbon|goslim_chembl GO:0030247 biolink:MolecularActivity polysaccharide binding Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json polysaccharide assembly with MHC class II protein complex http://purl.obolibrary.org/obo/GO_0030247 RO:0002286 biolink:OntologyClass developmentally succeeded by Inverse of developmentally preceded by RO:0002286 go-plus.json http://purl.obolibrary.org/obo/RO_0002286 RO:0002285 biolink:OntologyClass RO:0002285 go-plus.json http://purl.obolibrary.org/obo/RO_0002285 GO:0030244 biolink:BiologicalProcess cellulose biosynthetic process The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. MetaCyc:PWY-1001 go-plus.json cellulose biosynthesis|cellulose anabolism|cellulose synthesis|cellulose formation http://purl.obolibrary.org/obo/GO_0030244 GO:0030245 biolink:BiologicalProcess cellulose catabolic process The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. go-plus.json cellulose degradation|cellulose breakdown|cellulose catabolism http://purl.obolibrary.org/obo/GO_0030245 GO:0030242 biolink:BiologicalProcess autophagy of peroxisome The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions. go-plus.json pexophagy|peroxisome degradation http://purl.obolibrary.org/obo/GO_0030242 GO:0030243 biolink:BiologicalProcess cellulose metabolic process The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. go-plus.json cellulose metabolism http://purl.obolibrary.org/obo/GO_0030243 GO:0030240 biolink:BiologicalProcess skeletal muscle thin filament assembly The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0030240 OBO:cl#lacks_part biolink:OntologyClass lacks_part lacks_part go-plus.json http://purl.obolibrary.org/obo/cl#lacks_part GO:0030241 biolink:BiologicalProcess skeletal muscle myosin thick filament assembly The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0030241 GO:0030239 biolink:BiologicalProcess myofibril assembly Formation of myofibrils, the repeating units of striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0030239 GO:0030237 biolink:BiologicalProcess female sex determination The specification of female sex of an individual organism. go-plus.json http://purl.obolibrary.org/obo/GO_0030237 GO:0030238 biolink:BiologicalProcess male sex determination The specification of male sex of an individual organism. go-plus.json http://purl.obolibrary.org/obo/GO_0030238 GO:0030235 biolink:MolecularActivity nitric-oxide synthase regulator activity Binds to and modulates the activity of nitric oxide synthase. go-plus.json nitric oxide synthase regulator activity http://purl.obolibrary.org/obo/GO_0030235 GO:0005279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005279 GO:0030236 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030236 GO:0005277 biolink:MolecularActivity acetylcholine transmembrane transporter activity Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. Reactome:R-HSA-264615 go-plus.json http://purl.obolibrary.org/obo/GO_0005277 GO:0005278 biolink:MolecularActivity acetylcholine:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out). go-plus.json acetylcholine:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0005278 GO:0005275 biolink:MolecularActivity amine transmembrane transporter activity Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. go-plus.json amine/polyamine transmembrane transporter activity|amino acid-polyamine transmembrane transporter activity|amine/amide/polyamine channel activity http://purl.obolibrary.org/obo/GO_0005275 GO:0005276 biolink:MolecularActivity obsolete vesicular amino acid:proton antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in). go-plus.json hydrogen:vesicular amine antiporter activity|vesicular hydrogen:amino acid antiporter activity http://purl.obolibrary.org/obo/GO_0005276 GO:0005274 biolink:MolecularActivity allantoin:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport. go-plus.json allantoin uptake transmembrane transporter activity|allantoin permease activity|allantoin/allantoate transporter http://purl.obolibrary.org/obo/GO_0005274 GO:0005272 biolink:MolecularActivity sodium channel activity Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-3295580|Reactome:R-HSA-2730664 go-plus.json http://purl.obolibrary.org/obo/GO_0005272 GO:0005280 biolink:MolecularActivity amino acid:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in). Reactome:R-HSA-8875623 go-plus.json cation/amino acid symporter|hydrogen:amino acid symporter activity http://purl.obolibrary.org/obo/GO_0005280 GO:0005281 biolink:MolecularActivity obsolete general amino acid permease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json general amino acid permease activity|general amino acid transporter http://purl.obolibrary.org/obo/GO_0005281 CHEBI:149591 biolink:ChemicalSubstance (dihydroxyphenyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_149591 GO:0030233 biolink:MolecularActivity deoxynucleotide transmembrane transporter activity Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0030233 GO:0030234 biolink:MolecularActivity enzyme regulator activity Binds to and modulates the activity of an enzyme. go-plus.json enzyme modulator|catalytic regulator activity|metalloenzyme regulator activity http://purl.obolibrary.org/obo/GO_0030234 goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_candida|goslim_yeast|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus GO:0030231 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030231 GO:0030232 biolink:CellularComponent insulin control element activator complex Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription. go-plus.json ICE activator complex http://purl.obolibrary.org/obo/GO_0030232 GO:0030230 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030230 GO:0030228 biolink:MolecularActivity lipoprotein particle receptor activity Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. go-plus.json lipoprotein receptor activity|plasma lipoprotein particle receptor activity http://purl.obolibrary.org/obo/GO_0030228 GO:0030229 biolink:MolecularActivity very-low-density lipoprotein particle receptor activity Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis. Wikipedia:VLDL_receptor go-plus.json apolipoprotein E receptor activity|very-low-density lipoprotein receptor activity|VLDL receptor http://purl.obolibrary.org/obo/GO_0030229 GO:0030226 biolink:MolecularActivity apolipoprotein receptor activity Combining with an apolipoprotein to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0030226 GO:0030227 biolink:MolecularActivity obsolete apolipoprotein E receptor activity OBSOLETE. Combining with apolipoprotein E to initiate a change in cell activity. go-plus.json apolipoprotein E receptor activity|ApoE receptor http://purl.obolibrary.org/obo/GO_0030227 GO:0030224 biolink:BiologicalProcess monocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte. go-plus.json monocyte cell differentiation http://purl.obolibrary.org/obo/GO_0030224 GO:0030225 biolink:BiologicalProcess macrophage differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. go-plus.json macrophage cell differentiation http://purl.obolibrary.org/obo/GO_0030225 RO:0002264 biolink:OntologyClass acts upstream of or within c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. RO:0002264 go-plus.json affects http://purl.obolibrary.org/obo/RO_0002264 GO:0005288 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005288 GO:0005289 biolink:MolecularActivity high-affinity arginine transmembrane transporter activity Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity arginine transmembrane transporter activity|high-affinity arginine transporter activity http://purl.obolibrary.org/obo/GO_0005289 GO:0005286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005286 GO:0005287 biolink:MolecularActivity high-affinity basic amino acid transmembrane transporter activity Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity basic amino acid transmembrane transporter activity|high-affinity basic amino acid transporter activity http://purl.obolibrary.org/obo/GO_0005287 GO:0005284 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005284 GO:0005285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005285 GO:0005282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005282 RO:0002263 biolink:OntologyClass acts upstream of c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. RO:0002263 go-plus.json http://purl.obolibrary.org/obo/RO_0002263 GO:0005283 biolink:MolecularActivity amino acid:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in). go-plus.json insulin-activated sodium/amino acid transporter activity|sodium:amino acid symporter activity|sodium/excitatory amino acid cotransporter activity|sodium/amino acid transporter activity|sodium/excitatory amino acid symporter activity|insulin-activated sodium:amino acid symporter activity|insulin-activated sodium:amino acid transporter activity|sodium:amino acid transporter activity|glutamate/aspartate:sodium symporter activity|isoleucine/valine:sodium symporter activity|threonine/serine:sodium symporter activity http://purl.obolibrary.org/obo/GO_0005283 GO:0005291 biolink:MolecularActivity high-affinity L-histidine transmembrane transporter activity Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity L-histidine transmembrane transporter activity|high affinity histidine permease activity http://purl.obolibrary.org/obo/GO_0005291 GO:0005292 biolink:MolecularActivity high-affinity lysine transmembrane transporter activity Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity lysine transmembrane transporter activity|high affinity lysine transporter activity http://purl.obolibrary.org/obo/GO_0005292 GO:0005290 biolink:MolecularActivity L-histidine transmembrane transporter activity Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. go-plus.json L-histidine transporter activity|histidine/arginine/lysine/ornithine porter activity http://purl.obolibrary.org/obo/GO_0005290 RO:0002258 biolink:OntologyClass developmentally_preceded_by Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p RO:0002258 go-plus.json http://purl.obolibrary.org/obo/RO_0002258 GO:0030222 biolink:BiologicalProcess eosinophil differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. go-plus.json eosinophil cell development|eosinophil cell differentiation|eosinophil development http://purl.obolibrary.org/obo/GO_0030222 GO:0030223 biolink:BiologicalProcess neutrophil differentiation The process in which a myeloid precursor cell acquires the specialized features of a neutrophil. go-plus.json neutrophil granulocyte differentiation|neutrophil cell differentiation|neutrophil granulocytopoiesis http://purl.obolibrary.org/obo/GO_0030223 GO:0030220 biolink:BiologicalProcess platelet formation The process in which platelets bud from long processes extended by megakaryocytes. go-plus.json platelet extrusion http://purl.obolibrary.org/obo/GO_0030220 GO:0030221 biolink:BiologicalProcess basophil differentiation The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell. go-plus.json basophil cell differentiation http://purl.obolibrary.org/obo/GO_0030221 GO:0030219 biolink:BiologicalProcess megakaryocyte differentiation The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. go-plus.json megakaryocyte cell differentiation http://purl.obolibrary.org/obo/GO_0030219 GO:0030217 biolink:BiologicalProcess T cell differentiation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. go-plus.json T-cell differentiation|T-lymphocyte differentiation|T cell development|T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0030217 GO:0030218 biolink:BiologicalProcess erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. Wikipedia:Erythropoiesis go-plus.json erythropoiesis|erythrocyte cell differentiation|red blood cell differentiation|RBC differentiation http://purl.obolibrary.org/obo/GO_0030218 GO:0030215 biolink:MolecularActivity semaphorin receptor binding Binding to a semaphorin receptor. go-plus.json plexin ligand|plexin binding|semaphorin receptor ligand http://purl.obolibrary.org/obo/GO_0030215 GO:0030216 biolink:BiologicalProcess keratinocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. go-plus.json keratinocyte cell differentiation http://purl.obolibrary.org/obo/GO_0030216 GO:0030213 biolink:BiologicalProcess hyaluronan biosynthetic process The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. go-plus.json hyaluronan anabolism|hyaluronan synthesis|hyaluronan formation|hyaluronan biosynthesis http://purl.obolibrary.org/obo/GO_0030213 GO:0030214 biolink:BiologicalProcess hyaluronan catabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. go-plus.json hyaluronan degradation|hyaluronan catabolism|hyaluronan breakdown http://purl.obolibrary.org/obo/GO_0030214 CHEBI:149561 biolink:ChemicalSubstance phosphatidylethanolamine O-33:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_149561 RO:0002254 biolink:OntologyClass has developmental contribution from x has developmental contribution from y iff x has some part z such that z develops from y RO:0002254 go-plus.json http://purl.obolibrary.org/obo/RO_0002254 CHEBI:149562 biolink:ChemicalSubstance phosphatidylethanolamine O-18:2_15:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_149562 GO:0005253 biolink:MolecularActivity anion channel activity Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient. Reactome:R-HSA-432034|Reactome:R-HSA-432036 go-plus.json non-selective anion channel activity http://purl.obolibrary.org/obo/GO_0005253 RO:0002255 biolink:OntologyClass developmentally contributes to inverse of has developmental contribution from RO:0002255 go-plus.json http://purl.obolibrary.org/obo/RO_0002255 GO:0005254 biolink:MolecularActivity chloride channel activity Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-975449|Reactome:R-HSA-975340|Reactome:R-HSA-427570|Reactome:R-HSA-2744349 go-plus.json http://purl.obolibrary.org/obo/GO_0005254 RO:0002256 biolink:OntologyClass t1 developmentally_induced_by t2 if there is a process of organ induction (GO:0001759) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor tissue type T to T', where T' develops_from T. RO:0002256 go-plus.json http://purl.obolibrary.org/obo/RO_0002256 GO:0005251 biolink:MolecularActivity delayed rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow. Reactome:R-HSA-5577050|Reactome:R-HSA-5577237 go-plus.json http://purl.obolibrary.org/obo/GO_0005251 GO:0005252 biolink:MolecularActivity open rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration. go-plus.json http://purl.obolibrary.org/obo/GO_0005252 GO:0005250 biolink:MolecularActivity A-type (transient outward) potassium channel activity Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential. Reactome:R-HSA-5577234 go-plus.json http://purl.obolibrary.org/obo/GO_0005250 GO:0019898 biolink:CellularComponent extrinsic component of membrane The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. Wikipedia:Peripheral_membrane_protein go-plus.json peripheral membrane protein|extrinsic to membrane http://purl.obolibrary.org/obo/GO_0019898 goslim_metagenomics GO:0019899 biolink:MolecularActivity enzyme binding Binding to an enzyme, a protein with catalytic activity. go-plus.json http://purl.obolibrary.org/obo/GO_0019899 goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast GO:0030211 biolink:BiologicalProcess heparin catabolic process The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. go-plus.json heparan sulfate catabolic process|heparin degradation|heparin breakdown|heparin catabolism http://purl.obolibrary.org/obo/GO_0030211 GO:0019896 biolink:BiologicalProcess axonal transport of mitochondrion The directed movement of mitochondria along microtubules in nerve cell axons. go-plus.json axon transport of mitochondria http://purl.obolibrary.org/obo/GO_0019896 goslim_synapse GO:0019897 biolink:CellularComponent extrinsic component of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json juxtamembrane|extrinsic to plasma membrane|peripheral plasma membrane protein http://purl.obolibrary.org/obo/GO_0019897 GO:0030212 biolink:BiologicalProcess hyaluronan metabolic process The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. go-plus.json hyaluronan metabolism http://purl.obolibrary.org/obo/GO_0030212 GO:0019894 biolink:MolecularActivity kinesin binding Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. go-plus.json http://purl.obolibrary.org/obo/GO_0019894 GO:0030210 biolink:BiologicalProcess heparin biosynthetic process The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. go-plus.json heparin anabolism|heparan sulfate biosynthetic process|heparin synthesis|heparin formation|heparin biosynthesis http://purl.obolibrary.org/obo/GO_0030210 GO:0019895 biolink:MolecularActivity obsolete kinesin-associated mitochondrial adaptor activity OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria. go-plus.json http://purl.obolibrary.org/obo/GO_0019895 GO:0019893 biolink:MolecularActivity obsolete DNA replication inhibitor OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA replication inhibitor http://purl.obolibrary.org/obo/GO_0019893 CHEBI:149558 biolink:ChemicalSubstance phosphatidylethanolamine O-33:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_149558 GO:0030208 biolink:BiologicalProcess dermatan sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. go-plus.json dermatan sulfate anabolism|chondroitin sulfate B biosynthetic process|chondroitin sulfate B biosynthesis|dermatan sulfate synthesis|dermatan sulfate formation|dermatan sulfate biosynthesis|dermatan sulphate biosynthesis|dermatan sulphate biosynthetic process http://purl.obolibrary.org/obo/GO_0030208 GO:0030209 biolink:BiologicalProcess dermatan sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. go-plus.json dermatan sulfate breakdown|dermatan sulphate catabolic process|chondroitin sulfate B catabolism|chondroitin sulfate B catabolic process|dermatan sulfate catabolism|dermatan sulphate catabolism|dermatan sulfate degradation http://purl.obolibrary.org/obo/GO_0030209 CHEBI:149559 biolink:ChemicalSubstance phosphatidylethanolamine O-18:1_15:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_149559 GO:0030206 biolink:BiologicalProcess chondroitin sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. go-plus.json chondroitin sulfate formation|chondroitin sulphate biosynthesis|chondroitin sulphate biosynthetic process|chondroitin sulfate biosynthesis|chondroitin sulfate anabolism|chondroitin sulfate synthesis http://purl.obolibrary.org/obo/GO_0030206 GO:0030207 biolink:BiologicalProcess chondroitin sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. go-plus.json chondroitin sulfate catabolism|chondroitin sulphate catabolism|chondroitin sulfate degradation|chondroitin sulfate breakdown|chondroitin sulphate catabolic process http://purl.obolibrary.org/obo/GO_0030207 GO:0030204 biolink:BiologicalProcess chondroitin sulfate metabolic process The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate. go-plus.json chondroitin sulphate metabolic process|chondroitin sulphate metabolism|chondroitin sulfate metabolism http://purl.obolibrary.org/obo/GO_0030204 GO:0030205 biolink:BiologicalProcess dermatan sulfate metabolic process The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues. go-plus.json dermatan sulphate metabolism|chondroitin sulfate B metabolic process|chondroitin sulfate B metabolism|dermatan sulphate metabolic process|dermatan sulfate metabolism http://purl.obolibrary.org/obo/GO_0030205 GO:0030202 biolink:BiologicalProcess heparin metabolic process The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. go-plus.json heparan sulfate metabolic process|heparin metabolism http://purl.obolibrary.org/obo/GO_0030202 GO:0030203 biolink:BiologicalProcess glycosaminoglycan metabolic process The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. Formerly known as mucopolysaccharides, they include hyaluronic acid and chondroitin, which provide lubrication in joints and form part of the matrix of cartilage. The three-dimensional structure of these molecules enables them to trap water, which forms a gel and gives glycosaminoglycans their elastic properties. go-plus.json glycosaminoglycan metabolism http://purl.obolibrary.org/obo/GO_0030203 GO:0005267 biolink:MolecularActivity potassium channel activity Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-1299297|Reactome:R-HSA-1299338|Reactome:R-HSA-1296037|Reactome:R-HSA-1296035|Reactome:R-HSA-1299318|Reactome:R-HSA-2534365|Reactome:R-HSA-1299304|Reactome:R-HSA-1296039|Reactome:R-HSA-1299359|Reactome:R-HSA-1296024|Reactome:R-HSA-5578910|Reactome:R-HSA-1296348 go-plus.json http://purl.obolibrary.org/obo/GO_0005267 GO:0005262 biolink:MolecularActivity calcium channel activity Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Reactome:R-HSA-139854|Reactome:R-HSA-139855|Reactome:R-HSA-3295579|Reactome:R-HSA-8949178|Reactome:R-HSA-8949145|Reactome:R-HSA-210420 go-plus.json http://purl.obolibrary.org/obo/GO_0005262 GO:0005260 biolink:MolecularActivity intracellularly ATP-gated chloride channel activity Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane. MetaCyc:3.6.3.49-RXN|EC:5.6.1.6 go-plus.json ATP phosphohydrolase (channel-conductance-controlling)|cystic-fibrosis membrane-conductance-regulating protein activity|ATP-binding and phosphorylation-dependent chloride channel activity|channel-conductance-controlling ATPase activity|cystic fibrosis transmembrane conductance regulator http://purl.obolibrary.org/obo/GO_0005260 CHEBI:149552 biolink:ChemicalSubstance emetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_149552 GO:0005261 biolink:MolecularActivity cation channel activity Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient. Reactome:R-HSA-1168376|Reactome:R-HSA-1296043|Reactome:R-HSA-169683|Reactome:R-HSA-2089943|Reactome:R-HSA-4420052|Reactome:R-HSA-426223 go-plus.json non-selective cation channel activity|cation diffusion facilitator activity http://purl.obolibrary.org/obo/GO_0005261 CHEBI:149553 biolink:ChemicalSubstance anticoronaviral agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_149553 GO:0030200 biolink:BiologicalProcess heparan sulfate proteoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. go-plus.json heparan sulfate proteoglycan degradation|heparan sulphate proteoglycan catabolic process|heparan sulfate proteoglycan catabolism|heparan sulfate proteoglycan breakdown|heparan sulphate proteoglycan catabolism|heparin proteoglycan catabolic process http://purl.obolibrary.org/obo/GO_0030200 GO:0030201 biolink:BiologicalProcess heparan sulfate proteoglycan metabolic process The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. go-plus.json heparan sulphate proteoglycan metabolic process|heparan sulfate proteoglycan metabolism|heparin proteoglycan metabolic process|heparan sulphate proteoglycan metabolism http://purl.obolibrary.org/obo/GO_0030201 GO:0005237 biolink:MolecularActivity inhibitory extracellular ligand-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels. go-plus.json http://purl.obolibrary.org/obo/GO_0005237 RO:0002231 biolink:OntologyClass has start location x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y RO:0002231 go-plus.json http://purl.obolibrary.org/obo/RO_0002231 GO:0005234 biolink:MolecularActivity extracellularly glutamate-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. go-plus.json extracellular-glutamate-gated ion channel activity http://purl.obolibrary.org/obo/GO_0005234 RO:0002232 biolink:OntologyClass has end location x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y RO:0002232 go-plus.json http://purl.obolibrary.org/obo/RO_0002232 CHEBI:149540 biolink:ChemicalSubstance 5-deoxy-D-ribofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_149540 chebi_ph7_3 RO:0002233 biolink:OntologyClass has input p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. RO:0002233 go-plus.json http://purl.obolibrary.org/obo/RO_0002233 GO:0005231 biolink:MolecularActivity excitatory extracellular ligand-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential. Reactome:R-HSA-399712|Reactome:R-HSA-432164|Reactome:R-HSA-399711|Reactome:R-HSA-420980|Reactome:R-HSA-438037 go-plus.json http://purl.obolibrary.org/obo/GO_0005231 RO:0002234 biolink:OntologyClass has output p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p. RO:0002234 go-plus.json http://purl.obolibrary.org/obo/RO_0002234 GO:0005232 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005232 CHEBI:149543 biolink:ChemicalSubstance L-altrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_149543 GO:0005230 biolink:MolecularActivity extracellular ligand-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0005230 RO:0002230 biolink:OntologyClass ends with x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. RO:0002230 go-plus.json http://purl.obolibrary.org/obo/RO_0002230 RO:0002229 biolink:OntologyClass ends Relation between occurrents, shares an end boundary with. RO:0002229 go-plus.json finishes http://purl.obolibrary.org/obo/RO_0002229 GO:0019878 biolink:BiologicalProcess lysine biosynthetic process via aminoadipic acid The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway. go-plus.json lysine biosynthesis, aminoadipic acid pathway|lysine biosynthetic process, aminoadipic acid pathway|lysine biosynthetic process, aminoadipic pathway|lysine biosynthesis, aminoadipic pathway|lysine formation via aminoadipic acid|lysine synthesis via aminoadipic acid|lysine anabolism via aminoadipic acid http://purl.obolibrary.org/obo/GO_0019878 RO:0002224 biolink:OntologyClass starts with x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. RO:0002224 go-plus.json http://purl.obolibrary.org/obo/RO_0002224 RO:0002225 biolink:OntologyClass RO:0002225 go-plus.json http://purl.obolibrary.org/obo/RO_0002225 GO:0019879 biolink:BiologicalProcess peptidyl-thyronine biosynthetic process from peptidyl-tyrosine The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine. go-plus.json peptidyl-thyronine formation from peptidyl-tyrosine|peptidyl-thyronine synthesis from peptidyl-tyrosine|peptidyl-thyronine anabolism from peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0019879 RO:0002226 biolink:OntologyClass RO:0002226 go-plus.json http://purl.obolibrary.org/obo/RO_0002226 GO:0019876 biolink:BiologicalProcess nylon catabolic process The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids. go-plus.json nylon degradation|nylon breakdown|nylon catabolism http://purl.obolibrary.org/obo/GO_0019876 GO:0019877 biolink:BiologicalProcess diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls. go-plus.json diaminopimelate anabolism|diaminopimelate synthesis|diaminopimelate formation|diaminopimelate biosynthesis http://purl.obolibrary.org/obo/GO_0019877 GO:0019874 biolink:MolecularActivity 6-aminohexanoate-cyclic-dimer hydrolase activity Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate. UM-BBD_reactionID:r1097|RHEA:16225|MetaCyc:3.5.2.12-RXN|KEGG_REACTION:R03448|EC:3.5.2.12 go-plus.json 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity http://purl.obolibrary.org/obo/GO_0019874 GO:0019875 biolink:MolecularActivity 6-aminohexanoate-dimer hydrolase activity Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate. MetaCyc:RXN-3962|UM-BBD_enzymeID:e0673|EC:3.5.1.46|RHEA:21364 go-plus.json 6-aminohexanoic acid oligomer hydrolase activity|N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0019875 GO:0019872 biolink:BiologicalProcess streptomycin biosynthetic process The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. go-plus.json streptomycin biosynthesis|streptomycin anabolism|streptomycin synthesis|streptomycin formation http://purl.obolibrary.org/obo/GO_0019872 GO:0019873 biolink:BiologicalProcess obsolete tellurium sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json tellurium sensitivity/resistance http://purl.obolibrary.org/obo/GO_0019873 GO:0019870 biolink:MolecularActivity potassium channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a potassium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0019870 GO:0019871 biolink:MolecularActivity sodium channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a sodium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0019871 GO:0005248 biolink:MolecularActivity voltage-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Reactome:R-HSA-5576895 go-plus.json voltage gated sodium channel activity|voltage-dependent sodium channel activity|voltage-gated sodium ion channel activity|voltage-sensitive sodium channel http://purl.obolibrary.org/obo/GO_0005248 GO:0005249 biolink:MolecularActivity voltage-gated potassium channel activity Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Reactome:R-HSA-1296127 go-plus.json voltage-dependent potassium channel activity|voltage-gated potassium ion channel activity|voltage gated potassium channel activity|voltage-sensitive potassium channel http://purl.obolibrary.org/obo/GO_0005249 GO:0005246 biolink:MolecularActivity calcium channel regulator activity Modulates the activity of a calcium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0005246 GO:0005247 biolink:MolecularActivity voltage-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Reactome:R-HSA-2744228 go-plus.json voltage gated chloride channel activity|voltage-dependent chloride channel activity http://purl.obolibrary.org/obo/GO_0005247 GO:0005244 biolink:MolecularActivity voltage-gated ion channel activity Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-dependent ion channel activity|voltage gated ion channel activity http://purl.obolibrary.org/obo/GO_0005244 RO:0002220 biolink:OntologyClass adjacent to x adjacent_to y iff: x and y share a boundary RO:0002220 go-plus.json http://purl.obolibrary.org/obo/RO_0002220 GO:0005245 biolink:MolecularActivity voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Reactome:R-HSA-9701141|Reactome:R-HSA-265645|Reactome:R-HSA-9701055|Reactome:R-HSA-5577213 go-plus.json voltage gated calcium channel activity|depolarization-activated voltage-gated calcium channel|depolarization-activated voltage gated calcium channel activity|voltage-sensitive calcium channel|dihydropyridine-sensitive calcium channel activity|voltage-dependent calcium channel activity|depolarization-activated calcium channel|voltage-gated calcium ion channel activity|depolarization-activated voltage-gated calcium channel activity http://purl.obolibrary.org/obo/GO_0005245 RO:0002221 biolink:OntologyClass inverse of surrounded_by RO:0002221 go-plus.json http://purl.obolibrary.org/obo/RO_0002221 GO:0005242 biolink:MolecularActivity inward rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. Reactome:R-HSA-5678418|Reactome:R-HSA-1296046|Reactome:R-HSA-1369017|Reactome:R-HSA-5678261|Reactome:R-HSA-1296045 go-plus.json Kir channel activity http://purl.obolibrary.org/obo/GO_0005242 RO:0002222 biolink:OntologyClass temporally related to RO:0002222 go-plus.json http://purl.obolibrary.org/obo/RO_0002222 RO:0002223 biolink:OntologyClass starts inverse of starts with RO:0002223 go-plus.json http://purl.obolibrary.org/obo/RO_0002223 GO:0005243 biolink:MolecularActivity gap junction channel activity A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes. Reactome:R-HSA-375340|Reactome:R-HSA-375330|Reactome:R-HSA-190681|Reactome:R-HSA-375342|Reactome:R-HSA-375339 go-plus.json innexin|connexin|intercellular channel|innexin channel activity http://purl.obolibrary.org/obo/GO_0005243 GO:0005240 biolink:MolecularActivity obsolete glycine receptor-associated protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json glycine receptor-associated protein http://purl.obolibrary.org/obo/GO_0005240 GO:0005241 biolink:MolecularActivity obsolete inward rectifier channel OBSOLETE. (Was not defined before being made obsolete). go-plus.json inward rectifier channel http://purl.obolibrary.org/obo/GO_0005241 RO:0002219 biolink:OntologyClass x surrounded_by y iff: x is adjacent to y and for every region r adjacent to x, r overlaps y RO:0002219 go-plus.json http://purl.obolibrary.org/obo/RO_0002219 RO:0002213 biolink:OntologyClass positively regulates Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2. RO:0002213 go-plus.json http://purl.obolibrary.org/obo/RO_0002213 GO:0019889 biolink:BiologicalProcess pteridine metabolic process The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group. go-plus.json pteridine metabolism http://purl.obolibrary.org/obo/GO_0019889 RO:0002215 biolink:OntologyClass capable of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. RO:0002215 go-plus.json http://purl.obolibrary.org/obo/RO_0002215 GO:0019887 biolink:MolecularActivity protein kinase regulator activity Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0019887 GO:0019888 biolink:MolecularActivity protein phosphatase regulator activity Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. Reactome:R-HSA-180038 go-plus.json protein phosphatase type 1 regulator activity|protein phosphatase type 4 regulator activity|protein phosphatase 2 regulator activity|protein phosphatase 3 regulator activity|protein phosphatase type 2A regulator activity|protein phosphatase type 2B regulator activity|calcineurin, intrinsic regulator activity|protein phosphatase type 2B, intrinsic regulator activity|protein phosphatase type 2A, intrinsic regulator activity|calcineurin regulator activity|protein phosphatase 3, intrinsic regulator activity|protein phosphatase 2, intrinsic regulator activity|protein phosphatase type 4, intrinsic regulator activity|protein phosphatase type 1, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0019888 RO:0002216 biolink:OntologyClass capable of part of c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. RO:0002216 go-plus.json http://purl.obolibrary.org/obo/RO_0002216 GO:0019885 biolink:BiologicalProcess antigen processing and presentation of endogenous peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. go-plus.json endogenous peptide antigen processing and presentation via MHC class I|antigen processing, endogenous antigen via major histocompatibility complex class I|antigen presentation, endogenous peptide antigen|antigen processing, endogenous antigen via MHC class I http://purl.obolibrary.org/obo/GO_0019885 GO:0019886 biolink:BiologicalProcess antigen processing and presentation of exogenous peptide antigen via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. go-plus.json antigen presentation, exogenous peptide antigen|exogenous peptide antigen processing and presentation via MHC class II|antigen presentation, exogenous antigen via MHC class II|antigen processing, exogenous antigen via major histocompatibility complex class II http://purl.obolibrary.org/obo/GO_0019886 GO:0019883 biolink:BiologicalProcess antigen processing and presentation of endogenous antigen The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex. go-plus.json antigen presentation, endogenous antigen http://purl.obolibrary.org/obo/GO_0019883 GO:0019884 biolink:BiologicalProcess antigen processing and presentation of exogenous antigen The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex. go-plus.json antigen presentation, exogenous antigen http://purl.obolibrary.org/obo/GO_0019884 GO:0019881 biolink:BiologicalProcess obsolete streptomycin susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json streptomycin susceptibility/resistance http://purl.obolibrary.org/obo/GO_0019881 GO:0019882 biolink:BiologicalProcess antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Wikipedia:Antigen_presentation go-plus.json antigen presentation|antigen processing http://purl.obolibrary.org/obo/GO_0019882 GO:0019880 biolink:BiologicalProcess obsolete bacteriocin susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json bacteriocin susceptibility/resistance http://purl.obolibrary.org/obo/GO_0019880 GO:0044820 biolink:BiologicalProcess mitotic telomere tethering at nuclear periphery The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0044820 RO:0002211 biolink:OntologyClass regulates process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2. RO:0002211 go-plus.json http://purl.obolibrary.org/obo/RO_0002211 RO:0002212 biolink:OntologyClass negatively regulates Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2. RO:0002212 go-plus.json http://purl.obolibrary.org/obo/RO_0002212 GO:0044827 biolink:BiologicalProcess modulation by host of viral genome replication A process in which a host organism modulates the frequency, rate or extent of viral genome replication. go-plus.json regulation by host of viral genome reproduction http://purl.obolibrary.org/obo/GO_0044827 GO:0044828 biolink:BiologicalProcess negative regulation by host of viral genome replication A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication. go-plus.json http://purl.obolibrary.org/obo/GO_0044828 RO:0002207 biolink:OntologyClass RO:0002207 go-plus.json http://purl.obolibrary.org/obo/RO_0002207 GO:0044825 biolink:MolecularActivity obsolete retroviral strand transfer activity OBSOLETE. Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction. go-plus.json strand transfer reaction http://purl.obolibrary.org/obo/GO_0044825 GO:0044826 biolink:BiologicalProcess viral genome integration into host DNA The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses. go-plus.json viral genome integration http://purl.obolibrary.org/obo/GO_0044826 GO:0044823 biolink:MolecularActivity retroviral integrase activity Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0044823 RO:0002202 biolink:OntologyClass develops from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y RO:0002202 go-plus.json http://purl.obolibrary.org/obo/RO_0002202 CHEBI:18515 biolink:ChemicalSubstance (1S,2S,4R)-limonene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18515 chebi_ph7_3 RO:0002203 biolink:OntologyClass develops into inverse of develops from RO:0002203 go-plus.json http://purl.obolibrary.org/obo/RO_0002203 GO:0044824 biolink:MolecularActivity retroviral 3' processing activity The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls. go-plus.json 3'-processing activity|3' processing reaction http://purl.obolibrary.org/obo/GO_0044824 GO:0044821 biolink:BiologicalProcess meiotic telomere tethering at nuclear periphery The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0044821 GO:0044822 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044822 GO:0044829 biolink:BiologicalProcess positive regulation by host of viral genome replication A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication. go-plus.json http://purl.obolibrary.org/obo/GO_0044829 PR:000018550 biolink:Protein fractalkine proteolytic cleavage product A fractalkine that has been processed by proteolytic cleavage. go-plus.json CX3CL1/ClvPrd http://purl.obolibrary.org/obo/PR_000018550 GO:0044830 biolink:BiologicalProcess modulation by host of viral RNA genome replication A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication. go-plus.json regulation by host of viral RNA genome replication http://purl.obolibrary.org/obo/GO_0044830 GO:0044831 biolink:BiologicalProcess modulation by virus of host cytokine production Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044831 GO:0044838 biolink:BiologicalProcess cell quiescence A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed. go-plus.json cellular quiescence|quiescence|cell cycle quiescence|G0 phase http://purl.obolibrary.org/obo/GO_0044838 gocheck_do_not_annotate GO:0044839 biolink:BiologicalProcess cell cycle G2/M phase transition The cell cycle process by which a cell in G2 phase commits to M phase. go-plus.json http://purl.obolibrary.org/obo/GO_0044839 GO:0044836 biolink:BiologicalProcess D-xylose fermentation The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0044836 GO:0044837 biolink:BiologicalProcess actomyosin contractile ring organization A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring. go-plus.json cytokinesis, actomyosin contractile ring organization http://purl.obolibrary.org/obo/GO_0044837 GO:0044834 biolink:CellularComponent retroviral intasome A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0044834 CHEBI:18504 biolink:ChemicalSubstance (1->3,1->4)-beta-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_18504 GO:0044835 biolink:BiologicalProcess hydrogen generation via nitrogenase The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0044835 GO:0044832 biolink:BiologicalProcess induction by virus of host cytokine production The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism. go-plus.json positive regulation by virus of host cytokine production http://purl.obolibrary.org/obo/GO_0044832 GO:0044833 biolink:BiologicalProcess modulation by virus of host protein transport Any viral process that modulates the frequency, rate or extent of protein transport in its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044833 GO:0044841 biolink:CellularComponent gut granule membrane The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0044841 GO:0044842 biolink:CellularComponent gut granule lumen The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0044842 GO:0044840 biolink:CellularComponent gut granule A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage. go-plus.json http://purl.obolibrary.org/obo/GO_0044840 GO:0044849 biolink:BiologicalProcess estrous cycle A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur. Wikipedia:Estrous_cycle go-plus.json http://purl.obolibrary.org/obo/GO_0044849 GO:0044847 biolink:BiologicalProcess iron acquisition from host The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell. go-plus.json iron acquisition by symbiont from host|heme acquisition|iron acquisition by symbiont from host heme|acquisition by organism of nutrients from host via siderophores|acquisition by symbiont of nutrients from host via siderophores|iron acquisition http://purl.obolibrary.org/obo/GO_0044847 GO:0044848 biolink:BiologicalProcess biological phase A distinct period or stage in a biological process or cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0044848 gocheck_do_not_manually_annotate GO:0044845 biolink:BiologicalProcess chain elongation of O-linked mannose residue Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0044845 GO:0044846 biolink:BiologicalProcess negative regulation by symbiont of indole acetic acid levels in host Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of IAA levels in host|negative regulation by symbiont of auxin levels in host http://purl.obolibrary.org/obo/GO_0044846 GO:0044843 biolink:BiologicalProcess cell cycle G1/S phase transition The cell cycle process by which a cell in G1 phase commits to S phase. go-plus.json http://purl.obolibrary.org/obo/GO_0044843 GO:0044844 biolink:BiologicalProcess meiotic interphase II The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge. go-plus.json http://purl.obolibrary.org/obo/GO_0044844 gocheck_do_not_annotate CHEBI:18533 biolink:ChemicalSubstance 5alpha-campestan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_18533 chebi_ph7_3 CHEBI:18534 biolink:ChemicalSubstance campest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_18534 chebi_ph7_3 PR:000018513 biolink:Protein proteinase-activated receptor 1 proteolytic cleavage product A proteinase-activated receptor 1 that has been processed by proteolytic cleavage. go-plus.json F2R/ClvPrd http://purl.obolibrary.org/obo/PR_000018513 GO:0044852 biolink:BiologicalProcess nonrepetitive DNA condensation The process in which chromatin structure of nonrepetitive regions of DNA is compacted prior to and during mitosis in eukaryotic cells. go-plus.json nonrepetitive DNA packaging http://purl.obolibrary.org/obo/GO_0044852 GO:0044853 biolink:CellularComponent plasma membrane raft A membrane raft that is part of the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044853 GO:0044850 biolink:BiologicalProcess menstrual cycle A type of ovulation cycle where the endometrium is shed if pregnancy does not occur. Wikipedia:Menstrual_cycle go-plus.json http://purl.obolibrary.org/obo/GO_0044850 GO:0044851 biolink:BiologicalProcess hair cycle phase The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0044851 gocheck_do_not_annotate GO:0044858 biolink:BiologicalProcess plasma membrane raft polarization The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity. go-plus.json plasma membrane polarization http://purl.obolibrary.org/obo/GO_0044858 GO:0044859 biolink:BiologicalProcess protein insertion into plasma membrane raft The process in which a protein is incorporated into a plasma membrane raft. go-plus.json http://purl.obolibrary.org/obo/GO_0044859 GO:0044856 biolink:BiologicalProcess plasma membrane raft localization Any process in which plasma membrane rafts are transported to, or maintained in, a specific location. go-plus.json http://purl.obolibrary.org/obo/GO_0044856 GO:0044857 biolink:BiologicalProcess plasma membrane raft organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts. go-plus.json http://purl.obolibrary.org/obo/GO_0044857 GO:0044854 biolink:BiologicalProcess plasma membrane raft assembly The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft. go-plus.json http://purl.obolibrary.org/obo/GO_0044854 GO:0044855 biolink:BiologicalProcess plasma membrane raft distribution The process that establishes the spatial arrangement of membrane rafts within a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044855 CHEBI:609827 biolink:ChemicalSubstance L-canavanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_609827 GO:0044863 biolink:BiologicalProcess modulation by virus of host cell division Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells. go-plus.json regulation by virus of host cell division http://purl.obolibrary.org/obo/GO_0044863 GO:0044864 biolink:BiologicalProcess positive regulation by virus of host cell division Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0044864 GO:0044861 biolink:BiologicalProcess protein transport into plasma membrane raft The directed movement of a protein into a plasma membrane raft. go-plus.json http://purl.obolibrary.org/obo/GO_0044861 GO:0044862 biolink:BiologicalProcess protein transport out of plasma membrane raft The directed movement of a protein out of a plasma membrane raft. go-plus.json http://purl.obolibrary.org/obo/GO_0044862 GO:0044860 biolink:BiologicalProcess protein localization to plasma membrane raft A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft. go-plus.json http://purl.obolibrary.org/obo/GO_0044860 GO:0030291 biolink:MolecularActivity protein serine/threonine kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0030291 GO:0030292 biolink:MolecularActivity protein tyrosine kinase inhibitor activity Stops, prevents or reduces the activity of a protein tyrosine kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0030292 GO:0044869 biolink:BiologicalProcess negative regulation by host of viral exo-alpha-sialidase activity The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0044869 GO:0030290 biolink:MolecularActivity sphingolipid activator protein activity Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase. Reactome:R-HSA-1605717 go-plus.json saposin http://purl.obolibrary.org/obo/GO_0030290 GO:0044867 biolink:BiologicalProcess modulation by host of viral catalytic activity The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected. go-plus.json http://purl.obolibrary.org/obo/GO_0044867 GO:0044868 biolink:BiologicalProcess modulation by host of viral molecular function A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected. go-plus.json http://purl.obolibrary.org/obo/GO_0044868 GO:0044865 biolink:BiologicalProcess negative regulation by virus of host cell division Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division. go-plus.json inhibition by virus of host cell division http://purl.obolibrary.org/obo/GO_0044865 GO:0044866 biolink:BiologicalProcess modulation by host of viral exo-alpha-sialidase activity The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0044866 GO:0030299 biolink:BiologicalProcess intestinal cholesterol absorption Uptake of cholesterol into the blood by absorption from the small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0030299 GO:0030297 biolink:MolecularActivity transmembrane receptor protein tyrosine kinase activator activity Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0030297 GO:0030298 biolink:MolecularActivity receptor signaling protein tyrosine kinase activator activity Binds to and increases the activity of a receptor signaling protein tyrosine kinase. go-plus.json receptor signalling protein tyrosine kinase activator activity http://purl.obolibrary.org/obo/GO_0030298 GO:0030295 biolink:MolecularActivity protein kinase activator activity Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0030295 GO:0030296 biolink:MolecularActivity protein tyrosine kinase activator activity Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0030296 GO:0030293 biolink:MolecularActivity transmembrane receptor protein tyrosine kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0030293 GO:0030294 biolink:MolecularActivity receptor signaling protein tyrosine kinase inhibitor activity Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase. go-plus.json receptor signalling protein tyrosine kinase inhibitor activity http://purl.obolibrary.org/obo/GO_0030294 GO:0044874 biolink:BiologicalProcess lipoprotein localization to outer membrane A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044874 GO:0044875 biolink:MolecularActivity gamma-glutamyl hercynylcysteine sulfoxide synthase activity Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 <=> gamma-glutamyl-hercynyl cysteine sulfoxide + H2O. RHEA:42672|EC:1.14.99.50 go-plus.json gamma-glutamyl hercynylcysteine S-oxide synthase|gamma-glutamyl hercynylcysteine sulfoxide synthase http://purl.obolibrary.org/obo/GO_0044875 GO:0044872 biolink:BiologicalProcess lipoprotein localization Any process in which a lipoprotein is transported to, or maintained in, a specific location. go-plus.json http://purl.obolibrary.org/obo/GO_0044872 GO:0044873 biolink:BiologicalProcess lipoprotein localization to membrane A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044873 GO:0044870 biolink:BiologicalProcess modulation by host of viral glycoprotein metabolic process A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0044870 GO:0044871 biolink:BiologicalProcess negative regulation by host of viral glycoprotein metabolic process A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0044871 GO:0030280 biolink:MolecularActivity structural constituent of skin epidermis The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure. go-plus.json structural constituent of epidermis http://purl.obolibrary.org/obo/GO_0030280 GO:0030281 biolink:MolecularActivity structural constituent of cutaneous appendage The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers. go-plus.json http://purl.obolibrary.org/obo/GO_0030281 GO:0044878 biolink:BiologicalProcess mitotic cytokinesis checkpoint signaling A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed. go-plus.json signaling pathway involved in mitotic cytokinesis checkpoint|signal transduction involved in mitotic cytokinesis checkpoint|cytokinesis after mitosis checkpoint|signalling pathway involved in mitotic cytokinesis checkpoint|defective cytokinesis checkpoint|signalling cascade involved in mitotic cytokinesis checkpoint|mitotic cytokinesis checkpoint http://purl.obolibrary.org/obo/GO_0044878 GO:0044879 biolink:BiologicalProcess mitotic morphogenesis checkpoint signaling A signaling process that contributes to a mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth. go-plus.json signalling cascade involved in septin checkpoint|septin checkpoint|signaling cascade involved in morphogenesis checkpoint|signaling cascade involved in septin checkpoint|signalling cascade involved in morphogenesis checkpoint|morphogenesis checkpoint|signalling pathway involved in septin checkpoint|signaling pathway involved in septin checkpoint|signaling pathway involved in morphogenesis checkpoint|signal transduction involved in morphogenesis checkpoint|signal transduction involved in septin checkpoint|signalling pathway involved in morphogenesis checkpoint http://purl.obolibrary.org/obo/GO_0044879 GO:0044876 biolink:MolecularActivity hercynylselenocysteine synthase Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 <=> 2 H2O + 2 hercynylselenocysteine. RHEA:42680|MetaCyc:RXN-15803 go-plus.json http://purl.obolibrary.org/obo/GO_0044876 GO:0044877 biolink:MolecularActivity protein-containing complex binding Binding to a macromolecular complex. go-plus.json protein complex binding|macromolecular complex binding http://purl.obolibrary.org/obo/GO_0044877 goslim_chembl GO:0030288 biolink:CellularComponent outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. Wikipedia:Periplasmic_space go-plus.json outer membrane-enclosed periplasmic space|outer membrane bounded periplasmic space http://purl.obolibrary.org/obo/GO_0030288 GO:0030289 biolink:CellularComponent protein phosphatase 4 complex A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0030289 GO:0030286 biolink:CellularComponent dynein complex Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0030286 GO:0030287 biolink:CellularComponent cell wall-bounded periplasmic space The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria. go-plus.json cell wall bounded periplasmic space|inner wall zone|cell wall-enclosed periplasmic space|IWZ http://purl.obolibrary.org/obo/GO_0030287 GO:0030284 biolink:MolecularActivity estrogen receptor activity Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function. go-plus.json http://purl.obolibrary.org/obo/GO_0030284 GO:0030285 biolink:CellularComponent integral component of synaptic vesicle membrane The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to synaptic vesicle membrane http://purl.obolibrary.org/obo/GO_0030285 goslim_synapse GO:0030282 biolink:BiologicalProcess bone mineralization The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. go-plus.json bone calcification http://purl.obolibrary.org/obo/GO_0030282 GO:0030283 biolink:MolecularActivity testosterone dehydrogenase [NAD(P)] activity Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+. MetaCyc:1.1.1.51-RXN|EC:1.1.1.51|Reactome:R-HSA-193064 go-plus.json 17beta-hydroxy steroid dehydrogenase|3beta-hydroxysteroid dehydrogenase|3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase|beta-hydroxy steroid dehydrogenase|3beta-hydroxy steroid dehydrogenase|3(or 17)beta-hydroxysteroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0030283 GO:0030279 biolink:BiologicalProcess negative regulation of ossification Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. go-plus.json negative regulation of bone formation|down-regulation of ossification|negative regulation of bone biosynthesis|downregulation of ossification|down regulation of ossification|inhibition of ossification http://purl.obolibrary.org/obo/GO_0030279 GO:0030270 biolink:MolecularActivity formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran. UM-BBD_reactionID:r0346|MetaCyc:2.3.1.101-RXN|EC:2.3.1.101|KEGG_REACTION:R03390|RHEA:18061 go-plus.json formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity|FTR|formylmethanofuran:tetrahydromethanopterin formyltransferase activity|formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity|N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity|formylmethanofuran-tetrahydromethanopterin formyltransferase activity http://purl.obolibrary.org/obo/GO_0030270 GO:0030277 biolink:BiologicalProcess maintenance of gastrointestinal epithelium Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents. go-plus.json http://purl.obolibrary.org/obo/GO_0030277 GO:0030278 biolink:BiologicalProcess regulation of ossification Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. go-plus.json regulation of bone biosynthesis|regulation of bone formation http://purl.obolibrary.org/obo/GO_0030278 GO:0030275 biolink:MolecularActivity LRR domain binding Binding to a LRR domain (leucine rich repeats) of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0030275 GO:0030276 biolink:MolecularActivity clathrin binding Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0030276 GO:0030273 biolink:MolecularActivity melanin-concentrating hormone receptor activity Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity. go-plus.json MCH receptor http://purl.obolibrary.org/obo/GO_0030273 GO:0030274 biolink:MolecularActivity LIM domain binding Binding to a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions. go-plus.json http://purl.obolibrary.org/obo/GO_0030274 GO:0030271 biolink:MolecularActivity obsolete chymase activity OBSOLETE. Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa. go-plus.json chymase activity|skeletal muscle (SK) protease activity|skin chymotryptic proteinase|SK protease activity|mast cell protease I activity|mast cell serine proteinase|skeletal muscle protease http://purl.obolibrary.org/obo/GO_0030271 GO:0030272 biolink:MolecularActivity 5-formyltetrahydrofolate cyclo-ligase activity Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate. Reactome:R-HSA-6801342|RHEA:10488|KEGG_REACTION:R02301|EC:6.3.3.2|MetaCyc:5-FORMYL-THF-CYCLO-LIGASE-RXN go-plus.json 5-Formyltetrahydrofolate cyclodehydrase activity|5-formyltetrahydrofolate cyclodehydrase|5-formyltetrahydrofolate cyclo-ligase (ADP-forming)|formyltetrahydrofolic cyclodehydrase activity|methenyl-THF synthetase activity|5,10-methenyltetrahydrofolate synthetase activity http://purl.obolibrary.org/obo/GO_0030272 GO:0030268 biolink:MolecularActivity methylenetetrahydromethanopterin dehydrogenase activity Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420. RHEA:16721|EC:1.5.98.1|UM-BBD_reactionID:r0348|MetaCyc:1.5.99.9-RXN|KEGG_REACTION:R04456 go-plus.json N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|5,10-methylenetetrahydromethanopterin dehydrogenase activity http://purl.obolibrary.org/obo/GO_0030268 GO:0030269 biolink:MolecularActivity tetrahydromethanopterin S-methyltransferase activity Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM. RHEA:53492|MetaCyc:2.1.1.86-RXN|EC:2.1.1.86|UM-BBD_reactionID:r0355|KEGG_REACTION:R04347 go-plus.json N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|tetrahydromethanopterin methyltransferase activity|5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity http://purl.obolibrary.org/obo/GO_0030269 NCBITaxon:1437010 biolink:OrganismalEntity Boreoeutheria go-plus.json Boreotheria http://purl.obolibrary.org/obo/NCBITaxon_1437010 GO:0030266 biolink:MolecularActivity quinate 3-dehydrogenase (NAD+) activity Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+. RHEA:22364|MetaCyc:QUINATE-5-DEHYDROGENASE-RXN|EC:1.1.1.282|EC:1.1.1.24|KEGG_REACTION:R01872 go-plus.json quinate:NAD(+) 3-oxidoreductase activity|quinate:NAD(+) 5-oxidoreductase activity|quinate:NAD 3-oxidoreductase activity|quinate:NAD 5-oxidoreductase activity|quinic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0030266 GO:0030267 biolink:MolecularActivity glyoxylate reductase (NADP+) activity Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+. MetaCyc:GLYOXYLATE-REDUCTASE-NADP+-RXN|Reactome:R-HSA-389826|EC:1.1.1.79|RHEA:10992|Wikipedia:Glyoxylate_reductase_(NADP+) go-plus.json NADPH-glyoxylate reductase activity|glyoxylate reductase (NADP+)|glycolate:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0030267 GO:0030264 biolink:BiologicalProcess nuclear fragmentation involved in apoptotic nuclear change The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA. go-plus.json nucleus fragmentation|nuclear fragmentation during apoptosis|apoptotic nuclear fragmentation http://purl.obolibrary.org/obo/GO_0030264 GO:0030265 biolink:BiologicalProcess phospholipase C-activating rhodopsin mediated signaling pathway The series of molecular signals generated as a consequence of a rhodopsin molecule being activated by a photon, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway|rhodopsin mediated G protein signaling, coupled to IP3 second messenger|PLC-activating rhodopsin mediated signaling pathway|rhodopsin mediated G protein signalling, coupled to IP3 second messenger|rhodopsin mediated G-protein signalling, coupled to IP3 second messenger|rhodopsin mediated G-protein signaling, coupled to IP3 second messenger http://purl.obolibrary.org/obo/GO_0030265 GO:0030262 biolink:BiologicalProcess apoptotic nuclear changes Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. go-plus.json apoptotic nuclear change http://purl.obolibrary.org/obo/GO_0030262 GO:0030263 biolink:BiologicalProcess apoptotic chromosome condensation The compaction of chromatin during apoptosis. Wikipedia:Pyknosis go-plus.json pyknosis http://purl.obolibrary.org/obo/GO_0030263 GO:0030260 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030260 GO:0030261 biolink:BiologicalProcess chromosome condensation The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. go-plus.json DNA condensation|eukaryotic chromosome condensation|nuclear chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 CHEBI:18481 biolink:ChemicalSubstance (-)-cis-sabinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18481 chebi_ph7_3 UBERON:0018664 biolink:AnatomicalEntity neck of bone element the neck region of a bone organ. go-plus.json bone neck|neck of bone http://purl.obolibrary.org/obo/UBERON_0018664 CHEBI:43445 biolink:ChemicalSubstance (+)-aristolochene go-plus.json http://purl.obolibrary.org/obo/CHEBI_43445 chebi_ph7_3 UBERON:0018667 biolink:AnatomicalEntity neck of scapula go-plus.json scapular neck|anatomical neck of scapula http://purl.obolibrary.org/obo/UBERON_0018667 UBERON:0004022 biolink:AnatomicalEntity germinal neuroepithelium The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells go-plus.json germinal neuroepithelial layer|germinal neuroepithelium|original neural tube http://purl.obolibrary.org/obo/UBERON_0004022 UBERON:0004023 biolink:AnatomicalEntity ganglionic eminence The transient proliferative population of neurons that expands exponentially during late prenatal development; it is a continuous germinal zone distinct from the ventricular zone that surrounds the brain ventricles[MP]. go-plus.json GE|fetal subventricular zone|SVZ|embryonic subventricular zone|embryonic SVZ|subventricular zone|subependymal layer|embryonic GE|embryonic/fetal subventricular zone http://purl.obolibrary.org/obo/UBERON_0004023 UBERON:0004021 biolink:AnatomicalEntity spongiotrophoblast layer The structure of the outer structural layer of the rodent placenta[MP]. go-plus.json spongiotrophoblast layer of placenta|spongiotrophoblast http://purl.obolibrary.org/obo/UBERON_0004021 UBERON:0004027 biolink:AnatomicalEntity chorionic plate That portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004027 CHEBI:43433 biolink:ChemicalSubstance L-alloisoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_43433 UBERON:0018657 biolink:AnatomicalEntity pupal case Any acellular shell or covering that surrounds the pupal form of an insect go-plus.json http://purl.obolibrary.org/obo/UBERON_0018657 UBERON:0004015 biolink:AnatomicalEntity embryonic-extraembryonic boundary The connection between the embryo proper and extraembryonic tissues go-plus.json http://purl.obolibrary.org/obo/UBERON_0004015 UBERON:0004016 biolink:AnatomicalEntity dermatome A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. go-plus.json epimere mesoderm|cutis plate|mesenchyma dermatomiale|dermatomal mesenchyme http://purl.obolibrary.org/obo/UBERON_0004016 UBERON:0018649 biolink:AnatomicalEntity cardiac muscle tissue of ventricle go-plus.json ventricular cardiac muscle tissue|ventricular muscle|ventricular heart muscle http://purl.obolibrary.org/obo/UBERON_0018649 UBERON:0004000 biolink:AnatomicalEntity tarsal gland acinus A sac-like structure comprising a sebaceous gland. go-plus.json Meibomian gland acinus|palpebral gland acinus|acinus of tarsal gland http://purl.obolibrary.org/obo/UBERON_0004000 UBERON:0004001 biolink:AnatomicalEntity olfactory bulb layer . go-plus.json cytoarchitectural part of olfactory bulb http://purl.obolibrary.org/obo/UBERON_0004001 CHEBI:43419 biolink:ChemicalSubstance isoursodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43419 NCBITaxon:6238 biolink:OrganismalEntity Caenorhabditis briggsae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6238 NCBITaxon:6239 biolink:OrganismalEntity Caenorhabditis elegans go-plus.json roundworm|Rhabditis elegans http://purl.obolibrary.org/obo/NCBITaxon_6239 NCBITaxon:6236 biolink:OrganismalEntity Rhabditida go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6236 NCBITaxon:6237 biolink:OrganismalEntity Caenorhabditis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6237 UBERON:0004066 biolink:AnatomicalEntity frontonasal prominence The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout. go-plus.json frontonasal mass|prominentia frontonasalis|forebrain prominence|embryonic frontonasal prominence|frontonasal process http://purl.obolibrary.org/obo/UBERON_0004066 UBERON:0004067 biolink:AnatomicalEntity lateral nasal prominence The lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo; it separates the olfactory pit from the developing eye and the ala of the nose/snout develops from it go-plus.json lateral nasal swelling|lateral nasal process|latero-nasal process|prominentia nasalis lateralis http://purl.obolibrary.org/obo/UBERON_0004067 UBERON:0004064 biolink:AnatomicalEntity neural tube basal plate The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons. go-plus.json ventral part of neural tube|spinal cord basal plate|basal plate of neural tube|motor part of neural tube|basal plate http://purl.obolibrary.org/obo/UBERON_0004064 UBERON:0004062 biolink:AnatomicalEntity neural tube marginal layer The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter go-plus.json brain marginal zone|neural tube marginal zone http://purl.obolibrary.org/obo/UBERON_0004062 UBERON:0004063 biolink:AnatomicalEntity spinal cord alar plate The region of the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses; the alar plate develops into the dorsal horn in the grey matter of the spinal cord go-plus.json alar column spinal cord|spinal cord alar column|spinal cord alar lamina http://purl.obolibrary.org/obo/UBERON_0004063 UBERON:0004060 biolink:AnatomicalEntity neural tube ventricular layer The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium go-plus.json neural tube ventricular zone|neural tube ventricular germinal zone|neural tube ependymal layer|neural tube ependymal zone|ependymal layer http://purl.obolibrary.org/obo/UBERON_0004060 UBERON:0004061 biolink:AnatomicalEntity neural tube mantle layer The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer. go-plus.json neural tube intermediate zone|future brain marginal layer http://purl.obolibrary.org/obo/UBERON_0004061 CHEBI:18435 biolink:ChemicalSubstance (+)-7-isojasmonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18435 NCBITaxon:6243 biolink:OrganismalEntity Rhabditidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6243 CHEBI:18430 biolink:ChemicalSubstance 3-hydroxy-16-methoxy-2,3-dihydrotabersonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18430 CHEBI:18431 biolink:ChemicalSubstance 7alpha,26-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18431 chebi_ph7_3 UBERON:0004068 biolink:AnatomicalEntity medial nasal prominence The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it go-plus.json medial nasal swelling|medial nasal process|prominentia nasalis medialis|nasomedial prominence|medial-nasal process http://purl.obolibrary.org/obo/UBERON_0004068 UBERON:0018692 biolink:AnatomicalEntity dorsal side of post-anal tail go-plus.json http://purl.obolibrary.org/obo/UBERON_0018692 UBERON:0018691 biolink:AnatomicalEntity ventral side of post-anal tail go-plus.json http://purl.obolibrary.org/obo/UBERON_0018691 CHEBI:5810 biolink:ChemicalSubstance hydroxymethylphosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_5810 UBERON:0004053 biolink:AnatomicalEntity external male genitalia The external masculine genital organs, including the penis and scrotum go-plus.json male external genitalia|external male genital organ|organa genitalia masculina externa http://purl.obolibrary.org/obo/UBERON_0004053 CHEBI:18429 biolink:ChemicalSubstance dehydrovomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18429 chebi_ph7_3 UBERON:0004054 biolink:AnatomicalEntity internal male genitalia The internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands go-plus.json organa genitalia masculina interna|male internal genitalia|internal male genital organ http://purl.obolibrary.org/obo/UBERON_0004054 CHEBI:18427 biolink:ChemicalSubstance 1D-1-O-methyl-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18427 chebi_ph7_3 CHEBI:18425 biolink:ChemicalSubstance 2-C-methyl-D-erythritol 2,4-cyclic diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18425 CHEBI:18426 biolink:ChemicalSubstance 1D-myo-inositol 1,2-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18426 CHEBI:18421 biolink:ChemicalSubstance superoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18421 chebi_ph7_3 CHEBI:18422 biolink:ChemicalSubstance sulfur dioxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18422 chebi_ph7_3 CHEBI:18420 biolink:ChemicalSubstance magnesium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18420 chebi_ph7_3 UBERON:0004058 biolink:AnatomicalEntity biliary ductule One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP] go-plus.json cholangiole|biliary ductule|terminal cholangiole|bile ductule|bile capillary|biliary ductule|ductuli biliferi http://purl.obolibrary.org/obo/UBERON_0004058 GO:0044805 biolink:BiologicalProcess late nucleophagy A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM. go-plus.json LN http://purl.obolibrary.org/obo/GO_0044805 GO:0044806 biolink:BiologicalProcess G-quadruplex DNA unwinding The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'. go-plus.json http://purl.obolibrary.org/obo/GO_0044806 GO:0044803 biolink:BiologicalProcess multi-organism membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044803 UBERON:0004042 biolink:AnatomicalEntity spleen secondary B follicle The nodules of antigen-activated, differentiating B cells, follicular dendritic cells, antigen-presenting T cells and macrophages in the spleen white pulp go-plus.json secondary spleen B cell follicle|splenic secondary B cell follicle http://purl.obolibrary.org/obo/UBERON_0004042 GO:0044804 biolink:BiologicalProcess autophagy of nucleus A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded. go-plus.json nucleophagy|nucleus degradation http://purl.obolibrary.org/obo/GO_0044804 UBERON:0004040 biolink:AnatomicalEntity cortical intermediate zone The region of the developing mammalian cortex that extends between the ventricular zone and the cortical plate (CP); normally, the IZ is a region of tangential migration of cells, and at midgestation, the lower part of the IZ develops into the subventricular zone go-plus.json cerebral cortex mantle layer|cortical mantle layer|IZ|cerebral cortex mantle zone http://purl.obolibrary.org/obo/UBERON_0004040 GO:0044801 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044801 GO:0044802 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044802 UBERON:0004041 biolink:AnatomicalEntity spleen primary B follicle The nodules of small undifferentiated B lymphocytes and follicular dendritic cells located in the spleen white pulp go-plus.json primary spleen B cell follicle http://purl.obolibrary.org/obo/UBERON_0004041 GO:0044800 biolink:BiologicalProcess multi-organism membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044800 GO:0044809 biolink:BiologicalProcess chemokine (C-C motif) ligand 17 production The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json thymus and activation regulated chemokine production|CCL17 production|TARC production http://purl.obolibrary.org/obo/GO_0044809 gocheck_do_not_annotate GO:0044807 biolink:BiologicalProcess macrophage migration inhibitory factor production The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json MIF production http://purl.obolibrary.org/obo/GO_0044807 gocheck_do_not_annotate CHEBI:18450 biolink:ChemicalSubstance (R)-mandelonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_18450 chebi_ph7_3 GO:0044808 biolink:BiologicalProcess oncostatin M production The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json Oncostatin M production|OSM production http://purl.obolibrary.org/obo/GO_0044808 gocheck_do_not_annotate UBERON:0018674 biolink:AnatomicalEntity heart vasculature An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart. go-plus.json cardiac vasculature http://purl.obolibrary.org/obo/UBERON_0018674 UBERON:0018673 biolink:AnatomicalEntity neck of fibula go-plus.json fibular neck|fibula neck http://purl.obolibrary.org/obo/UBERON_0018673 UBERON:0018679 biolink:AnatomicalEntity thoracic splanchnic nerve Thoracic splanchnic nerves are splanchnic nerves that arise from the sympathetic trunk in the thorax and travel inferiorly to provide sympathetic innervation to the abdomen. The nerves contain preganglionic sympathetic and general visceral afferent fibers. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018679 GO:0044816 biolink:CellularComponent Nsk1-Dlc1 complex A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation. go-plus.json http://purl.obolibrary.org/obo/GO_0044816 GO:0044817 biolink:BiologicalProcess hydrogen generation via biophotolysis The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae. go-plus.json hydrogen biosynthesis via biophotolysis http://purl.obolibrary.org/obo/GO_0044817 GO:0044814 biolink:BiologicalProcess glycolytic fermentation via PFL pathway The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli. go-plus.json http://purl.obolibrary.org/obo/GO_0044814 GO:0044815 biolink:CellularComponent DNA packaging complex A protein complex that plays a role in the process of DNA packaging. go-plus.json http://purl.obolibrary.org/obo/GO_0044815 GO:0044812 biolink:BiologicalProcess fermentative hydrogen production The fermentation of organic substances with a net release of hydrogen. Wikipedia:Fermentative_hydrogen_production go-plus.json carbohydrate fermentation http://purl.obolibrary.org/obo/GO_0044812 GO:0044813 biolink:BiologicalProcess glycolytic fermentation via PFOR pathway The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species. go-plus.json http://purl.obolibrary.org/obo/GO_0044813 GO:0044810 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044810 GO:0044811 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044811 NCBITaxon:6231 biolink:OrganismalEntity Nematoda go-plus.json Nemata|roundworms|nematodes|nematodes|nematode|roundworm http://purl.obolibrary.org/obo/NCBITaxon_6231 UBERON:0004035 biolink:AnatomicalEntity cortical subplate The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate go-plus.json subplate|subplate zone|SP|cerebral cortex subplate http://purl.obolibrary.org/obo/UBERON_0004035 GO:0044818 biolink:BiologicalProcess mitotic G2/M transition checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0044818 GO:0044819 biolink:BiologicalProcess mitotic G1/S transition checkpoint signaling A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle. go-plus.json mitotic G1/S transition checkpoint http://purl.obolibrary.org/obo/GO_0044819 GO:0005219 biolink:MolecularActivity ryanodine-sensitive calcium-release channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. Reactome:R-HSA-2855020 go-plus.json ryanodine receptor|caffeine-sensitive calcium-release channel http://purl.obolibrary.org/obo/GO_0005219 GO:0005217 biolink:MolecularActivity intracellular ligand-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0005217 GO:0005218 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005218 GO:0005215 biolink:MolecularActivity transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. EC:7.-.-.-|Reactome:R-HSA-178215|Reactome:R-HSA-168313 go-plus.json carrier http://purl.obolibrary.org/obo/GO_0005215 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_candida|goslim_agr|gocheck_do_not_annotate|goslim_plant|goslim_pir|goslim_metagenomics|goslim_aspergillus GO:0005216 biolink:MolecularActivity ion channel activity Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size). go-plus.json http://purl.obolibrary.org/obo/GO_0005216 GO:0005213 biolink:MolecularActivity structural constituent of egg chorion The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster. go-plus.json structural protein of chorion|structural constituent of chorion http://purl.obolibrary.org/obo/GO_0005213 GO:0005214 biolink:MolecularActivity structural constituent of chitin-based cuticle The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0005214 CHEBI:125678 biolink:ChemicalSubstance N-acetyldopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_125678 chebi_ph7_3 GO:0005211 biolink:MolecularActivity obsolete plasma glycoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json plasma glycoprotein http://purl.obolibrary.org/obo/GO_0005211 GO:0005212 biolink:MolecularActivity structural constituent of eye lens The action of a molecule that contributes to the structural integrity of the lens of an eye. go-plus.json http://purl.obolibrary.org/obo/GO_0005212 GO:0019858 biolink:BiologicalProcess cytosine metabolic process The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. go-plus.json cytosine metabolism http://purl.obolibrary.org/obo/GO_0019858 GO:0019859 biolink:BiologicalProcess thymine metabolic process The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. go-plus.json thymine metabolism http://purl.obolibrary.org/obo/GO_0019859 GO:0019856 biolink:BiologicalProcess pyrimidine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. go-plus.json pyrimidine base synthesis|pyrimidine base formation|pyrimidine base biosynthesis|pyrimidine base anabolism|pyrimidine base biosynthetic process http://purl.obolibrary.org/obo/GO_0019856 GO:0019857 biolink:BiologicalProcess 5-methylcytosine metabolic process The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA. go-plus.json 5-methylcytosine metabolism http://purl.obolibrary.org/obo/GO_0019857 GO:0019854 biolink:BiologicalProcess L-ascorbic acid catabolic process The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions. MetaCyc:PWY0-301 go-plus.json ascorbate catabolism|ascorbate catabolic process|L-ascorbic acid catabolism|L-ascorbic acid degradation|vitamin C catabolism|L-ascorbic acid breakdown|vitamin C catabolic process http://purl.obolibrary.org/obo/GO_0019854 GO:0019855 biolink:MolecularActivity calcium channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a calcium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0019855 GO:0019852 biolink:BiologicalProcess L-ascorbic acid metabolic process The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. go-plus.json ascorbate metabolic process|ascorbate metabolism|vitamin C metabolic process|L-ascorbic acid metabolism|vitamin C metabolism http://purl.obolibrary.org/obo/GO_0019852 GO:0019853 biolink:BiologicalProcess L-ascorbic acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions. MetaCyc:PWY-882 go-plus.json L-ascorbic acid anabolism|ascorbate biosynthetic process|ascorbate biosynthesis|L-ascorbic acid synthesis|L-ascorbic acid formation|L-ascorbic acid biosynthesis|vitamin C biosynthetic process|vitamin C biosynthesis http://purl.obolibrary.org/obo/GO_0019853 GO:0019850 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019850 GO:0019851 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019851 GO:0005228 biolink:MolecularActivity intracellular sodium activated potassium channel activity Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification. go-plus.json http://purl.obolibrary.org/obo/GO_0005228 GO:0005229 biolink:MolecularActivity intracellular calcium activated chloride channel activity Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Reactome:R-HSA-2684901|Reactome:R-HSA-2744242|Reactome:R-HSA-9659568|Reactome:R-HSA-2744361 go-plus.json http://purl.obolibrary.org/obo/GO_0005229 GO:0005226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005226 GO:0005227 biolink:MolecularActivity calcium activated cation channel activity Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient. go-plus.json polycystin|intracellular calcium-activated potassium channel http://purl.obolibrary.org/obo/GO_0005227 GO:0005224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005224 GO:0005225 biolink:MolecularActivity volume-sensitive anion channel activity Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell. Reactome:R-HSA-8941543 go-plus.json volume-regulated channel http://purl.obolibrary.org/obo/GO_0005225 GO:0005222 biolink:MolecularActivity intracellular cAMP-activated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts. go-plus.json hyperpolarization-activated cyclic nucleotide-gated channel activity|intracellular 3',5'-cAMP activated cation channel activity|intracellular adenosine 3',5'-cyclophosphate activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular cyclic AMP activated cation channel activity|intracellular 3',5' cAMP activated cation channel activity|HCN channel activity http://purl.obolibrary.org/obo/GO_0005222 GO:0005223 biolink:MolecularActivity intracellular cGMP-activated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts. go-plus.json intracellular cGMP activated cation channel activity http://purl.obolibrary.org/obo/GO_0005223 GO:0005220 biolink:MolecularActivity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts. go-plus.json inositol-1,4,5-trisphosphate receptor activity|IP3 receptor activity|InsP3 receptor http://purl.obolibrary.org/obo/GO_0005220 GO:0005221 biolink:MolecularActivity intracellular cyclic nucleotide activated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts. Reactome:R-HSA-2514867 go-plus.json http://purl.obolibrary.org/obo/GO_0005221 GO:0019869 biolink:MolecularActivity chloride channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a chloride channel. go-plus.json http://purl.obolibrary.org/obo/GO_0019869 GO:0019867 biolink:CellularComponent outer membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. go-plus.json http://purl.obolibrary.org/obo/GO_0019867 goslim_metagenomics GO:0019868 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019868 GO:0019865 biolink:MolecularActivity immunoglobulin binding Binding to an immunoglobulin. go-plus.json http://purl.obolibrary.org/obo/GO_0019865 GO:0019866 biolink:CellularComponent organelle inner membrane The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. go-plus.json http://purl.obolibrary.org/obo/GO_0019866 GO:0019863 biolink:MolecularActivity IgE binding Binding to an immunoglobulin of the IgE isotype. go-plus.json http://purl.obolibrary.org/obo/GO_0019863 GO:0019864 biolink:MolecularActivity IgG binding Binding to an immunoglobulin of an IgG isotype. go-plus.json http://purl.obolibrary.org/obo/GO_0019864 goslim_chembl GO:0019861 biolink:CellularComponent obsolete flagellum OBSOLETE. Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium. Wikipedia:Flagellum go-plus.json flagellum http://purl.obolibrary.org/obo/GO_0019861 GO:0019862 biolink:MolecularActivity IgA binding Binding to an immunoglobulin of an IgA isotype. go-plus.json http://purl.obolibrary.org/obo/GO_0019862 GO:0019860 biolink:BiologicalProcess uracil metabolic process The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. go-plus.json uracil metabolism http://purl.obolibrary.org/obo/GO_0019860 GO:0019838 biolink:MolecularActivity growth factor binding Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate. go-plus.json neurotrophin TRK receptor activity http://purl.obolibrary.org/obo/GO_0019838 goslim_chembl GO:0019839 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019839 GO:0019836 biolink:BiologicalProcess hemolysis by symbiont of host erythrocytes The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json regulation of cytolysis of host cells by symbiont|haemolysis in host|hemolysis by symbiont of host RBCs|hemolysis by symbiont of host red blood cells|hemolysin activity|pathogenesis http://purl.obolibrary.org/obo/GO_0019836 GO:0019837 biolink:BiologicalProcess obsolete herbicide susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json herbicide susceptibility/resistance http://purl.obolibrary.org/obo/GO_0019837 GO:0019834 biolink:MolecularActivity phospholipase A2 inhibitor activity Binds to and stops, prevents or reduces the activity of phospholipase A2. go-plus.json http://purl.obolibrary.org/obo/GO_0019834 GO:0019835 biolink:BiologicalProcess cytolysis The rupture of cell membranes and the loss of cytoplasm. Wikipedia:Cytolysis go-plus.json necrosis|autolysin activity|bacteriolytic toxin activity|bacteriocin activity|lysis|holin|lysin activity http://purl.obolibrary.org/obo/GO_0019835 goslim_chembl GO:0019832 biolink:BiologicalProcess obsolete mercuric sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json mercuric sensitivity/resistance http://purl.obolibrary.org/obo/GO_0019832 GO:0019833 biolink:MolecularActivity obsolete ice nucleation activity OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation. go-plus.json ice nucleation activity http://purl.obolibrary.org/obo/GO_0019833 GO:0019830 biolink:BiologicalProcess obsolete cadmium sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json cadmium sensitivity/resistance http://purl.obolibrary.org/obo/GO_0019830 GO:0019831 biolink:BiologicalProcess obsolete chromate sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json chromate sensitivity/resistance http://purl.obolibrary.org/obo/GO_0019831 GO:0005208 biolink:MolecularActivity obsolete amyloid protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json amyloid protein http://purl.obolibrary.org/obo/GO_0005208 GO:0005209 biolink:MolecularActivity obsolete plasma protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json plasma protein http://purl.obolibrary.org/obo/GO_0005209 GO:0005206 biolink:MolecularActivity obsolete heparin sulfate proteoglycan OBSOLETE. (Was not defined before being made obsolete). go-plus.json heparin sulfate proteoglycan|heparin sulphate proteoglycan http://purl.obolibrary.org/obo/GO_0005206 GO:0005207 biolink:MolecularActivity obsolete extracellular matrix glycoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json extracellular matrix glycoprotein http://purl.obolibrary.org/obo/GO_0005207 GO:0005204 biolink:MolecularActivity obsolete chondroitin sulfate proteoglycan OBSOLETE. (Was not defined before being made obsolete). go-plus.json chondroitin sulphate proteoglycan|chondroitin sulfate proteoglycan http://purl.obolibrary.org/obo/GO_0005204 GO:0005205 biolink:MolecularActivity obsolete chondroitin sulfate/dermatan sulfate proteoglycan OBSOLETE. (Was not defined before being made obsolete). go-plus.json chondroitin sulfate/dermatan sulfate proteoglycan|chondroitin sulphate/dermatan sulphate proteoglycan http://purl.obolibrary.org/obo/GO_0005205 GO:0005202 biolink:MolecularActivity obsolete collagen OBSOLETE. (Was not defined before being made obsolete). go-plus.json collagen http://purl.obolibrary.org/obo/GO_0005202 GO:0005203 biolink:MolecularActivity obsolete proteoglycan OBSOLETE. (Was not defined before being made obsolete). go-plus.json proteoglycan http://purl.obolibrary.org/obo/GO_0005203 GO:0005200 biolink:MolecularActivity structural constituent of cytoskeleton The action of a molecule that contributes to the structural integrity of a cytoskeletal structure. go-plus.json http://purl.obolibrary.org/obo/GO_0005200 goslim_drosophila GO:0005201 biolink:MolecularActivity extracellular matrix structural constituent The action of a molecule that contributes to the structural integrity of the extracellular matrix. go-plus.json extracellular matrix glycoprotein|core matrisome|core extracellular matrix http://purl.obolibrary.org/obo/GO_0005201 goslim_drosophila GO:0019849 biolink:MolecularActivity obsolete cytotoxin activity OBSOLETE. Acts as to cause injury to other living cells. go-plus.json cytotoxin activity http://purl.obolibrary.org/obo/GO_0019849 GO:0019847 biolink:MolecularActivity obsolete neurotoxin activity OBSOLETE. Acts to inhibit neural function in another living organism. go-plus.json neurotoxin activity http://purl.obolibrary.org/obo/GO_0019847 GO:0019848 biolink:MolecularActivity obsolete conotoxin activity OBSOLETE. Acts to inhibit neural function in another organism by inhibiting voltage-gated calcium ion channels and neurotransmitter release. This function is thought to be specific to the venom of two marine snail species. go-plus.json conotoxin activity http://purl.obolibrary.org/obo/GO_0019848 GO:0019845 biolink:MolecularActivity obsolete exotoxin activity OBSOLETE. The function of a toxin formed by a microorganism and secreted into the surrounding medium. go-plus.json exotoxin activity http://purl.obolibrary.org/obo/GO_0019845 GO:0019846 biolink:MolecularActivity obsolete enterotoxin activity OBSOLETE. Acts as to cause injury to the intestinal mucosa of other living organisms. go-plus.json enterotoxin activity http://purl.obolibrary.org/obo/GO_0019846 GO:0019843 biolink:MolecularActivity rRNA binding Binding to a ribosomal RNA. go-plus.json base pairing with rRNA http://purl.obolibrary.org/obo/GO_0019843 goslim_generic|goslim_chembl|goslim_yeast GO:0019844 biolink:MolecularActivity obsolete endotoxin activity OBSOLETE. The function of any microbial toxin that cannot be easily separated from the structure of the cell. go-plus.json endotoxin activity http://purl.obolibrary.org/obo/GO_0019844 GO:0019841 biolink:MolecularActivity retinol binding Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation. go-plus.json vitamin A1 alcohol binding|vitamin A1 binding http://purl.obolibrary.org/obo/GO_0019841 GO:0019842 biolink:MolecularActivity vitamin binding Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0019842 goslim_pir|goslim_metagenomics GO:0019840 biolink:MolecularActivity isoprenoid binding Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. go-plus.json http://purl.obolibrary.org/obo/GO_0019840 goslim_pir GO:0019818 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019818 GO:0019819 biolink:CellularComponent P1 peroxisome A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms. go-plus.json peroxisome vesicle http://purl.obolibrary.org/obo/GO_0019819 GO:0019816 biolink:CellularComponent obsolete B cell receptor accessory molecule complex OBSOLETE. (Was not defined before being made obsolete). go-plus.json B cell receptor accessory molecule complex http://purl.obolibrary.org/obo/GO_0019816 GO:0019817 biolink:BiologicalProcess vesicle fusion with peroxisome The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome. go-plus.json http://purl.obolibrary.org/obo/GO_0019817 GO:0019814 biolink:CellularComponent immunoglobulin complex A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json antibody http://purl.obolibrary.org/obo/GO_0019814 goslim_pir GO:0019815 biolink:CellularComponent B cell receptor complex An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json immunoglobulin complex, membrane bound|B lymphocyte receptor complex|B cell receptor accessory molecule complex|B-lymphocyte receptor complex|BCR complex|B-cell receptor complex|antibody http://purl.obolibrary.org/obo/GO_0019815 GO:0019812 biolink:CellularComponent type I site-specific deoxyribonuclease complex A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell. go-plus.json type I restriction enzyme complex http://purl.obolibrary.org/obo/GO_0019812 GO:0019813 biolink:CellularComponent type III site-specific deoxyribonuclease complex A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell. go-plus.json type III restriction enzyme complex http://purl.obolibrary.org/obo/GO_0019813 GO:0019810 biolink:MolecularActivity putrescine binding Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. go-plus.json http://purl.obolibrary.org/obo/GO_0019810 GO:0019811 biolink:MolecularActivity cocaine binding Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0019811 CHEBI:43474 biolink:ChemicalSubstance hydrogenphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_43474 chebi_ph7_3 GO:0019829 biolink:MolecularActivity ATPase-coupled cation transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in). Reactome:R-HSA-5251989|Reactome:R-HSA-5692480 go-plus.json ATP-dependent cation transmembrane transporter activity|plasma membrane cation-transporting ATPase|cation ABC transporter|cation-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0019829 GO:0019827 biolink:BiologicalProcess stem cell population maintenance The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types. go-plus.json maintenance of pluripotency http://purl.obolibrary.org/obo/GO_0019827 GO:0019828 biolink:MolecularActivity aspartic-type endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process. go-plus.json aspartic protease inhibitor activity http://purl.obolibrary.org/obo/GO_0019828 GO:0019825 biolink:MolecularActivity oxygen binding Binding to oxygen (O2). go-plus.json cytochrome P450|cytochrome P450 activity http://purl.obolibrary.org/obo/GO_0019825 goslim_plant|goslim_pir GO:0019826 biolink:MolecularActivity oxygen sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2). go-plus.json http://purl.obolibrary.org/obo/GO_0019826 GO:0019823 biolink:CellularComponent P5 peroxisome A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content. go-plus.json peroxisome vesicle http://purl.obolibrary.org/obo/GO_0019823 GO:0019824 biolink:CellularComponent P6 peroxisome A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes. go-plus.json peroxisome vesicle http://purl.obolibrary.org/obo/GO_0019824 GO:0019821 biolink:CellularComponent P3 peroxisome A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content. go-plus.json peroxisome vesicle http://purl.obolibrary.org/obo/GO_0019821 GO:0019822 biolink:CellularComponent P4 peroxisome A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content. go-plus.json peroxisome vesicle http://purl.obolibrary.org/obo/GO_0019822 GO:0019820 biolink:CellularComponent P2 peroxisome A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed. go-plus.json peroxisome vesicle http://purl.obolibrary.org/obo/GO_0019820 CHEBI:43468 biolink:ChemicalSubstance (2R,3S)-3-isopropylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43468 CHEBI:111006 biolink:ChemicalSubstance maltose 6'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_111006 GO:0019809 biolink:MolecularActivity spermidine binding Binding to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. go-plus.json http://purl.obolibrary.org/obo/GO_0019809 GO:0019807 biolink:MolecularActivity aspartoacylase activity Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate. MetaCyc:ASPARTOACYLASE-RXN|Reactome:R-HSA-5691507|EC:3.5.1.15|RHEA:10872 go-plus.json N-acetylaspartate amidohydrolase activity|acetyl-aspartic deaminase activity|acylase II|N-acyl-L-aspartate amidohydrolase activity|aminoacylase II activity http://purl.obolibrary.org/obo/GO_0019807 CHEBI:43451 biolink:ChemicalSubstance hydrogen iodide go-plus.json http://purl.obolibrary.org/obo/CHEBI_43451 GO:0019808 biolink:MolecularActivity polyamine binding Binding to a polyamine, an organic compound containing two or more amino groups. go-plus.json http://purl.obolibrary.org/obo/GO_0019808 GO:0019805 biolink:BiologicalProcess quinolinate biosynthetic process The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. go-plus.json quinolinate biosynthesis|quinolinate anabolism|quinolinate synthesis|quinolinate formation http://purl.obolibrary.org/obo/GO_0019805 GO:0019806 biolink:MolecularActivity bromide peroxidase activity Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide. EC:1.11.1.18 go-plus.json bromoperoxidase activity http://purl.obolibrary.org/obo/GO_0019806 GO:0019803 biolink:BiologicalProcess peptidyl-aspartic acid carboxylation The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid. RESID:AA0304 go-plus.json http://purl.obolibrary.org/obo/GO_0019803 GO:0019804 biolink:CellularComponent obsolete quinolinate synthetase complex OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate. go-plus.json quinolinate synthetase complex http://purl.obolibrary.org/obo/GO_0019804 GO:0019801 biolink:BiologicalProcess cyclization of asparagine involved in intein-mediated protein splicing The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing. RESID:AA0302 go-plus.json cyclization of asparagine, during protein splicing http://purl.obolibrary.org/obo/GO_0019801 GO:0019802 biolink:BiologicalProcess cyclization of glutamine involved in intein-mediated protein splicing The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing. RESID:AA0303 go-plus.json cyclization of glutamine, during protein splicing http://purl.obolibrary.org/obo/GO_0019802 GO:0019800 biolink:BiologicalProcess peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain. RESID:AA0219 go-plus.json peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan http://purl.obolibrary.org/obo/GO_0019800 CHEBI:5870 biolink:ChemicalSubstance imidacloprid go-plus.json http://purl.obolibrary.org/obo/CHEBI_5870 chebi_ph7_3 GO:0030378 biolink:MolecularActivity serine racemase activity Catalysis of the synthesis of free D-serine from L-serine. RHEA:10980|MetaCyc:5.1.1.18-RXN|Reactome:R-HSA-9014766|EC:5.1.1.18 go-plus.json http://purl.obolibrary.org/obo/GO_0030378 GO:0030379 biolink:MolecularActivity neurotensin receptor activity, non-G protein-coupled Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins. go-plus.json non-G-protein coupled neurotensin receptor activity|neurotensin receptor activity, non-G-protein coupled|non G protein coupled neurotensin receptor activity|neurotensin receptor activity, non G protein coupled|non-G-protein-coupled neurotensin receptor activity http://purl.obolibrary.org/obo/GO_0030379 GO:0030376 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030376 GO:0030377 biolink:MolecularActivity urokinase plasminogen activator receptor activity Combining with the urokinase plasminogen activator to initiate a change in cell activity. Wikipedia:Urokinase_receptor go-plus.json urokinase plasminogen activator receptor|uPAR|U-plasminogen activator receptor activity http://purl.obolibrary.org/obo/GO_0030377 GO:0030374 biolink:MolecularActivity nuclear receptor coactivator activity A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. go-plus.json transcription factor activity, ligand-activated RNA polymerase II transcription factor binding|ligand-dependent nuclear receptor transcription co-activator activity|ligand-activated RNA polymerase II transcription factor binding transcription factor activity|nuclear receptor transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity http://purl.obolibrary.org/obo/GO_0030374 GO:0030375 biolink:MolecularActivity obsolete thyroid hormone receptor coactivator activity OBSOLETE. The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself. go-plus.json thyroid hormone receptor activator activity|thyroid hormone receptor co-activator activity http://purl.obolibrary.org/obo/GO_0030375 GO:0030372 biolink:MolecularActivity high molecular weight B cell growth factor receptor binding Binding to a high molecular weight B cell growth factor receptor. go-plus.json high molecular weight B lymphocyte growth factor receptor binding|high molecular weight B cell growth factor receptor ligand|high molecular weight B-lymphocyte growth factor receptor binding|high molecular weight B-cell growth factor receptor binding http://purl.obolibrary.org/obo/GO_0030372 GO:0030373 biolink:MolecularActivity high molecular weight B cell growth factor receptor activity Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity. go-plus.json HMW-BCGF receptor|high molecular weight B-cell growth factor receptor activity|high molecular weight B-lymphocyte growth factor receptor activity|high molecular weight B lymphocyte growth factor receptor activity http://purl.obolibrary.org/obo/GO_0030373 CHEBI:5686 biolink:ChemicalSubstance heterocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_5686 GO:0030370 biolink:MolecularActivity intercellular adhesion molecule-3 receptor binding Binding to a receptor for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1. go-plus.json ICAM-3 receptor ligand|ICAM-3 receptor binding|intercellular adhesion molecule-3 receptor ligand http://purl.obolibrary.org/obo/GO_0030370 GO:0030371 biolink:MolecularActivity translation repressor activity Antagonizes ribosome-mediated translation of mRNA into a polypeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0030371 GO:0030369 biolink:MolecularActivity ICAM-3 receptor activity Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues. go-plus.json http://purl.obolibrary.org/obo/GO_0030369 GO:0030367 biolink:MolecularActivity interleukin-17 receptor binding Binding to an interleukin-17 receptor. go-plus.json interleukin-17 receptor ligand|IL-17 http://purl.obolibrary.org/obo/GO_0030367 GO:0030368 biolink:MolecularActivity interleukin-17 receptor activity Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Wikipedia:Interleukin-17_receptor go-plus.json IL-17 receptor activity|IL-17R http://purl.obolibrary.org/obo/GO_0030368 GO:0030365 biolink:MolecularActivity obsolete cleavage stimulation factor activity OBSOLETE. A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide. go-plus.json cleavage stimulation factor activity|CstF http://purl.obolibrary.org/obo/GO_0030365 GO:0030366 biolink:MolecularActivity molybdopterin synthase activity Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis. Reactome:R-HSA-947541|EC:2.8.1.12|RHEA:26333 go-plus.json http://purl.obolibrary.org/obo/GO_0030366 GO:0030363 biolink:MolecularActivity obsolete pre-mRNA cleavage factor activity OBSOLETE. Any activity required for the process of mRNA cleavage. go-plus.json pre-mRNA cleavage factor activity http://purl.obolibrary.org/obo/GO_0030363 GO:0030364 biolink:MolecularActivity obsolete cleavage and polyadenylylation specificity factor activity OBSOLETE. A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions. go-plus.json cleavage and polyadenylylation specificity factor activity|cleavage and polyadenylation specificity factor activity|cleavage/polyadenylation specificity factor activity|CPSF http://purl.obolibrary.org/obo/GO_0030364 GO:0030361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030361 GO:0030362 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030362 CHEBI:5697 biolink:ChemicalSubstance palmitoyl-[acyl-carrier protein] go-plus.json http://purl.obolibrary.org/obo/CHEBI_5697 chebi_ph7_3 GO:0030360 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030360 GO:0030358 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030358 GO:0030359 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030359 GO:0030356 biolink:MolecularActivity obsolete small cytoplasmic ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json scRNP|small cytoplasmic ribonucleoprotein http://purl.obolibrary.org/obo/GO_0030356 GO:0030357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030357 GO:0005396 biolink:MolecularActivity obsolete transmembrane conductance regulator activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json transmembrane conductance regulator activity http://purl.obolibrary.org/obo/GO_0005396 GO:0005395 biolink:MolecularActivity obsolete eye pigment precursor transporter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out). go-plus.json http://purl.obolibrary.org/obo/GO_0005395 GO:0030354 biolink:MolecularActivity melanin-concentrating hormone activity The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0030354 GO:0030355 biolink:MolecularActivity obsolete small nucleolar ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json small nucleolar ribonucleoprotein|snoRNP http://purl.obolibrary.org/obo/GO_0030355 GO:0030352 biolink:MolecularActivity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0030352 GO:0030353 biolink:MolecularActivity fibroblast growth factor receptor antagonist activity Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist. go-plus.json FGF receptor antagonist activity|FGFR antagonist activity http://purl.obolibrary.org/obo/GO_0030353 GO:0030350 biolink:MolecularActivity iron-responsive element binding Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins. go-plus.json IRE binding http://purl.obolibrary.org/obo/GO_0030350 GO:0030351 biolink:MolecularActivity inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate. Reactome:R-HSA-1855163 go-plus.json http://purl.obolibrary.org/obo/GO_0030351 GO:0030349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030349 RO:0002380 biolink:OntologyClass RO:0002380 go-plus.json http://purl.obolibrary.org/obo/RO_0002380 GO:0030347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030347 GO:0030348 biolink:MolecularActivity syntaxin-3 binding Binding to a syntaxin-3 SNAP receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0030348 GO:0030345 biolink:MolecularActivity structural constituent of tooth enamel The action of a molecule that contributes to the structural integrity of tooth enamel. go-plus.json http://purl.obolibrary.org/obo/GO_0030345 GO:0030346 biolink:MolecularActivity protein phosphatase 2B binding Binding to a protein phosphatase 2B. go-plus.json protein phosphatase 3 binding|calcineurin binding http://purl.obolibrary.org/obo/GO_0030346 RO:0002385 biolink:OntologyClass has potential to developmentally contribute to x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y RO:0002385 go-plus.json http://purl.obolibrary.org/obo/RO_0002385 RO:0002387 biolink:OntologyClass has potential to develop into x has the potential to develop into y iff x develops into y or if x is capable of developing into y RO:0002387 go-plus.json http://purl.obolibrary.org/obo/RO_0002387 RO:0002388 biolink:OntologyClass has potential to directly develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y RO:0002388 go-plus.json http://purl.obolibrary.org/obo/RO_0002388 RO:0002384 biolink:OntologyClass has developmental potential involving x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). RO:0002384 go-plus.json http://purl.obolibrary.org/obo/RO_0002384 GO:0030343 biolink:MolecularActivity vitamin D3 25-hydroxylase activity Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O. MetaCyc:RXN-9829|Reactome:R-HSA-209845|RHEA:32903|Reactome:R-HSA-5602147 go-plus.json cholecalciferol 25-hydroxylase activity http://purl.obolibrary.org/obo/GO_0030343 GO:0030344 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030344 GO:0030341 biolink:MolecularActivity chondroitin AC lyase activity Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. MetaCyc:4.2.2.5-RXN|EC:4.2.2.5 go-plus.json chondroitinase activity|chondroitin AC eliminase activity|chondroitin lyase activity|chondroitinase AC|chondroitin sulfate lyase activity|ChnAC http://purl.obolibrary.org/obo/GO_0030341 GO:0030342 biolink:MolecularActivity 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol). Reactome:R-HSA-209765|Reactome:R-HSA-5602004|Reactome:R-HSA-211950 go-plus.json 1,25-(OH)2D3 24-hydroxylase activity|calcitriol 24-hydroxylase activity http://purl.obolibrary.org/obo/GO_0030342 GO:0030340 biolink:MolecularActivity hyaluronate lyase activity Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine. MetaCyc:HYALURONATE-LYASE-RXN|RHEA:50240|EC:4.2.2.1 go-plus.json hyaluronidase [but cf. EC:3.2.1.35 (hyalurononglucosaminidase) and EC:3.2.1.36 (hyaluronoglucuronidase)]|spreading factor activity|hyaluronidase activity|glucuronoglycosaminoglycan lyase activity|mucinase activity http://purl.obolibrary.org/obo/GO_0030340 CHEBI:5672 biolink:ChemicalSubstance heptan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_5672 chebi_ph7_3 GO:0030338 biolink:MolecularActivity CMP-N-acetylneuraminate monooxygenase activity Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O. MetaCyc:1.14.13.45-RXN|RHEA:16145|EC:1.14.18.2 go-plus.json cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity|N-acetylneuraminic monooxygenase activity|CMP-Neu5Ac hydroxylase activity|cytidine monophosphoacetylneuraminate monooxygenase activity|CMP-N-acetylneuraminate hydroxylase activity|CMP-N-acetylneuraminic acid hydroxylase activity|CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating) http://purl.obolibrary.org/obo/GO_0030338 GO:0030339 biolink:MolecularActivity fatty-acyl-ethyl-ester synthase activity Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol. EC:3.1.1.67|RHEA:16641|MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN go-plus.json FAEES activity|fatty-acyl ethyl ester synthase|FAEE synthase activity|long-chain-fatty-acyl-ethyl-ester acylhydrolase activity http://purl.obolibrary.org/obo/GO_0030339 CHEBI:149689 biolink:ChemicalSubstance D-dopa zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_149689 chebi_ph7_3 GO:0030336 biolink:BiologicalProcess negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. go-plus.json down-regulation of cell migration|downregulation of cell migration|down regulation of cell migration|inhibition of cell migration http://purl.obolibrary.org/obo/GO_0030336 GO:0030337 biolink:MolecularActivity DNA polymerase processivity factor activity An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it. go-plus.json processivity clamp|sliding clamp http://purl.obolibrary.org/obo/GO_0030337 GO:0005378 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005378 GO:0030334 biolink:BiologicalProcess regulation of cell migration Any process that modulates the frequency, rate or extent of cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0030334 GO:0030335 biolink:BiologicalProcess positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of cell migration. go-plus.json activation of cell migration|up regulation of cell migration|upregulation of cell migration|stimulation of cell migration|up-regulation of cell migration http://purl.obolibrary.org/obo/GO_0030335 GO:0005379 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005379 GO:0005376 biolink:MolecularActivity obsolete plasma membrane copper transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json plasma membrane copper transporter http://purl.obolibrary.org/obo/GO_0005376 RO:0002374 biolink:OntologyClass x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat RO:0002374 go-plus.json http://purl.obolibrary.org/obo/RO_0002374 GO:0005377 biolink:MolecularActivity obsolete intracellular copper ion transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json intracellular copper transporter|intracellular copper ion transporter http://purl.obolibrary.org/obo/GO_0005377 RO:0002376 biolink:OntologyClass RO:0002376 go-plus.json drains into http://purl.obolibrary.org/obo/RO_0002376 GO:0005375 biolink:MolecularActivity copper ion transmembrane transporter activity Enables the transfer of copper (Cu) ions from one side of a membrane to the other. Reactome:R-HSA-437300|RHEA:28703 go-plus.json plasma membrane copper transporter|intracellular copper ion transporter|copper uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005375 GO:0005372 biolink:MolecularActivity water transmembrane transporter activity Enables the transfer of water (H2O) from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0005372 GO:0005373 biolink:MolecularActivity obsolete heavy metal ion porter activity OBSOLETE. A transporter of heavy metal ions that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane. go-plus.json metal ion transporter|heavy metal ion porter activity http://purl.obolibrary.org/obo/GO_0005373 RO:0002371 biolink:OntologyClass RO:0002371 go-plus.json http://purl.obolibrary.org/obo/RO_0002371 GO:0005370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005370 RO:0002372 biolink:OntologyClass m has_muscle_origin s iff m is attaches_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. RO:0002372 go-plus.json http://purl.obolibrary.org/obo/RO_0002372 GO:0005371 biolink:MolecularActivity tricarboxylate secondary active transmembrane transporter activity Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json tricarboxylate carrier activity http://purl.obolibrary.org/obo/GO_0005371 PATO:0002505 biolink:OntologyClass nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. go-plus.json http://purl.obolibrary.org/obo/PATO_0002505 RO:0002373 biolink:OntologyClass m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. RO:0002373 go-plus.json http://purl.obolibrary.org/obo/RO_0002373 GO:0005380 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005380 NCBITaxon:1437180 biolink:OrganismalEntity Acrogymnospermae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1437180 NCBITaxon:1437183 biolink:OrganismalEntity Mesangiospermae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1437183 CHEBI:149690 biolink:ChemicalSubstance N-(fatty acyl)-L-phenylalanine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149690 chebi_ph7_3 GO:0030332 biolink:MolecularActivity cyclin binding Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0030332 GO:0030333 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030333 GO:0030330 biolink:BiologicalProcess DNA damage response, signal transduction by p53 class mediator A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. go-plus.json DNA damage response, activation of p53|p53-mediated DNA damage response|p53 signaling pathway|TP53 signaling pathway http://purl.obolibrary.org/obo/GO_0030330 GO:0030331 biolink:MolecularActivity estrogen receptor binding Binding to an estrogen receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0030331 GO:0030329 biolink:BiologicalProcess prenylcysteine metabolic process The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue. go-plus.json prenylcysteine metabolism http://purl.obolibrary.org/obo/GO_0030329 GO:0030327 biolink:BiologicalProcess prenylated protein catabolic process The chemical reactions and pathways resulting in the breakdown of prenylated proteins. go-plus.json prenylated protein catabolism|prenylated protein degradation|prenylated protein breakdown http://purl.obolibrary.org/obo/GO_0030327 GO:0030328 biolink:BiologicalProcess prenylcysteine catabolic process The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue. go-plus.json prenylcysteine catabolism|prenylcysteine degradation|prenylcysteine breakdown http://purl.obolibrary.org/obo/GO_0030328 GO:0030325 biolink:BiologicalProcess adrenal gland development The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. go-plus.json interrenal gland http://purl.obolibrary.org/obo/GO_0030325 GO:0030326 biolink:BiologicalProcess embryonic limb morphogenesis The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. go-plus.json http://purl.obolibrary.org/obo/GO_0030326 GO:0030323 biolink:BiologicalProcess respiratory tube development The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. go-plus.json http://purl.obolibrary.org/obo/GO_0030323 GO:0030324 biolink:BiologicalProcess lung development The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. go-plus.json http://purl.obolibrary.org/obo/GO_0030324 GO:0005388 biolink:MolecularActivity P-type calcium transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(in) = ADP + phosphate + Ca2+(out). MetaCyc:3.6.3.8-RXN|Reactome:R-HSA-418365|Reactome:R-HSA-427910|EC:7.2.2.10|Reactome:R-HSA-418309|Reactome:R-HSA-936883|RHEA:18105 go-plus.json sarco(endo)plasmic reticulum Ca2+-ATPase|calcium-transporting ATPase activity|calcium pump|calcium transmembrane transporter activity, phosphorylative mechanism|Ca2+-transporting ATPase activity|calcium-translocating P-type ATPase activity|calcium transporting ATPase activity|ATP-dependent calcium transmembrane transporter activity|ATPase-coupled calcium transmembrane transporter activity|calcium efflux ATPase|Ca(2+)-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0005388 GO:0005385 biolink:MolecularActivity zinc ion transmembrane transporter activity Enables the transfer of zinc (Zn) ions from one side of a membrane to the other. Reactome:R-HSA-5654125|Reactome:R-HSA-442422|Reactome:R-HSA-442345|Reactome:R-HSA-442387|Reactome:R-HSA-442405|Reactome:R-HSA-442393|Reactome:R-HSA-435366|Reactome:R-HSA-437084|Reactome:R-HSA-437085|Reactome:R-HSA-437129|Reactome:R-HSA-437139|RHEA:29351|Reactome:R-HSA-437136|Reactome:R-HSA-435375|Reactome:R-HSA-442317 go-plus.json zinc, iron permease activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|zinc, cadmium uptake permease activity|cobalt, zinc uptake permease activity http://purl.obolibrary.org/obo/GO_0005385 GO:0005386 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005386 NCBITaxon:766764 biolink:OrganismalEntity Debaryomycetaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_766764 GO:0005384 biolink:MolecularActivity manganese ion transmembrane transporter activity Enables the transfer of manganese (Mn) ions from one side of a membrane to the other. RHEA:28699|Reactome:R-HSA-8959798 go-plus.json http://purl.obolibrary.org/obo/GO_0005384 GO:0005381 biolink:MolecularActivity iron ion transmembrane transporter activity Enables the transfer of iron (Fe) ions from one side of a membrane to the other. Reactome:R-HSA-904830|Reactome:R-HSA-917936|Reactome:R-HSA-435349|Reactome:R-HSA-5623558|Reactome:R-HSA-5655733 go-plus.json iron transporter activity|zinc, iron permease activity|multicopper ferroxidase iron transport mediator activity|transmembrane iron ion permease activity|iron channel activity|iron cation channel activity|transmembrane iron permease activity http://purl.obolibrary.org/obo/GO_0005381 CHEBI:149673 biolink:ChemicalSubstance (1S,2R)-ephedrine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149673 chebi_ph7_3 GO:0005382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005382 GO:0005390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005390 GO:0005391 biolink:MolecularActivity P-type sodium:potassium-exchanging transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in). MetaCyc:3.6.3.9-RXN|Reactome:R-HSA-936897|EC:7.2.2.13|Wikipedia:ATPase,_Na%2B/K%2B_transporting,_alpha_1|TC:3.A.3.1.1|RHEA:18353 go-plus.json Na(+)/K(+)-ATPase activity|Na+/K+-ATPase activity|sodium/potassium-transporting ATPase activity|Na+,K+-ATPase activity|sodium:potassium-exchanging ATPase activity|Na,K-activated ATPase activity|Na(+)/K(+)-exchanging ATPase activity|Na+/K+-exchanging ATPase activity|P-type sodium:potassium-exchanging ATPase activity|sodium pump|sodium/potassium-exchanging ATPase activity|sodium:potassium exchanging ATPase activity http://purl.obolibrary.org/obo/GO_0005391 RO:0002356 biolink:OntologyClass results in specification of The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. RO:0002356 go-plus.json http://purl.obolibrary.org/obo/RO_0002356 NCBITaxon:1437197 biolink:OrganismalEntity Petrosaviidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1437197 GO:0030321 biolink:BiologicalProcess transepithelial chloride transport The directed movement of chloride ions from one side of an epithelium to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0030321 GO:0030322 biolink:BiologicalProcess stabilization of membrane potential The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0030322 GO:0030320 biolink:BiologicalProcess cellular monovalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030320 GO:0030318 biolink:BiologicalProcess melanocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. go-plus.json melanocyte cell differentiation|melanophore differentiation http://purl.obolibrary.org/obo/GO_0030318 GO:0030319 biolink:BiologicalProcess obsolete cellular di-, tri-valent inorganic anion homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions at the level of a cell. go-plus.json cellular di-, tri-valent inorganic anion homeostasis http://purl.obolibrary.org/obo/GO_0030319 GO:0030316 biolink:BiologicalProcess osteoclast differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. go-plus.json osteoclast cell differentiation http://purl.obolibrary.org/obo/GO_0030316 GO:0030317 biolink:BiologicalProcess flagellated sperm motility The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. Wikipedia:Sperm_motility go-plus.json sperm flagellum movement involved in flagellated sperm movement|sperm flagellum movement|sperm flagellum movement involved in flagellated sperm motility|sperm motility|flagellated sperm movement|sperm movement http://purl.obolibrary.org/obo/GO_0030317 GO:0005358 biolink:MolecularActivity high-affinity glucose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high-affinity hydrogen:glucose transporter activity|high-affinity hydrogen/glucose transporter activity|high-affinity hydrogen:glucose symporter activity http://purl.obolibrary.org/obo/GO_0005358 GO:0030314 biolink:CellularComponent junctional membrane complex Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules). go-plus.json triad junction http://purl.obolibrary.org/obo/GO_0030314 GO:0030315 biolink:CellularComponent T-tubule Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane. Wikipedia:T-tubule go-plus.json triad|transverse tubule http://purl.obolibrary.org/obo/GO_0030315 GO:0005359 biolink:MolecularActivity low-affinity glucose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. go-plus.json low-affinity hydrogen:glucose symporter activity|low-affinity hydrogen:glucose transporter activity|low-affinity hydrogen/glucose transporter activity http://purl.obolibrary.org/obo/GO_0005359 GO:0005356 biolink:MolecularActivity glucose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. go-plus.json hydrogen:glucose symporter activity|transepithelial hydrogen:glucose transporter activity|hydrogen:glucose transporter activity|transepithelial hydrogen/glucose transporter activity|transepithelial hydrogen:glucose symporter activity http://purl.obolibrary.org/obo/GO_0005356 GO:0030312 biolink:CellularComponent external encapsulating structure A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. go-plus.json http://purl.obolibrary.org/obo/GO_0030312 goslim_chembl|goslim_plant|goslim_pir|goslim_drosophila|goslim_generic GO:0030313 biolink:CellularComponent cell envelope An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present. Wikipedia:Cell_envelope go-plus.json http://purl.obolibrary.org/obo/GO_0030313 goslim_pir GO:0005357 biolink:MolecularActivity obsolete constitutive glucose:proton symporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. go-plus.json constitutive hydrogen:glucose transporter activity|constitutive hydrogen/glucose transporter activity|constitutive hydrogen:glucose symporter activity http://purl.obolibrary.org/obo/GO_0005357 RO:0002352 biolink:OntologyClass input of inverse of has input RO:0002352 go-plus.json http://purl.obolibrary.org/obo/RO_0002352 GO:0005354 biolink:MolecularActivity galactose transmembrane transporter activity Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. go-plus.json galactose/glucose (methylgalactoside) porter activity http://purl.obolibrary.org/obo/GO_0005354 GO:0005355 biolink:MolecularActivity glucose transmembrane transporter activity Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other. Reactome:R-HSA-5653873|Reactome:R-HSA-499981 go-plus.json galactose/glucose (methylgalactoside) porter activity|glucose permease activity|lactose/glucose efflux transporter activity http://purl.obolibrary.org/obo/GO_0005355 RO:0002353 biolink:OntologyClass output_of inverse of has output RO:0002353 go-plus.json http://purl.obolibrary.org/obo/RO_0002353 GO:0005352 biolink:MolecularActivity alpha-glucoside:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose. go-plus.json general alpha-glucoside:proton symporter activity|alpha-glucoside:hydrogen symporter activity|general alpha-glucoside transporter activity|general alpha-glucoside:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0005352 RO:0002354 biolink:OntologyClass formed as result of RO:0002354 go-plus.json http://purl.obolibrary.org/obo/RO_0002354 GO:0005353 biolink:MolecularActivity fructose transmembrane transporter activity Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. Reactome:R-HSA-189222 go-plus.json fructose porter activity|fructose permease activity http://purl.obolibrary.org/obo/GO_0005353 RO:0002355 biolink:OntologyClass results in structural organization of A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity. RO:0002355 go-plus.json http://purl.obolibrary.org/obo/RO_0002355 GO:0005350 biolink:MolecularActivity pyrimidine nucleobase transmembrane transporter activity Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other. go-plus.json pyrimidine base transmembrane transporter activity|pyrimidine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005350 GO:0005351 biolink:MolecularActivity carbohydrate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in). TC:2.A.1.1 go-plus.json cation/sugar symporter activity|hydrogen:sugar symporter activity|sugar transporter|sugar porter activity|sugar efflux transmembrane transporter activity|proton:sugar symporter activity|sugar:hydrogen symporter activity|sugar:proton symporter activity|sugar:hydrogen ion symporter activity|hydrogen:sugar transporter activity|lactose/glucose efflux transporter activity http://purl.obolibrary.org/obo/GO_0005351 RO:0002350 biolink:OntologyClass RO:0002350 go-plus.json http://purl.obolibrary.org/obo/RO_0002350 RO:0002351 biolink:OntologyClass RO:0002351 go-plus.json http://purl.obolibrary.org/obo/RO_0002351 RO:0002349 biolink:OntologyClass results in determination of p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment. RO:0002349 go-plus.json http://purl.obolibrary.org/obo/RO_0002349 RO:0002345 biolink:OntologyClass exports Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the end location of c is part of the region that surrounds s. RO:0002345 go-plus.json http://purl.obolibrary.org/obo/RO_0002345 RO:0002348 biolink:OntologyClass results in commitment to p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type. RO:0002348 go-plus.json http://purl.obolibrary.org/obo/RO_0002348 GO:0030310 biolink:BiologicalProcess poly-N-acetyllactosamine catabolic process The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. go-plus.json poly-N-acetyllactosamine degradation|poly-N-acetyllactosamine catabolism|poly-N-acetyllactosamine breakdown http://purl.obolibrary.org/obo/GO_0030310 GO:0030311 biolink:BiologicalProcess poly-N-acetyllactosamine biosynthetic process The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. go-plus.json poly-N-acetyllactosamine biosynthesis|poly-N-acetyllactosamine anabolism|poly-N-acetyllactosamine synthesis|poly-N-acetyllactosamine formation http://purl.obolibrary.org/obo/GO_0030311 GO:0019991 biolink:BiologicalProcess septate junction assembly The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space. go-plus.json http://purl.obolibrary.org/obo/GO_0019991 GO:0019992 biolink:MolecularActivity diacylglycerol binding Binding to a diacylglycerol, a diester of glycerol and two fatty acids. go-plus.json http://purl.obolibrary.org/obo/GO_0019992 GO:0019990 biolink:BiologicalProcess pteridine catabolic process The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group. go-plus.json pteridine breakdown|pteridine catabolism|pteridine degradation http://purl.obolibrary.org/obo/GO_0019990 GO:0030307 biolink:BiologicalProcess positive regulation of cell growth Any process that activates or increases the frequency, rate, extent or direction of cell growth. go-plus.json activation of cell growth|stimulation of cell growth|up-regulation of cell growth|upregulation of cell growth|up regulation of cell growth http://purl.obolibrary.org/obo/GO_0030307 GO:0030308 biolink:BiologicalProcess negative regulation of cell growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. go-plus.json down-regulation of cell growth|inhibition of cell growth|down regulation of cell growth|downregulation of cell growth http://purl.obolibrary.org/obo/GO_0030308 GO:0030305 biolink:MolecularActivity heparanase activity Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains. Reactome:R-HSA-1678694|Reactome:R-HSA-1667005 go-plus.json heparinase activity http://purl.obolibrary.org/obo/GO_0030305 GO:0030306 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030306 GO:0030303 biolink:MolecularActivity obsolete stromelysin 2 activity OBSOLETE. Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak. go-plus.json stromelysin 2 activity|matrix metalloproteinase 10 activity|MMP-10|proteoglycanase 2|transin 2 activity http://purl.obolibrary.org/obo/GO_0030303 GO:0005369 biolink:MolecularActivity taurine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in). go-plus.json sodium/chloride-dependent taurine transporter http://purl.obolibrary.org/obo/GO_0005369 GO:0030304 biolink:MolecularActivity obsolete trypsin inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase trypsin. go-plus.json trypsin inhibitor activity http://purl.obolibrary.org/obo/GO_0030304 GO:0005367 biolink:MolecularActivity myo-inositol:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in). Reactome:R-HSA-429663 go-plus.json myo-inositol-sodium cotransporter activity http://purl.obolibrary.org/obo/GO_0005367 GO:0030301 biolink:BiologicalProcess cholesterol transport The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0030301 GO:0030302 biolink:BiologicalProcess deoxynucleotide transport The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0030302 GO:0005368 biolink:MolecularActivity taurine transmembrane transporter activity Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats. go-plus.json http://purl.obolibrary.org/obo/GO_0005368 RO:0002341 biolink:OntologyClass results in transport along Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l RO:0002341 go-plus.json http://purl.obolibrary.org/obo/RO_0002341 GO:0005365 biolink:MolecularActivity myo-inositol transmembrane transporter activity Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms. go-plus.json vitamin Bh transporter activity http://purl.obolibrary.org/obo/GO_0005365 GO:0005366 biolink:MolecularActivity myo-inositol:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in). RHEA:60364|Reactome:R-HSA-429101 go-plus.json myo-inositol:hydrogen symporter activity|hydrogen/myo-inositol transporter activity http://purl.obolibrary.org/obo/GO_0005366 RO:0002342 biolink:OntologyClass results in transport across Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. RO:0002342 go-plus.json http://purl.obolibrary.org/obo/RO_0002342 RO:0002343 biolink:OntologyClass results in growth of RO:0002343 go-plus.json http://purl.obolibrary.org/obo/RO_0002343 GO:0005363 biolink:MolecularActivity maltose transmembrane transporter activity Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. RHEA:33171 go-plus.json maltose porter activity http://purl.obolibrary.org/obo/GO_0005363 GO:0005364 biolink:MolecularActivity maltose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in). go-plus.json hydrogen/maltose transporter activity|maltose permease|maltose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0005364 RO:0002344 biolink:OntologyClass results in transport to from or in RO:0002344 go-plus.json http://purl.obolibrary.org/obo/RO_0002344 GO:0005361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005361 GO:0005362 biolink:MolecularActivity low-affinity glucose:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Reactome:R-HSA-429567 go-plus.json low-affinity glucose-sodium cotransporter activity http://purl.obolibrary.org/obo/GO_0005362 GO:0030309 biolink:BiologicalProcess poly-N-acetyllactosamine metabolic process The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. go-plus.json poly-N-acetyllactosamine metabolism http://purl.obolibrary.org/obo/GO_0030309 GO:0005360 biolink:MolecularActivity insulin-responsive glucose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. go-plus.json transepithelial hydrogen/glucose transporter activity|insulin-responsive hydrogen:glucose transporter activity|insulin-responsive hydrogen:glucose symporter activity http://purl.obolibrary.org/obo/GO_0005360 RO:0002340 biolink:OntologyClass imports Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the start location of c is part of the region that surrounds s. RO:0002340 go-plus.json http://purl.obolibrary.org/obo/RO_0002340 RO:0002338 biolink:OntologyClass has target start location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. RO:0002338 go-plus.json http://purl.obolibrary.org/obo/RO_0002338 RO:0002339 biolink:OntologyClass has target end location This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. RO:0002339 go-plus.json http://purl.obolibrary.org/obo/RO_0002339 RO:0002334 biolink:OntologyClass regulated by inverse of regulates RO:0002334 go-plus.json http://purl.obolibrary.org/obo/RO_0002334 RO:0002335 biolink:OntologyClass negatively regulated by inverse of negatively regulates RO:0002335 go-plus.json http://purl.obolibrary.org/obo/RO_0002335 RO:0002336 biolink:OntologyClass positively regulated by inverse of positively regulates RO:0002336 go-plus.json http://purl.obolibrary.org/obo/RO_0002336 RO:0002337 biolink:OntologyClass related via localization to A relationship that holds via some process of localization RO:0002337 go-plus.json http://purl.obolibrary.org/obo/RO_0002337 GO:0030300 biolink:BiologicalProcess regulation of intestinal cholesterol absorption Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption. go-plus.json http://purl.obolibrary.org/obo/GO_0030300 RO:0002331 biolink:OntologyClass involved in c involved_in p if and only if c enables some process p', and p' is part of p RO:0002331 go-plus.json http://purl.obolibrary.org/obo/RO_0002331 RO:0002332 biolink:OntologyClass regulates levels of p regulates levels of c if p regulates some amount (PATO:0000070) of c RO:0002332 go-plus.json http://purl.obolibrary.org/obo/RO_0002332 RO:0002333 biolink:OntologyClass enabled by inverse of enables RO:0002333 go-plus.json http://purl.obolibrary.org/obo/RO_0002333 CHEBI:67375 biolink:ChemicalSubstance noreugenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_67375 RO:0002327 biolink:OntologyClass enables RO:0002327 go-plus.json http://purl.obolibrary.org/obo/RO_0002327 RO:0002328 biolink:OntologyClass functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. RO:0002328 go-plus.json http://purl.obolibrary.org/obo/RO_0002328 RO:0002329 biolink:OntologyClass part of structure that is capable of this relation holds between c and p when c is part of some c', and c' is capable of p. RO:0002329 go-plus.json http://purl.obolibrary.org/obo/RO_0002329 RO:0002323 biolink:OntologyClass mereotopologically related to A mereological relationship or a topological relationship RO:0002323 go-plus.json http://purl.obolibrary.org/obo/RO_0002323 RO:0002324 biolink:OntologyClass developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) RO:0002324 go-plus.json http://purl.obolibrary.org/obo/RO_0002324 RO:0002320 biolink:OntologyClass evolutionarily related to A relationship that holds via some environmental process RO:0002320 go-plus.json http://purl.obolibrary.org/obo/RO_0002320 RO:0002322 biolink:OntologyClass RO:0002322 go-plus.json adapted_for http://purl.obolibrary.org/obo/RO_0002322 UBERON:0004099 biolink:AnatomicalEntity joint space of elbow Joint cavity shared by all the joints of the elbow. The elbow joint is a compound joint that actually comprises three separate joints: the joints connecting the upper and lower arm: 1) Articulatio humero-ulnaris and 2) Articulatio humero-radialis as well as the proximal joint connecting the forarm bones: 3) Articulatio radio-ulnaris proximalis. All three share a joint cavity which is highly sinuated/scalloped/coved. Joint spaces of the elbow summarizes the joint cavity shared by all three adjoining joints of the elbow joint. go-plus.json synovial cavity of elbow joint http://purl.obolibrary.org/obo/UBERON_0004099 RO:0002313 biolink:OntologyClass transports or maintains localization of Holds between p and c when p is a localization process (localization covers maintenance of localization as well as its establishment) and the outcome of this process is to regulate the localization of c. RO:0002313 go-plus.json http://purl.obolibrary.org/obo/RO_0002313 RO:0002314 biolink:OntologyClass characteristic of part of q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. RO:0002314 go-plus.json http://purl.obolibrary.org/obo/RO_0002314 RO:0002315 biolink:OntologyClass results in acquisition of features of The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity RO:0002315 go-plus.json http://purl.obolibrary.org/obo/RO_0002315 UBERON:0004088 biolink:AnatomicalEntity orbital region The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present go-plus.json orbital content|content of orbital part of eye|orbital part of eye|orbital part of face|eye region|ocular and peri-ocular region|ocular region http://purl.obolibrary.org/obo/UBERON_0004088 RO:0002305 biolink:OntologyClass causally upstream of, negative effect RO:0002305 go-plus.json http://purl.obolibrary.org/obo/RO_0002305 UBERON:0004089 biolink:AnatomicalEntity midface The middle of the face including the nose and its associated bony structures[MW]. go-plus.json midface/lower face|lower face|snout http://purl.obolibrary.org/obo/UBERON_0004089 UBERON:0004086 biolink:AnatomicalEntity brain ventricle one of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid go-plus.json cerebral ventricle|region of ventricular system of brain|brain ventricles http://purl.obolibrary.org/obo/UBERON_0004086 CHEBI:18418 biolink:ChemicalSubstance (RS)-norcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18418 UBERON:0004087 biolink:AnatomicalEntity vena cava Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart. go-plus.json venae cavae|caval vein http://purl.obolibrary.org/obo/UBERON_0004087 CHEBI:18419 biolink:ChemicalSubstance lactaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18419 chebi_ph7_3 CHEBI:18416 biolink:ChemicalSubstance N-[(R)-pantothenoyl]-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18416 CHEBI:18417 biolink:ChemicalSubstance (RS)-coclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18417 CHEBI:18415 biolink:ChemicalSubstance N-formimidoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18415 RO:0002304 biolink:OntologyClass causally upstream of, positive effect RO:0002304 go-plus.json http://purl.obolibrary.org/obo/RO_0002304 CHEBI:18412 biolink:ChemicalSubstance N(omega)-phospho-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18412 CHEBI:18413 biolink:ChemicalSubstance 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18413 CHEBI:18410 biolink:ChemicalSubstance N-formylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18410 chebi_ph7_3 CHEBI:18411 biolink:ChemicalSubstance laminarabiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18411 chebi_ph7_3 CHEBI:18409 biolink:ChemicalSubstance (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18409 CHEBI:18407 biolink:ChemicalSubstance hydrogen cyanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18407 chebi_ph7_3 CHEBI:18408 biolink:ChemicalSubstance cobamamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18408 chebi_ph7_3 UBERON:0004073 biolink:AnatomicalEntity cerebellum interpositus nucleus The nucleus composed of the globose and emoliform nuclei of the cerebellum; in some mammalian species the globose nucleus is not distinguishable go-plus.json interposed nucleus of the cerebellum|interpositus nucleus|interposed nucleus of the cerebellum|interposed nucleus|interposed nucleus of cerebellum|interpositus http://purl.obolibrary.org/obo/UBERON_0004073 CHEBI:18405 biolink:ChemicalSubstance pyridoxal 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18405 CHEBI:18406 biolink:ChemicalSubstance AICA ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18406 CHEBI:18403 biolink:ChemicalSubstance L-arabinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18403 chebi_ph7_3 CHEBI:18404 biolink:ChemicalSubstance 3-methylcatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18404 chebi_ph7_3 CHEBI:18401 biolink:ChemicalSubstance phenylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18401 chebi_ph7_3 CHEBI:18402 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18402 CHEBI:18400 biolink:ChemicalSubstance 2-hydroxy-1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18400 GO:0030390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030390 GO:0030391 biolink:BiologicalProcess fructosamine biosynthetic process The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group. go-plus.json fructosamine formation|fructosamine biosynthesis|fructosamine anabolism|fructosamine synthesis http://purl.obolibrary.org/obo/GO_0030391 GO:0030398 biolink:BiologicalProcess peroxisomal membrane disassembly The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation. go-plus.json peroxisomal membrane degradation|peroxisomal membrane breakdown|peroxisomal membrane catabolism http://purl.obolibrary.org/obo/GO_0030398 GO:0030399 biolink:BiologicalProcess autophagosome membrane disassembly The controlled breakdown of the membranes of autophagosomes. go-plus.json autophagic membrane degradation|autophagic vacuole membrane disassembly|autophagic membrane catabolism|autophagic membrane breakdown http://purl.obolibrary.org/obo/GO_0030399 GO:0030396 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030396 GO:0030397 biolink:BiologicalProcess membrane disassembly The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. go-plus.json membrane catabolism|membrane degradation|membrane breakdown http://purl.obolibrary.org/obo/GO_0030397 GO:0030394 biolink:BiologicalProcess fructoseglycine metabolic process The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group. go-plus.json fructoseglycine metabolism http://purl.obolibrary.org/obo/GO_0030394 GO:0030395 biolink:MolecularActivity lactose binding Binding to lactose, a disaccharide of glucose and galactose, the carbohydrate of milk. go-plus.json http://purl.obolibrary.org/obo/GO_0030395 GO:0030392 biolink:BiologicalProcess fructosamine catabolic process The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group. go-plus.json fructosamine degradation|fructosamine catabolism|fructosamine breakdown http://purl.obolibrary.org/obo/GO_0030392 GO:0030393 biolink:BiologicalProcess fructoselysine metabolic process The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group. go-plus.json fructoselysine metabolism http://purl.obolibrary.org/obo/GO_0030393 GO:0030389 biolink:BiologicalProcess fructosamine metabolic process The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group. go-plus.json fructosamine metabolism http://purl.obolibrary.org/obo/GO_0030389 GO:0030380 biolink:MolecularActivity interleukin-17E receptor binding Binding to an interleukin-17E receptor. go-plus.json interleukin-17E receptor ligand|IL-17E http://purl.obolibrary.org/obo/GO_0030380 NCBITaxon:30319 biolink:OrganismalEntity Pipoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_30319 GO:0030387 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030387 GO:0030388 biolink:BiologicalProcess fructose 1,6-bisphosphate metabolic process The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. go-plus.json fructose 1,6-bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0030388 GO:0030385 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030385 GO:0030386 biolink:CellularComponent ferredoxin-thioredoxin reductase complex A protein complex that possesses ferredoxin-thioredoxin reductase activity. go-plus.json ferredoxin:thioredoxin reductase complex http://purl.obolibrary.org/obo/GO_0030386 GO:0030383 biolink:BiologicalProcess obsolete host-pathogen interaction OBSOLETE. Any interaction between a pathogen and its host organism. go-plus.json host-pathogen interaction http://purl.obolibrary.org/obo/GO_0030383 GO:0030384 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030384 GO:0030381 biolink:BiologicalProcess chorion-containing eggshell pattern formation The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects. go-plus.json http://purl.obolibrary.org/obo/GO_0030381 GO:0030382 biolink:BiologicalProcess sperm mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm. go-plus.json sperm mitochondrion organization and biogenesis|sperm mitochondria organization and biogenesis|sperm mitochondria organisation http://purl.obolibrary.org/obo/GO_0030382 CHEBI:82929 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82929 chebi_ph7_3 CHEBI:18360 biolink:ChemicalSubstance 13-(2-methylcrotonoyloxy)lupanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18360 CHEBI:18361 biolink:ChemicalSubstance diphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18361 CHEBI:82927 biolink:ChemicalSubstance 1-palmitoyl-2-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82927 chebi_ph7_3 CHEBI:82928 biolink:ChemicalSubstance 1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82928 chebi_ph7_3 CHEBI:57969 biolink:ChemicalSubstance imidazol-4-ylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57969 chebi_ph7_3 CHEBI:82925 biolink:ChemicalSubstance 1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82925 chebi_ph7_3 CHEBI:57967 biolink:ChemicalSubstance ADP-D-ribose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57967 chebi_ph7_3 CHEBI:57968 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-glutamate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57968 chebi_ph7_3 CHEBI:82924 biolink:ChemicalSubstance 1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82924 chebi_ph7_3 CHEBI:82921 biolink:ChemicalSubstance 1,2-dioctadecanoyl-sn-glycerol-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82921 chebi_ph7_3 UBERON:0004141 biolink:AnatomicalEntity heart tube An epithelial tube that will give rise to the mature heart. go-plus.json endocardial tube|endocardial heart tube|embryonic heart tube http://purl.obolibrary.org/obo/UBERON_0004141 CHEBI:33992 biolink:ChemicalSubstance (-)-catechin go-plus.json http://purl.obolibrary.org/obo/CHEBI_33992 chebi_ph7_3 UBERON:0004142 biolink:AnatomicalEntity outflow tract septum The outflow tract septum is a partition in the outflow tract go-plus.json http://purl.obolibrary.org/obo/UBERON_0004142 UBERON:0004140 biolink:AnatomicalEntity primary heart field A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. go-plus.json primary heart field|FHF|heart field|first heart field|PHF http://purl.obolibrary.org/obo/UBERON_0004140 CHEBI:18359 biolink:ChemicalSubstance holo-[acyl-carrier protein] go-plus.json http://purl.obolibrary.org/obo/CHEBI_18359 chebi_ph7_3 CHEBI:57965 biolink:ChemicalSubstance deacetoxyvindolinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57965 chebi_ph7_3 CHEBI:18357 biolink:ChemicalSubstance (R)-noradrenaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_18357 CHEBI:18358 biolink:ChemicalSubstance methoxsalen go-plus.json http://purl.obolibrary.org/obo/CHEBI_18358 chebi_ph7_3 CHEBI:57966 biolink:ChemicalSubstance beta-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57966 chebi_ph7_3 CHEBI:18355 biolink:ChemicalSubstance 2-hydroxypenta-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18355 CHEBI:57963 biolink:ChemicalSubstance vitexin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57963 chebi_ph7_3 UBERON:0004149 biolink:AnatomicalEntity ventriculo bulbo valve A heart valve located between the ventricle and bulbus arteriosus. go-plus.json bulboventricular valve http://purl.obolibrary.org/obo/UBERON_0004149 CHEBI:18356 biolink:ChemicalSubstance pyrroloquinoline quinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18356 CHEBI:57964 biolink:ChemicalSubstance GDP-4-dehydro-6-deoxy-alpha-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57964 chebi_ph7_3 CHEBI:18353 biolink:ChemicalSubstance vanillyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18353 chebi_ph7_3 CHEBI:18354 biolink:ChemicalSubstance (R)-2-hydroxypropyl-CoM go-plus.json http://purl.obolibrary.org/obo/CHEBI_18354 CHEBI:57962 biolink:ChemicalSubstance 5-hydroxymethyldeoxycytidylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57962 chebi_ph7_3 UBERON:0004148 biolink:AnatomicalEntity cardiac vein Vein of heart that drains the myocardium go-plus.json cardiac vein|coronary vein|heart vein|coronary vein|vein of heart http://purl.obolibrary.org/obo/UBERON_0004148 CHEBI:18351 biolink:ChemicalSubstance 4-hydroxyhexan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_18351 chebi_ph7_3 UBERON:0004145 biolink:AnatomicalEntity outflow tract The outflow tract is the portion of the heart through which blood flows into the arteries go-plus.json arterial (outflow) pole|heart outflow tract|cardiac outflow tract http://purl.obolibrary.org/obo/UBERON_0004145 NCBITaxon:188937 biolink:OrganismalEntity Methanosarcina acetivorans C2A go-plus.json Methanosarcina acetivorans str. C2A http://purl.obolibrary.org/obo/NCBITaxon_188937 UBERON:0004146 biolink:AnatomicalEntity His-Purkinje system The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles go-plus.json HPS|His-Purkinji network|ventricular conduction system|VCS http://purl.obolibrary.org/obo/UBERON_0004146 CHEBI:18350 biolink:ChemicalSubstance isoquinolin-1(2H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_18350 chebi_ph7_3 CHEBI:82939 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82939 chebi_ph7_3 CHEBI:57958 biolink:ChemicalSubstance (R)-2,4-dihydroxy-3-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57958 chebi_ph7_3 CHEBI:57959 biolink:ChemicalSubstance L-kynurenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57959 chebi_ph7_3 CHEBI:57956 biolink:ChemicalSubstance 3-amino-3-(4-hydroxyphenyl)propanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57956 chebi_ph7_3 CHEBI:57957 biolink:ChemicalSubstance lipid X(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57957 chebi_ph7_3 CHEBI:82930 biolink:ChemicalSubstance 3-(3-amino-3-carboxypropyl)uridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82930 chebi_ph7_3 GO:0019908 biolink:CellularComponent nuclear cyclin-dependent protein kinase holoenzyme complex Cyclin-dependent protein kinase (CDK) complex found in the nucleus. go-plus.json CDK holoenzyme http://purl.obolibrary.org/obo/GO_0019908 GO:0019909 biolink:MolecularActivity [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity Binds to and modulates of the activity of [pyruvate dehydrogenase (lipoamide)] phosphatase. go-plus.json [pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0019909 GO:0019906 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019906 GO:0019907 biolink:CellularComponent cyclin-dependent protein kinase activating kinase holoenzyme complex A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH. go-plus.json CAK complex|CDK-activating kinase complex http://purl.obolibrary.org/obo/GO_0019907 GO:0019904 biolink:MolecularActivity protein domain specific binding Binding to a specific domain of a protein. go-plus.json protein domain-specific binding http://purl.obolibrary.org/obo/GO_0019904 goslim_chembl UBERON:0004132 biolink:AnatomicalEntity trigeminal sensory nucleus The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. The nucleus is divided into three parts, from rostral to caudal (top to bottom in humans): * The mesencephalic nucleus * The chief sensory nucleus (or pontine nucleus or main sensory nucleus or primary nucleus) * The spinal trigeminal nucleus[WP]. go-plus.json sensory trigeminal nucleus|trigeminal sensory nucleus|sensory trigeminal nuclei|sensory trigeminal V nucleus|trigeminal V sensory nucleus http://purl.obolibrary.org/obo/UBERON_0004132 UBERON:0004133 biolink:AnatomicalEntity salivatory nucleus . go-plus.json salivary nucleus http://purl.obolibrary.org/obo/UBERON_0004133 GO:0019905 biolink:MolecularActivity syntaxin binding Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse. go-plus.json syntaxin-6 binding|syntaxin-5 binding|syntaxin-2 binding|syntaxin-13 binding http://purl.obolibrary.org/obo/GO_0019905 UBERON:0004130 biolink:AnatomicalEntity cerebellar layer A cortical cell layer of the cerebellum. Examples: the granular (inner+outer) layer, molecular layer, Purkinje cell layer, and the ventricular layer of the embryo. go-plus.json layer of cerebellum|gray matter layer of cerebellum|layer of cerebellar cortex|cell layer of cerebellar cortex|cytoarchitectural part of the cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 GO:0019902 biolink:MolecularActivity phosphatase binding Binding to a phosphatase. go-plus.json http://purl.obolibrary.org/obo/GO_0019902 GO:0019903 biolink:MolecularActivity protein phosphatase binding Binding to a protein phosphatase. go-plus.json http://purl.obolibrary.org/obo/GO_0019903 GO:0019900 biolink:MolecularActivity kinase binding Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group. go-plus.json http://purl.obolibrary.org/obo/GO_0019900 GO:0019901 biolink:MolecularActivity protein kinase binding Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0019901 CHEBI:18348 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18348 CHEBI:18349 biolink:ChemicalSubstance N(1)-(5-phospho-D-ribosyl)glycinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18349 CHEBI:18346 biolink:ChemicalSubstance vanillin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18346 chebi_ph7_3 CHEBI:57954 biolink:ChemicalSubstance 3-cyano-L-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57954 CHEBI:57955 biolink:ChemicalSubstance 6-O-phosphonato-D-glucono-1,5-lactone(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57955 chebi_ph7_3 CHEBI:18347 biolink:ChemicalSubstance L-norleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18347 CHEBI:57952 biolink:ChemicalSubstance sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57952 chebi_ph7_3 CHEBI:18344 biolink:ChemicalSubstance kynurenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18344 UBERON:0004138 biolink:AnatomicalEntity somitomeric trunk muscle The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004138 UBERON:0004139 biolink:AnatomicalEntity cardiogenic plate The first recognizable structure derived from the heart field go-plus.json myocardial plate|cardiogenic crescent|cardiac crescent|heart rudiment http://purl.obolibrary.org/obo/UBERON_0004139 CHEBI:57953 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alaninate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57953 chebi_ph7_3 UBERON:0004136 biolink:AnatomicalEntity intermediate tubule The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules go-plus.json tubulus attenuatus|renal intermediate tubule http://purl.obolibrary.org/obo/UBERON_0004136 CHEBI:57951 biolink:ChemicalSubstance L-saccharopinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57951 chebi_ph7_3 UBERON:0004134 biolink:AnatomicalEntity proximal tubule In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. go-plus.json kidney proximal tubule|proximal kidney tubule|renal proximal tubule http://purl.obolibrary.org/obo/UBERON_0004134 CHEBI:18340 biolink:ChemicalSubstance cis-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18340 UBERON:0004135 biolink:AnatomicalEntity distal tubule The distal tubule is a nephron tubule that consists of the distal convoluted tubule and distal straight tubule segments go-plus.json renal distal tubule|kidney distal tubule http://purl.obolibrary.org/obo/UBERON_0004135 CHEBI:18341 biolink:ChemicalSubstance diacetylchitobiosyldiphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18341 CHEBI:18383 biolink:ChemicalSubstance 3-aminoalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18383 CHEBI:57949 biolink:ChemicalSubstance 6-phosphonato-5-dehydro-2-deoxy-D-gluconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57949 chebi_ph7_3 CHEBI:82949 biolink:ChemicalSubstance 1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82949 chebi_ph7_3 CHEBI:18380 biolink:ChemicalSubstance 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18380 CHEBI:18381 biolink:ChemicalSubstance 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18381 CHEBI:57947 biolink:ChemicalSubstance creatine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57947 chebi_ph7_3 CHEBI:82947 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3'-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82947 CHEBI:57948 biolink:ChemicalSubstance 5-oxo-D-prolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57948 chebi_ph7_3 CHEBI:82948 biolink:ChemicalSubstance 1,2-dipalmitoylglycero-3-phospho-(1'-D-myo-inositol-3'-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82948 CHEBI:57945 biolink:ChemicalSubstance NADH(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57945 chebi_ph7_3 CHEBI:82945 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82945 chebi_ph7_3 CHEBI:57946 biolink:ChemicalSubstance N-methylphenylethanolaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57946 chebi_ph7_3 CHEBI:82943 biolink:ChemicalSubstance 1-palmitoyl-2-icosanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82943 chebi_ph7_3 CHEBI:33976 biolink:ChemicalSubstance magnesium coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33976 CHEBI:82940 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82940 chebi_ph7_3 UBERON:0004121 biolink:AnatomicalEntity ectoderm-derived structure An anatomical structure that develops (entirely or partially) from the ectoderm. go-plus.json ectodermal deriviative http://purl.obolibrary.org/obo/UBERON_0004121 UBERON:0004122 biolink:AnatomicalEntity genitourinary system Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. go-plus.json urogenital tract|UG tract|genitourinary tract|Urogenitalsystem|genito-urinary system|GU tract|urogenital system http://purl.obolibrary.org/obo/UBERON_0004122 CHEBI:33970 biolink:ChemicalSubstance elemental gold go-plus.json http://purl.obolibrary.org/obo/CHEBI_33970 UBERON:0004120 biolink:AnatomicalEntity mesoderm-derived structure An anatomical structure that develops (entirely or partially) from the mesoderm. go-plus.json mesodermal derivative http://purl.obolibrary.org/obo/UBERON_0004120 CHEBI:33973 biolink:ChemicalSubstance elemental magnesium go-plus.json http://purl.obolibrary.org/obo/CHEBI_33973 CHEBI:18379 biolink:ChemicalSubstance nitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_18379 chebi_ph7_3 UBERON:0004129 biolink:AnatomicalEntity growth plate cartilage cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. go-plus.json growth plate http://purl.obolibrary.org/obo/UBERON_0004129 CHEBI:18377 biolink:ChemicalSubstance N-formylkynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18377 UBERON:0004127 biolink:AnatomicalEntity compact layer of ventricle The outer layer the ventricular myocardium, muscle fibers are arranged in a compact form and involved the entire ventricle. go-plus.json ventricular myocardial compact zone|compact cardiac ventricle muscle|ventricular myocardial compact layer|ventricular compact myocardium|ventricle myocardium compact zone http://purl.obolibrary.org/obo/UBERON_0004127 UBERON:0004128 biolink:AnatomicalEntity optic vesicle The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. go-plus.json optic vesicles|eye vesicle|evagination|ocular vesicle http://purl.obolibrary.org/obo/UBERON_0004128 CHEBI:57942 biolink:ChemicalSubstance chlorophyllide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57942 CHEBI:18378 biolink:ChemicalSubstance 4alpha-methyl-5alpha-cholest-7-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18378 chebi_ph7_3 UBERON:0004125 biolink:AnatomicalEntity myocardial compact layer outer dense layer of the myocardium uniting the epicardium and myocardium[MP]. go-plus.json myocardium compact layer|compact subepicardial myocardium|subepicardium layer|heart compact layer|compact subepicardial layer|subepicardial layer|myocardial compact layer|subepicardium http://purl.obolibrary.org/obo/UBERON_0004125 CHEBI:18375 biolink:ChemicalSubstance nucleoside 3',5'-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18375 CHEBI:18376 biolink:ChemicalSubstance dermatan sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18376 UBERON:0004126 biolink:AnatomicalEntity trabecular layer of ventricle A myocardium trabecular layer that is part of a cardiac ventricle. go-plus.json ventricular trabecular myocardium|trabecular cardiac ventricle muscle|myocardium of region of ventricle http://purl.obolibrary.org/obo/UBERON_0004126 CHEBI:57940 biolink:ChemicalSubstance 3-sulfonatopyruvate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57940 chebi_ph7_3 UBERON:0004123 biolink:AnatomicalEntity myocardial layer Any of the layers of the myocardium. Example: compact layer, trabecular layer. go-plus.json layer of myocardium|myocardium layer http://purl.obolibrary.org/obo/UBERON_0004123 CHEBI:18373 biolink:ChemicalSubstance (7S)-salutaridinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18373 UBERON:0004124 biolink:AnatomicalEntity myocardium trabecular layer The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]. go-plus.json heart muscle trabeculae|myocardial trabeculae carneae|trabecula of heart muscle|trabecular layer|myocardial trabecular layer|trabeculae|heart muscle trabecula http://purl.obolibrary.org/obo/UBERON_0004124 CHEBI:18374 biolink:ChemicalSubstance 1-(5-phospho-beta-D-ribosyl)-5'-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_18374 CHEBI:18371 biolink:ChemicalSubstance cis-4-carboxymethylenebut-2-en-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18371 CHEBI:18372 biolink:ChemicalSubstance 7,8-dihydroneopterin 3'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18372 CHEBI:57938 biolink:ChemicalSubstance trans-3-hydroxy-L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57938 chebi_ph7_3 CHEBI:18370 biolink:ChemicalSubstance 7-deoxyloganin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18370 chebi_ph7_3 CHEBI:57939 biolink:ChemicalSubstance sphinganine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57939 chebi_ph7_3 CHEBI:57936 biolink:ChemicalSubstance N-acetyl-L-gamma-glutamyl phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57936 chebi_ph7_3 CHEBI:82959 biolink:ChemicalSubstance N-hexanoylsphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82959 chebi_ph7_3 CHEBI:57937 biolink:ChemicalSubstance 2-aminomuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57937 CHEBI:57934 biolink:ChemicalSubstance psychosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57934 chebi_ph7_3 CHEBI:82957 biolink:ChemicalSubstance 3-hydroxyisovalerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82957 chebi_ph7_3 CHEBI:57935 biolink:ChemicalSubstance oxidized Watasenia luciferin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57935 chebi_ph7_3 CHEBI:82954 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3',5'-bisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82954 CHEBI:82953 biolink:ChemicalSubstance 1-(3-O-sulfonato-beta-D-galactosyl)ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82953 chebi_ph7_3 CHEBI:82950 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-glycoloylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82950 chebi_ph7_3 CHEBI:82951 biolink:ChemicalSubstance alpha-N-glycoloylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82951 chebi_ph7_3 UBERON:0004111 biolink:AnatomicalEntity anatomical conduit Any tube, opening or passage that connects two distinct anatomical spaces. go-plus.json opening|foramina|ostium|foramen|ostia http://purl.obolibrary.org/obo/UBERON_0004111 CHEBI:33980 biolink:ChemicalSubstance quinovose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33980 CHEBI:33983 biolink:ChemicalSubstance deoxymannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33983 CHEBI:33984 biolink:ChemicalSubstance fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33984 CHEBI:33985 biolink:ChemicalSubstance muramates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33985 CHEBI:33986 biolink:ChemicalSubstance muramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33986 UBERON:0004118 biolink:AnatomicalEntity vasculature of iris A vasculature that is part of a iris [Automatically generated definition]. go-plus.json iris vasculature|vascular network of iris|iris blood vessels|iris vascular network http://purl.obolibrary.org/obo/UBERON_0004118 CHEBI:18368 biolink:ChemicalSubstance D-glucosyl-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18368 chebi_ph7_3 CHEBI:57932 biolink:ChemicalSubstance D-methionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57932 chebi_ph7_3 UBERON:0004119 biolink:AnatomicalEntity endoderm-derived structure An anatomical structure that develops (entirely or partially) from the endoderm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004119 CHEBI:57933 biolink:ChemicalSubstance oleandomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57933 chebi_ph7_3 UBERON:0004116 biolink:AnatomicalEntity nerve of tympanic cavity A nerve that is part of a tympanic cavity [Automatically generated definition]. go-plus.json nerve of middle ear cavity|middle ear cavity nerve|cavity of middle ear nerve|nerve of anatomical cavity of middle ear|nerve of middle ear anatomical cavity|tympanic cavity nerve|anatomical cavity of middle ear nerve|middle ear anatomical cavity nerve|tympanic cavity nerves|nerve of cavity of middle ear http://purl.obolibrary.org/obo/UBERON_0004116 CHEBI:18366 biolink:ChemicalSubstance Arg-tRNA(Arg) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18366 CHEBI:57930 biolink:ChemicalSubstance nucleoside 5'-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57930 chebi_ph7_3 UBERON:0004117 biolink:AnatomicalEntity pharyngeal pouch An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches. go-plus.json visceral pouch|branchial pouch|pharyngeal pouches|visceral pouches http://purl.obolibrary.org/obo/UBERON_0004117 CHEBI:57931 biolink:ChemicalSubstance D-ribofuranosyl-ADP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57931 chebi_ph7_3 CHEBI:18367 biolink:ChemicalSubstance phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18367 UBERON:0004114 biolink:AnatomicalEntity tympanic cavity small cavity surrounding the bones of the middle ear. go-plus.json middle-ear cavity|middle ear cavity|cavity of middle ear|cavitas tympani|tympanum|anatomical cavity of middle ear|cavitas tympanica http://purl.obolibrary.org/obo/UBERON_0004114 CHEBI:18364 biolink:ChemicalSubstance 14-demethyllanosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18364 chebi_ph7_3 UBERON:0004115 biolink:AnatomicalEntity blood vessel of tympanic cavity A blood vessel that is part of a tympanic cavity [Automatically generated definition]. go-plus.json anatomical cavity of middle ear blood vessel|tympanic cavity blood vessel|cavity of middle ear blood vessel|middle ear cavity blood vessel|middle ear blood vessel|blood vessel of cavity of middle ear|blood vessel of middle ear cavity|blood vessel of middle ear anatomical cavity|blood vessel of anatomical cavity of middle ear|middle ear anatomical cavity blood vessel http://purl.obolibrary.org/obo/UBERON_0004115 CHEBI:18365 biolink:ChemicalSubstance naphthalene-1,3,6,8-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18365 chebi_ph7_3 CHEBI:18362 biolink:ChemicalSubstance 17-O-deacetylvindoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_18362 UBERON:0004113 biolink:AnatomicalEntity muscle of auditory ossicle A muscle of the tympanic cavity that attaches to an auditory ossicle. go-plus.json muscle of tympanic cavity|tympanic cavity muscle|muscle of middle ear|ossicular muscle|muscle of auditory ossicles|auditory ossicles muscle http://purl.obolibrary.org/obo/UBERON_0004113 CHEBI:18363 biolink:ChemicalSubstance reticulinylium go-plus.json http://purl.obolibrary.org/obo/CHEBI_18363 chebi_ph7_3 CHEBI:57929 biolink:ChemicalSubstance 7''-O-phosphohygromycin B(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57929 chebi_ph7_3 CHEBI:57927 biolink:ChemicalSubstance oxaloacetate 4-methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_57927 chebi_ph7_3 CHEBI:57928 biolink:ChemicalSubstance 3',4',5-trihydroxy-3-methoxyflavon-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57928 chebi_ph7_3 CHEBI:57925 biolink:ChemicalSubstance glutathionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57925 chebi_ph7_3 CHEBI:57926 biolink:ChemicalSubstance L-threonine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57926 chebi_ph7_3 CHEBI:82967 biolink:ChemicalSubstance (11Z)-3-oxohexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82967 CHEBI:57923 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57923 chebi_ph7_3 CHEBI:57924 biolink:ChemicalSubstance L-dopaquinone zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57924 chebi_ph7_3 CHEBI:33954 biolink:ChemicalSubstance tagatose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33954 UBERON:0004180 biolink:AnatomicalEntity mammary gland fat The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts go-plus.json fat tissue of lactiferous gland|adipose tissue of lactiferous gland|lactiferous gland fatty tissue|lobe of mammary gland adipose tissue|fatty tissue of mammary gland|lobe of mammary gland fat tissue|lobe of breast adipose tissue|fat tissue of mammary gland|fat tissue of lobe of breast|lobe of mammary gland fatty tissue|lobe of breast fat tissue|adipose tissue of mammary gland|fatty tissue of lobe of breast|lobe of breast fatty tissue|mammary gland adipose tissue|fatty tissue of lobe of mammary gland|mammary gland fat tissue|fat tissue of lobe of mammary gland|mammary gland fatty tissue|fatty tissue of lactiferous gland|lactiferous gland adipose tissue|lactiferous gland fat tissue http://purl.obolibrary.org/obo/UBERON_0004180 CHEBI:33956 biolink:ChemicalSubstance ribulose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33956 CHEBI:82963 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82963 CHEBI:33957 biolink:ChemicalSubstance xylulose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33957 CHEBI:82961 biolink:ChemicalSubstance 17beta-estradiol 17-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82961 chebi_ph7_3 CHEBI:33958 biolink:ChemicalSubstance halide salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_33958 UBERON:0004187 biolink:AnatomicalEntity Harderian gland The Harderian gland is an anterior orbital gland usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species[GO]. go-plus.json Harder's gland|glandula palpebra tertia profundus|deep gland of the nictitating membrane|Hardarian gland|gland of Hardarian http://purl.obolibrary.org/obo/UBERON_0004187 UBERON:0004188 biolink:AnatomicalEntity glomerular epithelium The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. go-plus.json glomerular epithelial cell|epithelium of kidney glomerulus|epithelium of glomerulus|epithelium of renal glomerulus|kidney glomerular epithelium http://purl.obolibrary.org/obo/UBERON_0004188 CHEBI:18319 biolink:ChemicalSubstance SAICAR go-plus.json http://purl.obolibrary.org/obo/CHEBI_18319 UBERON:0004185 biolink:AnatomicalEntity endodermal part of digestive tract A portions of the gut that is derived from endoderm. go-plus.json gut endoderm|endodermal gut http://purl.obolibrary.org/obo/UBERON_0004185 UBERON:0004186 biolink:AnatomicalEntity olfactory bulb mitral cell layer The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer go-plus.json mitral cell layer of the olfactory bulb|mitral cell body layer|olfactory bulb main mitral cell body layer|mitral cell layer|OB mitral cell layer http://purl.obolibrary.org/obo/UBERON_0004186 UBERON:0004183 biolink:AnatomicalEntity placental labyrinth blood vessel The embryonic vessels grow through the layer to come in close contact with the maternal blood supply go-plus.json blood vessel of placenta labyrinth|blood vessel of labyrinthine layer|blood vessel of labyrinthine layer of placenta|labyrinthine layer of placenta blood vessel|labyrinthine layer blood vessel|placenta labyrinth blood vessel http://purl.obolibrary.org/obo/UBERON_0004183 CHEBI:18317 biolink:ChemicalSubstance N-acetyl-LL-2,6-diaminopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18317 UBERON:0004184 biolink:AnatomicalEntity prostate gland stroma The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland go-plus.json prostatic stroma|stroma of prostate gland|prostate stroma|stroma of glandular part of prostate|stroma of prostate http://purl.obolibrary.org/obo/UBERON_0004184 CHEBI:18318 biolink:ChemicalSubstance galactosylceramide sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18318 CHEBI:33951 biolink:ChemicalSubstance psicose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33951 CHEBI:33952 biolink:ChemicalSubstance sorbose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33952 CHEBI:18315 biolink:ChemicalSubstance pyrroloquinoline quinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18315 CHEBI:33953 biolink:ChemicalSubstance tagatose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33953 CHEBI:18316 biolink:ChemicalSubstance 4-ethylamino-6-isopropylamino-1,3,5-triazin-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18316 chebi_ph7_3 UBERON:0004182 biolink:AnatomicalEntity mammary gland cord The solid cord of epithelial cells that emerges from the mammary bud and grows down from the primary mammary mesenchyme and into a second stromal compartment, the fat pad precursor, beneath the dermis. go-plus.json lactiferous gland cord|mammary cord|mammary sprout http://purl.obolibrary.org/obo/UBERON_0004182 CHEBI:18313 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18313 chebi_ph7_3 CHEBI:57921 biolink:ChemicalSubstance N(3')-acetyl-2-deoxystreptamine antibiotic(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57921 chebi_ph7_3 PO:0004010 biolink:OntologyClass meristematic cell A native plant cell (PO:0025606) synthesizing protoplasm and producing new cells by division and with only a primary cell wall. go-plus.json célula meristemática (Spanish, exact)|分裂組織細胞 (Japanese, exact)|stem cell (exact) http://purl.obolibrary.org/obo/PO_0004010 CHEBI:57922 biolink:ChemicalSubstance coenzyme gamma-F420-2(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57922 chebi_ph7_3 CHEBI:18314 biolink:ChemicalSubstance L-2-aminopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18314 CHEBI:18311 biolink:ChemicalSubstance quinoline-4-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18311 CHEBI:57920 biolink:ChemicalSubstance bis(3-azaniumylpropyl)azanium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57920 chebi_ph7_3 CHEBI:18312 biolink:ChemicalSubstance 4-(hydroxymethyl)benzenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18312 PO:0004013 biolink:OntologyClass epidermal cell A native plant cell (PO:0025606) that is part of a portion of epidermis (PO:0005679). go-plus.json célula epidérmica (Spanish, exact)|表皮細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0004013 CHEBI:18310 biolink:ChemicalSubstance alkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_18310 chebi_ph7_3 PO:0004011 biolink:OntologyClass initial cell A meristematic cell (PO:0004010) that by division gives rise to two cells, one of which remains meristematic, while the other is added to the plant body. go-plus.json célula inicial (Spanish, exact)|meristemoid (exact)|stem cell (related)|始原細胞 (Japanese, exact)|initial (exact) http://purl.obolibrary.org/obo/PO_0004011 UBERON:0004189 biolink:AnatomicalEntity glomerular endothelium The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus go-plus.json endothelium of renal glomerulus|renal glomerulus endothelium http://purl.obolibrary.org/obo/UBERON_0004189 CHEBI:57918 biolink:ChemicalSubstance alpha-ribazole 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57918 chebi_ph7_3 CHEBI:57919 biolink:ChemicalSubstance 4-CDP-2-C-methyl-D-erythritol 2-phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57919 chebi_ph7_3 CHEBI:57916 biolink:ChemicalSubstance 3-hexaprenyl-4-hydroxy-5-methoxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57916 chebi_ph7_3 CHEBI:57917 biolink:ChemicalSubstance 4-nitrophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57917 chebi_ph7_3 CHEBI:57914 biolink:ChemicalSubstance kievitone-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57914 CHEBI:57915 biolink:ChemicalSubstance L-gamma-glutamyl-D-alaninate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57915 chebi_ph7_3 CHEBI:57912 biolink:ChemicalSubstance L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57912 chebi_ph7_3 CHEBI:67347 biolink:ChemicalSubstance (+)-pisatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_67347 chebi_ph7_3 CHEBI:33966 biolink:ChemicalSubstance elemental silver go-plus.json http://purl.obolibrary.org/obo/CHEBI_33966 CHEBI:33969 biolink:ChemicalSubstance gold molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33969 CHEBI:82972 biolink:ChemicalSubstance 3alpha-hydroxy-3,5-dihydromonacolin L acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82972 CHEBI:82970 biolink:ChemicalSubstance dihydromonacolin L acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82970 CHEBI:82971 biolink:ChemicalSubstance monacolin J acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82971 UBERON:0004176 biolink:AnatomicalEntity external genitalia The external genitalia are the outer sex organs, such as the penis or vulva in mammals go-plus.json external genitalia|external reproductive organ|external sex organ http://purl.obolibrary.org/obo/UBERON_0004176 UBERON:0004177 biolink:AnatomicalEntity hemopoietic organ Organ that is part of the hematopoietic system. go-plus.json hematopoeitic organ|organ of haemopoietic system|lymph organ|lymphoid organ|organ of haematological system|organ of organa haemopoietica|hematopoeitic or lymphoid organ|organ of hematopoietic system|organa haemopoietica organ|haemopoietic system organ|hematopoietic system organ|haematological system organ http://purl.obolibrary.org/obo/UBERON_0004177 CHEBI:18308 biolink:ChemicalSubstance acrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18308 UBERON:0004175 biolink:AnatomicalEntity internal genitalia The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals go-plus.json internal sex organ|internal reproductive organ|internal genitalia|internal genitals http://purl.obolibrary.org/obo/UBERON_0004175 CHEBI:18306 biolink:ChemicalSubstance thiamine(1+) carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18306 UBERON:0004172 biolink:AnatomicalEntity pons reticulospinal tract Axon tract that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004172 CHEBI:18307 biolink:ChemicalSubstance UDP-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18307 UBERON:0004173 biolink:AnatomicalEntity medulla reticulospinal tract Axon tract that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord[GO]. go-plus.json medullary reticulospinal tract http://purl.obolibrary.org/obo/UBERON_0004173 UBERON:0004170 biolink:AnatomicalEntity spinal cord ventral commissure The band of nerve fibers which cross the midline of the spinal cord ventral to the central canal and posterior grey commissure[MP]. The anterior (or ventral) white commissure, also known as the alba anterior medullae spinalis, is a bundle of nerve fibers which cross the midline of the spinal cord just anterior to the gray commissure. A N4 fibers and C fibers carrying pain sensation in the spinothalamic tract contribute to this commissure, as do fibers of the anterior corticospinal tract, which carry motor signals from the primary motor cortex[WP]. go-plus.json anterior white commissure|ventral spinal commissure|ventral white column|spinal cord anterior commissure|anterior white commissure of spinal cord|white commissure|commissura alba anterior medullae spinalis|alba anterior medullae spinalis|ventral commissure of the spinal cord|ventral white commissure of spinal cord|anterior commissure http://purl.obolibrary.org/obo/UBERON_0004170 CHEBI:18304 biolink:ChemicalSubstance deamido-NAD(+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18304 UBERON:0004171 biolink:AnatomicalEntity trigeminothalamic tract The trigeminothalamic tract is one of the major routes of nociceptive and temperature signaling from the face go-plus.json trigeminal tract|tractus trigeminothalamicus http://purl.obolibrary.org/obo/UBERON_0004171 CHEBI:18305 biolink:ChemicalSubstance hydroquinone O-beta-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_18305 chebi_ph7_3 CHEBI:33964 biolink:ChemicalSubstance silver molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33964 CHEBI:18302 biolink:ChemicalSubstance 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18302 CHEBI:18303 biolink:ChemicalSubstance phosphatidyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18303 CHEBI:18300 biolink:ChemicalSubstance maleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18300 CHEBI:18301 biolink:ChemicalSubstance (2Z,4E)-4-hydroxymuconic semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18301 UBERON:0004178 biolink:AnatomicalEntity aorta smooth muscle tissue the nonstriated, involuntary muscle tissue located in the wall of the aorta go-plus.json aortic smooth muscle|aorta non-striated muscle|aorta smooth muscle http://purl.obolibrary.org/obo/UBERON_0004178 UBERON:0004179 biolink:AnatomicalEntity prostate glandular acinus A saclike structure of the prostate gland, comprised of at least three cell layers: an innermost layer of secretory columnar luminal epithelium, a middle layer of squamous basal epithelium that also contains neuroendocrine cells, transit amplifying cells, and stem cells, and an outer layer of smooth muscle intermixed with other stromal cells go-plus.json prostatic acinus|prostatic follicle http://purl.obolibrary.org/obo/UBERON_0004179 CHEBI:57907 biolink:ChemicalSubstance all-trans-pentaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57907 chebi_ph7_3 CHEBI:57908 biolink:ChemicalSubstance N-benzoyl-D-arginine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57908 chebi_ph7_3 CHEBI:57905 biolink:ChemicalSubstance dehydroepiandrosterone sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57905 chebi_ph7_3 CHEBI:57906 biolink:ChemicalSubstance trans-4-hydroxycyclohexanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57906 chebi_ph7_3 CHEBI:57903 biolink:ChemicalSubstance [1-(5-phosphonatoribosyl)imidazol-4-yl]acetate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57903 chebi_ph7_3 CHEBI:57904 biolink:ChemicalSubstance D-glucose 6-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57904 chebi_ph7_3 CHEBI:57901 biolink:ChemicalSubstance L-threo-3-phenylserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57901 chebi_ph7_3 CHEBI:57902 biolink:ChemicalSubstance 1-benzyl-1,2,3,4-tetrahydroisoquinolin-2-ium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57902 chebi_ph7_3 CHEBI:82987 biolink:ChemicalSubstance monacolin L acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82987 CHEBI:82985 biolink:ChemicalSubstance mevinolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82985 CHEBI:82983 biolink:ChemicalSubstance 1-oleoyl-2-acyl-sn-3-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82983 chebi_ph7_3 CHEBI:33937 biolink:ChemicalSubstance macronutrient go-plus.json http://purl.obolibrary.org/obo/CHEBI_33937 CHEBI:57909 biolink:ChemicalSubstance kanamycin A 3'-phosphate(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57909 chebi_ph7_3 CHEBI:82982 biolink:ChemicalSubstance glycodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82982 chebi_ph7_3 UBERON:0004166 biolink:AnatomicalEntity superior reticular formation . go-plus.json http://purl.obolibrary.org/obo/UBERON_0004166 UBERON:0004164 biolink:AnatomicalEntity branchiomeric muscle A jaw muscle that arises from cranial mesenchyme and is innervated by cranial nerves. go-plus.json branchiomeric skeletal muscle|branchial head muscle http://purl.obolibrary.org/obo/UBERON_0004164 UBERON:0004161 biolink:AnatomicalEntity septum transversum A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. go-plus.json transverse septum http://purl.obolibrary.org/obo/UBERON_0004161 UBERON:0004162 biolink:AnatomicalEntity pulmonary myocardium The pulmonary myocardium is the myocardial tissue present in the pulmonary vein go-plus.json http://purl.obolibrary.org/obo/UBERON_0004162 CHEBI:18337 biolink:ChemicalSubstance 5-amino-6-(5-phospho-beta-D-ribosylamino)uracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_18337 UBERON:0004160 biolink:AnatomicalEntity proepicardium An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium go-plus.json proepicardial cluster|proepicardial organ http://purl.obolibrary.org/obo/UBERON_0004160 NCBITaxon:6102 biolink:OrganismalEntity Hexacorallia go-plus.json Zoantharia http://purl.obolibrary.org/obo/NCBITaxon_6102 CHEBI:18335 biolink:ChemicalSubstance pyridoxamine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18335 NCBITaxon:6103 biolink:OrganismalEntity Actiniaria go-plus.json actinians|sea anemones|sea anemones http://purl.obolibrary.org/obo/NCBITaxon_6103 CHEBI:18336 biolink:ChemicalSubstance 4-(phosphonooxy)-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18336 CHEBI:57900 biolink:ChemicalSubstance oxidized Photinus luciferin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57900 CHEBI:18333 biolink:ChemicalSubstance D-arabinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18333 chebi_ph7_3 CHEBI:18334 biolink:ChemicalSubstance adenosine 5'-(pentahydrogen tetraphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18334 NCBITaxon:6101 biolink:OrganismalEntity Anthozoa go-plus.json anthozoans|anthozoans http://purl.obolibrary.org/obo/NCBITaxon_6101 CHEBI:18332 biolink:ChemicalSubstance L-thyroxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18332 UBERON:0004167 biolink:AnatomicalEntity orbitofrontal cortex The region of the cerebral cortex covering the basal surface of the frontal lobes; this region normally controls emotion and decision making go-plus.json orbital frontal cortex|orbito-frontal cortex|segment of cortex of frontal lobe|fronto-orbital cortex http://purl.obolibrary.org/obo/UBERON_0004167 CHEBI:18330 biolink:ChemicalSubstance isovitexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18330 CHEBI:33946 biolink:ChemicalSubstance erythrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33946 CHEBI:33947 biolink:ChemicalSubstance threose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33947 CHEBI:33949 biolink:ChemicalSubstance ketoheptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33949 UBERON:0004154 biolink:AnatomicalEntity atrial septum primum In the developing heart, the cavity of the primitive atrium becomes subdivided into right and left chambers by a septum, the septum primum, which grows downward into the cavity. The increasingly smaller gap below it (before it fuses with the endocardial cushion) is known as the ostium primum. The septum primum eventually fuses with the endocardial cushion, closing the ostium primum off completely. Meanwhile, perforations appear in the superior part of the septum primum, forming the ostium secundum. This will eventually form part of the fossa ovalis. go-plus.json septum primum|atrial septum primum|interatrial septum primum http://purl.obolibrary.org/obo/UBERON_0004154 UBERON:0004155 biolink:AnatomicalEntity atrial septum secundum . go-plus.json septum secundum|interatrial septum secundum http://purl.obolibrary.org/obo/UBERON_0004155 UBERON:0004152 biolink:AnatomicalEntity bulbus arteriosus The bulbus arteriosus is an elastic heart chamber[GO]. Multi-tissue structure that consists of three layers and through which the blood exits the heart. The bulbus arteriosus is a pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches[ZFA]. go-plus.json truncus http://purl.obolibrary.org/obo/UBERON_0004152 UBERON:0004153 biolink:AnatomicalEntity ventricular septum intermedium Endocardial cushions project into the atrial canal, and, meeting in the middle line, unite to form the septum intermedium which divides the canal into two channels, the future right and left atrioventricular orifices[Gray's via WP]. go-plus.json septum intermedium http://purl.obolibrary.org/obo/UBERON_0004153 UBERON:0004150 biolink:AnatomicalEntity coronary sinus valve Vestigial cardiac valve which is continuous with the valve of the inferior vena cava[FMA]. go-plus.json thebesian valve|thebesius valve|valve of coronary sinus http://purl.obolibrary.org/obo/UBERON_0004150 CHEBI:18328 biolink:ChemicalSubstance 13-hydroxylupanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18328 CHEBI:18329 biolink:ChemicalSubstance 5alpha-androstane-3beta,17beta-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18329 chebi_ph7_3 UBERON:0004151 biolink:AnatomicalEntity cardiac chamber A cardiac chamber surrounds an enclosed cavity within the heart go-plus.json heart chamber|chamber of heart http://purl.obolibrary.org/obo/UBERON_0004151 CHEBI:33942 biolink:ChemicalSubstance ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33942 CHEBI:18327 biolink:ChemicalSubstance N-formimidoyl-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18327 CHEBI:18325 biolink:ChemicalSubstance 2-succinatobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18325 chebi_ph7_3 CHEBI:18322 biolink:ChemicalSubstance 6-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18322 chebi_ph7_3 CHEBI:18323 biolink:ChemicalSubstance anserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18323 CHEBI:18320 biolink:ChemicalSubstance 1,4-dithiothreitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18320 chebi_ph7_3 UBERON:0004159 biolink:AnatomicalEntity atrial septum intermedium . go-plus.json http://purl.obolibrary.org/obo/UBERON_0004159 CHEBI:18321 biolink:ChemicalSubstance 1-(sn-glycero-3-phospho)-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18321 GO:0005338 biolink:MolecularActivity nucleotide-sugar transmembrane transporter activity Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. Reactome:R-HSA-744231|Reactome:R-HSA-744230 go-plus.json http://purl.obolibrary.org/obo/GO_0005338 GO:0005339 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005339 GO:0005336 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005336 GO:0005337 biolink:MolecularActivity nucleoside transmembrane transporter activity Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other. RHEA:27318|Reactome:R-HSA-109529|Reactome:R-HSA-727740|Reactome:R-HSA-109534|Reactome:R-HSA-5628807|Reactome:R-HSA-727768|Reactome:R-HSA-109527|Reactome:R-HSA-727749|Reactome:R-HSA-109536|Reactome:R-HSA-727767 go-plus.json intracellular nucleoside transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005337 GO:0005334 biolink:MolecularActivity norepinephrine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in). Reactome:R-HSA-5659764|Reactome:R-HSA-443997|Wikipedia:Norepinephrine_transporter go-plus.json noradrenaline transporter activity|norepinephrine:sodium:chloride symporter activity|levarterenol transporter activity|sodium/norepinephrine symporter activity|norepinephrine transmembrane transporter activity|norepinephrine:sodium symporter activity http://purl.obolibrary.org/obo/GO_0005334 NCBITaxon:6159 biolink:OrganismalEntity Tricladida go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6159 GO:0005335 biolink:MolecularActivity serotonin:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in). RHEA:51196|Reactome:R-HSA-444008 go-plus.json serotonin:sodium:chloride symporter activity|sodium/serotonin symporter activity|serotonin transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005335 GO:0005332 biolink:MolecularActivity gamma-aminobutyric acid:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in). Reactome:R-HSA-444007 go-plus.json 4-aminobutyrate:sodium symporter activity|GABA:sodium symporter activity|betaine/GABA:sodium symporter activity|sodium/chloride-dependent GABA transporter activity|4-aminobutanoate:sodium symporter activity http://purl.obolibrary.org/obo/GO_0005332 GO:0005333 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005333 GO:0005330 biolink:MolecularActivity dopamine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in). go-plus.json dopamine:sodium:chloride symporter activity|sodium/dopamine symporter activity|dopamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005330 GO:0005331 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005331 GO:0019979 biolink:MolecularActivity interleukin-4 binding Binding to interleukin-4. go-plus.json IL-4 binding http://purl.obolibrary.org/obo/GO_0019979 GO:0019977 biolink:MolecularActivity interleukin-21 binding Binding to interleukin-21. go-plus.json IL-21 binding http://purl.obolibrary.org/obo/GO_0019977 GO:0019978 biolink:MolecularActivity interleukin-3 binding Binding to interleukin-3. go-plus.json IL-3 binding http://purl.obolibrary.org/obo/GO_0019978 GO:0019975 biolink:MolecularActivity interleukin-17 binding Binding to a member of the interleukin-17 family of cytokines. go-plus.json IL-17 binding http://purl.obolibrary.org/obo/GO_0019975 GO:0019976 biolink:MolecularActivity interleukin-2 binding Binding to interleukin-2. go-plus.json IL-2 binding http://purl.obolibrary.org/obo/GO_0019976 GO:0019973 biolink:MolecularActivity interleukin-13 binding Binding to interleukin-13. go-plus.json IL-13 binding http://purl.obolibrary.org/obo/GO_0019973 GO:0019974 biolink:MolecularActivity interleukin-14 binding Binding to interleukin-14. go-plus.json IL-14 binding http://purl.obolibrary.org/obo/GO_0019974 GO:0019972 biolink:MolecularActivity interleukin-12 binding Binding to interleukin-12. go-plus.json IL-12 binding http://purl.obolibrary.org/obo/GO_0019972 GO:0019970 biolink:MolecularActivity interleukin-11 binding Binding to interleukin-11. go-plus.json IL-11 binding http://purl.obolibrary.org/obo/GO_0019970 GO:0005349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005349 GO:0005347 biolink:MolecularActivity ATP transmembrane transporter activity Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0005347 GO:0005348 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005348 GO:0005345 biolink:MolecularActivity purine nucleobase transmembrane transporter activity Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other. go-plus.json purine base transmembrane transporter activity|purine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005345 CHEBI:149759 biolink:ChemicalSubstance 2-methyl-L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_149759 chebi_ph7_3 GO:0005346 biolink:MolecularActivity purine ribonucleotide transmembrane transporter activity Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0005346 GO:0005343 biolink:MolecularActivity organic acid:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in). Reactome:R-HSA-8876312 go-plus.json sodium/chloride-dependent organic acid cotransporter activity|sodium:dicarboxylate/tricarboxylate symporter activity http://purl.obolibrary.org/obo/GO_0005343 GO:0005344 biolink:MolecularActivity oxygen carrier activity Binding to oxygen and delivering it to an acceptor molecule or a specific location. go-plus.json oxygen-carrying|hemerythrin|hemocyanin|globin http://purl.obolibrary.org/obo/GO_0005344 GO:0005341 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005341 GO:0005342 biolink:MolecularActivity organic acid transmembrane transporter activity Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0005342 GO:0005340 biolink:MolecularActivity nucleotide-sulfate transmembrane transporter activity Enables the transfer of nucleotide-sulfate from one side of a membrane to the other. go-plus.json nucleotide-sulphate transporter activity http://purl.obolibrary.org/obo/GO_0005340 GO:0019988 biolink:BiologicalProcess charged-tRNA amino acid modification The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine. go-plus.json pre-translational amino acid modification|pretranslation protein modification|charged-tRNA modification|pre-translational protein modification|charged tRNA amino acid modification|charged tRNA modification|pretranslational amino acid modification http://purl.obolibrary.org/obo/GO_0019988 GO:0019986 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019986 GO:0019987 biolink:BiologicalProcess obsolete negative regulation of anti-apoptosis OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of anti-apoptosis. go-plus.json negative regulation of anti-apoptosis|down-regulation of anti-apoptosis|downregulation of anti-apoptosis|down regulation of anti-apoptosis|inhibition of anti-apoptosis http://purl.obolibrary.org/obo/GO_0019987 GO:0019984 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019984 GO:0019985 biolink:BiologicalProcess translesion synthesis The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. go-plus.json bypass DNA synthesis http://purl.obolibrary.org/obo/GO_0019985 GO:0019982 biolink:MolecularActivity interleukin-7 binding Binding to interleukin-7. go-plus.json IL-7 binding http://purl.obolibrary.org/obo/GO_0019982 GO:0019983 biolink:MolecularActivity interleukin-9 binding Binding to interleukin-9. go-plus.json IL-9 binding http://purl.obolibrary.org/obo/GO_0019983 GO:0019980 biolink:MolecularActivity interleukin-5 binding Binding to interleukin-5. go-plus.json IL-5 binding http://purl.obolibrary.org/obo/GO_0019980 GO:0019981 biolink:MolecularActivity interleukin-6 binding Binding to interleukin-6. go-plus.json IL-6 binding http://purl.obolibrary.org/obo/GO_0019981 GO:0005318 biolink:MolecularActivity obsolete phosphate:hydrogen symporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json phosphate:hydrogen symporter|phosphate:proton symporter activity http://purl.obolibrary.org/obo/GO_0005318 GO:0005319 biolink:MolecularActivity lipid transporter activity Enables the directed movement of lipids into, out of or within a cell, or between cells. Reactome:R-HSA-8848053|Reactome:R-HSA-8866329|Reactome:R-HSA-5683714|Reactome:R-HSA-5682285|Reactome:R-HSA-6801250|Reactome:R-HSA-174786|Reactome:R-HSA-5683672|Reactome:R-HSA-1369028|Reactome:R-HSA-5688397|Reactome:R-HSA-5682311|Reactome:R-HSA-1369052 go-plus.json apolipoprotein|lipophorin http://purl.obolibrary.org/obo/GO_0005319 GO:0005316 biolink:MolecularActivity high-affinity inorganic phosphate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json sodium/phosphate cotransporter activity|high affinity inorganic phosphate:sodium symporter activity http://purl.obolibrary.org/obo/GO_0005316 CHEBI:149743 biolink:ChemicalSubstance N-(fatty acyl)-L-glutamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149743 chebi_ph7_3 GO:0005317 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005317 GO:0005314 biolink:MolecularActivity high-affinity glutamate transmembrane transporter activity Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Reactome:R-HSA-5625015|Reactome:R-HSA-5625029|Reactome:R-HSA-428015|Reactome:R-HSA-210404 go-plus.json high-affinity glutamate transporter activity http://purl.obolibrary.org/obo/GO_0005314 GO:0005315 biolink:MolecularActivity inorganic phosphate transmembrane transporter activity Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json http://purl.obolibrary.org/obo/GO_0005315 GO:0005312 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005312 GO:0005313 biolink:MolecularActivity L-glutamate transmembrane transporter activity Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid. Reactome:R-HSA-5624256|Reactome:R-HSA-210444|Reactome:R-HSA-428052 go-plus.json glutamate/aspartate:sodium symporter activity|L-glutamate transporter activity|glutamate/aspartate porter activity http://purl.obolibrary.org/obo/GO_0005313 GO:0005310 biolink:MolecularActivity dicarboxylic acid transmembrane transporter activity Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups. Reactome:R-HSA-1614546|Reactome:R-HSA-372843 go-plus.json dicarboxylate (succinate/fumarate/malate) antiporter activity|dicarboxylic acid permease activity|dicarboxylate carrier|sodium:dicarboxylate/tricarboxylate symporter activity http://purl.obolibrary.org/obo/GO_0005310 GO:0005311 biolink:MolecularActivity obsolete sodium:dicarboxylate/tricarboxylate symporter activity OBSOLETE. Catalysis of the reaction: (dicarboxylate or tricarboxylate)(out) + Na+(out) = (dicarboxylate or tricarboxylate)(in) + Na+(in). go-plus.json sodium:dicarboxylate/tricarboxylate symporter activity|sodium:dicarboxylate/tricarboxylate cotransporter activity http://purl.obolibrary.org/obo/GO_0005311 CHEBI:149741 biolink:ChemicalSubstance N-(fatty acyl)-L-isoleucine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149741 chebi_ph7_3 CHEBI:149742 biolink:ChemicalSubstance N-(fatty acyl)-glycine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149742 chebi_ph7_3 CHEBI:149740 biolink:ChemicalSubstance N-(fatty acyl)-L-leucine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149740 chebi_ph7_3 GO:0019959 biolink:MolecularActivity interleukin-8 binding Binding to interleukin-8. go-plus.json IL-8 binding http://purl.obolibrary.org/obo/GO_0019959 GO:0019957 biolink:MolecularActivity C-C chemokine binding Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif. go-plus.json http://purl.obolibrary.org/obo/GO_0019957 GO:0019958 biolink:MolecularActivity C-X-C chemokine binding Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif. go-plus.json http://purl.obolibrary.org/obo/GO_0019958 GO:0019955 biolink:MolecularActivity cytokine binding Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. go-plus.json interleukin binding|IL binding http://purl.obolibrary.org/obo/GO_0019955 GO:0019956 biolink:MolecularActivity chemokine binding Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0019956 GO:0019953 biolink:BiologicalProcess sexual reproduction A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny. Wikipedia:Sexual_reproduction go-plus.json http://purl.obolibrary.org/obo/GO_0019953 GO:0019954 biolink:BiologicalProcess asexual reproduction The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process. Wikipedia:Asexual_reproduction go-plus.json parthenogenesis http://purl.obolibrary.org/obo/GO_0019954 GO:0019951 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019951 GO:0019952 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019952 GO:0019950 biolink:BiologicalProcess obsolete SMT3-dependent protein catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein. go-plus.json SMT3-dependent protein catabolism|SMT3-dependent protein degradation|SMT3-dependent protein breakdown http://purl.obolibrary.org/obo/GO_0019950 GO:0005329 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005329 GO:0005328 biolink:MolecularActivity neurotransmitter:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in). go-plus.json sodium/neurotransmitter symporter activity http://purl.obolibrary.org/obo/GO_0005328 GO:0005325 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005325 GO:0005326 biolink:MolecularActivity neurotransmitter transmembrane transporter activity Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. Reactome:R-HSA-374896|Reactome:R-HSA-374919 go-plus.json neurotransmitter transporter activity|neurotransmitter transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005326 GO:0005323 biolink:MolecularActivity obsolete very-low-density lipoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json very-low-density lipoprotein|VLDL http://purl.obolibrary.org/obo/GO_0005323 GO:0005324 biolink:MolecularActivity long-chain fatty acid transporter activity Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. Reactome:R-HSA-2046093|Reactome:R-HSA-5684043|Reactome:R-HSA-2046087|Reactome:R-HSA-390393|Reactome:R-HSA-434381|Reactome:R-HSA-382575 go-plus.json http://purl.obolibrary.org/obo/GO_0005324 CHEBI:149737 biolink:ChemicalSubstance N-(fatty acyl)-L-methionine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149737 chebi_ph7_3 GO:0005321 biolink:MolecularActivity obsolete high-density lipoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json HDL|high-density lipoprotein http://purl.obolibrary.org/obo/GO_0005321 GO:0005322 biolink:MolecularActivity obsolete low-density lipoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json low-density lipoprotein|LDL http://purl.obolibrary.org/obo/GO_0005322 GO:0005320 biolink:MolecularActivity obsolete apolipoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json apolipoprotein http://purl.obolibrary.org/obo/GO_0005320 GO:0019968 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019968 GO:0019969 biolink:MolecularActivity interleukin-10 binding Binding to interleukin-10. go-plus.json IL-10 binding http://purl.obolibrary.org/obo/GO_0019969 GO:0019966 biolink:MolecularActivity interleukin-1 binding Binding to interleukin-1. go-plus.json IL-1 binding http://purl.obolibrary.org/obo/GO_0019966 GO:0019967 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019967 GO:0019964 biolink:MolecularActivity interferon-gamma binding Binding to interferon-gamma. Interferon gamma is the only member of the type II interferon found so far. go-plus.json IFN-gamma binding|type II interferon binding|IFNG binding http://purl.obolibrary.org/obo/GO_0019964 GO:0019965 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019965 GO:0019962 biolink:MolecularActivity type I interferon binding Binding to a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families. go-plus.json interferon-delta binding|interferon-alpha/beta binding|interferon-kappa binding|interferon-epsilon binding|interferon-tau binding|interferon-zeta binding|type I IFN binding|interferon-omega binding|interferon-alpha binding|interferon-beta binding http://purl.obolibrary.org/obo/GO_0019962 NCBITaxon:6157 biolink:OrganismalEntity Platyhelminthes go-plus.json flatworm|flatworms|flatworms http://purl.obolibrary.org/obo/NCBITaxon_6157 GO:0019963 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019963 GO:0019960 biolink:MolecularActivity C-X3-C chemokine binding Binding to a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif. go-plus.json http://purl.obolibrary.org/obo/GO_0019960 GO:0019961 biolink:MolecularActivity interferon binding Binding to an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent. go-plus.json IFN binding http://purl.obolibrary.org/obo/GO_0019961 GO:0019939 biolink:BiologicalProcess peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically. RESID:AA0308 go-plus.json peptidyl-S-palmitoleyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine synthesis from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0019939 GO:0019937 biolink:BiologicalProcess protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid. RESID:AA0294 go-plus.json http://purl.obolibrary.org/obo/GO_0019937 GO:0019938 biolink:BiologicalProcess peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions. RESID:AA0294 go-plus.json http://purl.obolibrary.org/obo/GO_0019938 GO:0019935 biolink:BiologicalProcess cyclic-nucleotide-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell. go-plus.json cyclic-nucleotide-mediated signalling http://purl.obolibrary.org/obo/GO_0019935 GO:0019936 biolink:BiologicalProcess obsolete inositol phospholipid-mediated signaling OBSOLETE. (Was not defined before being made obsolete). go-plus.json inositol phospholipid-mediated signalling|inositol phospholipid-mediated signaling http://purl.obolibrary.org/obo/GO_0019936 GO:0019933 biolink:BiologicalProcess cAMP-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell. go-plus.json 3',5'-cAMP-mediated signalling|adenosine 3',5'-cyclophosphate-mediated signalling|cAMP-mediated signalling|cyclic AMP-mediated signalling|3',5' cAMP-mediated signaling|cAMP signalling|cAMP signaling|3',5' cAMP-mediated signalling|cyclic AMP-mediated signaling|adenosine 3',5'-cyclophosphate-mediated signaling|3',5'-cAMP-mediated signaling|cAMP-mediated signal transduction http://purl.obolibrary.org/obo/GO_0019933 GO:0019934 biolink:BiologicalProcess cGMP-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell. go-plus.json cGMP-mediated signalling http://purl.obolibrary.org/obo/GO_0019934 GO:0019931 biolink:BiologicalProcess protein-chromophore linkage via peptidyl-N6-3-dehydroretinal-L-lysine The modification of peptidyl-lysine to form N6-3,4-didehydroretinylidene-L-lysine. RESID:AA0312 go-plus.json http://purl.obolibrary.org/obo/GO_0019931 CHEBI:5768 biolink:ChemicalSubstance (1E,4E,8E)-alpha-humulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_5768 chebi_ph7_3 GO:0019932 biolink:BiologicalProcess second-messenger-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell. go-plus.json second messenger mediated signaling|second-messenger-mediated signalling|second messenger mediated signalling|second messenger-mediated signaling|second-messenger-mediated signal transduction|second messenger-mediated signalling http://purl.obolibrary.org/obo/GO_0019932 GO:0019930 biolink:BiologicalProcess cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1. RESID:AA0316 go-plus.json cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester anabolism from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester synthesis from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester formation from peptidyl-aspartic acid http://purl.obolibrary.org/obo/GO_0019930 CHEBI:18399 biolink:ChemicalSubstance codeinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18399 UBERON:0004103 biolink:AnatomicalEntity alveolar ridge one of the two jaw ridges either on the roof of the mouth between the upper teeth and the hard palate or on the bottom of the mouth behind the lower teeth[WP]. The alveolar ridges contain the sockets (alveoli) of the teeth[HP]. go-plus.json margo alveolaris|alveolar margin|alveolar bone|alveolar body|alveolar process http://purl.obolibrary.org/obo/UBERON_0004103 CHEBI:18397 biolink:ChemicalSubstance 2-phenylethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18397 CHEBI:18398 biolink:ChemicalSubstance linear maltodextrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18398 chebi_ph7_3 CHEBI:18396 biolink:ChemicalSubstance beta-D-mannosyldiacetylchitobiosyldiphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18396 GO:0005307 biolink:MolecularActivity choline:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in). go-plus.json sodium/choline symporter activity http://purl.obolibrary.org/obo/GO_0005307 CHEBI:18393 biolink:ChemicalSubstance naphthalene-1,3,8-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18393 chebi_ph7_3 GO:0005308 biolink:MolecularActivity creatine transmembrane transporter activity Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0005308 CHEBI:18394 biolink:ChemicalSubstance 6-O-alpha-D-glucopyranosyl-D-fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18394 chebi_ph7_3 CHEBI:18391 biolink:ChemicalSubstance D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18391 chebi_ph7_3 GO:0005306 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005306 CHEBI:18392 biolink:ChemicalSubstance bis(beta-glucosyluronic acid)bilirubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18392 GO:0005304 biolink:MolecularActivity L-valine transmembrane transporter activity Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid. go-plus.json leucine/valine/isoleucine permease activity|valine/tyrosine/tryptophan permease activity|L-valine transporter activity|leucine/isoleucine/valine porter activity|isoleucine/valine:sodium symporter activity http://purl.obolibrary.org/obo/GO_0005304 CHEBI:18390 biolink:ChemicalSubstance N-acyl-beta-D-galactosylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18390 chebi_ph7_3 CHEBI:149714 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-glucosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149714 chebi_ph7_3 GO:0005301 biolink:MolecularActivity obsolete valine/tyrosine/tryptophan permease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json valine/tyrosine/tryptophan permease activity|hydrogen/valine-tyrosine-tryptophan transporter http://purl.obolibrary.org/obo/GO_0005301 GO:0005302 biolink:MolecularActivity L-tyrosine transmembrane transporter activity Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid. go-plus.json L-tyrosine permease activity|L-tyrosine transporter activity|valine/tyrosine/tryptophan permease activity http://purl.obolibrary.org/obo/GO_0005302 GO:0005300 biolink:MolecularActivity high-affinity tryptophan transmembrane transporter activity Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high-affinity tryptophan transporter activity http://purl.obolibrary.org/obo/GO_0005300 CHEBI:57990 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57990 chebi_ph7_3 GO:0019948 biolink:MolecularActivity SUMO activating enzyme activity Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond. Reactome:R-HSA-2993784|Reactome:R-HSA-2993781|Reactome:R-HSA-2990833 go-plus.json SMT3 activating enzyme|SUMO E1 activator enzyme http://purl.obolibrary.org/obo/GO_0019948 GO:0019949 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019949 CHEBI:57991 biolink:ChemicalSubstance biliverdin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57991 chebi_ph7_3 GO:0019946 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019946 GO:0019947 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019947 GO:0019944 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019944 GO:0019945 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019945 GO:0019942 biolink:BiologicalProcess obsolete NEDD8 class-dependent protein catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to the target protein. go-plus.json NEDD8 class-dependent protein degradation|NEDD8 class-dependent protein breakdown|RUB1-dependent protein degradation|NEDD8 class-dependent protein catabolic process|RUB1-dependent protein catabolism|RUB1-dependent protein catabolic process|NEDD8 class-dependent protein catabolism http://purl.obolibrary.org/obo/GO_0019942 GO:0019943 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019943 GO:0019940 biolink:BiologicalProcess obsolete SUMO-dependent protein catabolic process OBSOLETE. (Was not defined before being made obsolete). go-plus.json SUMO-dependent protein degradation|SUMO-dependent protein breakdown|SUMO-dependent protein catabolic process|SUMO-dependent protein catabolism http://purl.obolibrary.org/obo/GO_0019940 CHEBI:57998 biolink:ChemicalSubstance 3-phosphoglycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57998 chebi_ph7_3 GO:0019941 biolink:BiologicalProcess modification-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein. go-plus.json modification-initiated protein catabolic process|modification-dependent protein breakdown|modification-initiated proteolysis|protein-ligand-dependent protein catabolic process|protein degradation tagging activity|modification-initiated protein catabolism|protein-ligand-dependent protein catabolism|modification-dependent proteolysis|modification-dependent protein catabolism|modification-dependent protein degradation http://purl.obolibrary.org/obo/GO_0019941 CHEBI:57999 biolink:ChemicalSubstance 1-carboxylatovinyl carboxylatophosphonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57999 chebi_ph7_3 CHEBI:18388 biolink:ChemicalSubstance apigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18388 CHEBI:57996 biolink:ChemicalSubstance nororientalinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57996 chebi_ph7_3 CHEBI:57997 biolink:ChemicalSubstance 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57997 chebi_ph7_3 CHEBI:18386 biolink:ChemicalSubstance quinaldic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18386 CHEBI:57994 biolink:ChemicalSubstance 2,3,5,6-tetrachlorobenzene-1,4-bis(olate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57994 chebi_ph7_3 CHEBI:57995 biolink:ChemicalSubstance all-trans-undecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57995 chebi_ph7_3 CHEBI:18387 biolink:ChemicalSubstance N-formimidoyl-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18387 GO:0005309 biolink:MolecularActivity creatine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in). Reactome:R-HSA-200396 go-plus.json sodium/chloride-dependent creatine transporter http://purl.obolibrary.org/obo/GO_0005309 CHEBI:18384 biolink:ChemicalSubstance 1D-myo-inositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18384 CHEBI:57992 biolink:ChemicalSubstance 2-(carboxylatomethoxy)succinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57992 chebi_ph7_3 CHEBI:57993 biolink:ChemicalSubstance (S)-N-methylcoclaurinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57993 chebi_ph7_3 CHEBI:18385 biolink:ChemicalSubstance thiamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18385 chebi_ph7_3 CHEBI:82904 biolink:ChemicalSubstance 2-aminophenylglyoxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82904 chebi_ph7_3 CHEBI:57989 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-galactonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57989 chebi_ph7_3 GO:0019919 biolink:BiologicalProcess peptidyl-arginine methylation, to asymmetrical-dimethyl arginine The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine. RESID:AA0069|RESID:AA0068 go-plus.json peptidyl-arginine methylation, to unsymmetrical-dimethyl arginine http://purl.obolibrary.org/obo/GO_0019919 GO:0019917 biolink:BiologicalProcess peptidyl-D-alanine racemization via peptidyl-L-serine The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine. RESID:AA0191 go-plus.json http://purl.obolibrary.org/obo/GO_0019917 GO:0019918 biolink:BiologicalProcess peptidyl-arginine methylation, to symmetrical-dimethyl arginine The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine. RESID:AA0069|RESID:AA0067 go-plus.json http://purl.obolibrary.org/obo/GO_0019918 GO:0019915 biolink:BiologicalProcess lipid storage The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. go-plus.json storage of lipids|lipid sequestering|sequestering of lipids|sequestration of lipid|lipid retention|retention of lipids|lipid sequestration|sequestration of lipids http://purl.obolibrary.org/obo/GO_0019915 GO:0019916 biolink:BiologicalProcess peptidyl-D-alanine racemization, direct The racemization of peptidyl-alanine. RESID:AA0191 go-plus.json http://purl.obolibrary.org/obo/GO_0019916 CHEBI:57980 biolink:ChemicalSubstance L-histidinol phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57980 chebi_ph7_3 GO:0019913 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019913 GO:0019914 biolink:MolecularActivity cyclin-dependent protein kinase activating kinase regulator activity Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase. EC:2.7.1.- go-plus.json cyclin-dependent protein kinase activating kinase, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0019914 PATO:0002487 biolink:OntologyClass single organismal process quality A quality inhering in a process by virtue of that process having exactly one organism as a participant. go-plus.json http://purl.obolibrary.org/obo/PATO_0002487 GO:0019911 biolink:MolecularActivity structural constituent of myelin sheath The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0019911 GO:0019912 biolink:MolecularActivity cyclin-dependent protein kinase activating kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK). go-plus.json cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity|cdk-activating kinase activity|CAK http://purl.obolibrary.org/obo/GO_0019912 GO:0019910 biolink:CellularComponent mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0019910 PATO:0002486 biolink:OntologyClass multi-organismal process quality A quality inhering in a process by virtue of that process having two or more organisms as participants. go-plus.json http://purl.obolibrary.org/obo/PATO_0002486 CHEBI:57987 biolink:ChemicalSubstance 2-hydroxyadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57987 chebi_ph7_3 CHEBI:57988 biolink:ChemicalSubstance allysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57988 chebi_ph7_3 CHEBI:57985 biolink:ChemicalSubstance S-inosyl-L-homocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57985 chebi_ph7_3 CHEBI:57986 biolink:ChemicalSubstance riboflavin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57986 chebi_ph7_3 CHEBI:57984 biolink:ChemicalSubstance GDP-L-fucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57984 chebi_ph7_3 CHEBI:57981 biolink:ChemicalSubstance D-phenylalanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57981 chebi_ph7_3 CHEBI:57982 biolink:ChemicalSubstance 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57982 chebi_ph7_3 CHEBI:82918 biolink:ChemicalSubstance hexosyl-(1<->1')-N-acylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82918 chebi_ph7_3 CHEBI:82919 biolink:ChemicalSubstance beta-D-glucosyl-(1<->1')-N-acylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82919 chebi_ph7_3 CHEBI:57978 biolink:ChemicalSubstance 2-hydroxy-3-oxopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57978 chebi_ph7_3 CHEBI:57979 biolink:ChemicalSubstance 2-(carboxylatomethyl)-5-oxo-2,5-dihydro-2-furoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57979 chebi_ph7_3 FAO:0001030 biolink:OntologyClass substrate mycelium An invasive mycelium that forms within a solid or semi-solid substrate such as wood, soil or agar. go-plus.json http://purl.obolibrary.org/obo/FAO_0001030 FAO:0001031 biolink:OntologyClass aerial mycelium A mycelium that forms prior to sporulation and extends aerially, or perpendicular, to its substrate. go-plus.json http://purl.obolibrary.org/obo/FAO_0001031 GO:0019928 biolink:BiologicalProcess peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid. RESID:AA0314 go-plus.json http://purl.obolibrary.org/obo/GO_0019928 GO:0019929 biolink:BiologicalProcess peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid. RESID:AA0315 go-plus.json http://purl.obolibrary.org/obo/GO_0019929 GO:0019926 biolink:BiologicalProcess peptidyl-tryptophan oxidation to tryptophyl quinone The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0019926 GO:0019927 biolink:BiologicalProcess peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase. RESID:AA0313 go-plus.json http://purl.obolibrary.org/obo/GO_0019927 GO:0019924 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019924 GO:0019925 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019925 GO:0019922 biolink:BiologicalProcess protein-chromophore linkage via peptidyl-cysteine The covalent linking of a chromophore to a protein via peptidyl-cysteines. go-plus.json http://purl.obolibrary.org/obo/GO_0019922 GO:0019923 biolink:BiologicalProcess alpha-1-microglobulin-chromophore linkage The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds. RESID:AA0224 go-plus.json http://purl.obolibrary.org/obo/GO_0019923 GO:0019920 biolink:BiologicalProcess peptidyl-1-thioglycine biosynthetic process, internal The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide. RESID:AA0265 go-plus.json peptidyl-1-thioglycine formation, internal|peptidyl-1-thioglycine anabolism, internal|peptidyl-1-thioglycine synthesis, internal http://purl.obolibrary.org/obo/GO_0019920 UBERON:0018707 biolink:AnatomicalEntity bladder organ A membranous sac in animals that serves as the receptacle of a liquid or contains gas. go-plus.json bladder http://purl.obolibrary.org/obo/UBERON_0018707 GO:0019921 biolink:BiologicalProcess peptidyl-1-thioglycine biosynthetic process, carboxy-terminal The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond. RESID:AA0265 go-plus.json peptidyl-1-thioglycine anabolism, carboxy-terminal|peptidyl-1-thioglycine synthesis, carboxy-terminal|peptidyl-1-thioglycine formation, carboxy-terminal http://purl.obolibrary.org/obo/GO_0019921 CHEBI:57976 biolink:ChemicalSubstance 2-(carboxylatomethyl)-5-oxo-2,5-dihydrofuran-2-ide-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57976 chebi_ph7_3 CHEBI:57977 biolink:ChemicalSubstance bilirubin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57977 chebi_ph7_3 CHEBI:57974 biolink:ChemicalSubstance O-(3-O-D-galactosyl-N-acetyl-beta-D-galactosaminyl)-L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57974 chebi_ph7_3 CHEBI:57975 biolink:ChemicalSubstance 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57975 chebi_ph7_3 CHEBI:57972 biolink:ChemicalSubstance L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57972 chebi_ph7_3 CHEBI:57973 biolink:ChemicalSubstance leukotriene C4(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57973 chebi_ph7_3 CHEBI:57970 biolink:ChemicalSubstance 1-acyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57970 chebi_ph7_3 CHEBI:57971 biolink:ChemicalSubstance hygromycin B(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57971 chebi_ph7_3 GO:0030499 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030499 GO:0030490 biolink:BiologicalProcess maturation of SSU-rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule. go-plus.json SSU-rRNA maturation|processing of 20S pre-rRNA http://purl.obolibrary.org/obo/GO_0030490 GO:0030497 biolink:BiologicalProcess fatty acid elongation The elongation of a fatty acid chain by the sequential addition of two-carbon units. go-plus.json http://purl.obolibrary.org/obo/GO_0030497 GO:0030498 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030498 GO:0030495 biolink:BiologicalProcess bacteriochlorophyll catabolic process The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants. go-plus.json bacteriochlorophyll breakdown|bacteriochlorophyll catabolism|bacteriochlorophyll degradation http://purl.obolibrary.org/obo/GO_0030495 GO:0030496 biolink:CellularComponent midbody A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. Wikipedia:Midbody_(cell_biology) go-plus.json http://purl.obolibrary.org/obo/GO_0030496 goslim_pir GO:0030493 biolink:BiologicalProcess bacteriochlorophyll metabolic process The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants. go-plus.json bacteriochlorophyll metabolism http://purl.obolibrary.org/obo/GO_0030493 GO:0030494 biolink:BiologicalProcess bacteriochlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants. go-plus.json bacteriochlorophyll biosynthesis|bacteriochlorophyll anabolism|bacteriochlorophyll synthesis|bacteriochlorophyll formation http://purl.obolibrary.org/obo/GO_0030494 GO:0030491 biolink:BiologicalProcess heteroduplex formation The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0030491 GO:0030492 biolink:MolecularActivity hemoglobin binding Binding to hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. go-plus.json globin binding|haemoglobin binding http://purl.obolibrary.org/obo/GO_0030492 GO:0030488 biolink:BiologicalProcess tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0030488 GO:0030489 biolink:BiologicalProcess obsolete processing of 27S pre-rRNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json processing of 27S pre-rRNA http://purl.obolibrary.org/obo/GO_0030489 GO:0030486 biolink:CellularComponent smooth muscle dense body Electron-dense region associated with a smooth muscle contractile fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0030486 GO:0030487 biolink:MolecularActivity inositol-4,5-bisphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0030487 GO:0030484 biolink:CellularComponent obsolete muscle fiber OBSOLETE. The contractile fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. go-plus.json muscle fibre|muscle fiber http://purl.obolibrary.org/obo/GO_0030484 GO:0030485 biolink:CellularComponent smooth muscle contractile fiber The contractile fiber of smooth muscle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0030485 GO:0030482 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030482 GO:0030483 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030483 GO:0030480 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030480 GO:0030481 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030481 GO:0030479 biolink:CellularComponent actin cortical patch An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae. go-plus.json actin patch http://purl.obolibrary.org/obo/GO_0030479 GO:0030477 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030477 GO:0030478 biolink:CellularComponent actin cap Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0030478 OBO:GOCHE_71300 biolink:OntologyClass substance with EC 2.* (transferase) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_71300 3_STAR GO:0030475 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030475 GO:0030476 biolink:BiologicalProcess ascospore wall assembly The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae. go-plus.json spore wall assembly http://purl.obolibrary.org/obo/GO_0030476 GO:0030473 biolink:BiologicalProcess nuclear migration along microtubule The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. go-plus.json transport of nucleus, microtubule-mediated|microtubule-mediated nuclear migration|microtubule cytoskeleton-dependent nuclear positioning|nuclear movement, microtubule-mediated|nucleus migration|nuclear migration, microtubule-mediated|microtubule-dependent nucleus positioning|transport of nucleus by microtubules|microtubule cytoskeleton-dependent nucleus positioning|microtubule-dependent nuclear positioning http://purl.obolibrary.org/obo/GO_0030473 GO:0030474 biolink:BiologicalProcess spindle pole body duplication Construction of a new spindle pole body. go-plus.json spindle pole body assembly|spindle pole body duplication in cytoplasm|spindle pole body biogenesis|spindle pole body duplication associated with nuclear envelope|spindle pole body formation|spindle pole body replication|spindle pole body biosynthesis http://purl.obolibrary.org/obo/GO_0030474 GO:0030471 biolink:BiologicalProcess obsolete spindle pole body and microtubule cycle (sensu Fungi) OBSOLETE. The dynamics of the spindle pole body and microtubule cytoskeleton during the cell cycle. Includes spindle pole body duplication and separation and formation and elongation of the mitotic spindle. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751). go-plus.json spindle pole body and microtubule cycle (sensu Saccharomyces)|spindle pole body and microtubule cycle (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030471 GO:0030472 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030472 GO:0030470 biolink:BiologicalProcess obsolete spore germination (sensu Fungi) OBSOLETE. Process of breakdown or opening of the spore-containing structure, modification of the spore wall, and resumption of growth of the spore. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751). go-plus.json spore germination (sensu Fungi)|germination (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0030470 GO:0030468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030468 GO:0030469 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030469 GO:0030466 biolink:BiologicalProcess silent mating-type cassette heterochromatin assembly Repression of transcription at silent mating-type loci by alteration of the structure of chromatin. go-plus.json establishment of chromatin silencing at silent mating-type cassette|aging-dependent sterility|heterochromatic silencing at silent mating-type cassette|chromatin silencing at HML and HMR|silent mating-type cassette chromatin silencing|chromatin silencing at silent mating-type cassette http://purl.obolibrary.org/obo/GO_0030466 GO:0030467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030467 GO:0030464 biolink:BiologicalProcess obsolete aging dependent sterility (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json aging dependent sterility (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030464 GO:0030465 biolink:BiologicalProcess obsolete autophagic death (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json autophagic death (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030465 GO:0030462 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030462 GO:0030463 biolink:BiologicalProcess obsolete cell aging (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json cell aging (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030463 GO:0030460 biolink:BiologicalProcess obsolete nuclear translocation of MAPK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json nuclear translocation of MAPK (mating sensu Fungi) http://purl.obolibrary.org/obo/GO_0030460 GO:0030461 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030461 GO:0030459 biolink:BiologicalProcess obsolete inactivation of MAPK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json inactivation of MAPK (mating sensu Fungi) http://purl.obolibrary.org/obo/GO_0030459 GO:0030457 biolink:BiologicalProcess obsolete activation of MAPKK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of MAPKK (mating sensu Fungi) http://purl.obolibrary.org/obo/GO_0030457 GO:0030458 biolink:BiologicalProcess obsolete activation of MAPKKK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of MAPKKK (mating sensu Fungi) http://purl.obolibrary.org/obo/GO_0030458 GO:0005499 biolink:MolecularActivity vitamin D binding Binding to vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json ergocalciferol binding|cholecalciferol binding|calciferol binding http://purl.obolibrary.org/obo/GO_0005499 GO:0030455 biolink:BiologicalProcess obsolete MAPKKK cascade (mating sensu Fungi) OBSOLETE. MAPKKK cascade involved in transducing mating pheromone signal in a fungus. go-plus.json MAPKKK cascade (mating sensu Fungi) http://purl.obolibrary.org/obo/GO_0030455 GO:0030456 biolink:BiologicalProcess obsolete activation of MAPK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of MAPK (mating sensu Fungi) http://purl.obolibrary.org/obo/GO_0030456 GO:0005497 biolink:MolecularActivity androgen binding Binding to an androgen, a male sex hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0005497 RO:0002495 biolink:OntologyClass RO:0002495 go-plus.json immediately transforms from|direct_transformation_of http://purl.obolibrary.org/obo/RO_0002495 GO:0005498 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005498 RO:0002496 biolink:OntologyClass RO:0002496 go-plus.json http://purl.obolibrary.org/obo/RO_0002496 CHEBI:140991 biolink:ChemicalSubstance omega-methyl-long-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140991 chebi_ph7_3 RO:0002497 biolink:OntologyClass RO:0002497 go-plus.json http://purl.obolibrary.org/obo/RO_0002497 CHEBI:140992 biolink:ChemicalSubstance omega-hydroxy-long-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140992 chebi_ph7_3 GO:0005496 biolink:MolecularActivity steroid binding Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. go-plus.json http://purl.obolibrary.org/obo/GO_0005496 goslim_pir RO:0002491 biolink:OntologyClass RO:0002491 go-plus.json http://purl.obolibrary.org/obo/RO_0002491 RO:0002492 biolink:OntologyClass Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. RO:0002492 go-plus.json ceases_to_exist_during http://purl.obolibrary.org/obo/RO_0002492 RO:0002493 biolink:OntologyClass Relation between continuant and occurrent, such that c ceases to exist at the end of p. RO:0002493 go-plus.json http://purl.obolibrary.org/obo/RO_0002493 RO:0002494 biolink:OntologyClass transformation of x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships RO:0002494 go-plus.json transforms from http://purl.obolibrary.org/obo/RO_0002494 RO:0002488 biolink:OntologyClass Relation between continuant c and occurrent s, such that every instance of c comes into existing during some s. RO:0002488 go-plus.json begins_to_exist_during http://purl.obolibrary.org/obo/RO_0002488 CHEBI:140997 biolink:ChemicalSubstance omega-hydroxy-long-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140997 RO:0002489 biolink:OntologyClass Relation between continuant and occurrent, such that c comes into existence at the start of p. RO:0002489 go-plus.json http://purl.obolibrary.org/obo/RO_0002489 GO:0030453 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030453 GO:0030454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030454 GO:0030451 biolink:BiologicalProcess regulation of complement activation, alternative pathway Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation. go-plus.json regulation of complement cascade, alternative pathway http://purl.obolibrary.org/obo/GO_0030451 GO:0030452 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030452 GO:0030450 biolink:BiologicalProcess regulation of complement activation, classical pathway Any process that modulates the frequency, rate or extent of the classical pathway of complement activation. go-plus.json regulation of complement cascade, classical pathway http://purl.obolibrary.org/obo/GO_0030450 GO:0030448 biolink:BiologicalProcess hyphal growth Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls. go-plus.json formation of symbiont invasive hypha within host during symbiotic interaction|symbiont invasive hypha formation within host|formation of symbiont invasive hypha in host|formation of symbiont invasive hypha within host|invasive hyphal growth http://purl.obolibrary.org/obo/GO_0030448 goslim_candida GO:0030449 biolink:BiologicalProcess regulation of complement activation Any process that modulates the frequency, rate or extent of complement activation. go-plus.json regulation of complement cascade http://purl.obolibrary.org/obo/GO_0030449 GO:0030446 biolink:CellularComponent hyphal cell wall The cell wall surrounding a fungal hypha. go-plus.json http://purl.obolibrary.org/obo/GO_0030446 GO:0030447 biolink:BiologicalProcess filamentous growth The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0030447 goslim_candida|goslim_aspergillus GO:0030444 biolink:BiologicalProcess obsolete microtubule depolymerization during nuclear congression OBSOLETE. (Was not defined before being made obsolete). go-plus.json microtubule depolymerization during nuclear congression http://purl.obolibrary.org/obo/GO_0030444 GO:0030445 biolink:CellularComponent yeast-form cell wall The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form. go-plus.json http://purl.obolibrary.org/obo/GO_0030445 RO:0002479 biolink:OntologyClass has part that occurs in p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. RO:0002479 go-plus.json http://purl.obolibrary.org/obo/RO_0002479 GO:0030442 biolink:BiologicalProcess obsolete inactivation of MAPK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json inactivation of MAPK during sporulation (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030442 GO:0030443 biolink:BiologicalProcess obsolete nuclear translocation of MAPK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json nuclear translocation of MAPK during sporulation (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030443 GO:0030440 biolink:BiologicalProcess obsolete activation of MAPKK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of MAPKK during sporulation (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030440 GO:0030441 biolink:BiologicalProcess obsolete activation of MAPKKK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of MAPKKK during sporulation (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030441 GO:0030439 biolink:BiologicalProcess obsolete activation of MAPK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of MAPK during sporulation (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030439 GO:0030437 biolink:BiologicalProcess ascospore formation The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota). go-plus.json ascospore biosynthesis|sporulation|spore formation http://purl.obolibrary.org/obo/GO_0030437 goslim_pombe GO:0030438 biolink:BiologicalProcess obsolete MAPKKK cascade during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). go-plus.json MAPKKK cascade during sporulation (sensu Fungi) http://purl.obolibrary.org/obo/GO_0030438 CHEBI:149304 biolink:ChemicalSubstance L-galactofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_149304 chebi_ph7_3 GO:0030435 biolink:BiologicalProcess sporulation resulting in formation of a cellular spore The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. Wikipedia:Sporogenesis go-plus.json spore biosynthesis|cellular spore formation by sporulation|spore formation|spore differentiation http://purl.obolibrary.org/obo/GO_0030435 GO:0005479 biolink:MolecularActivity obsolete vacuolar assembly OBSOLETE. (Was not defined before being made obsolete). go-plus.json vacuolar assembly http://purl.obolibrary.org/obo/GO_0005479 GO:0030436 biolink:BiologicalProcess asexual sporulation The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi. go-plus.json asexual reproductive sporulation|mitotic sporulation|asexual spore formation|mitotic spore formation http://purl.obolibrary.org/obo/GO_0030436 goslim_aspergillus GO:0030433 biolink:BiologicalProcess ubiquitin-dependent ERAD pathway The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. go-plus.json endoplasmic reticulum-associated ubiquitin-dependent protein catabolic process|ERAD|endoplasmic reticulum-associated ubiqutin-dependent protein catabolism|ER-associated ubiquitin-dependent protein catabolism|ER-associated ubiquitin-dependent protein catabolic process|ubiquitin-dependent proteasomal protein catabolism of ER proteins|ER-associated ubiquitin-dependent protein degradation|ER-associated ubiquitin-dependent protein breakdown http://purl.obolibrary.org/obo/GO_0030433 GO:0005477 biolink:MolecularActivity pyruvate secondary active transmembrane transporter activity Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json pyruvate carrier activity http://purl.obolibrary.org/obo/GO_0005477 GO:0030434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030434 GO:0005478 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005478 RO:0002473 biolink:OntologyClass x composed_primarily_of y iff: more than half of the mass of x is made from parts of y RO:0002473 go-plus.json http://purl.obolibrary.org/obo/RO_0002473 GO:0005476 biolink:MolecularActivity carnitine:acyl carnitine antiporter activity Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial). go-plus.json carnitine/acyl carnitine carrier activity|fatty acyl carnitine carrier|carnitine:acyl carnitine carrier activity http://purl.obolibrary.org/obo/GO_0005476 GO:0005471 biolink:MolecularActivity ATP:ADP antiporter activity Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out). go-plus.json adenine nucleotide translocase|ADP/ATP carrier protein|ADP/ATP translocase|ATP/ADP exchanger|ATP/ADP exchange http://purl.obolibrary.org/obo/GO_0005471 GO:0005472 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005472 GO:0030431 biolink:BiologicalProcess sleep Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. Wikipedia:Sleep go-plus.json dormancy|lethargus|diapause http://purl.obolibrary.org/obo/GO_0030431 goslim_pir GO:0030432 biolink:BiologicalProcess peristalsis A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. Wikipedia:Peristalsis go-plus.json http://purl.obolibrary.org/obo/GO_0030432 CHEBI:5580 biolink:ChemicalSubstance gypsogenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_5580 GO:0030430 biolink:CellularComponent host cell cytoplasm The cytoplasm of a host cell. go-plus.json other organism cytoplasm http://purl.obolibrary.org/obo/GO_0030430 CHEBI:5587 biolink:ChemicalSubstance sulfurothioic S-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_5587 GO:0030428 biolink:CellularComponent cell septum A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. go-plus.json cross wall|septum http://purl.obolibrary.org/obo/GO_0030428 goslim_pir GO:0030429 biolink:MolecularActivity kynureninase activity Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine. MetaCyc:KYNURENINASE-RXN|RHEA:16813|Reactome:R-HSA-71217|EC:3.7.1.3 go-plus.json kynurenine hydrolase activity|L-kynurenine hydrolase activity http://purl.obolibrary.org/obo/GO_0030429 GO:0030426 biolink:CellularComponent growth cone The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic. Wikipedia:Growth_cone go-plus.json http://purl.obolibrary.org/obo/GO_0030426 GO:0030427 biolink:CellularComponent site of polarized growth Any part of a cell where non-isotropic growth takes place. go-plus.json http://purl.obolibrary.org/obo/GO_0030427 goslim_candida|goslim_yeast|goslim_pir|goslim_aspergillus GO:0030424 biolink:CellularComponent axon The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. Wikipedia:Axon|NIF_Subcellular:sao1770195789 go-plus.json http://purl.obolibrary.org/obo/GO_0030424 CHEBI:43291 biolink:ChemicalSubstance L-erythro-isocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43291 GO:0030425 biolink:CellularComponent dendrite A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. NIF_Subcellular:sao1211023249|Wikipedia:Dendrite go-plus.json http://purl.obolibrary.org/obo/GO_0030425 GO:0030422 biolink:BiologicalProcess production of siRNA involved in RNA interference Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference. go-plus.json RNA interference, production of siRNA|production of guide RNAs involved in RNA interference|RNA interference, production of guide RNAs http://purl.obolibrary.org/obo/GO_0030422 GO:0005488 biolink:MolecularActivity binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. Wikipedia:Binding_(molecular) go-plus.json ligand http://purl.obolibrary.org/obo/GO_0005488 gocheck_do_not_annotate|goslim_pir|goslim_plant GO:0030423 biolink:BiologicalProcess targeting of mRNA for destruction involved in RNA interference The process in which small interfering RNAs target cognate mRNA molecules for degradation. go-plus.json RNA interference, targeting of mRNA for destruction http://purl.obolibrary.org/obo/GO_0030423 GO:0005489 biolink:MolecularActivity obsolete electron transporter activity OBSOLETE. Enables the directed movement of electrons into, out of, within or between cells. go-plus.json cytochrome c3 (tetraheme)|cytochrome d|class I cytochrome c|class III cytochrome c|cytochrome b|cytochrome b5|cytochrome c554|class II cytochrome c|nonaheme cytochrome c|electron transfer carrier|Rieske iron-sulfur protein|flavodoxin|flavin-containing electron transporter|electron transporter activity|cytochrome c7 (triheme)|class IV cytochrome c|high-molecular-weight cytochrome c (hexadecaheme)|class IIa cytochrome c|monoheme class I cytochrome c|class IIb cytochrome c|respiratory chain cytochrome b6|diheme class I cytochrome c http://purl.obolibrary.org/obo/GO_0005489 GO:0005486 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005486 GO:0005487 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005487 GO:0005484 biolink:MolecularActivity SNAP receptor activity Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion. go-plus.json SNARE|Q-SNARE activity|R-SNARE activity|t-SNARE activity|v-SNARE activity|SNAP-25 http://purl.obolibrary.org/obo/GO_0005484 goslim_chembl GO:0005485 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005485 GO:0005482 biolink:MolecularActivity obsolete vesicle targeting OBSOLETE. (Was not defined before being made obsolete). go-plus.json vesicle targeting http://purl.obolibrary.org/obo/GO_0005482 GO:0005483 biolink:MolecularActivity soluble NSF attachment protein activity Binding to both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex. go-plus.json SNAP http://purl.obolibrary.org/obo/GO_0005483 GO:0005480 biolink:MolecularActivity obsolete vesicle transport OBSOLETE. (Was not defined before being made obsolete). go-plus.json vesicle transport http://purl.obolibrary.org/obo/GO_0005480 GO:0005481 biolink:MolecularActivity obsolete vesicle fusion OBSOLETE. (Was not defined before being made obsolete). go-plus.json vesicle fusion http://purl.obolibrary.org/obo/GO_0005481 GO:0005490 biolink:MolecularActivity obsolete cytochrome P450 OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates. go-plus.json cytochrome P450 http://purl.obolibrary.org/obo/GO_0005490 GO:0030420 biolink:BiologicalProcess establishment of competence for transformation The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation. go-plus.json http://purl.obolibrary.org/obo/GO_0030420 GO:0030421 biolink:BiologicalProcess defecation The expulsion of feces from the rectum. Wikipedia:Defecation go-plus.json http://purl.obolibrary.org/obo/GO_0030421 CHEBI:67250 biolink:ChemicalSubstance secoisolariciresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67250 UBERON:0018389 biolink:AnatomicalEntity interoceptor A sensory receptor that detects stimulus within the body. Examples of stimuli that would be detected by interoceptors include blood pressure and blood oxygen level. go-plus.json enteroceptor|visceroceptor http://purl.obolibrary.org/obo/UBERON_0018389 CHEBI:67253 biolink:ChemicalSubstance alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67253 CHEBI:33913 biolink:ChemicalSubstance corrinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33913 chebi_ph7_3 CHEBI:33914 biolink:ChemicalSubstance aldotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33914 CHEBI:33915 biolink:ChemicalSubstance aldotetrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33915 PR:000004140 biolink:Protein apolipoprotein A-I A protein that is a translation product of the human APOA1 gene or a 1:1 ortholog thereof. go-plus.json APOA1|apolipoprotein A1|ApoA-I|apo-AI http://purl.obolibrary.org/obo/PR_000004140 CHEBI:33916 biolink:ChemicalSubstance aldopentose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33916 CHEBI:67256 biolink:ChemicalSubstance beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67256 CHEBI:33917 biolink:ChemicalSubstance aldohexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33917 RO:0002450 biolink:OntologyClass directly positively regulates activity of The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. RO:0002450 go-plus.json molecularly increases activity of http://purl.obolibrary.org/obo/RO_0002450 CHEBI:82883 biolink:ChemicalSubstance nucleotide 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82883 chebi_ph7_3 RO:0002448 biolink:OntologyClass directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. RO:0002448 go-plus.json molecularly controls http://purl.obolibrary.org/obo/RO_0002448 PR:000004135 biolink:Protein apelin A protein that is a translation product of the human APLN gene or a 1:1 ortholog thereof. go-plus.json APJ endogenous ligand|APEL|APLN http://purl.obolibrary.org/obo/PR_000004135 RO:0002449 biolink:OntologyClass directly negatively regulates activity of The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. RO:0002449 go-plus.json molecularly decreases activity of http://purl.obolibrary.org/obo/RO_0002449 CHEBI:82881 biolink:ChemicalSubstance N-acylhexadecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82881 chebi_ph7_3 RO:0002447 biolink:OntologyClass phosphorylates RO:0002447 go-plus.json http://purl.obolibrary.org/obo/RO_0002447 CHEBI:67261 biolink:ChemicalSubstance (Z)-2,3-dehydroadipyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67261 chebi_ph7_3 CHEBI:67262 biolink:ChemicalSubstance dihydrocurcumin go-plus.json http://purl.obolibrary.org/obo/CHEBI_67262 chebi_ph7_3 CHEBI:67263 biolink:ChemicalSubstance tetrahydrocurcumin go-plus.json http://purl.obolibrary.org/obo/CHEBI_67263 chebi_ph7_3 CHEBI:67264 biolink:ChemicalSubstance geranic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67264 CHEBI:67260 biolink:ChemicalSubstance geranate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67260 chebi_ph7_3 CHEBI:67269 biolink:ChemicalSubstance cyclo(L-leucyl-L-leucyl) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67269 chebi_ph7_3 CHEBI:33921 biolink:ChemicalSubstance ketoaldohexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33921 CHEBI:33922 biolink:ChemicalSubstance sugar dianhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_33922 CHEBI:82897 biolink:ChemicalSubstance (S)-miconazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_82897 chebi_ph7_3 CHEBI:67265 biolink:ChemicalSubstance beta-diketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_67265 CHEBI:33926 biolink:ChemicalSubstance dialdose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33926 CHEBI:82894 biolink:ChemicalSubstance (R)-miconazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_82894 chebi_ph7_3 CHEBI:82891 biolink:ChemicalSubstance glucocorticoid receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_82891 CHEBI:82892 biolink:ChemicalSubstance 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_82892 chebi_ph7_3 RO:0002433 biolink:OntologyClass RO:0002433 go-plus.json http://purl.obolibrary.org/obo/RO_0002433 RO:0002434 biolink:OntologyClass interacts with A relationship that holds between two entities in which the processes executed by the two entities are causally connected. RO:0002434 go-plus.json in pairwise interaction with http://purl.obolibrary.org/obo/RO_0002434 RO:0002436 biolink:OntologyClass molecularly interacts with An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. RO:0002436 go-plus.json http://purl.obolibrary.org/obo/RO_0002436 CHEBI:33920 biolink:ChemicalSubstance ketoaldose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33920 CHEBI:67273 biolink:ChemicalSubstance monohydroxy-1,4-benzoquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_67273 chebi_ph7_3 CHEBI:67274 biolink:ChemicalSubstance lysophosphatidylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_67274 chebi_ph7_3 RO:0002430 biolink:OntologyClass involved in negative regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p RO:0002430 go-plus.json http://purl.obolibrary.org/obo/RO_0002430 RO:0002431 biolink:OntologyClass involved in or involved in regulation of c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p RO:0002431 go-plus.json http://purl.obolibrary.org/obo/RO_0002431 RO:0002432 biolink:OntologyClass is active in c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. RO:0002432 go-plus.json enables activity in http://purl.obolibrary.org/obo/RO_0002432 NCBITaxon:29655 biolink:OrganismalEntity Zostera marina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_29655 RO:0002427 biolink:OntologyClass causally downstream of or within inverse of causally upstream of or within RO:0002427 go-plus.json http://purl.obolibrary.org/obo/RO_0002427 RO:0002428 biolink:OntologyClass involved in regulation of c involved in regulation of p if c is involved in some p' and p' regulates some p RO:0002428 go-plus.json http://purl.obolibrary.org/obo/RO_0002428 RO:0002429 biolink:OntologyClass involved in positive regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p RO:0002429 go-plus.json http://purl.obolibrary.org/obo/RO_0002429 CHEBI:33907 biolink:ChemicalSubstance cob(III)yrinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33907 CHEBI:33909 biolink:ChemicalSubstance metallotetrapyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_33909 CHEBI:33900 biolink:ChemicalSubstance tagaturonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33900 CHEBI:33901 biolink:ChemicalSubstance fructuronates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33901 CHEBI:33903 biolink:ChemicalSubstance glucuronates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33903 CHEBI:33905 biolink:ChemicalSubstance heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33905 CHEBI:33906 biolink:ChemicalSubstance cobalt corrinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33906 RO:0002418 biolink:OntologyClass causally upstream of or within p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q. RO:0002418 go-plus.json affects http://purl.obolibrary.org/obo/RO_0002418 RO:0002411 biolink:OntologyClass causally upstream of p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain RO:0002411 go-plus.json http://purl.obolibrary.org/obo/RO_0002411 RO:0002412 biolink:OntologyClass immediately causally upstream of p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q. RO:0002412 go-plus.json http://purl.obolibrary.org/obo/RO_0002412 PR:000004126 biolink:Protein serum amyloid P-component A protein that is a translation product of the human APCS gene or a 1:1 ortholog thereof. go-plus.json SAP|APCS|9.5S alpha-1-glycoprotein|PTX2 http://purl.obolibrary.org/obo/PR_000004126 RO:0002410 biolink:OntologyClass causally related to This relation groups causal relations between material entities and causal relations between processes RO:0002410 go-plus.json http://purl.obolibrary.org/obo/RO_0002410 RO:0002404 biolink:OntologyClass causally downstream of inverse of upstream of RO:0002404 go-plus.json http://purl.obolibrary.org/obo/RO_0002404 RO:0002405 biolink:OntologyClass immediately causally downstream of RO:0002405 go-plus.json http://purl.obolibrary.org/obo/RO_0002405 NCBITaxon:6407 biolink:OrganismalEntity Glossiphoniidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6407 NCBITaxon:6406 biolink:OrganismalEntity Rhynchobdellida go-plus.json Rhynchobdelliformes http://purl.obolibrary.org/obo/NCBITaxon_6406 PR:000004191 biolink:Protein androgen receptor A protein that is a translation product of the human AR gene or a 1:1 ortholog thereof. go-plus.json dihydrotestosterone receptor|AR|nuclear receptor subfamily 3 group C member 4|DHTR|NR3C4 http://purl.obolibrary.org/obo/PR_000004191 NCBITaxon:6411 biolink:OrganismalEntity Helobdella go-plus.json Desmobdella http://purl.obolibrary.org/obo/NCBITaxon_6411 PR:000004168 biolink:Protein amyloid-beta precursor protein A protein that is a translation product of the human APP gene or a 1:1 ortholog thereof. go-plus.json PN-II|cerebral vascular amyloid peptide|A4|alzheimer disease amyloid A4 protein homolog|AD1|APPI|alzheimer disease amyloid protein|AG|amyloid-beta A4 protein|CVAP|ABPP|APP|amyloidogenic glycoprotein|PreA4|protease nexin-II|amyloid beta A4 protein http://purl.obolibrary.org/obo/PR_000004168 UBERON:0018391 biolink:AnatomicalEntity chemoreceptor A sensory receptor that detects chemical stimulus within the body. go-plus.json http://purl.obolibrary.org/obo/UBERON_0018391 CHEBI:18240 biolink:ChemicalSubstance 4-hydroxy-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_18240 CHEBI:57848 biolink:ChemicalSubstance 1,4-diguanidiniumylbutane go-plus.json http://purl.obolibrary.org/obo/CHEBI_57848 chebi_ph7_3 CHEBI:57849 biolink:ChemicalSubstance (R)-4-dehydropantoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57849 chebi_ph7_3 CHEBI:57846 biolink:ChemicalSubstance L-fuculose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57846 chebi_ph7_3 CHEBI:57847 biolink:ChemicalSubstance UDP-N-acetyl-D-galactosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57847 chebi_ph7_3 CHEBI:82803 biolink:ChemicalSubstance opine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82803 CHEBI:82800 biolink:ChemicalSubstance (R)-cembrene A go-plus.json http://purl.obolibrary.org/obo/CHEBI_82800 chebi_ph7_3 CHEBI:82801 biolink:ChemicalSubstance (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82801 chebi_ph7_3 CHEBI:33871 biolink:ChemicalSubstance glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33871 chebi_ph7_3 CHEBI:18239 biolink:ChemicalSubstance ditrans,polycis-decaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18239 CHEBI:57844 biolink:ChemicalSubstance L-methionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57844 chebi_ph7_3 CHEBI:18236 biolink:ChemicalSubstance 6-demethylsterigmatocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18236 chebi_ph7_3 CHEBI:57845 biolink:ChemicalSubstance preuroporphyrinogen(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57845 chebi_ph7_3 CHEBI:18237 biolink:ChemicalSubstance glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18237 CHEBI:18234 biolink:ChemicalSubstance alpha,alpha'-trehalose 6-mycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18234 chebi_ph7_3 CHEBI:57842 biolink:ChemicalSubstance vitexin 2''-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57842 chebi_ph7_3 CHEBI:57843 biolink:ChemicalSubstance L-selenocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57843 chebi_ph7_3 CHEBI:57840 biolink:ChemicalSubstance methylguanidinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57840 chebi_ph7_3 CHEBI:18232 biolink:ChemicalSubstance D-galactosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18232 CHEBI:57841 biolink:ChemicalSubstance 4-amino-2-methyl-5-diphosphonatooxymethylpyrimidine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57841 chebi_ph7_3 CHEBI:18233 biolink:ChemicalSubstance xyloglucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_18233 CHEBI:18230 biolink:ChemicalSubstance chlorophyll a go-plus.json http://purl.obolibrary.org/obo/CHEBI_18230 CHEBI:18231 biolink:ChemicalSubstance arsenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18231 CHEBI:57839 biolink:ChemicalSubstance 3-dehydro-2-deoxy-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57839 chebi_ph7_3 CHEBI:57837 biolink:ChemicalSubstance dTDP-4-dehydro-6-deoxy-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57837 chebi_ph7_3 CHEBI:82815 biolink:ChemicalSubstance 3-(methylthio)propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82815 chebi_ph7_3 CHEBI:57838 biolink:ChemicalSubstance N-phosphonatotaurocyamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57838 chebi_ph7_3 CHEBI:57835 biolink:ChemicalSubstance glutathionylspermidinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57835 chebi_ph7_3 CHEBI:57836 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57836 chebi_ph7_3 CHEBI:33888 biolink:ChemicalSubstance cobalt molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33888 CHEBI:82811 biolink:ChemicalSubstance N-stearoylhexadecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82811 chebi_ph7_3 CHEBI:82810 biolink:ChemicalSubstance N-palmitoylhexadecasphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82810 chebi_ph7_3 UBERON:0018415 biolink:AnatomicalEntity ethmoid foramen An bone foramen in the ethmoid bone. go-plus.json ethmoid foramina|ethmoidal foramina|foramina ethmoidalia|ethmoidal foramen http://purl.obolibrary.org/obo/UBERON_0018415 UBERON:0018413 biolink:AnatomicalEntity facial nerve canal A Z-shaped canal running through the temporal bone from the internal acoustic meatus to the stylomastoid foramen. It is located within the middle ear region, according to its shape it is divided into three main segments: the labyrinthine, the tympanic, and the mastoidal segment . go-plus.json fallopian canal|facial canal|canalis nervi facialis http://purl.obolibrary.org/obo/UBERON_0018413 CHEBI:33883 biolink:ChemicalSubstance fructuronic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_33883 CHEBI:18229 biolink:ChemicalSubstance deacetoxycephalosporin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_18229 CHEBI:33885 biolink:ChemicalSubstance alpha-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33885 CHEBI:18227 biolink:ChemicalSubstance sterigmatocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18227 chebi_ph7_3 CHEBI:33886 biolink:ChemicalSubstance glucuronic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_33886 CHEBI:18228 biolink:ChemicalSubstance 1D-myo-inositol 1,3,4-trisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18228 CHEBI:57833 biolink:ChemicalSubstance N-benzoyl-4-hydroxyanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57833 chebi_ph7_3 CHEBI:18225 biolink:ChemicalSubstance myo-inositol 1,3-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18225 CHEBI:57834 biolink:ChemicalSubstance spermidine(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57834 chebi_ph7_3 CHEBI:18226 biolink:ChemicalSubstance (R)-6-hydroxynicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18226 CHEBI:57831 biolink:ChemicalSubstance glycerol 1,2-cyclic phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57831 chebi_ph7_3 CHEBI:57832 biolink:ChemicalSubstance 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57832 chebi_ph7_3 CHEBI:18224 biolink:ChemicalSubstance isoeugenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18224 chebi_ph7_3 CHEBI:57830 biolink:ChemicalSubstance cyanidin 3-O-rutinoside 5-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57830 chebi_ph7_3 CHEBI:18222 biolink:ChemicalSubstance xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18222 CHEBI:18220 biolink:ChemicalSubstance isoflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18220 chebi_ph7_3 CHEBI:18261 biolink:ChemicalSubstance N-carbamoyl-beta-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18261 CHEBI:18262 biolink:ChemicalSubstance dodecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18262 chebi_ph7_3 CHEBI:57828 biolink:ChemicalSubstance D-hamamelose 2(1)-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57828 chebi_ph7_3 CHEBI:82828 biolink:ChemicalSubstance oleanolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82828 chebi_ph7_3 CHEBI:82829 biolink:ChemicalSubstance sphinganine-based sphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82829 chebi_ph7_3 CHEBI:57829 biolink:ChemicalSubstance L-xylulose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57829 chebi_ph7_3 CHEBI:57826 biolink:ChemicalSubstance 6-aminohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57826 chebi_ph7_3 CHEBI:82827 biolink:ChemicalSubstance oleanolic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_82827 chebi_ph7_3 CHEBI:57824 biolink:ChemicalSubstance oxalurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57824 chebi_ph7_3 NCBITaxon:6412 biolink:OrganismalEntity Helobdella robusta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6412 CHEBI:57825 biolink:ChemicalSubstance L-lombricine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57825 chebi_ph7_3 CHEBI:33855 biolink:ChemicalSubstance arenecarbaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_33855 chebi_ph7_3 CHEBI:33856 biolink:ChemicalSubstance aromatic amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33856 CHEBI:33857 biolink:ChemicalSubstance aromatic primary alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33857 chebi_ph7_3 CHEBI:33859 biolink:ChemicalSubstance aromatic carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33859 CHEBI:33853 biolink:ChemicalSubstance phenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_33853 chebi_ph7_3 CHEBI:33854 biolink:ChemicalSubstance aromatic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33854 chebi_ph7_3 CHEBI:57822 biolink:ChemicalSubstance D-alanyl-D-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57822 chebi_ph7_3 CHEBI:18258 biolink:ChemicalSubstance 3,3',5-triiodo-L-thyronine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18258 CHEBI:18259 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18259 chebi_ph7_3 CHEBI:57823 biolink:ChemicalSubstance 4-CDP-2-C-methyl-D-erythritol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57823 chebi_ph7_3 CHEBI:57820 biolink:ChemicalSubstance N(6)-hydroxy-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57820 chebi_ph7_3 CHEBI:18256 biolink:ChemicalSubstance 4-formylbenzenesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18256 CHEBI:18257 biolink:ChemicalSubstance ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18257 CHEBI:18254 biolink:ChemicalSubstance ribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_18254 chebi_ph7_3 CHEBI:18255 biolink:ChemicalSubstance nebularine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18255 chebi_ph7_3 CHEBI:18252 biolink:ChemicalSubstance zymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18252 chebi_ph7_3 CHEBI:18253 biolink:ChemicalSubstance 5-guanidino-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18253 CHEBI:57819 biolink:ChemicalSubstance quinolin-4(1H)-one-3-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57819 CHEBI:18250 biolink:ChemicalSubstance chondroitin 4'-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18250 CHEBI:18251 biolink:ChemicalSubstance UDP-D-galactofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18251 CHEBI:57817 biolink:ChemicalSubstance sphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57817 chebi_ph7_3 CHEBI:82839 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82839 CHEBI:57818 biolink:ChemicalSubstance 5,10-methylenetetrahydromethanopterin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57818 chebi_ph7_3 NCBITaxon:1903411 biolink:OrganismalEntity Yersiniaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1903411 CHEBI:82837 biolink:ChemicalSubstance 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82837 CHEBI:57815 biolink:ChemicalSubstance luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] go-plus.json http://purl.obolibrary.org/obo/CHEBI_57815 CHEBI:57813 biolink:ChemicalSubstance quercetin 3,3',7-trissulfate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57813 CHEBI:57814 biolink:ChemicalSubstance triacetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57814 chebi_ph7_3 CHEBI:82836 biolink:ChemicalSubstance (9Z)-hexacosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82836 CHEBI:82833 biolink:ChemicalSubstance 7-aminomethyl-7-carbaguanine 5'-phosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82833 chebi_ph7_3 CHEBI:33866 biolink:ChemicalSubstance mannonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33866 CHEBI:67204 biolink:ChemicalSubstance carboxynorspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67204 CHEBI:82834 biolink:ChemicalSubstance epoxyqueuosine 5'-phosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82834 chebi_ph7_3 CHEBI:33867 biolink:ChemicalSubstance idonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33867 CHEBI:67205 biolink:ChemicalSubstance (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67205 CHEBI:82831 biolink:ChemicalSubstance queuosine 5'-phosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82831 chebi_ph7_3 CHEBI:33868 biolink:ChemicalSubstance altronates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33868 CHEBI:33869 biolink:ChemicalSubstance ribonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33869 CHEBI:82830 biolink:ChemicalSubstance sphingosine-based sphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_82830 chebi_ph7_3 CHEBI:67200 biolink:ChemicalSubstance provitamin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_67200 CHEBI:67201 biolink:ChemicalSubstance synthetic cannabinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67201 CHEBI:33860 biolink:ChemicalSubstance aromatic amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_33860 CHEBI:33861 biolink:ChemicalSubstance transition element coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33861 CHEBI:33862 biolink:ChemicalSubstance platinum coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33862 CHEBI:67208 biolink:ChemicalSubstance double-stranded RNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_67208 CHEBI:67209 biolink:ChemicalSubstance alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67209 chebi_ph7_3 CHEBI:18249 biolink:ChemicalSubstance ergosta-5,7,22,24(28)-tetraen-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18249 chebi_ph7_3 CHEBI:33864 biolink:ChemicalSubstance gulonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33864 CHEBI:33865 biolink:ChemicalSubstance rhamnonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33865 CHEBI:57811 biolink:ChemicalSubstance sym-homospermidinium(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57811 chebi_ph7_3 CHEBI:18247 biolink:ChemicalSubstance 5-amino-6-(5-phospho-D-ribitylamino)uracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_18247 CHEBI:57812 biolink:ChemicalSubstance CMP-N-acetyl-beta-neuraminate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57812 chebi_ph7_3 CHEBI:18248 biolink:ChemicalSubstance iron atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_18248 chebi_ph7_3 CHEBI:57810 biolink:ChemicalSubstance UDP-4-dehydro-6-deoxy-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57810 chebi_ph7_3 CHEBI:18246 biolink:ChemicalSubstance (1->4)-beta-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_18246 chebi_ph7_3 CHEBI:18243 biolink:ChemicalSubstance dopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18243 CHEBI:18244 biolink:ChemicalSubstance 1-alkyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18244 CHEBI:18241 biolink:ChemicalSubstance 2'-deoxyribonucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18241 CHEBI:18242 biolink:ChemicalSubstance cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18242 CHEBI:57808 biolink:ChemicalSubstance xanthommatin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57808 chebi_ph7_3 CHEBI:57809 biolink:ChemicalSubstance N-formyl-L-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57809 chebi_ph7_3 CHEBI:57806 biolink:ChemicalSubstance UDP-N-acetyl-D-galactosamine 4,6-bissulfate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57806 chebi_ph7_3 CHEBI:57807 biolink:ChemicalSubstance UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57807 chebi_ph7_3 CHEBI:82848 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82848 CHEBI:57804 biolink:ChemicalSubstance L-serine phosphoethanolamine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57804 chebi_ph7_3 CHEBI:57805 biolink:ChemicalSubstance N(2)-acetyl-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57805 chebi_ph7_3 CHEBI:82849 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82849 CHEBI:57803 biolink:ChemicalSubstance L-tryptophanamide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57803 chebi_ph7_3 CHEBI:33833 biolink:ChemicalSubstance heteroarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33833 CHEBI:67214 biolink:ChemicalSubstance 2'-deamino-2'-hydroxy-6'-dehydroparomamine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67214 chebi_ph7_3 CHEBI:82844 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-3-dehydro-alpha-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_82844 CHEBI:82845 biolink:ChemicalSubstance UDP-2,3-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82845 CHEBI:33835 biolink:ChemicalSubstance anthrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_33835 chebi_ph7_3 CHEBI:82842 biolink:ChemicalSubstance N-octanoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82842 chebi_ph7_3 CHEBI:33836 biolink:ChemicalSubstance benzenoid aromatic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33836 CHEBI:82840 biolink:ChemicalSubstance 1-oleoyl-2-myristoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82840 CHEBI:67210 biolink:ChemicalSubstance beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67210 chebi_ph7_3 CHEBI:33837 biolink:ChemicalSubstance conjugated protein go-plus.json http://purl.obolibrary.org/obo/CHEBI_33837 CHEBI:82841 biolink:ChemicalSubstance N-octanoyldihydrosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82841 chebi_ph7_3 CHEBI:67211 biolink:ChemicalSubstance beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67211 chebi_ph7_3 CHEBI:33838 biolink:ChemicalSubstance nucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_33838 chebi_ph7_3 CHEBI:67212 biolink:ChemicalSubstance [beta-D-Galf-(1->5)-beta-D-Galf-(1->6)]14-beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67212 chebi_ph7_3 CHEBI:33839 biolink:ChemicalSubstance macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_33839 CHEBI:67213 biolink:ChemicalSubstance 2'-deamino-2'-hydroxyneamine(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67213 chebi_ph7_3 CHEBI:33830 biolink:ChemicalSubstance galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33830 CHEBI:33832 biolink:ChemicalSubstance organic cyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33832 CHEBI:57800 biolink:ChemicalSubstance 3-ADP-glycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57800 chebi_ph7_3 CHEBI:57801 biolink:ChemicalSubstance cyclotriphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57801 chebi_ph7_3 CHEBI:67225 biolink:ChemicalSubstance 2'-deamino-2'-hydroxy-6'-dehydroparomamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67225 CHEBI:33845 biolink:ChemicalSubstance xylonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33845 CHEBI:67227 biolink:ChemicalSubstance beta-carotene 15,15'-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_67227 chebi_ph7_3 CHEBI:67228 biolink:ChemicalSubstance 15,15'-dihydroxy-beta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_67228 chebi_ph7_3 CHEBI:33847 biolink:ChemicalSubstance monocyclic arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33847 CHEBI:33848 biolink:ChemicalSubstance polycyclic arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33848 CHEBI:82852 biolink:ChemicalSubstance inosine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82852 chebi_ph7_3 CHEBI:67223 biolink:ChemicalSubstance 2'-deamino-2'-hydroxyneamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67223 CHEBI:82850 biolink:ChemicalSubstance 7-cyano-7-carbaguanine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82850 chebi_ph7_3 CHEBI:33842 biolink:ChemicalSubstance aromatic annulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33842 CHEBI:33843 biolink:ChemicalSubstance arabinonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33843 PR:000018721 biolink:Protein tumor necrosis factor ligand superfamily member 11 proteolytic cleavage product A tumor necrosis factor ligand superfamily member 11 that has been processed by proteolytic cleavage. go-plus.json TNFSF11/ClvPrd http://purl.obolibrary.org/obo/PR_000018721 CHEBI:82869 biolink:ChemicalSubstance (24S)-24-hydroxycholesterol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_82869 chebi_ph7_3 CHEBI:67237 biolink:ChemicalSubstance (22R)-22-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67237 chebi_ph7_3 CHEBI:33812 biolink:ChemicalSubstance galacturonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33812 CHEBI:67239 biolink:ChemicalSubstance EC 3.2.1.20 (alpha-glucosidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_67239 CHEBI:18218 biolink:ChemicalSubstance 2'-hydroxybiphenyl-2-sulfinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18218 chebi_ph7_3 CHEBI:18216 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18216 CHEBI:18217 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_18217 chebi_ph7_3 CHEBI:18215 biolink:ChemicalSubstance syringetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18215 CHEBI:18212 biolink:ChemicalSubstance selenite(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18212 chebi_ph7_3 CHEBI:18210 biolink:ChemicalSubstance hyponitrite(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18210 CHEBI:18211 biolink:ChemicalSubstance citrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_18211 CHEBI:67241 biolink:ChemicalSubstance beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67241 PR:000018718 biolink:Protein C-C motif chemokine 5 proteolytic cleavage product A C-C motif chemokine 5 that has been processed by proteolytic cleavage. go-plus.json CCL5/ClvPrd http://purl.obolibrary.org/obo/PR_000018718 CHEBI:67247 biolink:ChemicalSubstance (+)-secoisolariciresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67247 chebi_ph7_3 CHEBI:33822 biolink:ChemicalSubstance organic hydroxy compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33822 CHEBI:67248 biolink:ChemicalSubstance 4-(3-methylbut-2-enyl)-L-abrine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_67248 chebi_ph7_3 CHEBI:33823 biolink:ChemicalSubstance enol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33823 chebi_ph7_3 CHEBI:82875 biolink:ChemicalSubstance (24S)-24-hydroxycholesterol 3-linoleoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82875 chebi_ph7_3 CHEBI:67244 biolink:ChemicalSubstance (-)-lariciresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67244 chebi_ph7_3 CHEBI:67245 biolink:ChemicalSubstance (-)-pinoresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67245 chebi_ph7_3 CHEBI:33828 biolink:ChemicalSubstance xylonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33828 CHEBI:67246 biolink:ChemicalSubstance (+)-lariciresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67246 chebi_ph7_3 CHEBI:18209 biolink:ChemicalSubstance CoM-S-S-CoB go-plus.json http://purl.obolibrary.org/obo/CHEBI_18209 CHEBI:18207 biolink:ChemicalSubstance N-acetyl-D-galactosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18207 CHEBI:18208 biolink:ChemicalSubstance benzylpenicillin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18208 CHEBI:18205 biolink:ChemicalSubstance alpha-D-mannose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18205 CHEBI:33820 biolink:ChemicalSubstance iduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33820 CHEBI:18206 biolink:ChemicalSubstance 2-amino-5-oxocyclohex-1-enecarbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_18206 CHEBI:33821 biolink:ChemicalSubstance mannuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33821 CHEBI:18203 biolink:ChemicalSubstance penicillin N go-plus.json http://purl.obolibrary.org/obo/CHEBI_18203 CHEBI:18204 biolink:ChemicalSubstance 16,17-didehydroprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18204 chebi_ph7_3 CHEBI:18202 biolink:ChemicalSubstance L-iditol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18202 chebi_ph7_3 CHEBI:18200 biolink:ChemicalSubstance isoscoparin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18200 GO:0030417 biolink:BiologicalProcess nicotianamine metabolic process The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid. go-plus.json nicotianamine metabolism http://purl.obolibrary.org/obo/GO_0030417 GO:0030418 biolink:BiologicalProcess nicotianamine biosynthetic process The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid. go-plus.json nicotianamine anabolism|nicotianamine biosynthesis|nicotianamine synthesis|nicotianamine formation http://purl.obolibrary.org/obo/GO_0030418 GO:0005459 biolink:MolecularActivity UDP-galactose transmembrane transporter activity Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate. Reactome:R-HSA-735702|Reactome:R-HSA-5652099 go-plus.json http://purl.obolibrary.org/obo/GO_0005459 GO:0030415 biolink:MolecularActivity obsolete carboxypeptidase A inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the enzyme carboxypeptidase A. go-plus.json carboxypeptidase A inhibitor activity http://purl.obolibrary.org/obo/GO_0030415 GO:0030416 biolink:BiologicalProcess methylamine metabolic process The chemical reactions and pathways involving methylamine (CH3NH2). go-plus.json methylammonium metabolism|methylammonium metabolic process|methylamine metabolism http://purl.obolibrary.org/obo/GO_0030416 GO:0005457 biolink:MolecularActivity GDP-fucose transmembrane transporter activity Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. Reactome:R-HSA-742345|Reactome:R-HSA-5653596 go-plus.json http://purl.obolibrary.org/obo/GO_0005457 GO:0030413 biolink:MolecularActivity competence pheromone activity A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence. go-plus.json http://purl.obolibrary.org/obo/GO_0030413 GO:0005458 biolink:MolecularActivity GDP-mannose transmembrane transporter activity Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0005458 GO:0030414 biolink:MolecularActivity peptidase inhibitor activity Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. go-plus.json protease inhibitor activity http://purl.obolibrary.org/obo/GO_0030414 GO:0030411 biolink:MolecularActivity scytalone dehydratase activity Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O. EC:4.2.1.94|RHEA:24396|KEGG_REACTION:R02907|MetaCyc:SCYTALONE-DEHYDRATASE-RXN go-plus.json scytalone 7,8-hydro-lyase activity|scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) http://purl.obolibrary.org/obo/GO_0030411 GO:0030412 biolink:MolecularActivity formimidoyltetrahydrofolate cyclodeaminase activity Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+). EC:4.3.1.4|Reactome:R-HSA-70920|RHEA:22736|KEGG_REACTION:R02302|MetaCyc:4.3.1.4-RXN go-plus.json 5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)|5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)|formiminotetrahydrofolate cyclodeaminase activity http://purl.obolibrary.org/obo/GO_0030412 GO:0005456 biolink:MolecularActivity CMP-N-acetylneuraminate transmembrane transporter activity Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other. Reactome:R-HSA-727807|Reactome:R-HSA-5651942 go-plus.json CMP-sialic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005456 GO:0005453 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005453 GO:0005454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005454 GO:0005451 biolink:MolecularActivity monovalent cation:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out). Reactome:R-HSA-2889070 go-plus.json monovalent cation:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0005451 GO:0005452 biolink:MolecularActivity inorganic anion exchanger activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out). Reactome:R-HSA-425577|Reactome:R-HSA-427666|Reactome:R-HSA-425482|Reactome:R-HSA-5656248|Reactome:R-HSA-5627737|Reactome:R-HSA-1247665|Reactome:R-HSA-1237038 go-plus.json http://purl.obolibrary.org/obo/GO_0005452 GO:0030419 biolink:BiologicalProcess nicotianamine catabolic process The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid. go-plus.json nicotianamine breakdown|nicotianamine catabolism|nicotianamine degradation http://purl.obolibrary.org/obo/GO_0030419 GO:0030410 biolink:MolecularActivity nicotianamine synthase activity Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine. KEGG_REACTION:R00075|RHEA:16481|MetaCyc:2.5.1.43-RXN|EC:2.5.1.43 go-plus.json S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity http://purl.obolibrary.org/obo/GO_0030410 GO:0030406 biolink:MolecularActivity obsolete matrix metalloproteinase 25 activity OBSOLETE. Was not defined before being made obsolete. go-plus.json MT6-MMP|matrix metalloproteinase 25 activity|MMP-25 http://purl.obolibrary.org/obo/GO_0030406 GO:0030407 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030407 GO:0030404 biolink:MolecularActivity obsolete collagenase 3 activity OBSOLETE. Was not defined before being made obsolete. go-plus.json matrix metalloproteinase 13|collagenase 3 activity|MMP-13 http://purl.obolibrary.org/obo/GO_0030404 GO:0030405 biolink:MolecularActivity obsolete matrix metalloproteinase 19 activity OBSOLETE. Was not defined before being made obsolete. go-plus.json MMP-19|matrix metalloproteinase 19 activity http://purl.obolibrary.org/obo/GO_0030405 GO:0005468 biolink:MolecularActivity obsolete small-molecule carrier or transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json small-molecule carrier or transporter http://purl.obolibrary.org/obo/GO_0005468 GO:0030402 biolink:MolecularActivity obsolete matrilysin-2 activity OBSOLETE. Was not defined before being made obsolete. go-plus.json matrilysin-2 activity|matrix metalloproteinase 26|MMP-26 http://purl.obolibrary.org/obo/GO_0030402 GO:0005469 biolink:MolecularActivity succinate:fumarate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out). go-plus.json http://purl.obolibrary.org/obo/GO_0005469 GO:0030403 biolink:MolecularActivity obsolete collagenase 4 activity OBSOLETE. Was not defined before being made obsolete. go-plus.json matrix metalloproteinase 18|MMP-18|collagenase 4 activity http://purl.obolibrary.org/obo/GO_0030403 GO:0030400 biolink:MolecularActivity obsolete protease substrate recruitment factor activity OBSOLETE. A recruiting factor or adaptor molecule associated with the proteasome that activates degradation of specific proteasomal substrates and links them to the degradation machinery; it is not involved in ubiquitination; does not possess proteolytic activity. go-plus.json protease substrate recruitment factor activity http://purl.obolibrary.org/obo/GO_0030400 GO:0030401 biolink:MolecularActivity obsolete transcription antiterminator activity OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed. go-plus.json transcription antiterminator activity|transcriptional antiterminator activity http://purl.obolibrary.org/obo/GO_0030401 GO:0005464 biolink:MolecularActivity UDP-xylose transmembrane transporter activity Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate. Reactome:R-HSA-742373 go-plus.json http://purl.obolibrary.org/obo/GO_0005464 GO:0005462 biolink:MolecularActivity UDP-N-acetylglucosamine transmembrane transporter activity Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. Reactome:R-HSA-5653622|Reactome:R-HSA-741450|Reactome:R-HSA-742354 go-plus.json http://purl.obolibrary.org/obo/GO_0005462 GO:0005463 biolink:MolecularActivity UDP-N-acetylgalactosamine transmembrane transporter activity Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0005463 GO:0005460 biolink:MolecularActivity UDP-glucose transmembrane transporter activity Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0005460 GO:0005461 biolink:MolecularActivity UDP-glucuronic acid transmembrane transporter activity Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. Reactome:R-HSA-174368|Reactome:R-HSA-5603297 go-plus.json http://purl.obolibrary.org/obo/GO_0005461 GO:0030408 biolink:MolecularActivity glycine formimidoyltransferase activity Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine. KEGG_REACTION:R02729|MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN|RHEA:24288|EC:2.1.2.4 go-plus.json formiminotransferase activity|5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity|formimidoyltransferase activity|glycine formiminotransferase activity|FIG formiminotransferase activity|formiminoglycine formiminotransferase activity http://purl.obolibrary.org/obo/GO_0030408 GO:0030409 biolink:MolecularActivity glutamate formimidoyltransferase activity Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate. MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN|EC:2.1.2.5|RHEA:15097 go-plus.json formiminoglutamic acid transferase activity|formiminoglutamic formiminotransferase activity|formiminotransferase activity|formimidoyltransferase activity|glutamate formiminotransferase activity|5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity|glutamate formyltransferase activity http://purl.obolibrary.org/obo/GO_0030409 CHEBI:5613 biolink:ChemicalSubstance haloperidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_5613 CHEBI:5610 biolink:ChemicalSubstance haloalkene go-plus.json http://purl.obolibrary.org/obo/CHEBI_5610 GO:0005436 biolink:MolecularActivity sodium:phosphate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in). Reactome:R-HSA-427656|Reactome:R-HSA-2872498|Reactome:R-HSA-5625123|Reactome:R-HSA-428609|Reactome:R-HSA-5687585|Reactome:R-HSA-427645|Reactome:R-HSA-5651685|Reactome:R-HSA-5651697|Reactome:R-HSA-5651971|Reactome:R-HSA-427605 go-plus.json sodium/phosphate symporter activity|sodium-dependent phosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005436 GO:0005432 biolink:MolecularActivity calcium:sodium antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in). Reactome:R-HSA-8949688|Reactome:R-HSA-8949703|Reactome:R-HSA-425661|RHEA:29255 go-plus.json sodium:calcium exchange|mitochondrial sodium/calcium ion exchange|sodium/calcium exchanger http://purl.obolibrary.org/obo/GO_0005432 GO:0005430 biolink:MolecularActivity obsolete synaptic vesicle amine transmembrane transporter activity OBSOLETE. Enables the transfer of amines across synaptic vesicle membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0005430 CHEBI:43254 biolink:ChemicalSubstance (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_43254 chebi_ph7_3 CHEBI:57891 biolink:ChemicalSubstance trans-2-chloro-4-carboxylatomethylenebut-2-en-1,4-olide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57891 chebi_ph7_3 CHEBI:57892 biolink:ChemicalSubstance 3-(dioxido-lambda(5)-azanylidene)propanoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57892 CHEBI:57890 biolink:ChemicalSubstance adenosine 5'-phosphoramidate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57890 chebi_ph7_3 CHEBI:57899 biolink:ChemicalSubstance 15,16-dihydrobiliverdin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57899 chebi_ph7_3 CHEBI:57897 biolink:ChemicalSubstance 1-phosphonato-alpha-D-glucuronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57897 chebi_ph7_3 CHEBI:57895 biolink:ChemicalSubstance 1D-myo-inositol 1,3,4,5-tetrakisphosphate(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57895 chebi_ph7_3 CHEBI:57896 biolink:ChemicalSubstance diisopropyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57896 chebi_ph7_3 CHEBI:57893 biolink:ChemicalSubstance tabersoninium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57893 chebi_ph7_3 CHEBI:57894 biolink:ChemicalSubstance berbamuninium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57894 chebi_ph7_3 CHEBI:18283 biolink:ChemicalSubstance alpha,alpha-trehalose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18283 CHEBI:18284 biolink:ChemicalSubstance thiamine(1+) triphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18284 GO:0005415 biolink:MolecularActivity nucleoside:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in). Reactome:R-HSA-109530|Reactome:R-HSA-109538|Reactome:R-HSA-109539 go-plus.json sodium-dependent nucleoside transporter activity|nucleoside-sodium cotransporter activity http://purl.obolibrary.org/obo/GO_0005415 CHEBI:18281 biolink:ChemicalSubstance 2,5-didehydro-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18281 GO:0005416 biolink:MolecularActivity amino acid:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in). go-plus.json cation/amino acid symporter activity|cation:amino acid symporter activity http://purl.obolibrary.org/obo/GO_0005416 CHEBI:18282 biolink:ChemicalSubstance nucleobase go-plus.json http://purl.obolibrary.org/obo/CHEBI_18282 CHEBI:18280 biolink:ChemicalSubstance phenylglyoxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18280 GO:0005412 biolink:MolecularActivity glucose:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). Reactome:R-HSA-189208|Reactome:R-HSA-5656356|Reactome:R-HSA-8932955|Reactome:R-HSA-429613|Reactome:R-HSA-5658163 go-plus.json sodium/glucose symporter activity http://purl.obolibrary.org/obo/GO_0005412 CHEBI:57880 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57880 chebi_ph7_3 CHEBI:57888 biolink:ChemicalSubstance 4-carboxylatomethyl-4-methylbut-2-en-1,4-olide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57888 chebi_ph7_3 CHEBI:57889 biolink:ChemicalSubstance N(5)-(L-1-carboxyethyl)-L-ornithine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57889 chebi_ph7_3 CHEBI:57886 biolink:ChemicalSubstance 2'-deoxy-5-methyl-5'-cytidylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57886 chebi_ph7_3 CHEBI:18278 biolink:ChemicalSubstance N-acetyl-D-glucosaminyldiphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18278 CHEBI:57887 biolink:ChemicalSubstance tryptaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57887 chebi_ph7_3 CHEBI:18276 biolink:ChemicalSubstance dihydrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_18276 chebi_ph7_3 CHEBI:57885 biolink:ChemicalSubstance 3-dehydrocarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57885 chebi_ph7_3 CHEBI:18277 biolink:ChemicalSubstance N-(5-phosphonato-beta-D-ribosyl)anthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18277 chebi_ph7_3 CHEBI:18274 biolink:ChemicalSubstance 2'-deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_18274 chebi_ph7_3 CHEBI:57882 biolink:ChemicalSubstance erythro-5-phosphonatoooxy-L-lysinium(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57882 chebi_ph7_3 CHEBI:57883 biolink:ChemicalSubstance 4-carboxylatomethyl-3-methylbut-2-en-1,4-olide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57883 chebi_ph7_3 CHEBI:18272 biolink:ChemicalSubstance N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18272 GO:0005429 biolink:MolecularActivity obsolete chromaffin granule amine transmembrane transporter activity OBSOLETE. Enables the transfer of amines across chromaffin granule membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0005429 GO:0005427 biolink:MolecularActivity proton-dependent oligopeptide secondary active transmembrane transporter activity Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement. go-plus.json proton-dependent oligopeptide transporter activity|hydrogen/oligopeptide symporter http://purl.obolibrary.org/obo/GO_0005427 CHEBI:18271 biolink:ChemicalSubstance 2',3'-cyclic nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18271 NCBITaxon:88036 biolink:OrganismalEntity Selaginella moellendorffii go-plus.json Selaginella moellendorfii http://purl.obolibrary.org/obo/NCBITaxon_88036 CHEBI:57879 biolink:ChemicalSubstance 4-methylene-L-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57879 chebi_ph7_3 OBA:VT0001614 biolink:OntologyClass blood vessel morphology trait The morphology of a blood vessel. go-plus.json morphology of blood vessel http://purl.obolibrary.org/obo/OBA_VT0001614 CHEBI:57870 biolink:ChemicalSubstance D-ribulose 1,5-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57870 chebi_ph7_3 CHEBI:57877 biolink:ChemicalSubstance N-acetyl-D-tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57877 chebi_ph7_3 CHEBI:18269 biolink:ChemicalSubstance (1->6)-alpha-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_18269 chebi_ph7_3 CHEBI:57878 biolink:ChemicalSubstance 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronate)-6-O-sulfonato-D-galactopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57878 chebi_ph7_3 CHEBI:18267 biolink:ChemicalSubstance 5-oxo-4,5-dihydro-2-furylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18267 CHEBI:57875 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57875 chebi_ph7_3 CHEBI:57876 biolink:ChemicalSubstance CDP-ethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57876 chebi_ph7_3 CHEBI:18268 biolink:ChemicalSubstance D-glucurono-6,3-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18268 chebi_ph7_3 CHEBI:18265 biolink:ChemicalSubstance 2-aminopteridin-4-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18265 chebi_ph7_3 CHEBI:57873 biolink:ChemicalSubstance (S)-reticulinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57873 chebi_ph7_3 CHEBI:5653 biolink:ChemicalSubstance hemiacetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_5653 CHEBI:18266 biolink:ChemicalSubstance 1D-4-O-methyl-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18266 chebi_ph7_3 CHEBI:18263 biolink:ChemicalSubstance 1-(5-phospho-D-ribosyl)-ATP go-plus.json http://purl.obolibrary.org/obo/CHEBI_18263 CHEBI:57871 biolink:ChemicalSubstance codeine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57871 chebi_ph7_3 CHEBI:57872 biolink:ChemicalSubstance (Z)-but-2-ene-1,2,3-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57872 chebi_ph7_3 CHEBI:57868 biolink:ChemicalSubstance N-sulfo-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57868 chebi_ph7_3 CHEBI:57869 biolink:ChemicalSubstance 6-aminopenicillanic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57869 chebi_ph7_3 CHEBI:33899 biolink:ChemicalSubstance tagaturonic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_33899 NCBITaxon:64091 biolink:OrganismalEntity Halobacterium salinarum NRC-1 go-plus.json Halobacterium salinarum strain NRC-1|Halobacterium sp. ATCC 700922|Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081)|Halobacterium sp. NRC-1|Halobacterium sp. JCM 11081|Halobacterium halobium NRC-1|Halobacterium salinarum str. NRC-1|Halobacterium sp. (strain NRC-1) http://purl.obolibrary.org/obo/NCBITaxon_64091 CHEBI:33892 biolink:ChemicalSubstance iron coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33892 CHEBI:33893 biolink:ChemicalSubstance reagent go-plus.json http://purl.obolibrary.org/obo/CHEBI_33893 CHEBI:33897 biolink:ChemicalSubstance iduronic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_33897 CHEBI:33898 biolink:ChemicalSubstance mannuronic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_33898 CHEBI:57866 biolink:ChemicalSubstance 3-methylthiopropylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57866 chebi_ph7_3 CHEBI:57867 biolink:ChemicalSubstance nucleoside 5'-phosphate dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57867 chebi_ph7_3 CHEBI:57864 biolink:ChemicalSubstance (4S,5S)-5-hydroxy-4-(hydroxymethyl)-6-oxocyclohex-1-en-1-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57864 CHEBI:57865 biolink:ChemicalSubstance uridine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57865 chebi_ph7_3 CHEBI:18298 biolink:ChemicalSubstance 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18298 chebi_ph7_3 CHEBI:57862 biolink:ChemicalSubstance diphthamide(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_57862 chebi_ph7_3 CHEBI:57863 biolink:ChemicalSubstance ADP-D-glycero-D-manno-heptose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57863 chebi_ph7_3 CHEBI:18299 biolink:ChemicalSubstance 1-C-(indol-3-yl)glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18299 CHEBI:18296 biolink:ChemicalSubstance chondroitin 6'-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18296 CHEBI:18297 biolink:ChemicalSubstance 1D-myo-inositol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18297 CHEBI:57861 biolink:ChemicalSubstance dethiobiotin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57861 chebi_ph7_3 CHEBI:33890 biolink:ChemicalSubstance cobalt coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33890 CHEBI:18295 biolink:ChemicalSubstance histamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18295 CHEBI:18292 biolink:ChemicalSubstance jasmonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18292 CHEBI:18293 biolink:ChemicalSubstance 5-methoxypsoralen go-plus.json http://purl.obolibrary.org/obo/CHEBI_18293 chebi_ph7_3 CHEBI:57859 biolink:ChemicalSubstance 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57859 chebi_ph7_3 GO:0005402 biolink:MolecularActivity carbohydrate:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in). go-plus.json cation:sugar symporter activity|sugar:cation symporter activity|cation/sugar symporter activity http://purl.obolibrary.org/obo/GO_0005402 CHEBI:18291 biolink:ChemicalSubstance manganese atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_18291 chebi_ph7_3 GO:0005403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005403 CHEBI:57857 biolink:ChemicalSubstance N-acetyl-beta-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57857 chebi_ph7_3 GO:0005400 biolink:MolecularActivity obsolete peroxisomal membrane transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json peroxisomal membrane transporter http://purl.obolibrary.org/obo/GO_0005400 CHEBI:57858 biolink:ChemicalSubstance atropinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57858 chebi_ph7_3 CHEBI:57855 biolink:ChemicalSubstance protochlorophyllide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57855 CHEBI:57856 biolink:ChemicalSubstance S-adenosyl-L-homocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57856 chebi_ph7_3 CHEBI:57853 biolink:ChemicalSubstance hypotaurine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57853 chebi_ph7_3 CHEBI:18289 biolink:ChemicalSubstance quinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_18289 chebi_ph7_3 CHEBI:57854 biolink:ChemicalSubstance 4-guanidiniumylbutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_57854 chebi_ph7_3 CHEBI:57851 biolink:ChemicalSubstance tropiniumone go-plus.json http://purl.obolibrary.org/obo/CHEBI_57851 chebi_ph7_3 CHEBI:18287 biolink:ChemicalSubstance L-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18287 CHEBI:57852 biolink:ChemicalSubstance prephenate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57852 chebi_ph7_3 CHEBI:18288 biolink:ChemicalSubstance (S)-2-hydroxypropyl-CoM go-plus.json http://purl.obolibrary.org/obo/CHEBI_18288 CHEBI:18285 biolink:ChemicalSubstance (S)-stylopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18285 chebi_ph7_3 CHEBI:57850 biolink:ChemicalSubstance 3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronate)-D-galactosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57850 chebi_ph7_3 CHEBI:149484 biolink:ChemicalSubstance chloroquine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149484 chebi_ph7_3 CHEBI:5445 biolink:ChemicalSubstance glyceraldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_5445 chebi_ph7_3 NCBITaxon:1476529 biolink:OrganismalEntity Cyclostomata go-plus.json Agnatha|jawless vertebrates http://purl.obolibrary.org/obo/NCBITaxon_1476529 CHEBI:5457 biolink:ChemicalSubstance glycerophosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_5457 GO:0030598 biolink:MolecularActivity rRNA N-glycosylase activity Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species. EC:3.2.2.22|MetaCyc:3.2.2.22-RXN go-plus.json gelonin|ricin|mirabilis antiviral protein|nigrin b|rRNA N-glycohydrolase activity|momorcochin-S|saporins|RNA N-glycosidase activity|ribosomal ribonucleate N-glycosidase activity|rRNA N-glycosidase activity http://purl.obolibrary.org/obo/GO_0030598 GO:0030599 biolink:MolecularActivity pectinesterase activity Catalysis of the reaction: pectin + n H2O = n methanol + pectate. EC:3.1.1.11|RHEA:22380|MetaCyc:PECTINESTERASE-RXN go-plus.json pectinoesterase activity|pectin pectylhydrolase activity|pectin methyl esterase activity|pectase activity|pectin methylesterase activity|pectin demethoxylase activity|pectin methoxylase activity http://purl.obolibrary.org/obo/GO_0030599 CHEBI:149465 biolink:ChemicalSubstance glucopentaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_149465 GO:0030596 biolink:MolecularActivity alpha-L-rhamnosidase activity Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides. EC:3.2.1.40|MetaCyc:3.2.1.40-RXN go-plus.json alpha-L-rhamnoside rhamnohydrolase activity|alpha-L-rhamnosidase T|alpha-L-rhamnosidase N http://purl.obolibrary.org/obo/GO_0030596 GO:0030597 biolink:MolecularActivity RNA glycosylase activity Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0030597 GO:0030594 biolink:MolecularActivity neurotransmitter receptor activity Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0030594 GO:0030595 biolink:BiologicalProcess leukocyte chemotaxis The movement of a leukocyte in response to an external stimulus. go-plus.json leucocyte chemotaxis|immune cell chemotaxis http://purl.obolibrary.org/obo/GO_0030595 GO:0030592 biolink:BiologicalProcess DNA ADP-ribosylation The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0030592 GO:0030593 biolink:BiologicalProcess neutrophil chemotaxis The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0030593 GO:0030590 biolink:BiologicalProcess first cell cycle pseudocleavage A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms. go-plus.json http://purl.obolibrary.org/obo/GO_0030590 GO:0030591 biolink:MolecularActivity 2'-deoxyguanosine DNA ADP-ribosyltransferase activity Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form. go-plus.json NAD DNA ADP-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0030591 GO:0030589 biolink:BiologicalProcess pseudocleavage involved in syncytial blastoderm formation Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster. go-plus.json pseudocleavage during syncytial blastoderm formation http://purl.obolibrary.org/obo/GO_0030589 GO:0030587 biolink:BiologicalProcess sorocarp development The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum. go-plus.json fruiting body development|fruiting body formation|sorocarp biosynthesis|sorocarp formation http://purl.obolibrary.org/obo/GO_0030587 GO:0030588 biolink:BiologicalProcess pseudocleavage Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0030588 CHEBI:5435 biolink:ChemicalSubstance piperidine-2,6-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_5435 chebi_ph7_3 GO:0030585 biolink:MolecularActivity phosphoenolpyruvate carboxykinase (diphosphate) activity Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate. EC:4.1.1.38|KEGG_REACTION:R00346|RHEA:22356|MetaCyc:4.1.1.38-RXN go-plus.json phosphoenolpyruvate carboxylase (pyrophosphate)|PEPCTrP|phosphoenolpyruvic carboxytransphosphorylase activity|phosphoenolpyruvate carboxykinase (pyrophosphate) activity|phosphopyruvate carboxylase (pyrophosphate)|phosphoenolpyruvic carboxylase (pyrophosphate)|PEP carboxyphosphotransferase activity|phosphoenolpyruvate carboxytransphosphorylase activity|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)|phosphoenolpyruvic carboxykinase (pyrophosphate)|phosphopyruvate carboxykinase (pyrophosphate)|phosphoenolpyruvic carboxykinase|phosphopyruvate carboxykinase|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphoenolpyruvate carboxyphosphotransferase activity http://purl.obolibrary.org/obo/GO_0030585 GO:0030586 biolink:MolecularActivity [methionine synthase] reductase activity Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+. Reactome:R-HSA-3149518|RHEA:23908|EC:1.16.1.8|MetaCyc:2.1.1.135-RXN go-plus.json methionine synthase reductase activity|methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)|[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity|methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity|methionine synthase cob(II)alamin reductase (methylating) activity|5-methyltetrahydrofolate-homocysteine methyltransferase reductase http://purl.obolibrary.org/obo/GO_0030586 GO:0030583 biolink:BiologicalProcess myxococcal fruiting body development The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure. go-plus.json fruiting body development in cellular response to starvation|fruiting body development in response to starvation http://purl.obolibrary.org/obo/GO_0030583 GO:0030584 biolink:BiologicalProcess sporocarp development The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea. go-plus.json fruiting body development http://purl.obolibrary.org/obo/GO_0030584 GO:0030581 biolink:BiologicalProcess symbiont intracellular protein transport in host The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json intracellular protein transport in other organism involved in symbiotic interaction|intracellular protein transport in other organism during symbiotic interaction|intracellular protein transport in host|host cell protein transport http://purl.obolibrary.org/obo/GO_0030581 GO:0030582 biolink:BiologicalProcess reproductive fruiting body development The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores. go-plus.json fruiting body formation http://purl.obolibrary.org/obo/GO_0030582 GO:0030580 biolink:MolecularActivity quinone cofactor methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1). go-plus.json http://purl.obolibrary.org/obo/GO_0030580 GO:0030578 biolink:BiologicalProcess PML body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia). go-plus.json PML body organisation|PML body organization and biogenesis http://purl.obolibrary.org/obo/GO_0030578 GO:0030579 biolink:BiologicalProcess ubiquitin-dependent SMAD protein catabolic process The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome. go-plus.json ubiquitin-dependent SMAD protein catabolism|ubiquitin-dependent SMAD protein degradation|ubiquitin-dependent SMAD protein breakdown http://purl.obolibrary.org/obo/GO_0030579 GO:0030576 biolink:BiologicalProcess Cajal body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors. go-plus.json Cajal body organisation|Cajal body organization and biogenesis http://purl.obolibrary.org/obo/GO_0030576 GO:0030577 biolink:BiologicalProcess Lands organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies. go-plus.json Lands organization and biogenesis|Lands organisation|LYSP100-associated nuclear domain organization http://purl.obolibrary.org/obo/GO_0030577 GO:0030574 biolink:BiologicalProcess collagen catabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. go-plus.json collagen catabolism|collagen degradation|collagen breakdown http://purl.obolibrary.org/obo/GO_0030574 GO:0030575 biolink:BiologicalProcess nuclear body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. go-plus.json nuclear body organization and biogenesis|nuclear body organisation http://purl.obolibrary.org/obo/GO_0030575 GO:0030572 biolink:MolecularActivity phosphatidyltransferase activity Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group. go-plus.json http://purl.obolibrary.org/obo/GO_0030572 GO:0030573 biolink:BiologicalProcess bile acid catabolic process The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. MetaCyc:7ALPHADEHYDROX-PWY go-plus.json bile acid catabolism|cholate catabolic process|bile acid 7alpha-dehydroxylation pathway|bile acid degradation|bile acid breakdown http://purl.obolibrary.org/obo/GO_0030573 GO:0030570 biolink:MolecularActivity pectate lyase activity Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. MetaCyc:4.2.2.2-RXN|EC:4.2.2.2 go-plus.json endo-alpha-1,4-polygalacturonic acid lyase activity|(1->4)-alpha-D-galacturonan lyase activity|pectic lyase activity|pectin trans-eliminase activity|pectate transeliminase activity|polygalacturonate lyase activity|PGA lyase activity|PPase-N activity|polygalacturonic transeliminase activity|polygalacturonic acid trans-eliminase activity|endogalacturonate transeliminase activity|endopectin methyltranseliminase activity|pectic acid transeliminase activity|alpha-1,4-D-endopolygalacturonic acid lyase activity|polygalacturonic acid lyase activity|pectic acid lyase activity http://purl.obolibrary.org/obo/GO_0030570 GO:0030571 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030571 GO:0030569 biolink:MolecularActivity obsolete chymotrypsin inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin. go-plus.json chymotrypsin inhibitor activity http://purl.obolibrary.org/obo/GO_0030569 GO:0030567 biolink:MolecularActivity obsolete thrombin activator activity OBSOLETE. Increases the rate of proteolysis catalyzed by thrombin. go-plus.json prothrombin activator activity|thrombin activator activity http://purl.obolibrary.org/obo/GO_0030567 GO:0030568 biolink:MolecularActivity obsolete plasmin inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase plasmin. go-plus.json plasmin inhibitor activity http://purl.obolibrary.org/obo/GO_0030568 GO:0030565 biolink:MolecularActivity snRNA pseudouridylation guide activity Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0030565 GO:0030566 biolink:MolecularActivity snRNA modification guide activity Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030566 CHEBI:149433 biolink:ChemicalSubstance mannotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_149433 CHEBI:43197 biolink:ChemicalSubstance (R)-3-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43197 RO:0002598 biolink:OntologyClass capable of positively regulating Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. RO:0002598 go-plus.json http://purl.obolibrary.org/obo/RO_0002598 GO:0030563 biolink:MolecularActivity snRNA 2'-O-ribose methylation guide activity Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0030563 GO:0030564 biolink:MolecularActivity tRNA 2'-O-ribose methylation guide activity Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030564 GO:0030561 biolink:MolecularActivity RNA 2'-O-ribose methylation guide activity Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030561 GO:0030562 biolink:MolecularActivity rRNA 2'-O-ribose methylation guide activity Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030562 GO:0030560 biolink:MolecularActivity tRNA pseudouridylation guide activity Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030560 GO:0030558 biolink:MolecularActivity RNA pseudouridylation guide activity Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030558 GO:0030559 biolink:MolecularActivity rRNA pseudouridylation guide activity Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030559 GO:0030556 biolink:MolecularActivity rRNA modification guide activity Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030556 GO:0030557 biolink:MolecularActivity tRNA modification guide activity Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030557 GO:0030554 biolink:MolecularActivity adenyl nucleotide binding Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0030554 goslim_chembl GO:0005598 biolink:CellularComponent short-chain collagen trimer Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005598 GO:0030555 biolink:MolecularActivity RNA modification guide activity Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030555 goslim_yeast|goslim_generic GO:0005599 biolink:CellularComponent collagen type X trimer A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets). go-plus.json http://purl.obolibrary.org/obo/GO_0005599 CHEBI:149429 biolink:ChemicalSubstance xylotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_149429 GO:0005596 biolink:CellularComponent collagen type XIV trimer A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures. go-plus.json http://purl.obolibrary.org/obo/GO_0005596 RO:0002595 biolink:OntologyClass causal relation between material entity and a process A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. RO:0002595 go-plus.json http://purl.obolibrary.org/obo/RO_0002595 GO:0005597 biolink:CellularComponent collagen type XVI trimer A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005597 GO:0005594 biolink:CellularComponent collagen type IX trimer A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005594 RO:0002596 biolink:OntologyClass capable of regulating Holds between c and p if and only if c is capable of some activity a, and a regulates p. RO:0002596 go-plus.json http://purl.obolibrary.org/obo/RO_0002596 RO:0002597 biolink:OntologyClass capable of negatively regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. RO:0002597 go-plus.json http://purl.obolibrary.org/obo/RO_0002597 GO:0005595 biolink:CellularComponent collagen type XII trimer A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures. go-plus.json http://purl.obolibrary.org/obo/GO_0005595 GO:0005592 biolink:CellularComponent collagen type XI trimer A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005592 RO:0002590 biolink:OntologyClass results_in_disassembly_of RO:0002590 go-plus.json http://purl.obolibrary.org/obo/RO_0002590 GO:0005593 biolink:CellularComponent FACIT collagen trimer A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences. Wikipedia:FACIT_collagen go-plus.json http://purl.obolibrary.org/obo/GO_0005593 RO:0002591 biolink:OntologyClass results in remodeling of RO:0002591 go-plus.json http://purl.obolibrary.org/obo/RO_0002591 GO:0005590 biolink:CellularComponent collagen type VII trimer A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin. go-plus.json http://purl.obolibrary.org/obo/GO_0005590 CHEBI:43186 biolink:ChemicalSubstance 5-hydroxy-D-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_43186 RO:0002592 biolink:OntologyClass results in organization of p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c RO:0002592 go-plus.json http://purl.obolibrary.org/obo/RO_0002592 GO:0005591 biolink:CellularComponent collagen type VIII trimer A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets. go-plus.json http://purl.obolibrary.org/obo/GO_0005591 RO:0002588 biolink:OntologyClass results_in_assembly_of RO:0002588 go-plus.json http://purl.obolibrary.org/obo/RO_0002588 GO:0030552 biolink:MolecularActivity cAMP binding Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate). go-plus.json 3',5'-cAMP binding|adenosine 3',5'-cyclophosphate binding|cyclic AMP binding|3',5' cAMP binding http://purl.obolibrary.org/obo/GO_0030552 GO:0030553 biolink:MolecularActivity cGMP binding Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate). go-plus.json 3',5'-cGMP binding|cyclic GMP binding|3',5' cGMP binding http://purl.obolibrary.org/obo/GO_0030553 GO:0030550 biolink:MolecularActivity acetylcholine receptor inhibitor activity Binds to and stops, prevents or reduces the activity of an acetylcholine receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0030550 GO:0030551 biolink:MolecularActivity cyclic nucleotide binding Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. go-plus.json http://purl.obolibrary.org/obo/GO_0030551 GO:0030549 biolink:MolecularActivity acetylcholine receptor activator activity Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased. go-plus.json http://purl.obolibrary.org/obo/GO_0030549 GO:0030547 biolink:MolecularActivity signaling receptor inhibitor activity Binds to and modulates the activity of a signaling receptor. go-plus.json receptor inhibitor activity http://purl.obolibrary.org/obo/GO_0030547 GO:0030548 biolink:MolecularActivity acetylcholine receptor regulator activity Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed. go-plus.json http://purl.obolibrary.org/obo/GO_0030548 GO:0030545 biolink:MolecularActivity signaling receptor regulator activity Binds to and modulates the activity of a receptor. go-plus.json receptor regulator activity http://purl.obolibrary.org/obo/GO_0030545 GO:0030546 biolink:MolecularActivity signaling receptor activator activity The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased. go-plus.json signalling receptor activator activity|receptor activator activity http://purl.obolibrary.org/obo/GO_0030546 GO:0030543 biolink:BiologicalProcess 2-micrometer plasmid partitioning The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0030543 GO:0030544 biolink:MolecularActivity Hsp70 protein binding Binding to a Hsp70 protein, heat shock proteins around 70kDa in size. go-plus.json http://purl.obolibrary.org/obo/GO_0030544 RO:0002584 biolink:OntologyClass has part structure that is capable of s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p RO:0002584 go-plus.json http://purl.obolibrary.org/obo/RO_0002584 RO:0002586 biolink:OntologyClass results in breakdown of p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p RO:0002586 go-plus.json http://purl.obolibrary.org/obo/RO_0002586 CHEBI:43176 biolink:ChemicalSubstance hydroxy group go-plus.json http://purl.obolibrary.org/obo/CHEBI_43176 chebi_ph7_3 RO:0002576 biolink:OntologyClass RO:0002576 go-plus.json http://purl.obolibrary.org/obo/RO_0002576 RO:0002578 biolink:OntologyClass directly regulates Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. RO:0002578 go-plus.json http://purl.obolibrary.org/obo/RO_0002578 GO:0030541 biolink:BiologicalProcess plasmid partitioning Any process in which plasmids are segregated or distributed into daughter cells upon cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0030541 GO:0030542 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030542 GO:0030540 biolink:BiologicalProcess female genitalia development The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure. go-plus.json female genital development http://purl.obolibrary.org/obo/GO_0030540 CHEBI:67132 biolink:ChemicalSubstance ditrans,polycis-polyprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67132 chebi_ph7_3 CHEBI:82769 biolink:ChemicalSubstance caldopentamine(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82769 chebi_ph7_3 CHEBI:82767 biolink:ChemicalSubstance 4-(5-O-phosphonato-beta-D-ribofuranosyl)phenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82767 chebi_ph7_3 RO:0002572 biolink:OntologyClass RO:0002572 go-plus.json http://purl.obolibrary.org/obo/RO_0002572 CHEBI:67138 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-galactosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67138 chebi_ph7_3 CHEBI:82768 biolink:ChemicalSubstance caldopentamine(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82768 CHEBI:67139 biolink:ChemicalSubstance (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67139 chebi_ph7_3 CHEBI:82765 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycerol 3-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82765 chebi_ph7_3 CHEBI:82766 biolink:ChemicalSubstance 2-O-(alpha-D-glucopyranosyl)glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82766 chebi_ph7_3 CHEBI:82763 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82763 CHEBI:67133 biolink:ChemicalSubstance UDP-2-acetamido-4-azaniumyl-2,4,6-trideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67133 CHEBI:67134 biolink:ChemicalSubstance UDP-N,N'-diacetylbacillosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67134 chebi_ph7_3 CHEBI:82764 biolink:ChemicalSubstance O-[S-2-methylbutanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82764 chebi_ph7_3 CHEBI:67135 biolink:ChemicalSubstance 2-nitroimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_67135 chebi_ph7_3 CHEBI:67136 biolink:ChemicalSubstance cannabidiolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67136 chebi_ph7_3 RO:0002571 biolink:OntologyClass RO:0002571 go-plus.json http://purl.obolibrary.org/obo/RO_0002571 CHEBI:82762 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82762 RO:0002569 biolink:OntologyClass RO:0002569 go-plus.json http://purl.obolibrary.org/obo/RO_0002569 RO:0002565 biolink:OntologyClass results in movement of Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c RO:0002565 go-plus.json http://purl.obolibrary.org/obo/RO_0002565 RO:0002566 biolink:OntologyClass causally influences The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). RO:0002566 go-plus.json http://purl.obolibrary.org/obo/RO_0002566 RO:0002568 biolink:OntologyClass m1 has_muscle_antagonist m2 iff m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. RO:0002568 go-plus.json http://purl.obolibrary.org/obo/RO_0002568 CHEBI:546274 biolink:ChemicalSubstance (4-hydroxy-3-nitrophenyl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_546274 CHEBI:67140 biolink:ChemicalSubstance phosphate monoester dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_67140 chebi_ph7_3 CHEBI:33808 biolink:ChemicalSubstance galacturonic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_33808 CHEBI:67142 biolink:ChemicalSubstance nucleobase analogue go-plus.json http://purl.obolibrary.org/obo/CHEBI_67142 CHEBI:67143 biolink:ChemicalSubstance pppA2'p5'A2'p5'A go-plus.json http://purl.obolibrary.org/obo/CHEBI_67143 chebi_ph7_3 CHEBI:67148 biolink:ChemicalSubstance 2-hydroxybenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67148 chebi_ph7_3 CHEBI:33801 biolink:ChemicalSubstance D-glucarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33801 CHEBI:33804 biolink:ChemicalSubstance gluconates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33804 CHEBI:82774 biolink:ChemicalSubstance (R)-3,5-bisphosphonatomevalonate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82774 chebi_ph7_3 CHEBI:67145 biolink:ChemicalSubstance fumigaclavine A(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67145 chebi_ph7_3 CHEBI:82775 biolink:ChemicalSubstance 5'-deoxyinosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82775 chebi_ph7_3 CHEBI:33805 biolink:ChemicalSubstance 2-amino-2-deoxy-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33805 CHEBI:67146 biolink:ChemicalSubstance fumigaclavine B(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67146 chebi_ph7_3 CHEBI:82772 biolink:ChemicalSubstance N(4)-aminopropylspermine(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82772 chebi_ph7_3 CHEBI:67147 biolink:ChemicalSubstance fumigaclavine C(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67147 chebi_ph7_3 CHEBI:82773 biolink:ChemicalSubstance (R)-3-phosphonatomevalonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82773 chebi_ph7_3 CHEBI:82770 biolink:ChemicalSubstance N(4)-aminopropylspermidine(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82770 chebi_ph7_3 CHEBI:82771 biolink:ChemicalSubstance N(4)-bis(aminopropyl)spermidine(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82771 chebi_ph7_3 RO:0002559 biolink:OntologyClass causally influenced by RO:0002559 go-plus.json http://purl.obolibrary.org/obo/RO_0002559 NCBITaxon:29547 biolink:OrganismalEntity Epsilonproteobacteria go-plus.json Purple bacteria, epsilon subdivision|Campylobacterota|Proteobacteria epsilon subdivision|epsilon proteobacteria|epsilon subdivision|epsilon subgroup|Epsilonbacteraeota|e-proteobacteria http://purl.obolibrary.org/obo/NCBITaxon_29547 CHEBI:67152 biolink:ChemicalSubstance (2Z)-2-hydroxypenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67152 chebi_ph7_3 CHEBI:67153 biolink:ChemicalSubstance (+)-larreatricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_67153 chebi_ph7_3 CHEBI:67154 biolink:ChemicalSubstance (+)-3'-hydroxylarreatricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_67154 chebi_ph7_3 CHEBI:67150 biolink:ChemicalSubstance beta-D-Glc-(1->3')-1,2-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67150 chebi_ph7_3 CHEBI:67159 biolink:ChemicalSubstance fumigaclavine A go-plus.json http://purl.obolibrary.org/obo/CHEBI_67159 RO:0002551 biolink:OntologyClass A relation between a subdivision of an organism and the single subdivision of skeleton that provides structural support for that subdivision. RO:0002551 go-plus.json has sekeletal support|has supporting framework http://purl.obolibrary.org/obo/RO_0002551 CHEBI:67156 biolink:ChemicalSubstance fumigaclavine B go-plus.json http://purl.obolibrary.org/obo/CHEBI_67156 CHEBI:67158 biolink:ChemicalSubstance (R)-3-ammonio-3-phenylpropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67158 chebi_ph7_3 PR:000028205 biolink:Protein type III interferon A class 2 cytokine, IL-10 type that binds to a specific cell surface receptor complex known as the IFN type III receptor, a heterodimer consisting of IFNLR1 and IL-10R2. go-plus.json IFN type III|interferon type III|interferon lambda http://purl.obolibrary.org/obo/PR_000028205 CHEBI:82798 biolink:ChemicalSubstance cembrene C go-plus.json http://purl.obolibrary.org/obo/CHEBI_82798 chebi_ph7_3 CHEBI:82799 biolink:ChemicalSubstance (R)-nephthenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82799 chebi_ph7_3 CHEBI:67168 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67168 CHEBI:82795 biolink:ChemicalSubstance gamma-methyl L-glutamate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82795 chebi_ph7_3 PR:000018880 biolink:Protein acrosin proteolytic cleavage product An acrosin that has been processed by proteolytic cleavage. go-plus.json ACR/ClvPrd http://purl.obolibrary.org/obo/PR_000018880 CHEBI:67176 biolink:ChemicalSubstance 1-deoxy-3-dehydrosphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67176 CHEBI:67172 biolink:ChemicalSubstance (R)-3-amino-3-phenylpropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67172 CHEBI:67177 biolink:ChemicalSubstance 1-deoxymethyl-3-dehydrosphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67177 chebi_ph7_3 CHEBI:67178 biolink:ChemicalSubstance UDP-N,N'-diacetylbacillosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67178 PR:000028269 biolink:Protein thyroid stimulating hormone A protein complex that is a heterodimer of an alpha subunit (CGA) common to several glycoprotein hormones and a beta subunit (TSHB) unique to thyroid stimulating hormone. go-plus.json TSH|thyrotropin http://purl.obolibrary.org/obo/PR_000028269 CHEBI:67186 biolink:ChemicalSubstance 1-deoxymethyl-3-dehydrosphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67186 CHEBI:67187 biolink:ChemicalSubstance 1-deoxymethylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67187 CHEBI:67182 biolink:ChemicalSubstance sporulenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67182 chebi_ph7_3 CHEBI:67188 biolink:ChemicalSubstance 9-cis-beta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_67188 chebi_ph7_3 CHEBI:67189 biolink:ChemicalSubstance EC 3.4.24.3 (microbial collagenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_67189 CHEBI:67190 biolink:ChemicalSubstance carlactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_67190 chebi_ph7_3 CHEBI:67195 biolink:ChemicalSubstance gap junctional intercellular communication inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_67195 CHEBI:67196 biolink:ChemicalSubstance phytocannabinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67196 CHEBI:67197 biolink:ChemicalSubstance endocannabinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67197 CHEBI:67198 biolink:ChemicalSubstance retinoic acid receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_67198 CHEBI:67191 biolink:ChemicalSubstance (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_67191 chebi_ph7_3 CHEBI:67192 biolink:ChemicalSubstance 9-cis-10'-apo-beta-carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_67192 chebi_ph7_3 CHEBI:67193 biolink:ChemicalSubstance 4-methylheptane go-plus.json http://purl.obolibrary.org/obo/CHEBI_67193 chebi_ph7_3 CHEBI:67194 biolink:ChemicalSubstance cannabinoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67194 CHEBI:67199 biolink:ChemicalSubstance AP-1 antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_67199 RO:0002505 biolink:OntologyClass has intermediate p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c RO:0002505 go-plus.json http://purl.obolibrary.org/obo/RO_0002505 RO:0002506 biolink:OntologyClass causal relation between entities RO:0002506 go-plus.json http://purl.obolibrary.org/obo/RO_0002506 RO:0002500 biolink:OntologyClass causal agent in process A relationship between a material entity and a process where the material entity has some causal role that influences the process RO:0002500 go-plus.json http://purl.obolibrary.org/obo/RO_0002500 RO:0002501 biolink:OntologyClass causal relation between processes p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q. RO:0002501 go-plus.json http://purl.obolibrary.org/obo/RO_0002501 RO:0002502 biolink:OntologyClass depends on RO:0002502 go-plus.json http://purl.obolibrary.org/obo/RO_0002502 CHEBI:149499 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_149499 chebi_ph7_3 CHEBI:149498 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_149498 chebi_ph7_3 UBERON:0018543 biolink:AnatomicalEntity lumen of intestine The anatomical space within the intestine. go-plus.json gut lumen|intestine lumen|intestinal lumen http://purl.obolibrary.org/obo/UBERON_0018543 CHEBI:57729 biolink:ChemicalSubstance 3alpha-hydroxyglycyrrhetinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57729 chebi_ph7_3 CHEBI:57727 biolink:ChemicalSubstance N-formylmethanofuran(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57727 chebi_ph7_3 CHEBI:57728 biolink:ChemicalSubstance morphiniumone(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57728 chebi_ph7_3 CHEBI:57726 biolink:ChemicalSubstance D-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57726 chebi_ph7_3 UBERON:0018544 biolink:AnatomicalEntity trigeminal nerve muscle Muscle innervated by the trigeminal nerve (Cranial Nerve V). go-plus.json muscles innervated by the trigeminal nerve|muscle innervated by the trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0018544 CHEBI:33752 biolink:ChemicalSubstance hexonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33752 CHEBI:18119 biolink:ChemicalSubstance ethyl 3-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18119 chebi_ph7_3 CHEBI:33753 biolink:ChemicalSubstance pentonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33753 CHEBI:33754 biolink:ChemicalSubstance trionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33754 CHEBI:18117 biolink:ChemicalSubstance 3-ADP-2-phosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18117 CHEBI:18118 biolink:ChemicalSubstance L-xylono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18118 chebi_ph7_3 CHEBI:33755 biolink:ChemicalSubstance tetronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33755 CHEBI:57723 biolink:ChemicalSubstance sucrose 6(F)-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57723 chebi_ph7_3 CHEBI:18115 biolink:ChemicalSubstance 4-hydroxymandelonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_18115 chebi_ph7_3 CHEBI:57724 biolink:ChemicalSubstance dCTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57724 CHEBI:18116 biolink:ChemicalSubstance pseudouridine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18116 CHEBI:57721 biolink:ChemicalSubstance 3-amino-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57721 chebi_ph7_3 CHEBI:18113 biolink:ChemicalSubstance D-galactosyl-(1->3)-N-acetyl-beta-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18113 chebi_ph7_3 CHEBI:57722 biolink:ChemicalSubstance N(2),N(5)-dibenzoyl-L-ornithinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57722 chebi_ph7_3 CHEBI:18111 biolink:ChemicalSubstance ribosomal RNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_18111 CHEBI:57720 biolink:ChemicalSubstance alpha-D-ribose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57720 chebi_ph7_3 CHEBI:18112 biolink:ChemicalSubstance 2-aminophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18112 chebi_ph7_3 RO:0002608 biolink:OntologyClass process has causal agent Inverse of 'causal agent in process' RO:0002608 go-plus.json http://purl.obolibrary.org/obo/RO_0002608 CHEBI:18110 biolink:ChemicalSubstance 3-phosphonatooxypyruvate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18110 chebi_ph7_3 GO:0005505 biolink:MolecularActivity obsolete heavy metal binding OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. go-plus.json heavy metal binding http://purl.obolibrary.org/obo/GO_0005505 GO:0005506 biolink:MolecularActivity iron ion binding Binding to an iron (Fe) ion. go-plus.json iron binding http://purl.obolibrary.org/obo/GO_0005506 GO:0005503 biolink:MolecularActivity all-trans retinal binding Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A. go-plus.json vitamin A binding|all-trans retinaldehyde binding|trans retinal binding|xanthopsin|visual yellow binding http://purl.obolibrary.org/obo/GO_0005503 CHEBI:57718 biolink:ChemicalSubstance barbiturate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57718 GO:0005504 biolink:MolecularActivity fatty acid binding Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0005504 CHEBI:57719 biolink:ChemicalSubstance D-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57719 chebi_ph7_3 GO:0005501 biolink:MolecularActivity retinoid binding Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. Reactome:R-HSA-2454113|Reactome:R-HSA-2465938|Reactome:R-HSA-2465934|Reactome:R-HSA-2464809 go-plus.json http://purl.obolibrary.org/obo/GO_0005501 CHEBI:57716 biolink:ChemicalSubstance O-acetyl-L-homoserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57716 chebi_ph7_3 GO:0005502 biolink:MolecularActivity 11-cis retinal binding Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A. go-plus.json 11-cis-retinal binding|vitamin A binding|11-cis retinaldehyde binding http://purl.obolibrary.org/obo/GO_0005502 CHEBI:57714 biolink:ChemicalSubstance 2-ureidoglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57714 chebi_ph7_3 GO:0005500 biolink:MolecularActivity juvenile hormone binding Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0005500 CHEBI:57715 biolink:ChemicalSubstance UDP-N-acetyl-D-mannosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57715 chebi_ph7_3 CHEBI:33767 biolink:ChemicalSubstance cobalt group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33767 CHEBI:33769 biolink:ChemicalSubstance fuconates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33769 CHEBI:33760 biolink:ChemicalSubstance hexonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33760 CHEBI:33761 biolink:ChemicalSubstance pentonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33761 CHEBI:33762 biolink:ChemicalSubstance tetronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33762 CHEBI:33763 biolink:ChemicalSubstance trionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33763 CHEBI:33764 biolink:ChemicalSubstance arabinonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33764 CHEBI:18106 biolink:ChemicalSubstance deacetylipecoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_18106 CHEBI:18107 biolink:ChemicalSubstance xanthosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18107 chebi_ph7_3 CHEBI:57712 biolink:ChemicalSubstance 2-hydroxy-3-oxoadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57712 chebi_ph7_3 CHEBI:18104 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-fuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18104 CHEBI:57713 biolink:ChemicalSubstance 3-(2-carboxylatoethenyl)-cis,cis-muconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57713 chebi_ph7_3 CHEBI:57710 biolink:ChemicalSubstance 5,12-dihydroxanthommatin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57710 chebi_ph7_3 CHEBI:18102 biolink:ChemicalSubstance O-octanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18102 chebi_ph7_3 CHEBI:18103 biolink:ChemicalSubstance L-tyrosine methyl ester 4-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18103 CHEBI:57711 biolink:ChemicalSubstance all-trans-octaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57711 chebi_ph7_3 GO:0005509 biolink:MolecularActivity calcium ion binding Binding to a calcium ion (Ca2+). go-plus.json calcium ion storage activity http://purl.obolibrary.org/obo/GO_0005509 CHEBI:18100 biolink:ChemicalSubstance multi-methyl-branched fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_18100 CHEBI:18101 biolink:ChemicalSubstance 4-hydroxyphenylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18101 GO:0005507 biolink:MolecularActivity copper ion binding Binding to a copper (Cu) ion. go-plus.json copper/cadmium binding|copper binding http://purl.obolibrary.org/obo/GO_0005507 GO:0005508 biolink:MolecularActivity obsolete copper/cadmium binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json copper/cadmium binding http://purl.obolibrary.org/obo/GO_0005508 CHEBI:18140 biolink:ChemicalSubstance hydrogen halide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18140 chebi_ph7_3 CHEBI:57709 biolink:ChemicalSubstance 2-amino-3-oxo-4-(phosphonatooxy)butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57709 CHEBI:57707 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)glycerol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57707 chebi_ph7_3 CHEBI:82707 biolink:ChemicalSubstance ergothioneine thione form go-plus.json http://purl.obolibrary.org/obo/CHEBI_82707 chebi_ph7_3 CHEBI:57708 biolink:ChemicalSubstance benzoylagmatinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57708 chebi_ph7_3 CHEBI:57705 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-glucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57705 chebi_ph7_3 CHEBI:82705 biolink:ChemicalSubstance hercynylselenocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_82705 chebi_ph7_3 CHEBI:82706 biolink:ChemicalSubstance hercynylcysteine sulfoxide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_82706 chebi_ph7_3 CHEBI:57706 biolink:ChemicalSubstance 4-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57706 chebi_ph7_3 CHEBI:57703 biolink:ChemicalSubstance 2-nitrophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57703 chebi_ph7_3 CHEBI:82703 biolink:ChemicalSubstance N(alpha)-(L-gamma-glutamyl)-hercynyl-L-cysteine sulfoxide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_82703 chebi_ph7_3 CHEBI:57704 biolink:ChemicalSubstance cationic chitosan go-plus.json http://purl.obolibrary.org/obo/CHEBI_57704 chebi_ph7_3 CHEBI:33737 biolink:ChemicalSubstance di-mu-sulfido-diiron(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33737 chebi_ph7_3 CHEBI:33738 biolink:ChemicalSubstance di-mu-sulfido-diiron(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33738 chebi_ph7_3 CHEBI:33731 biolink:ChemicalSubstance cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_33731 CHEBI:18139 biolink:ChemicalSubstance trimethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18139 CHEBI:33733 biolink:ChemicalSubstance heteronuclear cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_33733 CHEBI:57701 biolink:ChemicalSubstance 5-O-(1-carboxylatovinyl)-3-phosphonatoshikimate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57701 chebi_ph7_3 CHEBI:18137 biolink:ChemicalSubstance heparan sulfate alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18137 CHEBI:57702 biolink:ChemicalSubstance N-acetyl-L-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57702 chebi_ph7_3 CHEBI:18138 biolink:ChemicalSubstance biuret go-plus.json http://purl.obolibrary.org/obo/CHEBI_18138 chebi_ph7_3 CHEBI:18135 biolink:ChemicalSubstance catechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18135 chebi_ph7_3 CHEBI:18136 biolink:ChemicalSubstance 3-(2,3-dihydroxyphenyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18136 CHEBI:57700 biolink:ChemicalSubstance 2-methyl-3-oxopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57700 chebi_ph7_3 CHEBI:18133 biolink:ChemicalSubstance hexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18133 CHEBI:18134 biolink:ChemicalSubstance 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18134 CHEBI:18131 biolink:ChemicalSubstance licodione go-plus.json http://purl.obolibrary.org/obo/CHEBI_18131 CHEBI:18132 biolink:ChemicalSubstance phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18132 CHEBI:18130 biolink:ChemicalSubstance (-)-5-oxo-1,2-campholide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18130 chebi_ph7_3 CHEBI:33745 biolink:ChemicalSubstance copper group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33745 CHEBI:33746 biolink:ChemicalSubstance vanadium group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33746 CHEBI:82710 biolink:ChemicalSubstance S-alkyl-L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_82710 chebi_ph7_3 CHEBI:33747 biolink:ChemicalSubstance nickel group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33747 CHEBI:33748 biolink:ChemicalSubstance nickel molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33748 CHEBI:82711 biolink:ChemicalSubstance aryl thiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82711 chebi_ph7_3 CHEBI:33749 biolink:ChemicalSubstance platinum molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33749 CHEBI:33741 biolink:ChemicalSubstance chromium group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33741 CHEBI:33742 biolink:ChemicalSubstance tungsten molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33742 UBERON:0018508 biolink:AnatomicalEntity foramen of nasal bone A vascular foramen opening on the outer surface of a nasal bone. go-plus.json foramen of nasal bone|nasal foramina|foramina nasalia|nasal foramen http://purl.obolibrary.org/obo/UBERON_0018508 CHEBI:33743 biolink:ChemicalSubstance manganese group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33743 CHEBI:18128 biolink:ChemicalSubstance luteolin 7-O-beta-D-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18128 CHEBI:18129 biolink:ChemicalSubstance (S)-2-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18129 CHEBI:33744 biolink:ChemicalSubstance iron group molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33744 CHEBI:18126 biolink:ChemicalSubstance S-acylglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_18126 CHEBI:18127 biolink:ChemicalSubstance cadaverine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18127 CHEBI:18124 biolink:ChemicalSubstance phosphonoacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18124 CHEBI:18125 biolink:ChemicalSubstance trans-2-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18125 CHEBI:18123 biolink:ChemicalSubstance N-methylnicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18123 chebi_ph7_3 CHEBI:18120 biolink:ChemicalSubstance 5-aminopentanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18120 CHEBI:82728 biolink:ChemicalSubstance S-(5-histidyl)cysteine sulfoxide dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_82728 chebi_ph7_3 CHEBI:33712 biolink:ChemicalSubstance N-terminal amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33712 CHEBI:33713 biolink:ChemicalSubstance C-terminal alpha-amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33713 CHEBI:33715 biolink:ChemicalSubstance N-terminal alpha-amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33715 CHEBI:33716 biolink:ChemicalSubstance N-terminal proteinogenic amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33716 CHEBI:33717 biolink:ChemicalSubstance C-terminal proteinogenic amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33717 CHEBI:33719 biolink:ChemicalSubstance alpha-amino-acid cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33719 CHEBI:33710 biolink:ChemicalSubstance alpha-amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33710 CHEBI:33711 biolink:ChemicalSubstance C-terminal amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33711 CHEBI:82736 biolink:ChemicalSubstance N-acylphytosphingosine-1-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82736 CHEBI:82737 biolink:ChemicalSubstance N-hexadecanoylphytosphingosine-1-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82737 CHEBI:82734 biolink:ChemicalSubstance N-acylsphinganine-1-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82734 CHEBI:33723 biolink:ChemicalSubstance tetra-mu3-sulfido-tetrairon(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33723 chebi_ph7_3 CHEBI:67104 biolink:ChemicalSubstance 4-nitro-6-oxohepta-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67104 CHEBI:82735 biolink:ChemicalSubstance O-[S-(6-methoxycarbonylhexanoyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82735 chebi_ph7_3 CHEBI:82732 biolink:ChemicalSubstance N-hexadecanoylsphinganine-1-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_82732 CHEBI:67106 biolink:ChemicalSubstance 1-deoxysphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_67106 CHEBI:33726 biolink:ChemicalSubstance proteinogenic amino-acid residue anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33726 CHEBI:33727 biolink:ChemicalSubstance proteinogenic amino-acid residue cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33727 CHEBI:82730 biolink:ChemicalSubstance (7Z)-hexadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82730 chebi_ph7_3 CHEBI:33728 biolink:ChemicalSubstance proteinogenic amino-acid residue radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_33728 CHEBI:33729 biolink:ChemicalSubstance tetritol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33729 CHEBI:67103 biolink:ChemicalSubstance (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_67103 CHEBI:67108 biolink:ChemicalSubstance 1-deoxymethylsphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67108 chebi_ph7_3 CHEBI:67109 biolink:ChemicalSubstance 1-deoxysphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_67109 chebi_ph7_3 CHEBI:33720 biolink:ChemicalSubstance carbohydrate acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33720 CHEBI:33721 biolink:ChemicalSubstance carbohydrate acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33721 CHEBI:33722 biolink:ChemicalSubstance tetra-mu3-sulfido-tetrairon(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33722 chebi_ph7_3 CHEBI:82747 biolink:ChemicalSubstance (9Z,12Z)-heptadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82747 CHEBI:82748 biolink:ChemicalSubstance cytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82748 chebi_ph7_3 CHEBI:82745 biolink:ChemicalSubstance (9Z,12Z)-tetradecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82745 CHEBI:67115 biolink:ChemicalSubstance ecgonone methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_67115 CHEBI:82746 biolink:ChemicalSubstance (9Z,12Z)-pentadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82746 CHEBI:82743 biolink:ChemicalSubstance 5-methylaminomethyl-2-selenouridine 5'-monophosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_82743 chebi_ph7_3 CHEBI:67117 biolink:ChemicalSubstance trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_67117 CHEBI:82744 biolink:ChemicalSubstance aliphatic aldoxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_82744 chebi_ph7_3 CHEBI:67118 biolink:ChemicalSubstance UDP-alpha-D-galactofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_67118 CHEBI:82741 biolink:ChemicalSubstance (5Z,11Z,14Z,17Z)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82741 CHEBI:82742 biolink:ChemicalSubstance (8Z,11Z)-icosadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82742 CHEBI:67114 biolink:ChemicalSubstance ryanodine receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_67114 CHEBI:82740 biolink:ChemicalSubstance (5Z,11Z,14Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_82740 CHEBI:67119 biolink:ChemicalSubstance UDP-alpha-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_67119 NCBITaxon:6340 biolink:OrganismalEntity Annelida go-plus.json segmented worms|annelid worms http://purl.obolibrary.org/obo/NCBITaxon_6340 CHEBI:33709 biolink:ChemicalSubstance amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33709 CHEBI:82759 biolink:ChemicalSubstance (S)-3-acetyloctanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_82759 chebi_ph7_3 CHEBI:33702 biolink:ChemicalSubstance polyatomic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33702 CHEBI:82757 biolink:ChemicalSubstance 2-hydroxy-5-methyl-1-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82757 chebi_ph7_3 CHEBI:33703 biolink:ChemicalSubstance amino-acid cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_33703 NCBITaxon:1535325 biolink:OrganismalEntity Candida/Lodderomyces clade go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1535325 CHEBI:33704 biolink:ChemicalSubstance alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33704 CHEBI:67122 biolink:ChemicalSubstance alpha-D-abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67122 CHEBI:82753 biolink:ChemicalSubstance 1-oleoyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_82753 CHEBI:33706 biolink:ChemicalSubstance beta-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33706 CHEBI:33707 biolink:ChemicalSubstance gamma-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33707 CHEBI:82750 biolink:ChemicalSubstance cholesteryl stearate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82750 chebi_ph7_3 CHEBI:67124 biolink:ChemicalSubstance alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67124 CHEBI:82751 biolink:ChemicalSubstance cholesteryl arachidonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_82751 chebi_ph7_3 CHEBI:33708 biolink:ChemicalSubstance amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33708 NCBITaxon:1535326 biolink:OrganismalEntity Candida go-plus.json Candida http://purl.obolibrary.org/obo/NCBITaxon_1535326 CHEBI:33700 biolink:ChemicalSubstance proteinogenic amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33700 NCBITaxon:78536 biolink:OrganismalEntity Euphyllophyta go-plus.json euphyllophytes http://purl.obolibrary.org/obo/NCBITaxon_78536 GO:0030538 biolink:BiologicalProcess embryonic genitalia morphogenesis The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized. go-plus.json embryonic genital morphogenesis http://purl.obolibrary.org/obo/GO_0030538 GO:0030539 biolink:BiologicalProcess male genitalia development The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. go-plus.json male genital development http://purl.obolibrary.org/obo/GO_0030539 GO:0030536 biolink:BiologicalProcess larval feeding behavior Feeding behavior in a larval (immature) organism. go-plus.json larval feeding behaviour http://purl.obolibrary.org/obo/GO_0030536 GO:0030537 biolink:BiologicalProcess larval behavior Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics. go-plus.json larval behaviour http://purl.obolibrary.org/obo/GO_0030537 GO:0030534 biolink:BiologicalProcess adult behavior Behavior in a fully developed and mature organism. go-plus.json adult behavioural response to stimulus|adult behavioral response to stimulus|adult behaviour http://purl.obolibrary.org/obo/GO_0030534 GO:0005578 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005578 GO:0005579 biolink:CellularComponent membrane attack complex A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. Wikipedia:Complement_membrane_attack_complex go-plus.json TCC|membrane attack complex protein beta2 chain|MAC|membrane attack complex protein alphaM chain|terminal complement complex http://purl.obolibrary.org/obo/GO_0005579 GO:0030535 biolink:BiologicalProcess obsolete adult feeding behavior (sensu Insecta) OBSOLETE. Feeding behavior in a fully developed and mature organism, as described in insects. go-plus.json adult feeding behavior (sensu Insecta) http://purl.obolibrary.org/obo/GO_0030535 GO:0005576 biolink:CellularComponent extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. Wikipedia:Extracellular go-plus.json extracellular http://purl.obolibrary.org/obo/GO_0005576 goslim_mouse|goslim_yeast|goslim_candida|goslim_agr|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_flybase_ribbon|goslim_chembl GO:0030532 biolink:CellularComponent small nuclear ribonucleoprotein complex A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs. Wikipedia:SnRNP go-plus.json snRNP|small nuclear ribonucleoprotein http://purl.obolibrary.org/obo/GO_0030532 goslim_pir GO:0005577 biolink:CellularComponent fibrinogen complex A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. go-plus.json fibrinogen gamma chain|fibrinogen alpha chain|fibrinogen beta chain|fibrinogen http://purl.obolibrary.org/obo/GO_0005577 GO:0030533 biolink:MolecularActivity triplet codon-amino acid adaptor activity The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis. go-plus.json tRNA|transfer RNA http://purl.obolibrary.org/obo/GO_0030533 goslim_chembl|goslim_yeast|goslim_candida|goslim_aspergillus|goslim_generic GO:0005574 biolink:CellularComponent obsolete DNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA http://purl.obolibrary.org/obo/GO_0005574 GO:0005575 biolink:CellularComponent cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). NIF_Subcellular:sao1337158144 go-plus.json cellular component|subcellular entity|cell or subcellular entity http://purl.obolibrary.org/obo/GO_0005575 goslim_yeast|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl GO:0005572 biolink:CellularComponent obsolete RNA polymerase II transcribed untranslated RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json RNA polymerase II transcribed untranslated RNA http://purl.obolibrary.org/obo/GO_0005572 GO:0005573 biolink:CellularComponent obsolete telomerase RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json telomerase RNA http://purl.obolibrary.org/obo/GO_0005573 GO:0005570 biolink:MolecularActivity obsolete small nuclear RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json small nuclear RNA http://purl.obolibrary.org/obo/GO_0005570 GO:0005571 biolink:CellularComponent obsolete untranslated RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json untranslated RNA http://purl.obolibrary.org/obo/GO_0005571 GO:0030530 biolink:CellularComponent obsolete heterogeneous nuclear ribonucleoprotein complex OBSOLETE. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. Wikipedia:Heterogeneous_ribonucleoprotein_particle go-plus.json heterogeneous nuclear ribonucleoprotein|hnRNP|heterogeneous nuclear ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0030530 GO:0030531 biolink:CellularComponent obsolete small cytoplasmic ribonucleoprotein complex OBSOLETE. A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm. go-plus.json small cytoplasmic ribonucleoprotein|small cytoplasmic ribonucleoprotein complex|scRNP http://purl.obolibrary.org/obo/GO_0030531 CHEBI:18199 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18199 CHEBI:18197 biolink:ChemicalSubstance ditrans,polycis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18197 CHEBI:18198 biolink:ChemicalSubstance 4-amino-4-deoxychorismic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18198 CHEBI:18195 biolink:ChemicalSubstance alpha,alpha'-trehalose 6,6'-bismycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18195 chebi_ph7_3 GO:0030527 biolink:MolecularActivity structural constituent of chromatin The action of a molecule that contributes to the structural integrity of chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0030527 GO:0030528 biolink:MolecularActivity obsolete transcription regulator activity OBSOLETE. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. go-plus.json transcriptional regulator activity|transcription regulator activity http://purl.obolibrary.org/obo/GO_0030528 CHEBI:18193 biolink:ChemicalSubstance 10-deacetylbaccatin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_18193 chebi_ph7_3 GO:0030525 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030525 GO:0030526 biolink:CellularComponent granulocyte macrophage colony-stimulating factor receptor complex The heterodimeric receptor for granulocyte macrophage colony-stimulating factor. go-plus.json GM-CSF receptor complex|granulocyte macrophage colony stimulating factor receptor complex http://purl.obolibrary.org/obo/GO_0030526 GO:0030523 biolink:MolecularActivity dihydrolipoamide S-acyltransferase activity Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide. EC:2.3.1.12 go-plus.json http://purl.obolibrary.org/obo/GO_0030523 GO:0005589 biolink:CellularComponent collagen type VI trimer A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005589 GO:0030524 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030524 GO:0005587 biolink:CellularComponent collagen type IV trimer A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. Wikipedia:Collagen_type_IV go-plus.json http://purl.obolibrary.org/obo/GO_0005587 GO:0030521 biolink:BiologicalProcess androgen receptor signaling pathway Any series of molecular signals generated as a consequence of an androgen binding to its receptor. go-plus.json androgen receptor signalling pathway http://purl.obolibrary.org/obo/GO_0030521 GO:0030522 biolink:BiologicalProcess intracellular receptor signaling pathway Any series of molecular signals initiated by a ligand binding to an receptor located within a cell. go-plus.json intracellular receptor-mediated signaling pathway|intracellular receptor-mediated signalling pathway|intracellular receptor mediated signaling pathway http://purl.obolibrary.org/obo/GO_0030522 GO:0005588 biolink:CellularComponent collagen type V trimer A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005588 GO:0005585 biolink:CellularComponent collagen type II trimer A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. Wikipedia:Collagen_type_II go-plus.json http://purl.obolibrary.org/obo/GO_0005585 GO:0005586 biolink:CellularComponent collagen type III trimer A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005586 GO:0005583 biolink:CellularComponent fibrillar collagen trimer Any triple helical collagen trimer that forms fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005583 GO:0005584 biolink:CellularComponent collagen type I trimer A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils. Wikipedia:Collagen_type_I go-plus.json http://purl.obolibrary.org/obo/GO_0005584 GO:0005581 biolink:CellularComponent collagen trimer A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen go-plus.json http://purl.obolibrary.org/obo/GO_0005581 GO:0005582 biolink:CellularComponent collagen type XV trimer A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0005582 GO:0030529 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030529 OBO:GOREL_0001006 biolink:OntologyClass acts_on_population_of GOREL:0001006 go-plus.json alters levels of http://purl.obolibrary.org/obo/GOREL_0001006 GO:0005580 biolink:CellularComponent obsolete membrane attack complex protein alphaM chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json membrane attack complex protein alphaM chain http://purl.obolibrary.org/obo/GO_0005580 CHEBI:57792 biolink:ChemicalSubstance 1-deoxy-D-xylulose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57792 chebi_ph7_3 CHEBI:57790 biolink:ChemicalSubstance benzyl cetraxate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57790 chebi_ph7_3 CHEBI:57791 biolink:ChemicalSubstance meso-2,6-diaminopimelic acid dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57791 chebi_ph7_3 GO:0030520 biolink:BiologicalProcess intracellular estrogen receptor signaling pathway Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription). go-plus.json estrogen receptor signalling pathway|estrogen receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030520 CHEBI:57798 biolink:ChemicalSubstance 1D-myo-inositol 1,2,4,5,6-pentakisphosphate(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57798 chebi_ph7_3 CHEBI:57799 biolink:ChemicalSubstance 4',5-dihydroxy-3'-methoxyflavon-7-olate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57799 chebi_ph7_3 CHEBI:18188 biolink:ChemicalSubstance (S)-3-aminoisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18188 CHEBI:57797 biolink:ChemicalSubstance dihydrostreptomycin 6-phosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57797 chebi_ph7_3 CHEBI:18186 biolink:ChemicalSubstance tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18186 CHEBI:57794 biolink:ChemicalSubstance dGTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57794 CHEBI:57795 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57795 chebi_ph7_3 CHEBI:18187 biolink:ChemicalSubstance (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18187 GO:0030516 biolink:BiologicalProcess regulation of axon extension Any process that modulates the rate, direction or extent of axon extension. go-plus.json http://purl.obolibrary.org/obo/GO_0030516 GO:0030517 biolink:BiologicalProcess negative regulation of axon extension Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth. go-plus.json down-regulation of axon extension|downregulation of axon extension|down regulation of axon extension|inhibition of axon extension http://purl.obolibrary.org/obo/GO_0030517 GO:0030514 biolink:BiologicalProcess negative regulation of BMP signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway. go-plus.json negative regulation of BMP signalling pathway|negative regulation of bone morphogenetic protein signaling pathway|down regulation of BMP signaling pathway|downregulation of BMP signaling pathway|negative regulation of BMP receptor signaling pathway|negative regulation of decapentaplegic receptor signaling pathway|negative regulation of bone morphogenetic protein signalling pathway|negative regulation of decapentaplegic receptor signalling pathway|down-regulation of BMP signaling pathway|negative regulation of decapentaplegic signaling pathway|inhibition of BMP signaling pathway http://purl.obolibrary.org/obo/GO_0030514 GO:0005558 biolink:MolecularActivity obsolete minor histocompatibility antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json minor histocompatibility antigen http://purl.obolibrary.org/obo/GO_0005558 CHEBI:149502 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_149502 chebi_ph7_3 GO:0005559 biolink:CellularComponent obsolete ribozyme OBSOLETE. (Was not defined before being made obsolete). go-plus.json ribozyme http://purl.obolibrary.org/obo/GO_0005559 GO:0030515 biolink:MolecularActivity snoRNA binding Binding to a small nucleolar RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0030515 GO:0030512 biolink:BiologicalProcess negative regulation of transforming growth factor beta receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway. go-plus.json negative regulation of transforming growth factor beta receptor signalling pathway|down regulation of transforming growth factor beta receptor signaling pathway|inhibition of transforming growth factor beta receptor signaling pathway|negative regulation of TGFbeta receptor signaling pathway|negative regulation of TGF-beta receptor signaling pathway|down-regulation of transforming growth factor beta receptor signaling pathway|downregulation of transforming growth factor beta receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030512 GO:0030513 biolink:BiologicalProcess positive regulation of BMP signaling pathway Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity. go-plus.json positive regulation of BMP signalling pathway|upregulation of BMP signaling pathway|positive regulation of bone morphogenetic protein signaling pathway|positive regulation of bone morphogenetic protein signalling pathway|positive regulation of decapentaplegic receptor signalling pathway|up regulation of BMP signaling pathway|positive regulation of BMP receptor signaling pathway|activation of BMP signaling pathway|positive regulation of decapentaplegic receptor signaling pathway|positive regulation of decapentaplegic signaling pathway|stimulation of BMP signaling pathway|up-regulation of BMP signaling pathway http://purl.obolibrary.org/obo/GO_0030513 GO:0005557 biolink:MolecularActivity obsolete lymphocyte antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json lymphocyte antigen http://purl.obolibrary.org/obo/GO_0005557 GO:0030510 biolink:BiologicalProcess regulation of BMP signaling pathway Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway. go-plus.json regulation of bone morphogenetic protein signalling pathway|regulation of decapentaplegic receptor signalling pathway|regulation of decapentaplegic signaling pathway|regulation of BMP signalling pathway|regulation of bone morphogenetic protein signaling pathway|regulation of BMP receptor signaling pathway|regulation of decapentaplegic receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030510 GO:0005554 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005554 GO:0030511 biolink:BiologicalProcess positive regulation of transforming growth factor beta receptor signaling pathway Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity. go-plus.json positive regulation of TGF-beta receptor signaling pathway|upregulation of transforming growth factor beta receptor signaling pathway|positive regulation of TGFbeta receptor signaling pathway|stimulation of transforming growth factor beta receptor signaling pathway|up-regulation of transforming growth factor beta receptor signaling pathway|activation of transforming growth factor beta receptor signaling pathway|up regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signalling pathway http://purl.obolibrary.org/obo/GO_0030511 GO:0005555 biolink:MolecularActivity obsolete blood group antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json blood group antigen http://purl.obolibrary.org/obo/GO_0005555 GO:0005552 biolink:MolecularActivity obsolete polyubiquitin OBSOLETE. (Was not defined before being made obsolete). go-plus.json polyubiquitin http://purl.obolibrary.org/obo/GO_0005552 GO:0005553 biolink:MolecularActivity obsolete ubiquitin-ribosomal protein fusion protein OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein. go-plus.json ubiquitin-ribosomal protein fusion protein http://purl.obolibrary.org/obo/GO_0005553 GO:0005550 biolink:MolecularActivity pheromone binding Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. go-plus.json http://purl.obolibrary.org/obo/GO_0005550 GO:0005551 biolink:MolecularActivity obsolete ubiquitin OBSOLETE. (Was not defined before being made obsolete). go-plus.json http://purl.obolibrary.org/obo/GO_0005551 CHEBI:149500 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_149500 chebi_ph7_3 GO:0030518 biolink:BiologicalProcess intracellular steroid hormone receptor signaling pathway A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands. go-plus.json steroid hormone receptor signalling pathway|steroid hormone receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030518 GO:0030519 biolink:MolecularActivity snoRNP binding Binding to a small nucleolar ribonucleoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0030519 CHEBI:57781 biolink:ChemicalSubstance N-methylethanolaminium phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57781 chebi_ph7_3 CHEBI:57782 biolink:ChemicalSubstance cortisol 21-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57782 chebi_ph7_3 CHEBI:149509 biolink:ChemicalSubstance candesartan(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_149509 chebi_ph7_3 CHEBI:57787 biolink:ChemicalSubstance streptomycin 6-phosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57787 chebi_ph7_3 CHEBI:57788 biolink:ChemicalSubstance isonocardicin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57788 CHEBI:57783 biolink:ChemicalSubstance NADPH(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57783 chebi_ph7_3 CHEBI:57784 biolink:ChemicalSubstance 2-[3-carboxylato-3-(methylammonio)propyl]-L-histidine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57784 chebi_ph7_3 GO:0030505 biolink:BiologicalProcess inorganic diphosphate transport The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json inorganic pyrophosphate transport http://purl.obolibrary.org/obo/GO_0030505 GO:0030506 biolink:MolecularActivity ankyrin binding Binding to ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0030506 GO:0030503 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0030503 GO:0005569 biolink:MolecularActivity obsolete small nucleolar RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json small nucleolar RNA http://purl.obolibrary.org/obo/GO_0005569 GO:0030504 biolink:MolecularActivity inorganic diphosphate transmembrane transporter activity Enables the transfer of inorganic diphosphate across a membrane. Reactome:R-HSA-5226964 go-plus.json inorganic pyrophosphate transporter activity http://purl.obolibrary.org/obo/GO_0030504 GO:0030501 biolink:BiologicalProcess positive regulation of bone mineralization Any process that activates or increases the frequency, rate or extent of bone mineralization. go-plus.json up-regulation of bone mineralization|upregulation of bone mineralization|up regulation of bone mineralization|activation of bone mineralization|stimulation of bone mineralization http://purl.obolibrary.org/obo/GO_0030501 GO:0005567 biolink:CellularComponent obsolete cytosolic ribosomal RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytosolic ribosomal RNA http://purl.obolibrary.org/obo/GO_0005567 GO:0030502 biolink:BiologicalProcess negative regulation of bone mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. go-plus.json inhibition of bone mineralization|down regulation of bone mineralization|downregulation of bone mineralization|down-regulation of bone mineralization http://purl.obolibrary.org/obo/GO_0030502 GO:0005568 biolink:CellularComponent obsolete mitochondrial rRNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json mitochondrial rRNA http://purl.obolibrary.org/obo/GO_0005568 GO:0005565 biolink:CellularComponent obsolete mitochondrial tRNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json mitochondrial tRNA http://purl.obolibrary.org/obo/GO_0005565 GO:0005566 biolink:MolecularActivity obsolete ribosomal RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json ribosomal RNA http://purl.obolibrary.org/obo/GO_0005566 GO:0030500 biolink:BiologicalProcess regulation of bone mineralization Any process that modulates the frequency, rate or extent of bone mineralization. go-plus.json http://purl.obolibrary.org/obo/GO_0030500 GO:0005563 biolink:MolecularActivity obsolete transfer RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json transfer RNA http://purl.obolibrary.org/obo/GO_0005563 GO:0005564 biolink:CellularComponent obsolete cytosolic tRNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytosolic tRNA http://purl.obolibrary.org/obo/GO_0005564 GO:0005561 biolink:CellularComponent obsolete nucleic acid OBSOLETE. (Was not defined before being made obsolete). go-plus.json nucleic acid http://purl.obolibrary.org/obo/GO_0005561 GO:0005562 biolink:CellularComponent obsolete RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json RNA http://purl.obolibrary.org/obo/GO_0005562 GO:0030509 biolink:BiologicalProcess BMP signaling pathway A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json dpp receptor signalling pathway|decapentaplegic receptor signalling pathway|decapentaplegic receptor signaling pathway|bone morphogenetic protein signalling pathway|decapentaplegic signaling pathway|BMP signalling pathway|dpp receptor signaling pathway|bone morphogenetic protein signaling pathway|dpp signaling pathway|BMP receptor signaling pathway http://purl.obolibrary.org/obo/GO_0030509 GO:0030507 biolink:MolecularActivity spectrin binding Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. go-plus.json http://purl.obolibrary.org/obo/GO_0030507 GO:0030508 biolink:MolecularActivity obsolete thiol-disulfide exchange intermediate activity OBSOLETE. Functions as an exchange intermediate in thiol-disulfide exchange reactions. go-plus.json thiol-disulphide exchange intermediate activity|thiol-disulfide exchange intermediate activity|thioredoxin|glutaredoxin http://purl.obolibrary.org/obo/GO_0030508 CHEBI:57770 biolink:ChemicalSubstance trans-caffeate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57770 chebi_ph7_3 CHEBI:57771 biolink:ChemicalSubstance UDP-N-acetyl-3-O-(1-carboxylatovinyl)-D-glucosamine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57771 chebi_ph7_3 CHEBI:57778 biolink:ChemicalSubstance triacetate lactone oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57778 CHEBI:57779 biolink:ChemicalSubstance tauropinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57779 chebi_ph7_3 CHEBI:57776 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57776 chebi_ph7_3 CHEBI:57777 biolink:ChemicalSubstance 1,4,5,6-tetrahydro-6-oxonicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57777 chebi_ph7_3 CHEBI:57774 biolink:ChemicalSubstance 2-acetyllactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57774 chebi_ph7_3 CHEBI:57775 biolink:ChemicalSubstance stipitaton-4-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57775 chebi_ph7_3 CHEBI:57772 biolink:ChemicalSubstance N-acetyl-L-histidinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57772 chebi_ph7_3 CHEBI:57773 biolink:ChemicalSubstance N-(carboxylatomethyl)-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_57773 chebi_ph7_3 GO:0005539 biolink:MolecularActivity glycosaminoglycan binding Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues. go-plus.json http://purl.obolibrary.org/obo/GO_0005539 goslim_chembl CHEBI:18163 biolink:ChemicalSubstance alpha-NeuNAc-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-NeuNAc-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_18163 GO:0005536 biolink:MolecularActivity glucose binding Binding to D- or L-enantiomers of glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0005536 GO:0005537 biolink:MolecularActivity mannose binding Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans. Reactome:R-HSA-947991 go-plus.json mannose binding lectin http://purl.obolibrary.org/obo/GO_0005537 goslim_chembl GO:0005534 biolink:MolecularActivity galactose binding Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides. go-plus.json galactose binding lectin http://purl.obolibrary.org/obo/GO_0005534 GO:0005532 biolink:MolecularActivity obsolete mannose binding lectin OBSOLETE. (Was not defined before being made obsolete). go-plus.json mannose receptor|mannose binding lectin http://purl.obolibrary.org/obo/GO_0005532 CHEBI:57769 biolink:ChemicalSubstance precorrin-4(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57769 chebi_ph7_3 GO:0005533 biolink:MolecularActivity obsolete N-acetylgalactosamine lectin OBSOLETE. (Was not defined before being made obsolete). go-plus.json N-acetylgalactosamine lectin http://purl.obolibrary.org/obo/GO_0005533 GO:0005530 biolink:MolecularActivity obsolete lectin OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell. go-plus.json lectin http://purl.obolibrary.org/obo/GO_0005530 GO:0005531 biolink:MolecularActivity obsolete galactose binding lectin OBSOLETE. (Was not defined before being made obsolete). go-plus.json galactose binding lectin http://purl.obolibrary.org/obo/GO_0005531 CHEBI:43120 biolink:ChemicalSubstance (6R)-L-erythro-6,7-dihydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_43120 chebi_ph7_3 CHEBI:33792 biolink:ChemicalSubstance canonical ribonucleoside residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33792 CHEBI:33793 biolink:ChemicalSubstance canonical deoxyribonucleoside residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33793 CHEBI:57760 biolink:ChemicalSubstance 3-oxoglycyrrhetinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57760 chebi_ph7_3 CHEBI:33794 biolink:ChemicalSubstance tRNA(fMet) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33794 CHEBI:33797 biolink:ChemicalSubstance glucaric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33797 CHEBI:33798 biolink:ChemicalSubstance tetraric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33798 CHEBI:43129 biolink:ChemicalSubstance (+)-6a-hydroxymaackiain go-plus.json http://purl.obolibrary.org/obo/CHEBI_43129 chebi_ph7_3 CHEBI:57767 biolink:ChemicalSubstance mono(glucosyluronic acid)bilirubin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57767 chebi_ph7_3 CHEBI:18159 biolink:ChemicalSubstance ribose 5-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18159 CHEBI:57768 biolink:ChemicalSubstance 4-coumaroylshikimate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57768 chebi_ph7_3 CHEBI:18157 biolink:ChemicalSubstance aerobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18157 CHEBI:57766 biolink:ChemicalSubstance 3-(imidazol-4-yl)-2-oxopropyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57766 chebi_ph7_3 CHEBI:18155 biolink:ChemicalSubstance (S)-1,2-didecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18155 chebi_ph7_3 CHEBI:57763 biolink:ChemicalSubstance limonoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57763 chebi_ph7_3 CHEBI:57764 biolink:ChemicalSubstance 1-deoxy-D-altro-heptulose 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57764 chebi_ph7_3 CHEBI:18153 biolink:ChemicalSubstance ethene go-plus.json http://purl.obolibrary.org/obo/CHEBI_18153 chebi_ph7_3 CHEBI:57761 biolink:ChemicalSubstance pyridoxaminium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57761 chebi_ph7_3 CHEBI:18154 biolink:ChemicalSubstance polysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18154 CHEBI:57762 biolink:ChemicalSubstance L-valine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57762 chebi_ph7_3 CHEBI:33791 biolink:ChemicalSubstance canonical nucleoside residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_33791 GO:0005549 biolink:MolecularActivity odorant binding Binding to an odorant, any substance capable of stimulating the sense of smell. go-plus.json http://purl.obolibrary.org/obo/GO_0005549 goslim_pir CHEBI:18151 biolink:ChemicalSubstance menaquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18151 chebi_ph7_3 CHEBI:18152 biolink:ChemicalSubstance myricetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18152 GO:0005547 biolink:MolecularActivity phosphatidylinositol-3,4,5-trisphosphate binding Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. go-plus.json PIP3 binding http://purl.obolibrary.org/obo/GO_0005547 GO:0005548 biolink:MolecularActivity phospholipid transporter activity Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester. Reactome:R-HSA-5678706|Reactome:R-HSA-216757|Reactome:R-HSA-5678749|Reactome:R-HSA-8857662|Reactome:R-HSA-8865637|Reactome:R-HSA-382553|Reactome:R-HSA-8867876 go-plus.json http://purl.obolibrary.org/obo/GO_0005548 CHEBI:18150 biolink:ChemicalSubstance 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18150 GO:0005545 biolink:MolecularActivity 1-phosphatidylinositol binding Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. go-plus.json http://purl.obolibrary.org/obo/GO_0005545 GO:0005546 biolink:MolecularActivity phosphatidylinositol-4,5-bisphosphate binding Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions. go-plus.json PtdIns(4,5)P2 binding|PIP2 binding|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding|phosphatidylinositol 4,5-bisphosphate binding http://purl.obolibrary.org/obo/GO_0005546 GO:0005543 biolink:MolecularActivity phospholipid binding Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. go-plus.json http://purl.obolibrary.org/obo/GO_0005543 CHEBI:57758 biolink:ChemicalSubstance N(3)-(carboxylatoformyl)-L-2,3-diaminopropionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57758 chebi_ph7_3 GO:0005544 biolink:MolecularActivity calcium-dependent phospholipid binding Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium. go-plus.json http://purl.obolibrary.org/obo/GO_0005544 CHEBI:57759 biolink:ChemicalSubstance gossypetin-3-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57759 GO:0005541 biolink:MolecularActivity obsolete acyl-CoA or acyl binding OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid. go-plus.json acyl-CoA or acyl binding http://purl.obolibrary.org/obo/GO_0005541 GO:0005542 biolink:MolecularActivity folic acid binding Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. go-plus.json vitamin M binding|folate binding|vitamin B9 binding http://purl.obolibrary.org/obo/GO_0005542 GO:0005540 biolink:MolecularActivity hyaluronic acid binding Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. go-plus.json hyaluronan binding http://purl.obolibrary.org/obo/GO_0005540 CHEBI:5533 biolink:ChemicalSubstance granaticin go-plus.json http://purl.obolibrary.org/obo/CHEBI_5533 chebi_ph7_3 CHEBI:57756 biolink:ChemicalSubstance sphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57756 chebi_ph7_3 CHEBI:18148 biolink:ChemicalSubstance alpha-D-glucose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18148 CHEBI:18149 biolink:ChemicalSubstance aureusidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18149 chebi_ph7_3 CHEBI:57757 biolink:ChemicalSubstance D-threonine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57757 chebi_ph7_3 CHEBI:18146 biolink:ChemicalSubstance (R)-canadine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18146 chebi_ph7_3 CHEBI:57754 biolink:ChemicalSubstance trans-5-O-caffeoyl-D-quinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57754 chebi_ph7_3 CHEBI:18147 biolink:ChemicalSubstance beta-maltose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18147 chebi_ph7_3 CHEBI:57755 biolink:ChemicalSubstance (R)-N-methylcoclaurinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57755 chebi_ph7_3 CHEBI:18144 biolink:ChemicalSubstance all-trans-nonaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18144 CHEBI:57752 biolink:ChemicalSubstance (S)-3-(imidazol-5-yl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57752 chebi_ph7_3 CHEBI:18145 biolink:ChemicalSubstance (+)-alpha-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18145 chebi_ph7_3 CHEBI:57753 biolink:ChemicalSubstance vindolinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57753 chebi_ph7_3 CHEBI:57750 biolink:ChemicalSubstance N(tele)-methyl-L-histidinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_57750 chebi_ph7_3 CHEBI:18142 biolink:ChemicalSubstance N(6')-acetylkanamycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_18142 CHEBI:5530 biolink:ChemicalSubstance gramicidin S go-plus.json http://purl.obolibrary.org/obo/CHEBI_5530 GO:0005516 biolink:MolecularActivity calmodulin binding Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. go-plus.json http://purl.obolibrary.org/obo/GO_0005516 goslim_chembl CHEBI:18184 biolink:ChemicalSubstance 3,5,3'-triiodothyropyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18184 OBO:GOREL_0001019 biolink:OntologyClass results_in_division_of GOREL:0001019 go-plus.json http://purl.obolibrary.org/obo/GOREL_0001019 CHEBI:18185 biolink:ChemicalSubstance gamma-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18185 chebi_ph7_3 GO:0005517 biolink:MolecularActivity obsolete calmodulin inhibitor activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json calmodulin inhibitor activity http://purl.obolibrary.org/obo/GO_0005517 GO:0005514 biolink:MolecularActivity obsolete calcium ion storage activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json calcium ion storage activity http://purl.obolibrary.org/obo/GO_0005514 GO:0005515 biolink:MolecularActivity protein binding Binding to a protein. go-plus.json glycoprotein binding|protein amino acid binding http://purl.obolibrary.org/obo/GO_0005515 goslim_chembl|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics CHEBI:18183 biolink:ChemicalSubstance 5-oxo-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_18183 GO:0005513 biolink:BiologicalProcess detection of calcium ion The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal. go-plus.json calcium ion detection|detection of Ca2+ ion|Ca2+ ion detection|calcium ion sensing http://purl.obolibrary.org/obo/GO_0005513 CHEBI:57747 biolink:ChemicalSubstance 3-(pyrazol-1-yl)-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57747 chebi_ph7_3 CHEBI:33778 biolink:ChemicalSubstance galactonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_33778 CHEBI:33772 biolink:ChemicalSubstance gluconic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33772 CHEBI:57745 biolink:ChemicalSubstance 4-hydroxy-1-pyrroline-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57745 chebi_ph7_3 CHEBI:57746 biolink:ChemicalSubstance 3',5'-cyclic GMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57746 chebi_ph7_3 CHEBI:18179 biolink:ChemicalSubstance phosphoinositide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18179 CHEBI:57743 biolink:ChemicalSubstance L-citrulline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57743 chebi_ph7_3 CHEBI:57744 biolink:ChemicalSubstance 2-(alpha-D-mannosyl)-3-phosphonatoglycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57744 chebi_ph7_3 CHEBI:18177 biolink:ChemicalSubstance N-acetylphenylethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18177 chebi_ph7_3 CHEBI:57741 biolink:ChemicalSubstance phenylethanolaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57741 chebi_ph7_3 CHEBI:57742 biolink:ChemicalSubstance guanidinoacetic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57742 chebi_ph7_3 GO:0005518 biolink:MolecularActivity collagen binding Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). go-plus.json http://purl.obolibrary.org/obo/GO_0005518 CHEBI:57740 biolink:ChemicalSubstance L-5-carboxylatomethylhydantoin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57740 chebi_ph7_3 GO:0005519 biolink:MolecularActivity cytoskeletal regulatory protein binding Binding to a protein involved in modulating the reorganization of the cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0005519 CHEBI:18176 biolink:ChemicalSubstance 2-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18176 GO:0005527 biolink:MolecularActivity macrolide binding Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species. go-plus.json http://purl.obolibrary.org/obo/GO_0005527 GO:0005528 biolink:MolecularActivity FK506 binding Binding to a 23-membered macrolide lactone FK506. go-plus.json FK506-sensitive peptidyl-prolyl cis-trans isomerase http://purl.obolibrary.org/obo/GO_0005528 GO:0005525 biolink:MolecularActivity GTP binding Binding to GTP, guanosine triphosphate. Reactome:R-HSA-167429 go-plus.json http://purl.obolibrary.org/obo/GO_0005525 CHEBI:18171 biolink:ChemicalSubstance 8-O-methylsterigmatocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_18171 chebi_ph7_3 CHEBI:18172 biolink:ChemicalSubstance fluoroacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18172 chebi_ph7_3 CHEBI:57738 biolink:ChemicalSubstance 2-arylpropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57738 chebi_ph7_3 GO:0005523 biolink:MolecularActivity tropomyosin binding Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0005523 GO:0005524 biolink:MolecularActivity ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. Reactome:R-HSA-265682 go-plus.json http://purl.obolibrary.org/obo/GO_0005524 CHEBI:18170 biolink:ChemicalSubstance selenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18170 CHEBI:57739 biolink:ChemicalSubstance phosphatidate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57739 chebi_ph7_3 GO:0005521 biolink:MolecularActivity lamin binding Binding to lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. go-plus.json lamin/chromatin binding http://purl.obolibrary.org/obo/GO_0005521 CHEBI:57736 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57736 chebi_ph7_3 GO:0005522 biolink:MolecularActivity profilin binding Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin. go-plus.json http://purl.obolibrary.org/obo/GO_0005522 CHEBI:57737 biolink:ChemicalSubstance D-xylulose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57737 chebi_ph7_3 GO:0005520 biolink:MolecularActivity insulin-like growth factor binding Binding to an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it. go-plus.json IGF binding http://purl.obolibrary.org/obo/GO_0005520 goslim_chembl CHEBI:57734 biolink:ChemicalSubstance alpha-D-hexose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57734 chebi_ph7_3 CHEBI:57735 biolink:ChemicalSubstance 2-oxosuccinamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57735 chebi_ph7_3 CHEBI:18168 biolink:ChemicalSubstance 2-oxophytanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18168 CHEBI:57732 biolink:ChemicalSubstance 4-carboxylato-2-hydroxyhexa-2,4-dienedioate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57732 chebi_ph7_3 CHEBI:18169 biolink:ChemicalSubstance 1D-myo-inositol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18169 CHEBI:57733 biolink:ChemicalSubstance myo-inositol 1,3,4,5,6-pentakisphosphate(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57733 chebi_ph7_3 CHEBI:57730 biolink:ChemicalSubstance 2-hydroxy-4-nitrophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57730 chebi_ph7_3 CHEBI:18167 biolink:ChemicalSubstance alpha-maltose go-plus.json http://purl.obolibrary.org/obo/CHEBI_18167 chebi_ph7_3 CHEBI:57731 biolink:ChemicalSubstance (R)-3-aminoisobutyric acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57731 chebi_ph7_3 GO:0005529 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0005529 CHEBI:18164 biolink:ChemicalSubstance (2S)-2-hydroxyphytanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18164 CHEBI:18165 biolink:ChemicalSubstance isopenicillin N go-plus.json http://purl.obolibrary.org/obo/CHEBI_18165 CHEBI:72447 biolink:ChemicalSubstance 2-deoxystreptamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72447 UBERON:0014621 biolink:AnatomicalEntity cervical spinal cord ventral horn A ventral horn of spinal cord that is part of a cervical spinal cord. go-plus.json cervical spinal cord anterior horn|cervical spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0014621 UBERON:0014620 biolink:AnatomicalEntity cervical spinal cord dorsal horn A dorsal horn of spinal cord that is part of a cervical spinal cord. go-plus.json cervical spinal cord dorsal horn|cervical spinal cord posterior horn http://purl.obolibrary.org/obo/UBERON_0014620 UBERON:0014614 biolink:AnatomicalEntity cervical spinal cord white matter A white matter of spinal cord that is part of a cervical spinal cord. go-plus.json cervical spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0014614 UBERON:0014615 biolink:AnatomicalEntity accessory nerve root A nerve root that is part of a accessory XI nerve. go-plus.json cranial part of the accessory nerve|pars vagalis of nervus accessorius|c11n|cranial portion of eleventh cranial nerve|bulbar part of accessory nerve|cranial part of accessory nerve|nerve XI (cranialis)|bulbar accessory nerve|radices craniales nervi accessorii|root of accessory nerve|cranial accessory nerve|internal branch of accessory nerve|accessory portion of spinal accessory nerve|accessory nerve root http://purl.obolibrary.org/obo/UBERON_0014615 CHEBI:72454 biolink:ChemicalSubstance poly(ribitol phosphate) teichoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72454 CHEBI:72455 biolink:ChemicalSubstance poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72455 UBERON:0014610 biolink:AnatomicalEntity thoracic spinal cord ventral horn A ventral horn of spinal cord that is part of a thoracic spinal cord. go-plus.json thoracic spinal cord ventral horn|thoracic spinal cord anterior horn http://purl.obolibrary.org/obo/UBERON_0014610 UBERON:0014613 biolink:AnatomicalEntity cervical spinal cord gray matter A gray matter of spinal cord that is part of a cervical spinal cord. go-plus.json cervical spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0014613 UBERON:0014609 biolink:AnatomicalEntity thoracic spinal cord dorsal horn A dorsal horn of spinal cord that is part of a thoracic spinal cord. go-plus.json thoracic spinal cord dorsal horn|thoracic spinal cord posterior horn http://purl.obolibrary.org/obo/UBERON_0014609 CHEBI:72453 biolink:ChemicalSubstance poly(glycerol phosphate) teichoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72453 NCBITaxon:1763 biolink:OrganismalEntity Mycobacterium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1763 GO:0000820 biolink:BiologicalProcess regulation of glutamine family amino acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. go-plus.json regulation of glutamine family amino acid metabolism http://purl.obolibrary.org/obo/GO_0000820 NCBITaxon:1760 biolink:OrganismalEntity Actinomycetia go-plus.json Actinobacteria|High GC gram-positive bacteria|high G+C Gram-positive bacteria|Actinomycetes|high GC Gram+ http://purl.obolibrary.org/obo/NCBITaxon_1760 GO:0048800 biolink:BiologicalProcess antennal morphogenesis The process in which the anatomical structures of the antenna are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048800 GO:0048801 biolink:BiologicalProcess antennal joint morphogenesis The process in which the anatomical structures of the antennal joint are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048801 GO:0048802 biolink:BiologicalProcess notum morphogenesis The process in which the anatomical structures of the dorsal part of the body are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048802 NCBITaxon:1762 biolink:OrganismalEntity Mycobacteriaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1762 CHEBI:23495 biolink:ChemicalSubstance cyclopentanols go-plus.json http://purl.obolibrary.org/obo/CHEBI_23495 CHEBI:23493 biolink:ChemicalSubstance cyclopentanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23493 GO:0000829 biolink:MolecularActivity inositol heptakisphosphate kinase activity Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown. Reactome:R-HSA-1855194|Reactome:R-HSA-1855182|Reactome:R-HSA-1855157 go-plus.json http://purl.obolibrary.org/obo/GO_0000829 GO:0000825 biolink:MolecularActivity inositol tetrakisphosphate 6-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. Reactome:R-HSA-1855206|MetaCyc:RXN-7184 go-plus.json inositol 1,3,4,5-tetrakisphosphate 6-kinase activity|1D-myo-inositol-tetrakisphosphate 6-kinase activity http://purl.obolibrary.org/obo/GO_0000825 GO:0048803 biolink:BiologicalProcess imaginal disc-derived male genitalia morphogenesis The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc. go-plus.json male genital morphogenesis http://purl.obolibrary.org/obo/GO_0048803 GO:0000826 biolink:MolecularActivity obsolete inositol pyrophosphate synthase activity OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds. go-plus.json inositol diphosphate synthase activity|inositol pyrophosphate synthase activity http://purl.obolibrary.org/obo/GO_0000826 GO:0048804 biolink:BiologicalProcess imaginal disc-derived female genitalia morphogenesis The process in which the anatomical structures of female genitalia are generated and organized from the genital disc. go-plus.json female genital morphogenesis http://purl.obolibrary.org/obo/GO_0048804 GO:0000827 biolink:MolecularActivity inositol-1,3,4,5,6-pentakisphosphate kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown. EC:2.7.4.21|Reactome:R-HSA-1855181|Reactome:R-HSA-1855223 go-plus.json http://purl.obolibrary.org/obo/GO_0000827 GO:0048805 biolink:BiologicalProcess imaginal disc-derived genitalia morphogenesis The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc. go-plus.json genital morphogenesis http://purl.obolibrary.org/obo/GO_0048805 GO:0000828 biolink:MolecularActivity inositol hexakisphosphate kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown. Reactome:R-HSA-1855207|Reactome:R-HSA-1855227|Reactome:R-HSA-1855216 go-plus.json http://purl.obolibrary.org/obo/GO_0000828 GO:0048806 biolink:BiologicalProcess genitalia development The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. go-plus.json genital development http://purl.obolibrary.org/obo/GO_0048806 GO:0000821 biolink:BiologicalProcess regulation of arginine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. go-plus.json regulation of arginine metabolism http://purl.obolibrary.org/obo/GO_0000821 GO:0048807 biolink:BiologicalProcess female genitalia morphogenesis The process in which the anatomical structures of female genitalia are generated and organized. go-plus.json female genital morphogenesis http://purl.obolibrary.org/obo/GO_0048807 GO:0000822 biolink:MolecularActivity inositol hexakisphosphate binding Binding to inositol hexakisphosphate. go-plus.json InsP6 binding|IP6 binding http://purl.obolibrary.org/obo/GO_0000822 GO:0048808 biolink:BiologicalProcess male genitalia morphogenesis The process in which the anatomical structures of male genitalia are generated and organized. go-plus.json male genital morphogenesis http://purl.obolibrary.org/obo/GO_0048808 GO:0000823 biolink:MolecularActivity inositol-1,4,5-trisphosphate 6-kinase activity Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+). MetaCyc:2.7.1.151-RXN|EC:2.7.1.151|KEGG_REACTION:R05800 go-plus.json inositol polyphosphate multikinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|IpmK|inositol trisphosphate 6-kinase activity http://purl.obolibrary.org/obo/GO_0000823 GO:0048809 biolink:BiologicalProcess analia morphogenesis The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048809 GO:0000824 biolink:MolecularActivity inositol tetrakisphosphate 3-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. Reactome:R-HSA-1855185|RHEA:11856 go-plus.json inositol polyphosphate multikinase activity|inositol 1,4,5,6-tetrakisphosphate 3-kinase activity|IpmK|EC:2.7.1.151|1D-myo-inositol-tetrakisphosphate 3-kinase activity http://purl.obolibrary.org/obo/GO_0000824 GO:0000830 biolink:MolecularActivity inositol hexakisphosphate 4-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0000830 GO:0000831 biolink:MolecularActivity inositol hexakisphosphate 6-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0000831 GO:0048810 biolink:BiologicalProcess female analia morphogenesis The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048810 GO:0048811 biolink:BiologicalProcess male analia morphogenesis The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. go-plus.json http://purl.obolibrary.org/obo/GO_0048811 GO:0048812 biolink:BiologicalProcess neuron projection morphogenesis The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. go-plus.json neurite morphogenesis|neurite biosynthesis|neurite growth|neurite formation http://purl.obolibrary.org/obo/GO_0048812 GO:0048813 biolink:BiologicalProcess dendrite morphogenesis The process in which the anatomical structures of a dendrite are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048813 NCBITaxon:1773 biolink:OrganismalEntity Mycobacterium tuberculosis go-plus.json Bacillus tuberculosis|Bacterium tuberculosis|Mycobacterium tuberculosis var. hominis|Mycobacterium tuberculosis variant tuberculosis|Mycobacterium tuberculosis typus humanus http://purl.obolibrary.org/obo/NCBITaxon_1773 GO:0048814 biolink:BiologicalProcess regulation of dendrite morphogenesis Any process that modulates the frequency, rate or extent of dendrite morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0048814 GO:0000836 biolink:CellularComponent Hrd1p ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78). go-plus.json HRD1 ubiquitin ligase complex http://purl.obolibrary.org/obo/GO_0000836 GO:0048815 biolink:BiologicalProcess hermaphrodite genitalia morphogenesis The process in which the anatomical structures of hermaphrodite genitalia are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048815 GO:0000837 biolink:CellularComponent Doa10p ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p. go-plus.json Ssm4p ubiquitin ligase complex http://purl.obolibrary.org/obo/GO_0000837 GO:0000838 biolink:CellularComponent Hrd1p ubiquitin ligase ERAD-M complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. go-plus.json http://purl.obolibrary.org/obo/GO_0000838 GO:0048816 biolink:BiologicalProcess ocellus morphogenesis The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects. go-plus.json http://purl.obolibrary.org/obo/GO_0048816 GO:0000839 biolink:CellularComponent Hrd1p ubiquitin ligase ERAD-L complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. go-plus.json http://purl.obolibrary.org/obo/GO_0000839 GO:0048817 biolink:BiologicalProcess negative regulation of hair follicle maturation Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation. go-plus.json downregulation of hair follicle maturation|down regulation of hair follicle maturation|inhibition of hair follicle maturation|down-regulation of hair follicle maturation http://purl.obolibrary.org/obo/GO_0048817 GO:0048818 biolink:BiologicalProcess positive regulation of hair follicle maturation Any process that activates or increases the frequency, rate or extent of hair follicle maturation. go-plus.json upregulation of hair follicle maturation|stimulation of hair follicle maturation|activation of hair follicle maturation|up-regulation of hair follicle maturation|up regulation of hair follicle maturation http://purl.obolibrary.org/obo/GO_0048818 GO:0000832 biolink:MolecularActivity inositol hexakisphosphate 5-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate. RHEA:12793|EC:2.7.4.21|MetaCyc:2.7.1.152-RXN|KEGG_REACTION:R09087 go-plus.json ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0000832 GO:0048819 biolink:BiologicalProcess regulation of hair follicle maturation Any process that modulates the frequency, rate or extent of hair follicle maturation. go-plus.json http://purl.obolibrary.org/obo/GO_0048819 GO:0000833 biolink:MolecularActivity inositol heptakisphosphate 4-kinase activity Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate. go-plus.json IP7 4-kinase activity|diphosphoinositol-pentakisphosphate 4-kinase activity http://purl.obolibrary.org/obo/GO_0000833 GO:0000834 biolink:MolecularActivity inositol heptakisphosphate 6-kinase activity Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0000834 GO:0000835 biolink:CellularComponent ER ubiquitin ligase complex A ubiquitin ligase complex found in the ER. go-plus.json http://purl.obolibrary.org/obo/GO_0000835 GO:0048820 biolink:BiologicalProcess hair follicle maturation A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0048820 GO:0048821 biolink:BiologicalProcess erythrocyte development The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. go-plus.json RBC development|red blood cell development http://purl.obolibrary.org/obo/GO_0048821 UBERON:0000017 biolink:AnatomicalEntity exocrine pancreas The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. go-plus.json exocrine part of pancreas|exocrine component of pancreas|pars exocrina pancreatis|exocrine pancreas http://purl.obolibrary.org/obo/UBERON_0000017 GO:0048822 biolink:BiologicalProcess enucleate erythrocyte development The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json enucleate red blood cell development|enucleate RBC development http://purl.obolibrary.org/obo/GO_0048822 UBERON:0000018 biolink:AnatomicalEntity compound eye A light sensing organ composed of ommatidia go-plus.json Komplexauge|faceted eye|adult compound eye|insect eye|zusammengesetztes Auge|Facettenauge http://purl.obolibrary.org/obo/UBERON_0000018 GO:0048823 biolink:BiologicalProcess nucleate erythrocyte development The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json nucleate RBC development|nucleate red blood cell development http://purl.obolibrary.org/obo/GO_0048823 UBERON:0000019 biolink:AnatomicalEntity camera-type eye An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. go-plus.json eye|vertebrate eye|orbital part of face|eyes|camera-type eye plus associated structures|orbital region|regio orbitalis http://purl.obolibrary.org/obo/UBERON_0000019 CHEBI:23478 biolink:ChemicalSubstance cyclohexanedione go-plus.json http://purl.obolibrary.org/obo/CHEBI_23478 GO:0048824 biolink:BiologicalProcess pigment cell precursor differentiation The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor. go-plus.json chromatophore precursor differentiation http://purl.obolibrary.org/obo/GO_0048824 CHEBI:23470 biolink:ChemicalSubstance cyclohexadienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23470 GO:0000807 biolink:CellularComponent Z chromosome The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females. Wikipedia:ZW_sex-determination_system go-plus.json http://purl.obolibrary.org/obo/GO_0000807 GO:0000808 biolink:CellularComponent origin recognition complex A multisubunit complex that is located at the replication origins of a chromosome. Wikipedia:Origin_recognition_complex go-plus.json origin of replication recognition complex|ORC http://purl.obolibrary.org/obo/GO_0000808 goslim_pir GO:0000809 biolink:CellularComponent cytoplasmic origin of replication recognition complex A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm. go-plus.json cytoplasmic ORC|prokaryotic ORC http://purl.obolibrary.org/obo/GO_0000809 UBERON:0000024 biolink:AnatomicalEntity forelimb wing Forelimb that is used to produce lift for flight through the air. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000024 GO:0048825 biolink:BiologicalProcess cotyledon development The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling. go-plus.json http://purl.obolibrary.org/obo/GO_0048825 GO:0000803 biolink:CellularComponent sex chromosome A chromosome involved in sex determination. go-plus.json http://purl.obolibrary.org/obo/GO_0000803 GO:0000804 biolink:CellularComponent W chromosome The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females. Wikipedia:ZW_sex-determination_system go-plus.json http://purl.obolibrary.org/obo/GO_0000804 GO:0048826 biolink:BiologicalProcess cotyledon morphogenesis The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling. go-plus.json http://purl.obolibrary.org/obo/GO_0048826 UBERON:0000025 biolink:AnatomicalEntity tube Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. go-plus.json duct|anatomical tube http://purl.obolibrary.org/obo/UBERON_0000025 GO:0048827 biolink:BiologicalProcess phyllome development The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants. go-plus.json http://purl.obolibrary.org/obo/GO_0048827 UBERON:0000026 biolink:AnatomicalEntity appendage Major subdivision of an organism that protrudes from the body[DOS, CARO]. go-plus.json extremity|appendages|extremitaet|limbs/digits/tail http://purl.obolibrary.org/obo/UBERON_0000026 GO:0000805 biolink:CellularComponent X chromosome The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males. Wikipedia:X_chromosome go-plus.json http://purl.obolibrary.org/obo/GO_0000805 GO:0000806 biolink:CellularComponent Y chromosome The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males. Wikipedia:Y_chromosome go-plus.json http://purl.obolibrary.org/obo/GO_0000806 GO:0048828 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048828 UBERON:0000020 biolink:AnatomicalEntity sense organ An organ that is capable of transducing sensory stimulus to the nervous system. go-plus.json organ of sensory organ system|sensor|sensory organ|sensillum|sensory organ system organ|organ of sense organ system|organ of sensory system|Sinnesorgan|sense organ system organ|sensory system organ http://purl.obolibrary.org/obo/UBERON_0000020 GO:0048829 biolink:BiologicalProcess root cap development The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant. go-plus.json http://purl.obolibrary.org/obo/GO_0048829 GO:0000800 biolink:CellularComponent lateral element A proteinaceous core found between sister chromatids during meiotic prophase. go-plus.json axial element http://purl.obolibrary.org/obo/GO_0000800 UBERON:0000021 biolink:AnatomicalEntity cutaneous appendage Anatomical projection that protrudes from the skin. Examples: hair, nail, feather, claw, hoof, horn, wattle, spur, beak, antler, bristle and some scales. go-plus.json epidermal appendage|skin appendage|epidermal growth http://purl.obolibrary.org/obo/UBERON_0000021 OBA:VT0005388 biolink:OntologyClass respiratory system trait The quality when measured in respiratory system. go-plus.json http://purl.obolibrary.org/obo/OBA_VT0005388 GO:0000801 biolink:CellularComponent central element A structural unit of the synaptonemal complex found between the lateral elements. go-plus.json http://purl.obolibrary.org/obo/GO_0000801 UBERON:0000023 biolink:AnatomicalEntity wing Appendage that is shaped in order to produce lift for flight through the air. go-plus.json aliform appendage http://purl.obolibrary.org/obo/UBERON_0000023 GO:0000802 biolink:CellularComponent transverse filament A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them. go-plus.json http://purl.obolibrary.org/obo/GO_0000802 GO:1902906 biolink:BiologicalProcess proteasome storage granule assembly The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule. go-plus.json PSG formation|PSG assembly|proteasome storage granule formation|sequestration of proteasome core complex in proteasome storage granule http://purl.obolibrary.org/obo/GO_1902906 GO:1902907 biolink:BiologicalProcess proteasome storage granule disassembly The disaggregation of a proteasome storage granule into its constituent components. go-plus.json PSG disassembly http://purl.obolibrary.org/obo/GO_1902907 GO:1902904 biolink:BiologicalProcess negative regulation of supramolecular fiber organization Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. go-plus.json down regulation of fibril organisation|downregulation of fibril organisation|down regulation of fibril organization|downregulation of fibril organization|negative regulation of fibril organisation|down-regulation of fibril organisation|inhibition of fibril organisation|down-regulation of fibril organization|inhibition of fibril organization http://purl.obolibrary.org/obo/GO_1902904 GO:0048830 biolink:BiologicalProcess adventitious root development The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot. go-plus.json http://purl.obolibrary.org/obo/GO_0048830 GO:1902905 biolink:BiologicalProcess positive regulation of supramolecular fiber organization Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. go-plus.json upregulation of fibril organization|activation of fibril organisation|up regulation of fibril organisation|positive regulation of fibril organisation|activation of fibril organization|up regulation of fibril organization|up-regulation of fibril organisation|up-regulation of fibril organization|upregulation of fibril organisation http://purl.obolibrary.org/obo/GO_1902905 GO:0048831 biolink:BiologicalProcess regulation of shoot system development Any process that modulates the frequency, rate or extent of shoot development. go-plus.json regulation of shoot development http://purl.obolibrary.org/obo/GO_0048831 UBERON:0000006 biolink:AnatomicalEntity islet of Langerhans the clusters of hormone-producing cells that are scattered throughout the pancreas go-plus.json islets of Langerhans|pancreatic islet|pancreatic insula|island of Langerhans|island of pancreas http://purl.obolibrary.org/obo/UBERON_0000006 GO:1902902 biolink:BiologicalProcess negative regulation of autophagosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly. go-plus.json inhibition of autophagic vacuole assembly|down regulation of autophagic vacuole formation|inhibition of PAS formation|downregulation of autophagosome biosynthesis|negative regulation of autophagic vacuole assembly|down-regulation of autophagosome formation|negative regulation of autophagosome formation|inhibition of autophagic vacuole formation|down regulation of autophagosome biosynthesis|down regulation of PAS formation|inhibition of autophagosome biosynthesis|downregulation of PAS formation|down regulation of autophagic vacuole assembly|inhibition of autophagosome formation|downregulation of autophagic vacuole assembly|negative regulation of autophagic vacuole formation|down-regulation of autophagic vacuole formation|down-regulation of PAS formation|negative regulation of PAS formation|down regulation of autophagosome formation|down-regulation of autophagic vacuole assembly|negative regulation of autophagosome biosynthesis|down-regulation of autophagosome biosynthesis|downregulation of autophagic vacuole formation|downregulation of autophagosome formation http://purl.obolibrary.org/obo/GO_1902902 GO:0048832 biolink:BiologicalProcess specification of plant organ number The regionalization process that modulates the quantity of a particular type of plant organ. go-plus.json http://purl.obolibrary.org/obo/GO_0048832 UBERON:0000007 biolink:AnatomicalEntity pituitary gland The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]. go-plus.json pituitary body|Hp|glandula pituitaria|hypophysis cerebri|hypophysis|pituitary http://purl.obolibrary.org/obo/UBERON_0000007 GO:1902903 biolink:BiologicalProcess regulation of supramolecular fiber organization Any process that modulates the frequency, rate or extent of supramolecular fiber organization. go-plus.json regulation of fibril organisation http://purl.obolibrary.org/obo/GO_1902903 GO:0048833 biolink:BiologicalProcess specification of floral organ number Any process that modulates the number of floral organs formed in a floral whorl. go-plus.json http://purl.obolibrary.org/obo/GO_0048833 GO:1902900 biolink:BiologicalProcess gut granule assembly The aggregation, arrangement and bonding together of a set of components to form a gut granule. go-plus.json gut granule formation|gut granule biogenesis http://purl.obolibrary.org/obo/GO_1902900 GO:0048834 biolink:BiologicalProcess specification of petal number Any process that modulates the number of petals formed in a flower. go-plus.json http://purl.obolibrary.org/obo/GO_0048834 GO:1902901 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion Any positive regulation of transcription from RNA polymerase II promoter that is involved in stress response to cadmium ion. go-plus.json positive regulation of transcription from Pol II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up-regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from Pol II promoter involved in response to cadmium ion stress|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|activation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in stress response to cadmium ion|upregulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from Pol II promoter involved in stress response to cadmium ion|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|activation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in response to cadmium ion stress|stimulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|stimulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of global transcription from Pol II promoter involved in stress response to cadmium ion|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion http://purl.obolibrary.org/obo/GO_1902901 GO:0048835 biolink:BiologicalProcess specification of decreased petal number Any process that reduces the number of petals produced in a developing flower. go-plus.json http://purl.obolibrary.org/obo/GO_0048835 UBERON:0000009 biolink:AnatomicalEntity submucosa A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]. go-plus.json submucous layer|tunica submucosa|organ submucosa|submucosa of region of organ|submucosa of organ|region of submucosa|tela submucosa http://purl.obolibrary.org/obo/UBERON_0000009 CHEBI:23480 biolink:ChemicalSubstance cyclohexanols go-plus.json http://purl.obolibrary.org/obo/CHEBI_23480 CHEBI:23483 biolink:ChemicalSubstance cyclohexenecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23483 CHEBI:23482 biolink:ChemicalSubstance cyclohexanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_23482 GO:0000818 biolink:CellularComponent nuclear MIS12/MIND complex A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1. go-plus.json Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex|MIND complex http://purl.obolibrary.org/obo/GO_0000818 GO:0000819 biolink:BiologicalProcess sister chromatid segregation The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. go-plus.json http://purl.obolibrary.org/obo/GO_0000819 UBERON:0014649 biolink:AnatomicalEntity white matter of medulla oblongata A white matter that is part of a medulla oblongata. go-plus.json substantia alba medullae oblongatae|white matter of medulla|white substance of medulla|medullary white matter http://purl.obolibrary.org/obo/UBERON_0014649 GO:0048836 biolink:BiologicalProcess specification of increased petal number Any process that increases the number of petals produced in a developing flower. go-plus.json http://purl.obolibrary.org/obo/GO_0048836 UBERON:0000013 biolink:AnatomicalEntity sympathetic nervous system The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]. go-plus.json sympathetic nervous system|sympathetic part of autonomic division of nervous system|pars sympathica divisionis autonomici systematis nervosi|pars sympathica divisionis autonomici systematis nervosi http://purl.obolibrary.org/obo/UBERON_0000013 GO:0000814 biolink:CellularComponent ESCRT II complex An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. go-plus.json endosomal sorting complex required for transport http://purl.obolibrary.org/obo/GO_0000814 GO:0048837 biolink:BiologicalProcess sorocarp sorus development The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp. go-plus.json sorocarp spore head morphogenesis|sorocarp sorus formation|sorocarp spore head formation http://purl.obolibrary.org/obo/GO_0048837 UBERON:0000014 biolink:AnatomicalEntity zone of skin Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. go-plus.json skin|region of skin|skin region|skin zone|portion of skin http://purl.obolibrary.org/obo/UBERON_0000014 GO:0000815 biolink:CellularComponent ESCRT III complex An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes. go-plus.json endosomal sorting complex required for transport http://purl.obolibrary.org/obo/GO_0000815 UBERON:0000015 biolink:AnatomicalEntity non-material anatomical boundary A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. go-plus.json anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000015 GO:0048838 biolink:BiologicalProcess release of seed from dormancy The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release. go-plus.json http://purl.obolibrary.org/obo/GO_0048838 GO:0000816 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000816 GO:0000817 biolink:CellularComponent COMA complex A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p. go-plus.json Ctf19p-Okp1p-Mcm1p-Ame1p complex http://purl.obolibrary.org/obo/GO_0000817 UBERON:0000016 biolink:AnatomicalEntity endocrine pancreas The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. go-plus.json pars endocrina pancreatis|endocrine part of pancreas|islets of Langerhans part of pancreas|endocrine pancreas http://purl.obolibrary.org/obo/UBERON_0000016 GO:0048839 biolink:BiologicalProcess inner ear development The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048839 GO:0000810 biolink:MolecularActivity diacylglycerol diphosphate phosphatase activity Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate. RHEA:27449|EC:3.1.3.81|MetaCyc:RXN-11277 go-plus.json diacylglycerol pyrophosphate phosphatase activity|DGPP phosphohydrolase activity|DGPP phosphatase activity http://purl.obolibrary.org/obo/GO_0000810 UBERON:0000010 biolink:AnatomicalEntity peripheral nervous system A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. go-plus.json PNS|pars peripherica|systema nervosum periphericum http://purl.obolibrary.org/obo/UBERON_0000010 GO:0000811 biolink:CellularComponent GINS complex A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks. go-plus.json Go, Ichi, Ni and San complex http://purl.obolibrary.org/obo/GO_0000811 GO:0000812 biolink:CellularComponent Swr1 complex A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. go-plus.json SWR-C http://purl.obolibrary.org/obo/GO_0000812 GO:1902908 biolink:BiologicalProcess regulation of melanosome transport Any process that modulates the frequency, rate or extent of melanosome transport. go-plus.json http://purl.obolibrary.org/obo/GO_1902908 UBERON:0000011 biolink:AnatomicalEntity parasympathetic nervous system The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia[GO]. go-plus.json parasympathetic part of autonomic division of nervous system|PNS - parasympathetic|pars parasympathica divisionis autonomici systematis nervosi|pars parasympathica divisionis autonomici systematis nervosi http://purl.obolibrary.org/obo/UBERON_0000011 UBERON:0000012 biolink:AnatomicalEntity somatic nervous system Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors. go-plus.json somatic part of peripheral nervous system|somatic nervous system, somatic division|PNS - somatic|somatic peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0000012 GO:1902909 biolink:BiologicalProcess negative regulation of melanosome transport Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport. go-plus.json down-regulation of melanosome transport|downregulation of melanosome transport|down regulation of melanosome transport|inhibition of melanosome transport http://purl.obolibrary.org/obo/GO_1902909 GO:0000813 biolink:CellularComponent ESCRT I complex An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes. go-plus.json endosomal sorting complex required for transport http://purl.obolibrary.org/obo/GO_0000813 GO:1902917 biolink:BiologicalProcess positive regulation of mating projection assembly Any process that activates or increases the frequency, rate or extent of mating projection assembly. go-plus.json up-regulation of mating projection assembly|activation of mating projection assembly|upregulation of mating projection biogenesis|up-regulation of mating projection biogenesis|up regulation of mating projection assembly|activation of mating projection biogenesis|positive regulation of mating projection biogenesis|upregulation of mating projection assembly|up regulation of mating projection biogenesis http://purl.obolibrary.org/obo/GO_1902917 GO:1902918 biolink:BiologicalProcess poly(5-hydroxyvalerate) metabolic process The chemical reactions and pathways involving poly(5-hydroxyvalerate). go-plus.json poly(5-hydroxyvalerate) metabolism http://purl.obolibrary.org/obo/GO_1902918 GO:0048840 biolink:BiologicalProcess otolith development The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048840 GO:1902915 biolink:BiologicalProcess negative regulation of protein polyubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination. go-plus.json down regulation of protein polyubiquitination|negative regulation of protein polyubiquitylation|down-regulation of protein polyubiquitylation|inhibition of protein polyubiquitination|negative regulation of protein polyubiquitinylation|down-regulation of protein polyubiquitinylation|inhibition of polyubiquitin|downregulation of protein polyubiquitylation|down regulation of protein polyubiquitylation|downregulation of protein polyubiquitinylation|inhibition of protein polyubiquitylation|down regulation of polyubiquitin|down regulation of protein polyubiquitinylation|down-regulation of protein polyubiquitination|inhibition of protein polyubiquitinylation|downregulation of polyubiquitin|downregulation of protein polyubiquitination|down-regulation of polyubiquitin|negative regulation of polyubiquitin http://purl.obolibrary.org/obo/GO_1902915 NCBITaxon:83332 biolink:OrganismalEntity Mycobacterium tuberculosis H37Rv go-plus.json Mycobacterium sp. H37Rv|Mycobacterium tuberculosis str. H37Rv|Mycobacterium tuberculosis strain H37Rv http://purl.obolibrary.org/obo/NCBITaxon_83332 GO:0048841 biolink:BiologicalProcess regulation of axon extension involved in axon guidance Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance. go-plus.json http://purl.obolibrary.org/obo/GO_0048841 GO:0048842 biolink:BiologicalProcess positive regulation of axon extension involved in axon guidance Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance. go-plus.json stimulation of axon extension involved in axon guidance|up-regulation of axon extension involved in axon guidance|activation of axon extension involved in axon guidance|up regulation of axon extension involved in axon guidance|upregulation of axon extension involved in axon guidance http://purl.obolibrary.org/obo/GO_0048842 GO:1902916 biolink:BiologicalProcess positive regulation of protein polyubiquitination Any process that activates or increases the frequency, rate or extent of protein polyubiquitination. go-plus.json activation of protein polyubiquitinylation|upregulation of protein polyubiquitination|up-regulation of polyubiquitin|positive regulation of protein polyubiquitylation|up regulation of protein polyubiquitylation|positive regulation of protein polyubiquitinylation|up regulation of protein polyubiquitinylation|up-regulation of protein polyubiquitination|activation of protein polyubiquitination|upregulation of polyubiquitin|upregulation of protein polyubiquitylation|upregulation of protein polyubiquitinylation|up regulation of polyubiquitin|up regulation of protein polyubiquitination|positive regulation of polyubiquitin|up-regulation of protein polyubiquitylation|activation of protein polyubiquitylation|up-regulation of protein polyubiquitinylation|activation of polyubiquitin http://purl.obolibrary.org/obo/GO_1902916 CHEBI:23453 biolink:ChemicalSubstance cycloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_23453 NCBITaxon:83333 biolink:OrganismalEntity Escherichia coli K-12 go-plus.json Escherichia coli K12 http://purl.obolibrary.org/obo/NCBITaxon_83333 GO:0048843 biolink:BiologicalProcess negative regulation of axon extension involved in axon guidance Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance. go-plus.json down-regulation of axon extension involved in axon guidance|downregulation of axon extension involved in axon guidance|down regulation of axon extension involved in axon guidance|inhibition of axon extension involved in axon guidance http://purl.obolibrary.org/obo/GO_0048843 GO:1902913 biolink:BiologicalProcess positive regulation of neuroepithelial cell differentiation Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation. go-plus.json activation of neuroepithelial cell differentiation|up-regulation of neuroepithelial cell differentiation|up regulation of neuroepithelial cell differentiation|upregulation of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_1902913 GO:1902914 biolink:BiologicalProcess regulation of protein polyubiquitination Any process that modulates the frequency, rate or extent of protein polyubiquitination. go-plus.json regulation of protein polyubiquitylation|regulation of protein polyubiquitinylation|regulation of polyubiquitin http://purl.obolibrary.org/obo/GO_1902914 GO:0048844 biolink:BiologicalProcess artery morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. go-plus.json arteriogenesis|arterial morphogenesis http://purl.obolibrary.org/obo/GO_0048844 GO:1902911 biolink:CellularComponent protein kinase complex A protein complex which is capable of protein kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902911 CHEBI:23456 biolink:ChemicalSubstance cyclodextrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23456 GO:0048845 biolink:BiologicalProcess venous blood vessel morphogenesis The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. go-plus.json venous morphogenesis|vein morphogenesis http://purl.obolibrary.org/obo/GO_0048845 GO:0048846 biolink:BiologicalProcess axon extension involved in axon guidance The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues. go-plus.json http://purl.obolibrary.org/obo/GO_0048846 GO:1902912 biolink:CellularComponent pyruvate kinase complex A protein complex which is capable of pyruvate kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902912 CHEBI:23457 biolink:ChemicalSubstance cyclodiene organochlorine insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23457 GO:1902910 biolink:BiologicalProcess positive regulation of melanosome transport Any process that activates or increases the frequency, rate or extent of melanosome transport. go-plus.json upregulation of melanosome transport|up-regulation of melanosome transport|activation of melanosome transport|up regulation of melanosome transport http://purl.obolibrary.org/obo/GO_1902910 CHEBI:23450 biolink:ChemicalSubstance cyclitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23450 CHEBI:23451 biolink:ChemicalSubstance cyclitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23451 UBERON:0014636 biolink:AnatomicalEntity thoracic spinal cord gray matter A gray matter of spinal cord that is part of a thoracic spinal cord. go-plus.json thoracic spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0014636 UBERON:0014637 biolink:AnatomicalEntity thoracic spinal cord white matter A white matter of spinal cord that is part of a thoracic spinal cord. go-plus.json thoracic spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0014637 UBERON:0014639 biolink:AnatomicalEntity frontal sulcus A sulcus of brain that is part of a frontal cortex. go-plus.json frontal lobe sulci|frontal lobe sulcus http://purl.obolibrary.org/obo/UBERON_0014639 GO:0048847 biolink:BiologicalProcess adenohypophysis formation The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. go-plus.json anterior pituitary gland biosynthesis|anterior pituitary gland formation|anterior pituitary biosynthesis|adenophysis formation|adenophysis biosynthesis|anterior pituitary formation http://purl.obolibrary.org/obo/GO_0048847 UBERON:0000002 biolink:AnatomicalEntity uterine cervix Lower, narrow portion of the uterus where it joins with the top end of the vagina. go-plus.json cervical canal of uterus|cervix uteri|neck of uterus|cervix|cervix of uterus|canalis cervicis uteri|cervical canal|uterine cervix|caudal segment of uterus http://purl.obolibrary.org/obo/UBERON_0000002 UBERON:0000003 biolink:AnatomicalEntity naris Orifice of the olfactory system. The naris is the route by which odorants enter the olfactory system[MAH]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000003 GO:0048848 biolink:BiologicalProcess neurohypophysis morphogenesis The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. go-plus.json neurophysis morphogenesis|posterior pituitary gland morphogenesis|posterior pituitary morphogenesis http://purl.obolibrary.org/obo/GO_0048848 GO:0048849 biolink:BiologicalProcess neurohypophysis formation The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. go-plus.json posterior pituitary gland biosynthesis|neurophysis biosynthesis|posterior pituitary formation|posterior pituitary biosynthesis|neurophysis formation|posterior pituitary gland formation http://purl.obolibrary.org/obo/GO_0048849 UBERON:0000004 biolink:AnatomicalEntity nose The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity. go-plus.json peripheral olfactory organ|nasus|nose|proboscis|olfactory apparatus|nasal sac http://purl.obolibrary.org/obo/UBERON_0000004 UBERON:0000005 biolink:AnatomicalEntity chemosensory organ go-plus.json chemosensory sensory organ http://purl.obolibrary.org/obo/UBERON_0000005 GO:1902919 biolink:BiologicalProcess poly(5-hydroxyvalerate) biosynthetic process The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate). go-plus.json poly(5-hydroxyvalerate) anabolism|poly(5-hydroxyvalerate) synthesis|poly(5-hydroxyvalerate) formation|poly(5-hydroxyvalerate) biosynthesis http://purl.obolibrary.org/obo/GO_1902919 UBERON:0000000 biolink:AnatomicalEntity processual entity An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000000 GO:1902928 biolink:BiologicalProcess inulin biosynthetic process The chemical reactions and pathways resulting in the formation of inulin. go-plus.json inulin biosynthesis|inulin anabolism|inulin synthesis|inulin formation http://purl.obolibrary.org/obo/GO_1902928 GO:0048850 biolink:BiologicalProcess hypophysis morphogenesis The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. go-plus.json pituitary gland morphogenesis http://purl.obolibrary.org/obo/GO_0048850 GO:0048851 biolink:BiologicalProcess hypophysis formation The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands. go-plus.json pituitary gland formation|hypophysis biosynthesis|pituitary gland biosynthesis http://purl.obolibrary.org/obo/GO_0048851 GO:1902929 biolink:CellularComponent plasma membrane of growing cell tip Any plasma membrane part that is part of a growing cell tip. go-plus.json plasma membrane part of growing cell end|plasma membrane part of growing cell tip|growing cell tip plasma membrane part http://purl.obolibrary.org/obo/GO_1902929 CHEBI:23466 biolink:ChemicalSubstance cyclohexadienecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23466 GO:1902926 biolink:BiologicalProcess inulin metabolic process The chemical reactions and pathways involving inulin. go-plus.json inulin metabolism http://purl.obolibrary.org/obo/GO_1902926 GO:0048852 biolink:BiologicalProcess diencephalon morphogenesis The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0048852 GO:1902927 biolink:BiologicalProcess inulin catabolic process The chemical reactions and pathways resulting in the breakdown of inulin. go-plus.json inulin catabolism|inulin degradation|inulin breakdown http://purl.obolibrary.org/obo/GO_1902927 GO:0048853 biolink:BiologicalProcess forebrain morphogenesis The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). go-plus.json prosencephalon morphogenesis http://purl.obolibrary.org/obo/GO_0048853 GO:1902924 biolink:BiologicalProcess poly(hydroxyalkanoate) biosynthetic process from glucose The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose. go-plus.json poly(hydroxyalkanoate) biosynthesis from glucose|poly(hydroxyalkanoate) formation from glucose|poly(hydroxyalkanoate) synthesis from glucose|poly(hydroxyalkanoate) anabolism from glucose http://purl.obolibrary.org/obo/GO_1902924 GO:0048854 biolink:BiologicalProcess brain morphogenesis The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). go-plus.json http://purl.obolibrary.org/obo/GO_0048854 CHEBI:23469 biolink:ChemicalSubstance cyclohexadienediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23469 GO:1902925 biolink:BiologicalProcess poly(hydroxyalkanoate) biosynthetic process from fatty acid The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid. go-plus.json poly(hydroxyalkanoate) anabolism from fatty acid|poly(hydroxyalkanoate) synthesis from fatty acid|poly(hydroxyalkanoate) formation from fatty acid|poly(hydroxyalkanoate) biosynthesis from fatty acid http://purl.obolibrary.org/obo/GO_1902925 GO:0048855 biolink:BiologicalProcess adenohypophysis morphogenesis The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. go-plus.json adenophysis morphogenesis|anterior pituitary morphogenesis|anterior pituitary gland morphogenesis http://purl.obolibrary.org/obo/GO_0048855 GO:1902922 biolink:BiologicalProcess poly(3-hydroxyvalerate) metabolic process The chemical reactions and pathways involving poly(3-hydroxyvalerate). go-plus.json poly(3-hydroxyvalerate) metabolism http://purl.obolibrary.org/obo/GO_1902922 GO:0048856 biolink:BiologicalProcess anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. go-plus.json development of an anatomical structure http://purl.obolibrary.org/obo/GO_0048856 goslim_plant|goslim_generic|goslim_chembl GO:0048857 biolink:BiologicalProcess neural nucleus development The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. go-plus.json http://purl.obolibrary.org/obo/GO_0048857 GO:1902923 biolink:BiologicalProcess poly(3-hydroxyvalerate) biosynthetic process The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate). go-plus.json poly(3-hydroxyvalerate) anabolism|poly(3-hydroxyvalerate) biosynthesis|poly(3-hydroxyvalerate) synthesis|poly(3-hydroxyvalerate) formation http://purl.obolibrary.org/obo/GO_1902923 CHEBI:23468 biolink:ChemicalSubstance cyclohexadienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23468 GO:1902920 biolink:BiologicalProcess poly(hydroxyvalerate) metabolic process The chemical reactions and pathways involving poly(hydroxyvalerate). go-plus.json poly(hydroxyvalerate) metabolism http://purl.obolibrary.org/obo/GO_1902920 GO:1902921 biolink:BiologicalProcess poly(hydroxyvalerate) biosynthetic process The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate). go-plus.json poly(hydroxyvalerate) anabolism|poly(hydroxyvalerate) synthesis|poly(hydroxyvalerate) formation|poly(hydroxyvalerate) biosynthesis http://purl.obolibrary.org/obo/GO_1902921 UBERON:0014635 biolink:AnatomicalEntity dorsal nerve root of cervical spinal cord A dorsal root of spinal cord that overlaps a cervical spinal cord. go-plus.json posterior nerve root of cervical spinal cord|dorsal nerve root of cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0014635 GO:0048858 biolink:BiologicalProcess cell projection morphogenesis The process in which the anatomical structures of a cell projection are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048858 GO:0048859 biolink:BiologicalProcess formation of anatomical boundary The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0048859 GO:0034217 biolink:BiologicalProcess ascospore wall chitin biosynthetic process The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores. go-plus.json ascospore wall chitin biosynthesis|ascospore wall chitin anabolism|ascospore wall chitin synthesis|ascospore wall chitin formation http://purl.obolibrary.org/obo/GO_0034217 GO:0034218 biolink:BiologicalProcess ascospore wall chitin metabolic process The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores. go-plus.json ascospore wall chitin metabolism http://purl.obolibrary.org/obo/GO_0034218 CHEBI:443725 biolink:ChemicalSubstance fosmidomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_443725 GO:0034219 biolink:BiologicalProcess carbohydrate transmembrane transport The process in which a carbohydrate is transported across a membrane. go-plus.json transmembrane carbohydrate transport|carbohydrate membrane transport http://purl.obolibrary.org/obo/GO_0034219 GO:0010248 biolink:BiologicalProcess establishment or maintenance of transmembrane electrochemical gradient The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010248 GO:0010249 biolink:BiologicalProcess auxin conjugate metabolic process The chemical reactions and pathways involving auxin conjugates, a bound form of auxin. go-plus.json auxin conjugate metabolism http://purl.obolibrary.org/obo/GO_0010249 GO:0009260 biolink:BiologicalProcess ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json ribonucleotide biosynthesis|ribonucleotide anabolism|ribonucleotide synthesis|ribonucleotide formation http://purl.obolibrary.org/obo/GO_0009260 GO:0009261 biolink:BiologicalProcess ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json ribonucleotide catabolism|ribonucleotide degradation|ribonucleotide breakdown http://purl.obolibrary.org/obo/GO_0009261 GO:0009262 biolink:BiologicalProcess deoxyribonucleotide metabolic process The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json deoxyribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009262 GO:0009263 biolink:BiologicalProcess deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json deoxyribonucleotide anabolism|deoxyribonucleotide synthesis|deoxyribonucleotide formation|deoxyribonucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0009263 GO:0009253 biolink:BiologicalProcess peptidoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. go-plus.json murein catabolism|peptidoglycan degradation|murein catabolic process|peptidoglycan breakdown|peptidoglycan catabolism http://purl.obolibrary.org/obo/GO_0009253 GO:0010242 biolink:MolecularActivity oxygen evolving activity Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle. EC:1.10.3.9|MetaCyc:PSII-RXN|MetaCyc:RXN0-5265|RHEA:36359 go-plus.json photosynthetic water oxidation http://purl.obolibrary.org/obo/GO_0010242 GO:0009254 biolink:BiologicalProcess peptidoglycan turnover The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall. go-plus.json murein turnover http://purl.obolibrary.org/obo/GO_0009254 GO:0010243 biolink:BiologicalProcess response to organonitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. go-plus.json response to organic nitrogen http://purl.obolibrary.org/obo/GO_0010243 GO:0034210 biolink:BiologicalProcess sterol deacetylation The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_0034210 CHEBI:370252 biolink:ChemicalSubstance xylitol 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_370252 chebi_ph7_3 GO:0009255 biolink:BiologicalProcess Entner-Doudoroff pathway through 6-phosphogluconate A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it. MetaCyc:ENTNER-DOUDOROFF-PWY-I go-plus.json http://purl.obolibrary.org/obo/GO_0009255 GO:0010240 biolink:CellularComponent plastid pyruvate dehydrogenase complex Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria. go-plus.json dehydrogenase complex http://purl.obolibrary.org/obo/GO_0010240 GO:0034211 biolink:MolecularActivity GTP-dependent protein kinase activity GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0034211 GO:0010241 biolink:BiologicalProcess ent-kaurene oxidation to kaurenoic acid The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase. go-plus.json ent-kaurene oxidation to kaurenoic acid by ent-kaurene oxidase|ent-kaurene oxidation to ent-kaurenoate|ent-kaurene oxidation to ent-kaur-16-en-19-oate http://purl.obolibrary.org/obo/GO_0010241 GO:0034212 biolink:MolecularActivity peptide N-acetyltransferase activity Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide. Reactome:R-HSA-3371554 go-plus.json http://purl.obolibrary.org/obo/GO_0034212 GO:0009256 biolink:BiologicalProcess 10-formyltetrahydrofolate metabolic process The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. go-plus.json 10-formyl-THF metabolic process|10-formyl-THF metabolism|10-formyltetrahydrofolate metabolism http://purl.obolibrary.org/obo/GO_0009256 GO:0009257 biolink:BiologicalProcess 10-formyltetrahydrofolate biosynthetic process The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. MetaCyc:PWY-3841|MetaCyc:1CMET2-PWY go-plus.json 10-formyltetrahydrofolate anabolism|10-formyltetrahydrofolate synthesis|10-formyltetrahydrofolate formation|10-formyl-THF biosynthetic process|10-formyl-THF biosynthesis|10-formyltetrahydrofolate biosynthesis http://purl.obolibrary.org/obo/GO_0009257 GO:0010246 biolink:BiologicalProcess rhamnogalacturonan I biosynthetic process The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide. go-plus.json rhamnogalacturonan I synthesis|rhamnogalacturonan I formation|rhamnogalacturonan I biosynthesis|rhamnogalacturonan I anabolism http://purl.obolibrary.org/obo/GO_0010246 GO:0034213 biolink:BiologicalProcess quinolinate catabolic process The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. go-plus.json quinolinate degradation|quinolinate breakdown|quinolinate catabolism http://purl.obolibrary.org/obo/GO_0034213 GO:0010247 biolink:BiologicalProcess detection of phosphate ion The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal. go-plus.json phosphate ion sensing|phosphate ion detection|phosphate ion perception http://purl.obolibrary.org/obo/GO_0010247 GO:0034214 biolink:BiologicalProcess protein hexamerization The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits. go-plus.json protein hexamer biosynthesis|protein hexamer biosynthetic process|protein hexamer assembly|protein hexamer formation http://purl.obolibrary.org/obo/GO_0034214 GO:0009258 biolink:BiologicalProcess 10-formyltetrahydrofolate catabolic process The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. go-plus.json 10-formyl-THF catabolic process|10-formyl-THF catabolism|10-formyltetrahydrofolate catabolism|10-formyltetrahydrofolate degradation|10-formyltetrahydrofolate breakdown http://purl.obolibrary.org/obo/GO_0009258 GO:0009259 biolink:BiologicalProcess ribonucleotide metabolic process The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json ribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009259 GO:0034215 biolink:MolecularActivity thiamine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). go-plus.json thiamin:hydrogen symporter activity|thiamin:proton symporter activity|thiamine:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0034215 GO:0010244 biolink:BiologicalProcess response to low fluence blue light stimulus by blue low-fluence system Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes. go-plus.json response to low fluence blue light by blf system|response to low fluence blue light http://purl.obolibrary.org/obo/GO_0010244 GO:0034216 biolink:MolecularActivity high-affinity thiamine:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high-affinity thiamin:hydrogen symporter activity|high-affinity thiamin:proton symporter activity|high affinity thiamin:hydrogen symporter activity|high-affinity thiamine:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0034216 CHEBI:1800 biolink:ChemicalSubstance 4-chloro-2-methylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1800 chebi_ph7_3 GO:0010245 biolink:BiologicalProcess radial microtubular system formation Formation of radial microtubular systems during male meiotic cytokinesis in plants. go-plus.json http://purl.obolibrary.org/obo/GO_0010245 GO:0034206 biolink:CellularComponent enhanceosome A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation. Wikipedia:Enhanceosome go-plus.json http://purl.obolibrary.org/obo/GO_0034206 GO:0034207 biolink:BiologicalProcess steroid acetylation The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_0034207 GO:0034208 biolink:BiologicalProcess steroid deacetylation The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_0034208 GO:0010259 biolink:BiologicalProcess multicellular organism aging An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700). go-plus.json http://purl.obolibrary.org/obo/GO_0010259 GO:0034209 biolink:BiologicalProcess sterol acetylation The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. go-plus.json http://purl.obolibrary.org/obo/GO_0034209 GO:0009270 biolink:BiologicalProcess response to humidity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere. go-plus.json http://purl.obolibrary.org/obo/GO_0009270 GO:0009271 biolink:BiologicalProcess phage shock A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage. go-plus.json http://purl.obolibrary.org/obo/GO_0009271 GO:0009272 biolink:BiologicalProcess fungal-type cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin. go-plus.json chitin- and beta-glucan-containing cell wall biogenesis|fungal-type cell wall synthesis|fungal-type cell wall biosynthetic process|fungal-type cell wall formation|fungal-type cell wall anabolism http://purl.obolibrary.org/obo/GO_0009272 GO:0009273 biolink:BiologicalProcess peptidoglycan-based cell wall biogenesis The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli. go-plus.json cell wall biosynthetic process|cell wall anabolism|cell wall assembly|cell envelope biosynthetic process|cell envelope biosynthesis|cell wall synthesis|cell wall formation http://purl.obolibrary.org/obo/GO_0009273 GO:0009274 biolink:CellularComponent peptidoglycan-based cell wall A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli. go-plus.json envelope|murein sacculus|peptidoglycan http://purl.obolibrary.org/obo/GO_0009274 GO:0009264 biolink:BiologicalProcess deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json deoxyribonucleotide catabolism|deoxyribonucleotide degradation|deoxyribonucleotide breakdown http://purl.obolibrary.org/obo/GO_0009264 GO:0010253 biolink:BiologicalProcess UDP-rhamnose biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-3261 go-plus.json UDP-rhamnose synthesis|UDP-rhamnose formation|UDP-rhamnose biosynthesis|UDP-rhamnose anabolism http://purl.obolibrary.org/obo/GO_0010253 GO:0009265 biolink:BiologicalProcess 2'-deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json 2'-deoxyribonucleotide formation|2'-deoxyribonucleotide anabolism|2'-deoxyribonucleotide biosynthesis|2'-deoxyribonucleotide synthesis http://purl.obolibrary.org/obo/GO_0009265 GO:0010254 biolink:BiologicalProcess nectary development The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0010254 GO:0034200 biolink:MolecularActivity D,D-heptose 1,7-bisphosphate phosphatase activity Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate. RHEA:28518|MetaCyc:RXN0-4361 go-plus.json http://purl.obolibrary.org/obo/GO_0034200 GO:0009266 biolink:BiologicalProcess response to temperature stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. go-plus.json response to thermal stimulus http://purl.obolibrary.org/obo/GO_0009266 GO:0010251 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010251 GO:0010252 biolink:BiologicalProcess auxin homeostasis A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation. go-plus.json http://purl.obolibrary.org/obo/GO_0010252 GO:0034201 biolink:BiologicalProcess response to oleic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus. go-plus.json response to oleate http://purl.obolibrary.org/obo/GO_0034201 GO:0009267 biolink:BiologicalProcess cellular response to starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. go-plus.json http://purl.obolibrary.org/obo/GO_0009267 GO:0034202 biolink:MolecularActivity glycolipid floppase activity Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. Reactome:R-HSA-4570573|Reactome:R-HSA-446212 go-plus.json glycolipid-translocating activity|glycolipid floppase activity (cytosolic to exoplasmic leaftlet)|ATP-dependent intramembrane glycolipid transporter activity|ATPase-coupled intramembrane glycolipid transporter activity http://purl.obolibrary.org/obo/GO_0034202 GO:0009268 biolink:BiologicalProcess response to pH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json http://purl.obolibrary.org/obo/GO_0009268 GO:0010257 biolink:BiologicalProcess NADH dehydrogenase complex assembly The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0010257 GO:0034203 biolink:BiologicalProcess glycolipid translocation The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go-plus.json http://purl.obolibrary.org/obo/GO_0034203 GO:0010258 biolink:BiologicalProcess NADH dehydrogenase complex (plastoquinone) assembly The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I. go-plus.json http://purl.obolibrary.org/obo/GO_0010258 GO:0009269 biolink:BiologicalProcess response to desiccation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water. go-plus.json desiccation tolerance http://purl.obolibrary.org/obo/GO_0009269 GO:0034204 biolink:BiologicalProcess lipid translocation The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. go-plus.json intramembrane lipid transfer http://purl.obolibrary.org/obo/GO_0034204 GO:0010255 biolink:BiologicalProcess glucose mediated signaling pathway The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes. go-plus.json glucose mediated signalling http://purl.obolibrary.org/obo/GO_0010255 GO:0034205 biolink:BiologicalProcess amyloid-beta formation The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP). go-plus.json beta-amyloid polypeptide formation from amyloid precursor protein|beta-amyloid polypeptide formation from APP|beta-amyloid formation http://purl.obolibrary.org/obo/GO_0034205 GO:0010256 biolink:BiologicalProcess endomembrane system organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. go-plus.json endomembrane system organisation|endomembrane organization http://purl.obolibrary.org/obo/GO_0010256 goslim_drosophila GO:0010250 biolink:BiologicalProcess S-methylmethionine biosynthetic process The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle. go-plus.json S-methylmethionine anabolism|S-methylmethionine synthesis|S-methylmethionine biosynthesis|S-methylmethionine formation http://purl.obolibrary.org/obo/GO_0010250 GO:0010228 biolink:BiologicalProcess vegetative to reproductive phase transition of meristem The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence. go-plus.json transition from vegetative to reproductive phase|flowering|floral evocation http://purl.obolibrary.org/obo/GO_0010228 GO:0010229 biolink:BiologicalProcess inflorescence development The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0010229 GO:0010226 biolink:BiologicalProcess response to lithium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010226 GO:0010227 biolink:BiologicalProcess floral organ abscission The controlled shedding of floral organs. go-plus.json http://purl.obolibrary.org/obo/GO_0010227 GO:0009240 biolink:BiologicalProcess isopentenyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids. go-plus.json isopentenyl pyrophosphate biosynthesis|isopentenyl pyrophosphate biosynthetic process|isopentenyl diphosphate biosynthesis|isopentenyl diphosphate anabolism|isopentenyl diphosphate synthesis|isopentenyl diphosphate formation|IPP biosynthesis|IPP biosynthetic process http://purl.obolibrary.org/obo/GO_0009240 GO:0009241 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009241 GO:0010220 biolink:BiologicalProcess positive regulation of vernalization response Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures. go-plus.json up regulation of vernalization response|upregulation of vernalization response|stimulation of vernalization response|activation of vernalization response|up-regulation of vernalization response http://purl.obolibrary.org/obo/GO_0010220 GO:0009231 biolink:BiologicalProcess riboflavin biosynthetic process The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). Wikipedia:Riboflavin|MetaCyc:RIBOSYN2-PWY go-plus.json vitamin B2 biosynthetic process|vitamin B2 biosynthesis|riboflavin biosynthesis|riboflavin anabolism|riboflavin synthesis|riboflavin formation|vitamin G biosynthetic process|vitamin G biosynthesis http://purl.obolibrary.org/obo/GO_0009231 GO:0009232 biolink:BiologicalProcess riboflavin catabolic process The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). go-plus.json vitamin B2 catabolism|riboflavin catabolism|riboflavin degradation|riboflavin breakdown|vitamin B2 catabolic process|vitamin G catabolism|vitamin G catabolic process http://purl.obolibrary.org/obo/GO_0009232 GO:0010221 biolink:BiologicalProcess negative regulation of vernalization response Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures. go-plus.json downregulation of vernalization response|down regulation of vernalization response|inhibition of vernalization response|down-regulation of vernalization response http://purl.obolibrary.org/obo/GO_0010221 GO:0009233 biolink:BiologicalProcess menaquinone metabolic process The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2. go-plus.json multiprenylmenaquinone metabolism|menatetrenone metabolic process|menatetrenone metabolism|multiprenylmenaquinone metabolic process|vitamin K2 metabolic process|menaquinone metabolism|vitamin K2 metabolism http://purl.obolibrary.org/obo/GO_0009233 GO:0009234 biolink:BiologicalProcess menaquinone biosynthetic process The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2. MetaCyc:MENAQUINONESYN-PWY go-plus.json multiprenylmenaquinone biosynthetic process|multiprenylmenaquinone biosynthesis|menaquinone anabolism|menatetrenone biosynthetic process|menatetrenone biosynthesis|menaquinone synthesis|menaquinone formation|menaquinone biosynthesis|vitamin K2 biosynthetic process|vitamin K2 biosynthesis http://purl.obolibrary.org/obo/GO_0009234 GO:0009235 biolink:BiologicalProcess cobalamin metabolic process The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. go-plus.json vitamin B12 metabolism|vitamin B12 reduction|vitamin B12 metabolic process|cobalamin metabolism http://purl.obolibrary.org/obo/GO_0009235 GO:0010224 biolink:BiologicalProcess response to UV-B Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. go-plus.json response to UVB light stimulus|response to UV-B light stimulus|response to UVB radiation stimulus|response to UV-B radiation stimulus|response to medium wave ultraviolet light stimulus|response to medium wave ultraviolet radiation stimulus http://purl.obolibrary.org/obo/GO_0010224 GO:0010225 biolink:BiologicalProcess response to UV-C Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. go-plus.json response to germicidal ultraviolet radiation stimulus|response to shortwave ultraviolet light stimulus|response to UVC light stimulus|response to UV-C light stimulus|response to shortwave ultraviolet radiation stimulus|response to UVC radiation stimulus|response to UV-C radiation stimulus|response to germicidal ultraviolet light stimulus http://purl.obolibrary.org/obo/GO_0010225 GO:0009236 biolink:BiologicalProcess cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. go-plus.json cobalamin anabolism|cobalamin synthesis|cobalamin formation|cobalamin biosynthesis|vitamin B12 biosynthetic process|vitamin B12 biosynthesis http://purl.obolibrary.org/obo/GO_0009236 GO:0009237 biolink:BiologicalProcess siderophore metabolic process The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. go-plus.json siderophore metabolism|siderochrome metabolism|siderochrome metabolic process http://purl.obolibrary.org/obo/GO_0009237 GO:0010222 biolink:BiologicalProcess stem vascular tissue pattern formation Vascular tissue pattern formation as it occurs in the stem of vascular plants. go-plus.json http://purl.obolibrary.org/obo/GO_0010222 GO:0010223 biolink:BiologicalProcess secondary shoot formation The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs. go-plus.json axillary shoot system formation|axillary shoot formation|shoot branching|auxiliary shoot formation http://purl.obolibrary.org/obo/GO_0010223 GO:0009238 biolink:BiologicalProcess enterobactin metabolic process The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. go-plus.json enterochelin metabolic process|enterochelin metabolism|enterobactin metabolism http://purl.obolibrary.org/obo/GO_0009238 GO:0009239 biolink:BiologicalProcess enterobactin biosynthetic process The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. MetaCyc:ENTBACSYN-PWY go-plus.json enterobactin biosynthetic process, peptide formation|enterobactin biosynthetic process, peptide modification|enterochelin biosynthesis|enterobactin anabolism|enterochelin biosynthetic process|enterobactin synthesis|enterobactin biosynthesis|enterobactin formation|enterobactin synthetase http://purl.obolibrary.org/obo/GO_0009239 GO:0010239 biolink:BiologicalProcess chloroplast mRNA processing Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0010239 GO:0010237 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010237 GO:0010238 biolink:BiologicalProcess response to proline Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010238 GO:0009250 biolink:BiologicalProcess glucan biosynthetic process The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. go-plus.json glucan biosynthesis|glucan anabolism|glucan synthesis|glucan formation http://purl.obolibrary.org/obo/GO_0009250 GO:0009251 biolink:BiologicalProcess glucan catabolic process The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues. go-plus.json glucan degradation|glucan breakdown|glucan catabolism http://purl.obolibrary.org/obo/GO_0009251 GO:0009252 biolink:BiologicalProcess peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. go-plus.json peptidoglycan anabolism|murein biosynthesis|murein biosynthetic process|peptidoglycan synthesis|peptidoglycan formation|peptidoglycan biosynthesis http://purl.obolibrary.org/obo/GO_0009252 GO:0010231 biolink:BiologicalProcess maintenance of seed dormancy Any process that maintains a seed in a dormant state. go-plus.json http://purl.obolibrary.org/obo/GO_0010231 GO:0009242 biolink:BiologicalProcess colanic acid biosynthetic process The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide. MetaCyc:COLANSYN-PWY go-plus.json colanic acid biosynthesis|M antigen biosynthetic process|M antigen biosynthesis|colanic acid anabolism|colanic acid synthesis|colanic acid formation http://purl.obolibrary.org/obo/GO_0009242 GO:0009243 biolink:BiologicalProcess O antigen biosynthetic process The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide. go-plus.json O antigen anabolism|O antigen synthesis|O antigen biosynthesis|O antigen formation http://purl.obolibrary.org/obo/GO_0009243 GO:0010232 biolink:BiologicalProcess vascular transport The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0010232 GO:0009244 biolink:BiologicalProcess lipopolysaccharide core region biosynthetic process The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. go-plus.json lipopolysaccharide core region anabolism|lipopolysaccharide core region biosynthesis|lipopolysaccharide core region synthesis|lipopolysaccharide core region formation|LPS core region biosynthetic process http://purl.obolibrary.org/obo/GO_0009244 GO:0009245 biolink:BiologicalProcess lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. MetaCyc:NAGLIPASYN-PWY go-plus.json lipid A formation|lipid A biosynthesis|lipid A anabolism|lipid A synthesis http://purl.obolibrary.org/obo/GO_0009245 GO:0010230 biolink:BiologicalProcess alternative respiration Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa. go-plus.json http://purl.obolibrary.org/obo/GO_0010230 GO:0010235 biolink:BiologicalProcess guard mother cell cytokinesis The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells. go-plus.json guard mother cell division http://purl.obolibrary.org/obo/GO_0010235 GO:0009246 biolink:BiologicalProcess enterobacterial common antigen biosynthetic process The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria. MetaCyc:ECASYN-PWY go-plus.json enterobacterial common antigen biosynthesis|enterobacterial common antigen anabolism|enterobacterial common antigen synthesis|enterobacterial common antigen formation http://purl.obolibrary.org/obo/GO_0009246 GO:0009247 biolink:BiologicalProcess glycolipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). MetaCyc:PWY-401 go-plus.json glycolipid synthesis|glycolipid formation|glycolipid biosynthesis|glycolipid anabolism http://purl.obolibrary.org/obo/GO_0009247 GO:0010236 biolink:BiologicalProcess plastoquinone biosynthetic process The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast. MetaCyc:PWY-1581 go-plus.json plastoquinone biosynthesis|plastoquinone anabolism|plastoquinone synthesis|plastoquinone formation http://purl.obolibrary.org/obo/GO_0010236 GO:0010233 biolink:BiologicalProcess phloem transport The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0010233 GO:0009248 biolink:BiologicalProcess K antigen biosynthetic process The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens. go-plus.json K antigen biosynthesis|K antigen anabolism|K antigen synthesis|K antigen formation http://purl.obolibrary.org/obo/GO_0009248 GO:0009249 biolink:BiologicalProcess protein lipoylation The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine. go-plus.json protein-lipoic acid cofactor linkage|peptidyl-lysine lipoylation http://purl.obolibrary.org/obo/GO_0009249 GO:0010234 biolink:BiologicalProcess anther wall tapetum cell fate specification The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json tapetal cell fate specification http://purl.obolibrary.org/obo/GO_0010234 CHEBI:72405 biolink:ChemicalSubstance lysophosphatidylserine 16:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72405 chebi_ph7_3 CHEBI:1845 biolink:ChemicalSubstance 4-hydroxy-3-polyprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1845 GO:0010206 biolink:BiologicalProcess photosystem II repair Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition. go-plus.json http://purl.obolibrary.org/obo/GO_0010206 CHEBI:72408 biolink:ChemicalSubstance lysophosphatidylserine 18:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72408 chebi_ph7_3 GO:0010207 biolink:BiologicalProcess photosystem II assembly The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0010207 CHEBI:72409 biolink:ChemicalSubstance lysophosphatidylserine 18:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72409 chebi_ph7_3 GO:0010204 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010204 GO:0010205 biolink:BiologicalProcess photoinhibition The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II. Wikipedia:Photoinhibition go-plus.json photosystem II inhibition http://purl.obolibrary.org/obo/GO_0010205 GO:0010208 biolink:BiologicalProcess pollen wall assembly The formation of reticulate pollen wall pattern consisting of two layers, exine and intine. go-plus.json pollen wall formation http://purl.obolibrary.org/obo/GO_0010208 GO:0010209 biolink:MolecularActivity vacuolar sorting signal binding Binding to a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0010209 GO:0009210 biolink:BiologicalProcess pyrimidine ribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine ribonucleoside triphosphate degradation|pyrimidine ribonucleoside triphosphate catabolism|pyrimidine ribonucleoside triphosphate breakdown http://purl.obolibrary.org/obo/GO_0009210 GO:0009211 biolink:BiologicalProcess pyrimidine deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009211 GO:0009212 biolink:BiologicalProcess pyrimidine deoxyribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside triphosphate biosynthesis|pyrimidine deoxyribonucleoside triphosphate anabolism|pyrimidine deoxyribonucleoside triphosphate synthesis|pyrimidine deoxyribonucleoside triphosphate formation http://purl.obolibrary.org/obo/GO_0009212 GO:0010202 biolink:BiologicalProcess response to low fluence red light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec. go-plus.json http://purl.obolibrary.org/obo/GO_0010202 GO:0009213 biolink:BiologicalProcess pyrimidine deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside triphosphate degradation|pyrimidine deoxyribonucleoside triphosphate catabolism|pyrimidine deoxyribonucleoside triphosphate breakdown http://purl.obolibrary.org/obo/GO_0009213 GO:0010203 biolink:BiologicalProcess response to very low fluence red light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec. go-plus.json http://purl.obolibrary.org/obo/GO_0010203 GO:0009214 biolink:BiologicalProcess cyclic nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. go-plus.json cyclic nucleotide degradation|cyclic nucleotide breakdown|cyclic nucleotide catabolism http://purl.obolibrary.org/obo/GO_0009214 OBO:GOCHE_51086 biolink:OntologyClass substance with chemical role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_51086 3_STAR GO:0010200 biolink:BiologicalProcess response to chitin A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010200 GO:0009215 biolink:BiologicalProcess purine deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json purine deoxyribonucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009215 GO:0010201 biolink:BiologicalProcess response to continuous far red light stimulus by the high-irradiance response system Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence. go-plus.json http://purl.obolibrary.org/obo/GO_0010201 GO:0009216 biolink:BiologicalProcess purine deoxyribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json purine deoxyribonucleoside triphosphate anabolism|purine deoxyribonucleoside triphosphate biosynthesis|purine deoxyribonucleoside triphosphate synthesis|purine deoxyribonucleoside triphosphate formation http://purl.obolibrary.org/obo/GO_0009216 GO:0009217 biolink:BiologicalProcess purine deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json purine deoxyribonucleoside triphosphate catabolism|purine deoxyribonucleoside triphosphate degradation|purine deoxyribonucleoside triphosphate breakdown http://purl.obolibrary.org/obo/GO_0009217 GO:0009218 biolink:BiologicalProcess pyrimidine ribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine ribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009218 GO:0009219 biolink:BiologicalProcess pyrimidine deoxyribonucleotide metabolic process The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine deoxyribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009219 GO:0010217 biolink:BiologicalProcess cellular aluminum ion homeostasis Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell. go-plus.json cellular aluminium ion homeostasis http://purl.obolibrary.org/obo/GO_0010217 GO:0010218 biolink:BiologicalProcess response to far red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json response to far red light stimulus http://purl.obolibrary.org/obo/GO_0010218 GO:0010215 biolink:BiologicalProcess cellulose microfibril organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall. go-plus.json cellulose microfibril organisation http://purl.obolibrary.org/obo/GO_0010215 GO:0010216 biolink:BiologicalProcess maintenance of DNA methylation Any process involved in maintaining the methylation state of a nucleotide sequence. go-plus.json http://purl.obolibrary.org/obo/GO_0010216 GO:0010219 biolink:BiologicalProcess regulation of vernalization response Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures. go-plus.json http://purl.obolibrary.org/obo/GO_0010219 GO:0009230 biolink:BiologicalProcess thiamine catabolic process The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. go-plus.json vitamin B1 catabolism|thiamine catabolism|thiamine degradation|thiamin catabolic process|thiamine breakdown|vitamin B1 catabolic process http://purl.obolibrary.org/obo/GO_0009230 GO:0009220 biolink:BiologicalProcess pyrimidine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. MetaCyc:PWY0-162 go-plus.json pyrimidine ribonucleotide anabolism|pyrimidine ribonucleotide synthesis|pyrimidine ribonucleotide biosynthesis|pyrimidine ribonucleotide formation http://purl.obolibrary.org/obo/GO_0009220 GO:0009221 biolink:BiologicalProcess pyrimidine deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. MetaCyc:PWY0-166 go-plus.json pyrimidine deoxyribonucleotide anabolism|pyrimidine deoxyribonucleotide biosynthesis|pyrimidine deoxyribonucleotide synthesis|pyrimidine deoxyribonucleotide formation http://purl.obolibrary.org/obo/GO_0009221 GO:0010210 biolink:MolecularActivity IAA-Phe conjugate hydrolase activity Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine. go-plus.json http://purl.obolibrary.org/obo/GO_0010210 GO:0009222 biolink:BiologicalProcess pyrimidine ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine ribonucleotide degradation|pyrimidine ribonucleotide breakdown|pyrimidine ribonucleotide catabolism http://purl.obolibrary.org/obo/GO_0009222 GO:0009223 biolink:BiologicalProcess pyrimidine deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json pyrimidine deoxyribonucleotide degradation|pyrimidine deoxyribonucleotide breakdown|pyrimidine deoxyribonucleotide catabolism http://purl.obolibrary.org/obo/GO_0009223 GO:0009224 biolink:BiologicalProcess CMP biosynthetic process The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate. go-plus.json CMP biosynthesis|CMP anabolism|CMP synthesis|CMP formation http://purl.obolibrary.org/obo/GO_0009224 GO:0010213 biolink:BiologicalProcess non-photoreactive DNA repair A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated. go-plus.json light-independent DNA repair http://purl.obolibrary.org/obo/GO_0010213 GO:0010214 biolink:BiologicalProcess seed coat development The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0010214 GO:0009225 biolink:BiologicalProcess nucleotide-sugar metabolic process The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json nucleotide-sugar metabolism http://purl.obolibrary.org/obo/GO_0009225 goslim_pir GO:0010211 biolink:MolecularActivity IAA-Leu conjugate hydrolase activity Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine. MetaCyc:RXN-2982 go-plus.json http://purl.obolibrary.org/obo/GO_0010211 GO:0009226 biolink:BiologicalProcess nucleotide-sugar biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json nucleotide-sugar biosynthesis|nucleotide-sugar anabolism|nucleotide-sugar synthesis|nucleotide-sugar formation http://purl.obolibrary.org/obo/GO_0009226 GO:0009227 biolink:BiologicalProcess nucleotide-sugar catabolic process The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. go-plus.json nucleotide-sugar degradation|nucleotide-sugar breakdown|nucleotide-sugar catabolism http://purl.obolibrary.org/obo/GO_0009227 GO:0010212 biolink:BiologicalProcess response to ionizing radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. go-plus.json response to ionising radiation|response to ionizing radiation stimulus http://purl.obolibrary.org/obo/GO_0010212 GO:0009228 biolink:BiologicalProcess thiamine biosynthetic process The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. MetaCyc:THISYN-PWY go-plus.json thiamin biosynthetic process|thiamin anabolism|thiamine synthesis|thiamine formation|vitamin B1 biosynthetic process|vitamin B1 biosynthesis|thiamine biosynthesis http://purl.obolibrary.org/obo/GO_0009228 GO:0009229 biolink:BiologicalProcess thiamine diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. go-plus.json TPP biosynthetic process|TPP biosynthesis|thiamine pyrophosphate biosynthetic process|thiamine pyrophosphate biosynthesis|thiamine diphosphate biosynthesis|thiamin diphosphate biosynthetic process|thiamine diphosphate anabolism|thiamin pyrophosphate biosynthesis|thiamin pyrophosphate biosynthetic process|thiamine diphosphate synthesis|thiamine diphosphate formation http://purl.obolibrary.org/obo/GO_0009229 CHEBI:72423 biolink:ChemicalSubstance phosphatidylcholine 26:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72423 chebi_ph7_3 CHEBI:72427 biolink:ChemicalSubstance phosphatidylcholine 37:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72427 chebi_ph7_3 GO:0009200 biolink:BiologicalProcess deoxyribonucleoside triphosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json deoxyribonucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009200 GO:0009201 biolink:BiologicalProcess ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json ribonucleoside triphosphate anabolism|ribonucleoside triphosphate synthesis|ribonucleoside triphosphate formation|ribonucleoside triphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009201 GO:0009202 biolink:BiologicalProcess deoxyribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json deoxyribonucleoside triphosphate anabolism|deoxyribonucleoside triphosphate synthesis|deoxyribonucleoside triphosphate formation|deoxyribonucleoside triphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009202 GO:0009203 biolink:BiologicalProcess ribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json ribonucleoside triphosphate degradation|ribonucleoside triphosphate breakdown|ribonucleoside triphosphate catabolism http://purl.obolibrary.org/obo/GO_0009203 GO:0009204 biolink:BiologicalProcess deoxyribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json deoxyribonucleoside triphosphate catabolism|deoxyribonucleoside triphosphate degradation|deoxyribonucleoside triphosphate breakdown http://purl.obolibrary.org/obo/GO_0009204 GO:0009205 biolink:BiologicalProcess purine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json purine ribonucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009205 GO:0009206 biolink:BiologicalProcess purine ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json purine ribonucleoside triphosphate anabolism|purine ribonucleoside triphosphate synthesis|purine ribonucleoside triphosphate formation|purine ribonucleoside triphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009206 GO:0009207 biolink:BiologicalProcess purine ribonucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json purine ribonucleoside triphosphate catabolism|purine ribonucleoside triphosphate degradation|purine ribonucleoside triphosphate breakdown http://purl.obolibrary.org/obo/GO_0009207 GO:0009208 biolink:BiologicalProcess pyrimidine ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine ribonucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009208 GO:0009209 biolink:BiologicalProcess pyrimidine ribonucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine ribonucleoside triphosphate synthesis|pyrimidine ribonucleoside triphosphate formation|pyrimidine ribonucleoside triphosphate biosynthesis|pyrimidine ribonucleoside triphosphate anabolism http://purl.obolibrary.org/obo/GO_0009209 GO:0097751 biolink:BiologicalProcess spore-bearing structure formation The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores. go-plus.json sporangium formation|sporophore formation http://purl.obolibrary.org/obo/GO_0097751 GO:0097752 biolink:BiologicalProcess regulation of DNA stability Any process that modulates the stability of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0097752 GO:0097750 biolink:BiologicalProcess endosome membrane tubulation A membrane tubulation process occurring in an endosome membrane. go-plus.json endosomal membrane tubulation http://purl.obolibrary.org/obo/GO_0097750 UBERON:2002260 biolink:AnatomicalEntity premaxillary-maxillary joint Joint that articulates the premaxilla and maxilla. Premaxillary-maxillary joint is paired. go-plus.json http://purl.obolibrary.org/obo/UBERON_2002260 GO:1902898 biolink:BiologicalProcess fatty acid methyl ester metabolic process The chemical reactions and pathways involving fatty acid methyl ester. go-plus.json fatty acid methyl ester metabolism|FAME metabolic process http://purl.obolibrary.org/obo/GO_1902898 GO:1902899 biolink:BiologicalProcess fatty acid methyl ester biosynthetic process The chemical reactions and pathways resulting in the formation of fatty acid methyl ester. go-plus.json fatty acid methyl ester biosynthesis|fatty acid methyl ester anabolism|FAME biosynthetic process|fatty acid methyl ester synthesis|fatty acid methyl ester formation http://purl.obolibrary.org/obo/GO_1902899 GO:1902896 biolink:BiologicalProcess terminal web assembly The aggregation, arrangement and bonding together of a set of components to form a terminal web. go-plus.json terminal web formation http://purl.obolibrary.org/obo/GO_1902896 GO:1902897 biolink:BiologicalProcess regulation of postsynaptic density protein 95 clustering Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering. go-plus.json regulation of PSD-95 clustering|regulation of post-synaptic density protein 95 clustering|regulation of Dlg4 clustering http://purl.obolibrary.org/obo/GO_1902897 GO:1902894 biolink:BiologicalProcess negative regulation of pri-miRNA transcription by RNA polymerase II Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II. go-plus.json inhibition of pri-miRNA transcription from RNA polymerase II promoter|negative regulation of pri-miRNA transcription from RNA polymerase II promoter|down regulation of pri-miRNA transcription from RNA polymerase II promoter|downregulation of pri-miRNA transcription from RNA polymerase II promoter|down-regulation of pri-miRNA transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1902894 GO:1902895 biolink:BiologicalProcess positive regulation of pri-miRNA transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II. go-plus.json up-regulation of pri-miRNA transcription from RNA polymerase II promoter|positive regulation of pri-miRNA transcription from RNA polymerase II promoter|upregulation of pri-miRNA transcription from RNA polymerase II promoter|up regulation of pri-miRNA transcription from RNA polymerase II promoter|activation of pri-miRNA transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1902895 GO:1902892 biolink:BiologicalProcess positive regulation of root hair elongation Any process that activates or increases the frequency, rate or extent of root hair elongation. go-plus.json up-regulation of root hair elongation|activation of root hair elongation|up regulation of root hair elongation|upregulation of root hair elongation http://purl.obolibrary.org/obo/GO_1902892 GO:1902893 biolink:BiologicalProcess regulation of pri-miRNA transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II. go-plus.json regulation of pri-miRNA transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1902893 GO:0034176 biolink:BiologicalProcess negative regulation of toll-like receptor 12 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway. go-plus.json negative regulation of toll-like receptor 12 signalling pathway|negative regulation of TLR12 signaling pathway http://purl.obolibrary.org/obo/GO_0034176 GO:0034177 biolink:BiologicalProcess positive regulation of toll-like receptor 12 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway. go-plus.json positive regulation of toll-like receptor 12 signalling pathway|positive regulation of TLR12 signaling pathway http://purl.obolibrary.org/obo/GO_0034177 GO:0034178 biolink:BiologicalProcess toll-like receptor 13 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 13. go-plus.json toll-like receptor 13 signalling pathway|TLR13 signaling pathway http://purl.obolibrary.org/obo/GO_0034178 CHEBI:1883 biolink:ChemicalSubstance 4-hydroxystyrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_1883 chebi_ph7_3 GO:0034179 biolink:BiologicalProcess regulation of toll-like receptor 13 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway. go-plus.json regulation of TLR13 signaling pathway|regulation of toll-like receptor 13 signalling pathway http://purl.obolibrary.org/obo/GO_0034179 GO:0034170 biolink:BiologicalProcess toll-like receptor 11 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 11. go-plus.json TLR11 signaling pathway|toll-like receptor 11 signalling pathway http://purl.obolibrary.org/obo/GO_0034170 GO:0034171 biolink:BiologicalProcess regulation of toll-like receptor 11 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway. go-plus.json regulation of toll-like receptor 11 signalling pathway|regulation of TLR11 signaling pathway http://purl.obolibrary.org/obo/GO_0034171 GO:0034172 biolink:BiologicalProcess negative regulation of toll-like receptor 11 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway. go-plus.json negative regulation of toll-like receptor 11 signalling pathway|negative regulation of TLR11 signaling pathway http://purl.obolibrary.org/obo/GO_0034172 GO:0097755 biolink:BiologicalProcess obsolete positive regulation of blood vessel diameter OBSOLETE. Any process that increases the diameter of blood vessels. go-plus.json positive regulation of vasodilation http://purl.obolibrary.org/obo/GO_0097755 GO:0097756 biolink:BiologicalProcess obsolete negative regulation of blood vessel diameter OBSOLETE. Any process that decreases the diameter of blood vessels. go-plus.json negative regulation of vasodilation http://purl.obolibrary.org/obo/GO_0097756 GO:0034173 biolink:BiologicalProcess positive regulation of toll-like receptor 11 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway. go-plus.json positive regulation of toll-like receptor 11 signalling pathway|positive regulation of TLR11 signaling pathway http://purl.obolibrary.org/obo/GO_0034173 GO:0034174 biolink:BiologicalProcess toll-like receptor 12 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 12. go-plus.json toll-like receptor 12 signalling pathway|TLR12 signaling pathway http://purl.obolibrary.org/obo/GO_0034174 GO:0097753 biolink:BiologicalProcess membrane bending A membrane organization process resulting in the bending of a membrane. go-plus.json membrane curvature http://purl.obolibrary.org/obo/GO_0097753 GO:0097754 biolink:BiologicalProcess clathrin-mediated membrane bending A membrane bending process mediated by clathrin. go-plus.json http://purl.obolibrary.org/obo/GO_0097754 GO:0034175 biolink:BiologicalProcess regulation of toll-like receptor 12 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway. go-plus.json regulation of toll-like receptor 12 signalling pathway|regulation of TLR12 signaling pathway http://purl.obolibrary.org/obo/GO_0034175 GO:0034165 biolink:BiologicalProcess positive regulation of toll-like receptor 9 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway. go-plus.json positive regulation of toll-like receptor 9 signalling pathway|positive regulation of TLR9 signaling pathway http://purl.obolibrary.org/obo/GO_0034165 GO:0034166 biolink:BiologicalProcess toll-like receptor 10 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 10. go-plus.json TLR10 signaling pathway|toll-like receptor 10 signalling pathway http://purl.obolibrary.org/obo/GO_0034166 GO:0034167 biolink:BiologicalProcess regulation of toll-like receptor 10 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway. go-plus.json regulation of toll-like receptor 10 signalling pathway|regulation of TLR10 signaling pathway http://purl.obolibrary.org/obo/GO_0034167 GO:0034168 biolink:BiologicalProcess negative regulation of toll-like receptor 10 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway. go-plus.json negative regulation of TLR10 signaling pathway|negative regulation of toll-like receptor 10 signalling pathway http://purl.obolibrary.org/obo/GO_0034168 CHEBI:1895 biolink:ChemicalSubstance 4-methylbenzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1895 chebi_ph7_3 GO:0034169 biolink:BiologicalProcess positive regulation of toll-like receptor 10 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway. go-plus.json positive regulation of TLR10 signaling pathway|positive regulation of toll-like receptor 10 signalling pathway http://purl.obolibrary.org/obo/GO_0034169 GO:0034160 biolink:BiologicalProcess negative regulation of toll-like receptor 8 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway. go-plus.json negative regulation of TLR8 signaling pathway|negative regulation of toll-like receptor 8 signalling pathway http://purl.obolibrary.org/obo/GO_0034160 GO:0034161 biolink:BiologicalProcess positive regulation of toll-like receptor 8 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway. go-plus.json positive regulation of toll-like receptor 8 signalling pathway|positive regulation of TLR8 signaling pathway http://purl.obolibrary.org/obo/GO_0034161 GO:0034162 biolink:BiologicalProcess toll-like receptor 9 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 9. go-plus.json TLR9 signaling pathway|toll-like receptor 9 signalling pathway http://purl.obolibrary.org/obo/GO_0034162 GO:0034163 biolink:BiologicalProcess regulation of toll-like receptor 9 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway. go-plus.json regulation of toll-like receptor 9 signalling pathway|regulation of TLR9 signaling pathway http://purl.obolibrary.org/obo/GO_0034163 GO:0034164 biolink:BiologicalProcess negative regulation of toll-like receptor 9 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway. go-plus.json negative regulation of TLR9 signaling pathway|negative regulation of toll-like receptor 9 signalling pathway http://purl.obolibrary.org/obo/GO_0034164 GO:0097730 biolink:CellularComponent non-motile cilium A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors. go-plus.json nonmotile primary cilia|sensory cilium|nonmotile primary cilium|immotile cilium|immotile primary cilium|nonmotile cilium http://purl.obolibrary.org/obo/GO_0097730 OBA:VT0005404 biolink:OntologyClass axon morphology trait The morphology of a axon. go-plus.json morphology of axon http://purl.obolibrary.org/obo/OBA_VT0005404 GO:0010187 biolink:BiologicalProcess negative regulation of seed germination Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination. go-plus.json down-regulation of seed germination|downregulation of seed germination|down regulation of seed germination|inhibition of seed germination http://purl.obolibrary.org/obo/GO_0010187 GO:0034154 biolink:BiologicalProcess toll-like receptor 7 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 7. go-plus.json toll-like receptor 7 signalling pathway|TLR7 signaling pathway http://purl.obolibrary.org/obo/GO_0034154 GO:0009198 biolink:BiologicalProcess pyrimidine deoxyribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside diphosphate degradation|pyrimidine deoxyribonucleoside diphosphate catabolism|pyrimidine deoxyribonucleoside diphosphate breakdown http://purl.obolibrary.org/obo/GO_0009198 GO:0010188 biolink:BiologicalProcess response to microbial phytotoxin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants. go-plus.json http://purl.obolibrary.org/obo/GO_0010188 GO:0034155 biolink:BiologicalProcess regulation of toll-like receptor 7 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway. go-plus.json regulation of TLR7 signaling pathway|regulation of toll-like receptor 7 signalling pathway http://purl.obolibrary.org/obo/GO_0034155 GO:0009199 biolink:BiologicalProcess ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. go-plus.json ribonucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009199 GO:0010185 biolink:BiologicalProcess regulation of cellular defense response Any process that modulates the frequency, rate or extent of cellular defense response. go-plus.json regulation of cellular defence response http://purl.obolibrary.org/obo/GO_0010185 GO:0034156 biolink:BiologicalProcess negative regulation of toll-like receptor 7 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway. go-plus.json negative regulation of toll-like receptor 7 signalling pathway|negative regulation of TLR7 signaling pathway http://purl.obolibrary.org/obo/GO_0034156 GO:0010186 biolink:BiologicalProcess positive regulation of cellular defense response Any process that activates or increases the frequency, rate or extent of cellular defense response. go-plus.json positive regulation of cellular defence response|upregulation of cellular defense response|up regulation of cellular defense response|activation of cellular defense response|stimulation of cellular defense response|up-regulation of cellular defense response http://purl.obolibrary.org/obo/GO_0010186 GO:0034157 biolink:BiologicalProcess positive regulation of toll-like receptor 7 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway. go-plus.json positive regulation of TLR7 signaling pathway|positive regulation of toll-like receptor 7 signalling pathway http://purl.obolibrary.org/obo/GO_0034157 GO:0034158 biolink:BiologicalProcess toll-like receptor 8 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 8. go-plus.json toll-like receptor 8 signalling pathway|TLR8 signaling pathway http://purl.obolibrary.org/obo/GO_0034158 GO:0034159 biolink:BiologicalProcess regulation of toll-like receptor 8 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway. go-plus.json regulation of TLR8 signaling pathway|regulation of toll-like receptor 8 signalling pathway http://purl.obolibrary.org/obo/GO_0034159 GO:0010189 biolink:BiologicalProcess vitamin E biosynthetic process The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. MetaCyc:PWY-1422 go-plus.json vitamin E anabolism|vitamin E synthesis|vitamin E formation|tocopherol biosynthetic process|tocopherol biosynthesis|alpha-tocopherol biosynthesis|alpha-tocopherol biosynthetic process|vitamin E biosynthesis http://purl.obolibrary.org/obo/GO_0010189 GO:0097739 biolink:BiologicalProcess negative regulation of ferrichrome biosynthetic process in response to iron Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097739 GO:0097737 biolink:BiologicalProcess acquisition of mycelium reproductive competence A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium. go-plus.json mycelium developmental competence http://purl.obolibrary.org/obo/GO_0097737 GO:0010180 biolink:MolecularActivity thioglucosidase binding Binding to a thioglucosidase enzyme. go-plus.json myrosinase binding http://purl.obolibrary.org/obo/GO_0010180 GO:0097738 biolink:BiologicalProcess substrate mycelium formation The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0097738 GO:0097735 biolink:CellularComponent DIM/DIP cell wall layer A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0097735 GO:0097736 biolink:BiologicalProcess aerial mycelium formation The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae. go-plus.json aerial hyphal growth|fertile mycelium formation http://purl.obolibrary.org/obo/GO_0097736 GO:0097733 biolink:CellularComponent photoreceptor cell cilium A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment. go-plus.json photoreceptor cilium http://purl.obolibrary.org/obo/GO_0097733 GO:0034150 biolink:BiologicalProcess toll-like receptor 6 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 6. go-plus.json TLR6 signaling pathway|toll-like receptor 6 signalling pathway http://purl.obolibrary.org/obo/GO_0034150 GO:0010183 biolink:BiologicalProcess pollen tube guidance The process in which the growth of pollen tube is directed towards the female gametophyte. go-plus.json http://purl.obolibrary.org/obo/GO_0010183 GO:0034151 biolink:BiologicalProcess regulation of toll-like receptor 6 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway. go-plus.json regulation of TLR6 signaling pathway|regulation of toll-like receptor 6 signalling pathway http://purl.obolibrary.org/obo/GO_0034151 GO:0010184 biolink:BiologicalProcess cytokinin transport The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010184 GO:0097734 biolink:BiologicalProcess extracellular exosome biogenesis The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. go-plus.json intraluminal vesicle assembly|exosome biogenesis|ILV assembly|exosome production|exosome assembly or secretion http://purl.obolibrary.org/obo/GO_0097734 GO:0034152 biolink:BiologicalProcess negative regulation of toll-like receptor 6 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway. go-plus.json negative regulation of TLR6 signaling pathway|negative regulation of toll-like receptor 6 signalling pathway http://purl.obolibrary.org/obo/GO_0034152 GO:0010181 biolink:MolecularActivity FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json flavin mononucleotide binding http://purl.obolibrary.org/obo/GO_0010181 GO:0097731 biolink:CellularComponent 9+0 non-motile cilium A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme). go-plus.json non-motile 9+0 cilium|9+0 immotile cilium|primary cilium http://purl.obolibrary.org/obo/GO_0097731 GO:0034153 biolink:BiologicalProcess positive regulation of toll-like receptor 6 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway. go-plus.json positive regulation of TLR6 signaling pathway|positive regulation of toll-like receptor 6 signalling pathway http://purl.obolibrary.org/obo/GO_0034153 GO:0097732 biolink:CellularComponent 9+2 non-motile cilium A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). go-plus.json non-motile 9+2 cilium|9+2 immotile cilium http://purl.obolibrary.org/obo/GO_0097732 GO:0010182 biolink:BiologicalProcess sugar mediated signaling pathway The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes. go-plus.json sugar mediated signalling http://purl.obolibrary.org/obo/GO_0010182 GO:0097740 biolink:CellularComponent paraflagellar rod A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling. go-plus.json PFR http://purl.obolibrary.org/obo/GO_0097740 GO:0097741 biolink:CellularComponent mastigoneme A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum. go-plus.json http://purl.obolibrary.org/obo/GO_0097741 GO:0034143 biolink:BiologicalProcess regulation of toll-like receptor 4 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway. go-plus.json regulation of TLR4 signaling pathway|regulation of toll-like receptor 4 signalling pathway http://purl.obolibrary.org/obo/GO_0034143 GO:0010198 biolink:BiologicalProcess synergid death Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles. go-plus.json synergid degeneration|synergid cell death http://purl.obolibrary.org/obo/GO_0010198 GO:0034144 biolink:BiologicalProcess negative regulation of toll-like receptor 4 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway. go-plus.json negative regulation of toll-like receptor 4 signalling pathway|negative regulation of TLR4 signaling pathway http://purl.obolibrary.org/obo/GO_0034144 GO:0010199 biolink:BiologicalProcess organ boundary specification between lateral organs and the meristem The process in which boundaries between lateral organs and the meristem is established and maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0010199 GO:0034145 biolink:BiologicalProcess positive regulation of toll-like receptor 4 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway. go-plus.json positive regulation of toll-like receptor 4 signalling pathway|positive regulation of TLR4 signaling pathway http://purl.obolibrary.org/obo/GO_0034145 GO:0010196 biolink:BiologicalProcess nonphotochemical quenching The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. go-plus.json http://purl.obolibrary.org/obo/GO_0010196 GO:0034146 biolink:BiologicalProcess toll-like receptor 5 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 5. go-plus.json toll-like receptor 5 signalling pathway|TLR5 signaling pathway http://purl.obolibrary.org/obo/GO_0034146 GO:0010197 biolink:BiologicalProcess polar nucleus fusion The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized. go-plus.json http://purl.obolibrary.org/obo/GO_0010197 GO:0034147 biolink:BiologicalProcess regulation of toll-like receptor 5 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway. go-plus.json regulation of TLR5 signaling pathway|regulation of toll-like receptor 5 signalling pathway http://purl.obolibrary.org/obo/GO_0034147 GO:0034148 biolink:BiologicalProcess negative regulation of toll-like receptor 5 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway. go-plus.json negative regulation of toll-like receptor 5 signalling pathway|negative regulation of TLR5 signaling pathway http://purl.obolibrary.org/obo/GO_0034148 GO:0034149 biolink:BiologicalProcess positive regulation of toll-like receptor 5 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway. go-plus.json positive regulation of toll-like receptor 5 signalling pathway|positive regulation of TLR5 signaling pathway http://purl.obolibrary.org/obo/GO_0034149 GO:0097748 biolink:MolecularActivity 3'-5' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end. RHEA:57528 go-plus.json http://purl.obolibrary.org/obo/GO_0097748 GO:0010190 biolink:BiologicalProcess cytochrome b6f complex assembly Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents. go-plus.json cytochrome b6f complex biogenesis http://purl.obolibrary.org/obo/GO_0010190 GO:0010191 biolink:BiologicalProcess mucilage metabolic process The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants. go-plus.json mucilage metabolism http://purl.obolibrary.org/obo/GO_0010191 goslim_pir GO:0097749 biolink:BiologicalProcess membrane tubulation A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules). go-plus.json http://purl.obolibrary.org/obo/GO_0097749 GO:0097746 biolink:BiologicalProcess blood vessel diameter maintenance Any process that modulates the diameter of blood vessels. go-plus.json regulation of vasodilation|blood vessel diameter homeostasis|regulation of blood vessel diameter|regulation of vasodilatation|regulation of blood vessel size http://purl.obolibrary.org/obo/GO_0097746 GO:0097747 biolink:MolecularActivity RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. go-plus.json http://purl.obolibrary.org/obo/GO_0097747 GO:0097744 biolink:BiologicalProcess urate salt excretion The elimination by an organism of urate salt or uric acid. go-plus.json urate excretion http://purl.obolibrary.org/obo/GO_0097744 GO:0010194 biolink:BiologicalProcess obsolete microRNA metabolic process OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity. go-plus.json microRNA metabolic process http://purl.obolibrary.org/obo/GO_0010194 GO:0034140 biolink:BiologicalProcess negative regulation of toll-like receptor 3 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway. go-plus.json negative regulation of toll-like receptor 3 signalling pathway|negative regulation of TLR3 signaling pathway http://purl.obolibrary.org/obo/GO_0034140 GO:0010195 biolink:BiologicalProcess obsolete microRNA biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity. go-plus.json microRNA anabolism|microRNA synthesis|microRNA formation|microRNA biosynthetic process|microRNA biosynthesis|miRNA biosynthetic process|miRNA biosynthesis http://purl.obolibrary.org/obo/GO_0010195 GO:0097745 biolink:BiologicalProcess mitochondrial tRNA 5'-end processing The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0097745 GO:0034141 biolink:BiologicalProcess positive regulation of toll-like receptor 3 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway. go-plus.json positive regulation of toll-like receptor 3 signalling pathway|positive regulation of TLR3 signaling pathway http://purl.obolibrary.org/obo/GO_0034141 GO:0097742 biolink:BiologicalProcess de novo centriole assembly Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects. go-plus.json acentriolar basal body biogenesis|de novo ciliary basal body assembly|de novo basal body amplification|de novo basal body assembly|multiciliation|de novo centriole amplification|de novo basal body biogenesis|multiciliogenesis|de novo basal body generation http://purl.obolibrary.org/obo/GO_0097742 GO:0010192 biolink:BiologicalProcess mucilage biosynthetic process The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants. go-plus.json mucilage anabolism|mucilage synthesis|mucilage formation|mucilage biosynthesis http://purl.obolibrary.org/obo/GO_0010192 GO:0034142 biolink:BiologicalProcess toll-like receptor 4 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 4. go-plus.json toll-like receptor 4 signalling pathway|TLR4 signaling pathway http://purl.obolibrary.org/obo/GO_0034142 GO:0010193 biolink:BiologicalProcess response to ozone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010193 GO:0097743 biolink:BiologicalProcess de novo centriole assembly via blepharoplast A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface. go-plus.json multiciliation|multiciliogenesis http://purl.obolibrary.org/obo/GO_0097743 GO:0009180 biolink:BiologicalProcess purine ribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json purine ribonucleoside diphosphate anabolism|purine ribonucleoside diphosphate biosynthesis|purine ribonucleoside diphosphate synthesis|purine ribonucleoside diphosphate formation http://purl.obolibrary.org/obo/GO_0009180 GO:0009181 biolink:BiologicalProcess purine ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json purine ribonucleoside diphosphate degradation|purine ribonucleoside diphosphate breakdown|purine ribonucleoside diphosphate catabolism http://purl.obolibrary.org/obo/GO_0009181 GO:0009182 biolink:BiologicalProcess purine deoxyribonucleoside diphosphate metabolic process The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json purine deoxyribonucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009182 GO:0009183 biolink:BiologicalProcess purine deoxyribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json purine deoxyribonucleoside diphosphate synthesis|purine deoxyribonucleoside diphosphate formation|purine deoxyribonucleoside diphosphate biosynthesis|purine deoxyribonucleoside diphosphate anabolism http://purl.obolibrary.org/obo/GO_0009183 GO:0009184 biolink:BiologicalProcess purine deoxyribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json purine deoxyribonucleoside diphosphate catabolism|purine deoxyribonucleoside diphosphate degradation|purine deoxyribonucleoside diphosphate breakdown http://purl.obolibrary.org/obo/GO_0009184 GO:0009185 biolink:BiologicalProcess ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json ribonucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009185 GO:0009186 biolink:BiologicalProcess deoxyribonucleoside diphosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json deoxyribonucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009186 GO:0009176 biolink:BiologicalProcess pyrimidine deoxyribonucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009176 GO:0010165 biolink:BiologicalProcess response to X-ray Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). go-plus.json response to X-ray radiation stimulus http://purl.obolibrary.org/obo/GO_0010165 GO:0034132 biolink:BiologicalProcess negative regulation of toll-like receptor 1 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway. go-plus.json negative regulation of TLR1 signaling pathway|negative regulation of toll-like receptor 1 signalling pathway http://purl.obolibrary.org/obo/GO_0034132 GO:0010166 biolink:BiologicalProcess wax metabolic process The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids. go-plus.json wax metabolism http://purl.obolibrary.org/obo/GO_0010166 GO:0009177 biolink:BiologicalProcess pyrimidine deoxyribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside monophosphate biosynthesis|pyrimidine deoxyribonucleoside monophosphate anabolism|pyrimidine deoxyribonucleoside monophosphate synthesis|pyrimidine deoxyribonucleoside monophosphate formation http://purl.obolibrary.org/obo/GO_0009177 GO:0034133 biolink:BiologicalProcess positive regulation of toll-like receptor 1 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway. go-plus.json positive regulation of TLR1 signaling pathway|positive regulation of toll-like receptor 1 signalling pathway http://purl.obolibrary.org/obo/GO_0034133 GO:0034134 biolink:BiologicalProcess toll-like receptor 2 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 2. go-plus.json toll-like receptor 2 signalling pathway|TLR2 signaling pathway http://purl.obolibrary.org/obo/GO_0034134 GO:0009178 biolink:BiologicalProcess pyrimidine deoxyribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside monophosphate catabolism|pyrimidine deoxyribonucleoside monophosphate breakdown|pyrimidine deoxyribonucleoside monophosphate degradation http://purl.obolibrary.org/obo/GO_0009178 GO:0010163 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010163 GO:0010164 biolink:BiologicalProcess response to cesium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus. go-plus.json response to cesium http://purl.obolibrary.org/obo/GO_0010164 GO:0034135 biolink:BiologicalProcess regulation of toll-like receptor 2 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway. go-plus.json regulation of toll-like receptor 2 signalling pathway|regulation of TLR2 signaling pathway http://purl.obolibrary.org/obo/GO_0034135 GO:0009179 biolink:BiologicalProcess purine ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json purine ribonucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009179 GO:0010169 biolink:CellularComponent thioglucosidase complex A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds. go-plus.json myrosinase complex http://purl.obolibrary.org/obo/GO_0010169 GO:0034136 biolink:BiologicalProcess negative regulation of toll-like receptor 2 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway. go-plus.json negative regulation of TLR2 signaling pathway|negative regulation of toll-like receptor 2 signalling pathway http://purl.obolibrary.org/obo/GO_0034136 GO:0034137 biolink:BiologicalProcess positive regulation of toll-like receptor 2 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway. go-plus.json positive regulation of TLR2 signaling pathway|positive regulation of toll-like receptor 2 signalling pathway http://purl.obolibrary.org/obo/GO_0034137 GO:0010167 biolink:BiologicalProcess response to nitrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010167 GO:0034138 biolink:BiologicalProcess toll-like receptor 3 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. go-plus.json toll-like receptor 3 signalling pathway|TLR3 signaling pathway http://purl.obolibrary.org/obo/GO_0034138 GO:0010168 biolink:CellularComponent ER body A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species. go-plus.json endoplasmic reticulum body http://purl.obolibrary.org/obo/GO_0010168 GO:0034139 biolink:BiologicalProcess regulation of toll-like receptor 3 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway. go-plus.json regulation of TLR3 signaling pathway|regulation of toll-like receptor 3 signalling pathway http://purl.obolibrary.org/obo/GO_0034139 GO:0010161 biolink:BiologicalProcess red light signaling pathway The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json red light phototransduction|red light signalling pathway|red light signal transduction http://purl.obolibrary.org/obo/GO_0010161 GO:0010162 biolink:BiologicalProcess seed dormancy process A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors. Wikipedia:Seed#Seed_dormancy_and_protection go-plus.json seed dormancy http://purl.obolibrary.org/obo/GO_0010162 GO:0034130 biolink:BiologicalProcess toll-like receptor 1 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 1. go-plus.json TLR1 signaling pathway|toll-like receptor 1 signalling pathway http://purl.obolibrary.org/obo/GO_0034130 GO:0010160 biolink:BiologicalProcess formation of animal organ boundary The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. go-plus.json organ boundary specification http://purl.obolibrary.org/obo/GO_0010160 GO:0034131 biolink:BiologicalProcess regulation of toll-like receptor 1 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway. go-plus.json regulation of toll-like receptor 1 signalling pathway|regulation of TLR1 signaling pathway http://purl.obolibrary.org/obo/GO_0034131 GO:0009190 biolink:BiologicalProcess cyclic nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. go-plus.json cyclic nucleotide anabolism|cyclic nucleotide synthesis|cyclic nucleotide formation|cyclic nucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0009190 GO:0034129 biolink:BiologicalProcess positive regulation of MyD88-independent toll-like receptor signaling pathway Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway. go-plus.json positive regulation of MyD88-independent TLR signaling pathway|positive regulation of MyD88-independent toll-like receptor|positive regulation of MyD88-independent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034129 GO:0009191 biolink:BiologicalProcess ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json ribonucleoside diphosphate breakdown|ribonucleoside diphosphate catabolism|ribonucleoside diphosphate degradation http://purl.obolibrary.org/obo/GO_0009191 GO:0009192 biolink:BiologicalProcess deoxyribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json deoxyribonucleoside diphosphate catabolism|deoxyribonucleoside diphosphate degradation|deoxyribonucleoside diphosphate breakdown http://purl.obolibrary.org/obo/GO_0009192 GO:0009193 biolink:BiologicalProcess pyrimidine ribonucleoside diphosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine ribonucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009193 GO:0009194 biolink:BiologicalProcess pyrimidine ribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine ribonucleoside diphosphate anabolism|pyrimidine ribonucleoside diphosphate synthesis|pyrimidine ribonucleoside diphosphate formation|pyrimidine ribonucleoside diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009194 GO:0009195 biolink:BiologicalProcess pyrimidine ribonucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine ribonucleoside diphosphate degradation|pyrimidine ribonucleoside diphosphate catabolism|pyrimidine ribonucleoside diphosphate breakdown http://purl.obolibrary.org/obo/GO_0009195 GO:0009196 biolink:BiologicalProcess pyrimidine deoxyribonucleoside diphosphate metabolic process The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009196 GO:0009197 biolink:BiologicalProcess pyrimidine deoxyribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine deoxyribonucleoside diphosphate anabolism|pyrimidine deoxyribonucleoside diphosphate synthesis|pyrimidine deoxyribonucleoside diphosphate formation|pyrimidine deoxyribonucleoside diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009197 GO:0009187 biolink:BiologicalProcess cyclic nucleotide metabolic process The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. go-plus.json cyclic nucleotide metabolism http://purl.obolibrary.org/obo/GO_0009187 GO:0034121 biolink:BiologicalProcess regulation of toll-like receptor signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway. go-plus.json regulation of TLR signaling pathway|regulation of toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034121 GO:0010176 biolink:MolecularActivity homogentisate phytyltransferase activity Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol. MetaCyc:RXN-2541|RHEA:37975|KEGG_REACTION:R07500 go-plus.json http://purl.obolibrary.org/obo/GO_0010176 GO:0009188 biolink:BiologicalProcess ribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. go-plus.json ribonucleoside diphosphate anabolism|ribonucleoside diphosphate synthesis|ribonucleoside diphosphate formation|ribonucleoside diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009188 GO:0034122 biolink:BiologicalProcess negative regulation of toll-like receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway. go-plus.json negative regulation of TLR signaling pathway|negative regulation of toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034122 GO:0010177 biolink:MolecularActivity 2-(2'-methylthio)ethylmalate synthase activity Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+. MetaCyc:RXN-2202|EC:2.3.3.17 go-plus.json methylthioalkylmalate synthase activity http://purl.obolibrary.org/obo/GO_0010177 GO:0010174 biolink:MolecularActivity nucleoside transmembrane transporter activity, against a concentration gradient Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient. go-plus.json concentrative nucleoside transporter activity http://purl.obolibrary.org/obo/GO_0010174 GO:0034123 biolink:BiologicalProcess positive regulation of toll-like receptor signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway. go-plus.json positive regulation of TLR signaling pathway|positive regulation of toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034123 GO:0009189 biolink:BiologicalProcess deoxyribonucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json deoxyribonucleoside diphosphate anabolism|deoxyribonucleoside diphosphate synthesis|deoxyribonucleoside diphosphate biosynthesis|deoxyribonucleoside diphosphate formation http://purl.obolibrary.org/obo/GO_0009189 GO:0034124 biolink:BiologicalProcess regulation of MyD88-dependent toll-like receptor signaling pathway Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway. go-plus.json regulation ofMyD88-dependent toll-like receptor signalling pathway|regulation ofMyD88-dependent TLR signaling pathway http://purl.obolibrary.org/obo/GO_0034124 GO:0010175 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010175 GO:0034125 biolink:BiologicalProcess negative regulation of MyD88-dependent toll-like receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway. go-plus.json negative regulation of MyD88-dependent TLR signaling pathway|negative regulation of MyD88-dependent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034125 GO:0034126 biolink:BiologicalProcess positive regulation of MyD88-dependent toll-like receptor signaling pathway Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway. go-plus.json positive regulation of MyD88-dependent TLR signaling pathway|positive regulation of MyD88-dependent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034126 GO:0034127 biolink:BiologicalProcess regulation of MyD88-independent toll-like receptor signaling pathway Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway. go-plus.json regulation ofMyD88-independent TLR signaling pathway|regulation ofMyD88-independent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034127 GO:0010178 biolink:MolecularActivity IAA-amino acid conjugate hydrolase activity Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0010178 GO:0034128 biolink:BiologicalProcess negative regulation of MyD88-independent toll-like receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway. go-plus.json negative regulation of MyD88-independent TLR signaling pathway|negative regulation of MyD88-independent toll-like receptor signalling pathway http://purl.obolibrary.org/obo/GO_0034128 GO:0010179 biolink:MolecularActivity IAA-Ala conjugate hydrolase activity Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine. MetaCyc:RXN-2981 go-plus.json http://purl.obolibrary.org/obo/GO_0010179 GO:0010172 biolink:BiologicalProcess embryonic body morphogenesis The process in which the anatomical structures of the embryonic soma are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010172 GO:0010173 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010173 GO:0010170 biolink:CellularComponent glucose-1-phosphate adenylyltransferase complex Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0010170 GO:0034120 biolink:BiologicalProcess positive regulation of erythrocyte aggregation Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation. go-plus.json positive regulation of RBC aggregation|positive regulation of red blood cell aggregation http://purl.obolibrary.org/obo/GO_0034120 GO:0010171 biolink:BiologicalProcess body morphogenesis The process in which the anatomical structures of the soma are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010171 GO:0034118 biolink:BiologicalProcess regulation of erythrocyte aggregation Any process that modulates the frequency, rate, or extent of erythrocyte aggregation. go-plus.json regulation of red blood cell aggregation|regulation of RBC aggregation http://purl.obolibrary.org/obo/GO_0034118 GO:0034119 biolink:BiologicalProcess negative regulation of erythrocyte aggregation Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation. go-plus.json negative regulation of red blood cell aggregation|negative regulation of RBC aggregation http://purl.obolibrary.org/obo/GO_0034119 GO:0010149 biolink:BiologicalProcess obsolete senescence OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed. Wikipedia:Senescence go-plus.json senescence http://purl.obolibrary.org/obo/GO_0010149 GO:0009161 biolink:BiologicalProcess ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json ribonucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009161 GO:0009162 biolink:BiologicalProcess deoxyribonucleoside monophosphate metabolic process The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json deoxyribonucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009162 GO:0009163 biolink:BiologicalProcess nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json nucleoside anabolism|nucleoside synthesis|nucleoside formation|nucleoside biosynthesis http://purl.obolibrary.org/obo/GO_0009163 GO:0009164 biolink:BiologicalProcess nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json nucleoside catabolism|nucleoside degradation|nucleoside breakdown http://purl.obolibrary.org/obo/GO_0009164 GO:0034110 biolink:BiologicalProcess regulation of homotypic cell-cell adhesion Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0034110 GO:0010143 biolink:BiologicalProcess cutin biosynthetic process The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants. MetaCyc:PWY-321 go-plus.json cutin biosynthesis|cutin anabolism|cutin synthesis|cutin formation http://purl.obolibrary.org/obo/GO_0010143 GO:0009154 biolink:BiologicalProcess purine ribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine ribonucleotide catabolism|purine ribonucleotide degradation|purine ribonucleotide breakdown http://purl.obolibrary.org/obo/GO_0009154 GO:0009155 biolink:BiologicalProcess purine deoxyribonucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine deoxyribonucleotide catabolism|purine deoxyribonucleotide breakdown|purine deoxyribonucleotide degradation http://purl.obolibrary.org/obo/GO_0009155 GO:0010144 biolink:BiologicalProcess pyridoxal phosphate biosynthetic process from pyridoxamine The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine. go-plus.json pyridoxal 5'-phosphate salvage from pyridoxamine|pyridoxal phosphate anabolism from pyridoxamine|vitamin B6 biosynthesis from pyridoxamine|vitamin B6 biosynthetic process from pyridoxamine|pyridoxal phosphate synthesis from pyridoxamine|pyridoxal phosphate formation from pyridoxamine http://purl.obolibrary.org/obo/GO_0010144 GO:0034111 biolink:BiologicalProcess negative regulation of homotypic cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0034111 GO:0009156 biolink:BiologicalProcess ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json ribonucleoside monophosphate biosynthesis|ribonucleoside monophosphate anabolism|ribonucleoside monophosphate synthesis|ribonucleoside monophosphate formation http://purl.obolibrary.org/obo/GO_0009156 GO:0010141 biolink:BiologicalProcess obsolete guanine, xanthine and their nucleoside salvage OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis. go-plus.json guanine, xanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0010141 GO:0034112 biolink:BiologicalProcess positive regulation of homotypic cell-cell adhesion Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0034112 GO:0010142 biolink:BiologicalProcess farnesyl diphosphate biosynthetic process, mevalonate pathway The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols. MetaCyc:PWY-922 go-plus.json farnesyl diphosphate anabolism, mevalonate pathway|Ac-MVA pathway|farnesyl diphosphate synthesis, mevalonate pathway|farnesyl diphosphate formation, mevalonate pathway|isoprenoid pathway|acetate-mevalonate pathway http://purl.obolibrary.org/obo/GO_0010142 GO:0009157 biolink:BiologicalProcess deoxyribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json deoxyribonucleoside monophosphate anabolism|deoxyribonucleoside monophosphate synthesis|deoxyribonucleoside monophosphate formation|deoxyribonucleoside monophosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009157 GO:0034113 biolink:BiologicalProcess heterotypic cell-cell adhesion The attachment of a cell to a cell of a different type via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0034113 GO:0009158 biolink:BiologicalProcess ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json ribonucleoside monophosphate degradation|ribonucleoside monophosphate breakdown|ribonucleoside monophosphate catabolism http://purl.obolibrary.org/obo/GO_0009158 GO:0034114 biolink:BiologicalProcess regulation of heterotypic cell-cell adhesion Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0034114 GO:0010147 biolink:BiologicalProcess fructan catabolic process The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues. MetaCyc:PWY-862 go-plus.json fructan degradation|fructan breakdown|fructan catabolism|levan catabolic process|levan catabolism http://purl.obolibrary.org/obo/GO_0010147 GO:0009159 biolink:BiologicalProcess deoxyribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json deoxyribonucleoside monophosphate catabolism|deoxyribonucleoside monophosphate degradation|deoxyribonucleoside monophosphate breakdown http://purl.obolibrary.org/obo/GO_0009159 GO:0010148 biolink:BiologicalProcess transpiration Release of water by the plant into the air as water vapor mainly through leaves. Wikipedia:Transpiration go-plus.json http://purl.obolibrary.org/obo/GO_0010148 GO:0034115 biolink:BiologicalProcess negative regulation of heterotypic cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0034115 GO:0034116 biolink:BiologicalProcess positive regulation of heterotypic cell-cell adhesion Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0034116 GO:0010145 biolink:BiologicalProcess fructan metabolic process The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues. go-plus.json levan metabolic process|fructan metabolism http://purl.obolibrary.org/obo/GO_0010145 GO:0034117 biolink:BiologicalProcess erythrocyte aggregation The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules. go-plus.json RBC aggregation|red blood cell aggregation http://purl.obolibrary.org/obo/GO_0034117 GO:0010146 biolink:BiologicalProcess fructan biosynthetic process The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues. MetaCyc:PWY-822 go-plus.json fructan biosynthesis|levan biosynthetic process|levan biosynthesis|fructan anabolism|fructan synthesis|fructan formation http://purl.obolibrary.org/obo/GO_0010146 GO:0010140 biolink:BiologicalProcess obsolete adenine, hypoxanthine and their nucleoside salvage OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis. go-plus.json adenine, hypoxanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0010140 GO:0034107 biolink:BiologicalProcess negative regulation of erythrocyte clearance Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance. go-plus.json negative regulation of RBC clearance|negative regulation of red blood cell clearance|negative regulation of neocytolysis http://purl.obolibrary.org/obo/GO_0034107 GO:0034108 biolink:BiologicalProcess positive regulation of erythrocyte clearance Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance. go-plus.json positive regulation of neocytolysis|positive regulation of RBC clearance|positive regulation of red blood cell clearance http://purl.obolibrary.org/obo/GO_0034108 GO:0009170 biolink:BiologicalProcess purine deoxyribonucleoside monophosphate metabolic process The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json purine deoxyribonucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009170 GO:0034109 biolink:BiologicalProcess homotypic cell-cell adhesion The attachment of a cell to a second cell of the identical type via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0034109 GO:0009171 biolink:BiologicalProcess purine deoxyribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json purine deoxyribonucleoside monophosphate anabolism|purine deoxyribonucleoside monophosphate synthesis|purine deoxyribonucleoside monophosphate formation|purine deoxyribonucleoside monophosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009171 GO:0009172 biolink:BiologicalProcess purine deoxyribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. go-plus.json purine deoxyribonucleoside monophosphate breakdown|purine deoxyribonucleoside monophosphate catabolism|purine deoxyribonucleoside monophosphate degradation http://purl.obolibrary.org/obo/GO_0009172 GO:0009173 biolink:BiologicalProcess pyrimidine ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine ribonucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009173 GO:0009174 biolink:BiologicalProcess pyrimidine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine ribonucleoside monophosphate biosynthesis|pyrimidine ribonucleoside monophosphate anabolism|pyrimidine ribonucleoside monophosphate synthesis|pyrimidine ribonucleoside monophosphate formation http://purl.obolibrary.org/obo/GO_0009174 GO:0009175 biolink:BiologicalProcess pyrimidine ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine ribonucleoside monophosphate catabolism|pyrimidine ribonucleoside monophosphate degradation|pyrimidine ribonucleoside monophosphate breakdown http://purl.obolibrary.org/obo/GO_0009175 GO:0009165 biolink:BiologicalProcess nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). go-plus.json nucleotide anabolism|nucleotide synthesis|nucleotide formation|nucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0009165 GO:0010154 biolink:BiologicalProcess fruit development The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant. go-plus.json http://purl.obolibrary.org/obo/GO_0010154 GO:0010155 biolink:BiologicalProcess regulation of proton transport Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010155 GO:0009166 biolink:BiologicalProcess nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). go-plus.json nucleotide catabolism|nucleotide degradation|nucleotide breakdown http://purl.obolibrary.org/obo/GO_0009166 GO:0034100 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034100 GO:0010152 biolink:BiologicalProcess pollen maturation The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains. go-plus.json http://purl.obolibrary.org/obo/GO_0010152 GO:0034101 biolink:BiologicalProcess erythrocyte homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. go-plus.json red blood cell homeostasis|RBC homeostasis http://purl.obolibrary.org/obo/GO_0034101 GO:0009167 biolink:BiologicalProcess purine ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json purine ribonucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009167 GO:0010153 biolink:BiologicalProcess obsolete polar cell elongation OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion. go-plus.json polarity-dependent cell elongation|polar cell elongation http://purl.obolibrary.org/obo/GO_0010153 GO:0034102 biolink:BiologicalProcess erythrocyte clearance The selective elimination of erythrocytes from the body by autoregulatory mechanisms. go-plus.json red blood cell clearance|RBC clearance|neocytolysis http://purl.obolibrary.org/obo/GO_0034102 GO:0009168 biolink:BiologicalProcess purine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json purine ribonucleoside monophosphate anabolism|purine ribonucleoside monophosphate synthesis|purine ribonucleoside monophosphate biosynthesis|purine ribonucleoside monophosphate formation http://purl.obolibrary.org/obo/GO_0009168 GO:0034103 biolink:BiologicalProcess regulation of tissue remodeling Any process that modulates the frequency, rate, or extent of tissue remodeling. go-plus.json http://purl.obolibrary.org/obo/GO_0034103 GO:0009169 biolink:BiologicalProcess purine ribonucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. go-plus.json purine ribonucleoside monophosphate degradation|purine ribonucleoside monophosphate breakdown|purine ribonucleoside monophosphate catabolism http://purl.obolibrary.org/obo/GO_0009169 GO:0010158 biolink:BiologicalProcess abaxial cell fate specification The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0010158 GO:0034104 biolink:BiologicalProcess negative regulation of tissue remodeling Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. go-plus.json http://purl.obolibrary.org/obo/GO_0034104 GO:0010159 biolink:BiologicalProcess specification of animal organ position The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ. go-plus.json http://purl.obolibrary.org/obo/GO_0010159 GO:0034105 biolink:BiologicalProcess positive regulation of tissue remodeling Any process that activates or increases the frequency, rate, or extent of tissue remodeling. go-plus.json http://purl.obolibrary.org/obo/GO_0034105 GO:0010156 biolink:BiologicalProcess obsolete sporocyte morphogenesis OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores. go-plus.json sporocyte morphogenesis http://purl.obolibrary.org/obo/GO_0010156 GO:0034106 biolink:BiologicalProcess regulation of erythrocyte clearance Any process that modulates the frequency, rate, or extent of erythrocyte clearance. go-plus.json regulation of red blood cell clearance|regulation of neocytolysis|regulation of RBC clearance http://purl.obolibrary.org/obo/GO_0034106 GO:0010157 biolink:BiologicalProcess response to chlorate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010157 GO:0010150 biolink:BiologicalProcess leaf senescence The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0010150 GO:0010151 biolink:BiologicalProcess chloroplast elongation Expansion of the chloroplast that usually precedes division. go-plus.json http://purl.obolibrary.org/obo/GO_0010151 GO:0048740 biolink:BiologicalProcess obsolete striated muscle fiber development OBSOLETE. The process whose specific outcome is the amplification and progression of myoblasts (muscle precursor cells) into terminally differentiated multinucleated muscle fibers. go-plus.json myogenesis|striated muscle fibre development|striated muscle fiber development http://purl.obolibrary.org/obo/GO_0048740 GO:1902818 biolink:BiologicalProcess ethyl acetate metabolic process The chemical reactions and pathways involving ethyl acetate. go-plus.json ethyl ethanoate metabolic process|ethyl acetate metabolism http://purl.obolibrary.org/obo/GO_1902818 GO:1902819 biolink:BiologicalProcess ethyl acetate biosynthetic process The chemical reactions and pathways resulting in the formation of ethyl acetate. go-plus.json ethyl ethanoate biosynthetic process|ethyl acetate anabolism|ethyl acetate synthesis|ethyl acetate biosynthesis|ethyl acetate formation http://purl.obolibrary.org/obo/GO_1902819 GO:0048741 biolink:BiologicalProcess skeletal muscle fiber development The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. go-plus.json skeletal muscle fibre development|skeletal myofibre development|skeletal myofiber development http://purl.obolibrary.org/obo/GO_0048741 GO:0048742 biolink:BiologicalProcess regulation of skeletal muscle fiber development Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. go-plus.json regulation of skeletal myofibre development|regulation of skeletal myofiber development|regulation of skeletal muscle fibre development http://purl.obolibrary.org/obo/GO_0048742 GO:1902816 biolink:BiologicalProcess regulation of protein localization to microtubule Any process that modulates the frequency, rate or extent of protein localization to microtubule. go-plus.json regulation of protein localisation to microtubule http://purl.obolibrary.org/obo/GO_1902816 GO:1902817 biolink:BiologicalProcess negative regulation of protein localization to microtubule Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. go-plus.json inhibition of protein localisation to microtubule|down regulation of protein localization to microtubule|downregulation of protein localization to microtubule|down regulation of protein localisation to microtubule|downregulation of protein localisation to microtubule|down-regulation of protein localization to microtubule|inhibition of protein localization to microtubule|down-regulation of protein localisation to microtubule|negative regulation of protein localisation to microtubule http://purl.obolibrary.org/obo/GO_1902817 GO:0048743 biolink:BiologicalProcess positive regulation of skeletal muscle fiber development Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. go-plus.json up regulation of skeletal muscle fiber development|activation of skeletal muscle fiber development|stimulation of skeletal muscle fiber development|up-regulation of skeletal muscle fiber development|positive regulation of skeletal myofibre development|upregulation of skeletal muscle fiber development|positive regulation of skeletal myofiber development|positive regulation of skeletal muscle fibre development http://purl.obolibrary.org/obo/GO_0048743 GO:1902814 biolink:BiologicalProcess positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry. go-plus.json activation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|positive regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry http://purl.obolibrary.org/obo/GO_1902814 GO:0048744 biolink:BiologicalProcess negative regulation of skeletal muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. go-plus.json negative regulation of skeletal muscle fibre development|down-regulation of skeletal muscle fiber development|inhibition of skeletal muscle fiber development|negative regulation of skeletal myofibre development|down regulation of skeletal muscle fiber development|negative regulation of skeletal myofiber development|downregulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0048744 CHEBI:23436 biolink:ChemicalSubstance cyanogenic glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_23436 CHEBI:23437 biolink:ChemicalSubstance cyanohydrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23437 chebi_ph7_3 GO:1902815 biolink:BiologicalProcess N,N'-diacetylchitobiose import The directed movement of N,N'-diacetylchitobiose into a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_1902815 GO:0048745 biolink:BiologicalProcess smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048745 GO:1902812 biolink:BiologicalProcess regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry. go-plus.json regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination http://purl.obolibrary.org/obo/GO_1902812 GO:0048746 biolink:BiologicalProcess obsolete smooth muscle fiber development OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure. go-plus.json smooth muscle fibre development|smooth muscle fiber development http://purl.obolibrary.org/obo/GO_0048746 GO:1902813 biolink:BiologicalProcess negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry. go-plus.json inhibition of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|negative regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|down-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|negative regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|down-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry http://purl.obolibrary.org/obo/GO_1902813 GO:0048747 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048747 GO:1902810 biolink:BiologicalProcess negative regulation of skeletal muscle fiber differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. go-plus.json inhibition of skeletal muscle fiber differentiation|down regulation of skeletal muscle fiber differentiation|downregulation of skeletal muscle fiber differentiation|down-regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_1902810 GO:1902811 biolink:BiologicalProcess positive regulation of skeletal muscle fiber differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. go-plus.json up-regulation of skeletal muscle fiber differentiation|upregulation of skeletal muscle fiber differentiation|up regulation of skeletal muscle fiber differentiation|activation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_1902811 UBERON:0000060 biolink:AnatomicalEntity anatomical wall Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. go-plus.json wall|wall of organ|organ wall http://purl.obolibrary.org/obo/UBERON_0000060 UBERON:0000061 biolink:AnatomicalEntity anatomical structure Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. go-plus.json connected biological structure|biological structure http://purl.obolibrary.org/obo/UBERON_0000061 UBERON:0000062 biolink:AnatomicalEntity organ Anatomical structure that performs a specific function or group of functions [WP]. go-plus.json body organ|anatomical unit|element http://purl.obolibrary.org/obo/UBERON_0000062 UBERON:0000063 biolink:AnatomicalEntity organ subunit A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. go-plus.json segment of organ|organ region with fixed fiat boundary|organ segment http://purl.obolibrary.org/obo/UBERON_0000063 GO:0048748 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048748 UBERON:0000068 biolink:AnatomicalEntity embryo stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. go-plus.json embryonic stage|embryogenesis http://purl.obolibrary.org/obo/UBERON_0000068 UBERON:0000069 biolink:AnatomicalEntity larval stage A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. go-plus.json trochophore stage|zoea stage|naiad, nymph|caterpillar|naiad, nymph stage|wriggler|caterpillar stage|bipinnaria|nauplius|wriggler stage|veliger|metacestode|nauplius stage|bipinnaria stage|veliger stage|larva stage|planula|tornaria|planula stage|larva|ammocoete|ammocoete stage|nymph|maggot|nymph stage|grub|maggot stage|glochidium|grub stage|glochidium stage|leptocephalus|leptocephalus stage|zoea|trochophore http://purl.obolibrary.org/obo/UBERON_0000069 GO:0048749 biolink:BiologicalProcess compound eye development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. go-plus.json insect-type retina development http://purl.obolibrary.org/obo/GO_0048749 UBERON:0000064 biolink:AnatomicalEntity organ part A multicellular structure that is a part of an organ. go-plus.json regional part of organ|cardinal organ part http://purl.obolibrary.org/obo/UBERON_0000064 UBERON:0000065 biolink:AnatomicalEntity respiratory tract Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts go-plus.json http://purl.obolibrary.org/obo/UBERON_0000065 UBERON:0000066 biolink:AnatomicalEntity fully formed stage The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. go-plus.json adult stage|fully formed animal stage|juvenile-adult stage http://purl.obolibrary.org/obo/UBERON_0000066 CHEBI:23443 biolink:ChemicalSubstance cyclic amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23443 GO:1902829 biolink:BiologicalProcess regulation of spinal cord association neuron differentiation Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation. go-plus.json regulation of spinal cord dorsal interneuron differentiation http://purl.obolibrary.org/obo/GO_1902829 GO:0048751 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048751 GO:0048752 biolink:BiologicalProcess semicircular canal morphogenesis The process in which the anatomical structures of the semicircular canals are generated and organized. go-plus.json embryonic semicircular canal morphogenesis http://purl.obolibrary.org/obo/GO_0048752 GO:1902827 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902827 GO:0048753 biolink:BiologicalProcess pigment granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. go-plus.json pigment granule organization and biogenesis|pigment granule organisation http://purl.obolibrary.org/obo/GO_0048753 goslim_pir GO:1902828 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902828 GO:0048754 biolink:BiologicalProcess branching morphogenesis of an epithelial tube The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. go-plus.json tubulogenesis http://purl.obolibrary.org/obo/GO_0048754 GO:1902825 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902825 GO:0048755 biolink:BiologicalProcess branching morphogenesis of a nerve The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). go-plus.json http://purl.obolibrary.org/obo/GO_0048755 CHEBI:23447 biolink:ChemicalSubstance cyclic nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23447 GO:1902826 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902826 GO:0048756 biolink:BiologicalProcess sieve cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. go-plus.json http://purl.obolibrary.org/obo/GO_0048756 CHEBI:23448 biolink:ChemicalSubstance cyclic oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23448 GO:1902823 biolink:BiologicalProcess negative regulation of late endosome to lysosome transport Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport. go-plus.json down-regulation of late endosome to lysosome transport|inhibition of late endosome to lysosome transport|down regulation of late endosome to lysosome transport|downregulation of late endosome to lysosome transport http://purl.obolibrary.org/obo/GO_1902823 GO:0048757 biolink:BiologicalProcess pigment granule maturation Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0048757 CHEBI:23445 biolink:ChemicalSubstance cyclic hydroxamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23445 GO:0048758 biolink:BiologicalProcess companion cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member. go-plus.json http://purl.obolibrary.org/obo/GO_0048758 GO:1902824 biolink:BiologicalProcess positive regulation of late endosome to lysosome transport Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport. go-plus.json up regulation of late endosome to lysosome transport|activation of late endosome to lysosome transport|up-regulation of late endosome to lysosome transport|upregulation of late endosome to lysosome transport http://purl.obolibrary.org/obo/GO_1902824 CHEBI:23446 biolink:ChemicalSubstance cyclic monoterpene ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23446 GO:1902821 biolink:BiologicalProcess 1-undecene biosynthetic process The chemical reactions and pathways resulting in the formation of 1-undecene. go-plus.json 1-undecene anabolism|1-undecene synthesis|1-undecene formation|1-undecene biosynthesis http://purl.obolibrary.org/obo/GO_1902821 GO:1902822 biolink:BiologicalProcess regulation of late endosome to lysosome transport Any process that modulates the frequency, rate or extent of late endosome to lysosome transport. go-plus.json regulation of prevacuolar compartment to lysosome transport http://purl.obolibrary.org/obo/GO_1902822 UBERON:0014699 biolink:AnatomicalEntity extraembryonic venous system A venous system that overlaps a umbilical cord and is part of a entire extraembryonic component. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014699 GO:1902820 biolink:BiologicalProcess 1-undecene metabolic process The chemical reactions and pathways involving 1-undecene. go-plus.json 1-undecene metabolism http://purl.obolibrary.org/obo/GO_1902820 UBERON:0014695 biolink:AnatomicalEntity deep auricular artery The deep auricular artery often arises in common with the anterior tympanic artery. It ascends in the substance of the parotid gland, behind the temporomandibular articulation, pierces the cartilaginous or bony wall of the external acoustic meatus, and supplies its cuticular lining and the outer surface of the tympanic membrane. It gives a branch to the temporomandibular joint. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014695 GO:0048750 biolink:BiologicalProcess compound eye corneal lens morphogenesis The process in which the anatomical structures of the compound eye corneal lens are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048750 OBO:GOCHE_26013 biolink:OntologyClass substance with pheromone role go-plus.json http://purl.obolibrary.org/obo/GOCHE_26013 3_STAR GO:0048759 biolink:BiologicalProcess xylem vessel member cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened. go-plus.json vessel member cell differentiation|vessel element cell differentiation http://purl.obolibrary.org/obo/GO_0048759 UBERON:0000057 biolink:AnatomicalEntity urethra the fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening go-plus.json http://purl.obolibrary.org/obo/UBERON_0000057 UBERON:0000058 biolink:AnatomicalEntity duct A tubular structure that transports secreted or excreted substances. go-plus.json exocrine gland duct|anatomical duct|exocrine duct|ducts http://purl.obolibrary.org/obo/UBERON_0000058 UBERON:0000059 biolink:AnatomicalEntity large intestine A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]. go-plus.json intestinum crassum http://purl.obolibrary.org/obo/UBERON_0000059 CHEBI:23449 biolink:ChemicalSubstance cyclic peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23449 UBERON:0024045 biolink:AnatomicalEntity white matter of the cerebellar cortex White matter that lies deep to the granular cell layer of the cerebellar cortex. It contains afferents to the cerebellar cortex and axons that run between the cerebellar cortex and the deep cerebellar nuclei. go-plus.json white matter of the cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0024045 UBERON:0000055 biolink:AnatomicalEntity vessel A tubular structure that contains, conveys body fluid, such as blood or lymph. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000055 UBERON:0000056 biolink:AnatomicalEntity ureter Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. go-plus.json metanephric duct http://purl.obolibrary.org/obo/UBERON_0000056 GO:0048762 biolink:BiologicalProcess mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. go-plus.json http://purl.obolibrary.org/obo/GO_0048762 CHEBI:23410 biolink:ChemicalSubstance cumate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23410 GO:0048763 biolink:MolecularActivity calcium-induced calcium release activity Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration. go-plus.json http://purl.obolibrary.org/obo/GO_0048763 GO:1902838 biolink:BiologicalProcess regulation of nuclear migration along microtubule Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. go-plus.json regulation of nucleus migration|regulation of nuclear migration, microtubule-mediated|regulation of transport of nucleus by microtubules|regulation of microtubule cytoskeleton-dependent nucleus positioning|regulation of microtubule-dependent nucleus positioning|regulation of transport of nucleus, microtubule-mediated|regulation of microtubule-mediated nuclear migration|regulation of microtubule cytoskeleton-dependent nuclear positioning|regulation of nuclear movement, microtubule-mediated|regulation of microtubule-dependent nuclear positioning http://purl.obolibrary.org/obo/GO_1902838 GO:0048764 biolink:BiologicalProcess trichoblast maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0048764 GO:0048765 biolink:BiologicalProcess root hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a root hair cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048765 GO:1902839 biolink:BiologicalProcess negative regulation of nuclear migration along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. go-plus.json down-regulation of microtubule-dependent nuclear positioning|negative regulation of microtubule-dependent nuclear positioning|down-regulation of nuclear migration along microtubule|down regulation of nuclear migration, microtubule-mediated|downregulation of transport of nucleus by microtubules|downregulation of microtubule cytoskeleton-dependent nucleus positioning|negative regulation of transport of nucleus, microtubule-mediated|downregulation of nuclear migration, microtubule-mediated|inhibition of microtubule-dependent nuclear positioning|down-regulation of transport of nucleus, microtubule-mediated|inhibition of nuclear migration along microtubule|down regulation of microtubule-dependent nucleus positioning|down regulation of transport of nucleus by microtubules|negative regulation of microtubule-mediated nuclear migration|down-regulation of microtubule-mediated nuclear migration|negative regulation of microtubule cytoskeleton-dependent nuclear positioning|down regulation of microtubule cytoskeleton-dependent nucleus positioning|inhibition of transport of nucleus by microtubules|down-regulation of microtubule cytoskeleton-dependent nuclear positioning|inhibition of microtubule cytoskeleton-dependent nucleus positioning|downregulation of microtubule-dependent nucleus positioning|negative regulation of nuclear migration, microtubule-mediated|downregulation of transport of nucleus, microtubule-mediated|down-regulation of nuclear migration, microtubule-mediated|downregulation of microtubule-mediated nuclear migration|downregulation of microtubule cytoskeleton-dependent nuclear positioning|down regulation of microtubule-dependent nuclear positioning|down-regulation of microtubule-dependent nucleus positioning|down regulation of nuclear migration along microtubule|negative regulation of microtubule-dependent nucleus positioning|down regulation of transport of nucleus, microtubule-mediated|inhibition of transport of nucleus, microtubule-mediated|down regulation of microtubule-mediated nuclear migration|inhibition of microtubule-mediated nuclear migration|inhibition of nuclear migration, microtubule-mediated|down regulation of microtubule cytoskeleton-dependent nuclear positioning|inhibition of microtubule cytoskeleton-dependent nuclear positioning|downregulation of nuclear migration along microtubule|downregulation of microtubule-dependent nuclear positioning|inhibition of microtubule-dependent nucleus positioning|down-regulation of transport of nucleus by microtubules|negative regulation of transport of nucleus by microtubules|negative regulation of microtubule cytoskeleton-dependent nucleus positioning|down-regulation of microtubule cytoskeleton-dependent nucleus positioning http://purl.obolibrary.org/obo/GO_1902839 UBERON:0000039 biolink:AnatomicalEntity follicular antrum Region of ovarian follicle filled with follicular fluid. go-plus.json ovarian follicle antrum|antral cavity|antrum folliculare|antrum follicularum http://purl.obolibrary.org/obo/UBERON_0000039 GO:1902836 biolink:BiologicalProcess positive regulation of proline import across plasma membrane Any process that activates or increases the frequency, rate or extent of proline import into cell. go-plus.json up regulation of proline import into cell|upregulation of proline import into cell|positive regulation of proline import into cell|up-regulation of proline import into cell|activation of proline import into cell http://purl.obolibrary.org/obo/GO_1902836 GO:0048766 biolink:BiologicalProcess root hair initiation The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth. go-plus.json http://purl.obolibrary.org/obo/GO_0048766 GO:0048767 biolink:BiologicalProcess root hair elongation The process in which the root hair grows longer. go-plus.json http://purl.obolibrary.org/obo/GO_0048767 GO:1902837 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902837 GO:1902834 biolink:BiologicalProcess regulation of proline import across plasma membrane Any process that modulates the frequency, rate or extent of proline import into cell. go-plus.json regulation of proline import into cell http://purl.obolibrary.org/obo/GO_1902834 CHEBI:23412 biolink:ChemicalSubstance cumic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23412 GO:0048768 biolink:BiologicalProcess root hair cell tip growth Localized growth of a plant root hair tip by extension of the cell wall. go-plus.json root hair tip growth http://purl.obolibrary.org/obo/GO_0048768 GO:1902835 biolink:BiologicalProcess negative regulation of proline import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell. go-plus.json down-regulation of proline import into cell|downregulation of proline import into cell|down regulation of proline import into cell|inhibition of proline import into cell|negative regulation of proline import into cell http://purl.obolibrary.org/obo/GO_1902835 GO:0048769 biolink:BiologicalProcess sarcomerogenesis The process in which sarcomeres are added in series within a fiber. go-plus.json myofibril production http://purl.obolibrary.org/obo/GO_0048769 GO:1902832 biolink:BiologicalProcess negative regulation of cell proliferation in dorsal spinal cord Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord. go-plus.json down regulation of cell proliferation in dorsal spinal cord|inhibition of cell proliferation in dorsal spinal cord|down-regulation of cell proliferation in dorsal spinal cord|downregulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_1902832 UBERON:0014687 biolink:AnatomicalEntity temporal sulcus Any of three grooves in the temporal lobe including the inferior, middle, and superior temporal sulci. go-plus.json temporal lobe sulci|temporal lobe sulcus http://purl.obolibrary.org/obo/UBERON_0014687 GO:1902833 biolink:BiologicalProcess positive regulation of cell proliferation in dorsal spinal cord Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord. go-plus.json upregulation of cell proliferation in dorsal spinal cord|up-regulation of cell proliferation in dorsal spinal cord|activation of cell proliferation in dorsal spinal cord|up regulation of cell proliferation in dorsal spinal cord http://purl.obolibrary.org/obo/GO_1902833 GO:1902830 biolink:BiologicalProcess negative regulation of spinal cord association neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation. go-plus.json down-regulation of spinal cord association neuron differentiation|downregulation of spinal cord association neuron differentiation|down-regulation of spinal cord dorsal interneuron differentiation|negative regulation of spinal cord dorsal interneuron differentiation|down regulation of spinal cord association neuron differentiation|inhibition of spinal cord association neuron differentiation|downregulation of spinal cord dorsal interneuron differentiation|down regulation of spinal cord dorsal interneuron differentiation|inhibition of spinal cord dorsal interneuron differentiation http://purl.obolibrary.org/obo/GO_1902830 GO:1902831 biolink:BiologicalProcess positive regulation of spinal cord association neuron differentiation Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation. go-plus.json up-regulation of spinal cord dorsal interneuron differentiation|activation of spinal cord dorsal interneuron differentiation|up regulation of spinal cord association neuron differentiation|positive regulation of spinal cord dorsal interneuron differentiation|upregulation of spinal cord association neuron differentiation|up regulation of spinal cord dorsal interneuron differentiation|up-regulation of spinal cord association neuron differentiation|activation of spinal cord association neuron differentiation|upregulation of spinal cord dorsal interneuron differentiation http://purl.obolibrary.org/obo/GO_1902831 GO:0048760 biolink:BiologicalProcess plant parenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure. go-plus.json parenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0048760 UBERON:0014686 biolink:AnatomicalEntity angular vein The angular vein formed by the junction of the frontal vein and supraorbital vein, runs obliquely downward, on the side of the root of the nose, to the level of the lower margin of the orbit, where it becomes the anterior facial vein. It receives the external nasal veins of the ala nasi, and communicates with the superior ophthalmic vein through the nasofrontal vein, thus establishing an important anastomosis between the anterior facial vein and the cavernous sinus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014686 GO:0048761 biolink:BiologicalProcess collenchyma cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles. go-plus.json http://purl.obolibrary.org/obo/GO_0048761 UBERON:0000047 biolink:AnatomicalEntity simple eye An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000047 CHEBI:23417 biolink:ChemicalSubstance cutins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23417 UBERON:0000042 biolink:AnatomicalEntity serous membrane multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. go-plus.json wall of serous sac|tunica serosa|serosa http://purl.obolibrary.org/obo/UBERON_0000042 UBERON:0000043 biolink:AnatomicalEntity tendon Dense regular connective tissue that connects muscle to bone[VSAO]. go-plus.json sinew|tendo http://purl.obolibrary.org/obo/UBERON_0000043 UBERON:0000044 biolink:AnatomicalEntity dorsal root ganglion Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain. (MSH) * ganglion found on the posterior root of each spinal nerve, composed of the unipolar nerve cell bodies of the sensory neurons of the nerve. (CSP) go-plus.json DRG|ganglion of dorsal root|ganglion sensorium nervi spinalis|ganglion spinalis|posterior root ganglion|spinal ganglion part of peripheral nervous system|dorsal root ganglion|ganglion spinale|spinal ganglion|dorsal root ganglia http://purl.obolibrary.org/obo/UBERON_0000044 UBERON:0000045 biolink:AnatomicalEntity ganglion A biological tissue mass, most commonly a mass of nerve cell bodies. go-plus.json ganglia|neural ganglion http://purl.obolibrary.org/obo/UBERON_0000045 GO:0048773 biolink:BiologicalProcess erythrophore differentiation The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance. go-plus.json erythrophore cell differentiation http://purl.obolibrary.org/obo/GO_0048773 GO:0048774 biolink:BiologicalProcess cyanophore differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes. go-plus.json cyanophore cell differentiation http://purl.obolibrary.org/obo/GO_0048774 GO:1902849 biolink:BiologicalProcess positive regulation of neuronal signal transduction Any process that activates or increases the frequency, rate or extent of neuronal signal transduction. go-plus.json up regulation of neuronal signal transduction|upregulation of neuronal signal transduction|up-regulation of neuronal signal transduction|activation of neuronal signal transduction http://purl.obolibrary.org/obo/GO_1902849 GO:0048775 biolink:BiologicalProcess regulation of leucophore differentiation Any process that modulates the frequency, rate or extent of leucophore differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0048775 GO:0048776 biolink:BiologicalProcess negative regulation of leucophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation. go-plus.json down-regulation of leucophore differentiation|downregulation of leucophore differentiation|down regulation of leucophore differentiation|inhibition of leucophore differentiation http://purl.obolibrary.org/obo/GO_0048776 GO:1902847 biolink:BiologicalProcess regulation of neuronal signal transduction Any process that modulates the frequency, rate or extent of neuronal signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_1902847 GO:0048777 biolink:BiologicalProcess positive regulation of leucophore differentiation Any process that activates or increases the frequency, rate or extent of leucophore differentiation. go-plus.json stimulation of leucophore differentiation|up-regulation of leucophore differentiation|activation of leucophore differentiation|up regulation of leucophore differentiation|upregulation of leucophore differentiation http://purl.obolibrary.org/obo/GO_0048777 GO:1902848 biolink:BiologicalProcess negative regulation of neuronal signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction. go-plus.json down-regulation of neuronal signal transduction|downregulation of neuronal signal transduction|down regulation of neuronal signal transduction|inhibition of neuronal signal transduction http://purl.obolibrary.org/obo/GO_1902848 GO:0048778 biolink:BiologicalProcess regulation of erythrophore differentiation Any process that modulates the frequency, rate or extent of erythrophore differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0048778 UBERON:0000029 biolink:AnatomicalEntity lymph node Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph. go-plus.json lymph gland|nodus lymphaticus http://purl.obolibrary.org/obo/UBERON_0000029 GO:1902845 biolink:BiologicalProcess negative regulation of mitotic spindle elongation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation. go-plus.json down regulation of mitotic spindle elongation|inhibition of mitotic spindle elongation|down-regulation of spindle elongation during mitosis|negative regulation of spindle elongation during mitosis|inhibition of spindle elongation during mitosis|down-regulation of mitotic spindle elongation|down regulation of spindle elongation during mitosis|downregulation of spindle elongation during mitosis|downregulation of mitotic spindle elongation http://purl.obolibrary.org/obo/GO_1902845 GO:0048779 biolink:BiologicalProcess negative regulation of erythrophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation. go-plus.json down-regulation of erythrophore differentiation|downregulation of erythrophore differentiation|down regulation of erythrophore differentiation|inhibition of erythrophore differentiation http://purl.obolibrary.org/obo/GO_0048779 CHEBI:23423 biolink:ChemicalSubstance pseudohalogen oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23423 GO:1902846 biolink:BiologicalProcess positive regulation of mitotic spindle elongation Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation. go-plus.json activation of spindle elongation during mitosis|positive regulation of spindle elongation during mitosis|upregulation of mitotic spindle elongation|up-regulation of spindle elongation during mitosis|activation of mitotic spindle elongation|up-regulation of mitotic spindle elongation|upregulation of spindle elongation during mitosis|up regulation of mitotic spindle elongation|up regulation of spindle elongation during mitosis http://purl.obolibrary.org/obo/GO_1902846 CHEBI:23424 biolink:ChemicalSubstance cyanides go-plus.json http://purl.obolibrary.org/obo/CHEBI_23424 GO:1902843 biolink:BiologicalProcess positive regulation of netrin-activated signaling pathway Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway. go-plus.json up regulation of netrin-activated signalling pathway|activation of netrin-activated signalling pathway|positive regulation of netrin-activated signalling pathway|upregulation of netrin-activated signaling pathway|up regulation of netrin-mediated signaling pathway|upregulation of netrin signaling pathway|activation of netrin-mediated signaling pathway|upregulation of netrin-activated signal transduction pathway|positive regulation of netrin-mediated signaling pathway|up-regulation of netrin-activated signaling pathway|activation of netrin-activated signaling pathway|up-regulation of netrin-activated signalling pathway|up-regulation of netrin-activated signal transduction pathway|up-regulation of netrin signaling pathway|activation of netrin-activated signal transduction pathway|activation of netrin signaling pathway|up-regulation of netrin-mediated signaling pathway|upregulation of netrin-activated signalling pathway|up regulation of netrin-activated signaling pathway|positive regulation of netrin-activated signal transduction pathway|positive regulation of netrin signaling pathway|upregulation of netrin-mediated signaling pathway|up regulation of netrin-activated signal transduction pathway|up regulation of netrin signaling pathway http://purl.obolibrary.org/obo/GO_1902843 GO:1902844 biolink:BiologicalProcess positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation. go-plus.json upregulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|positive regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|up-regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|upregulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up-regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway http://purl.obolibrary.org/obo/GO_1902844 GO:1902841 biolink:BiologicalProcess regulation of netrin-activated signaling pathway Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway. go-plus.json regulation of netrin-activated signal transduction pathway|regulation of netrin signaling pathway|regulation of netrin-activated signalling pathway|regulation of netrin-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902841 GO:1902842 biolink:BiologicalProcess negative regulation of netrin-activated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway. go-plus.json downregulation of netrin signaling pathway|down regulation of netrin-activated signaling pathway|downregulation of netrin-activated signal transduction pathway|inhibition of netrin-activated signaling pathway|downregulation of netrin-mediated signaling pathway|down regulation of netrin signaling pathway|down regulation of netrin-activated signal transduction pathway|inhibition of netrin signaling pathway|inhibition of netrin-activated signal transduction pathway|down-regulation of netrin-activated signalling pathway|negative regulation of netrin-activated signalling pathway|negative regulation of netrin-mediated signaling pathway|down-regulation of netrin-mediated signaling pathway|inhibition of netrin-activated signalling pathway|inhibition of netrin-mediated signaling pathway|down-regulation of netrin-activated signaling pathway|down-regulation of netrin signaling pathway|down-regulation of netrin-activated signal transduction pathway|negative regulation of netrin-activated signal transduction pathway|negative regulation of netrin signaling pathway|down regulation of netrin-activated signalling pathway|downregulation of netrin-activated signaling pathway|down regulation of netrin-mediated signaling pathway|downregulation of netrin-activated signalling pathway http://purl.obolibrary.org/obo/GO_1902842 GO:1902840 biolink:BiologicalProcess positive regulation of nuclear migration along microtubule Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. go-plus.json activation of transport of nucleus by microtubules|up-regulation of transport of nucleus by microtubules|up-regulation of microtubule cytoskeleton-dependent nucleus positioning|activation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of nuclear migration, microtubule-mediated|upregulation of transport of nucleus, microtubule-mediated|upregulation of microtubule-mediated nuclear migration|upregulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of microtubule-dependent nuclear positioning|up-regulation of microtubule-dependent nucleus positioning|up regulation of nuclear migration along microtubule|activation of microtubule-dependent nuclear positioning|activation of nuclear migration along microtubule|positive regulation of microtubule-dependent nuclear positioning|positive regulation of transport of nucleus by microtubules|positive regulation of microtubule cytoskeleton-dependent nucleus positioning|upregulation of nuclear migration, microtubule-mediated|up-regulation of transport of nucleus, microtubule-mediated|activation of transport of nucleus, microtubule-mediated|up-regulation of microtubule-mediated nuclear migration|up regulation of transport of nucleus by microtubules|activation of microtubule-mediated nuclear migration|up regulation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of microtubule cytoskeleton-dependent nuclear positioning|activation of microtubule cytoskeleton-dependent nuclear positioning|upregulation of microtubule-dependent nucleus positioning|up-regulation of nuclear migration along microtubule|up-regulation of microtubule-dependent nuclear positioning|up regulation of nuclear migration, microtubule-mediated|positive regulation of transport of nucleus, microtubule-mediated|upregulation of transport of nucleus by microtubules|activation of nuclear migration, microtubule-mediated|upregulation of microtubule cytoskeleton-dependent nucleus positioning|positive regulation of microtubule-mediated nuclear migration|positive regulation of nuclear migration, microtubule-mediated|positive regulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of transport of nucleus, microtubule-mediated|up regulation of microtubule-dependent nucleus positioning|up regulation of microtubule-mediated nuclear migration|up regulation of microtubule cytoskeleton-dependent nuclear positioning|activation of microtubule-dependent nucleus positioning|positive regulation of microtubule-dependent nucleus positioning|upregulation of microtubule-dependent nuclear positioning|upregulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902840 GO:0048770 biolink:CellularComponent pigment granule A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0048770 GO:0048771 biolink:BiologicalProcess tissue remodeling The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. go-plus.json http://purl.obolibrary.org/obo/GO_0048771 goslim_pir GO:0048772 biolink:BiologicalProcess leucophore differentiation The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance. go-plus.json leucophore cell differentiation http://purl.obolibrary.org/obo/GO_0048772 UBERON:0000030 biolink:AnatomicalEntity lamina propria A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions. go-plus.json tunica propria|lamina propria mucosa|lamina propria mucosae http://purl.obolibrary.org/obo/UBERON_0000030 UBERON:0000035 biolink:AnatomicalEntity primary ovarian follicle An ovarian follicle that has one layer of granulosa cells. go-plus.json folliculus ovaricus primarius|primary follicle of ovary|primary ovarian follicle|ovary primary follicle|primary follicle|preantral follicle of ovary|primary egg follicle http://purl.obolibrary.org/obo/UBERON_0000035 UBERON:0000036 biolink:AnatomicalEntity secondary ovarian follicle A maturing ovarian follicle that has two more more layers of granulosa cells, up to the onset of antrum formation. go-plus.json ovary secondary follicle|preantral follicle|secondary follicle|secondary egg follicle|pre-antral follicle|pre-ovulatory follicle|folliculus ovaricus secondarius|secondary follicle of ovary|antral follicle of ovary http://purl.obolibrary.org/obo/UBERON_0000036 UBERON:0000037 biolink:AnatomicalEntity tertiary ovarian follicle A follicle that has reached the most mature stage of folliculogenesis, characterized by the presence of the antrum go-plus.json folliculi ovarici vesiculosi|folliculus ovaricus tertiarius|antral ovarian follicle|ovary antral follicle|vesicular follicle of ovary|folliculus ovaricus tertiarius (vesiculosus)|folliculus ovaricus tertiarius (vesiculous)|Graafian follicle|tertiary egg follicle|antral follicle|vesicular ovarian follicle|tertiary follicle of ovary http://purl.obolibrary.org/obo/UBERON_0000037 UBERON:0000038 biolink:AnatomicalEntity follicular fluid The fluid surrounding the ovum and granulosa cells in the ovarian follicle. go-plus.json ovary follicle fluid|liquor folliculi|ovarian follicular fluid|liquor follicularis|ovary follicular fluid|liquor folliculi|antral fluid, ovarian follicle http://purl.obolibrary.org/obo/UBERON_0000038 UBERON:0000031 biolink:AnatomicalEntity lamina propria of trachea A lamina propria that is part of a respiratory airway. go-plus.json trachea lamina propria|lamina propria mucosa of trachea|tracheal lamina propria|trachea lamina propria mucosa|windpipe lamina propria mucosae|lamina propria mucosa of windpipe|windpipe lamina propria|lamina propria mucosae of trachea|windpipe lamina propria mucosa|lamina propria mucosae of windpipe|trachea lamina propria mucosae|lamina propria of windpipe http://purl.obolibrary.org/obo/UBERON_0000031 UBERON:0000033 biolink:AnatomicalEntity head The head is the anterior-most division of the body [GO]. go-plus.json head (volume)|adult head|cephalic area http://purl.obolibrary.org/obo/UBERON_0000033 GO:0048784 biolink:BiologicalProcess pigment biosynthetic process involved in pigment granule maturation The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state. go-plus.json pigment biosynthetic process during pigment granule maturation http://purl.obolibrary.org/obo/GO_0048784 GO:0048785 biolink:BiologicalProcess hatching gland development The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process. go-plus.json http://purl.obolibrary.org/obo/GO_0048785 GO:0048786 biolink:CellularComponent presynaptic active zone A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix. NIF_Subcellular:sao792027222 go-plus.json pre-synaptic active zone component|presynaptic specialization|pre-synaptic active zone http://purl.obolibrary.org/obo/GO_0048786 goslim_synapse GO:0048787 biolink:CellularComponent presynaptic active zone membrane The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters. NIF_Subcellular:sao2038461087 go-plus.json active zone presynaptic plasma membrane|active zone pre-synaptic plasma membrane|pre-synaptic active zone membrane|active zone plasma membrane http://purl.obolibrary.org/obo/GO_0048787 goslim_synapse GO:0048788 biolink:CellularComponent cytoskeleton of presynaptic active zone The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites. NIF_Subcellular:sao1470121605 go-plus.json CAZ|synaptic ribbon|presynaptic cytoskeletal matrix assembled at active zones|T-bar ribbon|ribbon|pre-synaptic dense body|T-bar|presynaptic ribbon|active zone cytomatrix|pre-synaptic ribbon|presynaptic dense body|presynaptic cytomatrix assembled at active zones|presynaptic cytoskeletal matrix|pre-synaptic cytoskeletal matrix assembled at active zones http://purl.obolibrary.org/obo/GO_0048788 GO:1902858 biolink:BiologicalProcess propionyl-CoA metabolic process The chemical reactions and pathways involving propionyl-CoA. go-plus.json propionyl-CoA metabolism http://purl.obolibrary.org/obo/GO_1902858 GO:1902859 biolink:BiologicalProcess propionyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of propionyl-CoA. go-plus.json propionyl-CoA breakdown|propionyl-CoA catabolism|propionyl-CoA degradation http://purl.obolibrary.org/obo/GO_1902859 GO:0048789 biolink:BiologicalProcess cytoskeletal matrix organization at active zone The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane. go-plus.json cytoskeletal matrix organisation at active zone http://purl.obolibrary.org/obo/GO_0048789 GO:1902856 biolink:BiologicalProcess negative regulation of non-motile cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly. go-plus.json down-regulation of nonmotile primary cilia assembly|negative regulation of nonmotile primary cilia assembly|negative regulation of sensory cilium biogenesis|down-regulation of sensory cilium biogenesis|negative regulation of immotile primary cilium assembly|down-regulation of immotile primary cilium assembly|downregulation of nonmotile primary cilia assembly|negative regulation of nonmotile primary cilium assembly|down regulation of nonmotile primary cilia assembly|inhibition of sensory cilium biogenesis|down regulation of nonmotile primary cilium assembly|down regulation of sensory cilium assembly|downregulation of immotile primary cilium assembly|downregulation of nonmotile primary cilium assembly|inhibition of immotile primary cilium assembly|downregulation of sensory cilium assembly|down regulation of sensory cilium biogenesis|inhibition of nonmotile primary cilia assembly|down regulation of immotile primary cilium assembly|downregulation of sensory cilium biogenesis|down-regulation of sensory cilium assembly|negative regulation of sensory cilium assembly|down-regulation of nonmotile primary cilium assembly|inhibition of sensory cilium assembly|inhibition of nonmotile primary cilium assembly http://purl.obolibrary.org/obo/GO_1902856 GO:1902857 biolink:BiologicalProcess positive regulation of non-motile cilium assembly Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly. go-plus.json activation of nonmotile primary cilia assembly|up-regulation of immotile primary cilium assembly|up-regulation of nonmotile primary cilium assembly|up-regulation of sensory cilium assembly|activation of sensory cilium biogenesis|positive regulation of nonmotile primary cilia assembly|up regulation of nonmotile primary cilia assembly|positive regulation of nonmotile primary cilium assembly|up-regulation of sensory cilium biogenesis|upregulation of nonmotile primary cilium assembly|upregulation of sensory cilium assembly|positive regulation of immotile primary cilium assembly|up regulation of immotile primary cilium assembly|upregulation of nonmotile primary cilia assembly|upregulation of sensory cilium biogenesis|activation of nonmotile primary cilium assembly|activation of sensory cilium assembly|up regulation of sensory cilium assembly|up regulation of nonmotile primary cilium assembly|positive regulation of sensory cilium assembly|upregulation of immotile primary cilium assembly|up-regulation of nonmotile primary cilia assembly|up regulation of sensory cilium biogenesis|positive regulation of sensory cilium biogenesis|activation of immotile primary cilium assembly http://purl.obolibrary.org/obo/GO_1902857 GO:1902854 biolink:BiologicalProcess positive regulation of nuclear migration during mitotic telophase Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase. go-plus.json upregulation of nuclear migration during mitotic telophase|activation of nuclear migration during mitotic telophase|up-regulation of nuclear migration during mitotic telophase|up regulation of nuclear migration during mitotic telophase http://purl.obolibrary.org/obo/GO_1902854 GO:1902855 biolink:BiologicalProcess regulation of non-motile cilium assembly Any process that modulates the frequency, rate or extent of non-motile cilium assembly. go-plus.json regulation of nonmotile primary cilium assembly|regulation of nonmotile primary cilia assembly|regulation of sensory cilium assembly|regulation of immotile primary cilium assembly|regulation of sensory cilium biogenesis http://purl.obolibrary.org/obo/GO_1902855 GO:1902852 biolink:BiologicalProcess regulation of nuclear migration during mitotic telophase Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase. go-plus.json http://purl.obolibrary.org/obo/GO_1902852 GO:1902853 biolink:BiologicalProcess negative regulation of nuclear migration during mitotic telophase Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase. go-plus.json downregulation of nuclear migration during mitotic telophase|down regulation of nuclear migration during mitotic telophase|inhibition of nuclear migration during mitotic telophase|down-regulation of nuclear migration during mitotic telophase http://purl.obolibrary.org/obo/GO_1902853 GO:1902850 biolink:BiologicalProcess microtubule cytoskeleton organization involved in mitosis Any microtubule cytoskeleton organization that is involved in mitosis. go-plus.json microtubule cytoskeleton organisation involved in mitosis|microtubule dynamics involved in mitosis|microtubule cytoskeleton organization and biogenesis involved in mitosis http://purl.obolibrary.org/obo/GO_1902850 GO:0048780 biolink:BiologicalProcess positive regulation of erythrophore differentiation Any process that activates or increases the frequency, rate or extent of erythrophore differentiation. go-plus.json stimulation of erythrophore differentiation|up-regulation of erythrophore differentiation|activation of erythrophore differentiation|up regulation of erythrophore differentiation|upregulation of erythrophore differentiation http://purl.obolibrary.org/obo/GO_0048780 GO:0048781 biolink:BiologicalProcess regulation of cyanophore differentiation Any process that modulates the frequency, rate or extent of cyanophore differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0048781 GO:0048782 biolink:BiologicalProcess negative regulation of cyanophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation. go-plus.json downregulation of cyanophore differentiation|down regulation of cyanophore differentiation|inhibition of cyanophore differentiation|down-regulation of cyanophore differentiation http://purl.obolibrary.org/obo/GO_0048782 GO:0048783 biolink:BiologicalProcess positive regulation of cyanophore differentiation Any process that activates or increases the frequency, rate or extent of cyanophore differentiation. go-plus.json up regulation of cyanophore differentiation|upregulation of cyanophore differentiation|stimulation of cyanophore differentiation|up-regulation of cyanophore differentiation|activation of cyanophore differentiation http://purl.obolibrary.org/obo/GO_0048783 GO:0097719 biolink:BiologicalProcess neural tissue regeneration The regrowth of neural tissue following its loss or destruction. go-plus.json neuroregeneration http://purl.obolibrary.org/obo/GO_0097719 GO:0097717 biolink:BiologicalProcess copper ion transport across blood-cerebrospinal fluid barrier The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier. go-plus.json copper ion transport across blood/cerebrospinal fluid barrier|copper ion transport across BCB|copper ion transport across blood-CSF barrier|copper ion transport across blood/CSF barrier|copper ion transport across BCSFB http://purl.obolibrary.org/obo/GO_0097717 GO:0097718 biolink:MolecularActivity disordered domain specific binding Binding to a disordered domain of a protein. go-plus.json disordered protein domain specific binding http://purl.obolibrary.org/obo/GO_0097718 GO:0097715 biolink:BiologicalProcess cellular response to viscosity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097715 GO:0097716 biolink:BiologicalProcess copper ion transport across blood-brain barrier The directed movement of copper (Cu) ions passing through the blood-brain barrier. go-plus.json copper ion transport across BBB http://purl.obolibrary.org/obo/GO_0097716 GO:0097713 biolink:MolecularActivity dolichol-phosphate-mannose synthase regulator activity Binds to and modulates the activity of dolichol-phosphate-mannose synthase. go-plus.json http://purl.obolibrary.org/obo/GO_0097713 GO:0097714 biolink:BiologicalProcess response to viscosity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097714 GO:0097711 biolink:BiologicalProcess ciliary basal body-plasma membrane docking The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. Reactome:R-HSA-5620912.1 go-plus.json anchoring of the basal body to the plasma membrane|ciliary basal body docking http://purl.obolibrary.org/obo/GO_0097711 GO:0097712 biolink:BiologicalProcess vesicle targeting, trans-Golgi to periciliary membrane compartment The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. go-plus.json http://purl.obolibrary.org/obo/GO_0097712 GO:0097710 biolink:CellularComponent viral terminase, small subunit The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit. go-plus.json virus terminase, small subunit http://purl.obolibrary.org/obo/GO_0097710 GO:0048795 biolink:BiologicalProcess swim bladder morphogenesis The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. go-plus.json gas bladder morphogenesis http://purl.obolibrary.org/obo/GO_0048795 GO:0048796 biolink:BiologicalProcess swim bladder maturation A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. go-plus.json gas bladder maturation http://purl.obolibrary.org/obo/GO_0048796 GO:0048797 biolink:BiologicalProcess swim bladder formation The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. go-plus.json gas bladder biosynthesis|gas bladder formation http://purl.obolibrary.org/obo/GO_0048797 GO:0048798 biolink:BiologicalProcess swim bladder inflation The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. go-plus.json gas bladder inflation http://purl.obolibrary.org/obo/GO_0048798 GO:1902869 biolink:BiologicalProcess regulation of amacrine cell differentiation Any process that modulates the frequency, rate or extent of amacrine cell differentiation. go-plus.json regulation of amacrine neuron differentiation http://purl.obolibrary.org/obo/GO_1902869 GO:0048799 biolink:BiologicalProcess animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. go-plus.json http://purl.obolibrary.org/obo/GO_0048799 CHEBI:23403 biolink:ChemicalSubstance coumarins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23403 GO:1902867 biolink:BiologicalProcess negative regulation of retina development in camera-type eye Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. go-plus.json down regulation of retina development in camera-type eye|downregulation of retina development in camera-type eye|down-regulation of retinal development|down-regulation of retina development in camera-style eye|negative regulation of retinal development|negative regulation of retina development in camera-style eye|down-regulation of retina development in camera-type eye|downregulation of retina development in camera-style eye|inhibition of retina development in camera-type eye|inhibition of retinal development|down regulation of retina development in camera-style eye|inhibition of retina development in camera-style eye|down regulation of retinal development|downregulation of retinal development http://purl.obolibrary.org/obo/GO_1902867 CHEBI:23401 biolink:ChemicalSubstance coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23401 GO:1902868 biolink:BiologicalProcess positive regulation of retina development in camera-type eye Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. go-plus.json up-regulation of retina development in camera-style eye|up regulation of retinal development|activation of retina development in camera-style eye|positive regulation of retinal development|up regulation of retina development in camera-type eye|activation of retina development in camera-type eye|activation of retinal development|positive regulation of retina development in camera-style eye|up-regulation of retinal development|up regulation of retina development in camera-style eye|up-regulation of retina development in camera-type eye|upregulation of retinal development|upregulation of retina development in camera-style eye|upregulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902868 GO:1902865 biolink:BiologicalProcess positive regulation of embryonic camera-type eye development Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. go-plus.json up regulation of embryonic camera-type eye development|activation of embryonic camera-type eye development|up regulation of embryonic eye development|activation of embryonic eye development|positive regulation of embryonic eye development|up-regulation of embryonic camera-type eye development|up-regulation of embryonic eye development|upregulation of embryonic camera-type eye development|upregulation of embryonic eye development http://purl.obolibrary.org/obo/GO_1902865 GO:1902866 biolink:BiologicalProcess regulation of retina development in camera-type eye Any process that modulates the frequency, rate or extent of retina development in camera-type eye. go-plus.json regulation of retina development in camera-style eye|regulation of retinal development http://purl.obolibrary.org/obo/GO_1902866 GO:1902863 biolink:BiologicalProcess regulation of embryonic camera-type eye development Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. go-plus.json regulation of embryonic eye development http://purl.obolibrary.org/obo/GO_1902863 GO:0048790 biolink:BiologicalProcess maintenance of presynaptic active zone structure A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters. go-plus.json maintenance of pre-synaptic active zone structure http://purl.obolibrary.org/obo/GO_0048790 goslim_synapse GO:1902864 biolink:BiologicalProcess negative regulation of embryonic camera-type eye development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. go-plus.json down-regulation of embryonic camera-type eye development|down-regulation of embryonic eye development|negative regulation of embryonic eye development|inhibition of embryonic camera-type eye development|inhibition of embryonic eye development|down regulation of embryonic camera-type eye development|down regulation of embryonic eye development|downregulation of embryonic camera-type eye development|downregulation of embryonic eye development http://purl.obolibrary.org/obo/GO_1902864 GO:1902861 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902861 GO:0048791 biolink:BiologicalProcess calcium ion-regulated exocytosis of neurotransmitter The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels. go-plus.json http://purl.obolibrary.org/obo/GO_0048791 GO:1902862 biolink:BiologicalProcess obsolete glycerol catabolic process to glycerone phosphate OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycerol to glycerone phosphate. go-plus.json glycerol catabolism to glycerone phosphate|glycerol breakdown to glycerone phosphate|glycerol degradation to glycerone phosphate|glycerol catabolic process to glycerone phosphate http://purl.obolibrary.org/obo/GO_1902862 GO:0048792 biolink:BiologicalProcess spontaneous exocytosis of neurotransmitter The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell. go-plus.json spontaneous synaptic vesicle exocytosis http://purl.obolibrary.org/obo/GO_0048792 GO:0048793 biolink:BiologicalProcess pronephros development The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. go-plus.json pronephric kidney development http://purl.obolibrary.org/obo/GO_0048793 GO:1902860 biolink:BiologicalProcess propionyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of propionyl-CoA. go-plus.json propionyl-CoA biosynthesis|propionyl-CoA anabolism|propionyl-CoA synthesis|propionyl-CoA formation http://purl.obolibrary.org/obo/GO_1902860 GO:0048794 biolink:BiologicalProcess swim bladder development The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. go-plus.json gas bladder development http://purl.obolibrary.org/obo/GO_0048794 UBERON:0000093 biolink:AnatomicalEntity sulcus A depression or fissure in the surface of an organ. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000093 UBERON:0000094 biolink:AnatomicalEntity membrane organ Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA] go-plus.json membrane of organ|membrane http://purl.obolibrary.org/obo/UBERON_0000094 UBERON:0000095 biolink:AnatomicalEntity cardiac neural crest portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia] go-plus.json complexus cristae neuralis cardiacus|cardiac neural crest complex http://purl.obolibrary.org/obo/UBERON_0000095 GO:0097728 biolink:CellularComponent 9+0 motile cilium A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme). go-plus.json motile 9+0 cilium|nodal cilium http://purl.obolibrary.org/obo/GO_0097728 UBERON:0000091 biolink:AnatomicalEntity bilaminar disc A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. go-plus.json bilaminar disk|embryonic disc|bilaminary germ disc|germinal disk|bilaminary embryonic disc|embryonic shield|germinal disc http://purl.obolibrary.org/obo/UBERON_0000091 GO:0097729 biolink:CellularComponent 9+2 motile cilium A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). go-plus.json conventional motile cilium|motile 9+2 cilium|sperm flagellum http://purl.obolibrary.org/obo/GO_0097729 UBERON:0000092 biolink:AnatomicalEntity post-embryonic stage stage succeeding embryo, including mature structure go-plus.json postembryonic stage|postembryonic|post-hatching stage http://purl.obolibrary.org/obo/UBERON_0000092 GO:0097726 biolink:MolecularActivity LEM domain binding Binding to a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF). go-plus.json lamina-associated polypeptide, emerin, MAN1 domain binding|LAP2, emerin, MAN1 domain binding http://purl.obolibrary.org/obo/GO_0097726 GO:0097727 biolink:CellularComponent blepharoplast An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097727 GO:0097724 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097724 GO:0097725 biolink:BiologicalProcess histone H3-K79 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone. go-plus.json histone H3 K79 dimethylation|histone lysine H3 K79 dimethylation http://purl.obolibrary.org/obo/GO_0097725 GO:0097722 biolink:BiologicalProcess sperm motility Any process involved in the controlled movement of a sperm cell. go-plus.json sperm movement http://purl.obolibrary.org/obo/GO_0097722 gocheck_do_not_annotate GO:0097723 biolink:BiologicalProcess amoeboid sperm motility Any process involved in the controlled movement of an amoeboid sperm cell. go-plus.json ameboid sperm movement|amoeboid sperm movement|ameboid sperm motility http://purl.obolibrary.org/obo/GO_0097723 GO:0097720 biolink:BiologicalProcess calcineurin-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression. go-plus.json calcineurin signaling|calcineurin-mediated signalling http://purl.obolibrary.org/obo/GO_0097720 GO:0097721 biolink:CellularComponent ciliary vesicle A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle. go-plus.json primary ciliary vesicle|CV http://purl.obolibrary.org/obo/GO_0097721 GO:1902878 biolink:BiologicalProcess obsolete regulation of BMP signaling pathway involved in spinal cord association neuron specification OBSOLETE. Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification. go-plus.json regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|regulation of BMP signalling pathway involved in spinal cord association neuron specification|regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification http://purl.obolibrary.org/obo/GO_1902878 GO:1902879 biolink:BiologicalProcess obsolete negative regulation of BMP signaling pathway involved in spinal cord association neuron specification OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification. go-plus.json inhibition of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of BMP signalling pathway involved in spinal cord association neuron specification|downregulation of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of BMP signalling pathway involved in spinal cord association neuron specification|down regulation of BMP signaling pathway involved in spinal cord association neuron specification|inhibition of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|negative regulation of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification http://purl.obolibrary.org/obo/GO_1902879 GO:1902876 biolink:BiologicalProcess negative regulation of embryonic pattern specification Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification. go-plus.json down regulation of embryonic pattern specification|down-regulation of ventral/lateral system|downregulation of embryonic pattern specification|negative regulation of ventral/lateral system|down-regulation of embryonic pattern specification|downregulation of ventral/lateral system|down regulation of ventral/lateral system|inhibition of embryonic pattern specification|inhibition of ventral/lateral system http://purl.obolibrary.org/obo/GO_1902876 GO:1902877 biolink:BiologicalProcess positive regulation of embryonic pattern specification Any process that activates or increases the frequency, rate or extent of embryonic pattern specification. go-plus.json up-regulation of ventral/lateral system|upregulation of embryonic pattern specification|activation of ventral/lateral system|up regulation of embryonic pattern specification|positive regulation of ventral/lateral system|activation of embryonic pattern specification|up regulation of ventral/lateral system|upregulation of ventral/lateral system|up-regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_1902877 GO:1902874 biolink:BiologicalProcess positive regulation of horizontal cell localization Any process that activates or increases the frequency, rate or extent of horizontal cell localization. go-plus.json activation of horizontal cell positioning|positive regulation of horizontal cell positioning|positive regulation of horizontal cell localisation|up regulation of horizontal cell localisation|upregulation of retinal horizontal cell positioning|positive regulation of laminar positioning of retinal horizontal cell|up regulation of laminar positioning of retinal horizontal cell|up regulation of horizontal cell localization|up-regulation of horizontal cell positioning|upregulation of horizontal cell localisation|up regulation of retinal horizontal cell positioning|activation of retinal horizontal cell positioning|positive regulation of retinal horizontal cell positioning|upregulation of laminar positioning of retinal horizontal cell|upregulation of horizontal cell localization|upregulation of horizontal cell positioning|up-regulation of horizontal cell localisation|activation of horizontal cell localisation|up-regulation of laminar positioning of retinal horizontal cell|up-regulation of retinal horizontal cell positioning|activation of laminar positioning of retinal horizontal cell|up-regulation of horizontal cell localization|up regulation of horizontal cell positioning|activation of horizontal cell localization http://purl.obolibrary.org/obo/GO_1902874 GO:1902875 biolink:BiologicalProcess regulation of embryonic pattern specification Any process that modulates the frequency, rate or extent of embryonic pattern specification. go-plus.json regulation of embryonic pattern formation|regulation of ventral/lateral system|regulation of embryonic pattern biosynthesis http://purl.obolibrary.org/obo/GO_1902875 GO:1902872 biolink:BiologicalProcess regulation of horizontal cell localization Any process that modulates the frequency, rate or extent of horizontal cell localization. go-plus.json regulation of horizontal cell localisation|regulation of retinal horizontal cell positioning|regulation of laminar positioning of retinal horizontal cell|regulation of horizontal cell positioning http://purl.obolibrary.org/obo/GO_1902872 GO:1902873 biolink:BiologicalProcess negative regulation of horizontal cell localization Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization. go-plus.json down-regulation of laminar positioning of retinal horizontal cell|negative regulation of laminar positioning of retinal horizontal cell|down-regulation of horizontal cell positioning|down-regulation of horizontal cell localization|negative regulation of horizontal cell positioning|downregulation of horizontal cell localisation|down regulation of retinal horizontal cell positioning|downregulation of laminar positioning of retinal horizontal cell|down regulation of horizontal cell localisation|downregulation of retinal horizontal cell positioning|inhibition of horizontal cell positioning|inhibition of horizontal cell localisation|down regulation of laminar positioning of retinal horizontal cell|downregulation of horizontal cell localization|inhibition of laminar positioning of retinal horizontal cell|down regulation of horizontal cell localization|down-regulation of retinal horizontal cell positioning|negative regulation of retinal horizontal cell positioning|inhibition of horizontal cell localization|down regulation of horizontal cell positioning|inhibition of retinal horizontal cell positioning|downregulation of horizontal cell positioning|negative regulation of horizontal cell localisation|down-regulation of horizontal cell localisation http://purl.obolibrary.org/obo/GO_1902873 GO:1902870 biolink:BiologicalProcess negative regulation of amacrine cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation. go-plus.json down regulation of amacrine cell differentiation|inhibition of amacrine neuron differentiation|downregulation of amacrine cell differentiation|down-regulation of amacrine cell differentiation|down regulation of amacrine neuron differentiation|downregulation of amacrine neuron differentiation|inhibition of amacrine cell differentiation|down-regulation of amacrine neuron differentiation|negative regulation of amacrine neuron differentiation http://purl.obolibrary.org/obo/GO_1902870 GO:1902871 biolink:BiologicalProcess positive regulation of amacrine cell differentiation Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation. go-plus.json upregulation of amacrine cell differentiation|up-regulation of amacrine neuron differentiation|up regulation of amacrine cell differentiation|activation of amacrine cell differentiation|upregulation of amacrine neuron differentiation|up-regulation of amacrine cell differentiation|up regulation of amacrine neuron differentiation|activation of amacrine neuron differentiation|positive regulation of amacrine neuron differentiation http://purl.obolibrary.org/obo/GO_1902871 GO:0034198 biolink:BiologicalProcess cellular response to amino acid starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. go-plus.json general amino acid control response|GAAC response http://purl.obolibrary.org/obo/GO_0034198 GO:0034199 biolink:BiologicalProcess activation of protein kinase A activity Any process that initiates the activity of the inactive enzyme protein kinase A. go-plus.json protein kinase A activation http://purl.obolibrary.org/obo/GO_0034199 GO:1902880 biolink:BiologicalProcess obsolete positive regulation of BMP signaling pathway involved in spinal cord association neuron specification OBSOLETE. Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification. go-plus.json activation of BMP signalling pathway involved in spinal cord association neuron specification|positive regulation of BMP signalling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up-regulation of BMP signaling pathway involved in spinal cord association neuron specification|activation of BMP signaling pathway involved in spinal cord association neuron specification|up-regulation of BMP signalling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|upregulation of BMP signalling pathway involved in spinal cord association neuron specification|up regulation of BMP signaling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up regulation of BMP signalling pathway involved in spinal cord association neuron specification|upregulation of BMP signaling pathway involved in spinal cord association neuron specification http://purl.obolibrary.org/obo/GO_1902880 UBERON:0000083 biolink:AnatomicalEntity mesonephric tubule A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]. go-plus.json tubuli mesonephrici|renal tubules http://purl.obolibrary.org/obo/UBERON_0000083 UBERON:0000084 biolink:AnatomicalEntity ureteric bud An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP] go-plus.json gemma ureterica|diverticulum metanephricum|ureteric diverticulum|metanephric bud|metanephric diverticulum|ureteric ampulla|diverticulum http://purl.obolibrary.org/obo/UBERON_0000084 UBERON:0000085 biolink:AnatomicalEntity morula A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. go-plus.json morula (2-16 cells) http://purl.obolibrary.org/obo/UBERON_0000085 UBERON:0000080 biolink:AnatomicalEntity mesonephros The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo. go-plus.json mesonephroi|opisto nephros|corpus Wolffi|amphibian adult kidney|middle kidney|Wolffian body|opistonephros|mesonephric kidney|opisthonephros http://purl.obolibrary.org/obo/UBERON_0000080 UBERON:0000081 biolink:AnatomicalEntity metanephros In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO] go-plus.json definite kidney|hind kidney|metanephric kidney|metanephron|definitive kidney http://purl.obolibrary.org/obo/UBERON_0000081 GO:0034190 biolink:MolecularActivity apolipoprotein receptor binding Binding to an apolipoprotein receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0034190 GO:0034191 biolink:MolecularActivity apolipoprotein A-I receptor binding Binding to an apolipoprotein A-I receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0034191 GO:0034192 biolink:BiologicalProcess D-galactonate metabolic process The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid. go-plus.json D-galactonate metabolism http://purl.obolibrary.org/obo/GO_0034192 GO:0034193 biolink:BiologicalProcess L-galactonate metabolic process The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid. go-plus.json L-galactonate metabolism http://purl.obolibrary.org/obo/GO_0034193 UBERON:0000086 biolink:AnatomicalEntity zona pellucida A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes. go-plus.json vitelline envelope|pellucid zone|striated membrane|oolemma|zona radiata|zona striata|zona pellucida - vitelline membrane|vitelline membrane http://purl.obolibrary.org/obo/UBERON_0000086 GO:0034194 biolink:BiologicalProcess D-galactonate catabolic process The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid. MetaCyc:GALACTCAT-PWY go-plus.json D-galactonate degradation|D-galactonate breakdown|D-galactonate catabolism http://purl.obolibrary.org/obo/GO_0034194 GO:0034195 biolink:BiologicalProcess L-galactonate catabolic process The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid. MetaCyc:GALACTCAT-PWY go-plus.json L-galactonate degradation|L-galactonate breakdown|L-galactonate catabolism http://purl.obolibrary.org/obo/GO_0034195 UBERON:0000087 biolink:AnatomicalEntity inner cell mass A mass of cells that develop into the body of the embryo and some extraembryonic tissues go-plus.json ICM|early embryoblast|embryoblast|pluriblast|embryoblastus; massa cellularis interna; pluriblastus senior http://purl.obolibrary.org/obo/UBERON_0000087 GO:0034196 biolink:BiologicalProcess acylglycerol transport The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids. go-plus.json glyceride transport http://purl.obolibrary.org/obo/GO_0034196 UBERON:0000088 biolink:AnatomicalEntity trophoblast the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta go-plus.json trophoblastus|massa cellularis externa|trophoblast layer|trophoderm http://purl.obolibrary.org/obo/UBERON_0000088 GO:0034197 biolink:BiologicalProcess triglyceride transport The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins. go-plus.json triacylglycerol transport http://purl.obolibrary.org/obo/GO_0034197 UBERON:0000089 biolink:AnatomicalEntity hypoblast (generic) . go-plus.json hypoblast|future endoderm and mesoderm|mesendoderm|hypoblastus|endomesoderm http://purl.obolibrary.org/obo/UBERON_0000089 GO:1902889 biolink:BiologicalProcess protein localization to spindle microtubule A process in which a protein is transported to, or maintained in, a location within a spindle microtubule. go-plus.json protein localisation to spindle microtubule|protein localization in spindle microtubule|protein localisation in spindle microtubule http://purl.obolibrary.org/obo/GO_1902889 GO:1902887 biolink:BiologicalProcess obsolete positive regulation of proteasome-activating ATPase activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity. go-plus.json up-regulation of proteasomal ATPase activity|up-regulation of proteasome channel gating activity|up regulation of proteasome channel opening activity|positive regulation of proteasome channel opening activity|up regulation of proteasome-activating ATPase activity|up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|activation of proteasome channel gating activity|activation of proteasome-activating ATPase activity|upregulation of proteasomal ATPase activity|activation of proteasome channel opening activity|positive regulation of proteasome channel gating activity|up regulation of proteasome channel gating activity|upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|up-regulation of proteasome channel opening activity|up-regulation of proteasome-activating ATPase activity|up regulation of proteasomal ATPase activity|activation of proteasomal ATPase activity|positive regulation of proteasomal ATPase activity|upregulation of proteasome channel opening activity|upregulation of proteasome channel gating activity|up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|activation of ATPase involved in positive regulation of proteasomal protein catabolic process|upregulation of proteasome-activating ATPase activity http://purl.obolibrary.org/obo/GO_1902887 GO:1902888 biolink:BiologicalProcess protein localization to astral microtubule A process in which a protein is transported to, or maintained in, a location within an astral microtubule. go-plus.json protein localisation to astral microtubule|protein localisation in astral microtubule|protein localization in astral microtubule http://purl.obolibrary.org/obo/GO_1902888 GO:1902885 biolink:BiologicalProcess obsolete regulation of proteasome-activating ATPase activity OBSOLETE. Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity. go-plus.json regulation of proteasomal ATPase activity|regulation of proteasome channel gating activity|regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|regulation of proteasome channel opening activity http://purl.obolibrary.org/obo/GO_1902885 GO:1902886 biolink:BiologicalProcess obsolete negative regulation of proteasome-activating ATPase activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity. go-plus.json down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|inhibition of proteasomal ATPase activity|downregulation of proteasome channel opening activity|downregulation of proteasome-activating ATPase activity|inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of proteasome channel opening activity|down-regulation of proteasome channel opening activity|negative regulation of proteasome channel gating activity|down-regulation of proteasome channel gating activity|down-regulation of proteasome-activating ATPase activity|down regulation of proteasomal ATPase activity|downregulation of proteasomal ATPase activity|downregulation of proteasome channel gating activity|down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|inhibition of proteasome-activating ATPase activity|inhibition of proteasome channel opening activity|down regulation of proteasome channel gating activity|downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of proteasomal ATPase activity|down-regulation of proteasomal ATPase activity|down regulation of proteasome channel opening activity|inhibition of proteasome channel gating activity|down regulation of proteasome-activating ATPase activity http://purl.obolibrary.org/obo/GO_1902886 GO:1902883 biolink:BiologicalProcess negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress. go-plus.json down regulation of response to oxidative stress|inhibition of response to oxidative stress|down-regulation of response to oxidative stress|downregulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902883 GO:1902884 biolink:BiologicalProcess positive regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stress. go-plus.json upregulation of response to oxidative stress|up-regulation of response to oxidative stress|activation of response to oxidative stress|up regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902884 GO:1902881 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902881 GO:1902882 biolink:BiologicalProcess regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of response to oxidative stress. go-plus.json http://purl.obolibrary.org/obo/GO_1902882 GO:1902890 biolink:BiologicalProcess regulation of root hair elongation Any process that modulates the frequency, rate or extent of root hair elongation. go-plus.json http://purl.obolibrary.org/obo/GO_1902890 GO:0034187 biolink:MolecularActivity obsolete apolipoprotein E binding OBSOLETE. Binding to apolipoprotein E. go-plus.json apolipoprotein E binding http://purl.obolibrary.org/obo/GO_0034187 UBERON:0000071 biolink:AnatomicalEntity death stage End of the life of an organism. go-plus.json death http://purl.obolibrary.org/obo/UBERON_0000071 GO:0034188 biolink:MolecularActivity apolipoprotein A-I receptor activity Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0034188 GO:1902891 biolink:BiologicalProcess negative regulation of root hair elongation Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation. go-plus.json down-regulation of root hair elongation|downregulation of root hair elongation|down regulation of root hair elongation|inhibition of root hair elongation http://purl.obolibrary.org/obo/GO_1902891 UBERON:0000072 biolink:AnatomicalEntity proximo-distal subdivision of respiratory tract An section of a respiratory tract. go-plus.json respiratory tract|subdivision of respiratory tract http://purl.obolibrary.org/obo/UBERON_0000072 GO:0034189 biolink:MolecularActivity very-low-density lipoprotein particle binding Binding to a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. go-plus.json very-low-density lipoprotein binding|VLDL binding http://purl.obolibrary.org/obo/GO_0034189 UBERON:0000073 biolink:AnatomicalEntity regional part of nervous system Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. go-plus.json part of nervous system http://purl.obolibrary.org/obo/UBERON_0000073 UBERON:0000074 biolink:AnatomicalEntity renal glomerulus A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]. go-plus.json glomerular capillary tuft|Malpighian glomerulus|glomerulus|Malphigian glomerulus|renal corpuscle|glomerular tuft|renal glomeruli|Malpighian tuft|glomerulus renis http://purl.obolibrary.org/obo/UBERON_0000074 GO:0097708 biolink:CellularComponent intracellular vesicle Any vesicle that is part of the intracellular region. go-plus.json http://purl.obolibrary.org/obo/GO_0097708 GO:0097709 biolink:BiologicalProcess connective tissue replacement The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared. go-plus.json http://purl.obolibrary.org/obo/GO_0097709 GO:0097706 biolink:BiologicalProcess vascular endothelial cell response to oscillatory fluid shear stress Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell. go-plus.json blood vessel endothelial cell response to oscillatory fluid shear stress http://purl.obolibrary.org/obo/GO_0097706 UBERON:0000070 biolink:AnatomicalEntity pupal stage A life cycle stage of holometabolous insects in which the organism is a pupa and starts with the larval-pupal apolysis and ends with pupal-adult apolysis. go-plus.json chrysalis stage|chrysalides stage|pupa stage|aurelia stage http://purl.obolibrary.org/obo/UBERON_0000070 GO:0097707 biolink:BiologicalProcess ferroptosis A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes. go-plus.json iron-dependent programmed cell death http://purl.obolibrary.org/obo/GO_0097707 GO:0097704 biolink:BiologicalProcess cellular response to oscillatory fluid shear stress Any response to oscillatory fluid shear stress that occurs at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097704 UBERON:0000079 biolink:AnatomicalEntity male reproductive system The organs associated with producing offspring in the gender that produces spermatozoa. go-plus.json male organism genitalia|male genital tract|male genitals|male genital organ|male reproductive tract|genitalia of male organism|male genital system|male organism reproductive system|male genitalia|reproductive system of male organism|systema genitale masculinum http://purl.obolibrary.org/obo/UBERON_0000079 GO:0097705 biolink:BiologicalProcess vascular endothelial cell response to pulsatile fluid shear stress Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell. go-plus.json blood vessel endothelial cell response to pulsatile fluid shear stress http://purl.obolibrary.org/obo/GO_0097705 GO:0034180 biolink:BiologicalProcess negative regulation of toll-like receptor 13 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway. go-plus.json negative regulation of TLR13 signaling pathway|negative regulation of toll-like receptor 13 signalling pathway http://purl.obolibrary.org/obo/GO_0034180 GO:0097702 biolink:BiologicalProcess response to oscillatory fluid shear stress Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis. go-plus.json http://purl.obolibrary.org/obo/GO_0097702 GO:0034181 biolink:BiologicalProcess positive regulation of toll-like receptor 13 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway. go-plus.json positive regulation of TLR13 signaling pathway|positive regulation of toll-like receptor 13 signalling pathway http://purl.obolibrary.org/obo/GO_0034181 GO:0097703 biolink:BiologicalProcess cellular response to pulsatile fluid shear stress Any response to pulsatile fluid shear stress that occurs at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097703 GO:0034182 biolink:BiologicalProcess regulation of maintenance of mitotic sister chromatid cohesion Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034182 GO:0097700 biolink:BiologicalProcess vascular endothelial cell response to laminar fluid shear stress Any response to laminar fluid shear stress in a vascular endothelial cell. go-plus.json blood vessel endothelial cell response to laminar fluid shear stress http://purl.obolibrary.org/obo/GO_0097700 UBERON:0000075 biolink:AnatomicalEntity subdivision of skeletal system Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. go-plus.json skeletal system part|skeletal system subdivision http://purl.obolibrary.org/obo/UBERON_0000075 GO:0034183 biolink:BiologicalProcess negative regulation of maintenance of mitotic sister chromatid cohesion Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034183 GO:0097701 biolink:BiologicalProcess response to pulsatile fluid shear stress Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects. go-plus.json http://purl.obolibrary.org/obo/GO_0097701 UBERON:0000076 biolink:AnatomicalEntity external ectoderm The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. go-plus.json surface (external) ectoderm|surface ectoderm http://purl.obolibrary.org/obo/UBERON_0000076 GO:0034184 biolink:BiologicalProcess positive regulation of maintenance of mitotic sister chromatid cohesion Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034184 GO:0034185 biolink:MolecularActivity apolipoprotein binding Binding to an apolipoprotein, the protein component of a lipoprotein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034185 UBERON:0000077 biolink:AnatomicalEntity mixed endoderm/mesoderm-derived structure An anatomical structure that develops from the endoderm and the mesoderm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000077 GO:0034186 biolink:MolecularActivity apolipoprotein A-I binding Binding to apolipoprotein A-I. go-plus.json http://purl.obolibrary.org/obo/GO_0034186 UBERON:0000078 biolink:AnatomicalEntity mixed ectoderm/mesoderm/endoderm-derived structure An anatomical structure that develops from the ectoderm, mesoderm and endoderm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000078 GO:0000960 biolink:BiologicalProcess regulation of mitochondrial RNA catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. go-plus.json http://purl.obolibrary.org/obo/GO_0000960 CHEBI:23399 biolink:ChemicalSubstance coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23399 OBO:uberon/core#synapsed_by biolink:OntologyClass synapsed by Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. synapsed_by go-plus.json http://purl.obolibrary.org/obo/uberon/core#synapsed_by GO:0000961 biolink:BiologicalProcess negative regulation of mitochondrial RNA catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. go-plus.json http://purl.obolibrary.org/obo/GO_0000961 GO:0000962 biolink:BiologicalProcess positive regulation of mitochondrial RNA catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. go-plus.json http://purl.obolibrary.org/obo/GO_0000962 GO:0000963 biolink:BiologicalProcess mitochondrial RNA processing The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0000963 GO:0048900 biolink:BiologicalProcess anterior lateral line neuromast primordium migration The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop. go-plus.json ALL neuromast primordium migration http://purl.obolibrary.org/obo/GO_0048900 GO:0048901 biolink:BiologicalProcess anterior lateral line neuromast development The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. go-plus.json http://purl.obolibrary.org/obo/GO_0048901 CHEBI:23392 biolink:ChemicalSubstance corrins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23392 CHEBI:23390 biolink:ChemicalSubstance cobalt-corrinoid hexaamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23390 CHEBI:23396 biolink:ChemicalSubstance cortisol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_23396 UBERON:0000101 biolink:AnatomicalEntity lobe of lung A lung lobe is one of the rounded projections that compose the lung[GO]. go-plus.json lung lobe|pulmonary lobe|pulminory lobe http://purl.obolibrary.org/obo/UBERON_0000101 GO:0048902 biolink:BiologicalProcess anterior lateral line neuromast deposition The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line. go-plus.json http://purl.obolibrary.org/obo/GO_0048902 GO:0000968 biolink:BiologicalProcess tRNA exon ligation An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed. go-plus.json http://purl.obolibrary.org/obo/GO_0000968 GO:0000969 biolink:BiologicalProcess tRNA exon ligation utilizing ATP as source of linkage phosphate A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species. go-plus.json http://purl.obolibrary.org/obo/GO_0000969 GO:0048903 biolink:BiologicalProcess anterior lateral line neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0048903 UBERON:0000102 biolink:AnatomicalEntity lung vasculature The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]. go-plus.json lung vascular network|vasculature of lung|pulmonary vasculature|vascular network of lung http://purl.obolibrary.org/obo/UBERON_0000102 GO:0048904 biolink:BiologicalProcess anterior lateral line neuromast cupula development The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter. go-plus.json http://purl.obolibrary.org/obo/GO_0048904 UBERON:0000104 biolink:AnatomicalEntity life cycle An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism. go-plus.json entire life cycle|lifespan|life|entire lifespan http://purl.obolibrary.org/obo/UBERON_0000104 GO:0048905 biolink:BiologicalProcess anterior lateral line neuromast mantle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0048905 GO:0000964 biolink:BiologicalProcess mitochondrial RNA 5'-end processing Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion. go-plus.json mitochondrial RNA 5' end processing http://purl.obolibrary.org/obo/GO_0000964 GO:0048906 biolink:BiologicalProcess anterior lateral line neuromast support cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048906 GO:0048907 biolink:BiologicalProcess anterior lateral line ganglion development The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear. go-plus.json gALL development http://purl.obolibrary.org/obo/GO_0048907 GO:0000965 biolink:BiologicalProcess mitochondrial RNA 3'-end processing Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion. go-plus.json mitochondrial RNA 3' end processing http://purl.obolibrary.org/obo/GO_0000965 GO:0000966 biolink:BiologicalProcess RNA 5'-end processing Any process involved in forming the mature 5' end of an RNA molecule. go-plus.json RNA 5' end processing http://purl.obolibrary.org/obo/GO_0000966 GO:0048908 biolink:BiologicalProcess anterior lateral line ganglion neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion. go-plus.json http://purl.obolibrary.org/obo/GO_0048908 GO:0000967 biolink:BiologicalProcess rRNA 5'-end processing Any process involved in forming the mature 5' end of an rRNA molecule. go-plus.json rRNA 5' end processing http://purl.obolibrary.org/obo/GO_0000967 GO:0048909 biolink:BiologicalProcess anterior lateral line nerve development The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. go-plus.json nALL development|ALLN development|rostral lateral line nerve development http://purl.obolibrary.org/obo/GO_0048909 GO:0000971 biolink:BiologicalProcess tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans. go-plus.json http://purl.obolibrary.org/obo/GO_0000971 GO:0000972 biolink:BiologicalProcess transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000972 CHEBI:47356 biolink:ChemicalSubstance 7-chloro-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_47356 GO:0000973 biolink:BiologicalProcess posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed. go-plus.json http://purl.obolibrary.org/obo/GO_0000973 GO:0000974 biolink:CellularComponent Prp19 complex A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. go-plus.json Prp19/CDC5 complex|nineteen complex|NTC http://purl.obolibrary.org/obo/GO_0000974 GO:0048910 biolink:BiologicalProcess afferent axon development in anterior lateral line nerve The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048910 GO:0048911 biolink:BiologicalProcess efferent axon development in anterior lateral line nerve The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048911 GO:0048912 biolink:BiologicalProcess glial cell migration in anterior lateral line nerve The movement of a glial cell along the axons in the anterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048912 GO:0000970 biolink:BiologicalProcess tRNA exon ligation utilizing GTP as source of linkage phosphate A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process. go-plus.json http://purl.obolibrary.org/obo/GO_0000970 CHEBI:86962 biolink:ChemicalSubstance veratryl glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_86962 chebi_ph7_3 CHEBI:86963 biolink:ChemicalSubstance veratrylglycerol beta-guaiacyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_86963 chebi_ph7_3 GO:0009300 biolink:BiologicalProcess antisense RNA transcription The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0009300 GO:0009301 biolink:BiologicalProcess snRNA transcription The synthesis of small nuclear RNA (snRNA) from a DNA template. go-plus.json http://purl.obolibrary.org/obo/GO_0009301 GO:0009302 biolink:BiologicalProcess sno(s)RNA transcription The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template. go-plus.json sRNA transcription|snoRNA transcription http://purl.obolibrary.org/obo/GO_0009302 GO:0009303 biolink:BiologicalProcess rRNA transcription The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. go-plus.json rRNA synthesis|rRNA biosynthetic process|rRNA biosynthesis http://purl.obolibrary.org/obo/GO_0009303 GO:0009304 biolink:BiologicalProcess tRNA transcription The synthesis of transfer RNA (tRNA) from a DNA template. go-plus.json tRNA synthesis|tRNA biosynthetic process|tRNA biosynthesis http://purl.obolibrary.org/obo/GO_0009304 GO:0048913 biolink:BiologicalProcess anterior lateral line nerve glial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048913 GO:0000979 biolink:MolecularActivity RNA polymerase II core promoter sequence-specific DNA binding Binding to a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene. go-plus.json http://purl.obolibrary.org/obo/GO_0000979 GO:0009305 biolink:BiologicalProcess protein biotinylation The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid. go-plus.json protein amino acid biotinylation http://purl.obolibrary.org/obo/GO_0009305 GO:0048914 biolink:BiologicalProcess myelination of anterior lateral line nerve axons The formation of compact myelin sheaths around the axons of the anterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048914 GO:0009306 biolink:BiologicalProcess protein secretion The controlled release of proteins from a cell. go-plus.json protein secretion resulting in cell fate commitment|protein secretion during cell fate commitment|glycoprotein secretion http://purl.obolibrary.org/obo/GO_0009306 goslim_drosophila GO:0009307 biolink:BiologicalProcess DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme. go-plus.json DNA restriction http://purl.obolibrary.org/obo/GO_0009307 GO:0048915 biolink:BiologicalProcess posterior lateral line system development The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. go-plus.json PLL http://purl.obolibrary.org/obo/GO_0048915 GO:0009308 biolink:BiologicalProcess amine metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. go-plus.json amine metabolism http://purl.obolibrary.org/obo/GO_0009308 goslim_chembl|goslim_pir GO:0048916 biolink:BiologicalProcess posterior lateral line development The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear. go-plus.json PLL development http://purl.obolibrary.org/obo/GO_0048916 GO:0048917 biolink:BiologicalProcess posterior lateral line ganglion development The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear. go-plus.json gPLL development http://purl.obolibrary.org/obo/GO_0048917 GO:0000975 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000975 GO:0009309 biolink:BiologicalProcess amine biosynthetic process The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. go-plus.json amine biosynthesis|amine anabolism|amine synthesis|amine formation http://purl.obolibrary.org/obo/GO_0009309 GO:0048918 biolink:BiologicalProcess posterior lateral line nerve development The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. go-plus.json caudal lateral line nerve development|PLLN development http://purl.obolibrary.org/obo/GO_0048918 GO:0000976 biolink:MolecularActivity transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. go-plus.json transcription regulatory region DNA binding|regulatory region DNA binding|transcription regulatory region sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0000976 GO:0000977 biolink:MolecularActivity RNA polymerase II transcription regulatory region sequence-specific DNA binding Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. go-plus.json RNA polymerase II regulatory region DNA binding http://purl.obolibrary.org/obo/GO_0000977 GO:0048919 biolink:BiologicalProcess posterior lateral line neuromast development The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. go-plus.json http://purl.obolibrary.org/obo/GO_0048919 GO:0000978 biolink:MolecularActivity RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. go-plus.json RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II promoter proximal region sequence-specific DNA binding|RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0000978 CHEBI:72344 biolink:ChemicalSubstance alpha-D-kanosamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72344 chebi_ph7_3 CHEBI:23377 biolink:ChemicalSubstance copper molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_23377 CHEBI:23378 biolink:ChemicalSubstance copper cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_23378 chebi_ph7_3 GO:0000940 biolink:CellularComponent outer kinetochore The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions. go-plus.json condensed chromosome outer kinetochore|condensed nuclear chromosome outer kinetochore|outer kinetochore plate|outer kinetochore of condensed chromosome|outer kinetochore of condensed nuclear chromosome http://purl.obolibrary.org/obo/GO_0000940 CHEBI:72346 biolink:ChemicalSubstance roseoflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72346 CHEBI:23375 biolink:ChemicalSubstance copalyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23375 GO:0000941 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000941 GO:0048920 biolink:BiologicalProcess posterior lateral line neuromast primordium migration The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop. go-plus.json PLL neuromast primordium migration http://purl.obolibrary.org/obo/GO_0048920 GO:0048921 biolink:BiologicalProcess posterior lateral line neuromast cupula development The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter. go-plus.json http://purl.obolibrary.org/obo/GO_0048921 GO:0048922 biolink:BiologicalProcess posterior lateral line neuromast deposition The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line. go-plus.json http://purl.obolibrary.org/obo/GO_0048922 GO:0048923 biolink:BiologicalProcess posterior lateral line neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0048923 UBERON:0014720 biolink:AnatomicalEntity interlobar duct A duct that is located between lobes, within conspicuous, thick connective tissue septa that separate lobes. All interlobar ducts are excretory. go-plus.json intralobular ductule http://purl.obolibrary.org/obo/UBERON_0014720 CHEBI:86990 biolink:ChemicalSubstance N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86990 CHEBI:86991 biolink:ChemicalSubstance (R)-fluoxetine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86991 UBERON:6005434 biolink:AnatomicalEntity insect visual anlage go-plus.json A VisSys|AVis http://purl.obolibrary.org/obo/UBERON_6005434 CHEBI:86992 biolink:ChemicalSubstance (S)-fluoxetine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86992 CHEBI:86993 biolink:ChemicalSubstance (R)-fluoxetine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86993 chebi_ph7_3 CHEBI:86994 biolink:ChemicalSubstance carboxyphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86994 chebi_ph7_3 CHEBI:86995 biolink:ChemicalSubstance (S)-fluoxetine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86995 chebi_ph7_3 UBERON:0014717 biolink:AnatomicalEntity mucous acinus The secretory unit of a mucous gland. The acinar portion is composed of mucous secreting cells. go-plus.json acinus of mucuous gland|mucus acinus http://purl.obolibrary.org/obo/UBERON_0014717 UBERON:0014719 biolink:AnatomicalEntity intralobular duct A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular go-plus.json intralobular ductule http://purl.obolibrary.org/obo/UBERON_0014719 CHEBI:86999 biolink:ChemicalSubstance 1-acyl-2-palmitoylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_86999 chebi_ph7_3 UBERON:0014716 biolink:AnatomicalEntity interlobular duct A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014716 GO:0048924 biolink:BiologicalProcess posterior lateral line neuromast mantle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0048924 GO:0000946 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000946 GO:0000947 biolink:BiologicalProcess amino acid catabolic process to alcohol via Ehrlich pathway The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. go-plus.json http://purl.obolibrary.org/obo/GO_0000947 GO:0048925 biolink:BiologicalProcess lateral line system development The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear. go-plus.json http://purl.obolibrary.org/obo/GO_0048925 GO:0048926 biolink:BiologicalProcess electrosensory lateral line system development The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048926 GO:0000948 biolink:BiologicalProcess amino acid catabolic process to carboxylic acid via Ehrlich pathway The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0000948 GO:0048927 biolink:BiologicalProcess posterior lateral line neuromast support cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048927 GO:0000949 biolink:BiologicalProcess aromatic amino acid family catabolic process to alcohol via Ehrlich pathway The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. go-plus.json http://purl.obolibrary.org/obo/GO_0000949 GO:0048928 biolink:BiologicalProcess posterior lateral line ganglion neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion. go-plus.json http://purl.obolibrary.org/obo/GO_0048928 GO:0000942 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000942 GO:0048929 biolink:BiologicalProcess efferent axon development in posterior lateral line nerve The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048929 GO:0000943 biolink:CellularComponent retrotransposon nucleocapsid A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog. Wikipedia:Virus-like_particle go-plus.json VLP|Virus-like particle http://purl.obolibrary.org/obo/GO_0000943 GO:0000944 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000944 GO:0000945 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000945 CHEBI:72343 biolink:ChemicalSubstance alpha-D-kanosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72343 CHEBI:23388 biolink:ChemicalSubstance coproporphyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23388 CHEBI:23389 biolink:ChemicalSubstance cobalt-corrinoid heptacarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23389 GO:0000950 biolink:BiologicalProcess branched-chain amino acid catabolic process to alcohol via Ehrlich pathway The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. go-plus.json branched chain family amino acid catabolic process to alcohol via Ehrlich pathway http://purl.obolibrary.org/obo/GO_0000950 GO:0000951 biolink:BiologicalProcess methionine catabolic process to 3-methylthiopropanol The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. go-plus.json http://purl.obolibrary.org/obo/GO_0000951 GO:0048930 biolink:BiologicalProcess glial cell migration in posterior lateral line nerve The movement of a glial cell along the axons in the posterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048930 GO:0000952 biolink:BiologicalProcess aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0000952 GO:0048931 biolink:BiologicalProcess posterior lateral line nerve glial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048931 GO:0048932 biolink:BiologicalProcess myelination of posterior lateral line nerve axons The formation of compact myelin sheaths around the axons of the posterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048932 GO:0048933 biolink:BiologicalProcess afferent axon development in posterior lateral line nerve The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048933 GO:0048934 biolink:BiologicalProcess peripheral nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0048934 CHEBI:86980 biolink:ChemicalSubstance diacylglycerol 36:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_86980 chebi_ph7_3 CHEBI:86982 biolink:ChemicalSubstance (2R)-2,6-dimethylheptanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86982 chebi_ph7_3 CHEBI:86983 biolink:ChemicalSubstance (2S)-2,6-dimethylheptanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_86983 chebi_ph7_3 UBERON:0014706 biolink:AnatomicalEntity primitive renal collecting duct system go-plus.json metanephros primitive collecting ducts|primitive collecting duct http://purl.obolibrary.org/obo/UBERON_0014706 CHEBI:86987 biolink:ChemicalSubstance diacylglycerol 36:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_86987 chebi_ph7_3 UBERON:0014702 biolink:AnatomicalEntity frontonasal process epithelium A epithelium that is part of a frontonasal prominence. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014702 UBERON:0014703 biolink:AnatomicalEntity anal membrane ectodermal component A unilaminar epithelium that develops_from a ectoderm and is part of a anal region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014703 UBERON:0014704 biolink:AnatomicalEntity pleuroperitoneal canal lumen A anatomical space that is enclosed by a pleuroperitoneal canal. go-plus.json pleuro-peritoneal canal cavity http://purl.obolibrary.org/obo/UBERON_0014704 UBERON:0014705 biolink:AnatomicalEntity median lingual swelling epithelium A epithelium that is part of a median lingual swelling. go-plus.json tuberculum impar epitheilium http://purl.obolibrary.org/obo/UBERON_0014705 GO:0000957 biolink:BiologicalProcess mitochondrial RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0000957 GO:0048935 biolink:BiologicalProcess peripheral nervous system neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0048935 GO:0000958 biolink:BiologicalProcess mitochondrial mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0000958 GO:0048936 biolink:BiologicalProcess peripheral nervous system neuron axonogenesis Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048936 GO:0048937 biolink:BiologicalProcess lateral line nerve glial cell development The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048937 GO:0000959 biolink:BiologicalProcess mitochondrial RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0000959 GO:0048938 biolink:BiologicalProcess lateral line nerve glial cell morphogenesis involved in differentiation The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048938 GO:0048939 biolink:BiologicalProcess anterior lateral line nerve glial cell development The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048939 GO:0000953 biolink:BiologicalProcess branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. go-plus.json branched chain family amino acid catabolic process to carboxylic acid via Ehrlich pathway http://purl.obolibrary.org/obo/GO_0000953 GO:0000954 biolink:BiologicalProcess methionine catabolic process to 3-methylthiopropanoate The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0000954 GO:0000955 biolink:BiologicalProcess amino acid catabolic process via Ehrlich pathway The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols. go-plus.json http://purl.obolibrary.org/obo/GO_0000955 GO:0000956 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. go-plus.json nuclear mRNA catabolism|nuclear mRNA degradation|nuclear mRNA breakdown http://purl.obolibrary.org/obo/GO_0000956 CHEBI:23356 biolink:ChemicalSubstance S-substituted coenzyme M go-plus.json http://purl.obolibrary.org/obo/CHEBI_23356 GO:0048940 biolink:BiologicalProcess anterior lateral line nerve glial cell morphogenesis involved in differentiation The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048940 GO:0048941 biolink:BiologicalProcess posterior lateral line nerve glial cell development The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048941 CHEBI:23354 biolink:ChemicalSubstance coenzyme go-plus.json http://purl.obolibrary.org/obo/CHEBI_23354 GO:0048942 biolink:BiologicalProcess posterior lateral line nerve glial cell morphogenesis involved in differentiation The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048942 CHEBI:23357 biolink:ChemicalSubstance cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_23357 UBERON:0014783 biolink:AnatomicalEntity cloacal muscle Any muscle organ that is part of a cloaca. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014783 UBERON:6005413 biolink:AnatomicalEntity insect anlage in statu nascendi "anlagen in statu nascendi" are domains that do not yet coincide 1:1 with a later organ. Anlagen in statu nascendi are typically defined for the early blastoderm by the expression domains of genes which, in the late blastoderm or later, are expressed in specific anlagen, but initially come on in larger domains. go-plus.json A0 http://purl.obolibrary.org/obo/UBERON_6005413 CHEBI:37996 biolink:ChemicalSubstance organic thiosulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37996 CHEBI:37997 biolink:ChemicalSubstance homopolymer macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_37997 GO:0000928 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000928 GO:0000929 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000929 CHEBI:37998 biolink:ChemicalSubstance glycolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37998 GO:0000924 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000924 GO:0000925 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000925 GO:0000926 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000926 GO:0000927 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000927 GO:0000920 biolink:BiologicalProcess septum digestion after cytokinesis The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. go-plus.json cell separation following cytokinesis|mitotic cytokinetic cell separation|cell separation after cytokinesis|cytokinetic cell separation|daughter cell separation http://purl.obolibrary.org/obo/GO_0000920 GO:0000921 biolink:BiologicalProcess septin ring assembly The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex. go-plus.json septin assembly and septum biosynthesis|septin assembly and septum formation http://purl.obolibrary.org/obo/GO_0000921 GO:0000922 biolink:CellularComponent spindle pole Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0000922 GO:0000923 biolink:CellularComponent equatorial microtubule organizing center A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis. go-plus.json equatorial microtubule organising centre|EMTOC http://purl.obolibrary.org/obo/GO_0000923 CHEBI:23366 biolink:ChemicalSubstance compatible osmolytes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23366 CHEBI:23367 biolink:ChemicalSubstance molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_23367 GO:0000930 biolink:CellularComponent gamma-tubulin complex A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species. go-plus.json http://purl.obolibrary.org/obo/GO_0000930 goslim_pir UBERON:0014770 biolink:AnatomicalEntity palpebral artery An artery that supplies blood to an eyelid. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014770 UBERON:0000127 biolink:AnatomicalEntity facial nucleus the group of motor neurons residing in the pons that innervate the muscles of facial expression go-plus.json facial nerve nucleus|facial VII motor nucleus|facial VII nucleus|nucleus of facial nerve http://purl.obolibrary.org/obo/UBERON_0000127 UBERON:0000128 biolink:AnatomicalEntity olivary body prominent oval structure in the medulla oblongata, present in pairs, the lower portion of the brainstem. They contain the olivary nuclei go-plus.json olivary nucleus|olive body|olive|oliva http://purl.obolibrary.org/obo/UBERON_0000128 UBERON:0014775 biolink:AnatomicalEntity prosomere A neuromere that is part of the presumptive forebrain go-plus.json future prosencephalon|forebrain segment|forebrain neuromere|segment of forebrain http://purl.obolibrary.org/obo/UBERON_0014775 UBERON:0014776 biolink:AnatomicalEntity midbrain neuromere A neuromere that is part of the presumptive midbrain go-plus.json neuromere of mesomere group|future mesencephalon|mesomere of nervous system|segment of midbrain|mesomere group|midbrain segment|mesomere http://purl.obolibrary.org/obo/UBERON_0014776 UBERON:0014777 biolink:AnatomicalEntity spinal neuromere A neuromere that is part of the presumptive spinal cord go-plus.json spinal neuromeres|spinal cord segment|spinal cord metameric segment http://purl.obolibrary.org/obo/UBERON_0014777 CHEBI:23360 biolink:ChemicalSubstance colitose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23360 chebi_ph7_3 UBERON:6005425 biolink:AnatomicalEntity insect visual anlage in statu nascendi go-plus.json Asn VisSys|A0Vis http://purl.obolibrary.org/obo/UBERON_6005425 GO:0000939 biolink:CellularComponent inner kinetochore The region of a kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome. go-plus.json inner centromere core complex|condensed nuclear chromosome inner kinetochore|inner kinetochore plate|inner kinetochore of condensed chromosome|inner kinetochore of condensed nuclear chromosome|condensed chromosome inner kinetochore http://purl.obolibrary.org/obo/GO_0000939 UBERON:0014769 biolink:AnatomicalEntity palpebral vein A blood vessel that drains from from an eyelid. go-plus.json venae palpebrales|palpebral veins http://purl.obolibrary.org/obo/UBERON_0014769 GO:0000935 biolink:CellularComponent division septum A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments. go-plus.json complete septum|cell septum surface|divison septum|septum surface http://purl.obolibrary.org/obo/GO_0000935 GO:0000936 biolink:CellularComponent primary cell septum A cell septum that forms following nuclear division. go-plus.json primary septum http://purl.obolibrary.org/obo/GO_0000936 GO:0000937 biolink:CellularComponent dolipore septum A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome). go-plus.json http://purl.obolibrary.org/obo/GO_0000937 GO:0000938 biolink:CellularComponent GARP complex A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles. go-plus.json Golgi associated retrograde protein complex|VFT tethering complex|Vps fifty three tethering complex http://purl.obolibrary.org/obo/GO_0000938 GO:0000931 biolink:CellularComponent gamma-tubulin large complex A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe. go-plus.json gamma-tubulin large complex, mitotic spindle pole body|gamma-tubulin large complex, interphase microtubule organizing centre|gamma-tubulin large complex, centrosomal|gamma-tubulin large complex, interphase microtubule organizing center|gamma-tubulin ring complex, centrosomal|gamma-tubulin large complex, equatorial microtubule organizing centre|gamma-tubulin large complex, equatorial microtubule organizing center|gamma-tubulin large complex, spindle pole body|gamma-tubulin large complex, iMTOC|gamma-tubulin large complex, eMTOC|gamma-tubulin ring complex http://purl.obolibrary.org/obo/GO_0000931 GO:0000932 biolink:CellularComponent P-body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing. Wikipedia:P_body go-plus.json cytoplasmic foci|cytoplasmic mRNA processing body|P body http://purl.obolibrary.org/obo/GO_0000932 GO:0000933 biolink:CellularComponent adventitious septum A cell septum whose formation is independent of nuclear division. go-plus.json http://purl.obolibrary.org/obo/GO_0000933 GO:0000934 biolink:CellularComponent porous cell septum A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments. go-plus.json porous septum http://purl.obolibrary.org/obo/GO_0000934 CHEBI:72388 biolink:ChemicalSubstance lysophosphatidylethanolamine zwitterion 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72388 chebi_ph7_3 CHEBI:23333 biolink:ChemicalSubstance cob(III)alamins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23333 CHEBI:72389 biolink:ChemicalSubstance lysophosphatidylethanolamine zwitterion 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72389 chebi_ph7_3 CHEBI:23334 biolink:ChemicalSubstance cobalamins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23334 UBERON:0000116 biolink:AnatomicalEntity lung saccule Primitive gas exchange portion of the lung composed of type I and type II cells[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000116 UBERON:0000117 biolink:AnatomicalEntity respiratory tube A tube in the respiratory system. Examples: bronchus, bronchiole, trachea. go-plus.json airway|segment of tracheobronchial tree|respiratory conducting tube|segment of tracheobronchial tree|tracheobronchial tree segment http://purl.obolibrary.org/obo/UBERON_0000117 UBERON:0000118 biolink:AnatomicalEntity lung bud Structure derived from foregut that becomes a lung[GO]. go-plus.json gemma respiratoria|gemma pulmonalis|respiratory diverticulum|lung bud|primary lung bud http://purl.obolibrary.org/obo/UBERON_0000118 UBERON:0000119 biolink:AnatomicalEntity cell layer Portion of tissue, that consists of single layer of cells connected to each other by cell junctions. Examples: layer of glial cells; epithelium. go-plus.json sheath of cells|cell sheath|layer of cells|layer http://purl.obolibrary.org/obo/UBERON_0000119 CHEBI:23336 biolink:ChemicalSubstance cobalt cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_23336 UBERON:0014764 biolink:AnatomicalEntity anatomical line along groove Anatomical line that delineates a furrow or depression in an organ or tissue. go-plus.json groove|line delineating groove http://purl.obolibrary.org/obo/UBERON_0014764 UBERON:0014765 biolink:AnatomicalEntity crus of diaphragm The domain of the diaphragm that is located dorsally and attaches to the vertebrae and surrounds the esophagus and aorta. go-plus.json crus of the diaphragm|diaphragm crura|crura of the diaphragm|diaphragmatic crura|crural diaphragm http://purl.obolibrary.org/obo/UBERON_0014765 UBERON:0014766 biolink:AnatomicalEntity right crus of diaphragm A crus of diaphragm that is in_the_right_side_of a diaphragm. go-plus.json crus dextrum diaphragmatis|external sphincter of esophagus|right crus of lumbar part of diaphragm|crus dextrum (Diaphragma)|right crus of diaphragm http://purl.obolibrary.org/obo/UBERON_0014766 UBERON:0014767 biolink:AnatomicalEntity left crus of diaphragm A crus of diaphragm that is in_the_left_side_of a diaphragm. go-plus.json left crus of diaphragm|crus sinistrum diaphragmatis|left crus of lumbar part of diaphragm|crus sinistrum (Diaphragma) http://purl.obolibrary.org/obo/UBERON_0014767 GO:0000906 biolink:MolecularActivity 6,7-dimethyl-8-ribityllumazine synthase activity Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate. RHEA:26152|EC:2.5.1.78|MetaCyc:LUMAZINESYN-RXN go-plus.json lumazine synthase activity http://purl.obolibrary.org/obo/GO_0000906 GO:0000907 biolink:MolecularActivity sulfonate dioxygenase activity Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2. go-plus.json sulfonate/alpha-ketoglutarate dioxygenase activity|sulphonate dioxygenase activity http://purl.obolibrary.org/obo/GO_0000907 GO:0000908 biolink:MolecularActivity taurine dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite. EC:1.14.11.17|MetaCyc:RXN0-299|RHEA:15909|KEGG_REACTION:R05320 go-plus.json taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)|2-aminoethanesulfonate dioxygenase activity|alpha-ketoglutarate-dependent taurine dioxygenase activity http://purl.obolibrary.org/obo/GO_0000908 GO:0000909 biolink:BiologicalProcess sporocarp development involved in sexual reproduction The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi. go-plus.json perfect stage fruiting body development|fruiting body development involved in sexual reproduction|ascus development|fruiting body formation involved in sexual reproduction http://purl.obolibrary.org/obo/GO_0000909 GO:0000902 biolink:BiologicalProcess cell morphogenesis The developmental process in which the size or shape of a cell is generated and organized. go-plus.json cellular morphogenesis http://purl.obolibrary.org/obo/GO_0000902 goslim_generic|goslim_chembl|goslim_yeast|goslim_drosophila CHEBI:72381 biolink:ChemicalSubstance lysophosphatidylethanolamine zwitterion 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72381 chebi_ph7_3 GO:0000903 biolink:BiologicalProcess obsolete regulation of cell shape during vegetative growth phase OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods. go-plus.json cell morphogenesis during vegetative growth phase|regulation of cell morphogenesis during vegetative growth phase|cellular morphogenesis during vegetative growth http://purl.obolibrary.org/obo/GO_0000903 GO:0000904 biolink:BiologicalProcess cell morphogenesis involved in differentiation The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. go-plus.json http://purl.obolibrary.org/obo/GO_0000904 UBERON:0000125 biolink:AnatomicalEntity neural nucleus A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO) go-plus.json nervous system nucleus|nucleus of neuraxis|nucleus of CNS|nucleus|neuraxis nucleus|neuronal nucleus http://purl.obolibrary.org/obo/UBERON_0000125 GO:0000905 biolink:BiologicalProcess sporocarp development involved in asexual reproduction The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction. go-plus.json fruiting body formation involved in asexual reproduction|imperfect stage fruiting body development|haploid fruiting|monokaryotic fruiting|conidium development|homokaryotic fruiting http://purl.obolibrary.org/obo/GO_0000905 UBERON:0000126 biolink:AnatomicalEntity cranial nerve nucleus Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves go-plus.json nucleus of cranial nerve|nucleus nervi cranialis|cranial neural nucleus http://purl.obolibrary.org/obo/UBERON_0000126 CHEBI:72384 biolink:ChemicalSubstance lysophosphatidylethanolamine zwitterion 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72384 chebi_ph7_3 UBERON:0000120 biolink:AnatomicalEntity blood brain barrier Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions. go-plus.json BBB|blood-brain barrier http://purl.obolibrary.org/obo/UBERON_0000120 GO:0000900 biolink:MolecularActivity translation repressor activity, mRNA regulatory element binding Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid. go-plus.json translation repressor activity, nucleic acid binding http://purl.obolibrary.org/obo/GO_0000900 UBERON:0000122 biolink:AnatomicalEntity neuron projection bundle A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. go-plus.json funiculus|nerve fiber bundle|neural fiber bundle http://purl.obolibrary.org/obo/UBERON_0000122 CHEBI:72387 biolink:ChemicalSubstance lysophosphatidylethanolamine zwitterion 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72387 chebi_ph7_3 GO:0000901 biolink:MolecularActivity translation repressor activity, non-nucleic acid binding Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0000901 UBERON:0000109 biolink:AnatomicalEntity gastrula stage A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. go-plus.json trilaminar disk stage|trilaminar germ stage|blastocystis trilaminaris stage|trilaminar blastoderm stage|trilaminar blastocyst stage|trilaminar stage http://purl.obolibrary.org/obo/UBERON_0000109 GO:1902807 biolink:BiologicalProcess negative regulation of cell cycle G1/S phase transition Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. go-plus.json down-regulation of cell cycle G1/S phase transition|downregulation of cell cycle G1/S phase transition|down regulation of cell cycle G1/S phase transition|inhibition of cell cycle G1/S phase transition http://purl.obolibrary.org/obo/GO_1902807 GO:1902808 biolink:BiologicalProcess positive regulation of cell cycle G1/S phase transition Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. go-plus.json up-regulation of cell cycle G1/S phase transition|activation of cell cycle G1/S phase transition|up regulation of cell cycle G1/S phase transition|upregulation of cell cycle G1/S phase transition http://purl.obolibrary.org/obo/GO_1902808 CHEBI:23345 biolink:ChemicalSubstance cobyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23345 GO:1902805 biolink:BiologicalProcess positive regulation of synaptic vesicle transport Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport. go-plus.json activation of synaptic vesicle transport|up-regulation of synaptic vesicle transport|upregulation of synaptic vesicle fission|up regulation of synaptic vesicle fusion|positive regulation of synaptic vesicle fusion|up-regulation of synaptic vesicle fission|activation of synaptic vesicle fusion|up regulation of synaptic vesicle transport|activation of synaptic vesicle fission|up-regulation of synaptic vesicle fusion|positive regulation of synaptic vesicle fission|up regulation of synaptic vesicle fission|upregulation of synaptic vesicle transport|upregulation of synaptic vesicle fusion http://purl.obolibrary.org/obo/GO_1902805 GO:1902806 biolink:BiologicalProcess regulation of cell cycle G1/S phase transition Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1902806 GO:1902803 biolink:BiologicalProcess regulation of synaptic vesicle transport Any process that modulates the frequency, rate or extent of synaptic vesicle transport. go-plus.json regulation of synaptic vesicle fission|regulation of synaptic vesicle fusion http://purl.obolibrary.org/obo/GO_1902803 UBERON:0000105 biolink:AnatomicalEntity life cycle stage A spatiotemporal region encompassing some part of the life cycle of an organism. go-plus.json developmental stage|stage http://purl.obolibrary.org/obo/UBERON_0000105 UBERON:0000106 biolink:AnatomicalEntity zygote stage A stage at which the organism is a single cell produced by means of sexual reproduction. go-plus.json zygote|fertilized egg stage|one-cell stage|zygotum|1-cell stage|one cell stage|fertilized egg stage http://purl.obolibrary.org/obo/UBERON_0000106 GO:1902804 biolink:BiologicalProcess negative regulation of synaptic vesicle transport Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport. go-plus.json inhibition of synaptic vesicle fission|down-regulation of synaptic vesicle transport|down-regulation of synaptic vesicle fusion|negative regulation of synaptic vesicle fusion|negative regulation of synaptic vesicle fission|down-regulation of synaptic vesicle fission|downregulation of synaptic vesicle transport|down regulation of synaptic vesicle transport|inhibition of synaptic vesicle fusion|inhibition of synaptic vesicle transport|downregulation of synaptic vesicle fission|down regulation of synaptic vesicle fusion|down regulation of synaptic vesicle fission|downregulation of synaptic vesicle fusion http://purl.obolibrary.org/obo/GO_1902804 GO:1902801 biolink:BiologicalProcess regulation of heterochromatin island assembly Any process that modulates the frequency, rate or extent of heterochromatin island assembly. go-plus.json regulation of heterochromatin island formation http://purl.obolibrary.org/obo/GO_1902801 UBERON:0000107 biolink:AnatomicalEntity cleavage stage The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000107 GO:1902802 biolink:BiologicalProcess regulation of heterochromatin domain assembly Any process that modulates the frequency, rate or extent of heterochromatin domain assembly. go-plus.json regulation of HOOD assembly|regulation of heterochromatin domain formation|regulation of HOOD formation http://purl.obolibrary.org/obo/GO_1902802 UBERON:0000108 biolink:AnatomicalEntity blastula stage An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000108 CHEBI:23347 biolink:ChemicalSubstance coclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23347 GO:1902800 biolink:BiologicalProcess positive regulation of phosphodiesterase I activity Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity. go-plus.json positive regulation of 5'-nucleotide phosphodiesterase activity|up-regulation of oligonucleate 5'-nucleotidohydrolase activity|activation of PDE I activity|upregulation of 5'-PDase activity|positive regulation of 5'-NPDase activity|up regulation of 5'-nucleotide phosphodiesterase activity|upregulation of 5'-phosphodiesterase activity|activation of 5'NPDE activity|up regulation of 5'-NPDase activity|activation of alkaline phosphodiesterase activity|upregulation of exonuclease I activity|activation of 5'-PDE activity|upregulation of phosphodiesterase I activity|up regulation of 5'-exonuclease activity|upregulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up regulation of orthophosphoric diester phosphohydrolase activity|positive regulation of 5'-exonuclease activity|upregulation of nucleotide pyrophosphatase/phosphodiesterase I activity|positive regulation of orthophosphoric diester phosphohydrolase activity|activation of orthophosphoric diester phosphohydrolase activity|up-regulation of alkaline phosphodiesterase activity|up-regulation of 5'NPDE activity|upregulation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of PDE I activity|up-regulation of 5'-PDE activity|up regulation of 5'-PDase activity|up regulation of PDE I activity|up regulation of 5'-phosphodiesterase activity|upregulation of 5'-nucleotide phosphodiesterase activity|positive regulation of 5'-PDase activity|up-regulation of exonuclease I activity|upregulation of 5'-NPDase activity|activation of 5'-exonuclease activity|up-regulation of phosphodiesterase I activity|positive regulation of 5'-phosphodiesterase activity|activation of phosphodiesterase I activity|up regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|upregulation of alkaline phosphodiesterase activity|activation of 5'-PDase activity|upregulation of 5'NPDE activity|activation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|positive regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|activation of exonuclease I activity|up-regulation of 5'-exonuclease activity|activation of 5'-phosphodiesterase activity|up regulation of oligonucleate 5'-nucleotidohydrolase activity|upregulation of 5'-PDE activity|positive regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|activation of nucleotide pyrophosphatase/phosphodiesterase I activity|up-regulation of orthophosphoric diester phosphohydrolase activity|activation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of oligonucleate 5'-nucleotidohydrolase activity|up-regulation of 5'-nucleotide phosphodiesterase activity|up-regulation of 5'-NPDase activity|upregulation of PDE I activity|positive regulation of exonuclease I activity|up-regulation of 5'-PDase activity|up-regulation of 5'-phosphodiesterase activity|up regulation of exonuclease I activity|activation of 5'-nucleotide phosphodiesterase activity|up regulation of phosphodiesterase I activity|up regulation of alkaline phosphodiesterase activity|activation of 5'-NPDase activity|up regulation of 5'NPDE activity|upregulation of 5'-exonuclease activity|upregulation of orthophosphoric diester phosphohydrolase activity|up regulation of 5'-PDE activity|positive regulation of 5'NPDE activity|up-regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|positive regulation of alkaline phosphodiesterase activity|positive regulation of 5'-PDE activity|up-regulation of PDE I activity|up-regulation of nucleotide pyrophosphatase/phosphodiesterase I activity http://purl.obolibrary.org/obo/GO_1902800 CHEBI:23341 biolink:ChemicalSubstance cobamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_23341 CHEBI:37986 biolink:ChemicalSubstance 1-(3-O-sulfo-beta-D-galactosyl-(1->4)-beta-D-glucosyl)-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37986 GO:0000917 biolink:BiologicalProcess division septum assembly The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material. go-plus.json division septum formation|division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle|septin assembly and septum formation involved in mitotic cell cycle|septin assembly and septum biosynthesis involved in mitotic cell cycle|formation of division septum|formation of division septum involved in mitotic cell cycle|division septum assembly involved in cell cycle cytokinesis|septin assembly and septum biosynthesis|division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle|septin assembly and septum formation|division septum formation involved in mitotic cell cycle|division septum formation involved in cell cycle cytokinesis|septation|mitotic division septum assembly http://purl.obolibrary.org/obo/GO_0000917 GO:0000918 biolink:BiologicalProcess division septum site selection The process of marking the site where a division septum will form. go-plus.json septin assembly and septum formation|septum positioning|selection of site for barrier cell septum biosynthesis|selection of site for barrier cell septum formation|selection of site for division septum formation|septin assembly and septum biosynthesis http://purl.obolibrary.org/obo/GO_0000918 GO:0000919 biolink:BiologicalProcess cell plate assembly The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast. go-plus.json cell plate formation http://purl.obolibrary.org/obo/GO_0000919 UBERON:0000112 biolink:AnatomicalEntity sexually immature stage go-plus.json subadult stage|juvenile stage|immature stage http://purl.obolibrary.org/obo/UBERON_0000112 GO:0000913 biolink:BiologicalProcess preprophase band assembly The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation. go-plus.json preprophase band formation http://purl.obolibrary.org/obo/GO_0000913 GO:0000914 biolink:BiologicalProcess phragmoplast assembly The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles). go-plus.json phragmoplast formation http://purl.obolibrary.org/obo/GO_0000914 UBERON:0000113 biolink:AnatomicalEntity post-juvenile adult stage The stage of being a sexually mature adult animal. go-plus.json adult stage http://purl.obolibrary.org/obo/UBERON_0000113 GO:0000915 biolink:BiologicalProcess actomyosin contractile ring assembly The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis. go-plus.json cytokinesis, actomyosin contractile ring assembly|cytokinesis, actomyosin contractile ring formation|cytokinesis, actomyosin ring formation|constriction ring assembly|contractile ring assembly|cytokinesis, actomyosin ring biosynthesis|cytokinesis, contractile ring assembly http://purl.obolibrary.org/obo/GO_0000915 UBERON:0000114 biolink:AnatomicalEntity lung connective tissue the connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin go-plus.json pulmonary interstitial tissue|lung interstitial tissue|pulmonary interstitium|pulmonary connective tissue|lung interstitium|connective tissue of lung http://purl.obolibrary.org/obo/UBERON_0000114 GO:0000916 biolink:BiologicalProcess actomyosin contractile ring contraction The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle. go-plus.json cytokinesis, actomyosin ring contraction|actomyosin contractile ring constriction|cytokinesis, contractile ring contraction|contractile ring contraction involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_0000916 UBERON:0000115 biolink:AnatomicalEntity lung epithelium The epithelial layer of the lung. go-plus.json pulmonary epithelium|epithelial tissue of lung|epithelium of lung|lung epithelial tissue http://purl.obolibrary.org/obo/UBERON_0000115 GO:0000910 biolink:BiologicalProcess cytokinesis The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells. Wikipedia:Cytokinesis go-plus.json cell cycle cytokinesis|cytokinesis involved in cell cycle http://purl.obolibrary.org/obo/GO_0000910 goslim_yeast|goslim_candida|gocheck_do_not_manually_annotate|goslim_aspergillus GO:0000911 biolink:BiologicalProcess cytokinesis by cell plate formation The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0000911 GO:1902809 biolink:BiologicalProcess regulation of skeletal muscle fiber differentiation Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1902809 UBERON:0000110 biolink:AnatomicalEntity neurula stage Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0000110 GO:0000912 biolink:BiologicalProcess assembly of actomyosin apparatus involved in cytokinesis The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis. go-plus.json cytokinesis, formation of actomyosin apparatus|actomyosin apparatus assembly involved in cytokinesis|formation of actomyosin apparatus involved in cytokinesis http://purl.obolibrary.org/obo/GO_0000912 UBERON:0000111 biolink:AnatomicalEntity organogenesis stage A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. go-plus.json segmentation stage http://purl.obolibrary.org/obo/UBERON_0000111 GO:0034338 biolink:MolecularActivity short-chain carboxylesterase activity Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms. go-plus.json butyrate esterase activity|propionyl esterase activity|methylbutyrate esterase activity|butyryl esterase activity|methylbutyrase activity|monobutyrase activity|short-chain esterase activity http://purl.obolibrary.org/obo/GO_0034338 GO:0034339 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor http://purl.obolibrary.org/obo/GO_0034339 GO:0010369 biolink:CellularComponent chromocenter A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure. go-plus.json http://purl.obolibrary.org/obo/GO_0010369 GO:0009380 biolink:CellularComponent excinuclease repair complex Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap. go-plus.json excinuclease ABC complex|UvrABC excinuclease complex http://purl.obolibrary.org/obo/GO_0009380 GO:0009381 biolink:MolecularActivity excinuclease ABC activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind. go-plus.json http://purl.obolibrary.org/obo/GO_0009381 GO:0009382 biolink:CellularComponent imidazoleglycerol-phosphate synthase complex Complex that possesses imidazoleglycerol-phosphate synthase activity. go-plus.json imidazoleglycerol phosphate synthase complex http://purl.obolibrary.org/obo/GO_0009382 GO:0009383 biolink:MolecularActivity rRNA (cytosine-C5-)-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA. Reactome:R-HSA-6793057|Reactome:R-HSA-6790944 go-plus.json rRNA (cytosine-C5-967)-methyltransferase activity|rRNA m5C967 methyltransferase activity http://purl.obolibrary.org/obo/GO_0009383 GO:0009384 biolink:MolecularActivity N-acylmannosamine kinase activity Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate. EC:2.7.1.60|Reactome:R-HSA-4085028|MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN|Reactome:R-HSA-4088322|RHEA:23832 go-plus.json acylmannosamine kinase (phosphorylating)|ATP:N-acetylmannosamine 6-phosphotransferase activity|N-acyl-D-mannosamine kinase activity|N-acetylmannosamine kinase activity|acetylmannosamine kinase activity|ATP:N-acyl-D-mannosamine 6-phosphotransferase activity|acetylamidodeoxymannokinase activity|acylaminodeoxymannokinase activity|acylmannosamine kinase activity http://purl.obolibrary.org/obo/GO_0009384 GO:0034330 biolink:BiologicalProcess cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. go-plus.json cell junction biogenesis|cell junction organisation|cell junction assembly and maintenance http://purl.obolibrary.org/obo/GO_0034330 goslim_generic|goslim_chembl GO:0009374 biolink:MolecularActivity biotin binding Binding to biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. go-plus.json vitamin H binding|vitamin B7 binding http://purl.obolibrary.org/obo/GO_0009374 GO:0010363 biolink:BiologicalProcess regulation of plant-type hypersensitive response Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response. go-plus.json regulation of plant hypersensitive response|regulation of HR-PCD|regulation of HR http://purl.obolibrary.org/obo/GO_0010363 GO:0034331 biolink:BiologicalProcess cell junction maintenance The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0034331 GO:0009375 biolink:CellularComponent ferredoxin hydrogenase complex An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances. go-plus.json hydrogenase complex http://purl.obolibrary.org/obo/GO_0009375 CHEBI:62920 biolink:ChemicalSubstance icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62920 chebi_ph7_3 GO:0010364 biolink:BiologicalProcess regulation of ethylene biosynthetic process Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0010364 GO:0010361 biolink:BiologicalProcess regulation of anion channel activity by blue light Any process in which blue light modulates the frequency, rate or extent of anion channel activity. go-plus.json regulation by blue light of anion channel activity http://purl.obolibrary.org/obo/GO_0010361 GO:0009376 biolink:CellularComponent HslUV protease complex A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. go-plus.json ClpYQ protease complex http://purl.obolibrary.org/obo/GO_0009376 GO:0034332 biolink:BiologicalProcess adherens junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json adherens junction organisation http://purl.obolibrary.org/obo/GO_0034332 GO:0010362 biolink:BiologicalProcess negative regulation of anion channel activity by blue light Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity. go-plus.json inhibition by blue light of anion channel activity|negative regulation by blue light of anion channel activity http://purl.obolibrary.org/obo/GO_0010362 GO:0034333 biolink:BiologicalProcess adherens junction assembly The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json adherens junction formation http://purl.obolibrary.org/obo/GO_0034333 GO:0009377 biolink:MolecularActivity obsolete HslUV protease activity OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins. go-plus.json HslUV protease activity http://purl.obolibrary.org/obo/GO_0009377 GO:0034334 biolink:BiologicalProcess adherens junction maintenance The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0034334 GO:0009378 biolink:MolecularActivity four-way junction helicase activity Unwinding a DNA helix of DNA containing four-way junctions, including Holliday junctions, driven by ATP hydrolysis. go-plus.json ATP-dependent four-way junction helicase activity|ATP-dependent four-way junction DNA helicase activity|ATP-dependent Holliday junction helicase activity|Holliday junction helicase activity http://purl.obolibrary.org/obo/GO_0009378 CHEBI:62923 biolink:ChemicalSubstance 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62923 GO:0010367 biolink:CellularComponent extracellular isoamylase complex A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space. go-plus.json http://purl.obolibrary.org/obo/GO_0010367 GO:0010368 biolink:CellularComponent chloroplast isoamylase complex A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized. go-plus.json http://purl.obolibrary.org/obo/GO_0010368 GO:0009379 biolink:CellularComponent Holliday junction helicase complex A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA. go-plus.json http://purl.obolibrary.org/obo/GO_0009379 GO:0034335 biolink:MolecularActivity DNA negative supercoiling activity Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria. go-plus.json DNA-gyrase activity|DNA gyrase activity http://purl.obolibrary.org/obo/GO_0034335 CHEBI:62924 biolink:ChemicalSubstance 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62924 CHEBI:62921 biolink:ChemicalSubstance (S,S,S)-nicotianamine monoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62921 GO:0034336 biolink:MolecularActivity misfolded RNA binding Binding to an RNA molecule that has assumed an incorrect conformation. go-plus.json RNA chaperone http://purl.obolibrary.org/obo/GO_0034336 GO:0010365 biolink:BiologicalProcess positive regulation of ethylene biosynthetic process Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0010365 GO:0010366 biolink:BiologicalProcess negative regulation of ethylene biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0010366 GO:0034337 biolink:BiologicalProcess RNA folding The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure. go-plus.json RNA chaperone http://purl.obolibrary.org/obo/GO_0034337 CHEBI:62922 biolink:ChemicalSubstance 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62922 CHEBI:139036 biolink:ChemicalSubstance ent-Photinus luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139036 CHEBI:139032 biolink:ChemicalSubstance nerylneryl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139032 chebi_ph7_3 GO:0010360 biolink:BiologicalProcess negative regulation of anion channel activity Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_0010360 CHEBI:139033 biolink:ChemicalSubstance (-)-kolavenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139033 CHEBI:139034 biolink:ChemicalSubstance (+)-kolavenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139034 CHEBI:139035 biolink:ChemicalSubstance L-firefly luciferyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139035 CHEBI:139051 biolink:ChemicalSubstance phytoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_139051 chebi_ph7_3 CHEBI:139052 biolink:ChemicalSubstance inositol-1-phosphodihydroceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139052 chebi_ph7_3 CHEBI:139053 biolink:ChemicalSubstance inositol-1-phosphophytoceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139053 chebi_ph7_3 GO:0034327 biolink:MolecularActivity hexanoyltransferase activity Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0034327 GO:0034328 biolink:MolecularActivity decanoyltransferase activity Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0034328 GO:0034329 biolink:BiologicalProcess cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. go-plus.json http://purl.obolibrary.org/obo/GO_0034329 GO:0009390 biolink:CellularComponent dimethyl sulfoxide reductase complex An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide. go-plus.json dimethyl sulphoxide reductase complex http://purl.obolibrary.org/obo/GO_0009390 GO:0009391 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009391 GO:0009392 biolink:MolecularActivity N-acetyl-anhydromuramoyl-L-alanine amidase activity Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala. MetaCyc:RXN0-5225 go-plus.json http://purl.obolibrary.org/obo/GO_0009392 GO:0009393 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009393 GO:0009394 biolink:BiologicalProcess 2'-deoxyribonucleotide metabolic process The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json 2'-deoxyribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009394 GO:0009395 biolink:BiologicalProcess phospholipid catabolic process The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. go-plus.json phospholipid catabolism|phospholipid degradation|phospholipid breakdown http://purl.obolibrary.org/obo/GO_0009395 GO:0009385 biolink:MolecularActivity N-acylmannosamine-6-phosphate 2-epimerase activity Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate. EC:5.1.3.9|RHEA:25257|MetaCyc:NANE-RXN go-plus.json N-acylmannosamine-6-P epimerase activity http://purl.obolibrary.org/obo/GO_0009385 GO:0010374 biolink:BiologicalProcess stomatal complex development The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010374 GO:0009386 biolink:BiologicalProcess translational attenuation Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation. go-plus.json http://purl.obolibrary.org/obo/GO_0009386 GO:0010375 biolink:BiologicalProcess stomatal complex patterning The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010375 GO:0034320 biolink:MolecularActivity alcohol O-hexanoyltransferase activity Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0034320 GO:0010372 biolink:BiologicalProcess positive regulation of gibberellin biosynthetic process Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins. go-plus.json positive regulation of gibberellic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0010372 GO:0009387 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009387 GO:0034321 biolink:MolecularActivity alcohol O-octanoyltransferase activity Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0034321 GO:0009388 biolink:MolecularActivity obsolete antisense RNA OBSOLETE. (Was not defined before being made obsolete). go-plus.json antisense RNA http://purl.obolibrary.org/obo/GO_0009388 GO:0010373 biolink:BiologicalProcess negative regulation of gibberellin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins. go-plus.json negative regulation of gibberellic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0010373 GO:0034322 biolink:MolecularActivity alcohol O-decanoyltransferase activity Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0034322 GO:0009389 biolink:MolecularActivity dimethyl sulfoxide reductase activity Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O. EC:1.8.99.-|UM-BBD_reactionID:r0207 go-plus.json dimethyl sulphoxide reductase activity http://purl.obolibrary.org/obo/GO_0009389 GO:0010378 biolink:BiologicalProcess temperature compensation of the circadian clock The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms. go-plus.json regulation of the circadian clock by temperature http://purl.obolibrary.org/obo/GO_0010378 GO:0034323 biolink:MolecularActivity O-butanoyltransferase activity Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0034323 CHEBI:62934 biolink:ChemicalSubstance discadenine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62934 GO:0034324 biolink:MolecularActivity O-hexanoyltransferase activity Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0034324 GO:0010379 biolink:BiologicalProcess phaseic acid biosynthetic process The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA). MetaCyc:PWY-5271 go-plus.json http://purl.obolibrary.org/obo/GO_0010379 GO:0034325 biolink:MolecularActivity O-decanoyltransferase activity Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0034325 GO:0010376 biolink:BiologicalProcess stomatal complex formation The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010376 CHEBI:62932 biolink:ChemicalSubstance mycophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62932 chebi_ph7_3 GO:0010377 biolink:BiologicalProcess guard cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere. go-plus.json stomatal cell fate commitment http://purl.obolibrary.org/obo/GO_0010377 GO:0034326 biolink:MolecularActivity butanoyltransferase activity Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0034326 CHEBI:62933 biolink:ChemicalSubstance oxylipin anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62933 CHEBI:62938 biolink:ChemicalSubstance hepoxilin anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62938 CHEBI:139048 biolink:ChemicalSubstance dihydroceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_139048 chebi_ph7_3 CHEBI:62936 biolink:ChemicalSubstance homomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62936 CHEBI:62937 biolink:ChemicalSubstance icosanoid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62937 GO:0010370 biolink:CellularComponent perinucleolar chromocenter A chromocenter adjacent to the nucleolus. go-plus.json http://purl.obolibrary.org/obo/GO_0010370 GO:0010371 biolink:BiologicalProcess regulation of gibberellin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins. go-plus.json regulation of gibberellic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0010371 CHEBI:139020 biolink:ChemicalSubstance taurino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139020 GO:0034316 biolink:BiologicalProcess negative regulation of Arp2/3 complex-mediated actin nucleation Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0034316 GO:0010349 biolink:MolecularActivity L-galactose dehydrogenase activity Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+. MetaCyc:RXN-1884|RHEA:31559|EC:1.1.1.316 go-plus.json L-galactose 1-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0010349 GO:0034317 biolink:MolecularActivity nicotinic acid riboside kinase activity Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide. MetaCyc:RXN-8443 go-plus.json http://purl.obolibrary.org/obo/GO_0034317 GO:0034318 biolink:MolecularActivity alcohol O-acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule. go-plus.json alcohol acyltransferase activity|acyl-CoA:alcohol O-acyltransferase activity|acyl-coenzymeA:alcohol O-acyltransferase activity|acyl-CoA:ethanol O-acyltransferase|acyl-coenzymeA:ethanol O-acyltransferase activity|AEATase activity http://purl.obolibrary.org/obo/GO_0034318 GO:0010347 biolink:MolecularActivity L-galactose-1-phosphate phosphatase activity Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate. MetaCyc:RXNQT-4142|RHEA:26349 go-plus.json http://purl.obolibrary.org/obo/GO_0010347 GO:0034319 biolink:MolecularActivity alcohol O-butanoyltransferase activity Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0034319 GO:0010348 biolink:MolecularActivity lithium:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in). go-plus.json lithium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0010348 GO:0009360 biolink:CellularComponent DNA polymerase III complex The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. go-plus.json DNA polymerase III holoenzyme complex http://purl.obolibrary.org/obo/GO_0009360 GO:0009361 biolink:CellularComponent succinate-CoA ligase complex (ADP-forming) A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP. go-plus.json succinyl-CoA synthetase, ADP-forming http://purl.obolibrary.org/obo/GO_0009361 GO:0009362 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009362 GO:0009352 biolink:CellularComponent obsolete dihydrolipoyl dehydrogenase complex OBSOLETE. Complex that possesses dihydrolipoyl dehydrogenase activity. go-plus.json dihydrolipoyl dehydrogenase complex|dihydrolipoamide dehydrogenase complex http://purl.obolibrary.org/obo/GO_0009352 CHEBI:62941 biolink:ChemicalSubstance glycosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62941 GO:0010341 biolink:MolecularActivity gibberellin carboxyl-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0010341 GO:0010342 biolink:BiologicalProcess endosperm cellularization The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization. go-plus.json cellularization of endosperm http://purl.obolibrary.org/obo/GO_0010342 CHEBI:62942 biolink:ChemicalSubstance leukotriene anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62942 GO:0009353 biolink:CellularComponent mitochondrial oxoglutarate dehydrogenase complex A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus. go-plus.json http://purl.obolibrary.org/obo/GO_0009353 GO:0034310 biolink:BiologicalProcess primary alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. go-plus.json primary alcohol breakdown|monohydric alcohol catabolic process|primary alcohol catabolism|primary alcohol degradation http://purl.obolibrary.org/obo/GO_0034310 GO:0009354 biolink:CellularComponent obsolete dihydrolipoamide S-succinyltransferase complex OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex. go-plus.json dihydrolipoamide S-succinyltransferase complex http://purl.obolibrary.org/obo/GO_0009354 CHEBI:86910 biolink:ChemicalSubstance N-acetylhistidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_86910 GO:0034311 biolink:BiologicalProcess diol metabolic process The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. go-plus.json dihydric alcohol metabolic process|diol metabolism http://purl.obolibrary.org/obo/GO_0034311 GO:0010340 biolink:MolecularActivity carboxyl-O-methyltransferase activity Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0010340 GO:0009355 biolink:CellularComponent DNA polymerase V complex A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0009355 GO:0034312 biolink:BiologicalProcess diol biosynthetic process The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms. go-plus.json diol biosynthesis|dihydric alcohol biosynthetic process|diol anabolism|diol synthesis|diol formation http://purl.obolibrary.org/obo/GO_0034312 CHEBI:62945 biolink:ChemicalSubstance thromboxane anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62945 GO:0009356 biolink:CellularComponent aminodeoxychorismate synthase complex A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity. go-plus.json p-aminobenzoate synthetase complex|4-amino-4-deoxychorismate synthase complex|ADC synthase complex http://purl.obolibrary.org/obo/GO_0009356 GO:0010345 biolink:BiologicalProcess suberin biosynthetic process The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols. MetaCyc:PWY-1121 go-plus.json http://purl.obolibrary.org/obo/GO_0010345 GO:0034313 biolink:BiologicalProcess diol catabolic process The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms. go-plus.json diol catabolism|dihydric alcohol catabolic process|diol degradation|diol breakdown http://purl.obolibrary.org/obo/GO_0034313 GO:0009357 biolink:CellularComponent protein-N(PI)-phosphohistidine-sugar phosphotransferase complex An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system. go-plus.json http://purl.obolibrary.org/obo/GO_0009357 GO:0010346 biolink:BiologicalProcess shoot axis formation The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json shoot formation http://purl.obolibrary.org/obo/GO_0010346 CHEBI:139019 biolink:ChemicalSubstance AZD1979 oxetane hydrolysis product go-plus.json http://purl.obolibrary.org/obo/CHEBI_139019 chebi_ph7_3 GO:0009358 biolink:CellularComponent polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009358 GO:0034314 biolink:BiologicalProcess Arp2/3 complex-mediated actin nucleation The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins. go-plus.json branched actin filament nucleation|actin filament branch nucleation http://purl.obolibrary.org/obo/GO_0034314 GO:0010343 biolink:BiologicalProcess singlet oxygen-mediated programmed cell death Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes. go-plus.json light-dependent programmed cell death|programmed cell death in response to singlet oxygen http://purl.obolibrary.org/obo/GO_0010343 CHEBI:62943 biolink:ChemicalSubstance prostanoid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62943 GO:0009359 biolink:CellularComponent type II site-specific deoxyribonuclease complex A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell. go-plus.json type II restriction enzyme complex http://purl.obolibrary.org/obo/GO_0009359 GO:0034315 biolink:BiologicalProcess regulation of Arp2/3 complex-mediated actin nucleation Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0034315 CHEBI:62944 biolink:ChemicalSubstance sialic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_62944 GO:0010344 biolink:BiologicalProcess seed oilbody biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination. go-plus.json seed oil body organization|spherosome biogenesis|oleosome biogenesis http://purl.obolibrary.org/obo/GO_0010344 GO:0034305 biolink:BiologicalProcess regulation of asexual sporulation Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis. go-plus.json regulation of mitotic sporulation|regulation of asexual spore formation|regulation of mitotic spore formation http://purl.obolibrary.org/obo/GO_0034305 GO:0034306 biolink:BiologicalProcess regulation of sexual sporulation Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae. go-plus.json regulation of sexual spore formation|regulation of meiotic sporulation|MAPKKK cascade during sporulation|regulation of meiotic spore formation http://purl.obolibrary.org/obo/GO_0034306 GO:0010358 biolink:BiologicalProcess leaf shaping The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed. go-plus.json leaf structural organization http://purl.obolibrary.org/obo/GO_0010358 GO:0034307 biolink:BiologicalProcess regulation of ascospore formation Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae. go-plus.json MAPKKK cascade during sporulation http://purl.obolibrary.org/obo/GO_0034307 GO:0010359 biolink:BiologicalProcess regulation of anion channel activity Any process that modulates the frequency, rate or extent of anion channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_0010359 GO:0034308 biolink:BiologicalProcess primary alcohol metabolic process The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. go-plus.json primary alcohol metabolism|monohydric alcohol metabolic process http://purl.obolibrary.org/obo/GO_0034308 GO:0034309 biolink:BiologicalProcess primary alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. go-plus.json primary alcohol anabolism|monohydric alcohol biosynthetic process|primary alcohol synthesis|primary alcohol formation|primary alcohol biosynthesis http://purl.obolibrary.org/obo/GO_0034309 GO:0009370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009370 GO:0009371 biolink:BiologicalProcess positive regulation of transcription by pheromones Any process involving pheromones that activates or increases the rate of transcription. go-plus.json upregulation of transcription by pheromones|up regulation of transcription by pheromones|activation of transcription by pheromones|stimulation of transcription by pheromones|up-regulation of transcription by pheromones http://purl.obolibrary.org/obo/GO_0009371 GO:0009372 biolink:BiologicalProcess quorum sensing The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms. Wikipedia:Quorum_sensing go-plus.json cell-cell signaling involved in quorum sensing|detection of cell density by secreted molecule|quorum sensing system http://purl.obolibrary.org/obo/GO_0009372 goslim_pir|goslim_metagenomics GO:0009373 biolink:BiologicalProcess regulation of transcription by pheromones Any process involving pheromones that modulates the frequency, rate or extent of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0009373 GO:0010352 biolink:BiologicalProcess lithium ion export across the plasma membrane The directed movement of lithium ion out of a cell or organelle. go-plus.json lithium ion efflux|lithium export|lithium ion export http://purl.obolibrary.org/obo/GO_0010352 GO:0010353 biolink:BiologicalProcess response to trehalose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus. go-plus.json response to trehalose stimulus http://purl.obolibrary.org/obo/GO_0010353 GO:0009364 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009364 GO:0009365 biolink:CellularComponent protein histidine kinase complex A complex that possesses protein histidine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009365 GO:0010350 biolink:BiologicalProcess cellular response to magnesium starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium. go-plus.json http://purl.obolibrary.org/obo/GO_0010350 GO:0010351 biolink:BiologicalProcess lithium ion transport The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json lithium transport http://purl.obolibrary.org/obo/GO_0010351 GO:0009366 biolink:CellularComponent enterobactin synthetase complex A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway. MetaCyc:ENTMULTI-CPLX go-plus.json enterochelin synthetase complex http://purl.obolibrary.org/obo/GO_0009366 GO:0034300 biolink:BiologicalProcess sporangiospore formation The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0034300 GO:0034301 biolink:BiologicalProcess endospore formation The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0034301 GO:0009367 biolink:CellularComponent obsolete prepilin peptidase complex OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group. go-plus.json prepilin peptidase complex http://purl.obolibrary.org/obo/GO_0009367 GO:0010356 biolink:MolecularActivity homogentisate geranylgeranyltransferase activity Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol. go-plus.json http://purl.obolibrary.org/obo/GO_0010356 GO:0009368 biolink:CellularComponent endopeptidase Clp complex A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form. go-plus.json http://purl.obolibrary.org/obo/GO_0009368 goslim_pir GO:0010357 biolink:MolecularActivity homogentisate solanesyltransferase activity Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010357 GO:0034302 biolink:BiologicalProcess akinete formation The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0034302 GO:0009369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009369 GO:0010354 biolink:MolecularActivity homogentisate prenyltransferase activity Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0010354 GO:0034303 biolink:BiologicalProcess myxospore formation The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0034303 GO:0010355 biolink:MolecularActivity homogentisate farnesyltransferase activity Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol. go-plus.json http://purl.obolibrary.org/obo/GO_0010355 GO:0034304 biolink:BiologicalProcess actinomycete-type spore formation The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales. go-plus.json http://purl.obolibrary.org/obo/GO_0034304 CHEBI:139025 biolink:ChemicalSubstance 2-hydroxytetradecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139025 CHEBI:62958 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62958 CHEBI:62959 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62959 chebi_ph7_3 CHEBI:139021 biolink:ChemicalSubstance cis-alkene go-plus.json http://purl.obolibrary.org/obo/CHEBI_139021 chebi_ph7_3 CHEBI:139022 biolink:ChemicalSubstance 2-hydroxyheptadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139022 CHEBI:139023 biolink:ChemicalSubstance 2-hydroxyicosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139023 CHEBI:139024 biolink:ChemicalSubstance 2-hydroxydodecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139024 GO:0010327 biolink:MolecularActivity acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate. go-plus.json hexenol acetyltransferase http://purl.obolibrary.org/obo/GO_0010327 GO:0010328 biolink:MolecularActivity auxin influx transmembrane transporter activity Enables the transfer of auxin, from one side of a membrane to the other, into a cell. go-plus.json auxin influx facilitator http://purl.obolibrary.org/obo/GO_0010328 GO:0010325 biolink:BiologicalProcess raffinose family oligosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization). go-plus.json raffinose family oligosaccharide biosynthesis http://purl.obolibrary.org/obo/GO_0010325 GO:0010326 biolink:MolecularActivity methionine-oxo-acid transaminase activity Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid. MetaCyc:RXN-2201 go-plus.json http://purl.obolibrary.org/obo/GO_0010326 UBERON:0014701 biolink:AnatomicalEntity extraembryonic vascular system A vascular system that overlaps a umbilical cord and is part of a entire extraembryonic component. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014701 CHEBI:1729 biolink:ChemicalSubstance 4'-demethyldeoxypodophyllotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_1729 chebi_ph7_3 GO:0010329 biolink:MolecularActivity auxin efflux transmembrane transporter activity Enables the transfer of auxin, from one side of a membrane to the other, out of a cell. go-plus.json auxin efflux carrier|auxin efflux facilitator http://purl.obolibrary.org/obo/GO_0010329 GO:0009340 biolink:CellularComponent DNA topoisomerase IV complex A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0009340 GO:0009330 biolink:CellularComponent DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009330 GO:0009331 biolink:CellularComponent glycerol-3-phosphate dehydrogenase complex An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0009331 GO:0010320 biolink:MolecularActivity obsolete arginine/lysine endopeptidase activity OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles. go-plus.json arginine/lysine endopeptidase activity http://purl.obolibrary.org/obo/GO_0010320 GO:0009332 biolink:CellularComponent glutamate-tRNA ligase complex An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu). go-plus.json http://purl.obolibrary.org/obo/GO_0009332 GO:0009333 biolink:CellularComponent cysteine synthase complex Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A. go-plus.json http://purl.obolibrary.org/obo/GO_0009333 GO:0009334 biolink:CellularComponent 3-phenylpropionate dioxygenase complex Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol). MetaCyc:HCAMULTI-CPLX go-plus.json http://purl.obolibrary.org/obo/GO_0009334 GO:0010323 biolink:BiologicalProcess negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent). go-plus.json downregulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|inhibition of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down-regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway http://purl.obolibrary.org/obo/GO_0010323 GO:0010324 biolink:BiologicalProcess membrane invagination The infolding of a membrane. go-plus.json single-organism membrane invagination http://purl.obolibrary.org/obo/GO_0010324 goslim_yeast GO:0009335 biolink:CellularComponent obsolete holo-[acyl-carrier protein] synthase complex OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein]. go-plus.json holo-[acyl-carrier protein] synthase complex|holo-ACP synthase complex http://purl.obolibrary.org/obo/GO_0009335 GO:0010321 biolink:BiologicalProcess regulation of vegetative phase change Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development. go-plus.json http://purl.obolibrary.org/obo/GO_0010321 GO:0009336 biolink:CellularComponent sulfate adenylyltransferase complex (ATP) An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP. go-plus.json sulphate adenylyltransferase complex (ATP) http://purl.obolibrary.org/obo/GO_0009336 CHEBI:1722 biolink:ChemicalSubstance 3beta-hydroxy-Delta(5)-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1722 chebi_ph7_3 GO:0009337 biolink:CellularComponent sulfite reductase complex (NADPH) A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide. go-plus.json sulphite reductase complex (NADPH) http://purl.obolibrary.org/obo/GO_0009337 GO:0010322 biolink:BiologicalProcess regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent). go-plus.json regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway http://purl.obolibrary.org/obo/GO_0010322 GO:0009338 biolink:CellularComponent exodeoxyribonuclease V complex An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0009338 GO:0009339 biolink:CellularComponent glycolate oxidase complex An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN). go-plus.json http://purl.obolibrary.org/obo/GO_0009339 GO:0010338 biolink:BiologicalProcess leaf formation The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0010338 GO:0010339 biolink:CellularComponent external side of cell wall The side of the cell wall that is opposite to the side that faces the cell and its contents. go-plus.json http://purl.obolibrary.org/obo/GO_0010339 GO:0010336 biolink:BiologicalProcess gibberellic acid homeostasis Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation. go-plus.json gibberellin homeostasis http://purl.obolibrary.org/obo/GO_0010336 GO:0010337 biolink:BiologicalProcess regulation of salicylic acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid. go-plus.json regulation of salicylic acid metabolism http://purl.obolibrary.org/obo/GO_0010337 CHEBI:47395 biolink:ChemicalSubstance devancoaminyl vancomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_47395 GO:0009350 biolink:CellularComponent ethanolamine ammonia-lyase complex An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia. go-plus.json http://purl.obolibrary.org/obo/GO_0009350 GO:0009351 biolink:CellularComponent obsolete dihydrolipoamide S-acyltransferase complex OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide. go-plus.json dihydrolipoamide S-acyltransferase complex http://purl.obolibrary.org/obo/GO_0009351 GO:0010330 biolink:CellularComponent cellulose synthase complex A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall. go-plus.json CESA complex http://purl.obolibrary.org/obo/GO_0010330 GO:0009341 biolink:CellularComponent beta-galactosidase complex A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species. go-plus.json http://purl.obolibrary.org/obo/GO_0009341 goslim_metagenomics CHEBI:62974 biolink:ChemicalSubstance cellotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62974 chebi_ph7_3 GO:0009342 biolink:CellularComponent glutamate synthase complex (NADPH) A complex that possesses glutamate synthase (NADPH) activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009342 GO:0010331 biolink:MolecularActivity gibberellin binding Binding to a gibberellin, a plant hormone that regulates aspects of plant growth. go-plus.json gibberellic acid receptor|gibberellin receptor http://purl.obolibrary.org/obo/GO_0010331 GO:0009343 biolink:CellularComponent biotin carboxylase complex An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2). go-plus.json http://purl.obolibrary.org/obo/GO_0009343 GO:0009344 biolink:CellularComponent nitrite reductase complex [NAD(P)H] Complex that possesses nitrite reductase [NAD(P)H] activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009344 GO:0009345 biolink:CellularComponent glycine-tRNA ligase complex A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly). go-plus.json glycine-tRNA synthetase complex http://purl.obolibrary.org/obo/GO_0009345 GO:0010334 biolink:MolecularActivity sesquiterpene synthase activity Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons. go-plus.json http://purl.obolibrary.org/obo/GO_0010334 CHEBI:62978 biolink:ChemicalSubstance 4-hydroxyprolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62978 GO:0010335 biolink:BiologicalProcess response to non-ionic osmotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0010335 GO:0009346 biolink:CellularComponent ATP-independent citrate lyase complex Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity. This enzyme has only been found in bacteria. MetaCyc:ACECITLY-CPLX go-plus.json citrate synthase complex|citrate lyase complex http://purl.obolibrary.org/obo/GO_0009346 goslim_metagenomics CHEBI:62979 biolink:ChemicalSubstance 5-hydroxylysinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62979 GO:0010332 biolink:BiologicalProcess response to gamma radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. go-plus.json response to gamma ray|response to gamma-ray photon http://purl.obolibrary.org/obo/GO_0010332 CHEBI:62976 biolink:ChemicalSubstance cellopentaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62976 chebi_ph7_3 GO:0009347 biolink:CellularComponent aspartate carbamoyltransferase complex A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides. go-plus.json http://purl.obolibrary.org/obo/GO_0009347 GO:0010333 biolink:MolecularActivity terpene synthase activity Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units. go-plus.json http://purl.obolibrary.org/obo/GO_0010333 GO:0009348 biolink:CellularComponent ornithine carbamoyltransferase complex A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline. go-plus.json http://purl.obolibrary.org/obo/GO_0009348 GO:0009349 biolink:CellularComponent riboflavin synthase complex An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine. go-plus.json http://purl.obolibrary.org/obo/GO_0009349 goslim_metagenomics GO:0000982 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000982 GO:0000983 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000983 GO:0000984 biolink:MolecularActivity bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding Binding to a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase. go-plus.json eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding|bacterial-type RNA polymerase regulatory region DNA binding|eubacterial-type RNA polymerase regulatory region DNA binding http://purl.obolibrary.org/obo/GO_0000984 GO:0000985 biolink:MolecularActivity bacterial-type RNA polymerase core promoter sequence-specific DNA binding Binding to a DNA sequence that is part of the core promoter of a bacterial gene. go-plus.json eubacterial-type RNA polymerase core promoter sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0000985 GO:0000980 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000980 GO:0000981 biolink:MolecularActivity DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. go-plus.json transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, zinc ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription factor|RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated proximal promoter sequence-specific DNA binding|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding|RNA polymerase II transcription factor activity, copper ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding|transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding|RNA polymerase II transcription factor activity, sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0000981 GO:0010305 biolink:BiologicalProcess leaf vascular tissue pattern formation Vascular tissue pattern formation as it occurs in the leaf of vascular plants. go-plus.json http://purl.obolibrary.org/obo/GO_0010305 GO:0010306 biolink:BiologicalProcess rhamnogalacturonan II biosynthetic process The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms. go-plus.json http://purl.obolibrary.org/obo/GO_0010306 GO:0010303 biolink:MolecularActivity limit dextrinase activity Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan. MetaCyc:3.2.1.142-RXN|MetaCyc:3.2.1.10-RXN|MetaCyc:RXN-1824|EC:3.2.1.142 go-plus.json amylopectin-1,6-glucosidase activity|dextrin alpha-1,6-glucanohydrolase activity|R-enzyme http://purl.obolibrary.org/obo/GO_0010303 GO:0010304 biolink:BiologicalProcess PSII associated light-harvesting complex II catabolic process The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II. go-plus.json LHCII catabolism http://purl.obolibrary.org/obo/GO_0010304 GO:0010309 biolink:MolecularActivity acireductone dioxygenase [iron(II)-requiring] activity Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+). KEGG_REACTION:R07364|EC:1.13.11.54|Reactome:R-HSA-1237119|RHEA:24504|MetaCyc:R147-RXN go-plus.json 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase|acireductone dioxygenase activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)|ARD1|E-2'|1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity|acireductone dioxygenase (Fe2+-requiring) activity|ARD'|aci-reductone dioxygenase http://purl.obolibrary.org/obo/GO_0010309 CHEBI:62981 biolink:ChemicalSubstance 4-hydroxy-L-prolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62981 OBA:0100001 biolink:OntologyClass cellular component attribute The quality of a cellular_component. go-plus.json quality of cellular_component http://purl.obolibrary.org/obo/OBA_0100001 GO:0010307 biolink:MolecularActivity acetylglutamate kinase regulator activity Modulates the enzyme activity of acetylglutamate kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0010307 GO:0010308 biolink:MolecularActivity acireductone dioxygenase (Ni2+-requiring) activity Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate. KEGG_REACTION:R07363|RHEA:14161|EC:1.13.11.53|MetaCyc:R146-RXN go-plus.json 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity|acireductone dioxygenase activity|E-2 activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)|ARD activity http://purl.obolibrary.org/obo/GO_0010308 CHEBI:62980 biolink:ChemicalSubstance homoserinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62980 OBA:0100004 biolink:OntologyClass chemical entity attribute The quality of a chemical entity. go-plus.json quality of chemical entity http://purl.obolibrary.org/obo/OBA_0100004 OBA:0100005 biolink:OntologyClass protein attribute The quality of a protein. go-plus.json quality of protein http://purl.obolibrary.org/obo/OBA_0100005 OBA:0100002 biolink:OntologyClass biological process attribute The quality of a biological_process. go-plus.json quality of biological_process http://purl.obolibrary.org/obo/OBA_0100002 GO:0009310 biolink:BiologicalProcess amine catabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. go-plus.json amine catabolism|amine degradation|amine breakdown http://purl.obolibrary.org/obo/GO_0009310 OBA:0100003 biolink:OntologyClass anatomical entity attribute The quality of a anatomical entity. go-plus.json quality of anatomical entity http://purl.obolibrary.org/obo/OBA_0100003 GO:0009311 biolink:BiologicalProcess oligosaccharide metabolic process The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. go-plus.json oligosaccharide metabolism|multicellular organismal oligosaccharide metabolic process http://purl.obolibrary.org/obo/GO_0009311 goslim_yeast GO:0010301 biolink:MolecularActivity xanthoxin dehydrogenase activity Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH. MetaCyc:1.1.1.288-RXN|EC:1.1.1.288|RHEA:12548|KEGG_REACTION:R06954 go-plus.json ABA2|xanthoxin:NAD+ oxidoreductase activity|xanthoxin oxidase activity http://purl.obolibrary.org/obo/GO_0010301 GO:0009312 biolink:BiologicalProcess oligosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. go-plus.json oligosaccharide anabolism|oligosaccharide synthesis|oligosaccharide formation|oligosaccharide biosynthesis http://purl.obolibrary.org/obo/GO_0009312 CHEBI:62989 biolink:ChemicalSubstance chenodeoxycholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62989 chebi_ph7_3 GO:0010302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010302 GO:0009313 biolink:BiologicalProcess oligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. go-plus.json oligosaccharide catabolism|oligosaccharide degradation|oligosaccharide breakdown|multicellular organismal oligosaccharide catabolic process http://purl.obolibrary.org/obo/GO_0009313 GO:0009314 biolink:BiologicalProcess response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. go-plus.json response to radiation stimulus|response to electromagnetic radiation stimulus http://purl.obolibrary.org/obo/GO_0009314 GO:0010300 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010300 GO:0009315 biolink:BiologicalProcess obsolete drug resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json drug resistance http://purl.obolibrary.org/obo/GO_0009315 GO:0009316 biolink:CellularComponent 3-isopropylmalate dehydratase complex A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. MetaCyc:3-ISOPROPYLMALISOM-CPLX go-plus.json isopropylmalate isomerase complex http://purl.obolibrary.org/obo/GO_0009316 GO:0009317 biolink:CellularComponent acetyl-CoA carboxylase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex. go-plus.json ACCase complex http://purl.obolibrary.org/obo/GO_0009317 goslim_pir|goslim_metagenomics GO:0009318 biolink:CellularComponent exodeoxyribonuclease VII complex An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0009318 GO:0009319 biolink:CellularComponent cytochrome o ubiquinol oxidase complex A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups. MetaCyc:CYT-O-UBIOX-CPLX go-plus.json http://purl.obolibrary.org/obo/GO_0009319 GO:0000986 biolink:MolecularActivity bacterial-type cis-regulatory region sequence-specific DNA binding Binding to a specific upstream cis-regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the promoter of a bacterial gene (or cistron, or operon). go-plus.json bacterial-type RNA polymerase enhancer sequence-specific DNA binding|bacterial-type proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding|eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0000986 GO:0000987 biolink:MolecularActivity cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. The proximal promoter is in cis with and relatively close to the core promoter. go-plus.json core promoter proximal region DNA binding|core promoter proximal region sequence-specific DNA binding|promoter proximal region sequence-specific DNA binding|enhancer binding|cis-regulatory region binding|enhancer sequence-specific DNA binding|proximal promoter sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0000987 GO:0000988 biolink:MolecularActivity obsolete transcription factor activity, protein binding OBSOLETE. Binding to a protein or protein complex, to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json transcription factor activity|protein binding transcription factor activity http://purl.obolibrary.org/obo/GO_0000988 GO:0000989 biolink:MolecularActivity obsolete transcription factor activity, transcription factor binding OBSOLETE. Binding to a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json transcription factor binding transcription factor activity http://purl.obolibrary.org/obo/GO_0000989 GO:0000993 biolink:MolecularActivity RNA polymerase II complex binding Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits. go-plus.json RNAP II core binding|RNA polymerase II core binding http://purl.obolibrary.org/obo/GO_0000993 GO:0000994 biolink:MolecularActivity RNA polymerase III core binding Binding to an RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0000994 GO:0000995 biolink:MolecularActivity RNA polymerase III general transcription initiation factor activity A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III. go-plus.json RNA polymerase III transcription factor activity, sequence-specific DNA binding|transcription factor activity, core RNA polymerase III binding|RNA polymerase III general initiation factor activity|sequence-specific DNA binding RNA polymerase III transcription factor activity|core RNA polymerase III binding transcription factor activity http://purl.obolibrary.org/obo/GO_0000995 GO:0000996 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000996 GO:0000990 biolink:MolecularActivity obsolete transcription factor activity, core RNA polymerase binding OBSOLETE. Binding to an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json core RNA polymerase binding transcription factor activity http://purl.obolibrary.org/obo/GO_0000990 CHEBI:72316 biolink:ChemicalSubstance virulence factor go-plus.json http://purl.obolibrary.org/obo/CHEBI_72316 GO:0000991 biolink:MolecularActivity obsolete transcription factor activity, core RNA polymerase II binding OBSOLETE. Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. go-plus.json core RNA polymerase II binding transcription factor activity http://purl.obolibrary.org/obo/GO_0000991 GO:0000992 biolink:MolecularActivity RNA polymerase III cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes. go-plus.json http://purl.obolibrary.org/obo/GO_0000992 GO:0010316 biolink:CellularComponent pyrophosphate-dependent phosphofructokinase complex Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate. go-plus.json PFK complex http://purl.obolibrary.org/obo/GO_0010316 goslim_pir GO:0010317 biolink:CellularComponent pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity. go-plus.json PFK complex, alpha-subunit http://purl.obolibrary.org/obo/GO_0010317 GO:0010314 biolink:MolecularActivity phosphatidylinositol-5-phosphate binding Binding to phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position. go-plus.json http://purl.obolibrary.org/obo/GO_0010314 GO:0010315 biolink:BiologicalProcess auxin efflux The process involved in the transport of auxin out of the cell. go-plus.json auxin export http://purl.obolibrary.org/obo/GO_0010315 GO:0010318 biolink:CellularComponent pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity. go-plus.json PFK complex, beta-subunit http://purl.obolibrary.org/obo/GO_0010318 GO:0010319 biolink:CellularComponent stromule Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types. Wikipedia:Stromule go-plus.json Stroma-filled tubule http://purl.obolibrary.org/obo/GO_0010319 GO:0009320 biolink:CellularComponent phosphoribosylaminoimidazole carboxylase complex A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009320 GO:0009321 biolink:CellularComponent alkyl hydroperoxide reductase complex An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides. go-plus.json http://purl.obolibrary.org/obo/GO_0009321 GO:0009322 biolink:CellularComponent trimethylamine-N-oxide reductase complex An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_0009322 GO:0010312 biolink:BiologicalProcess detoxification of zinc ion Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion. go-plus.json http://purl.obolibrary.org/obo/GO_0010312 GO:0009323 biolink:CellularComponent ribosomal-protein-alanine N-acetyltransferase complex An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine. EC:2.3.1.128 go-plus.json http://purl.obolibrary.org/obo/GO_0009323 GO:0010313 biolink:MolecularActivity phytochrome binding Binding to a phytochrome. go-plus.json http://purl.obolibrary.org/obo/GO_0010313 GO:0009324 biolink:CellularComponent D-amino-acid dehydrogenase complex A protein complex that possesses D-amino-acid dehydrogenase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009324 GO:0010310 biolink:BiologicalProcess regulation of hydrogen peroxide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. go-plus.json regulation of hydrogen peroxide metabolism http://purl.obolibrary.org/obo/GO_0010310 GO:0009325 biolink:CellularComponent nitrate reductase complex An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0009325 GO:0010311 biolink:BiologicalProcess lateral root formation The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper. go-plus.json lateral root primordium development http://purl.obolibrary.org/obo/GO_0010311 GO:0009326 biolink:CellularComponent formate dehydrogenase complex An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2). EC:1.17.1.9 go-plus.json http://purl.obolibrary.org/obo/GO_0009326 GO:0009327 biolink:CellularComponent NAD(P)+ transhydrogenase complex (AB-specific) A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified. go-plus.json http://purl.obolibrary.org/obo/GO_0009327 GO:0009328 biolink:CellularComponent phenylalanine-tRNA ligase complex An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe). go-plus.json http://purl.obolibrary.org/obo/GO_0009328 GO:0009329 biolink:CellularComponent acetate CoA-transferase complex A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA. go-plus.json http://purl.obolibrary.org/obo/GO_0009329 GO:0000997 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000997 GO:0000998 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000998 GO:0000999 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000999 GO:1902779 biolink:BiologicalProcess cellular response to alkane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902779 GO:1902777 biolink:BiologicalProcess 6-sulfoquinovose(1-) catabolic process The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-). go-plus.json 6-sulfoquinovose(1-) degradation|6-sulfoquinovose(1-) breakdown|6-sulfoquinovose(1-) catabolism http://purl.obolibrary.org/obo/GO_1902777 GO:1902778 biolink:BiologicalProcess response to alkane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus. go-plus.json process resulting in tolerance to alkane http://purl.obolibrary.org/obo/GO_1902778 GO:1902775 biolink:BiologicalProcess mitochondrial large ribosomal subunit assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit. go-plus.json 39S ribosomal subunit, mitochondrial formation|39S ribosomal subunit, mitochondrial assembly|mitochondrial large ribosomal subunit formation http://purl.obolibrary.org/obo/GO_1902775 GO:1902776 biolink:BiologicalProcess 6-sulfoquinovose(1-) metabolic process The chemical reactions and pathways involving 6-sulfoquinovose(1-). go-plus.json 6-sulfoquinovose(1-) metabolism http://purl.obolibrary.org/obo/GO_1902776 GO:1902773 biolink:CellularComponent GTPase activator complex A protein complex which is capable of GTPase activator activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902773 GO:1902774 biolink:BiologicalProcess late endosome to lysosome transport The directed movement of substances from late endosome to lysosome. go-plus.json prevacuolar compartment to lysosome transport http://purl.obolibrary.org/obo/GO_1902774 GO:1902771 biolink:BiologicalProcess positive regulation of choline O-acetyltransferase activity Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity. go-plus.json positive regulation of choline acetyltransferase activity|up-regulation of choline acetylase activity|activation of choline acetylase activity|up regulation of choline acetyltransferase activity|up regulation of choline O-acetyltransferase activity|up regulation of acetyl-CoA:choline O-acetyltransferase activity|activation of acetyl-CoA:choline O-acetyltransferase activity|positive regulation of acetyl-CoA:choline O-acetyltransferase activity|positive regulation of CHOACTase activity|up regulation of CHOACTase activity|positive regulation of choline acetylase activity|upregulation of choline acetyltransferase activity|up regulation of choline acetylase activity|upregulation of choline O-acetyltransferase activity|up-regulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of choline acetyltransferase activity|upregulation of CHOACTase activity|activation of choline acetyltransferase activity|activation of choline O-acetyltransferase activity|upregulation of choline acetylase activity|up-regulation of choline O-acetyltransferase activity|upregulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of CHOACTase activity|activation of CHOACTase activity http://purl.obolibrary.org/obo/GO_1902771 GO:1902772 biolink:BiologicalProcess positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway. go-plus.json up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signalling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in H2O2 mediated signaling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|up regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in H2O2 mediated signaling pathway|activation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in H2O2 mediated signaling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signalling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signaling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signalling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|up-regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of phosphorelay signal transduction system involved in H2O2 mediated signaling pathway http://purl.obolibrary.org/obo/GO_1902772 GO:0034297 biolink:BiologicalProcess oidium formation The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus. go-plus.json http://purl.obolibrary.org/obo/GO_0034297 GO:1902780 biolink:BiologicalProcess response to nonane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902780 GO:1902781 biolink:BiologicalProcess cellular response to nonane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902781 GO:0034298 biolink:BiologicalProcess arthrospore formation The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation. go-plus.json arthroconidium formation http://purl.obolibrary.org/obo/GO_0034298 GO:0034299 biolink:BiologicalProcess reproductive blastospore formation The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota. go-plus.json blastoconidium formation http://purl.obolibrary.org/obo/GO_0034299 GO:0034290 biolink:MolecularActivity holin activity A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0034290 GO:0034291 biolink:MolecularActivity canonical holin activity A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0034291 GO:0034292 biolink:MolecularActivity pinholin activity A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0034292 GO:0034293 biolink:BiologicalProcess sexual sporulation The formation of spores derived from the products of meiosis. go-plus.json meiotic spore formation|sexual spore formation|meiotic sporulation http://purl.obolibrary.org/obo/GO_0034293 goslim_aspergillus GO:0034294 biolink:BiologicalProcess sexual spore wall assembly The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis. go-plus.json sexual spore wall formation http://purl.obolibrary.org/obo/GO_0034294 GO:0034295 biolink:BiologicalProcess basidiospore formation The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium. go-plus.json http://purl.obolibrary.org/obo/GO_0034295 GO:0034296 biolink:BiologicalProcess zygospore formation The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away. go-plus.json http://purl.obolibrary.org/obo/GO_0034296 GO:1902788 biolink:BiologicalProcess response to isooctane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902788 GO:1902789 biolink:BiologicalProcess cellular response to isooctane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902789 GO:1902786 biolink:BiologicalProcess response to dodecane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902786 GO:1902787 biolink:BiologicalProcess cellular response to dodecane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902787 GO:1902784 biolink:BiologicalProcess response to undecane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902784 GO:1902785 biolink:BiologicalProcess cellular response to undecane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902785 GO:1902782 biolink:BiologicalProcess response to decane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902782 GO:1902783 biolink:BiologicalProcess cellular response to decane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902783 GO:0034286 biolink:BiologicalProcess response to maltose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus. go-plus.json response to maltose stimulus http://purl.obolibrary.org/obo/GO_0034286 GO:1902791 biolink:BiologicalProcess undecan-2-one biosynthetic process The chemical reactions and pathways resulting in the formation of undecan-2-one. go-plus.json undecan-2-one biosynthesis|undecan-2-one anabolism|undecan-2-one synthesis|undecan-2-one formation http://purl.obolibrary.org/obo/GO_1902791 GO:1902792 biolink:CellularComponent pyrroline-5-carboxylate reductase complex A protein complex which is capable of pyrroline-5-carboxylate reductase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902792 GO:0034287 biolink:BiologicalProcess detection of monosaccharide stimulus The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal. go-plus.json perception of monosaccharide stimulus http://purl.obolibrary.org/obo/GO_0034287 GO:0034288 biolink:BiologicalProcess detection of disaccharide stimulus The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal. go-plus.json perception of disaccharide stimulus http://purl.obolibrary.org/obo/GO_0034288 GO:1902790 biolink:BiologicalProcess undecan-2-one metabolic process The chemical reactions and pathways involving undecan-2-one. go-plus.json undecan-2-one metabolism http://purl.obolibrary.org/obo/GO_1902790 GO:0034289 biolink:BiologicalProcess detection of maltose stimulus The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of maltose stimulus http://purl.obolibrary.org/obo/GO_0034289 CHEBI:1774 biolink:ChemicalSubstance (E)-4-(trimethylammonio)but-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1774 GO:0034280 biolink:MolecularActivity ent-sandaracopimaradiene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate. MetaCyc:RXN-4884|EC:4.2.3.29|RHEA:25536|KEGG_REACTION:R09120 go-plus.json ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity http://purl.obolibrary.org/obo/GO_0034280 GO:0034281 biolink:MolecularActivity ent-isokaurene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0034281 GO:0034282 biolink:MolecularActivity ent-pimara-8(14),15-diene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate. MetaCyc:RXN-7788|EC:4.2.3.30|RHEA:25540|KEGG_REACTION:R09121 go-plus.json ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity http://purl.obolibrary.org/obo/GO_0034282 GO:0034283 biolink:MolecularActivity syn-stemod-13(17)-ene synthase activity Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate. EC:4.2.3.34|RHEA:25556|MetaCyc:RXN-9291|KEGG_REACTION:R09116 go-plus.json stemodene synthase activity|stemod-13(17)-ene synthase activity|syn-stemodene synthase activity|9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming] activity|exo-stemodene synthase activity http://purl.obolibrary.org/obo/GO_0034283 GO:0034284 biolink:BiologicalProcess response to monosaccharide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. go-plus.json response to monosaccharide stimulus http://purl.obolibrary.org/obo/GO_0034284 GO:0034285 biolink:BiologicalProcess response to disaccharide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus. go-plus.json response to disaccharide stimulus http://purl.obolibrary.org/obo/GO_0034285 GO:1902799 biolink:BiologicalProcess regulation of phosphodiesterase I activity Any process that modulates the frequency, rate or extent of phosphodiesterase I activity. go-plus.json regulation of PDE I activity|regulation of 5'NPDE activity|regulation of alkaline phosphodiesterase activity|regulation of 5'-PDE activity|regulation of exonuclease I activity|regulation of 5'-exonuclease activity|regulation of orthophosphoric diester phosphohydrolase activity|regulation of phosphodiesterase activity|regulation of 5'-PDase activity|regulation of 5'-phosphodiesterase activity|regulation of 5'-nucleotide phosphodiesterase activity|regulation of 5'-NPDase activity|regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|regulation of oligonucleate 5'-nucleotidohydrolase activity http://purl.obolibrary.org/obo/GO_1902799 GO:1902797 biolink:BiologicalProcess negative regulation of snoRNA processing Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing. go-plus.json down-regulation of snoRNA processing|inhibition of snoRNA processing|down regulation of snoRNA processing|downregulation of snoRNA processing http://purl.obolibrary.org/obo/GO_1902797 GO:1902798 biolink:BiologicalProcess positive regulation of snoRNA processing Any process that activates or increases the frequency, rate or extent of snoRNA processing. go-plus.json up-regulation of snoRNA processing|upregulation of snoRNA processing|up regulation of snoRNA processing|activation of snoRNA processing http://purl.obolibrary.org/obo/GO_1902798 GO:1902795 biolink:BiologicalProcess heterochromatin domain assembly The aggregation, arrangement and bonding together of a set of components to form a heterochromatin domain. go-plus.json heterochromatin domain formation|HOOD formation|HOOD assembly http://purl.obolibrary.org/obo/GO_1902795 GO:1902796 biolink:BiologicalProcess regulation of snoRNA processing Any process that modulates the frequency, rate or extent of snoRNA processing. go-plus.json http://purl.obolibrary.org/obo/GO_1902796 GO:1902793 biolink:CellularComponent glutamate decarboxylase complex A protein complex which is capable of glutamate decarboxylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902793 GO:1902794 biolink:BiologicalProcess heterochromatin island assembly The aggregation, arrangement and bonding together of a set of components to form a heterochromatin island. go-plus.json heterochromatin island formation http://purl.obolibrary.org/obo/GO_1902794 GO:0034275 biolink:BiologicalProcess kynurenic acid metabolic process The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. go-plus.json kynurenic acid metabolism|4-hydroxyquinoline-2-carboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0034275 GO:0034276 biolink:BiologicalProcess kynurenic acid biosynthetic process The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. go-plus.json kynurenic acid synthesis|kynurenic acid biosynthesis|kynurenic acid formation|4-hydroxyquinoline-2-carboxylic acid biosynthetic process|kynurenic acid anabolism http://purl.obolibrary.org/obo/GO_0034276 GO:0034277 biolink:MolecularActivity ent-cassa-12,15-diene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate. KEGG_REACTION:R09119|RHEA:25532|MetaCyc:RXN-4881|EC:4.2.3.28 go-plus.json ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming) activity http://purl.obolibrary.org/obo/GO_0034277 GO:0034278 biolink:MolecularActivity stemar-13-ene synthase activity Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate. EC:4.2.3.33|RHEA:25552|KEGG_REACTION:R09115|MetaCyc:RXN-4882 go-plus.json 9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming) activity http://purl.obolibrary.org/obo/GO_0034278 GO:0034279 biolink:MolecularActivity syn-pimara-7,15-diene synthase activity Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate. EC:4.2.3.35|KEGG_REACTION:R09117|RHEA:25560|MetaCyc:RXN-4883 go-plus.json 9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming) activity http://purl.obolibrary.org/obo/GO_0034279 GO:0034270 biolink:CellularComponent Cvt complex A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p. go-plus.json cytoplasm to vacuole targeting complex|cytoplasm-to-vacuole targeting complex http://purl.obolibrary.org/obo/GO_0034270 GO:0034271 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class III, type I A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p. go-plus.json phosphatidylinositol 3-kinase complex I|autophagy-specific phosphatidylinositol 3-kinase (PtdIns3K) complex|PtdIns-3-kinase complex I http://purl.obolibrary.org/obo/GO_0034271 CHEBI:139098 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-beta-D-galactosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139098 chebi_ph7_3 GO:0034272 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class III, type II A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p. go-plus.json PtdIns-3-kinase complex II|phosphatidylinositol 3-kinase complex II http://purl.obolibrary.org/obo/GO_0034272 GO:0034273 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034273 GO:0034274 biolink:CellularComponent Atg12-Atg5-Atg16 complex A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p. go-plus.json http://purl.obolibrary.org/obo/GO_0034274 CHEBI:140083 biolink:ChemicalSubstance O(3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140083 chebi_ph7_3 CHEBI:140084 biolink:ChemicalSubstance all-trans-retinyl octanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140084 chebi_ph7_3 CHEBI:140082 biolink:ChemicalSubstance 2-octanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140082 chebi_ph7_3 CHEBI:140080 biolink:ChemicalSubstance O(3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140080 chebi_ph7_3 CHEBI:140089 biolink:ChemicalSubstance all-trans-retinyl dodecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140089 chebi_ph7_3 CHEBI:140087 biolink:ChemicalSubstance O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140087 chebi_ph7_3 CHEBI:140088 biolink:ChemicalSubstance 2-dodecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140088 chebi_ph7_3 CHEBI:140085 biolink:ChemicalSubstance O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140085 chebi_ph7_3 CHEBI:140086 biolink:ChemicalSubstance 6,7-dichloro-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_140086 GO:0034264 biolink:BiologicalProcess isopentenyl adenine metabolic process The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine. go-plus.json isopentenyladenine metabolic process|isopentenyl adenine metabolism http://purl.obolibrary.org/obo/GO_0034264 GO:0034265 biolink:BiologicalProcess isopentenyl adenine biosynthetic process The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine. go-plus.json isopentenyl adenine formation|isopentenyl adenine biosynthesis|isopentenyladenine biosynthetic process|isopentenyl adenine anabolism|isopentenyl adenine synthesis http://purl.obolibrary.org/obo/GO_0034265 GO:0034266 biolink:BiologicalProcess isopentenyl adenine catabolic process The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine. go-plus.json isopentenyl adenine catabolism|isopentenyl adenine degradation|isopentenyladenine catabolic process|isopentenyl adenine breakdown http://purl.obolibrary.org/obo/GO_0034266 GO:0034267 biolink:BiologicalProcess discadenine metabolic process The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid. go-plus.json discadenine metabolism http://purl.obolibrary.org/obo/GO_0034267 GO:0034268 biolink:BiologicalProcess discadenine biosynthetic process The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid. go-plus.json discadenine anabolism|discadenine synthesis|discadenine formation|discadenine biosynthesis http://purl.obolibrary.org/obo/GO_0034268 GO:0034269 biolink:BiologicalProcess discadenine catabolic process The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid. go-plus.json discadenine degradation|discadenine breakdown|discadenine catabolism http://purl.obolibrary.org/obo/GO_0034269 GO:0034260 biolink:BiologicalProcess negative regulation of GTPase activity Any process that stops or reduces the rate of GTP hydrolysis by a GTPase. go-plus.json down-regulation of Rho GTPase activity|negative regulation of Rho GTPase activity|downregulation of Rab GTPase activity|inhibition of Ras GTPase activity|inhibition of GTPase activity|negative regulation of Rab GTPase activity|inhibition of regulation of Ran GTPase activity|down regulation of Ras GTPase activity|down-regulation of Rab GTPase activity|inhibition of Rho GTPase activity|downregulation of Ras GTPase activity|down regulation of regulation of Ran GTPase activity|down regulation of GTPase activity|downregulation of regulation of Ran GTPase activity|down regulation of Rho GTPase activity|negative regulation of guanosinetriphosphatase activity|down-regulation of Ras GTPase activity|inhibition of Rab GTPase activity|downregulation of GTPase activity|negative regulation of Ras GTPase activity|downregulation of Rho GTPase activity|negative regulation of Ran GTPase activity|down-regulation of regulation of Ran GTPase activity|down regulation of Rab GTPase activity|down-regulation of GTPase activity http://purl.obolibrary.org/obo/GO_0034260 GO:0034261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034261 GO:0034262 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034262 GO:0034263 biolink:BiologicalProcess positive regulation of autophagy in response to ER overload The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy. go-plus.json autophagy in response to ER stress|autophagy in response to endoplasmic reticulum overload http://purl.obolibrary.org/obo/GO_0034263 CHEBI:139083 biolink:ChemicalSubstance (E)-hex-4-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139083 CHEBI:139085 biolink:ChemicalSubstance (9R,13R)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139085 CHEBI:140077 biolink:ChemicalSubstance 6-chloro-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_140077 GO:0009297 biolink:BiologicalProcess pilus assembly The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles. go-plus.json fimbria biogenesis|fimbriae biogenesis|fimbrium assembly|fimbria assembly|fimbriae assembly|fimbrium biogenesis|fimbrial assembly|pilus formation|pilus biogenesis http://purl.obolibrary.org/obo/GO_0009297 GO:0034253 biolink:BiologicalProcess positive regulation of cellular amide catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. go-plus.json positive regulation of amide catabolism|positive regulation of amide breakdown|positive regulation of amide degradation http://purl.obolibrary.org/obo/GO_0034253 GO:0010286 biolink:BiologicalProcess heat acclimation Any process that increases heat tolerance of an organism in response to high temperatures. go-plus.json thermotolerance http://purl.obolibrary.org/obo/GO_0010286 GO:0009298 biolink:BiologicalProcess GDP-mannose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-mannose synthesis|GDP-mannose formation|GDP-mannose biosynthesis|GDP-mannose anabolism http://purl.obolibrary.org/obo/GO_0009298 GO:0010287 biolink:CellularComponent plastoglobule A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids. go-plus.json PG|plastoglobuli http://purl.obolibrary.org/obo/GO_0010287 GO:0034254 biolink:BiologicalProcess regulation of urea catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea. go-plus.json regulation of urea degradation|regulation of urea breakdown|regulation of urea catabolism http://purl.obolibrary.org/obo/GO_0034254 GO:0009299 biolink:BiologicalProcess mRNA transcription The cellular synthesis of messenger RNA (mRNA) from a DNA template. go-plus.json mRNA biosynthetic process|mRNA biosynthesis|mRNA synthesis|cellular mRNA transcription http://purl.obolibrary.org/obo/GO_0009299 GO:0010284 biolink:MolecularActivity lariciresinol reductase activity Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+. MetaCyc:RXN-8679|MetaCyc:RXN-8684 go-plus.json http://purl.obolibrary.org/obo/GO_0010284 GO:0034255 biolink:BiologicalProcess regulation of urea metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea. go-plus.json regulation of urea metabolism http://purl.obolibrary.org/obo/GO_0034255 GO:0034256 biolink:MolecularActivity chlorophyll(ide) b reductase activity Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+. EC:1.1.1.294|MetaCyc:RXN-7678 go-plus.json chlorophyll b reductase activity|Chl b reductase activity|chlorophyllide b reductase activity http://purl.obolibrary.org/obo/GO_0034256 GO:0010285 biolink:MolecularActivity L,L-diaminopimelate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+). MetaCyc:RXN-7737|RHEA:23988|KEGG_REACTION:R07613|EC:2.6.1.83 go-plus.json LL-diaminopimelate transaminase activity|LL-DAP-AT activity|LL-DAP aminotransferase activity|LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|LL-diaminopimelate aminotransferase activity http://purl.obolibrary.org/obo/GO_0010285 GO:0034257 biolink:MolecularActivity nicotinamide riboside transmembrane transporter activity Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other. RHEA:33163 go-plus.json http://purl.obolibrary.org/obo/GO_0034257 GO:0034258 biolink:BiologicalProcess nicotinamide riboside transport The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0034258 GO:0034259 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034259 GO:0010288 biolink:BiologicalProcess response to lead ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010288 GO:0010289 biolink:BiologicalProcess homogalacturonan biosynthetic process The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. MetaCyc:PWY-1061 go-plus.json http://purl.obolibrary.org/obo/GO_0010289 GO:0010282 biolink:CellularComponent senescence-associated vacuole A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast. go-plus.json senescence associated vacuole http://purl.obolibrary.org/obo/GO_0010282 GO:0034250 biolink:BiologicalProcess positive regulation of cellular amide metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. go-plus.json positive regulation of amide metabolism http://purl.obolibrary.org/obo/GO_0034250 GO:0010283 biolink:MolecularActivity pinoresinol reductase activity Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+. MetaCyc:RXN-8678|MetaCyc:RXN-8683 go-plus.json http://purl.obolibrary.org/obo/GO_0010283 GO:0034251 biolink:BiologicalProcess regulation of cellular amide catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. go-plus.json regulation of amide degradation|regulation of amide breakdown|regulation of amide catabolism http://purl.obolibrary.org/obo/GO_0034251 GO:0010280 biolink:MolecularActivity UDP-L-rhamnose synthase activity Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O. MetaCyc:RXN-5482 go-plus.json UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity http://purl.obolibrary.org/obo/GO_0010280 GO:0034252 biolink:BiologicalProcess negative regulation of cellular amide catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. go-plus.json negative regulation of amide catabolism|negative regulation of amide degradation|negative regulation of amide breakdown http://purl.obolibrary.org/obo/GO_0034252 GO:0010281 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010281 CHEBI:139094 biolink:ChemicalSubstance 2'-deoxyribose 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139094 CHEBI:139095 biolink:ChemicalSubstance 2'-deoxyribose 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139095 chebi_ph7_3 CHEBI:139090 biolink:ChemicalSubstance inositol phosphomannosylinositol-1-phospho-N-acylphytosphingosine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139090 chebi_ph7_3 GO:0010297 biolink:MolecularActivity heteropolysaccharide binding Binding to a heteropolysaccharide, a glycan composed of more than one type of monosaccharide residue. go-plus.json heteroglycan binding http://purl.obolibrary.org/obo/GO_0010297 GO:0034242 biolink:BiologicalProcess negative regulation of syncytium formation by plasma membrane fusion Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0034242 GO:0010298 biolink:MolecularActivity dihydrocamalexic acid decarboxylase activity Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+. MetaCyc:RXN-8275|RHEA:34807 go-plus.json http://purl.obolibrary.org/obo/GO_0010298 GO:0034243 biolink:BiologicalProcess regulation of transcription elongation from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. go-plus.json regulation of gene-specific transcription elongation from RNA polymerase II promoter|regulation of RNA elongation from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0034243 GO:0034244 biolink:BiologicalProcess negative regulation of transcription elongation from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. go-plus.json negative regulation of gene-specific transcription elongation from RNA polymerase II promoter|negative regulation of RNA elongation from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0034244 GO:0010295 biolink:MolecularActivity (+)-abscisic acid 8'-hydroxylase activity Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+). RHEA:12897|KEGG_REACTION:R07202|MetaCyc:1.14.13.93-RXN|EC:1.14.14.137 go-plus.json abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)|ABA 8'-hydroxylase activity|(+)-ABA 8'-hydroxylase activity|ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity|abscisic acid 8'-hydroxylase activity http://purl.obolibrary.org/obo/GO_0010295 GO:0034245 biolink:CellularComponent mitochondrial DNA-directed RNA polymerase complex A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form. go-plus.json mitochondrial RNA polymerase holoenzyme complex|mitochondrial RNA polymerase complex http://purl.obolibrary.org/obo/GO_0034245 GO:0010296 biolink:MolecularActivity prenylcysteine methylesterase activity Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+. RHEA:48520|MetaCyc:RXN-8409 go-plus.json http://purl.obolibrary.org/obo/GO_0010296 GO:0034246 biolink:MolecularActivity mitochondrial transcription factor activity Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase. go-plus.json transcription factor activity, mitochondrial proximal promoter sequence-specific binding|mitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding|mitochondrial transcription initiation factor activity|mitochondrial RNA polymerase binding promoter specificity activity|mitochondrial transcription factor activity|mitochondrial sequence-specific DNA binding transcription factor activity|mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity|mitochondrial RNA polymerase promoter specificity activity|mitochondrial DNA-binding transcription factor activity|mitochondrial sequence-specific DNA-binding transcription factor activity|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding mitochondrial RNA polymerase transcription factor activity|mitochondrial polymerase transcription factor activity|transcription factor activity, mitochondrial RNA polymerase core promoter proximal region sequence-specific binding|transcription factor activity, mitochondrial RNA polymerase core promoter sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0034246 GO:0034247 biolink:BiologicalProcess snoRNA splicing The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0034247 GO:0034248 biolink:BiologicalProcess regulation of cellular amide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. go-plus.json regulation of amide metabolism http://purl.obolibrary.org/obo/GO_0034248 GO:0010299 biolink:BiologicalProcess detoxification of cobalt ion Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion. go-plus.json http://purl.obolibrary.org/obo/GO_0010299 GO:0034249 biolink:BiologicalProcess negative regulation of cellular amide metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. go-plus.json negative regulation of amide metabolism http://purl.obolibrary.org/obo/GO_0034249 GO:0010290 biolink:MolecularActivity chlorophyll catabolite transmembrane transporter activity Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0010290 GO:0010293 biolink:MolecularActivity abscisic aldehyde oxidase activity Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+). KEGG_REACTION:R06957|MetaCyc:1.2.3.14-RXN|RHEA:20529|EC:1.2.3.14 go-plus.json AOdelta|abscisic-aldehyde oxidase activity|AAO3|abscisic-aldehyde:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0010293 GO:0010294 biolink:MolecularActivity abscisic acid glucosyltransferase activity Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP. MetaCyc:RXN-8155|RHEA:31031 go-plus.json http://purl.obolibrary.org/obo/GO_0010294 GO:0010291 biolink:MolecularActivity carotene beta-ring hydroxylase activity Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene. go-plus.json beta-carotene hydroxylase activity http://purl.obolibrary.org/obo/GO_0010291 GO:0034240 biolink:BiologicalProcess negative regulation of macrophage fusion Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0034240 CHEBI:139089 biolink:ChemicalSubstance N(6)-methyl-2'-deoxyadenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139089 GO:0034241 biolink:BiologicalProcess positive regulation of macrophage fusion Any process that activates or increases the frequency, rate or extent of macrophage fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0034241 GO:0010292 biolink:MolecularActivity GTP:GDP antiporter activity Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out). go-plus.json http://purl.obolibrary.org/obo/GO_0010292 CHEBI:139064 biolink:ChemicalSubstance (15Z)-12-oxophyto-10,15-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139064 GO:0034239 biolink:BiologicalProcess regulation of macrophage fusion Any process that modulates the frequency, rate or extent of macrophage fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0034239 GO:0009280 biolink:CellularComponent obsolete cell wall inner membrane OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus. go-plus.json cell wall inner membrane|cytoplasmic membrane http://purl.obolibrary.org/obo/GO_0009280 GO:0009281 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009281 GO:0009282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009282 GO:0009283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009283 GO:0009284 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009284 GO:0009285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009285 GO:0009275 biolink:CellularComponent Gram-positive-bacterium-type cell wall A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria. go-plus.json 20-80nm peptidoglycan-based cell wall|cell wall of Gram-positive Bacteria http://purl.obolibrary.org/obo/GO_0009275 GO:0010264 biolink:BiologicalProcess myo-inositol hexakisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds. go-plus.json myo-inositol hexakisphosphate formation|myo-inositol hexakisphosphate biosynthesis|phytate biosynthetic process|phytate biosynthesis|myo-inositol hexakisphosphate anabolism|myo-inositol hexakisphosphate synthesis http://purl.obolibrary.org/obo/GO_0010264 GO:0034231 biolink:BiologicalProcess islet amyloid polypeptide processing The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP). go-plus.json islet amyloid polypeptide formation|IAPP formation|islet amyloid peptide processing|islet amyloid peptide formation|IAPP processing http://purl.obolibrary.org/obo/GO_0034231 GO:0009276 biolink:CellularComponent Gram-negative-bacterium-type cell wall The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain. go-plus.json 1-2nm peptidoglycan-based cell wall|cell wall inner membrane http://purl.obolibrary.org/obo/GO_0009276 goslim_metagenomics GO:0034232 biolink:BiologicalProcess ascospore wall chitin catabolic process The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores. go-plus.json ascospore wall chitin breakdown|ascospore wall chitin catabolism|ascospore wall chitin degradation http://purl.obolibrary.org/obo/GO_0034232 GO:0010265 biolink:BiologicalProcess SCF complex assembly The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex. go-plus.json http://purl.obolibrary.org/obo/GO_0010265 GO:0009277 biolink:CellularComponent fungal-type cell wall A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure. go-plus.json chitin-containing cell wall|beta-glucan-containing cell wall|chitin- and beta-glucan-containing cell wall http://purl.obolibrary.org/obo/GO_0009277 GO:0010262 biolink:BiologicalProcess somatic embryogenesis Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes. go-plus.json http://purl.obolibrary.org/obo/GO_0010262 CHEBI:1784 biolink:ChemicalSubstance biphenyl-4-amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_1784 chebi_ph7_3 GO:0034233 biolink:BiologicalProcess regulation of cell wall chitin catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin. go-plus.json regulation of cell wall chitin catabolism|regulation of cell wall chitin degradation|regulation of cell wall chitin breakdown http://purl.obolibrary.org/obo/GO_0034233 GO:0010263 biolink:BiologicalProcess tricyclic triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings. go-plus.json tricyclic triterpenoid anabolism|tricyclic triterpenoid synthesis|tricyclic triterpenoid formation|tricyclic triterpenoid biosynthesis http://purl.obolibrary.org/obo/GO_0010263 GO:0009278 biolink:CellularComponent obsolete murein sacculus OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria. go-plus.json murein sacculus http://purl.obolibrary.org/obo/GO_0009278 GO:0034234 biolink:BiologicalProcess regulation of ascospore wall chitin catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin. go-plus.json regulation of ascospore wall chitin catabolism|regulation of ascospore wall chitin degradation|regulation of ascospore wall chitin breakdown http://purl.obolibrary.org/obo/GO_0034234 GO:0034235 biolink:MolecularActivity GPI anchor binding Binding to a glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes. go-plus.json glycosylphosphatidylinositol binding http://purl.obolibrary.org/obo/GO_0034235 GO:0009279 biolink:CellularComponent cell outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. go-plus.json outer membrane of cell http://purl.obolibrary.org/obo/GO_0009279 GO:0010268 biolink:BiologicalProcess brassinosteroid homeostasis Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010268 GO:0010269 biolink:BiologicalProcess response to selenium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion. go-plus.json http://purl.obolibrary.org/obo/GO_0010269 GO:0034236 biolink:MolecularActivity protein kinase A catalytic subunit binding Binding to one or both of the catalytic subunits of protein kinase A. go-plus.json PKA catalytic subunit binding http://purl.obolibrary.org/obo/GO_0034236 GO:0010266 biolink:BiologicalProcess response to vitamin B1 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus. go-plus.json response to thiamine|response to thiamin http://purl.obolibrary.org/obo/GO_0010266 GO:0034237 biolink:MolecularActivity protein kinase A regulatory subunit binding Binding to one or both of the regulatory subunits of protein kinase A. go-plus.json protein kinase A anchoring activity|PKA regulatory subunit binding http://purl.obolibrary.org/obo/GO_0034237 GO:0034238 biolink:BiologicalProcess macrophage fusion The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0034238 GO:0010267 biolink:BiologicalProcess production of ta-siRNAs involved in RNA interference Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs. go-plus.json RNA interference, production of ta-siRNAs http://purl.obolibrary.org/obo/GO_0010267 GO:0010260 biolink:BiologicalProcess animal organ senescence The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0010260 GO:0010261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010261 CHEBI:139057 biolink:ChemicalSubstance pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_139057 GO:0034230 biolink:BiologicalProcess enkephalin processing The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide. go-plus.json peptide enkephalin formation|enkephalin formation|peptide enkephalin processing http://purl.obolibrary.org/obo/GO_0034230 CHEBI:139072 biolink:ChemicalSubstance psilocybin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139072 chebi_ph7_3 CHEBI:139073 biolink:ChemicalSubstance N(5)-phospho-L-glutamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139073 chebi_ph7_3 CHEBI:139070 biolink:ChemicalSubstance norbaeocystin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139070 chebi_ph7_3 CHEBI:139071 biolink:ChemicalSubstance baeocystin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139071 chebi_ph7_3 GO:0034228 biolink:MolecularActivity ethanolamine transmembrane transporter activity Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine. RHEA:32747 go-plus.json monoethanolamine transmembrane transporter activity|ethanolamine permease activity|2-aminoethanol transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034228 GO:0009290 biolink:BiologicalProcess DNA import into cell involved in transformation The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell. go-plus.json DNA import into cell|DNA transport into cell during transformation|DNA import into cell involved in transformation|cellular DNA uptake|cellular DNA import during transformation http://purl.obolibrary.org/obo/GO_0009290 GO:0034229 biolink:BiologicalProcess ethanolamine transport The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine. go-plus.json 2-aminoethanol transport|monoethanolamine transport http://purl.obolibrary.org/obo/GO_0034229 GO:0009291 biolink:BiologicalProcess unidirectional conjugation The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in prokaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0009291 GO:0009292 biolink:BiologicalProcess genetic transfer In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual. go-plus.json genetic exchange http://purl.obolibrary.org/obo/GO_0009292 goslim_pir GO:0009293 biolink:BiologicalProcess transduction The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector. Wikipedia:Transduction_(genetics) go-plus.json http://purl.obolibrary.org/obo/GO_0009293 GO:0009294 biolink:BiologicalProcess DNA mediated transformation The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material. go-plus.json DNA-mediated transformation http://purl.obolibrary.org/obo/GO_0009294 GO:0009295 biolink:CellularComponent nucleoid The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. Wikipedia:Nucleoid go-plus.json http://purl.obolibrary.org/obo/GO_0009295 GO:0009296 biolink:BiologicalProcess obsolete flagellum assembly OBSOLETE. The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers. go-plus.json flagellum biogenesis|flagella assembly|flagellum assembly|flagella biogenesis http://purl.obolibrary.org/obo/GO_0009296 GO:0010275 biolink:BiologicalProcess NAD(P)H dehydrogenase complex assembly The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool. go-plus.json NAD(P)H dehydrogenase complex (plastoquinone) assembly http://purl.obolibrary.org/obo/GO_0010275 GO:0009286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009286 GO:0034220 biolink:BiologicalProcess ion transmembrane transport A process in which an ion is transported across a membrane. go-plus.json ATP hydrolysis coupled ion transmembrane transport|transmembrane ion transport|ion membrane transport http://purl.obolibrary.org/obo/GO_0034220 GO:0010276 biolink:MolecularActivity phytol kinase activity Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+. MetaCyc:RXN-7683|RHEA:38055|EC:2.7.1.182 go-plus.json http://purl.obolibrary.org/obo/GO_0010276 GO:0034221 biolink:BiologicalProcess fungal-type cell wall chitin biosynthetic process The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells. go-plus.json fungal-type cell wall chitin biosynthesis|fungal-type cell wall chitin anabolism|fungal-type cell wall chitin synthesis|fungal-type cell wall chitin formation http://purl.obolibrary.org/obo/GO_0034221 GO:0009287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009287 GO:0034222 biolink:BiologicalProcess regulation of cell wall chitin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall. go-plus.json regulation of cell wall chitin metabolism http://purl.obolibrary.org/obo/GO_0034222 GO:0010273 biolink:BiologicalProcess detoxification of copper ion Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion. go-plus.json http://purl.obolibrary.org/obo/GO_0010273 GO:0009288 biolink:CellularComponent bacterial-type flagellum A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. go-plus.json flagellin-based flagellum http://purl.obolibrary.org/obo/GO_0009288 goslim_pir|goslim_metagenomics GO:0009289 biolink:CellularComponent pilus A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. Wikipedia:Pilus go-plus.json pili|fimbriae|fimbria|fimbrium http://purl.obolibrary.org/obo/GO_0009289 goslim_pir GO:0010274 biolink:BiologicalProcess hydrotropism Growth or movement in a sessile organism toward or away from water, as of the roots of a plant. Wikipedia:Hydrotropism go-plus.json http://purl.obolibrary.org/obo/GO_0010274 GO:0034223 biolink:BiologicalProcess regulation of ascospore wall chitin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin. go-plus.json regulation of ascospore wall chitin anabolism|regulation of ascospore wall chitin synthesis|regulation of ascospore wall chitin formation|regulation of ascospore wall chitin biosynthesis http://purl.obolibrary.org/obo/GO_0034223 CHEBI:62912 biolink:ChemicalSubstance 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62912 GO:0034224 biolink:BiologicalProcess cellular response to zinc ion starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions. go-plus.json cellular response to zinc ion limitation|cellular response to zinc starvation http://purl.obolibrary.org/obo/GO_0034224 GO:0010279 biolink:MolecularActivity indole-3-acetic acid amido synthetase activity Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate. go-plus.json IAA amino acid synthetase activity|IAA amino acid conjugate synthetase activity|IAA amido synthetase activity http://purl.obolibrary.org/obo/GO_0010279 GO:0034225 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions. go-plus.json regulation of transcription from RNA polymerase II promoter in response to zinc ion limitation|regulation of transcription from RNA polymerase II promoter in response to zinc deficiency http://purl.obolibrary.org/obo/GO_0034225 CHEBI:62913 biolink:ChemicalSubstance EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62913 GO:0010277 biolink:MolecularActivity chlorophyllide a oxygenase [overall] activity Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+. RHEA:30359|EC:1.14.13.122 go-plus.json chlorophyllide a:oxygen 7-oxidoreduction activity|chlorophyllide-a oxygenation activity|CAO activity|chlorophyll a oxygenation activity|chlorophyll b synthesis activity|chlorophyll-b synthesis activity http://purl.obolibrary.org/obo/GO_0010277 GO:0034226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034226 GO:0034227 biolink:BiologicalProcess tRNA thio-modification The addition a sulfur atom to a nucleotide in a tRNA molecule. MetaCyc:TRNA-S-TRANSFERASE-RXN|EC:2.8.1.4 go-plus.json tRNA sulfurtransferase activity|tRNA thiolation http://purl.obolibrary.org/obo/GO_0034227 CHEBI:62911 biolink:ChemicalSubstance soyasaponin III(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62911 chebi_ph7_3 GO:0010278 biolink:CellularComponent chloroplast outer membrane translocon The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner. go-plus.json http://purl.obolibrary.org/obo/GO_0010278 CHEBI:62916 biolink:ChemicalSubstance soyasaponin I(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62916 chebi_ph7_3 CHEBI:139069 biolink:ChemicalSubstance 4-hydroxytryptamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139069 chebi_ph7_3 CHEBI:62915 biolink:ChemicalSubstance sialyltransferase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62915 GO:0010271 biolink:BiologicalProcess regulation of chlorophyll catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll. go-plus.json http://purl.obolibrary.org/obo/GO_0010271 CHEBI:139065 biolink:ChemicalSubstance mannosylinositol-1-phosphodihydroceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139065 chebi_ph7_3 GO:0010272 biolink:BiologicalProcess response to silver ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010272 CHEBI:139066 biolink:ChemicalSubstance mannosylinositol-1-phosphophytoceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139066 chebi_ph7_3 CHEBI:139068 biolink:ChemicalSubstance inositol phosphomannosylinositol-1-phosphophytoceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139068 chebi_ph7_3 GO:0010270 biolink:BiologicalProcess photosystem II oxygen evolving complex assembly The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ. go-plus.json OEC (PSII) ASSEMBLY http://purl.obolibrary.org/obo/GO_0010270 CHEBI:62919 biolink:ChemicalSubstance 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62919 GO:0048861 biolink:BiologicalProcess leukemia inhibitory factor signaling pathway Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json leukemia inhibitory factor signalling pathway http://purl.obolibrary.org/obo/GO_0048861 GO:0048862 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048862 GO:0048863 biolink:BiologicalProcess stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. Wikipedia:Stem_cell_differentiation go-plus.json http://purl.obolibrary.org/obo/GO_0048863 GO:0048864 biolink:BiologicalProcess stem cell development The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0048864 GO:0048865 biolink:BiologicalProcess stem cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048865 GO:0048866 biolink:BiologicalProcess stem cell fate specification The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0048866 GO:0048867 biolink:BiologicalProcess stem cell fate determination The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0048867 GO:0048868 biolink:BiologicalProcess pollen tube development The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048868 CHEBI:37958 biolink:ChemicalSubstance dye go-plus.json http://purl.obolibrary.org/obo/CHEBI_37958 GO:0048860 biolink:BiologicalProcess glioblast division The process resulting in the physical partitioning and separation of a glioblast into daughter cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048860 CHEBI:37956 biolink:ChemicalSubstance histamine antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_37956 CHEBI:37957 biolink:ChemicalSubstance histaminergic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_37957 CHEBI:37955 biolink:ChemicalSubstance H1-receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_37955 GO:0048869 biolink:BiologicalProcess cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. go-plus.json http://purl.obolibrary.org/obo/GO_0048869 NCBITaxon:34346 biolink:OrganismalEntity Schizosaccharomycetales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_34346 GO:0048872 biolink:BiologicalProcess homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. go-plus.json homeostasis of cell number|cell population homeostasis http://purl.obolibrary.org/obo/GO_0048872 GO:1902708 biolink:BiologicalProcess response to plumbagin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902708 GO:1902709 biolink:BiologicalProcess cellular response to plumbagin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1902709 GO:0048873 biolink:BiologicalProcess homeostasis of number of cells within a tissue Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0048873 GO:1902706 biolink:BiologicalProcess hexose catabolic process to acetate The chemical reactions and pathways resulting in the breakdown of hexose to acetate. go-plus.json hexose breakdown to acetate|hexose catabolism to acetate|hexose degradation to acetate|acidogenesis http://purl.obolibrary.org/obo/GO_1902706 GO:0048874 biolink:BiologicalProcess host-mediated regulation of intestinal microbiota composition The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut. go-plus.json host-induced regulation of intestinal microbiota composition|homeostasis of number of cells in a free-living population http://purl.obolibrary.org/obo/GO_0048874 GO:1902707 biolink:BiologicalProcess hexose catabolic process to ethanol The chemical reactions and pathways resulting in the breakdown of hexose to ethanol. go-plus.json hexose breakdown to ethanol|hexose catabolism to ethanol|solventogenesis|hexose degradation to ethanol http://purl.obolibrary.org/obo/GO_1902707 GO:0048875 biolink:BiologicalProcess chemical homeostasis within a tissue Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0048875 GO:0048876 biolink:BiologicalProcess chemical homeostasis within retina Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina. go-plus.json http://purl.obolibrary.org/obo/GO_0048876 GO:1902704 biolink:BiologicalProcess hexose catabolic process to acetone The chemical reactions and pathways resulting in the breakdown of hexose to acetone. go-plus.json hexose degradation to acetone|hexose catabolic process to 2-propanone|solventogenesis|hexose breakdown to acetone|hexose catabolism to acetone http://purl.obolibrary.org/obo/GO_1902704 GO:1902705 biolink:BiologicalProcess hexose catabolic process to butyrate The chemical reactions and pathways resulting in the breakdown of hexose to butyrate. go-plus.json hexose catabolism to butyrate|hexose breakdown to butyrate|acidogenesis|hexose degradation to butyrate http://purl.obolibrary.org/obo/GO_1902705 GO:0048877 biolink:BiologicalProcess homeostasis of number of retina cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina. go-plus.json http://purl.obolibrary.org/obo/GO_0048877 GO:1902702 biolink:BiologicalProcess hexose catabolic process to propan-2-ol The chemical reactions and pathways resulting in the breakdown of hexose to propan-2-ol. go-plus.json hexose degradation to propan-2-ol|hexose catabolic process to isopropyl alcohol|solventogenesis|hexose catabolic process to isopropanol|hexose breakdown to propan-2-ol|hexose catabolism to propan-2-ol http://purl.obolibrary.org/obo/GO_1902702 GO:0048878 biolink:BiologicalProcess chemical homeostasis Any biological process involved in the maintenance of an internal steady state of a chemical. go-plus.json http://purl.obolibrary.org/obo/GO_0048878 goslim_drosophila CHEBI:23324 biolink:ChemicalSubstance citrullines go-plus.json http://purl.obolibrary.org/obo/CHEBI_23324 GO:1902703 biolink:BiologicalProcess hexose catabolic process to butan-1-ol The chemical reactions and pathways resulting in the breakdown of hexose to butan-1-ol. go-plus.json hexose catabolism to butan-1-ol|hexose catabolic process to butanol|hexose breakdown to butan-1-ol|solventogenesis|hexose catabolic process to 1-butanol|hexose degradation to butan-1-ol http://purl.obolibrary.org/obo/GO_1902703 GO:1902700 biolink:BiologicalProcess pentose catabolic process to butan-1-ol The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol. go-plus.json pentose catabolic process to butanol|pentose breakdown to butan-1-ol|solventogenesis|pentose catabolic process to 1-butanol|pentose degradation to butan-1-ol|pentose catabolism to butan-1-ol http://purl.obolibrary.org/obo/GO_1902700 GO:1902701 biolink:BiologicalProcess pentose catabolic process to propan-2-ol The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol. go-plus.json pentose degradation to propan-2-ol|pentose catabolic process to isopropyl alcohol|solventogenesis|pentose catabolic process to isopropanol|pentose breakdown to propan-2-ol|pentose catabolism to propan-2-ol http://purl.obolibrary.org/obo/GO_1902701 GO:0048870 biolink:BiologicalProcess cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. go-plus.json cell locomotion|movement of a cell|cell movement http://purl.obolibrary.org/obo/GO_0048870 goslim_drosophila|goslim_generic|goslim_chembl GO:0048871 biolink:BiologicalProcess multicellular organismal homeostasis Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0048871 UBERON:0000170 biolink:AnatomicalEntity pair of lungs The pair of anatomical structures comprised of a left lung and right lung. go-plus.json pulmones|lungs|lungs pair|set of lungs http://purl.obolibrary.org/obo/UBERON_0000170 CHEBI:37963 biolink:ChemicalSubstance pyranone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37963 UBERON:0000171 biolink:AnatomicalEntity respiration organ Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. go-plus.json breathing organ|apparatus respiratorius organ|organ of apparatus respiratorius|organ of respiratory system|respiratory organ|respiratory system organ|gas exchange organ http://purl.obolibrary.org/obo/UBERON_0000171 CHEBI:37962 biolink:ChemicalSubstance adrenergic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_37962 CHEBI:37965 biolink:ChemicalSubstance 2H-pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_37965 chebi_ph7_3 CHEBI:72290 biolink:ChemicalSubstance pyrithiamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72290 chebi_ph7_3 UBERON:0000178 biolink:AnatomicalEntity blood A fluid that is composed of blood plasma and erythrocytes. go-plus.json whole blood|portion of blood|vertebrate blood http://purl.obolibrary.org/obo/UBERON_0000178 UBERON:0000179 biolink:AnatomicalEntity haemolymphatic fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. go-plus.json blood or blood analog|circulating fluid http://purl.obolibrary.org/obo/UBERON_0000179 CHEBI:72293 biolink:ChemicalSubstance monoterpene glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_72293 UBERON:0000174 biolink:AnatomicalEntity excreta A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity go-plus.json excretion|portion of excreted substance|waste substance|excreted substance http://purl.obolibrary.org/obo/UBERON_0000174 GO:0048883 biolink:BiologicalProcess neuromast primordium migration The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop. go-plus.json lateral line primordium migration http://purl.obolibrary.org/obo/GO_0048883 GO:1902719 biolink:BiologicalProcess obsolete extracellular sequestering of copper ion OBSOLETE. The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system. go-plus.json extracellular sequestering of copper ion http://purl.obolibrary.org/obo/GO_1902719 GO:0048884 biolink:BiologicalProcess neuromast development The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals. go-plus.json http://purl.obolibrary.org/obo/GO_0048884 GO:1902717 biolink:BiologicalProcess obsolete sequestering of iron ion OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of iron ion. go-plus.json sequestering of iron ion http://purl.obolibrary.org/obo/GO_1902717 GO:0048885 biolink:BiologicalProcess neuromast deposition The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line. go-plus.json http://purl.obolibrary.org/obo/GO_0048885 GO:0048886 biolink:BiologicalProcess neuromast hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0048886 GO:1902718 biolink:BiologicalProcess obsolete sequestering of copper ion OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of copper ion. go-plus.json sequestering of copper ion http://purl.obolibrary.org/obo/GO_1902718 GO:1902715 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902715 GO:0048887 biolink:BiologicalProcess cupula development The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter. go-plus.json http://purl.obolibrary.org/obo/GO_0048887 GO:1902716 biolink:CellularComponent cell cortex of growing cell tip Any cell cortex that is part of a growing cell tip. go-plus.json cell cortex of growing cell end http://purl.obolibrary.org/obo/GO_1902716 GO:0048888 biolink:BiologicalProcess neuromast mantle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0048888 GO:0048889 biolink:BiologicalProcess neuromast support cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048889 GO:1902713 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902713 GO:1902714 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902714 GO:1902711 biolink:CellularComponent GABA-A receptor complex A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor). go-plus.json http://purl.obolibrary.org/obo/GO_1902711 GO:1902712 biolink:CellularComponent G protein-coupled GABA receptor complex A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2. go-plus.json G-protein coupled GABA receptor complex http://purl.obolibrary.org/obo/GO_1902712 GO:1902710 biolink:CellularComponent GABA receptor complex A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. go-plus.json gamma-aminobutyric acid receptor complex http://purl.obolibrary.org/obo/GO_1902710 GO:0048880 biolink:BiologicalProcess sensory system development The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048880 GO:0048881 biolink:BiologicalProcess mechanosensory lateral line system development The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. go-plus.json LL system development http://purl.obolibrary.org/obo/GO_0048881 GO:0048882 biolink:BiologicalProcess lateral line development The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. go-plus.json LL development http://purl.obolibrary.org/obo/GO_0048882 CHEBI:37930 biolink:ChemicalSubstance phenothiazine antipsychotic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_37930 UBERON:0000160 biolink:AnatomicalEntity intestine Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. go-plus.json intestinal tract|bowel http://purl.obolibrary.org/obo/UBERON_0000160 CHEBI:37931 biolink:ChemicalSubstance 10H-phenothiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37931 chebi_ph7_3 UBERON:0000161 biolink:AnatomicalEntity orifice Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]. go-plus.json ostium|anatomical ostium|anatomical orifice|hilum http://purl.obolibrary.org/obo/UBERON_0000161 UBERON:0000162 biolink:AnatomicalEntity cloaca Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures go-plus.json vent|cloacal chamber http://purl.obolibrary.org/obo/UBERON_0000162 CHEBI:37934 biolink:ChemicalSubstance 1H-phenothiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37934 chebi_ph7_3 CHEBI:37935 biolink:ChemicalSubstance 3H-phenothiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37935 chebi_ph7_3 CHEBI:37932 biolink:ChemicalSubstance phenothiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37932 CHEBI:37933 biolink:ChemicalSubstance 4aH-phenothiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37933 chebi_ph7_3 UBERON:0000167 biolink:AnatomicalEntity oral cavity Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present) go-plus.json bucca|cavity of mouth|buccal cavity http://purl.obolibrary.org/obo/UBERON_0000167 UBERON:0000168 biolink:AnatomicalEntity proximal-distal subdivision of colon A section dividing a colon along a proximal-distal axis. go-plus.json segment of colon http://purl.obolibrary.org/obo/UBERON_0000168 UBERON:0000163 biolink:AnatomicalEntity embryonic cloaca endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]. go-plus.json cloaca http://purl.obolibrary.org/obo/UBERON_0000163 UBERON:0000164 biolink:AnatomicalEntity primitive urogenital sinus the ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females go-plus.json sinus urogenitalis|fetal UGS|UGS|urogenital sinus http://purl.obolibrary.org/obo/UBERON_0000164 UBERON:0000165 biolink:AnatomicalEntity mouth The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). go-plus.json adult mouth|cavital oralis|trophic apparatus|oral region|regio oralis|stomatodaeum|rima oris|stoma|cavum oris|vestibule of mouth|cavitas oris|vestibulum oris|oral vestibule|mouth cavity http://purl.obolibrary.org/obo/UBERON_0000165 UBERON:0000166 biolink:AnatomicalEntity oral opening The orifice that connects the mouth to the exterior of the body. go-plus.json oral part of face|mouth|oral orifice|oral fissure http://purl.obolibrary.org/obo/UBERON_0000166 GO:0048894 biolink:BiologicalProcess efferent axon development in a lateral line nerve The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048894 UBERON:0014790 biolink:AnatomicalEntity lingual septum The lingual septum consists of a vertical layer of fibrous tissue, extending throughout the entire length of the median plane of the tongue, though not quite reaching the dorsum. It is thicker behind than in front, and occasionally contains a small fibrocartilage, about 6 mm. in length. It is well displayed by making a vertical section across the organ. go-plus.json median fibrous septum|tongue septum|septum of tongue|septum of tongue http://purl.obolibrary.org/obo/UBERON_0014790 OBO:uberon/core#site_of biolink:OntologyClass site_of c site_of p if c is the bearer of a disposition that is realized by a process that has p as part site_of go-plus.json capable_of_has_part http://purl.obolibrary.org/obo/uberon/core#site_of GO:0048895 biolink:BiologicalProcess lateral line nerve glial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048895 UBERON:0014791 biolink:AnatomicalEntity musculature of forelimb stylopod Any collection of muscles that is part of the forelimb stylopod region [Automatically generated definition]. go-plus.json musculature of arm|muscle group of arm|arm musculature|set of muscles of arm http://purl.obolibrary.org/obo/UBERON_0014791 GO:0048896 biolink:BiologicalProcess lateral line nerve glial cell migration The movement of a glial cell along the axons in a lateral line nerve. go-plus.json glial cell migration in lateral line nerve http://purl.obolibrary.org/obo/GO_0048896 GO:1902728 biolink:BiologicalProcess positive regulation of growth factor dependent skeletal muscle satellite cell proliferation Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta. go-plus.json http://purl.obolibrary.org/obo/GO_1902728 GO:1902729 biolink:BiologicalProcess negative regulation of proteoglycan biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. go-plus.json negative regulation of proteoglycan anabolism|down-regulation of proteoglycan anabolism|down-regulation of proteoglycan biosynthetic process|down-regulation of proteoglycan biosynthesis|negative regulation of proteoglycan biosynthesis|negative regulation of proteoglycan synthesis|down-regulation of proteoglycan synthesis|negative regulation of proteoglycan formation|down-regulation of proteoglycan formation|inhibition of proteoglycan biosynthetic process|inhibition of proteoglycan biosynthesis|downregulation of proteoglycan anabolism|downregulation of proteoglycan synthesis|down regulation of proteoglycan anabolism|inhibition of proteoglycan anabolism|downregulation of proteoglycan formation|down regulation of proteoglycan synthesis|inhibition of proteoglycan synthesis|down regulation of proteoglycan formation|down regulation of proteoglycan biosynthesis|down regulation of proteoglycan biosynthetic process|inhibition of proteoglycan formation|downregulation of proteoglycan biosynthetic process|downregulation of proteoglycan biosynthesis http://purl.obolibrary.org/obo/GO_1902729 UBERON:0014792 biolink:AnatomicalEntity musculature of pelvic complex Any collection of muscles that is part of a pelvic complex. The pelvic complex comprises the pelvic girdle and the associated limb or fin. go-plus.json musculature of lower limb|musculi membri inferioris|muscles of lower limb http://purl.obolibrary.org/obo/UBERON_0014792 GO:0048897 biolink:BiologicalProcess myelination of lateral line nerve axons The formation of compact myelin sheaths around the axons of a lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048897 GO:1902726 biolink:BiologicalProcess positive regulation of skeletal muscle satellite cell differentiation Any process that activates or increases the frequency, rate or extent of satellite cell differentiation. go-plus.json up regulation of satellite cell differentiation|upregulation of satellite cell differentiation|activation of satellite cell differentiation|up-regulation of satellite cell differentiation http://purl.obolibrary.org/obo/GO_1902726 GO:0048898 biolink:BiologicalProcess anterior lateral line system development The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. go-plus.json ALL system development http://purl.obolibrary.org/obo/GO_0048898 GO:1902727 biolink:BiologicalProcess negative regulation of growth factor dependent skeletal muscle satellite cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta. go-plus.json http://purl.obolibrary.org/obo/GO_1902727 GO:0048899 biolink:BiologicalProcess anterior lateral line development The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. go-plus.json anterior LL development http://purl.obolibrary.org/obo/GO_0048899 GO:1902724 biolink:BiologicalProcess positive regulation of skeletal muscle satellite cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation. go-plus.json upregulation of satellite cell proliferation|up-regulation of satellite cell proliferation|activation of satellite cell proliferation|up regulation of satellite cell proliferation http://purl.obolibrary.org/obo/GO_1902724 GO:1902725 biolink:BiologicalProcess negative regulation of satellite cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation. go-plus.json downregulation of satellite cell differentiation|down regulation of satellite cell differentiation|inhibition of satellite cell differentiation|down-regulation of satellite cell differentiation http://purl.obolibrary.org/obo/GO_1902725 GO:1902722 biolink:BiologicalProcess positive regulation of prolactin secretion Any process that activates or increases the frequency, rate or extent of prolactin secretion. go-plus.json upregulation of prolactin secretion|up regulation of prolactin secretion|activation of prolactin secretion|up-regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_1902722 CHEBI:37949 biolink:ChemicalSubstance azacycloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_37949 GO:1902723 biolink:BiologicalProcess negative regulation of skeletal muscle satellite cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation. go-plus.json inhibition of satellite cell proliferation|down-regulation of satellite cell proliferation|downregulation of satellite cell proliferation|down regulation of satellite cell proliferation http://purl.obolibrary.org/obo/GO_1902723 GO:1902720 biolink:BiologicalProcess obsolete intracellular sequestering of copper ion OBSOLETE. The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system. go-plus.json intracellular sequestering of copper ion http://purl.obolibrary.org/obo/GO_1902720 CHEBI:37947 biolink:ChemicalSubstance benzothiazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_37947 GO:1902721 biolink:BiologicalProcess negative regulation of prolactin secretion Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion. go-plus.json down regulation of prolactin secretion|downregulation of prolactin secretion|down-regulation of prolactin secretion|inhibition of prolactin secretion http://purl.obolibrary.org/obo/GO_1902721 CHEBI:37948 biolink:ChemicalSubstance oxaspiro compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_37948 UBERON:0014793 biolink:AnatomicalEntity musculature of pectoral complex Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin. go-plus.json musculature of upper limb|muscles of upper limb|upper limb musculature|musculi membri superioris|set of muscles of upper limb http://purl.obolibrary.org/obo/UBERON_0014793 GO:0048890 biolink:BiologicalProcess lateral line ganglion development The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear. go-plus.json gLL ganglion development http://purl.obolibrary.org/obo/GO_0048890 UBERON:0014794 biolink:AnatomicalEntity pectoral appendage muscle Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). go-plus.json http://purl.obolibrary.org/obo/UBERON_0014794 GO:0048891 biolink:BiologicalProcess lateral line ganglion neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron. go-plus.json gLL neuron differentiation http://purl.obolibrary.org/obo/GO_0048891 GO:0048892 biolink:BiologicalProcess lateral line nerve development The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. go-plus.json nLL development http://purl.obolibrary.org/obo/GO_0048892 UBERON:0014795 biolink:AnatomicalEntity pelvic appendage muscle Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin). go-plus.json http://purl.obolibrary.org/obo/UBERON_0014795 UBERON:0014796 biolink:AnatomicalEntity common tendinous ring A ring of fibrous tissue surrounding the optic nerve at its entrance at the apex of the orbit. go-plus.json annulus of Zinn|ligament of Zinn|common tendinous ring|annulus tendineus communis|common anular tendon|anulus of Zinn|tendon of Zinn|anulus tendineus communis|anulus tendineus|common annular tendon|anulus tendineus communis http://purl.obolibrary.org/obo/UBERON_0014796 GO:0048893 biolink:BiologicalProcess afferent axon development in lateral line nerve The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0048893 CHEBI:37941 biolink:ChemicalSubstance clopidogrel go-plus.json http://purl.obolibrary.org/obo/CHEBI_37941 chebi_ph7_3 OBO:GOCHE_26155 biolink:OntologyClass substance with plant growth regulator role go-plus.json http://purl.obolibrary.org/obo/GOCHE_26155 3_STAR CHEBI:13997 biolink:ChemicalSubstance citramalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13997 chebi_ph7_3 CHEBI:37942 biolink:ChemicalSubstance thienopyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37942 UBERON:0000151 biolink:AnatomicalEntity pectoral fin Paired fin that is located in the thoracic region of the body. go-plus.json pectoral fins|forefin http://purl.obolibrary.org/obo/UBERON_0000151 CHEBI:37944 biolink:ChemicalSubstance polysaccharide sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37944 UBERON:0000158 biolink:AnatomicalEntity membranous layer go-plus.json membranous organ component|membrane http://purl.obolibrary.org/obo/UBERON_0000158 UBERON:0000159 biolink:AnatomicalEntity anal canal The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus. go-plus.json canalis analis|mesenteron|cloaca|anal canal|pars analis recti|anatomical anal canal|cloacal chamber|anus|anal pad|anal canal viewed anatomically http://purl.obolibrary.org/obo/UBERON_0000159 UBERON:0000152 biolink:AnatomicalEntity pelvic fin Paired fin located in the abdominal position of the body. go-plus.json pelvic fins http://purl.obolibrary.org/obo/UBERON_0000152 UBERON:0000153 biolink:AnatomicalEntity anterior region of body go-plus.json http://purl.obolibrary.org/obo/UBERON_0000153 UBERON:0000154 biolink:AnatomicalEntity posterior region of body go-plus.json http://purl.obolibrary.org/obo/UBERON_0000154 GO:1902739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902739 GO:1902737 biolink:CellularComponent dendritic filopodium A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines. go-plus.json dendrite filopodium http://purl.obolibrary.org/obo/GO_1902737 GO:1902738 biolink:BiologicalProcess regulation of chondrocyte differentiation involved in endochondral bone morphogenesis Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_1902738 GO:1902735 biolink:BiologicalProcess negative regulation of receptor-mediated virion attachment to host cell Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell. go-plus.json downregulation of receptor-mediated virion attachment to host cell|down regulation of receptor-mediated virion attachment to host cell|downregulation of virion attachment, binding of host cell surface receptor|inhibition of receptor-mediated virion attachment to host cell|down regulation of virion attachment, binding of host cell surface receptor|inhibition of virion attachment, binding of host cell surface receptor|down-regulation of receptor-mediated virion attachment to host cell|down-regulation of virion attachment, binding of host cell surface receptor|negative regulation of virion attachment, binding of host cell surface receptor http://purl.obolibrary.org/obo/GO_1902735 GO:1902736 biolink:BiologicalProcess positive regulation of receptor-mediated virion attachment to host cell Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell. go-plus.json positive regulation of virion attachment, binding of host cell surface receptor|up regulation of virion attachment, binding of host cell surface receptor|upregulation of receptor-mediated virion attachment to host cell|upregulation of virion attachment, binding of host cell surface receptor|up-regulation of receptor-mediated virion attachment to host cell|activation of receptor-mediated virion attachment to host cell|up-regulation of virion attachment, binding of host cell surface receptor|activation of virion attachment, binding of host cell surface receptor|up regulation of receptor-mediated virion attachment to host cell http://purl.obolibrary.org/obo/GO_1902736 GO:1902733 biolink:BiologicalProcess regulation of growth plate cartilage chondrocyte differentiation Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_1902733 GO:1902734 biolink:BiologicalProcess regulation of receptor-mediated virion attachment to host cell Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell. go-plus.json regulation of virion attachment, binding of host cell surface receptor http://purl.obolibrary.org/obo/GO_1902734 GO:1902731 biolink:BiologicalProcess negative regulation of chondrocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json inhibition of chondrocyte proliferation|negative regulation of chondrocyte cell proliferation|down-regulation of chondrocyte cell proliferation|downregulation of cartilage cell proliferation|down regulation of cartilage cell proliferation|inhibition of cartilage cell proliferation|down regulation of chondrocyte proliferation|downregulation of chondrocyte cell proliferation|downregulation of chondrocyte proliferation|down regulation of chondrocyte cell proliferation|inhibition of chondrocyte cell proliferation|down-regulation of chondrocyte proliferation|down-regulation of cartilage cell proliferation|negative regulation of cartilage cell proliferation http://purl.obolibrary.org/obo/GO_1902731 CHEBI:37914 biolink:ChemicalSubstance 27-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37914 GO:1902732 biolink:BiologicalProcess positive regulation of chondrocyte proliferation Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json up-regulation of chondrocyte cell proliferation|activation of chondrocyte cell proliferation|positive regulation of cartilage cell proliferation|up-regulation of chondrocyte proliferation|up regulation of cartilage cell proliferation|positive regulation of chondrocyte cell proliferation|up regulation of chondrocyte cell proliferation|upregulation of chondrocyte proliferation|upregulation of cartilage cell proliferation|up regulation of chondrocyte proliferation|upregulation of chondrocyte cell proliferation|activation of chondrocyte proliferation|up-regulation of cartilage cell proliferation|activation of cartilage cell proliferation http://purl.obolibrary.org/obo/GO_1902732 GO:1902730 biolink:BiologicalProcess positive regulation of proteoglycan biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. go-plus.json upregulation of proteoglycan synthesis|upregulation of proteoglycan formation|up-regulation of proteoglycan anabolism|activation of proteoglycan anabolism|up regulation of proteoglycan biosynthetic process|up regulation of proteoglycan biosynthesis|up-regulation of proteoglycan synthesis|activation of proteoglycan biosynthesis|activation of proteoglycan biosynthetic process|positive regulation of proteoglycan biosynthesis|activation of proteoglycan synthesis|up-regulation of proteoglycan formation|activation of proteoglycan formation|positive regulation of proteoglycan anabolism|up regulation of proteoglycan anabolism|positive regulation of proteoglycan synthesis|up-regulation of proteoglycan biosynthetic process|up-regulation of proteoglycan biosynthesis|up regulation of proteoglycan synthesis|positive regulation of proteoglycan formation|up regulation of proteoglycan formation|upregulation of proteoglycan anabolism|upregulation of proteoglycan biosynthetic process|upregulation of proteoglycan biosynthesis http://purl.obolibrary.org/obo/GO_1902730 CHEBI:37919 biolink:ChemicalSubstance aryl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37919 CHEBI:13941 biolink:ChemicalSubstance carbamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13941 chebi_ph7_3 CHEBI:37912 biolink:ChemicalSubstance hydroxycoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_37912 CHEBI:37911 biolink:ChemicalSubstance indane go-plus.json http://purl.obolibrary.org/obo/CHEBI_37911 chebi_ph7_3 GO:1902748 biolink:BiologicalProcess positive regulation of lens fiber cell differentiation Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation. go-plus.json up regulation of lens fibre cell differentiation|activation of lens fibre cell differentiation|positive regulation of lens fibre cell differentiation|up-regulation of lens fiber cell differentiation|up-regulation of lens fibre cell differentiation|upregulation of lens fiber cell differentiation|upregulation of lens fibre cell differentiation|up regulation of lens fiber cell differentiation|activation of lens fiber cell differentiation http://purl.obolibrary.org/obo/GO_1902748 GO:1902749 biolink:BiologicalProcess regulation of cell cycle G2/M phase transition Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1902749 GO:1902746 biolink:BiologicalProcess regulation of lens fiber cell differentiation Any process that modulates the frequency, rate or extent of lens fiber cell differentiation. go-plus.json regulation of lens fibre cell differentiation http://purl.obolibrary.org/obo/GO_1902746 GO:1902747 biolink:BiologicalProcess negative regulation of lens fiber cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation. go-plus.json down-regulation of lens fiber cell differentiation|negative regulation of lens fibre cell differentiation|down-regulation of lens fibre cell differentiation|inhibition of lens fiber cell differentiation|inhibition of lens fibre cell differentiation|down regulation of lens fiber cell differentiation|downregulation of lens fiber cell differentiation|down regulation of lens fibre cell differentiation|downregulation of lens fibre cell differentiation http://purl.obolibrary.org/obo/GO_1902747 GO:1902744 biolink:BiologicalProcess negative regulation of lamellipodium organization Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization. go-plus.json down-regulation of lamellipodium organization|downregulation of lamellipodium organization|down regulation of lamellipodium organization|inhibition of lamellipodium organization http://purl.obolibrary.org/obo/GO_1902744 GO:1902745 biolink:BiologicalProcess positive regulation of lamellipodium organization Any process that activates or increases the frequency, rate or extent of lamellipodium organization. go-plus.json activation of lamellipodium organization|up regulation of lamellipodium organization|upregulation of lamellipodium organization|up-regulation of lamellipodium organization http://purl.obolibrary.org/obo/GO_1902745 GO:1902742 biolink:BiologicalProcess apoptotic process involved in development Any apoptotic process that is involved in anatomical structure development. go-plus.json type I programmed cell death involved in development of an anatomical structure|apoptosis involved in development of an anatomical structure|apoptosis activator activity involved in development of an anatomical structure|induction of apoptosis involved in development of an anatomical structure|activation of apoptosis involved in development of an anatomical structure|programmed cell death by apoptosis involved in anatomical structure development|commitment to apoptosis involved in anatomical structure development|apoptotic programmed cell death involved in development of an anatomical structure|apoptotic process involved in development of an anatomical structure|apoptotic cell death involved in development of an anatomical structure|signaling (initiator) caspase activity involved in anatomical structure development|apoptotic program involved in anatomical structure development|induction of apoptosis by p53 involved in anatomical structure development|apoptotic process involved in anatomical structure development|apoptosis signaling involved in anatomical structure development|programmed cell death by apoptosis involved in development of an anatomical structure|commitment to apoptosis involved in development of an anatomical structure|type I programmed cell death involved in anatomical structure development|signaling (initiator) caspase activity involved in development of an anatomical structure|apoptosis activator activity involved in anatomical structure development|apoptosis involved in anatomical structure development|induction of apoptosis involved in anatomical structure development|apoptotic program involved in development of an anatomical structure|induction of apoptosis by p53 involved in development of an anatomical structure|activation of apoptosis involved in anatomical structure development|apoptotic programmed cell death involved in anatomical structure development|apoptotic cell death involved in anatomical structure development|apoptosis signaling involved in development of an anatomical structure http://purl.obolibrary.org/obo/GO_1902742 GO:1902743 biolink:BiologicalProcess regulation of lamellipodium organization Any process that modulates the frequency, rate or extent of lamellipodium organization. go-plus.json http://purl.obolibrary.org/obo/GO_1902743 GO:1902740 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902740 GO:1902741 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902741 CHEBI:37921 biolink:ChemicalSubstance pyridazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_37921 GO:1902759 biolink:BiologicalProcess Mo(VI)-molybdopterin cytosine dinucleotide metabolic process The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide. go-plus.json Mo(VI)-molybdopterin cytosine dinucleotide metabolism http://purl.obolibrary.org/obo/GO_1902759 GO:1902757 biolink:BiologicalProcess bis(molybdopterin guanine dinucleotide)molybdenum metabolic process The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum. go-plus.json bis(molybdopterin guanine dinucleotide)molybdenum metabolism http://purl.obolibrary.org/obo/GO_1902757 GO:1902758 biolink:BiologicalProcess bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum. MetaCyc:PWY-5964 go-plus.json bis(molybdopterin guanine dinucleotide)molybdenum biosynthesis|bis(molybdopterin guanine dinucleotide)molybdenum anabolism|bis(molybdopterin guanine dinucleotide)molybdenum synthesis|bis(molybdopterin guanine dinucleotide)molybdenum formation|bis-Mo-molybdopterin-guanine dinucleotide cofactor biosynthetic process http://purl.obolibrary.org/obo/GO_1902758 GO:1902755 biolink:BiologicalProcess sulfurated eukaryotic molybdenum cofactor(2-) metabolic process The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-). go-plus.json sulfurated eukaryotic molybdenum cofactor(2-) metabolism http://purl.obolibrary.org/obo/GO_1902755 GO:1902756 biolink:BiologicalProcess sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-). Reactome:R-HSA-947581|MetaCyc:PWY-6476 go-plus.json sulfurated eukaryotic molybdenum cofactor(2-) anabolism|sulfurated eukaryotic molybdenum cofactor(2-) synthesis|sulfurated eukaryotic molybdenum cofactor(2-) formation|sulfurated eukaryotic molybdenum cofactor(2-) biosynthesis http://purl.obolibrary.org/obo/GO_1902756 GO:1902753 biolink:BiologicalProcess negative regulation of renal amino acid absorption Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption. go-plus.json down regulation of renal amino acid absorption|downregulation of renal amino acid absorption|down-regulation of renal amino acid absorption|inhibition of renal amino acid absorption http://purl.obolibrary.org/obo/GO_1902753 GO:1902754 biolink:BiologicalProcess positive regulation of renal amino acid absorption Any process that activates or increases the frequency, rate or extent of renal amino acid absorption. go-plus.json upregulation of renal amino acid absorption|up regulation of renal amino acid absorption|activation of renal amino acid absorption|up-regulation of renal amino acid absorption http://purl.obolibrary.org/obo/GO_1902754 GO:1902751 biolink:BiologicalProcess positive regulation of cell cycle G2/M phase transition Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. go-plus.json upregulation of cell cycle G2/M phase transition|activation of cell cycle G2/M phase transition|up-regulation of cell cycle G2/M phase transition|up regulation of cell cycle G2/M phase transition http://purl.obolibrary.org/obo/GO_1902751 GO:1902752 biolink:BiologicalProcess regulation of renal amino acid absorption Any process that modulates the frequency, rate or extent of renal amino acid absorption. go-plus.json http://purl.obolibrary.org/obo/GO_1902752 GO:1902750 biolink:BiologicalProcess negative regulation of cell cycle G2/M phase transition Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. go-plus.json down regulation of cell cycle G2/M phase transition|inhibition of cell cycle G2/M phase transition|down-regulation of cell cycle G2/M phase transition|downregulation of cell cycle G2/M phase transition http://purl.obolibrary.org/obo/GO_1902750 NCBITaxon:34353 biolink:OrganismalEntity Dipodascaceae go-plus.json anamorphic Dipodascaceae http://purl.obolibrary.org/obo/NCBITaxon_34353 GO:1902768 biolink:BiologicalProcess isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate. go-plus.json isoprenoid formation via 1-deoxy-D-xylulose 5-phosphate|isoprenoid synthesis via 1-deoxy-D-xylulose 5-phosphate|isoprenoid anabolism via 1-deoxy-D-xylulose 5-phosphate|isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate http://purl.obolibrary.org/obo/GO_1902768 GO:1902769 biolink:BiologicalProcess regulation of choline O-acetyltransferase activity Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity. go-plus.json regulation of CHOACTase activity|regulation of choline acetylase activity|regulation of acetyl-CoA:choline O-acetyltransferase activity|regulation of choline acetyltransferase activity http://purl.obolibrary.org/obo/GO_1902769 GO:1902766 biolink:BiologicalProcess skeletal muscle satellite cell migration The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells. go-plus.json http://purl.obolibrary.org/obo/GO_1902766 GO:1902767 biolink:BiologicalProcess isoprenoid biosynthetic process via mevalonate The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate. go-plus.json isoprenoid formation via mevalonate|isoprenoid synthesis via mevalonate|isoprenoid anabolism via mevalonate|isoprenoid biosynthesis via mevalonate http://purl.obolibrary.org/obo/GO_1902767 GO:1902764 biolink:BiologicalProcess positive regulation of embryonic skeletal joint development Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development. go-plus.json upregulation of embryonic skeletal joint development|up-regulation of embryonic skeletal joint development|activation of embryonic skeletal joint development|up regulation of embryonic skeletal joint development http://purl.obolibrary.org/obo/GO_1902764 CHEBI:37903 biolink:ChemicalSubstance lysyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37903 GO:1902765 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902765 CHEBI:37909 biolink:ChemicalSubstance oligosaccharide sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37909 CHEBI:13956 biolink:ChemicalSubstance ceramide 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13956 GO:1902762 biolink:BiologicalProcess regulation of embryonic skeletal joint development Any process that modulates the frequency, rate or extent of embryonic skeletal joint development. go-plus.json http://purl.obolibrary.org/obo/GO_1902762 NCBITaxon:178306 biolink:OrganismalEntity Pyrobaculum aerophilum str. IM2 go-plus.json Pyrobaculum aerophilum strain IM2|Pyrobaculum aerophilum IM2 http://purl.obolibrary.org/obo/NCBITaxon_178306 GO:1902763 biolink:BiologicalProcess negative regulation of embryonic skeletal joint development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development. go-plus.json downregulation of embryonic skeletal joint development|down regulation of embryonic skeletal joint development|inhibition of embryonic skeletal joint development|down-regulation of embryonic skeletal joint development http://purl.obolibrary.org/obo/GO_1902763 GO:1902760 biolink:BiologicalProcess Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide. MetaCyc:PWY-6476 go-plus.json Mo(VI)-molybdopterin cytosine dinucleotide anabolism|Mo(VI)-molybdopterin cytosine dinucleotide synthesis|Mo-molybdopterin-cytosine-dinucleotide cofactor biosynthetic process|Mo(VI)-molybdopterin cytosine dinucleotide formation|Mo(VI)-molybdopterin cytosine dinucleotide biosynthesis http://purl.obolibrary.org/obo/GO_1902760 GO:1902761 biolink:BiologicalProcess positive regulation of chondrocyte development Any process that activates or increases the frequency, rate or extent of chondrocyte development. go-plus.json up-regulation of chondrocyte development|upregulation of chondrocyte development|up regulation of chondrocyte development|activation of chondrocyte development http://purl.obolibrary.org/obo/GO_1902761 GO:1902770 biolink:BiologicalProcess negative regulation of choline O-acetyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity. go-plus.json downregulation of acetyl-CoA:choline O-acetyltransferase activity|down-regulation of CHOACTase activity|downregulation of choline acetyltransferase activity|negative regulation of CHOACTase activity|down-regulation of choline acetylase activity|downregulation of choline O-acetyltransferase activity|negative regulation of choline acetylase activity|down regulation of choline acetyltransferase activity|down regulation of choline O-acetyltransferase activity|inhibition of choline acetyltransferase activity|down-regulation of acetyl-CoA:choline O-acetyltransferase activity|negative regulation of acetyl-CoA:choline O-acetyltransferase activity|inhibition of choline O-acetyltransferase activity|downregulation of CHOACTase activity|downregulation of choline acetylase activity|down regulation of CHOACTase activity|inhibition of acetyl-CoA:choline O-acetyltransferase activity|down regulation of choline acetylase activity|inhibition of CHOACTase activity|inhibition of choline acetylase activity|down-regulation of choline acetyltransferase activity|negative regulation of choline acetyltransferase activity|down-regulation of choline O-acetyltransferase activity|down regulation of acetyl-CoA:choline O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_1902770 CHEBI:37902 biolink:ChemicalSubstance methionyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37902 CHEBI:37900 biolink:ChemicalSubstance threonyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37900 OBO:GOCHE_26115 biolink:OntologyClass substance with phytoalexin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_26115 3_STAR GO:0010404 biolink:BiologicalProcess cell wall hydroxyproline-rich glycoprotein metabolic process The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates. go-plus.json cell wall hydroxyproline-rich glycoprotein metabolism http://purl.obolibrary.org/obo/GO_0010404 GO:0010405 biolink:BiologicalProcess arabinogalactan protein metabolic process The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures. go-plus.json arabinogalactan protein metabolism http://purl.obolibrary.org/obo/GO_0010405 GO:0010402 biolink:BiologicalProcess pectic arabinan metabolic process The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I. go-plus.json pectic arabinan metabolism http://purl.obolibrary.org/obo/GO_0010402 GO:0010403 biolink:BiologicalProcess pectic arabinogalactan I metabolic process The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I. go-plus.json pectic arabinogalactan I metabolism http://purl.obolibrary.org/obo/GO_0010403 GO:0010408 biolink:BiologicalProcess fasciclin-like arabinogalactan protein metabolic process The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain. go-plus.json fasciclin-like arabinogalactan protein metabolism http://purl.obolibrary.org/obo/GO_0010408 GO:0010409 biolink:BiologicalProcess extensin metabolic process The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated. go-plus.json extensin metabolism http://purl.obolibrary.org/obo/GO_0010409 GO:0010406 biolink:BiologicalProcess classical arabinogalactan protein metabolic process The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored. go-plus.json classical-arabinogalactan protein metabolism http://purl.obolibrary.org/obo/GO_0010406 GO:0010407 biolink:BiologicalProcess non-classical arabinogalactan protein metabolic process The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains. go-plus.json non-classical arabinogalactan protein metabolism http://purl.obolibrary.org/obo/GO_0010407 NCBITaxon:418459 biolink:OrganismalEntity Puccinia graminis f. sp. tritici CRL 75-36-700-3 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_418459 GO:0009410 biolink:BiologicalProcess response to xenobiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json drug resistance|drug susceptibility/resistance|response to drug http://purl.obolibrary.org/obo/GO_0009410 goslim_candida CHEBI:62885 biolink:ChemicalSubstance adenosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_62885 chebi_ph7_3 GO:0009411 biolink:BiologicalProcess response to UV Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. go-plus.json response to ultraviolet light stimulus|response to UV light stimulus|response to ultraviolet radiation stimulus|response to UV radiation stimulus http://purl.obolibrary.org/obo/GO_0009411 GO:0010400 biolink:BiologicalProcess rhamnogalacturonan I side chain metabolic process The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I. go-plus.json rhamnogalacturonan I side chain metabolism http://purl.obolibrary.org/obo/GO_0010400 GO:0009412 biolink:BiologicalProcess obsolete response to heavy metal OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. go-plus.json response to heavy metal http://purl.obolibrary.org/obo/GO_0009412 GO:0010401 biolink:BiologicalProcess pectic galactan metabolic process The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I. go-plus.json pectic galactan metabolism http://purl.obolibrary.org/obo/GO_0010401 GO:0009413 biolink:BiologicalProcess response to flooding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water. go-plus.json http://purl.obolibrary.org/obo/GO_0009413 GO:0009414 biolink:BiologicalProcess response to water deprivation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. go-plus.json response to drought|response to dehydration|drought tolerance|response to thirst http://purl.obolibrary.org/obo/GO_0009414 CHEBI:62889 biolink:ChemicalSubstance organic diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62889 GO:0009415 biolink:BiologicalProcess response to water Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. go-plus.json response to water stimulus http://purl.obolibrary.org/obo/GO_0009415 GO:0009416 biolink:BiologicalProcess response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. go-plus.json http://purl.obolibrary.org/obo/GO_0009416 goslim_plant GO:0009417 biolink:CellularComponent obsolete fimbrin OBSOLETE. A class of proteins that are the subunit components of fimbria. go-plus.json fimbrin http://purl.obolibrary.org/obo/GO_0009417 GO:0009418 biolink:CellularComponent pilus shaft The long, slender, mid section of a pilus. go-plus.json fimbrial shaft http://purl.obolibrary.org/obo/GO_0009418 GO:0009419 biolink:CellularComponent pilus tip The pointed extremity furthest from the cell of a pilus. go-plus.json fimbrial tip http://purl.obolibrary.org/obo/GO_0009419 GO:0010415 biolink:BiologicalProcess unsubstituted mannan metabolic process The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units. go-plus.json unsubstituted mannan metabolism http://purl.obolibrary.org/obo/GO_0010415 GO:0010416 biolink:BiologicalProcess arabinoxylan-containing compound metabolic process The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units. go-plus.json arabinoxylan metabolism|arabinoxylan metabolic process http://purl.obolibrary.org/obo/GO_0010416 CHEBI:62890 biolink:ChemicalSubstance 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62890 chebi_ph7_3 GO:0010413 biolink:BiologicalProcess glucuronoxylan metabolic process The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units. go-plus.json glucuronoxylan metabolism http://purl.obolibrary.org/obo/GO_0010413 GO:0010414 biolink:BiologicalProcess glucuronoarabinoxylan metabolic process The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units. go-plus.json glucuronoarabinoxylan metabolism http://purl.obolibrary.org/obo/GO_0010414 GO:0010419 biolink:BiologicalProcess rhamnogalacturonan II side chain metabolic process The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively. go-plus.json rhamnogalacturonan II side chain metabolism http://purl.obolibrary.org/obo/GO_0010419 CHEBI:62894 biolink:ChemicalSubstance organic triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62894 CHEBI:23286 biolink:ChemicalSubstance cis-3,4-dihydrophenanthrene-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23286 GO:0010417 biolink:BiologicalProcess glucuronoxylan biosynthetic process The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues. go-plus.json glucuronoxylan synthesis|glucuronoxylan formation|glucuronoxylan biosynthesis|glucuronoxylan anabolism http://purl.obolibrary.org/obo/GO_0010417 GO:0010418 biolink:BiologicalProcess rhamnogalacturonan II backbone metabolic process The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues. go-plus.json rhamnogalacturonan II backbone metabolism http://purl.obolibrary.org/obo/GO_0010418 CHEBI:62898 biolink:ChemicalSubstance isopentenyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62898 chebi_ph7_3 GO:0009420 biolink:CellularComponent bacterial-type flagellum filament The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller. go-plus.json flagellar filament|flagellin-based flagellum filament http://purl.obolibrary.org/obo/GO_0009420 GO:0009421 biolink:CellularComponent bacterial-type flagellum filament cap The proteinaceous structure at the distal tip of the bacterial-type flagellar filament. go-plus.json flagellar filament cap|flagellin-based flagellum filament cap http://purl.obolibrary.org/obo/GO_0009421 GO:0010411 biolink:BiologicalProcess xyloglucan metabolic process The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants. go-plus.json xyloglucan metabolism http://purl.obolibrary.org/obo/GO_0010411 GO:0009422 biolink:CellularComponent bacterial-type flagellum hook-filament junction The region of the bacterial-type flagellum where the hook and filament meet. go-plus.json flagellar hook-filament junction http://purl.obolibrary.org/obo/GO_0009422 GO:0009423 biolink:BiologicalProcess chorismate biosynthetic process The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds. MetaCyc:ARO-PWY go-plus.json chorismate anabolism|chorismate synthesis|shikimate anabolism|chorismate formation|shikimate synthesis|shikimate pathway|chorismate biosynthesis|shikimate biosynthesis|shikimate biosynthetic process http://purl.obolibrary.org/obo/GO_0009423 GO:0010412 biolink:BiologicalProcess mannan metabolic process The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units. go-plus.json mannan metabolism http://purl.obolibrary.org/obo/GO_0010412 GO:0009424 biolink:CellularComponent bacterial-type flagellum hook The portion of the bacterial-type flagellum that connects the filament to the basal body. go-plus.json flagellin-based flagellum hook|flagellar hook http://purl.obolibrary.org/obo/GO_0009424 CHEBI:62899 biolink:ChemicalSubstance (R,Z)- 2-carboxylato-4-methyl-5-[(2-phosphonatooxy)ethylidene]-2,5-dihydrothiazole(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62899 chebi_ph7_3 GO:0009425 biolink:CellularComponent bacterial-type flagellum basal body One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor. go-plus.json flagellin-based flagellum basal body|flagellar basal body http://purl.obolibrary.org/obo/GO_0009425 GO:0010410 biolink:BiologicalProcess hemicellulose metabolic process The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present. go-plus.json hemicellulose metabolism http://purl.obolibrary.org/obo/GO_0010410 GO:0009426 biolink:CellularComponent bacterial-type flagellum basal body, distal rod The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes. go-plus.json flagellar basal body, distal rod|flagellin-based flagellum basal body, distal rod http://purl.obolibrary.org/obo/GO_0009426 GO:0009427 biolink:CellularComponent bacterial-type flagellum basal body, distal rod, L ring One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane. go-plus.json flagellar basal body, distal rod, L ring|flagellin-based flagellum basal body, distal rod, L ring http://purl.obolibrary.org/obo/GO_0009427 GO:0009428 biolink:CellularComponent bacterial-type flagellum basal body, distal rod, P ring One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer. go-plus.json flagellin-based flagellum basal body, distal rod, P ring|flagellar basal body, distal rod, P ring http://purl.obolibrary.org/obo/GO_0009428 GO:0009429 biolink:CellularComponent bacterial-type flagellum basal body, proximal rod The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor. go-plus.json flagellar basal body, proximal rod|flagellin-based flagellum basal body, proximal rod http://purl.obolibrary.org/obo/GO_0009429 CHEBI:23252 biolink:ChemicalSubstance cinnamic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_23252 CHEBI:37897 biolink:ChemicalSubstance valyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37897 CHEBI:37898 biolink:ChemicalSubstance tyrosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37898 CHEBI:37890 biolink:ChemicalSubstance alpha-adrenergic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_37890 CHEBI:47214 biolink:ChemicalSubstance (23S)-23,25-dihydroxycalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47214 chebi_ph7_3 GO:0009400 biolink:MolecularActivity obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. go-plus.json receptor signaling protein serine/threonine phosphatase activity|receptor signalling protein serine/threonine phosphatase activity http://purl.obolibrary.org/obo/GO_0009400 GO:0009401 biolink:BiologicalProcess phosphoenolpyruvate-dependent sugar phosphotransferase system The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC. go-plus.json PTS system http://purl.obolibrary.org/obo/GO_0009401 GO:0009402 biolink:BiologicalProcess obsolete toxin resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json toxin resistance http://purl.obolibrary.org/obo/GO_0009402 GO:0009403 biolink:BiologicalProcess toxin biosynthetic process The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. go-plus.json toxin formation|toxin biosynthesis|toxin anabolism|toxin synthesis http://purl.obolibrary.org/obo/GO_0009403 goslim_metagenomics GO:0009404 biolink:BiologicalProcess toxin metabolic process The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. go-plus.json toxin metabolism http://purl.obolibrary.org/obo/GO_0009404 goslim_pir|goslim_aspergillus GO:0009405 biolink:BiologicalProcess obsolete pathogenesis OBSOLETE. The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism. go-plus.json virulence http://purl.obolibrary.org/obo/GO_0009405 goslim_chembl|goslim_candida|goslim_aspergillus|goslim_metagenomics GO:0009406 biolink:BiologicalProcess obsolete virulence OBSOLETE. (Was not defined before being made obsolete). go-plus.json virulence http://purl.obolibrary.org/obo/GO_0009406 GO:0009407 biolink:BiologicalProcess toxin catabolic process The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. go-plus.json toxin catabolism|toxin degradation|toxin breakdown http://purl.obolibrary.org/obo/GO_0009407 GO:0009408 biolink:BiologicalProcess response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. go-plus.json response to heat shock http://purl.obolibrary.org/obo/GO_0009408 goslim_yeast GO:0009409 biolink:BiologicalProcess response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. go-plus.json freezing tolerance http://purl.obolibrary.org/obo/GO_0009409 CHEBI:23232 biolink:ChemicalSubstance chromenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23232 CHEBI:23238 biolink:ChemicalSubstance chromones go-plus.json http://purl.obolibrary.org/obo/CHEBI_23238 CHEBI:23239 biolink:ChemicalSubstance chromopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23239 CHEBI:23237 biolink:ChemicalSubstance chromium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_23237 CHEBI:23230 biolink:ChemicalSubstance chromanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23230 CHEBI:37875 biolink:ChemicalSubstance acyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37875 CHEBI:37876 biolink:ChemicalSubstance O-acylglucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37876 CHEBI:37878 biolink:ChemicalSubstance glucosamine sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37878 CHEBI:23245 biolink:ChemicalSubstance cinnamaldehydes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23245 CHEBI:23243 biolink:ChemicalSubstance cineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_23243 CHEBI:23247 biolink:ChemicalSubstance cinnamamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_23247 CHEBI:23248 biolink:ChemicalSubstance cinnamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23248 chebi_ph7_3 CHEBI:23240 biolink:ChemicalSubstance chromophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_23240 CHEBI:37886 biolink:ChemicalSubstance adrenergic agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_37886 CHEBI:37887 biolink:ChemicalSubstance adrenergic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_37887 CHEBI:37888 biolink:ChemicalSubstance (1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37888 CHEBI:37889 biolink:ChemicalSubstance (1S,6R)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37889 CHEBI:541975 biolink:ChemicalSubstance epiandrosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_541975 chebi_ph7_3 CHEBI:23213 biolink:ChemicalSubstance choline ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_23213 CHEBI:23216 biolink:ChemicalSubstance choline sulfates go-plus.json http://purl.obolibrary.org/obo/CHEBI_23216 CHEBI:23217 biolink:ChemicalSubstance cholines go-plus.json http://purl.obolibrary.org/obo/CHEBI_23217 UBERON:0014401 biolink:AnatomicalEntity renal venous blood vessel Any member of the network of tubes that return blood from the renal tissues to the systemic circulation. go-plus.json kidney venous blood vessel|kidney venous system|venous blood vessel of kidney http://purl.obolibrary.org/obo/UBERON_0014401 UBERON:0014402 biolink:AnatomicalEntity sex-specific anatomical structure A part of the body present only in a specific gender. go-plus.json gender-specific|sex-specific|gender-specific anatomical structure http://purl.obolibrary.org/obo/UBERON_0014402 UBERON:0014403 biolink:AnatomicalEntity male anatomical structure A part of the body present only in males. go-plus.json male-specific structure|male-specific http://purl.obolibrary.org/obo/UBERON_0014403 CHEBI:37859 biolink:ChemicalSubstance sulfenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37859 UBERON:0014404 biolink:AnatomicalEntity female anatomical structure A part of the body present only in females. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014404 UBERON:0014400 biolink:AnatomicalEntity hepatic sinusoidal space A sinusoidal space that is part of a hepatic sinusoid. go-plus.json lumen of hepatic sinusoid http://purl.obolibrary.org/obo/UBERON_0014400 CHEBI:37852 biolink:ChemicalSubstance organoammonium sulfate salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_37852 CHEBI:37858 biolink:ChemicalSubstance sulfenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37858 chebi_ph7_3 CHEBI:23218 biolink:ChemicalSubstance choloyl-CoAs go-plus.json http://purl.obolibrary.org/obo/CHEBI_23218 CHEBI:23219 biolink:ChemicalSubstance bile acid taurine conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23219 CHEBI:37864 biolink:ChemicalSubstance thioperoxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37864 CHEBI:37862 biolink:ChemicalSubstance O-sulfoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37862 CHEBI:37863 biolink:ChemicalSubstance chalcoperoxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37863 CHEBI:37868 biolink:ChemicalSubstance octanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37868 CHEBI:23229 biolink:ChemicalSubstance chromanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23229 CHEBI:37861 biolink:ChemicalSubstance nucleotide-sugar sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37861 GO:0034459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034459 GO:0009495 biolink:MolecularActivity obsolete thioredoxin-like 2Fe-2S ferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json thioredoxin-like 2Fe-2S ferredoxin http://purl.obolibrary.org/obo/GO_0009495 GO:0010484 biolink:MolecularActivity H3 histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3. go-plus.json http://purl.obolibrary.org/obo/GO_0010484 GO:0034451 biolink:CellularComponent centriolar satellite A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0034451 GO:0009496 biolink:MolecularActivity plastoquinol--plastocyanin reductase activity Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane. RHEA:22148|EC:7.1.1.6|MetaCyc:PLASTOQUINOL--PLASTOCYANIN-REDUCTASE-RXN|KEGG_REACTION:R03817 go-plus.json plastoquinol/plastocyanin oxidoreductase activity|cytochrome b6f complex activity|cytochrome b6f|plastoquinol-plastocyanin reductase activity|plastoquinol:oxidized-plastocyanin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0009496 GO:0010485 biolink:MolecularActivity H4 histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4. go-plus.json http://purl.obolibrary.org/obo/GO_0010485 GO:0034452 biolink:MolecularActivity dynactin binding Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0034452 GO:0009497 biolink:MolecularActivity obsolete 3Fe-4S/4Fe-4S electron transfer carrier OBSOLETE. (Was not defined before being made obsolete). go-plus.json 3Fe-4S/4Fe-4S electron transfer carrier http://purl.obolibrary.org/obo/GO_0009497 GO:0034453 biolink:BiologicalProcess microtubule anchoring Any process in which a microtubule is maintained in a specific location in a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0034453 GO:0010482 biolink:BiologicalProcess regulation of epidermal cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. go-plus.json regulation of hypodermal cell division http://purl.obolibrary.org/obo/GO_0010482 GO:0009498 biolink:MolecularActivity obsolete bacterial-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json bacterial-type ferredoxin http://purl.obolibrary.org/obo/GO_0009498 GO:0010483 biolink:BiologicalProcess pollen tube reception Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010483 GO:0034454 biolink:BiologicalProcess microtubule anchoring at centrosome Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0034454 GO:0009499 biolink:MolecularActivity obsolete monocluster bacterial-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json monocluster bacterial-type ferredoxin http://purl.obolibrary.org/obo/GO_0009499 GO:0010488 biolink:MolecularActivity UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP. go-plus.json http://purl.obolibrary.org/obo/GO_0010488 GO:0034455 biolink:CellularComponent t-UTP complex A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p. go-plus.json Nan1p-containing subcomplex of 90S preribosome http://purl.obolibrary.org/obo/GO_0034455 CHEBI:62803 biolink:ChemicalSubstance fuel additive go-plus.json http://purl.obolibrary.org/obo/CHEBI_62803 GO:0010489 biolink:MolecularActivity UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose. go-plus.json http://purl.obolibrary.org/obo/GO_0010489 GO:0034456 biolink:CellularComponent UTP-C complex A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p. go-plus.json Rrp7p-containing subcomplex of 90S preribosome http://purl.obolibrary.org/obo/GO_0034456 GO:0034457 biolink:CellularComponent Mpp10 complex A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p. go-plus.json http://purl.obolibrary.org/obo/GO_0034457 GO:0010486 biolink:MolecularActivity manganese:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in). go-plus.json manganese:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0010486 GO:0034458 biolink:MolecularActivity 3'-5' RNA helicase activity Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis. go-plus.json 3' to 5' RNA helicase activity|ATP-dependent 3' to 5' RNA helicase activity|ATP-dependent 3'-5' RNA helicase activity http://purl.obolibrary.org/obo/GO_0034458 GO:0010487 biolink:MolecularActivity thermospermine synthase activity Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+. RHEA:30515|MetaCyc:RXN-11190|EC:2.5.1.79 go-plus.json http://purl.obolibrary.org/obo/GO_0010487 CHEBI:62804 biolink:ChemicalSubstance metallochlorin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62804 CHEBI:62805 biolink:ChemicalSubstance isooctane go-plus.json http://purl.obolibrary.org/obo/CHEBI_62805 chebi_ph7_3 GO:0010480 biolink:BiologicalProcess microsporocyte differentiation The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell. go-plus.json pollen mother cell differentiation http://purl.obolibrary.org/obo/GO_0010480 GO:0010481 biolink:BiologicalProcess epidermal cell division Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. go-plus.json hypodermal cell division http://purl.obolibrary.org/obo/GO_0010481 GO:0034450 biolink:MolecularActivity ubiquitin-ubiquitin ligase activity Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. Reactome:R-HSA-937050|Reactome:R-HSA-975122 go-plus.json E4 http://purl.obolibrary.org/obo/GO_0034450 GO:0034448 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034448 GO:0034449 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034449 GO:0010495 biolink:BiologicalProcess long-distance posttranscriptional gene silencing A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place. go-plus.json long-distance propagation of posttranscriptional gene silencing http://purl.obolibrary.org/obo/GO_0010495 GO:0034440 biolink:BiologicalProcess lipid oxidation The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0034440 GO:0010496 biolink:BiologicalProcess intercellular transport The movement of substances between cells. go-plus.json single organism intercellular transport|single-organism intercellular transport http://purl.obolibrary.org/obo/GO_0010496 GO:0034441 biolink:BiologicalProcess plasma lipoprotein particle oxidation The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids. go-plus.json plasma lipoprotein oxidation http://purl.obolibrary.org/obo/GO_0034441 GO:0010493 biolink:BiologicalProcess Lewis a epitope biosynthetic process The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides. go-plus.json LE A biosynthetic process http://purl.obolibrary.org/obo/GO_0010493 GO:0034442 biolink:BiologicalProcess regulation of lipoprotein oxidation Any process that modulates the frequency, rate or extent of lipoprotein oxidation. go-plus.json http://purl.obolibrary.org/obo/GO_0034442 GO:0034443 biolink:BiologicalProcess negative regulation of lipoprotein oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation. go-plus.json inhibition of lipoprotein oxidation http://purl.obolibrary.org/obo/GO_0034443 GO:0010494 biolink:CellularComponent cytoplasmic stress granule A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Wikipedia:Stress_granule go-plus.json cytoplasmic mRNP granule|stress granule http://purl.obolibrary.org/obo/GO_0010494 GO:0034444 biolink:BiologicalProcess regulation of plasma lipoprotein oxidation Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma. go-plus.json regulation of plasma lipoprotein particle oxidation http://purl.obolibrary.org/obo/GO_0034444 GO:0010499 biolink:BiologicalProcess proteasomal ubiquitin-independent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin. go-plus.json http://purl.obolibrary.org/obo/GO_0010499 GO:0034445 biolink:BiologicalProcess negative regulation of plasma lipoprotein oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma. go-plus.json inhibition of plasma lipoprotein oxidation|negative regulation of plasma lipoprotein particle oxidation http://purl.obolibrary.org/obo/GO_0034445 CHEBI:62814 biolink:ChemicalSubstance heme d cis-diol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62814 chebi_ph7_3 GO:0034446 biolink:BiologicalProcess substrate adhesion-dependent cell spreading The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate. go-plus.json cell spreading during cell substrate adhesion|substrate adhesion dependent cell spreading http://purl.obolibrary.org/obo/GO_0034446 GO:0010497 biolink:BiologicalProcess plasmodesmata-mediated intercellular transport The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. go-plus.json plasmodesmata-mediated cell-to-cell transport|plasmodesma-mediated intercellular transport|plasmodesma-mediated cell-to-cell transport|single-organism plasmodesmata-mediated intercellular transport|single organism plasmodesmata-mediated intercellular transport http://purl.obolibrary.org/obo/GO_0010497 CHEBI:62811 biolink:ChemicalSubstance heme d cis-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62811 GO:0034447 biolink:BiologicalProcess very-low-density lipoprotein particle clearance The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json VLDL clearance http://purl.obolibrary.org/obo/GO_0034447 GO:0010498 biolink:BiologicalProcess proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. go-plus.json proteasome-mediated protein catabolism|proteasome-mediated protein catabolic process http://purl.obolibrary.org/obo/GO_0010498 GO:0010491 biolink:MolecularActivity UTP:arabinose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010491 GO:0010492 biolink:BiologicalProcess maintenance of shoot apical meristem identity The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010492 GO:0010490 biolink:MolecularActivity UDP-4-keto-rhamnose-4-keto-reductase activity Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+. go-plus.json http://purl.obolibrary.org/obo/GO_0010490 GO:0034437 biolink:MolecularActivity obsolete glycoprotein transmembrane transporter activity OBSOLETE. Enables the transfer of a glycoprotein from one side of a membrane to the other. go-plus.json glycoprotein transporter activity http://purl.obolibrary.org/obo/GO_0034437 GO:0034438 biolink:BiologicalProcess lipoprotein amino acid oxidation The modification of a lipoprotein by oxidation of one or more amino acids in the protein. go-plus.json http://purl.obolibrary.org/obo/GO_0034438 GO:0034439 biolink:BiologicalProcess lipoprotein lipid oxidation The modification of a lipoprotein by oxidation of the lipid group. go-plus.json http://purl.obolibrary.org/obo/GO_0034439 GO:0010468 biolink:BiologicalProcess regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. Wikipedia:Regulation_of_gene_expression go-plus.json regulation of protein expression|regulation of gene product expression http://purl.obolibrary.org/obo/GO_0010468 GO:0010469 biolink:BiologicalProcess regulation of signaling receptor activity Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. go-plus.json regulation of signalling receptor activity|regulation of receptor activity http://purl.obolibrary.org/obo/GO_0010469 GO:0009480 biolink:MolecularActivity obsolete class IIb cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json class IIb cytochrome c http://purl.obolibrary.org/obo/GO_0009480 GO:0009481 biolink:MolecularActivity obsolete aa3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. go-plus.json aa3-type cytochrome c oxidase http://purl.obolibrary.org/obo/GO_0009481 GO:0009482 biolink:MolecularActivity obsolete ba3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. go-plus.json ba3-type cytochrome c oxidase http://purl.obolibrary.org/obo/GO_0009482 GO:0009483 biolink:MolecularActivity obsolete caa3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. go-plus.json caa3-type cytochrome c oxidase http://purl.obolibrary.org/obo/GO_0009483 GO:0010462 biolink:BiologicalProcess regulation of light-activated voltage-gated calcium channel activity Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_0010462 GO:0009473 biolink:MolecularActivity obsolete cytochrome c7 (triheme) OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytochrome c7 (triheme) http://purl.obolibrary.org/obo/GO_0009473 GO:0010463 biolink:BiologicalProcess mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json http://purl.obolibrary.org/obo/GO_0010463 GO:0034430 biolink:CellularComponent monolayer-surrounded lipid storage body outer lipid monolayer The single layer of phopholipids surrounding a lipid storage body. go-plus.json oleosome outer lipid monolayer|lipid droplet outer lipid monolayer|oil body outer lipid monolayer|lipid storage body surface lipid monolayer|spherosome outer lipid monolayer http://purl.obolibrary.org/obo/GO_0034430 GO:0009474 biolink:MolecularActivity obsolete nonaheme cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json nonaheme cytochrome c http://purl.obolibrary.org/obo/GO_0009474 GO:0034431 biolink:MolecularActivity bis(5'-adenosyl)-hexaphosphatase activity Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate. RHEA:32047 go-plus.json AP6A hydrolase activity|diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity|AP-6-A hydrolase activity|AP(6)A hydrolase activity http://purl.obolibrary.org/obo/GO_0034431 GO:0009475 biolink:MolecularActivity obsolete high-molecular-weight cytochrome c (hexadecaheme) OBSOLETE. (Was not defined before being made obsolete). go-plus.json high-molecular-weight cytochrome c (hexadecaheme) http://purl.obolibrary.org/obo/GO_0009475 GO:0010460 biolink:BiologicalProcess positive regulation of heart rate Any process that activates or increases the frequency or rate of heart contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0010460 GO:0034432 biolink:MolecularActivity bis(5'-adenosyl)-pentaphosphatase activity Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate. go-plus.json AP5A hydrolase activity|diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity|AP-5-A hydrolase activity|Ap5a pyrophosphohydrolase activity|AP(5)A hydrolase activity http://purl.obolibrary.org/obo/GO_0034432 GO:0009476 biolink:MolecularActivity obsolete class IV cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json class IV cytochrome c http://purl.obolibrary.org/obo/GO_0009476 GO:0010461 biolink:MolecularActivity light-activated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010461 GO:0009477 biolink:MolecularActivity obsolete cytochrome c1 OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c. go-plus.json cytochrome c1 http://purl.obolibrary.org/obo/GO_0009477 GO:0010466 biolink:BiologicalProcess negative regulation of peptidase activity Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010466 GO:0034433 biolink:BiologicalProcess steroid esterification A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol). go-plus.json http://purl.obolibrary.org/obo/GO_0034433 GO:0010467 biolink:BiologicalProcess gene expression The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. Wikipedia:Gene_expression go-plus.json http://purl.obolibrary.org/obo/GO_0010467 goslim_flybase_ribbon GO:0034434 biolink:BiologicalProcess sterol esterification A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol). go-plus.json http://purl.obolibrary.org/obo/GO_0034434 GO:0009478 biolink:MolecularActivity obsolete cytochrome c554 OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytochrome c554 http://purl.obolibrary.org/obo/GO_0009478 GO:0010464 biolink:BiologicalProcess regulation of mesenchymal cell proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json http://purl.obolibrary.org/obo/GO_0010464 GO:0009479 biolink:MolecularActivity obsolete cytochrome f OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin. go-plus.json cytochrome f http://purl.obolibrary.org/obo/GO_0009479 GO:0034435 biolink:BiologicalProcess cholesterol esterification A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0034435 GO:0034436 biolink:BiologicalProcess glycoprotein transport The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0034436 GO:0010465 biolink:MolecularActivity nerve growth factor receptor activity Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity. go-plus.json beta-nerve growth factor receptor activity|NGF receptor activity http://purl.obolibrary.org/obo/GO_0010465 GO:0034426 biolink:CellularComponent etioplast membrane Either of the lipid bilayers that surround a etioplast and form the etioplast envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0034426 GO:0034427 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. go-plus.json 3'-5' exonucleolytic nuclear-transcribed mRNA catabolic process http://purl.obolibrary.org/obo/GO_0034427 GO:0034428 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. go-plus.json 5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process http://purl.obolibrary.org/obo/GO_0034428 GO:0010479 biolink:BiologicalProcess stele development The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds. go-plus.json http://purl.obolibrary.org/obo/GO_0010479 GO:0009490 biolink:MolecularActivity obsolete mononuclear iron electron carrier OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system. go-plus.json mononuclear iron electron carrier http://purl.obolibrary.org/obo/GO_0009490 GO:0034429 biolink:BiologicalProcess tectobulbar tract morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0034429 GO:0009491 biolink:MolecularActivity obsolete redox-active disulfide bond electron carrier OBSOLETE. (Was not defined before being made obsolete). go-plus.json redox-active disulphide bond electron carrier|redox-active disulfide bond electron carrier http://purl.obolibrary.org/obo/GO_0009491 GO:0009492 biolink:MolecularActivity obsolete 2Fe-2S electron transfer carrier OBSOLETE. (Was not defined before being made obsolete). go-plus.json 2Fe-2S electron transfer carrier http://purl.obolibrary.org/obo/GO_0009492 GO:0009493 biolink:MolecularActivity obsolete adrenodoxin-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json adrenodoxin-type ferredoxin http://purl.obolibrary.org/obo/GO_0009493 GO:0009494 biolink:MolecularActivity obsolete chloroplast-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json chloroplast-type ferredoxin http://purl.obolibrary.org/obo/GO_0009494 GO:0010473 biolink:MolecularActivity GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0010473 GO:0009484 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009484 GO:0010474 biolink:MolecularActivity glucose-1-phosphate guanylyltransferase (GDP) activity Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose. go-plus.json GDP:glucose-1-phosphate guanyltransferase activity http://purl.obolibrary.org/obo/GO_0010474 GO:0009485 biolink:MolecularActivity obsolete cbb3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. go-plus.json cbb3-type cytochrome c oxidase http://purl.obolibrary.org/obo/GO_0009485 GO:0034420 biolink:BiologicalProcess co-translational protein acetylation The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome. go-plus.json co-translational protein amino acid acetylation|cotranslational protein amino acid acetylation http://purl.obolibrary.org/obo/GO_0034420 GO:0009486 biolink:MolecularActivity cytochrome bo3 ubiquinol oxidase activity Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]. MetaCyc:RXN0-5268|TC:3.D.4.5.1|RHEA:30251|EC:7.1.1.3 go-plus.json cytochrome o ubiquinol oxidase activity|cytochrome bo oxidase|cytochrome bo(3) oxidase http://purl.obolibrary.org/obo/GO_0009486 GO:0010471 biolink:MolecularActivity GDP-galactose:mannose-1-phosphate guanylyltransferase activity Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate. MetaCyc:RXN4FS-12 go-plus.json GDP-L-galactose:mannose-1-phosphate guanylyltransferase activity|GDP-L-galactose phosphorylase activity http://purl.obolibrary.org/obo/GO_0010471 GO:0034421 biolink:BiologicalProcess post-translational protein acetylation The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome. go-plus.json posttranslational protein amino acid acetylation|post-translational protein amino acid acetylation http://purl.obolibrary.org/obo/GO_0034421 GO:0009487 biolink:MolecularActivity obsolete glutaredoxin OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase. go-plus.json glutaredoxin http://purl.obolibrary.org/obo/GO_0009487 CHEBI:62830 biolink:ChemicalSubstance dTDP-4-dehydro-beta-L-rhamnose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62830 chebi_ph7_3 GO:0010472 biolink:MolecularActivity GDP-galactose:glucose-1-phosphate guanylyltransferase activity Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose. MetaCyc:RXN4FS-13 go-plus.json GDP-L-galactose:glucose-1-phosphate guanylyltransferase activity|GDP-L-galactose phosphorylase activity http://purl.obolibrary.org/obo/GO_0010472 GO:0009488 biolink:MolecularActivity obsolete amicyanin OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c. go-plus.json amicyanin http://purl.obolibrary.org/obo/GO_0009488 GO:0010477 biolink:BiologicalProcess response to sulfur dioxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010477 GO:0034422 biolink:CellularComponent aleurone grain lumen The volume enclosed by the membrane of an aleurone grain. go-plus.json http://purl.obolibrary.org/obo/GO_0034422 GO:0009489 biolink:MolecularActivity obsolete rubredoxin OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues. go-plus.json rubredoxin http://purl.obolibrary.org/obo/GO_0009489 GO:0010478 biolink:BiologicalProcess chlororespiration A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool. go-plus.json http://purl.obolibrary.org/obo/GO_0010478 CHEBI:62836 biolink:ChemicalSubstance 2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_62836 chebi_ph7_3 GO:0034423 biolink:CellularComponent autophagosome lumen The volume enclosed within the autophagosome double-membrane. go-plus.json autophagic vacuole lumen http://purl.obolibrary.org/obo/GO_0034423 GO:0034424 biolink:CellularComponent Vps55/Vps68 complex A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0034424 GO:0010475 biolink:MolecularActivity galactose-1-phosphate guanylyltransferase (GDP) activity Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose. go-plus.json GDP:galactose-1-phosphate guanyltransferase activity http://purl.obolibrary.org/obo/GO_0010475 CHEBI:62833 biolink:ChemicalSubstance 1-myristoyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62833 GO:0010476 biolink:BiologicalProcess gibberellin mediated signaling pathway The series of molecular signals generated as a consequence of gibberellin stimulus. go-plus.json gibberellin-mediated signalling http://purl.obolibrary.org/obo/GO_0010476 GO:0034425 biolink:CellularComponent etioplast envelope The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0034425 CHEBI:62834 biolink:ChemicalSubstance 1-linoleoyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62834 CHEBI:62837 biolink:ChemicalSubstance 1-oleoyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62837 GO:0010470 biolink:BiologicalProcess regulation of gastrulation Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. go-plus.json http://purl.obolibrary.org/obo/GO_0010470 GO:0034415 biolink:BiologicalProcess tRNA 3'-trailer cleavage, exonucleolytic Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA. go-plus.json tRNA 3'-end cleavage, exonucleolytic|exonucleolytic tRNA 3'-trailer cleavage|exonucleolytic tRNA 3'-end cleavage http://purl.obolibrary.org/obo/GO_0034415 GO:0010448 biolink:BiologicalProcess vegetative meristem growth The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia. go-plus.json http://purl.obolibrary.org/obo/GO_0010448 GO:0034416 biolink:MolecularActivity bisphosphoglycerate phosphatase activity Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate. go-plus.json diphosphoglycerate phosphatase activity|2,3-diphosphoglyceric acid phosphatase activity|glycerate-2,3-diphosphate phosphatase activity|2,3-bisphosphoglycerate phosphatase activity|2,3-diphosphoglycerate phosphatase activity http://purl.obolibrary.org/obo/GO_0034416 GO:0010449 biolink:BiologicalProcess root meristem growth The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root. go-plus.json http://purl.obolibrary.org/obo/GO_0010449 GO:0034417 biolink:MolecularActivity bisphosphoglycerate 3-phosphatase activity Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate. KEGG_REACTION:R09532|RHEA:27381|MetaCyc:RXN-11102|EC:3.1.3.80 go-plus.json 2,3-bisphospho-D-glycerate 3-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0034417 GO:0010446 biolink:BiologicalProcess response to alkaline pH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json response to basic pH|response to alkalinity http://purl.obolibrary.org/obo/GO_0010446 GO:0034418 biolink:BiologicalProcess urate biosynthetic process The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine. go-plus.json urate formation|uric acid biosynthetic process|urate biosynthesis|urate synthesis|urate anabolism http://purl.obolibrary.org/obo/GO_0034418 GO:0010447 biolink:BiologicalProcess response to acidic pH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json response to acidity http://purl.obolibrary.org/obo/GO_0010447 GO:0034419 biolink:MolecularActivity obsolete L-2-hydroxyglutarate oxidase activity OBSOLETE. Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide. go-plus.json http://purl.obolibrary.org/obo/GO_0034419 GO:0009460 biolink:MolecularActivity obsolete cytochrome b OBSOLETE. A cytochrome containing noncovalently bound protoheme (iron protoporphyrin IX; heme b). go-plus.json cytochrome b http://purl.obolibrary.org/obo/GO_0009460 GO:0009461 biolink:MolecularActivity obsolete cytochrome c OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues. go-plus.json http://purl.obolibrary.org/obo/GO_0009461 GO:0010440 biolink:BiologicalProcess stomatal lineage progression The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex. go-plus.json http://purl.obolibrary.org/obo/GO_0010440 GO:0009451 biolink:BiologicalProcess RNA modification The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. Wikipedia:RNA_editing go-plus.json RNA editing http://purl.obolibrary.org/obo/GO_0009451 goslim_yeast GO:0010441 biolink:BiologicalProcess guard cell development The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0010441 GO:0009452 biolink:BiologicalProcess 7-methylguanosine RNA capping The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. go-plus.json m(7)G RNA capping|RNA capping http://purl.obolibrary.org/obo/GO_0009452 GO:0009453 biolink:BiologicalProcess energy taxis The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. go-plus.json energytaxis|taxis in response to energy source http://purl.obolibrary.org/obo/GO_0009453 CHEBI:62840 biolink:ChemicalSubstance 1-lauroyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62840 GO:0009454 biolink:BiologicalProcess aerotaxis The directed movement of a motile cell or organism in response to environmental oxygen. go-plus.json taxis in response to atmospheric oxygen http://purl.obolibrary.org/obo/GO_0009454 GO:0034410 biolink:BiologicalProcess cell wall beta-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells. go-plus.json cell wall beta-glucan anabolism|cell wall beta-glucan synthesis|cell wall beta-glucan formation|cell wall beta-glucan biosynthesis http://purl.obolibrary.org/obo/GO_0034410 GO:0034411 biolink:BiologicalProcess cell wall (1->3)-beta-D-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. go-plus.json cell wall 1,3-beta-glucan synthesis|cell wall 1,3-beta-glucan formation|cell wall 1,3-beta-glucan biosynthesis|cell wall beta-1,3-glucan biosynthesis|cell wall beta-1,3-glucan anabolism|cell wall beta-1,3-glucan biosynthetic process|cell wall 1,3-beta-glucan biosynthetic process|cell wall beta-1,3-glucan synthesis|cell wall beta-1,3-glucan formation|cell wall 1,3-beta-D-glucan biosynthetic process|cell wall 1,3-beta-glucan anabolism http://purl.obolibrary.org/obo/GO_0034411 GO:0009455 biolink:BiologicalProcess redox taxis The directed movement of a motile cell or organism in response to redox potential. go-plus.json taxis in response to redox stimulus|taxis in response to redox potential|redoxtaxis http://purl.obolibrary.org/obo/GO_0009455 GO:0010444 biolink:BiologicalProcess guard mother cell differentiation The process in which a meristemoid acquires the specialized features of a guard mother cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010444 CHEBI:62846 biolink:ChemicalSubstance 4-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62846 GO:0010445 biolink:CellularComponent nuclear dicing body A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes. go-plus.json D body http://purl.obolibrary.org/obo/GO_0010445 GO:0034412 biolink:BiologicalProcess ascospore wall beta-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. go-plus.json ascospore wall beta-glucan anabolism|ascospore wall beta-glucan synthesis|ascospore wall beta-glucan formation|ascospore wall beta-glucan biosynthesis http://purl.obolibrary.org/obo/GO_0034412 CHEBI:62847 biolink:ChemicalSubstance 6alpha-hydroxy-17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62847 chebi_ph7_3 GO:0009456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009456 GO:0034413 biolink:BiologicalProcess ascospore wall (1->3)-beta-D-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. go-plus.json ascospore wall 1,3-beta-glucan anabolism|ascospore wall 1,3-beta-glucan biosynthesis|ascospore wall 1,3-beta-glucan synthesis|ascospore wall 1,3-beta-glucan formation|ascospore wall beta-1,3-glucan biosynthesis|ascospore wall beta-1,3-glucan biosynthetic process|ascospore wall 1,3-beta-glucan biosynthetic process|ascospore wall beta-1,3-glucan anabolism|ascospore wall 1,3-beta-D-glucan biosynthetic process|ascospore wall beta-1,3-glucan synthesis|ascospore wall beta-1,3-glucan formation http://purl.obolibrary.org/obo/GO_0034413 GO:0010442 biolink:BiologicalProcess guard cell morphogenesis Generation and organization of the polarized cell that is capable of turgor driven movement. go-plus.json guard cell morphogenesis during differentiation http://purl.obolibrary.org/obo/GO_0010442 GO:0009457 biolink:MolecularActivity obsolete flavodoxin OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide. go-plus.json flavodoxin http://purl.obolibrary.org/obo/GO_0009457 GO:0034414 biolink:BiologicalProcess tRNA 3'-trailer cleavage, endonucleolytic Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA. go-plus.json tRNA 3'-end cleavage, endonucleolytic|endonucleolytic tRNA 3'-trailer cleavage|endonucleolytic tRNA 3'-end cleavage http://purl.obolibrary.org/obo/GO_0034414 GO:0009458 biolink:MolecularActivity obsolete cytochrome OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom. go-plus.json cytochrome http://purl.obolibrary.org/obo/GO_0009458 GO:0010443 biolink:BiologicalProcess meristemoid mother cell division The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC. go-plus.json meristemoid division http://purl.obolibrary.org/obo/GO_0010443 CHEBI:62845 biolink:ChemicalSubstance 4-hydroxy-17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62845 chebi_ph7_3 CHEBI:47291 biolink:ChemicalSubstance 3-chloro-D-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_47291 chebi_ph7_3 GO:0009459 biolink:MolecularActivity obsolete cytochrome a OBSOLETE. A cytochrome containing heme a. go-plus.json cytochrome a http://purl.obolibrary.org/obo/GO_0009459 CHEBI:144940 biolink:ChemicalSubstance L-alanyl-AMP zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_144940 chebi_ph7_3 GO:0034404 biolink:BiologicalProcess nucleobase-containing small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. go-plus.json nucleobase, nucleoside and nucleotide biosynthesis|nucleobase, nucleoside and nucleotide anabolism|nucleobase, nucleoside and nucleotide synthesis|nucleobase, nucleoside and nucleotide formation http://purl.obolibrary.org/obo/GO_0034404 GO:0010459 biolink:BiologicalProcess negative regulation of heart rate Any process that stops, prevents or reduces the frequency or rate of heart contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0010459 GO:0034405 biolink:BiologicalProcess response to fluid shear stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. go-plus.json http://purl.obolibrary.org/obo/GO_0034405 GO:0010457 biolink:BiologicalProcess centriole-centriole cohesion The cell cycle process in which the two centrioles within a centrosome remain tightly paired. go-plus.json http://purl.obolibrary.org/obo/GO_0010457 GO:0034406 biolink:BiologicalProcess cell wall beta-glucan metabolic process The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells. go-plus.json cell wall beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0034406 GO:0034407 biolink:BiologicalProcess cell wall (1->3)-beta-D-glucan metabolic process The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. go-plus.json cell wall 1,3-beta-glucan metabolism|cell wall beta-1,3 glucan metabolic process|cell wall 1,3-beta-glucan metabolic process|cell wall 1,3-beta-D-glucan metabolic process|cell wall beta-1,3 glucan metabolism http://purl.obolibrary.org/obo/GO_0034407 CHEBI:1617 biolink:ChemicalSubstance 4-hydroxy-3-octaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_1617 chebi_ph7_3 GO:0010458 biolink:BiologicalProcess exit from mitosis The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. go-plus.json exit from mitotic division|mitotic exit http://purl.obolibrary.org/obo/GO_0010458 GO:0034408 biolink:BiologicalProcess ascospore wall beta-glucan metabolic process The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. go-plus.json ascospore wall beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0034408 GO:0009470 biolink:MolecularActivity obsolete class IIa cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json class IIa cytochrome c http://purl.obolibrary.org/obo/GO_0009470 GO:0034409 biolink:BiologicalProcess ascospore wall (1->3)-beta-D-glucan metabolic process The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. go-plus.json ascospore wall 1,3-beta-D-glucan metabolic process|ascospore wall beta-1,3 glucan metabolic process|ascospore wall 1,3-beta-glucan metabolic process|ascospore wall beta-1,3 glucan metabolism|ascospore wall 1,3-beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0034409 GO:0009471 biolink:MolecularActivity obsolete class III cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json class III cytochrome c http://purl.obolibrary.org/obo/GO_0009471 GO:0009472 biolink:MolecularActivity obsolete cytochrome c3 (tetraheme) OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytochrome c3 (tetraheme) http://purl.obolibrary.org/obo/GO_0009472 GO:0009462 biolink:MolecularActivity obsolete cytochrome d OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes. go-plus.json cytochrome d http://purl.obolibrary.org/obo/GO_0009462 GO:0010451 biolink:BiologicalProcess floral meristem growth The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower. go-plus.json http://purl.obolibrary.org/obo/GO_0010451 GO:0009463 biolink:MolecularActivity obsolete cytochrome b/b6 OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis. go-plus.json cytochrome b/b6 http://purl.obolibrary.org/obo/GO_0009463 GO:0010452 biolink:BiologicalProcess histone H3-K36 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone. go-plus.json histone lysine H3 K36 methylation|histone H3 K36 methylation|histone H3K36me http://purl.obolibrary.org/obo/GO_0010452 GO:0009464 biolink:MolecularActivity obsolete cytochrome b5 OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytochrome b5 http://purl.obolibrary.org/obo/GO_0009464 GO:0009465 biolink:MolecularActivity obsolete soluble cytochrome b562 OBSOLETE. (Was not defined before being made obsolete). go-plus.json soluble cytochrome b562 http://purl.obolibrary.org/obo/GO_0009465 GO:0010450 biolink:BiologicalProcess inflorescence meristem growth The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers. go-plus.json http://purl.obolibrary.org/obo/GO_0010450 GO:0034400 biolink:CellularComponent gerontoplast A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence. go-plus.json http://purl.obolibrary.org/obo/GO_0034400 GO:0010455 biolink:BiologicalProcess positive regulation of cell fate commitment Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. go-plus.json http://purl.obolibrary.org/obo/GO_0010455 GO:0009466 biolink:MolecularActivity obsolete class I cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json class I cytochrome c http://purl.obolibrary.org/obo/GO_0009466 CHEBI:62857 biolink:ChemicalSubstance alpha-L-Fucp-(1->2)-D-Galp go-plus.json http://purl.obolibrary.org/obo/CHEBI_62857 chebi_ph7_3 GO:0034401 biolink:BiologicalProcess obsolete chromatin organization involved in regulation of transcription OBSOLETE. Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription. go-plus.json stimulation of global transcription from RNA polymerase II promoter by histone modification|regulation of transcription from RNA polymerase II promoter, global by histone modification|activation of global transcription from RNA polymerase II promoter by histone modification|activation of transcription from RNA polymerase II promoter by histone modification|positive regulation of global transcription from Pol II promoter by histone modification|stimulation of transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter, global by histone modification|regulation of transcription from RNA polymerase II promoter by histone modification|up-regulation of transcription from RNA polymerase II promoter by histone modification|up regulation of global transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from Pol II promoter by histone modification|regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter by histone modification|upregulation of transcription from RNA polymerase II promoter by histone modification|upregulation of global transcription from RNA polymerase II promoter by histone modification|positive regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|regulation of transcription from Pol II promoter by histone modification|regulation of transcription by chromatin organisation|up regulation of transcription from RNA polymerase II promoter by histone modification|up-regulation of global transcription from RNA polymerase II promoter by histone modification|establishment or maintenance of chromatin architecture during transcription|regulation of global transcription from Pol II promoter by histone modification|regulation of transcription by chromatin organization http://purl.obolibrary.org/obo/GO_0034401 GO:0009467 biolink:MolecularActivity obsolete monoheme class I cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json monoheme class I cytochrome c http://purl.obolibrary.org/obo/GO_0009467 GO:0010456 biolink:BiologicalProcess cell proliferation in dorsal spinal cord The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0010456 CHEBI:62858 biolink:ChemicalSubstance 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62858 GO:0010453 biolink:BiologicalProcess regulation of cell fate commitment Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. go-plus.json http://purl.obolibrary.org/obo/GO_0010453 GO:0009468 biolink:MolecularActivity obsolete diheme class I cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json diheme class I cytochrome c http://purl.obolibrary.org/obo/GO_0009468 GO:0034402 biolink:BiologicalProcess recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0034402 GO:0010454 biolink:BiologicalProcess negative regulation of cell fate commitment Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. go-plus.json http://purl.obolibrary.org/obo/GO_0010454 GO:0009469 biolink:MolecularActivity obsolete class II cytochrome c OBSOLETE. (Was not defined before being made obsolete). go-plus.json class II cytochrome c http://purl.obolibrary.org/obo/GO_0009469 GO:0034403 biolink:BiologicalProcess alignment of 3' and 5' splice sites of mRNA Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur. go-plus.json alignment of 3' and 5' splice sites of nuclear mRNA http://purl.obolibrary.org/obo/GO_0034403 GO:0010426 biolink:BiologicalProcess DNA methylation on cytosine within a CHH sequence The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide. go-plus.json cytosine methylation within a CNN sequence|cytosine methylation within a CHH sequence|DNA methylation on cytosine within a CNN sequence http://purl.obolibrary.org/obo/GO_0010426 GO:0010427 biolink:MolecularActivity abscisic acid binding Binding to abscisic acid, a plant hormone that regulates aspects of plant growth. go-plus.json abscisate binding|ABA binding http://purl.obolibrary.org/obo/GO_0010427 GO:0010424 biolink:BiologicalProcess DNA methylation on cytosine within a CG sequence The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule. go-plus.json cytosine methylation within a CG sequence http://purl.obolibrary.org/obo/GO_0010424 GO:0010425 biolink:BiologicalProcess DNA methylation on cytosine within a CNG sequence The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide. go-plus.json cytosine methylation within a CNG sequence http://purl.obolibrary.org/obo/GO_0010425 CHEBI:62860 biolink:ChemicalSubstance 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62860 chebi_ph7_3 GO:0010428 biolink:MolecularActivity methyl-CpNpG binding Binding to a methylated cytosine/unspecified/guanine trinucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0010428 GO:0010429 biolink:MolecularActivity methyl-CpNpN binding Binding to a methylated cytosine/unspecified/unspecified trinucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0010429 CHEBI:47266 biolink:ChemicalSubstance hydrogen bromide go-plus.json http://purl.obolibrary.org/obo/CHEBI_47266 GO:0009430 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009430 GO:0009431 biolink:CellularComponent bacterial-type flagellum basal body, MS ring One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane. go-plus.json flagellin-based flagellum basal body, MS ring|flagellar basal body, mounting plate|flagellar basal body, MS ring http://purl.obolibrary.org/obo/GO_0009431 GO:0009432 biolink:BiologicalProcess SOS response An error-prone process for repairing damaged microbial DNA. Wikipedia:SOS_response go-plus.json http://purl.obolibrary.org/obo/GO_0009432 GO:0009433 biolink:CellularComponent bacterial-type flagellum basal body, C ring Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise. go-plus.json flagellar basal body, C ring|flagellin-based flagellum basal body, C ring http://purl.obolibrary.org/obo/GO_0009433 GO:0010422 biolink:BiologicalProcess regulation of brassinosteroid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids. go-plus.json http://purl.obolibrary.org/obo/GO_0010422 CHEBI:62868 biolink:ChemicalSubstance hepatoprotective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_62868 GO:0010423 biolink:BiologicalProcess negative regulation of brassinosteroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids. go-plus.json http://purl.obolibrary.org/obo/GO_0010423 GO:0009434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009434 GO:0009435 biolink:BiologicalProcess NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json reduced NAD biosynthesis|reduced NAD biosynthetic process|NAD biosynthesis|reduced nicotinamide adenine dinucleotide biosynthesis|reduced nicotinamide adenine dinucleotide biosynthetic process|nicotinamide adenine dinucleotide biosynthetic process|nicotinamide adenine dinucleotide biosynthesis|NADH biosynthetic process|NADH biosynthesis|NAD (oxidized) biosynthetic process|NAD (oxidized) biosynthesis|NAD anabolism|NAD (reduced) biosynthesis|NAD (reduced) biosynthetic process|oxidized NAD biosynthetic process|oxidized NAD biosynthesis|NAD synthesis|oxidized nicotinamide adenine dinucleotide biosynthesis|oxidized nicotinamide adenine dinucleotide biosynthetic process|NAD formation http://purl.obolibrary.org/obo/GO_0009435 CHEBI:62866 biolink:ChemicalSubstance 2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_62866 chebi_ph7_3 GO:0010420 biolink:MolecularActivity 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-9281|RHEA:44452|EC:2.1.1.114 go-plus.json polyprenyldihydroxybenzoate methyltransferase activity http://purl.obolibrary.org/obo/GO_0010420 GO:0010421 biolink:BiologicalProcess hydrogen peroxide-mediated programmed cell death Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes. go-plus.json programmed cell death in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_0010421 GO:0009436 biolink:BiologicalProcess glyoxylate catabolic process The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH. MetaCyc:GLYOXDEG-PWY go-plus.json glyoxylate catabolism|glyoxylate degradation|glyoxylate breakdown http://purl.obolibrary.org/obo/GO_0009436 CHEBI:62867 biolink:ChemicalSubstance soyasaponin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_62867 GO:0009437 biolink:BiologicalProcess carnitine metabolic process The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. go-plus.json carnitine metabolism|vitamin Bt metabolism|vitamin Bt metabolic process http://purl.obolibrary.org/obo/GO_0009437 GO:0009438 biolink:BiologicalProcess methylglyoxal metabolic process The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. MetaCyc:METHGLYUT-PWY go-plus.json methylglyoxal pathway|methylglyoxal bypass|methylglyoxal metabolism http://purl.obolibrary.org/obo/GO_0009438 GO:0009439 biolink:BiologicalProcess cyanate metabolic process The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid. MetaCyc:CYANCAT-PWY go-plus.json cyanate metabolism http://purl.obolibrary.org/obo/GO_0009439 GO:0010437 biolink:MolecularActivity 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond. go-plus.json http://purl.obolibrary.org/obo/GO_0010437 GO:0010438 biolink:BiologicalProcess cellular response to sulfur starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur. go-plus.json http://purl.obolibrary.org/obo/GO_0010438 GO:0010435 biolink:MolecularActivity 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0. EC:6.2.1.-|MetaCyc:RXN-10695 go-plus.json OPC-8:0 CoA ligase activity|3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity http://purl.obolibrary.org/obo/GO_0010435 GO:0010436 biolink:MolecularActivity carotenoid dioxygenase activity Catalysis of the oxidative cleavage of carotenoids. go-plus.json carotenoid-cleaving dioxygenase http://purl.obolibrary.org/obo/GO_0010436 CHEBI:62871 biolink:ChemicalSubstance EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62871 CHEBI:62872 biolink:ChemicalSubstance EC 1.2.3.1 (aldehyde oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_62872 GO:0010439 biolink:BiologicalProcess regulation of glucosinolate biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. go-plus.json http://purl.obolibrary.org/obo/GO_0010439 GO:0009450 biolink:BiologicalProcess gamma-aminobutyric acid catabolic process The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. MetaCyc:4AMINOBUTMETAB-PWY go-plus.json GABA catabolism|GABA catabolic process|4-aminobutyrate catabolism|gamma-aminobutyric acid catabolism|4-aminobutanoate catabolic process|gamma-aminobutyric acid degradation|4-aminobutanoate catabolism|gamma-aminobutyric acid breakdown|4-aminobutyrate catabolic process http://purl.obolibrary.org/obo/GO_0009450 CHEBI:62875 biolink:ChemicalSubstance 2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62875 chebi_ph7_3 GO:0009440 biolink:BiologicalProcess cyanate catabolic process The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid. go-plus.json cyanate catabolism|cyanate degradation|cyanate breakdown http://purl.obolibrary.org/obo/GO_0009440 GO:0010430 biolink:BiologicalProcess fatty acid omega-oxidation A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation. MetaCyc:PWY-2724 go-plus.json http://purl.obolibrary.org/obo/GO_0010430 GO:0009441 biolink:BiologicalProcess glycolate metabolic process The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid). MetaCyc:GLYCOLATEMET-PWY go-plus.json glycolate metabolism http://purl.obolibrary.org/obo/GO_0009441 GO:0009442 biolink:BiologicalProcess allantoin assimilation pathway The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP. MetaCyc:PWY0-41 go-plus.json allantoin catabolism via ureidoglycolate|allantoin degradation pathway|allantoin catabolic process via ureidoglycolate http://purl.obolibrary.org/obo/GO_0009442 CHEBI:62873 biolink:ChemicalSubstance odorant receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_62873 GO:0009443 biolink:BiologicalProcess pyridoxal 5'-phosphate salvage Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis. MetaCyc:PLPSAL-PWY go-plus.json pyridoxal 5' phosphate salvage http://purl.obolibrary.org/obo/GO_0009443 CHEBI:62879 biolink:ChemicalSubstance 2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_62879 chebi_ph7_3 GO:0009444 biolink:BiologicalProcess pyruvate oxidation The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate. MetaCyc:PYRUVOX-PWY|Wikipedia:Pyruvate_decarboxylation go-plus.json http://purl.obolibrary.org/obo/GO_0009444 GO:0010433 biolink:BiologicalProcess bract morphogenesis The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence. go-plus.json http://purl.obolibrary.org/obo/GO_0010433 GO:0009445 biolink:BiologicalProcess putrescine metabolic process The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine. go-plus.json putrescine metabolism http://purl.obolibrary.org/obo/GO_0009445 GO:0010434 biolink:BiologicalProcess bract formation The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence. go-plus.json http://purl.obolibrary.org/obo/GO_0010434 GO:0010431 biolink:BiologicalProcess seed maturation A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination. go-plus.json http://purl.obolibrary.org/obo/GO_0010431 CHEBI:62877 biolink:ChemicalSubstance 2-deoxy-D-ribofuranose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62877 chebi_ph7_3 GO:0009446 biolink:BiologicalProcess putrescine biosynthetic process The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine. go-plus.json putrescine anabolism|putrescine synthesis|putrescine formation|putrescine biosynthesis http://purl.obolibrary.org/obo/GO_0009446 GO:0009447 biolink:BiologicalProcess putrescine catabolic process The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine. go-plus.json putrescine catabolism|putrescine degradation|putrescine breakdown http://purl.obolibrary.org/obo/GO_0009447 GO:0010432 biolink:BiologicalProcess bract development The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence. go-plus.json http://purl.obolibrary.org/obo/GO_0010432 GO:0009448 biolink:BiologicalProcess gamma-aminobutyric acid metabolic process The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. go-plus.json 4-aminobutyrate metabolism|gamma-aminobutyric acid metabolism|4-aminobutyrate metabolic process|4-aminobutanoate metabolism|GABA metabolic process|GABA metabolism|4-aminobutanoate metabolic process http://purl.obolibrary.org/obo/GO_0009448 GO:0009449 biolink:BiologicalProcess gamma-aminobutyric acid biosynthetic process The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. go-plus.json gamma-aminobutyric acid biosynthesis|4-aminobutanoate biosynthesis|4-aminobutanoate biosynthetic process|gamma-aminobutyric acid anabolism|gamma-aminobutyric acid synthesis|GABA biosynthetic process|GABA biosynthesis|gamma-aminobutyric acid formation|4-aminobutyrate biosynthesis|4-aminobutyrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009449 GO:0034396 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to iron Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus. go-plus.json inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of transcription from Pol II promoter in response to iron|down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of transcription from RNA polymerase II promoter in response to iron http://purl.obolibrary.org/obo/GO_0034396 GO:0034397 biolink:BiologicalProcess telomere localization Any process in which a telomere is transported to, and/or maintained in, a specific location. go-plus.json telomere localisation http://purl.obolibrary.org/obo/GO_0034397 GO:0034398 biolink:BiologicalProcess telomere tethering at nuclear periphery The process in which a telomere is maintained in a specific location at the nuclear periphery. go-plus.json http://purl.obolibrary.org/obo/GO_0034398 GO:0034399 biolink:CellularComponent nuclear periphery The portion of the nuclear lumen proximal to the inner nuclear membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034399 CHEBI:1624 biolink:ChemicalSubstance 3-oxo-5beta-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1624 chebi_ph7_3 GO:0034390 biolink:BiologicalProcess smooth muscle cell apoptotic process Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. go-plus.json smooth muscle cell programmed cell death by apoptosis|SMC apoptosis|apoptosis of smooth muscle cells|smooth muscle cell apoptosis|programmed cell death, smooth muscle cells|programmed cell death of smooth muscle cells by apoptosis http://purl.obolibrary.org/obo/GO_0034390 GO:0034391 biolink:BiologicalProcess regulation of smooth muscle cell apoptotic process Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. go-plus.json regulation of smooth muscle cell apoptosis|regulation of SMC apoptosis http://purl.obolibrary.org/obo/GO_0034391 GO:0034392 biolink:BiologicalProcess negative regulation of smooth muscle cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. go-plus.json inhibition of smooth muscle cell apoptosis|negative regulation of SMC apoptosis|negative regulation of smooth muscle cell apoptosis|down-regulation of smooth muscle cell apoptosis|downregulation of smooth muscle cell apoptosis|down regulation of smooth muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0034392 GO:0034393 biolink:BiologicalProcess positive regulation of smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. go-plus.json positive regulation of SMC apoptosis|upregulation of smooth muscle cell apoptosis|stimulation of smooth muscle cell apoptosis|up-regulation of smooth muscle cell apoptosis|activation of smooth muscle cell apoptosis|positive regulation of smooth muscle cell apoptosis|up regulation of smooth muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0034393 GO:0034394 biolink:BiologicalProcess protein localization to cell surface A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane. go-plus.json protein localisation at cell surface|protein localization at cell surface http://purl.obolibrary.org/obo/GO_0034394 GO:0034395 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to iron Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus. go-plus.json regulation of specific transcription from RNA polymerase II promoter in response to iron http://purl.obolibrary.org/obo/GO_0034395 GO:0034385 biolink:CellularComponent triglyceride-rich plasma lipoprotein particle A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood. go-plus.json triacylglycerol-rich lipoprotein particle|triglyceride-rich lipoprotein particle http://purl.obolibrary.org/obo/GO_0034385 GO:0034386 biolink:MolecularActivity 4-aminobutyrate:2-oxoglutarate transaminase activity Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate. MetaCyc:GABATRANSAM-RXN|EC:2.6.1.19 go-plus.json GABA-2-oxoglutarate transaminase activity|GABA-alpha-ketoglutarate transaminase activity|4-aminobutyrate-2-oxoglutarate transaminase activity|gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-2-oxoglutarate transaminase activity|4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity|gamma-aminobutyrate-alpha-ketoglutarate transaminase activity|GABA-oxoglutarate aminotransferase activity|GABA-2-oxoglutarate aminotransferase activity|GABA-alpha-ketoglutaric acid transaminase activity|GABA-alpha-ketoglutarate aminotransferase activity|4-aminobutyrate-2-oxoglutarate aminotransferase activity|4-aminobutanoate:2-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity|gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity|4-aminobutyrate-2-ketoglutarate aminotransferase activity|gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity|GABA-oxoglutarate transaminase activity|GABA-alpha-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0034386 GO:0034387 biolink:MolecularActivity 4-aminobutyrate:pyruvate transaminase activity Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine. EC:2.6.1.96|RHEA:32263|MetaCyc:RXN-6902 go-plus.json gamma-aminobutyric acid pyruvate transaminase activity http://purl.obolibrary.org/obo/GO_0034387 GO:0034388 biolink:CellularComponent Pwp2p-containing subcomplex of 90S preribosome A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p. go-plus.json 25-30 S subcomplex of 90S preribosome|UTP-B complex http://purl.obolibrary.org/obo/GO_0034388 GO:0034389 biolink:BiologicalProcess lipid droplet organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle. go-plus.json lipid particle organisation|lipid particle organization and biogenesis|lipid body organization|lipid particle organization|adiposome organization http://purl.obolibrary.org/obo/GO_0034389 GO:0034380 biolink:BiologicalProcess high-density lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. go-plus.json HDL assembly http://purl.obolibrary.org/obo/GO_0034380 GO:0034381 biolink:BiologicalProcess plasma lipoprotein particle clearance The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json lipoprotein particle clearance http://purl.obolibrary.org/obo/GO_0034381 GO:0034382 biolink:BiologicalProcess chylomicron remnant clearance The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0034382 GO:0034383 biolink:BiologicalProcess low-density lipoprotein particle clearance The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json LDL clearance http://purl.obolibrary.org/obo/GO_0034383 GO:0034384 biolink:BiologicalProcess high-density lipoprotein particle clearance The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json HDL clearance http://purl.obolibrary.org/obo/GO_0034384 GO:0034374 biolink:BiologicalProcess low-density lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. go-plus.json LDL remodeling|small dense LDL formation|small dense low-density lipoprotein particle formation http://purl.obolibrary.org/obo/GO_0034374 GO:0034375 biolink:BiologicalProcess high-density lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. go-plus.json HDL remodeling http://purl.obolibrary.org/obo/GO_0034375 GO:0034376 biolink:BiologicalProcess conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle. go-plus.json discoidal high-density lipoprotein remodeling|discoidal HDL remodeling|conversion of discoidal HDL to spherical HDL http://purl.obolibrary.org/obo/GO_0034376 GO:0034377 biolink:BiologicalProcess plasma lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0034377 GO:0034378 biolink:BiologicalProcess chylomicron assembly The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron. go-plus.json http://purl.obolibrary.org/obo/GO_0034378 GO:0034379 biolink:BiologicalProcess very-low-density lipoprotein particle assembly The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle. go-plus.json VLDL assembly http://purl.obolibrary.org/obo/GO_0034379 GO:0034370 biolink:BiologicalProcess triglyceride-rich lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle. go-plus.json triacylglycerol-rich lipoprotein particle remodeling http://purl.obolibrary.org/obo/GO_0034370 GO:0034371 biolink:BiologicalProcess chylomicron remodeling The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json chylomicron remnant formation http://purl.obolibrary.org/obo/GO_0034371 GO:0034372 biolink:BiologicalProcess very-low-density lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json IDL formation|intermediate-density lipoprotein particle formation|VLDL remodeling http://purl.obolibrary.org/obo/GO_0034372 GO:0034373 biolink:BiologicalProcess intermediate-density lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle. go-plus.json LDL formation|low-density lipoprotein particle formation|IDL remodeling http://purl.obolibrary.org/obo/GO_0034373 GO:0034363 biolink:CellularComponent intermediate-density lipoprotein particle A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL). go-plus.json IDL particle|intermediate-density lipoprotein complex|IDL complex http://purl.obolibrary.org/obo/GO_0034363 GO:0034364 biolink:CellularComponent high-density lipoprotein particle A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process. go-plus.json HDL particle|high-density lipoprotein class complex|HDL complex|HDL3|HDL2 http://purl.obolibrary.org/obo/GO_0034364 GO:0034365 biolink:CellularComponent discoidal high-density lipoprotein particle A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase). go-plus.json nascent HDL|discoidal HDL|nascent high-density lipoprotein particle http://purl.obolibrary.org/obo/GO_0034365 GO:0034366 biolink:CellularComponent spherical high-density lipoprotein particle A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). go-plus.json mature HDL|spherical HDL|mature high-density lipoprotein particle http://purl.obolibrary.org/obo/GO_0034366 GO:0034367 biolink:BiologicalProcess protein-containing complex remodeling The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex. go-plus.json macromolecular complex remodeling http://purl.obolibrary.org/obo/GO_0034367 GO:0034368 biolink:BiologicalProcess protein-lipid complex remodeling The acquisition, loss or modification of a protein or lipid within a protein-lipid complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034368 GO:0034369 biolink:BiologicalProcess plasma lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). go-plus.json http://purl.obolibrary.org/obo/GO_0034369 GO:0034360 biolink:CellularComponent chylomicron remnant A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver. go-plus.json http://purl.obolibrary.org/obo/GO_0034360 GO:0034361 biolink:CellularComponent very-low-density lipoprotein particle A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver. go-plus.json very-low-density lipoprotein complex|VLDL complex|VLDL particle http://purl.obolibrary.org/obo/GO_0034361 GO:0034362 biolink:CellularComponent low-density lipoprotein particle A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. go-plus.json LDL particle|low-density lipoprotein complex|LDL complex http://purl.obolibrary.org/obo/GO_0034362 GO:0009396 biolink:BiologicalProcess folic acid-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid and its derivatives. go-plus.json folic acid and derivative biosynthesis|folic acid-containing compound biosynthesis|folic acid and derivative biosynthetic process|vitamin M and derivative biosynthetic process|vitamin M and derivative biosynthesis|folate-containing compound biosynthesis|folate-containing compound biosynthetic process|folate and derivative biosynthesis|folate and derivative biosynthetic process|folic acid-containing compound anabolism|folic acid-containing compound synthesis|vitamin B9 and derivative biosynthetic process|folic acid-containing compound formation|vitamin B9 and derivative biosynthesis http://purl.obolibrary.org/obo/GO_0009396 GO:0034352 biolink:BiologicalProcess positive regulation of glial cell apoptotic process Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process. go-plus.json positive regulation of glial cell apoptosis|up regulation of glial cell apoptosis|upregulation of glial cell apoptosis|stimulation of glial cell apoptosis|up-regulation of glial cell apoptosis|activation of glial cell apoptosis http://purl.obolibrary.org/obo/GO_0034352 GO:0010385 biolink:MolecularActivity double-stranded methylated DNA binding Binding to double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks. go-plus.json http://purl.obolibrary.org/obo/GO_0010385 GO:0009397 biolink:BiologicalProcess folic acid-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives. go-plus.json vitamin M and derivative catabolism|folate and derivative catabolic process|folate-containing compound catabolic process|folic acid-containing compound degradation|folic acid-containing compound breakdown|folate-containing compound catabolism|vitamin M and derivative catabolic process|folate and derivative catabolism|folic acid and derivative catabolic process|vitamin B9 and derivative catabolic process|vitamin B9 and derivative catabolism|folic acid and derivative catabolism|folic acid-containing compound catabolism http://purl.obolibrary.org/obo/GO_0009397 GO:0010386 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010386 GO:0034353 biolink:MolecularActivity RNA pyrophosphohydrolase activity Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end. go-plus.json http://purl.obolibrary.org/obo/GO_0034353 GO:0009398 biolink:BiologicalProcess FMN biosynthetic process The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase. go-plus.json FMN anabolism|FMN synthesis|FMN formation|FMN biosynthesis http://purl.obolibrary.org/obo/GO_0009398 GO:0034354 biolink:BiologicalProcess 'de novo' NAD biosynthetic process from tryptophan The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json de novo NAD biosynthetic process from tryptophan http://purl.obolibrary.org/obo/GO_0034354 GO:0010383 biolink:BiologicalProcess cell wall polysaccharide metabolic process The chemical reactions and pathways involving cell wall polysaccharides. go-plus.json http://purl.obolibrary.org/obo/GO_0010383 GO:0009399 biolink:BiologicalProcess nitrogen fixation The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide. MetaCyc:N2FIX-PWY|Wikipedia:Nitrogen_fixation go-plus.json http://purl.obolibrary.org/obo/GO_0009399 GO:0034355 biolink:BiologicalProcess NAD salvage Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam). go-plus.json NAD salvage pathway http://purl.obolibrary.org/obo/GO_0034355 GO:0010384 biolink:BiologicalProcess cell wall proteoglycan metabolic process The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates. go-plus.json cell wall proteoglycan metabolism http://purl.obolibrary.org/obo/GO_0010384 GO:0010389 biolink:BiologicalProcess regulation of G2/M transition of mitotic cell cycle Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. go-plus.json regulation of mitotic entry http://purl.obolibrary.org/obo/GO_0010389 GO:0034356 biolink:BiologicalProcess NAD biosynthesis via nicotinamide riboside salvage pathway The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside. go-plus.json nicotinamide riboside salvage pathway|NR salvage pathway http://purl.obolibrary.org/obo/GO_0034356 GO:0034357 biolink:CellularComponent photosynthetic membrane A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place. go-plus.json http://purl.obolibrary.org/obo/GO_0034357 GO:0034358 biolink:CellularComponent plasma lipoprotein particle A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0034358 GO:0010387 biolink:BiologicalProcess COP9 signalosome assembly The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome. go-plus.json signalosome assembly http://purl.obolibrary.org/obo/GO_0010387 GO:0034359 biolink:CellularComponent mature chylomicron A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0034359 GO:0010388 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010388 GO:0010381 biolink:BiologicalProcess peroxisome-chloroplast membrane tethering The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. go-plus.json attachment of peroxisome to chloroplast http://purl.obolibrary.org/obo/GO_0010381 GO:0010382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010382 GO:0034350 biolink:BiologicalProcess regulation of glial cell apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. go-plus.json regulation of glial cell apoptosis http://purl.obolibrary.org/obo/GO_0034350 GO:0010380 biolink:BiologicalProcess regulation of chlorophyll biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors. go-plus.json http://purl.obolibrary.org/obo/GO_0010380 GO:0034351 biolink:BiologicalProcess negative regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. go-plus.json down-regulation of glial cell apoptosis|downregulation of glial cell apoptosis|down regulation of glial cell apoptosis|inhibition of glial cell apoptosis|negative regulation of glial cell apoptosis http://purl.obolibrary.org/obo/GO_0034351 GO:0034349 biolink:BiologicalProcess glial cell apoptotic process Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. go-plus.json apoptosis of glia|programmed cell death of glia by apoptosis|glia apoptosis|glial cell apoptosis|glial cell programmed cell death by apoptosis|apoptosis of glial cells|programmed cell death of glial cells by apoptosis|programmed cell death, glia|programmed cell death, glial cells|glia programmed cell death by apoptosis http://purl.obolibrary.org/obo/GO_0034349 GO:0034341 biolink:BiologicalProcess response to interferon-gamma Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon. go-plus.json response to immune interferon|response to type II interferon|response to type II IFN|response to gamma-interferon http://purl.obolibrary.org/obo/GO_0034341 GO:0010396 biolink:BiologicalProcess rhamnogalacturonan II metabolic process The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues. go-plus.json rhamnogalacturonan II metabolism http://purl.obolibrary.org/obo/GO_0010396 GO:0034342 biolink:BiologicalProcess response to type III interferon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far. go-plus.json response to type III IFN|response to interferon-lambda http://purl.obolibrary.org/obo/GO_0034342 GO:0010397 biolink:BiologicalProcess apiogalacturonan metabolic process The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links. go-plus.json apiogalacturonan metabolism http://purl.obolibrary.org/obo/GO_0010397 GO:0034343 biolink:BiologicalProcess type III interferon production The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far. go-plus.json type III interferon secretion|type III IFN production http://purl.obolibrary.org/obo/GO_0034343 GO:0010394 biolink:BiologicalProcess homogalacturonan metabolic process The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. go-plus.json homogalacturonan metabolism http://purl.obolibrary.org/obo/GO_0010394 GO:0034344 biolink:BiologicalProcess regulation of type III interferon production Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far. go-plus.json regulation of type III IFN production http://purl.obolibrary.org/obo/GO_0034344 GO:0010395 biolink:BiologicalProcess rhamnogalacturonan I metabolic process The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone. go-plus.json rhamnogalacturonan I metabolism|RGI metabolism http://purl.obolibrary.org/obo/GO_0010395 GO:0034345 biolink:BiologicalProcess negative regulation of type III interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far. go-plus.json downregulation of type III interferon production|down regulation of type III interferon production|inhibition of type III interferon production|negative regulation of type III IFN production|down-regulation of type III interferon production http://purl.obolibrary.org/obo/GO_0034345 GO:0034346 biolink:BiologicalProcess positive regulation of type III interferon production Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far. go-plus.json upregulation of type III interferon production|stimulation of type III interferon production|up-regulation of type III interferon production|activation of type III interferon production|positive regulation of type III IFN production|up regulation of type III interferon production http://purl.obolibrary.org/obo/GO_0034346 GO:0034347 biolink:MolecularActivity type III interferon binding Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far. go-plus.json interferon-lambda binding http://purl.obolibrary.org/obo/GO_0034347 GO:0010398 biolink:BiologicalProcess xylogalacturonan metabolic process The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues. go-plus.json xylogalacturonan metabolism http://purl.obolibrary.org/obo/GO_0010398 GO:0034348 biolink:MolecularActivity type III interferon receptor activity Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far. go-plus.json interferon-lambda receptor activity http://purl.obolibrary.org/obo/GO_0034348 GO:0010399 biolink:BiologicalProcess rhamnogalacturonan I backbone metabolic process The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone. go-plus.json rhamnogalacturonan I backbone metabolism http://purl.obolibrary.org/obo/GO_0010399 GO:0010392 biolink:BiologicalProcess galactoglucomannan metabolic process The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units. go-plus.json galactoglucomannan metabolism http://purl.obolibrary.org/obo/GO_0010392 GO:0010393 biolink:BiologicalProcess galacturonan metabolic process The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues. go-plus.json galacturonan metabolism http://purl.obolibrary.org/obo/GO_0010393 GO:0010390 biolink:BiologicalProcess histone monoubiquitination The modification of histones by addition of a single ubiquitin group. go-plus.json http://purl.obolibrary.org/obo/GO_0010390 CHEBI:1670 biolink:ChemicalSubstance 3-ureidoisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1670 GO:0010391 biolink:BiologicalProcess glucomannan metabolic process The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units. go-plus.json glucomannan metabolism http://purl.obolibrary.org/obo/GO_0010391 GO:0034340 biolink:BiologicalProcess response to type I interferon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json response to type I IFN http://purl.obolibrary.org/obo/GO_0034340 CHEBI:37839 biolink:ChemicalSubstance heterocyclyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37839 CHEBI:37838 biolink:ChemicalSubstance carboacyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37838 UBERON:0014463 biolink:AnatomicalEntity cardiac ganglion Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery. go-plus.json cardiac ganglion of Wrisberg|ganglion of Wrisberg|ganglia cardiaca|Wrisberg ganglion|cardiac ganglia set|cardiac ganglia http://purl.obolibrary.org/obo/UBERON_0014463 UBERON:0014464 biolink:AnatomicalEntity renal fat pad Encapsulated adipose tissue associated with the kidney go-plus.json perirenal fat pad http://purl.obolibrary.org/obo/UBERON_0014464 UBERON:0014466 biolink:AnatomicalEntity subarachnoid fissure go-plus.json http://purl.obolibrary.org/obo/UBERON_0014466 CHEBI:37830 biolink:ChemicalSubstance pentane go-plus.json http://purl.obolibrary.org/obo/CHEBI_37830 chebi_ph7_3 CHEBI:37835 biolink:ChemicalSubstance alkatetraene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37835 CHEBI:13862 biolink:ChemicalSubstance asparagusate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13862 chebi_ph7_3 CHEBI:37834 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraene go-plus.json http://purl.obolibrary.org/obo/CHEBI_37834 chebi_ph7_3 UBERON:0014450 biolink:AnatomicalEntity pretectal nucleus A neural nucleus of the pretectal area (between dorsal thalamus and optic tectum) that receives afferents primarily from the retina and the optic tectum and are involved in modulating motor behavior in response to visual input. go-plus.json pretectal area nucleus|nucleus area pretectalis|pretectal nucleus|nucleus of the pretectal area|nucleus of pretectal area http://purl.obolibrary.org/obo/UBERON_0014450 UBERON:0014451 biolink:AnatomicalEntity tongue taste bud A taste bud that is located on the tongue, situated on a gustatory papilla. go-plus.json gustatory papillae taste bud|gustatory papilla taste bud http://purl.obolibrary.org/obo/UBERON_0014451 CHEBI:23203 biolink:ChemicalSubstance cholestenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_23203 CHEBI:37848 biolink:ChemicalSubstance plant hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_37848 UBERON:0014452 biolink:AnatomicalEntity gustatory epithelium of tongue A gustatory epithelium that is part of a tongue. go-plus.json lingual gustatory epithelium http://purl.obolibrary.org/obo/UBERON_0014452 UBERON:0014453 biolink:AnatomicalEntity gustatory epithelium of palate A gustatory epithelium that is part of a roof of mouth. go-plus.json palatal gustatory epithelium http://purl.obolibrary.org/obo/UBERON_0014453 UBERON:0014454 biolink:AnatomicalEntity visceral abdominal adipose tissue Subcutaneous adipose tissue that is located in the peritoneal cavity. go-plus.json visceral fat|visceral adipose tissue|intra-abdominal adipose tissue|abdominal fat|organ fat|intra-abdominal fat http://purl.obolibrary.org/obo/UBERON_0014454 UBERON:0014455 biolink:AnatomicalEntity subcutaneous abdominal adipose tissue Subcutaneous adipose tissue that is located in the abdominal region. go-plus.json abdominal subcutaneous adipose tissue|subcutaneous abdominal fat|subcutaneous fat of abdominal region http://purl.obolibrary.org/obo/UBERON_0014455 CHEBI:37840 biolink:ChemicalSubstance hydroxyflavone sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37840 CHEBI:37841 biolink:ChemicalSubstance isoprenoid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37841 CHEBI:37846 biolink:ChemicalSubstance imidazo[1,2-a]pyrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37846 chebi_ph7_3 CHEBI:37847 biolink:ChemicalSubstance imidazopyrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37847 CHEBI:13850 biolink:ChemicalSubstance apoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_13850 CHEBI:37810 biolink:ChemicalSubstance octadecatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37810 CHEBI:37814 biolink:ChemicalSubstance dialkylglycerophosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37814 CHEBI:37812 biolink:ChemicalSubstance dialkylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_37812 CHEBI:37826 biolink:ChemicalSubstance sulfuric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_37826 CHEBI:37827 biolink:ChemicalSubstance thiosulfuric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_37827 OBO:chebi#has_functional_parent biolink:OntologyClass has functional parent go-plus.json http://purl.obolibrary.org/obo/chebi#has_functional_parent CHEBI:37806 biolink:ChemicalSubstance penicillanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37806 CHEBI:37807 biolink:ChemicalSubstance ethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_37807 chebi_ph7_3 CHEBI:37808 biolink:ChemicalSubstance butane go-plus.json http://purl.obolibrary.org/obo/CHEBI_37808 chebi_ph7_3 CHEBI:37809 biolink:ChemicalSubstance trans-dec-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37809 UBERON:0014478 biolink:AnatomicalEntity rib skeletal system Subdivision of skeletal system that consists of all ribs and rib joints in an organism. In many vertebrates this consists of the combination of the rib cage and all rib joints, but some vertebrates have ribs outside the thoracic rib cage. go-plus.json set of all ribs|rib series|rib skeleton http://purl.obolibrary.org/obo/UBERON_0014478 UBERON:0014477 biolink:AnatomicalEntity thoracic skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. go-plus.json skeleton of thorax|thoracic skeleton|thoracic part of axial skeleton http://purl.obolibrary.org/obo/UBERON_0014477 CHEBI:23155 biolink:ChemicalSubstance chlorophenylethylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23155 NCBITaxon:213422 biolink:OrganismalEntity Geobacteraceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_213422 CHEBI:23156 biolink:ChemicalSubstance chlorophenylmethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_23156 GO:0010525 biolink:BiologicalProcess regulation of transposition, RNA-mediated Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010525 GO:0010526 biolink:BiologicalProcess negative regulation of transposition, RNA-mediated Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010526 CHEBI:23150 biolink:ChemicalSubstance chlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23150 GO:0010523 biolink:BiologicalProcess negative regulation of calcium ion transport into cytosol Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. go-plus.json http://purl.obolibrary.org/obo/GO_0010523 GO:0010524 biolink:BiologicalProcess positive regulation of calcium ion transport into cytosol Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. go-plus.json http://purl.obolibrary.org/obo/GO_0010524 GO:0010529 biolink:BiologicalProcess negative regulation of transposition Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. go-plus.json http://purl.obolibrary.org/obo/GO_0010529 CHEBI:62761 biolink:ChemicalSubstance tyrosine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_62761 CHEBI:62762 biolink:ChemicalSubstance (+)-2-epi-prezizaene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62762 chebi_ph7_3 CHEBI:23154 biolink:ChemicalSubstance chlorophenylethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_23154 GO:0010527 biolink:BiologicalProcess positive regulation of transposition, RNA-mediated Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010527 CHEBI:23151 biolink:ChemicalSubstance chlorophenoxyacetate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_23151 CHEBI:23152 biolink:ChemicalSubstance chlorophenoxyacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23152 GO:0010528 biolink:BiologicalProcess regulation of transposition Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. go-plus.json http://purl.obolibrary.org/obo/GO_0010528 CHEBI:62760 biolink:ChemicalSubstance (-)-beta-curcumene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62760 chebi_ph7_3 CHEBI:62765 biolink:ChemicalSubstance beta-D-glucosyl crocetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62765 CHEBI:37798 biolink:ChemicalSubstance cyclic phosphorus acid anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_37798 CHEBI:62766 biolink:ChemicalSubstance beta-D-glucosyl crocetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62766 chebi_ph7_3 GO:0009530 biolink:CellularComponent primary cell wall A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present. go-plus.json http://purl.obolibrary.org/obo/GO_0009530 GO:0009531 biolink:CellularComponent secondary cell wall A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin. Wikipedia:Secondary_cell_wall go-plus.json http://purl.obolibrary.org/obo/GO_0009531 CHEBI:62764 biolink:ChemicalSubstance reactive nitrogen species go-plus.json http://purl.obolibrary.org/obo/CHEBI_62764 GO:0009532 biolink:CellularComponent plastid stroma The proteinaceous ground substance of plastids. go-plus.json http://purl.obolibrary.org/obo/GO_0009532 GO:0010521 biolink:MolecularActivity telomerase inhibitor activity Binds to and stops, prevents or reduces the activity of telomerase. go-plus.json http://purl.obolibrary.org/obo/GO_0010521 CHEBI:62769 biolink:ChemicalSubstance beta-D-gentiobiosyl crocetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62769 GO:0009533 biolink:CellularComponent chloroplast stromal thylakoid Unstacked thylakoids that connect the grana stacks through the stroma. go-plus.json http://purl.obolibrary.org/obo/GO_0009533 GO:0010522 biolink:BiologicalProcess regulation of calcium ion transport into cytosol Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. go-plus.json http://purl.obolibrary.org/obo/GO_0010522 GO:0009534 biolink:CellularComponent chloroplast thylakoid Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0009534 CHEBI:62767 biolink:ChemicalSubstance crocetin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62767 chebi_ph7_3 GO:0009535 biolink:CellularComponent chloroplast thylakoid membrane The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0009535 GO:0010520 biolink:BiologicalProcess regulation of reciprocal meiotic recombination Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010520 CHEBI:62768 biolink:ChemicalSubstance bis(beta-D-glucosyl) crocetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62768 chebi_ph7_3 GO:0009536 biolink:CellularComponent plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. Wikipedia:Plastid go-plus.json http://purl.obolibrary.org/obo/GO_0009536 goslim_chembl|goslim_plant|goslim_pir|goslim_generic GO:0009537 biolink:CellularComponent proplastid The precursor of other plastids. go-plus.json http://purl.obolibrary.org/obo/GO_0009537 GO:0009538 biolink:CellularComponent photosystem I reaction center A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin. go-plus.json photosystem I reaction centre http://purl.obolibrary.org/obo/GO_0009538 GO:0009539 biolink:CellularComponent photosystem II reaction center An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone. go-plus.json photosystem II reaction centre http://purl.obolibrary.org/obo/GO_0009539 CHEBI:37794 biolink:ChemicalSubstance aminosulfinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37794 CHEBI:37793 biolink:ChemicalSubstance amino sulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37793 GO:0010536 biolink:BiologicalProcess positive regulation of activation of Janus kinase activity Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. go-plus.json positive regulation of tyrosine phosphorylation of JAK2 protein|positive regulation of tyrosine phosphorylation of JAK1 protein|positive regulation of activation of JAK2 protein|positive regulation of activation of JAK protein|positive regulation of activation of JAK1 protein|positive regulation of activation of JAK2 kinase activity|positive regulation of activation of JAK1 kinase activity|positive regulation of tyrosine phosphorylation of JAK protein http://purl.obolibrary.org/obo/GO_0010536 GO:0010537 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010537 GO:0010534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010534 GO:0010535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010535 GO:0010538 biolink:MolecularActivity obsolete Hsp27 protein regulator activity OBSOLETE. Modulates the activity of the Hsp27 molecular chaperone. go-plus.json Hsp27 protein regulator activity http://purl.obolibrary.org/obo/GO_0010538 CHEBI:23162 biolink:ChemicalSubstance chloropropene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23162 CHEBI:62770 biolink:ChemicalSubstance beta-D-gentiobiosyl crocetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62770 chebi_ph7_3 GO:0010539 biolink:MolecularActivity obsolete Hsp27 protein inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the Hsp27 molecular chaperone. go-plus.json Hsp27 protein inhibitor activity http://purl.obolibrary.org/obo/GO_0010539 CHEBI:62771 biolink:ChemicalSubstance beta-D-gentiobiosyl beta-D-glucosyl crocetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62771 chebi_ph7_3 CHEBI:62776 biolink:ChemicalSubstance (1->4)-beta-D-galactan go-plus.json http://purl.obolibrary.org/obo/CHEBI_62776 chebi_ph7_3 CHEBI:62777 biolink:ChemicalSubstance maltotriulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_62777 chebi_ph7_3 GO:0009540 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009540 GO:0009541 biolink:CellularComponent etioplast prolamellar body A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0009541 GO:0009542 biolink:CellularComponent granum Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0009542 GO:0010532 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010532 GO:0009543 biolink:CellularComponent chloroplast thylakoid lumen The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0009543 GO:0010533 biolink:BiologicalProcess regulation of activation of Janus kinase activity Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. go-plus.json regulation of activation of JAK protein|regulation of tyrosine phosphorylation of JAK2 protein|regulation of tyrosine phosphorylation of JAK protein|regulation of tyrosine phosphorylation of JAK1 protein|regulation of activation of JAK2 protein|regulation of activation of JAK1 protein|regulation of activation of JAK2 kinase activity|regulation of activation of JAK1 kinase activity http://purl.obolibrary.org/obo/GO_0010533 GO:0009544 biolink:CellularComponent chloroplast ATP synthase complex The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts. go-plus.json http://purl.obolibrary.org/obo/GO_0009544 GO:0009545 biolink:CellularComponent elaioplast A leucoplast in which oil is stored. Wikipedia:Elaioplast go-plus.json http://purl.obolibrary.org/obo/GO_0009545 GO:0010530 biolink:BiologicalProcess positive regulation of transposition Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. go-plus.json http://purl.obolibrary.org/obo/GO_0010530 GO:0009546 biolink:CellularComponent plasmodesmatal cytoplasmic sleeve The space between the plasma membrane and the desmotubule of a plasmodesma. go-plus.json plasmodesmatal cytoplasmic annulus http://purl.obolibrary.org/obo/GO_0009546 GO:0010531 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010531 GO:0009547 biolink:CellularComponent plastid ribosome A ribosome contained within a plastid. go-plus.json http://purl.obolibrary.org/obo/GO_0009547 GO:0009548 biolink:CellularComponent plasmodesmatal plasma membrane The portion of the plasma membrane surrounding a plasmodesma. go-plus.json http://purl.obolibrary.org/obo/GO_0009548 GO:0009549 biolink:CellularComponent cellulose microfibril A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0009549 CHEBI:23135 biolink:ChemicalSubstance chlorobenzophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23135 CHEBI:23136 biolink:ChemicalSubstance chlorobenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_23136 GO:0010509 biolink:BiologicalProcess polyamine homeostasis Any biological process involved in the maintenance of an internal steady state of a polyamine. go-plus.json http://purl.obolibrary.org/obo/GO_0010509 CHEBI:23133 biolink:ChemicalSubstance chlorobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23133 CHEBI:23134 biolink:ChemicalSubstance chlorobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23134 CHEBI:23139 biolink:ChemicalSubstance chlorocyclohexene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23139 NCBITaxon:1883 biolink:OrganismalEntity Streptomyces go-plus.json Chainia http://purl.obolibrary.org/obo/NCBITaxon_1883 CHEBI:23138 biolink:ChemicalSubstance chlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23138 GO:0010503 biolink:BiologicalProcess obsolete negative regulation of cell cycle arrest in response to nitrogen starvation OBSOLETE. Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0010503 GO:0010504 biolink:BiologicalProcess obsolete regulation of cell cycle arrest in response to nitrogen starvation OBSOLETE. Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0010504 CHEBI:62780 biolink:ChemicalSubstance alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_62780 chebi_ph7_3 GO:0010501 biolink:BiologicalProcess RNA secondary structure unwinding The process in which a secondary structure of RNA are broken or 'melted'. go-plus.json RNA duplex unwinding http://purl.obolibrary.org/obo/GO_0010501 GO:0010502 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010502 GO:0010507 biolink:BiologicalProcess negative regulation of autophagy Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0010507 CHEBI:62783 biolink:ChemicalSubstance beta-D-Xylp-(1->4)-beta-D-Xylp-(1->4)-D-Xylp go-plus.json http://purl.obolibrary.org/obo/CHEBI_62783 chebi_ph7_3 GO:0010508 biolink:BiologicalProcess positive regulation of autophagy Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0010508 CHEBI:23132 biolink:ChemicalSubstance chlorobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23132 GO:0010505 biolink:BiologicalProcess obsolete positive regulation of cell cycle arrest in response to nitrogen starvation OBSOLETE. Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0010505 CHEBI:62781 biolink:ChemicalSubstance alpha-L-Araf-(1->5)-alpha-L-Araf-(1->5)-L-Araf go-plus.json http://purl.obolibrary.org/obo/CHEBI_62781 chebi_ph7_3 GO:0010506 biolink:BiologicalProcess regulation of autophagy Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0010506 CHEBI:23130 biolink:ChemicalSubstance chloroaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_23130 CHEBI:62787 biolink:ChemicalSubstance 1,5-dihydroflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_62787 chebi_ph7_3 CHEBI:62788 biolink:ChemicalSubstance 3-nonaprenyl-4,5-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62788 CHEBI:62785 biolink:ChemicalSubstance beta-D-Manp-(1->4)-beta-D-Manp-(1->4)-D-Manp go-plus.json http://purl.obolibrary.org/obo/CHEBI_62785 chebi_ph7_3 GO:0009510 biolink:CellularComponent plasmodesmatal desmotubule A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell. go-plus.json desmotubule central rod http://purl.obolibrary.org/obo/GO_0009510 GO:0009511 biolink:CellularComponent plasmodesmatal endoplasmic reticulum Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells. go-plus.json plasmodesmatal ER http://purl.obolibrary.org/obo/GO_0009511 GO:0010500 biolink:BiologicalProcess transmitting tissue development The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary. go-plus.json http://purl.obolibrary.org/obo/GO_0010500 GO:0009512 biolink:CellularComponent cytochrome b6f complex Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species. Wikipedia:Cytochrome_b6f_complex go-plus.json cytochrome b6-f complex|cytochrome b6/f complex|cytochrome b(6)f complex|cyt b6f complex|cyt b6-f complex|cyt b6/f complex|cyt b(6)f complex http://purl.obolibrary.org/obo/GO_0009512 CHEBI:62789 biolink:ChemicalSubstance 3-nonaprenyl-4,5-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62789 chebi_ph7_3 GO:0009513 biolink:CellularComponent etioplast A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions. Wikipedia:Etioplast go-plus.json http://purl.obolibrary.org/obo/GO_0009513 GO:0009514 biolink:CellularComponent glyoxysome A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds. Wikipedia:Glyoxysome go-plus.json http://purl.obolibrary.org/obo/GO_0009514 GO:0009515 biolink:CellularComponent granal stacked thylakoid Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II. go-plus.json chloroplast stacked thylakoid http://purl.obolibrary.org/obo/GO_0009515 GO:0009516 biolink:CellularComponent leucoplast A colorless plastid involved in the synthesis of monoterpenes. Wikipedia:Leucoplast go-plus.json http://purl.obolibrary.org/obo/GO_0009516 GO:0009517 biolink:CellularComponent PSII associated light-harvesting complex II Protein-pigment complex associated with photosystem II. go-plus.json LHCII http://purl.obolibrary.org/obo/GO_0009517 GO:0009518 biolink:CellularComponent PSI associated light-harvesting complex I Protein-pigment complex associated with photosystem I. go-plus.json LHCI http://purl.obolibrary.org/obo/GO_0009518 CHEBI:37773 biolink:ChemicalSubstance organic phosphoramidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37773 GO:0009519 biolink:CellularComponent middle lamella Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells. Wikipedia:Middle_lamella go-plus.json http://purl.obolibrary.org/obo/GO_0009519 CHEBI:23147 biolink:ChemicalSubstance chlorohydroquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_23147 CHEBI:23148 biolink:ChemicalSubstance chloromethanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23148 CHEBI:62790 biolink:ChemicalSubstance 3-nonaprenyl-4-hydroxy-5-methoxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_62790 GO:0010514 biolink:BiologicalProcess induction of conjugation with cellular fusion The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types. go-plus.json http://purl.obolibrary.org/obo/GO_0010514 CHEBI:62791 biolink:ChemicalSubstance 3-nonaprenyl-4-hydroxy-5-methoxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62791 chebi_ph7_3 GO:0010515 biolink:BiologicalProcess negative regulation of induction of conjugation with cellular fusion Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0010515 GO:0010512 biolink:BiologicalProcess negative regulation of phosphatidylinositol biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0010512 GO:0010513 biolink:BiologicalProcess positive regulation of phosphatidylinositol biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0010513 GO:0010518 biolink:BiologicalProcess positive regulation of phospholipase activity Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0010518 CHEBI:23142 biolink:ChemicalSubstance chloroethenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23142 GO:0010519 biolink:BiologicalProcess negative regulation of phospholipase activity Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0010519 GO:0010516 biolink:BiologicalProcess negative regulation of cellular response to nitrogen starvation Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0010516 CHEBI:23140 biolink:ChemicalSubstance chlorodienelactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23140 CHEBI:62793 biolink:ChemicalSubstance 3-decaprenyl-4,5-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62793 chebi_ph7_3 GO:0010517 biolink:BiologicalProcess regulation of phospholipase activity Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0010517 CHEBI:23141 biolink:ChemicalSubstance chloroethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23141 CHEBI:37787 biolink:ChemicalSubstance acyclic mixed acid anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_37787 CHEBI:37788 biolink:ChemicalSubstance O(4)-phospho-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37788 CHEBI:62796 biolink:ChemicalSubstance 3-decaprenyl-4-hydroxy-5-methoxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62796 chebi_ph7_3 CHEBI:37785 biolink:ChemicalSubstance organosulfinate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_37785 chebi_ph7_3 GO:0009520 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009520 CHEBI:37786 biolink:ChemicalSubstance acyclic phosphorus acid anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_37786 GO:0010510 biolink:BiologicalProcess regulation of acetyl-CoA biosynthetic process from pyruvate Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. go-plus.json http://purl.obolibrary.org/obo/GO_0010510 GO:0009521 biolink:CellularComponent photosystem A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species. Wikipedia:Photosystem go-plus.json reaction centre|reaction center http://purl.obolibrary.org/obo/GO_0009521 goslim_pir GO:0010511 biolink:BiologicalProcess regulation of phosphatidylinositol biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0010511 GO:0009522 biolink:CellularComponent photosystem I A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation). go-plus.json http://purl.obolibrary.org/obo/GO_0009522 GO:0009523 biolink:CellularComponent photosystem II A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center. Wikipedia:Photosystem_II go-plus.json http://purl.obolibrary.org/obo/GO_0009523 GO:0009524 biolink:CellularComponent phragmoplast Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules. Wikipedia:Phragmoplast go-plus.json http://purl.obolibrary.org/obo/GO_0009524 GO:0009525 biolink:CellularComponent phragmosome A flattened membranous vesicle containing cell wall components. Wikipedia:Phragmosome go-plus.json http://purl.obolibrary.org/obo/GO_0009525 GO:0009526 biolink:CellularComponent plastid envelope The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0009526 GO:0009527 biolink:CellularComponent plastid outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0009527 GO:0009528 biolink:CellularComponent plastid inner membrane The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma. go-plus.json http://purl.obolibrary.org/obo/GO_0009528 GO:0009529 biolink:CellularComponent plastid intermembrane space The region between the inner and outer lipid bilayers of the plastid envelope. go-plus.json plastid envelope lumen http://purl.obolibrary.org/obo/GO_0009529 CHEBI:37783 biolink:ChemicalSubstance organosulfinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37783 CHEBI:37784 biolink:ChemicalSubstance sulfinic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_37784 CHEBI:23114 biolink:ChemicalSubstance chloride salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_23114 CHEBI:23117 biolink:ChemicalSubstance chlorine molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_23117 CHEBI:23115 biolink:ChemicalSubstance chlorohydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_23115 CHEBI:23116 biolink:ChemicalSubstance chlorine atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_23116 chebi_ph7_3 OBA:VT0015071 biolink:OntologyClass appendage morphology trait The morphology of a appendage. go-plus.json morphology of appendage http://purl.obolibrary.org/obo/OBA_VT0015071 OBA:VT0015074 biolink:OntologyClass organ system trait The quality when measured in anatomical system. go-plus.json http://purl.obolibrary.org/obo/OBA_VT0015074 UBERON:0014540 biolink:AnatomicalEntity white matter lamina of cerebellum The white laminae of cerebellum is subdivision of the cerebellar cortex comprised of myelinated axons lying deep to the granule cell layer of the cerebellar cortex. go-plus.json white lamina of cerebellum|laminae albae of cerebellar cortex|isthmus of the cingulate gyrus|laminae albae of cerebellar cortex|isthmus-2|isthmus gyri cinguli|lamina alba of cerebellar cortex|isthmus gyri cingulatus|white laminae of cerebellum|isthmus of gyrus fornicatus|isthmus cinguli http://purl.obolibrary.org/obo/UBERON_0014540 UBERON:0014541 biolink:AnatomicalEntity thoracic division of spinal cord central canal Part of spinal cord central canal contained in the thoracic spinal cord. It is continuous rostrally with the cervical spinal cord central canal and caudally with the lumbar spinal cord central canal. go-plus.json thoracic spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014541 UBERON:0014542 biolink:AnatomicalEntity cervical division of cord spinal central canal Part of central canal contained within the cervical spinal cord. It is continuous caudally with the thoracic spinal cord central canal and rostrally with the fourth ventricle of the brain via the obex go-plus.json cervical spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014542 CHEBI:37754 biolink:ChemicalSubstance 6-hydroxypseudooxynicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37754 CHEBI:37755 biolink:ChemicalSubstance 4-(methylamino)butyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37755 CHEBI:37753 biolink:ChemicalSubstance pseudooxynicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37753 UBERON:0014538 biolink:AnatomicalEntity subdivision of spinal cord central canal A subdivision of the central canal of the spinal cord along its anterior-posterior axis. This is typically subdivided into cervical, thoracic, lumbar and sacral segments go-plus.json regional part of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014538 CHEBI:37757 biolink:ChemicalSubstance iodoalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_37757 CHEBI:37750 biolink:ChemicalSubstance chlorine oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37750 CHEBI:23123 biolink:ChemicalSubstance chloroacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23123 chebi_ph7_3 CHEBI:23128 biolink:ChemicalSubstance chloroalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_23128 CHEBI:23129 biolink:ChemicalSubstance chloroamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23129 CHEBI:23127 biolink:ChemicalSubstance chloroalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23127 UBERON:0014530 biolink:AnatomicalEntity white matter lamina of neuraxis go-plus.json neuraxis lamina|lamina of neuraxis http://purl.obolibrary.org/obo/UBERON_0014530 UBERON:0014531 biolink:AnatomicalEntity white matter lamina of diencephalon go-plus.json diencephalon lamina|lamina of diencephalon http://purl.obolibrary.org/obo/UBERON_0014531 UBERON:0014532 biolink:AnatomicalEntity white matter lamina of cerebral hemisphere go-plus.json cerebral hemisphere lamina|lamina of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0014532 CHEBI:37763 biolink:ChemicalSubstance elemental silicon go-plus.json http://purl.obolibrary.org/obo/CHEBI_37763 GO:0009500 biolink:MolecularActivity obsolete dicluster bacterial-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json dicluster bacterial-type ferredoxin http://purl.obolibrary.org/obo/GO_0009500 GO:0009501 biolink:CellularComponent amyloplast A plastid whose main function is to synthesize and store starch. Wikipedia:Amyloplast go-plus.json http://purl.obolibrary.org/obo/GO_0009501 GO:0009502 biolink:CellularComponent obsolete photosynthetic electron transport chain OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen). go-plus.json photosynthetic electron transport chain http://purl.obolibrary.org/obo/GO_0009502 GO:0009503 biolink:CellularComponent thylakoid light-harvesting complex A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0009503 GO:0009504 biolink:CellularComponent cell plate The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells. Wikipedia:Cell_plate go-plus.json http://purl.obolibrary.org/obo/GO_0009504 GO:0009505 biolink:CellularComponent plant-type cell wall A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances. go-plus.json plant cell wall|cellulose and pectin-containing cell wall http://purl.obolibrary.org/obo/GO_0009505 GO:0009506 biolink:CellularComponent plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. Wikipedia:Plasmodesma go-plus.json plasmodesmata http://purl.obolibrary.org/obo/GO_0009506 GO:0009507 biolink:CellularComponent chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. Wikipedia:Chloroplast go-plus.json http://purl.obolibrary.org/obo/GO_0009507 goslim_plant GO:0009508 biolink:CellularComponent plastid chromosome A circular DNA molecule containing plastid encoded genes. go-plus.json http://purl.obolibrary.org/obo/GO_0009508 GO:0009509 biolink:CellularComponent chromoplast A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments. Wikipedia:Chromoplast go-plus.json http://purl.obolibrary.org/obo/GO_0009509 CHEBI:37738 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37738 CHEBI:37739 biolink:ChemicalSubstance glycerophospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_37739 CHEBI:37733 biolink:ChemicalSubstance EC 3.1.1.8 (cholinesterase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_37733 CHEBI:37736 biolink:ChemicalSubstance D-fructofuranose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37736 CHEBI:37737 biolink:ChemicalSubstance 5-phospho-beta-D-ribosylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37737 CHEBI:37734 biolink:ChemicalSubstance phosphoric ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_37734 CHEBI:37735 biolink:ChemicalSubstance phosphonic ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_37735 CHEBI:23102 biolink:ChemicalSubstance chitobiosyldiphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23102 CHEBI:23101 biolink:ChemicalSubstance N,N'-diacetylchitobioses go-plus.json http://purl.obolibrary.org/obo/CHEBI_23101 CHEBI:37749 biolink:ChemicalSubstance halogen oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_37749 CHEBI:37741 biolink:ChemicalSubstance L-allopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37741 chebi_ph7_3 CHEBI:37742 biolink:ChemicalSubstance allopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37742 CHEBI:37747 biolink:ChemicalSubstance L-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37747 CHEBI:37748 biolink:ChemicalSubstance aldehydo-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37748 CHEBI:13796 biolink:ChemicalSubstance S-polyprenyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_13796 CHEBI:37746 biolink:ChemicalSubstance aldehydo-L-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37746 chebi_ph7_3 CHEBI:13790 biolink:ChemicalSubstance N-acetylarylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_13790 chebi_ph7_3 CHEBI:13792 biolink:ChemicalSubstance N-hydroxyarylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_13792 chebi_ph7_3 CHEBI:37740 biolink:ChemicalSubstance beta-L-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37740 chebi_ph7_3 GO:0034572 biolink:MolecularActivity monodemethylisoproturon dimethylaminedehydrogenase activity Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-. UM-BBD_reactionID:r0897|EC:1.5.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034572 GO:0034573 biolink:MolecularActivity didemethylisoproturon amidohydrolase activity Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline. UM-BBD_reactionID:r0898 go-plus.json http://purl.obolibrary.org/obo/GO_0034573 GO:0034574 biolink:MolecularActivity didemethylisoproturon dehydrogenase activity Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-. UM-BBD_reactionID:r0899|EC:1.17.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034574 GO:0034575 biolink:MolecularActivity 4-isopropylaniline dehydrogenase activity Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-. EC:1.17.99.-|UM-BBD_reactionID:r0901 go-plus.json http://purl.obolibrary.org/obo/GO_0034575 GO:0034576 biolink:MolecularActivity N-isopropylacetanilide amidohydrolase activity Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate. UM-BBD_reactionID:r0913 go-plus.json http://purl.obolibrary.org/obo/GO_0034576 GO:0034577 biolink:MolecularActivity N-isopropylacetaniline monooxygenase activity Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone. UM-BBD_reactionID:r0914|EC:1.14.15.- go-plus.json http://purl.obolibrary.org/obo/GO_0034577 GO:0034578 biolink:MolecularActivity limonene 8-hydratase activity Catalysis of the reaction: limonene + H2O = alpha-terpineol. UM-BBD_reactionID:r0916 go-plus.json http://purl.obolibrary.org/obo/GO_0034578 GO:0034579 biolink:MolecularActivity (1-methylpentyl)succinate synthase activity Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate. UM-BBD_reactionID:r0920 go-plus.json http://purl.obolibrary.org/obo/GO_0034579 GO:0034570 biolink:MolecularActivity hydroxymonomethylisoproturon dimethylaminedehydrogenase activity Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-. EC:1.5.99.-|UM-BBD_reactionID:r0894 go-plus.json http://purl.obolibrary.org/obo/GO_0034570 GO:0034571 biolink:MolecularActivity 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid. UM-BBD_reactionID:r0895 go-plus.json http://purl.obolibrary.org/obo/GO_0034571 GO:0034569 biolink:MolecularActivity monodemethylisoproturon dehydrogenase activity Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-. EC:1.17.99.-|UM-BBD_reactionID:r0893 go-plus.json http://purl.obolibrary.org/obo/GO_0034569 GO:0034561 biolink:MolecularActivity 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O. UM-BBD_reactionID:r0862 go-plus.json http://purl.obolibrary.org/obo/GO_0034561 GO:0034562 biolink:MolecularActivity 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O. UM-BBD_reactionID:r0864 go-plus.json http://purl.obolibrary.org/obo/GO_0034562 GO:0034563 biolink:MolecularActivity 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-. UM-BBD_reactionID:r0867 go-plus.json http://purl.obolibrary.org/obo/GO_0034563 GO:0034564 biolink:MolecularActivity 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-. UM-BBD_reactionID:r0866 go-plus.json http://purl.obolibrary.org/obo/GO_0034564 GO:0034565 biolink:MolecularActivity 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol. EC:3.5.99.-|UM-BBD_reactionID:r0872 go-plus.json http://purl.obolibrary.org/obo/GO_0034565 GO:0034566 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034566 GO:0034567 biolink:MolecularActivity chromate reductase activity Catalysis of the reaction: chromate = chromium (III). EC:1.97.1.-|UM-BBD_reactionID:r0884 go-plus.json http://purl.obolibrary.org/obo/GO_0034567 GO:0034568 biolink:MolecularActivity isoproturon dimethylaminedehydrogenase activity Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-. EC:1.5.99.-|UM-BBD_reactionID:r0892 go-plus.json http://purl.obolibrary.org/obo/GO_0034568 GO:0034560 biolink:MolecularActivity bisphenol A hydroxylase A activity Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O. EC:1.14.13.-|UM-BBD_reactionID:r0861 go-plus.json http://purl.obolibrary.org/obo/GO_0034560 GO:0034558 biolink:MolecularActivity technetium (VII) reductase activity Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-. UM-BBD_reactionID:r0859 go-plus.json http://purl.obolibrary.org/obo/GO_0034558 GO:0034559 biolink:MolecularActivity bisphenol A hydroxylase B activity Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O. UM-BBD_reactionID:r0860 go-plus.json http://purl.obolibrary.org/obo/GO_0034559 GO:0010589 biolink:BiologicalProcess leaf proximal/distal pattern formation The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis. go-plus.json http://purl.obolibrary.org/obo/GO_0010589 GO:0034550 biolink:MolecularActivity dimethylarsinate reductase activity Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O. UM-BBD_reactionID:r0838|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034550 GO:0009594 biolink:BiologicalProcess detection of nutrient The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal. go-plus.json detection of nutrients|perception of nutrients|nutrient sensing http://purl.obolibrary.org/obo/GO_0009594 GO:0010583 biolink:BiologicalProcess response to cyclopentenone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0010583 GO:0034551 biolink:BiologicalProcess mitochondrial respiratory chain complex III assembly The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane. go-plus.json mitochondrial cytochrome bc(1) complex assembly http://purl.obolibrary.org/obo/GO_0034551 GO:0009595 biolink:BiologicalProcess detection of biotic stimulus The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal. go-plus.json perception of biotic stimulus http://purl.obolibrary.org/obo/GO_0009595 GO:0010584 biolink:BiologicalProcess pollen exine formation The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine. go-plus.json http://purl.obolibrary.org/obo/GO_0010584 GO:0010581 biolink:BiologicalProcess regulation of starch biosynthetic process An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch. go-plus.json http://purl.obolibrary.org/obo/GO_0010581 GO:0034552 biolink:BiologicalProcess respiratory chain complex II assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II. go-plus.json http://purl.obolibrary.org/obo/GO_0034552 GO:0009596 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009596 GO:0034553 biolink:BiologicalProcess mitochondrial respiratory chain complex II assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034553 GO:0010582 biolink:BiologicalProcess floral meristem determinacy The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate). go-plus.json http://purl.obolibrary.org/obo/GO_0010582 GO:0009597 biolink:BiologicalProcess detection of virus The series of events in which a stimulus from a virus is received and converted into a molecular signal. go-plus.json perception of virus http://purl.obolibrary.org/obo/GO_0009597 GO:0009598 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009598 GO:0010587 biolink:BiologicalProcess miRNA catabolic process The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. go-plus.json microRNA catabolic process http://purl.obolibrary.org/obo/GO_0010587 GO:0034554 biolink:MolecularActivity 3,3',5-tribromobisphenol A reductive dehalogenase activity Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr. EC:1.97.1.-|UM-BBD_reactionID:r0842 go-plus.json http://purl.obolibrary.org/obo/GO_0034554 GO:0009599 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009599 GO:0034555 biolink:MolecularActivity 3,3'-dibromobisphenol A reductive dehalogenase activity Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr. EC:1.97.1.-|UM-BBD_reactionID:r0844 go-plus.json http://purl.obolibrary.org/obo/GO_0034555 GO:0010588 biolink:BiologicalProcess cotyledon vascular tissue pattern formation Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants. go-plus.json http://purl.obolibrary.org/obo/GO_0010588 GO:0010585 biolink:BiologicalProcess glutamine secretion The controlled release of glutamine by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010585 GO:0034556 biolink:MolecularActivity nitrobenzoate nitroreductase activity Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+. EC:1.7.1.-|UM-BBD_reactionID:r0849 go-plus.json http://purl.obolibrary.org/obo/GO_0034556 GO:0034557 biolink:MolecularActivity 2-hydroxylaminobenzoate reductase activity Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O. UM-BBD_reactionID:r0850|MetaCyc:RXN-8848 go-plus.json o-hydroxylaminobenzoate nitroreductase activity http://purl.obolibrary.org/obo/GO_0034557 GO:0010586 biolink:BiologicalProcess miRNA metabolic process The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. go-plus.json microRNA metabolic process http://purl.obolibrary.org/obo/GO_0010586 goslim_drosophila GO:0010580 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010580 GO:0034547 biolink:MolecularActivity N-cyclopropylmelamine deaminase activity Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3. UM-BBD_reactionID:r0825|MetaCyc:RXN-8018 go-plus.json http://purl.obolibrary.org/obo/GO_0034547 GO:0034548 biolink:MolecularActivity N-cyclopropylammeline deaminase activity Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3. UM-BBD_reactionID:r0826|MetaCyc:RXN-8019 go-plus.json http://purl.obolibrary.org/obo/GO_0034548 GO:0034549 biolink:MolecularActivity N-cyclopropylammelide alkylamino hydrolase activity Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid. UM-BBD_reactionID:r0827|MetaCyc:RXN-8020|KEGG_REACTION:R06972 go-plus.json http://purl.obolibrary.org/obo/GO_0034549 GO:0010594 biolink:BiologicalProcess regulation of endothelial cell migration Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0010594 GO:0010595 biolink:BiologicalProcess positive regulation of endothelial cell migration Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0010595 GO:0034540 biolink:MolecularActivity 3-monobromobisphenol A reductive dehalogenase activity Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr. EC:1.97.1.-|UM-BBD_reactionID:r0824 go-plus.json http://purl.obolibrary.org/obo/GO_0034540 GO:0034541 biolink:MolecularActivity dimethylarsinite methyltransferase activity Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH. UM-BBD_reactionID:r0806 go-plus.json http://purl.obolibrary.org/obo/GO_0034541 GO:0010592 biolink:BiologicalProcess positive regulation of lamellipodium assembly Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. go-plus.json positive regulation of lamellipodium biogenesis http://purl.obolibrary.org/obo/GO_0010592 GO:0010593 biolink:BiologicalProcess negative regulation of lamellipodium assembly Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. go-plus.json negative regulation of lamellipodium biogenesis http://purl.obolibrary.org/obo/GO_0010593 GO:0034542 biolink:MolecularActivity trimethylarsine oxidase activity Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O. UM-BBD_reactionID:r0807|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034542 GO:0034543 biolink:MolecularActivity 5-aminosalicylate dioxygenase activity Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate. UM-BBD_reactionID:r0809|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034543 GO:0010598 biolink:CellularComponent NAD(P)H dehydrogenase complex (plastoquinone) Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool. go-plus.json http://purl.obolibrary.org/obo/GO_0010598 GO:0010599 biolink:BiologicalProcess production of lsiRNA involved in RNA interference Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions. go-plus.json RNA interference, production of lsiRNA http://purl.obolibrary.org/obo/GO_0010599 GO:0034544 biolink:MolecularActivity trans-ACOHDA hydrolase activity Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3. UM-BBD_reactionID:r0810|EC:3.5.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034544 GO:0010596 biolink:BiologicalProcess negative regulation of endothelial cell migration Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0010596 GO:0034545 biolink:MolecularActivity fumarylpyruvate hydrolase activity Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+. UM-BBD_reactionID:r0811|EC:3.7.1.20|RHEA:26168 go-plus.json http://purl.obolibrary.org/obo/GO_0034545 GO:0034546 biolink:MolecularActivity 2,4-dichloroaniline reductive dehalogenase activity Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl. UM-BBD_reactionID:r0819|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034546 GO:0010597 biolink:BiologicalProcess green leaf volatile biosynthetic process The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0010597 GO:0010590 biolink:BiologicalProcess regulation of septum digestion after cytokinesis Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. go-plus.json regulation of cell separation after cytokinesis|regulation of cell separation following cytokinesis|regulation of mitotic cytokinetic cell separation http://purl.obolibrary.org/obo/GO_0010590 GO:0010591 biolink:BiologicalProcess regulation of lamellipodium assembly Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. go-plus.json regulation of lamellipodium biogenesis http://purl.obolibrary.org/obo/GO_0010591 GO:0034536 biolink:MolecularActivity 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate. EC:5.3.99.-|UM-BBD_reactionID:r0782 go-plus.json http://purl.obolibrary.org/obo/GO_0034536 GO:0010569 biolink:BiologicalProcess regulation of double-strand break repair via homologous recombination Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. go-plus.json http://purl.obolibrary.org/obo/GO_0010569 GO:0034537 biolink:MolecularActivity 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde. UM-BBD_reactionID:r0783 go-plus.json http://purl.obolibrary.org/obo/GO_0034537 GO:0034538 biolink:MolecularActivity 3-methylsalicylaldehyde dehydrogenase activity Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+. UM-BBD_reactionID:r0784 go-plus.json http://purl.obolibrary.org/obo/GO_0034538 GO:0010567 biolink:BiologicalProcess regulation of ketone catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010567 GO:0010568 biolink:BiologicalProcess regulation of budding cell apical bud growth Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding. go-plus.json http://purl.obolibrary.org/obo/GO_0010568 GO:0034539 biolink:MolecularActivity 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr. UM-BBD_reactionID:r0821|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034539 CHEBI:23197 biolink:ChemicalSubstance cholestanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_23197 GO:0009580 biolink:CellularComponent obsolete thylakoid (sensu Bacteria) OBSOLETE. (Was not defined before being made obsolete). go-plus.json thylakoid (sensu Bacteria) http://purl.obolibrary.org/obo/GO_0009580 GO:0009581 biolink:BiologicalProcess detection of external stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of external stimulus http://purl.obolibrary.org/obo/GO_0009581 GO:0009582 biolink:BiologicalProcess detection of abiotic stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of abiotic stimulus http://purl.obolibrary.org/obo/GO_0009582 GO:0009572 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009572 GO:0010561 biolink:BiologicalProcess negative regulation of glycoprotein biosynthetic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_0010561 GO:0009573 biolink:CellularComponent chloroplast ribulose bisphosphate carboxylase complex A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana. go-plus.json chloroplast RubisCO complex http://purl.obolibrary.org/obo/GO_0009573 GO:0010562 biolink:BiologicalProcess positive regulation of phosphorus metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. go-plus.json http://purl.obolibrary.org/obo/GO_0010562 GO:0009574 biolink:CellularComponent preprophase band A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs. Wikipedia:Preprophase_band go-plus.json http://purl.obolibrary.org/obo/GO_0009574 GO:0034530 biolink:MolecularActivity 4-hydroxymethylsalicyaldehyde dehydrogenase activity Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+. EC:1.2.1.-|UM-BBD_reactionID:r0767 go-plus.json http://purl.obolibrary.org/obo/GO_0034530 GO:0034531 biolink:MolecularActivity 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde. UM-BBD_reactionID:r0766 go-plus.json http://purl.obolibrary.org/obo/GO_0034531 GO:0009575 biolink:CellularComponent chromoplast stroma The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material. go-plus.json http://purl.obolibrary.org/obo/GO_0009575 GO:0010560 biolink:BiologicalProcess positive regulation of glycoprotein biosynthetic process Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_0010560 GO:0034532 biolink:MolecularActivity 2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate. UM-BBD_reactionID:r0765|EC:5.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034532 GO:0009576 biolink:CellularComponent leucoplast stroma The space enclosed by the double membrane of a leucoplast. go-plus.json http://purl.obolibrary.org/obo/GO_0009576 GO:0010565 biolink:BiologicalProcess regulation of cellular ketone metabolic process Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0010565 GO:0009577 biolink:CellularComponent elaioplast stroma The space enclosed by the double membrane of an elaioplast. go-plus.json http://purl.obolibrary.org/obo/GO_0009577 GO:0034533 biolink:MolecularActivity 1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate. UM-BBD_reactionID:r0764 go-plus.json http://purl.obolibrary.org/obo/GO_0034533 GO:0010566 biolink:BiologicalProcess regulation of ketone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010566 GO:0034534 biolink:MolecularActivity 1-methylnaphthalene hydroxylase activity Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O. EC:1.14.13.-|UM-BBD_reactionID:r0795 go-plus.json http://purl.obolibrary.org/obo/GO_0034534 GO:0009578 biolink:CellularComponent etioplast stroma The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0009578 GO:0010563 biolink:BiologicalProcess negative regulation of phosphorus metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. go-plus.json http://purl.obolibrary.org/obo/GO_0010563 GO:0009579 biolink:CellularComponent thylakoid A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. Wikipedia:Thylakoid go-plus.json photosynthetic membrane http://purl.obolibrary.org/obo/GO_0009579 goslim_plant|goslim_pir|goslim_metagenomics|goslim_generic|goslim_chembl GO:0010564 biolink:BiologicalProcess regulation of cell cycle process Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. go-plus.json http://purl.obolibrary.org/obo/GO_0010564 GO:0034535 biolink:MolecularActivity 1,2-dihydroxy-8-methylnaphthalene dioxygenase activity Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+. UM-BBD_reactionID:r0781 go-plus.json http://purl.obolibrary.org/obo/GO_0034535 CHEBI:62729 biolink:ChemicalSubstance 3-(all-trans-polyprenyl)benzene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62729 chebi_ph7_3 CHEBI:62727 biolink:ChemicalSubstance molybdopterin adenine dinucleotide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_62727 chebi_ph7_3 CHEBI:62728 biolink:ChemicalSubstance molybdopterin adenine dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62728 GO:0034525 biolink:MolecularActivity 1-naphthaldehyde dehydrogenase activity Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+. UM-BBD_reactionID:r0787 go-plus.json http://purl.obolibrary.org/obo/GO_0034525 GO:0034526 biolink:MolecularActivity 2-methylnaphthalene hydroxylase activity Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O. EC:1.14.13.-|UM-BBD_reactionID:r0788 go-plus.json http://purl.obolibrary.org/obo/GO_0034526 GO:0034527 biolink:MolecularActivity 1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene. UM-BBD_reactionID:r0790 go-plus.json http://purl.obolibrary.org/obo/GO_0034527 GO:0010578 biolink:BiologicalProcess regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway. go-plus.json regulation of adenylate cyclase activity involved in G-protein signaling pathway|regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|regulation of adenylate cyclase activity involved in G-protein signalling http://purl.obolibrary.org/obo/GO_0010578 GO:0034528 biolink:MolecularActivity 2-carboxy-2-hydroxy-8-carboxychromene isomerase activity Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate. EC:5.3.99.-|UM-BBD_reactionID:r0791 go-plus.json http://purl.obolibrary.org/obo/GO_0034528 GO:0010579 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010579 GO:0034529 biolink:MolecularActivity 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate. UM-BBD_reactionID:r0792 go-plus.json http://purl.obolibrary.org/obo/GO_0034529 GO:0009590 biolink:BiologicalProcess detection of gravity The series of events in which a gravitational stimulus is received and converted into a molecular signal. go-plus.json perception of gravity http://purl.obolibrary.org/obo/GO_0009590 GO:0009591 biolink:BiologicalProcess obsolete perception of mechanical stimulus OBSOLETE. The series of events by which a mechanical stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of mechanical stimulus http://purl.obolibrary.org/obo/GO_0009591 GO:0009592 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009592 GO:0009593 biolink:BiologicalProcess detection of chemical stimulus The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of chemical stimulus|detection of chemical substance|perception of chemical substance|chemoreception|chemoperception http://purl.obolibrary.org/obo/GO_0009593 GO:0010572 biolink:BiologicalProcess positive regulation of platelet activation Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0010572 GO:0009583 biolink:BiologicalProcess detection of light stimulus The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. go-plus.json detection of light|perception of light http://purl.obolibrary.org/obo/GO_0009583 CHEBI:62732 biolink:ChemicalSubstance aromatic ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_62732 GO:0009584 biolink:BiologicalProcess detection of visible light The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. go-plus.json perception of visible light http://purl.obolibrary.org/obo/GO_0009584 GO:0010573 biolink:BiologicalProcess vascular endothelial growth factor production The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json VEGF production http://purl.obolibrary.org/obo/GO_0010573 CHEBI:62733 biolink:ChemicalSubstance aromatic amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_62733 GO:0010570 biolink:BiologicalProcess regulation of filamentous growth Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0010570 GO:0009585 biolink:BiologicalProcess red, far-red light phototransduction The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm. go-plus.json phytochrome signaling pathway|red-sensitive opsin http://purl.obolibrary.org/obo/GO_0009585 GO:0034520 biolink:MolecularActivity 2-naphthaldehyde dehydrogenase activity Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+. EC:1.2.1.-|UM-BBD_reactionID:r0772 go-plus.json http://purl.obolibrary.org/obo/GO_0034520 GO:0010571 biolink:BiologicalProcess positive regulation of nuclear cell cycle DNA replication Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. go-plus.json positive regulation of DNA replication during S phase|positive regulation of DNA replication involved in S-phase|positive regulation of DNA replication involved in S phase http://purl.obolibrary.org/obo/GO_0010571 CHEBI:62731 biolink:ChemicalSubstance 2-methoxy-6-(all-trans-polyprenyl)phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62731 chebi_ph7_3 GO:0009586 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009586 GO:0009587 biolink:BiologicalProcess obsolete phototrophin mediated phototransduction OBSOLETE. (Was not defined before being made obsolete). go-plus.json phototrophin mediated phototransduction http://purl.obolibrary.org/obo/GO_0009587 GO:0034521 biolink:MolecularActivity 1-naphthoic acid dioxygenase activity Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+. EC:1.14.12.-|UM-BBD_reactionID:r0773 go-plus.json http://purl.obolibrary.org/obo/GO_0034521 GO:0010576 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010576 CHEBI:62736 biolink:ChemicalSubstance 4,4'-diapophytoene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62736 chebi_ph7_3 GO:0009588 biolink:BiologicalProcess UV-A, blue light phototransduction The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm. go-plus.json violet-sensitive opsin|blue-sensitive opsin|short-wave-sensitive opsin http://purl.obolibrary.org/obo/GO_0009588 GO:0034522 biolink:MolecularActivity cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-. UM-BBD_reactionID:r0774 go-plus.json http://purl.obolibrary.org/obo/GO_0034522 GO:0010577 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010577 GO:0010574 biolink:BiologicalProcess regulation of vascular endothelial growth factor production Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_0010574 GO:0034523 biolink:MolecularActivity 3-formylsalicylate oxidase activity Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide. UM-BBD_reactionID:r0777 go-plus.json http://purl.obolibrary.org/obo/GO_0034523 GO:0009589 biolink:BiologicalProcess detection of UV The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. go-plus.json detection of UV light stimulus|detection of UV radiation stimulus|perception of UV|detection of ultraviolet light stimulus|detection of ultraviolet radiation stimulus http://purl.obolibrary.org/obo/GO_0009589 CHEBI:62734 biolink:ChemicalSubstance 2,7-dihydroxy-4'-methoxyisoflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_62734 chebi_ph7_3 GO:0010575 biolink:BiologicalProcess positive regulation of vascular endothelial growth factor production Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_0010575 GO:0034524 biolink:MolecularActivity 2-hydroxyisophthalate decarboxylase activity Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2. UM-BBD_reactionID:r0776 go-plus.json http://purl.obolibrary.org/obo/GO_0034524 CHEBI:62735 biolink:ChemicalSubstance lupan-3beta,20-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62735 chebi_ph7_3 CHEBI:62738 biolink:ChemicalSubstance 15-cis-4,4'-diapophytoene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62738 chebi_ph7_3 CHEBI:62739 biolink:ChemicalSubstance 4,4'-diapophytofluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62739 chebi_ph7_3 CHEBI:23178 biolink:ChemicalSubstance cholest-7-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23178 chebi_ph7_3 GO:0010547 biolink:BiologicalProcess thylakoid membrane disassembly The controlled breakdown of the thylakoid membrane in the context of a normal process. go-plus.json thylakoid membrane degradation http://purl.obolibrary.org/obo/GO_0010547 GO:0034514 biolink:BiologicalProcess mitochondrial unfolded protein response The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins. go-plus.json mtUPR http://purl.obolibrary.org/obo/GO_0034514 GO:0034515 biolink:CellularComponent proteasome storage granule An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state. go-plus.json PSG http://purl.obolibrary.org/obo/GO_0034515 GO:0010548 biolink:BiologicalProcess regulation of thylakoid membrane disassembly Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly. go-plus.json regulation of thylakoid membrane degradation http://purl.obolibrary.org/obo/GO_0010548 GO:0034516 biolink:BiologicalProcess response to vitamin B6 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0034516 GO:0010545 biolink:MolecularActivity obsolete Hsp90 protein regulator activity OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsp90. go-plus.json Hsp90 protein regulator activity http://purl.obolibrary.org/obo/GO_0010545 GO:0010546 biolink:MolecularActivity obsolete Hsp90 protein inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the Hsp90 molecular chaperone. go-plus.json Hsp90 protein inhibitor activity http://purl.obolibrary.org/obo/GO_0010546 GO:0034517 biolink:BiologicalProcess ribophagy The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0034517 GO:0034518 biolink:CellularComponent RNA cap binding complex Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0034518 GO:0034519 biolink:CellularComponent cytoplasmic RNA cap binding complex A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0034519 CHEBI:62740 biolink:ChemicalSubstance all-trans-4,4'-diapophytofluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62740 chebi_ph7_3 GO:0010549 biolink:BiologicalProcess regulation of membrane disassembly Any process that modulates the frequency, rate or extent of membrane disassembly. go-plus.json http://purl.obolibrary.org/obo/GO_0010549 GO:0009560 biolink:BiologicalProcess embryo sac egg cell differentiation The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana. go-plus.json female gamete generation|female gametophyte egg cell differentiation http://purl.obolibrary.org/obo/GO_0009560 CHEBI:62743 biolink:ChemicalSubstance 4,4'-diaponeurosporene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62743 chebi_ph7_3 GO:0009550 biolink:CellularComponent primary plasmodesma A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis. go-plus.json simple plasmodesma http://purl.obolibrary.org/obo/GO_0009550 GO:0009551 biolink:CellularComponent secondary plasmodesma A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata. go-plus.json http://purl.obolibrary.org/obo/GO_0009551 GO:0010540 biolink:BiologicalProcess basipetal auxin transport The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root. go-plus.json http://purl.obolibrary.org/obo/GO_0010540 GO:0009552 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009552 CHEBI:62741 biolink:ChemicalSubstance 4,4'-diapo-zeta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62741 chebi_ph7_3 GO:0009553 biolink:BiologicalProcess embryo sac development The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate. go-plus.json female gametophyte development http://purl.obolibrary.org/obo/GO_0009553 CHEBI:62742 biolink:ChemicalSubstance all-trans-4,4'-diapo-zeta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62742 chebi_ph7_3 GO:0009554 biolink:BiologicalProcess megasporogenesis The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus. go-plus.json megaspore development|meiosis of the megasporocyte|megaspore mother cell meiosis|meiotic division of the megasporocyte http://purl.obolibrary.org/obo/GO_0009554 GO:0034510 biolink:BiologicalProcess centromere separation The cell cycle process in which centromeres are physically detached from each other during chromosome separation. go-plus.json http://purl.obolibrary.org/obo/GO_0034510 GO:0010543 biolink:BiologicalProcess regulation of platelet activation Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0010543 CHEBI:62747 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62747 GO:0009555 biolink:BiologicalProcess pollen development The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates. go-plus.json male gametophyte development|male gametophyte formation|microgametophyte development|formation of generative and vegetative cells|pollen grain formation http://purl.obolibrary.org/obo/GO_0009555 GO:0034511 biolink:MolecularActivity U3 snoRNA binding Binding to a U3 small nucleolar RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0034511 GO:0010544 biolink:BiologicalProcess negative regulation of platelet activation Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0010544 GO:0009556 biolink:BiologicalProcess microsporogenesis The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores. go-plus.json microspore development http://purl.obolibrary.org/obo/GO_0009556 GO:0034512 biolink:MolecularActivity box C/D RNA binding Binding to a box C/D small nucleolar RNA. go-plus.json box C/D sRNA binding|box C/D snoRNA binding http://purl.obolibrary.org/obo/GO_0034512 CHEBI:62745 biolink:ChemicalSubstance ammoniodiacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_62745 chebi_ph7_3 GO:0010541 biolink:BiologicalProcess acropetal auxin transport The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root. go-plus.json http://purl.obolibrary.org/obo/GO_0010541 GO:0009557 biolink:BiologicalProcess antipodal cell differentiation The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0009557 GO:0010542 biolink:MolecularActivity nitrate efflux transmembrane transporter activity Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0010542 GO:0034513 biolink:MolecularActivity box H/ACA snoRNA binding Binding to a box H/ACA small nucleolar RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0034513 CHEBI:62746 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62746 GO:0009558 biolink:BiologicalProcess embryo sac cellularization The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana. go-plus.json megagametophyte cellularization|female gametophyte cellularization|cellularization of the embryo sac http://purl.obolibrary.org/obo/GO_0009558 GO:0009559 biolink:BiologicalProcess embryo sac central cell differentiation The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell. go-plus.json female gametophyte central cell differentiation|embryo sac endosperm mother cell differentiation http://purl.obolibrary.org/obo/GO_0009559 CHEBI:62749 biolink:ChemicalSubstance 2-acylglycerophosphoinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_62749 CHEBI:47136 biolink:ChemicalSubstance pentachlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_47136 chebi_ph7_3 GO:0010558 biolink:BiologicalProcess negative regulation of macromolecule biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json http://purl.obolibrary.org/obo/GO_0010558 GO:0034503 biolink:BiologicalProcess protein localization to nucleolar rDNA repeats Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus. go-plus.json protein localisation to nucleolar rDNA repeats|condensin localization to nucleolar rDNA repeats http://purl.obolibrary.org/obo/GO_0034503 GO:0034504 biolink:BiologicalProcess protein localization to nucleus A process in which a protein transports or maintains the localization of another protein to the nucleus. go-plus.json protein localization in cell nucleus|protein localization in nucleus|protein targeting to nucleus|protein localisation to nucleus http://purl.obolibrary.org/obo/GO_0034504 GO:0010559 biolink:BiologicalProcess regulation of glycoprotein biosynthetic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_0010559 GO:0010556 biolink:BiologicalProcess regulation of macromolecule biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json http://purl.obolibrary.org/obo/GO_0010556 GO:0034505 biolink:BiologicalProcess tooth mineralization The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. go-plus.json tooth calcification http://purl.obolibrary.org/obo/GO_0034505 GO:0010557 biolink:BiologicalProcess positive regulation of macromolecule biosynthetic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json http://purl.obolibrary.org/obo/GO_0010557 GO:0034506 biolink:CellularComponent chromosome, centromeric core domain The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it. go-plus.json chromosome, centromeric core region|chromosome, centric core region http://purl.obolibrary.org/obo/GO_0034506 GO:0034507 biolink:CellularComponent chromosome, centromeric outer repeat region The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it. go-plus.json chromosome, centric outer repeat region http://purl.obolibrary.org/obo/GO_0034507 GO:0034508 biolink:BiologicalProcess centromere complex assembly The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere. go-plus.json centromere assembly|chromosome, centromeric region assembly|centromere organization http://purl.obolibrary.org/obo/GO_0034508 GO:0009570 biolink:CellularComponent chloroplast stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0009570 GO:0034509 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034509 CHEBI:47133 biolink:ChemicalSubstance 5'-chloro-5'-deoxyadenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47133 chebi_ph7_3 GO:0009571 biolink:CellularComponent proplastid stroma The space enclosed by the double membrane of a proplastid. go-plus.json http://purl.obolibrary.org/obo/GO_0009571 GO:0010550 biolink:BiologicalProcess regulation of PSII associated light-harvesting complex II catabolic process Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II. go-plus.json regulation of LHCII degradation|regulation of LHCII catabolism http://purl.obolibrary.org/obo/GO_0010550 GO:0009561 biolink:BiologicalProcess megagametogenesis The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. Wikipedia:Megagametogenesis go-plus.json megagametophyte nucleus division|embryo sac development from the megaspore http://purl.obolibrary.org/obo/GO_0009561 CHEBI:62755 biolink:ChemicalSubstance alpha-bergamotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62755 chebi_ph7_3 GO:0009562 biolink:BiologicalProcess embryo sac nuclear migration The directed movement of an embryo sac nucleus to the pole or center of the cell. go-plus.json megagametophyte nucleus migration|female gametophyte nucleus migration|megagametophyte nuclear migration|female gametophyte nuclear migration|embryo sac nucleus migration http://purl.obolibrary.org/obo/GO_0009562 GO:0010551 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010551 GO:0009563 biolink:BiologicalProcess synergid differentiation The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell. go-plus.json synergid cell differentiation http://purl.obolibrary.org/obo/GO_0009563 CHEBI:62753 biolink:ChemicalSubstance alpha-longipinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62753 chebi_ph7_3 GO:0009564 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009564 GO:0010554 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010554 GO:0009565 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009565 GO:0009566 biolink:BiologicalProcess fertilization The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). Wikipedia:Fertilisation go-plus.json syngamy http://purl.obolibrary.org/obo/GO_0009566 GO:0010555 biolink:BiologicalProcess response to mannitol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus. go-plus.json response to mannitol stimulus http://purl.obolibrary.org/obo/GO_0010555 GO:0034500 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034500 CHEBI:62759 biolink:ChemicalSubstance beta-curcumene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62759 chebi_ph7_3 GO:0034501 biolink:BiologicalProcess protein localization to kinetochore Any process in which a protein is transported to, or maintained at, the kinetochore. go-plus.json protein localisation to kinetochore|condensin localization to kinetochore http://purl.obolibrary.org/obo/GO_0034501 GO:0010552 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010552 GO:0009567 biolink:BiologicalProcess double fertilization forming a zygote and endosperm Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana. go-plus.json double fertilization http://purl.obolibrary.org/obo/GO_0009567 CHEBI:62756 biolink:ChemicalSubstance (-)-exo-alpha-bergamotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_62756 chebi_ph7_3 GO:0009568 biolink:CellularComponent amyloplast starch grain Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. go-plus.json amyloplast starch granule http://purl.obolibrary.org/obo/GO_0009568 GO:0010553 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010553 GO:0034502 biolink:BiologicalProcess protein localization to chromosome Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. go-plus.json protein localisation to chromosome|condensin localization to chromosome http://purl.obolibrary.org/obo/GO_0034502 GO:0009569 biolink:CellularComponent chloroplast starch grain Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. go-plus.json chloroplast starch granule http://purl.obolibrary.org/obo/GO_0009569 NCBITaxon:2231382 biolink:OrganismalEntity NPAAA clade go-plus.json non-protein amino acid accumulating clade|Canavanine-accumulating clade http://purl.obolibrary.org/obo/NCBITaxon_2231382 CHEBI:1506 biolink:ChemicalSubstance 3-fumarylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1506 NCBITaxon:2231393 biolink:OrganismalEntity 50 kb inversion clade go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2231393 NCBITaxon:1902 biolink:OrganismalEntity Streptomyces coelicolor go-plus.json Cladothrix coelicolor|Actinomyces coelicolor|Streptothrix coelicolor|Streptomyces coelicolor subspecies coelicolor|Nocardia coelicolor http://purl.obolibrary.org/obo/NCBITaxon_1902 GO:0034495 biolink:CellularComponent protein storage vacuole lumen The volume enclosed by the protein storage vacuole membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034495 GO:0034496 biolink:BiologicalProcess multivesicular body membrane disassembly The controlled breakdown of the membranes of multivesicular bodies. go-plus.json MVB membrane disassembly http://purl.obolibrary.org/obo/GO_0034496 GO:0034497 biolink:BiologicalProcess protein localization to phagophore assembly site Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). go-plus.json protein localization to pre-autophagosomal structure|protein localization to PAS|protein localisation to phagophore assembly site http://purl.obolibrary.org/obo/GO_0034497 GO:0034498 biolink:BiologicalProcess early endosome to Golgi transport The directed movement of substances from early endosomes to the Golgi. go-plus.json PGE to Golgi transport|post-Golgi endosome to Golgi transport http://purl.obolibrary.org/obo/GO_0034498 GO:0034499 biolink:BiologicalProcess late endosome to Golgi transport The directed movement of substances from late endosomes to the Golgi. go-plus.json prevacuolar endosome to Golgi transport|PVE to Golgi transport http://purl.obolibrary.org/obo/GO_0034499 GO:0034490 biolink:BiologicalProcess basic amino acid transmembrane import into vacuole The directed movement of basic amino acids into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034490 GO:0034491 biolink:BiologicalProcess neutral amino acid transmembrane import into vacuole The directed movement of neutral amino acids into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034491 GO:0034492 biolink:CellularComponent hydrogenosome lumen The volume enclosed by the hydrogenosome membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034492 GO:0034493 biolink:CellularComponent melanosome lumen The volume enclosed by the melanosome membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034493 GO:0034494 biolink:CellularComponent microneme lumen The volume enclosed by the microneme membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034494 GO:0034484 biolink:BiologicalProcess raffinose catabolic process The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json raffinose catabolism|raffinose degradation|raffinose breakdown http://purl.obolibrary.org/obo/GO_0034484 GO:0034485 biolink:MolecularActivity phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate. MetaCyc:RXN-10036|Reactome:R-HSA-1675949|RHEA:25528 go-plus.json http://purl.obolibrary.org/obo/GO_0034485 GO:0034486 biolink:BiologicalProcess vacuolar transmembrane transport The process in which a solute is transported from one side of the vacuolar membrane to the other. go-plus.json vacuolar membrane transport http://purl.obolibrary.org/obo/GO_0034486 GO:0034487 biolink:BiologicalProcess vacuolar amino acid transmembrane transport The process in which an amino acid is transported from one side of the vacuolar membrane to the other. go-plus.json vacuolar amino acid membrane transport http://purl.obolibrary.org/obo/GO_0034487 GO:0034488 biolink:BiologicalProcess basic amino acid transmembrane export from vacuole The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034488 GO:0034489 biolink:BiologicalProcess neutral amino acid transmembrane export from vacuole The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034489 GO:0034480 biolink:MolecularActivity phosphatidylcholine phospholipase C activity Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate. EC:3.1.4.3|MetaCyc:PHOSPHOLIPASE-C-RXN|RHEA:10604 go-plus.json phospholipase C, acting on phosphatidylcholine|alpha-toxin|Clostridium oedematiens beta- and gamma-toxins activity|phosphatidylcholine cholinephosphohydrolase activity|Clostridium welchii alpha-toxin activity|heat-labile hemolysin|lipophosphodiesterase I activity http://purl.obolibrary.org/obo/GO_0034480 GO:0034481 biolink:MolecularActivity chondroitin sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0034481 GO:0034482 biolink:MolecularActivity chondroitin 2-O-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues. go-plus.json chondroitin 2-O-sulphotransferase activity|chondroitin 2-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0034482 GO:0034483 biolink:MolecularActivity heparan sulfate sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0034483 CHEBI:1549 biolink:ChemicalSubstance 3-hydroxymonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1549 GO:0034473 biolink:BiologicalProcess U1 snRNA 3'-end processing Any process involved in forming the mature 3' end of a U1 snRNA molecule. go-plus.json U1 snRNA 3' end processing http://purl.obolibrary.org/obo/GO_0034473 GO:0034474 biolink:BiologicalProcess U2 snRNA 3'-end processing Any process involved in forming the mature 3' end of a U2 snRNA molecule. go-plus.json U2 snRNA 3' end processing http://purl.obolibrary.org/obo/GO_0034474 GO:0034475 biolink:BiologicalProcess U4 snRNA 3'-end processing Any process involved in forming the mature 3' end of a U4 snRNA molecule. go-plus.json U4 snRNA 3' end processing http://purl.obolibrary.org/obo/GO_0034475 GO:0034476 biolink:BiologicalProcess U5 snRNA 3'-end processing Any process involved in forming the mature 3' end of a U5 snRNA molecule. go-plus.json U5 snRNA 3' end processing http://purl.obolibrary.org/obo/GO_0034476 GO:0034477 biolink:BiologicalProcess U6 snRNA 3'-end processing Any process involved in forming the mature 3' end of a U6 snRNA molecule. go-plus.json U6 snRNA 3' end processing http://purl.obolibrary.org/obo/GO_0034477 GO:0034478 biolink:BiologicalProcess phosphatidylglycerol catabolic process The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. go-plus.json phosphatidylglycerol degradation|phosphatidylglycerol breakdown|phosphatidylglycerol catabolism http://purl.obolibrary.org/obo/GO_0034478 GO:0034479 biolink:MolecularActivity phosphatidylglycerol phospholipase C activity Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0034479 CHEBI:1547 biolink:ChemicalSubstance 3-hydroxykynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_1547 GO:0034470 biolink:BiologicalProcess ncRNA processing Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0034470 GO:0034471 biolink:BiologicalProcess ncRNA 5'-end processing Any process involved in forming the mature 5' end of a non-coding RNA molecule. go-plus.json ncRNA 5' end processing http://purl.obolibrary.org/obo/GO_0034471 GO:0034472 biolink:BiologicalProcess snRNA 3'-end processing Any process involved in forming the mature 3' end of an snRNA molecule. go-plus.json snRNA 3' end processing http://purl.obolibrary.org/obo/GO_0034472 GO:0034462 biolink:BiologicalProcess small-subunit processome assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome. go-plus.json SSU processome assembly|small subunit processome assembly http://purl.obolibrary.org/obo/GO_0034462 GO:0034463 biolink:BiologicalProcess 90S preribosome assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions. go-plus.json http://purl.obolibrary.org/obo/GO_0034463 GO:0034464 biolink:CellularComponent BBSome A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B. go-plus.json Bardet-Biedl syndrome complex http://purl.obolibrary.org/obo/GO_0034464 GO:0034465 biolink:BiologicalProcess response to carbon monoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0034465 GO:0034466 biolink:CellularComponent chromaffin granule lumen The volume enclosed by the membrane of a chromaffin granule. go-plus.json http://purl.obolibrary.org/obo/GO_0034466 GO:0034467 biolink:CellularComponent esterosome lumen The volume enclosed by the membrane of an esterosome. go-plus.json http://purl.obolibrary.org/obo/GO_0034467 GO:0034468 biolink:CellularComponent glycosome lumen The volume enclosed by the membrane of a glycosome. go-plus.json http://purl.obolibrary.org/obo/GO_0034468 GO:0034469 biolink:CellularComponent Golgi stack lumen The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034469 GO:0034460 biolink:BiologicalProcess uropod assembly The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane. go-plus.json uropod formation http://purl.obolibrary.org/obo/GO_0034460 GO:0034461 biolink:BiologicalProcess uropod retraction The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell. go-plus.json http://purl.obolibrary.org/obo/GO_0034461 GO:1902939 biolink:BiologicalProcess negative regulation of intracellular calcium activated chloride channel activity Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity. go-plus.json downregulation of intracellular calcium activated chloride channel activity|down-regulation of intracellular calcium activated chloride channel activity|inhibition of intracellular calcium activated chloride channel activity|down regulation of intracellular calcium activated chloride channel activity http://purl.obolibrary.org/obo/GO_1902939 GO:1902937 biolink:CellularComponent inward rectifier potassium channel complex A protein complex which is capable of inward rectifier potassium channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902937 GO:1902938 biolink:BiologicalProcess regulation of intracellular calcium activated chloride channel activity Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_1902938 GO:1902935 biolink:BiologicalProcess protein localization to septin ring A process in which a protein is transported to, or maintained in, a location within a septin ring. go-plus.json protein localisation to septin ring|protein localization in septin ring|protein localisation in septin ring http://purl.obolibrary.org/obo/GO_1902935 GO:1902936 biolink:MolecularActivity phosphatidylinositol bisphosphate binding Binding to phosphatidylinositol bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1902936 GO:1902933 biolink:BiologicalProcess isopentenol metabolic process The chemical reactions and pathways involving isopentenol. go-plus.json isopentenol metabolism http://purl.obolibrary.org/obo/GO_1902933 GO:1902934 biolink:BiologicalProcess isopentenol biosynthetic process The chemical reactions and pathways resulting in the formation of isopentenol. go-plus.json isopentenol synthesis|isopentenol formation|isopentenol biosynthesis|isopentenol anabolism http://purl.obolibrary.org/obo/GO_1902934 GO:1902931 biolink:BiologicalProcess negative regulation of alcohol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process. go-plus.json down regulation of alcohol anabolism|downregulation of alcohol biosynthesis|downregulation of alcohol biosynthetic process|down regulation of alcohol synthesis|downregulation of alcohol anabolism|down regulation of alcohol biosynthesis|down regulation of alcohol biosynthetic process|down regulation of alcohol formation|inhibition of alcohol biosynthesis|inhibition of alcohol biosynthetic process|downregulation of alcohol synthesis|downregulation of alcohol formation|down-regulation of alcohol anabolism|negative regulation of alcohol anabolism|negative regulation of solventogenesis|down-regulation of alcohol synthesis|negative regulation of alcohol synthesis|down-regulation of alcohol formation|negative regulation of alcohol formation|inhibition of alcohol anabolism|inhibition of alcohol synthesis|down-regulation of alcohol biosynthesis|down-regulation of alcohol biosynthetic process|negative regulation of alcohol biosynthesis|inhibition of alcohol formation http://purl.obolibrary.org/obo/GO_1902931 GO:1902932 biolink:BiologicalProcess positive regulation of alcohol biosynthetic process Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process. go-plus.json positive regulation of alcohol biosynthesis|upregulation of alcohol anabolism|up regulation of alcohol biosynthesis|up regulation of alcohol biosynthetic process|upregulation of alcohol synthesis|upregulation of alcohol formation|up regulation of alcohol anabolism|upregulation of alcohol biosynthesis|upregulation of alcohol biosynthetic process|activation of alcohol anabolism|positive regulation of alcohol anabolism|up regulation of alcohol synthesis|activation of alcohol synthesis|positive regulation of solventogenesis|positive regulation of alcohol synthesis|up regulation of alcohol formation|activation of alcohol formation|positive regulation of alcohol formation|up-regulation of alcohol biosynthesis|up-regulation of alcohol biosynthetic process|activation of alcohol biosynthesis|activation of alcohol biosynthetic process|up-regulation of alcohol anabolism|up-regulation of alcohol synthesis|up-regulation of alcohol formation http://purl.obolibrary.org/obo/GO_1902932 GO:1902930 biolink:BiologicalProcess regulation of alcohol biosynthetic process Any process that modulates the frequency, rate or extent of alcohol biosynthetic process. go-plus.json regulation of alcohol anabolism|regulation of alcohol biosynthesis|regulation of solventogenesis|regulation of alcohol synthesis|regulation of alcohol formation http://purl.obolibrary.org/obo/GO_1902930 CHEBI:37712 biolink:ChemicalSubstance O-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37712 CHEBI:37713 biolink:ChemicalSubstance O-phospho-D-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_37713 CHEBI:72058 biolink:ChemicalSubstance phosphatidylserine 34:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72058 chebi_ph7_3 CHEBI:72059 biolink:ChemicalSubstance phosphatidylserine 34:2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72059 chebi_ph7_3 GO:1902948 biolink:BiologicalProcess negative regulation of tau-protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity. go-plus.json negative regulation of TPK II|down-regulation of TPK II|down regulation of tau-protein kinase II activity|down regulation of GSK|inhibition of TPK I|down regulation of [Tau protein] kinase activity|down-regulation of tau-protein kinase I activity|negative regulation of tau-protein kinase I activity|down-regulation of TTK|downregulation of glycogen synthase kinase-3beta activity|negative regulation of TTK|down regulation of tau protein kinase activity|down-regulation of CDK5/p23|negative regulation of CDK5/p23|down regulation of protein tau kinase activity|negative regulation of STK31|down-regulation of STK31|inhibition of tau-protein kinase activity|negative regulation of brain protein kinase PK40erk activity|down-regulation of brain protein kinase PK40erk activity|downregulation of GSK|downregulation of [Tau protein] kinase activity|inhibition of tau-protein kinase II activity|down regulation of tau kinase activity|down-regulation of cdk5/p20|negative regulation of cdk5/p20|downregulation of protein tau kinase activity|down regulation of TPK I|downregulation of tau protein kinase activity|downregulation of TPK II|inhibition of TPK|downregulation of tau kinase activity|down-regulation of glycogen synthase kinase-3beta activity|negative regulation of glycogen synthase kinase-3beta activity|inhibition of tau-tubulin kinase activity|downregulation of TPK I|down regulation of TPK II|downregulation of CDK5/p23|inhibition of tau-protein kinase I activity|down-regulation of GSK|negative regulation of GSK|inhibition of TTK|negative regulation of [Tau protein] kinase activity|down-regulation of [Tau protein] kinase activity|downregulation of cdk5/p20|down regulation of tau-protein kinase activity|inhibition of STK31|down-regulation of protein tau kinase activity|inhibition of brain protein kinase PK40erk activity|negative regulation of protein tau kinase activity|down-regulation of tau protein kinase activity|negative regulation of tau protein kinase activity|down regulation of TPK|down regulation of CDK5/p23|inhibition of glycogen synthase kinase-3beta activity|down regulation of tau-tubulin kinase activity|negative regulation of tau-protein kinase II activity|down-regulation of tau-protein kinase II activity|inhibition of TPK II|down regulation of cdk5/p20|negative regulation of tau kinase activity|down-regulation of tau kinase activity|down-regulation of TPK I|down regulation of TTK|negative regulation of TPK I|down regulation of tau-protein kinase I activity|downregulation of TPK|downregulation of tau-protein kinase activity|downregulation of tau-tubulin kinase activity|inhibition of [Tau protein] kinase activity|inhibition of tau protein kinase activity|inhibition of CDK5/p23|down regulation of STK31|down regulation of brain protein kinase PK40erk activity|inhibition of protein tau kinase activity|downregulation of tau-protein kinase I activity|downregulation of TTK|inhibition of GSK|inhibition of tau kinase activity|inhibition of cdk5/p20|downregulation of tau-protein kinase II activity|downregulation of brain protein kinase PK40erk activity|downregulation of STK31|down regulation of glycogen synthase kinase-3beta activity|down-regulation of tau-protein kinase activity|down-regulation of TPK|negative regulation of TPK|negative regulation of tau-tubulin kinase activity|down-regulation of tau-tubulin kinase activity http://purl.obolibrary.org/obo/GO_1902948 GO:1902949 biolink:BiologicalProcess positive regulation of tau-protein kinase activity Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity. go-plus.json upregulation of [Tau protein] kinase activity|up regulation of STK31|activation of TPK|activation of TPK II|activation of tau-tubulin kinase activity|up-regulation of cdk5/p20|positive regulation of brain protein kinase PK40erk activity|positive regulation of STK31|upregulation of protein tau kinase activity|upregulation of tau protein kinase activity|upregulation of tau-protein kinase II activity|activation of tau-protein kinase I activity|activation of CDK5/p23|activation of TTK|upregulation of tau kinase activity|positive regulation of TPK II|up-regulation of tau-protein kinase activity|up-regulation of tau-tubulin kinase activity|up regulation of glycogen synthase kinase-3beta activity|up-regulation of TPK|upregulation of TPK I|activation of brain protein kinase PK40erk activity|activation of cdk5/p20|up regulation of TPK II|activation of glycogen synthase kinase-3beta activity|activation of STK31|positive regulation of glycogen synthase kinase-3beta activity|up regulation of GSK|up-regulation of tau-protein kinase I activity|positive regulation of CDK5/p23|up regulation of [Tau protein] kinase activity|up-regulation of TTK|up regulation of CDK5/p23|activation of [Tau protein] kinase activity|positive regulation of GSK|up-regulation of brain protein kinase PK40erk activity|up regulation of tau protein kinase activity|up regulation of protein tau kinase activity|positive regulation of cdk5/p20|positive regulation of [Tau protein] kinase activity|up-regulation of tau-protein kinase II activity|activation of tau protein kinase activity|up-regulation of STK31|activation of protein tau kinase activity|positive regulation of protein tau kinase activity|positive regulation of tau protein kinase activity|up regulation of cdk5/p20|upregulation of tau-tubulin kinase activity|upregulation of tau-protein kinase activity|up regulation of tau kinase activity|upregulation of TPK|up regulation of TPK I|activation of tau kinase activity|activation of GSK|upregulation of TPK II|positive regulation of tau kinase activity|positive regulation of TPK I|upregulation of tau-protein kinase I activity|activation of tau-protein kinase II activity|upregulation of TTK|up-regulation of glycogen synthase kinase-3beta activity|upregulation of CDK5/p23|upregulation of brain protein kinase PK40erk activity|upregulation of STK31|up-regulation of GSK|up-regulation of [Tau protein] kinase activity|positive regulation of tau-protein kinase II activity|activation of TPK I|upregulation of cdk5/p20|up regulation of tau-protein kinase II activity|up-regulation of tau protein kinase activity|up regulation of TPK|up-regulation of protein tau kinase activity|up regulation of tau-tubulin kinase activity|up regulation of tau-protein kinase activity|activation of tau-protein kinase activity|up-regulation of TPK II|positive regulation of TPK|positive regulation of tau-tubulin kinase activity|upregulation of glycogen synthase kinase-3beta activity|up-regulation of tau kinase activity|up regulation of tau-protein kinase I activity|up regulation of TTK|up-regulation of TPK I|positive regulation of tau-protein kinase I activity|up-regulation of CDK5/p23|upregulation of GSK|up regulation of brain protein kinase PK40erk activity|positive regulation of TTK http://purl.obolibrary.org/obo/GO_1902949 GO:1902946 biolink:BiologicalProcess protein localization to early endosome A process in which a protein is transported to, or maintained in, a location within an early endosome. go-plus.json protein localisation to early endosome|protein localisation in early endosome|protein localization in early endosome http://purl.obolibrary.org/obo/GO_1902946 GO:1902947 biolink:BiologicalProcess regulation of tau-protein kinase activity Any process that modulates the frequency, rate or extent of tau-protein kinase activity. go-plus.json regulation of glycogen synthase kinase-3beta activity|regulation of GSK|regulation of ATP:tau-protein O-phosphotransferase activity|regulation of [Tau protein] kinase activity|regulation of protein tau kinase activity|regulation of tau protein kinase activity|regulation of tau kinase activity|regulation of TPK I|regulation of TPK II|regulation of CDK5/p23|regulation of cdk5/p20|regulation of TPK|regulation of tau-tubulin kinase activity|regulation of tau-protein kinase I activity|regulation of TTK|regulation of brain protein kinase PK40erk activity|regulation of STK31|regulation of tau-protein kinase II activity http://purl.obolibrary.org/obo/GO_1902947 GO:1902944 biolink:MolecularActivity aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process. go-plus.json aspartate protease activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|carboxyl protease activity involved in APP catabolic process|aspartic endopeptidase activity involved in amyloid precursor protein catabolism|aspartic protease activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in APP catabolism|aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in amyloid precursor protein degradation|aspartic endopeptidase activity involved in APP catabolic process|aspartic protease activity involved in amyloid precursor protein catabolic process|aspartyl protease activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in amyloid precursor protein catabolism|aspartic protease activity involved in APP catabolism|aspartic protease activity involved in APP catabolic process|aspartyl protease activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein degradation|aspartic protease activity involved in amyloid precursor protein catabolism|aspartic-type endopeptidase activity involved in APP catabolism|carboxyl protease activity involved in amyloid precursor protein degradation|aspartyl protease activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein breakdown|carboxyl protease activity involved in APP catabolism|aspartic endopeptidase activity involved in amyloid precursor protein degradation|carboxyl protease activity involved in amyloid precursor protein breakdown|aspartate protease activity involved in amyloid precursor protein catabolic process|aspartate protease activity involved in APP catabolism|aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|carboxyl protease activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in APP catabolism|carboxyl protease activity involved in amyloid precursor protein catabolic process|aspartic endopeptidase activity involved in amyloid precursor protein breakdown|aspartic protease activity involved in amyloid precursor protein degradation http://purl.obolibrary.org/obo/GO_1902944 GO:1902945 biolink:MolecularActivity metalloendopeptidase activity involved in amyloid precursor protein catabolic process Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process. Reactome:R-HSA-9010034 go-plus.json metalloendoproteinase activity involved in amyloid precursor protein catabolic process|metalloendoprotease activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein catabolic process|metalloendoproteinase activity involved in APP catabolic process|metalloendopeptidase activity involved in APP catabolism|metalloendoprotease activity involved in APP catabolic process|metalloendopeptidase activity involved in amyloid precursor protein catabolism|metalloendoprotease activity involved in APP catabolism|metalloendopeptidase activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in APP catabolism|metalloendopeptidase activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein catabolism|metalloendoproteinase activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in amyloid precursor protein catabolism|metalloendoproteinase activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein degradation|metalloendopeptidase activity involved in APP catabolic process http://purl.obolibrary.org/obo/GO_1902945 GO:1902942 biolink:BiologicalProcess negative regulation of voltage-gated chloride channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity. go-plus.json downregulation of voltage-dependent chloride channel activity|down-regulation of voltage gated chloride channel activity|down regulation of voltage-gated chloride channel activity|negative regulation of voltage gated chloride channel activity|downregulation of voltage-gated chloride channel activity|inhibition of voltage gated chloride channel activity|negative regulation of voltage-dependent chloride channel activity|down-regulation of voltage-dependent chloride channel activity|inhibition of voltage-dependent chloride channel activity|down-regulation of voltage-gated chloride channel activity|down regulation of voltage gated chloride channel activity|inhibition of voltage-gated chloride channel activity|downregulation of voltage gated chloride channel activity|down regulation of voltage-dependent chloride channel activity http://purl.obolibrary.org/obo/GO_1902942 GO:1902943 biolink:BiologicalProcess positive regulation of voltage-gated chloride channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity. go-plus.json upregulation of voltage-gated chloride channel activity|up regulation of voltage-dependent chloride channel activity|activation of voltage-dependent chloride channel activity|positive regulation of voltage-dependent chloride channel activity|up-regulation of voltage gated chloride channel activity|up regulation of voltage-gated chloride channel activity|activation of voltage-gated chloride channel activity|up-regulation of voltage-dependent chloride channel activity|upregulation of voltage gated chloride channel activity|up-regulation of voltage-gated chloride channel activity|upregulation of voltage-dependent chloride channel activity|up regulation of voltage gated chloride channel activity|activation of voltage gated chloride channel activity|positive regulation of voltage gated chloride channel activity http://purl.obolibrary.org/obo/GO_1902943 GO:1902940 biolink:BiologicalProcess positive regulation of intracellular calcium activated chloride channel activity Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity. go-plus.json upregulation of intracellular calcium activated chloride channel activity|up regulation of intracellular calcium activated chloride channel activity|activation of intracellular calcium activated chloride channel activity|up-regulation of intracellular calcium activated chloride channel activity http://purl.obolibrary.org/obo/GO_1902940 GO:1902941 biolink:BiologicalProcess regulation of voltage-gated chloride channel activity Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity. go-plus.json regulation of voltage gated chloride channel activity|regulation of voltage-dependent chloride channel activity http://purl.obolibrary.org/obo/GO_1902941 CHEBI:37721 biolink:ChemicalSubstance D-fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37721 chebi_ph7_3 CHEBI:37722 biolink:ChemicalSubstance fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37722 CHEBI:37725 biolink:ChemicalSubstance L-fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37725 chebi_ph7_3 CHEBI:37723 biolink:ChemicalSubstance keto-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37723 CHEBI:37724 biolink:ChemicalSubstance keto-L-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37724 chebi_ph7_3 GO:1902959 biolink:BiologicalProcess regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. go-plus.json regulation of carboxyl protease activity involved in APP catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|regulation of aspartic protease activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|regulation of aspartate protease activity involved in amyloid precursor protein catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|regulation of carboxyl protease activity involved in APP catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein breakdown|regulation of aspartyl protease activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in APP catabolic process|regulation of aspartic endopeptidase activity involved in APP catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic-type endopeptidase activity involved in APP catabolic process|regulation of aspartyl protease activity involved in APP catabolism|regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartic protease activity involved in APP catabolic process|regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|regulation of aspartic protease activity involved in APP catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein degradation|regulation of aspartyl protease activity involved in APP catabolic process|regulation of aspartic-type endopeptidase activity involved in APP catabolism|regulation of aspartate protease activity involved in amyloid precursor protein degradation|regulation of aspartic protease activity involved in amyloid precursor protein catabolism|regulation of aspartic endopeptidase activity involved in APP catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in APP catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartate protease activity involved in amyloid precursor protein breakdown|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation http://purl.obolibrary.org/obo/GO_1902959 GO:1902957 biolink:BiologicalProcess negative regulation of mitochondrial electron transport, NADH to ubiquinone Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. go-plus.json inhibition of oxidative phosphorylation, NADH to ubiquinone|down regulation of complex I (NADH to ubiquinone)|inhibition of complex I (NADH to ubiquinone)|down-regulation of mitochondrial electron transport, NADH to ubiquinone|down regulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of mitochondrial electron transport, NADH to ubiquinone|negative regulation of complex I (NADH to ubiquinone)|down-regulation of complex I (NADH to ubiquinone)|down regulation of mitochondrial electron transport, NADH to ubiquinone|inhibition of mitochondrial electron transport, NADH to ubiquinone|down-regulation of oxidative phosphorylation, NADH to ubiquinone|negative regulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of complex I (NADH to ubiquinone) http://purl.obolibrary.org/obo/GO_1902957 GO:1902958 biolink:BiologicalProcess positive regulation of mitochondrial electron transport, NADH to ubiquinone Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. go-plus.json up-regulation of oxidative phosphorylation, NADH to ubiquinone|up-regulation of mitochondrial electron transport, NADH to ubiquinone|activation of mitochondrial electron transport, NADH to ubiquinone|upregulation of complex I (NADH to ubiquinone)|upregulation of oxidative phosphorylation, NADH to ubiquinone|up-regulation of complex I (NADH to ubiquinone)|up regulation of mitochondrial electron transport, NADH to ubiquinone|activation of complex I (NADH to ubiquinone)|up regulation of oxidative phosphorylation, NADH to ubiquinone|positive regulation of oxidative phosphorylation, NADH to ubiquinone|activation of oxidative phosphorylation, NADH to ubiquinone|positive regulation of complex I (NADH to ubiquinone)|upregulation of mitochondrial electron transport, NADH to ubiquinone|up regulation of complex I (NADH to ubiquinone) http://purl.obolibrary.org/obo/GO_1902958 GO:1902955 biolink:BiologicalProcess positive regulation of early endosome to recycling endosome transport Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport. go-plus.json up-regulation of early endosome to recycling endosome transport|activation of early endosome to recycling endosome transport|up regulation of early endosome to recycling endosome transport|upregulation of early endosome to recycling endosome transport http://purl.obolibrary.org/obo/GO_1902955 GO:1902956 biolink:BiologicalProcess regulation of mitochondrial electron transport, NADH to ubiquinone Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. go-plus.json regulation of oxidative phosphorylation, NADH to ubiquinone|regulation of complex I (NADH to ubiquinone) http://purl.obolibrary.org/obo/GO_1902956 GO:1902953 biolink:BiologicalProcess positive regulation of ER to Golgi vesicle-mediated transport Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport. go-plus.json positive regulation of endoplasmic reticulum to Golgi transport|up regulation of endoplasmic reticulum to Golgi transport|up regulation of ER to Golgi vesicle-mediated transport|up-regulation of rough ER to cis-Golgi transport|up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|upregulation of rough endoplasmic reticulum to cis-Golgi transport|upregulation of rough ER to cis-Golgi vesicle-mediated transport|upregulation of ER to Golgi transport|upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport|upregulation of endoplasmic reticulum to Golgi transport|upregulation of ER to Golgi vesicle-mediated transport|upregulation of rough ER to cis-Golgi transport|upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|up-regulation of rough endoplasmic reticulum to cis-Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi transport|up-regulation of rough ER to cis-Golgi vesicle-mediated transport|activation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of ER to Golgi transport|up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|positive regulation of ER to Golgi transport|activation of ER to Golgi transport|positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|activation of endoplasmic reticulum to Golgi vesicle-mediated transport|up-regulation of endoplasmic reticulum to Golgi transport|activation of endoplasmic reticulum to Golgi transport|up-regulation of ER to Golgi vesicle-mediated transport|activation of ER to Golgi vesicle-mediated transport|up regulation of rough ER to cis-Golgi transport|up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi transport|positive regulation of rough endoplasmic reticulum to cis-Golgi transport|activation of rough ER to cis-Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of rough endoplasmic reticulum to cis-Golgi transport|up regulation of rough ER to cis-Golgi vesicle-mediated transport|up-regulation of ER to Golgi transport|up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport http://purl.obolibrary.org/obo/GO_1902953 GO:1902954 biolink:BiologicalProcess regulation of early endosome to recycling endosome transport Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport. go-plus.json http://purl.obolibrary.org/obo/GO_1902954 GO:1902951 biolink:BiologicalProcess negative regulation of dendritic spine maintenance Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance. go-plus.json inhibition of dendritic spine maintenance|down regulation of dendritic spine maintenance|downregulation of dendritic spine maintenance|down-regulation of dendritic spine maintenance http://purl.obolibrary.org/obo/GO_1902951 GO:1902952 biolink:BiologicalProcess positive regulation of dendritic spine maintenance Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance. go-plus.json up-regulation of dendritic spine maintenance|upregulation of dendritic spine maintenance|up regulation of dendritic spine maintenance|activation of dendritic spine maintenance http://purl.obolibrary.org/obo/GO_1902952 CHEBI:13769 biolink:ChemicalSubstance aminohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_13769 chebi_ph7_3 GO:1902950 biolink:BiologicalProcess regulation of dendritic spine maintenance Any process that modulates the frequency, rate or extent of dendritic spine maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_1902950 CHEBI:72065 biolink:ChemicalSubstance phosphatidylserine 36:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72065 chebi_ph7_3 CHEBI:72066 biolink:ChemicalSubstance phosphatidylserine 36:2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72066 chebi_ph7_3 CHEBI:72067 biolink:ChemicalSubstance phosphatidylserine 36:3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72067 chebi_ph7_3 CHEBI:72068 biolink:ChemicalSubstance phosphatidylserine 36:4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72068 chebi_ph7_3 GO:1902968 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1902968 GO:1902969 biolink:BiologicalProcess mitotic DNA replication Any nuclear DNA replication that is involved in a mitotic cell cycle. go-plus.json DNA replication involved in S phase involved in mitotic cell cycle|mitotic cell cycle DNA replication|DNA replication during S phase involved in mitotic cell cycle|mitotic nuclear cell cycle DNA replication|nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication involved in S-phase involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902969 GO:1902966 biolink:BiologicalProcess positive regulation of protein localization to early endosome Any process that activates or increases the frequency, rate or extent of protein localization to early endosome. go-plus.json activation of protein localization to early endosome|up-regulation of protein localization to early endosome|upregulation of protein localization in early endosome|activation of protein localisation in early endosome|up-regulation of protein localisation in early endosome|positive regulation of protein localisation to early endosome|up regulation of protein localisation to early endosome|up-regulation of protein localization in early endosome|activation of protein localization in early endosome|up regulation of protein localization to early endosome|positive regulation of protein localisation in early endosome|upregulation of protein localisation to early endosome|up regulation of protein localisation in early endosome|positive regulation of protein localization in early endosome|upregulation of protein localization to early endosome|up regulation of protein localization in early endosome|up-regulation of protein localisation to early endosome|activation of protein localisation to early endosome|upregulation of protein localisation in early endosome http://purl.obolibrary.org/obo/GO_1902966 GO:1902967 biolink:BiologicalProcess protein localization to mitotic spindle midzone A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone. go-plus.json protein localisation to mitotic spindle midzone|protein localization in mitotic spindle midzone|protein localisation in mitotic spindle midzone http://purl.obolibrary.org/obo/GO_1902967 GO:1902964 biolink:BiologicalProcess positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. go-plus.json up-regulation of metalloendopeptidase activity involved in APP catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|activation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in APP catabolic process|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoproteinase activity involved in APP catabolism|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in APP catabolic process|activation of metalloendoprotease activity involved in APP catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoprotease activity involved in APP catabolism|positive regulation of metalloendopeptidase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in APP catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|activation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up regulation of metalloendopeptidase activity involved in APP catabolism|positive regulation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoproteinase activity involved in APP catabolism|positive regulation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoproteinase activity involved in APP catabolism|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|upregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoproteinase activity involved in APP catabolism|activation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in APP catabolic process|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of metalloendoprotease activity involved in APP catabolic process|up regulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|activation of metalloendopeptidase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein degradation|upregulation of metalloendopeptidase activity involved in APP catabolism|positive regulation of metalloendopeptidase activity involved in APP catabolic process|up regulation of metalloendoprotease activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoprotease activity involved in APP catabolism|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|activation of metalloendoprotease activity involved in amyloid precursor protein degradation|activation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|upregulation of metalloendoproteinase activity involved in APP catabolic process|up-regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendopeptidase activity involved in APP catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in amyloid precursor protein breakdown|activation of metalloendopeptidase activity involved in APP catabolism|upregulation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|upregulation of metalloendoprotease activity involved in APP catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation http://purl.obolibrary.org/obo/GO_1902964 GO:1902965 biolink:BiologicalProcess regulation of protein localization to early endosome Any process that modulates the frequency, rate or extent of protein localization to early endosome. go-plus.json regulation of protein localisation to early endosome|regulation of protein localisation in early endosome|regulation of protein localization in early endosome http://purl.obolibrary.org/obo/GO_1902965 CHEBI:37708 biolink:ChemicalSubstance altrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_37708 GO:1902962 biolink:BiologicalProcess regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. go-plus.json regulation of metalloendoprotease activity involved in APP catabolism|regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|regulation of metalloendoproteinase activity involved in APP catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|regulation of metalloendopeptidase activity involved in APP catabolic process|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|regulation of metalloendopeptidase activity involved in APP catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|regulation of metalloendoproteinase activity involved in APP catabolic process|regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|regulation of metalloendoprotease activity involved in APP catabolic process|regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation http://purl.obolibrary.org/obo/GO_1902962 GO:1902963 biolink:BiologicalProcess negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. go-plus.json downregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in APP catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|down-regulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendoprotease activity involved in APP catabolism|downregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoproteinase activity involved in APP catabolism|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|downregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in APP catabolic process|inhibition of metalloendoproteinase activity involved in amyloid precursor protein degradation|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoproteinase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|downregulation of metalloendoproteinase activity involved in APP catabolism|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|down regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|downregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoprotease activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendoprotease activity involved in APP catabolism|down-regulation of metalloendoprotease activity involved in APP catabolism|downregulation of metalloendopeptidase activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein degradation|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendopeptidase activity involved in APP catabolism|down regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in APP catabolic process|down-regulation of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendoproteinase activity involved in APP catabolism|inhibition of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|inhibition of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|inhibition of metalloendoprotease activity involved in APP catabolism|inhibition of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoproteinase activity involved in APP catabolic process|downregulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|inhibition of metalloendoproteinase activity involved in APP catabolic process|negative regulation of metalloendopeptidase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in APP catabolism|down regulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|inhibition of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in APP catabolic process|down-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown http://purl.obolibrary.org/obo/GO_1902963 GO:1902960 biolink:BiologicalProcess negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. go-plus.json downregulation of aspartyl protease activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in APP catabolism|down-regulation of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic endopeptidase activity involved in APP catabolic process|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in APP catabolism|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic protease activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein degradation|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartyl protease activity involved in APP catabolism|downregulation of aspartic endopeptidase activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of aspartyl protease activity involved in APP catabolism|downregulation of aspartic-type endopeptidase activity involved in APP catabolism|downregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in APP catabolic process|inhibition of aspartate protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|downregulation of aspartate protease activity involved in APP catabolism|inhibition of aspartyl protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in APP catabolic process|negative regulation of carboxyl protease activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartic endopeptidase activity involved in APP catabolic process|down-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in amyloid precursor protein degradation|down regulation of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in APP catabolism|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|inhibition of aspartic endopeptidase activity involved in APP catabolism|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of carboxyl protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|inhibition of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in APP catabolism|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartyl protease activity involved in APP catabolism|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic protease activity involved in APP catabolism|negative regulation of aspartic protease activity involved in APP catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein degradation|inhibition of aspartate protease activity involved in APP catabolism|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in APP catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in amyloid precursor protein degradation|down-regulation of aspartate protease activity involved in amyloid precursor protein degradation|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in APP catabolic process|inhibition of aspartate protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in APP catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of aspartic protease activity involved in APP catabolic process|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in amyloid precursor protein degradation|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in APP catabolic process|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down regulation of carboxyl protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein breakdown|inhibition of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of aspartic endopeptidase activity involved in APP catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein breakdown|inhibition of aspartate protease activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartate protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in APP catabolism|negative regulation of carboxyl protease activity involved in APP catabolism|down regulation of aspartyl protease activity involved in APP catabolism|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of aspartic protease activity involved in amyloid precursor protein catabolism|inhibition of aspartyl protease activity involved in amyloid precursor protein degradation|down-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of carboxyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartic-type endopeptidase activity involved in APP catabolic process|down-regulation of aspartyl protease activity involved in APP catabolic process|negative regulation of aspartyl protease activity involved in APP catabolic process|down regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in APP catabolic process|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of aspartic endopeptidase activity involved in APP catabolism|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in APP catabolism|down regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in APP catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|inhibition of carboxyl protease activity involved in APP catabolism|inhibition of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in APP catabolism|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartate protease activity involved in APP catabolism|down regulation of aspartic protease activity involved in APP catabolic process|down regulation of aspartic protease activity involved in APP catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartate protease activity involved in APP catabolic process|negative regulation of aspartate protease activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolic process|downregulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process http://purl.obolibrary.org/obo/GO_1902960 GO:1902961 biolink:BiologicalProcess positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. go-plus.json up regulation of aspartic endopeptidase activity involved in APP catabolism|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic protease activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in APP catabolism|up-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartate protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up regulation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic protease activity involved in amyloid precursor protein degradation|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of aspartyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartate protease activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in APP catabolism|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|upregulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up regulation of aspartic protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in APP catabolic process|activation of aspartyl protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartic endopeptidase activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein catabolism|upregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|positive regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic-type endopeptidase activity involved in APP catabolism|up regulation of aspartate protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic protease activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|activation of aspartic-type endopeptidase activity involved in APP catabolism|upregulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartic protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in APP catabolism|activation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|activation of aspartate protease activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up regulation of carboxyl protease activity involved in APP catabolic process|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartate protease activity involved in APP catabolism|up regulation of aspartic protease activity involved in amyloid precursor protein breakdown|activation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein degradation|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartate protease activity involved in APP catabolic process|up regulation of aspartyl protease activity involved in amyloid precursor protein degradation|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of carboxyl protease activity involved in APP catabolism|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in APP catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartate protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartate protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic protease activity involved in APP catabolism|activation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|activation of aspartyl protease activity involved in APP catabolic process|positive regulation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in APP catabolism|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartic endopeptidase activity involved in APP catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic-type endopeptidase activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic-type endopeptidase activity involved in APP catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartate protease activity involved in amyloid precursor protein catabolic process|activation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in APP catabolism|activation of carboxyl protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of aspartic protease activity involved in APP catabolic process|activation of aspartate protease activity involved in APP catabolism|up-regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|activation of carboxyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|up regulation of aspartate protease activity involved in APP catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein degradation|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in APP catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein degradation|activation of aspartate protease activity involved in APP catabolic process|up regulation of aspartic endopeptidase activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in APP catabolic process|positive regulation of aspartyl protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartic endopeptidase activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in APP catabolism|activation of aspartic endopeptidase activity involved in APP catabolic process|activation of aspartate protease activity involved in amyloid precursor protein catabolism|up regulation of aspartyl protease activity involved in APP catabolism|up regulation of aspartyl protease activity involved in APP catabolic process|upregulation of aspartic-type endopeptidase activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartyl protease activity involved in APP catabolism|activation of carboxyl protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartate protease activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|activation of aspartyl protease activity involved in APP catabolism http://purl.obolibrary.org/obo/GO_1902961 CHEBI:13759 biolink:ChemicalSubstance alkylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_13759 CHEBI:37700 biolink:ChemicalSubstance EC 2.7.11.13 (protein kinase C) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_37700 CHEBI:13757 biolink:ChemicalSubstance n-alk-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_13757 chebi_ph7_3 CHEBI:37702 biolink:ChemicalSubstance aldonate ester phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_37702 CHEBI:72075 biolink:ChemicalSubstance phosphatidylserine 38:4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72075 chebi_ph7_3 CHEBI:72076 biolink:ChemicalSubstance phosphatidylserine 38:5(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72076 chebi_ph7_3 CHEBI:72077 biolink:ChemicalSubstance phosphatidylserine 38:6(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72077 chebi_ph7_3 CHEBI:589779 biolink:ChemicalSubstance piperidinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_589779 chebi_ph7_3 GO:1902979 biolink:BiologicalProcess mitotic DNA replication termination Any DNA replication termination involved in mitotic cell cycle DNA replication. go-plus.json DNA replication termination involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902979 GO:1902977 biolink:BiologicalProcess mitotic DNA replication preinitiation complex assembly Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle. go-plus.json DNA replication preinitiation complex formation involved in mitotic cell cycle|pre-IC complex assembly involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902977 GO:1902978 biolink:BiologicalProcess premeiotic DNA replication termination Any DNA replication termination involved in meiotic cell cycle DNA replication. go-plus.json DNA replication termination involved in meiotic DNA replication|DNA replication termination involved in meiotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902978 GO:1902975 biolink:BiologicalProcess mitotic DNA replication initiation Any DNA replication initiation involved in mitotic cell cycle DNA replication. go-plus.json DNA replication initiation involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902975 GO:1902976 biolink:BiologicalProcess premeiotic DNA replication preinitiation complex assembly Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle. go-plus.json pre-IC complex assembly involved in meiotic cell cycle|DNA replication preinitiation complex formation involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_1902976 GO:1902973 biolink:BiologicalProcess mitotic DNA replication DNA ligation Any DNA ligation involved in mitotic cell cycle DNA replication. go-plus.json DNA ligation involved in mitotic cell cycle DNA replication|DNA ligation involved in mitotic DNA replication http://purl.obolibrary.org/obo/GO_1902973 GO:1902974 biolink:BiologicalProcess meiotic DNA replication initiation Any DNA replication initiation involved in meiotic cell cycle DNA replication. go-plus.json premeiotic DNA replication initiation|DNA replication initiation involved in meiotic cell cycle DNA replication|meiotic DNA replication initiation|initiation of premeiotic DNA synthesis|initiation of premeiotic DNA replication|initiation of meiotic DNA synthesis|DNA replication initiation involved in meiotic DNA replication http://purl.obolibrary.org/obo/GO_1902974 GO:1902971 biolink:BiologicalProcess mitotic DNA replication DNA duplex unwinding Any DNA duplex unwinding involved in mitotic cell cycle DNA replication. go-plus.json DNA duplex unwinding involved in mitotic DNA replication|DNA duplex unwinding involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902971 GO:1902972 biolink:BiologicalProcess premeiotic DNA replication DNA ligation Any DNA ligation involved in meiotic cell cycle DNA replication. go-plus.json DNA ligation involved in meiotic DNA replication|DNA ligation involved in meiotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902972 CHEBI:13705 biolink:ChemicalSubstance acetoacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13705 chebi_ph7_3 GO:1902970 biolink:BiologicalProcess premeiotic DNA replication DNA duplex unwinding Any DNA duplex unwinding involved in meiotic cell cycle DNA replication. go-plus.json DNA duplex unwinding involved in meiotic DNA replication|DNA duplex unwinding involved in meiotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902970 CHEBI:72084 biolink:ChemicalSubstance phosphatidylserine 40:6(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72084 chebi_ph7_3 GO:1902988 biolink:BiologicalProcess neurofibrillary tangle assembly The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle. go-plus.json neurofibrillary tangle formation|star-shaped neurofibrillary tangle assembly|flame-shaped neurofibrillary tangle assembly|flame-shaped neurofibrillary tangle formation|star-shaped neurofibrillary tangle formation http://purl.obolibrary.org/obo/GO_1902988 GO:1902989 biolink:BiologicalProcess meiotic telomere maintenance via semi-conservative replication Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle. go-plus.json telomeric fork progression involved in meiotic cell cycle|equal telomere replication involved in meiotic cell cycle|telomeric replication fork progression involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_1902989 GO:1902986 biolink:BiologicalProcess regulation of lysine biosynthetic process via aminoadipic acid Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid. go-plus.json regulation of lysine biosynthesis, aminoadipic pathway|regulation of lysine biosynthetic process, aminoadipic pathway|regulation of lysine biosynthetic process, aminoadipic acid pathway|regulation of lysine biosynthesis, aminoadipic acid pathway|regulation of lysine formation via aminoadipic acid|regulation of lysine synthesis via aminoadipic acid|regulation of lysine anabolism via aminoadipic acid http://purl.obolibrary.org/obo/GO_1902986 GO:1902987 biolink:BiologicalProcess negative regulation of lysine biosynthetic process via aminoadipic acid Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid. go-plus.json negative regulation of lysine synthesis via aminoadipic acid|down-regulation of lysine synthesis via aminoadipic acid|inhibition of lysine formation via aminoadipic acid|down-regulation of lysine anabolism via aminoadipic acid|negative regulation of lysine anabolism via aminoadipic acid|downregulation of lysine biosynthesis, aminoadipic pathway|downregulation of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine synthesis via aminoadipic acid|down regulation of lysine biosynthetic process, aminoadipic acid pathway|down-regulation of lysine biosynthetic process via aminoadipic acid|down regulation of lysine biosynthesis, aminoadipic pathway|down regulation of lysine biosynthetic process, aminoadipic pathway|inhibition of lysine anabolism via aminoadipic acid|downregulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine biosynthesis, aminoadipic pathway|inhibition of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine formation via aminoadipic acid|downregulation of lysine biosynthetic process via aminoadipic acid|down regulation of lysine synthesis via aminoadipic acid|down-regulation of lysine biosynthesis, aminoadipic acid pathway|negative regulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine formation via aminoadipic acid|down-regulation of lysine biosynthetic process, aminoadipic acid pathway|negative regulation of lysine biosynthesis, aminoadipic acid pathway|down regulation of lysine biosynthetic process via aminoadipic acid|downregulation of lysine synthesis via aminoadipic acid|down regulation of lysine anabolism via aminoadipic acid|inhibition of lysine biosynthetic process via aminoadipic acid|downregulation of lysine anabolism via aminoadipic acid|inhibition of lysine biosynthetic process, aminoadipic acid pathway|inhibition of lysine biosynthesis, aminoadipic acid pathway|negative regulation of lysine biosynthesis, aminoadipic pathway|negative regulation of lysine biosynthetic process, aminoadipic pathway|down-regulation of lysine biosynthetic process, aminoadipic pathway|down-regulation of lysine biosynthesis, aminoadipic pathway|negative regulation of lysine formation via aminoadipic acid|down-regulation of lysine formation via aminoadipic acid http://purl.obolibrary.org/obo/GO_1902987 GO:1902984 biolink:BiologicalProcess pre-replicative complex assembly involved in premeiotic DNA replication Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication. go-plus.json nuclear pre-replicative complex assembly involved in meiotic cell cycle|pre-replicative complex assembly involved in meiosis|pre-RC complex assembly involved in meiosis|pre-replicative complex assembly involved in meiotic cell cycle DNA replication|pre-replicative complex formation involved in meiosis http://purl.obolibrary.org/obo/GO_1902984 GO:1902985 biolink:BiologicalProcess mitotic pre-replicative complex assembly Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication. go-plus.json pre-replicative complex assembly involved in mitotic cell cycle DNA replication|nuclear pre-replicative complex assembly involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902985 GO:1902982 biolink:BiologicalProcess DNA strand elongation involved in premeiotic DNA replication Any DNA strand elongation involved in meiotic cell cycle DNA replication. go-plus.json DNA strand elongation involved in meiotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902982 GO:1902983 biolink:BiologicalProcess DNA strand elongation involved in mitotic DNA replication Any DNA strand elongation involved in mitotic cell cycle DNA replication. go-plus.json DNA strand elongation involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902983 GO:1902980 biolink:BiologicalProcess synthesis of RNA primer involved in premeiotic DNA replication Any synthesis of RNA primer involved in meiotic cell cycle DNA replication. go-plus.json synthesis of RNA primer involved in meiotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902980 GO:1902981 biolink:BiologicalProcess synthesis of RNA primer involved in mitotic DNA replication Any synthesis of RNA primer involved in mitotic cell cycle DNA replication. go-plus.json synthesis of RNA primer involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1902981 GO:1902990 biolink:BiologicalProcess mitotic telomere maintenance via semi-conservative replication Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle. go-plus.json telomeric replication fork progression involved in mitotic cell cycle|telomeric fork progression involved in mitotic cell cycle|equal telomere replication involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1902990 GO:1902999 biolink:BiologicalProcess negative regulation of phospholipid efflux Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux. go-plus.json down regulation of phospholipid export|downregulation of phospholipid export|down regulation of phospholipid efflux|negative regulation of phospholipid export|down-regulation of phospholipid export|downregulation of phospholipid efflux|inhibition of phospholipid export|down-regulation of phospholipid efflux|inhibition of phospholipid efflux http://purl.obolibrary.org/obo/GO_1902999 GO:1902997 biolink:BiologicalProcess negative regulation of neurofibrillary tangle assembly Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly. go-plus.json inhibition of neurofibrillary tangle assembly|down-regulation of flame-shaped neurofibrillary tangle formation|negative regulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle assembly|negative regulation of star-shaped neurofibrillary tangle formation|down-regulation of star-shaped neurofibrillary tangle formation|down regulation of flame-shaped neurofibrillary tangle assembly|down regulation of star-shaped neurofibrillary tangle assembly|down regulation of neurofibrillary tangle assembly|downregulation of star-shaped neurofibrillary tangle assembly|down-regulation of neurofibrillary tangle formation|negative regulation of neurofibrillary tangle formation|inhibition of flame-shaped neurofibrillary tangle formation|inhibition of flame-shaped neurofibrillary tangle assembly|downregulation of neurofibrillary tangle assembly|downregulation of star-shaped neurofibrillary tangle formation|down regulation of star-shaped neurofibrillary tangle formation|down regulation of flame-shaped neurofibrillary tangle formation|down-regulation of star-shaped neurofibrillary tangle assembly|negative regulation of star-shaped neurofibrillary tangle assembly|downregulation of neurofibrillary tangle formation|down-regulation of neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle formation|negative regulation of flame-shaped neurofibrillary tangle assembly|down regulation of neurofibrillary tangle formation|down-regulation of flame-shaped neurofibrillary tangle assembly|inhibition of neurofibrillary tangle formation http://purl.obolibrary.org/obo/GO_1902997 GO:1902998 biolink:BiologicalProcess positive regulation of neurofibrillary tangle assembly Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly. go-plus.json positive regulation of flame-shaped neurofibrillary tangle assembly|upregulation of neurofibrillary tangle formation|up-regulation of star-shaped neurofibrillary tangle formation|up regulation of flame-shaped neurofibrillary tangle assembly|up-regulation of neurofibrillary tangle assembly|activation of flame-shaped neurofibrillary tangle formation|activation of star-shaped neurofibrillary tangle formation|upregulation of star-shaped neurofibrillary tangle assembly|activation of neurofibrillary tangle formation|up-regulation of neurofibrillary tangle formation|up-regulation of flame-shaped neurofibrillary tangle formation|upregulation of neurofibrillary tangle assembly|upregulation of flame-shaped neurofibrillary tangle assembly|positive regulation of star-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle assembly|positive regulation of star-shaped neurofibrillary tangle assembly|upregulation of flame-shaped neurofibrillary tangle formation|positive regulation of neurofibrillary tangle formation|up regulation of neurofibrillary tangle assembly|up-regulation of flame-shaped neurofibrillary tangle assembly|up regulation of neurofibrillary tangle formation|activation of neurofibrillary tangle assembly|activation of star-shaped neurofibrillary tangle assembly|upregulation of star-shaped neurofibrillary tangle formation|activation of flame-shaped neurofibrillary tangle assembly|up regulation of flame-shaped neurofibrillary tangle formation|up-regulation of star-shaped neurofibrillary tangle assembly|positive regulation of flame-shaped neurofibrillary tangle formation http://purl.obolibrary.org/obo/GO_1902998 GO:1902995 biolink:BiologicalProcess positive regulation of phospholipid efflux Any process that activates or increases the frequency, rate or extent of phospholipid efflux. go-plus.json upregulation of phospholipid efflux|up regulation of phospholipid export|activation of phospholipid export|positive regulation of phospholipid export|up regulation of phospholipid efflux|activation of phospholipid efflux|up-regulation of phospholipid export|upregulation of phospholipid export|up-regulation of phospholipid efflux http://purl.obolibrary.org/obo/GO_1902995 GO:1902996 biolink:BiologicalProcess regulation of neurofibrillary tangle assembly Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly. go-plus.json regulation of flame-shaped neurofibrillary tangle assembly|regulation of star-shaped neurofibrillary tangle assembly|regulation of star-shaped neurofibrillary tangle formation|regulation of flame-shaped neurofibrillary tangle formation|regulation of neurofibrillary tangle formation http://purl.obolibrary.org/obo/GO_1902996 GO:1902993 biolink:BiologicalProcess positive regulation of amyloid precursor protein catabolic process Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process. go-plus.json positive regulation of amyloid precursor protein breakdown|activation of amyloid precursor protein breakdown|up-regulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein catabolic process|activation of amyloid precursor protein catabolism|activation of amyloid precursor protein catabolic process|positive regulation of APP catabolism|up-regulation of amyloid precursor protein degradation|up regulation of APP catabolism|up regulation of APP catabolic process|positive regulation of APP catabolic process|activation of APP catabolic process|up-regulation of amyloid precursor protein breakdown|positive regulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein catabolism|up-regulation of amyloid precursor protein catabolic process|upregulation of amyloid precursor protein degradation|upregulation of APP catabolism|upregulation of amyloid precursor protein breakdown|up-regulation of APP catabolic process|upregulation of amyloid precursor protein catabolic process|upregulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein degradation|positive regulation of amyloid precursor protein degradation|up-regulation of APP catabolism|activation of amyloid precursor protein degradation|activation of APP catabolism|up regulation of amyloid precursor protein breakdown|upregulation of APP catabolic process http://purl.obolibrary.org/obo/GO_1902993 GO:1902994 biolink:BiologicalProcess regulation of phospholipid efflux Any process that modulates the frequency, rate or extent of phospholipid efflux. go-plus.json regulation of phospholipid export http://purl.obolibrary.org/obo/GO_1902994 GO:1902991 biolink:BiologicalProcess regulation of amyloid precursor protein catabolic process Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process. go-plus.json regulation of APP catabolic process|regulation of APP catabolism|regulation of amyloid precursor protein catabolism|regulation of amyloid precursor protein degradation|regulation of amyloid precursor protein breakdown http://purl.obolibrary.org/obo/GO_1902991 GO:1902992 biolink:BiologicalProcess negative regulation of amyloid precursor protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process. go-plus.json down regulation of APP catabolic process|negative regulation of APP catabolism|down-regulation of APP catabolism|down-regulation of amyloid precursor protein breakdown|negative regulation of amyloid precursor protein breakdown|downregulation of APP catabolic process|inhibition of amyloid precursor protein degradation|negative regulation of amyloid precursor protein catabolism|down-regulation of amyloid precursor protein catabolic process|down-regulation of amyloid precursor protein catabolism|downregulation of APP catabolism|inhibition of amyloid precursor protein breakdown|down-regulation of APP catabolic process|negative regulation of APP catabolic process|inhibition of amyloid precursor protein catabolic process|down regulation of APP catabolism|downregulation of amyloid precursor protein catabolism|inhibition of APP catabolism|down regulation of amyloid precursor protein degradation|inhibition of APP catabolic process|down regulation of amyloid precursor protein catabolism|downregulation of amyloid precursor protein degradation|inhibition of amyloid precursor protein catabolism|down regulation of amyloid precursor protein breakdown|down regulation of amyloid precursor protein catabolic process|downregulation of amyloid precursor protein breakdown|downregulation of amyloid precursor protein catabolic process|down-regulation of amyloid precursor protein degradation|negative regulation of amyloid precursor protein degradation http://purl.obolibrary.org/obo/GO_1902992 OBO:GOCHE_26348 biolink:OntologyClass substance with prosthetic group role go-plus.json http://purl.obolibrary.org/obo/GOCHE_26348 3_STAR CHEBI:13719 biolink:ChemicalSubstance acetylsalicylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_13719 chebi_ph7_3 CHEBI:13714 biolink:ChemicalSubstance 1-O-acetylmaltose go-plus.json http://purl.obolibrary.org/obo/CHEBI_13714 chebi_ph7_3 CHEBI:13711 biolink:ChemicalSubstance acetyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_13711 UBERON:0004819 biolink:AnatomicalEntity kidney epithelium the cellular avascular layer of the kidney luminar surfaces go-plus.json epithelium of kidney|kidney epithelial tissue|renal epithelium|epithelial tissue of kidney http://purl.obolibrary.org/obo/UBERON_0004819 UBERON:0004817 biolink:AnatomicalEntity lacrimal gland epithelium An epithelium that is part of a lacrimal gland [Automatically generated definition]. go-plus.json epithelial tissue of lacrimal gland|epithelium of lacrimal gland|lacrimal gland epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004817 UBERON:0004815 biolink:AnatomicalEntity lower respiratory tract epithelium An epithelium that is part of a lower respiratory tract [Automatically generated definition]. go-plus.json epithelial tissue of lower respiratory tract|lower respiratory tract epithelial tissue|epithelium of lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0004815 UBERON:0004816 biolink:AnatomicalEntity larynx epithelium An epithelium that is part of a larynx [Automatically generated definition]. go-plus.json laryngeal epithelium|epithelial tissue of larynx|epithelium of larynx|larynx epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004816 UBERON:0004813 biolink:AnatomicalEntity seminiferous tubule epithelium the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule go-plus.json male germinal epithelium|seminiferous epithelium|epithelium of seminiferous tubule of testis|epithelial tissue of seminiferous tubule of testis|testis germinal epithelium|epithelium of seminiferous tubule|epithelial tissue of seminiferous tubule|wall of seminiferous tubule|germinal epithelium (male)|seminiferous tubule epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004813 UBERON:0004814 biolink:AnatomicalEntity upper respiratory tract epithelium An epithelium that is part of a upper respiratory tract [Automatically generated definition]. go-plus.json upper respiratory tract epithelial tissue|epithelium of upper respiratory tract|epithelial tissue of upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0004814 GO:0034613 biolink:BiologicalProcess cellular protein localization Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. go-plus.json channel localizer activity|cellular protein localisation http://purl.obolibrary.org/obo/GO_0034613 goslim_drosophila GO:0010646 biolink:BiologicalProcess regulation of cell communication Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0010646 CHEBI:140311 biolink:ChemicalSubstance FMNH(.)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140311 chebi_ph7_3 GO:0034614 biolink:BiologicalProcess cellular response to reactive oxygen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. go-plus.json cellular response to reactive oxygen intermediate|cellular response to AOS|cellular response to ROS|cellular response to active oxygen species|cellular response to reactive oxidative species|cellular response to ROI http://purl.obolibrary.org/obo/GO_0034614 CHEBI:57290 biolink:ChemicalSubstance hydroxyacetone phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57290 chebi_ph7_3 GO:0010647 biolink:BiologicalProcess positive regulation of cell communication Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0010647 CHEBI:140312 biolink:ChemicalSubstance [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140312 chebi_ph7_3 GO:0010644 biolink:BiologicalProcess cell communication by electrical coupling The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010644 GO:0034615 biolink:CellularComponent GCH1 complex A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive. go-plus.json GTP cyclohydrolase I complex http://purl.obolibrary.org/obo/GO_0034615 GO:0034616 biolink:BiologicalProcess response to laminar fluid shear stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls. go-plus.json http://purl.obolibrary.org/obo/GO_0034616 GO:0010645 biolink:BiologicalProcess regulation of cell communication by chemical coupling Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010645 CHEBI:140310 biolink:ChemicalSubstance phenyl acetates go-plus.json http://purl.obolibrary.org/obo/CHEBI_140310 chebi_ph7_3 GO:0034617 biolink:MolecularActivity tetrahydrobiopterin binding Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions. go-plus.json sapropterin binding|H4biopterin binding|BH4 binding http://purl.obolibrary.org/obo/GO_0034617 GO:0034618 biolink:MolecularActivity arginine binding Binding to 2-amino-5-(carbamimidamido)pentanoic acid. go-plus.json Arg binding|aminopentanoic acid binding http://purl.obolibrary.org/obo/GO_0034618 GO:0010648 biolink:BiologicalProcess negative regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0010648 GO:0034619 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034619 GO:0010649 biolink:BiologicalProcess regulation of cell communication by electrical coupling Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010649 CHEBI:57286 biolink:ChemicalSubstance acetoacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57286 chebi_ph7_3 CHEBI:139319 biolink:ChemicalSubstance S-disulfanyl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139319 chebi_ph7_3 GO:0009650 biolink:BiologicalProcess UV protection Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV. go-plus.json ultraviolet tolerance|UV resistance|ultraviolet protection|ultraviolet resistance|UV tolerance http://purl.obolibrary.org/obo/GO_0009650 CHEBI:57287 biolink:ChemicalSubstance coenzyme A(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57287 chebi_ph7_3 GO:0009651 biolink:BiologicalProcess response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json salinity response|response to ionic osmotic stress http://purl.obolibrary.org/obo/GO_0009651 CHEBI:140317 biolink:ChemicalSubstance phenyl sulfate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140317 chebi_ph7_3 CHEBI:57284 biolink:ChemicalSubstance 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57284 chebi_ph7_3 GO:0009652 biolink:BiologicalProcess thigmotropism The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it. Wikipedia:Thigmotropism go-plus.json http://purl.obolibrary.org/obo/GO_0009652 GO:0009653 biolink:BiologicalProcess anatomical structure morphogenesis The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. Wikipedia:Morphogenesis go-plus.json morphogenesis|anatomical structure organization|embryogenesis and morphogenesis http://purl.obolibrary.org/obo/GO_0009653 GO:0010642 biolink:BiologicalProcess negative regulation of platelet-derived growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. go-plus.json negative regulation of platelet-derived growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0010642 GO:0034610 biolink:MolecularActivity oligodeoxyribonucleotidase activity Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates. go-plus.json DNA oligonucleotidase activity http://purl.obolibrary.org/obo/GO_0034610 GO:0010643 biolink:BiologicalProcess cell communication by chemical coupling The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010643 GO:0009654 biolink:CellularComponent photosystem II oxygen evolving complex A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ). Wikipedia:Oxygen_evolving_complex go-plus.json oxygen evolving complex|OEC (PSII) complex http://purl.obolibrary.org/obo/GO_0009654 CHEBI:57283 biolink:ChemicalSubstance N(alpha)-methyl-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57283 chebi_ph7_3 CHEBI:57280 biolink:ChemicalSubstance N(6)-lipoyl-L-lysinium(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_57280 chebi_ph7_3 GO:0009655 biolink:CellularComponent PSII associated light-harvesting complex II, core complex The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center. go-plus.json PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex|PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex|PSII associated light-harvesting complex II, core complex, LHCIId subcomplex http://purl.obolibrary.org/obo/GO_0009655 GO:0010640 biolink:BiologicalProcess regulation of platelet-derived growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. go-plus.json regulation of platelet-derived growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0010640 GO:0034611 biolink:MolecularActivity oligoribonucleotidase activity Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates. Reactome:R-HSA-9615042|Reactome:R-HSA-9009950 go-plus.json RNA oligonucleotidase activity http://purl.obolibrary.org/obo/GO_0034611 GO:0009656 biolink:CellularComponent PSII associated light-harvesting complex II, peripheral complex Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light. go-plus.json http://purl.obolibrary.org/obo/GO_0009656 CHEBI:57281 biolink:ChemicalSubstance N(6)-(S(8)-ammoniomethyldihydrolipoyl)-L-lysinium(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_57281 chebi_ph7_3 GO:0034612 biolink:BiologicalProcess response to tumor necrosis factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus. go-plus.json response to TNF http://purl.obolibrary.org/obo/GO_0034612 GO:0010641 biolink:BiologicalProcess positive regulation of platelet-derived growth factor receptor signaling pathway Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. go-plus.json positive regulation of platelet-derived growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0010641 CHEBI:140314 biolink:ChemicalSubstance 5'-triphosphoadenylyl-(2'->5')-adenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140314 GO:0009657 biolink:BiologicalProcess plastid organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid. go-plus.json plastid organisation|plastid organization and biogenesis http://purl.obolibrary.org/obo/GO_0009657 goslim_pir UBERON:0004822 biolink:AnatomicalEntity extrahepatic bile duct epithelium An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]. go-plus.json epithelial tissue of extrahepatic bile duct|epithelium of extrahepatic bile duct|extrahepatic bile duct epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004822 UBERON:0004823 biolink:AnatomicalEntity intrahepatic bile duct epithelium An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]. go-plus.json epithelial tissue of intrahepatic bile duct|epithelium of intrahepatic bile duct|intrahepatic bile duct epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004823 GO:0009658 biolink:BiologicalProcess chloroplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. go-plus.json chloroplast organisation|chloroplast organization and biogenesis http://purl.obolibrary.org/obo/GO_0009658 GO:0009659 biolink:BiologicalProcess leucoplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes. go-plus.json leucoplast organisation|leucoplast organization and biogenesis http://purl.obolibrary.org/obo/GO_0009659 UBERON:0004820 biolink:AnatomicalEntity bile duct epithelium Any epithelium that lines one of the bile ducts. go-plus.json epithelium of bile duct|epithelium of biliary duct|biliary duct epithelium http://purl.obolibrary.org/obo/UBERON_0004820 UBERON:0004821 biolink:AnatomicalEntity pulmonary alveolus epithelium The epithelial layer of the alveoli[MP]. The layer of cells covering the lining of the tiny air sacs at the end of the bronchioles[BTO]. go-plus.json pulmonary alveolus epithelium|alveolus epithelium|epithelial tissue of alveolus|epithelium of alveolus|pulmonary alveolar epithelium|epithelium of pulmonary alveolus|alveolus epithelial tissue|alveolar epithelium http://purl.obolibrary.org/obo/UBERON_0004821 CHEBI:57288 biolink:ChemicalSubstance acetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57288 chebi_ph7_3 CHEBI:57289 biolink:ChemicalSubstance blasticidin S(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57289 chebi_ph7_3 UBERON:0004808 biolink:AnatomicalEntity gastrointestinal system epithelium An epithelium that is part of a digestive system [Automatically generated definition]. go-plus.json epithelium of gastrointestinal system|epithelial tissue of gastrointestinal system|gastrointestinal system epithelial tissue|epithelial tissue of digestive system|digestive system epithelium|epithelium of digestive system|digestive system epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004808 UBERON:0004809 biolink:AnatomicalEntity salivary gland epithelium An epithelium that is part of a salivary gland [Automatically generated definition]. go-plus.json epithelium of salivary gland|salivary gland epithelial tissue|epithelial tissue of salivary gland http://purl.obolibrary.org/obo/UBERON_0004809 UBERON:0004806 biolink:AnatomicalEntity vas deferens epithelium An epithelium that is part of a vas deferens [Automatically generated definition]. go-plus.json deferent duct epithelium|vas deferens epithelial tissue|epithelium of deferent duct|epithelial tissue of deferent duct|deferent duct epithelial tissue|epithelial tissue of sperm duct|epithelium of vas deferen|epithelium of sperm duct|ductus deferens epithelium|epithelial tissue of vas deferen|vas deferen epithelial tissue|sperm duct epithelial tissue|sperm duct epithelium|epithelium of ductus deferens|epithelial tissue of ductus deferens|vas deferen epithelium|epithelial tissue of vas deferens|ductus deferens epithelial tissue|epithelium of vas deferens http://purl.obolibrary.org/obo/UBERON_0004806 UBERON:0004807 biolink:AnatomicalEntity respiratory system epithelium An epithelium that is part of a respiratory system [Automatically generated definition]. go-plus.json epithelial tissue of respiratory system|epithelium of respiratory system|respiratory system epithelial tissue|apparatus respiratorius epithelium|epithelium of apparatus respiratorius|epithelial tissue of apparatus respiratorius|apparatus respiratorius epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004807 UBERON:0004804 biolink:AnatomicalEntity oviduct epithelium An epithelium that is part of a oviduct [Automatically generated definition]. go-plus.json columnar epithelium of the fallopian tube|epithelium of fallopian tube|fallopian tube epithelium|epithelium of oviduct|epithelial tissue of oviduct|oviduct epithelial tissue|columnar epithelium of the oviduct|epithelium of uterine tube http://purl.obolibrary.org/obo/UBERON_0004804 UBERON:0004805 biolink:AnatomicalEntity seminal vesicle epithelium An epithelium that is part of a seminal vesicle [Automatically generated definition]. go-plus.json epithelium of seminal vesicle|epithelial tissue of seminal vesicle|seminal vesicle epithelial tissue|epithelium of seminal gland|seminal gland epithelium|epithelial tissue of seminal gland|seminal gland epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004805 UBERON:0004802 biolink:AnatomicalEntity respiratory tract epithelium the pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi go-plus.json respiratory epithelium|epithelium of respiratory tract|epithelial tissue of respiratory tract|respiratory tract epithelial tissue|airway epithelium http://purl.obolibrary.org/obo/UBERON_0004802 UBERON:0004803 biolink:AnatomicalEntity penis epithelium An epithelium that is part of a penis [Automatically generated definition]. go-plus.json epithelium of penis|epithelial tissue of penis|penis epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004803 GO:0010657 biolink:BiologicalProcess muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. go-plus.json muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010657 GO:0034602 biolink:MolecularActivity oxoglutarate dehydrogenase (NAD+) activity Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH. KEGG_REACTION:R08549|MetaCyc:2OXOGLUTARATEDEH-RXN|RHEA:27786|Reactome:R-HSA-71401|EC:1.2.1.105|Reactome:R-HSA-71037 go-plus.json http://purl.obolibrary.org/obo/GO_0034602 GO:0010658 biolink:BiologicalProcess striated muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. go-plus.json striated muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010658 GO:0034603 biolink:MolecularActivity pyruvate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H. go-plus.json http://purl.obolibrary.org/obo/GO_0034603 CHEBI:140301 biolink:ChemicalSubstance 7-hydroxyisoflavones 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140301 chebi_ph7_3 GO:0034604 biolink:MolecularActivity pyruvate dehydrogenase (NAD+) activity Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH. RHEA:28042|KEGG_REACTION:R00209|MetaCyc:PYRUVDEH-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0034604 GO:0010655 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010655 GO:0010656 biolink:BiologicalProcess negative regulation of muscle cell apoptotic process Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. go-plus.json negative regulation of muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010656 GO:0034605 biolink:BiologicalProcess cellular response to heat Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. go-plus.json cellular response to heat stress http://purl.obolibrary.org/obo/GO_0034605 GO:0034606 biolink:BiologicalProcess response to hermaphrodite contact The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate. go-plus.json http://purl.obolibrary.org/obo/GO_0034606 GO:0034607 biolink:BiologicalProcess turning behavior involved in mating The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. go-plus.json turning behavior during mating http://purl.obolibrary.org/obo/GO_0034607 GO:0010659 biolink:BiologicalProcess cardiac muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. go-plus.json cardiac muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010659 GO:0034608 biolink:BiologicalProcess vulval location Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate. go-plus.json http://purl.obolibrary.org/obo/GO_0034608 GO:0034609 biolink:BiologicalProcess spicule insertion Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva. go-plus.json http://purl.obolibrary.org/obo/GO_0034609 GO:0009670 biolink:MolecularActivity triose-phosphate:phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out). go-plus.json triose phosphate antiporter|triose phosphate translocator|TPT|dihydroxyacetone phosphate:phosphate antiporter activity http://purl.obolibrary.org/obo/GO_0009670 GO:0009660 biolink:BiologicalProcess amyloplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch. go-plus.json amyloplast organization and biogenesis|amyloplast organisation http://purl.obolibrary.org/obo/GO_0009660 CHEBI:57275 biolink:ChemicalSubstance dTDP-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57275 chebi_ph7_3 CHEBI:140308 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140308 chebi_ph7_3 GO:0009661 biolink:BiologicalProcess chromoplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments. go-plus.json chromoplast organization and biogenesis|chromoplast organisation http://purl.obolibrary.org/obo/GO_0009661 CHEBI:57276 biolink:ChemicalSubstance feruloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57276 chebi_ph7_3 CHEBI:140309 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140309 chebi_ph7_3 GO:0010650 biolink:BiologicalProcess positive regulation of cell communication by electrical coupling Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010650 CHEBI:57273 biolink:ChemicalSubstance GDP-beta-L-fucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57273 chebi_ph7_3 GO:0009662 biolink:BiologicalProcess etioplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions. go-plus.json etioplast organisation|etioplast organization and biogenesis http://purl.obolibrary.org/obo/GO_0009662 CHEBI:140306 biolink:ChemicalSubstance 2'-hydroxygenistein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140306 chebi_ph7_3 CHEBI:57274 biolink:ChemicalSubstance 3,5-dibromo-4-oxidobenzoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57274 chebi_ph7_3 GO:0009663 biolink:BiologicalProcess plasmodesma organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. go-plus.json plasmodesmata organization and biogenesis|plasmodesma organization and biogenesis|plasmodesma organisation http://purl.obolibrary.org/obo/GO_0009663 CHEBI:140304 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140304 chebi_ph7_3 GO:0010653 biolink:BiologicalProcess negative regulation of cell communication by chemical coupling Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010653 GO:0009664 biolink:BiologicalProcess plant-type cell wall organization A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana. go-plus.json cellulose and pectin-containing cell wall organization and biogenesis|cell wall organization and biogenesis|plant-type cell wall organisation|plant-type cell wall organization and biogenesis http://purl.obolibrary.org/obo/GO_0009664 CHEBI:57271 biolink:ChemicalSubstance indol-3-ylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57271 chebi_ph7_3 GO:0009665 biolink:BiologicalProcess plastid inheritance The partitioning of plastids between daughter cells at cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0009665 GO:0010654 biolink:BiologicalProcess apical cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote. go-plus.json http://purl.obolibrary.org/obo/GO_0010654 CHEBI:140305 biolink:ChemicalSubstance genistein 7-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140305 chebi_ph7_3 GO:0009666 biolink:BiologicalProcess plastid outer membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid. go-plus.json plastid outer membrane organization and biogenesis|plastid outer membrane organisation http://purl.obolibrary.org/obo/GO_0009666 CHEBI:140302 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140302 chebi_ph7_3 GO:0034600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034600 GO:0010651 biolink:BiologicalProcess negative regulation of cell communication by electrical coupling Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010651 GO:0010652 biolink:BiologicalProcess positive regulation of cell communication by chemical coupling Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010652 GO:0009667 biolink:BiologicalProcess plastid inner membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid. go-plus.json plastid inner membrane organization and biogenesis|plastid inner membrane organisation http://purl.obolibrary.org/obo/GO_0009667 GO:0034601 biolink:MolecularActivity oxoglutarate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H. EC:1.2.1.52 go-plus.json http://purl.obolibrary.org/obo/GO_0034601 CHEBI:140303 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140303 chebi_ph7_3 CHEBI:57270 biolink:ChemicalSubstance N,N-dihydroxy-L-tyrosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57270 chebi_ph7_3 GO:0009668 biolink:BiologicalProcess plastid membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid. go-plus.json plastid membrane organisation|plastid membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0009668 UBERON:0004811 biolink:AnatomicalEntity endometrium epithelium An epithelium that is part of an endometrium [Automatically generated definition]. go-plus.json epithelium of endometrium|epithelial tissue of endometrium|endometrium epithelial tissue|epithelium of tunica mucosa of endometrium|uterine epithelium http://purl.obolibrary.org/obo/UBERON_0004811 CHEBI:139323 biolink:ChemicalSubstance coelenterazine 2-hydroperoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_139323 chebi_ph7_3 GO:0009669 biolink:MolecularActivity sucrose:cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in). go-plus.json sucrose:monovalent cation symporter activity|sucrose permease activity http://purl.obolibrary.org/obo/GO_0009669 CHEBI:139324 biolink:ChemicalSubstance coelenterazine dioxetanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_139324 chebi_ph7_3 UBERON:0004810 biolink:AnatomicalEntity nephron tubule epithelium the cellular avascular layer of the renal tubule luminar surfaces go-plus.json kidney tubule epithelium http://purl.obolibrary.org/obo/UBERON_0004810 CHEBI:57279 biolink:ChemicalSubstance 3-ammonio-2-oxopropyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57279 chebi_ph7_3 CHEBI:57277 biolink:ChemicalSubstance 3-(3-hydroxyphenyl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57277 chebi_ph7_3 CHEBI:139321 biolink:ChemicalSubstance S-(sulfosulfanyl)-L-cysteine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139321 chebi_ph7_3 CHEBI:57278 biolink:ChemicalSubstance 3-acylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57278 chebi_ph7_3 GO:0010624 biolink:BiologicalProcess regulation of Schwann cell proliferation Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0010624 GO:0010625 biolink:BiologicalProcess positive regulation of Schwann cell proliferation Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0010625 GO:0010622 biolink:BiologicalProcess specification of ovule identity The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010622 GO:0010623 biolink:BiologicalProcess programmed cell death involved in cell development The activation of endogenous cellular processes that result in the death of a cell as part of its development. go-plus.json programmed cell death involved in development|developmental programmed cell death http://purl.obolibrary.org/obo/GO_0010623 GO:0010628 biolink:BiologicalProcess positive regulation of gene expression Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. go-plus.json http://purl.obolibrary.org/obo/GO_0010628 GO:0010629 biolink:BiologicalProcess negative regulation of gene expression Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. go-plus.json http://purl.obolibrary.org/obo/GO_0010629 GO:0010626 biolink:BiologicalProcess negative regulation of Schwann cell proliferation Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0010626 GO:0010627 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010627 CHEBI:57264 biolink:ChemicalSubstance 4-fluoro-L-threonine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57264 chebi_ph7_3 CHEBI:57265 biolink:ChemicalSubstance 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57265 chebi_ph7_3 CHEBI:57262 biolink:ChemicalSubstance 3-sn-phosphatidyl-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57262 chebi_ph7_3 CHEBI:33299 biolink:ChemicalSubstance alkaline earth molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33299 GO:0009630 biolink:BiologicalProcess gravitropism The orientation of plant parts under the stimulation of gravity. Wikipedia:Gravitropism go-plus.json geotropism http://purl.obolibrary.org/obo/GO_0009630 CHEBI:57263 biolink:ChemicalSubstance 4-carboxylatomethylenebut-2-en-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_57263 chebi_ph7_3 GO:0010620 biolink:BiologicalProcess negative regulation of transcription by transcription factor catabolism Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go-plus.json http://purl.obolibrary.org/obo/GO_0010620 CHEBI:57260 biolink:ChemicalSubstance 2-methylbut-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57260 chebi_ph7_3 GO:0009631 biolink:BiologicalProcess cold acclimation Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures. go-plus.json http://purl.obolibrary.org/obo/GO_0009631 GO:0009632 biolink:BiologicalProcess obsolete freezing tolerance OBSOLETE. (Was not defined before being made obsolete). go-plus.json freezing tolerance http://purl.obolibrary.org/obo/GO_0009632 CHEBI:57261 biolink:ChemicalSubstance 3,3',5'-triiodo-L-thyronine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57261 chebi_ph7_3 GO:0010621 biolink:BiologicalProcess negative regulation of transcription by transcription factor localization Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor. go-plus.json negative regulation of transcription by transcription factor localisation http://purl.obolibrary.org/obo/GO_0010621 GO:0009633 biolink:BiologicalProcess obsolete drought tolerance OBSOLETE. (Was not defined before being made obsolete). go-plus.json drought tolerance http://purl.obolibrary.org/obo/GO_0009633 GO:0009634 biolink:BiologicalProcess obsolete heavy metal sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json heavy metal sensitivity/resistance http://purl.obolibrary.org/obo/GO_0009634 GO:0009635 biolink:BiologicalProcess response to herbicide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants. go-plus.json herbicide susceptibility/resistance http://purl.obolibrary.org/obo/GO_0009635 UBERON:0004801 biolink:AnatomicalEntity cervix epithelium An epithelium that is part of a uterine cervix [Automatically generated definition]. go-plus.json cervical epithelium|cervical canal epithelial tissue|epithelium of cervix|cervical canal epithelium|cervix epithelial tissue http://purl.obolibrary.org/obo/UBERON_0004801 GO:0009636 biolink:BiologicalProcess response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. go-plus.json detoxification response|toxin resistance|toxin susceptibility/resistance http://purl.obolibrary.org/obo/GO_0009636 goslim_chembl GO:0009637 biolink:BiologicalProcess response to blue light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. go-plus.json response to blue light stimulus http://purl.obolibrary.org/obo/GO_0009637 CHEBI:33292 biolink:ChemicalSubstance fuel go-plus.json http://purl.obolibrary.org/obo/CHEBI_33292 GO:0009638 biolink:BiologicalProcess phototropism The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it. Wikipedia:Phototropism go-plus.json http://purl.obolibrary.org/obo/GO_0009638 GO:0009639 biolink:BiologicalProcess response to red or far red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0009639 CHEBI:57268 biolink:ChemicalSubstance beta-L-fucose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57268 chebi_ph7_3 CHEBI:57269 biolink:ChemicalSubstance N,N'-diacetylchitobiosyldiphosphonatodolichol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57269 chebi_ph7_3 CHEBI:57266 biolink:ChemicalSubstance (-)-usnic acid(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57266 chebi_ph7_3 CHEBI:33295 biolink:ChemicalSubstance diagnostic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_33295 CHEBI:33296 biolink:ChemicalSubstance alkali metal molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33296 CHEBI:57267 biolink:ChemicalSubstance beta-D-fructofuranose 2-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57267 chebi_ph7_3 GO:0010635 biolink:BiologicalProcess regulation of mitochondrial fusion Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0010635 GO:0010636 biolink:BiologicalProcess positive regulation of mitochondrial fusion Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0010636 GO:0010633 biolink:BiologicalProcess negative regulation of epithelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0010633 GO:0010634 biolink:BiologicalProcess positive regulation of epithelial cell migration Any process that activates or increases the frequency, rate or extent of epithelial cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0010634 GO:0010639 biolink:BiologicalProcess negative regulation of organelle organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. go-plus.json negative regulation of organelle organisation|negative regulation of organelle organization and biogenesis http://purl.obolibrary.org/obo/GO_0010639 GO:0010637 biolink:BiologicalProcess negative regulation of mitochondrial fusion Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0010637 GO:0010638 biolink:BiologicalProcess positive regulation of organelle organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. go-plus.json positive regulation of organelle organization and biogenesis|positive regulation of organelle organisation http://purl.obolibrary.org/obo/GO_0010638 CHEBI:57253 biolink:ChemicalSubstance (R)-2-benzylsuccinyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57253 chebi_ph7_3 CHEBI:57254 biolink:ChemicalSubstance (R)-phenyllactoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57254 chebi_ph7_3 GO:0009640 biolink:BiologicalProcess photomorphogenesis The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis. Wikipedia:Photomorphogenesis go-plus.json plant development in response to light http://purl.obolibrary.org/obo/GO_0009640 CHEBI:57251 biolink:ChemicalSubstance (3S)-3-hydroxy-L-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57251 chebi_ph7_3 CHEBI:57252 biolink:ChemicalSubstance (E)-cinnamoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57252 chebi_ph7_3 GO:0009641 biolink:BiologicalProcess shade avoidance Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome. Wikipedia:Shade_avoidance go-plus.json http://purl.obolibrary.org/obo/GO_0009641 GO:0009642 biolink:BiologicalProcess response to light intensity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0009642 CHEBI:139304 biolink:ChemicalSubstance 2-hydroxyhexanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139304 GO:0010631 biolink:BiologicalProcess epithelial cell migration The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0010631 GO:0009643 biolink:BiologicalProcess photosynthetic acclimation A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light. go-plus.json light acclimatization|photoacclimation http://purl.obolibrary.org/obo/GO_0009643 GO:0010632 biolink:BiologicalProcess regulation of epithelial cell migration Any process that modulates the frequency, rate or extent of epithelial cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0010632 GO:0009644 biolink:BiologicalProcess response to high light intensity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0009644 GO:0009645 biolink:BiologicalProcess response to low light intensity stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2. go-plus.json http://purl.obolibrary.org/obo/GO_0009645 GO:0010630 biolink:BiologicalProcess regulation of transcription, start site selection Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template. go-plus.json http://purl.obolibrary.org/obo/GO_0010630 GO:0009646 biolink:BiologicalProcess response to absence of light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli. go-plus.json response to darkness http://purl.obolibrary.org/obo/GO_0009646 CHEBI:139300 biolink:ChemicalSubstance (+)-jasmonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139300 CHEBI:139301 biolink:ChemicalSubstance N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139301 GO:0009647 biolink:BiologicalProcess skotomorphogenesis The control of plant growth, development, and differentiation in response to growth in darkness. go-plus.json etiolation http://purl.obolibrary.org/obo/GO_0009647 GO:0009648 biolink:BiologicalProcess photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species. Wikipedia:Photoperiodism go-plus.json response to night length|response to day length|response to photoperiod http://purl.obolibrary.org/obo/GO_0009648 CHEBI:57259 biolink:ChemicalSubstance 2-deoxy-alpha-D-ribose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57259 chebi_ph7_3 CHEBI:139302 biolink:ChemicalSubstance N-[(3R)-jasmonyl]-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139302 GO:0009649 biolink:BiologicalProcess entrainment of circadian clock The synchronization of a circadian rhythm to environmental time cues such as light. go-plus.json regulation of circadian rhythm phase http://purl.obolibrary.org/obo/GO_0009649 CHEBI:139303 biolink:ChemicalSubstance 2-hydroxybutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139303 CHEBI:57257 biolink:ChemicalSubstance 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57257 chebi_ph7_3 CHEBI:57258 biolink:ChemicalSubstance 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57258 chebi_ph7_3 CHEBI:57255 biolink:ChemicalSubstance 5-(2-carboxylatoethyl)-4-oxo-4,5-dihydro-1H-imidazol-5-ide go-plus.json http://purl.obolibrary.org/obo/CHEBI_57255 GO:0010608 biolink:BiologicalProcess posttranscriptional regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0010608 GO:0010609 biolink:BiologicalProcess mRNA localization resulting in posttranscriptional regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell. go-plus.json mRNA localisation resulting in posttranscriptional regulation of gene expression|posttranscriptional regulation of gene expression by mRNA localisation|posttranscriptional regulation of gene expression by mRNA localization http://purl.obolibrary.org/obo/GO_0010609 UBERON:0004859 biolink:AnatomicalEntity eye gland A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid. go-plus.json gland of eye|eye-associated gland http://purl.obolibrary.org/obo/UBERON_0004859 UBERON:0004857 biolink:AnatomicalEntity skeletal muscle connective tissue A connective tissue that surrounds a skeletal muscle tissue. go-plus.json skeletal muscle tissue connective tissue|portion of connective tissue of skeletal muscle tissue|skeletal muscle tissue portion of connective tissue|connective tissue of skeletal muscle|textus connectivus of skeletal muscle tissue|skeletal muscle tissue textus connectivus|skeletal muscle interstitum|skeletal muscle portion of connective tissue|textus connectivus of skeletal muscle|connective tissue of skeletal muscle tissue|skeletal muscle interstitial tissue|portion of connective tissue of skeletal muscle|skeletal muscle textus connectivus http://purl.obolibrary.org/obo/UBERON_0004857 GO:0010602 biolink:BiologicalProcess regulation of 1-aminocyclopropane-1-carboxylate metabolic process Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. go-plus.json http://purl.obolibrary.org/obo/GO_0010602 GO:0010603 biolink:BiologicalProcess regulation of cytoplasmic mRNA processing body assembly Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. go-plus.json http://purl.obolibrary.org/obo/GO_0010603 GO:0010600 biolink:BiologicalProcess regulation of auxin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. go-plus.json http://purl.obolibrary.org/obo/GO_0010600 GO:0010601 biolink:BiologicalProcess positive regulation of auxin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. go-plus.json http://purl.obolibrary.org/obo/GO_0010601 GO:0010606 biolink:BiologicalProcess positive regulation of cytoplasmic mRNA processing body assembly Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. go-plus.json http://purl.obolibrary.org/obo/GO_0010606 GO:0010607 biolink:BiologicalProcess negative regulation of cytoplasmic mRNA processing body assembly Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. go-plus.json http://purl.obolibrary.org/obo/GO_0010607 GO:0010604 biolink:BiologicalProcess positive regulation of macromolecule metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json http://purl.obolibrary.org/obo/GO_0010604 GO:0010605 biolink:BiologicalProcess negative regulation of macromolecule metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json http://purl.obolibrary.org/obo/GO_0010605 CHEBI:33275 biolink:ChemicalSubstance beta-tocotrienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33275 chebi_ph7_3 CHEBI:33276 biolink:ChemicalSubstance delta-tocotrienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33276 chebi_ph7_3 CHEBI:33277 biolink:ChemicalSubstance gamma-tocotrienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33277 chebi_ph7_3 CHEBI:33279 biolink:ChemicalSubstance vitamin D5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_33279 chebi_ph7_3 GO:0009610 biolink:BiologicalProcess response to symbiotic fungus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism. go-plus.json response to symbiotic fungi http://purl.obolibrary.org/obo/GO_0009610 GO:0009611 biolink:BiologicalProcess response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. go-plus.json physiological response to wounding http://purl.obolibrary.org/obo/GO_0009611 GO:0009612 biolink:BiologicalProcess response to mechanical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. go-plus.json chemi-mechanical coupling|mechanical stimulus response http://purl.obolibrary.org/obo/GO_0009612 GO:0009613 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009613 GO:0009614 biolink:BiologicalProcess obsolete disease resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json disease resistance http://purl.obolibrary.org/obo/GO_0009614 UBERON:0004867 biolink:AnatomicalEntity orbital cavity Anatomical cavity bounded by the orbital region of the cranium and forming the location of some or all of the eye. go-plus.json orbit http://purl.obolibrary.org/obo/UBERON_0004867 UBERON:0004864 biolink:AnatomicalEntity vasculature of retina A vasculature that is part of a retina [Automatically generated definition]. go-plus.json vasa sanguinea retinae|set of blood vessels of retina|retina vasculature of camera-type eye|retinal blood vessels set|retinal blood vessels|retina vasculature|set of retinal blood vessels|retinal vasculature http://purl.obolibrary.org/obo/UBERON_0004864 GO:0009615 biolink:BiologicalProcess response to virus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. go-plus.json response to viruses http://purl.obolibrary.org/obo/GO_0009615 CHEBI:57248 biolink:ChemicalSubstance echinocandin go-plus.json http://purl.obolibrary.org/obo/CHEBI_57248 GO:0009616 biolink:BiologicalProcess RNAi-mediated antiviral immune response RNA-mediated post-transcriptional gene silencing mechanism that protects against foreign organism invasion by restricting viral replication and dissemination. go-plus.json RNAi-mediated antiviral immunity|viral gene silencing in virus induced gene silencing|virus induced gene silencing|VIGS|virus-induced gene silencing|viral triggering of virus induced gene silencing http://purl.obolibrary.org/obo/GO_0009616 CHEBI:33270 biolink:ChemicalSubstance alpha-tocotrienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33270 chebi_ph7_3 UBERON:0004862 biolink:AnatomicalEntity left lung alveolus An alveolus that is part of a left lung [Automatically generated definition]. go-plus.json alveolus of lobe of left lung|alveolus of left lung http://purl.obolibrary.org/obo/UBERON_0004862 GO:0009617 biolink:BiologicalProcess response to bacterium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. go-plus.json response to bacteria http://purl.obolibrary.org/obo/GO_0009617 GO:0009618 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009618 UBERON:0004863 biolink:AnatomicalEntity thoracic sympathetic nerve trunk A sympathetic nerve trunk that is part of a thorax [Automatically generated definition]. go-plus.json sympathetic nerve trunk of thorax|thoracic sympathetic chain|nerve trunk of sympathetic nervous system of thorax|thorax sympathetic nerve trunk|nerve trunk of sympathetic part of autonomic division of nervous system of thorax|thoracic part of sympathetic trunk|thorax nerve trunk of sympathetic nervous system|sympathetic nervous system nerve trunk of thorax|thorax sympathetic nervous system nerve trunk|thorax nerve trunk of sympathetic part of autonomic division of nervous system|thoracic sympathetic trunk http://purl.obolibrary.org/obo/UBERON_0004863 CHEBI:33272 biolink:ChemicalSubstance ketimine go-plus.json http://purl.obolibrary.org/obo/CHEBI_33272 GO:0009619 biolink:BiologicalProcess obsolete resistance to pathogenic bacteria OBSOLETE. (Was not defined before being made obsolete). go-plus.json resistance to pathogenic bacteria http://purl.obolibrary.org/obo/GO_0009619 CHEBI:33273 biolink:ChemicalSubstance polyatomic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_33273 UBERON:0004861 biolink:AnatomicalEntity right lung alveolus An alveolus that is part of a right lung [Automatically generated definition]. go-plus.json alveolus of right lung http://purl.obolibrary.org/obo/UBERON_0004861 GO:0010619 biolink:BiologicalProcess adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). go-plus.json activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway|activation of adenylate cyclase activity by glucose-triggered G-protein signalling pathway|activation of adenylate cyclase activity by glucose involved in G-protein signaling|glucose-sensing PKA pathway http://purl.obolibrary.org/obo/GO_0010619 UBERON:0004848 biolink:AnatomicalEntity respiratory system arterial endothelium An endothelium of artery that is part of a respiratory system [Automatically generated definition]. go-plus.json artery endothelium of apparatus respiratorius|respiratory system artery endothelium|endothelium of artery of respiratory system|endothelium of artery of apparatus respiratorius|respiratory system endothelium of artery|artery endothelium of respiratory system|arterial endothelium of respiratory system|apparatus respiratorius artery endothelium|apparatus respiratorius endothelium of artery|arterial endothelium of apparatus respiratorius|apparatus respiratorius arterial endothelium http://purl.obolibrary.org/obo/UBERON_0004848 UBERON:0004849 biolink:AnatomicalEntity respiratory system venous endothelium An endothelium of vein that is part of a respiratory system [Automatically generated definition]. go-plus.json respiratory system endothelium of vein|vein endothelium of respiratory system|venous endothelium of apparatus respiratorius|venous endothelium of respiratory system|vein endothelium of apparatus respiratorius|apparatus respiratorius vein endothelium|apparatus respiratorius endothelium of vein|apparatus respiratorius venous endothelium|endothelium of vein of apparatus respiratorius|respiratory system vein endothelium|endothelium of vein of respiratory system http://purl.obolibrary.org/obo/UBERON_0004849 GO:0010613 biolink:BiologicalProcess positive regulation of cardiac muscle hypertrophy Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0010613 GO:0010614 biolink:BiologicalProcess negative regulation of cardiac muscle hypertrophy Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0010614 GO:0010611 biolink:BiologicalProcess regulation of cardiac muscle hypertrophy Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0010611 GO:0010612 biolink:BiologicalProcess regulation of cardiac muscle adaptation Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. go-plus.json http://purl.obolibrary.org/obo/GO_0010612 GO:0010617 biolink:BiologicalProcess circadian regulation of calcium ion oscillation Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours. go-plus.json circadian regulation of Ca2+ oscillation|circadian regulation of cytosolic calcium ion homeostasis|circadian regulation of cytosolic free calcium ion oscillation|circadian regulation of [Ca2+]cyt oscillation http://purl.obolibrary.org/obo/GO_0010617 GO:0010618 biolink:BiologicalProcess aerenchyma formation The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0010618 GO:0010615 biolink:BiologicalProcess positive regulation of cardiac muscle adaptation Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. go-plus.json http://purl.obolibrary.org/obo/GO_0010615 GO:0010616 biolink:BiologicalProcess negative regulation of cardiac muscle adaptation Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. go-plus.json http://purl.obolibrary.org/obo/GO_0010616 CHEBI:33286 biolink:ChemicalSubstance agrochemical go-plus.json http://purl.obolibrary.org/obo/CHEBI_33286 CHEBI:33287 biolink:ChemicalSubstance fertilizer go-plus.json http://purl.obolibrary.org/obo/CHEBI_33287 CHEBI:33288 biolink:ChemicalSubstance rodenticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33288 CHEBI:33289 biolink:ChemicalSubstance avicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33289 GO:0009620 biolink:BiologicalProcess response to fungus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. go-plus.json response to fungi http://purl.obolibrary.org/obo/GO_0009620 GO:0010610 biolink:BiologicalProcess regulation of mRNA stability involved in response to stress Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance. go-plus.json http://purl.obolibrary.org/obo/GO_0010610 GO:0009621 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009621 GO:0009622 biolink:BiologicalProcess obsolete resistance to pathogenic fungi OBSOLETE. (Was not defined before being made obsolete). go-plus.json resistance to pathogenic fungi http://purl.obolibrary.org/obo/GO_0009622 GO:0009623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009623 GO:0009624 biolink:BiologicalProcess response to nematode Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode. go-plus.json response to nematodes http://purl.obolibrary.org/obo/GO_0009624 GO:0009625 biolink:BiologicalProcess response to insect Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect. go-plus.json response to insects http://purl.obolibrary.org/obo/GO_0009625 CHEBI:33280 biolink:ChemicalSubstance molecular messenger go-plus.json http://purl.obolibrary.org/obo/CHEBI_33280 GO:0009626 biolink:BiologicalProcess plant-type hypersensitive response The rapid, localized death of plant cells in response to invasion by a pathogen. go-plus.json HR-PCD|plant hypersensitive response|HR http://purl.obolibrary.org/obo/GO_0009626 GO:0009627 biolink:BiologicalProcess systemic acquired resistance The salicylic acid mediated response to a pathogen which confers broad spectrum resistance. Wikipedia:Systemic_acquired_resistance go-plus.json salicylic acid-dependent systemic resistance http://purl.obolibrary.org/obo/GO_0009627 UBERON:0004854 biolink:AnatomicalEntity gastrointestinal system mesentery A mesentery that is part of a digestive system [Automatically generated definition]. go-plus.json mesentery of digestive system|digestive system mesentery|mesentery of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0004854 CHEBI:33281 biolink:ChemicalSubstance antimicrobial agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_33281 GO:0009628 biolink:BiologicalProcess response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. go-plus.json response to abiotic stress http://purl.obolibrary.org/obo/GO_0009628 gocheck_do_not_manually_annotate|goslim_plant|goslim_metagenomics UBERON:0004851 biolink:AnatomicalEntity aorta endothelium the thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall go-plus.json adult aorta endothelium|aortic endothelium|endothelium of aorta|endothelium of trunk of aortic tree|trunk of systemic arterial tree endothelium|endothelium of adult aorta|trunk of aortic tree endothelium|endothelium of trunk of systemic arterial tree http://purl.obolibrary.org/obo/UBERON_0004851 CHEBI:33282 biolink:ChemicalSubstance antibacterial agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_33282 UBERON:0004852 biolink:AnatomicalEntity cardiovascular system endothelium An endothelium that is part of the cardiovascular system. go-plus.json endothelia|vascular endothelia http://purl.obolibrary.org/obo/UBERON_0004852 GO:0009629 biolink:BiologicalProcess response to gravity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. go-plus.json response to gravitational stimulus http://purl.obolibrary.org/obo/GO_0009629 CHEBI:33284 biolink:ChemicalSubstance nutrient go-plus.json http://purl.obolibrary.org/obo/CHEBI_33284 UBERON:0004850 biolink:AnatomicalEntity lymph node endothelium An endothelium that is part of a lymph node [Automatically generated definition]. go-plus.json endothelium of lymph node http://purl.obolibrary.org/obo/UBERON_0004850 CHEBI:33285 biolink:ChemicalSubstance heteroorganic entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33285 UBERON:0004835 biolink:AnatomicalEntity epididymis smooth muscle A portion of smooth muscle tissue that is part of a epididymis [Automatically generated definition]. go-plus.json epididymis non-striated muscle|epididymis smooth muscle tissue|involuntary muscle of epididymis|epididymis involuntary muscle|non-striated muscle of epididymis|smooth muscle of epididymis|smooth muscle tissue of epididymis http://purl.obolibrary.org/obo/UBERON_0004835 GO:0044005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044005 GO:0044006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044006 GO:0044003 biolink:BiologicalProcess modulation by symbiont of host process The process in which a symbiont organism effects a change in the structure or processes of its host organism. go-plus.json modification by symbiont of host morphology or physiology|regulation by symbiont of host system process|pathogenesis|modification by symbiont of host biological process|disruption by symbiont of host cell|modulation by symbiont of host system process http://purl.obolibrary.org/obo/GO_0044003 GO:0044004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044004 GO:0044001 biolink:BiologicalProcess migration in host The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json migration within host http://purl.obolibrary.org/obo/GO_0044001 GO:0044002 biolink:BiologicalProcess acquisition of nutrients from host The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044002 GO:0044000 biolink:BiologicalProcess movement in host The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json movement of symbiont in host|symbiont movement within host|movement of symbiont within host|movement within host|symbiont movement in host http://purl.obolibrary.org/obo/GO_0044000 CHEBI:33253 biolink:ChemicalSubstance nucleon go-plus.json http://purl.obolibrary.org/obo/CHEBI_33253 CHEBI:33255 biolink:ChemicalSubstance alkylmercury compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33255 CHEBI:33256 biolink:ChemicalSubstance primary amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33256 GO:0044009 biolink:BiologicalProcess obsolete viral transmission by vector OBSOLETE. The transfer of virions by means of an organism (often an insect or other animal) in order to create new infection. go-plus.json http://purl.obolibrary.org/obo/GO_0044009 CHEBI:33257 biolink:ChemicalSubstance secondary amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33257 GO:0044007 biolink:BiologicalProcess obsolete dissemination or transmission of symbiont from host OBSOLETE. The movement of an organism from a host to another host or from a host to another place in the environment. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json dissemination or transmission of organism from host http://purl.obolibrary.org/obo/GO_0044007 CHEBI:33259 biolink:ChemicalSubstance elemental molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33259 GO:0044008 biolink:BiologicalProcess obsolete dissemination or transmission of symbiont from host by vector OBSOLETE. The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json dissemination or transmission of organism from host by vector http://purl.obolibrary.org/obo/GO_0044008 CHEBI:33250 biolink:ChemicalSubstance atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_33250 CHEBI:33251 biolink:ChemicalSubstance monoatomic hydrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33251 CHEBI:33252 biolink:ChemicalSubstance atomic nucleus go-plus.json http://purl.obolibrary.org/obo/CHEBI_33252 CHEBI:47896 biolink:ChemicalSubstance pyridine nucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_47896 UBERON:0004829 biolink:AnatomicalEntity urethra skeletal muscle tissue A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]. go-plus.json skeletal muscle tissue of urethra|urethral skeletal muscle|skeletal muscle of urethra|urethra skeletal muscle tissue|urethra skeletal muscle http://purl.obolibrary.org/obo/UBERON_0004829 CHEBI:47898 biolink:ChemicalSubstance 4'-epidoxorubicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_47898 UBERON:0004827 biolink:AnatomicalEntity thyroid gland medulla A medulla that is part of a thyroid [Automatically generated definition]. go-plus.json thyroid follicle medulla|thyroid medulla|medulla of thyroid gland|medulla of thyroid gland follicle|thyroid gland follicle medulla|medulla of thyroid follicle|medulla of thyroid http://purl.obolibrary.org/obo/UBERON_0004827 CHEBI:47899 biolink:ChemicalSubstance red chlorophyll catabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_47899 GO:0044016 biolink:MolecularActivity histone acetyltransferase activity (H3-K4 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4). go-plus.json histone lysine N-acetyltransferase activity (H3-K4 specific) http://purl.obolibrary.org/obo/GO_0044016 GO:0044017 biolink:MolecularActivity histone acetyltransferase activity (H3-K27 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27). go-plus.json histone lysine N-acetyltransferase activity (H3-K27 specific) http://purl.obolibrary.org/obo/GO_0044017 GO:0044014 biolink:MolecularActivity histone acetyltransferase activity (H2B-K5 specific) Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5). go-plus.json histone lysine N-acetyltransferase activity (H2B-K5 specific) http://purl.obolibrary.org/obo/GO_0044014 GO:0044015 biolink:MolecularActivity histone acetyltransferase activity (H2B-K12 specific) Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12). go-plus.json histone lysine N-acetyltransferase activity (H2B-K12 specific) http://purl.obolibrary.org/obo/GO_0044015 GO:0044012 biolink:MolecularActivity histone acetyltransferase activity (H2A-K9 specific) Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9). go-plus.json histone lysine N-acetyltransferase activity (H2A-K9 specific) http://purl.obolibrary.org/obo/GO_0044012 GO:0044013 biolink:MolecularActivity H2B histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine. go-plus.json H2B histone lysine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0044013 CHEBI:47891 biolink:ChemicalSubstance steroid acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47891 GO:0044010 biolink:BiologicalProcess single-species biofilm formation A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. go-plus.json bfp-dependent aggregation|bundle-forming pili-dependent aggregation|type IV pili-dependent aggregation|bundle-forming fimbriae-dependent aggregation|auto-aggregation|tfp-dependent aggregation http://purl.obolibrary.org/obo/GO_0044010 CHEBI:47892 biolink:ChemicalSubstance 4'-O-beta-D-glucosyl-cis-p-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47892 chebi_ph7_3 GO:0044011 biolink:BiologicalProcess single-species biofilm formation on inanimate substrate A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0044011 CHEBI:47893 biolink:ChemicalSubstance 4-O-beta-D-glucosyl-4-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47893 chebi_ph7_3 CHEBI:33264 biolink:ChemicalSubstance monoatomic oxygen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33264 CHEBI:33265 biolink:ChemicalSubstance triatomic oxygen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33265 CHEBI:33266 biolink:ChemicalSubstance diatomic nitrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33266 CHEBI:33267 biolink:ChemicalSubstance elemental nitrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33267 GO:0044018 biolink:MolecularActivity histone acetyltransferase activity (H3-K36 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36). go-plus.json histone lysine N-acetyltransferase activity (H3-K36 specific) http://purl.obolibrary.org/obo/GO_0044018 GO:0009600 biolink:BiologicalProcess detection of nematode The series of events in which a stimulus from a nematode is received and converted into a molecular signal. go-plus.json perception of nematode http://purl.obolibrary.org/obo/GO_0009600 GO:0009601 biolink:BiologicalProcess detection of insect The series of events in which a stimulus from an insect is received and converted into a molecular signal. go-plus.json perception of insect http://purl.obolibrary.org/obo/GO_0009601 GO:0044019 biolink:MolecularActivity histone acetyltransferase activity (H3-K72 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72). go-plus.json histone lysine N-acetyltransferase activity (H3-K72 specific) http://purl.obolibrary.org/obo/GO_0044019 GO:0009602 biolink:BiologicalProcess detection of symbiont The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json perception of symbiont|recognition of symbiont http://purl.obolibrary.org/obo/GO_0009602 UBERON:0004833 biolink:AnatomicalEntity lip skeletal muscle A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]. go-plus.json skeletal muscle tissue of lip|lip skeletal muscle tissue|skeletal muscle of lip http://purl.obolibrary.org/obo/UBERON_0004833 GO:0009603 biolink:BiologicalProcess detection of symbiotic fungus The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal. go-plus.json perception of symbiotic fungi|perception of symbiotic fungus|detection of symbiotic fungi http://purl.obolibrary.org/obo/GO_0009603 UBERON:0004834 biolink:AnatomicalEntity hepatic duct smooth muscle Smooth muscle tissue in all or part of a hepatic duct. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004834 GO:0009604 biolink:BiologicalProcess detection of symbiotic bacterium The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal. go-plus.json detection of symbiotic bacteria|perception of symbiotic bacteria|perception of symbiotic bacterium http://purl.obolibrary.org/obo/GO_0009604 UBERON:0004831 biolink:AnatomicalEntity esophagus skeletal muscle A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]. go-plus.json skeletal muscle of esophagus|esophagus skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0004831 UBERON:0004832 biolink:AnatomicalEntity anal region skeletal muscle A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]. go-plus.json skeletal muscle tissue of anal region|skeletal muscle of anal part of perineum|anal triangle skeletal muscle tissue|skeletal muscle of anal region|skeletal muscle tissue of anal triangle|anal part of perineum skeletal muscle|anal region skeletal muscle tissue|skeletal muscle of anal triangle|anal part of perineum skeletal muscle tissue|skeletal muscle tissue of anal part of perineum|anal triangle skeletal muscle http://purl.obolibrary.org/obo/UBERON_0004832 GO:0009605 biolink:BiologicalProcess response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. go-plus.json response to environmental stimulus http://purl.obolibrary.org/obo/GO_0009605 gocheck_do_not_manually_annotate|goslim_plant|goslim_drosophila GO:0009606 biolink:BiologicalProcess tropism The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it. Wikipedia:Tropism go-plus.json http://purl.obolibrary.org/obo/GO_0009606 goslim_plant CHEBI:33260 biolink:ChemicalSubstance elemental hydrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33260 UBERON:0004830 biolink:AnatomicalEntity respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]. go-plus.json skeletal muscle of respiratory system|skeletal muscle tissue of apparatus respiratorius|skeletal muscle tissue of respiratory system|skeletal muscle of apparatus respiratorius|respiratory system skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0004830 GO:0009607 biolink:BiologicalProcess response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. go-plus.json response to biotic stress http://purl.obolibrary.org/obo/GO_0009607 gocheck_do_not_manually_annotate|goslim_plant|goslim_metagenomics CHEBI:33261 biolink:ChemicalSubstance organosulfur compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_33261 GO:0009608 biolink:BiologicalProcess response to symbiont Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json response of host to symbiont http://purl.obolibrary.org/obo/GO_0009608 CHEBI:33262 biolink:ChemicalSubstance elemental oxygen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33262 CHEBI:33263 biolink:ChemicalSubstance diatomic oxygen go-plus.json http://purl.obolibrary.org/obo/CHEBI_33263 GO:0009609 biolink:BiologicalProcess response to symbiotic bacterium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism. go-plus.json response to symbiotic bacteria http://purl.obolibrary.org/obo/GO_0009609 CHEBI:140391 biolink:ChemicalSubstance (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140391 GO:0019063 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019063 GO:0019064 biolink:BiologicalProcess fusion of virus membrane with host plasma membrane Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm. VZ:987 go-plus.json viral envelope fusion|viral envelope fusion with host membrane|viral envelope fusion with host plasma membrane|viral envelope fusion with host cell membrane|viral penetration via membrane fusion|viral entry into host cell via membrane fusion with the plasma membrane|viral-cell fusion molecule activity http://purl.obolibrary.org/obo/GO_0019064 CHEBI:72840 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72840 chebi_ph7_3 CHEBI:140392 biolink:ChemicalSubstance (3R)-3-hydroxybutanoic acid oligomer go-plus.json http://purl.obolibrary.org/obo/CHEBI_140392 GO:0019061 biolink:BiologicalProcess uncoating of virus The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome. go-plus.json viral uncoating http://purl.obolibrary.org/obo/GO_0019061 CHEBI:72841 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72841 chebi_ph7_3 GO:0019062 biolink:BiologicalProcess virion attachment to host cell The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection. VZ:956 go-plus.json viral attachment to host cell|viral absorption|virion attachment to host cell surface receptor http://purl.obolibrary.org/obo/GO_0019062 CHEBI:140390 biolink:ChemicalSubstance (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140390 GO:0019060 biolink:BiologicalProcess intracellular transport of viral protein in host cell The directed movement of a viral protein within the host cell. go-plus.json intracellular transport of viral proteins in host cell|intracellular viral protein transport|viral capsid transport in host cell nucleus|nuclear viral capsid transport|intracellular transport of viral capsid in host cell|cytoplasmic viral capsid transport|intracellular viral capsid transport|viral capsid transport in host cell cytoplasm|intracellular transport of viral capsid protein in host cell http://purl.obolibrary.org/obo/GO_0019060 CHEBI:72845 biolink:ChemicalSubstance 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72845 chebi_ph7_3 CHEBI:140399 biolink:ChemicalSubstance specialised pro-resolving mediator go-plus.json http://purl.obolibrary.org/obo/CHEBI_140399 CHEBI:140395 biolink:ChemicalSubstance poly(nucleoside 5'-monophosphate) polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140395 chebi_ph7_3 GO:0034693 biolink:CellularComponent U11/U12 snRNP A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins. go-plus.json snRNP U11/U12|18S U11/U12 snRNP http://purl.obolibrary.org/obo/GO_0034693 GO:0034694 biolink:BiologicalProcess response to prostaglandin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. go-plus.json response to prostaglandin stimulus http://purl.obolibrary.org/obo/GO_0034694 GO:0034695 biolink:BiologicalProcess response to prostaglandin E Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. go-plus.json response to prostaglandin E stimulus http://purl.obolibrary.org/obo/GO_0034695 GO:0034696 biolink:BiologicalProcess response to prostaglandin F Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus. go-plus.json response to prostaglandin F stimulus http://purl.obolibrary.org/obo/GO_0034696 GO:0034697 biolink:BiologicalProcess response to prostaglandin I Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus. go-plus.json response to prostaglandin I stimulus http://purl.obolibrary.org/obo/GO_0034697 GO:0034698 biolink:BiologicalProcess response to gonadotropin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. go-plus.json response to gonadotropin stimulus http://purl.obolibrary.org/obo/GO_0034698 GO:0034699 biolink:BiologicalProcess response to luteinizing hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. go-plus.json response to luteinizing hormone stimulus http://purl.obolibrary.org/obo/GO_0034699 CHEBI:139399 biolink:ChemicalSubstance N-hexadecanoyl-O-(1-octadecanoyl-sn-glycero-3-phospho)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139399 GO:0019058 biolink:BiologicalProcess viral life cycle A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome. go-plus.json viral assembly, maturation, egress, and release|lytic viral life cycle|viral replication|viral infectious cycle http://purl.obolibrary.org/obo/GO_0019058 GO:0019059 biolink:BiologicalProcess obsolete initiation of viral infection OBSOLETE. The set of processes involved in the start of virus infection of cells. go-plus.json initiation of viral infection http://purl.obolibrary.org/obo/GO_0019059 GO:0019056 biolink:BiologicalProcess modulation by virus of host transcription Any process in which a virus modulates the frequency, rate or extent of its host's transcription. go-plus.json viral perturbation of host cell transcription|modification by virus of host transcription http://purl.obolibrary.org/obo/GO_0019056 GO:0019057 biolink:BiologicalProcess modulation by virus of host translation Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA. go-plus.json regulation of host translation by virus|regulation of host mRNA translation by virus|modulation of host translation by virus|host cell protein synthesis shutoff|viral host shutoff protein|viral perturbation of host cell mRNA translation|regulation of translation in host by virus|modification by virus of host cell mRNA translation|host cell shutoff http://purl.obolibrary.org/obo/GO_0019057 GO:0034690 biolink:CellularComponent integrin alphaD-beta2 complex An integrin complex that comprises one alphaD subunit and one beta2 subunit. go-plus.json alphaD-beta2 integrin complex|Itgad-Itgb2 complex http://purl.obolibrary.org/obo/GO_0034690 CHEBI:139396 biolink:ChemicalSubstance CDP-4-dehydro-6-deoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_139396 GO:0019054 biolink:BiologicalProcess modulation by virus of host cellular process The process in which a virus effects a change in the processes and activities of its host organism. go-plus.json regulation of cellular process in host by virus|regulation by virus of host cellular process|regulation of host cellular process by virus|modification by virus of host cellular process|modulation of cellular process in host by virus|modulation by virus of host process|viral host cell process manipulation http://purl.obolibrary.org/obo/GO_0019054 GO:0034691 biolink:CellularComponent integrin alphaE-beta7 complex An integrin complex that comprises one alphaE subunit and one beta7 subunit. go-plus.json Itgae-Itgb7 complex http://purl.obolibrary.org/obo/GO_0034691 CHEBI:139397 biolink:ChemicalSubstance N-hexadecanoyl-O-(1-octadecanoyl-2-oleoyl-sn-glycero-3-phospho)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139397 GO:0019055 biolink:BiologicalProcess modification by virus of host cell cycle regulation Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication. go-plus.json viral perturbation of cell cycle regulation http://purl.obolibrary.org/obo/GO_0019055 GO:0034692 biolink:CellularComponent E.F.G complex A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034692 CHEBI:139398 biolink:ChemicalSubstance N-acyl-O-(3-sn-phosphatidyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139398 GO:0019074 biolink:BiologicalProcess viral RNA genome packaging The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid. go-plus.json http://purl.obolibrary.org/obo/GO_0019074 CHEBI:140380 biolink:ChemicalSubstance an aldono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_140380 chebi_ph7_3 CHEBI:72850 biolink:ChemicalSubstance icosadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72850 GO:0019075 biolink:BiologicalProcess virus maturation The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release. go-plus.json bacteriophage maturation|viral maturation http://purl.obolibrary.org/obo/GO_0019075 GO:0019072 biolink:BiologicalProcess viral genome packaging The encapsulation of the viral genome within the capsid. go-plus.json http://purl.obolibrary.org/obo/GO_0019072 CHEBI:72852 biolink:ChemicalSubstance EpETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72852 CHEBI:72853 biolink:ChemicalSubstance 17(18)-EpETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72853 GO:0019073 biolink:BiologicalProcess viral DNA genome packaging The packing of viral DNA into a capsid. go-plus.json http://purl.obolibrary.org/obo/GO_0019073 GO:0019070 biolink:BiologicalProcess viral genome maturation The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes. go-plus.json http://purl.obolibrary.org/obo/GO_0019070 CHEBI:72854 biolink:ChemicalSubstance EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_72854 CHEBI:72855 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,19Z)-16,17-epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72855 GO:0019071 biolink:BiologicalProcess viral DNA cleavage involved in viral genome maturation The cleavage of viral DNA into singular functional units. go-plus.json http://purl.obolibrary.org/obo/GO_0019071 CHEBI:72857 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72857 chebi_ph7_3 CHEBI:140388 biolink:ChemicalSubstance (3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140388 CHEBI:72858 biolink:ChemicalSubstance 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72858 chebi_ph7_3 CHEBI:72859 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycerol-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72859 chebi_ph7_3 CHEBI:140384 biolink:ChemicalSubstance (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140384 chebi_ph7_3 CHEBI:140385 biolink:ChemicalSubstance (3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140385 chebi_ph7_3 CHEBI:140383 biolink:ChemicalSubstance (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140383 chebi_ph7_3 GO:0034682 biolink:CellularComponent integrin alphav-beta1 complex An integrin complex that comprises one alphav subunit and one beta1 subunit. go-plus.json alphav-beta1 integrin complex|ITGAV-ITGB1 complex http://purl.obolibrary.org/obo/GO_0034682 GO:0034683 biolink:CellularComponent integrin alphav-beta3 complex An integrin complex that comprises one alphav subunit and one beta3 subunit. go-plus.json ITGAV-ITGB3 complex|alphav-beta3 integrin complex http://purl.obolibrary.org/obo/GO_0034683 GO:0034684 biolink:CellularComponent integrin alphav-beta5 complex An integrin complex that comprises one alphav subunit and one beta5 subunit. go-plus.json alphav-beta5 integrin complex|ITGAV-ITGB5 complex http://purl.obolibrary.org/obo/GO_0034684 GO:0034685 biolink:CellularComponent integrin alphav-beta6 complex An integrin complex that comprises one alphav subunit and one beta6 subunit. go-plus.json alphav-beta6 integrin complex|ITGAV-ITGB6 complex http://purl.obolibrary.org/obo/GO_0034685 GO:0034686 biolink:CellularComponent integrin alphav-beta8 complex An integrin complex that comprises one alphav subunit and one beta8 subunit. go-plus.json ITGAV-ITGB8 complex|alphav-beta8 integrin complex http://purl.obolibrary.org/obo/GO_0034686 GO:0034687 biolink:CellularComponent integrin alphaL-beta2 complex An integrin complex that comprises one alphaL subunit and one beta2 subunit. go-plus.json alphaL-beta2 integrin complex|Itgal-Itgb2 complex http://purl.obolibrary.org/obo/GO_0034687 GO:0034688 biolink:CellularComponent integrin alphaM-beta2 complex An integrin complex that comprises one alphaM subunit and one beta2 subunit. go-plus.json alphaM-beta2 integrin complex|Itgam-Itgb2 complex http://purl.obolibrary.org/obo/GO_0034688 GO:0034689 biolink:CellularComponent integrin alphaX-beta2 complex An integrin complex that comprises one alphaX subunit and one beta2 subunit. go-plus.json alphaX-beta2 integrin complex|Itgax-Itgb2 complex http://purl.obolibrary.org/obo/GO_0034689 GO:0019069 biolink:BiologicalProcess viral capsid assembly The assembly of a virus capsid from its protein subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0019069 GO:0019067 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019067 GO:0019068 biolink:BiologicalProcess virion assembly A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed. go-plus.json virus assembly|bacteriophage assembly|phage assembly|viral particle assembly|virion organization|virion assembly and maintenance|virus particle assembly|viral assembly http://purl.obolibrary.org/obo/GO_0019068 GO:0019065 biolink:BiologicalProcess receptor-mediated endocytosis of virus by host cell Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell. go-plus.json viral receptor mediated endocytosis|receptor mediated endocytosis of virus particle by host|receptor mediated endocytosis by host of virus particle|receptor-mediated endocytosis of virus by host|virus receptor-mediated endocytosis by host|viral entry into host cell via receptor-mediated endocytosis|receptor mediated endocytosis of virus by host http://purl.obolibrary.org/obo/GO_0019065 GO:0034680 biolink:CellularComponent integrin alpha10-beta1 complex An integrin complex that comprises one alpha10 subunit and one beta1 subunit. go-plus.json ITGA10-ITGB1 complex|alpha10-beta1 integrin complex http://purl.obolibrary.org/obo/GO_0034680 GO:0034681 biolink:CellularComponent integrin alpha11-beta1 complex An integrin complex that comprises one alpha11 subunit and one beta1 subunit. go-plus.json ITGA11-ITGB1 complex|alpha11-beta1 integrin complex http://purl.obolibrary.org/obo/GO_0034681 GO:0019066 biolink:BiologicalProcess obsolete translocation of virus into host cell OBSOLETE. The translocation of an entire virus particle across the host cell plasma membrane. go-plus.json viral translocation|translocation of virus into host cell http://purl.obolibrary.org/obo/GO_0019066 GO:0020030 biolink:CellularComponent infected host cell surface knob Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species. go-plus.json http://purl.obolibrary.org/obo/GO_0020030 GO:0019041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019041 GO:0019042 biolink:BiologicalProcess viral latency The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate. go-plus.json phage lysogeny|viral dormancy|latent virus infection http://purl.obolibrary.org/obo/GO_0019042 GO:0020031 biolink:CellularComponent polar ring of apical complex An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite. go-plus.json anterior polar ring of apical complex|upper polar ring of apical complex http://purl.obolibrary.org/obo/GO_0020031 GO:0020032 biolink:CellularComponent basal ring of apical complex An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite. go-plus.json preconoidal ring of apical complex|posterior polar ring of apical complex|lower polar ring of apical complex http://purl.obolibrary.org/obo/GO_0020032 GO:0020033 biolink:BiologicalProcess antigenic variation Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system. Wikipedia:Antigenic_variation go-plus.json surface antigen variation http://purl.obolibrary.org/obo/GO_0020033 CHEBI:72864 biolink:ChemicalSubstance 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72864 chebi_ph7_3 GO:0019040 biolink:MolecularActivity obsolete viral host shutoff protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json viral host shutoff protein http://purl.obolibrary.org/obo/GO_0019040 GO:0020034 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0020034 CHEBI:72865 biolink:ChemicalSubstance (5Z,8Z,11Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72865 GO:0020035 biolink:BiologicalProcess cytoadherence to microvasculature, mediated by symbiont protein The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte. go-plus.json parasite-protein-mediated cytoadherence to microvasculature|cytoadherence to microvasculature, mediated by parasite protein|symbiont-protein-mediated cytoadherence to microvasculature|heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein http://purl.obolibrary.org/obo/GO_0020035 GO:0020036 biolink:CellularComponent Maurer's cleft A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton. go-plus.json Maurers cleft http://purl.obolibrary.org/obo/GO_0020036 GO:0020037 biolink:MolecularActivity heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. go-plus.json haem binding http://purl.obolibrary.org/obo/GO_0020037 CHEBI:72868 biolink:ChemicalSubstance dihydroxyicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72868 GO:0034679 biolink:CellularComponent integrin alpha9-beta1 complex An integrin complex that comprises one alpha9 subunit and one beta1 subunit. go-plus.json alpha9-beta1 integrin complex|ITGA9-ITGB1 complex http://purl.obolibrary.org/obo/GO_0034679 CHEBI:140377 biolink:ChemicalSubstance (2S)-flavan-4-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_140377 chebi_ph7_3 CHEBI:140374 biolink:ChemicalSubstance 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate(13-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140374 chebi_ph7_3 CHEBI:140371 biolink:ChemicalSubstance N(4)-[6-phospho-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-glycan]-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140371 chebi_ph7_3 CHEBI:140372 biolink:ChemicalSubstance 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate(13-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140372 chebi_ph7_3 GO:0034671 biolink:BiologicalProcess retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros. go-plus.json retinoic acid receptor signalling pathway involved in pronephros anterior-posterior patterning|retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification http://purl.obolibrary.org/obo/GO_0034671 GO:0034672 biolink:BiologicalProcess anterior/posterior pattern specification involved in pronephros development The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. go-plus.json anterior/posterior pattern specification involved in pronephric kidney development http://purl.obolibrary.org/obo/GO_0034672 GO:0034673 biolink:CellularComponent inhibin-betaglycan-ActRII complex A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B. go-plus.json http://purl.obolibrary.org/obo/GO_0034673 GO:0034674 biolink:CellularComponent integrin alpha5-beta1 complex An integrin complex that comprises one alpha5 subunit and one beta1 subunit. go-plus.json ITGA5-ITGB1 complex|VLA-5 complex|alpha5-beta1 integrin complex http://purl.obolibrary.org/obo/GO_0034674 GO:0034675 biolink:CellularComponent integrin alpha6-beta1 complex An integrin complex that comprises one alpha6 subunit and one beta1 subunit. go-plus.json ITGA6-ITGB1 complex|alpha6-beta1 integrin complex|VLA-6 complex http://purl.obolibrary.org/obo/GO_0034675 GO:0034676 biolink:CellularComponent integrin alpha6-beta4 complex An integrin complex that comprises one alpha6 subunit and one beta4 subunit. go-plus.json ITGA6-ITGB4 complex|alpha6-beta4 integrin complex http://purl.obolibrary.org/obo/GO_0034676 GO:0034677 biolink:CellularComponent integrin alpha7-beta1 complex An integrin complex that comprises one alpha7 subunit and one beta1 subunit. go-plus.json ITGA7-ITGB1 complex|alpha7-beta1 integrin complex http://purl.obolibrary.org/obo/GO_0034677 CHEBI:140379 biolink:ChemicalSubstance an aldopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_140379 chebi_ph7_3 GO:0034678 biolink:CellularComponent integrin alpha8-beta1 complex An integrin complex that comprises one alpha8 subunit and one beta1 subunit. go-plus.json ITGA8-ITGB1 complex|alpha8-beta1 integrin complex http://purl.obolibrary.org/obo/GO_0034678 GO:0019038 biolink:CellularComponent obsolete provirus OBSOLETE. The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle. Wikipedia:Provirus go-plus.json http://purl.obolibrary.org/obo/GO_0019038 GO:0020038 biolink:CellularComponent subpellicular network A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0020038 GO:0020039 biolink:CellularComponent pellicle The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles. go-plus.json http://purl.obolibrary.org/obo/GO_0020039 GO:0019039 biolink:MolecularActivity obsolete viral-cell fusion molecule activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json viral-cell fusion molecule activity http://purl.obolibrary.org/obo/GO_0019039 GO:0019036 biolink:CellularComponent viral transcriptional complex Specific locations and structures in the virus infected cell involved in transcribing the viral genome. go-plus.json http://purl.obolibrary.org/obo/GO_0019036 GO:0019037 biolink:CellularComponent viral assembly intermediate Specific locations and structures in the virus infected cell involved in assembling new virions. go-plus.json http://purl.obolibrary.org/obo/GO_0019037 GO:0019034 biolink:CellularComponent viral replication complex Specific locations and structures in the virus infected cell involved in replicating the viral genome. go-plus.json http://purl.obolibrary.org/obo/GO_0019034 GO:0019035 biolink:CellularComponent viral integration complex A nucleoprotein complex containing viral genetic material and the viral integrase, required for genome integration into the host's genome. May contain other proteins. Wikipedia:Pre-integration_complex go-plus.json PIC|pre-integration complex http://purl.obolibrary.org/obo/GO_0019035 GO:0019032 biolink:CellularComponent obsolete viral glycoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json viral glycoprotein http://purl.obolibrary.org/obo/GO_0019032 CHEBI:139375 biolink:ChemicalSubstance (R)-2-hydroxyhexadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139375 GO:0019033 biolink:CellularComponent viral tegument A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically. Wikipedia:Viral_tegument go-plus.json http://purl.obolibrary.org/obo/GO_0019033 GO:0034670 biolink:BiologicalProcess chemotaxis to arachidonic acid The directed movement of a motile cell or organism in response to the presence of arachidonic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0034670 CHEBI:139376 biolink:ChemicalSubstance 2-hydroxy-3-methyldodecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139376 CHEBI:72860 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72860 chebi_ph7_3 GO:0019052 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019052 GO:0019053 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019053 GO:0020020 biolink:CellularComponent food vacuole Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa. go-plus.json digestive vacuole http://purl.obolibrary.org/obo/GO_0020020 CHEBI:139392 biolink:ChemicalSubstance 3-methyldodecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139392 GO:0020021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0020021 GO:0019050 biolink:BiologicalProcess suppression by virus of host apoptotic process Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication. go-plus.json suppression by virus of host apoptosis|negative regulation by virus of host apoptosis|negative regulation of apoptosis by virus|suppression of apoptosis in host by virus http://purl.obolibrary.org/obo/GO_0019050 GO:0020022 biolink:CellularComponent acidocalcisome An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. go-plus.json volutin granule|metachromatic granule|polyphosphate vacuole http://purl.obolibrary.org/obo/GO_0020022 goslim_pir GO:0019051 biolink:BiologicalProcess induction by virus of host apoptotic process The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions. go-plus.json activation by virus of host apoptosis|activation by virus of host apoptotic programmed cell death|activation of apoptosis in host by virus|induction by virus of host apoptosis|induction by virus of host apoptotic programmed cell death|induction of apoptosis in host by virus http://purl.obolibrary.org/obo/GO_0019051 CHEBI:139394 biolink:ChemicalSubstance alpha-D-galactosyl ditrans,octacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139394 GO:0020023 biolink:CellularComponent kinetoplast A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum. Wikipedia:Kinetoplast go-plus.json http://purl.obolibrary.org/obo/GO_0020023 GO:0020025 biolink:CellularComponent subpellicular microtubule Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid. go-plus.json http://purl.obolibrary.org/obo/GO_0020025 GO:0020026 biolink:CellularComponent merozoite dense granule Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell. go-plus.json dense body http://purl.obolibrary.org/obo/GO_0020026 GO:0034668 biolink:CellularComponent integrin alpha4-beta1 complex An integrin complex that comprises one alpha4 subunit and one beta1 subunit. go-plus.json alpha4-beta1 integrin complex|VLA-4 complex|ITGA4-ITGB1 complex http://purl.obolibrary.org/obo/GO_0034668 GO:0034669 biolink:CellularComponent integrin alpha4-beta7 complex An integrin complex that comprises one alpha4 subunit and one beta7 subunit. go-plus.json ITGA4-ITGB7 complex|alpha4-beta7 integrin complex http://purl.obolibrary.org/obo/GO_0034669 GO:0034660 biolink:BiologicalProcess ncRNA metabolic process The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs). go-plus.json ncRNA metabolism http://purl.obolibrary.org/obo/GO_0034660 GO:0034661 biolink:BiologicalProcess ncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs). go-plus.json ncRNA breakdown|ncRNA catabolism|ncRNA degradation http://purl.obolibrary.org/obo/GO_0034661 GO:0034662 biolink:CellularComponent CFTR-NHERF-ezrin complex A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_0034662 GO:0034663 biolink:CellularComponent endoplasmic reticulum chaperone complex A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1. go-plus.json endoplasmic reticulum network complex|ER network complex|ER chaperone complex http://purl.obolibrary.org/obo/GO_0034663 GO:0034664 biolink:CellularComponent Ig heavy chain-bound endoplasmic reticulum chaperone complex A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1. go-plus.json Ig heavy chain-bound ER chaperone complex|immunoglobulin heavy chain-bound endoplasmic reticulum chaperone complex http://purl.obolibrary.org/obo/GO_0034664 GO:0034665 biolink:CellularComponent integrin alpha1-beta1 complex An integrin complex that comprises one alpha1 subunit and one beta1 subunit. go-plus.json alpha1-beta1 integrin complex|VLA-1 complex|ITGA1-ITGB1 complex http://purl.obolibrary.org/obo/GO_0034665 GO:0034666 biolink:CellularComponent integrin alpha2-beta1 complex An integrin complex that comprises one alpha2 subunit and one beta1 subunit. go-plus.json ITGA2-ITGB1 complex|VLA-2 complex http://purl.obolibrary.org/obo/GO_0034666 CHEBI:140369 biolink:ChemicalSubstance N(4)-[6-(N-acetyl-alpha-D-glucosaminyl-1-phospho)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-glycan]-L-asparagine residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140369 chebi_ph7_3 GO:0034667 biolink:CellularComponent integrin alpha3-beta1 complex An integrin complex that comprises one alpha3 subunit and one beta1 subunit. go-plus.json ITGA3-ITGB1 complex|alpha3-beta1 integrin complex|VLA-3 complex http://purl.obolibrary.org/obo/GO_0034667 GO:0019049 biolink:BiologicalProcess mitigation of host defenses by virus A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json evasion of host defenses by virus|viral host defence evasion|evasion or tolerance of host defenses by virus|viral host defense evasion http://purl.obolibrary.org/obo/GO_0019049 GO:0020027 biolink:BiologicalProcess hemoglobin metabolic process The chemical reactions and pathways involving hemoglobin, including its uptake and utilization. go-plus.json haemoglobin metabolism|haemoglobin metabolic process|hemoglobin metabolism http://purl.obolibrary.org/obo/GO_0020027 GO:0020028 biolink:BiologicalProcess endocytic hemoglobin import into cell The directed movement of hemoglobin into a cell by receptor-mediated endocytosis. go-plus.json endocytic hemoglobin import|hemoglobin uptake|haemoglobin uptake http://purl.obolibrary.org/obo/GO_0020028 GO:0020029 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0020029 GO:0019047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019047 GO:0019048 biolink:BiologicalProcess modulation by virus of host process The process in which a virus effects a change in the structure or processes of its host organism. VZ:886 go-plus.json modulation by virus of host morphology or physiology|viral-host process|modulation by virus of host anatomy or process|disruption by virus of host cell|host-virus interaction|virus-host process|viral interaction with host|modulation by virus of host anatomical structure or process|virus-host interaction http://purl.obolibrary.org/obo/GO_0019048 GO:0019045 biolink:BiologicalProcess latent virus replication Any process required for latent viral replication in a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0019045 GO:0019046 biolink:BiologicalProcess release from viral latency The process by which a virus begins to replicate following a latency replication decision (switch). go-plus.json http://purl.obolibrary.org/obo/GO_0019046 GO:0019043 biolink:BiologicalProcess establishment of viral latency A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects. go-plus.json lysogenic commitment|phage lysogeny http://purl.obolibrary.org/obo/GO_0019043 GO:0019044 biolink:BiologicalProcess maintenance of viral latency The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms. go-plus.json prophage maintenance|provirus maintenance|latent virus maintenance http://purl.obolibrary.org/obo/GO_0019044 GO:0019020 biolink:CellularComponent obsolete multipartite viral genome OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion. go-plus.json http://purl.obolibrary.org/obo/GO_0019020 GO:0020010 biolink:CellularComponent conoid A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0020010 GO:0020011 biolink:CellularComponent apicoplast The plastid organelle found in apicomplexans. Wikipedia:Apicoplast go-plus.json http://purl.obolibrary.org/obo/GO_0020011 GO:0020012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0020012 GO:0020013 biolink:BiologicalProcess modulation by symbiont of host erythrocyte aggregation Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes. Wikipedia:Rosetting go-plus.json rosetting http://purl.obolibrary.org/obo/GO_0020013 GO:0020014 biolink:BiologicalProcess schizogony Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously. Wikipedia:Protozoal_merogony go-plus.json http://purl.obolibrary.org/obo/GO_0020014 GO:0020015 biolink:CellularComponent glycosome A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis. Wikipedia:Glycosome go-plus.json http://purl.obolibrary.org/obo/GO_0020015 goslim_pir GO:0034657 biolink:CellularComponent GID complex A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p. go-plus.json http://purl.obolibrary.org/obo/GO_0034657 CHEBI:82207 biolink:ChemicalSubstance (4S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_82207 chebi_ph7_3 GO:0034658 biolink:MolecularActivity isopropylmalate transmembrane transporter activity Enables the transfer of isopropylmalate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0034658 CHEBI:140356 biolink:ChemicalSubstance 7-methoxyisoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_140356 chebi_ph7_3 GO:0010688 biolink:BiologicalProcess negative regulation of ribosomal protein gene transcription by RNA polymerase II Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. go-plus.json negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0010688 CHEBI:82204 biolink:ChemicalSubstance (4R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_82204 chebi_ph7_3 GO:0034659 biolink:BiologicalProcess isopropylmalate transport The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0034659 CHEBI:140353 biolink:ChemicalSubstance phosphatidic acid 40:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_140353 GO:0010689 biolink:BiologicalProcess negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010689 CHEBI:140354 biolink:ChemicalSubstance phosphatidic acid 38:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_140354 GO:0009693 biolink:BiologicalProcess ethylene biosynthetic process The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. MetaCyc:ETHYL-PWY go-plus.json ethylene biosynthesis from L-methionine|ethylene biosynthetic process from L-methionine|ethene biosynthetic process|ethene biosynthesis|ethylene anabolism|ethene biosynthetic process from L-methionine|ethene biosynthesis from L-methionine|ethylene synthesis|ethylene formation|ethylene biosynthesis http://purl.obolibrary.org/obo/GO_0009693 GO:0010682 biolink:BiologicalProcess obsolete cinnamic acid biosynthetic process involved in flavonoid metabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids. go-plus.json http://purl.obolibrary.org/obo/GO_0010682 GO:0010683 biolink:BiologicalProcess tricyclic triterpenoid metabolic process The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings. go-plus.json tricyclic triterpenoid metabolism http://purl.obolibrary.org/obo/GO_0010683 GO:0009694 biolink:BiologicalProcess jasmonic acid metabolic process The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid. go-plus.json jasmonic acid metabolism http://purl.obolibrary.org/obo/GO_0009694 GO:0034650 biolink:BiologicalProcess cortisol metabolic process The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. go-plus.json cortisol metabolism http://purl.obolibrary.org/obo/GO_0034650 GO:0034651 biolink:BiologicalProcess cortisol biosynthetic process The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. go-plus.json cortisol formation|cortisol biosynthesis|cortisol anabolism|cortisol synthesis http://purl.obolibrary.org/obo/GO_0034651 GO:0009695 biolink:BiologicalProcess jasmonic acid biosynthetic process The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative. MetaCyc:PWY-735 go-plus.json jasmonic acid biosynthesis|jasmonic acid anabolism|jasmonic acid synthesis|jasmonic acid formation http://purl.obolibrary.org/obo/GO_0009695 GO:0010680 biolink:BiologicalProcess obsolete cinnamic acid biosynthetic process involved in coumarin metabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin. go-plus.json http://purl.obolibrary.org/obo/GO_0010680 GO:0034652 biolink:BiologicalProcess extrachromosomal circular DNA localization involved in cell aging A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging. go-plus.json extrachromosomal circular DNA localization during cell ageing|extrachromosomal circular DNA localization during cell aging|extrachromosomal circular DNA localisation involved in cell aging http://purl.obolibrary.org/obo/GO_0034652 GO:0009696 biolink:BiologicalProcess salicylic acid metabolic process The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. go-plus.json salicylic acid metabolism http://purl.obolibrary.org/obo/GO_0009696 GO:0010681 biolink:BiologicalProcess obsolete cinnamic acid biosynthetic process involved in stilbene metabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene. go-plus.json http://purl.obolibrary.org/obo/GO_0010681 GO:0010686 biolink:BiologicalProcess tetracyclic triterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings. go-plus.json tetracyclic triterpenoid biosynthesis http://purl.obolibrary.org/obo/GO_0010686 GO:0034653 biolink:BiologicalProcess retinoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A. go-plus.json retinoic acid degradation|vitamin A1 acid catabolic process|retinoic acid breakdown|retinoic acid catabolism http://purl.obolibrary.org/obo/GO_0034653 GO:0009697 biolink:BiologicalProcess salicylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. MetaCyc:PWY-981 go-plus.json salicylic acid biosynthesis|salicylic acid anabolism|salicylic acid synthesis|salicylic acid formation|salicylate biosynthetic process http://purl.obolibrary.org/obo/GO_0009697 CHEBI:140359 biolink:ChemicalSubstance UDP-monosaccharide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140359 chebi_ph7_3 GO:0034654 biolink:BiologicalProcess nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. go-plus.json nucleobase, nucleoside, nucleotide and nucleic acid synthesis|nucleobase, nucleoside, nucleotide and nucleic acid anabolism|nucleobase, nucleoside, nucleotide and nucleic acid formation|nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis http://purl.obolibrary.org/obo/GO_0034654 GO:0010687 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010687 GO:0009698 biolink:BiologicalProcess phenylpropanoid metabolic process The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid. MetaCyc:PWY1F-467 go-plus.json phenylpropanoid metabolism http://purl.obolibrary.org/obo/GO_0009698 GO:0009699 biolink:BiologicalProcess phenylpropanoid biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid. go-plus.json phenylpropanoid anabolism|phenylpropanoid synthesis|phenylpropanoid formation|phenylpropanoid biosynthesis http://purl.obolibrary.org/obo/GO_0009699 GO:0010684 biolink:BiologicalProcess tricyclic triterpenoid catabolic process The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings. go-plus.json tricyclic triterpenoid catabolism http://purl.obolibrary.org/obo/GO_0010684 GO:0019018 biolink:CellularComponent obsolete bipartite viral genome OBSOLETE. A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion. go-plus.json http://purl.obolibrary.org/obo/GO_0019018 GO:0034655 biolink:BiologicalProcess nucleobase-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids. go-plus.json nucleobase, nucleoside, nucleotide and nucleic acid catabolic process|nucleobase, nucleoside, nucleotide and nucleic acid breakdown|nucleobase, nucleoside, nucleotide and nucleic acid catabolism|nucleobase, nucleoside, nucleotide and nucleic acid degradation http://purl.obolibrary.org/obo/GO_0034655 goslim_generic|goslim_chembl CHEBI:140357 biolink:ChemicalSubstance N(4)-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-glycan]-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140357 chebi_ph7_3 GO:0034656 biolink:BiologicalProcess nucleobase-containing small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. go-plus.json nucleobase, nucleoside and nucleotide catabolism|nucleobase, nucleoside and nucleotide degradation|nucleobase, nucleoside and nucleotide breakdown http://purl.obolibrary.org/obo/GO_0034656 CHEBI:140358 biolink:ChemicalSubstance monosaccharide 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140358 chebi_ph7_3 GO:0010685 biolink:BiologicalProcess tetracyclic triterpenoid metabolic process The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings. go-plus.json tetracyclic triterpenoid metabolism http://purl.obolibrary.org/obo/GO_0010685 GO:0019019 biolink:CellularComponent obsolete tripartite viral genome OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion. go-plus.json http://purl.obolibrary.org/obo/GO_0019019 GO:0020016 biolink:CellularComponent ciliary pocket Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes. go-plus.json flagellar pocket|cilial pocket|cilium pocket http://purl.obolibrary.org/obo/GO_0020016 GO:0019016 biolink:CellularComponent obsolete non-segmented viral genome OBSOLETE. A viral genome that consists of one continuous nucleic acid molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019016 GO:0019017 biolink:CellularComponent obsolete segmented viral genome OBSOLETE. A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion. go-plus.json http://purl.obolibrary.org/obo/GO_0019017 GO:0020017 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0020017 GO:0020018 biolink:CellularComponent ciliary pocket membrane That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket). go-plus.json cilium pocket membrane|cilial pocket membrane|flagellar pocket membrane http://purl.obolibrary.org/obo/GO_0020018 GO:0019014 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019014 GO:0019015 biolink:CellularComponent obsolete viral genome OBSOLETE. The whole of the genetic information of a virus, contained as either DNA or RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0019015 GO:0019012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019012 GO:0019013 biolink:CellularComponent viral nucleocapsid The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle. go-plus.json nucleocapsid|core http://purl.obolibrary.org/obo/GO_0019013 goslim_chembl GO:0019010 biolink:MolecularActivity farnesoic acid O-methyltransferase activity Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine. go-plus.json S-adenosyl-methionine:farnesoic acid O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0019010 GO:0019011 biolink:MolecularActivity obsolete DNA replication accessory factor OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA replication accessory factor http://purl.obolibrary.org/obo/GO_0019011 GO:0019030 biolink:CellularComponent icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure. go-plus.json quasispherical viral capsid http://purl.obolibrary.org/obo/GO_0019030 GO:0019031 biolink:CellularComponent viral envelope The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins. Wikipedia:Viral_envelope go-plus.json viral outside membrane|viral glycoprotein http://purl.obolibrary.org/obo/GO_0019031 goslim_chembl CHEBI:139371 biolink:ChemicalSubstance aryl sulfate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139371 chebi_ph7_3 CHEBI:72896 biolink:ChemicalSubstance cardiolipin 72:4(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72896 chebi_ph7_3 CHEBI:139372 biolink:ChemicalSubstance 3-methylnonanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139372 GO:0020002 biolink:CellularComponent host cell plasma membrane The plasma membrane surrounding a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0020002 CHEBI:72899 biolink:ChemicalSubstance cardiolipin 72:7(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72899 chebi_ph7_3 GO:0020003 biolink:CellularComponent symbiont-containing vacuole Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont. go-plus.json pathogen-occupied vacuole|SCV|Salmonella-containing vacuole|parasitophorous vacuole|bacterium-containing vacuole http://purl.obolibrary.org/obo/GO_0020003 GO:0020004 biolink:CellularComponent symbiont-containing vacuolar space The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane. go-plus.json symbiont-containing vacuole space|parasitophorous vacuolar space http://purl.obolibrary.org/obo/GO_0020004 GO:0034646 biolink:CellularComponent organelle-enclosing lipid monolayer A lipid monolayer that surrounds and encloses an organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0034646 GO:0034647 biolink:MolecularActivity histone H3-tri/di/monomethyl-lysine-4 demethylase activity Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. RHEA:60208|EC:1.14.11.67 go-plus.json histone demethylase activity (H3-K4-me3 specific)|H3K4me3 demethylase activity|histone H3-K4me3 demethylase activity|histone H3K4me2 demethylase activity|histone H3-K4me2 demethylase activity|histone demethylase activity (H3-trimethyl-K4 specific) http://purl.obolibrary.org/obo/GO_0034647 CHEBI:140345 biolink:ChemicalSubstance hydroxy polyunsaturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140345 GO:0010699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010699 GO:0034648 biolink:MolecularActivity obsolete histone demethylase activity (H3-dimethyl-K4 specific) OBSOLETE. Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein. go-plus.json histone demethylase activity (H3-K4-me2 specific) http://purl.obolibrary.org/obo/GO_0034648 GO:0034649 biolink:MolecularActivity obsolete histone demethylase activity (H3-monomethyl-K4 specific) OBSOLETE. Catalysis of the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein. go-plus.json histone demethylase activity (H3-K4-me1 specific) http://purl.obolibrary.org/obo/GO_0034649 GO:0010693 biolink:BiologicalProcess negative regulation of alkaline phosphatase activity Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. go-plus.json http://purl.obolibrary.org/obo/GO_0010693 GO:0010694 biolink:BiologicalProcess positive regulation of alkaline phosphatase activity Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. go-plus.json http://purl.obolibrary.org/obo/GO_0010694 GO:0034640 biolink:BiologicalProcess establishment of mitochondrion localization by microtubule attachment The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization. go-plus.json mitochondrial migration by microtubule attachment|mitochondrial localization by microtubule attachment|mitochondrion migration by microtubule attachment|establishment of mitochondrion localisation by microtubule attachment http://purl.obolibrary.org/obo/GO_0034640 GO:0010691 biolink:BiologicalProcess negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. go-plus.json http://purl.obolibrary.org/obo/GO_0010691 GO:0034641 biolink:BiologicalProcess cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. go-plus.json cellular nitrogen compound metabolism http://purl.obolibrary.org/obo/GO_0034641 goslim_chembl|goslim_generic GO:0010692 biolink:BiologicalProcess regulation of alkaline phosphatase activity Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. go-plus.json http://purl.obolibrary.org/obo/GO_0010692 GO:0010697 biolink:BiologicalProcess negative regulation of mitotic spindle pole body separation Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. go-plus.json negative regulation of SPB separation http://purl.obolibrary.org/obo/GO_0010697 GO:0034642 biolink:BiologicalProcess mitochondrion migration along actin filament The directed movement of a mitochondrion along a microfilament, mediated by motor proteins. go-plus.json mitochondrial migration along actin filament|mitochondrial migration, actin-mediated|mitochondrial migration along microfilament|mitochondrion migration along microfilament|mitochondrion transport along actin filament http://purl.obolibrary.org/obo/GO_0034642 GO:0010698 biolink:MolecularActivity acetyltransferase activator activity Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule. go-plus.json acetyltransferase stimulator activity http://purl.obolibrary.org/obo/GO_0010698 GO:0034643 biolink:BiologicalProcess establishment of mitochondrion localization, microtubule-mediated The directed movement of the mitochondrion to a specific location, by a process involving microtubules. go-plus.json microtubule-mediated mitochondrion localization|mitochondrial localization, microtubule-mediated|establishment of mitochondrion localisation, microtubule-mediated http://purl.obolibrary.org/obo/GO_0034643 GO:0019029 biolink:CellularComponent helical viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure. go-plus.json http://purl.obolibrary.org/obo/GO_0019029 GO:0034644 biolink:BiologicalProcess cellular response to UV Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. go-plus.json cellular response to ultraviolet light stimulus|cellular response to ultraviolet radiation stimulus|cellular response to UV light stimulus|cellular response to UV radiation stimulus http://purl.obolibrary.org/obo/GO_0034644 GO:0010695 biolink:BiologicalProcess regulation of mitotic spindle pole body separation Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. go-plus.json regulation of SPB separation http://purl.obolibrary.org/obo/GO_0010695 GO:0010696 biolink:BiologicalProcess positive regulation of mitotic spindle pole body separation Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. go-plus.json positive regulation of SPB separation http://purl.obolibrary.org/obo/GO_0010696 GO:0034645 biolink:BiologicalProcess cellular macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. go-plus.json cellular macromolecule anabolism|cellular biopolymer biosynthetic process|cellular macromolecule biosynthesis|cellular macromolecule synthesis|cellular macromolecule formation http://purl.obolibrary.org/obo/GO_0034645 CHEBI:140347 biolink:ChemicalSubstance substituted beta-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140347 chebi_ph7_3 GO:0020005 biolink:CellularComponent symbiont-containing vacuole membrane The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont. go-plus.json parasitophorous vacuolar membrane http://purl.obolibrary.org/obo/GO_0020005 GO:0019027 biolink:CellularComponent obsolete ambisense viral genome OBSOLETE. A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019027 GO:0020006 biolink:CellularComponent symbiont-containing vacuolar membrane network Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm. go-plus.json tubulovesicular network|symbiont-containing vacuole membrane network|parasitophorous vacuolar membrane network http://purl.obolibrary.org/obo/GO_0020006 GO:0019028 biolink:CellularComponent viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres. Wikipedia:Capsid go-plus.json http://purl.obolibrary.org/obo/GO_0019028 goslim_chembl GO:0019025 biolink:CellularComponent obsolete positive sense viral genome OBSOLETE. A single stranded RNA genome with the same nucleotide polarity as mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0019025 GO:0020007 biolink:CellularComponent apical complex A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0020007 GO:0020008 biolink:CellularComponent rhoptry A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole. Wikipedia:Rhoptry go-plus.json paired organelles|toxoneme http://purl.obolibrary.org/obo/GO_0020008 GO:0019026 biolink:CellularComponent obsolete negative sense viral genome OBSOLETE. A single stranded RNA genome with the opposite nucleotide polarity as mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0019026 GO:0019023 biolink:CellularComponent obsolete dsRNA viral genome OBSOLETE. A viral genome composed of double stranded RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0019023 GO:0020009 biolink:CellularComponent microneme A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell. Wikipedia:Microneme go-plus.json sarconeme http://purl.obolibrary.org/obo/GO_0020009 CHEBI:139362 biolink:ChemicalSubstance 2-hydroxy-3-methylundecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139362 GO:0010690 biolink:BiologicalProcess negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0010690 GO:0019024 biolink:CellularComponent obsolete ssRNA viral genome OBSOLETE. A viral genome composed of single stranded RNA of either positive or negative sense. go-plus.json http://purl.obolibrary.org/obo/GO_0019024 CHEBI:139363 biolink:ChemicalSubstance 2-hydroxy-3-methylnonanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139363 GO:0019021 biolink:CellularComponent obsolete DNA viral genome OBSOLETE. A viral genome composed of deoxyribonucleic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0019021 CHEBI:72892 biolink:ChemicalSubstance cardiolipin 70:6(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72892 chebi_ph7_3 GO:0019022 biolink:CellularComponent obsolete RNA viral genome OBSOLETE. A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked. go-plus.json http://purl.obolibrary.org/obo/GO_0019022 GO:0034635 biolink:BiologicalProcess glutathione transport The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0034635 GO:0010668 biolink:BiologicalProcess ectodermal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010668 GO:0034636 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034636 GO:0010669 biolink:BiologicalProcess epithelial structure maintenance A tissue homeostatic process required for the maintenance of epithelial structure. go-plus.json http://purl.obolibrary.org/obo/GO_0010669 GO:0034637 biolink:BiologicalProcess cellular carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0034637 GO:0010666 biolink:BiologicalProcess positive regulation of cardiac muscle cell apoptotic process Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. go-plus.json positive regulation of cardiac muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010666 CHEBI:140331 biolink:ChemicalSubstance 4'-hydroxyflavanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_140331 chebi_ph7_3 GO:0034638 biolink:BiologicalProcess phosphatidylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. go-plus.json phosphatidylcholine breakdown|phosphatidylcholine catabolism|phosphatidylcholine degradation http://purl.obolibrary.org/obo/GO_0034638 GO:0010667 biolink:BiologicalProcess negative regulation of cardiac muscle cell apoptotic process Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. go-plus.json down regulation of cardiac muscle cell apoptosis|downregulation of cardiac muscle cell apoptosis|down-regulation of cardiac muscle cell apoptosis|negative regulation of cardiac muscle cell apoptosis|inhibition of cardiac muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010667 CHEBI:140332 biolink:ChemicalSubstance 4'-methoxyflavanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_140332 chebi_ph7_3 GO:0034639 biolink:MolecularActivity L-amino acid efflux transmembrane transporter activity Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane. go-plus.json L-amino acid export transporter activity|L-amino acid efflux permease activity http://purl.obolibrary.org/obo/GO_0034639 CHEBI:140330 biolink:ChemicalSubstance (13R)-13-dihydrocarminomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140330 chebi_ph7_3 GO:0009680 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009680 GO:0009681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009681 GO:0010660 biolink:BiologicalProcess regulation of muscle cell apoptotic process Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. go-plus.json regulation of muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010660 GO:0009671 biolink:MolecularActivity nitrate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in). go-plus.json nitrate:hydrogen symporter activity|nitrate(chlorate):hydrogen symporter activity|nitrate(chlorate):proton symporter activity http://purl.obolibrary.org/obo/GO_0009671 GO:0010661 biolink:BiologicalProcess positive regulation of muscle cell apoptotic process Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. go-plus.json positive regulation of muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010661 GO:0009672 biolink:MolecularActivity auxin:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in). go-plus.json auxin:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0009672 GO:0009673 biolink:MolecularActivity low-affinity phosphate transmembrane transporter activity Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity phosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0009673 GO:0034630 biolink:BiologicalProcess RITS complex localization Any process in which a RITS complex is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of RITS complex localization|RITS complex localisation http://purl.obolibrary.org/obo/GO_0034630 GO:0009674 biolink:MolecularActivity potassium:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in). go-plus.json high affinity potassium transporter http://purl.obolibrary.org/obo/GO_0009674 GO:0009675 biolink:MolecularActivity high-affinity sulfate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity sulfate:hydrogen symporter activity|high affinity sulfate:proton symporter activity|high affinity sulphate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0009675 GO:0010664 biolink:BiologicalProcess negative regulation of striated muscle cell apoptotic process Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. go-plus.json down-regulation of striated muscle cell apoptosis|negative regulation of striated muscle cell apoptosis|downregulation of striated muscle cell apoptosis|down regulation of striated muscle cell apoptosis|inhibition of striated muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010664 GO:0034631 biolink:BiologicalProcess microtubule anchoring at spindle pole body Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end. go-plus.json microtubule anchoring at SPB|attachment of spindle microtubules to spindle pole body|attachment of spindle microtubules to SPB http://purl.obolibrary.org/obo/GO_0034631 CHEBI:139337 biolink:ChemicalSubstance (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_139337 chebi_ph7_3 GO:0009676 biolink:MolecularActivity low-affinity sulfate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity sulphate:hydrogen symporter activity|low affinity sulfate:hydrogen symporter activity|low affinity sulfate:proton symporter activity http://purl.obolibrary.org/obo/GO_0009676 GO:0034632 biolink:MolecularActivity retinol transmembrane transporter activity Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Reactome:R-HSA-1467466|Reactome:R-HSA-2466749|Reactome:R-HSA-2466802 go-plus.json vitamin A1 transporter activity|retinol transporter activity http://purl.obolibrary.org/obo/GO_0034632 CHEBI:139338 biolink:ChemicalSubstance EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_139338 GO:0010665 biolink:BiologicalProcess regulation of cardiac muscle cell apoptotic process Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. go-plus.json regulation of cardiac muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010665 CHEBI:139339 biolink:ChemicalSubstance EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_139339 GO:0034633 biolink:BiologicalProcess retinol transport The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. go-plus.json vitamin A1 transport http://purl.obolibrary.org/obo/GO_0034633 GO:0010662 biolink:BiologicalProcess regulation of striated muscle cell apoptotic process Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. go-plus.json regulation of striated muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010662 GO:0009677 biolink:BiologicalProcess double fertilization forming two zygotes Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis. go-plus.json http://purl.obolibrary.org/obo/GO_0009677 CHEBI:140335 biolink:ChemicalSubstance glucuronoxylan D-glucuronate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140335 chebi_ph7_3 GO:0009678 biolink:MolecularActivity pyrophosphate hydrolysis-driven proton transmembrane transporter activity Enables the transmembrane transport of one proton (H+), driven by the hydrolysis of pyrophosphate, and generating a proton motive force. TC:3.A.10|MetaCyc:TRANS-RXN-370|RHEA:13973|EC:7.1.3.1 go-plus.json proton-pumping diphosphatase|proton-pumping pyrophosphatase|proton-translocating pyrophosphatase activity|PP(i) hydrolysis-driven proton transmembrane transporter activity|H(+)-exporting diphosphatase|hydrogen-translocating pyrophosphatase activity|diphosphate hydrolysis-driven proton transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0009678 GO:0034634 biolink:MolecularActivity glutathione transmembrane transporter activity Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0034634 GO:0010663 biolink:BiologicalProcess positive regulation of striated muscle cell apoptotic process Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. go-plus.json positive regulation of striated muscle cell apoptosis http://purl.obolibrary.org/obo/GO_0010663 CHEBI:140336 biolink:ChemicalSubstance glucuronoxylan 4-O-methyl-D-glucuronate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_140336 chebi_ph7_3 GO:0009679 biolink:MolecularActivity hexose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in). go-plus.json hexose:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0009679 CHEBI:139335 biolink:ChemicalSubstance 6-chloro-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139335 chebi_ph7_3 CHEBI:139336 biolink:ChemicalSubstance 6,7-dichloro-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139336 chebi_ph7_3 CHEBI:139332 biolink:ChemicalSubstance 5-chloro-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139332 chebi_ph7_3 GO:0034624 biolink:BiologicalProcess obsolete DNA recombinase assembly involved in gene conversion at mating-type locus OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another. go-plus.json http://purl.obolibrary.org/obo/GO_0034624 GO:0010679 biolink:BiologicalProcess obsolete cinnamic acid biosynthetic process involved in salicylic acid metabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0010679 GO:0034625 biolink:BiologicalProcess fatty acid elongation, monounsaturated fatty acid Elongation of a fatty acid chain into which one C-C double bond has been introduced. go-plus.json http://purl.obolibrary.org/obo/GO_0034625 GO:0034626 biolink:BiologicalProcess fatty acid elongation, polyunsaturated fatty acid Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced. go-plus.json http://purl.obolibrary.org/obo/GO_0034626 GO:0010677 biolink:BiologicalProcess negative regulation of cellular carbohydrate metabolic process Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010677 GO:0034627 biolink:BiologicalProcess 'de novo' NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json de novo NAD biosynthetic process http://purl.obolibrary.org/obo/GO_0034627 GO:0010678 biolink:BiologicalProcess negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription. go-plus.json negative regulation of cellular carbohydrate metabolic process by transcriptional repression|negative regulation of cellular carbohydrate metabolic process by repression of transcription|negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent http://purl.obolibrary.org/obo/GO_0010678 GO:0034628 biolink:BiologicalProcess 'de novo' NAD biosynthetic process from aspartate The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json de novo NAD biosynthetic process from aspartate http://purl.obolibrary.org/obo/GO_0034628 GO:0034629 biolink:BiologicalProcess cellular protein-containing complex localization A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell. go-plus.json cellular protein complex localisation|cellular protein complex localization|establishment and maintenance of cellular protein complex localization http://purl.obolibrary.org/obo/GO_0034629 GO:0009690 biolink:BiologicalProcess cytokinin metabolic process The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators. go-plus.json cytokinin metabolism http://purl.obolibrary.org/obo/GO_0009690 goslim_chembl GO:0009691 biolink:BiologicalProcess cytokinin biosynthetic process The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators. go-plus.json cytokinin synthesis|cytokinin formation|cytokinin biosynthesis|cytokinin anabolism http://purl.obolibrary.org/obo/GO_0009691 GO:0009692 biolink:BiologicalProcess ethylene metabolic process The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. go-plus.json ethylene metabolism|ethene metabolic process|ethene metabolism http://purl.obolibrary.org/obo/GO_0009692 CHEBI:57297 biolink:ChemicalSubstance ent-kaur-16-en-19-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57297 chebi_ph7_3 GO:0010671 biolink:BiologicalProcess obsolete negative regulation of oxygen and reactive oxygen species metabolic process OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). go-plus.json negative regulation of oxygen and reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0010671 GO:0009682 biolink:BiologicalProcess induced systemic resistance A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0009682 GO:0009683 biolink:BiologicalProcess indoleacetic acid metabolic process The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants. go-plus.json IAA metabolic process|indoleacetic acid metabolism|indole acetic acid metabolic process|indole acetic acid metabolism http://purl.obolibrary.org/obo/GO_0009683 GO:0010672 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. go-plus.json regulation of meiosis by regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter, meiotic http://purl.obolibrary.org/obo/GO_0010672 CHEBI:57298 biolink:ChemicalSubstance ent-7alpha-hydroxykaur-16-en-19-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57298 chebi_ph7_3 GO:0009684 biolink:BiologicalProcess indoleacetic acid biosynthetic process The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants. go-plus.json indole-3-acetate biosynthesis|indole-3-acetate biosynthetic process|IAA biosynthetic process|indoleacetic acid biosynthesis|indoleacetic acid anabolism|indole-acetic acid biosynthesis|indoleacetic acid synthesis|indoleacetic acid formation|indole-acetic acid biosynthetic process|indole acetic acid biosynthetic process|indole acetic acid biosynthesis http://purl.obolibrary.org/obo/GO_0009684 CHEBI:140328 biolink:ChemicalSubstance alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140328 chebi_ph7_3 CHEBI:57295 biolink:ChemicalSubstance (-)-ephedrinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_57295 chebi_ph7_3 GO:0009685 biolink:BiologicalProcess gibberellin metabolic process The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators. go-plus.json gibberellin metabolism|gibberellic acid metabolism|gibberellic acid metabolic process http://purl.obolibrary.org/obo/GO_0009685 CHEBI:57296 biolink:ChemicalSubstance (-)-ureidoglycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_57296 chebi_ph7_3 CHEBI:140329 biolink:ChemicalSubstance 13-deoxycarminomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140329 chebi_ph7_3 GO:0010670 biolink:BiologicalProcess obsolete positive regulation of oxygen and reactive oxygen species metabolic process OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). go-plus.json positive regulation of oxygen and reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0010670 GO:0009686 biolink:BiologicalProcess gibberellin biosynthetic process The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators. MetaCyc:PWY-5036|MetaCyc:PWY-5035|MetaCyc:PWY-5052|MetaCyc:PWY-5070 go-plus.json gibberellic acid anabolism|gibberellic acid synthesis|gibberellic acid biosynthesis|gibberellic acid biosynthetic process|gibberellic acid formation|gibberellin biosynthesis http://purl.obolibrary.org/obo/GO_0009686 GO:0034620 biolink:BiologicalProcess cellular response to unfolded protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. go-plus.json heat shock protein activity http://purl.obolibrary.org/obo/GO_0034620 GO:0010675 biolink:BiologicalProcess regulation of cellular carbohydrate metabolic process Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010675 GO:0019009 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019009 CHEBI:140326 biolink:ChemicalSubstance tertiary carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140326 chebi_ph7_3 CHEBI:57293 biolink:ChemicalSubstance (+)-bornyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57293 chebi_ph7_3 GO:0009687 biolink:BiologicalProcess abscisic acid metabolic process The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. go-plus.json abscisic acid metabolism http://purl.obolibrary.org/obo/GO_0009687 CHEBI:140327 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140327 chebi_ph7_3 CHEBI:57294 biolink:ChemicalSubstance (+)-dihydrokaempferol 7-oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_57294 GO:0034621 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034621 GO:0010676 biolink:BiologicalProcess positive regulation of cellular carbohydrate metabolic process Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010676 GO:0009688 biolink:BiologicalProcess abscisic acid biosynthetic process The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. MetaCyc:PWY-695 go-plus.json abscisic acid biosynthesis|abscisic acid anabolism|abscisic acid synthesis|abscisic acid formation http://purl.obolibrary.org/obo/GO_0009688 GO:0010673 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. go-plus.json up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|activation of meiosis by positive regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, meiotic|positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0010673 GO:0034622 biolink:BiologicalProcess cellular protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell. go-plus.json cellular macromolecule complex assembly|cellular protein complex assembly http://purl.obolibrary.org/obo/GO_0034622 OBA:VT0015108 biolink:OntologyClass neurite morphology trait The morphology of a neuron projection. go-plus.json morphology of neuron projection http://purl.obolibrary.org/obo/OBA_VT0015108 CHEBI:140324 biolink:ChemicalSubstance primary carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140324 chebi_ph7_3 CHEBI:57291 biolink:ChemicalSubstance 3-oxopristanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57291 chebi_ph7_3 GO:0019007 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019007 GO:0019008 biolink:CellularComponent molybdopterin synthase complex A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits. go-plus.json molybdopterin converting factor complex http://purl.obolibrary.org/obo/GO_0019008 goslim_metagenomics GO:0009689 biolink:BiologicalProcess induction of phytoalexin biosynthetic process The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection. go-plus.json induction of phytoalexin anabolism|induction of phytoalexin synthesis|induction of phytoalexin formation|induction of phytoalexin biosynthesis http://purl.obolibrary.org/obo/GO_0009689 GO:0010674 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. go-plus.json up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, meiotic|activation of meiosis by negative regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0010674 CHEBI:140325 biolink:ChemicalSubstance secondary carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_140325 chebi_ph7_3 CHEBI:57292 biolink:ChemicalSubstance succinyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57292 chebi_ph7_3 GO:0034623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034623 GO:0019005 biolink:CellularComponent SCF ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). Wikipedia:SCF_complex go-plus.json CDL1 complex|Skp1/Cul1/F-box protein complex|cullin-RING ligase 1|SCF complex substrate recognition subunit|SCF complex|CRL1 complex|Cul1-RING ubiquitin ligase complex http://purl.obolibrary.org/obo/GO_0019005 GO:0019006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019006 GO:0019003 biolink:MolecularActivity GDP binding Binding to GDP, guanosine 5'-diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0019003 CHEBI:139346 biolink:ChemicalSubstance all-trans-4-hydroxyretinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_139346 chebi_ph7_3 GO:0019004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019004 CHEBI:139340 biolink:ChemicalSubstance 1,3-dihydroimidazole-2-thiones go-plus.json http://purl.obolibrary.org/obo/CHEBI_139340 chebi_ph7_3 GO:0019001 biolink:MolecularActivity guanyl nucleotide binding Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate. Reactome:R-HSA-156909 go-plus.json http://purl.obolibrary.org/obo/GO_0019001 GO:0019002 biolink:MolecularActivity GMP binding Binding to GMP, guanosine monophosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0019002 CHEBI:57299 biolink:ChemicalSubstance ATP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_57299 GO:0019000 biolink:MolecularActivity obsolete endonuclease G activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json endonuclease G activity http://purl.obolibrary.org/obo/GO_0019000 CHEBI:47804 biolink:ChemicalSubstance dibenzoazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47804 CHEBI:47805 biolink:ChemicalSubstance 25-hydroxy-24-oxocalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47805 chebi_ph7_3 CHEBI:47806 biolink:ChemicalSubstance oxocalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47806 CHEBI:23843 biolink:ChemicalSubstance disaccharide phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23843 CHEBI:23849 biolink:ChemicalSubstance diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23849 UBERON:0014283 biolink:AnatomicalEntity piriform cortex layer 3 Deepest of 3 cytoarchitecturally defined layers of the piriform cortex characterized by a moderately high density of pyramidal cells and large numbers of basal dendrites descending from pyramidal cells in layer 2. go-plus.json piriform cortex layer 3|layer 3 of piriform cortex|layer 3 of piriform cortex http://purl.obolibrary.org/obo/UBERON_0014283 CHEBI:23812 biolink:ChemicalSubstance dimethylmaleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23812 CHEBI:23818 biolink:ChemicalSubstance dimethylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23818 CHEBI:23816 biolink:ChemicalSubstance dimethylsilanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23816 chebi_ph7_3 CHEBI:23822 biolink:ChemicalSubstance dinitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23822 CHEBI:23825 biolink:ChemicalSubstance dibenzodioxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23825 CHEBI:23824 biolink:ChemicalSubstance diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23824 CHEBI:72800 biolink:ChemicalSubstance sphinga-4E,8E-dienine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72800 CHEBI:72801 biolink:ChemicalSubstance 5-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72801 CHEBI:72802 biolink:ChemicalSubstance 18-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72802 CHEBI:1449 biolink:ChemicalSubstance 3-amino-2-oxopropyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_1449 CHEBI:72804 biolink:ChemicalSubstance HOTrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72804 CHEBI:72805 biolink:ChemicalSubstance 2-alkyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72805 chebi_ph7_3 CHEBI:1447 biolink:ChemicalSubstance 3-acylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1447 CHEBI:72810 biolink:ChemicalSubstance 2'-deoxynebularine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72810 chebi_ph7_3 CHEBI:72812 biolink:ChemicalSubstance oxooctadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72812 CHEBI:72813 biolink:ChemicalSubstance exopolysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_72813 CHEBI:23809 biolink:ChemicalSubstance dimethylbenzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_23809 CHEBI:23806 biolink:ChemicalSubstance dimethylaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_23806 CHEBI:72823 biolink:ChemicalSubstance glycerophosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_72823 CHEBI:72824 biolink:ChemicalSubstance 1-(Z-alk-1-enyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72824 CHEBI:1427 biolink:ChemicalSubstance 3-(3-hydroxyphenyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1427 CHEBI:72826 biolink:ChemicalSubstance 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72826 chebi_ph7_3 CHEBI:72827 biolink:ChemicalSubstance 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72827 chebi_ph7_3 CHEBI:72828 biolink:ChemicalSubstance 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72828 chebi_ph7_3 CHEBI:72829 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72829 chebi_ph7_3 GO:0034594 biolink:MolecularActivity phosphatidylinositol trisphosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0034594 GO:0034595 biolink:MolecularActivity phosphatidylinositol phosphate 5-phosphatase activity Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate. go-plus.json phosphoinositide 5-phosphatase activity|polyphosphoinositol lipid 5-phosphatase activity http://purl.obolibrary.org/obo/GO_0034595 GO:0034596 biolink:MolecularActivity phosphatidylinositol phosphate 4-phosphatase activity Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate. Reactome:R-HSA-1676133|Reactome:R-HSA-8849969|Reactome:R-HSA-1675988|Reactome:R-HSA-1676124 go-plus.json inositol 4-phosphatase|phosphoinositide 4-phosphatase activity|PtdIns4P-phosphatase activity|PI(4)P-phosphatase activity|PI4P-phosphatase activity http://purl.obolibrary.org/obo/GO_0034596 GO:0034597 biolink:MolecularActivity phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. Reactome:R-HSA-6810410|MetaCyc:3.1.3.66-RXN|EC:3.1.3.66 go-plus.json phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity|inositol polyphosphate 4-phosphatase type II activity|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0034597 GO:0034598 biolink:MolecularActivity phosphothreonine lyase activity Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product. go-plus.json http://purl.obolibrary.org/obo/GO_0034598 GO:0034599 biolink:BiologicalProcess cellular response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json adaptive response to oxidative stress http://purl.obolibrary.org/obo/GO_0034599 GO:0034590 biolink:MolecularActivity L-hydroxyproline transmembrane transporter activity Enables the transfer of L-hydroxyproline from one side of a membrane to the other. Reactome:R-HSA-6784213 go-plus.json 4-hydroxyproline transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034590 GO:0034591 biolink:CellularComponent rhoptry lumen The volume enclosed by the rhoptry membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034591 GO:0034592 biolink:CellularComponent synaptic vesicle lumen The volume enclosed by the synaptic vesicle membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0034592 goslim_synapse GO:0034593 biolink:MolecularActivity phosphatidylinositol bisphosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate. go-plus.json triphosphoinositide phosphomonoesterase activity|phosphatidylinositol-bisphosphatase activity|diphosphoinositide phosphatase activity|triphosphoinositide phosphatase activity|phosphatidyl-inositol-bisphosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0034593 CHEBI:72830 biolink:ChemicalSubstance 2-hexadecanoyl-1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72830 chebi_ph7_3 CHEBI:72831 biolink:ChemicalSubstance 2-hexadecanoyl-1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72831 chebi_ph7_3 CHEBI:72832 biolink:ChemicalSubstance 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72832 chebi_ph7_3 CHEBI:72833 biolink:ChemicalSubstance 1-hexadecanoyl-sn--glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72833 chebi_ph7_3 CHEBI:72834 biolink:ChemicalSubstance 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72834 chebi_ph7_3 CHEBI:72835 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72835 chebi_ph7_3 CHEBI:72836 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72836 chebi_ph7_3 CHEBI:1438 biolink:ChemicalSubstance 3-(methylthio)propionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1438 CHEBI:72837 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72837 chebi_ph7_3 CHEBI:72838 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72838 chebi_ph7_3 CHEBI:72839 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72839 chebi_ph7_3 GO:0034583 biolink:MolecularActivity 21U-RNA binding Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. go-plus.json http://purl.obolibrary.org/obo/GO_0034583 GO:0034584 biolink:MolecularActivity piRNA binding Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. go-plus.json Piwi-associated RNA binding http://purl.obolibrary.org/obo/GO_0034584 GO:0034585 biolink:BiologicalProcess 21U-RNA metabolic process The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. go-plus.json 21U-RNA metabolism http://purl.obolibrary.org/obo/GO_0034585 GO:0034586 biolink:BiologicalProcess 21U-RNA catabolic process The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. go-plus.json 21U-RNA degradation|21U-RNA breakdown|21U-RNA catabolism http://purl.obolibrary.org/obo/GO_0034586 GO:0034587 biolink:BiologicalProcess piRNA metabolic process The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. go-plus.json piRNA metabolism|Piwi-associated RNA metabolic process http://purl.obolibrary.org/obo/GO_0034587 goslim_drosophila GO:0034588 biolink:BiologicalProcess piRNA catabolic process The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. go-plus.json piRNA degradation|piRNA breakdown|Piwi-associated RNA catabolic process|piRNA catabolism http://purl.obolibrary.org/obo/GO_0034588 GO:0034589 biolink:BiologicalProcess hydroxyproline transport The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-hydroxyproline transport|4-hydroxyproline transport http://purl.obolibrary.org/obo/GO_0034589 GO:0034580 biolink:MolecularActivity 4-methyloctanoyl-CoA dehydrogenase activity Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r0924|EC:1.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034580 GO:0034581 biolink:MolecularActivity 4-methyloct-2-enoyl-CoA hydratase activity Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA. UM-BBD_reactionID:r0925 go-plus.json http://purl.obolibrary.org/obo/GO_0034581 GO:0034582 biolink:MolecularActivity 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r0926 go-plus.json http://purl.obolibrary.org/obo/GO_0034582 CHEBI:47885 biolink:ChemicalSubstance dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_47885 NCBITaxon:321614 biolink:OrganismalEntity Parastagonospora nodorum SN15 go-plus.json Phaeosphaeria nodorum SN15 http://purl.obolibrary.org/obo/NCBITaxon_321614 CHEBI:47880 biolink:ChemicalSubstance steroid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_47880 CHEBI:47881 biolink:ChemicalSubstance 3-oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47881 CHEBI:47882 biolink:ChemicalSubstance cyclic polypyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_47882 CHEBI:33231 biolink:ChemicalSubstance antitubercular agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_33231 CHEBI:33232 biolink:ChemicalSubstance application go-plus.json http://purl.obolibrary.org/obo/CHEBI_33232 CHEBI:33233 biolink:ChemicalSubstance fundamental particle go-plus.json http://purl.obolibrary.org/obo/CHEBI_33233 CHEBI:33234 biolink:ChemicalSubstance vitamin E go-plus.json http://purl.obolibrary.org/obo/CHEBI_33234 CHEBI:33235 biolink:ChemicalSubstance tocotrienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33235 CHEBI:33237 biolink:ChemicalSubstance vitamin D4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_33237 chebi_ph7_3 CHEBI:33238 biolink:ChemicalSubstance monoatomic entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33238 CHEBI:47877 biolink:ChemicalSubstance hexose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47877 CHEBI:47878 biolink:ChemicalSubstance hexose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47878 CHEBI:47879 biolink:ChemicalSubstance 3-hydroxymethylcephalosporin go-plus.json http://purl.obolibrary.org/obo/CHEBI_47879 CHEBI:47870 biolink:ChemicalSubstance (methylthio)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47870 CHEBI:47871 biolink:ChemicalSubstance mercaptopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47871 CHEBI:33242 biolink:ChemicalSubstance inorganic hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_33242 CHEBI:33245 biolink:ChemicalSubstance organic fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_33245 CHEBI:33246 biolink:ChemicalSubstance inorganic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33246 CHEBI:33247 biolink:ChemicalSubstance organic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33247 CHEBI:33248 biolink:ChemicalSubstance hydrocarbyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33248 CHEBI:33249 biolink:ChemicalSubstance organyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_33249 UBERON:0004895 biolink:AnatomicalEntity alveolar smooth muscle Alveolar smooth muscle is a type of non-striated muscle, found within the walls of the alveolus go-plus.json http://purl.obolibrary.org/obo/UBERON_0004895 CHEBI:33240 biolink:ChemicalSubstance coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_33240 UBERON:0004893 biolink:AnatomicalEntity interalveolar septum A the thin septum that separates adjacent pulmonary alveoli, containing connective tissue constituents of the respiratory tissue and the capillary network of the blood supply of the lung. go-plus.json septum interalveolare|alveolar septum http://purl.obolibrary.org/obo/UBERON_0004893 UBERON:0004894 biolink:AnatomicalEntity alveolar wall A wall that contains the alveoli go-plus.json alveolus wall|pulmonary interalveolar septum|wall of pulmonary alveolus|pulmonary alveolar wall http://purl.obolibrary.org/obo/UBERON_0004894 CHEBI:33241 biolink:ChemicalSubstance oxoacid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_33241 CHEBI:23895 biolink:ChemicalSubstance ecdysteroid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_23895 CHEBI:23899 biolink:ChemicalSubstance icosanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23899 CHEBI:47867 biolink:ChemicalSubstance indicator go-plus.json http://purl.obolibrary.org/obo/CHEBI_47867 CHEBI:47868 biolink:ChemicalSubstance photosensitizing agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_47868 CHEBI:23897 biolink:ChemicalSubstance ecdysteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23897 UBERON:0004880 biolink:AnatomicalEntity chordamesoderm The central region of trunk mesoderm. This tissue forms the notochord go-plus.json presumptive notochord|chorda mesoderm|axial chorda mesoderm|dorsal mesoderm http://purl.obolibrary.org/obo/UBERON_0004880 CHEBI:1467 biolink:ChemicalSubstance (2S)-2-isopropyl-3-oxosuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1467 CHEBI:33216 biolink:ChemicalSubstance bisphenol A go-plus.json http://purl.obolibrary.org/obo/CHEBI_33216 chebi_ph7_3 CHEBI:47869 biolink:ChemicalSubstance thioglycolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_47869 UBERON:0004889 biolink:AnatomicalEntity lobar bronchus vasculature Vasculature that is composed of the tubule structures that carry blood or lymph in the lungs go-plus.json http://purl.obolibrary.org/obo/UBERON_0004889 UBERON:0004884 biolink:AnatomicalEntity lobar bronchus mesenchyme The mass of tissue composed of mesenchymal cells in the lobar bronchus.. go-plus.json mesenchyme of lobar bronchus http://purl.obolibrary.org/obo/UBERON_0004884 CHEBI:1461 biolink:ChemicalSubstance 3-butynoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1461 UBERON:0004883 biolink:AnatomicalEntity lung mesenchyme The mass of tissue made up of mesenchymal cells in the lung. go-plus.json pulmonary mesenchyme|lung-associated mesenchyme|mesenchyme of lung http://purl.obolibrary.org/obo/UBERON_0004883 UBERON:0004869 biolink:AnatomicalEntity parietal organ A part of the epithalamus present in some animal species. The eye may be photoreceptive and is usually associated with the pineal gland, regulating circadian rhythmicity and hormone production for thermoregulation. The parietal eye is a part of the epithalamus, which can be divided into two major parts; the epiphysis (the pineal organ, or pineal gland if mostly endocrine) and the parietal organ (often called the parietal eye, or third eye if it is photoreceptive). It arises as an anterior evagination of the pineal organ or as a separate outgrowth of the roof of the diencephalon. In some species, it protrudes through the skull.[4] The parietal eye uses a different biochemical method of detecting light than rod cells or cone cells in a normal vertebrate eye[WP]. go-plus.json third eye|parietal eye http://purl.obolibrary.org/obo/UBERON_0004869 CHEBI:47857 biolink:ChemicalSubstance ureas go-plus.json http://purl.obolibrary.org/obo/CHEBI_47857 CHEBI:33229 biolink:ChemicalSubstance vitamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_33229 CHEBI:33221 biolink:ChemicalSubstance corrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_33221 CHEBI:33224 biolink:ChemicalSubstance chromane go-plus.json http://purl.obolibrary.org/obo/CHEBI_33224 chebi_ph7_3 CHEBI:33227 biolink:ChemicalSubstance (E)-cinnamyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33227 chebi_ph7_3 CHEBI:47858 biolink:ChemicalSubstance 1-piperideine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47858 UBERON:0004875 biolink:AnatomicalEntity nephrogenic cord A portion of the urogenital ridge which is the source of much of the urinary system[WP]. go-plus.json chorda nephrogenica http://purl.obolibrary.org/obo/UBERON_0004875 UBERON:0004876 biolink:AnatomicalEntity urogenital fold One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]. go-plus.json urethral fold|urogenital ridge|urogenital fold http://purl.obolibrary.org/obo/UBERON_0004876 UBERON:0004873 biolink:AnatomicalEntity splanchnopleure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]. go-plus.json ventral splanchnic mesoderm http://purl.obolibrary.org/obo/UBERON_0004873 UBERON:0004874 biolink:AnatomicalEntity somatopleure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004874 UBERON:0004871 biolink:AnatomicalEntity somatic layer of lateral plate mesoderm Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]. go-plus.json outer layer of lateral plate mesoderm|somatic mesoderm|parietal mesoderm http://purl.obolibrary.org/obo/UBERON_0004871 CHEBI:1472 biolink:ChemicalSubstance 3-chloro-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1472 UBERON:0004872 biolink:AnatomicalEntity splanchnic layer of lateral plate mesoderm Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. go-plus.json inner layer of lateral plate mesoderm|visceral mesoderm|splanchnic mesoderm http://purl.obolibrary.org/obo/UBERON_0004872 CHEBI:23872 biolink:ChemicalSubstance dodecyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23872 chebi_ph7_3 CHEBI:47843 biolink:ChemicalSubstance dithiane go-plus.json http://purl.obolibrary.org/obo/CHEBI_47843 CHEBI:47844 biolink:ChemicalSubstance 1,2-dithiane go-plus.json http://purl.obolibrary.org/obo/CHEBI_47844 chebi_ph7_3 CHEBI:23875 biolink:ChemicalSubstance dolichol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23875 CHEBI:47830 biolink:ChemicalSubstance hydroxyarginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47830 CHEBI:47833 biolink:ChemicalSubstance methionine sulfoximine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47833 CHEBI:23888 biolink:ChemicalSubstance drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_23888 CHEBI:33203 biolink:ChemicalSubstance (Z)-24-ethylidenelophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_33203 chebi_ph7_3 CHEBI:47836 biolink:ChemicalSubstance oxo seco-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47836 CHEBI:47820 biolink:ChemicalSubstance (1S)-1-hydroxy-23-oxo-24,25,26,27-tetranorcalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47820 chebi_ph7_3 CHEBI:47821 biolink:ChemicalSubstance N(5)-[(E)-amino(hydroxyimino)methyl]-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47821 CHEBI:47822 biolink:ChemicalSubstance N(5)-[(Z)-amino(hydroxyimino)methyl]-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47822 CHEBI:47823 biolink:ChemicalSubstance N(omega)-hydroxyarginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47823 CHEBI:23853 biolink:ChemicalSubstance dithiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23853 CHEBI:23858 biolink:ChemicalSubstance behenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23858 chebi_ph7_3 CHEBI:47825 biolink:ChemicalSubstance N(5)-[(E)-amino(hydroxyimino)methyl]ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47825 CHEBI:47826 biolink:ChemicalSubstance N(5)-[amino(hydroxyimino)methyl]ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47826 CHEBI:47827 biolink:ChemicalSubstance N(5)-[(hydroxyamino)(imino)methyl]ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47827 CHEBI:47828 biolink:ChemicalSubstance calcitroic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47828 CHEBI:23866 biolink:ChemicalSubstance dodecanols go-plus.json http://purl.obolibrary.org/obo/CHEBI_23866 CHEBI:47811 biolink:ChemicalSubstance penamcarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47811 CHEBI:47812 biolink:ChemicalSubstance (1S)-1,25-dihydroxy-24-oxocalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47812 chebi_ph7_3 CHEBI:47813 biolink:ChemicalSubstance (1S)-1,23,25-trihydroxy-24-oxocalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47813 chebi_ph7_3 CHEBI:23869 biolink:ChemicalSubstance dodecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_23869 CHEBI:23867 biolink:ChemicalSubstance dodecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23867 CHEBI:47818 biolink:ChemicalSubstance (1S)-1,23-dihydroxy-24,25,26,27-tetranorcalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47818 chebi_ph7_3 CHEBI:47819 biolink:ChemicalSubstance N(5)-[amino(hydroxyimino)methyl]-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47819 NCBITaxon:1329911 biolink:OrganismalEntity Toxicofera go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1329911 UBERON:0004938 biolink:AnatomicalEntity submucosa of biliary tree A submucosa that is part of a biliary tree [Automatically generated definition]. go-plus.json biliary tree submucosa|biliary tract submucosa|submucosa of biliary tract http://purl.obolibrary.org/obo/UBERON_0004938 UBERON:0004939 biolink:AnatomicalEntity submucosa of common bile duct A submucosa that is part of a common bile duct [Automatically generated definition]. go-plus.json common bile ductal submucosa|ductus choledochus (biliaris) submucosa|common bile duct submucosa|submucosa of ductus choledochus (biliaris) http://purl.obolibrary.org/obo/UBERON_0004939 UBERON:0004936 biolink:AnatomicalEntity submucosa of pyloric antrum A submucosa that is part of a pyloric antrum [Automatically generated definition]. go-plus.json stomach pyloric antrum submucosa|antrum of stomach submucosa|submucosa of antrum of stomach|submucosa of stomach pyloric antrum|pyloric antrum submucosa http://purl.obolibrary.org/obo/UBERON_0004936 UBERON:0004937 biolink:AnatomicalEntity submucosa of pylorus A submucosa that is part of a pylorus [Automatically generated definition]. go-plus.json submucosa of stomach pyloric region|stomach pyloric region submucosa|pyloric part of stomach submucosa|pylorus submucosa|pyloric submucosa|submucosa of pyloric part of stomach http://purl.obolibrary.org/obo/UBERON_0004937 UBERON:0004934 biolink:AnatomicalEntity submucosa of body of stomach A submucosa that is part of a body of stomach [Automatically generated definition]. go-plus.json stomach body submucosa|submucosa of gastric body|gastric body submucosa|corpus gastricum (ventriculare) submucosa|submucosa of stomach body|submucosa of corpus gastricum (ventriculare)|body of stomach submucosa http://purl.obolibrary.org/obo/UBERON_0004934 GO:0010767 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010767 CHEBI:140432 biolink:ChemicalSubstance [(9Z)-hexadecenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140432 chebi_ph7_3 GO:0034734 biolink:CellularComponent transcription factor TFIIIC1 complex A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity. go-plus.json http://purl.obolibrary.org/obo/GO_0034734 GO:0010768 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010768 CHEBI:140433 biolink:ChemicalSubstance GDP-6-deoxy-alpha-D-altrose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140433 chebi_ph7_3 GO:0034735 biolink:CellularComponent transcription factor TFIIIC2 complex A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0034735 GO:0034736 biolink:MolecularActivity cholesterol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA. MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN|EC:2.3.1.26|RHEA:17729|KEGG_REACTION:R01461|Reactome:R-HSA-8876696 go-plus.json cholesterol ester synthetase activity|cholesterol acyltransferase activity|cholesteryl ester synthetase activity|ACAT activity|acyl coenzyme A-cholesterol-O-acyltransferase activity|acyl-CoA:cholesterol acyltransferase activity|acylcoenzyme A:cholesterol O-acyltransferase activity|acyl-CoA:cholesterol O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0034736 GO:0010765 biolink:BiologicalProcess positive regulation of sodium ion transport Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010765 GO:0010766 biolink:BiologicalProcess negative regulation of sodium ion transport Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010766 GO:0034737 biolink:MolecularActivity ergosterol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester. go-plus.json http://purl.obolibrary.org/obo/GO_0034737 GO:0034738 biolink:MolecularActivity lanosterol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester. go-plus.json http://purl.obolibrary.org/obo/GO_0034738 GO:0034739 biolink:MolecularActivity histone deacetylase activity (H4-K16 specific) Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein. go-plus.json http://purl.obolibrary.org/obo/GO_0034739 GO:0010769 biolink:BiologicalProcess regulation of cell morphogenesis involved in differentiation Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. go-plus.json http://purl.obolibrary.org/obo/GO_0010769 GO:0009780 biolink:BiologicalProcess photosynthetic NADP+ reduction An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions. go-plus.json http://purl.obolibrary.org/obo/GO_0009780 CHEBI:33198 biolink:ChemicalSubstance D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33198 GO:0009770 biolink:BiologicalProcess obsolete primary charge separation in photosystem I OBSOLETE. Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side. go-plus.json http://purl.obolibrary.org/obo/GO_0009770 GO:0009771 biolink:BiologicalProcess obsolete primary charge separation in photosystem II OBSOLETE. Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side. go-plus.json http://purl.obolibrary.org/obo/GO_0009771 GO:0010760 biolink:BiologicalProcess negative regulation of macrophage chemotaxis Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010760 CHEBI:33199 biolink:ChemicalSubstance propynoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33199 GO:0009772 biolink:BiologicalProcess photosynthetic electron transport in photosystem II A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I. go-plus.json http://purl.obolibrary.org/obo/GO_0009772 CHEBI:140439 biolink:ChemicalSubstance 3-geranyl-3-[(Z)-2-isocyanovinyl]-3H-indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_140439 chebi_ph7_3 GO:0009773 biolink:BiologicalProcess photosynthetic electron transport in photosystem I A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP. go-plus.json http://purl.obolibrary.org/obo/GO_0009773 GO:0010763 biolink:BiologicalProcess positive regulation of fibroblast migration Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. go-plus.json positive regulation of fibroblast cell migration http://purl.obolibrary.org/obo/GO_0010763 GO:0034730 biolink:CellularComponent SmD-containing SMN-Sm protein complex An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex. go-plus.json SMN-containing protein complex http://purl.obolibrary.org/obo/GO_0034730 GO:0009774 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009774 GO:0034731 biolink:CellularComponent Lsm-containing SMN-Sm protein complex An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA. go-plus.json SMN-containing protein complex http://purl.obolibrary.org/obo/GO_0034731 GO:0010764 biolink:BiologicalProcess negative regulation of fibroblast migration Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. go-plus.json negative regulation of fibroblast cell migration http://purl.obolibrary.org/obo/GO_0010764 GO:0009775 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009775 GO:0010761 biolink:BiologicalProcess fibroblast migration Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json fibroblast cell migration http://purl.obolibrary.org/obo/GO_0010761 GO:0009776 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009776 CHEBI:140434 biolink:ChemicalSubstance 3-[(Z)-2-isocyanovinyl]indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_140434 chebi_ph7_3 GO:0034732 biolink:CellularComponent transcription factor TFIIIB-alpha complex A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0034732 GO:0034733 biolink:CellularComponent transcription factor TFIIIB-beta complex A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters. go-plus.json http://purl.obolibrary.org/obo/GO_0034733 GO:0009777 biolink:BiologicalProcess photosynthetic phosphorylation Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation. go-plus.json photosynthetic ATP synthesis http://purl.obolibrary.org/obo/GO_0009777 GO:0010762 biolink:BiologicalProcess regulation of fibroblast migration Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. go-plus.json regulation of fibroblast cell migration http://purl.obolibrary.org/obo/GO_0010762 GO:0009778 biolink:BiologicalProcess cyclic photosynthetic phosphorylation A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I. go-plus.json http://purl.obolibrary.org/obo/GO_0009778 UBERON:0004943 biolink:AnatomicalEntity submucosa of urinary bladder The submucous layer of the wall of the urinary bladder. go-plus.json tela submucosa vesicae|bladder submucosa|tela submucosa vesicae urinariae|submucous layer of urinary bladder|submucosa of bladder|tela submucosa (vesica urinaria)|urinary bladder submucosa http://purl.obolibrary.org/obo/UBERON_0004943 CHEBI:33190 biolink:ChemicalSubstance 3-oxopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33190 chebi_ph7_3 GO:0009779 biolink:BiologicalProcess noncyclic photosynthetic phosphorylation A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II. go-plus.json http://purl.obolibrary.org/obo/GO_0009779 UBERON:0004941 biolink:AnatomicalEntity submucosa of right hepatic duct A submucosa that is part of a right hepatic duct [Automatically generated definition]. go-plus.json right hepatic duct submucosa|right hepatic ductal submucosa http://purl.obolibrary.org/obo/UBERON_0004941 OBO:GOCHE_26645 biolink:OntologyClass substance with semiochemical role go-plus.json http://purl.obolibrary.org/obo/GOCHE_26645 3_STAR UBERON:0004942 biolink:AnatomicalEntity submucosa of left hepatic duct A submucosa that is part of a left hepatic duct [Automatically generated definition]. go-plus.json left hepatic ductal submucosa|left hepatic duct submucosa http://purl.obolibrary.org/obo/UBERON_0004942 UBERON:0004940 biolink:AnatomicalEntity submucosa of common hepatic duct A submucosa that is part of a common hepatic duct [Automatically generated definition]. go-plus.json common hepatic ductal submucosa|hepatic duct submucosa|common hepatic duct submucosa|submucosa of hepatic duct http://purl.obolibrary.org/obo/UBERON_0004940 NCBITaxon:1329912 biolink:OrganismalEntity Episquamata go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1329912 CHEBI:33196 biolink:ChemicalSubstance (3R)-3-hydroxy-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33196 CHEBI:33197 biolink:ChemicalSubstance (R)-10-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33197 UBERON:0004929 biolink:AnatomicalEntity submucosa of ascending colon A submucosa that is part of an ascending colon [Automatically generated definition]. go-plus.json ascending colon submucosa http://purl.obolibrary.org/obo/UBERON_0004929 UBERON:0004927 biolink:AnatomicalEntity submucosa of cecum A submucosa that is part of a cecum [Automatically generated definition]. go-plus.json submucosa of intestinum crassum caecum|submucosa of caecum|cecum submucosa|intestinum crassum caecum submucosa|caecum submucosa http://purl.obolibrary.org/obo/UBERON_0004927 UBERON:0004926 biolink:AnatomicalEntity submucosa of cystic duct A submucosa that is part of a cystic duct [Automatically generated definition]. go-plus.json cystic ductal submucosa|cystic duct submucosa http://purl.obolibrary.org/obo/UBERON_0004926 UBERON:0004923 biolink:AnatomicalEntity organ component layer A part of a wall of an organ that forms a layer. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004923 UBERON:0004924 biolink:AnatomicalEntity submucosa of pharynx The tissue underlying the tunica mucosa of the pharynx. go-plus.json tela submucosa pharyngea|pharyngeal submucosa|submucous layer of pharynx|submucous coat of pharynx|pharyngobasilar fascia|pharynx submucosa|tela submucosa pharyngis http://purl.obolibrary.org/obo/UBERON_0004924 GO:0034723 biolink:BiologicalProcess DNA replication-dependent nucleosome organization The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation. go-plus.json DNA replication-dependent nucleosome organisation http://purl.obolibrary.org/obo/GO_0034723 GO:0010778 biolink:BiologicalProcess meiotic DNA repair synthesis involved in reciprocal meiotic recombination The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010778 GO:0034724 biolink:BiologicalProcess DNA replication-independent nucleosome organization The formation or destruction of chromatin structures, occurring outside the context of DNA replication. go-plus.json DNA replication-independent nucleosome organisation http://purl.obolibrary.org/obo/GO_0034724 GO:0010779 biolink:BiologicalProcess meiotic DNA repair synthesis involved in meiotic gene conversion The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. go-plus.json http://purl.obolibrary.org/obo/GO_0010779 PR:000008476 biolink:Protein orexin A protein that is a translation product of the human HCRT gene or a 1:1 ortholog thereof. go-plus.json hypocretin|PPORX|OX|PPOX|HCRT|Hcrt http://purl.obolibrary.org/obo/PR_000008476 GO:0010776 biolink:BiologicalProcess meiotic mismatch repair involved in meiotic gene conversion A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. go-plus.json http://purl.obolibrary.org/obo/GO_0010776 GO:0034725 biolink:BiologicalProcess DNA replication-dependent nucleosome disassembly The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0034725 GO:0034726 biolink:BiologicalProcess DNA replication-independent nucleosome disassembly The controlled breakdown of nucleosomes outside the context of DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0034726 GO:0010777 biolink:BiologicalProcess meiotic mismatch repair involved in reciprocal meiotic recombination A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010777 GO:0034727 biolink:BiologicalProcess piecemeal microautophagy of the nucleus Degradation of a cell nucleus by lysosomal microautophagy. go-plus.json PMN http://purl.obolibrary.org/obo/GO_0034727 GO:0034728 biolink:BiologicalProcess nucleosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. go-plus.json nucleosome organisation http://purl.obolibrary.org/obo/GO_0034728 GO:0034729 biolink:BiologicalProcess histone H3-K79 methylation The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone. go-plus.json histone H3 K79 methylation|histone H3K79me|histone lysine H3 K79 methylation http://purl.obolibrary.org/obo/GO_0034729 GO:0009790 biolink:BiologicalProcess embryo development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. Wikipedia:Embryogenesis go-plus.json embryogenesis and morphogenesis|embryonal development|embryogenesis http://purl.obolibrary.org/obo/GO_0009790 gocheck_do_not_manually_annotate|goslim_plant|goslim_generic|goslim_chembl GO:0009791 biolink:BiologicalProcess post-embryonic development The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. go-plus.json http://purl.obolibrary.org/obo/GO_0009791 goslim_plant GO:0009781 biolink:BiologicalProcess obsolete photosynthetic water oxidation OBSOLETE. Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle. go-plus.json photosynthetic water oxidation http://purl.obolibrary.org/obo/GO_0009781 GO:0010770 biolink:BiologicalProcess positive regulation of cell morphogenesis involved in differentiation Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. go-plus.json http://purl.obolibrary.org/obo/GO_0010770 GO:0009782 biolink:CellularComponent photosystem I antenna complex The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs). go-plus.json http://purl.obolibrary.org/obo/GO_0009782 GO:0010771 biolink:BiologicalProcess negative regulation of cell morphogenesis involved in differentiation Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. go-plus.json http://purl.obolibrary.org/obo/GO_0010771 GO:0009783 biolink:CellularComponent photosystem II antenna complex The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs). go-plus.json http://purl.obolibrary.org/obo/GO_0009783 GO:0009784 biolink:MolecularActivity transmembrane receptor histidine kinase activity Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0009784 GO:0019108 biolink:MolecularActivity aryl-aldehyde dehydrogenase (NAD) activity Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+. MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-RXN|RHEA:11804|UM-BBD_reactionID:r0394|EC:1.2.1.29 go-plus.json aryl-aldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019108 GO:0010774 biolink:BiologicalProcess meiotic strand invasion involved in reciprocal meiotic recombination The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010774 GO:0009785 biolink:BiologicalProcess blue light signaling pathway The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm. go-plus.json blue light signalling pathway http://purl.obolibrary.org/obo/GO_0009785 CHEBI:140426 biolink:ChemicalSubstance 2,4,6-trichlorophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140426 chebi_ph7_3 GO:0034720 biolink:BiologicalProcess histone H3-K4 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone. go-plus.json H3K4 demethylation (me1 me2 and me3) http://purl.obolibrary.org/obo/GO_0034720 GO:0010775 biolink:BiologicalProcess meiotic strand invasion involved in meiotic gene conversion The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. go-plus.json http://purl.obolibrary.org/obo/GO_0010775 GO:0009786 biolink:BiologicalProcess regulation of asymmetric cell division Any process that modulates the frequency, rate or extent of asymmetric cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0009786 GO:0019109 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019109 GO:0009787 biolink:BiologicalProcess regulation of abscisic acid-activated signaling pathway Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling. go-plus.json regulation of abscisic acid mediated signalling|regulation of abscisic acid mediated signaling pathway http://purl.obolibrary.org/obo/GO_0009787 GO:0034721 biolink:BiologicalProcess histone H3-K4 demethylation, trimethyl-H3-K4-specific The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone. go-plus.json H3K4 demethylation (me3)|histone H3-K4 tridemethylation http://purl.obolibrary.org/obo/GO_0034721 GO:0019106 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019106 GO:0010772 biolink:BiologicalProcess meiotic DNA recombinase assembly involved in reciprocal meiotic recombination The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010772 GO:0009788 biolink:BiologicalProcess negative regulation of abscisic acid-activated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling. go-plus.json negative regulation of abscisic acid mediated signaling pathway|down-regulation of abscisic acid mediated signaling|negative regulation of abscisic acid mediated signalling|downregulation of abscisic acid mediated signaling|down regulation of abscisic acid mediated signaling|inhibition of abscisic acid mediated signaling http://purl.obolibrary.org/obo/GO_0009788 GO:0034722 biolink:MolecularActivity gamma-glutamyl-peptidase activity Catalysis of the cleavage of a gamma-linked glutamate bond. RHEA:56784|EC:3.4.19.9|MetaCyc:3.4.19.9-RXN go-plus.json gamma-glutamyl hydrolase activity http://purl.obolibrary.org/obo/GO_0034722 GO:0019107 biolink:MolecularActivity myristoyltransferase activity Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule. Reactome:R-HSA-162914|Reactome:R-HSA-141367 go-plus.json http://purl.obolibrary.org/obo/GO_0019107 GO:0010773 biolink:BiologicalProcess meiotic DNA recombinase assembly involved in meiotic gene conversion The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. go-plus.json http://purl.obolibrary.org/obo/GO_0010773 GO:0019104 biolink:MolecularActivity DNA N-glycosylase activity Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. Reactome:R-HSA-110251|Reactome:R-HSA-9629483|Reactome:R-HSA-110248|Reactome:R-HSA-5649673|Reactome:R-HSA-9629497|Reactome:R-HSA-5649658|Reactome:R-HSA-9635996|Reactome:R-HSA-9636008|Reactome:R-HSA-9629470|Reactome:R-HSA-9629149|Reactome:R-HSA-110219|Reactome:R-HSA-110246|Reactome:R-HSA-110231|Reactome:R-HSA-9629499|Reactome:R-HSA-5220959|Reactome:R-HSA-9629492|Reactome:R-HSA-110234|Reactome:R-HSA-9629216|Reactome:R-HSA-5649664|Reactome:R-HSA-110218|Reactome:R-HSA-5221061|Reactome:R-HSA-5649681|Reactome:R-HSA-110250|Reactome:R-HSA-110232 go-plus.json DNA glycosylase activity|endonuclease VIII activity http://purl.obolibrary.org/obo/GO_0019104 GO:0009789 biolink:BiologicalProcess positive regulation of abscisic acid-activated signaling pathway Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling. go-plus.json positive regulation of abscisic acid mediated signaling pathway|positive regulation of abscisic acid mediated signalling|up regulation of abscisic acid mediated signaling|upregulation of abscisic acid mediated signaling|stimulation of abscisic acid mediated signaling|activation of abscisic acid mediated signaling|up-regulation of abscisic acid mediated signaling http://purl.obolibrary.org/obo/GO_0009789 UBERON:0004932 biolink:AnatomicalEntity submucosa of sigmoid colon A submucosa that is part of a sigmoid colon [Automatically generated definition]. go-plus.json sigmoid colon submucosa http://purl.obolibrary.org/obo/UBERON_0004932 GO:0019105 biolink:MolecularActivity N-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019105 GO:0019102 biolink:BiologicalProcess male somatic sex determination The determination of sex and sexual phenotypes in a male organism's soma. go-plus.json http://purl.obolibrary.org/obo/GO_0019102 UBERON:0004930 biolink:AnatomicalEntity submucosa of transverse colon A submucosa that is part of a transverse colon [Automatically generated definition]. go-plus.json transverse colon submucosa http://purl.obolibrary.org/obo/UBERON_0004930 UBERON:0004931 biolink:AnatomicalEntity submucosa of descending colon A submucosa that is part of a descending colon [Automatically generated definition]. go-plus.json descending colon submucosa http://purl.obolibrary.org/obo/UBERON_0004931 CHEBI:139446 biolink:ChemicalSubstance Man-1-6-Ins-1-P-Cer(d18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139446 GO:0019103 biolink:MolecularActivity pyrimidine nucleotide binding Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0019103 GO:0019100 biolink:BiologicalProcess male germ-line sex determination The determination of sex and sexual phenotype in a male organism's germ line. go-plus.json http://purl.obolibrary.org/obo/GO_0019100 GO:0019101 biolink:BiologicalProcess female somatic sex determination The determination of sex and sexual phenotypes in a female organism's soma. go-plus.json http://purl.obolibrary.org/obo/GO_0019101 NCBITaxon:237631 biolink:OrganismalEntity Ustilago maydis 521 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_237631 UBERON:0004916 biolink:AnatomicalEntity anal sphincter A sphincter muscle that is part of a anal region. go-plus.json sphincter analia|anal region sphincter http://purl.obolibrary.org/obo/UBERON_0004916 UBERON:0004917 biolink:AnatomicalEntity urethral sphincter A sphincter muscle surrounding the urethra. go-plus.json urethral sphincter muscle|sphincter muscle of urethra|sphincter of urethra|sphincter urethrae http://purl.obolibrary.org/obo/UBERON_0004917 UBERON:0004914 biolink:AnatomicalEntity duodenal papilla One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct. go-plus.json papilla duodenalis|papilla duodeni|papilla of duodenum http://purl.obolibrary.org/obo/UBERON_0004914 UBERON:0004915 biolink:AnatomicalEntity sphincter of hepatopancreatic ampulla muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]. go-plus.json musculus sphincter ampullae|hepatopancreatic ampullary sphincter|sphincter of ampulla of vater|Oddi's sphincter|sphincter of Oddi|musculus sphincter ampullae hepatopancreatica http://purl.obolibrary.org/obo/UBERON_0004915 UBERON:0004912 biolink:AnatomicalEntity biliary bud go-plus.json hepatic diverticulum http://purl.obolibrary.org/obo/UBERON_0004912 UBERON:0004913 biolink:AnatomicalEntity hepatopancreatic ampulla A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. go-plus.json ampulla of Vater|ampulla hepatopancreatica|papilla Vateri|Vater's ampulla|ampulla biliaropancreatica|biliaropancreatic ampulla|ampulla of bile duct|papilla duodeni major|ampulla Vaterii http://purl.obolibrary.org/obo/UBERON_0004913 GO:0010745 biolink:BiologicalProcess negative regulation of macrophage derived foam cell differentiation Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0010745 GO:0034712 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034712 GO:0034713 biolink:MolecularActivity type I transforming growth factor beta receptor binding Binding to a type I transforming growth factor beta receptor. go-plus.json baboon receptor ligand|transforming growth factor beta receptor type I binding|TGF-beta type I binding|babo binding|baboon binding|sax binding|saxophone binding|tkv ligand|thickveins ligand|transforming growth factor beta ligand binding to type I receptor|thickveins binding|type I TGF-beta binding|saxophone ligand|tkv binding|sax ligand|baboon ligand|babo ligand http://purl.obolibrary.org/obo/GO_0034713 GO:0010746 biolink:BiologicalProcess regulation of long-chain fatty acid import across plasma membrane Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json regulation of plasma membrane long-chain fatty acid transport http://purl.obolibrary.org/obo/GO_0010746 GO:0010743 biolink:BiologicalProcess regulation of macrophage derived foam cell differentiation Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0010743 GO:0034714 biolink:MolecularActivity type III transforming growth factor beta receptor binding Binding to a type III transforming growth factor beta receptor. go-plus.json TGF-beta type III binding|transforming growth factor beta receptor type III binding|transforming growth factor beta ligand binding to type III receptor|betaglycan binding|type IIII TGF-beta binding http://purl.obolibrary.org/obo/GO_0034714 GO:0034715 biolink:CellularComponent pICln-Sm protein complex A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG. go-plus.json 6S pICln complex http://purl.obolibrary.org/obo/GO_0034715 GO:0010744 biolink:BiologicalProcess positive regulation of macrophage derived foam cell differentiation Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0010744 GO:0010749 biolink:BiologicalProcess regulation of nitric oxide mediated signal transduction Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). go-plus.json regulation of nitric oxide-mediated signal transduction http://purl.obolibrary.org/obo/GO_0010749 GO:0034716 biolink:CellularComponent Gemin3-Gemin4-Gemin5 complex A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0034716 GO:0034717 biolink:CellularComponent Gemin6-Gemin7-unrip complex A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0034717 GO:0034718 biolink:CellularComponent SMN-Gemin2 complex A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034718 GO:0010747 biolink:BiologicalProcess positive regulation of long-chain fatty acid import across plasma membrane Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. go-plus.json positive regulation of plasma membrane long-chain fatty acid transport http://purl.obolibrary.org/obo/GO_0010747 GO:0034719 biolink:CellularComponent SMN-Sm protein complex A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm. go-plus.json SMN-containing protein complex http://purl.obolibrary.org/obo/GO_0034719 GO:0010748 biolink:BiologicalProcess negative regulation of long-chain fatty acid import across plasma membrane Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. go-plus.json negative regulation of plasma membrane long-chain fatty acid transport http://purl.obolibrary.org/obo/GO_0010748 CHEBI:139419 biolink:ChemicalSubstance beta-D-fructofuranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139419 GO:0009750 biolink:BiologicalProcess response to fructose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. go-plus.json response to fructose stimulus http://purl.obolibrary.org/obo/GO_0009750 GO:0009751 biolink:BiologicalProcess response to salicylic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus. go-plus.json response to salicylic acid stimulus|response to salicylate http://purl.obolibrary.org/obo/GO_0009751 GO:0009752 biolink:BiologicalProcess detection of salicylic acid stimulus The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of salicylic acid stimulus http://purl.obolibrary.org/obo/GO_0009752 GO:0010741 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010741 GO:0009753 biolink:BiologicalProcess response to jasmonic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus. go-plus.json response to jasmonic acid stimulus http://purl.obolibrary.org/obo/GO_0009753 GO:0010742 biolink:BiologicalProcess macrophage derived foam cell differentiation The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0010742 GO:0009754 biolink:BiologicalProcess detection of jasmonic acid stimulus The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule. go-plus.json perception of jasmonic acid stimulus http://purl.obolibrary.org/obo/GO_0009754 GO:0034710 biolink:MolecularActivity inhibin complex binding Binding to an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0034710 GO:0009755 biolink:BiologicalProcess hormone-mediated signaling pathway A series of molecular signals mediated by the detection of a hormone. go-plus.json hormone mediated signalling http://purl.obolibrary.org/obo/GO_0009755 GO:0034711 biolink:MolecularActivity inhibin binding Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers. go-plus.json inhibin monomer binding|inhibin beta-B binding|inhibin beta-A binding|inhibin alpha binding http://purl.obolibrary.org/obo/GO_0034711 GO:0010740 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010740 UBERON:0004921 biolink:AnatomicalEntity subdivision of digestive tract A proximal-distal subdivision of the digestive tract. go-plus.json alimentary system subdivision|subdivision of alimentary system|intestinal tract|segment of intestinal tract http://purl.obolibrary.org/obo/UBERON_0004921 GO:0009756 biolink:BiologicalProcess carbohydrate mediated signaling A series of molecular signals mediated by the detection of carbohydrate. go-plus.json carbohydrate mediated signalling http://purl.obolibrary.org/obo/GO_0009756 UBERON:0004922 biolink:AnatomicalEntity postnatal subventricular zone A mitotically active layer of cells surrounding the brain ventricles in the adult that consists of migrating neuroblasts, astrocytes and transitory amplifying progenitor cells[MP]. go-plus.json subventricular zone|SEZ|adult subventricular zone|postnatal subependymal zone|brain subventricular zone|subependymal plate|subventricular zone of brain|subependymal layer|postnatal subventricular zone|subependymal zone|SVZ|postnatal subependymal plate|postnatal subependymal layer http://purl.obolibrary.org/obo/UBERON_0004922 GO:0009757 biolink:BiologicalProcess hexose mediated signaling A series of molecular signals mediated by the detection of hexose. go-plus.json hexose mediated signalling http://purl.obolibrary.org/obo/GO_0009757 GO:0009758 biolink:BiologicalProcess carbohydrate utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism. go-plus.json sugar utilization http://purl.obolibrary.org/obo/GO_0009758 GO:0009759 biolink:BiologicalProcess indole glucosinolate biosynthetic process The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. go-plus.json indole glucosinolate anabolism|indole glucosinolate synthesis|indole glucosinolate formation|indole glucosinolate biosynthesis http://purl.obolibrary.org/obo/GO_0009759 CHEBI:139413 biolink:ChemicalSubstance 1-oleoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139413 CHEBI:33173 biolink:ChemicalSubstance benzimidazolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33173 UBERON:0004907 biolink:AnatomicalEntity lower digestive tract The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]. go-plus.json lower gastrointestinal tract|gut|lower GI tract http://purl.obolibrary.org/obo/UBERON_0004907 GO:0034709 biolink:CellularComponent methylosome A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains. go-plus.json 20S methyltransferase complex|20S methylosome http://purl.obolibrary.org/obo/GO_0034709 UBERON:0004908 biolink:AnatomicalEntity upper digestive tract The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum. go-plus.json upper GI tract|upper gastrointestinal tract http://purl.obolibrary.org/obo/UBERON_0004908 UBERON:0004905 biolink:AnatomicalEntity articulation Anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts. go-plus.json joint http://purl.obolibrary.org/obo/UBERON_0004905 UBERON:0004906 biolink:AnatomicalEntity ectodermal part of digestive tract A portion of the gut that is derived from ectoderm. go-plus.json gut ectoderm|ectodermal gut http://purl.obolibrary.org/obo/UBERON_0004906 UBERON:0004904 biolink:AnatomicalEntity neuron projection bundle connecting eye with brain A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila go-plus.json optic nerve (generic)|optic nerve http://purl.obolibrary.org/obo/UBERON_0004904 UBERON:0004901 biolink:AnatomicalEntity right lung lobar bronchus mesenchyme The right lung lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung lobar bronchus go-plus.json http://purl.obolibrary.org/obo/UBERON_0004901 UBERON:0004902 biolink:AnatomicalEntity urogenital sinus epithelium The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra go-plus.json epithelium of urogenital sinus|UGE http://purl.obolibrary.org/obo/UBERON_0004902 GO:0034701 biolink:MolecularActivity tripeptidase activity Catalysis of the hydrolysis of a tripeptide. EC:3.4.13.-|MetaCyc:3.4.11.4-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0034701 GO:0010756 biolink:BiologicalProcess positive regulation of plasminogen activation Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. go-plus.json http://purl.obolibrary.org/obo/GO_0010756 GO:0010757 biolink:BiologicalProcess negative regulation of plasminogen activation Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. go-plus.json inhibition of plasminogen activation http://purl.obolibrary.org/obo/GO_0010757 GO:0034702 biolink:CellularComponent ion channel complex A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0034702 GO:0034703 biolink:CellularComponent cation channel complex An ion channel complex through which cations pass. go-plus.json http://purl.obolibrary.org/obo/GO_0034703 GO:0010754 biolink:BiologicalProcess negative regulation of cGMP-mediated signaling Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. go-plus.json negative regulation of cGMP-mediated signalling http://purl.obolibrary.org/obo/GO_0010754 GO:0010755 biolink:BiologicalProcess regulation of plasminogen activation Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. go-plus.json http://purl.obolibrary.org/obo/GO_0010755 GO:0034704 biolink:CellularComponent calcium channel complex An ion channel complex through which calcium ions pass. go-plus.json http://purl.obolibrary.org/obo/GO_0034704 GO:0034705 biolink:CellularComponent potassium channel complex An ion channel complex through which potassium ions pass. go-plus.json http://purl.obolibrary.org/obo/GO_0034705 GO:0034706 biolink:CellularComponent sodium channel complex An ion channel complex through which sodium ions pass. go-plus.json http://purl.obolibrary.org/obo/GO_0034706 GO:0034707 biolink:CellularComponent chloride channel complex An ion channel complex through which chloride ions pass. go-plus.json http://purl.obolibrary.org/obo/GO_0034707 GO:0010758 biolink:BiologicalProcess regulation of macrophage chemotaxis Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010758 UBERON:0004909 biolink:AnatomicalEntity epithelium of gonad An epithelium surrounding a gonad. go-plus.json gonadal epithelium|gonadal sheath|gonad epithelium http://purl.obolibrary.org/obo/UBERON_0004909 GO:0034708 biolink:CellularComponent methyltransferase complex A protein complex that possesses methyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0034708 GO:0010759 biolink:BiologicalProcess positive regulation of macrophage chemotaxis Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010759 CHEBI:33187 biolink:ChemicalSubstance oxomalononitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_33187 chebi_ph7_3 OBO:GOCHE_26672 biolink:OntologyClass substance with siderophore role go-plus.json http://purl.obolibrary.org/obo/GOCHE_26672 3_STAR GO:0009760 biolink:BiologicalProcess C4 photosynthesis The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch. Wikipedia:C4_carbon_fixation go-plus.json http://purl.obolibrary.org/obo/GO_0009760 CHEBI:33189 biolink:ChemicalSubstance hydrazonomalononitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_33189 chebi_ph7_3 GO:0009761 biolink:BiologicalProcess CAM photosynthesis The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis. Wikipedia:Crassulacean_acid_metabolism go-plus.json http://purl.obolibrary.org/obo/GO_0009761 GO:0009762 biolink:BiologicalProcess NADP-malic enzyme C4 photosynthesis The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme. MetaCyc:PWY-241 go-plus.json http://purl.obolibrary.org/obo/GO_0009762 CHEBI:140403 biolink:ChemicalSubstance N-acyl-1-[(1Z)-alkenyl]-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140403 chebi_ph7_3 GO:0010752 biolink:BiologicalProcess regulation of cGMP-mediated signaling Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. go-plus.json regulation of cGMP-mediated signalling http://purl.obolibrary.org/obo/GO_0010752 GO:0009763 biolink:BiologicalProcess NAD-malic enzyme C4 photosynthesis The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0009763 GO:0010753 biolink:BiologicalProcess positive regulation of cGMP-mediated signaling Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. go-plus.json positive regulation of cGMP-mediated signalling http://purl.obolibrary.org/obo/GO_0010753 GO:0009764 biolink:BiologicalProcess PEP carboxykinase C4 photosynthesis The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK). go-plus.json http://purl.obolibrary.org/obo/GO_0009764 GO:0009765 biolink:BiologicalProcess photosynthesis, light harvesting Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers. go-plus.json energy dissipation http://purl.obolibrary.org/obo/GO_0009765 GO:0010750 biolink:BiologicalProcess positive regulation of nitric oxide mediated signal transduction Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). go-plus.json positive regulation of nitric oxide-mediated signal transduction http://purl.obolibrary.org/obo/GO_0010750 GO:0010751 biolink:BiologicalProcess negative regulation of nitric oxide mediated signal transduction Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). go-plus.json negative regulation of nitric oxide-mediated signal transduction http://purl.obolibrary.org/obo/GO_0010751 GO:0034700 biolink:MolecularActivity allulose 6-phosphate 3-epimerase activity Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate. RHEA:28426|MetaCyc:RXN0-304 go-plus.json http://purl.obolibrary.org/obo/GO_0034700 GO:0009766 biolink:BiologicalProcess obsolete primary charge separation OBSOLETE. In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0009766 GO:0009767 biolink:BiologicalProcess photosynthetic electron transport chain A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient. go-plus.json photosynthetic electron transport in plastoquinone|photosynthetic electron transport in cytochrome b6/f|electron carrier, chlorophyll electron transport system|photosynthetic electron transport in plastocyanin http://purl.obolibrary.org/obo/GO_0009767 UBERON:0004910 biolink:AnatomicalEntity epithelium of male gonad An epithelium surrounding a testis. go-plus.json testis sheath|testis epithelium http://purl.obolibrary.org/obo/UBERON_0004910 UBERON:0004911 biolink:AnatomicalEntity epithelium of female gonad An epithelium surrounding an ovary. go-plus.json ovarian sheath|ovarian epithelium|ovary epithelium http://purl.obolibrary.org/obo/UBERON_0004911 GO:0009768 biolink:BiologicalProcess photosynthesis, light harvesting in photosystem I After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center. go-plus.json http://purl.obolibrary.org/obo/GO_0009768 GO:0009769 biolink:BiologicalProcess photosynthesis, light harvesting in photosystem II After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center. go-plus.json http://purl.obolibrary.org/obo/GO_0009769 CHEBI:33184 biolink:ChemicalSubstance long-chain fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_33184 CHEBI:33186 biolink:ChemicalSubstance malononitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_33186 chebi_ph7_3 GO:0010729 biolink:BiologicalProcess positive regulation of hydrogen peroxide biosynthetic process Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. go-plus.json positive regulation of hydrogen peroxide biosynthesis http://purl.obolibrary.org/obo/GO_0010729 NCBITaxon:1329950 biolink:OrganismalEntity Unidentata go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1329950 GO:0044104 biolink:MolecularActivity 2,5-dioxovalerate dehydrogenase (NAD+) activity Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+. go-plus.json 2,5-dioxopentanoate dehydrogenase (NAD+) activity|2,5-dioxopentanoate:NAD+ 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0044104 GO:0010723 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to iron Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010723 GO:0010724 biolink:BiologicalProcess regulation of definitive erythrocyte differentiation Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis. go-plus.json regulation of definitive erythropoiesis|regulation of definitive RBC differentiation|regulation of definitive red blood cell differentiation http://purl.obolibrary.org/obo/GO_0010724 GO:0044105 biolink:MolecularActivity L-xylulose reductase (NAD+) activity Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+. go-plus.json http://purl.obolibrary.org/obo/GO_0044105 GO:0044102 biolink:MolecularActivity purine deoxyribosyltransferase activity Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor. go-plus.json purine 2'-deoxyribosyltransferase activity|PTD http://purl.obolibrary.org/obo/GO_0044102 GO:0010721 biolink:BiologicalProcess negative regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010721 GO:0010722 biolink:BiologicalProcess regulation of ferrochelatase activity Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+. go-plus.json http://purl.obolibrary.org/obo/GO_0010722 GO:0044103 biolink:MolecularActivity L-arabinose 1-dehydrogenase (NADP+) activity Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+. EC:1.1.1.376 go-plus.json http://purl.obolibrary.org/obo/GO_0044103 GO:0044100 biolink:CellularComponent sporoplasm The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms. go-plus.json http://purl.obolibrary.org/obo/GO_0044100 GO:0010727 biolink:BiologicalProcess negative regulation of hydrogen peroxide metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. go-plus.json negative regulation of hydrogen peroxide metabolism http://purl.obolibrary.org/obo/GO_0010727 GO:0010728 biolink:BiologicalProcess regulation of hydrogen peroxide biosynthetic process Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. go-plus.json regulation of hydrogen peroxide biosynthesis http://purl.obolibrary.org/obo/GO_0010728 GO:0044101 biolink:MolecularActivity (R)-citramalyl-CoA lyase activity Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA. EC:4.1.3.46|MetaCyc:RXN-8967 go-plus.json R-citramalyl-CoA lyase activity|Ccl http://purl.obolibrary.org/obo/GO_0044101 GO:0010725 biolink:BiologicalProcess regulation of primitive erythrocyte differentiation Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis. go-plus.json regulation of primitive erythropoeisis|regulation of primitive RBC differentiation|regulation of primitive red blood cell differentiation http://purl.obolibrary.org/obo/GO_0010725 GO:0010726 biolink:BiologicalProcess positive regulation of hydrogen peroxide metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. go-plus.json positive regulation of hydrogen peroxide metabolism http://purl.obolibrary.org/obo/GO_0010726 UBERON:0004980 biolink:AnatomicalEntity mucosa of ureter A mucosa that is part of a ureter [Automatically generated definition]. go-plus.json tunica mucosa (ureter)|ureter mucosa of organ|ureteral mucosa|mucosal layer of ureter|tunica mucosa ureteris|ureter mucous membrane|ureter organ mucosa|organ mucosa of ureter|ureteric mucosa|ureter mucosa|mucosa of organ of ureter|mucous membrane of ureter http://purl.obolibrary.org/obo/UBERON_0004980 GO:0009730 biolink:BiologicalProcess detection of carbohydrate stimulus The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of carbohydrate stimulus http://purl.obolibrary.org/obo/GO_0009730 GO:0044108 biolink:BiologicalProcess cellular alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, carried out at the level of an individual cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044108 GO:0010720 biolink:BiologicalProcess positive regulation of cell development Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010720 GO:0044109 biolink:BiologicalProcess cellular alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044109 GO:0009731 biolink:BiologicalProcess detection of sucrose stimulus The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of sucrose stimulus http://purl.obolibrary.org/obo/GO_0009731 GO:0044106 biolink:BiologicalProcess cellular amine metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. go-plus.json http://purl.obolibrary.org/obo/GO_0044106 GO:0009732 biolink:BiologicalProcess detection of hexose stimulus The series of events in which a stimulus from a hexose is received and converted into a molecular signal. go-plus.json perception of hexose stimulus http://purl.obolibrary.org/obo/GO_0009732 GO:0044107 biolink:BiologicalProcess cellular alcohol metabolic process The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044107 GO:0009733 biolink:BiologicalProcess response to auxin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus. go-plus.json response to auxin stimulus http://purl.obolibrary.org/obo/GO_0009733 GO:0009734 biolink:BiologicalProcess auxin-activated signaling pathway A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription. go-plus.json auxin-regulated transcription|auxin mediated signalling|auxin signal transduction|auxin signaling|auxin mediated signaling pathway http://purl.obolibrary.org/obo/GO_0009734 GO:0009735 biolink:BiologicalProcess response to cytokinin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus. go-plus.json response to cytokinin stimulus http://purl.obolibrary.org/obo/GO_0009735 UBERON:0004988 biolink:AnatomicalEntity mucosa of cystic duct A mucosa that is part of a cystic duct [Automatically generated definition]. go-plus.json mucosa of organ of cystic duct|cystic duct organ mucosa|organ mucosa of cystic duct|cystic duct mucosa of organ|cystic duct mucous membrane|cystic duct mucosa|mucous membrane of cystic duct|cystic ductal mucosa http://purl.obolibrary.org/obo/UBERON_0004988 UBERON:0004985 biolink:AnatomicalEntity mucosa of ejaculatory duct A mucosa that is part of a ejaculatory duct [Automatically generated definition]. go-plus.json ejaculatory duct mucosa of organ|ejaculatory duct mucous membrane|ejaculatory ductal mucosa|organ mucosa of ejaculatory duct|ejaculatory duct organ mucosa|mucosa of organ of ejaculatory duct|mucous membrane of ejaculatory duct|ejaculatory duct mucosa http://purl.obolibrary.org/obo/UBERON_0004985 GO:0009736 biolink:BiologicalProcess cytokinin-activated signaling pathway A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json cytokinin mediated signalling|cytokinin mediated signaling pathway|cytokinin signaling http://purl.obolibrary.org/obo/GO_0009736 UBERON:0004986 biolink:AnatomicalEntity mucosa of deferent duct A mucosa that is part of a vas deferens [Automatically generated definition]. go-plus.json vas deferen mucous membrane|sperm duct mucosa|tunica mucosa (ductus deferens)|vas deferens organ mucosa|sperm duct mucous membrane|vas deferen mucosa|mucosa of organ of vas deferens|mucous membrane of deferent duct|ductus deferens mucosa of organ|organ mucosa of ductus deferens|mucosa of vas deferens|mucosa of organ of deferent duct|mucous membrane of vas deferens|ductus deferens organ mucosa|organ mucosa of sperm duct|deferent duct mucosa|mucous membrane of vas deferen|ductus deferens mucous membrane|mucosa of vas deferen|vas deferens mucosa of organ|mucosa of organ of vas deferen|sperm duct organ mucosa|vas deferens mucosa|vas deferens mucous membrane|organ mucosa of deferent duct|deferent duct mucosa of organ|mucosa of organ of sperm duct|vas deferen organ mucosa|mucous membrane of ductus deferens|deferent ductal mucosa|mucosa of ductus deferens|tunica mucosa ductus deferentis|mucosa of sperm duct|ductus deferens mucosa|organ mucosa of vas deferens|deferent duct mucous membrane|organ mucosa of vas deferen|mucosa of organ of ductus deferens|mucous membrane of sperm duct|vas deferen mucosa of organ|deferent duct organ mucosa|sperm duct mucosa of organ http://purl.obolibrary.org/obo/UBERON_0004986 GO:0009737 biolink:BiologicalProcess response to abscisic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. go-plus.json response to abscisic acid stimulus http://purl.obolibrary.org/obo/GO_0009737 UBERON:0004983 biolink:AnatomicalEntity mucosa of vagina A mucosa that is part of a vagina [Automatically generated definition]. go-plus.json vagina mucosa|vagina mucous membrane|organ mucosa of vagina|vaginal mucosa|vagina organ mucosa|mucosa of organ of vagina|tunica mucosa vaginae|mucous membrane of vagina|vagina mucosa of organ http://purl.obolibrary.org/obo/UBERON_0004983 GO:0009738 biolink:BiologicalProcess abscisic acid-activated signaling pathway A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription. go-plus.json abscisic acid mediated signalling|abscisic acid-mediated signaling pathway|abscisic acid signal transduction|ABA signal transduction|ABA signaling http://purl.obolibrary.org/obo/GO_0009738 UBERON:0004984 biolink:AnatomicalEntity mucosa of seminal vesicle A mucosa that is part of a seminal vesicle [Automatically generated definition]. go-plus.json organ mucosa of seminal gland|seminal gland mucosa of organ|seminal vesicle mucous membrane|seminal vesicle mucosa|seminal gland mucous membrane|mucous membrane of seminal vesicle|seminal gland organ mucosa|mucosa of organ of seminal vesicle|mucous membrane of seminal gland|tunica mucosa glandulae vesiculosae|mucosa of seminal gland|seminal vesicle organ mucosa|mucosa of organ of seminal gland|seminal vesicle mucosa of organ|organ mucosa of seminal vesicle|seminal gland mucosa http://purl.obolibrary.org/obo/UBERON_0004984 GO:0009739 biolink:BiologicalProcess response to gibberellin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus. go-plus.json response to gibberellin stimulus|response to gibberellic acid stimulus http://purl.obolibrary.org/obo/GO_0009739 CHEBI:47795 biolink:ChemicalSubstance (R)-dihydrocamalexic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47795 CHEBI:47796 biolink:ChemicalSubstance (S)-dihydrocamalexic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47796 CHEBI:47798 biolink:ChemicalSubstance xi-progoitrin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_47798 chebi_ph7_3 CHEBI:47799 biolink:ChemicalSubstance calcitetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47799 chebi_ph7_3 NCBITaxon:1329961 biolink:OrganismalEntity Bifurcata go-plus.json split-tongued squamates http://purl.obolibrary.org/obo/NCBITaxon_1329961 GO:0044115 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044115 GO:0010734 biolink:BiologicalProcess negative regulation of protein glutathionylation Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. go-plus.json negative regulation of protein amino acid glutathionylation http://purl.obolibrary.org/obo/GO_0010734 GO:0010735 biolink:BiologicalProcess positive regulation of transcription via serum response element binding Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum. go-plus.json http://purl.obolibrary.org/obo/GO_0010735 GO:0044116 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044116 GO:0010732 biolink:BiologicalProcess regulation of protein glutathionylation Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. go-plus.json regulation of protein amino acid glutathionylation http://purl.obolibrary.org/obo/GO_0010732 GO:0044113 biolink:BiologicalProcess obsolete development in other organism involved in symbiotic interaction OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism. go-plus.json development in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0044113 GO:0044114 biolink:BiologicalProcess development of symbiont in host The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json development of symbiont in host intercellular space|development of symbiont in host vascular tissue http://purl.obolibrary.org/obo/GO_0044114 GO:0010733 biolink:BiologicalProcess positive regulation of protein glutathionylation Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. go-plus.json positive regulation of protein amino acid glutathionylation http://purl.obolibrary.org/obo/GO_0010733 CHEBI:47790 biolink:ChemicalSubstance furofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_47790 GO:0010738 biolink:BiologicalProcess regulation of protein kinase A signaling Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. go-plus.json regulation of PKA signaling cascade|regulation of protein kinase A signalling cascade|regulation of protein kinase A signaling cascade http://purl.obolibrary.org/obo/GO_0010738 CHEBI:47791 biolink:ChemicalSubstance phenylacetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_47791 chebi_ph7_3 GO:0044111 biolink:BiologicalProcess formation of structure involved in a symbiotic process The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. go-plus.json development on or near surface of other organism involved in symbiotic interaction|development of symbiont during interaction with host|development of symbiont involved in interaction with host|development during symbiotic interaction|development involved in symbiotic interaction|development on or near surface of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0044111 GO:0044112 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044112 GO:0010739 biolink:BiologicalProcess positive regulation of protein kinase A signaling Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. go-plus.json positive regulation of PKA signaling cascade|positive regulation of protein kinase A signaling cascade|positive regulation of protein kinase A signalling cascade http://purl.obolibrary.org/obo/GO_0010739 GO:0010736 biolink:MolecularActivity serum response element binding Binding to a serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum. go-plus.json http://purl.obolibrary.org/obo/GO_0010736 CHEBI:47793 biolink:ChemicalSubstance (E)-phenylacetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_47793 chebi_ph7_3 GO:0010737 biolink:BiologicalProcess protein kinase A signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. go-plus.json protein kinase A signaling cascade|PKA signaling cascade|protein kinase A signal transduction|protein kinase A signalling cascade http://purl.obolibrary.org/obo/GO_0010737 GO:0044110 biolink:BiologicalProcess obsolete growth involved in symbiotic interaction OBSOLETE. The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction. go-plus.json growth on or near surface of other organism involved in symbiotic interaction|growth on or near surface of other organism during symbiotic interaction|growth during symbiotic interaction http://purl.obolibrary.org/obo/GO_0044110 CHEBI:47794 biolink:ChemicalSubstance dihydrocamalexic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47794 GO:0009740 biolink:BiologicalProcess gibberellic acid mediated signaling pathway A series of molecular signals mediated by the detection of gibberellic acid. go-plus.json gibberellic acid signaling|GA-signaling|gibberellic acid mediated signalling http://purl.obolibrary.org/obo/GO_0009740 GO:0010730 biolink:BiologicalProcess negative regulation of hydrogen peroxide biosynthetic process Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. go-plus.json negative regulation of hydrogen peroxide biosynthesis http://purl.obolibrary.org/obo/GO_0010730 GO:0009741 biolink:BiologicalProcess response to brassinosteroid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus. go-plus.json response to brassinosteroid stimulus http://purl.obolibrary.org/obo/GO_0009741 GO:0044119 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044119 GO:0010731 biolink:BiologicalProcess protein glutathionylation The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. go-plus.json protein amino acid glutathionylation http://purl.obolibrary.org/obo/GO_0010731 GO:0009742 biolink:BiologicalProcess brassinosteroid mediated signaling pathway A series of molecular signals mediated by the detection of brassinosteroid. go-plus.json brassinosteroid mediated signalling http://purl.obolibrary.org/obo/GO_0009742 GO:0044117 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044117 GO:0009743 biolink:BiologicalProcess response to carbohydrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. go-plus.json response to carbohydrate stimulus http://purl.obolibrary.org/obo/GO_0009743 GO:0009744 biolink:BiologicalProcess response to sucrose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus. go-plus.json response to sucrose stimulus http://purl.obolibrary.org/obo/GO_0009744 GO:0044118 biolink:BiologicalProcess obsolete development of symbiont in host cell OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044118 GO:0009745 biolink:BiologicalProcess sucrose mediated signaling A series of molecular signals mediated by the detection of sucrose. go-plus.json sucrose mediated signalling http://purl.obolibrary.org/obo/GO_0009745 GO:0009746 biolink:BiologicalProcess response to hexose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. go-plus.json response to hexose stimulus http://purl.obolibrary.org/obo/GO_0009746 CHEBI:139400 biolink:ChemicalSubstance N-acyllysophosphatidyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139400 CHEBI:139401 biolink:ChemicalSubstance N-hexadecanoyl-1-[(1Z)-octadecenoyl]-2-oleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139401 GO:0009747 biolink:BiologicalProcess hexokinase-dependent signaling A series of molecular signals mediated by hexose and dependent on the detection of hexokinase. go-plus.json hexokinase-dependent signalling http://purl.obolibrary.org/obo/GO_0009747 GO:0009748 biolink:BiologicalProcess hexokinase-independent signaling A series of molecular signals mediated by hexose and independent of hexokinase. go-plus.json hexokinase-independent signalling http://purl.obolibrary.org/obo/GO_0009748 GO:0009749 biolink:BiologicalProcess response to glucose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. go-plus.json response to glucose stimulus http://purl.obolibrary.org/obo/GO_0009749 CHEBI:33163 biolink:ChemicalSubstance dec-9-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33163 chebi_ph7_3 GO:0010709 biolink:BiologicalProcess heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences. go-plus.json http://purl.obolibrary.org/obo/GO_0010709 CHEBI:47784 biolink:ChemicalSubstance nucleotide conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_47784 GO:0010707 biolink:BiologicalProcess globoside biosynthetic process via lactosylceramide The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. go-plus.json globoside biosynthesis via lactosylceramide biosynthesis|biosynthesis of lactosylceramide precursor to globoside|lactosylceramide biosynthesis leading to globoside|lactosylceramide biosynthetic process leading to globoside http://purl.obolibrary.org/obo/GO_0010707 CHEBI:47786 biolink:ChemicalSubstance 16-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47786 chebi_ph7_3 GO:0010708 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010708 CHEBI:47787 biolink:ChemicalSubstance 11-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47787 chebi_ph7_3 CHEBI:47788 biolink:ChemicalSubstance 3-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47788 chebi_ph7_3 CHEBI:47789 biolink:ChemicalSubstance 7-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47789 chebi_ph7_3 GO:0010701 biolink:BiologicalProcess positive regulation of norepinephrine secretion Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. go-plus.json http://purl.obolibrary.org/obo/GO_0010701 GO:0044126 biolink:BiologicalProcess obsolete regulation of growth of symbiont in host OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044126 GO:0044127 biolink:BiologicalProcess regulation of development of symbiont in host Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044127 GO:0010702 biolink:BiologicalProcess obsolete regulation of histolysis OBSOLETE. Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0010702 GO:0044124 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044124 GO:0044125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044125 GO:0010700 biolink:BiologicalProcess negative regulation of norepinephrine secretion Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. go-plus.json http://purl.obolibrary.org/obo/GO_0010700 GO:0010705 biolink:BiologicalProcess meiotic DNA double-strand break processing involved in reciprocal meiotic recombination The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010705 GO:0044122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044122 GO:0044123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044123 GO:0010706 biolink:BiologicalProcess ganglioside biosynthetic process via lactosylceramide The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. go-plus.json biosynthesis of lactosylceramide precursor to ganglioside|ganglioside biosynthesis via lactosylceramide biosynthesis|lactosylceramide biosynthetic process leading to ganglioside|lactosylceramide biosynthesis leading to ganglioside http://purl.obolibrary.org/obo/GO_0010706 CHEBI:47781 biolink:ChemicalSubstance desipramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_47781 GO:0044120 biolink:BiologicalProcess obsolete development of symbiont in host vacuole OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring in a host vacuole. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json development of symbiont in host organelle http://purl.obolibrary.org/obo/GO_0044120 GO:0010703 biolink:BiologicalProcess obsolete negative regulation of histolysis OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death. go-plus.json inhibition of histolysis|down-regulation of histolysis|downregulation of histolysis|down regulation of histolysis http://purl.obolibrary.org/obo/GO_0010703 GO:0044121 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044121 GO:0010704 biolink:BiologicalProcess meiotic DNA double-strand break processing involved in meiotic gene conversion The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another. go-plus.json http://purl.obolibrary.org/obo/GO_0010704 CHEBI:47783 biolink:ChemicalSubstance cyclopentafuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_47783 GO:0009710 biolink:BiologicalProcess tropane alkaloid biosynthetic process The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system. go-plus.json tropane alkaloid anabolism|tropane alkaloid synthesis|tropane alkaloid formation|tropane alkaloid biosynthesis http://purl.obolibrary.org/obo/GO_0009710 GO:0044128 biolink:BiologicalProcess obsolete positive regulation of growth of symbiont in host OBSOLETE. Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044128 GO:0009711 biolink:BiologicalProcess purine alkaloid biosynthetic process The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure. go-plus.json purine alkaloid formation|purine alkaloid anabolism|purine alkaloid synthesis|purine alkaloid biosynthesis http://purl.obolibrary.org/obo/GO_0009711 GO:0044129 biolink:BiologicalProcess positive regulation of development of symbiont in host Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044129 GO:0009712 biolink:BiologicalProcess catechol-containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. go-plus.json catechol metabolism|catechol metabolic process http://purl.obolibrary.org/obo/GO_0009712 GO:0009713 biolink:BiologicalProcess catechol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. go-plus.json catechol formation|catechol biosynthesis|catechol biosynthetic process|catechol anabolism|catechol synthesis http://purl.obolibrary.org/obo/GO_0009713 GO:0009714 biolink:BiologicalProcess chalcone metabolic process The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives. go-plus.json chalcone metabolism http://purl.obolibrary.org/obo/GO_0009714 GO:0009715 biolink:BiologicalProcess chalcone biosynthetic process The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives. go-plus.json chalcone biosynthesis|chalcone anabolism|chalcone synthesis|chalcone formation http://purl.obolibrary.org/obo/GO_0009715 GO:0009716 biolink:BiologicalProcess flavonoid phytoalexin biosynthetic process The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection. go-plus.json flavonoid phytoalexin formation|flavonoid phytoalexin biosynthesis|flavonoid phytoalexin anabolism|flavonoid phytoalexin synthesis http://purl.obolibrary.org/obo/GO_0009716 GO:0009717 biolink:BiologicalProcess isoflavonoid biosynthetic process The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids. go-plus.json isoflavonoid biosynthesis|isoflavonoid synthesis|isoflavonoid formation|isoflavonoid anabolism http://purl.obolibrary.org/obo/GO_0009717 GO:0009718 biolink:BiologicalProcess anthocyanin-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins. go-plus.json anthocyanin biosynthesis|anthocyanin biosynthetic process|anthocyanin anabolism|anthocyanin synthesis|anthocyanin formation http://purl.obolibrary.org/obo/GO_0009718 GO:0009719 biolink:BiologicalProcess response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0009719 gocheck_do_not_manually_annotate|goslim_plant CHEBI:47773 biolink:ChemicalSubstance very-low-density lipoprotein cholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47773 GO:0044130 biolink:BiologicalProcess obsolete negative regulation of growth of symbiont in host OBSOLETE. Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044130 CHEBI:47774 biolink:ChemicalSubstance low-density lipoprotein cholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47774 GO:0010718 biolink:BiologicalProcess positive regulation of epithelial to mesenchymal transition Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010718 CHEBI:47775 biolink:ChemicalSubstance high-density lipoprotein cholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47775 GO:0010719 biolink:BiologicalProcess negative regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010719 CHEBI:47776 biolink:ChemicalSubstance very-low-density lipoprotein triglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_47776 CHEBI:47777 biolink:ChemicalSubstance 1,3-diglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_47777 chebi_ph7_3 CHEBI:47778 biolink:ChemicalSubstance glyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_47778 UBERON:0004945 biolink:AnatomicalEntity submucosa of neck of urinary bladder A submucosa that is part of a neck of urinary bladder [Automatically generated definition]. go-plus.json submucosa of bladder neck|neck of urinary bladder submucosa|submucosa of vesical neck|submucosa of urinary bladder neck|neck of bladder submucosa|bladder neck submucosa|vesical neck submucosa|urinary bladder neck submucosa|submucosa of neck of bladder http://purl.obolibrary.org/obo/UBERON_0004945 CHEBI:47779 biolink:ChemicalSubstance aminoglycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_47779 GO:0044137 biolink:BiologicalProcess obsolete growth of symbiont on or near host rhizosphere OBSOLETE. The increase in size or mass of symbiont occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044137 GO:0010712 biolink:BiologicalProcess regulation of collagen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. go-plus.json regulation of collagen metabolism http://purl.obolibrary.org/obo/GO_0010712 GO:0044138 biolink:BiologicalProcess obsolete modulation of development of symbiont on or near host OBSOLETE. Any process in which the symbiont regulates its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044138 GO:0010713 biolink:BiologicalProcess negative regulation of collagen metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. go-plus.json http://purl.obolibrary.org/obo/GO_0010713 GO:0044135 biolink:BiologicalProcess obsolete growth of symbiont on or near host phyllosphere OBSOLETE. The increase in size or mass of symbiont occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044135 GO:0010710 biolink:BiologicalProcess regulation of collagen catabolic process Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. go-plus.json regulation of collagen degradation|regulation of collagen breakdown|regulation of collagen catabolism http://purl.obolibrary.org/obo/GO_0010710 GO:0010711 biolink:BiologicalProcess negative regulation of collagen catabolic process Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. go-plus.json negative regulation of collagen breakdown|down-regulation of collagen catabolic process|negative regulation of collagen catabolism|downregulation of collagen catabolic process|down regulation of collagen catabolic process|inhibition of collagen catabolic process|negative regulation of collagen degradation http://purl.obolibrary.org/obo/GO_0010711 GO:0044136 biolink:BiologicalProcess obsolete development of symbiont on or near host rhizosphere OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044136 GO:0044133 biolink:BiologicalProcess obsolete growth of symbiont on or near host OBSOLETE. The increase in size or mass of a symbiont within the cells or tissues of its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044133 GO:0010716 biolink:BiologicalProcess negative regulation of extracellular matrix disassembly Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. go-plus.json down-regulation of extracellular matrix disassembly|downregulation of extracellular matrix disassembly|down regulation of extracellular matrix disassembly|inhibition of extracellular matrix disassembly|negative regulation of extracellular matrix degradation|negative regulation of extracellular matrix breakdown http://purl.obolibrary.org/obo/GO_0010716 GO:0044134 biolink:BiologicalProcess obsolete development of symbiont on or near host phyllosphere OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044134 GO:0010717 biolink:BiologicalProcess regulation of epithelial to mesenchymal transition Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010717 GO:0044131 biolink:BiologicalProcess negative regulation of development of symbiont in host Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044131 CHEBI:47771 biolink:ChemicalSubstance beta-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47771 chebi_ph7_3 GO:0010714 biolink:BiologicalProcess positive regulation of collagen metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. go-plus.json positive regulation of collagen metabolism http://purl.obolibrary.org/obo/GO_0010714 CHEBI:47772 biolink:ChemicalSubstance delta-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_47772 chebi_ph7_3 GO:0010715 biolink:BiologicalProcess regulation of extracellular matrix disassembly Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. go-plus.json regulation of extracellular matrix breakdown|regulation of extracellular matrix degradation http://purl.obolibrary.org/obo/GO_0010715 GO:0044132 biolink:BiologicalProcess obsolete development of symbiont on or near host OBSOLETE. The progression of a symbiont from an initial condition to a later condition, within the cells or tissues of its host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044132 CHEBI:33143 biolink:ChemicalSubstance chromic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33143 CHEBI:33144 biolink:ChemicalSubstance hydrogenchromate go-plus.json http://purl.obolibrary.org/obo/CHEBI_33144 CHEBI:33145 biolink:ChemicalSubstance boron oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33145 GO:0009720 biolink:BiologicalProcess detection of hormone stimulus The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of hormone stimulus http://purl.obolibrary.org/obo/GO_0009720 GO:0044139 biolink:BiologicalProcess obsolete modulation of growth of symbiont on or near host OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass on or near the cells or tissues of the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044139 GO:0009721 biolink:BiologicalProcess detection of auxin stimulus The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of auxin stimulus http://purl.obolibrary.org/obo/GO_0009721 GO:0009722 biolink:BiologicalProcess detection of cytokinin stimulus The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of cytokinin stimulus http://purl.obolibrary.org/obo/GO_0009722 GO:0009723 biolink:BiologicalProcess response to ethylene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus. go-plus.json response to ethylene stimulus|response to ethene stimulus http://purl.obolibrary.org/obo/GO_0009723 GO:0009724 biolink:BiologicalProcess detection of abscisic acid stimulus The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of abscisic acid stimulus http://purl.obolibrary.org/obo/GO_0009724 UBERON:0004952 biolink:AnatomicalEntity submucosa of bronchiole A submucosa that is part of a bronchiole [Automatically generated definition]. go-plus.json submucosa of lobular bronchiole|bronchiole submucosa|lobular bronchiole submucosa http://purl.obolibrary.org/obo/UBERON_0004952 GO:0009725 biolink:BiologicalProcess response to hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. go-plus.json response to hormone stimulus|growth regulator http://purl.obolibrary.org/obo/GO_0009725 GO:0009726 biolink:BiologicalProcess detection of endogenous stimulus The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of endogenous stimulus http://purl.obolibrary.org/obo/GO_0009726 UBERON:0004950 biolink:AnatomicalEntity submucosa of lobar bronchus A submucosa that is part of a lobar bronchus [Automatically generated definition]. go-plus.json lobar bronchial submucosa|submucosa of secondary bronchus|lobar bronchus submucosa|secondary bronchus submucosa http://purl.obolibrary.org/obo/UBERON_0004950 GO:0009727 biolink:BiologicalProcess detection of ethylene stimulus The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal. go-plus.json detection of ethene stimulus|perception of ethene stimulus|perception of ethylene stimulus http://purl.obolibrary.org/obo/GO_0009727 GO:0009728 biolink:BiologicalProcess detection of gibberellic acid stimulus The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of gibberellic acid stimulus http://purl.obolibrary.org/obo/GO_0009728 UBERON:0004951 biolink:AnatomicalEntity submucosa of segmental bronchus A submucosa that is part of a segmental bronchus [Automatically generated definition]. go-plus.json segmental bronchus submucosa|submucosa of tertiary bronchus|tertiary bronchus submucosa|segmental bronchial submucosa http://purl.obolibrary.org/obo/UBERON_0004951 CHEBI:33140 biolink:ChemicalSubstance pyrazolium go-plus.json http://purl.obolibrary.org/obo/CHEBI_33140 GO:0009729 biolink:BiologicalProcess detection of brassinosteroid stimulus The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal. go-plus.json perception of brassinosteroid stimulus http://purl.obolibrary.org/obo/GO_0009729 GO:0019184 biolink:BiologicalProcess nonribosomal peptide biosynthetic process The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione. go-plus.json non-ribosomal peptide biosynthesis|non-ribosomal peptide biosynthetic process|non-ribosomal peptide synthesis|non-ribosomal peptide formation|nonribosomal peptide anabolism|nonribosomal peptide biosynthesis|nonribosomal peptide synthesis|nonribosomal peptide formation|nonribosomal peptide synthetase http://purl.obolibrary.org/obo/GO_0019184 GO:0019185 biolink:CellularComponent snRNA-activating protein complex A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters. go-plus.json SNAPc http://purl.obolibrary.org/obo/GO_0019185 GO:0019182 biolink:MolecularActivity histamine-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0019182 CHEBI:72720 biolink:ChemicalSubstance flavonoid oligomer go-plus.json http://purl.obolibrary.org/obo/CHEBI_72720 GO:0019183 biolink:CellularComponent histamine-gated chloride channel complex A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0019183 GO:0019180 biolink:MolecularActivity dTDP-4-amino-4,6-dideoxygalactose transaminase activity Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose. MetaCyc:2.6.1.59-RXN|EC:2.6.1.59|KEGG_REACTION:R04438|RHEA:10368 go-plus.json thymidine diphosphoaminodideoxygalactose aminotransferase activity|dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity|dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity|dTDP-fucosamine aminotransferase activity|thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity http://purl.obolibrary.org/obo/GO_0019180 GO:0019181 biolink:MolecularActivity halohydrin hydrogen-halide-lyase activity Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide. go-plus.json http://purl.obolibrary.org/obo/GO_0019181 CHEBI:72725 biolink:ChemicalSubstance 3-amino-3-deoxy-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_72725 CHEBI:72726 biolink:ChemicalSubstance hydroxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72726 CHEBI:72728 biolink:ChemicalSubstance D-kanosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72728 GO:0019179 biolink:MolecularActivity dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate. EC:2.6.1.33|MetaCyc:2.6.1.33-RXN|RHEA:19085 go-plus.json thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity|TDP-4-oxo-6-deoxy-D-glucose transaminase activity|dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity|TDP-4-keto-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity|dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity|thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity http://purl.obolibrary.org/obo/GO_0019179 GO:0019177 biolink:MolecularActivity dihydroneopterin triphosphate pyrophosphohydrolase activity Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate. MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN|RHEA:25302 go-plus.json http://purl.obolibrary.org/obo/GO_0019177 GO:0019178 biolink:MolecularActivity NADP phosphatase activity Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate. MetaCyc:NADPPHOSPHAT-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0019178 GO:0019175 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019175 GO:0019176 biolink:MolecularActivity dihydroneopterin monophosphate phosphatase activity Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate. RHEA:25306|MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN go-plus.json dihydroneopterin monophosphate dephosphorylase activity http://purl.obolibrary.org/obo/GO_0019176 GO:0019195 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019195 GO:0019196 biolink:MolecularActivity galactosamine transmembrane transporter activity Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative. go-plus.json galactosamine porter activity http://purl.obolibrary.org/obo/GO_0019196 CHEBI:72730 biolink:ChemicalSubstance flavanone glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_72730 GO:0019193 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019193 CHEBI:72732 biolink:ChemicalSubstance 3-amino-3-deoxy-D-glucopyranose(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72732 chebi_ph7_3 GO:0019194 biolink:MolecularActivity sorbose transmembrane transporter activity Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. go-plus.json sorbose porter activity http://purl.obolibrary.org/obo/GO_0019194 GO:0019191 biolink:MolecularActivity cellobiose transmembrane transporter activity Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose. go-plus.json cellobiose permease activity http://purl.obolibrary.org/obo/GO_0019191 GO:0019192 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019192 CHEBI:72735 biolink:ChemicalSubstance lysophosphatidylethanolamine 20:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72735 GO:0019190 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019190 CHEBI:72737 biolink:ChemicalSubstance lysophosphatidylcholine 17:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72737 chebi_ph7_3 CHEBI:72739 biolink:ChemicalSubstance hydroxyisoflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_72739 GO:0019188 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019188 GO:0019189 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019189 GO:0019186 biolink:MolecularActivity acyl-CoA N-acyltransferase activity Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019186 CHEBI:237958 biolink:ChemicalSubstance ({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_237958 GO:0019187 biolink:MolecularActivity beta-1,4-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0019187 GO:0019162 biolink:MolecularActivity pyridoxamine-oxaloacetate transaminase activity Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal. MetaCyc:PYROXALTRANSAM-RXN|KEGG_REACTION:R01713|RHEA:10844|EC:2.6.1.31 go-plus.json pyridoxamine:oxaloacetate aminotransferase activity|pyridoxamine--oxaloacetate aminotransferase activity|pyridoxamine-oxaloacetate aminotransferase activity http://purl.obolibrary.org/obo/GO_0019162 CHEBI:72740 biolink:ChemicalSubstance methoxyisoflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_72740 GO:0019163 biolink:MolecularActivity pyridoxamine-phosphate transaminase activity Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate. RHEA:15877|EC:2.6.1.54|MetaCyc:PYRDAMPTRANS-RXN go-plus.json pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity|pyridoxamine-phosphate aminotransferase activity|pyridoxamine 5'-phosphate transaminase activity|pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)|pyridoxamine phosphate aminotransferase activity http://purl.obolibrary.org/obo/GO_0019163 CHEBI:72741 biolink:ChemicalSubstance 2-arachidonyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72741 GO:0019160 biolink:MolecularActivity NMN nucleosidase activity Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide. RHEA:23140|KEGG_REACTION:R01270|EC:3.2.2.14|MetaCyc:NMNNUCLEOSID-RXN go-plus.json NMNGhase activity|NMNase activity|nicotinamide-nucleotide phosphoribohydrolase activity|NMN glycohydrolase activity|nicotinamide mononucleotidase activity|nicotinamide mononucleotide nucleosidase activity http://purl.obolibrary.org/obo/GO_0019160 GO:0019161 biolink:MolecularActivity diamine transaminase activity Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate. EC:2.6.1.29|MetaCyc:DIAMTRANSAM-RXN|RHEA:18217 go-plus.json amine transaminase activity|diamine:2-oxoglutarate aminotransferase activity|amine-ketoacid transaminase activity|diamine aminotransferase activity|diamine-ketoglutaric transaminase activity http://purl.obolibrary.org/obo/GO_0019161 CHEBI:72744 biolink:ChemicalSubstance 1-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72744 chebi_ph7_3 CHEBI:72745 biolink:ChemicalSubstance (E)-hexadec-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72745 chebi_ph7_3 CHEBI:72748 biolink:ChemicalSubstance 3-amino-3-deoxy-6-O-phosphono-D-glucopyranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72748 chebi_ph7_3 CHEBI:140498 biolink:ChemicalSubstance dihydro-ferroheme d1(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140498 chebi_ph7_3 CHEBI:140497 biolink:ChemicalSubstance 12,18-didecarboxysiroheme(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140497 chebi_ph7_3 CHEBI:140494 biolink:ChemicalSubstance O(3)-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phospho-xylosyl)-L-serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140494 chebi_ph7_3 CHEBI:140495 biolink:ChemicalSubstance O(3)-(beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phospho-xylosyl)-L-serine(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140495 chebi_ph7_3 GO:0034792 biolink:MolecularActivity hypophosphite dioxygenase activity Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2. UM-BBD_reactionID:r1058 go-plus.json http://purl.obolibrary.org/obo/GO_0034792 GO:0034793 biolink:MolecularActivity cyclopropanecarboxylate-CoA ligase activity Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-. UM-BBD_reactionID:r1056 go-plus.json http://purl.obolibrary.org/obo/GO_0034793 GO:0034794 biolink:MolecularActivity cyclopropanecarboxyl-CoA decyclase activity Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA. UM-BBD_reactionID:r1057|EC:5.5.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034794 GO:0034795 biolink:MolecularActivity cyclohexane monooxygenase activity Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O. MetaCyc:RXN-8697|UM-BBD_reactionID:r1059|KEGG_REACTION:R06945|EC:1.14.15.- go-plus.json cyclohexane hydroxylase activity|butane monooxygenase activity http://purl.obolibrary.org/obo/GO_0034795 GO:0034796 biolink:MolecularActivity adipate-CoA ligase activity Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-. UM-BBD_reactionID:r1060 go-plus.json http://purl.obolibrary.org/obo/GO_0034796 GO:0034797 biolink:MolecularActivity fosfomycin 2-glutathione ligase activity Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid. UM-BBD_reactionID:r1073 go-plus.json http://purl.obolibrary.org/obo/GO_0034797 GO:0034798 biolink:MolecularActivity fosfomycin 2-L-cysteine ligase activity Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid. UM-BBD_reactionID:r1074 go-plus.json http://purl.obolibrary.org/obo/GO_0034798 GO:0034799 biolink:MolecularActivity dihydride TNP tautomerase activity Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form). UM-BBD_reactionID:r1070 go-plus.json http://purl.obolibrary.org/obo/GO_0034799 GO:0019159 biolink:MolecularActivity nicotinamide-nucleotide amidase activity Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3. RHEA:12400|EC:3.5.1.42|MetaCyc:NMNAMIDOHYDRO-RXN go-plus.json NMN deamidase activity|nicotinamide mononucleotide amidohydrolase activity|NMN amidohydrolase|nicotinamide-D-ribonucleotide amidohydrolase activity|nicotinamide mononucleotide deamidase activity http://purl.obolibrary.org/obo/GO_0019159 CHEBI:139498 biolink:ChemicalSubstance N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139498 chebi_ph7_3 CHEBI:139499 biolink:ChemicalSubstance N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139499 chebi_ph7_3 GO:0019157 biolink:MolecularActivity obsolete malate oxidase activity OBSOLETE. Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate. go-plus.json malic dehydrogenase II|malic oxidase activity|(S)-malate:oxygen oxidoreductase activity|FAD-dependent malate oxidase activity http://purl.obolibrary.org/obo/GO_0019157 GO:0019158 biolink:MolecularActivity mannokinase activity Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate. RHEA:11028|EC:2.7.1.7|MetaCyc:MANNKIN-RXN go-plus.json ATP:D-mannose 6-phosphotransferase activity|mannokinase (phosphorylating)|D-fructose (D-mannose) kinase activity http://purl.obolibrary.org/obo/GO_0019158 GO:0019155 biolink:MolecularActivity 3-(imidazol-5-yl)lactate dehydrogenase activity Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+. MetaCyc:IMILACTDEHYDROG-RXN|EC:1.1.1.111 go-plus.json imidazol-5-yl lactate dehydrogenase activity|(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019155 GO:0019156 biolink:MolecularActivity isoamylase activity Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins. MetaCyc:RXN-12280|EC:3.2.1.68|MetaCyc:RXN-14380|MetaCyc:3.2.1.68-RXN go-plus.json glycogen alpha-1,6-glucanohydrolase activity|debranching enzyme activity http://purl.obolibrary.org/obo/GO_0019156 GO:0019153 biolink:MolecularActivity protein-disulfide reductase (glutathione) activity Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol. MetaCyc:PRODISULFREDUCT-RXN|EC:1.8.4.2|RHEA:21064 go-plus.json glutaredoxin reductase|protein-disulfide interchange enzyme|protein-disulphide reductase (glutathione) activity|thiol:protein-disulfide oxidoreductase activity|protein disulfide transhydrogenase activity|glutathione:protein-disulfide oxidoreductase activity|protein disulfide reductase (glutathione)|glutathione-insulin transhydrogenase activity|protein-disulfide isomerase/oxidoreductase activity|glutathione-protein disulfide oxidoreductase activity|insulin reductase activity|thiol-protein disulphide oxidoreductase activity|glutathione--insulin transhydrogenase activity|GSH-insulin transhydrogenase activity|reductase, protein disulfide (glutathione) http://purl.obolibrary.org/obo/GO_0019153 GO:0034790 biolink:MolecularActivity 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-. UM-BBD_reactionID:r1043 go-plus.json http://purl.obolibrary.org/obo/GO_0034790 CHEBI:139497 biolink:ChemicalSubstance N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139497 chebi_ph7_3 GO:0019154 biolink:MolecularActivity glycolate dehydrogenase activity Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate. EC:1.1.99.14|MetaCyc:GLYCOLATEDEHYDRO-RXN|KEGG_REACTION:R00476|RHEA:21264 go-plus.json glycolic acid dehydrogenase activity|glycolate oxidoreductase activity|glycolate:acceptor 2-oxidoreductase activity|glycolate:(acceptor) 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019154 GO:0034791 biolink:MolecularActivity isobutylamine N-hydroxylase activity Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O. UM-BBD_reactionID:r1053|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0034791 GO:0019173 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019173 GO:0019174 biolink:MolecularActivity tetrahydrothiophene 1-oxide reductase activity Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor. MetaCyc:THTOREDUCT-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0019174 GO:0019171 biolink:MolecularActivity 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein]. EC:4.2.1.59|MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN|RHEA:13097 go-plus.json 3-hydroxyacyl-[acyl-carrier protein] dehydratase activity|3-hydroxyacyl-ACP dehydratase activity http://purl.obolibrary.org/obo/GO_0019171 GO:0019172 biolink:MolecularActivity glyoxalase III activity Catalysis of the reaction: methylglyoxal + H2O = D-lactate. RHEA:27754|EC:4.2.1.130|MetaCyc:GLYOXIII-RXN go-plus.json (R)-lactate hydro-lyase|D-lactate dehydratase|glutathione-independent glyoxalase activity http://purl.obolibrary.org/obo/GO_0019172 CHEBI:72755 biolink:ChemicalSubstance kanamycin C(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72755 chebi_ph7_3 GO:0019170 biolink:MolecularActivity methylglyoxal reductase (NADH-dependent) activity Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+. EC:1.1.1.78|RHEA:24528|MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN go-plus.json D-lactaldehyde dehydrogenase activity|methylglyoxal reductase activity|(R)-lactaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019170 CHEBI:72756 biolink:ChemicalSubstance kanamycin X(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72756 chebi_ph7_3 CHEBI:72757 biolink:ChemicalSubstance 2'-oxokanamycin(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72757 chebi_ph7_3 CHEBI:72758 biolink:ChemicalSubstance sphinga-4E,8E-dienine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72758 chebi_ph7_3 GO:0034789 biolink:MolecularActivity 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+. UM-BBD_reactionID:r1042 go-plus.json http://purl.obolibrary.org/obo/GO_0034789 GO:0034781 biolink:MolecularActivity N-cyclohexylformamide amidohydrolase activity Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate. UM-BBD_reactionID:r1030 go-plus.json http://purl.obolibrary.org/obo/GO_0034781 GO:0034782 biolink:MolecularActivity dimethylmalonate decarboxylase activity Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2. UM-BBD_reactionID:r1031 go-plus.json http://purl.obolibrary.org/obo/GO_0034782 GO:0034783 biolink:MolecularActivity pivalate-CoA ligase activity Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP. UM-BBD_reactionID:r1032 go-plus.json http://purl.obolibrary.org/obo/GO_0034783 GO:0034784 biolink:MolecularActivity pivalyl-CoA mutase activity Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. EC:5.4.99.-|UM-BBD_reactionID:r1033 go-plus.json http://purl.obolibrary.org/obo/GO_0034784 GO:0034785 biolink:MolecularActivity salicylate 5-hydroxylase activity Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+. MetaCyc:RXN-10446|EC:1.14.13.172|RHEA:35307|UM-BBD_reactionID:r1034 go-plus.json http://purl.obolibrary.org/obo/GO_0034785 GO:0034786 biolink:MolecularActivity 9-fluorenone-3,4-dioxygenase activity Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone. UM-BBD_reactionID:r1039 go-plus.json http://purl.obolibrary.org/obo/GO_0034786 GO:0034787 biolink:MolecularActivity 1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-. UM-BBD_reactionID:r1040 go-plus.json http://purl.obolibrary.org/obo/GO_0034787 CHEBI:140489 biolink:ChemicalSubstance tropomyosin-related kinase B receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_140489 GO:0034788 biolink:MolecularActivity 2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+. UM-BBD_reactionID:r1041 go-plus.json http://purl.obolibrary.org/obo/GO_0034788 GO:0019168 biolink:MolecularActivity 2-octaprenylphenol hydroxylase activity Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O. MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN|RHEA:27790 go-plus.json http://purl.obolibrary.org/obo/GO_0019168 GO:0019166 biolink:MolecularActivity trans-2-enoyl-CoA reductase (NADPH) activity Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+. Reactome:R-HSA-6786720|MetaCyc:TRANSENOYLCOARED-RXN|EC:1.3.1.38|Reactome:R-HSA-6809810|Reactome:R-HSA-8952873|RHEA:33763 go-plus.json acyl-CoA:NADP+ trans-2-oxidoreductase activity|reductase, trans-enoyl coenzyme A|NADPH-dependent trans-2-enoyl-CoA reductase activity http://purl.obolibrary.org/obo/GO_0019166 GO:0019167 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019167 GO:0019164 biolink:MolecularActivity pyruvate synthase activity Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+. MetaCyc:PYRUFLAVREDUCT-RXN|KEGG_REACTION:R01196|EC:1.2.7.1|RHEA:12765 go-plus.json pyruvate:ferredoxin oxidoreductase activity|pyruvate-ferredoxin reductase activity|PFOR|pyruvic-ferredoxin oxidoreductase activity|pyruvate synthetase activity|pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)|pyruvate oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019164 GO:0019165 biolink:MolecularActivity thiamine kinase activity Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate. RHEA:12012|MetaCyc:THIKIN-RXN|EC:2.7.1.89|KEGG_REACTION:R02134 go-plus.json ATP:thiamin phosphotransferase activity|thiamin phosphokinase activity|thiamin kinase (phosphorylating)|ATP:thiamine phosphotransferase activity|thiamin kinase activity http://purl.obolibrary.org/obo/GO_0019165 GO:0034780 biolink:MolecularActivity glyphosate dehydrogenase activity Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-. UM-BBD_reactionID:r0073 go-plus.json http://purl.obolibrary.org/obo/GO_0034780 CHEBI:72750 biolink:ChemicalSubstance neosartoricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72750 chebi_ph7_3 GO:0019140 biolink:MolecularActivity inositol 3-kinase activity Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate. EC:2.7.1.64|MetaCyc:MYO-INOSITOL-1-KINASE-RXN|RHEA:21804 go-plus.json inositol-1-kinase (phosphorylating)|inositol 1-kinase activity|ATP:myo-inositol 1-phosphotransferase activity|myoinositol kinase activity|myo-inositol 1-kinase activity|myo-inositol 3-kinase activity http://purl.obolibrary.org/obo/GO_0019140 CHEBI:72762 biolink:ChemicalSubstance 6-hydroxytryprostatin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_72762 chebi_ph7_3 GO:0019141 biolink:MolecularActivity 2-dehydropantolactone reductase (B-specific) activity Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+. EC:1.1.1.214|MetaCyc:DEHYDROPANTLACRED-RXN go-plus.json (R)-pantolactone:NADP+ oxidoreductase (B-specific)|2-oxopantoyl lactone reductase|ketopantoyl lactone reductase activity|2-ketopantoyl lactone reductase activity|2-dehydropantoyl-lactone reductase (B-specific) activity http://purl.obolibrary.org/obo/GO_0019141 CHEBI:139480 biolink:ChemicalSubstance (+)-O-methylkolavelool go-plus.json http://purl.obolibrary.org/obo/CHEBI_139480 chebi_ph7_3 CHEBI:72763 biolink:ChemicalSubstance fumitremorgin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_72763 chebi_ph7_3 CHEBI:72764 biolink:ChemicalSubstance 12,13-dihydroxyfumitremorgin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_72764 chebi_ph7_3 CHEBI:139481 biolink:ChemicalSubstance 5-chloro-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_139481 CHEBI:72765 biolink:ChemicalSubstance verruculogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_72765 chebi_ph7_3 CHEBI:72766 biolink:ChemicalSubstance fumitremorgin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_72766 chebi_ph7_3 CHEBI:72767 biolink:ChemicalSubstance demethoxyfumitremorgin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_72767 chebi_ph7_3 CHEBI:72768 biolink:ChemicalSubstance aryl hydrocarbon receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_72768 CHEBI:72769 biolink:ChemicalSubstance 2'-oxokanamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72769 GO:0034778 biolink:MolecularActivity 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r1003 go-plus.json http://purl.obolibrary.org/obo/GO_0034778 GO:0034779 biolink:MolecularActivity 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA. UM-BBD_reactionID:r1004 go-plus.json http://purl.obolibrary.org/obo/GO_0034779 CHEBI:140471 biolink:ChemicalSubstance triricinolein go-plus.json http://purl.obolibrary.org/obo/CHEBI_140471 chebi_ph7_3 GO:0034770 biolink:BiologicalProcess histone H4-K20 methylation The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone. go-plus.json histone lysine H4 K20 methylation|histone H4 K20 methylation|histone H4K20me http://purl.obolibrary.org/obo/GO_0034770 GO:0034771 biolink:BiologicalProcess histone H4-K20 monomethylation The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone. go-plus.json histone lysine H4 K20 monomethylation|histone H4 K20 monomethylation http://purl.obolibrary.org/obo/GO_0034771 GO:0034772 biolink:BiologicalProcess histone H4-K20 dimethylation The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone. go-plus.json histone lysine H4 K20 dimethylation|histone H4 K20 dimethylation http://purl.obolibrary.org/obo/GO_0034772 GO:0034773 biolink:BiologicalProcess histone H4-K20 trimethylation The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone. go-plus.json histone lysine H4 K20 trimethylation|histone H4 K20 trimethylation http://purl.obolibrary.org/obo/GO_0034773 GO:0034774 biolink:CellularComponent secretory granule lumen The volume enclosed by the membrane of a secretory granule. go-plus.json http://purl.obolibrary.org/obo/GO_0034774 GO:0034775 biolink:BiologicalProcess glutathione transmembrane transport A process in which glutathione is transported across a membrane. go-plus.json glutathione membrane transport|transmembrane glutathione transport http://purl.obolibrary.org/obo/GO_0034775 GO:0019139 biolink:MolecularActivity cytokinin dehydrogenase activity Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor. EC:1.5.99.12|MetaCyc:PWY-2841|RHEA:13625|MetaCyc:1.5.99.12-RXN go-plus.json 6-N-dimethylallyladenine:acceptor oxidoreductase activity|cytokinin oxidase activity|N6-dimethylallyladenine:(acceptor) oxidoreductase activity|N6-dimethylallyladenine:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019139 GO:0034776 biolink:BiologicalProcess response to histamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. go-plus.json response to histamine stimulus http://purl.obolibrary.org/obo/GO_0034776 GO:0034777 biolink:CellularComponent recycling endosome lumen The volume enclosed by the membranes of a recycling endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0034777 GO:0019137 biolink:MolecularActivity thioglucosidase activity Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar. MetaCyc:RXN-9946|EC:3.2.1.147 go-plus.json sinigrinase activity|sinigrase activity|thioglucoside glucohydrolase activity|myrosinase activity http://purl.obolibrary.org/obo/GO_0019137 GO:0019138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019138 CHEBI:139477 biolink:ChemicalSubstance mogroside go-plus.json http://purl.obolibrary.org/obo/CHEBI_139477 GO:0019135 biolink:MolecularActivity deoxyhypusine monooxygenase activity Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O. MetaCyc:DEOXYHYPUSINE-MONOOXYGENASE-RXN|Reactome:R-HSA-204662|RHEA:14101|EC:1.14.99.29 go-plus.json deoxyhypusine dioxygenase activity|deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)|DOHH activity|deoxyhypusine hydroxylase activity http://purl.obolibrary.org/obo/GO_0019135 CHEBI:139478 biolink:ChemicalSubstance nerylneryl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139478 GO:0019136 biolink:MolecularActivity deoxynucleoside kinase activity Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate. MetaCyc:2.7.1.145-RXN|EC:2.7.1.145|RHEA:12140 go-plus.json ms-dNK|D. melanogaster deoxynucleoside kinase activity|multisubstrate deoxyribonucleoside kinase activity|multispecific deoxynucleoside kinase activity|Ms-dNK activity|multifunctional deoxynucleoside kinase activity|ATP:deoxynucleoside 5'-phosphotransferase activity|Dm-dNK http://purl.obolibrary.org/obo/GO_0019136 CHEBI:139479 biolink:ChemicalSubstance norbaeocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139479 CHEBI:139472 biolink:ChemicalSubstance (4S)-2,3-dehydroleucopelargonidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139472 GO:0019133 biolink:MolecularActivity choline monooxygenase activity Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O. MetaCyc:RXN1F-357|RHEA:17769|EC:1.14.15.7 go-plus.json choline,reduced-ferredoxin:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019133 GO:0019134 biolink:MolecularActivity glucosamine-1-phosphate N-acetyltransferase activity Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+). RHEA:13725|MetaCyc:2.3.1.157-RXN|KEGG_REACTION:R05332|EC:2.3.1.157 go-plus.json acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity|acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0019134 CHEBI:72760 biolink:ChemicalSubstance tryprostatin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_72760 chebi_ph7_3 GO:0019131 biolink:MolecularActivity obsolete tripeptidyl-peptidase I activity OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH. go-plus.json tripeptidyl aminopeptidase activity|tripeptidyl peptidase activity|tripeptidyl-peptidase I activity http://purl.obolibrary.org/obo/GO_0019131 GO:0019132 biolink:MolecularActivity obsolete C-terminal processing peptidase activity OBSOLETE. Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala. go-plus.json protease Re|CtpA gene product (Synechocystis sp.)|Tsp protease|photosystem II D1 protein processing peptidase|tail-specific protease activity|C-terminal processing peptidase activity http://purl.obolibrary.org/obo/GO_0019132 CHEBI:72761 biolink:ChemicalSubstance tryprostatin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_72761 chebi_ph7_3 GO:0019151 biolink:MolecularActivity galactose 1-dehydrogenase activity Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+. EC:1.1.1.48|MetaCyc:GALACTODEHYDROG-RXN|RHEA:21296 go-plus.json D-galactose dehydrogenase activity|NAD-dependent D-galactose dehydrogenase activity|D-galactose:NAD+ 1-oxidoreductase activity|beta-galactose dehydrogenase activity|D-galactose 1-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0019151 GO:0019152 biolink:MolecularActivity acetoin dehydrogenase activity Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+. KEGG_REACTION:R02343|MetaCyc:ACETOINDEHYDROG-RXN|EC:1.1.1.304|EC:1.1.1.303 go-plus.json diacetyl reductase activity http://purl.obolibrary.org/obo/GO_0019152 CHEBI:72775 biolink:ChemicalSubstance methyl benzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72775 chebi_ph7_3 CHEBI:139492 biolink:ChemicalSubstance sensitiser go-plus.json http://purl.obolibrary.org/obo/CHEBI_139492 GO:0019150 biolink:MolecularActivity D-ribulokinase activity Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate. EC:2.7.1.47|RHEA:17601|MetaCyc:D-RIBULOKIN-RXN go-plus.json ATP:D-ribulose 5-phosphotransferase activity|D-ribulokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0019150 CHEBI:72776 biolink:ChemicalSubstance kunzeaol go-plus.json http://purl.obolibrary.org/obo/CHEBI_72776 chebi_ph7_3 CHEBI:139493 biolink:ChemicalSubstance N(4)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc]-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139493 chebi_ph7_3 CHEBI:72777 biolink:ChemicalSubstance 7,8-dihydroneopterin 2'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72777 chebi_ph7_3 CHEBI:72778 biolink:ChemicalSubstance 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72778 chebi_ph7_3 GO:0034767 biolink:BiologicalProcess positive regulation of ion transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. go-plus.json up-regulation of transmembrane ion transport|upregulation of transmembrane ion transport|up regulation of transmembrane ion transport|activation of transmembrane ion transport|positive regulation of transmembrane ion transport|stimulation of transmembrane ion transport|positive regulation of ion membrane transport http://purl.obolibrary.org/obo/GO_0034767 GO:0034768 biolink:MolecularActivity (E)-beta-ocimene synthase activity Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate. EC:4.2.3.106|RHEA:32691|MetaCyc:RXN-5109 go-plus.json http://purl.obolibrary.org/obo/GO_0034768 CHEBI:140466 biolink:ChemicalSubstance hederagenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140466 chebi_ph7_3 GO:0034769 biolink:BiologicalProcess basement membrane disassembly The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. go-plus.json basal lamina disassembly http://purl.obolibrary.org/obo/GO_0034769 GO:0034760 biolink:BiologicalProcess negative regulation of iron ion transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json negative regulation of transmembrane iron ion transport|down-regulation of transmembrane iron ion transport|negative regulation of transmembrane iron transport|downregulation of transmembrane iron ion transport|down regulation of transmembrane iron ion transport|negative regulation of iron ion membrane transport|inhibition of transmembrane iron ion transport http://purl.obolibrary.org/obo/GO_0034760 GO:0034761 biolink:BiologicalProcess positive regulation of iron ion transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json stimulation of transmembrane iron ion transport|positive regulation of transmembrane iron ion transport|up-regulation of transmembrane iron ion transport|activation of transmembrane iron ion transport|up regulation of transmembrane iron ion transport|positive regulation of iron ion membrane transport|positive regulation of transmembrane iron transport|upregulation of transmembrane iron ion transport http://purl.obolibrary.org/obo/GO_0034761 GO:0034762 biolink:BiologicalProcess regulation of transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. go-plus.json regulation of membrane transport http://purl.obolibrary.org/obo/GO_0034762 GO:0034763 biolink:BiologicalProcess negative regulation of transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. go-plus.json down-regulation of transmembrane transport|inhibition of transmembrane transport|negative regulation of membrane transport|down regulation of transmembrane transport|downregulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0034763 GO:0034764 biolink:BiologicalProcess positive regulation of transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. go-plus.json activation of transmembrane transport|stimulation of transmembrane transport|up-regulation of transmembrane transport|upregulation of transmembrane transport|positive regulation of membrane transport|up regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0034764 GO:0034765 biolink:BiologicalProcess regulation of ion transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. go-plus.json regulation of ion membrane transport|regulation of transmembrane ion transport http://purl.obolibrary.org/obo/GO_0034765 CHEBI:140467 biolink:ChemicalSubstance gypsogenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140467 chebi_ph7_3 GO:0034766 biolink:BiologicalProcess negative regulation of ion transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. go-plus.json inhibition of transmembrane ion transport|down regulation of transmembrane ion transport|negative regulation of transmembrane ion transport|downregulation of transmembrane ion transport|negative regulation of ion membrane transport|down-regulation of transmembrane ion transport http://purl.obolibrary.org/obo/GO_0034766 CHEBI:140468 biolink:ChemicalSubstance gypsogenate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140468 chebi_ph7_3 GO:0019148 biolink:MolecularActivity D-cysteine desulfhydrase activity Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate. RHEA:11268|MetaCyc:DCYSDESULF-RXN|EC:4.4.1.15 go-plus.json D-cysteine lyase activity|D-cysteine sulfide-lyase (deaminating; pyruvate-forming)|D-cysteine sulfide-lyase (deaminating) http://purl.obolibrary.org/obo/GO_0019148 GO:0019149 biolink:MolecularActivity 3-chloro-D-alanine dehydrochlorinase activity Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3. EC:4.5.1.2|RHEA:18873|MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN go-plus.json beta-chloro-D-alanine dehydrochlorinase activity|3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)|3-chloro-D-alanine chloride-lyase (deaminating) http://purl.obolibrary.org/obo/GO_0019149 GO:0019146 biolink:MolecularActivity arabinose-5-phosphate isomerase activity Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+). RHEA:23104|KEGG_REACTION:R01530|MetaCyc:DARAB5PISOM-RXN|EC:5.3.1.13 go-plus.json phosphoarabinoisomerase activity|D-arabinose-5-phosphate ketol-isomerase activity|arabinose phosphate isomerase activity|D-arabinose-5-phosphate aldose-ketose-isomerase activity http://purl.obolibrary.org/obo/GO_0019146 GO:0019147 biolink:MolecularActivity (R)-aminopropanol dehydrogenase activity Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH. RHEA:16517|MetaCyc:AMINOPROPDEHYDROG-RXN|KEGG_REACTION:R03759|EC:1.1.1.75 go-plus.json (R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|1-aminopropan-2-ol-NAD+ dehydrogenase activity|DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity|L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity|1-aminopropan-2-ol-dehydrogenase activity|L-aminopropanol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0019147 GO:0019144 biolink:MolecularActivity ADP-sugar diphosphatase activity Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate. EC:3.6.1.21|MetaCyc:ADPSUGPPHOSPHAT-RXN go-plus.json nucleoside diphosphate-sugar hydrolase activity|ADP-sugar sugarphosphohydrolase activity|ADPsugar pyrophosphatase activity|adenosine diphosphosugar pyrophosphatase activity|ADP-sugar pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0019144 GO:0019145 biolink:MolecularActivity aminobutyraldehyde dehydrogenase activity Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+. MetaCyc:AMINOBUTDEHYDROG-RXN|RHEA:19105|EC:1.2.1.19 go-plus.json ABAL dehydrogenase activity|4-aminobutyraldehyde dehydrogenase activity|4-aminobutanal dehydrogenase activity|gamma-aminobutyraldehyde dehydroganase activity|4-aminobutanal:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0019145 GO:0019142 biolink:MolecularActivity 2-hydroxyglutarate synthase activity Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+). MetaCyc:HYDGLUTSYN-RXN|RHEA:19185|KEGG_REACTION:R00932|EC:2.3.3.11 go-plus.json propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)|2-hydroxyglutaric synthetase activity|hydroxyglutarate synthase activity|2-hydroxyglutaratic synthetase activity|2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity|alpha-hydroxyglutarate synthase activity http://purl.obolibrary.org/obo/GO_0019142 CHEBI:72771 biolink:ChemicalSubstance breast cancer resistance protein inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_72771 GO:0019143 biolink:MolecularActivity 3-deoxy-manno-octulosonate-8-phosphatase activity Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate. KEGG_REACTION:R03350|MetaCyc:KDO-8PPHOSPHAT-RXN|EC:3.1.3.45|RHEA:11500 go-plus.json 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0019143 CHEBI:72772 biolink:ChemicalSubstance beta-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72772 CHEBI:72784 biolink:ChemicalSubstance 7,8-dihydroneopterin 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72784 CHEBI:72787 biolink:ChemicalSubstance 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72787 CHEBI:72788 biolink:ChemicalSubstance 7,8-dihydromethanopterin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72788 chebi_ph7_3 GO:0034756 biolink:BiologicalProcess regulation of iron ion transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of Fe transport|regulation of iron ion import|regulation of iron transport|regulation of iron import http://purl.obolibrary.org/obo/GO_0034756 CHEBI:140454 biolink:ChemicalSubstance O-[S-(5-bromopyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140454 chebi_ph7_3 GO:0010789 biolink:BiologicalProcess meiotic sister chromatid cohesion involved in meiosis I The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0010789 GO:0034757 biolink:BiologicalProcess negative regulation of iron ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down-regulation of iron ion transport|negative regulation of iron transport|downregulation of iron ion transport|down regulation of iron ion transport|inhibition of iron ion transport http://purl.obolibrary.org/obo/GO_0034757 CHEBI:140455 biolink:ChemicalSubstance O-[S-(4,5-dibromopyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140455 chebi_ph7_3 GO:0034758 biolink:BiologicalProcess positive regulation of iron ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up-regulation of iron ion transport|activation of iron ion transport|up regulation of iron ion transport|positive regulation of iron transport|upregulation of iron ion transport|stimulation of iron ion transport http://purl.obolibrary.org/obo/GO_0034758 GO:0010787 biolink:BiologicalProcess COPI coating of Golgi vesicle, inter-Golgi cisterna The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat. go-plus.json http://purl.obolibrary.org/obo/GO_0010787 CHEBI:140452 biolink:ChemicalSubstance 1-[(1Z)-octadecenyl]-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140452 chebi_ph7_3 GO:0034759 biolink:BiologicalProcess regulation of iron ion transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json regulation of transmembrane iron ion transport|regulation of iron ion membrane transport|regulation of transmembrane iron transport|regulation of transmembrane Fe transport http://purl.obolibrary.org/obo/GO_0034759 GO:0010788 biolink:BiologicalProcess COPI coating of Golgi vesicle, cis-Golgi to rough ER The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat. go-plus.json http://purl.obolibrary.org/obo/GO_0010788 CHEBI:140451 biolink:ChemicalSubstance N-acyl-1-[(1Z)-alkenyl]-2-acyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140451 chebi_ph7_3 GO:0009792 biolink:BiologicalProcess embryo development ending in birth or egg hatching The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. go-plus.json embryogenesis http://purl.obolibrary.org/obo/GO_0009792 GO:0010781 biolink:BiologicalProcess meiotic DNA double-strand break formation involved in meiotic gene conversion The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. go-plus.json http://purl.obolibrary.org/obo/GO_0010781 GO:0009793 biolink:BiologicalProcess embryo development ending in seed dormancy The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana. go-plus.json embryogenesis http://purl.obolibrary.org/obo/GO_0009793 GO:0010782 biolink:BiologicalProcess proboscis morphogenesis, labial disc-derived The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010782 GO:0009794 biolink:BiologicalProcess regulation of mitotic cell cycle, embryonic Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo. go-plus.json regulation of progression through embryonic mitotic cell cycle|embryonic mitotic cell cycle modulation|regulation of embryonic mitotic cell cycle progression|modulation of embryonic mitotic cell cycle progression|regulation of embryonic mitotic cell cycle|embryonic mitotic cell cycle regulation|embryonic mitotic cell cycle regulator http://purl.obolibrary.org/obo/GO_0009794 GO:0034750 biolink:CellularComponent Scrib-APC-beta-catenin complex A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation. go-plus.json hScrib-APC-beta-catenin complex http://purl.obolibrary.org/obo/GO_0034750 NCBITaxon:93061 biolink:OrganismalEntity Staphylococcus aureus subsp. aureus NCTC 8325 go-plus.json Staphylococcus aureus subsp. aureus str. NCTC 8325|Staphylococcus aureus NCTC 8325|Staphylococcus aureus subsp. aureus strain NCTC 8325 http://purl.obolibrary.org/obo/NCBITaxon_93061 GO:0034751 biolink:CellularComponent aryl hydrocarbon receptor complex A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR. go-plus.json AhR complex|AHRC http://purl.obolibrary.org/obo/GO_0034751 GO:0009795 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009795 GO:0010780 biolink:BiologicalProcess meiotic DNA double-strand break formation involved in reciprocal meiotic recombination The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json http://purl.obolibrary.org/obo/GO_0010780 GO:0019119 biolink:MolecularActivity phenanthrene-9,10-epoxide hydrolase activity Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene. go-plus.json http://purl.obolibrary.org/obo/GO_0019119 GO:0034752 biolink:CellularComponent cytosolic aryl hydrocarbon receptor complex An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP. go-plus.json cytosolic AhR complex|9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex|cytosolic AHRC http://purl.obolibrary.org/obo/GO_0034752 GO:0009796 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009796 GO:0010785 biolink:BiologicalProcess clathrin coating of Golgi vesicle, plasma membrane to endosome targeting The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat. go-plus.json http://purl.obolibrary.org/obo/GO_0010785 GO:0009797 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009797 GO:0010786 biolink:BiologicalProcess clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat. go-plus.json http://purl.obolibrary.org/obo/GO_0010786 GO:0034753 biolink:CellularComponent nuclear aryl hydrocarbon receptor complex An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT). go-plus.json nuclear AHRC|6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex|nuclear AhR complex http://purl.obolibrary.org/obo/GO_0034753 GO:0009798 biolink:BiologicalProcess axis specification The establishment, maintenance and elaboration of a pattern along a line or around a point. go-plus.json axis determination http://purl.obolibrary.org/obo/GO_0009798 GO:0010783 biolink:BiologicalProcess proboscis morphogenesis, eye-antennal disc-derived The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010783 CHEBI:140456 biolink:ChemicalSubstance O-[S-(3,4,5-tribromopyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140456 chebi_ph7_3 GO:0034754 biolink:BiologicalProcess cellular hormone metabolic process The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0034754 GO:0019117 biolink:MolecularActivity dihydroxyfluorene dioxygenase activity Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid. EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0019117 GO:0019118 biolink:MolecularActivity phenanthrene-epoxide hydrolase activity Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene. EC:3.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0019118 GO:0034755 biolink:BiologicalProcess iron ion transmembrane transport A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json iron(2+) transmembrane transport|high affinity iron ion transport|low-affinity iron ion transmembrane transport|transmembrane iron transport|high-affinity ferrous ion transmembrane transport|high-affinity iron ion transport|iron ion membrane transport|low affinity iron ion transport|high-affinity iron ion transmembrane transport|high affinity ferrous ion transmembrane transport|ferrous iron transmembrane transport|ferrous ion transmembrane transport|low-affinity iron ion transport http://purl.obolibrary.org/obo/GO_0034755 GO:0009799 biolink:BiologicalProcess specification of symmetry The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created. go-plus.json determination of symmetry http://purl.obolibrary.org/obo/GO_0009799 GO:0010784 biolink:BiologicalProcess proboscis morphogenesis, clypeo-labral disc-derived The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010784 GO:0019115 biolink:MolecularActivity benzaldehyde dehydrogenase [NAD(P)+] activity Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+. EC:1.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0019115 GO:0019116 biolink:MolecularActivity hydroxy-nicotine oxidase activity Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide. EC:1.5.3.6 go-plus.json http://purl.obolibrary.org/obo/GO_0019116 GO:0019113 biolink:MolecularActivity limonene monooxygenase activity Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene. EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0019113 GO:0019114 biolink:MolecularActivity catechol dioxygenase activity Catalysis of the reaction: catechol + O2 = a muconate. EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0019114 CHEBI:72780 biolink:ChemicalSubstance cobalt-precorrin-6B(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72780 chebi_ph7_3 GO:0019111 biolink:MolecularActivity phenanthrol sulfotransferase activity Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate. go-plus.json phenanthrol sulphotransferase activity http://purl.obolibrary.org/obo/GO_0019111 GO:0019112 biolink:MolecularActivity phenanthrol glycosyltransferase activity Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0019112 CHEBI:72781 biolink:ChemicalSubstance 6-tuliposide A go-plus.json http://purl.obolibrary.org/obo/CHEBI_72781 chebi_ph7_3 CHEBI:72782 biolink:ChemicalSubstance methyl (indol-3-yl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72782 chebi_ph7_3 GO:0019110 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019110 CHEBI:72783 biolink:ChemicalSubstance 12-HHTrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72783 GO:0019130 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019130 CHEBI:72797 biolink:ChemicalSubstance kanamycin X go-plus.json http://purl.obolibrary.org/obo/CHEBI_72797 CHEBI:139471 biolink:ChemicalSubstance (4S)-2,3-dehydroleucocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_139471 CHEBI:72799 biolink:ChemicalSubstance HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72799 GO:0034745 biolink:CellularComponent APC-IQGAP1-Rac1 complex A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0034745 GO:0034746 biolink:CellularComponent APC-IQGAP1-CLIP-170 complex A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0034746 CHEBI:140444 biolink:ChemicalSubstance linoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140444 chebi_ph7_3 GO:0034747 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034747 GO:0010798 biolink:BiologicalProcess regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin. go-plus.json http://purl.obolibrary.org/obo/GO_0010798 CHEBI:140441 biolink:ChemicalSubstance 12-epi-hapalindole U go-plus.json http://purl.obolibrary.org/obo/CHEBI_140441 chebi_ph7_3 GO:0034748 biolink:CellularComponent Par3-APC-KIF3A complex A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0034748 GO:0010799 biolink:BiologicalProcess regulation of peptidyl-threonine phosphorylation Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0010799 CHEBI:140442 biolink:ChemicalSubstance 12-epi-fischerindole U go-plus.json http://purl.obolibrary.org/obo/CHEBI_140442 chebi_ph7_3 GO:0034749 biolink:CellularComponent Scrib-APC complex A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation. go-plus.json hScrib-APC complex http://purl.obolibrary.org/obo/GO_0034749 CHEBI:140440 biolink:ChemicalSubstance hapalindole H go-plus.json http://purl.obolibrary.org/obo/CHEBI_140440 chebi_ph7_3 GO:0010792 biolink:BiologicalProcess DNA double-strand break processing involved in repair via single-strand annealing The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing. go-plus.json http://purl.obolibrary.org/obo/GO_0010792 GO:0010793 biolink:BiologicalProcess regulation of mRNA export from nucleus Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0010793 GO:0010790 biolink:BiologicalProcess meiotic sister chromatid cohesion involved in meiosis II The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II. go-plus.json http://purl.obolibrary.org/obo/GO_0010790 GO:0010791 biolink:BiologicalProcess DNA double-strand break processing involved in repair via synthesis-dependent strand annealing The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing. go-plus.json http://purl.obolibrary.org/obo/GO_0010791 GO:0034740 biolink:CellularComponent TFIIIC-TOP1-SUB1 complex A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III. go-plus.json TFIIIC-Topoisomerase 1-PC4 complex http://purl.obolibrary.org/obo/GO_0034740 GO:0010796 biolink:BiologicalProcess regulation of multivesicular body size Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0010796 GO:0034741 biolink:CellularComponent APC-tubulin-IQGAP1 complex A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization. go-plus.json 60S APC complex http://purl.obolibrary.org/obo/GO_0034741 GO:0034742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034742 GO:0010797 biolink:BiologicalProcess regulation of multivesicular body size involved in endosome transport Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles. go-plus.json http://purl.obolibrary.org/obo/GO_0010797 CHEBI:140445 biolink:ChemicalSubstance alpha-linolenoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140445 chebi_ph7_3 GO:0019128 biolink:BiologicalProcess peptidyl-tryptophan racemization The racemization of peptidyl-tryptophan. RESID:AA0198 go-plus.json http://purl.obolibrary.org/obo/GO_0019128 GO:0034743 biolink:CellularComponent APC-IQGAP complex A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0034743 GO:0010794 biolink:BiologicalProcess regulation of dolichol biosynthetic process Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units. go-plus.json http://purl.obolibrary.org/obo/GO_0010794 GO:0010795 biolink:BiologicalProcess regulation of ubiquinone biosynthetic process Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0010795 GO:0019129 biolink:BiologicalProcess peptidyl-leucine racemization The racemization of peptidyl-leucine. RESID:AA0197 go-plus.json http://purl.obolibrary.org/obo/GO_0019129 GO:0034744 biolink:CellularComponent APC-IQGAP1-Cdc42 complex A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0034744 CHEBI:140446 biolink:ChemicalSubstance ricinoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_140446 chebi_ph7_3 GO:0019126 biolink:BiologicalProcess peptidyl-serine racemization The racemization of peptidyl-serine. RESID:AA0195 go-plus.json http://purl.obolibrary.org/obo/GO_0019126 GO:0019127 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019127 GO:0019124 biolink:BiologicalProcess peptidyl-isoleucine racemization The racemization of peptidyl-isoleucine. RESID:AA0192 go-plus.json http://purl.obolibrary.org/obo/GO_0019124 GO:0019125 biolink:BiologicalProcess peptidyl-phenylalanine racemization The racemization of peptidyl-phenylalanine. RESID:AA0194 go-plus.json http://purl.obolibrary.org/obo/GO_0019125 CHEBI:72790 biolink:ChemicalSubstance hydroxydocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72790 GO:0019122 biolink:BiologicalProcess peptidyl-D-alanine racemization The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine. RESID:AA0191 go-plus.json alanine racemization http://purl.obolibrary.org/obo/GO_0019122 GO:0019123 biolink:BiologicalProcess peptidyl-methionine racemization The racemization of peptidyl-methionine. RESID:AA0193 go-plus.json http://purl.obolibrary.org/obo/GO_0019123 GO:0019120 biolink:MolecularActivity hydrolase activity, acting on acid halide bonds, in C-halide compounds Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage. EC:3.8.1.-|Reactome:R-HSA-9011595 go-plus.json http://purl.obolibrary.org/obo/GO_0019120 CHEBI:72793 biolink:ChemicalSubstance HETrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72793 GO:0019121 biolink:BiologicalProcess peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan. RESID:AA0218 go-plus.json http://purl.obolibrary.org/obo/GO_0019121 CHEBI:23711 biolink:ChemicalSubstance diethyl 2-methyl-3-hydroxysuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23711 chebi_ph7_3 UBERON:0014393 biolink:AnatomicalEntity sweat of axilla Sweat that is produced by the glands of the axilla. go-plus.json axillary sweat http://purl.obolibrary.org/obo/UBERON_0014393 UBERON:0014394 biolink:AnatomicalEntity uterine fat pad Encapsulated adipose tissue associated with the uterus go-plus.json periuterine fat pad|uterine fat depot|peri-uterine fat pad http://purl.obolibrary.org/obo/UBERON_0014394 UBERON:0014395 biolink:AnatomicalEntity proximal mesopodial bone A proximal mesopodial endochondral element that is composed primarily of a bone tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014395 CHEBI:23700 biolink:ChemicalSubstance dichlorohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23700 UBERON:0014398 biolink:AnatomicalEntity respiratory muscle Muscle that is part of the respiratory system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014398 UBERON:0014399 biolink:AnatomicalEntity sinusoidal space A anatomical space that is enclosed by a sinusoid. go-plus.json lumen of sinusoid|sinusoid lumen http://purl.obolibrary.org/obo/UBERON_0014399 CHEBI:23702 biolink:ChemicalSubstance dichlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23702 CHEBI:23703 biolink:ChemicalSubstance dideoxyhexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23703 GO:0019098 biolink:BiologicalProcess reproductive behavior The specific behavior of an organism that is associated with reproduction. go-plus.json multi-organism reproductive behavior|reproductive behavior in a multicellular organism|reproductive behaviour|multicellular organism reproductive behavior|single-organism reproductive behavior http://purl.obolibrary.org/obo/GO_0019098 goslim_drosophila GO:0019099 biolink:BiologicalProcess female germ-line sex determination The determination of sex and sexual phenotype in a female organism's germ line. go-plus.json sex determination, female germ-line determination http://purl.obolibrary.org/obo/GO_0019099 GO:0019085 biolink:BiologicalProcess early viral transcription The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell. go-plus.json immediate early viral mRNA transcription http://purl.obolibrary.org/obo/GO_0019085 GO:0019086 biolink:BiologicalProcess late viral transcription The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins. go-plus.json late viral mRNA transcription http://purl.obolibrary.org/obo/GO_0019086 GO:0019083 biolink:BiologicalProcess viral transcription The process by which a viral genome, or part of a viral genome, is transcribed within the host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0019083 GO:0019084 biolink:BiologicalProcess middle viral transcription The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication. go-plus.json (delayed) early viral mRNA transcription http://purl.obolibrary.org/obo/GO_0019084 GO:0019081 biolink:BiologicalProcess viral translation A process by which viral mRNA is translated into viral protein, using the host cellular machinery. go-plus.json viral protein biosynthetic process|viral protein anabolism|viral protein synthesis|viral protein biosynthesis|viral protein formation http://purl.obolibrary.org/obo/GO_0019081 CHEBI:72700 biolink:ChemicalSubstance 2-oxopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72700 GO:0019082 biolink:BiologicalProcess viral protein processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein. go-plus.json http://purl.obolibrary.org/obo/GO_0019082 CHEBI:72701 biolink:ChemicalSubstance 2-oxopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72701 chebi_ph7_3 GO:0019080 biolink:BiologicalProcess viral gene expression A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation. go-plus.json viral genome expression http://purl.obolibrary.org/obo/GO_0019080 CHEBI:72704 biolink:ChemicalSubstance chromenyliums go-plus.json http://purl.obolibrary.org/obo/CHEBI_72704 CHEBI:72705 biolink:ChemicalSubstance cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72705 CHEBI:72707 biolink:ChemicalSubstance (2S)-versicolorone go-plus.json http://purl.obolibrary.org/obo/CHEBI_72707 GO:0019078 biolink:BiologicalProcess obsolete lytic viral budding OBSOLETE. A form of viral release in which the viral particles bud out through cellular membranes, resulting in cell lysis. It is also a form of viral envelopment. go-plus.json lytic viral budding http://purl.obolibrary.org/obo/GO_0019078 GO:0019079 biolink:BiologicalProcess viral genome replication Any process involved directly in viral genome replication, including viral nucleotide metabolism. go-plus.json sigma virus replication|viral replication http://purl.obolibrary.org/obo/GO_0019079 GO:0019076 biolink:BiologicalProcess viral release from host cell The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane. VZ:1076 go-plus.json virus exit from host cell|viral exit|viral release|release of virus from host|viral shedding http://purl.obolibrary.org/obo/GO_0019076 GO:0019077 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019077 GO:0019096 biolink:BiologicalProcess pole plasm mitochondrial lrRNA localization Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. go-plus.json oocyte pole plasm mitochondrial lrRNA localization|pole plasm mitochondrial lrRNA localisation|establishment and maintenance of mitochondrial lrRNA localization in pole plasm http://purl.obolibrary.org/obo/GO_0019096 GO:0019097 biolink:BiologicalProcess pole plasm mitochondrial srRNA localization Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. go-plus.json oocyte pole plasm mitochondrial srRNA localization|pole plasm mitochondrial srRNA localisation|establishment and maintenance of mitochondrial localization in pole plasm http://purl.obolibrary.org/obo/GO_0019097 GO:0019094 biolink:BiologicalProcess pole plasm mRNA localization Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. go-plus.json pole plasm mRNA localisation|pole granule RNA localization|oocyte pole plasm mRNA localization|establishment and maintenance of mRNA localization in pole plasm|establishment and maintenance of pole plasm mRNA localization http://purl.obolibrary.org/obo/GO_0019094 GO:0019095 biolink:BiologicalProcess pole plasm mitochondrial rRNA localization Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. go-plus.json establishment and maintenance of mitochondrial rRNA localization in pole plasm|pole plasm mitochondrial rRNA localisation|oocyte pole plasm mitochondrial rRNA localization http://purl.obolibrary.org/obo/GO_0019095 GO:0019092 biolink:BiologicalProcess mitochondrial srRNA export from mitochondrion The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol. go-plus.json mitochondrial srRNA export from mitochondria|mitochondrial srRNA transport from mitochondrion|mitochondrial srRNA, mitochondrial export|export of mitochondrial srRNA|mitochondrial srRNA export out of mitochondrion|mitochondrial srRNA export http://purl.obolibrary.org/obo/GO_0019092 GO:0019093 biolink:BiologicalProcess mitochondrial RNA localization Any process in which mitochondrial RNA is transported to, or maintained in, a specific location. go-plus.json mtRNA localization|establishment and maintenance of mitochondrial RNA localization|mitochondrial RNA localisation http://purl.obolibrary.org/obo/GO_0019093 GO:0019090 biolink:BiologicalProcess mitochondrial rRNA export from mitochondrion The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol. go-plus.json mitochondrial rRNA export out of mitochondrion|export of mitochondrial rRNA|mitochondrial rRNA transport from mitochondrion|mitochondrial rRNA export|mitochondrial rRNA, mitochondrial export|mitochondrial rRNA export from mitochondria http://purl.obolibrary.org/obo/GO_0019090 GO:0019091 biolink:BiologicalProcess mitochondrial lrRNA export from mitochondrion The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol. go-plus.json mitochondrial lrRNA export out of mitochondrion|mitochondrial lrRNA transport from mitochondrion|mitochondrial lrRNA export|mitochondrial lrRNA, mitochondrial export|export of mitochondrial lrRNA|mitochondrial lrRNA export from mitochondria http://purl.obolibrary.org/obo/GO_0019091 CHEBI:72714 biolink:ChemicalSubstance tetracosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72714 CHEBI:72718 biolink:ChemicalSubstance N-dodecanoylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72718 GO:0019089 biolink:BiologicalProcess obsolete transmission of virus OBSOLETE. The transfer of virions in order to create new infection. go-plus.json viral transmission http://purl.obolibrary.org/obo/GO_0019089 GO:0019087 biolink:BiologicalProcess transformation of host cell by virus A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Wikipedia:Viral_transformation go-plus.json viral transformation of host cell|host cell transformation|immortalization of host cell by virus|host cell immortalization|transformation of host cell|immortalization of host cell|viral transformation|viral immortalization http://purl.obolibrary.org/obo/GO_0019087 GO:0019088 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019088 CHEBI:47762 biolink:ChemicalSubstance phosphoethanolamine-Kdo2-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_47762 CHEBI:47763 biolink:ChemicalSubstance beta-L-Ara4N-lipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_47763 GO:0044020 biolink:MolecularActivity histone methyltransferase activity (H4-R3 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4. go-plus.json histone-arginine N-methyltransferase activity (H4-R3 specific)|histone methylase activity (H4-R3 specific) http://purl.obolibrary.org/obo/GO_0044020 CHEBI:23796 biolink:ChemicalSubstance diiodotyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23796 CHEBI:23793 biolink:ChemicalSubstance dihydroxypyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23793 CHEBI:23798 biolink:ChemicalSubstance dimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23798 GO:0044027 biolink:BiologicalProcess hypermethylation of CpG island An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. go-plus.json DNA hypermethylation of CpG island http://purl.obolibrary.org/obo/GO_0044027 CHEBI:33118 biolink:ChemicalSubstance boric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33118 chebi_ph7_3 GO:0044028 biolink:BiologicalProcess DNA hypomethylation An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0044028 GO:0044025 biolink:MolecularActivity histone kinase activity (H2B-S14 specific) Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B. go-plus.json histone-serine kinase activity (H2B-S14 specific)|histone serine kinase activity (H2B-S14 specific) http://purl.obolibrary.org/obo/GO_0044025 GO:0044026 biolink:BiologicalProcess DNA hypermethylation An increase in the epigenetic methylation of cytosine and adenosine residues in DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0044026 GO:0044023 biolink:MolecularActivity histone kinase activity (H4-S1 specific) Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4. go-plus.json histone-serine kinase activity (H4-S1 specific)|histone serine kinase activity (H4-S1 specific) http://purl.obolibrary.org/obo/GO_0044023 GO:0044024 biolink:MolecularActivity histone kinase activity (H2A-S1 specific) Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A. go-plus.json histone serine kinase activity (H2A-S1 specific)|histone-serine kinase activity (H2A-S1 specific) http://purl.obolibrary.org/obo/GO_0044024 CHEBI:23792 biolink:ChemicalSubstance dihydroxypteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23792 GO:0044021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044021 GO:0044022 biolink:MolecularActivity histone kinase activity (H3-S28 specific) Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3. go-plus.json histone serine kinase activity (H3-S28 specific)|histone-serine kinase activity (H3-S28 specific) http://purl.obolibrary.org/obo/GO_0044022 CHEBI:33113 biolink:ChemicalSubstance tetrathionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33113 CHEBI:33114 biolink:ChemicalSubstance disulfane go-plus.json http://purl.obolibrary.org/obo/CHEBI_33114 chebi_ph7_3 GO:0044029 biolink:BiologicalProcess hypomethylation of CpG island An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. go-plus.json DNA hypomethylation of CpG island http://purl.obolibrary.org/obo/GO_0044029 GO:0009709 biolink:BiologicalProcess terpenoid indole alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate). go-plus.json terpenoid indole alkaloid biosynthesis|terpenoid indole alkaloid anabolism|terpenoid indole alkaloid synthesis|terpenoid indole alkaloid formation http://purl.obolibrary.org/obo/GO_0009709 GO:0044030 biolink:BiologicalProcess regulation of DNA methylation Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0044030 GO:0044031 biolink:BiologicalProcess obsolete modification by symbiont of host protein by phosphorylation OBSOLETE. The process in which an organism adds a phosphate group to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044031 GO:0044038 biolink:BiologicalProcess cell wall macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall. go-plus.json cell wall macromolecule biosynthesis|cell wall macromolecule anabolism|cell wall macromolecule synthesis|cell wall macromolecule biosynthetic process at cellular level|cellular cell wall macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0044038 GO:0044039 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044039 GO:0044036 biolink:BiologicalProcess cell wall macromolecule metabolic process The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. go-plus.json cellular cell wall macromolecule metabolic process|cellular cell wall macromolecule metabolism http://purl.obolibrary.org/obo/GO_0044036 GO:0044037 biolink:BiologicalProcess obsolete multi-organism cell wall macromolecule metabolic process OBSOLETE. The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. go-plus.json multi-organism cell wall macromolecule metabolism http://purl.obolibrary.org/obo/GO_0044037 GO:0044034 biolink:BiologicalProcess obsolete multi-organism biosynthetic process OBSOLETE. A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism. go-plus.json multi-organism biosynthesis|multi-organismal biosynthesis|multi-organismal biosynthetic process http://purl.obolibrary.org/obo/GO_0044034 GO:0044035 biolink:BiologicalProcess obsolete multi-organism catabolic process OBSOLETE. A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism. go-plus.json multi-organismal catabolic process|multi-organism catabolism|multi-organismal catabolism http://purl.obolibrary.org/obo/GO_0044035 GO:0044032 biolink:BiologicalProcess modulation by symbiont of indole acetic acid levels in host The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of IAA levels in host|modulation by symbiont of auxin levels in host http://purl.obolibrary.org/obo/GO_0044032 GO:0044033 biolink:BiologicalProcess obsolete multi-organism metabolic process OBSOLETE. A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism. go-plus.json multi-organism metabolism|multi-organismal metabolism|multi-organismal metabolic process http://purl.obolibrary.org/obo/GO_0044033 GO:0009700 biolink:BiologicalProcess indole phytoalexin biosynthetic process The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response. go-plus.json indole phytoalexin biosynthesis|indole phytoalexin anabolism|indole phytoalexin synthesis|indole phytoalexin formation http://purl.obolibrary.org/obo/GO_0009700 GO:0009701 biolink:BiologicalProcess isoflavonoid phytoalexin biosynthetic process The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection. go-plus.json isoflavonoid phytoalexin biosynthesis|isoflavonoid phytoalexin anabolism|isoflavonoid phytoalexin synthesis|isoflavonoid phytoalexin formation http://purl.obolibrary.org/obo/GO_0009701 GO:0009702 biolink:MolecularActivity L-arabinokinase activity Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+). KEGG_REACTION:R01754|EC:2.7.1.46|RHEA:20153|MetaCyc:L-ARABINOKINASE-RXN go-plus.json L-arabinokinase (phosphorylating)|ATP:L-arabinose 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0009702 GO:0009703 biolink:MolecularActivity nitrate reductase (NADH) activity Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+. RHEA:17913|MetaCyc:NITRATE-REDUCTASE-NADH-RXN|EC:1.7.1.1 go-plus.json assimilatory NADH: nitrate reductase activity|assimilatory nitrate reductase activity|assimilatory NADH:nitrate reductase activity|NADH:nitrate reductase activity|NADH:nitrate oxidoreductase activity|nitrite:NAD+ oxidoreductase activity|NADH-dependent nitrate reductase activity|nitrate reductase (NADH(2)) activity|NADH-nitrate reductase activity|nitrate reductase (NADH2) http://purl.obolibrary.org/obo/GO_0009703 GO:0009704 biolink:BiologicalProcess de-etiolation The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll. go-plus.json http://purl.obolibrary.org/obo/GO_0009704 GO:0009705 biolink:CellularComponent plant-type vacuole membrane The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana. go-plus.json tonoplast|membrane of vacuole with cell cycle-independent morphology|vacuolar membrane http://purl.obolibrary.org/obo/GO_0009705 GO:0009706 biolink:CellularComponent chloroplast inner membrane The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma. go-plus.json chloroplast inner envelope http://purl.obolibrary.org/obo/GO_0009706 CHEBI:1372 biolink:ChemicalSubstance 1-pyrroline-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1372 GO:0009707 biolink:CellularComponent chloroplast outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope. go-plus.json chloroplast outer envelope http://purl.obolibrary.org/obo/GO_0009707 GO:0009708 biolink:BiologicalProcess benzyl isoquinoline alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings. go-plus.json benzyl isoquinoline alkaloid anabolism|benzyl isoquinoline alkaloid synthesis|benzyl isoquinoline alkaloid biosynthesis|benzyl isoquinoline alkaloid formation http://purl.obolibrary.org/obo/GO_0009708 GO:0044041 biolink:BiologicalProcess obsolete multi-organism carbohydrate catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism. go-plus.json multi-organism carbohydrate degradation|multi-organism carbohydrate breakdown|multi-organism carbohydrate catabolism http://purl.obolibrary.org/obo/GO_0044041 GO:0044042 biolink:BiologicalProcess glucan metabolic process The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. go-plus.json glucan metabolism http://purl.obolibrary.org/obo/GO_0044042 GO:0044040 biolink:BiologicalProcess obsolete multi-organism carbohydrate metabolic process OBSOLETE. The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism. go-plus.json main pathways of carbohydrate metabolic process|main pathways of carbohydrate metabolism|multi-organism carbohydrate metabolism http://purl.obolibrary.org/obo/GO_0044040 CHEBI:23778 biolink:ChemicalSubstance dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23778 CHEBI:23775 biolink:ChemicalSubstance dihydroxy-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23775 CHEBI:23776 biolink:ChemicalSubstance dihydroxyacetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23776 GO:0044049 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type VI secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type VI secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044049 GO:0044047 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type I secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type I secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044047 GO:0044048 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type V secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type V secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044048 GO:0044045 biolink:BiologicalProcess obsolete interaction with host via substance in symbiont cell outer membrane OBSOLETE. An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044045 GO:0044046 biolink:BiologicalProcess obsolete interaction with host via substance released outside of symbiont OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis. go-plus.json interaction with host via substance released outside of symbiont cells http://purl.obolibrary.org/obo/GO_0044046 GO:0044043 biolink:BiologicalProcess obsolete multi-organism glucan metabolic process OBSOLETE. The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, involving more than one organism. go-plus.json multi-organism glucan metabolism http://purl.obolibrary.org/obo/GO_0044043 GO:0044044 biolink:BiologicalProcess obsolete interaction with host via substance in symbiont surface OBSOLETE. An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044044 GO:0044052 biolink:BiologicalProcess obsolete interaction with host via substance released by membrane budding OBSOLETE. An interaction with the host organism mediated by a substance released via symbiont membrane budding, the evagination of a membrane resulting in formation of a vesicle. go-plus.json interaction with host via substance released by symbiont membrane budding http://purl.obolibrary.org/obo/GO_0044052 GO:0044053 biolink:BiologicalProcess translocation of peptides or proteins into host cell cytoplasm The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm. go-plus.json transport of peptides or proteins into host cell cytoplasm|translocation of symbiont peptides or proteins into host cell cytoplasm http://purl.obolibrary.org/obo/GO_0044053 GO:0044050 biolink:BiologicalProcess obsolete interaction with host via substance released by sporangium lysis OBSOLETE. An interaction with the host organism mediated by a substance released via rupture of symbiont sporangia, structures producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host via substance released by lysis of symbiont sporangium|interaction with host via substance released by sporangia lysis http://purl.obolibrary.org/obo/GO_0044050 GO:0044051 biolink:BiologicalProcess obsolete interaction with host via substance released by symbiont cytolysis OBSOLETE. An interaction with the host organism mediated by a substance released via cytolysis of symbiont cells. Cytolysis is the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host via substance released by cytolysis of symbiont http://purl.obolibrary.org/obo/GO_0044051 CHEBI:23783 biolink:ChemicalSubstance naphthalenediols go-plus.json http://purl.obolibrary.org/obo/CHEBI_23783 GO:0044058 biolink:BiologicalProcess regulation of digestive system process Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044058 GO:0044059 biolink:BiologicalProcess modulation by symbiont of host endocrine process The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism. go-plus.json regulation by symbiont of host endocrine process http://purl.obolibrary.org/obo/GO_0044059 GO:0044056 biolink:BiologicalProcess modulation by symbiont of host digestive system process The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. go-plus.json regulation by symbiont of host digestive system process http://purl.obolibrary.org/obo/GO_0044056 GO:0044057 biolink:BiologicalProcess regulation of system process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. go-plus.json http://purl.obolibrary.org/obo/GO_0044057 CHEBI:23781 biolink:ChemicalSubstance dihydroxyindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_23781 GO:0044054 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044054 GO:0044055 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044055 UBERON:0004990 biolink:AnatomicalEntity mucosa of ascending colon A mucosa that is part of an ascending colon [Automatically generated definition]. go-plus.json mucous membrane of ascending colon|ascending colon mucosa|mucosa of organ of ascending colon|organ mucosa of ascending colon|ascending colon mucosa of organ|ascending colon organ mucosa|ascending colon mucous membrane http://purl.obolibrary.org/obo/UBERON_0004990 UBERON:0004991 biolink:AnatomicalEntity mucosa of transverse colon A mucosa that is part of a transverse colon [Automatically generated definition]. go-plus.json transverse colon mucous membrane|organ mucosa of transverse colon|transverse colon organ mucosa|mucosa of organ of transverse colon|transverse colon mucosa|mucous membrane of transverse colon|transverse colon mucosa of organ http://purl.obolibrary.org/obo/UBERON_0004991 CHEBI:33101 biolink:ChemicalSubstance nitrogen dioxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_33101 chebi_ph7_3 UBERON:0004998 biolink:AnatomicalEntity mucosa of pylorus A mucosa that is part of a pylorus [Automatically generated definition]. go-plus.json stomach pyloric region mucosa of organ|organ mucosa of pyloric part of stomach|pyloric part of stomach mucosa of organ|stomach pyloric region mucous membrane|pylorus organ mucosa|pyloric part of stomach mucous membrane|pylorus mucosa of organ|organ mucosa of pylorus|organ mucosa of stomach pyloric region|pyloric part of stomach organ mucosa|pylorus mucous membrane|stomach pyloric region organ mucosa|antropyloric mucosa|mucous membrane of pyloric part of stomach|mucosa of pyloric part of stomach|pylorus mucosa|mucosa of organ of pyloric part of stomach|mucosa of organ of stomach pyloric region|mucous membrane of pylorus|mucosa of stomach pyloric region|mucous membrane of stomach pyloric region|pyloric part of stomach mucosa|stomach pyloric region mucosa|mucosa of organ of pylorus http://purl.obolibrary.org/obo/UBERON_0004998 UBERON:0004999 biolink:AnatomicalEntity mucosa of biliary tree A mucosa that is part of a biliary tree [Automatically generated definition]. go-plus.json organ mucosa of biliary tree|mucous membrane of biliary tract|mucosa of biliary tract|biliary tract mucosa|mucosa of organ of biliary tree|mucosa of organ of biliary tract|biliary tree mucosa|mucous membrane of biliary tree|biliary tree mucosa of organ|organ mucosa of biliary tract|biliary tract mucosa of organ|biliary tree mucous membrane|biliary tract mucous membrane|biliary tract organ mucosa|biliary tree organ mucosa http://purl.obolibrary.org/obo/UBERON_0004999 UBERON:0004997 biolink:AnatomicalEntity mucosa of pyloric antrum A mucosa that is part of a pyloric antrum [Automatically generated definition]. go-plus.json mucosa of organ of pyloric antrum|mucous membrane of antrum of stomach|mucosa of antrum of stomach|pyloric antrum organ mucosa|mucous membrane of pyloric antrum|antral mucosa|mucosa of organ of antrum of stomach|mucosa of organ of stomach pyloric antrum|gastric antrum mucosa|pyloric antrum mucosa of organ|mucosa of stomach pyloric antrum|antrum of stomach mucosa|stomach pyloric antrum mucosa|mucous membrane of stomach pyloric antrum|pyloric antrum mucous membrane|stomach pyloric antrum mucosa of organ|organ mucosa of antrum of stomach|antrum of stomach mucosa of organ|pyloric antrum mucosa|organ mucosa of pyloric antrum|stomach pyloric antrum mucous membrane|antrum of stomach mucous membrane|organ mucosa of stomach pyloric antrum|antrum of stomach organ mucosa|stomach pyloric antrum organ mucosa http://purl.obolibrary.org/obo/UBERON_0004997 UBERON:0004995 biolink:AnatomicalEntity mucosa of body of stomach A mucosa that is part of a body of stomach [Automatically generated definition]. go-plus.json mucous membrane of body of stomach|gastric body mucous membrane|gastric body mucosa|corpus gastricum (ventriculare) mucosa of organ|organ mucosa of corpus gastricum (ventriculare)|mucosa of organ of body of stomach|organ mucosa of gastric body|corpus gastricum (ventriculare) mucous membrane|mucosa of organ of stomach body|corpus gastricum (ventriculare) organ mucosa|stomach body mucosa|body of stomach mucosa|mucosa of stomach body|mucous membrane of stomach body|body of stomach mucosa of organ|organ mucosa of body of stomach|stomach body mucosa of organ|gastric body organ mucosa|mucous membrane of corpus gastricum (ventriculare)|mucosa of organ of gastric body|mucosa of corpus gastricum (ventriculare)|body of stomach mucous membrane|mucosa of gastric body|stomach body mucous membrane|mucosa of organ of corpus gastricum (ventriculare)|mucous membrane of gastric body|corpus gastricum (ventriculare) mucosa|gastric body mucosa of organ|stomach body organ mucosa|body of stomach organ mucosa|organ mucosa of stomach body http://purl.obolibrary.org/obo/UBERON_0004995 UBERON:0004992 biolink:AnatomicalEntity mucosa of descending colon A mucosa that is part of a descending colon [Automatically generated definition]. go-plus.json organ mucosa of descending colon|descending colon mucosa|mucosa of organ of descending colon|mucous membrane of descending colon|descending colon mucosa of organ|descending colon organ mucosa|descending colon mucous membrane http://purl.obolibrary.org/obo/UBERON_0004992 UBERON:0004993 biolink:AnatomicalEntity mucosa of sigmoid colon A mucosa that is part of a sigmoid colon [Automatically generated definition]. go-plus.json sigmoid colon mucous membrane|sigmoid colon organ mucosa|mucous membrane of sigmoid colon|mucosa of organ of sigmoid colon|sigmoid colon mucosa|sigmoid colon mucosa of organ|organ mucosa of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0004993 UBERON:0014382 biolink:AnatomicalEntity collection of hairs on head or neck A collection of hairs that is part of a craniocervical region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0014382 GO:0044063 biolink:BiologicalProcess modulation by symbiont of host nervous system process The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system. go-plus.json modulation by symbiont of host neurological system process|regulation by symbiont of host neurological system process http://purl.obolibrary.org/obo/GO_0044063 GO:0044064 biolink:BiologicalProcess modulation by symbiont of host respiratory system process The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. go-plus.json regulation by symbiont of host respiratory system process http://purl.obolibrary.org/obo/GO_0044064 GO:0044061 biolink:BiologicalProcess modulation by symbiont of host excretion The alteration by a symbiont organism of the functioning of excretion, the elimination by the host organism of the waste products that arise as a result of metabolic activity. go-plus.json regulation by symbiont of host excretion http://purl.obolibrary.org/obo/GO_0044061 CHEBI:23750 biolink:ChemicalSubstance S-substituted dihydrolipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23750 GO:0044062 biolink:BiologicalProcess regulation of excretion Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. go-plus.json http://purl.obolibrary.org/obo/GO_0044062 GO:0044060 biolink:BiologicalProcess regulation of endocrine process Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. go-plus.json regulation of endocrine system process http://purl.obolibrary.org/obo/GO_0044060 CHEBI:47724 biolink:ChemicalSubstance vancomycin aglycone go-plus.json http://purl.obolibrary.org/obo/CHEBI_47724 GO:0044069 biolink:BiologicalProcess modulation by symbiont of host anion transport The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism. go-plus.json modification of host anion transport by symbiont http://purl.obolibrary.org/obo/GO_0044069 GO:0044067 biolink:BiologicalProcess modification by symbiont of host intercellular junctions The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells. go-plus.json modification of host intercellular junctions by symbiont http://purl.obolibrary.org/obo/GO_0044067 GO:0044068 biolink:BiologicalProcess modulation by symbiont of host cellular process Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism. go-plus.json modulation of host cellular process by symbiont|regulation by symbiont of host cellular process|regulation of host cellular process by symbiont http://purl.obolibrary.org/obo/GO_0044068 UBERON:0014387 biolink:AnatomicalEntity mesenchyme derived from neural crest Mesenchyme that develops_from the neural crest[Automatically generated definition]. go-plus.json neural crest derived mesenchyme|mesenchyme from neural crest|neural crest mesenchyme http://purl.obolibrary.org/obo/UBERON_0014387 UBERON:0014388 biolink:AnatomicalEntity kidney collecting duct epithelium The simple cuboidal epithelium lining the lumen of kidney collecting ducts. go-plus.json epithelium of collecting duct of renal tubule|collecting duct of renal tubule epithelium|epithelium of renal collecting tubule http://purl.obolibrary.org/obo/UBERON_0014388 GO:0044065 biolink:BiologicalProcess regulation of respiratory system process Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. go-plus.json http://purl.obolibrary.org/obo/GO_0044065 UBERON:0014389 biolink:AnatomicalEntity gustatory papilla of tongue A papilla that contain taste buds, including the fungiform, foliate, and circumvallate papillae. go-plus.json gustatory papillae|taste papillae|taste papilla|gustatory papilla http://purl.obolibrary.org/obo/UBERON_0014389 GO:0044066 biolink:BiologicalProcess modification by symbiont of host cell nucleus The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus. go-plus.json modification of host cell nucleus by symbiont|modification by symbiont of host nucleus|modification of host nucleus by symbiont http://purl.obolibrary.org/obo/GO_0044066 NCBITaxon:237561 biolink:OrganismalEntity Candida albicans SC5314 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_237561 GO:0044074 biolink:BiologicalProcess negative regulation by symbiont of host translation The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism. go-plus.json negative regulation of host translation by symbiont http://purl.obolibrary.org/obo/GO_0044074 UBERON:0014371 biolink:AnatomicalEntity future telencephalon Embryonic structure that gives rise to the telencephalon. go-plus.json presumptive telencephalon http://purl.obolibrary.org/obo/UBERON_0014371 GO:0044075 biolink:BiologicalProcess modulation by symbiont of host vacuole organization Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism. go-plus.json modulation of host vacuole organization by symbiont|regulation by symbiont of host vacuole organization|modulation by symbiont of host vacuole biogenesis|modulation by symbiont of host vacuole organisation http://purl.obolibrary.org/obo/GO_0044075 CHEBI:23763 biolink:ChemicalSubstance pyrroline go-plus.json http://purl.obolibrary.org/obo/CHEBI_23763 GO:0044072 biolink:BiologicalProcess negative regulation by symbiont of host cell cycle The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery. go-plus.json http://purl.obolibrary.org/obo/GO_0044072 GO:0044073 biolink:BiologicalProcess modulation by symbiont of host translation The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism. go-plus.json regulation by symbiont of host translation|modification by symbiont of host translation|modulation of host translation by symbiont http://purl.obolibrary.org/obo/GO_0044073 GO:0044070 biolink:BiologicalProcess regulation of anion transport Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0044070 GO:0044071 biolink:BiologicalProcess modulation by symbiont of host cell cycle The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery. go-plus.json regulation by symbiont of host cell cycle|modulation of host cell cycle by symbiont|modification by symbiont of host cell cycle http://purl.obolibrary.org/obo/GO_0044071 CHEBI:23765 biolink:ChemicalSubstance quinolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23765 GO:0044078 biolink:BiologicalProcess positive regulation by symbiont of host receptor-mediated endocytosis Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism. go-plus.json positive regulation of host receptor-mediated endocytosis by symbiont http://purl.obolibrary.org/obo/GO_0044078 GO:0044079 biolink:BiologicalProcess modulation by symbiont of host neurotransmitter secretion Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism. go-plus.json regulation by symbiont of host neurotransmitter secretion|modification by symbiont of host neurotransmitter secretion|modulation of host neurotransmitter secretion by symbiont http://purl.obolibrary.org/obo/GO_0044079 GO:0044076 biolink:BiologicalProcess positive regulation by symbiont of host vacuole organization The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism. go-plus.json positive regulation by symbiont of host vacuole biogenesis|positive regulation by symbiont of host vacuole organisation|positive regulation of host vacuole organization by symbiont http://purl.obolibrary.org/obo/GO_0044076 GO:0044077 biolink:BiologicalProcess modulation by symbiont of host receptor-mediated endocytosis The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism. go-plus.json regulation by symbiont of host receptor-mediated endocytosis|modulation of host receptor-mediated endocytosis by symbiont http://purl.obolibrary.org/obo/GO_0044077 GO:0093001 biolink:BiologicalProcess glycolysis from storage polysaccharide through glucose-1-phosphate The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH. go-plus.json http://purl.obolibrary.org/obo/GO_0093001 GO:0093002 biolink:BiologicalProcess response to nematicide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes. go-plus.json response to nematocide|response to antihelmintic http://purl.obolibrary.org/obo/GO_0093002 GO:0044085 biolink:BiologicalProcess cellular component biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. go-plus.json cellular component biogenesis at cellular level http://purl.obolibrary.org/obo/GO_0044085 goslim_pir GO:0044086 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044086 CHEBI:23730 biolink:ChemicalSubstance 5-oxo-2-furylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23730 GO:0044083 biolink:BiologicalProcess modulation by symbiont of host Rho protein signal transduction Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism. go-plus.json modulation of host Rho protein signaling by symbiont|modulation of host Rho protein signal transduction by symbiont|modulation by symbiont of host Rho protein mediated signal transduction|modulation of host Rho protein signalling by symbiont|regulation by symbiont of host Rho protein signal transduction|modulation by symbiont of host Rho protein-mediated signal transduction http://purl.obolibrary.org/obo/GO_0044083 GO:0044084 biolink:CellularComponent host cell membrane pore complex Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins. go-plus.json pore complex in host cell membrane http://purl.obolibrary.org/obo/GO_0044084 GO:0044081 biolink:BiologicalProcess modulation by symbiont of host nitric oxide-mediated signal transduction Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). go-plus.json modulation by symbiont of host nitric oxide mediated signal transduction|regulation by symbiont of host nitric oxide-mediated signal transduction|modulation of host nitric oxide-mediated signaling by symbiont|modulation of host nitric oxide-mediated signal transduction by symbiont|modulation of host nitric oxide-mediated signalling by symbiont http://purl.obolibrary.org/obo/GO_0044081 CHEBI:23733 biolink:ChemicalSubstance dihydrocarvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23733 chebi_ph7_3 GO:0044082 biolink:BiologicalProcess modulation by symbiont of host small GTPase mediated signal transduction Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism. go-plus.json regulation by symbiont of host small GTPase mediated signal transduction|modulation of host small GTPase mediated signal transduction by symbiont http://purl.obolibrary.org/obo/GO_0044082 GO:0044080 biolink:BiologicalProcess modulation by symbiont of host cGMP-mediated signal transduction Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. go-plus.json modulation by symbiont of host cGMP-mediated signal transduction pathway|modulation by symbiont of host cGMP-mediated signalling|modulation by symbiont of host cGMP-mediated signaling|modulation of host cGMP-mediated signal transduction by symbiont|regulation by symbiont of host cGMP-mediated signal transduction http://purl.obolibrary.org/obo/GO_0044080 GO:0044089 biolink:BiologicalProcess positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. go-plus.json http://purl.obolibrary.org/obo/GO_0044089 GO:0044087 biolink:BiologicalProcess regulation of cellular component biogenesis Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. go-plus.json http://purl.obolibrary.org/obo/GO_0044087 GO:0044088 biolink:BiologicalProcess regulation of vacuole organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. go-plus.json regulation of vacuole biogenesis|regulation of vacuole organisation http://purl.obolibrary.org/obo/GO_0044088 CHEBI:1387 biolink:ChemicalSubstance 3,4-dihydroxyphenylethyleneglycol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1387 chebi_ph7_3 CHEBI:23738 biolink:ChemicalSubstance dihydrophenanthrenediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23738 CHEBI:23736 biolink:ChemicalSubstance 4,5-dihydrocortisone go-plus.json http://purl.obolibrary.org/obo/CHEBI_23736 chebi_ph7_3 GO:0044096 biolink:CellularComponent type IV pilus A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers. go-plus.json type IV fimbriae|type 4 pilus|TFP http://purl.obolibrary.org/obo/GO_0044096 GO:0044097 biolink:BiologicalProcess secretion by the type IV secretion system The controlled release of proteins or DNA by a cell, via the type IV secretion system. go-plus.json secretion via the type IV secretion system http://purl.obolibrary.org/obo/GO_0044097 CHEBI:23741 biolink:ChemicalSubstance dihydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23741 GO:0044094 biolink:CellularComponent host cell nuclear part Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044094 gocheck_do_not_annotate GO:0044095 biolink:CellularComponent host cell nucleoplasm That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044095 GO:0044092 biolink:BiologicalProcess negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. go-plus.json http://purl.obolibrary.org/obo/GO_0044092 GO:0044093 biolink:BiologicalProcess positive regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. go-plus.json http://purl.obolibrary.org/obo/GO_0044093 GO:0044090 biolink:BiologicalProcess positive regulation of vacuole organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. go-plus.json positive regulation of vacuole biogenesis|positive regulation of vacuole organisation http://purl.obolibrary.org/obo/GO_0044090 GO:0044091 biolink:BiologicalProcess membrane biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044091 CHEBI:23743 biolink:ChemicalSubstance dihydrofolic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_23743 GO:0044098 biolink:BiologicalProcess DNA secretion by the type IV secretion system The controlled release of DNA by a cell, via the type IV secretion system. go-plus.json DNA secretion via the type IV secretion system http://purl.obolibrary.org/obo/GO_0044098 GO:0044099 biolink:CellularComponent polar tube A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044099 CHEBI:1395 biolink:ChemicalSubstance 3,5-dibromo-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1395 CHEBI:72687 biolink:ChemicalSubstance bacilysin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72687 GO:0010888 biolink:BiologicalProcess negative regulation of lipid storage Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. go-plus.json http://purl.obolibrary.org/obo/GO_0010888 GO:0034855 biolink:MolecularActivity 4-AD 9alpha-hydroxylase activity Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O. UM-BBD_reactionID:r1153|EC:1.14.15.- go-plus.json http://purl.obolibrary.org/obo/GO_0034855 GO:0010889 biolink:BiologicalProcess regulation of sequestering of triglyceride Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. go-plus.json regulation of sequestering of triacylglycerol|regulation of triacylglycerol sequestration http://purl.obolibrary.org/obo/GO_0010889 GO:0034856 biolink:MolecularActivity 2-hydroxyhexa-2,4-dienoate hydratase activity Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate. RHEA:32535|UM-BBD_reactionID:r1281|EC:4.2.1.132 go-plus.json http://purl.obolibrary.org/obo/GO_0034856 GO:0010886 biolink:BiologicalProcess positive regulation of cholesterol storage Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json positive regulation of cholesterol sequestration http://purl.obolibrary.org/obo/GO_0010886 GO:0034857 biolink:MolecularActivity 2-(methylthio)benzothiazole monooxygenase activity Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole. UM-BBD_reactionID:r1287 go-plus.json http://purl.obolibrary.org/obo/GO_0034857 GO:0010887 biolink:BiologicalProcess negative regulation of cholesterol storage Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json negative regulation of cholesterol sequestration http://purl.obolibrary.org/obo/GO_0010887 GO:0034858 biolink:MolecularActivity 2-hydroxybenzothiazole monooxygenase activity Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole. UM-BBD_reactionID:r1291 go-plus.json http://purl.obolibrary.org/obo/GO_0034858 GO:0034859 biolink:MolecularActivity benzothiazole monooxygenase activity Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole. UM-BBD_reactionID:r1292 go-plus.json http://purl.obolibrary.org/obo/GO_0034859 GO:0009891 biolink:BiologicalProcess positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. go-plus.json up regulation of biosynthetic process|positive regulation of anabolism|upregulation of biosynthetic process|positive regulation of synthesis|positive regulation of formation|stimulation of biosynthetic process|activation of biosynthetic process|up-regulation of biosynthetic process|positive regulation of biosynthesis http://purl.obolibrary.org/obo/GO_0009891 GO:0010880 biolink:BiologicalProcess regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels. go-plus.json http://purl.obolibrary.org/obo/GO_0010880 GO:0009892 biolink:BiologicalProcess negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. go-plus.json negative regulation of multicellular organismal metabolic process|inhibition of metabolic process|down regulation of metabolic process|inhibition of organismal metabolic process|negative regulation of organismal metabolism|downregulation of metabolic process|negative regulation of metabolism|down-regulation of metabolic process http://purl.obolibrary.org/obo/GO_0009892 GO:0010881 biolink:BiologicalProcess regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. go-plus.json http://purl.obolibrary.org/obo/GO_0010881 GO:0009893 biolink:BiologicalProcess positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. go-plus.json positive regulation of metabolism|up-regulation of metabolic process|positive regulation of multicellular organismal metabolic process|positive regulation of organismal metabolism|upregulation of metabolic process|up-regulation of organismal metabolic process|up regulation of metabolic process|activation of metabolic process|stimulation of organismal metabolic process|stimulation of metabolic process http://purl.obolibrary.org/obo/GO_0009893 GO:0009894 biolink:BiologicalProcess regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. go-plus.json regulation of catabolism|regulation of degradation|regulation of breakdown http://purl.obolibrary.org/obo/GO_0009894 GO:0034850 biolink:MolecularActivity isooctane monooxygenase activity Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol. EC:1.13.12.-|UM-BBD_reactionID:r1269 go-plus.json http://purl.obolibrary.org/obo/GO_0034850 GO:0009895 biolink:BiologicalProcess negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. go-plus.json negative regulation of breakdown|down-regulation of catabolic process|inhibition of catabolic process|negative regulation of catabolism|down regulation of catabolic process|negative regulation of degradation|downregulation of catabolic process http://purl.obolibrary.org/obo/GO_0009895 GO:0034851 biolink:MolecularActivity 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA. UM-BBD_reactionID:r1274 go-plus.json http://purl.obolibrary.org/obo/GO_0034851 GO:0010884 biolink:BiologicalProcess positive regulation of lipid storage Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. go-plus.json positive regulation of lipid sequestration http://purl.obolibrary.org/obo/GO_0010884 GO:0019218 biolink:BiologicalProcess regulation of steroid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. go-plus.json regulation of steroid metabolism http://purl.obolibrary.org/obo/GO_0019218 GO:0009896 biolink:BiologicalProcess positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. go-plus.json up regulation of catabolic process|activation of catabolic process|stimulation of catabolic process|up-regulation of catabolic process|upregulation of catabolic process|positive regulation of degradation|positive regulation of catabolism|positive regulation of breakdown http://purl.obolibrary.org/obo/GO_0009896 GO:0019219 biolink:BiologicalProcess regulation of nucleobase-containing compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. go-plus.json regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0019219 GO:0034852 biolink:MolecularActivity 4,4-dimethyl-3-oxopentanal dehydrogenase activity Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-. UM-BBD_reactionID:r1309 go-plus.json http://purl.obolibrary.org/obo/GO_0034852 GO:0010885 biolink:BiologicalProcess regulation of cholesterol storage Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json http://purl.obolibrary.org/obo/GO_0010885 GO:0009897 biolink:CellularComponent external side of plasma membrane The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. go-plus.json juxtamembrane|outer surface of cytoplasmic membrane|external leaflet of plasma membrane http://purl.obolibrary.org/obo/GO_0009897 GO:0034853 biolink:MolecularActivity 2,4,4-trimethyl-3-oxopentanoate decarboxylase activity Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2. UM-BBD_reactionID:r1278 go-plus.json http://purl.obolibrary.org/obo/GO_0034853 GO:0019216 biolink:BiologicalProcess regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. go-plus.json regulation of lipid metabolism http://purl.obolibrary.org/obo/GO_0019216 GO:0010882 biolink:BiologicalProcess regulation of cardiac muscle contraction by calcium ion signaling Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction. go-plus.json regulation of cardiac muscle contraction by calcium ion signalling http://purl.obolibrary.org/obo/GO_0010882 GO:0009898 biolink:CellularComponent cytoplasmic side of plasma membrane The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface. go-plus.json juxtamembrane|internal leaflet of plasma membrane|internal side of plasma membrane http://purl.obolibrary.org/obo/GO_0009898 GO:0010883 biolink:BiologicalProcess regulation of lipid storage Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. go-plus.json regulation of lipid sequestration http://purl.obolibrary.org/obo/GO_0010883 GO:0019217 biolink:BiologicalProcess regulation of fatty acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. go-plus.json regulation of fatty acid metabolism http://purl.obolibrary.org/obo/GO_0019217 GO:0034854 biolink:MolecularActivity 4,4-dimethyl-3-oxopentanoate decarboxylase activity Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2. UM-BBD_reactionID:r1280 go-plus.json http://purl.obolibrary.org/obo/GO_0034854 GO:0009899 biolink:MolecularActivity ent-kaurene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate. MetaCyc:4.2.3.19-RXN|KEGG_REACTION:R05092|EC:4.2.3.19|RHEA:22220 go-plus.json ent-kaurene synthase B activity|ent-copalyl-diphosphate diphosphate-lyase (cyclizing)|ent-kaurene synthetase B activity|ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming) http://purl.obolibrary.org/obo/GO_0009899 GO:0019214 biolink:MolecularActivity obsolete surfactant activity OBSOLETE. The action of reducing the surface tension of a liquid. go-plus.json surfactant activity http://purl.obolibrary.org/obo/GO_0019214 PO:0008016 biolink:OntologyClass vegetative shoot apical meristem A shoot apical meristem (PO:0020148) that gives rise to the apical growth of vegetative tissues and organs. go-plus.json meristema vegetativo apical del epiblasto (epiblastema) (Spanish, exact)|vegetative meristem (related)|栄養シュート頂端分裂組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0008016 CHEBI:33070 biolink:ChemicalSubstance indole-3-butyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33070 GO:0019215 biolink:MolecularActivity intermediate filament binding Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. go-plus.json http://purl.obolibrary.org/obo/GO_0019215 GO:0019212 biolink:MolecularActivity phosphatase inhibitor activity Binds to and stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019212 GO:0019213 biolink:MolecularActivity deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. Reactome:R-HSA-5689000 go-plus.json http://purl.obolibrary.org/obo/GO_0019213 goslim_pir CHEBI:72681 biolink:ChemicalSubstance (3S)-versiconol acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72681 GO:0019210 biolink:MolecularActivity kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0019210 CHEBI:72682 biolink:ChemicalSubstance 1-lauroyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72682 chebi_ph7_3 GO:0019211 biolink:MolecularActivity phosphatase activator activity Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019211 CHEBI:72683 biolink:ChemicalSubstance 1-myristoyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72683 chebi_ph7_3 CHEBI:33076 biolink:ChemicalSubstance D-mannonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33076 CHEBI:72696 biolink:ChemicalSubstance cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72696 CHEBI:72697 biolink:ChemicalSubstance (2R)-dihomocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72697 chebi_ph7_3 CHEBI:72698 biolink:ChemicalSubstance (2R)-trihomocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72698 CHEBI:72699 biolink:ChemicalSubstance (2R)-trihomocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72699 chebi_ph7_3 GO:0010899 biolink:BiologicalProcess regulation of phosphatidylcholine catabolic process Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. go-plus.json http://purl.obolibrary.org/obo/GO_0010899 GO:0034844 biolink:MolecularActivity naphthyl-2-methyl-succinate CoA-transferase activity Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate. UM-BBD_reactionID:r1256 go-plus.json http://purl.obolibrary.org/obo/GO_0034844 GO:0034845 biolink:MolecularActivity naphthyl-2-methyl-succinyl-CoA dehydrogenase activity Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-. EC:1.3.99.-|UM-BBD_reactionID:r1258 go-plus.json http://purl.obolibrary.org/obo/GO_0034845 GO:0010897 biolink:BiologicalProcess negative regulation of triglyceride catabolic process Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. go-plus.json negative regulation of triacylglycerol catabolic process http://purl.obolibrary.org/obo/GO_0010897 GO:0034846 biolink:MolecularActivity naphthyl-2-methylene-succinyl-CoA lyase activity Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA. UM-BBD_reactionID:r1259 go-plus.json http://purl.obolibrary.org/obo/GO_0034846 GO:0010898 biolink:BiologicalProcess positive regulation of triglyceride catabolic process Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. go-plus.json positive regulation of triacylglycerol catabolic process http://purl.obolibrary.org/obo/GO_0010898 GO:0034847 biolink:MolecularActivity naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r1260 go-plus.json http://purl.obolibrary.org/obo/GO_0034847 GO:0034848 biolink:MolecularActivity naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA. UM-BBD_reactionID:r1261 go-plus.json http://purl.obolibrary.org/obo/GO_0034848 GO:0034849 biolink:MolecularActivity 2-naphthoate CoA-transferase activity Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH. UM-BBD_reactionID:r1262 go-plus.json http://purl.obolibrary.org/obo/GO_0034849 GO:0010891 biolink:BiologicalProcess negative regulation of sequestering of triglyceride Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. go-plus.json negative regulation of sequestering of triacylglycerol|negative regulation of triglyceride sequestration http://purl.obolibrary.org/obo/GO_0010891 GO:0010892 biolink:BiologicalProcess positive regulation of mitochondrial translation in response to stress Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress. go-plus.json http://purl.obolibrary.org/obo/GO_0010892 GO:0010890 biolink:BiologicalProcess positive regulation of sequestering of triglyceride Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. go-plus.json positive regulation of triglyceride sequestration|positive regulation of sequestering of triacylglycerol http://purl.obolibrary.org/obo/GO_0010890 GO:0019229 biolink:BiologicalProcess regulation of vasoconstriction Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0019229 GO:0010895 biolink:BiologicalProcess negative regulation of ergosterol biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol. go-plus.json http://purl.obolibrary.org/obo/GO_0010895 GO:0034840 biolink:MolecularActivity 3-hydroxymenthone dehydrogenase activity Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+. UM-BBD_reactionID:r1185 go-plus.json http://purl.obolibrary.org/obo/GO_0034840 GO:0034841 biolink:MolecularActivity mentha-1,3-dione-CoA ligase activity Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA. UM-BBD_reactionID:r1186 go-plus.json http://purl.obolibrary.org/obo/GO_0034841 GO:0010896 biolink:BiologicalProcess regulation of triglyceride catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. go-plus.json regulation of triacylglycerol catabolic process http://purl.obolibrary.org/obo/GO_0010896 GO:0034842 biolink:MolecularActivity thiophene-2-carboxylate-CoA ligase activity Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi. UM-BBD_reactionID:r1234 go-plus.json http://purl.obolibrary.org/obo/GO_0034842 GO:0010893 biolink:BiologicalProcess positive regulation of steroid biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0010893 GO:0019227 biolink:BiologicalProcess neuronal action potential propagation The propagation of an action potential along an axon, away from the soma. go-plus.json http://purl.obolibrary.org/obo/GO_0019227 GO:0010894 biolink:BiologicalProcess negative regulation of steroid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0010894 GO:0034843 biolink:MolecularActivity 2-oxoglutaryl-CoA thioesterase activity Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH. UM-BBD_reactionID:r1238 go-plus.json http://purl.obolibrary.org/obo/GO_0034843 GO:0019228 biolink:BiologicalProcess neuronal action potential An action potential that occurs in a neuron. go-plus.json generation of action potential http://purl.obolibrary.org/obo/GO_0019228 GO:0019225 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019225 GO:0019226 biolink:BiologicalProcess transmission of nerve impulse The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. go-plus.json conduction of nerve impulse|signal transmission along a neuron http://purl.obolibrary.org/obo/GO_0019226 GO:0019223 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019223 CHEBI:33082 biolink:ChemicalSubstance phenalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_33082 chebi_ph7_3 GO:0019224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019224 GO:0019221 biolink:BiologicalProcess cytokine-mediated signaling pathway A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json cytokine and chemokine mediated signaling pathway|cytokine mediated signalling pathway http://purl.obolibrary.org/obo/GO_0019221 CHEBI:72692 biolink:ChemicalSubstance polyunsaturated fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_72692 GO:0019222 biolink:BiologicalProcess regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. go-plus.json regulation of organismal metabolic process|regulation of metabolism|regulation of multicellular organismal metabolic process http://purl.obolibrary.org/obo/GO_0019222 goslim_metagenomics CHEBI:72694 biolink:ChemicalSubstance (2R)-dihomocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72694 GO:0019220 biolink:BiologicalProcess regulation of phosphate metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. go-plus.json regulation of phosphate metabolism http://purl.obolibrary.org/obo/GO_0019220 CHEBI:72695 biolink:ChemicalSubstance organic molecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_72695 GO:0010866 biolink:BiologicalProcess regulation of triglyceride biosynthetic process Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. go-plus.json regulation of triacylglycerol biosynthetic process http://purl.obolibrary.org/obo/GO_0010866 GO:0044203 biolink:CellularComponent host cell nuclear lamina The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0044203 GO:0034833 biolink:MolecularActivity geranylate CoA-transferase activity Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-. UM-BBD_reactionID:r1165 go-plus.json http://purl.obolibrary.org/obo/GO_0034833 GO:0044204 biolink:CellularComponent host cell nuclear matrix The dense fibrillar network lying on the inner side of the host nuclear membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044204 GO:0034834 biolink:MolecularActivity 2-mercaptobenzothiazole dioxygenase activity Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol. EC:1.13.11.-|UM-BBD_reactionID:r1177 go-plus.json http://purl.obolibrary.org/obo/GO_0034834 GO:0010867 biolink:BiologicalProcess positive regulation of triglyceride biosynthetic process Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. go-plus.json positive regulation of triacylglycerol biosynthetic process http://purl.obolibrary.org/obo/GO_0010867 GO:0034835 biolink:MolecularActivity 2-mercaptobenzothiazole monooxygenase activity Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole. EC:1.13.12.-|UM-BBD_reactionID:r1178 go-plus.json http://purl.obolibrary.org/obo/GO_0034835 GO:0010864 biolink:BiologicalProcess positive regulation of protein histidine kinase activity Any process that increases the frequency, rate or extent of protein histidine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0010864 GO:0044201 biolink:CellularComponent host cell nuclear inner membrane The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0044201 GO:0034836 biolink:MolecularActivity 6-hydroxy-2-mercaptobenzothiazole monooxygenase activity Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole. EC:1.13.12.-|UM-BBD_reactionID:r1181 go-plus.json http://purl.obolibrary.org/obo/GO_0034836 GO:0044202 biolink:CellularComponent host cell nuclear outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0044202 GO:0010865 biolink:BiologicalProcess stipule development The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms. go-plus.json http://purl.obolibrary.org/obo/GO_0010865 NCBITaxon:404260 biolink:OrganismalEntity Bryophytina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_404260 GO:0034837 biolink:MolecularActivity 2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-. UM-BBD_reactionID:r1179 go-plus.json http://purl.obolibrary.org/obo/GO_0034837 GO:0034838 biolink:MolecularActivity menthone dehydrogenase activity Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+. UM-BBD_reactionID:r1183 go-plus.json http://purl.obolibrary.org/obo/GO_0034838 GO:0044200 biolink:CellularComponent host cell nuclear membrane Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0044200 GO:0010868 biolink:BiologicalProcess negative regulation of triglyceride biosynthetic process Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. go-plus.json negative regulation of triacylglycerol biosynthetic process http://purl.obolibrary.org/obo/GO_0010868 GO:0034839 biolink:MolecularActivity menth-2-enone hydratase activity Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone. UM-BBD_reactionID:r1184 go-plus.json http://purl.obolibrary.org/obo/GO_0034839 GO:0010869 biolink:BiologicalProcess obsolete regulation of receptor biosynthetic process OBSOLETE. Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json http://purl.obolibrary.org/obo/GO_0010869 GO:0009870 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009870 CHEBI:1189 biolink:ChemicalSubstance 2-methoxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_1189 chebi_ph7_3 GO:0044209 biolink:BiologicalProcess AMP salvage The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis. go-plus.json AMP biosynthetic process via salvage pathway|adenosine monophosphate salvage http://purl.obolibrary.org/obo/GO_0044209 GO:0009871 biolink:BiologicalProcess jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance. go-plus.json jasmonic acid and ethene-dependent systemic resistance, ethene mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signalling pathway|ethene mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)|ethylene mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signalling pathway http://purl.obolibrary.org/obo/GO_0009871 GO:0009872 biolink:BiologicalProcess obsolete gametophytic self-incompatibility OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place. go-plus.json gametophytic self-incompatibility http://purl.obolibrary.org/obo/GO_0009872 GO:0009873 biolink:BiologicalProcess ethylene-activated signaling pathway A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription. go-plus.json ethylene mediated signalling pathway|ethylene mediated signaling pathway|ethene mediated signalling pathway|ethylene signaling pathway|ethene mediated signaling pathway|ethylene signal transduction http://purl.obolibrary.org/obo/GO_0009873 GO:0010862 biolink:BiologicalProcess positive regulation of pathway-restricted SMAD protein phosphorylation Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0010862 GO:0044207 biolink:CellularComponent translation initiation ternary complex A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). go-plus.json Met-tRNA/eIF2.GTP ternary complex|translation initiation (ternary) complex http://purl.obolibrary.org/obo/GO_0044207 GO:0044208 biolink:BiologicalProcess 'de novo' AMP biosynthetic process The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP). go-plus.json http://purl.obolibrary.org/obo/GO_0044208 GO:0034830 biolink:MolecularActivity (2Z)-2,4-dihydroxydec-2-enedioate aldolase activity Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate. UM-BBD_reactionID:r1174|EC:4.1.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0034830 GO:0010863 biolink:BiologicalProcess positive regulation of phospholipase C activity Any process that increases the rate of phospholipase C activity. go-plus.json http://purl.obolibrary.org/obo/GO_0010863 GO:0009874 biolink:BiologicalProcess obsolete sporophytic self-incompatibility OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place. go-plus.json sporophytic self-incompatibility http://purl.obolibrary.org/obo/GO_0009874 GO:0044205 biolink:BiologicalProcess 'de novo' UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen. go-plus.json 'de novo' UMP biosynthesis http://purl.obolibrary.org/obo/GO_0044205 GO:0034831 biolink:MolecularActivity (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-. UM-BBD_reactionID:r1176 go-plus.json http://purl.obolibrary.org/obo/GO_0034831 GO:0010860 biolink:MolecularActivity obsolete proteasome regulator activity OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis. go-plus.json proteasome regulator activity http://purl.obolibrary.org/obo/GO_0010860 GO:0009875 biolink:BiologicalProcess pollen-pistil interaction The interaction between a pollen grain and pistil. go-plus.json pollen-gynoecium interaction http://purl.obolibrary.org/obo/GO_0009875 GO:0044206 biolink:BiologicalProcess UMP salvage Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis. go-plus.json UMP biosynthesis via nucleoside salvage pathway|UMP biosynthetic process via nucleoside salvage pathway http://purl.obolibrary.org/obo/GO_0044206 GO:0034832 biolink:MolecularActivity geranial dehydrogenase activity Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+. UM-BBD_reactionID:r1164 go-plus.json http://purl.obolibrary.org/obo/GO_0034832 GO:0010861 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010861 GO:0009876 biolink:BiologicalProcess pollen adhesion The process in which pollen deposited on the stigma adheres to cells of the stigma. go-plus.json http://purl.obolibrary.org/obo/GO_0009876 GO:0009877 biolink:BiologicalProcess nodulation The formation of nitrogen-fixing root nodules on plant roots. go-plus.json nodule morphogenesis|nodule development|nodule formation http://purl.obolibrary.org/obo/GO_0009877 GO:0009878 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009878 GO:0009879 biolink:BiologicalProcess determination of radial symmetry The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis. go-plus.json determination of radial asymmetry http://purl.obolibrary.org/obo/GO_0009879 CHEBI:1184 biolink:ChemicalSubstance maleylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1184 GO:0034822 biolink:MolecularActivity citronellal dehydrogenase activity Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+. UM-BBD_reactionID:r1156 go-plus.json http://purl.obolibrary.org/obo/GO_0034822 GO:0010877 biolink:BiologicalProcess lipid transport involved in lipid storage The directed movement of lipids into cells that is part of their accumulation and maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_0010877 GO:0044214 biolink:CellularComponent spanning component of plasma membrane The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane. go-plus.json transmembrane|fully spanning plasma membrane http://purl.obolibrary.org/obo/GO_0044214 GO:0034823 biolink:MolecularActivity citronellyl-CoA ligase activity Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi. KEGG_REACTION:R08088|UM-BBD_reactionID:r1157 go-plus.json http://purl.obolibrary.org/obo/GO_0034823 GO:0010878 biolink:BiologicalProcess cholesterol storage The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. go-plus.json cholesterol sequestration|sequestration of cholesterol http://purl.obolibrary.org/obo/GO_0010878 GO:0044215 biolink:CellularComponent obsolete other organism OBSOLETE. A secondary organism with which the first organism is interacting. go-plus.json http://purl.obolibrary.org/obo/GO_0044215 GO:0034824 biolink:MolecularActivity citronellyl-CoA dehydrogenase activity Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+. UM-BBD_reactionID:r1159 go-plus.json http://purl.obolibrary.org/obo/GO_0034824 GO:0010875 biolink:BiologicalProcess positive regulation of cholesterol efflux Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0010875 GO:0044212 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044212 GO:0034825 biolink:MolecularActivity tetralin ring-hydroxylating dioxygenase activity Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+. EC:1.14.12.-|UM-BBD_reactionID:r1169 go-plus.json http://purl.obolibrary.org/obo/GO_0034825 GO:0010876 biolink:BiologicalProcess lipid localization Any process in which a lipid is transported to, or maintained in, a specific location. go-plus.json lipid localisation http://purl.obolibrary.org/obo/GO_0010876 GO:0044213 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044213 GO:0034826 biolink:MolecularActivity 1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+. UM-BBD_reactionID:r1170 go-plus.json http://purl.obolibrary.org/obo/GO_0034826 GO:0044210 biolink:BiologicalProcess 'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components. go-plus.json 'de novo' cytidine 5'-triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0044210 GO:0044211 biolink:BiologicalProcess CTP salvage Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis. go-plus.json cytidine 5'-triphosphate salvage|CTP biosynthetic process via salvage pathway http://purl.obolibrary.org/obo/GO_0044211 GO:0034827 biolink:MolecularActivity 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+. UM-BBD_reactionID:r1171|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034827 CHEBI:47693 biolink:ChemicalSubstance keto-D-tagatose go-plus.json http://purl.obolibrary.org/obo/CHEBI_47693 chebi_ph7_3 GO:0034828 biolink:MolecularActivity 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+. UM-BBD_reactionID:r1172 go-plus.json http://purl.obolibrary.org/obo/GO_0034828 GO:0010879 biolink:BiologicalProcess cholesterol transport involved in cholesterol storage The directed movement of cholesterol into cells that is part of their accumulation and maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_0010879 GO:0009890 biolink:BiologicalProcess negative regulation of biosynthetic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. go-plus.json downregulation of biosynthetic process|down regulation of biosynthetic process|inhibition of biosynthetic process|negative regulation of anabolism|negative regulation of synthesis|negative regulation of formation|down-regulation of biosynthetic process|negative regulation of biosynthesis http://purl.obolibrary.org/obo/GO_0009890 GO:0034829 biolink:MolecularActivity 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate. UM-BBD_reactionID:r1172 go-plus.json http://purl.obolibrary.org/obo/GO_0034829 GO:0009880 biolink:BiologicalProcess embryonic pattern specification The process that results in the patterns of cell differentiation that will arise in an embryo. go-plus.json embryonic pattern formation|ventral/lateral system|embryonic pattern biosynthesis http://purl.obolibrary.org/obo/GO_0009880 GO:0010870 biolink:BiologicalProcess obsolete positive regulation of receptor biosynthetic process OBSOLETE. Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json http://purl.obolibrary.org/obo/GO_0010870 GO:0009881 biolink:MolecularActivity photoreceptor activity The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation. go-plus.json short-wave-sensitive opsin|long-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|violet-sensitive opsin|blue-sensitive opsin|opsin|red-sensitive opsin http://purl.obolibrary.org/obo/GO_0009881 GO:0019209 biolink:MolecularActivity kinase activator activity Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019209 GO:0009882 biolink:MolecularActivity blue light photoreceptor activity The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation. go-plus.json http://purl.obolibrary.org/obo/GO_0009882 GO:0009883 biolink:MolecularActivity red or far-red light photoreceptor activity The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation. go-plus.json red/far-red light photoreceptor activity http://purl.obolibrary.org/obo/GO_0009883 GO:0010873 biolink:BiologicalProcess positive regulation of cholesterol esterification Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0010873 GO:0009884 biolink:MolecularActivity cytokinin receptor activity Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0009884 GO:0019207 biolink:MolecularActivity kinase regulator activity Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019207 GO:0044218 biolink:CellularComponent other organism cell membrane The cell membrane of a secondary organism with which the first organism is interacting. go-plus.json foreign membrane|other organism membrane http://purl.obolibrary.org/obo/GO_0044218 GO:0010874 biolink:BiologicalProcess regulation of cholesterol efflux Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0010874 GO:0019208 biolink:MolecularActivity phosphatase regulator activity Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0019208 GO:0044219 biolink:CellularComponent host cell plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044219 GO:0009885 biolink:MolecularActivity transmembrane histidine kinase cytokinin receptor activity Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0009885 GO:0010871 biolink:BiologicalProcess obsolete negative regulation of receptor biosynthetic process OBSOLETE. Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json http://purl.obolibrary.org/obo/GO_0010871 GO:0034820 biolink:MolecularActivity 4,9-DSHA hydrolase activity Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+. UM-BBD_reactionID:r1152 go-plus.json http://purl.obolibrary.org/obo/GO_0034820 GO:0019205 biolink:MolecularActivity nucleobase-containing compound kinase activity Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate. go-plus.json nucleobase, nucleoside, nucleotide kinase activity http://purl.obolibrary.org/obo/GO_0019205 GO:0009886 biolink:BiologicalProcess post-embryonic animal morphogenesis The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. go-plus.json post-embryonic morphogenesis of an anatomical structure http://purl.obolibrary.org/obo/GO_0009886 GO:0044216 biolink:CellularComponent obsolete other organism cell OBSOLETE. A cell of a secondary organism with which the first organism is interacting. go-plus.json http://purl.obolibrary.org/obo/GO_0044216 GO:0034821 biolink:MolecularActivity citronellol dehydrogenase activity Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+. UM-BBD_reactionID:r1155 go-plus.json http://purl.obolibrary.org/obo/GO_0034821 GO:0010872 biolink:BiologicalProcess regulation of cholesterol esterification Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. go-plus.json http://purl.obolibrary.org/obo/GO_0010872 GO:0019206 biolink:MolecularActivity nucleoside kinase activity Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate. Reactome:R-HSA-110138|Reactome:R-HSA-109903|Reactome:R-HSA-73632|Reactome:R-HSA-110137|Reactome:R-HSA-74207|Reactome:R-HSA-73598|Reactome:R-HSA-109671|Reactome:R-HSA-73599|Reactome:R-HSA-109759 go-plus.json http://purl.obolibrary.org/obo/GO_0019206 GO:0009887 biolink:BiologicalProcess animal organ morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json histogenesis and organogenesis http://purl.obolibrary.org/obo/GO_0009887 GO:0044217 biolink:CellularComponent other organism part Any constituent part of a secondary organism with which the first organism is interacting. go-plus.json http://purl.obolibrary.org/obo/GO_0044217 gocheck_do_not_annotate GO:0009888 biolink:BiologicalProcess tissue development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. Wikipedia:Histogenesis go-plus.json histogenesis and organogenesis|histogenesis http://purl.obolibrary.org/obo/GO_0009888 GO:0019203 biolink:MolecularActivity carbohydrate phosphatase activity Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate. Reactome:R-HSA-3781011|Reactome:R-HSA-3791349|Reactome:R-HSA-3781018 go-plus.json http://purl.obolibrary.org/obo/GO_0019203 GO:0019204 biolink:MolecularActivity obsolete nucleotide phosphatase activity OBSOLETE. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate. go-plus.json nucleotide phosphatase activity http://purl.obolibrary.org/obo/GO_0019204 GO:0009889 biolink:BiologicalProcess regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. go-plus.json regulation of anabolism|regulation of synthesis|regulation of biosynthesis|regulation of formation http://purl.obolibrary.org/obo/GO_0009889 GO:0019201 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019201 GO:0019202 biolink:MolecularActivity amino acid kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0019202 GO:0019200 biolink:MolecularActivity carbohydrate kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule. Reactome:R-HSA-8931653 go-plus.json http://purl.obolibrary.org/obo/GO_0019200 GO:0034819 biolink:MolecularActivity 3-HSA hydroxylase activity Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O. EC:1.14.13.-|UM-BBD_reactionID:r1150 go-plus.json http://purl.obolibrary.org/obo/GO_0034819 GO:0010844 biolink:MolecularActivity recombination hotspot binding Binding to a genomic region which promotes recombination. go-plus.json DNA binding, recombination hotspot http://purl.obolibrary.org/obo/GO_0010844 GO:0034811 biolink:MolecularActivity benzo(a)pyrene 9,10-dioxygenase activity Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol. EC:1.13.11.-|UM-BBD_reactionID:r1132 go-plus.json http://purl.obolibrary.org/obo/GO_0034811 GO:0044225 biolink:CellularComponent apical pole of neuron Portion of a neuron cell soma closest to the point where the apical dendrite emerges. NIF_Subcellular:sao1186862860 go-plus.json http://purl.obolibrary.org/obo/GO_0044225 GO:0010845 biolink:BiologicalProcess positive regulation of reciprocal meiotic recombination Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json positive regulation of meiotic recombination http://purl.obolibrary.org/obo/GO_0010845 GO:0034812 biolink:MolecularActivity 9,10-dihydroxybenzo(a)pyrene dioxygenase activity Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate. EC:1.13.11.-|UM-BBD_reactionID:r1134 go-plus.json http://purl.obolibrary.org/obo/GO_0034812 GO:0044226 biolink:CellularComponent basal pole of neuron Portion of a neuron cell soma closest to the point where the basilar dendrite emerges. NIF_Subcellular:sao1186862860 go-plus.json http://purl.obolibrary.org/obo/GO_0044226 GO:0044223 biolink:CellularComponent pirellulosome A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0044223 GO:0034813 biolink:MolecularActivity benzo(a)pyrene 7,8-dioxygenase activity Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol. EC:1.13.11.-|UM-BBD_reactionID:r1137 go-plus.json http://purl.obolibrary.org/obo/GO_0034813 GO:0010842 biolink:BiologicalProcess retina layer formation The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. go-plus.json retinal layer formation|retinal lamination http://purl.obolibrary.org/obo/GO_0010842 GO:0010843 biolink:MolecularActivity obsolete promoter binding OBSOLETE. Binding to a regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery. go-plus.json DNA binding, transcription promoter|promoter binding http://purl.obolibrary.org/obo/GO_0010843 GO:0044224 biolink:CellularComponent juxtaparanode region of axon A region of an axon near a node of Ranvier that is between the paranode and internode regions. NIF_Subcellular:sao758620702 go-plus.json juxtaparanodal region|juxtaparanode|juxta paranode axon http://purl.obolibrary.org/obo/GO_0044224 GO:0034814 biolink:MolecularActivity 7,8-dihydroxy benzo(a)pyrene dioxygenase activity Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate. EC:1.13.11.-|UM-BBD_reactionID:r1138 go-plus.json http://purl.obolibrary.org/obo/GO_0034814 GO:0044221 biolink:CellularComponent host cell synapse The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication. go-plus.json http://purl.obolibrary.org/obo/GO_0044221 GO:0034815 biolink:MolecularActivity cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+. UM-BBD_reactionID:r1135|EC:4.1.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0034815 GO:0010848 biolink:BiologicalProcess regulation of chromatin disassembly Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010848 GO:0044222 biolink:CellularComponent anammoxosome An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044222 GO:0010849 biolink:BiologicalProcess regulation of proton-transporting ATPase activity, rotational mechanism Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism. go-plus.json regulation of V-type ATPase activity|regulation of hydrogen ion transporting ATPase activity, rotational mechanism http://purl.obolibrary.org/obo/GO_0010849 GO:0034816 biolink:MolecularActivity anthracene 9,10-dioxygenase activity Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol. UM-BBD_reactionID:r1141 go-plus.json http://purl.obolibrary.org/obo/GO_0034816 GO:0034817 biolink:MolecularActivity cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-. UM-BBD_reactionID:r1144 go-plus.json http://purl.obolibrary.org/obo/GO_0034817 GO:0010846 biolink:BiologicalProcess activation of reciprocal meiotic recombination Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. go-plus.json activation of meiotic recombination http://purl.obolibrary.org/obo/GO_0010846 GO:0044220 biolink:CellularComponent host cell perinuclear region of cytoplasm The host cell cytoplasm situated near, or occurring around, the host nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0044220 GO:0034818 biolink:MolecularActivity ADD 9alpha-hydroxylase activity Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin. EC:1.14.15.-|UM-BBD_reactionID:r1149 go-plus.json http://purl.obolibrary.org/obo/GO_0034818 GO:0010847 biolink:BiologicalProcess regulation of chromatin assembly Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0010847 CHEBI:33033 biolink:ChemicalSubstance 2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33033 GO:0009850 biolink:BiologicalProcess auxin metabolic process The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth. go-plus.json auxin metabolism http://purl.obolibrary.org/obo/GO_0009850 GO:0044229 biolink:CellularComponent host cell periplasmic space The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi). go-plus.json http://purl.obolibrary.org/obo/GO_0044229 GO:0010840 biolink:BiologicalProcess regulation of circadian sleep/wake cycle, wakefulness Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep. go-plus.json http://purl.obolibrary.org/obo/GO_0010840 GO:0009851 biolink:BiologicalProcess auxin biosynthetic process The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. go-plus.json auxin biosynthesis|auxin anabolism|auxin synthesis|auxin formation http://purl.obolibrary.org/obo/GO_0009851 GO:0009852 biolink:BiologicalProcess auxin catabolic process The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth. go-plus.json auxin breakdown|auxin catabolism|auxin degradation http://purl.obolibrary.org/obo/GO_0009852 GO:0010841 biolink:BiologicalProcess positive regulation of circadian sleep/wake cycle, wakefulness Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep. go-plus.json http://purl.obolibrary.org/obo/GO_0010841 GO:0009853 biolink:BiologicalProcess photorespiration A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria. MetaCyc:PWY-181|Wikipedia:Photorespiration go-plus.json http://purl.obolibrary.org/obo/GO_0009853 GO:0044227 biolink:CellularComponent methane-oxidizing organelle A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms. go-plus.json methanotroph intracytoplasmic membrane-bound compartment|methane-oxidizing compartment http://purl.obolibrary.org/obo/GO_0044227 GO:0034810 biolink:MolecularActivity 4,5-dihydroxybenzo(a)pyrene dioxygenase activity Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate. EC:1.13.11.-|UM-BBD_reactionID:r1128 go-plus.json http://purl.obolibrary.org/obo/GO_0034810 GO:0044228 biolink:CellularComponent host cell surface The external part of the host cell wall and/or host plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0044228 GO:0009854 biolink:BiologicalProcess oxidative photosynthetic carbon pathway The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2). go-plus.json http://purl.obolibrary.org/obo/GO_0009854 GO:0009855 biolink:BiologicalProcess determination of bilateral symmetry The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. go-plus.json determination of bilateral asymmetry http://purl.obolibrary.org/obo/GO_0009855 GO:0009856 biolink:BiologicalProcess pollination The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion. Wikipedia:Pollination go-plus.json http://purl.obolibrary.org/obo/GO_0009856 goslim_plant GO:0009857 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009857 GO:0009858 biolink:BiologicalProcess obsolete compatible pollen-pistil interaction OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style. go-plus.json compatible pollen-pistil interaction http://purl.obolibrary.org/obo/GO_0009858 GO:0009859 biolink:BiologicalProcess pollen hydration The process in which water is taken up by pollen. go-plus.json http://purl.obolibrary.org/obo/GO_0009859 GO:0034808 biolink:MolecularActivity benzo(a)pyrene 4,5-dioxygenase activity Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol. EC:1.13.11.-|UM-BBD_reactionID:r1126 go-plus.json http://purl.obolibrary.org/obo/GO_0034808 GO:0034809 biolink:MolecularActivity benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2. UM-BBD_reactionID:r1127 go-plus.json http://purl.obolibrary.org/obo/GO_0034809 GO:0034800 biolink:MolecularActivity trinitrophenol dihydride denitratase activity Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP. EC:1.7.99.-|UM-BBD_reactionID:r1067 go-plus.json 2,4,6-trinitrophenol dihydride denitratase activity|TNP dihydride denitratase activity http://purl.obolibrary.org/obo/GO_0034800 GO:0010855 biolink:MolecularActivity adenylate cyclase inhibitor activity Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010855 GO:0044236 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044236 GO:0034801 biolink:MolecularActivity 2,4-dinitrocyclohexanone hydrolase activity Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate. UM-BBD_reactionID:r1069 go-plus.json http://purl.obolibrary.org/obo/GO_0034801 GO:0044237 biolink:BiologicalProcess cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances. go-plus.json intermediary metabolism|cellular metabolism http://purl.obolibrary.org/obo/GO_0044237 GO:0010856 biolink:MolecularActivity adenylate cyclase activator activity Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010856 GO:0034802 biolink:MolecularActivity branched-chain dodecylbenzene sulfonate monooxygenase activity Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite. EC:1.14.13.-|UM-BBD_reactionID:r1079 go-plus.json http://purl.obolibrary.org/obo/GO_0034802 GO:0010853 biolink:MolecularActivity cyclase activator activity Increases the activity of an enzyme that catalyzes a ring closure reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0010853 GO:0044234 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044234 GO:0034803 biolink:MolecularActivity 3-hydroxy-2-naphthoate 2,3-dioxygenase activity Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate. EC:1.13.11.-|UM-BBD_reactionID:r1104 go-plus.json http://purl.obolibrary.org/obo/GO_0034803 GO:0010854 biolink:MolecularActivity adenylate cyclase regulator activity Binds to and modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010854 GO:0044235 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044235 GO:0034804 biolink:MolecularActivity benzo(a)pyrene 11,12-epoxidase activity Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide. UM-BBD_reactionID:r1119 go-plus.json http://purl.obolibrary.org/obo/GO_0034804 GO:0044232 biolink:CellularComponent organelle membrane contact site A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions. go-plus.json interorganelle junction|MCS|inter-organelle junction http://purl.obolibrary.org/obo/GO_0044232 GO:0010859 biolink:MolecularActivity calcium-dependent cysteine-type endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner. go-plus.json http://purl.obolibrary.org/obo/GO_0010859 GO:0044233 biolink:CellularComponent mitochondria-associated endoplasmic reticulum membrane A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange. go-plus.json mitochondria-associated ER membrane|mitochondria-endoplasmic reticulum (ER) contact|endoplasmic reticulum-mitochondrion membrane contact site|MAM|ER-mitochondrion membrane contact site|mitochondria-associated membrane|Mitochondria-associated Membrane http://purl.obolibrary.org/obo/GO_0044233 GO:0034805 biolink:MolecularActivity benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-. UM-BBD_reactionID:r1121 go-plus.json http://purl.obolibrary.org/obo/GO_0034805 GO:0010857 biolink:MolecularActivity calcium-dependent protein kinase activity Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. Reactome:R-HSA-8986937|Reactome:R-HSA-9005561 go-plus.json http://purl.obolibrary.org/obo/GO_0010857 GO:0044230 biolink:CellularComponent host cell envelope An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present. go-plus.json http://purl.obolibrary.org/obo/GO_0044230 GO:0034806 biolink:MolecularActivity benzo(a)pyrene 11,12-dioxygenase activity Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol. EC:1.13.11.-|UM-BBD_reactionID:r1124 go-plus.json http://purl.obolibrary.org/obo/GO_0034806 GO:0034807 biolink:MolecularActivity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene. UM-BBD_reactionID:r1131 go-plus.json http://purl.obolibrary.org/obo/GO_0034807 GO:0044231 biolink:CellularComponent host cell presynaptic membrane A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. go-plus.json other organism presynaptic membrane|other organism pre-synaptic membrane|host cell pre-synaptic membrane http://purl.obolibrary.org/obo/GO_0044231 GO:0010858 biolink:MolecularActivity calcium-dependent protein kinase regulator activity Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner. go-plus.json http://purl.obolibrary.org/obo/GO_0010858 GO:0009860 biolink:BiologicalProcess pollen tube growth Growth of pollen via tip extension of the intine wall. go-plus.json http://purl.obolibrary.org/obo/GO_0009860 GO:0009861 biolink:BiologicalProcess jasmonic acid and ethylene-dependent systemic resistance The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen. go-plus.json jasmonic acid/ethylene-dependent systemic resistance|jasmonic acid and ethene-dependent systemic resistance http://purl.obolibrary.org/obo/GO_0009861 GO:0009862 biolink:BiologicalProcess systemic acquired resistance, salicylic acid mediated signaling pathway The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance. go-plus.json systemic acquired resistance, salicylic acid mediated signalling pathway|salicylic acid mediated signaling pathway (systemic acquired resistance) http://purl.obolibrary.org/obo/GO_0009862 GO:0010851 biolink:MolecularActivity cyclase regulator activity Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0010851 GO:0009863 biolink:BiologicalProcess salicylic acid mediated signaling pathway A series of molecular signals mediated by salicylic acid. go-plus.json salicylic acid mediated signalling pathway|salicylic acid-mediated signaling pathway|salicylic acid mediated signal transduction http://purl.obolibrary.org/obo/GO_0009863 GO:0010852 biolink:MolecularActivity cyclase inhibitor activity Decreases the activity of an enzyme that catalyzes a ring closure reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0010852 GO:0044238 biolink:BiologicalProcess primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. go-plus.json primary metabolism http://purl.obolibrary.org/obo/GO_0044238 goslim_pir GO:0009864 biolink:BiologicalProcess induced systemic resistance, jasmonic acid mediated signaling pathway The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance. go-plus.json jasmonic acid mediated signaling pathway (induced systemic resistance)|induced systemic resistance, jasmonic acid mediated signalling pathway http://purl.obolibrary.org/obo/GO_0009864 GO:0010850 biolink:BiologicalProcess regulation of blood pressure by chemoreceptor signaling pathway A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. go-plus.json regulation of blood pressure by chemoreceptor signalling pathway http://purl.obolibrary.org/obo/GO_0010850 GO:0009865 biolink:BiologicalProcess pollen tube adhesion The process in which the pollen tube adheres to cells of the stigma and style. go-plus.json http://purl.obolibrary.org/obo/GO_0009865 GO:0044239 biolink:BiologicalProcess obsolete salivary polysaccharide catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth. go-plus.json salivary polysaccharide degradation|salivary polysaccharide breakdown|salivary polysaccharide catabolism http://purl.obolibrary.org/obo/GO_0044239 GO:0009866 biolink:BiologicalProcess induced systemic resistance, ethylene mediated signaling pathway The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance. go-plus.json induced systemic resistance, ethylene mediated signalling pathway|ethylene mediated signaling pathway (induced systemic resistance)|induced systemic resistance, ethene mediated signalling pathway|ethene mediated signaling pathway (induced systemic resistance)|induced systemic resistance, ethene mediated signaling pathway http://purl.obolibrary.org/obo/GO_0009866 GO:0009867 biolink:BiologicalProcess jasmonic acid mediated signaling pathway A series of molecular signals mediated by jasmonic acid. go-plus.json jasmonate signaling|jasmonic acid mediated signalling pathway|JA signaling http://purl.obolibrary.org/obo/GO_0009867 GO:0009868 biolink:BiologicalProcess jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance. go-plus.json jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid and ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance) http://purl.obolibrary.org/obo/GO_0009868 GO:0009869 biolink:BiologicalProcess obsolete incompatible pollen-pistil interaction OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth. go-plus.json incompatible pollen-pistil interaction http://purl.obolibrary.org/obo/GO_0009869 CHEBI:23696 biolink:ChemicalSubstance dichloroaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_23696 GO:0044240 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044240 CHEBI:23697 biolink:ChemicalSubstance dichlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23697 GO:0010828 biolink:BiologicalProcess positive regulation of glucose transmembrane transport Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json positive regulation of glucose transport http://purl.obolibrary.org/obo/GO_0010828 GO:0010829 biolink:BiologicalProcess negative regulation of glucose transmembrane transport Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json negative regulation of glucose transport http://purl.obolibrary.org/obo/GO_0010829 CHEBI:23698 biolink:ChemicalSubstance dichlorobenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_23698 CHEBI:23699 biolink:ChemicalSubstance dichlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23699 GO:0044247 biolink:BiologicalProcess cellular polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells. go-plus.json cellular polysaccharide degradation|cellular polysaccharide breakdown|cellular polysaccharide catabolism http://purl.obolibrary.org/obo/GO_0044247 CHEBI:33019 biolink:ChemicalSubstance diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33019 chebi_ph7_3 GO:0010822 biolink:BiologicalProcess positive regulation of mitochondrion organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. go-plus.json positive regulation of mitochondrion organisation http://purl.obolibrary.org/obo/GO_0010822 GO:0044248 biolink:BiologicalProcess cellular catabolic process The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. go-plus.json cellular catabolism|cellular degradation|cellular breakdown http://purl.obolibrary.org/obo/GO_0044248 GO:0010823 biolink:BiologicalProcess negative regulation of mitochondrion organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. go-plus.json negative regulation of mitochondrion organisation http://purl.obolibrary.org/obo/GO_0010823 GO:0010820 biolink:BiologicalProcess positive regulation of T cell chemotaxis Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010820 GO:0044245 biolink:BiologicalProcess polysaccharide digestion The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044245 GO:0044246 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044246 GO:0010821 biolink:BiologicalProcess regulation of mitochondrion organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. go-plus.json regulation of mitochondrion organisation http://purl.obolibrary.org/obo/GO_0010821 GO:0044243 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044243 GO:0010826 biolink:BiologicalProcess negative regulation of centrosome duplication Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010826 GO:0044244 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044244 GO:0010827 biolink:BiologicalProcess regulation of glucose transmembrane transport Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of glucose transport http://purl.obolibrary.org/obo/GO_0010827 GO:0044241 biolink:BiologicalProcess lipid digestion The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044241 GO:0010824 biolink:BiologicalProcess regulation of centrosome duplication Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010824 CHEBI:23690 biolink:ChemicalSubstance dicarboxylic acid amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23690 GO:0044242 biolink:BiologicalProcess cellular lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells. go-plus.json cellular lipid degradation|cellular lipid breakdown|cellular lipid catabolism http://purl.obolibrary.org/obo/GO_0044242 GO:0010825 biolink:BiologicalProcess positive regulation of centrosome duplication Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010825 PO:0008030 biolink:OntologyClass trichome cell A plant cell (PO:0009002) that is part of a multicellular trichome (PO:0000282). go-plus.json 毛（毛茸、糸状体）細胞 (Japanese, exact)|célula del tricoma (Spanish, exact) http://purl.obolibrary.org/obo/PO_0008030 GO:0009830 biolink:BiologicalProcess cell wall modification involved in abscission A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission. go-plus.json cell wall modification during abscission http://purl.obolibrary.org/obo/GO_0009830 GO:0009831 biolink:BiologicalProcess plant-type cell wall modification involved in multidimensional cell growth The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana. go-plus.json cell wall modification during cell expansion|cellulose and pectin-containing cell wall modification during multidimensional cell growth http://purl.obolibrary.org/obo/GO_0009831 CHEBI:33017 biolink:ChemicalSubstance diphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33017 GO:0044249 biolink:BiologicalProcess cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. go-plus.json cellular biosynthesis|cellular anabolism|cellular synthesis|cellular formation http://purl.obolibrary.org/obo/GO_0044249 GO:0009832 biolink:BiologicalProcess plant-type cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana. go-plus.json cell wall formation|cellulose and pectin-containing cell wall biogenesis|cell wall biosynthetic process|cell wall anabolism|cell wall assembly|cell wall synthesis http://purl.obolibrary.org/obo/GO_0009832 GO:0009833 biolink:BiologicalProcess plant-type primary cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana. go-plus.json primary cell wall formation|cellulose and pectin-containing primary cell wall biogenesis|primary cell wall anabolism|primary cell wall biosynthetic process|primary cell wall biogenesis|primary cell wall synthesis http://purl.obolibrary.org/obo/GO_0009833 GO:0009834 biolink:BiologicalProcess plant-type secondary cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana. go-plus.json secondary cell wall anabolism|secondary cell wall biosynthetic process|secondary cell wall synthesis|secondary cell wall biogenesis|secondary cell wall formation|cellulose and pectin-containing secondary cell wall biogenesis http://purl.obolibrary.org/obo/GO_0009834 GO:0009835 biolink:BiologicalProcess fruit ripening An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal. Wikipedia:Ripening go-plus.json fruit senescence|fruit maturation http://purl.obolibrary.org/obo/GO_0009835 goslim_plant GO:0009836 biolink:BiologicalProcess fruit ripening, climacteric A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset. go-plus.json http://purl.obolibrary.org/obo/GO_0009836 GO:0009837 biolink:BiologicalProcess fruit ripening, non-climacteric A fruit ripening process that does not involve a respiratory burst. go-plus.json http://purl.obolibrary.org/obo/GO_0009837 GO:0009838 biolink:BiologicalProcess abscission The controlled shedding of a body part. Wikipedia:Abscission go-plus.json http://purl.obolibrary.org/obo/GO_0009838 goslim_plant GO:0009839 biolink:CellularComponent obsolete SCF complex substrate recognition subunit OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex. go-plus.json SCF complex substrate recognition subunit http://purl.obolibrary.org/obo/GO_0009839 CHEBI:33010 biolink:ChemicalSubstance chromide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33010 GO:0044250 biolink:BiologicalProcess negative regulation of metabolic activity involved in hibernation The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation. go-plus.json down regulation of metabolic activity during hibernation|downregulation of metabolic activity during hibernation|negative regulation of metabolic activity during hibernation|down-regulation of metabolic activity during hibernation|inhibition of metabolic activity during hibernation http://purl.obolibrary.org/obo/GO_0044250 GO:0044251 biolink:BiologicalProcess obsolete protein catabolic process by pepsin OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid). go-plus.json protein degradation by pepsin|protein breakdown by pepsin http://purl.obolibrary.org/obo/GO_0044251 GO:0010839 biolink:BiologicalProcess negative regulation of keratinocyte proliferation Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0010839 GO:0044258 biolink:BiologicalProcess intestinal lipid catabolic process The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. go-plus.json intestinal lipid breakdown|intestinal lipid degradation|intestinal lipid catabolism http://purl.obolibrary.org/obo/GO_0044258 GO:0010833 biolink:BiologicalProcess telomere maintenance via telomere lengthening Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0010833 GO:0044259 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044259 GO:0010834 biolink:BiologicalProcess obsolete telomere maintenance via telomere shortening OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA. go-plus.json telomere maintenance via telomere shortening http://purl.obolibrary.org/obo/GO_0010834 GO:0044256 biolink:BiologicalProcess protein digestion The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044256 GO:0010831 biolink:BiologicalProcess positive regulation of myotube differentiation Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0010831 GO:0010832 biolink:BiologicalProcess negative regulation of myotube differentiation Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0010832 GO:0044257 biolink:BiologicalProcess cellular protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. go-plus.json cellular protein degradation|cellular protein breakdown|cellular protein catabolism http://purl.obolibrary.org/obo/GO_0044257 GO:0044254 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044254 GO:0010837 biolink:BiologicalProcess regulation of keratinocyte proliferation Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0010837 GO:0044255 biolink:BiologicalProcess cellular lipid metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells. go-plus.json cellular lipid metabolism http://purl.obolibrary.org/obo/GO_0044255 goslim_pir GO:0010838 biolink:BiologicalProcess positive regulation of keratinocyte proliferation Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0010838 GO:0010835 biolink:BiologicalProcess regulation of protein ADP-ribosylation Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids. go-plus.json regulation of protein amino acid ADP-ribosylation http://purl.obolibrary.org/obo/GO_0010835 GO:0044252 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044252 GO:0010836 biolink:BiologicalProcess negative regulation of protein ADP-ribosylation Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids. go-plus.json negative regulation of protein amino acid ADP-ribosylation http://purl.obolibrary.org/obo/GO_0010836 GO:0044253 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044253 GO:0009840 biolink:CellularComponent chloroplastic endopeptidase Clp complex A Clp endopeptidase complex located in the chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0009840 GO:0010830 biolink:BiologicalProcess regulation of myotube differentiation Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0010830 GO:0009841 biolink:CellularComponent mitochondrial endopeptidase Clp complex A Clp endopeptidase complex located in the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0009841 GO:0009842 biolink:CellularComponent cyanelle A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid. go-plus.json muroplast|cyanoplast http://purl.obolibrary.org/obo/GO_0009842 GO:0009843 biolink:CellularComponent cyanelle thylakoid A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0009843 GO:0009844 biolink:BiologicalProcess obsolete germination OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth. go-plus.json germination http://purl.obolibrary.org/obo/GO_0009844 GO:0009845 biolink:BiologicalProcess seed germination The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis. Wikipedia:Germination#Seed_germination go-plus.json http://purl.obolibrary.org/obo/GO_0009845 GO:0009846 biolink:BiologicalProcess pollen germination The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture. go-plus.json http://purl.obolibrary.org/obo/GO_0009846 PO:0008028 biolink:OntologyClass reproductive shoot apical meristem A shoot apical meristem (PO:0020148) that gives rise to the apical growth of reproductive tissues and organs. go-plus.json 生殖シュート頂端 分裂組織 (Japanese, exact)|meristema apical reproductivo del epiblasto (epiblastema) (Spanish, exact) http://purl.obolibrary.org/obo/PO_0008028 GO:0009847 biolink:BiologicalProcess spore germination The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall). go-plus.json spore germination on or near host http://purl.obolibrary.org/obo/GO_0009847 GO:0009848 biolink:BiologicalProcess indoleacetic acid biosynthetic process via tryptophan The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan. MetaCyc:PWY-581 go-plus.json indoleacetic acid formation via tryptophan|indoleacetic acid synthesis via tryptophan|indoleacetic acid anabolism via tryptophan|IAA biosynthetic process via tryptophan http://purl.obolibrary.org/obo/GO_0009848 GO:0009849 biolink:BiologicalProcess tryptophan-independent indoleacetic acid biosynthetic process The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan. MetaCyc:PWY-581 go-plus.json tryptophan-independent indoleacetic acid biosynthesis|tryptophan-independent IAA biosynthetic process|tryptophan-independent indoleacetic acid synthesis|tryptophan-independent indoleacetic acid formation|indoleacetic acid biosynthetic process, tryptophan-independent|indoleacetic acid biosynthesis, tryptophan-independent|tryptophan-independent indoleacetic acid anabolism http://purl.obolibrary.org/obo/GO_0009849 CHEBI:33020 biolink:ChemicalSubstance kojibiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_33020 chebi_ph7_3 CHEBI:139160 biolink:ChemicalSubstance 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139160 CHEBI:139161 biolink:ChemicalSubstance 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139161 chebi_ph7_3 CHEBI:139162 biolink:ChemicalSubstance oleuropein aglycone go-plus.json http://purl.obolibrary.org/obo/CHEBI_139162 chebi_ph7_3 CHEBI:139163 biolink:ChemicalSubstance 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_139163 CHEBI:72600 biolink:ChemicalSubstance spiroketal go-plus.json http://purl.obolibrary.org/obo/CHEBI_72600 CHEBI:140157 biolink:ChemicalSubstance 8-carboxy-8-demethylriboflavin 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140157 CHEBI:72606 biolink:ChemicalSubstance 11-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72606 CHEBI:72608 biolink:ChemicalSubstance (4Z,7Z,10Z,14E,16Z,19Z)-13-hydroxydocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72608 CHEBI:140156 biolink:ChemicalSubstance 8-formyl-8-demethylriboflavin 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140156 CHEBI:140153 biolink:ChemicalSubstance (9Z,12R)-12-hydroxyoctadec-9-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_140153 CHEBI:140159 biolink:ChemicalSubstance D-hexose phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140159 chebi_ph7_3 CHEBI:139157 biolink:ChemicalSubstance (S,S)-2-oleoylglycero-1-phospho-1'-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139157 chebi_ph7_3 CHEBI:139158 biolink:ChemicalSubstance [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139158 chebi_ph7_3 CHEBI:139159 biolink:ChemicalSubstance alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139159 chebi_ph7_3 GO:0019298 biolink:BiologicalProcess coenzyme B biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. MetaCyc:P241-PWY go-plus.json coenzyme B anabolism|coenzyme B synthesis|coenzyme B formation|coenzyme B biosynthesis http://purl.obolibrary.org/obo/GO_0019298 CHEBI:139154 biolink:ChemicalSubstance AZD1979 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139154 GO:0019299 biolink:BiologicalProcess rhamnose metabolic process The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids. go-plus.json rhamnose metabolism http://purl.obolibrary.org/obo/GO_0019299 GO:0019296 biolink:BiologicalProcess coenzyme M metabolic process The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. go-plus.json coenzyme M metabolism http://purl.obolibrary.org/obo/GO_0019296 CHEBI:139155 biolink:ChemicalSubstance melanin-concentrating hormone receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_139155 CHEBI:139156 biolink:ChemicalSubstance (S,S)-bis-(2-oleoylglycero)-1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139156 chebi_ph7_3 GO:0019297 biolink:BiologicalProcess coenzyme B metabolic process The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. go-plus.json coenzyme B metabolism http://purl.obolibrary.org/obo/GO_0019297 CHEBI:139171 biolink:ChemicalSubstance N(2)-[(3R)-3-(2-hydroxyacyloxy)acyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139171 chebi_ph7_3 CHEBI:139164 biolink:ChemicalSubstance 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139164 chebi_ph7_3 CHEBI:139166 biolink:ChemicalSubstance secoiridoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139166 GO:0019283 biolink:BiologicalProcess L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine. go-plus.json L-methionine anabolism from O-phospho-L-homoserine and cystathionine|L-methionine synthesis from O-phospho-L-homoserine and cystathionine|L-methionine formation from O-phospho-L-homoserine and cystathionine|methionine biosynthetic process from O-phospho-L-homoserine and cystathionine http://purl.obolibrary.org/obo/GO_0019283 GO:0019284 biolink:BiologicalProcess L-methionine salvage from S-adenosylmethionine The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine. go-plus.json L-methionine synthesis from S-adenosylmethionine|L-methionine formation from S-adenosylmethionine http://purl.obolibrary.org/obo/GO_0019284 GO:0019281 biolink:BiologicalProcess L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine. MetaCyc:MET-SAM-PWY go-plus.json L-methionine anabolism from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-succinyl-L-homoserine and cystathionine|methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine http://purl.obolibrary.org/obo/GO_0019281 GO:0019282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019282 GO:0103100 biolink:MolecularActivity UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-). EC:2.4.1.195|MetaCyc:RXNQT-4325 go-plus.json http://purl.obolibrary.org/obo/GO_0103100 GO:0103101 biolink:MolecularActivity UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP. EC:2.4.1.195|MetaCyc:RXNQT-4326 go-plus.json http://purl.obolibrary.org/obo/GO_0103101 GO:0019280 biolink:BiologicalProcess L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine. MetaCyc:HSERMETANA-PWY go-plus.json methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-acetyl-L-homoserine and cystathionine http://purl.obolibrary.org/obo/GO_0019280 GO:0103104 biolink:MolecularActivity 6-methylthiohexyldesulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate. MetaCyc:RXNQT-4331 go-plus.json http://purl.obolibrary.org/obo/GO_0103104 CHEBI:140135 biolink:ChemicalSubstance 8-amino-8-demethylriboflavin 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140135 CHEBI:72627 biolink:ChemicalSubstance 15-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72627 GO:0103105 biolink:MolecularActivity 2-oxo-6-methylthiohexanoate aminotransferase activity Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate. MetaCyc:RXNQT-4345 go-plus.json http://purl.obolibrary.org/obo/GO_0103105 GO:0103102 biolink:MolecularActivity UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP. EC:2.4.1.195|MetaCyc:RXNQT-4327 go-plus.json http://purl.obolibrary.org/obo/GO_0103102 GO:0103103 biolink:MolecularActivity UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+. EC:2.4.1.195|MetaCyc:RXNQT-4328 go-plus.json http://purl.obolibrary.org/obo/GO_0103103 GO:0103106 biolink:MolecularActivity brassinolide 23-O-glucosyltransferase activity Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose <=> brassinolide-23-O-glucoside + UDP + H+. MetaCyc:RXNQT-4397 go-plus.json http://purl.obolibrary.org/obo/GO_0103106 GO:0103107 biolink:MolecularActivity castasterone 23-O-glucosyltransferase activity Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+. MetaCyc:RXNQT-4398 go-plus.json http://purl.obolibrary.org/obo/GO_0103107 GO:0019278 biolink:BiologicalProcess UDP-N-acetylgalactosamine catabolic process The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. go-plus.json UDP-N-acetylgalactosamine catabolism|UDP-N-acetylgalactosamine degradation|UDP-N-acetylgalactosamine breakdown http://purl.obolibrary.org/obo/GO_0019278 GO:0019279 biolink:BiologicalProcess L-methionine biosynthetic process from L-homoserine via cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine. MetaCyc:HOMOSER-METSYN-PWY go-plus.json methionine biosynthetic process from L-homoserine via cystathionine|L-methionine anabolism from L-homoserine via cystathionine|L-methionine synthesis from L-homoserine via cystathionine|L-methionine formation from L-homoserine via cystathionine http://purl.obolibrary.org/obo/GO_0019279 GO:0019276 biolink:BiologicalProcess UDP-N-acetylgalactosamine metabolic process The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. go-plus.json UDP-N-acetylgalactosamine metabolism http://purl.obolibrary.org/obo/GO_0019276 GO:0019277 biolink:BiologicalProcess UDP-N-acetylgalactosamine biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. MetaCyc:UDPNACETYLGALSYN-PWY go-plus.json UDP-N-acetylgalactosamine biosynthesis|UDP-N-acetylgalactosamine anabolism|UDP-N-acetylgalactosamine synthesis|UDP-N-acetylgalactosamine formation http://purl.obolibrary.org/obo/GO_0019277 GO:0019274 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019274 GO:0019275 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019275 GO:0019294 biolink:BiologicalProcess keto-3-deoxy-D-manno-octulosonic acid biosynthetic process The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria. MetaCyc:KDOSYN-PWY go-plus.json keto-3-deoxy-D-manno-octulosonic acid synthesis|keto-3-deoxy-D-manno-octulosonic acid formation|ketodeoxyoctanoate biosynthetic process|keto-3-deoxy-D-manno-octulosonic acid biosynthesis|KDO biosynthetic process|KDO biosynthesis|keto-3-deoxy-D-manno-octulosonic acid anabolism http://purl.obolibrary.org/obo/GO_0019294 GO:0019295 biolink:BiologicalProcess coenzyme M biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. MetaCyc:P261-PWY go-plus.json coenzyme M formation|coenzyme M biosynthesis|coenzyme M anabolism|coenzyme M synthesis http://purl.obolibrary.org/obo/GO_0019295 CHEBI:139150 biolink:ChemicalSubstance (S,S)-bis-(3-oleoylglycero)-1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139150 chebi_ph7_3 CHEBI:139151 biolink:ChemicalSubstance ADP-5-ethyl-4-methylthiazole-2-carboxylate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139151 chebi_ph7_3 GO:0019292 biolink:BiologicalProcess tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate. MetaCyc:TYRSYN go-plus.json tyrosine biosynthetic process from chorismate via p-hydroxyphenylpyruvate|tyrosine anabolism from chorismate via 4-hydroxyphenylpyruvate|tyrosine synthesis from chorismate via 4-hydroxyphenylpyruvate|tyrosine formation from chorismate via 4-hydroxyphenylpyruvate http://purl.obolibrary.org/obo/GO_0019292 GO:0019293 biolink:BiologicalProcess tyrosine biosynthetic process, by oxidation of phenylalanine The conversion of phenylalanine to tyrosine. MetaCyc:PWY-6134 go-plus.json tyrosine anabolism, by oxidation of phenylalanine|L-tyrosine biosynthesis IV|tyrosine formation, by oxidation of phenylalanine|tyrosine synthesis, by oxidation of phenylalanine http://purl.obolibrary.org/obo/GO_0019293 CHEBI:139152 biolink:ChemicalSubstance (S,S)-3-oleoylglycero-1-phospho-1'-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139152 chebi_ph7_3 GO:0019290 biolink:BiologicalProcess siderophore biosynthetic process The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. go-plus.json siderophore formation|siderochrome biosynthesis|siderochrome biosynthetic process|siderophore biosynthetic process, peptide formation|siderophore biosynthetic process, peptide modification|siderophore biosynthesis|siderophore anabolism|siderophore synthesis http://purl.obolibrary.org/obo/GO_0019290 GO:0103111 biolink:MolecularActivity D-glucosamine PTS permease activity Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine. EC:2.7.1.69|MetaCyc:TRANS-RXN-167A|RHEA:37359 go-plus.json http://purl.obolibrary.org/obo/GO_0103111 GO:0019291 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019291 CHEBI:72637 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72637 GO:0103115 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103115 GO:0103116 biolink:MolecularActivity ABC-type D-galactofuranose transporter Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+. MetaCyc:TRANS-RXN0-491|RHEA:61716|EC:7.5.2.9 go-plus.json ATP-dependent alpha-D-galactofuranose transporter activity|ATPase-coupled alpha-D-galactofuranose transporter activity|alpha-D-galactofuranose transporter activity http://purl.obolibrary.org/obo/GO_0103116 CHEBI:72639 biolink:ChemicalSubstance 13-HODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72639 GO:0103113 biolink:MolecularActivity obsolete glucosyl-oleandomycin-exporting ATPase activity OBSOLETE. Catalysis of the reaction: glucosyl-oleandomycin + ATP + H2O <=> glucosyl-oleandomycin + ADP + hydrogenphosphate + H+. MetaCyc:TRANS-RXN-220 go-plus.json http://purl.obolibrary.org/obo/GO_0103113 GO:0103117 biolink:MolecularActivity UDP-3-O-acyl-N-acetylglucosamine deacetylase activity Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate. MetaCyc:UDPACYLGLCNACDEACETYL-RXN|RHEA:25209|EC:3.5.1.108 go-plus.json http://purl.obolibrary.org/obo/GO_0103117 GO:0103118 biolink:MolecularActivity UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein]. EC:2.3.1.191|MetaCyc:UDPHYDROXYMYRGLUCOSAMNACETYLTRANS-RXN|RHEA:17817 go-plus.json UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity http://purl.obolibrary.org/obo/GO_0103118 CHEBI:139146 biolink:ChemicalSubstance 4-O-({poly[2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphosphonato]}-di{[2R]-1-glycerylphosphonato})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139146 chebi_ph7_3 CHEBI:139147 biolink:ChemicalSubstance mannose-1D-myo-inositol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139147 chebi_ph7_3 GO:0019289 biolink:BiologicalProcess rhizobactin 1021 biosynthetic process The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti. MetaCyc:PWY-761 go-plus.json rhizobactin 1021 anabolism|rhizobactin 1021 synthesis|rhizobactin 1021 formation|rhizobactin 1021 biosynthetic process, peptide modification|rhizobactin 1021 biosynthesis|rhizobactin 1021 biosynthetic process, peptide formation http://purl.obolibrary.org/obo/GO_0019289 CHEBI:139148 biolink:ChemicalSubstance mannose-(1D-myo-inositol 1-phosphate)2(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139148 chebi_ph7_3 CHEBI:139149 biolink:ChemicalSubstance 4-O-[poly(2-beta-D-glucosyl-1-D-ribitylphosphonato)-1-D-ribitylphosphonato-(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139149 chebi_ph7_3 GO:0019287 biolink:BiologicalProcess isopentenyl diphosphate biosynthetic process, mevalonate pathway The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates. go-plus.json isopentenyl diphosphate biosynthetic process via mevalonate|isopentenyl diphosphate anabolism, mevalonate pathway|acetate-mevalonate pathway|isopentenyl diphosphate synthesis, mevalonate pathway|isopentenyl diphosphate formation, mevalonate pathway|Ac-MVA pathway http://purl.obolibrary.org/obo/GO_0019287 GO:0019288 biolink:BiologicalProcess isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. MetaCyc:NONMEVIPP-PWY go-plus.json isopentenyl diphosphate formation, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, MEP pathway|isopentenyl diphosphate biosynthetic process via 1-deoxy-D-xylulose 5-phosphate|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, mevalonate-independent|isopentenyl diphosphate anabolism, mevalonate-independent pathway|isopentenyl diphosphate biosynthesis, mevalonate-independent|non-MVA pathway|mevalonate-independent isopentenyl diphosphate biosynthetic process|mevalonate-independent isopentenyl diphosphate biosynthesis|isopentenyl diphosphate biosynthetic process, non-mevalonate pathway|isopentenyl diphosphate biosynthesis, non-mevalonate pathway|isopentenyl diphosphate synthesis, mevalonate-independent pathway http://purl.obolibrary.org/obo/GO_0019288 GO:0019285 biolink:BiologicalProcess glycine betaine biosynthetic process from choline The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline. MetaCyc:P542-PWY|MetaCyc:BETSYN-PWY|MetaCyc:CHOLINE-BETAINE-ANA-PWY go-plus.json glycine betaine formation from choline|glycine betaine synthesis from choline|glycine betaine anabolism from choline|choline oxidation|N-trimethylglycine biosynthetic process from choline|N-trimethylglycine biosynthesis from choline http://purl.obolibrary.org/obo/GO_0019285 GO:0019286 biolink:BiologicalProcess glycine betaine biosynthetic process from glycine The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine. MetaCyc:P541-PWY go-plus.json N-trimethylglycine biosynthetic process from glycine|N-trimethylglycine biosynthesis from glycine|glycine betaine formation from glycine|glycine betaine synthesis from glycine|glycine betaine anabolism from glycine http://purl.obolibrary.org/obo/GO_0019286 CHEBI:139145 biolink:ChemicalSubstance 4-O-({poly[2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphosphonato]}-di{[2R]-1-glycerylphosphonato})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139145 chebi_ph7_3 GO:0019261 biolink:BiologicalProcess 1,4-dichlorobenzene catabolic process The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. MetaCyc:14DICHLORBENZDEG-PWY go-plus.json 1,4-dichlorobenzene degradation|1,4-dichlorobenzene breakdown|1,4-dichlorobenzene catabolism http://purl.obolibrary.org/obo/GO_0019261 GO:0019262 biolink:BiologicalProcess N-acetylneuraminate catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. MetaCyc:P441-PWY go-plus.json N-acetylneuraminate degradation|N-acetylneuraminate breakdown|N-acetylneuraminate catabolism http://purl.obolibrary.org/obo/GO_0019262 CHEBI:72643 biolink:ChemicalSubstance 8-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72643 GO:0019260 biolink:BiologicalProcess 1,2-dichloroethane catabolic process The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. MetaCyc:12DICHLORETHDEG-PWY go-plus.json 1,2-dichloroethane catabolism|1,2-dichloroethane degradation|1,2-dichloroethane breakdown http://purl.obolibrary.org/obo/GO_0019260 CHEBI:72646 biolink:ChemicalSubstance (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_72646 chebi_ph7_3 CHEBI:72647 biolink:ChemicalSubstance 14-HDoHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72647 CHEBI:72648 biolink:ChemicalSubstance (3R)-7,2'-dihydroxy-4'-methoxyisoflavanol 4-oxonium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_72648 GO:0034899 biolink:MolecularActivity trimethylamine monooxygenase activity Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O. EC:1.14.13.148|UM-BBD_reactionID:r1407|RHEA:31979|KEGG_REACTION:R05623 go-plus.json http://purl.obolibrary.org/obo/GO_0034899 CHEBI:72649 biolink:ChemicalSubstance cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72649 chebi_ph7_3 GO:0034891 biolink:MolecularActivity endosulfan diol dehydrogenase activity Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-. UM-BBD_reactionID:r1388 go-plus.json http://purl.obolibrary.org/obo/GO_0034891 GO:0034892 biolink:MolecularActivity endosulfan lactone lactonase activity Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+. UM-BBD_reactionID:r1389 go-plus.json http://purl.obolibrary.org/obo/GO_0034892 GO:0034893 biolink:MolecularActivity N-nitrodimethylamine hydroxylase activity Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O. UM-BBD_reactionID:r1395 go-plus.json http://purl.obolibrary.org/obo/GO_0034893 GO:0034894 biolink:MolecularActivity 4-hydroxypyridine-3-hydroxylase activity Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+. EC:1.14.13.-|UM-BBD_reactionID:r1397 go-plus.json http://purl.obolibrary.org/obo/GO_0034894 GO:0034895 biolink:MolecularActivity pyridine-3,4-diol dioxygenase activity Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate. EC:1.13.11.-|UM-BBD_reactionID:r1398 go-plus.json http://purl.obolibrary.org/obo/GO_0034895 PR:000008534 biolink:Protein hepatocyte growth factor A protein that is a translation product of the human HGF gene or a 1:1 ortholog thereof. go-plus.json HPTA|HGF|hepatopoeitin-A|SF|scatter factor http://purl.obolibrary.org/obo/PR_000008534 GO:0034896 biolink:MolecularActivity 3-formiminopyruvate hydrolase activity Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3. UM-BBD_reactionID:r1400|EC:3.5.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034896 GO:0034897 biolink:MolecularActivity 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol. UM-BBD_reactionID:r1358 go-plus.json http://purl.obolibrary.org/obo/GO_0034897 GO:0034898 biolink:MolecularActivity hexadecyltrimethylammonium chloride monooxygenase activity Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O. UM-BBD_reactionID:r1373|EC:1.13.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0034898 GO:0019258 biolink:BiologicalProcess 4-nitrotoluene catabolic process The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene. MetaCyc:P421-PWY go-plus.json 4-nitrotoluene degradation|4-nitrotoluene breakdown|4NT catabolic process|4NT catabolism|4-nitrotoluene catabolism http://purl.obolibrary.org/obo/GO_0019258 GO:0019259 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019259 CHEBI:139114 biolink:ChemicalSubstance carotenoid psi-end group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139114 chebi_ph7_3 GO:0019256 biolink:BiologicalProcess acrylonitrile catabolic process The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers. MetaCyc:P344-PWY go-plus.json acrylonitrile catabolism|acrylonitrile degradation|acrylonitrile breakdown http://purl.obolibrary.org/obo/GO_0019256 CHEBI:139115 biolink:ChemicalSubstance carotenoid epsilon-end group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139115 chebi_ph7_3 GO:0019257 biolink:BiologicalProcess 4-nitrotoluene metabolic process The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor. go-plus.json 4NT metabolism|4-nitrotoluene metabolism|4NT metabolic process http://purl.obolibrary.org/obo/GO_0019257 GO:0019254 biolink:BiologicalProcess carnitine metabolic process, CoA-linked The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA. MetaCyc:CARNMET-PWY go-plus.json carnitine metabolism, CoA-linked http://purl.obolibrary.org/obo/GO_0019254 GO:0019255 biolink:BiologicalProcess glucose 1-phosphate metabolic process The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1. MetaCyc:GLUCOSE1PMETAB-PWY go-plus.json glucose 1-phosphate utilization|glucose 1-phosphate metabolism http://purl.obolibrary.org/obo/GO_0019255 CHEBI:139110 biolink:ChemicalSubstance (R,R)-3-(3-hydroxydecanoyloxy)decanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139110 GO:0019252 biolink:BiologicalProcess starch biosynthetic process The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants. MetaCyc:PWY-622 go-plus.json starch anabolism|starch synthesis|starch formation|starch biosynthesis http://purl.obolibrary.org/obo/GO_0019252 GO:0019253 biolink:BiologicalProcess reductive pentose-phosphate cycle The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate. MetaCyc:CALVIN-PWY go-plus.json Calvin cycle|C3 photosynthesis http://purl.obolibrary.org/obo/GO_0019253 GO:0034890 biolink:MolecularActivity endosulfan diol hydrolyase (cyclizing) activity Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O. UM-BBD_reactionID:r1386 go-plus.json http://purl.obolibrary.org/obo/GO_0034890 GO:0019272 biolink:BiologicalProcess L-alanine biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate. MetaCyc:ALANINE-SYN2-PWY|MetaCyc:ALANINE-VALINESYN-PWY go-plus.json L-alanine anabolism from pyruvate|L-alanine synthesis from pyruvate|L-alanine formation from pyruvate http://purl.obolibrary.org/obo/GO_0019272 CHEBI:72653 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72653 GO:0019273 biolink:BiologicalProcess L-alanine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine. go-plus.json L-alanine anabolism via ornithine|L-alanine synthesis via ornithine|L-alanine formation via ornithine http://purl.obolibrary.org/obo/GO_0019273 GO:0019270 biolink:BiologicalProcess aerobactin biosynthetic process The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid. MetaCyc:AEROBACTINSYN-PWY go-plus.json aerobactin synthesis|aerobactin formation|aerobactin biosynthesis|aerobactin anabolism http://purl.obolibrary.org/obo/GO_0019270 CHEBI:72654 biolink:ChemicalSubstance epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72654 CHEBI:139130 biolink:ChemicalSubstance carotenoid chi-end group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139130 chebi_ph7_3 GO:0019271 biolink:BiologicalProcess aerobactin transport The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid. go-plus.json http://purl.obolibrary.org/obo/GO_0019271 CHEBI:72659 biolink:ChemicalSubstance epoxyoctadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_72659 GO:0034888 biolink:MolecularActivity endosulfan monooxygenase I activity Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O. UM-BBD_reactionID:r1382 go-plus.json http://purl.obolibrary.org/obo/GO_0034888 GO:0034889 biolink:MolecularActivity endosulfan hemisulfate sulfatase activity Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate. UM-BBD_reactionID:r1384 go-plus.json http://purl.obolibrary.org/obo/GO_0034889 GO:0034880 biolink:MolecularActivity citrazinate dehydrogenase activity Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-. UM-BBD_reactionID:r1339 go-plus.json http://purl.obolibrary.org/obo/GO_0034880 GO:0034881 biolink:MolecularActivity citrazinate hydrolase activity Catalysis of the reaction: citrazinate + H2O = cis-aconitamide. UM-BBD_reactionID:r1343 go-plus.json http://purl.obolibrary.org/obo/GO_0034881 GO:0034882 biolink:MolecularActivity cis-aconitamide amidase activity Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3. UM-BBD_reactionID:r1344 go-plus.json http://purl.obolibrary.org/obo/GO_0034882 GO:0034883 biolink:MolecularActivity obsolete isonicotinate reductase activity OBSOLETE. Catalysis of the reaction: isonicotinate + 2 H+ + 2 e- = 1,4-dihydroisonicotinate. go-plus.json isonicotinate reductase activity http://purl.obolibrary.org/obo/GO_0034883 GO:0034884 biolink:MolecularActivity obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-. go-plus.json gamma-N-formylaminovinylacetaldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0034884 CHEBI:139129 biolink:ChemicalSubstance carotenoid phi-end group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139129 chebi_ph7_3 GO:0034885 biolink:MolecularActivity gamma-N-formylaminovinylacetate hydrolase activity Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH. UM-BBD_reactionID:r1350 go-plus.json http://purl.obolibrary.org/obo/GO_0034885 GO:0034886 biolink:MolecularActivity gamma-aminovinylacetate deaminase activity Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3. EC:3.5.99.-|UM-BBD_reactionID:r1351 go-plus.json http://purl.obolibrary.org/obo/GO_0034886 GO:0034887 biolink:MolecularActivity obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2. go-plus.json 1,4-dihydroisonicotinate 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0034887 GO:0019269 biolink:BiologicalProcess obsolete glutamate biosynthetic process, using glutamate synthase (NADPH) OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH). go-plus.json glutamate formation, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamate anabolism, using glutamate synthase (NADPH)|glutamate synthesis, using glutamate synthase (NADPH) http://purl.obolibrary.org/obo/GO_0019269 CHEBI:139124 biolink:ChemicalSubstance (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139124 GO:0019267 biolink:BiologicalProcess asparagine biosynthetic process from cysteine The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine. MetaCyc:ASPSYNII-PWY go-plus.json asparagine anabolism from cysteine|asparagine synthesis from cysteine|asparagine formation from cysteine http://purl.obolibrary.org/obo/GO_0019267 CHEBI:139126 biolink:ChemicalSubstance C-terminal S-carbamoyl-L-cysteinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139126 chebi_ph7_3 GO:0019268 biolink:BiologicalProcess obsolete glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+) OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate dehydrogenase (NADP+). go-plus.json glutamate anabolism, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate formation, using glutamate dehydrogenase (NAD(P)+)|glutamate synthesis, using glutamate dehydrogenase (NAD(P)+) http://purl.obolibrary.org/obo/GO_0019268 CHEBI:139127 biolink:ChemicalSubstance C-terminal S-cyano-L-cysteinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139127 chebi_ph7_3 GO:0019265 biolink:BiologicalProcess glycine biosynthetic process, by transamination of glyoxylate The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate. go-plus.json glycine formation, by transamination of glyoxylate|glycine synthesis, by transamination of glyoxylate|glycine anabolism, by transamination of glyoxylate http://purl.obolibrary.org/obo/GO_0019265 CHEBI:139120 biolink:ChemicalSubstance carotenoid beta-end group go-plus.json http://purl.obolibrary.org/obo/CHEBI_139120 chebi_ph7_3 GO:0019266 biolink:BiologicalProcess asparagine biosynthetic process from oxaloacetate The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate. MetaCyc:ASPARAGINE-BIOSYNTHESIS go-plus.json asparagine anabolism from oxaloacetate|asparagine synthesis from oxaloacetate|asparagine formation from oxaloacetate http://purl.obolibrary.org/obo/GO_0019266 CHEBI:139121 biolink:ChemicalSubstance (3E,5Z)-dodecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139121 GO:0019263 biolink:BiologicalProcess adamantanone catabolic process The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists. MetaCyc:P481-PWY go-plus.json adamantanone catabolism|adamantanone degradation|adamantanone breakdown http://purl.obolibrary.org/obo/GO_0019263 CHEBI:139122 biolink:ChemicalSubstance (3R)-3-hydroxy-2,3-dihydrotabersonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139122 CHEBI:72650 biolink:ChemicalSubstance cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72650 chebi_ph7_3 GO:0019264 biolink:BiologicalProcess glycine biosynthetic process from serine The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine. MetaCyc:GLYSYN-PWY go-plus.json glycine anabolism from serine|glycine synthesis from serine|glycine formation from serine http://purl.obolibrary.org/obo/GO_0019264 CHEBI:72651 biolink:ChemicalSubstance 9-HODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_72651 CHEBI:72663 biolink:ChemicalSubstance 9,10-DiHOME go-plus.json http://purl.obolibrary.org/obo/CHEBI_72663 GO:0019240 biolink:BiologicalProcess citrulline biosynthetic process The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. MetaCyc:CITRULBIO-PWY go-plus.json citrulline formation|citrulline biosynthesis|citrulline anabolism|citrulline synthesis http://purl.obolibrary.org/obo/GO_0019240 CHEBI:72665 biolink:ChemicalSubstance 12,13-DiHOME go-plus.json http://purl.obolibrary.org/obo/CHEBI_72665 GO:0034877 biolink:MolecularActivity isonicotinate dehydrogenase activity Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor. UM-BBD_reactionID:r1337 go-plus.json http://purl.obolibrary.org/obo/GO_0034877 GO:0034878 biolink:MolecularActivity 2-hydroxyisonicotinate dehydrogenase activity Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor. UM-BBD_reactionID:r1338 go-plus.json http://purl.obolibrary.org/obo/GO_0034878 GO:0034879 biolink:MolecularActivity 2,3,6-trihydroxyisonicotinate decarboxylase activity Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2. UM-BBD_reactionID:r1340 go-plus.json http://purl.obolibrary.org/obo/GO_0034879 GO:0034870 biolink:MolecularActivity pinacolone 5-monooxygenase activity Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one. UM-BBD_reactionID:r12979 go-plus.json http://purl.obolibrary.org/obo/GO_0034870 GO:0034871 biolink:MolecularActivity 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-. UM-BBD_reactionID:r1308 go-plus.json http://purl.obolibrary.org/obo/GO_0034871 GO:0034872 biolink:MolecularActivity trans-geranyl-CoA isomerase activity Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA. EC:5.2.1.-|UM-BBD_reactionID:r1310 go-plus.json http://purl.obolibrary.org/obo/GO_0034872 GO:0034873 biolink:MolecularActivity thioacetamide S-oxygenase activity Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O. UM-BBD_reactionID:r1312 go-plus.json http://purl.obolibrary.org/obo/GO_0034873 GO:0034874 biolink:MolecularActivity thioacetamide S-oxide S-oxygenase activity Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O. UM-BBD_reactionID:r1313 go-plus.json http://purl.obolibrary.org/obo/GO_0034874 GO:0034875 biolink:MolecularActivity caffeine oxidase activity Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O. EC:1.17.5.2|RHEA:47148|UM-BBD_reactionID:r1321 go-plus.json http://purl.obolibrary.org/obo/GO_0034875 GO:0019238 biolink:MolecularActivity cyclohydrolase activity Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring. go-plus.json http://purl.obolibrary.org/obo/GO_0019238 GO:0034876 biolink:MolecularActivity isonicotinic acid hydrazide hydrolase activity Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine. UM-BBD_reactionID:r1336 go-plus.json http://purl.obolibrary.org/obo/GO_0034876 GO:0019239 biolink:MolecularActivity deaminase activity Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH3/NH2R). Reactome:R-HSA-9014641 go-plus.json http://purl.obolibrary.org/obo/GO_0019239 goslim_pir GO:0019236 biolink:BiologicalProcess response to pheromone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. go-plus.json pheromone response http://purl.obolibrary.org/obo/GO_0019236 GO:0019237 biolink:MolecularActivity centromeric DNA binding Binding to a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis. go-plus.json centromere binding http://purl.obolibrary.org/obo/GO_0019237 GO:0019234 biolink:BiologicalProcess sensory perception of fast pain The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds. go-plus.json http://purl.obolibrary.org/obo/GO_0019234 GO:0019235 biolink:BiologicalProcess sensory perception of slow pain The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction. go-plus.json http://purl.obolibrary.org/obo/GO_0019235 CHEBI:33094 biolink:ChemicalSubstance (S)-3-aminoisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_33094 GO:0019232 biolink:BiologicalProcess perception of rate of movement The series of events by which an organism senses the speed and direction of movement of the body and its parts. go-plus.json kinesthesia http://purl.obolibrary.org/obo/GO_0019232 GO:0019233 biolink:BiologicalProcess sensory perception of pain The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. Wikipedia:Nociception go-plus.json nociception|perception of physiological pain http://purl.obolibrary.org/obo/GO_0019233 GO:0019230 biolink:BiologicalProcess proprioception The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. Wikipedia:Proprioception go-plus.json http://purl.obolibrary.org/obo/GO_0019230 GO:0019231 biolink:BiologicalProcess perception of static position The perception of the orientation of different parts of the body with respect to one another. go-plus.json http://purl.obolibrary.org/obo/GO_0019231 CHEBI:72662 biolink:ChemicalSubstance DiHOME go-plus.json http://purl.obolibrary.org/obo/CHEBI_72662 CHEBI:72674 biolink:ChemicalSubstance versicolorin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_72674 GO:0019250 biolink:BiologicalProcess aerobic cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen. MetaCyc:P381-PWY go-plus.json cobalamin biosynthesis, aerobic|cobalamin biosynthetic process, aerobic|aerobic cobalamin anabolism|aerobic cobalamin synthesis|aerobic cobalamin biosynthesis|aerobic cobalamin formation|aerobic vitamin B12 biosynthetic process|aerobic vitamin B12 biosynthesis|vitamin B12 biosynthetic process, aerobic|vitamin B12 biosynthesis, aerobic http://purl.obolibrary.org/obo/GO_0019250 GO:0019251 biolink:BiologicalProcess anaerobic cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen. MetaCyc:COBALSYN-PWY go-plus.json anaerobic cobalamin biosynthesis|anaerobic vitamin B12 biosynthetic process|anaerobic vitamin B12 biosynthesis|vitamin B12 biosynthetic process, anaerobic|vitamin B12 biosynthesis, anaerobic|cobalamin biosynthesis, anaerobic|cobalamin biosynthetic process, anaerobic|anaerobic cobalamin anabolism|anaerobic cobalamin synthesis|anaerobic cobalamin formation http://purl.obolibrary.org/obo/GO_0019251 CHEBI:72676 biolink:ChemicalSubstance versicolorin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_72676 CHEBI:72677 biolink:ChemicalSubstance dihydrosterigmatocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72677 chebi_ph7_3 CHEBI:72678 biolink:ChemicalSubstance 8-O-methyldihydrosterigmatocystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72678 chebi_ph7_3 GO:0034866 biolink:MolecularActivity 2,4,4-trimethylpentanoyl-CoA dehydrogenase activity Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r1276 go-plus.json http://purl.obolibrary.org/obo/GO_0034866 GO:0034867 biolink:MolecularActivity 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA. UM-BBD_reactionID:r1277 go-plus.json http://purl.obolibrary.org/obo/GO_0034867 GO:0034868 biolink:MolecularActivity 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r1273 go-plus.json http://purl.obolibrary.org/obo/GO_0034868 GO:0034869 biolink:MolecularActivity 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH. UM-BBD_reactionID:r1307 go-plus.json http://purl.obolibrary.org/obo/GO_0034869 GO:0034860 biolink:MolecularActivity 2-mercaptobenzothiazole desulfurase activity Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor. UM-BBD_reactionID:r1288|EC:4.4.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034860 GO:0034861 biolink:MolecularActivity benzothiazole-2-sulfonate hydrolase activity Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-. EC:3.13.1.-|UM-BBD_reactionID:r1290 go-plus.json http://purl.obolibrary.org/obo/GO_0034861 GO:0034862 biolink:MolecularActivity 2,6-dihydroxybenzothiazole monooxygenase activity Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole. UM-BBD_reactionID:r1294 go-plus.json http://purl.obolibrary.org/obo/GO_0034862 GO:0034863 biolink:MolecularActivity 2,4,4-trimethyl-1-pentanol dehydrogenase activity Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-. UM-BBD_reactionID:r1270 go-plus.json http://purl.obolibrary.org/obo/GO_0034863 CHEBI:139107 biolink:ChemicalSubstance (9S,13S)-1a,1b-dinor-12-oxo-10,15-phytodienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139107 CHEBI:139108 biolink:ChemicalSubstance hexadecanoyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139108 GO:0019249 biolink:BiologicalProcess lactate biosynthetic process The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid. go-plus.json lactate anabolism|lactate biosynthesis|lactate synthesis|lactate formation http://purl.obolibrary.org/obo/GO_0019249 GO:0034864 biolink:MolecularActivity 2,4,4-trimethylpentanal dehydrogenase activity Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-. UM-BBD_reactionID:r1275 go-plus.json http://purl.obolibrary.org/obo/GO_0034864 GO:0034865 biolink:MolecularActivity 2,4,4-trimethylpentanoate-CoA ligase activity Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-. UM-BBD_reactionID:r1271 go-plus.json http://purl.obolibrary.org/obo/GO_0034865 GO:0019247 biolink:BiologicalProcess lactate racemization Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture. go-plus.json http://purl.obolibrary.org/obo/GO_0019247 GO:0019248 biolink:BiologicalProcess D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde. MetaCyc:MGLDLCTANA-PWY go-plus.json D-lactate formation from methylglyoxal via (R)-lactaldehyde|D-lactate anabolism from methylglyoxal via (R)-lactaldehyde|D-lactate synthesis from methylglyoxal via (R)-lactaldehyde http://purl.obolibrary.org/obo/GO_0019248 GO:0019245 biolink:BiologicalProcess D(-)-lactate biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate. go-plus.json D(-)-lactate anabolism from pyruvate|D(-)-lactate synthesis from pyruvate|D(-)-lactate formation from pyruvate http://purl.obolibrary.org/obo/GO_0019245 CHEBI:139104 biolink:ChemicalSubstance (R,R)-3-(3-hydroxydecanoyloxy)decanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139104 chebi_ph7_3 GO:0019246 biolink:BiologicalProcess L(+)-lactate biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate. MetaCyc:PWY-5481 go-plus.json S-lactate biosynthetic process from pyruvate|L(+)-lactate anabolism from pyruvate|L(+)-lactate synthesis from pyruvate|L(+)-lactate formation from pyruvate http://purl.obolibrary.org/obo/GO_0019246 CHEBI:139105 biolink:ChemicalSubstance (9S,13S)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139105 GO:0019243 biolink:BiologicalProcess methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step. MetaCyc:PWY-5386 go-plus.json D-lactate biosynthetic process from methylglyoxal|D-lactate biosynthesis from methylglyoxal|glyoxalase system|methylglyoxal detoxification|methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione|methylglyoxal breakdown to D-lactate|methylglyoxal degradation to D-lactate http://purl.obolibrary.org/obo/GO_0019243 CHEBI:72670 biolink:ChemicalSubstance (2S)-versicolorone(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72670 GO:0019244 biolink:BiologicalProcess lactate biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate. Reactome:R-HSA-71849.1 go-plus.json lactate anabolism from pyruvate|lactate synthesis from pyruvate|lactate formation from pyruvate|pyruvate fermentation to lactate http://purl.obolibrary.org/obo/GO_0019244 CHEBI:72671 biolink:ChemicalSubstance (2S,3S)-versiconal hemiacetal acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_72671 GO:0019241 biolink:BiologicalProcess citrulline catabolic process The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. MetaCyc:CITRULLINE-DEG-PWY go-plus.json citrulline catabolism|citrulline degradation|citrulline breakdown http://purl.obolibrary.org/obo/GO_0019241 CHEBI:72672 biolink:ChemicalSubstance (2S-3S)-versiconal hemiacetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_72672 GO:0019242 biolink:BiologicalProcess methylglyoxal biosynthetic process The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. go-plus.json methylglyoxal anabolism|methylglyoxal synthesis|methylglyoxal formation|methylglyoxal biosynthesis http://purl.obolibrary.org/obo/GO_0019242 CHEBI:72673 biolink:ChemicalSubstance (3S)-versiconol acetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72673 chebi_ph7_3 CHEBI:140195 biolink:ChemicalSubstance 21-phosphorifampicin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140195 chebi_ph7_3 CHEBI:139197 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 24:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139197 chebi_ph7_3 CHEBI:139198 biolink:ChemicalSubstance hydroxy fatty acid anion 24:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139198 CHEBI:139199 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 26:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139199 chebi_ph7_3 CHEBI:140182 biolink:ChemicalSubstance hydroxyalbendazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_140182 chebi_ph7_3 CHEBI:140183 biolink:ChemicalSubstance (3R)-2'-hydroxyisoflavanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_140183 chebi_ph7_3 CHEBI:140181 biolink:ChemicalSubstance (3R,4R)-4,2'-dihydroxyisoflavans go-plus.json http://purl.obolibrary.org/obo/CHEBI_140181 chebi_ph7_3 CHEBI:140188 biolink:ChemicalSubstance 2alpha-hydroxy-ent-isokaurene go-plus.json http://purl.obolibrary.org/obo/CHEBI_140188 chebi_ph7_3 CHEBI:140189 biolink:ChemicalSubstance omega-hydroxy-beta-dihydromenaquinone-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_140189 chebi_ph7_3 CHEBI:140184 biolink:ChemicalSubstance hydroxyfenbendazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_140184 chebi_ph7_3 CHEBI:139182 biolink:ChemicalSubstance 4-(beta-D-glucopyranuronosyloxy)retinoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139182 chebi_ph7_3 CHEBI:139183 biolink:ChemicalSubstance 5,6-epoxyretinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139183 chebi_ph7_3 CHEBI:139184 biolink:ChemicalSubstance 1-O-(5,6-epoxyretinoyl)-beta-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139184 chebi_ph7_3 CHEBI:140170 biolink:ChemicalSubstance N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140170 chebi_ph7_3 CHEBI:139185 biolink:ChemicalSubstance 1-O-(4-oxoretinoyl)-beta-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139185 chebi_ph7_3 CHEBI:139181 biolink:ChemicalSubstance 1-O-(all-trans-retinoyl)-beta-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139181 chebi_ph7_3 CHEBI:140179 biolink:ChemicalSubstance 3'-L-prolyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140179 chebi_ph7_3 CHEBI:139179 biolink:ChemicalSubstance 4,4'-diapolycopen-4-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139179 GO:0019199 biolink:MolecularActivity transmembrane receptor protein kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. Reactome:R-HSA-8983059|Reactome:R-HSA-8983063 go-plus.json http://purl.obolibrary.org/obo/GO_0019199 GO:0019197 biolink:CellularComponent phosphoenolpyruvate-dependent sugar phosphotransferase complex Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system). go-plus.json http://purl.obolibrary.org/obo/GO_0019197 GO:0019198 biolink:MolecularActivity transmembrane receptor protein phosphatase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0019198 CHEBI:139193 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 20:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139193 chebi_ph7_3 CHEBI:139194 biolink:ChemicalSubstance hydroxy fatty acid anion 20:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139194 CHEBI:140161 biolink:ChemicalSubstance phosphatidylcholine (20:4/16:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140161 chebi_ph7_3 CHEBI:139195 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 22:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139195 chebi_ph7_3 CHEBI:139196 biolink:ChemicalSubstance hydroxy fatty acid anion 22:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139196 CHEBI:139190 biolink:ChemicalSubstance hydroxy fatty acid anion 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139190 CHEBI:139191 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139191 chebi_ph7_3 CHEBI:139192 biolink:ChemicalSubstance hydroxy fatty acid anion 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139192 CHEBI:140168 biolink:ChemicalSubstance N(4)-{alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140168 chebi_ph7_3 CHEBI:140169 biolink:ChemicalSubstance N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140169 chebi_ph7_3 CHEBI:140165 biolink:ChemicalSubstance Brassica napus metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_140165 OBA:1001065 biolink:OntologyClass cell morphology The morphology of a cell. go-plus.json morphology of cell http://purl.obolibrary.org/obo/OBA_1001065 CHEBI:139186 biolink:ChemicalSubstance retinoid glucosiduronic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139186 CHEBI:139187 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139187 chebi_ph7_3 CHEBI:139188 biolink:ChemicalSubstance hydroxy fatty acid anion 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139188 CHEBI:139189 biolink:ChemicalSubstance 2-hydroxy fatty acid anion 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139189 chebi_ph7_3 GO:0044140 biolink:BiologicalProcess obsolete negative regulation of growth of symbiont on or near host surface OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044140 GO:0010808 biolink:BiologicalProcess positive regulation of synaptic vesicle priming Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0010808 GO:0009819 biolink:BiologicalProcess drought recovery Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition. go-plus.json drought tolerance http://purl.obolibrary.org/obo/GO_0009819 GO:0044141 biolink:BiologicalProcess obsolete negative regulation of development of symbiont on or near host surface OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044141 GO:0010809 biolink:BiologicalProcess negative regulation of synaptic vesicle priming Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0010809 GO:0010806 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010806 CHEBI:23673 biolink:ChemicalSubstance 2,6-diaminopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23673 GO:0010807 biolink:BiologicalProcess regulation of synaptic vesicle priming Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0010807 goslim_synapse CHEBI:23677 biolink:ChemicalSubstance diazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_23677 GO:0044148 biolink:BiologicalProcess obsolete positive regulation of growth of symbiont involved in interaction with host OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism. go-plus.json positive regulation of growth of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0044148 GO:0010800 biolink:BiologicalProcess positive regulation of peptidyl-threonine phosphorylation Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0010800 GO:0044149 biolink:BiologicalProcess positive regulation of formation of structure involved in a symbiotic process Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. go-plus.json positive regulation of development of symbiont during interaction with host|positive regulation of development of symbiont involved in interaction with host http://purl.obolibrary.org/obo/GO_0044149 GO:0010801 biolink:BiologicalProcess negative regulation of peptidyl-threonine phosphorylation Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0010801 GO:0044146 biolink:BiologicalProcess obsolete negative regulation of growth of symbiont involved in interaction with host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism. go-plus.json negative regulation of growth of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0044146 GO:0044147 biolink:BiologicalProcess negative regulation of formation of structure involved in a symbiotic process Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. go-plus.json negative regulation of development of symbiont involved in interaction with host|negative regulation of development of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0044147 GO:0010804 biolink:BiologicalProcess negative regulation of tumor necrosis factor-mediated signaling pathway Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. go-plus.json negative regulation of TNF-mediated signaling pathway|negative regulation of tumor necrosis factor-mediated signalling pathway|negative regulation of TNF signaling http://purl.obolibrary.org/obo/GO_0010804 GO:0044144 biolink:BiologicalProcess obsolete modulation of growth of symbiont involved in interaction with host OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism. go-plus.json modulation of growth of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0044144 GO:0044145 biolink:BiologicalProcess modulation of formation of structure involved in a symbiotic process Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. go-plus.json modulation of development of symbiont involved in interaction with host|modulation of development of symbiont during interaction with host http://purl.obolibrary.org/obo/GO_0044145 GO:0010805 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010805 CHEBI:23671 biolink:ChemicalSubstance 2,6-diaminopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_23671 GO:0044142 biolink:BiologicalProcess obsolete positive regulation of growth of symbiont on or near host surface OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass on or near the cells or tissues of the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044142 GO:0010802 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010802 GO:0044143 biolink:BiologicalProcess obsolete positive regulation of development of symbiont on or near host surface OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044143 GO:0010803 biolink:BiologicalProcess regulation of tumor necrosis factor-mediated signaling pathway Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. go-plus.json regulation of tumor necrosis factor-mediated signalling pathway|regulation of TNF signaling|regulation of TNF-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0010803 GO:0009810 biolink:BiologicalProcess stilbene metabolic process The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA. go-plus.json stilbene metabolism http://purl.obolibrary.org/obo/GO_0009810 GO:0009811 biolink:BiologicalProcess stilbene biosynthetic process The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA. go-plus.json stilbene synthesis|stilbene formation|stilbene biosynthesis|stilbene anabolism http://purl.obolibrary.org/obo/GO_0009811 UBERON:0004668 biolink:AnatomicalEntity fourth ventricle aperture One of: the 4th ventricle median or lateral apertures. go-plus.json aperture of fourth ventricle|aperture of 4th ventricle http://purl.obolibrary.org/obo/UBERON_0004668 GO:0009812 biolink:BiologicalProcess flavonoid metabolic process The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins. go-plus.json flavonoid metabolism http://purl.obolibrary.org/obo/GO_0009812 UBERON:0004666 biolink:AnatomicalEntity interventricular septum membranous part The membranous portion of the wall between the two lower chambers of the heart go-plus.json membranous part of interventricular septum|membranous septum|ventricular membranous septum|membranous interventricular septum|pars membranacea (septi interventricularis)|membranous part interventricular septum|membranous interventricular septum|membranous portion of interventricular septum|ventricle membranous septum|pars membranacea septi interventricularis|cardiac ventricular membranous septum http://purl.obolibrary.org/obo/UBERON_0004666 GO:0009813 biolink:BiologicalProcess flavonoid biosynthetic process The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton. Wikipedia:Flavonoid|MetaCyc:PWY1F-FLAVSYN go-plus.json flavonoid anabolism|flavonoid synthesis|flavonoid formation|flavonoid biosynthesis http://purl.obolibrary.org/obo/GO_0009813 UBERON:0004667 biolink:AnatomicalEntity interventricular septum muscular part The muscular portion of the wall between the two lower chambers of the heart go-plus.json cardiac ventricular muscular septum|muscular interventricular septum|muscular septum|pars muscularis septi interventricularis|muscular part interventricular septum|septum membranaceum|pars muscularis (septi interventricularis)|muscular part of interventricular septum|ventricular muscular septum|muscular interventricular septum http://purl.obolibrary.org/obo/UBERON_0004667 GO:0009814 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009814 UBERON:0004664 biolink:AnatomicalEntity aorta tunica adventitia the outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers go-plus.json tunica adventitia of aorta http://purl.obolibrary.org/obo/UBERON_0004664 GO:0009815 biolink:MolecularActivity 1-aminocyclopropane-1-carboxylate oxidase activity Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene. RHEA:23640|KEGG_REACTION:R07214|EC:1.14.17.4|MetaCyc:ETHYL-RXN go-plus.json ethylene-forming enzyme|aminocyclopropanecarboxylate oxidase activity|ethene-forming enzyme|ACC oxidase activity|1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming) http://purl.obolibrary.org/obo/GO_0009815 UBERON:0004665 biolink:AnatomicalEntity muscular coat of seminal vesicle A muscular coat that is part of a seminal vesicle [Automatically generated definition]. go-plus.json muscular layer of seminal gland|tunica muscularis glandulae vesiculosae|muscle layer of seminal vesicle|muscular coat of seminal gland|tunica muscularis (vesicula seminalis) http://purl.obolibrary.org/obo/UBERON_0004665 GO:0009816 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009816 GO:0009817 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009817 UBERON:0004663 biolink:AnatomicalEntity aorta wall An anatomical wall that is part of an aorta, enclosing the luminal space. go-plus.json aortic wall|wall of aorta http://purl.obolibrary.org/obo/UBERON_0004663 GO:0009818 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009818 GO:0044151 biolink:BiologicalProcess obsolete growth of host on or near symbiont surface OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json growth of organism on or near symbiont surface http://purl.obolibrary.org/obo/GO_0044151 GO:0010819 biolink:BiologicalProcess regulation of T cell chemotaxis Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010819 GO:0044152 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044152 GO:0010817 biolink:BiologicalProcess regulation of hormone levels Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. go-plus.json http://purl.obolibrary.org/obo/GO_0010817 CHEBI:23683 biolink:ChemicalSubstance dibenzothiophene 5-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23683 chebi_ph7_3 GO:0010818 biolink:BiologicalProcess T cell chemotaxis The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. go-plus.json T-cell chemotaxis http://purl.obolibrary.org/obo/GO_0010818 GO:0044150 biolink:BiologicalProcess obsolete development of host on or near symbiont surface OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json development of organism on or near symbiont surface http://purl.obolibrary.org/obo/GO_0044150 CHEBI:23684 biolink:ChemicalSubstance dibenzothiophenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_23684 UBERON:0004649 biolink:AnatomicalEntity sphenoid bone pterygoid process the process projecting downward from either side of the sphenoid bone, in vertebrates divided into two plates, an inner and an outer (sometimes called the lateral and medial); the posterior nares pass through the space, called the pterygoid fossa, between the processes go-plus.json processus pterygoideus|pterygoid process of sphenoid bone|processus pterygoideus ossis sphenoidalis|pterygoid process of sphenoid bone|pterygoid processes|processus pterygoideus ossis sphenoidalis|pterygoid plate|pterygoid process|pterygoid process of sphenoid|pterygoid process|pterygoid processus http://purl.obolibrary.org/obo/UBERON_0004649 GO:0044159 biolink:CellularComponent host thylakoid A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. go-plus.json http://purl.obolibrary.org/obo/GO_0044159 GO:0010811 biolink:BiologicalProcess positive regulation of cell-substrate adhesion Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0010811 GO:0010812 biolink:BiologicalProcess negative regulation of cell-substrate adhesion Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0010812 GO:0044157 biolink:CellularComponent host cell projection A prolongation or process extending from a host cell, e.g. a flagellum or axon. go-plus.json http://purl.obolibrary.org/obo/GO_0044157 GO:0010810 biolink:BiologicalProcess regulation of cell-substrate adhesion Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0010810 GO:0044158 biolink:CellularComponent host cell wall The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0044158 GO:0044155 biolink:CellularComponent host caveola A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0044155 CHEBI:23681 biolink:ChemicalSubstance dibenzothiophene go-plus.json http://purl.obolibrary.org/obo/CHEBI_23681 chebi_ph7_3 GO:0010815 biolink:BiologicalProcess bradykinin catabolic process The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin. go-plus.json http://purl.obolibrary.org/obo/GO_0010815 GO:0010816 biolink:BiologicalProcess calcitonin catabolic process The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin. go-plus.json http://purl.obolibrary.org/obo/GO_0010816 GO:0044156 biolink:CellularComponent host cell junction A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0044156 GO:0010813 biolink:BiologicalProcess neuropeptide catabolic process The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction. go-plus.json http://purl.obolibrary.org/obo/GO_0010813 GO:0044153 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044153 GO:0044154 biolink:BiologicalProcess histone H3-K14 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone. go-plus.json histone H3K14 acetylation|histone H3 acetylation at K14 http://purl.obolibrary.org/obo/GO_0044154 GO:0010814 biolink:BiologicalProcess substance P catabolic process The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P. go-plus.json http://purl.obolibrary.org/obo/GO_0010814 UBERON:0004650 biolink:AnatomicalEntity tongue keratinized epithelium A keratinized stratified squamous epithelium that is part of a tongue. go-plus.json keratinized epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0004650 GO:0009820 biolink:BiologicalProcess alkaloid metabolic process The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). go-plus.json alkaloid metabolism http://purl.obolibrary.org/obo/GO_0009820 goslim_chembl GO:0009821 biolink:BiologicalProcess alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases). UM-BBD_enzymeID:e0711 go-plus.json alkaloid anabolism|alkaloid synthesis|alkaloid formation|alkaloid biosynthesis http://purl.obolibrary.org/obo/GO_0009821 CHEBI:33007 biolink:ChemicalSubstance chromium(6+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_33007 chebi_ph7_3 GO:0009822 biolink:BiologicalProcess alkaloid catabolic process The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). go-plus.json alkaloid breakdown|alkaloid catabolism|alkaloid degradation http://purl.obolibrary.org/obo/GO_0009822 GO:0009823 biolink:BiologicalProcess cytokinin catabolic process The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators. go-plus.json cytokinin catabolism|cytokinin degradation|cytokinin breakdown http://purl.obolibrary.org/obo/GO_0009823 GO:0009824 biolink:MolecularActivity AMP dimethylallyltransferase activity Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate. MetaCyc:RXN-4307|EC:2.5.1.27|KEGG_REACTION:R04038|RHEA:15285 go-plus.json 2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity|2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity|isopentenyltransferase activity|cytokinin synthase activity|dimethylallyl-diphosphate:AMP dimethylallyltransferase activity|adenylate isopentenyltransferase activity|adenylate dimethylallyltransferase activity http://purl.obolibrary.org/obo/GO_0009824 GO:0009825 biolink:BiologicalProcess multidimensional cell growth The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes. go-plus.json cell growth in three dimensions|cell growth in two dimensions http://purl.obolibrary.org/obo/GO_0009825 GO:0009826 biolink:BiologicalProcess unidimensional cell growth The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell. go-plus.json polar cell growth|cell growth along one axis|cell elongation|polarized cell growth|cell growth in one dimension|cell morphogenesis by unidimensional growth http://purl.obolibrary.org/obo/GO_0009826 GO:0009827 biolink:BiologicalProcess plant-type cell wall modification The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana. go-plus.json cellulose and pectin-containing cell wall modification http://purl.obolibrary.org/obo/GO_0009827 GO:0009828 biolink:BiologicalProcess plant-type cell wall loosening The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana. go-plus.json cellulose and pectin-containing cell wall loosening http://purl.obolibrary.org/obo/GO_0009828 UBERON:0004652 biolink:AnatomicalEntity humerus diaphysis The body or shaft of the humerus is almost cylindrical in the upper half of its extent, prismatic and flattened below, and has three borders and three surfaces. go-plus.json shaft of the humerus|corpus humeri|humeral diaphysis|medial humerus|body of the humerus|diaphysis of humerus|shaft of humerus|body of humerus http://purl.obolibrary.org/obo/UBERON_0004652 GO:0009829 biolink:BiologicalProcess cell wall modification involved in fruit ripening The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening. go-plus.json cell wall modification during ripening http://purl.obolibrary.org/obo/GO_0009829 GO:0044162 biolink:CellularComponent host cell cytoplasmic vesicle membrane The lipid bilayer surrounding a host cell cytoplasmic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0044162 CHEBI:23652 biolink:ChemicalSubstance dextrins go-plus.json http://purl.obolibrary.org/obo/CHEBI_23652 GO:0044163 biolink:CellularComponent host cytoskeleton Any of the various filamentous elements that form the internal framework of host cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the host cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the host cell. The various elements of the host cytoskeleton not only serve in the maintenance of host cellular shape but also have roles in other host cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. go-plus.json http://purl.obolibrary.org/obo/GO_0044163 GO:0044160 biolink:CellularComponent host thylakoid membrane The pigmented membrane of any host thylakoid. go-plus.json http://purl.obolibrary.org/obo/GO_0044160 GO:0044161 biolink:CellularComponent host cell cytoplasmic vesicle A vesicle formed of membrane or protein, found in the cytoplasm of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0044161 CHEBI:47622 biolink:ChemicalSubstance acetate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_47622 chebi_ph7_3 UBERON:0004637 biolink:AnatomicalEntity otic capsule The capsule surrounding the inner ear mechanism. go-plus.json otic capsule skeletal element|periotic capsule|otic region|otic capsule|otic capsule element|periotic|auditory capsule|otic capsule endochondral element http://purl.obolibrary.org/obo/UBERON_0004637 UBERON:0004638 biolink:AnatomicalEntity blood vessel endothelium An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart go-plus.json http://purl.obolibrary.org/obo/UBERON_0004638 GO:0044168 biolink:CellularComponent host cell rough endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface. go-plus.json host rough endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0044168 GO:0044169 biolink:CellularComponent host cell rough endoplasmic reticulum membrane The lipid bilayer surrounding the host cell rough endoplasmic reticulum. go-plus.json host rough endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0044169 GO:0044166 biolink:CellularComponent host cell endoplasmic reticulum lumen The volume enclosed by the membranes of the host cell endoplasmic reticulum. go-plus.json host endoplasmic reticulum lumen http://purl.obolibrary.org/obo/GO_0044166 GO:0044167 biolink:CellularComponent host cell endoplasmic reticulum membrane The lipid bilayer surrounding the host cell endoplasmic reticulum. go-plus.json host endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0044167 GO:0044164 biolink:CellularComponent host cell cytosol The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. go-plus.json host cytosol http://purl.obolibrary.org/obo/GO_0044164 GO:0044165 biolink:CellularComponent host cell endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). go-plus.json host endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0044165 UBERON:0004647 biolink:AnatomicalEntity liver lobule the polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein go-plus.json lobuli hepatis|lobuli hepatici|lobules of liver|lobulus hepaticus|hepatic lobule http://purl.obolibrary.org/obo/UBERON_0004647 UBERON:0004645 biolink:AnatomicalEntity urinary bladder urothelium The epithelial lining of the luminal space of the urinary bladder. go-plus.json urothelium of urinary bladder|urothelium|transitional epithelium|bladder transitional cell epithelium|transitional epithelium of urinary bladder|urinary bladder transitional epithelium|epithelium of bladder http://purl.obolibrary.org/obo/UBERON_0004645 UBERON:0004641 biolink:AnatomicalEntity spleen capsule the connective tissue that surrounds the spleen go-plus.json tunica fibrosa splenica|capsula splenica|splenic capsule|tunica fibrosa (splen)(lien)|capsule of spleen|Malpighian capsule|fibrous capsule of spleen|fibroelastic coat of spleen http://purl.obolibrary.org/obo/UBERON_0004641 GO:0044173 biolink:CellularComponent host cell endoplasmic reticulum-Golgi intermediate compartment membrane The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system. go-plus.json host endoplasmic reticulum-Golgi intermediate compartment membrane|host cell ER-Golgi intermediate compartment membrane|host ER-Golgi intermediate compartment membrane http://purl.obolibrary.org/obo/GO_0044173 GO:0009808 biolink:BiologicalProcess lignin metabolic process The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units. go-plus.json lignin metabolism http://purl.obolibrary.org/obo/GO_0009808 GO:0009809 biolink:BiologicalProcess lignin biosynthetic process The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers. MetaCyc:PWY-361 go-plus.json lignin biosynthesis|lignin anabolism|lignin synthesis|lignin formation http://purl.obolibrary.org/obo/GO_0009809 GO:0044174 biolink:CellularComponent host cell endosome A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation. go-plus.json host endosome http://purl.obolibrary.org/obo/GO_0044174 GO:0044171 biolink:CellularComponent host cell smooth endoplasmic reticulum membrane The lipid bilayer surrounding the host cell smooth endoplasmic reticulum. go-plus.json host smooth endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0044171 GO:0044172 biolink:CellularComponent host cell endoplasmic reticulum-Golgi intermediate compartment A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport. go-plus.json host ER-Golgi intermediate compartment|host cell ER-Golgi intermediate compartment http://purl.obolibrary.org/obo/GO_0044172 GO:0044170 biolink:CellularComponent host cell smooth endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface. go-plus.json host smooth endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0044170 CHEBI:23666 biolink:ChemicalSubstance diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_23666 GO:0044179 biolink:BiologicalProcess hemolysis in other organism The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another. go-plus.json hemolysis of red blood cells in other organism|hemolysis of RBCs in other organism|hemolysis of erythrocytes in other organism|hemolysis of cells in other organism http://purl.obolibrary.org/obo/GO_0044179 goslim_chembl GO:0044177 biolink:CellularComponent host cell Golgi apparatus A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. go-plus.json host Golgi apparatus http://purl.obolibrary.org/obo/GO_0044177 GO:0044178 biolink:CellularComponent host cell Golgi membrane The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus. go-plus.json host Golgi membrane http://purl.obolibrary.org/obo/GO_0044178 GO:0044175 biolink:CellularComponent host cell endosome membrane The lipid bilayer surrounding a host cell endosome. go-plus.json host endosome membrane http://purl.obolibrary.org/obo/GO_0044175 GO:0044176 biolink:CellularComponent host cell filopodium Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. go-plus.json host filopodium http://purl.obolibrary.org/obo/GO_0044176 CHEBI:1233 biolink:ChemicalSubstance 3-(all-trans-octaprenyl)benzene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1233 chebi_ph7_3 CHEBI:1235 biolink:ChemicalSubstance 2-methoxy-6-(all-trans-octaprenyl)phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1235 chebi_ph7_3 GO:0009800 biolink:BiologicalProcess cinnamic acid biosynthetic process The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid. go-plus.json cinnamic acid synthesis|cinnamic acid formation|cinnamic acid biosynthesis|phenylpropenoic acid biosynthetic process|phenylacrylic acid biosynthesis|phenylacrylic acid biosynthetic process|phenylpropenoic acid biosynthesis|cinnamylic acid biosynthetic process|cinnamylic acid biosynthesis|cinnamic acid anabolism http://purl.obolibrary.org/obo/GO_0009800 GO:0009801 biolink:BiologicalProcess cinnamic acid ester metabolic process The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid. go-plus.json cinnamic acid ester metabolism http://purl.obolibrary.org/obo/GO_0009801 GO:0009802 biolink:BiologicalProcess cinnamic acid ester biosynthetic process The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid. go-plus.json phenylacrylic acid ester biosynthesis|phenylacrylic acid ester biosynthetic process|cinnamic acid ester anabolism|cinnamylic acid ester biosynthetic process|cinnamylic acid ester biosynthesis|cinnamic acid ester synthesis|cinnamic acid ester formation|cinnamic acid ester biosynthesis http://purl.obolibrary.org/obo/GO_0009802 GO:0009803 biolink:BiologicalProcess cinnamic acid metabolic process The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid. go-plus.json cinnamylic acid metabolic process|cinnamic acid metabolism|phenylacrylic acid metabolic process|phenylpropenoic acid metabolic process|phenylacrylic acid metabolism|phenylpropenoic acid metabolism|cinnamylic acid metabolism http://purl.obolibrary.org/obo/GO_0009803 GO:0009804 biolink:BiologicalProcess coumarin metabolic process The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids. go-plus.json coumarin metabolism http://purl.obolibrary.org/obo/GO_0009804 GO:0009805 biolink:BiologicalProcess coumarin biosynthetic process The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids. MetaCyc:PWY-5176 go-plus.json coumarin anabolism|coumarin biosynthesis|coumarin synthesis|coumarin formation http://purl.obolibrary.org/obo/GO_0009805 CHEBI:1230 biolink:ChemicalSubstance sophorose go-plus.json http://purl.obolibrary.org/obo/CHEBI_1230 chebi_ph7_3 GO:0009806 biolink:BiologicalProcess lignan metabolic process The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist. go-plus.json lignan metabolism http://purl.obolibrary.org/obo/GO_0009806 GO:0009807 biolink:BiologicalProcess lignan biosynthetic process The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist. go-plus.json lignan synthesis|lignan formation|lignan biosynthesis|lignan anabolism http://purl.obolibrary.org/obo/GO_0009807 GO:0044184 biolink:CellularComponent host cell late endosome A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. go-plus.json http://purl.obolibrary.org/obo/GO_0044184 CHEBI:23630 biolink:ChemicalSubstance deoxyinosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23630 GO:0044185 biolink:CellularComponent host cell late endosome membrane The lipid bilayer surrounding a host cell late endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0044185 GO:0044182 biolink:BiologicalProcess filamentous growth of a population of unicellular organisms The process in which a group of unicellular organisms grow in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0044182 GO:0044183 biolink:MolecularActivity protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process. Reactome:R-HSA-9018785 go-plus.json protein binding involved in protein folding|chaperone activity http://purl.obolibrary.org/obo/GO_0044183 goslim_chembl CHEBI:47600 biolink:ChemicalSubstance purvalanol A go-plus.json http://purl.obolibrary.org/obo/CHEBI_47600 chebi_ph7_3 GO:0044180 biolink:BiologicalProcess filamentous growth of a unicellular organism The process in which a unicellular organism grows in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0044180 CHEBI:23634 biolink:ChemicalSubstance deoxyaldopentose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23634 CHEBI:23635 biolink:ChemicalSubstance deoxypentose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23635 GO:0044181 biolink:BiologicalProcess filamentous growth of a multicellular organism The process in which a multicellular organism grows in a threadlike, filamentous shape. go-plus.json http://purl.obolibrary.org/obo/GO_0044181 GO:0044188 biolink:CellularComponent host cell lysosomal membrane The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0044188 GO:0044189 biolink:CellularComponent obsolete host cell microsome OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic host cells are homogenized and that sediment on centrifugation at 100000 g. go-plus.json host cell microsomal membrane|host cell microsome http://purl.obolibrary.org/obo/GO_0044189 GO:0044186 biolink:CellularComponent host cell lipid droplet Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins. go-plus.json host cell lipid adiposome|host cell lipid particle|host cell lipid body http://purl.obolibrary.org/obo/GO_0044186 GO:0044187 biolink:CellularComponent host cell lysosome A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions. go-plus.json http://purl.obolibrary.org/obo/GO_0044187 CHEBI:23638 biolink:ChemicalSubstance deoxyribulose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23638 CHEBI:23639 biolink:ChemicalSubstance deoxy sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_23639 CHEBI:23636 biolink:ChemicalSubstance deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_23636 GO:0044195 biolink:CellularComponent nucleoplasmic reticulum Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport. go-plus.json nuclear channels http://purl.obolibrary.org/obo/GO_0044195 CHEBI:23641 biolink:ChemicalSubstance deoxyuridine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23641 GO:0044196 biolink:CellularComponent host cell nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic host cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044196 GO:0044193 biolink:CellularComponent host cell mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0044193 GO:0044194 biolink:CellularComponent cytolytic granule A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044194 GO:0044191 biolink:CellularComponent host cell mitochondrial membrane Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0044191 GO:0044192 biolink:CellularComponent host cell mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae. go-plus.json http://purl.obolibrary.org/obo/GO_0044192 CHEBI:23643 biolink:ChemicalSubstance depsipeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_23643 GO:0044190 biolink:CellularComponent host cell mitochondrial envelope The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0044190 GO:0044199 biolink:CellularComponent host cell nuclear envelope The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). go-plus.json http://purl.obolibrary.org/obo/GO_0044199 GO:0044197 biolink:MolecularActivity Rel homology domain binding Binding to a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT. go-plus.json RHD binding http://purl.obolibrary.org/obo/GO_0044197 GO:0044198 biolink:MolecularActivity zf-TRAF domain binding Binding to a TRAF-type zinc finger domain of a protein. go-plus.json zinc-finger-TRAF domain binding|zinc finger TRAF-type domain binding|TRAF-type zinc finger domain binding http://purl.obolibrary.org/obo/GO_0044198 UBERON:0004693 biolink:AnatomicalEntity Peyer's patch epithelium the specialized epithelium of the Peyer's patch go-plus.json peyer's patch epithelium http://purl.obolibrary.org/obo/UBERON_0004693 UBERON:0004694 biolink:AnatomicalEntity Harderian gland epithelium An epithelium that is part of a Harderian gland [Automatically generated definition]. go-plus.json epithelium of harderian gland|harderian gland epithelium http://purl.obolibrary.org/obo/UBERON_0004694 UBERON:0004692 biolink:AnatomicalEntity external naris epithelium An epithelium that is part of an external naris [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004692 UBERON:0004699 biolink:AnatomicalEntity outflow tract endothelium An endothelium that is part of a outflow tract [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004699 UBERON:0004697 biolink:AnatomicalEntity Peyer's patch germinal center Area of the Peyer's patch where B cells proliferate and differentiate into plasma cells go-plus.json http://purl.obolibrary.org/obo/UBERON_0004697 CHEBI:1294 biolink:ChemicalSubstance (20R,22R)-20,22-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1294 chebi_ph7_3 UBERON:0004698 biolink:AnatomicalEntity vena cava endothelium An endothelium that is part of a vena cava [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004698 UBERON:0004695 biolink:AnatomicalEntity arterial system smooth muscle A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004695 UBERON:0004696 biolink:AnatomicalEntity venous system smooth muscle A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004696 CHEBI:23612 biolink:ChemicalSubstance deoxyadenosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23612 NCBITaxon:68459 biolink:OrganismalEntity Giardiinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_68459 UBERON:0004681 biolink:AnatomicalEntity vestibular system The sensory system for the sense of balance. go-plus.json vestibular system|vestibulomotor system|vestibular organ system|equilibrioception system http://purl.obolibrary.org/obo/UBERON_0004681 CHEBI:1269 biolink:ChemicalSubstance 2-polyprenylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1269 chebi_ph7_3 CHEBI:23614 biolink:ChemicalSubstance deoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23614 chebi_ph7_3 UBERON:0004688 biolink:AnatomicalEntity costo-cervical trunk The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]. go-plus.json costocervical trunk|truncus costocervicalis|trunk of costocervical artery http://purl.obolibrary.org/obo/UBERON_0004688 UBERON:0004684 biolink:AnatomicalEntity raphe nuclei The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. go-plus.json nuclei raphes|raphe of mesenchephalon|nuclei raphes|set of raphe nuclei|raphe nuclei set|raphe nuclei|raphe cluster|raphe nucleus http://purl.obolibrary.org/obo/UBERON_0004684 CHEBI:23618 biolink:ChemicalSubstance deoxycortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_23618 CHEBI:23623 biolink:ChemicalSubstance deoxyglucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23623 CHEBI:23621 biolink:ChemicalSubstance deoxycytidine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23621 CHEBI:23622 biolink:ChemicalSubstance deoxygalactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23622 CHEBI:23627 biolink:ChemicalSubstance deoxyaldohexose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23627 UBERON:0004679 biolink:AnatomicalEntity dentate gyrus molecular layer The molecular layer of the dentate gyrus that is bounded by the pial surface superficially and the dentate gyrus granule cell layer deep. It is divided into 2 or more sublayers. go-plus.json molecular layer of the dentate gyrus|dentate gyrus molecular layer|molecular layer of dentate gyrus|stratum moleculare gyri dentati http://purl.obolibrary.org/obo/UBERON_0004679 CHEBI:23628 biolink:ChemicalSubstance deoxyhexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_23628 CHEBI:23625 biolink:ChemicalSubstance deoxyguanosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23625 UBERON:0004675 biolink:AnatomicalEntity hypoglossal nerve root A nerve root that extends_fibers_into a hypoglossal nerve. go-plus.json hypoglossal nerve fibers|hypoglossal nerve root|fibrae nervi hypoglossi|central part of hypoglossal nerve|hypoglossal nerve fiber bundle|root of hypoglossal nerve|hypoglossal nerve tract|central part of hypoglossal nerve|root of hypoglossal nerve|hypoglossal nerve/ root|hypoglossal nerve fibers http://purl.obolibrary.org/obo/UBERON_0004675 UBERON:0004673 biolink:AnatomicalEntity trigeminal nerve root A nerve root that extends_fibers_into a trigeminal nerve. go-plus.json radix descendens nervi trigemini|root of trigeminal nerve|trigeminal nerve root|descending trigeminal root|root of trigeminal V nerve|trigeminal neural root http://purl.obolibrary.org/obo/UBERON_0004673 UBERON:0004674 biolink:AnatomicalEntity facial nerve root A nerve root that extends_fibers_into a facial nerve. go-plus.json facial nerve/root|facial nerve fibers|fibrae nervi facialis|facial neural root|facial nerve root|facial nerve or its root|root of facial nerve|central part of facial nerve http://purl.obolibrary.org/obo/UBERON_0004674 CHEBI:72564 biolink:ChemicalSubstance temozolomide go-plus.json http://purl.obolibrary.org/obo/CHEBI_72564 chebi_ph7_3 CHEBI:72565 biolink:ChemicalSubstance imidazotetrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_72565 GO:0034976 biolink:BiologicalProcess response to endoplasmic reticulum stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. go-plus.json cellular response to endoplasmic reticulum stress|response to ER stress|ER stress response http://purl.obolibrary.org/obo/GO_0034976 GO:0044302 biolink:CellularComponent dentate gyrus mossy fiber Distinctive, unmyelinated axons produced by granule cells. NIF_Subcellular:nlx_subcell_20090601 go-plus.json dentate gyrus mossy fibre|granule cell axon http://purl.obolibrary.org/obo/GO_0044302 GO:0044303 biolink:CellularComponent axon collateral Any of the smaller branches of an axon that emanate from the main axon cylinder. NIF_Subcellular:sao1470140754 go-plus.json http://purl.obolibrary.org/obo/GO_0044303 GO:0034977 biolink:CellularComponent ABIN2-NFKB1-MAP3K8 complex A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages. go-plus.json ABIN2-NFKB1-TPL-1 complex http://purl.obolibrary.org/obo/GO_0034977 GO:0044300 biolink:CellularComponent cerebellar mossy fiber An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations. NIF_Subcellular:nlx_subcell_20090209 go-plus.json cerebellar mossy fibre http://purl.obolibrary.org/obo/GO_0044300 GO:0034978 biolink:CellularComponent PDX1-PBX1b-MRG1 complex A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes. go-plus.json acinar cell-specific C complex http://purl.obolibrary.org/obo/GO_0034978 GO:0044301 biolink:CellularComponent climbing fiber The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber. NIF_Subcellular:nlx_subcell_20090203 go-plus.json climbing fibre http://purl.obolibrary.org/obo/GO_0044301 GO:0034979 biolink:MolecularActivity NAD-dependent protein deacetylase activity Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD. Reactome:R-HSA-5685953|Reactome:R-HSA-3371467|Reactome:R-HSA-9620532|Reactome:R-HSA-9667952|Reactome:R-HSA-5688289|Reactome:R-HSA-5688294|Reactome:R-HSA-5211239 go-plus.json http://purl.obolibrary.org/obo/GO_0034979 GO:0034970 biolink:BiologicalProcess histone H3-R2 methylation The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone. go-plus.json histone H3R2me|histone H3 R2 methylation|histone lysine H3 R2 methylation http://purl.obolibrary.org/obo/GO_0034970 GO:0044308 biolink:CellularComponent axonal spine A spine that originates from the axon, usually from the initial segment. NIF_Subcellular:sao18239917 go-plus.json axon spine http://purl.obolibrary.org/obo/GO_0044308 GO:0044309 biolink:CellularComponent neuron spine A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck. NIF_Subcellular:sao1145756102 go-plus.json spine http://purl.obolibrary.org/obo/GO_0044309 GO:0034971 biolink:BiologicalProcess histone H3-R17 methylation The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone. go-plus.json histone H3 R17 methylation|histone H3R17me|histone lysine H3 R17 methylation http://purl.obolibrary.org/obo/GO_0034971 GO:0034972 biolink:BiologicalProcess histone H3-R26 methylation The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone. go-plus.json histone lysine H3 R26 methylation|histone H3 R26 methylation|histone H3R26me http://purl.obolibrary.org/obo/GO_0034972 GO:0044306 biolink:CellularComponent neuron projection terminus The specialized, terminal region of a neuron projection such as an axon or a dendrite. go-plus.json neuron terminal specialization|neuron projection terminal|nerve terminal http://purl.obolibrary.org/obo/GO_0044306 GO:0019339 biolink:BiologicalProcess parathion catabolic process The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition. MetaCyc:PARATHION-DEGRADATION-PWY go-plus.json parathion catabolism|parathion degradation|parathion breakdown http://purl.obolibrary.org/obo/GO_0019339 GO:0044307 biolink:CellularComponent dendritic branch A dendrite arising from another dendrite. NIF_Subcellular:sao884265541 go-plus.json dendrite branch|secondary dendrite http://purl.obolibrary.org/obo/GO_0044307 GO:0034973 biolink:CellularComponent Sid2-Mob1 complex A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex. go-plus.json Sid2-Mob1 kinase complex|Sid2p-Mob1p complex|Dbf2p-Mob1p complex http://purl.obolibrary.org/obo/GO_0034973 GO:0044304 biolink:CellularComponent main axon The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites. NIF_Subcellular:sao1596975044 go-plus.json axon shaft|axonal shaft|axon trunk http://purl.obolibrary.org/obo/GO_0044304 GO:0019337 biolink:BiologicalProcess tetrachloroethylene catabolic process The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines. MetaCyc:PCEDEG-PWY go-plus.json tetrachloroethylene catabolism|tetrachloroethylene breakdown|tetrachloroethene catabolic process|tetrachloroethene catabolism|tetrachloroethylene degradation http://purl.obolibrary.org/obo/GO_0019337 GO:0034974 biolink:CellularComponent Swi5-Swi2 complex A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching. go-plus.json Swi5 complex http://purl.obolibrary.org/obo/GO_0034974 GO:0019338 biolink:BiologicalProcess pentachlorophenol catabolic process The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms. MetaCyc:PCPDEG-PWY go-plus.json pentachlorophenol breakdown|pentachlorophenol catabolism|pentachlorophenol degradation http://purl.obolibrary.org/obo/GO_0019338 GO:0034975 biolink:BiologicalProcess protein folding in endoplasmic reticulum A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). go-plus.json oxidative protein folding|protein folding in ER http://purl.obolibrary.org/obo/GO_0034975 GO:0044305 biolink:CellularComponent calyx of Held The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system. NIF_Subcellular:sao1684283879 go-plus.json http://purl.obolibrary.org/obo/GO_0044305 GO:0019335 biolink:BiologicalProcess 3-methylquinoline catabolic process The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring. MetaCyc:PWY-721 go-plus.json 3-methylquinoline degradation|3-methylquinoline breakdown|3-methylquinoline catabolism http://purl.obolibrary.org/obo/GO_0019335 UBERON:0004701 biolink:AnatomicalEntity venous system endothelium An endothelium that is part of a venous system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004701 UBERON:0004702 biolink:AnatomicalEntity respiratory system blood vessel endothelium A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004702 GO:0019336 biolink:BiologicalProcess phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. MetaCyc:PHENOLDEG-PWY go-plus.json phenol-containing compound catabolism|phenol-containing compound degradation|phenol-containing compound breakdown http://purl.obolibrary.org/obo/GO_0019336 GO:0019333 biolink:BiologicalProcess denitrification pathway The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen. MetaCyc:DENITRIFICATION-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019333 UBERON:0004700 biolink:AnatomicalEntity arterial system endothelium An endothelium that is part of an arterial system [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004700 GO:0019334 biolink:BiologicalProcess p-cymene catabolic process The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants. MetaCyc:PWY-741 go-plus.json p-cymene degradation|p-cymene breakdown|p-cymene catabolism http://purl.obolibrary.org/obo/GO_0019334 GO:0019331 biolink:BiologicalProcess anaerobic respiration, using ammonium as electron donor The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2. MetaCyc:P303-PWY|Wikipedia:Anammox go-plus.json anammox|anaerobic ammonium oxidation http://purl.obolibrary.org/obo/GO_0019331 GO:0019332 biolink:BiologicalProcess aerobic respiration, using nitrite as electron donor The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species. MetaCyc:P282-PWY go-plus.json nitrite oxidation http://purl.obolibrary.org/obo/GO_0019332 GO:0019330 biolink:BiologicalProcess aldoxime metabolic process The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH. MetaCyc:P345-PWY go-plus.json aldoxime metabolism http://purl.obolibrary.org/obo/GO_0019330 CHEBI:72575 biolink:ChemicalSubstance alarm pheromone go-plus.json http://purl.obolibrary.org/obo/CHEBI_72575 GO:0019350 biolink:BiologicalProcess teichoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues. MetaCyc:TEICHOICACID-PWY go-plus.json teichoic acid formation|teichoic acid biosynthesis|teichoic acid anabolism|teichoic acid synthesis http://purl.obolibrary.org/obo/GO_0019350 CHEBI:72576 biolink:ChemicalSubstance aurones go-plus.json http://purl.obolibrary.org/obo/CHEBI_72576 chebi_ph7_3 CHEBI:72579 biolink:ChemicalSubstance tetrahydrochromenochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_72579 GO:0044313 biolink:BiologicalProcess protein K6-linked deubiquitination A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0044313 GO:0034965 biolink:BiologicalProcess intronic box C/D RNA processing Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA. go-plus.json intronic box C/D snoRNA processing|intronic box C/D sRNA processing http://purl.obolibrary.org/obo/GO_0034965 GO:0044314 biolink:BiologicalProcess protein K27-linked ubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein. go-plus.json protein K27-linked polyubiquitination http://purl.obolibrary.org/obo/GO_0044314 GO:0034966 biolink:BiologicalProcess intronic box H/ACA snoRNA processing Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0034966 GO:0044311 biolink:CellularComponent exoneme A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0044311 GO:0034967 biolink:CellularComponent Set3 complex A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p. go-plus.json SET3C|HDAC3 complex http://purl.obolibrary.org/obo/GO_0034967 GO:0034968 biolink:BiologicalProcess histone lysine methylation The modification of a histone by addition of one or more methyl groups to a lysine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0034968 GO:0044312 biolink:CellularComponent crystalloid A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation. go-plus.json http://purl.obolibrary.org/obo/GO_0044312 GO:0034969 biolink:BiologicalProcess histone arginine methylation The modification of a histone by addition of a methyl group to an arginine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0034969 GO:0044310 biolink:CellularComponent osmiophilic body A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito. go-plus.json http://purl.obolibrary.org/obo/GO_0044310 GO:0044319 biolink:BiologicalProcess wound healing, spreading of cells The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface. go-plus.json cell migration involved in wound healing epiboly http://purl.obolibrary.org/obo/GO_0044319 GO:0034960 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034960 GO:0044317 biolink:CellularComponent rod spherule A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body. go-plus.json rod photoreceptor spherule|rod cell spherule http://purl.obolibrary.org/obo/GO_0044317 GO:0034961 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034961 GO:0044318 biolink:MolecularActivity L-aspartate:fumarate oxidoreductase activity Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate. EC:1.4.3.16 go-plus.json http://purl.obolibrary.org/obo/GO_0044318 GO:0034962 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034962 GO:0019348 biolink:BiologicalProcess dolichol metabolic process The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units. go-plus.json dolichol metabolism http://purl.obolibrary.org/obo/GO_0019348 GO:0044315 biolink:BiologicalProcess protein secretion by the type VII secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system. go-plus.json http://purl.obolibrary.org/obo/GO_0044315 GO:0034963 biolink:BiologicalProcess box C/D RNA processing Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA. go-plus.json box C/D snoRNA processing|box C/D sRNA processing http://purl.obolibrary.org/obo/GO_0034963 GO:0044316 biolink:CellularComponent cone cell pedicle A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL). go-plus.json cone pedicle http://purl.obolibrary.org/obo/GO_0044316 GO:0034964 biolink:BiologicalProcess box H/ACA RNA processing Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA. go-plus.json box H/ACA snoRNA processing|box H/ACA sRNA processing http://purl.obolibrary.org/obo/GO_0034964 GO:0019349 biolink:BiologicalProcess ribitol metabolic process The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin. go-plus.json ribitol metabolism http://purl.obolibrary.org/obo/GO_0019349 GO:0019346 biolink:BiologicalProcess transsulfuration The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes. MetaCyc:PWY-801|Wikipedia:Transsulfuration_pathway go-plus.json transsulphuration|homocysteine-cysteine interconversion http://purl.obolibrary.org/obo/GO_0019346 GO:0019347 biolink:BiologicalProcess GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate. MetaCyc:MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS go-plus.json GDP-alpha-D-mannosylchitobiosyldiphosphodolichol anabolism|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol synthesis|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol formation|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthesis http://purl.obolibrary.org/obo/GO_0019347 GO:0019344 biolink:BiologicalProcess cysteine biosynthetic process The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid. go-plus.json cysteine anabolism|cysteine synthesis|cysteine formation|cysteine biosynthesis http://purl.obolibrary.org/obo/GO_0019344 GO:0019345 biolink:BiologicalProcess cysteine biosynthetic process via S-sulfo-L-cysteine The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine. go-plus.json cysteine formation via S-sulfo-L-cysteine|cysteine synthesis via S-sulfo-L-cysteine|cysteine anabolism via S-sulfo-L-cysteine|cysteine biosynthetic process via S-sulpho-L-cysteine|cysteine biosynthesis via S-sulpho-L-cysteine http://purl.obolibrary.org/obo/GO_0019345 GO:0019342 biolink:BiologicalProcess trypanothione biosynthetic process The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress. MetaCyc:TRYPANOSYN-PWY go-plus.json trypanothione anabolism|trypanothione synthesis|trypanothione formation|trypanothione biosynthesis http://purl.obolibrary.org/obo/GO_0019342 CHEBI:72571 biolink:ChemicalSubstance pro-angiogenic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_72571 CHEBI:72572 biolink:ChemicalSubstance isoflavans go-plus.json http://purl.obolibrary.org/obo/CHEBI_72572 chebi_ph7_3 GO:0019343 biolink:BiologicalProcess cysteine biosynthetic process via cystathionine The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine. go-plus.json cysteine anabolism via cystathionine|cysteine synthesis via cystathionine|cysteine formation via cystathionine http://purl.obolibrary.org/obo/GO_0019343 GO:0019340 biolink:BiologicalProcess dibenzofuran catabolic process The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. MetaCyc:P662-PWY go-plus.json dibenzofuran breakdown|dibenzofuran degradation|dibenzofuran catabolism http://purl.obolibrary.org/obo/GO_0019340 CHEBI:72573 biolink:ChemicalSubstance triazene derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_72573 chebi_ph7_3 GO:0019341 biolink:BiologicalProcess dibenzo-p-dioxin catabolic process The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. MetaCyc:P661-PWY go-plus.json dibenzo-p-dioxin catabolism|dibenzo-p-dioxin degradation|dibenzo-p-dioxin breakdown http://purl.obolibrary.org/obo/GO_0019341 CHEBI:139200 biolink:ChemicalSubstance hydroxy fatty acid anion 26:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_139200 CHEBI:72587 biolink:ChemicalSubstance (R)-noradrenaline(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72587 chebi_ph7_3 CHEBI:72588 biolink:ChemicalSubstance semisynthetic derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_72588 GO:0034954 biolink:MolecularActivity diphenyl ether 2,3-dioxygenase activity Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether. EC:1.14.12.-|UM-BBD_reactionID:r1450 go-plus.json http://purl.obolibrary.org/obo/GO_0034954 GO:0010987 biolink:BiologicalProcess negative regulation of high-density lipoprotein particle clearance Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010987 GO:0044324 biolink:BiologicalProcess regulation of transcription involved in anterior/posterior axis specification Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0044324 GO:0034955 biolink:MolecularActivity 2,3-dihydroxydiphenyl ether dioxygenase activity Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol. EC:1.13.11.-|UM-BBD_reactionID:r1451 go-plus.json http://purl.obolibrary.org/obo/GO_0034955 GO:0044325 biolink:MolecularActivity transmembrane transporter binding Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. go-plus.json ion channel binding http://purl.obolibrary.org/obo/GO_0044325 goslim_chembl GO:0010988 biolink:BiologicalProcess regulation of low-density lipoprotein particle clearance Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010988 GO:0044322 biolink:CellularComponent endoplasmic reticulum quality control compartment A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins. go-plus.json ERQC|ER quality control compartment|ER-derived quality control compartment http://purl.obolibrary.org/obo/GO_0044322 GO:0034956 biolink:MolecularActivity diphenyl ether 1,2-dioxygenase activity Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+. EC:1.13.11.-|UM-BBD_reactionID:r1453 go-plus.json http://purl.obolibrary.org/obo/GO_0034956 GO:0010985 biolink:BiologicalProcess negative regulation of lipoprotein particle clearance Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010985 GO:0044323 biolink:MolecularActivity retinoic acid-responsive element binding Binding to a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind. go-plus.json RARE binding http://purl.obolibrary.org/obo/GO_0044323 GO:0034957 biolink:MolecularActivity 3-nitrophenol nitroreductase activity Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O. UM-BBD_reactionID:r1495 go-plus.json http://purl.obolibrary.org/obo/GO_0034957 GO:0010986 biolink:BiologicalProcess positive regulation of lipoprotein particle clearance Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010986 GO:0044320 biolink:BiologicalProcess cellular response to leptin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0044320 GO:0034958 biolink:MolecularActivity aminohydroquinone monooxygenase activity Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3. EC:3.5.99.-|UM-BBD_reactionID:r1497 go-plus.json http://purl.obolibrary.org/obo/GO_0034958 GO:0044321 biolink:BiologicalProcess response to leptin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]. go-plus.json response to leptin stimulus http://purl.obolibrary.org/obo/GO_0044321 GO:0034959 biolink:BiologicalProcess endothelin maturation The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin. go-plus.json http://purl.obolibrary.org/obo/GO_0034959 GO:0010989 biolink:BiologicalProcess negative regulation of low-density lipoprotein particle clearance Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010989 GO:0009990 biolink:BiologicalProcess contact guidance Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells. go-plus.json http://purl.obolibrary.org/obo/GO_0009990 GO:0010980 biolink:BiologicalProcess positive regulation of vitamin D 24-hydroxylase activity Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D. go-plus.json http://purl.obolibrary.org/obo/GO_0010980 GO:0009991 biolink:BiologicalProcess response to extracellular stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0009991 GO:0019319 biolink:BiologicalProcess hexose biosynthetic process The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. go-plus.json hexose biosynthesis|hexose anabolism|hexose synthesis|hexose formation http://purl.obolibrary.org/obo/GO_0019319 GO:0009992 biolink:BiologicalProcess cellular water homeostasis Any process involved in the maintenance of an internal steady state of water within a cell. go-plus.json cellular osmoregulation http://purl.obolibrary.org/obo/GO_0009992 GO:0009993 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009993 GO:0034950 biolink:MolecularActivity phenylboronic acid monooxygenase activity Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3. UM-BBD_reactionID:r1020 go-plus.json http://purl.obolibrary.org/obo/GO_0034950 GO:0019317 biolink:BiologicalProcess fucose catabolic process The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose). MetaCyc:FUCCAT-PWY go-plus.json fucose breakdown|fucose catabolism|fucose degradation http://purl.obolibrary.org/obo/GO_0019317 GO:0010983 biolink:BiologicalProcess positive regulation of high-density lipoprotein particle clearance Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010983 GO:0044328 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration. go-plus.json canonical Wnt receptor signalling pathway involved in positive regulation of endothelial cell migration|canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0044328 GO:0009994 biolink:BiologicalProcess oocyte differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. go-plus.json oocyte cell differentiation http://purl.obolibrary.org/obo/GO_0009994 GO:0019318 biolink:BiologicalProcess hexose metabolic process The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule. go-plus.json hexose metabolism http://purl.obolibrary.org/obo/GO_0019318 GO:0010984 biolink:BiologicalProcess regulation of lipoprotein particle clearance Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010984 GO:0044329 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion. go-plus.json canonical Wnt receptor signalling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt-activated signaling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0044329 GO:0034951 biolink:MolecularActivity o-hydroxylaminobenzoate mutase activity Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate. MetaCyc:RXN-8846|UM-BBD_reactionID:r1026|EC:5.4.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034951 GO:0009995 biolink:BiologicalProcess soluble molecule recognition The recognition of soluble molecules in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0009995 GO:0009996 biolink:BiologicalProcess negative regulation of cell fate specification Any process that restricts, stops or prevents a cell from adopting a specific cell fate. go-plus.json downregulation of cell fate specification|down-regulation of cell fate specification|suppression of cell fate|inhibition of cell fate specification|down regulation of cell fate specification http://purl.obolibrary.org/obo/GO_0009996 GO:0010981 biolink:BiologicalProcess regulation of cell wall macromolecule metabolic process Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. go-plus.json http://purl.obolibrary.org/obo/GO_0010981 GO:0044326 biolink:CellularComponent dendritic spine neck Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine. NIF_Subcellular:sao1642908940 go-plus.json pedicle|neck|spine neck http://purl.obolibrary.org/obo/GO_0044326 GO:0019315 biolink:BiologicalProcess D-allose biosynthetic process The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose. go-plus.json D-allose biosynthesis|D-allose anabolism|D-allose synthesis|D-allose formation http://purl.obolibrary.org/obo/GO_0019315 GO:0034952 biolink:MolecularActivity malonate semialdehyde decarboxylase activity Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2. UM-BBD_reactionID:r0266 go-plus.json http://purl.obolibrary.org/obo/GO_0034952 GO:0034953 biolink:MolecularActivity perillyl-CoA hydratase activity Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA. UM-BBD_reactionID:r1002 go-plus.json http://purl.obolibrary.org/obo/GO_0034953 GO:0009997 biolink:BiologicalProcess negative regulation of cardioblast cell fate specification Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json downregulation of cardioblast cell fate specification|down-regulation of cardioblast cell fate specification|suppression of cardioblast cell fate|inhibition of cardioblast cell fate specification|down regulation of cardioblast cell fate specification http://purl.obolibrary.org/obo/GO_0009997 GO:0044327 biolink:CellularComponent dendritic spine head Distal part of the dendritic spine, that carries the post-synaptic density. NIF_Subcellular:sao952643730 go-plus.json spine head http://purl.obolibrary.org/obo/GO_0044327 GO:0019316 biolink:BiologicalProcess D-allose catabolic process The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose. MetaCyc:PWY0-44 go-plus.json D-allose breakdown|D-allose catabolism|D-allose degradation http://purl.obolibrary.org/obo/GO_0019316 GO:0010982 biolink:BiologicalProcess regulation of high-density lipoprotein particle clearance Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0010982 GO:0009998 biolink:BiologicalProcess negative regulation of retinal cone cell fate specification Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell. go-plus.json suppression of retinal cone cell fate|negative regulation of retina cone cell fate specification|suppression of retina cone cell fate|downregulation of retinal cone cell fate specification|down regulation of retinal cone cell fate specification|inhibition of retinal cone cell fate specification|down-regulation of retinal cone cell fate specification http://purl.obolibrary.org/obo/GO_0009998 GO:0019313 biolink:BiologicalProcess allose metabolic process The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. go-plus.json allose metabolism http://purl.obolibrary.org/obo/GO_0019313 GO:0009999 biolink:BiologicalProcess negative regulation of auditory receptor cell fate specification Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell. go-plus.json downregulation of auditory receptor cell fate specification|negative regulation of auditory hair cell fate specification|down-regulation of auditory receptor cell fate specification|suppression of auditory receptor cell fate|inhibition of auditory receptor cell fate specification|suppression of hair cell fate|down regulation of auditory receptor cell fate specification http://purl.obolibrary.org/obo/GO_0009999 GO:0019314 biolink:BiologicalProcess D-allose metabolic process The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose. go-plus.json D-allose metabolism http://purl.obolibrary.org/obo/GO_0019314 CHEBI:1060 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-arabinonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1060 GO:0019311 biolink:BiologicalProcess sorbose metabolic process The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. go-plus.json sorbose metabolism http://purl.obolibrary.org/obo/GO_0019311 GO:0019312 biolink:BiologicalProcess L-sorbose metabolic process The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol. MetaCyc:P302-PWY go-plus.json L-sorbose metabolism http://purl.obolibrary.org/obo/GO_0019312 CHEBI:72581 biolink:ChemicalSubstance rotenones go-plus.json http://purl.obolibrary.org/obo/CHEBI_72581 chebi_ph7_3 CHEBI:72582 biolink:ChemicalSubstance Man-1-6-Ins-1-P-Cer(t18:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_72582 chebi_ph7_3 GO:0019310 biolink:BiologicalProcess inositol catabolic process The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. MetaCyc:P562-PWY go-plus.json inositol catabolism|myo-inositol catabolic process|vitamin Bh catabolism|myo-inositol catabolism|inositol degradation|inositol breakdown|vitamin Bh catabolic process http://purl.obolibrary.org/obo/GO_0019310 CHEBI:72584 biolink:ChemicalSubstance pentahydroxyflavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_72584 GO:0034943 biolink:MolecularActivity trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi. UM-BBD_reactionID:r0989 go-plus.json http://purl.obolibrary.org/obo/GO_0034943 GO:0044335 biolink:BiologicalProcess canonical Wnt signaling pathway involved in neural crest cell differentiation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation. go-plus.json canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|canonical Wnt-activated signaling pathway involved in neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0044335 GO:0010998 biolink:BiologicalProcess regulation of translational initiation by eIF2 alpha phosphorylation Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha. go-plus.json eIF2 alpha phosphorylation in response to stress|regulation of translational initiation by eIF2 alpha phosphorylation in response to stress http://purl.obolibrary.org/obo/GO_0010998 GO:0010999 biolink:BiologicalProcess regulation of eIF2 alpha phosphorylation by heme Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels. go-plus.json http://purl.obolibrary.org/obo/GO_0010999 GO:0044336 biolink:BiologicalProcess canonical Wnt signaling pathway involved in negative regulation of apoptotic process The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process. go-plus.json canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis|canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in negative regulation of apoptosis http://purl.obolibrary.org/obo/GO_0044336 GO:0034944 biolink:MolecularActivity 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+. UM-BBD_reactionID:r0986 go-plus.json http://purl.obolibrary.org/obo/GO_0034944 GO:0044333 biolink:BiologicalProcess Wnt signaling pathway involved in digestive tract morphogenesis The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract. go-plus.json Wnt receptor signalling pathway involved in digestive tract morphogenesis|Wnt receptor signaling pathway involved in digestive tract morphogenesis|Wnt-activated signaling pathway involved in digestive tract morphogenesis http://purl.obolibrary.org/obo/GO_0044333 GO:0034945 biolink:MolecularActivity 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA. UM-BBD_reactionID:r0987|EC:2.3.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034945 GO:0010996 biolink:BiologicalProcess response to auditory stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus. go-plus.json response to sound stimulus|response to sound http://purl.obolibrary.org/obo/GO_0010996 GO:0010997 biolink:MolecularActivity anaphase-promoting complex binding Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. go-plus.json APC binding http://purl.obolibrary.org/obo/GO_0010997 GO:0044334 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition. go-plus.json canonical Wnt receptor signalling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt-activated signaling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0044334 GO:0034946 biolink:MolecularActivity 3-isopropylbut-3-enoyl-CoA thioesterase activity Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH. UM-BBD_reactionID:r0994 go-plus.json http://purl.obolibrary.org/obo/GO_0034946 GO:0044331 biolink:BiologicalProcess cell-cell adhesion mediated by cadherin The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains. go-plus.json http://purl.obolibrary.org/obo/GO_0044331 CHEBI:47571 biolink:ChemicalSubstance N-acetyl-alpha-D-muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47571 GO:0034947 biolink:MolecularActivity terephthalate decarboxylase activity Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-. UM-BBD_reactionID:r0321 go-plus.json http://purl.obolibrary.org/obo/GO_0034947 GO:0044332 biolink:BiologicalProcess Wnt signaling pathway involved in dorsal/ventral axis specification The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis. go-plus.json Wnt receptor signalling pathway involved in dorsal/ventral axis specification|Wnt receptor signaling pathway involved in dorsal/ventral axis specification|Wnt-activated signaling pathway involved in dorsal/ventral axis specification http://purl.obolibrary.org/obo/GO_0044332 GO:0034948 biolink:MolecularActivity 2,6-dihydroxypseudooxynicotine hydrolase activity Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate. UM-BBD_reactionID:r0482|EC:3.7.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0034948 GO:0034949 biolink:MolecularActivity 1,1-dichloroethane reductive dehalogenase activity Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl. EC:1.97.1.-|UM-BBD_reactionID:r1008 go-plus.json http://purl.obolibrary.org/obo/GO_0034949 GO:0044330 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of wound healing The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing. go-plus.json canonical Wnt receptor signaling pathway involved in positive regulation of wound healing|canonical Wnt receptor signalling pathway involved in positive regulation of wound healing|canonical Wnt-activated signaling pathway involved in positive regulation of wound healing http://purl.obolibrary.org/obo/GO_0044330 GO:0010990 biolink:BiologicalProcess regulation of SMAD protein complex assembly Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010990 GO:0010991 biolink:BiologicalProcess negative regulation of SMAD protein complex assembly Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010991 GO:0044339 biolink:BiologicalProcess canonical Wnt signaling pathway involved in osteoblast differentiation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation. go-plus.json canonical Wnt receptor signalling pathway involved in osteoblast differentiation|canonical Wnt-activated signaling pathway involved in osteoblast differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation http://purl.obolibrary.org/obo/GO_0044339 GO:0010994 biolink:BiologicalProcess free ubiquitin chain polymerization The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0010994 GO:0019328 biolink:BiologicalProcess anaerobic gallate catabolic process The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen. MetaCyc:P3-PWY go-plus.json anaerobic gallic acid catabolism|anaerobic gallic acid catabolic process|gallate fermentation|anaerobic gallate degradation|anaerobic gallate catabolism|anaerobic gallate breakdown http://purl.obolibrary.org/obo/GO_0019328 GO:0034940 biolink:MolecularActivity 5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3. UM-BBD_reactionID:r0984 go-plus.json http://purl.obolibrary.org/obo/GO_0034940 GO:0010995 biolink:BiologicalProcess free ubiquitin chain depolymerization The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down. go-plus.json http://purl.obolibrary.org/obo/GO_0010995 GO:0019329 biolink:BiologicalProcess ammonia oxidation The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons. go-plus.json http://purl.obolibrary.org/obo/GO_0019329 GO:0044337 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of apoptotic process The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process. go-plus.json canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in positive regulation of apoptosis|canonical Wnt-activated signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis http://purl.obolibrary.org/obo/GO_0044337 GO:0034941 biolink:MolecularActivity pyrrole-2-carboxylate decarboxylase activity Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2. UM-BBD_reactionID:r0970|EC:4.1.1.93 go-plus.json http://purl.obolibrary.org/obo/GO_0034941 GO:0010992 biolink:BiologicalProcess ubiquitin recycling Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates. go-plus.json ubiquitin homeostasis|regulation of ubiquitin homeostasis http://purl.obolibrary.org/obo/GO_0010992 GO:0019326 biolink:BiologicalProcess nitrotoluene metabolic process The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached. go-plus.json nitrotoluene metabolism http://purl.obolibrary.org/obo/GO_0019326 GO:0019327 biolink:BiologicalProcess lead sulfide oxidation The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate. MetaCyc:P301-PWY go-plus.json lead sulphide oxidation|oxidation of lead sulfide|oxidation of galena http://purl.obolibrary.org/obo/GO_0019327 GO:0044338 biolink:BiologicalProcess canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation. go-plus.json canonical Wnt receptor signalling pathway involved in mesenchymal stem cell differentiation|canonical Wnt-activated signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation http://purl.obolibrary.org/obo/GO_0044338 GO:0034942 biolink:MolecularActivity cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi. UM-BBD_reactionID:r0988 go-plus.json http://purl.obolibrary.org/obo/GO_0034942 GO:0010993 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010993 GO:0019324 biolink:BiologicalProcess L-lyxose metabolic process The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose. MetaCyc:LYXMET-PWY go-plus.json L-lyxose metabolism http://purl.obolibrary.org/obo/GO_0019324 GO:0019325 biolink:BiologicalProcess anaerobic fructose catabolic process The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen. MetaCyc:ANAEROFRUCAT-PWY go-plus.json anaerobic fructose breakdown|anaerobic fructose catabolism|anaerobic fructose degradation http://purl.obolibrary.org/obo/GO_0019325 GO:0019322 biolink:BiologicalProcess pentose biosynthetic process The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. go-plus.json pentose synthesis|pentose formation|pentose biosynthesis|pentose anabolism http://purl.obolibrary.org/obo/GO_0019322 GO:0019323 biolink:BiologicalProcess pentose catabolic process The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. go-plus.json pentose degradation|pentose catabolism|pentose breakdown http://purl.obolibrary.org/obo/GO_0019323 GO:0019320 biolink:BiologicalProcess hexose catabolic process The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. go-plus.json hexose degradation|hexose catabolism|hexose breakdown http://purl.obolibrary.org/obo/GO_0019320 CHEBI:72593 biolink:ChemicalSubstance 15-ketoprostaglandin F1alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_72593 GO:0019321 biolink:BiologicalProcess pentose metabolic process The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. go-plus.json pentose metabolism http://purl.obolibrary.org/obo/GO_0019321 CHEBI:72596 biolink:ChemicalSubstance papulacandin go-plus.json http://purl.obolibrary.org/obo/CHEBI_72596 UBERON:0004738 biolink:AnatomicalEntity metanephric juxtaglomerular apparatus juxtaglomerular apparatus of the mature vertebrate kidney, or metanephros. go-plus.json juxtaglomerular apparatus of metanephros http://purl.obolibrary.org/obo/UBERON_0004738 UBERON:0004739 biolink:AnatomicalEntity pronephric glomerulus The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment. go-plus.json corpuscle|pronephric glomeruli|glomera|pronephric glomus|glomerulus of pronephros|glomus|pronephric glomera http://purl.obolibrary.org/obo/UBERON_0004739 UBERON:0004736 biolink:AnatomicalEntity metanephric glomerulus glomerulus of the mature vertebrate kidney, or metanephros. go-plus.json glomerulus of metanephros http://purl.obolibrary.org/obo/UBERON_0004736 UBERON:0004737 biolink:AnatomicalEntity metanephric collecting duct A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]. go-plus.json collecting duct of metanephros|metanephric collecting tubule http://purl.obolibrary.org/obo/UBERON_0004737 GO:0034932 biolink:MolecularActivity 1-methoxypyrene 6,7-monooxygenase activity Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O. UM-BBD_reactionID:r0954 go-plus.json http://purl.obolibrary.org/obo/GO_0034932 GO:0010965 biolink:BiologicalProcess regulation of mitotic sister chromatid separation Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0010965 GO:0044346 biolink:BiologicalProcess fibroblast apoptotic process Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. go-plus.json fibroblast apoptosis http://purl.obolibrary.org/obo/GO_0044346 GO:0044347 biolink:BiologicalProcess cell wall polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides. go-plus.json cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_0044347 GO:0034933 biolink:MolecularActivity 1-hydroxy-6-methoxypyrene methyltransferase activity Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX. UM-BBD_reactionID:r0956 go-plus.json http://purl.obolibrary.org/obo/GO_0034933 GO:0010966 biolink:BiologicalProcess regulation of phosphate transport Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010966 GO:0034934 biolink:MolecularActivity phenanthrene-4-carboxylate dioxygenase activity Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate. UM-BBD_reactionID:r0939|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034934 GO:0044344 biolink:BiologicalProcess cellular response to fibroblast growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus. go-plus.json cellular response to FGF stimulus http://purl.obolibrary.org/obo/GO_0044344 GO:0010963 biolink:BiologicalProcess regulation of L-arginine import Any process that modulates the frequency, rate or extent of L-arginine import. L-arginine import is the directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0010963 GO:0034935 biolink:MolecularActivity tetrachlorobenzene dioxygenase activity Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+. UM-BBD_reactionID:r0957|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034935 GO:0010964 biolink:BiologicalProcess regulation of heterochromatin assembly by small RNA Any process that modulates the frequency, rate or extent of heterochromatin assembly by small RNA. go-plus.json regulation of chromatin silencing by small RNA|regulation of RNAi-mediated heterochromatin assembly http://purl.obolibrary.org/obo/GO_0010964 GO:0044345 biolink:BiologicalProcess stromal-epithelial cell signaling involved in prostate gland development The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development. go-plus.json stromal-epithelial cell signalling involved in prostate gland development http://purl.obolibrary.org/obo/GO_0044345 GO:0034936 biolink:MolecularActivity 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+. UM-BBD_reactionID:r0959|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034936 GO:0044342 biolink:BiologicalProcess type B pancreatic cell proliferation The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. go-plus.json pancreatic beta cell proliferation|pancreatic B cell proliferation http://purl.obolibrary.org/obo/GO_0044342 GO:0010969 biolink:BiologicalProcess regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0010969 GO:0044343 biolink:BiologicalProcess canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin. go-plus.json canonical Wnt receptor signalling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of pancreatic B cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of pancreatic B cell proliferation http://purl.obolibrary.org/obo/GO_0044343 GO:0034937 biolink:MolecularActivity perchlorate reductase activity Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O. EC:1.97.1.-|UM-BBD_reactionID:r0980 go-plus.json http://purl.obolibrary.org/obo/GO_0034937 GO:0010967 biolink:BiologicalProcess regulation of polyamine biosynthetic process Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. go-plus.json http://purl.obolibrary.org/obo/GO_0010967 GO:0044340 biolink:BiologicalProcess canonical Wnt signaling pathway involved in regulation of cell proliferation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation. go-plus.json canonical Wnt receptor signaling pathway involved in regulation of cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of cell proliferation http://purl.obolibrary.org/obo/GO_0044340 GO:0034938 biolink:MolecularActivity pyrrole-2-carboxylate monooxygenase activity Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O. UM-BBD_reactionID:r0968|EC:1.14.14.- go-plus.json http://purl.obolibrary.org/obo/GO_0034938 CHEBI:23591 biolink:ChemicalSubstance dehydroamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23591 GO:0034939 biolink:MolecularActivity 5-hydroxypyrrole-2-carboxylate tautomerase activity Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate. UM-BBD_reactionID:r0969 go-plus.json http://purl.obolibrary.org/obo/GO_0034939 GO:0010968 biolink:BiologicalProcess regulation of microtubule nucleation Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010968 GO:0044341 biolink:BiologicalProcess sodium-dependent phosphate transport The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions. go-plus.json http://purl.obolibrary.org/obo/GO_0044341 GO:0009970 biolink:BiologicalProcess cellular response to sulfate starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate. go-plus.json cellular response to sulphate starvation http://purl.obolibrary.org/obo/GO_0009970 GO:0009971 biolink:BiologicalProcess anastral spindle assembly involved in male meiosis The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0009971 GO:0009972 biolink:BiologicalProcess cytidine deamination The removal of amino group in the presence of water. go-plus.json http://purl.obolibrary.org/obo/GO_0009972 GO:0010961 biolink:BiologicalProcess cellular magnesium ion homeostasis Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010961 GO:0010962 biolink:BiologicalProcess regulation of glucan biosynthetic process Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. go-plus.json http://purl.obolibrary.org/obo/GO_0010962 GO:0009973 biolink:MolecularActivity adenylyl-sulfate reductase activity Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor. EC:1.8.99.2|RHEA:24240|MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN go-plus.json AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)|APS-reductase|AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)|APS reductase activity|adenylyl-sulphate reductase activity|adenosine phosphosulfate reductase activity|adenosine 5'-phosphosulfate reductase http://purl.obolibrary.org/obo/GO_0009973 GO:0009974 biolink:MolecularActivity zeinoxanthin epsilon hydroxylase activity Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene. EC:1.14.14.158|MetaCyc:RXN-5962|RHEA:57352 go-plus.json http://purl.obolibrary.org/obo/GO_0009974 GO:0034930 biolink:MolecularActivity 1-hydroxypyrene sulfotransferase activity Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX. UM-BBD_reactionID:r0952 go-plus.json http://purl.obolibrary.org/obo/GO_0034930 GO:0044348 biolink:BiologicalProcess plant-type cell wall cellulose catabolic process The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall. go-plus.json plant-type cell wall polysaccharide breakdown http://purl.obolibrary.org/obo/GO_0044348 GO:0044349 biolink:BiologicalProcess DNA excision The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised. go-plus.json http://purl.obolibrary.org/obo/GO_0044349 GO:0034931 biolink:MolecularActivity 1-hydroxypyrene methyltransferase activity Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX. UM-BBD_reactionID:r0953 go-plus.json http://purl.obolibrary.org/obo/GO_0034931 GO:0009975 biolink:MolecularActivity cyclase activity Catalysis of a ring closure reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0009975 goslim_pir GO:0010960 biolink:BiologicalProcess magnesium ion homeostasis Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0010960 UBERON:0004745 biolink:AnatomicalEntity parasphenoid A tooth- or denticle-covered plate which is attached to the sphenoid stem[Palaeos]. go-plus.json parabasale|keilbein|os sphenoideum|os parasphenoidale http://purl.obolibrary.org/obo/UBERON_0004745 GO:0009976 biolink:MolecularActivity tocopherol cyclase activity Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol). go-plus.json http://purl.obolibrary.org/obo/GO_0009976 GO:0009977 biolink:MolecularActivity proton motive force dependent protein transmembrane transporter activity Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane. go-plus.json delta-pH-dependent protein transporter activity|pH-dependent protein transporter activity|arginine targeting transmembrane transporter activity|twin-arginine targeting transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0009977 GO:0009978 biolink:MolecularActivity allene oxide synthase activity Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O. MetaCyc:RXN1F-19|RHEA:25074 go-plus.json linoleate hydroperoxide isomerase|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|HPI|linoleic acid hydroperoxide isomerase http://purl.obolibrary.org/obo/GO_0009978 GO:0009979 biolink:MolecularActivity 16:0 monogalactosyldiacylglycerol desaturase activity Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0009979 UBERON:0004742 biolink:AnatomicalEntity dentary The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]. go-plus.json dentaries|os dentale|dentale|sur-angulaire|dentary bone http://purl.obolibrary.org/obo/UBERON_0004742 GO:0034929 biolink:MolecularActivity 1-hydroxypyrene 7,8-monooxygenase activity Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O. UM-BBD_reactionID:r0949 go-plus.json http://purl.obolibrary.org/obo/GO_0034929 GO:0044350 biolink:BiologicalProcess micropinocytosis An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm. go-plus.json clathrin-independent pinocytosis|single-organism micropinocytosis http://purl.obolibrary.org/obo/GO_0044350 UBERON:0004729 biolink:AnatomicalEntity nematode larval stage Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004729 UBERON:0004727 biolink:AnatomicalEntity cochlear nerve A nerve in the head that carries signals from the cochlea of the inner ear to the brain. It is part of the vestibulocochlear nerve, the 8th cranial nerve which is found in higher vertebrates; the other portion of the 8th cranial nerve is the vestibular nerve which carries spatial orientation information from the semicircular canals. The cochlear nerve is a sensory nerve, one which conducts to the brain information about the environment, in this case acoustic energy impinging on the tympanic membrane. The cochlear nerve arises from within the cochlea and extends to the brainstem, where its fibers make contact with the cochlear nucleus, the next stage of neural processing in the auditory system[WP]. go-plus.json auditory nerve|vestibulocochlear VIII nerve cochlear component|vestibulocochlear nerve cochlear component|cochlear root of acoustic nerve|cochlear component|cochlear root of eighth cranial nerve|nervus vestibulocochlearis http://purl.obolibrary.org/obo/UBERON_0004727 UBERON:0004725 biolink:AnatomicalEntity piriform cortex the subdivision of the laminated olfactory cortex with only three main layers that receive monosynaptic input from the olfactory bulb via the lateral olfactory tract; it is located bilaterally in the ventrolateral forebrain and is commonly divided into anterior and posterior regions go-plus.json paleopallium|regio praepiriformis|pyriform lobe|cortex piriformis|eupalaeocortex|olfactory pallium|pyriform cortex|primary olfactory areas|piriform area|piriform lobe|primary olfactory cortex|palaeocortex II|area prepiriformis http://purl.obolibrary.org/obo/UBERON_0004725 GO:0034921 biolink:MolecularActivity cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-. UM-BBD_reactionID:r0935 go-plus.json http://purl.obolibrary.org/obo/GO_0034921 GO:0010976 biolink:BiologicalProcess positive regulation of neuron projection development Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). go-plus.json positive regulation of neurite biosynthesis|positive regulation of neurite formation|positive regulation of neurite growth|positive regulation of neurite development http://purl.obolibrary.org/obo/GO_0010976 GO:0044357 biolink:BiologicalProcess regulation of rRNA stability Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs. go-plus.json regulation of ribosomal RNA stability http://purl.obolibrary.org/obo/GO_0044357 GO:0044358 biolink:BiologicalProcess envenomation resulting in hemorrhagic damage to other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044358 GO:0034922 biolink:MolecularActivity 4,5-dihydroxypyrene dioxygenase activity Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+. UM-BBD_reactionID:r0936|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034922 GO:0010977 biolink:BiologicalProcess negative regulation of neuron projection development Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). go-plus.json negative regulation of neurite biosynthesis|negative regulation of neurite development|negative regulation of neurite growth|growth cone collapse|negative regulation of neurite formation http://purl.obolibrary.org/obo/GO_0010977 GO:0034923 biolink:MolecularActivity phenanthrene-4,5-dicarboxylate decarboxylase activity Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2. UM-BBD_reactionID:r0937 go-plus.json http://purl.obolibrary.org/obo/GO_0034923 GO:0010974 biolink:BiologicalProcess negative regulation of division septum assembly Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. go-plus.json negative regulation of division septum formation|inhibition of division septum assembly involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_0010974 GO:0044355 biolink:BiologicalProcess clearance of foreign intracellular DNA A defense process that protects an organism from invading foreign DNA. go-plus.json clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine http://purl.obolibrary.org/obo/GO_0044355 GO:0010975 biolink:BiologicalProcess regulation of neuron projection development Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). go-plus.json regulation of neurite formation|regulation of neurite biosynthesis|regulation of neurite growth|regulation of neurite development http://purl.obolibrary.org/obo/GO_0010975 GO:0044356 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044356 GO:0034924 biolink:MolecularActivity cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2. UM-BBD_reactionID:r0940 go-plus.json http://purl.obolibrary.org/obo/GO_0034924 GO:0034925 biolink:MolecularActivity pyrene 4,5-monooxygenase activity Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O. UM-BBD_reactionID:r0941 go-plus.json http://purl.obolibrary.org/obo/GO_0034925 GO:0044353 biolink:CellularComponent micropinosome A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0044353 GO:0044354 biolink:CellularComponent macropinosome A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0044354 GO:0034926 biolink:MolecularActivity pyrene-4,5-epoxide hydrolase activity Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene. UM-BBD_reactionID:r0942 go-plus.json http://purl.obolibrary.org/obo/GO_0034926 GO:0044351 biolink:BiologicalProcess macropinocytosis An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size. go-plus.json clathrin-independent pinocytosis|single-organism macropinocytosis http://purl.obolibrary.org/obo/GO_0044351 GO:0010978 biolink:BiologicalProcess obsolete gene silencing involved in chronological cell aging OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation. go-plus.json http://purl.obolibrary.org/obo/GO_0010978 GO:0034927 biolink:MolecularActivity pyrene 1,2-monooxygenase activity Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O. UM-BBD_reactionID:r0943 go-plus.json http://purl.obolibrary.org/obo/GO_0034927 GO:0010979 biolink:BiologicalProcess regulation of vitamin D 24-hydroxylase activity Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D. go-plus.json http://purl.obolibrary.org/obo/GO_0010979 GO:0044352 biolink:CellularComponent pinosome A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis. NIF_Subcellular:sao1925368674 go-plus.json pinocytic vesicle http://purl.obolibrary.org/obo/GO_0044352 GO:0034928 biolink:MolecularActivity 1-hydroxypyrene 6,7-monooxygenase activity Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O. UM-BBD_reactionID:r0946 go-plus.json http://purl.obolibrary.org/obo/GO_0034928 GO:0009980 biolink:MolecularActivity obsolete glutamate carboxypeptidase activity OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups. go-plus.json N-pteroyl-L-glutamate hydrolase activity|carboxypeptidase G activity|carboxypeptidase G1 activity|carboxypeptidase G2 activity|glutamate carboxypeptidase activity|glutamyl carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0009980 GO:0009981 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009981 GO:0019308 biolink:BiologicalProcess dTDP-mannose biosynthetic process The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate. go-plus.json dTDP-mannose anabolism|dTDP-mannose synthesis|dTDP-mannose biosynthesis|dTDP-mannose formation http://purl.obolibrary.org/obo/GO_0019308 GO:0019309 biolink:BiologicalProcess mannose catabolic process The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. MetaCyc:MANNCAT-PWY go-plus.json mannose catabolism|mannose degradation|mannose breakdown http://purl.obolibrary.org/obo/GO_0019309 GO:0009982 biolink:MolecularActivity pseudouridine synthase activity Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. Reactome:R-HSA-6782381|Reactome:R-HSA-6790905|Reactome:R-HSA-8870289|Reactome:R-HSA-6787566|Reactome:R-HSA-6786583 go-plus.json http://purl.obolibrary.org/obo/GO_0009982 GO:0010972 biolink:BiologicalProcess negative regulation of G2/M transition of mitotic cell cycle Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. go-plus.json negative regulation of mitotic entry http://purl.obolibrary.org/obo/GO_0010972 GO:0009983 biolink:MolecularActivity obsolete tyrosine aminopeptidase activity OBSOLETE. Catalysis of the release of N-terminal tyrosine from a peptide. go-plus.json tyrosine aminopeptidase activity http://purl.obolibrary.org/obo/GO_0009983 GO:0019306 biolink:BiologicalProcess GDP-D-rhamnose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate. MetaCyc:GDPRHAMSYN-PWY go-plus.json GDP-D-rhamnose biosynthesis|GDP-D-rhamnose anabolism|GDP-D-rhamnose synthesis|GDP-D-rhamnose formation http://purl.obolibrary.org/obo/GO_0019306 GO:0019307 biolink:BiologicalProcess mannose biosynthetic process The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. go-plus.json mannose synthesis|mannose biosynthesis|mannose formation|mannose anabolism http://purl.obolibrary.org/obo/GO_0019307 GO:0009984 biolink:MolecularActivity obsolete adenylate forming enzyme activity OBSOLETE. Catalysis of the reaction: substrate + ATP = substrate-AMP + diphosphate. go-plus.json adenylate forming enzyme activity http://purl.obolibrary.org/obo/GO_0009984 GO:0010973 biolink:BiologicalProcess positive regulation of division septum assembly Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. go-plus.json positive regulation of division septum formation involved in cell cycle cytokinesis|positive regulation of division septum formation|upregulation of mitotic division septum assembly http://purl.obolibrary.org/obo/GO_0010973 GO:0009985 biolink:MolecularActivity obsolete dihydroflavonol(thiole) lyase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json dihydroflavonol(thiole) lyase activity http://purl.obolibrary.org/obo/GO_0009985 GO:0044359 biolink:BiologicalProcess modulation of molecular function in other organism The process in which an organism effects a change in the function of proteins in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044359 GO:0010970 biolink:BiologicalProcess transport along microtubule The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. go-plus.json movement along microtubule|microtubule-based transport|establishment of localization by movement along microtubule http://purl.obolibrary.org/obo/GO_0010970 GO:0019304 biolink:BiologicalProcess anaerobic rhamnose catabolic process The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen. go-plus.json anaerobic rhamnose degradation|anaerobic rhamnose breakdown|anaerobic rhamnose catabolism http://purl.obolibrary.org/obo/GO_0019304 GO:0009986 biolink:CellularComponent cell surface The external part of the cell wall and/or plasma membrane. go-plus.json cell associated|cell bound http://purl.obolibrary.org/obo/GO_0009986 goslim_pir GO:0019305 biolink:BiologicalProcess dTDP-rhamnose biosynthetic process The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate. MetaCyc:DTDPRHAMSYN-PWY|MetaCyc:PWY-3221 go-plus.json dTDP-rhamnose anabolism|dTDP-rhamnose synthesis|dTDP-rhamnose formation|dTDP-rhamnose biosynthesis http://purl.obolibrary.org/obo/GO_0019305 GO:0010971 biolink:BiologicalProcess positive regulation of G2/M transition of mitotic cell cycle Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. go-plus.json positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle|positive regulation of mitotic entry http://purl.obolibrary.org/obo/GO_0010971 GO:0034920 biolink:MolecularActivity pyrene dioxygenase activity Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene. UM-BBD_reactionID:r0934|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0034920 GO:0009987 biolink:BiologicalProcess cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. go-plus.json cell physiology|cellular physiological process|single-organism cellular process|cell growth and/or maintenance http://purl.obolibrary.org/obo/GO_0009987 goslim_plant UBERON:0004734 biolink:AnatomicalEntity gastrula Organism at the gastrula stage. go-plus.json trilaminar germ|blastocystis trilaminaris|trilaminar disc|tri-laminar disk|trilaminar blastoderm|trilaminar blastocyst|tri-laminar disc|gastrula embryo|trilaminar disk http://purl.obolibrary.org/obo/UBERON_0004734 GO:0019302 biolink:BiologicalProcess D-ribose biosynthetic process The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose). go-plus.json D-ribose anabolism|D-ribose synthesis|D-ribose formation|D-ribose biosynthesis http://purl.obolibrary.org/obo/GO_0019302 GO:0009988 biolink:BiologicalProcess cell-cell recognition Cell recognition between cells. May involve the formation of specialized cell junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0009988 GO:0019303 biolink:BiologicalProcess D-ribose catabolic process The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose). MetaCyc:RIBOKIN-PWY go-plus.json D-ribose catabolism|D-ribose degradation|D-ribose breakdown http://purl.obolibrary.org/obo/GO_0019303 UBERON:0004732 biolink:AnatomicalEntity segmental subdivision of nervous system Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres. go-plus.json neuromere http://purl.obolibrary.org/obo/UBERON_0004732 GO:0019300 biolink:BiologicalProcess rhamnose biosynthetic process The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose. go-plus.json rhamnose biosynthesis|rhamnose anabolism|rhamnose synthesis|rhamnose formation http://purl.obolibrary.org/obo/GO_0019300 GO:0009989 biolink:BiologicalProcess cell-matrix recognition Cell recognition that involves the interaction of the cell with the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0009989 UBERON:0004733 biolink:AnatomicalEntity segmental subdivision of hindbrain An organ subunit that is part of a hindbrain [Automatically generated definition]. go-plus.json hindbrain segment|segment of hindbrain http://purl.obolibrary.org/obo/UBERON_0004733 GO:0019301 biolink:BiologicalProcess rhamnose catabolic process The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose. MetaCyc:RHAMCAT-PWY go-plus.json rhamnose degradation|rhamnose catabolism|rhamnose breakdown http://purl.obolibrary.org/obo/GO_0019301 UBERON:0004731 biolink:AnatomicalEntity neuromere A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres). go-plus.json neural segment|neuromeres|neural metamere|neural tube metameric segment|neuromere|neural tube segment http://purl.obolibrary.org/obo/UBERON_0004731 GO:0044360 biolink:BiologicalProcess modulation of voltage-gated potassium channel activity in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044360 GO:0034918 biolink:MolecularActivity 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-. UM-BBD_reactionID:r0930 go-plus.json http://purl.obolibrary.org/obo/GO_0034918 GO:0044361 biolink:BiologicalProcess negative regulation of voltage-gated potassium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044361 GO:0034919 biolink:MolecularActivity butyryl-CoA 2-C-propionyltransferase activity Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA. UM-BBD_reactionID:r0931 go-plus.json http://purl.obolibrary.org/obo/GO_0034919 GO:0010949 biolink:BiologicalProcess negative regulation of intestinal phytosterol absorption Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0010949 UBERON:0004716 biolink:AnatomicalEntity conceptus The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. go-plus.json embryo plus adnexa http://purl.obolibrary.org/obo/UBERON_0004716 GO:0034910 biolink:MolecularActivity 6-hydroxy-3-succinoylpyridine hydrolase activity Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine. UM-BBD_reactionID:r1442 go-plus.json http://purl.obolibrary.org/obo/GO_0034910 GO:0010943 biolink:MolecularActivity NADPH pyrophosphatase activity Catalysis of the reaction: NADPH + H2O = NMNH + ADP. go-plus.json http://purl.obolibrary.org/obo/GO_0010943 GO:0044368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044368 GO:0034911 biolink:MolecularActivity phthalate 3,4-dioxygenase activity Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+. EC:1.14.12.-|UM-BBD_reactionID:r1444 go-plus.json http://purl.obolibrary.org/obo/GO_0034911 GO:0010944 biolink:BiologicalProcess negative regulation of transcription by competitive promoter binding Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site. go-plus.json http://purl.obolibrary.org/obo/GO_0010944 GO:0044369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044369 GO:0034912 biolink:MolecularActivity phthalate 3,4-cis-dihydrodiol dehydrogenase activity Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+. MetaCyc:RXN5F9-56|UM-BBD_reactionID:r1445 go-plus.json http://purl.obolibrary.org/obo/GO_0034912 GO:0010941 biolink:BiologicalProcess regulation of cell death Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0010941 GO:0044366 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044366 GO:0034913 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034913 GO:0010942 biolink:BiologicalProcess positive regulation of cell death Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0010942 GO:0044367 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044367 GO:0010947 biolink:BiologicalProcess negative regulation of meiotic joint molecule formation Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. go-plus.json http://purl.obolibrary.org/obo/GO_0010947 GO:0034914 biolink:MolecularActivity trinitrophenol hydride denitratase activity Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP. UM-BBD_reactionID:r1448|EC:1.7.99.- go-plus.json 2,4,6-trinitrophenol hydride denitratase activity|TNP hydride denitratase activity http://purl.obolibrary.org/obo/GO_0034914 GO:0044364 biolink:BiologicalProcess disruption of cells of other organism A process in which an organism has a negative effect on the functioning of the second organism's cells. go-plus.json http://purl.obolibrary.org/obo/GO_0044364 GO:0044365 biolink:BiologicalProcess envenomation resulting in modulation of platelet aggregation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism. go-plus.json envenomation resulting in regulation of platelet aggregation in other organism http://purl.obolibrary.org/obo/GO_0044365 GO:0034915 biolink:MolecularActivity 2-methylhexanoyl-CoA C-acetyltransferase activity Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA. EC:2.3.1.-|UM-BBD_reactionID:r0927 go-plus.json http://purl.obolibrary.org/obo/GO_0034915 GO:0010948 biolink:BiologicalProcess negative regulation of cell cycle process Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. go-plus.json http://purl.obolibrary.org/obo/GO_0010948 GO:0044362 biolink:BiologicalProcess negative regulation of molecular function in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044362 GO:0010945 biolink:MolecularActivity CoA pyrophosphatase activity Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine. Reactome:R-HSA-6809354|Reactome:R-HSA-6810474 go-plus.json conezyme A pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0010945 GO:0034916 biolink:MolecularActivity 2-methylhexanoyl-CoA dehydrogenase activity Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-. UM-BBD_reactionID:r0928|EC:1.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0034916 GO:0044363 biolink:BiologicalProcess modulation of potassium channel activity in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044363 GO:0010946 biolink:BiologicalProcess regulation of meiotic joint molecule formation Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. go-plus.json http://purl.obolibrary.org/obo/GO_0010946 GO:0034917 biolink:MolecularActivity 2-methylhex-2-enoyl-CoA hydratase activity Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA. UM-BBD_reactionID:r0929 go-plus.json http://purl.obolibrary.org/obo/GO_0034917 GO:0009950 biolink:BiologicalProcess dorsal/ventral axis specification The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. go-plus.json dorsoventral axis specification|dorsal-ventral axis specification|dorsal/ventral axis determination http://purl.obolibrary.org/obo/GO_0009950 GO:0009951 biolink:BiologicalProcess polarity specification of dorsal/ventral axis Any process resulting in the establishment of polarity along the dorsal/ventral axis. go-plus.json polarity specification of dorsoventral axis|polarity specification of dorsal-ventral axis http://purl.obolibrary.org/obo/GO_0009951 GO:0010940 biolink:BiologicalProcess positive regulation of necrotic cell death Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. go-plus.json http://purl.obolibrary.org/obo/GO_0010940 GO:0009952 biolink:BiologicalProcess anterior/posterior pattern specification The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. go-plus.json anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0009952 NCBITaxon:68297 biolink:OrganismalEntity Dictyoglomi go-plus.json Dictyoglomota|Dictyoglomus group|Dictyoglomaeota http://purl.obolibrary.org/obo/NCBITaxon_68297 GO:0009953 biolink:BiologicalProcess dorsal/ventral pattern formation The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. go-plus.json dorsal-ventral pattern formation|dorsal/ventral pattern specification|dorsoventral pattern formation http://purl.obolibrary.org/obo/GO_0009953 GO:0009954 biolink:BiologicalProcess proximal/distal pattern formation The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end). go-plus.json proximal/distal pattern specification http://purl.obolibrary.org/obo/GO_0009954 GO:0009955 biolink:BiologicalProcess adaxial/abaxial pattern specification The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure. go-plus.json adaxial/abaxial pattern formation http://purl.obolibrary.org/obo/GO_0009955 GO:0009956 biolink:BiologicalProcess radial pattern formation The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur. go-plus.json radial pattern specification http://purl.obolibrary.org/obo/GO_0009956 GO:0009957 biolink:BiologicalProcess epidermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json hypodermal cell fate specification http://purl.obolibrary.org/obo/GO_0009957 GO:0009958 biolink:BiologicalProcess positive gravitropism The orientation of plant parts towards gravity. go-plus.json root gravitropism http://purl.obolibrary.org/obo/GO_0009958 GO:0009959 biolink:BiologicalProcess negative gravitropism The orientation of plant parts away from gravity. go-plus.json shoot gravitropism http://purl.obolibrary.org/obo/GO_0009959 GO:0044371 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044371 GO:0034907 biolink:MolecularActivity acetanilide 1,2-dioxygenase activity Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide. UM-BBD_reactionID:r0723|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0034907 UBERON:0004709 biolink:AnatomicalEntity pelvic appendage Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues. go-plus.json hindlimb/pelvic fin|posterior paired appendage|pelvic appendage|posterior appendage|pelvic limb/fin|posterior limb/fin http://purl.obolibrary.org/obo/UBERON_0004709 GO:0044372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044372 GO:0034908 biolink:MolecularActivity 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+. UM-BBD_reactionID:r0724|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0034908 GO:0034909 biolink:MolecularActivity 6-hydroxypseudooxynicotine dehydrogenase activity Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine. EC:1.5.99.14|UM-BBD_reactionID:r1441|RHEA:34223 go-plus.json http://purl.obolibrary.org/obo/GO_0034909 UBERON:0004707 biolink:AnatomicalEntity pharyngula stage A stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities. go-plus.json phylotypic stage|pharyngula http://purl.obolibrary.org/obo/UBERON_0004707 GO:0044370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044370 UBERON:0004708 biolink:AnatomicalEntity paired limb/fin An appendage that is part of an appendage girdle complex. go-plus.json girdle-associated appendage|paired appendage|limb or fin|jointed paired lateral appendage|pelvic/pectoral appendage|pectoral or pelvic appendage|limb/fin http://purl.obolibrary.org/obo/UBERON_0004708 UBERON:0004706 biolink:AnatomicalEntity bulbus cordis a transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches go-plus.json primitive right ventricle endocardium http://purl.obolibrary.org/obo/UBERON_0004706 UBERON:0004703 biolink:AnatomicalEntity dorsal thalamus go-plus.json thalamus proper|dorsal thalamus (Anthoney)|dorsal tier of thalamus|thalamus dorsalis|dorsal thalamus|thalamus, pars dorsalis http://purl.obolibrary.org/obo/UBERON_0004703 CHEBI:47537 biolink:ChemicalSubstance L-glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_47537 UBERON:0004704 biolink:AnatomicalEntity bone fossa A depression or hollow in a bone[WP]. go-plus.json fossae|depressions|depression|groove|concavity|concavities|fossa http://purl.obolibrary.org/obo/UBERON_0004704 GO:0010954 biolink:BiologicalProcess positive regulation of protein processing Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage. go-plus.json positive regulation of protein maturation by peptide bond cleavage http://purl.obolibrary.org/obo/GO_0010954 GO:0044379 biolink:BiologicalProcess protein localization to actin cortical patch A process in which a protein is transported to, or maintained in, an actin cortical patch. go-plus.json protein localisation to actin cortical patch http://purl.obolibrary.org/obo/GO_0044379 GO:0010955 biolink:BiologicalProcess negative regulation of protein processing Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage. go-plus.json negative regulation of protein maturation by peptide bond cleavage http://purl.obolibrary.org/obo/GO_0010955 GO:0034900 biolink:MolecularActivity 3-(N-formyl)-formiminopyruvate hydrolase activity Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate. EC:3.5.99.-|UM-BBD_reactionID:r1399 go-plus.json http://purl.obolibrary.org/obo/GO_0034900 GO:0044377 biolink:MolecularActivity RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. go-plus.json RNA polymerase II proximal promoter sequence-specific DNA binding, bending|RNA polymerase II proximal promoter region sequence-specific DNA binding, bending|RNA polymerase II promoter proximal region sequence-specific DNA binding, bending|RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending http://purl.obolibrary.org/obo/GO_0044377 GO:0010952 biolink:BiologicalProcess positive regulation of peptidase activity Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010952 GO:0034901 biolink:MolecularActivity endosulfan hydroxyether dehydrogenase activity Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-. UM-BBD_reactionID:r1411 go-plus.json http://purl.obolibrary.org/obo/GO_0034901 GO:0044378 biolink:MolecularActivity non-sequence-specific DNA binding, bending The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. go-plus.json DNA bending involving non-sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0044378 GO:0010953 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010953 GO:0034902 biolink:MolecularActivity endosulfan sulfate hydrolase activity Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite. UM-BBD_reactionID:r1387 go-plus.json http://purl.obolibrary.org/obo/GO_0034902 GO:0010958 biolink:BiologicalProcess regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of amino acid import into a cell. go-plus.json regulation of amino acid import http://purl.obolibrary.org/obo/GO_0010958 GO:0034903 biolink:MolecularActivity endosulfan ether monooxygenase activity Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O. UM-BBD_reactionID:r1413 go-plus.json http://purl.obolibrary.org/obo/GO_0034903 GO:0044375 biolink:BiologicalProcess regulation of peroxisome size Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0044375 CHEBI:23582 biolink:ChemicalSubstance defoliant go-plus.json http://purl.obolibrary.org/obo/CHEBI_23582 GO:0044376 biolink:BiologicalProcess obsolete RNA polymerase II complex import to nucleus OBSOLETE. The directed movement of the DNA-directed RNA polymerase II core complex from the cytoplasm into the nucleus. go-plus.json DNA-directed RNA polymerase II core complex localization to nucleus|DNA-directed RNA polymerase II core complex import into nucleus|RNA polymerase II complex import into nucleus|RNA polymerase II complex localisation to nucleus http://purl.obolibrary.org/obo/GO_0044376 GO:0010959 biolink:BiologicalProcess regulation of metal ion transport Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0010959 GO:0034904 biolink:MolecularActivity 5-chloro-2-oxopent-4-enoate hydratase activity Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate. UM-BBD_reactionID:r1436 go-plus.json http://purl.obolibrary.org/obo/GO_0034904 GO:0034905 biolink:MolecularActivity 5-chloro-4-hydroxy-2-oxopentanate aldolase activity Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde. EC:4.1.3.-|UM-BBD_reactionID:r1437 go-plus.json http://purl.obolibrary.org/obo/GO_0034905 GO:0044373 biolink:MolecularActivity cytokinin binding Binding to a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0044373 GO:0010956 biolink:BiologicalProcess negative regulation of calcidiol 1-monooxygenase activity Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0010956 GO:0034906 biolink:MolecularActivity N-isopropylaniline 1,2-dixoxygenase activity Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine. EC:1.14.12.-|UM-BBD_reactionID:r0721 go-plus.json http://purl.obolibrary.org/obo/GO_0034906 GO:0044374 biolink:MolecularActivity sequence-specific DNA binding, bending The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. go-plus.json DNA bending involving sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_0044374 GO:0010957 biolink:BiologicalProcess negative regulation of vitamin D biosynthetic process Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json http://purl.obolibrary.org/obo/GO_0010957 GO:0009960 biolink:BiologicalProcess endosperm development The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0009960 GO:0010950 biolink:BiologicalProcess positive regulation of endopeptidase activity Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010950 GO:0009961 biolink:BiologicalProcess response to 1-aminocyclopropane-1-carboxylic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0009961 GO:0009962 biolink:BiologicalProcess regulation of flavonoid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. go-plus.json regulation of flavonoid biosynthesis|regulation of flavonoid formation|regulation of flavonoid anabolism|regulation of flavonoid synthesis http://purl.obolibrary.org/obo/GO_0009962 GO:0010951 biolink:BiologicalProcess negative regulation of endopeptidase activity Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0010951 goslim_chembl GO:0009963 biolink:BiologicalProcess positive regulation of flavonoid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. go-plus.json positive regulation of flavonoid anabolism|upregulation of flavonoid biosynthetic process|positive regulation of flavonoid synthesis|positive regulation of flavonoid formation|stimulation of flavonoid biosynthetic process|up-regulation of flavonoid biosynthetic process|activation of flavonoid biosynthetic process|positive regulation of flavonoid biosynthesis|up regulation of flavonoid biosynthetic process http://purl.obolibrary.org/obo/GO_0009963 GO:0009964 biolink:BiologicalProcess negative regulation of flavonoid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. go-plus.json down regulation of flavonoid biosynthetic process|inhibition of flavonoid biosynthetic process|negative regulation of flavonoid anabolism|negative regulation of flavonoid synthesis|negative regulation of flavonoid formation|down-regulation of flavonoid biosynthetic process|negative regulation of flavonoid biosynthesis|downregulation of flavonoid biosynthetic process http://purl.obolibrary.org/obo/GO_0009964 GO:0009965 biolink:BiologicalProcess leaf morphogenesis The process in which the anatomical structures of the leaf are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0009965 GO:0009966 biolink:BiologicalProcess regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction. go-plus.json regulation of signaling pathway|regulation of signalling pathway http://purl.obolibrary.org/obo/GO_0009966 GO:0009967 biolink:BiologicalProcess positive regulation of signal transduction Any process that activates or increases the frequency, rate or extent of signal transduction. go-plus.json up-regulation of signal transduction|upregulation of signal transduction|positive regulation of signaling pathway|up regulation of signal transduction|activation of signal transduction|positive regulation of signalling pathway|stimulation of signal transduction http://purl.obolibrary.org/obo/GO_0009967 UBERON:0004710 biolink:AnatomicalEntity pectoral appendage Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues. go-plus.json anterior appendage|forelimb or pectoral fin|anterior paired appendage|forelimb - pectoral fin|forelimb/pectoral fin|pectoral limb/fin|anterior limb/fin http://purl.obolibrary.org/obo/UBERON_0004710 GO:0009968 biolink:BiologicalProcess negative regulation of signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. go-plus.json inhibition of signal transduction|down regulation of signal transduction|negative regulation of signaling pathway|downregulation of signal transduction|negative regulation of signalling pathway|down-regulation of signal transduction http://purl.obolibrary.org/obo/GO_0009968 UBERON:0004711 biolink:AnatomicalEntity jugular vein The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava. go-plus.json vena jugularis|jugular http://purl.obolibrary.org/obo/UBERON_0004711 GO:0009969 biolink:BiologicalProcess xyloglucan biosynthetic process The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants. go-plus.json xyloglucan biosynthesis|xyloglucan anabolism|xyloglucan synthesis|xyloglucan formation http://purl.obolibrary.org/obo/GO_0009969 CHEBI:140278 biolink:ChemicalSubstance 5-hydroxyanthocyanin O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_140278 chebi_ph7_3 CHEBI:140276 biolink:ChemicalSubstance 21-phosphorifampicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140276 CHEBI:140277 biolink:ChemicalSubstance 5-hydroxyanthocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140277 chebi_ph7_3 CHEBI:140275 biolink:ChemicalSubstance 2alpha,3alpha-dihydroxy-ent-isokaurene go-plus.json http://purl.obolibrary.org/obo/CHEBI_140275 chebi_ph7_3 CHEBI:139278 biolink:ChemicalSubstance calcidiol 3-O-(beta-D-glucuronate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139278 chebi_ph7_3 CHEBI:139274 biolink:ChemicalSubstance calcitriol 25-O-(beta-D-glucuronate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139274 chebi_ph7_3 CHEBI:139277 biolink:ChemicalSubstance calcidiol 25-O-(beta-D-glucuronate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139277 chebi_ph7_3 CHEBI:139292 biolink:ChemicalSubstance chlorophyllide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139292 chebi_ph7_3 CHEBI:140260 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140260 chebi_ph7_3 CHEBI:139291 biolink:ChemicalSubstance chlorophyll(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139291 chebi_ph7_3 PR:000008630 biolink:Protein high mobility group protein B1 A protein that is a translation product of the human HMGB1 gene or a 1:1 ortholog thereof. go-plus.json high mobility group protein 1|HMGB1|HMG1|HMG-1 http://purl.obolibrary.org/obo/PR_000008630 CHEBI:139289 biolink:ChemicalSubstance [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139289 chebi_ph7_3 CHEBI:139285 biolink:ChemicalSubstance [(2->8)-N,O(7)-diacetyl-alpha-D-neuraminosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139285 chebi_ph7_3 CHEBI:139286 biolink:ChemicalSubstance [(2->8)-N,O(9)-diacetyl-alpha-D-neuraminosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139286 chebi_ph7_3 CHEBI:139287 biolink:ChemicalSubstance [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139287 chebi_ph7_3 CHEBI:139288 biolink:ChemicalSubstance [(2->6)-alpha-D-glucosyl-(1->4)-N,O(7)-diacetyl-alpha-D-neuraminosyl]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139288 chebi_ph7_3 NCBITaxon:213849 biolink:OrganismalEntity Campylobacterales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_213849 CHEBI:140259 biolink:ChemicalSubstance sordaricin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140259 CHEBI:139258 biolink:ChemicalSubstance all-trans-18-hydroxyretinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139258 chebi_ph7_3 GO:0019399 biolink:BiologicalProcess cyclohexanol oxidation The cyclohexanol metabolic process in which cyclohexanol is converted to adipate. MetaCyc:CYCLOHEXANOL-OXIDATION-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019399 GO:0019397 biolink:BiologicalProcess gallate catabolic process via 2-pyrone-4,6-dicarboxylate The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate. MetaCyc:GALLATE-DEGRADATION-I-PWY go-plus.json gallate breakdown via 2-pyrone-4,6-dicarboxylate|gallate degradation via 2-pyrone-4,6-dicarboxylate|gallic acid catabolic process via 2-pyrone-4,6-dicarboxylate|gallic acid catabolism via 2-pyrone-4,6-dicarboxylate http://purl.obolibrary.org/obo/GO_0019397 CHEBI:139252 biolink:ChemicalSubstance [8)-alpha-Neu5Ac-(2->]n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_139252 chebi_ph7_3 GO:0019398 biolink:BiologicalProcess gallate catabolic process via gallate dioxygenase activity The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase. MetaCyc:GALLATE-DEGRADATION-II-PWY go-plus.json gallate degradation via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolism via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate breakdown via 4-carboxy-2-hydroxhexa-2,3-dienedioate http://purl.obolibrary.org/obo/GO_0019398 GO:0019395 biolink:BiologicalProcess fatty acid oxidation The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. MetaCyc:FAO-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019395 GO:0019396 biolink:BiologicalProcess gallate catabolic process The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). UM-BBD_pathwayID:gal go-plus.json gallate degradation|gallic acid metabolism|gallate breakdown|gallate catabolism|gallate metabolic process|gallate metabolism|gallic acid metabolic process|gallic acid catabolism|gallic acid catabolic process http://purl.obolibrary.org/obo/GO_0019396 CHEBI:139270 biolink:ChemicalSubstance (S)-3-hydroxypentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139270 CHEBI:139271 biolink:ChemicalSubstance 6beta-hydroxycortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_139271 chebi_ph7_3 CHEBI:139272 biolink:ChemicalSubstance 3-hydroxypentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139272 CHEBI:139273 biolink:ChemicalSubstance 4-O-methylxanthohumol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139273 chebi_ph7_3 CHEBI:72513 biolink:ChemicalSubstance sphingomyelin 34:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72513 chebi_ph7_3 CHEBI:72514 biolink:ChemicalSubstance sphingomyelin 34:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72514 chebi_ph7_3 CHEBI:72518 biolink:ChemicalSubstance sphingomyelin 36:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72518 chebi_ph7_3 CHEBI:140241 biolink:ChemicalSubstance 3-bromo-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140241 CHEBI:140242 biolink:ChemicalSubstance 3-bromo-4,5-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_140242 CHEBI:139267 biolink:ChemicalSubstance [(3S)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139267 CHEBI:139268 biolink:ChemicalSubstance (S)-3-hydroxypentanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139268 CHEBI:139269 biolink:ChemicalSubstance 6beta-hydroxycortisone go-plus.json http://purl.obolibrary.org/obo/CHEBI_139269 chebi_ph7_3 GO:0019382 biolink:BiologicalProcess carbon tetrachloride catabolic process The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants. go-plus.json carbon tetrachloride degradation|carbon tetrachloride breakdown|carbon tetrachloride catabolism http://purl.obolibrary.org/obo/GO_0019382 GO:0019383 biolink:BiologicalProcess (+)-camphor catabolic process The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone. MetaCyc:P601-PWY go-plus.json (+)-camphor catabolism|(+)-camphor degradation|(+)-camphor breakdown http://purl.obolibrary.org/obo/GO_0019383 GO:0019380 biolink:BiologicalProcess 3-phenylpropionate catabolic process The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid. MetaCyc:HCAMHPDEG-PWY|MetaCyc:P281-PWY go-plus.json 3-phenylpropionate degradation|3-phenylpropionate breakdown|3-phenylpropionate catabolism http://purl.obolibrary.org/obo/GO_0019380 GO:0019381 biolink:BiologicalProcess atrazine catabolic process The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide. MetaCyc:P141-PWY go-plus.json atrazine degradation|atrazine breakdown|atrazine catabolism http://purl.obolibrary.org/obo/GO_0019381 CHEBI:139240 biolink:ChemicalSubstance 7(1)-hydroxybacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139240 chebi_ph7_3 CHEBI:140232 biolink:ChemicalSubstance sordaricin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140232 chebi_ph7_3 CHEBI:140233 biolink:ChemicalSubstance 4'-O-demethylsordarin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140233 chebi_ph7_3 CHEBI:139239 biolink:ChemicalSubstance (R)-3-hydroxypentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139239 GO:0019379 biolink:BiologicalProcess sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8). MetaCyc:SO4ASSIM-PWY go-plus.json sulphate assimilation, phosphoadenylyl sulphate reduction by a phosphoadenylyl-sulphate reductase (thioredoxin) http://purl.obolibrary.org/obo/GO_0019379 CHEBI:139235 biolink:ChemicalSubstance (3E,5Z)-dodecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139235 GO:0019377 biolink:BiologicalProcess glycolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). go-plus.json glycolipid catabolism|glycolipid degradation|glycolipid breakdown http://purl.obolibrary.org/obo/GO_0019377 CHEBI:139236 biolink:ChemicalSubstance (R)-3-hydroxypentanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_139236 GO:0019378 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0019378 CHEBI:139237 biolink:ChemicalSubstance bacteriochlorophyllide f(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139237 chebi_ph7_3 GO:0019375 biolink:BiologicalProcess galactolipid biosynthetic process The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. go-plus.json galactolipid anabolism|galactolipid synthesis|galactolipid formation|galactolipid biosynthesis http://purl.obolibrary.org/obo/GO_0019375 CHEBI:139230 biolink:ChemicalSubstance (R,R)-2-oleoylglycero-1-phospho-1'-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139230 chebi_ph7_3 GO:0019376 biolink:BiologicalProcess galactolipid catabolic process The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. go-plus.json galactolipid breakdown|galactolipid catabolism|galactolipid degradation http://purl.obolibrary.org/obo/GO_0019376 CHEBI:139231 biolink:ChemicalSubstance 5-methyldeoxycytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_139231 GO:0019373 biolink:BiologicalProcess epoxygenase P450 pathway The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0019373 GO:0019374 biolink:BiologicalProcess galactolipid metabolic process The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. go-plus.json galactolipid metabolism http://purl.obolibrary.org/obo/GO_0019374 GO:0019393 biolink:BiologicalProcess glucarate biosynthetic process The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid. go-plus.json glucarate biosynthesis|glucarate anabolism|glucarate synthesis|glucarate formation http://purl.obolibrary.org/obo/GO_0019393 GO:0019394 biolink:BiologicalProcess glucarate catabolic process The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid. MetaCyc:GLUCARDEG-PWY go-plus.json glucarate degradation|glucarate breakdown|glucarate catabolism http://purl.obolibrary.org/obo/GO_0019394 GO:0019391 biolink:BiologicalProcess glucuronoside catabolic process The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue. MetaCyc:GLUCUROCAT-PWY go-plus.json glucuronoside degradation|glucuronoside breakdown|glucuronoside catabolism|glucuronide catabolic process|glucuronide catabolism http://purl.obolibrary.org/obo/GO_0019391 CHEBI:72533 biolink:ChemicalSubstance sphingomyelin 42:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72533 chebi_ph7_3 GO:0019392 biolink:BiologicalProcess glucarate metabolic process The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate. go-plus.json glucarate metabolism http://purl.obolibrary.org/obo/GO_0019392 CHEBI:72534 biolink:ChemicalSubstance sphingomyelin 42:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_72534 chebi_ph7_3 GO:0019390 biolink:BiologicalProcess glucuronoside biosynthetic process The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue. go-plus.json glucuronoside biosynthesis|glucuronide biosynthetic process|glucuronide biosynthesis|glucuronoside anabolism|glucuronoside synthesis|glucuronoside formation http://purl.obolibrary.org/obo/GO_0019390 CHEBI:140221 biolink:ChemicalSubstance O-[S-(5-chloropyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140221 chebi_ph7_3 GO:0019388 biolink:BiologicalProcess galactose catabolic process The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose. MetaCyc:GALDEG-PWY go-plus.json galactose catabolism|galactose degradation|galactose breakdown http://purl.obolibrary.org/obo/GO_0019388 GO:0019389 biolink:BiologicalProcess glucuronoside metabolic process The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate. go-plus.json glucuronoside metabolism|glucuronide metabolism|glucuronide metabolic process http://purl.obolibrary.org/obo/GO_0019389 CHEBI:139248 biolink:ChemicalSubstance [4-(6-methylheptanoyl)-5-oxo-2,5-dihydrofuran-3-yl]methyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_139248 GO:0019386 biolink:BiologicalProcess methanogenesis, from carbon dioxide The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2). MetaCyc:METHANOGENESIS-PWY go-plus.json methane biosynthesis from carbon dioxide|methane biosynthetic process from carbon dioxide http://purl.obolibrary.org/obo/GO_0019386 GO:0019387 biolink:BiologicalProcess methanogenesis, from methanol The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol. MetaCyc:METHFORM-PWY go-plus.json methane biosynthesis from methanol|methane biosynthetic process from methanol http://purl.obolibrary.org/obo/GO_0019387 CHEBI:139242 biolink:ChemicalSubstance 7(1),7(1)-dihydroxybacteriochlorophyllide d(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139242 chebi_ph7_3 GO:0019384 biolink:BiologicalProcess caprolactam catabolic process The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid. MetaCyc:P621-PWY go-plus.json caprolactam catabolism|caprolactam degradation|caprolactam breakdown http://purl.obolibrary.org/obo/GO_0019384 GO:0019385 biolink:BiologicalProcess methanogenesis, from acetate The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate. MetaCyc:METH-ACETATE-PWY go-plus.json methane biosynthetic process from acetate|methane biosynthesis from acetate http://purl.obolibrary.org/obo/GO_0019385 GO:0019360 biolink:BiologicalProcess nicotinamide nucleotide biosynthetic process from niacinamide The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide. go-plus.json nicotinamide nucleotide formation from niacinamide|nicotinamide nucleotide synthesis from niacinamide|nicotinamide nucleotide anabolism from niacinamide http://purl.obolibrary.org/obo/GO_0019360 GO:0019361 biolink:BiologicalProcess 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A. MetaCyc:P2-PWY go-plus.json 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA anabolism|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA synthesis|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA formation|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthesis http://purl.obolibrary.org/obo/GO_0019361 CHEBI:72544 biolink:ChemicalSubstance flavonoids go-plus.json http://purl.obolibrary.org/obo/CHEBI_72544 GO:0034998 biolink:CellularComponent oligosaccharyltransferase I complex An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes. go-plus.json OSTCI http://purl.obolibrary.org/obo/GO_0034998 GO:0034999 biolink:CellularComponent oligosaccharyltransferase II complex An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes. go-plus.json OSTCII http://purl.obolibrary.org/obo/GO_0034999 CHEBI:140211 biolink:ChemicalSubstance 3-bromo-4,5-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140211 chebi_ph7_3 PR:000008636 biolink:Protein 3-hydroxy-3-methylglutaryl-coenzyme A reductase A protein that is a translation product of the human HMGCR gene or a 1:1 ortholog thereof. go-plus.json HMGCR|HMG-CoA reductase http://purl.obolibrary.org/obo/PR_000008636 GO:0034990 biolink:CellularComponent nuclear mitotic cohesin complex A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034990 GO:0034991 biolink:CellularComponent nuclear meiotic cohesin complex A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0034991 GO:0034992 biolink:CellularComponent microtubule organizing center attachment site A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope. go-plus.json microtubule organising centre attachment site|MAS|MTOC attachment site http://purl.obolibrary.org/obo/GO_0034992 GO:0034993 biolink:CellularComponent meiotic nuclear membrane microtubule tethering complex A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis. go-plus.json SUN-KASH complex|LINC complex|LInker of Nucleoskeleton and Cytoskeleton complex http://purl.obolibrary.org/obo/GO_0034993 CHEBI:140219 biolink:ChemicalSubstance O-[S-(4,5-dichloropyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140219 chebi_ph7_3 GO:0034994 biolink:BiologicalProcess microtubule organizing center attachment site organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches. go-plus.json MTOC attachment site organization|MAS organization|microtubule organising centre attachment site organisation http://purl.obolibrary.org/obo/GO_0034994 GO:0034995 biolink:CellularComponent SC5b-7 complex A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0034995 CHEBI:139217 biolink:ChemicalSubstance 4-hydroxytryptamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_139217 GO:0019359 biolink:BiologicalProcess nicotinamide nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide. go-plus.json nicotinamide nucleotide biosynthesis|nicotinamide nucleotide anabolism|nicotinamide nucleotide synthesis|nicotinamide nucleotide formation http://purl.obolibrary.org/obo/GO_0019359 CHEBI:139218 biolink:ChemicalSubstance secondary nitroalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_139218 chebi_ph7_3 GO:0034996 biolink:CellularComponent RasGAP-Fyn-Lyn-Yes complex A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation. go-plus.json p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated http://purl.obolibrary.org/obo/GO_0034996 CHEBI:140214 biolink:ChemicalSubstance 3,5-dibromocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_140214 chebi_ph7_3 GO:0034997 biolink:CellularComponent alphav-beta5 integrin-vitronectin complex A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin. go-plus.json ITGAV-ITGB5-VTN complex http://purl.obolibrary.org/obo/GO_0034997 GO:0019357 biolink:BiologicalProcess nicotinate nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid). go-plus.json nicotinate nucleotide synthesis|nicotinate nucleotide formation|nicotinate nucleotide biosynthesis|nicotinate nucleotide anabolism http://purl.obolibrary.org/obo/GO_0019357 GO:0019358 biolink:BiologicalProcess nicotinate nucleotide salvage The generation of nicotinate nucleotide without de novo synthesis. MetaCyc:PWY-5381|MetaCyc:PYRIDNUCSAL-PWY go-plus.json nicotinate nucleotide biosynthetic process, salvage pathway|nicotinate nucleotide biosynthesis, salvage pathway http://purl.obolibrary.org/obo/GO_0019358 GO:0019355 biolink:BiologicalProcess nicotinamide nucleotide biosynthetic process from aspartate The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate. go-plus.json nicotinamide nucleotide formation from aspartate|nicotinamide nucleotide synthesis from aspartate|nicotinamide nucleotide anabolism from aspartate http://purl.obolibrary.org/obo/GO_0019355 GO:0019356 biolink:BiologicalProcess nicotinate nucleotide biosynthetic process from tryptophan The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan. go-plus.json nicotinate nucleotide anabolism from tryptophan|nicotinate nucleotide synthesis from tryptophan|nicotinate nucleotide formation from tryptophan http://purl.obolibrary.org/obo/GO_0019356 CHEBI:139215 biolink:ChemicalSubstance cochalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_139215 GO:0019353 biolink:BiologicalProcess protoporphyrinogen IX biosynthetic process from glutamate The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate. go-plus.json protoporphyrinogen IX formation from glutamate|protoporphyrinogen IX synthesis from glutamate|protoporphyrinogen IX anabolism from glutamate http://purl.obolibrary.org/obo/GO_0019353 GO:0019354 biolink:BiologicalProcess siroheme biosynthetic process The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings. MetaCyc:PWY-5194 go-plus.json siroheme biosynthesis|siroheme anabolism|siroheme synthesis|siroheme synthase activity|siroheme formation|sirohaem biosynthesis|sirohaem biosynthetic process http://purl.obolibrary.org/obo/GO_0019354 GO:0019351 biolink:BiologicalProcess dethiobiotin biosynthetic process The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms. go-plus.json dethiobiotin anabolism|dethiobiotin synthesis|dethiobiotin biosynthesis|dethiobiotin formation|desthiobiotin biosynthetic process|desthiobiotin biosynthesis http://purl.obolibrary.org/obo/GO_0019351 GO:0019352 biolink:BiologicalProcess protoporphyrinogen IX biosynthetic process from glycine The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine. go-plus.json protoporphyrinogen IX formation from glycine|protoporphyrinogen IX synthesis from glycine|protoporphyrinogen IX anabolism from glycine http://purl.obolibrary.org/obo/GO_0019352 GO:0019371 biolink:BiologicalProcess cyclooxygenase pathway The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2. go-plus.json http://purl.obolibrary.org/obo/GO_0019371 GO:0019372 biolink:BiologicalProcess lipoxygenase pathway The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase. go-plus.json http://purl.obolibrary.org/obo/GO_0019372 GO:0019370 biolink:BiologicalProcess leukotriene biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. Wikipedia:Leukotriene#Leukotriene_synthesis go-plus.json leukotriene biosynthesis|leukotriene anabolism|leukotriene synthesis|leukotriene formation http://purl.obolibrary.org/obo/GO_0019370 GO:0034987 biolink:MolecularActivity immunoglobulin receptor binding Binding to one or more specific sites on an immunoglobulin receptor molecule. go-plus.json Fc receptor binding http://purl.obolibrary.org/obo/GO_0034987 GO:0034988 biolink:MolecularActivity Fc-gamma receptor I complex binding Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG. go-plus.json http://purl.obolibrary.org/obo/GO_0034988 GO:0034989 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034989 GO:0034980 biolink:CellularComponent FHL2-CREB complex A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation. go-plus.json http://purl.obolibrary.org/obo/GO_0034980 GO:0034981 biolink:CellularComponent FHL3-CREB complex A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation. go-plus.json http://purl.obolibrary.org/obo/GO_0034981 GO:0034982 biolink:BiologicalProcess mitochondrial protein processing The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. go-plus.json mitochondrial protein modification http://purl.obolibrary.org/obo/GO_0034982 GO:0034983 biolink:BiologicalProcess peptidyl-lysine deacetylation The removal of an acetyl group from an acetylated lysine residue in a peptide or protein. go-plus.json protein lysine acetylation http://purl.obolibrary.org/obo/GO_0034983 GO:0034984 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034984 CHEBI:139228 biolink:ChemicalSubstance (R,R)-bis(2-oleoylglycero)-3-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_139228 chebi_ph7_3 GO:0034985 biolink:CellularComponent Ecsit-NDUFAF1 complex Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed. go-plus.json http://purl.obolibrary.org/obo/GO_0034985 CHEBI:140203 biolink:ChemicalSubstance 3-bromo-4-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_140203 chebi_ph7_3 GO:0034986 biolink:MolecularActivity iron chaperone activity Directly binding to and delivering iron ions to a target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0034986 GO:0019368 biolink:BiologicalProcess fatty acid elongation, unsaturated fatty acid Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced. MetaCyc:PWY0-862 go-plus.json http://purl.obolibrary.org/obo/GO_0019368 GO:0019369 biolink:BiologicalProcess arachidonic acid metabolic process The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. Wikipedia:Arachidonic_acid go-plus.json arachidonic acid metabolism http://purl.obolibrary.org/obo/GO_0019369 GO:0019367 biolink:BiologicalProcess fatty acid elongation, saturated fatty acid Elongation of a saturated fatty acid chain. MetaCyc:FASYN-ELONG-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0019367 GO:0019364 biolink:BiologicalProcess pyridine nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. go-plus.json pyridine nucleotide catabolism|pyridine nucleotide degradation|pyridine nucleotide breakdown http://purl.obolibrary.org/obo/GO_0019364 GO:0019365 biolink:BiologicalProcess pyridine nucleotide salvage Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis. go-plus.json pyridine nucleotide cycling http://purl.obolibrary.org/obo/GO_0019365 GO:0019362 biolink:BiologicalProcess pyridine nucleotide metabolic process The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. go-plus.json pyridine nucleotide metabolism http://purl.obolibrary.org/obo/GO_0019362 GO:0019363 biolink:BiologicalProcess pyridine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. MetaCyc:PYRIDNUCSYN-PWY go-plus.json pyridine nucleotide anabolism|pyridine nucleotide synthesis|pyridine nucleotide formation|pyridine nucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0019363 GO:0103041 biolink:MolecularActivity thiosulfate-thioredoxin sulfurtransferase activity Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin. MetaCyc:RXN0-6385 go-plus.json http://purl.obolibrary.org/obo/GO_0103041 GO:0103042 biolink:MolecularActivity 4-hydroxy-L-threonine aldolase activity Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine. MetaCyc:RXN0-6563|RHEA:28779 go-plus.json http://purl.obolibrary.org/obo/GO_0103042 GO:0103040 biolink:MolecularActivity aldose sugar dehydrogenase activity Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor. MetaCyc:RXN0-6371 go-plus.json http://purl.obolibrary.org/obo/GO_0103040 GO:0103045 biolink:MolecularActivity methione N-acyltransferase activity Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+. RHEA:44144|EC:2.3.1.1|MetaCyc:RXN0-6948 go-plus.json http://purl.obolibrary.org/obo/GO_0103045 GO:0103046 biolink:MolecularActivity alanylglutamate dipeptidase activity Catalysis of the reaction: L-alanyl-L-glutamate + H2O <=> L-alanine + L-glutamate. MetaCyc:RXN0-6981|EC:3.4.13.18 go-plus.json http://purl.obolibrary.org/obo/GO_0103046 GO:0103043 biolink:MolecularActivity 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate. MetaCyc:RXN0-6710|EC:3.1.4.55|RHEA:34795 go-plus.json http://purl.obolibrary.org/obo/GO_0103043 GO:0103044 biolink:MolecularActivity ribosomal protein S6 glutamate-glutamate ligase activity Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate. MetaCyc:RXN0-6726 go-plus.json http://purl.obolibrary.org/obo/GO_0103044 GO:0103047 biolink:MolecularActivity methyl beta-D-glucoside 6-phosphate glucohydrolase activity Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol. MetaCyc:RXN0-6994|EC:3.2.1.86 go-plus.json http://purl.obolibrary.org/obo/GO_0103047 GO:0103048 biolink:MolecularActivity tRNA m2A37 methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + an adenine37 in tRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA. MetaCyc:RXN0-7007 go-plus.json http://purl.obolibrary.org/obo/GO_0103048 GO:0103052 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103052 GO:0103053 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103053 GO:0103050 biolink:MolecularActivity isobutyraldehyde reductase activity Catalysis of the reaction: isobutanol + NADP <=> isobutyraldehyde + NADPH + H+. MetaCyc:RXN0-7119 go-plus.json http://purl.obolibrary.org/obo/GO_0103050 GO:0103051 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103051 GO:0103056 biolink:MolecularActivity gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate. RHEA:60800|MetaCyc:RXN1F-167 go-plus.json http://purl.obolibrary.org/obo/GO_0103056 GO:0103057 biolink:MolecularActivity gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate. MetaCyc:RXN1F-169 go-plus.json http://purl.obolibrary.org/obo/GO_0103057 GO:0103054 biolink:MolecularActivity gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming) Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate. RHEA:60776|MetaCyc:RXN1F-162 go-plus.json http://purl.obolibrary.org/obo/GO_0103054 GO:0103055 biolink:MolecularActivity gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O. RHEA:60780|MetaCyc:RXN1F-163 go-plus.json http://purl.obolibrary.org/obo/GO_0103055 GO:0103058 biolink:MolecularActivity kaempferol 3-glucoside 7-O-rhamnosyltransferase activity Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP. MetaCyc:RXN1F-443 go-plus.json http://purl.obolibrary.org/obo/GO_0103058 GO:0103059 biolink:MolecularActivity UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-). MetaCyc:RXN1F-474|RHEA:61164 go-plus.json http://purl.obolibrary.org/obo/GO_0103059 GO:0103060 biolink:MolecularActivity kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP. MetaCyc:RXN1F-475 go-plus.json http://purl.obolibrary.org/obo/GO_0103060 GO:0103063 biolink:MolecularActivity trans-keto-C61-meroacyl-AMP ligase activity Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]. MetaCyc:RXN1G-4143 go-plus.json http://purl.obolibrary.org/obo/GO_0103063 GO:0103064 biolink:MolecularActivity inositol phosphorylceramide mannosyltransferase activity Catalysis of the reaction: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1,6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H+. EC:2.4.1.370|MetaCyc:RXN3O-663|https://github.com/geneontology/go-ontology/issues/21803|RHEA:64596 go-plus.json http://purl.obolibrary.org/obo/GO_0103064 GO:0103061 biolink:MolecularActivity trans-methoxy-C60-meroacyl-AMP ligase activity Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein]. MetaCyc:RXN1G-4141 go-plus.json http://purl.obolibrary.org/obo/GO_0103061 GO:0103062 biolink:MolecularActivity cis-keto-C60-meroacyl-AMP ligase activity Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]. MetaCyc:RXN1G-4142 go-plus.json http://purl.obolibrary.org/obo/GO_0103062 GO:0103067 biolink:MolecularActivity 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H. RHEA:33447|MetaCyc:RXN66-23|EC:1.1.1.170 go-plus.json http://purl.obolibrary.org/obo/GO_0103067 GO:0103068 biolink:MolecularActivity leukotriene C4 gamma-glutamyl transferase activity Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid. EC:2.3.2.2|MetaCyc:RXN66-336 go-plus.json http://purl.obolibrary.org/obo/GO_0103068 GO:0103066 biolink:MolecularActivity 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H. MetaCyc:RXN66-18|EC:1.1.1.170 go-plus.json http://purl.obolibrary.org/obo/GO_0103066 GO:0103069 biolink:MolecularActivity 17-hydroxyprogesterone 21-hydroxylase activity Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. MetaCyc:RXN66-356|RHEA:50308 go-plus.json http://purl.obolibrary.org/obo/GO_0103069 GO:0103071 biolink:MolecularActivity 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA lyase activity Catalysis of the reaction: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA <=> formyl-CoA + a 2-methyl branched 2,3,4-saturated fatty aldehyde. MetaCyc:RXN66-471 go-plus.json http://purl.obolibrary.org/obo/GO_0103071 GO:0103074 biolink:MolecularActivity glucose-6-phosphate 3-dehydrogenase activity Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate. EC:1.1.1.361|MetaCyc:RXN8J2-136|RHEA:37547 go-plus.json http://purl.obolibrary.org/obo/GO_0103074 GO:0103075 biolink:MolecularActivity indole-3-pyruvate monooxygenase activity Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O. EC:1.14.13.168|RHEA:34331|MetaCyc:RXNDQC-2 go-plus.json http://purl.obolibrary.org/obo/GO_0103075 GO:0103072 biolink:MolecularActivity straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde. MetaCyc:RXN66-475 go-plus.json http://purl.obolibrary.org/obo/GO_0103072 GO:0103073 biolink:MolecularActivity anandamide amidohydrolase activity Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+). MetaCyc:RXN6666-2|EC:3.5.1.99|RHEA:26136 go-plus.json http://purl.obolibrary.org/obo/GO_0103073 GO:0103078 biolink:MolecularActivity quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP. MetaCyc:RXNQT-4162|RHEA:61184 go-plus.json http://purl.obolibrary.org/obo/GO_0103078 GO:0103079 biolink:MolecularActivity 2-(3'-methylthio)propylmalate synthase activity Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA + H2O <=> H+ + 2-(3-methylthiopropyl)malate + coenzyme A. RHEA:25605|MetaCyc:RXNQT-4163 go-plus.json http://purl.obolibrary.org/obo/GO_0103079 GO:0103077 biolink:MolecularActivity quercetin 3-glucoside 7-O-rhamnosyltransferase activity Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP. RHEA:61188|MetaCyc:RXNQT-4161 go-plus.json http://purl.obolibrary.org/obo/GO_0103077 GO:0103081 biolink:MolecularActivity methylthiopropylmalate dehydrogenase activity Catalysis of the reaction: 3-(3'-methylthio)propylmalate <=> H+ + 2-oxo-6-methylthiohexanoate + carbon dioxide. MetaCyc:RXNQT-4165 go-plus.json http://purl.obolibrary.org/obo/GO_0103081 GO:0103082 biolink:MolecularActivity 2-(4'-methylthio)butylmalate synthase activity Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A. MetaCyc:RXNQT-4166 go-plus.json http://purl.obolibrary.org/obo/GO_0103082 GO:0103080 biolink:MolecularActivity methylthiopropylmalate isomerase activity Catalysis of the reaction: 2-(3-methylthiopropyl)malate(2-) <=> 3-(3'-methylthio)propylmalate. RHEA:50644|MetaCyc:RXNQT-4164 go-plus.json http://purl.obolibrary.org/obo/GO_0103080 GO:0103001 biolink:MolecularActivity dimethylsulfoxide oxygenase activity Catalysis of the reaction: dimethyl sulfoxide + O2 + NADPH + H+ <=> sulfonyldimethane + H2O + NADP. MetaCyc:RXN-9767|RHEA:57956 go-plus.json http://purl.obolibrary.org/obo/GO_0103001 GO:0103002 biolink:MolecularActivity 16-hydroxypalmitate dehydrogenase activity Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH. MetaCyc:RXN-9802 go-plus.json http://purl.obolibrary.org/obo/GO_0103002 GO:0103000 biolink:MolecularActivity UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+. MetaCyc:RXN-9748 go-plus.json http://purl.obolibrary.org/obo/GO_0103000 GO:0103005 biolink:MolecularActivity 9,10-epoxystearate hydrolase activity Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate. MetaCyc:RXN-9806 go-plus.json http://purl.obolibrary.org/obo/GO_0103005 GO:0103006 biolink:MolecularActivity 9,10-dihydroxystearate hydroxylase activity Catalysis of the reaction: H+ + (9R,10S)-dihydroxystearate + O2 + NADPH <=> 9,10,18-trihydroxystearate + H2O + NADP. MetaCyc:RXN-9807 go-plus.json http://purl.obolibrary.org/obo/GO_0103006 GO:0103003 biolink:MolecularActivity oleate peroxygenase activity Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol. MetaCyc:RXN-9804 go-plus.json http://purl.obolibrary.org/obo/GO_0103003 GO:0103004 biolink:MolecularActivity 9,10-epoxystearate hydroxylase activity Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP. MetaCyc:RXN-9805 go-plus.json http://purl.obolibrary.org/obo/GO_0103004 GO:0103009 biolink:MolecularActivity 3-chlorotoluene monooxygenase activity Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O. MetaCyc:RXN-9908 go-plus.json http://purl.obolibrary.org/obo/GO_0103009 GO:0103007 biolink:MolecularActivity indole-3-acetate carboxyl methyltransferase activity Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine <=> methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine. MetaCyc:RXN-9825|RHEA:36131|EC:2.1.1.278 go-plus.json http://purl.obolibrary.org/obo/GO_0103007 GO:0103008 biolink:MolecularActivity 4-chloro-2-methylphenoxyacetate oxygenase activity Catalysis of the reaction: 4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + 2-oxo monocarboxylic acid anion + succinate + carbon dioxide. MetaCyc:RXN-9864 go-plus.json http://purl.obolibrary.org/obo/GO_0103008 GO:0103012 biolink:MolecularActivity ferredoxin-thioredoxin reductase activity Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. MetaCyc:RXN-9944|RHEA:42336|EC:1.8.7.2 go-plus.json ferredoxin:thioredoxin reductase activity http://purl.obolibrary.org/obo/GO_0103012 GO:0103010 biolink:MolecularActivity gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming) Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide. MetaCyc:RXN-991 go-plus.json http://purl.obolibrary.org/obo/GO_0103010 GO:0103011 biolink:MolecularActivity mannosylfructose-phosphate synthase activity Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP. RHEA:26039|EC:2.4.1.246|MetaCyc:RXN-9935 go-plus.json http://purl.obolibrary.org/obo/GO_0103011 GO:0103016 biolink:MolecularActivity tRNA-specific 2-thiouridylase activity Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine. MetaCyc:RXN0-2023 go-plus.json http://purl.obolibrary.org/obo/GO_0103016 GO:0103014 biolink:MolecularActivity beta-keto ester reductase activity Catalysis of the reaction: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP = ethyl-2-methylacetoacetate + NADPH + H+. MetaCyc:RXN0-1941 go-plus.json http://purl.obolibrary.org/obo/GO_0103014 GO:0103015 biolink:MolecularActivity 4-amino-4-deoxy-L-arabinose transferase activity Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate. RHEA:35371|MetaCyc:RXN0-2001|EC:2.4.2.43 go-plus.json http://purl.obolibrary.org/obo/GO_0103015 GO:0103019 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103019 GO:0103020 biolink:MolecularActivity 1-deoxy-D-xylulose kinase activity Catalysis of the reaction: 1-deoxy-D-xylulose + ATP <=> H+ + 1-deoxy-D-xylulose 5-phosphate + ADP. RHEA:27990|MetaCyc:RXN0-382 go-plus.json http://purl.obolibrary.org/obo/GO_0103020 GO:0103023 biolink:MolecularActivity ITPase activity Catalysis of the reaction: ITP + H2O <=> H+ + IDP + hydrogenphosphate. MetaCyc:RXN0-5073|RHEA:28330 go-plus.json http://purl.obolibrary.org/obo/GO_0103023 GO:0103024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103024 GO:0103027 biolink:MolecularActivity FMN phosphatase activity Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate. MetaCyc:RXN0-5187 go-plus.json http://purl.obolibrary.org/obo/GO_0103027 GO:0103028 biolink:MolecularActivity murein hydrolase activity Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide. MetaCyc:RXN0-5190 go-plus.json http://purl.obolibrary.org/obo/GO_0103028 GO:0103025 biolink:MolecularActivity alpha-amylase activity (releasing maltohexaose) Catalysis of the reaction: n H2O + a 1,4-alpha-D-glucan = alpha-maltohexaose + a 1,4-alpha-D-glucan. MetaCyc:RXN0-5181|EC:3.2.1.1 go-plus.json http://purl.obolibrary.org/obo/GO_0103025 GO:0103026 biolink:MolecularActivity fructose-1-phosphatase activity Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate. RHEA:35603|MetaCyc:RXN0-5186 go-plus.json http://purl.obolibrary.org/obo/GO_0103026 CHEBI:140297 biolink:ChemicalSubstance 4'-O-demethylsordarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_140297 CHEBI:140294 biolink:ChemicalSubstance 5'-triphosphoadenylyl-(2'->5')-adenosine(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140294 chebi_ph7_3 OBO:go/extensions/ro_pending#results_in_transport_through biolink:OntologyClass obsolete results_in_transport_through go-plus.json http://purl.obolibrary.org/obo/go/extensions/ro_pending#results_in_transport_through CHEBI:139296 biolink:ChemicalSubstance D-alanyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_139296 GO:0103030 biolink:MolecularActivity ethylglyoxal reductase (NADH-dependent, hydroxyacetone-forming) activity Catalysis of the reaction: H+ + methylglyoxal + NADH = hydroxyacetone + NAD. MetaCyc:RXN0-5213|RHEA:35615 go-plus.json http://purl.obolibrary.org/obo/GO_0103030 GO:0103031 biolink:MolecularActivity L-Ala-D/L-Glu epimerase activity Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate. RHEA:28394|MetaCyc:RXN0-5228 go-plus.json http://purl.obolibrary.org/obo/GO_0103031 GO:0103035 biolink:MolecularActivity NAD(P)H:methyl-1,4-benzoquinone oxidoreductase activity Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP. MetaCyc:RXN0-5387 go-plus.json http://purl.obolibrary.org/obo/GO_0103035 GO:0103032 biolink:MolecularActivity tartronate semialdehyde reductase activity Catalysis of the reaction: D-glycerate + NAD <=> H+ + 2-hydroxy-3-oxopropanoate + NADH. MetaCyc:RXN0-5289|RHEA:18845 go-plus.json http://purl.obolibrary.org/obo/GO_0103032 GO:0103033 biolink:MolecularActivity beta-galactosidase activity (lactose isomerization) Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose. MetaCyc:RXN0-5363 go-plus.json http://purl.obolibrary.org/obo/GO_0103033 GO:0103039 biolink:MolecularActivity protein methylthiotransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor. RHEA:37087|MetaCyc:RXN0-6366|EC:2.8.4.4 go-plus.json http://purl.obolibrary.org/obo/GO_0103039 GO:0103036 biolink:MolecularActivity NADH:menaquinone oxidoreductase activity Catalysis of the reaction: 5 H+ + NADH + a menaquinone <=> 4 H+ + NAD + a menaquinol. MetaCyc:RXN0-5388 go-plus.json http://purl.obolibrary.org/obo/GO_0103036 GO:0103037 biolink:MolecularActivity L-glyceraldehyde 3-phosphate reductase activity Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH. MetaCyc:RXN0-5410 go-plus.json http://purl.obolibrary.org/obo/GO_0103037 CHEBI:140286 biolink:ChemicalSubstance deoxyribonucleoside 5'-methylphosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_140286 chebi_ph7_3 CHEBI:140284 biolink:ChemicalSubstance deoxyribonucleotide residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_140284 chebi_ph7_3 GO:0010929 biolink:BiologicalProcess positive regulation of auxin mediated signaling pathway Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. go-plus.json positive regulation of auxin mediated signalling pathway http://purl.obolibrary.org/obo/GO_0010929 GO:0044261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044261 GO:0044262 biolink:BiologicalProcess cellular carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. go-plus.json cellular carbohydrate metabolism|main pathways of carbohydrate metabolic process|main pathways of carbohydrate metabolism http://purl.obolibrary.org/obo/GO_0044262 GO:0010927 biolink:BiologicalProcess cellular component assembly involved in morphogenesis The cellular component assembly that is part of the initial shaping of the component during its developmental progression. go-plus.json http://purl.obolibrary.org/obo/GO_0010927 GO:0044260 biolink:BiologicalProcess cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. go-plus.json cellular biopolymer metabolic process|cellular macromolecule metabolism http://purl.obolibrary.org/obo/GO_0044260 GO:0010928 biolink:BiologicalProcess regulation of auxin mediated signaling pathway Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. go-plus.json regulation of auxin mediated signalling pathway http://purl.obolibrary.org/obo/GO_0010928 CHEBI:23557 biolink:ChemicalSubstance dTDP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_23557 GO:0044269 biolink:BiologicalProcess glycerol ether catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. go-plus.json glycerol ether degradation|glycerol ether breakdown|glycerol ether catabolism http://purl.obolibrary.org/obo/GO_0044269 GO:0010921 biolink:BiologicalProcess regulation of phosphatase activity Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010921 GO:0010922 biolink:BiologicalProcess positive regulation of phosphatase activity Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010922 GO:0044267 biolink:BiologicalProcess cellular protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. go-plus.json cellular protein metabolism http://purl.obolibrary.org/obo/GO_0044267 GO:0044268 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044268 GO:0010920 biolink:BiologicalProcess negative regulation of inositol phosphate biosynthetic process Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. go-plus.json negative regulation of inositol phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0010920 GO:0044265 biolink:BiologicalProcess cellular macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. go-plus.json cellular macromolecule degradation|cellular macromolecule breakdown|cellular biopolymer catabolic process|cellular macromolecule catabolism http://purl.obolibrary.org/obo/GO_0044265 GO:0010925 biolink:BiologicalProcess positive regulation of inositol-polyphosphate 5-phosphatase activity Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010925 GO:0010926 biolink:BiologicalProcess obsolete anatomical structure formation OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. go-plus.json anatomical structure formation http://purl.obolibrary.org/obo/GO_0010926 GO:0044266 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044266 GO:0010923 biolink:BiologicalProcess negative regulation of phosphatase activity Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010923 GO:0044263 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044263 GO:0044264 biolink:BiologicalProcess cellular polysaccharide metabolic process The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells. go-plus.json cellular glycan metabolism|cellular glycan metabolic process|cellular polysaccharide metabolism http://purl.obolibrary.org/obo/GO_0044264 GO:0010924 biolink:BiologicalProcess regulation of inositol-polyphosphate 5-phosphatase activity Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0010924 UBERON:0004781 biolink:AnatomicalEntity gall bladder lamina propria A lamina propria that is part of a gallbladder [Automatically generated definition]. go-plus.json lamina propria of gallbladder|gall bladder lamina propria mucosa|lamina propria of gall bladder|lamina propria mucosa of gallbladder|biliary lamina propria|gallbladder lamina propria|gallbladder lamina propria mucosa|lamina propria mucosa of gall bladder http://purl.obolibrary.org/obo/UBERON_0004781 UBERON:0004782 biolink:AnatomicalEntity gastrointestinal system serosa A serous membrane that is part of a digestive system [Automatically generated definition]. go-plus.json gastrointestinal system serous membrane|serosa of gastrointestinal system|serous membrane of digestive system|digestive system serosa|serosa of digestive system|digestive system serous membrane|serous membrane of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0004782 UBERON:0004780 biolink:AnatomicalEntity gastrointestinal system lamina propria A lamina propria that is part of a gastrointestinal system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004780 GO:0009930 biolink:CellularComponent longitudinal side of cell surface The side of the cell parallel to the zygotic axis. go-plus.json http://purl.obolibrary.org/obo/GO_0009930 GO:0009931 biolink:MolecularActivity calcium-dependent protein serine/threonine kinase activity Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0009931 UBERON:0004789 biolink:AnatomicalEntity larynx mucous gland A mucous gland that is part of a larynx [Automatically generated definition]. go-plus.json mucous gland of larynx http://purl.obolibrary.org/obo/UBERON_0004789 GO:0009932 biolink:BiologicalProcess cell tip growth Growth that occurs specifically at the tip of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0009932 GO:0009933 biolink:BiologicalProcess meristem structural organization Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue. go-plus.json meristem organisation|meristem organization http://purl.obolibrary.org/obo/GO_0009933 GO:0009934 biolink:BiologicalProcess regulation of meristem structural organization Any process that modulates the frequency, rate or extent of meristem organization. go-plus.json regulation of meristem organisation|regulation of meristem organization http://purl.obolibrary.org/obo/GO_0009934 UBERON:0004787 biolink:AnatomicalEntity urethra urothelium An urothelium that is part of a urethra [Automatically generated definition]. go-plus.json urothelium of urethra|uroepithelium of urethra|urethra uroepithelium http://purl.obolibrary.org/obo/UBERON_0004787 UBERON:0004788 biolink:AnatomicalEntity kidney pelvis urothelium the epithelial lining of the luminal space of the kidney pelvis go-plus.json transitional epithelium of kidney pelvis|pelvic urothelium|kidney pelvis transitional epithelium|transitional epithelium of renal pelvis|renal pelvis urothelium|urothelium of kidney pelvis|uroepithelium of pelvis of ureter|renal pelvis transitional epithelium|uroepithelium of kidney pelvis|pelvis of ureter urothelium|urothelium of pelvis of ureter|kidney pelvis uroepithelium|uroepithelium of renal pelvis|pelvis of ureter uroepithelium|urothelium of renal pelvis|renal pelvis uroepithelium http://purl.obolibrary.org/obo/UBERON_0004788 GO:0009935 biolink:BiologicalProcess obsolete nutrient import OBSOLETE. The directed movement of nutrients into a cell or organelle. go-plus.json nutrient import|nutrient uptake http://purl.obolibrary.org/obo/GO_0009935 UBERON:0004785 biolink:AnatomicalEntity respiratory system mucosa the mucous membrane lining the respiratory tract go-plus.json laryngeal mucous membrane|mucosa of organ of respiratory system|respiratory mucosa|mucous membrane of apparatus respiratorius|mucosa of respiratory system|mucosa of apparatus respiratorius|mucous membrane of respiratory system|mucosa of organ of apparatus respiratorius|respiratory system mucosa of organ|apparatus respiratorius mucosa|respiratory system mucous membrane|apparatus respiratorius mucosa of organ|respiratory tract mucosa|apparatus respiratorius mucous membrane http://purl.obolibrary.org/obo/UBERON_0004785 GO:0009936 biolink:MolecularActivity obsolete expansin OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa. go-plus.json expansin http://purl.obolibrary.org/obo/GO_0009936 UBERON:0004786 biolink:AnatomicalEntity gastrointestinal system mucosa A mucosa that is part of a gastrointestinal system. go-plus.json mucosa of gut|gut mucuous membrane|digestive tract mucosa|gut mucosa http://purl.obolibrary.org/obo/UBERON_0004786 GO:0009937 biolink:BiologicalProcess regulation of gibberellic acid mediated signaling pathway Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling. go-plus.json regulation of gibberellic acid mediated signalling http://purl.obolibrary.org/obo/GO_0009937 GO:0009938 biolink:BiologicalProcess negative regulation of gibberellic acid mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity. go-plus.json downregulation of gibberellic acid mediated signaling|down-regulation of gibberellic acid mediated signaling|negative regulation of gibberellic acid mediated signalling|inhibition of gibberellic acid mediated signaling|down regulation of gibberellic acid mediated signaling http://purl.obolibrary.org/obo/GO_0009938 UBERON:0004783 biolink:AnatomicalEntity gall bladder serosa A serous membrane that is part of a gallbladder [Automatically generated definition]. go-plus.json tunica serosa (vesica biliaris)|biliary serosa|gallbladder serosa|gallbladder serous membrane|serous coat of gallbladder|serous membrane of gall bladder|gall bladder serous membrane|serosa of gall bladder|serosa of gallbladder|serous membrane of gallbladder|tunica serosa vesicae biliaris http://purl.obolibrary.org/obo/UBERON_0004783 NCBITaxon:164328 biolink:OrganismalEntity Phytophthora ramorum go-plus.json ramorum blight|sudden oak death|Sudden oak death agent http://purl.obolibrary.org/obo/NCBITaxon_164328 UBERON:0004784 biolink:AnatomicalEntity heart ventricle wall An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]. go-plus.json wall of cardiac ventricle|wall of ventricle|ventricle of heart anatomical wall|cardiac ventricle anatomical wall|wall of lower chamber of heart|anatomical wall of lower chamber of heart|lower chamber of heart wall|ventricular wall|anatomical wall of heart ventricle|lower chamber of heart anatomical wall|wall of heart ventricle|wall of ventricle of heart|cardiac ventricle wall|heart ventricle anatomical wall|anatomical wall of ventricle of heart|ventricle of heart wall|anatomical wall of cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0004784 GO:0009939 biolink:BiologicalProcess positive regulation of gibberellic acid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity. go-plus.json up regulation of gibberellic acid mediated signaling|activation of gibberellic acid mediated signaling|stimulation of gibberellic acid mediated signaling|up-regulation of gibberellic acid mediated signaling|positive regulation of gibberellic acid mediated signalling|upregulation of gibberellic acid mediated signaling http://purl.obolibrary.org/obo/GO_0009939 GO:0044272 biolink:BiologicalProcess sulfur compound biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. go-plus.json sulfur compound anabolism|sulfur compound synthesis|sulfur compound formation|sulfur compound biosynthesis|sulfur biosynthesis|sulfur biosynthetic process http://purl.obolibrary.org/obo/GO_0044272 GO:0044273 biolink:BiologicalProcess sulfur compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. go-plus.json sulfur compound catabolism|sulfur catabolic process|sulfur catabolism|sulfur compound degradation|sulfur compound breakdown http://purl.obolibrary.org/obo/GO_0044273 GO:0044270 biolink:BiologicalProcess cellular nitrogen compound catabolic process The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. go-plus.json nitrogen compound degradation|nitrogen compound breakdown|nitrogen compound catabolism http://purl.obolibrary.org/obo/GO_0044270 GO:0010938 biolink:BiologicalProcess cytoplasmic microtubule depolymerization The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0010938 GO:0044271 biolink:BiologicalProcess cellular nitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. go-plus.json nitrogen compound biosynthesis|nitrogen compound anabolism|nitrogen compound synthesis|nitrogen compound formation http://purl.obolibrary.org/obo/GO_0044271 GO:0010939 biolink:BiologicalProcess regulation of necrotic cell death Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. go-plus.json http://purl.obolibrary.org/obo/GO_0010939 UBERON:0004769 biolink:AnatomicalEntity diaphysis Subdivision of long bone which forms the part of the bone between the two epiphyses, excluding the metaphyses[FMA,modified]. go-plus.json long bone diaphysis|body of long bone|shaft of long bone http://purl.obolibrary.org/obo/UBERON_0004769 GO:0010932 biolink:BiologicalProcess regulation of macrophage tolerance induction Any process that modulates the frequency, rate, or extent of macrophage tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0010932 GO:0010933 biolink:BiologicalProcess positive regulation of macrophage tolerance induction Any process that increases the frequency, rate, or extent of B cell tolerance induction. go-plus.json http://purl.obolibrary.org/obo/GO_0010933 GO:0044278 biolink:BiologicalProcess cell wall disruption in other organism A process carried out by an organism that results in the breakdown of the cell wall of a second organism. go-plus.json http://purl.obolibrary.org/obo/GO_0044278 GO:0010930 biolink:BiologicalProcess negative regulation of auxin mediated signaling pathway Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. go-plus.json negative regulation of auxin mediated signalling pathway http://purl.obolibrary.org/obo/GO_0010930 GO:0010931 biolink:BiologicalProcess macrophage tolerance induction A process involving any mechanism for tolerance induction in macrophages. go-plus.json http://purl.obolibrary.org/obo/GO_0010931 GO:0044279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044279 GO:0010936 biolink:BiologicalProcess negative regulation of macrophage cytokine production Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0010936 GO:0044276 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044276 GO:0044277 biolink:BiologicalProcess cell wall disassembly A process that results in the breakdown of the cell wall. go-plus.json cellular cell wall disassembly http://purl.obolibrary.org/obo/GO_0044277 GO:0010937 biolink:BiologicalProcess regulation of cytoplasmic microtubule depolymerization Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization. go-plus.json http://purl.obolibrary.org/obo/GO_0010937 GO:0044274 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044274 GO:0010934 biolink:BiologicalProcess macrophage cytokine production The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0010934 gocheck_do_not_annotate GO:0044275 biolink:BiologicalProcess cellular carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. go-plus.json cellular carbohydrate degradation|cellular carbohydrate breakdown|cellular carbohydrate catabolism http://purl.obolibrary.org/obo/GO_0044275 GO:0010935 biolink:BiologicalProcess regulation of macrophage cytokine production Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0010935 UBERON:0004770 biolink:AnatomicalEntity articular system Anatomical system that consists of all the joints of the body. go-plus.json joint system|set of all joints of body|set of joints of body|set of all joints http://purl.obolibrary.org/obo/UBERON_0004770 UBERON:0004771 biolink:AnatomicalEntity posterior nasal aperture Opening/conduit between the nasal cavity and the nasopharynx[AAO] The choanae are separated by the vomer[WP]. go-plus.json posterior choana|posterior naris|choana|internal naris|nasopharyngeal naris|choanae|posterior nasal apperture http://purl.obolibrary.org/obo/UBERON_0004771 CHEBI:1135 biolink:ChemicalSubstance 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1135 GO:0009940 biolink:MolecularActivity amino-terminal vacuolar sorting propeptide binding Binding to an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0009940 GO:0009941 biolink:CellularComponent chloroplast envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0009941 GO:0009942 biolink:BiologicalProcess longitudinal axis specification The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root. go-plus.json longitudinal axis determination|apical-basal pattern specification http://purl.obolibrary.org/obo/GO_0009942 GO:0009943 biolink:BiologicalProcess adaxial/abaxial axis specification The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure. go-plus.json adaxial/abaxial determination http://purl.obolibrary.org/obo/GO_0009943 UBERON:0004778 biolink:AnatomicalEntity larynx submucosa A submucosa that is part of a larynx [Automatically generated definition]. go-plus.json laryngeal submucosa|submucosa of larynx http://purl.obolibrary.org/obo/UBERON_0004778 GO:0009944 biolink:BiologicalProcess polarity specification of adaxial/abaxial axis The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/GO_0009944 UBERON:0004779 biolink:AnatomicalEntity respiratory system lamina propria A lamina propria that is part of a respiratory system [Automatically generated definition]. go-plus.json lamina propria of apparatus respiratorius|lamina propria mucosa of respiratory system|respiratory system lamina propria mucosa|lamina propria mucosa of apparatus respiratorius|lamina propria of respiratory system|apparatus respiratorius lamina propria mucosa|apparatus respiratorius lamina propria http://purl.obolibrary.org/obo/UBERON_0004779 GO:0009945 biolink:BiologicalProcess radial axis specification The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point. go-plus.json http://purl.obolibrary.org/obo/GO_0009945 GO:0009946 biolink:BiologicalProcess proximal/distal axis specification The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end). go-plus.json proximodistal axis specification|proximal/distal axis determination http://purl.obolibrary.org/obo/GO_0009946 UBERON:0004777 biolink:AnatomicalEntity respiratory system submucosa A submucosa that is part of a respiratory system [Automatically generated definition]. go-plus.json apparatus respiratorius submucosa|submucosa of apparatus respiratorius|submucosa of respiratory system http://purl.obolibrary.org/obo/UBERON_0004777 GO:0009947 biolink:BiologicalProcess centrolateral axis specification The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf. go-plus.json centrolateral axis determination|mediolateral axis specification http://purl.obolibrary.org/obo/GO_0009947 GO:0009948 biolink:BiologicalProcess anterior/posterior axis specification The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. go-plus.json anterior/posterior axis determination http://purl.obolibrary.org/obo/GO_0009948 GO:0009949 biolink:BiologicalProcess polarity specification of anterior/posterior axis Any process resulting in the establishment of polarity along the anterior/posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0009949 UBERON:0004772 biolink:AnatomicalEntity eyelid tarsus The tarsi (tarsal plates) are two comparatively thick, elongated plates of dense connective tissue, about 2.5 cm. in length; one is found in each eyelid, and contributes to its form and support. They directly abut the lid margins. go-plus.json tarsus palpebralis|tarsi|tarsal plate|tarsal plate of eyelid|eyelid tarsi http://purl.obolibrary.org/obo/UBERON_0004772 GO:0009918 biolink:MolecularActivity sterol delta7 reductase activity Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol. MetaCyc:RXN-707 go-plus.json sterol delta-7 reductase activity http://purl.obolibrary.org/obo/GO_0009918 GO:0010907 biolink:BiologicalProcess positive regulation of glucose metabolic process Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. go-plus.json positive regulation of glucose metabolism http://purl.obolibrary.org/obo/GO_0010907 GO:0044283 biolink:BiologicalProcess small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. go-plus.json small molecule biosynthesis http://purl.obolibrary.org/obo/GO_0044283 GO:0009919 biolink:BiologicalProcess obsolete cytokinesis (sensu Viridiplantae) OBSOLETE. The division of a cell into two daughter cells with cell walls. go-plus.json cytokinesis (sensu Viridiplantae) http://purl.obolibrary.org/obo/GO_0009919 GO:0044284 biolink:CellularComponent mitochondrial crista junction A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane. go-plus.json cristae junction|crista junction http://purl.obolibrary.org/obo/GO_0044284 GO:0010908 biolink:BiologicalProcess regulation of heparan sulfate proteoglycan biosynthetic process Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues. go-plus.json http://purl.obolibrary.org/obo/GO_0010908 GO:0044281 biolink:BiologicalProcess small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. go-plus.json small molecule metabolism http://purl.obolibrary.org/obo/GO_0044281 goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_metagenomics GO:0010905 biolink:BiologicalProcess negative regulation of UDP-glucose catabolic process Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. go-plus.json negative regulation of UDP-glucose catabolism http://purl.obolibrary.org/obo/GO_0010905 GO:0044282 biolink:BiologicalProcess small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. go-plus.json small molecule catabolism http://purl.obolibrary.org/obo/GO_0044282 GO:0010906 biolink:BiologicalProcess regulation of glucose metabolic process Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. go-plus.json regulation of glucose metabolism http://purl.obolibrary.org/obo/GO_0010906 CHEBI:23530 biolink:ChemicalSubstance cytokinin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23530 GO:0044280 biolink:CellularComponent subplasmalemmal coating Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier. NIF_Subcellular:sao1938587839 go-plus.json http://purl.obolibrary.org/obo/GO_0044280 UBERON:0004758 biolink:AnatomicalEntity salt gland An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004758 GO:0010909 biolink:BiologicalProcess positive regulation of heparan sulfate proteoglycan biosynthetic process Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues. go-plus.json http://purl.obolibrary.org/obo/GO_0010909 UBERON:0004759 biolink:AnatomicalEntity cranial salt gland A salt gland located in the cranium or head region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004759 GO:0010900 biolink:BiologicalProcess negative regulation of phosphatidylcholine catabolic process Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. go-plus.json http://purl.obolibrary.org/obo/GO_0010900 CHEBI:1109 biolink:ChemicalSubstance 2-hexaprenyl-6-methoxyphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1109 chebi_ph7_3 GO:0044289 biolink:CellularComponent mitochondrial inner-outer membrane contact site Sites of close apposition of the inner and outer mitochondrial membrane. go-plus.json contact site|bridge contact site http://purl.obolibrary.org/obo/GO_0044289 GO:0010903 biolink:BiologicalProcess negative regulation of very-low-density lipoprotein particle remodeling Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json negative regulation of VLDL remodeling http://purl.obolibrary.org/obo/GO_0010903 GO:0044287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044287 GO:0044288 biolink:CellularComponent puncta adhaerentia A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells. NIF_Subcellular:sao257629430 go-plus.json http://purl.obolibrary.org/obo/GO_0044288 GO:0010904 biolink:BiologicalProcess regulation of UDP-glucose catabolic process Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. go-plus.json regulation of UDP-glucose catabolism http://purl.obolibrary.org/obo/GO_0010904 GO:0010901 biolink:BiologicalProcess regulation of very-low-density lipoprotein particle remodeling Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json regulation of VLDL remodeling http://purl.obolibrary.org/obo/GO_0010901 GO:0044285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0044285 GO:0010902 biolink:BiologicalProcess positive regulation of very-low-density lipoprotein particle remodeling Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. go-plus.json positive regulation of VLDL remodeling http://purl.obolibrary.org/obo/GO_0010902 GO:0044286 biolink:CellularComponent peg and socket contact A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells. NIF_Subcellular:sao1943947957 go-plus.json ball and socket contact http://purl.obolibrary.org/obo/GO_0044286 UBERON:0004760 biolink:AnatomicalEntity gland of anal canal A gland that is part of an anal canal [Automatically generated definition]. go-plus.json rectal gland|gland of anal canal|anal sac|anal gland|gland of anus http://purl.obolibrary.org/obo/UBERON_0004760 CHEBI:1107 biolink:ChemicalSubstance 2-hexaprenyl-6-hydroxyphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1107 chebi_ph7_3 GO:0009910 biolink:BiologicalProcess negative regulation of flower development Any process that stops, prevents, or reduces the frequency, rate or extent of flower development. go-plus.json down regulation of flower development|inhibition of flower development|down-regulation of flower development|downregulation of flower development http://purl.obolibrary.org/obo/GO_0009910 UBERON:0004767 biolink:AnatomicalEntity vomerine tooth A tooth that is on the vomer. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004767 GO:0009911 biolink:BiologicalProcess positive regulation of flower development Any process that activates or increases the frequency, rate or extent of flower development. go-plus.json upregulation of flower development|stimulation of flower development|up-regulation of flower development|activation of flower development|up regulation of flower development http://purl.obolibrary.org/obo/GO_0009911 UBERON:0004768 biolink:AnatomicalEntity bone of lower jaw Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular go-plus.json lower jaw bone http://purl.obolibrary.org/obo/UBERON_0004768 GO:0009912 biolink:BiologicalProcess auditory receptor cell fate commitment The process in which the cellular identity of auditory hair cells is acquired and determined. go-plus.json auditory hair cell fate commitment http://purl.obolibrary.org/obo/GO_0009912 UBERON:0004765 biolink:AnatomicalEntity skeletal element Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004765 UBERON:0004766 biolink:AnatomicalEntity cranial bone A bone that is part of a cranium. go-plus.json cranium bone http://purl.obolibrary.org/obo/UBERON_0004766 GO:0009913 biolink:BiologicalProcess epidermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. go-plus.json hypodermal cell differentiation http://purl.obolibrary.org/obo/GO_0009913 GO:0009914 biolink:BiologicalProcess hormone transport The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0009914 goslim_pir UBERON:0004763 biolink:AnatomicalEntity endochondral bone tissue Replacement bone tissue that forms within cartilage[VSAO, modified]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004763 UBERON:0004764 biolink:AnatomicalEntity intramembranous bone tissue Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004764 GO:0009915 biolink:BiologicalProcess phloem sucrose loading The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink. go-plus.json http://purl.obolibrary.org/obo/GO_0009915 UBERON:0004761 biolink:AnatomicalEntity cartilaginous neurocranium The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. go-plus.json cartilaginous skull|cartilaginous chondocranium|chondocranium|cartiligionous skeletal structure of skull|embryonic chondocranium|neurocranium http://purl.obolibrary.org/obo/UBERON_0004761 GO:0009916 biolink:MolecularActivity alternative oxidase activity Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product. go-plus.json http://purl.obolibrary.org/obo/GO_0009916 GO:0009917 biolink:MolecularActivity sterol 5-alpha reductase activity Catalysis of the removal of a C-5 double bond in the B ring of a sterol. go-plus.json http://purl.obolibrary.org/obo/GO_0009917 GO:0010918 biolink:BiologicalProcess positive regulation of mitochondrial membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json elevation of mitochondrial membrane potential http://purl.obolibrary.org/obo/GO_0010918 GO:0044294 biolink:CellularComponent dendritic growth cone The migrating motile tip of a growing nerve cell dendrite. NIF_Subcellular:sao1594955670 go-plus.json dendrite growth cone http://purl.obolibrary.org/obo/GO_0044294 GO:0009929 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009929 GO:0010919 biolink:BiologicalProcess regulation of inositol phosphate biosynthetic process Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. go-plus.json regulation of inositol phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0010919 GO:0044295 biolink:CellularComponent axonal growth cone The migrating motile tip of a growing nerve cell axon. NIF_Subcellular:sao203987954|NIF_Subcellular:sao1594955670 go-plus.json axon growth cone http://purl.obolibrary.org/obo/GO_0044295 GO:0010916 biolink:BiologicalProcess negative regulation of very-low-density lipoprotein particle clearance Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json negative regulation of VLDL particle clearance|negative regulation of VLDL clearance http://purl.obolibrary.org/obo/GO_0010916 GO:0044292 biolink:CellularComponent dendrite terminus A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole. NIF_Subcellular:sao28175134 go-plus.json dendrite terminal specialization|dendrite terminal|terminal specialization of a dendrite|terminal specialization http://purl.obolibrary.org/obo/GO_0044292 GO:0010917 biolink:BiologicalProcess negative regulation of mitochondrial membrane potential Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json reduction of mitochondrial membrane potential http://purl.obolibrary.org/obo/GO_0010917 GO:0044293 biolink:CellularComponent dendriole Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC). NIF_Subcellular:sao28175134|NIF_Subcellular:sao295057932 go-plus.json http://purl.obolibrary.org/obo/GO_0044293 GO:0044290 biolink:CellularComponent mitochondrial intracristal space The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space. NIF_Subcellular:sao508958414 go-plus.json http://purl.obolibrary.org/obo/GO_0044290 UBERON:0004749 biolink:AnatomicalEntity blastodisc A small, circular, white spot (approximately 2-3 mm across) on the surface of the yellow yolk of an egg that has been laid. The nucleus of the egg is in the germinal disc. go-plus.json germ disc|embryonic disc|gastrodisk|germinal disc http://purl.obolibrary.org/obo/UBERON_0004749 GO:0044291 biolink:CellularComponent cell-cell contact zone Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle. NIF_Subcellular:sao1299635018 go-plus.json cell cell contact zone http://purl.obolibrary.org/obo/GO_0044291 GO:0010910 biolink:BiologicalProcess positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_0010910 GO:0010911 biolink:BiologicalProcess regulation of isomerase activity Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. go-plus.json http://purl.obolibrary.org/obo/GO_0010911 GO:0010914 biolink:BiologicalProcess positive regulation of sterigmatocystin biosynthetic process Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. go-plus.json http://purl.obolibrary.org/obo/GO_0010914 GO:0044298 biolink:CellularComponent cell body membrane The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections. go-plus.json cell soma membrane http://purl.obolibrary.org/obo/GO_0044298 GO:0044299 biolink:CellularComponent C-fiber The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated. NIF_Subcellular:nlx_subcell_20090210 go-plus.json C-fibre http://purl.obolibrary.org/obo/GO_0044299 GO:0010915 biolink:BiologicalProcess regulation of very-low-density lipoprotein particle clearance Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json regulation of VLDL particle clearance|regulation of VLDL clearance http://purl.obolibrary.org/obo/GO_0010915 GO:0010912 biolink:BiologicalProcess positive regulation of isomerase activity Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. go-plus.json http://purl.obolibrary.org/obo/GO_0010912 GO:0044296 biolink:CellularComponent dendritic tuft The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance. NIF_Subcellular:sao1340260079 go-plus.json dendrite tuft http://purl.obolibrary.org/obo/GO_0044296 GO:0044297 biolink:CellularComponent cell body The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. Wikipedia:Cell_body|FMA:67301|FBbt:00005107 go-plus.json cell soma http://purl.obolibrary.org/obo/GO_0044297 GO:0010913 biolink:BiologicalProcess regulation of sterigmatocystin biosynthetic process Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. go-plus.json http://purl.obolibrary.org/obo/GO_0010913 CHEBI:1113 biolink:ChemicalSubstance cis-2-hydroxypenta-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1113 OBO:GOCHE_75763 biolink:OntologyClass substance with eukaryotic metabolite role go-plus.json http://purl.obolibrary.org/obo/GOCHE_75763 3_STAR GO:0009920 biolink:BiologicalProcess cell plate formation involved in plant-type cell wall biogenesis The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana. go-plus.json cell plate formation involved in cellulose and pectin-containing cell wall biogenesis http://purl.obolibrary.org/obo/GO_0009920 UBERON:0004756 biolink:AnatomicalEntity dermal skeletal element dermis-derived entity that is made of skeletal tissue. go-plus.json dermal element http://purl.obolibrary.org/obo/UBERON_0004756 GO:0009921 biolink:CellularComponent auxin efflux carrier complex The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0009921 GO:0009922 biolink:MolecularActivity fatty acid elongase activity Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C). MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|Reactome:R-HSA-548830|Reactome:R-HSA-2046095|Reactome:R-HSA-2046088|Reactome:R-HSA-2046083|Reactome:R-HSA-2046090|Reactome:R-HSA-548814|Reactome:R-HSA-548800|Reactome:R-HSA-2046100|Reactome:R-HSA-548815|Reactome:R-HSA-2046094 go-plus.json http://purl.obolibrary.org/obo/GO_0009922 UBERON:0004757 biolink:AnatomicalEntity rectal salt gland An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride. go-plus.json digitiform gland|rectal gland|glandula rectalis http://purl.obolibrary.org/obo/UBERON_0004757 GO:0009923 biolink:CellularComponent fatty acid elongase complex A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids. go-plus.json http://purl.obolibrary.org/obo/GO_0009923 GO:0009924 biolink:MolecularActivity octadecanal decarbonylase activity Catalysis of the reaction: octadecanal = heptadecane + CO. RHEA:30415|MetaCyc:OCTADECANAL-DECARBONYLASE-RXN|EC:4.1.99.5 go-plus.json octadecanal alkane-lyase activity http://purl.obolibrary.org/obo/GO_0009924 UBERON:0004755 biolink:AnatomicalEntity skeletal tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] go-plus.json http://purl.obolibrary.org/obo/UBERON_0004755 GO:0009925 biolink:CellularComponent basal plasma membrane The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. go-plus.json http://purl.obolibrary.org/obo/GO_0009925 UBERON:0004753 biolink:AnatomicalEntity scapulocoracoid Skeletal element that consists of the scapula and the coracoid[VSAO, modified]. go-plus.json coraco-scapular cartilage|scapulocoracoideum|scapulocoracoid cartilage|scapulo-coracoid cartilage http://purl.obolibrary.org/obo/UBERON_0004753 GO:0009926 biolink:BiologicalProcess auxin polar transport The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally. go-plus.json http://purl.obolibrary.org/obo/GO_0009926 UBERON:0004750 biolink:AnatomicalEntity blastoderm A layer of cells formed at one pole of macrolecithal eggs such as the yolky egg of birds. The yolk prevents the division from taking place through the egg, resulting in meroblastic cleavage during the many cleavage divisions. At the animal pole (containing less yolk than the vegetal pole), the zygote divides and subdivides, forming the blastoderm, which gradually spreads around the yolk and forms the embryo. The blastoderm is composed of two layers, the epiblast and the hypoblast, which enclose the fluid-filled blastocoel cavity. go-plus.json membrana germinativa|germinal membrane http://purl.obolibrary.org/obo/UBERON_0004750 GO:0009927 biolink:MolecularActivity histidine phosphotransfer kinase activity Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator. go-plus.json http://purl.obolibrary.org/obo/GO_0009927 CHEBI:1110 biolink:ChemicalSubstance 2-hexaprenylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_1110 chebi_ph7_3 GO:0009928 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009928 GO:0103085 biolink:MolecularActivity 2-(5'-methylthio)pentylmalate synthase activity Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A. MetaCyc:RXNQT-4169 go-plus.json http://purl.obolibrary.org/obo/GO_0103085 GO:0103086 biolink:MolecularActivity methylthiopentylmalate isomerase activity Catalysis of the reaction: 2-(5'-methylthio)pentylmalate <=> 3-(5'-methylthio)pentylmalate. MetaCyc:RXNQT-4170 go-plus.json http://purl.obolibrary.org/obo/GO_0103086 GO:0103083 biolink:MolecularActivity methylthiobutylmalate isomerase activity Catalysis of the reaction: 2-(4'-methylthio)butylmalate <=> 3-(4'-methylthio)butylmalate. MetaCyc:RXNQT-4167 go-plus.json http://purl.obolibrary.org/obo/GO_0103083 GO:0103084 biolink:MolecularActivity methylthiobutylmalate dehydrogenase activity Catalysis of the reaction: 3-(4'-methylthio)butylmalate <=> H+ + 2-oxo-7-methylthioheptanoate + carbon dioxide. MetaCyc:RXNQT-4168 go-plus.json http://purl.obolibrary.org/obo/GO_0103084 GO:0103089 biolink:MolecularActivity methylthiohexylmalate isomerase activity Catalysis of the reaction: 2-(6'-methylthio)hexylmalate <=> 3-(6'-methylthio)hexylmalate. MetaCyc:RXNQT-4173 go-plus.json http://purl.obolibrary.org/obo/GO_0103089 CHEBI:23511 biolink:ChemicalSubstance cysteinyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_23511 GO:0103087 biolink:MolecularActivity methylthiopentylmalate dehydrogenase activity Catalysis of the reaction: 3-(5'-methylthio)pentylmalate <=> H+ + 2-oxo-8-methylthiooctanoate + carbon dioxide. MetaCyc:RXNQT-4171 go-plus.json http://purl.obolibrary.org/obo/GO_0103087 GO:0103088 biolink:MolecularActivity 2-(6'-methylthio)hexylmalate synthase activity Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A. MetaCyc:RXNQT-4172 go-plus.json http://purl.obolibrary.org/obo/GO_0103088 CHEBI:23518 biolink:ChemicalSubstance cytidine 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23518 GO:0103092 biolink:MolecularActivity methylthioalkylmalate isomerase activity Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate. MetaCyc:RXNQT-4176 go-plus.json http://purl.obolibrary.org/obo/GO_0103092 GO:0103093 biolink:MolecularActivity methylthioalkylmalate dehydrogenase activity Catalysis of the reaction: 3-(7'-methylthio)heptylmalate <=> H+ + 2-oxo-10-methylthiodecanoate + carbon dioxide. MetaCyc:RXNQT-4178 go-plus.json http://purl.obolibrary.org/obo/GO_0103093 GO:0103090 biolink:MolecularActivity methylthiohexylmalate dehydrogenase activity Catalysis of the reaction: 3-(6'-methylthio)hexylmalate <=> H+ + 2-oxo-9-methylthiononanoate + carbon dioxide. MetaCyc:RXNQT-4174 go-plus.json http://purl.obolibrary.org/obo/GO_0103090 GO:0103091 biolink:MolecularActivity 2-(7'-methylthio)heptylmalate synthase activity Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A. MetaCyc:RXNQT-4175 go-plus.json http://purl.obolibrary.org/obo/GO_0103091 GO:0103096 biolink:MolecularActivity CYP79F1 dihomomethionine monooxygenase activity Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP. MetaCyc:RXNQT-4309|RHEA:32719 go-plus.json http://purl.obolibrary.org/obo/GO_0103096 GO:0009907 biolink:BiologicalProcess response to photoperiod, red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. go-plus.json http://purl.obolibrary.org/obo/GO_0009907 GO:0103097 biolink:MolecularActivity CYP79F1 trihomomethionine monooxygenase activity Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP + 6-methylthiohexanaldoxime. MetaCyc:RXNQT-4310|RHEA:32723 go-plus.json http://purl.obolibrary.org/obo/GO_0103097 GO:0009908 biolink:BiologicalProcess flower development The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0009908 goslim_plant CHEBI:23521 biolink:ChemicalSubstance cytidine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23521 GO:0009909 biolink:BiologicalProcess regulation of flower development Any process that modulates the frequency, rate or extent of flower development. go-plus.json http://purl.obolibrary.org/obo/GO_0009909 GO:0103095 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0103095 CHEBI:23524 biolink:ChemicalSubstance cytidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_23524 GO:0103098 biolink:MolecularActivity CYP79F1 tetrahomomethionine monooxygenase activity Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime. MetaCyc:RXNQT-4311 go-plus.json http://purl.obolibrary.org/obo/GO_0103098 GO:0103099 biolink:MolecularActivity UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP. EC:2.4.1.195|MetaCyc:RXNQT-4324 go-plus.json http://purl.obolibrary.org/obo/GO_0103099 CHEBI:23523 biolink:ChemicalSubstance cytidine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_23523 CHEBI:1178 biolink:ChemicalSubstance (2S)-2-isopropylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_1178 chebi_ph7_3 CHEBI:23528 biolink:ChemicalSubstance cytochalasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_23528 GO:0009900 biolink:BiologicalProcess dehiscence The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it. Wikipedia:Dehiscence_(botany) go-plus.json http://purl.obolibrary.org/obo/GO_0009900 GO:0009901 biolink:BiologicalProcess anther dehiscence The dehiscence of an anther to release the pollen grains contained within it. go-plus.json http://purl.obolibrary.org/obo/GO_0009901 CHEBI:1171 biolink:ChemicalSubstance 2-hydroxypropylphosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1171 GO:0009902 biolink:BiologicalProcess chloroplast relocation The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery. go-plus.json chloroplast movement http://purl.obolibrary.org/obo/GO_0009902 CHEBI:23527 biolink:ChemicalSubstance cytochalasin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_23527 chebi_ph7_3 GO:0009903 biolink:BiologicalProcess chloroplast avoidance movement The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery. go-plus.json high-fluence-rate response http://purl.obolibrary.org/obo/GO_0009903 GO:0009904 biolink:BiologicalProcess chloroplast accumulation movement The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis. go-plus.json low-fluence-rate response http://purl.obolibrary.org/obo/GO_0009904 GO:0009905 biolink:MolecularActivity ent-copalyl diphosphate synthase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate. EC:5.5.1.13|KEGG_REACTION:R02068|RHEA:14841|MetaCyc:5.5.1.13-RXN go-plus.json ent-kaurene synthetase A activity|ent-copalyl-diphosphate lyase (decyclizing)|ent-kaurene synthase A activity|diterpene cyclase activity http://purl.obolibrary.org/obo/GO_0009905 GO:0009906 biolink:BiologicalProcess response to photoperiod, blue light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. go-plus.json http://purl.obolibrary.org/obo/GO_0009906 NCBITaxon:68336 biolink:OrganismalEntity Bacteroidetes/Chlorobi group go-plus.json CFB/Green sulfur bacteria group|CFB/Chlorobi group|Cytophagales/Green sulfur bacteria group http://purl.obolibrary.org/obo/NCBITaxon_68336 CHEBI:1148 biolink:ChemicalSubstance 2-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1148 CHEBI:23503 biolink:ChemicalSubstance 4-amino-1,2-oxazolidin-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_23503 CHEBI:23500 biolink:ChemicalSubstance cyclopropanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_23500 UBERON:0004792 biolink:AnatomicalEntity secretion of endocrine pancreas A secretion that is part of a endocrine pancreas [Automatically generated definition]. go-plus.json endocrine pancreas secretion|pars endocrina pancreatis secretion|pancreatic endocrine secretion|secretion of pars endocrina pancreatis http://purl.obolibrary.org/obo/UBERON_0004792 UBERON:0004793 biolink:AnatomicalEntity secretion of exocrine pancreas A secretion that is part of a exocrine pancreas [Automatically generated definition]. go-plus.json pancreatic exocrine secretion|secretion of pars exocrina pancreatis|pars exocrina pancreatis secretion|exocrine pancreas secretion http://purl.obolibrary.org/obo/UBERON_0004793 CHEBI:1156 biolink:ChemicalSubstance 2-hydroxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_1156 chebi_ph7_3 UBERON:0004790 biolink:AnatomicalEntity skin mucous gland A mucous gland that is part of the skin. go-plus.json mucous gland of entire skin|skin of body mucous gland|mucous gland of skin of body|skin mucus gland http://purl.obolibrary.org/obo/UBERON_0004790 CHEBI:1157 biolink:ChemicalSubstance isethionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1157 UBERON:0004791 biolink:AnatomicalEntity thymus trabecula the thymic connective tissue which extends into the parenchyma go-plus.json thymus gland trabecula|trabecula of thymus|thymic trabecula|trabecula of thymus gland http://purl.obolibrary.org/obo/UBERON_0004791 CHEBI:1159 biolink:ChemicalSubstance 2-hydroxyethylphosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_1159 CHEBI:23505 biolink:ChemicalSubstance cystathionines go-plus.json http://purl.obolibrary.org/obo/CHEBI_23505 UBERON:0004796 biolink:AnatomicalEntity prostate gland secretion A bodily secretion that is produced by the prostate gland. go-plus.json prostate fluid|secretion of prostate|prostatic fluid|prostate secretion|secretion of prostate gland http://purl.obolibrary.org/obo/UBERON_0004796 UBERON:0004797 biolink:AnatomicalEntity blood vessel layer Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia. go-plus.json http://purl.obolibrary.org/obo/UBERON_0004797 UBERON:0004794 biolink:AnatomicalEntity esophagus secretion A secretion that is part of a esophagus [Automatically generated definition]. go-plus.json oesophagus secretion|secretion of gullet|secretion of esophagus|gullet secretion|secretion of oesophagus|esophageal secretion http://purl.obolibrary.org/obo/UBERON_0004794 CHEBI:23509 biolink:ChemicalSubstance cysteine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_23509 UBERON:0004795 biolink:AnatomicalEntity pancreas secretion A secretion that is part of a pancreas [Automatically generated definition]. go-plus.json pancreatic secretion|secretion of pancreas http://purl.obolibrary.org/obo/UBERON_0004795 UBERON:0011591 biolink:AnatomicalEntity tract of diencephalon An axon tract that is part of a diencephalon. go-plus.json diencephalon tract http://purl.obolibrary.org/obo/UBERON_0011591 UBERON:0011590 biolink:AnatomicalEntity commissure of diencephalon A commissure that is part of a diencephalon. go-plus.json diencephalon commissure http://purl.obolibrary.org/obo/UBERON_0011590 UBERON:0011595 biolink:AnatomicalEntity jaw region A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011595 UBERON:0011594 biolink:AnatomicalEntity dentary tooth Tooth that is attached to a dentary/mandible[TAO,modified]. go-plus.json tooth of dentary|mandibular teeth|mandibular tooth http://purl.obolibrary.org/obo/UBERON_0011594 UBERON:0011593 biolink:AnatomicalEntity maxillary tooth A tooth that is attached to a maxilla[TAO,modified]. go-plus.json maxillary teeth http://purl.obolibrary.org/obo/UBERON_0011593 UBERON:0011592 biolink:AnatomicalEntity future upper lip go-plus.json upper jaw future lip http://purl.obolibrary.org/obo/UBERON_0011592 UBERON:0011597 biolink:AnatomicalEntity bone of upper jaw Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species). go-plus.json upper jaw bone http://purl.obolibrary.org/obo/UBERON_0011597 UBERON:0011596 biolink:AnatomicalEntity future lower lip go-plus.json lower jaw future lip http://purl.obolibrary.org/obo/UBERON_0011596 UBERON:0011589 biolink:AnatomicalEntity non-mineralized cartilage tissue Cartilage tissue that is not mineralized. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011589 CHEBI:38522 biolink:ChemicalSubstance pyrrolizines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38522 CHEBI:38526 biolink:ChemicalSubstance quinolizidine alkaloid fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_38526 CHEBI:38521 biolink:ChemicalSubstance pyrrolizine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38521 UBERON:0035570 biolink:AnatomicalEntity tectothalamic tract go-plus.json tectothalamic tract|tectothalamic pathway|tectothalamic fibers|tectothalamic fibers|ttp http://purl.obolibrary.org/obo/UBERON_0035570 UBERON:0011584 biolink:AnatomicalEntity zeugopodial skeleton Section of the forelimb skeleton located between the stylopodium and the autopodium. go-plus.json zygopodium|zeugopod skeleton|mesomere 2 skeleton|epipodium|mesomere 2|skeleton of zeugopod|epipodial skeleton http://purl.obolibrary.org/obo/UBERON_0011584 UBERON:0011583 biolink:AnatomicalEntity stylopodial skeleton Proximal element of a free limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively[VSAO, modified]. go-plus.json stylopodium skeleton|stylopodium|proximal metapterygial mesomere|propodial skeleton|mesomere 1|stylopod|propodium http://purl.obolibrary.org/obo/UBERON_0011583 UBERON:0011582 biolink:AnatomicalEntity paired limb/fin skeleton The collection of all skeletal elements in an individual limb or fin. go-plus.json skeletal parts of limb/fin|skeleton of limb/fin|limb/fin skeleton http://purl.obolibrary.org/obo/UBERON_0011582 UBERON:0011588 biolink:AnatomicalEntity pre-enamel Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix. go-plus.json pre-enamel tissue|preenamel tissue http://purl.obolibrary.org/obo/UBERON_0011588 UBERON:0011587 biolink:AnatomicalEntity pre-dentine Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix. go-plus.json pre-dentine tissue|predentine tissue|predentin http://purl.obolibrary.org/obo/UBERON_0011587 UBERON:0011585 biolink:AnatomicalEntity cell condensation Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). go-plus.json http://purl.obolibrary.org/obo/UBERON_0011585 CHEBI:38532 biolink:ChemicalSubstance hydrazone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38532 CHEBI:38530 biolink:ChemicalSubstance quinazolines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38530 CHEBI:63510 biolink:ChemicalSubstance EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63510 UBERON:0011574 biolink:AnatomicalEntity mesonephric duct lumen A tube lumen that is part of a mesonephric duct. go-plus.json cavity of nephric duct|nephric duct lumen http://purl.obolibrary.org/obo/UBERON_0011574 CHEBI:38503 biolink:ChemicalSubstance EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38503 CHEBI:38500 biolink:ChemicalSubstance EC 1.9.3.1 (cytochrome c oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38500 UBERON:0035597 biolink:AnatomicalEntity profundal placode An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24. go-plus.json ophthalmic lobe of trigeminal placode complex|profundus placode|ophthalmic lobe of trigeminal placode|ophthalmic placode http://purl.obolibrary.org/obo/UBERON_0035597 UBERON:0011566 biolink:AnatomicalEntity lumen of esophagus An anatomical cavity that is part of a esophagus. go-plus.json cavity of eosophagus|esophageal lumen|cavity of esophagus|eosophageal lumen|eosophagus lumen|eosophageal cavity|esophagus lumen|esophageal cavity http://purl.obolibrary.org/obo/UBERON_0011566 UBERON:0011565 biolink:AnatomicalEntity lumen of gastrointestinal system go-plus.json gastrointestinal tract lumen|cavity of gastrointestinal tract|cavity of digestive tract|lumen of gastrointestinal tract http://purl.obolibrary.org/obo/UBERON_0011565 CHEBI:63525 biolink:ChemicalSubstance D-mannosyl-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63525 CHEBI:63524 biolink:ChemicalSubstance 5-hydroxyectoinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63524 CHEBI:63523 biolink:ChemicalSubstance fructosyllysinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63523 CHEBI:38512 biolink:ChemicalSubstance dibenzoquinolizine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38512 CHEBI:38518 biolink:ChemicalSubstance benzophenanthridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38518 CHEBI:63529 biolink:ChemicalSubstance guanyl deoxyribonucleotide oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63529 CHEBI:38517 biolink:ChemicalSubstance benzophenanthridine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38517 CHEBI:63528 biolink:ChemicalSubstance dTMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63528 chebi_ph7_3 CHEBI:63527 biolink:ChemicalSubstance TTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63527 chebi_ph7_3 CHEBI:38515 biolink:ChemicalSubstance isoquinoline alkaloid fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_38515 CHEBI:63526 biolink:ChemicalSubstance platinum cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_63526 UBERON:0035523 biolink:AnatomicalEntity anterior surface of prostate The aspect of the prostate facing the pubic symphysis. go-plus.json anterior surface of prostate gland|facies anterior (prostatae)|facies anterior prostatae http://purl.obolibrary.org/obo/UBERON_0035523 CHEBI:63534 biolink:ChemicalSubstance monoamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63534 CHEBI:87504 biolink:ChemicalSubstance (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87504 chebi_ph7_3 CHEBI:87507 biolink:ChemicalSubstance (4Z)-2-oxohept-4-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87507 chebi_ph7_3 CHEBI:63539 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63539 CHEBI:87509 biolink:ChemicalSubstance (2R,3E)-5-oxopent-3-ene-1,2,5-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87509 NCBITaxon:2206 biolink:OrganismalEntity Methanosarcinaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2206 NCBITaxon:2024747 biolink:OrganismalEntity Dactyloidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2024747 CHEBI:63543 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63543 NCBITaxon:2207 biolink:OrganismalEntity Methanosarcina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2207 CHEBI:63542 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63542 CHEBI:63541 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63541 CHEBI:63540 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63540 CHEBI:63547 biolink:ChemicalSubstance 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63547 CHEBI:63546 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63546 CHEBI:63545 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63545 CHEBI:63544 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63544 UBERON:0035529 biolink:AnatomicalEntity left common iliac artery go-plus.json trunk of left common iliac arterial tree http://purl.obolibrary.org/obo/UBERON_0035529 CHEBI:63548 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63548 CHEBI:63550 biolink:ChemicalSubstance TTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_63550 CHEBI:63553 biolink:ChemicalSubstance 2-hydroxy-1-phenyl-1-propanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_63553 chebi_ph7_3 UBERON:0035546 biolink:AnatomicalEntity uveal vein go-plus.json ciliary vein http://purl.obolibrary.org/obo/UBERON_0035546 CHEBI:63552 biolink:ChemicalSubstance 1-phenyl-1,2-propanedione go-plus.json http://purl.obolibrary.org/obo/CHEBI_63552 chebi_ph7_3 UBERON:0035545 biolink:AnatomicalEntity deep lymphatic vessel The tubules that carry lymph throughout the body that are in the interior of the body or limbs. go-plus.json deep lymph vessel http://purl.obolibrary.org/obo/UBERON_0035545 CHEBI:63551 biolink:ChemicalSubstance carbohydrate acid derivative anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63551 CHEBI:87522 biolink:ChemicalSubstance (S)-4-hydroxy-2-oxoheptanedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87522 chebi_ph7_3 CHEBI:63558 biolink:ChemicalSubstance DIBOA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63558 chebi_ph7_3 UBERON:0035539 biolink:AnatomicalEntity esophageal artery Any of several arteries that arise from the aorta and supply blood to the esophagus. go-plus.json oesophageal artery|aortic esophageal artery http://purl.obolibrary.org/obo/UBERON_0035539 CHEBI:63559 biolink:ChemicalSubstance HBOA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63559 chebi_ph7_3 UBERON:0035551 biolink:AnatomicalEntity deep vasculature The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin. go-plus.json deep part of circulatory system http://purl.obolibrary.org/obo/UBERON_0035551 CHEBI:63561 biolink:ChemicalSubstance ketoaldonate derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63561 UBERON:0035550 biolink:AnatomicalEntity superficial vein Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers. go-plus.json superficial veins|superficial vessels|superfical vein http://purl.obolibrary.org/obo/UBERON_0035550 UBERON:0035553 biolink:AnatomicalEntity left cardiac chamber Any chamber of the left side of the heart go-plus.json http://purl.obolibrary.org/obo/UBERON_0035553 UBERON:0035552 biolink:AnatomicalEntity deep vein A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery. go-plus.json deep veins|deep vessels http://purl.obolibrary.org/obo/UBERON_0035552 UBERON:0035555 biolink:AnatomicalEntity lateral line sense organ go-plus.json http://purl.obolibrary.org/obo/UBERON_0035555 UBERON:0035554 biolink:AnatomicalEntity right cardiac chamber Any chamber of the right side of the heart go-plus.json http://purl.obolibrary.org/obo/UBERON_0035554 CHEBI:63563 biolink:ChemicalSubstance oligosaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63563 UBERON:0035548 biolink:AnatomicalEntity colic artery go-plus.json http://purl.obolibrary.org/obo/UBERON_0035548 CHEBI:63567 biolink:ChemicalSubstance tetrasaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63567 UBERON:0035549 biolink:AnatomicalEntity vasculature of integument The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin. go-plus.json vasculature of skin|hypodermis vasculature|skin vasculature|subcutaneous vasculature|superficial vasculature|dermis vasculature|superficial part of circulatory system http://purl.obolibrary.org/obo/UBERON_0035549 CHEBI:63566 biolink:ChemicalSubstance pentasaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63566 CHEBI:87518 biolink:ChemicalSubstance ADP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87518 NCBITaxon:2236 biolink:OrganismalEntity Halobacteriaceae go-plus.json Haloarchaeaceae http://purl.obolibrary.org/obo/NCBITaxon_2236 NCBITaxon:2239 biolink:OrganismalEntity Halobacterium go-plus.json Flavobacterium (subgen. Halobacterium)|Halobacter|Haloarchaeum http://purl.obolibrary.org/obo/NCBITaxon_2239 NCBITaxon:2235 biolink:OrganismalEntity Halobacteriales go-plus.json Haloarchaeales http://purl.obolibrary.org/obo/NCBITaxon_2235 GO:1903349 biolink:CellularComponent omegasome membrane Any membrane that is part of an omegasome. go-plus.json http://purl.obolibrary.org/obo/GO_1903349 GO:1903348 biolink:BiologicalProcess positive regulation of bicellular tight junction assembly Any process that activates or increases the frequency, rate or extent of tight junction assembly. go-plus.json up-regulation of tight junction formation|activation of tight junction formation|up-regulation of tight junction assembly|upregulation of tight junction assembly|positive regulation of tight junction formation|up regulation of tight junction formation|up regulation of tight junction assembly|activation of tight junction assembly|upregulation of tight junction formation http://purl.obolibrary.org/obo/GO_1903348 GO:1903347 biolink:BiologicalProcess negative regulation of bicellular tight junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. go-plus.json down-regulation of tight junction assembly|inhibition of tight junction assembly|down-regulation of tight junction formation|negative regulation of tight junction formation|down regulation of tight junction assembly|downregulation of tight junction formation|downregulation of tight junction assembly|down regulation of tight junction formation|inhibition of tight junction formation http://purl.obolibrary.org/obo/GO_1903347 GO:1903346 biolink:BiologicalProcess positive regulation of protein polyglycylation Any process that activates or increases the frequency, rate or extent of protein polyglycylation. go-plus.json up regulation of protein polyglycylation|activation of protein polyglycylation|up-regulation of protein polyglycylation|upregulation of protein polyglycylation http://purl.obolibrary.org/obo/GO_1903346 GO:1903345 biolink:BiologicalProcess negative regulation of protein polyglycylation Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation. go-plus.json down-regulation of protein polyglycylation|inhibition of protein polyglycylation|down regulation of protein polyglycylation|downregulation of protein polyglycylation http://purl.obolibrary.org/obo/GO_1903345 UBERON:0011510 biolink:AnatomicalEntity cloacal bursa An evagination of the cloaca. In Testudines these are hypothesized to function in different physiological roles, primarily in respiration. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011510 CHEBI:133618 biolink:ChemicalSubstance leukotriene F4(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133618 chebi_ph7_3 GO:1903344 biolink:BiologicalProcess regulation of protein polyglycylation Any process that modulates the frequency, rate or extent of protein polyglycylation. go-plus.json http://purl.obolibrary.org/obo/GO_1903344 GO:1903343 biolink:BiologicalProcess positive regulation of meiotic DNA double-strand break formation Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation. go-plus.json upregulation of meiotic DNA double-strand break formation|up regulation of meiotic DNA double-strand break formation|activation of meiotic DNA double-strand break formation|up-regulation of meiotic DNA double-strand break formation http://purl.obolibrary.org/obo/GO_1903343 GO:1903353 biolink:BiologicalProcess regulation of nucleus organization Any process that modulates the frequency, rate or extent of nucleus organization. go-plus.json regulation of nucleus organization and biogenesis|regulation of nuclear organisation|regulation of nuclear morphology|regulation of nuclear organization and biogenesis|regulation of nuclear organization http://purl.obolibrary.org/obo/GO_1903353 GO:1903352 biolink:BiologicalProcess L-ornithine transmembrane transport The directed movement of L-ornithine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903352 GO:1903351 biolink:BiologicalProcess cellular response to dopamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903351 GO:1903350 biolink:BiologicalProcess response to dopamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903350 CHEBI:7101 biolink:ChemicalSubstance N(5)-[(Z)-amino(hydroxyimino)methyl]ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7101 NCBITaxon:2242 biolink:OrganismalEntity Halobacterium salinarum go-plus.json Halobacterium piscisalsi|Pseudomonas salinaria|Bacillus halobius ruber|Halobacterium cutirubrum|Serratia salinaria|Halobacterium salinarium|Halobacter salinaria|Flavobacterium (subgen. Halobacterium) halobium|Bacterium halobium|Serratia cutirubrum|Halobacterium halobium|Flavobacterium (subgen. Halobacterium) salinarium http://purl.obolibrary.org/obo/NCBITaxon_2242 GO:1903359 biolink:BiologicalProcess lateral cortical node assembly The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node. go-plus.json lateral cortical node formation|Skb1-containing cortical node formation|Skb1-containing cortical node assembly http://purl.obolibrary.org/obo/GO_1903359 GO:1903358 biolink:BiologicalProcess regulation of Golgi organization Any process that modulates the frequency, rate or extent of Golgi organization. go-plus.json regulation of Golgi organisation|regulation of Golgi organization and biogenesis http://purl.obolibrary.org/obo/GO_1903358 GO:1903357 biolink:BiologicalProcess regulation of transcription initiation from RNA polymerase I promoter Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter. go-plus.json regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript http://purl.obolibrary.org/obo/GO_1903357 GO:1903356 biolink:BiologicalProcess positive regulation of distal tip cell migration Any process that activates or increases the frequency, rate or extent of distal tip cell migration. go-plus.json up-regulation of distal tip cell migration|upregulation of distal tip cell migration|up regulation of distal tip cell migration|activation of distal tip cell migration http://purl.obolibrary.org/obo/GO_1903356 GO:1903355 biolink:BiologicalProcess negative regulation of distal tip cell migration Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration. go-plus.json inhibition of distal tip cell migration|down regulation of distal tip cell migration|downregulation of distal tip cell migration|down-regulation of distal tip cell migration http://purl.obolibrary.org/obo/GO_1903355 GO:1903354 biolink:BiologicalProcess regulation of distal tip cell migration Any process that modulates the frequency, rate or extent of distal tip cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_1903354 GO:1903364 biolink:BiologicalProcess positive regulation of cellular protein catabolic process Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process. go-plus.json positive regulation of cellular protein degradation|up regulation of cellular protein degradation|up regulation of cellular protein catabolism|activation of cellular protein catabolism|positive regulation of cyclin catabolism|positive regulation of cellular protein breakdown|positive regulation of cellular protein catabolism|up regulation of cellular protein breakdown|up regulation of cellular protein catabolic process|upregulation of cellular protein degradation|up-regulation of cellular protein catabolism|positive regulation of cyclin degradation|upregulation of cellular protein breakdown|up-regulation of cellular protein degradation|upregulation of cellular protein catabolic process|activation of cellular protein degradation|positive regulation of cyclin breakdown|upregulation of cellular protein catabolism|activation of cellular protein breakdown|up-regulation of cellular protein breakdown|positive regulation of degradation of cyclin|positive regulation of cyclin catabolic process|activation of cellular protein catabolic process|up-regulation of cellular protein catabolic process http://purl.obolibrary.org/obo/GO_1903364 GO:1903363 biolink:BiologicalProcess negative regulation of cellular protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process. go-plus.json downregulation of cellular protein catabolism|negative regulation of degradation of cyclin|negative regulation of cellular protein breakdown|down-regulation of cellular protein breakdown|downregulation of cellular protein degradation|down-regulation of cellular protein catabolic process|negative regulation of cyclin catabolism|down-regulation of cellular protein catabolism|negative regulation of cellular protein catabolism|down regulation of cellular protein degradation|downregulation of cellular protein breakdown|inhibition of cellular protein degradation|down regulation of cellular protein breakdown|downregulation of cellular protein catabolic process|negative regulation of cyclin degradation|inhibition of cellular protein catabolism|inhibition of cellular protein breakdown|down regulation of cellular protein catabolic process|negative regulation of cyclin breakdown|inhibition of cellular protein catabolic process|negative regulation of cyclin catabolic process|down regulation of cellular protein catabolism|down-regulation of cellular protein degradation|negative regulation of cellular protein degradation http://purl.obolibrary.org/obo/GO_1903363 GO:1903362 biolink:BiologicalProcess regulation of cellular protein catabolic process Any process that modulates the frequency, rate or extent of cellular protein catabolic process. go-plus.json regulation of cyclin catabolic process|regulation of cellular protein degradation|regulation of cellular protein breakdown|regulation of degradation of cyclin|regulation of cyclin degradation|regulation of cyclin breakdown|regulation of cellular protein catabolism|regulation of cyclin catabolism http://purl.obolibrary.org/obo/GO_1903362 GO:1903361 biolink:BiologicalProcess protein localization to basolateral plasma membrane Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane. go-plus.json protein localisation to basolateral plasma membrane|basolateral protein localization|protein localization in basolateral plasma membrane|protein localisation in basolateral plasma membrane http://purl.obolibrary.org/obo/GO_1903361 GO:1903360 biolink:BiologicalProcess protein localization to lateral cortical node A process in which a protein is transported to, or maintained in, a location within a lateral cortical node. go-plus.json protein localisation to lateral cortical node|protein localization in lateral cortical node|protein localisation in lateral cortical node http://purl.obolibrary.org/obo/GO_1903360 NCBITaxon:2214 biolink:OrganismalEntity Methanosarcina acetivorans go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2214 GO:1903369 biolink:BiologicalProcess negative regulation of foraging behavior Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior. go-plus.json down regulation of foraging behavior|downregulation of foraging behavior|down-regulation of foraging behavior|inhibition of foraging behavior http://purl.obolibrary.org/obo/GO_1903369 GO:1903368 biolink:BiologicalProcess regulation of foraging behavior Any process that modulates the frequency, rate or extent of foraging behavior. go-plus.json http://purl.obolibrary.org/obo/GO_1903368 GO:1903367 biolink:BiologicalProcess positive regulation of fear response Any process that activates or increases the frequency, rate or extent of fear response. go-plus.json up-regulation of fear response|up regulation of physiological fear response|activation of physiological fear response|positive regulation of physiological fear response|upregulation of fear response|up-regulation of physiological fear response|up regulation of fear response|activation of fear response|upregulation of physiological fear response http://purl.obolibrary.org/obo/GO_1903367 GO:1903366 biolink:BiologicalProcess negative regulation of fear response Any process that stops, prevents or reduces the frequency, rate or extent of fear response. go-plus.json downregulation of physiological fear response|inhibition of fear response|negative regulation of physiological fear response|down-regulation of physiological fear response|down regulation of fear response|inhibition of physiological fear response|downregulation of fear response|down-regulation of fear response|down regulation of physiological fear response http://purl.obolibrary.org/obo/GO_1903366 GO:1903365 biolink:BiologicalProcess regulation of fear response Any process that modulates the frequency, rate or extent of fear response. go-plus.json regulation of physiological fear response http://purl.obolibrary.org/obo/GO_1903365 GO:1903375 biolink:BiologicalProcess facioacoustic ganglion development The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. go-plus.json facio-acoustic VII-VIII ganglion complex development|acousticofacial ganglion development|acoustico-facial VII-VIII ganglion complex development|facio-acoustic ganglion development|facio-acoustic ganglion complex VII-VIII development http://purl.obolibrary.org/obo/GO_1903375 GO:1903374 biolink:BiologicalProcess subarachnoid space development The process whose specific outcome is the progression of a subarachnoid space over time, from its formation to the mature structure. go-plus.json subarachnoid cavity development|spatium subarachnoideum development|cavitas subarachnoidea development|cavum subarachnoideale development|spatium leptomeningeum development http://purl.obolibrary.org/obo/GO_1903374 GO:1903373 biolink:BiologicalProcess positive regulation of endoplasmic reticulum tubular network organization Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization. go-plus.json upregulation of endoplasmic reticulum tubular network organization|up-regulation of endoplasmic reticulum tubular network organisation|activation of endoplasmic reticulum tubular network organisation|up regulation of ER tubular network organization|positive regulation of ER tubular network organization|activation of ER tubular network organization|up-regulation of endoplasmic reticulum tubular network organization|activation of endoplasmic reticulum tubular network organization|up-regulation of ER tubular network organisation|positive regulation of endoplasmic reticulum tubular network organisation|up regulation of endoplasmic reticulum tubular network organisation|up-regulation of ER tubular network organization|upregulation of ER tubular network organisation|up regulation of endoplasmic reticulum tubular network organization|upregulation of endoplasmic reticulum tubular network organisation|upregulation of ER tubular network organization|up regulation of ER tubular network organisation|activation of ER tubular network organisation|positive regulation of ER tubular network organisation http://purl.obolibrary.org/obo/GO_1903373 GO:1903372 biolink:BiologicalProcess negative regulation of endoplasmic reticulum tubular network organization Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization. go-plus.json downregulation of ER tubular network organization|down-regulation of ER tubular network organisation|negative regulation of ER tubular network organisation|down-regulation of endoplasmic reticulum tubular network organisation|negative regulation of endoplasmic reticulum tubular network organisation|negative regulation of ER tubular network organization|inhibition of ER tubular network organisation|down-regulation of ER tubular network organization|down-regulation of endoplasmic reticulum tubular network organization|inhibition of ER tubular network organization|downregulation of endoplasmic reticulum tubular network organisation|down regulation of ER tubular network organisation|down regulation of endoplasmic reticulum tubular network organisation|inhibition of endoplasmic reticulum tubular network organisation|downregulation of endoplasmic reticulum tubular network organization|downregulation of ER tubular network organisation|down regulation of endoplasmic reticulum tubular network organization|down regulation of ER tubular network organization|inhibition of endoplasmic reticulum tubular network organization http://purl.obolibrary.org/obo/GO_1903372 GO:1903371 biolink:BiologicalProcess regulation of endoplasmic reticulum tubular network organization Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization. go-plus.json regulation of endoplasmic reticulum tubular network organisation|regulation of ER tubular network organisation|regulation of ER tubular network organization http://purl.obolibrary.org/obo/GO_1903371 GO:1903370 biolink:BiologicalProcess positive regulation of foraging behavior Any process that activates or increases the frequency, rate or extent of foraging behavior. go-plus.json up-regulation of foraging behavior|upregulation of foraging behavior|up regulation of foraging behavior|activation of foraging behavior http://purl.obolibrary.org/obo/GO_1903370 CHEBI:38582 biolink:ChemicalSubstance difluorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38582 CHEBI:38584 biolink:ChemicalSubstance 1,3-difluorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38584 chebi_ph7_3 CHEBI:133603 biolink:ChemicalSubstance methanesulfinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133603 chebi_ph7_3 CHEBI:133606 biolink:ChemicalSubstance 1-octadecanoyl-2-arachidonoyl-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133606 chebi_ph7_3 GO:1903379 biolink:BiologicalProcess regulation of mitotic chromosome condensation Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. go-plus.json http://purl.obolibrary.org/obo/GO_1903379 GO:1903378 biolink:BiologicalProcess positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. go-plus.json positive regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron apoptosis in response to oxidative stress|activation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|activation of neuron apoptosis in response to oxidative stress|positive regulation of neuron apoptosis in response to oxidative stress|up regulation of neuron apoptosis in response to oxidative stress|up regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of neuron apoptosis in response to oxidative stress|upregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903378 GO:1903377 biolink:BiologicalProcess negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. go-plus.json negative regulation of oxidative stress-induced neuron apoptosis|negative regulation of neuron apoptosis in response to oxidative stress|down-regulation of neuron apoptosis in response to oxidative stress|down-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|protection against oxidative stress-induced neuronal apoptosis|downregulation of neuron apoptosis in response to oxidative stress|downregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|neuroprotection against oxidative stress-induced apoptosis|protection against oxidative stress-induced neuron apoptosis|down regulation of neuron apoptosis in response to oxidative stress|down regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of neuron apoptosis in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903377 GO:1903376 biolink:BiologicalProcess regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. go-plus.json regulation of oxidative stress-induced neuron apoptosis|regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|regulation of neuron apoptosis in response to oxidative stress|regulation of oxidative stress-induced neuronal apoptosis http://purl.obolibrary.org/obo/GO_1903376 GO:1903386 biolink:BiologicalProcess negative regulation of homophilic cell adhesion Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion. go-plus.json downregulation of homophilic cell adhesion|down regulation of homophilic cell adhesion|inhibition of homophilic cell adhesion|down-regulation of homophilic cell adhesion http://purl.obolibrary.org/obo/GO_1903386 GO:1903385 biolink:BiologicalProcess regulation of homophilic cell adhesion Any process that modulates the frequency, rate or extent of homophilic cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_1903385 GO:1903384 biolink:BiologicalProcess negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway. go-plus.json down regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of neuron apoptosis in response to hydrogen peroxide|down regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|downregulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|protection against hydrogen peroxide-induced neuron apoptosis|inhibition of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|inhibition of neuron intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron apoptosis in response to hydrogen peroxide|negative regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|negative regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of neuron apoptosis in response to hydrogen peroxide|downregulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of H2O2-induced neuron intrinsic apoptotic signaling pathway|protection against H2O2-induced neuron apoptosis|down-regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2 http://purl.obolibrary.org/obo/GO_1903384 GO:1903383 biolink:BiologicalProcess regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway. go-plus.json regulation of hydrogen peroxide-induced neuron apoptosis|regulation of neuron apoptosis in response to hydrogen peroxide|regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|regulation of H2O2-induced neuron apoptosis|regulation of hydrogen peroxide-induced neuronal apoptosis http://purl.obolibrary.org/obo/GO_1903383 CHEBI:38599 biolink:ChemicalSubstance 4H-pyrazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38599 chebi_ph7_3 GO:1903382 biolink:BiologicalProcess negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway. go-plus.json inhibition of ER stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|inhibition of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1903382 GO:1903381 biolink:BiologicalProcess regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway. go-plus.json regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of ER stress-induced neuron apoptosis|regulation of endoplasmic reticulum stress-induced neuron apoptosis|regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1903381 GO:1903380 biolink:BiologicalProcess positive regulation of mitotic chromosome condensation Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. go-plus.json up-regulation of mitotic chromosome condensation|upregulation of mitotic chromosome condensation|up regulation of mitotic chromosome condensation|activation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_1903380 CHEBI:38597 biolink:ChemicalSubstance triazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38597 CHEBI:38596 biolink:ChemicalSubstance pyrazolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38596 CHEBI:38595 biolink:ChemicalSubstance 3H-pyrazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38595 chebi_ph7_3 NCBITaxon:2276 biolink:OrganismalEntity Pyrobaculum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2276 GO:1903389 biolink:BiologicalProcess negative regulation of synaptic vesicle uncoating Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating. go-plus.json down regulation of synaptic vesicle uncoating|inhibition of synaptic vesicle uncoating|negative regulation of synaptic vesicle coat depolymerization|down-regulation of synaptic vesicle coat depolymerization|negative regulation of synaptic vesicle coat protein depolymerization|down-regulation of synaptic vesicle coat protein depolymerization|downregulation of synaptic vesicle coat depolymerization|downregulation of synaptic vesicle coat protein depolymerization|down regulation of synaptic vesicle coat depolymerization|down-regulation of synaptic vesicle uncoating|inhibition of synaptic vesicle coat depolymerization|down regulation of synaptic vesicle coat protein depolymerization|inhibition of synaptic vesicle coat protein depolymerization|downregulation of synaptic vesicle uncoating http://purl.obolibrary.org/obo/GO_1903389 GO:1903388 biolink:BiologicalProcess regulation of synaptic vesicle uncoating Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating. go-plus.json regulation of synaptic vesicle coat depolymerization|regulation of synaptic vesicle coat protein depolymerization http://purl.obolibrary.org/obo/GO_1903388 GO:1903387 biolink:BiologicalProcess positive regulation of homophilic cell adhesion Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion. go-plus.json up regulation of homophilic cell adhesion|upregulation of homophilic cell adhesion|up-regulation of homophilic cell adhesion|activation of homophilic cell adhesion http://purl.obolibrary.org/obo/GO_1903387 GO:1903397 biolink:BiologicalProcess positive regulation of secondary cell septum biogenesis Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis. go-plus.json up regulation of secondary cell septum biogenesis|upregulation of secondary cell septum biogenesis|up-regulation of secondary cell septum biogenesis|activation of secondary cell septum biogenesis http://purl.obolibrary.org/obo/GO_1903397 GO:1903396 biolink:BiologicalProcess negative regulation of secondary cell septum biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis. go-plus.json downregulation of secondary cell septum biogenesis|down regulation of secondary cell septum biogenesis|inhibition of secondary cell septum biogenesis|down-regulation of secondary cell septum biogenesis http://purl.obolibrary.org/obo/GO_1903396 GO:1903395 biolink:BiologicalProcess regulation of secondary cell septum biogenesis Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1903395 GO:1903394 biolink:BiologicalProcess protein localization to kinetochore involved in kinetochore assembly Any protein localization to kinetochore that is involved in kinetochore assembly. go-plus.json condensin localization to kinetochore involved in kinetochore formation|condensin localization to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in kinetochore assembly|protein localization to kinetochore involved in centromere/kinetochore complex maturation|condensin localization to kinetochore involved in chromosome-kinetochore attachment|protein localization to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in centromere/kinetochore complex maturation|condensin localization to kinetochore involved in kinetochore assembly|protein localisation to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in chromosome-kinetochore attachment|condensin localization to kinetochore involved in centromere/kinetochore complex maturation|protein localisation to kinetochore involved in chromosome-kinetochore attachment http://purl.obolibrary.org/obo/GO_1903394 GO:1903393 biolink:BiologicalProcess positive regulation of adherens junction organization Any process that activates or increases the frequency, rate or extent of adherens junction organization. go-plus.json positive regulation of adherens junction organisation|up regulation of adherens junction organisation|up regulation of adherens junction organization|positive regulation of adherens junction assembly and maintenance|up regulation of adherens junction assembly and maintenance|upregulation of adherens junction organisation|upregulation of adherens junction organization|up-regulation of adherens junction organisation|activation of adherens junction organisation|upregulation of adherens junction assembly and maintenance|up-regulation of adherens junction organization|activation of adherens junction organization|up-regulation of adherens junction assembly and maintenance|activation of adherens junction assembly and maintenance http://purl.obolibrary.org/obo/GO_1903393 GO:1903392 biolink:BiologicalProcess negative regulation of adherens junction organization Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization. go-plus.json down-regulation of adherens junction organization|downregulation of adherens junction organisation|negative regulation of adherens junction assembly and maintenance|down-regulation of adherens junction assembly and maintenance|down regulation of adherens junction organisation|inhibition of adherens junction organisation|downregulation of adherens junction organization|downregulation of adherens junction assembly and maintenance|down regulation of adherens junction organization|inhibition of adherens junction organization|down regulation of adherens junction assembly and maintenance|inhibition of adherens junction assembly and maintenance|negative regulation of adherens junction organisation|down-regulation of adherens junction organisation http://purl.obolibrary.org/obo/GO_1903392 CHEBI:14597 biolink:ChemicalSubstance methylarsonite go-plus.json http://purl.obolibrary.org/obo/CHEBI_14597 GO:1903391 biolink:BiologicalProcess regulation of adherens junction organization Any process that modulates the frequency, rate or extent of adherens junction organization. go-plus.json regulation of adherens junction organisation|regulation of adherens junction assembly and maintenance http://purl.obolibrary.org/obo/GO_1903391 GO:1903390 biolink:BiologicalProcess positive regulation of synaptic vesicle uncoating Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating. go-plus.json upregulation of synaptic vesicle coat depolymerization|upregulation of synaptic vesicle coat protein depolymerization|up regulation of synaptic vesicle uncoating|up-regulation of synaptic vesicle coat depolymerization|activation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle coat protein depolymerization|activation of synaptic vesicle coat protein depolymerization|upregulation of synaptic vesicle uncoating|positive regulation of synaptic vesicle coat depolymerization|up regulation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle uncoating|positive regulation of synaptic vesicle coat protein depolymerization|activation of synaptic vesicle uncoating|up regulation of synaptic vesicle coat protein depolymerization http://purl.obolibrary.org/obo/GO_1903390 CHEBI:38560 biolink:ChemicalSubstance simple protein go-plus.json http://purl.obolibrary.org/obo/CHEBI_38560 NCBITaxon:2281 biolink:OrganismalEntity Sulfolobales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2281 NCBITaxon:2287 biolink:OrganismalEntity Saccharolobus solfataricus go-plus.json Sulfolobus solfataricus http://purl.obolibrary.org/obo/NCBITaxon_2287 GO:1903399 biolink:BiologicalProcess positive regulation of m7G(5')pppN diphosphatase activity Any process that activates or increases the frequency, rate or extent of m7G(5')pppN diphosphatase activity. go-plus.json upregulation of decapase activity|up regulation of M(7)G(5')pppN pyrophosphatase activity|positive regulation of m7G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN diphosphatase activity|upregulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up regulation of decapase activity|upregulation of M(7)G(5')pppN pyrophosphatase activity|positive regulation of decapase activity|upregulation of m7G(5')pppN pyrophosphatase activity|upregulation of m7G(5')pppN diphosphatase activity|up-regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|activation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|activation of decapase activity|up-regulation of M(7)G(5')pppN pyrophosphatase activity|activation of M(7)G(5')pppN pyrophosphatase activity|up-regulation of m7G(5')pppN pyrophosphatase activity|activation of m7G(5')pppN pyrophosphatase activity|up-regulation of m7G(5')pppN diphosphatase activity|up-regulation of decapase activity|activation of m7G(5')pppN diphosphatase activity|positive regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|positive regulation of M(7)G(5')pppN pyrophosphatase activity http://purl.obolibrary.org/obo/GO_1903399 GO:1903398 biolink:BiologicalProcess regulation of m7G(5')pppN diphosphatase activity Any process that modulates the frequency, rate or extent of m7G(5')pppN diphosphatase activity. go-plus.json regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|regulation of M(7)G(5')pppN pyrophosphatase activity|regulation of decapase activity|regulation of m7G(5')pppN pyrophosphatase activity http://purl.obolibrary.org/obo/GO_1903398 CHEBI:38579 biolink:ChemicalSubstance peptide pheromone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38579 CHEBI:38574 biolink:ChemicalSubstance ferriheme go-plus.json http://purl.obolibrary.org/obo/CHEBI_38574 CHEBI:38573 biolink:ChemicalSubstance ferroheme go-plus.json http://purl.obolibrary.org/obo/CHEBI_38573 NCBITaxon:2259 biolink:OrganismalEntity Thermococcaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2259 NCBITaxon:2258 biolink:OrganismalEntity Thermococcales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2258 NCBITaxon:2263 biolink:OrganismalEntity Thermococcus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2263 CHEBI:7125 biolink:ChemicalSubstance 2-acetamido-2-deoxy-D-glucopyranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_7125 NCBITaxon:2266 biolink:OrganismalEntity Thermoproteales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2266 NCBITaxon:2267 biolink:OrganismalEntity Thermoproteaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2267 CHEBI:157662 biolink:ChemicalSubstance N-(omega-linoleoyloxy-ultra-long chain fatty acyl)sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_157662 chebi_ph7_3 CHEBI:133697 biolink:ChemicalSubstance 4-amino-4-de(dimethylamino)anhydrotetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133697 chebi_ph7_3 CHEBI:133696 biolink:ChemicalSubstance desmethylanhydrotetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133696 chebi_ph7_3 CHEBI:157669 biolink:ChemicalSubstance carbocyclic fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_157669 CHEBI:157668 biolink:ChemicalSubstance carbocyclic fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_157668 CHEBI:157663 biolink:ChemicalSubstance N-(omega-hydroxy-ultra-long chain fatty acyl)sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_157663 chebi_ph7_3 CHEBI:87491 biolink:ChemicalSubstance (2R,3E)-5-oxopent-3-ene-1,2,5-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87491 chebi_ph7_3 CHEBI:143018 biolink:ChemicalSubstance ultra-long-chain fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143018 chebi_ph7_3 CHEBI:143017 biolink:ChemicalSubstance ultra-long-chain fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_143017 CHEBI:143005 biolink:ChemicalSubstance ultra-long-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143005 chebi_ph7_3 CHEBI:143004 biolink:ChemicalSubstance ultra-long-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_143004 CHEBI:133673 biolink:ChemicalSubstance glyphosate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133673 chebi_ph7_3 PR:000001240 biolink:Protein motilin receptor A growth hormone secretagogue/motilin receptor that is a translation product of the human MLNR gene or a 1:1 ortholog thereof. The preferred ligand is motilin, an intestinal peptide that stimulates contraction of gut smooth muscle. go-plus.json GPR38|G-protein coupled receptor 38|MTLR|MLNR|MTLR1 http://purl.obolibrary.org/obo/PR_000001240 CHEBI:133674 biolink:ChemicalSubstance (aminomethyl)phosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133674 chebi_ph7_3 PR:000001245 biolink:Protein rhodopsin An animal opsin that is a translation product of the human RHO gene or a 1:1 ortholog thereof. go-plus.json OPN2|opsin-2|RHO http://purl.obolibrary.org/obo/PR_000001245 PR:000001255 biolink:Protein C-C chemokine receptor type 3 A chemokine receptor CCR1/3/1L that is a translation product of the human CCR3 gene or a 1:1 ortholog thereof. go-plus.json CC-CKR-3|Cmkbr1l2|CCR3|CMKBR3|chemokine receptor CCR3|eosinophil eotaxin receptor|CCR-3|macrophage inflammatory protein 1-alpha receptor-like 2|MIP-1 alpha RL2|CD193|CKR3|C-C CKR-3 http://purl.obolibrary.org/obo/PR_000001255 GO:1903309 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903309 GO:1903308 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903308 GO:1903307 biolink:BiologicalProcess positive regulation of regulated secretory pathway Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. go-plus.json up regulation of regulated secretory pathway|activation of regulated secretory pathway|up-regulation of regulated secretory pathway|upregulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_1903307 GO:1903306 biolink:BiologicalProcess negative regulation of regulated secretory pathway Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway. go-plus.json downregulation of regulated secretory pathway|down-regulation of regulated secretory pathway|inhibition of regulated secretory pathway|down regulation of regulated secretory pathway http://purl.obolibrary.org/obo/GO_1903306 GO:1903305 biolink:BiologicalProcess regulation of regulated secretory pathway Any process that modulates the frequency, rate or extent of regulated secretory pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1903305 GO:1903304 biolink:BiologicalProcess positive regulation of pyruvate kinase activity Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity. go-plus.json up-regulation of pyruvate kinase activity|activation of pyruvate kinase activity|up regulation of phosphoenol transphosphorylase activity|activation of phosphoenol transphosphorylase activity|positive regulation of phosphoenol transphosphorylase activity|up-regulation of ATP:pyruvate 2-O-phosphotransferase activity|activation of ATP:pyruvate 2-O-phosphotransferase activity|up-regulation of phosphoenolpyruvate kinase activity|up regulation of pyruvate kinase activity|up-regulation of phosphoenol transphosphorylase activity|positive regulation of ATP:pyruvate 2-O-phosphotransferase activity|upregulation of phosphoenolpyruvate kinase activity|up regulation of ATP:pyruvate 2-O-phosphotransferase activity|upregulation of pyruvate kinase activity|upregulation of phosphoenol transphosphorylase activity|up regulation of phosphoenolpyruvate kinase activity|upregulation of ATP:pyruvate 2-O-phosphotransferase activity|positive regulation of phosphoenolpyruvate kinase activity|activation of phosphoenolpyruvate kinase activity http://purl.obolibrary.org/obo/GO_1903304 GO:1903303 biolink:BiologicalProcess negative regulation of pyruvate kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity. go-plus.json negative regulation of phosphoenolpyruvate kinase activity|down-regulation of phosphoenolpyruvate kinase activity|down-regulation of pyruvate kinase activity|negative regulation of phosphoenol transphosphorylase activity|down-regulation of phosphoenol transphosphorylase activity|inhibition of phosphoenolpyruvate kinase activity|negative regulation of ATP:pyruvate 2-O-phosphotransferase activity|down-regulation of ATP:pyruvate 2-O-phosphotransferase activity|inhibition of phosphoenol transphosphorylase activity|downregulation of pyruvate kinase activity|down regulation of pyruvate kinase activity|down regulation of phosphoenolpyruvate kinase activity|inhibition of pyruvate kinase activity|downregulation of ATP:pyruvate 2-O-phosphotransferase activity|downregulation of phosphoenolpyruvate kinase activity|down regulation of ATP:pyruvate 2-O-phosphotransferase activity|inhibition of ATP:pyruvate 2-O-phosphotransferase activity|down regulation of phosphoenol transphosphorylase activity|downregulation of phosphoenol transphosphorylase activity http://purl.obolibrary.org/obo/GO_1903303 GO:1903302 biolink:BiologicalProcess regulation of pyruvate kinase activity Any process that modulates the frequency, rate or extent of pyruvate kinase activity. go-plus.json regulation of phosphoenolpyruvate kinase activity|regulation of ATP:pyruvate 2-O-phosphotransferase activity|regulation of phosphoenol transphosphorylase activity http://purl.obolibrary.org/obo/GO_1903302 GO:1903301 biolink:BiologicalProcess positive regulation of hexokinase activity Any process that activates or increases the frequency, rate or extent of hexokinase activity. go-plus.json activation of hexokinase type II activity|upregulation of hexokinase type IV glucokinase activity|upregulation of hexokinase type III activity|upregulation of hexokinase type I activity|up regulation of glucose ATP phosphotransferase activity|activation of hexokinase D|up-regulation of hexokinase type IV (glucokinase) activity|up-regulation of hexokinase activity|upregulation of hexokinase type IV|positive regulation of glucose ATP phosphotransferase activity|activation of glucose ATP phosphotransferase activity|up-regulation of hexokinase type II activity|positive regulation of ATP:D-hexose 6-phosphotransferase activity|upregulation of hexokinase (phosphorylating)|positive regulation of hexokinase D|up regulation of ATP:D-hexose 6-phosphotransferase activity|up regulation of ATP-dependent hexokinase activity|up regulation of hexokinase D|up regulation of hexokinase type IV glucokinase activity|up-regulation of hexokinase type I activity|activation of ATP-dependent hexokinase activity|up-regulation of hexokinase type III activity|positive regulation of ATP-dependent hexokinase activity|positive regulation of hexokinase type IV glucokinase activity|activation of hexokinase type IV glucokinase activity|upregulation of hexokinase type IV (glucokinase) activity|up-regulation of hexokinase type IV|upregulation of hexokinase activity|upregulation of hexokinase type II activity|up-regulation of glucose ATP phosphotransferase activity|up-regulation of hexokinase (phosphorylating)|activation of hexokinase type III activity|activation of hexokinase (phosphorylating)|activation of hexokinase type I activity|upregulation of ATP:D-hexose 6-phosphotransferase activity|activation of hexokinase type IV|upregulation of hexokinase D|positive regulation of hexokinase type III activity|positive regulation of hexokinase type I activity|up-regulation of ATP-dependent hexokinase activity|up-regulation of hexokinase type IV glucokinase activity|up regulation of hexokinase activity|up regulation of hexokinase type III activity|up regulation of hexokinase type I activity|up regulation of hexokinase type IV (glucokinase) activity|up regulation of hexokinase type II activity|positive regulation of hexokinase type IV|upregulation of glucose ATP phosphotransferase activity|activation of hexokinase activity|positive regulation of hexokinase type IV (glucokinase) activity|positive regulation of hexokinase type II activity|positive regulation of hexokinase (phosphorylating)|up regulation of hexokinase type IV|up-regulation of ATP:D-hexose 6-phosphotransferase activity|up regulation of hexokinase (phosphorylating)|up-regulation of hexokinase D|activation of ATP:D-hexose 6-phosphotransferase activity|activation of hexokinase type IV (glucokinase) activity|upregulation of ATP-dependent hexokinase activity http://purl.obolibrary.org/obo/GO_1903301 GO:1903300 biolink:BiologicalProcess negative regulation of hexokinase activity Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity. go-plus.json down regulation of ATP-dependent hexokinase activity|down regulation of hexokinase type IV|down regulation of hexokinase type IV glucokinase activity|down-regulation of ATP:D-hexose 6-phosphotransferase activity|negative regulation of ATP:D-hexose 6-phosphotransferase activity|down regulation of hexokinase (phosphorylating)|down-regulation of hexokinase D|negative regulation of hexokinase D|inhibition of hexokinase activity|inhibition of hexokinase (phosphorylating)|downregulation of ATP-dependent hexokinase activity|inhibition of hexokinase type I activity|inhibition of hexokinase type III activity|downregulation of hexokinase type IV glucokinase activity|negative regulation of glucose ATP phosphotransferase activity|inhibition of hexokinase type IV|down-regulation of glucose ATP phosphotransferase activity|inhibition of hexokinase type IV (glucokinase) activity|inhibition of hexokinase type II activity|downregulation of ATP:D-hexose 6-phosphotransferase activity|downregulation of hexokinase D|down-regulation of ATP-dependent hexokinase activity|negative regulation of ATP-dependent hexokinase activity|negative regulation of hexokinase type IV glucokinase activity|inhibition of glucose ATP phosphotransferase activity|down regulation of ATP:D-hexose 6-phosphotransferase activity|down-regulation of hexokinase type IV glucokinase activity|down regulation of hexokinase type IV (glucokinase) activity|down regulation of hexokinase D|down regulation of hexokinase activity|negative regulation of hexokinase type I activity|down-regulation of hexokinase type I activity|negative regulation of hexokinase type III activity|inhibition of ATP:D-hexose 6-phosphotransferase activity|down-regulation of hexokinase type III activity|down regulation of hexokinase type II activity|downregulation of hexokinase type IV (glucokinase) activity|negative regulation of hexokinase type IV|downregulation of hexokinase activity|down-regulation of hexokinase type IV|downregulation of hexokinase type II activity|inhibition of ATP-dependent hexokinase activity|inhibition of hexokinase type IV glucokinase activity|down-regulation of hexokinase (phosphorylating)|negative regulation of hexokinase (phosphorylating)|inhibition of hexokinase D|downregulation of hexokinase type I activity|downregulation of hexokinase type III activity|down regulation of glucose ATP phosphotransferase activity|down-regulation of hexokinase activity|negative regulation of hexokinase type IV (glucokinase) activity|downregulation of hexokinase type IV|down-regulation of hexokinase type IV (glucokinase) activity|negative regulation of hexokinase type II activity|down regulation of hexokinase type III activity|down regulation of hexokinase type I activity|down-regulation of hexokinase type II activity|downregulation of hexokinase (phosphorylating)|downregulation of glucose ATP phosphotransferase activity http://purl.obolibrary.org/obo/GO_1903300 CHEBI:133653 biolink:ChemicalSubstance hydroperoxy(hydroxy)icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133653 CHEBI:133652 biolink:ChemicalSubstance hydroperoxy(epoxy)icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133652 CHEBI:133654 biolink:ChemicalSubstance hydroxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133654 CHEBI:157625 biolink:ChemicalSubstance alpha-D-mannopyranuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_157625 chebi_ph7_3 GO:1903319 biolink:BiologicalProcess positive regulation of protein maturation Any process that activates or increases the frequency, rate or extent of protein maturation. go-plus.json upregulation of protein maturation|up-regulation of protein maturation|activation of protein maturation|up regulation of protein maturation http://purl.obolibrary.org/obo/GO_1903319 GO:1903318 biolink:BiologicalProcess negative regulation of protein maturation Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation. go-plus.json down regulation of protein maturation|inhibition of protein maturation|down-regulation of protein maturation|downregulation of protein maturation http://purl.obolibrary.org/obo/GO_1903318 GO:1903317 biolink:BiologicalProcess regulation of protein maturation Any process that modulates the frequency, rate or extent of protein maturation. go-plus.json http://purl.obolibrary.org/obo/GO_1903317 GO:1903316 biolink:BiologicalProcess positive regulation of nitrogen cycle metabolic process Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process. go-plus.json up-regulation of nitrogen cycle metabolic process|activation of nitrogen cycle metabolic process|up regulation of nitrogen cycle metabolic process|upregulation of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_1903316 GO:1903315 biolink:BiologicalProcess negative regulation of nitrogen cycle metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process. go-plus.json down-regulation of nitrogen cycle metabolic process|downregulation of nitrogen cycle metabolic process|down regulation of nitrogen cycle metabolic process|inhibition of nitrogen cycle metabolic process http://purl.obolibrary.org/obo/GO_1903315 GO:1903314 biolink:BiologicalProcess regulation of nitrogen cycle metabolic process Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1903314 GO:1903313 biolink:BiologicalProcess positive regulation of mRNA metabolic process Any process that activates or increases the frequency, rate or extent of mRNA metabolic process. go-plus.json upregulation of mRNA metabolism|up-regulation of mRNA metabolic process|activation of mRNA metabolic process|up regulation of mRNA metabolism|positive regulation of mRNA metabolism|activation of mRNA metabolism|up regulation of mRNA metabolic process|up-regulation of mRNA metabolism|upregulation of mRNA metabolic process http://purl.obolibrary.org/obo/GO_1903313 CHEBI:167047 biolink:ChemicalSubstance mannosyl-alpha-1->6-inositol-1-phosphodihydroceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_167047 GO:1903312 biolink:BiologicalProcess negative regulation of mRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process. go-plus.json down regulation of mRNA metabolism|downregulation of mRNA metabolism|down-regulation of mRNA metabolic process|down-regulation of mRNA metabolism|negative regulation of mRNA metabolism|downregulation of mRNA metabolic process|down regulation of mRNA metabolic process|inhibition of mRNA metabolism|inhibition of mRNA metabolic process http://purl.obolibrary.org/obo/GO_1903312 GO:1903311 biolink:BiologicalProcess regulation of mRNA metabolic process Any process that modulates the frequency, rate or extent of mRNA metabolic process. go-plus.json regulation of mRNA metabolism http://purl.obolibrary.org/obo/GO_1903311 GO:1903310 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903310 GO:1903320 biolink:BiologicalProcess regulation of protein modification by small protein conjugation or removal Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal. go-plus.json http://purl.obolibrary.org/obo/GO_1903320 CHEBI:133661 biolink:ChemicalSubstance hyocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133661 chebi_ph7_3 CHEBI:167056 biolink:ChemicalSubstance polyprenol diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_167056 CHEBI:167055 biolink:ChemicalSubstance Jasmonate derivatives go-plus.json http://purl.obolibrary.org/obo/CHEBI_167055 CHEBI:157606 biolink:ChemicalSubstance sphinga-(4E,8Z)-dienine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_157606 chebi_ph7_3 GO:1903329 biolink:BiologicalProcess regulation of iron-sulfur cluster assembly Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1903329 GO:1903328 biolink:BiologicalProcess positive regulation of tRNA metabolic process Any process that activates or increases the frequency, rate or extent of tRNA metabolic process. go-plus.json up-regulation of tRNA metabolism|up regulation of tRNA metabolic process|upregulation of tRNA metabolism|upregulation of tRNA metabolic process|up regulation of tRNA metabolism|activation of tRNA metabolism|positive regulation of tRNA metabolism|up-regulation of tRNA metabolic process|activation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903328 GO:1903327 biolink:BiologicalProcess negative regulation of tRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process. go-plus.json inhibition of tRNA metabolism|down-regulation of tRNA metabolic process|downregulation of tRNA metabolic process|down regulation of tRNA metabolism|down regulation of tRNA metabolic process|inhibition of tRNA metabolic process|downregulation of tRNA metabolism|down-regulation of tRNA metabolism|negative regulation of tRNA metabolism http://purl.obolibrary.org/obo/GO_1903327 GO:1903326 biolink:BiologicalProcess regulation of tRNA metabolic process Any process that modulates the frequency, rate or extent of tRNA metabolic process. go-plus.json regulation of tRNA metabolism http://purl.obolibrary.org/obo/GO_1903326 GO:1903325 biolink:BiologicalProcess positive regulation of snoRNA metabolic process Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process. go-plus.json up-regulation of snoRNA metabolism|up regulation of snoRNA metabolic process|upregulation of snoRNA metabolism|upregulation of snoRNA metabolic process|up regulation of snoRNA metabolism|activation of snoRNA metabolism|positive regulation of snoRNA metabolism|up-regulation of snoRNA metabolic process|activation of snoRNA metabolic process http://purl.obolibrary.org/obo/GO_1903325 GO:1903324 biolink:BiologicalProcess negative regulation of snoRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process. go-plus.json inhibition of snoRNA metabolism|down-regulation of snoRNA metabolic process|downregulation of snoRNA metabolic process|down regulation of snoRNA metabolism|down regulation of snoRNA metabolic process|downregulation of snoRNA metabolism|inhibition of snoRNA metabolic process|negative regulation of snoRNA metabolism|down-regulation of snoRNA metabolism http://purl.obolibrary.org/obo/GO_1903324 GO:1903323 biolink:BiologicalProcess regulation of snoRNA metabolic process Any process that modulates the frequency, rate or extent of snoRNA metabolic process. go-plus.json regulation of snoRNA metabolism http://purl.obolibrary.org/obo/GO_1903323 CHEBI:167057 biolink:ChemicalSubstance Monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_167057 GO:1903322 biolink:BiologicalProcess positive regulation of protein modification by small protein conjugation or removal Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal. go-plus.json up-regulation of protein modification by small protein conjugation or removal|activation of protein modification by small protein conjugation or removal|up regulation of protein modification by small protein conjugation or removal|upregulation of protein modification by small protein conjugation or removal http://purl.obolibrary.org/obo/GO_1903322 GO:1903321 biolink:BiologicalProcess negative regulation of protein modification by small protein conjugation or removal Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal. go-plus.json down-regulation of protein modification by small protein conjugation or removal|downregulation of protein modification by small protein conjugation or removal|down regulation of protein modification by small protein conjugation or removal|inhibition of protein modification by small protein conjugation or removal http://purl.obolibrary.org/obo/GO_1903321 GO:1903331 biolink:BiologicalProcess positive regulation of iron-sulfur cluster assembly Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly. go-plus.json upregulation of iron-sulfur cluster biosynthesis|upregulation of iron-sulfur cluster assembly|up regulation of iron-sulphur cluster assembly|activation of iron-sulphur cluster assembly|positive regulation of iron-sulphur cluster assembly|up-regulation of iron-sulfur cluster biosynthesis|up-regulation of iron-sulfur cluster assembly|activation of iron-sulfur cluster assembly|activation of iron-sulfur cluster biosynthesis|up-regulation of iron-sulphur cluster assembly|positive regulation of iron-sulfur cluster biosynthesis|up regulation of iron-sulfur cluster biosynthesis|up regulation of iron-sulfur cluster assembly|upregulation of iron-sulphur cluster assembly http://purl.obolibrary.org/obo/GO_1903331 GO:1903330 biolink:BiologicalProcess negative regulation of iron-sulfur cluster assembly Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly. go-plus.json down regulation of iron-sulphur cluster assembly|down regulation of iron-sulfur cluster biosynthesis|down regulation of iron-sulfur cluster assembly|inhibition of iron-sulfur cluster assembly|downregulation of iron-sulphur cluster assembly|inhibition of iron-sulfur cluster biosynthesis|down-regulation of iron-sulphur cluster assembly|negative regulation of iron-sulphur cluster assembly|inhibition of iron-sulphur cluster assembly|down-regulation of iron-sulfur cluster biosynthesis|negative regulation of iron-sulfur cluster biosynthesis|down-regulation of iron-sulfur cluster assembly|downregulation of iron-sulfur cluster biosynthesis|downregulation of iron-sulfur cluster assembly http://purl.obolibrary.org/obo/GO_1903330 CHEBI:133631 biolink:ChemicalSubstance 1-palmitoyl-2-icosatrienoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133631 chebi_ph7_3 GO:1903339 biolink:BiologicalProcess negative regulation of cell wall organization or biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis. go-plus.json down-regulation of cell wall organization or biogenesis|downregulation of cell wall organisation or biogenesis|negative regulation of cell wall organization or biogenesis at cellular level|inhibition of cellular cell wall organisation or biogenesis|down-regulation of cell wall organization or biogenesis at cellular level|negative regulation of cellular cell wall organization or biogenesis|down-regulation of cellular cell wall organization or biogenesis|down regulation of cell wall organisation or biogenesis|inhibition of cell wall organisation or biogenesis|downregulation of cell wall organization or biogenesis|inhibition of cellular cell wall organization or biogenesis|down regulation of cell wall organization or biogenesis|inhibition of cell wall organization or biogenesis|downregulation of cell wall organization or biogenesis at cellular level|down regulation of cellular cell wall organisation or biogenesis|down regulation of cell wall organization or biogenesis at cellular level|inhibition of cell wall organization or biogenesis at cellular level|downregulation of cellular cell wall organisation or biogenesis|negative regulation of cell wall organisation or biogenesis|down regulation of cellular cell wall organization or biogenesis|down-regulation of cell wall organisation or biogenesis|downregulation of cellular cell wall organization or biogenesis|down-regulation of cellular cell wall organisation or biogenesis|negative regulation of cellular cell wall organisation or biogenesis http://purl.obolibrary.org/obo/GO_1903339 GO:1903338 biolink:BiologicalProcess regulation of cell wall organization or biogenesis Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis. go-plus.json regulation of cell wall organisation or biogenesis|regulation of cell wall organization or biogenesis at cellular level|regulation of cellular cell wall organisation or biogenesis|regulation of cellular cell wall organization or biogenesis http://purl.obolibrary.org/obo/GO_1903338 GO:1903337 biolink:BiologicalProcess positive regulation of vacuolar transport Any process that activates or increases the frequency, rate or extent of vacuolar transport. go-plus.json upregulation of vacuolar transport|up-regulation of vacuolar transport|activation of vacuolar transport|up regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903337 GO:1903336 biolink:BiologicalProcess negative regulation of vacuolar transport Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. go-plus.json inhibition of vacuolar transport|down-regulation of vacuolar transport|downregulation of vacuolar transport|down regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903336 GO:1903335 biolink:BiologicalProcess regulation of vacuolar transport Any process that modulates the frequency, rate or extent of vacuolar transport. go-plus.json http://purl.obolibrary.org/obo/GO_1903335 GO:1903334 biolink:BiologicalProcess positive regulation of protein folding Any process that activates or increases the frequency, rate or extent of protein folding. go-plus.json positive regulation of glycoprotein-specific chaperone activity|activation of co-chaperonin activity|up regulation of chaperonin-mediated tubulin folding|up regulation of glycoprotein-specific chaperone activity|up-regulation of co-chaperone activity|positive regulation of chaperonin-mediated tubulin folding|positive regulation of beta-tubulin folding|positive regulation of chaperone activity|up regulation of beta-tubulin folding|positive regulation of co-chaperonin activity|up-regulation of chaperonin ATPase activity|up-regulation of protein folding|up regulation of chaperone activity|up-regulation of protein complex assembly, multichaperone pathway|upregulation of non-chaperonin molecular chaperone ATPase activity|up regulation of alpha-tubulin folding|up regulation of co-chaperonin activity|activation of chaperonin-mediated tubulin folding|positive regulation of alpha-tubulin folding|upregulation of co-chaperone activity|activation of chaperonin ATPase activity|upregulation of glycoprotein-specific chaperone activity|activation of protein complex assembly, multichaperone pathway|upregulation of protein folding|activation of alpha-tubulin folding|up-regulation of chaperonin-mediated tubulin folding|upregulation of beta-tubulin folding|up-regulation of non-chaperonin molecular chaperone ATPase activity|positive regulation of chaperonin ATPase activity|upregulation of chaperone activity|upregulation of co-chaperonin activity|positive regulation of protein complex assembly, multichaperone pathway|up regulation of chaperonin ATPase activity|up regulation of protein complex assembly, multichaperone pathway|up-regulation of alpha-tubulin folding|up-regulation of glycoprotein-specific chaperone activity|up regulation of co-chaperone activity|activation of non-chaperonin molecular chaperone ATPase activity|upregulation of chaperonin-mediated tubulin folding|positive regulation of co-chaperone activity|up-regulation of beta-tubulin folding|up regulation of protein folding|up-regulation of chaperone activity|activation of protein folding|up-regulation of co-chaperonin activity|positive regulation of non-chaperonin molecular chaperone ATPase activity|activation of glycoprotein-specific chaperone activity|upregulation of chaperonin ATPase activity|activation of co-chaperone activity|upregulation of protein complex assembly, multichaperone pathway|upregulation of alpha-tubulin folding|up regulation of non-chaperonin molecular chaperone ATPase activity|activation of beta-tubulin folding|activation of chaperone activity http://purl.obolibrary.org/obo/GO_1903334 GO:1903333 biolink:BiologicalProcess negative regulation of protein folding Any process that stops, prevents or reduces the frequency, rate or extent of protein folding. go-plus.json downregulation of non-chaperonin molecular chaperone ATPase activity|negative regulation of chaperone activity|down regulation of alpha-tubulin folding|down-regulation of chaperone activity|inhibition of chaperonin ATPase activity|negative regulation of co-chaperonin activity|inhibition of protein complex assembly, multichaperone pathway|down-regulation of co-chaperonin activity|inhibition of protein folding|down regulation of non-chaperonin molecular chaperone ATPase activity|downregulation of alpha-tubulin folding|downregulation of glycoprotein-specific chaperone activity|inhibition of co-chaperone activity|down-regulation of chaperonin-mediated tubulin folding|negative regulation of chaperonin-mediated tubulin folding|downregulation of beta-tubulin folding|down regulation of glycoprotein-specific chaperone activity|downregulation of chaperone activity|downregulation of co-chaperonin activity|inhibition of non-chaperonin molecular chaperone ATPase activity|negative regulation of chaperonin ATPase activity|down-regulation of chaperonin ATPase activity|down regulation of beta-tubulin folding|negative regulation of alpha-tubulin folding|down-regulation of protein complex assembly, multichaperone pathway|down-regulation of alpha-tubulin folding|down regulation of chaperone activity|negative regulation of protein complex assembly, multichaperone pathway|down regulation of co-chaperonin activity|down regulation of co-chaperone activity|down regulation of protein folding|inhibition of glycoprotein-specific chaperone activity|downregulation of co-chaperone activity|inhibition of chaperonin-mediated tubulin folding|inhibition of beta-tubulin folding|downregulation of protein folding|inhibition of chaperone activity|downregulation of chaperonin ATPase activity|inhibition of co-chaperonin activity|downregulation of protein complex assembly, multichaperone pathway|negative regulation of non-chaperonin molecular chaperone ATPase activity|down-regulation of non-chaperonin molecular chaperone ATPase activity|down regulation of chaperonin ATPase activity|inhibition of alpha-tubulin folding|down regulation of chaperonin-mediated tubulin folding|down regulation of protein complex assembly, multichaperone pathway|down-regulation of co-chaperone activity|negative regulation of co-chaperone activity|down-regulation of glycoprotein-specific chaperone activity|negative regulation of glycoprotein-specific chaperone activity|down-regulation of protein folding|downregulation of chaperonin-mediated tubulin folding|down-regulation of beta-tubulin folding|negative regulation of beta-tubulin folding http://purl.obolibrary.org/obo/GO_1903333 GO:1903332 biolink:BiologicalProcess regulation of protein folding Any process that modulates the frequency, rate or extent of protein folding. go-plus.json regulation of alpha-tubulin folding|regulation of non-chaperonin molecular chaperone ATPase activity|regulation of glycoprotein-specific chaperone activity|regulation of beta-tubulin folding|regulation of chaperone activity|regulation of co-chaperonin activity|regulation of co-chaperone activity|regulation of chaperonin ATPase activity|regulation of protein complex assembly, multichaperone pathway|regulation of chaperonin-mediated tubulin folding http://purl.obolibrary.org/obo/GO_1903332 GO:1903342 biolink:BiologicalProcess negative regulation of meiotic DNA double-strand break formation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation. go-plus.json down regulation of meiotic DNA double-strand break formation|downregulation of meiotic DNA double-strand break formation|down-regulation of meiotic DNA double-strand break formation|inhibition of meiotic DNA double-strand break formation http://purl.obolibrary.org/obo/GO_1903342 GO:1903341 biolink:BiologicalProcess regulation of meiotic DNA double-strand break formation Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation. go-plus.json http://purl.obolibrary.org/obo/GO_1903341 GO:1903340 biolink:BiologicalProcess positive regulation of cell wall organization or biogenesis Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis. go-plus.json upregulation of cellular cell wall organization or biogenesis|up-regulation of cell wall organization or biogenesis|up regulation of cellular cell wall organisation or biogenesis|activation of cell wall organization or biogenesis|activation of cellular cell wall organisation or biogenesis|positive regulation of cellular cell wall organisation or biogenesis|positive regulation of cell wall organisation or biogenesis|up-regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organization or biogenesis at cellular level|up regulation of cell wall organisation or biogenesis|up regulation of cellular cell wall organization or biogenesis|activation of cellular cell wall organization or biogenesis|positive regulation of cellular cell wall organization or biogenesis|up regulation of cell wall organization or biogenesis|up-regulation of cellular cell wall organisation or biogenesis|positive regulation of cell wall organization or biogenesis at cellular level|upregulation of cell wall organisation or biogenesis|up regulation of cell wall organization or biogenesis at cellular level|up-regulation of cellular cell wall organization or biogenesis|upregulation of cellular cell wall organisation or biogenesis|upregulation of cell wall organization or biogenesis|activation of cell wall organisation or biogenesis|up-regulation of cell wall organisation or biogenesis|upregulation of cell wall organization or biogenesis at cellular level http://purl.obolibrary.org/obo/GO_1903340 NCBITaxon:1445966 biolink:OrganismalEntity Gnetidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1445966 CHEBI:87420 biolink:ChemicalSubstance lipid A 4'-(2-aminoethyl diphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87420 CHEBI:63455 biolink:ChemicalSubstance tetronic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63455 CHEBI:63454 biolink:ChemicalSubstance pentonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63454 CHEBI:87424 biolink:ChemicalSubstance lipid A 1,4'-bis(2-aminoethyl diphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87424 CHEBI:63459 biolink:ChemicalSubstance shionone go-plus.json http://purl.obolibrary.org/obo/CHEBI_63459 chebi_ph7_3 CHEBI:87425 biolink:ChemicalSubstance juvenile hormone I acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87425 CHEBI:63458 biolink:ChemicalSubstance 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63458 chebi_ph7_3 CHEBI:143098 biolink:ChemicalSubstance Gp[2'-5']Ap[3'](3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143098 chebi_ph7_3 CHEBI:143097 biolink:ChemicalSubstance Gp[2'-5']Ap[3'] go-plus.json http://purl.obolibrary.org/obo/CHEBI_143097 CHEBI:143095 biolink:ChemicalSubstance 10-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_143095 CHEBI:143093 biolink:ChemicalSubstance 2'-3'-cGAMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143093 chebi_ph7_3 CHEBI:143092 biolink:ChemicalSubstance 1-palmitoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143092 chebi_ph7_3 CHEBI:63462 biolink:ChemicalSubstance glutinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63462 chebi_ph7_3 CHEBI:63461 biolink:ChemicalSubstance achilleol B go-plus.json http://purl.obolibrary.org/obo/CHEBI_63461 chebi_ph7_3 CHEBI:63460 biolink:ChemicalSubstance parkeol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63460 chebi_ph7_3 CHEBI:63466 biolink:ChemicalSubstance beta-seco-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63466 chebi_ph7_3 CHEBI:63465 biolink:ChemicalSubstance marneral go-plus.json http://purl.obolibrary.org/obo/CHEBI_63465 chebi_ph7_3 CHEBI:87410 biolink:ChemicalSubstance N-docosanoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87410 chebi_ph7_3 CHEBI:63464 biolink:ChemicalSubstance alpha-seco-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63464 chebi_ph7_3 CHEBI:63463 biolink:ChemicalSubstance baccharis oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_63463 chebi_ph7_3 CHEBI:87415 biolink:ChemicalSubstance 7-O-[(2-aminoethyl)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87415 CHEBI:63469 biolink:ChemicalSubstance 3-hydroxy-3-phenylpropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63469 chebi_ph7_3 CHEBI:87414 biolink:ChemicalSubstance N-hexacosanoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87414 chebi_ph7_3 CHEBI:63468 biolink:ChemicalSubstance tirucalla-7,24-dien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63468 chebi_ph7_3 CHEBI:63467 biolink:ChemicalSubstance delta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63467 chebi_ph7_3 CHEBI:143087 biolink:ChemicalSubstance 1-stearoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143087 chebi_ph7_3 CHEBI:143084 biolink:ChemicalSubstance organometalloidal compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_143084 CHEBI:143081 biolink:ChemicalSubstance D-homoserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143081 chebi_ph7_3 CHEBI:143080 biolink:ChemicalSubstance D-norleucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143080 chebi_ph7_3 CHEBI:63473 biolink:ChemicalSubstance aromatic amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63473 CHEBI:63471 biolink:ChemicalSubstance branched-chain amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63471 CHEBI:63470 biolink:ChemicalSubstance sulfur-containing amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63470 CHEBI:63477 biolink:ChemicalSubstance iodothyroninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63477 CHEBI:63476 biolink:ChemicalSubstance 4-carboxylato-4'-sulfonatoazobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63476 chebi_ph7_3 CHEBI:143089 biolink:ChemicalSubstance 10-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_143089 chebi_ph7_3 CHEBI:63475 biolink:ChemicalSubstance ectoinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63475 CHEBI:63474 biolink:ChemicalSubstance arsonoacetic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63474 CHEBI:87447 biolink:ChemicalSubstance 5-epi-valiolone 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87447 CHEBI:87449 biolink:ChemicalSubstance trans-caffeoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87449 CHEBI:63488 biolink:ChemicalSubstance beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_63488 chebi_ph7_3 CHEBI:87433 biolink:ChemicalSubstance (R)-2-hydroxy-4-methylpentanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87433 CHEBI:143079 biolink:ChemicalSubstance D-leucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143079 chebi_ph7_3 CHEBI:87435 biolink:ChemicalSubstance 11-cis-retinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87435 chebi_ph7_3 CHEBI:87436 biolink:ChemicalSubstance 4-methylpent-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87436 CHEBI:87438 biolink:ChemicalSubstance lithocholyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87438 chebi_ph7_3 CHEBI:63490 biolink:ChemicalSubstance explosive go-plus.json http://purl.obolibrary.org/obo/CHEBI_63490 CHEBI:87460 biolink:ChemicalSubstance 6-hydroxy-N-methylmyosmine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87460 CHEBI:87467 biolink:ChemicalSubstance prenyl-FMNH2(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87467 chebi_ph7_3 CL:1001225 biolink:Cell kidney collecting duct cell go-plus.json http://purl.obolibrary.org/obo/CL_1001225 PR:000001221 biolink:Protein endothelin-1 receptor An endothelin receptor that is a translation product of the human EDNRA gene or a 1:1 ortholog thereof. The active form binds endothelin 1 (ET-1) and ET-2 with much higher affinity than ET-3. go-plus.json ETA-R|Gpcr10|ET-AR|ETA|endothelin receptor A|endothelin A receptor|EDNRA|ETRA|ET-A http://purl.obolibrary.org/obo/PR_000001221 PR:000001223 biolink:Protein gastrin-releasing peptide receptor A bombesin receptor that is a translation product of the human GRPR gene or a 1:1 ortholog thereof. The preferred ligand is gastrin releasing peptide. go-plus.json GRP-preferring bombesin receptor|GRPR|GRP-R http://purl.obolibrary.org/obo/PR_000001223 PR:000001225 biolink:Protein growth hormone secretagogue receptor A growth hormone secretagogue/motilin receptor that is a translation product of the human GHSR gene or a 1:1 ortholog thereof. Although its preferred ligand is ghrelin, it also binds other growth hormone releasing peptides and some nonpeptide ligands. go-plus.json GHS-R|GH-releasing peptide receptor|GHSR|GHRP|ghrelin receptor http://purl.obolibrary.org/obo/PR_000001225 CHEBI:87451 biolink:ChemicalSubstance dihydrocaffeoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87451 CHEBI:157698 biolink:ChemicalSubstance glucohexaose go-plus.json http://purl.obolibrary.org/obo/CHEBI_157698 CHEBI:87488 biolink:ChemicalSubstance short-chain 2,3-trans-enoyl CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87488 chebi_ph7_3 CHEBI:87487 biolink:ChemicalSubstance short-chain 3-substituted propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87487 chebi_ph7_3 PR:000001203 biolink:Protein C-C chemokine receptor type 7 A chemokine receptor that is a translation product of the human CCR7 gene or a 1:1 ortholog thereof. The preferred ligands are CCL19 and CCL21. go-plus.json CCR-7|CDw197|EVI1|EBV-induced G-protein coupled receptor 1|CD197|C-C CKR-7|BLR2|CC-CKR-7|MIP-3 beta receptor|EBI1|CCR7|epstein-Barr virus-induced G-protein coupled receptor 1|CMKBR7|chemokine receptor CCR7|Ebi1h http://purl.obolibrary.org/obo/PR_000001203 PR:000001202 biolink:Protein C-C chemokine receptor type 6 A chemokine receptor that is a translation product of the human CCR6 gene or a 1:1 ortholog thereof. The preferred ligand is CCL20. go-plus.json CCR-6|GPR-CY4|LARC receptor|STRL22|GPRCY4|chemokine receptor-like 3|CD196|C-C CKR-6|G-protein coupled receptor 29|CKRL3|DRY6|GPR29|CKR-L3|CC-CKR-6|KY411|CCR6|CMKBR6|chemokine receptor CCR6 http://purl.obolibrary.org/obo/PR_000001202 PR:000001206 biolink:Protein CX3C chemokine receptor 1 A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1. go-plus.json V28|fractalkine receptor|CMK-BRL-1|CMKBRL1|C-X3-C CKR-1|G-protein coupled receptor 13|GPR13|CX3CR1|CMK-BRL1|beta chemokine receptor-like 1|chemokine receptor CX3CR1 http://purl.obolibrary.org/obo/PR_000001206 PR:000001208 biolink:Protein C-X-C chemokine receptor type 4 A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12. go-plus.json pre-B-cell-derived chemokine receptor|Cmkar4|FB22|LESTR|leukocyte-derived seven transmembrane domain receptor|LCR1|chemokine receptor CXCR4|stromal cell-derived factor 1 receptor|Sdf1r|NPYRL|CXCR4|PB-CKR|CD184|CXCR-4|fusin|HM89|SDF-1 receptor|CXC-R4 http://purl.obolibrary.org/obo/PR_000001208 CHEBI:157685 biolink:ChemicalSubstance primary alkyl sulfate ester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_157685 chebi_ph7_3 CHEBI:87475 biolink:ChemicalSubstance (R)-2-hydroxybutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87475 CHEBI:87474 biolink:ChemicalSubstance (R)-2-hydroxybutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87474 chebi_ph7_3 CHEBI:87476 biolink:ChemicalSubstance (25R)-7alpha,26-dihydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87476 chebi_ph7_3 PR:000001212 biolink:Protein chemokine XC receptor 1 A chemokine receptor that is a translation product of the human XCR1 gene or a 1:1 ortholog thereof. The preferred ligands are XCL1 and XCL2. go-plus.json SCM1 receptor|GPR5|CCXCR1|chemokine receptor XCR1|lymphotactin receptor|G-protein coupled receptor 5|XC chemokine receptor 1|XCR1 http://purl.obolibrary.org/obo/PR_000001212 GO:0097079 biolink:MolecularActivity selenite:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in). go-plus.json selenite:hydrogen symporter activity|selenite:H+ symporter activity http://purl.obolibrary.org/obo/GO_0097079 GO:0097078 biolink:CellularComponent FAL1-SGD1 complex A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0097078 GO:0097075 biolink:CellularComponent interferon regulatory factor 3-interferon regulatory factor 7 complex An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7. go-plus.json IRF3:IRF7 complex http://purl.obolibrary.org/obo/GO_0097075 GO:0097074 biolink:CellularComponent interferon regulatory factor 7 complex An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7. go-plus.json IRF7:IRF7 complex http://purl.obolibrary.org/obo/GO_0097074 GO:0097077 biolink:MolecularActivity copper ion sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+). go-plus.json http://purl.obolibrary.org/obo/GO_0097077 GO:0097076 biolink:CellularComponent transforming growth factor beta activated kinase 1 complex A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits). go-plus.json TAK1 kinase complex http://purl.obolibrary.org/obo/GO_0097076 GO:0097071 biolink:CellularComponent interferon regulatory factor complex A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. go-plus.json IRF complex http://purl.obolibrary.org/obo/GO_0097071 GO:0097070 biolink:BiologicalProcess ductus arteriosus closure The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs. go-plus.json http://purl.obolibrary.org/obo/GO_0097070 GO:0097073 biolink:CellularComponent interferon regulatory factor 5 complex An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5. go-plus.json IRF5:IRF5 complex http://purl.obolibrary.org/obo/GO_0097073 CHEBI:38409 biolink:ChemicalSubstance 2,4-dichloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38409 GO:0097072 biolink:CellularComponent interferon regulatory factor 3 complex An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3. go-plus.json IRF3:IRF3 complex http://purl.obolibrary.org/obo/GO_0097072 CHEBI:38408 biolink:ChemicalSubstance chloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38408 CHEBI:38407 biolink:ChemicalSubstance muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38407 CHEBI:14434 biolink:ChemicalSubstance imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_14434 GO:0097089 biolink:BiologicalProcess methyl-branched fatty acid metabolic process The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain. go-plus.json methyl-branched fatty acid metabolism http://purl.obolibrary.org/obo/GO_0097089 GO:0097086 biolink:BiologicalProcess amniotic stem cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone. go-plus.json http://purl.obolibrary.org/obo/GO_0097086 GO:0097085 biolink:CellularComponent interferon regulatory factor 3-interferon regulatory factor 5 complex An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5. go-plus.json IRF3:IRF5 complex http://purl.obolibrary.org/obo/GO_0097085 GO:0097088 biolink:BiologicalProcess interleukin-17F production The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-17F production http://purl.obolibrary.org/obo/GO_0097088 gocheck_do_not_annotate GO:0097087 biolink:BiologicalProcess interleukin-17A production The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-17A production|interleukin-17A biosynthetic process http://purl.obolibrary.org/obo/GO_0097087 gocheck_do_not_annotate GO:0097082 biolink:BiologicalProcess vascular associated smooth muscle cell fate specification The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. go-plus.json vascular smooth muscle cell fate specification http://purl.obolibrary.org/obo/GO_0097082 GO:0097081 biolink:BiologicalProcess vascular associated smooth muscle cell fate commitment The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. go-plus.json vascular smooth muscle cell fate commitment http://purl.obolibrary.org/obo/GO_0097081 GO:0097084 biolink:BiologicalProcess vascular associated smooth muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. go-plus.json vascular smooth muscle cell development http://purl.obolibrary.org/obo/GO_0097084 GO:0097083 biolink:BiologicalProcess vascular associated smooth muscle cell fate determination The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. go-plus.json vascular smooth muscle cell fate determination http://purl.obolibrary.org/obo/GO_0097083 GO:0097080 biolink:BiologicalProcess plasma membrane selenite transport The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane. go-plus.json plasma membrane hydrogenselenite transport http://purl.obolibrary.org/obo/GO_0097080 CHEBI:14428 biolink:ChemicalSubstance hyponitrous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_14428 chebi_ph7_3 CHEBI:38412 biolink:ChemicalSubstance 2,4-dichloromuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_38412 chebi_ph7_3 CHEBI:38419 biolink:ChemicalSubstance saturated organic heterobicyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_38419 CHEBI:38418 biolink:ChemicalSubstance 1,3-thiazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_38418 CHEBI:38411 biolink:ChemicalSubstance chlorocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38411 GO:0097057 biolink:CellularComponent TRAF2-GSTP1 complex A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses. go-plus.json http://purl.obolibrary.org/obo/GO_0097057 GO:0097056 biolink:BiologicalProcess selenocysteinyl-tRNA(Sec) biosynthetic process The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine. go-plus.json selenocysteinyl-tRNA(Sec) anabolism|selenocysteinyl-tRNA(Sec) biosynthesis|selenocysteinyl-tRNA(Sec) synthesis|selenocysteinyl-tRNA(Sec) formation http://purl.obolibrary.org/obo/GO_0097056 GO:0097059 biolink:CellularComponent CNTFR-CLCF1 complex A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space. go-plus.json sCNTFR-CLC complex http://purl.obolibrary.org/obo/GO_0097059 GO:0097058 biolink:CellularComponent CRLF-CLCF1 complex A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex. go-plus.json CLF-CLC complex http://purl.obolibrary.org/obo/GO_0097058 GO:0097053 biolink:BiologicalProcess L-kynurenine catabolic process The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine). go-plus.json L-kynurenine degradation|L-kynurenine breakdown|L-kynurenine catabolism http://purl.obolibrary.org/obo/GO_0097053 GO:0097052 biolink:BiologicalProcess L-kynurenine metabolic process The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine). go-plus.json L-kynurenine metabolism http://purl.obolibrary.org/obo/GO_0097052 GO:0097055 biolink:BiologicalProcess agmatine biosynthetic process The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase. go-plus.json agmatine anabolism|agmatine synthesis|agmatine formation|agmatine biosynthesis http://purl.obolibrary.org/obo/GO_0097055 GO:0097054 biolink:BiologicalProcess L-glutamate biosynthetic process The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid. go-plus.json L-glutamate anabolism|L-glutamate synthesis|L-glutamate formation|L-glutamate biosynthesis http://purl.obolibrary.org/obo/GO_0097054 UBERON:0011693 biolink:AnatomicalEntity extraembryonic portion of umbilical artery go-plus.json extraembryonic umbilical artery http://purl.obolibrary.org/obo/UBERON_0011693 GO:0097051 biolink:BiologicalProcess establishment of protein localization to endoplasmic reticulum membrane The directed movement of a protein to a specific location in the endoplasmic reticulum membrane. go-plus.json establishment of protein localisation in endoplasmic reticulum membrane|establishment of protein localization in endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0097051 GO:0097050 biolink:BiologicalProcess type B pancreatic cell apoptotic process Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin. go-plus.json type B pancreatic cell apoptosis|pancreatic B cell apoptosis|pancreatic beta cell apoptosis http://purl.obolibrary.org/obo/GO_0097050 UBERON:0011697 biolink:AnatomicalEntity right extraembryonic umbilical artery go-plus.json extraembryonic umbilical artery right http://purl.obolibrary.org/obo/UBERON_0011697 UBERON:0011696 biolink:AnatomicalEntity left extraembryonic umbilical artery go-plus.json extraembryonic umbilical artery left http://purl.obolibrary.org/obo/UBERON_0011696 UBERON:0011695 biolink:AnatomicalEntity embryonic cardiovascular system A cardiovascular system that is part of a conceptus. go-plus.json conceptus cardiovascular system|embryonic circulatory system|fetal circulatory system http://purl.obolibrary.org/obo/UBERON_0011695 CL:1001320 biolink:Cell urethra cell go-plus.json http://purl.obolibrary.org/obo/CL_1001320 GO:0097068 biolink:BiologicalProcess response to thyroxine A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus. go-plus.json response to T4|response to T4 stimulus|response to thyroxine stimulus http://purl.obolibrary.org/obo/GO_0097068 GO:0097067 biolink:BiologicalProcess cellular response to thyroid hormone stimulus A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097067 GO:0097069 biolink:BiologicalProcess cellular response to thyroxine stimulus A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus. go-plus.json cellular response to T4 stimulus http://purl.obolibrary.org/obo/GO_0097069 GO:0097064 biolink:BiologicalProcess ncRNA export from nucleus The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm. go-plus.json non-coding RNA export from nucleus http://purl.obolibrary.org/obo/GO_0097064 GO:0097063 biolink:MolecularActivity cadmium ion sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++). go-plus.json http://purl.obolibrary.org/obo/GO_0097063 GO:0097066 biolink:BiologicalProcess response to thyroid hormone A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. go-plus.json response to thyroid hormone stimulus http://purl.obolibrary.org/obo/GO_0097066 GO:0097065 biolink:BiologicalProcess anterior head development The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0097065 GO:0097060 biolink:CellularComponent synaptic membrane A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097060 goslim_synapse GO:0097062 biolink:BiologicalProcess dendritic spine maintenance The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0097062 CL:1001319 biolink:Cell bladder cell go-plus.json http://purl.obolibrary.org/obo/CL_1001319 GO:0097061 biolink:BiologicalProcess dendritic spine organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission. go-plus.json dendritic spine organisation http://purl.obolibrary.org/obo/GO_0097061 CL:1001318 biolink:Cell renal interstitial pericyte go-plus.json http://purl.obolibrary.org/obo/CL_1001318 UBERON:0011679 biolink:AnatomicalEntity proximal tarsal bone A tarsal bone that connected_to a hindlimb zeugopod skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011679 CHEBI:63403 biolink:ChemicalSubstance sedoheptulose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63403 CHEBI:63402 biolink:ChemicalSubstance ketose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63402 UBERON:0011677 biolink:AnatomicalEntity trunk vertebra A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes caudal/coccygeal vertebra, which are located posteriorly. In tetrapods this includes thoracic, lumbar and sacral vertebrae, and excludes the cervical vertebrae, which are located anteriorly. go-plus.json thoracolumbar vertebra|presacral vertebra http://purl.obolibrary.org/obo/UBERON_0011677 CHEBI:63401 biolink:ChemicalSubstance ketooctose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63401 CHEBI:63407 biolink:ChemicalSubstance ketotriose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63407 CHEBI:63405 biolink:ChemicalSubstance ketopentose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63405 CHEBI:63409 biolink:ChemicalSubstance pentose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63409 UBERON:0035642 biolink:AnatomicalEntity laryngeal nerve Any nerve that innervates the larynx. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035642 CHEBI:63410 biolink:ChemicalSubstance all-trans-retinyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_63410 chebi_ph7_3 CHEBI:63415 biolink:ChemicalSubstance glycodiaosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_63415 CHEBI:63413 biolink:ChemicalSubstance triose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63413 UBERON:0035639 biolink:AnatomicalEntity ocular adnexa The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva go-plus.json appendages of the eye|set of accessory visual structures|adnexa oculi|appendage of eye|accessory parts of orbital region|structurae oculi accessoriae|accessory visual structures set|accessory visual structures|eye adnexa|adnexal parts of orbital region http://purl.obolibrary.org/obo/UBERON_0035639 CHEBI:63417 biolink:ChemicalSubstance UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63417 chebi_ph7_3 CHEBI:63416 biolink:ChemicalSubstance 4-amino-5-ammoniomethyl-2-methylpyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63416 chebi_ph7_3 UBERON:0035650 biolink:AnatomicalEntity nerve of clitoris Any nerve that innervates the clitoris. go-plus.json clitoral nerve|clitoris nerve http://purl.obolibrary.org/obo/UBERON_0035650 UBERON:0035651 biolink:AnatomicalEntity glans go-plus.json http://purl.obolibrary.org/obo/UBERON_0035651 CHEBI:63422 biolink:ChemicalSubstance UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63422 CHEBI:63421 biolink:ChemicalSubstance beta-L-altrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63421 chebi_ph7_3 CHEBI:63420 biolink:ChemicalSubstance UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63420 CHEBI:63426 biolink:ChemicalSubstance glucosylglycerol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63426 CHEBI:63425 biolink:ChemicalSubstance galactosylglycerol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63425 UBERON:0035649 biolink:AnatomicalEntity nerve of penis Any nerve that innervates the penis. go-plus.json penile nerve|penis nerve http://purl.obolibrary.org/obo/UBERON_0035649 CHEBI:63424 biolink:ChemicalSubstance glycosyl alditol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63424 UBERON:0035648 biolink:AnatomicalEntity nerve innervating pinna Any nerve that innervates the pinna. go-plus.json auricular nerve http://purl.obolibrary.org/obo/UBERON_0035648 CHEBI:63423 biolink:ChemicalSubstance alditol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63423 CHEBI:63428 biolink:ChemicalSubstance digalactosylglycerol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63428 CHEBI:63427 biolink:ChemicalSubstance glycosylglycerol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63427 OBO:GOCHE_78295 biolink:OntologyClass substance with food component role go-plus.json http://purl.obolibrary.org/obo/GOCHE_78295 3_STAR GO:0097097 biolink:BiologicalProcess nasal suture morphogenesis The process in which the nasal suture is generated and organized. go-plus.json internasal suture morphogenesis http://purl.obolibrary.org/obo/GO_0097097 GO:0097096 biolink:BiologicalProcess facial suture morphogenesis The process in which any suture between facial bones is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0097096 GO:0097099 biolink:MolecularActivity structural constituent of albumen The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo. go-plus.json structural constituent of egg white http://purl.obolibrary.org/obo/GO_0097099 GO:0097098 biolink:MolecularActivity DNA/RNA hybrid annealing activity An activity that facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops. go-plus.json http://purl.obolibrary.org/obo/GO_0097098 GO:0097093 biolink:BiologicalProcess polyacyltrehalose biosynthetic process The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid. go-plus.json polyacyltrehalose biosynthesis|polyacyltrehalose anabolism|polyacyltrehalose synthesis|polyacyltrehalose formation http://purl.obolibrary.org/obo/GO_0097093 GO:0097092 biolink:BiologicalProcess polyacyltrehalose metabolic process The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid. go-plus.json polyacyltrehalose metabolism http://purl.obolibrary.org/obo/GO_0097092 GO:0097095 biolink:BiologicalProcess frontonasal suture morphogenesis The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized. go-plus.json nasofrontal suture morphogenesis http://purl.obolibrary.org/obo/GO_0097095 GO:0097094 biolink:BiologicalProcess craniofacial suture morphogenesis The process in which any suture between cranial and/or facial bones is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0097094 CHEBI:63432 biolink:ChemicalSubstance galactitol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63432 GO:0097091 biolink:BiologicalProcess synaptic vesicle clustering The process that results in grouping synaptic vesicles in presynaptic structures. go-plus.json http://purl.obolibrary.org/obo/GO_0097091 goslim_synapse GO:0097090 biolink:BiologicalProcess presynaptic membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction. go-plus.json presynaptic membrane organisation|pre-synaptic membrane organization http://purl.obolibrary.org/obo/GO_0097090 CHEBI:63430 biolink:ChemicalSubstance hexitol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63430 CHEBI:63437 biolink:ChemicalSubstance aldaric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63437 CHEBI:63436 biolink:ChemicalSubstance carbohydrate acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63436 CHEBI:63435 biolink:ChemicalSubstance tetritol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63435 CHEBI:63434 biolink:ChemicalSubstance pentitol derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63434 CHEBI:63438 biolink:ChemicalSubstance hexaric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63438 CHEBI:63444 biolink:ChemicalSubstance viridiflorene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63444 chebi_ph7_3 CHEBI:63443 biolink:ChemicalSubstance alpha-guaiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63443 chebi_ph7_3 CHEBI:63442 biolink:ChemicalSubstance hexonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63442 CHEBI:63441 biolink:ChemicalSubstance aldonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63441 CHEBI:63447 biolink:ChemicalSubstance delta-guaiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63447 chebi_ph7_3 CHEBI:63446 biolink:ChemicalSubstance (-)-cubebol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63446 chebi_ph7_3 CHEBI:63445 biolink:ChemicalSubstance 5-epi-alpha-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63445 chebi_ph7_3 GO:0048068 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048068 GO:0048067 biolink:BiologicalProcess cuticle pigmentation Establishment of a pattern of pigment in the cuticle of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0048067 GO:0048066 biolink:BiologicalProcess developmental pigmentation The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. go-plus.json pigmentation during development http://purl.obolibrary.org/obo/GO_0048066 GO:0048065 biolink:BiologicalProcess male courtship behavior, veined wing extension The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster. go-plus.json male courtship behaviour, veined wing extension|male courtship behavior, wing extension|male courtship behaviour, wing extension http://purl.obolibrary.org/obo/GO_0048065 GO:0048064 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048064 GO:0048063 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048063 GO:0048062 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048062 GO:0048061 biolink:BiologicalProcess positive gravitaxis The directed movement of a motile cell or organism towards the source of gravity. go-plus.json positive geotactic behavior|positive geotactic behaviour|positive taxis in response to gravity|positive taxis in response to gravitytaxis in response to gravitational stimulus|positive gravitactic behavior|positive gravitactic behaviour http://purl.obolibrary.org/obo/GO_0048061 NCBITaxon:85011 biolink:OrganismalEntity Streptomycetales go-plus.json Streptomycetes|Streptomycetineae|Streptomycineae http://purl.obolibrary.org/obo/NCBITaxon_85011 GO:1903229 biolink:BiologicalProcess xanthosine biosynthetic process The chemical reactions and pathways resulting in the formation of xanthosine. go-plus.json xanthosine anabolism|xanthosine synthesis|xanthosine formation|xanthosine biosynthesis http://purl.obolibrary.org/obo/GO_1903229 GO:0014728 biolink:BiologicalProcess regulation of the force of skeletal muscle contraction Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges. go-plus.json http://purl.obolibrary.org/obo/GO_0014728 GO:1903228 biolink:BiologicalProcess xanthosine catabolic process The chemical reactions and pathways resulting in the breakdown of xanthosine. go-plus.json xanthosine catabolism|xanthosine degradation|xanthosine breakdown http://purl.obolibrary.org/obo/GO_1903228 GO:0014727 biolink:BiologicalProcess positive regulation of extraocular skeletal muscle development Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0014727 GO:1903227 biolink:BiologicalProcess xanthosine metabolic process The chemical reactions and pathways involving xanthosine. go-plus.json xanthosine metabolism http://purl.obolibrary.org/obo/GO_1903227 GO:0014726 biolink:BiologicalProcess negative regulation of extraocular skeletal muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0014726 CHEBI:133738 biolink:ChemicalSubstance 2-hydroxyhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133738 chebi_ph7_3 GO:0014725 biolink:BiologicalProcess regulation of extraocular skeletal muscle development Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0014725 GO:1903226 biolink:BiologicalProcess positive regulation of endodermal cell differentiation Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. go-plus.json up regulation of endoderm cell differentiation|upregulation of endodermal cell differentiation|activation of endoderm cell differentiation|positive regulation of endoderm cell differentiation|up regulation of endodermal cell differentiation|activation of endodermal cell differentiation|up-regulation of endoderm cell differentiation|upregulation of endoderm cell differentiation|up-regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_1903226 GO:1903225 biolink:BiologicalProcess negative regulation of endodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. go-plus.json down regulation of endodermal cell differentiation|negative regulation of endoderm cell differentiation|down-regulation of endoderm cell differentiation|downregulation of endodermal cell differentiation|inhibition of endoderm cell differentiation|down-regulation of endodermal cell differentiation|inhibition of endodermal cell differentiation|down regulation of endoderm cell differentiation|downregulation of endoderm cell differentiation http://purl.obolibrary.org/obo/GO_1903225 GO:1903224 biolink:BiologicalProcess regulation of endodermal cell differentiation Any process that modulates the frequency, rate or extent of endodermal cell differentiation. go-plus.json regulation of endoderm cell differentiation http://purl.obolibrary.org/obo/GO_1903224 GO:1903223 biolink:BiologicalProcess positive regulation of oxidative stress-induced neuron death Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron death. go-plus.json up-regulation of neuron death in response to oxidative stress|activation of neuron death in response to oxidative stress|upregulation of neuronal cell death in response to oxidative stress|up regulation of oxidative stress-induced neuron death|activation of oxidative stress-induced neuron death|up regulation of neuronal cell death in response to oxidative stress|positive regulation of neuron death in response to oxidative stress|up regulation of neuron death in response to oxidative stress|positive regulation of neuronal cell death in response to oxidative stress|activation of neuronal cell death in response to oxidative stress|up-regulation of oxidative stress-induced neuron death|upregulation of neuron death in response to oxidative stress|upregulation of oxidative stress-induced neuron death|up-regulation of neuronal cell death in response to oxidative stress|sensitization of neuron to oxidative stress-induced cell death http://purl.obolibrary.org/obo/GO_1903223 GO:0048069 biolink:BiologicalProcess eye pigmentation Establishment of a pattern of pigment in the eye of an organism. Wikipedia:Eye_color go-plus.json http://purl.obolibrary.org/obo/GO_0048069 GO:1903222 biolink:BiologicalProcess quinolinic acid transmembrane transport The process in which quinolinic acid is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903222 GO:0014729 biolink:BiologicalProcess regulation of the velocity of shortening of skeletal muscle modulating contraction Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres. go-plus.json regulation of the velocity of shortening of skeletal muscle during contraction http://purl.obolibrary.org/obo/GO_0014729 GO:1903232 biolink:BiologicalProcess melanosome assembly The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. go-plus.json melanosome formation http://purl.obolibrary.org/obo/GO_1903232 GO:0014720 biolink:BiologicalProcess tonic skeletal muscle contraction A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue. go-plus.json http://purl.obolibrary.org/obo/GO_0014720 GO:1903231 biolink:MolecularActivity mRNA binding involved in posttranscriptional gene silencing Any mRNA binding that is involved in posttranscriptional gene silencing. go-plus.json mRNA binding involved in quelling|mRNA binding involved in post-transcriptional gene silencing|mRNA binding involved in cosuppression|mRNA binding involved in PTGS http://purl.obolibrary.org/obo/GO_1903231 GO:1903230 biolink:MolecularActivity obsolete miRNA binding involved in posttranscriptional gene silencing OBSOLETE. Any miRNA binding that is involved in posttranscriptional gene silencing. go-plus.json microRNA binding involved in PTGS|microRNA binding involved in post-transcriptional gene silencing|microRNA binding involved in cosuppression|miRNA binding involved in PTGS|microRNA binding involved in quelling|miRNA binding involved in posttranscriptional gene silencing|miRNA binding involved in quelling|microRNA binding involved in posttranscriptional gene silencing|miRNA binding involved in post-transcriptional gene silencing|miRNA binding involved in cosuppression http://purl.obolibrary.org/obo/GO_1903230 GO:0014724 biolink:BiologicalProcess regulation of twitch skeletal muscle contraction Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014724 GO:0014723 biolink:BiologicalProcess regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril. go-plus.json regulation of calcium ion sensitivity of myofibril involved in skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0014723 UBERON:0011628 biolink:AnatomicalEntity early premaxilla go-plus.json future premaxilla http://purl.obolibrary.org/obo/UBERON_0011628 GO:0014722 biolink:BiologicalProcess regulation of skeletal muscle contraction by calcium ion signaling Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction. go-plus.json regulation of skeletal muscle contraction by calcium ion signalling http://purl.obolibrary.org/obo/GO_0014722 GO:0014721 biolink:BiologicalProcess twitch skeletal muscle contraction A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation. go-plus.json http://purl.obolibrary.org/obo/GO_0014721 CHEBI:38484 biolink:ChemicalSubstance ergoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_38484 GO:0048071 biolink:BiologicalProcess sex-specific pigmentation Establishment of a pattern of pigment in one sex that is not observed in the other sex. go-plus.json http://purl.obolibrary.org/obo/GO_0048071 GO:0048070 biolink:BiologicalProcess regulation of developmental pigmentation Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. go-plus.json regulation of pigmentation during development http://purl.obolibrary.org/obo/GO_0048070 CHEBI:38482 biolink:ChemicalSubstance indole alkaloid fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_38482 CHEBI:38481 biolink:ChemicalSubstance alkaloid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_38481 GO:0097002 biolink:CellularComponent mitochondrial inner boundary membrane The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane. NIF_Subcellular:sao18461326 go-plus.json inner bounding mitochondrial membrane http://purl.obolibrary.org/obo/GO_0097002 GO:0048079 biolink:BiologicalProcess regulation of cuticle pigmentation Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0048079 GO:0048078 biolink:BiologicalProcess positive regulation of compound eye pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye. go-plus.json upregulation of eye pigmentation|up-regulation of eye pigmentation|stimulation of eye pigmentation|activation of eye pigmentation|positive regulation of eye pigmentation|up regulation of eye pigmentation http://purl.obolibrary.org/obo/GO_0048078 GO:0097001 biolink:MolecularActivity ceramide binding Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0097001 GO:0048077 biolink:BiologicalProcess negative regulation of compound eye pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye. go-plus.json downregulation of eye pigmentation|down regulation of eye pigmentation|inhibition of eye pigmentation|down-regulation of eye pigmentation|negative regulation of eye pigmentation http://purl.obolibrary.org/obo/GO_0048077 GO:0097004 biolink:MolecularActivity adipokinetic hormone binding Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. go-plus.json AKH binding http://purl.obolibrary.org/obo/GO_0097004 GO:0048076 biolink:BiologicalProcess regulation of compound eye pigmentation Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye. go-plus.json http://purl.obolibrary.org/obo/GO_0048076 GO:0097003 biolink:MolecularActivity adipokinetic hormone receptor activity Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. go-plus.json AKH receptor activity http://purl.obolibrary.org/obo/GO_0097003 GO:0048075 biolink:BiologicalProcess positive regulation of eye pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. go-plus.json stimulation of eye pigmentation|up-regulation of eye pigmentation|activation of eye pigmentation|up regulation of eye pigmentation|upregulation of eye pigmentation http://purl.obolibrary.org/obo/GO_0048075 GO:0048074 biolink:BiologicalProcess negative regulation of eye pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. go-plus.json down-regulation of eye pigmentation|downregulation of eye pigmentation|down regulation of eye pigmentation|inhibition of eye pigmentation http://purl.obolibrary.org/obo/GO_0048074 GO:0048073 biolink:BiologicalProcess regulation of eye pigmentation Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0048073 GO:0048072 biolink:BiologicalProcess compound eye pigmentation Establishment of a pattern of pigment in the compound eye. go-plus.json http://purl.obolibrary.org/obo/GO_0048072 GO:0014739 biolink:BiologicalProcess positive regulation of muscle hyperplasia Any process that activates or increases the frequency, rate or extent of muscle hyperplasia. go-plus.json http://purl.obolibrary.org/obo/GO_0014739 GO:0014738 biolink:BiologicalProcess regulation of muscle hyperplasia Any process that modulates the frequency, rate or extent of muscle hyperplasia. go-plus.json http://purl.obolibrary.org/obo/GO_0014738 GO:1903239 biolink:BiologicalProcess obsolete regulation of positive regulation of the force of heart contraction by chemical signal OBSOLETE. Any process that modulates the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal. go-plus.json regulation of positive regulation of the force of heart muscle contraction by chemical signal|regulation of positive regulation of the force of heart contraction by chemical signal http://purl.obolibrary.org/obo/GO_1903239 GO:0014737 biolink:BiologicalProcess positive regulation of muscle atrophy Any process that activates or increases the frequency, rate or extent of muscle atrophy. go-plus.json http://purl.obolibrary.org/obo/GO_0014737 GO:1903238 biolink:BiologicalProcess positive regulation of leukocyte tethering or rolling Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling. go-plus.json up regulation of leukocyte tethering or rolling|upregulation of leukocyte tethering or rolling|activation of leukocyte tethering or rolling|up-regulation of leukocyte tethering or rolling http://purl.obolibrary.org/obo/GO_1903238 GO:1903237 biolink:BiologicalProcess negative regulation of leukocyte tethering or rolling Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling. go-plus.json down-regulation of leukocyte tethering or rolling|downregulation of leukocyte tethering or rolling|down regulation of leukocyte tethering or rolling|inhibition of leukocyte tethering or rolling http://purl.obolibrary.org/obo/GO_1903237 GO:0014736 biolink:BiologicalProcess negative regulation of muscle atrophy Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy. go-plus.json http://purl.obolibrary.org/obo/GO_0014736 CHEBI:133748 biolink:ChemicalSubstance citrate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133748 GO:1903236 biolink:BiologicalProcess regulation of leukocyte tethering or rolling Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling. go-plus.json http://purl.obolibrary.org/obo/GO_1903236 NCBITaxon:85007 biolink:OrganismalEntity Corynebacteriales go-plus.json Mycobacteriales|Corynebacterineae http://purl.obolibrary.org/obo/NCBITaxon_85007 GO:1903235 biolink:BiologicalProcess positive regulation of calcium ion-dependent exocytosis of neurotransmitter Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. go-plus.json up-regulation of calcium ion-dependent exocytosis of neurotransmitter|activation of calcium ion-dependent exocytosis of neurotransmitter|up regulation of calcium ion-dependent exocytosis of neurotransmitter|upregulation of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_1903235 GO:1903234 biolink:BiologicalProcess negative regulation of calcium ion-dependent exocytosis of neurotransmitter Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. go-plus.json down-regulation of calcium ion-dependent exocytosis of neurotransmitter|downregulation of calcium ion-dependent exocytosis of neurotransmitter|down regulation of calcium ion-dependent exocytosis of neurotransmitter|inhibition of calcium ion-dependent exocytosis of neurotransmitter http://purl.obolibrary.org/obo/GO_1903234 GO:1903233 biolink:BiologicalProcess regulation of calcium ion-dependent exocytosis of neurotransmitter Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_1903233 GO:0014731 biolink:CellularComponent spectrin-associated cytoskeleton The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0014731 GO:1903243 biolink:BiologicalProcess negative regulation of cardiac muscle hypertrophy in response to stress Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. go-plus.json downregulation of cardiac muscle hypertrophy in response to stress|down regulation of cardiac muscle hypertrophy in response to stress|inhibition of cardiac muscle hypertrophy in response to stress|down-regulation of cardiac muscle hypertrophy in response to stress http://purl.obolibrary.org/obo/GO_1903243 GO:1903242 biolink:BiologicalProcess regulation of cardiac muscle hypertrophy in response to stress Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. go-plus.json http://purl.obolibrary.org/obo/GO_1903242 GO:0014730 biolink:BiologicalProcess skeletal muscle regeneration at neuromuscular junction The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014730 GO:1903241 biolink:BiologicalProcess U2-type prespliceosome assembly The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome. go-plus.json major prespliceosome assembly|GT-AG prespliceosome formation|mammalian U2-type spliceosomal complex A assembly|yeast U2-type spliceosomal complex B formation|yeast U2-type spliceosomal complex B assembly|mammalian U2-type spliceosomal complex A formation|GT-AG prespliceosome assembly|U2-type prespliceosome formation|major prespliceosome formation http://purl.obolibrary.org/obo/GO_1903241 CHEBI:133741 biolink:ChemicalSubstance (E)-dodec-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_133741 chebi_ph7_3 GO:1903240 biolink:BiologicalProcess obsolete negative regulation of positive regulation of the force of heart contraction by chemical signal OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal. go-plus.json down-regulation of positive regulation of the force of heart contraction by chemical signal|downregulation of positive regulation of the force of heart contraction by chemical signal|down regulation of positive regulation of the force of heart muscle contraction by chemical signal|down regulation of positive regulation of the force of heart contraction by chemical signal|downregulation of positive regulation of the force of heart muscle contraction by chemical signal|inhibition of positive regulation of the force of heart contraction by chemical signal|negative regulation of positive regulation of the force of heart contraction by chemical signal|down-regulation of positive regulation of the force of heart muscle contraction by chemical signal|negative regulation of positive regulation of the force of heart muscle contraction by chemical signal|inhibition of positive regulation of the force of heart muscle contraction by chemical signal http://purl.obolibrary.org/obo/GO_1903240 GO:0014735 biolink:BiologicalProcess regulation of muscle atrophy Any process that modulates the frequency, rate or extent of muscle atrophy. go-plus.json http://purl.obolibrary.org/obo/GO_0014735 UBERON:0035606 biolink:AnatomicalEntity cartilage of external acoustic meatus go-plus.json cartilage of auditory canal|cartilago meatus acustici|external acoustic meatus cartilage|cartilage of acoustic meatus http://purl.obolibrary.org/obo/UBERON_0035606 GO:0014734 biolink:BiologicalProcess skeletal muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0014734 GO:0014733 biolink:BiologicalProcess regulation of skeletal muscle adaptation Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. go-plus.json regulation of skeletal muscle plasticity http://purl.obolibrary.org/obo/GO_0014733 UBERON:0035608 biolink:AnatomicalEntity dura mater lymph vessel Any lymph vessel that is located in the dura mater of the brain. go-plus.json dural lymph vessel|dural lymph vasculature http://purl.obolibrary.org/obo/UBERON_0035608 GO:0014732 biolink:BiologicalProcess skeletal muscle atrophy A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014732 GO:0048082 biolink:BiologicalProcess regulation of adult chitin-containing cuticle pigmentation Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0048082 GO:0048081 biolink:BiologicalProcess positive regulation of cuticle pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism. go-plus.json up regulation of cuticle pigmentation|upregulation of cuticle pigmentation|stimulation of cuticle pigmentation|up-regulation of cuticle pigmentation|activation of cuticle pigmentation http://purl.obolibrary.org/obo/GO_0048081 GO:0097009 biolink:BiologicalProcess energy homeostasis Any process involved in the balance between food intake (energy input) and energy expenditure. go-plus.json negative regulation of energy homeostasis|positive regulation of energy homeostasis|regulation of energy homeostasis http://purl.obolibrary.org/obo/GO_0097009 GO:0048080 biolink:BiologicalProcess negative regulation of cuticle pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism. go-plus.json downregulation of cuticle pigmentation|down regulation of cuticle pigmentation|inhibition of cuticle pigmentation|down-regulation of cuticle pigmentation http://purl.obolibrary.org/obo/GO_0048080 GO:0097006 biolink:BiologicalProcess regulation of plasma lipoprotein particle levels Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism. go-plus.json plasma lipoprotein particle homeostasis http://purl.obolibrary.org/obo/GO_0097006 GO:0097005 biolink:MolecularActivity adipokinetic hormone receptor binding Binding to an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. go-plus.json AKH receptor binding http://purl.obolibrary.org/obo/GO_0097005 CHEBI:38498 biolink:ChemicalSubstance mitochondrial NADH:ubiquinone reductase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38498 GO:0097008 biolink:MolecularActivity (3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone. MetaCyc:RXN-8619 go-plus.json (3E)-4,8-dimethylnona-1,3,7-triene synthase activity|DNMT synthase activity http://purl.obolibrary.org/obo/GO_0097008 CHEBI:38497 biolink:ChemicalSubstance respiratory-chain inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38497 GO:0097007 biolink:MolecularActivity 4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone. MetaCyc:RXN-8620|RHEA:13545 go-plus.json TMTT synthase activity|4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity http://purl.obolibrary.org/obo/GO_0097007 CHEBI:38496 biolink:ChemicalSubstance electron-transport chain inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38496 CHEBI:167098 biolink:ChemicalSubstance N-(fatty acyl)-ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_167098 GO:0048089 biolink:BiologicalProcess regulation of female pigmentation Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females. go-plus.json http://purl.obolibrary.org/obo/GO_0048089 CHEBI:167097 biolink:ChemicalSubstance trihexosylceramide sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_167097 GO:0048088 biolink:BiologicalProcess regulation of male pigmentation Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males. go-plus.json http://purl.obolibrary.org/obo/GO_0048088 GO:0048087 biolink:BiologicalProcess positive regulation of developmental pigmentation Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. go-plus.json up regulation of developmental pigmentation|upregulation of developmental pigmentation|stimulation of developmental pigmentation|up-regulation of developmental pigmentation|activation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048087 GO:0048086 biolink:BiologicalProcess negative regulation of developmental pigmentation Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. go-plus.json down-regulation of developmental pigmentation|downregulation of developmental pigmentation|down regulation of developmental pigmentation|inhibition of pigmentation http://purl.obolibrary.org/obo/GO_0048086 CHEBI:167094 biolink:ChemicalSubstance medium-chain 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_167094 GO:0048085 biolink:BiologicalProcess adult chitin-containing cuticle pigmentation Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster. go-plus.json adult cuticle pigmentation http://purl.obolibrary.org/obo/GO_0048085 GO:0048084 biolink:BiologicalProcess positive regulation of adult chitin-containing cuticle pigmentation Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism. go-plus.json up regulation of adult chitin-containing cuticle pigmentation|upregulation of adult chitin-containing cuticle pigmentation|stimulation of adult chitin-containing cuticle pigmentation|up-regulation of adult chitin-containing cuticle pigmentation|activation of adult chitin-containing cuticle pigmentation http://purl.obolibrary.org/obo/GO_0048084 GO:0048083 biolink:BiologicalProcess negative regulation of adult chitin-containing cuticle pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism. go-plus.json downregulation of adult chitin-containing cuticle pigmentation|down regulation of adult chitin-containing cuticle pigmentation|inhibition of adult chitin-containing cuticle pigmentation|down-regulation of adult chitin-containing cuticle pigmentation http://purl.obolibrary.org/obo/GO_0048083 CHEBI:167095 biolink:ChemicalSubstance secondary fatty alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_167095 GO:0014706 biolink:BiologicalProcess striated muscle tissue development The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. go-plus.json http://purl.obolibrary.org/obo/GO_0014706 GO:0014705 biolink:CellularComponent C zone A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin. go-plus.json http://purl.obolibrary.org/obo/GO_0014705 GO:1903249 biolink:BiologicalProcess negative regulation of citrulline biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process. go-plus.json negative regulation of citrulline biosynthesis|down-regulation of citrulline biosynthesis|down-regulation of citrulline biosynthetic process|negative regulation of citrulline formation|down-regulation of citrulline formation|downregulation of citrulline anabolism|down regulation of citrulline anabolism|downregulation of citrulline synthesis|inhibition of citrulline biosynthesis|inhibition of citrulline biosynthetic process|inhibition of citrulline anabolism|downregulation of citrulline formation|down regulation of citrulline synthesis|inhibition of citrulline synthesis|down regulation of citrulline formation|inhibition of citrulline formation|down regulation of citrulline biosynthetic process|down regulation of citrulline biosynthesis|downregulation of citrulline biosynthetic process|downregulation of citrulline biosynthesis|negative regulation of citrulline anabolism|down-regulation of citrulline anabolism|negative regulation of citrulline synthesis|down-regulation of citrulline synthesis http://purl.obolibrary.org/obo/GO_1903249 CHEBI:133716 biolink:ChemicalSubstance N-acetyl-L-valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133716 chebi_ph7_3 GO:0014704 biolink:CellularComponent intercalated disc A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells. Wikipedia:Intercalated_disc go-plus.json intercalated disk http://purl.obolibrary.org/obo/GO_0014704 GO:1903248 biolink:BiologicalProcess regulation of citrulline biosynthetic process Any process that modulates the frequency, rate or extent of citrulline biosynthetic process. go-plus.json regulation of citrulline anabolism|regulation of citrulline synthesis|regulation of citrulline formation|regulation of citrulline biosynthesis http://purl.obolibrary.org/obo/GO_1903248 GO:0014703 biolink:BiologicalProcess oscillatory muscle contraction A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation. go-plus.json http://purl.obolibrary.org/obo/GO_0014703 GO:1903247 biolink:BiologicalProcess obsolete positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate OBSOLETE. Any process that activates or increases the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate. go-plus.json activation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|upregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of activation of funny current by beta-adrenergic receptor signaling pathway|upregulation of If activation by beta-adrenergic receptor signaling pathway|up-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|positive regulation of activation of funny current by beta-adrenergic receptor signaling pathway|positive regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|positive regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of activation of funny current by beta-adrenergic receptor signaling pathway|up-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|positive regulation of If activation by beta-adrenergic receptor signaling pathway|activation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|upregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of activation of funny current by beta-adrenergic receptor signaling pathway|up-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up-regulation of If activation by beta-adrenergic receptor signaling pathway http://purl.obolibrary.org/obo/GO_1903247 GO:1903246 biolink:BiologicalProcess obsolete negative regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate. go-plus.json down regulation of activation of funny current by beta-adrenergic receptor signaling pathway|down regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of activation of funny current by beta-adrenergic receptor signaling pathway|inhibition of If activation by beta-adrenergic receptor signaling pathway|down-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of If activation by beta-adrenergic receptor signaling pathway|inhibition of adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|negative regulation of activation of funny current by beta-adrenergic receptor signaling pathway|downregulation of If activation by beta-adrenergic receptor signaling pathway|downregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|downregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of adrenergic receptor signalling pathway involved in positive regulation of heart rate|inhibition of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of If activation by beta-adrenergic receptor signaling pathway|down-regulation of If activation by beta-adrenergic receptor signaling pathway|down regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of activation of funny current by beta-adrenergic receptor signaling pathway|downregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate http://purl.obolibrary.org/obo/GO_1903246 GO:0014709 biolink:BiologicalProcess positive regulation of somitomeric trunk muscle development Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0014709 GO:1903245 biolink:BiologicalProcess obsolete regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate OBSOLETE. Any process that modulates the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate. go-plus.json regulation of activation of funny current by beta-adrenergic receptor signaling pathway|regulation of If activation by beta-adrenergic receptor signaling pathway|regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate http://purl.obolibrary.org/obo/GO_1903245 GO:0014708 biolink:BiologicalProcess regulation of somitomeric trunk muscle development Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0014708 GO:1903244 biolink:BiologicalProcess positive regulation of cardiac muscle hypertrophy in response to stress Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. go-plus.json upregulation of cardiac muscle hypertrophy in response to stress|activation of cardiac muscle hypertrophy in response to stress|up-regulation of cardiac muscle hypertrophy in response to stress|up regulation of cardiac muscle hypertrophy in response to stress http://purl.obolibrary.org/obo/GO_1903244 GO:0014707 biolink:BiologicalProcess branchiomeric skeletal muscle development The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish. go-plus.json http://purl.obolibrary.org/obo/GO_0014707 CHEBI:133719 biolink:ChemicalSubstance hydroxyoctanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133719 GO:1903254 biolink:BiologicalProcess hercynylselenocysteine metabolic process The chemical reactions and pathways involving hercynylselenocysteine. go-plus.json hercynylselenocysteine metabolism http://purl.obolibrary.org/obo/GO_1903254 UBERON:0011602 biolink:AnatomicalEntity gingiva of lower jaw A gingiva that is part of a lower jaw region. go-plus.json lower jaw gum|lower gum|lower jaw gingiva|lower gingiva|gum of lower jaw|mandibular gum|gum of mandible http://purl.obolibrary.org/obo/UBERON_0011602 GO:1903253 biolink:BiologicalProcess hercynylcysteine sulfoxide biosynthetic process The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide. go-plus.json hercynylcysteine sulfoxide anabolism|hercynylcysteine sulfoxide synthesis|hercynylcysteine sulfoxide biosynthesis|hercynylcysteine sulfoxide formation http://purl.obolibrary.org/obo/GO_1903253 GO:1903252 biolink:BiologicalProcess hercynylcysteine sulfoxide metabolic process The chemical reactions and pathways involving hercynylcysteine sulfoxide. go-plus.json hercynylcysteine sulfoxide metabolism http://purl.obolibrary.org/obo/GO_1903252 UBERON:0011601 biolink:AnatomicalEntity gingiva of upper jaw A gingiva that is part of a upper jaw region. go-plus.json maxillary gum|upper gum|upper jaw gingiva|upper gingiva|gum of upper jaw|gum of maxilla http://purl.obolibrary.org/obo/UBERON_0011601 CHEBI:38468 biolink:ChemicalSubstance indol-3-yl carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38468 GO:1903251 biolink:BiologicalProcess multi-ciliated epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell. go-plus.json multiciliate cell differentiation http://purl.obolibrary.org/obo/GO_1903251 CHEBI:38467 biolink:ChemicalSubstance indolyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38467 GO:1903250 biolink:BiologicalProcess positive regulation of citrulline biosynthetic process Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process. go-plus.json up-regulation of citrulline synthesis|activation of citrulline synthesis|up regulation of citrulline biosynthesis|up regulation of citrulline biosynthetic process|up-regulation of citrulline formation|activation of citrulline formation|activation of citrulline biosynthesis|positive regulation of citrulline biosynthesis|activation of citrulline biosynthetic process|positive regulation of citrulline anabolism|up regulation of citrulline anabolism|positive regulation of citrulline synthesis|up regulation of citrulline synthesis|positive regulation of citrulline formation|up-regulation of citrulline biosynthetic process|up-regulation of citrulline biosynthesis|up regulation of citrulline formation|upregulation of citrulline anabolism|upregulation of citrulline synthesis|upregulation of citrulline biosynthesis|upregulation of citrulline biosynthetic process|upregulation of citrulline formation|up-regulation of citrulline anabolism|activation of citrulline anabolism http://purl.obolibrary.org/obo/GO_1903250 GO:0014702 biolink:CellularComponent free sarcoplasmic reticulum membrane The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0014702 GO:0014701 biolink:CellularComponent junctional sarcoplasmic reticulum membrane The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0014701 GO:0048093 biolink:BiologicalProcess positive regulation of male pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males. go-plus.json up-regulation of male pigmentation|upregulation of male pigmentation|up regulation of male pigmentation|activation of male pigmentation|stimulation of male pigmentation http://purl.obolibrary.org/obo/GO_0048093 CHEBI:38462 biolink:ChemicalSubstance EC 3.1.1.7 (acetylcholinesterase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38462 GO:0048092 biolink:BiologicalProcess negative regulation of male pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males. go-plus.json inhibition of male pigmentation|down regulation of male pigmentation|downregulation of male pigmentation|down-regulation of male pigmentation http://purl.obolibrary.org/obo/GO_0048092 GO:0048091 biolink:BiologicalProcess positive regulation of female pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females. go-plus.json up-regulation of female pigmentation|upregulation of female pigmentation|up regulation of female pigmentation|activation of female pigmentation|stimulation of female pigmentation http://purl.obolibrary.org/obo/GO_0048091 CHEBI:38460 biolink:ChemicalSubstance methylindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38460 GO:0048090 biolink:BiologicalProcess negative regulation of female pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females. go-plus.json inhibition of female pigmentation|down regulation of female pigmentation|downregulation of female pigmentation|down-regulation of female pigmentation http://purl.obolibrary.org/obo/GO_0048090 CHEBI:38466 biolink:ChemicalSubstance imidazolyl carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38466 GO:0048099 biolink:BiologicalProcess anterior/posterior lineage restriction, imaginal disc Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0048099 GO:0048098 biolink:BiologicalProcess antennal joint development The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments. go-plus.json http://purl.obolibrary.org/obo/GO_0048098 GO:0048097 biolink:BiologicalProcess obsolete long-term maintenance of gene activation OBSOLETE. Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term. go-plus.json http://purl.obolibrary.org/obo/GO_0048097 GO:0048096 biolink:BiologicalProcess chromatin-mediated maintenance of transcription Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable. go-plus.json http://purl.obolibrary.org/obo/GO_0048096 GO:0048095 biolink:BiologicalProcess female pigmentation Establishment of a pattern of pigment in females. go-plus.json http://purl.obolibrary.org/obo/GO_0048095 GO:0048094 biolink:BiologicalProcess male pigmentation Establishment of a pattern of pigment in males. go-plus.json http://purl.obolibrary.org/obo/GO_0048094 GO:0014717 biolink:BiologicalProcess regulation of satellite cell activation involved in skeletal muscle regeneration Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. go-plus.json http://purl.obolibrary.org/obo/GO_0014717 GO:0014716 biolink:BiologicalProcess skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt. go-plus.json satellite cell asymmetric division involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014716 GO:0014715 biolink:BiologicalProcess myoblast fate commitment in trunk The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014715 GO:1903259 biolink:BiologicalProcess exon-exon junction complex disassembly The disaggregation of an exon-exon junction complex into its constituent components. go-plus.json EJC disassembly http://purl.obolibrary.org/obo/GO_1903259 GO:0014714 biolink:BiologicalProcess myoblast fate commitment in head The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014714 GO:1903258 biolink:BiologicalProcess sorbose import across plasma membrane The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json sorbose import into cell http://purl.obolibrary.org/obo/GO_1903258 GO:1903257 biolink:BiologicalProcess selenoneine biosynthetic process The chemical reactions and pathways resulting in the formation of selenoneine. go-plus.json L-selenoneine biosynthetic process|selenoneine anabolism|selenoneine synthesis|selenoneine biosynthesis|selenoneine formation http://purl.obolibrary.org/obo/GO_1903257 GO:1903256 biolink:BiologicalProcess selenoneine metabolic process The chemical reactions and pathways involving selenoneine. go-plus.json selenoneine metabolism|L-selenoneine metabolic process http://purl.obolibrary.org/obo/GO_1903256 GO:0014719 biolink:BiologicalProcess skeletal muscle satellite cell activation The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. go-plus.json http://purl.obolibrary.org/obo/GO_0014719 GO:0014718 biolink:BiologicalProcess positive regulation of satellite cell activation involved in skeletal muscle regeneration Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. go-plus.json http://purl.obolibrary.org/obo/GO_0014718 GO:1903255 biolink:BiologicalProcess hercynylselenocysteine biosynthetic process The chemical reactions and pathways resulting in the formation of hercynylselenocysteine. go-plus.json hercynylselenocysteine synthesis|hercynylselenocysteine formation|hercynylselenocysteine biosynthesis|hercynylselenocysteine anabolism http://purl.obolibrary.org/obo/GO_1903255 GO:1903265 biolink:BiologicalProcess positive regulation of tumor necrosis factor-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway. go-plus.json positive regulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of TNF-alpha-mediated signaling pathway|up regulation of tumor necrosis factor alpha-mediated signaling pathway|up regulation of adipocytokine signaling pathway|up-regulation of tumor necrosis factor-mediated signalling pathway|positive regulation of adipocytokine signaling pathway|up regulation of tumor necrosis factor-mediated signaling pathway|up-regulation of TNF-alpha-mediated signaling pathway|activation of adipocytokine signaling pathway|upregulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of tumor necrosis factor-mediated signalling pathway|activation of TNF-alpha-mediated signaling pathway|up-regulation of adipocytokine signaling pathway|upregulation of tumor necrosis factor-mediated signaling pathway|positive regulation of TNF-alpha-mediated signaling pathway|up-regulation of tumor necrosis factor alpha-mediated signaling pathway|up regulation of TNF-alpha-mediated signaling pathway|up regulation of tumor necrosis factor-mediated signalling pathway|upregulation of adipocytokine signaling pathway|positive regulation of tumor necrosis factor-mediated signalling pathway|activation of tumor necrosis factor alpha-mediated signaling pathway|activation of tumor necrosis factor-mediated signalling pathway|up-regulation of tumor necrosis factor-mediated signaling pathway|activation of tumor necrosis factor-mediated signaling pathway http://purl.obolibrary.org/obo/GO_1903265 GO:1903264 biolink:MolecularActivity nitrate reductase activity involved in anaerobic electron transport chain Any nitrate reductase activity that is involved in anaerobic electron transport chain. go-plus.json respiratory nitrate reductase activity involved in anaerobic electron transport chain|nitrite:acceptor oxidoreductase involved in anaerobic electron transport chain|nitrate reductase (acceptor) involved in anaerobic electron transport chain|nitrite:(acceptor) oxidoreductase involved in anaerobic electron transport chain http://purl.obolibrary.org/obo/GO_1903264 GO:1903263 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903263 GO:1903262 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903262 GO:0014713 biolink:BiologicalProcess negative regulation of branchiomeric skeletal muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0014713 GO:1903261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903261 GO:1903260 biolink:BiologicalProcess protein localization to mating projection tip A process in which a protein is transported to, or maintained in, a location within a mating projection tip. go-plus.json protein localization in mating projection tip|protein localization to conjugation tube tip|protein localisation in mating projection tip|protein localization to shmoo tip|protein localisation to mating projection tip http://purl.obolibrary.org/obo/GO_1903260 CHEBI:133720 biolink:ChemicalSubstance glycochenodeoxycholic acid sulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133720 GO:0014712 biolink:BiologicalProcess positive regulation of branchiomeric skeletal muscle development Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0014712 CHEBI:133723 biolink:ChemicalSubstance naphthalene-1,2,4,8-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_133723 chebi_ph7_3 GO:0014711 biolink:BiologicalProcess regulation of branchiomeric skeletal muscle development Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0014711 GO:0014710 biolink:BiologicalProcess negative regulation of somitomeric trunk muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0014710 CHEBI:38472 biolink:ChemicalSubstance acetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_38472 chebi_ph7_3 GO:0097035 biolink:BiologicalProcess regulation of membrane lipid distribution Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0097035 GO:0097034 biolink:BiologicalProcess obsolete mitochondrial respiratory chain complex IV biogenesis OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase complex), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. go-plus.json mitochondrial cytochrome c oxidase complex biogenesis http://purl.obolibrary.org/obo/GO_0097034 GO:0097037 biolink:BiologicalProcess heme export The directed movement of heme out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0097037 GO:0097036 biolink:BiologicalProcess regulation of plasma membrane sterol distribution Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0097036 GO:0097031 biolink:BiologicalProcess obsolete mitochondrial respiratory chain complex I biogenesis OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. go-plus.json http://purl.obolibrary.org/obo/GO_0097031 GO:0097030 biolink:MolecularActivity CENP-A containing nucleosome binding Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3). go-plus.json centromeric nucleosome binding|centromere-specific nucleosome binding http://purl.obolibrary.org/obo/GO_0097030 GO:0097033 biolink:BiologicalProcess obsolete mitochondrial respiratory chain complex III biogenesis OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. go-plus.json mitochondrial cytochrome bc(1) complex biogenesis http://purl.obolibrary.org/obo/GO_0097033 NCBITaxon:2157 biolink:OrganismalEntity Archaea go-plus.json Monera|archaea|prokaryotes|Procaryotae|Metabacteria|Mendosicutes|prokaryote|Prokaryotae|Prokaryota|Archaebacteria http://purl.obolibrary.org/obo/NCBITaxon_2157 GO:0097032 biolink:BiologicalProcess obsolete mitochondrial respiratory chain complex II biogenesis OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex II, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. go-plus.json http://purl.obolibrary.org/obo/GO_0097032 UBERON:0011676 biolink:AnatomicalEntity subdivision of organism along main body axis A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. go-plus.json axial subdivision of organism|main body segment|body segment http://purl.obolibrary.org/obo/UBERON_0011676 GO:1903269 biolink:CellularComponent ornithine carbamoyltransferase inhibitor complex A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity. go-plus.json ornithine carbamoyltransferase arginase complex|OTC-ARGI complex http://purl.obolibrary.org/obo/GO_1903269 GO:1903268 biolink:BiologicalProcess positive regulation of ornithine catabolic process Any process that activates or increases the frequency, rate or extent of ornithine catabolic process. go-plus.json positive regulation of ornithine catabolism|activation of ornithine degradation|positive regulation of ornithine degradation|up regulation of ornithine catabolism|up regulation of ornithine breakdown|activation of ornithine breakdown|positive regulation of ornithine breakdown|up regulation of ornithine catabolic process|activation of ornithine catabolic process|up-regulation of ornithine degradation|upregulation of ornithine catabolism|up-regulation of ornithine breakdown|activation of ornithine catabolism|up-regulation of ornithine catabolism|up-regulation of ornithine catabolic process|upregulation of ornithine degradation|upregulation of ornithine breakdown|upregulation of ornithine catabolic process|up regulation of ornithine degradation http://purl.obolibrary.org/obo/GO_1903268 GO:1903267 biolink:BiologicalProcess negative regulation of ornithine catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process. go-plus.json down regulation of ornithine catabolic process|downregulation of ornithine breakdown|downregulation of ornithine catabolism|negative regulation of ornithine degradation|downregulation of ornithine catabolic process|down-regulation of ornithine degradation|down regulation of ornithine catabolism|negative regulation of ornithine breakdown|down-regulation of ornithine breakdown|inhibition of ornithine catabolism|inhibition of ornithine degradation|down-regulation of ornithine catabolic process|inhibition of ornithine breakdown|inhibition of ornithine catabolic process|down regulation of ornithine degradation|downregulation of ornithine degradation|down-regulation of ornithine catabolism|negative regulation of ornithine catabolism|down regulation of ornithine breakdown http://purl.obolibrary.org/obo/GO_1903267 GO:1903266 biolink:BiologicalProcess regulation of ornithine catabolic process Any process that modulates the frequency, rate or extent of ornithine catabolic process. go-plus.json regulation of ornithine catabolism|regulation of ornithine degradation|regulation of ornithine breakdown http://purl.obolibrary.org/obo/GO_1903266 GO:1903276 biolink:BiologicalProcess regulation of sodium ion export across plasma membrane Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane. go-plus.json regulation of sodium ion export from cell|regulation of sodium export|regulation of sodium ion export http://purl.obolibrary.org/obo/GO_1903276 CHEBI:38448 biolink:ChemicalSubstance trichloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38448 GO:1903275 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903275 GO:1903274 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903274 CHEBI:38445 biolink:ChemicalSubstance chromenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38445 GO:1903273 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903273 GO:1903272 biolink:BiologicalProcess positive regulation of cytoplasmic translational elongation through polyproline stretches Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches. go-plus.json up-regulation of cytoplasmic translational elongation through polyproline stretches|activation of cytoplasmic translational elongation through polyproline stretches|up regulation of cytoplasmic translational elongation through polyproline stretches|upregulation of cytoplasmic translational elongation through polyproline stretches http://purl.obolibrary.org/obo/GO_1903272 GO:1903271 biolink:BiologicalProcess negative regulation of cytoplasmic translational elongation through polyproline stretches Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches. go-plus.json down-regulation of cytoplasmic translational elongation through polyproline stretches|downregulation of cytoplasmic translational elongation through polyproline stretches|down regulation of cytoplasmic translational elongation through polyproline stretches|inhibition of cytoplasmic translational elongation through polyproline stretches http://purl.obolibrary.org/obo/GO_1903271 NCBITaxon:267890 biolink:OrganismalEntity Shewanellaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_267890 GO:1903270 biolink:BiologicalProcess regulation of cytoplasmic translational elongation through polyproline stretches Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches. go-plus.json http://purl.obolibrary.org/obo/GO_1903270 GO:0097039 biolink:BiologicalProcess protein linear polyubiquitination A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein. go-plus.json M1 linkage http://purl.obolibrary.org/obo/GO_0097039 CHEBI:38444 biolink:ChemicalSubstance 2-benzopyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_38444 GO:0097038 biolink:CellularComponent perinuclear endoplasmic reticulum The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes. go-plus.json perinuclear ER http://purl.obolibrary.org/obo/GO_0097038 CHEBI:38443 biolink:ChemicalSubstance 1-benzopyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_38443 CHEBI:7027 biolink:ChemicalSubstance 2-amino-3-O-[(R)-1-carboxyethyl]-2-deoxy-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_7027 GO:0097046 biolink:BiologicalProcess replication fork progression beyond termination site Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks. go-plus.json http://purl.obolibrary.org/obo/GO_0097046 GO:0097045 biolink:BiologicalProcess phosphatidylserine exposure on blood platelet A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system. go-plus.json http://purl.obolibrary.org/obo/GO_0097045 GO:0097048 biolink:BiologicalProcess dendritic cell apoptotic process Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. go-plus.json dendritic cell apoptosis http://purl.obolibrary.org/obo/GO_0097048 GO:0097047 biolink:CellularComponent DNA replication termination region A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks. go-plus.json TER http://purl.obolibrary.org/obo/GO_0097047 GO:0097042 biolink:CellularComponent extrinsic component of fungal-type vacuolar membrane The component of a fungal-type vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to fungal-type vacuolar membrane http://purl.obolibrary.org/obo/GO_0097042 GO:0097041 biolink:BiologicalProcess phenolic phthiocerol biosynthetic process The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position. go-plus.json phenolphthiocerol biosynthesis|phenolic phthiocerol anabolism|phenolic phthiocerol synthesis|phenolic phthiocerol formation|phenolic phthiocerol biosynthesis http://purl.obolibrary.org/obo/GO_0097041 GO:0097044 biolink:BiologicalProcess histone H3-K56 acetylation in response to DNA damage The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone as a result of the detection of DNA damage within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097044 GO:0097043 biolink:BiologicalProcess histone H3-K56 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0097043 GO:0097040 biolink:BiologicalProcess phthiocerol biosynthetic process The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents. go-plus.json phthiocerol anabolism|phthiocerol biosynthesis|phthiocerol synthesis|phthiocerol formation http://purl.obolibrary.org/obo/GO_0097040 GO:1903279 biolink:BiologicalProcess regulation of calcium:sodium antiporter activity Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity. go-plus.json regulation of sodium:calcium exchange|regulation of mitochondrial sodium/calcium ion exchange|regulation of sodium/calcium exchanger http://purl.obolibrary.org/obo/GO_1903279 GO:1903278 biolink:BiologicalProcess positive regulation of sodium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane. go-plus.json up-regulation of sodium ion export|upregulation of sodium export|up-regulation of sodium ion export from cell|positive regulation of sodium ion export|activation of sodium export|positive regulation of sodium ion export from cell|upregulation of sodium ion export|up regulation of sodium export|upregulation of sodium ion export from cell|positive regulation of sodium export|activation of sodium ion export|up regulation of sodium ion export|up regulation of sodium ion export from cell|up-regulation of sodium export|activation of sodium ion export from cell http://purl.obolibrary.org/obo/GO_1903278 GO:1903277 biolink:BiologicalProcess negative regulation of sodium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane. go-plus.json inhibition of sodium ion export from cell|down regulation of sodium export|downregulation of sodium export|negative regulation of sodium ion export|down regulation of sodium ion export|negative regulation of sodium ion export from cell|down regulation of sodium ion export from cell|downregulation of sodium ion export|negative regulation of sodium export|down-regulation of sodium export|inhibition of sodium export|downregulation of sodium ion export from cell|down-regulation of sodium ion export|inhibition of sodium ion export|down-regulation of sodium ion export from cell http://purl.obolibrary.org/obo/GO_1903277 GO:1903287 biolink:BiologicalProcess negative regulation of potassium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane. go-plus.json down regulation of potassium import|inhibition of potassium ion uptake|downregulation of potassium ion import|downregulation of potassium ion uptake|down regulation of potassium ion import|down regulation of potassium ion uptake|negative regulation of potassium ion import|negative regulation of potassium import|down-regulation of potassium import|inhibition of potassium import|down-regulation of potassium ion import|downregulation of potassium import|down-regulation of potassium ion uptake|negative regulation of potassium ion uptake|inhibition of potassium ion import http://purl.obolibrary.org/obo/GO_1903287 CHEBI:38459 biolink:ChemicalSubstance oxindoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_38459 CHEBI:14469 biolink:ChemicalSubstance isomethyleugenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_14469 chebi_ph7_3 GO:1903286 biolink:BiologicalProcess regulation of potassium ion import Any process that modulates the frequency, rate or extent of potassium ion import. go-plus.json regulation of potassium import|regulation of potassium ion uptake http://purl.obolibrary.org/obo/GO_1903286 GO:1903285 biolink:BiologicalProcess positive regulation of hydrogen peroxide catabolic process Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process. go-plus.json activation of detoxification of hydrogen peroxide|up regulation of hydrogen peroxide removal|up-regulation of H2O2 scavenging|upregulation of hydrogen peroxide catabolic process|activation of detoxification of H2O2|positive regulation of hydrogen peroxide removal|up regulation of hydrogen peroxide degradation|activation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide degradation|activation of hydrogen peroxide catabolism|up-regulation of hydrogen peroxide catabolism|up-regulation of detoxification of hydrogen peroxide|up-regulation of H2O2 catabolic process|activation of H2O2 catabolic process|upregulation of hydrogen peroxide scavenging|positive regulation of detoxification of H2O2|up regulation of hydrogen peroxide breakdown|activation of hydrogen peroxide removal|activation of hydrogen peroxide breakdown|up regulation of detoxification of H2O2|positive regulation of hydrogen peroxide breakdown|upregulation of H2O2 scavenging|up regulation of hydrogen peroxide catabolic process|activation of hydrogen peroxide catabolic process|upregulation of detoxification of hydrogen peroxide|up-regulation of hydrogen peroxide removal|up-regulation of hydrogen peroxide scavenging|up-regulation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide catabolism|positive regulation of H2O2 catabolic process|up regulation of hydrogen peroxide catabolism|upregulation of detoxification of H2O2|up regulation of H2O2 catabolic process|activation of hydrogen peroxide scavenging|up regulation of H2O2 scavenging|up-regulation of hydrogen peroxide breakdown|upregulation of hydrogen peroxide removal|positive regulation of H2O2 scavenging|up regulation of detoxification of hydrogen peroxide|upregulation of hydrogen peroxide degradation|up-regulation of hydrogen peroxide catabolic process|positive regulation of detoxification of hydrogen peroxide|positive regulation of hydrogen peroxide scavenging|upregulation of hydrogen peroxide catabolism|activation of H2O2 scavenging|up-regulation of detoxification of H2O2|up regulation of hydrogen peroxide scavenging|upregulation of H2O2 catabolic process|upregulation of hydrogen peroxide breakdown http://purl.obolibrary.org/obo/GO_1903285 GO:1903284 biolink:BiologicalProcess positive regulation of glutathione peroxidase activity Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity. go-plus.json up-regulation of GSH peroxidase activity|up regulation of selenium-glutathione peroxidase activity|upregulation of glutathione:hydrogen-peroxide oxidoreductase activity|up regulation of glutathione peroxidase activity|up-regulation of non-selenium glutathione peroxidase activity|up regulation of reduced glutathione peroxidase activity|activation of glutathione peroxidase activity|positive regulation of reduced glutathione peroxidase activity|activation of reduced glutathione peroxidase activity|activation of non-selenium glutathione peroxidase activity|upregulation of GSH peroxidase activity|upregulation of selenium-glutathione peroxidase activity|up regulation of glutathione:hydrogen-peroxide oxidoreductase activity|positive regulation of non-selenium glutathione peroxidase activity|positive regulation of glutathione:hydrogen-peroxide oxidoreductase activity|activation of glutathione:hydrogen-peroxide oxidoreductase activity|up-regulation of glutathione peroxidase activity|up regulation of non-selenium glutathione peroxidase activity|up-regulation of reduced glutathione peroxidase activity|up-regulation of selenium-glutathione peroxidase activity|up regulation of GSH peroxidase activity|activation of selenium-glutathione peroxidase activity|positive regulation of GSH peroxidase activity|activation of GSH peroxidase activity|upregulation of glutathione peroxidase activity|enhancement of GPX activity|upregulation of non-selenium glutathione peroxidase activity|up-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|upregulation of reduced glutathione peroxidase activity|positive regulation of selenium-glutathione peroxidase activity http://purl.obolibrary.org/obo/GO_1903284 GO:1903283 biolink:BiologicalProcess negative regulation of glutathione peroxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity. go-plus.json inhibition of GSH peroxidase activity|downregulation of reduced glutathione peroxidase activity|downregulation of selenium-glutathione peroxidase activity|down regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down regulation of selenium-glutathione peroxidase activity|negative regulation of non-selenium glutathione peroxidase activity|down-regulation of glutathione peroxidase activity|down-regulation of non-selenium glutathione peroxidase activity|inhibition of selenium-glutathione peroxidase activity|downregulation of glutathione:hydrogen-peroxide oxidoreductase activity|negative regulation of reduced glutathione peroxidase activity|down-regulation of reduced glutathione peroxidase activity|down regulation of GSH peroxidase activity|inhibition of glutathione peroxidase activity|inhibition of reduced glutathione peroxidase activity|downregulation of GSH peroxidase activity|downregulation of non-selenium glutathione peroxidase activity|negative regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down regulation of non-selenium glutathione peroxidase activity|inhibition of glutathione:hydrogen-peroxide oxidoreductase activity|down-regulation of GSH peroxidase activity|negative regulation of GSH peroxidase activity|negative regulation of selenium-glutathione peroxidase activity|down-regulation of selenium-glutathione peroxidase activity|down regulation of glutathione peroxidase activity|inhibition of non-selenium glutathione peroxidase activity|down regulation of reduced glutathione peroxidase activity|downregulation of glutathione peroxidase activity http://purl.obolibrary.org/obo/GO_1903283 GO:1903282 biolink:BiologicalProcess regulation of glutathione peroxidase activity Any process that modulates the frequency, rate or extent of glutathione peroxidase activity. go-plus.json regulation of selenium-glutathione peroxidase activity|regulation of glutathione:hydrogen-peroxide oxidoreductase activity|regulation of GSH peroxidase activity|regulation of non-selenium glutathione peroxidase activity|regulation of reduced glutathione peroxidase activity http://purl.obolibrary.org/obo/GO_1903282 GO:1903281 biolink:BiologicalProcess positive regulation of calcium:sodium antiporter activity Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity. go-plus.json upregulation of calcium:sodium antiporter activity|activation of sodium:calcium exchange|upregulation of sodium/calcium exchanger|up regulation of mitochondrial sodium/calcium ion exchange|positive regulation of mitochondrial sodium/calcium ion exchange|up-regulation of sodium:calcium exchange|activation of mitochondrial sodium/calcium ion exchange|up-regulation of calcium:sodium antiporter activity|activation of calcium:sodium antiporter activity|up-regulation of sodium/calcium exchanger|activation of sodium/calcium exchanger|up-regulation of mitochondrial sodium/calcium ion exchange|upregulation of sodium:calcium exchange|positive regulation of sodium/calcium exchanger|up regulation of calcium:sodium antiporter activity|upregulation of mitochondrial sodium/calcium ion exchange|up regulation of sodium/calcium exchanger|up regulation of sodium:calcium exchange|positive regulation of sodium:calcium exchange http://purl.obolibrary.org/obo/GO_1903281 GO:1903280 biolink:BiologicalProcess negative regulation of calcium:sodium antiporter activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity. go-plus.json negative regulation of mitochondrial sodium/calcium ion exchange|down-regulation of mitochondrial sodium/calcium ion exchange|inhibition of sodium:calcium exchange|down-regulation of calcium:sodium antiporter activity|negative regulation of sodium/calcium exchanger|down-regulation of sodium/calcium exchanger|down regulation of sodium:calcium exchange|inhibition of mitochondrial sodium/calcium ion exchange|downregulation of sodium:calcium exchange|downregulation of calcium:sodium antiporter activity|down regulation of mitochondrial sodium/calcium ion exchange|downregulation of sodium/calcium exchanger|down regulation of calcium:sodium antiporter activity|downregulation of mitochondrial sodium/calcium ion exchange|down regulation of sodium/calcium exchanger|down-regulation of sodium:calcium exchange|negative regulation of sodium:calcium exchange|inhibition of calcium:sodium antiporter activity|inhibition of sodium/calcium exchanger http://purl.obolibrary.org/obo/GO_1903280 GO:0097049 biolink:BiologicalProcess motor neuron apoptotic process Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. go-plus.json motor neuron apoptosis|motoneuron apoptosis http://purl.obolibrary.org/obo/GO_0097049 GO:0097013 biolink:CellularComponent phagocytic vesicle lumen The volume enclosed by the membrane of a phagocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097013 GO:0097012 biolink:BiologicalProcess response to granulocyte macrophage colony-stimulating factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus. go-plus.json response to granulocyte macrophage colony-stimulating factor stimulus|response to GM-CSF http://purl.obolibrary.org/obo/GO_0097012 GO:0097015 biolink:CellularComponent obsolete bacterial-type flagellar cytoplasm OBSOLETE. All of the contents of a bacterial-type flagellum, excluding the plasma membrane surrounding the flagellum. go-plus.json bacterial-type flagellum cytoplasm http://purl.obolibrary.org/obo/GO_0097015 GO:0097014 biolink:CellularComponent ciliary plasm All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. go-plus.json microtubule-based flagellar cytoplasm|microtubule-based flagellar matrix|cilium cytoplasm|microtubule-based flagellum matrix|cilium plasm|cilial cytoplasm|microtubule-based flagellum cytoplasm|ciliary cytoplasm http://purl.obolibrary.org/obo/GO_0097014 GO:0097011 biolink:BiologicalProcess cellular response to granulocyte macrophage colony-stimulating factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus. go-plus.json cellular response to GM-CSF stimulus http://purl.obolibrary.org/obo/GO_0097011 GO:0097010 biolink:BiologicalProcess eukaryotic translation initiation factor 4F complex assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex. go-plus.json eIF4F assembly|eIF-4F assembly http://purl.obolibrary.org/obo/GO_0097010 GO:1903289 biolink:BiologicalProcess obsolete regulation of ATP catabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of ATP catabolic process. go-plus.json regulation of ATP degradation|regulation of ATP breakdown|regulation of ATP catabolism|regulation of ATP hydrolysis http://purl.obolibrary.org/obo/GO_1903289 UBERON:2001950 biolink:AnatomicalEntity inter-premaxillary joint Joint that articulates the left and right premaxillary bones. Inter-premaxillary joint is unpaired. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001950 GO:1903288 biolink:BiologicalProcess positive regulation of potassium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane. go-plus.json upregulation of potassium ion import|up-regulation of potassium import|activation of potassium import|upregulation of potassium ion uptake|up-regulation of potassium ion import|activation of potassium ion import|up-regulation of potassium ion uptake|positive regulation of potassium import|activation of potassium ion uptake|up regulation of potassium import|positive regulation of potassium ion import|up regulation of potassium ion import|positive regulation of potassium ion uptake|upregulation of potassium import|up regulation of potassium ion uptake http://purl.obolibrary.org/obo/GO_1903288 GO:1903298 biolink:BiologicalProcess negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway. go-plus.json protection against hypoxia-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to hypoxia|inhibition of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway|down-regulation of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of hypoxia-induced apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to hypoxia http://purl.obolibrary.org/obo/GO_1903298 CHEBI:38426 biolink:ChemicalSubstance (2E,4Z)-5-carboxy-2,4,5-trichloropenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38426 GO:1903297 biolink:BiologicalProcess regulation of hypoxia-induced intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway. go-plus.json regulation of intrinsic apoptotic signaling pathway in response to hypoxia|regulation of hypoxia-induced apoptosis|regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1903297 CHEBI:38425 biolink:ChemicalSubstance 2,5-dichloromuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_38425 chebi_ph7_3 GO:1903296 biolink:BiologicalProcess positive regulation of glutamate secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter. go-plus.json upregulation of glutamate secretion, neurotransmission|up-regulation of glutamate secretion, neurotransmission|activation of glutamate secretion, neurotransmission|up regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_1903296 CHEBI:38424 biolink:ChemicalSubstance dichloromuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_38424 GO:1903295 biolink:BiologicalProcess negative regulation of glutamate secretion, neurotransmission Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission. go-plus.json down regulation of glutamate secretion, neurotransmission|inhibition of glutamate secretion, neurotransmission|down-regulation of glutamate secretion, neurotransmission|downregulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_1903295 GO:1903294 biolink:BiologicalProcess regulation of glutamate secretion, neurotransmission Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission. go-plus.json http://purl.obolibrary.org/obo/GO_1903294 GO:1903293 biolink:CellularComponent phosphatase complex A protein complex which is capable of phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903293 CHEBI:38429 biolink:ChemicalSubstance monochloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38429 GO:1903292 biolink:BiologicalProcess protein localization to Golgi membrane A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. go-plus.json protein localization in Golgi membrane|protein localisation to Golgi membrane|protein localisation in Golgi membrane http://purl.obolibrary.org/obo/GO_1903292 CHEBI:38428 biolink:ChemicalSubstance 3-chloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38428 GO:1903291 biolink:BiologicalProcess obsolete positive regulation of ATP catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP catabolic process. go-plus.json up regulation of ATP catabolic process|positive regulation of ATP hydrolysis|activation of ATP catabolic process|up regulation of ATP hydrolysis|upregulation of ATP catabolism|up-regulation of ATP degradation|up-regulation of ATP breakdown|up-regulation of ATP catabolism|activation of ATP catabolism|upregulation of ATP hydrolysis|up-regulation of ATP catabolic process|upregulation of ATP degradation|upregulation of ATP breakdown|up-regulation of ATP hydrolysis|upregulation of ATP catabolic process|positive regulation of ATP catabolism|up regulation of ATP degradation|up regulation of ATP catabolism|positive regulation of ATP degradation|activation of ATP degradation|activation of ATP hydrolysis|up regulation of ATP breakdown|activation of ATP breakdown|positive regulation of ATP breakdown http://purl.obolibrary.org/obo/GO_1903291 UBERON:0011648 biolink:AnatomicalEntity jaw muscle go-plus.json mandibular muscles|mandibular muscle http://purl.obolibrary.org/obo/UBERON_0011648 CHEBI:38427 biolink:ChemicalSubstance 2,3,5-trichloro-cis,cis-muconate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_38427 GO:1903290 biolink:BiologicalProcess obsolete negative regulation of ATP catabolic process OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP catabolic process. go-plus.json inhibition of ATP catabolism|down-regulation of ATP breakdown|negative regulation of ATP breakdown|inhibition of ATP degradation|downregulation of ATP hydrolysis|down-regulation of ATP catabolic process|down regulation of ATP hydrolysis|inhibition of ATP breakdown|inhibition of ATP catabolic process|down regulation of ATP degradation|inhibition of ATP hydrolysis|down-regulation of ATP catabolism|negative regulation of ATP catabolism|downregulation of ATP degradation|down regulation of ATP breakdown|down regulation of ATP catabolic process|downregulation of ATP breakdown|downregulation of ATP catabolism|negative regulation of ATP hydrolysis|down-regulation of ATP hydrolysis|down-regulation of ATP degradation|negative regulation of ATP degradation|downregulation of ATP catabolic process|down regulation of ATP catabolism http://purl.obolibrary.org/obo/GO_1903290 GO:0097017 biolink:BiologicalProcess renal protein absorption A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). go-plus.json http://purl.obolibrary.org/obo/GO_0097017 CHEBI:38422 biolink:ChemicalSubstance dichloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38422 GO:0097016 biolink:MolecularActivity L27 domain binding Binding to a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner. go-plus.json http://purl.obolibrary.org/obo/GO_0097016 CHEBI:38421 biolink:ChemicalSubstance 2,5-dichloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38421 GO:0097019 biolink:BiologicalProcess neurotransmitter receptor catabolic process The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors. go-plus.json neurotransmitter receptor degradation|neurotransmitter receptor catabolism|neurotransmitter receptor breakdown http://purl.obolibrary.org/obo/GO_0097019 GO:0097018 biolink:BiologicalProcess renal albumin absorption A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0097018 GO:0097024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097024 GO:0097023 biolink:MolecularActivity fructose 6-phosphate aldolase activity Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate. RHEA:28002 go-plus.json http://purl.obolibrary.org/obo/GO_0097023 GO:0097026 biolink:BiologicalProcess dendritic cell dendrite assembly Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. go-plus.json dendritic extension http://purl.obolibrary.org/obo/GO_0097026 GO:0097025 biolink:CellularComponent MPP7-DLG1-LIN7 complex A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0097025 GO:0097020 biolink:MolecularActivity COPII receptor activity Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0097020 GO:0097022 biolink:BiologicalProcess lymphocyte migration into lymph node The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen. go-plus.json lymphocyte homing http://purl.obolibrary.org/obo/GO_0097022 GO:0097021 biolink:BiologicalProcess lymphocyte migration into lymphoid organs The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen. go-plus.json lymphocyte homing http://purl.obolibrary.org/obo/GO_0097021 UBERON:0011642 biolink:AnatomicalEntity oral epithelium from ectoderm An epithelium that develops_from a ectoderm and is part of a oral epithelium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011642 GO:1903299 biolink:BiologicalProcess regulation of hexokinase activity Any process that modulates the frequency, rate or extent of hexokinase activity. go-plus.json regulation of hexokinase type IV (glucokinase) activity|regulation of hexokinase type II activity|regulation of hexokinase type I activity|regulation of hexokinase type III activity|regulation of glucose ATP phosphotransferase activity|regulation of hexokinase type IV|regulation of hexokinase (phosphorylating)|regulation of ATP-dependent hexokinase activity|regulation of hexokinase type IV glucokinase activity|regulation of hexokinase D|regulation of ATP:D-hexose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_1903299 CHEBI:38436 biolink:ChemicalSubstance muconic semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_38436 UBERON:0011634 biolink:AnatomicalEntity ectopterygoid bone A palatal bone which -- like many palatal bones -- may originally have developed as a dermal bone replacing part of the palatoquadrate, the primitive upper jaw. Like the palatine (also called dermopalatine), the ectopterygoid replaces the middle part of the autopalatine. It may be serially homologous with the palatine(s), but is somewhat specialized, being the last (most posterior in palatal view) of the series and bordering the fossa for the jaw muscles. In a typical tetrapod it abuts the palatine anteriorly, the maxilla laterally, the pterygoid or the fossa mandubuaris medially, and the fossa posteriorly go-plus.json ectopterygoids|ectopterygoid http://purl.obolibrary.org/obo/UBERON_0011634 CHEBI:38434 biolink:ChemicalSubstance 2-chloromuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38434 GO:0097028 biolink:BiologicalProcess dendritic cell differentiation The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_0097028 GO:0097027 biolink:MolecularActivity ubiquitin-protein transferase activator activity Binds to and increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein. go-plus.json http://purl.obolibrary.org/obo/GO_0097027 GO:0097029 biolink:BiologicalProcess mature conventional dendritic cell differentiation The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. go-plus.json http://purl.obolibrary.org/obo/GO_0097029 GO:0000046 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000046 GO:0000045 biolink:BiologicalProcess autophagosome assembly The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. go-plus.json autophagic vacuole formation|PAS formation|autophagic vacuole assembly|autophagosome biosynthesis|autophagosome formation http://purl.obolibrary.org/obo/GO_0000045 GO:0000044 biolink:BiologicalProcess obsolete ascorbate stabilization OBSOLETE. The reduction of the ascorbate free radical to a stable form. go-plus.json vitamin C stabilization|ascorbate stabilization http://purl.obolibrary.org/obo/GO_0000044 GO:0000043 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000043 GO:0000049 biolink:MolecularActivity tRNA binding Binding to a transfer RNA. go-plus.json base pairing with tRNA http://purl.obolibrary.org/obo/GO_0000049 GO:0000048 biolink:MolecularActivity peptidyltransferase activity Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). EC:2.3.2.12|Reactome:R-HSA-156912|MetaCyc:PEPTIDYLTRANSFERASE-RXN go-plus.json peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity http://purl.obolibrary.org/obo/GO_0000048 GO:0000047 biolink:MolecularActivity obsolete Rieske iron-sulfur protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json Rieske iron-sulfur protein|Rieske iron-sulphur protein http://purl.obolibrary.org/obo/GO_0000047 CHEBI:167116 biolink:ChemicalSubstance oxidized 1-acyl-sn-glycero-3-phosphocholine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_167116 CHEBI:167119 biolink:ChemicalSubstance oxidized 2-acyl-sn-glycero-3-phosphocholine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_167119 CHEBI:167118 biolink:ChemicalSubstance oxidized N-(fatty acyl)-ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_167118 PR:000001391 biolink:Protein interleukin-4 A protein that is a translation product of the human IL4 gene or a 1:1 ortholog thereof. go-plus.json B-cell stimulatory factor 1|binetrakin|IL-4|IGG1 induction factor|B-cell growth factor 1|lymphocyte stimulatory factor 1|BSF-1|pitrakinra|B-cell IgG differentiation factor|IL4 http://purl.obolibrary.org/obo/PR_000001391 GO:0000042 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000042 GO:0000041 biolink:BiologicalProcess transition metal ion transport The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. go-plus.json transition metal transport http://purl.obolibrary.org/obo/GO_0000041 PR:000001393 biolink:Protein interleukin-6 A protein that is a translation product of the human IL6 gene or a 1:1 ortholog thereof. go-plus.json CTL differentiation factor|hybridoma growth factor|B-cell stimulatory factor 2|IL-6|CDF|interferon beta-2|interleukin HP-1|B-cell hybridoma growth factor|IFNB2|BSF-2|IL6|IFN-beta-2 http://purl.obolibrary.org/obo/PR_000001393 GO:0000040 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000040 CHEBI:167115 biolink:ChemicalSubstance oxidized glycerophosphocholine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_167115 PR:000001392 biolink:Protein interleukin-5 A protein that is a translation product of the human IL5 gene or a 1:1 ortholog thereof. go-plus.json eosinophil differentiation factor|BCGF-II|B-cell growth factor II|cytotoxic T-lymphocyte inducer|IL-5|TRF|B-cell differentiation factor I|T-cell replacing factor|IL5 http://purl.obolibrary.org/obo/PR_000001392 CHEBI:167114 biolink:ChemicalSubstance 2-hydroxydicarboxylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_167114 PR:000001383 biolink:Protein interleukin-22 A protein that is a translation product of the human IL22 gene or a 1:1 ortholog thereof. go-plus.json IL-10-related T-cell-derived-inducible factor|Il22a|cytokine Zcyto18|IL-22a|Iltifa|ZCYTO18|IL-22|ILTIF|IL-TIF|IL-TIF alpha|interleukin-22a|IL22 http://purl.obolibrary.org/obo/PR_000001383 SO:0000837 biolink:SequenceFeature UTR_region A region of UTR. go-plus.json UTR region http://purl.obolibrary.org/obo/SO_0000837 SOFA PR:000001387 biolink:Protein interleukin-3 A protein that is a translation product of the human IL3 gene or a 1:1 ortholog thereof. go-plus.json Csfmu|MCGF|multipotential colony-stimulating factor|IL3|mast cell growth factor|hematopoietic growth factor|P-cell-stimulating factor|IL-3 http://purl.obolibrary.org/obo/PR_000001387 SO:0000836 biolink:SequenceFeature mRNA_region A region of an mRNA. go-plus.json mRNA region http://purl.obolibrary.org/obo/SO_0000836 SOFA SO:0000839 biolink:SequenceFeature polypeptide_region Biological sequence region that can be assigned to a specific subsequence of a polypeptide. go-plus.json site|region or site annotation|positional|positional polypeptide feature|region http://purl.obolibrary.org/obo/SO_0000839 biosapiens|SOFA PR:000001389 biolink:Protein interleukin-33 A protein that is a translation product of the human IL33 gene or a 1:1 ortholog thereof. go-plus.json NF-HEV|IL33|IL-1F11|NFHEV|interleukin-1 family member 11|IL1F11|C9orf26|nuclear factor from high endothelial venules|IL-33 http://purl.obolibrary.org/obo/PR_000001389 SO:0000833 biolink:SequenceFeature transcript_region A region of a transcript. go-plus.json transcript region http://purl.obolibrary.org/obo/SO_0000833 SOFA SO:0000835 biolink:SequenceFeature primary_transcript_region A part of a primary transcript. go-plus.json primary transcript region http://purl.obolibrary.org/obo/SO_0000835 SOFA SO:0000834 biolink:SequenceFeature mature_transcript_region A region of a mature transcript. go-plus.json mature transcript region http://purl.obolibrary.org/obo/SO_0000834 SOFA SO:0000831 biolink:SequenceFeature gene_member_region A region of a gene. go-plus.json gene member region http://purl.obolibrary.org/obo/SO_0000831 SOFA SO:0000830 biolink:SequenceFeature chromosome_part A region of a chromosome. go-plus.json chromosome part|chromosomal_region|chromosomal region http://purl.obolibrary.org/obo/SO_0000830 SOFA GO:0000057 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000057 CHEBI:167120 biolink:ChemicalSubstance oxidized 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_167120 GO:0000056 biolink:BiologicalProcess ribosomal small subunit export from nucleus The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm. go-plus.json ribosomal small subunit-nucleus export|ribosomal small subunit export out of nucleus|40S ribosomal subunit export from nucleus|30S ribosomal subunit export from nucleus|ribosomal small subunit export from cell nucleus|ribosomal small subunit transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0000056 GO:0000055 biolink:BiologicalProcess ribosomal large subunit export from nucleus The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm. go-plus.json ribosomal large subunit transport from nucleus to cytoplasm|ribosomal large subunit export from cell nucleus|60S ribosomal subunit export from nucleus|50S ribosomal subunit export from nucleus|ribosomal large subunit export out of nucleus|ribosomal large subunit-nucleus export http://purl.obolibrary.org/obo/GO_0000055 GO:0000054 biolink:BiologicalProcess ribosomal subunit export from nucleus The directed movement of a ribosomal subunit from the nucleus into the cytoplasm. go-plus.json ribosomal subunit transport from nucleus to cytoplasm|ribosomal subunit export out of nucleus|ribosomal subunit export from cell nucleus|ribosome export from nucleus|ribosomal subunit-nucleus export http://purl.obolibrary.org/obo/GO_0000054 goslim_yeast CHEBI:167121 biolink:ChemicalSubstance oxidized 2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_167121 GO:0000059 biolink:BiologicalProcess obsolete protein import into nucleus, docking OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex. go-plus.json protein docking during protein-nucleus import|protein docking during protein import into nucleus|protein-nucleus import, docking|protein transport from cytoplasm to nucleus, docking|protein docking during protein transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0000059 GO:0000058 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000058 CHEBI:87373 biolink:ChemicalSubstance pentyl propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87373 chebi_ph7_3 CHEBI:143136 biolink:ChemicalSubstance succinamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_143136 chebi_ph7_3 GO:0000053 biolink:BiologicalProcess argininosuccinate metabolic process The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate. go-plus.json argininosuccinate metabolism http://purl.obolibrary.org/obo/GO_0000053 GO:0000052 biolink:BiologicalProcess citrulline metabolic process The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. go-plus.json citrulline metabolism http://purl.obolibrary.org/obo/GO_0000052 GO:0000051 biolink:BiologicalProcess obsolete urea cycle intermediate metabolic process OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea. go-plus.json urea cycle intermediate metabolic process|urea cycle intermediate metabolism http://purl.obolibrary.org/obo/GO_0000051 GO:0000050 biolink:BiologicalProcess urea cycle The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. Wikipedia:Urea_cycle go-plus.json ornithine cycle|urea biosynthesis|urea biosynthetic process http://purl.obolibrary.org/obo/GO_0000050 PR:000001395 biolink:Protein interleukin-8 A protein that is a translation product of the human CXCL8 gene or a 1:1 ortholog thereof. go-plus.json IL8|IL-8|protein 3-10C|emoctakin|neutrophil-activating protein 1|C-X-C motif chemokine 8|NAP-1|monocyte-derived neutrophil chemotactic factor|MONAP|MDNCF|monocyte-derived neutrophil-activating peptide|CXCL8|T-cell chemotactic factor|granulocyte chemotactic protein 1|GCP-1 http://purl.obolibrary.org/obo/PR_000001395 CHEBI:157772 biolink:ChemicalSubstance epoxydocosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_157772 CHEBI:157771 biolink:ChemicalSubstance hydroperoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_157771 PR:000025350 biolink:Protein HSPC protein An Hsp70 family chaperone that contains an ATPase and HSP90 domains. go-plus.json HSP90 http://purl.obolibrary.org/obo/PR_000025350 PR:000001397 biolink:Protein interleukin-9 receptor A protein that is a translation product of the human IL9R gene or a 1:1 ortholog thereof. go-plus.json IL-9 receptor|IL-9R|IL9R|CD129 http://purl.obolibrary.org/obo/PR_000001397 CHEBI:157770 biolink:ChemicalSubstance short-chain primary fatty alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_157770 chebi_ph7_3 PR:000001396 biolink:Protein interleukin-9 A protein that is a translation product of the human IL9 gene or a 1:1 ortholog thereof. go-plus.json IL-9|T-cell growth factor P40|IL9|cytokine P40 http://purl.obolibrary.org/obo/PR_000001396 CHEBI:157775 biolink:ChemicalSubstance N-acyl-beta-D-galactosylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_157775 chebi_ph7_3 CHEBI:157774 biolink:ChemicalSubstance epoxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_157774 CHEBI:157773 biolink:ChemicalSubstance epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_157773 GO:0000024 biolink:BiologicalProcess maltose biosynthetic process The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose). go-plus.json maltose anabolism|malt sugar biosynthesis|malt sugar biosynthetic process|maltose synthesis|maltose formation|maltose biosynthesis http://purl.obolibrary.org/obo/GO_0000024 GO:0048002 biolink:BiologicalProcess antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. go-plus.json peptide antigen processing and presentation|antigen presentation, peptide antigen http://purl.obolibrary.org/obo/GO_0048002 GO:0048001 biolink:MolecularActivity erythrose-4-phosphate dehydrogenase activity Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH. KEGG_REACTION:R01825|EC:1.2.1.72|RHEA:12056|MetaCyc:ERYTH4PDEHYDROG-RXN go-plus.json E4P dehydrogenase activity|GapB|erythrose 4-phosphate dehydrogenase activity|D-erythrose 4-phosphate:NAD+ oxidoreductase activity|E4PDH|Epd dehydrogenase activity http://purl.obolibrary.org/obo/GO_0048001 GO:0000023 biolink:BiologicalProcess maltose metabolic process The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch. go-plus.json malt sugar metabolism|malt sugar metabolic process|maltose metabolism http://purl.obolibrary.org/obo/GO_0000023 GO:0000022 biolink:BiologicalProcess mitotic spindle elongation The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B. go-plus.json microtubule sliding involved in mitotic spindle elongation|spindle elongation during mitosis http://purl.obolibrary.org/obo/GO_0000022 GO:0048000 biolink:MolecularActivity isoflavone 3'-hydroxylase activity Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O. EC:1.14.14.88|MetaCyc:RXN-3762|RHEA:22960 go-plus.json isoflavone 3'-monooxygenase activity|formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating) http://purl.obolibrary.org/obo/GO_0048000 GO:0000021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000021 GO:0000028 biolink:BiologicalProcess ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit. go-plus.json 30S ribosomal subunit assembly|40S ribosomal subunit assembly http://purl.obolibrary.org/obo/GO_0000028 GO:0000027 biolink:BiologicalProcess ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. go-plus.json 50S ribosomal subunit assembly|60S ribosomal subunit assembly http://purl.obolibrary.org/obo/GO_0000027 GO:0000026 biolink:MolecularActivity alpha-1,2-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage. Reactome:R-HSA-4720478|Reactome:R-HSA-4551297|Reactome:R-HSA-446187|Reactome:R-HSA-446215|Reactome:R-HSA-446216|Reactome:R-HSA-9035514 go-plus.json http://purl.obolibrary.org/obo/GO_0000026 CHEBI:7051 biolink:ChemicalSubstance myosmine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7051 chebi_ph7_3 GO:0000025 biolink:BiologicalProcess maltose catabolic process The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose). MetaCyc:MALTOSECAT-PWY go-plus.json maltose hydrolysis|malt sugar catabolism|malt sugar catabolic process|maltose degradation|maltose breakdown http://purl.obolibrary.org/obo/GO_0000025 GO:0048009 biolink:BiologicalProcess insulin-like growth factor receptor signaling pathway The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands. go-plus.json IGF receptor signaling pathway|IGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0048009 GO:0048008 biolink:BiologicalProcess platelet-derived growth factor receptor signaling pathway The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. go-plus.json PDGF receptor signalling pathway|PDGF receptor signaling pathway|PDGFR signaling pathway http://purl.obolibrary.org/obo/GO_0048008 GO:0048007 biolink:BiologicalProcess antigen processing and presentation, exogenous lipid antigen via MHC class Ib The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. go-plus.json antigen presentation, exogenous peptide antigen|exogenous lipid antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0048007 GO:0048006 biolink:BiologicalProcess antigen processing and presentation, endogenous lipid antigen via MHC class Ib The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. go-plus.json endogenous lipid antigen processing and presentation via MHC class Ib|antigen presentation, endogenous lipid antigen http://purl.obolibrary.org/obo/GO_0048006 GO:0000020 biolink:BiologicalProcess obsolete negative regulation of recombination within rDNA repeats OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. go-plus.json negative regulation of recombination within rDNA repeats http://purl.obolibrary.org/obo/GO_0000020 GO:0048005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048005 GO:0048004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048004 GO:0048003 biolink:BiologicalProcess antigen processing and presentation of lipid antigen via MHC class Ib The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. go-plus.json antigen presentation, lipid antigen|lipid antigen processing and presentation via MHC class Ib http://purl.obolibrary.org/obo/GO_0048003 PR:000001370 biolink:Protein interleukin-13 A protein that is a translation product of the human IL13 gene or a 1:1 ortholog thereof. Interleukin-13 is a pleiotropic cytokine which may be important in the regulation of the inflammatory and immune responses. It inhibits inflammatory cytokine production and synergises with IL-2 in regulating interferon-gamma synthesis. The sequences of IL-4 and IL-13 are distantly related. go-plus.json NC30|IL-13|T-cell activation protein P600|IL13 http://purl.obolibrary.org/obo/PR_000001370 CHEBI:133793 biolink:ChemicalSubstance prostaglandin G1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_133793 CHEBI:133796 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,15E,17S)-17-hydroperoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133796 chebi_ph7_3 CHEBI:133795 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,15E,17S,19Z)-17-hydroperoxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133795 chebi_ph7_3 PR:000001366 biolink:Protein interleukin-11 A protein that is a translation product of the human IL11 gene or a 1:1 ortholog thereof. go-plus.json IL11|adipogenesis inhibitory factor|AGIF|IL-11|oprelvekin http://purl.obolibrary.org/obo/PR_000001366 CHEBI:133798 biolink:ChemicalSubstance (7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133798 chebi_ph7_3 CHEBI:133797 biolink:ChemicalSubstance (7Z,10Z,13Z,15E,19Z)-17-hydroperoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133797 chebi_ph7_3 PR:000001368 biolink:Protein interleukin-12 subunit alpha A protein that is a translation product of the human IL12A gene or a 1:1 ortholog thereof. It associates with interleukin-12 subunit beta to form the interleukin-23. Interleukin-12 subunit alpha associates with interleukin-27 subunit beta to form the interleukin-35. go-plus.json IL-12 subunit p35|NKSF1|cytotoxic lymphocyte maturation factor 35 kDa subunit|IL12A|IL-12A|NK cell stimulatory factor chain 1|CLMF p35 http://purl.obolibrary.org/obo/PR_000001368 CHEBI:133799 biolink:ChemicalSubstance (4Z,7Z,10Z,12E,16Z)-14-hydroperoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133799 chebi_ph7_3 CHEBI:143129 biolink:ChemicalSubstance primary fatty amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_143129 chebi_ph7_3 PR:000001369 biolink:Protein interleukin-12 subunit beta A protein that is a translation product of the human IL12B gene or a 1:1 ortholog thereof. Interleukin-12 subunit beta associates with interleukin-12 subunit alpha or interleukin-23 subunit alpha to form the interleukin-23. go-plus.json NKSF2|IL12B|IL-12 subunit p40|cytotoxic lymphocyte maturation factor 40 kDa subunit|IL-12B|NK cell stimulatory factor chain 2|CLMF p40 http://purl.obolibrary.org/obo/PR_000001369 CHEBI:157766 biolink:ChemicalSubstance 2-hydroxy-fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_157766 chebi_ph7_3 GO:0000029 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000029 CHEBI:133790 biolink:ChemicalSubstance linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133790 CHEBI:157763 biolink:ChemicalSubstance polyprenol phosphate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_157763 chebi_ph7_3 CHEBI:133792 biolink:ChemicalSubstance erythronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133792 CHEBI:133791 biolink:ChemicalSubstance 2-hydroxybutyrates go-plus.json http://purl.obolibrary.org/obo/CHEBI_133791 NCBITaxon:2182 biolink:OrganismalEntity Methanococcales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2182 GO:0048013 biolink:BiologicalProcess ephrin receptor signaling pathway The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin. go-plus.json Eph receptor signalling pathway|Eph receptor signaling pathway http://purl.obolibrary.org/obo/GO_0048013 GO:0000035 biolink:MolecularActivity acyl binding Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid. go-plus.json acyl-CoA or acyl binding http://purl.obolibrary.org/obo/GO_0000035 GO:0000034 biolink:MolecularActivity adenine deaminase activity Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3. RHEA:23688|EC:3.5.4.2|MetaCyc:ADENINE-DEAMINASE-RXN go-plus.json adenine aminohydrolase activity|adenase activity|ADase activity|adenine aminase activity http://purl.obolibrary.org/obo/GO_0000034 GO:0048012 biolink:BiologicalProcess hepatocyte growth factor receptor signaling pathway The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands. go-plus.json Met signaling pathway|HGF receptor signaling pathway|HGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0048012 GO:0048011 biolink:BiologicalProcess neurotrophin TRK receptor signaling pathway A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json tropomyosin-receptor-kinase signaling|TrkB signaling pathway|TrkA signaling pathway|TrkC signaling pathway http://purl.obolibrary.org/obo/GO_0048011 GO:0000033 biolink:MolecularActivity alpha-1,3-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage. Reactome:R-HSA-446208|Reactome:R-HSA-4720473|Reactome:R-HSA-4549368|Reactome:R-HSA-446188 go-plus.json http://purl.obolibrary.org/obo/GO_0000033 GO:0000032 biolink:BiologicalProcess cell wall mannoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues. go-plus.json cell wall mannoprotein formation|cell wall mannoprotein biosynthesis|cell wall mannoprotein anabolism|cell wall mannoprotein synthesis http://purl.obolibrary.org/obo/GO_0000032 GO:0048010 biolink:BiologicalProcess vascular endothelial growth factor receptor signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json VEGFR signaling pathway|VEGF receptor signalling pathway|VEGF receptor signaling pathway http://purl.obolibrary.org/obo/GO_0048010 GO:0000039 biolink:MolecularActivity obsolete plasma membrane long-chain fatty acid transporter OBSOLETE. (Was not defined before being made obsolete). go-plus.json plasma membrane long-chain fatty acid transporter http://purl.obolibrary.org/obo/GO_0000039 GO:0000038 biolink:BiologicalProcess very long-chain fatty acid metabolic process The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22. go-plus.json very-long-chain fatty acid metabolism|very long chain fatty acid metabolic process|very-long-chain fatty acid metabolic process http://purl.obolibrary.org/obo/GO_0000038 CHEBI:87391 biolink:ChemicalSubstance N-icosanoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87391 chebi_ph7_3 GO:0000037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000037 GO:0000036 biolink:MolecularActivity acyl carrier activity Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis. go-plus.json ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process http://purl.obolibrary.org/obo/GO_0000036 CHEBI:157759 biolink:ChemicalSubstance glycosylmonoacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_157759 chebi_ph7_3 GO:0048019 biolink:MolecularActivity receptor antagonist activity The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor. go-plus.json receptor ligand activity http://purl.obolibrary.org/obo/GO_0048019 GO:0048018 biolink:MolecularActivity receptor ligand activity The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands). go-plus.json receptor agonist activity|signaling molecule|signaling receptor ligand activity|vitamin D receptor activator activity http://purl.obolibrary.org/obo/GO_0048018 goslim_drosophila|goslim_chembl GO:0048017 biolink:BiologicalProcess inositol lipid-mediated signaling A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids. go-plus.json inositol lipid-mediated signal transduction|inositol lipid-mediated signalling|inositol phospholipid-mediated signaling http://purl.obolibrary.org/obo/GO_0048017 GO:0000031 biolink:MolecularActivity mannosylphosphate transferase activity Catalysis of the transfer of a mannosylphosphate group from one compound to another. go-plus.json http://purl.obolibrary.org/obo/GO_0000031 GO:0000030 biolink:MolecularActivity mannosyltransferase activity Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid. Reactome:R-HSA-162797|Reactome:R-HSA-162830|Reactome:R-HSA-446198|Reactome:R-HSA-4720497 go-plus.json http://purl.obolibrary.org/obo/GO_0000030 GO:0048016 biolink:BiologicalProcess inositol phosphate-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6). go-plus.json inositol phosphate-mediated signalling http://purl.obolibrary.org/obo/GO_0048016 GO:0048015 biolink:BiologicalProcess phosphatidylinositol-mediated signaling A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. go-plus.json inositol phospholipid-mediated signaling|phosphatidylinositol-mediated signalling|phosphatidylinositol-mediated signal transduction|phosphoinositide-mediated signalling|phosphoinositide-mediated signaling http://purl.obolibrary.org/obo/GO_0048015 PR:000001382 biolink:Protein interleukin-21 A protein that is a translation product of the human IL21 gene or a 1:1 ortholog thereof. go-plus.json IL-21|Za11|IL21 http://purl.obolibrary.org/obo/PR_000001382 CHEBI:167148 biolink:ChemicalSubstance 1-linoleoyl-2-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_167148 GO:0048014 biolink:BiologicalProcess Tie signaling pathway The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin). go-plus.json Tie receptor signaling pathway|angiopoietin-Tie signaling pathway|Tek receptor signaling|Tie receptor signalling pathway|angiopoietin/Tie signaling pathway http://purl.obolibrary.org/obo/GO_0048014 PR:000001373 biolink:Protein interleukin-15 A protein that is a translation product of the human IL15 gene or a 1:1 ortholog thereof. go-plus.json IL-15|IL15 http://purl.obolibrary.org/obo/PR_000001373 CHEBI:157750 biolink:ChemicalSubstance heparan sulfate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_157750 chebi_ph7_3 NCBITaxon:2190 biolink:OrganismalEntity Methanocaldococcus jannaschii go-plus.json Methanococcus jannaschii http://purl.obolibrary.org/obo/NCBITaxon_2190 PR:000001374 biolink:Protein interleukin-16 A protein that is a translation product of the human IL16 gene or a 1:1 ortholog thereof. go-plus.json IL16 http://purl.obolibrary.org/obo/PR_000001374 PR:000001376 biolink:Protein interleukin-18 A protein that is a translation product of the human IL18 gene or a 1:1 ortholog thereof. go-plus.json IL-18|IL-1 gamma|IL18|interferon gamma-inducing factor|interleukin-1 gamma|IFN-gamma-inducing factor|IL1F4|IGIF|iboctadekin http://purl.obolibrary.org/obo/PR_000001376 PR:000001379 biolink:Protein interleukin-2 A protein that is a translation product of the human IL2 gene or a 1:1 ortholog thereof. Interleukin-2 has a dual role in maintaining tolerance and contributing to immunity. go-plus.json IL2|TCGF|IL-2|T-cell growth factor|aldesleukin http://purl.obolibrary.org/obo/PR_000001379 CHEBI:157758 biolink:ChemicalSubstance 1-acyl-2-hydroxy-sn-glycero-3-phospho-(N-acyl)-serine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_157758 chebi_ph7_3 CHEBI:157757 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-(N-acyl)-serine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_157757 chebi_ph7_3 SO:0000842 biolink:SequenceFeature gene_component_region A region of a gene that has a specific function. go-plus.json gene component region http://purl.obolibrary.org/obo/SO_0000842 SOFA GO:0048024 biolink:BiologicalProcess regulation of mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism. go-plus.json regulation of pre-mRNA splicing|regulation of nuclear mRNA splicing via U2-type spliceosome|regulation of nuclear mRNA splicing, via spliceosome http://purl.obolibrary.org/obo/GO_0048024 GO:0000002 biolink:BiologicalProcess mitochondrial genome maintenance The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000002 GO:0000001 biolink:BiologicalProcess mitochondrion inheritance The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. go-plus.json mitochondrial inheritance http://purl.obolibrary.org/obo/GO_0000001 GO:0048023 biolink:BiologicalProcess positive regulation of melanin biosynthetic process Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin. go-plus.json upregulation of melanin biosynthetic process|stimulation of melanin biosynthetic process|activation of melanin biosynthetic process|up-regulation of melanin biosynthetic process|positive regulation of melanin anabolism|positive regulation of melanin biosynthesis|positive regulation of melanin synthesis|up regulation of melanin biosynthetic process|positive regulation of melanin formation http://purl.obolibrary.org/obo/GO_0048023 GO:0048022 biolink:BiologicalProcess negative regulation of melanin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin. go-plus.json negative regulation of melanin formation|down regulation of melanin biosynthetic process|inhibition of melanin biosynthetic process|negative regulation of melanin biosynthesis|down-regulation of melanin biosynthetic process|negative regulation of melanin anabolism|negative regulation of melanin synthesis|downregulation of melanin biosynthetic process http://purl.obolibrary.org/obo/GO_0048022 GO:0048021 biolink:BiologicalProcess regulation of melanin biosynthetic process Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin. go-plus.json regulation of melanin biosynthesis|regulation of melanin anabolism|regulation of melanin synthesis|regulation of melanin formation http://purl.obolibrary.org/obo/GO_0048021 GO:0000006 biolink:MolecularActivity high-affinity zinc transmembrane transporter activity Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high-affinity zinc uptake transmembrane transporter activity|high affinity zinc uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0000006 GO:0048020 biolink:MolecularActivity CCR chemokine receptor binding Binding to a CCR chemokine receptor. go-plus.json CCR chemokine receptor ligand|beta chemokine receptor ligand|beta chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 GO:0000005 biolink:MolecularActivity obsolete ribosomal chaperone activity OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function. go-plus.json ribosomal chaperone activity http://purl.obolibrary.org/obo/GO_0000005 GO:0000004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000004 GO:0000003 biolink:BiologicalProcess reproduction The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. Wikipedia:Reproduction go-plus.json reproductive physiological process http://purl.obolibrary.org/obo/GO_0000003 goslim_plant|goslim_pir|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_agr GO:0048029 biolink:MolecularActivity monosaccharide binding Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. go-plus.json http://purl.obolibrary.org/obo/GO_0048029 GO:0048028 biolink:MolecularActivity galacturonan binding Binding to a simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins. go-plus.json polygalacturonide binding http://purl.obolibrary.org/obo/GO_0048028 GO:0048027 biolink:MolecularActivity mRNA 5'-UTR binding Binding to an mRNA molecule at its 5' untranslated region. go-plus.json mRNA 5' UTR binding http://purl.obolibrary.org/obo/GO_0048027 GO:0048026 biolink:BiologicalProcess positive regulation of mRNA splicing, via spliceosome Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism. go-plus.json up regulation of nuclear mRNA splicing via U2-type spliceosome|up regulation of nuclear mRNA splicing, via spliceosome|positive regulation of pre-mRNA splicing|positive regulation of nuclear mRNA splicing via U2-type spliceosome|activation of nuclear mRNA splicing via U2-type spliceosome|stimulation of nuclear mRNA splicing via U2-type spliceosome|upregulation of nuclear mRNA splicing, via spliceosome|up-regulation of nuclear mRNA splicing via U2-type spliceosome|positive regulation of nuclear mRNA splicing, via spliceosome|stimulation of nuclear mRNA splicing, via spliceosome|up-regulation of nuclear mRNA splicing, via spliceosome|activation of nuclear mRNA splicing, via spliceosome|upregulation of nuclear mRNA splicing via U2-type spliceosome http://purl.obolibrary.org/obo/GO_0048026 GO:0048025 biolink:BiologicalProcess negative regulation of mRNA splicing, via spliceosome Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. go-plus.json down regulation of nuclear mRNA splicing via U2-type spliceosome|down-regulation of nuclear mRNA splicing, via spliceosome|downregulation of nuclear mRNA splicing via U2-type spliceosome|downregulation of nuclear mRNA splicing, via spliceosome|negative regulation of nuclear mRNA splicing via U2-type spliceosome|negative regulation of pre-mRNA splicing|down-regulation of nuclear mRNA splicing via U2-type spliceosome|down regulation of nuclear mRNA splicing, via spliceosome|negative regulation of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing via U2-type spliceosome http://purl.obolibrary.org/obo/GO_0048025 CHEBI:133772 biolink:ChemicalSubstance (S)-PGJ2-S-glutathione conjugate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133772 chebi_ph7_3 CHEBI:133771 biolink:ChemicalSubstance (R)-PGJ2-S-glutathione conjugate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133771 chebi_ph7_3 CHEBI:133773 biolink:ChemicalSubstance pimelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133773 CHEBI:133775 biolink:ChemicalSubstance dimethylargininium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133775 CHEBI:133778 biolink:ChemicalSubstance 1alpha-hydroxyandrost-4-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_133778 chebi_ph7_3 GO:0000009 biolink:MolecularActivity alpha-1,6-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage. EC:2.4.1.232|Reactome:R-HSA-449718 go-plus.json 1,6-alpha-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0000009 GO:0000008 biolink:MolecularActivity obsolete thioredoxin OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol. go-plus.json thioredoxin http://purl.obolibrary.org/obo/GO_0000008 GO:0000007 biolink:MolecularActivity low-affinity zinc ion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json http://purl.obolibrary.org/obo/GO_0000007 CHEBI:157740 biolink:ChemicalSubstance N-(fatty acyl)-dopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_157740 chebi_ph7_3 GO:0048035 biolink:BiologicalProcess heme o catabolic process The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. go-plus.json heme o breakdown|haem o catabolism|haem o catabolic process|heme o catabolism|heme o degradation http://purl.obolibrary.org/obo/GO_0048035 GO:0000013 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000013 GO:0048034 biolink:BiologicalProcess heme O biosynthetic process The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. go-plus.json heme O biosynthesis|heme O anabolism|haem O biosynthesis|haem O biosynthetic process|heme O synthesis|heme O formation http://purl.obolibrary.org/obo/GO_0048034 GO:0000012 biolink:BiologicalProcess single strand break repair The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair. go-plus.json http://purl.obolibrary.org/obo/GO_0000012 GO:0048033 biolink:BiologicalProcess heme o metabolic process The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. go-plus.json heme o metabolism|haem o metabolism|haem o metabolic process http://purl.obolibrary.org/obo/GO_0048033 CHEBI:167166 biolink:ChemicalSubstance 3-oxocholestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_167166 GO:0000011 biolink:BiologicalProcess vacuole inheritance The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0000011 SO:0000871 biolink:SequenceFeature polyadenylated_mRNA An mRNA that is polyadenylated. go-plus.json polyadenylated mRNA http://purl.obolibrary.org/obo/SO_0000871 GO:0048032 biolink:MolecularActivity galacturonate binding Binding to a galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. go-plus.json galacturonic acid binding http://purl.obolibrary.org/obo/GO_0048032 GO:0000010 biolink:MolecularActivity trans-hexaprenyltranstransferase activity Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate. RHEA:20836 go-plus.json http://purl.obolibrary.org/obo/GO_0000010 GO:0048031 biolink:MolecularActivity trisaccharide binding Binding to a trisaccharide. Trisaccharides are sugars composed of three monosaccharide units. go-plus.json http://purl.obolibrary.org/obo/GO_0048031 GO:0000017 biolink:BiologicalProcess alpha-glucoside transport The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration. go-plus.json http://purl.obolibrary.org/obo/GO_0000017 GO:0048030 biolink:MolecularActivity disaccharide binding Binding to a disaccharide. Disaccharides are sugars composed of two monosaccharide units. go-plus.json http://purl.obolibrary.org/obo/GO_0048030 GO:0000016 biolink:MolecularActivity lactase activity Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose. Reactome:R-HSA-189062|EC:3.2.1.108|RHEA:10076|Reactome:R-HSA-5658001|MetaCyc:LACTASE-RXN go-plus.json lactose galactohydrolase activity|lactase-phlorizin hydrolase activity http://purl.obolibrary.org/obo/GO_0000016 GO:0000015 biolink:CellularComponent phosphopyruvate hydratase complex A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water. go-plus.json enolase complex http://purl.obolibrary.org/obo/GO_0000015 goslim_metagenomics GO:0000014 biolink:MolecularActivity single-stranded DNA endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks. go-plus.json ssDNA-specific endodeoxyribonuclease activity|single-stranded DNA specific endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0000014 GO:0048039 biolink:MolecularActivity ubiquinone binding Binding to ubiquinone, a quinone derivative with a tail of isoprene units. go-plus.json coenzyme Q6 binding|coenzyme Q binding http://purl.obolibrary.org/obo/GO_0048039 GO:0048038 biolink:MolecularActivity quinone binding Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0048038 GO:0048037 biolink:MolecularActivity obsolete cofactor binding OBSOLETE. Binding to a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0048037 GO:0048036 biolink:BiologicalProcess central complex development The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli. go-plus.json central body development http://purl.obolibrary.org/obo/GO_0048036 GO:0000019 biolink:BiologicalProcess regulation of mitotic recombination Any process that modulates the frequency, rate or extent of DNA recombination during mitosis. go-plus.json regulation of recombination within rDNA repeats http://purl.obolibrary.org/obo/GO_0000019 GO:0000018 biolink:BiologicalProcess regulation of DNA recombination Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. go-plus.json http://purl.obolibrary.org/obo/GO_0000018 SO:0000862 biolink:SequenceFeature capped_mRNA An mRNA that is capped. go-plus.json capped mRNA http://purl.obolibrary.org/obo/SO_0000862 GO:0048046 biolink:CellularComponent apoplast The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. Wikipedia:Apoplast go-plus.json http://purl.obolibrary.org/obo/GO_0048046 GO:0048045 biolink:MolecularActivity trans-pentaprenyltranstransferase activity Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate. KEGG_REACTION:R05613|RHEA:22632 go-plus.json all-trans-hexaprenyl-diphosphate synthase activity|hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity|all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity http://purl.obolibrary.org/obo/GO_0048045 CHEBI:7091 biolink:ChemicalSubstance N-(5-phospho-beta-D-ribosyl)anthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7091 GO:0048044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048044 GO:0048043 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048043 GO:0048042 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048042 GO:0048041 biolink:BiologicalProcess focal adhesion assembly The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. go-plus.json adhesion plaque assembly|focal adhesion formation http://purl.obolibrary.org/obo/GO_0048041 GO:0048040 biolink:MolecularActivity UDP-glucuronate decarboxylase activity Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose. EC:4.1.1.35|KEGG_REACTION:R01384|MetaCyc:UDP-GLUCURONATE-DECARBOXYLASE-RXN|RHEA:23916 go-plus.json uridine-diphosphoglucuronate decarboxylase activity|UDP-D-glucuronate carboxy-lyase activity|UDPglucuronate decarboxylase activity|UDP-glucuronic acid decarboxylase activity|UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming) http://purl.obolibrary.org/obo/GO_0048040 GO:1903209 biolink:BiologicalProcess positive regulation of oxidative stress-induced cell death Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death. go-plus.json enhancement of oxidative stress-induced cell death|up regulation of cell death in response to oxidative stress|upregulation of cell death in response to oxidative stress|positive regulation of cell death in response to oxidative stress|activation of cell death in response to oxidative stress|up-regulation of cell death in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903209 CHEBI:38390 biolink:ChemicalSubstance 9,11,15-octadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38390 chebi_ph7_3 GO:1903208 biolink:BiologicalProcess negative regulation of hydrogen peroxide-induced neuron death Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death. go-plus.json down regulation of neuron death in response to H2O2|inhibition of neuron death in response to H2O2|protection against hydrogen peroxide-induced neuron death|down-regulation of hydrogen peroxide-induced neuron death|downregulation of neuronal cell death in response to hydrogen peroxide|down-regulation of neuron death in response to hydrogen peroxide|down regulation of neuronal cell death in response to hydrogen peroxide|negative regulation of neuron death in response to hydrogen peroxide|inhibition of neuronal cell death in response to hydrogen peroxide|downregulation of hydrogen peroxide-induced neuron death|neuroprotection against H2O2-induced cell death|inhibition of neuron death in response to hydrogen peroxide|down regulation of hydrogen peroxide-induced neuron death|inhibition of hydrogen peroxide-induced neuron death|negative regulation of neuron death in response to H2O2|down-regulation of neuron death in response to H2O2|neuroprotection against hydrogen peroxide|protection against H2O2-induced neuron death|down regulation of neuron death in response to hydrogen peroxide|downregulation of neuron death in response to H2O2|down-regulation of neuronal cell death in response to hydrogen peroxide|negative regulation of neuronal cell death in response to hydrogen peroxide|downregulation of neuron death in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_1903208 GO:1903207 biolink:BiologicalProcess regulation of hydrogen peroxide-induced neuron death Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced neuron death. go-plus.json regulation of neuronal cell death in response to hydrogen peroxide|regulation of neuron death in response to H2O2|regulation of neuron death in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_1903207 GO:1903206 biolink:BiologicalProcess negative regulation of hydrogen peroxide-induced cell death Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death. go-plus.json downregulation of hydrogen peroxide-mediated cell death|negative regulation of cell death in response to H2O2|down-regulation of cell death in response to H2O2|protection against H2O2-induced cell death|down regulation of cell death in response to hydrogen peroxide|negative regulation of hydrogen peroxide-mediated cell death|down-regulation of hydrogen peroxide-mediated cell death|downregulation of cell death in response to H2O2|downregulation of cell death in response to hydrogen peroxide|down regulation of cell death in response to H2O2|inhibition of cell death in response to H2O2|protection against hydrogen peroxide-induced cell death|inhibition of hydrogen peroxide-mediated cell death|down-regulation of cell death in response to hydrogen peroxide|negative regulation of cell death in response to hydrogen peroxide|inhibition of cell death in response to hydrogen peroxide|down regulation of hydrogen peroxide-mediated cell death http://purl.obolibrary.org/obo/GO_1903206 GO:1903205 biolink:BiologicalProcess regulation of hydrogen peroxide-induced cell death Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death. go-plus.json regulation of cell death in response to hydrogen peroxide|regulation of cell death in response to H2O2|protection against hydrogen peroxide-mediated cell death|regulation of hydrogen peroxide-mediated cell death http://purl.obolibrary.org/obo/GO_1903205 GO:1903204 biolink:BiologicalProcess negative regulation of oxidative stress-induced neuron death Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death. go-plus.json down regulation of oxidative stress-induced neuron death|downregulation of oxidative stress-induced neuron death|down regulation of neuronal cell death in response to oxidative stress|neuronal protection under oxidative stress|down-regulation of neuron death in response to oxidative stress|neuroprotection against oxidative stress|downregulation of neuronal cell death in response to oxidative stress|down-regulation of oxidative stress-induced neuron death|downregulation of neuron death in response to oxidative stress|inhibition of oxidative stress-induced neuron death|negative regulation of neuronal cell death in response to oxidative stress|down-regulation of neuronal cell death in response to oxidative stress|down regulation of neuron death in response to oxidative stress|inhibition of neuron death in response to oxidative stress|inhibition of neuronal cell death in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903204 GO:1903203 biolink:BiologicalProcess regulation of oxidative stress-induced neuron death Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death. go-plus.json regulation of neuronal cell death in response to oxidative stress|regulation of neuron death in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903203 GO:1903202 biolink:BiologicalProcess negative regulation of oxidative stress-induced cell death Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death. go-plus.json downregulation of cell death in response to oxidative stress|down regulation of cell death in response to oxidative stress|inhibition of cell death in response to oxidative stress|protection against oxidative stress-induced cell death|down-regulation of cell death in response to oxidative stress|negative regulation of cell death in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903202 GO:0048049 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048049 GO:1903201 biolink:BiologicalProcess regulation of oxidative stress-induced cell death Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death. go-plus.json regulation of cell death in response to oxidative stress http://purl.obolibrary.org/obo/GO_1903201 GO:0048048 biolink:BiologicalProcess embryonic eye morphogenesis The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048048 GO:1903200 biolink:BiologicalProcess positive regulation of L-dopa decarboxylase activity Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity. go-plus.json up-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|upregulation of DOPA decarboxylase activity|upregulation of L-dopa decarboxylase activity|upregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|upregulation of DDC activity|up regulation of DOPA decarboxylase activity|up regulation of L-dopa decarboxylase activity|activation of DOPA decarboxylase activity|activation of DDC activity|positive regulation of DOPA decarboxylase activity|activation of L-dopa decarboxylase activity|up-regulation of DDC activity|up regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|activation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|positive regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|positive regulation of DDC activity|up-regulation of DOPA decarboxylase activity|up-regulation of L-dopa decarboxylase activity|up regulation of DDC activity http://purl.obolibrary.org/obo/GO_1903200 GO:0048047 biolink:BiologicalProcess mating behavior, sex discrimination The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner. go-plus.json mating behaviour, sex discrimination http://purl.obolibrary.org/obo/GO_0048047 GO:1903210 biolink:BiologicalProcess glomerular visceral epithelial cell apoptotic process Any apoptotic process in a glomerular visceral epithelial cell. go-plus.json glomerular podocyte apoptosis|glomerular podocyte apoptotic process|podocyte apoptosis|podocyte apoptotic process|glomerular visceral epithelial cell apoptosis http://purl.obolibrary.org/obo/GO_1903210 CHEBI:133752 biolink:ChemicalSubstance epsilon-(gamma-glutamyl)lysine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133752 chebi_ph7_3 CHEBI:38382 biolink:ChemicalSubstance 9,11,13-octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38382 CHEBI:38387 biolink:ChemicalSubstance 9,11,15-octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38387 GO:0048057 biolink:BiologicalProcess R3/R4 development The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048057 GO:0048056 biolink:BiologicalProcess R3/R4 cell differentiation The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048056 GO:0048055 biolink:BiologicalProcess R2/R5 development The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048055 GO:0048054 biolink:BiologicalProcess R2/R5 cell differentiation The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048054 GO:0048053 biolink:BiologicalProcess R1/R6 development The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048053 GO:0048052 biolink:BiologicalProcess R1/R6 cell differentiation The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0048052 GO:0048051 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048051 GO:1903219 biolink:BiologicalProcess negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity. go-plus.json downregulation of 'malic' enzyme|downregulation of NADP-linked decarboxylating malic enzyme|down-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of NADP-specific malic enzyme|down regulation of NADP-specific malate dehydrogenase activity|down-regulation of NADP-malic enzyme activity|negative regulation of NADP-malic enzyme activity|down regulation of 'malic' enzyme|down regulation of NADP-linked decarboxylating malic enzyme|downregulation of NADP-specific malate dehydrogenase activity|inhibition of malate dehydrogenase (decarboxylating) (NADP+) activity|down-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down-regulation of malate dehydrogenase (NADP, decarboxylating)|negative regulation of malate dehydrogenase (NADP, decarboxylating)|negative regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of L-malate:NADP oxidoreductase activity|inhibition of 'malic' enzyme|inhibition of NADP-linked decarboxylating malic enzyme|downregulation of NADP-malic enzyme activity|negative regulation of NADP-specific malic enzyme|down-regulation of NADP-specific malic enzyme|downregulation of L-malate:NADP oxidoreductase activity|down-regulation of NADP-specific malate dehydrogenase activity|negative regulation of NADP-specific malate dehydrogenase activity|negative regulation of malate dehydrogenase (decarboxylating, NADP)|down-regulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of NADP-malic enzyme activity|inhibition of NADP-malic enzyme activity|downregulation of malate dehydrogenase (NADP, decarboxylating)|downregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of NADP-specific malate dehydrogenase activity|downregulation of NADP-specific malic enzyme|down-regulation of 'malic' enzyme|down regulation of malate dehydrogenase (NADP, decarboxylating)|down regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|negative regulation of 'malic' enzyme|downregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down-regulation of NADP-linked decarboxylating malic enzyme|negative regulation of L-malate:NADP oxidoreductase activity|negative regulation of NADP-linked decarboxylating malic enzyme|inhibition of malate dehydrogenase (NADP, decarboxylating)|down-regulation of L-malate:NADP oxidoreductase activity|downregulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of NADP-specific malic enzyme|down regulation of malate dehydrogenase (decarboxylating, NADP)|inhibition of L-malate:NADP oxidoreductase activity|inhibition of malate dehydrogenase (decarboxylating, NADP) http://purl.obolibrary.org/obo/GO_1903219 GO:0048050 biolink:BiologicalProcess post-embryonic eye morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight. go-plus.json http://purl.obolibrary.org/obo/GO_0048050 CHEBI:167183 biolink:ChemicalSubstance piscicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_167183 GO:1903218 biolink:BiologicalProcess regulation of malate dehydrogenase (decarboxylating) (NADP+) activity Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity. go-plus.json regulation of 'malic' enzyme|regulation of NADP-linked decarboxylating malic enzyme|regulation of NADP-specific malate dehydrogenase activity|regulation of L-malate:NADP oxidoreductase activity|regulation of NADP-malic enzyme activity|regulation of malate dehydrogenase (NADP, decarboxylating)|regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|regulation of NADP-specific malic enzyme|regulation of malate dehydrogenase (decarboxylating, NADP) http://purl.obolibrary.org/obo/GO_1903218 CHEBI:133769 biolink:ChemicalSubstance (S)-PGA2-S-glutathione conjugate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133769 chebi_ph7_3 GO:1903217 biolink:BiologicalProcess negative regulation of protein processing involved in protein targeting to mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion. go-plus.json inhibition of protein processing involved in protein targeting to mitochondrion|inhibition of mitochondrial protein processing during import|down regulation of protein processing involved in protein targeting to mitochondrion|downregulation of protein processing involved in protein targeting to mitochondrion|negative regulation of mitochondrial protein processing during import|down-regulation of mitochondrial protein processing during import|down-regulation of protein processing involved in protein targeting to mitochondrion|downregulation of mitochondrial protein processing during import|down regulation of mitochondrial protein processing during import http://purl.obolibrary.org/obo/GO_1903217 CHEBI:133768 biolink:ChemicalSubstance (R)-PGA2-S-glutathione conjugate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133768 chebi_ph7_3 GO:1903216 biolink:BiologicalProcess regulation of protein processing involved in protein targeting to mitochondrion Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion. go-plus.json regulation of mitochondrial processing|regulation of mitochondrial protein processing during import http://purl.obolibrary.org/obo/GO_1903216 GO:1903215 biolink:BiologicalProcess negative regulation of protein targeting to mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion. go-plus.json down regulation of mitochondrial translocation|down-regulation of mitochondrial protein import|negative regulation of mitochondrial protein import|downregulation of mitochondrial translocation|inhibition of protein-mitochondrial targeting|down regulation of protein import into mitochondrion|down regulation of protein targeting to mitochondria|downregulation of protein import into mitochondrion|downregulation of mitochondrial protein import|negative regulation of mitochondrial translocation|downregulation of protein targeting to mitochondria|down-regulation of mitochondrial translocation|down-regulation of protein targeting to mitochondrion|down regulation of mitochondrial protein import|down regulation of protein-mitochondrial targeting|down-regulation of protein import into mitochondrion|negative regulation of protein import into mitochondrion|downregulation of protein-mitochondrial targeting|down-regulation of protein targeting to mitochondria|inhibition of mitochondrial protein import|negative regulation of protein targeting to mitochondria|downregulation of protein targeting to mitochondrion|inhibition of mitochondrial translocation|inhibition of protein import into mitochondrion|down regulation of protein targeting to mitochondrion|inhibition of protein targeting to mitochondrion|inhibition of protein targeting to mitochondria|negative regulation of protein-mitochondrial targeting|down-regulation of protein-mitochondrial targeting http://purl.obolibrary.org/obo/GO_1903215 GO:1903214 biolink:BiologicalProcess regulation of protein targeting to mitochondrion Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion. go-plus.json regulation of mitochondrial translocation|regulation of protein import into mitochondrion|regulation of protein targeting to mitochondria|regulation of mitochondrial protein import|regulation of protein-mitochondrial targeting http://purl.obolibrary.org/obo/GO_1903214 GO:1903213 biolink:BiologicalProcess protein localization to subtelomeric heterochromatin A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin. go-plus.json protein localisation in subtelomeric heterochromatin|protein localization in subtelomeric heterochromatin|protein localization to telomeric heterochromatin|protein localisation to telomeric heterochromatin|protein localisation to subtelomeric heterochromatin http://purl.obolibrary.org/obo/GO_1903213 GO:1903212 biolink:BiologicalProcess protein localization to mating-type region heterochromatin A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin. go-plus.json protein localisation to mating-type region heterochromatin|protein localisation in mating-type region heterochromatin|protein localization in mating-type region heterochromatin http://purl.obolibrary.org/obo/GO_1903212 GO:0048059 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048059 GO:1903211 biolink:BiologicalProcess mitotic recombination involved in replication fork processing Any mitotic recombination that is involved in replication fork processing. go-plus.json mitotic recombination involved in replication fork restart|mitotic recombination involved in replication restart|mitotic recombination involved in collapsed replication fork processing|mitotic recombination involved in recovery from replication fork arrest|mitotic recombination involved in recovery from replication fork stalling http://purl.obolibrary.org/obo/GO_1903211 GO:0048058 biolink:BiologicalProcess compound eye corneal lens development The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048058 GO:1903221 biolink:BiologicalProcess regulation of mitotic recombination involved in replication fork processing Any process that modulates the frequency, rate or extent of mitotic recombination involved in replication fork processing. Regulation of mitotic recombination contributes to replication fork processing by preventing recombination between inappropriate homologous sequences. go-plus.json regulation of mitotic recombination involved in recovery from replication fork stalling|regulation of mitotic recombination involved in replication restart|regulation of mitotic recombination involved in collapsed replication fork processing|prevention of genomic instability induced by DNA replication fork arrest|regulation of mitotic recombination involved in replication fork restart|regulation of mitotic recombination involved in recovery from replication fork arrest http://purl.obolibrary.org/obo/GO_1903221 GO:1903220 biolink:BiologicalProcess positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity. go-plus.json up-regulation of NADP-specific malate dehydrogenase activity|up regulation of malate dehydrogenase (decarboxylating, NADP)|activation of 'malic' enzyme|activation of NADP-linked decarboxylating malic enzyme|upregulation of malate dehydrogenase (NADP, decarboxylating)|upregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|positive regulation of 'malic' enzyme|up regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of NADP-malic enzyme activity|up-regulation of NADP-malic enzyme activity|positive regulation of NADP-linked decarboxylating malic enzyme|up regulation of 'malic' enzyme|upregulation of NADP-specific malic enzyme|up regulation of NADP-linked decarboxylating malic enzyme|up-regulation of L-malate:NADP oxidoreductase activity|upregulation of NADP-specific malate dehydrogenase activity|upregulation of malate dehydrogenase (decarboxylating, NADP)|activation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|up-regulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of NADP-specific malic enzyme|upregulation of 'malic' enzyme|positive regulation of NADP-malic enzyme activity|upregulation of L-malate:NADP oxidoreductase activity|upregulation of NADP-linked decarboxylating malic enzyme|up-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|up-regulation of malate dehydrogenase (decarboxylating, NADP)|up regulation of NADP-malic enzyme activity|activation of malate dehydrogenase (decarboxylating, NADP)|up regulation of NADP-specific malate dehydrogenase activity|activation of NADP-specific malate dehydrogenase activity|positive regulation of NADP-specific malate dehydrogenase activity|activation of NADP-specific malic enzyme|positive regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|positive regulation of malate dehydrogenase (NADP, decarboxylating)|up regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|up regulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of 'malic' enzyme|up-regulation of NADP-linked decarboxylating malic enzyme|upregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|positive regulation of NADP-specific malic enzyme|up regulation of L-malate:NADP oxidoreductase activity|activation of L-malate:NADP oxidoreductase activity|up regulation of NADP-specific malic enzyme|upregulation of NADP-malic enzyme activity|positive regulation of L-malate:NADP oxidoreductase activity|positive regulation of malate dehydrogenase (decarboxylating, NADP) http://purl.obolibrary.org/obo/GO_1903220 GO:0048060 biolink:BiologicalProcess negative gravitaxis The directed movement of a motile cell or organism away from the source of gravity. go-plus.json negative taxis in response to gravity|negative gravitactic behavior|negative geotactic behaviour|negative taxis in response to gravitytaxis in response to gravitational stimulus|negative geotactic behavior|negative gravitactic behaviour http://purl.obolibrary.org/obo/GO_0048060 CHEBI:38393 biolink:ChemicalSubstance octadeca-9,11-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38393 chebi_ph7_3 CHEBI:77979 biolink:ChemicalSubstance aclacinomycin T zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77979 chebi_ph7_3 CHEBI:77978 biolink:ChemicalSubstance 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77978 chebi_ph7_3 CHEBI:77977 biolink:ChemicalSubstance noreugenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77977 chebi_ph7_3 CHEBI:77976 biolink:ChemicalSubstance versicolorin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77976 chebi_ph7_3 CHEBI:63330 biolink:ChemicalSubstance sodium-dependent Pi-transporter inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63330 CHEBI:87300 biolink:ChemicalSubstance 2-O-(alpha-D-glucosyl)-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87300 CHEBI:63332 biolink:ChemicalSubstance EC 3.1.3.1 (alkaline phosphatase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63332 CHEBI:63331 biolink:ChemicalSubstance 9(R)-HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63331 CHEBI:87305 biolink:ChemicalSubstance trans-feruloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87305 chebi_ph7_3 CHEBI:63338 biolink:ChemicalSubstance deoxy sugar derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63338 CHEBI:87306 biolink:ChemicalSubstance (7R)-6-deoxy-D-manno-oct-7-ulosuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87306 CHEBI:63339 biolink:ChemicalSubstance deoxy oligosaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63339 CHEBI:77971 biolink:ChemicalSubstance raising agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_77971 CHEBI:77970 biolink:ChemicalSubstance food thickening agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_77970 CHEBI:77975 biolink:ChemicalSubstance (2S,3S)-versiconal hemiacetal acetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77975 chebi_ph7_3 CHEBI:77974 biolink:ChemicalSubstance food packaging gas go-plus.json http://purl.obolibrary.org/obo/CHEBI_77974 CHEBI:77989 biolink:ChemicalSubstance luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)](3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77989 chebi_ph7_3 CHEBI:77988 biolink:ChemicalSubstance methyl aklanonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77988 chebi_ph7_3 CHEBI:77987 biolink:ChemicalSubstance aklanonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77987 chebi_ph7_3 CHEBI:63340 biolink:ChemicalSubstance deoxyhexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63340 CHEBI:63349 biolink:ChemicalSubstance trideoxyhexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63349 CHEBI:63347 biolink:ChemicalSubstance dideoxyhexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63347 CHEBI:63346 biolink:ChemicalSubstance deoxymannose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63346 CHEBI:77982 biolink:ChemicalSubstance tetracenomycin F2(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77982 chebi_ph7_3 PR:000001315 biolink:Protein frizzled-like G-protein coupled receptor A G-protein coupled receptor with core architecture consisting of an Fz domain (Pfam:PF01392), also known as Frizzled CRD (cysteine rich domain), followed by a Frizzled/Smoothened family membrane region (Pfam:PF01534), which includes 7 transmembrane helices, and a cytoplasmic domain containing the motif Lys-Thr-x-x-x-Trp. They generally function as cell-surface receptors for Wnts. go-plus.json class F G-protein coupled receptor|fam:frizzled http://purl.obolibrary.org/obo/PR_000001315 CHEBI:77981 biolink:ChemicalSubstance vancomycin aglycone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77981 chebi_ph7_3 CHEBI:77980 biolink:ChemicalSubstance aclacinomycin A zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77980 chebi_ph7_3 PR:000001317 biolink:Protein interleukin-7 A protein that is a translation product of the human IL7 gene or a 1:1 ortholog thereof. go-plus.json IL7|IL-7 http://purl.obolibrary.org/obo/PR_000001317 CHEBI:77985 biolink:ChemicalSubstance aclacinomycin Y zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77985 chebi_ph7_3 CHEBI:77984 biolink:ChemicalSubstance quercetin 3,3',7-trissulfate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77984 chebi_ph7_3 CHEBI:77983 biolink:ChemicalSubstance 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate(13-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77983 chebi_ph7_3 CHEBI:77999 biolink:ChemicalSubstance 1(3)-O-(alk-1-enyl)-2-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77999 chebi_ph7_3 CHEBI:77998 biolink:ChemicalSubstance 1(3)-O-(alk-1-enyl)-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77998 chebi_ph7_3 CHEBI:63352 biolink:ChemicalSubstance deoxyaldohexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63352 CHEBI:63351 biolink:ChemicalSubstance deoxyketopentose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63351 CHEBI:63350 biolink:ChemicalSubstance deoxyketohexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63350 CHEBI:63355 biolink:ChemicalSubstance deoxypentose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63355 CHEBI:63353 biolink:ChemicalSubstance disaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63353 CHEBI:77992 biolink:ChemicalSubstance calycosin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77992 chebi_ph7_3 CHEBI:77991 biolink:ChemicalSubstance aclacinomycin N zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77991 chebi_ph7_3 CHEBI:77990 biolink:ChemicalSubstance tetracenomycin D3(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77990 chebi_ph7_3 CHEBI:77997 biolink:ChemicalSubstance 1(3)-O-alkylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77997 chebi_ph7_3 CHEBI:77996 biolink:ChemicalSubstance N-oleoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77996 chebi_ph7_3 CHEBI:77994 biolink:ChemicalSubstance aklaviketone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77994 chebi_ph7_3 CHEBI:143197 biolink:ChemicalSubstance culmorin go-plus.json http://purl.obolibrary.org/obo/CHEBI_143197 chebi_ph7_3 CHEBI:63361 biolink:ChemicalSubstance glycosylglucose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63361 CHEBI:63360 biolink:ChemicalSubstance glycosylgalactose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63360 CHEBI:63367 biolink:ChemicalSubstance monosaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63367 CHEBI:87313 biolink:ChemicalSubstance 8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87313 CHEBI:63369 biolink:ChemicalSubstance D-aldose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63369 CHEBI:63368 biolink:ChemicalSubstance aldose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63368 GO:0000089 biolink:BiologicalProcess mitotic metaphase The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0000089 gocheck_do_not_annotate GO:0000088 biolink:BiologicalProcess mitotic prophase The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0000088 gocheck_do_not_annotate GO:0000087 biolink:BiologicalProcess mitotic M phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle. go-plus.json M-phase of mitotic cell cycle|M phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000087 gocheck_do_not_annotate GO:0000082 biolink:BiologicalProcess G1/S transition of mitotic cell cycle The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. go-plus.json http://purl.obolibrary.org/obo/GO_0000082 CHEBI:63373 biolink:ChemicalSubstance aldopentose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63373 GO:0000081 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000081 GO:0000080 biolink:BiologicalProcess mitotic G1 phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis. go-plus.json G1 phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000080 gocheck_do_not_annotate GO:0000086 biolink:BiologicalProcess G2/M transition of mitotic cell cycle The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. go-plus.json mitotic G2/M transition http://purl.obolibrary.org/obo/GO_0000086 CHEBI:63378 biolink:ChemicalSubstance anhydro sugar derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63378 GO:0000085 biolink:BiologicalProcess mitotic G2 phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis. go-plus.json G2 phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000085 gocheck_do_not_annotate GO:0000084 biolink:BiologicalProcess mitotic S phase The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle. go-plus.json S phase of mitotic cell cycle|S-phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000084 gocheck_do_not_annotate GO:0000083 biolink:BiologicalProcess regulation of transcription involved in G1/S transition of mitotic cell cycle Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0000083 CHEBI:63379 biolink:ChemicalSubstance anhydrohexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63379 PR:000001348 biolink:Protein erythrocyte membrane protein Rh A protein that is a stand alone version of the Ammonium Transporter Family domain in vertebrates. This protein is related to the ammonium transporters in fungi and bacteria. In mammals, this protein defines the Rh blood group antigens. go-plus.json http://purl.obolibrary.org/obo/PR_000001348 PR:000001349 biolink:Protein fibroblast growth factor receptor A protein with an extracellular region containing three copies of the Immunoglobulin domain (Pfam:PF00047), a single transmembrane region, and an intracellular region containing a Protein tyrosine kinase domain (Pfam:PF07714). Its active form binds fibroblast growth factor (FGF). FGFs and its receptor comprise a signaling system that is conserved throughout metazoan evolution. go-plus.json http://purl.obolibrary.org/obo/PR_000001349 GO:0000099 biolink:MolecularActivity sulfur amino acid transmembrane transporter activity Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives. go-plus.json sulfur amino acid transporter activity|sulphur amino acid transmembrane transporter activity|sulphur amino acid transporter activity http://purl.obolibrary.org/obo/GO_0000099 GO:0000098 biolink:BiologicalProcess sulfur amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. go-plus.json sulfur amino acid breakdown|sulphur amino acid catabolic process|sulphur amino acid catabolism|sulfur amino acid degradation|sulfur amino acid catabolism http://purl.obolibrary.org/obo/GO_0000098 CHEBI:63385 biolink:ChemicalSubstance hexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63385 GO:0000093 biolink:BiologicalProcess mitotic telophase The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. go-plus.json http://purl.obolibrary.org/obo/GO_0000093 gocheck_do_not_annotate CHEBI:63384 biolink:ChemicalSubstance ketoheptose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63384 GO:0000092 biolink:BiologicalProcess mitotic anaphase B The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0000092 gocheck_do_not_annotate GO:0000091 biolink:BiologicalProcess mitotic anaphase A The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0000091 gocheck_do_not_annotate CHEBI:63383 biolink:ChemicalSubstance heptose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63383 CHEBI:87331 biolink:ChemicalSubstance 17beta-hydroxy-5beta-androst-1-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87331 chebi_ph7_3 GO:0000090 biolink:BiologicalProcess mitotic anaphase The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0000090 gocheck_do_not_annotate GO:0000097 biolink:BiologicalProcess sulfur amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. go-plus.json sulfur amino acid biosynthesis|sulfur amino acid anabolism|sulfur amino acid synthesis|sulfur amino acid formation|sulphur amino acid biosynthesis|sulphur amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0000097 CHEBI:63389 biolink:ChemicalSubstance UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63389 chebi_ph7_3 CHEBI:87333 biolink:ChemicalSubstance 17beta-hydroxy-5beta-estran-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87333 chebi_ph7_3 GO:0000096 biolink:BiologicalProcess sulfur amino acid metabolic process The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine. go-plus.json sulfur amino acid metabolism|sulphur amino acid metabolic process|sulphur amino acid metabolism http://purl.obolibrary.org/obo/GO_0000096 GO:0000095 biolink:MolecularActivity S-adenosyl-L-methionine transmembrane transporter activity Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. Reactome:R-HSA-8855062 go-plus.json SAM transmembrane transporter activity|S-adenosylmethionine transmembrane transporter activity|S-adenosyl methionine permease activity|S-adenosylmethionine permease activity|S-adenosyl methionine transporter activity|S-adenosylmethionine transporter activity http://purl.obolibrary.org/obo/GO_0000095 GO:0000094 biolink:BiologicalProcess obsolete septin assembly and septum formation OBSOLETE. (Was not defined before being made obsolete). go-plus.json septin assembly and septum formation http://purl.obolibrary.org/obo/GO_0000094 PR:000001353 biolink:Protein granulocyte colony-stimulating factor receptor A protein that is a translation product of the human CSF3R gene or a 1:1 ortholog thereof. The active receptor is a homodimer which can bind G-CSF and transduce G-CSF-triggered growth signals into cells. Its extracellular domain contains a sequence of about 200 amino acids which can be found in various cytokine receptors. In addition, it contains an immunoglobulin-like domain and three fibronectin type III domains. go-plus.json G-CSF-R|CSF3R|CD114|G-CSF receptor|GCSFR|Csfgr http://purl.obolibrary.org/obo/PR_000001353 CHEBI:87339 biolink:ChemicalSubstance lipid A 1-(2-aminoethyl diphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87339 PR:000001357 biolink:Protein intercellular adhesion molecule 1/3 A protein with a core domain architecture consisting of an Intercellular adhesion molecule (ICAM), N-terminal domain (Pfam:PF03921), a type of Ig-like domain, and four copies of the Immunoglobulin domain (Pfam:PF00047), most of which are not detected by Pfam. go-plus.json ICAM http://purl.obolibrary.org/obo/PR_000001357 GO:0000068 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000068 GO:0000067 biolink:BiologicalProcess obsolete DNA replication and chromosome cycle OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA replication and chromosome cycle http://purl.obolibrary.org/obo/GO_0000067 GO:0000066 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000066 GO:0000065 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000065 CHEBI:63391 biolink:ChemicalSubstance ketohexose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63391 PR:000015975 biolink:Protein sperm motility kinase Tcr mutant form A protein that is a translation product of the mouse Smoktcr gene or a 1:1 ortholog thereof. go-plus.json responder protein Smok-Tcr|Tcr|dominant negative form of Smok|Smoktcr|SmokTcr http://purl.obolibrary.org/obo/PR_000015975 GO:0000069 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000069 GO:0000060 biolink:BiologicalProcess obsolete protein import into nucleus, translocation OBSOLETE. A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope. go-plus.json protein translocation during protein import into nucleus|protein import into cell nucleus, translocation|protein-nucleus import, translocation|protein transport from cytoplasm to nucleus, translocation|protein translocation during protein transport from cytoplasm to nucleus|protein translocation during protein-nucleus import http://purl.obolibrary.org/obo/GO_0000060 CHEBI:87362 biolink:ChemicalSubstance pentyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87362 chebi_ph7_3 CHEBI:63394 biolink:ChemicalSubstance ketoaldonic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63394 GO:0000064 biolink:MolecularActivity L-ornithine transmembrane transporter activity Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid. Reactome:R-HSA-70634 go-plus.json histidine/arginine/lysine/ornithine porter activity|L-ornithine transporter activity http://purl.obolibrary.org/obo/GO_0000064 GO:0000063 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000063 GO:0000062 biolink:MolecularActivity fatty-acyl-CoA binding Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group. go-plus.json fatty-acyl-coenzyme A binding|fatty-acyl binding http://purl.obolibrary.org/obo/GO_0000062 GO:0000061 biolink:BiologicalProcess obsolete protein import into nucleus, substrate release OBSOLETE. A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex. go-plus.json protein substrate release during protein transport from cytoplasm to nucleus|protein-nucleus import, substrate release|protein transport from cytoplasm to nucleus, substrate release|protein substrate release during protein import into nucleus|protein substrate release during protein-nucleus import|protein import into cell nucleus, substrate release http://purl.obolibrary.org/obo/GO_0000061 PR:000001327 biolink:Protein cadherin A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. go-plus.json http://purl.obolibrary.org/obo/PR_000001327 GO:0000079 biolink:BiologicalProcess regulation of cyclin-dependent protein serine/threonine kinase activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. go-plus.json regulation of cyclin-dependent protein kinase activity|regulation of CDK activity http://purl.obolibrary.org/obo/GO_0000079 GO:0000078 biolink:BiologicalProcess obsolete cytokinesis after mitosis checkpoint OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis. go-plus.json cell shape checkpoint|cell morphogenesis checkpoint http://purl.obolibrary.org/obo/GO_0000078 GO:0000077 biolink:BiologicalProcess DNA damage checkpoint signaling A signal transduction process that contributes to a DNA damage checkpoint. Wikipedia:Postreplication_checkpoint|Wikipedia:DNA_damage_checkpoint go-plus.json DNA damage response, signal transduction resulting in cell cycle arrest|signal transduction involved in DNA damage checkpoint|DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0000077 GO:0000076 biolink:BiologicalProcess DNA replication checkpoint signaling A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome. go-plus.json DNA replication checkpoint|signal transduction involved in DNA replication checkpoint http://purl.obolibrary.org/obo/GO_0000076 GO:0000071 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000071 CHEBI:167106 biolink:ChemicalSubstance androstane conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_167106 GO:0000070 biolink:BiologicalProcess mitotic sister chromatid segregation The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. go-plus.json mitotic sister-chromatid adhesion release|mitotic chromosome segregation http://purl.obolibrary.org/obo/GO_0000070 goslim_pombe CHEBI:167105 biolink:ChemicalSubstance cholestane conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_167105 CHEBI:167108 biolink:ChemicalSubstance pregnane conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_167108 CHEBI:167107 biolink:ChemicalSubstance estrane conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_167107 GO:0000075 biolink:BiologicalProcess cell cycle checkpoint signaling A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction. Wikipedia:Cell_cycle_checkpoint go-plus.json signal transduction involved in G2/M transition checkpoint|G1/S transition checkpoint|G2/M checkpoint|G2/M transition checkpoint|cell cycle checkpoint|G1/S checkpoint|signal transduction involved in cell cycle checkpoint http://purl.obolibrary.org/obo/GO_0000075 gocheck_do_not_annotate CHEBI:87356 biolink:ChemicalSubstance (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87356 chebi_ph7_3 GO:0000074 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000074 GO:0000073 biolink:BiologicalProcess initial mitotic spindle pole body separation The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB. go-plus.json http://purl.obolibrary.org/obo/GO_0000073 CHEBI:167104 biolink:ChemicalSubstance seco-cholestane conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_167104 GO:0000072 biolink:BiologicalProcess obsolete M phase specific microtubule process OBSOLETE. A microtubule-based process that occurs only during M phase of the cell cycle. go-plus.json M-phase specific microtubule process|M phase specific microtubule process http://purl.obolibrary.org/obo/GO_0000072 CHEBI:167109 biolink:ChemicalSubstance acyl sugars go-plus.json http://purl.obolibrary.org/obo/CHEBI_167109 PR:000001335 biolink:Protein class 2 cytokine, IL-10 type A protein with a core domain architecture consisting of an N-terminal Interleukin 10 (Pfam:PF00726) domain. go-plus.json http://purl.obolibrary.org/obo/PR_000001335 CHEBI:28968 biolink:ChemicalSubstance N'-phosphoguanidinoethyl methyl hydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28968 GO:0097199 biolink:MolecularActivity cysteine-type endopeptidase activity involved in apoptotic signaling pathway Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. go-plus.json initiator caspase activity|apical caspase activity|activator caspase activity|cysteine-type endopeptidase activity involved in apoptotic signalling pathway http://purl.obolibrary.org/obo/GO_0097199 CHEBI:28969 biolink:ChemicalSubstance N,N-dimethyltryptamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28969 GO:0097196 biolink:CellularComponent Shu complex A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p. go-plus.json http://purl.obolibrary.org/obo/GO_0097196 GO:0097195 biolink:BiologicalProcess pilomotor reflex The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect. go-plus.json horripilation|goosebump reflex|piloerection http://purl.obolibrary.org/obo/GO_0097195 CHEBI:28963 biolink:ChemicalSubstance amino sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_28963 GO:0097198 biolink:BiologicalProcess histone H3-K36 trimethylation The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0097198 CHEBI:28966 biolink:ChemicalSubstance chlorophyll go-plus.json http://purl.obolibrary.org/obo/CHEBI_28966 GO:0097197 biolink:CellularComponent tetraspanin-enriched microdomain A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities. go-plus.json membrane tetraspanin-enriched microdomain|TEM http://purl.obolibrary.org/obo/GO_0097197 CHEBI:28965 biolink:ChemicalSubstance dicarboxylic acid dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_28965 chebi_ph7_3 GO:0097192 biolink:BiologicalProcess extrinsic apoptotic signaling pathway in absence of ligand A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered. go-plus.json extrinsic apoptotic signalling pathway in absence of ligand|dependence receptor signaling pathway|extrinsic apoptosis in absence of ligand http://purl.obolibrary.org/obo/GO_0097192 GO:0097191 biolink:BiologicalProcess extrinsic apoptotic signaling pathway A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. go-plus.json extrinsic apoptotic signaling pathway in presence of ligand|extrinsic apoptosis|death receptor-mediated apoptosis|extrinsic apoptotic signalling pathway|extrinsic apoptotic pathway http://purl.obolibrary.org/obo/GO_0097191 GO:0097194 biolink:BiologicalProcess execution phase of apoptosis A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. go-plus.json apoptosis|execution phase of apoptotic process http://purl.obolibrary.org/obo/GO_0097194 UBERON:0035322 biolink:AnatomicalEntity right common iliac artery go-plus.json trunk of right common iliac arterial tree http://purl.obolibrary.org/obo/UBERON_0035322 GO:0097193 biolink:BiologicalProcess intrinsic apoptotic signaling pathway A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP). go-plus.json mitochondrial-mediated apoptotic pathway|intrinsic apoptotic signalling pathway|induction of apoptosis by intracellular signals|intrinsic apoptosis|intrinsic apoptotic pathway http://purl.obolibrary.org/obo/GO_0097193 CHEBI:28961 biolink:ChemicalSubstance 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28961 GO:0097190 biolink:BiologicalProcess apoptotic signaling pathway A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. go-plus.json apoptotic signalling pathway|induction of apoptosis by extracellular signals http://purl.obolibrary.org/obo/GO_0097190 UBERON:0035316 biolink:AnatomicalEntity prostatic capsule The membrane the surrounds the prostate gland. go-plus.json capsule of prostate gland|capsule of prostate http://purl.obolibrary.org/obo/UBERON_0035316 CHEBI:14314 biolink:ChemicalSubstance D-glucose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_14314 CHEBI:77901 biolink:ChemicalSubstance anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77901 chebi_ph7_3 CHEBI:77900 biolink:ChemicalSubstance (1'S,5'S)-5'-hydroxyaverantin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77900 chebi_ph7_3 CHEBI:77906 biolink:ChemicalSubstance minocycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77906 chebi_ph7_3 CHEBI:28975 biolink:ChemicalSubstance 2,5-dichloro-2,5-cyclohexadiene-1,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28975 chebi_ph7_3 CHEBI:77904 biolink:ChemicalSubstance norsolorinic acid anthrone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77904 chebi_ph7_3 CHEBI:28977 biolink:ChemicalSubstance 2-hydroxy-3-carboxylato-6-oxo-7-methylocta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28977 chebi_ph7_3 CHEBI:28976 biolink:ChemicalSubstance carbonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28976 CHEBI:28972 biolink:ChemicalSubstance (R)-propane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28972 chebi_ph7_3 CHEBI:77907 biolink:ChemicalSubstance hydroxyversicolorone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77907 chebi_ph7_3 NCBITaxon:169748 biolink:OrganismalEntity Phoeniceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_169748 GO:0097178 biolink:BiologicalProcess ruffle assembly The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. go-plus.json membrane ruffling|membrane ruffle formation http://purl.obolibrary.org/obo/GO_0097178 CHEBI:28946 biolink:ChemicalSubstance theobromine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28946 chebi_ph7_3 CHEBI:77913 biolink:ChemicalSubstance 9(R)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77913 chebi_ph7_3 GO:0097177 biolink:MolecularActivity mitochondrial ribosome binding Binding to a mitochondrial ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0097177 CHEBI:28948 biolink:ChemicalSubstance gramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28948 GO:0097179 biolink:CellularComponent protease inhibitor complex A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity. go-plus.json peptidase inhibitor complex http://purl.obolibrary.org/obo/GO_0097179 CHEBI:28947 biolink:ChemicalSubstance (5-oxo-2-sulfo-2,5-dihydrofuran-2-yl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28947 GO:0097174 biolink:BiologicalProcess 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid. go-plus.json 1,6-anhydro-N-acetylmuramic acid metabolic process|1,6-anhydro-N-acetyl-beta-muramate metabolic process|1,6-anhydro-N-acetyl-beta-muramic acid metabolism|1,6-anhydro-N-acetyl-beta-muramate metabolism|1,6-anhydro-N-acetylmuramic acid metabolism http://purl.obolibrary.org/obo/GO_0097174 CHEBI:28942 biolink:ChemicalSubstance CDP-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28942 GO:0097173 biolink:BiologicalProcess N-acetylmuramic acid catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine. go-plus.json N-acetylmuramate breakdown|N-acetylmuramic acid catabolism|N-acetylmuramate catabolic process|N-acetylmuramic acid degradation|N-acetylmuramic acid breakdown|N-acetylmuramate catabolism|N-acetylmuramate degradation http://purl.obolibrary.org/obo/GO_0097173 CHEBI:28941 biolink:ChemicalSubstance docosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28941 GO:0097176 biolink:BiologicalProcess epoxide metabolic process The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers. go-plus.json epoxide metabolism http://purl.obolibrary.org/obo/GO_0097176 CHEBI:28944 biolink:ChemicalSubstance N-acetyl-7-O-acetylneuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28944 chebi_ph7_3 CHEBI:77914 biolink:ChemicalSubstance 3-methylbut-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_77914 chebi_ph7_3 GO:0097175 biolink:BiologicalProcess 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid. go-plus.json 1,6-anhydro-N-acetylmuramate catabolism|1,6-anhydro-N-acetyl-beta-muramic acid catabolism|1,6-anhydro-N-acetylmuramic acid degradation|1,6-anhydro-N-acetyl-beta-muramate degradation|1,6-anhydro-N-acetylmuramic acid breakdown|1,6-anhydro-N-acetyl-beta-muramate breakdown|1,6-anhydro-N-acetylmuramic acid catabolic process|1,6-anhydro-N-acetyl-beta-muramate catabolic process|1,6-anhydro-N-acetyl-beta-muramate catabolism|1,6-anhydro-N-acetylmuramic acid catabolism|1,6-anhydro-N-acetyl-beta-muramic acid degradation|1,6-anhydro-N-acetylmuramate degradation|1,6-anhydro-N-acetyl-beta-muramic acid breakdown|1,6-anhydro-N-acetylmuramate breakdown|1,6-anhydro-N-acetylmuramate catabolic process http://purl.obolibrary.org/obo/GO_0097175 CHEBI:28943 biolink:ChemicalSubstance N-acylsphingosine 1-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28943 GO:0097170 biolink:BiologicalProcess ADP-L-glycero-beta-D-manno-heptose metabolic process The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate. go-plus.json ADP-L-glycero-beta-D-manno-heptose metabolism http://purl.obolibrary.org/obo/GO_0097170 GO:0097172 biolink:BiologicalProcess N-acetylmuramic acid metabolic process The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine. go-plus.json N-acetylmuramic acid metabolism|N-acetylmuramate metabolism|N-acetylmuramate metabolic process http://purl.obolibrary.org/obo/GO_0097172 CHEBI:77919 biolink:ChemicalSubstance (7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77919 chebi_ph7_3 CHEBI:28940 biolink:ChemicalSubstance calciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28940 chebi_ph7_3 GO:0097171 biolink:BiologicalProcess ADP-L-glycero-beta-D-manno-heptose biosynthetic process The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate. go-plus.json ADP-L-glycero-beta-D-manno-heptose formation|ADP-L-glycero-beta-D-manno-heptose biosynthesis|ADP-L-glycero-beta-D-manno-heptose anabolism|ADP-L-glycero-beta-D-manno-heptose synthesis http://purl.obolibrary.org/obo/GO_0097171 UBERON:0011332 biolink:AnatomicalEntity extrinsic tongue pre-muscle mass go-plus.json http://purl.obolibrary.org/obo/UBERON_0011332 CHEBI:14336 biolink:ChemicalSubstance glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_14336 GO:0097189 biolink:CellularComponent apoptotic body A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um. go-plus.json apoptotic bleb|apoptotic vesicle http://purl.obolibrary.org/obo/GO_0097189 GO:0097188 biolink:BiologicalProcess dentin mineralization The process in which calcium salts are deposited into the calcareous tooth structure known as dentin. go-plus.json dentine mineralization http://purl.obolibrary.org/obo/GO_0097188 CHEBI:28956 biolink:ChemicalSubstance cobinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28956 CHEBI:77922 biolink:ChemicalSubstance isopentenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77922 chebi_ph7_3 GO:0097185 biolink:BiologicalProcess cellular response to azide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097185 UBERON:0001997 biolink:AnatomicalEntity olfactory epithelium A sensory epithelium inside the nasal cavity that is responsible for detecting odors[WP]. go-plus.json MOE|sensory olfactory epithelium|olfactory sensory epithelium|nasal sensory epithelium|nasal epithelium|nasal cavity olfactory epithelium|olfactory membrane|pseudostratified main olfactory epithelium|main olfactory epithelium http://purl.obolibrary.org/obo/UBERON_0001997 CHEBI:28952 biolink:ChemicalSubstance 5alpha-pregnane-3,20-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_28952 chebi_ph7_3 CHEBI:77927 biolink:ChemicalSubstance nonan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_77927 chebi_ph7_3 GO:0097184 biolink:BiologicalProcess response to azide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097184 GO:0097187 biolink:BiologicalProcess dentinogenesis The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. go-plus.json dentine development|dentin development http://purl.obolibrary.org/obo/GO_0097187 CHEBI:28955 biolink:ChemicalSubstance 2-methoxy-17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28955 chebi_ph7_3 GO:0097186 biolink:BiologicalProcess amelogenesis The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. go-plus.json enamel development http://purl.obolibrary.org/obo/GO_0097186 GO:0097181 biolink:CellularComponent protein C inhibitor-coagulation factor V complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V. go-plus.json protein C inhibitor-F5 complex|PCI-coagulation factor V complex|serpin A5-coagulation factor V complex|plasma serine protease inhibitor-coagulation factor V complex|SERPINA5-coagulation factor V complex http://purl.obolibrary.org/obo/GO_0097181 GO:0097180 biolink:CellularComponent serine protease inhibitor complex A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity. go-plus.json serine-type endopeptidase inhibitor complex|serpin complex http://purl.obolibrary.org/obo/GO_0097180 GO:0097183 biolink:CellularComponent protein C inhibitor-coagulation factor XI complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI. go-plus.json PCI-coagulation factor XI complex|protein C inhibitor-F11 complex|SERPINA5-coagulation factor XI complex|plasma serine protease inhibitor-coagulation factor XI complex|serpin A5-coagulation factor XI complex http://purl.obolibrary.org/obo/GO_0097183 CHEBI:28951 biolink:ChemicalSubstance (9S,10S)-9,10-dihydrophenanthrene-9,10-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28951 chebi_ph7_3 GO:0097182 biolink:CellularComponent protein C inhibitor-coagulation factor Xa complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa. go-plus.json serpin A5-coagulation factor Xa complex|PCI-coagulation factor Xa complex|SERPINA5-coagulation factor Xa complex|plasma serine protease inhibitor-coagulation factor Xa complex http://purl.obolibrary.org/obo/GO_0097182 CHEBI:14321 biolink:ChemicalSubstance glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_14321 chebi_ph7_3 CHEBI:77935 biolink:ChemicalSubstance cyanidin 3-O-beta-D-galactoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77935 chebi_ph7_3 CHEBI:77933 biolink:ChemicalSubstance (S)-5'-oxoaverantin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77933 chebi_ph7_3 CHEBI:77932 biolink:ChemicalSubstance tetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77932 chebi_ph7_3 CHEBI:77939 biolink:ChemicalSubstance oroxylin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77939 chebi_ph7_3 CHEBI:77938 biolink:ChemicalSubstance barbiturate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77938 chebi_ph7_3 NCBITaxon:51967 biolink:OrganismalEntity Candidatus Korarchaeota go-plus.json Xenarchaea|Xenarchaeota|Korarchaeota http://purl.obolibrary.org/obo/NCBITaxon_51967 CHEBI:28928 biolink:ChemicalSubstance angelicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28928 chebi_ph7_3 CHEBI:77931 biolink:ChemicalSubstance cyanidin 3-O-{6-O-[6-O-(4-coumaroyl)-beta-D-glucosyl]-2-O-beta-D-xylosyl-beta-D-galactoside}(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77931 chebi_ph7_3 CHEBI:28927 biolink:ChemicalSubstance sakuranetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28927 chebi_ph7_3 CHEBI:28935 biolink:ChemicalSubstance (E)-hexadec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28935 CHEBI:77946 biolink:ChemicalSubstance anthocyanidin 3-O-sophoroside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77946 chebi_ph7_3 CHEBI:77945 biolink:ChemicalSubstance anthocyanidin 3-O-beta-D-sambubioside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77945 chebi_ph7_3 CHEBI:28934 biolink:ChemicalSubstance vitamin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28934 chebi_ph7_3 CHEBI:77944 biolink:ChemicalSubstance anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77944 chebi_ph7_3 CHEBI:28937 biolink:ChemicalSubstance (-)-abscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28937 CHEBI:77943 biolink:ChemicalSubstance anthocyanidin 3-glucoside 5-[(6-O-4-hydroxycinnamoyl)glucoside] betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77943 chebi_ph7_3 CHEBI:28936 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28936 CHEBI:28931 biolink:ChemicalSubstance 3'-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28931 CHEBI:77948 biolink:ChemicalSubstance isoliquiritigenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77948 chebi_ph7_3 CHEBI:77947 biolink:ChemicalSubstance (S)-versiconol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77947 chebi_ph7_3 CHEBI:63300 biolink:ChemicalSubstance osmoregulated periplasmic glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_63300 CHEBI:63305 biolink:ChemicalSubstance dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63305 chebi_ph7_3 CHEBI:63304 biolink:ChemicalSubstance dTDP-D-ravidosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63304 chebi_ph7_3 CHEBI:63303 biolink:ChemicalSubstance dTDP-3-dehydro-6-deoxy-alpha-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63303 chebi_ph7_3 CHEBI:63302 biolink:ChemicalSubstance dTDP-3-dehydro-6-deoxy-alpha-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63302 CHEBI:63309 biolink:ChemicalSubstance mycinamicin cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_63309 CHEBI:63308 biolink:ChemicalSubstance mycinamicin III(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63308 chebi_ph7_3 CHEBI:63307 biolink:ChemicalSubstance 10-deoxymethymycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63307 chebi_ph7_3 CHEBI:28939 biolink:ChemicalSubstance N-acetyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28939 CHEBI:77941 biolink:ChemicalSubstance EC 3.5.1.4 (amidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77941 CHEBI:28938 biolink:ChemicalSubstance ammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_28938 chebi_ph7_3 CHEBI:28902 biolink:ChemicalSubstance N-phenylhydroxylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28902 chebi_ph7_3 CHEBI:77956 biolink:ChemicalSubstance L-erythro-sphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77956 chebi_ph7_3 CHEBI:28903 biolink:ChemicalSubstance decan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28903 chebi_ph7_3 UBERON:0011370 biolink:AnatomicalEntity transverse process of atlas A transverse process of vertebra that is part of a vertebral bone 1. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011370 OBO:uberon/core#proximally_connected_to biolink:OntologyClass proximally connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. proximally_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to CHEBI:28900 biolink:ChemicalSubstance N-alkylphthalic monoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28900 CHEBI:63311 biolink:ChemicalSubstance mycinamicin VI(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63311 chebi_ph7_3 CHEBI:63310 biolink:ChemicalSubstance mycinamicin IV(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63310 chebi_ph7_3 NCBITaxon:2419 biolink:OrganismalEntity Thermotogales go-plus.json thermotogales http://purl.obolibrary.org/obo/NCBITaxon_2419 CHEBI:63319 biolink:ChemicalSubstance D-erythritol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63319 CHEBI:28909 biolink:ChemicalSubstance iprodione go-plus.json http://purl.obolibrary.org/obo/CHEBI_28909 chebi_ph7_3 CHEBI:28905 biolink:ChemicalSubstance prop-2-yn-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28905 chebi_ph7_3 CHEBI:77951 biolink:ChemicalSubstance versicolorin B(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77951 chebi_ph7_3 CHEBI:28907 biolink:ChemicalSubstance 2,3-bisphosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28907 CHEBI:77950 biolink:ChemicalSubstance (2S-3S)-versiconal hemiacetal(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77950 chebi_ph7_3 CHEBI:28913 biolink:ChemicalSubstance (2E)-hexenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_28913 chebi_ph7_3 CHEBI:77968 biolink:ChemicalSubstance humectant go-plus.json http://purl.obolibrary.org/obo/CHEBI_77968 CHEBI:77966 biolink:ChemicalSubstance food stabiliser go-plus.json http://purl.obolibrary.org/obo/CHEBI_77966 CHEBI:28915 biolink:ChemicalSubstance fosfomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28915 CHEBI:77965 biolink:ChemicalSubstance food anticaking agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_77965 CHEBI:28914 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28914 CHEBI:28911 biolink:ChemicalSubstance cob(III)alamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28911 chebi_ph7_3 CHEBI:77969 biolink:ChemicalSubstance food humectant go-plus.json http://purl.obolibrary.org/obo/CHEBI_77969 UBERON:0011363 biolink:AnatomicalEntity cranial lymph vasculature A lymph vasculature that is part of a head. go-plus.json cranial lymphatics|set of cranial lymphatic vessels|cranial lymph vessels|cranial lymph vessel|set of lymphatic vessels of head http://purl.obolibrary.org/obo/UBERON_0011363 UBERON:0011362 biolink:AnatomicalEntity cranial blood vasculature A blood vasculature that is part of a head. go-plus.json set of blood vessels of head|cranial blood vessels|cranial blood vessel http://purl.obolibrary.org/obo/UBERON_0011362 CHEBI:63323 biolink:ChemicalSubstance 9(R)-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63323 chebi_ph7_3 CHEBI:63322 biolink:ChemicalSubstance (S)-2-hydroxy-3-oxo-4-(phosphonooxy)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63322 CHEBI:63325 biolink:ChemicalSubstance (2R,3S)-2,4',7-trihydroxyisoflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_63325 chebi_ph7_3 CHEBI:63324 biolink:ChemicalSubstance (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63324 chebi_ph7_3 CHEBI:63328 biolink:ChemicalSubstance 4'-hydroxyisoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_63328 chebi_ph7_3 CHEBI:77964 biolink:ChemicalSubstance anticaking agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_77964 CHEBI:77962 biolink:ChemicalSubstance food antioxidant go-plus.json http://purl.obolibrary.org/obo/CHEBI_77962 CHEBI:28919 biolink:ChemicalSubstance estrone 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_28919 CHEBI:28918 biolink:ChemicalSubstance (R)-adrenaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28918 CHEBI:77961 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycerol 3-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77961 GO:0000200 biolink:BiologicalProcess obsolete inactivation of MAPK activity involved in cell wall organization or biogenesis OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis. go-plus.json termination of MAPK activity during cell wall biogenesis|inactivation of MAPK activity involved in cell wall organization or biogenesis|cell wall biogenesis, termination of MAPK activity|inactivation of MAPK activity involved in cell wall integrity|cell wall biogenesis, inactivation of MAPK activity http://purl.obolibrary.org/obo/GO_0000200 GO:0097112 biolink:BiologicalProcess gamma-aminobutyric acid receptor clustering The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane. go-plus.json GABA receptor clustering http://purl.obolibrary.org/obo/GO_0097112 GO:0048189 biolink:CellularComponent Lid2 complex A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1. go-plus.json http://purl.obolibrary.org/obo/GO_0048189 GO:0048188 biolink:CellularComponent Set1C/COMPASS complex A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. go-plus.json Set1C|Set1/COMPASS complex|COMPASS complex http://purl.obolibrary.org/obo/GO_0048188 GO:0097111 biolink:BiologicalProcess endoplasmic reticulum-Golgi intermediate compartment organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment. go-plus.json ERGIC organization|endoplasmic reticulum-Golgi intermediate compartment organisation|endoplasmic reticulum-Golgi intermediate compartment organization and biogenesis|ER-Golgi intermediate compartment organization http://purl.obolibrary.org/obo/GO_0097111 UBERON:0001946 biolink:AnatomicalEntity inferior colliculus Part of the midbrain tectum, consisting of paired predominantly gray matter elevations on the dorsal aspect of the midbrain, located caudal to the superior colliculus, dorsal to the periaqueductal gray of the cerebral aqueduct and rostral to the cerebellum. According to Neuronames, the inferior colliculus comprises the central, pericentral and external nucleus and two predominantly white matter structures, the brachium of the inferior colliculus and the commissure of the inferior colliculus (MM). go-plus.json posterior corpus quadrigeminum|corpus bigeminalis caudalis|corpus bigeminum posterioris|inferior colliculi|caudal colliculus|colliculus caudalis|corpus quadrigeminum inferius|colliculus inferior|posterior colliculus http://purl.obolibrary.org/obo/UBERON_0001946 GO:0097114 biolink:BiologicalProcess NMDA glutamate receptor clustering The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane. go-plus.json N-methyl-D-aspartate receptor clustering|NMDA receptor clustering http://purl.obolibrary.org/obo/GO_0097114 GO:0048187 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048187 UBERON:0001949 biolink:AnatomicalEntity gingival epithelium A stratified squamous epithelium consisting of a basal layer; it is keratinized or parakeratinized[BTO]. go-plus.json gingiva epithelium|epithelium of gingiva|epithelial tissue of gingiva|gingiva epithelial tissue http://purl.obolibrary.org/obo/UBERON_0001949 GO:0048186 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048186 GO:0097113 biolink:BiologicalProcess AMPA glutamate receptor clustering The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane. go-plus.json alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|AMPA receptor clustering http://purl.obolibrary.org/obo/GO_0097113 UBERON:0001948 biolink:AnatomicalEntity regional part of spinal cord A multi-tissue structure that is part of a spinal cord. go-plus.json spinal cord part http://purl.obolibrary.org/obo/UBERON_0001948 UBERON:0001943 biolink:AnatomicalEntity midbrain tegmentum Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. go-plus.json MTg|tegmentum mesencephali|mesencephalic tegmentum|tegmentum of midbrain|tegmentum mesencephalicum|tegmentum http://purl.obolibrary.org/obo/UBERON_0001943 GO:0000204 biolink:BiologicalProcess obsolete activation of MAPKK during sporulation (sensu Saccharomyces) OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). go-plus.json activation of MAPKK during sporulation (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000204 GO:0048185 biolink:MolecularActivity activin binding Binding to activin, a dimer of inhibin-beta subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0048185 GO:0000203 biolink:BiologicalProcess obsolete activation of MAPKKK during sporulation (sensu Saccharomyces) OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). go-plus.json activation of MAPKKK during sporulation (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000203 GO:0048184 biolink:MolecularActivity obsolete follistatin binding OBSOLETE. Binding to the peptide hormone follistatin. go-plus.json follistatin binding http://purl.obolibrary.org/obo/GO_0048184 GO:0000202 biolink:BiologicalProcess obsolete MAPKKK cascade during sporulation (sensu Saccharomyces) OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). go-plus.json MAPKKK cascade during sporulation (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000202 UBERON:0001945 biolink:AnatomicalEntity superior colliculus Part of the midbrain tecturm consisting of paired bodies that sit caudal to the thalamus and surround the pineal gland in the mesencephalon of vertebrate brains. It comprises the rostral aspect of the midbrain, posterior to the periaqueductal gray and adjacent superior the inferior colliculus. The inferior and superior colliculi are known collectively as the corpora quadrigemina (Latin, quadruplet bodies). It consists of several identified cellular layers and also comprises the brachium of the superior colliculus and commissure of supeior colliculus from Wikipedia.org and Neuronames (MM). go-plus.json colliculus cranialis|colliculus bigeminalis oralis|tectum|tectal lobe|optic lobe|dorsal midbrain|strata (grisea et alba) colliculi superioris|colliculus superior|corpus quadrigeminum superius|optic tectum|layers of the superior colliculus|nates|optic tectum|anterior colliculus|cranial colliculus|lobus opticus|strata (grisea et alba) colliculi cranialis|colliculus rostralis|anterior corpus quadrigeminum|corpora bigemina|tectum opticum http://purl.obolibrary.org/obo/UBERON_0001945 GO:0048183 biolink:CellularComponent activin AB complex A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B. go-plus.json inhibin beta-B|inhibin beta-A http://purl.obolibrary.org/obo/GO_0048183 GO:0097110 biolink:MolecularActivity scaffold protein binding Binding to a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0097110 GO:0000201 biolink:BiologicalProcess obsolete MAPK import into nucleus involved in cell wall organization or biogenesis OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis. go-plus.json cell wall biogenesis, MAPK import into nucleus|nuclear translocation of MAPK involved in cell wall biogenesis|nuclear translocation of MAPK involved in cell wall integrity|MAPK import into nucleus involved in cell wall integrity|MAPK import into nucleus involved in cell wall biogenesis|cell wall biogenesis, nuclear translocation of MAPK http://purl.obolibrary.org/obo/GO_0000201 UBERON:0001944 biolink:AnatomicalEntity pretectal region Nuclear complex between dorsal thalamus and optic tectum whose nuclei receive afferents primarily from the retina and the optic tectum and are involved in modulating motor behavior in response to visual input. go-plus.json nuclei pretectales|regio pretectalis|area praetectalis|area pretectalis|nucleus praetectalis|pretectal nuclei|pretectal area|pretectum|praetectum http://purl.obolibrary.org/obo/UBERON_0001944 GO:0048182 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048182 GO:0014849 biolink:BiologicalProcess ureter smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0014849 GO:0014848 biolink:BiologicalProcess urinary tract smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. go-plus.json http://purl.obolibrary.org/obo/GO_0014848 GO:0014847 biolink:BiologicalProcess proximal stomach smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach. go-plus.json http://purl.obolibrary.org/obo/GO_0014847 GO:1903589 biolink:BiologicalProcess positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. go-plus.json up regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|positive regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|up regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|activation of blood vessel endothelial cell proliferation during sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|up-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|up-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|activation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis http://purl.obolibrary.org/obo/GO_1903589 GO:0014846 biolink:BiologicalProcess esophagus smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract. go-plus.json oesophagus smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014846 GO:1903588 biolink:BiologicalProcess negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. go-plus.json down regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|negative regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|down regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation during sprouting angiogenesis http://purl.obolibrary.org/obo/GO_1903588 GO:1903587 biolink:BiologicalProcess regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. go-plus.json regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis http://purl.obolibrary.org/obo/GO_1903587 GO:1903586 biolink:BiologicalProcess positive regulation of histone deubiquitination Any process that activates or increases the frequency, rate or extent of histone deubiquitination. go-plus.json up-regulation of histone deubiquitinylation|activation of histone deubiquitinylation|upregulation of histone deubiquitination|positive regulation of histone deubiquitylation|up regulation of histone deubiquitylation|positive regulation of histone deubiquitinylation|activation of histone deubiquitination|up regulation of histone deubiquitinylation|up-regulation of histone deubiquitination|upregulation of histone deubiquitylation|upregulation of histone deubiquitinylation|up regulation of histone deubiquitination|up-regulation of histone deubiquitylation|activation of histone deubiquitylation http://purl.obolibrary.org/obo/GO_1903586 GO:1903585 biolink:BiologicalProcess negative regulation of histone deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination. go-plus.json down regulation of histone deubiquitination|down-regulation of histone deubiquitylation|negative regulation of histone deubiquitylation|inhibition of histone deubiquitination|down-regulation of histone deubiquitinylation|negative regulation of histone deubiquitinylation|downregulation of histone deubiquitylation|down regulation of histone deubiquitylation|downregulation of histone deubiquitinylation|inhibition of histone deubiquitylation|down regulation of histone deubiquitinylation|down-regulation of histone deubiquitination|inhibition of histone deubiquitinylation|downregulation of histone deubiquitination http://purl.obolibrary.org/obo/GO_1903585 GO:1903595 biolink:BiologicalProcess positive regulation of histamine secretion by mast cell Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell. go-plus.json up-regulation of histamine secretion by mast cell|activation of histamine secretion by mast cell|up regulation of histamine secretion by mast cell|upregulation of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_1903595 GO:0014841 biolink:BiologicalProcess skeletal muscle satellite cell proliferation The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. go-plus.json http://purl.obolibrary.org/obo/GO_0014841 GO:1903594 biolink:BiologicalProcess negative regulation of histamine secretion by mast cell Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell. go-plus.json down-regulation of histamine secretion by mast cell|downregulation of histamine secretion by mast cell|down regulation of histamine secretion by mast cell|inhibition of histamine secretion by mast cell http://purl.obolibrary.org/obo/GO_1903594 GO:1903593 biolink:BiologicalProcess regulation of histamine secretion by mast cell Any process that modulates the frequency, rate or extent of histamine secretion by mast cell. go-plus.json http://purl.obolibrary.org/obo/GO_1903593 GO:1903592 biolink:BiologicalProcess positive regulation of lysozyme activity Any process that activates or increases the frequency, rate or extent of lysozyme activity. go-plus.json upregulation of lysozyme activity|activation of lysozyme g|upregulation of muramidase activity|up-regulation of PR1-lysozyme|up regulation of 1,4-N-acetylmuramidase activity|upregulation of peptidoglycan N-acetylmuramoylhydrolase activity|positive regulation of 1,4-N-acetylmuramidase activity|positive regulation of lysozyme g|activation of 1,4-N-acetylmuramidase activity|up-regulation of globulin G|up-regulation of L-7001|up regulation of lysozyme g|upregulation of N,O-diacetylmuramidase activity|up regulation of globulin G1|up regulation of mucopeptide glucohydrolase activity|upregulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of PR1-lysozyme|positive regulation of mucopeptide glucohydrolase activity|activation of mucopeptide glucohydrolase activity|positive regulation of globulin G1|up regulation of lysozyme activity|activation of lysozyme activity|up regulation of muramidase activity|activation of L-7001|up-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|activation of globulin G|activation of peptidoglycan N-acetylmuramoylhydrolase activity|positive regulation of muramidase activity|activation of muramidase activity|positive regulation of PR1-lysozyme|activation of globulin G1|up-regulation of 1,4-N-acetylmuramidase activity|up regulation of PR1-lysozyme|upregulation of lysozyme g|positive regulation of globulin G|up regulation of N,O-diacetylmuramidase activity|positive regulation of L-7001|up-regulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of N,O-diacetylmuramidase activity|positive regulation of N,O-diacetylmuramidase activity|up regulation of L-7001|up regulation of globulin G|activation of mucopeptide N-acetylmuramoylhydrolase activity|up-regulation of globulin G1|up-regulation of mucopeptide glucohydrolase activity|up-regulation of lysozyme activity|positive regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up-regulation of muramidase activity|upregulation of 1,4-N-acetylmuramidase activity|upregulation of PR1-lysozyme|up-regulation of lysozyme g|upregulation of L-7001|upregulation of globulin G|positive regulation of mucopeptide N-acetylmuramoylhydrolase activity|upregulation of mucopeptide glucohydrolase activity|upregulation of globulin G1|up-regulation of N,O-diacetylmuramidase activity|up regulation of mucopeptide N-acetylmuramoylhydrolase activity http://purl.obolibrary.org/obo/GO_1903592 GO:1903591 biolink:BiologicalProcess negative regulation of lysozyme activity Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity. go-plus.json down regulation of globulin G1|inhibition of globulin G|inhibition of L-7001|down regulation of mucopeptide glucohydrolase activity|down-regulation of lysozyme g|negative regulation of lysozyme g|downregulation of mucopeptide N-acetylmuramoylhydrolase activity|inhibition of peptidoglycan N-acetylmuramoylhydrolase activity|down regulation of lysozyme activity|down regulation of muramidase activity|downregulation of mucopeptide glucohydrolase activity|downregulation of globulin G1|down regulation of mucopeptide N-acetylmuramoylhydrolase activity|downregulation of lysozyme activity|inhibition of mucopeptide N-acetylmuramoylhydrolase activity|negative regulation of 1,4-N-acetylmuramidase activity|down-regulation of 1,4-N-acetylmuramidase activity|downregulation of muramidase activity|negative regulation of PR1-lysozyme|down-regulation of PR1-lysozyme|down regulation of N,O-diacetylmuramidase activity|downregulation of lysozyme g|down-regulation of globulin G|down-regulation of L-7001|negative regulation of globulin G|negative regulation of L-7001|down-regulation of mucopeptide glucohydrolase activity|negative regulation of globulin G1|negative regulation of mucopeptide glucohydrolase activity|down-regulation of globulin G1|downregulation of N,O-diacetylmuramidase activity|down regulation of lysozyme g|inhibition of 1,4-N-acetylmuramidase activity|down-regulation of lysozyme activity|negative regulation of muramidase activity|down-regulation of muramidase activity|down-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|downregulation of PR1-lysozyme|negative regulation of peptidoglycan N-acetylmuramoylhydrolase activity|inhibition of mucopeptide glucohydrolase activity|inhibition of lysozyme g|downregulation of L-7001|downregulation of globulin G|inhibition of lysozyme activity|negative regulation of N,O-diacetylmuramidase activity|down-regulation of N,O-diacetylmuramidase activity|down regulation of PR1-lysozyme|down-regulation of mucopeptide N-acetylmuramoylhydrolase activity|negative regulation of mucopeptide N-acetylmuramoylhydrolase activity|inhibition of muramidase activity|down regulation of L-7001|down regulation of globulin G|inhibition of globulin G1|downregulation of peptidoglycan N-acetylmuramoylhydrolase activity|down regulation of 1,4-N-acetylmuramidase activity|inhibition of PR1-lysozyme|inhibition of N,O-diacetylmuramidase activity|down regulation of peptidoglycan N-acetylmuramoylhydrolase activity|downregulation of 1,4-N-acetylmuramidase activity http://purl.obolibrary.org/obo/GO_1903591 GO:0014845 biolink:BiologicalProcess stomach body smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined. go-plus.json http://purl.obolibrary.org/obo/GO_0014845 GO:1903590 biolink:BiologicalProcess regulation of lysozyme activity Any process that modulates the frequency, rate or extent of lysozyme activity. go-plus.json regulation of mucopeptide glucohydrolase activity|regulation of globulin G1|regulation of mucopeptide N-acetylmuramoylhydrolase activity|regulation of muramidase activity|regulation of lysozyme g|regulation of N,O-diacetylmuramidase activity|regulation of PR1-lysozyme|regulation of L-7001|regulation of globulin G|regulation of peptidoglycan N-acetylmuramoylhydrolase activity|regulation of 1,4-N-acetylmuramidase activity http://purl.obolibrary.org/obo/GO_1903590 GO:0014844 biolink:BiologicalProcess myoblast proliferation involved in skeletal muscle regeneration The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014844 GO:0014843 biolink:BiologicalProcess growth factor dependent regulation of skeletal muscle satellite cell proliferation Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta. go-plus.json http://purl.obolibrary.org/obo/GO_0014843 GO:0014842 biolink:BiologicalProcess regulation of skeletal muscle satellite cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0014842 GO:0048192 biolink:MolecularActivity obsolete peptide antigen stabilization activity OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell. go-plus.json peptide antigen stabilization activity http://purl.obolibrary.org/obo/GO_0048192 UBERON:0001950 biolink:AnatomicalEntity neocortex An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN) go-plus.json neocortex (isocortex)|iso-cortex|nucleus hypoglossalis|nonolfactory cortex|homotypical cortex|neopallium|neopallial cortex|homogenetic cortex|isocortex|cerebral neocortex|isocortex (sensu lato) http://purl.obolibrary.org/obo/UBERON_0001950 GO:0000208 biolink:BiologicalProcess obsolete MAPK import into nucleus involved in osmosensory signaling pathway OBSOLETE. The directed movement of a MAP kinase to the nucleus during osmolarity sensing. go-plus.json MAPK import into nucleus involved in osmosensory signalling pathway|osmolarity sensing, MAPK import into nucleus|osmolarity sensing, nuclear translocation of MAPK|nuclear translocation of MAPK during osmolarity sensing|MAPK import into nucleus during osmolarity sensing|nuclear translocation of MAPK involved in osmosensory signalling pathway|nuclear translocation of MAPK involved in osmosensory signaling pathway http://purl.obolibrary.org/obo/GO_0000208 GO:0000207 biolink:BiologicalProcess obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces) OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). go-plus.json nuclear translocation of MAPK during sporulation (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000207 GO:0097119 biolink:BiologicalProcess postsynaptic density protein 95 clustering The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. go-plus.json PSD-95 clustering|post-synaptic density protein 95 clustering|Dlg4 clustering http://purl.obolibrary.org/obo/GO_0097119 GO:0048191 biolink:MolecularActivity obsolete peptide stabilization activity OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. go-plus.json peptide stabilization activity http://purl.obolibrary.org/obo/GO_0048191 OBO:uberon/core#transitively_connected_to biolink:OntologyClass transitively_connected to transitively_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to GO:0048190 biolink:BiologicalProcess wing disc dorsal/ventral pattern formation The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing. go-plus.json wing disc dorsal-ventral pattern formation|wing disc dorsoventral pattern formation http://purl.obolibrary.org/obo/GO_0048190 GO:0000206 biolink:BiologicalProcess obsolete inactivation of MAPK during sporulation (sensu Saccharomyces) OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). go-plus.json inactivation of MAPK during sporulation (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000206 GO:0000205 biolink:BiologicalProcess obsolete activation of MAPK during sporulation (sensu Saccharomyces) OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). go-plus.json activation of MAPK during sporulation (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000205 UBERON:0001951 biolink:AnatomicalEntity epithelium of nasopharynx An epithelium that is part of a nasopharynx [Automatically generated definition]. go-plus.json rhinopharynx epithelium|nasal part of pharynx epithelium|nasopharynx epithelium|epithelial tissue of rhinopharynx|epithelial tissue of nasopharynx|epithelium of nasal part of pharynx|epithelium of rhinopharynx|epithelial tissue of nasal part of pharynx|nasopharynx epithelial tissue|nasal part of pharynx epithelial tissue|rhinopharynx epithelial tissue|nasopharyngeal epithelium http://purl.obolibrary.org/obo/UBERON_0001951 GO:0097116 biolink:BiologicalProcess gephyrin clustering involved in postsynaptic density assembly The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses. go-plus.json Geph clustering http://purl.obolibrary.org/obo/GO_0097116 GO:0097115 biolink:BiologicalProcess neurexin clustering involved in presynaptic membrane assembly The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals. go-plus.json presynaptic neurexin clustering|neurexin clustering|Nrxn clustering http://purl.obolibrary.org/obo/GO_0097115 GO:0097118 biolink:BiologicalProcess neuroligin clustering involved in postsynaptic membrane assembly The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons. go-plus.json Nlgn clustering|postsynaptic neuroligin clustering|neuroligin clustering http://purl.obolibrary.org/obo/GO_0097118 GO:0000209 biolink:BiologicalProcess protein polyubiquitination Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. go-plus.json polyubiquitin|protein polyubiquitylation|protein polyubiquitinylation http://purl.obolibrary.org/obo/GO_0000209 GO:0097117 biolink:BiologicalProcess guanylate kinase-associated protein clustering The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons. go-plus.json GKAP clustering http://purl.obolibrary.org/obo/GO_0097117 GO:0000211 biolink:MolecularActivity obsolete protein degradation tagging activity OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction. go-plus.json protein degradation tagging activity http://purl.obolibrary.org/obo/GO_0000211 GO:0097123 biolink:CellularComponent cyclin A1-CDK2 complex A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097123 GO:0048199 biolink:BiologicalProcess vesicle targeting, to, from or within Golgi The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. go-plus.json Golgi vesicle targeting|dictyosome vesicle targeting|vesicle targeting, to, from or within dictyosome http://purl.obolibrary.org/obo/GO_0048199 GO:0000210 biolink:MolecularActivity NAD+ diphosphatase activity Catalysis of the reaction: NAD+ + H2O = AMP + NMN. RHEA:11800|EC:3.6.1.22|MetaCyc:NADPYROPHOSPHAT-RXN go-plus.json NAD pyrophosphatase activity|NAD diphosphatase activity|nicotinamide adenine dinucleotide pyrophosphatase activity|NAD(+) pyrophosphatase activity|NAD+ pyrophosphatase activity|NAD+ phosphohydrolase activity|NADH pyrophosphatase activity|NADP pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0000210 GO:0097122 biolink:CellularComponent cyclin A2-CDK1 complex A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097122 GO:0048198 biolink:BiologicalProcess Golgi vesicle bud deformation and release The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released. go-plus.json Golgi-derived vesicle bud deformation and release|dictyosome vesicle bud deformation http://purl.obolibrary.org/obo/GO_0048198 GO:0097125 biolink:CellularComponent cyclin B1-CDK1 complex A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097125 GO:0048197 biolink:BiologicalProcess Golgi membrane coat protein complex assembly The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat. go-plus.json dictyosome membrane binding by cytosolic coat proteins|Golgi membrane bud coat oligomerisation|dictyosome membrane bud coat oligomerisation http://purl.obolibrary.org/obo/GO_0048197 GO:0097124 biolink:CellularComponent cyclin A2-CDK2 complex A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097124 GO:0000215 biolink:MolecularActivity tRNA 2'-phosphotransferase activity Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate. RHEA:23324|MetaCyc:2.7.1.160-RXN|EC:2.7.1.160 go-plus.json 2'-phosphotransferase activity|2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity|yeast 2'-phosphotransferase activity|2'-phospho-tRNA:NAD+ phosphotransferase activity|Tpt1|Tpt1p http://purl.obolibrary.org/obo/GO_0000215 goslim_chembl GO:0048196 biolink:CellularComponent obsolete plant extracellular matrix OBSOLETE. The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella. go-plus.json plant extracellular matrix|middle lamella-containing extracellular matrix http://purl.obolibrary.org/obo/GO_0048196 GO:0000214 biolink:CellularComponent tRNA-intron endonuclease complex A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. go-plus.json tRNA splicing endonuclease complex|SEN complex http://purl.obolibrary.org/obo/GO_0000214 GO:0048195 biolink:BiologicalProcess Golgi membrane priming complex assembly The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex. go-plus.json formation of dictyosome membrane priming complex|formation of Golgi membrane priming complex http://purl.obolibrary.org/obo/GO_0048195 GO:0000213 biolink:MolecularActivity tRNA-intron endonuclease activity Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. MetaCyc:3.1.27.9-RXN|EC:3.1.27.9 go-plus.json splicing endonuclease activity|tRNA-splicing endonuclease activity|tRNA-intron endoribonuclease activity|transfer splicing endonuclease activity|transfer ribonucleate intron endoribonuclease activity|tRNA splicing endonuclease activity|tRNATRPintron endonuclease activity http://purl.obolibrary.org/obo/GO_0000213 GO:0048194 biolink:BiologicalProcess Golgi vesicle budding The evagination of the Golgi membrane, resulting in formation of a vesicle. go-plus.json dictyosome vesicle budding|Golgi-derived vesicle budding http://purl.obolibrary.org/obo/GO_0048194 GO:0097121 biolink:CellularComponent cyclin A1-CDK1 complex A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097121 GO:0048193 biolink:BiologicalProcess Golgi vesicle transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. go-plus.json Golgi-derived vesicle transport http://purl.obolibrary.org/obo/GO_0048193 goslim_yeast GO:0097120 biolink:BiologicalProcess receptor localization to synapse Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. go-plus.json receptor localisation to synapse http://purl.obolibrary.org/obo/GO_0097120 GO:0000212 biolink:BiologicalProcess meiotic spindle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. go-plus.json meiotic spindle organization and biogenesis|meiotic spindle organisation|meiotic spindle stabilization|spindle organization during meiosis http://purl.obolibrary.org/obo/GO_0000212 GO:0014859 biolink:BiologicalProcess negative regulation of skeletal muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0014859 GO:0014858 biolink:BiologicalProcess positive regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0014858 GO:0014857 biolink:BiologicalProcess regulation of skeletal muscle cell proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0014857 GO:1903599 biolink:BiologicalProcess positive regulation of autophagy of mitochondrion Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy. go-plus.json up regulation of mitochondrion degradation|activation of mitochondrion degradation|up-regulation of mitophagy|upregulation of mitophagy|up-regulation of mitochondrion degradation|up regulation of mitophagy|upregulation of mitochondrion degradation|positive regulation of mitochondrial degradation|activation of mitophagy http://purl.obolibrary.org/obo/GO_1903599 GO:1903598 biolink:BiologicalProcess positive regulation of gap junction assembly Any process that activates or increases the frequency, rate or extent of gap junction assembly. go-plus.json up-regulation of gap junction assembly|upregulation of gap junction assembly|up regulation of gap junction assembly|activation of gap junction assembly http://purl.obolibrary.org/obo/GO_1903598 GO:1903597 biolink:BiologicalProcess negative regulation of gap junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly. go-plus.json inhibition of gap junction assembly|down regulation of gap junction assembly|downregulation of gap junction assembly|down-regulation of gap junction assembly http://purl.obolibrary.org/obo/GO_1903597 GO:1903596 biolink:BiologicalProcess regulation of gap junction assembly Any process that modulates the frequency, rate or extent of gap junction assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1903596 GO:0014852 biolink:BiologicalProcess regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0014852 GO:0014850 biolink:BiologicalProcess response to muscle activity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0014850 GO:0014856 biolink:BiologicalProcess skeletal muscle cell proliferation The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0014856 GO:0014855 biolink:BiologicalProcess striated muscle cell proliferation The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0014855 GO:0014854 biolink:BiologicalProcess response to inactivity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0014854 GO:0014853 biolink:BiologicalProcess regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. go-plus.json regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0014853 GO:0000219 biolink:CellularComponent obsolete vacuolar hydrogen-transporting ATPase OBSOLETE. (Was not defined before being made obsolete). go-plus.json V-ATPase|vacuolar hydrogen-transporting ATPase http://purl.obolibrary.org/obo/GO_0000219 GO:0000218 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000218 CHEBI:38373 biolink:ChemicalSubstance 3-dodecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38373 GO:0000217 biolink:MolecularActivity DNA secondary structure binding Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction. go-plus.json http://purl.obolibrary.org/obo/GO_0000217 GO:0000216 biolink:BiologicalProcess obsolete M/G1 transition of mitotic cell cycle OBSOLETE. Progression from M phase to G1 phase of the mitotic cell cycle. go-plus.json M/G1 transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000216 CHEBI:38371 biolink:ChemicalSubstance 2-dodecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38371 GO:0097127 biolink:CellularComponent cyclin B3-CDK2 complex A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097127 GO:0097126 biolink:CellularComponent cyclin B2-CDK1 complex A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097126 GO:0097129 biolink:CellularComponent cyclin D2-CDK4 complex A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097129 GO:0097128 biolink:CellularComponent cyclin D1-CDK4 complex A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097128 UBERON:0001926 biolink:AnatomicalEntity lateral geniculate body the group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe go-plus.json corpus geniculatum laterales|external geniculate body|corpus geniculatus lateralis|corpus geniculatum laterale|lateral geniculate nucleus|nucleus corporis geniculati lateralis|lateral geniculate complex|LGN|nucleus geniculatus lateralis|LGB|corpus geniculatum externum http://purl.obolibrary.org/obo/UBERON_0001926 GO:0014827 biolink:BiologicalProcess intestine smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0014827 GO:0014826 biolink:BiologicalProcess vein smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds. go-plus.json http://purl.obolibrary.org/obo/GO_0014826 GO:0014825 biolink:BiologicalProcess stomach fundus smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch. go-plus.json http://purl.obolibrary.org/obo/GO_0014825 GO:0014824 biolink:BiologicalProcess artery smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0014824 GO:0014829 biolink:BiologicalProcess vascular associated smooth muscle contraction A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion. go-plus.json vascular smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014829 GO:0014828 biolink:BiologicalProcess distal stomach smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus. go-plus.json http://purl.obolibrary.org/obo/GO_0014828 GO:0014823 biolink:BiologicalProcess response to activity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus. go-plus.json response to exercise http://purl.obolibrary.org/obo/GO_0014823 GO:0014822 biolink:BiologicalProcess detection of wounding The series of events by which an injury stimulus is received and converted into a molecular signal. go-plus.json detection of injury http://purl.obolibrary.org/obo/GO_0014822 GO:0014821 biolink:BiologicalProcess phasic smooth muscle contraction A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. go-plus.json http://purl.obolibrary.org/obo/GO_0014821 GO:0014820 biolink:BiologicalProcess tonic smooth muscle contraction A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014820 CHEBI:38340 biolink:ChemicalSubstance hydroxypyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38340 CHEBI:38342 biolink:ChemicalSubstance L-sorbose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38342 GO:0097101 biolink:BiologicalProcess blood vessel endothelial cell fate specification The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0097101 UBERON:0001913 biolink:AnatomicalEntity milk An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation. go-plus.json mammary gland milk http://purl.obolibrary.org/obo/UBERON_0001913 GO:0097100 biolink:MolecularActivity supercoiled DNA binding Binding to supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0097100 GO:0097103 biolink:BiologicalProcess endothelial stalk cell fate specification The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout. go-plus.json angiogenic stalk cell fate specification http://purl.obolibrary.org/obo/GO_0097103 UBERON:0001916 biolink:AnatomicalEntity endothelium of arteriole An endothelium that is part of an arteriole [Automatically generated definition]. go-plus.json arteriole endothelium http://purl.obolibrary.org/obo/UBERON_0001916 GO:0097102 biolink:BiologicalProcess endothelial tip cell fate specification The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. go-plus.json angiogenic tip cell fate specification http://purl.obolibrary.org/obo/GO_0097102 UBERON:0001915 biolink:AnatomicalEntity endothelium of capillary An endothelium that is part of a capillary [Automatically generated definition]. go-plus.json capillary endothelium|endothelium of capillary vessel|blood capillary endothelium|capillary vessel endothelium|endothelium of blood capillary http://purl.obolibrary.org/obo/UBERON_0001915 UBERON:0001912 biolink:AnatomicalEntity lobule of mammary gland Organ component of the mammary gland which consists of an aggregate of mammary alveoli that communicate with a lobular lactiferous duct.[FMA] go-plus.json mammary gland lobule|lactiferous acinus|lactiferous gland lobule|acinus of mammary gland|lobule of lactiferous gland|lactiferous lobule|mammary acinus|lobule of mammary gland http://purl.obolibrary.org/obo/UBERON_0001912 UBERON:0001911 biolink:AnatomicalEntity mammary gland A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males. go-plus.json milk patch|mamma|glandula mammaria|lobe of breast|glandula mammaria|mammae|lobe of mammary gland|Brustdruese|dug|lactiferous gland http://purl.obolibrary.org/obo/UBERON_0001911 GO:0014838 biolink:BiologicalProcess myoblast fate specification involved in skeletal muscle regeneration The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014838 GO:0014837 biolink:BiologicalProcess myoblast fate determination involved in skeletal muscle regeneration The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014837 GO:0014836 biolink:BiologicalProcess myoblast fate commitment involved in skeletal muscle regeneration The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014836 GO:0014835 biolink:BiologicalProcess myoblast differentiation involved in skeletal muscle regeneration The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014835 UBERON:0001918 biolink:AnatomicalEntity endothelium of venule An endothelium that is part of a venule [Automatically generated definition]. go-plus.json venule endothelium http://purl.obolibrary.org/obo/UBERON_0001918 UBERON:0001917 biolink:AnatomicalEntity endothelium of artery An endothelium that is part of an artery [Automatically generated definition]. go-plus.json artery endothelium|arterial endothelium http://purl.obolibrary.org/obo/UBERON_0001917 UBERON:0001919 biolink:AnatomicalEntity endothelium of vein An endothelium that is part of a vein [Automatically generated definition]. go-plus.json vein endothelium|veinous endothelium|venous endothelium http://purl.obolibrary.org/obo/UBERON_0001919 GO:0014839 biolink:BiologicalProcess myoblast migration involved in skeletal muscle regeneration The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json mononucleate cell migration involved in skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0014839 GO:0014830 biolink:BiologicalProcess arteriole smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries. go-plus.json http://purl.obolibrary.org/obo/GO_0014830 CHEBI:38358 biolink:ChemicalSubstance (2E,4E)-hexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38358 GO:0014834 biolink:BiologicalProcess skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells. go-plus.json satellite cell self-renewal|satellite cell compartment self-renewal involved in skeletal muscle regeneration|satellite cell population maintenance http://purl.obolibrary.org/obo/GO_0014834 GO:0014833 biolink:BiologicalProcess skeletal muscle satellite stem cell asymmetric division The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool. go-plus.json satellite cell asymmetric division http://purl.obolibrary.org/obo/GO_0014833 GO:0014832 biolink:BiologicalProcess urinary bladder smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. go-plus.json http://purl.obolibrary.org/obo/GO_0014832 GO:0014831 biolink:BiologicalProcess gastro-intestinal system smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). go-plus.json http://purl.obolibrary.org/obo/GO_0014831 GO:0097109 biolink:MolecularActivity neuroligin family protein binding Binding to a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation. go-plus.json http://purl.obolibrary.org/obo/GO_0097109 GO:0097108 biolink:MolecularActivity hedgehog family protein binding Binding to a member of the hedgehog protein family, signaling proteins involved in development. go-plus.json http://purl.obolibrary.org/obo/GO_0097108 GO:0097105 biolink:BiologicalProcess presynaptic membrane assembly The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction. go-plus.json pre-synaptic membrane assembly http://purl.obolibrary.org/obo/GO_0097105 goslim_synapse CHEBI:38356 biolink:ChemicalSubstance trans-hex-4-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38356 GO:0097104 biolink:BiologicalProcess postsynaptic membrane assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). go-plus.json post-synaptic membrane assembly http://purl.obolibrary.org/obo/GO_0097104 goslim_synapse CHEBI:38355 biolink:ChemicalSubstance hex-4-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38355 GO:0097107 biolink:BiologicalProcess postsynaptic density assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. go-plus.json post synaptic density assembly|PSD assembly|post-synaptic density assembly http://purl.obolibrary.org/obo/GO_0097107 goslim_synapse GO:0097106 biolink:BiologicalProcess postsynaptic density organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. go-plus.json PSD organization|post-synaptic density organization|postsynaptic density organisation|post synaptic density organization http://purl.obolibrary.org/obo/GO_0097106 GO:0097156 biolink:BiologicalProcess fasciculation of motor neuron axon The collection of motor neuron axons into a bundle of rods, known as a fascicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097156 GO:0097155 biolink:BiologicalProcess fasciculation of sensory neuron axon The collection of sensory neuron axons into a bundle of rods, known as a fascicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097155 GO:0097158 biolink:MolecularActivity pre-mRNA intronic pyrimidine-rich binding Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA). go-plus.json pre-messenger RNA intronic pyrimidine-rich binding http://purl.obolibrary.org/obo/GO_0097158 GO:0097157 biolink:MolecularActivity pre-mRNA intronic binding Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA). go-plus.json pre-messenger RNA intronic binding http://purl.obolibrary.org/obo/GO_0097157 UBERON:0001987 biolink:AnatomicalEntity placenta organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. go-plus.json allantoic placenta|eutherian placenta http://purl.obolibrary.org/obo/UBERON_0001987 GO:0097152 biolink:BiologicalProcess mesenchymal cell apoptotic process Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. go-plus.json mesenchymal cell apoptosis http://purl.obolibrary.org/obo/GO_0097152 UBERON:0001986 biolink:AnatomicalEntity endothelium A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0001986 GO:0097151 biolink:BiologicalProcess positive regulation of inhibitory postsynaptic potential Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. go-plus.json positive regulation of inhibitory post-synaptic membrane potential|positive regulation of IPSP http://purl.obolibrary.org/obo/GO_0097151 GO:0097154 biolink:BiologicalProcess GABAergic neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0097154 UBERON:0001988 biolink:AnatomicalEntity feces Portion of semisolid bodily waste discharged through the anus[MW,modified] go-plus.json fecal matter|portion of excrement|spoor|dung|droppings|stool|portion of guano|fewmet|spraint|scat|portion of fecal material|faeces|portionem cacas|excreta|cow dung|ordure|portion of feces|portion of fecal matter|portion of dung|excrement|frass|guano|portion of scat|fecal material|portion of faeces|piece of shit|cow pat http://purl.obolibrary.org/obo/UBERON_0001988 GO:0097153 biolink:MolecularActivity cysteine-type endopeptidase activity involved in apoptotic process Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process. Reactome:R-HSA-6800797 go-plus.json caspase activity|metacaspase activity http://purl.obolibrary.org/obo/GO_0097153 GO:0014805 biolink:BiologicalProcess smooth muscle adaptation Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. go-plus.json smooth muscle plasticity http://purl.obolibrary.org/obo/GO_0014805 GO:0014804 biolink:CellularComponent terminal cisterna lumen The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin. go-plus.json http://purl.obolibrary.org/obo/GO_0014804 GO:0014803 biolink:CellularComponent longitudinal sarcoplasmic reticulum lumen The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae. go-plus.json http://purl.obolibrary.org/obo/GO_0014803 GO:0097150 biolink:BiologicalProcess neuronal stem cell population maintenance Any process in by an organism or tissue maintains a population of neuronal stem cells. go-plus.json http://purl.obolibrary.org/obo/GO_0097150 GO:0014802 biolink:CellularComponent terminal cisterna The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release. Wikipedia:Terminal_cisterna go-plus.json http://purl.obolibrary.org/obo/GO_0014802 GO:0014809 biolink:BiologicalProcess regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. go-plus.json http://purl.obolibrary.org/obo/GO_0014809 GO:0014808 biolink:BiologicalProcess release of sequestered calcium ion into cytosol by sarcoplasmic reticulum The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels. go-plus.json release of sequestered calcium ion by sarcoplasmic reticulum into cytosol http://purl.obolibrary.org/obo/GO_0014808 GO:0014807 biolink:BiologicalProcess regulation of somitogenesis Any process that modulates the frequency, rate or extent of somitogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0014807 GO:0014806 biolink:BiologicalProcess smooth muscle hyperplasia A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ. go-plus.json http://purl.obolibrary.org/obo/GO_0014806 CHEBI:38326 biolink:ChemicalSubstance thiazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38326 CHEBI:38325 biolink:ChemicalSubstance muscarinic agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_38325 CHEBI:38324 biolink:ChemicalSubstance cholinergic agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_38324 GO:0014801 biolink:CellularComponent longitudinal sarcoplasmic reticulum The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae. go-plus.json http://purl.obolibrary.org/obo/GO_0014801 CHEBI:38329 biolink:ChemicalSubstance oxazolidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38329 UBERON:0001994 biolink:AnatomicalEntity hyaline cartilage tissue Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance. go-plus.json chondroid cartilage|hyaline cartilage http://purl.obolibrary.org/obo/UBERON_0001994 UBERON:0001996 biolink:AnatomicalEntity elastic cartilage tissue Cartilage tissue that is flexible and contains abundant elastic fibers. go-plus.json yellow elastic cartilage tissue|reticular cartilage|elastic cartilage tissue|elastic cartilage|yellow cartilage|yellow elastic cartilage http://purl.obolibrary.org/obo/UBERON_0001996 UBERON:0001995 biolink:AnatomicalEntity fibrocartilage Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns. go-plus.json fibrocartilage tissue|stratified cartilage tissue http://purl.obolibrary.org/obo/UBERON_0001995 CHEBI:38323 biolink:ChemicalSubstance cholinergic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_38323 GO:0097159 biolink:MolecularActivity organic cyclic compound binding Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. go-plus.json http://purl.obolibrary.org/obo/GO_0097159 CHEBI:38320 biolink:ChemicalSubstance (+)-usnic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38320 GO:0097167 biolink:BiologicalProcess circadian regulation of translation Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours. go-plus.json regulation of mRNA translation in response to circadian clock http://purl.obolibrary.org/obo/GO_0097167 UBERON:0001979 biolink:AnatomicalEntity venule One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins go-plus.json venula http://purl.obolibrary.org/obo/UBERON_0001979 GO:0097166 biolink:BiologicalProcess lens epithelial cell proliferation The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. go-plus.json http://purl.obolibrary.org/obo/GO_0097166 GO:0097169 biolink:CellularComponent AIM2 inflammasome complex An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0097169 GO:0097168 biolink:BiologicalProcess mesenchymal stem cell proliferation The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json MSC proliferation http://purl.obolibrary.org/obo/GO_0097168 GO:0097163 biolink:MolecularActivity sulfur carrier activity Covalently binding to sulfur and delivering it to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0097163 UBERON:0001976 biolink:AnatomicalEntity epithelium of esophagus the epithelial layer that lines the luminal space of the esophagus go-plus.json epithelial tissue of oesophagus|epithelium of oesophagus|oesophagus epithelial tissue|esophageal epithelium|oesophagus epithelium|epithelial tissue of gullet|epithelium of gullet|gullet epithelium|esophagus epithelium|epithelial tissue of esophagus|gullet epithelial tissue|esophagus epithelial tissue http://purl.obolibrary.org/obo/UBERON_0001976 UBERON:0001975 biolink:AnatomicalEntity serosa of esophagus A serous membrane that is part of a esophagus [Automatically generated definition]. go-plus.json gullet serous membrane|esophagus serous membrane|serosa of gullet|esophagus serosa|gullet serosa|serous membrane of oesophagus|tunica serosa oesophageae|oesophagus serous membrane|serosa of oesophagus|serous membrane of esophagus|serosa of abdominal part of esophagus|serous membrane of gullet|oesophagus serosa|serous coat of oesophagus http://purl.obolibrary.org/obo/UBERON_0001975 GO:0097162 biolink:MolecularActivity MADS box domain binding Binding to a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs. go-plus.json http://purl.obolibrary.org/obo/GO_0097162 GO:0097165 biolink:CellularComponent nuclear stress granule A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress. go-plus.json http://purl.obolibrary.org/obo/GO_0097165 UBERON:0001978 biolink:AnatomicalEntity parenchyma of pancreas go-plus.json pancreatic parenchyma|pancreas parenchyma http://purl.obolibrary.org/obo/UBERON_0001978 GO:0097164 biolink:BiologicalProcess ammonium ion metabolic process The chemical reactions and pathways involving the ammonium ion. go-plus.json ammonium ion metabolism|ammonium metabolic process http://purl.obolibrary.org/obo/GO_0097164 GO:0014816 biolink:BiologicalProcess skeletal muscle satellite cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a satellite cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014816 GO:0014815 biolink:BiologicalProcess initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. go-plus.json http://purl.obolibrary.org/obo/GO_0014815 GO:0097161 biolink:MolecularActivity DH domain binding Binding to a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket. go-plus.json http://purl.obolibrary.org/obo/GO_0097161 GO:0014814 biolink:BiologicalProcess axon regeneration at neuromuscular junction The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones. go-plus.json http://purl.obolibrary.org/obo/GO_0014814 GO:0097160 biolink:MolecularActivity polychlorinated biphenyl binding Binding to a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings. go-plus.json PCB binding|polychlorobiphenyl binding http://purl.obolibrary.org/obo/GO_0097160 GO:0014813 biolink:BiologicalProcess skeletal muscle satellite cell commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014813 GO:0014819 biolink:BiologicalProcess regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014819 GO:0014818 biolink:BiologicalProcess skeletal muscle satellite cell fate determination The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0014818 UBERON:0011300 biolink:AnatomicalEntity gray matter of telencephalon A portion of gray matter that is part of a telencephalon. go-plus.json predominantly gray regional part of telencephalon http://purl.obolibrary.org/obo/UBERON_0011300 GO:0014817 biolink:BiologicalProcess skeletal muscle satellite cell fate specification The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0014817 CHEBI:38338 biolink:ChemicalSubstance aminopyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38338 CHEBI:38337 biolink:ChemicalSubstance pyrimidone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38337 CHEBI:38336 biolink:ChemicalSubstance dithiolanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38336 CHEBI:38335 biolink:ChemicalSubstance dithiolane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38335 GO:0014812 biolink:BiologicalProcess muscle cell migration The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0014812 GO:0014811 biolink:BiologicalProcess negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. go-plus.json http://purl.obolibrary.org/obo/GO_0014811 GO:0014810 biolink:BiologicalProcess positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. go-plus.json http://purl.obolibrary.org/obo/GO_0014810 CHEBI:38339 biolink:ChemicalSubstance formamidopyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38339 UBERON:0001982 biolink:AnatomicalEntity capillary Any of the smallest blood vessels connecting arterioles with venules. go-plus.json blood capillary|capillary vessel http://purl.obolibrary.org/obo/UBERON_0001982 UBERON:0001985 biolink:AnatomicalEntity corneal endothelium A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]. go-plus.json endothelium of cornea|epithelium posterius corneae|cornea endothelium http://purl.obolibrary.org/obo/UBERON_0001985 CHEBI:38333 biolink:ChemicalSubstance thiazolidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38333 UBERON:0001981 biolink:AnatomicalEntity blood vessel A vessel through which blood circulates in the body. go-plus.json region of vascular tree organ|vascular tree organ region|vas sanguineum|vascular element http://purl.obolibrary.org/obo/UBERON_0001981 CHEBI:38332 biolink:ChemicalSubstance pyrancarbaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_38332 UBERON:0001980 biolink:AnatomicalEntity arteriole The smallest division of the artery located between the muscular arteries and the capillaries[GO]. go-plus.json arteriola http://purl.obolibrary.org/obo/UBERON_0001980 CHEBI:38331 biolink:ChemicalSubstance 11-tetradecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38331 UBERON:0001969 biolink:AnatomicalEntity blood plasma The liquid component of blood, in which erythrocytes are suspended. go-plus.json plasma|portion of plasma|blood plasm|portion of blood plasma http://purl.obolibrary.org/obo/UBERON_0001969 GO:0097134 biolink:CellularComponent cyclin E1-CDK2 complex A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097134 GO:0097133 biolink:CellularComponent cyclin D3-CDK6 complex A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097133 UBERON:0001968 biolink:AnatomicalEntity semen Organism substance that is composed of sperm cells suspended in seminal fluid. go-plus.json ejaculate|sperm http://purl.obolibrary.org/obo/UBERON_0001968 CHEBI:28989 biolink:ChemicalSubstance 2,4,5-trichlorocyclohexa-2,5-dien-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28989 chebi_ph7_3 GO:0097136 biolink:CellularComponent Bcl-2 family protein complex A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed. go-plus.json http://purl.obolibrary.org/obo/GO_0097136 GO:0097135 biolink:CellularComponent cyclin E2-CDK2 complex A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097135 GO:0097130 biolink:CellularComponent cyclin D3-CDK4 complex A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097130 CHEBI:28985 biolink:ChemicalSubstance (R)-1,2-epoxypropane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28985 chebi_ph7_3 GO:0097132 biolink:CellularComponent cyclin D2-CDK6 complex A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097132 GO:0097131 biolink:CellularComponent cyclin D1-CDK6 complex A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. go-plus.json http://purl.obolibrary.org/obo/GO_0097131 CHEBI:28987 biolink:ChemicalSubstance abietic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28987 CHEBI:28982 biolink:ChemicalSubstance (S)-1,2-epoxypropane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28982 chebi_ph7_3 CHEBI:28984 biolink:ChemicalSubstance aluminium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_28984 chebi_ph7_3 CHEBI:38305 biolink:ChemicalSubstance gibberellin monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38305 CHEBI:38304 biolink:ChemicalSubstance diazolidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38304 CHEBI:38303 biolink:ChemicalSubstance azirinopyrroloindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38303 CHEBI:38308 biolink:ChemicalSubstance N-acylimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38308 CHEBI:38307 biolink:ChemicalSubstance imidazolyl carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38307 CHEBI:38306 biolink:ChemicalSubstance imidazole-4-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38306 UBERON:0001972 biolink:AnatomicalEntity submucosa of esophagus A submucosa that is part of a esophagus [Automatically generated definition]. go-plus.json tela submucosa esophagi|tela submucosa oesophageae|esophagus submucosa|gullet submucosa|tela submucosa oesophagi|submucosa of oesophagus|esophageal submucosa|submucosa of esophagus|oesophagus submucosa|submucous layer of esophagus|tela submucosa of esophagus|tela submucosa (oesophagus)|submucosa of gullet http://purl.obolibrary.org/obo/UBERON_0001972 UBERON:0001971 biolink:AnatomicalEntity gastric juice . go-plus.json stomach secretion|succus gastricus http://purl.obolibrary.org/obo/UBERON_0001971 UBERON:0001974 biolink:AnatomicalEntity lamina propria of esophagus A lamina propria that is part of a esophagus [Automatically generated definition]. go-plus.json lamina propria of oesophagus|oesophagus lamina propria mucosae|lamina propria mucosa of gullet|lamina propria mucosa of esophagus|oesophagus lamina propria|esophageal lamina propria|gullet lamina propria mucosa|lamina propria mucosae of gullet|esophagus lamina propria mucosa|esophagus lamina propria mucosae|gullet lamina propria mucosae|lamina propria of gullet|lamina propria mucosa of oesophagus|gullet lamina propria|esophagus lamina propria|lamina propria mucosae of esophagus|lamina propria mucosae of oesophagus|oesophagus lamina propria mucosa http://purl.obolibrary.org/obo/UBERON_0001974 GO:0097138 biolink:CellularComponent BAD-BCL-2 complex A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097138 GO:0097137 biolink:CellularComponent BAD-BCL-xl complex A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097137 UBERON:0001970 biolink:AnatomicalEntity bile vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium. go-plus.json gall|fel http://purl.obolibrary.org/obo/UBERON_0001970 GO:0097139 biolink:CellularComponent BID-BCL-2 complex A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097139 UBERON:0001958 biolink:AnatomicalEntity terminal bronchiole epithelium An epithelium that lines a terminal bronchiole. go-plus.json epithelium of bronchiolus terminalis|epithelium of terminal bronchiole|epithelial tissue of terminal bronchiole|terminal bronchiole epithelial tissue|bronchiolus terminalis epithelial tissue|bronchiolus terminalis epithelium|terminal bronchiole epithelium|epithelial tissue of bronchiolus terminalis http://purl.obolibrary.org/obo/UBERON_0001958 GO:0097145 biolink:CellularComponent BAK complex An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097145 UBERON:0001957 biolink:AnatomicalEntity submucosa of bronchus A submucosa that is part of a bronchus [Automatically generated definition]. go-plus.json submucous layer of bronchi|bronchial submucosa|tela submucosa bronchi|bronchi submucosa|bronchial trunk submucosa|bronchus submucosa|submucosa of bronchi|submucosa of bronchial trunk http://purl.obolibrary.org/obo/UBERON_0001957 GO:0097144 biolink:CellularComponent BAX complex An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097144 GO:0097147 biolink:CellularComponent NOXA-BCL-2 complex A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097147 GO:0097146 biolink:CellularComponent NOXA-BCL-xl complex A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097146 UBERON:0001959 biolink:AnatomicalEntity white pulp of spleen the parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies go-plus.json spleen white pulp|white pulp|pulpa alba|splenic white pulp|noduli lymphoidei splenici http://purl.obolibrary.org/obo/UBERON_0001959 UBERON:0001954 biolink:AnatomicalEntity Ammon's horn A part of the brain consisting of a three layered cortex located in the forebrain bordering the medial surface of the lateral ventricle. The term hippocampus is often used synonymously with hippocampal formation which consists of the hippocampus proper or Cornu Ammonis, the dentate gyrus and the subiculum. go-plus.json hippocampus major|ammon horn|hippocampus proper|ammon gyrus|Ammon's horn|cornu ammonis|Ammon horn fields|Ammons horn|hippocampus proprius|hippocampus http://purl.obolibrary.org/obo/UBERON_0001954 GO:0097141 biolink:CellularComponent BIM-BCL-2 complex A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097141 CHEBI:28997 biolink:ChemicalSubstance 2'-deoxyinosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28997 chebi_ph7_3 GO:0097140 biolink:CellularComponent BIM-BCL-xl complex A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097140 CHEBI:28999 biolink:ChemicalSubstance N-acetyl-9-O-acetylneuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28999 chebi_ph7_3 GO:0097143 biolink:CellularComponent PUMA-BCL-xl complex A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097143 UBERON:0001956 biolink:AnatomicalEntity cartilage of bronchus The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]. go-plus.json bronchial cartilage|bronchial cartilage ring|bronchi cartilage|bronchial trunk cartilage|cartilage of bronchi|cartilage of bronchial trunk|bronchus cartilage|cartilagines bronchiales http://purl.obolibrary.org/obo/UBERON_0001956 GO:0097142 biolink:CellularComponent PUMA-BCL-2 complex A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097142 CHEBI:28992 biolink:ChemicalSubstance 2-hydroxychromene-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28992 CHEBI:28995 biolink:ChemicalSubstance 2,4-dichlorobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28995 chebi_ph7_3 CHEBI:28991 biolink:ChemicalSubstance (2S,3R)-aldono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28991 chebi_ph7_3 CHEBI:28990 biolink:ChemicalSubstance 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28990 CHEBI:38316 biolink:ChemicalSubstance pyrimidinecarboxylate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38316 CHEBI:38315 biolink:ChemicalSubstance beta-D-arabinoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_38315 CHEBI:38314 biolink:ChemicalSubstance pyrazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38314 CHEBI:38313 biolink:ChemicalSubstance diazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38313 CHEBI:38319 biolink:ChemicalSubstance usnic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38319 CHEBI:38317 biolink:ChemicalSubstance EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38317 UBERON:0001961 biolink:AnatomicalEntity mucosa-associated lymphoid tissue diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin[WP]. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes[GO]. go-plus.json epithelio-lymphoid tissue|mucosa-associated lymphoid tissue|MALT|mucosal-associated lymphoid tissue|mucosa associated lymphatic tissue|mucosa associated lymphoid tissue|mucosal-associated lymphatic tissue http://purl.obolibrary.org/obo/UBERON_0001961 UBERON:0001960 biolink:AnatomicalEntity periarterial lymphatic sheath The area of the spleen in which T cells surround the central arteriole go-plus.json periarteriolar sheath|splenic periarteriolar lymphoid sheath|spleen periarteriolar lymphatic sheath|periarterial lymphoid sheath|T cell domain of the splenic white pulp|PALS http://purl.obolibrary.org/obo/UBERON_0001960 UBERON:0001963 biolink:AnatomicalEntity bronchial-associated lymphoid tissue A diffuse collection of lymphpoid cells that participate in airway immune responses go-plus.json bronchus associated lymphoid tissue|BALT http://purl.obolibrary.org/obo/UBERON_0001963 UBERON:0001962 biolink:AnatomicalEntity gut-associated lymphoid tissue Mucosa-associated lymphoid tissue in digestive tract. includes Peyer's patches, appendix, and solitary lymph nodules[GO]. go-plus.json gut associated lymphoid tissue|GALT http://purl.obolibrary.org/obo/UBERON_0001962 GO:0097149 biolink:CellularComponent centralspindlin complex A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals). go-plus.json http://purl.obolibrary.org/obo/GO_0097149 GO:0097148 biolink:CellularComponent BCL-2 complex A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators. go-plus.json http://purl.obolibrary.org/obo/GO_0097148 CHEBI:38311 biolink:ChemicalSubstance cephem go-plus.json http://purl.obolibrary.org/obo/CHEBI_38311 GO:0048101 biolink:MolecularActivity calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive. go-plus.json calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity|calcium- and calmodulin-regulated cGMP phosphodiesterase activity|calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity|calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0048101 GO:0000167 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000167 GO:0048100 biolink:BiologicalProcess wing disc anterior/posterior pattern formation The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing. go-plus.json http://purl.obolibrary.org/obo/GO_0048100 GO:0000166 biolink:MolecularActivity nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0000166 goslim_pir|goslim_plant|goslim_metagenomics|goslim_chembl GO:0000165 biolink:BiologicalProcess MAPK cascade An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. Wikipedia:MAPK_cascade|Wikipedia:Mitogen-activated_protein_kinase go-plus.json MAPK signalling|mitogen-activated protein kinase cascade|MAPK signaling|MAPKKK cascade|MAPKKK cascade during sporulation|MAP kinase cascade|MAP kinase kinase kinase cascade|MAPK signal transduction|ERK/MAPK cascade http://purl.obolibrary.org/obo/GO_0000165 GO:0000164 biolink:CellularComponent protein phosphatase type 1 complex A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity. go-plus.json http://purl.obolibrary.org/obo/GO_0000164 GO:1903509 biolink:BiologicalProcess liposaccharide metabolic process The chemical reactions and pathways involving liposaccharide. go-plus.json liposaccharide metabolism http://purl.obolibrary.org/obo/GO_1903509 GO:1903508 biolink:BiologicalProcess positive regulation of nucleic acid-templated transcription Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription. go-plus.json activation of nucleic acid-templated transcription|up-regulation of nucleic acid-templated transcription|up regulation of nucleic acid-templated transcription|upregulation of nucleic acid-templated transcription http://purl.obolibrary.org/obo/GO_1903508 CHEBI:87260 biolink:ChemicalSubstance O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87260 GO:1903507 biolink:BiologicalProcess negative regulation of nucleic acid-templated transcription Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription. go-plus.json down-regulation of nucleic acid-templated transcription|downregulation of nucleic acid-templated transcription|down regulation of nucleic acid-templated transcription|inhibition of nucleic acid-templated transcription http://purl.obolibrary.org/obo/GO_1903507 GO:1903506 biolink:BiologicalProcess regulation of nucleic acid-templated transcription Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription. go-plus.json http://purl.obolibrary.org/obo/GO_1903506 GO:0000169 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000169 GO:1903505 biolink:BiologicalProcess regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle Any process that modulates the frequency, rate or extent of establishment of actomyosin contractile ring localization involved in mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1903505 GO:0000168 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000168 GO:0048109 biolink:BiologicalProcess peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water. RESID:AA0344 go-plus.json http://purl.obolibrary.org/obo/GO_0048109 GO:1903504 biolink:BiologicalProcess regulation of mitotic spindle checkpoint Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint. go-plus.json regulation of mitotic cell cycle spindle checkpoint http://purl.obolibrary.org/obo/GO_1903504 gocheck_do_not_manually_annotate CL:0011027 biolink:Cell skeletal muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. go-plus.json skeleton muscle fibroblast http://purl.obolibrary.org/obo/CL_0011027 GO:0048108 biolink:BiologicalProcess peptide cross-linking via 4-amino-3-isothiazolidinone The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue. go-plus.json http://purl.obolibrary.org/obo/GO_0048108 GO:1903503 biolink:CellularComponent ATPase inhibitor complex A protein complex which is capable of ATPase inhibitor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903503 CL:0011026 biolink:Cell progenitor cell A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. go-plus.json http://purl.obolibrary.org/obo/CL_0011026 GO:1903502 biolink:CellularComponent translation repressor complex A protein complex which is capable of translation repressor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903502 GO:0048107 biolink:BiologicalProcess 4-amino-3-isothiazolidinone biosynthetic process The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively. go-plus.json 4-amino-3-isothiazolidinone synthesis|4-amino-3-isothiazolidinone formation|4-amino-3-isothiazolidinone biosynthesis|4-amino-3-isothiazolidinone anabolism http://purl.obolibrary.org/obo/GO_0048107 GO:1903501 biolink:BiologicalProcess positive regulation of mitotic actomyosin contractile ring assembly Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly. go-plus.json upregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|upregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of contractile ring assembly involved in mitotic cytokinesis|activation of contractile ring assembly involved in mitotic cytokinesis|up regulation of mitotic actomyosin contractile ring assembly|positive regulation of contractile ring assembly involved in mitotic cytokinesis|up regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|activation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|activation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|positive regulation of mitotic cytokinesis, actomyosin contractile ring assembly|upregulation of mitotic actomyosin contractile ring assembly|up-regulation of contractile ring assembly involved in mitotic cytokinesis|up-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|activation of mitotic actomyosin contractile ring assembly|up-regulation of mitotic actomyosin contractile ring assembly|upregulation of contractile ring assembly involved in mitotic cytokinesis http://purl.obolibrary.org/obo/GO_1903501 GO:0048106 biolink:BiologicalProcess establishment of thoracic bristle planar orientation Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction. go-plus.json establishment of body bristle planar orientation http://purl.obolibrary.org/obo/GO_0048106 CL:0011024 biolink:Cell double negative T regulatory cell A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation. go-plus.json double-negative alpha-beta regulatory T cell|CD4-negative, CD8-negative, alpha-beta regulatory T cells|DN Treg http://purl.obolibrary.org/obo/CL_0011024 GO:1903500 biolink:BiologicalProcess negative regulation of mitotic actomyosin contractile ring assembly Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly. go-plus.json down regulation of contractile ring assembly involved in mitotic cytokinesis|down regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down-regulation of mitotic actomyosin contractile ring assembly|inhibition of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of contractile ring assembly involved in mitotic cytokinesis|downregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of mitotic actomyosin contractile ring assembly|down-regulation of contractile ring assembly involved in mitotic cytokinesis|negative regulation of contractile ring assembly involved in mitotic cytokinesis|down regulation of mitotic actomyosin contractile ring assembly|down-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|negative regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|inhibition of mitotic actomyosin contractile ring assembly|negative regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|inhibition of contractile ring assembly involved in mitotic cytokinesis|down-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|negative regulation of mitotic cytokinesis, actomyosin contractile ring assembly|inhibition of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis http://purl.obolibrary.org/obo/GO_1903500 GO:0048105 biolink:BiologicalProcess establishment of body hair planar orientation Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface. go-plus.json http://purl.obolibrary.org/obo/GO_0048105 GO:0000163 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000163 GO:0000162 biolink:BiologicalProcess tryptophan biosynthetic process The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate. MetaCyc:TRPSYN-PWY go-plus.json tryptophan anabolism|tryptophan synthesis|tryptophan formation|aromatic amino acid family biosynthetic process, anthranilate pathway|tryptophan biosynthesis http://purl.obolibrary.org/obo/GO_0000162 GO:0048104 biolink:BiologicalProcess establishment of body hair or bristle planar orientation Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project. go-plus.json http://purl.obolibrary.org/obo/GO_0048104 GO:0000161 biolink:BiologicalProcess osmosensory signaling MAPK cascade A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K. go-plus.json osmolarity sensing, activation of MAP kinase kinase activity|osmolarity sensing, activation of MAPKK activity|MAPKKK cascade involved in osmosensory signalling pathway|activation of MAPKKK activity during osmolarity sensing|Hog1/Sty1 stress-activated MAPK cascade|MAPKKK cascade during osmolarity sensing|activation of MAPK activity involved in osmosensory signaling pathway|activation of MAPKKK activity involved in osmosensory signaling pathway|MAPK cascade involved in osmosensory signaling pathway|inactivation of MAPK activity involved in osmosensory signaling pathway|termination of MAPK activity during osmolarity sensing|osmolarity sensing, MAPKKK cascade|activation of MAPKK activity during osmolarity sensing|osmolarity sensing, activation of MAP kinase kinase kinase activity|activation of Pbs2 kinase|Hog1 MAPK pathway|MAPKKK cascade involved in osmosensory signaling pathway|activation of MAPKK activity involved in osmosensory signaling pathway|High Osmolarity Glycerol (HOG) MAPK pathway|osmolarity sensing, activation of MAPKKK activity|osmolarity sensing, activation of MAPK activity http://purl.obolibrary.org/obo/GO_0000161 GO:0048103 biolink:BiologicalProcess somatic stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. go-plus.json somatic stem cell renewal http://purl.obolibrary.org/obo/GO_0048103 CHEBI:63299 biolink:ChemicalSubstance carbohydrate derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63299 GO:0048102 biolink:BiologicalProcess autophagic cell death A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. go-plus.json autophagic death|type II programmed cell death|programmed cell death by macroautophagy|autosis|programmed cell death by autophagy http://purl.obolibrary.org/obo/GO_0048102 GO:0000160 biolink:BiologicalProcess phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. go-plus.json phosphorelay signal transduction system|histidyl-aspartyl phosphorelay http://purl.obolibrary.org/obo/GO_0000160 goslim_metagenomics CL:0011020 biolink:Cell neural progenitor cell An undifferentiated cell that originates from a neural stem cell and has the capacity to generate multiple types of lineage-restricted progenitors but not to self-renew. go-plus.json http://purl.obolibrary.org/obo/CL_0011020 CHEBI:133452 biolink:ChemicalSubstance (5R)-5-[(alpha-D-glucosyl-(1->2)-beta-D-galactosyl)oxy]-L-lysine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133452 chebi_ph7_3 CHEBI:133455 biolink:ChemicalSubstance (2E)-dec-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_133455 chebi_ph7_3 CHEBI:133457 biolink:ChemicalSubstance (3E)-3-nonen-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_133457 chebi_ph7_3 CHEBI:133450 biolink:ChemicalSubstance (2E)-enoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133450 chebi_ph7_3 GO:0000178 biolink:CellularComponent exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. go-plus.json exosome (ribonucleasease complex)|exosome multienzyme ribonuclease complex http://purl.obolibrary.org/obo/GO_0000178 goslim_pir GO:0048112 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048112 GO:0000177 biolink:CellularComponent cytoplasmic exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. go-plus.json prokaryotic exosome multienzyme ribonuclease complex|cytoplasmic exosome (ribonuclease complex)|cytoplasmic exosome multienzyme ribonuclease complex http://purl.obolibrary.org/obo/GO_0000177 GO:0048111 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048111 GO:0000176 biolink:CellularComponent nuclear exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. go-plus.json eukaryotic exosome multienzyme ribonuclease complex|nuclear exosome (ribonuclease complex)|nuclear exosome multienzyme ribonuclease complex http://purl.obolibrary.org/obo/GO_0000176 GO:0048110 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048110 GO:0000175 biolink:MolecularActivity 3'-5'-exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. Reactome:R-HSA-9694632|Reactome:R-HSA-6791222|EC:3.1.13.-|Reactome:R-HSA-430028|Reactome:R-HSA-6791227|Reactome:R-HSA-9682603 go-plus.json 3'-5' exoribonuclease activity http://purl.obolibrary.org/obo/GO_0000175 GO:1903519 biolink:BiologicalProcess regulation of mammary gland involution Any process that modulates the frequency, rate or extent of mammary gland involution. go-plus.json http://purl.obolibrary.org/obo/GO_1903519 GO:1903518 biolink:BiologicalProcess positive regulation of single strand break repair Any process that activates or increases the frequency, rate or extent of single strand break repair. go-plus.json up regulation of single strand break repair|upregulation of single strand break repair|up-regulation of single strand break repair|activation of single strand break repair http://purl.obolibrary.org/obo/GO_1903518 GO:1903517 biolink:BiologicalProcess negative regulation of single strand break repair Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair. go-plus.json down-regulation of single strand break repair|downregulation of single strand break repair|down regulation of single strand break repair|inhibition of single strand break repair http://purl.obolibrary.org/obo/GO_1903517 CHEBI:87251 biolink:ChemicalSubstance monoacylglycerol 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_87251 chebi_ph7_3 GO:0000179 biolink:MolecularActivity rRNA (adenine-N6,N6-)-dimethyltransferase activity Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor. Reactome:R-HSA-6790994|Reactome:R-HSA-6793066 go-plus.json dimethyladenosine transferase activity|18S rRNA dimethylase activity|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity http://purl.obolibrary.org/obo/GO_0000179 GO:1903516 biolink:BiologicalProcess regulation of single strand break repair Any process that modulates the frequency, rate or extent of single strand break repair. go-plus.json http://purl.obolibrary.org/obo/GO_1903516 CL:0011016 biolink:Cell flagellated sperm cell A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion. go-plus.json http://purl.obolibrary.org/obo/CL_0011016 GO:0000170 biolink:MolecularActivity sphingosine hydroxylase activity Catalysis of the hydroxylation of sphingolipid long chain bases. Reactome:R-HSA-428260 go-plus.json http://purl.obolibrary.org/obo/GO_0000170 GO:1903515 biolink:BiologicalProcess calcium ion transport from cytosol to endoplasmic reticulum The directed movement of calcium ion from cytosol to endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_1903515 GO:0048119 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048119 GO:1903514 biolink:BiologicalProcess release of sequestered calcium ion into cytosol by endoplasmic reticulum The directed movement of calcium ion from endoplasmic reticulum to cytosol. go-plus.json calcium ion transport from endoplasmic reticulum to cytosol http://purl.obolibrary.org/obo/GO_1903514 CL:0011015 biolink:Cell amoeboid sperm cell A motile sperm cell that contain no F-actin, and their motility is powered by a dynamic filament system. go-plus.json http://purl.obolibrary.org/obo/CL_0011015 GO:0048118 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048118 CHEBI:87255 biolink:ChemicalSubstance monoacylglycerol 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_87255 chebi_ph7_3 CL:0011014 biolink:Cell non-motile sperm cell A sperm cell that is not cabaple of motion (motility). go-plus.json http://purl.obolibrary.org/obo/CL_0011014 GO:1903513 biolink:BiologicalProcess endoplasmic reticulum to cytosol transport The directed movement of substances from endoplasmic reticulum to cytosol. go-plus.json ER to cytosol transport http://purl.obolibrary.org/obo/GO_1903513 CL:0011013 biolink:Cell motile sperm cell A sperm cell that is cabaple of motion (motility). go-plus.json http://purl.obolibrary.org/obo/CL_0011013 GO:0048117 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048117 GO:1903512 biolink:BiologicalProcess phytanic acid metabolic process The chemical reactions and pathways involving phytanic acid. go-plus.json phytanic acid metabolism http://purl.obolibrary.org/obo/GO_1903512 GO:1903511 biolink:BiologicalProcess orotic acid metabolic process The chemical reactions and pathways involving orotic acid. go-plus.json orotic acid metabolism http://purl.obolibrary.org/obo/GO_1903511 CHEBI:87257 biolink:ChemicalSubstance monoacylglycerol 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_87257 chebi_ph7_3 GO:0000174 biolink:BiologicalProcess obsolete inactivation of MAPK (mating sensu Saccharomyces) OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. go-plus.json inactivation of MAPK (mating sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0000174 CL:0011012 biolink:Cell neural crest cell A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. go-plus.json http://purl.obolibrary.org/obo/CL_0011012 GO:0048116 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048116 GO:1903510 biolink:BiologicalProcess mucopolysaccharide metabolic process The chemical reactions and pathways involving mucopolysaccharide. go-plus.json mucopolysaccharide metabolism http://purl.obolibrary.org/obo/GO_1903510 CHEBI:87256 biolink:ChemicalSubstance monoacylglycerol 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_87256 chebi_ph7_3 GO:0000173 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000173 GO:0048115 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048115 GO:0000172 biolink:CellularComponent ribonuclease MRP complex A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication. go-plus.json RNase MRP complex|ribonuclease mitochondrial RNA processing complex http://purl.obolibrary.org/obo/GO_0000172 CHEBI:87259 biolink:ChemicalSubstance (E)-2-methylpentadec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87259 GO:0048114 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048114 GO:0000171 biolink:MolecularActivity ribonuclease MRP activity Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA. Wikipedia:RNase_MRP go-plus.json RNase MRP http://purl.obolibrary.org/obo/GO_0000171 GO:0048113 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048113 CL:0011019 biolink:Cell mesothelial cell of epicardium A mesothelial cell that is part of the epicardium. go-plus.json http://purl.obolibrary.org/obo/CL_0011019 GO:0000145 biolink:CellularComponent exocyst A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. Wikipedia:Exocyst go-plus.json exocyst complex|Sec6/8 complex http://purl.obolibrary.org/obo/GO_0000145 GO:0048123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048123 GO:0048122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048122 GO:0000144 biolink:CellularComponent cellular bud neck septin ring A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0000144 GO:0000143 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000143 GO:0048121 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048121 GO:0000142 biolink:CellularComponent cellular bud neck contractile ring A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae. go-plus.json neck ring http://purl.obolibrary.org/obo/GO_0000142 GO:0048120 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048120 GO:0000149 biolink:MolecularActivity SNARE binding Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. Reactome:R-HSA-210430|Reactome:R-HSA-376364|Reactome:R-HSA-380905|Reactome:R-HSA-9023173|Reactome:R-HSA-374899|Reactome:R-HSA-380901|Reactome:R-HSA-380869|Reactome:R-HSA-888589|Reactome:R-HSA-210426|Reactome:R-HSA-372505|Reactome:R-HSA-917744|Reactome:R-HSA-374922|Reactome:R-HSA-265166|Reactome:R-HSA-376357|Reactome:R-HSA-376369|Reactome:R-HSA-372529|Reactome:R-HSA-380574 go-plus.json SNAP receptor binding http://purl.obolibrary.org/obo/GO_0000149 goslim_chembl GO:1903529 biolink:BiologicalProcess negative regulation of dCDP biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process. go-plus.json down-regulation of dCDP anabolism|negative regulation of dCDP anabolism|down-regulation of dCDP synthesis|negative regulation of dCDP synthesis|inhibition of dCDP biosynthetic process|inhibition of dCDP biosynthesis|down-regulation of dCDP formation|negative regulation of dCDP formation|downregulation of dCDP anabolism|down regulation of dCDP anabolism|downregulation of dCDP synthesis|inhibition of dCDP anabolism|downregulation of dCDP formation|down regulation of dCDP biosynthesis|down regulation of dCDP synthesis|down regulation of dCDP biosynthetic process|inhibition of dCDP synthesis|down regulation of dCDP formation|downregulation of dCDP biosynthetic process|downregulation of dCDP biosynthesis|inhibition of dCDP formation|down-regulation of dCDP biosynthetic process|down-regulation of dCDP biosynthesis|negative regulation of dCDP biosynthesis http://purl.obolibrary.org/obo/GO_1903529 GO:0000148 biolink:CellularComponent 1,3-beta-D-glucan synthase complex A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain. go-plus.json (1->3)-beta-glucan synthase complex|1,3-beta-glucan synthase complex http://purl.obolibrary.org/obo/GO_0000148 GO:0000147 biolink:BiologicalProcess actin cortical patch assembly Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0000147 GO:1903528 biolink:BiologicalProcess regulation of dCDP biosynthetic process Any process that modulates the frequency, rate or extent of dCDP biosynthetic process. go-plus.json regulation of dCDP anabolism|regulation of dCDP synthesis|regulation of dCDP formation|regulation of dCDP biosynthesis http://purl.obolibrary.org/obo/GO_1903528 GO:0000146 biolink:MolecularActivity microfilament motor activity A motor activity that generates movement along a microfilament, driven by ATP hydrolysis. EC:5.6.1.8|Reactome:R-HSA-9023171|Reactome:R-HSA-2316352|Reactome:R-HSA-432237 go-plus.json actin-activated ATPase activity|actin filament motor activity|muscle motor activity|actin-filament motor activity|myosin ATPase activity|actin-dependent ATPase activity http://purl.obolibrary.org/obo/GO_0000146 GO:1903527 biolink:BiologicalProcess positive regulation of membrane tubulation Any process that activates or increases the frequency, rate or extent of membrane tubulation. go-plus.json upregulation of membrane tubulation|upregulation of plasma membrane tubulation|up regulation of membrane tubulation|activation of plasma membrane tubulation|up-regulation of plasma membrane tubulation|activation of membrane tubulation|positive regulation of plasma membrane tubulation|up-regulation of membrane tubulation|up regulation of plasma membrane tubulation http://purl.obolibrary.org/obo/GO_1903527 GO:1903526 biolink:BiologicalProcess negative regulation of membrane tubulation Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation. go-plus.json down regulation of plasma membrane tubulation|inhibition of plasma membrane tubulation|down regulation of membrane tubulation|downregulation of membrane tubulation|down-regulation of membrane tubulation|down-regulation of plasma membrane tubulation|negative regulation of plasma membrane tubulation|inhibition of membrane tubulation|downregulation of plasma membrane tubulation http://purl.obolibrary.org/obo/GO_1903526 CL:0011005 biolink:Cell GABAergic interneuron An interneuron that uses GABA as a vesicular neurotransmitter. These interneurons are inhibitory go-plus.json GABAergic inhibitory interneuron http://purl.obolibrary.org/obo/CL_0011005 GO:1903525 biolink:BiologicalProcess regulation of membrane tubulation Any process that modulates the frequency, rate or extent of membrane tubulation. go-plus.json regulation of plasma membrane tubulation|regulation of vesicle scission http://purl.obolibrary.org/obo/GO_1903525 CL:0011004 biolink:Cell lens fiber cell A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. go-plus.json lens fibre cell http://purl.obolibrary.org/obo/CL_0011004 GO:1903524 biolink:BiologicalProcess positive regulation of blood circulation Any process that activates or increases the frequency, rate or extent of blood circulation. go-plus.json up-regulation of blood circulation|activation of hemolymph circulation|up-regulation of hemolymph circulation|upregulation of blood circulation|upregulation of hemolymph circulation|up regulation of blood circulation|activation of blood circulation|up regulation of hemolymph circulation|positive regulation of hemolymph circulation http://purl.obolibrary.org/obo/GO_1903524 GO:0048129 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048129 GO:1903523 biolink:BiologicalProcess negative regulation of blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. go-plus.json down-regulation of hemolymph circulation|negative regulation of hemolymph circulation|inhibition of blood circulation|inhibition of hemolymph circulation|down regulation of blood circulation|downregulation of blood circulation|down regulation of hemolymph circulation|downregulation of hemolymph circulation|down-regulation of blood circulation http://purl.obolibrary.org/obo/GO_1903523 CL:0011002 biolink:Cell lateral motor column neuron A motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. go-plus.json http://purl.obolibrary.org/obo/CL_0011002 GO:0048128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048128 CHEBI:87287 biolink:ChemicalSubstance 4beta-methylzymosterol-4-carbaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_87287 chebi_ph7_3 CL:0011001 biolink:Cell spinal cord motor neuron A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. go-plus.json http://purl.obolibrary.org/obo/CL_0011001 GO:0000141 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000141 GO:1903522 biolink:BiologicalProcess regulation of blood circulation Any process that modulates the frequency, rate or extent of blood circulation. go-plus.json regulation of hemolymph circulation http://purl.obolibrary.org/obo/GO_1903522 GO:0048127 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048127 GO:1903521 biolink:BiologicalProcess positive regulation of mammary gland involution Any process that activates or increases the frequency, rate or extent of mammary gland involution. go-plus.json activation of mammary gland involution|up-regulation of mammary gland involution|up regulation of mammary gland involution|upregulation of mammary gland involution http://purl.obolibrary.org/obo/GO_1903521 GO:0048126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048126 GO:0000140 biolink:MolecularActivity acylglycerone-phosphate reductase activity Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+). RHEA:17341|Reactome:R-HSA-75883|MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN|EC:1.1.1.101 go-plus.json 1-acyldihydroxyacetone-phosphate reductase activity|acyldihydroxyacetone phosphate reductase activity|palmitoyldihydroxyacetone-phosphate reductase activity|palmitoyl dihydroxyacetone phosphate reductase activity|palmitoyl-dihydroxyacetone-phosphate reductase activity|1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0000140 CL:0011000 biolink:Cell dorsal horn interneuron A CNS interneuron located in the dorsal horn of the spinal cord. go-plus.json dorsal spinal cord interneuron http://purl.obolibrary.org/obo/CL_0011000 CHEBI:87289 biolink:ChemicalSubstance 4alpha-hydroxymethyl-4beta-methylzymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87289 chebi_ph7_3 GO:1903520 biolink:BiologicalProcess negative regulation of mammary gland involution Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution. go-plus.json down-regulation of mammary gland involution|downregulation of mammary gland involution|down regulation of mammary gland involution|inhibition of mammary gland involution http://purl.obolibrary.org/obo/GO_1903520 GO:0048125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048125 GO:0048124 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048124 PR:000001489 biolink:Protein neuromedin-U receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human NMUR1 or NMUR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json neuromedin U receptor|fam:NMU_R http://purl.obolibrary.org/obo/PR_000001489 PR:000001488 biolink:Protein muscarinic acetylcholine receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human CHRM1 to CHRM5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000001488 CL:0011006 biolink:Cell Lugaro cell An inhibitory GABAergic interneuron found in the cerebellar cortex. go-plus.json http://purl.obolibrary.org/obo/CL_0011006 GO:0048134 biolink:BiologicalProcess germ-line cyst formation Formation of a group of interconnected cells derived from a single gonial founder cell. go-plus.json germline cyst formation http://purl.obolibrary.org/obo/GO_0048134 GO:0000156 biolink:MolecularActivity phosphorelay response regulator activity Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response. go-plus.json two-component response regulator activity http://purl.obolibrary.org/obo/GO_0000156 GO:0048133 biolink:BiologicalProcess male germ-line stem cell asymmetric division The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes. go-plus.json male germ-line stem cell renewal http://purl.obolibrary.org/obo/GO_0048133 GO:0000155 biolink:MolecularActivity phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. EC:2.7.3.- go-plus.json two-component sensor activity|two-component sensor molecule|two-component system sensor activity http://purl.obolibrary.org/obo/GO_0000155 GO:0000154 biolink:BiologicalProcess rRNA modification The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically. go-plus.json rRNA editing http://purl.obolibrary.org/obo/GO_0000154 GO:0048132 biolink:BiologicalProcess female germ-line stem cell asymmetric division The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes. go-plus.json female germ-line stem cell renewal http://purl.obolibrary.org/obo/GO_0048132 GO:0000153 biolink:CellularComponent cytoplasmic ubiquitin ligase complex A ubiquitin ligase complex found in the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0000153 GO:0048131 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048131 GO:0048130 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048130 GO:0000159 biolink:CellularComponent protein phosphatase type 2A complex A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. go-plus.json PP2A complex|PP2A-pi|PP2a-protector|protein phosphatase 2 complex http://purl.obolibrary.org/obo/GO_0000159 GO:0000158 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000158 GO:1903539 biolink:BiologicalProcess protein localization to postsynaptic membrane A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane. go-plus.json protein localization in postsynaptic membrane|protein localisation in postsynaptic membrane|protein localisation to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1903539 GO:1903538 biolink:BiologicalProcess regulation of meiotic cell cycle process involved in oocyte maturation Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. go-plus.json regulation of meiosis involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1903538 GO:0000157 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000157 GO:1903537 biolink:BiologicalProcess meiotic cell cycle process involved in oocyte maturation Any meiotic cell cycle process that is involved in oocyte maturation. go-plus.json meiosis involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1903537 GO:1903536 biolink:BiologicalProcess positive regulation of lactose biosynthetic process Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process. go-plus.json up-regulation of lactose anabolism|positive regulation of lactose biosynthesis|up-regulation of lactose synthesis|up regulation of lactose biosynthetic process|up regulation of lactose biosynthesis|up-regulation of lactose formation|upregulation of lactose anabolism|upregulation of lactose synthesis|upregulation of lactose biosynthetic process|upregulation of lactose biosynthesis|upregulation of lactose formation|up regulation of lactose anabolism|activation of lactose anabolism|positive regulation of lactose anabolism|up regulation of lactose synthesis|up-regulation of lactose biosynthetic process|up-regulation of lactose biosynthesis|activation of lactose synthesis|positive regulation of lactose synthesis|activation of lactose biosynthesis|activation of lactose biosynthetic process|up regulation of lactose formation|activation of lactose formation|positive regulation of lactose formation http://purl.obolibrary.org/obo/GO_1903536 CHEBI:133449 biolink:ChemicalSubstance hydroxy-fatty acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133449 chebi_ph7_3 GO:1903535 biolink:BiologicalProcess negative regulation of lactose biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process. go-plus.json negative regulation of lactose formation|down-regulation of lactose formation|inhibition of lactose synthesis|inhibition of lactose formation|downregulation of lactose biosynthetic process|downregulation of lactose biosynthesis|down regulation of lactose biosynthesis|down regulation of lactose biosynthetic process|down regulation of lactose anabolism|inhibition of lactose biosynthesis|inhibition of lactose biosynthetic process|downregulation of lactose anabolism|down regulation of lactose synthesis|down regulation of lactose formation|downregulation of lactose synthesis|downregulation of lactose formation|negative regulation of lactose anabolism|down-regulation of lactose anabolism|negative regulation of lactose synthesis|down-regulation of lactose synthesis|inhibition of lactose anabolism|negative regulation of lactose biosynthesis|down-regulation of lactose biosynthesis|down-regulation of lactose biosynthetic process http://purl.obolibrary.org/obo/GO_1903535 CHEBI:87277 biolink:ChemicalSubstance 3beta-hydroxy-4beta-methyl-5alpha-cholest-8-ene-4alpha-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87277 GO:1903534 biolink:BiologicalProcess regulation of lactose biosynthetic process Any process that modulates the frequency, rate or extent of lactose biosynthetic process. go-plus.json regulation of lactose biosynthesis|regulation of lactose anabolism|regulation of lactose synthesis|regulation of lactose formation http://purl.obolibrary.org/obo/GO_1903534 GO:0048139 biolink:BiologicalProcess female germ-line cyst encapsulation Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad. go-plus.json http://purl.obolibrary.org/obo/GO_0048139 GO:0000152 biolink:CellularComponent nuclear ubiquitin ligase complex A ubiquitin ligase complex found in the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0000152 GO:1903533 biolink:BiologicalProcess regulation of protein targeting Any process that modulates the frequency, rate or extent of protein targeting. go-plus.json regulation of protein sorting along secretory pathway|regulation of nascent polypeptide association http://purl.obolibrary.org/obo/GO_1903533 GO:0048138 biolink:BiologicalProcess germ-line cyst encapsulation Formation of a single follicular epithelium around the germ-line derived cells of a cyst. go-plus.json http://purl.obolibrary.org/obo/GO_0048138 GO:1903532 biolink:BiologicalProcess positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of secretion by cell. go-plus.json up regulation of secretion by cell|activation of secretion by cell|up-regulation of cellular secretion|activation of cellular secretion|up-regulation of secretion by cell|positive regulation of cellular secretion|up regulation of cellular secretion|upregulation of secretion by cell|upregulation of cellular secretion http://purl.obolibrary.org/obo/GO_1903532 GO:0048137 biolink:BiologicalProcess spermatocyte division The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids. go-plus.json spermatocyte cell division http://purl.obolibrary.org/obo/GO_0048137 GO:0000151 biolink:CellularComponent ubiquitin ligase complex A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex. go-plus.json http://purl.obolibrary.org/obo/GO_0000151 goslim_pir GO:0000150 biolink:MolecularActivity DNA strand exchange activity Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. Reactome:R-HSA-912458 go-plus.json recombinase activity|strand transferase|RecA-family recombinase activity|strand exchange activity http://purl.obolibrary.org/obo/GO_0000150 goslim_metagenomics GO:1903531 biolink:BiologicalProcess negative regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. go-plus.json down-regulation of secretion by cell|down-regulation of cellular secretion|negative regulation of cellular secretion|inhibition of secretion by cell|downregulation of cellular secretion|down regulation of cellular secretion|down regulation of secretion by cell|inhibition of cellular secretion|downregulation of secretion by cell http://purl.obolibrary.org/obo/GO_1903531 GO:0048136 biolink:BiologicalProcess male germ-line cyst formation Formation of a group of interconnected cells derived from a single male gonial founder cell. go-plus.json male germline cyst formation http://purl.obolibrary.org/obo/GO_0048136 GO:0048135 biolink:BiologicalProcess female germ-line cyst formation Formation of a group of interconnected cells derived from a single female gonial founder cell. go-plus.json female germline cyst formation http://purl.obolibrary.org/obo/GO_0048135 GO:1903530 biolink:BiologicalProcess regulation of secretion by cell Any process that modulates the frequency, rate or extent of secretion by cell. go-plus.json regulation of cellular secretion http://purl.obolibrary.org/obo/GO_1903530 GO:1903540 biolink:BiologicalProcess establishment of protein localization to postsynaptic membrane The directed movement of a protein to a specific location in a postsynaptic membrane. go-plus.json establishment of protein localisation to postsynaptic membrane|establishment of protein localization in postsynaptic membrane|establishment of protein localisation in postsynaptic membrane http://purl.obolibrary.org/obo/GO_1903540 CHEBI:133442 biolink:ChemicalSubstance (5R)-5-hydroxy-L-lysine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133442 chebi_ph7_3 CHEBI:133444 biolink:ChemicalSubstance 1-O-acylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133444 chebi_ph7_3 CHEBI:133443 biolink:ChemicalSubstance (5R)-5-(beta-D-galactosyloxy)-L-lysine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133443 chebi_ph7_3 PR:000001498 biolink:Protein pyroglutamylated RF-amide peptide receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human QRFPR gene or a 1:1 ortholog thereof. go-plus.json GPR103|SP9155|AQ27|orexigenic neuropeptide QRFP receptor|G-protein coupled receptor 103|QRFPR http://purl.obolibrary.org/obo/PR_000001498 CHEBI:133446 biolink:ChemicalSubstance monounsaturated fatty acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133446 chebi_ph7_3 PR:000001497 biolink:Protein opioid receptor protein A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPRD1, OPRK1, OPRM1, or OPRL1 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000001497 CHEBI:133445 biolink:ChemicalSubstance saturated fatty acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133445 chebi_ph7_3 CHEBI:133448 biolink:ChemicalSubstance oxo-fatty acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133448 chebi_ph7_3 PR:000001499 biolink:Protein orexin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human HCRTR1 or HCRTR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json hypocretin receptor http://purl.obolibrary.org/obo/PR_000001499 CHEBI:133447 biolink:ChemicalSubstance methyl-branched fatty acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133447 chebi_ph7_3 GO:0000123 biolink:CellularComponent histone acetyltransferase complex A protein complex that possesses histone acetyltransferase activity. go-plus.json histone acetylase complex http://purl.obolibrary.org/obo/GO_0000123 GO:0048145 biolink:BiologicalProcess regulation of fibroblast proliferation Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048145 GO:0000122 biolink:BiologicalProcess negative regulation of transcription by RNA polymerase II Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. go-plus.json down-regulation of global transcription from RNA polymerase II promoter|negative regulation of transcription from Pol II promoter|negative regulation of global transcription from Pol II promoter|inhibition of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, global|downregulation of global transcription from RNA polymerase II promoter|down regulation of global transcription from RNA polymerase II promoter|down regulation of transcription from RNA polymerase II promoter|downregulation of transcription from RNA polymerase II promoter|inhibition of global transcription from RNA polymerase II promoter|negative regulation of gene-specific transcription from RNA polymerase II promoter|down-regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0000122 GO:0048144 biolink:BiologicalProcess fibroblast proliferation The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. go-plus.json http://purl.obolibrary.org/obo/GO_0048144 GO:0000121 biolink:MolecularActivity glycerol-1-phosphatase activity Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate. EC:3.1.3.21|RHEA:11476|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN go-plus.json glycerol-3-phosphate phosphatase activity|glycerol 3-phosphate phosphohydrolase activity|alpha-glycerophosphatase activity|glycerol 3-phosphatase activity|glycerol-1-phosphate phosphohydrolase activity|alpha-glycerol phosphatase activity http://purl.obolibrary.org/obo/GO_0000121 GO:0048143 biolink:BiologicalProcess astrocyte activation A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0048143 GO:0048142 biolink:BiologicalProcess germarium-derived cystoblast division The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster. go-plus.json germarium-derived cystoblast cell division http://purl.obolibrary.org/obo/GO_0048142 GO:0000120 biolink:CellularComponent RNA polymerase I transcription regulator complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I. go-plus.json RNA polymerase I transcription factor complex http://purl.obolibrary.org/obo/GO_0000120 GO:0048141 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048141 GO:0000127 biolink:CellularComponent transcription factor TFIIIC complex A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions. go-plus.json http://purl.obolibrary.org/obo/GO_0000127 GO:0048140 biolink:BiologicalProcess male germ-line cyst encapsulation Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad. go-plus.json http://purl.obolibrary.org/obo/GO_0048140 GO:0000126 biolink:CellularComponent transcription factor TFIIIB complex A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF. go-plus.json http://purl.obolibrary.org/obo/GO_0000126 CHEBI:38291 biolink:ChemicalSubstance dihydrostreptomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38291 GO:0000125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000125 GO:1903549 biolink:BiologicalProcess positive regulation of growth hormone activity Any process that activates or increases the frequency, rate or extent of growth hormone activity. go-plus.json up-regulation of placental growth hormone activity|upregulation of growth hormone activity|up regulation of GH activity|up regulation of pituitary growth hormone activity|activation of GH activity|positive regulation of GH activity|upregulation of placental growth hormone activity|positive regulation of pituitary growth hormone activity|activation of pituitary growth hormone activity|up regulation of growth hormone activity|activation of growth hormone activity|up regulation of placental growth hormone activity|up-regulation of GH activity|up-regulation of pituitary growth hormone activity|positive regulation of placental growth hormone activity|activation of placental growth hormone activity|upregulation of GH activity|up-regulation of growth hormone activity|upregulation of pituitary growth hormone activity http://purl.obolibrary.org/obo/GO_1903549 GO:0000124 biolink:CellularComponent SAGA complex A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695). go-plus.json STAGA complex|SPT3-TAF9-GCN5 acetylase complex|Spt-Ada-Gcn5-acetyltransferase complex|STAGA coactivator complex|PCAF complex|SPT3-TAF9-PCAF acetylase complex|PCAF histone acetylase-associated complex http://purl.obolibrary.org/obo/GO_0000124 CHEBI:38290 biolink:ChemicalSubstance L-ascorbate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38290 chebi_ph7_3 GO:1903548 biolink:BiologicalProcess negative regulation of growth hormone activity Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity. go-plus.json down regulation of GH activity|down regulation of pituitary growth hormone activity|downregulation of GH activity|inhibition of placental growth hormone activity|downregulation of pituitary growth hormone activity|down regulation of growth hormone activity|down regulation of placental growth hormone activity|down-regulation of GH activity|negative regulation of GH activity|downregulation of growth hormone activity|down-regulation of pituitary growth hormone activity|negative regulation of pituitary growth hormone activity|downregulation of placental growth hormone activity|inhibition of GH activity|down-regulation of growth hormone activity|negative regulation of placental growth hormone activity|down-regulation of placental growth hormone activity|inhibition of pituitary growth hormone activity|inhibition of growth hormone activity http://purl.obolibrary.org/obo/GO_1903548 CHEBI:133417 biolink:ChemicalSubstance O-[S-(18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133417 chebi_ph7_3 GO:1903547 biolink:BiologicalProcess regulation of growth hormone activity Any process that modulates the frequency, rate or extent of growth hormone activity. go-plus.json regulation of GH activity|regulation of pituitary growth hormone activity|regulation of placental growth hormone activity http://purl.obolibrary.org/obo/GO_1903547 GO:1903546 biolink:BiologicalProcess protein localization to photoreceptor outer segment A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment. go-plus.json protein localisation to photoreceptor outer segment|protein localization in photoreceptor outer segment|protein localisation in photoreceptor outer segment http://purl.obolibrary.org/obo/GO_1903546 CHEBI:133419 biolink:ChemicalSubstance 2-isobutyrylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_133419 chebi_ph7_3 GO:1903545 biolink:BiologicalProcess cellular response to butyrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903545 CL:0001658 biolink:Cell visual pigment cell (sensu Nematoda and Protostomia) go-plus.json http://purl.obolibrary.org/obo/CL_0001658 GO:1903544 biolink:BiologicalProcess response to butyrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903544 GO:0048149 biolink:BiologicalProcess behavioral response to ethanol Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus. go-plus.json behavioural response to ethanol http://purl.obolibrary.org/obo/GO_0048149 GO:1903543 biolink:BiologicalProcess positive regulation of exosomal secretion Any process that activates or increases the frequency, rate or extent of exosomal secretion. go-plus.json positive regulation of exosomal protein secretion|upregulation of extracellular vesicular exosome secretion|up regulation of exosomal protein secretion|activation of exosomal secretory pathway|up-regulation of exosomal secretory pathway|up-regulation of secretion of exosome|activation of secretion of exosome|up regulation of extracellular vesicular exosome secretion|up regulation of exosomal secretion|upregulation of exosomal protein secretion|activation of extracellular vesicular exosome secretion|positive regulation of extracellular vesicular exosome secretion|positive regulation of exosomal secretory pathway|positive regulation of secretion of exosome|up regulation of exosomal secretory pathway|up regulation of secretion of exosome|up-regulation of exosomal protein secretion|upregulation of exosomal secretion|up-regulation of extracellular vesicular exosome secretion|activation of exosomal protein secretion|upregulation of exosomal secretory pathway|upregulation of secretion of exosome|up-regulation of exosomal secretion|activation of exosomal secretion http://purl.obolibrary.org/obo/GO_1903543 GO:0048148 biolink:BiologicalProcess behavioral response to cocaine Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus. go-plus.json behavioural response to cocaine http://purl.obolibrary.org/obo/GO_0048148 GO:1903542 biolink:BiologicalProcess negative regulation of exosomal secretion Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion. go-plus.json down regulation of extracellular vesicular exosome secretion|down-regulation of exosomal secretion|downregulation of exosomal protein secretion|downregulation of extracellular vesicular exosome secretion|down regulation of exosomal protein secretion|down-regulation of exosomal secretory pathway|negative regulation of exosomal secretory pathway|negative regulation of secretion of exosome|downregulation of exosomal secretion|down-regulation of secretion of exosome|negative regulation of extracellular vesicular exosome secretion|inhibition of exosomal protein secretion|down-regulation of extracellular vesicular exosome secretion|down regulation of exosomal secretion|inhibition of exosomal secretion|downregulation of exosomal secretory pathway|downregulation of secretion of exosome|inhibition of extracellular vesicular exosome secretion|down regulation of exosomal secretory pathway|down regulation of secretion of exosome|inhibition of exosomal secretory pathway|inhibition of secretion of exosome|negative regulation of exosomal protein secretion|down-regulation of exosomal protein secretion http://purl.obolibrary.org/obo/GO_1903542 GO:0048147 biolink:BiologicalProcess negative regulation of fibroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. go-plus.json down-regulation of fibroblast proliferation|downregulation of fibroblast proliferation|down regulation of fibroblast proliferation|inhibition of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0048147 GO:0048146 biolink:BiologicalProcess positive regulation of fibroblast proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. go-plus.json activation of fibroblast proliferation|up regulation of fibroblast proliferation|upregulation of fibroblast proliferation|stimulation of fibroblast proliferation|up-regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0048146 GO:1903541 biolink:BiologicalProcess regulation of exosomal secretion Any process that modulates the frequency, rate or extent of exosomal secretion. go-plus.json regulation of extracellular vesicular exosome secretion|regulation of exosomal protein secretion|regulation of exosomal secretory pathway|regulation of secretion of exosome http://purl.obolibrary.org/obo/GO_1903541 GO:1903551 biolink:BiologicalProcess regulation of extracellular exosome assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. go-plus.json regulation of extracellular vesicular exosome assembly http://purl.obolibrary.org/obo/GO_1903551 CHEBI:133411 biolink:ChemicalSubstance 13,14-dihydro-15-keto-PGF1alpha(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133411 chebi_ph7_3 CHEBI:133415 biolink:ChemicalSubstance O-(S-malonamoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133415 chebi_ph7_3 CHEBI:133414 biolink:ChemicalSubstance N-acetyl-L-methionyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133414 chebi_ph7_3 GO:0000129 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000129 GO:0000128 biolink:BiologicalProcess flocculation The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. Wikipedia:Flocculation go-plus.json coflocculation via lectin-mannose interaction|co-flocculation|cell-cell adhesion involved in flocculation|cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction|coflocculation|flocculation via extracellular polymer|coflocculation via protein-carbohydrate interaction|flocculation via cell wall protein-carbohydrate interaction http://purl.obolibrary.org/obo/GO_0000128 goslim_pir GO:0000134 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000134 GO:0048156 biolink:MolecularActivity tau protein binding Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS. go-plus.json http://purl.obolibrary.org/obo/GO_0048156 GO:0000133 biolink:CellularComponent polarisome Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p. go-plus.json http://purl.obolibrary.org/obo/GO_0000133 goslim_pir GO:0048155 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048155 GO:0000132 biolink:BiologicalProcess establishment of mitotic spindle orientation A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. go-plus.json establishment of spindle orientation during mitosis|mitotic spindle orientation|establishment of spindle orientation involved in mitotic cell cycle|orienting of mitotic spindle http://purl.obolibrary.org/obo/GO_0000132 GO:0048154 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048154 GO:0048153 biolink:BiologicalProcess obsolete S100 alpha biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS. go-plus.json S100 alpha anabolism|S100 alpha biosynthesis|S100 alpha synthesis|S100 alpha formation http://purl.obolibrary.org/obo/GO_0048153 GO:0000131 biolink:CellularComponent incipient cellular bud site The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence. go-plus.json http://purl.obolibrary.org/obo/GO_0000131 GO:0000138 biolink:CellularComponent Golgi trans cisterna The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed. go-plus.json late Golgi http://purl.obolibrary.org/obo/GO_0000138 GO:0048152 biolink:BiologicalProcess obsolete S100 beta biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS. go-plus.json S100 beta anabolism|S100 beta synthesis|S100 beta formation|S100 beta biosynthesis http://purl.obolibrary.org/obo/GO_0048152 CHEBI:87293 biolink:ChemicalSubstance 3beta-hydroxy-5alpha-cholest-8-ene-4alpha-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87293 GO:0000137 biolink:CellularComponent Golgi cis cisterna The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER. go-plus.json http://purl.obolibrary.org/obo/GO_0000137 GO:0048151 biolink:BiologicalProcess obsolete hyperphosphorylation OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both. go-plus.json hyperphosphorylation http://purl.obolibrary.org/obo/GO_0048151 GO:0000136 biolink:CellularComponent mannan polymerase complex A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins. go-plus.json alpha-1,6-mannosyltransferase complex http://purl.obolibrary.org/obo/GO_0000136 GO:0048150 biolink:BiologicalProcess behavioral response to ether Any process that results in a change in the behavior of an organism as a result of an ether stimulus. go-plus.json behavioural response to ether http://purl.obolibrary.org/obo/GO_0048150 GO:0000135 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000135 GO:1903559 biolink:BiologicalProcess 3-cyano-L-alanine catabolic process The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine. go-plus.json 3-cyano-L-alanine catabolism|3-cyano-L-alanine degradation|3-cyano-L-alanine breakdown http://purl.obolibrary.org/obo/GO_1903559 GO:1903558 biolink:BiologicalProcess 3-cyano-L-alanine metabolic process The chemical reactions and pathways involving 3-cyano-L-alanine. go-plus.json 3-cyano-L-alanine metabolism http://purl.obolibrary.org/obo/GO_1903558 CHEBI:133427 biolink:ChemicalSubstance omega-ammonioaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_133427 chebi_ph7_3 GO:1903557 biolink:BiologicalProcess positive regulation of tumor necrosis factor superfamily cytokine production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. go-plus.json activation of TNF superfamily production|up regulation of tumor necrosis factor superfamily cytokine production|upregulation of TNFSF cytokine production|activation of tumor necrosis factor superfamily cytokine production|positive regulation of TNF superfamily production|up regulation of TNF superfamily production|up regulation of TNFSF cytokine production|activation of TNFSF cytokine production|positive regulation of TNFSF cytokine production|up-regulation of tumor necrosis factor superfamily cytokine production|upregulation of TNF superfamily production|upregulation of tumor necrosis factor superfamily cytokine production|up-regulation of TNF superfamily production|up-regulation of TNFSF cytokine production http://purl.obolibrary.org/obo/GO_1903557 GO:1903556 biolink:BiologicalProcess negative regulation of tumor necrosis factor superfamily cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. go-plus.json downregulation of tumor necrosis factor superfamily cytokine production|down-regulation of TNF superfamily production|negative regulation of TNF superfamily production|down regulation of TNFSF cytokine production|down-regulation of tumor necrosis factor superfamily cytokine production|downregulation of TNF superfamily production|downregulation of TNFSF cytokine production|down regulation of TNF superfamily production|inhibition of tumor necrosis factor superfamily cytokine production|negative regulation of TNFSF cytokine production|down-regulation of TNFSF cytokine production|inhibition of TNF superfamily production|inhibition of TNFSF cytokine production|down regulation of tumor necrosis factor superfamily cytokine production http://purl.obolibrary.org/obo/GO_1903556 GO:1903555 biolink:BiologicalProcess regulation of tumor necrosis factor superfamily cytokine production Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. go-plus.json regulation of TNFSF cytokine production|regulation of TNF superfamily production http://purl.obolibrary.org/obo/GO_1903555 GO:0000130 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000130 GO:1903554 biolink:BiologicalProcess G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium. go-plus.json G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in Gram-negative antibacterial peptide activity|GPCR signalling pathway involved in defence response to Gram-negative bacterium|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defence response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacteria|GPCR signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|GPCR signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacterium|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|GPCR signaling pathway involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G-protein-coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in Gram-negative antibacterial peptide activity http://purl.obolibrary.org/obo/GO_1903554 GO:0048159 biolink:BiologicalProcess primary oocyte stage The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells. go-plus.json mammalian oogenesis stage 2 http://purl.obolibrary.org/obo/GO_0048159 GO:1903553 biolink:BiologicalProcess positive regulation of extracellular exosome assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. go-plus.json upregulation of extracellular vesicular exosome assembly|up-regulation of extracellular vesicular exosome assembly|activation of extracellular vesicular exosome assembly|positive regulation of extracellular vesicular exosome assembly|up regulation of extracellular vesicular exosome assembly http://purl.obolibrary.org/obo/GO_1903553 GO:0048158 biolink:BiologicalProcess oogonium stage The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary. go-plus.json mammalian oogenesis stage 1 http://purl.obolibrary.org/obo/GO_0048158 GO:1903552 biolink:BiologicalProcess negative regulation of extracellular exosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. go-plus.json down regulation of extracellular vesicular exosome assembly|inhibition of extracellular vesicular exosome assembly|negative regulation of extracellular vesicular exosome assembly|down-regulation of extracellular vesicular exosome assembly|downregulation of extracellular vesicular exosome assembly http://purl.obolibrary.org/obo/GO_1903552 GO:0048157 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048157 GO:1903562 biolink:BiologicalProcess microtubule bundle formation involved in mitotic spindle midzone assembly Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis. go-plus.json microtubule bundle formation involved in mitotic spindle midzone formation|microtubule bundle formation involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in mitotic spindle midzone assembly|microtubule bundling involved in spindle midzone formation involved in mitosis|microtubule bundling involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in spindle midzone biogenesis involved in mitosis|microtubule bundling involved in mitotic spindle midzone formation|microtubule bundle formation involved in mitotic spindle midzone assembly http://purl.obolibrary.org/obo/GO_1903562 GO:1903561 biolink:CellularComponent extracellular vesicle Any vesicle that is part of the extracellular region. go-plus.json microparticle http://purl.obolibrary.org/obo/GO_1903561 GO:1903560 biolink:BiologicalProcess 3-cyano-L-alanine biosynthetic process The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine. go-plus.json 3-cyano-L-alanine anabolism|3-cyano-L-alanine biosynthesis|3-cyano-L-alanine synthesis|3-cyano-L-alanine formation http://purl.obolibrary.org/obo/GO_1903560 CHEBI:133421 biolink:ChemicalSubstance prostaglandin F1alpha (1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133421 chebi_ph7_3 CHEBI:133424 biolink:ChemicalSubstance 13,14-dihydro-Delta(12)-prostaglandin J2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133424 chebi_ph7_3 CHEBI:38297 biolink:ChemicalSubstance thiabicycloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38297 CHEBI:38295 biolink:ChemicalSubstance azabicycloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38295 GO:0000139 biolink:CellularComponent Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus. go-plus.json http://purl.obolibrary.org/obo/GO_0000139 CHEBI:38299 biolink:ChemicalSubstance vernolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38299 CHEBI:38298 biolink:ChemicalSubstance benzodioxoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_38298 GO:0000101 biolink:BiologicalProcess sulfur amino acid transport The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sulphur amino acid transport http://purl.obolibrary.org/obo/GO_0000101 GO:0048167 biolink:BiologicalProcess regulation of synaptic plasticity A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. go-plus.json http://purl.obolibrary.org/obo/GO_0048167 GO:0000100 biolink:MolecularActivity S-methylmethionine transmembrane transporter activity Enables the transfer of S-methylmethionine from one side of a membrane to the other. go-plus.json S-methylmethionine transporter activity|S-methylmethionine permease activity http://purl.obolibrary.org/obo/GO_0000100 GO:0048166 biolink:BiologicalProcess mature follicle stage The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division. go-plus.json mammalian oogenesis stage 9 http://purl.obolibrary.org/obo/GO_0048166 GO:0048165 biolink:BiologicalProcess fused antrum stage The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. go-plus.json mammalian oogenesis stage 8 http://purl.obolibrary.org/obo/GO_0048165 GO:0048164 biolink:BiologicalProcess distinct antral spaces stage The stage in oogenesis when the antral spaces become distinct and the first polar body forms. go-plus.json mammalian oogenesis stage 7 http://purl.obolibrary.org/obo/GO_0048164 GO:0000105 biolink:BiologicalProcess histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. MetaCyc:HISTSYN-PWY go-plus.json histidine anabolism|histidine synthesis|histidine formation|histidine biosynthesis http://purl.obolibrary.org/obo/GO_0000105 GO:0048163 biolink:BiologicalProcess scattered antral spaces stage The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration. go-plus.json mammalian oogenesis stage 6 http://purl.obolibrary.org/obo/GO_0048163 GO:0000104 biolink:MolecularActivity succinate dehydrogenase activity Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. MetaCyc:SUCC-FUM-OXRED-RXN|RHEA:16357 go-plus.json fumarate dehydrogenase activity|succinate:acceptor oxidoreductase activity|succinic dehydrogenase activity|fumarate reductase activity|fumaric hydrogenase activity|succinate oxidoreductase activity|succinodehydrogenase activity|succinyl dehydrogenase activity|succinate:(acceptor) oxidoreductase activity|succinic acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0000104 GO:0048162 biolink:BiologicalProcess multi-layer follicle stage The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. go-plus.json mammalian oogenesis stage 5 http://purl.obolibrary.org/obo/GO_0048162 GO:0000103 biolink:BiologicalProcess sulfate assimilation The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds. go-plus.json sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|sulphate assimilation http://purl.obolibrary.org/obo/GO_0000103 GO:0048161 biolink:BiologicalProcess double layer follicle stage The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus. go-plus.json mammalian oogenesis stage 4 http://purl.obolibrary.org/obo/GO_0048161 GO:0048160 biolink:BiologicalProcess primary follicle stage The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large. go-plus.json mammalian oogenesis stage 3 http://purl.obolibrary.org/obo/GO_0048160 GO:0000102 biolink:MolecularActivity L-methionine secondary active transmembrane transporter activity Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json L-methionine porter activity http://purl.obolibrary.org/obo/GO_0000102 GO:1903569 biolink:BiologicalProcess positive regulation of protein localization to ciliary membrane Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. go-plus.json positive regulation of protein localization in ciliary membrane|upregulation of protein localization to ciliary membrane|up regulation of protein localization in ciliary membrane|activation of protein localisation to ciliary membrane|up-regulation of protein localisation to ciliary membrane|upregulation of protein localisation in ciliary membrane|up-regulation of protein localization to ciliary membrane|activation of protein localization to ciliary membrane|upregulation of protein localization in ciliary membrane|up-regulation of protein localisation in ciliary membrane|activation of protein localisation in ciliary membrane|positive regulation of protein localisation to ciliary membrane|up regulation of protein localisation to ciliary membrane|up-regulation of protein localization in ciliary membrane|activation of protein localization in ciliary membrane|up regulation of protein localization to ciliary membrane|positive regulation of protein localisation in ciliary membrane|up regulation of protein localisation in ciliary membrane|upregulation of protein localisation to ciliary membrane http://purl.obolibrary.org/obo/GO_1903569 GO:1903568 biolink:BiologicalProcess negative regulation of protein localization to ciliary membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. go-plus.json inhibition of protein localization to ciliary membrane|down regulation of protein localisation in ciliary membrane|inhibition of protein localisation in ciliary membrane|downregulation of protein localization in ciliary membrane|down regulation of protein localization in ciliary membrane|negative regulation of protein localisation to ciliary membrane|inhibition of protein localization in ciliary membrane|down-regulation of protein localisation to ciliary membrane|down-regulation of protein localization to ciliary membrane|downregulation of protein localisation to ciliary membrane|down-regulation of protein localisation in ciliary membrane|negative regulation of protein localisation in ciliary membrane|down regulation of protein localisation to ciliary membrane|inhibition of protein localisation to ciliary membrane|downregulation of protein localization to ciliary membrane|down-regulation of protein localization in ciliary membrane|negative regulation of protein localization in ciliary membrane|downregulation of protein localisation in ciliary membrane|down regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1903568 GO:0014748 biolink:BiologicalProcess negative regulation of tonic skeletal muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014748 GO:1903567 biolink:BiologicalProcess regulation of protein localization to ciliary membrane Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. go-plus.json regulation of protein localisation in ciliary membrane|regulation of protein localization in ciliary membrane|regulation of protein localisation to ciliary membrane http://purl.obolibrary.org/obo/GO_1903567 GO:0014747 biolink:BiologicalProcess positive regulation of tonic skeletal muscle contraction Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014747 GO:1903566 biolink:BiologicalProcess positive regulation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. go-plus.json up regulation of protein localization to cilium|upregulation of protein localization to cilium|up-regulation of protein localization to cilium|activation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903566 GO:1903565 biolink:BiologicalProcess negative regulation of protein localization to cilium Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. go-plus.json down-regulation of protein localization to cilium|downregulation of protein localization to cilium|down regulation of protein localization to cilium|inhibition of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903565 GO:0048169 biolink:BiologicalProcess regulation of long-term neuronal synaptic plasticity A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. go-plus.json http://purl.obolibrary.org/obo/GO_0048169 GO:1903564 biolink:BiologicalProcess regulation of protein localization to cilium Any process that modulates the frequency, rate or extent of protein localization to cilium. go-plus.json http://purl.obolibrary.org/obo/GO_1903564 GO:1903563 biolink:BiologicalProcess microtubule bundle formation involved in horsetail-astral microtubule organization Any microtubule bundle formation that is involved in horsetail-astral microtubule organization. go-plus.json microtubule bundling involved in horsetail-astral microtubule organization|microtubule bundle formation involved in horsetail-astral microtubule array organization|microtubule bundle formation involved in horsetail-astral microtubule organisation|microtubule bundling involved in horsetail-astral microtubule organisation|microtubule bundling involved in horsetail-astral microtubule array organization http://purl.obolibrary.org/obo/GO_1903563 GO:0048168 biolink:BiologicalProcess regulation of neuronal synaptic plasticity A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. go-plus.json http://purl.obolibrary.org/obo/GO_0048168 GO:1903573 biolink:BiologicalProcess negative regulation of response to endoplasmic reticulum stress Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress. go-plus.json down-regulation of response to ER stress|negative regulation of cellular response to endoplasmic reticulum stress|down-regulation of cellular response to endoplasmic reticulum stress|negative regulation of response to ER stress|downregulation of response to endoplasmic reticulum stress|inhibition of response to ER stress|down regulation of response to endoplasmic reticulum stress|inhibition of cellular response to endoplasmic reticulum stress|inhibition of response to endoplasmic reticulum stress|down-regulation of ER stress response|negative regulation of ER stress response|down regulation of response to ER stress|down regulation of cellular response to endoplasmic reticulum stress|downregulation of ER stress response|downregulation of response to ER stress|downregulation of cellular response to endoplasmic reticulum stress|down regulation of ER stress response|down-regulation of response to endoplasmic reticulum stress|inhibition of ER stress response http://purl.obolibrary.org/obo/GO_1903573 GO:0014742 biolink:BiologicalProcess positive regulation of muscle hypertrophy Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. go-plus.json http://purl.obolibrary.org/obo/GO_0014742 GO:1903572 biolink:BiologicalProcess positive regulation of protein kinase D signaling Any process that activates or increases the frequency, rate or extent of protein kinase D signaling. go-plus.json positive regulation of PKD signal transduction|up regulation of protein kinase D signaling cascade|upregulation of PKD signaling cascade|up-regulation of protein kinase D signalling cascade|activation of protein kinase D signaling|up-regulation of protein kinase D signaling|activation of protein kinase D signal transduction|up-regulation of protein kinase D signal transduction|upregulation of protein kinase D signalling cascade|upregulation of protein kinase D signaling cascade|up-regulation of PKD signal transduction|up regulation of PKD signaling cascade|positive regulation of PKD signaling cascade|up regulation of protein kinase D signaling|positive regulation of protein kinase D signal transduction|activation of PKD signaling cascade|up regulation of protein kinase D signal transduction|up-regulation of protein kinase D signaling cascade|upregulation of PKD signal transduction|up regulation of protein kinase D signalling cascade|positive regulation of protein kinase D signalling cascade|up-regulation of PKD signaling cascade|activation of protein kinase D signaling cascade|upregulation of protein kinase D signaling|activation of protein kinase D signalling cascade|upregulation of protein kinase D signal transduction|positive regulation of protein kinase D signaling cascade|up regulation of PKD signal transduction|activation of PKD signal transduction http://purl.obolibrary.org/obo/GO_1903572 GO:0014741 biolink:BiologicalProcess negative regulation of muscle hypertrophy Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. go-plus.json http://purl.obolibrary.org/obo/GO_0014741 GO:1903571 biolink:BiologicalProcess negative regulation of protein kinase D signaling Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling. go-plus.json downregulation of protein kinase D signaling cascade|down regulation of PKD signaling cascade|negative regulation of PKD signal transduction|down-regulation of PKD signal transduction|inhibition of protein kinase D signalling cascade|down regulation of protein kinase D signaling cascade|downregulation of PKD signaling cascade|down-regulation of protein kinase D signaling|inhibition of PKD signal transduction|negative regulation of protein kinase D signal transduction|down regulation of protein kinase D signalling cascade|down-regulation of protein kinase D signal transduction|inhibition of protein kinase D signaling cascade|down-regulation of PKD signaling cascade|negative regulation of PKD signaling cascade|downregulation of protein kinase D signalling cascade|downregulation of protein kinase D signaling|downregulation of protein kinase D signal transduction|down regulation of protein kinase D signaling|down regulation of PKD signal transduction|inhibition of protein kinase D signaling|negative regulation of protein kinase D signalling cascade|down regulation of protein kinase D signal transduction|down-regulation of protein kinase D signalling cascade|negative regulation of protein kinase D signaling cascade|down-regulation of protein kinase D signaling cascade|downregulation of PKD signal transduction|inhibition of protein kinase D signal transduction|inhibition of PKD signaling cascade http://purl.obolibrary.org/obo/GO_1903571 GO:0014740 biolink:BiologicalProcess negative regulation of muscle hyperplasia Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia. go-plus.json http://purl.obolibrary.org/obo/GO_0014740 GO:1903570 biolink:BiologicalProcess regulation of protein kinase D signaling Any process that modulates the frequency, rate or extent of protein kinase D signaling. go-plus.json regulation of protein kinase D signaling cascade|regulation of PKD signaling cascade|regulation of protein kinase D signalling cascade|regulation of protein kinase D signal transduction|regulation of PKD signal transduction http://purl.obolibrary.org/obo/GO_1903570 GO:0014746 biolink:BiologicalProcess regulation of tonic skeletal muscle contraction Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014746 GO:0014745 biolink:BiologicalProcess negative regulation of muscle adaptation Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. go-plus.json negative regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014745 GO:0014744 biolink:BiologicalProcess positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of muscle adaptation. go-plus.json positive regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014744 GO:0014743 biolink:BiologicalProcess regulation of muscle hypertrophy Any process that modulates the frequency, rate or extent of muscle hypertrophy. go-plus.json http://purl.obolibrary.org/obo/GO_0014743 GO:0048170 biolink:BiologicalProcess positive regulation of long-term neuronal synaptic plasticity A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. go-plus.json up regulation of long-term neuronal synaptic plasticity|upregulation of long-term neuronal synaptic plasticity|stimulation of long-term neuronal synaptic plasticity|up-regulation of long-term neuronal synaptic plasticity|activation of long-term neuronal synaptic plasticity http://purl.obolibrary.org/obo/GO_0048170 GO:0000109 biolink:CellularComponent nucleotide-excision repair complex Any complex formed of proteins that act in nucleotide-excision repair. go-plus.json UvrB-UvrC complex|UvrBC complex http://purl.obolibrary.org/obo/GO_0000109 goslim_pir CHEBI:38264 biolink:ChemicalSubstance 2-amino-3-methylpentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38264 GO:0000108 biolink:CellularComponent obsolete repairosome OBSOLETE. A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage. go-plus.json repairosome http://purl.obolibrary.org/obo/GO_0000108 CHEBI:38263 biolink:ChemicalSubstance 2-amino-3-hydroxybutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38263 CHEBI:38262 biolink:ChemicalSubstance allothreonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38262 GO:0000107 biolink:MolecularActivity imidazoleglycerol-phosphate synthase activity Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+). MetaCyc:GLUTAMIDOTRANS-RXN|RHEA:24793 go-plus.json imidazole-glycerol-phosphate synthase activity|glutamine amidotransferase:cyclase activity|imidazoleglycerol phosphate synthase activity|imidazole glycerol phosphate synthase activity http://purl.obolibrary.org/obo/GO_0000107 CHEBI:38261 biolink:ChemicalSubstance imidazolidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38261 GO:0000106 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000106 CHEBI:38266 biolink:ChemicalSubstance O-beta-D-glucosyl-trans-zeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38266 chebi_ph7_3 CHEBI:38265 biolink:ChemicalSubstance carvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38265 chebi_ph7_3 GO:0000112 biolink:CellularComponent nucleotide-excision repair factor 3 complex One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p). go-plus.json NEF3 complex http://purl.obolibrary.org/obo/GO_0000112 GO:0048178 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048178 GO:0000111 biolink:CellularComponent nucleotide-excision repair factor 2 complex One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p. go-plus.json NEF2 complex http://purl.obolibrary.org/obo/GO_0000111 GO:0048177 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048177 GO:0000110 biolink:CellularComponent nucleotide-excision repair factor 1 complex One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively. go-plus.json XPA-ERCC1-ERCC4 complex|NEF1 complex http://purl.obolibrary.org/obo/GO_0000110 GO:0048176 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048176 GO:0048175 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048175 GO:0048174 biolink:BiologicalProcess negative regulation of short-term neuronal synaptic plasticity A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. go-plus.json inhibition of short-term neuronal synaptic plasticity|down regulation of short-term neuronal synaptic plasticity|downregulation of short-term neuronal synaptic plasticity|down-regulation of short-term neuronal synaptic plasticity http://purl.obolibrary.org/obo/GO_0048174 GO:0000116 biolink:BiologicalProcess obsolete regulation of transcription involved in G2-phase of mitotic cell cycle OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G2 phase of the mitotic cell cycle. go-plus.json regulation of transcription from RNA polymerase II during G2-phase of mitotic cell cycle|regulation of transcription involved in G2-phase of mitotic cell cycle|G2-specific transcription in mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000116 GO:0000115 biolink:BiologicalProcess obsolete regulation of transcription involved in S phase of mitotic cell cycle OBSOLETE. A cell cycle process that regulates transcription such that the target genes are transcribed as part of the S phase of the mitotic cell cycle. go-plus.json S-specific transcription in mitotic cell cycle|regulation of transcription involved in S phase of mitotic cell cycle|regulation of transcription involved in S-phase of mitotic cell cycle|S-phase-specific transcription in mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during S-phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000115 GO:0048173 biolink:BiologicalProcess positive regulation of short-term neuronal synaptic plasticity A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. go-plus.json up-regulation of short-term neuronal synaptic plasticity|upregulation of short-term neuronal synaptic plasticity|up regulation of short-term neuronal synaptic plasticity|activation of short-term neuronal synaptic plasticity|stimulation of short-term neuronal synaptic plasticity http://purl.obolibrary.org/obo/GO_0048173 GO:0000114 biolink:BiologicalProcess obsolete regulation of transcription involved in G1 phase of mitotic cell cycle OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G1 phase of the mitotic cell cycle. go-plus.json regulation of transcription involved in G1 phase of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during G1 phase of cell cycle|G1-specific transcription in mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000114 GO:0048172 biolink:BiologicalProcess regulation of short-term neuronal synaptic plasticity A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. go-plus.json http://purl.obolibrary.org/obo/GO_0048172 GO:0048171 biolink:BiologicalProcess negative regulation of long-term neuronal synaptic plasticity A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. go-plus.json downregulation of long-term neuronal synaptic plasticity|down regulation of long-term neuronal synaptic plasticity|inhibition of long-term neuronal synaptic plasticity|down-regulation of long-term neuronal synaptic plasticity http://purl.obolibrary.org/obo/GO_0048171 GO:0000113 biolink:CellularComponent nucleotide-excision repair factor 4 complex One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p. go-plus.json NEF4 complex http://purl.obolibrary.org/obo/GO_0000113 CHEBI:133406 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-lysyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133406 chebi_ph7_3 CHEBI:133405 biolink:ChemicalSubstance L-methionyl-L-threonyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133405 chebi_ph7_3 CHEBI:133408 biolink:ChemicalSubstance 13,14-dihydro-15-oxoprostaglandin E1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133408 chebi_ph7_3 GO:1903579 biolink:BiologicalProcess negative regulation of ATP metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process. go-plus.json down-regulation of ATP metabolic process|downregulation of ATP metabolism|down regulation of ATP metabolism|inhibition of ATP metabolism|inhibition of ATP metabolic process|down regulation of ATP metabolic process|downregulation of ATP metabolic process|down-regulation of ATP metabolism|negative regulation of ATP metabolism http://purl.obolibrary.org/obo/GO_1903579 CHEBI:133407 biolink:ChemicalSubstance L-methionyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133407 chebi_ph7_3 GO:1903578 biolink:BiologicalProcess regulation of ATP metabolic process Any process that modulates the frequency, rate or extent of ATP metabolic process. go-plus.json regulation of ATP metabolism http://purl.obolibrary.org/obo/GO_1903578 GO:1903577 biolink:BiologicalProcess cellular response to L-arginine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903577 GO:1903576 biolink:BiologicalProcess response to L-arginine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903576 CHEBI:133409 biolink:ChemicalSubstance 15-oxoprostaglandin F2alpha(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133409 chebi_ph7_3 GO:1903575 biolink:BiologicalProcess cornified envelope assembly The aggregation, arrangement and bonding together of a set of components to form a cornified envelope. go-plus.json cornified envelope formation http://purl.obolibrary.org/obo/GO_1903575 GO:1903574 biolink:BiologicalProcess negative regulation of cellular response to amino acid starvation Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation. go-plus.json inhibition of cellular response to amino acid starvation|down-regulation of cellular response to amino acid starvation|downregulation of cellular response to amino acid starvation|down regulation of cellular response to amino acid starvation http://purl.obolibrary.org/obo/GO_1903574 GO:0048179 biolink:CellularComponent activin receptor complex A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed. go-plus.json http://purl.obolibrary.org/obo/GO_0048179 GO:1903584 biolink:BiologicalProcess regulation of histone deubiquitination Any process that modulates the frequency, rate or extent of histone deubiquitination. go-plus.json regulation of histone deubiquitylation|regulation of histone deubiquitinylation http://purl.obolibrary.org/obo/GO_1903584 GO:1903583 biolink:BiologicalProcess positive regulation of basophil degranulation Any process that activates or increases the frequency, rate or extent of basophil degranulation. go-plus.json up regulation of basophil degranulation|upregulation of basophil degranulation|up-regulation of basophil degranulation|activation of basophil degranulation http://purl.obolibrary.org/obo/GO_1903583 GO:1903582 biolink:BiologicalProcess negative regulation of basophil degranulation Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation. go-plus.json downregulation of basophil degranulation|down regulation of basophil degranulation|inhibition of basophil degranulation|down-regulation of basophil degranulation http://purl.obolibrary.org/obo/GO_1903582 CHEBI:133400 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-seryl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133400 chebi_ph7_3 GO:1903581 biolink:BiologicalProcess regulation of basophil degranulation Any process that modulates the frequency, rate or extent of basophil degranulation. go-plus.json http://purl.obolibrary.org/obo/GO_1903581 GO:1903580 biolink:BiologicalProcess positive regulation of ATP metabolic process Any process that activates or increases the frequency, rate or extent of ATP metabolic process. go-plus.json upregulation of ATP metabolic process|up-regulation of ATP metabolism|activation of ATP metabolism|up regulation of ATP metabolic process|positive regulation of ATP metabolism|activation of ATP metabolic process|up regulation of ATP metabolism|up-regulation of ATP metabolic process|upregulation of ATP metabolism http://purl.obolibrary.org/obo/GO_1903580 CHEBI:133402 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-valyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133402 chebi_ph7_3 CHEBI:133401 biolink:ChemicalSubstance L-methionyl-L-seryl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133401 chebi_ph7_3 CHEBI:133404 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-threonyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133404 chebi_ph7_3 CHEBI:133403 biolink:ChemicalSubstance L-methionyl-L-valyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133403 chebi_ph7_3 GO:0048181 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048181 CHEBI:38275 biolink:ChemicalSubstance pyrrolidinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38275 GO:0000119 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000119 GO:0048180 biolink:CellularComponent activin complex A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0048180 goslim_pir GO:0000118 biolink:CellularComponent histone deacetylase complex A protein complex that possesses histone deacetylase activity. go-plus.json HDAC complex http://purl.obolibrary.org/obo/GO_0000118 GO:0000117 biolink:BiologicalProcess regulation of transcription involved in G2/M transition of mitotic cell cycle Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle. go-plus.json regulation of transcription from RNA polymerase II promoter during G2/M transition of mitotic cell cycle|G2/M-specific transcription in mitotic cell cycle http://purl.obolibrary.org/obo/GO_0000117 NCBITaxon:Union_0000002 biolink:OrganismalEntity Viridiplantae or Cyanobacteria The union of the taxa Viridiplantae and Cyanobacteria. go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000002 CHEBI:77858 biolink:ChemicalSubstance 4-hydroxycoumarin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77858 chebi_ph7_3 CHEBI:77857 biolink:ChemicalSubstance cyanidin 3-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77857 chebi_ph7_3 NCBITaxon:Union_0000004 biolink:OrganismalEntity Prokaryota go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000004 NCBITaxon:Union_0000003 biolink:OrganismalEntity Myxininae or Petromyzontidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000003 NCBITaxon:Union_0000006 biolink:OrganismalEntity Viridiplantae or Archaea or Bacteria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000006 NCBITaxon:Union_0000005 biolink:OrganismalEntity obsolete Nematoda or Protostomia go-plus.json Invertebrata http://purl.obolibrary.org/obo/NCBITaxon_Union_0000005 NCBITaxon:Union_0000008 biolink:OrganismalEntity Viridiplantae or Euglenozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000008 CHEBI:77859 biolink:ChemicalSubstance 2-ammoniomuconate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77859 chebi_ph7_3 NCBITaxon:Union_0000007 biolink:OrganismalEntity Viridiplantae or Bacteria or Euglenozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000007 CHEBI:63212 biolink:ChemicalSubstance 2-hydroxy-dAMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63212 chebi_ph7_3 CHEBI:63211 biolink:ChemicalSubstance 2-hydroxy-dAMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_63211 CHEBI:63217 biolink:ChemicalSubstance 5(S),8(R)-DiHODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63217 chebi_ph7_3 CHEBI:63216 biolink:ChemicalSubstance 5(S),8(R)-DiHODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63216 PR:000001423 biolink:Protein histamine H2 receptor A histamine receptor that is a translation product of the human HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects. go-plus.json HH2R|H2 histamine receptor|gastric receptor I|HRH2|H2R http://purl.obolibrary.org/obo/PR_000001423 PR:000001422 biolink:Protein histamine H1 receptor A histamine receptor that is a translation product of the human HRH1 gene or a 1:1 ortholog thereof. go-plus.json H1 histamine receptor|HH1R|Bphs|HRH1|H1R http://purl.obolibrary.org/obo/PR_000001422 PR:000001426 biolink:Protein KiSS-1 receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human KISS1R gene or a 1:1 ortholog thereof. The preferred ligands are peptides of 10-54 residues derived from the metastasis-suppressor KiSS-1 protein. go-plus.json GPR54|KISS1R|hypogonadotropin-1|AXOR12|metastin receptor|KiSS-1R|OT7T175|G-protein coupled receptor OT7T175|kisspeptins receptor|G-protein coupled receptor 54 http://purl.obolibrary.org/obo/PR_000001426 CHEBI:77853 biolink:ChemicalSubstance persistent organic pollutant go-plus.json http://purl.obolibrary.org/obo/CHEBI_77853 CHEBI:77852 biolink:ChemicalSubstance 9(S)-HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77852 chebi_ph7_3 CHEBI:77851 biolink:ChemicalSubstance (2S)-2-ammonio-3-oxo-4-(phosphonatooxy)butanoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77851 chebi_ph7_3 CHEBI:77869 biolink:ChemicalSubstance (E,E)-sorbate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77869 chebi_ph7_3 CHEBI:63220 biolink:ChemicalSubstance 8-oxo-dGTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_63220 CHEBI:63224 biolink:ChemicalSubstance 8-oxo-dGMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63224 chebi_ph7_3 CHEBI:63223 biolink:ChemicalSubstance 8-oxo-dGMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_63223 CHEBI:63222 biolink:ChemicalSubstance 8-oxo-dGTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63222 PR:000001431 biolink:Protein N-formyl peptide receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human FPR1, FPR2, or FPR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds N-formyl methionyl peptides. go-plus.json formylpeptide receptor http://purl.obolibrary.org/obo/PR_000001431 CHEBI:77860 biolink:ChemicalSubstance 3-cyano-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77860 chebi_ph7_3 PR:000001439 biolink:Protein adenosine receptor protein A rhodopsin-like G-protein coupled receptor that is a translation product of the human ADORA1, ADORA2A, ADORA2B, or ADORA3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds adenosine. go-plus.json http://purl.obolibrary.org/obo/PR_000001439 NCBITaxon:Union_0000000 biolink:OrganismalEntity Viridiplantae or Bacteria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000000 CHEBI:77862 biolink:ChemicalSubstance gossypetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77862 chebi_ph7_3 NCBITaxon:Union_0000024 biolink:OrganismalEntity Unikonta The unikonts have a triple-gene fusion that is lacking in the bikonts. The three genes that are fused together in the unikonts but not bacteria or bikonts encode enzymes for synthesis of the pyrimidine nucleotides: carbamoyl phosphate synthase, dihydroorotase, aspartate carbamoyltransferase. This must have involved a double fusion, a rare pair of events, supporting the shared ancestry of Opisthokonta and Amoebozoa. go-plus.json unikonts http://purl.obolibrary.org/obo/NCBITaxon_Union_0000024 NCBITaxon:Union_0000023 biolink:OrganismalEntity Fungi or Bacteria or Archaea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000023 CHEBI:77877 biolink:ChemicalSubstance 3,3'-biflaviolin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77877 chebi_ph7_3 NCBITaxon:Union_0000025 biolink:OrganismalEntity Archaea or Eukaryota go-plus.json archaea-eukaryota http://purl.obolibrary.org/obo/NCBITaxon_Union_0000025 CHEBI:87200 biolink:ChemicalSubstance dicarboximide antifungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_87200 CHEBI:63239 biolink:ChemicalSubstance (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63239 chebi_ph7_3 CHEBI:63238 biolink:ChemicalSubstance (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63238 CHEBI:63237 biolink:ChemicalSubstance (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63237 CHEBI:77872 biolink:ChemicalSubstance precorrin-6A(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77872 chebi_ph7_3 CHEBI:77871 biolink:ChemicalSubstance precorrin-5(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77871 chebi_ph7_3 CHEBI:77870 biolink:ChemicalSubstance precorrin-3B(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77870 chebi_ph7_3 CHEBI:77876 biolink:ChemicalSubstance biochanin A 7-O-beta-D-glucoside 6''-O-malonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77876 chebi_ph7_3 NCBITaxon:Union_0000031 biolink:OrganismalEntity Stramenopiles or Cryptophyta go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000031 CHEBI:77875 biolink:ChemicalSubstance iminoaspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77875 chebi_ph7_3 NCBITaxon:Union_0000030 biolink:OrganismalEntity cellular organisms or viruses go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000030 CHEBI:77874 biolink:ChemicalSubstance hydrogenobyrinic acid a,c-diamide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77874 chebi_ph7_3 CHEBI:77873 biolink:ChemicalSubstance hydrogenobyrinate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77873 chebi_ph7_3 CHEBI:77889 biolink:ChemicalSubstance N-[omega-(9R)-hydroperoxy(10E,12Z)-octadecadienoyloxy]acylsphin-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77889 chebi_ph7_3 CHEBI:77888 biolink:ChemicalSubstance N-[omega-(linoleoyloxy)]acylsphin-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77888 chebi_ph7_3 CHEBI:63241 biolink:ChemicalSubstance (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63241 chebi_ph7_3 CHEBI:63245 biolink:ChemicalSubstance 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_63245 chebi_ph7_3 CHEBI:63244 biolink:ChemicalSubstance pentalen-13-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_63244 chebi_ph7_3 CHEBI:63243 biolink:ChemicalSubstance pentalen-13-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63243 chebi_ph7_3 CHEBI:63249 biolink:ChemicalSubstance (Z)-2-methylureidoperacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63249 chebi_ph7_3 CHEBI:63248 biolink:ChemicalSubstance oxidising agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_63248 CHEBI:63247 biolink:ChemicalSubstance reducing agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_63247 CHEBI:77881 biolink:ChemicalSubstance EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77881 NCBITaxon:Union_0000020 biolink:OrganismalEntity Fungi or Bacteria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000020 CHEBI:77887 biolink:ChemicalSubstance delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77887 chebi_ph7_3 CHEBI:77886 biolink:ChemicalSubstance demethylsulochrin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77886 chebi_ph7_3 CHEBI:77885 biolink:ChemicalSubstance nocardicin E(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77885 chebi_ph7_3 NCBITaxon:Union_0000022 biolink:OrganismalEntity Fungi or Dictyostelium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000022 NCBITaxon:Union_0000021 biolink:OrganismalEntity Viridiplantae or Bacteria or Euglenozoa or Archaea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_Union_0000021 CHEBI:77899 biolink:ChemicalSubstance (S)-averantin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77899 chebi_ph7_3 CHEBI:63253 biolink:ChemicalSubstance 3-oxo-5,6-dehydrosuberyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63253 CHEBI:63252 biolink:ChemicalSubstance 2-oxepin-2(3H)-ylideneacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63252 chebi_ph7_3 CHEBI:63251 biolink:ChemicalSubstance 2-oxepin-2(3H)-ylideneacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63251 PR:000025433 biolink:Protein nodal protein proteolytic cleavage product A nodal protein that has been processed by proteolytic cleavage. go-plus.json NODAL/ClvPrd http://purl.obolibrary.org/obo/PR_000025433 CHEBI:63250 biolink:ChemicalSubstance (Z)-2-methyl-3-aminoperacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63250 chebi_ph7_3 CHEBI:63257 biolink:ChemicalSubstance 3,8-dioxooct-5-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63257 chebi_ph7_3 CHEBI:63256 biolink:ChemicalSubstance 3,8-dioxooct-5-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63256 CHEBI:63255 biolink:ChemicalSubstance 3-oxo-5,6-dehydrosuberyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63255 chebi_ph7_3 CHEBI:133497 biolink:ChemicalSubstance 3-(2-methylthioethyl)malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133497 chebi_ph7_3 CHEBI:87228 biolink:ChemicalSubstance sulfonamide antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_87228 CHEBI:133496 biolink:ChemicalSubstance 3-(omega-methylthio)alkylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133496 chebi_ph7_3 PR:000001463 biolink:Protein glycoprotein hormone receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human FSHR, LHCGR, or TSHR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds glycoprotein hormones (thyrotropin, follitropin, lutropin, choriogonadotropin). go-plus.json http://purl.obolibrary.org/obo/PR_000001463 CHEBI:133499 biolink:ChemicalSubstance 2-(2-methylthio)ethylmaleate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133499 chebi_ph7_3 CHEBI:133498 biolink:ChemicalSubstance 2-(omega-methylthio)alkylmaleate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133498 chebi_ph7_3 CHEBI:77890 biolink:ChemicalSubstance 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77890 chebi_ph7_3 PR:000001464 biolink:Protein gonadotropin-releasing hormone receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human GNRHR or GNRHR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds gonadotropin-releasing hormone I or II. go-plus.json http://purl.obolibrary.org/obo/PR_000001464 CHEBI:77894 biolink:ChemicalSubstance aci-nitroethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_77894 chebi_ph7_3 PR:000001468 biolink:Protein intercellular adhesion molecule 3 An intercellular adhesion molecule 1/3 that is a translation product of the human ICAM3 gene or a 1:1 ortholog thereof. go-plus.json CD50|CDw50|ICAM3|ICAM-3|ICAM-R http://purl.obolibrary.org/obo/PR_000001468 CHEBI:77893 biolink:ChemicalSubstance 3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77893 chebi_ph7_3 CHEBI:133491 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133491 chebi_ph7_3 CHEBI:133490 biolink:ChemicalSubstance saturated fatty acyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133490 chebi_ph7_3 CHEBI:77891 biolink:ChemicalSubstance N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]sphing-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77891 chebi_ph7_3 CHEBI:133493 biolink:ChemicalSubstance omega-(methylthio)-2-oxocarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133493 chebi_ph7_3 CHEBI:133492 biolink:ChemicalSubstance polyunsaturated dicarboxylic acid dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133492 chebi_ph7_3 CHEBI:77897 biolink:ChemicalSubstance 2-hydroxy-dATP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77897 chebi_ph7_3 CHEBI:77896 biolink:ChemicalSubstance 8-oxo-dGTP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77896 chebi_ph7_3 CHEBI:77895 biolink:ChemicalSubstance 9(R)-HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77895 chebi_ph7_3 CHEBI:133494 biolink:ChemicalSubstance 2-(omega-methylthio)alkylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133494 chebi_ph7_3 UBERON:0035371 biolink:AnatomicalEntity retroperitoneal lymph node A lymph node located in the retroperitoneal space. go-plus.json retroperitoneal node http://purl.obolibrary.org/obo/UBERON_0035371 CHEBI:63260 biolink:ChemicalSubstance dTDP-alpha-D-desosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63260 chebi_ph7_3 CHEBI:63264 biolink:ChemicalSubstance dTDP-3-amino-3,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63264 CHEBI:63263 biolink:ChemicalSubstance beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63263 chebi_ph7_3 CHEBI:63262 biolink:ChemicalSubstance dTDP-3-azaniumyl-3,4,6-trideoxy-alpha-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63262 chebi_ph7_3 CHEBI:63268 biolink:ChemicalSubstance dTDP-alpha-D-mycaminose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63268 chebi_ph7_3 CHEBI:63267 biolink:ChemicalSubstance beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63267 chebi_ph7_3 CHEBI:63266 biolink:ChemicalSubstance 4-deoxy-Delta(4)-beta-D-GlcpA-(1->3)-beta-D-GalpNAc6S go-plus.json http://purl.obolibrary.org/obo/CHEBI_63266 CHEBI:87215 biolink:ChemicalSubstance N-terminal 5-oxo-L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87215 chebi_ph7_3 CHEBI:63265 biolink:ChemicalSubstance dTDP-3-azaniumyl-3,6-dideoxy-alpha-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63265 chebi_ph7_3 PR:000001472 biolink:Protein interleukin-19 A class 2 cytokine, IL-10 type that is a translation product of the human IL19 gene or a 1:1 ortholog thereof. go-plus.json NG.1|ZMDA1|melanoma differentiation-associated protein-like protein|IL-19|IL19 http://purl.obolibrary.org/obo/PR_000001472 PR:000001471 biolink:Protein interleukin-10 A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds. go-plus.json IL10|cytokine synthesis inhibitory factor|CSIF|IL-10 http://purl.obolibrary.org/obo/PR_000001471 PR:000001474 biolink:Protein interleukin-24 A class 2 cytokine, IL-10 type that is a translation product of the human IL24 gene or a 1:1 ortholog thereof. go-plus.json MDA7|IL24|melanoma differentiation-associated gene 7 protein|ST16|Th2-specific cytokine FISP|MDA-7|suppression of tumorigenicity 16 protein|IL-24|IL-4-induced secreted protein http://purl.obolibrary.org/obo/PR_000001474 PR:000001473 biolink:Protein interleukin-20 A class 2 cytokine, IL-10 type that is a translation product of the human IL20 gene or a 1:1 ortholog thereof. go-plus.json IL-20|ZCYTO10|IL20|cytokine Zcyto10 http://purl.obolibrary.org/obo/PR_000001473 NCBITaxon:169700 biolink:OrganismalEntity Coryphoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_169700 CHEBI:63269 biolink:ChemicalSubstance dTDP-3-dehydro-6-deoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63269 chebi_ph7_3 PR:000001475 biolink:Protein interleukin-26 A class 2 cytokine, IL-10 type that is a translation product of the human IL26 gene or a 1:1 ortholog thereof. go-plus.json IL26|AK155|IL-26|protein AK155 http://purl.obolibrary.org/obo/PR_000001475 GO:0000189 biolink:BiologicalProcess obsolete MAPK import into nucleus OBSOLETE. The directed movement of a MAP kinase to the nucleus upon activation. go-plus.json nuclear translocation of MAPK http://purl.obolibrary.org/obo/GO_0000189 GO:0000188 biolink:BiologicalProcess obsolete inactivation of MAPK activity OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase. go-plus.json termination of MAPK activity|inactivation of MAPK during sporulation http://purl.obolibrary.org/obo/GO_0000188 GO:0000187 biolink:BiologicalProcess obsolete activation of MAPK activity OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase (MAPK). go-plus.json MAPK activation|activation of MAP kinase|activation of MAPK activity during sporulation http://purl.obolibrary.org/obo/GO_0000187 GO:0000186 biolink:BiologicalProcess obsolete activation of MAPKK activity OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK). go-plus.json activation of MAP/ERK kinase kinase|activation of MAP2K activity|positive regulation of MAPKK activity|activation of MAPKK activity during sporulation|activation of MAP kinase kinase activity http://purl.obolibrary.org/obo/GO_0000186 CHEBI:63271 biolink:ChemicalSubstance 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_63271 CHEBI:63270 biolink:ChemicalSubstance N-acetyl-beta-D-galactosamine 6-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63270 chebi_ph7_3 UBERON:0035383 biolink:AnatomicalEntity lateral wall of nasopharynx go-plus.json lateral nasopharynx http://purl.obolibrary.org/obo/UBERON_0035383 GO:0000181 biolink:CellularComponent obsolete cytosolic small ribosomal subunit OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytosolic small ribosomal subunit http://purl.obolibrary.org/obo/GO_0000181 CHEBI:87242 biolink:ChemicalSubstance palmitoyllipid A go-plus.json http://purl.obolibrary.org/obo/CHEBI_87242 CHEBI:63275 biolink:ChemicalSubstance 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63275 GO:0000180 biolink:CellularComponent obsolete cytosolic large ribosomal subunit OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytosolic large ribosomal subunit http://purl.obolibrary.org/obo/GO_0000180 CHEBI:63274 biolink:ChemicalSubstance 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63274 chebi_ph7_3 CHEBI:63273 biolink:ChemicalSubstance UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63273 CHEBI:87244 biolink:ChemicalSubstance lipid IVB go-plus.json http://purl.obolibrary.org/obo/CHEBI_87244 GO:0000185 biolink:BiologicalProcess obsolete activation of MAPKKK activity OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK). go-plus.json activation of MAP3K activity|activation of MAP kinase kinase kinase|activation of MAPKKK activity during sporulation|positive regulation of MAP kinase kinase kinase activity|positive regulation of MAPKKK activity http://purl.obolibrary.org/obo/GO_0000185 GO:0000184 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, nonsense-mediated decay The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. Wikipedia:Nonsense-mediated_mRNA_decay|Wikipedia:Nonsense-mediated_decay go-plus.json mRNA breakdown, nonsense-mediated decay|mRNA degradation, nonsense-mediated decay|nonsense-mediated mRNA decay|mRNA catabolic process, nonsense-mediated|nuclear mRNA catabolic process, nonsense-mediated decay|mRNA catabolism, nonsense-mediated http://purl.obolibrary.org/obo/GO_0000184 CHEBI:87245 biolink:ChemicalSubstance lipid IIB go-plus.json http://purl.obolibrary.org/obo/CHEBI_87245 CHEBI:63278 biolink:ChemicalSubstance 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronic acid(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63278 chebi_ph7_3 GO:0000183 biolink:BiologicalProcess rDNA heterochromatin assembly The assembly of chromatin characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of rDNA. go-plus.json rDNA chromatin silencing|chromatin silencing at ribosomal DNA|heterochromatic silencing at rDNA|chromatin silencing at rDNA http://purl.obolibrary.org/obo/GO_0000183 CHEBI:63277 biolink:ChemicalSubstance UDP-2-acetamido-4-azaniumyl-2,4,6-trideoxy-alpha-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63277 chebi_ph7_3 GO:0000182 biolink:MolecularActivity rDNA binding Binding to a DNA sequence encoding a ribosomal RNA. go-plus.json ribosomal DNA binding http://purl.obolibrary.org/obo/GO_0000182 CHEBI:63276 biolink:ChemicalSubstance mycinamicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63276 CHEBI:133476 biolink:ChemicalSubstance hydantoin-5-propionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133476 chebi_ph7_3 CHEBI:133479 biolink:ChemicalSubstance S-(long-chain fatty acyl)-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133479 chebi_ph7_3 PR:000001442 biolink:Protein blood group Rh(D) polypeptide An erythrocyte membrane protein Rh that is a translation product of the human RHD gene or a 1:1 ortholog thereof. go-plus.json RhPII|CD240D|rhesus D antigen|RHD|Rh polypeptide 2|blood group RhD polypeptide|RHXIII http://purl.obolibrary.org/obo/PR_000001442 PR:000001449 biolink:Protein fibroblast growth factor receptor 2 A fibroblast growth factor receptor that is a translation product of the human FGFR2 gene or a 1:1 ortholog thereof. go-plus.json K-sam|Ect1|FGFR-2|CD332|KSAM|keratinocyte growth factor receptor|FGFR2|BEK|KGFR http://purl.obolibrary.org/obo/PR_000001449 CHEBI:133470 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133470 chebi_ph7_3 CHEBI:495505 biolink:ChemicalSubstance dATP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_495505 GO:0000199 biolink:BiologicalProcess obsolete activation of MAPK activity involved in cell wall organization or biogenesis OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. go-plus.json cell wall biogenesis, activation of MAPK activity|activation of MAPK activity involved in cell wall integrity|activation of MAPK activity involved in cell wall biogenesis http://purl.obolibrary.org/obo/GO_0000199 GO:0000198 biolink:BiologicalProcess obsolete activation of MAPKK activity involved in cell wall organization or biogenesis OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis. go-plus.json activation of MAPKK activity involved in cell wall integrity|activation of MAP kinase kinase activity during cell wall biogenesis|activation of MAPKK activity involved in cell wall biogenesis|cell wall biogenesis, activation of MAPKK activity|cell wall biogenesis, activation of MAP kinase kinase activity http://purl.obolibrary.org/obo/GO_0000198 GO:0000197 biolink:BiologicalProcess obsolete activation of MAPKKK activity involved in cell wall organization or biogenesis OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis. go-plus.json cell wall biogenesis, activation of MAP kinase kinase kinase activity|cell wall biogenesis, activation of MAPKKK activity|activation of MAPKKK activity involved in cell wall biogenesis|activation of MAPKKK activity involved in cell wall integrity|activation of MAP kinase kinase kinase activity during cell wall biogenesis http://purl.obolibrary.org/obo/GO_0000197 CHEBI:63282 biolink:ChemicalSubstance pseudaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63282 chebi_ph7_3 CHEBI:63281 biolink:ChemicalSubstance pseudaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63281 CHEBI:63280 biolink:ChemicalSubstance beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63280 chebi_ph7_3 GO:0000192 biolink:BiologicalProcess obsolete activation of MAPKK (pseudohyphal growth) OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth. go-plus.json activation of MAPKK (pseudohyphal growth) http://purl.obolibrary.org/obo/GO_0000192 CHEBI:63286 biolink:ChemicalSubstance dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63286 CHEBI:63285 biolink:ChemicalSubstance mycinamicin VI go-plus.json http://purl.obolibrary.org/obo/CHEBI_63285 GO:0000191 biolink:BiologicalProcess obsolete activation of MAPKKK (pseudohyphal growth) OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth. go-plus.json activation of MAPKKK (pseudohyphal growth) http://purl.obolibrary.org/obo/GO_0000191 CHEBI:87230 biolink:ChemicalSubstance nitrofuran antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_87230 GO:0000190 biolink:BiologicalProcess obsolete MAPKKK cascade (pseudohyphal growth) OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth. go-plus.json MAPKKK cascade (pseudohyphal growth) http://purl.obolibrary.org/obo/GO_0000190 CHEBI:63284 biolink:ChemicalSubstance mycinamicin IV go-plus.json http://purl.obolibrary.org/obo/CHEBI_63284 CHEBI:63283 biolink:ChemicalSubstance 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63283 chebi_ph7_3 UBERON:0035398 biolink:AnatomicalEntity branch of external carotid artery go-plus.json subdivision of external carotid artery|external carotid arterial subdivision http://purl.obolibrary.org/obo/UBERON_0035398 GO:0000196 biolink:BiologicalProcess cell wall integrity MAPK cascade A MAPK cascade that contributes to cell wall organization or biogenesis. go-plus.json PMK1-MAPK signal transduction pathway|Mpk1 cascade|cell wall biogenesis, MAPKKK cascade|Pmk1 MAPK cell integrity signaling|MAPKKK cascade involved in cell wall biogenesis|MAPK cascade involved in cell wall biogenesis|cell integrity MAPK pathway|MAPK cascade involved in cell wall organization or biogenesis|Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|Slt2 cascade http://purl.obolibrary.org/obo/GO_0000196 GO:0000195 biolink:BiologicalProcess obsolete nuclear translocation of MAPK (pseudohyphal growth) OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth. go-plus.json nuclear translocation of MAPK (pseudohyphal growth) http://purl.obolibrary.org/obo/GO_0000195 GO:0000194 biolink:BiologicalProcess obsolete inactivation of MAPK (pseudohyphal growth) OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth. go-plus.json inactivation of MAPK (pseudohyphal growth) http://purl.obolibrary.org/obo/GO_0000194 GO:0000193 biolink:BiologicalProcess obsolete activation of MAPK (pseudohyphal growth) OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth. go-plus.json activation of MAPK (pseudohyphal growth) http://purl.obolibrary.org/obo/GO_0000193 CHEBI:63287 biolink:ChemicalSubstance 3-amino-3,6-dideoxy-alpha-D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63287 PR:000001457 biolink:Protein galanin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human GALR1 to GALR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds the neuropeptide galanin. go-plus.json http://purl.obolibrary.org/obo/PR_000001457 CHEBI:28847 biolink:ChemicalSubstance D-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28847 CHEBI:28846 biolink:ChemicalSubstance dCDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28846 CHEBI:28843 biolink:ChemicalSubstance 5-amino-1-(5-phospho-D-ribosyl)imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_28843 CHEBI:28842 biolink:ChemicalSubstance octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28842 CHEBI:53800 biolink:ChemicalSubstance 4-hydroxy-2-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53800 chebi_ph7_3 CHEBI:28858 biolink:ChemicalSubstance 1D-myo-inositol 3,4-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28858 CHEBI:28857 biolink:ChemicalSubstance (Z)-hex-3-en-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28857 chebi_ph7_3 CHEBI:28859 biolink:ChemicalSubstance 5alpha-androstane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28859 chebi_ph7_3 CHEBI:28854 biolink:ChemicalSubstance 2,4-D go-plus.json http://purl.obolibrary.org/obo/CHEBI_28854 CHEBI:28853 biolink:ChemicalSubstance isopimpinellin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28853 chebi_ph7_3 CHEBI:28856 biolink:ChemicalSubstance p-toluate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28856 chebi_ph7_3 CHEBI:28855 biolink:ChemicalSubstance enterobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28855 CHEBI:28850 biolink:ChemicalSubstance dUDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28850 CHEBI:28852 biolink:ChemicalSubstance prostaglandin F1alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_28852 CHEBI:28851 biolink:ChemicalSubstance phenanthrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28851 chebi_ph7_3 GO:0097299 biolink:MolecularActivity obsolete cysteine-type endopeptidase activity involved in plant-type hypersensitive response OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen. go-plus.json metacaspase activity involved in plant-type hypersensitive response http://purl.obolibrary.org/obo/GO_0097299 GO:0097298 biolink:BiologicalProcess regulation of nucleus size Any process that modulates the size of the nucleus. go-plus.json regulation of nuclear volume|regulation of nuclear size http://purl.obolibrary.org/obo/GO_0097298 CHEBI:28824 biolink:ChemicalSubstance stigmasterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28824 chebi_ph7_3 CHEBI:28827 biolink:ChemicalSubstance sparteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28827 CHEBI:28826 biolink:ChemicalSubstance fluoromethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28826 chebi_ph7_3 GO:0097295 biolink:BiologicalProcess morphine biosynthetic process The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. go-plus.json morphine biosynthesis|morphine anabolism|morphine synthesis|morphine formation http://purl.obolibrary.org/obo/GO_0097295 CHEBI:28821 biolink:ChemicalSubstance piperine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28821 chebi_ph7_3 GO:0097294 biolink:BiologicalProcess 'de novo' XMP biosynthetic process The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors. go-plus.json 'de novo' XMP synthesis|'de novo' XMP formation|'de novo' XMP biosynthesis|'de novo' XMP anabolism http://purl.obolibrary.org/obo/GO_0097294 GO:0097297 biolink:BiologicalProcess activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis. go-plus.json activation of effector caspase activity http://purl.obolibrary.org/obo/GO_0097297 CHEBI:28823 biolink:ChemicalSubstance 2'-deoxyinosine-5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28823 GO:0097296 biolink:BiologicalProcess activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway. go-plus.json activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|activation of initiator caspase activity http://purl.obolibrary.org/obo/GO_0097296 CHEBI:28822 biolink:ChemicalSubstance icosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28822 GO:0097291 biolink:BiologicalProcess renal phosphate ion absorption A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. go-plus.json renal phosphate absorption http://purl.obolibrary.org/obo/GO_0097291 GO:0097290 biolink:BiologicalProcess alpha-ribazole biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12). go-plus.json alpha-ribazole formation|alpha-ribazole biosynthesis|alpha-ribazole anabolism|alpha-ribazole synthesis http://purl.obolibrary.org/obo/GO_0097290 GO:0097293 biolink:BiologicalProcess XMP biosynthetic process The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate. go-plus.json XMP anabolism|XMP biosynthesis|XMP synthesis|XMP formation http://purl.obolibrary.org/obo/GO_0097293 GO:0097292 biolink:BiologicalProcess XMP metabolic process The chemical reactions and pathways involving XMP, xanthosine monophosphate. go-plus.json XMP metabolism http://purl.obolibrary.org/obo/GO_0097292 CHEBI:14216 biolink:ChemicalSubstance erythrulose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_14216 CHEBI:28829 biolink:ChemicalSubstance aminophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28829 CHEBI:77803 biolink:ChemicalSubstance 2-ammonio-3-(3-oxoprop-1-enyl)but-2-enedioate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77803 chebi_ph7_3 CHEBI:28835 biolink:ChemicalSubstance testosterone 17-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28835 CHEBI:77802 biolink:ChemicalSubstance uridine 2'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77802 chebi_ph7_3 CHEBI:28838 biolink:ChemicalSubstance lutein go-plus.json http://purl.obolibrary.org/obo/CHEBI_28838 chebi_ph7_3 CHEBI:28837 biolink:ChemicalSubstance octanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28837 CHEBI:77800 biolink:ChemicalSubstance 2'-hydroxydaidzein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77800 chebi_ph7_3 CHEBI:28831 biolink:ChemicalSubstance propan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28831 chebi_ph7_3 CHEBI:77805 biolink:ChemicalSubstance enterobactin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77805 chebi_ph7_3 CHEBI:28834 biolink:ChemicalSubstance deoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28834 UBERON:0035471 biolink:AnatomicalEntity posterior surface of kidney go-plus.json facies posterior renis|facies posterior (Ren) http://purl.obolibrary.org/obo/UBERON_0035471 CHEBI:28833 biolink:ChemicalSubstance gibberellin A3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28833 CHEBI:77804 biolink:ChemicalSubstance biochanin A 7-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77804 chebi_ph7_3 CHEBI:28839 biolink:ChemicalSubstance 3-disulfanyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28839 CHEBI:28803 biolink:ChemicalSubstance pyridoxine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28803 CHEBI:28802 biolink:ChemicalSubstance flavonols go-plus.json http://purl.obolibrary.org/obo/CHEBI_28802 chebi_ph7_3 CHEBI:77812 biolink:ChemicalSubstance 9-oxononanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77812 chebi_ph7_3 CHEBI:28804 biolink:ChemicalSubstance D-2-aminopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28804 CHEBI:77811 biolink:ChemicalSubstance 1-acyl-2-hexadecenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77811 chebi_ph7_3 CHEBI:28800 biolink:ChemicalSubstance N-acetylgalactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28800 UBERON:0035401 biolink:AnatomicalEntity posterior wall of nasopharynx go-plus.json posterior nasopharynx http://purl.obolibrary.org/obo/UBERON_0035401 UBERON:0035403 biolink:AnatomicalEntity hypophysial artery An artery that supplies the pituitary gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035403 CHEBI:77810 biolink:ChemicalSubstance 2-16:1-lysophosphatidate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77810 chebi_ph7_3 CHEBI:28807 biolink:ChemicalSubstance dITP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28807 CHEBI:28806 biolink:ChemicalSubstance 2'-deoxyinosine-5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28806 CHEBI:28808 biolink:ChemicalSubstance mannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28808 CHEBI:77825 biolink:ChemicalSubstance luteolin 7-O-[(beta-D-glucosyluronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77825 chebi_ph7_3 CHEBI:28813 biolink:ChemicalSubstance sinapyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28813 chebi_ph7_3 CHEBI:77824 biolink:ChemicalSubstance cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77824 chebi_ph7_3 CHEBI:28815 biolink:ChemicalSubstance heparan sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28815 CHEBI:77828 biolink:ChemicalSubstance guanosine 3',5'-bis(diphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77828 chebi_ph7_3 CHEBI:28812 biolink:ChemicalSubstance (aminomethyl)phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28812 CHEBI:77827 biolink:ChemicalSubstance 2-arylethylammomium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77827 chebi_ph7_3 CHEBI:77826 biolink:ChemicalSubstance mugineate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77826 chebi_ph7_3 PR:000001631 biolink:Protein nociceptin receptor An opioid receptor protein that is a translation product of the human OPRL1 gene or a 1:1 ortholog thereof. The preferred ligand is nociceptin. go-plus.json OPRL1|Oprl|KOR-3|OOR|kappa-type 3 opioid receptor|ORL1|ORGC|orphanin FQ receptor|K3 opiate receptor http://purl.obolibrary.org/obo/PR_000001631 PR:000001635 biolink:Protein oxytocin receptor A vasopressin/oxytocin receptor that is a translation product of the human OXTR gene or a 1:1 ortholog thereof. The preferred ligand is oxytocin. go-plus.json OT-R|OXTR http://purl.obolibrary.org/obo/PR_000001635 CHEBI:28818 biolink:ChemicalSubstance (24R)-24,25-dihydroxycalciol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28818 chebi_ph7_3 CHEBI:28817 biolink:ChemicalSubstance dodecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28817 chebi_ph7_3 CHEBI:77836 biolink:ChemicalSubstance N-[omega-(acylyloxy)]acylsphin-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77836 chebi_ph7_3 CHEBI:77833 biolink:ChemicalSubstance 1-palmitoyl-2-valeroyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77833 chebi_ph7_3 CHEBI:77838 biolink:ChemicalSubstance delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77838 chebi_ph7_3 CHEBI:77832 biolink:ChemicalSubstance 1-palmitoyl-2-butanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77832 chebi_ph7_3 CHEBI:77831 biolink:ChemicalSubstance 1-palmitoyl-2-propionyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77831 chebi_ph7_3 CHEBI:77830 biolink:ChemicalSubstance 2-arachidonoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77830 chebi_ph7_3 CHEBI:77847 biolink:ChemicalSubstance glycerol 1-phosphodiester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77847 chebi_ph7_3 CHEBI:77846 biolink:ChemicalSubstance dehydroglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77846 chebi_ph7_3 CHEBI:77844 biolink:ChemicalSubstance delphinidin 3,3',5-tri-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77844 chebi_ph7_3 CHEBI:77848 biolink:ChemicalSubstance 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77848 chebi_ph7_3 UBERON:0035431 biolink:AnatomicalEntity mediastinal pleura The parietal pleura that lines the mediastinum. go-plus.json pars mediastinalis (pleurae)|mediastinal part of parietal pleura|pars mediastinalis pleurae parietalis http://purl.obolibrary.org/obo/UBERON_0035431 CHEBI:63202 biolink:ChemicalSubstance dTDP-D-ravidosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63202 UBERON:0035435 biolink:AnatomicalEntity right suprarenal vein A vein that drains blood from the right adrenal gland into the inferior vena cava. go-plus.json vena suprarenalis (adrenalis) dextra http://purl.obolibrary.org/obo/UBERON_0035435 CHEBI:63205 biolink:ChemicalSubstance (+)-gamma-cadinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63205 chebi_ph7_3 CHEBI:63203 biolink:ChemicalSubstance (-)-gamma-cadinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63203 chebi_ph7_3 CHEBI:63209 biolink:ChemicalSubstance 2-hydroxy-dATP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63209 CHEBI:63208 biolink:ChemicalSubstance 2-hydroxy-dATP go-plus.json http://purl.obolibrary.org/obo/CHEBI_63208 CHEBI:63207 biolink:ChemicalSubstance mycinamicin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_63207 PR:000001612 biolink:Protein mu-type opioid receptor An opioid receptor protein that is a translation product of the human OPRM1 gene or a 1:1 ortholog thereof. The preferred ligands are beta-endorphin and enkephalins. go-plus.json MOR1|mu opiate receptor|Oprm|OPRM1|mu-opioid receptor|MOR-1|MOP|Mor|M-OR-1|mu opioid receptor http://purl.obolibrary.org/obo/PR_000001612 CHEBI:77843 biolink:ChemicalSubstance thymidine 3'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77843 chebi_ph7_3 CHEBI:77842 biolink:ChemicalSubstance stipitatate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77842 chebi_ph7_3 CHEBI:77840 biolink:ChemicalSubstance 3,8'-biflaviolin 2,7,2'-triolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77840 chebi_ph7_3 GO:0097233 biolink:CellularComponent alveolar lamellar body membrane The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. go-plus.json http://purl.obolibrary.org/obo/GO_0097233 GO:0000321 biolink:BiologicalProcess re-entry into mitotic cell cycle after pheromone arrest The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0000321 GO:0097232 biolink:CellularComponent lamellar body membrane The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0097232 GO:0000320 biolink:BiologicalProcess re-entry into mitotic cell cycle The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state. go-plus.json http://purl.obolibrary.org/obo/GO_0000320 GO:0097235 biolink:BiologicalProcess obsolete positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0097235 CHEBI:14280 biolink:ChemicalSubstance formyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_14280 GO:0097234 biolink:CellularComponent epidermal lamellar body membrane The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. go-plus.json http://purl.obolibrary.org/obo/GO_0097234 GO:0000325 biolink:CellularComponent plant-type vacuole A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. go-plus.json vacuole, cell cycle-independent morphology http://purl.obolibrary.org/obo/GO_0000325 GO:0000324 biolink:CellularComponent fungal-type vacuole A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. go-plus.json vacuole, cell cycle-correlated morphology http://purl.obolibrary.org/obo/GO_0000324 GO:0097231 biolink:BiologicalProcess cell motility in response to calcium ion Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus. go-plus.json Ca2+ facilitation of cell motility|calcium ion facilitation of cell motility http://purl.obolibrary.org/obo/GO_0097231 GO:0000323 biolink:CellularComponent lytic vacuole A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. go-plus.json http://purl.obolibrary.org/obo/GO_0000323 GO:0097230 biolink:BiologicalProcess cell motility in response to potassium ion Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus. go-plus.json K+ facilitation of cell motility|potassium ion facilitation of cell motility http://purl.obolibrary.org/obo/GO_0097230 GO:0000322 biolink:CellularComponent storage vacuole A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0000322 GO:1903469 biolink:BiologicalProcess removal of RNA primer involved in mitotic DNA replication Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication. go-plus.json DNA replication, removal of RNA primer involved in mitotic nuclear cell cycle DNA replication|Okazaki initiator RNA removal involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|Okazaki initiator RNA removal involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication during S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in mitotic cell cycle DNA replication|Okazaki initiator RNA removal involved in DNA replication during S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S-phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in mitotic nuclear cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1903469 GO:1903468 biolink:BiologicalProcess positive regulation of DNA replication initiation Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. go-plus.json positive regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|activation of DNA replication initiation involved in mitotic cell cycle DNA replication|upregulation of DNA replication initiation involved in mitotic DNA replication|up-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|up-regulation of DNA replication initiation involved in mitotic DNA replication|activation of DNA replication initiation involved in mitotic DNA replication|upregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|up regulation of DNA replication initiation involved in mitotic DNA replication|up regulation of DNA replication initiation involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1903468 GO:1903467 biolink:BiologicalProcess negative regulation of mitotic DNA replication initiation Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. go-plus.json down regulation of DNA replication initiation involved in mitotic DNA replication|inhibition of DNA replication initiation involved in mitotic DNA replication|negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic DNA replication|down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|downregulation of DNA replication initiation involved in mitotic DNA replication http://purl.obolibrary.org/obo/GO_1903467 GO:1903466 biolink:BiologicalProcess regulation of mitotic DNA replication initiation Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. go-plus.json regulation of DNA replication initiation involved in mitotic cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1903466 GO:1903465 biolink:BiologicalProcess positive regulation of mitotic cell cycle DNA replication Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication. go-plus.json activation of DNA replication during S phase involved in mitotic cell cycle|upregulation of mitotic cell cycle DNA replication|upregulation of DNA replication involved in S-phase involved in mitotic cell cycle|positive regulation of DNA replication involved in S phase involved in mitotic cell cycle|up-regulation of DNA replication during S phase involved in mitotic cell cycle|upregulation of mitotic nuclear cell cycle DNA replication|up regulation of DNA replication involved in S phase involved in mitotic cell cycle|upregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up-regulation of mitotic cell cycle DNA replication|activation of mitotic cell cycle DNA replication|up-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|activation of DNA replication involved in S-phase involved in mitotic cell cycle|upregulation of DNA replication during S phase involved in mitotic cell cycle|up-regulation of mitotic nuclear cell cycle DNA replication|activation of mitotic nuclear cell cycle DNA replication|upregulation of DNA replication involved in S phase involved in mitotic cell cycle|up regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|positive regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of mitotic cell cycle DNA replication|positive regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up regulation of DNA replication during S phase involved in mitotic cell cycle|activation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up-regulation of DNA replication involved in S phase involved in mitotic cell cycle|positive regulation of mitotic nuclear cell cycle DNA replication|activation of DNA replication involved in S phase involved in mitotic cell cycle|positive regulation of DNA replication during S phase involved in mitotic cell cycle|up regulation of mitotic nuclear cell cycle DNA replication|up-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903465 GO:1903464 biolink:BiologicalProcess negative regulation of mitotic cell cycle DNA replication Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication. go-plus.json downregulation of mitotic nuclear cell cycle DNA replication|down regulation of DNA replication involved in S-phase involved in mitotic cell cycle|down-regulation of DNA replication involved in S phase involved in mitotic cell cycle|negative regulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of DNA replication involved in S-phase involved in mitotic cell cycle|inhibition of nuclear cell cycle DNA replication involved in mitotic cell cycle|down regulation of mitotic nuclear cell cycle DNA replication|inhibition of mitotic nuclear cell cycle DNA replication|downregulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of DNA replication during S phase involved in mitotic cell cycle|down regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down regulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of DNA replication involved in S phase involved in mitotic cell cycle|downregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of mitotic cell cycle DNA replication|down regulation of DNA replication during S phase involved in mitotic cell cycle|down-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|negative regulation of DNA replication involved in S-phase involved in mitotic cell cycle|downregulation of DNA replication during S phase involved in mitotic cell cycle|negative regulation of mitotic nuclear cell cycle DNA replication|down-regulation of mitotic nuclear cell cycle DNA replication|negative regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|downregulation of mitotic cell cycle DNA replication|downregulation of DNA replication involved in S-phase involved in mitotic cell cycle|down regulation of mitotic cell cycle DNA replication|negative regulation of DNA replication during S phase involved in mitotic cell cycle|inhibition of mitotic cell cycle DNA replication|down-regulation of DNA replication during S phase involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903464 GO:1903474 biolink:BiologicalProcess obsolete anchoring of the mitotic actomyosin contractile ring to the plasma membrane OBSOLETE. A process that maintains the mitotic actinomyosin contractile ring at the plasma membrane. go-plus.json maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|cytokinetic ring anchoring involved in mitotic cell cycle|maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903474 GO:1903473 biolink:BiologicalProcess positive regulation of mitotic actomyosin contractile ring contraction Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction. go-plus.json activation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|positive regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|upregulation of mitotic actomyosin contractile ring contraction|up-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up regulation of mitotic actomyosin contractile ring contraction|positive regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of mitotic actomyosin contractile ring contraction|up regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up-regulation of mitotic actomyosin contractile ring contraction|upregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of mitotic actomyosin contractile ring constriction|up regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903473 CHEBI:38249 biolink:ChemicalSubstance (1S,4R)-1-hydroxylimonen-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_38249 chebi_ph7_3 GO:1903472 biolink:BiologicalProcess negative regulation of mitotic actomyosin contractile ring contraction Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction. go-plus.json negative regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down regulation of mitotic actomyosin contractile ring contraction|downregulation of mitotic actomyosin contractile ring contraction|negative regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down-regulation of mitotic actomyosin contractile ring contraction|downregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|inhibition of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of mitotic actomyosin contractile ring contraction|negative regulation of mitotic actomyosin contractile ring constriction|downregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903472 GO:1903471 biolink:BiologicalProcess regulation of mitotic actomyosin contractile ring contraction Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction. go-plus.json regulation of mitotic actomyosin contractile ring constriction|regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903471 CHEBI:38247 biolink:ChemicalSubstance (R)-3-hydroxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38247 GO:1903470 biolink:BiologicalProcess obsolete actomyosin contractile ring assembly involved in mitotic cell cycle OBSOLETE. Any actomyosin contractile ring assembly that is involved in mitotic cell cycle. go-plus.json contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin ring formation involved in mitotic cell cycle|constriction ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring formation involved in mitotic cell cycle|cytokinesis, actomyosin ring biosynthesis involved in mitotic cell cycle|cytokinesis, contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring assembly involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903470 GO:0000329 biolink:CellularComponent fungal-type vacuole membrane The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. go-plus.json membrane of vacuole with cell cycle-correlated morphology|fungal-type vacuolar membrane http://purl.obolibrary.org/obo/GO_0000329 GO:0000328 biolink:CellularComponent fungal-type vacuole lumen The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae. go-plus.json lumen of vacuole with cell cycle-correlated morphology http://purl.obolibrary.org/obo/GO_0000328 GO:0000327 biolink:CellularComponent lytic vacuole within protein storage vacuole A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0000327 GO:0000326 biolink:CellularComponent protein storage vacuole A storage vacuole that contains a lytic vacuole; identified in plants. go-plus.json http://purl.obolibrary.org/obo/GO_0000326 GO:0097237 biolink:BiologicalProcess cellular response to toxic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097237 GO:0097236 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions. go-plus.json http://purl.obolibrary.org/obo/GO_0097236 GO:0097239 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097239 GO:0097238 biolink:BiologicalProcess cellular response to methylglyoxal Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. go-plus.json http://purl.obolibrary.org/obo/GO_0097238 CHEBI:14272 biolink:ChemicalSubstance fluoroacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_14272 chebi_ph7_3 GO:0097244 biolink:MolecularActivity flavonol binding Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone. go-plus.json http://purl.obolibrary.org/obo/GO_0097244 GO:0000332 biolink:MolecularActivity template for synthesis of G-rich strand of telomere DNA activity Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA. go-plus.json telomerase, template|telomerase RNA http://purl.obolibrary.org/obo/GO_0000332 GO:0000331 biolink:CellularComponent contractile vacuole A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory. Wikipedia:Contractile_vacuole go-plus.json central vacuole|central bladder http://purl.obolibrary.org/obo/GO_0000331 GO:0097243 biolink:MolecularActivity flavonoid binding Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge. go-plus.json http://purl.obolibrary.org/obo/GO_0097243 GO:0097246 biolink:MolecularActivity catechin binding Binding to a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure. go-plus.json http://purl.obolibrary.org/obo/GO_0097246 GO:0000330 biolink:CellularComponent plant-type vacuole lumen The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana. go-plus.json lumen of vacuole with cell cycle-independent morphology http://purl.obolibrary.org/obo/GO_0000330 GO:0097245 biolink:MolecularActivity flavanol binding Binding to a flavanol. go-plus.json flavan-3-ol binding http://purl.obolibrary.org/obo/GO_0097245 GO:0000336 biolink:BiologicalProcess positive regulation of transposition, DNA-mediated Any process that activates or increases the frequency, rate or extent of DNA transposition. go-plus.json up regulation of DNA transposition|activation of DNA transposition|stimulation of DNA transposition|up-regulation of DNA transposition|positive regulation of DNA transposition|upregulation of DNA transposition http://purl.obolibrary.org/obo/GO_0000336 GO:0097240 biolink:BiologicalProcess chromosome attachment to the nuclear envelope The process in which chromatin is anchored to the nuclear envelope. go-plus.json attachment of chromatin to nuclear envelope http://purl.obolibrary.org/obo/GO_0097240 CHEBI:38260 biolink:ChemicalSubstance pyrrolidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38260 GO:0000335 biolink:BiologicalProcess negative regulation of transposition, DNA-mediated Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition. go-plus.json down-regulation of DNA transposition|inhibition of DNA transposition|negative regulation of DNA transposition|down regulation of DNA transposition|downregulation of DNA transposition http://purl.obolibrary.org/obo/GO_0000335 GO:0000334 biolink:MolecularActivity 3-hydroxyanthranilate 3,4-dioxygenase activity Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). KEGG_REACTION:R02665|RHEA:17953|Reactome:R-HSA-71218|MetaCyc:1.13.11.6-RXN|EC:1.13.11.6|UM-BBD_reactionID:r1027 go-plus.json 3-hydroxyanthranilic oxygenase activity|3-hydroxyanthranilate oxygenase activity|3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)|3-hydroxyanthranilic acid dioxygenase activity|3HAO|3-hydroxyanthranilic acid oxygenase activity http://purl.obolibrary.org/obo/GO_0000334 GO:0097242 biolink:BiologicalProcess amyloid-beta clearance The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors. go-plus.json beta-amyloid clearance http://purl.obolibrary.org/obo/GO_0097242 GO:0097241 biolink:BiologicalProcess hematopoietic stem cell migration to bone marrow The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. go-plus.json hemopoietic stem cell migration to bone marrow|hematopoietic stem cell homing|progenitor cell homing http://purl.obolibrary.org/obo/GO_0097241 GO:0000333 biolink:CellularComponent telomerase catalytic core complex The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. go-plus.json TERT-TERC complex http://purl.obolibrary.org/obo/GO_0000333 CHEBI:133507 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133507 chebi_ph7_3 GO:1903479 biolink:BiologicalProcess mitotic actomyosin contractile ring assembly actin filament organization Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly. go-plus.json actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|actin filament organisation involved in mitotic actomyosin contractile ring assembly|actin filament organization involved in mitotic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1903479 CHEBI:133506 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133506 chebi_ph7_3 CHEBI:133509 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133509 chebi_ph7_3 GO:1903478 biolink:BiologicalProcess actin filament bundle convergence involved in mitotic contractile ring assembly Any actin filament bundle convergence that is involved in mitotic actomyosin contractile ring assembly. go-plus.json actin filament bundle convergence involved in contractile ring assembly involved in mitotic cytokinesis|actin filament bundle convergence involved in cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|actin filament bundle convergence involved in mitotic actomyosin contractile ring assembly|actin filament bundle convergence involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis http://purl.obolibrary.org/obo/GO_1903478 GO:1903477 biolink:BiologicalProcess mitotic contractile ring actin filament bundle assembly Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly. go-plus.json actin filament bundle assembly involved in mitotic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1903477 GO:1903476 biolink:BiologicalProcess protein localization to cell division site involved in mitotic actomyosin contractile ring assembly Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly. go-plus.json protein localization to cell division site involved in contractile ring assembly involved in mitotic cytokinesis|protein localisation to cell division site involved in mitotic actomyosin contractile ring assembly|protein localization to cell division site involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis http://purl.obolibrary.org/obo/GO_1903476 GO:1903475 biolink:BiologicalProcess mitotic actomyosin contractile ring assembly Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis. go-plus.json actomyosin contractile ring assembly involved in cytokinesis after mitosis|cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|contractile ring assembly involved in mitotic cytokinesis http://purl.obolibrary.org/obo/GO_1903475 GO:1903485 biolink:BiologicalProcess obsolete positive regulation of maintenance of mitotic actomyosin contractile ring localization OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization. go-plus.json positive regulation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|activation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of mitotic actomyosin contractile ring localization|upregulation of cytokinetic ring anchoring involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|upregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of mitotic actomyosin contractile ring localization|up regulation of cytokinetic ring anchoring involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903485 GO:1903484 biolink:BiologicalProcess obsolete negative regulation of maintenance of mitotic actomyosin contractile ring localization OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization. go-plus.json inhibition of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of mitotic actomyosin contractile ring localization|negative regulation of cytokinetic ring anchoring involved in mitotic cell cycle|downregulation of maintenance of mitotic actomyosin contractile ring localization|down-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of mitotic actomyosin contractile ring localization|inhibition of cytokinetic ring anchoring involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of mitotic actomyosin contractile ring localization|downregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|down regulation of cytokinetic ring anchoring involved in mitotic cell cycle|down regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of cytokinetic ring anchoring involved in mitotic cell cycle|down regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903484 GO:1903483 biolink:BiologicalProcess obsolete regulation of maintenance of mitotic actomyosin contractile ring localization OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization. go-plus.json regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinetic ring anchoring involved in mitotic cell cycle|regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903483 CHEBI:38259 biolink:ChemicalSubstance divinyl chlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_38259 GO:1903482 biolink:BiologicalProcess positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly Any process that activates or increases the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly. go-plus.json upregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|upregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|upregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|activation of actin filament organization involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|positive regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|up-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|positive regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1903482 GO:1903481 biolink:BiologicalProcess negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly Any process that stops, prevents or reduces the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly. go-plus.json downregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organisation involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|negative regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|inhibition of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|negative regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organization involved in mitotic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1903481 CHEBI:14268 biolink:ChemicalSubstance flavonol 3-O-glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_14268 chebi_ph7_3 CHEBI:133501 biolink:ChemicalSubstance 3-(3-methylthio)propylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133501 chebi_ph7_3 GO:1903480 biolink:BiologicalProcess regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly Any process that modulates the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly. go-plus.json regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis http://purl.obolibrary.org/obo/GO_1903480 CHEBI:133500 biolink:ChemicalSubstance 2-(2-methylthio)propylmaleate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133500 chebi_ph7_3 CHEBI:133503 biolink:ChemicalSubstance beta-D-GalpNAc-(1->4)-[alpha-Neup5Gc-(2->3)]-beta-D-Galp go-plus.json http://purl.obolibrary.org/obo/CHEBI_133503 CHEBI:38252 biolink:ChemicalSubstance phorbines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38252 GO:0000339 biolink:MolecularActivity RNA cap binding Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule. go-plus.json snRNA cap binding|binding to mRNA cap|mRNA cap binding http://purl.obolibrary.org/obo/GO_0000339 GO:0000338 biolink:BiologicalProcess protein deneddylation The removal of a ubiquitin-like protein of the NEDD8 type from a protein. go-plus.json cullin deneddylation http://purl.obolibrary.org/obo/GO_0000338 CHEBI:38251 biolink:ChemicalSubstance magnesium tetrapyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38251 GO:0000337 biolink:BiologicalProcess regulation of transposition, DNA-mediated Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule. go-plus.json regulation of DNA transposition http://purl.obolibrary.org/obo/GO_0000337 GO:0097248 biolink:BiologicalProcess maintenance of protein location in cell cortex of cell tip A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097248 CHEBI:38257 biolink:ChemicalSubstance pheophorbide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_38257 GO:0097247 biolink:MolecularActivity epigallocatechin 3-gallate binding Binding to epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin. go-plus.json catechin gallate binding|EGCG binding http://purl.obolibrary.org/obo/GO_0097247 CHEBI:14261 biolink:ChemicalSubstance feruloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_14261 CHEBI:38254 biolink:ChemicalSubstance pheophorbide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38254 GO:0097249 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097249 GO:0097211 biolink:BiologicalProcess cellular response to gonadotropin-releasing hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. go-plus.json cellular response to gonadotrophin-releasing hormone|cellular response to GnRH http://purl.obolibrary.org/obo/GO_0097211 NCBITaxon:2336 biolink:OrganismalEntity Thermotoga maritima go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2336 GO:0097210 biolink:BiologicalProcess response to gonadotropin-releasing hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. go-plus.json response to GnRH http://purl.obolibrary.org/obo/GO_0097210 NCBITaxon:2335 biolink:OrganismalEntity Thermotoga go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2335 GO:0097213 biolink:BiologicalProcess regulation of lysosomal membrane permeability Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane. go-plus.json regulation of lysosome membrane permeability http://purl.obolibrary.org/obo/GO_0097213 GO:0097212 biolink:BiologicalProcess lysosomal membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. go-plus.json lysosome membrane organization|lysosomal membrane organisation http://purl.obolibrary.org/obo/GO_0097212 GO:0000303 biolink:BiologicalProcess response to superoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. go-plus.json http://purl.obolibrary.org/obo/GO_0000303 GO:0000302 biolink:BiologicalProcess response to reactive oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. go-plus.json response to AOS|response to reactive oxidative species|response to reactive oxygen intermediate|response to ROS|response to active oxygen species|response to ROI http://purl.obolibrary.org/obo/GO_0000302 GO:0000301 biolink:BiologicalProcess retrograde transport, vesicle recycling within Golgi The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi. go-plus.json retrograde (vesicle recycling within Golgi) transport http://purl.obolibrary.org/obo/GO_0000301 GO:0000300 biolink:CellularComponent obsolete peripheral to membrane of membrane fraction OBSOLETE. Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH. go-plus.json peripheral to membrane of membrane fraction http://purl.obolibrary.org/obo/GO_0000300 GO:1903489 biolink:BiologicalProcess positive regulation of lactation Any process that activates or increases the frequency, rate or extent of lactation. go-plus.json upregulation of lactation|up regulation of lactation|activation of lactation|up-regulation of lactation http://purl.obolibrary.org/obo/GO_1903489 GO:1903488 biolink:BiologicalProcess negative regulation of lactation Any process that stops, prevents or reduces the frequency, rate or extent of lactation. go-plus.json down regulation of lactation|downregulation of lactation|down-regulation of lactation|inhibition of lactation http://purl.obolibrary.org/obo/GO_1903488 GO:1903487 biolink:BiologicalProcess regulation of lactation Any process that modulates the frequency, rate or extent of lactation. go-plus.json http://purl.obolibrary.org/obo/GO_1903487 GO:1903486 biolink:BiologicalProcess establishment of mitotic actomyosin contractile ring localization Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle. go-plus.json establishment of actomyosin contractile ring localization involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903486 GO:1903496 biolink:BiologicalProcess response to 11-deoxycorticosterone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903496 GO:1903495 biolink:BiologicalProcess cellular response to dehydroepiandrosterone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903495 GO:1903494 biolink:BiologicalProcess response to dehydroepiandrosterone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903494 CHEBI:38226 biolink:ChemicalSubstance 1,2-dithiolane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38226 chebi_ph7_3 GO:1903493 biolink:BiologicalProcess response to clopidogrel Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. go-plus.json http://purl.obolibrary.org/obo/GO_1903493 GO:1903492 biolink:BiologicalProcess response to acetylsalicylate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903492 GO:1903491 biolink:BiologicalProcess response to simvastatin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug. go-plus.json http://purl.obolibrary.org/obo/GO_1903491 gocheck_do_not_manually_annotate GO:1903490 biolink:BiologicalProcess positive regulation of mitotic cytokinesis Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis. go-plus.json upregulation of cytokinesis after mitosis|up-regulation of mitotic cytokinesis|up regulation of cytokinesis after mitosis|upregulation of mitotic cytokinesis|positive regulation of cytokinesis after mitosis|activation of cytokinesis after mitosis|up regulation of mitotic cytokinesis|up-regulation of cytokinesis after mitosis|activation of mitotic cytokinesis http://purl.obolibrary.org/obo/GO_1903490 CHEBI:38229 biolink:ChemicalSubstance solanapyrone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_38229 chebi_ph7_3 GO:0000307 biolink:CellularComponent cyclin-dependent protein kinase holoenzyme complex Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner. go-plus.json CDK holoenzyme http://purl.obolibrary.org/obo/GO_0000307 goslim_pir GO:0097219 biolink:CellularComponent compound sieve plate A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement. go-plus.json http://purl.obolibrary.org/obo/GO_0097219 GO:0000306 biolink:CellularComponent extrinsic component of vacuolar membrane The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to vacuolar membrane http://purl.obolibrary.org/obo/GO_0000306 GO:0097218 biolink:CellularComponent sieve plate A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas. go-plus.json http://purl.obolibrary.org/obo/GO_0097218 GO:0000305 biolink:BiologicalProcess response to oxygen radical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. go-plus.json http://purl.obolibrary.org/obo/GO_0000305 GO:0000304 biolink:BiologicalProcess response to singlet oxygen Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst. go-plus.json http://purl.obolibrary.org/obo/GO_0000304 GO:0097215 biolink:BiologicalProcess negative regulation of lysosomal membrane permeability Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane. go-plus.json negative regulation of lysosome membrane permeability http://purl.obolibrary.org/obo/GO_0097215 CHEBI:38224 biolink:ChemicalSubstance fumonisin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38224 GO:0097214 biolink:BiologicalProcess positive regulation of lysosomal membrane permeability Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane. go-plus.json positive regulation of lysosome membrane permeability http://purl.obolibrary.org/obo/GO_0097214 GO:0000309 biolink:MolecularActivity nicotinamide-nucleotide adenylyltransferase activity Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. RHEA:21360|MetaCyc:2.7.7.1-RXN|Reactome:R-HSA-8939959|EC:2.7.7.1 go-plus.json ATP:nicotinamide-nucleotide adenylyltransferase activity|NAD(+) pyrophosphorylase activity|nicotinamide adenine dinucleotide pyrophosphorylase activity|NAD(+) diphosphorylase activity|adenosine triphosphate-nicotinamide mononucleotide transadenylase activity|nicotinamide mononucleotide adenylyltransferase activity|NMNAT activity|NMN adenylyltransferase activity|NAD+ pyrophosphorylase activity|NAD+ diphosphorylase activity|diphosphopyridine nucleotide pyrophosphorylase activity|ATP:NMN adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0000309 GO:0097217 biolink:CellularComponent sieve area A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements. go-plus.json http://purl.obolibrary.org/obo/GO_0097217 CHEBI:38222 biolink:ChemicalSubstance hydrocarbyl anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38222 GO:0000308 biolink:CellularComponent cytoplasmic cyclin-dependent protein kinase holoenzyme complex Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm. go-plus.json CDK holoenzyme http://purl.obolibrary.org/obo/GO_0000308 GO:0097216 biolink:MolecularActivity guanosine tetraphosphate binding Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions. go-plus.json 5'-ppGpp-3' binding http://purl.obolibrary.org/obo/GO_0097216 CHEBI:38221 biolink:ChemicalSubstance fumonisin B1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_38221 GO:0000310 biolink:MolecularActivity xanthine phosphoribosyltransferase activity Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate. RHEA:10800|EC:2.4.2.22|MetaCyc:XANPRIBOSYLTRAN-RXN go-plus.json XMP pyrophosphorylase activity|xanthine-guanine phosphoribosyltransferase activity|xanthosine 5'-phosphate pyrophosphorylase activity|Xan phosphoribosyltransferase activity|5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity|xanthylic pyrophosphorylase activity|xanthylate pyrophosphorylase activity|XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0000310 GO:0097222 biolink:BiologicalProcess mitochondrial mRNA polyadenylation The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails. go-plus.json http://purl.obolibrary.org/obo/GO_0097222 GO:0097221 biolink:CellularComponent M/G1 phase-specific MADS box-forkhead transcription factor complex A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2. go-plus.json pombe cell cycle box binding factor complex|PCB binding factor complex|PBF transcription complex|PBF complex http://purl.obolibrary.org/obo/GO_0097221 GO:0097224 biolink:CellularComponent sperm connecting piece The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum. go-plus.json http://purl.obolibrary.org/obo/GO_0097224 GO:0097223 biolink:CellularComponent obsolete sperm part OBSOLETE. Any constituent part of a sperm, a mature male germ cell that develops from a spermatid. go-plus.json http://purl.obolibrary.org/obo/GO_0097223 gocheck_do_not_annotate GO:0000314 biolink:CellularComponent organellar small ribosomal subunit The smaller of the two subunits of an organellar ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000314 GO:0000313 biolink:CellularComponent organellar ribosome A ribosome contained within a subcellular membrane-bounded organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0000313 GO:0097220 biolink:CellularComponent simple sieve plate A sieve plate that contains a single specialized sieve area. go-plus.json http://purl.obolibrary.org/obo/GO_0097220 GO:0000312 biolink:CellularComponent plastid small ribosomal subunit The smaller of the two subunits of a plastid ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000312 GO:0000311 biolink:CellularComponent plastid large ribosomal subunit The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). go-plus.json http://purl.obolibrary.org/obo/GO_0000311 GO:1903499 biolink:BiologicalProcess regulation of mitotic actomyosin contractile ring assembly Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly. go-plus.json regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|regulation of contractile ring assembly involved in mitotic cytokinesis|regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|regulation of mitotic cytokinesis, actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_1903499 GO:1903498 biolink:BiologicalProcess bundle sheath cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell. go-plus.json http://purl.obolibrary.org/obo/GO_1903498 GO:1903497 biolink:BiologicalProcess cellular response to 11-deoxycorticosterone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903497 CHEBI:38238 biolink:ChemicalSubstance prosolanapyrone II go-plus.json http://purl.obolibrary.org/obo/CHEBI_38238 chebi_ph7_3 CHEBI:38237 biolink:ChemicalSubstance prosolanapyrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38237 GO:0000318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000318 CHEBI:38231 biolink:ChemicalSubstance phytotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38231 CHEBI:38230 biolink:ChemicalSubstance solanapyrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38230 GO:0000317 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000317 GO:0097229 biolink:CellularComponent sperm end piece The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0097229 GO:0000316 biolink:BiologicalProcess sulfite transport The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sulphite transport http://purl.obolibrary.org/obo/GO_0000316 GO:0000315 biolink:CellularComponent organellar large ribosomal subunit The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). go-plus.json http://purl.obolibrary.org/obo/GO_0000315 GO:0097226 biolink:CellularComponent sperm mitochondrial sheath The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum. go-plus.json http://purl.obolibrary.org/obo/GO_0097226 GO:0097225 biolink:CellularComponent sperm midpiece The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece. go-plus.json http://purl.obolibrary.org/obo/GO_0097225 CHEBI:38234 biolink:ChemicalSubstance DNA polymerase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38234 GO:0097228 biolink:CellularComponent sperm principal piece The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece. go-plus.json http://purl.obolibrary.org/obo/GO_0097228 GO:0097227 biolink:CellularComponent sperm annulus The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity. go-plus.json http://purl.obolibrary.org/obo/GO_0097227 GO:0000319 biolink:MolecularActivity sulfite transmembrane transporter activity Enables the transfer of sulfite ions from one side of a membrane to the other. go-plus.json sulphite transporter activity http://purl.obolibrary.org/obo/GO_0000319 GO:0097277 biolink:BiologicalProcess cellular urea homeostasis Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097277 GO:0097276 biolink:BiologicalProcess cellular creatinine homeostasis Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097276 GO:0097279 biolink:BiologicalProcess histamine secretion mediated by IgE immunoglobulin Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen. go-plus.json Ig-mediated histamine release|histamine secretion mediated by IgE antibody http://purl.obolibrary.org/obo/GO_0097279 GO:0097278 biolink:BiologicalProcess complement-dependent cytotoxicity Cell killing caused by the membrane attack complex formed following complement activation. go-plus.json http://purl.obolibrary.org/obo/GO_0097278 CHEBI:28887 biolink:ChemicalSubstance dimethyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_28887 chebi_ph7_3 GO:0097273 biolink:BiologicalProcess creatinine homeostasis Any biological process involved in the maintenance of an internal steady state of creatinine. go-plus.json http://purl.obolibrary.org/obo/GO_0097273 GO:0097272 biolink:BiologicalProcess ammonium homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium. go-plus.json ammonia homeostasis http://purl.obolibrary.org/obo/GO_0097272 GO:0097275 biolink:BiologicalProcess cellular ammonium homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium at the level of the cell. go-plus.json cellular ammonia homeostasis http://purl.obolibrary.org/obo/GO_0097275 CHEBI:28889 biolink:ChemicalSubstance 5,6,7,8-tetrahydropteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28889 chebi_ph7_3 GO:0097274 biolink:BiologicalProcess urea homeostasis Any biological process involved in the maintenance of an internal steady state of urea. go-plus.json http://purl.obolibrary.org/obo/GO_0097274 GO:0097271 biolink:BiologicalProcess protein localization to bud neck A process in which a protein is transported to, or maintained at, a location within a cellular bud neck. go-plus.json protein localization to cellular bud neck|protein localisation to bud neck http://purl.obolibrary.org/obo/GO_0097271 CHEBI:28885 biolink:ChemicalSubstance butan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28885 chebi_ph7_3 GO:0097270 biolink:BiologicalProcess dishabituation The temporary recovery of response to a stimulus when a novel stimulus is added. go-plus.json http://purl.obolibrary.org/obo/GO_0097270 CHEBI:28884 biolink:ChemicalSubstance N-phenylacetamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28884 chebi_ph7_3 CHEBI:28881 biolink:ChemicalSubstance 2-acetamido-3-O-[(1R)-1-carboxylatoethyl]-2-deoxy-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28881 chebi_ph7_3 CHEBI:28880 biolink:ChemicalSubstance (S)-mevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28880 CHEBI:38206 biolink:ChemicalSubstance chlorophyllide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38206 CHEBI:38209 biolink:ChemicalSubstance chlorophyllide b go-plus.json http://purl.obolibrary.org/obo/CHEBI_38209 CHEBI:38208 biolink:ChemicalSubstance aminoacylpyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38208 CHEBI:38201 biolink:ChemicalSubstance bacteriochlorophyll go-plus.json http://purl.obolibrary.org/obo/CHEBI_38201 chebi_ph7_3 GO:0097288 biolink:BiologicalProcess 7-cyano-7-deazaguanine biosynthetic process The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo. go-plus.json 7-cyano-7-deazaguanine anabolism|7-cyano-7-deazaguanine biosynthesis|7-cyano-7-deazaguanine synthesis|7-cyano-7-deazaguanine formation http://purl.obolibrary.org/obo/GO_0097288 GO:0097287 biolink:BiologicalProcess 7-cyano-7-deazaguanine metabolic process The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo. go-plus.json 7-cyano-7-deazaguanine metabolism http://purl.obolibrary.org/obo/GO_0097287 GO:0097289 biolink:BiologicalProcess alpha-ribazole metabolic process The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12). go-plus.json alpha-ribazole metabolism http://purl.obolibrary.org/obo/GO_0097289 GO:0097284 biolink:BiologicalProcess hepatocyte apoptotic process Any apoptotic process in a hepatocyte, the main structural component of the liver. go-plus.json hepatocyte apoptosis http://purl.obolibrary.org/obo/GO_0097284 CHEBI:28898 biolink:ChemicalSubstance P(1),P(5)-bis(5'-adenosyl) pentaphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28898 GO:0097283 biolink:BiologicalProcess keratinocyte apoptotic process Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. go-plus.json keratinocyte apoptosis http://purl.obolibrary.org/obo/GO_0097283 CHEBI:28897 biolink:ChemicalSubstance pentadecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28897 chebi_ph7_3 GO:0097286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097286 GO:0097285 biolink:BiologicalProcess obsolete cell-type specific apoptotic process OBSOLETE. Any apoptotic process in a specific cell type. go-plus.json cell-type specific apoptosis http://purl.obolibrary.org/obo/GO_0097285 GO:0097280 biolink:BiologicalProcess histamine secretion mediated by immunoglobulin Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface. go-plus.json http://purl.obolibrary.org/obo/GO_0097280 CHEBI:28894 biolink:ChemicalSubstance 1-O-alkyl-2-O-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28894 chebi_ph7_3 GO:0097282 biolink:BiologicalProcess immunoglobulin-mediated neutralization The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin. go-plus.json antibody-mediated neutralization http://purl.obolibrary.org/obo/GO_0097282 GO:0097281 biolink:BiologicalProcess immune complex formation The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus. go-plus.json antibody-mediated agglutination http://purl.obolibrary.org/obo/GO_0097281 CHEBI:28895 biolink:ChemicalSubstance 3'-UMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28895 CHEBI:28890 biolink:ChemicalSubstance coenzyme B go-plus.json http://purl.obolibrary.org/obo/CHEBI_28890 CHEBI:28892 biolink:ChemicalSubstance ganglioside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28892 CHEBI:28891 biolink:ChemicalSubstance oxanthrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28891 chebi_ph7_3 CHEBI:38215 biolink:ChemicalSubstance calcium channel blocker go-plus.json http://purl.obolibrary.org/obo/CHEBI_38215 GO:0097255 biolink:CellularComponent R2TP complex A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others. go-plus.json http://purl.obolibrary.org/obo/GO_0097255 CHEBI:28869 biolink:ChemicalSubstance menadione go-plus.json http://purl.obolibrary.org/obo/CHEBI_28869 chebi_ph7_3 GO:0097254 biolink:BiologicalProcess renal tubular secretion Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs. go-plus.json http://purl.obolibrary.org/obo/GO_0097254 CHEBI:28868 biolink:ChemicalSubstance fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_28868 chebi_ph7_3 GO:0097257 biolink:MolecularActivity leukotriene B4 12-hydroxy dehydrogenase activity Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+). Reactome:R-HSA-2161567|RHEA:50608 go-plus.json leukotriene B4 12-hydroxydehydrogenase activity http://purl.obolibrary.org/obo/GO_0097257 GO:0097256 biolink:MolecularActivity phenyllactate dehydrogenase activity Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH. RHEA:38351|EC:1.1.1.110 go-plus.json http://purl.obolibrary.org/obo/GO_0097256 GO:0014909 biolink:BiologicalProcess smooth muscle cell migration The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/GO_0014909 GO:0097251 biolink:BiologicalProcess leukotriene B4 biosynthetic process The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. go-plus.json leukotriene B4 biosynthesis|LTB4 formation|leukotriene B4 anabolism|leukotriene B4 synthesis|LTB4 anabolism|leukotriene B4 formation|LTB4 biosynthesis|LTB4 synthesis http://purl.obolibrary.org/obo/GO_0097251 CHEBI:28865 biolink:ChemicalSubstance taurocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28865 GO:0097250 biolink:BiologicalProcess mitochondrial respirasome assembly The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex. go-plus.json mitochondrial respiratory chain supercomplex assembly|mitochondrial respiratory supercomplex assembly http://purl.obolibrary.org/obo/GO_0097250 CHEBI:28864 biolink:ChemicalSubstance tobramycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28864 CHEBI:28867 biolink:ChemicalSubstance O-propanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28867 chebi_ph7_3 GO:0097253 biolink:MolecularActivity beta-hydroxybutyrate transmembrane transporter activity Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid. go-plus.json (R)-3-hydroxybutyrate transmembrane transporter activity|3-hydroxybutanoic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0097253 GO:0097252 biolink:BiologicalProcess oligodendrocyte apoptotic process Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons. go-plus.json oligodendrocyte apoptosis http://purl.obolibrary.org/obo/GO_0097252 CHEBI:28866 biolink:ChemicalSubstance tetracosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28866 GO:0014904 biolink:BiologicalProcess myotube cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014904 CHEBI:28861 biolink:ChemicalSubstance gibberellin A8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28861 CHEBI:28860 biolink:ChemicalSubstance beta-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28860 GO:0014902 biolink:BiologicalProcess myotube differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014902 CHEBI:28863 biolink:ChemicalSubstance flavanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_28863 chebi_ph7_3 GO:0014901 biolink:BiologicalProcess satellite cell activation involved in skeletal muscle regeneration The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. go-plus.json http://purl.obolibrary.org/obo/GO_0014901 CHEBI:28862 biolink:ChemicalSubstance dGDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28862 GO:0014908 biolink:BiologicalProcess myotube differentiation involved in skeletal muscle regeneration The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014908 GO:0014906 biolink:BiologicalProcess myotube cell development involved in skeletal muscle regeneration The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014906 GO:0014905 biolink:BiologicalProcess myoblast fusion involved in skeletal muscle regeneration A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014905 GO:0014900 biolink:BiologicalProcess muscle hyperplasia A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ. go-plus.json http://purl.obolibrary.org/obo/GO_0014900 GO:0097259 biolink:MolecularActivity 20-aldehyde-leukotriene B4 20-monooxygenase activity Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase]. RHEA:48672|Reactome:R-HSA-2161792|Reactome:R-HSA-2161979 go-plus.json http://purl.obolibrary.org/obo/GO_0097259 GO:0097258 biolink:MolecularActivity 20-hydroxy-leukotriene B4 omega oxidase activity Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized [NADPH-hemoprotein reductase]. RHEA:48668|Reactome:R-HSA-2161745 go-plus.json 20-hydroxy-leukotriene B4 omega-oxidation|20-hydroxy-leukotriene B4 omega-oxidase activity http://purl.obolibrary.org/obo/GO_0097258 GO:0097266 biolink:MolecularActivity phenylacetyl-CoA 1,2-epoxidase activity Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+). KEGG_REACTION:R09838|RHEA:32171|EC:1.14.13.149 go-plus.json phenylacetyl-CoA epoxidase activity|ring 1,2-phenylacetyl-CoA epoxidase activity|phenylacetyl-CoA monooxygenase activity http://purl.obolibrary.org/obo/GO_0097266 GO:0097265 biolink:MolecularActivity 5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+). Reactome:R-HSA-2161776 go-plus.json 5-HETE dehydrogenase activity|5(S)-HETE dehydrogenase activity|5-hydroxy-eicosatetraenoic acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0097265 CHEBI:28879 biolink:ChemicalSubstance 9-O-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28879 GO:0097268 biolink:CellularComponent cytoophidium A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human. go-plus.json http://purl.obolibrary.org/obo/GO_0097268 GO:0097267 biolink:BiologicalProcess omega-hydroxylase P450 pathway The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation. go-plus.json P450 omega-hydroxylase pathway http://purl.obolibrary.org/obo/GO_0097267 GO:0097262 biolink:MolecularActivity eoxin D4 synthase activity Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid. Reactome:R-HSA-2161945 go-plus.json http://purl.obolibrary.org/obo/GO_0097262 GO:0097261 biolink:MolecularActivity eoxin C4 synthase activity Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4. Reactome:R-HSA-2161768 go-plus.json http://purl.obolibrary.org/obo/GO_0097261 CHEBI:28875 biolink:ChemicalSubstance tetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28875 CHEBI:28878 biolink:ChemicalSubstance dodecan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28878 chebi_ph7_3 GO:0097264 biolink:BiologicalProcess self proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. go-plus.json autolysis|self-proteolysis http://purl.obolibrary.org/obo/GO_0097264 GO:0097263 biolink:MolecularActivity eoxin E4 synthase activity Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine. Reactome:R-HSA-2161868 go-plus.json http://purl.obolibrary.org/obo/GO_0097263 GO:0014915 biolink:BiologicalProcess regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014915 GO:0014914 biolink:BiologicalProcess myoblast maturation involved in muscle regeneration A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014914 GO:0097260 biolink:MolecularActivity eoxin A4 synthase activity Catalysis of the reaction: leukotriene A4 = eoxin A4. Reactome:R-HSA-2162019 go-plus.json http://purl.obolibrary.org/obo/GO_0097260 CHEBI:28874 biolink:ChemicalSubstance phosphatidylinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28874 GO:0014912 biolink:BiologicalProcess negative regulation of smooth muscle cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0014912 CHEBI:28873 biolink:ChemicalSubstance cis-2-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28873 GO:0014918 biolink:BiologicalProcess obsolete positive regulation of natriuresis by pressure natriuresis OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis. go-plus.json positive regulation of natriuresis by pressure natriuresis http://purl.obolibrary.org/obo/GO_0014918 GO:0014917 biolink:BiologicalProcess obsolete positive regulation of diuresis by pressure natriuresis OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis. go-plus.json positive regulation of diuresis by pressure natriuresis http://purl.obolibrary.org/obo/GO_0014917 CHEBI:28870 biolink:ChemicalSubstance 1-O-all-trans-retinoyl-beta-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28870 GO:0014916 biolink:BiologicalProcess regulation of lung blood pressure The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure. go-plus.json regulation of pulmonary blood pressure http://purl.obolibrary.org/obo/GO_0014916 GO:0014911 biolink:BiologicalProcess positive regulation of smooth muscle cell migration Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0014911 GO:0014910 biolink:BiologicalProcess regulation of smooth muscle cell migration Any process that modulates the frequency, rate or extent of smooth muscle cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0014910 GO:0097269 biolink:MolecularActivity all-trans-decaprenyl-diphosphate synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate. Reactome:R-HSA-2162253|RHEA:27802|EC:2.5.1.91 go-plus.json (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|2-trans,6-trans-farnesyl diphosphate activity http://purl.obolibrary.org/obo/GO_0097269 GO:0000288 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. go-plus.json nuclear mRNA catabolic process, deadenylation-dependent decay|mRNA catabolic process, deadenylation-dependent|mRNA catabolism, deadenylation-dependent|mRNA breakdown, deadenylation-dependent decay|mRNA degradation, deadenylation-dependent decay|mRNA catabolic process, deadenylylation-dependent|deadenylation-dependent mRNA decay|mRNA catabolism, deadenylylation-dependent http://purl.obolibrary.org/obo/GO_0000288 GO:0048222 biolink:CellularComponent glycoprotein network An extracellular matrix part that consists of cross-linked glycoproteins. Wikipedia:Extensin go-plus.json extensin http://purl.obolibrary.org/obo/GO_0048222 GO:0000287 biolink:MolecularActivity magnesium ion binding Binding to a magnesium (Mg) ion. go-plus.json Mg binding|magnesium binding http://purl.obolibrary.org/obo/GO_0000287 GO:0048221 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048221 GO:0000286 biolink:MolecularActivity alanine dehydrogenase activity Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+). EC:1.4.1.1|MetaCyc:ALANINE-DEHYDROGENASE-RXN|RHEA:18405 go-plus.json L-alanine dehydrogenase activity|NAD-dependent alanine dehydrogenase activity|NADH-dependent alanine dehydrogenase activity|alanine oxidoreductase activity|alpha-alanine dehydrogenase activity|NAD-linked alanine dehydrogenase activity|AlaDH|L-alanine:NAD+ oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0000286 GO:0048220 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048220 GO:0000285 biolink:MolecularActivity 1-phosphatidylinositol-3-phosphate 5-kinase activity Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+). Reactome:R-HSA-1676168|EC:2.7.1.150|Reactome:R-HSA-1675921|Reactome:R-HSA-1676134|Reactome:R-HSA-1675910|RHEA:13609|KEGG_REACTION:R05802|MetaCyc:2.7.1.150-RXN go-plus.json type III PIP kinase activity|phosphatidylinositol-3-phosphate 5-kinase activity|phosphatidylinositol 3-phosphate 5-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0000285 CHEBI:63171 biolink:ChemicalSubstance mononitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63171 CHEBI:87141 biolink:ChemicalSubstance 3-oxocholesta-4,24-dien-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87141 GO:0000289 biolink:BiologicalProcess nuclear-transcribed mRNA poly(A) tail shortening Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. go-plus.json nuclear mRNA poly(A) tail shortening|3' to 5' mRNA deadenylation|mRNA deadenylation http://purl.obolibrary.org/obo/GO_0000289 GO:0000280 biolink:BiologicalProcess nuclear division The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. go-plus.json karyokinesis http://purl.obolibrary.org/obo/GO_0000280 goslim_pir GO:0048229 biolink:BiologicalProcess gametophyte development The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana. go-plus.json gametogenesis http://purl.obolibrary.org/obo/GO_0048229 CHEBI:87142 biolink:ChemicalSubstance N-myristoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87142 GO:0048228 biolink:BiologicalProcess obsolete actin cortical patch distribution OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells. go-plus.json actin cortical patch distribution http://purl.obolibrary.org/obo/GO_0048228 GO:0048227 biolink:BiologicalProcess plasma membrane to endosome transport Transport of a vesicle from the plasma membrane to the endosome. go-plus.json http://purl.obolibrary.org/obo/GO_0048227 CHEBI:63173 biolink:ChemicalSubstance T-cell proliferation inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63173 GO:0000284 biolink:BiologicalProcess obsolete shmoo orientation OBSOLETE. (Was not defined before being made obsolete). go-plus.json shmoo orientation http://purl.obolibrary.org/obo/GO_0000284 GO:0048226 biolink:CellularComponent Casparian strip Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants. Wikipedia:Casparian_strip go-plus.json http://purl.obolibrary.org/obo/GO_0048226 GO:0048225 biolink:CellularComponent suberin network An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0048225 GO:0000283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000283 GO:0000282 biolink:BiologicalProcess cellular bud site selection The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae. go-plus.json bud site selection/establishment of cell polarity http://purl.obolibrary.org/obo/GO_0000282 GO:0048224 biolink:CellularComponent lignin network An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0048224 CHEBI:63178 biolink:ChemicalSubstance (13R)-edaxadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63178 chebi_ph7_3 GO:0000281 biolink:BiologicalProcess mitotic cytokinesis A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. go-plus.json cytokinesis after mitosis http://purl.obolibrary.org/obo/GO_0000281 goslim_pombe GO:0048223 biolink:CellularComponent hemicellulose network Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan. go-plus.json http://purl.obolibrary.org/obo/GO_0048223 CHEBI:63177 biolink:ChemicalSubstance 11alpha-hydroxy-beta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63177 chebi_ph7_3 CHEBI:133574 biolink:ChemicalSubstance 5-hydroxylysinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_133574 chebi_ph7_3 CHEBI:133575 biolink:ChemicalSubstance N-acyl-gamma-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133575 chebi_ph7_3 CHEBI:133577 biolink:ChemicalSubstance 2-hydroxy-4-methylvalerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133577 chebi_ph7_3 GO:0048233 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048233 GO:0000299 biolink:CellularComponent obsolete integral to membrane of membrane fraction OBSOLETE. Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes. go-plus.json integral to membrane of membrane fraction http://purl.obolibrary.org/obo/GO_0000299 GO:0048232 biolink:BiologicalProcess male gamete generation Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0048232 GO:0000298 biolink:MolecularActivity endopolyphosphatase activity Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. EC:3.6.1.10|RHEA:22452|MetaCyc:ENDOPOLYPHOSPHATASE-RXN go-plus.json polyphosphatase activity|metaphosphatase activity|polyphosphate polyphosphohydrolase activity|polyphosphate depolymerase activity|polymetaphosphatase activity http://purl.obolibrary.org/obo/GO_0000298 GO:0048231 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048231 GO:0000297 biolink:MolecularActivity spermine transmembrane transporter activity Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0000297 GO:0000296 biolink:BiologicalProcess spermine transport The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0000296 GO:0048230 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048230 CHEBI:63180 biolink:ChemicalSubstance (13S)-edaxadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63180 chebi_ph7_3 GO:0000291 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, exonucleolytic The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail. go-plus.json nuclear mRNA catabolic process, exonucleolytic|mRNA degradation, exonucleolytic|mRNA breakdown, exonucleolytic|exonucleolytic degradation of mRNA http://purl.obolibrary.org/obo/GO_0000291 GO:0000290 biolink:BiologicalProcess deadenylation-dependent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length. go-plus.json deadenylation-dependent decapping of nuclear mRNA|deadenylylation-dependent decapping http://purl.obolibrary.org/obo/GO_0000290 CHEBI:87131 biolink:ChemicalSubstance O-(S-L-2-amino-6-adipoylpantetheine-4'-phosphoryl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87131 chebi_ph7_3 GO:0048239 biolink:BiologicalProcess negative regulation of DNA recombination at telomere Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere. go-plus.json downregulation of telomeric recombination at telomere|negative regulation of telomeric recombination at telomere|suppression of telomeric recombination at telomere|down-regulation of telomeric recombination at telomere|inhibition of telomeric recombination at telomere|down regulation of telomeric recombination at telomere http://purl.obolibrary.org/obo/GO_0048239 CHEBI:63184 biolink:ChemicalSubstance 11-oxo-beta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63184 chebi_ph7_3 GO:0048238 biolink:CellularComponent smooth endoplasmic reticulum lumen The volume enclosed by the membranes of the smooth endoplasmic reticulum. NIF_Subcellular:sao927884761 go-plus.json SER lumen|smooth ER lumen http://purl.obolibrary.org/obo/GO_0048238 CHEBI:87133 biolink:ChemicalSubstance 7-methyl-GTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87133 chebi_ph7_3 GO:0048237 biolink:CellularComponent rough endoplasmic reticulum lumen The volume enclosed by the membranes of the rough endoplasmic reticulum. NIF_Subcellular:sao1819509473 go-plus.json RER lumen|rough ER lumen http://purl.obolibrary.org/obo/GO_0048237 CHEBI:87136 biolink:ChemicalSubstance trans-caffeoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87136 chebi_ph7_3 GO:0000295 biolink:MolecularActivity adenine nucleotide transmembrane transporter activity Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other. Reactome:R-HSA-389652 go-plus.json http://purl.obolibrary.org/obo/GO_0000295 GO:0000294 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends. go-plus.json nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay|mRNA catabolic process, endonucleolytic|mRNA catabolism, endonucleolytic|endonucleolytic mRNA decay|mRNA degradation, endonucleolytic cleavage-dependent decay|mRNA breakdown, endonucleolytic cleavage-dependent decay http://purl.obolibrary.org/obo/GO_0000294 GO:0048236 biolink:BiologicalProcess plant-type sporogenesis The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes. go-plus.json plant spore formation http://purl.obolibrary.org/obo/GO_0048236 GO:0048235 biolink:BiologicalProcess pollen sperm cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte. go-plus.json male gametophyte sperm cell differentiation|sperm cell differentiation|male gamete generation http://purl.obolibrary.org/obo/GO_0048235 GO:0000293 biolink:MolecularActivity ferric-chelate reductase activity Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe3+-siderophore + electron acceptor. go-plus.json iron chelate reductase activity|ferric chelate reductase activity http://purl.obolibrary.org/obo/GO_0000293 GO:0000292 biolink:BiologicalProcess RNA fragment catabolic process The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. go-plus.json RNA fragment breakdown|RNA fragment catabolism|group I intron catabolic process|RNA fragment degradation http://purl.obolibrary.org/obo/GO_0000292 GO:0048234 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048234 CHEBI:87137 biolink:ChemicalSubstance dihydrocaffeoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87137 chebi_ph7_3 CHEBI:133585 biolink:ChemicalSubstance epoxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133585 chebi_ph7_3 CHEBI:87139 biolink:ChemicalSubstance 3-oxochol-4-en-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87139 CHEBI:133586 biolink:ChemicalSubstance epoxyoctadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133586 GO:0000266 biolink:BiologicalProcess mitochondrial fission The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. go-plus.json mitochondrial division|mitochondrial proliferation http://purl.obolibrary.org/obo/GO_0000266 GO:0048244 biolink:MolecularActivity phytanoyl-CoA dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate. MetaCyc:1.14.11.18-RXN|KEGG_REACTION:R05722|Reactome:R-HSA-389639|EC:1.14.11.18|RHEA:16065 go-plus.json phytanoyl-CoA hydroxylase activity|phytanoyl-CoA 2-hydroxylase activity|phytanoyl-CoA 2 oxoglutarate dioxygenase activity|phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)|phytanoyl-CoA alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0048244 CHEBI:63190 biolink:ChemicalSubstance (+)-beta-caryophyllene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63190 chebi_ph7_3 GO:0048243 biolink:BiologicalProcess norepinephrine secretion The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. go-plus.json noradrenaline secretion http://purl.obolibrary.org/obo/GO_0048243 GO:0000265 biolink:MolecularActivity obsolete heterotrimeric G-protein GTPase, gamma-subunit OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit. go-plus.json heterotrimeric G-protein GTPase, gamma-subunit http://purl.obolibrary.org/obo/GO_0000265 GO:0000264 biolink:MolecularActivity obsolete heterotrimeric G-protein GTPase, beta-subunit OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit. go-plus.json heterotrimeric G-protein GTPase, beta-subunit http://purl.obolibrary.org/obo/GO_0000264 GO:0048242 biolink:BiologicalProcess epinephrine secretion The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system. go-plus.json adrenaline secretion http://purl.obolibrary.org/obo/GO_0048242 GO:0000263 biolink:MolecularActivity obsolete heterotrimeric G-protein GTPase, alpha-subunit OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity. go-plus.json heterotrimeric G-protein GTPase, alpha-subunit http://purl.obolibrary.org/obo/GO_0000263 GO:0048241 biolink:BiologicalProcess epinephrine transport The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json adrenaline transport http://purl.obolibrary.org/obo/GO_0048241 GO:1903409 biolink:BiologicalProcess reactive oxygen species biosynthetic process The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. go-plus.json ROS generation|reactive oxygen species biosynthesis|reactive oxygen species generation|reactive oxygen species anabolism|reactive oxygen species synthesis|reactive oxygen species formation|ROS formation http://purl.obolibrary.org/obo/GO_1903409 GO:0048240 biolink:BiologicalProcess sperm capacitation A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. go-plus.json sperm activation http://purl.obolibrary.org/obo/GO_0048240 CHEBI:87161 biolink:ChemicalSubstance dihydrobisanhydrobacterioruberin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87161 chebi_ph7_3 CHEBI:63194 biolink:ChemicalSubstance D-ravidosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63194 CHEBI:38194 biolink:ChemicalSubstance 5alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38194 GO:1903408 biolink:BiologicalProcess positive regulation of P-type sodium:potassium-exchanging transporter activity Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity. go-plus.json upregulation of Na,K-pump|activation of Na+,K+ pump|up regulation of sodium/potassium-exchanging ATPase activity|upregulation of (Na+ + K+)-activated ATPase activity|upregulation of Na+,K+-ATPase activity|positive regulation of sodium/potassium-exchanging ATPase activity|up-regulation of sodium:potassium-exchanging ATPase activity|activation of sodium/potassium-exchanging ATPase activity|up regulation of sodium:potassium exchanging ATPase activity|activation of sodium:potassium exchanging ATPase activity|positive regulation of sodium:potassium exchanging ATPase activity|up-regulation of Na(+)/K(+)-exchanging ATPase activity|positive regulation of (Na+ + K+)-ATPase activity|up-regulation of Na+,K+ pump|up-regulation of Na+/K+-exchanging ATPase activity|positive regulation of Na,K-activated ATPase activity|upregulation of ATP phosphohydrolase (Na+/K+-exchanging)|up-regulation of Na+/K+-ATPase activity|up regulation of sodium/potassium-transporting ATPase activity|up-regulation of Na(+)/K(+)-ATPase activity|up regulation of (Na+ + K+)-ATPase activity|up regulation of Na,K-activated ATPase activity|positive regulation of sodium:potassium-exchanging ATPase activity|activation of Na(+)/K(+)-ATPase activity|activation of Na+/K+-ATPase activity|up-regulation of (Na+ + K+)-activated ATPase activity|up regulation of Na,K-pump|activation of sodium/potassium-transporting ATPase activity|positive regulation of sodium/potassium-transporting ATPase activity|up-regulation of Na+,K+-ATPase activity|activation of (Na+ + K+)-activated ATPase activity|positive regulation of Na,K-pump|activation of Na+,K+-ATPase activity|upregulation of sodium:potassium-exchanging ATPase activity|up-regulation of sodium/potassium-exchanging ATPase activity|upregulation of Na+/K+-exchanging ATPase activity|upregulation of Na+,K+ pump|upregulation of Na(+)/K(+)-exchanging ATPase activity|up-regulation of sodium:potassium exchanging ATPase activity|up-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|activation of Na,K-pump|upregulation of (Na+ + K+)-ATPase activity|activation of ATP phosphohydrolase (Na+/K+-exchanging)|positive regulation of Na+/K+-ATPase activity|upregulation of Na,K-activated ATPase activity|positive regulation of Na(+)/K(+)-ATPase activity|positive regulation of (Na+ + K+)-activated ATPase activity|up regulation of Na+/K+-ATPase activity|up-regulation of sodium/potassium-transporting ATPase activity|up regulation of Na(+)/K(+)-ATPase activity|positive regulation of Na+,K+-ATPase activity|up regulation of sodium:potassium-exchanging ATPase activity|up regulation of (Na+ + K+)-activated ATPase activity|upregulation of sodium/potassium-exchanging ATPase activity|up-regulation of Na,K-pump|activation of sodium:potassium-exchanging ATPase activity|up regulation of Na+,K+-ATPase activity|up regulation of Na+,K+ pump|upregulation of sodium:potassium exchanging ATPase activity|up regulation of Na(+)/K(+)-exchanging ATPase activity|up regulation of Na+/K+-exchanging ATPase activity|up-regulation of (Na+ + K+)-ATPase activity|activation of Na+/K+-exchanging ATPase activity|positive regulation of Na(+)/K(+)-exchanging ATPase activity|activation of Na(+)/K(+)-exchanging ATPase activity|positive regulation of Na+,K+ pump|positive regulation of Na+/K+-exchanging ATPase activity|activation of (Na+ + K+)-ATPase activity|up-regulation of Na,K-activated ATPase activity|positive regulation of ATP phosphohydrolase (Na+/K+-exchanging)|activation of Na,K-activated ATPase activity|upregulation of sodium/potassium-transporting ATPase activity|up regulation of ATP phosphohydrolase (Na+/K+-exchanging)|upregulation of Na+/K+-ATPase activity|upregulation of Na(+)/K(+)-ATPase activity http://purl.obolibrary.org/obo/GO_1903408 GO:0000269 biolink:MolecularActivity toxin export channel activity Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0000269 GO:0000268 biolink:MolecularActivity peroxisome targeting sequence binding Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome. go-plus.json peroxisome targeting signal receptor|PTS binding|PTS receptor http://purl.obolibrary.org/obo/GO_0000268 GO:1903407 biolink:BiologicalProcess negative regulation of P-type sodium:potassium-exchanging transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity. go-plus.json down regulation of sodium/potassium-transporting ATPase activity|inhibition of Na+,K+-ATPase activity|downregulation of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of (Na+ + K+)-ATPase activity|down-regulation of (Na+ + K+)-ATPase activity|down-regulation of Na,K-activated ATPase activity|down regulation of Na,K-pump|negative regulation of Na,K-activated ATPase activity|inhibition of sodium:potassium-exchanging ATPase activity|downregulation of sodium/potassium-transporting ATPase activity|down regulation of ATP phosphohydrolase (Na+/K+-exchanging)|inhibition of Na+/K+-exchanging ATPase activity|inhibition of Na(+)/K(+)-exchanging ATPase activity|downregulation of Na,K-pump|inhibition of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of sodium/potassium-exchanging ATPase activity|down-regulation of sodium/potassium-exchanging ATPase activity|negative regulation of sodium:potassium exchanging ATPase activity|down-regulation of sodium:potassium exchanging ATPase activity|downregulation of (Na+ + K+)-ATPase activity|inhibition of Na+,K+ pump|downregulation of Na,K-activated ATPase activity|negative regulation of sodium:potassium-exchanging ATPase activity|inhibition of sodium/potassium-exchanging ATPase activity|negative regulation of sodium/potassium-transporting ATPase activity|down-regulation of sodium/potassium-transporting ATPase activity|negative regulation of Na(+)/K(+)-ATPase activity|down-regulation of Na(+)/K(+)-ATPase activity|down-regulation of Na+/K+-ATPase activity|down regulation of sodium:potassium-exchanging ATPase activity|negative regulation of Na+/K+-ATPase activity|down regulation of (Na+ + K+)-ATPase activity|down regulation of Na,K-activated ATPase activity|down-regulation of Na,K-pump|inhibition of sodium:potassium exchanging ATPase activity|negative regulation of Na,K-pump|down-regulation of (Na+ + K+)-activated ATPase activity|negative regulation of (Na+ + K+)-activated ATPase activity|inhibition of (Na+ + K+)-ATPase activity|down regulation of Na+/K+-exchanging ATPase activity|negative regulation of Na+,K+-ATPase activity|down regulation of Na+,K+ pump|down regulation of Na(+)/K(+)-exchanging ATPase activity|down-regulation of Na+,K+-ATPase activity|inhibition of Na,K-activated ATPase activity|downregulation of sodium:potassium-exchanging ATPase activity|inhibition of sodium/potassium-transporting ATPase activity|downregulation of Na+/K+-exchanging ATPase activity|downregulation of Na+,K+ pump|downregulation of Na(+)/K(+)-exchanging ATPase activity|downregulation of Na+/K+-ATPase activity|down-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of ATP phosphohydrolase (Na+/K+-exchanging)|downregulation of Na(+)/K(+)-ATPase activity|down regulation of sodium/potassium-exchanging ATPase activity|downregulation of (Na+ + K+)-activated ATPase activity|downregulation of Na+,K+-ATPase activity|down regulation of Na(+)/K(+)-ATPase activity|down regulation of Na+/K+-ATPase activity|inhibition of Na,K-pump|down regulation of sodium:potassium exchanging ATPase activity|down-regulation of sodium:potassium-exchanging ATPase activity|downregulation of sodium/potassium-exchanging ATPase activity|inhibition of Na+/K+-ATPase activity|inhibition of Na(+)/K(+)-ATPase activity|down regulation of (Na+ + K+)-activated ATPase activity|down-regulation of Na+/K+-exchanging ATPase activity|down-regulation of Na+,K+ pump|negative regulation of Na+,K+ pump|negative regulation of Na(+)/K(+)-exchanging ATPase activity|down-regulation of Na(+)/K(+)-exchanging ATPase activity|negative regulation of Na+/K+-exchanging ATPase activity|down regulation of Na+,K+-ATPase activity|inhibition of (Na+ + K+)-activated ATPase activity|downregulation of sodium:potassium exchanging ATPase activity http://purl.obolibrary.org/obo/GO_1903407 CHEBI:87163 biolink:ChemicalSubstance dihydroisopentenyldehydrorhodopin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87163 chebi_ph7_3 GO:0000267 biolink:CellularComponent obsolete cell fraction OBSOLETE. A generic term for parts of cells prepared by disruptive biochemical techniques. go-plus.json cell fraction http://purl.obolibrary.org/obo/GO_0000267 CHEBI:87162 biolink:ChemicalSubstance isopentenyldehydrorhodopin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87162 chebi_ph7_3 GO:1903406 biolink:BiologicalProcess regulation of P-type sodium:potassium-exchanging transporter activity Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity. go-plus.json regulation of sodium:potassium-exchanging ATPase activity|regulation of sodium/potassium-transporting ATPase activity|regulation of ATP phosphohydrolase (Na+/K+-exchanging)|regulation of Na,K-pump|regulation of (Na+ + K+)-ATPase activity|regulation of Na,K-activated ATPase activity|regulation of Na(+)/K(+)-exchanging ATPase activity|regulation of Na+/K+-exchanging ATPase activity|regulation of Na+,K+ pump|regulation of Na(+)/K(+)-ATPase activity|regulation of Na+/K+-ATPase activity|regulation of (Na+ + K+)-activated ATPase activity|regulation of sodium/potassium-exchanging ATPase activity|regulation of Na+,K+-ATPase activity|regulation of sodium:potassium exchanging ATPase activity|regulation of sodium pump http://purl.obolibrary.org/obo/GO_1903406 CHEBI:63191 biolink:ChemicalSubstance beta-caryophyllene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63191 GO:1903405 biolink:BiologicalProcess protein localization to nuclear body A process in which a protein is transported to, or maintained in, a location within a nuclear body. go-plus.json protein localization in nuclear body|protein localisation to nuclear body|protein localisation in nuclear body http://purl.obolibrary.org/obo/GO_1903405 CHEBI:87165 biolink:ChemicalSubstance C50 carotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87165 GO:1903404 biolink:BiologicalProcess positive regulation of renal phosphate excretion Any process that activates or increases the frequency, rate or extent of renal phosphate excretion. go-plus.json upregulation of renal phosphate excretion|up regulation of renal phosphate ion excretion|activation of renal phosphate ion excretion|positive regulation of renal phosphate ion excretion|up regulation of renal phosphate excretion|activation of renal phosphate excretion|up-regulation of renal phosphate ion excretion|up-regulation of renal phosphate excretion|upregulation of renal phosphate ion excretion http://purl.obolibrary.org/obo/GO_1903404 CHEBI:87164 biolink:ChemicalSubstance 6-hydroxy-N-methylmyosmine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87164 chebi_ph7_3 GO:1903403 biolink:BiologicalProcess negative regulation of renal phosphate excretion Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion. go-plus.json downregulation of renal phosphate ion excretion|down regulation of renal phosphate excretion|downregulation of renal phosphate excretion|down-regulation of renal phosphate ion excretion|negative regulation of renal phosphate ion excretion|inhibition of renal phosphate ion excretion|down-regulation of renal phosphate excretion|inhibition of renal phosphate excretion|down regulation of renal phosphate ion excretion http://purl.obolibrary.org/obo/GO_1903403 CHEBI:87167 biolink:ChemicalSubstance S-[(2E,6E)-farnesyl]-L-cysteine methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_87167 CHEBI:63196 biolink:ChemicalSubstance (+)-caryolan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63196 chebi_ph7_3 GO:0048249 biolink:MolecularActivity high-affinity phosphate transmembrane transporter activity Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity phosphate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0048249 GO:1903402 biolink:BiologicalProcess regulation of renal phosphate excretion Any process that modulates the frequency, rate or extent of renal phosphate excretion. go-plus.json regulation of renal phosphate ion excretion http://purl.obolibrary.org/obo/GO_1903402 GO:1903401 biolink:BiologicalProcess L-lysine transmembrane transport The directed movement of L-lysine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903401 CHEBI:87169 biolink:ChemicalSubstance S-sulfo-L-cysteine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87169 chebi_ph7_3 GO:0000262 biolink:CellularComponent mitochondrial chromosome A chromosome found in the mitochondrion of a eukaryotic cell. NIF_Subcellular:sao1186327184 go-plus.json mtDNA|mitochondrial DNA|mitochondrial genome http://purl.obolibrary.org/obo/GO_0000262 GO:0048248 biolink:MolecularActivity CXCR3 chemokine receptor binding Binding to a CXCR3 chemokine receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0048248 GO:1903400 biolink:BiologicalProcess L-arginine transmembrane transport The directed movement of L-arginine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903400 GO:0000261 biolink:MolecularActivity obsolete sodium-translocating V-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in vacuoles of eukaryotes and in bacteria. go-plus.json sodium-translocating V-type ATPase activity http://purl.obolibrary.org/obo/GO_0000261 GO:0048247 biolink:BiologicalProcess lymphocyte chemotaxis The directed movement of a lymphocyte in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0048247 CHEBI:87168 biolink:ChemicalSubstance C45 carotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87168 GO:0000260 biolink:MolecularActivity obsolete hydrogen-translocating V-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H(+)(in) = ADP + phosphate + H+(out). Found in vacuoles of eukaryotes and in bacteria. go-plus.json hydrogen-translocating V-type ATPase activity http://purl.obolibrary.org/obo/GO_0000260 GO:0048246 biolink:BiologicalProcess macrophage chemotaxis The movement of a macrophage in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0048246 GO:0048245 biolink:BiologicalProcess eosinophil chemotaxis The movement of an eosinophil in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0048245 CHEBI:133556 biolink:ChemicalSubstance oxooctadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133556 chebi_ph7_3 CHEBI:133558 biolink:ChemicalSubstance hydroperoxyoctadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133558 CHEBI:133557 biolink:ChemicalSubstance hydroperoxyoctadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133557 CHEBI:38187 biolink:ChemicalSubstance pyridinecarbaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_38187 CHEBI:38186 biolink:ChemicalSubstance isonicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38186 chebi_ph7_3 CHEBI:38184 biolink:ChemicalSubstance picolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38184 chebi_ph7_3 CHEBI:38189 biolink:ChemicalSubstance pyridine N-oxides go-plus.json http://purl.obolibrary.org/obo/CHEBI_38189 CHEBI:38188 biolink:ChemicalSubstance pyridinium salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_38188 GO:0000277 biolink:MolecularActivity [cytochrome c]-lysine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c. RHEA:24312|MetaCyc:2.1.1.59-RXN|EC:2.1.1.59 go-plus.json cytochrome c-specific protein methylase III activity|cytochrome c methyltransferase activity|cytochrome c-specific protein-lysine methyltransferase activity|cytochrome c (lysine) methyltransferase activity|cytochrome c-lysine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity http://purl.obolibrary.org/obo/GO_0000277 GO:0048255 biolink:BiologicalProcess mRNA stabilization Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0048255 GO:0048254 biolink:BiologicalProcess snoRNA localization Any process in which small nucleolar RNA is transported to, or maintained in, a specific location. go-plus.json snoRNA localisation|small nucleolar RNA localization|establishment and maintenance of snoRNA localization http://purl.obolibrary.org/obo/GO_0048254 GO:0000276 biolink:CellularComponent mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0000276 GO:0000275 biolink:CellularComponent mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled. go-plus.json hydrogen-transporting ATP synthase, F1 sector|proton-transporting ATP synthase complex, catalytic core F(1) http://purl.obolibrary.org/obo/GO_0000275 GO:0048253 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048253 GO:0000274 biolink:CellularComponent mitochondrial proton-transporting ATP synthase, stator stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. go-plus.json mitochondrial proton-transporting ATP synthase, peripheral stalk http://purl.obolibrary.org/obo/GO_0000274 GO:0048252 biolink:BiologicalProcess lauric acid metabolic process The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources. go-plus.json n-dodecanoic acid metabolic process|lauric acid metabolism|n-dodecanoic acid metabolism http://purl.obolibrary.org/obo/GO_0048252 GO:0048251 biolink:BiologicalProcess elastic fiber assembly Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. go-plus.json elastin fiber assembly|elastin fibre assembly|elastic fibre assembly http://purl.obolibrary.org/obo/GO_0048251 GO:1903419 biolink:BiologicalProcess protein localization to cortical endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum. go-plus.json protein localisation in cortical endoplasmic reticulum|protein localization in cortical endoplasmic reticulum|protein localization to cortical ER|protein localisation to cortical endoplasmic reticulum http://purl.obolibrary.org/obo/GO_1903419 GO:0048250 biolink:BiologicalProcess iron import into the mitochondrion The process in which iron is transported from the cytosol into the mitochondrial matrix. go-plus.json mitochondrial iron ion transport|mitochondrial iron transport|mitochondrial iron ion transmembrane transport|mitochondrial iron cation transmembrane transport http://purl.obolibrary.org/obo/GO_0048250 GO:1903418 biolink:BiologicalProcess protein localization to plasma membrane of cell tip A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip. go-plus.json protein localisation to plasma membrane of cell tip|protein localization in plasma membrane of cell tip|protein localisation in plasma membrane of cell tip http://purl.obolibrary.org/obo/GO_1903418 GO:0000279 biolink:BiologicalProcess M phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. Wikipedia:M_phase go-plus.json M-phase http://purl.obolibrary.org/obo/GO_0000279 gocheck_do_not_annotate GO:0000278 biolink:BiologicalProcess mitotic cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. Wikipedia:Mitosis go-plus.json mitosis http://purl.obolibrary.org/obo/GO_0000278 goslim_chembl|goslim_yeast|goslim_drosophila|goslim_generic GO:1903416 biolink:BiologicalProcess response to glycoside Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus. go-plus.json cellular response to ouabain http://purl.obolibrary.org/obo/GO_1903416 GO:1903415 biolink:BiologicalProcess flavonoid transport from endoplasmic reticulum to plant-type vacuole The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole. go-plus.json flavonoid accumulation in vacuole http://purl.obolibrary.org/obo/GO_1903415 GO:1903414 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903414 GO:1903413 biolink:BiologicalProcess cellular response to bile acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903413 GO:0048259 biolink:BiologicalProcess regulation of receptor-mediated endocytosis Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. go-plus.json regulation of receptor mediated endocytosis http://purl.obolibrary.org/obo/GO_0048259 GO:1903412 biolink:BiologicalProcess response to bile acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903412 GO:0000273 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000273 GO:0000272 biolink:BiologicalProcess polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json multicellular organismal polysaccharide catabolic process|polysaccharide degradation|polysaccharide breakdown|polysaccharide catabolism http://purl.obolibrary.org/obo/GO_0000272 GO:1903411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903411 GO:0048258 biolink:MolecularActivity 3-ketoglucose-reductase activity Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose. MetaCyc:KETOGLUCOSE-REDUCTASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0048258 GO:0000271 biolink:BiologicalProcess polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. go-plus.json glycan biosynthesis|glycan biosynthetic process|polysaccharide anabolism|polysaccharide biosynthesis|polysaccharide synthesis|polysaccharide formation http://purl.obolibrary.org/obo/GO_0000271 GO:1903410 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903410 GO:0048257 biolink:MolecularActivity 3'-flap endonuclease activity Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis. go-plus.json 3' flap endonuclease activity http://purl.obolibrary.org/obo/GO_0048257 GO:0048256 biolink:MolecularActivity flap endonuclease activity Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0048256 GO:0000270 biolink:BiologicalProcess peptidoglycan metabolic process The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network. go-plus.json peptidoglycan metabolism|murein metabolism|murein metabolic process http://purl.obolibrary.org/obo/GO_0000270 CHEBI:38198 biolink:ChemicalSubstance aminoalkylpyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38198 CHEBI:38197 biolink:ChemicalSubstance furopyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38197 CHEBI:38196 biolink:ChemicalSubstance hydroxymethylpyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38196 GO:0048266 biolink:BiologicalProcess behavioral response to pain Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. go-plus.json behavioural response to pain http://purl.obolibrary.org/obo/GO_0048266 GO:0000244 biolink:BiologicalProcess spliceosomal tri-snRNP complex assembly The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex. go-plus.json spliceosomal tri-snRNP assembly|snRNP recycling|assembly of spliceosomal tri-snRNP U4atac/U6atac.U5|assembly of spliceosomal tri-snRNP U4/U6.U5|spliceosomal tri-snRNP U4/U6.U5 assembly|spliceosomal tri-snRNP U4atac/U6atac.U5 assembly|assembly of spliceosomal tri-snRNP http://purl.obolibrary.org/obo/GO_0000244 GO:0000243 biolink:CellularComponent commitment complex A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript. go-plus.json mammalian spliceosomal E complex|yeast spliceosomal complex CC|mammalian spliceosomal complex E http://purl.obolibrary.org/obo/GO_0000243 GO:0048265 biolink:BiologicalProcess response to pain Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. go-plus.json physiological response to pain http://purl.obolibrary.org/obo/GO_0048265 GO:0000242 biolink:CellularComponent pericentriolar material A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000242 GO:0048264 biolink:BiologicalProcess determination of ventral identity The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json determination of abaxial identity http://purl.obolibrary.org/obo/GO_0048264 CHEBI:87181 biolink:ChemicalSubstance (2R)-2,6-dimethylheptanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87181 GO:0000241 biolink:BiologicalProcess diakinesis The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred. Wikipedia:Meiosis#Diakinesis|Wikipedia:Diakinesis go-plus.json http://purl.obolibrary.org/obo/GO_0000241 gocheck_do_not_annotate GO:0048263 biolink:BiologicalProcess determination of dorsal identity Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json determination of adaxial identity http://purl.obolibrary.org/obo/GO_0048263 CHEBI:38172 biolink:ChemicalSubstance monohydroxy-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38172 GO:0048262 biolink:BiologicalProcess determination of dorsal/ventral asymmetry Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis. go-plus.json determination of dorsal-ventral asymmetry|determination of dorsoventral asymmetry|determination of adaxial/abaxial asymmetry http://purl.obolibrary.org/obo/GO_0048262 GO:0000248 biolink:MolecularActivity C-5 sterol desaturase activity Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+. Reactome:R-HSA-6807053|Reactome:R-HSA-195664 go-plus.json sterol-C5-desaturase activity http://purl.obolibrary.org/obo/GO_0000248 GO:0048261 biolink:BiologicalProcess negative regulation of receptor-mediated endocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. go-plus.json down regulation of receptor mediated endocytosis|downregulation of receptor mediated endocytosis|down-regulation of receptor mediated endocytosis|negative regulation of receptor mediated endocytosis|inhibition of receptor mediated endocytosis http://purl.obolibrary.org/obo/GO_0048261 GO:0000247 biolink:MolecularActivity C-8 sterol isomerase activity Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols. go-plus.json delta-8-delta-7 sterol isomerase activity http://purl.obolibrary.org/obo/GO_0000247 CHEBI:87182 biolink:ChemicalSubstance (2S)-2,6-dimethylheptanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87182 GO:1903429 biolink:BiologicalProcess regulation of cell maturation Any process that modulates the frequency, rate or extent of cell maturation. go-plus.json regulation of functional differentiation http://purl.obolibrary.org/obo/GO_1903429 GO:0048260 biolink:BiologicalProcess positive regulation of receptor-mediated endocytosis Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. go-plus.json positive regulation of receptor mediated endocytosis|up regulation of receptor mediated endocytosis|activation of receptor mediated endocytosis|stimulation of receptor mediated endocytosis|up-regulation of receptor mediated endocytosis|upregulation of receptor mediated endocytosis http://purl.obolibrary.org/obo/GO_0048260 GO:0000246 biolink:MolecularActivity delta24(24-1) sterol reductase activity Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH. KEGG_REACTION:R05641|RHEA:18501|MetaCyc:1.3.1.71-RXN|EC:1.3.1.71 go-plus.json sterol delta-24(28) reductase activity|ergosterol:NADP+ delta24(241)-oxidoreductase activity|sterol delta24(28)-methylene reductase activity|delta24(241)-sterol reductase activity|sterol delta24(28)-reductase activity|sterol Delta(24(28))-methylene reductase activity|D24(24-1)-sterol reductase activity|sterol Delta(24(28))-reductase activity|C-24(28) sterol reductase activity|sterol delta-24(28) methylene reductase activity http://purl.obolibrary.org/obo/GO_0000246 CHEBI:38170 biolink:ChemicalSubstance diamino-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38170 GO:1903428 biolink:BiologicalProcess positive regulation of reactive oxygen species biosynthetic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process. go-plus.json upregulation of ROS generation|up regulation of ROS formation|positive regulation of reactive oxygen species generation|upregulation of reactive oxygen species synthesis|up regulation of reactive oxygen species generation|positive regulation of ROS formation|upregulation of reactive oxygen species formation|up regulation of reactive oxygen species anabolism|activation of ROS formation|positive regulation of reactive oxygen species biosynthesis|up-regulation of ROS generation|positive regulation of reactive oxygen species anabolism|activation of reactive oxygen species anabolism|up regulation of reactive oxygen species biosynthesis|up regulation of reactive oxygen species biosynthetic process|up regulation of reactive oxygen species synthesis|upregulation of reactive oxygen species generation|positive regulation of reactive oxygen species synthesis|up-regulation of ROS formation|activation of reactive oxygen species synthesis|activation of ROS generation|up regulation of reactive oxygen species formation|positive regulation of reactive oxygen species formation|activation of reactive oxygen species formation|positive regulation of ROS generation|upregulation of reactive oxygen species biosynthetic process|upregulation of reactive oxygen species biosynthesis|up-regulation of reactive oxygen species anabolism|up-regulation of reactive oxygen species generation|up regulation of ROS generation|upregulation of ROS formation|up-regulation of reactive oxygen species synthesis|up-regulation of reactive oxygen species formation|activation of reactive oxygen species generation|up-regulation of reactive oxygen species biosynthetic process|up-regulation of reactive oxygen species biosynthesis|upregulation of reactive oxygen species anabolism|activation of reactive oxygen species biosynthetic process|activation of reactive oxygen species biosynthesis http://purl.obolibrary.org/obo/GO_1903428 GO:0000245 biolink:BiologicalProcess spliceosomal complex assembly The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. go-plus.json spliceosome assembly http://purl.obolibrary.org/obo/GO_0000245 GO:1903427 biolink:BiologicalProcess negative regulation of reactive oxygen species biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. go-plus.json prevention of ROS generation|down regulation of reactive oxygen species anabolism|down-regulation of reactive oxygen species biosynthetic process|down-regulation of reactive oxygen species biosynthesis|inhibition of ROS generation|negative regulation of reactive oxygen species biosynthesis|down regulation of reactive oxygen species synthesis|downregulation of reactive oxygen species anabolism|downregulation of reactive oxygen species generation|down-regulation of ROS formation|negative regulation of ROS formation|down regulation of reactive oxygen species formation|downregulation of reactive oxygen species synthesis|down regulation of reactive oxygen species generation|downregulation of reactive oxygen species formation|downregulation of reactive oxygen species biosynthesis|downregulation of reactive oxygen species biosynthetic process|down-regulation of reactive oxygen species anabolism|negative regulation of reactive oxygen species anabolism|negative regulation of ROS generation|down-regulation of ROS generation|down regulation of reactive oxygen species biosynthesis|down regulation of reactive oxygen species biosynthetic process|inhibition of reactive oxygen species generation|down-regulation of reactive oxygen species synthesis|negative regulation of reactive oxygen species synthesis|inhibition of reactive oxygen species biosynthetic process|inhibition of reactive oxygen species biosynthesis|inhibition of ROS formation|inhibition of reactive oxygen species anabolism|down-regulation of reactive oxygen species formation|negative regulation of reactive oxygen species formation|inhibition of reactive oxygen species synthesis|downregulation of ROS generation|down regulation of ROS formation|inhibition of reactive oxygen species formation|negative regulation of reactive oxygen species generation|down-regulation of reactive oxygen species generation|down regulation of ROS generation|downregulation of ROS formation http://purl.obolibrary.org/obo/GO_1903427 CHEBI:133538 biolink:ChemicalSubstance L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133538 GO:1903426 biolink:BiologicalProcess regulation of reactive oxygen species biosynthetic process Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. go-plus.json regulation of reactive oxygen species anabolism|regulation of reactive oxygen species synthesis|regulation of reactive oxygen species generation|regulation of reactive oxygen species formation|regulation of reactive oxygen species biosynthesis|regulation of ROS generation|regulation of ROS formation http://purl.obolibrary.org/obo/GO_1903426 GO:1903425 biolink:MolecularActivity fluoride transmembrane transporter activity Enables the transfer of fluoride from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_1903425 GO:1903424 biolink:BiologicalProcess fluoride transmembrane transport The process in which fluoride is transported across a membrane. go-plus.json transmembrane fluoride transport|fluoride membrane transport http://purl.obolibrary.org/obo/GO_1903424 CHEBI:133539 biolink:ChemicalSubstance hydroxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133539 GO:0000240 biolink:BiologicalProcess diplotene The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves. Wikipedia:Diplotene|Wikipedia:Meiosis#Diplotene go-plus.json http://purl.obolibrary.org/obo/GO_0000240 gocheck_do_not_annotate GO:1903423 biolink:BiologicalProcess positive regulation of synaptic vesicle recycling Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling. go-plus.json up regulation of kiss-and-run synaptic vesicle recycling|activation of kiss-and-stay synaptic vesicle recycling|positive regulation of kiss-and-run synaptic vesicle recycling|activation of synaptic vesicle recycling|up-regulation of synaptic vesicle recycling|positive regulation of kiss-and-stay synaptic vesicle recycling|activation of kiss-and-run synaptic vesicle recycling|up regulation of kiss-and-stay synaptic vesicle recycling|up-regulation of kiss-and-run synaptic vesicle recycling|up regulation of synaptic vesicle recycling|upregulation of kiss-and-stay synaptic vesicle recycling|upregulation of kiss-and-run synaptic vesicle recycling|upregulation of synaptic vesicle recycling|up-regulation of kiss-and-stay synaptic vesicle recycling http://purl.obolibrary.org/obo/GO_1903423 GO:1903422 biolink:BiologicalProcess negative regulation of synaptic vesicle recycling Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling. go-plus.json downregulation of kiss-and-run synaptic vesicle recycling|negative regulation of kiss-and-stay synaptic vesicle recycling|down-regulation of kiss-and-stay synaptic vesicle recycling|negative regulation of kiss-and-run synaptic vesicle recycling|down-regulation of kiss-and-run synaptic vesicle recycling|down-regulation of synaptic vesicle recycling|downregulation of kiss-and-stay synaptic vesicle recycling|down regulation of kiss-and-stay synaptic vesicle recycling|downregulation of synaptic vesicle recycling|inhibition of kiss-and-run synaptic vesicle recycling|down regulation of synaptic vesicle recycling|inhibition of kiss-and-stay synaptic vesicle recycling|inhibition of synaptic vesicle recycling|down regulation of kiss-and-run synaptic vesicle recycling http://purl.obolibrary.org/obo/GO_1903422 GO:0048269 biolink:CellularComponent methionine adenosyltransferase complex A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules. go-plus.json MAT complex http://purl.obolibrary.org/obo/GO_0048269 GO:0048268 biolink:BiologicalProcess clathrin coat assembly The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage. go-plus.json clathrin cage assembly http://purl.obolibrary.org/obo/GO_0048268 GO:1903421 biolink:BiologicalProcess regulation of synaptic vesicle recycling Any process that modulates the frequency, rate or extent of synaptic vesicle recycling. go-plus.json regulation of kiss-and-stay synaptic vesicle recycling|regulation of kiss-and-run synaptic vesicle recycling http://purl.obolibrary.org/obo/GO_1903421 GO:1903420 biolink:BiologicalProcess protein localization to endoplasmic reticulum tubular network A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network. go-plus.json protein localisation to endoplasmic reticulum tubular network|protein localization in endoplasmic reticulum tubular network|protein localization to tubular ER|protein localisation in endoplasmic reticulum tubular network http://purl.obolibrary.org/obo/GO_1903420 GO:0048267 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048267 GO:1903430 biolink:BiologicalProcess negative regulation of cell maturation Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. go-plus.json down regulation of functional differentiation|inhibition of cell maturation|inhibition of functional differentiation|down regulation of cell maturation|down-regulation of functional differentiation|negative regulation of functional differentiation|downregulation of cell maturation|downregulation of functional differentiation|down-regulation of cell maturation http://purl.obolibrary.org/obo/GO_1903430 GO:0014885 biolink:BiologicalProcess detection of injury involved in regulation of muscle adaptation The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. go-plus.json detection of injury involved in regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014885 GO:0014884 biolink:BiologicalProcess detection of muscle inactivity involved in regulation of muscle adaptation The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. go-plus.json http://purl.obolibrary.org/obo/GO_0014884 GO:0014883 biolink:BiologicalProcess transition between fast and slow fiber The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation. go-plus.json transition fast-slow fibre|transition fast-slow fiber|transition between fast and slow fibre http://purl.obolibrary.org/obo/GO_0014883 GO:0014882 biolink:BiologicalProcess regulation of myofibril number Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. go-plus.json change of myofibril number http://purl.obolibrary.org/obo/GO_0014882 NCBITaxon:2058185 biolink:OrganismalEntity Dictyosteliaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2058185 GO:0014889 biolink:BiologicalProcess muscle atrophy A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. Wikipedia:Muscle_atrophy go-plus.json http://purl.obolibrary.org/obo/GO_0014889 GO:0014888 biolink:BiologicalProcess striated muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. go-plus.json striated muscle plasticity http://purl.obolibrary.org/obo/GO_0014888 GO:0014887 biolink:BiologicalProcess cardiac muscle adaptation The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. go-plus.json cardiac muscle plasticity http://purl.obolibrary.org/obo/GO_0014887 GO:0014886 biolink:BiologicalProcess transition between slow and fast fiber The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation. go-plus.json transition between slow and fast fibre|transition slow-fast fibre|transition slow-fast fiber http://purl.obolibrary.org/obo/GO_0014886 CHEBI:38165 biolink:ChemicalSubstance organic heterooctacyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38165 CHEBI:38164 biolink:ChemicalSubstance organic heteropentacyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38164 CHEBI:38163 biolink:ChemicalSubstance organic heterotetracyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38163 GO:0000249 biolink:MolecularActivity C-22 sterol desaturase activity Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+. go-plus.json http://purl.obolibrary.org/obo/GO_0000249 CHEBI:38169 biolink:ChemicalSubstance monoamino-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38169 GO:0014881 biolink:BiologicalProcess regulation of myofibril size Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. go-plus.json change of myofibril size http://purl.obolibrary.org/obo/GO_0014881 GO:0014880 biolink:BiologicalProcess regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014880 CHEBI:38168 biolink:ChemicalSubstance chloro-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38168 CHEBI:38166 biolink:ChemicalSubstance organic heteropolycyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38166 GO:0097200 biolink:MolecularActivity cysteine-type endopeptidase activity involved in execution phase of apoptosis Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis. go-plus.json executioner caspase activity|effector caspase activity http://purl.obolibrary.org/obo/GO_0097200 GO:0048277 biolink:BiologicalProcess obsolete nonexocytotic vesicle docking OBSOLETE. The initial attachment of a transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, during a non-exocytotic process. go-plus.json non-exocytotic vesicle docking|nonexocytotic vesicle docking http://purl.obolibrary.org/obo/GO_0048277 GO:0000255 biolink:BiologicalProcess allantoin metabolic process The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism. go-plus.json allantoin metabolism http://purl.obolibrary.org/obo/GO_0000255 GO:0000254 biolink:MolecularActivity C-4 methylsterol oxidase activity Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O. Reactome:R-HSA-194641|RHEA:55220|MetaCyc:1.14.13.72-RXN|EC:1.14.18.9|Reactome:R-HSA-194669 go-plus.json methylsterol monooxygenase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methylsterol hydroxylase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|4-methylsterol oxidase activity http://purl.obolibrary.org/obo/GO_0000254 GO:0048276 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048276 GO:0097202 biolink:BiologicalProcess activation of cysteine-type endopeptidase activity Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. go-plus.json activation of caspase activity|activation of metacaspase activity http://purl.obolibrary.org/obo/GO_0097202 GO:0000253 biolink:MolecularActivity 3-keto sterol reductase activity Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+). RHEA:18409|MetaCyc:RXN66-319|Reactome:R-HSA-194689|MetaCyc:RXN66-19|MetaCyc:RXN66-314|MetaCyc:1.1.1.270-RXN|Reactome:R-HSA-194632|MetaCyc:RXN66-24|EC:1.1.1.270|MetaCyc:RXN3O-4110 go-plus.json 3-KSR activity|3-keto-steroid reductase activity|3beta-hydroxy-steroid:NADP+ 3-oxidoreductase http://purl.obolibrary.org/obo/GO_0000253 CHEBI:87170 biolink:ChemicalSubstance 2-thiouridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87170 chebi_ph7_3 GO:0048275 biolink:BiologicalProcess N-terminal peptidyl-arginine acetylation The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase. RESID:AA0354 go-plus.json http://purl.obolibrary.org/obo/GO_0048275 GO:0000252 biolink:MolecularActivity C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H. Reactome:R-HSA-194642|Reactome:R-HSA-194718|EC:1.1.1.170 go-plus.json C-3 sterol dehydrogenase (C-4 decarboxylase) activity|3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity|C-3 sterol dehydrogenase activity|sterol 4alpha-carboxylic decarboxylase activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)|3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)|sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity http://purl.obolibrary.org/obo/GO_0000252 GO:0097201 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter in response to stress Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0097201 GO:0048274 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048274 GO:0048273 biolink:MolecularActivity mitogen-activated protein kinase p38 binding Binding to mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation. go-plus.json MAPK p38 binding http://purl.obolibrary.org/obo/GO_0048273 GO:0000259 biolink:MolecularActivity obsolete intracellular nucleoside transmembrane transporter activity OBSOLETE. Enables the directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide) within a cell. go-plus.json intracellular nucleoside transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0000259 CHEBI:87172 biolink:ChemicalSubstance 5-taurinomethyluridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87172 chebi_ph7_3 CHEBI:38183 biolink:ChemicalSubstance pyridone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38183 CHEBI:87171 biolink:ChemicalSubstance 5-taurinomethyl-2-thiouridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87171 chebi_ph7_3 GO:0000258 biolink:MolecularActivity obsolete isoleucine/valine:sodium symporter activity OBSOLETE. Catalysis of the reaction: (isoleucine or valine)(out) + Na+(out) = (isoleucine or valine)(in) + Na+(in). go-plus.json isoleucine/valine:sodium symporter activity http://purl.obolibrary.org/obo/GO_0000258 GO:0048272 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048272 CHEBI:38182 biolink:ChemicalSubstance monohydroxypyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38182 GO:0000257 biolink:MolecularActivity nitrilase activity Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides. UM-BBD_enzymeID:e0283|RHEA:21724|MetaCyc:3.5.5.1-RXN|KEGG_REACTION:R00540|EC:3.5.5.1 go-plus.json nitrile aminohydrolase activity|benzonitrilase activity|acetonitrilase activity http://purl.obolibrary.org/obo/GO_0000257 GO:0048271 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048271 CHEBI:38181 biolink:ChemicalSubstance pyridinemonocarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38181 CHEBI:87173 biolink:ChemicalSubstance (2R)-2-methyltetradecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87173 GO:1903439 biolink:CellularComponent calcitonin family receptor complex A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. go-plus.json http://purl.obolibrary.org/obo/GO_1903439 GO:0048270 biolink:MolecularActivity methionine adenosyltransferase regulator activity Binds to and modulates the activity of methionine adenosyltransferase. go-plus.json MAT regulator activity http://purl.obolibrary.org/obo/GO_0048270 GO:0000256 biolink:BiologicalProcess allantoin catabolic process The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. go-plus.json allantoin degradation|allantoin breakdown|allantoin catabolism http://purl.obolibrary.org/obo/GO_0000256 CHEBI:38180 biolink:ChemicalSubstance polycyclic heteroarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38180 CHEBI:133549 biolink:ChemicalSubstance N-acetyl-L-threoninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133549 chebi_ph7_3 GO:1903438 biolink:BiologicalProcess positive regulation of mitotic cytokinetic process Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process. go-plus.json up regulation of mitotic cytokinetic process|activation of mitotic cytokinetic process|up-regulation of mitotic cytokinetic process|upregulation of mitotic cytokinetic process http://purl.obolibrary.org/obo/GO_1903438 GO:1903437 biolink:BiologicalProcess negative regulation of mitotic cytokinetic process Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process. go-plus.json downregulation of mitotic cytokinetic process|down-regulation of mitotic cytokinetic process|inhibition of mitotic cytokinetic process|down regulation of mitotic cytokinetic process http://purl.obolibrary.org/obo/GO_1903437 GO:1903436 biolink:BiologicalProcess regulation of mitotic cytokinetic process Any process that modulates the frequency, rate or extent of mitotic cytokinetic process. go-plus.json http://purl.obolibrary.org/obo/GO_1903436 GO:1903435 biolink:BiologicalProcess positive regulation of constitutive secretory pathway Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway. go-plus.json up regulation of constitutive secretory pathway|upregulation of constitutive secretory pathway|up-regulation of constitutive secretory pathway|activation of constitutive secretory pathway http://purl.obolibrary.org/obo/GO_1903435 GO:1903434 biolink:BiologicalProcess negative regulation of constitutive secretory pathway Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway. go-plus.json downregulation of constitutive secretory pathway|down regulation of constitutive secretory pathway|inhibition of constitutive secretory pathway|down-regulation of constitutive secretory pathway http://purl.obolibrary.org/obo/GO_1903434 GO:0000251 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000251 GO:1903433 biolink:BiologicalProcess regulation of constitutive secretory pathway Any process that modulates the frequency, rate or extent of constitutive secretory pathway. go-plus.json http://purl.obolibrary.org/obo/GO_1903433 GO:0000250 biolink:MolecularActivity lanosterol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus. MetaCyc:LANOSTEROL-SYNTHASE-RXN|RHEA:14621|KEGG_REACTION:R03199|Reactome:R-HSA-191366|EC:5.4.99.7 go-plus.json 2,3-oxidosqualene-lanosterol cyclase activity|oxidosqualene-lanosterol cyclase activity|squalene 2,3-epoxide:lanosterol cyclase activity|oxidosqualene:lanosterol cyclase activity|2,3-oxidosqualene sterol cyclase activity|oxidosqualene--lanosterol cyclase activity|2,3-epoxysqualene--lanosterol cyclase activity|OSC|lanosterol 2,3-oxidosqualene cyclase activity|squalene-2,3-oxide-lanosterol cyclase activity|2,3-epoxysqualene lanosterol cyclase activity|squalene epoxidase-cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)|2,3-epoxysqualene-lanosterol cyclase activity http://purl.obolibrary.org/obo/GO_0000250 GO:0048279 biolink:BiologicalProcess vesicle fusion with endoplasmic reticulum The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum. go-plus.json vesicle fusion with ER http://purl.obolibrary.org/obo/GO_0048279 GO:1903432 biolink:BiologicalProcess regulation of TORC1 signaling Any process that modulates the frequency, rate or extent of TORC1 signaling. go-plus.json regulation of TORC1 signal transduction http://purl.obolibrary.org/obo/GO_1903432 GO:1903431 biolink:BiologicalProcess positive regulation of cell maturation Any process that activates or increases the frequency, rate or extent of cell maturation. go-plus.json upregulation of functional differentiation|up-regulation of cell maturation|upregulation of cell maturation|up-regulation of functional differentiation|activation of functional differentiation|up regulation of cell maturation|positive regulation of functional differentiation|activation of cell maturation|up regulation of functional differentiation http://purl.obolibrary.org/obo/GO_1903431 GO:0048278 biolink:BiologicalProcess vesicle docking The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere. go-plus.json vesicle to membrane docking http://purl.obolibrary.org/obo/GO_0048278 GO:0014896 biolink:BiologicalProcess muscle hypertrophy The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. Wikipedia:Muscle_hypertrophy go-plus.json http://purl.obolibrary.org/obo/GO_0014896 GO:1903441 biolink:BiologicalProcess protein localization to ciliary membrane A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. go-plus.json protein localization in ciliary membrane|protein localisation to ciliary membrane|protein localisation in ciliary membrane http://purl.obolibrary.org/obo/GO_1903441 GO:1903440 biolink:CellularComponent amylin receptor complex A protein complex which is capable of amylin receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903440 GO:0014895 biolink:BiologicalProcess smooth muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. go-plus.json http://purl.obolibrary.org/obo/GO_0014895 GO:0014894 biolink:BiologicalProcess response to denervation involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation. go-plus.json http://purl.obolibrary.org/obo/GO_0014894 GO:0014893 biolink:BiologicalProcess response to rest involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation. go-plus.json http://purl.obolibrary.org/obo/GO_0014893 GO:0014899 biolink:BiologicalProcess cardiac muscle atrophy A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation. go-plus.json http://purl.obolibrary.org/obo/GO_0014899 GO:0014898 biolink:BiologicalProcess cardiac muscle hypertrophy in response to stress The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0014898 GO:0014897 biolink:BiologicalProcess striated muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. go-plus.json http://purl.obolibrary.org/obo/GO_0014897 GO:0097208 biolink:CellularComponent alveolar lamellar body A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. go-plus.json http://purl.obolibrary.org/obo/GO_0097208 GO:0048280 biolink:BiologicalProcess vesicle fusion with Golgi apparatus The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. go-plus.json http://purl.obolibrary.org/obo/GO_0048280 GO:0097207 biolink:BiologicalProcess bud dormancy process A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud. go-plus.json bud dormancy http://purl.obolibrary.org/obo/GO_0097207 CHEBI:38175 biolink:ChemicalSubstance triamino-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38175 CHEBI:53794 biolink:ChemicalSubstance (4-hydroxy-3-nitrophenyl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53794 CHEBI:38173 biolink:ChemicalSubstance dihydroxy-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38173 GO:0097209 biolink:CellularComponent epidermal lamellar body A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. go-plus.json http://purl.obolibrary.org/obo/GO_0097209 GO:0097204 biolink:CellularComponent phagocytic cup base The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking. go-plus.json http://purl.obolibrary.org/obo/GO_0097204 GO:0097203 biolink:CellularComponent phagocytic cup lip The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome. go-plus.json http://purl.obolibrary.org/obo/GO_0097203 CHEBI:38179 biolink:ChemicalSubstance monocyclic heteroarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38179 GO:0014891 biolink:BiologicalProcess striated muscle atrophy A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014891 GO:0097206 biolink:BiologicalProcess nephrocyte filtration The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm. go-plus.json http://purl.obolibrary.org/obo/GO_0097206 GO:0014890 biolink:BiologicalProcess smooth muscle atrophy A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. go-plus.json http://purl.obolibrary.org/obo/GO_0014890 GO:0097205 biolink:BiologicalProcess renal filtration A renal system process in which fluid circulating through the body is filtered through a barrier system. go-plus.json http://purl.obolibrary.org/obo/GO_0097205 GO:0000222 biolink:CellularComponent plasma membrane proton-transporting V-type ATPase, V0 domain The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane. go-plus.json plasma membrane hydrogen ion-transporting ATPase V0 domain http://purl.obolibrary.org/obo/GO_0000222 GO:0048288 biolink:BiologicalProcess nuclear membrane fusion involved in karyogamy The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. go-plus.json nuclear membrane fusion during karyogamy http://purl.obolibrary.org/obo/GO_0048288 GO:0000221 biolink:CellularComponent vacuolar proton-transporting V-type ATPase, V1 domain The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. go-plus.json vacuolar hydrogen ion-transporting ATPase V1 domain http://purl.obolibrary.org/obo/GO_0000221 GO:0048287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048287 GO:0000220 biolink:CellularComponent vacuolar proton-transporting V-type ATPase, V0 domain The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. go-plus.json vacuolar hydrogen ion-transporting ATPase V0 domain http://purl.obolibrary.org/obo/GO_0000220 GO:0048286 biolink:BiologicalProcess lung alveolus development The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways. go-plus.json alveolarization|alveologenesis http://purl.obolibrary.org/obo/GO_0048286 GO:0048285 biolink:BiologicalProcess organelle fission The creation of two or more organelles by division of one organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0048285 goslim_yeast|goslim_pir GO:0000226 biolink:BiologicalProcess microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. go-plus.json microtubule dynamics|microtubule cytoskeleton organisation|microtubule cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0000226 goslim_drosophila|goslim_pombe GO:0048284 biolink:BiologicalProcess organelle fusion The creation of a single organelle from two or more organelles. go-plus.json http://purl.obolibrary.org/obo/GO_0048284 goslim_yeast|goslim_pir CHEBI:38150 biolink:ChemicalSubstance enterobactin(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_38150 GO:0000225 biolink:MolecularActivity N-acetylglucosaminylphosphatidylinositol deacetylase activity Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. RHEA:11660|MetaCyc:3.1.1.69-RXN|EC:3.5.1.89|Reactome:R-HSA-162857 go-plus.json N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity|GlcNAc-PI deacetylase activity|N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity|GlcNAc-PI de-N-acetylase activity|acetylglucosaminylphosphatidylinositol deacetylase activity|6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0000225 GO:0048283 biolink:BiologicalProcess indeterminate inflorescence morphogenesis The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems. go-plus.json http://purl.obolibrary.org/obo/GO_0048283 GO:0000224 biolink:MolecularActivity peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. EC:3.5.1.52|Reactome:R-HSA-8850594|MetaCyc:3.5.1.52-RXN go-plus.json glycopeptidase activity|N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity|PNGase|peptide:N-glycanase|N-oligosaccharide glycopeptidase activity|N-glycanase activity|glycopeptide N-glycosidase activity|PNGase F|jack-bean glycopeptidase|PNGase A http://purl.obolibrary.org/obo/GO_0000224 GO:0048282 biolink:BiologicalProcess determinate inflorescence morphogenesis The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems. go-plus.json http://purl.obolibrary.org/obo/GO_0048282 GO:0000223 biolink:CellularComponent plasma membrane proton-transporting V-type ATPase, V1 domain The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane. go-plus.json plasma membrane hydrogen ion-transporting ATPase V1 domain http://purl.obolibrary.org/obo/GO_0000223 GO:0048281 biolink:BiologicalProcess inflorescence morphogenesis The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers. go-plus.json http://purl.obolibrary.org/obo/GO_0048281 GO:1903449 biolink:BiologicalProcess androst-4-ene-3,17-dione biosynthetic process The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione. go-plus.json androst-4-ene-3,17-dione synthesis|androst-4-ene-3,17-dione formation|androstenedione biosynthetic process|androst-4-ene-3,17-dione biosynthesis|androst-4-ene-3,17-dione anabolism http://purl.obolibrary.org/obo/GO_1903449 GO:1903448 biolink:BiologicalProcess geraniol biosynthetic process The chemical reactions and pathways resulting in the formation of geraniol. go-plus.json geraniol biosynthesis|geraniol anabolism|geraniol synthesis|geraniol formation http://purl.obolibrary.org/obo/GO_1903448 GO:0014869 biolink:BiologicalProcess detection of muscle inactivity The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0014869 GO:1903447 biolink:BiologicalProcess geraniol catabolic process The chemical reactions and pathways resulting in the breakdown of geraniol. go-plus.json geraniol breakdown|geraniol degradation|geraniol catabolism http://purl.obolibrary.org/obo/GO_1903447 CHEBI:133518 biolink:ChemicalSubstance (E)-3-methylglutaconate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133518 GO:1903446 biolink:BiologicalProcess geraniol metabolic process The chemical reactions and pathways involving geraniol. go-plus.json geraniol metabolism http://purl.obolibrary.org/obo/GO_1903446 CHEBI:133517 biolink:ChemicalSubstance 5alpha-androstane-3alpha,17beta-diol 17-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133517 GO:0014868 biolink:BiologicalProcess cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014868 GO:1903445 biolink:BiologicalProcess protein transport from ciliary membrane to plasma membrane The directed movement of protein from ciliary membrane to plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903445 GO:1903444 biolink:BiologicalProcess negative regulation of brown fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. go-plus.json down-regulation of brown adipocyte cell differentiation|negative regulation of brown adipocyte cell differentiation|inhibition of brown adipocyte differentiation|downregulation of brown adipocyte cell differentiation|down regulation of brown adipocyte cell differentiation|down regulation of brown adipocyte differentiation|down-regulation of brown fat cell differentiation|inhibition of brown adipocyte cell differentiation|downregulation of brown adipocyte differentiation|downregulation of brown fat cell differentiation|negative regulation of brown adipocyte differentiation|down-regulation of brown adipocyte differentiation|down regulation of brown fat cell differentiation|inhibition of brown fat cell differentiation http://purl.obolibrary.org/obo/GO_1903444 CHEBI:133519 biolink:ChemicalSubstance 5alpha-androstane-3alpha,17beta-diol 17-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133519 chebi_ph7_3 GO:1903443 biolink:BiologicalProcess cellular response to lipoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903443 GO:1903442 biolink:BiologicalProcess response to lipoic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903442 GO:0048289 biolink:BiologicalProcess isotype switching to IgE isotypes The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. go-plus.json class switching to IgE isotypes|class switch recombination to IgE isotypes|isotype switch recombination to IgE isotypes http://purl.obolibrary.org/obo/GO_0048289 GO:1903452 biolink:BiologicalProcess positive regulation of G1 to G0 transition Any process that activates or increases the frequency, rate or extent of G1 to G0 transition. go-plus.json positive regulation of cell cycle quiescence|positive regulation of establishment of cell quiescence|up regulation of establishment of cell quiescence|activation of cell cycle quiescence|upregulation of G1 to G0 transition|up-regulation of stationary phase|activation of G1/G0 transition|up-regulation of G1/G0 transition|up-regulation of cell cycle quiescence|activation of stationary phase|upregulation of establishment of cell quiescence|up regulation of G1 to G0 transition|positive regulation of stationary phase|activation of G1 to G0 transition|up regulation of stationary phase|positive regulation of G1/G0 transition|upregulation of cell cycle quiescence|up regulation of G1/G0 transition|up-regulation of establishment of cell quiescence|activation of establishment of cell quiescence|up-regulation of G1 to G0 transition|upregulation of stationary phase|up regulation of cell cycle quiescence|upregulation of G1/G0 transition http://purl.obolibrary.org/obo/GO_1903452 GO:0014863 biolink:BiologicalProcess detection of inactivity The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0014863 GO:1903451 biolink:BiologicalProcess negative regulation of G1 to G0 transition Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition. go-plus.json down-regulation of cell cycle quiescence|negative regulation of cell cycle quiescence|downregulation of establishment of cell quiescence|down regulation of G1 to G0 transition|down regulation of establishment of cell quiescence|negative regulation of stationary phase|inhibition of establishment of cell quiescence|down-regulation of stationary phase|downregulation of G1 to G0 transition|down-regulation of G1/G0 transition|negative regulation of G1/G0 transition|inhibition of cell cycle quiescence|down-regulation of G1 to G0 transition|downregulation of stationary phase|down regulation of cell cycle quiescence|downregulation of G1/G0 transition|down regulation of stationary phase|downregulation of cell cycle quiescence|inhibition of G1 to G0 transition|down regulation of G1/G0 transition|negative regulation of establishment of cell quiescence|down-regulation of establishment of cell quiescence|inhibition of G1/G0 transition|inhibition of stationary phase http://purl.obolibrary.org/obo/GO_1903451 GO:0014862 biolink:BiologicalProcess regulation of skeletal muscle contraction by chemo-mechanical energy conversion Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres. go-plus.json http://purl.obolibrary.org/obo/GO_0014862 GO:0014861 biolink:BiologicalProcess regulation of skeletal muscle contraction via regulation of action potential Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes. go-plus.json regulation of skeletal muscle contraction via membrane action potential http://purl.obolibrary.org/obo/GO_0014861 CHEBI:38149 biolink:ChemicalSubstance 19-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38149 GO:1903450 biolink:BiologicalProcess regulation of G1 to G0 transition Any process that modulates the frequency, rate or extent of G1 to G0 transition. go-plus.json regulation of establishment of cell quiescence|regulation of stationary phase|regulation of cell cycle quiescence|regulation of G1/G0 transition http://purl.obolibrary.org/obo/GO_1903450 CHEBI:133510 biolink:ChemicalSubstance alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133510 chebi_ph7_3 GO:0014860 biolink:BiologicalProcess neurotransmitter secretion involved in regulation of skeletal muscle contraction The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. go-plus.json neurotransmitter secretion involved in control of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0014860 GO:0014866 biolink:BiologicalProcess skeletal myofibril assembly The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0014866 CHEBI:133511 biolink:ChemicalSubstance 3-hydroxyoctanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133511 chebi_ph7_3 GO:0014865 biolink:BiologicalProcess detection of activity The series of events in which an activity stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0014865 CHEBI:133514 biolink:ChemicalSubstance 2-hydroxyoctanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133514 chebi_ph7_3 CHEBI:133513 biolink:ChemicalSubstance 3-methylglutaconate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133513 GO:0014864 biolink:BiologicalProcess detection of muscle activity The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0014864 CHEBI:53784 biolink:ChemicalSubstance antispasmodic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_53784 GO:0048291 biolink:BiologicalProcess isotype switching to IgG isotypes The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. go-plus.json isotype switch recombination to IgG isotypes|class switching to IgG isotypes http://purl.obolibrary.org/obo/GO_0048291 CHEBI:38142 biolink:ChemicalSubstance 1,2-dihydronaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38142 chebi_ph7_3 GO:0000229 biolink:CellularComponent cytoplasmic chromosome A chromosome found in the cytoplasm. go-plus.json cytoplasmic interphase chromosome http://purl.obolibrary.org/obo/GO_0000229 goslim_generic|goslim_chembl GO:0048290 biolink:BiologicalProcess isotype switching to IgA isotypes The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus. go-plus.json class switching to IgA isotypes|isotype switch recombination to IgA isotypes http://purl.obolibrary.org/obo/GO_0048290 GO:0000228 biolink:CellularComponent nuclear chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. go-plus.json nuclear interphase chromosome http://purl.obolibrary.org/obo/GO_0000228 goslim_generic|goslim_chembl CHEBI:38141 biolink:ChemicalSubstance dihydronaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38141 GO:0000227 biolink:MolecularActivity oxaloacetate secondary active transmembrane transporter activity Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json oxaloacetate carrier activity http://purl.obolibrary.org/obo/GO_0000227 CHEBI:38147 biolink:ChemicalSubstance cardiotonic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_38147 GO:0048299 biolink:BiologicalProcess regulation of isotype switching to IgD isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes. go-plus.json regulation of class switching to IgD isotypes|regulation of class switch recombination to IgD isotypes|regulation of isotype switch recombination to IgD isotypes http://purl.obolibrary.org/obo/GO_0048299 GO:0000233 biolink:CellularComponent obsolete cytoplasmic interphase chromosome OBSOLETE. A chromosome found in the cytoplasm during interphase. go-plus.json cytoplasmic interphase chromosome http://purl.obolibrary.org/obo/GO_0000233 GO:0048298 biolink:BiologicalProcess positive regulation of isotype switching to IgA isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes. go-plus.json positive regulation of class switch recombination to IgA isotypes|stimulation of isotype switching to IgA isotypes|positive regulation of class switching to IgA isotypes|positive regulation of isotype switch recombination to IgA isotypes|up-regulation of isotype switching to IgA isotypes|upregulation of isotype switching to IgA isotypes|up regulation of isotype switching to IgA isotypes|activation of isotype switching to IgA isotypes http://purl.obolibrary.org/obo/GO_0048298 GO:0000232 biolink:CellularComponent obsolete nuclear interphase chromosome OBSOLETE. A chromosome found in the nucleus during interphase. go-plus.json nuclear interphase chromosome http://purl.obolibrary.org/obo/GO_0000232 GO:0000231 biolink:CellularComponent obsolete cytoplasmic mitotic chromosome OBSOLETE. A chromosome found in the cytoplasm during mitosis. go-plus.json cytoplasmic mitotic chromosome http://purl.obolibrary.org/obo/GO_0000231 GO:0048297 biolink:BiologicalProcess negative regulation of isotype switching to IgA isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes. go-plus.json down-regulation of isotype switching to IgA isotypes|negative regulation of isotype switch recombination to IgA isotypes|inhibition of isotype switching to IgA isotypes|negative regulation of class switching to IgA isotypes|down regulation of isotype switching to IgA isotypes|downregulation of isotype switching to IgA isotypes|negative regulation of class switch recombination to IgA isotypes http://purl.obolibrary.org/obo/GO_0048297 GO:0048296 biolink:BiologicalProcess regulation of isotype switching to IgA isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes. go-plus.json regulation of class switch recombination to IgA isotypes|regulation of isotype switch recombination to IgA isotypes|regulation of class switching to IgA isotypes http://purl.obolibrary.org/obo/GO_0048296 GO:0000230 biolink:CellularComponent obsolete nuclear mitotic chromosome OBSOLETE. A chromosome found in the nucleus during mitosis. go-plus.json nuclear mitotic chromosome http://purl.obolibrary.org/obo/GO_0000230 GO:0048295 biolink:BiologicalProcess positive regulation of isotype switching to IgE isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes. go-plus.json up regulation of isotype switching to IgE isotypes|activation of isotype switching to IgE isotypes|positive regulation of class switch recombination to IgE isotypes|stimulation of isotype switching to IgE isotypes|positive regulation of class switching to IgE isotypes|positive regulation of isotype switch recombination to IgE isotypes|up-regulation of isotype switching to IgE isotypes|upregulation of isotype switching to IgE isotypes http://purl.obolibrary.org/obo/GO_0048295 GO:0000237 biolink:BiologicalProcess leptotene The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible. Wikipedia:Leptotene|Wikipedia:Meiosis#Leptotene go-plus.json http://purl.obolibrary.org/obo/GO_0000237 gocheck_do_not_annotate CHEBI:38161 biolink:ChemicalSubstance chelator go-plus.json http://purl.obolibrary.org/obo/CHEBI_38161 GO:0048294 biolink:BiologicalProcess negative regulation of isotype switching to IgE isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes. go-plus.json down-regulation of isotype switching to IgE isotypes|negative regulation of isotype switch recombination to IgE isotypes|inhibition of isotype switching to IgE isotypes|negative regulation of class switching to IgE isotypes|down regulation of isotype switching to IgE isotypes|downregulation of isotype switching to IgE isotypes|negative regulation of class switch recombination to IgE isotypes http://purl.obolibrary.org/obo/GO_0048294 GO:0000236 biolink:BiologicalProcess mitotic prometaphase The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles. go-plus.json http://purl.obolibrary.org/obo/GO_0000236 gocheck_do_not_annotate CHEBI:38160 biolink:ChemicalSubstance 3''-deamino-3''-oxonicotianamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38160 GO:0048293 biolink:BiologicalProcess regulation of isotype switching to IgE isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. go-plus.json regulation of class switching to IgE isotypes|regulation of class switch recombination to IgE isotypes|regulation of isotype switch recombination to IgE isotypes http://purl.obolibrary.org/obo/GO_0048293 GO:0000235 biolink:CellularComponent astral microtubule Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0000235 GO:0048292 biolink:BiologicalProcess isotype switching to IgD isotypes The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus. go-plus.json isotype switch recombination to IgD isotypes|class switching to IgD isotypes http://purl.obolibrary.org/obo/GO_0048292 GO:0000234 biolink:MolecularActivity phosphoethanolamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate. RHEA:20365|KEGG_REACTION:R02037|MetaCyc:2.1.1.103-RXN|EC:2.1.1.103 go-plus.json S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity|phosphoethanolamine methyltransferase activity http://purl.obolibrary.org/obo/GO_0000234 CHEBI:87195 biolink:ChemicalSubstance dicarboximide fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87195 GO:1903459 biolink:BiologicalProcess mitotic DNA replication lagging strand elongation Any lagging strand elongation that is involved in mitotic cell cycle DNA replication. go-plus.json lagging strand elongation involved in mitotic nuclear cell cycle DNA replication|lagging strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle|lagging strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|lagging strand elongation involved in mitotic DNA replication|lagging strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|lagging strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903459 CHEBI:133526 biolink:ChemicalSubstance oxodocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133526 CHEBI:87197 biolink:ChemicalSubstance dichlorophenyl dicarboximide fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87197 GO:1903458 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903458 GO:1903457 biolink:BiologicalProcess lactate catabolic process The chemical reactions and pathways resulting in the breakdown of lactate. go-plus.json lactate degradation|lactate breakdown|lactate catabolism http://purl.obolibrary.org/obo/GO_1903457 GO:0014879 biolink:BiologicalProcess detection of electrical stimulus involved in regulation of muscle adaptation The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. go-plus.json http://purl.obolibrary.org/obo/GO_0014879 GO:1903456 biolink:BiologicalProcess positive regulation of androst-4-ene-3,17-dione biosynthetic process Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process. go-plus.json upregulation of androst-4-ene-3,17-dione formation|up-regulation of androst-4-ene-3,17-dione biosynthetic process|up-regulation of androst-4-ene-3,17-dione anabolism|up-regulation of androst-4-ene-3,17-dione biosynthesis|activation of androst-4-ene-3,17-dione anabolism|up-regulation of androst-4-ene-3,17-dione synthesis|activation of androst-4-ene-3,17-dione synthesis|positive regulation of androstenedione biosynthetic process|up-regulation of androst-4-ene-3,17-dione formation|activation of androst-4-ene-3,17-dione formation|up regulation of androstenedione biosynthetic process|upregulation of androst-4-ene-3,17-dione biosynthetic process|upregulation of androst-4-ene-3,17-dione biosynthesis|positive regulation of androst-4-ene-3,17-dione anabolism|up regulation of androst-4-ene-3,17-dione anabolism|positive regulation of androst-4-ene-3,17-dione synthesis|up regulation of androst-4-ene-3,17-dione synthesis|activation of androstenedione|upregulation of androstenedione biosynthetic process|positive regulation of androst-4-ene-3,17-dione formation|up regulation of androst-4-ene-3,17-dione biosynthetic process|up regulation of androst-4-ene-3,17-dione biosynthesis|up regulation of androst-4-ene-3,17-dione formation|positive regulation of androst-4-ene-3,17-dione biosynthesis|activation of androst-4-ene-3,17-dione biosynthesis|activation of androst-4-ene-3,17-dione biosynthetic process|upregulation of androst-4-ene-3,17-dione anabolism|upregulation of androst-4-ene-3,17-dione synthesis|up-regulation of androstenedione biosynthetic process http://purl.obolibrary.org/obo/GO_1903456 GO:1903455 biolink:BiologicalProcess negative regulation of androst-4-ene-3,17-dione biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process. go-plus.json inhibition of androstenedione|inhibition of androst-4-ene-3,17-dione formation|inhibition of androst-4-ene-3,17-dione biosynthesis|inhibition of androst-4-ene-3,17-dione biosynthetic process|negative regulation of androstenedione biosynthetic process|down-regulation of androstenedione biosynthetic process|negative regulation of androst-4-ene-3,17-dione anabolism|down-regulation of androst-4-ene-3,17-dione anabolism|downregulation of androstenedione biosynthetic process|negative regulation of androst-4-ene-3,17-dione synthesis|down-regulation of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione biosynthesis|down regulation of androst-4-ene-3,17-dione biosynthetic process|negative regulation of androst-4-ene-3,17-dione formation|down-regulation of androst-4-ene-3,17-dione formation|down regulation of androstenedione biosynthetic process|downregulation of androst-4-ene-3,17-dione anabolism|downregulation of androst-4-ene-3,17-dione biosynthetic process|downregulation of androst-4-ene-3,17-dione biosynthesis|downregulation of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione anabolism|inhibition of androst-4-ene-3,17-dione anabolism|downregulation of androst-4-ene-3,17-dione formation|down regulation of androst-4-ene-3,17-dione synthesis|down-regulation of androst-4-ene-3,17-dione biosynthetic process|down-regulation of androst-4-ene-3,17-dione biosynthesis|negative regulation of androst-4-ene-3,17-dione biosynthesis|inhibition of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione formation http://purl.obolibrary.org/obo/GO_1903455 GO:1903454 biolink:BiologicalProcess regulation of androst-4-ene-3,17-dione biosynthetic process Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process. go-plus.json regulation of androstenedione biosynthetic process|regulation of androst-4-ene-3,17-dione biosynthesis|regulation of androst-4-ene-3,17-dione anabolism|regulation of androst-4-ene-3,17-dione synthesis|regulation of androst-4-ene-3,17-dione formation http://purl.obolibrary.org/obo/GO_1903454 GO:1903453 biolink:BiologicalProcess obsolete RNA interference involved in olfactory learning OBSOLETE. Any RNA interference that is involved in olfactory learning. go-plus.json RNAi involved in olfactory learning|posttranscriptional gene silencing by siRNA involved in olfactory learning http://purl.obolibrary.org/obo/GO_1903453 GO:0014874 biolink:BiologicalProcess response to stimulus involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. go-plus.json response to stimulus involved in regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014874 GO:1903463 biolink:BiologicalProcess regulation of mitotic cell cycle DNA replication Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication. go-plus.json regulation of mitotic nuclear cell cycle DNA replication|regulation of DNA replication involved in S phase involved in mitotic cell cycle|regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|regulation of DNA replication during S phase involved in mitotic cell cycle|regulation of DNA replication involved in S-phase involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903463 GO:0014873 biolink:BiologicalProcess response to muscle activity involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation. go-plus.json response to fatigue|response to muscle activity involved in regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014873 GO:1903461 biolink:BiologicalProcess Okazaki fragment processing involved in mitotic DNA replication Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication. go-plus.json DNA replication, Okazaki fragment processing involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in mitotic nuclear cell cycle DNA replication|DNA replication, Okazaki fragment processing involved in DNA replication during S phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in DNA replication involved in S phase involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903461 GO:0014872 biolink:BiologicalProcess myoblast division The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0014872 GO:1903460 biolink:BiologicalProcess mitotic DNA replication leading strand elongation Any leading strand elongation that is involved in mitotic cell cycle DNA replication. go-plus.json leading strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle|leading strand elongation involved in mitotic nuclear cell cycle DNA replication|leading strand elongation involved in mitotic DNA replication|leading strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|leading strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|leading strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903460 CHEBI:38159 biolink:ChemicalSubstance 3-epi-3-hydroxy-2'-deoxymugineic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38159 CHEBI:133520 biolink:ChemicalSubstance N-acetyl-L-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133520 chebi_ph7_3 GO:0014871 biolink:BiologicalProcess cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0014871 GO:0014878 biolink:BiologicalProcess response to electrical stimulus involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. go-plus.json response to electrical stimulus involved in regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014878 GO:0014877 biolink:BiologicalProcess response to muscle inactivity involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation. go-plus.json http://purl.obolibrary.org/obo/GO_0014877 GO:0014876 biolink:BiologicalProcess response to injury involved in regulation of muscle adaptation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation. go-plus.json response to injury involved in regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0014876 CHEBI:133525 biolink:ChemicalSubstance N-acylphytosphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133525 chebi_ph7_3 GO:0014875 biolink:BiologicalProcess detection of muscle activity involved in regulation of muscle adaptation The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. go-plus.json detection of fatigue http://purl.obolibrary.org/obo/GO_0014875 GO:0000239 biolink:BiologicalProcess pachytene The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome. Wikipedia:Pachytene|Wikipedia:Meiosis#Pachytene go-plus.json http://purl.obolibrary.org/obo/GO_0000239 gocheck_do_not_annotate GO:0000238 biolink:BiologicalProcess zygotene The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur. Wikipedia:Meiosis#Zygotene|Wikipedia:Zygotene go-plus.json http://purl.obolibrary.org/obo/GO_0000238 gocheck_do_not_annotate CHEBI:38151 biolink:ChemicalSubstance ferrienterobactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38151 GO:0014870 biolink:BiologicalProcess response to muscle inactivity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0014870 CHEBI:38157 biolink:ChemicalSubstance iron chelator go-plus.json http://purl.obolibrary.org/obo/CHEBI_38157 CHEBI:38155 biolink:ChemicalSubstance phytosiderophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_38155 PR:000025513 biolink:Protein modified amino-acid residue An organic group that results from covalent modification or chemical alteration to the side chain or backbone atoms of an amino acid residue or derivative thereof, where such alteration maintains the integrity of the amino acid chain containing the residue. go-plus.json modified amino acid chain residue|modified protein residue http://purl.obolibrary.org/obo/PR_000025513 NCBITaxon:204428 biolink:OrganismalEntity Chlamydiae go-plus.json Chlamydaeota|Chlamydiota http://purl.obolibrary.org/obo/NCBITaxon_204428 NCBITaxon:204429 biolink:OrganismalEntity Chlamydiia go-plus.json Chlamydiae http://purl.obolibrary.org/obo/NCBITaxon_204429 PR:000001546 biolink:Protein prolactin-releasing peptide receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human PRLHR gene or a 1:1 ortholog thereof. go-plus.json PRLHR|PrRPR|Gm339|G-protein coupled receptor 10|GPR10|GR3|PrRP receptor http://purl.obolibrary.org/obo/PR_000001546 PR:000001548 biolink:Protein prostaglandin E2 receptor EP4 subtype A prostanoid receptor that is a translation product of the human PTGER4 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2. This receptor is not closely related to other prostaglandin E2 receptors. go-plus.json Ptgerep4|PGE receptor EP4 subtype|prostanoid EP4 receptor|PTGER4|PTGER2|prostaglandin E2 receptor EP4|PGE2 receptor EP4 subtype http://purl.obolibrary.org/obo/PR_000001548 PR:000001549 biolink:Protein prostanoid receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human PTGDR, PTGDR2, PTGER1 to PTGER4, PTGFR, PTGIR, or TBXA2R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds prostanoids (prostaglandins and thromboxanes). go-plus.json http://purl.obolibrary.org/obo/PR_000001549 CHEBI:77746 biolink:ChemicalSubstance human metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_77746 CHEBI:77749 biolink:ChemicalSubstance 1-palmitoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77749 chebi_ph7_3 PR:000001550 biolink:Protein proteinase-activated receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human F2R, or F2RL1 to F2RL3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds trypsin-related proteinases. The proteinase cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity. go-plus.json fam:PAR http://purl.obolibrary.org/obo/PR_000001550 PR:000001555 biolink:Protein somatostatin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human SSTR1 to SSTR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds somatostatin. go-plus.json http://purl.obolibrary.org/obo/PR_000001555 PR:000001557 biolink:Protein thyrotropin-releasing hormone receptor type 1 A thyrotropin-releasing hormone receptor that is a translation product of the human TRHR gene or a 1:1 ortholog thereof. The preferred ligand is thyrotropin-releasing hormone. go-plus.json TRH-R1|TRHR|thyroliberin receptor|TRH-R http://purl.obolibrary.org/obo/PR_000001557 CHEBI:77740 biolink:ChemicalSubstance adenosine 2'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77740 chebi_ph7_3 CHEBI:77756 biolink:ChemicalSubstance 2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77756 chebi_ph7_3 CHEBI:63114 biolink:ChemicalSubstance sphingosine-1-phosphate receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_63114 CHEBI:77755 biolink:ChemicalSubstance 10-hydroperoxy-8E-octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77755 chebi_ph7_3 CHEBI:77754 biolink:ChemicalSubstance 9-hydroperoxy-10E-octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77754 chebi_ph7_3 CHEBI:77753 biolink:ChemicalSubstance 1-palmitoyl-2-[(10E)-9-hydroperoxyoctadecenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77753 chebi_ph7_3 CHEBI:77769 biolink:ChemicalSubstance 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77769 chebi_ph7_3 CHEBI:77767 biolink:ChemicalSubstance 3,6-dichlorocatechol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77767 chebi_ph7_3 CHEBI:77766 biolink:ChemicalSubstance cytidine 2'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77766 chebi_ph7_3 CHEBI:77765 biolink:ChemicalSubstance 2,4,6-trihydroxybenzophenone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77765 chebi_ph7_3 CHEBI:77764 biolink:ChemicalSubstance daidzein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77764 chebi_ph7_3 CHEBI:157597 biolink:ChemicalSubstance N-tetracosenoyl-sphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_157597 chebi_ph7_3 UBERON:0035480 biolink:AnatomicalEntity surface of prostate The external portion of the prostate including the anterior, inferolateral, lateral and posterior surfaces. go-plus.json surface of prostate gland|prostatic surface http://purl.obolibrary.org/obo/UBERON_0035480 UBERON:0035483 biolink:AnatomicalEntity left suprarenal vein A vein that drains blood from the left adrenal gland into the left renal artery. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035483 CHEBI:63131 biolink:ChemicalSubstance EDTA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63131 CHEBI:87101 biolink:ChemicalSubstance triazole antifungal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_87101 PR:000001590 biolink:Protein kappa-type opioid receptor An opioid receptor protein that is a translation product of the human OPRK1 gene or a 1:1 ortholog thereof. The preferred ligand is dynorphin. go-plus.json kappa-opioid receptor|OPRK1|OPRK|KOR-1|K-OR-1|MSL-1 http://purl.obolibrary.org/obo/PR_000001590 CHEBI:87107 biolink:ChemicalSubstance 7-O-[(2-aminoethyl)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87107 chebi_ph7_3 CHEBI:87109 biolink:ChemicalSubstance juvenile hormone I carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87109 chebi_ph7_3 CHEBI:63137 biolink:ChemicalSubstance 4-hydroxyproline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63137 chebi_ph7_3 NCBITaxon:36329 biolink:OrganismalEntity Plasmodium falciparum 3D7 go-plus.json Plasmodium falciparum (isolate 3D7) http://purl.obolibrary.org/obo/NCBITaxon_36329 CHEBI:77771 biolink:ChemicalSubstance cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77771 chebi_ph7_3 CHEBI:77770 biolink:ChemicalSubstance 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77770 chebi_ph7_3 PR:000001596 biolink:Protein lutropin-choriogonadotropic hormone receptor A glycoprotein hormone receptor that is a translation product of the human LHCGR gene or a 1:1 ortholog thereof. The preferred ligands are lutropin (luteinizing hormone) and choriogonadotropin (choriogonadotropic hormone). go-plus.json LHR|LGR2|LHCGR|luteinizing hormone receptor|LSH-R|lutropin/choriogonadotropin receptor|LCGR|LH/CG-R|LHRHR http://purl.obolibrary.org/obo/PR_000001596 CHEBI:77787 biolink:ChemicalSubstance 1-O-palmityl-2-desoxy-2-amino-sn-glycero-3-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77787 chebi_ph7_3 CHEBI:231935 biolink:ChemicalSubstance glycerol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_231935 chebi_ph7_3 CHEBI:77786 biolink:ChemicalSubstance 1-hexadecyl-2-ammonio-2-deoxy-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77786 chebi_ph7_3 GO:0048200 biolink:BiologicalProcess Golgi transport vesicle coating The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles. go-plus.json dictyosome transport vesicle coating http://purl.obolibrary.org/obo/GO_0048200 CHEBI:63150 biolink:ChemicalSubstance D-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63150 GO:0048208 biolink:BiologicalProcess COPII vesicle coating The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat. go-plus.json COPII coating of ER-derived vesicle|COPII vesicle coat assembly|COPII vesicle coat formation http://purl.obolibrary.org/obo/GO_0048208 CHEBI:87121 biolink:ChemicalSubstance bisanhydrobacterioruberin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87121 chebi_ph7_3 CHEBI:87120 biolink:ChemicalSubstance 4-methylpent-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87120 chebi_ph7_3 GO:0048207 biolink:BiologicalProcess vesicle targeting, rough ER to cis-Golgi The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi. go-plus.json rough ER to cis-Golgi targeting|vesicle targeting, rough endoplasmic reticulum to cis-Golgi|rough endoplasmic reticulum to cis-Golgi targeting http://purl.obolibrary.org/obo/GO_0048207 GO:0048206 biolink:BiologicalProcess vesicle targeting, cis-Golgi to rough endoplasmic reticulum The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER. go-plus.json vesicle targeting, cis-Golgi to rough ER|vesicle targeting, cis-Golgi to rough endoplasmic reticulum|cis-Golgi to rough ER targeting|cis-Golgi to rough endoplasmic reticulum targeting http://purl.obolibrary.org/obo/GO_0048206 CHEBI:87123 biolink:ChemicalSubstance tulipalin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_87123 chebi_ph7_3 CHEBI:87122 biolink:ChemicalSubstance monoanhydrobacterioruberin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87122 chebi_ph7_3 GO:0048205 biolink:BiologicalProcess COPI coating of Golgi vesicle The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat. go-plus.json COPI vesicle coating|COPI coating of Golgi-derived vesicle http://purl.obolibrary.org/obo/GO_0048205 CHEBI:63151 biolink:ChemicalSubstance D-rhamnopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63151 chebi_ph7_3 GO:0048204 biolink:BiologicalProcess vesicle targeting, inter-Golgi cisterna The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another. go-plus.json inter-Golgi cisterna targeting http://purl.obolibrary.org/obo/GO_0048204 CHEBI:63158 biolink:ChemicalSubstance EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63158 CHEBI:87125 biolink:ChemicalSubstance 5-epi-valiolone 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87125 chebi_ph7_3 CHEBI:87124 biolink:ChemicalSubstance 6-tuliposide B go-plus.json http://purl.obolibrary.org/obo/CHEBI_87124 chebi_ph7_3 GO:0048203 biolink:BiologicalProcess vesicle targeting, trans-Golgi to endosome The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome. go-plus.json trans-Golgi to endosome targeting http://purl.obolibrary.org/obo/GO_0048203 CHEBI:63157 biolink:ChemicalSubstance EC 4.2.1.22 (cystathionine beta-synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63157 GO:0048202 biolink:BiologicalProcess clathrin coating of Golgi vesicle The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat. go-plus.json clathrin coating of Golgi-derived vesicle http://purl.obolibrary.org/obo/GO_0048202 CHEBI:63156 biolink:ChemicalSubstance EC 1.1.3.13 (alcohol oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63156 GO:0048201 biolink:BiologicalProcess vesicle targeting, plasma membrane to endosome The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces. go-plus.json plasma membrane to endosome targeting http://purl.obolibrary.org/obo/GO_0048201 PR:000001562 biolink:Protein vasopressin/oxytocin receptor A rhodopsin-like G-protein coupled receptor that that is a translation product of the human AVPR1A, AVPR1B, AVPR2, or OXTR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. These receptors bind vasopressin or oxytocin or related nonapeptides. go-plus.json name: vasopressin and oxytocin receptor http://purl.obolibrary.org/obo/PR_000001562 CHEBI:133598 biolink:ChemicalSubstance chlortetracycline(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133598 chebi_ph7_3 PR:000001564 biolink:Protein histamine H3 receptor A histamine receptor that is a translation product of the human HRH3 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates inhibition of gastric acid release, inhibition of neurotransmitter release, and other diverse effects. go-plus.json H3R|HH3R|H3 histamine receptor|G-protein coupled receptor 97|HRH3|GPCR97 http://purl.obolibrary.org/obo/PR_000001564 CHEBI:77791 biolink:ChemicalSubstance luteolin 7-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77791 chebi_ph7_3 PR:000001565 biolink:Protein H4 histamine receptor A histamine receptor that is a translation product of the human HRH4 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor is expressed primarily in the bone marrow and eosinophils but also in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. go-plus.json G-protein coupled receptor 105|GPRv53|H4R|HH4R|AXOR35|GPCR105|Pfi-013|HRH4|SP9144 http://purl.obolibrary.org/obo/PR_000001565 GO:0048209 biolink:BiologicalProcess regulation of vesicle targeting, to, from or within Golgi Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. go-plus.json regulation of Golgi vesicle targeting http://purl.obolibrary.org/obo/GO_0048209 CHEBI:77798 biolink:ChemicalSubstance melamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77798 chebi_ph7_3 GO:0048211 biolink:BiologicalProcess Golgi vesicle docking The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane. go-plus.json Golgi vesicle to membrane docking|dictyosome vesicle docking to target membrane|Golgi vesicle docking with target membrane|Golgi-derived vesicle docking http://purl.obolibrary.org/obo/GO_0048211 GO:0048210 biolink:BiologicalProcess Golgi vesicle fusion to target membrane The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane. go-plus.json Golgi-derived vesicle fusion to target membrane|dictyosome vesicle fusion to target membrane http://purl.obolibrary.org/obo/GO_0048210 CHEBI:63161 biolink:ChemicalSubstance glycosyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_63161 GO:0048219 biolink:BiologicalProcess inter-Golgi cisterna vesicle-mediated transport The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles. go-plus.json inter-Golgi cisterna transport http://purl.obolibrary.org/obo/GO_0048219 CHEBI:63165 biolink:ChemicalSubstance ribonucleoside monophosphate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63165 GO:0048218 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048218 CHEBI:63164 biolink:ChemicalSubstance prosolanapyrone III go-plus.json http://purl.obolibrary.org/obo/CHEBI_63164 chebi_ph7_3 GO:0048217 biolink:CellularComponent pectic matrix The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls. go-plus.json http://purl.obolibrary.org/obo/GO_0048217 CHEBI:63163 biolink:ChemicalSubstance L-cystine anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63163 GO:0048216 biolink:BiologicalProcess negative regulation of Golgi vesicle fusion to target membrane Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane. go-plus.json inhibition of Golgi vesicle fusion to target membrane|down regulation of Golgi vesicle fusion to target membrane|downregulation of Golgi vesicle fusion to target membrane|down-regulation of Golgi vesicle fusion to target membrane http://purl.obolibrary.org/obo/GO_0048216 CHEBI:87114 biolink:ChemicalSubstance antibiotic fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87114 GO:0048215 biolink:BiologicalProcess positive regulation of Golgi vesicle fusion to target membrane Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane. go-plus.json up-regulation of Golgi vesicle fusion to target membrane|upregulation of Golgi vesicle fusion to target membrane|up regulation of Golgi vesicle fusion to target membrane|activation of Golgi vesicle fusion to target membrane|stimulation of Golgi vesicle fusion to target membrane http://purl.obolibrary.org/obo/GO_0048215 CHEBI:63169 biolink:ChemicalSubstance pyranopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63169 CHEBI:87113 biolink:ChemicalSubstance antibiotic antifungal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_87113 GO:0048214 biolink:BiologicalProcess regulation of Golgi vesicle fusion to target membrane Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0048214 CHEBI:63168 biolink:ChemicalSubstance perakine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63168 chebi_ph7_3 GO:0048213 biolink:BiologicalProcess Golgi vesicle prefusion complex stabilization The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized. go-plus.json Golgi vesicle prefusion complex assembly|Golgi-derived vesicle prefusion complex stabilization|dictyosome vesicle prefusion complex stabilisation http://purl.obolibrary.org/obo/GO_0048213 CHEBI:63167 biolink:ChemicalSubstance raucaffrinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_63167 chebi_ph7_3 GO:0048212 biolink:BiologicalProcess Golgi vesicle uncoating The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse. go-plus.json Golgi vesicle coat depolymerization|dictyosome vesicle coat depolymerization|Golgi vesicle coat protein depolymerization|Golgi-derived vesicle uncoating http://purl.obolibrary.org/obo/GO_0048212 CHEBI:63166 biolink:ChemicalSubstance leukotriene D4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63166 chebi_ph7_3 CHEBI:87119 biolink:ChemicalSubstance (R)-2-hydroxy-4-methylpentanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87119 chebi_ph7_3 PR:000001579 biolink:Protein delta-type opioid receptor An opioid receptor protein that is a translation product of the human OPRD1 gene or a 1:1 ortholog thereof. The preferred ligands are enkephalins. go-plus.json OPRD1|D-OR-1|OPRD|K56|DOR-1|MSL-2|delta-opioid receptor http://purl.obolibrary.org/obo/PR_000001579 CHEBI:24367 biolink:ChemicalSubstance glycinamide ribonucleotide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_24367 CHEBI:48337 biolink:ChemicalSubstance pyrrolopyrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48337 UBERON:0001789 biolink:AnatomicalEntity outer nuclear layer of retina The layer within the retina where the photoreceptor cell bodies reside. go-plus.json outer nuclear layer|retinal outer nuclear layer|stratum nucleare externum retinae|retina, outer nuclear layer|external nuclear layer|layer of outer granules|ONL|stratum nucleare externum (retina)|neural retina outer nuclear layer|retina outer nuclear layer|retinal outer nuclear layers http://purl.obolibrary.org/obo/UBERON_0001789 UBERON:0001788 biolink:AnatomicalEntity outer limiting layer of retina The row of jucntional complexes between the plasma membranes of rod segments and the Muller glia cells; this barrier separates the layer of inner and outer segments of the rods and cones from the outer nuclear layer and forms a blood-retina barrier[MP]. go-plus.json outer limiting membrane|outer limiting membranes|retina outer limiting membrane|stratum limitans externum (retina)|external limiting membrane of retina|external limiting membrane|blood retina barrier|stratum limitans externum retinae|BRB|retina external limiting lamina|external limiting lamina of retina|outer limiting membrane of retina http://purl.obolibrary.org/obo/UBERON_0001788 CHEBI:24360 biolink:ChemicalSubstance glycerophosphoglycerols go-plus.json http://purl.obolibrary.org/obo/CHEBI_24360 CHEBI:63970 biolink:ChemicalSubstance (5Z,11Z,14Z)-8,9-dihydroxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63970 UBERON:0011112 biolink:AnatomicalEntity tibiofibular joint A joint that connects the tibia and the fibula. go-plus.json fibulatibial joint|tibiafibular joint|fibulotibial joint http://purl.obolibrary.org/obo/UBERON_0011112 UBERON:0011108 biolink:AnatomicalEntity synovial joint of pectoral girdle A synovial joint that is part of a pectoral girdle region. go-plus.json joint of shoulder girdle|pectoral girdle joint http://purl.obolibrary.org/obo/UBERON_0011108 CHEBI:63976 biolink:ChemicalSubstance 13,14-dihydro-15-keto-PGF2alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_63976 UBERON:0011107 biolink:AnatomicalEntity synovial joint of pelvic girdle A synovial joint that is part of a pelvic girdle region. go-plus.json joint of pelvic girdle|pelvic girdle joint http://purl.obolibrary.org/obo/UBERON_0011107 UBERON:0001790 biolink:AnatomicalEntity outer plexiform layer of retina The layer within the retina where the bipolar cells synapse with the photoreceptor cells[ZFA]. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells[GO]. go-plus.json retinal outer plexiform layers|OPL|external plexiform layer|stratum plexiforme externum|outer plexiform layer|retina outer plexiform layer|retinal outer plexiform layer|stratum plexiforme externum retinae|retina, outer plexiform layer http://purl.obolibrary.org/obo/UBERON_0001790 CHEBI:87947 biolink:ChemicalSubstance 9-ribosyl-trans-zeatin 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87947 chebi_ph7_3 CHEBI:63979 biolink:ChemicalSubstance 20-oxoleukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63979 CHEBI:63977 biolink:ChemicalSubstance 12S-HHTrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63977 UBERON:0001796 biolink:AnatomicalEntity aqueous humor of eyeball A thick watery refractive medium that fills the space between the lens and the cornea[WP]. go-plus.json aqueous humor|humor aquosus|aqueous humour http://purl.obolibrary.org/obo/UBERON_0001796 UBERON:0001795 biolink:AnatomicalEntity inner plexiform layer of retina Cytoarchitectural layer of the retina that is made up of a dense reticulum of fibrils formed by interlaced dendrites of retinal ganglion cells and cells of the inner nuclear layer (adapted from Wikipedia) go-plus.json retinal internal plexiform layer|retinal inner plexiform layer|retina, inner plexiform layer|stratum plexifome internum|IPL|internal plexiform layer of retina|stratum plexiforme internum retinae|retina inner plexiform layer|inner plexiform layer|stratum plexiforme internum http://purl.obolibrary.org/obo/UBERON_0001795 UBERON:0001798 biolink:AnatomicalEntity vitreous body Gelatinous mucoid tissue that is composed of vitreous humor and fills the cavity behind the crystalline lens of the eye and in front of the retina[MP,modified] go-plus.json http://purl.obolibrary.org/obo/UBERON_0001798 UBERON:0001797 biolink:AnatomicalEntity vitreous humor A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina go-plus.json humor vitreous|humor vitreus|humoral fluid|vitreous humour|whole portion of vitreous humor|ocular fluid|portion of vitreous humor|vitreous fluid|vitreous http://purl.obolibrary.org/obo/UBERON_0001797 UBERON:0001792 biolink:AnatomicalEntity ganglionic layer of retina Cytoarchitectural layer of retina that contains somata of retinal ganglion cells, bounded by the stratum opticum and the inner plexiform layer go-plus.json retina, ganglion cell layer|retinal ganglion layer|ganglionic cell layer of retina|stratum ganglionicum retinae|retina ganglion layer|stratum ganglionicum (retina)|GCL layer|retina ganglion cell layer|RGC layer|ganglion cell layer|retinal ganglion cell layer http://purl.obolibrary.org/obo/UBERON_0001792 UBERON:0001791 biolink:AnatomicalEntity inner nuclear layer of retina Cytoarchitectural layer of retina containing closely packed cell bodies, the majority of which are bipolar cells (adapted from Wikipedia). go-plus.json stratum nucleare internum retinae|INL|inner nuclear layer|neural retina inner nuclear layer|retina inner nuclear layer|stratum nucleare internum|retinal inner nuclear layer|layer of inner granules|intermediate cell layer|retina, inner nuclear layer http://purl.obolibrary.org/obo/UBERON_0001791 UBERON:0001794 biolink:AnatomicalEntity inner limiting layer of retina The row of fused Muller cell processes and astrocytes that separates the retinal nerve fiber layer from the vitreous[MP]. go-plus.json internal limiting membrane of retina|inner limiting membranes|inner limiting membrane of retina|stratum limitans internum retinae|inner limiting membrane|ILM|retina internal limiting lamina|internal limiting lamina of retina|retina inner limiting membrane http://purl.obolibrary.org/obo/UBERON_0001794 UBERON:0001793 biolink:AnatomicalEntity nerve fiber layer of retina layer of the retina formed by expansion of the fibers of the optic nerve go-plus.json layer of nerve fibres of retina|stratum neurofibrarum (retina)|optic fiber layer|stratum neurofibrum retinae|stratum opticum of retina|optic fiber layer|neural retina nerve fibre layer|optic fiber layers|retina nerve fiber layer|stratum neurofibrarum retinae|nerve fiber layer|layer of nerve fibers of retina http://purl.obolibrary.org/obo/UBERON_0001793 CHEBI:73301 biolink:ChemicalSubstance tirucallane go-plus.json http://purl.obolibrary.org/obo/CHEBI_73301 chebi_ph7_3 UBERON:0001778 biolink:AnatomicalEntity ciliary epithelium A double layer covering the ciliary body that produces aqueous humor. go-plus.json epithelium of ciliary body|ciliary body epithelium|ocular ciliary epithelium http://purl.obolibrary.org/obo/UBERON_0001778 UBERON:0001777 biolink:AnatomicalEntity substantia propria of cornea the lamellated connective tissue of the cornea between the Bowman and Descemet membranes go-plus.json substantia propria|corneal stroma|substantia propria corneae|stroma of cornea http://purl.obolibrary.org/obo/UBERON_0001777 dc:description biolink:OntologyClass description go-plus.json http://purl.org/dc/elements/1.1/description UBERON:0001779 biolink:AnatomicalEntity iris stroma The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae. go-plus.json stroma of iris|iridial stroma http://purl.obolibrary.org/obo/UBERON_0001779 CHEBI:73309 biolink:ChemicalSubstance aromatic 2-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73309 chebi_ph7_3 CHEBI:63983 biolink:ChemicalSubstance eoxin A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63983 CHEBI:63982 biolink:ChemicalSubstance Delta(6)-trans-12-epi-leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63982 CHEBI:24373 biolink:ChemicalSubstance glycine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24373 CHEBI:63981 biolink:ChemicalSubstance 6-trans-leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63981 CHEBI:24372 biolink:ChemicalSubstance glycine cholesterol esters go-plus.json http://purl.obolibrary.org/obo/CHEBI_24372 CHEBI:63989 biolink:ChemicalSubstance 15(R)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63989 UBERON:0001785 biolink:AnatomicalEntity cranial nerve Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. go-plus.json cranial neural tree organ|nervus cranialis|cranial nerves http://purl.obolibrary.org/obo/UBERON_0001785 UBERON:0001787 biolink:AnatomicalEntity photoreceptor layer of retina The layer within the retina where the photoreceptor cell receptor segments reside. go-plus.json layer of rods and cones|retinal photoreceptor layers|retina photoreceptor layer|stratum segmentorum externorum et internorum retinae|stratum segmentorum externorum et internorum (retina)|retinal photoreceptor layer http://purl.obolibrary.org/obo/UBERON_0001787 UBERON:0001781 biolink:AnatomicalEntity layer of retina Any of the layers that make up the retina[MP]. go-plus.json retinal layer|retinal neuronal layer|retina neuronal layer|retina layer http://purl.obolibrary.org/obo/UBERON_0001781 UBERON:0001780 biolink:AnatomicalEntity spinal nerve the any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified] go-plus.json nerve of backbone|nerve of vertebral column|spinal nerves|nerve of spinal column|backbone nerve|spinal column nerve|vertebral column nerve|nerve of spine|spine nerve|nervi spinales|spinal nerve tree http://purl.obolibrary.org/obo/UBERON_0001780 UBERON:0001782 biolink:AnatomicalEntity pigmented layer of retina A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells[WP]. go-plus.json RPE|stratum pigmentosum (retina)|pigment epithelium of retina|PRE|epithelium, retinal pigment|outer pigmented layer of retina|stratum pigmentosa retinae|pigmented epithelium|p. pigmentosa retinae|pigmented retina epithelium|stratum pigmentosum retinae|pigmented retinal epithelium|retinal pigmented epithelium|pigmented retina|retinal pigment epithelium|retinal pigment layer http://purl.obolibrary.org/obo/UBERON_0001782 CHEBI:24346 biolink:ChemicalSubstance phosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24346 CHEBI:48313 biolink:ChemicalSubstance triphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48313 CHEBI:48315 biolink:ChemicalSubstance triphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48315 CHEBI:73315 biolink:ChemicalSubstance 1-alkylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73315 chebi_ph7_3 CHEBI:24344 biolink:ChemicalSubstance 2-phosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24344 CHEBI:48314 biolink:ChemicalSubstance triphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48314 UBERON:0001766 biolink:AnatomicalEntity anterior chamber of eyeball the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens go-plus.json camera anterior bulbi oculi|eye anterior chamber|anterior chamber|camera anterior|anterior chamber of eye|camera oculi anterior|camera anterior bulbi http://purl.obolibrary.org/obo/UBERON_0001766 CHEBI:48316 biolink:ChemicalSubstance triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48316 CHEBI:73316 biolink:ChemicalSubstance 2'-deoxyribonucleoside 5'-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73316 chebi_ph7_3 UBERON:0001769 biolink:AnatomicalEntity iris the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye go-plus.json irides|anterior uvea|irises http://purl.obolibrary.org/obo/UBERON_0001769 UBERON:0001768 biolink:AnatomicalEntity uvea the pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]. go-plus.json uveal tract|tunica vasculosa of eyeball|tunica vasculosa bulbi|uvea|pars iridica retinae|vascular layer of eyeball|tunica vasculatis oculi http://purl.obolibrary.org/obo/UBERON_0001768 CHEBI:48318 biolink:ChemicalSubstance fragrance go-plus.json http://purl.obolibrary.org/obo/CHEBI_48318 CHEBI:24347 biolink:ChemicalSubstance glycerates go-plus.json http://purl.obolibrary.org/obo/CHEBI_24347 UBERON:0035102 biolink:AnatomicalEntity transverse process of caudal vertebra A transverse process that is part of a caudal vertebra go-plus.json http://purl.obolibrary.org/obo/UBERON_0035102 CHEBI:63994 biolink:ChemicalSubstance 16-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63994 CHEBI:63993 biolink:ChemicalSubstance 13,14-dihydro-15-oxolipoxin A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63993 CHEBI:63992 biolink:ChemicalSubstance 15-oxolipoxin A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63992 CHEBI:48310 biolink:ChemicalSubstance apiitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48310 chebi_ph7_3 CHEBI:63998 biolink:ChemicalSubstance 19-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63998 CHEBI:63995 biolink:ChemicalSubstance 17-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63995 UBERON:0001774 biolink:AnatomicalEntity skeletal muscle of trunk A skeletal muscle organ that is part of the trunk region. go-plus.json torso muscle organ|trunk muscle organ|muscle organ of trunk|body musculature|muscle organ of torso|trunk muscle|muscle of trunk|trunk musculature http://purl.obolibrary.org/obo/UBERON_0001774 UBERON:0001773 biolink:AnatomicalEntity sclera Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]. go-plus.json scleral capsule http://purl.obolibrary.org/obo/UBERON_0001773 UBERON:0001776 biolink:AnatomicalEntity optic choroid vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. go-plus.json choroidea|eye choroid|optic choroid|chorioid|choroid|choroidea|posterior uvea|choroid coat http://purl.obolibrary.org/obo/UBERON_0001776 UBERON:0001775 biolink:AnatomicalEntity ciliary body the thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes go-plus.json ciliary bodies|corpus ciliare|ocular ciliary body|anterior uvea http://purl.obolibrary.org/obo/UBERON_0001775 UBERON:0001772 biolink:AnatomicalEntity corneal epithelium the smooth stratified squamous epithelium that covers the outer surface of the cornea go-plus.json epithelial tissue of cornea|epithelium of cornea|anterior endothelium of cornea|epithelium anterius (cornea)|cornea epithelial tissue|epithelium anterius corneae|endothelium camerae anterioris bulbi|external epithelium of cornea|epithelium corneæ anterior layer|anterior corneal epithelium|endothelium corneale|e. anterius corneae|cornea epithelium|epithelium posterius corneae|endothelium anterius corneae http://purl.obolibrary.org/obo/UBERON_0001772 CHEBI:73311 biolink:ChemicalSubstance adenosine receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_73311 UBERON:0001759 biolink:AnatomicalEntity vagus nerve Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart). go-plus.json nerve X|vagus X nerve|vagus|vagus nerve tree|vagus nerve or its root|cranial nerve X|nervus vagus [x]|tenth cranial nerve|CN-X|nervus vagus|vagal nerve|pneuomgastric nerve|10n|vagus nerve [X] http://purl.obolibrary.org/obo/UBERON_0001759 CHEBI:24356 biolink:ChemicalSubstance glycerone phosphates go-plus.json http://purl.obolibrary.org/obo/CHEBI_24356 CHEBI:73325 biolink:ChemicalSubstance 1-(alk-1-enyl)-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73325 chebi_ph7_3 CHEBI:48306 biolink:ChemicalSubstance 2-aminobut-2-enoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_48306 chebi_ph7_3 UBERON:0001756 biolink:AnatomicalEntity middle ear The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]. go-plus.json auris media http://purl.obolibrary.org/obo/UBERON_0001756 CHEBI:48305 biolink:ChemicalSubstance 2-aminobut-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48305 CHEBI:73327 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73327 chebi_ph7_3 UBERON:0001758 biolink:AnatomicalEntity periodontium The tissues that invest or help to invest and support the teeth, including the periodontal ligament, gingivae, cementum, and alveolar and supporting bone[BTO]. go-plus.json tooth supporting structure|paradentium|periodontal ligament|periodontal membrane http://purl.obolibrary.org/obo/UBERON_0001758 CHEBI:24358 biolink:ChemicalSubstance glycerone derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24358 UBERON:0001757 biolink:AnatomicalEntity pinna The part of the ear that projects from the head, connecting to the external acoustic meatus. go-plus.json auricle of ear|auricle of external ear|auricula (auris externa)|pinnae|auricula|auricle|pinna of ear http://purl.obolibrary.org/obo/UBERON_0001757 CHEBI:48307 biolink:ChemicalSubstance L-apiitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48307 chebi_ph7_3 CHEBI:87950 biolink:ChemicalSubstance 9-ribosyl-trans-zeatin 5'-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87950 chebi_ph7_3 CHEBI:24353 biolink:ChemicalSubstance glycerol ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_24353 CHEBI:48300 biolink:ChemicalSubstance D-threitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48300 chebi_ph7_3 CHEBI:87953 biolink:ChemicalSubstance 9-ribosyl-trans-zeatin 5'-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87953 chebi_ph7_3 CHEBI:38999 biolink:ChemicalSubstance GABA-gated chloride channel antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_38999 UBERON:0001763 biolink:AnatomicalEntity odontogenic papilla A condensation of odontoblasts that forms the part of a tooth germ that gives rise to dentin and pulp in the mature tooth. It lies below a cellular aggregation known as the enamel organ. go-plus.json dentinal papilla|dental papilla|pharyngeal tooth mesenchyme|tooth mesenchyme|dermal papilla|papilla dentis|odontogenic condensation http://purl.obolibrary.org/obo/UBERON_0001763 CHEBI:48309 biolink:ChemicalSubstance N-formyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48309 UBERON:0001765 biolink:AnatomicalEntity mammary duct Epithelial tube that transports milk[GO]. go-plus.json lactiferous tubule|galactophorous tubule|lactiferous duct|mammary gland duct|galactophorous duct|ductus lactiferi|lactiferous gland duct|mammilary duct http://purl.obolibrary.org/obo/UBERON_0001765 CHEBI:73320 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73320 chebi_ph7_3 CHEBI:73322 biolink:ChemicalSubstance 1-(alk-1-enyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73322 chebi_ph7_3 CHEBI:73335 biolink:ChemicalSubstance ultraviolet filter go-plus.json http://purl.obolibrary.org/obo/CHEBI_73335 CHEBI:24323 biolink:ChemicalSubstance glutamyl-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24323 CHEBI:73336 biolink:ChemicalSubstance vulnerary go-plus.json http://purl.obolibrary.org/obo/CHEBI_73336 CHEBI:24321 biolink:ChemicalSubstance glutamo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24321 CHEBI:24326 biolink:ChemicalSubstance glutaramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24326 CHEBI:24320 biolink:ChemicalSubstance glutaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24320 UBERON:0011159 biolink:AnatomicalEntity primary subdivision of cranial skeletal system go-plus.json http://purl.obolibrary.org/obo/UBERON_0011159 UBERON:0011158 biolink:AnatomicalEntity primary subdivision of skull The skull can be divided into two: the neurocranium and the facial skeleton go-plus.json skull subdivision|subdivision of skull http://purl.obolibrary.org/obo/UBERON_0011158 UBERON:0011156 biolink:AnatomicalEntity facial skeleton Subdivision of skull that consists of the facial bones. go-plus.json viscerocranium|facial skeleton|facial bone|ossa faciei|ossa facialia http://purl.obolibrary.org/obo/UBERON_0011156 CHEBI:24329 biolink:ChemicalSubstance glutarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24329 CHEBI:73333 biolink:ChemicalSubstance scabicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_73333 CHEBI:73332 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73332 chebi_ph7_3 CHEBI:73346 biolink:ChemicalSubstance trans-coumaryl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73346 chebi_ph7_3 CHEBI:24335 biolink:ChemicalSubstance glutathione conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24335 CHEBI:24333 biolink:ChemicalSubstance glutaryl-CoAs go-plus.json http://purl.obolibrary.org/obo/CHEBI_24333 CHEBI:24337 biolink:ChemicalSubstance glutathione derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24337 UBERON:0011143 biolink:AnatomicalEntity upper urinary tract Subdivision of urinary system which consists of the kidney and the ureters. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011143 UBERON:0011142 biolink:AnatomicalEntity axial ossicle Ossicle that is part of the axial skeleton. go-plus.json ossicle of postcranial-axial skeleton|vertebral ossicle|ossicle of axial skeleton http://purl.obolibrary.org/obo/UBERON_0011142 UBERON:0011141 biolink:AnatomicalEntity appendicular ossicle Ossicle that is part of the appendicular skeleton. go-plus.json ossicle of appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0011141 UBERON:0011148 biolink:AnatomicalEntity submucosal gland Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011148 CL:1001611 biolink:Cell cerebellar neuron Neuron of the cerebellum. go-plus.json cerebellum neuron http://purl.obolibrary.org/obo/CL_1001611 CL:1001610 biolink:Cell bone marrow hematopoietic cell Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. go-plus.json bone marrow poietic cells|bone marrow hematopoietic cells http://purl.obolibrary.org/obo/CL_1001610 CHEBI:38976 biolink:ChemicalSubstance alkylbenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38976 CHEBI:38975 biolink:ChemicalSubstance methylbenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38975 UBERON:0011139 biolink:AnatomicalEntity synovial limb joint Any synovial joint that is part of a (free) limb. go-plus.json synovial joint of free limb segment http://purl.obolibrary.org/obo/UBERON_0011139 UBERON:0011138 biolink:AnatomicalEntity postcranial axial skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. go-plus.json post-cranial axial skeletal system|axial skeletal system http://purl.obolibrary.org/obo/UBERON_0011138 PR:000001753 biolink:Protein transcription factor NF-kappa-B subunit A protein with a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region. go-plus.json transcription factor NF-kappa-B http://purl.obolibrary.org/obo/PR_000001753 PO:0025606 biolink:OntologyClass native plant cell A plant cell (PO:0009002) that is either part of a multicellular whole plant (PO:0000003) 'in vivo' or a unicellular organism 'in natura' (i.e. part of a natural environment). go-plus.json http://purl.obolibrary.org/obo/PO_0025606 CHEBI:73343 biolink:ChemicalSubstance trans-anol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73343 chebi_ph7_3 CHEBI:24302 biolink:ChemicalSubstance glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24302 CHEBI:24301 biolink:ChemicalSubstance glucuronolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24301 CHEBI:73359 biolink:ChemicalSubstance alpha-CH2-containing aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_73359 chebi_ph7_3 UBERON:0011133 biolink:AnatomicalEntity intermetatarsal joint A joint that connects two adjacent metatarsals go-plus.json http://purl.obolibrary.org/obo/UBERON_0011133 UBERON:0011132 biolink:AnatomicalEntity intercarpal joint A skeletal joint that connects two carpal bones. go-plus.json intercarpal|intercarpal articulation|carpal joint|midcarpal articulation http://purl.obolibrary.org/obo/UBERON_0011132 UBERON:0011131 biolink:AnatomicalEntity intermetacarpal joint A skeletal joint that connects two adjacent metacarpals[FMA,modified]. go-plus.json intermetacarpal|intermetacarpal articulation http://purl.obolibrary.org/obo/UBERON_0011131 UBERON:0011137 biolink:AnatomicalEntity axial skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011137 NCBITaxon:85512 biolink:OrganismalEntity Dicondylia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_85512 UBERON:0011134 biolink:AnatomicalEntity nonsynovial joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. go-plus.json solid joint http://purl.obolibrary.org/obo/UBERON_0011134 CHEBI:38941 biolink:ChemicalSubstance schistosomicide drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_38941 CHEBI:24309 biolink:ChemicalSubstance glutaconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24309 CHEBI:24313 biolink:ChemicalSubstance glutamic semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_24313 CHEBI:24311 biolink:ChemicalSubstance glutaconyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_24311 CHEBI:24317 biolink:ChemicalSubstance L-glutamine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24317 UBERON:0001799 biolink:AnatomicalEntity vitreous chamber of eyeball The chamber in the eyeball enclosing the vitreous humor, bounded anteriorly by the lens and ciliary body and posteriorly by the posterior wall of the eyeball[BTO,modified]. go-plus.json vitreous chamber|camera vitrea bulbi|camera vitrea|postremal chamber of eyeball|postremal chamber|camera postrema|camera postrema bulbi oculi http://purl.obolibrary.org/obo/UBERON_0001799 CHEBI:24315 biolink:ChemicalSubstance glutamic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24315 CHEBI:87990 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_87990 CHEBI:87992 biolink:ChemicalSubstance beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_87992 UBERON:0011120 biolink:AnatomicalEntity laryngeal joint A skeletal joint that connects a laryngeal cartilage. go-plus.json laryngeal articulation|joint of larynx http://purl.obolibrary.org/obo/UBERON_0011120 CHEBI:87994 biolink:ChemicalSubstance alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)-[alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_87994 CHEBI:87996 biolink:ChemicalSubstance 3-(m-hydroxyphenyl)propanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87996 UBERON:0011119 biolink:AnatomicalEntity carpometacarpal joint The carpometacarpal joints (CMC) are joints in the wrist that articulates the distal row of carpal bones and the proximal bases of the metacarpal bones. go-plus.json articulationes carpometacarpeæ|carpometacarpal articulation|CMJ|carpometacarpal http://purl.obolibrary.org/obo/UBERON_0011119 UBERON:0011118 biolink:AnatomicalEntity tarsometatarsal joint The tarsometatarsal articulations are arthrodial joints in the pes. go-plus.json tarso-metatarsal join|tarsometatarsal articulation|cuboideometatarsal|tarsometatarsal|Lisfranc joint|articulationes tarsometatarsales http://purl.obolibrary.org/obo/UBERON_0011118 CHEBI:87997 biolink:ChemicalSubstance 3-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87997 CHEBI:38958 biolink:ChemicalSubstance indole alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38958 CHEBI:38956 biolink:ChemicalSubstance ectoparasiticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38956 CHEBI:73360 biolink:ChemicalSubstance EC 3.4.11.18 (methionyl aminopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73360 CHEBI:24319 biolink:ChemicalSubstance EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_24319 CHEBI:73361 biolink:ChemicalSubstance methionine aminopeptidase 2 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73361 CHEBI:24318 biolink:ChemicalSubstance glutamine family amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24318 UBERON:0001705 biolink:AnatomicalEntity nail A horn-like keratin structure covering the dorsal aspect of the terminal phalanges of fingers and toes[WP]. go-plus.json claw|talon|nail/claw http://purl.obolibrary.org/obo/UBERON_0001705 GO:0000442 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000442 GO:0097354 biolink:BiologicalProcess prenylation The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added. go-plus.json http://purl.obolibrary.org/obo/GO_0097354 GO:0000441 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000441 GO:0097353 biolink:BiologicalProcess centrolateral pattern formation The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment. go-plus.json mediolateral pattern formation http://purl.obolibrary.org/obo/GO_0097353 GO:0000440 biolink:CellularComponent core TFIIH complex portion of NEF3 complex The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3). go-plus.json SSL2-core TFIIH complex portion of NEF3 complex http://purl.obolibrary.org/obo/GO_0000440 UBERON:0001707 biolink:AnatomicalEntity nasal cavity An anatomical cavity that is part of the olfactory apparatus. This includes the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present. go-plus.json cavum nasi|cavity of nose|cavity of olfactory apparatus|nasal conduit space|cavitas nasi|olfactory chamber cavity|nasal canal|olfactory chamber|cavitas nasalis|olfactory cavity|olfactory pit|nasal fossa|nasal pit http://purl.obolibrary.org/obo/UBERON_0001707 GO:0097356 biolink:CellularComponent perinucleolar compartment The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC. go-plus.json perinucleolar region http://purl.obolibrary.org/obo/GO_0097356 GO:0097355 biolink:BiologicalProcess protein localization to heterochromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin. go-plus.json protein localisation to heterochromatin http://purl.obolibrary.org/obo/GO_0097355 GO:0000446 biolink:CellularComponent nucleoplasmic THO complex The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0000446 UBERON:0001701 biolink:AnatomicalEntity glossopharyngeal ganglion The group of neuron cell bodies associated with the ninth cranial nerve. go-plus.json petrosal ganglion|gIX|ganglion of glossopharyngeal nerve|glossopharyngeal IX ganglion|ganglion of glosspharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0001701 GO:0097350 biolink:BiologicalProcess neutrophil clearance The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms. go-plus.json http://purl.obolibrary.org/obo/GO_0097350 UBERON:0001700 biolink:AnatomicalEntity geniculate ganglion the group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve) go-plus.json ganglion geniculi|gVII|facial VII ganglion|ganglion geniculi nervi facialis|geniculate|internal genu|facial ganglion|genicular ganglion|geniculate ganglion|ganglion genicularum http://purl.obolibrary.org/obo/UBERON_0001700 GO:0000445 biolink:CellularComponent THO complex part of transcription export complex The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits. go-plus.json THO complex part of TREX complex http://purl.obolibrary.org/obo/GO_0000445 GO:0097352 biolink:BiologicalProcess autophagosome maturation Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling. go-plus.json autophagic vacuole fusion|autophagic vacuole maturation|autophagosome fusion http://purl.obolibrary.org/obo/GO_0097352 UBERON:0001703 biolink:AnatomicalEntity neurocranium Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof. go-plus.json brain case|brain pan|brain box|braincase http://purl.obolibrary.org/obo/UBERON_0001703 GO:0000444 biolink:CellularComponent MIS12/MIND type complex A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1. go-plus.json Mis12 complex http://purl.obolibrary.org/obo/GO_0000444 GO:0097351 biolink:MolecularActivity toxin sequestering activity Binding to a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other. go-plus.json toxin-antitoxin pair type II binding|toxin-antitoxin pair type I binding http://purl.obolibrary.org/obo/GO_0097351 GO:0000443 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000443 UBERON:0001709 biolink:AnatomicalEntity upper jaw region Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. go-plus.json dorsal pharyngeal arch 1|maxillary part of mouth|upper pharyngeal jaws|palatoquadrate arch|maxillary part of mouth proper|dorsal mandibular arch|alveolodental arch of bimaxilla http://purl.obolibrary.org/obo/UBERON_0001709 UBERON:0001708 biolink:AnatomicalEntity jaw skeleton Subdivision of skeleton which includes upper and lower jaw skeletons. go-plus.json jaws|pharyngeal arch 1 skeleton|visceral arch 1|anterior splanchnocranium|mandibular arch|mandibular arch skeleton|jaw|jaw cartilage|oral jaw skeleton http://purl.obolibrary.org/obo/UBERON_0001708 GO:0000449 biolink:BiologicalProcess endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000449 GO:0000448 biolink:BiologicalProcess cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json cleavage at C2|cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA) http://purl.obolibrary.org/obo/GO_0000448 UBERON:0001710 biolink:AnatomicalEntity lower jaw region Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. go-plus.json mandibular part of mouth|mandibular series|lower part of mouth http://purl.obolibrary.org/obo/UBERON_0001710 GO:0000447 biolink:BiologicalProcess endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json endonucleolytic cleavage at A2 http://purl.obolibrary.org/obo/GO_0000447 GO:0097358 biolink:MolecularActivity D-leucyl-tRNA(Leu) deacylase activity Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu). go-plus.json http://purl.obolibrary.org/obo/GO_0097358 GO:0097357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097357 GO:0097359 biolink:BiologicalProcess UDP-glucosylation The covalent attachment of a UDP-glucose residue to a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0097359 GO:0000453 biolink:BiologicalProcess enzyme-directed rRNA 2'-O-methylation The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000453 GO:0097365 biolink:MolecularActivity stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097365 GO:0097364 biolink:MolecularActivity stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential. go-plus.json http://purl.obolibrary.org/obo/GO_0097364 GO:0000452 biolink:BiologicalProcess snoRNA guided rRNA 2'-O-methylation The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation. go-plus.json snoRNA guided rRNA 2'-O-ribose methylation http://purl.obolibrary.org/obo/GO_0000452 GO:0097367 biolink:MolecularActivity carbohydrate derivative binding Binding to a carbohydrate derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0097367 goslim_mouse|goslim_agr GO:0000451 biolink:BiologicalProcess rRNA 2'-O-methylation The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0000451 GO:0000450 biolink:BiologicalProcess cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA) Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species. go-plus.json http://purl.obolibrary.org/obo/GO_0000450 GO:0097366 biolink:BiologicalProcess response to bronchodilator Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes. go-plus.json response to bronchodilator agent|response to broncholytic agent http://purl.obolibrary.org/obo/GO_0097366 gocheck_do_not_manually_annotate GO:0097361 biolink:CellularComponent CIA complex The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity. go-plus.json cytosolic iron-sulfur protein assembly complex http://purl.obolibrary.org/obo/GO_0097361 GO:0000457 biolink:BiologicalProcess endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000457 GO:0097360 biolink:BiologicalProcess chorionic trophoblast cell proliferation The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population. go-plus.json http://purl.obolibrary.org/obo/GO_0097360 GO:0000456 biolink:BiologicalProcess obsolete dimethylation involved in SSU-rRNA maturation OBSOLETE. Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0000456 GO:0097363 biolink:MolecularActivity protein O-GlcNAc transferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine. Reactome:R-HSA-9687828|EC:2.4.1.255 go-plus.json UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase|O-linked N-acetylglucosaminyltransferase|O-GlcNAc transferase|OGTase http://purl.obolibrary.org/obo/GO_0097363 GO:0000455 biolink:BiologicalProcess enzyme-directed rRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000455 GO:0097362 biolink:CellularComponent MCM8-MCM9 complex A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links. go-plus.json http://purl.obolibrary.org/obo/GO_0097362 GO:0000454 biolink:BiologicalProcess snoRNA guided rRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation. go-plus.json http://purl.obolibrary.org/obo/GO_0000454 CHEBI:63902 biolink:ChemicalSubstance (+)-thujan-3-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63902 chebi_ph7_3 CHEBI:63900 biolink:ChemicalSubstance 3,16-dihydroxyhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63900 CHEBI:63906 biolink:ChemicalSubstance cholest-5-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_63906 chebi_ph7_3 GO:0000459 biolink:BiologicalProcess exonucleolytic trimming involved in rRNA processing Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule. go-plus.json exonucleolytic trimming during rRNA processing http://purl.obolibrary.org/obo/GO_0000459 CHEBI:63904 biolink:ChemicalSubstance 3,16-dihydroxyhexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63904 chebi_ph7_3 GO:0000458 biolink:BiologicalProcess endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000458 GO:0097369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097369 GO:0097368 biolink:BiologicalProcess establishment of Sertoli cell barrier Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions. go-plus.json establishment of SCB|establishment of BTB|establishment of blood-testis barrier http://purl.obolibrary.org/obo/GO_0097368 GO:0097332 biolink:BiologicalProcess response to antipsychotic drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. go-plus.json http://purl.obolibrary.org/obo/GO_0097332 GO:0000420 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000420 GO:0097331 biolink:BiologicalProcess response to cytarabine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097331 GO:0097334 biolink:BiologicalProcess response to perphenazine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. go-plus.json http://purl.obolibrary.org/obo/GO_0097334 GO:0097333 biolink:BiologicalProcess response to olanzapine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097333 GO:0000424 biolink:BiologicalProcess micromitophagy Degradation of a mitochondrion by lysosomal microautophagy. go-plus.json http://purl.obolibrary.org/obo/GO_0000424 GO:0000423 biolink:BiologicalProcess mitophagy The selective autophagy process in which a mitochondrion is degraded by macroautophagy. go-plus.json macromitophagy http://purl.obolibrary.org/obo/GO_0000423 GO:0000422 biolink:BiologicalProcess autophagy of mitochondrion The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions. Wikipedia:Autophagy_(cellular)#Selective_autophagy|Wikipedia:Mitophagy go-plus.json mitochondrion autophagy|mitophagy http://purl.obolibrary.org/obo/GO_0000422 GO:0097330 biolink:BiologicalProcess response to 5-fluoro-2'-deoxyuridine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. go-plus.json http://purl.obolibrary.org/obo/GO_0097330 CL:1001609 biolink:Cell muscle fibroblast Fibroblast from muscle organ. go-plus.json http://purl.obolibrary.org/obo/CL_1001609 GO:0000421 biolink:CellularComponent autophagosome membrane The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered. go-plus.json autophagic vacuole membrane http://purl.obolibrary.org/obo/GO_0000421 CL:1001603 biolink:Cell lung macrophage Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. go-plus.json lung macrophages http://purl.obolibrary.org/obo/CL_1001603 CL:1001602 biolink:Cell cerebral cortex endothelial cell Endothelial cells forming the walls of the capillaries within the cerebral cortex. go-plus.json endothelial cells of cerebral cortex|cerebral cortex endothelial cells http://purl.obolibrary.org/obo/CL_1001602 CHEBI:48396 biolink:ChemicalSubstance 7(1)-hydroxychlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_48396 CL:1001601 biolink:Cell adrenal gland glandular cell Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens. go-plus.json suprarenal gland glandular cell|adrenal glandular cell|adrenal gland glandular cells http://purl.obolibrary.org/obo/CL_1001601 CHEBI:48399 biolink:ChemicalSubstance 13(2)-carboxypyropheophorbide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_48399 CHEBI:48398 biolink:ChemicalSubstance pyropheophorbide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_48398 CHEBI:63912 biolink:ChemicalSubstance 19-hydroxyprostaglandin H2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63912 GO:0000428 biolink:CellularComponent DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0000428 GO:0097339 biolink:BiologicalProcess glycolate transmembrane transport The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid). go-plus.json glycolate membrane transport http://purl.obolibrary.org/obo/GO_0097339 GO:0000427 biolink:CellularComponent plastid-encoded plastid RNA polymerase complex An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition. go-plus.json http://purl.obolibrary.org/obo/GO_0000427 GO:0000426 biolink:BiologicalProcess micropexophagy Degradation of a peroxisome by lysosomal microautophagy. go-plus.json http://purl.obolibrary.org/obo/GO_0000426 GO:0000425 biolink:BiologicalProcess pexophagy The selective autophagy process in which a peroxisome is degraded by macroautophagy. go-plus.json macropexophagy http://purl.obolibrary.org/obo/GO_0000425 GO:0097336 biolink:BiologicalProcess response to risperidone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097336 GO:0097335 biolink:BiologicalProcess response to quetiapine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097335 GO:0097338 biolink:BiologicalProcess response to clozapine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097338 GO:0000429 biolink:BiologicalProcess carbon catabolite regulation of transcription from RNA polymerase II promoter A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. go-plus.json regulation of transcription from RNA polymerase II promoter by carbon catabolites http://purl.obolibrary.org/obo/GO_0000429 GO:0097337 biolink:BiologicalProcess response to ziprasidone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms. go-plus.json http://purl.obolibrary.org/obo/GO_0097337 GO:0097343 biolink:BiologicalProcess ripoptosome assembly The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. go-plus.json http://purl.obolibrary.org/obo/GO_0097343 GO:0000431 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter by galactose Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0000431 GO:0097342 biolink:CellularComponent ripoptosome A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. go-plus.json Tnfr1-CII|TNFR1 complex II|necrosome http://purl.obolibrary.org/obo/GO_0097342 GO:0000430 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter by glucose Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0000430 GO:0097345 biolink:BiologicalProcess mitochondrial outer membrane permeabilization The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. go-plus.json mitochondrial outer membrane permeabilization|mitochondrion outer membrane permeabilization|mitochondrial outer membrane permeabilization during apoptotic cell death|MOMP http://purl.obolibrary.org/obo/GO_0097345 GO:0097344 biolink:CellularComponent Rix1 complex A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes. go-plus.json IPI complex http://purl.obolibrary.org/obo/GO_0097344 GO:0000435 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter by galactose Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter. go-plus.json stimulation of transcription from RNA polymerase II promoter by galactose|up-regulation of transcription from RNA polymerase II promoter by galactose|activation of transcription from RNA polymerase II promoter by galactose|up regulation of transcription from RNA polymerase II promoter by galactose|upregulation of transcription from RNA polymerase II promoter by galactose http://purl.obolibrary.org/obo/GO_0000435 GO:0000434 biolink:BiologicalProcess carbon catabolite repression of transcription from RNA polymerase II promoter by galactose Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. go-plus.json down-regulation of transcription from RNA polymerase II promoter by galactose|downregulation of transcription from RNA polymerase II promoter by galactose|down regulation of transcription from RNA polymerase II promoter by galactose|inhibition of transcription from RNA polymerase II promoter by galactose http://purl.obolibrary.org/obo/GO_0000434 GO:0097341 biolink:BiologicalProcess zymogen inhibition Any process that prevents the proteolytic processing of an inactive enzyme to an active form. go-plus.json prevention of zymogen activation http://purl.obolibrary.org/obo/GO_0097341 GO:0000433 biolink:BiologicalProcess carbon catabolite repression of transcription from RNA polymerase II promoter by glucose A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. go-plus.json downregulation of transcription from RNA polymerase II promoter by glucose|down regulation of transcription from RNA polymerase II promoter by glucose|inhibition of transcription from RNA polymerase II promoter by glucose|down-regulation of transcription from RNA polymerase II promoter by glucose http://purl.obolibrary.org/obo/GO_0000433 GO:0097340 biolink:BiologicalProcess inhibition of cysteine-type endopeptidase activity Any process that prevents the activation of an inactive cysteine-type endopeptidase. go-plus.json prevention of cysteine-type endopeptidase activity|inhibition of caspase activity|prevention of caspase activity http://purl.obolibrary.org/obo/GO_0097340 GO:0000432 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter by glucose Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter. go-plus.json up regulation of transcription from RNA polymerase II promoter by glucose|upregulation of transcription from RNA polymerase II promoter by glucose|stimulation of transcription from RNA polymerase II promoter by glucose|up-regulation of transcription from RNA polymerase II promoter by glucose|activation of transcription from RNA polymerase II promoter by glucose http://purl.obolibrary.org/obo/GO_0000432 GO:0000439 biolink:CellularComponent transcription factor TFIIH core complex The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD. go-plus.json core TFIIH complex|SSL2-core TFIIH complex http://purl.obolibrary.org/obo/GO_0000439 goslim_pir GO:0000438 biolink:CellularComponent core TFIIH complex portion of holo TFIIH complex The core TFIIH complex when it is part of the general transcription factor TFIIH. go-plus.json SSL2-core TFIIH complex portion of holo TFIIH complex http://purl.obolibrary.org/obo/GO_0000438 GO:0000437 biolink:BiologicalProcess carbon catabolite repression of transcription from RNA polymerase II promoter A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. go-plus.json negative regulation of transcription from RNA polymerase II promoter by carbon catabolites http://purl.obolibrary.org/obo/GO_0000437 GO:0000436 biolink:BiologicalProcess carbon catabolite activation of transcription from RNA polymerase II promoter Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of transcription from RNA polymerase II promoter by carbon catabolites http://purl.obolibrary.org/obo/GO_0000436 GO:0097347 biolink:CellularComponent TAM protein secretion complex A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane. go-plus.json translocation and assembly module protein complex http://purl.obolibrary.org/obo/GO_0097347 GO:0097346 biolink:CellularComponent INO80-type complex A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0097346 GO:0097349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097349 GO:0097348 biolink:CellularComponent host cell endocytic vesicle membrane The lipid bilayer surrounding a host cell endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097348 GO:0097398 biolink:BiologicalProcess cellular response to interleukin-17 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus. go-plus.json cellular response to IL-17 http://purl.obolibrary.org/obo/GO_0097398 UBERON:0001749 biolink:AnatomicalEntity parenchyma of parathyroid gland A parenchyma that is part of a parathyroid gland [Automatically generated definition]. go-plus.json parathyroid gland parenchyma|parathyroid parenchyma|parenchyma of parathyroid http://purl.obolibrary.org/obo/UBERON_0001749 CHEBI:48379 biolink:ChemicalSubstance isourea go-plus.json http://purl.obolibrary.org/obo/CHEBI_48379 GO:0097397 biolink:BiologicalProcess cellular response to interleukin-32 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus. go-plus.json cellular response to IL-32 http://purl.obolibrary.org/obo/GO_0097397 CHEBI:48378 biolink:ChemicalSubstance carboximidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48378 UBERON:0001748 biolink:AnatomicalEntity capsule of parathyroid gland The dense and irregular connective tissue capsule surrounding a parathyroid gland. go-plus.json parathyroid gland capsule http://purl.obolibrary.org/obo/UBERON_0001748 GO:0097399 biolink:BiologicalProcess interleukin-32-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-32 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-32-mediated signaling pathway|IL-32-mediated signalling pathway|interleukin-32-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0097399 UBERON:0001745 biolink:AnatomicalEntity secondary nodular lymphoid tissue A lymphoid follicle that contains a germinal center. go-plus.json peripheral lymphoid tissue|secondary lymphoid nodule|secondary lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0001745 GO:0097394 biolink:BiologicalProcess telomeric repeat-containing RNA transcription by RNA polymerase II The synthesis of telomeric repeat-containing RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II promoter. go-plus.json telomeric repeat-containing RNA transcription from RNA pol II promoter|TERRA RNA transcription from RNA pol II promoter|telomeric RNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0097394 GO:0000402 biolink:MolecularActivity crossed form four-way junction DNA binding Binding to a DNA segment containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands. go-plus.json crossed form Holliday junction binding http://purl.obolibrary.org/obo/GO_0000402 GO:0000401 biolink:MolecularActivity open form four-way junction DNA binding Binding to a DNA segment containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over. go-plus.json open form Holliday junction binding http://purl.obolibrary.org/obo/GO_0000401 GO:0097393 biolink:BiologicalProcess telomeric repeat-containing RNA transcription The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome. go-plus.json TERRA transcription http://purl.obolibrary.org/obo/GO_0097393 UBERON:0001744 biolink:AnatomicalEntity lymphoid tissue Portion of connective tissue with various types of white blood cells enmeshed in it, most numerous being the lymphocytes[WP]. go-plus.json lymphocytic tissue|lymphatic tissue http://purl.obolibrary.org/obo/UBERON_0001744 UBERON:0001747 biolink:AnatomicalEntity parenchyma of thyroid gland A parenchyma that is part of a thyroid follicle [Automatically generated definition]. go-plus.json thyroid gland parenchyma|parenchyma of thyroid follicle|thyroid parenchyma|thyroid follicle parenchyma|parenchyma glandulae thyroideae|parenchyma of thyroid|parenchyma of thyroid gland follicle|thyroid gland follicle parenchyma http://purl.obolibrary.org/obo/UBERON_0001747 GO:0000400 biolink:MolecularActivity four-way junction DNA binding Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. go-plus.json forked DNA binding|Holliday junction binding http://purl.obolibrary.org/obo/GO_0000400 GO:0097396 biolink:BiologicalProcess response to interleukin-17 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus. go-plus.json response to IL-17 http://purl.obolibrary.org/obo/GO_0097396 UBERON:0001746 biolink:AnatomicalEntity capsule of thyroid gland go-plus.json capsula fibrosa glandulae thyroideae|thyroid capsule|fibrous capsule of thyroid gland|thyroid gland capsule http://purl.obolibrary.org/obo/UBERON_0001746 GO:0097395 biolink:BiologicalProcess response to interleukin-32 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus. go-plus.json response to IL-32 http://purl.obolibrary.org/obo/GO_0097395 GO:0097390 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 12 production The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CXCL12 production http://purl.obolibrary.org/obo/GO_0097390 gocheck_do_not_annotate GO:0097392 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 16 production The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CXCL16 production http://purl.obolibrary.org/obo/GO_0097392 gocheck_do_not_annotate GO:0097391 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 13 production The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CXCL13 production http://purl.obolibrary.org/obo/GO_0097391 gocheck_do_not_annotate CHEBI:48377 biolink:ChemicalSubstance imidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48377 CHEBI:48376 biolink:ChemicalSubstance carbamimidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48376 CHEBI:63932 biolink:ChemicalSubstance EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63932 CHEBI:63931 biolink:ChemicalSubstance L-erythro-biopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63931 chebi_ph7_3 CHEBI:63933 biolink:ChemicalSubstance Aroclor 1254 go-plus.json http://purl.obolibrary.org/obo/CHEBI_63933 chebi_ph7_3 UBERON:0001752 biolink:AnatomicalEntity enamel A dentine-like hypermineralized substance that covers the tooth tip. Enamel's primary mineral is hydroxylapatite, which is a crystalline calcium phosphate. Unlike dentin and bone, enamel does not contain collagen. Instead, it has two unique classes of proteins called amelogenins and enamelins[WP]. go-plus.json tooth enamel|enameloid|enamel tissue|enamel of tooth http://purl.obolibrary.org/obo/UBERON_0001752 GO:0000406 biolink:MolecularActivity double-strand/single-strand DNA junction binding Binding to a DNA segment that contains double-stranded DNA flanked by a region of single-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000406 UBERON:0001751 biolink:AnatomicalEntity dentine Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular. go-plus.json predentin|dentin|dentine of tooth http://purl.obolibrary.org/obo/UBERON_0001751 GO:0000405 biolink:MolecularActivity bubble DNA binding Binding to DNA segment that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000405 GO:0000404 biolink:MolecularActivity heteroduplex DNA loop binding Binding to a DNA segment containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration. go-plus.json loop DNA binding http://purl.obolibrary.org/obo/GO_0000404 GO:0000403 biolink:MolecularActivity Y-form DNA binding Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end. go-plus.json forked DNA binding|splayed Y-form DNA binding http://purl.obolibrary.org/obo/GO_0000403 GO:0000409 biolink:BiologicalProcess regulation of transcription by galactose Any process involving galactose that modulates the frequency, rate or extent or transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0000409 UBERON:0001750 biolink:AnatomicalEntity lacrimal apparatus A network of orbital structures of the eye that secrete and drain tears from the surface of the eyeball into the nasal cavity; these parts include the lacrimal glands, lacrimal lake, lacrimal ducts, lacrimal canals, lacrimal sacs, nasolacrimal ducts, and lacrimal puncta. go-plus.json apparatus lacrimalis|lacrimal drainage system|lacrymal system|nasolacrimal system|nasolacrimal drainage system http://purl.obolibrary.org/obo/UBERON_0001750 GO:0000408 biolink:CellularComponent EKC/KEOPS complex A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p. go-plus.json KEOPS/EKC complex|endopeptidase-like kinase chromatin-associated protein complex|threonyl-carbamoly transferase complex|TCTC|kinase, putative endopeptidase and other proteins of small size protein complex http://purl.obolibrary.org/obo/GO_0000408 GO:0000407 biolink:CellularComponent phagophore assembly site Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction. go-plus.json pre-autophagosomal structure|perivacuolar space|PAS http://purl.obolibrary.org/obo/GO_0000407 UBERON:0001737 biolink:AnatomicalEntity larynx A continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001737 UBERON:0001739 biolink:AnatomicalEntity laryngeal cartilage The cartilaginous structures that support the larynx. go-plus.json larynx cartilage|cartilage of larynx|cartilagines laryngeales http://purl.obolibrary.org/obo/UBERON_0001739 GO:0000413 biolink:BiologicalProcess protein peptidyl-prolyl isomerization The modification of a protein by cis-trans isomerization of a proline residue. go-plus.json protein proline isomerization http://purl.obolibrary.org/obo/GO_0000413 GO:0000412 biolink:BiologicalProcess histone peptidyl-prolyl isomerization The modification of a histone by cis-trans isomerization of a proline residue. go-plus.json histone proline isomerization http://purl.obolibrary.org/obo/GO_0000412 UBERON:0001733 biolink:AnatomicalEntity soft palate The muscular, non-bony arch-shaped posterior portion of the palate extending from the posterior edge of the hard palate. go-plus.json velum palatinum|muscular palate|velum|palatum molle http://purl.obolibrary.org/obo/UBERON_0001733 UBERON:0001736 biolink:AnatomicalEntity submandibular gland Either of the paired compound tubuloalveolar (aka tubuloacinar) major salivary glands composed of both serous and mucous secretory cells and situated beneath the mandible. go-plus.json mandibular gland|maxillary gland|submaxillary gland|glandula submandibularis|submandibular salivary gland|mandibular salivary gland http://purl.obolibrary.org/obo/UBERON_0001736 GO:0000411 biolink:BiologicalProcess positive regulation of transcription by galactose Any process involving galactose that activates or increases the rate of transcription. go-plus.json up regulation of transcription by galactose|upregulation of transcription by galactose|stimulation of transcription by galactose|activation of transcription by galactose|up-regulation of transcription by galactose http://purl.obolibrary.org/obo/GO_0000411 GO:0000410 biolink:BiologicalProcess carbon catabolite repression of transcription by galactose A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. go-plus.json down-regulation of transcription by galactose|downregulation of transcription by galactose|down regulation of transcription by galactose|inhibition of transcription by galactose http://purl.obolibrary.org/obo/GO_0000410 CHEBI:48360 biolink:ChemicalSubstance amphiprotic solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48360 CHEBI:48362 biolink:ChemicalSubstance but-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48362 chebi_ph7_3 CHEBI:48361 biolink:ChemicalSubstance butene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48361 CHEBI:63947 biolink:ChemicalSubstance 2,2'-disulfoazobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63947 CHEBI:63944 biolink:ChemicalSubstance macrocyclic lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_63944 GO:0000417 biolink:CellularComponent HIR complex A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p. go-plus.json HIRA complex http://purl.obolibrary.org/obo/GO_0000417 GO:0000416 biolink:BiologicalProcess positive regulation of histone H3-K36 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. go-plus.json stimulation of histone H3-K36 methylation|up-regulation of histone H3-K36 methylation|activation of histone H3-K36 methylation|up regulation of histone H3-K36 methylation|upregulation of histone H3-K36 methylation http://purl.obolibrary.org/obo/GO_0000416 UBERON:0001743 biolink:AnatomicalEntity ligament of larynx A ligament that is part of a larynx and connexts the cartilages of the larynx go-plus.json laryngeal ligament|larynx ligament http://purl.obolibrary.org/obo/UBERON_0001743 GO:0000415 biolink:BiologicalProcess negative regulation of histone H3-K36 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. go-plus.json down-regulation of histone H3-K36 methylation|downregulation of histone H3-K36 methylation|down regulation of histone H3-K36 methylation|inhibition of histone H3-K36 methylation http://purl.obolibrary.org/obo/GO_0000415 GO:0000414 biolink:BiologicalProcess regulation of histone H3-K36 methylation Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. go-plus.json http://purl.obolibrary.org/obo/GO_0000414 GO:0000419 biolink:CellularComponent RNA polymerase V complex RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits. go-plus.json DNA-directed RNA polymerase V complex|DNA-directed RNA polymerase IVb complex http://purl.obolibrary.org/obo/GO_0000419 GO:0000418 biolink:CellularComponent RNA polymerase IV complex RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex. go-plus.json DNA-directed RNA polymerase IVa complex|DNA-directed RNA polymerase IV complex http://purl.obolibrary.org/obo/GO_0000418 UBERON:0001727 biolink:AnatomicalEntity taste bud A specialized receptor organ that is a collection of cells spanning the gustatory epithelium. go-plus.json tastebuds|taste buds|caliculus gustatorius|tastebud|taste-bud http://purl.obolibrary.org/obo/UBERON_0001727 GO:0097376 biolink:BiologicalProcess interneuron axon guidance The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions. go-plus.json http://purl.obolibrary.org/obo/GO_0097376 CHEBI:48357 biolink:ChemicalSubstance aprotic solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48357 GO:0097375 biolink:BiologicalProcess spinal sensory neuron axon guidance The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0097375 UBERON:0001726 biolink:AnatomicalEntity papilla of tongue go-plus.json lingual papilla|tongue papilla http://purl.obolibrary.org/obo/UBERON_0001726 CHEBI:48356 biolink:ChemicalSubstance protic solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48356 GO:0097378 biolink:BiologicalProcess dorsal spinal cord interneuron axon guidance The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord. go-plus.json dorsal interneuron axon guidance http://purl.obolibrary.org/obo/GO_0097378 CHEBI:48359 biolink:ChemicalSubstance protophilic solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48359 UBERON:0001728 biolink:AnatomicalEntity nasopharynx the section of the pharynx that lies above the soft palate go-plus.json nasal part of pharynx|Nasenrachenraum|rhinopharynx|epipharynx|pars nasalis pharyngis http://purl.obolibrary.org/obo/UBERON_0001728 GO:0097377 biolink:BiologicalProcess spinal cord interneuron axon guidance The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0097377 CHEBI:48358 biolink:ChemicalSubstance polar aprotic solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48358 CHEBI:24387 biolink:ChemicalSubstance glycolaldehydes go-plus.json http://purl.obolibrary.org/obo/CHEBI_24387 GO:0097372 biolink:MolecularActivity NAD-dependent histone deacetylase activity (H3-K18 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein. go-plus.json http://purl.obolibrary.org/obo/GO_0097372 UBERON:0001723 biolink:AnatomicalEntity tongue A muscular organ in the floor of the mouth. go-plus.json glossus http://purl.obolibrary.org/obo/UBERON_0001723 GO:0097371 biolink:MolecularActivity MDM2/MDM4 family protein binding Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53. go-plus.json http://purl.obolibrary.org/obo/GO_0097371 OBO:uberon/core#distally_connected_to biolink:OntologyClass distally connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. distally_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#distally_connected_to GO:0097374 biolink:BiologicalProcess sensory neuron axon guidance The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses. go-plus.json http://purl.obolibrary.org/obo/GO_0097374 UBERON:0001725 biolink:AnatomicalEntity cranial synchondrosis The cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001725 GO:0097373 biolink:CellularComponent MCM core complex A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated. go-plus.json MCM4/6/7 complex http://purl.obolibrary.org/obo/GO_0097373 GO:0097370 biolink:BiologicalProcess protein O-GlcNAcylation via threonine The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0097370 CHEBI:63950 biolink:ChemicalSubstance 2,2'-disulfonatoazobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63950 chebi_ph7_3 CHEBI:48353 biolink:ChemicalSubstance serine proteinase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_48353 CHEBI:24385 biolink:ChemicalSubstance glycoglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24385 CHEBI:24384 biolink:ChemicalSubstance glycogens go-plus.json http://purl.obolibrary.org/obo/CHEBI_24384 CHEBI:48355 biolink:ChemicalSubstance non-polar solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48355 CHEBI:48354 biolink:ChemicalSubstance polar solvent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48354 CHEBI:63954 biolink:ChemicalSubstance ionomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63954 CHEBI:63953 biolink:ChemicalSubstance 2-amino-6-chloro-4-(3-sulfoanilino)-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63953 CHEBI:63951 biolink:ChemicalSubstance estrogen receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_63951 CHEBI:63955 biolink:ChemicalSubstance 2-amino-6-chloro-4-(3-sulfonatoanilino)-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63955 chebi_ph7_3 UBERON:0001731 biolink:AnatomicalEntity cavity of pharynx A anatomical space that is enclosed by a pharynx. go-plus.json cavitas pharyngealis|pharyngeal cavity|lumen of pharynx|cavitas pharyngis http://purl.obolibrary.org/obo/UBERON_0001731 GO:0097379 biolink:BiologicalProcess dorsal spinal cord interneuron posterior axon guidance The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. go-plus.json dorsal interneuron caudal axon projection http://purl.obolibrary.org/obo/GO_0097379 UBERON:0001716 biolink:AnatomicalEntity secondary palate The part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. go-plus.json roof of mouth|palatum|palatum definitivum|palatum secundarium|palatum|definitive palate|palate|oral roof http://purl.obolibrary.org/obo/UBERON_0001716 GO:0097387 biolink:CellularComponent capitate projection Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies). go-plus.json http://purl.obolibrary.org/obo/GO_0097387 UBERON:0001715 biolink:AnatomicalEntity oculomotor nuclear complex Nuclear complex containing subnuclei that give rise to the axons of the occulomotor nerve, both motor and parasympathetic fibers, situated at the midline at the level of the superior colliculus in the midbrain tegmentum (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 533-534). go-plus.json oculomotor nucleus|nucleus oculomotorius|nucleus of oculomotor nuclear complex|OM|third cranial nerve nucleus|nucleus of oculomotor nerve|nIII|nucleus nervi oculomotorii|oculomotor III nuclear complex|nucleus of third cranial nerve|oculomotor III nucleus|motor nucleus III|oculomotor motornucleus http://purl.obolibrary.org/obo/UBERON_0001715 GO:0097386 biolink:CellularComponent glial cell projection A prolongation or process extending from a glial cell. go-plus.json glial projection|glial process http://purl.obolibrary.org/obo/GO_0097386 CHEBI:48345 biolink:ChemicalSubstance pyrazinecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48345 UBERON:0001718 biolink:AnatomicalEntity mesencephalic nucleus of trigeminal nerve Elongated nucleus located in the midbrain tegmentum that receives proprioceptive input from both teh extraocular and the masticatory muscles. Contrary to the general rule, the cell bodies that give rise to these sensory fibers are located within the mesencephalic nucleus rather than in a peripheral ganglion. Some of the sensory fibers in the mesencephalic root give off collaterals to the trigeminal motor nucleus, thereby providing the anatomic basis for the monosynaptic jaw reflex. (Heimer, L. The Human Brain and Spinal Cord, 2nd ed. 1996, page 248). go-plus.json trigeminal nerve mesencepahlic nucleus|mesencephalic trigeminal nucleus|trigeminal V mesencephalic nucleus|nucleus mesencephalicus nervi trigemini|mesencephalic nucleus of the trigeminal|mesencephalic trigeminal V nucleus|nucleus mesencephalicus nervi trigeminalis|mesencephalic nuclei of trigeminal nerves|midbrain trigeminal nucleus|nucleus of mesencephalic root of v|Me5|nucleus tractus mesencephalicus nervi trigemini|mesencephalic nucleus|trigeminal mesencephalic nucleus|nucleus tractus mesencephalici nervi trigemini|mesencephalic nucleus of the trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0001718 GO:0097389 biolink:BiologicalProcess chemokine (C-C motif) ligand 21 production The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CCL21 production http://purl.obolibrary.org/obo/GO_0097389 gocheck_do_not_annotate CHEBI:24399 biolink:ChemicalSubstance glycosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24399 UBERON:0001717 biolink:AnatomicalEntity spinal nucleus of trigeminal nerve Nucleus extending from the upper spinal cord through the pontine tegmentum that receives sensory inputs from the trigeminal nerve. It is continuous caudally with the dorsal gray matter of the spinal cord. go-plus.json trigeminal spinal sensory nucleus|spinal trigeminal nucleus|trigeminal nerve spinal tract nucleus|trigeminal v spinal sensory nucleus|spinal nucleus of cranial nerve v|nucleus spinalis nervi trigemini|trigeminal spinal nucleus|spinal nucleus of the trigeminal http://purl.obolibrary.org/obo/UBERON_0001717 GO:0097388 biolink:BiologicalProcess chemokine (C-C motif) ligand 19 production The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CCL19 production|ELC production|EBI1 ligand chemokine production|macrophage inflammatory protein-3-beta production|MIP-3-beta production http://purl.obolibrary.org/obo/GO_0097388 gocheck_do_not_annotate GO:0097383 biolink:MolecularActivity dIDP diphosphatase activity Catalysis of the reaction: dIDP + H2O = dIMP + phosphate. RHEA:35211|Reactome:R-HSA-2509793 go-plus.json deoxyinosine-diphosphatase activity http://purl.obolibrary.org/obo/GO_0097383 UBERON:0001711 biolink:AnatomicalEntity eyelid A fold of skin that covers and protects part of the eyeball. Examples: upper eyelid, lower eyelid, nictitating membrane go-plus.json blepharon|palpebra|palpebrae|eye lid|blephara http://purl.obolibrary.org/obo/UBERON_0001711 GO:0097382 biolink:MolecularActivity deoxynucleoside-diphosphatase activity Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0097382 UBERON:0001714 biolink:AnatomicalEntity cranial ganglion the groups of nerve cell bodies associated with the twelve cranial nerves go-plus.json cranial ganglia|cranial ganglion part of peripheral nervous system|cranial ganglion|cranial ganglion/nerve|ganglion of cranial neural tree organ|presumptive cranial ganglia|cranial nerve ganglion|head ganglion|ganglion of cranial nerve|cranial neural ganglion|cranial neural tree organ ganglion http://purl.obolibrary.org/obo/UBERON_0001714 GO:0097385 biolink:BiologicalProcess programmed necrotic cell death in response to starvation A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment). go-plus.json necrotic cell death in response to starvation http://purl.obolibrary.org/obo/GO_0097385 GO:0097384 biolink:BiologicalProcess cellular lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells. go-plus.json cellular lipid synthesis|cellular lipid formation|cellular lipid biosynthesis|cellular lipid anabolism http://purl.obolibrary.org/obo/GO_0097384 GO:0097381 biolink:CellularComponent photoreceptor disc membrane Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0097381 GO:0097380 biolink:BiologicalProcess dorsal spinal cord interneuron anterior axon guidance The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. go-plus.json dorsal interneuron rostral axon projection http://purl.obolibrary.org/obo/GO_0097380 CHEBI:24397 biolink:ChemicalSubstance glycophospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24397 UBERON:0001719 biolink:AnatomicalEntity nucleus ambiguus A region of histologically disparate cells located just dorsal to the inferior olivary nucleus in the lateral portion of the upper medulla. It receives upper motor neuron innervation directly via the corticobulbar tract This nucleus gives rise to the efferent motor fibers of the vagus nerve terminating in the laryngeal and pharyngeal muscles, as well as to the efferent motor fibers of the glossopharyngeal nerve (CN IX) terminating in the stylopharyngeus. [WP,unvetted]. go-plus.json ambiguous nucleus|ambiguus nucleus|Amb|nucleus innominatus http://purl.obolibrary.org/obo/UBERON_0001719 CHEBI:24396 biolink:ChemicalSubstance glycopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24396 CHEBI:48343 biolink:ChemicalSubstance disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48343 CHEBI:63962 biolink:ChemicalSubstance Hsp90 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_63962 CHEBI:63969 biolink:ChemicalSubstance (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63969 CHEBI:63966 biolink:ChemicalSubstance (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63966 UBERON:0001720 biolink:AnatomicalEntity cochlear nucleus Any of the nuclei of the cochlear nuclear complex. go-plus.json cochlear VIII nucleus|cochlear nucleus of acoustic nerve|statoacoustic (VIII) nucleus|nucleus of cochlear nerve|vestibulocochlear nucleus|cochlear nucleus of eighth cranial nerve http://purl.obolibrary.org/obo/UBERON_0001720 GO:0048343 biolink:BiologicalProcess paraxial mesodermal cell fate commitment The process in which a cell becomes committed to become a paraxial mesoderm cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048343 GO:0048342 biolink:BiologicalProcess paraxial mesodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048342 GO:0048341 biolink:BiologicalProcess paraxial mesoderm formation The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048341 GO:0048340 biolink:BiologicalProcess paraxial mesoderm morphogenesis The process in which the anatomical structures of the paraxial mesoderm are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048340 GO:1903749 biolink:BiologicalProcess positive regulation of establishment of protein localization to mitochondrion Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion. go-plus.json up regulation of establishment of protein localization in mitochondrion|up-regulation of establishment of protein localisation to mitochondrion|activation of establishment of protein localisation to mitochondrion|upregulation of establishment of protein localization in mitochondrion|up regulation of establishment of protein localization to mitochondrion|positive regulation of establishment of protein localisation to mitochondrion|up regulation of establishment of protein localisation to mitochondrion|up-regulation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localization to mitochondrion|activation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localisation to mitochondrion|up-regulation of establishment of protein localization to mitochondrion|positive regulation of establishment of protein localization in mitochondrion|activation of establishment of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903749 GO:1903748 biolink:BiologicalProcess negative regulation of establishment of protein localization to mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion. go-plus.json downregulation of establishment of protein localization in mitochondrion|down-regulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localization in mitochondrion|inhibition of establishment of protein localization in mitochondrion|negative regulation of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localisation to mitochondrion|downregulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localization to mitochondrion|inhibition of establishment of protein localization to mitochondrion|downregulation of establishment of protein localisation to mitochondrion|down regulation of establishment of protein localisation to mitochondrion|inhibition of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localization in mitochondrion|negative regulation of establishment of protein localization in mitochondrion http://purl.obolibrary.org/obo/GO_1903748 GO:1903747 biolink:BiologicalProcess regulation of establishment of protein localization to mitochondrion Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion. go-plus.json regulation of establishment of protein localization in mitochondrion|regulation of establishment of protein localisation to mitochondrion http://purl.obolibrary.org/obo/GO_1903747 GO:1903746 biolink:BiologicalProcess positive regulation of pharyngeal pumping Any process that activates or increases the frequency, rate or extent of pharyngeal pumping. go-plus.json up-regulation of pharyngeal pumping|activation of pharyngeal pumping|upregulation of pumping behavior|up regulation of pharyngeal pumping|up-regulation of pumping behavior|activation of pumping behavior|upregulation of pharyngeal pumping|positive regulation of pumping behavior|up regulation of pumping behavior http://purl.obolibrary.org/obo/GO_1903746 GO:1903745 biolink:BiologicalProcess negative regulation of pharyngeal pumping Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping. go-plus.json down regulation of pumping behavior|down-regulation of pharyngeal pumping|inhibition of pumping behavior|downregulation of pharyngeal pumping|down regulation of pharyngeal pumping|negative regulation of pumping behavior|down-regulation of pumping behavior|inhibition of pharyngeal pumping|downregulation of pumping behavior http://purl.obolibrary.org/obo/GO_1903745 GO:0048349 biolink:BiologicalProcess regulation of paraxial mesodermal cell fate specification Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0048349 GO:1903744 biolink:BiologicalProcess positive regulation of anterograde synaptic vesicle transport Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport. go-plus.json up-regulation of anterograde synaptic vesicle transport|activation of anterograde synaptic vesicle transport|up regulation of anterograde synaptic vesicle transport|upregulation of anterograde synaptic vesicle transport http://purl.obolibrary.org/obo/GO_1903744 GO:1903743 biolink:BiologicalProcess negative regulation of anterograde synaptic vesicle transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport. go-plus.json down-regulation of anterograde synaptic vesicle transport|downregulation of anterograde synaptic vesicle transport|down regulation of anterograde synaptic vesicle transport|inhibition of anterograde synaptic vesicle transport http://purl.obolibrary.org/obo/GO_1903743 GO:0048348 biolink:BiologicalProcess paraxial mesodermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0048348 GO:1903742 biolink:BiologicalProcess regulation of anterograde synaptic vesicle transport Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport. go-plus.json http://purl.obolibrary.org/obo/GO_1903742 goslim_synapse GO:0048347 biolink:BiologicalProcess negative regulation of paraxial mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination. go-plus.json down-regulation of paraxial mesodermal cell fate determination|inhibition of paraxial mesodermal cell fate determination|down regulation of paraxial mesodermal cell fate determination|downregulation of paraxial mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048347 GO:1903741 biolink:BiologicalProcess negative regulation of phosphatidate phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity. go-plus.json down regulation of phosphatidate phosphatase activity|inhibition of phosphatidate phosphatase activity|down-regulation of phosphatidic acid phosphatase activity|downregulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of phosphatidic acid phosphatase activity|downregulation of acid phosphatidyl phosphatase activity|inhibition of phosphatidate phosphohydrolase activity|down regulation of phosphatic acid phosphohydrolase activity|downregulation of phosphatic acid phosphatase activity|down regulation of 3-sn-phosphatidate phosphohydrolase activity|down regulation of acid phosphatidyl phosphatase activity|inhibition of acid phosphatidyl phosphatase activity|inhibition of 3-sn-phosphatidate phosphohydrolase activity|downregulation of phosphatic acid phosphohydrolase activity|down regulation of phosphatic acid phosphatase activity|inhibition of phosphatic acid phosphatase activity|downregulation of phosphatidic acid phosphatase activity|down regulation of phosphatidic acid phosphatase activity|down regulation of phosphatidate phosphohydrolase activity|inhibition of phosphatidic acid phosphatase activity|negative regulation of phosphatic acid phosphohydrolase activity|down-regulation of phosphatic acid phosphohydrolase activity|down-regulation of phosphatidate phosphatase activity|downregulation of phosphatidate phosphohydrolase activity|inhibition of phosphatic acid phosphohydrolase activity|down-regulation of acid phosphatidyl phosphatase activity|down-regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of acid phosphatidyl phosphatase activity|downregulation of phosphatidate phosphatase activity|negative regulation of phosphatic acid phosphatase activity|negative regulation of phosphatidate phosphohydrolase activity|down-regulation of phosphatic acid phosphatase activity|down-regulation of phosphatidate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_1903741 GO:0048346 biolink:BiologicalProcess positive regulation of paraxial mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination. go-plus.json up regulation of paraxial mesodermal cell fate determination|activation of paraxial mesodermal cell fate determination|stimulation of paraxial mesodermal cell fate determination|up-regulation of paraxial mesodermal cell fate determination|upregulation of paraxial mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048346 GO:1903740 biolink:BiologicalProcess positive regulation of phosphatidate phosphatase activity Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity. go-plus.json up regulation of 3-sn-phosphatidate phosphohydrolase activity|up regulation of acid phosphatidyl phosphatase activity|positive regulation of phosphatic acid phosphatase activity|upregulation of phosphatidate phosphatase activity|upregulation of phosphatic acid phosphohydrolase activity|up regulation of phosphatic acid phosphatase activity|up-regulation of phosphatidate phosphohydrolase activity|positive regulation of phosphatidic acid phosphatase activity|up regulation of phosphatidic acid phosphatase activity|upregulation of acid phosphatidyl phosphatase activity|upregulation of 3-sn-phosphatidate phosphohydrolase activity|up-regulation of phosphatidate phosphatase activity|up regulation of phosphatic acid phosphohydrolase activity|activation of phosphatidate phosphatase activity|positive regulation of phosphatic acid phosphohydrolase activity|upregulation of phosphatic acid phosphatase activity|upregulation of phosphatidate phosphohydrolase activity|activation of phosphatic acid phosphohydrolase activity|up-regulation of acid phosphatidyl phosphatase activity|upregulation of phosphatidic acid phosphatase activity|up-regulation of 3-sn-phosphatidate phosphohydrolase activity|activation of 3-sn-phosphatidate phosphohydrolase activity|activation of acid phosphatidyl phosphatase activity|up-regulation of phosphatic acid phosphatase activity|up regulation of phosphatidate phosphohydrolase activity|activation of phosphatic acid phosphatase activity|up regulation of phosphatidate phosphatase activity|up-regulation of phosphatic acid phosphohydrolase activity|positive regulation of phosphatidate phosphohydrolase activity|activation of phosphatidate phosphohydrolase activity|up-regulation of phosphatidic acid phosphatase activity|activation of phosphatidic acid phosphatase activity|positive regulation of 3-sn-phosphatidate phosphohydrolase activity|positive regulation of acid phosphatidyl phosphatase activity http://purl.obolibrary.org/obo/GO_1903740 GO:0048345 biolink:BiologicalProcess regulation of paraxial mesodermal cell fate determination Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination. go-plus.json http://purl.obolibrary.org/obo/GO_0048345 GO:0048344 biolink:BiologicalProcess paraxial mesodermal cell fate determination The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0048344 GO:0048354 biolink:BiologicalProcess mucilage biosynthetic process involved in seed coat development The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development. go-plus.json mucilage formation during seed coat development|mucilage synthesis during seed coat development|mucilage anabolism during seed coat development|mucilage biosynthetic process during seed coat development http://purl.obolibrary.org/obo/GO_0048354 GO:0048353 biolink:CellularComponent primary endosperm nucleus Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac. go-plus.json http://purl.obolibrary.org/obo/GO_0048353 GO:0048352 biolink:BiologicalProcess paraxial mesoderm structural organization The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure. go-plus.json paraxial mesoderm structural organisation http://purl.obolibrary.org/obo/GO_0048352 GO:0048351 biolink:BiologicalProcess negative regulation of paraxial mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification. go-plus.json down regulation of paraxial mesodermal cell fate specification|downregulation of paraxial mesodermal cell fate specification|down-regulation of paraxial mesodermal cell fate specification|inhibition of paraxial mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048351 GO:0048350 biolink:BiologicalProcess positive regulation of paraxial mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification. go-plus.json upregulation of paraxial mesodermal cell fate specification|up regulation of paraxial mesodermal cell fate specification|activation of paraxial mesodermal cell fate specification|stimulation of paraxial mesodermal cell fate specification|up-regulation of paraxial mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048350 GO:1903759 biolink:BiologicalProcess obsolete signal transduction involved in regulation of aerobic respiration OBSOLETE. Any signal transduction that is involved in regulation of aerobic respiration. go-plus.json signaling cascade involved in regulation of aerobic respiration|signalling pathway involved in regulation of aerobic respiration|signaling pathway involved in regulation of aerobic respiration|signalling cascade involved in regulation of aerobic respiration http://purl.obolibrary.org/obo/GO_1903759 GO:1903758 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903758 GO:1903757 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903757 GO:1903756 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903756 GO:1903755 biolink:BiologicalProcess positive regulation of SUMO transferase activity Any process that activates or increases the frequency, rate or extent of SUMO transferase activity. go-plus.json positive regulation of SMT3 conjugating enzyme|upregulation of SUMO conjugating enzyme activity|activation of SMT3 conjugating enzyme|up regulation of SUMO transferase activity|activation of SUMO transferase activity|up-regulation of SUMO conjugating enzyme activity|up-regulation of SMT3 conjugating enzyme|activation of SUMO conjugating enzyme activity|upregulation of SMT3 conjugating enzyme|up-regulation of SUMO transferase activity|positive regulation of SUMO conjugating enzyme activity|up regulation of SUMO conjugating enzyme activity|up regulation of SMT3 conjugating enzyme|upregulation of SUMO transferase activity http://purl.obolibrary.org/obo/GO_1903755 GO:1903754 biolink:CellularComponent cortical microtubule plus-end The plus-end of a cortical microtubule. go-plus.json cortical microtubule plus end http://purl.obolibrary.org/obo/GO_1903754 GO:0048359 biolink:BiologicalProcess mucilage metabolic process involved in seed coat development The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development. go-plus.json mucilage metabolism during seed coat development|mucilage metabolic process during seed coat development http://purl.obolibrary.org/obo/GO_0048359 GO:0048358 biolink:BiologicalProcess mucilage pectin biosynthetic process The chemical reactions and pathways resulting in the formation of the pectin component of mucilage. go-plus.json mucilage pectin biosynthesis|mucilage pectin anabolism|mucilage pectin synthesis|mucilage pectin formation http://purl.obolibrary.org/obo/GO_0048358 GO:1903753 biolink:BiologicalProcess negative regulation of p38MAPK cascade Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade. go-plus.json negative regulation of p38 MAPK cascade|down-regulation of p38 MAPK cascade|down-regulation of p38 cascade|negative regulation of p38 cascade|down regulation of p38MAPK cascade|inhibition of p38 cascade|downregulation of p38MAPK cascade|downregulation of p38 MAPK cascade|down regulation of p38 MAPK cascade|inhibition of p38 MAPK cascade|down-regulation of p38MAPK cascade|down regulation of p38 cascade|inhibition of p38MAPK cascade|downregulation of p38 cascade http://purl.obolibrary.org/obo/GO_1903753 GO:1903752 biolink:BiologicalProcess positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. go-plus.json activation of H2O2-induced intrinsic apoptotic signaling pathway|up regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|positive regulation of H2O2-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to H2O2|up regulation of H2O2-induced intrinsic apoptotic signaling pathway|up-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up regulation of intrinsic apoptotic signaling pathway in response to H2O2|upregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of H2O2-induced intrinsic apoptotic signaling pathway|activation of intrinsic apoptotic signaling pathway in response to H2O2|positive regulation of intrinsic apoptotic signaling pathway in response to H2O2|up-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|activation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up-regulation of H2O2-induced intrinsic apoptotic signaling pathway|up regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|activation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|positive regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up-regulation of intrinsic apoptotic signaling pathway in response to H2O2 http://purl.obolibrary.org/obo/GO_1903752 GO:0048357 biolink:BiologicalProcess pedicel mucilage biosynthetic process The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem. go-plus.json pedicel mucilage formation|pedicel mucilage biosynthesis|pedicel mucilage anabolism|pedicel mucilage synthesis http://purl.obolibrary.org/obo/GO_0048357 GO:0048356 biolink:BiologicalProcess root epithelial mucilage biosynthetic process The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth. go-plus.json root epithelial mucilage biosynthesis|root epithelial mucilage anabolism|root epithelial mucilage synthesis|root epithelial mucilage formation http://purl.obolibrary.org/obo/GO_0048356 GO:1903751 biolink:BiologicalProcess negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. go-plus.json negative regulation of H2O2-induced intrinsic apoptotic signaling pathway|down-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down-regulation of H2O2-induced intrinsic apoptotic signaling pathway|negative regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to H2O2|down regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of H2O2-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of intrinsic apoptotic signaling pathway in response to H2O2|down regulation of H2O2-induced intrinsic apoptotic signaling pathway|down regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|inhibition of H2O2-induced intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway in response to H2O2|down-regulation of intrinsic apoptotic signaling pathway in response to H2O2|downregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to H2O2|down-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide http://purl.obolibrary.org/obo/GO_1903751 GO:0048355 biolink:BiologicalProcess root cap mucilage biosynthetic process The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth. go-plus.json root cap mucilage synthesis|root cap mucilage biosynthesis|root cap mucilage formation|root cap mucilage anabolism http://purl.obolibrary.org/obo/GO_0048355 GO:1903750 biolink:BiologicalProcess regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. go-plus.json regulation of intrinsic apoptotic signaling pathway in response to H2O2|regulation of H2O2-induced intrinsic apoptotic signaling pathway|regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|regulation of hydrogen peroxide-induced apoptosis http://purl.obolibrary.org/obo/GO_1903750 GO:1903760 biolink:BiologicalProcess regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. go-plus.json regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903760 GO:0000387 biolink:BiologicalProcess spliceosomal snRNP assembly The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome. go-plus.json spliceosomal snRNP biogenesis http://purl.obolibrary.org/obo/GO_0000387 GO:0048365 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048365 GO:0048364 biolink:BiologicalProcess root development The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0048364 GO:0000386 biolink:MolecularActivity second spliceosomal transesterification activity Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. go-plus.json lariat formation, 5'-splice site cleavage|3'-splice site cleavage, exon ligation http://purl.obolibrary.org/obo/GO_0000386 GO:0048363 biolink:BiologicalProcess mucilage pectin metabolic process The chemical reactions and pathways involving the pectin component of mucilage. go-plus.json mucilage pectin metabolism http://purl.obolibrary.org/obo/GO_0048363 GO:0000385 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000385 GO:0048362 biolink:BiologicalProcess pedicel mucilage metabolic process The chemical reactions and pathways involving mucilage that occur in the flower stem. go-plus.json pedicel mucilage metabolism http://purl.obolibrary.org/obo/GO_0048362 GO:0000384 biolink:MolecularActivity first spliceosomal transesterification activity Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon. go-plus.json lariat formation, 5'-splice site cleavage http://purl.obolibrary.org/obo/GO_0000384 GO:0048361 biolink:BiologicalProcess root epithelial mucilage metabolic process The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth. go-plus.json root epithelial mucilage metabolism http://purl.obolibrary.org/obo/GO_0048361 GO:0048360 biolink:BiologicalProcess root cap mucilage metabolic process The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth. go-plus.json root cap mucilage metabolism http://purl.obolibrary.org/obo/GO_0048360 GO:0000389 biolink:BiologicalProcess mRNA 3'-splice site recognition Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome. go-plus.json U12-type nuclear mRNA 3'-splice site recognition|nuclear mRNA 3'-splice site recognition|U2-type nuclear mRNA 3'-splice site recognition http://purl.obolibrary.org/obo/GO_0000389 GO:0000388 biolink:BiologicalProcess spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). go-plus.json U12-type spliceosome conformational change to release U4atac and U11|spliceosomal A1 complex formation|spliceosomal B2 complex formation|U2-type spliceosome conformational change to release U4 and U1|3'-splice site cleavage, exon ligation|spliceosomal A1 complex biosynthesis|spliceosomal B2 complex biosynthesis http://purl.obolibrary.org/obo/GO_0000388 GO:1903769 biolink:BiologicalProcess negative regulation of cell proliferation in bone marrow Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow. go-plus.json down regulation of cell proliferation in bone marrow|downregulation of cell proliferation in bone marrow|down-regulation of bone marrow cell proliferation|negative regulation of bone marrow cell proliferation|down-regulation of cell proliferation in bone marrow|downregulation of bone marrow cell proliferation|inhibition of cell proliferation in bone marrow|down regulation of bone marrow cell proliferation|inhibition of bone marrow cell proliferation http://purl.obolibrary.org/obo/GO_1903769 GO:1903768 biolink:CellularComponent taste receptor complex A protein complex which is capable of taste receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903768 GO:1903767 biolink:CellularComponent sweet taste receptor complex A protein complex which is capable of sweet taste receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903767 GO:1903766 biolink:BiologicalProcess positive regulation of potassium ion export across plasma membrane Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane. go-plus.json upregulation of potassium export|up regulation of potassium ion export across plasma membrane|upregulation of potassium ion export|activation of potassium export|up-regulation of potassium export|positive regulation of potassium ion export|activation of potassium ion export across plasma membrane|up-regulation of potassium ion export across plasma membrane|up-regulation of potassium ion export|activation of potassium ion export|positive regulation of potassium export|up regulation of potassium export|upregulation of potassium ion export across plasma membrane|up regulation of potassium ion export http://purl.obolibrary.org/obo/GO_1903766 GO:1903765 biolink:BiologicalProcess negative regulation of potassium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane. go-plus.json downregulation of potassium ion export|down regulation of potassium ion export|inhibition of potassium ion export|down-regulation of potassium ion export across plasma membrane|negative regulation of potassium ion export|down-regulation of potassium export|negative regulation of potassium export|inhibition of potassium export|inhibition of potassium ion export across plasma membrane|down-regulation of potassium ion export|downregulation of potassium export|down regulation of potassium ion export across plasma membrane|down regulation of potassium export|downregulation of potassium ion export across plasma membrane http://purl.obolibrary.org/obo/GO_1903765 GO:1903764 biolink:BiologicalProcess regulation of potassium ion export across plasma membrane Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane. go-plus.json regulation of potassium export across plasma membrane|regulation of potassium ion export|regulation of potassium export http://purl.obolibrary.org/obo/GO_1903764 GO:0048369 biolink:BiologicalProcess lateral mesoderm morphogenesis The process in which the anatomical structures of the lateral mesoderm are generated and organized. go-plus.json lateral plate mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048369 CHEBI:167498 biolink:ChemicalSubstance 1-(1,2-saturated-acyl)-2-acyl-sn-glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_167498 GO:0000383 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000383 GO:0048368 biolink:BiologicalProcess lateral mesoderm development The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. go-plus.json lateral plate mesoderm development http://purl.obolibrary.org/obo/GO_0048368 CHEBI:167497 biolink:ChemicalSubstance 1-O-(alk-1-enyl)-2-acyl-sn-glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_167497 GO:1903763 biolink:MolecularActivity gap junction channel activity involved in cell communication by electrical coupling Any gap junction channel activity that is involved in cell communication by electrical coupling. go-plus.json innexin channel activity involved in cell communication by electrical coupling|innexin involved in cell communication by electrical coupling|connexin involved in cell communication by electrical coupling http://purl.obolibrary.org/obo/GO_1903763 GO:0000382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000382 GO:0000381 biolink:BiologicalProcess regulation of alternative mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. go-plus.json regulation of alternative nuclear mRNA splicing, via spliceosome|splice site selection http://purl.obolibrary.org/obo/GO_0000381 GO:1903762 biolink:BiologicalProcess positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. go-plus.json up-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|up-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|activation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|positive regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|upregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903762 GO:0048367 biolink:BiologicalProcess shoot system development The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure. go-plus.json shoot development http://purl.obolibrary.org/obo/GO_0048367 GO:1903761 biolink:BiologicalProcess negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. go-plus.json inhibition of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|inhibition of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|downregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|downregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|inhibition of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|down-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903761 GO:0048366 biolink:BiologicalProcess leaf development The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048366 GO:0000380 biolink:BiologicalProcess alternative mRNA splicing, via spliceosome The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition. go-plus.json splice site selection|alternative nuclear mRNA splicing, via spliceosome http://purl.obolibrary.org/obo/GO_0000380 GO:1903771 biolink:BiologicalProcess positive regulation of beta-galactosidase activity Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity. go-plus.json upregulation of lactose hydrolysis|upregulation of lactozym|activation of S 2107|activation of beta-D-lactosidase activity|positive regulation of beta-D-lactosidase activity|activation of sumiklat|up-regulation of beta-D-galactoside galactohydrolase activity|up-regulation of hydrolact|activation of beta-D-galactoside galactohydrolase activity|up-regulation of oryzatym|up-regulation of maxilact|upregulation of beta-galactosidase activity|up-regulation of beta-D-galactanase activity|positive regulation of S 2107|up-regulation of trilactase activity|positive regulation of sumiklat|up-regulation of exo-(1->4)-beta-D-galactanase activity|up regulation of beta-lactosidase activity|up regulation of S 2107|activation of exo-(1->4)-beta-D-galactanase activity|up-regulation of lactozym|up-regulation of lactose hydrolysis|activation of oryzatym|up regulation of sumiklat|activation of maxilact|activation of beta-lactosidase activity|positive regulation of beta-lactosidase activity|upregulation of hydrolact|up-regulation of beta-D-lactosidase activity|upregulation of beta-D-galactanase activity|positive regulation of beta-D-galactoside galactohydrolase activity|positive regulation of maxilact|up regulation of beta-galactosidase activity|positive regulation of oryzatym|activation of lactose hydrolysis|activation of lactozym|up regulation of beta-D-galactoside galactohydrolase activity|upregulation of trilactase activity|activation of beta-galactosidase activity|up regulation of oryzatym|up regulation of maxilact|positive regulation of exo-(1->4)-beta-D-galactanase activity|upregulation of S 2107|upregulation of sumiklat|positive regulation of lactozym|up regulation of exo-(1->4)-beta-D-galactanase activity|positive regulation of lactose hydrolysis|upregulation of beta-D-lactosidase activity|up regulation of hydrolact|up-regulation of beta-lactosidase activity|up regulation of lactozym|up regulation of lactose hydrolysis|up regulation of beta-D-galactanase activity|positive regulation of hydrolact|up regulation of trilactase activity|upregulation of beta-D-galactoside galactohydrolase activity|activation of beta-D-galactanase activity|positive regulation of beta-D-galactanase activity|upregulation of oryzatym|upregulation of maxilact|positive regulation of trilactase activity|up-regulation of S 2107|up-regulation of beta-galactosidase activity|activation of trilactase activity|up-regulation of sumiklat|activation of hydrolact|upregulation of beta-lactosidase activity|upregulation of exo-(1->4)-beta-D-galactanase activity|up regulation of beta-D-lactosidase activity http://purl.obolibrary.org/obo/GO_1903771 GO:1903770 biolink:BiologicalProcess negative regulation of beta-galactosidase activity Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity. go-plus.json down regulation of beta-lactosidase activity|down-regulation of S 2107|negative regulation of S 2107|negative regulation of sumiklat|down-regulation of sumiklat|inhibition of beta-D-galactanase activity|inhibition of lactozym|inhibition of lactose hydrolysis|negative regulation of beta-D-lactosidase activity|downregulation of beta-lactosidase activity|down-regulation of beta-D-lactosidase activity|inhibition of trilactase activity|down regulation of beta-galactosidase activity|inhibition of hydrolact|negative regulation of beta-D-galactoside galactohydrolase activity|down-regulation of beta-D-galactoside galactohydrolase activity|negative regulation of maxilact|down-regulation of maxilact|down-regulation of oryzatym|negative regulation of oryzatym|downregulation of beta-galactosidase activity|downregulation of S 2107|inhibition of beta-D-lactosidase activity|downregulation of sumiklat|down-regulation of beta-lactosidase activity|negative regulation of exo-(1->4)-beta-D-galactanase activity|down regulation of hydrolact|down-regulation of exo-(1->4)-beta-D-galactanase activity|negative regulation of beta-lactosidase activity|down regulation of S 2107|down-regulation of lactose hydrolysis|negative regulation of lactozym|down-regulation of lactozym|down regulation of beta-D-galactanase activity|negative regulation of lactose hydrolysis|down regulation of sumiklat|downregulation of beta-D-galactoside galactohydrolase activity|down regulation of trilactase activity|downregulation of hydrolact|downregulation of maxilact|downregulation of oryzatym|downregulation of beta-D-galactanase activity|down-regulation of beta-galactosidase activity|inhibition of beta-lactosidase activity|inhibition of S 2107|downregulation of trilactase activity|down regulation of beta-D-galactoside galactohydrolase activity|inhibition of sumiklat|downregulation of exo-(1->4)-beta-D-galactanase activity|down regulation of maxilact|down regulation of oryzatym|down regulation of beta-D-lactosidase activity|inhibition of beta-D-galactoside galactohydrolase activity|downregulation of lactozym|downregulation of lactose hydrolysis|down-regulation of hydrolact|inhibition of beta-galactosidase activity|negative regulation of hydrolact|down regulation of exo-(1->4)-beta-D-galactanase activity|downregulation of beta-D-lactosidase activity|down regulation of lactose hydrolysis|negative regulation of beta-D-galactanase activity|inhibition of exo-(1->4)-beta-D-galactanase activity|down regulation of lactozym|down-regulation of beta-D-galactanase activity|inhibition of oryzatym|inhibition of maxilact|negative regulation of trilactase activity|down-regulation of trilactase activity http://purl.obolibrary.org/obo/GO_1903770 GO:0048376 biolink:BiologicalProcess positive regulation of lateral mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination. go-plus.json upregulation of lateral mesodermal cell fate determination|stimulation of lateral mesodermal cell fate determination|up-regulation of lateral mesodermal cell fate determination|activation of lateral mesodermal cell fate determination|positive regulation of lateral plate mesodermal cell fate determination|up regulation of lateral mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048376 GO:0000398 biolink:BiologicalProcess mRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. go-plus.json splicing GT-AG intron|mRNA splicing|nuclear mRNA splicing, via spliceosome|nuclear mRNA splicing via U2-type spliceosome|pre-mRNA splicing|nuclear mRNA splicing via U12-type spliceosome|splicing AT-AC intron http://purl.obolibrary.org/obo/GO_0000398 GO:0000397 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000397 GO:0048375 biolink:BiologicalProcess negative regulation of lateral mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination. go-plus.json negative regulation of lateral plate mesodermal cell fate determination|down-regulation of lateral mesodermal cell fate determination|downregulation of lateral mesodermal cell fate determination|down regulation of lateral mesodermal cell fate determination|inhibition of lateral mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048375 GO:0000396 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000396 GO:0048374 biolink:BiologicalProcess regulation of lateral mesodermal cell fate determination Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination. go-plus.json regulation of lateral mesoderm cell fate determination|regulation of lateral plate mesodermal cell fate determination|regulation of lateral plate mesoderm cell fate determination http://purl.obolibrary.org/obo/GO_0048374 GO:0048373 biolink:BiologicalProcess lateral mesodermal cell fate determination The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json lateral plate mesodermal cell fate determination|lateral plate mesoderm cell fate determination|lateral mesoderm cell fate determination http://purl.obolibrary.org/obo/GO_0048373 GO:0000395 biolink:BiologicalProcess mRNA 5'-splice site recognition Recognition of the intron 5'-splice site by components of the assembling spliceosome. go-plus.json U2-type nuclear mRNA 5'-splice site recognition|nuclear mRNA 5' splice site recognition|spliceosomal CC complex formation|U12-type nuclear mRNA 5' splice site recognition|spliceosomal commitment complex biosynthesis|spliceosomal E complex formation|spliceosomal E complex biosynthesis|spliceosomal commitment complex formation|U2-type nuclear mRNA 5' splice site recognition|U12-type nuclear mRNA 5'-splice site recognition|spliceosomal CC complex biosynthesis|nuclear mRNA 5'-splice site recognition http://purl.obolibrary.org/obo/GO_0000395 GO:0048372 biolink:BiologicalProcess lateral mesodermal cell fate commitment The process in which a cell becomes committed to become a lateral mesoderm cell. go-plus.json lateral plate mesodermal cell fate commitment|lateral mesoderm cell fate commitment|lateral plate mesoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0048372 GO:0048371 biolink:BiologicalProcess lateral mesodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell. go-plus.json lateral plate mesodermal cell differentiation|lateral mesoderm cell differentiation|lateral plate mesoderm cell differentiation http://purl.obolibrary.org/obo/GO_0048371 GO:0048370 biolink:BiologicalProcess lateral mesoderm formation The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. go-plus.json lateral plate mesoderm formation|lateral plate mesoderm biosynthesis http://purl.obolibrary.org/obo/GO_0048370 GO:0000399 biolink:CellularComponent cellular bud neck septin structure Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0000399 GO:0000390 biolink:BiologicalProcess spliceosomal complex disassembly Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. go-plus.json U12-type spliceosome disassembly|spliceosome disassembly|spliceosome complex disassembly|U2-type spliceosome disassembly http://purl.obolibrary.org/obo/GO_0000390 GO:1903779 biolink:BiologicalProcess regulation of cardiac conduction Any process that modulates the frequency, rate or extent of cardiac conduction. go-plus.json http://purl.obolibrary.org/obo/GO_1903779 GO:1903778 biolink:BiologicalProcess protein localization to vacuolar membrane A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. go-plus.json protein localisation in vacuolar membrane|protein localisation to vacuolar membrane|protein localization in vacuolar membrane http://purl.obolibrary.org/obo/GO_1903778 GO:1903777 biolink:MolecularActivity melibiose binding Binding to melibiose. go-plus.json http://purl.obolibrary.org/obo/GO_1903777 GO:1903776 biolink:BiologicalProcess regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends. go-plus.json http://purl.obolibrary.org/obo/GO_1903776 GO:1903775 biolink:BiologicalProcess regulation of DNA double-strand break processing Any process that modulates the frequency, rate or extent of DNA double-strand break processing. go-plus.json http://purl.obolibrary.org/obo/GO_1903775 GO:0000394 biolink:BiologicalProcess RNA splicing, via endonucleolytic cleavage and ligation Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. go-plus.json mRNA splicing http://purl.obolibrary.org/obo/GO_0000394 GO:1903774 biolink:BiologicalProcess positive regulation of viral budding via host ESCRT complex Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex. go-plus.json up-regulation of viral budding via host ESCRT complex|activation of viral budding via host ESCRT complex|up-regulation of viral budding through the ESCRT machinery|upregulation of viral budding through the ESCRT machinery|up regulation of viral budding via host ESCRT complex|up regulation of viral budding through the ESCRT machinery|upregulation of viral budding via host ESCRT complex|positive regulation of viral budding through the ESCRT machinery|activation of viral budding through the ESCRT machinery http://purl.obolibrary.org/obo/GO_1903774 GO:0000393 biolink:BiologicalProcess spliceosomal conformational changes to generate catalytic conformation Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation. go-plus.json 3'-splice site cleavage, exon ligation http://purl.obolibrary.org/obo/GO_0000393 GO:0048379 biolink:BiologicalProcess positive regulation of lateral mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification. go-plus.json upregulation of lateral mesodermal cell fate specification|stimulation of lateral mesodermal cell fate specification|up-regulation of lateral mesodermal cell fate specification|activation of lateral mesodermal cell fate specification|positive regulation of lateral plate mesodermal cell fate specification|up regulation of lateral mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048379 GO:1903773 biolink:BiologicalProcess negative regulation of viral budding via host ESCRT complex Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex. go-plus.json down-regulation of viral budding via host ESCRT complex|inhibition of viral budding through the ESCRT machinery|down regulation of viral budding through the ESCRT machinery|downregulation of viral budding via host ESCRT complex|downregulation of viral budding through the ESCRT machinery|down regulation of viral budding via host ESCRT complex|inhibition of viral budding via host ESCRT complex|negative regulation of viral budding through the ESCRT machinery|down-regulation of viral budding through the ESCRT machinery http://purl.obolibrary.org/obo/GO_1903773 GO:0048378 biolink:BiologicalProcess regulation of lateral mesodermal cell fate specification Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification. go-plus.json regulation of lateral plate mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048378 GO:0000392 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000392 GO:1903772 biolink:BiologicalProcess regulation of viral budding via host ESCRT complex Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex. go-plus.json regulation of host-assisted viral budding|regulation of viral budding through the ESCRT machinery http://purl.obolibrary.org/obo/GO_1903772 GO:0048377 biolink:BiologicalProcess lateral mesodermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json lateral plate mesodermal cell fate specification|lateral plate mesoderm cell fate specification|lateral mesoderm cell fate specification http://purl.obolibrary.org/obo/GO_0048377 GO:0000391 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000391 GO:1903782 biolink:BiologicalProcess regulation of sodium ion import across plasma membrane Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903782 GO:1903781 biolink:BiologicalProcess positive regulation of cardiac conduction Any process that activates or increases the frequency, rate or extent of cardiac conduction. go-plus.json upregulation of cardiac conduction|up-regulation of cardiac conduction|activation of cardiac conduction|up regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903781 GO:1903780 biolink:BiologicalProcess negative regulation of cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction. go-plus.json down regulation of cardiac conduction|inhibition of cardiac conduction|down-regulation of cardiac conduction|downregulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903780 GO:0048387 biolink:BiologicalProcess negative regulation of retinoic acid receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity. go-plus.json negative regulation of RAR signaling pathway|negative regulation of retinoic acid receptor signalling pathway|down-regulation of retinoic acid receptor signaling pathway|negative regulation of RAR signalling pathway|downregulation of retinoic acid receptor signaling pathway|down regulation of retinoic acid receptor signaling pathway|inhibition of retinoic acid receptor signaling pathway http://purl.obolibrary.org/obo/GO_0048387 GO:0000365 biolink:BiologicalProcess mRNA trans splicing, via spliceosome The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. go-plus.json nuclear mRNA trans splicing, via spliceosome|nuclear mRNA trans splicing, via U2-type spliceosome http://purl.obolibrary.org/obo/GO_0000365 GO:0097310 biolink:BiologicalProcess cap2 mRNA methylation Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA. go-plus.json cap2 mRNA capping http://purl.obolibrary.org/obo/GO_0097310 GO:0048386 biolink:BiologicalProcess positive regulation of retinoic acid receptor signaling pathway Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity. go-plus.json stimulation of retinoic acid receptor signaling pathway|positive regulation of RAR signaling pathway|positive regulation of retinoic acid receptor signalling pathway|up-regulation of retinoic acid receptor signaling pathway|activation of retinoic acid receptor signaling pathway|up regulation of retinoic acid receptor signaling pathway|upregulation of retinoic acid receptor signaling pathway http://purl.obolibrary.org/obo/GO_0048386 GO:0000364 biolink:MolecularActivity obsolete second U2-type spliceosomal transesterification activity OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins. go-plus.json second U2-type spliceosomal transesterification activity|3'-splice site cleavage, exon ligation http://purl.obolibrary.org/obo/GO_0000364 GO:0097312 biolink:CellularComponent obsolete bacterial biofilm matrix component OBSOLETE. Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria. go-plus.json biofilm matrix part http://purl.obolibrary.org/obo/GO_0097312 gocheck_do_not_annotate GO:0000363 biolink:MolecularActivity obsolete first U12-type spliceosomal transesterification activity OBSOLETE. Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins. go-plus.json first U12-type spliceosomal transesterification activity|lariat formation, 5'-splice site cleavage http://purl.obolibrary.org/obo/GO_0000363 GO:0048385 biolink:BiologicalProcess regulation of retinoic acid receptor signaling pathway Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity. go-plus.json regulation of RAR signaling pathway|regulation of retinoic acid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0048385 GO:0097311 biolink:CellularComponent bacterial biofilm matrix A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0097311 GO:0048384 biolink:BiologicalProcess retinoic acid receptor signaling pathway The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands. go-plus.json RAR signaling pathway|retinoic acid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0048384 GO:0000362 biolink:MolecularActivity obsolete first U2-type spliceosomal transesterification activity OBSOLETE. Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins. go-plus.json lariat formation, 5'-splice site cleavage|first U2-type spliceosomal transesterification activity http://purl.obolibrary.org/obo/GO_0000362 GO:0048383 biolink:BiologicalProcess mesectoderm development The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0048383 GO:0000369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000369 GO:0048382 biolink:BiologicalProcess mesendoderm development The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0048382 GO:0000368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000368 GO:0000367 biolink:MolecularActivity obsolete second U12-type spliceosomal transesterification activity OBSOLETE. Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins. go-plus.json second U12-type spliceosomal transesterification activity|3'-splice site cleavage, exon ligation http://purl.obolibrary.org/obo/GO_0000367 GO:0048381 biolink:BiologicalProcess lateral mesoderm structural organization The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure. go-plus.json lateral plate mesoderm structural organization|lateral mesoderm structural organisation http://purl.obolibrary.org/obo/GO_0048381 GO:0048380 biolink:BiologicalProcess negative regulation of lateral mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification. go-plus.json downregulation of lateral mesodermal cell fate specification|down regulation of lateral mesodermal cell fate specification|inhibition of lateral mesodermal cell fate specification|negative regulation of lateral plate mesodermal cell fate specification|down-regulation of lateral mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048380 GO:0000366 biolink:BiologicalProcess intergenic mRNA trans splicing The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing. go-plus.json intergenic nuclear mRNA trans splicing http://purl.obolibrary.org/obo/GO_0000366 GO:1903789 biolink:BiologicalProcess regulation of amino acid transmembrane transport Any process that modulates the frequency, rate or extent of amino acid transmembrane transport. go-plus.json regulation of amino acid membrane transport http://purl.obolibrary.org/obo/GO_1903789 GO:1903788 biolink:BiologicalProcess positive regulation of glutathione biosynthetic process Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process. go-plus.json up-regulation of glutathione synthesis|up-regulation of glutathione formation|upregulation of glutathione anabolism|positive regulation of glutathione biosynthesis|up regulation of glutathione biosynthesis|up regulation of glutathione biosynthetic process|upregulation of glutathione synthesis|upregulation of glutathione formation|up regulation of glutathione anabolism|upregulation of glutathione biosynthetic process|activation of glutathione anabolism|upregulation of glutathione biosynthesis|positive regulation of glutathione anabolism|up regulation of glutathione synthesis|activation of glutathione synthesis|positive regulation of glutathione synthesis|up regulation of glutathione formation|activation of glutathione formation|positive regulation of glutathione formation|up-regulation of glutathione biosynthesis|up-regulation of glutathione biosynthetic process|activation of glutathione biosynthesis|activation of glutathione biosynthetic process|up-regulation of glutathione anabolism http://purl.obolibrary.org/obo/GO_1903788 GO:1903787 biolink:BiologicalProcess negative regulation of glutathione biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process. go-plus.json inhibition of glutathione synthesis|negative regulation of glutathione biosynthesis|down-regulation of glutathione biosynthetic process|down-regulation of glutathione biosynthesis|inhibition of glutathione formation|down regulation of glutathione anabolism|downregulation of glutathione biosynthesis|downregulation of glutathione biosynthetic process|down regulation of glutathione synthesis|downregulation of glutathione anabolism|down regulation of glutathione biosynthetic process|down regulation of glutathione biosynthesis|inhibition of glutathione biosynthesis|down regulation of glutathione formation|inhibition of glutathione biosynthetic process|downregulation of glutathione synthesis|downregulation of glutathione formation|down-regulation of glutathione anabolism|negative regulation of glutathione anabolism|down-regulation of glutathione synthesis|negative regulation of glutathione synthesis|inhibition of glutathione anabolism|down-regulation of glutathione formation|negative regulation of glutathione formation http://purl.obolibrary.org/obo/GO_1903787 GO:1903786 biolink:BiologicalProcess regulation of glutathione biosynthetic process Any process that modulates the frequency, rate or extent of glutathione biosynthetic process. go-plus.json regulation of glutathione anabolism|regulation of glutathione biosynthesis|regulation of glutathione synthesis|regulation of glutathione formation http://purl.obolibrary.org/obo/GO_1903786 GO:0000361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000361 GO:1903785 biolink:BiologicalProcess L-valine transmembrane transport The directed movement of L-valine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903785 GO:0000360 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000360 GO:0048389 biolink:BiologicalProcess intermediate mesoderm development The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. go-plus.json http://purl.obolibrary.org/obo/GO_0048389 GO:1903784 biolink:BiologicalProcess positive regulation of sodium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane. go-plus.json upregulation of sodium ion import across plasma membrane|up-regulation of sodium ion import across plasma membrane|activation of sodium ion import across plasma membrane|up regulation of sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903784 GO:1903783 biolink:BiologicalProcess negative regulation of sodium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane. go-plus.json down regulation of sodium ion import across plasma membrane|inhibition of sodium ion import across plasma membrane|down-regulation of sodium ion import across plasma membrane|downregulation of sodium ion import across plasma membrane http://purl.obolibrary.org/obo/GO_1903783 GO:0048388 biolink:BiologicalProcess endosomal lumen acidification Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion. go-plus.json http://purl.obolibrary.org/obo/GO_0048388 GO:1903793 biolink:BiologicalProcess positive regulation of anion transport Any process that activates or increases the frequency, rate or extent of anion transport. go-plus.json activation of anion transport|up-regulation of anion transport|upregulation of anion transport|up regulation of anion transport http://purl.obolibrary.org/obo/GO_1903793 GO:1903792 biolink:BiologicalProcess negative regulation of anion transport Any process that stops, prevents or reduces the frequency, rate or extent of anion transport. go-plus.json down-regulation of anion transport|inhibition of anion transport|down regulation of anion transport|downregulation of anion transport http://purl.obolibrary.org/obo/GO_1903792 GO:1903791 biolink:BiologicalProcess uracil transmembrane transport The process in which uracil is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903791 GO:1903790 biolink:BiologicalProcess guanine nucleotide transmembrane transport The process in which a guanyl nucleotide is transported across a membrane. go-plus.json guanyl nucleotide transmembrane transport http://purl.obolibrary.org/obo/GO_1903790 GO:0048390 biolink:BiologicalProcess intermediate mesoderm morphogenesis The process in which the anatomical structures of the intermediate mesoderm are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048390 GO:0097318 biolink:BiologicalProcess invasive growth in response to abiotic stimulus The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans. go-plus.json http://purl.obolibrary.org/obo/GO_0097318 GO:0097317 biolink:BiologicalProcess invasive growth in response to biotic stimulus The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097317 GO:0097319 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097319 GO:0097314 biolink:BiologicalProcess apoptosome assembly The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process. go-plus.json apoptosome formation http://purl.obolibrary.org/obo/GO_0097314 GO:0097313 biolink:CellularComponent bacterial biofilm matrix surface The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0097313 GO:0097316 biolink:BiologicalProcess cellular response to N-acetyl-D-glucosamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097316 GO:0097315 biolink:BiologicalProcess response to N-acetyl-D-glucosamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097315 GO:0097321 biolink:BiologicalProcess cell growth mode switching, filamentous to budding The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans. go-plus.json http://purl.obolibrary.org/obo/GO_0097321 GO:0000376 biolink:BiologicalProcess RNA splicing, via transesterification reactions with guanosine as nucleophile Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile. go-plus.json http://purl.obolibrary.org/obo/GO_0000376 GO:0048398 biolink:BiologicalProcess intermediate mesodermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json intermediate mesoderm cell fate specification http://purl.obolibrary.org/obo/GO_0048398 GO:0000375 biolink:BiologicalProcess RNA splicing, via transesterification reactions Splicing of RNA via a series of two transesterification reactions. go-plus.json spliceosomal catalysis|RNA splicing factor activity, transesterification mechanism|pre-mRNA splicing factor activity http://purl.obolibrary.org/obo/GO_0000375 goslim_pir GO:0097320 biolink:BiologicalProcess plasma membrane tubulation A membrane tubulation process occurring in a plasma membrane. go-plus.json vesicle scission|membrane tubulation http://purl.obolibrary.org/obo/GO_0097320 GO:0048397 biolink:BiologicalProcess positive regulation of intermediate mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination. go-plus.json up regulation of intermediate mesodermal cell fate determination|activation of intermediate mesodermal cell fate determination|stimulation of intermediate mesodermal cell fate determination|up-regulation of intermediate mesodermal cell fate determination|upregulation of intermediate mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048397 GO:0048396 biolink:BiologicalProcess negative regulation of intermediate mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination. go-plus.json downregulation of intermediate mesodermal cell fate determination|down-regulation of intermediate mesodermal cell fate determination|inhibition of intermediate mesodermal cell fate determination|down regulation of intermediate mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048396 GO:0097323 biolink:BiologicalProcess B cell adhesion The attachment of a B cell to another cell via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0097323 GO:0000374 biolink:BiologicalProcess Group III intron splicing The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved. go-plus.json mRNA splicing http://purl.obolibrary.org/obo/GO_0000374 GO:0097322 biolink:MolecularActivity 7SK snRNA binding Binding to a 7SK small nuclear RNA (7SK snRNA). go-plus.json 7SK small nuclear RNA binding http://purl.obolibrary.org/obo/GO_0097322 GO:0048395 biolink:BiologicalProcess regulation of intermediate mesodermal cell fate determination Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination. go-plus.json http://purl.obolibrary.org/obo/GO_0048395 GO:0000373 biolink:BiologicalProcess Group II intron splicing The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. go-plus.json mRNA splicing http://purl.obolibrary.org/obo/GO_0000373 GO:0048394 biolink:BiologicalProcess intermediate mesodermal cell fate determination The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json intermediate mesoderm cell fate determination http://purl.obolibrary.org/obo/GO_0048394 GO:0048393 biolink:BiologicalProcess intermediate mesodermal cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell. go-plus.json intermediate mesoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0048393 GO:0000379 biolink:BiologicalProcess tRNA-type intron splice site recognition and cleavage RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0000379 GO:0048392 biolink:BiologicalProcess intermediate mesodermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell. go-plus.json intermediate mesoderm cell differentiation http://purl.obolibrary.org/obo/GO_0048392 GO:0000378 biolink:BiologicalProcess RNA exon ligation The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0000378 GO:0000377 biolink:BiologicalProcess RNA splicing, via transesterification reactions with bulged adenosine as nucleophile Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure. go-plus.json lariat RNA biosynthesis|lariat RNA formation http://purl.obolibrary.org/obo/GO_0000377 GO:0048391 biolink:BiologicalProcess intermediate mesoderm formation The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048391 GO:1903799 biolink:BiologicalProcess negative regulation of production of miRNAs involved in gene silencing by miRNA Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA. go-plus.json downregulation of microRNA metabolism|negative regulation of production of microRNAs involved in gene silencing by microRNA|down-regulation of production of microRNAs involved in gene silencing by microRNA|downregulation of production of miRNAs involved in gene silencing by miRNA|downregulation of miRNA-mediated gene silencing, production of miRNAs|inhibition of gene silencing by miRNA, production of miRNAs|down regulation of microRNA biogenesis|inhibition of microRNA metabolic process|negative regulation of microRNA biosynthesis|down-regulation of miRNA processing|down-regulation of microRNA biosynthesis|negative regulation of microRNA biosynthetic process|down regulation of production of miRNAs involved in gene silencing by miRNA|down-regulation of microRNA biosynthetic process|negative regulation of miRNA processing|inhibition of production of miRNAs involved in gene silencing by miRNA|downregulation of miRNA biogenesis|negative regulation of microRNA-mediated gene silencing, production of microRNAs|down-regulation of microRNA-mediated gene silencing, production of microRNAs|negative regulation of microRNA metabolism|downregulation of microRNA biogenesis|down-regulation of microRNA metabolism|downregulation of production of microRNAs involved in gene silencing by microRNA|down regulation of miRNA biogenesis|negative regulation of miRNA-mediated gene silencing, production of miRNAs|down-regulation of miRNA-mediated gene silencing, production of miRNAs|inhibition of microRNA-mediated gene silencing, production of microRNAs|down regulation of production of microRNAs involved in gene silencing by microRNA|inhibition of production of microRNAs involved in gene silencing by microRNA|downregulation of miRNA processing|negative regulation of microRNA metabolic process|down-regulation of microRNA metabolic process|inhibition of miRNA-mediated gene silencing, production of miRNAs|inhibition of miRNA biogenesis|down-regulation of microRNA biogenesis|inhibition of microRNA biosynthetic process|inhibition of microRNA biosynthesis|down regulation of gene silencing by miRNA, production of miRNAs|negative regulation of microRNA biogenesis|down regulation of miRNA processing|inhibition of miRNA processing|inhibition of microRNA metabolism|downregulation of gene silencing by miRNA, production of miRNAs|down regulation of microRNA biosynthetic process|down-regulation of production of miRNAs involved in gene silencing by miRNA|down regulation of microRNA biosynthesis|downregulation of microRNA metabolic process|down regulation of microRNA-mediated gene silencing, production of microRNAs|down regulation of microRNA metabolism|downregulation of microRNA biosynthetic process|downregulation of microRNA biosynthesis|negative regulation of miRNA biogenesis|down regulation of microRNA metabolic process|inhibition of microRNA biogenesis|down-regulation of miRNA biogenesis|negative regulation of gene silencing by miRNA, production of miRNAs|downregulation of microRNA-mediated gene silencing, production of microRNAs|down-regulation of gene silencing by miRNA, production of miRNAs|down regulation of miRNA-mediated gene silencing, production of miRNAs http://purl.obolibrary.org/obo/GO_1903799 GO:1903798 biolink:BiologicalProcess regulation of production of miRNAs involved in gene silencing by miRNA Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA. go-plus.json regulation of miRNA-mediated gene silencing, production of miRNAs|regulation of microRNA biogenesis|regulation of miRNA biogenesis|regulation of production of microRNAs involved in gene silencing by microRNA|regulation of miRNA processing|regulation of gene silencing by miRNA, production of miRNAs|regulation of microRNA processing|regulation of microRNA biosynthesis|regulation of microRNA biosynthetic process|regulation of microRNA metabolic process|regulation of microRNA-mediated gene silencing, production of microRNAs|regulation of microRNA metabolism http://purl.obolibrary.org/obo/GO_1903798 GO:1903797 biolink:BiologicalProcess positive regulation of inorganic anion transmembrane transport Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport. go-plus.json up regulation of inorganic anion transmembrane transport|up regulation of transmembrane inorganic anion transport|activation of inorganic anion transmembrane transport|activation of transmembrane inorganic anion transport|positive regulation of transmembrane inorganic anion transport|upregulation of inorganic anion membrane transport|up-regulation of inorganic anion membrane transport|activation of inorganic anion membrane transport|up-regulation of inorganic anion transmembrane transport|up-regulation of transmembrane inorganic anion transport|upregulation of inorganic anion transmembrane transport|upregulation of transmembrane inorganic anion transport|positive regulation of inorganic anion membrane transport|up regulation of inorganic anion membrane transport http://purl.obolibrary.org/obo/GO_1903797 GO:0000372 biolink:BiologicalProcess Group I intron splicing The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize). go-plus.json mRNA splicing http://purl.obolibrary.org/obo/GO_0000372 GO:1903796 biolink:BiologicalProcess negative regulation of inorganic anion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport. go-plus.json down regulation of inorganic anion membrane transport|inhibition of inorganic anion membrane transport|negative regulation of transmembrane inorganic anion transport|down-regulation of transmembrane inorganic anion transport|down-regulation of inorganic anion transmembrane transport|inhibition of transmembrane inorganic anion transport|inhibition of inorganic anion transmembrane transport|down-regulation of inorganic anion membrane transport|negative regulation of inorganic anion membrane transport|down regulation of transmembrane inorganic anion transport|down regulation of inorganic anion transmembrane transport|downregulation of inorganic anion membrane transport|downregulation of inorganic anion transmembrane transport|downregulation of transmembrane inorganic anion transport http://purl.obolibrary.org/obo/GO_1903796 GO:0000371 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000371 GO:0000370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000370 GO:1903795 biolink:BiologicalProcess regulation of inorganic anion transmembrane transport Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport. go-plus.json regulation of transmembrane inorganic anion transport|regulation of inorganic anion membrane transport http://purl.obolibrary.org/obo/GO_1903795 GO:0048399 biolink:BiologicalProcess regulation of intermediate mesodermal cell fate specification Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0048399 GO:1903794 biolink:MolecularActivity cortisol binding Binding to cortisol. go-plus.json http://purl.obolibrary.org/obo/GO_1903794 GO:0097329 biolink:BiologicalProcess response to antimetabolite Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. go-plus.json http://purl.obolibrary.org/obo/GO_0097329 GO:0097328 biolink:BiologicalProcess response to carboplatin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097328 GO:0097325 biolink:BiologicalProcess melanocyte proliferation The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. go-plus.json http://purl.obolibrary.org/obo/GO_0097325 GO:0097324 biolink:BiologicalProcess melanocyte migration The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. go-plus.json http://purl.obolibrary.org/obo/GO_0097324 GO:0097327 biolink:BiologicalProcess response to antineoplastic agent Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms. go-plus.json http://purl.obolibrary.org/obo/GO_0097327 GO:0097326 biolink:BiologicalProcess melanocyte adhesion The attachment of a melanocyte to another cell via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0097326 GO:0000343 biolink:CellularComponent plastid-encoded plastid RNA polymerase complex A A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex. go-plus.json PEP-A http://purl.obolibrary.org/obo/GO_0000343 GO:0000342 biolink:MolecularActivity RNA cap 4 binding Binding to a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa. go-plus.json http://purl.obolibrary.org/obo/GO_0000342 GO:0000341 biolink:MolecularActivity RNA trimethylguanosine cap binding Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans. go-plus.json RNA m2,2,7G cap binding http://purl.obolibrary.org/obo/GO_0000341 GO:0000340 biolink:MolecularActivity RNA 7-methylguanosine cap binding Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II. go-plus.json RNA m7G cap binding http://purl.obolibrary.org/obo/GO_0000340 GO:0000347 biolink:CellularComponent THO complex The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0000347 goslim_pir GO:0000346 biolink:CellularComponent transcription export complex The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans. go-plus.json TREX complex http://purl.obolibrary.org/obo/GO_0000346 goslim_pir GO:0000345 biolink:CellularComponent cytosolic DNA-directed RNA polymerase complex The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity. go-plus.json http://purl.obolibrary.org/obo/GO_0000345 GO:0000344 biolink:CellularComponent plastid-encoded plastid RNA polymerase complex B A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation. go-plus.json PEP-B http://purl.obolibrary.org/obo/GO_0000344 GO:0000349 biolink:BiologicalProcess generation of catalytic spliceosome for first transesterification step Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. go-plus.json formation of catalytic spliceosome for first transesterification step|spliceosomal C1 complex biosynthesis|spliceosomal A2-2 complex biosynthesis|spliceosomal A2-2 complex formation|catalytic spliceosome assembly for first transesterification step|U2-type catalytic spliceosome formation for first transesterification step|spliceosomal C1 complex formation|U12-type catalytic spliceosome formation for first transesterification step http://purl.obolibrary.org/obo/GO_0000349 GO:0000348 biolink:BiologicalProcess mRNA branch site recognition Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. go-plus.json nuclear mRNA branch site recognition|spliceosomal A complex biosynthesis|spliceosomal B complex biosynthesis|spliceosomal B complex formation|spliceosomal A complex formation|U2-type nuclear mRNA branch site recognition|U12-type nuclear mRNA branch site recognition http://purl.obolibrary.org/obo/GO_0000348 GO:0000354 biolink:BiologicalProcess cis assembly of pre-catalytic spliceosome Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. go-plus.json spliceosomal B1 complex formation|cis assembly of U12-type pre-catalytic spliceosome|formation of spliceosomal A2-1 complex|formation of spliceosomal B1 complex|cis assembly of U2-type pre-catalytic spliceosome|spliceosomal B1 complex biosynthesis|spliceosomal A2-1 complex biosynthesis|spliceosomal A2-1 complex formation http://purl.obolibrary.org/obo/GO_0000354 GO:0000353 biolink:BiologicalProcess formation of quadruple SL/U4/U5/U6 snRNP Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000353 GO:0097301 biolink:BiologicalProcess regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter|cellular potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0097301 GO:0000352 biolink:BiologicalProcess trans assembly of SL-containing precatalytic spliceosome Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA. go-plus.json trans assembly of spliced leader-containing precatalytic spliceosome http://purl.obolibrary.org/obo/GO_0000352 GO:0097300 biolink:BiologicalProcess programmed necrotic cell death A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. go-plus.json programmed cell death by necrosis|regulated necrosis http://purl.obolibrary.org/obo/GO_0097300 GO:0000351 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000351 GO:0000358 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000358 GO:0000357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000357 GO:0000356 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000356 GO:0000355 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000355 GO:0000350 biolink:BiologicalProcess generation of catalytic spliceosome for second transesterification step Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. go-plus.json formation of spliceosomal A2-2 complex|formation of catalytic U2-type spliceosome for second transesterification step|formation of spliceosomal C1 complex|spliceosomal C2 complex biosynthesis|lariat formation, 5'-splice site cleavage|spliceosomal A2-3 complex formation|spliceosomal A2-3 complex biosynthesis|catalytic spliceosome assembly for second transesterification step|formation of catalytic spliceosome for second transesterification step|formation of catalytic U12-type spliceosome for second transesterification step|spliceosomal C2 complex formation http://purl.obolibrary.org/obo/GO_0000350 GO:0097307 biolink:BiologicalProcess response to farnesol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097307 GO:0097306 biolink:BiologicalProcess cellular response to alcohol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097306 GO:0097309 biolink:BiologicalProcess cap1 mRNA methylation Methylation of the ribose of the first nucleotide of a 5'-capped mRNA. go-plus.json cap1 mRNA capping http://purl.obolibrary.org/obo/GO_0097309 GO:0000359 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000359 GO:0097308 biolink:BiologicalProcess cellular response to farnesol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097308 GO:0097303 biolink:BiologicalProcess lipoprotein biosynthetic process via N-acyl transfer The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex. go-plus.json lipoprotein biosynthesis (N-acyl transfer) http://purl.obolibrary.org/obo/GO_0097303 GO:0097302 biolink:BiologicalProcess lipoprotein biosynthetic process via diacylglyceryl transfer The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex. go-plus.json lipoprotein biosynthesis (diacylglyceryl transfer) http://purl.obolibrary.org/obo/GO_0097302 GO:0097305 biolink:BiologicalProcess response to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. go-plus.json process resulting in tolerance to alcohol http://purl.obolibrary.org/obo/GO_0097305 GO:0097304 biolink:BiologicalProcess lipoprotein biosynthetic process via signal peptide cleavage The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex. go-plus.json lipoprotein biosynthesis (signal peptide cleavage) http://purl.obolibrary.org/obo/GO_0097304 CHEBI:73258 biolink:ChemicalSubstance gibberellin A34(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73258 chebi_ph7_3 CHEBI:73257 biolink:ChemicalSubstance gibberellin A20 methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73257 chebi_ph7_3 CHEBI:73259 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73259 UBERON:0035165 biolink:AnatomicalEntity posterior surface of prostate The flattened aspect of the prostate with a slight furrow facing the rectum and anus. go-plus.json posterior surface of prostate gland|facies posterior (prostatae)|facies posterior prostatae http://purl.obolibrary.org/obo/UBERON_0035165 UBERON:0011198 biolink:AnatomicalEntity muscle layer of large intestine A muscle layer that is part of a large intestine. go-plus.json tunica muscularis intestini crassi|muscularis externa of large intestine|muscular layer of large intestine|muscular coat of large intestine http://purl.obolibrary.org/obo/UBERON_0011198 UBERON:0011197 biolink:AnatomicalEntity parathyroid epithelium An epithelium that is part of a parathyroid gland. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011197 CL:0001055 biolink:Cell CD14-positive, CD16-low monocyte An intermediate monocyte that is CD14-positive and with low amounts of CD16. go-plus.json intermediate monocyte, human http://purl.obolibrary.org/obo/CL_0001055 CL:0001054 biolink:Cell CD14-positive monocyte A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. go-plus.json monocyte http://purl.obolibrary.org/obo/CL_0001054 CHEBI:38920 biolink:ChemicalSubstance benzochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38920 PR:000001661 biolink:Protein proteinase-activated receptor 1 A proteinase-activated receptor that is a translation product of the human F2R gene or a 1:1 ortholog thereof. It is activated by thrombin, which cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity. go-plus.json coagulation factor II receptor|CF2R|TR|thrombin receptor|PAR1|F2R|PAR-1 http://purl.obolibrary.org/obo/PR_000001661 PR:000001660 biolink:Protein prostaglandin F2-alpha receptor A prostanoid receptor that is a translation product of the human PTGFR gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin F2a. This receptor is particularly prevalent in the corpus luteum, but is expressed in other tissues also. go-plus.json prostanoid FP receptor|PTGFR|PGF receptor|PGF2-alpha receptor http://purl.obolibrary.org/obo/PR_000001660 CL:0001059 biolink:Cell common myeloid progenitor, CD34-positive A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. go-plus.json common myeloid precursor, CD34-positive|CFU-GEMM|CFU-S|pluripotent stem cell (bone marrow)|multipotential myeloid stem cell|myeloid stem cell|CMP|colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte http://purl.obolibrary.org/obo/CL_0001059 CHEBI:38925 biolink:ChemicalSubstance benzopteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38925 CHEBI:38922 biolink:ChemicalSubstance dibenzofurans go-plus.json http://purl.obolibrary.org/obo/CHEBI_38922 CHEBI:73250 biolink:ChemicalSubstance gibberellin A1 methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73250 chebi_ph7_3 CHEBI:73252 biolink:ChemicalSubstance gibberellin A4 methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73252 chebi_ph7_3 CHEBI:73251 biolink:ChemicalSubstance gibberellin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73251 chebi_ph7_3 CL:0001051 biolink:Cell CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. go-plus.json CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte|CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell|non-Th1/Th17 CD4+ T cell|CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/CL_0001051 CHEBI:73254 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73254 CL:0001050 biolink:Cell effector CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. go-plus.json effector CD8-positive, alpha-beta T-cell|effector CD8-positive, alpha-beta T-lymphocyte|effector CD8+ T cell|effector CD8-positive, alpha-beta T lymphocyte http://purl.obolibrary.org/obo/CL_0001050 CHEBI:73253 biolink:ChemicalSubstance gibberellin A3 methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73253 chebi_ph7_3 CL:0001053 biolink:Cell IgD-negative memory B cell A memory B cell that lacks expression of surface IgD. go-plus.json IgD- memory B cell http://purl.obolibrary.org/obo/CL_0001053 CHEBI:73256 biolink:ChemicalSubstance gibberellin A9 methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73256 chebi_ph7_3 CL:0001052 biolink:Cell CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. go-plus.json non-Tc1/Tc17 CD8+ T cell|CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte|CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte|CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell http://purl.obolibrary.org/obo/CL_0001052 CHEBI:73255 biolink:ChemicalSubstance gibberellin A9(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73255 chebi_ph7_3 CHEBI:73268 biolink:ChemicalSubstance gibberellin ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73268 UBERON:0035174 biolink:AnatomicalEntity right ear The organ of hearing located on the right side of the head. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035174 UBERON:0011185 biolink:AnatomicalEntity gastrointestinal sphincter A sphincter muscle that is part of the gastrointestinal system go-plus.json http://purl.obolibrary.org/obo/UBERON_0011185 CHEBI:14949 biolink:ChemicalSubstance N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_14949 UBERON:0011189 biolink:AnatomicalEntity lamina propria of large intestine A lamina propria that is part of a large intestine. go-plus.json large intestine lamina propria|lamina propria of mucosa of large intestine|large intestinal lamina propria http://purl.obolibrary.org/obo/UBERON_0011189 CL:0001066 biolink:Cell erythroid progenitor cell, mammalian A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). go-plus.json blast forming unit erythroid|colony forming unit erythroid|burst forming unit erythroid|erythroid stem cell|CFU-E|BFU-E http://purl.obolibrary.org/obo/CL_0001066 CHEBI:38932 biolink:ChemicalSubstance pyridopyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38932 CL:0001065 biolink:Cell innate lymphoid cell A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. go-plus.json http://purl.obolibrary.org/obo/CL_0001065 CL:0001068 biolink:Cell ILC1 A group 1 innate lymphoid cell that is non-cytotoxic. go-plus.json http://purl.obolibrary.org/obo/CL_0001068 CL:0001067 biolink:Cell group 1 innate lymphoid cell An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines. go-plus.json http://purl.obolibrary.org/obo/CL_0001067 CL:0001069 biolink:Cell group 2 innate lymphoid cell An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation. go-plus.json natural helper cell|ILC2|nuocyte http://purl.obolibrary.org/obo/CL_0001069 PR:000001676 biolink:Protein thromboxane A2 receptor A prostanoid receptor that is a translation product of the human TBXA2R gene or a 1:1 ortholog thereof. The preferred ligand is thromboxane A2. This receptor is found mainly in vascular smooth muscle, where it mediates vasoconstriction, in platelets, where it mediates aggregation, and in airway smooth muscle. go-plus.json prostanoid TP receptor|TXA2-R|TBXA2R http://purl.obolibrary.org/obo/PR_000001676 CHEBI:38934 biolink:ChemicalSubstance purvalanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38934 CHEBI:38933 biolink:ChemicalSubstance 3-aminopropane-1-thiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38933 CHEBI:73260 biolink:ChemicalSubstance gibberellin A34 methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_73260 chebi_ph7_3 CL:0001060 biolink:Cell hematopoietic oligopotent progenitor cell, lineage-negative A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. go-plus.json http://purl.obolibrary.org/obo/CL_0001060 CHEBI:73263 biolink:ChemicalSubstance cyclooxygenase 3 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73263 CHEBI:73262 biolink:ChemicalSubstance 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73262 CHEBI:73265 biolink:ChemicalSubstance archaeosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73265 CHEBI:73264 biolink:ChemicalSubstance 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73264 CHEBI:73267 biolink:ChemicalSubstance oxidative phosphorylation inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73267 UBERON:0011171 biolink:AnatomicalEntity joint connecting upper and lower jaws Synovial joint that articulates bones of upper and lower jaw. go-plus.json jaw joint|craniomandibular joint http://purl.obolibrary.org/obo/UBERON_0011171 CL:0001033 biolink:Cell hippocampal granule cell Granule cell that is part of the hippocampus. go-plus.json http://purl.obolibrary.org/obo/CL_0001033 CL:0001032 biolink:Cell cortical granule cell Granule cell that is part of the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/CL_0001032 CL:0001035 biolink:Cell bone cell A connective tissue cell found in bone. go-plus.json http://purl.obolibrary.org/obo/CL_0001035 CHEBI:14973 biolink:ChemicalSubstance pyrazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_14973 CHEBI:73271 biolink:ChemicalSubstance archaeosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73271 CL:0001031 biolink:Cell cerebellar granule cell Granule cell that is part of the cerebellum. go-plus.json http://purl.obolibrary.org/obo/CL_0001031 SO:0000577 biolink:SequenceFeature centromere A region of chromosome where the spindle fibers attach during mitosis and meiosis. http://en.wikipedia.org/wiki/Centromere go-plus.json INSDC_feature:centromere http://purl.obolibrary.org/obo/SO_0000577 SOFA CL:0001030 biolink:Cell CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor go-plus.json http://purl.obolibrary.org/obo/CL_0001030 UBERON:0011160 biolink:AnatomicalEntity nasal suture A suture joining a nasal bone to another bone. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011160 UBERON:0035198 biolink:AnatomicalEntity superficial lymphatic vessel The tubules that carry lymph throughout the body that are just beneath the surface of the skin. go-plus.json superficial lymph vessel http://purl.obolibrary.org/obo/UBERON_0035198 UBERON:0011164 biolink:AnatomicalEntity neurocranium bone A bone that is part of a neurocranium [Automatically generated definition]. go-plus.json chondrocranium bone http://purl.obolibrary.org/obo/UBERON_0011164 CL:0001044 biolink:Cell effector CD4-positive, alpha-beta T cell A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. go-plus.json effector CD4-positive, alpha-beta T-lymphocyte|effector CD4+ T cell|effector CD4-positive, alpha-beta T lymphocyte|effector CD4-positive, alpha-beta T-cell http://purl.obolibrary.org/obo/CL_0001044 CHEBI:73281 biolink:ChemicalSubstance (2S)-versicolorone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73281 chebi_ph7_3 PR:000001656 biolink:Protein prostaglandin D2 receptor A prostanoid receptor that is a translation product of the human PTGDR gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin D2 (PGD2). This receptor is found mainly in blood platelets, vascular smooth muscle, and nervous tissue. It is the least upiquitous of the prostanoid receptors, almost always occurring in association with other prostanoid receptor types. go-plus.json PGD2 receptor|PTGDR|PGD receptor|prostanoid DP receptor http://purl.obolibrary.org/obo/PR_000001656 PR:000001655 biolink:Protein prostacyclin receptor A prostanoid receptor that is a translation product of the human PTGIR gene or a 1:1 ortholog thereof. The preferred ligand is prostacyclin (prostaglandin I2, PGI2). This receptor is widely distributed in blood platelets, vascular smooth muscle and nerve cells. go-plus.json PTGIR|PGI receptor|prostanoid IP receptor|PRIPR|PGI2 receptor|prostaglandin I2 receptor http://purl.obolibrary.org/obo/PR_000001655 PR:000001658 biolink:Protein prostaglandin E2 receptor EP2 subtype A prostanoid receptor that is a translation product of the human PTGER2 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is expressed mediates various effects, including relaxation of vascular smooth muscles, nonacid secretion from epithelial cells, inhibition of mediator release from mast cells and basophils, and activation of sensory afferent nerves. go-plus.json Ptgerep2|PGE receptor EP2 subtype|prostanoid EP2 receptor|PTGER2|prostaglandin E2 receptor EP2|PGE2 receptor EP2 subtype http://purl.obolibrary.org/obo/PR_000001658 PR:000001657 biolink:Protein prostaglandin E2 receptor EP1 subtype A prostanoid receptor that is a translation product of the human PTGER1 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor has limited expression, although it is more evident in rodents than in other mammals. go-plus.json Ptgerep1|PGE receptor EP1 subtype|prostanoid EP1 receptor|PTGER1|prostaglandin E2 receptor EP1|PGE2 receptor EP1 subtype http://purl.obolibrary.org/obo/PR_000001657 PR:000001659 biolink:Protein prostaglandin E2 receptor EP3 subtype A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney. go-plus.json Ptgerep3|PGE receptor EP3 subtype|PGE2-R|prostanoid EP3 receptor|PTGER3|prostaglandin E2 receptor EP3|PGE2 receptor EP3 subtype http://purl.obolibrary.org/obo/PR_000001659 CL:0001042 biolink:Cell T-helper 22 cell CD4-positive, alpha-beta T cell that produces IL-22. go-plus.json Th22 T-lymphocyte|Th22 T cell|Th22 T lymphocyte|Th22 cell|T(H)-22 cell|Th22 T-cell|helper T cell type 22 http://purl.obolibrary.org/obo/CL_0001042 CL:0001041 biolink:Cell CD8-positive, CXCR3-positive, alpha-beta regulatory T cell A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. go-plus.json CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte|CD8+CXCR3+ T cell|CD8+CXCR3+ T lymphocyte|CD8+CXCR3+ T(reg)|CD8-positive, CXCR3-positive, T(reg)|CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell|CD8+CXCR3+ Treg|CD8-positive, CXCR3-positive, Treg|CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte|CD8+CXCR3+ T-cell http://purl.obolibrary.org/obo/CL_0001041 GO:1903709 biolink:BiologicalProcess uterine gland development The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure. go-plus.json set of uterine glands development|glandular part of endometrium development|uterine glands set development|uterine glands development|endometrium gland development|glandulae uterinae development|endometrial gland development http://purl.obolibrary.org/obo/GO_1903709 GO:1903708 biolink:BiologicalProcess positive regulation of hemopoiesis Any process that activates or increases the frequency, rate or extent of hemopoiesis. go-plus.json positive regulation of haemopoiesis|up regulation of haemopoiesis|up regulation of blood cell biosynthesis|up regulation of hemopoiesis|positive regulation of blood cell biosynthesis|activation of blood cell biosynthesis|activation of hemopoiesis|upregulation of hematopoiesis|upregulation of blood cell formation|upregulation of haemopoiesis|up-regulation of blood cell biosynthesis|up regulation of hematopoiesis|up-regulation of hemopoiesis|up-regulation of blood cell formation|activation of blood cell formation|activation of hematopoiesis|positive regulation of hematopoiesis|up-regulation of haemopoiesis|activation of haemopoiesis|upregulation of blood cell biosynthesis|upregulation of hemopoiesis|positive regulation of blood cell formation|up-regulation of hematopoiesis|up regulation of blood cell formation http://purl.obolibrary.org/obo/GO_1903708 GO:1903707 biolink:BiologicalProcess negative regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. go-plus.json downregulation of blood cell formation|downregulation of hemopoiesis|down regulation of blood cell formation|downregulation of haemopoiesis|inhibition of blood cell formation|down-regulation of blood cell biosynthesis|negative regulation of blood cell biosynthesis|down-regulation of hemopoiesis|down regulation of hematopoiesis|down regulation of haemopoiesis|inhibition of haemopoiesis|downregulation of hematopoiesis|inhibition of blood cell biosynthesis|inhibition of hemopoiesis|down-regulation of hematopoiesis|negative regulation of hematopoiesis|down-regulation of blood cell formation|negative regulation of blood cell formation|down regulation of blood cell biosynthesis|down-regulation of haemopoiesis|down regulation of hemopoiesis|negative regulation of haemopoiesis|inhibition of hematopoiesis|downregulation of blood cell biosynthesis http://purl.obolibrary.org/obo/GO_1903707 NCBITaxon:2711 biolink:OrganismalEntity Citrus sinensis go-plus.json navel orange|naranja|Citrus x sinensis|sweet orange|Valencia orange|apfelsine http://purl.obolibrary.org/obo/NCBITaxon_2711 GO:1903706 biolink:BiologicalProcess regulation of hemopoiesis Any process that modulates the frequency, rate or extent of hemopoiesis. go-plus.json regulation of blood cell formation|regulation of haemopoiesis|regulation of hematopoiesis|regulation of blood cell biosynthesis http://purl.obolibrary.org/obo/GO_1903706 GO:1903705 biolink:BiologicalProcess positive regulation of production of siRNA involved in RNA interference Any process that activates or increases the frequency, rate or extent of production of siRNA involved in RNA interference. go-plus.json up-regulation of RNA interference, production of guide RNAs|up regulation of production of siRNA involved in RNA interference|activation of RNA interference, production of guide RNAs|up-regulation of production of guide RNAs involved in RNA interference|up regulation of RNA interference, production of siRNA|positive regulation of RNA interference, production of siRNA|activation of RNA interference, production of siRNA|upregulation of production of siRNA involved in RNA interference|positive regulation of RNA interference, production of guide RNAs|upregulation of production of guide RNAs involved in RNA interference|up regulation of RNA interference, production of guide RNAs|up-regulation of RNA interference, production of siRNA|up-regulation of production of siRNA involved in RNA interference|activation of production of siRNA involved in RNA interference|upregulation of RNA interference, production of guide RNAs|up regulation of production of guide RNAs involved in RNA interference|positive regulation of production of guide RNAs involved in RNA interference|activation of production of guide RNAs involved in RNA interference|upregulation of RNA interference, production of siRNA http://purl.obolibrary.org/obo/GO_1903705 GO:1903704 biolink:BiologicalProcess negative regulation of production of siRNA involved in RNA interference Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference. go-plus.json negative regulation of production of guide RNAs involved in RNA interference|down-regulation of production of guide RNAs involved in RNA interference|down regulation of RNA interference, production of siRNA|downregulation of RNA interference, production of siRNA|inhibition of production of guide RNAs involved in RNA interference|downregulation of production of siRNA involved in RNA interference|down-regulation of RNA interference, production of guide RNAs|down regulation of production of siRNA involved in RNA interference|negative regulation of RNA interference, production of guide RNAs|inhibition of production of siRNA involved in RNA interference|negative regulation of RNA interference, production of siRNA|down-regulation of RNA interference, production of siRNA|downregulation of RNA interference, production of guide RNAs|down regulation of production of guide RNAs involved in RNA interference|inhibition of RNA interference, production of siRNA|down regulation of RNA interference, production of guide RNAs|downregulation of production of guide RNAs involved in RNA interference|inhibition of RNA interference, production of guide RNAs|down-regulation of production of siRNA involved in RNA interference http://purl.obolibrary.org/obo/GO_1903704 GO:1903703 biolink:BiologicalProcess enterocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte. go-plus.json http://purl.obolibrary.org/obo/GO_1903703 GO:1903702 biolink:BiologicalProcess esophagus development The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. go-plus.json oesophagus development|esophageal development|gullet development http://purl.obolibrary.org/obo/GO_1903702 GO:0048307 biolink:MolecularActivity ferredoxin-nitrite reductase activity Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+. MetaCyc:FERREDOXIN--NITRITE-REDUCTASE-RXN|EC:1.7.7.1|RHEA:18041 go-plus.json ammonia:ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0048307 CL:0001019 biolink:Cell CD115-positive monocyte OR common dendritic progenitor go-plus.json http://purl.obolibrary.org/obo/CL_0001019 GO:1903701 biolink:BiologicalProcess substantia propria of cornea development The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. go-plus.json corneal stroma development|substantia propria development|stroma of cornea development http://purl.obolibrary.org/obo/GO_1903701 GO:0048306 biolink:MolecularActivity calcium-dependent protein binding Binding to a protein or protein complex in the presence of calcium. go-plus.json http://purl.obolibrary.org/obo/GO_0048306 GO:1903700 biolink:BiologicalProcess caecum development The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure. go-plus.json blindgut development|caeca development|ceca development|intestinum caecum development|cecum development|blind intestine development|intestinum crassum caecum development|intestinum crassum cecum development http://purl.obolibrary.org/obo/GO_1903700 GO:0048305 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048305 GO:0048304 biolink:BiologicalProcess positive regulation of isotype switching to IgG isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes. go-plus.json positive regulation of class switching to IgG isotypes|positive regulation of isotype switch recombination to IgG isotypes|up-regulation of isotype switching to IgG isotypes|upregulation of isotype switching to IgG isotypes|up regulation of isotype switching to IgG isotypes|activation of isotype switching to IgG isotypes|positive regulation of class switch recombination to IgG isotypes|stimulation of isotype switching to IgG isotypes http://purl.obolibrary.org/obo/GO_0048304 CHEBI:14919 biolink:ChemicalSubstance N(6)-lipoyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_14919 GO:0048303 biolink:BiologicalProcess negative regulation of isotype switching to IgG isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes. go-plus.json inhibition of isotype switching to IgG isotypes|negative regulation of class switching to IgG isotypes|down regulation of isotype switching to IgG isotypes|downregulation of isotype switching to IgG isotypes|negative regulation of class switch recombination to IgG isotypes|down-regulation of isotype switching to IgG isotypes|negative regulation of isotype switch recombination to IgG isotypes http://purl.obolibrary.org/obo/GO_0048303 GO:0048302 biolink:BiologicalProcess regulation of isotype switching to IgG isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes. go-plus.json regulation of class switch recombination to IgG isotypes|regulation of isotype switch recombination to IgG isotypes|regulation of class switching to IgG isotypes http://purl.obolibrary.org/obo/GO_0048302 NCBITaxon:2713 biolink:OrganismalEntity Aquifex go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2713 GO:0048301 biolink:BiologicalProcess positive regulation of isotype switching to IgD isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes. go-plus.json up-regulation of isotype switching to IgD isotypes|upregulation of isotype switching to IgD isotypes|up regulation of isotype switching to IgD isotypes|activation of isotype switching to IgD isotypes|positive regulation of class switch recombination to IgD isotypes|stimulation of isotype switching to IgD isotypes|positive regulation of class switching to IgD isotypes|positive regulation of isotype switch recombination to IgD isotypes http://purl.obolibrary.org/obo/GO_0048301 UBERON:0035128 biolink:AnatomicalEntity manus cartilage element go-plus.json hand cartilage condensation http://purl.obolibrary.org/obo/UBERON_0035128 GO:0048300 biolink:BiologicalProcess negative regulation of isotype switching to IgD isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes. go-plus.json negative regulation of class switching to IgD isotypes|down regulation of isotype switching to IgD isotypes|downregulation of isotype switching to IgD isotypes|negative regulation of class switch recombination to IgD isotypes|down-regulation of isotype switching to IgD isotypes|negative regulation of isotype switch recombination to IgD isotypes|inhibition of isotype switching to IgD isotypes http://purl.obolibrary.org/obo/GO_0048300 UBERON:0035127 biolink:AnatomicalEntity suture of hard palate Any of the sutures of the hard palate go-plus.json palatine suture http://purl.obolibrary.org/obo/UBERON_0035127 UBERON:0035118 biolink:AnatomicalEntity material entity in digestive tract Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included. go-plus.json ingested material entity|digestive tract contents http://purl.obolibrary.org/obo/UBERON_0035118 CL:0001012 biolink:Cell CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor go-plus.json http://purl.obolibrary.org/obo/CL_0001012 GO:0048309 biolink:BiologicalProcess endoplasmic reticulum inheritance The partitioning of endoplasmic reticulum between daughter cells at cell division. go-plus.json ER inheritance http://purl.obolibrary.org/obo/GO_0048309 GO:0048308 biolink:BiologicalProcess organelle inheritance The partitioning of organelles between daughter cells at cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0048308 goslim_yeast|goslim_pir CHEBI:73296 biolink:ChemicalSubstance cholecystokinin antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_73296 CHEBI:73299 biolink:ChemicalSubstance cobalt(II)-factor III(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73299 chebi_ph7_3 GO:0048310 biolink:BiologicalProcess obsolete nucleus inheritance OBSOLETE. The partitioning of nuclei between daughter cells at cell division. go-plus.json cell nucleus inheritance http://purl.obolibrary.org/obo/GO_0048310 SO:0000594 biolink:SequenceFeature H_ACA_box_snoRNA Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains. go-plus.json H/ACA box snoRNA|box H/ACA snoRNA|H ACA box snoRNA http://purl.obolibrary.org/obo/SO_0000594 SO:0000593 biolink:SequenceFeature C_D_box_snoRNA Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'. go-plus.json C/D box snoRNA|box C/D snoRNA|C D box snoRNA http://purl.obolibrary.org/obo/SO_0000593 SOFA GO:1903719 biolink:BiologicalProcess regulation of I-kappaB phosphorylation Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation. go-plus.json regulation of IKB phosphorylation|regulation of IkappaB phosphorylation|regulation of inhibitor of NF-kappaB phosphorylation|regulation of inhibitor of kappaB phosphorylation http://purl.obolibrary.org/obo/GO_1903719 GO:1903718 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903718 GO:1903717 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903717 GO:1903716 biolink:BiologicalProcess guanine transmembrane transport The process in which guanine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903716 GO:1903715 biolink:BiologicalProcess regulation of aerobic respiration Any process that modulates the frequency, rate or extent of aerobic respiration. go-plus.json http://purl.obolibrary.org/obo/GO_1903715 UBERON:0035131 biolink:AnatomicalEntity auditory ossicle cartilage element go-plus.json ossicle cartilage condensation http://purl.obolibrary.org/obo/UBERON_0035131 UBERON:0035130 biolink:AnatomicalEntity auditory ossicle endochondral element go-plus.json auditory skeletal element|ossicle element|ear ossicles element|ear ossicle element|ossicle element of ear|middle ear ossicle element|ossicular chain element|middle ear skeletal element|ossicle element of inner ear http://purl.obolibrary.org/obo/UBERON_0035130 GO:1903714 biolink:BiologicalProcess isoleucine transmembrane transport The directed movement of isoleucine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903714 GO:0048318 biolink:BiologicalProcess axial mesoderm development The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. go-plus.json http://purl.obolibrary.org/obo/GO_0048318 GO:1903713 biolink:BiologicalProcess asparagine transmembrane transport The directed movement of asparagine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903713 UBERON:0035132 biolink:AnatomicalEntity auditory ossicle pre-cartilage element go-plus.json ossicle pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0035132 CL:0001029 biolink:Cell common dendritic progenitor Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. go-plus.json common dendritic precursor|pro-DCs|CDP http://purl.obolibrary.org/obo/CL_0001029 GO:1903712 biolink:BiologicalProcess cysteine transmembrane transport The directed movement of cysteine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903712 GO:0048317 biolink:BiologicalProcess seed morphogenesis The process in which the anatomical structures of the seed are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048317 GO:0048316 biolink:BiologicalProcess seed development The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves. go-plus.json http://purl.obolibrary.org/obo/GO_0048316 GO:1903711 biolink:BiologicalProcess spermidine transmembrane transport The process in which spermidine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903711 GO:0048315 biolink:BiologicalProcess conidium formation The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. go-plus.json conidia formation|conidia biosynthesis http://purl.obolibrary.org/obo/GO_0048315 GO:1903710 biolink:BiologicalProcess spermine transmembrane transport The process in which spermine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903710 GO:0048314 biolink:BiologicalProcess embryo sac morphogenesis The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants. go-plus.json female gametophyte morphogenesis http://purl.obolibrary.org/obo/GO_0048314 GO:0048313 biolink:BiologicalProcess Golgi inheritance The partitioning of Golgi apparatus between daughter cells at cell division. go-plus.json Golgi division|Golgi partitioning http://purl.obolibrary.org/obo/GO_0048313 GO:0048312 biolink:BiologicalProcess intracellular distribution of mitochondria Any process that establishes the spatial arrangement of mitochondria within the cell. go-plus.json mitochondria positioning within cell|mitochondrion positioning within cell http://purl.obolibrary.org/obo/GO_0048312 GO:0048311 biolink:BiologicalProcess mitochondrion distribution Any process that establishes the spatial arrangement of mitochondria between and within cells. go-plus.json positioning of mitochondria|mitochondrial distribution|distribution of mitochondria http://purl.obolibrary.org/obo/GO_0048311 CL:0001022 biolink:Cell CD115-positive monocyte CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0001022 UBERON:0035129 biolink:AnatomicalEntity pes cartilage element go-plus.json foot cartilage condensation http://purl.obolibrary.org/obo/UBERON_0035129 CL:0001021 biolink:Cell CD34-positive, CD38-positive common lymphoid progenitor A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. go-plus.json CD10-positive common lymphoid precursor|CD10-positive common lymphocyte progenitor|CD10-positive common lymphocyte precursor http://purl.obolibrary.org/obo/CL_0001021 CL:0001024 biolink:Cell CD34-positive, CD38-negative hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. go-plus.json CD133-positive hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0001024 CL:0001023 biolink:Cell Kit-positive, CD34-positive common myeloid progenitor A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low. go-plus.json CD117-positive common myeloid precursor http://purl.obolibrary.org/obo/CL_0001023 CL:0001026 biolink:Cell CD34-positive, CD38-positive common myeloid progenitor A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. go-plus.json CD71-positive common myeloid precursor http://purl.obolibrary.org/obo/CL_0001026 CL:0001025 biolink:Cell Kit-positive, Sca1-positive common lymphoid progenitor A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low. go-plus.json CD217-positive common lymphocyte precursor|CD217-positive common lymphoid precursor|CD217-positive common lymphocyte progenitor http://purl.obolibrary.org/obo/CL_0001025 CL:0001028 biolink:Cell CD7-positive lymphoid progenitor cell CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. go-plus.json CD7-positive lymphoid precursor http://purl.obolibrary.org/obo/CL_0001028 CL:0001027 biolink:Cell CD7-negative lymphoid progenitor cell CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. go-plus.json CD7-negative lymphoid precursor http://purl.obolibrary.org/obo/CL_0001027 GO:0048319 biolink:BiologicalProcess axial mesoderm morphogenesis The process in which the anatomical structures of the axial mesoderm are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048319 SO:0000587 biolink:SequenceFeature group_I_intron Group I catalytic introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of 9 paired regions (P1-P9). These fold to essentially two domains, the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). Group I catalytic introns often have long ORFs inserted in loop regions. http://en.wikipedia.org/wiki/Group_I_intron go-plus.json group I intron http://purl.obolibrary.org/obo/SO_0000587 SOFA SO:0000588 biolink:SequenceFeature autocatalytically_spliced_intron A self spliced intron. go-plus.json autocatalytically spliced intron|INSDC_qualifier:autocatalytically_spliced_intron|INSDC_feature:ncRNA http://purl.obolibrary.org/obo/SO_0000588 SOFA GO:0048321 biolink:BiologicalProcess axial mesodermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell. go-plus.json axial mesoderm cell differentiation http://purl.obolibrary.org/obo/GO_0048321 GO:0048320 biolink:BiologicalProcess axial mesoderm formation The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048320 GO:1903729 biolink:BiologicalProcess regulation of plasma membrane organization Any process that modulates the frequency, rate or extent of plasma membrane organization. go-plus.json regulation of plasma membrane organisation|regulation of plasma membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_1903729 GO:1903728 biolink:BiologicalProcess luteal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells. go-plus.json lutein cell differentiation http://purl.obolibrary.org/obo/GO_1903728 GO:1903727 biolink:BiologicalProcess positive regulation of phospholipid metabolic process Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process. go-plus.json upregulation of phospholipid metabolism|upregulation of phospholipid metabolic process|up regulation of phospholipid metabolism|activation of phospholipid metabolism|positive regulation of phospholipid metabolism|up-regulation of phospholipid metabolic process|activation of phospholipid metabolic process|up-regulation of phospholipid metabolism|up regulation of phospholipid metabolic process http://purl.obolibrary.org/obo/GO_1903727 GO:1903726 biolink:BiologicalProcess negative regulation of phospholipid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process. go-plus.json down regulation of phospholipid metabolic process|inhibition of phospholipid metabolic process|down regulation of phospholipid metabolism|downregulation of phospholipid metabolism|negative regulation of phospholipid metabolism|down-regulation of phospholipid metabolism|down-regulation of phospholipid metabolic process|inhibition of phospholipid metabolism|downregulation of phospholipid metabolic process http://purl.obolibrary.org/obo/GO_1903726 GO:1903725 biolink:BiologicalProcess regulation of phospholipid metabolic process Any process that modulates the frequency, rate or extent of phospholipid metabolic process. go-plus.json regulation of phospholipid metabolism http://purl.obolibrary.org/obo/GO_1903725 GO:0048329 biolink:BiologicalProcess negative regulation of axial mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification. go-plus.json inhibition of axial mesodermal cell fate specification|down-regulation of axial mesodermal cell fate specification|downregulation of axial mesodermal cell fate specification|down regulation of axial mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048329 GO:1903724 biolink:BiologicalProcess positive regulation of centriole elongation Any process that activates or increases the frequency, rate or extent of centriole elongation. go-plus.json up regulation of centriole elongation|upregulation of centriole elongation|activation of centriole elongation|up-regulation of centriole elongation http://purl.obolibrary.org/obo/GO_1903724 GO:1903723 biolink:BiologicalProcess negative regulation of centriole elongation Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation. go-plus.json downregulation of centriole elongation|down regulation of centriole elongation|inhibition of centriole elongation|down-regulation of centriole elongation http://purl.obolibrary.org/obo/GO_1903723 GO:0048328 biolink:BiologicalProcess regulation of axial mesodermal cell fate specification Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0048328 CHEBI:167457 biolink:ChemicalSubstance poly[(R)-3-hydroxyalkanoate] go-plus.json http://purl.obolibrary.org/obo/CHEBI_167457 GO:1903722 biolink:BiologicalProcess regulation of centriole elongation Any process that modulates the frequency, rate or extent of centriole elongation. go-plus.json http://purl.obolibrary.org/obo/GO_1903722 GO:0048327 biolink:BiologicalProcess axial mesodermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json axial mesoderm cell fate specification http://purl.obolibrary.org/obo/GO_0048327 GO:1903721 biolink:BiologicalProcess positive regulation of I-kappaB phosphorylation Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation. go-plus.json upregulation of inhibitor of kappaB phosphorylation|up-regulation of IkappaB phosphorylation|up-regulation of IKB phosphorylation|up regulation of I-kappaB phosphorylation|positive regulation of inhibitor of NF-kappaB phosphorylation|upregulation of IkappaB phosphorylation|upregulation of IKB phosphorylation|up regulation of inhibitor of kappaB phosphorylation|up regulation of inhibitor of NF-kappaB phosphorylation|positive regulation of inhibitor of kappaB phosphorylation|activation of inhibitor of kappaB phosphorylation|upregulation of I-kappaB phosphorylation|up regulation of IKB phosphorylation|up regulation of IkappaB phosphorylation|upregulation of inhibitor of NF-kappaB phosphorylation|activation of IKB phosphorylation|positive regulation of IkappaB phosphorylation|activation of IkappaB phosphorylation|positive regulation of IKB phosphorylation|up-regulation of inhibitor of kappaB phosphorylation|up-regulation of I-kappaB phosphorylation|activation of I-kappaB phosphorylation|up-regulation of inhibitor of NF-kappaB phosphorylation|activation of inhibitor of NF-kappaB phosphorylation http://purl.obolibrary.org/obo/GO_1903721 GO:0048326 biolink:BiologicalProcess positive regulation of axial mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination. go-plus.json upregulation of axial mesodermal cell fate determination|stimulation of axial mesodermal cell fate determination|activation of axial mesodermal cell fate determination|up-regulation of axial mesodermal cell fate determination|up regulation of axial mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048326 GO:1903720 biolink:BiologicalProcess negative regulation of I-kappaB phosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation. go-plus.json inhibition of IKB phosphorylation|inhibition of IkappaB phosphorylation|down regulation of inhibitor of kappaB phosphorylation|down-regulation of I-kappaB phosphorylation|down-regulation of inhibitor of NF-kappaB phosphorylation|negative regulation of inhibitor of NF-kappaB phosphorylation|downregulation of inhibitor of kappaB phosphorylation|downregulation of I-kappaB phosphorylation|down regulation of IKB phosphorylation|down regulation of IkappaB phosphorylation|downregulation of inhibitor of NF-kappaB phosphorylation|down regulation of I-kappaB phosphorylation|negative regulation of inhibitor of kappaB phosphorylation|down-regulation of inhibitor of kappaB phosphorylation|downregulation of IkappaB phosphorylation|downregulation of IKB phosphorylation|inhibition of I-kappaB phosphorylation|down regulation of inhibitor of NF-kappaB phosphorylation|inhibition of inhibitor of NF-kappaB phosphorylation|inhibition of inhibitor of kappaB phosphorylation|negative regulation of IkappaB phosphorylation|down-regulation of IkappaB phosphorylation|negative regulation of IKB phosphorylation|down-regulation of IKB phosphorylation http://purl.obolibrary.org/obo/GO_1903720 GO:0048325 biolink:BiologicalProcess negative regulation of axial mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination. go-plus.json down-regulation of axial mesodermal cell fate determination|downregulation of axial mesodermal cell fate determination|down regulation of axial mesodermal cell fate determination|inhibition of axial mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048325 GO:0048324 biolink:BiologicalProcess regulation of axial mesodermal cell fate determination Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination. go-plus.json http://purl.obolibrary.org/obo/GO_0048324 GO:0048323 biolink:BiologicalProcess axial mesodermal cell fate determination The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json axial mesoderm cell fate determination http://purl.obolibrary.org/obo/GO_0048323 GO:0048322 biolink:BiologicalProcess axial mesodermal cell fate commitment The process in which a cell becomes committed to become an axial mesoderm cell. go-plus.json axial mesoderm cell fate commitment http://purl.obolibrary.org/obo/GO_0048322 GO:0048332 biolink:BiologicalProcess mesoderm morphogenesis The process in which the anatomical structures of the mesoderm are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048332 GO:0048331 biolink:BiologicalProcess axial mesoderm structural organization The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure. go-plus.json axial mesoderm structural organisation http://purl.obolibrary.org/obo/GO_0048331 GO:0048330 biolink:BiologicalProcess positive regulation of axial mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification. go-plus.json up regulation of axial mesodermal cell fate specification|upregulation of axial mesodermal cell fate specification|stimulation of axial mesodermal cell fate specification|up-regulation of axial mesodermal cell fate specification|activation of axial mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048330 CL:0001008 biolink:Cell Kit and Sca1-positive hematopoietic stem cell A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. go-plus.json Sca1-positive hematopoietic stem cell|LSK stem cell http://purl.obolibrary.org/obo/CL_0001008 GO:0048339 biolink:BiologicalProcess paraxial mesoderm development The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0048339 NCBITaxon:2706 biolink:OrganismalEntity Citrus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2706 GO:0048338 biolink:BiologicalProcess mesoderm structural organization The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure. go-plus.json mesoderm structural organisation http://purl.obolibrary.org/obo/GO_0048338 GO:0048337 biolink:BiologicalProcess positive regulation of mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification. go-plus.json up regulation of mesodermal cell fate specification|upregulation of mesodermal cell fate specification|stimulation of mesodermal cell fate specification|up-regulation of mesodermal cell fate specification|activation of mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048337 UBERON:0035159 biolink:AnatomicalEntity entire surface of organism Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface. go-plus.json surface of body http://purl.obolibrary.org/obo/UBERON_0035159 GO:0048336 biolink:BiologicalProcess positive regulation of mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination. go-plus.json up regulation of mesodermal cell fate determination|upregulation of mesodermal cell fate determination|stimulation of mesodermal cell fate determination|activation of mesodermal cell fate determination|up-regulation of mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048336 GO:1903730 biolink:BiologicalProcess regulation of phosphatidate phosphatase activity Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity. go-plus.json regulation of phosphatidic acid phosphatase activity|regulation of phosphatidate phosphohydrolase activity|regulation of acid phosphatidyl phosphatase activity|regulation of 3-sn-phosphatidate phosphohydrolase activity|regulation of phosphatic acid phosphohydrolase activity|regulation of phosphatic acid phosphatase activity http://purl.obolibrary.org/obo/GO_1903730 GO:0048335 biolink:BiologicalProcess negative regulation of mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination. go-plus.json down-regulation of mesodermal cell fate determination|downregulation of mesodermal cell fate determination|down regulation of mesodermal cell fate determination|inhibition of mesodermal cell fate determination http://purl.obolibrary.org/obo/GO_0048335 GO:0048334 biolink:BiologicalProcess regulation of mesodermal cell fate determination Any process that modulates the frequency, rate or extent of mesoderm cell fate determination. go-plus.json http://purl.obolibrary.org/obo/GO_0048334 GO:0048333 biolink:BiologicalProcess mesodermal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. go-plus.json mesoderm cell differentiation http://purl.obolibrary.org/obo/GO_0048333 NCBITaxon:169963 biolink:OrganismalEntity Listeria monocytogenes EGD-e go-plus.json Listeria monocytogenes str. EGD-e|Listeria monocytogenes strain EGD-e|Listeria monocytogenes EGDe|Listeria monocytogenes ATCC BAA-679 http://purl.obolibrary.org/obo/NCBITaxon_169963 CHEBI:48218 biolink:ChemicalSubstance antiseptic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48218 CHEBI:48219 biolink:ChemicalSubstance disinfectant go-plus.json http://purl.obolibrary.org/obo/CHEBI_48219 CHEBI:48210 biolink:ChemicalSubstance cyclopentafurofurochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48210 UBERON:0011234 biolink:AnatomicalEntity fibrous membrane of synovial tendon sheath go-plus.json http://purl.obolibrary.org/obo/UBERON_0011234 UBERON:0011233 biolink:AnatomicalEntity synovial membrane of synovial tendon sheath Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa. go-plus.json synovium http://purl.obolibrary.org/obo/UBERON_0011233 CHEBI:87824 biolink:ChemicalSubstance methionine sulfone zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_87824 chebi_ph7_3 CHEBI:87826 biolink:ChemicalSubstance L-methionine sulfoximine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_87826 chebi_ph7_3 CHEBI:87825 biolink:ChemicalSubstance N-acetylmethionine sulfone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87825 chebi_ph7_3 CHEBI:87828 biolink:ChemicalSubstance N(6)-glutaryl-L-lysine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87828 chebi_ph7_3 CHEBI:63856 biolink:ChemicalSubstance 4,8-dimethylnonanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63856 CHEBI:87827 biolink:ChemicalSubstance N-acetyl-L-methionine sulfoximine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87827 chebi_ph7_3 CHEBI:87829 biolink:ChemicalSubstance 2''-O-glutaryl-ADP-D-ribose(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87829 chebi_ph7_3 CHEBI:38884 biolink:ChemicalSubstance diphenylmethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38884 chebi_ph7_3 UBERON:0001899 biolink:AnatomicalEntity epithalamus Most dorsal part of the thalamus, comprising the pineal gland and habenular nuclei in most vertebrates. In a few vertebrates, it also includes the parietal eye. (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed, 2005, pg. 345-346. go-plus.json epithalamus|ETh http://purl.obolibrary.org/obo/UBERON_0001899 UBERON:0001898 biolink:AnatomicalEntity hypothalamus A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. go-plus.json Hy|preoptico-hypothalamic region|hypothalamus|preoptico-hypothalamic area http://purl.obolibrary.org/obo/UBERON_0001898 CHEBI:48206 biolink:ChemicalSubstance fucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48206 CHEBI:24250 biolink:ChemicalSubstance gibberellin go-plus.json http://purl.obolibrary.org/obo/CHEBI_24250 CHEBI:63862 biolink:ChemicalSubstance 3'-N-debenzoyltaxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63862 UBERON:0011222 biolink:AnatomicalEntity intra-ocular muscle go-plus.json intrinsic muscle of eyeball|intrinsic ocular muscle http://purl.obolibrary.org/obo/UBERON_0011222 CHEBI:87810 biolink:ChemicalSubstance 3-methylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87810 chebi_ph7_3 CHEBI:63864 biolink:ChemicalSubstance 4,8-dimethylnonanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63864 UBERON:0011216 biolink:AnatomicalEntity organ system subdivision A subdivision of an anatomical system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011216 UBERON:0011215 biolink:AnatomicalEntity central nervous system cell part cluster A multi cell part structure that is part of a central nervous system. go-plus.json cell part cluster of neuraxis|neuraxis layer http://purl.obolibrary.org/obo/UBERON_0011215 CHEBI:63863 biolink:ChemicalSubstance 3'-N-debenzoyltaxol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63863 chebi_ph7_3 CHEBI:87817 biolink:ChemicalSubstance D-ribitol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87817 chebi_ph7_3 CHEBI:63867 biolink:ChemicalSubstance N-(hexanoyl)sphing-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63867 chebi_ph7_3 PR:000001808 biolink:Protein C/C-C motif small inducible chemokine A protein with core architecture consisting of a Small cytokines (intecrine/chemokine), interleukin-8 like (Pfam:PF00048) domain. go-plus.json fam:C/C-C chemokine http://purl.obolibrary.org/obo/PR_000001808 UBERON:0001888 biolink:AnatomicalEntity lateral olfactory stria White matter tract that contains projections from the olfactory bulb to the olfactory cortex (Maryann Martone). go-plus.json olfactory tract|stria olfactoria lateralis|lateral olfactory tract|tractus olfactorius lateralis|LOT|lateral olfactory tract, body|tractus olfactorius lateralis|lateral olfactory stria|lateral olfactory tract. body http://purl.obolibrary.org/obo/UBERON_0001888 CHEBI:24229 biolink:ChemicalSubstance geranylgeraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24229 chebi_ph7_3 UBERON:0001887 biolink:AnatomicalEntity internal capsule of telencephalon White matter regional part of brain which is flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the cerebral cortex and the brainstem and spinal cord. It consists of three distinct parts: an anterior limb, posterior limb, and genu. (Adapted from MSH by Maryann Martone). go-plus.json brain internal capsule|capsula interna|internal capsule radiations|internal capsule http://purl.obolibrary.org/obo/UBERON_0001887 UBERON:0001889 biolink:AnatomicalEntity trunk of phrenic nerve go-plus.json phrenic nerve trunk|phrenic neural trunk http://purl.obolibrary.org/obo/UBERON_0001889 NCBITaxon:131221 biolink:OrganismalEntity Streptophytina go-plus.json Charophyta/Embryophyta group|charophyte/embryophyte group http://purl.obolibrary.org/obo/NCBITaxon_131221 CHEBI:24221 biolink:ChemicalSubstance 3,7-dimethylocta-2,6-dien-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24221 chebi_ph7_3 CHEBI:87840 biolink:ChemicalSubstance cis-3-hydroxy-D-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_87840 chebi_ph7_3 UBERON:0011214 biolink:AnatomicalEntity nucleus of midbrain tectum A neural nucleus that is part of a midbrain tectum. go-plus.json nucleus of tectum|tectal nucleus http://purl.obolibrary.org/obo/UBERON_0011214 UBERON:0011213 biolink:AnatomicalEntity root of vagus nerve A root of cranial nerve that is part of a vagus nerve. go-plus.json vagal root|rX|vagus neural rootlet|vagus root|rootlet of vagus nerve|vagus nerve root http://purl.obolibrary.org/obo/UBERON_0011213 CHEBI:87842 biolink:ChemicalSubstance 1,4-naphthoquinone-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87842 chebi_ph7_3 CHEBI:87841 biolink:ChemicalSubstance 4-pregnen-20,21-diol-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87841 chebi_ph7_3 CHEBI:87844 biolink:ChemicalSubstance 2-phytyl-1,4-dihydroxynaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_87844 chebi_ph7_3 CHEBI:87846 biolink:ChemicalSubstance 3-hydroxy-O,5-dimethyl-L-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_87846 chebi_ph7_3 CHEBI:38863 biolink:ChemicalSubstance trans-decalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38863 chebi_ph7_3 CHEBI:38869 biolink:ChemicalSubstance general anaesthetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_38869 CHEBI:38867 biolink:ChemicalSubstance anaesthetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_38867 UBERON:0001895 biolink:AnatomicalEntity metencephalon Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. go-plus.json epencephalon-2|epencephalon http://purl.obolibrary.org/obo/UBERON_0001895 UBERON:0001894 biolink:AnatomicalEntity diencephalon The division of the forebrain that develops from the foremost primary cerebral vesicle. go-plus.json mature diencephalon|betweenbrain|between brain|interbrain|thalamencephalon|DiE|diencephalon http://purl.obolibrary.org/obo/UBERON_0001894 UBERON:0001897 biolink:AnatomicalEntity dorsal plus ventral thalamus Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87). go-plus.json wider thalamus|Th|thalamus|thalami|thalamencephalon|thalamus opticus http://purl.obolibrary.org/obo/UBERON_0001897 UBERON:0001896 biolink:AnatomicalEntity medulla oblongata Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. go-plus.json bulbus|medulla oblonzata|bulb|metepencephalon|medulla http://purl.obolibrary.org/obo/UBERON_0001896 UBERON:0001891 biolink:AnatomicalEntity midbrain The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. go-plus.json mesencephalon|MB http://purl.obolibrary.org/obo/UBERON_0001891 UBERON:0001890 biolink:AnatomicalEntity forebrain The most anterior region the brain including both the telencephalon and diencephalon. go-plus.json FB|prosencephalon http://purl.obolibrary.org/obo/UBERON_0001890 UBERON:0001893 biolink:AnatomicalEntity telencephalon Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres. go-plus.json cerebrum|endbrain|supratentorial region http://purl.obolibrary.org/obo/UBERON_0001893 UBERON:0001892 biolink:AnatomicalEntity rhombomere A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]. go-plus.json hindbrain segment|hindbrain neuromere|rhombomeres|future rhombencephalon|segment of hindbrain|hindbrain neuromeres|rhombomere http://purl.obolibrary.org/obo/UBERON_0001892 CHEBI:73203 biolink:ChemicalSubstance N-acylsphingosine 1-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73203 chebi_ph7_3 CHEBI:73202 biolink:ChemicalSubstance ceramide phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73202 chebi_ph7_3 CHEBI:73205 biolink:ChemicalSubstance 1,2-palmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73205 IAO:0100001 biolink:OntologyClass term replaced by go-plus.json http://purl.obolibrary.org/obo/IAO_0100001 CHEBI:73204 biolink:ChemicalSubstance ceramide phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73204 CHEBI:24233 biolink:ChemicalSubstance geranylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24233 chebi_ph7_3 CHEBI:73207 biolink:ChemicalSubstance 2-hexadecanoyl-1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73207 UBERON:0001876 biolink:AnatomicalEntity amygdala Subcortical brain region lying anterior to the hippocampal formation in the temporal lobe and anterior to the temporal horn of the lateral ventricle in some species. It is usually subdivided into several groups. Functionally, it is not considered a unitary structure (MM). go-plus.json amygdaloid body|amygdaloid nuclear complex|corpus amygdaloideum|nucleus amygdalae|amygdaloid complex|amygdaloid nucleus|corpus amygdalae|amygdaloid nuclear groups|archistriatum|amygdaloid nuclear group|amygdaloid area http://purl.obolibrary.org/obo/UBERON_0001876 CHEBI:73206 biolink:ChemicalSubstance 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73206 CHEBI:73209 biolink:ChemicalSubstance 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73209 CHEBI:73208 biolink:ChemicalSubstance 2-hexadecanoyl-1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73208 CHEBI:24232 biolink:ChemicalSubstance geranylgeranylglycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24232 UBERON:0011201 biolink:AnatomicalEntity muscle layer of small intestine A muscle layer that is part of a small intestine. go-plus.json muscular coat of small intestine|tunica muscularis intestini tenuis|small intestine muscularis propria|muscularis externa of small intestine|muscular layer of small intestine|tunica muscularis (intestinum tenue) http://purl.obolibrary.org/obo/UBERON_0011201 CHEBI:87831 biolink:ChemicalSubstance N(6)-malonyl-L-lysine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87831 chebi_ph7_3 CHEBI:87830 biolink:ChemicalSubstance N(6)-succinyl-L-lysine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87830 chebi_ph7_3 UBERON:0035237 biolink:AnatomicalEntity branch of internal carotid artery go-plus.json subdivision of internal carotid artery|internal carotid arterial subdivision http://purl.obolibrary.org/obo/UBERON_0035237 CHEBI:87833 biolink:ChemicalSubstance 2''-O-malonyl-ADP-D-ribose(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87833 chebi_ph7_3 CHEBI:38877 biolink:ChemicalSubstance intravenous anaesthetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_38877 CHEBI:87832 biolink:ChemicalSubstance 2''-O-succinyl-ADP-D-ribose(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87832 chebi_ph7_3 CHEBI:63887 biolink:ChemicalSubstance 1,2-dioleoyl-3-beta-D-galactosylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63887 chebi_ph7_3 CHEBI:87835 biolink:ChemicalSubstance framycetin(6+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87835 chebi_ph7_3 CHEBI:87834 biolink:ChemicalSubstance (S)-4-hydroxy-1-pyrroline-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87834 chebi_ph7_3 CHEBI:87837 biolink:ChemicalSubstance ketocytochalasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87837 chebi_ph7_3 CHEBI:87836 biolink:ChemicalSubstance 2-O-[alpha-D-mannosyl-(1->2)-alpha-D-glucosyl]-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87836 chebi_ph7_3 CHEBI:87839 biolink:ChemicalSubstance cytochalasin Z16 go-plus.json http://purl.obolibrary.org/obo/CHEBI_87839 chebi_ph7_3 CHEBI:87838 biolink:ChemicalSubstance iso-precytochalasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87838 chebi_ph7_3 UBERON:0001884 biolink:AnatomicalEntity phrenic nerve A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. go-plus.json diaphragmatic nerve|phrenic|nervus phrenicus http://purl.obolibrary.org/obo/UBERON_0001884 PR:000001810 biolink:Protein CSF-1/PDGF receptor-type tyrosine-protein kinase A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. go-plus.json http://purl.obolibrary.org/obo/PR_000001810 UBERON:0001886 biolink:AnatomicalEntity choroid plexus A network formed by blood vessels and the tela choroidea which secretes CSF into the ventricular spaces. go-plus.json choroid plexus of cerebral hemisphere|plexus choroideus|plexus choroideus|ventricular choroid plexus|chorioid plexus|CP http://purl.obolibrary.org/obo/UBERON_0001886 PR:000001812 biolink:Protein EGF receptor type tyrosine-protein kinase A protein with core architecture consisting of a signal sequence, a Receptor L domain (Pfam:PF01030), a Furin-like cysteine rich region (Pfam:PF00757), another Receptor L domain, a transmembrane domain, and a Protein tyrosine kinase domain (Pfam:PF07714), that may be followed by up to two YLP motifs (Pfam:PF02757). go-plus.json http://purl.obolibrary.org/obo/PR_000001812 UBERON:0001885 biolink:AnatomicalEntity dentate gyrus of hippocampal formation Part of the hippocampal formation forming a 'V' or 'U' shaped structure with the opening bounded by hippocampal area CA3. It consists of 3 layers from superficial to deep: molecular, granule cell and polymorphic or hilar layer. go-plus.json gyrus dentatus|area dentata|fascia dentata|dentate area (dentate gyrus)|dentate gyrus|hippocampal dentate gyrus|dentate area http://purl.obolibrary.org/obo/UBERON_0001885 PR:000001816 biolink:Protein HGF/MSP receptor type tyrosine-protein kinase A protein with core architecture consisting of a signal sequence, followed by a Sema domain (Pfam:PF01403), three IPT/TIG domains (Pfam:PF01833), a transmembrane region, and a Protein tyrosine kinase domain (Pfam:PF07714). go-plus.json http://purl.obolibrary.org/obo/PR_000001816 UBERON:0001882 biolink:AnatomicalEntity nucleus accumbens A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen. (caudoputamen in rodent) and continuous with these structures. There is no distinct boundary between the nucleus accumbens and the caudate/putamen, but in rodents, it can be identified by its lack of traversing fiber bundles in comparison to the dorsal striatum. Its principle neuron is the medium spiny neuron. Together with the neostriatum (caudate nucleus and putamen), the nucleus accumbens forms the striatum. go-plus.json accumbens nucleus|colliculus of caudate nucleus|nucleus accumbens septi|colliculus nuclei caudati http://purl.obolibrary.org/obo/UBERON_0001882 CHEBI:73201 biolink:ChemicalSubstance 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_73201 CHEBI:38870 biolink:ChemicalSubstance inhalation anaesthetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_38870 CHEBI:73200 biolink:ChemicalSubstance 1-(5-phospho-beta-D-ribosyl)-ATP go-plus.json http://purl.obolibrary.org/obo/CHEBI_73200 CHEBI:73216 biolink:ChemicalSubstance EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73216 CHEBI:73215 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73215 UBERON:0011272 biolink:AnatomicalEntity embryonic skin basal layer go-plus.json basal cell layer of skin|outer epithelium of body http://purl.obolibrary.org/obo/UBERON_0011272 NCBITaxon:131209 biolink:OrganismalEntity Zygnemophyceae go-plus.json Gamophyta|Gamophyceae|Conjugatophyceae|gamophytes|Zygnematophyceae http://purl.obolibrary.org/obo/NCBITaxon_131209 CHEBI:73218 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73218 UBERON:0011270 biolink:AnatomicalEntity dorsal trunk The part of the trunk that is in the dorsum[cjm]. go-plus.json dorsal part of trunk|dorsum of trunk|back of trunk|trunk back http://purl.obolibrary.org/obo/UBERON_0011270 CHEBI:63891 biolink:ChemicalSubstance 3-oxopristanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63891 CHEBI:63894 biolink:ChemicalSubstance pivalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63894 chebi_ph7_3 CHEBI:63893 biolink:ChemicalSubstance 8-hydroxy-alpha-humulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63893 chebi_ph7_3 CHEBI:63892 biolink:ChemicalSubstance zerumbone go-plus.json http://purl.obolibrary.org/obo/CHEBI_63892 chebi_ph7_3 CHEBI:38846 biolink:ChemicalSubstance phenoxyacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38846 chebi_ph7_3 CHEBI:73212 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73212 CHEBI:73229 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73229 CHEBI:24215 biolink:ChemicalSubstance gentiobioside go-plus.json http://purl.obolibrary.org/obo/CHEBI_24215 CHEBI:38853 biolink:ChemicalSubstance decalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38853 chebi_ph7_3 CHEBI:38856 biolink:ChemicalSubstance halophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38856 PR:000001876 biolink:Protein leukemia inhibitory factor receptor A protein that is a translation product of the human LIFR gene or a 1:1 ortholog thereof. go-plus.json CD118|LIF receptor|LIF-R|D-factor/LIF receptor|LIFR http://purl.obolibrary.org/obo/PR_000001876 CHEBI:73223 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73223 CHEBI:73238 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73238 UBERON:0011250 biolink:AnatomicalEntity autopod bone A bone that is part of a autopod region. Note that this incudes the carpal and tarsal bones. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011250 CHEBI:38828 biolink:ChemicalSubstance nonionic surfactant go-plus.json http://purl.obolibrary.org/obo/CHEBI_38828 UBERON:0011249 biolink:AnatomicalEntity appendicular skeletal system Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011249 CHEBI:38825 biolink:ChemicalSubstance tetrafluoromethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38825 chebi_ph7_3 CHEBI:38824 biolink:ChemicalSubstance fluorocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_38824 CHEBI:73234 biolink:ChemicalSubstance 1-hexadecanoyl-2-[(9Z)-octadec-9-enoyl]-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73234 CHEBI:73246 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycerol-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73246 UBERON:0011241 biolink:AnatomicalEntity ethmoid region The most anterior region of the braincase. Provides structural support for peripheral olfactory organ. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011241 CHEBI:38831 biolink:ChemicalSubstance 2-benzofurans go-plus.json http://purl.obolibrary.org/obo/CHEBI_38831 CHEBI:38830 biolink:ChemicalSubstance 1-benzofurans go-plus.json http://purl.obolibrary.org/obo/CHEBI_38830 CHEBI:38836 biolink:ChemicalSubstance 1-benzothiophenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38836 CHEBI:38835 biolink:ChemicalSubstance xanthenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38835 CHEBI:38834 biolink:ChemicalSubstance benzofurochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38834 CHEBI:14885 biolink:ChemicalSubstance prephytoene diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_14885 CHEBI:73241 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73241 PR:000001855 biolink:Protein fractalkine A protein that is a translation product of the human CX3CL1 gene or a 1:1 ortholog thereof. go-plus.json Cx3c|small-inducible cytokine D1|neurotactin|C-X3-C motif chemokine 1|SCYD1|CX3C membrane-anchored chemokine|CX3CL1|NTT|FKN http://purl.obolibrary.org/obo/PR_000001855 CHEBI:73240 biolink:ChemicalSubstance NF-kappaB inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73240 CHEBI:73242 biolink:ChemicalSubstance 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73242 CHEBI:73245 biolink:ChemicalSubstance cucurbitane go-plus.json http://purl.obolibrary.org/obo/CHEBI_73245 chebi_ph7_3 CHEBI:73244 biolink:ChemicalSubstance methyl anthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73244 chebi_ph7_3 GO:0097475 biolink:BiologicalProcess motor neuron migration The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. go-plus.json http://purl.obolibrary.org/obo/GO_0097475 UBERON:0001826 biolink:AnatomicalEntity nasal cavity mucosa The mucous membrane that lines the nasal cavity[MP]. go-plus.json tunica mucosa nasi|mucosa of nose|tunica mucosa nasalis|mucous membrane of nose|nasal mucosa http://purl.obolibrary.org/obo/UBERON_0001826 GO:0097474 biolink:BiologicalProcess retinal cone cell apoptotic process Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina. go-plus.json cone photoreceptor apoptotic process http://purl.obolibrary.org/obo/GO_0097474 GO:0097477 biolink:BiologicalProcess lateral motor column neuron migration The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. go-plus.json http://purl.obolibrary.org/obo/GO_0097477 UBERON:0001828 biolink:AnatomicalEntity gingiva The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth[Glossary of Periodontal Terms 2001]. go-plus.json gum tissue|gum|gums|gingival mucosa http://purl.obolibrary.org/obo/UBERON_0001828 UBERON:0001827 biolink:AnatomicalEntity secretion of lacrimal gland Aqueous substance secreted by the lacrimal gland. go-plus.json tear fluid|tear|lacrimal fluid|lacrimal gland secretion|tears|lacrimal secretion http://purl.obolibrary.org/obo/UBERON_0001827 GO:0097476 biolink:BiologicalProcess spinal cord motor neuron migration The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. go-plus.json http://purl.obolibrary.org/obo/GO_0097476 GO:0097471 biolink:CellularComponent mossy fiber rosette A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes. NIF_Subcellular:nlx_subcell_091021 go-plus.json cerebellar mossy fiber to granule cell synapse http://purl.obolibrary.org/obo/GO_0097471 goslim_synapse UBERON:0001821 biolink:AnatomicalEntity sebaceous gland A holocrine gland that secretes sebum into the hair follicles, or in hairless areas into ducts.[MP]. go-plus.json glandula sebacea|sebaceous follicle|glandula sebaceae http://purl.obolibrary.org/obo/UBERON_0001821 GO:0097470 biolink:CellularComponent ribbon synapse Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm. NIF_Subcellular:sao1884931180 go-plus.json synapsis fasciolaris http://purl.obolibrary.org/obo/GO_0097470 GO:0097473 biolink:BiologicalProcess retinal rod cell apoptotic process Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina. go-plus.json rod photoreceptor apoptotic process http://purl.obolibrary.org/obo/GO_0097473 UBERON:0001824 biolink:AnatomicalEntity mucosa of larynx The mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx. go-plus.json larynx mucous membrane|laryngeal mucosa|organ mucosa of larynx|larynx mucosa|tunica mucosa laryngis|laryngeal mucous membrane|mucosa of organ of larynx|mucous membrane of larynx|larynx mucosa of organ|larynx organ mucosa http://purl.obolibrary.org/obo/UBERON_0001824 GO:0097472 biolink:MolecularActivity cyclin-dependent protein kinase activity Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. go-plus.json http://purl.obolibrary.org/obo/GO_0097472 UBERON:0001823 biolink:AnatomicalEntity nasal cartilage One of the cartilage structures in the nose that provide form and support[WP]. go-plus.json cartilage of nose http://purl.obolibrary.org/obo/UBERON_0001823 UBERON:0001829 biolink:AnatomicalEntity major salivary gland One of the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001829 CHEBI:48299 biolink:ChemicalSubstance butane-1,2,3,4-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48299 chebi_ph7_3 GO:0097479 biolink:BiologicalProcess synaptic vesicle localization Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location. go-plus.json synaptic vesicle localisation|establishment and maintenance of synaptic vesicle position|establishment and maintenance of synaptic vesicle localization http://purl.obolibrary.org/obo/GO_0097479 GO:0097478 biolink:CellularComponent leaflet of membrane bilayer Any of the two layers of lipid molecules that constitute a membrane. go-plus.json membrane leaflet http://purl.obolibrary.org/obo/GO_0097478 UBERON:0001815 biolink:AnatomicalEntity lumbosacral nerve plexus An arrangement of nerve fibers, running from the spine that travels to the pelvic appendage where it innervates skin and muscle. go-plus.json lumbosacral plexus|plexus lumbosacralis|plexus lumbosacralis http://purl.obolibrary.org/obo/UBERON_0001815 GO:0097486 biolink:CellularComponent multivesicular body lumen The volume enclosed by the outermost membrane of a multivesicular body. go-plus.json http://purl.obolibrary.org/obo/GO_0097486 GO:0097485 biolink:BiologicalProcess neuron projection guidance The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json neurite guidance|neuron process guidance|neuronal cell projection guidance|neuron protrusion guidance http://purl.obolibrary.org/obo/GO_0097485 UBERON:0001814 biolink:AnatomicalEntity brachial nerve plexus An arrangement of nerve fibers, running from the spine where it proceeds through the neck then the axilla and into the arm where it innervates skin and muscle. [WP,modified]. go-plus.json plexus brachialis|brachial plexus http://purl.obolibrary.org/obo/UBERON_0001814 UBERON:0001817 biolink:AnatomicalEntity lacrimal gland The lacrimal glands are paired almond-shaped glands, located in or near the orbital region, that secrete the aqueous layer of the tear film.[WP]. go-plus.json tear gland|glandula praeorbitalis|glandula lacrimalis|preorbital gland|lacrimal-preorbital gland http://purl.obolibrary.org/obo/UBERON_0001817 GO:0097488 biolink:CellularComponent multivesicular body, internal vesicle membrane The lipid bilayer surrounding a multivesicular body internal vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097488 UBERON:0001816 biolink:AnatomicalEntity autonomic nerve plexus A nerve plexus that is part of an autonomic nervous system [Automatically generated definition]. go-plus.json plexus visceralis|autonomic plexus|plexus nervosus visceralis|visceral plexus|visceral nerve plexus|plexus autonomicus http://purl.obolibrary.org/obo/UBERON_0001816 GO:0097487 biolink:CellularComponent multivesicular body, internal vesicle A membrane-bounded vesicle wholly contained within a multivesicular body. go-plus.json http://purl.obolibrary.org/obo/GO_0097487 GO:0097482 biolink:CellularComponent muscle cell postsynaptic specialization A postsynaptic specialization that is part of a neuromuscular junction. go-plus.json muscle cell postsynaptic density|muscle fiber postsynaptic density http://purl.obolibrary.org/obo/GO_0097482 GO:0000578 biolink:BiologicalProcess embryonic axis specification The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. go-plus.json embryonic axis determination http://purl.obolibrary.org/obo/GO_0000578 UBERON:0001811 biolink:AnatomicalEntity conjunctiva the mucous membrane that lines the inner surface of the eyelids and the front of the eyeball go-plus.json wall of conjunctival sac|conjunctivas|conjunctivae|tunica conjunctiva http://purl.obolibrary.org/obo/UBERON_0001811 GO:0097481 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097481 UBERON:0001810 biolink:AnatomicalEntity nerve plexus Anatomical junction where subdivisions of two or more neural trees interconnect with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical nerve plexus, brachial nerve plexus, sacral nerve plexus[FMA]. go-plus.json plexus http://purl.obolibrary.org/obo/UBERON_0001810 UBERON:0001813 biolink:AnatomicalEntity spinal nerve plexus an intermingling of fiber fascicles from adjacent spinal nerves to form a network. go-plus.json spinal nerve plexus|plexus of spinal nerves|somatic nerve plexus|plexus nervorum spinalium http://purl.obolibrary.org/obo/UBERON_0001813 GO:0097484 biolink:BiologicalProcess dendrite extension Long distance growth of a single dendrite involved in cellular development. go-plus.json http://purl.obolibrary.org/obo/GO_0097484 GO:0097483 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097483 GO:0097480 biolink:BiologicalProcess establishment of synaptic vesicle localization The directed movement of a synaptic vesicle or vesicles to a specific location. go-plus.json establishment of synaptic vesicle localisation http://purl.obolibrary.org/obo/GO_0097480 CHEBI:143532 biolink:ChemicalSubstance prostaglandin F2alpha-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143532 chebi_ph7_3 UBERON:0001818 biolink:AnatomicalEntity tarsal gland A modified lobulated sebaceous gland at the rim of an eyelid, responsible for the supply of meibum. go-plus.json Meibomian gland|tarsoconjunctival gland|palpebral gland|glandula tarsales|gland of Meibom http://purl.obolibrary.org/obo/UBERON_0001818 CHEBI:48289 biolink:ChemicalSubstance 2-O-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48289 CHEBI:48290 biolink:ChemicalSubstance (R)-2-O-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48290 CHEBI:48291 biolink:ChemicalSubstance (R)-3-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48291 UBERON:0001820 biolink:AnatomicalEntity sweat gland any of the coil glands of the skin that secrete sweat go-plus.json sudoriparous gland|glandula sudorifera|sudoriferous gland http://purl.obolibrary.org/obo/UBERON_0001820 GO:0097489 biolink:CellularComponent multivesicular body, internal vesicle lumen The volume enclosed by the membrane of the multivesicular body internal vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097489 UBERON:0001804 biolink:AnatomicalEntity capsule of lens the elastic, clear, membrane-like structure, that is outer most layer of the lens go-plus.json lens capsule|capsula lentis http://purl.obolibrary.org/obo/UBERON_0001804 GO:0097453 biolink:CellularComponent mesaxon Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide. NIF_Subcellular:sao2127666702 go-plus.json mesaxon of Schwann cell http://purl.obolibrary.org/obo/GO_0097453 UBERON:0001803 biolink:AnatomicalEntity epithelium of lens A layer of epithelial cells that is part of the eye. go-plus.json lens epithelium|lens epithelial tissue|epithelium lentis|epithelial tissue of eye lens|epithelium of eye lens|eye lens epithelium|eye lens epithelial tissue|epithelial tissue of lens http://purl.obolibrary.org/obo/UBERON_0001803 GO:0097452 biolink:CellularComponent GAIT complex A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. go-plus.json IFN-gamma-activated inhibitor of translation complex|gamma interferon-activated inhibitor of translation complex http://purl.obolibrary.org/obo/GO_0097452 CHEBI:48279 biolink:ChemicalSubstance serotonergic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48279 UBERON:0001806 biolink:AnatomicalEntity sympathetic ganglion A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia go-plus.json sympathetic part of autonomic division of nervous system ganglion|ganglion sympathicum|sympathetic nervous system ganglion|ganglion of sympathetic nervous system|ganglion sympatheticum|ganglion of sympathetic part of autonomic division of nervous system http://purl.obolibrary.org/obo/UBERON_0001806 GO:0097455 biolink:CellularComponent spiny bracelet of Nageotte Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin. NIF_Subcellular:sao937871668 go-plus.json http://purl.obolibrary.org/obo/GO_0097455 UBERON:0001805 biolink:AnatomicalEntity autonomic ganglion ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion. go-plus.json ganglion of visceral nervous system|autonomic nervous system ganglion|ganglion of autonomic nervous system|ganglion autonomicum|visceral nervous system ganglion http://purl.obolibrary.org/obo/UBERON_0001805 GO:0097454 biolink:CellularComponent Schwann cell microvillus Small finger-like extension of a Schwann cell that contacts the nodal membrane. NIF_Subcellular:sao1890444066 go-plus.json http://purl.obolibrary.org/obo/GO_0097454 UBERON:0001800 biolink:AnatomicalEntity sensory ganglion The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells. go-plus.json ganglion sensorium http://purl.obolibrary.org/obo/UBERON_0001800 UBERON:0001802 biolink:AnatomicalEntity posterior segment of eyeball any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive) go-plus.json posterior segment of the eye|eye posterior segment|posterior segment eye|posterior eye segment|segmentum posterius bulbi oculi|segmentum posterius (bulbus oculi)|posterior segment of eye http://purl.obolibrary.org/obo/UBERON_0001802 GO:0097451 biolink:CellularComponent glial limiting end-foot Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans. NIF_Subcellular:sao181458425 go-plus.json glial limiting endfoot http://purl.obolibrary.org/obo/GO_0097451 GO:0097450 biolink:CellularComponent astrocyte end-foot Terminal process of astrocyte abutting non-neuronal surfaces in the brain. NIF_Subcellular:sao388182739 go-plus.json astrocyte endfoot http://purl.obolibrary.org/obo/GO_0097450 UBERON:0001801 biolink:AnatomicalEntity anterior segment of eyeball any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) go-plus.json segmentum anterius bulbi oculi|anterior segment of eye|anterior segment eye|anterior eye segment|eye anterior segment|segmentum anterius (bulbus oculi)|anterior segment of the eye http://purl.obolibrary.org/obo/UBERON_0001801 CHEBI:48274 biolink:ChemicalSubstance tryptamine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48274 UBERON:0001808 biolink:AnatomicalEntity parasympathetic ganglion Ganglion containing neurons that receive innervation from parasympathetic neurons in the central nervous system and subserves parasympathetic functions through innervation of smooth muscle, cardiac muscle and glands. go-plus.json ganglion parasympathicum http://purl.obolibrary.org/obo/UBERON_0001808 UBERON:0001807 biolink:AnatomicalEntity paravertebral ganglion Trunk ganglion which is part of a bilaterally paired set of sympathetic ganglia located anterior and lateral to the spinal cord. go-plus.json ganglia of sympathetic trunk|ganglion trunci sympathetici|sympathetic chain ganglia|paravertebral ganglion|paravertebral ganglia|sympathetic chain ganglion|ganglion trunci sympathici|ganglia trunci sympathici|ganglion of sympathetic trunk http://purl.obolibrary.org/obo/UBERON_0001807 CHEBI:48278 biolink:ChemicalSubstance serotonergic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48278 UBERON:0001809 biolink:AnatomicalEntity enteric ganglion . go-plus.json intramural ganglion http://purl.obolibrary.org/obo/UBERON_0001809 CHEBI:143529 biolink:ChemicalSubstance (2E)-decenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_143529 chebi_ph7_3 GO:0097457 biolink:CellularComponent hippocampal mossy fiber Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal. NIF_Subcellular:nlx_subcell_100312 go-plus.json http://purl.obolibrary.org/obo/GO_0097457 GO:0097456 biolink:CellularComponent terminal loop Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath. NIF_Subcellular:sao924713546 go-plus.json terminal loop of Schwann cell http://purl.obolibrary.org/obo/GO_0097456 GO:0097459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097459 GO:0097458 biolink:CellularComponent obsolete neuron part OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0097458 goslim_flybase_ribbon|gocheck_do_not_annotate GO:0097464 biolink:CellularComponent thorny excrescence Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads. NIF_Subcellular:nlx_467 go-plus.json http://purl.obolibrary.org/obo/GO_0097464 GO:0097463 biolink:CellularComponent gemmule Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex. NIF_Subcellular:nlx_subcell_1005003 go-plus.json http://purl.obolibrary.org/obo/GO_0097463 GO:0097466 biolink:BiologicalProcess ubiquitin-dependent glycoprotein ERAD pathway An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component. go-plus.json misfolded or incompletely synthesized glycoprotein catabolic process|glycoprotein ERAD|gpERAD|ER-associated glycoprotein degradation http://purl.obolibrary.org/obo/GO_0097466 GO:0097465 biolink:CellularComponent somatic spine Spine emanating from the cell soma of a neuron. NIF_Subcellular:sao2048514053 go-plus.json http://purl.obolibrary.org/obo/GO_0097465 GO:0097460 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097460 GO:0097462 biolink:CellularComponent Lewy neurite Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease. NIF_Subcellular:sao601362597 go-plus.json http://purl.obolibrary.org/obo/GO_0097462 GO:0097461 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097461 CHEBI:48262 biolink:ChemicalSubstance D-erythrulose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48262 CHEBI:143516 biolink:ChemicalSubstance ultra-long-chain 3-oxoacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143516 chebi_ph7_3 CHEBI:63803 biolink:ChemicalSubstance (E)-2,3-didehydropristanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63803 CHEBI:63801 biolink:ChemicalSubstance N(alpha)-citryl-N(epsilon)-acetyl-N(epsilon)-hydroxylysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63801 GO:0097468 biolink:BiologicalProcess programmed cell death in response to reactive oxygen species Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. go-plus.json reactive oxygen species-mediated programmed cell death|PCD in response to oxidative stress|programmed cell death in response to oxidative stress|PCD in response to reactive oxygen species|reactive oxygen species-mediated PCD http://purl.obolibrary.org/obo/GO_0097468 GO:0097467 biolink:CellularComponent type III terminal bouton Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones. go-plus.json type III terminal button http://purl.obolibrary.org/obo/GO_0097467 GO:0097469 biolink:MolecularActivity obsolete cyclin-dependent protein tyrosine kinase activity OBSOLETE. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit. go-plus.json cyclin-dependent protein tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0097469 UBERON:0001869 biolink:AnatomicalEntity cerebral hemisphere One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA] go-plus.json hemispherium cerebri|hemisphere|medial amygdalar nucleus|cerebrum|nucleus medialis amygdalae|hemispheric regions|nucleus amygdaloideus medialis http://purl.obolibrary.org/obo/UBERON_0001869 CHEBI:24289 biolink:ChemicalSubstance glucosyl-N(6)-isopentenyladenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24289 UBERON:0001866 biolink:AnatomicalEntity sebum Fatty lubricant matter secreted by sebaceous glands, and made of made of triglyceride oils, wax, squalene, and metabolytes of fat-producing cells[BTO,WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001866 UBERON:0001868 biolink:AnatomicalEntity skin of chest A zone of skin that is part of a chest [Automatically generated definition]. go-plus.json chest skin|anterior thoracic region zone of skin|zone of skin of anterior part of thorax|zone of skin of anterior thoracic region|zone of skin of anterior chest|front of thorax zone of skin|chest zone of skin|zone of skin of pectoral part of chest|zone of skin of anterolateral part of thorax|zone of skin of chest|zone of skin of front of thorax|anterolateral part of thorax zone of skin http://purl.obolibrary.org/obo/UBERON_0001868 UBERON:0001867 biolink:AnatomicalEntity cartilage of external ear A cartilage that is part of a external ear [Automatically generated definition]. go-plus.json external ear cartilage http://purl.obolibrary.org/obo/UBERON_0001867 CHEBI:48250 biolink:ChemicalSubstance p-menthane-3,8-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48250 chebi_ph7_3 CHEBI:24282 biolink:ChemicalSubstance glucosyl hydroxycinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24282 CHEBI:24281 biolink:ChemicalSubstance glucosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24281 CHEBI:48251 biolink:ChemicalSubstance 1alpha,3alpha,4beta-p-menthane-3,8-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48251 chebi_ph7_3 CHEBI:24280 biolink:ChemicalSubstance D-glucosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24280 chebi_ph7_3 CHEBI:24287 biolink:ChemicalSubstance glucosylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24287 CHEBI:24286 biolink:ChemicalSubstance glucosylglycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24286 CHEBI:63813 biolink:ChemicalSubstance adenosine 5'-pentaphosphate(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63813 chebi_ph7_3 UBERON:0001873 biolink:AnatomicalEntity caudate nucleus Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species. go-plus.json nucleus caudatus|caudatus|caudatum|Ammon horn fields http://purl.obolibrary.org/obo/UBERON_0001873 UBERON:0001872 biolink:AnatomicalEntity parietal lobe Upper central part of the cerebral hemisphere. (MSH) go-plus.json lobus parietalis|parietal region|regio parietalis http://purl.obolibrary.org/obo/UBERON_0001872 CHEBI:63818 biolink:ChemicalSubstance 1-hexadecyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63818 UBERON:0001875 biolink:AnatomicalEntity globus pallidus Subcortical nucleus, functionally part of the basal ganglia, which consists of two segments the external (or lateral) and internal (or medial) separated by the medial medullary lamina in primates. In rodents, The globus pallidus lateral is separated from the medial segment by the fibers of the internal capsule/cerebral peduncle. go-plus.json paleostriatum|globus pallidus (Burdach)|pallidum|pale body|nucleus pallidus|pallidium http://purl.obolibrary.org/obo/UBERON_0001875 UBERON:0001874 biolink:AnatomicalEntity putamen Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion. go-plus.json nucleus putamen http://purl.obolibrary.org/obo/UBERON_0001874 UBERON:0001871 biolink:AnatomicalEntity temporal lobe Lower lateral part of the cerebral hemisphere. (MSH) go-plus.json temporal cortex|lobus temporalis http://purl.obolibrary.org/obo/UBERON_0001871 UBERON:0001870 biolink:AnatomicalEntity frontal cortex Anterior portion of the neocortex, lying anterior to the central sulcus in humans. It is bounded by the parietal cortex posteriorly and the temporal cortex laterally[NIFSTD,modified]. go-plus.json frontal neocortex|grey matter of frontal lobe|cortex of frontal lobe|gray matter of frontal lobe|frontal lobe cortex http://purl.obolibrary.org/obo/UBERON_0001870 CHEBI:48249 biolink:ChemicalSubstance 1r,3c,4t-p-menthane-3,8-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48249 CHEBI:24298 biolink:ChemicalSubstance glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24298 CHEBI:24297 biolink:ChemicalSubstance glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24297 CHEBI:63821 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63821 CHEBI:63823 biolink:ChemicalSubstance 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63823 chebi_ph7_3 UBERON:0001862 biolink:AnatomicalEntity vestibular labyrinth The part of the membranous labyrinth that includes the utricle and saccule lodged within the vestibule and the semicircular ducts lodged eccentrically in the corresponding canals. go-plus.json labyrinthus vestibularis|vestibular apparatus|vestibular component|inner ear vestibular component http://purl.obolibrary.org/obo/UBERON_0001862 UBERON:0001848 biolink:AnatomicalEntity auricular cartilage cartilage of the pinna and much of the external ear canal. go-plus.json pinna cartilage|cartilage of pinna http://purl.obolibrary.org/obo/UBERON_0001848 GO:0097497 biolink:BiologicalProcess blood vessel endothelial cell delamination The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0097497 CHEBI:24269 biolink:ChemicalSubstance glucosamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24269 GO:0097496 biolink:BiologicalProcess blood vessel lumen ensheathment A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel. go-plus.json http://purl.obolibrary.org/obo/GO_0097496 CHEBI:24268 biolink:ChemicalSubstance glucooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24268 GO:0097499 biolink:BiologicalProcess protein localization to non-motile cilium A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. go-plus.json protein localization to nonmotile primary cilium http://purl.obolibrary.org/obo/GO_0097499 CHEBI:24267 biolink:ChemicalSubstance gluconolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24267 GO:0097498 biolink:BiologicalProcess endothelial tube lumen extension Any endothelial tube morphogenesis process by which the tube is increased in length. go-plus.json http://purl.obolibrary.org/obo/GO_0097498 CHEBI:24266 biolink:ChemicalSubstance gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24266 UBERON:0001849 biolink:AnatomicalEntity membranous labyrinth Organ with organ cavity which consists of the vestibular labyrinth and the cochlear labyrinth. The membranous labyrinth is lodged within the bony labyrinth and has the same general form; it is, however, considerably smaller and is partly separated from the bony walls by a quantity of fluid, the perilymph.[FMA, WP] go-plus.json labyrinthus membranaceus http://purl.obolibrary.org/obo/UBERON_0001849 GO:0000501 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000501 UBERON:0001844 biolink:AnatomicalEntity cochlea the spiral-shaped bony canal in the inner ear containing the hair cells that transduce sound. Its core component is the Organ of Corti, the sensory organ of hearing, which is distributed along the partition separating fluid chambers in the coiled tapered tube of the cochlea. [WP,modified]. go-plus.json cochlear duct|cochlear part of bony labyrinth|cochleae|lagenas|cochlear organ|lagena http://purl.obolibrary.org/obo/UBERON_0001844 GO:0097493 biolink:MolecularActivity structural molecule activity conferring elasticity The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling. go-plus.json http://purl.obolibrary.org/obo/GO_0097493 GO:0000500 biolink:CellularComponent RNA polymerase I upstream activating factor complex A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p. go-plus.json RNA polymerase I upstream activation factor complex|UAF http://purl.obolibrary.org/obo/GO_0000500 UBERON:0001843 biolink:AnatomicalEntity lateral semicircular canal go-plus.json horizontal semicircular canal|lateral semicircular canals|lateral semicircular duct http://purl.obolibrary.org/obo/UBERON_0001843 GO:0097492 biolink:BiologicalProcess sympathetic neuron axon guidance The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json sympathetic neuron axon growth cone guidance|sympathetic neuron axon pathfinding|sympathetic neuron axon chemotaxis http://purl.obolibrary.org/obo/GO_0097492 GO:0097495 biolink:CellularComponent H-NS-Hha complex A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes. go-plus.json http://purl.obolibrary.org/obo/GO_0097495 UBERON:0001846 biolink:AnatomicalEntity internal ear Complex labyrinthine structure that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation. go-plus.json otocyst|labyrinth|auris interna|inner ear http://purl.obolibrary.org/obo/UBERON_0001846 GO:0097494 biolink:BiologicalProcess regulation of vesicle size Any process that modulates the size of a vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0097494 CHEBI:24261 biolink:ChemicalSubstance glucocorticoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24261 GO:0097491 biolink:BiologicalProcess sympathetic neuron projection guidance The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json sympathetic neuron process guidance|sympathetic neurite guidance|sympathetic neuronal cell projection guidance|sympathetic neuron protrusion guidance http://purl.obolibrary.org/obo/GO_0097491 CHEBI:48230 biolink:ChemicalSubstance diphthine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_48230 GO:0097490 biolink:BiologicalProcess sympathetic neuron projection extension Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. go-plus.json sympathetic neuron process extension|sympathetic neuron protrusion extension|sympathetic neurite extension|sympathetic neuronal cell projection extension http://purl.obolibrary.org/obo/GO_0097490 CHEBI:24265 biolink:ChemicalSubstance gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24265 CHEBI:24262 biolink:ChemicalSubstance glucoglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24262 CHEBI:87802 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87802 chebi_ph7_3 CHEBI:63837 biolink:ChemicalSubstance pregn-5-ene-3,20-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_63837 chebi_ph7_3 CHEBI:87804 biolink:ChemicalSubstance 3,3',5-trihydroxybibenzyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_87804 chebi_ph7_3 CHEBI:87803 biolink:ChemicalSubstance 3-(m-hydroxyphenyl)propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87803 chebi_ph7_3 CHEBI:87805 biolink:ChemicalSubstance ethionamide S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87805 chebi_ph7_3 CHEBI:87808 biolink:ChemicalSubstance 2-ethylhexyl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87808 chebi_ph7_3 UBERON:0001851 biolink:AnatomicalEntity cortex Outermost layer of an organ[WP]. go-plus.json cortex of organ|cortex http://purl.obolibrary.org/obo/UBERON_0001851 GO:0000505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000505 GO:0000504 biolink:CellularComponent obsolete proteasome regulatory particle (sensu Bacteria) OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2). go-plus.json 26S proteasome|proteasome regulatory particle (sensu Bacteria) http://purl.obolibrary.org/obo/GO_0000504 GO:0000503 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000503 CHEBI:87809 biolink:ChemicalSubstance 2-ethylhexanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_87809 chebi_ph7_3 GO:0000502 biolink:CellularComponent proteasome complex A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. go-plus.json 26S proteasome|proteasome http://purl.obolibrary.org/obo/GO_0000502 goslim_pir CHEBI:63838 biolink:ChemicalSubstance (24S)-7alpha,24-dihydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_63838 chebi_ph7_3 GO:0000509 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000509 GO:0000508 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000508 GO:0000507 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000507 GO:0000506 biolink:CellularComponent glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast. go-plus.json GPI-GnT complex|GPI-N-acetylglucosaminyltransferase complex|GPI-GlcNAc transferase complex http://purl.obolibrary.org/obo/GO_0000506 UBERON:0001837 biolink:AnatomicalEntity duct of salivary gland The duct of a salivary gland. go-plus.json secretory duct|salivary gland duct|salivary duct http://purl.obolibrary.org/obo/UBERON_0001837 UBERON:0001836 biolink:AnatomicalEntity saliva A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. go-plus.json saliva atomaris|sailva normalis|saliva molecularis|salivary gland secretion http://purl.obolibrary.org/obo/UBERON_0001836 CHEBI:24279 biolink:ChemicalSubstance glucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24279 chebi_ph7_3 UBERON:0001839 biolink:AnatomicalEntity bony labyrinth A system of fluid passages in the inner ear, including both the cochlea, which is part of the auditory system, and the vestibular system, which provides the sense of balance. The bony labyrinth, or osseous labyrinth, is the network of passages with bony walls lined with periosteum. The bony labyrinth is lined with the membranous labyrinth. There is a layer of perilymph between them. The three parts of the bony labyrinth are the vestibule of the ear, the semicircular canals, and the cochlea. The vestibular system is the region of the inner ear where the semicircular canals converge, close to the cochlea (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. Joint and muscle receptors also are important in maintaining balance. The brain receives, interprets, and processes the information from these systems that control our balance. [WP,unvetted]. go-plus.json osseous labyrinth|labyrinthus osseus|osseus labyrinth http://purl.obolibrary.org/obo/UBERON_0001839 CHEBI:24278 biolink:ChemicalSubstance glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_24278 UBERON:0001833 biolink:AnatomicalEntity lip One of the two fleshy folds which surround the opening of the mouth. go-plus.json labia oris|lips http://purl.obolibrary.org/obo/UBERON_0001833 UBERON:0001835 biolink:AnatomicalEntity lower lip Lip that covers the lower portion of the mouth.[TAO]. go-plus.json lower jaw lip|labium inferius oris http://purl.obolibrary.org/obo/UBERON_0001835 UBERON:0001834 biolink:AnatomicalEntity upper lip Lip that covers the upper portion of the mouth.[TAO]. go-plus.json upper jaw lip|labium superius oris http://purl.obolibrary.org/obo/UBERON_0001834 CHEBI:24272 biolink:ChemicalSubstance glucosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24272 CHEBI:24271 biolink:ChemicalSubstance glucosamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24271 CHEBI:24275 biolink:ChemicalSubstance glucosaminylphosphatidylinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24275 CHEBI:24274 biolink:ChemicalSubstance glucosaminylphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24274 CHEBI:24273 biolink:ChemicalSubstance glucosaminylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24273 CHEBI:63844 biolink:ChemicalSubstance 4-carboxyzymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63844 UBERON:0001840 biolink:AnatomicalEntity semicircular canal One of three half-circular, interconnected tubes located inside each ear[WP]. go-plus.json semicircular ducts|ductus semicirculares|scc|canalis semicircularis|semicircular canals http://purl.obolibrary.org/obo/UBERON_0001840 UBERON:0001842 biolink:AnatomicalEntity posterior semicircular canal The posterior semicircular canal is a part of the vestibular system and detects rotations of the head in the sagittal plane. go-plus.json pars superior of labyrinth|posterior semicircular duct|canalis semicircularis posterior|caudal vertical semicircular canal|posterior semicircular canals http://purl.obolibrary.org/obo/UBERON_0001842 UBERON:0001841 biolink:AnatomicalEntity anterior semicircular canal go-plus.json anterior semicircular canals|superior semicircular canal|rostral vertical semicircular canal|anterior semicircular duct|canalis semircularis posterior http://purl.obolibrary.org/obo/UBERON_0001841 GO:0048464 biolink:BiologicalProcess flower calyx development The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048464 PR:000011194 biolink:Protein beta-nerve growth factor A neurotrophin that is a translation product of the human NGF gene or a 1:1 ortholog thereof. go-plus.json beta-NGF|NGFB|NGF http://purl.obolibrary.org/obo/PR_000011194 GO:0048463 biolink:BiologicalProcess carpel structural organization The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure. go-plus.json carpel structural organisation http://purl.obolibrary.org/obo/GO_0048463 GO:0048462 biolink:BiologicalProcess carpel formation The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048462 GO:0048461 biolink:BiologicalProcess flower structural organization The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure. go-plus.json flower structural organisation http://purl.obolibrary.org/obo/GO_0048461 GO:1903629 biolink:BiologicalProcess positive regulation of dUTP diphosphatase activity Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity. go-plus.json up-regulation of dUTP diphosphatase activity|positive regulation of deoxyuridine-triphosphatase activity|positive regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up regulation of deoxyuridine-triphosphatase activity|up-regulation of desoxyuridine 5'-triphosphatase activity|up-regulation of dUTPase activity|upregulation of dUTP pyrophosphatase activity|activation of dUTPase activity|up regulation of dUTP nucleotidohydrolase activity|activation of desoxyuridine 5'-triphosphatase activity|upregulation of dUTP diphosphatase activity|activation of dUTP nucleotidohydrolase activity|positive regulation of dUTP nucleotidohydrolase activity|upregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|upregulation of deoxyuridine-triphosphatase activity|up regulation of dUTP pyrophosphatase activity|up regulation of dUTP diphosphatase activity|positive regulation of dUTPase activity|positive regulation of desoxyuridine 5'-triphosphatase activity|positive regulation of dUTP pyrophosphatase activity|activation of dUTP pyrophosphatase activity|up regulation of desoxyuridine 5'-triphosphatase activity|up regulation of dUTPase activity|activation of dUTP diphosphatase activity|up-regulation of dUTP nucleotidohydrolase activity|up-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up-regulation of deoxyuridine-triphosphatase activity|activation of deoxyuridine-triphosphatase activity|activation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|upregulation of dUTPase activity|upregulation of dUTP nucleotidohydrolase activity|upregulation of desoxyuridine 5'-triphosphatase activity|up-regulation of dUTP pyrophosphatase activity http://purl.obolibrary.org/obo/GO_1903629 GO:0048460 biolink:BiologicalProcess flower formation The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048460 GO:1903628 biolink:BiologicalProcess negative regulation of dUTP diphosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of dUTP diphosphatase activity. go-plus.json down regulation of dUTP nucleotidohydrolase activity|downregulation of dUTP nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of deoxyuridine-triphosphatase activity|down regulation of dUTP pyrophosphatase activity|down regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|down regulation of deoxyuridine-triphosphatase activity|inhibition of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|inhibition of deoxyuridine-triphosphatase activity|down regulation of dUTP diphosphatase activity|negative regulation of dUTP nucleotidohydrolase activity|negative regulation of desoxyuridine 5'-triphosphatase activity|down-regulation of dUTPase activity|down-regulation of desoxyuridine 5'-triphosphatase activity|negative regulation of dUTPase activity|downregulation of dUTP pyrophosphatase activity|down-regulation of dUTP nucleotidohydrolase activity|downregulation of dUTP diphosphatase activity|inhibition of dUTP nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphatase activity|down-regulation of dUTP pyrophosphatase activity|downregulation of dUTPase activity|negative regulation of dUTP pyrophosphatase activity|down-regulation of dUTP diphosphatase activity|down regulation of desoxyuridine 5'-triphosphatase activity|down regulation of dUTPase activity|inhibition of desoxyuridine 5'-triphosphatase activity|inhibition of dUTPase activity|down-regulation of deoxyuridine-triphosphatase activity|negative regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|down-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|negative regulation of deoxyuridine-triphosphatase activity|inhibition of dUTP pyrophosphatase activity|inhibition of dUTP diphosphatase activity http://purl.obolibrary.org/obo/GO_1903628 GO:1903627 biolink:BiologicalProcess regulation of dUTP diphosphatase activity Any process that modulates the frequency, rate or extent of dUTP diphosphatase activity. go-plus.json regulation of dUTP nucleotidohydrolase activity|regulation of deoxyuridine-triphosphatase activity|regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|regulation of dUTP pyrophosphatase activity|regulation of desoxyuridine 5'-triphosphatase activity|regulation of dUTPase activity http://purl.obolibrary.org/obo/GO_1903627 GO:1903626 biolink:BiologicalProcess positive regulation of DNA catabolic process Any process that activates or increases the frequency, rate or extent of DNA catabolic process. go-plus.json up-regulation of DNA breakdown|positive regulation of DNA catabolism|up regulation of DNA catabolism|upregulation of DNA degradation|up-regulation of DNA catabolic process|upregulation of DNA breakdown|upregulation of DNA catabolic process|upregulation of DNA catabolism|up regulation of DNA degradation|activation of DNA degradation|positive regulation of DNA degradation|up regulation of DNA breakdown|activation of DNA breakdown|positive regulation of DNA breakdown|up-regulation of DNA catabolism|activation of DNA catabolism|up regulation of DNA catabolic process|activation of DNA catabolic process|up-regulation of DNA degradation http://purl.obolibrary.org/obo/GO_1903626 GO:1903625 biolink:BiologicalProcess negative regulation of DNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process. go-plus.json inhibition of DNA breakdown|inhibition of DNA catabolic process|downregulation of DNA catabolism|down regulation of DNA degradation|down regulation of DNA catabolism|downregulation of DNA degradation|down regulation of DNA breakdown|inhibition of DNA catabolism|down regulation of DNA catabolic process|downregulation of DNA breakdown|downregulation of DNA catabolic process|negative regulation of DNA degradation|down-regulation of DNA degradation|negative regulation of DNA breakdown|down-regulation of DNA breakdown|inhibition of DNA degradation|down-regulation of DNA catabolic process|down-regulation of DNA catabolism|negative regulation of DNA catabolism http://purl.obolibrary.org/obo/GO_1903625 GO:1903624 biolink:BiologicalProcess regulation of DNA catabolic process Any process that modulates the frequency, rate or extent of DNA catabolic process. go-plus.json regulation of DNA catabolism|regulation of DNA degradation|regulation of DNA breakdown http://purl.obolibrary.org/obo/GO_1903624 GO:1903623 biolink:BiologicalProcess negative regulation of RNA polymerase III activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity. go-plus.json inhibition of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|downregulation of RNA polymerase III activity|down-regulation of RNA polymerase III activity|down regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|inhibition of RNA polymerase III activity|downregulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|negative regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down-regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down regulation of RNA polymerase III activity http://purl.obolibrary.org/obo/GO_1903623 GO:1903622 biolink:BiologicalProcess regulation of RNA polymerase III activity Any process that modulates the frequency, rate or extent of RNA polymerase III activity. go-plus.json regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_1903622 GO:0048469 biolink:BiologicalProcess cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state. go-plus.json functional differentiation http://purl.obolibrary.org/obo/GO_0048469 goslim_pir GO:0048468 biolink:BiologicalProcess cell development The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. go-plus.json terminal differentiation http://purl.obolibrary.org/obo/GO_0048468 goslim_candida GO:1903621 biolink:BiologicalProcess protein localization to photoreceptor connecting cilium A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium. go-plus.json protein localisation to photoreceptor connecting cilium|protein localization in photoreceptor connecting cilium|protein localisation in photoreceptor connecting cilium http://purl.obolibrary.org/obo/GO_1903621 GO:1903620 biolink:BiologicalProcess positive regulation of transdifferentiation Any process that activates or increases the frequency, rate or extent of transdifferentiation. go-plus.json upregulation of transdifferentiation|up-regulation of transdifferentiation|activation of transdifferentiation|up regulation of transdifferentiation http://purl.obolibrary.org/obo/GO_1903620 GO:0048467 biolink:BiologicalProcess gynoecium development The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower. go-plus.json pistil development http://purl.obolibrary.org/obo/GO_0048467 GO:0048466 biolink:BiologicalProcess androecium development The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048466 GO:0048465 biolink:BiologicalProcess corolla development The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048465 GO:0048475 biolink:CellularComponent coated membrane A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0048475 GO:0048474 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048474 GO:0048473 biolink:BiologicalProcess D-methionine transport The directed movement of D-methionine into, out of, within, or between cells. go-plus.json http://purl.obolibrary.org/obo/GO_0048473 GO:0097400 biolink:BiologicalProcess interleukin-17-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-17-mediated signalling pathway|IL-17-mediated signalling pathway|IL-17-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0097400 GO:0048472 biolink:MolecularActivity threonine-phosphate decarboxylase activity Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2). EC:4.1.1.81|KEGG_REACTION:R06530|RHEA:11492|MetaCyc:4.1.1.81-RXN go-plus.json L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]|CobD|L-threonine O-3-phosphate carboxy-lyase activity|L-threonine-O-3-phosphate decarboxylase activity http://purl.obolibrary.org/obo/GO_0048472 GO:0048471 biolink:CellularComponent perinuclear region of cytoplasm Cytoplasm situated near, or occurring around, the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0048471 GO:1903639 biolink:BiologicalProcess regulation of gastrin-induced gastric acid secretion Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_1903639 GO:0048470 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048470 GO:1903638 biolink:BiologicalProcess positive regulation of protein insertion into mitochondrial outer membrane Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane. go-plus.json up regulation of protein transport into mitochondrial outer membrane|positive regulation of protein transport into mitochondrial outer membrane|activation of protein transport into mitochondrial outer membrane|up regulation of mitochondrial outer membrane protein import|upregulation of protein import into mitochondrial outer membrane|activation of mitochondrial outer membrane protein import|positive regulation of mitochondrial outer membrane protein import|up-regulation of protein insertion into mitochondrial outer membrane|positive regulation of protein import into mitochondrial outer membrane|up-regulation of protein import into mitochondrial outer membrane|up-regulation of protein transport into mitochondrial outer membrane|activation of protein import into mitochondrial outer membrane|upregulation of protein insertion into mitochondrial outer membrane|up-regulation of mitochondrial outer membrane protein import|upregulation of protein transport into mitochondrial outer membrane|up regulation of protein import into mitochondrial outer membrane|upregulation of mitochondrial outer membrane protein import|up regulation of protein insertion into mitochondrial outer membrane|activation of protein insertion into mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_1903638 GO:1903637 biolink:BiologicalProcess negative regulation of protein insertion into mitochondrial outer membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane. go-plus.json down-regulation of protein insertion into mitochondrial outer membrane|down regulation of protein import into mitochondrial outer membrane|downregulation of mitochondrial outer membrane protein import|inhibition of protein import into mitochondrial outer membrane|negative regulation of protein import into mitochondrial outer membrane|negative regulation of protein transport into mitochondrial outer membrane|down-regulation of protein transport into mitochondrial outer membrane|inhibition of protein insertion into mitochondrial outer membrane|negative regulation of mitochondrial outer membrane protein import|down-regulation of mitochondrial outer membrane protein import|inhibition of protein transport into mitochondrial outer membrane|inhibition of mitochondrial outer membrane protein import|down regulation of protein insertion into mitochondrial outer membrane|down-regulation of protein import into mitochondrial outer membrane|downregulation of protein insertion into mitochondrial outer membrane|down regulation of protein transport into mitochondrial outer membrane|downregulation of protein import into mitochondrial outer membrane|down regulation of mitochondrial outer membrane protein import|downregulation of protein transport into mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_1903637 GO:1903636 biolink:BiologicalProcess regulation of protein insertion into mitochondrial outer membrane Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane. go-plus.json regulation of mitochondrial outer membrane protein import|regulation of protein import into mitochondrial outer membrane|regulation of protein transport into mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_1903636 GO:1903635 biolink:BiologicalProcess positive regulation of leucine-tRNA ligase activity Any process that activates or increases the frequency, rate or extent of leucine-tRNA ligase activity. go-plus.json up regulation of leucine-tRNA ligase activity|up regulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of leucine translase activity|activation of L-leucine:tRNALeu ligase (AMP-forming)|up-regulation of L-leucine:tRNALeu ligase (AMP-forming)|activation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucine translase activity|upregulation of leucyl-tRNA synthetase activity|upregulation of leucyl-transfer RNA synthetase activity|upregulation of leucine-tRNA synthetase activity|upregulation of leucine-tRNA ligase activity|upregulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of L-leucine:tRNALeu ligase (AMP-forming)|positive regulation of leucyl-transfer ribonucleic acid synthetase activity|upregulation of leucine translase activity|up regulation of L-leucine:tRNALeu ligase (AMP-forming)|up regulation of leucyl-tRNA synthetase activity|up regulation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucyl-transfer RNA synthetase activity|activation of leucyl-tRNA synthetase activity|up-regulation of leucine-tRNA synthetase activity|positive regulation of leucyl-tRNA synthetase activity|activation of leucine-tRNA synthetase activity|activation of leucyl-transfer RNA synthetase activity|positive regulation of leucyl-transfer RNA synthetase activity|up-regulation of leucine-tRNA ligase activity|activation of leucine-tRNA ligase activity|up-regulation of leucyl-transfer ribonucleate synthetase activity|activation of leucyl-transfer ribonucleate synthetase activity|up-regulation of leucine translase activity|activation of leucine translase activity|upregulation of L-leucine:tRNALeu ligase (AMP-forming)|upregulation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucyl-tRNA synthetase activity|positive regulation of leucine-tRNA synthetase activity|up-regulation of leucyl-transfer RNA synthetase activity|up regulation of leucine-tRNA synthetase activity|positive regulation of leucyl-transfer ribonucleate synthetase activity http://purl.obolibrary.org/obo/GO_1903635 GO:1903634 biolink:BiologicalProcess negative regulation of leucine-tRNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity. go-plus.json downregulation of leucine-tRNA synthetase activity|downregulation of leucine-tRNA ligase activity|downregulation of leucyl-transfer ribonucleate synthetase activity|down regulation of leucine-tRNA synthetase activity|downregulation of leucine translase activity|down regulation of leucine-tRNA ligase activity|down regulation of leucyl-transfer ribonucleate synthetase activity|inhibition of leucine-tRNA synthetase activity|down-regulation of L-leucine:tRNALeu ligase (AMP-forming)|negative regulation of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucine-tRNA ligase activity|down regulation of leucyl-tRNA synthetase activity|inhibition of leucyl-transfer ribonucleate synthetase activity|down regulation of leucyl-transfer RNA synthetase activity|negative regulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-transfer ribonucleic acid synthetase activity|down regulation of leucine translase activity|downregulation of leucyl-tRNA synthetase activity|inhibition of leucine translase activity|downregulation of leucyl-transfer RNA synthetase activity|downregulation of L-leucine:tRNALeu ligase (AMP-forming)|downregulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-tRNA synthetase activity|negative regulation of leucyl-tRNA synthetase activity|down regulation of L-leucine:tRNALeu ligase (AMP-forming)|down regulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-transfer RNA synthetase activity|negative regulation of leucyl-transfer RNA synthetase activity|inhibition of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucine-tRNA synthetase activity|negative regulation of leucine-tRNA synthetase activity|down-regulation of leucine-tRNA ligase activity|negative regulation of leucyl-transfer ribonucleate synthetase activity|down-regulation of leucyl-transfer ribonucleate synthetase activity|inhibition of leucyl-tRNA synthetase activity|inhibition of leucyl-transfer RNA synthetase activity|down-regulation of leucine translase activity|negative regulation of leucine translase activity http://purl.obolibrary.org/obo/GO_1903634 GO:1903633 biolink:BiologicalProcess regulation of leucine-tRNA ligase activity Any process that modulates the frequency, rate or extent of leucine-tRNA ligase activity. go-plus.json regulation of leucine-tRNA synthetase activity|regulation of leucyl-transfer ribonucleate synthetase activity|regulation of leucine translase activity|regulation of leucyl-tRNA synthetase activity|regulation of leucyl-transfer RNA synthetase activity|regulation of L-leucine:tRNALeu ligase (AMP-forming)|regulation of leucyl-transfer ribonucleic acid synthetase activity http://purl.obolibrary.org/obo/GO_1903633 GO:1903632 biolink:BiologicalProcess positive regulation of aminoacyl-tRNA ligase activity Any process that activates or increases the frequency, rate or extent of aminoacyl-tRNA ligase activity. go-plus.json upregulation of aminoacyl-tRNA synthetase activity|upregulation of aminoacyl-tRNA ligase activity|positive regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up-regulation of aminoacyl-tRNA synthetase activity|activation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA ligase activity|activation of aminoacyl-tRNA ligase activity|upregulation of aminoacyl-tRNA synthetase auxiliary protein activity|positive regulation of aminoacyl-tRNA synthetase activity|up regulation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up regulation of aminoacyl-tRNA ligase activity|activation of aminoacyl-tRNA synthetase auxiliary protein activity http://purl.obolibrary.org/obo/GO_1903632 GO:0048479 biolink:BiologicalProcess style development The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma. go-plus.json http://purl.obolibrary.org/obo/GO_0048479 GO:1903631 biolink:BiologicalProcess negative regulation of aminoacyl-tRNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of aminoacyl-tRNA ligase activity. go-plus.json inhibition of aminoacyl-tRNA ligase activity|downregulation of aminoacyl-tRNA synthetase auxiliary protein activity|down regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA synthetase activity|negative regulation of aminoacyl-tRNA synthetase activity|down-regulation of aminoacyl-tRNA ligase activity|inhibition of aminoacyl-tRNA synthetase auxiliary protein activity|downregulation of aminoacyl-tRNA synthetase activity|downregulation of aminoacyl-tRNA ligase activity|down regulation of aminoacyl-tRNA synthetase activity|inhibition of aminoacyl-tRNA synthetase activity|down regulation of aminoacyl-tRNA ligase activity|negative regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA synthetase auxiliary protein activity http://purl.obolibrary.org/obo/GO_1903631 GO:0048478 biolink:BiologicalProcess replication fork protection Any process that prevents the collapse of stalled replication forks. go-plus.json replication fork stabilization|replication fork maintenance http://purl.obolibrary.org/obo/GO_0048478 GO:1903630 biolink:BiologicalProcess regulation of aminoacyl-tRNA ligase activity Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity. go-plus.json regulation of aminoacyl-tRNA synthetase auxiliary protein activity|regulation of aminoacyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_1903630 GO:0048477 biolink:BiologicalProcess oogenesis The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. Wikipedia:Oogenesis go-plus.json ovum development http://purl.obolibrary.org/obo/GO_0048477 GO:0048476 biolink:CellularComponent Holliday junction resolvase complex An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated. go-plus.json Mus81-Eme2 complex|resolvasome|Mus81-Eme1 complex|Mus81-Eme1 holliday resolvase complex|Mus81-Eme2 holliday resolvase complex http://purl.obolibrary.org/obo/GO_0048476 goslim_pir GO:0097409 biolink:CellularComponent glial cytoplasmic inclusion Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy. NIF_Subcellular:nlx_subcell_20090703 go-plus.json GCI|Papp-Lantos body http://purl.obolibrary.org/obo/GO_0097409 GO:0097406 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097406 GO:0097405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097405 GO:0097408 biolink:CellularComponent fibrillary inclusion Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra. NIF_Subcellular:sao967812059 go-plus.json http://purl.obolibrary.org/obo/GO_0097408 GO:0097407 biolink:CellularComponent Bunina body Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles. NIF_Subcellular:nlx_subcell_20090101 go-plus.json http://purl.obolibrary.org/obo/GO_0097407 GO:0097402 biolink:BiologicalProcess neuroblast migration The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0097402 GO:0097401 biolink:BiologicalProcess synaptic vesicle lumen acidification The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading. go-plus.json synaptic vesicle lumen pH reduction|synaptic vesicle proton loading http://purl.obolibrary.org/obo/GO_0097401 goslim_synapse GO:0097404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097404 GO:0097403 biolink:BiologicalProcess cellular response to raffinose Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0097403 GO:0048486 biolink:BiologicalProcess parasympathetic nervous system development The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. go-plus.json http://purl.obolibrary.org/obo/GO_0048486 GO:0048485 biolink:BiologicalProcess sympathetic nervous system development The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/GO_0048485 GO:0048484 biolink:BiologicalProcess enteric nervous system development The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. go-plus.json http://purl.obolibrary.org/obo/GO_0048484 GO:0048483 biolink:BiologicalProcess autonomic nervous system development The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. go-plus.json http://purl.obolibrary.org/obo/GO_0048483 GO:0048482 biolink:BiologicalProcess plant ovule morphogenesis The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed. go-plus.json http://purl.obolibrary.org/obo/GO_0048482 GO:0048481 biolink:BiologicalProcess plant ovule development The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed. go-plus.json http://purl.obolibrary.org/obo/GO_0048481 GO:1903649 biolink:BiologicalProcess regulation of cytoplasmic transport Any process that modulates the frequency, rate or extent of cytoplasmic transport. go-plus.json regulation of cytoplasmic streaming http://purl.obolibrary.org/obo/GO_1903649 GO:0048480 biolink:BiologicalProcess stigma development The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky. go-plus.json http://purl.obolibrary.org/obo/GO_0048480 GO:1903648 biolink:BiologicalProcess positive regulation of chlorophyll catabolic process Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process. go-plus.json upregulation of chlorophyll breakdown|positive regulation of chlorophyll catabolism|up regulation of chlorophyll catabolism|upregulation of chlorophyll catabolic process|up regulation of chlorophyll degradation|activation of chlorophyll degradation|positive regulation of chlorophyll degradation|up regulation of chlorophyll breakdown|positive regulation of chlorophyll breakdown|activation of chlorophyll breakdown|upregulation of chlorophyll catabolism|up regulation of chlorophyll catabolic process|activation of chlorophyll catabolic process|up-regulation of chlorophyll degradation|up-regulation of chlorophyll catabolism|up-regulation of chlorophyll breakdown|activation of chlorophyll catabolism|upregulation of chlorophyll degradation|up-regulation of chlorophyll catabolic process http://purl.obolibrary.org/obo/GO_1903648 GO:1903647 biolink:BiologicalProcess negative regulation of chlorophyll catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process. go-plus.json negative regulation of chlorophyll catabolism|down-regulation of chlorophyll catabolism|down regulation of chlorophyll degradation|downregulation of chlorophyll degradation|down regulation of chlorophyll breakdown|downregulation of chlorophyll breakdown|down regulation of chlorophyll catabolic process|downregulation of chlorophyll catabolism|downregulation of chlorophyll catabolic process|down regulation of chlorophyll catabolism|negative regulation of chlorophyll degradation|down-regulation of chlorophyll degradation|inhibition of chlorophyll catabolism|negative regulation of chlorophyll breakdown|down-regulation of chlorophyll breakdown|inhibition of chlorophyll degradation|down-regulation of chlorophyll catabolic process|inhibition of chlorophyll breakdown|inhibition of chlorophyll catabolic process http://purl.obolibrary.org/obo/GO_1903647 GO:1903646 biolink:BiologicalProcess positive regulation of chaperone-mediated protein folding Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding. go-plus.json upregulation of chaperone-mediated protein folding|up-regulation of chaperone-mediated protein folding|activation of chaperone-mediated protein folding|up regulation of chaperone-mediated protein folding http://purl.obolibrary.org/obo/GO_1903646 GO:1903645 biolink:BiologicalProcess negative regulation of chaperone-mediated protein folding Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding. go-plus.json downregulation of chaperone-mediated protein folding|down regulation of chaperone-mediated protein folding|inhibition of chaperone-mediated protein folding|down-regulation of chaperone-mediated protein folding http://purl.obolibrary.org/obo/GO_1903645 GO:1903644 biolink:BiologicalProcess regulation of chaperone-mediated protein folding Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding. go-plus.json http://purl.obolibrary.org/obo/GO_1903644 GO:1903643 biolink:BiologicalProcess positive regulation of recombination hotspot binding Any process that activates or increases the frequency, rate or extent of recombination hotspot binding. go-plus.json up-regulation of recombination hotspot binding|upregulation of DNA binding, recombination hotspot|upregulation of recombination hotspot binding|activation of DNA binding, recombination hotspot|up-regulation of DNA binding, recombination hotspot|up regulation of recombination hotspot binding|activation of recombination hotspot binding|positive regulation of DNA binding, recombination hotspot|up regulation of DNA binding, recombination hotspot http://purl.obolibrary.org/obo/GO_1903643 GO:1903642 biolink:BiologicalProcess regulation of recombination hotspot binding Any process that modulates the frequency, rate or extent of recombination hotspot binding. go-plus.json regulation of DNA binding, recombination hotspot http://purl.obolibrary.org/obo/GO_1903642 GO:0048489 biolink:BiologicalProcess synaptic vesicle transport The directed movement of synaptic vesicles. go-plus.json synaptic vesicle fusion|synaptic vesicle trafficking|synaptic vesicle fission http://purl.obolibrary.org/obo/GO_0048489 goslim_synapse GO:0048488 biolink:BiologicalProcess synaptic vesicle endocytosis A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms. go-plus.json synaptic vesicle retrieval http://purl.obolibrary.org/obo/GO_0048488 goslim_synapse GO:1903641 biolink:BiologicalProcess positive regulation of gastrin-induced gastric acid secretion Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion. go-plus.json up-regulation of gastrin-induced gastric acid secretion|activation of gastrin-induced gastric acid secretion|up regulation of gastrin-induced gastric acid secretion|upregulation of gastrin-induced gastric acid secretion http://purl.obolibrary.org/obo/GO_1903641 GO:0048487 biolink:MolecularActivity beta-tubulin binding Binding to the microtubule constituent protein beta-tubulin. go-plus.json beta tubulin binding http://purl.obolibrary.org/obo/GO_0048487 GO:1903640 biolink:BiologicalProcess negative regulation of gastrin-induced gastric acid secretion Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion. go-plus.json down-regulation of gastrin-induced gastric acid secretion|downregulation of gastrin-induced gastric acid secretion|down regulation of gastrin-induced gastric acid secretion|inhibition of gastrin-induced gastric acid secretion http://purl.obolibrary.org/obo/GO_1903640 GO:1903650 biolink:BiologicalProcess negative regulation of cytoplasmic transport Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport. go-plus.json downregulation of cytoplasmic transport|downregulation of cytoplasmic streaming|down-regulation of cytoplasmic transport|down-regulation of cytoplasmic streaming|negative regulation of cytoplasmic streaming|inhibition of cytoplasmic transport|inhibition of cytoplasmic streaming|down regulation of cytoplasmic transport|down regulation of cytoplasmic streaming http://purl.obolibrary.org/obo/GO_1903650 PR:000011167 biolink:Protein nuclear factor of activated T-cells, cytoplasmic 4 A protein that is a translation product of the human NFATC4 gene or a 1:1 ortholog thereof. go-plus.json NFATC4|NFATc4|NF-ATc4|NF-AT3|T-cell transcription factor NFAT3|NFAT3 http://purl.obolibrary.org/obo/PR_000011167 PR:000011166 biolink:Protein nuclear factor of activated T-cells, cytoplasmic 3 A protein that is a translation product of the human NFATC3 gene or a 1:1 ortholog thereof. go-plus.json NFATc3|NFATC3|NF-ATc3|NFATx|NF-AT4|T-cell transcription factor NFAT4|NFAT4 http://purl.obolibrary.org/obo/PR_000011166 PR:000011164 biolink:Protein nuclear factor of activated T-cells, cytoplasmic 2 A protein that is a translation product of the human NFATC2 gene or a 1:1 ortholog thereof. go-plus.json NFATc2|NFATC2|NF-ATc2|NFAT pre-existing subunit|NF-ATp|T-cell transcription factor NFAT1|NFAT1|NFATP http://purl.obolibrary.org/obo/PR_000011164 CHEBI:143593 biolink:ChemicalSubstance beta-galactosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_143593 chebi_ph7_3 GO:0048497 biolink:BiologicalProcess maintenance of floral organ identity The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0048497 GO:0048496 biolink:BiologicalProcess maintenance of animal organ identity The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0048496 GO:0048495 biolink:MolecularActivity Roundabout binding Binding to Roundabout (ROBO) receptor, a transmembrane receptor. go-plus.json Roundabout receptor binding http://purl.obolibrary.org/obo/GO_0048495 GO:0048494 biolink:CellularComponent chromatophore ribulose bisphosphate carboxylase complex A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. go-plus.json RubisCO complex http://purl.obolibrary.org/obo/GO_0048494 GO:0048493 biolink:CellularComponent plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. go-plus.json ribulose bisphosphate carboxylase complex|plasma membrane ribulose bisphosphate carboxylase complex|RubisCO complex http://purl.obolibrary.org/obo/GO_0048493 GO:0048492 biolink:CellularComponent ribulose bisphosphate carboxylase complex A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. go-plus.json RubisCO complex http://purl.obolibrary.org/obo/GO_0048492 goslim_pir GO:0048491 biolink:BiologicalProcess retrograde synaptic vesicle transport The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body. go-plus.json retrograde axonal transport of synaptic vesicle http://purl.obolibrary.org/obo/GO_0048491 goslim_synapse GO:0048490 biolink:BiologicalProcess anterograde synaptic vesicle transport The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse. go-plus.json anterograde axonal transport of synaptic vesicle http://purl.obolibrary.org/obo/GO_0048490 goslim_synapse GO:1903659 biolink:BiologicalProcess regulation of complement-dependent cytotoxicity Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity. go-plus.json http://purl.obolibrary.org/obo/GO_1903659 GO:1903658 biolink:BiologicalProcess positive regulation of type IV pilus biogenesis Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis. go-plus.json activation of type IV pilus biogenesis|up-regulation of type IV fimbria biogenesis|up regulation of type IV pilus biosynthesis|positive regulation of type IV fimbrial biogenesis|activation of type IV fimbrial biogenesis|activation of type IV fimbria biogenesis|upregulation of type IV fimbrium biogenesis|up-regulation of type 4 pilus biogenesis|positive regulation of TFP biogenesis|up-regulation of type IV fimbriae biogenesis|positive regulation of type IV fimbria assembly|up regulation of TFP biogenesis|up-regulation of type IV fimbrial assembly|up regulation of type IV fimbrium assembly|up regulation of type IV fimbria assembly|activation of type IV fimbrium assembly|upregulation of type IV fimbriae assembly|positive regulation of type IV fimbrium assembly|upregulation of type IV pilus biosynthesis|positive regulation of type IV fimbria biogenesis|up-regulation of type IV fimbrial biogenesis|up regulation of type IV fimbrium biogenesis|up regulation of type IV pilus biogenesis|up regulation of type IV fimbria biogenesis|upregulation of type 4 pilus biogenesis|upregulation of type IV fimbriae biogenesis|positive regulation of type IV fimbrium biogenesis|activation of type IV fimbrium biogenesis|upregulation of type IV fimbrial assembly|upregulation of TFP biogenesis|upregulation of type IV fimbria assembly|up regulation of type IV fimbriae assembly|up-regulation of type IV pilus biosynthesis|up-regulation of type IV fimbrium assembly|positive regulation of type IV fimbriae assembly|activation of type IV fimbriae assembly|activation of type IV pilus biosynthesis|upregulation of type IV fimbrial biogenesis|upregulation of type IV pilus biogenesis|up regulation of type 4 pilus biogenesis|upregulation of type IV fimbria biogenesis|up regulation of type IV fimbriae biogenesis|up regulation of type IV fimbrial assembly|activation of type 4 pilus biogenesis|up-regulation of TFP biogenesis|up-regulation of type IV fimbrium biogenesis|positive regulation of type 4 pilus biogenesis|activation of TFP biogenesis|positive regulation of type IV fimbriae biogenesis|up-regulation of type IV fimbria assembly|activation of type IV fimbriae biogenesis|positive regulation of type IV fimbrial assembly|activation of type IV fimbria assembly|activation of type IV fimbrial assembly|upregulation of type IV fimbrium assembly|positive regulation of type IV pilus biosynthesis|up-regulation of type IV pilus biogenesis|up-regulation of type IV fimbriae assembly|up regulation of type IV fimbrial biogenesis http://purl.obolibrary.org/obo/GO_1903658 GO:1903657 biolink:BiologicalProcess negative regulation of type IV pilus biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis. go-plus.json down-regulation of TFP biogenesis|negative regulation of TFP biogenesis|down-regulation of type IV fimbria assembly|negative regulation of type IV fimbria assembly|downregulation of type IV pilus biosynthesis|downregulation of type IV fimbrium assembly|inhibition of type 4 pilus biogenesis|inhibition of type IV fimbriae biogenesis|negative regulation of type IV fimbrial biogenesis|down regulation of type IV fimbrium biogenesis|down-regulation of type IV fimbrial biogenesis|inhibition of type IV fimbrial assembly|down-regulation of type IV pilus biogenesis|negative regulation of type IV fimbria biogenesis|down-regulation of type IV fimbria biogenesis|down regulation of type IV pilus biosynthesis|inhibition of type IV pilus biosynthesis|downregulation of type IV fimbrium biogenesis|downregulation of TFP biogenesis|downregulation of type IV fimbria assembly|inhibition of type IV fimbrial biogenesis|down regulation of type IV fimbriae assembly|down-regulation of type IV fimbrium assembly|negative regulation of type IV fimbrium assembly|down regulation of TFP biogenesis|down regulation of type IV fimbria assembly|inhibition of TFP biogenesis|inhibition of type IV fimbria assembly|downregulation of type IV pilus biogenesis|downregulation of type IV fimbriae assembly|downregulation of type IV fimbria biogenesis|down regulation of type 4 pilus biogenesis|down regulation of type IV fimbriae biogenesis|inhibition of type IV fimbrium assembly|down-regulation of type IV fimbrium biogenesis|down regulation of type IV fimbrial assembly|negative regulation of type IV fimbrium biogenesis|down regulation of type IV pilus biogenesis|inhibition of type IV pilus biogenesis|downregulation of type 4 pilus biogenesis|down regulation of type IV fimbria biogenesis|downregulation of type IV fimbriae biogenesis|inhibition of type IV fimbria biogenesis|downregulation of type IV fimbrial assembly|negative regulation of type IV fimbriae assembly|inhibition of type IV fimbrium biogenesis|down-regulation of type IV fimbriae assembly|down regulation of type IV fimbrial biogenesis|negative regulation of type IV pilus biosynthesis|down-regulation of type IV pilus biosynthesis|downregulation of type IV fimbrial biogenesis|negative regulation of type 4 pilus biogenesis|down-regulation of type 4 pilus biogenesis|negative regulation of type IV fimbriae biogenesis|down-regulation of type IV fimbriae biogenesis|inhibition of type IV fimbriae assembly|negative regulation of type IV fimbrial assembly|down regulation of type IV fimbrium assembly|down-regulation of type IV fimbrial assembly http://purl.obolibrary.org/obo/GO_1903657 GO:1903656 biolink:BiologicalProcess regulation of type IV pilus biogenesis Any process that modulates the frequency, rate or extent of type IV pilus biogenesis. go-plus.json regulation of type IV fimbrium assembly|regulation of type IV pilus biosynthesis|regulation of type IV fimbrium biogenesis|regulation of TFP biogenesis|regulation of type IV fimbria assembly|regulation of type IV fimbriae assembly|regulation of type IV fimbria biogenesis|regulation of type 4 pilus biogenesis|regulation of type IV fimbriae biogenesis|regulation of type IV fimbrial assembly|regulation of type IV fimbrial biogenesis http://purl.obolibrary.org/obo/GO_1903656 GO:1903655 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1903655 CHEBI:143597 biolink:ChemicalSubstance pentanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_143597 GO:1903654 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1903654 GO:1903653 biolink:BiologicalProcess modulation by symbiont of host cell motility Modulation of host cell motility by a symbiont of that host. go-plus.json modulation by symbiont of host cell movement|regulation by symbiont of host cell motility|modulation by symbiont of host cell locomotion http://purl.obolibrary.org/obo/GO_1903653 GO:0048499 biolink:BiologicalProcess synaptic vesicle membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle. go-plus.json synaptic vesicle membrane organization and biogenesis|SLMV biogenesis|synaptic vesicle membrane organisation http://purl.obolibrary.org/obo/GO_0048499 GO:1903652 biolink:BiologicalProcess modulation by virus of host cytoplasmic transport Modulation by an infecting virus of host cytoplasmic transport. go-plus.json regulation by virus of host cytoplasmic transport|regulation by virus of host cytoplasmic streaming|viral modulation of host cytoplasmic trafficking http://purl.obolibrary.org/obo/GO_1903652 GO:0048498 biolink:BiologicalProcess establishment of petal orientation The process that determines the orientation of petals with reference to the central axis. go-plus.json http://purl.obolibrary.org/obo/GO_0048498 GO:1903651 biolink:BiologicalProcess positive regulation of cytoplasmic transport Any process that activates or increases the frequency, rate or extent of cytoplasmic transport. go-plus.json up regulation of cytoplasmic transport|up regulation of cytoplasmic streaming|activation of cytoplasmic transport|positive regulation of cytoplasmic streaming|activation of cytoplasmic streaming|up-regulation of cytoplasmic transport|up-regulation of cytoplasmic streaming|upregulation of cytoplasmic transport|upregulation of cytoplasmic streaming http://purl.obolibrary.org/obo/GO_1903651 GO:1903661 biolink:BiologicalProcess positive regulation of complement-dependent cytotoxicity Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity. go-plus.json up-regulation of complement-dependent cytotoxicity|upregulation of complement-dependent cytotoxicity|up regulation of complement-dependent cytotoxicity|activation of complement-dependent cytotoxicity http://purl.obolibrary.org/obo/GO_1903661 GO:1903660 biolink:BiologicalProcess negative regulation of complement-dependent cytotoxicity Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity. go-plus.json down regulation of complement-dependent cytotoxicity|downregulation of complement-dependent cytotoxicity|down-regulation of complement-dependent cytotoxicity|inhibition of complement-dependent cytotoxicity http://purl.obolibrary.org/obo/GO_1903660 NCBITaxon:238069 biolink:OrganismalEntity Saliceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_238069 GO:0097431 biolink:CellularComponent mitotic spindle pole Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0097431 GO:0000486 biolink:BiologicalProcess cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000486 UBERON:0001902 biolink:AnatomicalEntity epithelium of small intestine An epithelium that is part of a small intestine [Automatically generated definition]. go-plus.json epithelial tissue of small intestine|small intestine epithelial tissue|small intestine epithelium|mid intestine epithelium|small bowel epithelium|small intestinal epithelium|epithelium of small bowel|epithelial tissue of small bowel|small bowel epithelial tissue http://purl.obolibrary.org/obo/UBERON_0001902 GO:0000485 biolink:BiologicalProcess cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000485 GO:0097430 biolink:BiologicalProcess copper ion import across prospore membrane The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol. go-plus.json copper ion import across prospore membrane|copper ion import into ascospore-type prospore|copper ion transport into forespores http://purl.obolibrary.org/obo/GO_0097430 UBERON:0001905 biolink:AnatomicalEntity pineal body A midline, cone like structure located in the dorso-caudal roof of the 3rd ventricle, attached by peduncles to the habenular and posterior commissures. The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399). go-plus.json frontal organ|pineal gland (Galen)|epiphysis cerebri|pineal|epiphysis|corpus pineale|Pi|glandula pinealis|pineal gland|pineal organ|conarium|stirnorgan http://purl.obolibrary.org/obo/UBERON_0001905 GO:0000484 biolink:BiologicalProcess cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000484 GO:0097433 biolink:CellularComponent dense body An electron dense body which may contain granules. NIF_Subcellular:sao730872736 go-plus.json http://purl.obolibrary.org/obo/GO_0097433 UBERON:0001904 biolink:AnatomicalEntity habenula A segment of the epithalamus that has as its parts the habenular nuclei and the habenular commissure[FMA,modified]. go-plus.json ganglion intercrurale|nuclei habenulares|habenular nuclei|pineal peduncle|nucleus habenularis|ganglion interpedunculare|Hb|habenulae|habenula complex|habenular complex http://purl.obolibrary.org/obo/UBERON_0001904 GO:0097432 biolink:BiologicalProcess hippocampal pyramidal neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus. go-plus.json http://purl.obolibrary.org/obo/GO_0097432 GO:0000483 biolink:BiologicalProcess endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species. go-plus.json http://purl.obolibrary.org/obo/GO_0000483 GO:0000489 biolink:BiologicalProcess maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000489 UBERON:0001901 biolink:AnatomicalEntity epithelium of trachea the epithelial lining of the trachea which contains numerous ciliated cells go-plus.json windpipe epithelium|epithelial tissue of trachea|trachea epithelial tissue|epithelial tissue of windpipe|epithelium of windpipe|trachea epithelium|tracheal epithelium|windpipe epithelial tissue http://purl.obolibrary.org/obo/UBERON_0001901 GO:0000488 biolink:BiologicalProcess maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000488 UBERON:0001900 biolink:AnatomicalEntity ventral thalamus Anterior part of the diencephalon that lies between the dorsal thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis[GO, modified]. go-plus.json thalamus ventralis|SbTh|perithalamus|subthalamic region|subthalamus|prethalamus|ventral thalamus http://purl.obolibrary.org/obo/UBERON_0001900 GO:0000487 biolink:BiologicalProcess maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000487 GO:1903669 biolink:BiologicalProcess positive regulation of chemorepellent activity Any process that activates or increases the frequency, rate or extent of chemorepellent activity. go-plus.json up-regulation of chemorepellant activity|up-regulation of chemorepellent activity|upregulation of chemorepellant activity|upregulation of chemorepellent activity|up regulation of chemorepellant activity|activation of chemorepellant activity|positive regulation of chemorepellant activity|up regulation of chemorepellent activity|activation of chemorepellent activity http://purl.obolibrary.org/obo/GO_1903669 GO:1903668 biolink:BiologicalProcess negative regulation of chemorepellent activity Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity. go-plus.json inhibition of chemorepellant activity|inhibition of chemorepellent activity|down regulation of chemorepellant activity|downregulation of chemorepellant activity|down regulation of chemorepellent activity|downregulation of chemorepellent activity|down-regulation of chemorepellant activity|negative regulation of chemorepellant activity|down-regulation of chemorepellent activity http://purl.obolibrary.org/obo/GO_1903668 GO:1903667 biolink:BiologicalProcess regulation of chemorepellent activity Any process that modulates the frequency, rate or extent of chemorepellent activity. go-plus.json regulation of chemorepellant activity http://purl.obolibrary.org/obo/GO_1903667 GO:1903666 biolink:BiologicalProcess positive regulation of asexual reproduction Any process that activates or increases the frequency, rate or extent of asexual reproduction. go-plus.json up regulation of asexual reproduction|upregulation of asexual reproduction|up-regulation of asexual reproduction|activation of asexual reproduction http://purl.obolibrary.org/obo/GO_1903666 GO:0000482 biolink:BiologicalProcess maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000482 GO:1903665 biolink:BiologicalProcess negative regulation of asexual reproduction Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction. go-plus.json downregulation of asexual reproduction|down regulation of asexual reproduction|inhibition of asexual reproduction|down-regulation of asexual reproduction http://purl.obolibrary.org/obo/GO_1903665 UBERON:0001906 biolink:AnatomicalEntity subthalamic nucleus The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function[GO]. go-plus.json Luy's body|corpus subthalamicum|nucleus of corpus luysii|subthalamic nucleus of Luys|nucleus of Luys|subthalamic nucleus (of Luys)|Luys' body|Luys' nucleus|nucleus subthalamicus|body of Luys|corpus Luysi|body of Forel http://purl.obolibrary.org/obo/UBERON_0001906 GO:1903664 biolink:BiologicalProcess regulation of asexual reproduction Any process that modulates the frequency, rate or extent of asexual reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_1903664 GO:0000481 biolink:BiologicalProcess maturation of 5S rRNA Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0000481 UBERON:0001909 biolink:AnatomicalEntity habenular commissure A brain commissure that is situated in front of the pineal gland and connects the habenular nucleus on one side of the diencephalon with that on the other side. go-plus.json HBC|commissure habenularum|commissura habenularum|habenular commisure|commissura habenularis|habenular commissure (Haller) http://purl.obolibrary.org/obo/UBERON_0001909 GO:1903663 biolink:BiologicalProcess L-altrarate catabolic process The chemical reactions and pathways resulting in the breakdown of L-altrarate. go-plus.json L-altrarate(1-) degradation|L-altrarate(1-) breakdown|L-altrarate(1-) catabolism http://purl.obolibrary.org/obo/GO_1903663 GO:0000480 biolink:BiologicalProcess endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable. go-plus.json endonucleolytic cleavage at A0|endonucleolytic cleavage at A-prime http://purl.obolibrary.org/obo/GO_0000480 UBERON:0001908 biolink:AnatomicalEntity optic tract Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm[ZFA]. Predominantly white matter structure found in diencephalon consisting of fibers originating in the retina. The optic tract is considered to extend from the point of the optic chiasm and terminates largely, although not exclusively, in the lateral geniculate complex. Other fibers end in the superior colliculus and other structures in the diencephalon, midbrain and brainstem (MM)[NIF]. go-plus.json tractus opticus|optic tracts|optic lemniscus|visual pathway|tractus optici http://purl.obolibrary.org/obo/UBERON_0001908 GO:1903662 biolink:BiologicalProcess L-altrarate metabolic process The chemical reactions and pathways involving L-altrarate. go-plus.json L-altrarate(1-) metabolism http://purl.obolibrary.org/obo/GO_1903662 GO:1903672 biolink:BiologicalProcess positive regulation of sprouting angiogenesis Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis. go-plus.json up regulation of sprouting angiogenesis|upregulation of sprouting angiogenesis|up-regulation of sprouting angiogenesis|activation of sprouting angiogenesis http://purl.obolibrary.org/obo/GO_1903672 GO:1903671 biolink:BiologicalProcess negative regulation of sprouting angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis. go-plus.json downregulation of sprouting angiogenesis|down regulation of sprouting angiogenesis|inhibition of sprouting angiogenesis|down-regulation of sprouting angiogenesis http://purl.obolibrary.org/obo/GO_1903671 GO:1903670 biolink:BiologicalProcess regulation of sprouting angiogenesis Any process that modulates the frequency, rate or extent of sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1903670 GO:0097439 biolink:BiologicalProcess acquisition of desiccation tolerance The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state. go-plus.json http://purl.obolibrary.org/obo/GO_0097439 GO:0097438 biolink:BiologicalProcess exit from dormancy The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated. go-plus.json release from dormancy http://purl.obolibrary.org/obo/GO_0097438 GO:0097435 biolink:BiologicalProcess supramolecular fiber organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. go-plus.json fibril organization|extracellular fibril organization and biogenesis|extracellular fibril organisation|fibril organisation|extracellular fibril organization http://purl.obolibrary.org/obo/GO_0097435 GO:0097434 biolink:MolecularActivity succinate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in). go-plus.json succinate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0097434 GO:0097437 biolink:BiologicalProcess maintenance of dormancy The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated. go-plus.json http://purl.obolibrary.org/obo/GO_0097437 GO:0097436 biolink:BiologicalProcess entry into dormancy The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated. go-plus.json induction of dormancy http://purl.obolibrary.org/obo/GO_0097436 GO:0097442 biolink:CellularComponent CA3 pyramidal cell dendrite A dendrite of a hippocampal CA3 pyramidal cell. NIF_Subcellular:nlx_subcell_1005001 go-plus.json http://purl.obolibrary.org/obo/GO_0097442 GO:0000497 biolink:MolecularActivity DNA template activity Binding to nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule. go-plus.json base pairing with DNA http://purl.obolibrary.org/obo/GO_0000497 GO:0097441 biolink:CellularComponent basal dendrite A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon. NIF_Subcellular:sao1079900774 go-plus.json basilar dendrite http://purl.obolibrary.org/obo/GO_0097441 GO:0000496 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000496 GO:0097444 biolink:CellularComponent spine apparatus A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material. The endomembrane component is continuous with the smooth endoplasmic reticulum. NIF_Subcellular:sao725931194 go-plus.json dense material http://purl.obolibrary.org/obo/GO_0097444 goslim_synapse GO:0000495 biolink:BiologicalProcess box H/ACA RNA 3'-end processing Any process involved in forming the mature 3' end of a box H/ACA RNA molecule. go-plus.json box H/ACA RNA 3' end processing|box H/ACA sRNA 3'-end processing|box H/ACA snoRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0000495 GO:0097443 biolink:CellularComponent sorting endosome A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles. NIF_Subcellular:sao1028571114 go-plus.json MVB-tubule complex http://purl.obolibrary.org/obo/GO_0097443 GO:0000494 biolink:BiologicalProcess box C/D RNA 3'-end processing Any process involved in forming the mature 3' end of a box C/D RNA molecule. go-plus.json box C/D RNA 3' end processing|box C/D sRNA 3'-end processing|box C/D snoRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0000494 GO:0097440 biolink:CellularComponent apical dendrite A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon. NIF_Subcellular:sao273773228 go-plus.json http://purl.obolibrary.org/obo/GO_0097440 GO:0000499 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000499 GO:0000498 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000498 GO:1903679 biolink:BiologicalProcess positive regulation of cap-independent translational initiation Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation. go-plus.json up regulation of cap-independent translational initiation|upregulation of cap-independent translational initiation|activation of cap-independent translational initiation|up-regulation of cap-independent translational initiation http://purl.obolibrary.org/obo/GO_1903679 GO:1903678 biolink:BiologicalProcess negative regulation of cap-independent translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation. go-plus.json downregulation of cap-independent translational initiation|down regulation of cap-independent translational initiation|inhibition of cap-independent translational initiation|down-regulation of cap-independent translational initiation http://purl.obolibrary.org/obo/GO_1903678 GO:1903677 biolink:BiologicalProcess regulation of cap-independent translational initiation Any process that modulates the frequency, rate or extent of cap-independent translational initiation. go-plus.json http://purl.obolibrary.org/obo/GO_1903677 GO:1903676 biolink:BiologicalProcess positive regulation of cap-dependent translational initiation Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation. go-plus.json up regulation of cap-dependent translational initiation|upregulation of cap-dependent translational initiation|up-regulation of cap-dependent translational initiation|activation of cap-dependent translational initiation http://purl.obolibrary.org/obo/GO_1903676 GO:0000493 biolink:BiologicalProcess box H/ACA snoRNP assembly The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex. go-plus.json box H/ACA small nucleolar ribonucleoprotein complex assembly http://purl.obolibrary.org/obo/GO_0000493 GO:1903675 biolink:BiologicalProcess negative regulation of cap-dependent translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation. go-plus.json down-regulation of cap-dependent translational initiation|downregulation of cap-dependent translational initiation|down regulation of cap-dependent translational initiation|inhibition of cap-dependent translational initiation http://purl.obolibrary.org/obo/GO_1903675 GO:0000492 biolink:BiologicalProcess box C/D snoRNP assembly The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex. go-plus.json box C/D small nucleolar ribonucleoprotein complex assembly http://purl.obolibrary.org/obo/GO_0000492 GO:1903674 biolink:BiologicalProcess regulation of cap-dependent translational initiation Any process that modulates the frequency, rate or extent of cap-dependent translational initiation. go-plus.json http://purl.obolibrary.org/obo/GO_1903674 GO:0000491 biolink:BiologicalProcess small nucleolar ribonucleoprotein complex assembly The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex. go-plus.json snoRNP assembly http://purl.obolibrary.org/obo/GO_0000491 GO:1903673 biolink:BiologicalProcess mitotic cleavage furrow formation Any cleavage furrow formation that is involved in mitotic cell cycle. go-plus.json cleavage furrow positioning involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903673 GO:0000490 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000490 GO:1903683 biolink:BiologicalProcess positive regulation of epithelial cell-cell adhesion involved in epithelium migration Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration. go-plus.json up regulation of epithelial cell-cell adhesion involved in epithelium migration|upregulation of epithelial cell-cell adhesion involved in epithelium migration|up-regulation of epithelial cell-cell adhesion involved in epithelium migration|activation of epithelial cell-cell adhesion involved in epithelium migration http://purl.obolibrary.org/obo/GO_1903683 GO:1903682 biolink:BiologicalProcess negative regulation of epithelial cell-cell adhesion involved in epithelium migration Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration. go-plus.json downregulation of epithelial cell-cell adhesion involved in epithelium migration|down regulation of epithelial cell-cell adhesion involved in epithelium migration|inhibition of epithelial cell-cell adhesion involved in epithelium migration|down-regulation of epithelial cell-cell adhesion involved in epithelium migration http://purl.obolibrary.org/obo/GO_1903682 GO:1903681 biolink:BiologicalProcess regulation of epithelial cell-cell adhesion involved in epithelium migration Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration. go-plus.json http://purl.obolibrary.org/obo/GO_1903681 GO:1903680 biolink:BiologicalProcess acinar cell of sebaceous gland differentiation The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland. go-plus.json sebocyte differentiation http://purl.obolibrary.org/obo/GO_1903680 GO:0097449 biolink:CellularComponent astrocyte projection A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. NIF_Subcellular:sao1630537580 go-plus.json peripheral astrocyte process|astrocyte process|vellous process http://purl.obolibrary.org/obo/GO_0097449 GO:0097446 biolink:BiologicalProcess protein localization to eisosome filament A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1. go-plus.json protein localization to linear eisosome http://purl.obolibrary.org/obo/GO_0097446 GO:0097445 biolink:CellularComponent presynaptic active zone dense projection Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered. NIF_Subcellular:sao494258938 go-plus.json active zone dense projection|pre-synaptic active zone dense projection http://purl.obolibrary.org/obo/GO_0097445 GO:0097448 biolink:CellularComponent spine mat A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma. NIF_Subcellular:sao2128156969 go-plus.json http://purl.obolibrary.org/obo/GO_0097448 GO:0097447 biolink:CellularComponent dendritic tree The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. NIF_Subcellular:sao172297168 go-plus.json http://purl.obolibrary.org/obo/GO_0097447 GO:0000464 biolink:BiologicalProcess endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs. go-plus.json endonucleolytic cleavage at A3 http://purl.obolibrary.org/obo/GO_0000464 GO:0000463 biolink:BiologicalProcess maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000463 GO:0000462 biolink:BiologicalProcess maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. go-plus.json maturation of 18S rRNA http://purl.obolibrary.org/obo/GO_0000462 GO:0097411 biolink:BiologicalProcess hypoxia-inducible factor-1alpha signaling pathway A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. go-plus.json HIF1alpha pathway|hypoxia-inducible factor-1alpha signalling pathway|hypoxia-inducible factor signaling http://purl.obolibrary.org/obo/GO_0097411 GO:0097410 biolink:BiologicalProcess hippocampal interneuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron. go-plus.json http://purl.obolibrary.org/obo/GO_0097410 GO:0000461 biolink:BiologicalProcess endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA. go-plus.json endonucleolytic cleavage at site D http://purl.obolibrary.org/obo/GO_0000461 GO:0000468 biolink:BiologicalProcess generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json processing at B2 http://purl.obolibrary.org/obo/GO_0000468 GO:0000467 biolink:BiologicalProcess exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000467 GO:0000466 biolink:BiologicalProcess maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000466 GO:0000465 biolink:BiologicalProcess exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000465 CHEBI:143566 biolink:ChemicalSubstance 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_143566 chebi_ph7_3 GO:1903689 biolink:BiologicalProcess regulation of wound healing, spreading of epidermal cells Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_1903689 GO:1903688 biolink:BiologicalProcess positive regulation of border follicle cell migration Any process that activates or increases the frequency, rate or extent of border follicle cell migration. go-plus.json activation of border follicle cell migration http://purl.obolibrary.org/obo/GO_1903688 GO:1903687 biolink:BiologicalProcess negative regulation of border follicle cell migration Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration. go-plus.json inhibition of border follicle cell migration http://purl.obolibrary.org/obo/GO_1903687 GO:0000460 biolink:BiologicalProcess maturation of 5.8S rRNA Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0000460 CHEBI:143563 biolink:ChemicalSubstance 3beta-hydroxy-4,4-dimethylsteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_143563 chebi_ph7_3 GO:1903684 biolink:BiologicalProcess regulation of border follicle cell migration Any process that modulates the frequency, rate or extent of border follicle cell migration. go-plus.json regulation of border cell migration http://purl.obolibrary.org/obo/GO_1903684 GO:1903694 biolink:BiologicalProcess obsolete positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation. go-plus.json up-regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|activation of mitotic G1 cell cycle arrest in response to nitrogen starvation|upregulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up-regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|up regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|activation of G1 mitotic cell cycle arrest in response to nitrogen starvation|positive regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|upregulation of mitotic G1 cell cycle arrest in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_1903694 GO:1903693 biolink:BiologicalProcess obsolete regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation. go-plus.json regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_1903693 GO:1903692 biolink:BiologicalProcess methionine import across plasma membrane The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json methionine import into cell|methionine import http://purl.obolibrary.org/obo/GO_1903692 GO:1903691 biolink:BiologicalProcess positive regulation of wound healing, spreading of epidermal cells Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells. go-plus.json upregulation of wound healing, spreading of epidermal cells|up regulation of wound healing, spreading of epidermal cells|activation of wound healing, spreading of epidermal cells|up-regulation of wound healing, spreading of epidermal cells http://purl.obolibrary.org/obo/GO_1903691 GO:1903690 biolink:BiologicalProcess negative regulation of wound healing, spreading of epidermal cells Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells. go-plus.json down regulation of wound healing, spreading of epidermal cells|downregulation of wound healing, spreading of epidermal cells|down-regulation of wound healing, spreading of epidermal cells|inhibition of wound healing, spreading of epidermal cells http://purl.obolibrary.org/obo/GO_1903690 GO:0097417 biolink:CellularComponent nematosome Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles. NIF_Subcellular:sao138430598 go-plus.json http://purl.obolibrary.org/obo/GO_0097417 GO:0097416 biolink:CellularComponent Lewy body-like hyaline inclusion Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments. NIF_Subcellular:nlx_subcell_20090105 go-plus.json LBHI http://purl.obolibrary.org/obo/GO_0097416 GO:0097419 biolink:CellularComponent Pick body Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E. NIF_Subcellular:nlx_subcell_20090102 go-plus.json http://purl.obolibrary.org/obo/GO_0097419 GO:0000469 biolink:BiologicalProcess cleavage involved in rRNA processing Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. go-plus.json cleavage during rRNA processing http://purl.obolibrary.org/obo/GO_0000469 GO:0097418 biolink:CellularComponent neurofibrillary tangle Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star. NIF_Subcellular:nlx_subcell_20090202|NIF_Subcellular:nlx_subcell_20090201|NIF_Subcellular:sao2409833926 go-plus.json flame-shaped neurofibrillary tangle|star-shaped neurofibrillary tangle http://purl.obolibrary.org/obo/GO_0097418 GO:0097413 biolink:CellularComponent Lewy body Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein. NIF_Subcellular:sao4933778419 go-plus.json cytoplasmic inclusion http://purl.obolibrary.org/obo/GO_0097413 GO:0097412 biolink:CellularComponent hyaline inclusion A glass-like, pale intracellular inclusion. NIF_Subcellular:nlx_subcell_20090104 go-plus.json pale body http://purl.obolibrary.org/obo/GO_0097412 SO:0000410 biolink:SequenceFeature protein_binding_site A binding site that, in the molecule, interacts selectively and non-covalently with polypeptide molecules. go-plus.json protein binding site|INSDC_feature:protein_bind http://purl.obolibrary.org/obo/SO_0000410 SOFA GO:0097415 biolink:CellularComponent cortical Lewy body Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils. NIF_Subcellular:sao4040591221 go-plus.json http://purl.obolibrary.org/obo/GO_0097415 GO:0097414 biolink:CellularComponent classical Lewy body Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils. NIF_Subcellular:sao4749542545 go-plus.json brainstem Lewy body http://purl.obolibrary.org/obo/GO_0097414 GO:0097420 biolink:CellularComponent skein-like inclusion Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin. NIF_Subcellular:nlx_subcell_20090103 go-plus.json http://purl.obolibrary.org/obo/GO_0097420 GO:0000475 biolink:BiologicalProcess maturation of 2S rRNA Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0000475 GO:0000474 biolink:BiologicalProcess maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000474 GO:0000473 biolink:BiologicalProcess maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0000473 GO:0097422 biolink:CellularComponent tubular endosome A network of fine tubules in the vicinity of the Golgi complex and around the centriole. NIF_Subcellular:sao1570660411|NIF_Subcellular:sao694815499 go-plus.json coated tip http://purl.obolibrary.org/obo/GO_0097422 GO:0097421 biolink:BiologicalProcess liver regeneration The regrowth of lost or destroyed liver. go-plus.json http://purl.obolibrary.org/obo/GO_0097421 GO:0000472 biolink:BiologicalProcess endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA. go-plus.json endonucleolytic cleavage at A1 http://purl.obolibrary.org/obo/GO_0000472 GO:0000479 biolink:BiologicalProcess endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0000479 GO:0000478 biolink:BiologicalProcess endonucleolytic cleavage involved in rRNA processing Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA. go-plus.json endonucleolytic cleavage during rRNA processing http://purl.obolibrary.org/obo/GO_0000478 GO:0000477 biolink:BiologicalProcess generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. go-plus.json processing at C1 http://purl.obolibrary.org/obo/GO_0000477 GO:0000476 biolink:BiologicalProcess maturation of 4.5S rRNA Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0000476 GO:1903699 biolink:BiologicalProcess tarsal gland development The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure. go-plus.json Meibomian gland development|tarsoconjunctival gland development|glandula tarsales development|gland of Meibom development http://purl.obolibrary.org/obo/GO_1903699 GO:1903698 biolink:BiologicalProcess positive regulation of microvillus assembly Any process that activates or increases the frequency, rate or extent of microvillus assembly. go-plus.json up-regulation of microvillus assembly|activation of microvillus assembly|upregulation of microvillus biogenesis|up-regulation of microvillus biogenesis|up regulation of microvillus assembly|activation of microvillus biogenesis|positive regulation of microvillus biogenesis|upregulation of microvillus assembly|up regulation of microvillus biogenesis http://purl.obolibrary.org/obo/GO_1903698 GO:0000471 biolink:BiologicalProcess endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events. go-plus.json http://purl.obolibrary.org/obo/GO_0000471 GO:1903697 biolink:BiologicalProcess negative regulation of microvillus assembly Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. go-plus.json down regulation of microvillus biogenesis|inhibition of microvillus biogenesis|down-regulation of microvillus assembly|downregulation of microvillus assembly|down-regulation of microvillus biogenesis|negative regulation of microvillus biogenesis|down regulation of microvillus assembly|inhibition of microvillus assembly|downregulation of microvillus biogenesis http://purl.obolibrary.org/obo/GO_1903697 GO:0000470 biolink:BiologicalProcess maturation of LSU-rRNA Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0000470 GO:1903696 biolink:BiologicalProcess protein localization to horsetail-astral microtubule array A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array. go-plus.json protein localization in horsetail-astral microtubule array|protein localisation to horsetail-astral microtubule array|protein localisation in horsetail-astral microtubule array http://purl.obolibrary.org/obo/GO_1903696 GO:1903695 biolink:BiologicalProcess obsolete MAPK cascade involved in ascospore formation OBSOLETE. Any MAPK cascade that is involved in ascospore formation. go-plus.json MAPKKK cascade during sporulation involved in ascospore formation|MAPK signalling involved in ascospore biosynthesis|MAP kinase kinase kinase cascade involved in ascospore formation|MAP kinase cascade involved in ascospore formation|MAPKKK cascade during sporulation involved in ascospore biosynthesis|mitogen-activated protein kinase cascade involved in ascospore biosynthesis|ERK/MAPK cascade involved in ascospore formation|mitogen-activated protein kinase cascade involved in ascospore formation|MAP kinase cascade involved in ascospore biosynthesis|MAP kinase kinase kinase cascade involved in ascospore biosynthesis|MAPKKK cascade involved in ascospore biosynthesis|MAPK cascade involved in ascospore biosynthesis|MAPK signal transduction involved in ascospore biosynthesis|MAPK signalling involved in ascospore formation|MAPK signal transduction involved in ascospore formation|MAPK signaling involved in ascospore formation|MAPK signaling involved in ascospore biosynthesis|MAPKKK cascade involved in ascospore formation|ERK/MAPK cascade involved in ascospore biosynthesis http://purl.obolibrary.org/obo/GO_1903695 SO:0000409 biolink:SequenceFeature binding_site A biological_region of sequence that, in the molecule, interacts selectively and non-covalently with other molecules. A region on the surface of a molecule that may interact with another molecule. When applied to polypeptides: Amino acids involved in binding or interactions. It can also apply to an amino acid bond which is represented by the positions of the two flanking amino acids. http://en.wikipedia.org/wiki/Binding_site go-plus.json binding site|binding_or_interaction_site|INSDC_feature:misc_binding|site http://purl.obolibrary.org/obo/SO_0000409 SOFA|biosapiens GO:0097428 biolink:BiologicalProcess protein maturation by iron-sulfur cluster transfer The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0097428 GO:0097427 biolink:CellularComponent microtubule bundle An arrangement of closely apposed microtubules running parallel to each other. NIF_Subcellular:sao1872343973 go-plus.json microtubule fascicle http://purl.obolibrary.org/obo/GO_0097427 GO:0097429 biolink:MolecularActivity amino acid ligation activity by nonribosomal peptide synthase Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase. go-plus.json http://purl.obolibrary.org/obo/GO_0097429 GO:0097424 biolink:CellularComponent nucleolus-associated heterochromatin Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus. NIF_Subcellular:sao1210952635 go-plus.json http://purl.obolibrary.org/obo/GO_0097424 GO:0097423 biolink:CellularComponent mitochondrion-associated adherens complex An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans. NIF_Subcellular:sao1933817066 go-plus.json MAC|mitochondrial adhaerens complex http://purl.obolibrary.org/obo/GO_0097423 GO:0097426 biolink:CellularComponent glial filament An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes. NIF_Subcellular:sao1863852493 go-plus.json http://purl.obolibrary.org/obo/GO_0097426 GO:0097425 biolink:CellularComponent obsolete smooth endoplasmic reticulum part OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER). NIF_Subcellular:sao184202831 go-plus.json SER subcomponent http://purl.obolibrary.org/obo/GO_0097425 gocheck_do_not_annotate CHEBI:73136 biolink:ChemicalSubstance EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73136 CHEBI:87781 biolink:ChemicalSubstance (3S)-3-hydroxyoleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87781 CHEBI:38808 biolink:ChemicalSubstance calcium channel modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_38808 CHEBI:38807 biolink:ChemicalSubstance calcium channel agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_38807 CHEBI:87783 biolink:ChemicalSubstance (25R)-3beta-hydroxycholest-5-en-7-one-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87783 CHEBI:87785 biolink:ChemicalSubstance beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87785 chebi_ph7_3 CHEBI:87787 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNac-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87787 chebi_ph7_3 CHEBI:38809 biolink:ChemicalSubstance ryanodine receptor modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_38809 CHEBI:87789 biolink:ChemicalSubstance beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87789 chebi_ph7_3 CHEBI:87788 biolink:ChemicalSubstance beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87788 chebi_ph7_3 CHEBI:73131 biolink:ChemicalSubstance 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73131 CHEBI:73134 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73134 CHEBI:73148 biolink:ChemicalSubstance (S)-4-hydroxy-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73148 UBERON:0035295 biolink:AnatomicalEntity left ear The organ of hearing located on the left side of the head[ncit,modified]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035295 CHEBI:38818 biolink:ChemicalSubstance N-methylcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38818 CHEBI:87772 biolink:ChemicalSubstance (4Z)-2-oxohept-4-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87772 CHEBI:87771 biolink:ChemicalSubstance (2Z,4Z)-2-hydroxyhepta-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87771 CHEBI:87774 biolink:ChemicalSubstance 16alpha-hydroxydehydroepiandrosterone 3-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87774 CHEBI:87773 biolink:ChemicalSubstance (S)-4-hydroxy-2-oxoheptanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87773 PR:000011116 biolink:Protein NEDD8 protein A protein that is a translation product of the human NEDD8 gene or a 1:1 ortholog thereof. go-plus.json neddylin|NEDD-8|NEDD8|neural precursor cell expressed developmentally down-regulated protein 8|ubiquitin-like protein Nedd8 http://purl.obolibrary.org/obo/PR_000011116 CHEBI:73142 biolink:ChemicalSubstance (S)-4-hydroxy-2-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73142 chebi_ph7_3 CHEBI:73143 biolink:ChemicalSubstance (S)-4-hydroxy-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73143 chebi_ph7_3 CHEBI:73145 biolink:ChemicalSubstance N-hexadecanoylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73145 GO:0048406 biolink:MolecularActivity nerve growth factor binding Binding to nerve growth factor (NGF). go-plus.json NGF binding|neurotrophin TRKA receptor activity|beta-nerve growth factor binding http://purl.obolibrary.org/obo/GO_0048406 UBERON:0011298 biolink:AnatomicalEntity submucosa of uterine tube The submucous layer of the wall of the uterine tube. go-plus.json tela submucosa tubae uterinae|submucous layer of uterine tube|submucosa of fallopian tube|uterine submucosa http://purl.obolibrary.org/obo/UBERON_0011298 GO:0048405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048405 GO:0048404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048404 GO:0048403 biolink:MolecularActivity brain-derived neurotrophic factor binding Binding to brain-derived neurotrophic factor. go-plus.json neurotrophin TRKB receptor activity|BDNF binding http://purl.obolibrary.org/obo/GO_0048403 GO:0048402 biolink:BiologicalProcess intermediate mesoderm structural organization The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure. go-plus.json intermediate mesoderm structural organisation http://purl.obolibrary.org/obo/GO_0048402 GO:0048401 biolink:BiologicalProcess negative regulation of intermediate mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification. go-plus.json inhibition of intermediate mesodermal cell fate specification|down regulation of intermediate mesodermal cell fate specification|downregulation of intermediate mesodermal cell fate specification|down-regulation of intermediate mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048401 GO:0048400 biolink:BiologicalProcess positive regulation of intermediate mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification. go-plus.json up-regulation of intermediate mesodermal cell fate specification|upregulation of intermediate mesodermal cell fate specification|up regulation of intermediate mesodermal cell fate specification|activation of intermediate mesodermal cell fate specification|stimulation of intermediate mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0048400 UBERON:0011299 biolink:AnatomicalEntity white matter of telencephalon A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum. go-plus.json telencephalic tract/commissure|telencephalic tracts|telencephalic white matter|predominantly white regional part of telencephalon http://purl.obolibrary.org/obo/UBERON_0011299 GO:0048409 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048409 GO:0048408 biolink:MolecularActivity epidermal growth factor binding Binding to epidermal growth factor. go-plus.json EGF binding http://purl.obolibrary.org/obo/GO_0048408 GO:0048407 biolink:MolecularActivity platelet-derived growth factor binding Binding to platelet-derived growth factor. go-plus.json PDGF binding http://purl.obolibrary.org/obo/GO_0048407 CHEBI:73151 biolink:ChemicalSubstance (S)-4-hydroxy-2-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73151 CHEBI:73152 biolink:ChemicalSubstance 2,6-dimethyldeca-2,4,6,8-tetraenedial go-plus.json http://purl.obolibrary.org/obo/CHEBI_73152 chebi_ph7_3 CHEBI:73155 biolink:ChemicalSubstance trienoic fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73155 CHEBI:87792 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87792 chebi_ph7_3 GO:0048417 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048417 CHEBI:87791 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87791 chebi_ph7_3 GO:0048416 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048416 GO:0048415 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048415 GO:0048414 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048414 GO:0048413 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048413 GO:0048412 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048412 GO:0048411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048411 SO:3000000 biolink:SequenceFeature gene_segment A gene component region which acts as a recombinational unit of a gene whose functional form is generated through somatic recombination. go-plus.json gene segment http://purl.obolibrary.org/obo/SO_3000000 GO:0048410 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048410 GO:0048419 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048419 GO:0048418 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048418 GO:0048420 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048420 CHEBI:167550 biolink:ChemicalSubstance dodecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_167550 GO:0048428 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048428 GO:0048427 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048427 GO:0048426 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048426 CHEBI:167559 biolink:ChemicalSubstance glycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_167559 GO:0048425 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048425 GO:0048424 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048424 GO:0048423 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048423 GO:0048422 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048422 CHEBI:167555 biolink:ChemicalSubstance 2-dodecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_167555 GO:0048421 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048421 GO:0048429 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048429 GO:0048431 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048431 GO:0048430 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048430 GO:0048439 biolink:BiologicalProcess flower morphogenesis The process in which the anatomical structures of the flower are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048439 GO:0048438 biolink:BiologicalProcess floral whorl development The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant. go-plus.json collective phyllome structure development http://purl.obolibrary.org/obo/GO_0048438 GO:0048437 biolink:BiologicalProcess floral organ development The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048437 GO:0048436 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048436 GO:0048435 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048435 GO:0048434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048434 GO:0048433 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048433 GO:0048432 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048432 CHEBI:73180 biolink:ChemicalSubstance beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_73180 chebi_ph7_3 CHEBI:73182 biolink:ChemicalSubstance plant activator go-plus.json http://purl.obolibrary.org/obo/CHEBI_73182 CHEBI:73181 biolink:ChemicalSubstance EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_73181 CHEBI:73184 biolink:ChemicalSubstance 2-amino-4-hydroxypteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73184 chebi_ph7_3 CHEBI:73183 biolink:ChemicalSubstance 1-(5-phospho-beta-D-ribosyl)-ATP(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73183 chebi_ph7_3 CHEBI:73186 biolink:ChemicalSubstance 2,4-dihydroxypteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73186 chebi_ph7_3 GO:0048442 biolink:BiologicalProcess sepal development The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048442 GO:0048441 biolink:BiologicalProcess petal development The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048441 GO:1903609 biolink:BiologicalProcess negative regulation of inward rectifier potassium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity. go-plus.json negative regulation of Kir channel activity|down-regulation of Kir channel activity|down regulation of inward rectifier potassium channel activity|downregulation of Kir channel activity|downregulation of inward rectifier potassium channel activity|down regulation of Kir channel activity|inhibition of Kir channel activity|down-regulation of inward rectifier potassium channel activity|inhibition of inward rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_1903609 GO:0048440 biolink:BiologicalProcess carpel development The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style. go-plus.json http://purl.obolibrary.org/obo/GO_0048440 GO:1903608 biolink:BiologicalProcess protein localization to cytoplasmic stress granule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule. go-plus.json protein localisation in cytoplasmic stress granule|protein localization in cytoplasmic stress granule|protein localization to stress granule|protein localisation to cytoplasmic stress granule http://purl.obolibrary.org/obo/GO_1903608 GO:1903607 biolink:BiologicalProcess cytochrome c biosynthetic process The chemical reactions and pathways resulting in the formation of cytochrome c. go-plus.json cytochrome c anabolism|cytochrome c synthesis|cytochrome c formation|cytochrome c biosynthesis http://purl.obolibrary.org/obo/GO_1903607 GO:1903606 biolink:BiologicalProcess cytochrome c metabolic process The chemical reactions and pathways involving cytochrome c. go-plus.json cytochrome c metabolism http://purl.obolibrary.org/obo/GO_1903606 GO:1903605 biolink:BiologicalProcess cytochrome biosynthetic process The chemical reactions and pathways resulting in the formation of a cytochrome. go-plus.json cytochrome anabolism|cytochrome biosynthesis|cytochrome synthesis|cytochrome formation http://purl.obolibrary.org/obo/GO_1903605 GO:1903604 biolink:BiologicalProcess cytochrome metabolic process The chemical reactions and pathways involving a cytochrome. go-plus.json cytochrome metabolism http://purl.obolibrary.org/obo/GO_1903604 GO:1903603 biolink:BiologicalProcess thermospermine biosynthetic process The chemical reactions and pathways resulting in the formation of thermospermine. go-plus.json thermospermine synthesis|thermospermine formation|thermospermine biosynthesis|thermospermine anabolism http://purl.obolibrary.org/obo/GO_1903603 GO:0048449 biolink:BiologicalProcess floral organ formation The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048449 GO:1903602 biolink:BiologicalProcess thermospermine catabolic process The chemical reactions and pathways resulting in the breakdown of thermospermine. go-plus.json thermospermine catabolism|thermospermine degradation|thermospermine breakdown http://purl.obolibrary.org/obo/GO_1903602 UBERON:0035267 biolink:AnatomicalEntity neck of gallbladder The narrowest portion of the gallbladder and distal to the cystic duct. go-plus.json gallbladder neck|cervix of gallbladder http://purl.obolibrary.org/obo/UBERON_0035267 GO:1903601 biolink:BiologicalProcess thermospermine metabolic process The chemical reactions and pathways involving thermospermine. go-plus.json thermospermine metabolism http://purl.obolibrary.org/obo/GO_1903601 GO:0048448 biolink:BiologicalProcess stamen morphogenesis The process in which the anatomical structures of the stamen are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048448 GO:1903600 biolink:CellularComponent glutaminase complex A protein complex which is capable of glutaminase activity. go-plus.json Sno1p-Snz1p http://purl.obolibrary.org/obo/GO_1903600 GO:0048447 biolink:BiologicalProcess sepal morphogenesis The process in which the anatomical structures of the sepal are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048447 GO:0048446 biolink:BiologicalProcess petal morphogenesis The process in which the anatomical structures of the petal are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048446 GO:0048445 biolink:BiologicalProcess carpel morphogenesis The process in which the anatomical structures of the carpel are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048445 GO:0048444 biolink:BiologicalProcess floral organ morphogenesis The process in which the anatomical structures of the floral organ are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048444 GO:0048443 biolink:BiologicalProcess stamen development The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048443 CHEBI:73191 biolink:ChemicalSubstance abscisic acid receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_73191 CHEBI:73194 biolink:ChemicalSubstance 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73194 chebi_ph7_3 GO:0048453 biolink:BiologicalProcess sepal formation The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048453 GO:0048452 biolink:BiologicalProcess petal structural organization The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure. go-plus.json petal structural organisation http://purl.obolibrary.org/obo/GO_0048452 GO:0048451 biolink:BiologicalProcess petal formation The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048451 GO:1903619 biolink:BiologicalProcess negative regulation of transdifferentiation Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation. go-plus.json down-regulation of transdifferentiation|downregulation of transdifferentiation|down regulation of transdifferentiation|inhibition of transdifferentiation http://purl.obolibrary.org/obo/GO_1903619 GO:0048450 biolink:BiologicalProcess floral organ structural organization The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure. go-plus.json floral organ structural organisation http://purl.obolibrary.org/obo/GO_0048450 GO:1903618 biolink:BiologicalProcess regulation of transdifferentiation Any process that modulates the frequency, rate or extent of transdifferentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1903618 GO:1903617 biolink:BiologicalProcess positive regulation of mitotic cytokinesis, site selection Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, site selection. go-plus.json http://purl.obolibrary.org/obo/GO_1903617 GO:1903616 biolink:BiologicalProcess obsolete MAPK cascade involved in axon regeneration OBSOLETE. Any MAPK cascade that is involved in axon regeneration. go-plus.json MAPK signalling involved in axon regeneration|MAPK signal transduction involved in axon regeneration|MAPK signaling involved in axon regeneration|MAPKKK cascade involved in axon regeneration|MAPKKK cascade during sporulation involved in axon regeneration|MAP kinase kinase kinase cascade involved in axon regeneration|MAP kinase cascade involved in axon regeneration|ERK/MAPK cascade involved in axon regeneration|mitogen-activated protein kinase cascade involved in axon regeneration http://purl.obolibrary.org/obo/GO_1903616 GO:1903615 biolink:BiologicalProcess positive regulation of protein tyrosine phosphatase activity Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity. go-plus.json upregulation of tyrosine O-phosphate phosphatase activity|upregulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of protein phosphotyrosine phosphatase activity|upregulation of phosphotyrosine protein phosphatase activity|up-regulation of PTPase activity|upregulation of phosphotyrosine histone phosphatase activity|positive regulation of phosphotyrosylprotein phosphatase activity|up-regulation of protein-tyrosine-phosphate phosphohydrolase activity|activation of protein-tyrosine-phosphate phosphohydrolase activity|up-regulation of PPT-phosphatase activity|up regulation of phosphotyrosylprotein phosphatase activity|upregulation of [phosphotyrosine]protein phosphatase activity|activation of PPT-phosphatase activity|up-regulation of tyrosylprotein phosphatase activity|up regulation of protein-tyrosine-phosphatase activity|up regulation of protein tyrosine phosphatase activity|up-regulation of phosphotyrosine phosphatase activity|positive regulation of PTP-phosphatase activity|activation of phosphotyrosine phosphatase activity|activation of protein-tyrosine-phosphatase activity|positive regulation of protein-tyrosine-phosphatase activity|activation of protein tyrosine phosphatase activity|up regulation of PTP-phosphatase activity|up regulation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of tyrosine O-phosphate phosphatase activity|up-regulation of phosphotyrosine protein phosphatase activity|up-regulation of protein phosphotyrosine phosphatase activity|activation of phosphoprotein phosphatase (phosphotyrosine) activity|up-regulation of phosphotyrosine histone phosphatase activity|activation of protein phosphotyrosine phosphatase activity|activation of tyrosine O-phosphate phosphatase activity|positive regulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of PTPase activity|activation of phosphotyrosine protein phosphatase activity|positive regulation of tyrosine O-phosphate phosphatase activity|activation of phosphotyrosine histone phosphatase activity|upregulation of phosphotyrosylprotein phosphatase activity|positive regulation of protein-tyrosine-phosphate phosphohydrolase activity|up regulation of [phosphotyrosine]protein phosphatase activity|upregulation of tyrosylprotein phosphatase activity|positive regulation of PPT-phosphatase activity|up regulation of protein-tyrosine-phosphate phosphohydrolase activity|activation of [phosphotyrosine]protein phosphatase activity|up regulation of PPT-phosphatase activity|positive regulation of [phosphotyrosine]protein phosphatase activity|positive regulation of phosphotyrosine phosphatase activity|up-regulation of protein-tyrosine-phosphatase activity|upregulation of PTP-phosphatase activity|up-regulation of protein tyrosine phosphatase activity|up regulation of phosphotyrosine phosphatase activity|positive regulation of protein phosphotyrosine phosphatase activity|positive regulation of phosphotyrosine protein phosphatase activity|up regulation of PTPase activity|up-regulation of tyrosine O-phosphate phosphatase activity|positive regulation of phosphotyrosine histone phosphatase activity|up-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of protein phosphotyrosine phosphatase activity|positive regulation of PTPase activity|activation of PTPase activity|up regulation of phosphotyrosine protein phosphatase activity|up-regulation of phosphotyrosylprotein phosphatase activity|up regulation of phosphotyrosine histone phosphatase activity|activation of phosphotyrosylprotein phosphatase activity|up regulation of tyrosylprotein phosphatase activity|upregulation of protein-tyrosine-phosphate phosphohydrolase activity|upregulation of PPT-phosphatase activity|positive regulation of tyrosylprotein phosphatase activity|activation of tyrosylprotein phosphatase activity|up-regulation of [phosphotyrosine]protein phosphatase activity|upregulation of protein-tyrosine-phosphatase activity|up-regulation of PTP-phosphatase activity|upregulation of protein tyrosine phosphatase activity|activation of PTP-phosphatase activity|upregulation of phosphotyrosine phosphatase activity http://purl.obolibrary.org/obo/GO_1903615 GO:1903614 biolink:BiologicalProcess negative regulation of protein tyrosine phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity. go-plus.json down regulation of protein tyrosine phosphatase activity|down-regulation of tyrosylprotein phosphatase activity|down regulation of phosphotyrosine histone phosphatase activity|negative regulation of tyrosylprotein phosphatase activity|down regulation of protein-tyrosine-phosphatase activity|inhibition of phosphotyrosine protein phosphatase activity|inhibition of protein phosphotyrosine phosphatase activity|inhibition of phosphotyrosine histone phosphatase activity|down regulation of tyrosine O-phosphate phosphatase activity|down regulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of PTPase activity|down-regulation of PTP-phosphatase activity|downregulation of protein tyrosine phosphatase activity|downregulation of protein-tyrosine-phosphatase activity|negative regulation of PTP-phosphatase activity|downregulation of tyrosine O-phosphate phosphatase activity|downregulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of tyrosylprotein phosphatase activity|downregulation of phosphotyrosylprotein phosphatase activity|down regulation of [phosphotyrosine]protein phosphatase activity|negative regulation of protein-tyrosine-phosphate phosphohydrolase activity|down-regulation of protein-tyrosine-phosphate phosphohydrolase activity|down regulation of phosphotyrosylprotein phosphatase activity|down-regulation of PPT-phosphatase activity|negative regulation of PPT-phosphatase activity|downregulation of PTP-phosphatase activity|downregulation of [phosphotyrosine]protein phosphatase activity|down-regulation of protein tyrosine phosphatase activity|negative regulation of protein-tyrosine-phosphatase activity|down-regulation of protein-tyrosine-phosphatase activity|inhibition of phosphotyrosylprotein phosphatase activity|down regulation of PTPase activity|negative regulation of phosphotyrosine phosphatase activity|down-regulation of phosphotyrosine phosphatase activity|down-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|negative regulation of phosphoprotein phosphatase (phosphotyrosine) activity|down-regulation of tyrosine O-phosphate phosphatase activity|negative regulation of tyrosine O-phosphate phosphatase activity|down regulation of PTP-phosphatase activity|negative regulation of phosphotyrosine protein phosphatase activity|down-regulation of phosphotyrosine protein phosphatase activity|negative regulation of protein phosphotyrosine phosphatase activity|down-regulation of protein phosphotyrosine phosphatase activity|downregulation of PTPase activity|down-regulation of phosphotyrosine histone phosphatase activity|inhibition of PTP-phosphatase activity|negative regulation of phosphotyrosine histone phosphatase activity|down regulation of tyrosylprotein phosphatase activity|inhibition of protein-tyrosine-phosphatase activity|downregulation of protein-tyrosine-phosphate phosphohydrolase activity|inhibition of protein tyrosine phosphatase activity|downregulation of PPT-phosphatase activity|negative regulation of [phosphotyrosine]protein phosphatase activity|down-regulation of [phosphotyrosine]protein phosphatase activity|inhibition of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of tyrosine O-phosphate phosphatase activity|downregulation of tyrosylprotein phosphatase activity|downregulation of phosphotyrosine phosphatase activity|down regulation of protein-tyrosine-phosphate phosphohydrolase activity|down regulation of PPT-phosphatase activity|inhibition of protein-tyrosine-phosphate phosphohydrolase activity|downregulation of protein phosphotyrosine phosphatase activity|inhibition of PPT-phosphatase activity|downregulation of phosphotyrosine protein phosphatase activity|negative regulation of PTPase activity|downregulation of phosphotyrosine histone phosphatase activity|down regulation of phosphotyrosine phosphatase activity|down-regulation of PTPase activity|inhibition of [phosphotyrosine]protein phosphatase activity|inhibition of phosphotyrosine phosphatase activity|down regulation of protein phosphotyrosine phosphatase activity|negative regulation of phosphotyrosylprotein phosphatase activity|down regulation of phosphotyrosine protein phosphatase activity|down-regulation of phosphotyrosylprotein phosphatase activity http://purl.obolibrary.org/obo/GO_1903614 GO:1903613 biolink:BiologicalProcess regulation of protein tyrosine phosphatase activity Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity. go-plus.json regulation of protein-tyrosine-phosphatase activity|regulation of phosphoprotein phosphatase (phosphotyrosine) activity|regulation of tyrosine O-phosphate phosphatase activity|regulation of phosphotyrosylprotein phosphatase activity|regulation of [phosphotyrosine]protein phosphatase activity|regulation of PTP-phosphatase activity|regulation of PTPase activity|regulation of tyrosylprotein phosphatase activity|regulation of protein-tyrosine-phosphate phosphohydrolase activity|regulation of PPT-phosphatase activity|regulation of phosphotyrosine phosphatase activity|regulation of phosphotyrosine protein phosphatase activity|regulation of protein phosphotyrosine phosphatase activity|regulation of phosphotyrosine histone phosphatase activity http://purl.obolibrary.org/obo/GO_1903613 GO:0048459 biolink:BiologicalProcess floral whorl structural organization The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure. go-plus.json floral whorl structural organisation http://purl.obolibrary.org/obo/GO_0048459 GO:1903612 biolink:BiologicalProcess positive regulation of calcium-dependent ATPase activity Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity. go-plus.json up regulation of calcium-dependent ATPase activity|activation of calcium-dependent ATPase activity|up-regulation of calcium-dependent ATPase activity|upregulation of calcium-dependent ATPase activity http://purl.obolibrary.org/obo/GO_1903612 GO:1903611 biolink:BiologicalProcess negative regulation of calcium-dependent ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity. go-plus.json downregulation of calcium-dependent ATPase activity|down-regulation of calcium-dependent ATPase activity|inhibition of calcium-dependent ATPase activity|down regulation of calcium-dependent ATPase activity http://purl.obolibrary.org/obo/GO_1903611 GO:0048458 biolink:BiologicalProcess floral whorl formation The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048458 GO:1903610 biolink:BiologicalProcess regulation of calcium-dependent ATPase activity Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903610 GO:0048457 biolink:BiologicalProcess floral whorl morphogenesis The process in which the anatomical structures of the floral whorl are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048457 GO:0048456 biolink:BiologicalProcess stamen structural organization The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure. go-plus.json stamen structural organisation http://purl.obolibrary.org/obo/GO_0048456 GO:0048455 biolink:BiologicalProcess stamen formation The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0048455 GO:0048454 biolink:BiologicalProcess sepal structural organization The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure. go-plus.json sepal structural organisation http://purl.obolibrary.org/obo/GO_0048454 CHEBI:24129 biolink:ChemicalSubstance furans go-plus.json http://purl.obolibrary.org/obo/CHEBI_24129 UBERON:0001549 biolink:AnatomicalEntity dorsal metatarsal vein The dorsal metatarsal veins are veins which drain the metatarsus of the foot. [WP,unvetted]. go-plus.json venae metatarsales dorsales|metatarsal vein http://purl.obolibrary.org/obo/UBERON_0001549 CHEBI:24128 biolink:ChemicalSubstance furanocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_24128 CHEBI:24127 biolink:ChemicalSubstance fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24127 CHEBI:63730 biolink:ChemicalSubstance 7-methylguanosine 5'-diphosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63730 CHEBI:24121 biolink:ChemicalSubstance fucosyl oligoglycosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24121 CHEBI:87701 biolink:ChemicalSubstance (2E,5Z)-tetradecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87701 chebi_ph7_3 CHEBI:38767 biolink:ChemicalSubstance benzothiophenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38767 CHEBI:63734 biolink:ChemicalSubstance ketone hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63734 chebi_ph7_3 CHEBI:63733 biolink:ChemicalSubstance aldehyde hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63733 chebi_ph7_3 CHEBI:87700 biolink:ChemicalSubstance (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87700 chebi_ph7_3 CHEBI:63732 biolink:ChemicalSubstance 1,1-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63732 CHEBI:87702 biolink:ChemicalSubstance (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87702 chebi_ph7_3 CHEBI:63731 biolink:ChemicalSubstance 9beta-pimara-7,15-dien-19-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63731 CHEBI:87705 biolink:ChemicalSubstance (3S,5Z)-3-hydroxytetradec-5-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87705 chebi_ph7_3 CHEBI:63738 biolink:ChemicalSubstance diadenosyl tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63738 UBERON:8300002 biolink:AnatomicalEntity left forelimb A forelimb that is on the left side of a pectoral complex. go-plus.json http://purl.obolibrary.org/obo/UBERON_8300002 CHEBI:63737 biolink:ChemicalSubstance diadenosyl pentaphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63737 UBERON:8300001 biolink:AnatomicalEntity right forelimb A forelimb that is on the right side of a pectoral complex. go-plus.json http://purl.obolibrary.org/obo/UBERON_8300001 CHEBI:87704 biolink:ChemicalSubstance 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87704 chebi_ph7_3 CHEBI:87707 biolink:ChemicalSubstance (5Z)-3-oxotetradecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87707 chebi_ph7_3 UBERON:8300004 biolink:AnatomicalEntity left hindlimb A hindlimb that is on the left side of a pelvic complex. go-plus.json http://purl.obolibrary.org/obo/UBERON_8300004 CHEBI:63736 biolink:ChemicalSubstance diadenosyl hexaphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63736 CHEBI:63735 biolink:ChemicalSubstance (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63735 UBERON:8300003 biolink:AnatomicalEntity right hindlimb A hindlimb that is on the right side of a pelvic complex. go-plus.json http://purl.obolibrary.org/obo/UBERON_8300003 UBERON:0001554 biolink:AnatomicalEntity skin of hip A zone of skin that is part of a hip region. go-plus.json zone of skin of regio coxae|hip skin|hip region zone of skin|regio coxae zone of skin|hip zone of skin|zone of skin of hip region|zone of skin of hip http://purl.obolibrary.org/obo/UBERON_0001554 NCBITaxon:71139 biolink:OrganismalEntity Eucalyptus grandis go-plus.json rose gum http://purl.obolibrary.org/obo/NCBITaxon_71139 UBERON:0001556 biolink:AnatomicalEntity lower urinary tract Subdivision of urinary system which consists of the urinary bladder and the urethra. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001556 UBERON:0001555 biolink:AnatomicalEntity digestive tract A tube extending from the mouth to the anus. go-plus.json digestive tube|alimentary canal|digestive canal|alimentary tract|enteric tract|gut|gut tube http://purl.obolibrary.org/obo/UBERON_0001555 CHEBI:63739 biolink:ChemicalSubstance diadenosyl triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63739 PR:000001946 biolink:Protein tumor necrosis factor ligand superfamily member 10/11 A protein with core architecture consisting of a fairly small cytoplasmic region, a transmembrane domain, and an extracellular domain containing a TNF(Tumour Necrosis Factor) family domain (Pfam:PF00229). go-plus.json http://purl.obolibrary.org/obo/PR_000001946 CHEBI:38763 biolink:ChemicalSubstance chromanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38763 UBERON:0025525 biolink:AnatomicalEntity motor system The part of the central nervous system that is involved with movement. go-plus.json motor system http://purl.obolibrary.org/obo/UBERON_0025525 CHEBI:38762 biolink:ChemicalSubstance isochromanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38762 CHEBI:38761 biolink:ChemicalSubstance isochromenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38761 CHEBI:38760 biolink:ChemicalSubstance mellein go-plus.json http://purl.obolibrary.org/obo/CHEBI_38760 chebi_ph7_3 UBERON:0001536 biolink:AnatomicalEntity left common carotid artery plus branches The leftmost of the two common carotid arteries, originating from the aortic arch in the thorax. go-plus.json left common carotid artery|left common carotid artery|trunk of left common carotid tree http://purl.obolibrary.org/obo/UBERON_0001536 CHEBI:24138 biolink:ChemicalSubstance galactaric acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24138 CHEBI:63741 biolink:ChemicalSubstance 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63741 CHEBI:63740 biolink:ChemicalSubstance P(1),P(6)-bis(5'-adenosyl)hexaphosphate(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63740 chebi_ph7_3 CHEBI:38778 biolink:ChemicalSubstance triazinanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38778 CHEBI:38777 biolink:ChemicalSubstance azetidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38777 CHEBI:63743 biolink:ChemicalSubstance dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63743 CHEBI:63742 biolink:ChemicalSubstance (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63742 CHEBI:38775 biolink:ChemicalSubstance monohydroxyquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_38775 CHEBI:63749 biolink:ChemicalSubstance (+)-artemisinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63749 PR:000001951 biolink:Protein tumor necrosis factor receptor superfamily member 10A/B A death receptor with core architecture consisting of a signal sequence, an extracellular region containing three TNFR/NGFR cysteine-rich region domains (Pfam:PF00020), a transmembrane region, and an intracellular region containing a Death domain (Pfam:PF00531). There are two genes in human, TNFRSF10A and TNFRSF10B, more closely related to each other than to mouse TNFRSF10B. go-plus.json http://purl.obolibrary.org/obo/PR_000001951 CHEBI:63746 biolink:ChemicalSubstance TRIBOA go-plus.json http://purl.obolibrary.org/obo/CHEBI_63746 chebi_ph7_3 CHEBI:38779 biolink:ChemicalSubstance 1,3,5-triazinanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38779 UBERON:0001543 biolink:AnatomicalEntity popliteal lymph node the lymph nodes which drain the legs; contained in the popliteal fossa go-plus.json popliteal lymph node|popliteal lymph glands|popliteal glands http://purl.obolibrary.org/obo/UBERON_0001543 CHEBI:38774 biolink:ChemicalSubstance hydroxyquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_38774 CHEBI:38773 biolink:ChemicalSubstance quinolinemonocarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38773 UBERON:0025533 biolink:AnatomicalEntity proprioceptive system The sensory system for the sense of proprioception. go-plus.json proprioceptive system http://purl.obolibrary.org/obo/UBERON_0025533 UBERON:0001529 biolink:AnatomicalEntity brachiocephalic artery the short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery go-plus.json innominate artery|truncus brachiocephalicus|truncus brachiocephalicus|innominate|brachiocephalic trunk http://purl.obolibrary.org/obo/UBERON_0001529 CHEBI:24103 biolink:ChemicalSubstance fructosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24103 CHEBI:24108 biolink:ChemicalSubstance fructosylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24108 CHEBI:63750 biolink:ChemicalSubstance (5S,9S,10S,13E)-labda-7,13-dien-15-yl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63750 CHEBI:38745 biolink:ChemicalSubstance pentahydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38745 CHEBI:38744 biolink:ChemicalSubstance hexahydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38744 CHEBI:38742 biolink:ChemicalSubstance tetrahydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38742 CHEBI:38749 biolink:ChemicalSubstance dihydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38749 CHEBI:38748 biolink:ChemicalSubstance monohydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38748 CHEBI:38747 biolink:ChemicalSubstance taxifolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38747 chebi_ph7_3 CHEBI:87728 biolink:ChemicalSubstance isolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87728 chebi_ph7_3 UBERON:0001532 biolink:AnatomicalEntity internal carotid artery A terminal branch of the left or right common carotid artery which supplies oxygenated blood to the brain and eyes[MP] go-plus.json arteria carotis interna|internal carotid|ICA|cranial carotid artery http://purl.obolibrary.org/obo/UBERON_0001532 UBERON:0001531 biolink:AnatomicalEntity right common carotid artery plus branches The rightmost of the two common carotid arteries, originating from in the neck from the brachiocephalic trunk. go-plus.json right common carotid artery|right common carotid artery|trunk of right common carotid tree http://purl.obolibrary.org/obo/UBERON_0001531 UBERON:0001534 biolink:AnatomicalEntity right subclavian artery The subclavian artery that supplies the right pectoral appendage go-plus.json arteria subclavia dextra http://purl.obolibrary.org/obo/UBERON_0001534 UBERON:0001533 biolink:AnatomicalEntity subclavian artery One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta go-plus.json pectoral artery|arterial tree of upper limb|subclavian arterial tree|PA|arteria subclavia|arteria subclavia http://purl.obolibrary.org/obo/UBERON_0001533 CHEBI:24109 biolink:ChemicalSubstance fructosyllysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24109 CHEBI:38741 biolink:ChemicalSubstance isoflavanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_38741 chebi_ph7_3 CHEBI:38740 biolink:ChemicalSubstance isoflavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_38740 chebi_ph7_3 UBERON:0001530 biolink:AnatomicalEntity common carotid artery plus branches A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]. go-plus.json carotid artery|common carotid artery|trunk of common carotid tree|carotid artery system|a. carotis communis http://purl.obolibrary.org/obo/UBERON_0001530 PR:000001926 biolink:Protein semaphorin A protein with core architecture consisting of a signal sequence,a Sema domain (Pfam:PF01403), a Plexin repeat (Pfam:PF01437), and an Ig-like domain (Pfam:PF00047, Pfam:PF07686, or Pfam:PF07679). go-plus.json http://purl.obolibrary.org/obo/PR_000001926 UBERON:0001518 biolink:AnatomicalEntity skin of wrist A zone of skin that is part of a wrist [Automatically generated definition]. go-plus.json zone of skin of wrist|zone of skin of carpal region|wrist skin|carpal region zone of skin|wrist zone of skin http://purl.obolibrary.org/obo/UBERON_0001518 NCBITaxon:2864 biolink:OrganismalEntity Dinophyceae go-plus.json Chromophyta|Dinophyta|Pyrrophyta|Dinophycidae|algae|Pyrrhophyta|Dinoflagellata|dinoflagellates|dinoflagellates|dinophytes http://purl.obolibrary.org/obo/NCBITaxon_2864 CHEBI:24115 biolink:ChemicalSubstance fuconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24115 UBERON:0001517 biolink:AnatomicalEntity skin of elbow A zone of skin that is part of a elbow [Automatically generated definition]. go-plus.json elbow skin|elbow zone of skin|zone of skin of cubital region|zone of skin of elbow|cubital region zone of skin http://purl.obolibrary.org/obo/UBERON_0001517 CHEBI:24113 biolink:ChemicalSubstance fructuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24113 UBERON:0001519 biolink:AnatomicalEntity skin of manus A zone of skin that is part of a manus [Automatically generated definition]. go-plus.json skin of hand|hand skin|manus skin|skin of fore-paw http://purl.obolibrary.org/obo/UBERON_0001519 CHEBI:24112 biolink:ChemicalSubstance fructuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24112 CHEBI:24119 biolink:ChemicalSubstance fucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_24119 UBERON:0001514 biolink:AnatomicalEntity descending aorta The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]. go-plus.json aorta descendens|pars descendens aortae|pars descendens aortae http://purl.obolibrary.org/obo/UBERON_0001514 UBERON:0001513 biolink:AnatomicalEntity skin of pes A zone of skin that is part of a pes [Automatically generated definition]. go-plus.json skin of foot|foot skin|skin of hind-paw http://purl.obolibrary.org/obo/UBERON_0001513 UBERON:0001516 biolink:AnatomicalEntity abdominal aorta Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]. go-plus.json descending abdominal aorta|pars abdominalis aortae|aorta abdominalis|abdominal part of aorta|pars abdominalis aortae|abdominal part of aorta http://purl.obolibrary.org/obo/UBERON_0001516 UBERON:0001515 biolink:AnatomicalEntity thoracic aorta the part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest go-plus.json aorta thoracalis|pars thoracica aortae|thoracic part of aorta|aorta thoracica http://purl.obolibrary.org/obo/UBERON_0001515 CHEBI:24116 biolink:ChemicalSubstance fuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24116 CHEBI:87710 biolink:ChemicalSubstance (3E)-tetradecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87710 chebi_ph7_3 CHEBI:38756 biolink:ChemicalSubstance methoxyisoflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38756 CL:1001434 biolink:Cell olfactory bulb interneuron A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons go-plus.json http://purl.obolibrary.org/obo/CL_1001434 CHEBI:87712 biolink:ChemicalSubstance (2E,4E)-tetradecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87712 chebi_ph7_3 CL:1001433 biolink:Cell epithelial cell of exocrine pancreas An epithelial cell of the exocrine pancreas. go-plus.json exocrine pancreas cell http://purl.obolibrary.org/obo/CL_1001433 CHEBI:38755 biolink:ChemicalSubstance hydroxyisoflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38755 CHEBI:38759 biolink:ChemicalSubstance isocoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38759 chebi_ph7_3 CHEBI:38758 biolink:ChemicalSubstance isocoumarins go-plus.json http://purl.obolibrary.org/obo/CHEBI_38758 CHEBI:87718 biolink:ChemicalSubstance (3S,7Z)-3-hydroxyhexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87718 chebi_ph7_3 CHEBI:87717 biolink:ChemicalSubstance (2E,7Z)-hexadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87717 chebi_ph7_3 CHEBI:38757 biolink:ChemicalSubstance isoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_38757 chebi_ph7_3 CHEBI:87719 biolink:ChemicalSubstance (7Z)-3-oxohexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87719 chebi_ph7_3 CHEBI:38751 biolink:ChemicalSubstance triamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38751 NCBITaxon:131567 biolink:OrganismalEntity cellular organisms go-plus.json biota http://purl.obolibrary.org/obo/NCBITaxon_131567 CHEBI:63778 biolink:ChemicalSubstance CMP-pseudaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63778 CHEBI:87747 biolink:ChemicalSubstance 7alpha-hydroxy-3-oxochol-4-en-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87747 chebi_ph7_3 UBERON:0001592 biolink:AnatomicalEntity bronchial vein The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]. go-plus.json bronchial venous tree http://purl.obolibrary.org/obo/UBERON_0001592 UBERON:0001591 biolink:AnatomicalEntity thymic vein A vein that drains blood from the thymus. go-plus.json vena thymica|venae thymicae|thymic tributary of brachiocephalic vein http://purl.obolibrary.org/obo/UBERON_0001591 CHEBI:63775 biolink:ChemicalSubstance 1,2-dioleoyl-3-beta-D-galactosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63775 chebi_ph7_3 CHEBI:87748 biolink:ChemicalSubstance 3-oxochola-4,6-dien-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87748 chebi_ph7_3 CHEBI:63779 biolink:ChemicalSubstance alpha-D-Gal-(1->2)-alpha-D-Glc-(1->3')-1,2-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63779 chebi_ph7_3 CHEBI:14750 biolink:ChemicalSubstance acetylacetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_14750 chebi_ph7_3 UBERON:0001593 biolink:AnatomicalEntity venous plexus A congregation of multiple veins. go-plus.json plexus venosus|venous network|rete venosum http://purl.obolibrary.org/obo/UBERON_0001593 UBERON:0001579 biolink:AnatomicalEntity olfactory nerve Nerve that carries information from the olfactory epithelium to the olfactory bulb[Butler and Hodos]. go-plus.json first cranial nerve|1n|olfactoria fila|nervus olfactorius|nerve I|fila olfactoria|cranial nerve I|olfactory fila|olfactory nerve [I]|CN-I|nervus olfactorius [i]|olfactory i nerve|olfactory I|nerve of smell http://purl.obolibrary.org/obo/UBERON_0001579 CHEBI:38739 biolink:ChemicalSubstance trihydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38739 CHEBI:87730 biolink:ChemicalSubstance 3beta,7alpha-dihydroxy-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87730 chebi_ph7_3 CHEBI:87731 biolink:ChemicalSubstance 7alpha-hydroxy-3-oxo-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87731 chebi_ph7_3 CHEBI:87734 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87734 chebi_ph7_3 CHEBI:63788 biolink:ChemicalSubstance alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3')-1,2-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63788 chebi_ph7_3 CHEBI:87733 biolink:ChemicalSubstance 3beta,12alpha-dihydroxy-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87733 chebi_ph7_3 CHEBI:87736 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87736 chebi_ph7_3 PR:000001991 biolink:Protein C-C motif chemokine 19 A C/C-C motif small inducible chemokine that is a translation product of the human CCL19 gene or a 1:1 ortholog thereof. go-plus.json macrophage inflammatory protein 3 beta|beta chemokine exodus-3|CK beta-11|MIP-3-beta|EBI1 ligand chemokine|MIP3B|ELC|SCYA19|epstein-Barr virus-induced molecule 1 ligand chemokine|small-inducible cytokine A19|CCL19 http://purl.obolibrary.org/obo/PR_000001991 CHEBI:63786 biolink:ChemicalSubstance beta-D-Glc-(1->6)-beta-D-Glc-(1->3')-1,2-diacylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63786 chebi_ph7_3 CHEBI:87735 biolink:ChemicalSubstance 3beta,7alpha,12alpha-trihydroxy-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87735 chebi_ph7_3 PR:000001993 biolink:Protein C-C motif chemokine 21 A C/C-C motif small inducible chemokine that is a translation product of the human CCL21 gene or a 1:1 ortholog thereof. go-plus.json CCL21|small-inducible cytokine A21c|secondary lymphoid-tissue chemokine|SLC|small-inducible cytokine A21b|small-inducible cytokine A21a|Scya21c|Scya21b|beta chemokine exodus-2|thymus-derived chemotactic agent 4|6Ckine|TCA4|Ccl21c|SCYA21|Ccl21b|small-inducible cytokine A21 http://purl.obolibrary.org/obo/PR_000001993 CHEBI:38738 biolink:ChemicalSubstance monomethoxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38738 UBERON:0001586 biolink:AnatomicalEntity internal jugular vein One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]. go-plus.json vena jugularis interna|internal jugular venous tree|internal jugular http://purl.obolibrary.org/obo/UBERON_0001586 UBERON:0001585 biolink:AnatomicalEntity anterior vena cava A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart. go-plus.json cranial vena cava|superior vena cava|vena maxima|precava|vena cava superior|superior caval vein http://purl.obolibrary.org/obo/UBERON_0001585 UBERON:0001584 biolink:AnatomicalEntity left subclavian artery The subclavian artery that supplies the left pectoral appendage go-plus.json arteria subclavia (sinistra) http://purl.obolibrary.org/obo/UBERON_0001584 CHEBI:73117 biolink:ChemicalSubstance 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73117 chebi_ph7_3 UBERON:0001568 biolink:AnatomicalEntity muscle of larynx The muscles associated with the larynx. go-plus.json musculi laryngeales|larynx muscle organ|laryngeal muscle|muscle organ of larynx|larynx muscle http://purl.obolibrary.org/obo/UBERON_0001568 GO:0048604 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048604 GO:0048603 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048603 GO:0048602 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048602 CHEBI:63790 biolink:ChemicalSubstance glyco-amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63790 GO:0048601 biolink:BiologicalProcess oocyte morphogenesis The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. go-plus.json oocyte morphogenesis during differentiation http://purl.obolibrary.org/obo/GO_0048601 CHEBI:38706 biolink:ChemicalSubstance pediculicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38706 CHEBI:63796 biolink:ChemicalSubstance N(alpha)-citryl-N(epsilon)-acetyl-N(epsilon)-hydroxylysine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63796 chebi_ph7_3 GO:0048600 biolink:BiologicalProcess oocyte fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0048600 CHEBI:63795 biolink:ChemicalSubstance all-trans-4-hydroxyretinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63795 CHEBI:63794 biolink:ChemicalSubstance retinoid X receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_63794 CHEBI:87765 biolink:ChemicalSubstance L-ribonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87765 CHEBI:87764 biolink:ChemicalSubstance N-docosanoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87764 CHEBI:38700 biolink:ChemicalSubstance organic sodium salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_38700 CHEBI:87769 biolink:ChemicalSubstance lithocholyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_87769 GO:0048609 biolink:BiologicalProcess multicellular organismal reproductive process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. go-plus.json reproductive process in a multicellular organism|organismal reproductive process http://purl.obolibrary.org/obo/GO_0048609 CHEBI:87768 biolink:ChemicalSubstance N-hexacosanoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87768 GO:0048608 biolink:BiologicalProcess reproductive structure development The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. go-plus.json http://purl.obolibrary.org/obo/GO_0048608 GO:0048607 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048607 GO:0048606 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048606 CHEBI:38702 biolink:ChemicalSubstance inorganic sodium salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_38702 GO:0048605 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048605 UBERON:0001576 biolink:AnatomicalEntity intrinsic muscle of tongue The intrinsic tongue muscles are an integral part of the tongue and completely contained within the tongue that are innervated by Cranial Nerve XII. go-plus.json intrinsic lingual muscle|intrinsic tongue muscle http://purl.obolibrary.org/obo/UBERON_0001576 UBERON:0001575 biolink:AnatomicalEntity extrinsic muscle of tongue A muscle organ that attaches the tongue to some other structure. go-plus.json extrinsic lingual muscle|extrinsic tongue muscle http://purl.obolibrary.org/obo/UBERON_0001575 UBERON:0001577 biolink:AnatomicalEntity facial muscle A muscle innervated by a facial nerve. go-plus.json facial muscle proper|cranial-facial muscle|muscle organ of face|musculi faciei|face muscle organ|facial muscle|muscle of facil expression|craniofacial muscle|muscles of facial expression|facial nerve muscle|muscle of face|mimetic muscles|facial nerve innervated muscle|cranio-facial muscle|face muscle http://purl.obolibrary.org/obo/UBERON_0001577 UBERON:0001572 biolink:AnatomicalEntity hyoglossus muscle A muscle that attaches to the hyopid bone and to the tongue and is innervated by cranial nerve XII go-plus.json hyoglossus|m. hyoglossus http://purl.obolibrary.org/obo/UBERON_0001572 UBERON:0001571 biolink:AnatomicalEntity genioglossus muscle Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue. go-plus.json musculus genioglossus|genioglossus|m. genioglossus http://purl.obolibrary.org/obo/UBERON_0001571 CHEBI:73110 biolink:ChemicalSubstance ganglioside GM1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73110 chebi_ph7_3 CHEBI:73126 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73126 CHEBI:73125 biolink:ChemicalSubstance 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73125 chebi_ph7_3 CHEBI:73127 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73127 UBERON:0001558 biolink:AnatomicalEntity lower respiratory tract The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified] go-plus.json lower respiratory system http://purl.obolibrary.org/obo/UBERON_0001558 UBERON:0001557 biolink:AnatomicalEntity upper respiratory tract The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001557 GO:0048615 biolink:BiologicalProcess embryonic anterior midgut (ectodermal) morphogenesis The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048615 GO:0048614 biolink:BiologicalProcess post-embryonic ectodermal digestive tract morphogenesis The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized. go-plus.json post-embryonic ectodermal gut morphogenesis http://purl.obolibrary.org/obo/GO_0048614 GO:0048613 biolink:BiologicalProcess embryonic ectodermal digestive tract morphogenesis The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized. go-plus.json embryonic ectodermal gut morphogenesis http://purl.obolibrary.org/obo/GO_0048613 GO:0048612 biolink:BiologicalProcess post-embryonic ectodermal digestive tract development The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure. go-plus.json post-embryonic ectodermal gut development http://purl.obolibrary.org/obo/GO_0048612 CHEBI:38717 biolink:ChemicalSubstance carboxylic acid trianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38717 GO:0048611 biolink:BiologicalProcess embryonic ectodermal digestive tract development The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure. go-plus.json embryonic ectodermal gut development http://purl.obolibrary.org/obo/GO_0048611 CHEBI:87751 biolink:ChemicalSubstance ocimene go-plus.json http://purl.obolibrary.org/obo/CHEBI_87751 GO:0048610 biolink:BiologicalProcess obsolete cellular process involved in reproduction OBSOLETE. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism. go-plus.json reproductive cellular process|cellular process involved in reproduction http://purl.obolibrary.org/obo/GO_0048610 CHEBI:87753 biolink:ChemicalSubstance D-gulonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87753 GO:0048619 biolink:BiologicalProcess embryonic hindgut morphogenesis The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048619 CHEBI:38716 biolink:ChemicalSubstance carboxylic acid dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_38716 PR:000001971 biolink:Protein vascular endothelial growth factor receptor A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. go-plus.json http://purl.obolibrary.org/obo/PR_000001971 GO:0048618 biolink:BiologicalProcess post-embryonic foregut morphogenesis The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048618 GO:0048617 biolink:BiologicalProcess embryonic foregut morphogenesis The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048617 GO:0048616 biolink:BiologicalProcess post-embryonic anterior midgut (ectodermal) morphogenesis The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048616 UBERON:0001560 biolink:AnatomicalEntity neck of organ go-plus.json organ neck http://purl.obolibrary.org/obo/UBERON_0001560 CHEBI:73121 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73121 CHEBI:73124 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73124 GO:0097596 biolink:CellularComponent ventral disc supernumerary microtubule array A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage). go-plus.json supernumerary microtubule array|ventral disk supernumerary microtubule array http://purl.obolibrary.org/obo/GO_0097596 GO:0097595 biolink:CellularComponent ventral disc crossbridge Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet. go-plus.json crossbridge|ventral disk crossbridge http://purl.obolibrary.org/obo/GO_0097595 GO:0097598 biolink:CellularComponent sperm cytoplasmic droplet A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted. go-plus.json sperm residual cytoplasm http://purl.obolibrary.org/obo/GO_0097598 GO:0097597 biolink:CellularComponent ventral disc Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence. go-plus.json ventral adhesive disc|ventral disk|adhesive disc http://purl.obolibrary.org/obo/GO_0097597 GO:0097592 biolink:CellularComponent ventral disc overlap zone A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself). go-plus.json overlap zone|ventral disk overlap zone http://purl.obolibrary.org/obo/GO_0097592 GO:0097591 biolink:CellularComponent ventral disc lateral crest Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet. go-plus.json lateral crest|ventral disk lateral crest http://purl.obolibrary.org/obo/GO_0097591 GO:0097594 biolink:CellularComponent ventral disc dorsal microribbon Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons. go-plus.json ventral disk dorsal microribbon|dorsal ribbon|microribbon|dorsal microribbon http://purl.obolibrary.org/obo/GO_0097594 GO:0009019 biolink:MolecularActivity tRNA (guanine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine. Reactome:R-HSA-6787591|Reactome:R-HSA-6786621|Reactome:R-HSA-6782859 go-plus.json S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity|tRNA guanine 1-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity|transfer ribonucleate guanine 1-methyltransferase activity http://purl.obolibrary.org/obo/GO_0009019 GO:0097593 biolink:CellularComponent ventral disc microtubule array A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane. go-plus.json ventral disk microtubule array|spiral microtubule array|ventral disc spiral microtubule array http://purl.obolibrary.org/obo/GO_0097593 GO:0010007 biolink:CellularComponent magnesium chelatase complex A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner. go-plus.json http://purl.obolibrary.org/obo/GO_0010007 GO:0009018 biolink:MolecularActivity sucrose phosphorylase activity Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate. RHEA:24048|EC:2.4.1.7|MetaCyc:SUCROSE-PHOSPHORYLASE-RXN go-plus.json disaccharide glucosyltransferase activity|sucrose glucosyltransferase activity|sucrose:phosphate alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0009018 GO:0009017 biolink:MolecularActivity succinylglutamate desuccinylase activity Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate. KEGG_REACTION:R00411|EC:3.5.1.96|RHEA:15169|MetaCyc:SUCCGLUDESUCC-RXN go-plus.json AstE|SGDS|N2-succinylglutamate desuccinylase activity|N-succinyl-L-glutamate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0009017 GO:0010006 biolink:CellularComponent Toc complex Protein translocon complex at the chloroplast outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0010006 GO:0009016 biolink:MolecularActivity succinyldiaminopimelate transaminase activity Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate. RHEA:11960|KEGG_REACTION:R04475|MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN|EC:2.6.1.17 go-plus.json succinyldiaminopimelate transferase activity|N-succinyl-L-diaminopimelic glutamic transaminase activity|N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|succinyldiaminopimelate aminotransferase activity http://purl.obolibrary.org/obo/GO_0009016 GO:0010009 biolink:CellularComponent cytoplasmic side of endosome membrane The side (leaflet) of the endosome membrane that faces the cytoplasm. go-plus.json external side of endosome membrane|external leaflet of endosome membrane http://purl.obolibrary.org/obo/GO_0010009 GO:0097590 biolink:BiologicalProcess archaeal-type flagellum-dependent cell motility Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel. go-plus.json archaeal-type flagellar cell motility http://purl.obolibrary.org/obo/GO_0097590 GO:0009015 biolink:MolecularActivity N-succinylarginine dihydrolase activity Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+). EC:3.5.3.23|KEGG_REACTION:R04189|RHEA:19533|MetaCyc:SUCCARGDIHYDRO-RXN go-plus.json N2-succinyl-L-arginine iminohydrolase (decarboxylating)|SADH|arginine succinylhydrolase activity|2-N-succinyl-L-arginine iminohydrolase (decarboxylating)|succinylarginine dihydrolase activity|AstB|AruB|N2-succinylarginine dihydrolase activity http://purl.obolibrary.org/obo/GO_0009015 GO:0010008 biolink:CellularComponent endosome membrane The lipid bilayer surrounding an endosome. NIF_Subcellular:sao978443756 go-plus.json endosomal membrane http://purl.obolibrary.org/obo/GO_0010008 GO:0009014 biolink:MolecularActivity succinyl-diaminopimelate desuccinylase activity Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate. RHEA:22608|EC:3.5.1.18|KEGG_REACTION:R02734|MetaCyc:SUCCDIAMINOPIMDESUCC-RXN go-plus.json N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity http://purl.obolibrary.org/obo/GO_0009014 GO:0009013 biolink:MolecularActivity succinate-semialdehyde dehydrogenase [NAD(P)+] activity Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. MetaCyc:SUCCSEMIALDDEHYDROG-RXN|UM-BBD_reactionID:r0371|EC:1.2.1.16 go-plus.json succinate-semialdehyde:NAD(P)+ oxidoreductase activity|succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) http://purl.obolibrary.org/obo/GO_0009013 GO:0009012 biolink:MolecularActivity aminoglycoside 3''-adenylyltransferase activity Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+). EC:2.7.7.47|MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN|KEGG_REACTION:R02226|RHEA:20245 go-plus.json AAD (3'')|ATP:streptomycin 3''-adenylyltransferase activity|streptomycin 3''-adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0009012 GO:0009011 biolink:MolecularActivity starch synthase activity Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1). MetaCyc:GLYCOGENSYN-RXN|EC:2.4.1.21 go-plus.json ADP-glucose--starch glucosyltransferase activity|ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADPG-starch glucosyltransferase activity|glycogen synthase activity|adenosine diphosphate glucose-starch glucosyltransferase activity|ADPG starch synthetase activity|ADP-glucose starch synthase activity|starch synthetase activity|ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADP-glucose transglucosylase activity|adenosine diphosphoglucose-starch glucosyltransferase activity|starch (bacterial glycogen) synthase activity|ADPglucose-starch glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0009011 GO:0009021 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009021 GO:0009020 biolink:MolecularActivity tRNA (guanosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine. EC:2.1.1.34|Reactome:R-HSA-9024161|RHEA:20077|MetaCyc:2.1.1.34-RXN go-plus.json tRNA (Gm18) 2'-O-methyltransferase activity|tRNA (guanosine 2')-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity|transfer ribonucleate guanosine 2'-methyltransferase activity|tRNA guanosine 2'-methyltransferase activity|S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity|tRNA (Gm18) methyltransferase activity|tRNA guanosine-2'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0009020 GO:0010001 biolink:BiologicalProcess glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. go-plus.json neuroglia differentiation|glia cell differentiation http://purl.obolibrary.org/obo/GO_0010001 GO:0010000 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010000 GO:0010003 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010003 GO:0010002 biolink:BiologicalProcess cardioblast differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json cardioblast cell differentiation|cardiomyocyte generation|cardiac precursor cell differentiation http://purl.obolibrary.org/obo/GO_0010002 GO:0010005 biolink:CellularComponent cortical microtubule, transverse to long axis Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition. go-plus.json http://purl.obolibrary.org/obo/GO_0010005 GO:0010004 biolink:BiologicalProcess gastrulation involving germ band extension A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0010004 GO:0097599 biolink:MolecularActivity xylanase activity Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues. go-plus.json xylosidase activity http://purl.obolibrary.org/obo/GO_0097599 GO:0009029 biolink:MolecularActivity tetraacyldisaccharide 4'-kinase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a). RHEA:20700|KEGG_REACTION:R04657|EC:2.7.1.130|MetaCyc:TETRAACYLDISACC4KIN-RXN go-plus.json lipid-A 4'-kinase activity|ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0009029 GO:0010018 biolink:BiologicalProcess far-red light signaling pathway The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json far red signaling pathway|far red light signalling pathway|far-red light signal transduction http://purl.obolibrary.org/obo/GO_0010018 GO:0009028 biolink:MolecularActivity tartronate-semialdehyde synthase activity Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2). EC:4.1.1.47|MetaCyc:GLYOCARBOLIG-RXN|RHEA:10136|KEGG_REACTION:R00013 go-plus.json glyoxylic carbo-ligase activity|glyoxylate carboligase activity|glyoxylate carbo-ligase activity|glyoxalate carboligase activity|hydroxymalonic semialdehyde carboxylase activity|tartronic semialdehyde carboxylase activity|glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)|tartronate semialdehyde carboxylase activity|glyoxylate carboxy-lyase (dimerizing) http://purl.obolibrary.org/obo/GO_0009028 GO:0010017 biolink:BiologicalProcess red or far-red light signaling pathway The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json red or far-red light signal transduction|phytochrome signaling pathway|red or far red light signaling pathway|red or far-red light signalling pathway|red/far red light signaling pathway http://purl.obolibrary.org/obo/GO_0010017 CHEBI:133867 biolink:ChemicalSubstance 4-O-[di(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133867 chebi_ph7_3 GO:0009027 biolink:MolecularActivity tartrate dehydrogenase activity Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+. RHEA:15209|EC:1.1.1.93|MetaCyc:TARTRATE-DEHYDROGENASE-RXN go-plus.json mesotartrate dehydrogenase activity|tartrate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0009027 GO:0009026 biolink:MolecularActivity tagaturonate reductase activity Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH. EC:1.1.1.58|KEGG_REACTION:R02555|RHEA:17813|MetaCyc:ALTRO-OXIDOREDUCT-RXN go-plus.json altronate oxidoreductase activity|D-tagaturonate reductase activity|altronic oxidoreductase activity|D-altronate:NAD+ 3-oxidoreductase activity|tagaturonate dehydrogenase activity|altronate dehydrogenase activity|TagUAR http://purl.obolibrary.org/obo/GO_0009026 GO:0010019 biolink:BiologicalProcess chloroplast-nucleus signaling pathway The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis. go-plus.json chloroplast-nucleus signalling pathway http://purl.obolibrary.org/obo/GO_0010019 GO:0009025 biolink:MolecularActivity tagatose-bisphosphate aldolase activity Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate. MetaCyc:TAGAALDOL-RXN|RHEA:22948|KEGG_REACTION:R01069|EC:4.1.2.40 go-plus.json AgaZ|AgaY|D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)|tagatose-1,6-bisphosphate aldolase 1|tagatose 1,6-diphosphate aldolase activity|D-tagatose-1,6-bisphosphate triosephosphate lyase activity|KbaY|D-tagatose-1,6-bisphosphate aldolase activity http://purl.obolibrary.org/obo/GO_0009025 GO:0009024 biolink:MolecularActivity tagatose-6-phosphate kinase activity Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate. MetaCyc:TAGAKIN-RXN|RHEA:12420|EC:2.7.1.144 go-plus.json phosphotagatokinase activity|ATP:D-tagatose-6-phosphate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0009024 GO:0009023 biolink:MolecularActivity obsolete tRNA sulfurtransferase OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide. go-plus.json tRNA sulphurtransferase activity|tRNA sulfurtransferase http://purl.obolibrary.org/obo/GO_0009023 GO:0009022 biolink:MolecularActivity tRNA nucleotidyltransferase activity Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. RHEA:10628|EC:2.7.7.56|MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN go-plus.json RNase PH activity|phosphate-dependent exonuclease activity|tRNA:phosphate nucleotidyltransferase activity|ribonuclease PH activity http://purl.obolibrary.org/obo/GO_0009022 GO:0009032 biolink:MolecularActivity thymidine phosphorylase activity Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate. RHEA:16037|EC:2.4.2.4|MetaCyc:THYM-PHOSPH-RXN go-plus.json thymidine-orthophosphate deoxyribosyltransferase activity|thymidine:phosphate deoxy-D-ribosyltransferase activity|pyrimidine phosphorylase activity|thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0009032 CHEBI:133860 biolink:ChemicalSubstance polyunsaturated hydroxylipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133860 chebi_ph7_3 GO:0010010 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010010 GO:0009031 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009031 GO:0009030 biolink:MolecularActivity thiamine-phosphate kinase activity Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate. MetaCyc:THI-P-KIN-RXN|KEGG_REACTION:R00617|RHEA:15913|EC:2.7.4.16 go-plus.json thiamin-phosphate kinase activity|thiamin-monophosphate kinase activity|thiamin monophosphatase activity|thiamine-monophosphate kinase activity|thiamin phosphate kinase activity|ATP:thiamine-phosphate phosphotransferase activity|thiamin monophosphokinase activity http://purl.obolibrary.org/obo/GO_0009030 GO:0010012 biolink:MolecularActivity steroid 22-alpha hydroxylase activity Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0010012 GO:0010011 biolink:MolecularActivity auxin binding Binding to auxin, a plant hormone that regulates aspects of plant growth. go-plus.json auxin receptor http://purl.obolibrary.org/obo/GO_0010011 GO:0010014 biolink:BiologicalProcess meristem initiation Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0010014 GO:0010013 biolink:MolecularActivity N-1-naphthylphthalamic acid binding Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor. go-plus.json http://purl.obolibrary.org/obo/GO_0010013 GO:0010016 biolink:BiologicalProcess shoot system morphogenesis The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground. go-plus.json shoot morphogenesis http://purl.obolibrary.org/obo/GO_0010016 GO:0010015 biolink:BiologicalProcess root morphogenesis The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support. go-plus.json http://purl.obolibrary.org/obo/GO_0010015 GO:0097574 biolink:CellularComponent lateral part of cell The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells. go-plus.json http://purl.obolibrary.org/obo/GO_0097574 GO:0097573 biolink:MolecularActivity glutathione oxidoreductase activity Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione. go-plus.json http://purl.obolibrary.org/obo/GO_0097573 GO:0097576 biolink:BiologicalProcess vacuole fusion Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0097576 GO:0097575 biolink:CellularComponent lateral cell cortex The region directly beneath the plasma membrane of the lateral portion of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097575 GO:0097570 biolink:CellularComponent cyst wall The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0097570 GO:0097572 biolink:CellularComponent right nucleus One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side. go-plus.json http://purl.obolibrary.org/obo/GO_0097572 GO:0097571 biolink:CellularComponent left nucleus One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side. go-plus.json http://purl.obolibrary.org/obo/GO_0097571 CHEBI:24183 biolink:ChemicalSubstance galloyl beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24183 CHEBI:48153 biolink:ChemicalSubstance D-erythrose 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48153 CHEBI:48154 biolink:ChemicalSubstance sulfur oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48154 CHEBI:24190 biolink:ChemicalSubstance gamma-glutamyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24190 GO:0097578 biolink:BiologicalProcess sequestering of copper ion The process of binding or confining copper ions such that they are separated from other components of a biological system. go-plus.json retention of copper ion|storage of copper ion|copper ion sequestering|copper ion retention|sequestration of copper ion|copper ion storage|copper ion sequestration http://purl.obolibrary.org/obo/GO_0097578 GO:0097577 biolink:BiologicalProcess sequestering of iron ion The process of binding or confining iron ions such that they are separated from other components of a biological system. go-plus.json iron ion sequestration|retention of iron ion|iron ion sequestering|storage of iron ion|iron ion retention|sequestration of iron ion|iron ion storage http://purl.obolibrary.org/obo/GO_0097577 GO:0097579 biolink:BiologicalProcess extracellular sequestering of copper ion The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system. go-plus.json extracellular copper ion retention|extracellular retention of copper ion|extracellular copper ion storage|extracellular storage of copper ion|extracellular copper ion sequestering|extracellular copper ion sequestration|extracellular sequestration of copper ion http://purl.obolibrary.org/obo/GO_0097579 GO:0097585 biolink:CellularComponent dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p. go-plus.json Pmt5p-Pmt3p complex http://purl.obolibrary.org/obo/GO_0097585 GO:0097584 biolink:CellularComponent dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p. go-plus.json Pmt5p-Pmt2p complex http://purl.obolibrary.org/obo/GO_0097584 GO:0097587 biolink:CellularComponent MutLgamma complex A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3. go-plus.json http://purl.obolibrary.org/obo/GO_0097587 GO:0097586 biolink:CellularComponent dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p. go-plus.json Pmt4p-Pmt4p complex|dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p dimer|dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p-Pmt4p dimer complex http://purl.obolibrary.org/obo/GO_0097586 GO:0097581 biolink:BiologicalProcess lamellipodium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0097581 GO:0097580 biolink:BiologicalProcess intracellular sequestering of copper ion The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system. go-plus.json intracellular copper ion storage|intracellular retention of copper ion|intracellular storage of copper ion|intracellular copper ion sequestration|intracellular copper ion sequestering|intracellular sequestration of copper ion|intracellular copper ion retention http://purl.obolibrary.org/obo/GO_0097580 GO:0097583 biolink:CellularComponent dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p. go-plus.json Pmt1p-Pmt3p complex http://purl.obolibrary.org/obo/GO_0097583 GO:0009009 biolink:MolecularActivity site-specific recombinase activity Catalysis of the formation of new phosphodiester bonds between a pair of short, unique target DNA sequences. go-plus.json RecA-family recombinase activity http://purl.obolibrary.org/obo/GO_0009009 goslim_pir GO:0097582 biolink:CellularComponent dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p. go-plus.json Pmt1p-Pmt2p complex http://purl.obolibrary.org/obo/GO_0097582 GO:0009008 biolink:MolecularActivity DNA-methyltransferase activity Catalysis of the transfer of a methyl group to a DNA molecule. Reactome:R-HSA-5227490 go-plus.json DNA methylase|deoxyribonucleic acid modification methylase activity|DNA transmethylase activity|deoxyribonucleic acid methylase activity|deoxyribonucleate methyltransferase activity|DNA methyltransferase activity|deoxyribonucleate methylase activity|Type II DNA methylase|deoxyribonucleic acid methyltransferase activity http://purl.obolibrary.org/obo/GO_0009008 GO:0009007 biolink:MolecularActivity site-specific DNA-methyltransferase (adenine-specific) activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine. MetaCyc:2.1.1.72-RXN|EC:2.1.1.72|RHEA:15197 go-plus.json modification methylase activity|restriction-modification system activity|DNA adenine methylase|N-6 adenine-specific DNA methylase activity|EcoRI methylase http://purl.obolibrary.org/obo/GO_0009007 CHEBI:24195 biolink:ChemicalSubstance gamma-glutamylcysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24195 GO:0009006 biolink:MolecularActivity obsolete siroheme synthase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json siroheme synthase activity|sirohaem synthase activity http://purl.obolibrary.org/obo/GO_0009006 GO:0009005 biolink:MolecularActivity obsolete signal peptidase II activity OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group. go-plus.json lipoprotein signal peptidase activity|signal peptidase II activity|premurein-leader peptidase activity|premurein leader proteinase activity|SPase II activity|prolipoprotein signal peptidase activity|leader peptidase II|prolipoprotein-signal peptidase activity http://purl.obolibrary.org/obo/GO_0009005 GO:0009004 biolink:MolecularActivity obsolete signal peptidase I activity OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor. go-plus.json HOSP|signalase activity|signal peptidase I activity|bacterial leader peptidase 1|bacterial leader peptidase I activity|signal peptide hydrolase activity|leader peptide hydrolase activity|eukaryotic signal proteinase|propeptidase activity|prokaryotic signal proteinase|pilin leader peptidase|PuIO prepilin peptidase|leader peptidase I|SPase I activity|Escherichia coli leader peptidase|phage-procoat-leader peptidase activity|prokaryotic leader peptidase|prokaryotic signal peptidase|leader proteinase activity|leader peptidase activity|signal proteinase activity|SPC|eukaryotic signal peptidase http://purl.obolibrary.org/obo/GO_0009004 GO:0009003 biolink:MolecularActivity obsolete signal peptidase activity OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor. go-plus.json signal peptidase activity http://purl.obolibrary.org/obo/GO_0009003 CHEBI:48144 biolink:ChemicalSubstance cyclosiloxane go-plus.json http://purl.obolibrary.org/obo/CHEBI_48144 GO:0009002 biolink:MolecularActivity serine-type D-Ala-D-Ala carboxypeptidase activity Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine. EC:3.4.16.4|MetaCyc:3.4.16.4-RXN go-plus.json DD-transpeptidase activity|D-alanyl-D-alanine-carboxypeptidase activity|D-alanyl carboxypeptidase activity|D-alanyl-D-alanine-cleaving-peptidase activity|DD-carboxypeptidase|DD-peptidase activity|D-alanyl-D-alanine-cleaving peptidase activity|D-alanine carboxypeptidase|D-alanyl-D-alanine carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0009002 GO:0009001 biolink:MolecularActivity serine O-acetyltransferase activity Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA. MetaCyc:SERINE-O-ACETTRAN-RXN|KEGG_REACTION:R00586|EC:2.3.1.30|RHEA:24560 go-plus.json acetyl-CoA:L-serine O-acetyltransferase activity|serine acetyltransferase activity|L-serine acetyltransferase activity|serine transacetylase activity|SATase activity http://purl.obolibrary.org/obo/GO_0009001 CHEBI:48145 biolink:ChemicalSubstance cyclotetrasiloxane go-plus.json http://purl.obolibrary.org/obo/CHEBI_48145 chebi_ph7_3 GO:0009000 biolink:MolecularActivity selenocysteine lyase activity Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor. EC:4.4.1.16|RHEA:11632|MetaCyc:SELENOCYSTEINE-LYASE-RXN|Reactome:R-HSA-2408524 go-plus.json L-selenocysteine selenide-lyase (L-alanine-forming)|selenocysteine reductase activity|selenocysteine beta-lyase activity http://purl.obolibrary.org/obo/GO_0009000 GO:0009010 biolink:MolecularActivity sorbitol-6-phosphate 2-dehydrogenase activity Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+. EC:1.1.1.140|RHEA:19837|MetaCyc:SORB6PDEHYDROG-RXN go-plus.json D-sorbitol 6-phosphate dehydrogenase activity|sorbitol-6-P-dehydrogenase activity|glucitol-6-phosphate dehydrogenase activity|D-sorbitol-6-phosphate dehydrogenase activity|D-glucitol-6-phosphate dehydrogenase activity|D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity|ketosephosphate reductase activity http://purl.obolibrary.org/obo/GO_0009010 GO:0097589 biolink:CellularComponent archaeal-type flagellum A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function. go-plus.json archaellum|archaeal flagellum|archaella http://purl.obolibrary.org/obo/GO_0097589 GO:0097588 biolink:BiologicalProcess archaeal or bacterial-type flagellum-dependent cell motility Cell motility due to movement of bacterial- or archaeal-type flagella. go-plus.json http://purl.obolibrary.org/obo/GO_0097588 CHEBI:48136 biolink:ChemicalSubstance xanthosines go-plus.json http://purl.obolibrary.org/obo/CHEBI_48136 CHEBI:24168 biolink:ChemicalSubstance galactosylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24168 UBERON:0001508 biolink:AnatomicalEntity arch of aorta the convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery go-plus.json aortic arch|arcus aortae|thoracic aorta http://purl.obolibrary.org/obo/UBERON_0001508 CHEBI:24167 biolink:ChemicalSubstance galactosylglycerol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24167 CHEBI:133812 biolink:ChemicalSubstance 5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133812 chebi_ph7_3 CHEBI:48131 biolink:ChemicalSubstance nonanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48131 CHEBI:24160 biolink:ChemicalSubstance galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24160 CHEBI:48132 biolink:ChemicalSubstance tetracenomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48132 CHEBI:24164 biolink:ChemicalSubstance galactosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24164 CHEBI:133819 biolink:ChemicalSubstance 13-HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133819 chebi_ph7_3 CHEBI:24163 biolink:ChemicalSubstance galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_24163 UBERON:0001510 biolink:AnatomicalEntity skin of knee A zone of skin that is part of a knee [Automatically generated definition]. go-plus.json knee zone of skin|zone of skin of knee|knee skin http://purl.obolibrary.org/obo/UBERON_0001510 UBERON:0001512 biolink:AnatomicalEntity skin of ankle A zone of skin that is part of an ankle [Automatically generated definition]. go-plus.json ankle skin|tarsal region skin|zone of skin of ankle|ankle zone of skin http://purl.obolibrary.org/obo/UBERON_0001512 UBERON:0001511 biolink:AnatomicalEntity skin of leg A zone of skin that is part of a leg [Automatically generated definition]. go-plus.json zone of skin of leg|leg skin|leg zone of skin http://purl.obolibrary.org/obo/UBERON_0001511 PR:000001902 biolink:Protein nuclear receptor ROR-gamma A protein that is a translation product of the human RORC gene or a 1:1 ortholog thereof. go-plus.json RORG|nuclear receptor subfamily 1 group F member 3|thymus orphan receptor|nuclear receptor RZR-gamma|RZRG|TOR|NR1F3|Thor|retinoid-related orphan receptor-gamma|RORC http://purl.obolibrary.org/obo/PR_000001902 CHEBI:48125 biolink:ChemicalSubstance trihydrogensilicate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48125 CHEBI:48129 biolink:ChemicalSubstance benzoisochromanequinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_48129 CHEBI:48120 biolink:ChemicalSubstance anthracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48120 CHEBI:48122 biolink:ChemicalSubstance hydrogensilicate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48122 CHEBI:48121 biolink:ChemicalSubstance polyene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48121 CHEBI:48124 biolink:ChemicalSubstance dihydrogensilicate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48124 CHEBI:24175 biolink:ChemicalSubstance galacturonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24175 CHEBI:24174 biolink:ChemicalSubstance galacturonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_24174 CHEBI:48123 biolink:ChemicalSubstance silicate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_48123 CHEBI:63701 biolink:ChemicalSubstance (-)-alpha-cuprenene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63701 chebi_ph7_3 CHEBI:133820 biolink:ChemicalSubstance 9-HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133820 chebi_ph7_3 CHEBI:63704 biolink:ChemicalSubstance (+)-Tau-muurolol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63704 chebi_ph7_3 CHEBI:63703 biolink:ChemicalSubstance (-)-delta-cadinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63703 chebi_ph7_3 CHEBI:63702 biolink:ChemicalSubstance avermitilol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63702 chebi_ph7_3 CHEBI:63709 biolink:ChemicalSubstance bicyclogermacrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63709 chebi_ph7_3 CHEBI:63708 biolink:ChemicalSubstance isopimara-8(14),15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63708 chebi_ph7_3 CHEBI:63707 biolink:ChemicalSubstance syn-labda-8(17),12E,14-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63707 chebi_ph7_3 UBERON:0001500 biolink:AnatomicalEntity muscle of manus Any muscle organ that is part of a manus [Automatically generated definition]. go-plus.json manus muscle organ|muscle of hand|hand muscle|manus muscle|muscle organ of manus http://purl.obolibrary.org/obo/UBERON_0001500 CHEBI:24148 biolink:ChemicalSubstance galactonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24148 CHEBI:48117 biolink:ChemicalSubstance 1-glycosylimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_48117 CHEBI:48116 biolink:ChemicalSubstance nucleotide-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48116 CHEBI:24145 biolink:ChemicalSubstance galactoglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24145 CHEBI:24149 biolink:ChemicalSubstance galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24149 CHEBI:24144 biolink:ChemicalSubstance galactoglucomannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_24144 CHEBI:48110 biolink:ChemicalSubstance trinitrobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48110 CHEBI:48113 biolink:ChemicalSubstance 1,3,5-trinitrobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48113 chebi_ph7_3 CHEBI:63712 biolink:ChemicalSubstance baruol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63712 chebi_ph7_3 CHEBI:63711 biolink:ChemicalSubstance sesquithujene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63711 chebi_ph7_3 CHEBI:63710 biolink:ChemicalSubstance 7-epi-sesquithujene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63710 chebi_ph7_3 CHEBI:63715 biolink:ChemicalSubstance 8-oxo-dGDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63715 chebi_ph7_3 NCBITaxon:71193 biolink:OrganismalEntity Elateroidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_71193 CHEBI:63714 biolink:ChemicalSubstance 7-methylguanosine 5'-diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63714 chebi_ph7_3 CHEBI:38785 biolink:ChemicalSubstance morpholines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38785 CHEBI:38784 biolink:ChemicalSubstance oxetanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38784 CHEBI:24158 biolink:ChemicalSubstance galactosaminoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_24158 CHEBI:24156 biolink:ChemicalSubstance galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24156 CHEBI:48107 biolink:ChemicalSubstance nitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48107 CHEBI:48109 biolink:ChemicalSubstance nitrobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_48109 CHEBI:24151 biolink:ChemicalSubstance galactooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24151 CHEBI:24150 biolink:ChemicalSubstance galactonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24150 CHEBI:24155 biolink:ChemicalSubstance galactosamine sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24155 CHEBI:24154 biolink:ChemicalSubstance galactosamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24154 CHEBI:38797 biolink:ChemicalSubstance dihydropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38797 CHEBI:63727 biolink:ChemicalSubstance cis-4-hydroxy-L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63727 chebi_ph7_3 CHEBI:63726 biolink:ChemicalSubstance neuroprotective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_63726 CHEBI:63729 biolink:ChemicalSubstance 7-methylguanosine 5'-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63729 CHEBI:63728 biolink:ChemicalSubstance 8-oxo-dGDP go-plus.json http://purl.obolibrary.org/obo/CHEBI_63728 CHEBI:38796 biolink:ChemicalSubstance pteroates go-plus.json http://purl.obolibrary.org/obo/CHEBI_38796 CHEBI:38795 biolink:ChemicalSubstance pteroic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_38795 CHEBI:38794 biolink:ChemicalSubstance pteroic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38794 CHEBI:38793 biolink:ChemicalSubstance pteroate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38793 GO:0048585 biolink:BiologicalProcess negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. go-plus.json downregulation of response to stimulus|down regulation of response to stimulus|inhibition of response to stimulus|down-regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048585 gocheck_do_not_manually_annotate GO:0048584 biolink:BiologicalProcess positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. go-plus.json upregulation of response to stimulus|stimulation of response to stimulus|up-regulation of response to stimulus|activation of response to stimulus|up regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048584 gocheck_do_not_manually_annotate GO:0048583 biolink:BiologicalProcess regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0048583 gocheck_do_not_manually_annotate GO:0097510 biolink:BiologicalProcess base-excision repair, AP site formation via deaminated base removal A base-excision repair, AP site formation process occurring via excision of a deaminated base. go-plus.json http://purl.obolibrary.org/obo/GO_0097510 GO:0048582 biolink:BiologicalProcess positive regulation of post-embryonic development Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. go-plus.json upregulation of post-embryonic development|stimulation of post-embryonic development|up-regulation of post-embryonic development|activation of post-embryonic development|up regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0048582 GO:0048581 biolink:BiologicalProcess negative regulation of post-embryonic development Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. go-plus.json down-regulation of post-embryonic development|downregulation of post-embryonic development|down regulation of post-embryonic development|inhibition of post-embryonic development http://purl.obolibrary.org/obo/GO_0048581 GO:0048580 biolink:BiologicalProcess regulation of post-embryonic development Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048580 GO:1903989 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903989 GO:1903988 biolink:BiologicalProcess iron ion export across plasma membrane The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json iron cation export|ferrous iron export|iron(2+) export|ferrous iron export across plasma membrane http://purl.obolibrary.org/obo/GO_1903988 GO:1903985 biolink:BiologicalProcess regulation of intestinal D-glucose absorption Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption. go-plus.json http://purl.obolibrary.org/obo/GO_1903985 GO:1903984 biolink:BiologicalProcess positive regulation of TRAIL-activated apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway. go-plus.json up-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up-regulation of TRAIL-induced apoptotic signaling pathway|up-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|upregulation of TRAIL-activated apoptotic signaling pathway|upregulation of TRAIL-induced apoptotic signaling pathway|upregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|upregulation of TRAIL-activated extrinsic apoptotic signaling pathway|up regulation of TRAIL-activated apoptotic signaling pathway|activation of TRAIL-activated apoptotic signaling pathway|up regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up regulation of TRAIL-induced apoptotic signaling pathway|positive regulation of TRAIL-induced apoptotic signaling pathway|activation of TRAIL-induced apoptotic signaling pathway|positive regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|activation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up regulation of TRAIL-activated extrinsic apoptotic signaling pathway|positive regulation of TRAIL-activated extrinsic apoptotic signaling pathway|activation of TRAIL-activated extrinsic apoptotic signaling pathway|up-regulation of TRAIL-activated apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1903984 GO:0048589 biolink:BiologicalProcess developmental growth The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. go-plus.json http://purl.obolibrary.org/obo/GO_0048589 GO:0048588 biolink:BiologicalProcess developmental cell growth The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. go-plus.json developmental growth of a unicellular organism http://purl.obolibrary.org/obo/GO_0048588 GO:1903983 biolink:BiologicalProcess positive regulation of microvillus length A process that increases the length of a microvillus. go-plus.json up regulation of regulation of microvillus length|upregulation of regulation of microvillus length|activation of regulation of microvillus length|up-regulation of regulation of microvillus length http://purl.obolibrary.org/obo/GO_1903983 GO:0048587 biolink:BiologicalProcess regulation of short-day photoperiodism, flowering Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048587 GO:1903982 biolink:BiologicalProcess negative regulation of microvillus length A process that decreases the length of a microvillus. go-plus.json down-regulation of regulation of microvillus length|downregulation of regulation of microvillus length|down regulation of regulation of microvillus length|inhibition of regulation of microvillus length http://purl.obolibrary.org/obo/GO_1903982 GO:1903981 biolink:MolecularActivity enterobactin binding Binding to enterobactin. go-plus.json siderophore binding|enterochelin binding http://purl.obolibrary.org/obo/GO_1903981 GO:0048586 biolink:BiologicalProcess regulation of long-day photoperiodism, flowering Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048586 GO:1903991 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903991 GO:1903990 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903990 CHEBI:73092 biolink:ChemicalSubstance 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73092 GO:0097519 biolink:CellularComponent DNA recombinase complex A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0097519 CHEBI:73091 biolink:ChemicalSubstance 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73091 GO:0097516 biolink:CellularComponent microvillar actin bundle A parallel bundle of actin filaments at the core of a microvillus. go-plus.json http://purl.obolibrary.org/obo/GO_0097516 GO:0097515 biolink:CellularComponent asexual spore wall A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species. go-plus.json http://purl.obolibrary.org/obo/GO_0097515 SO:0000714 biolink:SequenceFeature nucleotide_motif A region of nucleotide sequence corresponding to a known motif. go-plus.json nucleotide motif|INSDC_note:nucleotide_motif|INSDC_feature:misc_feature http://purl.obolibrary.org/obo/SO_0000714 SOFA GO:0097518 biolink:CellularComponent parallel actin filament bundle An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity. go-plus.json http://purl.obolibrary.org/obo/GO_0097518 GO:0097517 biolink:CellularComponent contractile actin filament bundle An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle. go-plus.json http://purl.obolibrary.org/obo/GO_0097517 SO:0000713 biolink:SequenceFeature DNA_motif A motif that is active in the DNA form of the sequence. http://en.wikipedia.org/wiki/DNA_motif go-plus.json DNA motif http://purl.obolibrary.org/obo/SO_0000713 GO:0097512 biolink:CellularComponent cardiac myofibril A cardiac myofibril is a myofibril specific to cardiac muscle cells. go-plus.json http://purl.obolibrary.org/obo/GO_0097512 GO:0097511 biolink:CellularComponent dendritic cell dendrite A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. go-plus.json http://purl.obolibrary.org/obo/GO_0097511 GO:0097514 biolink:CellularComponent sexual spore wall A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0097514 PO:0025499 biolink:OntologyClass sepal epidermis giant cell An epidermal pavement cell (PO:0000332) that is part of sepal epidermis (PO:0006040) and is approximately one fifth the length of a sepal. go-plus.json がく片表皮巨大細胞 (Japanese, exact)|giant cell (broad) http://purl.obolibrary.org/obo/PO_0025499 GO:0097513 biolink:CellularComponent myosin II filament A bipolar filament composed of myosin II molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0097513 PO:0025498 biolink:OntologyClass cardinal part of multi-tissue plant structure A plant structure (PO:0009011) that is a proper part of a multi-tissue plant structure (PO:0025496) and includes portions of plant tissues (PO:0009007) of at least two different types. go-plus.json 複数の組織からなる植物構造の基本（主要）部分 (Japanese, exact)|parte cardinal de estructura vegetal con múltiples tejidos (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025498 GO:0048596 biolink:BiologicalProcess embryonic camera-type eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryonic development. go-plus.json embryonic eye morphogenesis http://purl.obolibrary.org/obo/GO_0048596 PO:0025497 biolink:OntologyClass collective plant structure A plant structure (PO:0009011) that is a proper part of a whole plant (PO:0000003) and includes two or more adjacent plant organs (PO:0009008) or adjacent cardinal organ parts (PO:0025001), along with any associated portions of plant tissue (PO:0009007). go-plus.json estructura vegetal colectiva (Spanish, exact)|集合的植物構造 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025497 GO:0048595 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048595 PO:0025496 biolink:OntologyClass multi-tissue plant structure A plant structure (PO:0009011) that has as parts two or more portions of plant tissue (PO:0009007) of at least two different types and which through specific morphogenetic processes forms a single structural unit demarcated by primarily bona-fide boundaries from other structural units of different types. go-plus.json estructura vegetal con múltiples tejidos (Spanish, exact)|複数の組織からなる植物構造 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025496 GO:0048594 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048594 GO:0097521 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097521 GO:0097520 biolink:CellularComponent nucleotide-excision repair, preincision complex A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. go-plus.json UvrA(2)B(2) complex|UvrA(2)-UvrB(2) complex|UvrB dimer http://purl.obolibrary.org/obo/GO_0097520 GO:0048593 biolink:BiologicalProcess camera-type eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. go-plus.json camera-style eye morphogenesis http://purl.obolibrary.org/obo/GO_0048593 GO:0048592 biolink:BiologicalProcess eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048592 GO:0048591 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048591 GO:0048590 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048590 PO:0025490 biolink:OntologyClass plant ovary ovule A plant ovule (PO:0020006) that is part of a plant ovary (PO:0009072). go-plus.json óvulo del ovario (Spanish, exact)|子房胚珠 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025490 GO:1903999 biolink:BiologicalProcess negative regulation of eating behavior Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior. go-plus.json down regulation of eating behavior|inhibition of eating behaviour|downregulation of eating behavior|down-regulation of eating behavior|down-regulation of eating behaviour|negative regulation of eating behaviour|inhibition of eating behavior|downregulation of eating behaviour|down regulation of eating behaviour http://purl.obolibrary.org/obo/GO_1903999 GO:1903998 biolink:BiologicalProcess regulation of eating behavior Any process that modulates the frequency, rate or extent of eating behavior. go-plus.json regulation of eating behaviour http://purl.obolibrary.org/obo/GO_1903998 GO:1903997 biolink:BiologicalProcess positive regulation of non-membrane spanning protein tyrosine kinase activity Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity. go-plus.json activation of janus kinase 1 activity|up regulation of p60c-src protein tyrosine kinase activity|activation of janus kinase 2 activity|activation of janus kinase 3 activity|activation of cytoplasmic protein tyrosine kinase activity|positive regulation of p60c-src protein tyrosine kinase activity|up-regulation of non-membrane spanning protein tyrosine kinase activity|activation of non-membrane spanning protein tyrosine kinase activity|up-regulation of janus kinase 1 activity|up-regulation of janus kinase 2 activity|positive regulation of cytoplasmic protein tyrosine kinase activity|upregulation of focal adhesion kinase activity|up regulation of Bruton's tyrosine kinase activity|up-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up-regulation of janus kinase 3 activity|activation of p60c-src protein tyrosine kinase activity|up-regulation of non-specific protein-tyrosine kinase activity|up regulation of cytoplasmic protein tyrosine kinase activity|positive regulation of Bruton's tyrosine kinase activity|up-regulation of p60c-src protein tyrosine kinase activity|activation of Bruton's tyrosine kinase activity|upregulation of janus kinase 1 activity|upregulation of janus kinase 2 activity|up-regulation of focal adhesion kinase activity|upregulation of janus kinase 3 activity|upregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of non-membrane spanning protein tyrosine kinase activity|upregulation of non-specific protein-tyrosine kinase activity|upregulation of cytoplasmic protein tyrosine kinase activity|up-regulation of Bruton's tyrosine kinase activity|activation of focal adhesion kinase activity|upregulation of p60c-src protein tyrosine kinase activity|up regulation of janus kinase 1 activity|up regulation of janus kinase 2 activity|up regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|positive regulation of janus kinase 1 activity|up regulation of janus kinase 3 activity|positive regulation of focal adhesion kinase activity|upregulation of non-membrane spanning protein tyrosine kinase activity|activation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of non-specific protein-tyrosine kinase activity|positive regulation of janus kinase 2 activity|up-regulation of cytoplasmic protein tyrosine kinase activity|positive regulation of janus kinase 3 activity|positive regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of focal adhesion kinase activity|activation of non-specific protein-tyrosine kinase activity|positive regulation of non-specific protein-tyrosine kinase activity|upregulation of Bruton's tyrosine kinase activity http://purl.obolibrary.org/obo/GO_1903997 GO:1903996 biolink:BiologicalProcess negative regulation of non-membrane spanning protein tyrosine kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity. go-plus.json negative regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|downregulation of focal adhesion kinase activity|negative regulation of janus kinase 2 activity|down-regulation of janus kinase 2 activity|negative regulation of non-specific protein-tyrosine kinase activity|negative regulation of janus kinase 3 activity|down-regulation of janus kinase 3 activity|down-regulation of non-specific protein-tyrosine kinase activity|down regulation of Bruton's tyrosine kinase activity|negative regulation of cytoplasmic protein tyrosine kinase activity|down-regulation of cytoplasmic protein tyrosine kinase activity|down regulation of focal adhesion kinase activity|downregulation of Bruton's tyrosine kinase activity|negative regulation of p60c-src protein tyrosine kinase activity|inhibition of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down-regulation of p60c-src protein tyrosine kinase activity|inhibition of non-specific protein-tyrosine kinase activity|inhibition of focal adhesion kinase activity|down-regulation of non-membrane spanning protein tyrosine kinase activity|inhibition of janus kinase 1 activity|inhibition of janus kinase 2 activity|downregulation of cytoplasmic protein tyrosine kinase activity|inhibition of janus kinase 3 activity|negative regulation of Bruton's tyrosine kinase activity|down-regulation of Bruton's tyrosine kinase activity|down regulation of cytoplasmic protein tyrosine kinase activity|down regulation of janus kinase 1 activity|inhibition of p60c-src protein tyrosine kinase activity|down regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down regulation of janus kinase 2 activity|down regulation of janus kinase 3 activity|down regulation of non-specific protein-tyrosine kinase activity|downregulation of non-membrane spanning protein tyrosine kinase activity|downregulation of janus kinase 1 activity|downregulation of janus kinase 2 activity|negative regulation of focal adhesion kinase activity|downregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down-regulation of focal adhesion kinase activity|inhibition of cytoplasmic protein tyrosine kinase activity|down regulation of non-membrane spanning protein tyrosine kinase activity|downregulation of janus kinase 3 activity|downregulation of non-specific protein-tyrosine kinase activity|down regulation of p60c-src protein tyrosine kinase activity|inhibition of Bruton's tyrosine kinase activity|inhibition of non-membrane spanning protein tyrosine kinase activity|downregulation of p60c-src protein tyrosine kinase activity|down-regulation of janus kinase 1 activity|negative regulation of janus kinase 1 activity http://purl.obolibrary.org/obo/GO_1903996 GO:1903995 biolink:BiologicalProcess regulation of non-membrane spanning protein tyrosine kinase activity Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity. go-plus.json regulation of focal adhesion kinase activity|regulation of Bruton's tyrosine kinase activity|regulation of cytoplasmic protein tyrosine kinase activity|regulation of janus kinase 1 activity|regulation of janus kinase 2 activity|regulation of ATP:protein-tyrosine O-phosphotransferase activity|regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|regulation of janus kinase 3 activity|regulation of non-specific protein-tyrosine kinase activity|regulation of p60c-src protein tyrosine kinase activity http://purl.obolibrary.org/obo/GO_1903995 GO:1903994 biolink:BiologicalProcess obsolete positive regulation of protein stabilization OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein stabilization. go-plus.json up regulation of protein sequestering|up-regulation of lysosomal protein stabilization|upregulation of protein stabilization|up-regulation of protein stabilization activity|positive regulation of positive regulation of protein stability|upregulation of lysosomal protein stabilization|upregulation of protein sequestering|up regulation of protein stabilization|up regulation of positive regulation of protein stability|activation of protein stabilization|activation of protein stabilization activity|up-regulation of protein sequestering|up regulation of lysosomal protein stabilization|positive regulation of protein stabilization activity|upregulation of positive regulation of protein stability|positive regulation of lysosomal protein stabilization|up regulation of protein stabilization activity|up-regulation of protein stabilization|activation of protein sequestering|activation of lysosomal protein stabilization|positive regulation of protein stabilization|positive regulation of protein sequestering|up-regulation of positive regulation of protein stability|upregulation of protein stabilization activity|activation of positive regulation of protein stability http://purl.obolibrary.org/obo/GO_1903994 GO:0048599 biolink:BiologicalProcess oocyte development The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048599 GO:1903993 biolink:BiologicalProcess obsolete negative regulation of protein stabilization OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein stabilization. go-plus.json negative regulation of protein stabilization|inhibition of protein stabilization activity|downregulation of protein sequestering|down regulation of protein stabilization|inhibition of lysosomal protein stabilization|down-regulation of positive regulation of protein stability|negative regulation of positive regulation of protein stability|down regulation of protein sequestering|downregulation of protein stabilization|down regulation of lysosomal protein stabilization|downregulation of positive regulation of protein stability|inhibition of protein sequestering|negative regulation of protein stabilization activity|down-regulation of protein stabilization activity|downregulation of lysosomal protein stabilization|down-regulation of protein stabilization|down regulation of positive regulation of protein stability|inhibition of positive regulation of protein stability|inhibition of protein stabilization|negative regulation of lysosomal protein stabilization|down-regulation of lysosomal protein stabilization|downregulation of protein stabilization activity|down-regulation of protein sequestering|negative regulation of protein sequestering|down regulation of protein stabilization activity http://purl.obolibrary.org/obo/GO_1903993 GO:0048598 biolink:BiologicalProcess embryonic morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. go-plus.json embryonic anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0048598 GO:1903992 biolink:BiologicalProcess obsolete regulation of protein stabilization OBSOLETE. Any process that modulates the frequency, rate or extent of protein stabilization. go-plus.json regulation of protein sequestering|regulation of lysosomal protein stabilization|regulation of positive regulation of protein stability|regulation of protein stabilization|regulation of protein stabilization activity http://purl.obolibrary.org/obo/GO_1903992 GO:0048597 biolink:BiologicalProcess post-embryonic camera-type eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during post-embryonic development. go-plus.json post-embryonic eye morphogenesis|post-embryonic camera-style eye morphogenesis http://purl.obolibrary.org/obo/GO_0048597 SO:0000704 biolink:SequenceFeature gene A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions. http://en.wikipedia.org/wiki/Gene go-plus.json INSDC_feature:gene http://purl.obolibrary.org/obo/SO_0000704 SOFA GO:0097527 biolink:BiologicalProcess necroptotic signaling pathway A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered. go-plus.json necroptosis signaling pathway|necroptotic signal transduction|necroptotic signalling pathway|necroptosis signaling http://purl.obolibrary.org/obo/GO_0097527 GO:0097526 biolink:CellularComponent spliceosomal tri-snRNP complex A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP. go-plus.json http://purl.obolibrary.org/obo/GO_0097526 GO:0097529 biolink:BiologicalProcess myeloid leukocyte migration The movement of a myeloid leukocyte within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0097529 GO:0097528 biolink:BiologicalProcess execution phase of necroptosis A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died. go-plus.json necroptotic execution phase|execution phase of necroptotic process|necroptosis http://purl.obolibrary.org/obo/GO_0097528 GO:0097523 biolink:CellularComponent transcription ternary complex A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript. go-plus.json transcription protein-DNA-RNA complex http://purl.obolibrary.org/obo/GO_0097523 GO:0097522 biolink:CellularComponent protein-DNA ISRE complex A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0097522 GO:0097525 biolink:CellularComponent spliceosomal snRNP complex A small ribonucleoprotein complex involved in formation of the spliceosome. go-plus.json http://purl.obolibrary.org/obo/GO_0097525 GO:0097524 biolink:CellularComponent sperm plasma membrane A plasma membrane that is part of a sperm cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097524 PO:0025487 biolink:OntologyClass bract primordium A phyllome primordium (PO:0025487) that is committed to the development of a flower bract (PO:0009055). go-plus.json portion of bract primordium tissue (exact)|primordio de la bráctea (Spanish, exact)|苞原基（可視的） (Japanese, exact)|bract primordia (exact, plural) http://purl.obolibrary.org/obo/PO_0025487 PO:0025486 biolink:OntologyClass stamen anlagen A phyllome anlagen (PO:0025430) that will give rise to a stamen primordium (PO:0004705) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). go-plus.json anlagen del estambre (Spanish, exact)|雄蕊原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025486 PO:0025485 biolink:OntologyClass sepal anlagen A phyllome anlagen (PO:0025430) that will give rise to a sepal primordium (PO:0004704) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). go-plus.json がく片原基 (Japanese, exact)|anlagen del sépalo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025485 PO:0025484 biolink:OntologyClass petal anlagen A phyllome anlagen (PO:0025430) that will give rise to a petal primordium (PO:0000021) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). go-plus.json 花弁原基 (Japanese, exact)|anlagen del pétalo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025484 PO:0025482 biolink:OntologyClass bract anlagen A phyllome anlagen (PO:0025430) that will give rise to a bract primordium (PO:0025487) and is part of a peripheral zone (PO:000225) of a reproductive shoot apical meristem (PO:0008028). go-plus.json anlagen de bráctea (Spanish, exact)|苞原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025482 PO:0025480 biolink:OntologyClass shoot-borne root primordium A root primordium (PO:0005029) that is committed to the development of a shoot-borne root (PO:0000042). go-plus.json primordio del eje del epiblasto de la raíz (Spanish, exact)|portion of shoot-borne root primordium tissue (exact)|adventitious root primordium (broad)|シュート細胞由来の根原基（可視的） (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025480 PO:0025478 biolink:OntologyClass androecium primordium A floral structure primordium (PO:0025477) that is committed to the development of an androecium (PO:0009061). go-plus.json 雄蕊群原基(可視的） (Japanese, exact)|portion of androecium primordium tissue (exact)|primordium del androecio (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025478 PO:0025477 biolink:OntologyClass floral organ primordium A primordium (PO:0025127) that is committed to the development of a floral organ (PO:0025395) and is part of a reproductive shoot apex (PO:0025222). go-plus.json primordio de organo floral (Spanish, exact)|floral structure primordia (exact, plural)|花器官原基 (Japanese, exact)|portion of floral structure primordium tissue (exact) http://purl.obolibrary.org/obo/PO_0025477 CL:0001200 biolink:Cell lymphocyte of B lineage, CD19-positive A lymphocyte of B lineage that is CD19-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0001200 CL:0001202 biolink:Cell CD86-positive plasmablast A plasmablast that is CD86-positive. go-plus.json CD86-positive, CD20-negative plasmablast|CD86+ plasmablast http://purl.obolibrary.org/obo/CL_0001202 SO:0000727 biolink:SequenceFeature cis_regulatory_module A regulatory region where transcription factor binding sites are clustered to regulate various aspects of transcription activities. (CRMs can be located a few kb to hundreds of kb upstream of the core promoter, in the coding sequence, within introns, or in the untranslated regions (UTR) sequences, and even on a different chromosome). A single gene can be regulated by multiple CRMs to give precise control of its spatial and temporal expression. CRMs function as nodes in large, intertwined regulatory network. CRM DNA accessibility is subject to regulation by dbTFs and transcription co-TFs. go-plus.json TF module|transcription factor module|cis regulatory module|CRM http://purl.obolibrary.org/obo/SO_0000727 SOFA GO:0097509 biolink:MolecularActivity oxanine DNA N-glycosylase activity DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination. go-plus.json oxanine-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0097509 GO:0097508 biolink:MolecularActivity xanthine DNA N-glycosylase activity DNA N-glycosylase activity acting on deaminated guanine (xanthine). go-plus.json xanthine-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0097508 CL:0001201 biolink:Cell B cell, CD19-positive A B cell that is CD19-positive. go-plus.json B lymphocyte, CD19-positive|CD19-positive B cell|B-lymphocyte, CD19-positive|CD19+ B cell|B-cell, CD19-positive http://purl.obolibrary.org/obo/CL_0001201 GO:0097505 biolink:CellularComponent Rad6-Rad18 complex A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0097505 GO:0097504 biolink:CellularComponent Gemini of coiled bodies Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA). go-plus.json Gems http://purl.obolibrary.org/obo/GO_0097504 GO:0097507 biolink:MolecularActivity hypoxanthine DNA N-glycosylase activity DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine). go-plus.json hypoxanthine-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0097507 GO:0097506 biolink:MolecularActivity deaminated base DNA N-glycosylase activity DNA N-glycosylase activity acting on deaminated bases. go-plus.json deaminated base DNA glycosylase activity|DNA glycosylase activity acting on deaminated bases http://purl.obolibrary.org/obo/GO_0097506 GO:0097501 biolink:BiologicalProcess stress response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus. go-plus.json response to metal toxicity|response to metal ion stress|response to metal ion toxicity|response to excess metal ion http://purl.obolibrary.org/obo/GO_0097501 GO:0097500 biolink:BiologicalProcess receptor localization to non-motile cilium A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium. go-plus.json receptor localization to nonmotile primary cilium http://purl.obolibrary.org/obo/GO_0097500 GO:0097503 biolink:BiologicalProcess sialylation The covalent attachment of sialic acid to a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0097503 GO:0097502 biolink:BiologicalProcess mannosylation The covalent attachment of a mannose residue to a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0097502 GO:0097552 biolink:BiologicalProcess mitochondrial double-strand break repair via homologous recombination The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences. go-plus.json mtDSB repair via homologous recombination http://purl.obolibrary.org/obo/GO_0097552 GO:0097551 biolink:BiologicalProcess mitochondrial double-strand break repair The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. go-plus.json mtDSB repair http://purl.obolibrary.org/obo/GO_0097551 GO:0097554 biolink:CellularComponent left anterior flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell. go-plus.json left anterior cilium http://purl.obolibrary.org/obo/GO_0097554 GO:0097553 biolink:BiologicalProcess calcium ion transmembrane import into cytosol A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore. go-plus.json calcium transmembrane import into cytosol http://purl.obolibrary.org/obo/GO_0097553 GO:0097550 biolink:CellularComponent transcription preinitiation complex A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription. go-plus.json transcription preinitiation complex|DNA-templated transcriptional preinitiation complex|transcriptional pre-initiation complex|preinitiation complex|PIC|transcriptional preinitiation complex http://purl.obolibrary.org/obo/GO_0097550 CHEBI:48096 biolink:ChemicalSubstance D-glutamic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_48096 CHEBI:48095 biolink:ChemicalSubstance keto-D-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48095 chebi_ph7_3 CHEBI:48097 biolink:ChemicalSubstance D-glutamine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_48097 CHEBI:133892 biolink:ChemicalSubstance 4-O-[1-D-ribitylphosphonato-(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133892 chebi_ph7_3 CHEBI:133894 biolink:ChemicalSubstance 4-O-[poly(1-D-ribitylphosphonato)-1-D-ribitylphosphonato-(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133894 chebi_ph7_3 CHEBI:133897 biolink:ChemicalSubstance methanesulfinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133897 CHEBI:133896 biolink:ChemicalSubstance 4-O-({poly[1-D-ribitylphosphonato]}-di{[2R]-1-glycerylphosphonato})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133896 chebi_ph7_3 CHEBI:133899 biolink:ChemicalSubstance 8(S),15(S)-DiHPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133899 chebi_ph7_3 CHEBI:133898 biolink:ChemicalSubstance chromopyrrolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133898 chebi_ph7_3 GO:0097559 biolink:CellularComponent right ventral flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc. go-plus.json right ventral cilium http://purl.obolibrary.org/obo/GO_0097559 GO:0097556 biolink:CellularComponent left posteriolateral flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body. go-plus.json left posterolateral cilium|left posterolateral flagellum|left posteriolateral cilium http://purl.obolibrary.org/obo/GO_0097556 GO:0097555 biolink:CellularComponent right anterior flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell. go-plus.json right anterior cilium http://purl.obolibrary.org/obo/GO_0097555 GO:0097558 biolink:CellularComponent left ventral flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc. go-plus.json left ventral cilium http://purl.obolibrary.org/obo/GO_0097558 GO:0097557 biolink:CellularComponent right posteriolateral flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body. go-plus.json right posterolateral flagellum|right posterolateral cilium|right posteriolateral cilium http://purl.obolibrary.org/obo/GO_0097557 GO:0097563 biolink:CellularComponent left middle basal body pair Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally. go-plus.json http://purl.obolibrary.org/obo/GO_0097563 GO:0097562 biolink:CellularComponent left lateral basal body pair Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally. go-plus.json http://purl.obolibrary.org/obo/GO_0097562 GO:0097565 biolink:CellularComponent right middle basal body pair Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally. go-plus.json http://purl.obolibrary.org/obo/GO_0097565 GO:0097564 biolink:CellularComponent right lateral basal body pair Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally. go-plus.json http://purl.obolibrary.org/obo/GO_0097564 GO:0097561 biolink:CellularComponent right caudal flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body. go-plus.json right caudal cilium http://purl.obolibrary.org/obo/GO_0097561 GO:0097560 biolink:CellularComponent left caudal flagellum A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body. go-plus.json left caudal cilium http://purl.obolibrary.org/obo/GO_0097560 CHEBI:48092 biolink:ChemicalSubstance L-xylonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48092 CHEBI:48094 biolink:ChemicalSubstance D-aspartic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_48094 CHEBI:48093 biolink:ChemicalSubstance D-xylonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48093 GO:0097567 biolink:CellularComponent right tetrad Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally). go-plus.json http://purl.obolibrary.org/obo/GO_0097567 GO:0097566 biolink:CellularComponent left tetrad Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally). go-plus.json http://purl.obolibrary.org/obo/GO_0097566 GO:0097569 biolink:CellularComponent lateral shield Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella. go-plus.json http://purl.obolibrary.org/obo/GO_0097569 GO:0097568 biolink:CellularComponent median body A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc. go-plus.json parabasal body http://purl.obolibrary.org/obo/GO_0097568 GO:0097530 biolink:BiologicalProcess granulocyte migration The movement of a granulocyte within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0097530 GO:0097532 biolink:BiologicalProcess stress response to acid chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. go-plus.json response to acid stress|stress response to acid http://purl.obolibrary.org/obo/GO_0097532 GO:0097531 biolink:BiologicalProcess mast cell migration The movement of a mast cell within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0097531 CHEBI:133872 biolink:ChemicalSubstance (2Z,4E)-4-hydroxy-6-oxoocta-2,4-dienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133872 CHEBI:48081 biolink:ChemicalSubstance bacteriocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48081 CHEBI:48080 biolink:ChemicalSubstance brefeldin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_48080 chebi_ph7_3 NCBITaxon:36826 biolink:OrganismalEntity Clostridium botulinum A go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_36826 GO:0097538 biolink:CellularComponent ciliary necklace A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links. go-plus.json cilial necklace|cilium necklace http://purl.obolibrary.org/obo/GO_0097538 GO:0097537 biolink:CellularComponent Y-shaped link A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium. go-plus.json Y-shaped assemblage|Y-shaped linker|Y-link|Y-shaped fibre|membrane-microtubule complex|Y-shaped fiber|Y-link structure http://purl.obolibrary.org/obo/GO_0097537 GO:0097539 biolink:CellularComponent ciliary transition fiber A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium). go-plus.json cilial transition fiber|distal appendage of basal body|cilium transition fibre|centriolar distal appendage|cilium transition fiber|ciliary transition fibre|transition fibre|distal appendage of mother centriole|distal appendage of centriole|cilial transition fibre|transition fiber http://purl.obolibrary.org/obo/GO_0097539 GO:0097534 biolink:BiologicalProcess lymphoid lineage cell migration The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage. go-plus.json lymphoid lineage restricted progenitor cell migration http://purl.obolibrary.org/obo/GO_0097534 GO:0097533 biolink:BiologicalProcess cellular stress response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. go-plus.json cellular response to acid stress|cellular stress response to acid http://purl.obolibrary.org/obo/GO_0097533 GO:0097536 biolink:BiologicalProcess thymus epithelium morphogenesis The process in which the thymus epithelium is generated and organized. go-plus.json thymic epithelium morphogenesis http://purl.obolibrary.org/obo/GO_0097536 GO:0097535 biolink:BiologicalProcess lymphoid lineage cell migration into thymus The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process. go-plus.json lymphoid lineage restricted progenitor cell migration into thymus http://purl.obolibrary.org/obo/GO_0097535 GO:0097541 biolink:CellularComponent axonemal basal plate Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure. go-plus.json axoneme basal plate|basal plate http://purl.obolibrary.org/obo/GO_0097541 GO:0097540 biolink:CellularComponent axonemal central pair Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia. go-plus.json central pair|axoneme microtubule central pair|central-pair microtubules|axonemal microtubule central pair|axoneme central pair http://purl.obolibrary.org/obo/GO_0097540 GO:0097543 biolink:CellularComponent ciliary inversin compartment Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium. go-plus.json cilial inversin compartment|flagellum inversin compartment|Inv compartment of the cilium|cilium inversin compartment|flagellar inversin compartment|inversin compartment http://purl.obolibrary.org/obo/GO_0097543 GO:0097542 biolink:CellularComponent ciliary tip Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction. go-plus.json cilium tip|flagellum tip|cilial tip|flagellar tip http://purl.obolibrary.org/obo/GO_0097542 CHEBI:48066 biolink:ChemicalSubstance D-mannopyranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48066 CHEBI:48069 biolink:ChemicalSubstance (R)-5-oxo-2,5-dihydro-2-furylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48069 CHEBI:48068 biolink:ChemicalSubstance (S)-5-oxo-2,5-dihydro-2-furylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48068 CHEBI:133886 biolink:ChemicalSubstance FMNH2(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133886 CHEBI:48070 biolink:ChemicalSubstance 12-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48070 GO:0097549 biolink:BiologicalProcess obsolete chromatin organization involved in negative regulation of transcription OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization. go-plus.json negative regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|negative regulation of global transcription from Pol II promoter by histone modification|negative regulation of transcription by chromatin organization|negative regulation of transcription from Pol II promoter by histone modification|negative regulation of transcription from RNA polymerase II promoter, global by histone modification|negative regulation of transcription from RNA polymerase II promoter by histone modification http://purl.obolibrary.org/obo/GO_0097549 GO:0097548 biolink:BiologicalProcess seed abscission The controlled shedding of a seed. go-plus.json http://purl.obolibrary.org/obo/GO_0097548 GO:0097545 biolink:CellularComponent axonemal outer doublet Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium. go-plus.json outer doublet|outer-doublet microtubules|axoneme outer doublet http://purl.obolibrary.org/obo/GO_0097545 GO:0097544 biolink:CellularComponent ciliary shaft The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space. go-plus.json cilium shaft|flagellum shaft|cilial shaft|flagellar shaft http://purl.obolibrary.org/obo/GO_0097544 GO:0097547 biolink:CellularComponent synaptic vesicle protein transport vesicle A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon. go-plus.json STV http://purl.obolibrary.org/obo/GO_0097547 GO:0097546 biolink:CellularComponent ciliary base Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area. go-plus.json cilium base|flagellar base|cilial base|flagellum base http://purl.obolibrary.org/obo/GO_0097546 GO:1903908 biolink:BiologicalProcess positive regulation of plasma membrane raft polarization Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization. go-plus.json up-regulation of plasma membrane raft polarization|upregulation of plasma membrane raft polarization|up regulation of plasma membrane raft polarization|activation of plasma membrane raft polarization http://purl.obolibrary.org/obo/GO_1903908 GO:1903907 biolink:BiologicalProcess negative regulation of plasma membrane raft polarization Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization. go-plus.json inhibition of plasma membrane raft polarization|down regulation of plasma membrane raft polarization|downregulation of plasma membrane raft polarization|down-regulation of plasma membrane raft polarization http://purl.obolibrary.org/obo/GO_1903907 GO:1903906 biolink:BiologicalProcess regulation of plasma membrane raft polarization Any process that modulates the frequency, rate or extent of plasma membrane raft polarization. go-plus.json http://purl.obolibrary.org/obo/GO_1903906 GO:1903905 biolink:BiologicalProcess positive regulation of establishment of T cell polarity Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. go-plus.json up-regulation of T lymphocyte polarization|upregulation of establishment of T lymphocyte polarity|up-regulation of T cell polarization|up regulation of T-cell polarization|positive regulation of establishment of T-lymphocyte polarity|activation of T-cell polarization|positive regulation of T-cell polarization|up regulation of establishment of T-lymphocyte polarity|upregulation of establishment of T cell polarity|positive regulation of establishment of T-cell polarity|upregulation of T lymphocyte polarization|up regulation of establishment of T-cell polarity|up-regulation of establishment of T lymphocyte polarity|activation of establishment of T lymphocyte polarity|upregulation of T cell polarization|upregulation of establishment of T-lymphocyte polarity|activation of establishment of T cell polarity|up-regulation of establishment of T cell polarity|up-regulation of T-cell polarization|up regulation of T lymphocyte polarization|activation of T lymphocyte polarization|upregulation of establishment of T-cell polarity|positive regulation of T lymphocyte polarization|up regulation of T cell polarization|positive regulation of establishment of T lymphocyte polarity|activation of T cell polarization|positive regulation of T cell polarization|up-regulation of establishment of T-lymphocyte polarity|up regulation of establishment of T lymphocyte polarity|activation of establishment of T-lymphocyte polarity|upregulation of T-cell polarization|up-regulation of establishment of T-cell polarity|up regulation of establishment of T cell polarity|activation of establishment of T-cell polarity http://purl.obolibrary.org/obo/GO_1903905 CHEBI:73017 biolink:ChemicalSubstance O-isobutyrylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73017 chebi_ph7_3 GO:1903904 biolink:BiologicalProcess negative regulation of establishment of T cell polarity Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity. go-plus.json downregulation of T-cell polarization|inhibition of establishment of T lymphocyte polarity|negative regulation of establishment of T-cell polarity|down-regulation of establishment of T-cell polarity|down regulation of establishment of T cell polarity|inhibition of T cell polarization|inhibition of establishment of T cell polarity|downregulation of establishment of T-lymphocyte polarity|negative regulation of T-cell polarization|down-regulation of T-cell polarization|down regulation of T lymphocyte polarization|down regulation of establishment of T-lymphocyte polarity|downregulation of establishment of T-cell polarity|inhibition of establishment of T-lymphocyte polarity|down regulation of T cell polarization|downregulation of T lymphocyte polarization|down regulation of establishment of T-cell polarity|inhibition of T-cell polarization|down-regulation of establishment of T lymphocyte polarity|inhibition of establishment of T-cell polarity|negative regulation of establishment of T lymphocyte polarity|downregulation of T cell polarization|down-regulation of establishment of T cell polarity|down-regulation of T lymphocyte polarization|negative regulation of T lymphocyte polarization|downregulation of establishment of T lymphocyte polarity|negative regulation of T cell polarization|down regulation of T-cell polarization|down-regulation of T cell polarization|inhibition of T lymphocyte polarization|down-regulation of establishment of T-lymphocyte polarity|negative regulation of establishment of T-lymphocyte polarity|down regulation of establishment of T lymphocyte polarity|downregulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_1903904 GO:1903903 biolink:BiologicalProcess regulation of establishment of T cell polarity Any process that modulates the frequency, rate or extent of establishment of T cell polarity. go-plus.json regulation of establishment of T-lymphocyte polarity|regulation of T lymphocyte polarization|regulation of establishment of T-cell polarity|regulation of T cell polarization|regulation of establishment of T lymphocyte polarity|regulation of T-cell polarization http://purl.obolibrary.org/obo/GO_1903903 GO:1903902 biolink:BiologicalProcess positive regulation of viral life cycle Any process that activates or increases the frequency, rate or extent of viral life cycle. go-plus.json up-regulation of viral infectious cycle|activation of viral replication|activation of lytic viral life cycle|upregulation of viral assembly, maturation, egress, and release|up regulation of viral life cycle|activation of viral infectious cycle|positive regulation of lytic viral life cycle|up-regulation of viral replication|positive regulation of viral infectious cycle|up regulation of lytic viral life cycle|up regulation of viral infectious cycle|upregulation of viral life cycle|up regulation of viral assembly, maturation, egress, and release|positive regulation of viral assembly, maturation, egress, and release|upregulation of viral replication|upregulation of lytic viral life cycle|activation of viral assembly, maturation, egress, and release|upregulation of viral infectious cycle|up-regulation of viral life cycle|activation of viral life cycle|up regulation of viral replication|up-regulation of viral assembly, maturation, egress, and release|positive regulation of viral replication|up-regulation of lytic viral life cycle http://purl.obolibrary.org/obo/GO_1903902 GO:1903901 biolink:BiologicalProcess negative regulation of viral life cycle Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle. go-plus.json inhibition of viral assembly, maturation, egress, and release|down-regulation of viral replication|negative regulation of viral replication|down-regulation of lytic viral life cycle|negative regulation of lytic viral life cycle|down-regulation of viral infectious cycle|negative regulation of viral infectious cycle|down regulation of viral assembly, maturation, egress, and release|downregulation of viral life cycle|down regulation of viral life cycle|downregulation of viral assembly, maturation, egress, and release|downregulation of lytic viral life cycle|inhibition of viral life cycle|inhibition of viral replication|downregulation of viral infectious cycle|down regulation of lytic viral life cycle|down regulation of viral infectious cycle|down-regulation of viral assembly, maturation, egress, and release|down regulation of viral replication|negative regulation of viral assembly, maturation, egress, and release|downregulation of viral replication|inhibition of lytic viral life cycle|inhibition of viral infectious cycle|down-regulation of viral life cycle http://purl.obolibrary.org/obo/GO_1903901 GO:1903900 biolink:BiologicalProcess regulation of viral life cycle Any process that modulates the frequency, rate or extent of viral life cycle. go-plus.json regulation of viral assembly, maturation, egress, and release|regulation of lytic viral life cycle|regulation of viral infectious cycle|regulation of viral replication http://purl.obolibrary.org/obo/GO_1903900 GO:0048505 biolink:BiologicalProcess regulation of timing of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development. go-plus.json timing of cell differentiation http://purl.obolibrary.org/obo/GO_0048505 CHEBI:63693 biolink:ChemicalSubstance (2Z,4Z)-2-hydroxyhexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63693 chebi_ph7_3 GO:0048504 biolink:BiologicalProcess regulation of timing of animal organ formation Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development. go-plus.json timing of organ formation|timing of organ biosynthesis http://purl.obolibrary.org/obo/GO_0048504 CHEBI:63692 biolink:ChemicalSubstance 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63692 chebi_ph7_3 GO:0048503 biolink:MolecularActivity obsolete GPI anchor binding OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes. go-plus.json GPI anchor binding|glycosylphosphatidylinositol binding http://purl.obolibrary.org/obo/GO_0048503 GO:0048502 biolink:MolecularActivity ABC-type thiamine transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in). TC:3.A.1.19.1|EC:7.6.2.15|RHEA:29811 go-plus.json thiamine pyrophosphate-transporting ATPase activity|thiamine-transporting ATPase activity|TPP transporting ATPase activity|thiamine ABC transporter|thiamin pyrophosphate ABC transporter|thiamin-transporting ATPase activity|thiamin pyrophosphate porter activity|thiamin pyrophosphate transporting ATPase activity|ATP-dependent thiamine transmembrane transporter activity|ATPase-coupled thiamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0048502 CHEBI:63690 biolink:ChemicalSubstance (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63690 chebi_ph7_3 GO:0048501 biolink:CellularComponent signal recognition particle, plasma membrane targeting A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0048501 GO:0048500 biolink:CellularComponent signal recognition particle A complex of protein and RNA which facilitates translocation of proteins across membranes. Wikipedia:Signal_recognition_particle go-plus.json http://purl.obolibrary.org/obo/GO_0048500 goslim_metagenomics|goslim_pir CHEBI:63696 biolink:ChemicalSubstance gamma-curcumene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63696 chebi_ph7_3 CHEBI:63694 biolink:ChemicalSubstance D-synephrine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63694 chebi_ph7_3 GO:0048509 biolink:BiologicalProcess regulation of meristem development Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048509 GO:0048508 biolink:BiologicalProcess embryonic meristem development The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048508 GO:0048507 biolink:BiologicalProcess meristem development The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048507 GO:0048506 biolink:BiologicalProcess regulation of timing of meristematic phase transition Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point. go-plus.json http://purl.obolibrary.org/obo/GO_0048506 PO:0025417 biolink:OntologyClass xylem vessel A portion of xylem (PO:0005352) tissue that has as parts a tube-like series of vessel members (PO:0002003), the common walls of which have perforations. go-plus.json vaso xilem&$225tico (Spanish, exact)|木質部導管 (Japanese, exact)|vessel (exact) http://purl.obolibrary.org/obo/PO_0025417 PO:0025416 biolink:OntologyClass sieve tube A portion of phloem tissue (PO:0005417) that has as parts a series of sieve tube elements (PO:0000289) arranged end to end and interconnected through sieve plates. go-plus.json 師(篩）管 (Japanese, exact)|tubo criboso (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025416 PO:0025415 biolink:OntologyClass sieve cell A sieve element (PO:0025406) in which the sieve areas are not aggregated into sieve plates (GO:0097218). go-plus.json célula cribosa (Spanish, exact)|師（篩）細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025415 CHEBI:73011 biolink:ChemicalSubstance germacranolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_73011 GO:1903909 biolink:BiologicalProcess regulation of receptor clustering Any process that modulates the frequency, rate or extent of receptor clustering. go-plus.json http://purl.obolibrary.org/obo/GO_1903909 GO:1903919 biolink:BiologicalProcess negative regulation of actin filament severing Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing. go-plus.json inhibition of actin filament severing activity|down regulation of actin filament severing|down-regulation of barbed-end actin capping/severing activity|negative regulation of F-actin severing|negative regulation of barbed-end actin capping/severing activity|down-regulation of F-actin severing|downregulation of actin filament severing|down-regulation of actin filament severing activity|downregulation of F-actin severing|downregulation of barbed-end actin capping/severing activity|negative regulation of actin filament severing activity|down-regulation of actin filament severing|down regulation of F-actin severing|down regulation of barbed-end actin capping/severing activity|inhibition of F-actin severing|inhibition of actin filament severing|downregulation of actin filament severing activity|inhibition of barbed-end actin capping/severing activity|down regulation of actin filament severing activity http://purl.obolibrary.org/obo/GO_1903919 GO:1903918 biolink:BiologicalProcess regulation of actin filament severing Any process that modulates the frequency, rate or extent of actin filament severing. go-plus.json regulation of F-actin severing|regulation of barbed-end actin capping/severing activity|regulation of actin filament severing activity http://purl.obolibrary.org/obo/GO_1903918 CHEBI:73026 biolink:ChemicalSubstance 2-methylbutyrylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73026 chebi_ph7_3 GO:1903917 biolink:BiologicalProcess positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation. go-plus.json up regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of eIF2alpha dephosphorylation in response to ER stress|activation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of ER stress-induced eIF2 alpha dephosphorylation|upregulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of eIF2alpha dephosphorylation in response to ER stress http://purl.obolibrary.org/obo/GO_1903917 CHEBI:73029 biolink:ChemicalSubstance maackiain go-plus.json http://purl.obolibrary.org/obo/CHEBI_73029 chebi_ph7_3 GO:1903916 biolink:BiologicalProcess regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation. go-plus.json regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|regulation of ER stress-induced eIF2 alpha dephosphorylation|regulation of eIF2alpha dephosphorylation in response to ER stress|regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_1903916 GO:1903915 biolink:BiologicalProcess positive regulation of fusion of virus membrane with host plasma membrane Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane. go-plus.json activation of viral-cell fusion molecule activity|upregulation of fusion of virus membrane with host plasma membrane|upregulation of viral envelope fusion with host cell membrane|upregulation of viral envelope fusion with host plasma membrane|upregulation of viral envelope fusion with host membrane|up-regulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral-cell fusion molecule activity|up regulation of viral penetration via membrane fusion|up-regulation of fusion of virus membrane with host plasma membrane|activation of fusion of virus membrane with host plasma membrane|positive regulation of viral penetration via membrane fusion|activation of viral penetration via membrane fusion|up regulation of viral envelope fusion with host plasma membrane|up regulation of viral envelope fusion with host cell membrane|upregulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral envelope fusion with host membrane|positive regulation of viral envelope fusion with host cell membrane|activation of viral envelope fusion with host membrane|activation of viral envelope fusion with host cell membrane|positive regulation of viral envelope fusion with host plasma membrane|activation of viral envelope fusion with host plasma membrane|upregulation of viral-cell fusion molecule activity|up-regulation of viral penetration via membrane fusion|up regulation of viral entry into host cell via membrane fusion with the plasma membrane|up regulation of fusion of virus membrane with host plasma membrane|positive regulation of viral envelope fusion with host membrane|up-regulation of viral envelope fusion with host cell membrane|positive regulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral envelope fusion with host plasma membrane|up regulation of viral-cell fusion molecule activity|up regulation of viral envelope fusion with host membrane|positive regulation of viral-cell fusion molecule activity|activation of viral entry into host cell via membrane fusion with the plasma membrane|upregulation of viral penetration via membrane fusion http://purl.obolibrary.org/obo/GO_1903915 GO:1903914 biolink:BiologicalProcess negative regulation of fusion of virus membrane with host plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane. go-plus.json down regulation of viral envelope fusion with host membrane|down regulation of viral penetration via membrane fusion|inhibition of viral envelope fusion with host membrane|down regulation of viral envelope fusion with host cell membrane|down regulation of viral envelope fusion with host plasma membrane|downregulation of viral penetration via membrane fusion|downregulation of viral envelope fusion with host plasma membrane|downregulation of viral envelope fusion with host cell membrane|inhibition of viral entry into host cell via membrane fusion with the plasma membrane|inhibition of viral-cell fusion molecule activity|negative regulation of viral penetration via membrane fusion|down-regulation of viral penetration via membrane fusion|down regulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of fusion of virus membrane with host plasma membrane|down-regulation of viral envelope fusion with host cell membrane|negative regulation of viral envelope fusion with host plasma membrane|negative regulation of viral envelope fusion with host cell membrane|down-regulation of viral envelope fusion with host plasma membrane|down regulation of viral-cell fusion molecule activity|downregulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of viral envelope fusion with host membrane|negative regulation of viral envelope fusion with host membrane|inhibition of viral penetration via membrane fusion|downregulation of viral-cell fusion molecule activity|inhibition of viral envelope fusion with host cell membrane|inhibition of viral envelope fusion with host plasma membrane|downregulation of fusion of virus membrane with host plasma membrane|downregulation of viral envelope fusion with host membrane|negative regulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of viral entry into host cell via membrane fusion with the plasma membrane|down regulation of fusion of virus membrane with host plasma membrane|inhibition of fusion of virus membrane with host plasma membrane|negative regulation of viral-cell fusion molecule activity|down-regulation of viral-cell fusion molecule activity http://purl.obolibrary.org/obo/GO_1903914 GO:1903913 biolink:BiologicalProcess regulation of fusion of virus membrane with host plasma membrane Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane. go-plus.json regulation of viral penetration via membrane fusion|regulation of viral envelope fusion|regulation of viral envelope fusion with host plasma membrane|regulation of viral envelope fusion with host cell membrane|regulation of viral entry into host cell via membrane fusion with the plasma membrane|regulation of viral-cell fusion molecule activity|regulation of viral envelope fusion with host membrane http://purl.obolibrary.org/obo/GO_1903913 GO:1903912 biolink:BiologicalProcess negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation. go-plus.json downregulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|downregulation of eiF2alpha phosphorylation in response to ER stress|down-regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of eiF2alpha phosphorylation in response to ER stress|inhibition of eiF2alpha phosphorylation in response to ER stress|inhibition of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of ER stress-induced eIF2 alpha phosphorylation|down regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of eiF2alpha phosphorylation in response to ER stress|negative regulation of eiF2alpha phosphorylation in response to ER stress|downregulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_1903912 GO:1903911 biolink:BiologicalProcess positive regulation of receptor clustering Any process that activates or increases the frequency, rate or extent of receptor clustering. go-plus.json upregulation of receptor clustering|up regulation of receptor clustering|activation of receptor clustering|up-regulation of receptor clustering http://purl.obolibrary.org/obo/GO_1903911 GO:0048516 biolink:BiologicalProcess obsolete trichome initiation (sensu Magnoliophyta) OBSOLETE. Processes causing the differentiation of an epidermal cell into a trichome cell; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398). go-plus.json trichome initiation (sensu Magnoliophyta) http://purl.obolibrary.org/obo/GO_0048516 GO:1903910 biolink:BiologicalProcess negative regulation of receptor clustering Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering. go-plus.json down regulation of receptor clustering|downregulation of receptor clustering|down-regulation of receptor clustering|inhibition of receptor clustering http://purl.obolibrary.org/obo/GO_1903910 GO:0048515 biolink:BiologicalProcess spermatid differentiation The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json spermatid cell differentiation http://purl.obolibrary.org/obo/GO_0048515 GO:0048514 biolink:BiologicalProcess blood vessel morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. go-plus.json http://purl.obolibrary.org/obo/GO_0048514 GO:0048513 biolink:BiologicalProcess animal organ development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. Wikipedia:Organogenesis go-plus.json organogenesis|development of an organ http://purl.obolibrary.org/obo/GO_0048513 GO:0048512 biolink:BiologicalProcess circadian behavior The specific behavior of an organism that recurs with a regularity of approximately 24 hours. go-plus.json circadian rhythm behavior http://purl.obolibrary.org/obo/GO_0048512 CHEBI:87653 biolink:ChemicalSubstance (25R)-3beta,26-dihydroxycholest-5-en-7-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87653 chebi_ph7_3 GO:0048511 biolink:BiologicalProcess rhythmic process Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. go-plus.json rhythm http://purl.obolibrary.org/obo/GO_0048511 goslim_pir GO:0048510 biolink:BiologicalProcess regulation of timing of transition from vegetative to reproductive phase The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0048510 CHEBI:87657 biolink:ChemicalSubstance octanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_87657 chebi_ph7_3 CHEBI:87656 biolink:ChemicalSubstance hexanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_87656 chebi_ph7_3 CHEBI:87659 biolink:ChemicalSubstance dodecanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_87659 chebi_ph7_3 CHEBI:87658 biolink:ChemicalSubstance decanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_87658 chebi_ph7_3 GO:0048519 biolink:BiologicalProcess negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. go-plus.json down-regulation of biological process|downregulation of biological process|negative regulation of physiological process|down regulation of biological process|inhibition of biological process http://purl.obolibrary.org/obo/GO_0048519 gocheck_do_not_annotate GO:0048518 biolink:BiologicalProcess positive regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. go-plus.json up-regulation of biological process|activation of biological process|up regulation of biological process|positive regulation of physiological process|upregulation of biological process|stimulation of biological process http://purl.obolibrary.org/obo/GO_0048518 gocheck_do_not_annotate GO:0048517 biolink:BiologicalProcess obsolete positive regulation of trichome initiation (sensu Magnoliophyta) OBSOLETE. Any process that activates or increases the frequency, rate or extent of trichome initiation; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398). go-plus.json positive regulation of trichome initiation (sensu Magnoliophyta) http://purl.obolibrary.org/obo/GO_0048517 PO:0025406 biolink:OntologyClass sieve element A native plant cell (PO:0025606) that is part of a portion of phloem tissue (PO:0005417), has sieve areas in its walls, and lacks a nucleus in its mature protoplast. go-plus.json elemento criboso (Spanish, exact)|師(篩）要素 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025406 CHEBI:73025 biolink:ChemicalSubstance O-isovalerylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73025 chebi_ph7_3 CHEBI:73024 biolink:ChemicalSubstance O-acetylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73024 chebi_ph7_3 GO:1903929 biolink:BiologicalProcess primary palate development The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure. go-plus.json palatum primarium development|primitive palate development|processus palatinus medianus development|primary palate process development http://purl.obolibrary.org/obo/GO_1903929 GO:1903928 biolink:BiologicalProcess cellular response to cyanide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903928 GO:1903927 biolink:BiologicalProcess response to cyanide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903927 CHEBI:73039 biolink:ChemicalSubstance O-octanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73039 chebi_ph7_3 GO:1903926 biolink:BiologicalProcess cellular response to bisphenol A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903926 GO:1903925 biolink:BiologicalProcess response to bisphenol A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903925 GO:1903924 biolink:MolecularActivity estradiol binding Binding to estradiol. go-plus.json http://purl.obolibrary.org/obo/GO_1903924 GO:1903923 biolink:BiologicalProcess positive regulation of protein processing in phagocytic vesicle Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle. go-plus.json up regulation of protein maturation by peptide bond hydrolysis in phagosome|up-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of protein maturation by proteolysis in phagosome|up-regulation of protein maturation by peptide bond cleavage in phagosome|up regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up-regulation of protein maturation by proteolysis in phagocytic vesicle|activation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up-regulation of protein processing in phagocytic vesicle|upregulation of peptidolysis during protein maturation in phagosome|activation of protein processing in phagocytic vesicle|upregulation of protein processing in phagosome|upregulation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up-regulation of protein maturation by proteolysis in phagosome|upregulation of protein maturation by peptide bond hydrolysis in phagosome|upregulation of protein maturation by proteolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond cleavage in phagosome|up regulation of peptidolysis during protein maturation in phagosome|up-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up regulation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by proteolysis in phagosome|positive regulation of peptidolysis during protein maturation in phagosome|up regulation of protein processing in phagosome|up-regulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of protein processing in phagocytic vesicle|positive regulation of protein processing in phagosome|activation of protein processing in phagosome|up regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up-regulation of protein maturation by peptide bond hydrolysis in phagosome|activation of protein maturation by peptide bond hydrolysis in phagosome|positive regulation of protein maturation by proteolysis in phagosome|up regulation of protein maturation by proteolysis in phagocytic vesicle|activation of protein maturation by peptide bond cleavage in phagocytic vesicle|activation of peptidolysis during protein maturation in phagosome|positive regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up regulation of protein maturation by proteolysis in phagosome|activation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|positive regulation of protein maturation by proteolysis in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagosome|up-regulation of peptidolysis during protein maturation in phagosome|upregulation of protein processing in phagocytic vesicle|positive regulation of peptidolysis during protein maturation in phagocytic vesicle|activation of protein maturation by proteolysis in phagocytic vesicle|up regulation of peptidolysis during protein maturation in phagocytic vesicle|up-regulation of protein processing in phagosome|positive regulation of protein maturation by peptide bond hydrolysis in phagosome http://purl.obolibrary.org/obo/GO_1903923 GO:0048527 biolink:BiologicalProcess lateral root development The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper. go-plus.json http://purl.obolibrary.org/obo/GO_0048527 GO:1903922 biolink:BiologicalProcess negative regulation of protein processing in phagocytic vesicle Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle. go-plus.json inhibition of protein maturation by proteolysis in phagosome|downregulation of protein maturation by peptide bond hydrolysis in phagosome|down regulation of peptidolysis during protein maturation in phagocytic vesicle|down regulation of peptidolysis during protein maturation in phagosome|inhibition of protein maturation by proteolysis in phagocytic vesicle|down regulation of protein maturation by peptide bond hydrolysis in phagosome|down-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|negative regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|inhibition of protein maturation by peptide bond hydrolysis in phagosome|negative regulation of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein maturation by peptide bond cleavage in phagosome|down regulation of protein processing in phagosome|inhibition of peptidolysis during protein maturation in phagocytic vesicle|downregulation of peptidolysis during protein maturation in phagosome|down-regulation of protein processing in phagocytic vesicle|down regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|downregulation of protein processing in phagosome|down regulation of protein maturation by proteolysis in phagocytic vesicle|inhibition of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down-regulation of protein maturation by proteolysis in phagosome|negative regulation of protein maturation by proteolysis in phagosome|downregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|downregulation of protein maturation by proteolysis in phagocytic vesicle|downregulation of protein maturation by peptide bond cleavage in phagosome|negative regulation of peptidolysis during protein maturation in phagosome|down-regulation of peptidolysis during protein maturation in phagosome|downregulation of protein processing in phagocytic vesicle|down regulation of protein maturation by peptide bond cleavage in phagosome|down-regulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein processing in phagosome|negative regulation of peptidolysis during protein maturation in phagocytic vesicle|negative regulation of protein processing in phagosome|downregulation of protein maturation by proteolysis in phagosome|down regulation of protein processing in phagocytic vesicle|negative regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|inhibition of protein processing in phagocytic vesicle|down-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|negative regulation of protein maturation by proteolysis in phagocytic vesicle|down-regulation of protein maturation by proteolysis in phagocytic vesicle|down regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down-regulation of protein maturation by peptide bond hydrolysis in phagosome|negative regulation of protein maturation by peptide bond hydrolysis in phagosome|down regulation of protein maturation by proteolysis in phagosome|inhibition of protein processing in phagosome|downregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|inhibition of peptidolysis during protein maturation in phagosome|downregulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein maturation by peptide bond cleavage in phagocytic vesicle http://purl.obolibrary.org/obo/GO_1903922 GO:1903921 biolink:BiologicalProcess regulation of protein processing in phagocytic vesicle Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle. go-plus.json regulation of peptidolysis during protein maturation in phagocytic vesicle|regulation of protein maturation by peptide bond hydrolysis in phagosome|regulation of peptidolysis during protein maturation in phagosome|regulation of protein processing in phagosome|regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|regulation of protein maturation by proteolysis in phagocytic vesicle|regulation of protein maturation by peptide bond cleavage in phagosome|regulation of protein maturation by proteolysis in phagosome|regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle http://purl.obolibrary.org/obo/GO_1903921 GO:0048526 biolink:BiologicalProcess imaginal disc-derived wing expansion The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing. go-plus.json wing inflation|wing expansion http://purl.obolibrary.org/obo/GO_0048526 GO:1903920 biolink:BiologicalProcess positive regulation of actin filament severing Any process that activates or increases the frequency, rate or extent of actin filament severing. go-plus.json up regulation of actin filament severing activity|upregulation of barbed-end actin capping/severing activity|upregulation of F-actin severing|up-regulation of actin filament severing|activation of F-actin severing|upregulation of actin filament severing activity|up-regulation of F-actin severing|up-regulation of barbed-end actin capping/severing activity|upregulation of actin filament severing|activation of barbed-end actin capping/severing activity|up-regulation of actin filament severing activity|positive regulation of F-actin severing|positive regulation of barbed-end actin capping/severing activity|up regulation of actin filament severing|up regulation of barbed-end actin capping/severing activity|up regulation of F-actin severing|activation of actin filament severing|activation of actin filament severing activity|positive regulation of actin filament severing activity http://purl.obolibrary.org/obo/GO_1903920 GO:0048525 biolink:BiologicalProcess negative regulation of viral process Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant. go-plus.json negative regulation of viral reproduction|negative regulation of viral life cycle|down-regulation of viral life cycle|downregulation of viral life cycle|down regulation of viral life cycle|inhibition of viral life cycle http://purl.obolibrary.org/obo/GO_0048525 GO:0048524 biolink:BiologicalProcess positive regulation of viral process Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant. go-plus.json up-regulation of viral life cycle|stimulation of viral life cycle|positive regulation of viral reproduction|positive regulation of viral life cycle|activation of viral life cycle|up regulation of viral life cycle|upregulation of viral life cycle http://purl.obolibrary.org/obo/GO_0048524 GO:0048523 biolink:BiologicalProcess negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. go-plus.json down-regulation of cellular process|downregulation of cellular process|down regulation of cellular process|inhibition of cellular process|negative regulation of cellular physiological process http://purl.obolibrary.org/obo/GO_0048523 GO:0048522 biolink:BiologicalProcess positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. go-plus.json stimulation of cellular process|activation of cellular process|up-regulation of cellular process|up regulation of cellular process|upregulation of cellular process|positive regulation of cellular physiological process http://purl.obolibrary.org/obo/GO_0048522 CHEBI:14737 biolink:ChemicalSubstance pantoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_14737 GO:0048521 biolink:BiologicalProcess negative regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. go-plus.json inhibition of behavior|down-regulation of behavior|downregulation of behavior|down regulation of behavior http://purl.obolibrary.org/obo/GO_0048521 GO:0048520 biolink:BiologicalProcess positive regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. go-plus.json upregulation of behavior|stimulation of behavior|up-regulation of behavior|activation of behavior|up regulation of behavior http://purl.obolibrary.org/obo/GO_0048520 CHEBI:87687 biolink:ChemicalSubstance (3S)-3-hydroxyoleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87687 chebi_ph7_3 GO:0048529 biolink:MolecularActivity magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O. EC:1.14.13.81|RHEA:33235 go-plus.json Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity|magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)|Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity http://purl.obolibrary.org/obo/GO_0048529 GO:0048528 biolink:BiologicalProcess post-embryonic root development The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048528 PR:000001887 biolink:Protein melanotransferrin A protein that is a translation product of the human MELTF gene or a 1:1 ortholog thereof. go-plus.json MELTF|membrane-bound transferrin-like protein p97|MTf|MFI2|CD228|MAP97|melanoma-associated antigen p97 http://purl.obolibrary.org/obo/PR_000001887 CHEBI:73030 biolink:ChemicalSubstance (+)-maackiain go-plus.json http://purl.obolibrary.org/obo/CHEBI_73030 chebi_ph7_3 CHEBI:73036 biolink:ChemicalSubstance 4-hydroxy-2-oxoheptanedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73036 chebi_ph7_3 GO:0048530 biolink:BiologicalProcess fruit morphogenesis The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant. go-plus.json http://purl.obolibrary.org/obo/GO_0048530 GO:1903939 biolink:BiologicalProcess regulation of TORC2 signaling Any process that modulates the frequency, rate or extent of TORC2 signaling. go-plus.json regulation of TORC2 signal transduction http://purl.obolibrary.org/obo/GO_1903939 PR:000025848 biolink:Protein type I interferon A protein that consists solely of an Interferon alpha/beta domain (Pfam:PF00143) and which binds to a specific cell surface receptor complex known as the IFN-alpha receptor (IFNAR), a heterodimer of IFNAR1 and IFNAR2 chains. go-plus.json interferon type I|IFN type I http://purl.obolibrary.org/obo/PR_000025848 GO:1903938 biolink:BiologicalProcess cellular response to acrylamide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903938 GO:1903937 biolink:BiologicalProcess response to acrylamide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903937 GO:1903936 biolink:BiologicalProcess cellular response to sodium arsenite Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903936 GO:1903935 biolink:BiologicalProcess response to sodium arsenite Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903935 PR:000025845 biolink:Protein ephrin receptor A protein that consists of an Ephrin receptor ligand binding domain (Pfam:PF01404), two copies of the Fibronectin type III domain (Pfam:PF00041), and a copy of either type of SAM domain (Sterile alpha motif) (Pfam:PF00536 or Pfam:PF07647). go-plus.json http://purl.obolibrary.org/obo/PR_000025845 GO:1903934 biolink:BiologicalProcess positive regulation of DNA primase activity Any process that activates or increases the frequency, rate or extent of DNA primase activity. go-plus.json upregulation of DNA primase activity|activation of DNA primase activity|up-regulation of DNA primase activity|up regulation of DNA primase activity http://purl.obolibrary.org/obo/GO_1903934 GO:1903933 biolink:BiologicalProcess negative regulation of DNA primase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity. go-plus.json downregulation of DNA primase activity|down regulation of DNA primase activity|inhibition of DNA primase activity|down-regulation of DNA primase activity http://purl.obolibrary.org/obo/GO_1903933 GO:0048538 biolink:BiologicalProcess thymus development The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. go-plus.json http://purl.obolibrary.org/obo/GO_0048538 GO:1903932 biolink:BiologicalProcess regulation of DNA primase activity Any process that modulates the frequency, rate or extent of DNA primase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903932 GO:0048537 biolink:BiologicalProcess mucosa-associated lymphoid tissue development The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes. go-plus.json nasopharyngeal-associated lymphoid tissue development|BALT development|bronchial-associated lymphoid tissue development|GALT development|gut-associated lymphoid tissue development|NALT development|mucosal-associated lymphoid tissue development http://purl.obolibrary.org/obo/GO_0048537 GO:1903931 biolink:BiologicalProcess positive regulation of pyrimidine-containing compound salvage Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage. go-plus.json up-regulation of pyrimidine salvage|upregulation of pyrimidine-containing compound salvage|activation of pyrimidine salvage|up-regulation of pyrimidine-containing compound salvage|positive regulation of pyrimidine salvage|activation of pyrimidine-containing compound salvage|up regulation of pyrimidine salvage|upregulation of pyrimidine salvage|up regulation of pyrimidine-containing compound salvage http://purl.obolibrary.org/obo/GO_1903931 GO:0048536 biolink:BiologicalProcess spleen development The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. go-plus.json http://purl.obolibrary.org/obo/GO_0048536 CHEBI:87673 biolink:ChemicalSubstance 2-O-(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87673 chebi_ph7_3 GO:1903930 biolink:BiologicalProcess regulation of pyrimidine-containing compound salvage Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage. go-plus.json regulation of pyrimidine salvage http://purl.obolibrary.org/obo/GO_1903930 GO:0048535 biolink:BiologicalProcess lymph node development The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. go-plus.json lymph gland development http://purl.obolibrary.org/obo/GO_0048535 GO:0048534 biolink:BiologicalProcess hematopoietic or lymphoid organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. go-plus.json hemopoietic or lymphoid organ development|haemopoietic or lymphoid organ development|haematopoietic or lymphoid organ development http://purl.obolibrary.org/obo/GO_0048534 GO:0048533 biolink:BiologicalProcess sporocyte differentiation The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores. go-plus.json sporocyte development|sporocyte morphogenesis http://purl.obolibrary.org/obo/GO_0048533 GO:0048532 biolink:BiologicalProcess anatomical structure arrangement The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. go-plus.json organization of an anatomical structure|anatomical structure structural organization|structural organization|anatomical structure organization http://purl.obolibrary.org/obo/GO_0048532 CHEBI:87677 biolink:ChemicalSubstance (25R)-3beta-hydroxycholest-5-en-7-one-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_87677 chebi_ph7_3 GO:0048531 biolink:MolecularActivity beta-1,3-galactosyltransferase activity Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0048531 CHEBI:87678 biolink:ChemicalSubstance (25R)-3beta-hydroxycholest-5-en-7-one-26-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87678 chebi_ph7_3 GO:0048539 biolink:BiologicalProcess bone marrow development The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048539 GO:0048541 biolink:BiologicalProcess Peyer's patch development The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. go-plus.json GALT development|gut-associated lymphoid tissue development http://purl.obolibrary.org/obo/GO_0048541 GO:0048540 biolink:BiologicalProcess bursa of Fabricius development The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0048540 GO:1903949 biolink:BiologicalProcess positive regulation of atrial cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential. go-plus.json up-regulation of atrial cardiac muscle cell action potential|upregulation of atrial cardiac muscle cell action potential|up regulation of atrial cardiac muscle cell action potential|activation of atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903949 GO:1903948 biolink:BiologicalProcess negative regulation of atrial cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential. go-plus.json inhibition of atrial cardiac muscle cell action potential|down regulation of atrial cardiac muscle cell action potential|downregulation of atrial cardiac muscle cell action potential|down-regulation of atrial cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903948 GO:1903947 biolink:BiologicalProcess positive regulation of ventricular cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential. go-plus.json up-regulation of ventricular cardiac muscle cell action potential|activation of ventricular cardiac muscle cell action potential|up regulation of ventricular cardiac muscle cell action potential|upregulation of ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903947 GO:1903946 biolink:BiologicalProcess negative regulation of ventricular cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential. go-plus.json down-regulation of ventricular cardiac muscle cell action potential|downregulation of ventricular cardiac muscle cell action potential|down regulation of ventricular cardiac muscle cell action potential|inhibition of ventricular cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903946 GO:1903945 biolink:BiologicalProcess positive regulation of hepatocyte apoptotic process Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process. go-plus.json up-regulation of hepatocyte apoptosis|up-regulation of hepatocyte apoptotic process|activation of hepatocyte apoptosis|activation of hepatocyte apoptotic process|positive regulation of hepatocyte apoptosis|up regulation of hepatocyte apoptosis|up regulation of hepatocyte apoptotic process|upregulation of hepatocyte apoptosis|upregulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1903945 GO:1903944 biolink:BiologicalProcess negative regulation of hepatocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process. go-plus.json down-regulation of hepatocyte apoptosis|negative regulation of hepatocyte apoptosis|down-regulation of hepatocyte apoptotic process|downregulation of hepatocyte apoptosis|down regulation of hepatocyte apoptosis|downregulation of hepatocyte apoptotic process|down regulation of hepatocyte apoptotic process|inhibition of hepatocyte apoptosis|inhibition of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1903944 GO:0048549 biolink:BiologicalProcess positive regulation of pinocytosis Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. go-plus.json up regulation of pinocytosis|activation of pinocytosis|stimulation of pinocytosis|up-regulation of pinocytosis|upregulation of pinocytosis http://purl.obolibrary.org/obo/GO_0048549 GO:0048548 biolink:BiologicalProcess regulation of pinocytosis Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0048548 GO:1903943 biolink:BiologicalProcess regulation of hepatocyte apoptotic process Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process. go-plus.json regulation of hepatocyte apoptosis http://purl.obolibrary.org/obo/GO_1903943 GO:1903942 biolink:BiologicalProcess positive regulation of respiratory gaseous exchange Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. go-plus.json upregulation of respiratory gaseous exchange|up-regulation of respiratory gaseous exchange|activation of respiratory gaseous exchange|up regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_1903942 GO:0048547 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048547 GO:1903941 biolink:BiologicalProcess negative regulation of respiratory gaseous exchange Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. go-plus.json downregulation of respiratory gaseous exchange|down regulation of respiratory gaseous exchange|inhibition of respiratory gaseous exchange|down-regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_1903941 GO:0048546 biolink:BiologicalProcess digestive tract morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. go-plus.json gastrointestinal tract morphogenesis|gut morphogenesis|digestive tube morphogenesis|intestinal morphogenesis|alimentary canal morphogenesis http://purl.obolibrary.org/obo/GO_0048546 GO:1903940 biolink:BiologicalProcess negative regulation of TORC2 signaling Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling. go-plus.json downregulation of TORC2 signaling|down regulation of TORC2 signal transduction|downregulation of TORC2 signal transduction|down-regulation of TORC2 signaling|negative regulation of TORC2 signal transduction|down-regulation of TORC2 signal transduction|inhibition of TORC2 signaling|inhibition of TORC2 signal transduction|down regulation of TORC2 signaling http://purl.obolibrary.org/obo/GO_1903940 GO:0048545 biolink:BiologicalProcess response to steroid hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. go-plus.json response to steroid hormone stimulus http://purl.obolibrary.org/obo/GO_0048545 GO:0048544 biolink:BiologicalProcess recognition of pollen The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species. go-plus.json pollen recognition|self incompatibility|recognition or rejection of self pollen http://purl.obolibrary.org/obo/GO_0048544 GO:0048543 biolink:BiologicalProcess phytochrome chromophore biosynthetic process The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form. go-plus.json phytochrome chromophore anabolism|phytochrome chromophore biosynthesis|phytochrome chromophore synthesis|phytochrome chromophore formation http://purl.obolibrary.org/obo/GO_0048543 GO:0048542 biolink:BiologicalProcess lymph gland development The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. go-plus.json haematopoietic organ development|hemopoietic organ development|hematopoietic organ development|haemopoietic organ development http://purl.obolibrary.org/obo/GO_0048542 CHEBI:73054 biolink:ChemicalSubstance O-dodecanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73054 chebi_ph7_3 GO:0048552 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048552 GO:0048551 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048551 GO:0048550 biolink:BiologicalProcess negative regulation of pinocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. go-plus.json down regulation of pinocytosis|downregulation of pinocytosis|down-regulation of pinocytosis|inhibition of pinocytosis http://purl.obolibrary.org/obo/GO_0048550 PO:0025450 biolink:OntologyClass primary xylem vessel A xylem vessel (PO:0025417) that is part of a primary xylem tissue (PO:0005849). go-plus.json vaso del xilema primario (Spanish, exact)|一次木質部導管 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025450 GO:1903959 biolink:BiologicalProcess regulation of anion transmembrane transport Any process that modulates the frequency, rate or extent of anion transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1903959 GO:1903958 biolink:CellularComponent nitric-oxide synthase complex A protein complex which is capable of nitric-oxide synthase activity. go-plus.json iNOS-S100A8/A9 complex http://purl.obolibrary.org/obo/GO_1903958 GO:1903957 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903957 CHEBI:87691 biolink:ChemicalSubstance tetradecanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_87691 chebi_ph7_3 GO:1903956 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903956 GO:1903955 biolink:BiologicalProcess positive regulation of protein targeting to mitochondrion Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion. go-plus.json up regulation of protein-mitochondrial targeting|activation of protein-mitochondrial targeting|positive regulation of protein-mitochondrial targeting|up-regulation of protein import into mitochondrion|up-regulation of mitochondrial protein import|upregulation of mitochondrial translocation|up-regulation of protein targeting to mitochondria|upregulation of protein targeting to mitochondrion|activation of mitochondrial protein import|upregulation of protein import into mitochondrion|up-regulation of protein-mitochondrial targeting|positive regulation of mitochondrial protein import|upregulation of protein targeting to mitochondria|up regulation of mitochondrial translocation|up-regulation of protein targeting to mitochondrion|activation of protein targeting to mitochondrion|up regulation of mitochondrial protein import|positive regulation of mitochondrial translocation|up regulation of protein import into mitochondrion|activation of mitochondrial translocation|upregulation of protein-mitochondrial targeting|activation of protein import into mitochondrion|positive regulation of protein import into mitochondrion|up regulation of protein targeting to mitochondria|activation of protein targeting to mitochondria|positive regulation of protein targeting to mitochondria|upregulation of mitochondrial protein import|up-regulation of mitochondrial translocation|up regulation of protein targeting to mitochondrion http://purl.obolibrary.org/obo/GO_1903955 GO:1903954 biolink:BiologicalProcess positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. go-plus.json up-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|positive regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|up-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization http://purl.obolibrary.org/obo/GO_1903954 GO:0048559 biolink:BiologicalProcess establishment of floral organ orientation The process that determines the orientation of the floral organs with reference to the central axis of the flower. go-plus.json http://purl.obolibrary.org/obo/GO_0048559 GO:1903953 biolink:BiologicalProcess negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. go-plus.json inhibition of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|negative regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|inhibition of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_1903953 GO:0048558 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048558 CHEBI:87695 biolink:ChemicalSubstance 3-oxooleoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87695 chebi_ph7_3 GO:0048557 biolink:BiologicalProcess embryonic digestive tract morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed. go-plus.json embryonic gut morphogenesis http://purl.obolibrary.org/obo/GO_0048557 GO:1903952 biolink:BiologicalProcess regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. go-plus.json regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization http://purl.obolibrary.org/obo/GO_1903952 GO:0048556 biolink:CellularComponent microsporocyte nucleus The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte. go-plus.json pollen mother cell nucleus|microspore mother cell nucleus http://purl.obolibrary.org/obo/GO_0048556 GO:1903951 biolink:BiologicalProcess positive regulation of AV node cell action potential Any process that activates or increases the frequency, rate or extent of AV node cell action potential. go-plus.json positive regulation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cell action potential|up regulation of atrioventricular node cardiac muscle cell action potential|positive regulation of AV node cardiac muscle cell action potential|up regulation of AV node cardiac muscle cell action potential|upregulation of AV node cell action potential|upregulation of atrioventricular node cardiac muscle cell action potential|upregulation of AV node cardiac muscle cell action potential|up regulation of AV node cell action potential|activation of AV node cell action potential|up-regulation of atrioventricular node cardiac muscle cell action potential|activation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cardiac muscle cell action potential|activation of AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903951 GO:1903950 biolink:BiologicalProcess negative regulation of AV node cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential. go-plus.json inhibition of AV node cell action potential|negative regulation of AV node cardiac muscle cell action potential|down-regulation of AV node cardiac muscle cell action potential|downregulation of atrioventricular node cardiac muscle cell action potential|down regulation of atrioventricular node cardiac muscle cell action potential|downregulation of AV node cardiac muscle cell action potential|inhibition of atrioventricular node cardiac muscle cell action potential|down regulation of AV node cell action potential|down regulation of AV node cardiac muscle cell action potential|inhibition of AV node cardiac muscle cell action potential|downregulation of AV node cell action potential|down-regulation of AV node cell action potential|negative regulation of atrioventricular node cardiac muscle cell action potential|down-regulation of atrioventricular node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1903950 GO:0048555 biolink:CellularComponent generative cell nucleus The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells. go-plus.json sperm cell nucleus|male germ cell nucleus http://purl.obolibrary.org/obo/GO_0048555 GO:0048554 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048554 GO:0048553 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048553 CHEBI:87698 biolink:ChemicalSubstance (7Z)-hexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87698 chebi_ph7_3 CL:1001451 biolink:Cell sensory neuron of dorsal root ganglion A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord. go-plus.json proprioceptive neuron http://purl.obolibrary.org/obo/CL_1001451 CHEBI:73061 biolink:ChemicalSubstance O-tetradecanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73061 chebi_ph7_3 PO:0025448 biolink:OntologyClass primary xylem vessel member A xylem vessel member (PO:0002003) that is part of a primary xylem tissue (PO:0005849). go-plus.json primary xylem vessel element (exact)|elemento vaso del xilema primario (Spanish, exact)|一次木質部導管状要素 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025448 CHEBI:73067 biolink:ChemicalSubstance O-palmitoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73067 chebi_ph7_3 GO:0048563 biolink:BiologicalProcess post-embryonic animal organ morphogenesis Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json http://purl.obolibrary.org/obo/GO_0048563 CHEBI:143285 biolink:ChemicalSubstance L-propargylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143285 chebi_ph7_3 GO:0048562 biolink:BiologicalProcess embryonic organ morphogenesis Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json http://purl.obolibrary.org/obo/GO_0048562 GO:0048561 biolink:BiologicalProcess establishment of animal organ orientation The process that determines the orientation of an animal organ or tissue with reference to an axis. go-plus.json http://purl.obolibrary.org/obo/GO_0048561 GO:0048560 biolink:BiologicalProcess establishment of anatomical structure orientation The process that determines the orientation of an anatomical structure with reference to an axis. go-plus.json http://purl.obolibrary.org/obo/GO_0048560 GO:1903969 biolink:BiologicalProcess regulation of response to macrophage colony-stimulating factor Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor. go-plus.json regulation of response to macrophage colony-stimulating factor|regulation of response to M-CSF|regulation of response to macrophage colony-stimulating factor stimulus http://purl.obolibrary.org/obo/GO_1903969 GO:1903968 biolink:BiologicalProcess cellular response to micafungin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903968 GO:1903967 biolink:BiologicalProcess response to micafungin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903967 GO:1903966 biolink:BiologicalProcess monounsaturated fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid. go-plus.json monounsaturated fatty acid biosynthesis|monounsaturated fatty acid anabolism|monounsaturated fatty acid synthesis|monounsaturated fatty acid formation http://purl.obolibrary.org/obo/GO_1903966 GO:1903965 biolink:BiologicalProcess monounsaturated fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid. go-plus.json monounsaturated fatty acid catabolism|monounsaturated fatty acid breakdown|monounsaturated fatty acid degradation http://purl.obolibrary.org/obo/GO_1903965 GO:0048569 biolink:BiologicalProcess post-embryonic animal organ development Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json post-embryonic animal organogenesis http://purl.obolibrary.org/obo/GO_0048569 GO:1903964 biolink:BiologicalProcess monounsaturated fatty acid metabolic process The chemical reactions and pathways involving monounsaturated fatty acid. go-plus.json monounsaturated fatty acid metabolism http://purl.obolibrary.org/obo/GO_1903964 GO:1903963 biolink:BiologicalProcess arachidonate transport The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json arachidonic acid transport http://purl.obolibrary.org/obo/GO_1903963 GO:0048568 biolink:BiologicalProcess embryonic organ development Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. go-plus.json embryonic organogenesis http://purl.obolibrary.org/obo/GO_0048568 GO:1903962 biolink:MolecularActivity arachidonate transmembrane transporter activity Enables the transfer of arachidonate from one side of a membrane to the other. go-plus.json arachidonate transporter activity|arachidonic acid transporter activity http://purl.obolibrary.org/obo/GO_1903962 GO:0048567 biolink:BiologicalProcess ectodermal digestive tract morphogenesis The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm. go-plus.json ectodermal gut morphogenesis http://purl.obolibrary.org/obo/GO_0048567 GO:0048566 biolink:BiologicalProcess embryonic digestive tract development The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus. go-plus.json embryonic digestive tract development http://purl.obolibrary.org/obo/GO_0048566 GO:1903961 biolink:BiologicalProcess positive regulation of anion transmembrane transport Any process that activates or increases the frequency, rate or extent of anion transmembrane transport. go-plus.json up regulation of anion transmembrane transport|activation of anion transmembrane transport|up-regulation of anion transmembrane transport|upregulation of anion transmembrane transport http://purl.obolibrary.org/obo/GO_1903961 GO:1903960 biolink:BiologicalProcess negative regulation of anion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport. go-plus.json down-regulation of anion transmembrane transport|inhibition of anion transmembrane transport|down regulation of anion transmembrane transport|downregulation of anion transmembrane transport http://purl.obolibrary.org/obo/GO_1903960 GO:0048565 biolink:BiologicalProcess digestive tract development The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. go-plus.json gut development|intestine development|intestinal development http://purl.obolibrary.org/obo/GO_0048565 GO:0048564 biolink:BiologicalProcess photosystem I assembly The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0048564 CHEBI:73078 biolink:ChemicalSubstance 3''-deamino-3''-hydroxykanamycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_73078 PO:0025433 biolink:OntologyClass root anlagen A portion of meristem tissue (PO:0009013) that is committed to the development of a root primordium (PO:0005029). go-plus.json precursor de raí (Spanish, exact)|根原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025433 PO:0025432 biolink:OntologyClass cotyledon anlagen A phyllome anlagen (PO:0025430) that will give rise to a cotyledon primordium (PO:0000015) and is part of a peripheral zone (PO:000225) of an embryo shoot apical meristem (PO:0006362). go-plus.json precursor de cotiledón (Spanish, exact)|子葉原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025432 CHEBI:73079 biolink:ChemicalSubstance kanamycin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_73079 GO:0048574 biolink:BiologicalProcess long-day photoperiodism, flowering A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length. go-plus.json long-day photoperiodic control of flowering|long-day photoperiodic control of flowering time|response to long-day, flowering|response to short-night, flowering|long-day photoperiodic control of inflorescence development|short-night photoperiodism, flowering http://purl.obolibrary.org/obo/GO_0048574 PO:0025431 biolink:OntologyClass vascular leaf anlagen A phyllome anlagen (PO:0025430) that will give rise to a vascular leaf primordium (PO:0000017) and is part of a peripheral zone (PO:0000225) of a shoot apical meristem (PO:0020148). go-plus.json leaf meristem (broad)|維管束系葉原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025431 CHEBI:143274 biolink:ChemicalSubstance indole-3-butyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_143274 chebi_ph7_3 GO:0048573 biolink:BiologicalProcess photoperiodism, flowering A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species. go-plus.json response to photoperiod, flowering|response to day length, flowering|response to night length, flowering|photoperiodic control of inflorescence development|photoperiodic control of flowering time http://purl.obolibrary.org/obo/GO_0048573 PO:0025430 biolink:OntologyClass phyllome anlagen A portion of meristem tissue (PO:0009013) that is part of a peripheral zone (PO:0000225) of a shoot apical meristem (PO:0020148) and will give rise to a phyllome primordium (PO:0025128). go-plus.json phyllome meristem (broad)|フィロム原基 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025430 GO:0048572 biolink:BiologicalProcess short-day photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length. go-plus.json response to short-day|response to short-day photoperiod|response to long-night|long-night photoperiodism http://purl.obolibrary.org/obo/GO_0048572 GO:0048571 biolink:BiologicalProcess long-day photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length. go-plus.json response to short-night|response to long-day photoperiod|response to long-day|short-night photoperiodism http://purl.obolibrary.org/obo/GO_0048571 GO:0048570 biolink:BiologicalProcess notochord morphogenesis The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. go-plus.json http://purl.obolibrary.org/obo/GO_0048570 GO:1903979 biolink:BiologicalProcess negative regulation of microglial cell activation Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation. go-plus.json downregulation of microglial cell activation|down regulation of microglial cell activation|inhibition of microglial cell activation|down-regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_1903979 GO:1903978 biolink:BiologicalProcess regulation of microglial cell activation Any process that modulates the frequency, rate or extent of microglial cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_1903978 GO:1903977 biolink:BiologicalProcess positive regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of glial cell migration. go-plus.json up regulation of glial cell migration|activation of glia cell migration|positive regulation of glia cell migration|upregulation of glial cell migration|up-regulation of glia cell migration|up-regulation of glial cell migration|upregulation of glia cell migration|activation of glial cell migration|up regulation of glia cell migration http://purl.obolibrary.org/obo/GO_1903977 GO:1903976 biolink:BiologicalProcess negative regulation of glial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. go-plus.json downregulation of glial cell migration|negative regulation of glia cell migration|down-regulation of glia cell migration|down regulation of glial cell migration|inhibition of glial cell migration|inhibition of glia cell migration|down regulation of glia cell migration|down-regulation of glial cell migration|downregulation of glia cell migration http://purl.obolibrary.org/obo/GO_1903976 GO:1903975 biolink:BiologicalProcess regulation of glial cell migration Any process that modulates the frequency, rate or extent of glial cell migration. go-plus.json regulation of glia cell migration http://purl.obolibrary.org/obo/GO_1903975 GO:1903974 biolink:BiologicalProcess positive regulation of cellular response to macrophage colony-stimulating factor stimulus Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus. go-plus.json up-regulation of cellular response to macrophage colony-stimulating factor stimulus|activation of cellular response to macrophage colony-stimulating factor stimulus|upregulation of cellular response to macrophage colony-stimulating factor|upregulation of cellular response to M-CSF stimulus|up regulation of cellular response to macrophage colony-stimulating factor|positive regulation of cellular response to macrophage colony-stimulating factor|up regulation of cellular response to macrophage colony-stimulating factor stimulus|activation of cellular response to macrophage colony-stimulating factor|up regulation of cellular response to M-CSF stimulus|positive regulation of cellular response to M-CSF stimulus|activation of cellular response to M-CSF stimulus|upregulation of cellular response to macrophage colony-stimulating factor stimulus|up-regulation of cellular response to macrophage colony-stimulating factor|up-regulation of cellular response to M-CSF stimulus http://purl.obolibrary.org/obo/GO_1903974 GO:0048579 biolink:BiologicalProcess negative regulation of long-day photoperiodism, flowering Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. go-plus.json downregulation of long-day photoperiodism, flowering|down regulation of long-day photoperiodism, flowering|inhibition of long-day photoperiodism, flowering|down-regulation of long-day photoperiodism, flowering http://purl.obolibrary.org/obo/GO_0048579 GO:1903973 biolink:BiologicalProcess negative regulation of cellular response to macrophage colony-stimulating factor stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus. go-plus.json down regulation of cellular response to macrophage colony-stimulating factor|down-regulation of cellular response to macrophage colony-stimulating factor stimulus|downregulation of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to M-CSF stimulus|downregulation of cellular response to M-CSF stimulus|downregulation of cellular response to macrophage colony-stimulating factor stimulus|down-regulation of cellular response to macrophage colony-stimulating factor|negative regulation of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to macrophage colony-stimulating factor stimulus|inhibition of cellular response to macrophage colony-stimulating factor stimulus|negative regulation of cellular response to M-CSF stimulus|down-regulation of cellular response to M-CSF stimulus|inhibition of cellular response to macrophage colony-stimulating factor|inhibition of cellular response to M-CSF stimulus http://purl.obolibrary.org/obo/GO_1903973 GO:0048578 biolink:BiologicalProcess positive regulation of long-day photoperiodism, flowering Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. go-plus.json up regulation of long-day photoperiodism, flowering|upregulation of long-day photoperiodism, flowering|stimulation of long-day photoperiodism, flowering|up-regulation of long-day photoperiodism, flowering|activation of long-day photoperiodism, flowering http://purl.obolibrary.org/obo/GO_0048578 GO:0048577 biolink:BiologicalProcess negative regulation of short-day photoperiodism, flowering Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. go-plus.json inhibition of short-day photoperiodism, flowering|down regulation of short-day photoperiodism, flowering|downregulation of short-day photoperiodism, flowering|down-regulation of short-day photoperiodism, flowering http://purl.obolibrary.org/obo/GO_0048577 GO:1903972 biolink:BiologicalProcess regulation of cellular response to macrophage colony-stimulating factor stimulus Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus. go-plus.json regulation of cellular response to macrophage colony-stimulating factor|regulation of cellular response to M-CSF stimulus http://purl.obolibrary.org/obo/GO_1903972 GO:1903971 biolink:BiologicalProcess positive regulation of response to macrophage colony-stimulating factor Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor. go-plus.json up regulation of response to M-CSF|activation of response to M-CSF|positive regulation of response to M-CSF|up-regulation of response to macrophage colony-stimulating factor|activation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor stimulus|activation of response to macrophage colony-stimulating factor stimulus|positive regulation of response to macrophage colony-stimulating factor stimulus|up-regulation of response to M-CSF|positive regulation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor|up-regulation of response to macrophage colony-stimulating factor stimulus|upregulation of response to M-CSF|upregulation of response to macrophage colony-stimulating factor|upregulation of response to macrophage colony-stimulating factor stimulus http://purl.obolibrary.org/obo/GO_1903971 GO:0048576 biolink:BiologicalProcess positive regulation of short-day photoperiodism, flowering Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. go-plus.json up-regulation of short-day photoperiodism, flowering|upregulation of short-day photoperiodism, flowering|up regulation of short-day photoperiodism, flowering|activation of short-day photoperiodism, flowering|stimulation of short-day photoperiodism, flowering http://purl.obolibrary.org/obo/GO_0048576 GO:0048575 biolink:BiologicalProcess short-day photoperiodism, flowering A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length. go-plus.json short-day photoperiodic control of flowering|response to long-night, flowering|short-day photoperiodic control of flowering time|short-day photoperiodic control of inflorescence development|response to short-day, flowering|long-night photoperiodism, flowering http://purl.obolibrary.org/obo/GO_0048575 GO:1903970 biolink:BiologicalProcess negative regulation of response to macrophage colony-stimulating factor Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor. go-plus.json downregulation of response to macrophage colony-stimulating factor stimulus|down-regulation of response to M-CSF|negative regulation of response to M-CSF|negative regulation of response to macrophage colony-stimulating factor|down-regulation of response to macrophage colony-stimulating factor|down-regulation of response to macrophage colony-stimulating factor stimulus|negative regulation of response to macrophage colony-stimulating factor stimulus|inhibition of response to M-CSF|downregulation of response to macrophage colony-stimulating factor|inhibition of response to macrophage colony-stimulating factor stimulus|down regulation of response to macrophage colony-stimulating factor|inhibition of response to macrophage colony-stimulating factor|down regulation of response to M-CSF|downregulation of response to M-CSF|down regulation of response to macrophage colony-stimulating factor stimulus http://purl.obolibrary.org/obo/GO_1903970 GO:1903980 biolink:BiologicalProcess positive regulation of microglial cell activation Any process that activates or increases the frequency, rate or extent of microglial cell activation. go-plus.json up-regulation of microglial cell activation|activation of microglial cell activation|up regulation of microglial cell activation|upregulation of microglial cell activation http://purl.obolibrary.org/obo/GO_1903980 CL:1001474 biolink:Cell medium spiny neuron The inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus. go-plus.json medium-sized densely spiny neuron|striatal medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 CHEBI:73081 biolink:ChemicalSubstance O-(15-carboxypentadecanoyl)carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73081 CHEBI:73080 biolink:ChemicalSubstance hemiaminal go-plus.json http://purl.obolibrary.org/obo/CHEBI_73080 CHEBI:73083 biolink:ChemicalSubstance (7,8-dihydropterin-6-yl)methyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73083 CHEBI:73084 biolink:ChemicalSubstance N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73084 CHEBI:73087 biolink:ChemicalSubstance dihydrourocanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73087 CHEBI:73089 biolink:ChemicalSubstance 4-hydroxy-2-oxoheptanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73089 CHEBI:24002 biolink:ChemicalSubstance ethylene releasers go-plus.json http://purl.obolibrary.org/obo/CHEBI_24002 UBERON:0001668 biolink:AnatomicalEntity cerebellar vein A vein that drains the cerebellum. go-plus.json epencephalon-1 vein|vein of cerebellum|cerebellum vein|vein of epencephalon-1 http://purl.obolibrary.org/obo/UBERON_0001668 GO:0000721 biolink:MolecularActivity (R,R)-butanediol dehydrogenase activity Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+). RHEA:24340|EC:1.1.1.4|MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN go-plus.json D-1-amino-2-propanol:NAD(2) oxidoreductase activity|aminopropanol oxidoreductase activity|(R)-2,3-butanediol dehydrogenase activity|D-1-amino-2-propanol dehydrogenase activity|D-butanediol dehydrogenase activity|D-aminopropanol dehydrogenase activity|(R)-diacetyl reductase activity|diacetyl (acetoin) reductase activity|butylene glycol dehydrogenase activity|D-(-)-butanediol dehydrogenase activity|2,3-butanediol dehydrogenase activity|1-amino-2-propanol oxidoreductase activity|1-amino-2-propanol dehydrogenase activity|butyleneglycol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0000721 GO:0000720 biolink:BiologicalProcess pyrimidine dimer repair by nucleotide-excision repair The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. go-plus.json http://purl.obolibrary.org/obo/GO_0000720 NCBITaxon:2759 biolink:OrganismalEntity Eukaryota go-plus.json eukaryotes|eukaryotes|Eucaryotae|Eukaryotae|Eukarya|eucaryotes|Eucarya http://purl.obolibrary.org/obo/NCBITaxon_2759 CHEBI:38646 biolink:ChemicalSubstance O-beta-D-glucosylzeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38646 CHEBI:38645 biolink:ChemicalSubstance N-glycosylzeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38645 CHEBI:38644 biolink:ChemicalSubstance O-beta-D-glucosylzeatins go-plus.json http://purl.obolibrary.org/obo/CHEBI_38644 CHEBI:38643 biolink:ChemicalSubstance 6-isopentenylaminopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38643 UBERON:0001675 biolink:AnatomicalEntity trigeminal ganglion The cranial ganglion that is associated with and extends fibers into the trigeminal nerve. go-plus.json trigeminal V ganglion|fused trigeminal ganglion|trigeminus ganglion|trigeminal ganglia|Gasserian ganglion|Gasserian ganglia|ganglion trigeminale|ganglion of trigeminal complex|Gasser's ganglion|fifth ganglion|ganglion of trigeminal nerve|gV|ganglion semilunare|semilunar ganglion|5th ganglion http://purl.obolibrary.org/obo/UBERON_0001675 GO:0000725 biolink:BiologicalProcess recombinational repair A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region. Wikipedia:Recombinational_repair go-plus.json http://purl.obolibrary.org/obo/GO_0000725 GO:0000724 biolink:BiologicalProcess double-strand break repair via homologous recombination The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. go-plus.json homologous recombinational repair|homology-directed repair|HDR|HRR|Rad51-dependent recombinational repair|Rhp51-dependent recombinational repair http://purl.obolibrary.org/obo/GO_0000724 UBERON:0001677 biolink:AnatomicalEntity sphenoid bone An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended. go-plus.json os sphenoidum|os sphenoidale|sphenoidal bone|sphenoid complex|sphenoid|butterfly bone|os sphenoidale http://purl.obolibrary.org/obo/UBERON_0001677 GO:0000723 biolink:BiologicalProcess telomere maintenance Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences. go-plus.json regulation of telomere length http://purl.obolibrary.org/obo/GO_0000723 CHEBI:63618 biolink:ChemicalSubstance pravastatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63618 GO:0000722 biolink:BiologicalProcess telomere maintenance via recombination Any recombinational process that contributes to the maintenance of proper telomeric length. go-plus.json telomerase-independent telomere maintenance http://purl.obolibrary.org/obo/GO_0000722 UBERON:0001676 biolink:AnatomicalEntity occipital bone the bone at the lower, posterior part of the skull go-plus.json occipital complex|os occipitale|occipital squama http://purl.obolibrary.org/obo/UBERON_0001676 GO:0000729 biolink:BiologicalProcess DNA double-strand break processing The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang. go-plus.json http://purl.obolibrary.org/obo/GO_0000729 GO:0000728 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000728 GO:0000727 biolink:BiologicalProcess double-strand break repair via break-induced replication The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000727 GO:0000726 biolink:BiologicalProcess obsolete non-recombinational repair OBSOLETE. A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous DNA region. go-plus.json http://purl.obolibrary.org/obo/GO_0000726 GO:0000732 biolink:BiologicalProcess strand displacement The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. go-plus.json displacement loop dissociation|D-loop dissociation|displacement loop processing|D-loop processing http://purl.obolibrary.org/obo/GO_0000732 GO:0000731 biolink:BiologicalProcess DNA synthesis involved in DNA repair Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template. go-plus.json DNA repair synthesis|mitotic DNA repair synthesis|DNA synthesis during DNA repair http://purl.obolibrary.org/obo/GO_0000731 GO:0000730 biolink:BiologicalProcess DNA recombinase assembly The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA. go-plus.json Rad51 nucleoprotein filament formation http://purl.obolibrary.org/obo/GO_0000730 CHEBI:24018 biolink:ChemicalSubstance farnesyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24018 CHEBI:133901 biolink:ChemicalSubstance 3-aminobutyryl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133901 chebi_ph7_3 CHEBI:133900 biolink:ChemicalSubstance 14(R),15(S)-DiHPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133900 chebi_ph7_3 CHEBI:133903 biolink:ChemicalSubstance 8(S),15(S)-DiHETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133903 chebi_ph7_3 CHEBI:133902 biolink:ChemicalSubstance dUMP residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133902 chebi_ph7_3 CHEBI:24012 biolink:ChemicalSubstance farnesal go-plus.json http://purl.obolibrary.org/obo/CHEBI_24012 chebi_ph7_3 CHEBI:63624 biolink:ChemicalSubstance telbivudine go-plus.json http://purl.obolibrary.org/obo/CHEBI_63624 chebi_ph7_3 CHEBI:38656 biolink:ChemicalSubstance organochlorine pesticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38656 CHEBI:38655 biolink:ChemicalSubstance (S)-2-methylbutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38655 GO:0000736 biolink:BiologicalProcess double-strand break repair via single-strand annealing, removal of nonhomologous ends During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. go-plus.json http://purl.obolibrary.org/obo/GO_0000736 UBERON:0001663 biolink:AnatomicalEntity cerebral vein The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]. go-plus.json venae cerebri|venae encephali http://purl.obolibrary.org/obo/UBERON_0001663 GO:0000735 biolink:BiologicalProcess removal of nonhomologous ends The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. go-plus.json http://purl.obolibrary.org/obo/GO_0000735 GO:0000734 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000734 GO:0000733 biolink:BiologicalProcess obsolete DNA strand renaturation OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000733 CHEBI:38653 biolink:ChemicalSubstance methylbutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38653 GO:0000739 biolink:MolecularActivity obsolete DNA strand annealing activity OBSOLETE. Facilitates the base-pairing of complementary single-stranded DNA. go-plus.json DNA strand annealing activity http://purl.obolibrary.org/obo/GO_0000739 GO:0000738 biolink:BiologicalProcess DNA catabolic process, exonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides. go-plus.json exonucleolytic degradation of DNA|DNA degradation, exonucleolytic|DNA breakdown, exonucleolytic http://purl.obolibrary.org/obo/GO_0000738 GO:0000737 biolink:BiologicalProcess DNA catabolic process, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides. go-plus.json endonucleolytic DNA catabolism|DNA degradation, endonucleolytic|endonucleolytic degradation of DNA|DNA breakdown, endonucleolytic http://purl.obolibrary.org/obo/GO_0000737 UBERON:0001649 biolink:AnatomicalEntity glossopharyngeal nerve Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult). go-plus.json nervus glossopharyngeus [ix]|glossopharyngeal IX nerve|CN-IX|9n|ninth cranial nerve|glossopharyngeal nerve tree|cranial nerve IX|nervus glossopharyngeus|glossopharyngeal IX|nervus glossopharyngeus|nerve IX|glossopharyngeal nerve [IX] http://purl.obolibrary.org/obo/UBERON_0001649 UBERON:0001646 biolink:AnatomicalEntity abducens nerve Cranial nerve that runs to the eye muscles. go-plus.json nervus abducens|abducens nerve tree|sixth cranial nerve|lateral rectus nerve|CN-VI|nervus abducens [VI]|6n|cranial nerve VI|abducens nerve [VI]|abducent nerve [VI]|abducens nerve/root|abducens VI nerve|nerve VI|nervus abducens|abducent nerve|abducents VI nerve http://purl.obolibrary.org/obo/UBERON_0001646 UBERON:0001645 biolink:AnatomicalEntity trigeminal nerve Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw). go-plus.json fifth cranial nerve|trigeminal v nerve|cranial nerve V|nervus trigeminus [v]|CN-V|5n|nervus trigeminus|trigeminal V|nervus trigeminus|trigeminus|trigeminal nerve [V]|trigeminal nerve tree|nerve V http://purl.obolibrary.org/obo/UBERON_0001645 UBERON:0001648 biolink:AnatomicalEntity vestibulocochlear nerve Cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. go-plus.json eighth cranial nerve|vestibulocochlear nerve [VIII]|acoustic VIII nerve|CN-VIII|vestibulocochlear VIII nerve|nervus statoacusticus|cranial nerve VIII|cochlear-vestibular nerve|acoustic nerve|8n|vestibulocochlear nerve tree|acoustic nerve (Crosby)|VIIIth cranial nerve|nervus vestibulocochlearis|nervus octavus|octaval nerve|statoacoustic nerve|nervus vestibulocochlearis [viii]|cochleovestibular nerve|stato-acoustic nerve|VIII nerve http://purl.obolibrary.org/obo/UBERON_0001648 UBERON:0001647 biolink:AnatomicalEntity facial nerve Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches). go-plus.json nerve VII|nervus facialis|facial nerve [VII]|facial nerve/root|cranial nerve VII|nerve of face|CN-VII|branchiomeric cranial nerve|7n|facial VII nerve|facial nerve or its root|facial nerve tree|face nerve|seventh cranial nerve|facial VII|nervus facialis [vii]|nervus facialis http://purl.obolibrary.org/obo/UBERON_0001647 CL:1001569 biolink:Cell hippocampal interneuron An interneuron of the hippocampus. go-plus.json http://purl.obolibrary.org/obo/CL_1001569 CL:1001568 biolink:Cell pulmonary artery endothelial cell go-plus.json PAEC cell http://purl.obolibrary.org/obo/CL_1001568 CL:1001567 biolink:Cell lung endothelial cell go-plus.json pulmonary vessel endothelial cell|endothelial cell of lung http://purl.obolibrary.org/obo/CL_1001567 CHEBI:87602 biolink:ChemicalSubstance 4-hydroxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_87602 chebi_ph7_3 CHEBI:38623 biolink:ChemicalSubstance EC 1.4.3.4 (monoamine oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38623 GO:0000709 biolink:BiologicalProcess meiotic joint molecule formation The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000709 GO:0000708 biolink:BiologicalProcess meiotic strand invasion The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis. go-plus.json meiotic displacement loop biosynthesis|meiotic displacement loop formation|meiotic D-loop biosynthesis|meiotic D-loop formation http://purl.obolibrary.org/obo/GO_0000708 CHEBI:87606 biolink:ChemicalSubstance N-icosanoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87606 CHEBI:87605 biolink:ChemicalSubstance 6alpha-hydroxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_87605 chebi_ph7_3 UBERON:0001653 biolink:AnatomicalEntity facial vein The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. go-plus.json vena facialis anterior|anterior facial vein|vein of face|face vein http://purl.obolibrary.org/obo/UBERON_0001653 GO:0000703 biolink:MolecularActivity oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Reactome:R-HSA-110224|Reactome:R-HSA-110226|Reactome:R-HSA-110227 go-plus.json endonuclease III|DNA glycosylase/beta-lyase|endonuclease VIII activity|DNA glycosylase/AP-lyase|oxidized pyrimidine base lesion DNA N-glycosylase activity|bifunctional DNA glycosylase|endodeoxyribonuclease III|pyrimidine-specific oxidized base lesion DNA N-glycosylase activity http://purl.obolibrary.org/obo/GO_0000703 GO:0000702 biolink:MolecularActivity oxidized base lesion DNA N-glycosylase activity Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. go-plus.json http://purl.obolibrary.org/obo/GO_0000702 UBERON:0001652 biolink:AnatomicalEntity left pulmonary artery The pulmonary artery that supplies the left lung. go-plus.json left pulmonary arterial tree|left main pulmonary artery|arteria pulmonalis sinistra http://purl.obolibrary.org/obo/UBERON_0001652 GO:0000701 biolink:MolecularActivity purine-specific mismatch base pair DNA N-glycosylase activity Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site. EC:3.2.2.31 go-plus.json A/G-specific adenine DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0000701 GO:0000700 biolink:MolecularActivity mismatch base pair DNA N-glycosylase activity Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. go-plus.json http://purl.obolibrary.org/obo/GO_0000700 GO:0000707 biolink:BiologicalProcess meiotic DNA recombinase assembly During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0000707 GO:0000706 biolink:BiologicalProcess meiotic DNA double-strand break processing The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0000706 GO:0000705 biolink:BiologicalProcess achiasmate meiosis I The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata. go-plus.json achiasmate meiosis I nuclear division http://purl.obolibrary.org/obo/GO_0000705 UBERON:0001651 biolink:AnatomicalEntity right pulmonary artery The pulmonary artery that supplies the right lung. go-plus.json right pulmonary arterial tree|arteria pulmonalis dextra|right main pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001651 UBERON:0001650 biolink:AnatomicalEntity hypoglossal nerve Cranial nerve that innervates the muscles of the tongue. go-plus.json 12n|hypoglossal nerve/ root|nerve XII|hypoglossal XII|cranial nerve XII|nervi hypoglossalis|twelfth cranial nerve|CN-XII|nervus hypoglossus [xii]|hypoglossal nerve tree|hypoglossal nerve [XII]|nervus hypoglossus|hypoglossal XII nerve http://purl.obolibrary.org/obo/UBERON_0001650 GO:0000704 biolink:MolecularActivity pyrimidine dimer DNA N-glycosylase activity Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. go-plus.json http://purl.obolibrary.org/obo/GO_0000704 UBERON:0001638 biolink:AnatomicalEntity vein Any of the tubular branching vessels that carry blood from the capillaries toward the heart. go-plus.json venous subtree|venae|vena|venous vessel|vascular element|venous tree organ part http://purl.obolibrary.org/obo/UBERON_0001638 GO:0000710 biolink:BiologicalProcess meiotic mismatch repair A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0000710 UBERON:0001637 biolink:AnatomicalEntity artery An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. go-plus.json arterial vessel|arterial tree organ part|arteries|arterial system|arterial subtree http://purl.obolibrary.org/obo/UBERON_0001637 CHEBI:63641 biolink:ChemicalSubstance 9alpha-hydroxyandrosta-1,4-diene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_63641 chebi_ph7_3 CHEBI:63640 biolink:ChemicalSubstance 26-hydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_63640 chebi_ph7_3 CHEBI:38634 biolink:ChemicalSubstance voltage-gated sodium channel blocker go-plus.json http://purl.obolibrary.org/obo/CHEBI_38634 CHEBI:38633 biolink:ChemicalSubstance sodium channel blocker go-plus.json http://purl.obolibrary.org/obo/CHEBI_38633 CHEBI:63644 biolink:ChemicalSubstance 9-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63644 GO:0000719 biolink:BiologicalProcess photoreactive repair The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines. go-plus.json pyrimidine-dimer repair by photolyase http://purl.obolibrary.org/obo/GO_0000719 CHEBI:38632 biolink:ChemicalSubstance membrane transport modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_38632 CHEBI:38637 biolink:ChemicalSubstance tyrosine kinase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_38637 GO:0000714 biolink:BiologicalProcess meiotic strand displacement The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis. go-plus.json meiotic displacement loop processing|meiotic D-loop processing|meiotic displacement loop dissociation|meiotic D-loop dissociation http://purl.obolibrary.org/obo/GO_0000714 GO:0000713 biolink:BiologicalProcess meiotic heteroduplex formation During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0000713 UBERON:0001644 biolink:AnatomicalEntity trochlear nerve A cranial nerve that runs to the eye muscles. go-plus.json trochlear IV nerve|trochlear nerve tree|pathetic nerve|nervus trochlearis [IV]|4n|superior oblique nerve|trochlear nerve [IV]|cranial nerve IV|CN-IV|trochlear nerve/root|nervus trochlearis|nerve IV|fourth cranial nerve|trochlear nerve or its root|trochlear http://purl.obolibrary.org/obo/UBERON_0001644 GO:0000712 biolink:BiologicalProcess resolution of meiotic recombination intermediates The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged. go-plus.json resolution of meiotic joint molecules as recombinants http://purl.obolibrary.org/obo/GO_0000712 UBERON:0001643 biolink:AnatomicalEntity oculomotor nerve Cranial nerve which connects the midbrain to the extra-ocular and intra-ocular muscles. go-plus.json nervus oculomotorius|3n|nerve III|oculomotor nerve or its root|oculomotor nerve [III]|third cranial nerve|occulomotor|cranial nerve III|oculomotor III nerve|oculomotor nerve tree|CN-III|nervus oculomotorius [III]|oculomotor III http://purl.obolibrary.org/obo/UBERON_0001643 GO:0000711 biolink:BiologicalProcess meiotic DNA repair synthesis During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template. go-plus.json http://purl.obolibrary.org/obo/GO_0000711 GO:0000718 biolink:BiologicalProcess nucleotide-excision repair, DNA damage removal The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_0000718 CHEBI:38631 biolink:ChemicalSubstance aminoalkylindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38631 GO:0000717 biolink:BiologicalProcess nucleotide-excision repair, DNA duplex unwinding The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage. go-plus.json http://purl.obolibrary.org/obo/GO_0000717 UBERON:0001640 biolink:AnatomicalEntity celiac artery The first major branch of the abdominal aorta. go-plus.json arteria cœliaca|coeliac artery|celiac trunk|coeliac trunk|coeliac axis|coeliac trunck|truncus cœliacus|celiac tree|arteria coeliaca|truncus coeliacus http://purl.obolibrary.org/obo/UBERON_0001640 GO:0000716 biolink:BiologicalProcess transcription-coupled nucleotide-excision repair, DNA damage recognition The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. go-plus.json pyrimidine-dimer repair, DNA damage recognition http://purl.obolibrary.org/obo/GO_0000716 GO:0000715 biolink:BiologicalProcess nucleotide-excision repair, DNA damage recognition The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix. go-plus.json pyrimidine-dimer repair, DNA damage recognition http://purl.obolibrary.org/obo/GO_0000715 CL:1001509 biolink:Cell glycinergic neuron The neurons that utilize glycine as a neurotransmitter. go-plus.json http://purl.obolibrary.org/obo/CL_1001509 GO:0048703 biolink:BiologicalProcess embryonic viscerocranium morphogenesis The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones. go-plus.json embryonic pharyngeal skeleton morphogenesis http://purl.obolibrary.org/obo/GO_0048703 GO:0048702 biolink:BiologicalProcess embryonic neurocranium morphogenesis The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain. go-plus.json embryonic chondrocranium morphogenesis|embryonic braincase morphogenesis http://purl.obolibrary.org/obo/GO_0048702 CHEBI:38609 biolink:ChemicalSubstance indolecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38609 GO:0048701 biolink:BiologicalProcess embryonic cranial skeleton morphogenesis The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase. go-plus.json embryonic cranium morphogenesis http://purl.obolibrary.org/obo/GO_0048701 CHEBI:38608 biolink:ChemicalSubstance dibenzazecine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38608 GO:0048700 biolink:BiologicalProcess acquisition of desiccation tolerance in seed The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state. go-plus.json acquisition of desiccation tolerance http://purl.obolibrary.org/obo/GO_0048700 CHEBI:38607 biolink:ChemicalSubstance dibenzazecine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38607 CHEBI:87620 biolink:ChemicalSubstance 16beta-hydroxyestradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87620 chebi_ph7_3 CL:1001503 biolink:Cell olfactory bulb tufted cell The principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala. go-plus.json http://purl.obolibrary.org/obo/CL_1001503 CHEBI:63656 biolink:ChemicalSubstance 9beta-pimara-7,15-dien-19-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63656 chebi_ph7_3 CHEBI:87623 biolink:ChemicalSubstance methanediimine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87623 chebi_ph7_3 GO:0048709 biolink:BiologicalProcess oligodendrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0048709 CHEBI:38600 biolink:ChemicalSubstance 4H-pyrazol-4-ide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38600 CHEBI:87626 biolink:ChemicalSubstance 6beta-hydroxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_87626 chebi_ph7_3 CHEBI:63655 biolink:ChemicalSubstance (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63655 GO:0048708 biolink:BiologicalProcess astrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. go-plus.json http://purl.obolibrary.org/obo/GO_0048708 GO:0048707 biolink:BiologicalProcess instar larval or pupal morphogenesis The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048707 CHEBI:38606 biolink:ChemicalSubstance cyclopentapyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_38606 GO:0048706 biolink:BiologicalProcess embryonic skeletal system development The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. go-plus.json embryonic skeletal development http://purl.obolibrary.org/obo/GO_0048706 CHEBI:38605 biolink:ChemicalSubstance phenethylamine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38605 GO:0048705 biolink:BiologicalProcess skeletal system morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. go-plus.json skeletal morphogenesis http://purl.obolibrary.org/obo/GO_0048705 CHEBI:63659 biolink:ChemicalSubstance 9beta-pimara-7,15-dien-19-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63659 chebi_ph7_3 GO:0048704 biolink:BiologicalProcess embryonic skeletal system morphogenesis The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase. go-plus.json embryonic skeletal morphogenesis http://purl.obolibrary.org/obo/GO_0048704 CHEBI:63658 biolink:ChemicalSubstance 9beta-pimara-7,15-dien-19-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_63658 chebi_ph7_3 GO:0048714 biolink:BiologicalProcess positive regulation of oligodendrocyte differentiation Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. go-plus.json up regulation of oligodendrocyte differentiation|activation of oligodendrocyte differentiation|stimulation of oligodendrocyte differentiation|up-regulation of oligodendrocyte differentiation|upregulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0048714 CHEBI:63660 biolink:ChemicalSubstance pravastatin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63660 chebi_ph7_3 GO:0048713 biolink:BiologicalProcess regulation of oligodendrocyte differentiation Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0048713 GO:0048712 biolink:BiologicalProcess negative regulation of astrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. go-plus.json down regulation of astrocyte differentiation|downregulation of astrocyte differentiation|down-regulation of astrocyte differentiation|inhibition of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0048712 GO:0048711 biolink:BiologicalProcess positive regulation of astrocyte differentiation Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. go-plus.json upregulation of astrocyte differentiation|up regulation of astrocyte differentiation|activation of astrocyte differentiation|stimulation of astrocyte differentiation|up-regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0048711 GO:0048710 biolink:BiologicalProcess regulation of astrocyte differentiation Any process that modulates the frequency, rate or extent of astrocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0048710 CHEBI:63664 biolink:ChemicalSubstance taxusin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63664 chebi_ph7_3 CHEBI:63663 biolink:ChemicalSubstance 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63663 chebi_ph7_3 CHEBI:63662 biolink:ChemicalSubstance 11alpha-hydroxy-ent-cassa-12,15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63662 chebi_ph7_3 CHEBI:63668 biolink:ChemicalSubstance abieta-7,13-dien-18,18-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63668 chebi_ph7_3 CHEBI:63665 biolink:ChemicalSubstance 7beta-hydroxytaxusin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63665 chebi_ph7_3 GO:0048719 biolink:BiologicalProcess epistomal sclerite morphogenesis The process in which the anatomical structures of the epistomal sclerite are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048719 GO:0048718 biolink:BiologicalProcess cibarial fish-trap bristle morphogenesis The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium. go-plus.json fish trap bristle morphogenesis http://purl.obolibrary.org/obo/GO_0048718 GO:0048717 biolink:BiologicalProcess anterior cibarial plate morphogenesis The process in which the anatomical structures of the anterior cibarial plate are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048717 GO:0048716 biolink:BiologicalProcess labrum morphogenesis The process in which the anatomical structures of labrum are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048716 CHEBI:38615 biolink:ChemicalSubstance cyclopiazonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38615 GO:0048715 biolink:BiologicalProcess negative regulation of oligodendrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. go-plus.json downregulation of oligodendrocyte differentiation|down-regulation of oligodendrocyte differentiation|inhibition of oligodendrocyte differentiation|down regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0048715 CHEBI:87618 biolink:ChemicalSubstance 15alpha-hydroxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_87618 chebi_ph7_3 GO:0048725 biolink:BiologicalProcess cibarial fish-trap bristle development The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium. go-plus.json fish-trap bristle development http://purl.obolibrary.org/obo/GO_0048725 CHEBI:63671 biolink:ChemicalSubstance TRIBOA beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_63671 chebi_ph7_3 GO:0048724 biolink:BiologicalProcess epistomal sclerite development The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048724 CHEBI:63670 biolink:ChemicalSubstance DIBOA beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_63670 chebi_ph7_3 GO:0048723 biolink:BiologicalProcess clypeus development The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head. go-plus.json http://purl.obolibrary.org/obo/GO_0048723 GO:0048722 biolink:BiologicalProcess anterior cibarial plate development The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048722 GO:0048721 biolink:BiologicalProcess clypeus morphogenesis The process in which the anatomical structures of the clypeus are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048721 GO:0048720 biolink:BiologicalProcess posterior cibarial plate morphogenesis The process in which the anatomical structures of the posterior cibarial plate are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048720 CHEBI:63672 biolink:ChemicalSubstance 3-methoxy-4',5-dihydroxy-trans-stilbene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63672 chebi_ph7_3 CHEBI:63679 biolink:ChemicalSubstance [4)-beta-D-GlcA-(1->4)-beta-D-GlcA2(or 3)Ac-(1->4)-beta-D-Glc-(1->4)-[(R)-4,6-CH3(COO(-))C-beta-D-Gal3(or 2)OHb-(1->3)-(S)-4,6-CH3(COO(-))C-beta-D-Glc-(1->4)-beta-D-Glc-(1->4)-beta-D-Glc-(1->6)]-alpha-DGlc2(or 3)Ac-(1->]n go-plus.json http://purl.obolibrary.org/obo/CHEBI_63679 chebi_ph7_3 PR:000011407 biolink:Protein mineralocorticoid receptor A protein that is a translation product of the human NR3C2 gene or a 1:1 ortholog thereof. go-plus.json MR|NR3C2|nuclear receptor subfamily 3 group C member 2|MCR|MLR http://purl.obolibrary.org/obo/PR_000011407 NCBITaxon:22097 biolink:OrganismalEntity Amborellaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_22097 UBERON:0001691 biolink:AnatomicalEntity external ear Part of the ear external to the tympanum (eardrum). It typically consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull[GO]. go-plus.json auricular region of head|outer ear|auricular region|auris externa http://purl.obolibrary.org/obo/UBERON_0001691 PR:000011406 biolink:Protein glucocorticoid receptor A protein that is a translation product of the human NR3C1 gene or a 1:1 ortholog thereof. go-plus.json GR|NR3C1|GRL|nuclear receptor subfamily 3 group C member 1|Grl1 http://purl.obolibrary.org/obo/PR_000011406 CHEBI:63677 biolink:ChemicalSubstance erythromycin D(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63677 chebi_ph7_3 CHEBI:63676 biolink:ChemicalSubstance dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63676 chebi_ph7_3 UBERON:0001690 biolink:AnatomicalEntity ear Sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. go-plus.json auditory apparatus|auris http://purl.obolibrary.org/obo/UBERON_0001690 GO:0048729 biolink:BiologicalProcess tissue morphogenesis The process in which the anatomical structures of a tissue are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048729 GO:0048728 biolink:BiologicalProcess proboscis development The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048728 GO:0048727 biolink:BiologicalProcess posterior cibarial plate development The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048727 GO:0048726 biolink:BiologicalProcess labrum development The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048726 UBERON:0001697 biolink:AnatomicalEntity orbit of skull Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball. go-plus.json eye socket|bony orbit|orbit of skull|orbit http://purl.obolibrary.org/obo/UBERON_0001697 CL:0001071 biolink:Cell group 3 innate lymphoid cell An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22. go-plus.json ILC3 http://purl.obolibrary.org/obo/CL_0001071 UBERON:0001694 biolink:AnatomicalEntity petrous part of temporal bone The petrous portion of the temporal bone or pyramid is pyramidal and is wedged in at the base of the skull between the sphenoid and occipital bones. Directed medially, forward, and a little upward, it presents for examination a base, an apex, three surfaces, and three angles, and contains, in its interior, the essential parts of the organ of hearing. The petrous portion is among the most basal elements of the skull and forms part of the endocranium.[WP,unvetted]. go-plus.json petromastoid part of temporal bone|pars petrosa (os temporale)|petrosal bone|pars petrosa ossis temporalis|temporal bone petrous part|petrosal|petrous bone http://purl.obolibrary.org/obo/UBERON_0001694 CHEBI:73005 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73005 chebi_ph7_3 CHEBI:73004 biolink:ChemicalSubstance 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73004 chebi_ph7_3 CHEBI:73007 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73007 chebi_ph7_3 CHEBI:73006 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73006 chebi_ph7_3 CHEBI:73009 biolink:ChemicalSubstance 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73009 chebi_ph7_3 UBERON:0001679 biolink:AnatomicalEntity ethmoid bone A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP] go-plus.json ethmoidal bone|os ethmoidale|ethmoid http://purl.obolibrary.org/obo/UBERON_0001679 UBERON:0001678 biolink:AnatomicalEntity temporal bone the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous go-plus.json os temporale http://purl.obolibrary.org/obo/UBERON_0001678 CHEBI:73008 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73008 chebi_ph7_3 GO:0048736 biolink:BiologicalProcess appendage development The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. go-plus.json http://purl.obolibrary.org/obo/GO_0048736 CHEBI:63682 biolink:ChemicalSubstance (5S,9S,10S,13E)-labda-7,13-dien-15-yl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63682 chebi_ph7_3 GO:0048735 biolink:BiologicalProcess haltere morphogenesis The process in which the anatomical structures of a haltere are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048735 GO:0048734 biolink:BiologicalProcess proboscis morphogenesis The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head. go-plus.json http://purl.obolibrary.org/obo/GO_0048734 CHEBI:63680 biolink:ChemicalSubstance CMP-pseudaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63680 chebi_ph7_3 GO:0048733 biolink:BiologicalProcess sebaceous gland development The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048733 GO:0048732 biolink:BiologicalProcess gland development The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0048732 CHEBI:87631 biolink:ChemicalSubstance statin go-plus.json http://purl.obolibrary.org/obo/CHEBI_87631 GO:0048731 biolink:BiologicalProcess system development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. go-plus.json http://purl.obolibrary.org/obo/GO_0048731 goslim_mouse UBERON:0011004 biolink:AnatomicalEntity pharyngeal arch cartilage A cartilage element that is part of a splanchnocranium. go-plus.json splanchnocranium cartilage|pharyngeal arch cartilages http://purl.obolibrary.org/obo/UBERON_0011004 CHEBI:14649 biolink:ChemicalSubstance NMN(-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_14649 chebi_ph7_3 GO:0048730 biolink:BiologicalProcess epidermis morphogenesis The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. go-plus.json hypodermis morphogenesis http://purl.obolibrary.org/obo/GO_0048730 CHEBI:87633 biolink:ChemicalSubstance statin (semi-synthetic) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87633 CHEBI:87632 biolink:ChemicalSubstance statin (naturally occurring) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87632 CHEBI:63683 biolink:ChemicalSubstance (13E)-labda-7,13-dien-15-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_63683 chebi_ph7_3 CHEBI:63689 biolink:ChemicalSubstance P(1),P(6)-bis(5'-adenosyl)hexaphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63689 CHEBI:14648 biolink:ChemicalSubstance NMN(+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_14648 GO:0048739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048739 GO:0048738 biolink:BiologicalProcess cardiac muscle tissue development The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. go-plus.json heart muscle development http://purl.obolibrary.org/obo/GO_0048738 GO:0048737 biolink:BiologicalProcess imaginal disc-derived appendage development The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0048737 UBERON:0001686 biolink:AnatomicalEntity auditory ossicle bone One of 3 small bones contained within the middle ear space and serve to transmit sounds from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means 'tiny bones' and commonly refers to the auditory ossicles, though the term may refer to any small bone throughout the body. [WP,unvetted]. go-plus.json ear ossicle|ossicular chain|middle ear ossicle|auditory bone|ear bone|ossicle of ear|ossicle of inner ear|auditory ossicle|ossicle|ear ossicles|middle ear bone http://purl.obolibrary.org/obo/UBERON_0001686 UBERON:0001685 biolink:AnatomicalEntity hyoid bone A horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. [WP,modified]. go-plus.json hyoid bone|hyoideum|os hyoideum|lingual bone|hyoid http://purl.obolibrary.org/obo/UBERON_0001685 CL:0001082 biolink:Cell immature innate lymphoid cell An innate lyphoid cell with an immature phenotype. go-plus.json immature ILC http://purl.obolibrary.org/obo/CL_0001082 CHEBI:73001 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73001 chebi_ph7_3 UBERON:0001682 biolink:AnatomicalEntity palatine bone A paired dermal bone situated in the mid-palate[Palaeos]. go-plus.json os palatinum|dermopalatine|palate bone|palatum|palatine http://purl.obolibrary.org/obo/UBERON_0001682 UBERON:0001681 biolink:AnatomicalEntity nasal bone One of two small oblong bones, varying in size and form in different individuals; they are placed side by side at the middle and upper part of the face, and form, by their junction, 'the bridge' of the nose[WP]. Paired dermal bones, likened to a bone tube, positioned lateral to the supraethmoid. Nasal bones are transversed by the anterior most part of the supraorbital canals and bear one neuromast foramen in zebrafish[ZFA]. go-plus.json os nasale|nasals|nasal bones http://purl.obolibrary.org/obo/UBERON_0001681 CHEBI:73000 biolink:ChemicalSubstance 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73000 chebi_ph7_3 CHEBI:73003 biolink:ChemicalSubstance 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73003 chebi_ph7_3 CHEBI:73002 biolink:ChemicalSubstance 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73002 chebi_ph7_3 GO:0010128 biolink:BiologicalProcess benzoate catabolic process via CoA ligation The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway. MetaCyc:PWY-283 go-plus.json anaerobic benzoate catabolism|anaerobic benzoate degradation|anaerobic benzoate breakdown|anaerobic benzoate catabolic process http://purl.obolibrary.org/obo/GO_0010128 CHEBI:48052 biolink:ChemicalSubstance 2,3-dihydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48052 GO:0009139 biolink:BiologicalProcess pyrimidine nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine nucleoside diphosphate biosynthesis|pyrimidine nucleoside diphosphate anabolism|pyrimidine nucleoside diphosphate synthesis|pyrimidine nucleoside diphosphate formation http://purl.obolibrary.org/obo/GO_0009139 CHEBI:24085 biolink:ChemicalSubstance formimidoyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24085 GO:0010127 biolink:BiologicalProcess mycothiol-dependent detoxification The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell. MetaCyc:PWY1G-1|MetaCyc:PWY1G-170 go-plus.json mycothiol-dependent detoxification of alkylating agent http://purl.obolibrary.org/obo/GO_0010127 CHEBI:133977 biolink:ChemicalSubstance S-(2,4-dinitrophenyl)glutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133977 chebi_ph7_3 GO:0009138 biolink:BiologicalProcess pyrimidine nucleoside diphosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine nucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009138 GO:0009137 biolink:BiologicalProcess purine nucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json purine nucleoside diphosphate degradation|purine nucleoside diphosphate catabolism|purine nucleoside diphosphate breakdown http://purl.obolibrary.org/obo/GO_0009137 GO:0010129 biolink:BiologicalProcess anaerobic cyclohexane-1-carboxylate catabolic process The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen. MetaCyc:PWY-301 go-plus.json anaerobic cyclohexane-1-carboxylate breakdown|anaerobic cyclohexane-1-carboxylate catabolism|anaerobic cyclohexane-1-carboxylate degradation http://purl.obolibrary.org/obo/GO_0010129 CHEBI:133979 biolink:ChemicalSubstance prostaglandin D2 2-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_133979 chebi_ph7_3 GO:0009136 biolink:BiologicalProcess purine nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json purine nucleoside diphosphate biosynthesis|purine nucleoside diphosphate anabolism|purine nucleoside diphosphate synthesis|purine nucleoside diphosphate formation http://purl.obolibrary.org/obo/GO_0009136 GO:0009135 biolink:BiologicalProcess purine nucleoside diphosphate metabolic process The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json purine nucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009135 GO:0009134 biolink:BiologicalProcess nucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. go-plus.json nucleoside diphosphate degradation|nucleoside diphosphate breakdown|nucleoside diphosphate catabolism http://purl.obolibrary.org/obo/GO_0009134 GO:0009133 biolink:BiologicalProcess nucleoside diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. go-plus.json nucleoside diphosphate synthesis|nucleoside diphosphate formation|nucleoside diphosphate anabolism|nucleoside diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009133 CHEBI:48058 biolink:ChemicalSubstance buten-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48058 chebi_ph7_3 GO:0009132 biolink:BiologicalProcess nucleoside diphosphate metabolic process The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. go-plus.json nucleoside diphosphate metabolism http://purl.obolibrary.org/obo/GO_0009132 GO:0010120 biolink:BiologicalProcess camalexin biosynthetic process The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin. MetaCyc:CAMALEXIN-SYN go-plus.json camalexin anabolism|camalexin synthesis|camalexin formation|camalexin biosynthesis http://purl.obolibrary.org/obo/GO_0010120 GO:0009142 biolink:BiologicalProcess nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. go-plus.json nucleoside triphosphate biosynthesis|nucleoside triphosphate anabolism|nucleoside triphosphate synthesis|nucleoside triphosphate formation http://purl.obolibrary.org/obo/GO_0009142 CHEBI:133970 biolink:ChemicalSubstance N-retinylidene-N-retinylphosphatidylethanolamine betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133970 chebi_ph7_3 GO:0009141 biolink:BiologicalProcess nucleoside triphosphate metabolic process The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. go-plus.json nucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009141 GO:0010122 biolink:BiologicalProcess arginine catabolic process to alanine via ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine. MetaCyc:ARGORNPROST-PWY go-plus.json arginine breakdown to alanine via ornithine|arginine degradation to alanine via ornithine http://purl.obolibrary.org/obo/GO_0010122 CHEBI:133972 biolink:ChemicalSubstance primary nitroalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_133972 chebi_ph7_3 GO:0009140 biolink:BiologicalProcess pyrimidine nucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. go-plus.json pyrimidine nucleoside diphosphate catabolism|pyrimidine nucleoside diphosphate degradation|pyrimidine nucleoside diphosphate breakdown http://purl.obolibrary.org/obo/GO_0009140 GO:0010121 biolink:BiologicalProcess arginine catabolic process to proline via ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine. MetaCyc:ARGORNPROST-PWY go-plus.json arginine breakdown to proline via ornithine|arginine degradation to proline via ornithine http://purl.obolibrary.org/obo/GO_0010121 GO:0010124 biolink:BiologicalProcess phenylacetate catabolic process The chemical reactions and pathways resulting in the breakdown of phenylacetate. MetaCyc:PWY0-321 go-plus.json phenylacetate degradation|phenylacetate breakdown|phenylacetate catabolism http://purl.obolibrary.org/obo/GO_0010124 CHEBI:133974 biolink:ChemicalSubstance 12-oxo-6-trans-leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133974 chebi_ph7_3 GO:0010123 biolink:BiologicalProcess acetate catabolic process to butyrate, ethanol, acetone and butanol The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol. MetaCyc:CENTFERM-PWY go-plus.json acetate fermentation to butyrate, ethanol, acetone and butanol http://purl.obolibrary.org/obo/GO_0010123 GO:0010126 biolink:BiologicalProcess mycothiol metabolic process The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione. go-plus.json mycothiol metabolism http://purl.obolibrary.org/obo/GO_0010126 CHEBI:24090 biolink:ChemicalSubstance formyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_24090 chebi_ph7_3 GO:0010125 biolink:BiologicalProcess mycothiol biosynthetic process The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione. MetaCyc:PWY1G-0 go-plus.json mycothiol biosynthesis|mycothiol anabolism|mycothiol synthesis|mycothiol formation http://purl.obolibrary.org/obo/GO_0010125 CHEBI:133975 biolink:ChemicalSubstance Delta(6)-trans-12-epi-leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133975 chebi_ph7_3 CHEBI:48041 biolink:ChemicalSubstance microcystin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48041 GO:0010139 biolink:BiologicalProcess pyrimidine deoxyribonucleotide salvage The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis. MetaCyc:PWY0-181 go-plus.json http://purl.obolibrary.org/obo/GO_0010139 CHEBI:133989 biolink:ChemicalSubstance (9Z,11R,12Z,15Z)-11-hydroperoxyoctadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133989 chebi_ph7_3 CHEBI:133988 biolink:ChemicalSubstance (9Z,11R,12Z,15Z)-11-hydroperoxyoctadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133988 GO:0009149 biolink:BiologicalProcess pyrimidine nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine nucleoside triphosphate degradation|pyrimidine nucleoside triphosphate breakdown|pyrimidine nucleoside triphosphate catabolism http://purl.obolibrary.org/obo/GO_0009149 GO:0010138 biolink:BiologicalProcess pyrimidine ribonucleotide salvage The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis. MetaCyc:PWY0-163 go-plus.json http://purl.obolibrary.org/obo/GO_0010138 CHEBI:48040 biolink:ChemicalSubstance 2,3-dihydroflavon-3-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48040 chebi_ph7_3 GO:0009148 biolink:BiologicalProcess pyrimidine nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine nucleoside triphosphate synthesis|pyrimidine nucleoside triphosphate formation|pyrimidine nucleoside triphosphate anabolism|pyrimidine nucleoside triphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009148 CHEBI:48043 biolink:ChemicalSubstance (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48043 GO:0009147 biolink:BiologicalProcess pyrimidine nucleoside triphosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json pyrimidine nucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009147 GO:0009146 biolink:BiologicalProcess purine nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json purine nucleoside triphosphate degradation|purine nucleoside triphosphate catabolism|purine nucleoside triphosphate breakdown http://purl.obolibrary.org/obo/GO_0009146 GO:0009145 biolink:BiologicalProcess purine nucleoside triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json purine nucleoside triphosphate anabolism|purine nucleoside triphosphate synthesis|purine nucleoside triphosphate formation|purine nucleoside triphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009145 CHEBI:24099 biolink:ChemicalSubstance formyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24099 GO:0009144 biolink:BiologicalProcess purine nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. go-plus.json purine nucleoside triphosphate metabolism http://purl.obolibrary.org/obo/GO_0009144 GO:0009143 biolink:BiologicalProcess nucleoside triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. go-plus.json nucleoside triphosphate degradation|nucleoside triphosphate breakdown|nucleoside triphosphate catabolism http://purl.obolibrary.org/obo/GO_0009143 GO:0009153 biolink:BiologicalProcess purine deoxyribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine deoxyribonucleotide biosynthesis|purine deoxyribonucleotide anabolism|purine deoxyribonucleotide synthesis|purine deoxyribonucleotide formation http://purl.obolibrary.org/obo/GO_0009153 GO:0010131 biolink:BiologicalProcess obsolete sucrose catabolic process, using invertase or sucrose synthase OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase. MetaCyc:PWY-3801|MetaCyc:PWY-621 go-plus.json sucrose catabolic process, using invertase or sucrose synthase|sucrose breakdown, using invertase or sucrose synthase|sucrose degradation, using invertase or sucrose synthase|sucrose catabolism, using invertase or sucrose synthase http://purl.obolibrary.org/obo/GO_0010131 GO:0009152 biolink:BiologicalProcess purine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine ribonucleotide anabolism|purine ribonucleotide synthesis|purine ribonucleotide formation|purine ribonucleotide biosynthesis http://purl.obolibrary.org/obo/GO_0009152 GO:0010130 biolink:BiologicalProcess anaerobic ethylbenzene catabolic process The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen. MetaCyc:PWY-481 go-plus.json anaerobic ethylbenzene catabolism|anaerobic ethylbenzene degradation|anaerobic ethylbenzene breakdown http://purl.obolibrary.org/obo/GO_0010130 CHEBI:133980 biolink:ChemicalSubstance oxidised coenzyme F420-(gamma-Glu)n polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133980 chebi_ph7_3 GO:0010133 biolink:BiologicalProcess proline catabolic process to glutamate The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate. MetaCyc:PROUT-PWY|MetaCyc:PWY-4561 go-plus.json proline breakdown to glutamate|proline degradation to glutamate|proline oxidation http://purl.obolibrary.org/obo/GO_0010133 GO:0009151 biolink:BiologicalProcess purine deoxyribonucleotide metabolic process The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine deoxyribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009151 GO:0010132 biolink:BiologicalProcess dhurrin biosynthetic process The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound. MetaCyc:PWY-861 go-plus.json dhurrin formation|dhurrin biosynthesis|dhurrin anabolism|dhurrin synthesis http://purl.obolibrary.org/obo/GO_0010132 GO:0009150 biolink:BiologicalProcess purine ribonucleotide metabolic process The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. go-plus.json purine ribonucleotide metabolism http://purl.obolibrary.org/obo/GO_0009150 GO:0010135 biolink:BiologicalProcess ureide metabolic process The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants. go-plus.json ureide metabolism http://purl.obolibrary.org/obo/GO_0010135 CHEBI:133985 biolink:ChemicalSubstance 13(R)-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133985 chebi_ph7_3 GO:0010134 biolink:BiologicalProcess sulfate assimilation via adenylyl sulfate reduction The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase. MetaCyc:SULFMETII-PWY go-plus.json sulphate assimilation via adenylyl sulphate reduction http://purl.obolibrary.org/obo/GO_0010134 GO:0010137 biolink:BiologicalProcess ureide biosynthetic process The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots. MetaCyc:URSIN-PWY go-plus.json ureide anabolism|ureide synthesis|ureide formation|ureide biosynthesis http://purl.obolibrary.org/obo/GO_0010137 CHEBI:133987 biolink:ChemicalSubstance (9Z,11E,13R,15Z)-13-hydroperoxyoctadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133987 chebi_ph7_3 GO:0010136 biolink:BiologicalProcess ureide catabolic process The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium. MetaCyc:URDEGR-PWY go-plus.json ureide degradation|ureide breakdown|ureide catabolism http://purl.obolibrary.org/obo/GO_0010136 CHEBI:133986 biolink:ChemicalSubstance (9Z,11E,13R,15Z)-13-hydroperoxyoctadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133986 GO:0000783 biolink:CellularComponent nuclear telomere cap complex A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000783 GO:0097695 biolink:BiologicalProcess establishment of protein-containing complex localization to telomere The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome. go-plus.json establishment of macromolecular complex localisation to telomere|establishment of macromolecular complex localization to telomere http://purl.obolibrary.org/obo/GO_0097695 GO:0000782 biolink:CellularComponent telomere cap complex A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0000782 goslim_pir GO:0097694 biolink:BiologicalProcess establishment of RNA localization to telomere The directed movement of RNA to a specific location in the telomeric region of a chromosome. go-plus.json establishment of RNA localisation to telomere http://purl.obolibrary.org/obo/GO_0097694 GO:0000781 biolink:CellularComponent chromosome, telomeric region The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). SO:0000624 go-plus.json nuclear chromosome, telomeric region|telomere|nuclear chromosome, telomere http://purl.obolibrary.org/obo/GO_0000781 GO:0097697 biolink:MolecularActivity tRNA 5-carboxymethoxyuridine methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0097697 GO:0000780 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000780 CHEBI:48039 biolink:ChemicalSubstance dihydroflavonols go-plus.json http://purl.obolibrary.org/obo/CHEBI_48039 chebi_ph7_3 GO:0097696 biolink:BiologicalProcess receptor signaling pathway via STAT An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins. go-plus.json STAT signalling pathway|kinase-STAT cascade|kinase activated-STAT cascade http://purl.obolibrary.org/obo/GO_0097696 CHEBI:24068 biolink:ChemicalSubstance fluoroamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24068 GO:0097691 biolink:CellularComponent bacterial extracellular vesicle Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells. go-plus.json http://purl.obolibrary.org/obo/GO_0097691 GO:0000787 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000787 GO:0000786 biolink:CellularComponent nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. Wikipedia:Nucleosome go-plus.json cytoplasmic nucleosome|nuclear nucleosome http://purl.obolibrary.org/obo/GO_0000786 goslim_pir GO:0097690 biolink:MolecularActivity iron ion transmembrane transporter inhibitor activity Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter. go-plus.json iron channel inhibitor activity http://purl.obolibrary.org/obo/GO_0097690 GO:0097693 biolink:CellularComponent ocelloid Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids. go-plus.json http://purl.obolibrary.org/obo/GO_0097693 GO:0000785 biolink:CellularComponent chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. NIF_Subcellular:sao1615953555 go-plus.json chromosome scaffold|cytoplasmic chromatin|nuclear chromatin http://purl.obolibrary.org/obo/GO_0000785 GO:0009119 biolink:BiologicalProcess ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json ribonucleoside metabolism http://purl.obolibrary.org/obo/GO_0009119 GO:0009118 biolink:BiologicalProcess regulation of nucleoside metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. go-plus.json regulation of nucleoside metabolism http://purl.obolibrary.org/obo/GO_0009118 GO:0000784 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000784 GO:0097692 biolink:BiologicalProcess histone H3-K4 monomethylation The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0097692 GO:0009117 biolink:BiologicalProcess nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). go-plus.json nucleotide metabolism http://purl.obolibrary.org/obo/GO_0009117 goslim_pir GO:0010106 biolink:BiologicalProcess cellular response to iron ion starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions. go-plus.json http://purl.obolibrary.org/obo/GO_0010106 CHEBI:48030 biolink:ChemicalSubstance tetrapeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48030 GO:0010105 biolink:BiologicalProcess negative regulation of ethylene-activated signaling pathway Any process that stops or prevents ethylene (ethene) signal transduction. go-plus.json inhibition of ethylene mediated signaling pathway|negative regulation of ethene mediated signalling pathway|negative regulation of ethene mediated signaling pathway|down regulation of ethylene mediated signaling pathway|downregulation of ethylene mediated signaling pathway|negative regulation of ethylene mediated signalling pathway|down-regulation of ethylene mediated signaling pathway|negative regulation of ethylene mediated signaling pathway http://purl.obolibrary.org/obo/GO_0010105 CHEBI:24062 biolink:ChemicalSubstance fluorine molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_24062 GO:0009116 biolink:BiologicalProcess nucleoside metabolic process The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine). go-plus.json nucleoside metabolism http://purl.obolibrary.org/obo/GO_0009116 goslim_pir GO:0010108 biolink:BiologicalProcess detection of glutamine The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal. go-plus.json glutamine sensing|glutamine detection|glutamine perception http://purl.obolibrary.org/obo/GO_0010108 GO:0009115 biolink:BiologicalProcess xanthine catabolic process The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids. go-plus.json xanthine oxidation|xanthine degradation|xanthine catabolism|xanthine breakdown http://purl.obolibrary.org/obo/GO_0009115 CHEBI:24061 biolink:ChemicalSubstance fluorine atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_24061 chebi_ph7_3 CHEBI:48032 biolink:ChemicalSubstance 4-methylene-D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48032 GO:0009114 biolink:BiologicalProcess hypoxanthine catabolic process The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate. go-plus.json hypoxanthine degradation|hypoxanthine breakdown|hypoxanthine catabolism|hypoxanthine oxidation http://purl.obolibrary.org/obo/GO_0009114 GO:0010107 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0010107 CHEBI:48031 biolink:ChemicalSubstance 4-methylene-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48031 GO:0009113 biolink:BiologicalProcess purine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. MetaCyc:PWY-841 go-plus.json purine base anabolism|purine base synthesis|purine base formation|purine base biosynthesis|purine base biosynthetic process http://purl.obolibrary.org/obo/GO_0009113 CHEBI:48034 biolink:ChemicalSubstance cob(III)yrinic acid a,c diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48034 CHEBI:24067 biolink:ChemicalSubstance fluoroalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_24067 GO:0009112 biolink:BiologicalProcess nucleobase metabolic process The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. go-plus.json nucleobase metabolism http://purl.obolibrary.org/obo/GO_0009112 CHEBI:133959 biolink:ChemicalSubstance 4'-methoxyisoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_133959 chebi_ph7_3 GO:0010109 biolink:BiologicalProcess regulation of photosynthesis Any process that modulates the frequency, rate or extent of photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0010109 CHEBI:48033 biolink:ChemicalSubstance cobyrinic acid a,c diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48033 GO:0009111 biolink:BiologicalProcess vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json vitamin catabolism|vitamin degradation|vitamin breakdown http://purl.obolibrary.org/obo/GO_0009111 GO:0009110 biolink:BiologicalProcess vitamin biosynthetic process The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json vitamin biosynthesis|vitamin anabolism|vitamin synthesis|vitamin formation http://purl.obolibrary.org/obo/GO_0009110 GO:0009120 biolink:BiologicalProcess deoxyribonucleoside metabolic process The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json deoxyribonucleoside metabolism http://purl.obolibrary.org/obo/GO_0009120 CHEBI:133950 biolink:ChemicalSubstance (7Z,11Z,13Z,15E,19Z)-10,17-bis(hydroperoxy)docosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133950 chebi_ph7_3 GO:0010100 biolink:BiologicalProcess negative regulation of photomorphogenesis Any process that stops, reduces or prevents photomorphogenesis. go-plus.json down-regulation of photomorphogenesis|downregulation of photomorphogenesis|down regulation of photomorphogenesis|inhibition of photomorphogenesis http://purl.obolibrary.org/obo/GO_0010100 GO:0010102 biolink:BiologicalProcess lateral root morphogenesis The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper. go-plus.json http://purl.obolibrary.org/obo/GO_0010102 GO:0010101 biolink:BiologicalProcess post-embryonic root morphogenesis The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed. go-plus.json http://purl.obolibrary.org/obo/GO_0010101 GO:0010104 biolink:BiologicalProcess regulation of ethylene-activated signaling pathway Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction. go-plus.json regulation of ethene mediated signaling pathway|regulation of ethylene mediated signalling pathway|regulation of ethene mediated signalling pathway|regulation of ethylene mediated signaling pathway http://purl.obolibrary.org/obo/GO_0010104 GO:0010103 biolink:BiologicalProcess stomatal complex morphogenesis The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0010103 GO:0000789 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000789 GO:0000788 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000788 GO:0097699 biolink:BiologicalProcess vascular endothelial cell response to fluid shear stress Any response to fluid shear stress in a vascular endothelial cell. go-plus.json blood vessel endothelial cell response to fluid shear stress http://purl.obolibrary.org/obo/GO_0097699 GO:0097698 biolink:BiologicalProcess telomere maintenance via base-excision repair A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature. go-plus.json http://purl.obolibrary.org/obo/GO_0097698 GO:0000794 biolink:CellularComponent condensed nuclear chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome. go-plus.json nuclear mitotic chromosome|meiotic chromosome http://purl.obolibrary.org/obo/GO_0000794 GO:0000793 biolink:CellularComponent condensed chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. go-plus.json cytoplasmic mitotic chromosome|metaphase chromosome|mitotic chromosome http://purl.obolibrary.org/obo/GO_0000793 GO:0000792 biolink:CellularComponent heterochromatin A compact and highly condensed form of chromatin. Wikipedia:Heterochromatin|NIF_Subcellular:sao581845896 go-plus.json nuclear heterochromatin http://purl.obolibrary.org/obo/GO_0000792 CHEBI:48029 biolink:ChemicalSubstance 4-methyleneglutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48029 GO:0000791 biolink:CellularComponent euchromatin A dispersed and relatively uncompacted form of chromatin. Wikipedia:Euchromatin|NIF_Subcellular:sao445485807 go-plus.json nuclear euchromatin http://purl.obolibrary.org/obo/GO_0000791 CHEBI:24079 biolink:ChemicalSubstance formamides go-plus.json http://purl.obolibrary.org/obo/CHEBI_24079 GO:0000798 biolink:CellularComponent nuclear cohesin complex A cohesin complex required for cohesion between sister chromatids that remain in the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0000798 GO:0000797 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000797 GO:0000796 biolink:CellularComponent condensin complex A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis. go-plus.json SMC complex|13S condensin complex|condensin I complex|nuclear condensin complex|Smc2-Smc4 complex|condensin core heterodimer|8S condensin complex http://purl.obolibrary.org/obo/GO_0000796 goslim_pir GO:0009129 biolink:BiologicalProcess pyrimidine nucleoside monophosphate metabolic process The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine nucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009129 GO:0000795 biolink:CellularComponent synaptonemal complex A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element. Wikipedia:Synaptonemal_complex go-plus.json http://purl.obolibrary.org/obo/GO_0000795 GO:0009128 biolink:BiologicalProcess purine nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. go-plus.json purine nucleoside monophosphate degradation|purine nucleoside monophosphate breakdown|purine nucleoside monophosphate catabolism http://purl.obolibrary.org/obo/GO_0009128 GO:0010117 biolink:BiologicalProcess photoprotection Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0010117 GO:0010116 biolink:BiologicalProcess positive regulation of abscisic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid. go-plus.json stimulation of abscisic acid biosynthetic process|up-regulation of abscisic acid biosynthetic process|activation of abscisic acid biosynthetic process|positive regulation of abscisic acid anabolism|positive regulation of abscisic acid synthesis|positive regulation of abscisic acid formation|positive regulation of abscisic acid biosynthesis|up regulation of abscisic acid biosynthetic process|upregulation of abscisic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0010116 GO:0009127 biolink:BiologicalProcess purine nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. go-plus.json purine nucleoside monophosphate anabolism|purine nucleoside monophosphate synthesis|purine nucleoside monophosphate formation|purine nucleoside monophosphate biosynthesis http://purl.obolibrary.org/obo/GO_0009127 GO:0009126 biolink:BiologicalProcess purine nucleoside monophosphate metabolic process The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. go-plus.json purine nucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009126 CHEBI:133969 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133969 chebi_ph7_3 GO:0010119 biolink:BiologicalProcess regulation of stomatal movement Any process that modulates the frequency, rate or extent of stomatal movement. go-plus.json http://purl.obolibrary.org/obo/GO_0010119 CHEBI:133968 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133968 chebi_ph7_3 GO:0009125 biolink:BiologicalProcess nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. go-plus.json nucleoside monophosphate breakdown|nucleoside monophosphate catabolism|nucleoside monophosphate degradation http://purl.obolibrary.org/obo/GO_0009125 GO:0010118 biolink:BiologicalProcess stomatal movement The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata). go-plus.json http://purl.obolibrary.org/obo/GO_0010118 goslim_pir GO:0009124 biolink:BiologicalProcess nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. go-plus.json nucleoside monophosphate anabolism|nucleoside monophosphate synthesis|nucleoside monophosphate biosynthesis|nucleoside monophosphate formation http://purl.obolibrary.org/obo/GO_0009124 GO:0000790 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000790 GO:0009123 biolink:BiologicalProcess nucleoside monophosphate metabolic process The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. go-plus.json nucleoside monophosphate metabolism http://purl.obolibrary.org/obo/GO_0009123 GO:0009122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009122 CHEBI:48025 biolink:ChemicalSubstance 3',5'-dihydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_48025 chebi_ph7_3 GO:0009121 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009121 CHEBI:48024 biolink:ChemicalSubstance 3'-hydroxyflavanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_48024 GO:0009131 biolink:BiologicalProcess pyrimidine nucleoside monophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine nucleoside monophosphate catabolism|pyrimidine nucleoside monophosphate degradation|pyrimidine nucleoside monophosphate breakdown http://purl.obolibrary.org/obo/GO_0009131 GO:0009130 biolink:BiologicalProcess pyrimidine nucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. go-plus.json pyrimidine nucleoside monophosphate biosynthesis|pyrimidine nucleoside monophosphate anabolism|pyrimidine nucleoside monophosphate synthesis|pyrimidine nucleoside monophosphate formation http://purl.obolibrary.org/obo/GO_0009130 GO:0010111 biolink:BiologicalProcess glyoxysome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway. go-plus.json glyoxysome organisation|glyoxysome organization and biogenesis http://purl.obolibrary.org/obo/GO_0010111 GO:0010110 biolink:BiologicalProcess regulation of photosynthesis, dark reaction Any process that modulates the frequency, rate or extent of photosynthesis dark reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0010110 GO:0010113 biolink:BiologicalProcess negative regulation of systemic acquired resistance Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance. go-plus.json downregulation of systemic acquired resistance|down regulation of systemic acquired resistance|inhibition of systemic acquired resistance|down-regulation of systemic acquired resistance http://purl.obolibrary.org/obo/GO_0010113 GO:0010112 biolink:BiologicalProcess regulation of systemic acquired resistance Any process that modulates the frequency, rate or extent of systemic acquired resistance. go-plus.json http://purl.obolibrary.org/obo/GO_0010112 GO:0010115 biolink:BiologicalProcess regulation of abscisic acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid. go-plus.json regulation of abscisic acid synthesis|regulation of abscisic acid formation|regulation of abscisic acid biosynthesis|regulation of abscisic acid anabolism http://purl.obolibrary.org/obo/GO_0010115 GO:0010114 biolink:BiologicalProcess response to red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json response to red light stimulus http://purl.obolibrary.org/obo/GO_0010114 GO:0000799 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000799 UBERON:0001628 biolink:AnatomicalEntity posterior communicating artery One of a pair of right-sided and left-sided blood vessels in the circle of Willis. It connects the three cerebral arteries of the same side. Anteriorly, it is one portion of the terminal trifurcation of the internal carotid artery. The anterior cerebral artery and the middle cerebral artery are the other two branches of the trifurcation. Posteriorly, it communicates with the posterior cerebral artery. go-plus.json PCS|caudal communicating segment|posterior communicating segment of the basilar artery|arteria cerebri communicans posterior|PCA http://purl.obolibrary.org/obo/UBERON_0001628 GO:0000761 biolink:BiologicalProcess conjugant formation During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing. go-plus.json http://purl.obolibrary.org/obo/GO_0000761 GO:0000760 biolink:BiologicalProcess adaptation to pheromone regulating conjugation with mutual genetic exchange In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. go-plus.json desensitization to pheromone during conjugation without cellular fusion|adaptation to pheromone involved conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000760 GO:0000765 biolink:BiologicalProcess response to pheromone regulating pheromone-induced unidirectional conjugation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation. go-plus.json response to pheromone during pheromone-induced unidirectional http://purl.obolibrary.org/obo/GO_0000765 GO:0000764 biolink:BiologicalProcess obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation. go-plus.json cellular morphogenesis involved in pheromone-induced unidirectional conjugation|cellular morphogenesis during pheromone-induced unidirectional http://purl.obolibrary.org/obo/GO_0000764 GO:0000763 biolink:BiologicalProcess obsolete cell morphogenesis involved in unidirectional conjugation OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation. go-plus.json cell morphogenesis involved in unidirectional conjugation http://purl.obolibrary.org/obo/GO_0000763 GO:0000762 biolink:BiologicalProcess pheromone-induced unidirectional conjugation The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. go-plus.json http://purl.obolibrary.org/obo/GO_0000762 CHEBI:133934 biolink:ChemicalSubstance (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133934 chebi_ph7_3 CHEBI:24041 biolink:ChemicalSubstance flavin mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24041 CHEBI:133933 biolink:ChemicalSubstance (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133933 chebi_ph7_3 CHEBI:24040 biolink:ChemicalSubstance flavin adenine dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24040 CHEBI:133936 biolink:ChemicalSubstance (7Z,10Z,13Z,19Z)-16,17-epoxydocosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133936 chebi_ph7_3 CHEBI:133935 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-19,20-epoxydocosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133935 chebi_ph7_3 CHEBI:133938 biolink:ChemicalSubstance (7Z,13Z,16Z,19Z)-10,11-epoxydocosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133938 chebi_ph7_3 CHEBI:133937 biolink:ChemicalSubstance (7Z,10Z,16Z,19Z)-13,14-epoxydocosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133937 chebi_ph7_3 CHEBI:24043 biolink:ChemicalSubstance flavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_24043 chebi_ph7_3 CHEBI:133939 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-20-hydroxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133939 chebi_ph7_3 CHEBI:38687 biolink:ChemicalSubstance monohydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38687 CHEBI:133930 biolink:ChemicalSubstance 5alpha-androst-1-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_133930 chebi_ph7_3 CHEBI:133932 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,19Z)-16,17-epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133932 chebi_ph7_3 CHEBI:133931 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133931 chebi_ph7_3 GO:0000769 biolink:BiologicalProcess syncytium formation by mitosis without cytokinesis The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis. go-plus.json syncytium formation by mitosis without cell division http://purl.obolibrary.org/obo/GO_0000769 GO:0000768 biolink:BiologicalProcess syncytium formation by plasma membrane fusion The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. go-plus.json cell fusion http://purl.obolibrary.org/obo/GO_0000768 UBERON:0001630 biolink:AnatomicalEntity muscle organ Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. go-plus.json muscle http://purl.obolibrary.org/obo/UBERON_0001630 GO:0000767 biolink:BiologicalProcess cell morphogenesis involved in conjugation The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types. go-plus.json http://purl.obolibrary.org/obo/GO_0000767 GO:0000766 biolink:BiologicalProcess negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses. go-plus.json desensitization to pheromone during pheromone-induced unidirectional conjugation|negative adaptation of signalling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation|adaptation to pheromone during pheromone-induced unidirectional conjugation http://purl.obolibrary.org/obo/GO_0000766 CHEBI:38686 biolink:ChemicalSubstance dihydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38686 CHEBI:38685 biolink:ChemicalSubstance 1,2-epoxypropane go-plus.json http://purl.obolibrary.org/obo/CHEBI_38685 chebi_ph7_3 CHEBI:38684 biolink:ChemicalSubstance tetrahydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38684 GO:0000772 biolink:MolecularActivity mating pheromone activity The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted. go-plus.json http://purl.obolibrary.org/obo/GO_0000772 CHEBI:48005 biolink:ChemicalSubstance gamma-L-glutamylputrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48005 GO:0000771 biolink:BiologicalProcess agglutination involved in conjugation The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation. go-plus.json http://purl.obolibrary.org/obo/GO_0000771 UBERON:0001616 biolink:AnatomicalEntity maxillary artery An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]. go-plus.json internal maxillary artery|arteria maxillaris http://purl.obolibrary.org/obo/UBERON_0001616 CHEBI:24059 biolink:ChemicalSubstance fluorenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_24059 GO:0000770 biolink:BiologicalProcess peptide pheromone export The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones. go-plus.json a-factor export http://purl.obolibrary.org/obo/GO_0000770 UBERON:0001619 biolink:AnatomicalEntity ophthalmic artery The ophthalmic artery is a branch of the internal carotid artery which supplies branches to supply the eye and other structures in the orbit. It enters the orbit together with the Optic nerve through the Optic foramen/canal. [WP,modified]. go-plus.json arteria ophthalmica|opthalmic artery http://purl.obolibrary.org/obo/UBERON_0001619 CHEBI:48007 biolink:ChemicalSubstance N-[(E)-4-aminobutylidene]propane-1,3-diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48007 CHEBI:24057 biolink:ChemicalSubstance fluoren-9-ones go-plus.json http://purl.obolibrary.org/obo/CHEBI_24057 CHEBI:48006 biolink:ChemicalSubstance gamma-glutamylputrescine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48006 GO:0000776 biolink:CellularComponent kinetochore A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. Wikipedia:Kinetochore go-plus.json condensed nuclear chromosome kinetochore|condensed chromosome kinetochore http://purl.obolibrary.org/obo/GO_0000776 goslim_pir GO:0000775 biolink:CellularComponent chromosome, centromeric region The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. SO:0000577 go-plus.json chromosome, centric region|centromere|chromosome, pericentric region|centromere complex http://purl.obolibrary.org/obo/GO_0000775 GO:0009109 biolink:BiologicalProcess obsolete coenzyme catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. go-plus.json coenzyme degradation|coenzyme and prosthetic group catabolic process|coenzyme breakdown|coenzyme and prosthetic group catabolism|coenzyme catabolism http://purl.obolibrary.org/obo/GO_0009109 UBERON:0001612 biolink:AnatomicalEntity facial artery A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]. go-plus.json external maxillary artery|arteria maxillaris externa http://purl.obolibrary.org/obo/UBERON_0001612 GO:0009108 biolink:BiologicalProcess obsolete coenzyme biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. go-plus.json coenzyme anabolism|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group biosynthesis|coenzyme biosynthesis|coenzyme synthesis|coenzyme formation http://purl.obolibrary.org/obo/GO_0009108 GO:0000774 biolink:MolecularActivity adenyl-nucleotide exchange factor activity Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins. Reactome:R-HSA-5252079 go-plus.json http://purl.obolibrary.org/obo/GO_0000774 GO:0009107 biolink:BiologicalProcess lipoate biosynthetic process The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. go-plus.json lipoate biosynthesis|lipoate anabolism|lipoate synthesis|lipoate formation|lipoic acid biosynthetic process|lipoic acid biosynthesis|lipoic acid anabolism|lipoic acid synthesis|lipoic acid formation http://purl.obolibrary.org/obo/GO_0009107 GO:0000773 biolink:MolecularActivity phosphatidyl-N-methylethanolamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine. RHEA:32735|EC:2.1.1.71|MetaCyc:2.1.1.71-RXN go-plus.json phosphatidylethanolamine methyltransferase I|methyltransferase II|phospholipid methyltransferase activity|S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity|PLMT|phosphatidyl-N-methylethanolamine methyltransferase activity|phosphatidylmonomethylethanolamine methyltransferase activity|phosphatidyl-N-monomethylethanolamine methyltransferase activity http://purl.obolibrary.org/obo/GO_0000773 GO:0009106 biolink:BiologicalProcess lipoate metabolic process The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. go-plus.json lipoate metabolism|lipoic acid metabolic process|lipoic acid metabolism http://purl.obolibrary.org/obo/GO_0009106 GO:0009105 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009105 GO:0009104 biolink:BiologicalProcess lipopolysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. go-plus.json lipopolysaccharide degradation|LPS catabolic process|lipopolysaccharide breakdown|lipopolysaccharide catabolism http://purl.obolibrary.org/obo/GO_0009104 GO:0009103 biolink:BiologicalProcess lipopolysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. KEGG_PATHWAY:map00540 go-plus.json lipopolysaccharide biosynthesis|lipopolysaccharide anabolism|LPS biosynthetic process|lipopolysaccharide synthesis|lipopolysaccharide formation http://purl.obolibrary.org/obo/GO_0009103 GO:0009102 biolink:BiologicalProcess biotin biosynthetic process The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid. MetaCyc:BIOTIN-SYNTHESIS-PWY go-plus.json vitamin H biosynthesis|vitamin H biosynthetic process|vitamin B7 biosynthesis|vitamin B7 biosynthetic process|biotin anabolism|biotin synthesis|biotin formation|biotin biosynthesis http://purl.obolibrary.org/obo/GO_0009102 CHEBI:48001 biolink:ChemicalSubstance protein synthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_48001 CHEBI:133949 biolink:ChemicalSubstance (4Z,7Z,11Z,13Z,15E,17S)-10,17-bis(hydroperoxy)docosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133949 chebi_ph7_3 GO:0009101 biolink:BiologicalProcess glycoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. go-plus.json glycoprotein biosynthesis|glycoprotein anabolism|glycoprotein synthesis|glycoprotein formation http://purl.obolibrary.org/obo/GO_0009101 CHEBI:133948 biolink:ChemicalSubstance (4Z,7Z,11Z,13Z,15E,17S,19Z)-10,17-bis(hydroperoxy)docosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133948 chebi_ph7_3 CHEBI:48000 biolink:ChemicalSubstance 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_48000 GO:0009100 biolink:BiologicalProcess glycoprotein metabolic process The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. go-plus.json glycoprotein metabolism http://purl.obolibrary.org/obo/GO_0009100 goslim_drosophila CHEBI:133941 biolink:ChemicalSubstance (3S,5R,10R,12S,14S,15R,16R)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_133941 chebi_ph7_3 CHEBI:133940 biolink:ChemicalSubstance lithocholate sulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133940 chebi_ph7_3 GO:0000779 biolink:CellularComponent condensed chromosome, centromeric region The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. go-plus.json condensed chromosome, pericentric region|condensed chromosome, centric region|condensed chromosome, centromere|condensed nuclear chromosome, centromeric region http://purl.obolibrary.org/obo/GO_0000779 CHEBI:38691 biolink:ChemicalSubstance flavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_38691 chebi_ph7_3 UBERON:0001622 biolink:AnatomicalEntity lacrimal artery The lacrimal artery arises close to the optic foramen, and is one of the largest branches derived from the ophthalmic artery: not infrequently it is given off before the artery enters the orbit. It accompanies the lacrimal nerve along the upper border of the Lateral Rectus, supplies the lacrimal gland. [WP,unvetted]. go-plus.json a. lacrimalis http://purl.obolibrary.org/obo/UBERON_0001622 GO:0000778 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000778 UBERON:0001621 biolink:AnatomicalEntity coronary artery An artery that supplies the myocardium. go-plus.json coronary vessel|coronary arterial tree http://purl.obolibrary.org/obo/UBERON_0001621 GO:0000777 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0000777 CHEBI:38697 biolink:ChemicalSubstance anthocyanin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38697 CHEBI:38695 biolink:ChemicalSubstance anthocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_38695 UBERON:0001606 biolink:AnatomicalEntity muscle of iris . go-plus.json iris muscle|muscle organ of iris|iris muscle organ http://purl.obolibrary.org/obo/UBERON_0001606 CHEBI:24027 biolink:ChemicalSubstance fatty-acyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24027 UBERON:0001605 biolink:AnatomicalEntity ciliary muscle The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. go-plus.json Bowman`s muscles|ciliaris|musculus ciliaris|musculus ciliarus http://purl.obolibrary.org/obo/UBERON_0001605 CHEBI:24026 biolink:ChemicalSubstance fatty alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24026 chebi_ph7_3 UBERON:0001608 biolink:AnatomicalEntity dilatator pupillae A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]. go-plus.json pupillary dilator|pupillary muscle|iris dilator muscle|pupil dilator muscle|musculus dilatator pupillae|musculus dilator pupillae|dilator muscle of pupil|radial muscle of iris|radial muscle|dilator pupillae muscle|iris dilator|pupillary dilator muscle|dilator of pupil|radiating fibers|dilator pupillae muscle|pupil dilator|dilator pupillae|musculus dilatator pupillae http://purl.obolibrary.org/obo/UBERON_0001608 UBERON:0001607 biolink:AnatomicalEntity sphincter pupillae A sphincter muscle that is part of the iris. go-plus.json circular fibers|sphincter muscle of pupil|spincter pupillae|iris sphincter|iris constrictor|sphincter pupillae muscle|pupillary sphincter muscle|pupillary constrictor muscle|M. sphincter pupillae|pupillary sphincter|iris sphincter muscle|constrictor pupillae|sphincter pupillae|m. sphincter pupillae|iris constrictor muscle|musculus sphincter pupillae http://purl.obolibrary.org/obo/UBERON_0001607 GO:0000743 biolink:BiologicalProcess nuclear migration involved in conjugation with cellular fusion The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion. go-plus.json nuclear congression|nuclear migration during conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0000743 UBERON:0001602 biolink:AnatomicalEntity medial rectus extraocular muscle The medial rectus muscle is a muscle in the orbit. As with most of the muscles of the orbit, it is innervated by the inferior division of the oculomotor nerve (Cranial Nerve III). This muscle shares an origin with several other extrinsic eye muscles, the anulus tendineus, or common tendon. It is the largest of the extraocular muscles and its only action is adduction of the eyeball. [WP,unvetted]. go-plus.json musculus rectus medialis|medial rectus|musculus rectus medialis bulbi|medial rectus muscle|m. rectus medialis|medial rectus extraocular muscle|medial recti http://purl.obolibrary.org/obo/UBERON_0001602 GO:0000742 biolink:BiologicalProcess karyogamy involved in conjugation with cellular fusion During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy. go-plus.json karyogamy during conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0000742 UBERON:0001601 biolink:AnatomicalEntity extra-ocular muscle Skeletal muscle derived from cranial mesoderm and controls eye movements. go-plus.json musculi externi bulbi oculi|extraocular musculature|extra-ocular skeletal muscle|extrinsic muscle of eyeball|extrinsic ocular muscle|extrinsic eye muscle|extraocular muscle|extraocular skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001601 GO:0000741 biolink:BiologicalProcess karyogamy The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. Wikipedia:Karyogamy go-plus.json nuclear fusion|nuclear fusion during karyogamy http://purl.obolibrary.org/obo/GO_0000741 GO:0000740 biolink:BiologicalProcess nuclear membrane fusion The joining of 2 or more lipid bilayer membranes that surround the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0000740 UBERON:0001603 biolink:AnatomicalEntity lateral rectus extra-ocular muscle The lateral rectus muscle is a muscle in the orbit. It is one of six extraocular muscles that control the movements of the eye (abduction in this case) and the only muscle innervated by the abducens nerve, cranial nerve VI. [WP,unvetted]. go-plus.json lateral rectus extraocular muscle|lateral recti|musculus rectus lateralis|musculus rectus lateralis bulbi|lateral rectus|lateral extraocular muscle|lateral rectus muscle|posterior rectus|M. rectus lateralis http://purl.obolibrary.org/obo/UBERON_0001603 CHEBI:24028 biolink:ChemicalSubstance iron(3+) chelator go-plus.json http://purl.obolibrary.org/obo/CHEBI_24028 CHEBI:133912 biolink:ChemicalSubstance alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133912 CHEBI:133911 biolink:ChemicalSubstance alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133911 CHEBI:133917 biolink:ChemicalSubstance ochratoxin alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_133917 CHEBI:24020 biolink:ChemicalSubstance fat-soluble vitamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_24020 CHEBI:38668 biolink:ChemicalSubstance purinecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38668 CHEBI:38667 biolink:ChemicalSubstance purinemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38667 CHEBI:133910 biolink:ChemicalSubstance 2-trans-abscisic acid D-glucosyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_133910 chebi_ph7_3 GO:0000747 biolink:BiologicalProcess conjugation with cellular fusion A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae. go-plus.json cell fusion|mating http://purl.obolibrary.org/obo/GO_0000747 goslim_pombe GO:0000746 biolink:BiologicalProcess conjugation The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms. Wikipedia:Conjugation go-plus.json http://purl.obolibrary.org/obo/GO_0000746 goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus GO:0000745 biolink:BiologicalProcess nuclear migration involved in conjugation with mutual genetic exchange The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion. go-plus.json nuclear exchange during conjugation without cellular fusion|nuclear migration involved in conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000745 GO:0000744 biolink:BiologicalProcess karyogamy involved in conjugation with mutual genetic exchange During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena. go-plus.json karyogamy involved in conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000744 UBERON:0001610 biolink:AnatomicalEntity lingual artery The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]. go-plus.json lingual branch of external carotid artery|arteria lingualis http://purl.obolibrary.org/obo/UBERON_0001610 GO:0000749 biolink:BiologicalProcess response to pheromone triggering conjugation with cellular fusion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae. go-plus.json response to pheromone during conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0000749 GO:0000748 biolink:BiologicalProcess conjugation with mutual genetic exchange A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange. go-plus.json conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000748 GO:0000750 biolink:BiologicalProcess pheromone-dependent signal transduction involved in conjugation with cellular fusion A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae. go-plus.json transduction of mating signal http://purl.obolibrary.org/obo/GO_0000750 GO:0000754 biolink:BiologicalProcess adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae. go-plus.json adaptation to pheromone during conjugation with cellular fusion|adaptation of signalling pathway by response to pheromone involved in conjugation with cellular fusion|desensitization to pheromone during conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0000754 GO:0000753 biolink:BiologicalProcess cell morphogenesis involved in conjugation with cellular fusion The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion. go-plus.json shmooing|shmoo orientation http://purl.obolibrary.org/obo/GO_0000753 GO:0000752 biolink:BiologicalProcess agglutination involved in conjugation with cellular fusion The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae. go-plus.json agglutination|cell-cell adhesion during conjugation with cellular fusion|cell-cell adhesion during mating http://purl.obolibrary.org/obo/GO_0000752 GO:0000751 biolink:BiologicalProcess mitotic cell cycle G1 arrest in response to pheromone The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae. go-plus.json cell cycle arrest in response to pheromone http://purl.obolibrary.org/obo/GO_0000751 CHEBI:133927 biolink:ChemicalSubstance glycolaldehyde phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133927 chebi_ph7_3 CHEBI:133929 biolink:ChemicalSubstance 3,4-bis(7-chloroindol-3-yl)-2,5-diiminiohexanedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133929 chebi_ph7_3 CHEBI:24031 biolink:ChemicalSubstance ferulic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_24031 CHEBI:133928 biolink:ChemicalSubstance 2,5-diiminio-3,4-bis(indol-3-yl)hexanedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133928 chebi_ph7_3 CHEBI:38679 biolink:ChemicalSubstance fluorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_38679 CHEBI:63606 biolink:ChemicalSubstance (6S)-5-formyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_63606 GO:0000758 biolink:BiologicalProcess agglutination involved in conjugation with mutual genetic exchange The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism. go-plus.json sexual flocculation|agglutination involved in conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000758 GO:0000757 biolink:BiologicalProcess obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion. go-plus.json signal transduction involved in conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000757 CHEBI:38670 biolink:ChemicalSubstance pyrrolopyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38670 GO:0000756 biolink:BiologicalProcess response to pheromone regulating conjugation with mutual genetic exchange Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion. go-plus.json response to pheromone triggering conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000756 GO:0000755 biolink:BiologicalProcess cytogamy During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae. go-plus.json zygote formation http://purl.obolibrary.org/obo/GO_0000755 CHEBI:38674 biolink:ChemicalSubstance chromenemonocarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38674 CHEBI:38672 biolink:ChemicalSubstance flavans go-plus.json http://purl.obolibrary.org/obo/CHEBI_38672 chebi_ph7_3 GO:0000759 biolink:BiologicalProcess obsolete cell morphogenesis involved in conjugation with mutual genetic exchange OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion. go-plus.json cellular morphogenesis involved in conjugation without cellular fusion http://purl.obolibrary.org/obo/GO_0000759 GO:0097631 biolink:CellularComponent integral component of omegasome membrane The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json omegasome integral membrane protein|integral to omegasome membrane http://purl.obolibrary.org/obo/GO_0097631 GO:0097630 biolink:CellularComponent intrinsic component of omegasome membrane The component of the omegasome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to omegasome membrane http://purl.obolibrary.org/obo/GO_0097630 GO:1903869 biolink:BiologicalProcess negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity. go-plus.json down-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|downregulation of 5,10-CH(2)-H(4)folate reductase activity|down regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|downregulation of N5,N10-methylenetetrahydrofolate reductase activity|downregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of 5,10-methylenetetrahydropteroylglutamate reductase activity|down regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|inhibition of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|inhibition of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down regulation of MetF|down-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|down regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of 5,10-CH2-H4folate reductase activity|downregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|inhibition of 5,10-CH(2)-H(4)folate reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down regulation of 5,10-CH2-H4folate reductase activity|inhibition of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|inhibition of MetF|negative regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|negative regulation of methylenetetrahydrofolate reductase (NADPH2)|down-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|negative regulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of 5,10-CH2-H4folate reductase activity|downregulation of methylenetetrahydrofolate reductase [NAD(P)H]|negative regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|downregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|down-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|negative regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|negative regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|downregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of N5,N10-methylenetetrahydrofolate reductase activity|inhibition of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase (NADPH(2)) activity|downregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:NAD oxidoreductase activity|down-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|negative regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|downregulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of MetF|down regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|down-regulation of MetF|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|downregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|inhibition of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of N5,10-methylenetetrahydrofolate reductase activity|inhibition of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down-regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down regulation of methylenetetrahydrofolate reductase (NADPH2)|inhibition of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|inhibition of N5,10-methylenetetrahydrofolate reductase activity|negative regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|down-regulation of 5,10-CH2-H4folate reductase activity|down regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|inhibition of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of 5,10-CH2-H4folate reductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|inhibition of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|down regulation of N5,N10-methylenetetrahydrofolate reductase activity|down regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of MetF|inhibition of methylenetetrahydrofolate reductase [NAD(P)H] http://purl.obolibrary.org/obo/GO_1903869 GO:1903868 biolink:BiologicalProcess regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity. go-plus.json regulation of MetF|regulation of 5,10-CH(2)-H(4)folate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|regulation of 5,10-CH2-H4folate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|regulation of methylenetetrahydrofolate reductase [NAD(P)H]|regulation of 5,10-methylenetetrahydrofolic acid reductase activity|regulation of methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|regulation of MTHFR activity|regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|regulation of N(5),N(10)-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate reductase (NADPH2)|regulation of N5,10-methylenetetrahydrofolate reductase activity|regulation of N(5,10)-methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|regulation of 5,10-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|regulation of methylenetetrahydrofolic acid reductase activity|regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|regulation of N5,N10-methylenetetrahydrofolate reductase activity http://purl.obolibrary.org/obo/GO_1903868 GO:1903867 biolink:BiologicalProcess extraembryonic membrane development The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_1903867 GO:1903866 biolink:BiologicalProcess palisade mesophyll development The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure. go-plus.json palisade parenchyma development http://purl.obolibrary.org/obo/GO_1903866 GO:1903865 biolink:CellularComponent sigma factor antagonist complex A protein complex which is capable of sigma factor antagonist activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903865 GO:1903864 biolink:BiologicalProcess P granule disassembly The disaggregation of a P granule into its constituent components. go-plus.json polar granule disassembly|germline granule disassembly http://purl.obolibrary.org/obo/GO_1903864 GO:1903863 biolink:BiologicalProcess P granule assembly The aggregation, arrangement and bonding together of a set of components to form a P granule. go-plus.json germline granule formation|polar granule assembly|polar granule formation|germline granule assembly|P granule formation http://purl.obolibrary.org/obo/GO_1903863 GO:1903862 biolink:BiologicalProcess positive regulation of oxidative phosphorylation Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation. go-plus.json up regulation of oxidative phosphorylation|activation of oxidative phosphorylation|up regulation of respiratory-chain phosphorylation|positive regulation of respiratory-chain phosphorylation|activation of respiratory-chain phosphorylation|up-regulation of oxidative phosphorylation|up-regulation of respiratory-chain phosphorylation|upregulation of oxidative phosphorylation|upregulation of respiratory-chain phosphorylation http://purl.obolibrary.org/obo/GO_1903862 GO:1903861 biolink:BiologicalProcess positive regulation of dendrite extension Any process that activates or increases the frequency, rate or extent of dendrite extension. go-plus.json upregulation of dendrite extension|activation of dendrite extension|up-regulation of dendrite extension|up regulation of dendrite extension http://purl.obolibrary.org/obo/GO_1903861 GO:1903860 biolink:BiologicalProcess negative regulation of dendrite extension Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension. go-plus.json downregulation of dendrite extension|up-regulation of dendrite retraction|down regulation of dendrite extension|inhibition of dendrite extension|up regulation of dendrite retraction|down-regulation of dendrite extension http://purl.obolibrary.org/obo/GO_1903860 GO:0009099 biolink:BiologicalProcess valine biosynthetic process The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid. MetaCyc:VALSYN-PWY go-plus.json valine anabolism|valine synthesis|valine formation|valine biosynthesis http://purl.obolibrary.org/obo/GO_0009099 GO:1903870 biolink:BiologicalProcess positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity. go-plus.json positive regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|activation of 5,10-methylenetetrahydropteroylglutamate reductase activity|positive regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|upregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|positive regulation of MetF|upregulation of N5,N10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|up-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|upregulation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of MetF|positive regulation of 5,10-CH(2)-H(4)folate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of 5,10-CH(2)-H(4)folate reductase activity|activation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|upregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|positive regulation of 5,10-CH2-H4folate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up regulation of 5,10-CH2-H4folate reductase activity|up-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of methylenetetrahydrofolate reductase [NAD(P)H]|up-regulation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up-regulation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of N5,N10-methylenetetrahydrofolate reductase activity|up regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|activation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of MetF|up-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|activation of methylenetetrahydrofolate reductase (NAD(P)H) activity|activation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of methylenetetrahydrofolate reductase (NADPH(2)) activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|positive regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of N5,N10-methylenetetrahydrofolate reductase activity|positive regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|positive regulation of N5,N10-methylenetetrahydrofolate reductase activity|activation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|positive regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|upregulation of 5,10-CH(2)-H(4)folate reductase activity|up-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|up regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|upregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5,10-CH2-H4folate reductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|activation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|activation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of methylenetetrahydrofolate reductase [NAD(P)H]|up regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|positive regulation of N5,10-methylenetetrahydrofolate reductase activity|up-regulation of MetF|positive regulation of methylenetetrahydrofolate reductase (NADPH2)|activation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|positive regulation of methylenetetrahydrofolate reductase [NAD(P)H]|up-regulation of 5,10-CH(2)-H(4)folate reductase activity|up regulation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|activation of 5,10-CH(2)-H(4)folate reductase activity|up-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|positive regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up-regulation of N5,N10-methylenetetrahydrofolate reductase activity|up-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|positive regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up-regulation of 5,10-CH2-H4folate reductase activity|activation of methylenetetrahydrofolate reductase [NAD(P)H]|activation of MetF|up regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|activation of 5,10-CH2-H4folate reductase activity http://purl.obolibrary.org/obo/GO_1903870 GO:0010087 biolink:BiologicalProcess phloem or xylem histogenesis The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana. go-plus.json vascular tissue histogenesis|vascular tissue development http://purl.obolibrary.org/obo/GO_0010087 GO:0034054 biolink:BiologicalProcess suppression by symbiont of host defense-related programmed cell death Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json suppression of HR|negative regulation by symbiont of host defense-related programmed cell death|inhibition of host defense-related PCD|suppression by symbiont of host defense-related programmed cell death|negative regulation by symbiont of host defense-related PCD|down-regulation by symbiont of host defense-related programmed cell death|inhibition of HR|negative regulation by symbiont of plant hypersensitive response|downregulation by symbiont of host defense-related programmed cell death|inhibition by symbiont of host defense-related PCD|down regulation by symbiont of host defense-related programmed cell death|inhibition by symbiont of host defense-related programmed cell death|negative regulation by symbiont of plant HR|inhibition of hypersensitive response http://purl.obolibrary.org/obo/GO_0034054 GO:0034053 biolink:BiologicalProcess modulation by symbiont of host defense-related programmed cell death Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host defense-related PCD|modulation by symbiont of host hypersensitive response|modulation by symbiont of plant HR|modulation by symbiont of host HR|modulation by symbiont of plant hypersensitive response http://purl.obolibrary.org/obo/GO_0034053 GO:0010086 biolink:BiologicalProcess embryonic root morphogenesis The process in which the anatomical structures of the embryonic root are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0010086 GO:0010089 biolink:BiologicalProcess xylem development The formation of the principal water-conducting tissue of a vascular plant. go-plus.json xylem histogenesis http://purl.obolibrary.org/obo/GO_0010089 GO:0034052 biolink:BiologicalProcess positive regulation of plant-type hypersensitive response Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant. go-plus.json up regulation of plant-type hypersensitive response|positive regulation of plant hypersensitive response|positive regulation of HR|positive regulation of HR-PCD|upregulation of plant-type hypersensitive response|stimulation of plant-type hypersensitive response|activation of plant-type hypersensitive response|up-regulation of plant-type hypersensitive response http://purl.obolibrary.org/obo/GO_0034052 GO:0010088 biolink:BiologicalProcess phloem development The formation of the principal food-conducting tissue of a vascular plant. go-plus.json phloem histogenesis http://purl.obolibrary.org/obo/GO_0010088 GO:0034051 biolink:BiologicalProcess negative regulation of plant-type hypersensitive response Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant. go-plus.json negative regulation of HR-PCD|downregulation of plant-type hypersensitive response|negative regulation of HR|down regulation of plant-type hypersensitive response|negative regulation of plant hypersensitive response|inhibition of plant-type hypersensitive response|down-regulation of plant-type hypersensitive response http://purl.obolibrary.org/obo/GO_0034051 GO:0034050 biolink:BiologicalProcess programmed cell death induced by symbiont Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules. go-plus.json 'host programmed cell death induced by symbiont' http://purl.obolibrary.org/obo/GO_0034050 GO:0097637 biolink:CellularComponent integral component of autophagosome membrane The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json autophagic vacuole integral membrane protein|integral to autophagic vacuole membrane|integral component of autophagic vacuole membrane http://purl.obolibrary.org/obo/GO_0097637 GO:0097636 biolink:CellularComponent intrinsic component of autophagosome membrane The component of the autophagosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to autophagic vacuole membrane|intrinsic component of autophagic vacuole membrane http://purl.obolibrary.org/obo/GO_0097636 GO:0097639 biolink:BiologicalProcess L-lysine import across plasma membrane The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-lysine import into cell http://purl.obolibrary.org/obo/GO_0097639 GO:0010081 biolink:BiologicalProcess regulation of inflorescence meristem growth Any process involved in maintaining the size and shape of an inflorescence meristem. go-plus.json regulation of inflorescence meristem size http://purl.obolibrary.org/obo/GO_0010081 GO:0010080 biolink:BiologicalProcess regulation of floral meristem growth Any process involved in maintaining the size and shape of a floral meristem. go-plus.json regulation of floral meristem size http://purl.obolibrary.org/obo/GO_0010080 GO:0097638 biolink:BiologicalProcess L-arginine import across plasma membrane The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-arginine import into cell|arginine import http://purl.obolibrary.org/obo/GO_0097638 GO:0034059 biolink:BiologicalProcess response to anoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%. go-plus.json response to anoxic stress http://purl.obolibrary.org/obo/GO_0034059 GO:0034058 biolink:BiologicalProcess endosomal vesicle fusion The homotypic fusion of endocytic vesicles to form or add to an early endosome. go-plus.json endosome vesicle fusion http://purl.obolibrary.org/obo/GO_0034058 GO:0010083 biolink:BiologicalProcess regulation of vegetative meristem growth Any process involved in maintaining the size and shape of a vegetative meristem. go-plus.json regulation of vegetative meristem size http://purl.obolibrary.org/obo/GO_0010083 GO:0097633 biolink:CellularComponent intrinsic component of phagophore assembly site membrane The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json intrinsic to phagophore assembly site membrane http://purl.obolibrary.org/obo/GO_0097633 GO:0097632 biolink:CellularComponent extrinsic component of phagophore assembly site membrane The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic component of pre-autophagosomal structure membrane|extrinsic to phagophore assembly site membrane|phagophore assembly site peripheral membrane http://purl.obolibrary.org/obo/GO_0097632 GO:0034057 biolink:MolecularActivity RNA strand-exchange activity Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity. go-plus.json http://purl.obolibrary.org/obo/GO_0034057 GO:0010082 biolink:BiologicalProcess regulation of root meristem growth Any process involved in maintaining the size and shape of a root meristem. go-plus.json regulation of root meristem size http://purl.obolibrary.org/obo/GO_0010082 GO:0097635 biolink:CellularComponent extrinsic component of autophagosome membrane The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json autophagic vacuole peripheral membrane|extrinsic to autophagic vacuole membrane|extrinsic component of autophagic vacuole membrane http://purl.obolibrary.org/obo/GO_0097635 GO:0010085 biolink:BiologicalProcess polarity specification of proximal/distal axis Any process resulting in the establishment of polarity along the proximal/distal axis. go-plus.json http://purl.obolibrary.org/obo/GO_0010085 GO:0034056 biolink:MolecularActivity estrogen response element binding Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen. go-plus.json ERE binding http://purl.obolibrary.org/obo/GO_0034056 NCBITaxon:1699524 biolink:OrganismalEntity Eucalypteae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1699524 GO:0097634 biolink:CellularComponent integral component of phagophore assembly site membrane The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json phagophore assembly site integral membrane protein|integral to phagophore assembly site membrane http://purl.obolibrary.org/obo/GO_0097634 GO:0034055 biolink:BiologicalProcess effector-mediated induction of programmed cell death in host A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json stimulation by symbiont of host defense-related programmed cell death|up-regulation by symbiont of host defense-related programmed cell death|activation by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related PCD|enhancement by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related programmed cell death|up regulation by symbiont of host defense-related programmed cell death|upregulation by symbiont of host defense-related programmed cell death http://purl.obolibrary.org/obo/GO_0034055 GO:0010084 biolink:BiologicalProcess specification of animal organ axis polarity The process in which the polarity of an animal organ axis is specified. go-plus.json http://purl.obolibrary.org/obo/GO_0010084 GO:0097640 biolink:BiologicalProcess L-ornithine import across plasma membrane The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-ornithine import into cell http://purl.obolibrary.org/obo/GO_0097640 GO:0097642 biolink:MolecularActivity calcitonin family receptor activity Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0097642 GO:0097641 biolink:MolecularActivity alpha-ketoglutarate-dependent xanthine dioxygenase activity Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate. RHEA:43120 go-plus.json alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity|2-oxoglutarate-dependent xanthine dioxygenase activity|alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity http://purl.obolibrary.org/obo/GO_0097641 GO:1903879 biolink:MolecularActivity 11beta-hydroxyprogesterone binding Binding to 11beta-hydroxyprogesterone. go-plus.json http://purl.obolibrary.org/obo/GO_1903879 GO:1903878 biolink:MolecularActivity 11-deoxycorticosterone binding Binding to 11-deoxycorticosterone. go-plus.json http://purl.obolibrary.org/obo/GO_1903878 GO:1903877 biolink:MolecularActivity 21-deoxycortisol binding Binding to 21-deoxycortisol. go-plus.json http://purl.obolibrary.org/obo/GO_1903877 GO:1903876 biolink:MolecularActivity 11-deoxycortisol binding Binding to 11-deoxycortisol. go-plus.json http://purl.obolibrary.org/obo/GO_1903876 GO:1903875 biolink:MolecularActivity corticosterone binding Binding to corticosterone. go-plus.json http://purl.obolibrary.org/obo/GO_1903875 GO:1903874 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903874 GO:1903873 biolink:BiologicalProcess negative regulation of DNA recombinase mediator complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly. go-plus.json down regulation of DNA recombinase mediator complex assembly|down-regulation of DNA recombinase mediator complex formation|negative regulation of DNA recombinase mediator complex formation|downregulation of DNA recombinase mediator complex assembly|downregulation of DNA recombinase mediator complex formation|down-regulation of DNA recombinase mediator complex assembly|down regulation of DNA recombinase mediator complex formation|inhibition of DNA recombinase mediator complex formation|inhibition of DNA recombinase mediator complex assembly http://purl.obolibrary.org/obo/GO_1903873 GO:1903872 biolink:BiologicalProcess regulation of DNA recombinase mediator complex assembly Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly. go-plus.json regulation of DNA recombinase mediator complex formation http://purl.obolibrary.org/obo/GO_1903872 GO:1903871 biolink:BiologicalProcess DNA recombinase mediator complex assembly The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex. go-plus.json DNA recombinase mediator complex formation http://purl.obolibrary.org/obo/GO_1903871 GO:0034043 biolink:MolecularActivity 5-hydroxymethyluracil DNA N-glycosylase activity Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. go-plus.json 5-hmU DNA N-glycosylase activity http://purl.obolibrary.org/obo/GO_0034043 GO:0010098 biolink:BiologicalProcess suspensor development The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm. go-plus.json http://purl.obolibrary.org/obo/GO_0010098 GO:1903881 biolink:BiologicalProcess regulation of interleukin-17-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway. go-plus.json regulation of IL-17-mediated signalling pathway|regulation of IL-17-mediated signaling pathway|regulation of interleukin-17-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1903881 GO:0034042 biolink:MolecularActivity 5-formyluracil DNA N-glycosylase activity Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. go-plus.json 5-foU DNA N-glycosylase activity http://purl.obolibrary.org/obo/GO_0034042 GO:1903880 biolink:MolecularActivity 17alpha-hydroxyprogesterone binding Binding to 17alpha-hydroxyprogesterone. go-plus.json http://purl.obolibrary.org/obo/GO_1903880 GO:0010097 biolink:BiologicalProcess specification of stamen identity The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010097 GO:0034041 biolink:MolecularActivity ABC-type sterol transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out). go-plus.json ATPase-coupled sterol transmembrane transporter activity|sterol-transporting ATPase activity|ATP-coupled sterol transmembrane transporter activity|ATP-dependent sterol transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034041 GO:0010099 biolink:BiologicalProcess regulation of photomorphogenesis Any process that modulates the rate or extent of photomorphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0010099 GO:0034040 biolink:MolecularActivity ATPase-coupled lipid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out). go-plus.json lipid-transporting ATPase activity|ATP-dependent lipid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034040 GO:0097648 biolink:CellularComponent G protein-coupled receptor complex A protein complex that contains G protein-coupled receptors. go-plus.json G-protein coupled receptor complex http://purl.obolibrary.org/obo/GO_0097648 GO:0010090 biolink:BiologicalProcess trichome morphogenesis The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana. go-plus.json trichome cell morphogenesis during differentiation http://purl.obolibrary.org/obo/GO_0010090 GO:0097647 biolink:BiologicalProcess amylin receptor signaling pathway A series of molecular signals initiated by an extracellular amylin combining with a dimeric amylin receptor on the surface of the target cell. go-plus.json amilyn receptor signalling pathway http://purl.obolibrary.org/obo/GO_0097647 GO:0010092 biolink:BiologicalProcess specification of animal organ identity The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010092 GO:0034049 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034049 GO:0097649 biolink:CellularComponent A axonemal microtubule A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule. go-plus.json A tubule http://purl.obolibrary.org/obo/GO_0097649 GO:0010091 biolink:BiologicalProcess trichome branching Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0010091 GO:0034048 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034048 GO:0097644 biolink:MolecularActivity calcitonin family binding Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)). go-plus.json http://purl.obolibrary.org/obo/GO_0097644 GO:0010094 biolink:BiologicalProcess specification of carpel identity The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010094 GO:0034047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034047 GO:0097643 biolink:MolecularActivity amylin receptor activity Combining with amylin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0097643 GO:0034046 biolink:MolecularActivity poly(G) binding Binding to a sequence of guanine residues in an RNA molecule. go-plus.json poly(rG) binding|poly(G) binding, within an RNA molecule http://purl.obolibrary.org/obo/GO_0034046 GO:0010093 biolink:BiologicalProcess specification of floral organ identity The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010093 GO:0097646 biolink:BiologicalProcess calcitonin family receptor signaling pathway A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. go-plus.json calcitonin family receptor signalling pathway http://purl.obolibrary.org/obo/GO_0097646 GO:0034045 biolink:CellularComponent phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site. go-plus.json PAS membrane|phagophore|pre-autophagosomal structure membrane|isolation membrane http://purl.obolibrary.org/obo/GO_0034045 GO:0010096 biolink:BiologicalProcess specification of sepal identity The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010096 GO:0097645 biolink:MolecularActivity amylin binding Binding to amylin. go-plus.json http://purl.obolibrary.org/obo/GO_0097645 GO:0010095 biolink:BiologicalProcess specification of petal identity The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0010095 GO:0034044 biolink:CellularComponent exomer complex A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues. go-plus.json http://purl.obolibrary.org/obo/GO_0034044 GO:1903889 biolink:BiologicalProcess negative regulation of plant epidermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation. go-plus.json down-regulation of plant epidermal cell differentiation|downregulation of plant epidermal cell differentiation|down regulation of plant epidermal cell differentiation|inhibition of plant epidermal cell differentiation http://purl.obolibrary.org/obo/GO_1903889 GO:1903888 biolink:BiologicalProcess regulation of plant epidermal cell differentiation Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1903888 GO:1903887 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903887 GO:1903886 biolink:BiologicalProcess positive regulation of chemokine (C-C motif) ligand 20 production Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production. go-plus.json activation of CCL20 production|up-regulation of chemokine (C-C motif) ligand 20 production|activation of chemokine (C-C motif) ligand 20 production|upregulation of CCL-20 production|upregulation of C-C motif chemokine 20 production|positive regulation of CCL20 production|up regulation of CCL20 production|up regulation of C-C motif chemokine 20 production|up regulation of CCL-20 production|positive regulation of CCL-20 production|up regulation of chemokine (C-C motif) ligand 20 production|activation of C-C motif chemokine 20 production|positive regulation of C-C motif chemokine 20 production|activation of CCL-20 production|upregulation of CCL20 production|upregulation of chemokine (C-C motif) ligand 20 production|up-regulation of CCL-20 production|up-regulation of C-C motif chemokine 20 production|up-regulation of CCL20 production http://purl.obolibrary.org/obo/GO_1903886 GO:1903885 biolink:BiologicalProcess negative regulation of chemokine (C-C motif) ligand 20 production Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production. go-plus.json down-regulation of CCL20 production|negative regulation of CCL20 production|down regulation of CCL-20 production|down regulation of C-C motif chemokine 20 production|down-regulation of chemokine (C-C motif) ligand 20 production|downregulation of CCL-20 production|downregulation of C-C motif chemokine 20 production|downregulation of CCL20 production|down regulation of CCL20 production|inhibition of CCL20 production|downregulation of chemokine (C-C motif) ligand 20 production|down-regulation of C-C motif chemokine 20 production|negative regulation of CCL-20 production|down-regulation of CCL-20 production|negative regulation of C-C motif chemokine 20 production|down regulation of chemokine (C-C motif) ligand 20 production|inhibition of chemokine (C-C motif) ligand 20 production|inhibition of CCL-20 production|inhibition of C-C motif chemokine 20 production http://purl.obolibrary.org/obo/GO_1903885 GO:1903884 biolink:BiologicalProcess regulation of chemokine (C-C motif) ligand 20 production Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production. go-plus.json regulation of C-C motif chemokine 20 production|regulation of CCL-20 production|regulation of CCL20 production http://purl.obolibrary.org/obo/GO_1903884 GO:0009079 biolink:BiologicalProcess pyruvate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine. go-plus.json pyruvate family amino acid anabolism|pyruvate family amino acid synthesis|pyruvate family amino acid formation|pyruvate family amino acid biosynthesis http://purl.obolibrary.org/obo/GO_0009079 GO:0009078 biolink:BiologicalProcess pyruvate family amino acid metabolic process The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine. go-plus.json pyruvate family amino acid metabolism http://purl.obolibrary.org/obo/GO_0009078 GO:1903883 biolink:BiologicalProcess positive regulation of interleukin-17-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway. go-plus.json upregulation of interleukin-17-mediated signaling pathway|upregulation of IL-17-mediated signalling pathway|positive regulation of IL-17-mediated signaling pathway|positive regulation of interleukin-17-mediated signalling pathway|up regulation of IL-17-mediated signaling pathway|up regulation of interleukin-17-mediated signalling pathway|up regulation of interleukin-17-mediated signaling pathway|activation of interleukin-17-mediated signaling pathway|up regulation of IL-17-mediated signalling pathway|activation of IL-17-mediated signalling pathway|positive regulation of IL-17-mediated signalling pathway|upregulation of IL-17-mediated signaling pathway|upregulation of interleukin-17-mediated signalling pathway|up-regulation of interleukin-17-mediated signaling pathway|up-regulation of IL-17-mediated signalling pathway|activation of IL-17-mediated signaling pathway|up-regulation of IL-17-mediated signaling pathway|up-regulation of interleukin-17-mediated signalling pathway|activation of interleukin-17-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1903883 GO:0009077 biolink:BiologicalProcess obsolete histidine family amino acid catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family. go-plus.json histidine family amino acid degradation|histidine family amino acid breakdown|histidine family amino acid catabolic process|histidine family amino acid catabolism http://purl.obolibrary.org/obo/GO_0009077 GO:1903882 biolink:BiologicalProcess negative regulation of interleukin-17-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway. go-plus.json negative regulation of IL-17-mediated signaling pathway|down-regulation of IL-17-mediated signaling pathway|down-regulation of interleukin-17-mediated signalling pathway|negative regulation of interleukin-17-mediated signalling pathway|down regulation of interleukin-17-mediated signaling pathway|down regulation of IL-17-mediated signalling pathway|downregulation of interleukin-17-mediated signaling pathway|downregulation of IL-17-mediated signalling pathway|downregulation of IL-17-mediated signaling pathway|downregulation of interleukin-17-mediated signalling pathway|down regulation of IL-17-mediated signaling pathway|down regulation of interleukin-17-mediated signalling pathway|down-regulation of interleukin-17-mediated signaling pathway|inhibition of IL-17-mediated signaling pathway|down-regulation of IL-17-mediated signalling pathway|negative regulation of IL-17-mediated signalling pathway|inhibition of interleukin-17-mediated signalling pathway|inhibition of interleukin-17-mediated signaling pathway|inhibition of IL-17-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1903882 GO:1903892 biolink:BiologicalProcess negative regulation of ATF6-mediated unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response. go-plus.json inhibition of UPR signaling by ATF6 stress sensor|inhibition of ATF6 branch of UPR|negative regulation of ATF6-alpha UPR branch|down regulation of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6-alpha UPR branch|inhibition of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6 signaling in response to endoplasmic reticulum stress|negative regulation of ATF6 signaling in response to endoplasmic reticulum stress|inhibition of ATF6-mediated unfolded protein response|negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down-regulation of ATF6-beta UPR branch|negative regulation of ATF6-beta UPR branch|downregulation of ATF6 signaling in response to endoplasmic reticulum stress|down regulation of UPR signaling by ATF6 stress sensor|inhibition of ATF6-alpha UPR branch|inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of ATF6 signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by ATF6 stress sensor|down-regulation of ATF6 branch of UPR|negative regulation of ATF6 branch of UPR|down regulation of ATF6-mediated unfolded protein response|downregulation of ATF6-beta UPR branch|down regulation of ATF6-alpha UPR branch|down-regulation of activating transcription factor 6 signaling in unfolded protein response|negative regulation of activating transcription factor 6 signaling in unfolded protein response|downregulation of ATF6-mediated unfolded protein response|inhibition of ATF6 signaling in response to endoplasmic reticulum stress|down regulation of ATF6-beta UPR branch|downregulation of ATF6-alpha UPR branch|down-regulation of UPR signaling by ATF6 stress sensor|negative regulation of UPR signaling by ATF6 stress sensor|down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|downregulation of ATF6 branch of UPR|downregulation of activating transcription factor 6 signaling in unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of ATF6 branch of UPR|inhibition of ATF6-beta UPR branch|down-regulation of ATF6-mediated unfolded protein response http://purl.obolibrary.org/obo/GO_1903892 GO:0009087 biolink:BiologicalProcess methionine catabolic process The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. UM-BBD_pathwayID:met go-plus.json methionine catabolism|methionine degradation|methionine breakdown http://purl.obolibrary.org/obo/GO_0009087 GO:0010065 biolink:BiologicalProcess primary meristem tissue development The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium. go-plus.json primary meristem histogenesis http://purl.obolibrary.org/obo/GO_0010065 GO:0034032 biolink:BiologicalProcess purine nucleoside bisphosphate metabolic process The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json purine nucleoside bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0034032 GO:1903891 biolink:BiologicalProcess regulation of ATF6-mediated unfolded protein response Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response. go-plus.json regulation of ATF6 signaling in response to endoplasmic reticulum stress|regulation of UPR signaling by ATF6 stress sensor|regulation of ATF6 signal transduction pathway|regulation of ATF6-beta UPR branch|regulation of ATF6-alpha UPR branch|regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|regulation of ATF6 branch of UPR|regulation of activating transcription factor 6 signaling in unfolded protein response http://purl.obolibrary.org/obo/GO_1903891 GO:0009086 biolink:BiologicalProcess methionine biosynthetic process The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. go-plus.json methionine biosynthesis|methionine anabolism|methionine synthesis|methionine formation http://purl.obolibrary.org/obo/GO_0009086 GO:0010064 biolink:BiologicalProcess embryonic shoot morphogenesis The process in which the anatomical structures of embryonic shoot are generated and organized. go-plus.json primary shoot system morphogenesis http://purl.obolibrary.org/obo/GO_0010064 GO:0034031 biolink:BiologicalProcess ribonucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json ribonucleoside bisphosphate degradation|ribonucleoside bisphosphate breakdown|ribonucleoside bisphosphate catabolism http://purl.obolibrary.org/obo/GO_0034031 GO:1903890 biolink:BiologicalProcess positive regulation of plant epidermal cell differentiation Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation. go-plus.json up-regulation of plant epidermal cell differentiation|activation of plant epidermal cell differentiation|up regulation of plant epidermal cell differentiation|upregulation of plant epidermal cell differentiation http://purl.obolibrary.org/obo/GO_1903890 GO:0034030 biolink:BiologicalProcess ribonucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json ribonucleoside bisphosphate anabolism|ribonucleoside bisphosphate synthesis|ribonucleoside bisphosphate biosynthesis|ribonucleoside bisphosphate formation http://purl.obolibrary.org/obo/GO_0034030 GO:0009085 biolink:BiologicalProcess lysine biosynthetic process The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid. MetaCyc:PWY-5097 go-plus.json lysine synthesis|lysine formation|lysine anabolism|lysine biosynthesis http://purl.obolibrary.org/obo/GO_0009085 GO:0010067 biolink:BiologicalProcess procambium histogenesis The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0010067 GO:0009084 biolink:BiologicalProcess glutamine family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. go-plus.json glutamine family amino acid anabolism|glutamine family amino acid biosynthesis|glutamine family amino acid synthesis|glutamine family amino acid formation http://purl.obolibrary.org/obo/GO_0009084 GO:0010066 biolink:BiologicalProcess ground meristem histogenesis The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0010066 GO:0009083 biolink:BiologicalProcess branched-chain amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. go-plus.json branched chain family amino acid catabolic process|branched chain family amino acid degradation|branched chain family amino acid breakdown|branched chain family amino acid catabolism http://purl.obolibrary.org/obo/GO_0009083 GO:0097619 biolink:CellularComponent PTEX complex A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components. go-plus.json Plasmodium translocon of exported proteins http://purl.obolibrary.org/obo/GO_0097619 GO:0010069 biolink:BiologicalProcess zygote asymmetric cytokinesis in embryo sac The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana. go-plus.json http://purl.obolibrary.org/obo/GO_0010069 GO:0009082 biolink:BiologicalProcess branched-chain amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. go-plus.json branched chain family amino acid biosynthesis|branched chain family amino acid formation|branched chain family amino acid biosynthetic process|branched chain family amino acid anabolism|branched chain family amino acid synthesis http://purl.obolibrary.org/obo/GO_0009082 GO:0097618 biolink:CellularComponent dinoflagellate sulcal notch A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed. go-plus.json sulcal notch|dinoflagellate sulcus notch http://purl.obolibrary.org/obo/GO_0097618 GO:0010068 biolink:BiologicalProcess protoderm histogenesis The formation of the primary meristem or meristematic tissue that gives rise to the epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0010068 GO:0009081 biolink:BiologicalProcess branched-chain amino acid metabolic process The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. go-plus.json branched chain family amino acid metabolism http://purl.obolibrary.org/obo/GO_0009081 GO:0009080 biolink:BiologicalProcess pyruvate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine. go-plus.json pyruvate family amino acid catabolism|pyruvate family amino acid degradation|pyruvate family amino acid breakdown http://purl.obolibrary.org/obo/GO_0009080 SO:0000613 biolink:SequenceFeature bacterial_RNApol_promoter A DNA sequence to which bacterial RNA polymerase binds, to begin transcription. go-plus.json bacterial RNApol promoter http://purl.obolibrary.org/obo/SO_0000613 GO:0097615 biolink:BiologicalProcess modulation by host of symbiont type IV pilus-dependent motility The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by host of bacterial type IV pilus-dependent motility http://purl.obolibrary.org/obo/GO_0097615 GO:0097614 biolink:CellularComponent dinoflagellate hypocone The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum. go-plus.json hypocone|hyposome|hypotheca http://purl.obolibrary.org/obo/GO_0097614 GO:0034039 biolink:MolecularActivity 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. go-plus.json 8-oxoG DNA N-glycosylase activity http://purl.obolibrary.org/obo/GO_0034039 GO:0034038 biolink:MolecularActivity deoxyhypusine synthase activity Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+. RHEA:33299|MetaCyc:2.5.1.46-RXN|Reactome:R-HSA-204617|Reactome:R-HSA-204647|EC:2.5.1.46 go-plus.json eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|eIF-5A-deoxyhypusine synthase activity http://purl.obolibrary.org/obo/GO_0034038 GO:0097617 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097617 GO:0097616 biolink:BiologicalProcess positive regulation by host of symbiont type IV pilus-dependent motility Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by host of bacterial type IV pilus-dependent motility http://purl.obolibrary.org/obo/GO_0097616 GO:0034037 biolink:BiologicalProcess purine ribonucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json purine ribonucleoside bisphosphate catabolism|purine ribonucleoside bisphosphate degradation|purine ribonucleoside bisphosphate breakdown http://purl.obolibrary.org/obo/GO_0034037 GO:0097611 biolink:CellularComponent dinoflagellate cingulum A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it. go-plus.json cingulum|transverse groove|girdle http://purl.obolibrary.org/obo/GO_0097611 GO:0034036 biolink:BiologicalProcess purine ribonucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json purine ribonucleoside bisphosphate anabolism|purine ribonucleoside bisphosphate synthesis|purine ribonucleoside bisphosphate formation|purine ribonucleoside bisphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0034036 GO:0010061 biolink:BiologicalProcess regulation of trichoblast fate specification Any process that modulates trichoblast fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0010061 GO:0097610 biolink:CellularComponent cell surface furrow A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates. go-plus.json cell surface groove|groove|furrow http://purl.obolibrary.org/obo/GO_0097610 GO:0010060 biolink:BiologicalProcess negative regulation of atrichoblast fate specification Any process that suppresses atrichoblast fate specification. go-plus.json down-regulation of atrichoblast fate|inhibition of atrichoblast fate|down regulation of atrichoblast fate|downregulation of atrichoblast fate http://purl.obolibrary.org/obo/GO_0010060 GO:0034035 biolink:BiologicalProcess purine ribonucleoside bisphosphate metabolic process The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json purine ribonucleoside bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0034035 GO:0034034 biolink:BiologicalProcess purine nucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json purine nucleoside bisphosphate catabolism|purine nucleoside bisphosphate degradation|purine nucleoside bisphosphate breakdown http://purl.obolibrary.org/obo/GO_0034034 GO:0010063 biolink:BiologicalProcess positive regulation of trichoblast fate specification Any process that induces or promotes trichoblast fate specification. go-plus.json stimulation of trichoblast fate|up-regulation of trichoblast fate|activation of trichoblast fate|up regulation of trichoblast fate|upregulation of trichoblast fate http://purl.obolibrary.org/obo/GO_0010063 GO:0097613 biolink:CellularComponent dinoflagellate epicone The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum. go-plus.json epicone|episome|epitheca http://purl.obolibrary.org/obo/GO_0097613 GO:0097612 biolink:CellularComponent dinoflagellate sulcus A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell. go-plus.json longitudinal groove|sulcus|longitudinal furrow http://purl.obolibrary.org/obo/GO_0097612 GO:0010062 biolink:BiologicalProcess negative regulation of trichoblast fate specification Any process that suppresses trichoblast fate specification. go-plus.json down-regulation of trichoblast fate|downregulation of trichoblast fate|down regulation of trichoblast fate|inhibition of trichoblast fate http://purl.obolibrary.org/obo/GO_0010062 GO:0034033 biolink:BiologicalProcess purine nucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json purine nucleoside bisphosphate anabolism|purine nucleoside bisphosphate synthesis|purine nucleoside bisphosphate formation|purine nucleoside bisphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0034033 GO:0097620 biolink:MolecularActivity (R)-mandelate dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor. RHEA:43112 go-plus.json D-mandelate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0097620 PO:0025594 biolink:OntologyClass ground meristem A portion of meristem tissue (PO:0009013) that gives rise to a portion of ground tissue (PO:0025059). go-plus.json http://purl.obolibrary.org/obo/PO_0025594 GO:1903899 biolink:BiologicalProcess positive regulation of PERK-mediated unfolded protein response Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response. go-plus.json up regulation of PERK signaling in response to endoplasmic reticulum stress|upregulation of UPR signaling by PERK stress sensor|up-regulation of PERK branch of UPR|activation of PERK branch of UPR|activation of PKR-like ER kinase signal transduction|up-regulation of PKR-like ER kinase signal transduction|up-regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up regulation of PERK-mediated unfolded protein response|activation of PERK-mediated unfolded protein response|positive regulation of EIF2AK3-mediated unfolded protein response|upregulation of PERK signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by PERK stress sensor|activation of UPR signaling by PERK stress sensor|positive regulation of PERK branch of UPR|positive regulation of UPR signaling by PERK stress sensor|positive regulation of PKR-like ER kinase signal transduction|upregulation of endoplasmic reticulum unfolded protein response; PERK signaling|up regulation of PERK branch of UPR|up regulation of PKR-like ER kinase signal transduction|up-regulation of PERK signaling in response to endoplasmic reticulum stress|up-regulation of PERK-mediated unfolded protein response|up regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up-regulation of UPR signaling by PERK stress sensor|activation of PERK signaling in response to endoplasmic reticulum stress|upregulation of PERK branch of UPR|activation of endoplasmic reticulum unfolded protein response; PERK signaling|positive regulation of endoplasmic reticulum unfolded protein response; PERK signaling|upregulation of PKR-like ER kinase signal transduction|upregulation of PERK-mediated unfolded protein response|positive regulation of PERK signaling in response to endoplasmic reticulum stress http://purl.obolibrary.org/obo/GO_1903899 GO:1903898 biolink:BiologicalProcess negative regulation of PERK-mediated unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response. go-plus.json down regulation of PERK-mediated unfolded protein response|downregulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of PERK-mediated unfolded protein response|negative regulation of EIF2AK3-mediated unfolded protein response|down regulation of UPR signaling by PERK stress sensor|inhibition of endoplasmic reticulum unfolded protein response; PERK signaling|down regulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by PERK stress sensor|down-regulation of PERK branch of UPR|negative regulation of PERK branch of UPR|down-regulation of PKR-like ER kinase signal transduction|negative regulation of PKR-like ER kinase signal transduction|down-regulation of PERK-mediated unfolded protein response|inhibition of PERK signaling in response to endoplasmic reticulum stress|down regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of UPR signaling by PERK stress sensor|negative regulation of UPR signaling by PERK stress sensor|downregulation of PERK branch of UPR|inhibition of PERK-mediated unfolded protein response|downregulation of PKR-like ER kinase signal transduction|downregulation of endoplasmic reticulum unfolded protein response; PERK signaling|down regulation of PERK branch of UPR|down regulation of PKR-like ER kinase signal transduction|inhibition of UPR signaling by PERK stress sensor|inhibition of PERK branch of UPR|inhibition of PKR-like ER kinase signal transduction|negative regulation of PERK signaling in response to endoplasmic reticulum stress|down-regulation of PERK signaling in response to endoplasmic reticulum stress|negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling http://purl.obolibrary.org/obo/GO_1903898 GO:1903897 biolink:BiologicalProcess regulation of PERK-mediated unfolded protein response Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response. go-plus.json regulation of PERK signaling in response to endoplasmic reticulum stress|regulation of UPR signaling by PERK stress sensor|regulation of PERK signal transduction pathway|regulation of EIF2AK3-mediated unfolded protein response|regulation of endoplasmic reticulum unfolded protein response; PERK signaling|regulation of PERK branch of UPR|regulation of PKR-like ER kinase signal transduction http://purl.obolibrary.org/obo/GO_1903897 GO:1903896 biolink:BiologicalProcess positive regulation of IRE1-mediated unfolded protein response Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response. go-plus.json up-regulation of IRE1p unfolded protein response|upregulation of IRE1-mediated unfolded protein response|upregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|upregulation of IRE1 signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by IRE1 stress sensor|activation of UPR signaling by IRE1 stress sensor|up regulation of IRE1alpha unfolded protein response|positive regulation of IRE1 branch of UPR|positive regulation of UPR signaling by IRE1 stress sensor|upregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|positive regulation of IRE1alpha unfolded protein response|up regulation of IRE1 branch of UPR|upregulation of IRE1p unfolded protein response|up-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up-regulation of IRE1 signaling in response to endoplasmic reticulum stress|activation of IRE1alpha unfolded protein response|up regulation of IRE1-mediated unfolded protein response|activation of IRE1-mediated unfolded protein response|up-regulation of UPR signaling by IRE1 stress sensor|up regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of IRE1 signaling in response to endoplasmic reticulum stress|upregulation of IRE1 branch of UPR|activation of inositol-requiring transmembrane kinase/endonuclease signal transduction|activation of endoplasmic reticulum unfolded protein response; IRE1 signaling|positive regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|up-regulation of IRE1alpha unfolded protein response|up regulation of IRE1p unfolded protein response|positive regulation of IRE1p unfolded protein response|positive regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|positive regulation of IRE1 signaling in response to endoplasmic reticulum stress|up regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up regulation of IRE1 signaling in response to endoplasmic reticulum stress|up-regulation of IRE1-mediated unfolded protein response|upregulation of UPR signaling by IRE1 stress sensor|positive regulation of ERN1-mediated unfolded protein response|up-regulation of IRE1 branch of UPR|activation of IRE1p unfolded protein response|upregulation of IRE1alpha unfolded protein response|activation of IRE1 branch of UPR|up-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling http://purl.obolibrary.org/obo/GO_1903896 GO:1903895 biolink:BiologicalProcess negative regulation of IRE1-mediated unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response. go-plus.json down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down regulation of IRE1 signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by IRE1 stress sensor|negative regulation of IRE1 branch of UPR|downregulation of IRE1alpha unfolded protein response|down-regulation of IRE1 branch of UPR|inhibition of IRE1p unfolded protein response|down regulation of IRE1-mediated unfolded protein response|inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction|inhibition of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of UPR signaling by IRE1 stress sensor|down-regulation of UPR signaling by IRE1 stress sensor|downregulation of IRE1-mediated unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|negative regulation of IRE1alpha unfolded protein response|downregulation of IRE1 branch of UPR|down-regulation of IRE1alpha unfolded protein response|down regulation of IRE1p unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|down regulation of IRE1 branch of UPR|inhibition of IRE1 branch of UPR|inhibition of UPR signaling by IRE1 stress sensor|downregulation of IRE1p unfolded protein response|negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1-mediated unfolded protein response|down-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of IRE1alpha unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of IRE1-mediated unfolded protein response|negative regulation of IRE1p unfolded protein response|down-regulation of IRE1p unfolded protein response|downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|downregulation of IRE1 signaling in response to endoplasmic reticulum stress|down regulation of UPR signaling by IRE1 stress sensor|inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling|down regulation of IRE1alpha unfolded protein response|negative regulation of ERN1-mediated unfolded protein response http://purl.obolibrary.org/obo/GO_1903895 GO:1903894 biolink:BiologicalProcess regulation of IRE1-mediated unfolded protein response Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response. go-plus.json regulation of IRE1alpha unfolded protein response|regulation of IRE1 signal transduction pathway|regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|regulation of IRE1 branch of UPR|regulation of IRE1p unfolded protein response|regulation of ERN1-mediated unfolded protein response|regulation of IRE1 signaling in response to endoplasmic reticulum stress|regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|regulation of UPR signaling by IRE1 stress sensor http://purl.obolibrary.org/obo/GO_1903894 GO:0009089 biolink:BiologicalProcess lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate. go-plus.json lysine anabolism via diaminopimelate|lysine synthesis via diaminopimelate|diaminopimelic acid pathway|lysine formation via diaminopimelate|lysine biosynthesis via diaminopimelic acid|lysine biosynthetic process via diaminopimelic acid|diaminopimelate pathway http://purl.obolibrary.org/obo/GO_0009089 GO:0009088 biolink:BiologicalProcess threonine biosynthetic process The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. MetaCyc:HOMOSER-THRESYN-PWY|MetaCyc:THRESYN-PWY go-plus.json threonine anabolism|threonine biosynthesis|threonine synthesis|threonine formation http://purl.obolibrary.org/obo/GO_0009088 GO:1903893 biolink:BiologicalProcess positive regulation of ATF6-mediated unfolded protein response Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response. go-plus.json up-regulation of UPR signaling by ATF6 stress sensor|up regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|activation of ATF6-alpha UPR branch|upregulation of ATF6 branch of UPR|activation of endoplasmic reticulum unfolded protein response; ATF6 signaling|activation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of ATF6-beta UPR branch|positive regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of activating transcription factor 6 signaling in unfolded protein response|up-regulation of ATF6-mediated unfolded protein response|positive regulation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of ATF6-alpha UPR branch|activation of ATF6-beta UPR branch|up regulation of ATF6 signaling in response to endoplasmic reticulum stress|upregulation of UPR signaling by ATF6 stress sensor|activation of ATF6 branch of UPR|up-regulation of ATF6 branch of UPR|activation of activating transcription factor 6 signaling in unfolded protein response|up-regulation of activating transcription factor 6 signaling in unfolded protein response|positive regulation of ATF6-beta UPR branch|up-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of ATF6-mediated unfolded protein response|upregulation of ATF6-alpha UPR branch|up regulation of ATF6-beta UPR branch|upregulation of ATF6 signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by ATF6 stress sensor|activation of UPR signaling by ATF6 stress sensor|positive regulation of ATF6 branch of UPR|positive regulation of UPR signaling by ATF6 stress sensor|upregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|up regulation of ATF6 branch of UPR|positive regulation of activating transcription factor 6 signaling in unfolded protein response|up regulation of ATF6-mediated unfolded protein response|upregulation of ATF6-beta UPR branch|activation of ATF6-mediated unfolded protein response|up regulation of ATF6-alpha UPR branch|up regulation of activating transcription factor 6 signaling in unfolded protein response|up-regulation of ATF6 signaling in response to endoplasmic reticulum stress|positive regulation of ATF6-alpha UPR branch http://purl.obolibrary.org/obo/GO_1903893 GO:0034021 biolink:BiologicalProcess response to silicon dioxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus. go-plus.json response to silox|response to silica http://purl.obolibrary.org/obo/GO_0034021 GO:0009098 biolink:BiologicalProcess leucine biosynthetic process The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid. MetaCyc:LEUSYN-PWY go-plus.json leucine biosynthesis|leucine anabolism|leucine synthesis|leucine formation http://purl.obolibrary.org/obo/GO_0009098 GO:0010076 biolink:BiologicalProcess maintenance of floral meristem identity The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010076 GO:0034020 biolink:MolecularActivity neoxanthin synthase activity Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin. EC:5.3.99.9|KEGG_REACTION:R06948|RHEA:10128|MetaCyc:RXN1F-155 go-plus.json violaxanthin-neoxanthin isomerase (epoxide-opening) activity|NSY http://purl.obolibrary.org/obo/GO_0034020 GO:0009097 biolink:BiologicalProcess isoleucine biosynthetic process The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. MetaCyc:ILEUSYN-PWY go-plus.json isoleucine biosynthesis|isoleucine anabolism|isoleucine synthesis|isoleucine formation http://purl.obolibrary.org/obo/GO_0009097 GO:0010075 biolink:BiologicalProcess regulation of meristem growth Any process involved in maintaining the size and shape of a meristem. go-plus.json regulation of meristem size http://purl.obolibrary.org/obo/GO_0010075 GO:0010078 biolink:BiologicalProcess maintenance of root meristem identity The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010078 GO:0009096 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009096 GO:0009095 biolink:BiologicalProcess aromatic amino acid family biosynthetic process, prephenate pathway The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate. go-plus.json aromatic amino acid family formation, prephenate pathway|aromatic amino acid family biosynthetic process via prephenate(2-)|aromatic amino acid family biosynthetic process via prephenate|aromatic amino acid family anabolism, prephenate pathway|aromatic amino acid family synthesis, prephenate pathway http://purl.obolibrary.org/obo/GO_0009095 GO:0010077 biolink:BiologicalProcess maintenance of inflorescence meristem identity The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010077 GO:0009094 biolink:BiologicalProcess L-phenylalanine biosynthetic process The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid. go-plus.json L-phenylalanine biosynthesis|phenylalanine biosynthetic process, shikimate pathway|phenylalanine biosynthesis|phenylalanine biosynthetic process|L-phenylalanine anabolism|L-phenylalanine synthesis|L-phenylalanine formation|phenylalanine biosynthetic process, prephenate pathway http://purl.obolibrary.org/obo/GO_0009094 GO:0009093 biolink:BiologicalProcess cysteine catabolic process The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid. Wikipedia:Cysteine go-plus.json cysteine catabolism|cysteine degradation|cysteine breakdown http://purl.obolibrary.org/obo/GO_0009093 GO:0097629 biolink:CellularComponent extrinsic component of omegasome membrane The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json omegasome peripheral membrane|extrinsic to omegasome membrane http://purl.obolibrary.org/obo/GO_0097629 GO:0010079 biolink:BiologicalProcess maintenance of vegetative meristem identity The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. go-plus.json http://purl.obolibrary.org/obo/GO_0010079 GO:0009092 biolink:BiologicalProcess homoserine metabolic process The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine. go-plus.json homoserine metabolism http://purl.obolibrary.org/obo/GO_0009092 GO:0009091 biolink:BiologicalProcess homoserine catabolic process The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid. MetaCyc:HOMOCYSDEGR-PWY go-plus.json homoserine degradation|homoserine breakdown|homoserine catabolism http://purl.obolibrary.org/obo/GO_0009091 GO:0009090 biolink:BiologicalProcess homoserine biosynthetic process The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid. MetaCyc:HOMOSERSYN-PWY go-plus.json homoserine synthesis|homoserine formation|homoserine biosynthesis|homoserine anabolism http://purl.obolibrary.org/obo/GO_0009090 GO:0097626 biolink:MolecularActivity low-affinity L-arginine transmembrane transporter activity Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity L-arginine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0097626 GO:0034029 biolink:MolecularActivity 2-oxoglutarate carboxylase activity Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate. MetaCyc:RXN-8457|RHEA:20425|EC:6.4.1.7|KEGG_REACTION:R08201 go-plus.json oxalosuccinate synthetase activity|OGC|carboxylating factor for ICDH|CFI http://purl.obolibrary.org/obo/GO_0034029 GO:0097625 biolink:MolecularActivity low-affinity basic amino acid transmembrane transporter activity Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low affinity basic amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0097625 GO:0034028 biolink:MolecularActivity 5-(carboxyamino)imidazole ribonucleotide synthase activity Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate. EC:6.3.4.18|KEGG_REACTION:R07404|RHEA:19317|MetaCyc:RXN0-742 go-plus.json PurK|5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity|N5-CAIR synthetase activity|N5-carboxyaminoimidazole ribonucleotide synthetase activity http://purl.obolibrary.org/obo/GO_0034028 GO:0010070 biolink:BiologicalProcess zygote asymmetric cell division The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. go-plus.json zygote asymmetric cytokinesis http://purl.obolibrary.org/obo/GO_0010070 GO:0097628 biolink:BiologicalProcess distal tip cell migration The orderly movement of a distal tip cell. go-plus.json http://purl.obolibrary.org/obo/GO_0097628 GO:0034027 biolink:MolecularActivity (carboxyethyl)arginine beta-lactam-synthase activity Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+). MetaCyc:6.3.3.4-RXN|RHEA:23620|KEGG_REACTION:R05467|EC:6.3.3.4 go-plus.json beta-lactam synthetase activity|L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity|L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity http://purl.obolibrary.org/obo/GO_0034027 GO:0097627 biolink:MolecularActivity high-affinity L-ornithine transmembrane transporter activity Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity L-ornithine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0097627 GO:0034026 biolink:MolecularActivity L-amino-acid alpha-ligase activity Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid. EC:6.3.2.49|RHEA:44332|MetaCyc:6.3.2.28-RXN go-plus.json YwfE|L-amino acid alpha-ligase activity|bacilysin synthetase activity|L-amino acid ligase activity http://purl.obolibrary.org/obo/GO_0034026 GO:0034025 biolink:MolecularActivity D-aspartate ligase activity Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate. MetaCyc:6.3.1.12-RXN|RHEA:10752|EC:6.3.1.12 go-plus.json aslfm|D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity|D-aspartic acid-activating enzyme|UDP-MurNAc-pentapeptide:D-aspartate ligase activity http://purl.obolibrary.org/obo/GO_0034025 GO:0097622 biolink:BiologicalProcess cytoplasmic translational elongation through polyproline stretches The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0097622 GO:0010072 biolink:BiologicalProcess primary shoot apical meristem specification The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers. go-plus.json embryo shoot apical meristem specification http://purl.obolibrary.org/obo/GO_0010072 GO:0034024 biolink:MolecularActivity glutamate-putrescine ligase activity Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate. MetaCyc:RXN0-3901|RHEA:13633|EC:6.3.1.11|KEGG_REACTION:R07414 go-plus.json gamma-glutamylputrescine synthetase activity|L-glutamate:putrescine ligase (ADP-forming) activity|YcjK http://purl.obolibrary.org/obo/GO_0034024 GO:0097621 biolink:MolecularActivity monoamine oxidase activity Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2. RHEA:26414 go-plus.json amine:oxygen oxidoreductase (deaminating) activity http://purl.obolibrary.org/obo/GO_0097621 GO:0010071 biolink:BiologicalProcess root meristem specification The specification of a meristem which will give rise to a primary or lateral root. go-plus.json http://purl.obolibrary.org/obo/GO_0010071 NCBITaxon:1699513 biolink:OrganismalEntity Myrtoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1699513 GO:0034023 biolink:MolecularActivity 5-(carboxyamino)imidazole ribonucleotide mutase activity Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. MetaCyc:5.4.99.18-RXN|EC:5.4.99.18|RHEA:13193 go-plus.json PurE|class I PurE|N5-CAIR mutase activity|N5-carboxyaminoimidazole ribonucleotide mutase activity|5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity http://purl.obolibrary.org/obo/GO_0034023 GO:0010074 biolink:BiologicalProcess maintenance of meristem identity The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. go-plus.json meristem cell maintenance|maintenance of meristem cell identity http://purl.obolibrary.org/obo/GO_0010074 GO:0097624 biolink:BiologicalProcess UDP-galactose transmembrane import into Golgi lumen The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane. go-plus.json UDP-galactose import into Golgi lumen http://purl.obolibrary.org/obo/GO_0097624 GO:0097623 biolink:BiologicalProcess potassium ion export across plasma membrane The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json potassium export|potassium export across plasma membrane|potassium ion export from cell|potassium ion export http://purl.obolibrary.org/obo/GO_0097623 GO:0034022 biolink:MolecularActivity 3-(hydroxyamino)phenol mutase activity Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone. UM-BBD_enzymeID:e0953|MetaCyc:5.4.4.3-RXN|RHEA:20577|KEGG_REACTION:R06988|EC:5.4.4.3 go-plus.json 3-hydroxylaminophenol mutase activity|3HAP mutase activity|3-(hydroxyamino)phenol hydroxymutase activity http://purl.obolibrary.org/obo/GO_0034022 GO:0010073 biolink:BiologicalProcess meristem maintenance Any process involved in maintaining the identity, size and shape of a meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0010073 GO:0097673 biolink:CellularComponent SCF-Ucc1 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae. go-plus.json SCF-YLR224W ubiquitin ligase complex http://purl.obolibrary.org/obo/GO_0097673 GO:0097672 biolink:CellularComponent SCF-Pof5 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae). go-plus.json SCF-YDR306C ubiquitin ligase complex http://purl.obolibrary.org/obo/GO_0097672 UBERON:0035083 biolink:AnatomicalEntity transverse process-bearing vertebra A vertebra that has a transverse process. go-plus.json pygal vertebra|TP vertebra http://purl.obolibrary.org/obo/UBERON_0035083 GO:0097675 biolink:CellularComponent SCF-Hrt3/Pof7 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097675 GO:0097674 biolink:CellularComponent SCF-YLR352W ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097674 GO:0097671 biolink:CellularComponent SCF-YDR131C ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097671 GO:0034019 biolink:MolecularActivity obsolete capsanthin/capsorubin synthase activity OBSOLETE. Catalysis of the reactions: violaxanthin = capsorubin, and antheraxanthin = capsanthin. go-plus.json capsanthin-capsorubin synthase activity|CCS|violaxanthin-capsorubin isomerase (ketone-forming) activity|ketoxanthophyll synthase activity|capsanthin/capsorubin synthase activity http://purl.obolibrary.org/obo/GO_0034019 GO:0097670 biolink:CellularComponent SCF-Ufo1/Pof10 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097670 GO:0009059 biolink:BiologicalProcess macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json macromolecule synthesis|macromolecule formation|biopolymer biosynthetic process|macromolecule biosynthesis|macromolecule anabolism http://purl.obolibrary.org/obo/GO_0009059 goslim_pir GO:0009058 biolink:BiologicalProcess biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. Wikipedia:Anabolism go-plus.json formation|anabolism|multicellular organismal biosynthetic process|synthesis|single-organism biosynthetic process|biosynthesis http://purl.obolibrary.org/obo/GO_0009058 goslim_plant|goslim_metagenomics|goslim_generic|goslim_chembl GO:0009057 biolink:BiologicalProcess macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json biopolymer catabolic process|macromolecule catabolism|macromolecule degradation|macromolecule breakdown|multicellular organismal macromolecule catabolic process http://purl.obolibrary.org/obo/GO_0009057 goslim_pir GO:0009056 biolink:BiologicalProcess catabolic process The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. Wikipedia:Catabolism go-plus.json degradation|breakdown|multicellular organismal catabolic process|single-organism catabolic process|catabolism http://purl.obolibrary.org/obo/GO_0009056 goslim_plant|goslim_generic|goslim_chembl|goslim_agr GO:0009055 biolink:MolecularActivity electron transfer activity Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. Reactome:R-HSA-2564826|Reactome:R-HSA-169260 go-plus.json electron carrier|electron transporter activity|electron donor activity|electron acceptor activity http://purl.obolibrary.org/obo/GO_0009055 goslim_pir|goslim_metagenomics GO:0034010 biolink:MolecularActivity sulfolactate sulfo-lyase activity Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite. EC:4.4.1.24|KEGG_REACTION:R07633|MetaCyc:4.4.1.24-RXN|RHEA:21428 go-plus.json 3-sulfolactate bisulfite-lyase activity|3-sulfolactate bisulfite-lyase (pyruvate-forming) activity|SuyAB|Suy http://purl.obolibrary.org/obo/GO_0034010 GO:0009065 biolink:BiologicalProcess glutamine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. go-plus.json glutamine family amino acid degradation|glutamine family amino acid breakdown|glutamine family amino acid catabolism http://purl.obolibrary.org/obo/GO_0009065 GO:0010043 biolink:BiologicalProcess response to zinc ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. go-plus.json response to zinc http://purl.obolibrary.org/obo/GO_0010043 GO:0010042 biolink:BiologicalProcess response to manganese ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. go-plus.json response to manganese http://purl.obolibrary.org/obo/GO_0010042 GO:0009064 biolink:BiologicalProcess glutamine family amino acid metabolic process The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. go-plus.json glutamine family amino acid metabolism http://purl.obolibrary.org/obo/GO_0009064 GO:0010045 biolink:BiologicalProcess response to nickel cation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus. go-plus.json response to nickel http://purl.obolibrary.org/obo/GO_0010045 GO:0009063 biolink:BiologicalProcess cellular amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. go-plus.json amino acid catabolic process|cellular amino acid degradation|cellular amino acid catabolism|cellular amino acid breakdown http://purl.obolibrary.org/obo/GO_0009063 GO:0009062 biolink:BiologicalProcess fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. Wikipedia:Fatty_acid_degradation go-plus.json fatty acid catabolism|fatty acid degradation|fatty acid breakdown http://purl.obolibrary.org/obo/GO_0009062 GO:0010044 biolink:BiologicalProcess response to aluminum ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus. go-plus.json response to aluminium ion|response to aluminum http://purl.obolibrary.org/obo/GO_0010044 GO:0009061 biolink:BiologicalProcess anaerobic respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor. Wikipedia:Anaerobic_respiration|MetaCyc:ANARESP1-PWY|Wikipedia:Cellular_respiration#Anaerobic_respiration go-plus.json http://purl.obolibrary.org/obo/GO_0009061 GO:0010047 biolink:BiologicalProcess fruit dehiscence The process leading to the spontaneous opening of the fruit permitting the escape of seeds. go-plus.json http://purl.obolibrary.org/obo/GO_0010047 GO:0010046 biolink:BiologicalProcess response to mycotoxin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0010046 GO:0009060 biolink:BiologicalProcess aerobic respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. MetaCyc:PWY-3781|Wikipedia:Cellular_respiration#Aerobic_respiration go-plus.json http://purl.obolibrary.org/obo/GO_0009060 GO:0010049 biolink:BiologicalProcess acquisition of plant reproductive competence The process in which a plant acquires the ability to respond to a floral inductive signal. go-plus.json acquisition of reproductive competence http://purl.obolibrary.org/obo/GO_0010049 GO:0010048 biolink:BiologicalProcess vernalization response The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures. go-plus.json http://purl.obolibrary.org/obo/GO_0010048 GO:0034018 biolink:MolecularActivity ascopyrone tautomerase activity Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose. RHEA:22568|EC:5.3.2.7|MetaCyc:5.3.3.15-RXN go-plus.json ascopyrone P tautomerase activity|APTM|1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity|1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity|ascopyrone isomerase activity|APM tautomerase activity|ascopyrone intramolecular oxidoreductase activity http://purl.obolibrary.org/obo/GO_0034018 GO:0034017 biolink:MolecularActivity trans-2-decenoyl-acyl-carrier-protein isomerase activity Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein]. RHEA:23568|EC:5.3.3.14|MetaCyc:5.3.3.14-RXN go-plus.json trans-2, cis-3 decenoyl-ACP isomerase activity|FabM|trans-2,cis-3-decenoyl-ACP isomerase activity|trans-2-cis-3-decenoyl-ACP isomerase activity|decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity|trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity|trans-2-decenoyl-ACP isomerase activity|beta-hydroxydecanoyl thioester dehydrase activity http://purl.obolibrary.org/obo/GO_0034017 GO:0034016 biolink:MolecularActivity polyenoic fatty acid isomerase activity Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate. RHEA:14889|EC:5.3.3.13|KEGG_REACTION:R06502|MetaCyc:5.3.3.13-RXN go-plus.json PFI|eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity|(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity|(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity|(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity http://purl.obolibrary.org/obo/GO_0034016 GO:0034015 biolink:MolecularActivity L-ribulose-5-phosphate 3-epimerase activity Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate. MetaCyc:LXULRU5P-RXN|EC:5.1.3.22|RHEA:18497 go-plus.json L-xylulose 5-phosphate 3-epimerase activity|SgaU|UlaE http://purl.obolibrary.org/obo/GO_0034015 GO:0097677 biolink:MolecularActivity STAT family protein binding Binding to a member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses. go-plus.json signal transducers and activators of transcription family protein binding http://purl.obolibrary.org/obo/GO_0097677 GO:0034014 biolink:BiologicalProcess response to triglyceride Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus. go-plus.json response to triacylglyceride|response to triacylglycerol http://purl.obolibrary.org/obo/GO_0034014 GO:0034013 biolink:MolecularActivity aliphatic aldoxime dehydratase activity Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O. RHEA:11316|EC:4.99.1.5|MetaCyc:4.99.1.5-RXN go-plus.json aliphatic aldoxime hydro-lyase activity|aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity|OxdA http://purl.obolibrary.org/obo/GO_0034013 GO:0097676 biolink:BiologicalProcess histone H3-K36 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0097676 GO:0010041 biolink:BiologicalProcess response to iron(III) ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus. go-plus.json response to iron(III) http://purl.obolibrary.org/obo/GO_0010041 GO:0034012 biolink:MolecularActivity FAD-AMP lyase (cyclizing) activity Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate. EC:4.6.1.15|RHEA:13729 go-plus.json FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity|FAD AMP-lyase (cyclic-FMN-forming) activity|FMN cyclase activity http://purl.obolibrary.org/obo/GO_0034012 GO:0097679 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097679 GO:0097678 biolink:MolecularActivity SOCS family protein binding Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions. go-plus.json suppressor of cytokine signaling family protein binding http://purl.obolibrary.org/obo/GO_0097678 GO:0034011 biolink:MolecularActivity L-cysteate sulfo-lyase activity Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite. KEGG_REACTION:R07634|RHEA:13441|MetaCyc:4.4.1.25-RXN|EC:4.4.1.25 go-plus.json L-cysteate sulfo-lyase (deaminating) activity|L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity|CuyA http://purl.obolibrary.org/obo/GO_0034011 GO:0010040 biolink:BiologicalProcess response to iron(II) ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus. go-plus.json response to iron(II) http://purl.obolibrary.org/obo/GO_0010040 GO:0097684 biolink:CellularComponent dinoflagellate antapex The anterior most point of a dinoflagellate hypocone. go-plus.json antapex http://purl.obolibrary.org/obo/GO_0097684 GO:0097683 biolink:CellularComponent dinoflagellate apex The anterior most point of a dinoflagellate epicone. go-plus.json apex http://purl.obolibrary.org/obo/GO_0097683 UBERON:0035091 biolink:AnatomicalEntity extrinsic post-anal tail muscle A post-anal tail that attaches outside the tail. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035091 GO:0097686 biolink:CellularComponent dinoflagellate apical horn A horn-shaped dinoflagellate apex found in thecate species. go-plus.json http://purl.obolibrary.org/obo/GO_0097686 GO:0097685 biolink:CellularComponent dinoflagellate apical groove A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex. go-plus.json apical groove http://purl.obolibrary.org/obo/GO_0097685 GO:0097680 biolink:BiologicalProcess double-strand break repair via classical nonhomologous end joining An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining). go-plus.json canonical nonhomologous end joining|C-NHEJ http://purl.obolibrary.org/obo/GO_0097680 GO:0034009 biolink:MolecularActivity isoprene synthase activity Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene. MetaCyc:4.2.3.27-RXN|KEGG_REACTION:R08199|EC:4.2.3.27|RHEA:13369 go-plus.json dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity|ISPC|ISPS http://purl.obolibrary.org/obo/GO_0034009 GO:0097682 biolink:MolecularActivity intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0097682 GO:0034008 biolink:MolecularActivity R-linalool synthase activity Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate. MetaCyc:4.2.3.26-RXN|RHEA:15809|EC:4.2.3.26|KEGG_REACTION:R07632 go-plus.json (3R)-linalool synthase activity|geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity|(-)-3R-linalool synthase activity http://purl.obolibrary.org/obo/GO_0034008 GO:0097681 biolink:BiologicalProcess double-strand break repair via alternative nonhomologous end joining An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment. go-plus.json A-NHEJ|MMEJ|alt-NHEJ|double-strand break repair via microhomology-mediated end joining http://purl.obolibrary.org/obo/GO_0097681 GO:0009069 biolink:BiologicalProcess serine family amino acid metabolic process The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. go-plus.json serine family amino acid metabolism http://purl.obolibrary.org/obo/GO_0009069 GO:0009068 biolink:BiologicalProcess aspartate family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. go-plus.json aspartate family amino acid degradation|aspartate family amino acid breakdown|aspartate family amino acid catabolism http://purl.obolibrary.org/obo/GO_0009068 GO:0009067 biolink:BiologicalProcess aspartate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. go-plus.json aspartate family amino acid biosynthesis|aspartate family amino acid anabolism|aspartate family amino acid synthesis|aspartate family amino acid formation http://purl.obolibrary.org/obo/GO_0009067 GO:0009066 biolink:BiologicalProcess aspartate family amino acid metabolic process The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. go-plus.json aspartate family amino acid metabolism http://purl.obolibrary.org/obo/GO_0009066 GO:0009076 biolink:BiologicalProcess obsolete histidine family amino acid biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family. go-plus.json histidine family amino acid anabolism|histidine family amino acid synthesis|histidine family amino acid formation|histidine family amino acid biosynthetic process|histidine family amino acid biosynthesis http://purl.obolibrary.org/obo/GO_0009076 GO:0010054 biolink:BiologicalProcess trichoblast differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair. go-plus.json trichoblast cell differentiation http://purl.obolibrary.org/obo/GO_0010054 GO:0009075 biolink:BiologicalProcess obsolete histidine family amino acid metabolic process OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family. go-plus.json histidine family amino acid metabolic process|histidine family amino acid metabolism http://purl.obolibrary.org/obo/GO_0009075 GO:0010053 biolink:BiologicalProcess root epidermal cell differentiation The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast. go-plus.json http://purl.obolibrary.org/obo/GO_0010053 GO:0009074 biolink:BiologicalProcess aromatic amino acid family catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). go-plus.json aromatic amino acid family breakdown|aromatic amino acid family catabolism|aromatic amino acid family degradation http://purl.obolibrary.org/obo/GO_0009074 GO:0010056 biolink:BiologicalProcess atrichoblast fate specification The process involved in the specification of an atrichoblast. go-plus.json http://purl.obolibrary.org/obo/GO_0010056 GO:0010055 biolink:BiologicalProcess atrichoblast differentiation The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair. go-plus.json http://purl.obolibrary.org/obo/GO_0010055 GO:0009073 biolink:BiologicalProcess aromatic amino acid family biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). MetaCyc:COMPLETE-ARO-PWY go-plus.json aromatic amino acid family biosynthetic process, shikimate pathway|aromatic amino acid family anabolism|aromatic amino acid family synthesis|aromatic amino acid family formation|aromatic amino acid family biosynthesis http://purl.obolibrary.org/obo/GO_0009073 GO:0009072 biolink:BiologicalProcess aromatic amino acid family metabolic process The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). go-plus.json aromatic amino acid family metabolism http://purl.obolibrary.org/obo/GO_0009072 GO:0010058 biolink:BiologicalProcess regulation of atrichoblast fate specification Any process that modulates atrichoblast fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0010058 SO:0000628 biolink:SequenceFeature chromosomal_structural_element Regions of the chromosome that are important for structural elements. go-plus.json chromosomal structural element http://purl.obolibrary.org/obo/SO_0000628 SOFA GO:0009071 biolink:BiologicalProcess serine family amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. go-plus.json serine family amino acid degradation|serine family amino acid breakdown|serine family amino acid catabolism http://purl.obolibrary.org/obo/GO_0009071 GO:0010057 biolink:BiologicalProcess trichoblast fate specification The process involved in the specification of a trichoblast. go-plus.json http://purl.obolibrary.org/obo/GO_0010057 SO:0000627 biolink:SequenceFeature insulator A regulatory region that 1) when located between a CRM and a gene's promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region. http://en.wikipedia.org/wiki/Insulator_(genetics) go-plus.json INSDC_feature:regulatory|INSDC_qualifier:insulator|insulator element http://purl.obolibrary.org/obo/SO_0000627 SOFA GO:0009070 biolink:BiologicalProcess serine family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. go-plus.json serine family amino acid anabolism|serine family amino acid biosynthesis|serine family amino acid synthesis|serine family amino acid formation http://purl.obolibrary.org/obo/GO_0009070 GO:0010059 biolink:BiologicalProcess positive regulation of atrichoblast fate specification Any process that induces or promotes atrichoblast fate specification. go-plus.json up-regulation of atrichoblast fate|upregulation of atrichoblast fate|up regulation of atrichoblast fate|activation of atrichoblast fate|stimulation of atrichoblast fate http://purl.obolibrary.org/obo/GO_0010059 GO:0034007 biolink:MolecularActivity S-linalool synthase activity Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate. MetaCyc:4.2.3.25-RXN|EC:4.2.3.25|RHEA:24116|KEGG_REACTION:R07631 go-plus.json LIS|3S-linalool synthase activity|geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity http://purl.obolibrary.org/obo/GO_0034007 SO:0000624 biolink:SequenceFeature telomere A specific structure at the end of a linear chromosome, required for the integrity and maintenance of the end. http://en.wikipedia.org/wiki/Telomere go-plus.json telomeric sequence|telomeric DNA|INSDC_feature:telomere http://purl.obolibrary.org/obo/SO_0000624 SOFA GO:0034006 biolink:MolecularActivity amorpha-4,11-diene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate. MetaCyc:4.2.3.24-RXN|MetaCyc:RXN-8046|EC:4.2.3.24|RHEA:18325|KEGG_REACTION:R07630 go-plus.json 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity|amorphadiene synthase activity http://purl.obolibrary.org/obo/GO_0034006 GO:0034005 biolink:MolecularActivity germacrene-A synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate. MetaCyc:4.2.3.23-RXN|RHEA:12516|KEGG_REACTION:R07649|EC:4.2.3.23 go-plus.json (+)-germacrene A synthase activity|germacrene A synthase activity|GAS|(+)-(10R)-germacrene A synthase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity http://purl.obolibrary.org/obo/GO_0034005 SO:0000625 biolink:SequenceFeature silencer A regulatory region which upon binding of transcription factors, suppress the transcription of the gene or genes they control. http://en.wikipedia.org/wiki/Silencer_(DNA) go-plus.json INSDC_feature:regulatory|INSDC_qualifier:silencer http://purl.obolibrary.org/obo/SO_0000625 SOFA GO:0034004 biolink:MolecularActivity germacradienol synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate. MetaCyc:RXN-8648|RHEA:22436|EC:4.2.3.22|KEGG_REACTION:R07647 go-plus.json 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity http://purl.obolibrary.org/obo/GO_0034004 GO:0097688 biolink:BiologicalProcess glutamate receptor clustering The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane. go-plus.json glutamatergic receptor clustering http://purl.obolibrary.org/obo/GO_0097688 GO:0034003 biolink:MolecularActivity vetispiradiene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene. MetaCyc:RXN-4823|EC:4.2.3.21|KEGG_REACTION:R06523|RHEA:10340 go-plus.json vetispiradiene-forming farnesyl pyrophosphate cyclase activity|vetispiradiene cyclase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity|pemnaspirodiene synthase activity|HVS http://purl.obolibrary.org/obo/GO_0034003 GO:0010050 biolink:BiologicalProcess vegetative phase change Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development. go-plus.json http://purl.obolibrary.org/obo/GO_0010050 GO:0097687 biolink:CellularComponent dinoflagellate antapical horn A horn-shaped dinoflagellate antapex found in thecate species. go-plus.json http://purl.obolibrary.org/obo/GO_0097687 GO:0034002 biolink:MolecularActivity (R)-limonene synthase activity Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate. MetaCyc:4.2.3.20-RXN|RHEA:10940|EC:4.2.3.20|KEGG_REACTION:R06120 go-plus.json geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity|(+)-limonene synthase activity|geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity http://purl.obolibrary.org/obo/GO_0034002 GO:0034001 biolink:MolecularActivity chondroitin-sulfate-ABC exolyase activity Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments. MetaCyc:4.2.2.21-RXN|EC:4.2.2.21 go-plus.json chondroitinase activity|chondroitinase ABC activity|chondroitin sulfate ABC lyase activity|chondroitin ABC eliminase activity|ChS ABC lyase activity|chondroitin sulfate ABC exoeliminase activity|chondroitin sulfate ABC exolyase activity|ChS ABC lyase II activity http://purl.obolibrary.org/obo/GO_0034001 GO:0010052 biolink:BiologicalProcess guard cell differentiation The process in which a guard mother cell acquires the specialized features of a guard cell. go-plus.json stomatal cell differentiation http://purl.obolibrary.org/obo/GO_0010052 GO:0034000 biolink:MolecularActivity chondroitin-sulfate-ABC endolyase activity Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides. MetaCyc:4.2.2.20-RXN|EC:4.2.2.20 go-plus.json chondroitinase ABC activity|chondroitin sulfate ABC lyase activity|chondroitin sulfate ABC endoeliminase activity|chondroitin sulfate ABC endolyase activity|chondroitin ABC eliminase activity|ChS ABC lyase activity|ChS ABC lyase I activity|chondroitinase activity http://purl.obolibrary.org/obo/GO_0034000 GO:0097689 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0097689 GO:0010051 biolink:BiologicalProcess xylem and phloem pattern formation The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana. go-plus.json vascular tissue pattern formation http://purl.obolibrary.org/obo/GO_0010051 GO:0097651 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class I A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast. go-plus.json class I PI3K complex|class I phosphatidylinositol 3-kinase complex http://purl.obolibrary.org/obo/GO_0097651 GO:0097650 biolink:CellularComponent B axonemal microtubule An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet. go-plus.json B tubule http://purl.obolibrary.org/obo/GO_0097650 GO:0097653 biolink:CellularComponent unencapsulated part of cell The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures. go-plus.json non-encapsulated part of cell http://purl.obolibrary.org/obo/GO_0097653 GO:0097652 biolink:CellularComponent phosphatidylinositol 3-kinase complex, class II A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast. go-plus.json class II PI3K complex|class II phosphatidylinositol 3-kinase complex http://purl.obolibrary.org/obo/GO_0097652 GO:0010029 biolink:BiologicalProcess regulation of seed germination Any process that modulates the frequency, rate or extent of seed germination. go-plus.json http://purl.obolibrary.org/obo/GO_0010029 GO:0009039 biolink:MolecularActivity urease activity Catalysis of the reaction: urea + H2O = CO2 + 2 NH3. UM-BBD_reactionID:r0120|EC:3.5.1.5|MetaCyc:UREASE-RXN|RHEA:20557 go-plus.json urea amidohydrolase activity http://purl.obolibrary.org/obo/GO_0009039 GO:0010028 biolink:BiologicalProcess xanthophyll cycle A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II. Wikipedia:Xanthophyll#Xanthophyll_cycle|MetaCyc:PWY-1141 go-plus.json http://purl.obolibrary.org/obo/GO_0010028 CHEBI:133999 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133999 GO:0009038 biolink:MolecularActivity undecaprenol kinase activity Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate. EC:2.7.1.66 go-plus.json C55-isoprenyl alcohol phosphokinase activity|polyisoprenol kinase activity|isoprenoid alcohol phosphokinase activity|isoprenoid alcohol kinase (phosphorylating)|isoprenoid-alcohol kinase activity|ATP:undecaprenol phosphotransferase activity|C55-isoprenoid alcohol phosphokinase activity|C55-isoprenoid alcohol kinase activity|isoprenoid alcohol kinase activity http://purl.obolibrary.org/obo/GO_0009038 GO:0009037 biolink:MolecularActivity tyrosine-based site-specific recombinase activity Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site. go-plus.json site-specific tyrosine recombinase activity|tyrosine recombinase http://purl.obolibrary.org/obo/GO_0009037 GO:0009036 biolink:MolecularActivity type II site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site. EC:3.1.21.4|MetaCyc:3.1.21.4-RXN go-plus.json type II restriction enzyme activity http://purl.obolibrary.org/obo/GO_0009036 GO:0009035 biolink:MolecularActivity type I site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA. MetaCyc:3.1.21.3-RXN|EC:3.1.21.3 go-plus.json deoxyribonuclease (adenosine triphosphate-hydrolyzing)|type I restriction enzyme activity|adenosine triphosphate-dependent deoxyribonuclease activity|type I site-specific deoxyribonuclease activity|deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)|ATP-dependent DNase activity http://purl.obolibrary.org/obo/GO_0009035 GO:0009034 biolink:MolecularActivity tryptophanase activity Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate. MetaCyc:TRYPDEG-PWY|RHEA:19553|MetaCyc:TRYPTOPHAN-RXN|EC:4.1.99.1|UniPathway:UPA00332|KEGG_REACTION:R00673 go-plus.json L-tryptophanase activity|L-tryptophan indole-lyase (deaminating) activity|L-tryptophan indole-lyase activity|tryptophan catabolic process, using tryptophanase|L-tryptophan indole-lyase (deaminating; pyruvate forming) activity|TNase activity|tryptophan catabolism, using tryptophanase http://purl.obolibrary.org/obo/GO_0009034 GO:0009033 biolink:MolecularActivity trimethylamine-N-oxide reductase activity Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O. RHEA:22024|MetaCyc:TMAOREDUCT-RXN go-plus.json trimethylamine oxide reductase|trimethylamine oxidase activity|NADH:trimethylamine-N-oxide oxidoreductase|trimethylamine N-oxide reductase http://purl.obolibrary.org/obo/GO_0009033 GO:0009043 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009043 CHEBI:133992 biolink:ChemicalSubstance N-oleoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133992 chebi_ph7_3 GO:0010021 biolink:BiologicalProcess amylopectin biosynthetic process The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages. go-plus.json amylopectin anabolism|amylopectin biosynthesis|amylopectin synthesis|amylopectin formation http://purl.obolibrary.org/obo/GO_0010021 GO:0009042 biolink:MolecularActivity valine-pyruvate transaminase activity Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. RHEA:22912|KEGG_REACTION:R01215|EC:2.6.1.66|MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN go-plus.json alanine-oxoisovalerate aminotransferase activity|valine--pyruvate aminotransferase activity|L-valine:pyruvate aminotransferase activity|transaminase C activity|alanine--valine transaminase activity|valine-pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0009042 CHEBI:133991 biolink:ChemicalSubstance (9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133991 chebi_ph7_3 GO:0010020 biolink:BiologicalProcess chloroplast fission The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis. go-plus.json chloroplast division http://purl.obolibrary.org/obo/GO_0010020 GO:0010023 biolink:BiologicalProcess proanthocyanidin biosynthetic process The chemical reactions and pathways resulting in the formation of proanthocyanidin. MetaCyc:PWY-641 go-plus.json proanthocyanidin anabolism|proanthocyanidin synthesis|proanthocyanidin formation|proanthocyanidin biosynthesis http://purl.obolibrary.org/obo/GO_0010023 GO:0009041 biolink:MolecularActivity uridylate kinase activity Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP. EC:2.7.4.22 go-plus.json http://purl.obolibrary.org/obo/GO_0009041 CHEBI:133994 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133994 GO:0010022 biolink:BiologicalProcess meristem determinacy The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate). go-plus.json http://purl.obolibrary.org/obo/GO_0010022 GO:0009040 biolink:MolecularActivity ureidoglycolate dehydrogenase activity Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+. MetaCyc:R165-RXN|EC:1.1.1.154 go-plus.json (S)-ureidoglycolate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0009040 CHEBI:133993 biolink:ChemicalSubstance 4'-O-methylnorbelladine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133993 chebi_ph7_3 GO:0010025 biolink:BiologicalProcess wax biosynthetic process The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids. MetaCyc:PWY-282 go-plus.json wax synthesis|wax formation|wax biosynthesis|wax anabolism http://purl.obolibrary.org/obo/GO_0010025 CHEBI:133996 biolink:ChemicalSubstance (4aR,10bS)-noroxomaritidine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133996 chebi_ph7_3 GO:0010024 biolink:BiologicalProcess phytochromobilin biosynthetic process The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha. go-plus.json phytochromobilin biosynthesis|phytochromobilin anabolism|phytochromobilin synthesis|phytochromobilin formation http://purl.obolibrary.org/obo/GO_0010024 CHEBI:133995 biolink:ChemicalSubstance (4aS,10bR)-noroxomaritidine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133995 chebi_ph7_3 GO:0010027 biolink:BiologicalProcess thylakoid membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane. go-plus.json thylakoid membrane organisation|thylakoid membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0010027 CHEBI:133998 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133998 GO:0010026 biolink:BiologicalProcess trichome differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana. go-plus.json trichome cell differentiation http://purl.obolibrary.org/obo/GO_0010026 GO:0097659 biolink:BiologicalProcess nucleic acid-templated transcription The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA). go-plus.json http://purl.obolibrary.org/obo/GO_0097659 goslim_mouse|gocheck_do_not_manually_annotate SO:0000657 biolink:SequenceFeature repeat_region A region of sequence containing one or more repeat units. go-plus.json INSDC_qualifier:other|repeat region|INSDC_feature:repeat_region http://purl.obolibrary.org/obo/SO_0000657 SOFA GO:0097658 biolink:CellularComponent Asi complex A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p. go-plus.json http://purl.obolibrary.org/obo/GO_0097658 CHEBI:456215 biolink:ChemicalSubstance adenosine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_456215 chebi_ph7_3 GO:0097655 biolink:MolecularActivity serpin family protein binding Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors. go-plus.json SERPIN family protein binding http://purl.obolibrary.org/obo/GO_0097655 GO:0097654 biolink:CellularComponent platelet SNARE complex A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4. go-plus.json http://purl.obolibrary.org/obo/GO_0097654 GO:0097657 biolink:MolecularActivity 3',5'-nucleotide bisphosphate phosphatase activity Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate. EC:3.1.3.97|RHEA:43532 go-plus.json http://purl.obolibrary.org/obo/GO_0097657 SO:0000655 biolink:SequenceFeature ncRNA An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product. http://www.gencodegenes.org/gencode_biotypes.html|http://en.wikipedia.org/wiki/NcRNA go-plus.json INSDC_qualifier:other|noncoding RNA|known_ncrna http://purl.obolibrary.org/obo/SO_0000655 SOFA CHEBI:133990 biolink:ChemicalSubstance (9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133990 CHEBI:456216 biolink:ChemicalSubstance ADP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_456216 chebi_ph7_3 GO:0097656 biolink:BiologicalProcess cell-cell self recognition A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development. go-plus.json kin recognition|kin discrimination|self recognition http://purl.obolibrary.org/obo/GO_0097656 GO:0097662 biolink:CellularComponent SCF-Das1 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097662 GO:0097661 biolink:CellularComponent SCF-Ctf13 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097661 GO:0097664 biolink:CellularComponent SCF-Grr1/Pof2 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097664 SO:0000651 biolink:SequenceFeature cytosolic_LSU_rRNA Cytosolic LSU rRNA is an RNA component of the large subunit of cytosolic ribosomes. go-plus.json cytosolic LSU rRNA|cytosolic LSU RNA|cytosolic large subunit rRNA http://purl.obolibrary.org/obo/SO_0000651 SOFA GO:0097663 biolink:CellularComponent SCF-Dia2/Pof3 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097663 GO:0097660 biolink:CellularComponent SCF-Cdc4 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097660 GO:0010039 biolink:BiologicalProcess response to iron ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. go-plus.json response to iron http://purl.obolibrary.org/obo/GO_0010039 GO:0009049 biolink:MolecularActivity obsolete aspartic-type signal peptidase activity OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism. go-plus.json aspartic-type signal peptidase activity http://purl.obolibrary.org/obo/GO_0009049 GO:0009048 biolink:BiologicalProcess dosage compensation by inactivation of X chromosome Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex. Wikipedia:X-inactivation go-plus.json chromosome inactivation|Barr body formation|X chromosome inactivation http://purl.obolibrary.org/obo/GO_0009048 GO:0009047 biolink:BiologicalProcess dosage compensation by hyperactivation of X chromosome Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0009047 GO:0009046 biolink:MolecularActivity zinc D-Ala-D-Ala carboxypeptidase activity Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine. MetaCyc:3.4.17.14-RXN|EC:3.4.17.14 go-plus.json DD-carboxypeptidase|Zn2+ G peptidase activity|G enzyme|DD-carboxypeptidase-transpeptidase activity|D-alanyl-D-alanine hydrolase activity|Zn(2+) G peptidase activity|D-alanyl-D-alanine-cleaving carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0009046 GO:0009045 biolink:MolecularActivity xylose isomerase activity Catalysis of the reaction: D-xylose = D-xylulose. RHEA:22816|EC:5.3.1.5|MetaCyc:XYLISOM-RXN go-plus.json D-xylose aldose-ketose-isomerase activity|D-xylose isomerase activity|D-xylose ketol-isomerase activity|D-xylose ketoisomerase activity http://purl.obolibrary.org/obo/GO_0009045 GO:0009044 biolink:MolecularActivity xylan 1,4-beta-xylosidase activity Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini. EC:3.2.1.37|MetaCyc:3.2.1.37-RXN go-plus.json 1,4-beta-D-xylan xylohydrolase activity|exo-1,4-beta-xylosidase activity|beta-xylosidase activity|beta-D-xylopyranosidase activity|xylobiase activity|exo-1,4-beta-D-xylosidase activity|exo-1,4-xylosidase activity http://purl.obolibrary.org/obo/GO_0009044 GO:0009054 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009054 GO:0010032 biolink:BiologicalProcess meiotic chromosome condensation Compaction of chromatin structure prior to meiosis in eukaryotic cells. go-plus.json chromosome condensation involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0010032 GO:0009053 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0009053 GO:0010031 biolink:BiologicalProcess circumnutation The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth. go-plus.json http://purl.obolibrary.org/obo/GO_0010031 GO:0009052 biolink:BiologicalProcess pentose-phosphate shunt, non-oxidative branch The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P. MetaCyc:P21-PWY|MetaCyc:NONOXIPENT-PWY go-plus.json pentose phosphate pathway, non-oxidative branch|pentose phosphate shunt, non-oxidative branch|pentose-phosphate pathway, non-oxidative branch http://purl.obolibrary.org/obo/GO_0009052 GO:0010034 biolink:BiologicalProcess response to acetate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010034 GO:0010033 biolink:BiologicalProcess response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. go-plus.json process resulting in tolerance to organic substance http://purl.obolibrary.org/obo/GO_0010033 GO:0009051 biolink:BiologicalProcess pentose-phosphate shunt, oxidative branch The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2). MetaCyc:OXIDATIVEPENT-PWY go-plus.json pentose phosphate pathway, oxidative branch|pentose phosphate shunt, oxidative branch|oxidative branch, pentose pathway|pentose-phosphate pathway, oxidative branch|oxidative pentose phosphate pathway http://purl.obolibrary.org/obo/GO_0009051 GO:0010036 biolink:BiologicalProcess response to boron-containing substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus. go-plus.json response to boron http://purl.obolibrary.org/obo/GO_0010036 GO:0009050 biolink:BiologicalProcess glycopeptide catabolic process The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide. go-plus.json glycopeptide catabolism|glycopeptide degradation|glycopeptide breakdown http://purl.obolibrary.org/obo/GO_0009050 GO:0010035 biolink:BiologicalProcess response to inorganic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010035 GO:0010038 biolink:BiologicalProcess response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. go-plus.json response to heavy metal|response to metal|heavy metal sensitivity/resistance http://purl.obolibrary.org/obo/GO_0010038 GO:0010037 biolink:BiologicalProcess response to carbon dioxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0010037 SO:0000646 biolink:SequenceFeature siRNA A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. siRNAs trigger the cleavage of their target molecules. http://en.wikipedia.org/wiki/SiRNA go-plus.json small interfering RNA|INSDC_feature:ncRNA|INSDC_qualifier:siRNA http://purl.obolibrary.org/obo/SO_0000646 SOFA GO:0097669 biolink:CellularComponent SCF-Skp2 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097669 GO:0097666 biolink:CellularComponent SCF-Met30/Pof1 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097666 GO:0097665 biolink:CellularComponent SCF-Mdm30 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0097665 SO:0000644 biolink:SequenceFeature antisense_RNA Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA. http://en.wikipedia.org/wiki/Antisense_RNA go-plus.json antisense RNA|INSDC_qualifier:antisense_RNA|INSDC_feature:ncRNA http://purl.obolibrary.org/obo/SO_0000644 SOFA GO:0010030 biolink:BiologicalProcess positive regulation of seed germination Any process that activates or increase the rate of seed germination. go-plus.json stimulation of seed germination|up-regulation of seed germination|activation of seed germination|up regulation of seed germination|upregulation of seed germination http://purl.obolibrary.org/obo/GO_0010030 GO:0097668 biolink:CellularComponent SCF-Saf1/Pof9 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097668 GO:0097667 biolink:CellularComponent SCF-Rcy1/Pof6 ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe). go-plus.json http://purl.obolibrary.org/obo/GO_0097667 PO:0025541 biolink:OntologyClass bundle sheath cell A ground tissue cell (PO:0000076) that is part of a bundle sheath (PO:0006023). go-plus.json celula de la vaina del haz vascular (Spanish, exact)|維管束鞘細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025541 GO:0048626 biolink:BiologicalProcess myoblast fate specification The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0048626 CHEBI:63571 biolink:ChemicalSubstance trisaccharide derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_63571 UBERON:0035044 biolink:AnatomicalEntity olfactory cortex layer 3 Deepest layer of olfactory cortex go-plus.json http://purl.obolibrary.org/obo/UBERON_0035044 GO:0048625 biolink:BiologicalProcess myoblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0048625 GO:0048624 biolink:BiologicalProcess plantlet formation on parent plant The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed. go-plus.json vegetative vivipary|vivipary http://purl.obolibrary.org/obo/GO_0048624 GO:0048623 biolink:BiologicalProcess seed germination on parent plant The process in which a seed germinates before being shed from the parent plant. go-plus.json non-vegetative vivipary|vivipary|pre-harvest sprouting http://purl.obolibrary.org/obo/GO_0048623 GO:0048622 biolink:BiologicalProcess obsolete reproductive sporulation OBSOLETE. The formation of reproductive spores. go-plus.json reproductive sporulation http://purl.obolibrary.org/obo/GO_0048622 CHEBI:63576 biolink:ChemicalSubstance maltose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63576 chebi_ph7_3 UBERON:0035049 biolink:AnatomicalEntity excretory duct of salivary gland Any of the interlobular excretory ducts of a salivary gland which are found in the connective tissue septa and formed by the union of several intralobular striated (secretory) ducts[MP,generalized]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035049 GO:0048621 biolink:BiologicalProcess post-embryonic digestive tract morphogenesis The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. go-plus.json post-embryonic gut morphogenesis http://purl.obolibrary.org/obo/GO_0048621 GO:0048620 biolink:BiologicalProcess post-embryonic hindgut morphogenesis The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase. go-plus.json http://purl.obolibrary.org/obo/GO_0048620 CHEBI:63573 biolink:ChemicalSubstance guanyl deoxyribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_63573 CHEBI:63579 biolink:ChemicalSubstance 18-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_63579 GO:0048629 biolink:BiologicalProcess trichome patterning The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes. go-plus.json trichome spacing|trichome pattern formation|trichome pattern specification|trichome pattern biosynthesis|trichome distribution http://purl.obolibrary.org/obo/GO_0048629 GO:0048628 biolink:BiologicalProcess myoblast maturation A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0048628 GO:0048627 biolink:BiologicalProcess myoblast development The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0048627 PO:0025530 biolink:OntologyClass reproductive shoot system development stage A shoot system development stage (PO:0025527) that has as primary participant a reproductive shoot system (PO:0025082). go-plus.json http://purl.obolibrary.org/obo/PO_0025530 SO:0000673 biolink:SequenceFeature transcript An RNA synthesized on a DNA or RNA template by an RNA polymerase. http://en.wikipedia.org/wiki/RNA go-plus.json INSDC_feature:misc_RNA http://purl.obolibrary.org/obo/SO_0000673 SOFA UBERON:0035050 biolink:AnatomicalEntity excretory duct go-plus.json http://purl.obolibrary.org/obo/UBERON_0035050 UBERON:0035053 biolink:AnatomicalEntity interlobular duct of salivary gland go-plus.json http://purl.obolibrary.org/obo/UBERON_0035053 GO:0048637 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048637 CHEBI:63582 biolink:ChemicalSubstance 1-palmitoylglycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63582 chebi_ph7_3 GO:0048636 biolink:BiologicalProcess positive regulation of muscle organ development Any process that activates, maintains or increases the rate of muscle development. go-plus.json up regulation of muscle development|upregulation of muscle development|stimulation of muscle development|up-regulation of muscle development|activation of muscle development http://purl.obolibrary.org/obo/GO_0048636 GO:0048635 biolink:BiologicalProcess negative regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. go-plus.json downregulation of muscle development|down regulation of muscle development|inhibition of muscle development|down-regulation of muscle development http://purl.obolibrary.org/obo/GO_0048635 CHEBI:63580 biolink:ChemicalSubstance ribavirin go-plus.json http://purl.obolibrary.org/obo/CHEBI_63580 chebi_ph7_3 GO:0048634 biolink:BiologicalProcess regulation of muscle organ development Any process that modulates the frequency, rate or extent of muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0048634 GO:0048633 biolink:BiologicalProcess positive regulation of skeletal muscle tissue growth Any process that activates, maintains or increases the rate of skeletal muscle growth. go-plus.json upregulation of skeletal muscle growth|stimulation of skeletal muscle growth|up-regulation of skeletal muscle growth|activation of skeletal muscle growth|up regulation of skeletal muscle growth http://purl.obolibrary.org/obo/GO_0048633 GO:0048632 biolink:BiologicalProcess negative regulation of skeletal muscle tissue growth Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. go-plus.json downregulation of skeletal muscle growth|down regulation of skeletal muscle growth|inhibition of skeletal muscle growth|down-regulation of skeletal muscle growth http://purl.obolibrary.org/obo/GO_0048632 CHEBI:87531 biolink:ChemicalSubstance prenyl-FMNH2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_87531 GO:0048631 biolink:BiologicalProcess regulation of skeletal muscle tissue growth Any process that modulates the frequency, rate or extent of skeletal muscle growth. go-plus.json http://purl.obolibrary.org/obo/GO_0048631 GO:0048630 biolink:BiologicalProcess skeletal muscle tissue growth The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. go-plus.json http://purl.obolibrary.org/obo/GO_0048630 CHEBI:87538 biolink:ChemicalSubstance 16alpha-hydroxydehydroepiandrosterone 3-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87538 chebi_ph7_3 GO:0048639 biolink:BiologicalProcess positive regulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. go-plus.json up-regulation of developmental growth|activation of developmental growth|up regulation of developmental growth|upregulation of developmental growth|stimulation of developmental growth http://purl.obolibrary.org/obo/GO_0048639 PO:0025528 biolink:OntologyClass bud development stage A shoot system development stage (PO:0025527) that has as primary participant a bud (PO:0009006). go-plus.json http://purl.obolibrary.org/obo/PO_0025528 GO:0048638 biolink:BiologicalProcess regulation of developmental growth Any process that modulates the frequency, rate or extent of developmental growth. go-plus.json http://purl.obolibrary.org/obo/GO_0048638 PO:0025527 biolink:OntologyClass shoot system development stage A collective plant organ structure development stage (PO:0025338) that begins with the onset of the plant organ development stage (PO:0025339) and ends with either gametophyte senescent stage (PO:0025343) or sporophyte senescent stage (PO:0007017) or death. go-plus.json http://purl.obolibrary.org/obo/PO_0025527 PO:0025526 biolink:OntologyClass body cell A spermatogenous cell (PO:0025525) of the microgametophyte (PO:0025280) that divides to produce a vegetative cell (PO:0020099) and the pollen sperm cell (PO:0025121). go-plus.json gymnosperm generative cell (exact) http://purl.obolibrary.org/obo/PO_0025526 PO:0025525 biolink:OntologyClass spermatogenous cell A native plant cell (PO:0025606) that gives rise to one or more plant sperm cells (PO:0000084). go-plus.json http://purl.obolibrary.org/obo/PO_0025525 GO:0048640 biolink:BiologicalProcess negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. go-plus.json down regulation of developmental growth|inhibition of developmental growth|down-regulation of developmental growth|downregulation of developmental growth http://purl.obolibrary.org/obo/GO_0048640 GO:1903809 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903809 GO:1903808 biolink:BiologicalProcess L-tyrosine import across plasma membrane The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-tyrosine import|L-tyrosine uptake|L-tyrosine import into cell http://purl.obolibrary.org/obo/GO_1903808 GO:1903807 biolink:BiologicalProcess L-threonine import across plasma membrane The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-threonine import into cell|L-threonine import|L-threonine uptake http://purl.obolibrary.org/obo/GO_1903807 GO:1903806 biolink:BiologicalProcess L-isoleucine import across plasma membrane The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-isoleucine import into cell|isoleucine import|L-isoleucine import http://purl.obolibrary.org/obo/GO_1903806 GO:1903805 biolink:BiologicalProcess L-valine import across plasma membrane The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json valine import|L-valine import into cell http://purl.obolibrary.org/obo/GO_1903805 CHEBI:63590 biolink:ChemicalSubstance 18-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63590 chebi_ph7_3 GO:1903804 biolink:BiologicalProcess glycine import across plasma membrane The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json glycine import|glycine import into cell http://purl.obolibrary.org/obo/GO_1903804 PR:000049989 biolink:Protein glucagon-like receptor A secretin-like G-protein coupled receptor that is a translation product of the human GHRHR, GIPR, GLP1R, GLP2R, GCGR, or SCTR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json glucagon receptor http://purl.obolibrary.org/obo/PR_000049989 GO:1903803 biolink:BiologicalProcess L-glutamine import across plasma membrane The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-glutamine import|L-glutamine uptake|L-glutamine import into cell http://purl.obolibrary.org/obo/GO_1903803 GO:1903802 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903802 GO:1903801 biolink:BiologicalProcess L-leucine import across plasma membrane The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-leucine uptake|L-leucine import into cell|leucine uptake|L-leucine import|leucine import http://purl.obolibrary.org/obo/GO_1903801 GO:0048648 biolink:BiologicalProcess caste determination The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects. go-plus.json http://purl.obolibrary.org/obo/GO_0048648 CHEBI:63594 biolink:ChemicalSubstance 1-ribosyltriazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_63594 GO:1903800 biolink:BiologicalProcess positive regulation of production of miRNAs involved in gene silencing by miRNA Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA. go-plus.json positive regulation of microRNA biogenesis|upregulation of miRNA biogenesis|upregulation of gene silencing by miRNA, production of miRNAs|up-regulation of microRNA-mediated gene silencing, production of microRNAs|up-regulation of microRNA metabolism|activation of microRNA metabolic process|upregulation of production of microRNAs involved in gene silencing by microRNA|up-regulation of production of miRNAs involved in gene silencing by miRNA|activation of production of miRNAs involved in gene silencing by miRNA|activation of microRNA biogenesis|up-regulation of miRNA-mediated gene silencing, production of miRNAs|positive regulation of microRNA metabolic process|upregulation of microRNA biosynthesis|upregulation of miRNA processing|upregulation of microRNA biosynthetic process|up regulation of microRNA metabolic process|up-regulation of miRNA biogenesis|upregulation of microRNA-mediated gene silencing, production of microRNAs|up regulation of gene silencing by miRNA, production of miRNAs|upregulation of microRNA metabolism|up-regulation of microRNA biogenesis|activation of production of microRNAs involved in gene silencing by microRNA|activation of gene silencing by miRNA, production of miRNAs|up-regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of gene silencing by miRNA, production of miRNAs|upregulation of miRNA-mediated gene silencing, production of miRNAs|activation of miRNA biogenesis|up regulation of production of miRNAs involved in gene silencing by miRNA|up-regulation of miRNA processing|activation of miRNA processing|up regulation of microRNA biosynthetic process|up regulation of microRNA biosynthesis|upregulation of microRNA metabolic process|upregulation of microRNA biogenesis|positive regulation of microRNA biosynthesis|up regulation of microRNA-mediated gene silencing, production of microRNAs|positive regulation of microRNA biosynthetic process|positive regulation of miRNA biogenesis|activation of microRNA-mediated gene silencing, production of microRNAs|up regulation of microRNA metabolism|up regulation of miRNA biogenesis|positive regulation of microRNA-mediated gene silencing, production of microRNAs|positive regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of microRNA metabolism|up-regulation of gene silencing by miRNA, production of miRNAs|up regulation of miRNA-mediated gene silencing, production of miRNAs|activation of microRNA biosynthetic process|activation of microRNA biosynthesis|activation of miRNA-mediated gene silencing, production of miRNAs|up regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of miRNA-mediated gene silencing, production of miRNAs|upregulation of production of miRNAs involved in gene silencing by miRNA|activation of microRNA metabolism|positive regulation of miRNA processing|up-regulation of microRNA metabolic process|up regulation of miRNA processing|up regulation of microRNA biogenesis|up-regulation of microRNA biosynthetic process|up-regulation of microRNA biosynthesis http://purl.obolibrary.org/obo/GO_1903800 GO:0048647 biolink:BiologicalProcess polyphenic determination The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues. go-plus.json http://purl.obolibrary.org/obo/GO_0048647 CHEBI:63593 biolink:ChemicalSubstance 1-glycosyltriazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_63593 GO:0048646 biolink:BiologicalProcess anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. go-plus.json formation of an anatomical structure involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048646 goslim_chembl|goslim_generic CHEBI:63592 biolink:ChemicalSubstance maltose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63592 GO:0048645 biolink:BiologicalProcess animal organ formation The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. go-plus.json initiation of an animal organ primordium|animal organ primordium initiation http://purl.obolibrary.org/obo/GO_0048645 GO:0048644 biolink:BiologicalProcess muscle organ morphogenesis The process in which the anatomical structures of muscle are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048644 GO:0048643 biolink:BiologicalProcess positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle tissue development. go-plus.json up-regulation of skeletal muscle development|upregulation of skeletal muscle development|up regulation of skeletal muscle development|activation of skeletal muscle development|stimulation of skeletal muscle development http://purl.obolibrary.org/obo/GO_0048643 GO:0048642 biolink:BiologicalProcess negative regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. go-plus.json inhibition of skeletal muscle development|down regulation of skeletal muscle development|downregulation of skeletal muscle development|down-regulation of skeletal muscle development http://purl.obolibrary.org/obo/GO_0048642 GO:0048641 biolink:BiologicalProcess regulation of skeletal muscle tissue development Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. go-plus.json http://purl.obolibrary.org/obo/GO_0048641 GO:0048649 biolink:BiologicalProcess caste determination, influence by genetic factors The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects. go-plus.json http://purl.obolibrary.org/obo/GO_0048649 SO:0000699 biolink:SequenceFeature junction A sequence_feature with an extent of zero. go-plus.json boundary|breakpoint http://purl.obolibrary.org/obo/SO_0000699 SOFA GO:0048651 biolink:BiologicalProcess polyphenic determination, influence by environmental factors The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues. go-plus.json http://purl.obolibrary.org/obo/GO_0048651 GO:1903819 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic cytokinesis checkpoint OBSOLETE. Any detection of stimulus that is involved in a mitotic cytokinesis checkpoint. go-plus.json stimulus sensing involved in mitotic cytokinesis checkpoint|perception of stimulus involved in mitotic cytokinesis checkpoint|stimulus detection involved in mitotic cytokinesis checkpoint http://purl.obolibrary.org/obo/GO_1903819 GO:0048650 biolink:BiologicalProcess caste determination, influence by environmental factors The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects. go-plus.json http://purl.obolibrary.org/obo/GO_0048650 GO:1903818 biolink:BiologicalProcess positive regulation of voltage-gated potassium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity. go-plus.json upregulation of voltage-sensitive potassium channel|activation of voltage-gated potassium channel activity|upregulation of voltage gated potassium channel activity|up-regulation of voltage-dependent potassium channel activity|activation of voltage-dependent potassium channel activity|up-regulation of voltage-gated potassium ion channel activity|activation of voltage-gated potassium ion channel activity|up regulation of voltage-sensitive potassium channel|positive regulation of voltage-sensitive potassium channel|up-regulation of voltage gated potassium channel activity|activation of voltage-sensitive potassium channel|up regulation of voltage-gated potassium channel activity|activation of voltage gated potassium channel activity|positive regulation of voltage-dependent potassium channel activity|positive regulation of voltage-gated potassium ion channel activity|up regulation of voltage-dependent potassium channel activity|up regulation of voltage-gated potassium ion channel activity|upregulation of voltage-gated potassium channel activity|up-regulation of voltage-sensitive potassium channel|positive regulation of voltage gated potassium channel activity|up regulation of voltage gated potassium channel activity|upregulation of voltage-dependent potassium channel activity|upregulation of voltage-gated potassium ion channel activity|up-regulation of voltage-gated potassium channel activity http://purl.obolibrary.org/obo/GO_1903818 GO:1903817 biolink:BiologicalProcess negative regulation of voltage-gated potassium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity. go-plus.json down regulation of voltage gated potassium channel activity|inhibition of voltage gated potassium channel activity|down regulation of voltage-sensitive potassium channel|down-regulation of voltage-gated potassium channel activity|downregulation of voltage-sensitive potassium channel|negative regulation of voltage-dependent potassium channel activity|down-regulation of voltage-dependent potassium channel activity|negative regulation of voltage-gated potassium ion channel activity|down-regulation of voltage-gated potassium ion channel activity|downregulation of voltage-gated potassium channel activity|negative regulation of voltage-sensitive potassium channel|down-regulation of voltage-sensitive potassium channel|down-regulation of voltage gated potassium channel activity|negative regulation of voltage gated potassium channel activity|down regulation of voltage-gated potassium channel activity|downregulation of voltage-dependent potassium channel activity|inhibition of voltage-gated potassium channel activity|downregulation of voltage-gated potassium ion channel activity|inhibition of voltage-sensitive potassium channel|down regulation of voltage-dependent potassium channel activity|down regulation of voltage-gated potassium ion channel activity|inhibition of voltage-dependent potassium channel activity|downregulation of voltage gated potassium channel activity|inhibition of voltage-gated potassium ion channel activity http://purl.obolibrary.org/obo/GO_1903817 GO:1903816 biolink:BiologicalProcess positive regulation of collecting lymphatic vessel constriction Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction. go-plus.json up-regulation of lymphatic vessel myogenic constriction|activation of lymphatic vessel myogenic constriction|up-regulation of collecting lymphatic vessel constriction|activation of collecting lymphatic vessel constriction|positive regulation of lymphatic vessel myogenic constriction|up regulation of lymphatic vessel myogenic constriction|up regulation of collecting lymphatic vessel constriction|upregulation of lymphatic vessel myogenic constriction|upregulation of collecting lymphatic vessel constriction http://purl.obolibrary.org/obo/GO_1903816 UBERON:0035074 biolink:AnatomicalEntity duct of apocrine sweat gland go-plus.json ductal part of apocrine sweat gland http://purl.obolibrary.org/obo/UBERON_0035074 GO:1903815 biolink:BiologicalProcess negative regulation of collecting lymphatic vessel constriction Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction. go-plus.json down-regulation of lymphatic vessel myogenic constriction|negative regulation of lymphatic vessel myogenic constriction|down-regulation of collecting lymphatic vessel constriction|downregulation of lymphatic vessel myogenic constriction|downregulation of collecting lymphatic vessel constriction|down regulation of lymphatic vessel myogenic constriction|inhibition of lymphatic vessel myogenic constriction|down regulation of collecting lymphatic vessel constriction|inhibition of collecting lymphatic vessel constriction http://purl.obolibrary.org/obo/GO_1903815 GO:1903814 biolink:BiologicalProcess regulation of collecting lymphatic vessel constriction Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction. go-plus.json regulation of lymphatic vessel myogenic constriction http://purl.obolibrary.org/obo/GO_1903814 UBERON:0035075 biolink:AnatomicalEntity thymus subunit go-plus.json lobe or lobule of thymus http://purl.obolibrary.org/obo/UBERON_0035075 GO:1903813 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903813 GO:1903812 biolink:BiologicalProcess L-serine import across plasma membrane The directed movement of L-serine into a cell. go-plus.json L-serine import into cell http://purl.obolibrary.org/obo/GO_1903812 GO:0048659 biolink:BiologicalProcess smooth muscle cell proliferation The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. go-plus.json SMC proliferation http://purl.obolibrary.org/obo/GO_0048659 PR:000049997 biolink:Protein leukotriene receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human LTB4R, LTB4R2, CYSLTR1, CYSLTR2, or OXER1 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000049997 GO:1903811 biolink:BiologicalProcess L-asparagine import across plasma membrane The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-asparagine import into cell|asparagine import http://purl.obolibrary.org/obo/GO_1903811 GO:0048658 biolink:BiologicalProcess anther wall tapetum development The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure. go-plus.json tapetal layer development|tapetum development http://purl.obolibrary.org/obo/GO_0048658 GO:1903810 biolink:BiologicalProcess L-histidine import across plasma membrane The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-histidine import|histidine import|L-histidine import into cell http://purl.obolibrary.org/obo/GO_1903810 GO:0048657 biolink:BiologicalProcess anther wall tapetum cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature. go-plus.json tapetal cell differentiation http://purl.obolibrary.org/obo/GO_0048657 GO:0048656 biolink:BiologicalProcess anther wall tapetum formation The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature. go-plus.json tapetal layer formation|tapetum formation http://purl.obolibrary.org/obo/GO_0048656 GO:0048655 biolink:BiologicalProcess anther wall tapetum morphogenesis The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature. go-plus.json tapetal layer morphogenesis|differentiation of tapetal layer|tapetum morphogenesis http://purl.obolibrary.org/obo/GO_0048655 GO:0048654 biolink:BiologicalProcess anther morphogenesis The process in which the anatomical structures of the anther are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0048654 GO:0048653 biolink:BiologicalProcess anther development The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0048653 PR:000049994 biolink:Protein histamine receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human HRH1 to HRH4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000049994 GO:0048652 biolink:BiologicalProcess polyphenic determination, influence by genetic factors The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues. go-plus.json http://purl.obolibrary.org/obo/GO_0048652 GO:0048662 biolink:BiologicalProcess negative regulation of smooth muscle cell proliferation Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. go-plus.json down-regulation of smooth muscle cell proliferation|downregulation of smooth muscle cell proliferation|down regulation of smooth muscle cell proliferation|inhibition of smooth muscle cell proliferation|negative regulation of SMC proliferation http://purl.obolibrary.org/obo/GO_0048662 GO:0048661 biolink:BiologicalProcess positive regulation of smooth muscle cell proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation. go-plus.json up regulation of smooth muscle cell proliferation|positive regulation of SMC proliferation|upregulation of smooth muscle cell proliferation|stimulation of smooth muscle cell proliferation|up-regulation of smooth muscle cell proliferation|activation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048661 GO:1903829 biolink:BiologicalProcess positive regulation of cellular protein localization Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. go-plus.json up regulation of channel localizer activity|upregulation of cellular protein localization|up regulation of cellular protein localisation|positive regulation of cellular protein localisation|activation of cellular protein localisation|upregulation of channel localizer activity|up regulation of cellular protein localization|activation of cellular protein localization|up-regulation of cellular protein localisation|up-regulation of channel localizer activity|activation of channel localizer activity|up-regulation of cellular protein localization|upregulation of cellular protein localisation|positive regulation of channel localizer activity http://purl.obolibrary.org/obo/GO_1903829 GO:0048660 biolink:BiologicalProcess regulation of smooth muscle cell proliferation Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. go-plus.json regulation of SMC proliferation http://purl.obolibrary.org/obo/GO_0048660 GO:1903828 biolink:BiologicalProcess negative regulation of cellular protein localization Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. go-plus.json downregulation of cellular protein localisation|downregulation of channel localizer activity|down regulation of cellular protein localization|down regulation of channel localizer activity|downregulation of cellular protein localization|negative regulation of cellular protein localisation|down-regulation of cellular protein localisation|inhibition of channel localizer activity|inhibition of cellular protein localisation|down-regulation of cellular protein localization|inhibition of cellular protein localization|down-regulation of channel localizer activity|negative regulation of channel localizer activity|down regulation of cellular protein localisation http://purl.obolibrary.org/obo/GO_1903828 GO:1903827 biolink:BiologicalProcess regulation of cellular protein localization Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. go-plus.json regulation of channel localizer activity|regulation of cellular protein localisation http://purl.obolibrary.org/obo/GO_1903827 GO:1903826 biolink:BiologicalProcess arginine transmembrane transport The directed movement of arginine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903826 GO:1903825 biolink:BiologicalProcess organic acid transmembrane transport The process in which an organic acid is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903825 GO:1903824 biolink:BiologicalProcess negative regulation of telomere single strand break repair Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair. go-plus.json downregulation of telomere single strand break repair|down regulation of single strand break repair in telomere|down regulation of telomere SSBR|inhibition of single strand break repair in telomere|downregulation of telomere SSBR|down-regulation of telomere single strand break repair|down regulation of telomere single-strand break repair|downregulation of telomere single-strand break repair|down-regulation of telomere SSBR|down-regulation of telomeric single strand break repair|negative regulation of telomere SSBR|negative regulation of telomeric single strand break repair|inhibition of telomere single strand break repair|negative regulation of single strand break repair in telomere|down-regulation of single strand break repair in telomere|negative regulation of telomere single-strand break repair|down-regulation of telomere single-strand break repair|downregulation of telomeric single strand break repair|inhibition of telomere SSBR|down regulation of telomeric single strand break repair|inhibition of telomeric single strand break repair|down regulation of telomere single strand break repair|inhibition of telomere single-strand break repair|downregulation of single strand break repair in telomere http://purl.obolibrary.org/obo/GO_1903824 GO:1903823 biolink:BiologicalProcess telomere single strand break repair Single strand break repair that takes place in a telomere. go-plus.json telomere SSBR|telomere single-strand break repair|single strand break repair in telomere|telomeric single strand break repair http://purl.obolibrary.org/obo/GO_1903823 GO:0048669 biolink:BiologicalProcess collateral sprouting in absence of injury The process in which outgrowths develop from the axons of intact undamaged neurons. go-plus.json http://purl.obolibrary.org/obo/GO_0048669 GO:1903822 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903822 GO:1903821 biolink:BiologicalProcess obsolete detection of stimulus involved in morphogenesis checkpoint OBSOLETE. Any detection of stimulus that is involved in morphogenesis checkpoint. go-plus.json perception of stimulus involved in septin checkpoint|detection of stimulus involved in septin checkpoint|stimulus sensing involved in septin checkpoint|stimulus detection involved in morphogenesis checkpoint|stimulus detection involved in septin checkpoint|stimulus sensing involved in morphogenesis checkpoint|perception of stimulus involved in morphogenesis checkpoint http://purl.obolibrary.org/obo/GO_1903821 GO:0048668 biolink:BiologicalProcess collateral sprouting The process in which outgrowths develop from the shafts of existing axons. go-plus.json axon branching http://purl.obolibrary.org/obo/GO_0048668 GO:0048667 biolink:BiologicalProcess cell morphogenesis involved in neuron differentiation The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. go-plus.json neuron morphogenesis involved in differentiation http://purl.obolibrary.org/obo/GO_0048667 GO:1903820 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903820 CHEBI:87584 biolink:ChemicalSubstance N(2)-acyl-L-glutaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87584 chebi_ph7_3 GO:0048666 biolink:BiologicalProcess neuron development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0048666 GO:0048665 biolink:BiologicalProcess neuron fate specification The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0048665 GO:0048664 biolink:BiologicalProcess neuron fate determination The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0048664 GO:0048663 biolink:BiologicalProcess neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron. go-plus.json neuron lineage restriction|neuronal lineage restriction http://purl.obolibrary.org/obo/GO_0048663 NCBITaxon:2836 biolink:OrganismalEntity Bacillariophyta go-plus.json algae|diatoms|Diatomeae|Diatomea|Diatomophyceae|diatoms|bacillariophytes http://purl.obolibrary.org/obo/NCBITaxon_2836 GO:0034098 biolink:CellularComponent VCP-NPL4-UFD1 AAA ATPase complex A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). go-plus.json Cdc48p-Npl4p-Ufd1p AAA ATPase complex|p97-Ufd1-Npl4 complex http://purl.obolibrary.org/obo/GO_0034098 CL:1001588 biolink:Cell colon glandular cell Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. go-plus.json colon glandular cells http://purl.obolibrary.org/obo/CL_1001588 CL:1001587 biolink:Cell uterine cervix glandular cell Glandular cell of uterine cervix epithelium. go-plus.json cervix glandular cell|cervix, uterine glandular cell|cervix, uterine glandular cells http://purl.obolibrary.org/obo/CL_1001587 GO:0034097 biolink:BiologicalProcess response to cytokine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. go-plus.json response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0034097 CL:1001586 biolink:Cell mammary gland glandular cell Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts. go-plus.json mammary glandular cell|breast glandular cell|breast glandular cells http://purl.obolibrary.org/obo/CL_1001586 GO:0034096 biolink:BiologicalProcess positive regulation of maintenance of meiotic sister chromatid cohesion Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034096 GO:0034095 biolink:BiologicalProcess negative regulation of maintenance of meiotic sister chromatid cohesion Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034095 GO:0034094 biolink:BiologicalProcess regulation of maintenance of meiotic sister chromatid cohesion Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034094 GO:0034093 biolink:BiologicalProcess positive regulation of maintenance of sister chromatid cohesion Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0034093 GO:0034092 biolink:BiologicalProcess negative regulation of maintenance of sister chromatid cohesion Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0034092 CL:1001582 biolink:Cell lateral ventricle neuron Neuron of lateral ventricle. go-plus.json lateral ventricle neuronal cell|lateral ventricle neural cell|lateral ventricle neuronal cells http://purl.obolibrary.org/obo/CL_1001582 CL:1001581 biolink:Cell lateral ventricle glial cell Glial cell of lateral ventricle. go-plus.json lateral ventricle glial cells http://purl.obolibrary.org/obo/CL_1001581 GO:0034091 biolink:BiologicalProcess regulation of maintenance of sister chromatid cohesion Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained. go-plus.json http://purl.obolibrary.org/obo/GO_0034091 CL:1001580 biolink:Cell hippocampus glial cell Glial cell of hippocampus. go-plus.json hippocampus glial cells|hippocampus neuroglial cell|hippocampal glial cell http://purl.obolibrary.org/obo/CL_1001580 PR:000011387 biolink:Protein neuropeptide Y A protein that is a translation product of the human NPY gene or a 1:1 ortholog thereof. go-plus.json NPY http://purl.obolibrary.org/obo/PR_000011387 GO:0034099 biolink:CellularComponent luminal surveillance complex A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0034099 GO:0048673 biolink:BiologicalProcess collateral sprouting of intact axon in response to injury The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input. go-plus.json http://purl.obolibrary.org/obo/GO_0048673 GO:0048672 biolink:BiologicalProcess positive regulation of collateral sprouting Any process that activates or increases the frequency, rate or extent of collateral sprouting. go-plus.json up regulation of collateral sprouting|upregulation of collateral sprouting|stimulation of collateral sprouting|up-regulation of collateral sprouting|activation of collateral sprouting http://purl.obolibrary.org/obo/GO_0048672 GO:0048671 biolink:BiologicalProcess negative regulation of collateral sprouting Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting. go-plus.json downregulation of collateral sprouting|down regulation of collateral sprouting|inhibition of collateral sprouting|down-regulation of collateral sprouting http://purl.obolibrary.org/obo/GO_0048671 GO:1903839 biolink:BiologicalProcess positive regulation of mRNA 3'-UTR binding Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding. go-plus.json activation of mRNA 3'-UTR binding|upregulation of mRNA 3' UTR binding|up-regulation of mRNA 3'-UTR binding|up regulation of mRNA 3' UTR binding|positive regulation of mRNA 3' UTR binding|activation of mRNA 3' UTR binding|upregulation of mRNA 3'-UTR binding|up-regulation of mRNA 3' UTR binding|up regulation of mRNA 3'-UTR binding http://purl.obolibrary.org/obo/GO_1903839 GO:0048670 biolink:BiologicalProcess regulation of collateral sprouting Any process that modulates the frequency, rate or extent of collateral sprouting. go-plus.json http://purl.obolibrary.org/obo/GO_0048670 GO:1903838 biolink:BiologicalProcess negative regulation of mRNA 3'-UTR binding Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding. go-plus.json down-regulation of mRNA 3'-UTR binding|inhibition of mRNA 3'-UTR binding|down regulation of mRNA 3' UTR binding|downregulation of mRNA 3' UTR binding|down-regulation of mRNA 3' UTR binding|negative regulation of mRNA 3' UTR binding|down regulation of mRNA 3'-UTR binding|downregulation of mRNA 3'-UTR binding|inhibition of mRNA 3' UTR binding http://purl.obolibrary.org/obo/GO_1903838 GO:1903837 biolink:BiologicalProcess regulation of mRNA 3'-UTR binding Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding. go-plus.json regulation of mRNA 3' UTR binding http://purl.obolibrary.org/obo/GO_1903837 GO:1903835 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903835 GO:1903834 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903834 GO:0034090 biolink:BiologicalProcess maintenance of meiotic sister chromatid cohesion The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034090 GO:1903833 biolink:BiologicalProcess positive regulation of cellular response to amino acid starvation Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation. go-plus.json upregulation of cellular response to amino acid starvation|up-regulation of cellular response to amino acid starvation|activation of cellular response to amino acid starvation|up regulation of cellular response to amino acid starvation http://purl.obolibrary.org/obo/GO_1903833 CHEBI:87571 biolink:ChemicalSubstance 6beta-hydroxyandrost-4-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_87571 chebi_ph7_3 GO:0048679 biolink:BiologicalProcess regulation of axon regeneration Any process that modulates the frequency, rate or extent of axon regeneration. go-plus.json http://purl.obolibrary.org/obo/GO_0048679 GO:1903832 biolink:BiologicalProcess regulation of cellular response to amino acid starvation Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1903832 GO:0048678 biolink:BiologicalProcess response to axon injury Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0048678 GO:1903831 biolink:BiologicalProcess signal transduction involved in cellular response to ammonium ion Any signal transduction that is involved in cellular response to ammonium ion. go-plus.json signalling pathway involved in cellular response to ammonium ion|signaling pathway involved in cellular response to ammonium ion|signalling cascade involved in cellular response to ammonium ion|signaling cascade involved in cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_1903831 GO:0048677 biolink:BiologicalProcess axon extension involved in regeneration Long distance growth of a single axon process involved in regeneration of the neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0048677 GO:1903830 biolink:BiologicalProcess magnesium ion transmembrane transport The directed movement of magnesium ion across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903830 UBERON:0035016 biolink:AnatomicalEntity tactile mechanoreceptor go-plus.json contact receptor http://purl.obolibrary.org/obo/UBERON_0035016 GO:0048676 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0048676 CL:1001579 biolink:Cell cerebral cortex glial cell Glial cell of cerebral cortex. go-plus.json brain cortex glial cell|cerebral cortex glial cells|cerebrum cortex glial cell http://purl.obolibrary.org/obo/CL_1001579 GO:0048675 biolink:BiologicalProcess axon extension Long distance growth of a single axon process involved in cellular development. go-plus.json axon extension involved in development http://purl.obolibrary.org/obo/GO_0048675 UBERON:0035018 biolink:AnatomicalEntity thermoreceptor Cellular receptors which mediate the sense of temperature. Thermoreceptors in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and NOCICEPTORS which detect cold or heat extreme enough to cause pain. go-plus.json thermoreceptor http://purl.obolibrary.org/obo/UBERON_0035018 UBERON:0035017 biolink:AnatomicalEntity nociceptor Peripheral receptors for pain. Nociceptors include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All nociceptors are free nerve endings. go-plus.json nociceptor|pain receptor http://purl.obolibrary.org/obo/UBERON_0035017 GO:0048674 biolink:BiologicalProcess collateral sprouting of injured axon The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons. go-plus.json http://purl.obolibrary.org/obo/GO_0048674 CL:1001578 biolink:Cell vagina squamous cell Squamous cell of vaginal epithelium. go-plus.json vaginal squamous epithelial cell|vaginal squamous cell|vagina squamous epithelial cells|vagina squamous epithelial cell http://purl.obolibrary.org/obo/CL_1001578 GO:0034087 biolink:BiologicalProcess establishment of mitotic sister chromatid cohesion The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034087 GO:0034086 biolink:BiologicalProcess maintenance of sister chromatid cohesion The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate. go-plus.json http://purl.obolibrary.org/obo/GO_0034086 CL:1001575 biolink:Cell uterine cervix squamous cell Squamous cell of uterine cervix epithelium. go-plus.json uterine cervix squamous epithelial cells|cervix squamous epithelial cell|uterine cervix squamous epithelial cell|cervix, uterine squamous epithelial cells|cervix squamous cell http://purl.obolibrary.org/obo/CL_1001575 GO:0034085 biolink:BiologicalProcess establishment of sister chromatid cohesion The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase. go-plus.json http://purl.obolibrary.org/obo/GO_0034085 GO:0034084 biolink:MolecularActivity steryl deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol. go-plus.json sterol deacetylase activity http://purl.obolibrary.org/obo/GO_0034084 GO:0097608 biolink:CellularComponent transverse flagellum A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum. go-plus.json transverse cilium http://purl.obolibrary.org/obo/GO_0097608 GO:0034083 biolink:CellularComponent type III polyketide synthase complex A polyketide synthase complex that consists of two identical ketosynthase polypeptides. go-plus.json type III PKS complex|type III polyketide synthase|type III PKS http://purl.obolibrary.org/obo/GO_0034083 CL:1001572 biolink:Cell colon endothelial cell A vascular endothelial cell found in colon blood vessels. go-plus.json colonic endothelial cell|colon endothelial cells http://purl.obolibrary.org/obo/CL_1001572 GO:0034082 biolink:CellularComponent type II polyketide synthase complex A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction. go-plus.json type II PKS complex|type II polyketide synthase|type II PKS http://purl.obolibrary.org/obo/GO_0034082 GO:0097607 biolink:BiologicalProcess obsolete negative regulation of nuclear envelope permeability OBSOLETE. Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope. go-plus.json negative regulation of nuclear membrane permeability http://purl.obolibrary.org/obo/GO_0097607 GO:0034081 biolink:CellularComponent polyketide synthase complex A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones. go-plus.json PKS|PKS complex http://purl.obolibrary.org/obo/GO_0034081 CL:1001571 biolink:Cell hippocampal pyramidal neuron A pyramidal neuron of the hippocampus. go-plus.json hippocampus (CA) pyramidal cell|hippocampus (CA) pyramidal neuron http://purl.obolibrary.org/obo/CL_1001571 GO:0034080 biolink:BiologicalProcess CENP-A containing nucleosome assembly The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. go-plus.json centromere specific nucleosome exchange|DNA replication-independent nucleosome assembly at centromere|CENP-A loading|centromere-specific histone exchange|CENP-A deposition|CENP-A containing nucleosome assembly at centromere|CenH3-containing nucleosome assembly at centromere|centromeric DNA replication-independent nucleosome assembly http://purl.obolibrary.org/obo/GO_0034080 GO:0097609 biolink:CellularComponent longitudinal flagellum A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus. go-plus.json longitudinal cilium http://purl.obolibrary.org/obo/GO_0097609 GO:0097604 biolink:MolecularActivity temperature-gated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism). go-plus.json heat-activated cation channel activity|temperature-activated cation channel activity|temperature gated cation channel activity|temperature-dependent cation channel activity http://purl.obolibrary.org/obo/GO_0097604 GO:0097603 biolink:MolecularActivity temperature-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism). go-plus.json temperature gated ion channel activity|heat-activated ion channel activity|temperature-activated ion channel activity|temperature-dependent ion channel activity http://purl.obolibrary.org/obo/GO_0097603 GO:0097606 biolink:BiologicalProcess obsolete positive regulation of nuclear envelope permeability OBSOLETE. Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope. go-plus.json positive regulation of nuclear membrane permeability http://purl.obolibrary.org/obo/GO_0097606 GO:0097605 biolink:BiologicalProcess obsolete regulation of nuclear envelope permeability OBSOLETE. Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope. go-plus.json regulation of nuclear membrane permeability http://purl.obolibrary.org/obo/GO_0097605 GO:0097600 biolink:MolecularActivity exoxylanase activity A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains. go-plus.json http://purl.obolibrary.org/obo/GO_0097600 GO:0097602 biolink:MolecularActivity cullin family protein binding Binding to a member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3). go-plus.json cullin binding http://purl.obolibrary.org/obo/GO_0097602 GO:0034089 biolink:BiologicalProcess establishment of meiotic sister chromatid cohesion The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0034089 GO:0097601 biolink:BiologicalProcess retina blood vessel maintenance A retina homeostatic process preventing the degeneration of a retina blood vessel. go-plus.json maintenance of retinal blood vessel|maintenance of retina blood vessel|maintenance of choriocapillaris http://purl.obolibrary.org/obo/GO_0097601 GO:0034088 biolink:BiologicalProcess maintenance of mitotic sister chromatid cohesion The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. go-plus.json mitotic cohesion stability http://purl.obolibrary.org/obo/GO_0034088 UBERON:0011092 biolink:AnatomicalEntity right pelvic girdle region A pelvic girdle region that is in the right side of a multicellular organism. go-plus.json right pelvic girdle http://purl.obolibrary.org/obo/UBERON_0011092 GO:0048684 biolink:BiologicalProcess positive regulation of collateral sprouting of intact axon in response to injury Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon. go-plus.json up regulation of collateral sprouting of intact axon in response to injury|activation of collateral sprouting of intact axon in response to injury|stimulation of collateral sprouting of intact axon in response to injury|up-regulation of collateral sprouting of intact axon in response to injury|upregulation of collateral sprouting of intact axon in response to injury http://purl.obolibrary.org/obo/GO_0048684 UBERON:0011091 biolink:AnatomicalEntity skeleton of left pelvic girdle A skeleton of pelvic girdle that is part of a left pelvic girdle region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011091 GO:0048683 biolink:BiologicalProcess regulation of collateral sprouting of intact axon in response to injury Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon. go-plus.json http://purl.obolibrary.org/obo/GO_0048683 GO:0048682 biolink:BiologicalProcess sprouting of injured axon The process involved in sprouting of an injured axon. go-plus.json http://purl.obolibrary.org/obo/GO_0048682 UBERON:0011090 biolink:AnatomicalEntity skeleton of right pelvic girdle A skeleton of pelvic girdle that is part of a right pelvic girdle region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011090 GO:0048681 biolink:BiologicalProcess negative regulation of axon regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration. go-plus.json down regulation of axon regeneration|downregulation of axon regeneration|down-regulation of axon regeneration|inhibition of axon regeneration http://purl.obolibrary.org/obo/GO_0048681 UBERON:0011096 biolink:AnatomicalEntity lacrimal nerve The lacrimal nerve is the smallest of the three branches of the ophthalmic division of the trigeminal nerve. go-plus.json nervus lacrimalis http://purl.obolibrary.org/obo/UBERON_0011096 GO:1903849 biolink:BiologicalProcess positive regulation of aorta morphogenesis Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. go-plus.json up regulation of aorta morphogenesis|activation of aorta morphogenesis|up-regulation of aorta morphogenesis|upregulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1903849 GO:0048680 biolink:BiologicalProcess positive regulation of axon regeneration Any process that activates, maintains or increases the rate of axon regeneration. go-plus.json upregulation of axon regeneration|up regulation of axon regeneration|activation of axon regeneration|stimulation of axon regeneration|up-regulation of axon regeneration http://purl.obolibrary.org/obo/GO_0048680 UBERON:0011095 biolink:AnatomicalEntity vertebra pre-cartilage condensation The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. go-plus.json vertebral pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0011095 GO:1903848 biolink:BiologicalProcess negative regulation of aorta morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. go-plus.json down-regulation of aorta morphogenesis|inhibition of aorta morphogenesis|down regulation of aorta morphogenesis|downregulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1903848 UBERON:0011094 biolink:AnatomicalEntity vertebra cartilage element The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. go-plus.json vertebral cartilage condensation http://purl.obolibrary.org/obo/UBERON_0011094 UBERON:0035021 biolink:AnatomicalEntity right vagus X nerve trunk go-plus.json trunk of right vagus|posterior vagus X nerve trunk|right vagus neural trunk http://purl.obolibrary.org/obo/UBERON_0035021 GO:1903847 biolink:BiologicalProcess regulation of aorta morphogenesis Any process that modulates the frequency, rate or extent of aorta morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1903847 GO:1903846 biolink:BiologicalProcess positive regulation of cellular response to transforming growth factor beta stimulus Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus. go-plus.json up regulation of cellular response to TGFbeta stimulus|activation of cellular response to TGFbeta stimulus|positive regulation of cellular response to TGFbeta stimulus|up-regulation of cellular response to TGF-beta stimulus|activation of cellular response to TGF-beta stimulus|upregulation of cellular response to transforming growth factor beta stimulus|positive regulation of cellular response to TGF-beta stimulus|up-regulation of cellular response to TGFbeta stimulus|up regulation of cellular response to transforming growth factor beta stimulus|up regulation of cellular response to TGF-beta stimulus|activation of cellular response to transforming growth factor beta stimulus|upregulation of cellular response to TGFbeta stimulus|upregulation of cellular response to TGF-beta stimulus|up-regulation of cellular response to transforming growth factor beta stimulus http://purl.obolibrary.org/obo/GO_1903846 UBERON:0035020 biolink:AnatomicalEntity left vagus X nerve trunk go-plus.json left vagus neural trunk|anterior vagus X nerve trunk|trunk of left vagus http://purl.obolibrary.org/obo/UBERON_0035020 UBERON:0011093 biolink:AnatomicalEntity left pelvic girdle region A pelvic girdle region that is in the left side of a multicellular organism. go-plus.json left pelvic girdle http://purl.obolibrary.org/obo/UBERON_0011093 GO:1903845 biolink:BiologicalProcess negative regulation of cellular response to transforming growth factor beta stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus. go-plus.json negative regulation of cellular response to TGFbeta stimulus|down-regulation of cellular response to TGFbeta stimulus|down regulation of cellular response to transforming growth factor beta stimulus|down-regulation of cellular response to TGF-beta stimulus|negative regulation of cellular response to TGF-beta stimulus|downregulation of cellular response to transforming growth factor beta stimulus|inhibition of cellular response to TGFbeta stimulus|downregulation of cellular response to TGF-beta stimulus|down-regulation of cellular response to transforming growth factor beta stimulus|down regulation of cellular response to TGF-beta stimulus|inhibition of cellular response to TGF-beta stimulus|down regulation of cellular response to TGFbeta stimulus|inhibition of cellular response to transforming growth factor beta stimulus|downregulation of cellular response to TGFbeta stimulus http://purl.obolibrary.org/obo/GO_1903845 GO:1903844 biolink:BiologicalProcess regulation of cellular response to transforming growth factor beta stimulus Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus. go-plus.json regulation of cellular response to TGF-beta stimulus|regulation of cellular response to TGFbeta stimulus http://purl.obolibrary.org/obo/GO_1903844 GO:1903843 biolink:BiologicalProcess cellular response to arsenite ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903843 GO:1903842 biolink:BiologicalProcess response to arsenite ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903842 GO:0048689 biolink:BiologicalProcess formation of growth cone in injured axon The formation of a growth cone in an injured axon. go-plus.json http://purl.obolibrary.org/obo/GO_0048689 GO:0048688 biolink:BiologicalProcess negative regulation of sprouting of injured axon Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon. go-plus.json down-regulation of sprouting of injured axon|inhibition of sprouting of injured axon|down regulation of sprouting of injured axon|downregulation of sprouting of injured axon http://purl.obolibrary.org/obo/GO_0048688 GO:1903841 biolink:BiologicalProcess cellular response to arsenite(3-) Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903841 GO:0048687 biolink:BiologicalProcess positive regulation of sprouting of injured axon Any process that activates, maintains or increases the rate of sprouting of an injured axon. go-plus.json activation of sprouting of injured axon|stimulation of sprouting of injured axon|up-regulation of sprouting of injured axon|upregulation of sprouting of injured axon|up regulation of sprouting of injured axon http://purl.obolibrary.org/obo/GO_0048687 GO:1903840 biolink:BiologicalProcess response to arsenite(3-) Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903840 GO:0048686 biolink:BiologicalProcess regulation of sprouting of injured axon Any process that modulates the frequency, rate or extent of sprouting of an injured axon. go-plus.json http://purl.obolibrary.org/obo/GO_0048686 GO:0048685 biolink:BiologicalProcess negative regulation of collateral sprouting of intact axon in response to injury Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon. go-plus.json down-regulation of collateral sprouting of intact axon in response to injury|inhibition of collateral sprouting of intact axon in response to injury|down regulation of collateral sprouting of intact axon in response to injury|downregulation of collateral sprouting of intact axon in response to injury http://purl.obolibrary.org/obo/GO_0048685 GO:0034076 biolink:MolecularActivity cucurbitadienol synthase activity Catalysis of the reaction: oxidosqualene = cucurbitadienol. go-plus.json http://purl.obolibrary.org/obo/GO_0034076 GO:0034075 biolink:MolecularActivity arabidiol synthase activity Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol). EC:4.2.1.124|MetaCyc:RXN-9684|RHEA:31035 go-plus.json http://purl.obolibrary.org/obo/GO_0034075 GO:0034074 biolink:MolecularActivity marneral synthase activity Catalysis of the reaction: oxidosqualene = marneral. MetaCyc:RXN-9664|RHEA:31875 go-plus.json http://purl.obolibrary.org/obo/GO_0034074 GO:0034073 biolink:MolecularActivity tetrahymanol cyclase activity Catalysis of the reaction: squalene = tetrahymanol. go-plus.json http://purl.obolibrary.org/obo/GO_0034073 GO:0034072 biolink:MolecularActivity squalene cyclase activity Catalysis of the reaction: squalene = triterpene. go-plus.json http://purl.obolibrary.org/obo/GO_0034072 GO:0034071 biolink:MolecularActivity aminoglycoside phosphotransferase activity Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside. EC:2.7.1.- go-plus.json aminoglycoside kinase activity http://purl.obolibrary.org/obo/GO_0034071 GO:0034070 biolink:MolecularActivity aminoglycoside 1-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring. go-plus.json http://purl.obolibrary.org/obo/GO_0034070 GO:0034079 biolink:BiologicalProcess butanediol biosynthetic process The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3. MetaCyc:P125-PWY go-plus.json butylene glycol biosynthesis|butylene glycol biosynthetic process|butanediol biosynthesis|butanediol anabolism|butanediol synthesis|butanediol formation http://purl.obolibrary.org/obo/GO_0034079 GO:0034078 biolink:BiologicalProcess butanediol catabolic process The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3. go-plus.json butylene glycol catabolic process|butanediol degradation|butanediol breakdown|butanediol utilization|butanediol catabolism|butylene glycol catabolism http://purl.obolibrary.org/obo/GO_0034078 GO:0034077 biolink:BiologicalProcess butanediol metabolic process The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3. go-plus.json butylene glycol metabolic process|butylene glycol metabolism|butanediol metabolism http://purl.obolibrary.org/obo/GO_0034077 GO:0048695 biolink:BiologicalProcess negative regulation of collateral sprouting of injured axon Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon. go-plus.json downregulation of collateral sprouting of injured axon|down regulation of collateral sprouting of injured axon|inhibition of collateral sprouting of injured axon|down-regulation of collateral sprouting of injured axon http://purl.obolibrary.org/obo/GO_0048695 GO:0048694 biolink:BiologicalProcess positive regulation of collateral sprouting of injured axon Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon. go-plus.json up regulation of collateral sprouting of injured axon|upregulation of collateral sprouting of injured axon|stimulation of collateral sprouting of injured axon|up-regulation of collateral sprouting of injured axon|activation of collateral sprouting of injured axon http://purl.obolibrary.org/obo/GO_0048694 GO:0048693 biolink:BiologicalProcess regulation of collateral sprouting of injured axon Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon. go-plus.json http://purl.obolibrary.org/obo/GO_0048693 GO:0048692 biolink:BiologicalProcess negative regulation of axon extension involved in regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration. go-plus.json inhibition of axon extension involved in regeneration|down regulation of axon extension involved in regeneration|downregulation of axon extension involved in regeneration|down-regulation of axon extension involved in regeneration http://purl.obolibrary.org/obo/GO_0048692 UBERON:0011085 biolink:AnatomicalEntity palatoquadrate arch The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]. go-plus.json dorsal pharyngeal arch 1|palatoquadrate arch|upper pharyngeal jaw|dorsal visceral arch 1|upper pharyngeal jaw|dorsal visceral arch 1|dorsal mandibular arch|upper jaw http://purl.obolibrary.org/obo/UBERON_0011085 GO:0048691 biolink:BiologicalProcess positive regulation of axon extension involved in regeneration Any process that activates, maintains or increases the rate of axon extension involved in regeneration. go-plus.json up-regulation of axon extension involved in regeneration|upregulation of axon extension involved in regeneration|up regulation of axon extension involved in regeneration|activation of axon extension involved in regeneration|stimulation of axon extension involved in regeneration http://purl.obolibrary.org/obo/GO_0048691 GO:0048690 biolink:BiologicalProcess regulation of axon extension involved in regeneration Any process that modulates the frequency, rate or extent of axon extension involved in regeneration. go-plus.json http://purl.obolibrary.org/obo/GO_0048690 GO:1903859 biolink:BiologicalProcess regulation of dendrite extension Any process that modulates the frequency, rate or extent of dendrite extension. go-plus.json http://purl.obolibrary.org/obo/GO_1903859 GO:1903858 biolink:BiologicalProcess protein localization to old growing cell tip A process in which a protein is transported to, or maintained in, a location within an old growing cell tip. go-plus.json protein localisation to old growing cell tip|protein localisation in old growing cell tip|protein localization in old growing cell tip http://purl.obolibrary.org/obo/GO_1903858 GO:1903857 biolink:BiologicalProcess negative regulation of cytokinin dehydrogenase activity Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity. go-plus.json negative regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of cytokinin oxidase activity|inhibition of cytokinin dehydrogenase activity|inhibition of N6-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of cytokinin oxidase activity|negative regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of cytokinin dehydrogenase activity|negative regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of cytokinin oxidase activity|negative regulation of cytokinin oxidase activity|down regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of cytokinin dehydrogenase activity|downregulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of cytokinin oxidase activity|down regulation of cytokinin dehydrogenase activity http://purl.obolibrary.org/obo/GO_1903857 GO:1903856 biolink:BiologicalProcess regulation of cytokinin dehydrogenase activity Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity. go-plus.json regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|regulation of cytokinin oxidase activity http://purl.obolibrary.org/obo/GO_1903856 UBERON:0035034 biolink:AnatomicalEntity eyelid epithelium An epithelium that is part of an eyelid [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035034 GO:1903855 biolink:BiologicalProcess positive regulation of stress response to copper ion Any process that activates or increases the frequency, rate or extent of stress response to copper ion. go-plus.json up-regulation of response to copper ion stress|upregulation of stress response to copper ion|upregulation of response to copper toxicity|upregulation of response to copper ion stress|up regulation of stress response to copper ion|up regulation of response to copper toxicity|positive regulation of response to copper toxicity|activation of stress response to copper ion|up regulation of response to copper ion stress|activation of response to copper toxicity|positive regulation of response to copper ion stress|activation of response to copper ion stress|up-regulation of stress response to copper ion|up-regulation of response to copper toxicity http://purl.obolibrary.org/obo/GO_1903855 UBERON:0011088 biolink:AnatomicalEntity ligament of knee joint A ligament that is part of a knee joint. go-plus.json knee joint ligament http://purl.obolibrary.org/obo/UBERON_0011088 CHEBI:87593 biolink:ChemicalSubstance 15alpha-hydroxyestradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87593 chebi_ph7_3 GO:1903854 biolink:BiologicalProcess negative regulation of stress response to copper ion Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion. go-plus.json inhibition of response to copper ion stress|down regulation of response to copper toxicity|down regulation of stress response to copper ion|downregulation of stress response to copper ion|downregulation of response to copper toxicity|down regulation of response to copper ion stress|downregulation of response to copper ion stress|down-regulation of response to copper toxicity|down-regulation of stress response to copper ion|negative regulation of response to copper toxicity|down-regulation of response to copper ion stress|negative regulation of response to copper ion stress|inhibition of stress response to copper ion|inhibition of response to copper toxicity http://purl.obolibrary.org/obo/GO_1903854 UBERON:0035036 biolink:AnatomicalEntity naris epithelium An epithelium that is part of a naris [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035036 GO:1903853 biolink:BiologicalProcess regulation of stress response to copper ion Any process that modulates the frequency, rate or extent of stress response to copper ion. go-plus.json regulation of response to copper toxicity|regulation of response to copper ion stress|regulation of stress response to copper http://purl.obolibrary.org/obo/GO_1903853 GO:0048699 biolink:BiologicalProcess generation of neurons The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. go-plus.json neuron generation http://purl.obolibrary.org/obo/GO_0048699 CHEBI:87598 biolink:ChemicalSubstance 7alpha-hydroxyestradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87598 chebi_ph7_3 GO:1903852 biolink:BiologicalProcess positive regulation of cristae formation Any process that activates or increases the frequency, rate or extent of cristae formation. go-plus.json upregulation of cristae formation|up regulation of cristae formation|activation of cristae formation|up-regulation of cristae formation http://purl.obolibrary.org/obo/GO_1903852 UBERON:0035037 biolink:AnatomicalEntity jaw epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0035037 GO:0048698 biolink:BiologicalProcess negative regulation of collateral sprouting in absence of injury Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury. go-plus.json down-regulation of collateral sprouting in the absence of injury|inhibition of collateral sprouting in the absence of injury|down regulation of collateral sprouting in the absence of injury|downregulation of collateral sprouting in the absence of injury http://purl.obolibrary.org/obo/GO_0048698 GO:1903851 biolink:BiologicalProcess negative regulation of cristae formation Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation. go-plus.json down regulation of cristae formation|downregulation of cristae formation|down-regulation of cristae formation|inhibition of cristae formation http://purl.obolibrary.org/obo/GO_1903851 GO:0048697 biolink:BiologicalProcess positive regulation of collateral sprouting in absence of injury Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury. go-plus.json up regulation of collateral sprouting in the absence of injury|activation of collateral sprouting in the absence of injury|stimulation of collateral sprouting in the absence of injury|up-regulation of collateral sprouting in the absence of injury|upregulation of collateral sprouting in the absence of injury http://purl.obolibrary.org/obo/GO_0048697 GO:1903850 biolink:BiologicalProcess regulation of cristae formation Any process that modulates the frequency, rate or extent of cristae formation. go-plus.json http://purl.obolibrary.org/obo/GO_1903850 GO:0048696 biolink:BiologicalProcess regulation of collateral sprouting in absence of injury Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury. go-plus.json http://purl.obolibrary.org/obo/GO_0048696 UBERON:0035039 biolink:AnatomicalEntity rectal artery go-plus.json hemorrhoidal artery http://purl.obolibrary.org/obo/UBERON_0035039 CL:1001599 biolink:Cell pancreas exocrine glandular cell Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. go-plus.json pancreas exocrine glandular cells|exocrine pancreas glandular cell http://purl.obolibrary.org/obo/CL_1001599 GO:0034065 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0034065 GO:0034064 biolink:CellularComponent Tor2-Mei2-Ste11 complex A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast. go-plus.json http://purl.obolibrary.org/obo/GO_0034064 CL:1001598 biolink:Cell small intestine glandular cell A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . go-plus.json small intestine glandular cells|small bowel glandular cell|small intestinal glandular cell http://purl.obolibrary.org/obo/CL_1001598 CL:1001597 biolink:Cell seminal vesicle glandular cell Glandular cell of seminal vesicle epithelium. go-plus.json seminal vesicle glandular cells http://purl.obolibrary.org/obo/CL_1001597 GO:0034063 biolink:BiologicalProcess stress granule assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. go-plus.json SG assembly http://purl.obolibrary.org/obo/GO_0034063 GO:0034062 biolink:MolecularActivity 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end. Reactome:R-HSA-6786881|Reactome:R-HSA-5696807 go-plus.json transcriptase|ribonucleic polymerase activity|RNA nucleotidyltransferase activity|ribonucleate nucleotidyltransferase activity|RNA transcriptase activity|ribonucleate polymerase activity|ribonucleic acid nucleotidyltransferase|ribonucleic transcriptase activity|RNA polymerase activity|C ribonucleic acid formation factors|ribonucleic acid transcriptase activity|C RNA formation factors|ribonucleic acid polymerase activity http://purl.obolibrary.org/obo/GO_0034062 CL:1001596 biolink:Cell salivary gland glandular cell Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts. go-plus.json salivary gland glandular cells http://purl.obolibrary.org/obo/CL_1001596 GO:0034061 biolink:MolecularActivity DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group. go-plus.json deoxynucleate polymerase activity|deoxyribonucleic acid polymerase activity|deoxyribonucleic polymerase activity|DNA nucleotidyltransferase activity|deoxyribonucleate nucleotidyltransferase activity http://purl.obolibrary.org/obo/GO_0034061 GO:0034060 biolink:CellularComponent cyanelle stroma The space enclosed by the double membrane of a cyanelle. go-plus.json http://purl.obolibrary.org/obo/GO_0034060 CL:1001593 biolink:Cell parathyroid glandular cell Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells. go-plus.json parathyroid gland glandular cells|parathyroid gland glandular cell http://purl.obolibrary.org/obo/CL_1001593 CL:1001592 biolink:Cell gall bladder glandular cell Glandular cell of gall bladder epithelium. go-plus.json gallbladder glandular cell|gallbladder glandular cells|gall bladder glandular cells http://purl.obolibrary.org/obo/CL_1001592 CL:1001591 biolink:Cell oviduct glandular cell Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells. go-plus.json fallopian tube glandular cell|uterine tube glandular cell|fallopian tube glandular cells http://purl.obolibrary.org/obo/CL_1001591 CL:1001590 biolink:Cell epididymis glandular cell Glandular cell of epididymal epithelium. go-plus.json epididymis glandular cells|epididymal glandular cell http://purl.obolibrary.org/obo/CL_1001590 PR:000011374 biolink:Protein atrial natriuretic factor A protein that is a translation product of the human NPPA gene or a 1:1 ortholog thereof. go-plus.json NPPA|CDD-ANF|atrial natriuretic peptide|ANP|PND|prepronatriodilatin|ANF http://purl.obolibrary.org/obo/PR_000011374 PO:0025545 biolink:OntologyClass anther wall tapetum cell A microsporangium tapetum cell (PO:0025544) that is part of the anther wall tapetum (PO:0009071). go-plus.json célula de la pared del tapete de la antera (Spanish, exact)|葯壁絨毯細胞 (Japanese, exact)|anther wall tapetal cell (exact) http://purl.obolibrary.org/obo/PO_0025545 GO:0034069 biolink:MolecularActivity aminoglycoside N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside. go-plus.json kanamycin acetyltransferase activity http://purl.obolibrary.org/obo/GO_0034069 GO:0034068 biolink:MolecularActivity aminoglycoside nucleotidyltransferase activity Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside. go-plus.json streptomycin adenylylase activity|streptomycin adenyltransferase activity|streptomycin adenylate synthetase activity|aminoglycoside adenylyltransferase activity|streptomycin-spectinomycin adenylyltransferase activity|streptomycin adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0034068 PO:0025544 biolink:OntologyClass microsporangium tapetum cell A tapetum cell (PO:0025543) that is part of a microsporangium tapetum (PO:0025314). go-plus.json célula del tapete del microsporangio (Spanish, exact)|小胞子嚢タペート細胞 (Japanese, exact)|microsporangium tapetal cell (exact) http://purl.obolibrary.org/obo/PO_0025544 GO:0034067 biolink:BiologicalProcess protein localization to Golgi apparatus A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. go-plus.json establishment of protein localization in Golgi|protein localization in Golgi apparatus|establishment of protein localization to Golgi apparatus|establishment of protein localization to Golgi|protein localisation in Golgi apparatus|protein-Golgi targeting|protein targeting to Golgi|establishment of protein localisation to Golgi http://purl.obolibrary.org/obo/GO_0034067 PO:0025543 biolink:OntologyClass tapetum cell A native plant cell (PO:0025606) that is part of the tapetum (PO:0025313). go-plus.json tapetal cell (exact)|célula del tapete (Spanish, exact)|タペート細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025543 GO:0034066 biolink:CellularComponent Ric1-Rgp1 guanyl-nucleotide exchange factor complex A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi. go-plus.json Ric1p-Rgp1p complex http://purl.obolibrary.org/obo/GO_0034066 NCBITaxon:2058949 biolink:OrganismalEntity Dictyosteliales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2058949 GO:0102870 biolink:MolecularActivity 7-hydroxyflavone-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+. MetaCyc:RXN-8355 go-plus.json http://purl.obolibrary.org/obo/GO_0102870 GO:0102872 biolink:MolecularActivity 1-16:0-2-18:2-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. EC:1.14.19.25|MetaCyc:RXN-8361 go-plus.json http://purl.obolibrary.org/obo/GO_0102872 GO:0102871 biolink:MolecularActivity 1-16:0-2-18:1-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-16:0-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-palmitoyl-2-linoleoyl-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. EC:1.14.19.22|MetaCyc:RXN-8360 go-plus.json http://purl.obolibrary.org/obo/GO_0102871 GO:0102874 biolink:MolecularActivity 1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8365 go-plus.json http://purl.obolibrary.org/obo/GO_0102874 GO:0102873 biolink:MolecularActivity 1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-8363 go-plus.json http://purl.obolibrary.org/obo/GO_0102873 GO:0102876 biolink:MolecularActivity psoralen synthase activity Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O. RHEA:19281|EC:1.14.14.141|MetaCyc:RXN-8386 go-plus.json http://purl.obolibrary.org/obo/GO_0102876 GO:0102875 biolink:MolecularActivity 1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8366 go-plus.json http://purl.obolibrary.org/obo/GO_0102875 CHEBI:18918 biolink:ChemicalSubstance 1,3-dichloropropene go-plus.json http://purl.obolibrary.org/obo/CHEBI_18918 GO:0102878 biolink:MolecularActivity (+)-alpha-barbatene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid. MetaCyc:RXN-8417|EC:4.2.3.69|RHEA:29499 go-plus.json http://purl.obolibrary.org/obo/GO_0102878 CHEBI:18917 biolink:ChemicalSubstance 1,3-dichloropropan-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18917 chebi_ph7_3 GO:0102877 biolink:MolecularActivity alpha-copaene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-copaene + diphosphoric acid. MetaCyc:RXN-8416|RHEA:33991|EC:4.2.3.133 go-plus.json http://purl.obolibrary.org/obo/GO_0102877 GO:0102879 biolink:MolecularActivity (+)-thujopsene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid. MetaCyc:RXN-8418|EC:4.2.3.79|RHEA:30375 go-plus.json http://purl.obolibrary.org/obo/GO_0102879 CHEBI:18913 biolink:ChemicalSubstance (1->3)-alpha-D-mannooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_18913 GO:0102881 biolink:MolecularActivity (+)-beta-barbatene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-barbatene + diphosphoric acid. MetaCyc:RXN-8421 go-plus.json http://purl.obolibrary.org/obo/GO_0102881 GO:0102880 biolink:MolecularActivity isobazzanene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> isobazzanene + diphosphoric acid. MetaCyc:RXN-8419 go-plus.json http://purl.obolibrary.org/obo/GO_0102880 GO:0102883 biolink:MolecularActivity (+)-beta-chamigrene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-chamigrene + diphosphoric acid. EC:4.2.3.78|MetaCyc:RXN-8424|RHEA:30379 go-plus.json http://purl.obolibrary.org/obo/GO_0102883 GO:0102882 biolink:MolecularActivity beta-acoradiene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid. MetaCyc:RXN-8423 go-plus.json http://purl.obolibrary.org/obo/GO_0102882 GO:0102885 biolink:MolecularActivity alpha-cuprenene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid. RHEA:32027|EC:4.2.3.95|MetaCyc:RXN-8426 go-plus.json http://purl.obolibrary.org/obo/GO_0102885 GO:0102884 biolink:MolecularActivity alpha-zingiberene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> zingiberene + diphosphoric acid. EC:4.2.3.65|RHEA:28643|MetaCyc:RXN-8425 go-plus.json http://purl.obolibrary.org/obo/GO_0102884 GO:0102887 biolink:MolecularActivity beta-sesquiphellandrene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphoric acid. MetaCyc:RXN-8430|RHEA:32699|EC:4.2.3.123 go-plus.json http://purl.obolibrary.org/obo/GO_0102887 GO:0102886 biolink:MolecularActivity alpha-chamigrene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-chamigrene + diphosphoric acid. MetaCyc:RXN-8428 go-plus.json http://purl.obolibrary.org/obo/GO_0102886 GO:0102889 biolink:MolecularActivity beta-elemene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-elemene + diphosphoric acid. MetaCyc:RXN-8432 go-plus.json http://purl.obolibrary.org/obo/GO_0102889 GO:0102888 biolink:MolecularActivity delta-cuprenene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid. MetaCyc:RXN-8431 go-plus.json http://purl.obolibrary.org/obo/GO_0102888 CHEBI:18904 biolink:ChemicalSubstance (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_18904 chebi_ph7_3 GO:0102890 biolink:MolecularActivity naringenin chalcone 4'-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone <=> UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+. MetaCyc:RXN-8453|RHEA:34291|EC:2.4.1.286 go-plus.json http://purl.obolibrary.org/obo/GO_0102890 GO:0102892 biolink:MolecularActivity betanidin 5-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + betanin + UDP. MetaCyc:RXN-8479 go-plus.json http://purl.obolibrary.org/obo/GO_0102892 GO:0102891 biolink:MolecularActivity 2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP. MetaCyc:RXN-8455|RHEA:34295|EC:2.4.1.286 go-plus.json http://purl.obolibrary.org/obo/GO_0102891 GO:0102894 biolink:MolecularActivity UDPG:cyclo-DOPA 5-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP. MetaCyc:RXN-8481 go-plus.json http://purl.obolibrary.org/obo/GO_0102894 GO:0102893 biolink:MolecularActivity betanidin 6-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + gomphrenin I + UDP. MetaCyc:RXN-8480 go-plus.json http://purl.obolibrary.org/obo/GO_0102893 GO:0102896 biolink:MolecularActivity colnelenate synthase activity Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O. MetaCyc:RXN-8498|RHEA:28178 go-plus.json http://purl.obolibrary.org/obo/GO_0102896 GO:0102895 biolink:MolecularActivity colneleate synthase activity Catalysis of the reaction: 9(S)-HPODE <=> colneleate + H2O. MetaCyc:RXN-8496|EC:4.2.1.121|RHEA:28174 go-plus.json http://purl.obolibrary.org/obo/GO_0102895 GO:0102898 biolink:MolecularActivity levopimaradienol hydroxylase activity Catalysis of the reaction: H+ + levopimaradienol + NADPH + O2 <=> levopiramadiene-diol + NADP + H2O. MetaCyc:RXN-8517 go-plus.json http://purl.obolibrary.org/obo/GO_0102898 GO:0102897 biolink:MolecularActivity abietadienal hydroxylase activity Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O. RHEA:56928|MetaCyc:RXN-8510 go-plus.json http://purl.obolibrary.org/obo/GO_0102897 GO:0102899 biolink:MolecularActivity dehydroabietadienol hydroxylase activity Catalysis of the reaction: H+ + dehydroabietadienol + NADPH + O2 <=> dehydroabietadiene-diol + NADP + H2O. MetaCyc:RXN-8532 go-plus.json http://purl.obolibrary.org/obo/GO_0102899 GO:0102830 biolink:MolecularActivity verbascose synthase activity Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose. MetaCyc:RXN-8286 go-plus.json http://purl.obolibrary.org/obo/GO_0102830 GO:0102832 biolink:MolecularActivity verbascose galactinol:ajugose galactosyltransferase activity Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol. MetaCyc:RXN-8288 go-plus.json http://purl.obolibrary.org/obo/GO_0102832 GO:0102831 biolink:MolecularActivity stachyose synthase activity Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose. MetaCyc:RXN-8287 go-plus.json http://purl.obolibrary.org/obo/GO_0102831 GO:0102834 biolink:MolecularActivity 1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-8294 go-plus.json http://purl.obolibrary.org/obo/GO_0102834 GO:0102833 biolink:MolecularActivity sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> D-galactosylononitol + myo-inositol. MetaCyc:RXN-8292 go-plus.json http://purl.obolibrary.org/obo/GO_0102833 GO:0102836 biolink:MolecularActivity 1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-8296 go-plus.json http://purl.obolibrary.org/obo/GO_0102836 GO:0102835 biolink:MolecularActivity 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8295 go-plus.json http://purl.obolibrary.org/obo/GO_0102835 GO:0102838 biolink:MolecularActivity 1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-8298 go-plus.json http://purl.obolibrary.org/obo/GO_0102838 GO:0102837 biolink:MolecularActivity 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8297 go-plus.json http://purl.obolibrary.org/obo/GO_0102837 GO:0102839 biolink:MolecularActivity 1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8299 go-plus.json http://purl.obolibrary.org/obo/GO_0102839 GO:0102841 biolink:MolecularActivity 1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-8302 go-plus.json http://purl.obolibrary.org/obo/GO_0102841 GO:0102840 biolink:MolecularActivity 1-18:2-2-16:3-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-16:3-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8301|EC:1.14.19.35 go-plus.json http://purl.obolibrary.org/obo/GO_0102840 GO:0102843 biolink:MolecularActivity 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming) Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8304|EC:1.14.19.42|RHEA:46756 go-plus.json http://purl.obolibrary.org/obo/GO_0102843 GO:0102842 biolink:MolecularActivity 1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming) Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8303|RHEA:46412|EC:1.14.19.35 go-plus.json http://purl.obolibrary.org/obo/GO_0102842 GO:0102845 biolink:MolecularActivity 1-18:3-2-16:0-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:3-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8307 go-plus.json http://purl.obolibrary.org/obo/GO_0102845 GO:0102844 biolink:MolecularActivity 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming) Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-8305 go-plus.json http://purl.obolibrary.org/obo/GO_0102844 GO:0102847 biolink:MolecularActivity 1-18:3-2-16:2-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8309 go-plus.json http://purl.obolibrary.org/obo/GO_0102847 GO:0102846 biolink:MolecularActivity 1-18:3-2-16:1-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8308 go-plus.json http://purl.obolibrary.org/obo/GO_0102846 GO:0102849 biolink:MolecularActivity 1-18:2-2-18:3-digalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8314 go-plus.json http://purl.obolibrary.org/obo/GO_0102849 GO:0102848 biolink:MolecularActivity 1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.35|MetaCyc:RXN-8310 go-plus.json http://purl.obolibrary.org/obo/GO_0102848 CHEBI:147369 biolink:ChemicalSubstance glucotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_147369 GO:0004385 biolink:MolecularActivity guanylate kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP. EC:2.7.4.8|Reactome:R-HSA-110133|RHEA:20780|MetaCyc:GUANYL-KIN-RXN|Reactome:R-HSA-73788 go-plus.json ATP:GMP phosphotransferase activity|guanosine monophosphate kinase activity|membrane-associated guanylate kinase|deoxyguanylate kinase activity|ATP:(d)GMP phosphotransferase activity|5'-GMP kinase activity|GMP kinase activity http://purl.obolibrary.org/obo/GO_0004385 GO:0102850 biolink:MolecularActivity 1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8316|EC:1.14.19.23|RHEA:46376 go-plus.json http://purl.obolibrary.org/obo/GO_0102850 GO:0004384 biolink:MolecularActivity obsolete membrane-associated guanylate kinase OBSOLETE. Catalysis of the reaction: ATP + GMP = ADP + GDP, associated with the cell membrane. go-plus.json MAGUK|membrane-associated guanylate kinase http://purl.obolibrary.org/obo/GO_0004384 GO:0102852 biolink:MolecularActivity 1-18:3-2-16:0-phosphatidylglycerol desaturase activity Catalysis of the reaction: 1-18:3-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8319 go-plus.json http://purl.obolibrary.org/obo/GO_0102852 GO:0004386 biolink:MolecularActivity helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. Reactome:R-HSA-5686410|Reactome:R-HSA-169468|Reactome:R-HSA-169461|Reactome:R-HSA-5690996 go-plus.json ATP-dependent helicase activity http://purl.obolibrary.org/obo/GO_0004386 goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus|goslim_generic|goslim_chembl GO:0102851 biolink:MolecularActivity 1-18:2-2-16:0-phosphatidylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8318|EC:1.14.19.43 go-plus.json http://purl.obolibrary.org/obo/GO_0102851 GO:0004381 biolink:MolecularActivity fucosylgalactoside 3-alpha-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose. RHEA:14349|MetaCyc:2.4.1.37-RXN|Reactome:R-HSA-9033961|EC:2.4.1.37|Reactome:R-HSA-9034053 go-plus.json UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity|histo-blood substance beta-dependent galactosyltransferase activity|glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity|UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity|[blood group substance] alpha-galactosyltransferase activity|B transferase activity|UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|blood-group substance beta-dependent galactosyltransferase activity|histo-blood substance B-dependent galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|fucosylglycoprotein 3-alpha-galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|blood-group substance B-dependent galactosyltransferase activity|histo-blood group B transferase activity|UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0004381 GO:0102854 biolink:MolecularActivity 1-18:2-2-18:1-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8321 go-plus.json http://purl.obolibrary.org/obo/GO_0102854 GO:0004380 biolink:MolecularActivity glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose. EC:2.4.1.40|RHEA:19021|Reactome:R-HSA-9034042|Reactome:R-HSA-9033959|MetaCyc:2.4.1.40-RXN go-plus.json fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|A transferase activity|blood-group substance A-dependent acetylgalactosaminyltransferase activity|histo-blood group A acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|blood-group substance alpha-acetyltransferase activity|histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)|fucosylgalactose acetylgalactosaminyltransferase activity|alpha-3-N-acetylgalactosaminyltransferase activity|UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity|fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity|A-transferase activity|histo-blood group A transferase activity http://purl.obolibrary.org/obo/GO_0004380 GO:0102853 biolink:MolecularActivity 1-18:1-2-18:1-sn-glycerol-3-phosphocholine desaturase activity Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8320 go-plus.json http://purl.obolibrary.org/obo/GO_0102853 GO:0102856 biolink:MolecularActivity 1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. EC:1.14.19.25|MetaCyc:RXN-8323 go-plus.json http://purl.obolibrary.org/obo/GO_0102856 GO:0004383 biolink:MolecularActivity guanylate cyclase activity Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. RHEA:13665|MetaCyc:GUANYLCYC-RXN|EC:4.6.1.2|Reactome:R-HSA-74885|Reactome:R-HSA-392152 go-plus.json GTP diphosphate-lyase (cyclizing) activity|receptor guanylate cyclase activity|guanylyl cyclase activity|guanyl cyclase activity|GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity http://purl.obolibrary.org/obo/GO_0004383 GO:0102855 biolink:MolecularActivity 1-18:1-2-18:2-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor. EC:1.14.19.22|MetaCyc:RXN-8322|RHEA:46332 go-plus.json http://purl.obolibrary.org/obo/GO_0102855 GO:0004382 biolink:MolecularActivity guanosine-diphosphatase activity Catalysis of the reaction: GDP + H2O = GMP + phosphate. RHEA:22156|EC:3.6.1.42|MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN go-plus.json GDP phosphohydrolase activity|guanosine 5'-diphosphatase activity|guanosine diphosphatase activity|GDPase activity http://purl.obolibrary.org/obo/GO_0004382 GO:0102858 biolink:MolecularActivity 1-18:2-2-18:3-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-18:2-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8325 go-plus.json http://purl.obolibrary.org/obo/GO_0102858 GO:0102857 biolink:MolecularActivity 1-18:1-2-18:3-phosphatidylcholinedesaturase activity Catalysis of the reaction: 1-18:1-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. EC:1.14.19.22|MetaCyc:RXN-8324 go-plus.json http://purl.obolibrary.org/obo/GO_0102857 GO:0102859 biolink:MolecularActivity 1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming) Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. EC:1.14.19.25|MetaCyc:RXN-8326|RHEA:46404 go-plus.json http://purl.obolibrary.org/obo/GO_0102859 GO:0004399 biolink:MolecularActivity histidinol dehydrogenase activity Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+. MetaCyc:HISTOLDEHYD-RXN|EC:1.1.1.23|MetaCyc:HISTALDEHYD-RXN|RHEA:20641 go-plus.json http://purl.obolibrary.org/obo/GO_0004399 GO:0004396 biolink:MolecularActivity hexokinase activity Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate. RHEA:22740|EC:2.7.1.1|MetaCyc:HEXOKINASE-RXN go-plus.json ATP:D-hexose 6-phosphotransferase activity|hexokinase type III activity|hexokinase type I activity|glucose ATP phosphotransferase activity|hexokinase type IV|ATP-dependent hexokinase activity|hexokinase type IV glucokinase activity|hexokinase (phosphorylating)|hexokinase type IV (glucokinase) activity|hexokinase type II activity|hexokinase D http://purl.obolibrary.org/obo/GO_0004396 GO:0102861 biolink:MolecularActivity 1-18:2-2-18:1-phosphatidylcholine desaturase activity (SN2-18:2 forming) Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8328|EC:1.14.19.22 go-plus.json http://purl.obolibrary.org/obo/GO_0102861 GO:0004395 biolink:MolecularActivity hexaprenyldihydroxybenzoate methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate. MetaCyc:2.1.1.114-RXN|RHEA:14121|EC:2.1.1.114 go-plus.json S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity|DHHB methyltransferase activity|3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity|dihydroxyhexaprenylbenzoate methyltransferase activity|DHHB-Mt activity http://purl.obolibrary.org/obo/GO_0004395 GO:0102860 biolink:MolecularActivity 1-18:1-2-18:2-phosphatidylcholine synthase activity Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:1-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8327|EC:1.14.19.22 go-plus.json http://purl.obolibrary.org/obo/GO_0102860 GO:0102863 biolink:MolecularActivity 1-18:3-2-18:1-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8330 go-plus.json http://purl.obolibrary.org/obo/GO_0102863 GO:0004398 biolink:MolecularActivity histidine decarboxylase activity Catalysis of the reaction: L-histidine = histamine + CO2. Reactome:R-HSA-977301|EC:4.1.1.22|RHEA:20840|MetaCyc:HISTIDINE-DECARBOXYLASE-RXN go-plus.json L-histidine carboxy-lyase activity|L-histidine carboxy-lyase (histamine-forming)|L-histidine decarboxylase activity http://purl.obolibrary.org/obo/GO_0004398 GO:0102862 biolink:MolecularActivity 1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming) Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8329|EC:1.14.19.25 go-plus.json http://purl.obolibrary.org/obo/GO_0102862 GO:0004397 biolink:MolecularActivity histidine ammonia-lyase activity Catalysis of the reaction: L-histidine = urocanate + NH3. Reactome:R-HSA-70899|MetaCyc:HISTIDINE-AMMONIA-LYASE-RXN|RHEA:21232|EC:4.3.1.3 go-plus.json histidinase activity|L-histidine ammonia-lyase (urocanate-forming)|L-histidine ammonia-lyase activity|histidine alpha-deaminase activity|histidase activity http://purl.obolibrary.org/obo/GO_0004397 GO:0004392 biolink:MolecularActivity heme oxygenase (decyclizing) activity Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase]. Reactome:R-HSA-189398|RHEA:21764|MetaCyc:HEME-OXYGENASE-DECYCLIZING-RXN|EC:1.14.14.18 go-plus.json haem oxygenase (decyclizing) activity|heme oxidase activity|heme oxygenase activity|ORP33 proteins|haem oxidase activity|haem oxygenase activity|heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating) http://purl.obolibrary.org/obo/GO_0004392 GO:0102865 biolink:MolecularActivity delta6-acyl-lipid desaturase activity Catalysis of the reaction: a gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H(2)O. MetaCyc:RXN-8343|RHEA:46536|EC:1.14.19.38 go-plus.json http://purl.obolibrary.org/obo/GO_0102865 GO:0102864 biolink:MolecularActivity 1-18:3-2-18:2-phosphatidylcholine desaturase activity Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-8331 go-plus.json http://purl.obolibrary.org/obo/GO_0102864 GO:0102867 biolink:MolecularActivity molybdenum cofactor sulfurtransferase activity Catalysis of the reaction: 2 H+ + MoO2-molybdopterin cofactor(2-) + L-cysteine <=> thio-molybdenum cofactor + L-alanine + H2O. RHEA:42636|EC:2.8.1.9|MetaCyc:RXN-8351 go-plus.json http://purl.obolibrary.org/obo/GO_0102867 GO:0004394 biolink:MolecularActivity heparan sulfate 2-O-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate. Reactome:R-HSA-2076508|EC:2.8.2.- go-plus.json heparin-sulphate 2-sulphotransferase activity|heparan-sulfate 2-O-sulphotransferase activity|heparin 2-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0004394 GO:0004393 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004393 GO:0102866 biolink:MolecularActivity di-homo-gamma-linolenate delta5 desaturase activity Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor <=> arachidonate + 2 H2O + an oxidized electron acceptor. RHEA:46260|MetaCyc:RXN-8346 go-plus.json http://purl.obolibrary.org/obo/GO_0102866 GO:0102869 biolink:MolecularActivity 6-hydroxyflavone-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 6-hydroxyflavone <=> 6-O-beta-D-glucosyl-6-hydroxyflavone + UDP + H+. MetaCyc:RXN-8354 go-plus.json http://purl.obolibrary.org/obo/GO_0102869 GO:0102868 biolink:MolecularActivity 24-epi-campsterol desaturase activity Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O. MetaCyc:RXN-8352 go-plus.json http://purl.obolibrary.org/obo/GO_0102868 CHEBI:28325 biolink:ChemicalSubstance (S)-3-hydroxydecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28325 CHEBI:28328 biolink:ChemicalSubstance D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28328 GO:0043971 biolink:BiologicalProcess histone H3-K18 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone. go-plus.json histone H3K18 acetylation|histone H3 acetylation at K18 http://purl.obolibrary.org/obo/GO_0043971 GO:0043970 biolink:BiologicalProcess histone H3-K9 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone. go-plus.json histone H3 acetylation at K9|histone H3K9 acetylation http://purl.obolibrary.org/obo/GO_0043970 GO:0043973 biolink:BiologicalProcess histone H3-K4 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone. go-plus.json histone H3 acetylation at K4|histone H3K4 acetylation http://purl.obolibrary.org/obo/GO_0043973 CHEBI:28324 biolink:ChemicalSubstance 11-deoxycortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28324 chebi_ph7_3 CHEBI:28323 biolink:ChemicalSubstance 3,4-dihydroxycinnamaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_28323 chebi_ph7_3 GO:0043972 biolink:BiologicalProcess histone H3-K23 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone. go-plus.json histone H3K23 acetylation|histone H3 acetylation at K23 http://purl.obolibrary.org/obo/GO_0043972 CHEBI:228 biolink:ChemicalSubstance (4R,7R)-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_228 chebi_ph7_3 CHEBI:77292 biolink:ChemicalSubstance 1-(1Z)-hexadecenyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77292 chebi_ph7_3 GO:0043979 biolink:BiologicalProcess histone H2B-K5 acetylation The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone. go-plus.json histone H2B acetylation at K5 http://purl.obolibrary.org/obo/GO_0043979 GO:0043978 biolink:BiologicalProcess histone H2A-K9 acetylation The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone. go-plus.json histone H2A acetylation at K9 http://purl.obolibrary.org/obo/GO_0043978 CHEBI:77291 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77291 chebi_ph7_3 CHEBI:77290 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77290 chebi_ph7_3 CHEBI:77296 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77296 chebi_ph7_3 CHEBI:43967 biolink:ChemicalSubstance N(2),N(2)-dimethylguanosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_43967 GO:0043975 biolink:BiologicalProcess histone H3-K36 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone. go-plus.json histone H3K36 acetylation|histone H3 acetylation at K36 http://purl.obolibrary.org/obo/GO_0043975 CHEBI:227 biolink:ChemicalSubstance (-)-cis-carveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_227 chebi_ph7_3 GO:0043974 biolink:BiologicalProcess histone H3-K27 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone. go-plus.json histone H3K27 acetylation|histone H3 acetylation at K27 http://purl.obolibrary.org/obo/GO_0043974 CHEBI:43966 biolink:ChemicalSubstance melagatran go-plus.json http://purl.obolibrary.org/obo/CHEBI_43966 CHEBI:77295 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77295 chebi_ph7_3 GO:0043977 biolink:BiologicalProcess histone H2A-K5 acetylation The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone. go-plus.json histone H2A acetylation at K5 http://purl.obolibrary.org/obo/GO_0043977 CHEBI:77294 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77294 chebi_ph7_3 CHEBI:77293 biolink:ChemicalSubstance (E)-2,3-didehydropristanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77293 chebi_ph7_3 GO:0043976 biolink:BiologicalProcess histone H3-K79 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone. go-plus.json histone H3K79 acetylation|histone H3 acetylation at K79 http://purl.obolibrary.org/obo/GO_0043976 CHEBI:77297 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77297 chebi_ph7_3 CHEBI:28339 biolink:ChemicalSubstance lactose 6'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28339 GO:0043982 biolink:BiologicalProcess histone H4-K8 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone. go-plus.json histone H4 acetylation at K8 http://purl.obolibrary.org/obo/GO_0043982 GO:0043981 biolink:BiologicalProcess histone H4-K5 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone. go-plus.json histone H4 acetylation at K5 http://purl.obolibrary.org/obo/GO_0043981 GO:0043984 biolink:BiologicalProcess histone H4-K16 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone. go-plus.json histone H4 acetylation at K16 http://purl.obolibrary.org/obo/GO_0043984 GO:0043983 biolink:BiologicalProcess histone H4-K12 acetylation The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone. go-plus.json histone H4 acetylation at K12 http://purl.obolibrary.org/obo/GO_0043983 GO:0043980 biolink:BiologicalProcess histone H2B-K12 acetylation The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone. go-plus.json histone H2B acetylation at K12 http://purl.obolibrary.org/obo/GO_0043980 CHEBI:28331 biolink:ChemicalSubstance erythromycin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_28331 CHEBI:28330 biolink:ChemicalSubstance 4-hydroxy-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28330 GO:0043989 biolink:BiologicalProcess histone H4-S1 phosphorylation The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone. go-plus.json histone H4 phosphorylation at S1|histone H4S1 phosphorylation http://purl.obolibrary.org/obo/GO_0043989 CHEBI:233 biolink:ChemicalSubstance (4S,7R)-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_233 chebi_ph7_3 CHEBI:232 biolink:ChemicalSubstance (+)-cis-carveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_232 chebi_ph7_3 GO:0043986 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043986 GO:0043985 biolink:BiologicalProcess histone H4-R3 methylation The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone. go-plus.json histone H4 methylation at R3|histone H4R3me|histone H4 R3 methylation http://purl.obolibrary.org/obo/GO_0043985 GO:0043988 biolink:BiologicalProcess histone H3-S28 phosphorylation The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone. go-plus.json histone H3S28 phosphorylation|histone H3 phosphorylation at S28 http://purl.obolibrary.org/obo/GO_0043988 GO:0043987 biolink:BiologicalProcess histone H3-S10 phosphorylation The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone. go-plus.json histone H3S10 phosphorylation|histone H3 phosphorylation at S10 http://purl.obolibrary.org/obo/GO_0043987 CHEBI:28307 biolink:ChemicalSubstance precorrin-3A go-plus.json http://purl.obolibrary.org/obo/CHEBI_28307 CHEBI:28304 biolink:ChemicalSubstance heparin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28304 chebi_ph7_3 CHEBI:28303 biolink:ChemicalSubstance 2-chlorobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28303 chebi_ph7_3 GO:0043993 biolink:MolecularActivity histone acetyltransferase activity (H3-K18 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18). go-plus.json histone lysine N-acetyltransferase activity (H3-K18 specific) http://purl.obolibrary.org/obo/GO_0043993 CHEBI:28300 biolink:ChemicalSubstance glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28300 GO:0043992 biolink:MolecularActivity histone acetyltransferase activity (H3-K9 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9). go-plus.json histone lysine N-acetyltransferase activity (H3-K9 specific) http://purl.obolibrary.org/obo/GO_0043992 GO:0043995 biolink:MolecularActivity histone acetyltransferase activity (H4-K5 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5). go-plus.json histone lysine N-acetyltransferase activity (H4-K5 specific) http://purl.obolibrary.org/obo/GO_0043995 CHEBI:28302 biolink:ChemicalSubstance glucuronoarabinoxylan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28302 GO:0043994 biolink:MolecularActivity histone acetyltransferase activity (H3-K23 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23). go-plus.json histone lysine N-acetyltransferase activity (H3-K23 specific) http://purl.obolibrary.org/obo/GO_0043994 GO:0043991 biolink:BiologicalProcess histone H2B-S14 phosphorylation The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone. go-plus.json histone H2BS14 phosphorylation|histone H2B phosphorylation at S14 http://purl.obolibrary.org/obo/GO_0043991 GO:0043990 biolink:BiologicalProcess histone H2A-S1 phosphorylation The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone. go-plus.json histone H2A phosphorylation at S1|histone H2AS1 phosphorylation http://purl.obolibrary.org/obo/GO_0043990 GO:0043997 biolink:MolecularActivity histone acetyltransferase activity (H4-K12 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12). go-plus.json histone lysine N-acetyltransferase activity (H4-K12 specific) http://purl.obolibrary.org/obo/GO_0043997 GO:0043996 biolink:MolecularActivity histone acetyltransferase activity (H4-K8 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8). go-plus.json histone lysine N-acetyltransferase activity (H4-K8 specific) http://purl.obolibrary.org/obo/GO_0043996 GO:0043999 biolink:MolecularActivity histone acetyltransferase activity (H2A-K5 specific) Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5). go-plus.json histone lysine N-acetyltransferase activity (H2A-K5 specific) http://purl.obolibrary.org/obo/GO_0043999 CHEBI:412516 biolink:ChemicalSubstance 5-hydroxymethylfurfural go-plus.json http://purl.obolibrary.org/obo/CHEBI_412516 chebi_ph7_3 GO:0043998 biolink:MolecularActivity H2A histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine. go-plus.json H2A histone lysine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0043998 CHEBI:28319 biolink:ChemicalSubstance L-fucopyranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28319 CHEBI:28318 biolink:ChemicalSubstance 3,6-dichlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28318 PO:0025197 biolink:OntologyClass stele A cardinal organ part (PO:0025001) that is the central column of a plant axis that consists of the primary vascular tissue and associated ground tissue. go-plus.json estela (Spanish, exact)|中心柱, central cylinder (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025197 PO:0025195 biolink:OntologyClass pollen tube cell A native plant cell (PO:0025606) that develops from a microgametophyte vegetative cell (PO:0020099) and forms a tubular extension of the pollen (PO:0025281). go-plus.json 花粉管細胞 (Japanese, exact)|célula del tubo polínico (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025195 CHEBI:28317 biolink:ChemicalSubstance 3-aminobutyryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28317 CHEBI:28311 biolink:ChemicalSubstance indol-3-ylacetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_28311 chebi_ph7_3 CHEBI:28310 biolink:ChemicalSubstance 1D-3-O-methyl-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28310 chebi_ph7_3 UBERON:0006135 biolink:AnatomicalEntity myelinated nerve fiber Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH) go-plus.json http://purl.obolibrary.org/obo/UBERON_0006135 UBERON:0006134 biolink:AnatomicalEntity nerve fiber A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if it is myelinated) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system. go-plus.json nerve fibre|nerve fibers|neurofibra|neurofibra|neurofibrum http://purl.obolibrary.org/obo/UBERON_0006134 UBERON:0006133 biolink:AnatomicalEntity funiculus of neuraxis The cerebrospinal nerves consist of numerous nerve fibers collected together and enclosed in membranous sheaths. A small bundle of fibers, enclosed in a tubular sheath, is called a funiculus; if the nerve is of small size, it may consist only of a single funiculus; but if large, the funiculi are collected together into larger bundles or fasciculi, which are bound together in a common membranous investment. Examples include: Anterior funiculus of the spinal cord Lateral funiculus of the spinal cord Posterior funiculus of the spinal cord Funiculus solitarius of the medulla Funiculus separans go-plus.json http://purl.obolibrary.org/obo/UBERON_0006133 UBERON:0006136 biolink:AnatomicalEntity unmyelinated nerve fiber go-plus.json non-myelinated nerve fiber http://purl.obolibrary.org/obo/UBERON_0006136 UBERON:0006192 biolink:AnatomicalEntity mesonephric proximal tubule The mesonephric proximal tubule extends from the capsule to the distal tubule go-plus.json http://purl.obolibrary.org/obo/UBERON_0006192 UBERON:0006190 biolink:AnatomicalEntity mesonephric distal tubule The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule go-plus.json http://purl.obolibrary.org/obo/UBERON_0006190 CHEBI:18946 biolink:ChemicalSubstance delta-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_18946 UBERON:0006196 biolink:AnatomicalEntity mesonephric sinus A renal sinus that is part of a mesonephros. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006196 UBERON:0006195 biolink:AnatomicalEntity renal sinus of left kidney A renal sinus that is part of a left kidney. go-plus.json left renal sinus http://purl.obolibrary.org/obo/UBERON_0006195 UBERON:0006194 biolink:AnatomicalEntity renal sinus of right kidney A renal sinus that is part of a right kidney. go-plus.json right renal sinus http://purl.obolibrary.org/obo/UBERON_0006194 CHEBI:172368 biolink:ChemicalSubstance brominated flame retardant go-plus.json http://purl.obolibrary.org/obo/CHEBI_172368 UBERON:0006182 biolink:AnatomicalEntity mesonephric glomerular mesangium The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus go-plus.json http://purl.obolibrary.org/obo/UBERON_0006182 UBERON:0006189 biolink:AnatomicalEntity mesonephric connecting tubule The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros go-plus.json http://purl.obolibrary.org/obo/UBERON_0006189 UBERON:0006183 biolink:AnatomicalEntity mesonephric glomerular capillary . go-plus.json http://purl.obolibrary.org/obo/UBERON_0006183 UBERON:0006171 biolink:AnatomicalEntity renal sinus A hollowed out area on the medial margin of the kidney. The renal sinus opens at the renal hilum; it contains the renal aa. and vv., major calyces and renal pelvis, perirenal fat go-plus.json http://purl.obolibrary.org/obo/UBERON_0006171 UBERON:0006170 biolink:AnatomicalEntity mesonephric capsule The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006170 UBERON:0006175 biolink:AnatomicalEntity pronephric distal tubule go-plus.json http://purl.obolibrary.org/obo/UBERON_0006175 UBERON:0006174 biolink:AnatomicalEntity pronephric sinus The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules go-plus.json http://purl.obolibrary.org/obo/UBERON_0006174 UBERON:0006173 biolink:AnatomicalEntity pronephric proximal tubule go-plus.json pronephros proximal tubule http://purl.obolibrary.org/obo/UBERON_0006173 UBERON:0006172 biolink:AnatomicalEntity rectal diverticulum The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior go-plus.json rectal diverticula http://purl.obolibrary.org/obo/UBERON_0006172 CHEBI:77219 biolink:ChemicalSubstance (9Z,12Z)-hexadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77219 chebi_ph7_3 CHEBI:77218 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77218 chebi_ph7_3 CHEBI:77217 biolink:ChemicalSubstance (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77217 chebi_ph7_3 PO:0025262 biolink:OntologyClass plant ovary septum A septum (PO:0000030) that divides a multilocular plant ovary (PO:0009072). go-plus.json carpel synonym (related)|ovary dissepiment (broad)|子房隔壁 (Japanese, exact)|septo del ovario (Spanish, exact)|ovary septa (exact, plural) http://purl.obolibrary.org/obo/PO_0025262 GO:0018928 biolink:BiologicalProcess methyl ethyl ketone metabolic process The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints. UM-BBD_pathwayID:mek go-plus.json methyl ethyl ketone metabolism|MEK metabolic process|2-butanone metabolic process|MEK metabolism|2-butanone metabolism http://purl.obolibrary.org/obo/GO_0018928 GO:0018927 biolink:BiologicalProcess obsolete methionine and threonine metabolic process OBSOLETE. (Was not defined before being made obsolete). go-plus.json methionine and threonine metabolic process http://purl.obolibrary.org/obo/GO_0018927 GO:0018929 biolink:BiologicalProcess methyl fluoride metabolic process The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils. UM-BBD_pathwayID:mf go-plus.json methyl fluoride metabolism http://purl.obolibrary.org/obo/GO_0018929 CHEBI:28286 biolink:ChemicalSubstance cyclohexane-1,4-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_28286 chebi_ph7_3 GO:0018924 biolink:BiologicalProcess mandelate metabolic process The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic. UM-BBD_pathwayID:mca go-plus.json mandelate metabolism|mandelic acid metabolism|mandelic acid metabolic process http://purl.obolibrary.org/obo/GO_0018924 GO:0018923 biolink:BiologicalProcess limonene metabolic process The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. UM-BBD_pathwayID:lim go-plus.json limonene metabolism http://purl.obolibrary.org/obo/GO_0018923 CHEBI:28291 biolink:ChemicalSubstance 3-hydroxyisovaleryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28291 GO:0018926 biolink:BiologicalProcess methanesulfonic acid metabolic process The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide. UM-BBD_pathwayID:msa go-plus.json methanesulphonic acid metabolic process|methanesulfonic acid metabolism|methanesulphonic acid metabolism http://purl.obolibrary.org/obo/GO_0018926 CHEBI:28294 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28294 GO:0018925 biolink:BiologicalProcess m-cresol metabolic process The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes. MetaCyc:M-CRESOL-DEGRADATION-PWY|UM-BBD_pathwayID:mcr go-plus.json m-cresol metabolism|3-hydroxytoluene metabolism|meta-cresol metabolism|meta-cresol metabolic process|3-hydroxytoluene metabolic process http://purl.obolibrary.org/obo/GO_0018925 CHEBI:28293 biolink:ChemicalSubstance (S)-1-aminopropan-2-yl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28293 GO:0018920 biolink:BiologicalProcess glyphosate metabolic process The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond. UM-BBD_pathwayID:gly go-plus.json Roundup metabolic process|glyphosate metabolism|Roundup metabolism http://purl.obolibrary.org/obo/GO_0018920 GO:0018922 biolink:BiologicalProcess iprodione metabolic process The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium). UM-BBD_pathwayID:ipd go-plus.json iprodione metabolism http://purl.obolibrary.org/obo/GO_0018922 GO:0018921 biolink:BiologicalProcess 3-hydroxybenzyl alcohol metabolic process The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum. UM-BBD_pathwayID:mcr go-plus.json 3-hydroxybenzyl alcohol metabolism http://purl.obolibrary.org/obo/GO_0018921 CHEBI:77212 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77212 chebi_ph7_3 CHEBI:77211 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77211 chebi_ph7_3 UBERON:0006208 biolink:AnatomicalEntity auditory hillocks A collection of protruberances derived from pharyngeal arches 1 and 2 that develop into the folds of the pinna and gradually shift upwards and backwards to their final position on the head. go-plus.json auditory hillock of Hiss|auditory tubercles|hillock of Hiss|auricular hillock http://purl.obolibrary.org/obo/UBERON_0006208 UBERON:0006207 biolink:AnatomicalEntity aortico-pulmonary spiral septum The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions. go-plus.json septum aorticopulmonale|aortic septum|spiral septum|aortico-pulmonary septum|aorticopulmonary septum http://purl.obolibrary.org/obo/UBERON_0006207 UBERON:0006206 biolink:AnatomicalEntity iridocorneal angle Acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye[MP]. go-plus.json anterior chamber angle http://purl.obolibrary.org/obo/UBERON_0006206 CHEBI:77216 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77216 chebi_ph7_3 CHEBI:77215 biolink:ChemicalSubstance (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77215 chebi_ph7_3 CHEBI:77214 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77214 chebi_ph7_3 CHEBI:53242 biolink:ChemicalSubstance vinyl polymer macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53242 chebi_ph7_3 CHEBI:77213 biolink:ChemicalSubstance (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77213 chebi_ph7_3 CHEBI:77229 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z)-hexacosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77229 chebi_ph7_3 CHEBI:77228 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77228 chebi_ph7_3 GO:0018939 biolink:BiologicalProcess n-octane metabolic process The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System. UM-BBD_pathwayID:oct go-plus.json n-octane metabolism http://purl.obolibrary.org/obo/GO_0018939 CHEBI:28296 biolink:ChemicalSubstance L-alpha-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28296 GO:0018938 biolink:BiologicalProcess 2-nitropropane metabolic process The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol. MetaCyc:PWY-723|UM-BBD_pathwayID:npp go-plus.json 2-nitropropane metabolism http://purl.obolibrary.org/obo/GO_0018938 CHEBI:28295 biolink:ChemicalSubstance 2-deoxystreptamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28295 CHEBI:28297 biolink:ChemicalSubstance hydantoin-5-propionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28297 GO:0043902 biolink:BiologicalProcess obsolete positive regulation of multi-organism process OBSOLETE. Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. go-plus.json http://purl.obolibrary.org/obo/GO_0043902 GO:0018935 biolink:BiologicalProcess aerobic nitrilotriacetate metabolic process The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen. go-plus.json aerobic nitrilotriacetate metabolism http://purl.obolibrary.org/obo/GO_0018935 GO:0018934 biolink:BiologicalProcess nitrilotriacetate metabolic process The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment. UM-BBD_pathwayID:nta go-plus.json nitrilotriacetate metabolism http://purl.obolibrary.org/obo/GO_0018934 GO:0043901 biolink:BiologicalProcess obsolete negative regulation of multi-organism process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. go-plus.json http://purl.obolibrary.org/obo/GO_0043901 GO:0043904 biolink:MolecularActivity isochorismate pyruvate lyase activity Catalysis of the reaction: isochorismate = salicylate + pyruvate. MetaCyc:RXN-1981|RHEA:27874|EC:4.2.99.21 go-plus.json isochorismate-pyruvate lyase activity|IPL http://purl.obolibrary.org/obo/GO_0043904 GO:0018937 biolink:BiologicalProcess nitroglycerin metabolic process The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates. UM-BBD_pathwayID:ng|MetaCyc:P201-PWY go-plus.json NG metabolic process|nitroglycerin metabolism|NG metabolism http://purl.obolibrary.org/obo/GO_0018937 GO:0043903 biolink:BiologicalProcess regulation of biological process involved in symbiotic interaction Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association. go-plus.json regulation of symbiosis, encompassing mutualism through parasitism|regulation of interspecies interactions between organisms|regulation of symbiotic process http://purl.obolibrary.org/obo/GO_0043903 GO:0018936 biolink:BiologicalProcess anaerobic nitrilotriacetate metabolic process The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen. go-plus.json anaerobic nitrilotriacetate metabolism http://purl.obolibrary.org/obo/GO_0018936 GO:0018931 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018931 GO:0018930 biolink:BiologicalProcess 3-methylquinoline metabolic process The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring. UM-BBD_pathwayID:mqn go-plus.json 3-methylquinoline metabolism http://purl.obolibrary.org/obo/GO_0018930 GO:0018933 biolink:BiologicalProcess nicotine metabolic process The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. go-plus.json nicotine metabolism http://purl.obolibrary.org/obo/GO_0018933 GO:0043900 biolink:BiologicalProcess obsolete regulation of multi-organism process OBSOLETE. Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. go-plus.json http://purl.obolibrary.org/obo/GO_0043900 GO:0018932 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018932 CHEBI:77223 biolink:ChemicalSubstance (11Z,14Z,17Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77223 chebi_ph7_3 GO:0043909 biolink:MolecularActivity N-acetylcitrulline deacetylase activity Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate. RHEA:61092 go-plus.json acetylcitrulline deacetylase activity|N-acetyl-L-citrulline deacetylase activity http://purl.obolibrary.org/obo/GO_0043909 CHEBI:77222 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z)-octadecatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77222 chebi_ph7_3 CHEBI:77221 biolink:ChemicalSubstance (17Z)-hexacosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77221 chebi_ph7_3 CHEBI:77220 biolink:ChemicalSubstance (11Z,14Z)-icosadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77220 chebi_ph7_3 GO:0043906 biolink:MolecularActivity Ala-tRNA(Pro) hydrolase activity Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro). EC:3.1.1.- go-plus.json Ala-tRNAPro hydrolase activity http://purl.obolibrary.org/obo/GO_0043906 CHEBI:77227 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z)-tetracosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77227 chebi_ph7_3 GO:0043905 biolink:MolecularActivity Ser-tRNA(Thr) hydrolase activity Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr). EC:3.1.1.- go-plus.json Ser-tRNAThr hydrolase activity http://purl.obolibrary.org/obo/GO_0043905 CHEBI:77226 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77226 chebi_ph7_3 GO:0043908 biolink:MolecularActivity Ser(Gly)-tRNA(Ala) hydrolase activity Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala). EC:3.1.1.- go-plus.json Ser(Gly)-tRNAAla hydrolase activity http://purl.obolibrary.org/obo/GO_0043908 CHEBI:77225 biolink:ChemicalSubstance all-cis-docosa-7,10,13,16-tetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77225 chebi_ph7_3 CHEBI:77224 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77224 chebi_ph7_3 GO:0043907 biolink:MolecularActivity Cys-tRNA(Pro) hydrolase activity Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro). EC:3.1.1.- go-plus.json Cys-tRNAPro hydrolase activity|Cys-tRNA(Pro) deacetylase activity http://purl.obolibrary.org/obo/GO_0043907 NCBITaxon:6658 biolink:OrganismalEntity Branchiopoda go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6658 CHEBI:77239 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77239 NCBITaxon:6657 biolink:OrganismalEntity Crustacea go-plus.json crustaceans|crustaceans http://purl.obolibrary.org/obo/NCBITaxon_6657 NCBITaxon:6656 biolink:OrganismalEntity Arthropoda go-plus.json arthropods|arthropods http://purl.obolibrary.org/obo/NCBITaxon_6656 CHEBI:53226 biolink:ChemicalSubstance polyethylene macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53226 CHEBI:28266 biolink:ChemicalSubstance fluorene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28266 chebi_ph7_3 GO:0018909 biolink:BiologicalProcess dodecyl sulfate metabolic process The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants. UM-BBD_pathwayID:dds go-plus.json dodecyl sulfate metabolism|dodecyl sulphate metabolic process|dodecyl sulphate metabolism http://purl.obolibrary.org/obo/GO_0018909 GO:0018906 biolink:BiologicalProcess methyl tert-butyl ether metabolic process The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent. UM-BBD_pathwayID:mtb go-plus.json methyl tert-butyl ether metabolism http://purl.obolibrary.org/obo/GO_0018906 CHEBI:28262 biolink:ChemicalSubstance dimethyl sulfoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28262 chebi_ph7_3 GO:0018905 biolink:BiologicalProcess dimethyl ether metabolic process The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications. UM-BBD_pathwayID:dme go-plus.json methyl ether metabolic process|methyl ether metabolism|dimethyl ether metabolism http://purl.obolibrary.org/obo/GO_0018905 GO:0018908 biolink:BiologicalProcess organosulfide cycle A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle. UM-BBD_pathwayID:sulf go-plus.json organosulphide cycle http://purl.obolibrary.org/obo/GO_0018908 CHEBI:28265 biolink:ChemicalSubstance coenzyme F430 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28265 GO:0018907 biolink:BiologicalProcess dimethyl sulfoxide metabolic process The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing. UM-BBD_pathwayID:sulf go-plus.json dimethyl sulphoxide metabolism|DMSO metabolic process|DMSO metabolism|dimethyl sulfoxide metabolism|dimethyl sulphoxide metabolic process http://purl.obolibrary.org/obo/GO_0018907 CHEBI:28264 biolink:ChemicalSubstance 3-oxooctanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28264 GO:0043913 biolink:CellularComponent obsolete chromosome segregation-directing complex OBSOLETE. A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology. go-plus.json MreBCD complex|chromosome segregation directing complex|longitudinal peptidoglycan synthesis-directing complex http://purl.obolibrary.org/obo/GO_0043913 GO:0018902 biolink:BiologicalProcess 1,3-dichloro-2-propanol metabolic process The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers. UM-BBD_pathwayID:dcp go-plus.json DCP metabolic process|1,3-dichloro-2-propanol metabolism|DCP metabolism http://purl.obolibrary.org/obo/GO_0018902 GO:0043912 biolink:MolecularActivity D-lysine oxidase activity Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide. EC:1.4.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0043912 GO:0018901 biolink:BiologicalProcess 2,4-dichlorophenoxyacetic acid metabolic process The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. UM-BBD_pathwayID:2,4-d go-plus.json 2,4-D metabolic process|2,4-dichlorophenoxyacetic acid metabolism|2,4-D metabolism http://purl.obolibrary.org/obo/GO_0018901 GO:0043915 biolink:MolecularActivity L-seryl-tRNA(Sec) kinase activity Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec). EC:2.7.1.164|MetaCyc:RXN-10038|RHEA:25037 go-plus.json O-phosphoseryl-tRNA(Sec) kinase activity http://purl.obolibrary.org/obo/GO_0043915 GO:0018904 biolink:BiologicalProcess ether metabolic process The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds. go-plus.json organic ether metabolic process|ether metabolism|organic ether metabolism http://purl.obolibrary.org/obo/GO_0018904 goslim_pir CHEBI:28272 biolink:ChemicalSubstance beta-L-arabinofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28272 chebi_ph7_3 GO:0043914 biolink:MolecularActivity NADPH:sulfur oxidoreductase activity Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+. EC:1.8.1.18 go-plus.json coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity|NAD(P)H sulfur oxidoreductase activity|NAD(P)H:sulfur oxidoreductase activity|NAD(P)H elemental sulfur oxidoreductase activity|CoA-dependent NAD(P)H sulfur oxidoreductase activity|NAD(P)H sulphur oxidoreductase activity|NSR|NADPH:sulphur oxidoreductase activity http://purl.obolibrary.org/obo/GO_0043914 GO:0018903 biolink:BiologicalProcess 1,3-dichloropropene metabolic process The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes. UM-BBD_pathwayID:cpr go-plus.json 1,3-dichloropropene metabolism|gamma-chloroallylchloride metabolic process|1,3-dichloropropylene metabolic process|1,3-dichloropropylene metabolism|gamma-chloroallylchloride metabolism http://purl.obolibrary.org/obo/GO_0018903 GO:0043911 biolink:MolecularActivity D-lysine transaminase activity Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate. go-plus.json D-lysine aminotransferase activity http://purl.obolibrary.org/obo/GO_0043911 GO:0018900 biolink:BiologicalProcess dichloromethane metabolic process The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover. UM-BBD_pathwayID:dcm go-plus.json dichloromethane metabolism http://purl.obolibrary.org/obo/GO_0018900 GO:0043910 biolink:MolecularActivity ATP:coenzyme F420 adenylyltransferase activity Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate. MetaCyc:RXN-9385 go-plus.json ATP:coenzyme F420 adenyltransferase activity|coenzyme F390-A synthetase activity http://purl.obolibrary.org/obo/GO_0043910 CHEBI:77234 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z)-tetratriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77234 chebi_ph7_3 CHEBI:77233 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z)-dotriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77233 chebi_ph7_3 CHEBI:53225 biolink:ChemicalSubstance poly(alkylene) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53225 CHEBI:77232 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z)-triacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77232 chebi_ph7_3 NCBITaxon:89593 biolink:OrganismalEntity Craniata go-plus.json Craniata http://purl.obolibrary.org/obo/NCBITaxon_89593 CHEBI:53224 biolink:ChemicalSubstance poly(amide) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53224 CHEBI:77231 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z)-octacosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77231 chebi_ph7_3 GO:0043917 biolink:MolecularActivity ribose 1,5-bisphosphate isomerase activity Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate. MetaCyc:RXN-8801|EC:5.3.1.29|RHEA:32243 go-plus.json ribose-1,5-bisphosphate isomerase activity http://purl.obolibrary.org/obo/GO_0043917 GO:0043916 biolink:MolecularActivity DNA-7-methylguanine glycosylase activity Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site. MetaCyc:3.2.2.21-RXN|EC:3.2.2.21 go-plus.json http://purl.obolibrary.org/obo/GO_0043916 CHEBI:77237 biolink:ChemicalSubstance O-hexadecanedioyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77237 GO:0043919 biolink:MolecularActivity agmatine aminopropyltransferase activity Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine. EC:2.5.1.104 go-plus.json agmatine aminopropyl transferase activity http://purl.obolibrary.org/obo/GO_0043919 CHEBI:77236 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z)-octatriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77236 chebi_ph7_3 GO:0043918 biolink:MolecularActivity cadaverine aminopropyltransferase activity Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine. EC:2.5.1.104 go-plus.json cadaverine aminopropyl transferase activity http://purl.obolibrary.org/obo/GO_0043918 CHEBI:77235 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z)-hexatriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77235 chebi_ph7_3 PO:0025233 biolink:OntologyClass portion of embryo plant tissue A portion of plant tissue (PO:0009007) that is part of a plant embryo (PO:0009009). go-plus.json portion of embryo tissue (broad)|tejido embriónico vegetal (Spanish, exact)|植物胚性組織 の一部 (Japanese, exact)|portion of embryonic plant tissue (exact) http://purl.obolibrary.org/obo/PO_0025233 NCBITaxon:6669 biolink:OrganismalEntity Daphnia pulex go-plus.json common water flea http://purl.obolibrary.org/obo/NCBITaxon_6669 NCBITaxon:6668 biolink:OrganismalEntity Daphnia go-plus.json common water fleas|Daphniopsis http://purl.obolibrary.org/obo/NCBITaxon_6668 NCBITaxon:6665 biolink:OrganismalEntity Cladocera go-plus.json water flea|water fleas http://purl.obolibrary.org/obo/NCBITaxon_6665 CHEBI:43896 biolink:ChemicalSubstance alpha-D-mannose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_43896 CHEBI:28279 biolink:ChemicalSubstance 6-methylthiopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28279 chebi_ph7_3 GO:0018917 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018917 GO:0018916 biolink:BiologicalProcess nitrobenzene metabolic process The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline. UM-BBD_pathwayID:nb go-plus.json nitrobenzene metabolism http://purl.obolibrary.org/obo/GO_0018916 CHEBI:28273 biolink:ChemicalSubstance aldehydo-N-acetyl-D-mannosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28273 GO:0018919 biolink:BiologicalProcess gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health. UM-BBD_pathwayID:ghch|MetaCyc:GAMMAHEXCHLORDEG-PWY go-plus.json gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolism http://purl.obolibrary.org/obo/GO_0018919 CHEBI:28276 biolink:ChemicalSubstance (S)-3-hydroxyhexanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28276 GO:0018918 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018918 GO:0043924 biolink:MolecularActivity suramin binding Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms. go-plus.json Germanin binding http://purl.obolibrary.org/obo/GO_0043924 GO:0018913 biolink:BiologicalProcess anaerobic ethylbenzene metabolic process The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen. UM-BBD_pathwayID:ethb go-plus.json anaerobic ethylbenzene metabolism http://purl.obolibrary.org/obo/GO_0018913 GO:0043923 biolink:BiologicalProcess positive regulation by host of viral transcription Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA. go-plus.json positive regulation of viral transcription by host http://purl.obolibrary.org/obo/GO_0043923 GO:0018912 biolink:BiologicalProcess 1,4-dichlorobenzene metabolic process The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs. UM-BBD_pathwayID:dcz go-plus.json 1,4-dichlorobenzene metabolism http://purl.obolibrary.org/obo/GO_0018912 CHEBI:28283 biolink:ChemicalSubstance capsidiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28283 chebi_ph7_3 GO:0018915 biolink:BiologicalProcess ethylbenzene metabolic process The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels. UM-BBD_pathwayID:ethb2 go-plus.json ethylbenzene metabolism http://purl.obolibrary.org/obo/GO_0018915 GO:0043926 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043926 GO:0018914 biolink:BiologicalProcess chlorobenzene metabolic process The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone. UM-BBD_pathwayID:cb go-plus.json chlorobenzene metabolism http://purl.obolibrary.org/obo/GO_0018914 CHEBI:28282 biolink:ChemicalSubstance N-benzyloxycarbonyl-L-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28282 GO:0043925 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043925 GO:0043920 biolink:MolecularActivity aminopropylagmatine ureohydrolase activity Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea. RHEA:35827|EC:3.5.3.24 go-plus.json http://purl.obolibrary.org/obo/GO_0043920 CHEBI:77241 biolink:ChemicalSubstance 1-icosanoyl-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77241 CHEBI:77240 biolink:ChemicalSubstance alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_77240 chebi_ph7_3 GO:0043922 biolink:BiologicalProcess negative regulation by host of viral transcription Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription. go-plus.json negative regulation of viral transcription by host http://purl.obolibrary.org/obo/GO_0043922 GO:0018911 biolink:BiologicalProcess 1,2,4-trichlorobenzene metabolic process The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides. UM-BBD_pathwayID:tbz go-plus.json 1,2,4-trichlorobenzene metabolism http://purl.obolibrary.org/obo/GO_0018911 GO:0018910 biolink:BiologicalProcess benzene metabolic process The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation. go-plus.json benzene metabolism http://purl.obolibrary.org/obo/GO_0018910 GO:0043921 biolink:BiologicalProcess modulation by host of viral transcription Any process in which a host organism modulates the frequency, rate or extent of viral transcription. go-plus.json regulation of viral transcription by host|regulation by host of viral transcription http://purl.obolibrary.org/obo/GO_0043921 PO:0025228 biolink:OntologyClass valve A cardinal organ part that is a part of a plant structure that splits apart when the structure dehisces. go-plus.json valva (Spanish, exact)|弁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025228 GO:0043928 biolink:BiologicalProcess exonucleolytic catabolism of deadenylated mRNA The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail. go-plus.json http://purl.obolibrary.org/obo/GO_0043928 GO:0043927 biolink:BiologicalProcess exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap. go-plus.json http://purl.obolibrary.org/obo/GO_0043927 CHEBI:77248 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77248 CHEBI:53210 biolink:ChemicalSubstance O-propanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_53210 chebi_ph7_3 GO:0043929 biolink:BiologicalProcess primary ovarian follicle growth involved in double layer follicle stage Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis. go-plus.json primary ovarian follicle growth during double layer follicle stage http://purl.obolibrary.org/obo/GO_0043929 PO:0025223 biolink:OntologyClass vegetative shoot apex A shoot apex PO:0000037) that has as part a vegetative shoot apical meristem (PO:0008016). go-plus.json ápice vegetativo del epiblasto (epiblastema) (Spanish, exact)|栄養シュート頂、栄養枝頂 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025223 CHEBI:28245 biolink:ChemicalSubstance (S)-2-amino-6-oxopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28245 CHEBI:28247 biolink:ChemicalSubstance 11beta-hydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28247 chebi_ph7_3 UBERON:0006245 biolink:AnatomicalEntity humerus cartilage element A humerus endochondral element that is composed primarily of cartilage tissue. go-plus.json humeral cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006245 GO:0043935 biolink:BiologicalProcess sexual sporulation resulting in formation of a cellular spore The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0043935 GO:0043934 biolink:BiologicalProcess sporulation The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. Wikipedia:Spore go-plus.json http://purl.obolibrary.org/obo/GO_0043934 goslim_metagenomics|goslim_yeast CHEBI:28250 biolink:ChemicalSubstance 6-O-acetyl-beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28250 chebi_ph7_3 PR:000005663 biolink:Protein ciliary neurotrophic factor A protein that is a translation product of the human CNTF gene or a 1:1 ortholog thereof. go-plus.json CNTF http://purl.obolibrary.org/obo/PR_000005663 GO:0043937 biolink:BiologicalProcess regulation of sporulation Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0043937 GO:0043936 biolink:BiologicalProcess asexual sporulation resulting in formation of a cellular spore The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. go-plus.json asexual sporulation resulting in the formation of a viable spore|asexual reproduction resulting in the formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043936 UBERON:0006242 biolink:AnatomicalEntity gall bladder primordium A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006242 GO:0043931 biolink:BiologicalProcess ossification involved in bone maturation The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. go-plus.json ossification involved in skeletal development|ossification involved in bone modeling http://purl.obolibrary.org/obo/GO_0043931 UBERON:0006241 biolink:AnatomicalEntity future spinal cord go-plus.json presumptive spinal cord neural keel|presumptive spinal cord|presumptive spinal cord neural plate|presumptive spinal cord neural rod http://purl.obolibrary.org/obo/UBERON_0006241 CHEBI:77252 biolink:ChemicalSubstance 1,2-diarachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77252 UBERON:0006240 biolink:AnatomicalEntity future forebrain A presumptive structure that has the potential to develop into a forebrain. go-plus.json future prosencephalon|prosencephalon|presumptive prosencephalon|presumptive forebrain http://purl.obolibrary.org/obo/UBERON_0006240 CHEBI:77251 biolink:ChemicalSubstance (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77251 chebi_ph7_3 GO:0043930 biolink:BiologicalProcess primary ovarian follicle growth involved in primary follicle stage Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis. go-plus.json primary ovarian follicle growth during primary follicle stage http://purl.obolibrary.org/obo/GO_0043930 GO:0043933 biolink:BiologicalProcess protein-containing complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. go-plus.json cellular macromolecular complex organization|cellular macromolecular complex subunit organization|protein complex subunit organisation|macromolecular complex subunit organisation|protein complex subunit organization|macromolecular complex organization|macromolecular complex subunit organization|cellular macromolecular complex subunit organisation http://purl.obolibrary.org/obo/GO_0043933 CHEBI:77250 biolink:ChemicalSubstance pristanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77250 chebi_ph7_3 GO:0043932 biolink:BiologicalProcess ossification involved in bone remodeling The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli. go-plus.json ossification involved in bone remodelling http://purl.obolibrary.org/obo/GO_0043932 CHEBI:77256 biolink:ChemicalSubstance 1,1'-dioleyl 2,2'-dilysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77256 chebi_ph7_3 CHEBI:77255 biolink:ChemicalSubstance EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77255 CHEBI:77254 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77254 CHEBI:77253 biolink:ChemicalSubstance tetraoleoyl cardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77253 chebi_ph7_3 GO:0043939 biolink:BiologicalProcess negative regulation of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0043939 GO:0043938 biolink:BiologicalProcess positive regulation of sporulation Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0043938 CHEBI:77259 biolink:ChemicalSubstance trioleoyl 2-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77259 chebi_ph7_3 CHEBI:77258 biolink:ChemicalSubstance 1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77258 CHEBI:77257 biolink:ChemicalSubstance (2S)-2-methylpentadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77257 chebi_ph7_3 UBERON:0006246 biolink:AnatomicalEntity humerus pre-cartilage condensation A humerus endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json humeral pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006246 PO:0025297 biolink:OntologyClass seedling radicle A radicle (PO:0020031) that is part of a whole plant (PO:0000003) in the seedling development stage (PO:0007131). go-plus.json radícula de la plántula (Spanish, exact)|実生幼根 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025297 PO:0025296 biolink:OntologyClass plant embryo radicle A radicle (PO:0020031) that is part of a plant embryo (PO:0009009). go-plus.json 胚幼根 (Japanese, exact)|radícula del embrión (Spanish, exact)|embryonic radicle (exact) http://purl.obolibrary.org/obo/PO_0025296 CHEBI:28259 biolink:ChemicalSubstance (S)-3-hydroxyisobutyryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28259 GO:0043940 biolink:BiologicalProcess regulation of sexual sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0043940 CHEBI:28258 biolink:ChemicalSubstance vomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28258 chebi_ph7_3 CHEBI:28257 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28257 chebi_ph7_3 GO:0043946 biolink:BiologicalProcess obsolete positive regulation of catalytic activity in other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json up-regulation of enzyme activity in other organism during symbiotic interaction|activation of enzyme activity in other organism|up regulation of enzyme activity in other organism during symbiotic interaction|positive regulation of catalytic activity in other organism during symbiotic interaction|upregulation of enzyme activity in other organism during symbiotic interaction|activation of enzyme activity in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0043946 UBERON:0006234 biolink:AnatomicalEntity femur pre-cartilage condensation A femur endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json femoral pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006234 GO:0043945 biolink:BiologicalProcess positive regulation of asexual sporulation resulting in formation of a cellular spore Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0043945 UBERON:0006233 biolink:AnatomicalEntity female genital tubercle A differentiated genital tubercle that is part of a female reproductive system. go-plus.json genital tubercle of female http://purl.obolibrary.org/obo/UBERON_0006233 GO:0043948 biolink:BiologicalProcess obsolete induction by symbiont of host catalytic activity OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json upregulation by symbiont of host enzyme activity|up-regulation by symbiont of host enzyme activity|activation by symbiont of host enzyme activity|positive regulation by symbiont of host catalytic activity|positive regulation by symbiont of host enzyme activity|up regulation by symbiont of host enzyme activity|activation of host enzyme activity http://purl.obolibrary.org/obo/GO_0043948 UBERON:0006232 biolink:AnatomicalEntity facio-acoustic VII-VIII preganglion complex go-plus.json facio-acoustic preganglion complex http://purl.obolibrary.org/obo/UBERON_0006232 CHEBI:28261 biolink:ChemicalSubstance (+)-alpha-pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28261 chebi_ph7_3 GO:0043947 biolink:BiologicalProcess obsolete positive regulation by host of symbiont catalytic activity OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json up-regulation by host of symbiont enzyme activity|activation by host of symbiont enzyme activity|positive regulation by host of symbiont enzyme activity|up regulation by host of symbiont enzyme activity|activation of symbiont enzyme activity|upregulation by host of symbiont enzyme activity http://purl.obolibrary.org/obo/GO_0043947 CHEBI:28260 biolink:ChemicalSubstance galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28260 GO:0043942 biolink:BiologicalProcess negative regulation of sexual sporulation resulting in formation of a cellular spore Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0043942 CHEBI:77263 biolink:ChemicalSubstance 6-deoxy-6-sulfo-D-fructofuranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77263 UBERON:0006230 biolink:AnatomicalEntity extrinsic ocular pre-muscle mass go-plus.json http://purl.obolibrary.org/obo/UBERON_0006230 GO:0043941 biolink:BiologicalProcess positive regulation of sexual sporulation resulting in formation of a cellular spore Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0043941 GO:0043944 biolink:BiologicalProcess negative regulation of asexual sporulation resulting in formation of a cellular spore Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0043944 CHEBI:77261 biolink:ChemicalSubstance 6-deoxy-6-sulfo-D-fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_77261 GO:0043943 biolink:BiologicalProcess regulation of asexual sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0043943 CHEBI:77267 biolink:ChemicalSubstance 3-sulfopropanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77267 CHEBI:77265 biolink:ChemicalSubstance 3-sulfolactaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_77265 UBERON:0006239 biolink:AnatomicalEntity future central tendon A tendon that has the potential to develop into a central tendon. go-plus.json cranial derivative of septum transversum|cranial part of septum transversum http://purl.obolibrary.org/obo/UBERON_0006239 UBERON:0006238 biolink:AnatomicalEntity future brain The embryonic precursor of the brain. go-plus.json encephalon|brain rudiment|embryonic brain|presumptive brain http://purl.obolibrary.org/obo/UBERON_0006238 GO:0043949 biolink:BiologicalProcess regulation of cAMP-mediated signaling Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. go-plus.json regulation of cAMP-mediated signalling http://purl.obolibrary.org/obo/GO_0043949 UBERON:0006236 biolink:AnatomicalEntity tetrapod frontal bone primordium go-plus.json frontal bone primordium http://purl.obolibrary.org/obo/UBERON_0006236 CHEBI:77269 biolink:ChemicalSubstance dTDP-beta-L-evernitrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_77269 UBERON:0006235 biolink:AnatomicalEntity foregut-midgut junction An anatomical junctions that overlaps the foregut and midgut. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006235 CHEBI:77268 biolink:ChemicalSubstance pristanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77268 chebi_ph7_3 CHEBI:28229 biolink:ChemicalSubstance N(omega)-methyl-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28229 PO:0025281 biolink:OntologyClass pollen A microgametophyte (PO:0025280) that develops from a microspore (PO:0020048) is located in a pollen sac (PO:0025277). go-plus.json pollen grain (exact)|polen (Spanish, exact)|花粉 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025281 CHEBI:28228 biolink:ChemicalSubstance S-acetylphosphopantotheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28228 CHEBI:28223 biolink:ChemicalSubstance adenosine 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28223 PO:0025280 biolink:OntologyClass microgametophyte A whole plant (PO:0000003) in the gametophyte development stage (PO:0028003) that produces plant sperm cells (PO:0000084). go-plus.json microgametofito (Spanish, exact)|小配偶体 (Japanese, exact)|male gametophyte (exact) http://purl.obolibrary.org/obo/PO_0025280 CHEBI:28222 biolink:ChemicalSubstance 1,2,4-trichlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28222 chebi_ph7_3 CHEBI:28225 biolink:ChemicalSubstance D-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28225 GO:0043951 biolink:BiologicalProcess negative regulation of cAMP-mediated signaling Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. go-plus.json negative regulation of cAMP-mediated signalling http://purl.obolibrary.org/obo/GO_0043951 GO:0043950 biolink:BiologicalProcess positive regulation of cAMP-mediated signaling Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. go-plus.json positive regulation of cAMP-mediated signalling http://purl.obolibrary.org/obo/GO_0043950 CHEBI:28220 biolink:ChemicalSubstance 2,6-dihydroxypseudooxynicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28220 GO:0043957 biolink:MolecularActivity acryloyl-CoA reductase (NADP+) activity Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+. KEGG_REACTION:R00919|MetaCyc:RXN-9087|EC:1.3.1.84|RHEA:26454 go-plus.json acryloyl-CoA reductase (NADPH) activity|AMP-dependent synthetase and ligase|AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase|acrylyl-CoA reductase (NADPH) activity|acetyl-coenzyme A synthetase/GroES-like domain|acetyl-coenzyme A synthetase|enoyl-CoA hydratase/isomerase http://purl.obolibrary.org/obo/GO_0043957 UBERON:0006222 biolink:AnatomicalEntity future diencephalon The foremost region of the future forebrain that develops into the diencephalon. go-plus.json presumptive diencephalon http://purl.obolibrary.org/obo/UBERON_0006222 GO:0043956 biolink:MolecularActivity 3-hydroxypropionyl-CoA dehydratase activity Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O. RHEA:26518|MetaCyc:RXN-6383|EC:4.2.1.116 go-plus.json 3-hydroxy propionyl-CoA dehydratase activity|AMP-dependent synthetase and ligase|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase/GroES-like domain|acetyl-coenzyme A synthetase|enoyl-CoA hydratase/isomerase http://purl.obolibrary.org/obo/GO_0043956 GO:0043959 biolink:MolecularActivity L-erythro-3-methylmalyl-CoA lyase activity Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA. EC:4.1.3.24 go-plus.json HpcH/HpaI aldolase http://purl.obolibrary.org/obo/GO_0043959 GO:0043958 biolink:MolecularActivity acryloyl-CoA reductase activity Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein. EC:1.3.99.3|MetaCyc:RXN-8568|RHEA:34471 go-plus.json acryloyl-coenzyme A reductase activity|propionyl-CoA dehydrogenase|acrylyl-CoA reductase (NADH) http://purl.obolibrary.org/obo/GO_0043958 CHEBI:77274 biolink:ChemicalSubstance 1-alkyl-3-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77274 chebi_ph7_3 GO:0043953 biolink:BiologicalProcess protein transport by the Tat complex The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex. go-plus.json twin-arginine translocation pathway|protein secretion by the TAT complex|protein translocation by the TAT complex|protein translocation by the twin-arginine translocation complex http://purl.obolibrary.org/obo/GO_0043953 GO:0043952 biolink:BiologicalProcess protein transport by the Sec complex The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide. go-plus.json protein secretion by the Sec complex|protein translocation by the Sec complex http://purl.obolibrary.org/obo/GO_0043952 CHEBI:77272 biolink:ChemicalSubstance 1,3-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77272 chebi_ph7_3 GO:0043955 biolink:MolecularActivity 3-hydroxypropionyl-CoA synthetase activity Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate. EC:6.2.1.36|RHEA:26534 go-plus.json 3-hydroxy propionyl-CoA synthetase activity|acetyl-coenzyme A synthetase/GroES-like domain|AMP-dependent synthetase and ligase|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase|enoyl-CoA hydratase/isomerase http://purl.obolibrary.org/obo/GO_0043955 GO:0043954 biolink:BiologicalProcess cellular component maintenance The organization process that preserves a cellular component in a stable functional or structural state. go-plus.json cellular component maintenance at cellular level http://purl.obolibrary.org/obo/GO_0043954 CHEBI:77271 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77271 CHEBI:77277 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77277 CHEBI:77276 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77276 CHEBI:77275 biolink:ChemicalSubstance (2R)-pristanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77275 chebi_ph7_3 UBERON:0006227 biolink:AnatomicalEntity ethmoid bone primordium go-plus.json http://purl.obolibrary.org/obo/UBERON_0006227 PO:0025279 biolink:OntologyClass megagametophyte A whole plant in the gametophyte development stage (PO:0028003) that produces only plant egg cells (PO:0020094). go-plus.json megagametofito (Spanish, exact)|female gametophyte (exact)|大配偶体 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025279 CHEBI:77279 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77279 UBERON:0006224 biolink:AnatomicalEntity elbow joint primordium go-plus.json http://purl.obolibrary.org/obo/UBERON_0006224 PO:0025277 biolink:OntologyClass pollen sac A microsporangium that is part of a sporophyll and where the pollen grains develop and are located after they develop. go-plus.json saco polínico (Spanish, exact)|Zea microsporangium (narrow)|花粉のう (Japanese, exact)|Poaceae microsporangium (narrow)|anther lobe (narrow) http://purl.obolibrary.org/obo/PO_0025277 PO:0025275 biolink:OntologyClass procambium A portion of meristem tissue (PO:0009013) that undergoes differentiation to form the primary vascular tissue (PO:0025408). go-plus.json procambio (Spanish, exact)|前形成層 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025275 PO:0025272 biolink:OntologyClass plant ovary replum A portion of ovary placenta tissue (PO:0020001) which divides a plant ovary (PO:0009072) into two or more chambers, and develops from contact of the placental tissue from opposite sides of the plant ovary early in gynoecium development (GO:0048467). go-plus.json placental septum (exact)|子房隔膜 (Japanese, exact)|false ovary septum (exact)|ovary dissepiment (broad)|replo (replum) del ovario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025272 GO:0043960 biolink:MolecularActivity L-erythro-3-methylmalyl-CoA dehydratase activity Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0043960 CHEBI:28233 biolink:ChemicalSubstance 2,4,6-trihydroxybenzophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28233 GO:0043962 biolink:BiologicalProcess obsolete negative regulation by host of symbiont adenylate cyclase-mediated signal transduction OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0043962 GO:0043961 biolink:MolecularActivity succinyl-CoA:(R)-citramalate CoA-transferase activity Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA. RHEA:38279|EC:2.8.3.20|MetaCyc:RXN-8966 go-plus.json succinyl-CoA:R-citramalate CoA transferase|succinyl-CoA:(R)-citramalate CoA transferase activity|L-carnitine dehydratase/bile acid-inducible protein F http://purl.obolibrary.org/obo/GO_0043961 CHEBI:28230 biolink:ChemicalSubstance hesperetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28230 chebi_ph7_3 CHEBI:28232 biolink:ChemicalSubstance D-ribose 5-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28232 GO:0043968 biolink:BiologicalProcess histone H2A acetylation The modification of histone H2A by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0043968 CHEBI:77281 biolink:ChemicalSubstance dTDP-N-hydroxy-beta-L-evernosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77281 GO:0043967 biolink:BiologicalProcess histone H4 acetylation The modification of histone H4 by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0043967 CHEBI:77280 biolink:ChemicalSubstance dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_77280 CHEBI:211 biolink:ChemicalSubstance (3S)-3-isopropenyl-6-oxoheptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_211 chebi_ph7_3 UBERON:0006211 biolink:AnatomicalEntity buccopharyngeal membrane The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx. go-plus.json pharyngeal membrane|oral membrane|oral plate|oropharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0006211 UBERON:0006210 biolink:AnatomicalEntity body-wall mesenchyme go-plus.json http://purl.obolibrary.org/obo/UBERON_0006210 GO:0043969 biolink:BiologicalProcess histone H2B acetylation The modification of histone H2B by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0043969 CHEBI:43858 biolink:ChemicalSubstance L-vinylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_43858 GO:0043964 biolink:BiologicalProcess induction by symbiont of host adenylate cyclase-mediated signal transduction Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host adenylate cyclase-mediated signal transduction http://purl.obolibrary.org/obo/GO_0043964 CHEBI:77285 biolink:ChemicalSubstance dTDP-beta-L-evernosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77285 GO:0043963 biolink:BiologicalProcess modulation by symbiont of host adenylate cyclase-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0043963 CHEBI:77284 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77284 chebi_ph7_3 GO:0043966 biolink:BiologicalProcess histone H3 acetylation The modification of histone H3 by the addition of an acetyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0043966 CHEBI:77283 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77283 chebi_ph7_3 GO:0043965 biolink:BiologicalProcess suppression by symbiont of host adenylate cyclase-mediated signal transduction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host adenylate cyclase-mediated signal transduction http://purl.obolibrary.org/obo/GO_0043965 UBERON:0006219 biolink:AnatomicalEntity deltoid pre-muscle mass go-plus.json http://purl.obolibrary.org/obo/UBERON_0006219 CHEBI:77288 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77288 chebi_ph7_3 CHEBI:77287 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77287 chebi_ph7_3 UBERON:0006218 biolink:AnatomicalEntity common atrial chamber go-plus.json http://purl.obolibrary.org/obo/UBERON_0006218 CHEBI:77286 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77286 chebi_ph7_3 UBERON:0006217 biolink:AnatomicalEntity cloacal membrane The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings. go-plus.json membrana cloacalis|embryonic cloacal membrane http://purl.obolibrary.org/obo/UBERON_0006217 PO:0025269 biolink:OntologyClass collective organ part structure A collective plant structure (PO:0025497) composed of two or more cardinal organ parts (PO:0025001) that are part of adjacent plant organs (PO:0009008) and any associated portions of plant tissue (PO:0009007). go-plus.json órgano colectivo de una parte de la estructura (Spanish, exact)|集合的器官の部分構造 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025269 UBERON:0006215 biolink:AnatomicalEntity rhombic lip the posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system go-plus.json cerebellar primordium|rostral rhombic lip|cerebellar anlage|cerebellum primordium|future cerebellum|dorsal part of alar plate of metencephalon|presumptive cerebellum http://purl.obolibrary.org/obo/UBERON_0006215 UBERON:0006214 biolink:AnatomicalEntity carpus pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a carpal bone. go-plus.json carpal pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006214 PO:0025268 biolink:OntologyClass fruit septum A septum that divides a cavity or mass of tissue in a fruit and develops from an ovary septum. go-plus.json septo del fruto (Spanish, exact)|fruit dissepiment (broad)|果実隔壁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025268 PO:0025267 biolink:OntologyClass fruit replum A portion of fruit placenta tissue (PO:0004535) that divides a fruit (PO:0009001) into two or more chambers and develops from a plant ovary replum (PO:0025272). go-plus.json 果実隔膜 (Japanese, exact)|replum del fruto (Spanish, exact)|fruit dissepiment (broad) http://purl.obolibrary.org/obo/PO_0025267 UBERON:0006213 biolink:AnatomicalEntity carpus cartilage element A cartilaginous condensation that has the potential to develop into a carpal bone. go-plus.json carpal cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006213 GO:0004367 biolink:MolecularActivity glycerol-3-phosphate dehydrogenase [NAD+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+. KEGG_REACTION:R00842|MetaCyc:1.1.1.8-RXN|Reactome:R-HSA-75889|EC:1.1.1.8|RHEA:11092 go-plus.json glycerol-3-phosphate dehydrogenase (NAD) activity|L-glycerophosphate dehydrogenase activity|NAD-dependent glycerol phosphate dehydrogenase activity|NAD-alpha-glycerophosphate dehydrogenase activity|glycerol phosphate dehydrogenase (NAD) activity|alpha-glycerophosphate dehydrogenase (NAD) activity|glycerol 1-phosphate dehydrogenase activity|L-glycerol phosphate dehydrogenase activity|hydroglycerophosphate dehydrogenase activity|L-alpha-glycerophosphate dehydrogenase activity|alpha-glycerol phosphate dehydrogenase (NAD) activity|NAD-linked glycerol 3-phosphate dehydrogenase activity|NADH-dihydroxyacetone phosphate reductase activity|glycerophosphate dehydrogenase (NAD) activity|L-alpha-glycerol phosphate dehydrogenase activity|NAD-L-glycerol-3-phosphate dehydrogenase activity|NAD-dependent glycerol-3-phosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004367 GO:0004366 biolink:MolecularActivity glycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. Reactome:R-HSA-549112|MetaCyc:RXN-1381|RHEA:15325|Reactome:R-HSA-75886|Reactome:R-HSA-1482695|EC:2.3.1.15 go-plus.json sn-glycerol-3-phosphate acyltransferase activity|3-glycerophosphate acyltransferase activity|acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity|glycerophosphate acyltransferase activity|glycerol phosphate transacylase activity|sn-glycerol 3-phosphate acyltransferase activity|ACP:sn-glycerol-3-phosphate acyltransferase activity|glycerol phosphate acyltransferase activity|glycerophosphate transacylase activity|alpha-glycerophosphate acyltransferase activity|glycerol 3-phosphate acyltransferase activity http://purl.obolibrary.org/obo/GO_0004366 GO:0004369 biolink:MolecularActivity glycerol-3-phosphate oxidase activity Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2). KEGG_REACTION:R00846|EC:1.1.3.21|RHEA:18369|MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN go-plus.json sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity|glycerol-1-phosphate oxidase activity|glycerol phosphate oxidase activity|alpha-glycerophosphate oxidase activity|L-alpha-glycerophosphate oxidase activity|L-alpha-glycerol-3-phosphate oxidase activity http://purl.obolibrary.org/obo/GO_0004369 GO:0004368 biolink:MolecularActivity glycerol-3-phosphate dehydrogenase (quinone) activity Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. MetaCyc:RXN0-5260|RHEA:18977|EC:1.1.5.3|Reactome:R-HSA-188467|MetaCyc:RXN-9927 go-plus.json FAD-dependent glycerol-3-phosphate dehydrogenase|flavin-linked glycerol-3-phosphate dehydrogenase|sn-glycerol-3-phosphate dehydrogenase activity|glycerol-3-phosphate CoQ reductase|glycerophosphate dehydrogenase activity|sn-glycerol-3-phosphate:quinone oxidoreductase activity|L-glycerophosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004368 GO:0004363 biolink:MolecularActivity glutathione synthase activity Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate. MetaCyc:GLUTATHIONE-SYN-RXN|Reactome:R-HSA-174394|RHEA:13557|KEGG_REACTION:R00497|EC:6.3.2.3|Reactome:R-HSA-5602901 go-plus.json GSH synthetase activity|glutathione synthetase activity|gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0004363 GO:0004362 biolink:MolecularActivity glutathione-disulfide reductase (NADPH) activity Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+. EC:1.8.1.7|RHEA:11740|Reactome:R-HSA-3323079|MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN|Reactome:R-HSA-71682 go-plus.json GSSG reductase activity|oxidized glutathione reduction|NADPH-GSSG reductase activity|NADPH-glutathione reductase activity|glutathione-disulfide reductase activity|glutathione-disulphide reductase activity|NADPH:oxidized-glutathione oxidoreductase activity|glutathione reductase activity|glutathione S-reductase activity|glutathione:NADP+ oxidoreductase activity|GSH reductase activity http://purl.obolibrary.org/obo/GO_0004362 GO:0004365 biolink:MolecularActivity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+. EC:1.2.1.12|Reactome:R-HSA-70449|Reactome:R-HSA-70482|RHEA:10300|MetaCyc:GAPOXNPHOSPHN-RXN go-plus.json GAPDH activity|triosephosphate dehydrogenase activity|NADH-glyceraldehyde phosphate dehydrogenase activity|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde phosphate dehydrogenase (NAD)|phosphoglyceraldehyde dehydrogenase activity|NAD-dependent glyceraldehyde phosphate dehydrogenase activity|glyceraldehyde-3-P-dehydrogenase activity|D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)|3-phosphoglyceraldehyde dehydrogenase activity|dehydrogenase, glyceraldehyde phosphate http://purl.obolibrary.org/obo/GO_0004365 GO:0004364 biolink:MolecularActivity glutathione transferase activity Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Reactome:R-HSA-176054|MetaCyc:GSHTRAN-RXN|Reactome:R-HSA-9026901|Reactome:R-HSA-9026780|Reactome:R-HSA-3301943|Reactome:R-HSA-9026911|Reactome:R-HSA-5423653|Reactome:R-HSA-176059|Reactome:R-HSA-9026777|EC:2.5.1.18 go-plus.json glutathione S-aryltransferase activity|S-(hydroxyalkyl)glutathione lyase activity|glutathione S-transferase activity|glutathione S-alkyltransferase activity|glutathione conjugation reaction|RX:glutathione R-transferase activity|glutathione S-alkyl transferase activity|glutathione S-aralkyltransferase activity http://purl.obolibrary.org/obo/GO_0004364 GO:0004361 biolink:MolecularActivity glutaryl-CoA dehydrogenase activity Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor. UM-BBD_reactionID:r0198|EC:1.3.8.6|RHEA:13389|MetaCyc:GLUTARYL-COA-DEHYDROGENASE-RXN|Reactome:R-HSA-71046 go-plus.json glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)|glutaryl coenzyme A dehydrogenase activity|glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0004361 GO:0102911 biolink:MolecularActivity (-)-secoisolariciresinol dehydrogenase activity Catalysis of the reaction: (-)-secoisolariciresinol + NAD <=> H+ + (-)-lactol + NADH. MetaCyc:RXN-8680 go-plus.json http://purl.obolibrary.org/obo/GO_0102911 GO:0004360 biolink:MolecularActivity glutamine-fructose-6-phosphate transaminase (isomerizing) activity Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate. Reactome:R-HSA-449715|RHEA:13237|MetaCyc:L-GLN-FRUCT-6-P-AMINOTRANS-RXN|Reactome:R-HSA-4085027|KEGG_REACTION:R00768|EC:2.6.1.16 go-plus.json L-glutamine-D-fructose-6-phosphate amidotransferase activity|glucosamine-6-phosphate synthase activity|glucosamine-6-phosphate isomerase (glutamine-forming) activity|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity|L-glutamine:D-fructose-6-phosphate isomerase (deaminating)|GlcN6P synthase activity|hexosephosphate aminotransferase activity|glucosamine 6-phosphate synthase activity|D-fructose-6-phosphate amidotransferase activity|glucosaminephosphate isomerase http://purl.obolibrary.org/obo/GO_0004360 GO:0102910 biolink:MolecularActivity dirigent protein activity Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O. MetaCyc:RXN-8677 go-plus.json http://purl.obolibrary.org/obo/GO_0102910 GO:0102913 biolink:MolecularActivity 3-aminomethylindole N-methyltransferase activity Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine. MetaCyc:RXN-8686|RHEA:52268 go-plus.json http://purl.obolibrary.org/obo/GO_0102913 GO:0102912 biolink:MolecularActivity (-)-lactol dehydrogenase activity Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH. MetaCyc:RXN-8681 go-plus.json http://purl.obolibrary.org/obo/GO_0102912 GO:0102915 biolink:MolecularActivity piperitol synthase activity Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 <=> (+)-piperitol + NADP + 2 H2O. MetaCyc:RXN-8695 go-plus.json http://purl.obolibrary.org/obo/GO_0102915 GO:0102914 biolink:MolecularActivity N-methyl-3-aminomethylindole N-methyltransferase activity Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine. MetaCyc:RXN-8687|RHEA:52272 go-plus.json http://purl.obolibrary.org/obo/GO_0102914 GO:0102917 biolink:MolecularActivity (S)-reticuline 7-O-methyltransferase activity Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine. EC:2.1.1.291|MetaCyc:RXN-8700|RHEA:10444 go-plus.json http://purl.obolibrary.org/obo/GO_0102917 GO:0102916 biolink:MolecularActivity sesamin synthase activity Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O. MetaCyc:RXN-8696|EC:1.14.19.74 go-plus.json http://purl.obolibrary.org/obo/GO_0102916 GO:0102919 biolink:MolecularActivity 5,6-dimethylbenzimidazole synthase activity Catalysis of the reaction: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid. EC:1.13.11.79|MetaCyc:RXN-8771|RHEA:27345 go-plus.json http://purl.obolibrary.org/obo/GO_0102919 GO:0102918 biolink:MolecularActivity (R)-reticuline 7-O-methyltransferase activity Catalysis of the reaction: (R)-reticulinium(1+) + S-adenosyl-L-methionine <=> (R)-laudanine(1+) + S-adenosyl-L-homocysteine + H+. EC:2.1.1.291|MetaCyc:RXN-8701|RHEA:38907 go-plus.json http://purl.obolibrary.org/obo/GO_0102918 GO:0004378 biolink:MolecularActivity GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage. EC:2.4.1.132|RHEA:29515|MetaCyc:2.4.1.132-RXN go-plus.json GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity|glycolipid 3-alpha-mannosyltransferase activity|mannosyltransferase II activity|GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase II http://purl.obolibrary.org/obo/GO_0004378 GO:0004377 biolink:MolecularActivity GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. EC:2.4.1.131|RHEA:29523|MetaCyc:2.4.1.131-RXN go-plus.json guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity|GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity|glycolipid 2-alpha-mannosyltransferase activity|GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity|oligosaccharide-lipid mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0004377 GO:0004379 biolink:MolecularActivity glycylpeptide N-tetradecanoyltransferase activity Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide. MetaCyc:2.3.1.97-RXN|Reactome:R-HSA-2534087|EC:2.3.1.97|RHEA:15521|Reactome:R-HSA-184392 go-plus.json myristoylating enzymes|myristoyl-coenzyme A:protein N-myristoyl transferase activity|myristoyl-CoA-protein N-myristoyltransferase activity|peptide N-tetradecanoyltransferase activity|peptide N-myristoyltransferase activity|tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity|protein N-myristoyltransferase activity|N-myristoyltransferase activity http://purl.obolibrary.org/obo/GO_0004379 GO:0004374 biolink:MolecularActivity obsolete glycine cleavage system OBSOLETE. Catalysis of the reactions: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + carbon dioxide (CO2), followed by S-aminomethyldihydrolipoylprotein + (6S)-tetrahydrofolate = dihydrolipoylprotein + (6R)-5,10-methylenetetrahydrofolate + ammonia. Made up of two components, aminomethyltransferase and glycine dehydrogenase (decarboxylating). go-plus.json glycine synthase|glycine cleavage system http://purl.obolibrary.org/obo/GO_0004374 GO:0004373 biolink:MolecularActivity glycogen (starch) synthase activity Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1). MetaCyc:2.4.1.11-RXN|Reactome:R-HSA-3322009|Reactome:R-HSA-3322041|Reactome:R-HSA-3322001|Reactome:R-HSA-3828061|EC:2.4.1.11|RHEA:18549|Reactome:R-HSA-3858506 go-plus.json glycogen (starch) synthetase activity|UDPG-glycogen synthetase activity|UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|UDP-glucose-glycogen glucosyltransferase activity|UDP-glycogen synthase activity|UDPG-glycogen transglucosylase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-glycogen glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0004373 GO:0004376 biolink:MolecularActivity glycolipid mannosyltransferase activity Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. Reactome:R-HSA-162821|Reactome:R-HSA-162873 go-plus.json glycolipid mannosyl transferase activity http://purl.obolibrary.org/obo/GO_0004376 GO:0004375 biolink:MolecularActivity glycine dehydrogenase (decarboxylating) activity Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2. RHEA:24304|EC:1.4.4.2|MetaCyc:GCVP-RXN|Reactome:R-HSA-5693967 go-plus.json glycine-cleavage complex|glycine decarboxylase activity|P-protein|glycine-cleavage complex P-protein activity|glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)|glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)|protein P1|glycine cleavage system P-protein activity http://purl.obolibrary.org/obo/GO_0004375 GO:0004370 biolink:MolecularActivity glycerol kinase activity Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+). KEGG_REACTION:R00847|Reactome:R-HSA-75887|RHEA:21644|EC:2.7.1.30|MetaCyc:GLYCEROL-KIN-RXN go-plus.json glycerokinase activity|glycerol kinase (phosphorylating)|ATP:glycerol-3-phosphotransferase activity|GK|glyceric kinase activity|ATP:glycerol 3-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004370 GO:0102920 biolink:MolecularActivity acyl coenzyme A: isopenicillin N acyltransferase activity Catalysis of the reaction: octanoyl-CoA + isopenicillin N + H2O <=> H+ + coenzyme A + penicillin K + L-2-aminoadipate. MetaCyc:RXN-8809|EC:2.3.1.164 go-plus.json http://purl.obolibrary.org/obo/GO_0102920 GO:0102922 biolink:MolecularActivity phenylpropanoyltransferase activity Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A. RHEA:42488|MetaCyc:RXN-8857 go-plus.json http://purl.obolibrary.org/obo/GO_0102922 GO:0004372 biolink:MolecularActivity glycine hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. Reactome:R-HSA-200735|Reactome:R-HSA-5694137|MetaCyc:GLYOHMETRANS-RXN|Reactome:R-HSA-200651|Reactome:R-HSA-71249|RHEA:15481|EC:2.1.2.1 go-plus.json serine aldolase activity|serine hydroxymethylase activity|serine transhydroxymethylase activity|5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity|allothreonine aldolase activity|L-serine hydroxymethyltransferase activity|serine hydroxymethyltransferase activity http://purl.obolibrary.org/obo/GO_0004372 GO:0004371 biolink:MolecularActivity glycerone kinase activity Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+). EC:2.7.1.29|MetaCyc:GLYCERONE-KINASE-RXN|KEGG_REACTION:R01011|RHEA:15773 go-plus.json acetol kinase (phosphorylating)|acetol kinase activity|dihydroxyacetone kinase activity|ATP:glycerone phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004371 GO:0102921 biolink:MolecularActivity mannosylglycerate synthase activity Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate <=> H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP. EC:2.4.1.269|MetaCyc:RXN-8849|RHEA:30639 go-plus.json http://purl.obolibrary.org/obo/GO_0102921 GO:0102924 biolink:MolecularActivity gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide. MetaCyc:RXN-886 go-plus.json http://purl.obolibrary.org/obo/GO_0102924 GO:0102923 biolink:MolecularActivity 3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A. RHEA:33687|MetaCyc:RXN-8859 go-plus.json http://purl.obolibrary.org/obo/GO_0102923 GO:0102926 biolink:MolecularActivity solanidine glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP. MetaCyc:RXN-8882 go-plus.json http://purl.obolibrary.org/obo/GO_0102926 GO:0102925 biolink:MolecularActivity solanine UDP-galactose galactosyltransferase activity Catalysis of the reaction: UDP-D-galactose + solanidine = H+ + gamma-solanine + UDP. MetaCyc:RXN-8875 go-plus.json http://purl.obolibrary.org/obo/GO_0102925 GO:0102928 biolink:MolecularActivity beta-solanine rhamnosyltransferase activity Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP. MetaCyc:RXN-8884 go-plus.json http://purl.obolibrary.org/obo/GO_0102928 GO:0102927 biolink:MolecularActivity beta-chaconine rhamnosyltransferase activity Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP. MetaCyc:RXN-8883 go-plus.json http://purl.obolibrary.org/obo/GO_0102927 GO:0102929 biolink:MolecularActivity lachrymatory factor synthase activity Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide. MetaCyc:RXN-8911 go-plus.json http://purl.obolibrary.org/obo/GO_0102929 GO:0004349 biolink:MolecularActivity glutamate 5-kinase activity Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+). MetaCyc:GLUTKIN-RXN|KEGG_REACTION:R00239|RHEA:14877|EC:2.7.2.11 go-plus.json gamma-glutamyl kinase activity|ATP:L-glutamate 5-phosphotransferase activity|glutamate kinase activity|gamma-glutamate kinase activity|ATP:gamma-L-glutamate phosphotransferase activity|ATP-L-glutamate 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004349 GO:0004348 biolink:MolecularActivity glucosylceramidase activity Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine. Reactome:R-HSA-1861789|MetaCyc:GLUCOSYLCERAMIDASE-RXN|EC:3.2.1.45|RHEA:13269|Reactome:R-HSA-1861788|Reactome:R-HSA-1605591 go-plus.json glucocerebrosidase activity|glucosphingosine glucosylhydrolase activity|psychosine hydrolase activity|beta-D-glucocerebrosidase activity|GlcCer-beta-glucosidase activity|glucosylsphingosine beta-D-glucosidase activity|beta-glucosylceramidase activity|D-glucosyl-N-acylsphingosine glucohydrolase activity|glucosylcerebrosidase activity|acid beta-glucosidase activity|glucosylsphingosine beta-glucosidase activity|ceramide glucosidase activity|beta-glucocerebrosidase activity http://purl.obolibrary.org/obo/GO_0004348 GO:0004345 biolink:MolecularActivity glucose-6-phosphate dehydrogenase activity Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+. MetaCyc:GLU6PDEHYDROG-RXN|RHEA:15841|Reactome:R-HSA-70377|EC:1.1.1.49 go-plus.json NADP-dependent glucose 6-phosphate dehydrogenase activity|Zwischenferment|glucose 6-phosphate dehydrogenase (NADP) activity|6-phosphoglucose dehydrogenase activity|glucose-6-phosphate 1-dehydrogenase activity|D-glucose 6-phosphate dehydrogenase activity|zwischenferment|D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity|GDH|G6PDH|6-phosphoglucose dehydrogenas|NADP-glucose-6-phosphate dehydrogenase activity|G6PD activity|Entner-doudoroff enzyme http://purl.obolibrary.org/obo/GO_0004345 GO:0004344 biolink:MolecularActivity glucose dehydrogenase activity Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor. KEGG_REACTION:R00305|MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:24540|EC:1.1.99.10 go-plus.json glucose dehydrogenase (Aspergillus) activity|glucose dehydrogenase (decarboxylating)|D-glucose:(acceptor) 1-oxidoreductase|D-glucose:acceptor 1-oxidoreductase|glucose dehydrogenase (acceptor) activity http://purl.obolibrary.org/obo/GO_0004344 GO:0004347 biolink:MolecularActivity glucose-6-phosphate isomerase activity Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate. RHEA:11816|MetaCyc:PGLUCISOM-RXN|Reactome:R-HSA-70475|EC:5.3.1.9|Reactome:R-HSA-70471 go-plus.json oxoisomerase activity|hexosephosphate isomerase activity|phosphohexomutase activity|D-glucose-6-phosphate aldose-ketose-isomerase activity|phosphoglucoisomerase activity|hexose phosphate isomerase activity|phosphohexose isomerase activity|hexose monophosphate isomerase activity|D-glucose-6-phosphate ketol-isomerase activity|glucose phosphate isomerase activity|phosphosaccharomutase activity|phosphoglucose isomerase activity|phosphohexoisomerase activity http://purl.obolibrary.org/obo/GO_0004347 GO:0004346 biolink:MolecularActivity glucose-6-phosphatase activity Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate. Reactome:R-HSA-3266566|Reactome:R-HSA-3282876|KEGG_REACTION:R00303|Reactome:R-HSA-3274540|Reactome:R-HSA-3262512|RHEA:16689|EC:3.1.3.9|Reactome:R-HSA-71825|MetaCyc:GLUCOSE-6-PHOSPHATASE-RXN go-plus.json D-glucose-6-phosphate phosphohydrolase activity|glucose 6-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0004346 GO:0004341 biolink:MolecularActivity gluconolactonase activity Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate. MetaCyc:GLUCONOLACT-RXN|RHEA:10440|EC:3.1.1.17 go-plus.json lactonase activity|aldonolactonase activity|D-glucono-1,5-lactone lactonohydrolase activity|gulonolactonase activity|glucono-delta-lactonase activity http://purl.obolibrary.org/obo/GO_0004341 GO:0004340 biolink:MolecularActivity glucokinase activity Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate. Reactome:R-HSA-70420|RHEA:17825|EC:2.7.1.2|Reactome:R-HSA-5621918|MetaCyc:GLUCOKIN-RXN|Reactome:R-HSA-5621888 go-plus.json glucokinase (phosphorylating)|glucose kinase activity|ATP:D-glucose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004340 GO:0004343 biolink:MolecularActivity glucosamine 6-phosphate N-acetyltransferase activity Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+). Reactome:R-HSA-449734|KEGG_REACTION:R02058|EC:2.3.1.4|RHEA:10292|MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN go-plus.json N-acetylglucosamine-6-phosphate synthase activity|phosphoglucosamine transacetylase activity|aminodeoxyglucosephosphate acetyltransferase activity|acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity|D-glucosamine-6-P N-acetyltransferase activity|glucosamine-6-phosphate acetylase activity|phosphoglucosamine acetylase activity|phosphoglucosamine N-acetylase activity|glucosamine 6-phosphate acetylase activity|glucosamine-phosphate N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004343 GO:0004342 biolink:MolecularActivity glucosamine-6-phosphate deaminase activity Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+). KEGG_REACTION:R00765|Reactome:R-HSA-6799604|MetaCyc:GLUCOSAMINE-6-P-DEAMIN-RXN|RHEA:12172|EC:3.5.99.6 go-plus.json 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)|glucosamine-6-phosphate isomerase activity|glucosaminephosphate isomerase|phosphoglucosaminisomerase activity|glucosamine phosphate deaminase activity|aminodeoxyglucosephosphate isomerase activity|phosphoglucosamine isomerase activity|GlcN6P deaminase activity http://purl.obolibrary.org/obo/GO_0004342 GO:0102931 biolink:MolecularActivity (Z,E)-alpha- farnesene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid. MetaCyc:RXN-8931 go-plus.json http://purl.obolibrary.org/obo/GO_0102931 GO:0102930 biolink:MolecularActivity 4-hydroxybenzoate geranyltransferase activity Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid. MetaCyc:RXN-8920|RHEA:27854|EC:2.5.1.93 go-plus.json http://purl.obolibrary.org/obo/GO_0102930 GO:0102933 biolink:MolecularActivity GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate. MetaCyc:RXN-8953|RHEA:36779|EC:2.6.1.102 go-plus.json http://purl.obolibrary.org/obo/GO_0102933 GO:0102932 biolink:MolecularActivity pterocarpan reductase activity Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP. MetaCyc:RXN-8936 go-plus.json http://purl.obolibrary.org/obo/GO_0102932 GO:0102935 biolink:MolecularActivity gypsogenin-UDP-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP. MetaCyc:RXN-9012 go-plus.json http://purl.obolibrary.org/obo/GO_0102935 GO:0102934 biolink:MolecularActivity costunolide synthase activity Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP. EC:1.14.14.150|MetaCyc:RXN-8971|RHEA:28230 go-plus.json http://purl.obolibrary.org/obo/GO_0102934 GO:0018989 biolink:BiologicalProcess apolysis The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells. Wikipedia:Apolysis go-plus.json http://purl.obolibrary.org/obo/GO_0018989 GO:0102937 biolink:MolecularActivity 16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP. MetaCyc:RXN-9014 go-plus.json http://purl.obolibrary.org/obo/GO_0102937 GO:0102936 biolink:MolecularActivity gypsogenate-UDP-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP. MetaCyc:RXN-9013 go-plus.json http://purl.obolibrary.org/obo/GO_0102936 GO:0102939 biolink:MolecularActivity 3-methoxy-5-hydroxytoluene O-methyltransferase activity Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine. MetaCyc:RXN-9018 go-plus.json http://purl.obolibrary.org/obo/GO_0102939 GO:0018986 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018986 GO:0102938 biolink:MolecularActivity orcinol O-methyltransferase activity Catalysis of the reaction: orcinol + S-adenosyl-L-methionine = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine. MetaCyc:RXN-9017|EC:2.1.1.6 go-plus.json http://purl.obolibrary.org/obo/GO_0102938 GO:0018985 biolink:BiologicalProcess pronuclear envelope synthesis Synthesis and ordering of the envelope of pronuclei. go-plus.json http://purl.obolibrary.org/obo/GO_0018985 GO:0018988 biolink:BiologicalProcess obsolete molting cycle, protein-based cuticle OBSOLETE. The periodic shedding of part or all of a protein-based cuticle, which is then replaced by a new protein-based cuticle. A cuticle is the outer layer of an animal which acts to prevent water loss. go-plus.json protein-based cuticle molting cycle http://purl.obolibrary.org/obo/GO_0018988 GO:0018987 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018987 GO:0018982 biolink:BiologicalProcess vanillin metabolic process The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin. UM-BBD_pathwayID:van go-plus.json vanillic aldehyde metabolic process|vanillin metabolism|vanillic aldehyde metabolism http://purl.obolibrary.org/obo/GO_0018982 GO:0018981 biolink:BiologicalProcess triethanolamine metabolic process The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent. UM-BBD_pathwayID:tea go-plus.json triethanolamine metabolism http://purl.obolibrary.org/obo/GO_0018981 GO:0018984 biolink:BiologicalProcess naphthalenesulfonate metabolic process The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene. UM-BBD_pathwayID:nphs go-plus.json naphthalenesulphonate metabolic process|naphthalenesulphonate metabolism|naphthalenesulfonate metabolism http://purl.obolibrary.org/obo/GO_0018984 GO:0018983 biolink:BiologicalProcess Z-phenylacetaldoxime metabolic process The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants. UM-BBD_pathwayID:pao go-plus.json Z-phenylacetaldoxime metabolism http://purl.obolibrary.org/obo/GO_0018983 GO:0018980 biolink:BiologicalProcess 2,4,5-trichlorophenoxyacetic acid metabolic process The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns. UM-BBD_pathwayID:2,4,5-t go-plus.json 2,4,5-trichlorophenoxyacetic acid metabolism|2,4,5-T metabolism|2,4,5-T metabolic process http://purl.obolibrary.org/obo/GO_0018980 GO:0004359 biolink:MolecularActivity glutaminase activity Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3. EC:3.5.1.2|MetaCyc:GLUTAMIN-RXN|Reactome:R-HSA-70609|RHEA:15889 go-plus.json L-glutaminase activity|L-glutamine amidohydrolase activity|glutaminase I|glutamine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0004359 GO:0004356 biolink:MolecularActivity glutamate-ammonia ligase activity Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate. MetaCyc:GLUTAMINESYN-RXN|Reactome:R-HSA-70606|KEGG_REACTION:R00253|RHEA:16169|EC:6.3.1.2 go-plus.json L-glutamate:ammonia ligase (ADP-forming)|glutamylhydroxamic synthetase activity|L-glutamine synthetase activity|glutamine synthetase activity http://purl.obolibrary.org/obo/GO_0004356 GO:0004355 biolink:MolecularActivity glutamate synthase (NADPH) activity Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+. MetaCyc:GLUGLNSYN-PWY|MetaCyc:GLUTSYN-PWY|MetaCyc:GLUTAMATESYN-RXN|EC:1.4.1.13|KEGG_REACTION:R00114|RHEA:15501 go-plus.json L-glutamate:NADP+ oxidoreductase (transaminating)|glutamine-ketoglutaric aminotransferase activity|L-glutamate synthetase activity|NADPH GOGAT|glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity|L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity|NADPH-linked glutamate synthase|GOGAT activity|NADPH-glutamate synthase activity|NADPH-dependent glutamate synthase activity|glutamate synthetase (NADP) activity|L-glutamate synthase activity|glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity http://purl.obolibrary.org/obo/GO_0004355 GO:0004358 biolink:MolecularActivity glutamate N-acetyltransferase activity Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine. KEGG_REACTION:R02282|MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.35|RHEA:15349 go-plus.json glutamate acetyltransferase activity|acetylglutamate synthetase activity|2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|acetylglutamate-acetylornithine transacetylase activity|N-acetylglutamate synthetase activity|acetylornithine glutamate acetyltransferase activity|ornithine acetyltransferase activity|N-acetyl-L-glutamate synthetase activity|N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|ornithine transacetylase activity|acetylglutamic synthetase activity|acetylglutamic-acetylornithine transacetylase activity|acetylornithinase activity|N-acetylglutamate synthase activity|alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004358 GO:0004357 biolink:MolecularActivity glutamate-cysteine ligase activity Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate. RHEA:13285|MetaCyc:GLUTCYSLIG-RXN|Reactome:R-HSA-5602892|KEGG_REACTION:R00894|Reactome:R-HSA-174367|EC:6.3.2.2 go-plus.json gamma-glutamyl-L-cysteine synthetase activity|L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity|gamma-glutamylcysteinyl synthetase activity|gamma-glutamylcysteine synthetase activity http://purl.obolibrary.org/obo/GO_0004357 GO:0004352 biolink:MolecularActivity glutamate dehydrogenase (NAD+) activity Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+. EC:1.4.1.2|MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN|RHEA:15133 go-plus.json NAD-dependent glutamate dehydrogenase activity|NAD-glutamate dehydrogenase activity|NAD-dependent glutamic dehydrogenase activity|NAD:glutamate oxidoreductase activity|glutamate dehydrogenase (NAD)|L-glutamate:NAD+ oxidoreductase (deaminating)|NAD-specific glutamate dehydrogenase activity|glutamic dehydrogenase activity|L-glutamate dehydrogenase|NADH-linked glutamate dehydrogenase activity|NAD-linked glutamic dehydrogenase activity|NAD-linked glutamate dehydrogenase activity|NAD-specific glutamic dehydrogenase activity|glutamic acid dehydrogenase|glutamate oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004352 GO:0004351 biolink:MolecularActivity glutamate decarboxylase activity Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. EC:4.1.1.15|Reactome:R-HSA-888572|MetaCyc:GLUTDECARBOX-RXN|Reactome:R-HSA-888577|RHEA:17785 go-plus.json gamma-glutamate decarboxylase activity|L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)|L-glutamic decarboxylase activity|L-aspartate-alpha-decarboxylase activity|L-glutamate alpha-decarboxylase activity|L-glutamic acid decarboxylase activity|cysteic acid decarboxylase activity|aspartic alpha-decarboxylase|L-glutamate 1-carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0004351 GO:0004354 biolink:MolecularActivity glutamate dehydrogenase (NADP+) activity Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+. EC:1.4.1.4|MetaCyc:GLUTSYNIII-PWY|MetaCyc:GLUTDEHYD-RXN|RHEA:11612 go-plus.json NAD(P)-glutamate dehydrogenase activity|L-glutamate:NADP+ oxidoreductase (deaminating)|NAD(P)H-dependent glutamate dehydrogenase activity|L-glutamate dehydrogenase|glutamic dehydrogenase activity|L-glutamic acid dehydrogenase activity|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))|glutamic acid dehydrogenase http://purl.obolibrary.org/obo/GO_0004354 GO:0102940 biolink:MolecularActivity phloroglucinol O-methyltransferase activity Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine. MetaCyc:RXN-9020 go-plus.json http://purl.obolibrary.org/obo/GO_0102940 GO:0004353 biolink:MolecularActivity glutamate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+. EC:1.4.1.3|Reactome:R-HSA-70589|MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN|MetaCyc:GLUTAMATE-SYN2-PWY|Reactome:R-HSA-70600 go-plus.json glutamic dehydrogenase activity|L-glutamate:NAD(P)+ oxidoreductase (deaminating)|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+) http://purl.obolibrary.org/obo/GO_0004353 GO:0102942 biolink:MolecularActivity 3,5-dimethoxyphenol O-methyltransferase activity Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine. MetaCyc:RXN-9022 go-plus.json http://purl.obolibrary.org/obo/GO_0102942 GO:0102941 biolink:MolecularActivity 3,5-dihydroxyanisole O-methyltransferase activity Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine. MetaCyc:RXN-9021 go-plus.json http://purl.obolibrary.org/obo/GO_0102941 GO:0004350 biolink:MolecularActivity glutamate-5-semialdehyde dehydrogenase activity Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH. RHEA:19541|MetaCyc:GLUTSEMIALDEHYDROG-RXN|EC:1.2.1.41|KEGG_REACTION:R03313 go-plus.json glutamyl-gamma-semialdehyde dehydrogenase activity|glutamate-phosphate reductase activity|glutamate-gamma-semialdehyde dehydrogenase activity|gamma-glutamylphosphate reductase activity|glutamylphosphate reductase activity|L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|glutamate semialdehyde dehydrogenase activity|beta-glutamylphosphate reductase activity|gamma-glutamyl phosphate reductase activity http://purl.obolibrary.org/obo/GO_0004350 GO:0102944 biolink:MolecularActivity medicagenate UDP-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside. MetaCyc:RXN-9035 go-plus.json http://purl.obolibrary.org/obo/GO_0102944 GO:0102943 biolink:MolecularActivity trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate. RHEA:28182|EC:5.3.3.17|MetaCyc:RXN-9031 go-plus.json http://purl.obolibrary.org/obo/GO_0102943 GO:0102946 biolink:MolecularActivity soyasapogenol E UDP-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside. MetaCyc:RXN-9038 go-plus.json http://purl.obolibrary.org/obo/GO_0102946 GO:0102945 biolink:MolecularActivity soyasapogenol B UDP-glucosyl transferase activity Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside. MetaCyc:RXN-9037 go-plus.json http://purl.obolibrary.org/obo/GO_0102945 CHEBI:53291 biolink:ChemicalSubstance 2-halophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_53291 chebi_ph7_3 GO:0102948 biolink:MolecularActivity luteolin C-glucosyltransferase activity Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor. MetaCyc:RXN-9081 go-plus.json http://purl.obolibrary.org/obo/GO_0102948 GO:0102947 biolink:MolecularActivity (+)-delta-cadinene-8-hydroxylase activity Catalysis of the reaction: H+ + (+)-delta-cadinene + NADPH + O2 <=> 8-hydroxy-(+)-delta-cadinene + NADP + H2O. MetaCyc:RXN-9045 go-plus.json http://purl.obolibrary.org/obo/GO_0102947 GO:0018997 biolink:MolecularActivity obsolete electron transfer carrier OBSOLETE. (Was not defined before being made obsolete). go-plus.json electron transfer carrier http://purl.obolibrary.org/obo/GO_0018997 GO:0018996 biolink:BiologicalProcess molting cycle, collagen and cuticulin-based cuticle The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans. go-plus.json collagen and cuticulin-based cuticle molting cycle http://purl.obolibrary.org/obo/GO_0018996 GO:0102949 biolink:MolecularActivity 1,2-rhamnosyltransferase activity Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor. MetaCyc:RXN-9082 go-plus.json http://purl.obolibrary.org/obo/GO_0102949 GO:0018999 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018999 GO:0018998 biolink:CellularComponent obsolete metaxin OBSOLETE. (Was not defined before being made obsolete). go-plus.json metaxin http://purl.obolibrary.org/obo/GO_0018998 GO:0018993 biolink:BiologicalProcess somatic sex determination The determination of sex and sexual phenotypes in an organism's soma. go-plus.json http://purl.obolibrary.org/obo/GO_0018993 GO:0018992 biolink:BiologicalProcess germ-line sex determination The determination of sex and sexual phenotype in an organism's germ line. go-plus.json http://purl.obolibrary.org/obo/GO_0018992 GO:0018995 biolink:CellularComponent host cellular component Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection. Wikipedia:Host_(biology) go-plus.json host organism http://purl.obolibrary.org/obo/GO_0018995 GO:0018994 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018994 GO:0018991 biolink:BiologicalProcess oviposition The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water. Wikipedia:Oviposition go-plus.json egg laying|post-mating oviposition|egg-laying http://purl.obolibrary.org/obo/GO_0018991 GO:0018990 biolink:BiologicalProcess ecdysis, chitin-based cuticle The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0018990 PO:0025222 biolink:OntologyClass reproductive shoot apex A shoot apex that has as part a reproductive shoot apical meristem. go-plus.json ápice reproductivo del epiblasto (epiblastema) (Spanish, exact)|生殖シュート頂、茎頂 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025222 GO:0004327 biolink:MolecularActivity obsolete formaldehyde dehydrogenase (glutathione) activity OBSOLETE. Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+. go-plus.json formaldehyde dehydrogenase (glutathione) activity http://purl.obolibrary.org/obo/GO_0004327 GO:0004326 biolink:MolecularActivity tetrahydrofolylpolyglutamate synthase activity Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1). Reactome:R-HSA-200682|Reactome:R-HSA-197958|EC:6.3.2.17|Reactome:R-HSA-200681|RHEA:10580|MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN go-plus.json folylpolyglutamate synthase activity|FPGS activity|tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)|folate polyglutamate synthetase activity|folylpolyglutamyl synthetase activity|folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity|folylpoly(gamma-glutamate) synthase activity|folylpoly-gamma-glutamate synthase activity|formyltetrahydropteroyldiglutamate synthetase activity|N10-formyltetrahydropteroyldiglutamate synthetase activity|folylpolyglutamate synthetase activity|tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)|N(10)-formyltetrahydropteroyldiglutamate synthetase activity|tetrahydrofolate synthase activity|tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity http://purl.obolibrary.org/obo/GO_0004326 GO:0004329 biolink:MolecularActivity formate-tetrahydrofolate ligase activity Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate. Reactome:R-HSA-5696839|MetaCyc:FORMATETHFLIG-RXN|RHEA:20221|EC:6.3.4.3|Reactome:R-HSA-6801456|Reactome:R-HSA-200711 go-plus.json 10-formyltetrahydrofolate synthetase activity|tetrahydrofolic formylase activity|formyltetrahydrofolate synthetase activity|tetrahydrofolate formylase activity|formate:tetrahydrofolate ligase (ADP-forming)|10-formyl-THF synthetase activity http://purl.obolibrary.org/obo/GO_0004329 GO:0004328 biolink:MolecularActivity formamidase activity Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+). RHEA:21948|EC:3.5.1.49|MetaCyc:FORMAMIDASE-RXN|KEGG_REACTION:R00524|UM-BBD_reactionID:r0873 go-plus.json formamide amidohydrolase activity|formamide hydrolase activity http://purl.obolibrary.org/obo/GO_0004328 GO:0004323 biolink:MolecularActivity obsolete multicopper ferroxidase iron transport mediator activity OBSOLETE. Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O. go-plus.json multicopper ferroxidase iron transport mediator activity http://purl.obolibrary.org/obo/GO_0004323 GO:0004322 biolink:MolecularActivity ferroxidase activity Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O. Reactome:R-HSA-1562603|Reactome:R-HSA-917891|MetaCyc:RXN0-1483|Reactome:R-HSA-5691107|RHEA:11148|Reactome:R-HSA-917933|Reactome:R-HSA-5621402|EC:1.16.3.1|Reactome:R-HSA-1562626|Reactome:R-HSA-1562604 go-plus.json ferroxidase I|Fe(II):oxygen oxidoreductase activity|multicopper ferroxidase iron transport mediator activity|hephaestin|ceruloplasmin|iron(II): oxygen oxidoreductase activity|HEPH|ferro:O2 oxidoreductase activity|ferroxidase, iron II:oxygen oxidoreductase activity|caeruloplasmin http://purl.obolibrary.org/obo/GO_0004322 GO:0004325 biolink:MolecularActivity ferrochelatase activity Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX. Reactome:R-HSA-189465|KEGG_REACTION:R00310|RHEA:22584|MetaCyc:PROTOHEMEFERROCHELAT-RXN|EC:4.99.1.1 go-plus.json protoheme ferro-lyase (protoporphyrin-forming)|protoheme ferro-lyase activity|ferro-protoporphyrin chelatase activity|heme synthetase activity|protoheme ferrolyase activity|iron chelatase activity|heme synthase activity http://purl.obolibrary.org/obo/GO_0004325 GO:0004324 biolink:MolecularActivity ferredoxin-NADP+ reductase activity Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+. MetaCyc:1.18.1.2-RXN|RHEA:20125|EC:1.18.1.2 go-plus.json reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity|ferredoxin-NADP-oxidoreductase activity|TPNH-ferredoxin reductase activity|ferredoxin-NADP reductase activity|ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity|NADP:ferredoxin oxidoreductase activity|ferredoxin-TPN reductase activity|ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity|ferredoxin-NADP oxidoreductase activity|ferredoxin:NADP+ oxidoreductase activity|NADPH:ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004324 GO:0004321 biolink:MolecularActivity fatty-acyl-CoA synthase activity Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+. EC:2.3.1.86|RHEA:22896|MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN go-plus.json yeast fatty acid synthase activity|fatty acyl CoA synthase activity|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing) http://purl.obolibrary.org/obo/GO_0004321 GO:0004320 biolink:MolecularActivity oleoyl-[acyl-carrier-protein] hydrolase activity Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate. EC:3.1.2.14|MetaCyc:PWY-5142|RHEA:15057|MetaCyc:3.1.2.14-RXN go-plus.json oleoyl-acyl-carrier-protein hydrolase|oleoyl-acyl carrier protein thioesterase activity|oleoyl-ACP thioesterase activity|oleoyl-[acyl-carrier protein] hydrolase activity|oleoyl-ACP hydrolase activity http://purl.obolibrary.org/obo/GO_0004320 GO:0018968 biolink:BiologicalProcess tetrahydrofuran metabolic process The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems. UM-BBD_pathwayID:thf go-plus.json THF metabolism|tetrahydrofuran metabolism|THF metabolic process http://purl.obolibrary.org/obo/GO_0018968 GO:0018967 biolink:BiologicalProcess tetrachloroethylene metabolic process The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent. UM-BBD_pathwayID:tce2 go-plus.json tetrachloroethylene metabolism|tetrachloroethene metabolic process|tetrachloroethene metabolism http://purl.obolibrary.org/obo/GO_0018967 GO:0018969 biolink:BiologicalProcess thiocyanate metabolic process The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries. UM-BBD_pathwayID:thc|MetaCyc:P581-PWY go-plus.json thiocyanic acid metabolic process|thiocyanic acid metabolism|thiocyanate metabolism http://purl.obolibrary.org/obo/GO_0018969 GO:0018964 biolink:BiologicalProcess propylene metabolic process The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals. UM-BBD_pathwayID:pro go-plus.json propylene metabolism http://purl.obolibrary.org/obo/GO_0018964 GO:0018963 biolink:BiologicalProcess phthalate metabolic process The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses. UM-BBD_pathwayID:pth go-plus.json phthalic acid metabolism|phthalic acid metabolic process|phthalate metabolism http://purl.obolibrary.org/obo/GO_0018963 GO:0018966 biolink:BiologicalProcess styrene metabolic process The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen. UM-BBD_pathwayID:sty go-plus.json styrene metabolism http://purl.obolibrary.org/obo/GO_0018966 GO:0018965 biolink:BiologicalProcess s-triazine compound metabolic process The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms. UM-BBD_pathwayID:tria go-plus.json s-triazine compound metabolism http://purl.obolibrary.org/obo/GO_0018965 GO:0018960 biolink:BiologicalProcess 4-nitrophenol metabolic process The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion. UM-BBD_pathwayID:nphe go-plus.json p-nitrophenol metabolic process|p-nitrophenol metabolism|4-nitrophenol metabolism http://purl.obolibrary.org/obo/GO_0018960 GO:0018962 biolink:BiologicalProcess 3-phenylpropionate metabolic process The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins. UM-BBD_pathwayID:ppa go-plus.json phenylpropanoate metabolic process|hydrocinnamic acid metabolism|hydrocinnamic acid metabolic process|phenylpropanoate metabolism|3-phenylpropionate metabolism http://purl.obolibrary.org/obo/GO_0018962 GO:0018961 biolink:BiologicalProcess pentachlorophenol metabolic process The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms. UM-BBD_pathwayID:pcp go-plus.json pentachlorophenol metabolism|PCP metabolic process|PCP metabolism http://purl.obolibrary.org/obo/GO_0018961 PO:0025212 biolink:OntologyClass leaf pavement cell An epidermal pavement cell that is part of a leaf epidermis. go-plus.json 葉被蓋細胞 (Japanese, exact)|célula de pavimento de la hoja (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025212 GO:0004338 biolink:MolecularActivity glucan exo-1,3-beta-glucosidase activity Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose. MetaCyc:3.2.1.58-RXN|EC:3.2.1.58 go-plus.json glucan 1,3-beta-glucosidase activity|exo-beta-1,3-D-glucanase activity|exo-1,3-beta-glucosidase activity|exo (1->3)-beta-glucanase activity|exo-beta-1,3-glucanase activity|exo-1,3-beta-D-glucanase activity|beta-1,3-glucan exo-hydrolase activity|exo-beta-(1->3)-glucanohydrolase activity|1,3-beta-glucan glucohydrolase activity|exo-beta-(1->3)-D-glucanase activity|exo-1,3-beta-glucanase activity http://purl.obolibrary.org/obo/GO_0004338 GO:0004337 biolink:MolecularActivity geranyltranstransferase activity Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate. Reactome:R-HSA-191303|Reactome:R-HSA-8870469|RHEA:19361|MetaCyc:FPPSYN-RXN|EC:2.5.1.10|KEGG_REACTION:R02003 go-plus.json farnesylpyrophosphate synthetase activity|geranyl transferase I|farnesyl-diphosphate synthase activity|geranyltransferase activity|farnesyl diphosphate synthetase activity|farnesyl pyrophosphate synthetase activity|FPP synthetase activity|geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity http://purl.obolibrary.org/obo/GO_0004337 GO:0004339 biolink:MolecularActivity glucan 1,4-alpha-glucosidase activity Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. MetaCyc:3.2.1.3-RXN|EC:3.2.1.3 go-plus.json exo-1,4-alpha-glucosidase activity|gamma-amylase activity|1,4-alpha-D-glucan glucohydrolase activity|amyloglucosidase activity|gamma-1,4-glucan glucohydrolase activity|glucoamylase activity|glucose amylase activity|lysosomal alpha-glucosidase activity http://purl.obolibrary.org/obo/GO_0004339 GO:0004334 biolink:MolecularActivity fumarylacetoacetase activity Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+). Reactome:R-HSA-71181|EC:3.7.1.2|UM-BBD_reactionID:r0107|MetaCyc:FUMARYLACETOACETASE-RXN|RHEA:10244|KEGG_REACTION:R01364 go-plus.json fumarylacetoacetate hydrolase activity|beta-diketonase activity|4-fumarylacetoacetate fumarylhydrolase activity http://purl.obolibrary.org/obo/GO_0004334 GO:0004333 biolink:MolecularActivity fumarate hydratase activity Catalysis of the reaction: (S)-malate = fumarate + H(2)O. MetaCyc:FUMHYDR-RXN|RHEA:12460|Reactome:R-HSA-451033|KEGG_REACTION:R01082|EC:4.2.1.2|Reactome:R-HSA-70982 go-plus.json (S)-malate hydro-lyase activity|(S)-malate hydro-lyase (fumarate-forming)|L-malate hydro-lyase activity|fumarase activity http://purl.obolibrary.org/obo/GO_0004333 GO:0004336 biolink:MolecularActivity galactosylceramidase activity Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine. RHEA:14297|Reactome:R-HSA-1606564|MetaCyc:GALACTOSYLCERAMIDASE-RXN|EC:3.2.1.46 go-plus.json galactocerebrosidase activity|ceramide galactosidase activity|D-galactosyl-N-acylsphingosine galactohydrolase activity|galactocerebroside beta-galactosidase activity|galactocerebroside galactosidase activity|galactocerebroside-beta-D-galactosidase activity|lactosylceramidase I|beta-galactosylceramidase activity|galactosylceramide beta-galactosidase activity|galactosylceramidase I|galcerase activity|cerebroside galactosidase activity|cerebroside beta-galactosidase activity|galactosylcerebrosidase activity|lactosylceramidase activity|beta-galactocerebrosidase activity http://purl.obolibrary.org/obo/GO_0004336 GO:0004335 biolink:MolecularActivity galactokinase activity Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+). KEGG_REACTION:R01092|Reactome:R-HSA-70355|Reactome:R-HSA-5610026|MetaCyc:GALACTOKIN-RXN|EC:2.7.1.6|RHEA:13553 go-plus.json ATP:D-galactose 1-phosphotransferase activity|galactokinase (phosphorylating)|ATP:D-galactose-1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004335 OBO:ddanat#develops_from biolink:OntologyClass develops_from develops_from go-plus.json http://purl.obolibrary.org/obo/ddanat#develops_from GO:0004330 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004330 GO:0004332 biolink:MolecularActivity fructose-bisphosphate aldolase activity Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate. Reactome:R-HSA-71496|Reactome:R-HSA-71495|RHEA:14729|MetaCyc:F16ALDOLASE-RXN|EC:4.1.2.13 go-plus.json aldolase activity|fructose-1,6-bisphosphate triosephosphate-lyase activity|phosphofructoaldolase activity|fructose 1,6-diphosphate aldolase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity|1,6-diphosphofructose aldolase activity|fructoaldolase activity|ketose 1-phosphate aldolase activity|fructose 1-phosphate aldolase activity|fructose 1-monophosphate aldolase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)|zymohexase activity|fructose diphosphate aldolase activity|SMALDO|diphosphofructose aldolase activity http://purl.obolibrary.org/obo/GO_0004332 GO:0004331 biolink:MolecularActivity fructose-2,6-bisphosphate 2-phosphatase activity Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate. Reactome:R-HSA-5628905|RHEA:17289|MetaCyc:3.1.3.46-RXN|Reactome:R-HSA-70262|EC:3.1.3.46 go-plus.json beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity|fructose-2,6-bisphosphatase activity|D-fructose-2,6-bisphosphate 2-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004331 GO:0018979 biolink:BiologicalProcess trichloroethylene metabolic process The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent. UM-BBD_pathwayID:tce go-plus.json TCE metabolic process|trichloroethene metabolic process|trichloroethene metabolism|TCE metabolism|trichloroethylene metabolism http://purl.obolibrary.org/obo/GO_0018979 GO:0018978 biolink:BiologicalProcess anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen. UM-BBD_pathwayID:ddt2 go-plus.json anaerobic DDT metabolism|anaerobic DDT metabolic process|anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism http://purl.obolibrary.org/obo/GO_0018978 GO:0018975 biolink:BiologicalProcess anaerobic 2,4,6-trinitrotoluene metabolic process The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen. UM-BBD_pathwayID:tnt2 go-plus.json anaerobic 2,4,6-trinitrotoluene metabolism http://purl.obolibrary.org/obo/GO_0018975 GO:0018974 biolink:BiologicalProcess 2,4,6-trinitrotoluene metabolic process The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives. go-plus.json TNT metabolism|2,4,6-trinitrotoluene metabolism|TNT metabolic process http://purl.obolibrary.org/obo/GO_0018974 GO:0018977 biolink:BiologicalProcess 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. UM-BBD_pathwayID:ddt go-plus.json DDT metabolic process|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism|DDT metabolism http://purl.obolibrary.org/obo/GO_0018977 GO:0018976 biolink:BiologicalProcess 1,2,3-tribromopropane metabolic process The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture. UM-BBD_pathwayID:tbp go-plus.json 1,2,3-tribromopropane metabolism http://purl.obolibrary.org/obo/GO_0018976 GO:0018971 biolink:BiologicalProcess anaerobic toluene metabolic process The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen. UM-BBD_pathwayID:tol2 go-plus.json anaerobic toluene metabolism http://purl.obolibrary.org/obo/GO_0018971 GO:0018970 biolink:BiologicalProcess toluene metabolic process The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications. go-plus.json methylbenzene metabolic process|toluene metabolism|methylbenzene metabolism http://purl.obolibrary.org/obo/GO_0018970 GO:0018973 biolink:BiologicalProcess trinitrotoluene metabolic process The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene. UM-BBD_pathwayID:tnt go-plus.json trinitrotoluene metabolism http://purl.obolibrary.org/obo/GO_0018973 GO:0018972 biolink:BiologicalProcess toluene-4-sulfonate metabolic process The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water. MetaCyc:TOLSULFDEG-PWY|UM-BBD_pathwayID:tsa go-plus.json 4-toluenesulfonate metabolism|toluene-4-sulphonate metabolism|4-methylbenzenesulfonate metabolism|4-methylbenzenesulfonate metabolic process|toluene-4-sulphonate metabolic process|toluene-4-sulfonate metabolism|4-toluenesulfonate metabolic process http://purl.obolibrary.org/obo/GO_0018972 PO:0025202 biolink:OntologyClass microsporangium A sporangium (PO:0025094) in which microspores (PO:0020048) are produced. go-plus.json microsporangia (exact, plural)|macrosporangia (related)|megasporangia (exact, plural)|小胞子嚢 (Japanese, exact)|macrosporangium (related)|microsporangio (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025202 PO:0025201 biolink:OntologyClass megasporangium A sporangium in which megaspores are produced. go-plus.json 大胞子嚢 (Japanese, exact)|megasporangio (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025201 GO:0004305 biolink:MolecularActivity ethanolamine kinase activity Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine. Reactome:R-HSA-1483222|KEGG_REACTION:R01468|RHEA:13069|MetaCyc:ETHANOLAMINE-KINASE-RXN|EC:2.7.1.82 go-plus.json ATP:ethanolamine O-phosphotransferase activity|ethanolamine phosphokinase activity|ethanolamine kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0004305 GO:0004304 biolink:MolecularActivity estrone sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate. MetaCyc:ESTRONE-SULFOTRANSFERASE-RXN|EC:2.8.2.4|RHEA:15973|Reactome:R-HSA-176664 go-plus.json oestrogen sulphotransferase activity|3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity|estrone sulphotransferase activity|estrogen sulphotransferase activity|estrogen sulfotransferase|3'-phosphoadenylylsulfate:oestrone sulfotransferase activity|3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0004304 GO:0004307 biolink:MolecularActivity ethanolaminephosphotransferase activity Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine. Reactome:R-HSA-1482962|RHEA:32943|EC:2.7.8.1|MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN go-plus.json phosphorylethanolamine-glyceride transferase activity|CDPethanolamine diglyceride phosphotransferase activity|EPT|CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity|diacylglycerol ethanolaminephosphotransferase activity http://purl.obolibrary.org/obo/GO_0004307 GO:0004306 biolink:MolecularActivity ethanolamine-phosphate cytidylyltransferase activity Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine. MetaCyc:2.7.7.14-RXN|EC:2.7.7.14|RHEA:24592|Reactome:R-HSA-1483190 go-plus.json CTP:phosphoethanolamine cytidylyltransferase activity|ethanolamine phosphate cytidylyltransferase activity|ET|phosphoethanolamine cytidylyltransferase activity|phosphorylethanolamine transferase activity|CTP-phosphoethanolamine cytidylyltransferase activity|CTP:ethanolamine-phosphate cytidylyltransferase activity http://purl.obolibrary.org/obo/GO_0004306 GO:0004301 biolink:MolecularActivity epoxide hydrolase activity Catalysis of the reaction: an epoxide + H2O = a glycol. Reactome:R-HSA-9026000|UM-BBD_enzymeID:e0397|Reactome:R-HSA-9026008|Reactome:R-HSA-9020257|Reactome:R-HSA-9018877|Reactome:R-HSA-9025998|EC:3.3.2.10|Reactome:R-HSA-9020258|Reactome:R-HSA-9018862|Reactome:R-HSA-2161961|RHEA:19037|Reactome:R-HSA-9020253|Reactome:R-HSA-9020252|Reactome:R-HSA-9024973|Reactome:R-HSA-9020270|Reactome:R-HSA-9024993|Reactome:R-HSA-9024890|MetaCyc:3.3.2.10-RXN go-plus.json aryl epoxide hydrase activity|soluble epoxide hydrolase activity|sEH|trans-stilbene oxide hydrolase activity|epoxide hydratase activity|arene-oxide hydratase activity|cytosolic epoxide hydrolase activity|epoxide hydrase activity http://purl.obolibrary.org/obo/GO_0004301 goslim_chembl GO:0004300 biolink:MolecularActivity enoyl-CoA hydratase activity Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O. UM-BBD_enzymeID:e0014|Reactome:R-HSA-70870|EC:4.2.1.17|Reactome:R-HSA-77325|Reactome:R-HSA-77333|Reactome:R-HSA-77344|MetaCyc:ENOYL-COA-HYDRAT-RXN|RHEA:16105|Reactome:R-HSA-77301|Reactome:R-HSA-77314|Reactome:R-HSA-77256|Reactome:R-HSA-70830|Reactome:R-HSA-77277 go-plus.json short-chain enoyl-CoA hydratase activity|D-3-hydroxyacyl-CoA dehydratase|acyl coenzyme A hydrase activity|2-octenoyl coenzyme A hydrase activity|enoyl hydrase activity|enol-CoA hydratase activity|(3S)-3-hydroxyacyl-CoA hydro-lyase activity|enoyl coenzyme A hydratase activity|short chain enoyl coenzyme A hydratase activity|crotonyl hydrase activity|enoyl coenzyme A hydrase (D)|enoyl coenzyme A hydrase (L)|unsaturated acyl-CoA hydratase activity|trans-2-enoyl-CoA hydratase activity|beta-hydroxyacid dehydrase activity|beta-hydroxyacyl-CoA dehydrase activity|ECH|hydratase, enoyl coenzyme A|2-enoyl-CoA hydratase activity http://purl.obolibrary.org/obo/GO_0004300 GO:0004303 biolink:MolecularActivity estradiol 17-beta-dehydrogenase activity Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+. Reactome:R-HSA-804969|Reactome:R-HSA-6810594|Reactome:R-HSA-8862137|EC:1.1.1.62|MetaCyc:ESTRADIOL-17-BETA-DEHYDROGENASE-RXN|Reactome:R-HSA-5693390|Reactome:R-HSA-5696822 go-plus.json 17beta-estradiol dehydrogenase activity|17-beta-estradiol dehydrogenase activity|17beta-hydroxysteroid dehydrogenase activity|17-beta-hydroxysteroid dehydrogenase activity|17beta,20alpha-hydroxysteroid dehydrogenase activity|estradiol 17beta-dehydrogenase activity|estrogen 17-oxidoreductase activity|estradiol-17beta:NAD(P)+ 17-oxidoreductase activity|estradiol dehydrogenase activity|17-beta-HSD activity|20alpha-hydroxysteroid dehydrogenase|17beta-HSD http://purl.obolibrary.org/obo/GO_0004303 GO:0004302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004302 GO:0018949 biolink:BiologicalProcess m-xylene metabolic process The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. UM-BBD_pathwayID:mxy go-plus.json meta-xylene metabolism|meta-xylene metabolic process|m-xylene metabolism http://purl.obolibrary.org/obo/GO_0018949 GO:0018946 biolink:BiologicalProcess aerobic organosilicon metabolic process The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen. UM-BBD_pathwayID:osi go-plus.json aerobic organosilicon metabolism|aerobic organosilicone metabolic process|aerobic organosilicone metabolism http://purl.obolibrary.org/obo/GO_0018946 GO:0018945 biolink:BiologicalProcess organosilicon metabolic process The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon. UM-BBD_pathwayID:osi go-plus.json organosilicon metabolism|organosilicone metabolic process|organosilicone metabolism http://purl.obolibrary.org/obo/GO_0018945 GO:0018948 biolink:BiologicalProcess xylene metabolic process The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. go-plus.json xylene metabolism http://purl.obolibrary.org/obo/GO_0018948 GO:0018947 biolink:BiologicalProcess anaerobic organosilicon metabolic process The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen. UM-BBD_pathwayID:osi go-plus.json anaerobic organosilicon metabolism|anaerobic organosilicone metabolic process|anaerobic organosilicone metabolism http://purl.obolibrary.org/obo/GO_0018947 GO:0018942 biolink:BiologicalProcess organometal metabolic process The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms. go-plus.json organometal metabolism http://purl.obolibrary.org/obo/GO_0018942 goslim_pir GO:0018941 biolink:BiologicalProcess organomercury metabolic process The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom. UM-BBD_pathwayID:ogm go-plus.json organomercury metabolism http://purl.obolibrary.org/obo/GO_0018941 GO:0018944 biolink:BiologicalProcess tri-n-butyltin metabolic process The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms. UM-BBD_pathwayID:tbt go-plus.json tri-n-butyltin metabolism http://purl.obolibrary.org/obo/GO_0018944 GO:0018943 biolink:BiologicalProcess organotin metabolic process The chemical reactions and pathways involving organotin, an organic compound containing a tin atom. go-plus.json organotin metabolism http://purl.obolibrary.org/obo/GO_0018943 GO:0018940 biolink:BiologicalProcess orcinol metabolic process The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants. UM-BBD_pathwayID:orc|MetaCyc:P342-PWY go-plus.json orcin metabolic process|orcinol metabolism|orcin metabolism http://purl.obolibrary.org/obo/GO_0018940 GO:0004309 biolink:MolecularActivity exopolyphosphatase activity Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate. RHEA:21528|MetaCyc:EXOPOLYPHOSPHATASE-RXN|EC:3.6.1.11 go-plus.json acid phosphoanhydride phosphohydrolase activity|Gra-Pase activity|polyphosphate phosphohydrolase activity|exopolypase activity|metaphosphatase activity http://purl.obolibrary.org/obo/GO_0004309 GO:0004308 biolink:MolecularActivity exo-alpha-sialidase activity Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. Reactome:R-HSA-9638120|Reactome:R-HSA-1605723|EC:3.2.1.18|Reactome:R-HSA-1605724|Reactome:R-HSA-168870|Reactome:R-HSA-1605768|Reactome:R-HSA-4084999|Reactome:R-HSA-4341669|MetaCyc:3.2.1.18-RXN|Reactome:R-HSA-4085029|Reactome:R-HSA-4084994 go-plus.json alpha-neuraminidase activity|acetylneuraminidase activity|neuraminidase activity|acetylneuraminyl hydrolase activity|sialidase activity|N-acylneuraminate glycohydrolase activity http://purl.obolibrary.org/obo/GO_0004308 GO:0004316 biolink:MolecularActivity 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+. MetaCyc:3-OXOACYL-ACP-REDUCT-RXN|EC:1.1.1.100|MetaCyc:RXN-10659|MetaCyc:RXN-11476|MetaCyc:RXN-11480|Reactome:R-HSA-8862152|RHEA:17397 go-plus.json beta-ketoacyl-acyl carrier protein reductase activity|3-oxoacyl-[acyl-carrier protein] reductase activity|beta-ketoacyl-acyl-carrier protein(ACP) reductase activity|3-oxoacyl-ACPreductase activity|beta-ketoacyl thioester reductase activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity|3-oxoacyl-acyl-carrier-protein reductase activity|beta-ketoacyl reductase activity|beta-ketoacyl-ACP reductase activity|beta-ketoacyl acyl carrier protein (ACP) reductase activity|3-ketoacyl acyl carrier protein reductase activity|NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity|3-oxoacyl-ACP reductase activity http://purl.obolibrary.org/obo/GO_0004316 GO:0004315 biolink:MolecularActivity 3-oxoacyl-[acyl-carrier-protein] synthase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]. MetaCyc:2.3.1.179-RXN|EC:2.3.1.179|MetaCyc:3-OXOACYL-ACP-SYNTH-RXN|EC:2.3.1.41|RHEA:22836 go-plus.json beta-ketoacyl-acyl carrier protein synthase activity|beta-ketoacyl synthetase activity|fatty acid condensing enzyme activity|condensing enzyme activity|3-oxoacyl-[acyl-carrier protein] synthase activity|ketoacyl-ACP synthase activity|beta-ketoacyl-ACP synthase I activity|beta-ketoacyl acyl carrier protein synthase activity|3-oxoacyl-acyl carrier protein synthase I activity|beta-ketoacyl-acyl carrier protein synthetase activity|acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)|3-oxoacyl-ACP synthase activity|3-oxoacyl-acyl-carrier-protein synthase activity|acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity|acyl-malonyl acyl carrier protein-condensing enzyme activity|KAS II|KASI|3-oxoacyl:ACP synthase I|KAS I activity|beta-ketoacyl-ACP synthase II activity|KASII|3-ketoacyl-acyl carrier protein synthase activity|beta-ketoacylsynthase activity|beta-ketoacyl-[acyl carrier protein] synthase activity|beta-ketoacyl-acyl-carrier-protein synthase II activity|beta-ketoacyl-ACP synthetase activity|beta-ketoacyl-acyl-carrier-protein synthase I http://purl.obolibrary.org/obo/GO_0004315 CHEBI:77208 biolink:ChemicalSubstance hexadecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77208 GO:0004318 biolink:MolecularActivity enoyl-[acyl-carrier-protein] reductase (NADH) activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+. EC:1.3.1.9|MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN go-plus.json NADH-enoyl acyl carrier protein reductase activity|enoyl-acyl-carrier-protein reductase (NADH)|enoyl-ACP reductase (NADH) activity|enoyl-[acyl-carrier protein] reductase (NADH) activity|NADH-specific enoyl-ACP reductase activity|acyl-acyl-carrier-protein:NAD+ oxidoreductase http://purl.obolibrary.org/obo/GO_0004318 CHEBI:77207 biolink:ChemicalSubstance tetradecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77207 CHEBI:77206 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77206 chebi_ph7_3 GO:0004317 biolink:MolecularActivity 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O. KEGG_REACTION:R04462|RHEA:41908|MetaCyc:4.2.1.61-RXN|EC:4.2.1.59 go-plus.json beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity|D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity|3-hydroxypalmitoyl-ACP dehydratase activity|(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity|beta-hydroxypalmitoyl thioester dehydratase activity|D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)|3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|beta-hydroxypalmityl-ACP dehydrase activity|3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity http://purl.obolibrary.org/obo/GO_0004317 GO:0004312 biolink:MolecularActivity fatty acid synthase activity Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+. Reactome:R-HSA-75872|RHEA:14993|MetaCyc:FATTY-ACID-SYNTHASE-RXN|EC:2.3.1.85 go-plus.json fatty-acid synthase activity|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) http://purl.obolibrary.org/obo/GO_0004312 GO:0004311 biolink:MolecularActivity farnesyltranstransferase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate. RHEA:17653|MetaCyc:FARNESYLTRANSTRANSFERASE-RXN|KEGG_REACTION:R02061|EC:2.5.1.29 go-plus.json geranylgeranyl-PP synthetase activity|trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|geranylgeranyl pyrophosphate synthase activity|geranylgeranyl-diphosphate synthase activity|geranylgeranyl pyrophosphate synthetase activity|farnesyltransferase activity http://purl.obolibrary.org/obo/GO_0004311 CHEBI:53259 biolink:ChemicalSubstance poly(ethylene terephthalate) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53259 chebi_ph7_3 GO:0004314 biolink:MolecularActivity [acyl-carrier-protein] S-malonyltransferase activity Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein]. MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN|Reactome:R-HSA-8933547|EC:2.3.1.39 go-plus.json malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity|malonyl coenzyme A-acyl carrier protein transacylase activity|malonyl-CoA:acyl carrier protein transacylase activity|ACP S-malonyltransferase activity|acyl-carrier-protein S-malonyltransferase activity|MCAT activity|malonyl-CoA-acyl carrier protein transacylase activity|acyl carrier protein malonyltransferase activity|acyl carrier proteinmalonyltransferase activity|malonyl-CoA:AcpM transacylase activity|MAT|[acyl-carrier protein] S-malonyltransferase activity|malonyl-CoA:ACP transacylase activity|malonyl transacylase activity|FabD|malonyl transferase activity http://purl.obolibrary.org/obo/GO_0004314 GO:0004313 biolink:MolecularActivity [acyl-carrier-protein] S-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein]. MetaCyc:ACP-S-ACETYLTRANSFER-RXN|EC:2.3.1.38|RHEA:41788 go-plus.json acyl-carrier-protein acetyltransferase activity|ACAT activity|acetyl coenzyme A-acyl-carrier-protein transacylase activity|acyl-carrier-protein S-acetyltransferase activity|[acyl-carrier protein] S-acetyltransferase activity|acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity|acyl-carrier-proteinacetyltransferase activity|ACP S-acetyltransferase activity|ACP acetyltransferase activity|ACPacetyltransferase activity http://purl.obolibrary.org/obo/GO_0004313 GO:0004310 biolink:MolecularActivity farnesyl-diphosphate farnesyltransferase activity Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate. Reactome:R-HSA-191402|Reactome:R-HSA-191405|MetaCyc:2.5.1.21-RXN|EC:2.5.1.21 go-plus.json farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity|presqualene-diphosphate synthase activity|presqualene synthase activity http://purl.obolibrary.org/obo/GO_0004310 GO:0102900 biolink:MolecularActivity dehydroabietadienal hydroxylase activity Catalysis of the reaction: dehydroabietadienal + NADPH + O2 <=> dehydroabietic acid + NADP + H2O. MetaCyc:RXN-8534 go-plus.json http://purl.obolibrary.org/obo/GO_0102900 GO:0102902 biolink:MolecularActivity isopimaradienal hydroxylase activity Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O. MetaCyc:RXN-8538 go-plus.json http://purl.obolibrary.org/obo/GO_0102902 GO:0018957 biolink:BiologicalProcess phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite. UM-BBD_pathwayID:pha2 go-plus.json phenanthrene breakdown via trans-9(S),10(S)-dihydrodiolphenanthrene|phenanthrene degradation via trans-9(S),10(S)-dihydrodiolphenanthrene http://purl.obolibrary.org/obo/GO_0018957 GO:0102901 biolink:MolecularActivity isopimaradienol hydroxylase activity Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 <=> isopimaradiene-diol + NADP + H2O. MetaCyc:RXN-8536 go-plus.json http://purl.obolibrary.org/obo/GO_0102901 GO:0018956 biolink:BiologicalProcess phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite. UM-BBD_pathwayID:pha3 go-plus.json phenanthrene breakdown via trans-9(R),10(R)-dihydrodiolphenanthrene|phenanthrene degradation via trans-9(R),10(R)-dihydrodiolphenanthrene http://purl.obolibrary.org/obo/GO_0018956 GO:0018959 biolink:BiologicalProcess aerobic phenol-containing compound metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. UM-BBD_pathwayID:pba go-plus.json aerobic phenol-containing compound metabolism http://purl.obolibrary.org/obo/GO_0018959 GO:0102904 biolink:MolecularActivity germacrene C synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid. MetaCyc:RXN-8561|RHEA:28302|EC:4.2.3.60 go-plus.json http://purl.obolibrary.org/obo/GO_0102904 GO:0102903 biolink:MolecularActivity gamma-terpinene synthase activity Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid. RHEA:32559|EC:4.2.3.114|MetaCyc:RXN-8547 go-plus.json http://purl.obolibrary.org/obo/GO_0102903 GO:0018958 biolink:BiologicalProcess phenol-containing compound metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. UM-BBD_pathwayID:phe go-plus.json carbolic acid metabolic process|phenol-containing compound metabolism|carbolic acid metabolism|hydroxybenzene metabolism|hydroxybenzene metabolic process http://purl.obolibrary.org/obo/GO_0018958 GO:0018953 biolink:BiologicalProcess p-cymene metabolic process The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants. UM-BBD_pathwayID:pcy go-plus.json p-cymene metabolism http://purl.obolibrary.org/obo/GO_0018953 GO:0102906 biolink:MolecularActivity 7-epi-alpha-selinene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (-)-7-epi-alpha-selinene + diphosphoric acid. EC:4.2.3.86|RHEA:30383|MetaCyc:RXN-8609 go-plus.json http://purl.obolibrary.org/obo/GO_0102906 GO:0018952 biolink:BiologicalProcess parathion metabolic process The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition. UM-BBD_pathwayID:pthn go-plus.json parathion metabolism http://purl.obolibrary.org/obo/GO_0018952 GO:0102905 biolink:MolecularActivity valencene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (+)-valencene + diphosphoric acid. EC:4.2.3.73|RHEA:29511|MetaCyc:RXN-8608 go-plus.json http://purl.obolibrary.org/obo/GO_0102905 GO:0018955 biolink:BiologicalProcess phenanthrene metabolic process The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish. UM-BBD_pathwayID:pha go-plus.json phenanthrene metabolism http://purl.obolibrary.org/obo/GO_0018955 GO:0102908 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102908 GO:0102907 biolink:MolecularActivity sesquisabinene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene. MetaCyc:RXN-8622 go-plus.json http://purl.obolibrary.org/obo/GO_0102907 GO:0018954 biolink:BiologicalProcess pentaerythritol tetranitrate metabolic process The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator. UM-BBD_pathwayID:petn go-plus.json pentaerythritol tetranitrate metabolism http://purl.obolibrary.org/obo/GO_0018954 CHEBI:77201 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77201 chebi_ph7_3 GO:0102909 biolink:MolecularActivity alpha-ketoglutarate reductase activity (NADH-dependent) Catalysis of the reaction: NAD + 2-hydroxyglutarate = H+ + 2-oxoglutarate + NADH. MetaCyc:RXN-8645 go-plus.json http://purl.obolibrary.org/obo/GO_0102909 CHEBI:77200 biolink:ChemicalSubstance (10E,12Z)-octadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77200 chebi_ph7_3 GO:0018951 biolink:BiologicalProcess p-xylene metabolic process The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. UM-BBD_pathwayID:pxy go-plus.json p-xylene metabolism|para-xylene metabolism|para-xylene metabolic process http://purl.obolibrary.org/obo/GO_0018951 GO:0018950 biolink:BiologicalProcess o-xylene metabolic process The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. UM-BBD_pathwayID:oxy go-plus.json o-xylene metabolism|ortho-xylene metabolic process|ortho-xylene metabolism http://purl.obolibrary.org/obo/GO_0018950 CHEBI:77205 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77205 chebi_ph7_3 GO:0004319 biolink:MolecularActivity enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+. MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN|EC:1.3.1.10 go-plus.json acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)|NADPH 2-enoyl Co A reductase activity|enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity|enoyl-ACP reductase (NADPH, B-specific) activity|enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)|enoyl-acyl-carrier-protein reductase (NADPH, B-specific)|reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)|enoyl acyl-carrier-protein reductase activity http://purl.obolibrary.org/obo/GO_0004319 CHEBI:77203 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77203 chebi_ph7_3 CHEBI:77202 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77202 chebi_ph7_3 GO:0102751 biolink:MolecularActivity UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+. RHEA:56560|EC:2.4.1.186|MetaCyc:RXN-7667 go-plus.json http://purl.obolibrary.org/obo/GO_0102751 GO:0102750 biolink:MolecularActivity tetrahydrogeranylgeranyl-chlorophyll a reductase activity Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+. MetaCyc:RXN-7666 go-plus.json http://purl.obolibrary.org/obo/GO_0102750 GO:0102753 biolink:MolecularActivity chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid. MetaCyc:RXN-7673 go-plus.json http://purl.obolibrary.org/obo/GO_0102753 GO:0102752 biolink:MolecularActivity 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) Catalysis of the reaction: a glucosylated glycogenin = a glycogen. MetaCyc:RXN-7669|EC:2.4.1.18 go-plus.json http://purl.obolibrary.org/obo/GO_0102752 GO:0102755 biolink:MolecularActivity gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide. MetaCyc:RXN-7680 go-plus.json http://purl.obolibrary.org/obo/GO_0102755 GO:0102754 biolink:MolecularActivity chlorophyllide-b:phytyl-diphosphate phytyltransferase activity Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid. MetaCyc:RXN-7674 go-plus.json http://purl.obolibrary.org/obo/GO_0102754 GO:0102757 biolink:MolecularActivity NADPH phosphatase activity Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate. MetaCyc:RXN-7703|RHEA:60664 go-plus.json http://purl.obolibrary.org/obo/GO_0102757 GO:0102756 biolink:MolecularActivity very-long-chain 3-ketoacyl-CoA synthase activity Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA. EC:2.3.1.199|RHEA:32727|MetaCyc:RXN-7697 go-plus.json http://purl.obolibrary.org/obo/GO_0102756 GO:0102759 biolink:MolecularActivity campestanol hydroxylase activity Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP. MetaCyc:RXN-773 go-plus.json http://purl.obolibrary.org/obo/GO_0102759 GO:0102758 biolink:MolecularActivity very-long-chain enoyl-CoA reductase activity Catalysis of the reaction: NADP(3-) + a very-long-chain 2,3,4-saturated fatty acyl CoA <=> NADPH(4-) + H+ + a very-long-chain trans-2,3-dehydroacyl-CoA. EC:1.3.1.93|RHEA:14473|MetaCyc:RXN-7711 go-plus.json http://purl.obolibrary.org/obo/GO_0102758 GO:0102760 biolink:MolecularActivity 6-deoxocathasterone hydroxylase activity Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor. MetaCyc:RXN-774 go-plus.json http://purl.obolibrary.org/obo/GO_0102760 GO:0102762 biolink:MolecularActivity eriodictyol 4'-O-methyltransferase activity Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine. MetaCyc:RXN-7754 go-plus.json http://purl.obolibrary.org/obo/GO_0102762 GO:0102761 biolink:MolecularActivity eriodictyol 3'-O-methyltransferase activity Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine. RHEA:60948|MetaCyc:RXN-7753 go-plus.json http://purl.obolibrary.org/obo/GO_0102761 GO:0102764 biolink:MolecularActivity 6-deoxotyphasterol C-23 hydroxylase activity Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor. MetaCyc:RXN-777 go-plus.json http://purl.obolibrary.org/obo/GO_0102764 GO:0102763 biolink:MolecularActivity phytyl-P kinase activity Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate. MetaCyc:RXN-7763|RHEA:38099 go-plus.json http://purl.obolibrary.org/obo/GO_0102763 GO:0102766 biolink:MolecularActivity naringenin 7-O-methyltransferase activity Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine <=> sakuranetin + S-adenosyl-L-homocysteine + H+. RHEA:31539|MetaCyc:RXN-7773|EC:2.1.1.232 go-plus.json http://purl.obolibrary.org/obo/GO_0102766 GO:0102765 biolink:MolecularActivity UDP-D-apiose synthase activity Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide. MetaCyc:RXN-7770 go-plus.json http://purl.obolibrary.org/obo/GO_0102765 GO:0102768 biolink:MolecularActivity anthocyanidin synthase activity Catalysis of the reaction: flavan-3,3',4,4',5,5',7-heptol + O2 + 2-oxoglutarate = H+ + delphinidin + 2 H2O + carbon dioxide + succinate. MetaCyc:RXN-7785 go-plus.json http://purl.obolibrary.org/obo/GO_0102768 GO:0102767 biolink:MolecularActivity flavanone 4'-O-methyltransferase activity Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine. EC:2.1.1.231|MetaCyc:RXN-7777|RHEA:31743 go-plus.json http://purl.obolibrary.org/obo/GO_0102767 GO:0102769 biolink:MolecularActivity dihydroceramide glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine. MetaCyc:RXN-7793|EC:2.4.1.80 go-plus.json http://purl.obolibrary.org/obo/GO_0102769 CHEBI:7872 biolink:ChemicalSubstance oxytocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_7872 GO:0102771 biolink:MolecularActivity sphingolipid very long chain fatty acid alpha-hydroxylase activity Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide. MetaCyc:RXN-7796|RHEA:46512 go-plus.json http://purl.obolibrary.org/obo/GO_0102771 GO:0102770 biolink:MolecularActivity inositol phosphorylceramide synthase activity Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol. MetaCyc:RXN-7795 go-plus.json http://purl.obolibrary.org/obo/GO_0102770 GO:0102773 biolink:MolecularActivity dihydroceramide kinase activity Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate. EC:2.7.1.138|MetaCyc:RXN-7799 go-plus.json http://purl.obolibrary.org/obo/GO_0102773 GO:0102772 biolink:MolecularActivity sphingolipid long-chain base 4-hydroxylase activity Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P). MetaCyc:RXN-7797 go-plus.json http://purl.obolibrary.org/obo/GO_0102772 GO:0102775 biolink:MolecularActivity 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide. MetaCyc:RXN-7826 go-plus.json http://purl.obolibrary.org/obo/GO_0102775 GO:0102774 biolink:MolecularActivity p-coumaroyltriacetic acid lactone synthase activity Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide. MetaCyc:RXN-7822 go-plus.json http://purl.obolibrary.org/obo/GO_0102774 GO:0102777 biolink:MolecularActivity caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-). EC:2.3.1.153|MetaCyc:RXN-7842 go-plus.json http://purl.obolibrary.org/obo/GO_0102777 GO:0102776 biolink:MolecularActivity UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+. MetaCyc:RXN-7828 go-plus.json http://purl.obolibrary.org/obo/GO_0102776 GO:0102779 biolink:MolecularActivity cannabidiolate synthase activity Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide. RHEA:34411|EC:1.21.3.8|MetaCyc:RXN-7855 go-plus.json http://purl.obolibrary.org/obo/GO_0102779 GO:0102778 biolink:MolecularActivity Delta9-tetrahydrocannabinolate synthase activity Catalysis of the reaction: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide. RHEA:34135|EC:1.21.3.7|MetaCyc:RXN-7854 go-plus.json http://purl.obolibrary.org/obo/GO_0102778 GO:0102780 biolink:MolecularActivity sitosterol hydroxylase activity Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP. MetaCyc:RXN-7876 go-plus.json http://purl.obolibrary.org/obo/GO_0102780 GO:0102782 biolink:MolecularActivity cholestanol hydroxylase activity Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP. MetaCyc:RXN-7878 go-plus.json http://purl.obolibrary.org/obo/GO_0102782 GO:0102781 biolink:MolecularActivity isofucosterol hydroxylase activity Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP. MetaCyc:RXN-7877 go-plus.json http://purl.obolibrary.org/obo/GO_0102781 GO:0102784 biolink:MolecularActivity lutein oxygenase activity Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. MetaCyc:RXN-7884 go-plus.json http://purl.obolibrary.org/obo/GO_0102784 GO:0102783 biolink:MolecularActivity beta-carotene oxygenase activity Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. MetaCyc:RXN-7883 go-plus.json http://purl.obolibrary.org/obo/GO_0102783 GO:0102786 biolink:MolecularActivity stearoyl-[acp] desaturase activity Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin. RHEA:11776|EC:1.14.19.2|MetaCyc:RXN-7903 go-plus.json http://purl.obolibrary.org/obo/GO_0102786 GO:0102785 biolink:MolecularActivity violaxanthin oxygenase activity Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. MetaCyc:RXN-7886 go-plus.json http://purl.obolibrary.org/obo/GO_0102785 GO:0102788 biolink:MolecularActivity 4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A. MetaCyc:RXN-7998 go-plus.json http://purl.obolibrary.org/obo/GO_0102788 GO:0102787 biolink:MolecularActivity caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A. MetaCyc:RXN-7997 go-plus.json http://purl.obolibrary.org/obo/GO_0102787 GO:0102789 biolink:MolecularActivity UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP. MetaCyc:RXN-8005 go-plus.json http://purl.obolibrary.org/obo/GO_0102789 NCBITaxon:243090 biolink:OrganismalEntity Rhodopirellula baltica SH 1 go-plus.json Rhodopirellula baltica strain SH 1|Rhodopirellula baltica str. SH 1|Pirellula sp. 1 http://purl.obolibrary.org/obo/NCBITaxon_243090 GO:0102711 biolink:MolecularActivity gibberellin A25,oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide. MetaCyc:RXN-6541 go-plus.json http://purl.obolibrary.org/obo/GO_0102711 GO:0102710 biolink:MolecularActivity D-inositol-3-phosphate glycosyltransferase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+. RHEA:26188|EC:2.4.1.250|MetaCyc:RXN-6501 go-plus.json http://purl.obolibrary.org/obo/GO_0102710 GO:0102713 biolink:MolecularActivity gibberellin A25 hydroxylase activity Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide. MetaCyc:RXN-6543 go-plus.json http://purl.obolibrary.org/obo/GO_0102713 GO:0102712 biolink:MolecularActivity gibberellin A13,oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide. MetaCyc:RXN-6542 go-plus.json http://purl.obolibrary.org/obo/GO_0102712 GO:0102715 biolink:MolecularActivity gibberellin A17,oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide. MetaCyc:RXN-6546 go-plus.json http://purl.obolibrary.org/obo/GO_0102715 GO:0102714 biolink:MolecularActivity gibberellin A12,oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide. MetaCyc:RXN-6544 go-plus.json http://purl.obolibrary.org/obo/GO_0102714 GO:0102717 biolink:MolecularActivity DIBOA-glucoside oxygenase activity Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide. MetaCyc:RXN-6685|RHEA:32115|EC:1.14.11.59 go-plus.json http://purl.obolibrary.org/obo/GO_0102717 GO:0102716 biolink:MolecularActivity gibberellin A28,oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide. MetaCyc:RXN-6547 go-plus.json http://purl.obolibrary.org/obo/GO_0102716 GO:0102719 biolink:MolecularActivity S-adenosyl-L-methionine:eugenol-O-methyltransferase activity Catalysis of the reaction: eugenol + S-adenosyl-L-methionine = H+ + O-methyleugenol + S-adenosyl-L-homocysteine. MetaCyc:RXN-6741|EC:2.1.1.146 go-plus.json http://purl.obolibrary.org/obo/GO_0102719 GO:0102718 biolink:MolecularActivity TRIBOA-glucoside methyltransferase activity Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-6687|RHEA:32099|EC:2.1.1.241 go-plus.json http://purl.obolibrary.org/obo/GO_0102718 GO:0102720 biolink:MolecularActivity acetyl-coenzyme A:acetyl alcohol acetyltransferase activity Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A. MetaCyc:RXN-6762|RHEA:36147|EC:2.3.1.224 go-plus.json http://purl.obolibrary.org/obo/GO_0102720 GO:0102722 biolink:MolecularActivity gamma-hydroxybutyrate dehydrogenase activity (NAD(P)-dependent Catalysis of the reaction: 4-hydroxybutyrate + NAD(P) = 4-oxobutanoate + H+ + NAD(P)H. MetaCyc:RXN-6903 go-plus.json http://purl.obolibrary.org/obo/GO_0102722 GO:0102721 biolink:MolecularActivity ubiquinol:oxygen oxidoreductase activity Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone. MetaCyc:RXN-6883|EC:1.10.3.11|RHEA:30255 go-plus.json http://purl.obolibrary.org/obo/GO_0102721 GO:0102724 biolink:MolecularActivity UDP-glucose:curcumin monoglucoside glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP. MetaCyc:RXN-7063 go-plus.json http://purl.obolibrary.org/obo/GO_0102724 GO:0102723 biolink:MolecularActivity UDP-glucose:curcumin glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+. MetaCyc:RXN-7062 go-plus.json http://purl.obolibrary.org/obo/GO_0102723 GO:0102726 biolink:MolecularActivity DIMBOA glucoside beta-D-glucosidase activity Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose. EC:3.2.1.182|RHEA:33975|MetaCyc:RXN-7082 go-plus.json http://purl.obolibrary.org/obo/GO_0102726 GO:0102725 biolink:MolecularActivity 24-methyldesmosterol reductase activity Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP. MetaCyc:RXN-708 go-plus.json http://purl.obolibrary.org/obo/GO_0102725 GO:0102728 biolink:MolecularActivity campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH. MetaCyc:RXN-711|RHEA:54416 go-plus.json http://purl.obolibrary.org/obo/GO_0102728 GO:0102727 biolink:MolecularActivity 3beta-hydroxysteroid dehydrogenase activity Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+. MetaCyc:RXN-710 go-plus.json http://purl.obolibrary.org/obo/GO_0102727 GO:0102729 biolink:MolecularActivity 6-oxocampestanol hydroxylase activity Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP. MetaCyc:RXN-715 go-plus.json http://purl.obolibrary.org/obo/GO_0102729 GO:0102731 biolink:MolecularActivity D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP. MetaCyc:RXN-7185 go-plus.json http://purl.obolibrary.org/obo/GO_0102731 GO:0102730 biolink:MolecularActivity cathasterone hydroxylase activity Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor. MetaCyc:RXN-716 go-plus.json http://purl.obolibrary.org/obo/GO_0102730 GO:0102733 biolink:MolecularActivity typhasterol C-23 hydroxylase activity Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor. MetaCyc:RXN-719 go-plus.json http://purl.obolibrary.org/obo/GO_0102733 GO:0102732 biolink:MolecularActivity myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP. MetaCyc:RXN-7186|EC:2.7.1.140 go-plus.json http://purl.obolibrary.org/obo/GO_0102732 GO:0102735 biolink:MolecularActivity trihydroxybenzophenone synthase activity Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide. MetaCyc:RXN-7481|RHEA:35143|EC:2.3.1.220 go-plus.json http://purl.obolibrary.org/obo/GO_0102735 GO:0102734 biolink:MolecularActivity brassinolide synthase activity Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O. MetaCyc:RXN-720 go-plus.json http://purl.obolibrary.org/obo/GO_0102734 GO:0102737 biolink:MolecularActivity p-coumaroyltriacetic acid synthase activity Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate. MetaCyc:RXN-7577 go-plus.json http://purl.obolibrary.org/obo/GO_0102737 GO:0102739 biolink:MolecularActivity (gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide. MetaCyc:RXN-7591 go-plus.json http://purl.obolibrary.org/obo/GO_0102739 GO:0102738 biolink:MolecularActivity (gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate. MetaCyc:RXN-7589 go-plus.json http://purl.obolibrary.org/obo/GO_0102738 GO:0102740 biolink:MolecularActivity theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine. EC:2.1.1.160|MetaCyc:RXN-7599|RHEA:20944 go-plus.json http://purl.obolibrary.org/obo/GO_0102740 GO:0102742 biolink:MolecularActivity R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP. MetaCyc:RXN-7632|EC:1.1.1.237 go-plus.json http://purl.obolibrary.org/obo/GO_0102742 GO:0102741 biolink:MolecularActivity paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine. EC:2.1.1.160|MetaCyc:RXN-7601|RHEA:10280 go-plus.json http://purl.obolibrary.org/obo/GO_0102741 GO:0102744 biolink:MolecularActivity all-trans-geranyl-geranyl diphosphate reductase activity Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP. MetaCyc:RXN-7658 go-plus.json http://purl.obolibrary.org/obo/GO_0102744 GO:0102743 biolink:MolecularActivity eriodictyol,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O. MetaCyc:RXN-7653 go-plus.json http://purl.obolibrary.org/obo/GO_0102743 GO:0102746 biolink:MolecularActivity tetrahydrogeranylgeranyl-PP reductase activity Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP. MetaCyc:RXN-7660 go-plus.json http://purl.obolibrary.org/obo/GO_0102746 GO:0102745 biolink:MolecularActivity dihydrogeranylgeranyl-PP reductase activity Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP. MetaCyc:RXN-7659 go-plus.json http://purl.obolibrary.org/obo/GO_0102745 GO:0102748 biolink:MolecularActivity geranylgeranyl-chlorophyll a reductase activity Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP. MetaCyc:RXN-7664 go-plus.json http://purl.obolibrary.org/obo/GO_0102748 GO:0102747 biolink:MolecularActivity chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid. MetaCyc:RXN-7663 go-plus.json http://purl.obolibrary.org/obo/GO_0102747 GO:0102749 biolink:MolecularActivity dihydrogeranylgeranyl-chlorophyll a reductase activity Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP. MetaCyc:RXN-7665 go-plus.json http://purl.obolibrary.org/obo/GO_0102749 CHEBI:7896 biolink:ChemicalSubstance hexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_7896 chebi_ph7_3 CHEBI:28209 biolink:ChemicalSubstance 5(S)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_28209 CHEBI:28205 biolink:ChemicalSubstance phaseic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28205 CHEBI:28207 biolink:ChemicalSubstance D-galactosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28207 CHEBI:28206 biolink:ChemicalSubstance 2'-hydroxyisoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_28206 chebi_ph7_3 CHEBI:28201 biolink:ChemicalSubstance rotenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28201 chebi_ph7_3 CHEBI:28200 biolink:ChemicalSubstance 2-chloroethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28200 chebi_ph7_3 CHEBI:28203 biolink:ChemicalSubstance N-acetyl-D-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28203 UBERON:0006289 biolink:AnatomicalEntity rib pre-cartilage condensation A rib endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006289 UBERON:0006288 biolink:AnatomicalEntity rib cartilage element A rib endochondral element that is composed primarily of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006288 CHEBI:77170 biolink:ChemicalSubstance (2E)-tetradecenedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77170 CHEBI:100 biolink:ChemicalSubstance (-)-medicarpin go-plus.json http://purl.obolibrary.org/obo/CHEBI_100 chebi_ph7_3 UBERON:0006284 biolink:AnatomicalEntity early prosencephalic vesicle future brain vesicle that gives rise to telencephalic ventricle/lateral ventricles and 3rd ventricle go-plus.json prosencephalic ventricle|forebrain vesicle|preevaginated forebrain vesicle|prosencephalic vesicle|forebrain ventricle http://purl.obolibrary.org/obo/UBERON_0006284 UBERON:0006283 biolink:AnatomicalEntity future cardiac ventricle Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle. go-plus.json early heart ventricle|future heart ventricle|primitive ventricle|embryonic heart ventricle|primordial ventricle|presumptive cardiac ventricle heart tube|primitive ventricle of heart|primordial cardiac ventricle|embryonic ventricle http://purl.obolibrary.org/obo/UBERON_0006283 CHEBI:77172 biolink:ChemicalSubstance 3-oxotetradecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77172 CHEBI:77179 biolink:ChemicalSubstance 4-O-methylrhodomycin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_77179 CHEBI:77178 biolink:ChemicalSubstance histological dye go-plus.json http://purl.obolibrary.org/obo/CHEBI_77178 CHEBI:28217 biolink:ChemicalSubstance acrylonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_28217 chebi_ph7_3 CHEBI:28211 biolink:ChemicalSubstance gibberellin A44 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28211 CHEBI:119 biolink:ChemicalSubstance D-synephrine go-plus.json http://purl.obolibrary.org/obo/CHEBI_119 CHEBI:28214 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-glutaminyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28214 CHEBI:77182 biolink:ChemicalSubstance food colouring go-plus.json http://purl.obolibrary.org/obo/CHEBI_77182 CHEBI:77181 biolink:ChemicalSubstance crystal violet cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_77181 chebi_ph7_3 UBERON:0006274 biolink:AnatomicalEntity tetrapod parietal bone primordium go-plus.json parietal bone primordium http://purl.obolibrary.org/obo/UBERON_0006274 CHEBI:77186 biolink:ChemicalSubstance 1-palmityl-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77186 chebi_ph7_3 CHEBI:77185 biolink:ChemicalSubstance 1-palmityl-2-oleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77185 chebi_ph7_3 UBERON:0006273 biolink:AnatomicalEntity otic pit the pair of depressions of thickened otic placode epithelium, that further develops into the otic vesicles go-plus.json otic cup http://purl.obolibrary.org/obo/UBERON_0006273 CHEBI:77184 biolink:ChemicalSubstance 1-palmityl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77184 chebi_ph7_3 UBERON:0006271 biolink:AnatomicalEntity orbital fissure Either of two openings transmitting nerves and blood vessels to or from the orbit. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006271 CHEBI:77183 biolink:ChemicalSubstance (2E)-hexadecenedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77183 CHEBI:77189 biolink:ChemicalSubstance (3R)-hydroxyhexadecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77189 CHEBI:77187 biolink:ChemicalSubstance 1-palmityl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77187 chebi_ph7_3 UBERON:0006279 biolink:AnatomicalEntity pleuroperitoneal canal Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity. go-plus.json pleuroperitoneal channel http://purl.obolibrary.org/obo/UBERON_0006279 CHEBI:129 biolink:ChemicalSubstance (-)-beta-phellandrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_129 chebi_ph7_3 UBERON:0006267 biolink:AnatomicalEntity notochordal plate The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006267 CHEBI:122 biolink:ChemicalSubstance (-)-usnic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_122 CHEBI:77191 biolink:ChemicalSubstance 3-oxohexadecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77191 CHEBI:77190 biolink:ChemicalSubstance CDP-dipalmitoyl-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77190 chebi_ph7_3 UBERON:0006264 biolink:AnatomicalEntity mouth-foregut junction An anatomical junctions that overlaps the mouth and foregut. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006264 CHEBI:128 biolink:ChemicalSubstance (S)-(-)-alpha-terpineol go-plus.json http://purl.obolibrary.org/obo/CHEBI_128 chebi_ph7_3 CHEBI:77195 biolink:ChemicalSubstance 10-carboxy-13-deoxydaunorubicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77195 UBERON:0006261 biolink:AnatomicalEntity male genital tubercle A differentiated genital tubercle that is part of a male reproductive system. go-plus.json genital tubercle of male|penis anlage http://purl.obolibrary.org/obo/UBERON_0006261 UBERON:0006260 biolink:AnatomicalEntity lingual swellings go-plus.json lingual swelling http://purl.obolibrary.org/obo/UBERON_0006260 CHEBI:77194 biolink:ChemicalSubstance EC 2.7.1.33 (pantothenate kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77194 CHEBI:77199 biolink:ChemicalSubstance (3S)-hydroxyhexadecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77199 CHEBI:77198 biolink:ChemicalSubstance 6-sulfo-D-quinovose go-plus.json http://purl.obolibrary.org/obo/CHEBI_77198 UBERON:0006268 biolink:AnatomicalEntity notochordal process A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot go-plus.json chordamesoderm|presumptive notochord http://purl.obolibrary.org/obo/UBERON_0006268 UBERON:0006256 biolink:AnatomicalEntity knee joint primordium go-plus.json http://purl.obolibrary.org/obo/UBERON_0006256 CHEBI:18887 biolink:ChemicalSubstance cyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18887 chebi_ph7_3 GO:0102791 biolink:MolecularActivity sulfuretin synthase activity Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O. EC:1.21.3.6|MetaCyc:RXN-8008 go-plus.json http://purl.obolibrary.org/obo/GO_0102791 GO:0102790 biolink:MolecularActivity cyanidin 5,3-O-glycosyltransferase activity Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP. MetaCyc:RXN-8006 go-plus.json http://purl.obolibrary.org/obo/GO_0102790 GO:0102793 biolink:MolecularActivity soyasapogenol B glucuronosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate. EC:2.4.1.262|MetaCyc:RXN-8086|RHEA:31475 go-plus.json http://purl.obolibrary.org/obo/GO_0102793 GO:0102792 biolink:MolecularActivity sinapaldehyde:NAD(P)+ oxidoreductase activity Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH. MetaCyc:RXN-8014 go-plus.json http://purl.obolibrary.org/obo/GO_0102792 GO:0102795 biolink:MolecularActivity 1-naphthaldehyde:oxygen oxidoreductase activity Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide. MetaCyc:RXN-8090|EC:1.2.3.9 go-plus.json http://purl.obolibrary.org/obo/GO_0102795 GO:0102794 biolink:MolecularActivity cinnamaldehyde:oxygen oxidoreductase activity Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide. MetaCyc:RXN-8089|EC:1.2.3.9 go-plus.json http://purl.obolibrary.org/obo/GO_0102794 GO:0102797 biolink:MolecularActivity geranial:oxygen oxidoreductase activity Catalysis of the reaction: geranial + O2 + H2O = H+ + geranate + hydrogen peroxide. MetaCyc:RXN-8093|EC:1.2.3.1 go-plus.json http://purl.obolibrary.org/obo/GO_0102797 GO:0102796 biolink:MolecularActivity protocatechualdehyde:oxygen oxidoreductase activity Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide. EC:1.2.3.9|MetaCyc:RXN-8091 go-plus.json http://purl.obolibrary.org/obo/GO_0102796 GO:0102799 biolink:MolecularActivity glucosinolate glucohydrolase activity Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides. EC:3.2.1.147|MetaCyc:RXN-8134 go-plus.json http://purl.obolibrary.org/obo/GO_0102799 GO:0102798 biolink:MolecularActivity heptaldehyde:oxygen oxidoreductase activity Catalysis of the reaction: heptanal + O2 + H2O = H+ + heptanoate + hydrogen peroxide. MetaCyc:RXN-8094|EC:1.2.3.1 go-plus.json http://purl.obolibrary.org/obo/GO_0102798 CHEBI:149 biolink:ChemicalSubstance (-)-dihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_149 chebi_ph7_3 CHEBI:155 biolink:ChemicalSubstance (-)-isodihydrocarvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_155 chebi_ph7_3 CHEBI:154 biolink:ChemicalSubstance (+)-dihydrocarvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_154 chebi_ph7_3 CHEBI:18822 biolink:ChemicalSubstance (Z,Z,Z)-geranylgeraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_18822 chebi_ph7_3 CHEBI:158 biolink:ChemicalSubstance (-)-neodihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_158 chebi_ph7_3 CHEBI:153 biolink:ChemicalSubstance (-)-neoisodihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_153 chebi_ph7_3 CHEBI:152 biolink:ChemicalSubstance (+)-neodihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_152 chebi_ph7_3 CHEBI:151 biolink:ChemicalSubstance D-threo-isocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_151 CHEBI:150 biolink:ChemicalSubstance (-)-isodihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_150 chebi_ph7_3 CHEBI:168 biolink:ChemicalSubstance (-)-dihydrocarvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_168 chebi_ph7_3 CHEBI:18859 biolink:ChemicalSubstance 1,2,3-tribromopropane go-plus.json http://purl.obolibrary.org/obo/CHEBI_18859 chebi_ph7_3 CHEBI:166 biolink:ChemicalSubstance (+)-isodihydrocarvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_166 chebi_ph7_3 CHEBI:165 biolink:ChemicalSubstance (1S,4R)-fenchone go-plus.json http://purl.obolibrary.org/obo/CHEBI_165 chebi_ph7_3 CHEBI:160 biolink:ChemicalSubstance D-erythro-isocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_160 UBERON:0006292 biolink:AnatomicalEntity shoulder joint primordium go-plus.json http://purl.obolibrary.org/obo/UBERON_0006292 UBERON:0006291 biolink:AnatomicalEntity scapula pre-cartilage condensation A scapula endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006291 UBERON:0006290 biolink:AnatomicalEntity scapula cartilage element A scapula endochondral element that is composed primarily of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006290 UBERON:0006298 biolink:AnatomicalEntity submandibular gland primordium A primordium that has the potential to develop into a submandibular gland. go-plus.json submaxillary gland primordium http://purl.obolibrary.org/obo/UBERON_0006298 UBERON:0006293 biolink:AnatomicalEntity spleen primordium A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]. go-plus.json spleen mesenchyme|splenic mesenchyme|left spleen primordium|splenic primordium http://purl.obolibrary.org/obo/UBERON_0006293 GO:0004404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004404 GO:0004403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004403 GO:0004406 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004406 GO:0004405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004405 GO:0004400 biolink:MolecularActivity histidinol-phosphate transaminase activity Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. RHEA:23744|EC:2.6.1.9|MetaCyc:HISTAMINOTRANS-RXN go-plus.json imidazoleacetol phosphate transaminase activity|glutamic-imidazoleacetol phosphate transaminase activity|imidazolylacetolphosphate aminotransferase activity|IAP transaminase activity|imidazole acetol-phosphate transaminase activity|L-histidinol phosphate aminotransferase activity|histidinol phosphate aminotransferase activity|L-histidinol-phosphate:2-oxoglutarate aminotransferase activity|imidazolylacetolphosphate transaminase activity|histidine:imidazoleacetol phosphate transaminase activity|histidinol-phosphate aminotransferase activity http://purl.obolibrary.org/obo/GO_0004400 CHEBI:53128 biolink:ChemicalSubstance Se-methylselenocysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53128 GO:0004402 biolink:MolecularActivity histone acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. Reactome:R-HSA-3318413|Reactome:R-HSA-3451147|Reactome:R-HSA-3321975|Reactome:R-HSA-3301345|RHEA:21992|Reactome:R-HSA-5250938|Reactome:R-HSA-3662318|Reactome:R-HSA-3697920|MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-5144542|Reactome:R-HSA-3321805|Reactome:R-HSA-3697008|Reactome:R-HSA-3318486|Reactome:R-HSA-3318415|Reactome:R-HSA-3301237|Reactome:R-HSA-3321883|Reactome:R-HSA-3662335|EC:2.3.1.48 go-plus.json acetyl-CoA:histone acetyltransferase activity|H2A/H2B histone acetyltransferase activity|histone transacetylase activity|histone acetokinase activity|H4/H2 histone acetyltransferase activity|nucleosome-histone acetyltransferase activity|H4/H2A acetyltransferase activity|H3/H4 histone acetyltransferase activity|histone acetylase activity|histone lysine acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004402 NCBITaxon:424574 biolink:OrganismalEntity Solaneae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_424574 CHEBI:53129 biolink:ChemicalSubstance Se-methyl-D-selenocysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53129 GO:0004401 biolink:MolecularActivity histidinol-phosphatase activity Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate. KEGG_REACTION:R03013|RHEA:14465|MetaCyc:HISTIDPHOS-RXN|EC:3.1.3.15 go-plus.json histidinol phosphate phosphatase activity|L-histidinol phosphate phosphatase activity|HPpase activity|L-histidinol-phosphate phosphohydrolase activity|histidinolphosphate phosphatase activity|histidinolphosphatase activity http://purl.obolibrary.org/obo/GO_0004401 CHEBI:28168 biolink:ChemicalSubstance 6-oxocyclohex-1-ene-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28168 CHEBI:28164 biolink:ChemicalSubstance cholesterol beta-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28164 chebi_ph7_3 CHEBI:28163 biolink:ChemicalSubstance iron(III) hydroxamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28163 UBERON:0006322 biolink:AnatomicalEntity inferior rectus extraocular muscle A muscle in the orbit that depresses, adducts, and helps extort (rotate laterally) the eye. The inferior rectus muscle is the only muscle that is capable of depressing the pupil when it is in a fully abducted position. go-plus.json m. rectus inferior|ventral rectus|inferior rectus muscle|ventral rectus extraocular muscle|musculus rectus inferior|ventral recti|musculus rectus inferior bulbi|inferior rectus http://purl.obolibrary.org/obo/UBERON_0006322 CHEBI:28171 biolink:ChemicalSubstance 5-hydroxytryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28171 UBERON:0006321 biolink:AnatomicalEntity superior oblique extraocular muscle The superior oblique muscle, or obliquus oculi superior, is a fusiform muscle in the upper, medial side of the orbit whose primary action is downward, lateral rotation of the eye. One of the extraocular muscles, the superior oblique is the only muscle innervated by the trochlear nerve (the fourth cranial nerve). go-plus.json dorsal oblique extraocular muscle|obliquus oculi superior|M. obliquus superior|dorsal oblique extraocular muscles|superior oblique muscle|musculus obliquus superior|musculus obliquus superior bulbi|superior oblique|obliquus superior http://purl.obolibrary.org/obo/UBERON_0006321 CHEBI:28173 biolink:ChemicalSubstance sorbose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28173 CHEBI:53126 biolink:ChemicalSubstance Se-methyl-L-selenocysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53126 CHEBI:53125 biolink:ChemicalSubstance Se-methyl-D-selenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_53125 GO:0004408 biolink:MolecularActivity holocytochrome-c synthase activity Catalysis of the reaction: holocytochrome c = apocytochrome c + heme. EC:4.4.1.17|RHEA:22648|MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN go-plus.json holocytochrome-c apocytochrome-c-lyase (heme-forming)|cytochrome c heme-lyase activity|holocytochrome-c apocytochrome-c-lyase activity|cytochrome c synthase activity|holocytochrome c synthetase activity http://purl.obolibrary.org/obo/GO_0004408 GO:0004407 biolink:MolecularActivity histone deacetylase activity Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. Reactome:R-HSA-3782655|Reactome:R-HSA-2545203|EC:3.5.1.98|Reactome:R-HSA-433672|RHEA:58196|Reactome:R-HSA-3782637|Reactome:R-HSA-6805650|Reactome:R-HSA-2545253|MetaCyc:3.5.1.98-RXN|Reactome:R-HSA-427514|Reactome:R-HSA-3769447|Reactome:R-HSA-3777129 go-plus.json http://purl.obolibrary.org/obo/GO_0004407 GO:0004409 biolink:MolecularActivity homoaconitate hydratase activity Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O. EC:4.2.1.36|RHEA:15485|KEGG_REACTION:R04371|MetaCyc:HOMOACONITATE-HYDRATASE-RXN go-plus.json 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity|(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]|homoaconitase activity|cis-homoaconitase activity|Lys4|HACN activity|LysF http://purl.obolibrary.org/obo/GO_0004409 CHEBI:53121 biolink:ChemicalSubstance adenosine A2A receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_53121 GO:0004415 biolink:MolecularActivity hyalurononglucosaminidase activity Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. Reactome:R-HSA-5693356|Reactome:R-HSA-9036077|Reactome:R-HSA-2160892|EC:3.2.1.35|Reactome:R-HSA-2160874|Reactome:R-HSA-1793209|Reactome:R-HSA-2318585|MetaCyc:3.2.1.35-RXN go-plus.json hyaluronoglucosidase activity|chondroitinase activity|chondroitinase I activity|hyaluronoglucosaminidase activity|hyaluronate 4-glycanohydrolase activity|hyaluronidase activity http://purl.obolibrary.org/obo/GO_0004415 GO:0004414 biolink:MolecularActivity homoserine O-acetyltransferase activity Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA. KEGG_REACTION:R01776|MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.31|RHEA:13701 go-plus.json homoserine acetyltransferase activity|L-homoserine O-acetyltransferase activity|homoserine O-trans-acetylase activity|acetyl-CoA:L-homoserine O-acetyltransferase activity|homoserine transacetylase activity|homoserine-O-transacetylase activity http://purl.obolibrary.org/obo/GO_0004414 CHEBI:77109 biolink:ChemicalSubstance EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77109 GO:0004417 biolink:MolecularActivity hydroxyethylthiazole kinase activity Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+). MetaCyc:THIAZOLSYN3-RXN|KEGG_REACTION:R04448|RHEA:24212|EC:2.7.1.50 go-plus.json ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity|hydroxyethylthiazole kinase (phosphorylating)|4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity http://purl.obolibrary.org/obo/GO_0004417 CHEBI:77108 biolink:ChemicalSubstance EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77108 GO:0004416 biolink:MolecularActivity hydroxyacylglutathione hydrolase activity Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. Reactome:R-HSA-6783221|RHEA:25245|MetaCyc:GLYOXII-RXN|EC:3.1.2.6 go-plus.json glyoxalase II activity|S-(2-hydroxyacyl)glutathione hydrolase activity|S-2-hydroxylacylglutathione hydrolase activity|acetoacetylglutathione hydrolase activity http://purl.obolibrary.org/obo/GO_0004416 CHEBI:77107 biolink:ChemicalSubstance 3-[(1-carboxyvinyl)oxy]benzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77107 GO:0004411 biolink:MolecularActivity homogentisate 1,2-dioxygenase activity Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+). Reactome:R-HSA-71164|EC:1.13.11.5|KEGG_REACTION:R02519|UM-BBD_reactionID:r0105|RHEA:15449|MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN go-plus.json homogentisicase activity|homogentisic oxygenase activity|homogentisate:oxygen 1,2-oxidoreductase (decyclizing)|homogentisate dioxygenase activity|homogentisate oxidase activity|homogentisate oxygenase activity|homogentisic acid oxidase activity|homogentisic acid oxygenase activity http://purl.obolibrary.org/obo/GO_0004411 GO:0004410 biolink:MolecularActivity homocitrate synthase activity Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate. RHEA:12929|EC:2.3.3.14|MetaCyc:HOMOCITRATE-SYNTHASE-RXN|KEGG_REACTION:R00271 go-plus.json acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)|acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity|homocitrate synthetase activity http://purl.obolibrary.org/obo/GO_0004410 NCBITaxon:424564 biolink:OrganismalEntity Capsiceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_424564 GO:0004413 biolink:MolecularActivity homoserine kinase activity Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+). EC:2.7.1.39|RHEA:13985|KEGG_REACTION:R01771|MetaCyc:HOMOSERKIN-RXN go-plus.json homoserine kinase (phosphorylating)|HSK|ATP:L-homoserine O-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004413 GO:0004412 biolink:MolecularActivity homoserine dehydrogenase activity Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+. EC:1.1.1.3|MetaCyc:HOMOSERDEHYDROG-RXN|RHEA:15761 go-plus.json http://purl.obolibrary.org/obo/GO_0004412 NCBITaxon:424562 biolink:OrganismalEntity Nicotianeae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_424562 CHEBI:43797 biolink:ChemicalSubstance L-propargylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_43797 CHEBI:43796 biolink:ChemicalSubstance (S)-lipoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43796 CHEBI:28175 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28175 CHEBI:28177 biolink:ChemicalSubstance theophylline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28177 chebi_ph7_3 UBERON:0006311 biolink:AnatomicalEntity chamber of eyeball A segment of the eyeball that is filled with refractive media go-plus.json eye chamber|eyeball chamber|chamber of eye http://purl.obolibrary.org/obo/UBERON_0006311 CHEBI:28181 biolink:ChemicalSubstance 2',3'-cyclic GMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28181 CHEBI:28180 biolink:ChemicalSubstance but-3-ynal go-plus.json http://purl.obolibrary.org/obo/CHEBI_28180 chebi_ph7_3 CHEBI:43799 biolink:ChemicalSubstance butan-1-amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_43799 CHEBI:77102 biolink:ChemicalSubstance EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77102 CHEBI:53112 biolink:ChemicalSubstance AMP 3'-end residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_53112 GO:0004419 biolink:MolecularActivity hydroxymethylglutaryl-CoA lyase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA. MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN|Reactome:R-HSA-74180|RHEA:24404|Reactome:R-HSA-6788597|EC:4.1.3.4|KEGG_REACTION:R01360 go-plus.json 3-hydroxy-3-methylglutaryl CoA cleaving enzyme|hydroxymethylglutaryl coenzyme A-cleaving enzyme|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)|hydroxymethylglutaryl coenzyme A lyase activity|3-hydroxy-3-methylglutaryl coenzyme A lyase activity|3-hydroxy-3-methylglutarate-CoA lyase activity|3-hydroxy-3-methylglutaryl-CoA lyase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity|HMG-CoA lyase activity http://purl.obolibrary.org/obo/GO_0004419 GO:0004418 biolink:MolecularActivity hydroxymethylbilane synthase activity Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+). Reactome:R-HSA-189406|EC:2.5.1.61|MetaCyc:OHMETHYLBILANESYN-RXN|KEGG_REACTION:R00084|RHEA:13185 go-plus.json porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|uroporphyrinogen synthetase activity|pre-uroporphyrinogen synthase activity|(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity|uroporphyrinogen I synthetase activity|uroporphyrinogen synthase activity|(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|HMB-synthase activity|porphobilinogen deaminase activity|porphobilinogen ammonia-lyase (polymerizing)|uroporphyrinogen I synthase activity http://purl.obolibrary.org/obo/GO_0004418 UBERON:0006314 biolink:AnatomicalEntity bodily fluid Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. go-plus.json body fluid|fluid http://purl.obolibrary.org/obo/UBERON_0006314 UBERON:0006312 biolink:AnatomicalEntity ocular refractive media Body substance in a liquid or semi-solid state in the eyeball which serves to refract light. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006312 CHEBI:77119 biolink:ChemicalSubstance EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77119 CHEBI:77118 biolink:ChemicalSubstance EC 3.5.5.1 (nitrilase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77118 NCBITaxon:424554 biolink:OrganismalEntity Nicotianoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_424554 NCBITaxon:424551 biolink:OrganismalEntity Solanoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_424551 CHEBI:28146 biolink:ChemicalSubstance L-xylonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28146 chebi_ph7_3 CHEBI:28145 biolink:ChemicalSubstance dibenzofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_28145 chebi_ph7_3 CHEBI:43786 biolink:ChemicalSubstance D-glycero-alpha-D-manno-heptose 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_43786 CHEBI:28147 biolink:ChemicalSubstance N(2')-acetylgentamycin C1a go-plus.json http://purl.obolibrary.org/obo/CHEBI_28147 CHEBI:28151 biolink:ChemicalSubstance 5beta,9alpha,10alpha-labda-8(20),13-dien-15-yl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28151 CHEBI:77113 biolink:ChemicalSubstance EC 2.7.11.10 (IkappaB kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77113 CHEBI:77111 biolink:ChemicalSubstance EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77111 CHEBI:77110 biolink:ChemicalSubstance EC 1.21.3.3 (reticuline oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77110 UBERON:0006304 biolink:AnatomicalEntity future trigeminal ganglion go-plus.json trigeminal preganglion|trigeminal V preganglion http://purl.obolibrary.org/obo/UBERON_0006304 CHEBI:77117 biolink:ChemicalSubstance EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77117 CHEBI:53100 biolink:ChemicalSubstance GMP 5'-end residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_53100 CHEBI:77115 biolink:ChemicalSubstance EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77115 CHEBI:77129 biolink:ChemicalSubstance 1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77129 chebi_ph7_3 CHEBI:28159 biolink:ChemicalSubstance D-asparagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28159 CHEBI:28161 biolink:ChemicalSubstance beta-D-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28161 chebi_ph7_3 CHEBI:77124 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77124 CHEBI:77122 biolink:ChemicalSubstance 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77122 CHEBI:77121 biolink:ChemicalSubstance 1-oleoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77121 CHEBI:77128 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77128 chebi_ph7_3 CHEBI:77127 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77127 chebi_ph7_3 CHEBI:77126 biolink:ChemicalSubstance 1,2-diarachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77126 chebi_ph7_3 CHEBI:77125 biolink:ChemicalSubstance 1,2-diarachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77125 chebi_ph7_3 OBO:ddanat#part_of biolink:OntologyClass part of part_of go-plus.json http://purl.obolibrary.org/obo/ddanat#part_of CHEBI:28129 biolink:ChemicalSubstance all-trans-phytofluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28129 chebi_ph7_3 CHEBI:28125 biolink:ChemicalSubstance all-cis-docosa-4,7,10,13,16,19-hexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28125 CHEBI:28120 biolink:ChemicalSubstance L-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28120 CHEBI:28122 biolink:ChemicalSubstance p-cumic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28122 CHEBI:77131 biolink:ChemicalSubstance sinapic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77131 CHEBI:77130 biolink:ChemicalSubstance 1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77130 chebi_ph7_3 CHEBI:77135 biolink:ChemicalSubstance 3-sulfolactaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77135 chebi_ph7_3 CHEBI:77134 biolink:ChemicalSubstance 6-deoxy-6-sulfo-D-fructofuranose 1-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77134 chebi_ph7_3 CHEBI:77133 biolink:ChemicalSubstance 6-deoxy-6-sulfo-D-fructofuranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77133 chebi_ph7_3 CHEBI:77132 biolink:ChemicalSubstance 6-sulfo-D-quinovose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77132 chebi_ph7_3 CHEBI:77139 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77139 chebi_ph7_3 CHEBI:77138 biolink:ChemicalSubstance 3-sulfopropanediol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77138 chebi_ph7_3 CHEBI:77137 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77137 chebi_ph7_3 CHEBI:77136 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77136 chebi_ph7_3 CHEBI:18790 biolink:ChemicalSubstance (S)-mevalonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18790 chebi_ph7_3 CHEBI:28138 biolink:ChemicalSubstance undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28138 CHEBI:28134 biolink:ChemicalSubstance ammelide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28134 chebi_ph7_3 CHEBI:28137 biolink:ChemicalSubstance D-glycero-D-manno-heptose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28137 CHEBI:28130 biolink:ChemicalSubstance 13,14-dihydro-Delta(12)-prostaglandin J2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28130 CHEBI:28133 biolink:ChemicalSubstance S-alkyl-L-cysteine S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28133 UBERON:0006355 biolink:AnatomicalEntity superior vesical vein go-plus.json http://purl.obolibrary.org/obo/UBERON_0006355 CHEBI:28140 biolink:ChemicalSubstance D-quinovose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28140 chebi_ph7_3 CHEBI:77142 biolink:ChemicalSubstance dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77142 chebi_ph7_3 CHEBI:77141 biolink:ChemicalSubstance dTDP-beta-L-evernitrose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77141 chebi_ph7_3 CHEBI:77140 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77140 chebi_ph7_3 CHEBI:77146 biolink:ChemicalSubstance ginsenoside C-K go-plus.json http://purl.obolibrary.org/obo/CHEBI_77146 chebi_ph7_3 CHEBI:77144 biolink:ChemicalSubstance dTDP-beta-L-evernosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77144 chebi_ph7_3 CHEBI:77143 biolink:ChemicalSubstance dTDP-N-hydroxy-beta-L-evernosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77143 chebi_ph7_3 CHEBI:77149 biolink:ChemicalSubstance notoginsenoside R1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_77149 chebi_ph7_3 CHEBI:77148 biolink:ChemicalSubstance ginsenoside Re go-plus.json http://purl.obolibrary.org/obo/CHEBI_77148 chebi_ph7_3 CHEBI:28107 biolink:ChemicalSubstance 2-isopropylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_28107 chebi_ph7_3 CHEBI:28102 biolink:ChemicalSubstance amylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28102 chebi_ph7_3 CHEBI:28101 biolink:ChemicalSubstance N(1),N(12)-diacetylspermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28101 CHEBI:28100 biolink:ChemicalSubstance (1->3)-alpha-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28100 chebi_ph7_3 UBERON:0006340 biolink:AnatomicalEntity fourth ventricle choroid plexus stroma A choroid plexus stroma that is part of a fourth ventricle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006340 CHEBI:77152 biolink:ChemicalSubstance ginsenoside Rb2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_77152 chebi_ph7_3 CHEBI:77150 biolink:ChemicalSubstance ginsenoside F1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_77150 chebi_ph7_3 CHEBI:77157 biolink:ChemicalSubstance ginsenoside C-Y go-plus.json http://purl.obolibrary.org/obo/CHEBI_77157 chebi_ph7_3 CHEBI:77156 biolink:ChemicalSubstance gypenoside LXXV go-plus.json http://purl.obolibrary.org/obo/CHEBI_77156 chebi_ph7_3 UBERON:0006347 biolink:AnatomicalEntity communicating artery An artery that connects two larger arteries. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006347 CHEBI:77159 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77159 chebi_ph7_3 CHEBI:77158 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77158 chebi_ph7_3 PO:0025395 biolink:OntologyClass floral organ A plant organ (PO:0009008) that is part of a flower (PO:0009046). go-plus.json flower organ (exact)|花器官 (Japanese, exact)|órgano floral (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025395 CHEBI:28116 biolink:ChemicalSubstance 5-guanidino-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28116 CHEBI:28119 biolink:ChemicalSubstance 2,3,7,8-tetrachlorodibenzodioxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28119 chebi_ph7_3 CHEBI:28118 biolink:ChemicalSubstance muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28118 CHEBI:28113 biolink:ChemicalSubstance 24,25-dihydrolanosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28113 chebi_ph7_3 CHEBI:43732 biolink:ChemicalSubstance thiazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_43732 chebi_ph7_3 CHEBI:28112 biolink:ChemicalSubstance nickel atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_28112 chebi_ph7_3 CHEBI:28115 biolink:ChemicalSubstance methylcobalamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28115 chebi_ph7_3 CHEBI:77160 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77160 chebi_ph7_3 UBERON:0006331 biolink:AnatomicalEntity brainstem nucleus A nucleus of brain that is part of a brainstem. go-plus.json brain stem nucleus http://purl.obolibrary.org/obo/UBERON_0006331 CHEBI:77164 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77164 chebi_ph7_3 CHEBI:77163 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77163 chebi_ph7_3 CHEBI:77168 biolink:ChemicalSubstance 14-hydroxymyristic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77168 CHEBI:77167 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77167 chebi_ph7_3 UBERON:0006339 biolink:AnatomicalEntity third ventricle choroid plexus stroma A choroid plexus stroma that is part of a third ventricle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006339 CHEBI:77166 biolink:ChemicalSubstance 3-oxo-Delta(1),Delta(4)-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77166 chebi_ph7_3 CHEBI:77165 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77165 chebi_ph7_3 UBERON:0006338 biolink:AnatomicalEntity lateral ventricle choroid plexus stroma A choroid plexus stroma that is part of a lateral ventricle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006338 UBERON:0006334 biolink:AnatomicalEntity posterior lateral line One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. go-plus.json pll http://purl.obolibrary.org/obo/UBERON_0006334 CHEBI:77169 biolink:ChemicalSubstance (3S)-hydroxytetradecanedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77169 GO:0004488 biolink:MolecularActivity methylenetetrahydrofolate dehydrogenase (NADP+) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH. RHEA:22812|KEGG_REACTION:R01220|MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN|EC:1.5.1.5 go-plus.json 5,10-methylenetetrahydrofolate:NADP oxidoreductase activity|5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004488 GO:0004487 biolink:MolecularActivity methylenetetrahydrofolate dehydrogenase (NAD+) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH. MetaCyc:1.5.1.15-RXN|Reactome:R-HSA-6801462|EC:1.5.1.15|KEGG_REACTION:R01218|RHEA:22892 go-plus.json 5,10-methylenetetrahydrofolate dehydrogenase activity|5,10-methylenetetrahydrofolate:NAD+ oxidoreductase http://purl.obolibrary.org/obo/GO_0004487 GO:0004489 biolink:MolecularActivity methylenetetrahydrofolate reductase (NAD(P)H) activity Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+. MetaCyc:1.5.1.20-RXN|EC:1.5.1.20|KEGG_REACTION:R01224|Reactome:R-HSA-200676|KEGG_REACTION:R07168 go-plus.json 5,10-methylenetetrahydrofolic acid reductase activity|5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|5,10-CH(2)-H(4)folate reductase activity|methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|5,10-methylenetetrahydrofolate reductase (FADH2) activity|5,10-CH2-H4folate reductase activity|5,10-methylenetetrahydrofolate reductase (FADH) activity|MTHFR activity|5,10-methylenetetrahydropteroylglutamate reductase activity|N(5),N(10)-methylenetetrahydrofolate reductase activity|5,10-methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:NAD oxidoreductase activity|5,10-methylenetetrahydrofolate reductase (NADPH) activity|N(5,10)-methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:NADP+ oxidoreductase activity|methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|methylenetetrahydrofolic acid reductase activity|N5,10-methylenetetrahydrofolate reductase activity|methylenetetrahydrofolate reductase (NADPH2)|5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|5-methyltetrahydrofolate:NAD+ oxidoreductase activity|methylenetetrahydrofolate reductase (NADPH(2)) activity|N5,N10-methylenetetrahydrofolate reductase activity|MetF|methylenetetrahydrofolate reductase [NAD(P)H]|5-methyltetrahydrofolate:(acceptor) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004489 GO:0004484 biolink:MolecularActivity mRNA guanylyltransferase activity Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue. Reactome:R-HSA-77081|EC:2.7.7.50|MetaCyc:MRNA-GUANYLYLTRANSFERASE-RXN|Reactome:R-HSA-77083|RHEA:54592 go-plus.json messenger RNA guanylyltransferase activity|protein lambda2|GTP:mRNA guanylyltransferase activity|mRNA capping enzyme activity|GTP--RNA guanylyltransferase activity http://purl.obolibrary.org/obo/GO_0004484 GO:0004483 biolink:MolecularActivity mRNA (nucleoside-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine. Reactome:R-HSA-9694721|Reactome:R-HSA-9694499|Reactome:R-HSA-9694521|EC:2.1.1.57|Reactome:R-HSA-9684033|Reactome:R-HSA-9684032|Reactome:R-HSA-9684030|MetaCyc:2.1.1.57-RXN go-plus.json S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity|messenger RNA (nucleoside-2'-)-methyltransferase activity|mRNA (adenosine-2'-O-)-methyltransferase activity|messenger ribonucleate nucleoside 2'-methyltransferase activity http://purl.obolibrary.org/obo/GO_0004483 GO:0004486 biolink:MolecularActivity methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+. Reactome:R-HSA-200644|Reactome:R-HSA-200718|EC:1.5.1.5 go-plus.json 5,10-methylene-THF dehydrogenase activity|N5,N10-methylenetetrahydrofolate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004486 GO:0004485 biolink:MolecularActivity methylcrotonoyl-CoA carboxylase activity Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate. Reactome:R-HSA-508308|MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN|RHEA:13589|Reactome:R-HSA-70773|KEGG_REACTION:R04138|EC:6.4.1.4 go-plus.json methylcrotonyl coenzyme A carboxylase activity|beta-methylcrotonyl-CoA carboxylase activity|beta-methylcrotonyl coenzyme A carboxylase activity|methylcrotonyl-CoA carboxylase activity|beta-methylcrotonyl CoA carboxylase activity|MCCC activity|3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0004485 GO:0004480 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004480 GO:0004482 biolink:MolecularActivity mRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine. Reactome:R-HSA-9694737|Reactome:R-HSA-77090|Reactome:R-HSA-9684016|Reactome:R-HSA-9694476|Reactome:R-HSA-9684018|EC:2.1.1.56|Reactome:R-HSA-9684017|MetaCyc:MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|Reactome:R-HSA-9694492 go-plus.json messenger ribonucleate guanine 7-methyltransferase activity|guanine-7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity|messenger RNA guanine 7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0004482 GO:0004481 biolink:MolecularActivity methylene-fatty-acyl-phospholipid synthase activity Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid. EC:2.1.1.16|RHEA:17549|MetaCyc:2.1.1.16-RXN go-plus.json cyclopropane synthetase activity|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)|unsaturated-phospholipid methyltransferase activity http://purl.obolibrary.org/obo/GO_0004481 GO:0004499 biolink:MolecularActivity N,N-dimethylaniline monooxygenase activity Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O. RHEA:24468|Reactome:R-HSA-217255|MetaCyc:1.14.13.8-RXN|EC:1.14.13.8|Reactome:R-HSA-5602966|Reactome:R-HSA-139970 go-plus.json mixed-function amine oxidase activity|dimethylaniline monooxygenase (N-oxide-forming) activity|flavin monooxygenase activity|flavin-containing monooxygenase activity|methylphenyltetrahydropyridine N-monooxygenase activity|dimethylaniline oxidase activity|dimethylaniline N-oxidase activity|FAD-containing monooxygenase activity|FMO5|Ziegler's enzyme|FMO4|FMO3|FMO2|1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity|FMO1|DMA oxidase activity|FMO activity|FMO-II|FMO-I|flavin mixed function oxidase activity|N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming) http://purl.obolibrary.org/obo/GO_0004499 GO:0004498 biolink:MolecularActivity calcidiol 1-monooxygenase activity Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+). KEGG_REACTION:R03610|Reactome:R-HSA-209868|RHEA:20573|MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN|EC:1.14.15.18|Reactome:R-HSA-5602186 go-plus.json cytochrome P450 CYP27B|25-hydroxyvitamin D-1 alpha hydroxylase activity|25-hydroxycholecalciferol 1-monooxygenase activity|25-OHD-1 alpha-hydroxylase activity|25-hydroxy vitamin D3 1-alpha-hydroxylase activity|25-hydroxyvitamin D3 1alpha-hydroxylase activity|1-hydroxylase-25-hydroxyvitamin D3 activity|calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)|25-hydroxy D3-1alpha-hydroxylase activity|25-hydroxycholecalciferol 1alpha-hydroxylase activity|25-hydroxycholecalciferol 1-hydroxylase activity|25-hydroxycholecalciferol-1-hydroxylase activity http://purl.obolibrary.org/obo/GO_0004498 GO:0004495 biolink:MolecularActivity mevaldate reductase activity Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0004495 GO:0004494 biolink:MolecularActivity methylmalonyl-CoA mutase activity Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA. RHEA:22888|Reactome:R-HSA-71010|Reactome:R-HSA-3322971|MetaCyc:METHYLMALONYL-COA-MUT-RXN|UM-BBD_reactionID:r0922|EC:5.4.99.2|KEGG_REACTION:R00833 go-plus.json (R)-methylmalonyl-CoA CoA-carbonylmutase activity|methylmalonyl-CoA CoA-carbonyl mutase activity|(S)-methylmalonyl-CoA mutase activity|methylmalonyl coenzyme A mutase activity|methylmalonyl coenzyme A carbonylmutase activity|(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity http://purl.obolibrary.org/obo/GO_0004494 GO:0004497 biolink:MolecularActivity monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Reactome:R-HSA-5423678|Reactome:R-HSA-5662662|Reactome:R-HSA-211962|Reactome:R-HSA-5602295|Reactome:R-HSA-76416|Reactome:R-HSA-212005|Reactome:R-HSA-211959|Reactome:R-HSA-76434|Reactome:R-HSA-211951|Reactome:R-HSA-76426|Reactome:R-HSA-211960|Reactome:R-HSA-5662692|Reactome:R-HSA-215526|Reactome:R-HSA-9027042|Reactome:R-HSA-211919|Reactome:R-HSA-9027302|Reactome:R-HSA-5605147|Reactome:R-HSA-76354|Reactome:R-HSA-9018874|Reactome:R-HSA-9027321|Reactome:R-HSA-211948|Reactome:R-HSA-76397|Reactome:R-HSA-5423664|Reactome:R-HSA-6786239|Reactome:R-HSA-2161814|Reactome:R-HSA-211991|Reactome:R-HSA-211882|Reactome:R-HSA-9027043|Reactome:R-HSA-2161899|Reactome:R-HSA-5423647|Reactome:R-HSA-8865107|Reactome:R-HSA-9027044|Reactome:R-HSA-212004|Reactome:R-HSA-2162191|Reactome:R-HSA-211910|Reactome:R-HSA-76373|Reactome:R-HSA-211904|Reactome:R-HSA-2161890|Reactome:R-HSA-5423672|Reactome:R-HSA-5602242|Reactome:R-HSA-156526|Reactome:R-HSA-211929|Reactome:R-HSA-2161795|Reactome:R-HSA-9037761|Reactome:R-HSA-76472|Reactome:R-HSA-217258|Reactome:R-HSA-213175|Reactome:R-HSA-143468|Reactome:R-HSA-211924|Reactome:R-HSA-211988|Reactome:R-HSA-5602272|Reactome:R-HSA-76466|Reactome:R-HSA-2161940|Reactome:R-HSA-76475|Reactome:R-HSA-76386|Reactome:R-HSA-76456|Reactome:R-HSA-5663050|Reactome:R-HSA-211968 go-plus.json hydroxylase activity http://purl.obolibrary.org/obo/GO_0004497 goslim_pir GO:0004496 biolink:MolecularActivity mevalonate kinase activity Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+). MetaCyc:MEVALONATE-KINASE-RXN|EC:2.7.1.36|Reactome:R-HSA-191380|KEGG_REACTION:R02245|RHEA:17065 go-plus.json mevalonate 5-phosphotransferase activity|ATP:mevalonate 5-phosphotransferase activity|mevalonic kinase activity|mevalonate phosphokinase activity|mevalonic acid kinase activity|mevalonate kinase (phosphorylating)|MVA kinase activity|ATP:(R)-mevalonate 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004496 GO:0004491 biolink:MolecularActivity methylmalonate-semialdehyde dehydrogenase (acylating) activity Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+. MetaCyc:1.2.1.27-RXN|Reactome:R-HSA-70893|EC:1.2.1.27|RHEA:20804 go-plus.json MMSA dehydrogenase activity|2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)|MSDH activity http://purl.obolibrary.org/obo/GO_0004491 GO:0004490 biolink:MolecularActivity methylglutaconyl-CoA hydratase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O. KEGG_REACTION:R02085|MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN|Reactome:R-HSA-70785|EC:4.2.1.18|RHEA:21536 go-plus.json methylglutaconyl coenzyme A hydratase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity|3-methylglutaconyl CoA hydratase activity|methylglutaconase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming) http://purl.obolibrary.org/obo/GO_0004490 GO:0004493 biolink:MolecularActivity methylmalonyl-CoA epimerase activity Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. KEGG_REACTION:R02765|RHEA:20553|Reactome:R-HSA-71020|MetaCyc:METHYLMALONYL-COA-EPIM-RXN|EC:5.1.99.1 go-plus.json methylmalonyl coenzyme A racemase activity|2-methyl-3-oxopropanoyl-CoA 2-epimerase activity|methylmalonyl-CoA racemase activity|DL-methylmalonyl-CoA racemase activity|methylmalonyl-CoA 2-epimerase activity http://purl.obolibrary.org/obo/GO_0004493 GO:0102801 biolink:MolecularActivity anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A. MetaCyc:RXN-8139|RHEA:35515|EC:2.3.1.214 go-plus.json http://purl.obolibrary.org/obo/GO_0102801 GO:0004492 biolink:MolecularActivity methylmalonyl-CoA decarboxylase activity Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2. EC:7.2.4.3|RHEA:21396|MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN go-plus.json (S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)|(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity|methylmalonyl-coenzyme A decarboxylase activity|(S)-methylmalonyl-CoA carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0004492 GO:0102800 biolink:MolecularActivity caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A. MetaCyc:RXN-8138 go-plus.json http://purl.obolibrary.org/obo/GO_0102800 GO:0102803 biolink:MolecularActivity thebane O-demethylase activity Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide. EC:1.14.11.32|MetaCyc:RXN-8149 go-plus.json http://purl.obolibrary.org/obo/GO_0102803 GO:0102802 biolink:MolecularActivity thebaine 6-O-demethylase activity Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide. EC:1.14.11.31|MetaCyc:RXN-8147|RHEA:27477 go-plus.json http://purl.obolibrary.org/obo/GO_0102802 GO:0102805 biolink:MolecularActivity codeine O-demethylase activity Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide. EC:1.14.11.32|MetaCyc:RXN-8152|RHEA:27413 go-plus.json http://purl.obolibrary.org/obo/GO_0102805 GO:0102804 biolink:MolecularActivity oripavine 6-O-demethylase activity Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide. EC:1.14.11.31|MetaCyc:RXN-8151 go-plus.json http://purl.obolibrary.org/obo/GO_0102804 CHEBI:7916 biolink:ChemicalSubstance pantothenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7916 GO:0102807 biolink:MolecularActivity cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-O-sophoroside + UDP + H+. MetaCyc:RXN-8176 go-plus.json http://purl.obolibrary.org/obo/GO_0102807 GO:0102806 biolink:MolecularActivity 4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity Catalysis of the reaction: 4-coumaryl-CoA + cyanin betaine <=> shisonin + coenzyme A. MetaCyc:RXN-8170 go-plus.json http://purl.obolibrary.org/obo/GO_0102806 GO:0102809 biolink:MolecularActivity delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-beta-D-glucoside <=> H+ + delphinidin 3-O-sophoroside + UDP. MetaCyc:RXN-8178 go-plus.json http://purl.obolibrary.org/obo/GO_0102809 GO:0102808 biolink:MolecularActivity pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + pelargonidin 3-O-beta-D-glucoside <=> H+ + pelargonidin 3-O-sophoroside + UDP. MetaCyc:RXN-8177 go-plus.json http://purl.obolibrary.org/obo/GO_0102808 GO:0004469 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004469 GO:0004466 biolink:MolecularActivity long-chain-acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF. RHEA:17721|MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN|EC:1.3.8.8 go-plus.json long-chain acyl-coenzyme A dehydrogenase activity|palmitoyl-coenzyme A dehydrogenase activity|long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity|long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity|palmitoyl-CoA dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004466 GO:0004465 biolink:MolecularActivity lipoprotein lipase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein. Reactome:R-HSA-174757|Reactome:R-HSA-2395768|Reactome:R-HSA-8979996|Reactome:R-HSA-8980228|Reactome:R-HSA-1482811|MetaCyc:LIPOPROTEIN-LIPASE-RXN|EC:3.1.1.34|Reactome:R-HSA-6789310 go-plus.json clearing factor lipase activity|diacylglycerol hydrolase activity|triacylglycero-protein acylhydrolase activity|diacylglycerol lipase activity|lipemia-clearing factor|postheparin esterase activity|postheparin lipase activity|diglyceride lipase activity http://purl.obolibrary.org/obo/GO_0004465 GO:0004468 biolink:MolecularActivity lysine N-acetyltransferase activity, acting on acetyl phosphate as donor Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine. Reactome:R-HSA-5693001|MetaCyc:LYSINE-N-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-5618328|RHEA:14417|EC:2.3.1.32 go-plus.json lysine N6-acetyltransferase activity|lysine N(6)-acetyltransferase activity|acetyl-phosphate:L-lysine 6-N-acetyltransferase activity|lysine acetyltransferase activity|LAT activity|acetyl-phosphate:L-lysine N6-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004468 GO:0004467 biolink:MolecularActivity long-chain fatty acid-CoA ligase activity Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22. MetaCyc:PWY-5143|RHEA:15421|EC:6.2.1.3|Reactome:R-HSA-193766|Reactome:R-HSA-193727|Reactome:R-HSA-5696004|Reactome:R-HSA-201035|Reactome:R-HSA-192137|Reactome:R-HSA-159425|Reactome:R-HSA-193401|UM-BBD_enzymeID:e0025|Reactome:R-HSA-193407|Reactome:R-HSA-2046098|MetaCyc:ACYLCOASYN-RXN|Reactome:R-HSA-2046085|Reactome:R-HSA-193711|Reactome:R-HSA-548843|Reactome:R-HSA-193424|Reactome:R-HSA-193743 go-plus.json long-chain fatty acyl coenzyme A synthetase activity|long chain fatty acyl-CoA synthetase activity|long-chain fatty acid activation|acyl-CoA ligase activity|long-chain acyl CoA synthetase activity|stearoyl-CoA synthetase|pristanoyl-CoA synthetase|thiokinase|lignoceroyl-CoA synthase activity|long-chain acyl-coenzyme A synthetase activity|fatty acid thiokinase (long-chain) activity|long-chain-fatty-acid-CoA ligase activity|LCFA synthetase activity|long-chain acyl-CoA synthetase activity|long-chain-fatty-acyl-CoA synthetase activity|acyl-activating enzyme activity|acyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0004467 GO:0004462 biolink:MolecularActivity lactoylglutathione lyase activity Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal. RHEA:19069|MetaCyc:GLYOXI-RXN|Reactome:R-HSA-5694071|KEGG_REACTION:R02530|EC:4.4.1.5 go-plus.json (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity|aldoketomutase activity|glyoxalase I activity|glyoxylase I|(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)|ketone-aldehyde mutase activity|methylglyoxalase activity http://purl.obolibrary.org/obo/GO_0004462 GO:0004461 biolink:MolecularActivity lactose synthase activity Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose. MetaCyc:LACTOSE-SYNTHASE-RXN|Reactome:R-HSA-5653878|RHEA:12404|EC:2.4.1.22 go-plus.json UDP-galactose:D-glucose 4-beta-D-galactotransferase activity|UDP-galactose-glucose galactosyltransferase activity|lactose synthetase activity|UDPgalactose:D-glucose 4-beta-D-galactotransferase activity|UDPgalactose-glucose galactosyltransferase activity|uridine diphosphogalactose-glucose galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0004461 GO:0004464 biolink:MolecularActivity leukotriene-C4 synthase activity Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN|Reactome:R-HSA-266050|RHEA:17617|KEGG_REACTION:R03059|EC:4.4.1.20 go-plus.json (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)|LTC4 synthetase activity|LTC(4) synthase activity|(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)|leukotriene A4:glutathione S-leukotrienyltransferase activity|LTC4 synthase activity|leukotriene C(4) synthetase activity|leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)|leukotriene A(4):glutathione S-leukotrienyltransferase activity|LTC(4) synthetase activity|leukotriene C4 synthetase activity http://purl.obolibrary.org/obo/GO_0004464 GO:0004463 biolink:MolecularActivity leukotriene-A4 hydrolase activity Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4). MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN|Reactome:R-HSA-266072|RHEA:22324|KEGG_REACTION:R03057|EC:3.3.2.6 go-plus.json LTA4 hydrolase activity|(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity|LTA-4 hydrolase activity|leukotriene A4 hydrolase activity|LTA4H|leukotriene A(4) hydrolase activity http://purl.obolibrary.org/obo/GO_0004463 GO:0102810 biolink:MolecularActivity glutarate-semialdehyde dehydrogenase (NADP+) activity Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+. MetaCyc:RXN-8182|RHEA:57832 go-plus.json http://purl.obolibrary.org/obo/GO_0102810 GO:0004460 biolink:MolecularActivity L-lactate dehydrogenase (cytochrome) activity Catalysis of the reaction: (S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate. EC:1.1.2.3|MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:19909 go-plus.json lactic acid dehydrogenase activity|lactate dehydrogenase (cytochrome)|cytochrome b2|cytochrome b2 (flavin-free derivative of flavocytochrome b2)|flavocytochrome b2|dehydrogenase, lactate (cytochrome)|(S)-lactate:ferricytochrome-c 2-oxidoreductase activity|L-lactate cytochrome c reductase activity|L(+)-lactate:cytochrome c oxidoreductase activity|lactic cytochrome c reductase activity|L-lactate ferricytochrome c oxidoreductase activity|L-lactate cytochrome c oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004460 GO:0102812 biolink:MolecularActivity 4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A. MetaCyc:RXN-8204 go-plus.json http://purl.obolibrary.org/obo/GO_0102812 GO:0102811 biolink:MolecularActivity geraniol 10-hydroxylase activity Catalysis of the reaction: geraniol + O2 + NADPH + H+ <=> (6E)-8-hydroxygeraniol + NADP + H2O. RHEA:32495|EC:1.14.14.83|MetaCyc:RXN-8197 go-plus.json http://purl.obolibrary.org/obo/GO_0102811 GO:0102814 biolink:MolecularActivity caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity Catalysis of the reaction: delphinidin 3,3',5-tri-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + coenzyme A. MetaCyc:RXN-8232 go-plus.json http://purl.obolibrary.org/obo/GO_0102814 GO:0102813 biolink:MolecularActivity UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+. MetaCyc:RXN-8205 go-plus.json http://purl.obolibrary.org/obo/GO_0102813 GO:0102816 biolink:MolecularActivity UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP. RHEA:35423|EC:2.4.1.298|MetaCyc:RXN-8234 go-plus.json http://purl.obolibrary.org/obo/GO_0102816 GO:0102815 biolink:MolecularActivity caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A. EC:2.3.1.153|MetaCyc:RXN-8233 go-plus.json http://purl.obolibrary.org/obo/GO_0102815 CHEBI:53183 biolink:ChemicalSubstance apo carotenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53183 GO:0102818 biolink:MolecularActivity lycopene cleavage oxygenase activity Catalysis of the reaction: lycopene + 2 O2 <=> 2 sulcatone + bixin aldehyde. MetaCyc:RXN-8236 go-plus.json http://purl.obolibrary.org/obo/GO_0102818 GO:0102817 biolink:MolecularActivity caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A. MetaCyc:RXN-8235 go-plus.json http://purl.obolibrary.org/obo/GO_0102817 GO:0102819 biolink:MolecularActivity bixin aldehyde dehydrogenase activity Catalysis of the reaction: bixin aldehyde + O2 + NAD <=> norbixin + NADH + H+. MetaCyc:RXN-8237 go-plus.json http://purl.obolibrary.org/obo/GO_0102819 CHEBI:53186 biolink:ChemicalSubstance apo carotenoid diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53186 CHEBI:53185 biolink:ChemicalSubstance apo carotenoid C35 terpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53185 GO:0004477 biolink:MolecularActivity methenyltetrahydrofolate cyclohydrolase activity Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate. Reactome:R-HSA-200661|MetaCyc:METHENYLTHFCYCLOHYDRO-RXN|EC:3.5.4.9|RHEA:23700|Reactome:R-HSA-200740|Reactome:R-HSA-6801328 go-plus.json citrovorum factor cyclodehydrase activity|formyl-methenyl-methylenetetrahydrofolate synthetase (combined)|5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)|5,10-methenyl-THF cyclohydrolase activity http://purl.obolibrary.org/obo/GO_0004477 GO:0004476 biolink:MolecularActivity mannose-6-phosphate isomerase activity Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate. Reactome:R-HSA-532549|MetaCyc:MANNPISOM-RXN|EC:5.3.1.8|RHEA:12356|Reactome:R-HSA-3781832 go-plus.json D-mannose-6-phosphate aldose-ketose-isomerase activity|phosphohexomutase activity|phosphomannoisomerase activity|D-mannose-6-phosphate ketol-isomerase activity|mannose phosphate isomerase activity|phosphomannose isomerase activity|phosphohexoisomerase activity http://purl.obolibrary.org/obo/GO_0004476 GO:0004479 biolink:MolecularActivity methionyl-tRNA formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA. EC:2.1.2.9|RHEA:24380|Reactome:R-HSA-5389841|MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN go-plus.json N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|methionyl-tRNA Met formyltransferase activity|formylmethionyl-transfer ribonucleic synthetase activity|mitochondrial N-terminal peptidyl-methionine N-formylation|N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|methionyl-transfer ribonucleic transformylase activity|methionyl-transfer ribonucleate methyltransferase activity|conversion of mitochondrial met-tRNAf to fmet-tRNA|methionyl-tRNA transformylase activity|methionyl-transfer RNA transformylase activity|10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity|methionyl ribonucleic formyltransferase activity|N-terminal peptidyl-methionine N-formylation|conversion of met-tRNAf to fmet-tRNA http://purl.obolibrary.org/obo/GO_0004479 GO:0004478 biolink:MolecularActivity methionine adenosyltransferase activity Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine. Reactome:R-HSA-5603114|Reactome:R-HSA-174391|EC:2.5.1.6|Reactome:R-HSA-5603087|RHEA:21080|MetaCyc:S-ADENMETSYN-RXN go-plus.json adenosylmethionine synthetase activity|S-adenosylmethionine synthetase activity|methionine-activating enzyme|ATP:L-methionine S-adenosyltransferase activity|methionine S-adenosyltransferase activity|S-adenosyl-L-methionine synthetase activity|S-adenosylmethionine synthase activity|AdoMet synthetase activity|ATP-methionine adenosyltransferase activity http://purl.obolibrary.org/obo/GO_0004478 GO:0004473 biolink:MolecularActivity malate dehydrogenase (decarboxylating) (NADP+) activity Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+. KEGG_REACTION:R00216|EC:1.1.1.40|MetaCyc:MALIC-NADP-RXN|Reactome:R-HSA-9012349|Reactome:R-HSA-9012036|RHEA:18253 go-plus.json NADP-malic enzyme activity|NADP-specific malic enzyme|(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|malate dehydrogenase (NADP, decarboxylating)|malate dehydrogenase (decarboxylating, NADP)|'malic' enzyme|NADP-specific malate dehydrogenase activity|NADP-linked decarboxylating malic enzyme|L-malate:NADP oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004473 GO:0004472 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004472 GO:0004475 biolink:MolecularActivity mannose-1-phosphate guanylyltransferase activity Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose. Reactome:R-HSA-446221|KEGG_REACTION:R00885|RHEA:15229|EC:2.7.7.13|MetaCyc:2.7.7.13-RXN go-plus.json PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)|GTP-mannose-1-phosphate guanylyltransferase activity|guanosine 5'-diphospho-D-mannose pyrophosphorylase activity|mannose 1-phosphate guanylyltransferase (guanosine triphosphate)|GDP-mannose pyrophosphorylase activity|GTP:mannose-1-phosphate guanylyltransferase activity|guanosine diphosphomannose pyrophosphorylase activity|GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity|guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity http://purl.obolibrary.org/obo/GO_0004475 GO:0004474 biolink:MolecularActivity malate synthase activity Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+). EC:2.3.3.9|KEGG_REACTION:R00472|MetaCyc:MALSYN-RXN|RHEA:18181 go-plus.json L-malate glyoxylate-lyase (CoA-acetylating) activity|acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|malate condensing enzyme activity|glyoxylate transacetylase activity|malic-condensing enzyme activity|malate synthetase activity|glyoxylic transacetase activity|malic synthetase activity|glyoxylate transacetase activity http://purl.obolibrary.org/obo/GO_0004474 GO:0102821 biolink:MolecularActivity bixin methyltransferase activity Catalysis of the reaction: bixin + S-adenosyl-L-methionine <=> bixin dimethyl ester + S-adenosyl-L-homocysteine. MetaCyc:RXN-8239 go-plus.json http://purl.obolibrary.org/obo/GO_0102821 GO:0102820 biolink:MolecularActivity norbixin methyltransferase activity Catalysis of the reaction: norbixin + S-adenosyl-L-methionine <=> bixin + S-adenosyl-L-homocysteine. MetaCyc:RXN-8238 go-plus.json http://purl.obolibrary.org/obo/GO_0102820 GO:0004471 biolink:MolecularActivity malate dehydrogenase (decarboxylating) (NAD+) activity Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. KEGG_REACTION:R00214|RHEA:12653|MetaCyc:1.1.1.39-RXN|Reactome:R-HSA-9012268|MetaCyc:MALIC-NAD-RXN|EC:1.1.1.39|EC:1.1.1.38 go-plus.json NAD-specific malic enzyme|NAD-malic enzyme activity|(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)|NAD-linked malic enzyme|malate dehydrogenase (decarboxylating) activity|(S)-malate:NAD+ oxidoreductase (decarboxylating)|'malic' enzyme|malate dehydrogenase (oxaloacetate-decarboxylating) activity http://purl.obolibrary.org/obo/GO_0004471 GO:0102823 biolink:MolecularActivity kaempferol-3-rhamnoside-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol-3-rhamnoside <=> kaempferol 3-O-rhamnoside-7-O-glucoside + UDP. MetaCyc:RXN-8266 go-plus.json http://purl.obolibrary.org/obo/GO_0102823 GO:0004470 biolink:MolecularActivity malic enzyme activity Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate. go-plus.json pyruvic-malic carboxylase activity http://purl.obolibrary.org/obo/GO_0004470 GO:0102822 biolink:MolecularActivity quercetin 3'-O-methyltransferase activity Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine = H+ + isorhamnetin + S-adenosyl-L-homocysteine. EC:2.1.1.42|MetaCyc:RXN-8262|RHEA:55332 go-plus.json http://purl.obolibrary.org/obo/GO_0102822 CHEBI:53171 biolink:ChemicalSubstance 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial go-plus.json http://purl.obolibrary.org/obo/CHEBI_53171 chebi_ph7_3 GO:0102825 biolink:MolecularActivity quercetin 3-O-rhamnoside-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP. MetaCyc:RXN-8268 go-plus.json http://purl.obolibrary.org/obo/GO_0102825 GO:0102824 biolink:MolecularActivity UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose <=> H+ + quercetin 3-O-rhamnoside + UDP. MetaCyc:RXN-8267|RHEA:61160 go-plus.json http://purl.obolibrary.org/obo/GO_0102824 GO:0102827 biolink:MolecularActivity galactosylononitol-raffinose galactosyltransferase activity Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol. MetaCyc:RXN-8282 go-plus.json http://purl.obolibrary.org/obo/GO_0102827 CHEBI:53173 biolink:ChemicalSubstance (3R)-hydroxy-beta-ionone go-plus.json http://purl.obolibrary.org/obo/CHEBI_53173 chebi_ph7_3 GO:0102826 biolink:MolecularActivity kaempferol-3-glucoside-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP. MetaCyc:RXN-8270 go-plus.json http://purl.obolibrary.org/obo/GO_0102826 GO:0102829 biolink:MolecularActivity ajugose synthase activity Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose. MetaCyc:RXN-8285 go-plus.json http://purl.obolibrary.org/obo/GO_0102829 GO:0102828 biolink:MolecularActivity stachyose galactinol:verbascose galactosyltransferase activity Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol. MetaCyc:RXN-8284 go-plus.json http://purl.obolibrary.org/obo/GO_0102828 CHEBI:53175 biolink:ChemicalSubstance 13-apo-beta-carotenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_53175 chebi_ph7_3 CHEBI:53177 biolink:ChemicalSubstance beta-cyclocitral go-plus.json http://purl.obolibrary.org/obo/CHEBI_53177 chebi_ph7_3 CHEBI:53176 biolink:ChemicalSubstance 4-methylocta-2,4,6-trienedial go-plus.json http://purl.obolibrary.org/obo/CHEBI_53176 chebi_ph7_3 GO:0004448 biolink:MolecularActivity isocitrate dehydrogenase activity Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor. MetaCyc:ISOCITDEH-RXN go-plus.json isocitric dehydrogenase activity|IDP activity|oxalosuccinate decarboxylase activity|oxalosuccinate carboxylase activity|oxalsuccinic decarboxylase activity|beta-ketoglutaric-isocitric carboxylase activity|isocitric acid dehydrogenase activity|IDH activity|IDP3|IDP2|IDP1 http://purl.obolibrary.org/obo/GO_0004448 GO:0004447 biolink:MolecularActivity iodide peroxidase activity Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O. EC:1.11.1.8|MetaCyc:IODIDE-PEROXIDASE-RXN go-plus.json iodinase activity|TPO activity|thyroperoxidase activity|thyroid peroxidase activity http://purl.obolibrary.org/obo/GO_0004447 GO:0004449 biolink:MolecularActivity isocitrate dehydrogenase (NAD+) activity Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+. RHEA:23632|MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN|Reactome:R-HSA-70967|EC:1.1.1.41 go-plus.json nicotinamide adenine dinucleotide isocitrate dehydrogenase activity|NAD isocitric dehydrogenase activity|NAD-linked isocitrate dehydrogenase activity|NAD isocitrate dehydrogenase activity|NAD dependent isocitrate dehydrogenase activity|NAD-specific isocitrate dehydrogenase activity|isocitrate:NAD+ oxidoreductase (decarboxylating)|isocitrate dehydrogenase (NAD) activity http://purl.obolibrary.org/obo/GO_0004449 GO:0004444 biolink:MolecularActivity obsolete inositol-1,4,5-trisphosphate 1-phosphatase OBSOLETE. The removal of a phosphate group from the carbon-1 position of D-myo-inositol 1,4,5-trisphosphate. go-plus.json inositol-1,4,5-trisphosphate 1-phosphatase http://purl.obolibrary.org/obo/GO_0004444 GO:0004443 biolink:MolecularActivity obsolete inositol-1,4,-bisphosphate 4-phosphatase OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4-bisphosphate + H2O = D-myo-inositol 3-monophosphate + phosphate. go-plus.json inositol-1,4,-bisphosphate 4-phosphatase http://purl.obolibrary.org/obo/GO_0004443 GO:0004446 biolink:MolecularActivity inositol-hexakisphosphate phosphatase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate. EC:3.1.3.62|MetaCyc:RXN-7920 go-plus.json inositol tetrakisphosphate phosphomonoesterase activity|multiple inositol-polyphosphate phosphatase activity|MIPP activity|1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004446 GO:0004445 biolink:MolecularActivity inositol-polyphosphate 5-phosphatase activity Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. EC:3.1.3.56 go-plus.json type I inositol-polyphosphate phosphatase activity|myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity|InsP3/Ins(1,3,4,5)P4 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|inositol triphosphate 5-phosphomonoesterase activity|inosine triphosphatase activity|inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity|Ins(1,4,5)P3 5-phosphatase activity|inositol 1,4,5-trisphosphate phosphatase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|type II inositol polyphosphate 5-phosphatase activity|type II inositol-1,4,5-trisphosphate 5-phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|Ins(1,4,5)P(3) 5-phosphatase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|5PTase activity|inositol phosphate 5-phosphomonoesterase activity|D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity|Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity http://purl.obolibrary.org/obo/GO_0004445 GO:0004440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004440 GO:0004442 biolink:MolecularActivity obsolete inositol-1,4,-bisphosphate 3-phosphatase OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate. go-plus.json inositol-1,4,-bisphosphate 3-phosphatase http://purl.obolibrary.org/obo/GO_0004442 GO:0004441 biolink:MolecularActivity inositol-1,4-bisphosphate 1-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate. RHEA:15553|MetaCyc:3.1.3.57-RXN|EC:3.1.3.57|Reactome:R-HSA-1855208 go-plus.json inositol-polyphosphate 1-phosphatase activity|inositol polyphosphate 1-phosphatase activity|1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004441 CHEBI:53167 biolink:ChemicalSubstance hydroxy-beta-cyclocitral go-plus.json http://purl.obolibrary.org/obo/CHEBI_53167 chebi_ph7_3 PO:0025338 biolink:OntologyClass collective plant organ structure development stage A plant structure development stage (PO:0009012) that has as primary participant a collective plant structure (PO:0025497). go-plus.json etapa de desarrollo de una estructura colectiva de la planta (Spanish, exact)|集合的植物構造の発生過程 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025338 PO:0025337 biolink:OntologyClass life of whole plant stage A maximal whole plant development stage. go-plus.json 植物体の一生 (Japanese, exact)|vida de la planta entera (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025337 CHEBI:7940 biolink:ChemicalSubstance patchouli alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_7940 chebi_ph7_3 CHEBI:53166 biolink:ChemicalSubstance crocetin dialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_53166 chebi_ph7_3 GO:0004459 biolink:MolecularActivity L-lactate dehydrogenase activity Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+. MetaCyc:L-LACTATE-DEHYDROGENASE-RXN|EC:1.1.1.27|Reactome:R-HSA-6807826|Reactome:R-HSA-71849|RHEA:23444|Reactome:R-HSA-70510 go-plus.json L-lactic acid dehydrogenase activity|L-lactic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004459 GO:0004458 biolink:MolecularActivity D-lactate dehydrogenase (cytochrome) activity Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate. RHEA:13521|EC:1.1.2.4|MetaCyc:D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN go-plus.json D-lactate (cytochrome) dehydrogenase activity|D-lactate-cytochrome c reductase activity|(R)-lactate:ferricytochrome-c 2-oxidoreductase activity|lactic acid dehydrogenase activity|D-lactate ferricytochrome c oxidoreductase activity|cytochrome-dependent D-(-)-lactate dehydrogenase activity|D-(-)-lactic cytochrome c reductase activity http://purl.obolibrary.org/obo/GO_0004458 GO:0004455 biolink:MolecularActivity ketol-acid reductoisomerase activity Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+. EC:1.1.1.86|MetaCyc:ACETOLACTREDUCTOISOM-RXN|RHEA:22068 go-plus.json acetolactate reductoisomerase activity|acetohydroxy acid isomeroreductase activity|acetohydroxy acid reductoisomerase activity|ketol acid reductoisomerase activity|alpha-keto-beta-hydroxylacyl reductoisomerase activity|dihydroxyisovalerate (isomerizing) dehydrogenase activity|reductoisomerase activity|dihydroxyisovalerate dehydrogenase (isomerizing) activity|isomeroreductase activity|2-hydroxy-3-keto acid reductoisomerase activity|(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing) http://purl.obolibrary.org/obo/GO_0004455 GO:0004454 biolink:MolecularActivity ketohexokinase activity Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate. MetaCyc:KETOHEXOKINASE-RXN|Reactome:R-HSA-5656459|EC:2.7.1.3|RHEA:18145|Reactome:R-HSA-70333 go-plus.json ATP:D-fructose 1-phosphotransferase activity|hepatic fructokinase activity|ketohexokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0004454 GO:0004457 biolink:MolecularActivity lactate dehydrogenase activity Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate. go-plus.json http://purl.obolibrary.org/obo/GO_0004457 GO:0004456 biolink:MolecularActivity phosphogluconate dehydratase activity Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O. EC:4.2.1.12|KEGG_REACTION:R02036|RHEA:17277|MetaCyc:PGLUCONDEHYDRAT-RXN go-plus.json 6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)|6-phospho-D-gluconate hydro-lyase activity|gluconate-6-phosphate dehydratase activity|6-phosphogluconate dehydratase activity|6-phosphogluconic dehydrase activity|gluconate 6-phosphate dehydratase activity|6-phosphogluconate dehydrase activity http://purl.obolibrary.org/obo/GO_0004456 GO:0004451 biolink:MolecularActivity isocitrate lyase activity Catalysis of the reaction: isocitrate = glyoxylate + succinate. KEGG_REACTION:R00479|RHEA:13245|EC:4.1.3.1|MetaCyc:ISOCIT-CLEAV-RXN go-plus.json isocitrate glyoxylate-lyase (succinate-forming)|isocitrase activity|isocitrate glyoxylate-lyase activity|ICL activity|isocitratase activity|threo-DS-isocitrate glyoxylate-lyase activity|isocitritase activity http://purl.obolibrary.org/obo/GO_0004451 GO:0004450 biolink:MolecularActivity isocitrate dehydrogenase (NADP+) activity Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+. Reactome:R-HSA-450984|EC:1.1.1.42|RHEA:19629|Reactome:R-HSA-389540|Reactome:R-HSA-389550|MetaCyc:ISOCITDEH-RXN go-plus.json NADP isocitric dehydrogenase activity|NADP-linked isocitrate dehydrogenase activity|isocitrate dehydrogenase (NADP-dependent) activity|isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity|NADP-specific isocitrate dehydrogenase activity|NADP(+)-linked isocitrate dehydrogenase activity|NADP(+)-ICDH activity|NADP-dependent isocitric dehydrogenase activity|NADP(+)-IDH activity|isocitrate dehydrogenase (NADP) activity|dual-cofactor-specific isocitrate dehydrogenase activity|isocitrate:NADP+ oxidoreductase (decarboxylating)|NADP-dependent isocitrate dehydrogenase activity|isocitrate (NADP) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004450 GO:0004453 biolink:MolecularActivity juvenile-hormone esterase activity Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone. EC:3.1.1.59|MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN|RHEA:16393 go-plus.json JH-esterase activity|juvenile hormone carboxyesterase activity|JH esterase activity|methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity|juvenile hormone analog esterase activity http://purl.obolibrary.org/obo/GO_0004453 goslim_chembl GO:0004452 biolink:MolecularActivity isopentenyl-diphosphate delta-isomerase activity Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate. Reactome:R-HSA-191382|KEGG_REACTION:R01123|EC:5.3.3.2|RHEA:23284|MetaCyc:IPPISOM-RXN go-plus.json isopentenyl-diphosphate D-isomerase activity|isopentenyl-diphosphate delta3-delta2-isomerase activity|isopentenylpyrophosphate delta-isomerase activity|IPP isomerase activity|methylbutenylpyrophosphate isomerase activity|isopentenylpyrophosphate isomerase activity http://purl.obolibrary.org/obo/GO_0004452 CHEBI:53157 biolink:ChemicalSubstance 4'-apo-beta-carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_53157 chebi_ph7_3 CHEBI:53156 biolink:ChemicalSubstance polychlorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_53156 CHEBI:53159 biolink:ChemicalSubstance (3R)-3-hydroxy-8'-apo-beta-carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_53159 chebi_ph7_3 CHEBI:53153 biolink:ChemicalSubstance 10'-apo-beta-carotenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_53153 chebi_ph7_3 CHEBI:53152 biolink:ChemicalSubstance palmitoleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_53152 CHEBI:53155 biolink:ChemicalSubstance 2,6-dimethylocta-2,4,6-trienedial go-plus.json http://purl.obolibrary.org/obo/CHEBI_53155 chebi_ph7_3 CHEBI:53154 biolink:ChemicalSubstance 8'-apo-beta,psi-caroten-8'-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_53154 chebi_ph7_3 GO:0004426 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004426 GO:0004425 biolink:MolecularActivity indole-3-glycerol-phosphate synthase activity Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O. RHEA:23476|MetaCyc:IGPSYN-RXN|EC:4.1.1.48 go-plus.json 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]|1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)|indoleglycerol phosphate synthetase activity|indole-3-glycerophosphate synthase activity|indoleglycerol phosphate synthase activity http://purl.obolibrary.org/obo/GO_0004425 GO:0004428 biolink:MolecularActivity obsolete inositol or phosphatidylinositol kinase activity OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. go-plus.json inositol/phosphatidylinositol kinase activity|inositol or phosphatidylinositol kinase activity http://purl.obolibrary.org/obo/GO_0004428 GO:0004427 biolink:MolecularActivity inorganic diphosphatase activity Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate. KEGG_REACTION:R00004|Reactome:R-HSA-449937|Reactome:R-HSA-71732|RHEA:24576|EC:3.6.1.1|Reactome:R-HSA-6788912|MetaCyc:INORGPYROPHOSPHAT-RXN go-plus.json inorganic pyrophosphatase activity|diphosphate phosphohydrolase activity|pyrophosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004427 GO:0004422 biolink:MolecularActivity hypoxanthine phosphoribosyltransferase activity Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. EC:2.4.2.8|KEGG_REACTION:R01132|RHEA:17973|Reactome:R-HSA-74215|MetaCyc:HYPOXANPRIBOSYLTRAN-RXN go-plus.json HPRT|guanine-hypoxanthine phosphoribosyltransferase activity|inosinate pyrophosphorylase activity|inosinic pyrophosphorylase activity|IMP-GMP pyrophosphorylase activity|6-hydroxypurine phosphoribosyltransferase activity|IMP pyrophosphorylase activity|inosine 5'-phosphate pyrophosphorylase activity|IMP diphosphorylase activity|IMP:diphosphate phospho-D-ribosyltransferase activity|hypoxanthine-guanine phosphoribosyltransferase activity|inosinic acid pyrophosphorylase activity|6-mercaptopurine phosphoribosyltransferase activity|HGPRTase activity|purine-6-thiol phosphoribosyltransferase activity|Transphosphoribosidase activity http://purl.obolibrary.org/obo/GO_0004422 GO:0004421 biolink:MolecularActivity hydroxymethylglutaryl-CoA synthase activity Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+). EC:2.3.3.10|RHEA:10188|Reactome:R-HSA-73918|KEGG_REACTION:R01978|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN|Reactome:R-HSA-191323 go-plus.json (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)|3-hydroxy-3-methylglutaryl coenzyme A synthase activity|hydroxymethylglutaryl coenzyme A-condensing enzyme|hydroxymethylglutaryl coenzyme A synthase activity|beta-hydroxy-beta-methylglutaryl-CoA synthase activity|acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity|HMG-CoA synthase activity|(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity|acetoacetyl coenzyme A transacetase activity|3-hydroxy-3-methylglutaryl coenzyme A synthetase activity|3-hydroxy-3-methylglutaryl-coenzyme A synthase activity|3-hydroxy-3-methylglutaryl-CoA synthase activity|3-hydroxy-3-methylglutaryl CoA synthetase activity http://purl.obolibrary.org/obo/GO_0004421 GO:0004424 biolink:MolecularActivity imidazoleglycerol-phosphate dehydratase activity Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O. KEGG_REACTION:R03457|RHEA:11040|MetaCyc:IMIDPHOSDEHYD-RXN|EC:4.2.1.19 go-plus.json imidazoleglycerol phosphate dehydratase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]|IGP dehydratase activity http://purl.obolibrary.org/obo/GO_0004424 GO:0004423 biolink:MolecularActivity iduronate-2-sulfatase activity Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin. EC:3.1.6.13|Reactome:R-HSA-1678650|Reactome:R-HSA-9036046|Reactome:R-HSA-1793182|Reactome:R-HSA-2262743|MetaCyc:3.1.6.13-RXN go-plus.json chondroitinsulfatase|iduronate sulfatase activity|sulfo-L-iduronate sulfatase activity|iduronide-2-sulfate sulfatase activity|iduronate-2-sulphatase activity|L-iduronosulfatase activity|iduronate-2-sulfate sulfatase activity|2-sulfo-L-iduronate 2-sulfatase activity|L-idurono sulfate sulfatase activity|idurono-2-sulfatase activity|iduronate sulfate sulfatase activity|L-iduronate-2-sulfate 2-sulfohydrolase activity|L-iduronate 2-sulfate sulfatase activity|sulfoiduronate sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0004423 CHEBI:28189 biolink:ChemicalSubstance isomaltose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28189 chebi_ph7_3 GO:0004420 biolink:MolecularActivity hydroxymethylglutaryl-CoA reductase (NADPH) activity Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. MetaCyc:1.1.1.34-RXN|KEGG_REACTION:R02082|Reactome:R-HSA-191352|EC:1.1.1.34|RHEA:15989 go-plus.json hydroxymethylglutaryl-CoA reductase activity|3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|HMG-CoA reductase activity http://purl.obolibrary.org/obo/GO_0004420 CHEBI:28185 biolink:ChemicalSubstance kanamycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_28185 CHEBI:28193 biolink:ChemicalSubstance lupanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28193 CHEBI:28192 biolink:ChemicalSubstance 2-demethylmenaquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28192 chebi_ph7_3 CHEBI:28195 biolink:ChemicalSubstance 3alpha-hydroxy-5beta-androstan-17-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28195 chebi_ph7_3 CHEBI:28194 biolink:ChemicalSubstance petroselinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28194 CHEBI:28191 biolink:ChemicalSubstance 6-alpha-maltosylglucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28191 chebi_ph7_3 CHEBI:53146 biolink:ChemicalSubstance (2Z,4E)-2-hydroxymuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53146 PO:0025314 biolink:OntologyClass microsporangium tapetum An tapetum (PO:0025313) that is part of a microsporangium wall (PO:0025307). go-plus.json 小胞子嚢絨毯組織（タペート組織） (Japanese, exact)|tapeto del microsporangio (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025314 PO:0025313 biolink:OntologyClass tapetum A portion of ground tissue (PO:0025059) that is the inner-most layer of a sporangium wall (PO:0025306). go-plus.json tapeto (Spanish, exact)|絨毯組織、タペート組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025313 GO:0004429 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004429 GO:0004437 biolink:MolecularActivity obsolete inositol or phosphatidylinositol phosphatase activity OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. go-plus.json inositol/phosphatidylinositol phosphatase activity|inositol or phosphatidylinositol phosphatase activity http://purl.obolibrary.org/obo/GO_0004437 GO:0004436 biolink:MolecularActivity phosphatidylinositol diacylglycerol-lyase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol. MetaCyc:3.1.4.10-RXN|RHEA:17093|EC:4.6.1.13 go-plus.json 1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)|1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)|1-phosphatidylinositol phosphodiesterase activity|1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)|monophosphatidylinositol phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0004436 GO:0004439 biolink:MolecularActivity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate. Reactome:R-HSA-1675824|Reactome:R-HSA-1676177|EC:3.1.3.36|MetaCyc:PHOSPHATIDYLINOSITOL-BISPHOSPHATASE-RXN|KEGG_REACTION:R04404|RHEA:22764|Reactome:R-HSA-8868648 go-plus.json triphosphoinositide phosphomonoesterase activity|phosphatidylinositol-bisphosphatase activity|phosphatidylinositol 4,5-bisphosphate phosphatase activity|PtdIns(4,5)P(2) 5-phosphatase activity|PI(4,5)P2 5-phosphatase activity|triphosphoinositide phosphatase activity|PtdIns(4,5)P2 5-phosphatase activity|phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0004439 GO:0004438 biolink:MolecularActivity phosphatidylinositol-3-phosphatase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate. Reactome:R-HSA-1676141|Reactome:R-HSA-6809975|MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN|Reactome:R-HSA-6809777|Reactome:R-HSA-6809325|Reactome:R-HSA-1675795|Reactome:R-HSA-1675994|RHEA:12316|Reactome:R-HSA-1676114|EC:3.1.3.64|Reactome:R-HSA-6809720 go-plus.json inositol-1,3-bisphosphate 3-phosphatase activity|inositol-1,4,-bisphosphate 3-phosphatase activity|inositol 1,3-bisphosphate phosphatase activity|1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity|D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity|inositol-polyphosphate 3-phosphatase activity|phosphatidyl-3-phosphate 3-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004438 GO:0004433 biolink:MolecularActivity obsolete 1-phosphatidylinositol-4-phosphate kinase, class IB OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins. go-plus.json 1-phosphatidylinositol-4-phosphate kinase, class IB http://purl.obolibrary.org/obo/GO_0004433 GO:0004432 biolink:MolecularActivity obsolete 1-phosphatidylinositol-4-phosphate kinase, class IA OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events. go-plus.json 1-phosphatidylinositol-4-phosphate kinase, class IA http://purl.obolibrary.org/obo/GO_0004432 GO:0004435 biolink:MolecularActivity phosphatidylinositol phospholipase C activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+). Reactome:R-HSA-111879|Reactome:R-HSA-2730847|Reactome:R-HSA-1855214|Reactome:R-HSA-202407|EC:3.1.4.11|Reactome:R-HSA-9032478|KEGG_REACTION:R03435|Reactome:R-HSA-1855221|RHEA:33179|Reactome:R-HSA-5607735|Reactome:R-HSA-167686|Reactome:R-HSA-1855177|Reactome:R-HSA-622382|MetaCyc:3.1.4.11-RXN go-plus.json monophosphatidylinositol phosphodiesterase activity|PI-PLC activity|phosphoinositide phospholipase C activity|phosphatidylinositol-4,5-bisphosphate hydrolysis|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|phosphoinositidase C activity|triphosphoinositide phosphodiesterase activity|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0004435 GO:0004434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004434 GO:0004431 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004431 GO:0004430 biolink:MolecularActivity 1-phosphatidylinositol 4-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+). MetaCyc:1-PHOSPHATIDYLINOSITOL-KINASE-RXN|Reactome:R-HSA-1675813|EC:2.7.1.67|Reactome:R-HSA-1675883|Reactome:R-HSA-1675974|RHEA:19877|Reactome:R-HSA-1676185|KEGG_REACTION:R03361|Reactome:R-HSA-1675780 go-plus.json PI4-kinase activity|phosphatidylinositol 4-kinase activity|PtdIns-4-kinase activity|type II phosphatidylinositol kinase activity|PI 4-kinase activity|phosphatidylinositol kinase activity|PI4K|PI4K-alpha activity|ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity|phosphatidylinositol kinase (phosphorylating) activity|PI kinase activity http://purl.obolibrary.org/obo/GO_0004430 CHEBI:28197 biolink:ChemicalSubstance daidzein go-plus.json http://purl.obolibrary.org/obo/CHEBI_28197 CHEBI:28196 biolink:ChemicalSubstance erythromycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_28196 CHEBI:28199 biolink:ChemicalSubstance ferrienterobactin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_28199 chebi_ph7_3 CHEBI:7934 biolink:ChemicalSubstance paromomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_7934 CHEBI:7933 biolink:ChemicalSubstance paromamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7933 PO:0025307 biolink:OntologyClass microsporangium wall A sporangium wall (PO:0025306) that is part of a microsporangium (PO:0025202). go-plus.json pared del microsporangio (Spanish, exact)|小胞子嚢壁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025307 PO:0025306 biolink:OntologyClass sporangium wall A cardinal organ part (PO:0025001) that is composed of the outer layers of a sporangium (PO:0025094) and bounds the archesporium (PO:0030074) or plant spores (PO:0025017). go-plus.json pared del esporangio (Spanish, exact)|sporangium jacket layers (exact)|sporangium jacket layer (exact)|胞子嚢壁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025306 CHEBI:53131 biolink:ChemicalSubstance Se-methyl-D-selenocysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_53131 CHEBI:53130 biolink:ChemicalSubstance Se-methyl-L-selenocysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_53130 CHEBI:53132 biolink:ChemicalSubstance Se-methylselenocysteinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_53132 CHEBI:7747 biolink:ChemicalSubstance oleuropein go-plus.json http://purl.obolibrary.org/obo/CHEBI_7747 chebi_ph7_3 CHEBI:7754 biolink:ChemicalSubstance oligonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_7754 CHEBI:7735 biolink:ChemicalSubstance olanzapine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7735 CHEBI:7794 biolink:ChemicalSubstance phosphate monoester go-plus.json http://purl.obolibrary.org/obo/CHEBI_7794 CHEBI:137799 biolink:ChemicalSubstance deoxycholic acid 24-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137799 CHEBI:137791 biolink:ChemicalSubstance cholic acid 24-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137791 CHEBI:137790 biolink:ChemicalSubstance chenodeoxycholic acid 24-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137790 CHEBI:137796 biolink:ChemicalSubstance 2,5,6-triamino-4-hydroxypyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137796 chebi_ph7_3 CHEBI:53091 biolink:ChemicalSubstance carbodiimide go-plus.json http://purl.obolibrary.org/obo/CHEBI_53091 CHEBI:7775 biolink:ChemicalSubstance ononin go-plus.json http://purl.obolibrary.org/obo/CHEBI_7775 chebi_ph7_3 CHEBI:77050 biolink:ChemicalSubstance (S,S)-pavine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77050 CHEBI:468 biolink:ChemicalSubstance poly[(1->4)-beta-D-mannuronic acid] go-plus.json http://purl.obolibrary.org/obo/CHEBI_468 CHEBI:43722 biolink:ChemicalSubstance isomyristic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43722 CHEBI:77051 biolink:ChemicalSubstance 2,3,8,9-tetramethoxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_77051 CHEBI:77055 biolink:ChemicalSubstance argemonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77055 CHEBI:77059 biolink:ChemicalSubstance (+)-argemonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77059 NCBITaxon:6843 biolink:OrganismalEntity Chelicerata go-plus.json chelicerates http://purl.obolibrary.org/obo/NCBITaxon_6843 CHEBI:77061 biolink:ChemicalSubstance 4,8-dimethylnonanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77061 chebi_ph7_3 CHEBI:77060 biolink:ChemicalSubstance 2,3,8,9-tetramethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_77060 CHEBI:77065 biolink:ChemicalSubstance beta-citrylglutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77065 CHEBI:77064 biolink:ChemicalSubstance Ac-Asp-Glu-Glu go-plus.json http://purl.obolibrary.org/obo/CHEBI_77064 CHEBI:77063 biolink:ChemicalSubstance 4,8-dimethylnonanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77063 chebi_ph7_3 CHEBI:43711 biolink:ChemicalSubstance (R)-dihydrolipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_43711 chebi_ph7_3 CHEBI:18743 biolink:ChemicalSubstance (S)-2-trans-abscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18743 CHEBI:77068 biolink:ChemicalSubstance sphingoid 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77068 CHEBI:43703 biolink:ChemicalSubstance beta-L-fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_43703 chebi_ph7_3 CHEBI:77076 biolink:ChemicalSubstance 10-carboxy-13-deoxydaunorubicin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77076 chebi_ph7_3 CHEBI:77075 biolink:ChemicalSubstance (2E)-hexadecenedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77075 chebi_ph7_3 CHEBI:77074 biolink:ChemicalSubstance 4-O-methylrhodomycin D(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77074 chebi_ph7_3 CHEBI:77073 biolink:ChemicalSubstance rhodomycin D(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77073 chebi_ph7_3 CHEBI:488 biolink:ChemicalSubstance 1,2-campholide go-plus.json http://purl.obolibrary.org/obo/CHEBI_488 chebi_ph7_3 CHEBI:77079 biolink:ChemicalSubstance (3R)-hydroxyhexadecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77079 chebi_ph7_3 CHEBI:77077 biolink:ChemicalSubstance 10-carboxy-13-deoxycarminomycin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77077 chebi_ph7_3 CHEBI:77090 biolink:ChemicalSubstance EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77090 CHEBI:77081 biolink:ChemicalSubstance 3-oxohexadecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77081 chebi_ph7_3 CHEBI:77080 biolink:ChemicalSubstance (3S)-hydroxyhexadecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77080 chebi_ph7_3 CHEBI:77087 biolink:ChemicalSubstance O-hexadecanedioyl-L-carnitine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77087 chebi_ph7_3 CHEBI:77086 biolink:ChemicalSubstance O-lauroyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77086 chebi_ph7_3 CHEBI:77085 biolink:ChemicalSubstance hexadecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77085 chebi_ph7_3 CHEBI:77084 biolink:ChemicalSubstance tetradecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77084 chebi_ph7_3 CHEBI:77089 biolink:ChemicalSubstance EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77089 CHEBI:77094 biolink:ChemicalSubstance 1-icosanoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77094 chebi_ph7_3 CHEBI:77093 biolink:ChemicalSubstance 1-icosanoyl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77093 chebi_ph7_3 CHEBI:77092 biolink:ChemicalSubstance fenbendazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_77092 chebi_ph7_3 CHEBI:77091 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77091 chebi_ph7_3 CHEBI:77098 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77098 chebi_ph7_3 CHEBI:77097 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77097 chebi_ph7_3 CHEBI:77096 biolink:ChemicalSubstance 1-palmitoyl-2-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77096 chebi_ph7_3 CHEBI:77099 biolink:ChemicalSubstance (2S)-pristanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77099 chebi_ph7_3 CHEBI:18703 biolink:ChemicalSubstance D-pipecolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_18703 NCBITaxon:6854 biolink:OrganismalEntity Arachnida go-plus.json arachnids|arachnids http://purl.obolibrary.org/obo/NCBITaxon_6854 PR:000015288 biolink:Protein smoothened A frizzled-like G-protein coupled receptor that is a translation product of the human SMO gene or a 1:1 ortholog thereof. go-plus.json SMO|protein Gx|SMOH http://purl.obolibrary.org/obo/PR_000015288 CHEBI:18723 biolink:ChemicalSubstance nicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_18723 GO:0004525 biolink:MolecularActivity ribonuclease III activity Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt. Reactome:R-HSA-426464|EC:3.1.26.3|Reactome:R-HSA-203893|MetaCyc:3.1.26.3-RXN|Reactome:R-HSA-203862 go-plus.json pre-mRNA 3'-end processing endonuclease|RNase III activity|ribonuclease 3 activity http://purl.obolibrary.org/obo/GO_0004525 GO:0004524 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004524 PO:0025023 biolink:OntologyClass collective phyllome structure A collective plant organ structure (PO:0025007) that consists of two or more phyllomes (PO:0006001) originating from the same node or from one or more adjacent nodes with compressed shoot internodes (PO:0005005). go-plus.json floral whorl (narrow)|phyllome whorl (related)|whorl (narrow)|verticil (broad)|cycle (broad)|estructura colectiva del filoma (Spanish, exact)|葉的器官が集まった構造 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025023 GO:0004527 biolink:MolecularActivity exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. go-plus.json exonuclease IX activity http://purl.obolibrary.org/obo/GO_0004527 GO:0004526 biolink:MolecularActivity ribonuclease P activity Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor. EC:3.1.26.5|MetaCyc:3.1.26.5-RXN|Reactome:R-HSA-5696810|Wikipedia:RNase_P go-plus.json tRNA 5' leader endonuclease activity|RNase P http://purl.obolibrary.org/obo/GO_0004526 GO:0004521 biolink:MolecularActivity endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. Reactome:R-HSA-9009941|Reactome:R-HSA-927836|Reactome:R-HSA-426520|Reactome:R-HSA-425923|Reactome:R-HSA-9023909|Reactome:R-HSA-6814555|Reactome:R-HSA-9023912|Reactome:R-HSA-5601910|Reactome:R-HSA-9009936|Reactome:R-HSA-5601887|Reactome:R-HSA-6791223 go-plus.json endonuclease G activity http://purl.obolibrary.org/obo/GO_0004521 GO:0004520 biolink:MolecularActivity endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Reactome:R-HSA-9023941|Reactome:R-HSA-5693608|Reactome:R-HSA-6782224|Reactome:R-HSA-5690988|Reactome:R-HSA-110359|Reactome:R-HSA-6782204|Reactome:R-HSA-5686657|Reactome:R-HSA-5687464|Reactome:R-HSA-5693584|Reactome:R-HSA-5686440 go-plus.json DNA nicking activity|endonuclease G activity http://purl.obolibrary.org/obo/GO_0004520 GO:0004523 biolink:MolecularActivity RNA-DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. EC:3.1.26.4|Reactome:R-HSA-164528|Reactome:R-HSA-164519|Reactome:R-HSA-173769|MetaCyc:3.1.26.4-RXN|Reactome:R-HSA-182859|Reactome:R-HSA-182795 go-plus.json RNase H1 activity|RNase H2 activity|RNase H3 activity|hybrid nuclease activity|RNA*DNA hybrid ribonucleotidohydrolase activity|hybrid ribonuclease activity|ribonuclease H activity|calf thymus ribonuclease H activity|endoribonuclease H (calf thymus)|RNase H activity|hybridase (ribonuclease H)|ribonuclease H1 activity|endoribonuclease H|ribonuclease H2 activity|ribonuclease H3 activity|hybridase activity|endoribonuclease0 H activity http://purl.obolibrary.org/obo/GO_0004523 GO:0004522 biolink:MolecularActivity ribonuclease A activity Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates. EC:4.6.1.18|MetaCyc:3.1.27.5-RXN|Wikipedia:Ribonuclease_A go-plus.json gene S locus-specific glycoproteins|alkaline ribonuclease activity|ribonuclease I activity|endoribonuclease I|pancreatic ribonuclease activity|ribonucleic phosphatase activity|SLSG glycoproteins|ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity|gene S glycoproteins|RNase A activity|S-genotype-assocd. glycoproteins|RNase activity|pancreatic RNase activity|RNase I activity|ceratitis capitata alkaline ribonuclease activity http://purl.obolibrary.org/obo/GO_0004522 CHEBI:28047 biolink:ChemicalSubstance 5beta-cholestane-3alpha,7alpha-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28047 chebi_ph7_3 CHEBI:137818 biolink:ChemicalSubstance 7-oxoglycolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137818 chebi_ph7_3 CHEBI:137817 biolink:ChemicalSubstance hyocholic acid 24-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137817 PR:000005870 biolink:Protein corticotropin-releasing factor receptor 2 A corticotropin-releasing factor receptor that is a translation product of the human CRHR2 gene or a 1:1 ortholog thereof. go-plus.json CRF2R|corticotropin-releasing hormone receptor 2|CRF-RB|CRH-R-2|CRF-R-2|CRFR-2|CRHR2|CRF-R2|CRH2R|CRH-R2 http://purl.obolibrary.org/obo/PR_000005870 CHEBI:28045 biolink:ChemicalSubstance (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28045 CHEBI:28044 biolink:ChemicalSubstance phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28044 CHEBI:137811 biolink:ChemicalSubstance phenolic radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_137811 chebi_ph7_3 CHEBI:137812 biolink:ChemicalSubstance hyodeoxycholic acid 24-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137812 NCBITaxon:1489388 biolink:OrganismalEntity Euteleosteomorpha go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1489388 PR:000005869 biolink:Protein corticotropin-releasing factor receptor 1 A corticotropin-releasing factor receptor that is a translation product of the human CRHR1 gene or a 1:1 ortholog thereof. go-plus.json corticotropin-releasing hormone receptor 1|CRH-R-1|CRF-R-1|CRFR-1|CRHR1|CRFR|CRF-R1|CRHR|CRH-R1|CRFR1 http://purl.obolibrary.org/obo/PR_000005869 GO:0004529 biolink:MolecularActivity exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0004529 PO:0025017 biolink:OntologyClass plant spore A whole plant (PO:0000003) that arises through meiosis and is contained in a spore wall. go-plus.json espora (Spanish, exact)|diaspore (broad)|spore (broad)|植物胞子 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025017 GO:0004528 biolink:MolecularActivity phosphodiesterase I activity Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides. EC:3.1.4.1|MetaCyc:3.1.4.1-RXN go-plus.json alkaline phosphodiesterase activity|5'NPDE activity|5'-PDE activity|PDE I activity|5'-exonuclease activity|exonuclease I activity|5'-PDase activity|orthophosphoric diester phosphohydrolase activity|5'-phosphodiesterase activity|phosphodiesterase activity|5'-nucleotide phosphodiesterase activity|5'-NPDase activity|5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|nucleotide pyrophosphatase/phosphodiesterase I activity|oligonucleate 5'-nucleotidohydrolase activity http://purl.obolibrary.org/obo/GO_0004528 CHEBI:53000 biolink:ChemicalSubstance epitope go-plus.json http://purl.obolibrary.org/obo/CHEBI_53000 GO:0004536 biolink:MolecularActivity deoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. Reactome:R-HSA-6785986|Reactome:R-HSA-211247|Reactome:R-HSA-5685994 go-plus.json caspase-activated deoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0004536 GO:0004535 biolink:MolecularActivity poly(A)-specific ribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. MetaCyc:3.1.13.4-RXN|Reactome:R-HSA-430021|Reactome:R-HSA-429992|Reactome:R-HSA-429955|EC:3.1.13.4 go-plus.json 2',3'-exoribonuclease activity|poly(A)-specific RNase activity|3'-exoribonuclease activity http://purl.obolibrary.org/obo/GO_0004535 GO:0004537 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004537 GO:0004532 biolink:MolecularActivity exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule. Reactome:R-HSA-429961 go-plus.json http://purl.obolibrary.org/obo/GO_0004532 GO:0004531 biolink:MolecularActivity deoxyribonuclease II activity Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products. MetaCyc:3.1.22.1-RXN|EC:3.1.22.1 go-plus.json deoxyribonucleate 3'-nucleotidohydrolase activity|DNase II activity|lysosomal DNase II activity|pancreatic DNase II|acid DNase activity|acid deoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0004531 GO:0004534 biolink:MolecularActivity 5'-3' exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule. EC:3.1.13.-|Reactome:R-HSA-429845 go-plus.json http://purl.obolibrary.org/obo/GO_0004534 GO:0004533 biolink:MolecularActivity exoribonuclease H activity Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. MetaCyc:3.1.13.2-RXN|EC:3.1.13.2 go-plus.json retroviral reverse transcriptase RNaseH http://purl.obolibrary.org/obo/GO_0004533 CHEBI:28058 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28058 CHEBI:137829 biolink:ChemicalSubstance hyocholic acid 6-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137829 CHEBI:28057 biolink:ChemicalSubstance amylopectin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28057 GO:0004530 biolink:MolecularActivity deoxyribonuclease I activity Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products. MetaCyc:3.1.21.1-RXN|EC:3.1.21.1 go-plus.json Escherichia coli endonuclease I|deoxyribonuclease (pancreatic)|thymonuclease activity|DNA endonuclease activity|DNAase activity|deoxyribonuclease A|DNase I|alkaline DNase activity|DNase activity|pancreatic DNase activity|alkaline deoxyribonuclease activity|DNA nuclease activity|deoxyribonucleic phosphatase activity|endodeoxyribonuclease I|dornava|pancreatic deoxyribonuclease|DNA depolymerase activity|dornavac|pancreatic dornase|thymonuclease, dornase activity http://purl.obolibrary.org/obo/GO_0004530 CHEBI:28059 biolink:ChemicalSubstance cis-1,2-dithiane-4,5-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28059 chebi_ph7_3 CHEBI:28054 biolink:ChemicalSubstance o-cresol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28054 chebi_ph7_3 CHEBI:28053 biolink:ChemicalSubstance melibiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28053 chebi_ph7_3 CHEBI:137822 biolink:ChemicalSubstance hyodeoxycholic acid 6-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137822 CHEBI:28061 biolink:ChemicalSubstance alpha-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28061 chebi_ph7_3 OBO:uberon/core#subdivision_of biolink:OntologyClass subdivision of subdivision_of go-plus.json http://purl.obolibrary.org/obo/uberon/core#subdivision_of CHEBI:28063 biolink:ChemicalSubstance o-xylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28063 chebi_ph7_3 CHEBI:137820 biolink:ChemicalSubstance 7-oxotaurodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137820 chebi_ph7_3 CHEBI:137824 biolink:ChemicalSubstance 7-oxoglycodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137824 chebi_ph7_3 PO:0025007 biolink:OntologyClass collective plant organ structure A collective plant structure (PO:0025497) that is a proper part of a whole plant (PO:0000003), and is composed of two or more adjacent plant organs (PO:0009008) and the associated portions of plant tissue (PO:0009007). go-plus.json 集合植物器官構造 (Japanese, exact)|estructura vegetal colectiva de órgano (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025007 PO:0025006 biolink:OntologyClass plant gamete A native plant cell (PO:0025606) that has half the chromosome complement of the sporophyte and is capable of fertilization to create a plant zygote (PO:0000423). go-plus.json 配偶子 (Japanese, exact)|gameta (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025006 PO:0025004 biolink:OntologyClass plant axis An axial plant organ (PO:0009008). go-plus.json 植物軸（軸柱） (Japanese, exact)|plant axes (exact, plural)|eje de la planta (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025004 GO:0004503 biolink:MolecularActivity tyrosinase activity Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates. EC:1.14.18.1|MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN|RHEA:18117 go-plus.json cresolase activity|dopa oxidase|prophenoloxidase activity|phenolase activity|chlorogenic acid oxidase activity|L-tyrosine monooxygenase activity|catecholase|monophenol monooxidase activity|pyrocatechol oxidase|o-diphenol oxidase activity|monophenolase activity|phenol oxidase activity|tyrosine-dopa oxidase activity|chlorogenic oxidase activity|monophenol monooxygenase activity|monophenol oxygenase|prophenol oxidase activity|monophenol oxidase activity|o-diphenol oxidoreductase|N-acetyl-6-hydroxytryptophan oxidase activity|o-diphenol:O2 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004503 GO:0004502 biolink:MolecularActivity kynurenine 3-monooxygenase activity Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+). EC:1.14.13.9|RHEA:20545|MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN|Reactome:R-HSA-71200|KEGG_REACTION:R01960 go-plus.json kynurenine 3-hydroxylase activity|L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)|L-kynurenine-3-hydroxylase activity|kynurenine hydroxylase activity http://purl.obolibrary.org/obo/GO_0004502 PO:0025001 biolink:OntologyClass cardinal organ part A cardinal part of multi-tissue plant structure (PO:0025498) that is a proper part of a plant organ (PO:0009008) and includes portions of plant tissue (PO:0009007) of at least two different types. go-plus.json 基本的な（主要な）器官部 (Japanese, exact)|parte de un órgano cardinal (Spanish, exact)|cardinal part of plant organ (exact) http://purl.obolibrary.org/obo/PO_0025001 GO:0004505 biolink:MolecularActivity phenylalanine 4-monooxygenase activity Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin. RHEA:20273|MetaCyc:PHENYLALANINE-4-MONOOXYGENASE-RXN|Reactome:R-HSA-5649483|Reactome:R-HSA-71118|EC:1.14.16.1 go-plus.json L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)|phenylalanine hydroxylase activity|phenylalaninase activity|phenylalanine 4-hydroxylase activity|PAH activity http://purl.obolibrary.org/obo/GO_0004505 GO:0004504 biolink:MolecularActivity peptidylglycine monooxygenase activity Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O. EC:1.14.17.3|MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN|RHEA:21452 go-plus.json peptide alpha-amide synthase activity|peptidylglycine 2-hydroxylase activity|peptide alpha-amidating enzyme|synthase, peptide alpha-amide|PAM activity|peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)|PAM-B|PAM-A|peptidyl alpha-amidating enzyme activity|peptidylglycine alpha-hydroxylase activity|peptidylglycine alpha-amidating monooxygenase activity|peptide-alpha-amide synthetase activity http://purl.obolibrary.org/obo/GO_0004504 GO:0004501 biolink:MolecularActivity ecdysone 20-monooxygenase activity Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O. RHEA:14021|EC:1.14.99.22|MetaCyc:ECDYSONE-20-MONOOXYGENASE-RXN|KEGG_REACTION:R02374 go-plus.json ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)|alpha-ecdysone C-20 hydroxylase activity|ecdysone 20-hydroxylase activity|ecdysone modification http://purl.obolibrary.org/obo/GO_0004501 GO:0004500 biolink:MolecularActivity dopamine beta-monooxygenase activity Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O. EC:1.14.17.1|MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN|KEGG_REACTION:R02535|Reactome:R-HSA-209891|RHEA:19117 go-plus.json phenylamine beta-hydroxylase activity|dopa beta-hydroxylase activity|SDBH (soluble dopamine beta-monooxygenase)|dopamine beta-oxidase activity|MDBH (membrane-associated dopamine beta-monooxygenase)|dopamine hydroxylase activity|4-(2-aminoethyl)pyrocatechol beta-oxidase activity|dopamine beta-hydroxylase activity|dopamine b-hydroxylase activity|dopamine-B-hydroxylase activity|3,4-dihydroxyphenethylamine beta-oxidase activity|(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity|oxygenase, dopamine beta-mono-|3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) http://purl.obolibrary.org/obo/GO_0004500 CHEBI:28024 biolink:ChemicalSubstance cyanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28024 CHEBI:28026 biolink:ChemicalSubstance plastoquinol-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28026 chebi_ph7_3 CHEBI:28030 biolink:ChemicalSubstance L-2-amino-4-(hydroxymethylphosphinoyl)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28030 GO:0004507 biolink:MolecularActivity steroid 11-beta-monooxygenase activity Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O. EC:1.14.15.4|MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN|Reactome:R-HSA-193997|Reactome:R-HSA-5580292|RHEA:15629|Reactome:R-HSA-5600598|Reactome:R-HSA-194017 go-plus.json steroid 11beta-monooxygenase activity|cytochrome P450 CYP11B2|cytochrome P450 CYP11B1|steroid 11beta-hydroxylase activity|cytochrome p450 XIB1 activity|steroid 11-beta/18-hydroxylase activity|steroid 11beta/18-hydroxylase activity|oxygenase, steroid 11beta -mono-|steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)|steroid 11-beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0004507 GO:0004506 biolink:MolecularActivity squalene monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+). Reactome:R-HSA-191299|RHEA:25282|EC:1.14.14.17|KEGG_REACTION:R02874|MetaCyc:SQUALENE-MONOOXYGENASE-RXN go-plus.json squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity|squalene-2,3-epoxidase activity|squalene epoxidase activity|squalene oxydocyclase activity|squalene 2,3-oxidocyclase activity|squalene-2,3-epoxide cyclase activity|squalene hydroxylase activity http://purl.obolibrary.org/obo/GO_0004506 GO:0004509 biolink:MolecularActivity steroid 21-monooxygenase activity Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O(2) = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H(2)O. Reactome:R-HSA-193981|MetaCyc:STEROID-21-MONOOXYGENASE-RXN|EC:1.14.14.16|Reactome:R-HSA-193964|Reactome:R-HSA-5601976|RHEA:65612 go-plus.json steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)|cytochrome P450 CYP21A1|steroid 21-hydroxylase activity|cytochrome p450 XXIA1 activity|21-hydroxylase activity http://purl.obolibrary.org/obo/GO_0004509 GO:0004508 biolink:MolecularActivity steroid 17-alpha-monooxygenase activity Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O. Reactome:R-HSA-193068|EC:1.14.14.19|Reactome:R-HSA-9035956|Reactome:R-HSA-9035954|Reactome:R-HSA-193099|Reactome:R-HSA-193070|MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN|Reactome:R-HSA-5601843|Reactome:R-HSA-193072 go-plus.json 17alpha-hydroxylase-C17,20 lyase activity|steroid 17-alpha-hydroxylase activity|steroid 17alpha-monooxygenase activity|steroid 17-alpha-hydroxylase-C17-20 lyase activity|steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)|steroid 17alpha-hydroxylase activity|steroid 17alphahydroxylase/17,20 lyase activity|steroid 17-alpha-hydroxylase/17,20 lyase activity|cytochrome P450 CYP17|cytochrome P-450 (P-45017alpha,lyase)|cytochrome P45017alpha|cytochrome p450 XVIIA1 activity http://purl.obolibrary.org/obo/GO_0004508 GO:0004514 biolink:MolecularActivity nicotinate-nucleotide diphosphorylase (carboxylating) activity Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate. KEGG_REACTION:R03348|RHEA:12733|Reactome:R-HSA-197268|MetaCyc:QUINOPRIBOTRANS-RXN|EC:2.4.2.19 go-plus.json nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)|QAPRTase activity|NAD pyrophosphorylase activity|quinolinate phosphoribosyltransferase (decarboxylating) activity|quinolinic acid phosphoribosyltransferase activity|nicotinate-nucleotide pyrophosphorylase (carboxylating) activity|quinolinic phosphoribosyltransferase activity|nicotinate mononucleotide pyrophosphorylase (carboxylating) http://purl.obolibrary.org/obo/GO_0004514 GO:0004513 biolink:MolecularActivity neolactotetraosylceramide alpha-2,3-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide. RHEA:18913|MetaCyc:2.4.99.10-RXN|EC:2.4.99.10 go-plus.json cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity|CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity|SAT-3|sialyltransferase 3 http://purl.obolibrary.org/obo/GO_0004513 GO:0004516 biolink:MolecularActivity nicotinate phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate. KEGG_REACTION:R01724|EC:6.3.4.21|RHEA:36163|Reactome:R-HSA-197186|MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN go-plus.json niacin ribonucleotidase activity|nicotinic acid mononucleotide pyrophosphorylase activity|nicotinic acid phosphoribosyltransferase activity|nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinic acid mononucleotide glycohydrolase activity http://purl.obolibrary.org/obo/GO_0004516 CHEBI:77009 biolink:ChemicalSubstance 5-O-beta-D-mycaminosyl-20-oxotylonolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_77009 GO:0004515 biolink:MolecularActivity nicotinate-nucleotide adenylyltransferase activity Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. EC:2.7.7.18|RHEA:22860|Reactome:R-HSA-197235|Reactome:R-HSA-200512|Reactome:R-HSA-200474|MetaCyc:NICONUCADENYLYLTRAN-RXN go-plus.json ATP:nicotinate-ribonucleotide adenylyltransferase activity|deamido-NAD(+) pyrophosphorylase activity|deamido-NAD(+) diphosphorylase activity|deamido-NAD+ pyrophosphorylase activity|NaMN-ATase activity|nicotinate mononucleotide adenylyltransferase activity|deamidonicotinamide adenine dinucleotide pyrophosphorylase activity|nicotinic acid mononucleotide adenylyltransferase|ATP:nicotinate-nucleotide adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0004515 GO:0004510 biolink:MolecularActivity tryptophan 5-monooxygenase activity Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. RHEA:16709|MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN|EC:1.14.16.4|Reactome:R-HSA-209828 go-plus.json tryptophan hydroxylase activity|tryptophan 5-hydroxylase activity|L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)|indoleacetic acid-5-hydroxylase activity|L-tryptophan hydroxylase activity http://purl.obolibrary.org/obo/GO_0004510 GO:0004512 biolink:MolecularActivity inositol-3-phosphate synthase activity Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form. Reactome:R-HSA-1855178|EC:5.5.1.4|KEGG_REACTION:R07324|MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN|RHEA:10716 go-plus.json glucose 6-phosphate cyclase activity|glucose-6-phosphate inositol monophosphate cycloaldolase activity|glucocycloaldolase activity|inositol 1-phosphate synthatase activity|1L-myo-inositol-1-phosphate lyase (isomerizing)|inositol 1-phosphate synthetase activity|D-glucose 6-phosphate cycloaldolase activity http://purl.obolibrary.org/obo/GO_0004512 GO:0004511 biolink:MolecularActivity tyrosine 3-monooxygenase activity Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O. MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN|RHEA:18201|Reactome:R-HSA-209823|EC:1.14.16.2 go-plus.json tyrosine hydroxylase activity|L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|tyrosine 3-hydroxylase activity|L-tyrosine hydroxylase activity http://purl.obolibrary.org/obo/GO_0004511 CHEBI:137807 biolink:ChemicalSubstance lithocholic acid 24-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137807 NCBITaxon:208964 biolink:OrganismalEntity Pseudomonas aeruginosa PAO1 go-plus.json Pseudomonas sp. PAO1 http://purl.obolibrary.org/obo/NCBITaxon_208964 CHEBI:28038 biolink:ChemicalSubstance 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28038 CHEBI:28037 biolink:ChemicalSubstance N-acetyl-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28037 chebi_ph7_3 CHEBI:28032 biolink:ChemicalSubstance 4'-hydroxyacetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28032 chebi_ph7_3 CHEBI:28031 biolink:ChemicalSubstance prostaglandin E3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28031 CHEBI:28034 biolink:ChemicalSubstance beta-D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28034 chebi_ph7_3 CHEBI:77002 biolink:ChemicalSubstance methoxyisoflavan go-plus.json http://purl.obolibrary.org/obo/CHEBI_77002 CHEBI:77001 biolink:ChemicalSubstance 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77001 chebi_ph7_3 CHEBI:77000 biolink:ChemicalSubstance 1-oleoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77000 chebi_ph7_3 GO:0004518 biolink:MolecularActivity nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0004518 goslim_chembl|goslim_yeast|goslim_plant|goslim_drosophila|goslim_generic GO:0004517 biolink:MolecularActivity nitric-oxide synthase activity Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. Reactome:R-HSA-418436|Reactome:R-HSA-202127|MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN|RHEA:19897|EC:1.14.13.39 go-plus.json L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity|nitric oxide synthase activity|nitric oxide synthetase activity|NO synthase activity|endothelium-derived relaxing factor synthase activity|NADPH-diaphorase activity|nitric-oxide synthetase activity|endothelium-derived relaxation factor-forming enzyme activity http://purl.obolibrary.org/obo/GO_0004517 GO:0004519 biolink:MolecularActivity endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. Reactome:R-HSA-5358518|Reactome:R-HSA-72180|Reactome:R-HSA-5693533|Reactome:R-HSA-5358512|Reactome:R-HSA-5690990 go-plus.json http://purl.obolibrary.org/obo/GO_0004519 PO:0025066 biolink:OntologyClass stalk A cardinal organ part (PO:0025001) that is elongated and sub-cylindrical to cylindrical and supports another cardinal organ part. go-plus.json tallo de alto orden (secundario, terciario, etc) (Spanish, exact)|stipe (related)|柄 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025066 CHEBI:77019 biolink:ChemicalSubstance EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77019 CHEBI:28005 biolink:ChemicalSubstance cyclohex-1-ene-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28005 CHEBI:28001 biolink:ChemicalSubstance vancomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28001 CHEBI:28000 biolink:ChemicalSubstance N-acetyl-D-hexosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28000 chebi_ph7_3 UBERON:0006003 biolink:AnatomicalEntity integumentary adnexa Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. go-plus.json skin adnexa|skin appendage|body hair or bristle|skin adnexal structure|adnexae cutis http://purl.obolibrary.org/obo/UBERON_0006003 UBERON:0006002 biolink:AnatomicalEntity vitelline artery The paired arteries that carry blood to the yolk sac from the dorsal aorta go-plus.json http://purl.obolibrary.org/obo/UBERON_0006002 CHEBI:422 biolink:ChemicalSubstance (S)-lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_422 UBERON:0006009 biolink:AnatomicalEntity cusp of cardiac valve The part of the heart valves that serves to seal the heart valves when closed. There are three cusps for each valve except for the mitral valve, which has only two (hence its alternate name, 'bicuspid valve'). 'Nodules' are located at the tip of the valve, to form a tighter seal[WP]. go-plus.json cardiac valve cusp|semilunar valvule|cardial valve cusp|cardiac valvule|cardiac valvular cusp http://purl.obolibrary.org/obo/UBERON_0006009 UBERON:0006008 biolink:AnatomicalEntity fibrous ring of heart A ring of ribrous tissue that surrounds the atrioventricular and arterial orifices go-plus.json annulus fibrosus cordis|fibrous ring of heart|coronary tendon|Lower's ring|aortic annulus|atrioventricular ring|anulus fibrosus cordis|anulus fibrosus of heart http://purl.obolibrary.org/obo/UBERON_0006008 CHEBI:77011 biolink:ChemicalSubstance 5-O-mycaminosyltylonolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_77011 PO:0025059 biolink:OntologyClass portion of ground tissue Any portion of plant tissue (PO:0009007) other than epidermis (PO:0005679) or vascular tissue (PO:0009015). go-plus.json 基本組織の一部 (Japanese, exact)|porción del tejido fundamental (Spanish, exact)|fundamental tissue (exact) http://purl.obolibrary.org/obo/PO_0025059 CHEBI:77016 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77016 chebi_ph7_3 CHEBI:77015 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77015 chebi_ph7_3 CHEBI:28018 biolink:ChemicalSubstance 3,3',4',5,7-pentahydroxy-8-methoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28018 CHEBI:28017 biolink:ChemicalSubstance starch go-plus.json http://purl.obolibrary.org/obo/CHEBI_28017 CHEBI:28013 biolink:ChemicalSubstance beta-D-fructofuranose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28013 CHEBI:28011 biolink:ChemicalSubstance 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28011 CHEBI:77021 biolink:ChemicalSubstance cellobionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77021 CHEBI:77020 biolink:ChemicalSubstance EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77020 CHEBI:77024 biolink:ChemicalSubstance EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77024 PO:0001097 biolink:OntologyClass plant zygote stage A sporophyte development stage (PO:0007134) that occurs during the interval between fertilization and the first cell division of the plant zygote (PO:0000423). go-plus.json zygote in Arabidopsis (related)|one cell stage (related)|zygote stage (broad)|embryo stage EM1 (related) http://purl.obolibrary.org/obo/PO_0001097 CHEBI:77029 biolink:ChemicalSubstance 3-(5-oxoisoxazolin-2-yl)-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77029 CHEBI:77027 biolink:ChemicalSubstance 7-deoxyloganetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77027 CHEBI:77031 biolink:ChemicalSubstance (2S,3S)-beta-methylphenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77031 CHEBI:77030 biolink:ChemicalSubstance 3-(5-oxoisoxazolin-4-yl)-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77030 CHEBI:77036 biolink:ChemicalSubstance A41030A go-plus.json http://purl.obolibrary.org/obo/CHEBI_77036 CHEBI:77035 biolink:ChemicalSubstance expectorant go-plus.json http://purl.obolibrary.org/obo/CHEBI_77035 CHEBI:77034 biolink:ChemicalSubstance mucolytic go-plus.json http://purl.obolibrary.org/obo/CHEBI_77034 CHEBI:18697 biolink:ChemicalSubstance (R)-pantoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18697 CHEBI:77033 biolink:ChemicalSubstance 14-hydroxymyristate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77033 chebi_ph7_3 PO:0001083 biolink:OntologyClass inflorescence development stage A reproductive shoot system development stage (PO:0025530) that has as primary participant a inflorescence (PO:0009049). go-plus.json panicle development (related) http://purl.obolibrary.org/obo/PO_0001083 CHEBI:77039 biolink:ChemicalSubstance (2E)-tetradecenedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77039 chebi_ph7_3 CHEBI:77038 biolink:ChemicalSubstance (3S)-hydroxytetradecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77038 chebi_ph7_3 CHEBI:77037 biolink:ChemicalSubstance N,N-dimethyl-L-alanyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_77037 chebi_ph7_3 PO:0025034 biolink:OntologyClass leaf A phyllome (PO:0006001) that is not associated with a reproductive structure. go-plus.json hoja (Spanish, exact)|葉 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025034 PO:0025030 biolink:OntologyClass ground tissue cell A native plant cell (PO:0025606) that is part of a portion of ground tissue (PO:0025059). go-plus.json 基本組織細胞 (Japanese, exact)|célula del tejido fundamental (Spanish, exact)|fundamental tissue cell (exact) http://purl.obolibrary.org/obo/PO_0025030 CHEBI:43619 biolink:ChemicalSubstance icosane go-plus.json http://purl.obolibrary.org/obo/CHEBI_43619 chebi_ph7_3 CHEBI:43615 biolink:ChemicalSubstance 2H-imidazol-4-ylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43615 CHEBI:77042 biolink:ChemicalSubstance N,N-dimethyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77042 CHEBI:77041 biolink:ChemicalSubstance 3-oxotetradecanedioyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77041 chebi_ph7_3 CHEBI:77047 biolink:ChemicalSubstance tylosin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77047 chebi_ph7_3 CHEBI:77046 biolink:ChemicalSubstance isopimarane go-plus.json http://purl.obolibrary.org/obo/CHEBI_77046 chebi_ph7_3 PO:0025029 biolink:OntologyClass shoot axis A plant axis (PO:0025004) that is part of a shoot system (PO:0009006). go-plus.json caullome (exact)|shoot (related)|eje del epiblasto (epiblastema) (Spanish, exact)|シュート軸 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025029 PO:0025028 biolink:OntologyClass embryo plant cell A native plant cell (PO:0025606) that is part of a plant embryo (PO:0009009). go-plus.json embryo cell (broad)|embryonic plant cell (exact)|胚性植物細胞 (Japanese, exact)|célula embriónica vegetal (Spanish, exact)|embryonic cell (broad) http://purl.obolibrary.org/obo/PO_0025028 PO:0025026 biolink:OntologyClass embryo sac cell A native plant cell (PO:0025606) that is part of an embryo sac (PO:0025074). go-plus.json embryo sac cell (related)|célula megagametofítica (Spanish, exact)|胚嚢細胞 (Japanese, exact)|megagametophytic cell (exact) http://purl.obolibrary.org/obo/PO_0025026 CHEBI:77049 biolink:ChemicalSubstance (R,R)-pavine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77049 PO:0025025 biolink:OntologyClass root system A collective plant organ structure (PO:0025007) that produces root meristems (PO:0006085), the plant structures (PO:0009011) that arise from them and the parts thereof. go-plus.json 根系 (Japanese, exact)|sistema de raíz (Spanish, exact)|root (broad) http://purl.obolibrary.org/obo/PO_0025025 CHEBI:77048 biolink:ChemicalSubstance pavine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77048 CHEBI:137899 biolink:ChemicalSubstance phosphatidic acid 44:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137899 CHEBI:137898 biolink:ChemicalSubstance phosphatidic acid 43:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137898 CHEBI:53082 biolink:ChemicalSubstance prostaglandin H2 1-ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_53082 chebi_ph7_3 CHEBI:137897 biolink:ChemicalSubstance phosphatidic acid 41:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137897 CHEBI:137896 biolink:ChemicalSubstance phosphatidic acid 41:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137896 CHEBI:53081 biolink:ChemicalSubstance prostaglandin F2alpha 1-ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_53081 chebi_ph7_3 CHEBI:137891 biolink:ChemicalSubstance phosphatidic acid 39:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137891 CHEBI:137890 biolink:ChemicalSubstance phosphatidic acid 38:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137890 CHEBI:137895 biolink:ChemicalSubstance phosphatidic acid 41:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137895 CHEBI:137894 biolink:ChemicalSubstance phosphatidic acid 41:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137894 CHEBI:137893 biolink:ChemicalSubstance phosphatidic acid 40:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137893 CHEBI:137892 biolink:ChemicalSubstance phosphatidic acid 39:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137892 CHEBI:53072 biolink:ChemicalSubstance beta-L-galactose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53072 CHEBI:53071 biolink:ChemicalSubstance L-galactonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53071 chebi_ph7_3 CHEBI:53079 biolink:ChemicalSubstance lysine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_53079 GO:0004587 biolink:MolecularActivity ornithine-oxo-acid transaminase activity Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid. Reactome:R-HSA-70654|MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN|EC:2.6.1.13|RHEA:13877|Reactome:R-HSA-70666 go-plus.json L-ornithine:alpha-ketoglutarate delta-aminotransferase activity|ornithine 5-aminotransferase activity|L-ornithine 5-aminotransferase activity|ornithine aminotransferase activity|L-ornithine aminotransferase activity|L-ornithine:2-oxo-acid aminotransferase activity|ornithine--alpha-ketoglutarate aminotransferase activity|ornithine--keto acid transaminase activity|ornithine delta-transaminase activity|GabT|ornithine-oxo-acid aminotransferase activity|ornithine--oxo acid aminotransferase activity|ornithine ketoacid aminotransferase activity|ornithine:alpha-oxoglutarate transaminase activity|ornithine--oxo-acid transaminase activity|ornithine transaminase activity|OAT|ornithine--2-oxoacid aminotransferase activity|ornithine--keto acid aminotransferase activity|ornithine--ketoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0004587 GO:0004586 biolink:MolecularActivity ornithine decarboxylase activity Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine. EC:4.1.1.17|Reactome:R-HSA-70692|RHEA:22964|MetaCyc:ORNDECARBOX-RXN|KEGG_REACTION:R00670 go-plus.json SpeC|L-ornithine carboxy-lyase (putrescine-forming)|L-ornithine carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0004586 GO:0004589 biolink:MolecularActivity orotate reductase (NADH) activity Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate. MetaCyc:OROTATE-REDUCTASE-NADH-RXN|KEGG_REACTION:R01869|EC:1.3.1.14|RHEA:13513 go-plus.json (S)-dihydroorotate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004589 GO:0004588 biolink:MolecularActivity orotate phosphoribosyltransferase activity Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. Reactome:R-HSA-73567|MetaCyc:OROPRIBTRANS-RXN|EC:2.4.2.10|RHEA:10380 go-plus.json orotidylic acid phosphorylase activity|orotidine-5'-phosphate pyrophosphorylase activity|orotidine-5'-phosphate diphosphorylase activity|orotidylic phosphorylase activity|orotidine monophosphate pyrophosphorylase activity|orotic acid phosphoribosyltransferase activity|orotidylate phosphoribosyltransferase activity|orotate phosphoribosyl pyrophosphate transferase activity|orotidine phosphoribosyltransferase activity|orotidylate pyrophosphorylase activity|OPRT activity|orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity|orotidine 5'-monophosphate pyrophosphorylase activity|OPRTase activity|orotidylic acid pyrophosphorylase activity|orotidylic pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0004588 GO:0004583 biolink:MolecularActivity dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide. Reactome:R-HSA-446194|MetaCyc:RXN-5472|Reactome:R-HSA-4724330|Reactome:R-HSA-4724291|Reactome:R-HSA-446202|Reactome:R-HSA-446189 go-plus.json http://purl.obolibrary.org/obo/GO_0004583 GO:0004582 biolink:MolecularActivity dolichyl-phosphate beta-D-mannosyltransferase activity Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate. Reactome:R-HSA-4719375|Reactome:R-HSA-4719354|EC:2.4.1.83|RHEA:21184|Reactome:R-HSA-162721|Reactome:R-HSA-4717406|MetaCyc:2.4.1.83-RXN go-plus.json DPM synthase activity|dolichyl-phosphate mannose synthase activity|dolichyl phosphate mannosyltransferase activity|guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity|mannosylphosphodolichol synthase activity|dolichol-phosphate-mannose synthase activity|GDPMan:DolP mannosyltransferase activity|GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity|GDP-mannose-dolichol phosphate mannosyltransferase activity|dolichol phosphate mannose synthase activity|GDPmannose-dolichylmonophosphate mannosyltransferase activity|dolichyl-phospho-mannose synthase activity|GDPmannose:dolichyl-phosphate mannosyltransferase activity|dolichyl mannosyl phosphate synthase activity|dolichol-phosphate mannose synthase activity|mannosylphosphoryldolichol synthase activity|dolichol-phosphate mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0004582 GO:0004585 biolink:MolecularActivity ornithine carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. MetaCyc:RXN-13482|Reactome:R-HSA-70560|RHEA:19513|EC:2.1.3.3|MetaCyc:ORNCARBAMTRANSFER-RXN go-plus.json L-ornithine carbamyltransferase activity|ornithine carbamyltransferase activity|carbamylphosphate-ornithine transcarbamylase activity|ornithine transcarbamylase activity|L-ornithine transcarbamylase activity|L-ornithine carbamoyltransferase activity|carbamoyl-phosphate:L-ornithine carbamoyltransferase activity|OTCase activity|citrulline phosphorylase activity|OTC activity http://purl.obolibrary.org/obo/GO_0004585 GO:0004584 biolink:MolecularActivity obsolete dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity OBSOLETE. Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide. MetaCyc:2.4.1.130-RXN|EC:2.4.1.130 go-plus.json dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity|dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity|oligomannosylsynthase activity http://purl.obolibrary.org/obo/GO_0004584 GO:0004581 biolink:MolecularActivity dolichyl-phosphate beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate. MetaCyc:2.4.1.117-RXN|RHEA:15401|EC:2.4.1.117|Reactome:R-HSA-446214 go-plus.json UDP-glucose:dolichol phosphate glucosyltransferase activity|uridine diphosphoglucose-dolichol glucosyltransferase activity|polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity|UDP-glucose:dolicholphosphoryl glucosyltransferase activity|UDP-glucose dolichyl-phosphate glucosyltransferase activity|UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity|UDP-glucose:dolichyl monophosphate glucosyltransferase activity|UDP-glucose:dolichyl phosphate glucosyltransferase activity|UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0004581 GO:0004580 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004580 GO:0004598 biolink:MolecularActivity peptidylamidoglycolate lyase activity Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate. EC:4.3.2.5|RHEA:20924|MetaCyc:PEPTIDYLAMIDOGLYCOLATE-LYASE-RXN go-plus.json HGAD|peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity|PAL|peptidylamidoglycolate peptidylamide-lyase activity|peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)|PGL|alpha-hydroxyglycine amidating dealkylase activity http://purl.obolibrary.org/obo/GO_0004598 GO:0004597 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004597 GO:0004594 biolink:MolecularActivity pantothenate kinase activity Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate. RHEA:16373|Reactome:R-HSA-199203|Reactome:R-HSA-196857|MetaCyc:PANTOTHENATE-KIN-RXN|EC:2.7.1.33 go-plus.json ATP:(R)-pantothenate 4'-phosphotransferase activity|pantothenate kinase (phosphorylating) activity|pantothenic acid kinase activity|D-pantothenate kinase activity|ATP:pantothenate 4'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004594 GO:0004593 biolink:MolecularActivity pantothenase activity Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine. RHEA:12448|EC:3.5.1.22|MetaCyc:PANTOTHENASE-RXN|KEGG_REACTION:R02474 go-plus.json pantothenate amidohydrolase activity|pantothenate hydrolase activity|(R)-pantothenate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0004593 GO:0004596 biolink:MolecularActivity peptide alpha-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein. Reactome:R-HSA-6814090|MetaCyc:PEPTIDE-ALPHA-N-ACETYLTRANSFERASE-RXN go-plus.json nalpha-acetyltransferase activity|amino-terminal amino acid-acetylating enzyme activity|acetyl-CoA:peptide alpha-N-acetyltransferase activity|peptide acetyltransferase activity|protein N-terminal acetyltransferase activity|beta-endorphin acetyltransferase activity|N(alpha)-acetyltransferase activity|acetyl-CoA:peptide nalpha-acetyltransferase activity|NAT activity http://purl.obolibrary.org/obo/GO_0004596 GO:0004595 biolink:MolecularActivity pantetheine-phosphate adenylyltransferase activity Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate. Reactome:R-HSA-196754|EC:2.7.7.3|MetaCyc:PANTEPADENYLYLTRAN-RXN|KEGG_REACTION:R03035|RHEA:19801 go-plus.json ATP:pantetheine-4'-phosphate adenylyltransferase activity|ATP:pantetheine-phosphate adenylyltransferase activity|3'-dephospho-CoA pyrophosphorylase activity|pantetheine phosphate adenylyltransferase activity|PPAT activity|phosphopantetheine adenylyltransferase activity|dephospho-coenzyme A pyrophosphorylase activity|dephospho-CoA pyrophosphorylase activity|dephospho-CoA diphosphorylase activity http://purl.obolibrary.org/obo/GO_0004595 GO:0004590 biolink:MolecularActivity orotidine-5'-phosphate decarboxylase activity Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP. MetaCyc:OROTPDECARB-RXN|Reactome:R-HSA-73564|KEGG_REACTION:R00965|EC:4.1.1.23|RHEA:11596 go-plus.json ODCase activity|orotodylate decarboxylase activity|orotic decarboxylase activity|orotate monophosphate decarboxylase activity|orotidine 5'-phosphate decarboxylase activity|orotidine-5'-phosphate carboxy-lyase activity|orotate decarboxylase activity|OMP-DC|orotidylic acid decarboxylase activity|orotidine-5'-monophosphate decarboxylase activity|orotidylic decarboxylase activity|orotidine-5'-phosphate carboxy-lyase (UMP-forming)|OMP decarboxylase activity|UMP synthase activity|uridine 5'-monophosphate synthase activity|orotidine monophosphate decarboxylase activity|OMPdcase activity|orotidine phosphate decarboxylase activity http://purl.obolibrary.org/obo/GO_0004590 GO:0004592 biolink:MolecularActivity pantoate-beta-alanine ligase activity Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate. MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN|RHEA:10912|EC:6.3.2.1 go-plus.json pantoic-activating enzyme activity|pantoate-activating enzyme activity|(R)-pantoate:beta-alanine ligase (AMP-forming)|pantothenate synthetase activity|D-pantoate:beta-alanine ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0004592 GO:0004591 biolink:MolecularActivity oxoglutarate dehydrogenase (succinyl-transferring) activity Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2. EC:1.2.4.2|MetaCyc:2OXOGLUTDECARB-RXN|RHEA:12188 go-plus.json 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity|2-oxoglutarate: lipoate oxidoreductase activity|ketoglutaric dehydrogenase activity|OGDC activity|alpha-oxoglutarate dehydrogenase activity|2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)|alpha-ketoglutaric acid dehydrogenase activity|oxoglutarate decarboxylase activity|2-ketoglutarate dehydrogenase activity|AKGDH activity|oxoglutarate dehydrogenase (lipoamide) activity|2-oxoglutarate dehydrogenase activity|alpha-ketoglutaric dehydrogenase activity|oxoglutarate dehydrogenase activity|alpha-ketoglutarate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004591 CHEBI:137886 biolink:ChemicalSubstance 3alpha,7beta-dihydroxy-12-oxo-5beta-cholanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137886 chebi_ph7_3 CHEBI:137880 biolink:ChemicalSubstance ursocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137880 chebi_ph7_3 CHEBI:137882 biolink:ChemicalSubstance 7beta-hydroxy-3,12-dioxo-5beta-cholanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137882 chebi_ph7_3 CHEBI:137881 biolink:ChemicalSubstance 3,7,12-trioxo-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137881 chebi_ph7_3 GO:0004569 biolink:MolecularActivity glycoprotein endo-alpha-1,2-mannosidase activity Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane. EC:3.2.1.130|RHEA:54824|Reactome:R-HSA-964759|MetaCyc:3.2.1.130-RXN go-plus.json glycoprotein glucosylmannohydrolase activity|glucosyl mannosidase activity|endomannosidase activity|glucosylmannosidase activity|endo-alpha-mannosidase activity http://purl.obolibrary.org/obo/GO_0004569 GO:0004568 biolink:MolecularActivity chitinase activity Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. EC:3.2.1.14|Reactome:R-HSA-6786421|MetaCyc:3.2.1.14-RXN go-plus.json poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity|poly-beta-glucosaminidase activity|1,4-beta-poly-N-acetylglucosaminidase activity|chitodextrinase activity|beta-1,4-poly-N-acetyl glucosamidinase activity http://purl.obolibrary.org/obo/GO_0004568 GO:0004565 biolink:MolecularActivity beta-galactosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides. MetaCyc:BGALACT-PWY|Reactome:R-HSA-9036061|EC:3.2.1.23|Reactome:R-HSA-2265534|Reactome:R-HSA-1630306|Reactome:R-HSA-1605624|Reactome:R-HSA-1793217|MetaCyc:3.2.1.23-RXN|Reactome:R-HSA-1606312|Reactome:R-HSA-2090079 go-plus.json exo-(1->4)-beta-D-galactanase activity|beta-lactosidase activity|hydrolact|S 2107|sumiklat|beta-D-galactanase activity|trilactase activity|maxilact|oryzatym|beta-D-galactoside galactohydrolase activity|beta-D-lactosidase activity|lactozym|lactose hydrolysis http://purl.obolibrary.org/obo/GO_0004565 GO:0004564 biolink:MolecularActivity beta-fructofuranosidase activity Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside. MetaCyc:RXN-9985|EC:3.2.1.26 go-plus.json beta-D-fructofuranoside fructohydrolase activity|beta-fructosidase activity|alkaline invertase activity|maxinvert L 1000 activity|beta-h-fructosidase activity|acid invertase activity|invertin activity|invertase activity|glucosucrase activity|saccharase activity|fructosylinvertase activity http://purl.obolibrary.org/obo/GO_0004564 GO:0004567 biolink:MolecularActivity beta-mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. Reactome:R-HSA-8853710|EC:3.2.1.25|MetaCyc:3.2.1.25-RXN go-plus.json beta-D-mannoside mannohydrolase activity|mannanase activity|beta-D-mannosidase activity|exo-beta-D-mannanase activity|mannase activity|beta-mannoside mannohydrolase activity http://purl.obolibrary.org/obo/GO_0004567 GO:0004566 biolink:MolecularActivity beta-glucuronidase activity Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate. Reactome:R-HSA-2162226|Reactome:R-HSA-9036070|MetaCyc:BETA-GLUCURONID-RXN|EC:3.2.1.31|Reactome:R-HSA-9036068|RHEA:17633|Reactome:R-HSA-2162227|Reactome:R-HSA-2318373|Reactome:R-HSA-1678854 go-plus.json exo-beta-D-glucuronidase activity|beta-glucuronide glucuronohydrolase activity|ketodase activity|glucuronidase activity|beta-D-glucuronoside glucuronosohydrolase activity http://purl.obolibrary.org/obo/GO_0004566 GO:0004561 biolink:MolecularActivity alpha-N-acetylglucosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. EC:3.2.1.50|Reactome:R-HSA-1678742|Reactome:R-HSA-9036052|Reactome:R-HSA-2090038|Reactome:R-HSA-2263496|MetaCyc:3.2.1.50-RXN go-plus.json alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity|alpha-D-2-acetamido-2-deoxyglucosidase activity|N-acetyl-alpha-glucosaminidase activity|alpha-acetylglucosaminidase activity|N-acetyl-alpha-D-glucosaminidase activity|NAG activity http://purl.obolibrary.org/obo/GO_0004561 GO:0004560 biolink:MolecularActivity alpha-L-fucosidase activity Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose. EC:3.2.1.51|RHEA:12288|Reactome:R-HSA-5693807|MetaCyc:ALPHA-L-FUCOSIDASE-RXN go-plus.json alpha-L-fucoside fucohydrolase activity|alpha-fucosidase activity http://purl.obolibrary.org/obo/GO_0004560 GO:0004563 biolink:MolecularActivity beta-N-acetylhexosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Reactome:R-HSA-3656259|Reactome:R-HSA-1605595|Reactome:R-HSA-9638078|Reactome:R-HSA-2105001|Reactome:R-HSA-1605632|Reactome:R-HSA-9638075|Reactome:R-HSA-9035982|Reactome:R-HSA-9638076|EC:3.2.1.52|Reactome:R-HSA-1638053|Reactome:R-HSA-9035978|Reactome:R-HSA-9035983|Reactome:R-HSA-9035976|Reactome:R-HSA-2162225|MetaCyc:3.2.1.52-RXN|Reactome:R-HSA-3662344 go-plus.json N-acetyl-beta-hexosaminidase activity|N-acetyl-beta-glucosaminidase activity|beta-N-acetyl-D-hexosaminidase activity|beta-acetylhexosaminidinase activity|N-acetyl-beta-D-hexosaminidase activity|beta-hexosaminidase activity|beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity|hexosaminidase A|beta-acetylaminodeoxyhexosidase activity|N-acetylhexosaminidase activity|beta-D-hexosaminidase activity|beta-D-N-acetylhexosaminidase activity http://purl.obolibrary.org/obo/GO_0004563 GO:0004562 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004562 CHEBI:28087 biolink:ChemicalSubstance glycogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_28087 CHEBI:28089 biolink:ChemicalSubstance N-hydroxytyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28089 CHEBI:28088 biolink:ChemicalSubstance genistein go-plus.json http://purl.obolibrary.org/obo/CHEBI_28088 CHEBI:28093 biolink:ChemicalSubstance borneol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28093 chebi_ph7_3 CHEBI:53041 biolink:ChemicalSubstance dodecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53041 CHEBI:28096 biolink:ChemicalSubstance S-methyl-5-thio-D-ribulose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28096 CHEBI:137852 biolink:ChemicalSubstance phosphatidylcholine 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137852 chebi_ph7_3 CHEBI:53040 biolink:ChemicalSubstance tridecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53040 CHEBI:137856 biolink:ChemicalSubstance 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronide] go-plus.json http://purl.obolibrary.org/obo/CHEBI_137856 CHEBI:53047 biolink:ChemicalSubstance hexaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53047 CHEBI:53046 biolink:ChemicalSubstance heptaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53046 CHEBI:53048 biolink:ChemicalSubstance pentaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53048 NCBITaxon:1489341 biolink:OrganismalEntity Osteoglossocephalai go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1489341 CHEBI:53043 biolink:ChemicalSubstance decaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53043 CHEBI:53042 biolink:ChemicalSubstance undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53042 CHEBI:53045 biolink:ChemicalSubstance octaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53045 CHEBI:53044 biolink:ChemicalSubstance nonaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53044 GO:0004579 biolink:MolecularActivity dolichyl-diphosphooligosaccharide-protein glycotransferase activity Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine. RHEA:22980|EC:2.4.99.18|Reactome:R-HSA-9694793|Reactome:R-HSA-446209|MetaCyc:2.4.1.119-RXN go-plus.json dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity|oligomannosyltransferase activity|asparagine N-glycosyltransferase activity|dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity|dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity|dolichyldiphosphooligosaccharide-protein glycosyltransferase activity|dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity|dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity http://purl.obolibrary.org/obo/GO_0004579 GO:0004576 biolink:MolecularActivity oligosaccharyl transferase activity Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid. go-plus.json oligosaccharide transferase activity http://purl.obolibrary.org/obo/GO_0004576 GO:0004575 biolink:MolecularActivity sucrose alpha-glucosidase activity Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose. Reactome:R-HSA-189069|Reactome:R-HSA-5659926|MetaCyc:RXN-1461|EC:3.2.1.48|KEGG_REACTION:R00802|RHEA:33795 go-plus.json sucrose alpha-D-glucohydrolase activity|sucrase-isomaltase activity|sucrase(invertase)|sucrase activity|sucrose hydrolysis|intestinal sucrase activity|alpha-D-glucopyranosyl beta-D-fructofuranoside hydrolysis|sucrose-alpha-D-glucohydrolase activity|beta-D-fructofuranosyl alpha-D-glucopyranoside hydrolysis|sucrose alpha-glucohydrolase activity http://purl.obolibrary.org/obo/GO_0004575 CHEBI:53039 biolink:ChemicalSubstance tetradecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53039 GO:0004578 biolink:MolecularActivity chitobiosyldiphosphodolichol beta-mannosyltransferase activity Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol. Reactome:R-HSA-446218|MetaCyc:2.4.1.142-RXN|Reactome:R-HSA-4549382|EC:2.4.1.142|RHEA:13865 go-plus.json guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity|GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity|GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0004578 GO:0004577 biolink:MolecularActivity N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol. MetaCyc:2.4.1.141-RXN|RHEA:23380|EC:2.4.1.141|Reactome:R-HSA-446207|Reactome:R-HSA-5633241 go-plus.json UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity|N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity|uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0004577 GO:0004572 biolink:MolecularActivity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3). MetaCyc:3.2.1.114-RXN|EC:3.2.1.114|RHEA:56052|Reactome:R-HSA-975814 go-plus.json ManII activity|GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity|mannosidase II activity|alpha-(1,3/6)-mannosidase activity|alpha-D-mannosidase II|exo-1,3-1,6-alpha-mannosidase activity|1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-mannosidase II|mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity|mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity|Golgi alpha-mannosidase II|mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity http://purl.obolibrary.org/obo/GO_0004572 GO:0004571 biolink:MolecularActivity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide. Reactome:R-HSA-901039|MetaCyc:3.2.1.113-RXN|KEGG_REACTION:R05982|Reactome:R-HSA-901024|EC:3.2.1.113|Reactome:R-HSA-9696807|Reactome:R-HSA-9036012|Reactome:R-HSA-9036011|Reactome:R-HSA-6782685|Reactome:R-HSA-964825|Reactome:R-HSA-964737|Reactome:R-HSA-964830|Reactome:R-HSA-901036|Reactome:R-HSA-9036008|KEGG_REACTION:R06722|Reactome:R-HSA-901074|Reactome:R-HSA-4793949 go-plus.json 1,2-alpha-mannosidase|glycoprotein processing mannosidase I|exo-alpha-1,2-mannanase activity|1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|mannose-9 processing alpha-mannosidase activity|ManI activity|mannosidase 1A activity|mannosidase I|mannosidase 1B activity|Man9-mannosidase activity|man9-mannosidase activity http://purl.obolibrary.org/obo/GO_0004571 GO:0004574 biolink:MolecularActivity oligo-1,6-glucosidase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose. MetaCyc:3.2.1.10-RXN|EC:3.2.1.10 go-plus.json exo-oligo-1,6-glucosidase activity|dextrin 6-glucanohydrolase activity|dextrin 6alpha-glucanohydrolase activity|oligosaccharide alpha-1,6-glucohydrolase activity|alpha-limit dextrinase activity|isomaltase activity|oligosaccharide alpha-1,6-glucosidase activity|alpha-methylglucosidase activity|limit dextrinase|sucrase-isomaltase activity http://purl.obolibrary.org/obo/GO_0004574 GO:0004573 biolink:MolecularActivity mannosyl-oligosaccharide glucosidase activity Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2). EC:3.2.1.106|Reactome:R-HSA-9694364|RHEA:55988|Reactome:R-HSA-532678|Reactome:R-HSA-4793947|MetaCyc:3.2.1.106-RXN go-plus.json Glc3Man9NAc2 oligosaccharide glucosidase activity|mannosyl-oligosaccharide glucohydrolase activity|trimming glucosidase I|processing A-glucosidase I activity|mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity http://purl.obolibrary.org/obo/GO_0004573 CHEBI:28098 biolink:ChemicalSubstance kanamycin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_28098 CHEBI:28097 biolink:ChemicalSubstance chlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28097 chebi_ph7_3 CHEBI:28099 biolink:ChemicalSubstance prostaglandin B2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28099 CHEBI:53030 biolink:ChemicalSubstance oxysterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_53030 GO:0004549 biolink:MolecularActivity tRNA-specific ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules. Reactome:R-HSA-5696813|Reactome:R-HSA-6785722|Reactome:R-HSA-6786854|Reactome:R-HSA-5696815 go-plus.json tRNA-specific RNase activity http://purl.obolibrary.org/obo/GO_0004549 CHEBI:53028 biolink:ChemicalSubstance 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53028 CHEBI:28068 biolink:ChemicalSubstance all-trans-zeta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28068 chebi_ph7_3 GO:0004540 biolink:MolecularActivity ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0004540 CHEBI:28064 biolink:ChemicalSubstance cyanidin 3-O-rutinoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28064 CHEBI:28066 biolink:ChemicalSubstance gentiobiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28066 chebi_ph7_3 CHEBI:28072 biolink:ChemicalSubstance guanosine 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28072 CHEBI:28071 biolink:ChemicalSubstance (indol-3-ylacetyl)-myo-inositol 3-L-arabinoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28071 chebi_ph7_3 CHEBI:28073 biolink:ChemicalSubstance chromium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_28073 chebi_ph7_3 CHEBI:137837 biolink:ChemicalSubstance 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137837 CHEBI:137836 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(36:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137836 CHEBI:28070 biolink:ChemicalSubstance uridine 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28070 CHEBI:53025 biolink:ChemicalSubstance L-galactose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53025 GO:0004558 biolink:MolecularActivity alpha-1,4-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. Reactome:R-HSA-5659899|EC:3.2.1.20|Reactome:R-HSA-191116|MetaCyc:MALTODEXGLUCOSID-RXN|Reactome:R-HSA-189102|Reactome:R-HSA-191108|Reactome:R-HSA-5659922|Reactome:R-HSA-5659861|Reactome:R-HSA-189053|Reactome:R-HSA-5659879|Reactome:R-HSA-191101 go-plus.json alpha-1,4-glucosidase activity|glucosidoinvertase activity|alpha-D-glucoside glucohydrolase activity|glucoinvertase activity|alpha-glucosidase II|glucosidosucrase activity|alpha-D-glucosidase activity|alpha-glucopyranosidase activity|lysosomal alpha-glucosidase activity|maltase-glucoamylase activity|acid maltase activity|alpha-glucoside hydrolase activity http://purl.obolibrary.org/obo/GO_0004558 GO:0004557 biolink:MolecularActivity alpha-galactosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase. MetaCyc:ALPHAGALACTOSID-RXN|RHEA:28663|Reactome:R-HSA-1605736|EC:3.2.1.22 go-plus.json alpha-D-galactosidase activity|alpha-galactosidase A|alpha-galactoside galactohydrolase activity|melibiase activity|alpha-D-galactoside galactohydrolase activity http://purl.obolibrary.org/obo/GO_0004557 GO:0004559 biolink:MolecularActivity alpha-mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Reactome:R-HSA-6799545|MetaCyc:3.2.1.24-RXN|Reactome:R-HSA-8853686|Reactome:R-HSA-9694656|EC:3.2.1.24 go-plus.json exo-alpha-mannosidase activity|alpha-D-mannopyranosidase activity|alpha-D-mannoside mannohydrolase activity|p-nitrophenyl-alpha-mannosidase activity|1,2-alpha-D-mannosidase activity|alpha-D-mannosidase activity|1,2-alpha-mannosidase http://purl.obolibrary.org/obo/GO_0004559 GO:0004553 biolink:MolecularActivity hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond. Reactome:R-HSA-9661820|EC:3.2.1.-|Reactome:R-HSA-5694563|Reactome:R-HSA-6786652 go-plus.json O-glucosyl hydrolase activity http://purl.obolibrary.org/obo/GO_0004553 GO:0004556 biolink:MolecularActivity alpha-amylase activity Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units. Reactome:R-HSA-188979|MetaCyc:RXN-1825|EC:3.2.1.1|MetaCyc:RXN-1823|MetaCyc:ALPHA-AMYL-RXN|Reactome:R-HSA-191114 go-plus.json alpha amylase activity|1,4-alpha-D-glucan glucanohydrolase activity|endoamylase activity|taka-amylase A|glycogenase activity http://purl.obolibrary.org/obo/GO_0004556 GO:0004555 biolink:MolecularActivity alpha,alpha-trehalase activity Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose. Reactome:R-HSA-188985|MetaCyc:TREHALA-RXN|EC:3.2.1.28|RHEA:20868 go-plus.json alpha,alpha-trehalose glucohydrolase activity http://purl.obolibrary.org/obo/GO_0004555 GO:0004550 biolink:MolecularActivity nucleoside diphosphate kinase activity Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. Reactome:R-HSA-2162096|Reactome:R-HSA-482812|Reactome:R-HSA-6806877|MetaCyc:NUCLEOSIDE-DIP-KIN-RXN|Reactome:R-HSA-482619|Reactome:R-HSA-482621|Reactome:R-HSA-482804|EC:2.7.4.6 go-plus.json UDP kinase activity|uridine diphosphate kinase activity|nucleoside-diphosphate kinase activity|nucleoside diphosphate (UDP) kinase activity|nucleoside diphosphokinase activity|ATP:nucleoside-diphosphate phosphotransferase activity|NDK activity|nucleotide phosphate kinase activity|nucleoside 5'-diphosphate kinase activity|nucleoside 5'-diphosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004550 GO:0004552 biolink:MolecularActivity octanol dehydrogenase activity Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH. RHEA:24620|MetaCyc:OCTANOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02878|EC:1.1.1.73 go-plus.json 1-octanol dehydrogenase activity|octanol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004552 GO:0004551 biolink:MolecularActivity nucleotide diphosphatase activity Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides. Reactome:R-HSA-196955|MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN|EC:3.6.1.9 go-plus.json dinucleotide nucleotidohydrolase activity|nucleotide pyrophosphatase activity|nucleotide-sugar pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0004551 CHEBI:137849 biolink:ChemicalSubstance phosphatidic acid 32:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137849 CHEBI:28077 biolink:ChemicalSubstance rifampicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28077 CHEBI:28082 biolink:ChemicalSubstance 5alpha-cholestane-3beta,5,6beta-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28082 chebi_ph7_3 CHEBI:7815 biolink:ChemicalSubstance oxalosuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7815 CHEBI:28080 biolink:ChemicalSubstance (2Z,4E)-2-hydroxymuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_28080 chebi_ph7_3 CHEBI:53013 biolink:ChemicalSubstance 3'-CMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_53013 CHEBI:53010 biolink:ChemicalSubstance nucleoside 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53010 CHEBI:53012 biolink:ChemicalSubstance xanthosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53012 GO:0102991 biolink:MolecularActivity myristoyl-CoA hydrolase activity Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A. EC:3.1.2.2|MetaCyc:RXN-9626|RHEA:40119 go-plus.json http://purl.obolibrary.org/obo/GO_0102991 GO:0102990 biolink:MolecularActivity 5-n-alk(en)ylresorcinol O-methyltransferase activity Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine. RHEA:26325|MetaCyc:RXN-9619 go-plus.json http://purl.obolibrary.org/obo/GO_0102990 GO:0102993 biolink:MolecularActivity linolenate delta15 desaturase activity Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor. MetaCyc:RXN-9667|RHEA:46408 go-plus.json http://purl.obolibrary.org/obo/GO_0102993 GO:0102992 biolink:MolecularActivity 2-methylbutyronitrile hydroxylase activity Catalysis of the reaction: H+ + 2-methylbutyronitrile + NADPH + O2 <=> H2O + NADP + 2-hydroxy-2-methylbutyronitrile. RHEA:51948|MetaCyc:RXN-9642 go-plus.json http://purl.obolibrary.org/obo/GO_0102992 GO:0102995 biolink:MolecularActivity angelicin synthase activity Catalysis of the reaction: columbianetin + NADPH + O2 + H+ <=> angelicin + acetone + NADP + 2 H2O. RHEA:27481|EC:1.14.14.148|MetaCyc:RXN-9689 go-plus.json http://purl.obolibrary.org/obo/GO_0102995 GO:0102997 biolink:MolecularActivity progesterone 5beta- reductase activity Catalysis of the reaction: H+ + progesterone + NADPH <=> 5beta-pregnane-3,20-dione + NADP. MetaCyc:RXN-9726 go-plus.json http://purl.obolibrary.org/obo/GO_0102997 GO:0102996 biolink:MolecularActivity beta,beta digalactosyldiacylglycerol galactosyltransferase activity Catalysis of the reaction: a 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + a beta,beta digalactosyldiacylglycerol <=> a trigalactosyldiacylglycerol + a 1,2-diacyl-sn-glycerol. EC:2.4.1.184|MetaCyc:RXN-9721 go-plus.json http://purl.obolibrary.org/obo/GO_0102996 GO:0102999 biolink:MolecularActivity UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 2-hydroxylamino-4,6-dinitrotoluene <=> 2-hydroxylamino-4,6-dinitrotoluene-O-glucoside + UDP + H+. MetaCyc:RXN-9743 go-plus.json http://purl.obolibrary.org/obo/GO_0102999 GO:0102998 biolink:MolecularActivity 4-sulfomuconolactone hydrolase activity Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O <=> maleylacetate + sulfite + 2 H+. RHEA:33711|EC:3.1.1.92|MetaCyc:RXN-9733 go-plus.json http://purl.obolibrary.org/obo/GO_0102998 GO:0038096 biolink:BiologicalProcess Fc-gamma receptor signaling pathway involved in phagocytosis An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes. go-plus.json Fc gamma receptor-dependent phagocytosis|Fcgamma receptor-mediated phagocytosis|Fc-gamma receptor signalling pathway involved in phagocytosis|IgG-mediated phagocytosis http://purl.obolibrary.org/obo/GO_0038096 GO:0038095 biolink:BiologicalProcess Fc-epsilon receptor signaling pathway A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json Fc-epsilon receptor signalling pathway http://purl.obolibrary.org/obo/GO_0038095 GO:0038098 biolink:BiologicalProcess sequestering of BMP from receptor via BMP binding Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor. go-plus.json extracellular sequestering of BMP|extracellular sequestering of bone morphogenetic protein http://purl.obolibrary.org/obo/GO_0038098 GO:0038097 biolink:BiologicalProcess positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. go-plus.json positive regulation of mast cell activation by Fc-epsilon receptor signalling pathway|Fc epsilon RI-dependent mast cell activation|Fc epsilon RI-mediated mast cell activation http://purl.obolibrary.org/obo/GO_0038097 GO:0038099 biolink:BiologicalProcess nodal receptor complex assembly The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals). go-plus.json nodal receptor complex formation|ActRIIB.ALK4.EGF-CFC complex formation http://purl.obolibrary.org/obo/GO_0038099 CHEBI:7621 biolink:ChemicalSubstance norajmaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_7621 GO:0038090 biolink:BiologicalProcess positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another. go-plus.json positive regulation of cell migration by VEGF/PDGFR signaling pathway|VEGF/PDGFR-induced cell migration|positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signalling pathway http://purl.obolibrary.org/obo/GO_0038090 GO:0038092 biolink:BiologicalProcess nodal signaling pathway A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json nodal signalling pathway|nodal signaling http://purl.obolibrary.org/obo/GO_0038092 GO:0038091 biolink:BiologicalProcess positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation. go-plus.json VEGF-A-induced cell proliferation|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signalling pathway|positive regulation of cell proliferation by VEGF/PDGFR signaling pathway http://purl.obolibrary.org/obo/GO_0038091 GO:0038094 biolink:BiologicalProcess Fc-gamma receptor signaling pathway A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json Fc-gamma receptor signalling pathway http://purl.obolibrary.org/obo/GO_0038094 GO:0038093 biolink:BiologicalProcess Fc receptor signaling pathway A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. go-plus.json Fc receptor signalling pathway http://purl.obolibrary.org/obo/GO_0038093 CHEBI:147297 biolink:ChemicalSubstance omega-hydroxy-ultra-long-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_147297 GO:0038085 biolink:MolecularActivity vascular endothelial growth factor binding Binding to a vascular endothelial growth factor. go-plus.json VEGF binding http://purl.obolibrary.org/obo/GO_0038085 GO:0038084 biolink:BiologicalProcess vascular endothelial growth factor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json vascular endothelial growth factor signalling pathway|VEGF-activated signaling pathway|VEGF signaling http://purl.obolibrary.org/obo/GO_0038084 GO:0038087 biolink:BiologicalProcess VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json VEGF-A/PDGFRalpha signaling|VEGF-activated PDGFRalpha signalling pathway|VEGF/PDGFRalpha signaling pathway|vascular endothelial growth factor-activated platelet-derived growth factor receptor-alpha signaling pathway|VEGF-activated platelet-derived growth factor receptor-alpha signalling pathway http://purl.obolibrary.org/obo/GO_0038087 GO:0038086 biolink:BiologicalProcess VEGF-activated platelet-derived growth factor receptor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json vascular endothelial growth factor-activated platelet-derived growth factor receptor signaling pathway|VEGF-activated platelet-derived growth factor receptor signalling pathway|VEGF-activated PDGFR signalling pathway|VEGF/PDGFR signaling pathway|VEGF-A/PDGFR signaling http://purl.obolibrary.org/obo/GO_0038086 GO:0038089 biolink:BiologicalProcess positive regulation of cell migration by vascular endothelial growth factor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another. go-plus.json positive regulation of cell migration by vascular endothelial growth factor signalling pathway|VEGF-A-induced cell migration|positive regulation of cell migration by VEGF signaling pathway|VEGF-induced cell migration http://purl.obolibrary.org/obo/GO_0038089 GO:0038088 biolink:BiologicalProcess VEGF-activated platelet-derived growth factor receptor-beta signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json VEGF-activated platelet-derived growth factor receptor-beta signalling pathway|VEGF-A/PDGFRbeta signaling|vascular endothelial growth factor-activated platelet-derived growth factor receptor-beta signaling pathway|VEGF-activated PDGFRbeta signalling pathway|VEGF/PDGFRbeta signaling pathway http://purl.obolibrary.org/obo/GO_0038088 GO:0038081 biolink:MolecularActivity obsolete MAP kinase kinase kinase activity involved in osmosensory signaling pathway OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. go-plus.json MAP kinase kinase kinase activity involved in osmosensory signalling pathway|MAPKKK activity involved in osmosensory signaling pathway|MAP3K activity involved in osmosensory signaling pathway http://purl.obolibrary.org/obo/GO_0038081 GO:0038080 biolink:MolecularActivity obsolete MAP kinase kinase activity involved in osmosensory signaling pathway OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. go-plus.json MAP2K activity involved in osmosensory signaling pathway|MAPKK activity involved in osmosensory signaling pathway|MAP kinase kinase activity involved in osmosensory signalling pathway http://purl.obolibrary.org/obo/GO_0038080 GO:0038083 biolink:BiologicalProcess peptidyl-tyrosine autophosphorylation The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein. go-plus.json tyrosine autophosphorylation|receptor tyrosine kinase autophosphorylation|RTK autophosphorylation http://purl.obolibrary.org/obo/GO_0038083 GO:0038082 biolink:MolecularActivity obsolete MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. go-plus.json MAPK phosphatase activity involved in regulation of osmosensory signaling pathway|MAP kinase phosphatase activity involved in regulation of osmosensory signalling pathway|Hog1 phosphatase activity http://purl.obolibrary.org/obo/GO_0038082 CHEBI:147285 biolink:ChemicalSubstance EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_147285 CHEBI:147288 biolink:ChemicalSubstance omega-hydroxy-ultra-long-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_147288 chebi_ph7_3 GO:0038074 biolink:MolecularActivity obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion. go-plus.json MAPK phosphatase activity involved in regulation of conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0038074 GO:0038073 biolink:MolecularActivity obsolete MAP kinase kinase kinase activity involved in conjugation with cellular fusion OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis. go-plus.json MAPKKK activity involved in conjugation with cellular fusion|MAP3K activity involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0038073 GO:0038076 biolink:MolecularActivity obsolete MAP kinase kinase activity involved in innate immune response OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response. go-plus.json MAPKK activity involved in innate immune response|MAP2K activity involved in innate immune response http://purl.obolibrary.org/obo/GO_0038076 GO:0038075 biolink:MolecularActivity obsolete MAP kinase activity involved in innate immune response OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response. go-plus.json MAPK activity involved in innate immune response http://purl.obolibrary.org/obo/GO_0038075 GO:0038078 biolink:MolecularActivity obsolete MAP kinase phosphatase activity involved in regulation of innate immune response OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response. go-plus.json MAPK phosphatase activity involved in regulation of innate immune response http://purl.obolibrary.org/obo/GO_0038078 GO:0038077 biolink:MolecularActivity obsolete MAP kinase kinase kinase activity involved in innate immune response OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response. go-plus.json MAPKKK activity involved in innate immune response|MAP3K activity involved in innate immune response http://purl.obolibrary.org/obo/GO_0038077 GO:0038079 biolink:MolecularActivity obsolete MAP kinase activity involved in osmosensory signaling pathway OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. go-plus.json MAPK activity involved in osmosensory signaling pathway|MAP kinase activity involved in osmosensory signalling pathway http://purl.obolibrary.org/obo/GO_0038079 GO:0038070 biolink:MolecularActivity obsolete MAP kinase kinase kinase activity involved in cell wall organization or biogenesis OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis. go-plus.json MAP3K activity involved in cell wall integrity|MAP kinase kinase kinase activity involved in cell wall biogenesis|MAPKKK activity involved in cell wall integrity http://purl.obolibrary.org/obo/GO_0038070 GO:0038072 biolink:MolecularActivity obsolete MAP kinase kinase activity involved in conjugation with cellular fusion OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion. go-plus.json MAPKK activity involved in conjugation with cellular fusion|MAP2K activity involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0038072 GO:0038071 biolink:MolecularActivity obsolete MAP kinase activity involved in conjugation with cellular fusion OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion. go-plus.json MAPK activity involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0038071 UBERON:0006098 biolink:AnatomicalEntity basal nuclear complex The deep nuclei of telencephalic origin found in the basal region of the forebrain go-plus.json ganglia basales|corpus striatum (Savel'ev)|basal nuclei|basal ganglia (anatomic)|basal nuclei of the forebrain|basal ganglia http://purl.obolibrary.org/obo/UBERON_0006098 GO:0038063 biolink:BiologicalProcess collagen-activated tyrosine kinase receptor signaling pathway A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json DDR signaling pathway|discoidin domain receptor signaling pathway|collagen-activated RTK signaling pathway|collagen-activated tyrosine kinase receptor signalling pathway http://purl.obolibrary.org/obo/GO_0038063 GO:0038062 biolink:MolecularActivity protein tyrosine kinase collagen receptor activity Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. go-plus.json collagen RTK activity|discoidin domain receptor http://purl.obolibrary.org/obo/GO_0038062 GO:0038065 biolink:BiologicalProcess collagen-activated signaling pathway A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json collagen-activated signalling pathway http://purl.obolibrary.org/obo/GO_0038065 GO:0038064 biolink:MolecularActivity collagen receptor activity Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json transmembrane collagen receptor activity http://purl.obolibrary.org/obo/GO_0038064 GO:0038067 biolink:MolecularActivity obsolete MAP kinase activity involved in cell wall organization or biogenesis OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis. go-plus.json MAP kinase activity involved in cell wall integrity|MAP kinase activity involved in cell wall biogenesis|MAPK activity involved in cell wall biogenesis http://purl.obolibrary.org/obo/GO_0038067 GO:0038066 biolink:BiologicalProcess p38MAPK cascade An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. go-plus.json p38 MAPK cascade|p38 cascade http://purl.obolibrary.org/obo/GO_0038066 GO:0038069 biolink:MolecularActivity obsolete MAP kinase phosphatase activity involved in regulation of cell wall biogenesis OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis. go-plus.json Mpk1 phosphatase activity|Slt2 phosphatase activity http://purl.obolibrary.org/obo/GO_0038069 GO:0038068 biolink:MolecularActivity obsolete MAP kinase kinase activity involved in cell wall organization or biogenesis OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis. go-plus.json MAP kinase kinase activity involved in cell wall biogenesis|MAP2K activity involved in cell wall integrity|MAPKK activity involved in cell wall integrity http://purl.obolibrary.org/obo/GO_0038068 GO:0038061 biolink:BiologicalProcess NIK/NF-kappaB signaling The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52). go-plus.json noncanonical NF-kappaB signaling|p52-dependent NF-kappaB signaling|noncanonical nuclear factor kappaB (NF-kappaB) pathway|NIK/NF-kappaB signal transduction|non-canonical NF-KB signaling|NIK/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0038061 GO:0038060 biolink:BiologicalProcess nitric oxide-cGMP-mediated signaling pathway Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP. go-plus.json NO-cGMP signaling pathway|canonical nitric oxide signaling|nitric oxide-cGMP-mediated signalling pathway|classical nitric oxide signaling http://purl.obolibrary.org/obo/GO_0038060 GO:0102951 biolink:MolecularActivity indole-3-acetyl-phenylalanine synthetase activity Catalysis of the reaction: indole-3-acetate + L-phenylalanine + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid. MetaCyc:RXN-9084 go-plus.json http://purl.obolibrary.org/obo/GO_0102951 GO:0102950 biolink:MolecularActivity indole-3-acetyl-valine synthetase activity Catalysis of the reaction: indole-3-acetate + L-valine + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid. MetaCyc:RXN-9083 go-plus.json http://purl.obolibrary.org/obo/GO_0102950 GO:0102953 biolink:MolecularActivity hypoglycin A gamma-glutamyl transpeptidase activity Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B. MetaCyc:RXN-9157|EC:2.3.2.2 go-plus.json http://purl.obolibrary.org/obo/GO_0102953 GO:0102952 biolink:MolecularActivity UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP. RHEA:57708|MetaCyc:RXN-91 go-plus.json http://purl.obolibrary.org/obo/GO_0102952 GO:0102955 biolink:MolecularActivity S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+. RHEA:33255|MetaCyc:RXN-9191|EC:2.1.1.163 go-plus.json http://purl.obolibrary.org/obo/GO_0102955 GO:0102954 biolink:MolecularActivity dalcochinase activity Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose. MetaCyc:RXN-9162 go-plus.json http://purl.obolibrary.org/obo/GO_0102954 NCBITaxon:243277 biolink:OrganismalEntity Vibrio cholerae O1 biovar El Tor str. N16961 go-plus.json Vibrio cholerae serotype O1 biotype ElTor strain N16961|Vibrio cholerae O1 biovar eltor str. N16961|Vibrio cholerae El Tor N16961|Vibrio cholerae serotype O1 biotype El Tor strain N16961 http://purl.obolibrary.org/obo/NCBITaxon_243277 GO:0038059 biolink:CellularComponent IKKalpha-IKKalpha complex A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits. go-plus.json IkappaB kinase alpha homodimer|IKKalpha homodimeric complex|IKKalpha homodimer|IKKalpha-IKKalpha protein complex|IkappaB kinase-alpha homodimer http://purl.obolibrary.org/obo/GO_0038059 GO:0102956 biolink:MolecularActivity UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP. MetaCyc:RXN-92|RHEA:57712 go-plus.json http://purl.obolibrary.org/obo/GO_0102956 GO:0038052 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038052 GO:0038051 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038051 GO:0038054 biolink:MolecularActivity G protein-coupled estrogen receptor activity Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G-protein coupled estrogen receptor activity http://purl.obolibrary.org/obo/GO_0038054 GO:0038053 biolink:MolecularActivity obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements. go-plus.json estrogen-activated RNA polymerase II transcription factor binding transcription factor activity|estrogen nuclear receptor activity http://purl.obolibrary.org/obo/GO_0038053 GO:0038056 biolink:BiologicalProcess negative regulation of BMP signaling pathway by negative regulation of BMP secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell. go-plus.json negative regulation of BMP signalling pathway by negative regulation of BMP secretion|negative regulation of BMP signaling pathway by negative regulation of bone morphogenetic protein secretion http://purl.obolibrary.org/obo/GO_0038056 GO:0038055 biolink:BiologicalProcess BMP secretion The controlled release of a member of the BMP family of proteins from a cell. go-plus.json bone morphogenetic protein secretion|BMP protein secretion http://purl.obolibrary.org/obo/GO_0038055 GO:0038058 biolink:MolecularActivity TNFSF11 receptor activity Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function. go-plus.json tumor necrosis factor ligand superfamily member 11 receptor activity|RANKL receptor activity http://purl.obolibrary.org/obo/GO_0038058 GO:0038057 biolink:MolecularActivity TNFSF11 binding Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family. go-plus.json osteoclast differentiation factor binding|receptor activator of nuclear factor kappa-B ligand binding|tumor necrosis factor (ligand) superfamily member 11 binding|tumor necrosis factor superfamily member 11 binding|tumor necrosis factor ligand superfamily member 11 binding|OPGL binding|RANKL binding|TNF-related activation-induced cytokine binding|osteoprotegerin ligand binding|ODF binding|CD254 binding|TRANCE binding http://purl.obolibrary.org/obo/GO_0038057 GO:0038050 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038050 GO:0102960 biolink:MolecularActivity momilactone-A synthase activity Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H. EC:1.1.1.295|RHEA:25367|MetaCyc:RXN-9290 go-plus.json http://purl.obolibrary.org/obo/GO_0102960 GO:0102962 biolink:MolecularActivity 4,4'-diapo-zeta-carotene desaturase activity Catalysis of the reaction: all-trans-4,4'-diapo-zeta-carotene + FAD + H+ = 4,4'-diaponeurosporene + FADH2. MetaCyc:RXN-9305|RHEA:31403 go-plus.json http://purl.obolibrary.org/obo/GO_0102962 GO:0102961 biolink:MolecularActivity 4,4'-diapophytofluene desaturase activity Catalysis of the reaction: all-trans-4,4'-diapophytofluene + FAD + H+ = all-trans-4,4'-diapo-zeta-carotene + FADH2. MetaCyc:RXN-9304|RHEA:31399 go-plus.json http://purl.obolibrary.org/obo/GO_0102961 GO:0102964 biolink:MolecularActivity S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine <=> H+ + magnoflorine + S-adenosyl-L-homocysteine. MetaCyc:RXN-9315|RHEA:51524 go-plus.json http://purl.obolibrary.org/obo/GO_0102964 GO:0102963 biolink:MolecularActivity (S)-corytuberine synthase activity Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 <=> (S)-corytuberine + NADP + 2 H2O. MetaCyc:RXN-9314|EC:1.14.19.51|RHEA:51540 go-plus.json http://purl.obolibrary.org/obo/GO_0102963 GO:0102966 biolink:MolecularActivity arachidoyl-CoA:1-dodecanol O-acyltransferase activity Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A. MetaCyc:RXN-9356|EC:2.3.1.75 go-plus.json http://purl.obolibrary.org/obo/GO_0102966 GO:0102965 biolink:MolecularActivity alcohol-forming fatty acyl-CoA reductase activity Catalysis of the reaction: 2 NADPH + 2 H+ + a long-chain acyl-CoA = coenzyme A + 2 NADP + a long-chain alcohol. RHEA:52716|MetaCyc:RXN-9344|EC:1.2.1.84 go-plus.json http://purl.obolibrary.org/obo/GO_0102965 GO:0102968 biolink:MolecularActivity 10-hydroxygeranial oxidoreductase activity Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+. MetaCyc:RXN-9369|RHEA:32611 go-plus.json http://purl.obolibrary.org/obo/GO_0102968 GO:0038049 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038049 GO:0038048 biolink:MolecularActivity dynorphin receptor activity Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin. go-plus.json kappa-opioid receptor activity http://purl.obolibrary.org/obo/GO_0038048 GO:0102967 biolink:MolecularActivity 10-hydroxygeraniol oxidoreductase activity Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP <=> (6E)-8-hydroxygeranial + NADPH + H+. RHEA:32607|MetaCyc:RXN-9367 go-plus.json http://purl.obolibrary.org/obo/GO_0102967 NCBITaxon:243274 biolink:OrganismalEntity Thermotoga maritima MSB8 go-plus.json Thermotoga maritima strain MSB8|Thermotoga maritima str. MSB8|Thermotoga maritima DSM 3109 http://purl.obolibrary.org/obo/NCBITaxon_243274 NCBITaxon:243273 biolink:OrganismalEntity Mycoplasma genitalium G37 go-plus.json Mycoplasma genitalium ATCC 33530|Mycoplasma genitalium strain G37|Mycoplasma genitalium str. G37 http://purl.obolibrary.org/obo/NCBITaxon_243273 GO:0102969 biolink:MolecularActivity 10-oxogeraniol oxidoreductase activity Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+. RHEA:32615|MetaCyc:RXN-9370 go-plus.json http://purl.obolibrary.org/obo/GO_0102969 GO:0038041 biolink:BiologicalProcess cross-receptor inhibition within G protein-coupled receptor heterodimer Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit. go-plus.json cross-receptor inhibition within G-protein coupled receptor heterodimer http://purl.obolibrary.org/obo/GO_0038041 GO:0038040 biolink:BiologicalProcess obsolete cross-receptor activation within G-protein coupled receptor heterodimer OBSOLETE. Activation of one protomer of a consequence of a G protein-coupled (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0038040 GO:0038043 biolink:BiologicalProcess interleukin-5-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-5-mediated signaling pathway|interleukin-5-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0038043 CHEBI:7671 biolink:ChemicalSubstance O-acetylhomoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7671 GO:0038042 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038042 GO:0038045 biolink:CellularComponent large latent transforming growth factor-beta complex A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors. go-plus.json LLC|large latent complex http://purl.obolibrary.org/obo/GO_0038045 CHEBI:7676 biolink:ChemicalSubstance O-butanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7676 chebi_ph7_3 GO:0038044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038044 GO:0038047 biolink:MolecularActivity morphine receptor activity Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json mu-opioid receptor activity http://purl.obolibrary.org/obo/GO_0038047 GO:0038046 biolink:MolecularActivity G protein-coupled enkephalin receptor activity Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body. go-plus.json delta-opioid receptor activity|enkephalin receptor activity http://purl.obolibrary.org/obo/GO_0038046 GO:0014070 biolink:BiologicalProcess response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. go-plus.json response to organic cyclic substance http://purl.obolibrary.org/obo/GO_0014070 GO:0102971 biolink:MolecularActivity phosphinothricin N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + phosphinothricin <=> H+ + coenzyme A(4-) + N-acetylphosphinatothricinate. MetaCyc:RXN-9382|RHEA:12597|EC:2.3.1.183 go-plus.json http://purl.obolibrary.org/obo/GO_0102971 GO:0102970 biolink:MolecularActivity 7-deoxyloganetic acid glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate <=> H+ + 7-deoxyloganate + UDP. MetaCyc:RXN-9372|RHEA:39895|EC:2.4.1.323 go-plus.json http://purl.obolibrary.org/obo/GO_0102970 GO:0102973 biolink:MolecularActivity norsolorinate anthrone synthase activity Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein]. MetaCyc:RXN-9479|RHEA:35179|EC:2.3.1.221 go-plus.json norsolorinic acid synthase http://purl.obolibrary.org/obo/GO_0102973 GO:0102972 biolink:MolecularActivity gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming) Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide. MetaCyc:RXN-947 go-plus.json http://purl.obolibrary.org/obo/GO_0102972 GO:0102975 biolink:MolecularActivity versiconal hemiacetal acetate reductase activity Catalysis of the reaction: versiconol acetate + NADP <=> versiconal hemiacetal acetate + NADPH. MetaCyc:RXN-9490|RHEA:35695|EC:1.1.1.353 go-plus.json http://purl.obolibrary.org/obo/GO_0102975 GO:0102974 biolink:MolecularActivity hydroxyversicolorone reductase activity Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH. MetaCyc:RXN-9489|RHEA:35691|EC:1.1.1.353 go-plus.json http://purl.obolibrary.org/obo/GO_0102974 GO:0102977 biolink:MolecularActivity nitrilotriacetate monooxygenase activity (FMN-dependent) Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN. RHEA:31359|MetaCyc:RXN-9508|EC:1.14.14.10 go-plus.json http://purl.obolibrary.org/obo/GO_0102977 GO:0102976 biolink:MolecularActivity versiconal reductase activity Catalysis of the reaction: versiconol + NADP <=> versiconal hemiacetal + NADPH + H+. RHEA:35699|MetaCyc:RXN-9491|EC:1.1.1.353 go-plus.json http://purl.obolibrary.org/obo/GO_0102976 GO:0038038 biolink:CellularComponent G protein-coupled receptor homodimeric complex A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor. go-plus.json G-protein coupled receptor homodimer|GPCR homodimer|G-protein coupled receptor homodimeric complex http://purl.obolibrary.org/obo/GO_0038038 GO:0102979 biolink:MolecularActivity homofuraneol oxidoreductase activity Catalysis of the reaction: homofuraneol + NADP <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+. RHEA:53944|MetaCyc:RXN-9564 go-plus.json http://purl.obolibrary.org/obo/GO_0102979 GO:0038037 biolink:CellularComponent G protein-coupled receptor dimeric complex A protein complex that contains two G protein-coupled receptors. go-plus.json G-protein coupled receptor dimer|GPCR dimer|G-protein coupled receptor dimeric complex http://purl.obolibrary.org/obo/GO_0038037 GO:0102978 biolink:MolecularActivity furaneol oxidoreductase activity Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+. MetaCyc:RXN-9563|EC:1.3.1.105|RHEA:39111 go-plus.json http://purl.obolibrary.org/obo/GO_0102978 GO:0014069 biolink:CellularComponent postsynaptic density An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. Wikipedia:Postsynaptic_density|NIF_Subcellular:sao1196688972 go-plus.json neuronal postsynaptic density|post-synaptic density|postsynaptic density of dendrite|post synaptic density http://purl.obolibrary.org/obo/GO_0014069 goslim_synapse GO:0038039 biolink:CellularComponent G protein-coupled receptor heterodimeric complex A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR. go-plus.json GPCR heterodimer|G-protein coupled receptor heterodimer|G-protein coupled receptor heterodimeric complex http://purl.obolibrary.org/obo/GO_0038039 GO:0014068 biolink:BiologicalProcess positive regulation of phosphatidylinositol 3-kinase signaling Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. go-plus.json up regulation of phosphatidylinositol 3-kinase cascade|stimulation of phosphatidylinositol 3-kinase cascade|positive regulation of phosphatidylinositol 3-kinase cascade|up-regulation of phosphatidylinositol 3-kinase cascade|positive regulation of PI3K cascade|positive regulation of PI 3-kinase cascade|upregulation of phosphatidylinositol 3-kinase cascade|activation of phosphoinositide 3-kinase cascade|positive regulation of phosphoinositide 3-kinase cascade http://purl.obolibrary.org/obo/GO_0014068 GO:0014063 biolink:BiologicalProcess negative regulation of serotonin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. go-plus.json positive regulation of serotonin release|down regulation of serotonin secretion|downregulation of serotonin secretion|down-regulation of serotonin secretion|inhibition of serotonin secretion http://purl.obolibrary.org/obo/GO_0014063 GO:0038030 biolink:BiologicalProcess non-canonical Wnt signaling pathway via MAPK cascade The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the MAPKKK cascade. go-plus.json non-canonical Wnt receptor signaling pathway via MAPKKK cascade|non-canonical Wnt receptor signaling pathway via MAPK signaling|non-canonical Wnt-activated signaling pathway via MAPK cascade|non-canonical Wnt receptor signalling pathway via MAPKKK cascade|non-canonical Wnt receptor signaling pathway via MAPK cascade http://purl.obolibrary.org/obo/GO_0038030 GO:0014062 biolink:BiologicalProcess regulation of serotonin secretion Any process that modulates the frequency, rate or extent of the regulated release of serotonin. go-plus.json regulation of serotonin release http://purl.obolibrary.org/obo/GO_0014062 GO:0014061 biolink:BiologicalProcess regulation of norepinephrine secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. go-plus.json regulation of noradrenaline secretion http://purl.obolibrary.org/obo/GO_0014061 GO:0038032 biolink:BiologicalProcess termination of G protein-coupled receptor signaling pathway The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal. go-plus.json termination of G-protein coupled receptor signalling pathway|termination of GPCR signaling pathway|termination of G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038032 GO:0014060 biolink:BiologicalProcess regulation of epinephrine secretion Any process that modulates the frequency, rate or extent of the regulated release of epinephrine. go-plus.json regulation of adrenaline secretion http://purl.obolibrary.org/obo/GO_0014060 GO:0038031 biolink:BiologicalProcess non-canonical Wnt signaling pathway via JNK cascade The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade. go-plus.json non-canonical Wnt-activated signaling pathway via JNK cascade|non-canonical Wnt receptor signaling pathway via JNK cascade|non-canonical Wnt receptor signalling pathway via JNK cascade http://purl.obolibrary.org/obo/GO_0038031 GO:0014067 biolink:BiologicalProcess negative regulation of phosphatidylinositol 3-kinase signaling Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. go-plus.json negative regulation of phosphoinositide 3-kinase cascade|downregulation of phosphatidylinositol 3-kinase cascade|down-regulation of phosphatidylinositol 3-kinase cascade|negative regulation of phosphatidylinositol 3-kinase cascade|inhibition of phosphatidylinositol 3-kinase cascade|negative regulation of PI3K cascade|negative regulation of PI 3-kinase cascade|down regulation of phosphatidylinositol 3-kinase cascade http://purl.obolibrary.org/obo/GO_0014067 GO:0038034 biolink:BiologicalProcess signal transduction in absence of ligand A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor. go-plus.json basal signaling|dependence receptor signaling pathway|signal transduction in absence of agonist|non-classical signal transduction|addiction receptor signaling pathway|negative signal transduction http://purl.obolibrary.org/obo/GO_0038034 GO:0038033 biolink:BiologicalProcess positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis. go-plus.json positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signalling pathway|VEGF-mediated chemotactic endothelial cell migration|positive regulation of endothelial cell chemotaxis by VEGF/VEGFR signaling pathway|vascular endothelial growth factor receptor signaling pathway involved in endothelial cell chemotaxis|VEGF-VEGFR-induced endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0038033 GO:0014066 biolink:BiologicalProcess regulation of phosphatidylinositol 3-kinase signaling Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. go-plus.json regulation of phosphatidylinositol 3-kinase cascade|regulation of phosphoinositide 3-kinase cascade|regulation of PI 3-kinase cascade|regulation of PI3K cascade http://purl.obolibrary.org/obo/GO_0014066 GO:0014065 biolink:BiologicalProcess phosphatidylinositol 3-kinase signaling A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions. go-plus.json phosphoinositide 3-kinase cascade|PI3K cascade|phosphatidylinositol 3-kinase signal transduction|PI3K signaling|PI3K signal transduction|phosphatidylinositol 3-kinase cascade|PI 3-kinase cascade http://purl.obolibrary.org/obo/GO_0014065 GO:0038036 biolink:MolecularActivity sphingosine-1-phosphate receptor activity Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json S1P receptor activity http://purl.obolibrary.org/obo/GO_0038036 GO:0014064 biolink:BiologicalProcess positive regulation of serotonin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. go-plus.json positive regulation of serotonin release|upregulation of serotonin secretion|up regulation of serotonin secretion|activation of serotonin secretion|stimulation of serotonin secretion|up-regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0014064 GO:0038035 biolink:BiologicalProcess G protein-coupled receptor signaling in absence of ligand A series of molecular signals beginning with a consequence of a G protein-coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G protein-coupled receptor is not bound to an agonist. go-plus.json basal G-protein coupled receptor signaling|G-protein coupled receptor signaling in absence of ligand|G-protein coupled receptor signaling in absence of agonist|G-protein coupled receptor signalling in absence of ligand http://purl.obolibrary.org/obo/GO_0038035 GO:0102980 biolink:MolecularActivity 2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+. MetaCyc:RXN-9565 go-plus.json http://purl.obolibrary.org/obo/GO_0102980 GO:0102982 biolink:MolecularActivity UDP-3-dehydro-alpha-D-glucose dehydrogenase activity Catalysis of the reaction: UDP-alpha-D-glucose + NAD <=> H+ + UDP-3-keto-alpha-D-glucose + NADH. MetaCyc:RXN-9578|RHEA:35755 go-plus.json http://purl.obolibrary.org/obo/GO_0102982 GO:0102981 biolink:MolecularActivity 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity Catalysis of the reaction: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+. MetaCyc:RXN-9567 go-plus.json http://purl.obolibrary.org/obo/GO_0102981 GO:0102984 biolink:MolecularActivity sulfoacetaldehyde dehydrogenase activity Catalysis of the reaction: sulfonatoacetaldehyde + H2O + NAD <=> sulfonatoacetate + NADH + 2 H+. RHEA:25637|EC:1.2.1.73|MetaCyc:RXN-9592 go-plus.json http://purl.obolibrary.org/obo/GO_0102984 GO:0102983 biolink:MolecularActivity xylogalacturonan beta-1,3-xylosyltransferase activity Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan. MetaCyc:RXN-9589|EC:2.4.2.41 go-plus.json http://purl.obolibrary.org/obo/GO_0102983 GO:0102986 biolink:MolecularActivity trehalose synthase activity Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate. EC:2.4.1.245|MetaCyc:RXN-9603|RHEA:47416 go-plus.json http://purl.obolibrary.org/obo/GO_0102986 GO:0102985 biolink:MolecularActivity delta12-fatty-acid desaturase activity Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9. EC:1.14.19.6|MetaCyc:RXN-9601|RHEA:25856 go-plus.json http://purl.obolibrary.org/obo/GO_0102985 GO:0102988 biolink:MolecularActivity 9,12-cis-hexadecadienoic acid delta 15 desaturase activity Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-9617|RHEA:46232 go-plus.json http://purl.obolibrary.org/obo/GO_0102988 GO:0102987 biolink:MolecularActivity palmitoleic acid delta 12 desaturase activity Catalysis of the reaction: palmitoleoyl-CoA + O2 + a reduced electron acceptor <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 H2O + an oxidized electron acceptor. RHEA:45096|MetaCyc:RXN-9616 go-plus.json http://purl.obolibrary.org/obo/GO_0102987 GO:0038027 biolink:BiologicalProcess apolipoprotein A-I-mediated signaling pathway A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json apolipoprotein A-I-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0038027 GO:0038026 biolink:BiologicalProcess reelin-mediated signaling pathway A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json reelin-mediated signalling pathway|reeler-mediated signaling pathway|reelin-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0038026 GO:0102989 biolink:MolecularActivity 5-pentadecatrienylresorcinol synthase activity Catalysis of the reaction: 3 H+ + 9,12,15-cis-hexadecatrienoyl-CoA + 3 malonyl-CoA(5-) <=> 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + 4 coenzyme A + 4 carbon dioxide. MetaCyc:RXN-9618 go-plus.json http://purl.obolibrary.org/obo/GO_0102989 GO:0038029 biolink:BiologicalProcess epidermal growth factor receptor signaling pathway via MAPK cascade The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade. go-plus.json EGFR signaling via MAPKKK cascade|epidermal growth factor receptor signaling pathway via MAPKKK cascade|EGFR/MAPK signaling|EGFR signaling pathway via MAPKKK cascade|epidermal growth factor receptor signalling pathway via MAPKKK cascade http://purl.obolibrary.org/obo/GO_0038029 GO:0038028 biolink:BiologicalProcess insulin receptor signaling pathway via phosphatidylinositol 3-kinase The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade. go-plus.json insulin receptor signaling pathway via PI3K cascade|insulin receptor signalling pathway via phosphatidylinositol 3-kinase cascade|insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade|insulin receptor signaling via PI3K http://purl.obolibrary.org/obo/GO_0038028 GO:0014074 biolink:BiologicalProcess response to purine-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. go-plus.json response to purine http://purl.obolibrary.org/obo/GO_0014074 GO:0014073 biolink:BiologicalProcess response to tropane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine. go-plus.json http://purl.obolibrary.org/obo/GO_0014073 GO:0014072 biolink:BiologicalProcess response to isoquinoline alkaloid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids. go-plus.json http://purl.obolibrary.org/obo/GO_0014072 GO:0038021 biolink:MolecularActivity leptin receptor activity Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0038021 GO:0038020 biolink:BiologicalProcess insulin receptor recycling The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. go-plus.json http://purl.obolibrary.org/obo/GO_0038020 GO:0014071 biolink:BiologicalProcess response to cycloalkane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n. go-plus.json http://purl.obolibrary.org/obo/GO_0014071 GO:0038023 biolink:MolecularActivity signaling receptor activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. go-plus.json receptor activity involved in signal transduction|signalling receptor activity|receptor activity http://purl.obolibrary.org/obo/GO_0038023 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_metagenomics GO:0038022 biolink:MolecularActivity G protein-coupled olfactory receptor activity Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json odorant receptor activity, G-protein coupled|G-protein coupled olfactory receptor activity|G-protein coupled odorant receptor activity|olfactory receptor activity, G-protein coupled http://purl.obolibrary.org/obo/GO_0038022 GO:0038025 biolink:MolecularActivity reelin receptor activity Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json reeler receptor activity http://purl.obolibrary.org/obo/GO_0038025 GO:0014076 biolink:BiologicalProcess response to fluoxetine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. go-plus.json response to selective serotonin reuptake inhibitor|response to SSRI http://purl.obolibrary.org/obo/GO_0014076 gocheck_do_not_manually_annotate GO:0038024 biolink:MolecularActivity cargo receptor activity Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. Reactome:R-HSA-3000122|Reactome:R-HSA-350168 go-plus.json receptor activity|transport receptor activity|endocytic receptor activity|receptor activity involved in receptor-mediated endocytosis http://purl.obolibrary.org/obo/GO_0038024 GO:0014075 biolink:BiologicalProcess response to amine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. go-plus.json response to amine stimulus http://purl.obolibrary.org/obo/GO_0014075 NCBITaxon:243232 biolink:OrganismalEntity Methanocaldococcus jannaschii DSM 2661 go-plus.json Methanocaldococcus jannaschii str. DSM 2661|Methanococcus jannaschii DSM 2661 http://purl.obolibrary.org/obo/NCBITaxon_243232 NCBITaxon:243231 biolink:OrganismalEntity Geobacter sulfurreducens PCA go-plus.json Geobacter sulfurreducens str. PCA|Geobacter sulfurreducens strain PCA http://purl.obolibrary.org/obo/NCBITaxon_243231 CHEBI:18634 biolink:ChemicalSubstance (L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_18634 PO:0025099 biolink:OntologyClass embryo plant structure A plant structure (PO:0009011) that is part of an plant embryo (PO:0009009). go-plus.json 胚性植物構造 (Japanese, exact)|embryonic plant structure (exact)|estructura vegetal embriónica (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025099 NCBITaxon:41666 biolink:OrganismalEntity Batrachia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_41666 PO:0025097 biolink:OntologyClass stamen epidermis A portion of phyllome epidermis (PO:0025157) that is part of a stamen (PO:0009029). go-plus.json 雄蕊表皮 (Japanese, exact)|epidermis del estambre (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025097 PO:0025096 biolink:OntologyClass carpel epidermis A portion of phyllome epidermis (PO:0025157) that is part of a carpel (PO:0009030). go-plus.json 心皮 表皮 (Japanese, exact)|A portion of carpel epidermis (PO:0025096) that covers the abaxial surface of a carpel (PO:0009030). " (broad)|epidermis del carpelo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025096 PO:0025095 biolink:OntologyClass root parenchyma A portion of parenchyma tissue (PO:0005421) that is part of a root (PO:0009005). go-plus.json 根柔組織 (Japanese, exact)|parénquima de la raíz (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025095 PO:0025094 biolink:OntologyClass sporangium A plant organ (PO:0009008) in which plant spores (PO:0025017) are produced. go-plus.json moss capsule (exact)|spore case (exact)|esporangio (Spanish, exact)|sporangia (exact, plural)|胞子嚢 (Japanese, exact)|spore capsule (exact) http://purl.obolibrary.org/obo/PO_0025094 PO:0025092 biolink:OntologyClass dehiscence zone A portion of plant tissue (PO:0009007) that is part of a plant structure and consists of a narrow band of cells that undergoes dehiscence upon maturation of the structure. go-plus.json 裂開帯 (Japanese, exact)|zona de dehiscencia (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025092 NCBITaxon:41665 biolink:OrganismalEntity Neopterygii go-plus.json Neopterygi http://purl.obolibrary.org/obo/NCBITaxon_41665 NCBITaxon:243230 biolink:OrganismalEntity Deinococcus radiodurans R1 go-plus.json Deinococcus radiodurans str. R1 http://purl.obolibrary.org/obo/NCBITaxon_243230 PO:0025082 biolink:OntologyClass reproductive shoot system A shoot system (PO:0009006) in the sporophytic phase that has as part at least one sporangium (PO:0025094). go-plus.json 生殖シュート 系、苗条系 (Japanese, exact)|sistema de brote reproductivo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025082 CHEBI:18657 biolink:ChemicalSubstance (R)-2-trans-abscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_18657 PO:0025078 biolink:OntologyClass placenta A portion of plant tissue (PO:0009007) at the interface between two plant structures, one of which is in a gametophyte development stage (PO:0028003) and one of which is in a sporophyte development stage (PO:0028002), and that has as parts transfer cells (PO:0000078). go-plus.json placentas (exact, plural)|placenta (Spanish, exact)|portion of placenta tissue (exact)|胎座 (Japanese, exact)|placentae (exact, plural) http://purl.obolibrary.org/obo/PO_0025078 PO:0025074 biolink:OntologyClass embryo sac A megagametophyte (PO:0025279) that is located in a plant ovary ovule (PO:0025490). go-plus.json 胚嚢 (Japanese, exact)|saco embrionario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025074 CHEBI:371 biolink:ChemicalSubstance (S)-1-pyrroline-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_371 UBERON:0006072 biolink:AnatomicalEntity cervical region of vertebral column That portion of the spine comprising the cervical vertebrae. The neck area of the spine. go-plus.json cervical vertebrae series|cervical skeleton|cervical vertebral column|axial skeleton cervical region|skeletal system of neck|cervical spinal column|cervical spine http://purl.obolibrary.org/obo/UBERON_0006072 UBERON:0006071 biolink:AnatomicalEntity caudal region Subdivision of an organism along anterior-posterior axis that is the posteriormost region, extending past the anus (or cloaca, if present), consisting of a tail in some fully formed chordates (or a tail bud in embryos). In animals that have a sacral region, this is the region immediately posterior to this. go-plus.json post-anal tail region|tail region|post-anal caudal region|postsacral region http://purl.obolibrary.org/obo/UBERON_0006071 UBERON:0006077 biolink:AnatomicalEntity subdivision of vertebral column A collection of all skeletal elements in some subdivision of the vertebral column. go-plus.json vertebral series|vertebral region|vertebral subdivision|subdivision of vertebral skeleton|vertebral column subdivision|vertebrae series http://purl.obolibrary.org/obo/UBERON_0006077 UBERON:0006076 biolink:AnatomicalEntity caudal region of vertebral column Subdivision of vertebral column that corresponds to the caudal subdivision of the body, containing the caudal vertebrae. go-plus.json postsacral region|tail region|caudal vertebrae series|caudal region|caudal skeleton|axial skeleton tail region http://purl.obolibrary.org/obo/UBERON_0006076 UBERON:0006073 biolink:AnatomicalEntity thoracic region of vertebral column That part of the spine comprising the thoracic vertebrae. go-plus.json thoracic vertebrae series|thoracic spine|thoracic vertebral column|axial skeleton thoracic region|columna vertebralis thoracicus http://purl.obolibrary.org/obo/UBERON_0006073 UBERON:0006061 biolink:AnatomicalEntity process of vertebra A process projection from a part of the vertebra such as centrum or arches. Examples: transverse process, diapophyses, parapophyses, and zygapophyses (both the cranial zygapophyses and the caudal zygapophyses). go-plus.json vertebra process|spinous process|vertebral process http://purl.obolibrary.org/obo/UBERON_0006061 UBERON:0006068 biolink:AnatomicalEntity bone of tail A bone that is part of a post-anal tail. go-plus.json tail bone|tail vertebra http://purl.obolibrary.org/obo/UBERON_0006068 UBERON:0006067 biolink:AnatomicalEntity musculature of hindlimb zeugopod Any collection of muscles that is part of a hindlimb zeugopod. go-plus.json muscle group of leg|leg musculature|set of muscles of leg http://purl.obolibrary.org/obo/UBERON_0006067 UBERON:0006063 biolink:AnatomicalEntity cartilaginous neural arch One of the cartilaginous structures surrounding the embryonic spinal cord, formed by the dorsal growth of the dorsolateral arcualia; it is the primordium of the vertebral arch. go-plus.json neural arch primordium http://purl.obolibrary.org/obo/UBERON_0006063 CHEBI:18608 biolink:ChemicalSubstance 5-methyltetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_18608 chebi_ph7_3 UBERON:0006058 biolink:AnatomicalEntity multi-limb segment region A collection of two or more connected limb segments. Examples: arm (comprising stylopod and zeugopod regions). go-plus.json http://purl.obolibrary.org/obo/UBERON_0006058 UBERON:0006056 biolink:AnatomicalEntity posterior surface of head go-plus.json http://purl.obolibrary.org/obo/UBERON_0006056 GO:0004646 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004646 GO:0004645 biolink:MolecularActivity 1,4-alpha-oligoglucan phosphorylase activity Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase. EC:2.4.1.1|MetaCyc:RXN-1826 go-plus.json starch phosphorylase|granulose phosphorylase|muscle phosphorylase a and b activity|muscle phosphorylase|1,4-alpha-glucan phosphorylase activity|amylophosphorylase activity|potato phosphorylase|1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity|glucosan phosphorylase|glucan phosphorylase|polyphosphorylase activity|alpha-glucan phosphorylase|myophosphorylase|amylopectin phosphorylase http://purl.obolibrary.org/obo/GO_0004645 GO:0004648 biolink:MolecularActivity O-phospho-L-serine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate. Reactome:R-HSA-977333|RHEA:14329|MetaCyc:PSERTRANSAM-RXN|EC:2.6.1.52 go-plus.json phosphohydroxypyruvate transaminase activity|phosphoserine aminotransferase activity|hydroxypyruvic phosphate--glutamic transaminase activity|phosphohydroxypyruvic--glutamic transaminase activity|phosphoserine transaminase activity|3-phosphoserine aminotransferase activity|3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity|SerC|L-phosphoserine aminotransferase activity|PdxC|3PHP transaminase activity|PSAT activity http://purl.obolibrary.org/obo/GO_0004648 GO:0004647 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004647 GO:0004642 biolink:MolecularActivity phosphoribosylformylglycinamidine synthase activity Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate. Reactome:R-HSA-73812|EC:6.3.5.3|RHEA:17129|KEGG_REACTION:R04463|MetaCyc:FGAMSYN-RXN go-plus.json phosphoribosylformylglycinamidine synthetase activity|2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|phosphoribosylformylglycineamidine synthetase activity|FGARAT activity|N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|FGAM synthase activity|FGAR amidotransferase activity|formylglycinamide ribonucloetide amidotransferase activity|5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)|formylglycinamide ribotide amidotransferase activity|FGAM synthetase activity http://purl.obolibrary.org/obo/GO_0004642 GO:0004641 biolink:MolecularActivity phosphoribosylformylglycinamidine cyclo-ligase activity Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate. KEGG_REACTION:R04208|EC:6.3.3.1|RHEA:23032|Reactome:R-HSA-73810|MetaCyc:AIRS-RXN go-plus.json 5'-aminoimidazole ribonucleotide synthetase activity|2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|AIRS activity|2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|AIR synthase activity|phosphoribosylaminoimidazole synthetase activity|phosphoribosyl-aminoimidazole synthetase activity|AIR synthetase activity http://purl.obolibrary.org/obo/GO_0004641 GO:0004644 biolink:MolecularActivity phosphoribosylglycinamide formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide. Reactome:R-HSA-73813|MetaCyc:GART-RXN|RHEA:15053|EC:2.1.2.2 go-plus.json 2-amino-N-ribosylacetamide 5'-phosphate transformylase activity|GAR formyltransferase activity|glycinamide ribonucleotide transformylase activity|5'-phosphoribosylglycinamide transformylase activity|GAR TFase activity|GART activity|GAR transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity|5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity http://purl.obolibrary.org/obo/GO_0004644 GO:0004643 biolink:MolecularActivity phosphoribosylaminoimidazolecarboxamide formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide. MetaCyc:AICARTRANSFORM-RXN|RHEA:22192|EC:2.1.2.3|Reactome:R-HSA-73798 go-plus.json AICAR transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity|5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity|5-amino-4-imidazolecarboxamide ribotide transformylase activity|5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|aminoimidazolecarboxamide ribonucleotide transformylase activity|5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|AICAR formyltransferase activity http://purl.obolibrary.org/obo/GO_0004643 GO:0004640 biolink:MolecularActivity phosphoribosylanthranilate isomerase activity Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. MetaCyc:PRAISOM-RXN|EC:5.3.1.24|RHEA:21540|KEGG_REACTION:R03509 go-plus.json PRA isomerase activity|N-(5'-phosphoribosyl)anthranilate isomerase activity|IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)|N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity|PRAI activity|N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0004640 CHEBI:137932 biolink:ChemicalSubstance 5-dehydro-L-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137932 CHEBI:137931 biolink:ChemicalSubstance TDP-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137931 chebi_ph7_3 CHEBI:137935 biolink:ChemicalSubstance S-polyprenyl-L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137935 chebi_ph7_3 CHEBI:137934 biolink:ChemicalSubstance polyprenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_137934 chebi_ph7_3 CHEBI:137933 biolink:ChemicalSubstance N(4)-methyl-dCMP(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137933 chebi_ph7_3 GO:0004649 biolink:MolecularActivity poly(ADP-ribose) glycohydrolase activity Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose. Reactome:R-HSA-5651828|RHEA:52216|Reactome:R-HSA-8952903|MetaCyc:3.2.1.143-RXN|EC:3.2.1.143 go-plus.json http://purl.obolibrary.org/obo/GO_0004649 GO:0004657 biolink:MolecularActivity proline dehydrogenase activity Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor. Reactome:R-HSA-6784224|Reactome:R-HSA-70670|EC:1.5.99.8|Reactome:R-HSA-8955817|MetaCyc:RXN-7181|RHEA:23784 go-plus.json L-proline:(acceptor) oxidoreductase activity|L-proline:acceptor oxidoreductase activity|L-proline dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004657 GO:0004656 biolink:MolecularActivity procollagen-proline 4-dioxygenase activity Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. MetaCyc:1.14.11.2-RXN|EC:1.14.11.2|KEGG_REACTION:R03219|RHEA:18945|Reactome:R-HSA-1650808 go-plus.json procollagen-proline,2-oxoglutarate-4-dioxygenase activity|protocollagen hydroxylase activity|protocollagen proline 4-hydroxylase activity|peptidyl proline hydroxylase activity|protocollagen prolyl hydroxylase activity|hydroxylase, collagen proline activity|prolylprotocollagen hydroxylase activity|prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity|prolyl hydroxylase activity|protocollagen proline dioxygenase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity|collagen proline hydroxylase activity|prolyl 4-hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity|proline, 2-oxoglutarate dioxygenase activity|protocollagen proline hydroxylase activity|proline protocollagen hydroxylase activity|prolylprotocollagen dioxygenase activity|proline hydroxylase activity http://purl.obolibrary.org/obo/GO_0004656 GO:0004659 biolink:MolecularActivity prenyltransferase activity Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). Reactome:R-HSA-6806674|MetaCyc:GPPSYN-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0004659 GO:0004658 biolink:MolecularActivity propionyl-CoA carboxylase activity Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA. MetaCyc:PROPIONYL-COA-CARBOXY-RXN|Reactome:R-HSA-71031|RHEA:23720|EC:6.4.1.3 go-plus.json propanoyl-CoA:carbon-dioxide ligase (ADP-forming)|propionyl coenzyme A carboxylase activity|PCCase activity http://purl.obolibrary.org/obo/GO_0004658 PO:0025131 biolink:OntologyClass plant anatomical entity An anatomical entity that is or was part of a plant. go-plus.json entidad anatómica vegetal (Spanish, exact)|植物 解剖学（形態）的実体 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025131 GO:0004653 biolink:MolecularActivity polypeptide N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis. MetaCyc:2.4.1.41-RXN|Reactome:R-HSA-9683760|Reactome:R-HSA-913675|Reactome:R-HSA-5096532|EC:2.4.1.41|Reactome:R-HSA-5096537|Reactome:R-HSA-8851619|Reactome:R-HSA-9694438 go-plus.json UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|polypeptide-N-acetylgalactosamine transferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity|protein-UDP acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity|glycoprotein acetylgalactosaminyltransferase activity|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity|UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0004653 GO:0004652 biolink:MolecularActivity polynucleotide adenylyltransferase activity Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group. Reactome:R-HSA-72185|MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.19|RHEA:11332 go-plus.json ATP:polynucleotidylexotransferase activity|RNA adenylating enzyme activity|AMP polynucleotidylexotransferase activity|polyadenylic acid polymerase activity|ATP:polynucleotide adenylyltransferase activity|terminal riboadenylate transferase activity|polyadenylate nucleotidyltransferase activity|poly(A) hydrolase activity|NTP polymerase activity|polyadenylate polymerase activity|adenosine triphosphate:ribonucleic acid adenylyltransferase activity|polyadenylic polymerase activity|poly(A) polymerase activity|polyadenylate synthetase activity|ATP-polynucleotide adenylyltransferase activity|RNA formation factors, PF1|poly(A) synthetase activity|poly-A polymerase activity http://purl.obolibrary.org/obo/GO_0004652 GO:0004655 biolink:MolecularActivity porphobilinogen synthase activity Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen. EC:4.2.1.24|KEGG_REACTION:R00036|MetaCyc:PORPHOBILSYNTH-RXN|Reactome:R-HSA-189439|RHEA:24064 go-plus.json delta-aminolevulinic dehydratase activity|delta-aminolevulinic acid dehydratase activity|aminolevulinate dehydratase activity|aminolevulinic dehydratase activity|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)|5-levulinic acid dehydratase activity|delta-aminolevulinate dehydratase activity|delta-aminolevulinic acid dehydrase activity http://purl.obolibrary.org/obo/GO_0004655 GO:0004654 biolink:MolecularActivity polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. MetaCyc:2.7.7.8-RXN|EC:2.7.7.8|RHEA:22096 go-plus.json polyribonucleotide phosphorylase activity|nucleoside diphosphate:polynucleotidyl transferase activity|polyribonucleotide:phosphate nucleotidyltransferase activity|polynucleotide phosphorylase activity http://purl.obolibrary.org/obo/GO_0004654 GO:0004651 biolink:MolecularActivity polynucleotide 5'-phosphatase activity Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate. MetaCyc:POLYNUCLEOTIDE-5-PHOSPHATASE-RXN|RHEA:11008|EC:3.1.3.33|Reactome:R-HSA-77078 go-plus.json polynucleotide 5'-phosphohydrolase activity|polynucleotide 5'-triphosphatase activity|5'-polynucleotidase activity http://purl.obolibrary.org/obo/GO_0004651 CHEBI:137949 biolink:ChemicalSubstance O(3)-(beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137949 chebi_ph7_3 GO:0004650 biolink:MolecularActivity polygalacturonase activity Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans. MetaCyc:RXN-2103|EC:3.2.1.15 go-plus.json endo-polygalacturonase activity|endo-D-galacturonase activity|endopolygalacturonase activity|pectolase activity|pectin depolymerase activity|poly-alpha-1,4-galacturonide glycanohydrolase activity|pectin polygalacturonase activity|poly(1,4-alpha-D-galacturonide) glycanohydrolase activity|endogalacturonase activity|pectinase activity|pectin hydrolase activity http://purl.obolibrary.org/obo/GO_0004650 CHEBI:137948 biolink:ChemicalSubstance N-carbamoyl-D-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137948 CHEBI:137942 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137942 chebi_ph7_3 CHEBI:137941 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_137941 chebi_ph7_3 CHEBI:137945 biolink:ChemicalSubstance N-carbamoyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137945 PO:0025128 biolink:OntologyClass phyllome primordium A primordium (PO:0025127) that develops from a phyllome anlagen (PO:0025430) and is part of a shoot apex (PO:0000037) and is committed to the development of a phyllome (PO:0006001). go-plus.json phyllome primordia (exact, plural)|portion of phyllome primordium tissue (exact)|フィロム原基（可視的） (Japanese, exact)|primordio del filoma (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025128 PO:0025127 biolink:OntologyClass primordium A portion of meristem tissue (PO:0009013) that has as parts protoderm (PO:0006210) and sub-epidermal meristematic tissue and is committed to the development of a particular plant structure (PO:0009011). go-plus.json portion of primordial tissue (exact)|primordia (exact, plural)|primordio (Spanish, exact)|portion of primordium tissue (exact)|原基（可視的） (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025127 CHEBI:18584 biolink:ChemicalSubstance (5-L-glutamyl)-L-amino acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_18584 PO:0025123 biolink:OntologyClass embryo sac egg cell A plant egg cell (PO:0020094) that is part of an egg apparatus (PO:0020096). go-plus.json 胚嚢卵細胞 (Japanese, exact)|oocélula del saco embrionario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025123 GO:0004624 biolink:MolecularActivity obsolete secreted phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. go-plus.json secreted phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0004624 GO:0004623 biolink:MolecularActivity phospholipase A2 activity Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides. Reactome:R-HSA-1482759|Reactome:R-HSA-1482816|Reactome:R-HSA-1482900|Reactome:R-HSA-1482778|MetaCyc:RXN-15067|Reactome:R-HSA-1482679|Reactome:R-HSA-1482887|Reactome:R-HSA-1482856|Reactome:R-HSA-1482897|MetaCyc:PHOSPHOLIPASE-A2-RXN|EC:3.1.1.4|Reactome:R-HSA-1602417|Reactome:R-HSA-1482884|Reactome:R-HSA-1482771|Reactome:R-HSA-1602446|Reactome:R-HSA-1482907|RHEA:15801|Reactome:R-HSA-1482825|Reactome:R-HSA-1482868|Reactome:R-HSA-1602399|Reactome:R-HSA-1602374|Reactome:R-HSA-1482745|Reactome:R-HSA-1602398|Reactome:R-HSA-1602368|Reactome:R-HSA-1482656|Reactome:R-HSA-1482604|Reactome:R-HSA-8848484|Reactome:R-HSA-1482776|Reactome:R-HSA-1602377|MetaCyc:RXN-15065 go-plus.json cytosolic phospholipase A2 activity|secreted phospholipase A2 activity|phosphatidolipase activity|phosphatidylcholine 2-acylhydrolase activity|phosphatidase activity|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)|lecithinase A activity http://purl.obolibrary.org/obo/GO_0004623 goslim_chembl GO:0004626 biolink:MolecularActivity obsolete cytosolic phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. go-plus.json cytosolic phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0004626 PO:0025121 biolink:OntologyClass pollen sperm cell A plant sperm cell (PO:0000084) that is part of the pollen (PO:0025281). go-plus.json 花粉精子細胞 (Japanese, exact)|célula espermática polínica (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025121 GO:0004625 biolink:MolecularActivity obsolete calcium-dependent secreted phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. go-plus.json calcium-dependent secreted phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0004625 GO:0004620 biolink:MolecularActivity phospholipase activity Catalysis of the hydrolysis of a glycerophospholipid. Reactome:R-HSA-6786650|Reactome:R-HSA-6792445|EC:3.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0004620 goslim_chembl GO:0004622 biolink:MolecularActivity lysophospholipase activity Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate. Reactome:R-HSA-1482612|Reactome:R-HSA-6814766|Reactome:R-HSA-6814778|Reactome:R-HSA-1482685|Reactome:R-HSA-8847912|RHEA:15177|EC:3.1.1.5|Reactome:R-HSA-1482629|Reactome:R-HSA-1482545|Reactome:R-HSA-6814254|MetaCyc:LYSOPHOSPHOLIPASE-RXN|Reactome:R-HSA-1482571|Reactome:R-HSA-1482696 go-plus.json 2-lysophosphatidylcholine acylhydrolase activity|lysophosphatidase activity|lysophospholipase A1|lysolecithinase activity|lysophopholipase L2|lysophosphatidylcholine hydrolase activity|lecitholipase activity|phosphatidase B|lecithinase B activity|phospholipase B activity http://purl.obolibrary.org/obo/GO_0004622 goslim_chembl GO:0004621 biolink:MolecularActivity glycosylphosphatidylinositol phospholipase D activity Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol. MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN|Reactome:R-HSA-8940388|RHEA:10832|EC:3.1.4.50 go-plus.json phosphatidylinositol-glycan-specific phospholipase D activity|GPI-PLD activity|phosphatidylinositol phospholipase D activity|glycoprotein phospholipase D activity|phosphatidylinositol-specific phospholipase D activity|glycoprotein-phosphatidylinositol phosphatidohydrolase activity http://purl.obolibrary.org/obo/GO_0004621 CHEBI:137917 biolink:ChemicalSubstance 4-hydroxy-17beta-estradiol 4-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137917 CHEBI:137911 biolink:ChemicalSubstance 4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137911 PO:0025117 biolink:OntologyClass plant anatomical space An anatomical space that is part of a plant. go-plus.json lacunae (narrow)|lumen (narrow)|lumina (narrow)|lacuna (narrow)|espacio anatómico vegetal (Spanish, exact)|植物 解剖学（形態）的空間 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025117 GO:0004628 biolink:MolecularActivity obsolete calcium-independent cytosolic phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. go-plus.json calcium-independent cytosolic phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0004628 GO:0004627 biolink:MolecularActivity obsolete calcium-dependent cytosolic phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. go-plus.json calcium-dependent cytosolic phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0004627 GO:0004629 biolink:MolecularActivity phospholipase C activity Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate. Reactome:R-HSA-5362553|MetaCyc:PHOSPHOLIPASE-C-RXN|Reactome:R-HSA-399998|Reactome:R-HSA-114688|Reactome:R-HSA-114689|Reactome:R-HSA-398193|EC:3.1.4.3|Reactome:R-HSA-1112666 go-plus.json phosphatidase C|lecithinase C activity|lipophosphodiesterase C http://purl.obolibrary.org/obo/GO_0004629 GO:0004635 biolink:MolecularActivity phosphoribosyl-AMP cyclohydrolase activity Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide. MetaCyc:HISTCYCLOHYD-RXN|EC:3.5.4.19|RHEA:20049|KEGG_REACTION:R04037 go-plus.json 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity|phosphoribosyladenosine monophosphate cyclohydrolase activity|PRAMP-cyclohydrolase activity http://purl.obolibrary.org/obo/GO_0004635 GO:0004634 biolink:MolecularActivity phosphopyruvate hydratase activity Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O. MetaCyc:2PGADEHYDRAT-RXN|EC:4.2.1.11|Reactome:R-HSA-71660|RHEA:10164|Reactome:R-HSA-70494 go-plus.json gamma-enolase activity|2-phospho-D-glycerate-hydrolase activity|2-phospho-D-glycerate hydro-lyase activity|phosphoenolpyruvate hydratase activity|14-3-2-protein|enolase activity|2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)|nervous-system specific enolase|2-phosphoglyceric dehydratase activity|2-phosphoglycerate dehydratase activity|2-phosphoglycerate enolase activity http://purl.obolibrary.org/obo/GO_0004634 GO:0004637 biolink:MolecularActivity phosphoribosylamine-glycine ligase activity Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate. KEGG_REACTION:R04144|RHEA:17453|Reactome:R-HSA-73814|MetaCyc:GLYRIBONUCSYN-RXN|EC:6.3.4.13 go-plus.json 5-phospho-D-ribosylamine:glycine ligase (ADP-forming)|GAR synthetase activity|phosphoribosylglycineamide synthetase activity|GAR|GARS activity|glycinamide ribonucleotide synthetase activity|5'-phosphoribosylglycinamide synthetase activity|glycineamide ribonucleotide synthetase activity|phosphoribosylglycinamide synthetase activity|2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity http://purl.obolibrary.org/obo/GO_0004637 GO:0004636 biolink:MolecularActivity phosphoribosyl-ATP diphosphatase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+). MetaCyc:HISTPRATPHYD-RXN|RHEA:22828|EC:3.6.1.31|KEGG_REACTION:R04035 go-plus.json phosphoribosyladenosine triphosphate pyrophosphatase activity|1-(5-phosphoribosyl)-ATP diphosphohydrolase activity|phosphoribosyl-ATP pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0004636 GO:0004631 biolink:MolecularActivity phosphomevalonate kinase activity Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+). RHEA:16341|Reactome:R-HSA-191422|MetaCyc:PHOSPHOMEVALONATE-KINASE-RXN|KEGG_REACTION:R03245|EC:2.7.4.2 go-plus.json 5-phosphomevalonate kinase activity|mevalonate phosphate kinase activity|ATP:5-phosphomevalonate phosphotransferase activity|mevalonate-5-phosphate kinase activity|mevalonic acid phosphate kinase activity|ATP:(R)-5-phosphomevalonate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004631 GO:0004630 biolink:MolecularActivity phospholipase D activity Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate. Reactome:R-HSA-2029471|Reactome:R-HSA-1483142|Reactome:R-HSA-1483182|MetaCyc:PHOSCHOL-RXN|RHEA:14445|EC:3.1.4.4 go-plus.json lipophosphodiesterase II activity|lecithinase D activity|phosphatidylcholine phosphatidohydrolase activity|choline phosphatase activity http://purl.obolibrary.org/obo/GO_0004630 goslim_chembl GO:0004633 biolink:MolecularActivity phosphopantothenoylcysteine decarboxylase activity Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate. RHEA:16793|MetaCyc:P-PANTOCYSDECARB-RXN|Reactome:R-HSA-196840|EC:4.1.1.36|KEGG_REACTION:R03269 go-plus.json N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity|N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity|4-phosphopantothenoyl-L-cysteine decarboxylase activity|PPC-decarboxylase activity|N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)|4-phosphopantotheoylcysteine decarboxylase activity http://purl.obolibrary.org/obo/GO_0004633 GO:0004632 biolink:MolecularActivity phosphopantothenate--cysteine ligase activity Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives. RHEA:19397|Reactome:R-HSA-196753|MetaCyc:P-PANTOCYSLIG-RXN|EC:6.3.2.5 go-plus.json phosphopantothenoylcysteine synthetase activity|phosphopantothenate-cysteine ligase activity|(R)-4'-phosphopantothenate:L-cysteine ligase activity http://purl.obolibrary.org/obo/GO_0004632 CHEBI:137927 biolink:ChemicalSubstance CDP-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137927 chebi_ph7_3 CHEBI:137921 biolink:ChemicalSubstance lithocholic acid 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137921 CHEBI:137924 biolink:ChemicalSubstance 2-hydroxyestrone 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137924 CHEBI:137923 biolink:ChemicalSubstance 5'-end ribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137923 GO:0004639 biolink:MolecularActivity phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate. KEGG_REACTION:R04591|MetaCyc:SAICARSYN-RXN|RHEA:22628|Reactome:R-HSA-73805|EC:6.3.2.6 go-plus.json 4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity|5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity|SAICAR synthetase activity|phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity|phosphoribosylaminoimidazole-succinocarboxamide synthetase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)|4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity|PurC|SAICARs activity|SAICAR synthase activity|4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity|phosphoribosylaminoimidazole-succinocarboxamide synthase activity http://purl.obolibrary.org/obo/GO_0004639 GO:0004638 biolink:MolecularActivity phosphoribosylaminoimidazole carboxylase activity Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2). MetaCyc:AIRCARBOXY-RXN|KEGG_REACTION:R04209|EC:4.1.1.21|Reactome:R-HSA-73806|RHEA:10792 go-plus.json 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity|AIR carboxylase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]|ADE2|class II PurE|5-amino-1-ribosylimidazole 5-phosphate carboxylase activity|5-phosphoribosyl-5-aminoimidazole carboxylase activity|1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0004638 GO:0004602 biolink:MolecularActivity glutathione peroxidase activity Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O. Reactome:R-HSA-2161959|Reactome:R-HSA-2161999|Reactome:R-HSA-6799695|Reactome:R-HSA-3341277|Reactome:R-HSA-3341397|RHEA:16833|Reactome:R-HSA-3323013|Reactome:R-HSA-2161946|EC:1.11.1.9|Reactome:R-HSA-71676|Reactome:R-HSA-2161791|Reactome:R-HSA-3343700|MetaCyc:GLUTATHIONE-PEROXIDASE-RXN go-plus.json reduced glutathione peroxidase activity|non-selenium glutathione peroxidase activity|glutathione:hydrogen-peroxide oxidoreductase activity|selenium-glutathione peroxidase activity|GSH peroxidase activity http://purl.obolibrary.org/obo/GO_0004602 GO:0004601 biolink:MolecularActivity peroxidase activity Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O. EC:1.11.1.-|Reactome:R-HSA-1222346|Reactome:R-HSA-2559639|Reactome:R-HSA-6789126|Reactome:R-HSA-3341296|Reactome:R-HSA-140359|KEGG_REACTION:R03532|Reactome:R-HSA-6789031|MetaCyc:PEROXID-RXN|Reactome:R-HSA-209815|Reactome:R-HSA-2309773|Reactome:R-HSA-8855490|Reactome:R-HSA-5631885|Reactome:R-HSA-8933635|Reactome:R-HSA-350901|Reactome:R-HSA-209840|Reactome:R-HSA-209973|Reactome:R-HSA-209925 go-plus.json horseradish peroxidase (HRP)|protoheme peroxidase|lactoperoxidase activity|peroxidase reaction|scopoletin peroxidase|donor:hydrogen-peroxide oxidoreductase activity|secretory plant peroxidase activity|bacterial catalase-peroxidase activity|extensin peroxidase|MPO|myeloperoxidase activity|verdoperoxidase|heme peroxidase|thiocyanate peroxidase|guaiacol peroxidase|pyrocatechol peroxidase|oxyperoxidase activity|japanese radish peroxidase|eosinophil peroxidase activity http://purl.obolibrary.org/obo/GO_0004601 goslim_metagenomics GO:0004604 biolink:MolecularActivity phosphoadenylyl-sulfate reductase (thioredoxin) activity Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS. MetaCyc:1.8.4.8-RXN|RHEA:11724|EC:1.8.4.8|KEGG_REACTION:R02021 go-plus.json PAPS reductase, thioredoxin-dependent activity|phosphoadenosine-phosphosulfate reductase activity|adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|PAPS reductase activity|phosphoadenylyl-sulphate reductase (thioredoxin) activity|PAdoPS reductase activity|thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity|3'-phosphoadenylylsulfate reductase activity|PAPS sulfotransferase activity|adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|thioredoxin:3'-phospho-adenylylsulfate reductase activity http://purl.obolibrary.org/obo/GO_0004604 GO:0004603 biolink:MolecularActivity phenylethanolamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine. EC:2.1.1.28|MetaCyc:2.1.1.28-RXN|RHEA:12176|Reactome:R-HSA-209903 go-plus.json norepinephrine methyltransferase activity|norepinephrine N-methyltransferase activity|S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity|noradrenaline N-methyltransferase activity|phenethanolamine methyltransferase activity|phenethanolamine N-methyltransferase activity|noradrenalin N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0004603 GO:0004600 biolink:MolecularActivity obsolete cyclophilin OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity. go-plus.json cyclophilin http://purl.obolibrary.org/obo/GO_0004600 CHEBI:231086 biolink:ChemicalSubstance Octadec-9-enoic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_231086 CHEBI:300 biolink:ChemicalSubstance (R)-(+)-alpha-terpineol go-plus.json http://purl.obolibrary.org/obo/CHEBI_300 chebi_ph7_3 GO:0004609 biolink:MolecularActivity phosphatidylserine decarboxylase activity Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine. Reactome:R-HSA-1483212|RHEA:20828|EC:4.1.1.65|MetaCyc:PHOSPHASERDECARB-RXN|KEGG_REACTION:R02055 go-plus.json phosphatidyl-L-serine carboxy-lyase activity|phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)|PS decarboxylase activity http://purl.obolibrary.org/obo/GO_0004609 GO:0004606 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004606 GO:0004605 biolink:MolecularActivity phosphatidate cytidylyltransferase activity Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol. Reactome:R-HSA-1483121|Reactome:R-HSA-1483165|MetaCyc:CDPDIGLYSYN-RXN|RHEA:16229|EC:2.7.7.41 go-plus.json CDP diglyceride pyrophosphorylase activity|CDP-diglyceride synthetase activity|CTP:1,2-diacylglycerophosphate-cytidyl transferase activity|DAG synthetase activity|CTP-diacylglycerol synthetase activity|phosphatidic acid cytidylyltransferase activity|phosphatidate cytidyltransferase activity|CDP-DG|CDP-diacylglycerol synthase activity|CDP-diacylglyceride synthetase activity|cytidine diphosphoglyceride pyrophosphorylase activity|CTP:phosphatidate cytidylyltransferase activity|CDP-diglyceride synthase activity|CDP-diglyceride pyrophosphorylase activity|CDP-diglyceride diphosphorylase activity http://purl.obolibrary.org/obo/GO_0004605 UBERON:0006127 biolink:AnatomicalEntity funiculus of spinal cord A funiculus of neuraxis that is part of a spinal cord. go-plus.json spinal cord funiculus|white column of spinal cord http://purl.obolibrary.org/obo/UBERON_0006127 GO:0004608 biolink:MolecularActivity phosphatidylethanolamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine. EC:2.1.1.17|MetaCyc:2.1.1.17-RXN|KEGG_REACTION:R02056|RHEA:11164|Reactome:R-HSA-1483174 go-plus.json phosphatidylethanolamine-N-methylase activity|phosphatidylethanolamine methyltransferase activity|phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity|PEMT|S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity|lipid methyl transferase activity|LMTase activity http://purl.obolibrary.org/obo/GO_0004608 GO:0004607 biolink:MolecularActivity phosphatidylcholine-sterol O-acyltransferase activity Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine. Reactome:R-HSA-264695|RHEA:21204|EC:2.3.1.43|MetaCyc:2.3.1.43-RXN go-plus.json phospholipid--cholesterol acyltransferase activity|phosphatidylcholine:sterol O-acyltransferase activity|lecithin:cholesterol acyltransferase activity|LCAT (lecithin-cholesterol acyltransferase)|lecithin--cholesterol acyltransferase activity|LCAT activity http://purl.obolibrary.org/obo/GO_0004607 GO:0004613 biolink:MolecularActivity phosphoenolpyruvate carboxykinase (GTP) activity Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2. Reactome:R-HSA-70241|MetaCyc:4.1.1.32-RXN|Reactome:R-HSA-372819|EC:4.1.1.32|RHEA:10388 go-plus.json GTP:oxaloacetate carboxy-lyase (transphosphorylating)|phosphoenolpyruvate carboxylase (GTP)|phosphoenolpyruvic carboxykinase|phosphopyruvate (guanosine triphosphate) carboxykinase activity|phosphoenolpyruvic carboxylase (GTP)|phosphopyruvate carboxylase (GTP)|GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)|phosphoenolpyruvic carboxykinase (GTP) http://purl.obolibrary.org/obo/GO_0004613 GO:0004612 biolink:MolecularActivity phosphoenolpyruvate carboxykinase (ATP) activity Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate. EC:4.1.1.49|MetaCyc:PEPCARBOXYKIN-RXN|RHEA:18617|KEGG_REACTION:R00341 go-plus.json PEPK|ATP:oxaloacetate carboxy-lyase (transphosphorylating)|phosphoenolpyruvate carboxylase (ATP)|phosphoenolpyruvic carboxykinase|phosphopyruvate carboxykinase|phosphopyruvate carboxylase (ATP)|PEPCK (ATP)|ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphopyruvate carboxykinase (adenosine triphosphate) http://purl.obolibrary.org/obo/GO_0004612 GO:0004615 biolink:MolecularActivity phosphomannomutase activity Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. RHEA:11140|Reactome:R-HSA-3781926|Reactome:R-HSA-446201|MetaCyc:PHOSMANMUT-RXN|KEGG_REACTION:R01818|EC:5.4.2.8 go-plus.json alpha-D-mannose 1,6-phosphomutase activity|mannose phosphomutase activity|D-mannose 1,6-phosphomutase activity|phosphomannose mutase activity http://purl.obolibrary.org/obo/GO_0004615 GO:0004614 biolink:MolecularActivity phosphoglucomutase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. EC:5.4.2.2|Reactome:R-HSA-9638125|Reactome:R-HSA-5609939|Reactome:R-HSA-70272|Reactome:R-HSA-9638127|RHEA:23536|Reactome:R-HSA-70427|MetaCyc:PHOSPHOGLUCMUT-RXN go-plus.json glucose phosphomutase activity|phosphoglucose mutase activity|alpha-D-glucose 1,6-phosphomutase activity http://purl.obolibrary.org/obo/GO_0004614 GO:0004611 biolink:MolecularActivity phosphoenolpyruvate carboxykinase activity Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products. EC:4.1.1.32 go-plus.json PEPCK activity|phosphopyruvate carboxylase activity|PEP carboxykinase activity http://purl.obolibrary.org/obo/GO_0004611 GO:0004610 biolink:MolecularActivity phosphoacetylglucosamine mutase activity Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate. EC:5.4.2.3|KEGG_REACTION:R08193|MetaCyc:PHOSACETYLGLUCOSAMINEMUT-RXN|RHEA:23804|Reactome:R-HSA-446185 go-plus.json N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity|N-acetyl-D-glucosamine 1,6-phosphomutase activity|acetylaminodeoxyglucose phosphomutase activity|acetylglucosamine phosphomutase activity|N-acetylglucosamine-phosphate mutase activity|phospho-N-acetylglucosamine mutase activity http://purl.obolibrary.org/obo/GO_0004610 CHEBI:137907 biolink:ChemicalSubstance 2-hydroxy-17beta-estradiol 2-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137907 GO:0004617 biolink:MolecularActivity phosphoglycerate dehydrogenase activity Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+. RHEA:12641|Reactome:R-HSA-977348|MetaCyc:PGLYCDEHYDROG-RXN|EC:1.1.1.95 go-plus.json 3PHP reductase activity|glycerate-1,3-phosphate dehydrogenase activity|3-phosphoglycerate dehydrogenase activity|alpha-KG reductase activity|glycerate 3-phosphate dehydrogenase activity|D- and L-HGA|SerA|3-phosphoglycerate:NAD+ 2-oxidoreductase activity|D-3-phosphoglycerate dehydrogenase activity|alphaKG reductase activity|phosphoglycerate oxidoreductase activity|3-phosphoglyceric acid dehydrogenase activity|3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity|PGDH activity|alpha-phosphoglycerate dehydrogenase activity|SerA 3PG dehydrogenase activity|D-3-phosphoglycerate:NAD+ oxidoreductase activity|phosphoglyceric acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004617 GO:0004616 biolink:MolecularActivity phosphogluconate dehydrogenase (decarboxylating) activity Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+. Reactome:R-HSA-71299|EC:1.1.1.44|MetaCyc:6PGLUCONDEHYDROG-RXN|RHEA:10116 go-plus.json 6-phospho-D-gluconate dehydrogenase activity|6-phosphogluconic dehydrogenase activity|phosphogluconic acid dehydrogenase activity|6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)|6-phosphogluconate dehydrogenase (decarboxylating)|6PGD activity|6-phosphogluconic carboxylase activity http://purl.obolibrary.org/obo/GO_0004616 GO:0004619 biolink:MolecularActivity phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate. EC:5.4.2.1|Reactome:R-HSA-71445|Reactome:R-HSA-71654|MetaCyc:3PGAREARR-RXN|RHEA:15901 go-plus.json monophosphoglycerate mutase activity|GriP mutase|D-phosphoglycerate 2,3-phosphomutase activity|PGA mutase activity|phosphoglycerate phosphomutase activity|diphosphoglycomutase|phosphoglyceromutase activity|PGM|monophosphoglyceromutase activity|PGAM activity|bisphosphoglyceromutase|MPGM http://purl.obolibrary.org/obo/GO_0004619 GO:0004618 biolink:MolecularActivity phosphoglycerate kinase activity Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+). EC:2.7.2.3|Reactome:R-HSA-71850|MetaCyc:PHOSGLYPHOS-RXN|Reactome:R-HSA-70486|KEGG_REACTION:R01512|RHEA:14801 go-plus.json glycerate 3-phosphate kinase activity|3-phosphoglyceric kinase activity|3-phosphoglycerate kinase activity|ATP:D-3-phosphoglycerate 1-phosphotransferase activity|phosphoglyceric kinase activity|3-phosphoglycerate phosphokinase activity|3-PGK|phosphoglyceric acid kinase activity|glycerophosphate kinase activity|phosphoglycerokinase activity|PGK|3-phosphoglyceric acid kinase activity|3-phosphoglyceric acid phosphokinase activity|ATP-3-phospho-D-glycerate-1-phosphotransferase activity|ATP:3-phospho-D-glycerate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004618 PO:0025166 biolink:OntologyClass papilla cell An epidermal pavement cell with a short protuberance. go-plus.json 乳頭細胞 (Japanese, exact)|célula papilosa (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025166 PO:0025165 biolink:OntologyClass shoot epidermal cell An epidermal cell that is part of a shoot epidermis. go-plus.json célula epidérmica del epiblasto (epiblastema) (Spanish, exact)|シュート表皮 細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025165 PO:0025164 biolink:OntologyClass root epidermal cell An epidermal cell that is part of a root epidermis. go-plus.json 根表皮細胞 (Japanese, exact)|célula epidérmica de la raíz (Spanish, exact) http://purl.obolibrary.org/obo/PO_0025164 PO:0025162 biolink:OntologyClass multicellular trichome A portion of plant tissue (PO:0009007) that forms a non-sclerified outgrowth from the epidermis (PO:0005679). go-plus.json non-glandular multicelluar trichome (narrow)|non-secretory multicellular trichome (narrow)|tricoma multicelular (Spanish, exact)|多細胞毛（毛茸、糸状体） (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025162 PO:0025158 biolink:OntologyClass bract epidermis A portion of phyllome epidermis (PO:0025157) that is part of a bract (PO:0009055). go-plus.json epidermis de la bráctea (Spanish, exact)|苞表皮 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025158 PO:0025157 biolink:OntologyClass phyllome epidermis A portion of shoot system epidermis (PO:0006035) that is part of a phyllome (PO:0006001). go-plus.json epidermis del filoma (Spanish, exact)|フィロム表皮 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0025157 PR:000029968 biolink:Protein somatotropin hormone family member A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide. go-plus.json fam:GH1 http://purl.obolibrary.org/obo/PR_000029968 NCBITaxon:135461 biolink:OrganismalEntity Bacillus subtilis subsp. subtilis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_135461 CHEBI:147345 biolink:ChemicalSubstance (2S)-hydroperoxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_147345 CHEBI:147340 biolink:ChemicalSubstance (2R)-2-hydroperoxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_147340 chebi_ph7_3 CHEBI:147341 biolink:ChemicalSubstance fumigermin go-plus.json http://purl.obolibrary.org/obo/CHEBI_147341 chebi_ph7_3 CHEBI:147344 biolink:ChemicalSubstance (2R)-hydroperoxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_147344 CHEBI:147343 biolink:ChemicalSubstance 2-hydroperoxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_147343 GO:0038016 biolink:BiologicalProcess insulin receptor internalization A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell. go-plus.json insulin receptor endocytosis http://purl.obolibrary.org/obo/GO_0038016 GO:0014049 biolink:BiologicalProcess positive regulation of glutamate secretion Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. go-plus.json up-regulation of glutamate secretion|upregulation of glutamate secretion|up regulation of glutamate secretion|activation of glutamate secretion|stimulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014049 GO:0014048 biolink:BiologicalProcess regulation of glutamate secretion Any process that modulates the frequency, rate or extent of the controlled release of glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0014048 GO:0038015 biolink:BiologicalProcess positive regulation of insulin receptor signaling pathway by insulin receptor internalization Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane. go-plus.json positive regulation of insulin receptor signalling pathway by insulin receptor internalization http://purl.obolibrary.org/obo/GO_0038015 GO:0014047 biolink:BiologicalProcess glutamate secretion The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0014047 GO:0038018 biolink:BiologicalProcess Wnt receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. go-plus.json Frizzled degradation|Wnt receptor catabolism|negative regulation of Wnt receptor signaling pathway by Wnt receptor degradation|Wnt receptor degradation|Wnt receptor breakdown http://purl.obolibrary.org/obo/GO_0038018 GO:0014046 biolink:BiologicalProcess dopamine secretion The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0014046 GO:0038017 biolink:BiologicalProcess Wnt receptor internalization A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell. go-plus.json Wnt receptor endocytosis http://purl.obolibrary.org/obo/GO_0038017 GO:0038019 biolink:BiologicalProcess Wnt receptor recycling The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. go-plus.json Frizzled recycling http://purl.obolibrary.org/obo/GO_0038019 GO:0014041 biolink:BiologicalProcess regulation of neuron maturation Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. go-plus.json http://purl.obolibrary.org/obo/GO_0014041 GO:0014040 biolink:BiologicalProcess positive regulation of Schwann cell differentiation Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. go-plus.json upregulation of Schwann cell differentiation|stimulation of Schwann cell differentiation|up-regulation of Schwann cell differentiation|activation of Schwann cell differentiation|up regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0014040 GO:0038010 biolink:BiologicalProcess positive regulation of signal transduction by receptor internalization Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms. go-plus.json positive regulation of signaling pathway by receptor endocytosis http://purl.obolibrary.org/obo/GO_0038010 GO:0038012 biolink:BiologicalProcess negative regulation of Wnt signaling pathway by Wnt receptor internalization Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction. go-plus.json ligand-dependent internalization of Frizzled|negative regulation of Wnt receptor signalling pathway by Wnt receptor internalization|negative regulation of Wnt receptor signaling pathway by Wnt receptor endocytosis|negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization|negative regulation of Wnt-activated signaling pathway by Wnt receptor internalization http://purl.obolibrary.org/obo/GO_0038012 GO:0014045 biolink:BiologicalProcess establishment of endothelial blood-brain barrier Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. go-plus.json establishment of endothelial BBB|establishment of endothelial blood/brain barrier http://purl.obolibrary.org/obo/GO_0014045 GO:0014044 biolink:BiologicalProcess Schwann cell development The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. go-plus.json http://purl.obolibrary.org/obo/GO_0014044 GO:0038011 biolink:BiologicalProcess negative regulation of signal transduction by receptor internalization Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands. go-plus.json negative regulation of signaling pathway by receptor endocytosis http://purl.obolibrary.org/obo/GO_0038011 GO:0038014 biolink:BiologicalProcess negative regulation of insulin receptor signaling pathway by insulin receptor internalization Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation. go-plus.json agonist-stimulated insulin receptor internalization|negative regulation of insulin receptor signalling pathway by insulin receptor internalization http://purl.obolibrary.org/obo/GO_0038014 GO:0014043 biolink:BiologicalProcess negative regulation of neuron maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. go-plus.json down regulation of neuron maturation|downregulation of neuron maturation|down-regulation of neuron maturation|inhibition of neuron maturation http://purl.obolibrary.org/obo/GO_0014043 GO:0014042 biolink:BiologicalProcess positive regulation of neuron maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. go-plus.json upregulation of neuron maturation|up regulation of neuron maturation|activation of neuron maturation|stimulation of neuron maturation|up-regulation of neuron maturation http://purl.obolibrary.org/obo/GO_0014042 GO:0038013 biolink:BiologicalProcess positive regulation of Wnt signaling pathway by Wnt receptor internalization Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway. go-plus.json positive regulation of Wnt receptor signalling pathway by Wnt receptor endocytosis|positive regulation of Wnt receptor signaling pathway by Frizzled internalization|positive regulation of Wnt receptor signaling pathway by LRP6 internalization|positive regulation of Wnt-activated signaling pathway by Wnt receptor internalization|positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization http://purl.obolibrary.org/obo/GO_0038013 CHEBI:147335 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol-3-phosphate anion derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_147335 chebi_ph7_3 CHEBI:147334 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol anion derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_147334 chebi_ph7_3 GO:0038005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038005 GO:0038004 biolink:BiologicalProcess epidermal growth factor receptor ligand maturation Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor. go-plus.json peptide bond cleavage involved in epidermal growth factor receptor ligand maturation|peptide bond cleavage involved in EGFR ligand maturation|EGFR ligand maturation by peptide bond cleavage|EGFR ligand maturation|EGFR ligand processing|epidermal growth factor receptor ligand processing http://purl.obolibrary.org/obo/GO_0038004 GO:0014059 biolink:BiologicalProcess regulation of dopamine secretion Any process that modulates the frequency, rate or extent of the regulated release of dopamine. go-plus.json http://purl.obolibrary.org/obo/GO_0014059 GO:0038007 biolink:BiologicalProcess netrin-activated signaling pathway A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance. go-plus.json netrin-activated signalling pathway|netrin-mediated signaling pathway|netrin signaling pathway|netrin-activated signal transduction pathway http://purl.obolibrary.org/obo/GO_0038007 GO:0014058 biolink:BiologicalProcess negative regulation of acetylcholine secretion, neurotransmission Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine. go-plus.json down regulation of acetylcholine secretion|downregulation of acetylcholine secretion|down-regulation of acetylcholine secretion|inhibition of acetylcholine secretion http://purl.obolibrary.org/obo/GO_0014058 GO:0014057 biolink:BiologicalProcess positive regulation of acetylcholine secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine. go-plus.json upregulation of acetylcholine secretion|up regulation of acetylcholine secretion|activation of acetylcholine secretion|stimulation of acetylcholine secretion|up-regulation of acetylcholine secretion http://purl.obolibrary.org/obo/GO_0014057 GO:0038006 biolink:MolecularActivity netrin receptor activity involved in chemoattraction Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin. go-plus.json netrin receptor activity involved in positive chemotaxis|attractive netrin receptor activity http://purl.obolibrary.org/obo/GO_0038006 GO:0038009 biolink:BiologicalProcess regulation of signal transduction by receptor internalization Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway. go-plus.json regulation of signaling pathway by receptor endocytosis http://purl.obolibrary.org/obo/GO_0038009 GO:0038008 biolink:BiologicalProcess TRAF-mediated signal transduction The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components. go-plus.json tumor necrosis factor receptor-associated factor signaling|TRAF-mediated signalling|tumor necrosis factor receptor-associated factor signal transduction|TRAF signaling|TRAF-mediated intracellular signaling|TRAF-mediated signaling http://purl.obolibrary.org/obo/GO_0038008 GO:0014052 biolink:BiologicalProcess regulation of gamma-aminobutyric acid secretion Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. go-plus.json regulation of GABA secretion http://purl.obolibrary.org/obo/GO_0014052 GO:0014051 biolink:BiologicalProcess gamma-aminobutyric acid secretion The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. go-plus.json GABA secretion http://purl.obolibrary.org/obo/GO_0014051 GO:0014050 biolink:BiologicalProcess negative regulation of glutamate secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. go-plus.json downregulation of glutamate secretion|down-regulation of glutamate secretion|inhibition of glutamate secretion|down regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014050 GO:0038001 biolink:BiologicalProcess paracrine signaling The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other. go-plus.json paracrine signalling http://purl.obolibrary.org/obo/GO_0038001 GO:0014056 biolink:BiologicalProcess regulation of acetylcholine secretion, neurotransmission Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. go-plus.json http://purl.obolibrary.org/obo/GO_0014056 GO:0014055 biolink:BiologicalProcess acetylcholine secretion, neurotransmission The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). go-plus.json http://purl.obolibrary.org/obo/GO_0014055 GO:0038003 biolink:BiologicalProcess G protein-coupled opioid receptor signaling pathway The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands. Wikipedia:Opioid_receptor go-plus.json opioid receptor signaling pathway|opioid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0038003 GO:0014054 biolink:BiologicalProcess positive regulation of gamma-aminobutyric acid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. go-plus.json up regulation of gamma-aminobutyric acid secretion|activation of gamma-aminobutyric acid secretion|stimulation of gamma-aminobutyric acid secretion|up-regulation of gamma-aminobutyric acid secretion|positive regulation of GABA secretion|upregulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014054 GO:0038002 biolink:BiologicalProcess endocrine signaling The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other. go-plus.json endocrine signalling http://purl.obolibrary.org/obo/GO_0038002 GO:0014053 biolink:BiologicalProcess negative regulation of gamma-aminobutyric acid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. go-plus.json down regulation of gamma-aminobutyric acid secretion|downregulation of gamma-aminobutyric acid secretion|down-regulation of gamma-aminobutyric acid secretion|inhibition of gamma-aminobutyric acid secretion|negative regulation of GABA secretion http://purl.obolibrary.org/obo/GO_0014053 CHEBI:137998 biolink:ChemicalSubstance O-{S-[4-(gamma-L-glutamylamino)butanoyl]pantetheine-4'-phosphoryl}serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137998 chebi_ph7_3 GO:0014027 biolink:BiologicalProcess secondary neural tube rod cavitation The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube. go-plus.json medullary rod cavitation http://purl.obolibrary.org/obo/GO_0014027 CHEBI:137997 biolink:ChemicalSubstance O-[S-4-(aminobutanoyl)pantetheine-4'-phosphoryl]serine zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137997 chebi_ph7_3 GO:0014026 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0014026 CHEBI:137996 biolink:ChemicalSubstance O-[S-(gamma-L-glutamyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137996 chebi_ph7_3 GO:0014025 biolink:BiologicalProcess neural keel formation The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. go-plus.json http://purl.obolibrary.org/obo/GO_0014025 CHEBI:137995 biolink:ChemicalSubstance 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137995 chebi_ph7_3 GO:0014024 biolink:BiologicalProcess neural rod cavitation The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube. go-plus.json http://purl.obolibrary.org/obo/GO_0014024 GO:0014029 biolink:BiologicalProcess neural crest formation The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. go-plus.json http://purl.obolibrary.org/obo/GO_0014029 GO:0014028 biolink:BiologicalProcess notochord formation The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. go-plus.json http://purl.obolibrary.org/obo/GO_0014028 CHEBI:137999 biolink:ChemicalSubstance O-[S-4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137999 chebi_ph7_3 CHEBI:137990 biolink:ChemicalSubstance (beta-Asp-Arg)n-Asp(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137990 chebi_ph7_3 CHEBI:137994 biolink:ChemicalSubstance (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137994 chebi_ph7_3 GO:0014023 biolink:BiologicalProcess neural rod formation The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. go-plus.json http://purl.obolibrary.org/obo/GO_0014023 GO:0014022 biolink:BiologicalProcess neural plate elongation The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions. go-plus.json http://purl.obolibrary.org/obo/GO_0014022 GO:0014021 biolink:BiologicalProcess secondary neural tube formation The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals. go-plus.json neural rod formation|medullary cord formation|medullary cord biosynthesis|secondary neurulation http://purl.obolibrary.org/obo/GO_0014021 GO:0014020 biolink:BiologicalProcess primary neural tube formation The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. go-plus.json primary neurulation|primary neural tube morphogenesis http://purl.obolibrary.org/obo/GO_0014020 CHEBI:137991 biolink:ChemicalSubstance beta-Asp-Arg zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137991 chebi_ph7_3 GO:0014038 biolink:BiologicalProcess regulation of Schwann cell differentiation Any process that modulates the frequency, rate or extent of Schwann cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0014038 GO:0014037 biolink:BiologicalProcess Schwann cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. go-plus.json http://purl.obolibrary.org/obo/GO_0014037 GO:0014036 biolink:BiologicalProcess neural crest cell fate specification The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0014036 GO:0014035 biolink:BiologicalProcess neural crest cell fate determination The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0014035 GO:0014039 biolink:BiologicalProcess negative regulation of Schwann cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. go-plus.json down-regulation of Schwann cell differentiation|downregulation of Schwann cell differentiation|down regulation of Schwann cell differentiation|inhibition of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0014039 GO:0014030 biolink:BiologicalProcess mesenchymal cell fate commitment The process in which a cell becomes committed to become a mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014030 GO:0014034 biolink:BiologicalProcess neural crest cell fate commitment The process in which a cell becomes committed to become a neural crest cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014034 GO:0014033 biolink:BiologicalProcess neural crest cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014033 GO:0014032 biolink:BiologicalProcess neural crest cell development The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014032 GO:0014031 biolink:BiologicalProcess mesenchymal cell development The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. go-plus.json http://purl.obolibrary.org/obo/GO_0014031 GO:0004689 biolink:MolecularActivity phosphorylase kinase activity Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a. MetaCyc:2.7.11.19-RXN|EC:2.7.11.19|Reactome:R-HSA-453337|Reactome:R-HSA-71588|Reactome:R-HSA-71541 go-plus.json phosphorylase kinase (phosphorylating) activity|phosphorylase kinase, intrinsic catalyst activity|glycogen phosphorylase kinase activity|ATP:phosphorylase-b phosphotransferase activity|dephosphophosphorylase kinase activity|phosphorylase B kinase activity|PHK|STK17 http://purl.obolibrary.org/obo/GO_0004689 GO:0004686 biolink:MolecularActivity elongation factor-2 kinase activity Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate. MetaCyc:2.7.11.20-RXN|EC:2.7.11.20|RHEA:21436 go-plus.json eEF2K|EF2K|elongation factor 2 kinase activity|eEF2 kinase activity|Ca/CaM-kinase III activity|ATP:elongation factor 2 phosphotransferase activity|STK19|CaM kinase III activity|calmodulin-dependent protein kinase III activity|eEF-2 kinase activity|eukaryotic elongation factor 2 kinase activity http://purl.obolibrary.org/obo/GO_0004686 GO:0004685 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004685 GO:0004688 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004688 GO:0004687 biolink:MolecularActivity myosin light chain kinase activity Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate. RHEA:22004|MetaCyc:2.7.11.18-RXN|Reactome:R-HSA-5668978|EC:2.7.11.18|Reactome:R-HSA-445813 go-plus.json MLCK|smooth-muscle-myosin-light-chain kinase activity|MLCkase activity|myosin kinase activity|myosin light-chain kinase (phosphorylating) activity|myosin light-chain kinase|myosin light chain protein kinase activity|myosin-light-chain kinase activity|ATP:myosin-light-chain O-phosphotransferase|calcium/calmodulin-dependent myosin light chain kinase activity|ATP:myosin-light-chain O-phosphotransferase activity|STK18|myosin light-chain kinase (phosphorylating)|myosin light-chain kinase activity http://purl.obolibrary.org/obo/GO_0004687 NCBITaxon:16714 biolink:OrganismalEntity Juglandaceae go-plus.json walnut family http://purl.obolibrary.org/obo/NCBITaxon_16714 GO:0004682 biolink:MolecularActivity obsolete protein kinase CK2 activity OBSOLETE. Catalysis of the reaction: casein + ATP = phosphocasein + ADP. go-plus.json protein kinase CK2 activity|casein kinase II, catalytic activity|protein kinase CK2, intrinsic catalyst activity|casein kinase II activity http://purl.obolibrary.org/obo/GO_0004682 GO:0004681 biolink:MolecularActivity obsolete casein kinase I activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json casein kinase I activity http://purl.obolibrary.org/obo/GO_0004681 GO:0004684 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004684 GO:0004683 biolink:MolecularActivity calmodulin-dependent protein kinase activity Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. Reactome:R-HSA-9619355|Reactome:R-HSA-416320|MetaCyc:2.7.11.17-RXN|Reactome:R-HSA-9618750|EC:2.7.11.17|Reactome:R-HSA-9619125|Reactome:R-HSA-111912|Reactome:R-HSA-442749|Reactome:R-HSA-111915|Reactome:R-HSA-9619478|Reactome:R-HSA-9617583|Reactome:R-HSA-9619367|Reactome:R-HSA-9619783|Reactome:R-HSA-9006992 go-plus.json Ca2+/calmodulin-dependent protein kinase kinase beta activity|multifunctional calcium- and calmodulin-regulated protein kinase activity|calmodulin-dependent protein kinase I activity|microtubule-associated protein 2 kinase activity|Ca2+/calmodulin-dependent protein kinase 1 activity|Ca2+/calmodulin-dependent protein kinase II activity|CaMKKbeta|Ca2+/calmodulin-dependent protein kinase kinase activity|CaMKII|CaM kinase activity|calmodulin-dependent kinase II activity|ATP:caldesmon O-phosphotransferase activity|calcium/calmodulin-dependent protein kinase type II activity|CaM-regulated serine/threonine kinase activity|multifunctional calcium/calmodulin regulated protein kinase activity|calcium/calmodulin-dependent protein kinase activity|calmodulin regulated protein kinase activity|Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity|Ca2+/calmodulin-dependent protein kinase IV activity|caldesmon kinase (phosphorylating) activity|ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity|calcium- and calmodulin-dependent protein kinase activity|CaMKKalpha|CaMKI|CaM kinase II activity|Ca2+/CaM-dependent kinase activity|CAM PKII|Ca2+/calmodulin-dependent protein kinase activity|CaMKIV|STK20 http://purl.obolibrary.org/obo/GO_0004683 NCBITaxon:16718 biolink:OrganismalEntity Juglans go-plus.json walnuts http://purl.obolibrary.org/obo/NCBITaxon_16718 GO:0004680 biolink:MolecularActivity obsolete casein kinase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json casein kinase activity http://purl.obolibrary.org/obo/GO_0004680 CHEBI:137976 biolink:ChemicalSubstance S-acetyl-O-[2'-(5-phosphoribosyl)-3'-dephospho-CoA]-L-serine(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137976 chebi_ph7_3 GO:0014005 biolink:BiologicalProcess microglia development The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json microglial cell development http://purl.obolibrary.org/obo/GO_0014005 GO:0014004 biolink:BiologicalProcess microglia differentiation The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. go-plus.json microglial cell differentiation http://purl.obolibrary.org/obo/GO_0014004 GO:0014003 biolink:BiologicalProcess oligodendrocyte development The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. go-plus.json oligodendrocyte cell development http://purl.obolibrary.org/obo/GO_0014003 GO:0014002 biolink:BiologicalProcess astrocyte development The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. go-plus.json astrocyte cell development http://purl.obolibrary.org/obo/GO_0014002 GO:0014009 biolink:BiologicalProcess glial cell proliferation The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. go-plus.json glia proliferation http://purl.obolibrary.org/obo/GO_0014009 GO:0014008 biolink:BiologicalProcess positive regulation of microglia differentiation Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. go-plus.json positive regulation of microglial cell differentiation|up-regulation of microglia differentiation|upregulation of microglia differentiation|up regulation of microglia differentiation|activation of microglia differentiation|stimulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0014008 CHEBI:137979 biolink:ChemicalSubstance D-galactosylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137979 GO:0014007 biolink:BiologicalProcess negative regulation of microglia differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. go-plus.json inhibition of microglia differentiation|negative regulation of microglial cell differentiation|down regulation of microglia differentiation|downregulation of microglia differentiation|down-regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0014007 GO:0014006 biolink:BiologicalProcess regulation of microglia differentiation Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. go-plus.json regulation of microglial cell differentiation http://purl.obolibrary.org/obo/GO_0014006 CHEBI:147309 biolink:ChemicalSubstance diarachidonoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_147309 chebi_ph7_3 GO:0014001 biolink:BiologicalProcess sclerenchyma cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable. go-plus.json http://purl.obolibrary.org/obo/GO_0014001 GO:0004697 biolink:MolecularActivity protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol. Reactome:R-HSA-5625784|Reactome:R-HSA-1433508|Reactome:R-HSA-198314|Reactome:R-HSA-5623667|Reactome:R-HSA-429698|Reactome:R-HSA-450550|Reactome:R-HSA-2179413|Reactome:R-HSA-450533|Reactome:R-HSA-9010681|Reactome:R-HSA-5218823|Reactome:R-HSA-9632858|Reactome:R-HSA-9021357|Reactome:R-HSA-5218805|Reactome:R-HSA-374664|Reactome:R-HSA-927889|Reactome:R-HSA-909552|Reactome:R-HSA-8934446|Reactome:R-HSA-751040|Reactome:R-HSA-2730863|Reactome:R-HSA-5671749|Reactome:R-HSA-9626817|Reactome:R-HSA-5229194|MetaCyc:2.7.11.13-RXN|Reactome:R-HSA-5138432|Reactome:R-HSA-74615|EC:2.7.11.13|Reactome:R-HSA-193703 go-plus.json protein kinase Cepsilon activity|nPKCepsilon|PKCdelta|diacylglycerol-activated phospholipid-dependent protein kinase C activity|diacylglycerol-activated phospholipid-dependent PKC activity|STK24|PKC|Pkc1p|cPKC|nPKCtheta|PKCepsilon|cPKCgamma|PKCzeta|PKCgamma|nPKCdelta|PKC activity|nPKC|ATP:protein phosphotransferase (diacylglycerol-dependent) activity|cPKCalpha|PKCbeta|nPKCeta|PKCalpha|cPKCbeta http://purl.obolibrary.org/obo/GO_0004697 GO:0004696 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004696 GO:0004699 biolink:MolecularActivity calcium-independent protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium. Reactome:R-HSA-5607740 go-plus.json calcium-independent PKC activity|novel protein kinase C activity http://purl.obolibrary.org/obo/GO_0004699 GO:0004698 biolink:MolecularActivity calcium-dependent protein kinase C activity Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. Reactome:R-HSA-416639|Reactome:R-HSA-114684|Reactome:R-HSA-421007|EC:2.7.11.13|Reactome:R-HSA-114683 go-plus.json conventional protein kinase C activity|calcium-dependent PKC activity http://purl.obolibrary.org/obo/GO_0004698 GO:0004693 biolink:MolecularActivity cyclin-dependent protein serine/threonine kinase activity Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Reactome:R-HSA-5692755|Reactome:R-HSA-2245218|Reactome:R-HSA-380278|Reactome:R-HSA-68944|Reactome:R-HSA-9008412|Reactome:R-HSA-2468293|Reactome:R-HSA-180047|Reactome:R-HSA-2984220|Reactome:R-HSA-6793661|Reactome:R-HSA-2990882|Reactome:R-HSA-3788705|Reactome:R-HSA-187916|Reactome:R-HSA-9686521|Reactome:R-HSA-1912391|Reactome:R-HSA-2468287|Reactome:R-HSA-9009282|Reactome:R-HSA-69227|Reactome:R-HSA-174251|Reactome:R-HSA-5244669|Reactome:R-HSA-4086410|Reactome:R-HSA-187959|Reactome:R-HSA-4088024|Reactome:R-HSA-2172183|Reactome:R-HSA-2220971|MetaCyc:2.7.11.22-RXN|Reactome:R-HSA-6805109|Reactome:R-HSA-6797606|Reactome:R-HSA-1226095|Reactome:R-HSA-2430533|Reactome:R-HSA-187948|Reactome:R-HSA-2294600|Reactome:R-HSA-69005|Reactome:R-HSA-5195402|Reactome:R-HSA-9624800|Reactome:R-HSA-174132|Reactome:R-HSA-69756|Reactome:R-HSA-1226094|EC:2.7.11.22|Reactome:R-HSA-2514854|Reactome:R-HSA-188390|Reactome:R-HSA-174079|Reactome:R-HSA-187520|Reactome:R-HSA-69754|Reactome:R-HSA-174122 go-plus.json cyclin-dependent protein kinase activity|CDK|neuronal cdc2-like kinase activity|cyclin-dependent kinase-2 activity|cyclin D-cdk6 kinase activity|cdc2 kinase activity|cyclin-dependent kinase-4 activity|CDK, catalytic subunit activity|cyclin-A associated kinase activity|ATP:cyclin phosphotransferase activity|Cdk-activating protein kinase activity|cdk-activating kinase activity|cyclin E kinase activity|cyclin-dependent kinase activity|CDK activity|D-type cyclin kinase activity|cyclin-dependent kinase 6 activity|cyclin D-dependent kinase activity|cyclin-dependent protein kinase, intrinsic catalyst activity http://purl.obolibrary.org/obo/GO_0004693 GO:0004692 biolink:MolecularActivity cGMP-dependent protein kinase activity cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. Reactome:R-HSA-418442|MetaCyc:2.7.11.12-RXN|Reactome:R-HSA-1475422|Reactome:R-HSA-1497853|Reactome:R-HSA-418549|EC:2.7.11.12 go-plus.json ATP:protein phosphotransferase (cGMP-dependent) activity|PKG 1beta|PKG|STK23|guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity|PKG 1alpha|3':5'-cyclic GMP-dependent protein kinase activity|PKG II|cGMP-dependent protein kinase ibeta activity http://purl.obolibrary.org/obo/GO_0004692 GO:0004695 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004695 GO:0004694 biolink:MolecularActivity eukaryotic translation initiation factor 2alpha kinase activity Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0004694 CHEBI:7719 biolink:ChemicalSubstance ochratoxin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_7719 GO:0004691 biolink:MolecularActivity cAMP-dependent protein kinase activity cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. Reactome:R-HSA-5687088|Reactome:R-HSA-5610741|Reactome:R-HSA-5610720|Reactome:R-HSA-913451|Reactome:R-HSA-432232|Reactome:R-HSA-163773|Reactome:R-HSA-177284|Reactome:R-HSA-163676|Reactome:R-HSA-5617182|Reactome:R-HSA-177275|MetaCyc:2.7.11.11-RXN|Reactome:R-HSA-5617179|EC:2.7.11.11|Reactome:R-HSA-5610717|Reactome:R-HSA-163672 go-plus.json cAMP-dependent protein kinase, intrinsic catalyst activity|3',5' cAMP-dependent protein kinase activity|STK22|PKA C|ATP:protein phosphotransferase (cAMP-dependent) activity|protein kinase A activity|AMPK|PKA|3',5'-cAMP-dependent protein kinase activity|adenosine 3',5'-cyclophosphate-dependent protein kinase activity|cyclic AMP-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_0004691 GO:0004690 biolink:MolecularActivity cyclic nucleotide-dependent protein kinase activity cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0004690 GO:0014016 biolink:BiologicalProcess neuroblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. go-plus.json http://purl.obolibrary.org/obo/GO_0014016 CHEBI:137987 biolink:ChemicalSubstance 19-hydroxyprostaglandin I2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137987 chebi_ph7_3 GO:0014015 biolink:BiologicalProcess positive regulation of gliogenesis Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. go-plus.json upregulation of gliogenesis|up regulation of gliogenesis|activation of gliogenesis|stimulation of gliogenesis|up-regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014015 CHEBI:137986 biolink:ChemicalSubstance (beta-Asp-Arg)n zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137986 chebi_ph7_3 GO:0014014 biolink:BiologicalProcess negative regulation of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. go-plus.json down regulation of gliogenesis|downregulation of gliogenesis|down-regulation of gliogenesis|inhibition of gliogenesis http://purl.obolibrary.org/obo/GO_0014014 GO:0014013 biolink:BiologicalProcess regulation of gliogenesis Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. go-plus.json http://purl.obolibrary.org/obo/GO_0014013 CHEBI:137984 biolink:ChemicalSubstance methylated secondary ammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137984 chebi_ph7_3 GO:0014019 biolink:BiologicalProcess neuroblast development The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0014019 GO:0014018 biolink:BiologicalProcess neuroblast fate specification The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0014018 GO:0014017 biolink:BiologicalProcess neuroblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast. go-plus.json http://purl.obolibrary.org/obo/GO_0014017 CHEBI:137983 biolink:ChemicalSubstance methylated tertiary amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137983 chebi_ph7_3 GO:0014012 biolink:BiologicalProcess peripheral nervous system axon regeneration The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury. go-plus.json axon regeneration in peripheral nervous system http://purl.obolibrary.org/obo/GO_0014012 CHEBI:137982 biolink:ChemicalSubstance tertiary ammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137982 chebi_ph7_3 GO:0014011 biolink:BiologicalProcess Schwann cell proliferation involved in axon regeneration The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0014011 CHEBI:137981 biolink:ChemicalSubstance 5-amino-1-(5-phosphonato-beta-D-ribosyl)imidazol-3-ium go-plus.json http://purl.obolibrary.org/obo/CHEBI_137981 chebi_ph7_3 GO:0014010 biolink:BiologicalProcess Schwann cell proliferation The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0014010 CHEBI:137980 biolink:ChemicalSubstance metalloid atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_137980 GO:0004668 biolink:MolecularActivity protein-arginine deiminase activity Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3. This reaction is calcium-dependent. EC:3.5.3.15|RHEA:18089|Reactome:R-HSA-1183128|Reactome:R-HSA-3247569|MetaCyc:PROTEIN-ARGININE-DEIMINASE-RXN go-plus.json protein-L-arginine iminohydrolase activity|peptidylarginine deiminase activity http://purl.obolibrary.org/obo/GO_0004668 GO:0004667 biolink:MolecularActivity prostaglandin-D synthase activity Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2). RHEA:10600|KEGG_REACTION:R02266|Reactome:R-HSA-2161701|Reactome:R-HSA-2161620|MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN|EC:5.3.99.2 go-plus.json prostaglandin-R-prostaglandin D isomerase activity|(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity|prostaglandin-H2 D-isomerase activity|prostaglandin D2 synthase activity|PGH-PGD isomerase activity|PGD2 synthase activity http://purl.obolibrary.org/obo/GO_0004667 GO:0004664 biolink:MolecularActivity prephenate dehydratase activity Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2. MetaCyc:PREPHENATEDEHYDRAT-RXN|EC:4.2.1.51|RHEA:21648 go-plus.json prephenate hydro-lyase (decarboxylating)|prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming) http://purl.obolibrary.org/obo/GO_0004664 GO:0004663 biolink:MolecularActivity Rab geranylgeranyltransferase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. EC:2.5.1.60|MetaCyc:RXN-3701|MetaCyc:2.5.1.60-RXN go-plus.json type II protein geranyl-geranyltransferase activity|GGTaseII activity|geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|GGTase-II activity|Rab-protein geranylgeranyltransferase activity|protein geranylgeranyltransferase type II activity|RabGGTase activity http://purl.obolibrary.org/obo/GO_0004663 GO:0004666 biolink:MolecularActivity prostaglandin-endoperoxide synthase activity Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. MetaCyc:PROSTAGLANDIN-ENDOPEROXIDE-SYNTHASE-RXN|Reactome:R-HSA-140355|Reactome:R-HSA-2309787|EC:1.14.99.1|RHEA:23728 go-plus.json prostaglandin endoperoxide synthetase activity|(PG)H synthase activity|prostaglandin synthetase activity|fatty acid cyclooxygenase activity|PG synthetase activity|(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity|prostaglandin synthase activity|prostaglandin G/H synthase activity http://purl.obolibrary.org/obo/GO_0004666 GO:0004665 biolink:MolecularActivity prephenate dehydrogenase (NADP+) activity Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH. KEGG_REACTION:R01730|RHEA:21640|MetaCyc:PREPHENATE-DEHYDROGENASE-NADP+-RXN|EC:1.3.1.13 go-plus.json prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|prephenate:NADP+ oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0004665 GO:0004660 biolink:MolecularActivity protein farnesyltransferase activity Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate. RHEA:13345|MetaCyc:2.5.1.58-RXN|Reactome:R-HSA-2530501|Reactome:R-HSA-9647978|EC:2.5.1.58 go-plus.json CAAX farnesyltransferase activity|farnesyl-diphosphate:protein-cysteine farnesyltransferase activity|FTase activity|protein-cysteine farnesyltransferase activity http://purl.obolibrary.org/obo/GO_0004660 GO:0004662 biolink:MolecularActivity CAAX-protein geranylgeranyltransferase activity Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families. MetaCyc:RXN-3701|MetaCyc:2.5.1.60-RXN|EC:2.5.1.59 go-plus.json GGTaseI activity|geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|type I protein geranyl-geranyltransferase activity|geranylgeranyltransferase type I activity|GGTase-I activity|protein geranylgeranyltransferase type I http://purl.obolibrary.org/obo/GO_0004662 GO:0004661 biolink:MolecularActivity protein geranylgeranyltransferase activity Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein. go-plus.json protein-cysteine geranylgeranyltransferase activity http://purl.obolibrary.org/obo/GO_0004661 CHEBI:137954 biolink:ChemicalSubstance N(6)-[(E)-but-2-enoyl]-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137954 chebi_ph7_3 CHEBI:137952 biolink:ChemicalSubstance UDP-2,3-diacyl-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137952 CHEBI:137955 biolink:ChemicalSubstance N(6)-butyryl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137955 chebi_ph7_3 CHEBI:137950 biolink:ChemicalSubstance O(3)-(beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl)-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137950 chebi_ph7_3 GO:0004679 biolink:MolecularActivity AMP-activated protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP. EC:2.7.11.11|Reactome:R-HSA-5673768|Reactome:R-HSA-6805470|Reactome:R-HSA-200423|Reactome:R-HSA-1592244|Reactome:R-HSA-447074|Reactome:R-HSA-163691|Reactome:R-HSA-380927 go-plus.json AMPK activity|5'-AMP-activated protein kinase activity|SNF1A/AMP-activated protein kinase activity http://purl.obolibrary.org/obo/GO_0004679 GO:0004678 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004678 GO:0004675 biolink:MolecularActivity transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Reactome:R-HSA-198732|EC:2.7.11.30|Reactome:R-HSA-170868|RHEA:18673|Reactome:R-HSA-201476|MetaCyc:2.7.11.30-RXN go-plus.json receptor serine/threonine protein kinase activity|receptor protein serine/threonine kinase activity http://purl.obolibrary.org/obo/GO_0004675 GO:0004674 biolink:MolecularActivity protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Reactome:R-HSA-5357831|Reactome:R-HSA-165766|Reactome:R-HSA-165726|Reactome:R-HSA-9610153|Reactome:R-HSA-5635841|Reactome:R-HSA-3857328|Reactome:R-HSA-166286|Reactome:R-HSA-5683801|Reactome:R-HSA-211164|Reactome:R-HSA-5692779|Reactome:R-HSA-5624473|Reactome:R-HSA-198731|Reactome:R-HSA-202459|Reactome:R-HSA-195283|Reactome:R-HSA-450325|Reactome:R-HSA-2400001|Reactome:R-HSA-3371567|Reactome:R-HSA-6805285|Reactome:R-HSA-448955|Reactome:R-HSA-9683664|Reactome:R-HSA-5610718|Reactome:R-HSA-2430535|Reactome:R-HSA-8948039|Reactome:R-HSA-2028679|Reactome:R-HSA-5632672|Reactome:R-HSA-3222006|Reactome:R-HSA-8878054|Reactome:R-HSA-381091|Reactome:R-HSA-200421|Reactome:R-HSA-5674496|Reactome:R-HSA-109822|Reactome:R-HSA-9633008|Reactome:R-HSA-165758|Reactome:R-HSA-1549526|Reactome:R-HSA-199299|Reactome:R-HSA-5357477|Reactome:R-HSA-1168635|Reactome:R-HSA-2396007|Reactome:R-HSA-202222|Reactome:R-HSA-6801675|Reactome:R-HSA-209087|Reactome:R-HSA-5607732|Reactome:R-HSA-2028589|Reactome:R-HSA-442739|Reactome:R-HSA-446701|Reactome:R-HSA-6802935|Reactome:R-HSA-432110|Reactome:R-HSA-5684096|Reactome:R-HSA-9648883|Reactome:R-HSA-442832|Reactome:R-HSA-9032751|Reactome:R-HSA-5682026|Reactome:R-HSA-2028673|Reactome:R-HSA-5693540|Reactome:R-HSA-399950|Reactome:R-HSA-1362270|Reactome:R-HSA-5357472|Reactome:R-HSA-199935|Reactome:R-HSA-975874|Reactome:R-HSA-9013978|Reactome:R-HSA-2029454|Reactome:R-HSA-198371|Reactome:R-HSA-9612980|Reactome:R-HSA-8868567|Reactome:R-HSA-8878050|Reactome:R-HSA-9627089|Reactome:R-HSA-9648089|Reactome:R-HSA-170126|Reactome:R-HSA-109862|Reactome:R-HSA-199917|Reactome:R-HSA-198599|Reactome:R-HSA-2028555|Reactome:R-HSA-5685156|Reactome:R-HSA-8856813|Reactome:R-HSA-5218814|Reactome:R-HSA-3769394|Reactome:R-HSA-5260201|Reactome:R-HSA-5686578|Reactome:R-HSA-8940100|Reactome:R-HSA-8853419|Reactome:R-HSA-2730876|Reactome:R-HSA-75820|Reactome:R-HSA-2399969|Reactome:R-HSA-5672828|Reactome:R-HSA-156678|RHEA:46608|Reactome:R-HSA-2028598|Reactome:R-HSA-399951|Reactome:R-HSA-6805276|Reactome:R-HSA-2060328|Reactome:R-HSA-5687094|Reactome:R-HSA-419644|Reactome:R-HSA-195318|Reactome:R-HSA-975865|Reactome:R-HSA-2028675|Reactome:R-HSA-5672973|Reactome:R-HSA-5218916|Reactome:R-HSA-166284|Reactome:R-HSA-202500|Reactome:R-HSA-5672010|Reactome:R-HSA-75028|Reactome:R-HSA-1445144|Reactome:R-HSA-2990880|Reactome:R-HSA-2029469|Reactome:R-HSA-3857329|Reactome:R-HSA-450827|Reactome:R-HSA-202437|Reactome:R-HSA-419087|Reactome:R-HSA-8942836|Reactome:R-HSA-1168641|Reactome:R-HSA-451152|Reactome:R-HSA-419083|Reactome:R-HSA-5690250|Reactome:R-HSA-1168638|Reactome:R-HSA-188350|EC:2.7.11.1|Reactome:R-HSA-6811454|Reactome:R-HSA-111919|Reactome:R-HSA-163418|Reactome:R-HSA-1449597|Reactome:R-HSA-193647|Reactome:R-HSA-176298|Reactome:R-HSA-4332358|Reactome:R-HSA-198613|Reactome:R-HSA-6802943|Reactome:R-HSA-8854908|Reactome:R-HSA-193705|Reactome:R-HSA-5632670|Reactome:R-HSA-1181156|Reactome:R-HSA-5693598|Reactome:R-HSA-109860|Reactome:R-HSA-3858480|Reactome:R-HSA-1458463|Reactome:R-HSA-170087|Reactome:R-HSA-392752|Reactome:R-HSA-8853444|Reactome:R-HSA-6805479|Reactome:R-HSA-3772435|Reactome:R-HSA-975861|Reactome:R-HSA-399952|Reactome:R-HSA-399944|Reactome:R-HSA-5610722|Reactome:R-HSA-9673346|Reactome:R-HSA-5679205|Reactome:R-HSA-5683792|Reactome:R-HSA-9694293|Reactome:R-HSA-2399966|Reactome:R-HSA-5687090|Reactome:R-HSA-170076|Reactome:R-HSA-198669|Reactome:R-HSA-4793911|Reactome:R-HSA-2529020|Reactome:R-HSA-8868344|Reactome:R-HSA-164151|Reactome:R-HSA-9032863|Reactome:R-HSA-8868573|Reactome:R-HSA-5668947|Reactome:R-HSA-9008480|Reactome:R-HSA-8933446|Reactome:R-HSA-8850945|Reactome:R-HSA-2028583|Reactome:R-HSA-5683425|Reactome:R-HSA-448948|Reactome:R-HSA-6805103|Reactome:R-HSA-5666160|Reactome:R-HSA-8868118|Reactome:R-HSA-5672008|Reactome:R-HSA-5624492|Reactome:R-HSA-6805126|Reactome:R-HSA-166119|Reactome:R-HSA-912470|Reactome:R-HSA-3000310|Reactome:R-HSA-6804276|Reactome:R-HSA-429016|Reactome:R-HSA-5692768|Reactome:R-HSA-8868666|Reactome:R-HSA-5686704|Reactome:R-HSA-2399988|Reactome:R-HSA-9632868|Reactome:R-HSA-5685242|Reactome:R-HSA-5693536|Reactome:R-HSA-3371435|Reactome:R-HSA-165162|Reactome:R-HSA-9009208|Reactome:R-HSA-442724|Reactome:R-HSA-450499|Reactome:R-HSA-156682|Reactome:R-HSA-1592233|Reactome:R-HSA-5671763|Reactome:R-HSA-199839|Reactome:R-HSA-9645535|Reactome:R-HSA-2028670|Reactome:R-HSA-198609|Reactome:R-HSA-5687101|Reactome:R-HSA-109702|Reactome:R-HSA-199929|Reactome:R-HSA-419197|Reactome:R-HSA-3132737|Reactome:R-HSA-6804955|Reactome:R-HSA-198621|Reactome:R-HSA-5692775|Reactome:R-HSA-4332363|Reactome:R-HSA-5607742|Reactome:R-HSA-3249371|Reactome:R-HSA-198347|Reactome:R-HSA-2294580|RHEA:17989|Reactome:R-HSA-9008822|Reactome:R-HSA-2562526|Reactome:R-HSA-2399985|Reactome:R-HSA-201677|Reactome:R-HSA-3000327|Reactome:R-HSA-4411402|Reactome:R-HSA-8852306|Reactome:R-HSA-3928608|Reactome:R-HSA-2399941|Reactome:R-HSA-9656215|Reactome:R-HSA-3928577|Reactome:R-HSA-2399996|Reactome:R-HSA-156699|Reactome:R-HSA-6795290|Reactome:R-HSA-202541|Reactom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go-plus.json protein-serine kinase activity|threonine-specific protein kinase activity|serine/threonine protein kinase activity|serine protein kinase activity|serine-specific protein kinase activity|protein phosphokinase activity|protein serine-threonine kinase activity|serine kinase activity|protein serine kinase activity|protein threonine kinase activity|protein kinase (phosphorylating) activity|serine(threonine) protein kinase activity http://purl.obolibrary.org/obo/GO_0004674 GO:0004677 biolink:MolecularActivity DNA-dependent protein kinase activity DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0004677 GO:0004676 biolink:MolecularActivity 3-phosphoinositide-dependent protein kinase activity Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. Reactome:R-HSA-437195 go-plus.json PDK activity|phosphatidylinositol-3-phosphate protein kinase activity http://purl.obolibrary.org/obo/GO_0004676 GO:0004671 biolink:MolecularActivity protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester. Reactome:R-HSA-6788650|RHEA:21672|Reactome:R-HSA-9647977|KEGG_REACTION:R04496|MetaCyc:2.1.1.100-RXN|EC:2.1.1.100 go-plus.json prenylated protein carboxyl methyltransferase activity|S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity|isoprenylated protein methyltransferase activity|prenylcysteine carboxyl methyltransferase activity|farnesylated protein C-terminal O-methyltransferase activity|protein-S-isoprenylcysteine O-methyltransferase activity|S-farnesylcysteine methyltransferase activity|protein S-farnesylcysteine C-terminal methyltransferase activity|prenylcysteine carboxylmethyltransferase activity|protein C-terminal farnesylcysteine O-methyltransferase activity|isoprenylcysteine carboxylmethyltransferase activity|farnesyl cysteine C-terminal methyltransferase activity|prenylcysteine carboxymethyltransferase activity|prenylcysteine methyltransferase activity|farnesyl-protein carboxymethyltransferase activity|prenylated protein methyltransferase activity http://purl.obolibrary.org/obo/GO_0004671 CHEBI:43577 biolink:ChemicalSubstance 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43577 GO:0004673 biolink:MolecularActivity protein histidine kinase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine. EC:2.7.13.3|MetaCyc:2.7.13.3-RXN go-plus.json HP165|histidine kinase (ambiguous)|histidine protein kinase (ambiguous)|protein histidine kinase (ambiguous)|Sln1p|ATP:protein-L-histidine N-phosphotransferase activity|histidine kinase activity|EnvZ|protein kinase (histidine) (ambiguous)|histidine protein kinase activity|protein-histidine kinase activity|protein kinase (histidine)|HK1 http://purl.obolibrary.org/obo/GO_0004673 GO:0004672 biolink:MolecularActivity protein kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. Reactome:R-HSA-9673284|Reactome:R-HSA-9604606|MetaCyc:PROTEIN-KINASE-RXN|Reactome:R-HSA-975139|Reactome:R-HSA-156832|Reactome:R-HSA-937034 go-plus.json protamine kinase activity http://purl.obolibrary.org/obo/GO_0004672 goslim_candida|goslim_aspergillus CHEBI:43572 biolink:ChemicalSubstance kojic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43572 chebi_ph7_3 CHEBI:137965 biolink:ChemicalSubstance 4-methoxyestrone 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137965 PR:000005932 biolink:Protein granulocyte colony-stimulating factor A protein that is a translation product of the human CSF3 gene or a 1:1 ortholog thereof. go-plus.json G-CSF|pluripoietin|Csfg|GCSF|lenograstim|CSF3|filgrastim http://purl.obolibrary.org/obo/PR_000005932 PR:000005931 biolink:Protein granulocyte-macrophage colony-stimulating factor A protein that is a translation product of the human CSF2 gene or a 1:1 ortholog thereof. go-plus.json GM-CSF|colony-stimulating factor|GMCSF|CSF2|sargramostim|Csfgm|CSF|molgramostin http://purl.obolibrary.org/obo/PR_000005931 CHEBI:137967 biolink:ChemicalSubstance N(6)-acyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137967 chebi_ph7_3 CHEBI:137966 biolink:ChemicalSubstance 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137966 CHEBI:137961 biolink:ChemicalSubstance 4-hydroxyestrone 4-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137961 CHEBI:137960 biolink:ChemicalSubstance 4-hydroxyestrone 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137960 CHEBI:28726 biolink:ChemicalSubstance 3-oxotetradecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28726 CHEBI:28725 biolink:ChemicalSubstance N(6')-acetylkanamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28725 CHEBI:28728 biolink:ChemicalSubstance thromboxane B2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28728 CHEBI:28727 biolink:ChemicalSubstance trans-vaccenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28727 CHEBI:28721 biolink:ChemicalSubstance ribulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28721 CHEBI:28724 biolink:ChemicalSubstance 9,10-dihydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28724 CHEBI:28723 biolink:ChemicalSubstance D-glycero-D-manno-heptose 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28723 CHEBI:7508 biolink:ChemicalSubstance framycetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_7508 CHEBI:7507 biolink:ChemicalSubstance neomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_7507 CHEBI:28729 biolink:ChemicalSubstance alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28729 chebi_ph7_3 NCBITaxon:41944 biolink:OrganismalEntity Myrtales go-plus.json Myrtanae http://purl.obolibrary.org/obo/NCBITaxon_41944 CHEBI:28733 biolink:ChemicalSubstance 1-linoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28733 chebi_ph7_3 CHEBI:28731 biolink:ChemicalSubstance gibberellin A19 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28731 NCBITaxon:41938 biolink:OrganismalEntity Malvales go-plus.json Malvanae http://purl.obolibrary.org/obo/NCBITaxon_41938 CHEBI:7510 biolink:ChemicalSubstance neopinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_7510 CHEBI:28706 biolink:ChemicalSubstance trans-hex-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28706 NCBITaxon:41937 biolink:OrganismalEntity Sapindales go-plus.json Rutanae http://purl.obolibrary.org/obo/NCBITaxon_41937 CHEBI:28700 biolink:ChemicalSubstance 20-hydroxy-leukotriene E4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28700 CHEBI:28701 biolink:ChemicalSubstance chenodeoxycholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28701 GO:0038195 biolink:BiologicalProcess urokinase plasminogen activator signaling pathway A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json uPA signaling pathway http://purl.obolibrary.org/obo/GO_0038195 GO:0038194 biolink:BiologicalProcess thyroid-stimulating hormone signaling pathway The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json TSH signaling pathway|thyrotropin signaling pathway http://purl.obolibrary.org/obo/GO_0038194 GO:0038197 biolink:CellularComponent type I interferon receptor complex A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). go-plus.json interferon-alpha/beta receptor complex http://purl.obolibrary.org/obo/GO_0038197 GO:0038196 biolink:BiologicalProcess type III interferon signaling pathway A series of molecular signals initiated by the binding of a type III interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far. go-plus.json type III interferon-activated signaling pathway|interferon lambda signaling pathway http://purl.obolibrary.org/obo/GO_0038196 GO:0038199 biolink:MolecularActivity ethylene receptor activity Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity. go-plus.json ethylene response sensor|C2H4 receptor activity http://purl.obolibrary.org/obo/GO_0038199 GO:0038198 biolink:MolecularActivity auxin receptor activity Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone). go-plus.json http://purl.obolibrary.org/obo/GO_0038198 CHEBI:28715 biolink:ChemicalSubstance 5-hydroxykynurenamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28715 CHEBI:28717 biolink:ChemicalSubstance O-decanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28717 chebi_ph7_3 CHEBI:28716 biolink:ChemicalSubstance palmitoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28716 GO:0038191 biolink:MolecularActivity neuropilin binding Binding to a member of the neuropilin family. go-plus.json neuropilin-binding|Nrp binding|Nrp ligand http://purl.obolibrary.org/obo/GO_0038191 GO:0038190 biolink:BiologicalProcess VEGF-activated neuropilin signaling pathway A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json VEGF-Npn-1 signaling|vascular endothelial growth factor-activated neuropilin signaling pathway http://purl.obolibrary.org/obo/GO_0038190 CHEBI:28710 biolink:ChemicalSubstance 3-hydroxy-3-methyl-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28710 GO:0038193 biolink:BiologicalProcess thromboxane A2 signaling pathway The series of molecular signals generated as a consequence of thromboxane A2 binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json TXA(2) receptor signaling|TXA2 signaling http://purl.obolibrary.org/obo/GO_0038193 GO:0038192 biolink:BiologicalProcess gastric inhibitory peptide signaling pathway The series of molecular signals generated as a consequence of a gastric inhibitory peptide (GIP) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json GIP signaling|glucose-dependent insulinotropic polypeptide signaling|gastric inhibitory polypeptide receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038192 GO:0038184 biolink:BiologicalProcess cell surface bile acid receptor signaling pathway A series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json membrane bile acid receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038184 GO:0038183 biolink:BiologicalProcess bile acid signaling pathway A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0038183 GO:0038186 biolink:MolecularActivity lithocholic acid receptor activity Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity. go-plus.json LCA receptor activity http://purl.obolibrary.org/obo/GO_0038186 GO:0038185 biolink:BiologicalProcess intracellular bile acid receptor signaling pathway A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json nuclear bile acid receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038185 GO:0038188 biolink:BiologicalProcess cholecystokinin signaling pathway The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription. Wikipedia:Cholecystokinin go-plus.json CCK signaling|cholecystokinin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038188 CHEBI:28719 biolink:ChemicalSubstance 4-hydroxyphenylglyoxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28719 CHEBI:28718 biolink:ChemicalSubstance L-allothreonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28718 GO:0038187 biolink:MolecularActivity pattern recognition receptor activity Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. Wikipedia:Pattern_recognition_receptor go-plus.json PRR activity|pathogen associated molecular pattern receptor activity|MAMP receptor activity|PRR|signaling pattern recognition receptor activity|PAMP receptor activity|macrophage receptor activity|microbe-associated molecular pattern receptor activity http://purl.obolibrary.org/obo/GO_0038187 GO:0038189 biolink:BiologicalProcess neuropilin signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json Npn signaling http://purl.obolibrary.org/obo/GO_0038189 GO:0038180 biolink:BiologicalProcess nerve growth factor signaling pathway A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Wikipedia:Nerve_growth_factor go-plus.json NGF signaling pathway|nerve growth factor signalling pathway http://purl.obolibrary.org/obo/GO_0038180 GO:0038182 biolink:MolecularActivity G protein-coupled bile acid receptor activity Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. Wikipedia:G_protein-coupled_bile_acid_receptor go-plus.json cell surface bile acid receptor|G-protein coupled bile acid receptor activity|membrane bile acid receptor activity http://purl.obolibrary.org/obo/GO_0038182 GO:0038181 biolink:MolecularActivity bile acid receptor activity Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile. go-plus.json http://purl.obolibrary.org/obo/GO_0038181 GO:0038173 biolink:BiologicalProcess interleukin-17A-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-17A to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL17A signaling pathway|IL-17A-mediated signaling pathway|interleukin-17A-mediated signalling pathway|interleukin-17A signaling pathway|IL17a signaling pathway http://purl.obolibrary.org/obo/GO_0038173 GO:0038172 biolink:BiologicalProcess interleukin-33-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-33-mediated signaling pathway|IL33 signaling pathway|interleukin-33-mediated signalling pathway|interleukin-33 signaling pathway http://purl.obolibrary.org/obo/GO_0038172 CHEBI:7540 biolink:ChemicalSubstance neurosporaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_7540 GO:0038175 biolink:BiologicalProcess negative regulation of SREBP signaling pathway in response to increased oxygen levels Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels. go-plus.json negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels|negative regulation of SREBP-mediated signaling pathway in presence of oxygen http://purl.obolibrary.org/obo/GO_0038175 GO:0038174 biolink:MolecularActivity interleukin-17A receptor activity Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0038174 GO:0038177 biolink:MolecularActivity death receptor agonist activity Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor. go-plus.json death receptor activator activity http://purl.obolibrary.org/obo/GO_0038177 GO:0038176 biolink:BiologicalProcess positive regulation of SREBP signaling pathway in response to decreased oxygen levels Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels. go-plus.json positive regulation of SREBP-mediated signaling pathway in absence of oxygen|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels http://purl.obolibrary.org/obo/GO_0038176 GO:0038179 biolink:BiologicalProcess neurotrophin signaling pathway A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. go-plus.json neurotrophin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038179 GO:0038178 biolink:BiologicalProcess complement component C5a signaling pathway A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor. go-plus.json complement component C5a-induced signaling pathway http://purl.obolibrary.org/obo/GO_0038178 CHEBI:77703 biolink:ChemicalSubstance EC 4.3.1.3 (histidine ammonia-lyase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77703 NCBITaxon:1142503 biolink:OrganismalEntity Rhizophydiales incertae sedis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1142503 CHEBI:77706 biolink:ChemicalSubstance EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77706 GO:0038171 biolink:BiologicalProcess cannabinoid signaling pathway The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids. go-plus.json cannabinoid receptor signaling pathway|cannabinoid-mediated signaling pathway|cannabinoid-activated signaling pathway http://purl.obolibrary.org/obo/GO_0038171 GO:0038170 biolink:BiologicalProcess somatostatin signaling pathway The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json somatostatin-activated somatostatin receptor signaling pathway|somatostatin signalling pathway|somatotrophin release inhibiting factor signaling pathway|SRIF signaling pathway|somatostatin-mediated signaling pathway|SST signaling pathway http://purl.obolibrary.org/obo/GO_0038170 CHEBI:77705 biolink:ChemicalSubstance EC 3.4.19.* (omega-peptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77705 CHEBI:77709 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')--N-acylsphingosine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77709 chebi_ph7_3 GO:0038169 biolink:BiologicalProcess somatostatin receptor signaling pathway The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json SST receptor signaling pathway|SSTR signaling pathway http://purl.obolibrary.org/obo/GO_0038169 GO:0038162 biolink:BiologicalProcess erythropoietin-mediated signaling pathway A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json erythropoietin receptor signaling pathway|EPO-R signaling pathway http://purl.obolibrary.org/obo/GO_0038162 GO:0038161 biolink:BiologicalProcess prolactin signaling pathway A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json prolactin-mediated signaling pathway|PRL signaling pathway http://purl.obolibrary.org/obo/GO_0038161 GO:0038164 biolink:MolecularActivity thrombopoietin receptor activity Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0038164 GO:0038163 biolink:BiologicalProcess thrombopoietin-mediated signaling pathway A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json thrombopoietin receptor signaling pathway|THPO signaling pathway|THPO/MPL signaling pathway http://purl.obolibrary.org/obo/GO_0038163 CHEBI:77700 biolink:ChemicalSubstance methyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77700 chebi_ph7_3 GO:0038166 biolink:BiologicalProcess angiotensin-activated signaling pathway The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json angiotensin-mediated signaling pathway|angiotensin receptor signaling pathway|angiotensin II-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038166 GO:0038165 biolink:BiologicalProcess oncostatin-M-mediated signaling pathway A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. go-plus.json oncostatin-M signaling pathway|OSM signaling pathway http://purl.obolibrary.org/obo/GO_0038165 GO:0038168 biolink:BiologicalProcess epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB. go-plus.json EGFR signaling pathway via IKK-dependent activation of NF-kappaB|EGFR signaling pathway via IKK/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0038168 GO:0038167 biolink:BiologicalProcess epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via activation of the transcription factor NF-kappaB. go-plus.json epidermal growth factor receptor signalling pathway via positive regulation of NF-kappaB transcription factor activity|EGFR signaling pathway via activation of NF-kappaB http://purl.obolibrary.org/obo/GO_0038167 CHEBI:77715 biolink:ChemicalSubstance nasal decongestant go-plus.json http://purl.obolibrary.org/obo/CHEBI_77715 CHEBI:77712 biolink:ChemicalSubstance xanthoaphin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77712 chebi_ph7_3 CHEBI:77718 biolink:ChemicalSubstance carboxamidinium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77718 GO:0038160 biolink:BiologicalProcess CXCL12-activated CXCR4 signaling pathway A series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CXCL12-activated CXCR4 signalling pathway http://purl.obolibrary.org/obo/GO_0038160 CHEBI:77717 biolink:ChemicalSubstance 2,2'-lysobisphosphatidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77717 chebi_ph7_3 GO:0038159 biolink:BiologicalProcess C-X-C chemokine receptor CXCR4 signaling pathway A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CXCR4 signaling pathway http://purl.obolibrary.org/obo/GO_0038159 GO:0038158 biolink:BiologicalProcess granulocyte colony-stimulating factor signaling pathway A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R). go-plus.json CSF3 signaling pathway|G-CSF receptor signaling pathway|G-CSF signaling pathway|granulocyte colony-stimulating factor receptor signaling pathway|granulocyte colony-stimulating factor signalling pathway http://purl.obolibrary.org/obo/GO_0038158 CHEBI:7524 biolink:ChemicalSubstance nerolidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_7524 GO:0038151 biolink:BiologicalProcess CCL2-activated CCR2 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL2/CCR2 signaling pathway http://purl.obolibrary.org/obo/GO_0038151 GO:0038150 biolink:BiologicalProcess C-C chemokine receptor CCR2 signaling pathway A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json C-C chemokine receptor type 2 signaling pathway http://purl.obolibrary.org/obo/GO_0038150 GO:0038153 biolink:BiologicalProcess CCL2-activated CCR4 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL2/CCR4 signaling pathway http://purl.obolibrary.org/obo/GO_0038153 GO:0038152 biolink:BiologicalProcess C-C chemokine receptor CCR4 signaling pathway A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json chemokine receptor CCR4 signaling pathway|C-C chemokine receptor type 4 signaling pathway http://purl.obolibrary.org/obo/GO_0038152 GO:0038155 biolink:BiologicalProcess interleukin-23-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-23-mediated signalling pathway|IL-23-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038155 CHEBI:77711 biolink:ChemicalSubstance licodione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77711 chebi_ph7_3 GO:0038154 biolink:BiologicalProcess interleukin-11-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-11-mediated signalling pathway|IL-11-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038154 CHEBI:77710 biolink:ChemicalSubstance 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77710 chebi_ph7_3 GO:0038157 biolink:BiologicalProcess granulocyte-macrophage colony-stimulating factor signaling pathway A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. go-plus.json CSF2 signaling pathway|GM-CSF receptor signaling pathway|granulocyte-macrophage colony-stimulating factor receptor signaling pathway|GM-CSF signaling pathway|granulocyte-macrophage colony-stimulating factor signalling pathway http://purl.obolibrary.org/obo/GO_0038157 GO:0038156 biolink:BiologicalProcess interleukin-3-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-3 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-3-mediated signalling pathway|IL-3-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038156 CHEBI:77726 biolink:ChemicalSubstance 1-decanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77726 chebi_ph7_3 CHEBI:77725 biolink:ChemicalSubstance 17-O-acetylnorajmaline(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77725 chebi_ph7_3 CHEBI:77724 biolink:ChemicalSubstance 1-decanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77724 chebi_ph7_3 CHEBI:77728 biolink:ChemicalSubstance bergaptol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77728 chebi_ph7_3 CHEBI:77727 biolink:ChemicalSubstance delta-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_77727 GO:0038148 biolink:BiologicalProcess chemokine (C-C motif) ligand 2 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL2 signaling pathway http://purl.obolibrary.org/obo/GO_0038148 GO:0038147 biolink:MolecularActivity C-X-C motif chemokine 12 receptor activity Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json CXCR7|CXCR4|stromal cell-derived factor-1 receptor activity|CXCL12 receptor activity|SDF-1 receptor activity http://purl.obolibrary.org/obo/GO_0038147 GO:0038149 biolink:MolecularActivity C-C motif chemokine 2 receptor activity Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json CCL2 receptor activity http://purl.obolibrary.org/obo/GO_0038149 CHEBI:7539 biolink:ChemicalSubstance 5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7539 GO:0038140 biolink:CellularComponent ERBB4-ERBB3 complex A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission. go-plus.json ERBB3-ERBB4 complex|ERBB4:ERBB3 heterodimer http://purl.obolibrary.org/obo/GO_0038140 GO:0038142 biolink:CellularComponent EGFR:ERBB2 complex A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. go-plus.json EGFR:ERBB2 heterodimer|EGF:EGFR:ERBB2 complex http://purl.obolibrary.org/obo/GO_0038142 GO:0038141 biolink:CellularComponent ERBB4-ERBB4 complex A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4). go-plus.json ERBB4 homodimer http://purl.obolibrary.org/obo/GO_0038141 GO:0038144 biolink:CellularComponent ERBB4:ERBB2 complex A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4. go-plus.json NRGs/EGFLs:ERBB4:ERBB2|ERBB4:ERBB2 heterodimer http://purl.obolibrary.org/obo/GO_0038144 CHEBI:77722 biolink:ChemicalSubstance apigenin 7-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77722 chebi_ph7_3 GO:0038143 biolink:CellularComponent ERBB3:ERBB2 complex A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. go-plus.json EGFR:ERBB2 heterodimer|NRG1/2:ERBB3:ERBB2 http://purl.obolibrary.org/obo/GO_0038143 GO:0038146 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 12 signaling pathway A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json SDF1 signaling pathway|stromal cell-derived factor-1 signaling pathway|CXCL12 signaling pathway|CXCL12-activated CXCR7 signaling pathway http://purl.obolibrary.org/obo/GO_0038146 CHEBI:77720 biolink:ChemicalSubstance 1,1'-lysobisphosphatidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77720 chebi_ph7_3 GO:0038145 biolink:BiologicalProcess macrophage colony-stimulating factor signaling pathway A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json M-CSF signaling pathway|macrophage colony-stimulating factor signalling pathway http://purl.obolibrary.org/obo/GO_0038145 GO:0004800 biolink:MolecularActivity thyroxine 5'-deiodinase activity Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2. MetaCyc:THYROXINE-DEIODINASE-RXN|EC:1.21.99.4|Reactome:R-HSA-209772|Reactome:R-HSA-350869|RHEA:19745 go-plus.json type II iodothyronine deiodinase activity|outer ring-deiodinating pathway|type I iodothyronine deiodinase activity|iodothyronine outer ring monodeiodinase activity|thyroxine deiodinase activity|acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)|diiodothyronine 5'-deiodinase activity|iodothyronine 5'-deiodinase activity|L-thyroxine iodohydrolase (reducing) activity|thyroxine 5' deiodinase activity http://purl.obolibrary.org/obo/GO_0004800 GO:0004802 biolink:MolecularActivity transketolase activity Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor. EC:2.2.1.1|Reactome:R-HSA-163741|Reactome:R-HSA-163751|MetaCyc:1TRANSKETO-RXN|Reactome:R-HSA-71324|RHEA:10508|Reactome:R-HSA-71335 go-plus.json glycolaldehydetransferase activity|sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity|glycoaldehyde transferase activity|fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity http://purl.obolibrary.org/obo/GO_0004802 GO:0004801 biolink:MolecularActivity transaldolase activity Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. EC:2.2.1.2|RHEA:17053|Reactome:R-HSA-163764|MetaCyc:TRANSALDOL-RXN|Reactome:R-HSA-5659989|Reactome:R-HSA-71334|Reactome:R-HSA-5659998 go-plus.json dihydroxyacetone transferase activity|glycerone transferase activity|dihydroxyacetonetransferase activity|sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity http://purl.obolibrary.org/obo/GO_0004801 UBERON:0035956 biolink:AnatomicalEntity epididymal lumen The lumen of the epididymis go-plus.json lumen of epididymis|epididymis lumen http://purl.obolibrary.org/obo/UBERON_0035956 CHEBI:14158 biolink:ChemicalSubstance dihydromonacolin L go-plus.json http://purl.obolibrary.org/obo/CHEBI_14158 chebi_ph7_3 GO:0004808 biolink:MolecularActivity tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate. RHEA:19569|MetaCyc:2.1.1.61-RXN|KEGG_REACTION:R00601|EC:2.1.1.61 go-plus.json S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity|tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity|transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity http://purl.obolibrary.org/obo/GO_0004808 GO:0004807 biolink:MolecularActivity triose-phosphate isomerase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate. EC:5.3.1.1|RHEA:18585|MetaCyc:TRIOSEPISOMERIZATION-RXN|Reactome:R-HSA-70454|Reactome:R-HSA-70481|KEGG_REACTION:R01015 go-plus.json phosphotriose isomerase activity|triose phosphate mutase activity|D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity|triosephosphate mutase activity|D-glyceraldehyde-3-phosphate ketol-isomerase activity|triosephosphate isomerase activity|triose phosphoisomerase activity http://purl.obolibrary.org/obo/GO_0004807 CHEBI:38120 biolink:ChemicalSubstance but-3-en-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38120 chebi_ph7_3 GO:0004809 biolink:MolecularActivity tRNA (guanine-N2-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine. Reactome:R-HSA-6782416|Reactome:R-HSA-6786501 go-plus.json tRNA 2,2-dimethylguanosine-26 methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity|tRNA(m(2,2)G26)dimethyltransferase activity|transfer RNA guanine 2-methyltransferase activity|transfer ribonucleate guanine N2-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity|transfer ribonucleate guanine 2-methyltransferase activity|tRNA(guanine-26,N2-N2) methyltransferase activity|tRNA(guanine-26,N(2)-N(2)) methyltransferase activity|guanine-N2-methylase activity|N2,N2-dimethylguanine tRNA methyltransferase activity|N(2),N(2)-dimethylguanine tRNA methyltransferase activity http://purl.obolibrary.org/obo/GO_0004809 GO:0004804 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004804 CHEBI:38124 biolink:ChemicalSubstance dialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_38124 GO:0004803 biolink:MolecularActivity transposase activity Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. go-plus.json P-element encoded transposase activity http://purl.obolibrary.org/obo/GO_0004803 goslim_pir|goslim_metagenomics GO:0004806 biolink:MolecularActivity triglyceride lipase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate. RHEA:12044|Reactome:R-HSA-8848339|Reactome:R-HSA-8848338|EC:3.1.1.3|MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|Reactome:R-HSA-1482777|Reactome:R-HSA-5694109|Reactome:R-HSA-163551 go-plus.json meito MY 30|triacetinase activity|heparin releasable hepatic lipase|butyrinase activity|meito sangyo OF lipase|amano AP|glycerol-ester hydrolase activity|amano B|cacordase activity|triolein hydrolase activity|triglyceride hydrolase activity|triacylglycerol acylhydrolase activity|salt-resistant post-heparin lipase|tween-hydrolyzing esterase activity|TAG activity|lipazin|tributyrinase activity|hepatic monoacylglycerol acyltransferase|tween hydrolase activity|takedo 1969-4-9|PPL|amano CE|glycerol ester hydrolase activity|triacylglycerol ester hydrolase activity|tributyrase activity|GEH|hepatic lipase|triacylglycerol lipase activity|post-heparin plasma protamine-resistant lipase|tweenase activity|GA 56|amano CES|amano P|steapsin|liver lipase|tweenesterase activity|tributyrin esterase activity|capalase L|amno N-AP|triglyceridase activity http://purl.obolibrary.org/obo/GO_0004806 goslim_chembl CHEBI:7587 biolink:ChemicalSubstance nitroalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_7587 GO:0004805 biolink:MolecularActivity trehalose-phosphatase activity Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate. MetaCyc:TREHALOSEPHOSPHA-RXN|EC:3.1.3.12|RHEA:23420 go-plus.json trehalose 6-phosphate phosphatase activity|trehalose 6-phosphatase activity|trehalose-6-phosphate phosphohydrolase activity|trehalose phosphatase activity http://purl.obolibrary.org/obo/GO_0004805 CHEBI:38122 biolink:ChemicalSubstance 2-chloro-4-carboxymethylenebut-2-en-1,4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38122 CHEBI:87091 biolink:ChemicalSubstance 8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_87091 chebi_ph7_3 GO:0004811 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004811 GO:0004810 biolink:MolecularActivity tRNA adenylyltransferase activity Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1). MetaCyc:TRNA-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.72 go-plus.json transfer ribonucleic adenylyl (cytidylyl) transferase|tRNA-nucleotidyltransferase activity|transfer ribonucleate cytidylyltransferase|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|ATP:tRNA adenylyltransferase activity|tRNA CCA-pyrophosphorylase activity|tRNA CCA-diphosphorylase activity|transfer ribonucleate adenylyltransferase|transfer ribonucleate nucleotidyltransferase|CCA-adding enzyme activity|CTP(ATP):tRNA nucleotidyltransferase|transfer RNA adenylyltransferase|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|ATP (CTP):tRNA nucleotidyltransferase|-C-C-A pyrophosphorylase|transfer ribonucleate adenyltransferase activity|ribonucleic cytidylyltransferase|transfer-RNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase|ATP(CTP)-tRNA nucleotidyltransferase|transfer ribonucleic acid nucleotidyl transferase http://purl.obolibrary.org/obo/GO_0004810 CHEBI:87090 biolink:ChemicalSubstance (7R)-6-deoxy-D-manno-oct-7-ulosuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87090 chebi_ph7_3 GO:0004813 biolink:MolecularActivity alanine-tRNA ligase activity Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). Reactome:R-HSA-379864|MetaCyc:ALANINE--TRNA-LIGASE-RXN|EC:6.1.1.7|RHEA:12540|Reactome:R-HSA-380177 go-plus.json alanine tRNA synthetase activity|alanine transfer RNA synthetase activity|Ala-tRNA synthetase activity|alanyl-transfer ribonucleate synthase activity|alanyl-transfer ribonucleic acid synthetase activity|alanyl-transfer ribonucleate synthetase activity|alanine-transfer RNA ligase activity|alanyl-transfer RNA synthetase activity|alanine translase activity|AlaRS|alanyl-tRNA synthetase activity|L-alanine:tRNAAla ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0004813 GO:0004812 biolink:MolecularActivity aminoacyl-tRNA ligase activity Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP. EC:6.1.1.- go-plus.json ligase activity, forming aminoacyl-tRNA and related compounds|aminoacyl-tRNA synthetase auxiliary protein activity|aminoacyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004812 CHEBI:87095 biolink:ChemicalSubstance lipid A 1-(2-aminoethyl diphosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87095 chebi_ph7_3 CHEBI:87097 biolink:ChemicalSubstance lipid A 4'-(2-aminoethyl diphosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87097 chebi_ph7_3 CHEBI:53756 biolink:ChemicalSubstance HIV-1 reverse transcriptase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_53756 CHEBI:87096 biolink:ChemicalSubstance lipid A 1,4'-bis(2-aminoethyl diphosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87096 chebi_ph7_3 UBERON:0011980 biolink:AnatomicalEntity crurotarsal joint A joint that connects the bones of the crus to the proximal tarsal bones go-plus.json crurotarsal http://purl.obolibrary.org/obo/UBERON_0011980 UBERON:0011977 biolink:AnatomicalEntity epiphysis of proximal phalanx of manus An epiphysis that is part of a proximal phalanx of manus. go-plus.json epiphysis of proximal phalanx of finger http://purl.obolibrary.org/obo/UBERON_0011977 UBERON:0011976 biolink:AnatomicalEntity epiphysis of distal phalanx of pes An epiphysis that is part of a distal phalanx of pes. go-plus.json epiphysis of distal phalanx of toe http://purl.obolibrary.org/obo/UBERON_0011976 UBERON:0035965 biolink:AnatomicalEntity wall of blood vessel go-plus.json blood vessel wall|vascular wall http://purl.obolibrary.org/obo/UBERON_0035965 CHEBI:38139 biolink:ChemicalSubstance (1S,2R)-1,2-dihydronaphthalene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38139 chebi_ph7_3 UBERON:0011975 biolink:AnatomicalEntity epiphysis of middle phalanx of pes An epiphysis that is part of a middle phalanx of pes. go-plus.json epiphysis of middle phalanx of toe http://purl.obolibrary.org/obo/UBERON_0011975 UBERON:0011974 biolink:AnatomicalEntity epiphysis of proximal phalanx of pes An epiphysis that is part of a proximal phalanx of pes. go-plus.json epiphysis of proximal phalanx of toe http://purl.obolibrary.org/obo/UBERON_0011974 UBERON:0011979 biolink:AnatomicalEntity epiphysis of distal phalanx of manus An epiphysis that is part of a distal phalanx of manus. go-plus.json epiphysis of distal phalanx of finger http://purl.obolibrary.org/obo/UBERON_0011979 CHEBI:14148 biolink:ChemicalSubstance dihydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_14148 UBERON:0011978 biolink:AnatomicalEntity epiphysis of middle phalanx of manus An epiphysis that is part of a middle phalanx of manus. go-plus.json epiphysis of middle phalanx of finger http://purl.obolibrary.org/obo/UBERON_0011978 GO:0004819 biolink:MolecularActivity glutamine-tRNA ligase activity Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). EC:6.1.1.18|RHEA:20121|MetaCyc:GLUTAMINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379982|Reactome:R-HSA-380241 go-plus.json glutaminyl-transfer RNA synthetase activity|L-glutamine:tRNAGln ligase (AMP-forming)|glutaminyl-transfer ribonucleate synthetase activity|glutamine-tRNA synthetase activity|glutamine translase activity|glutaminyl ribonucleic acid|GlnRS|glutaminyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004819 CHEBI:38132 biolink:ChemicalSubstance indanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_38132 GO:0004818 biolink:MolecularActivity glutamate-tRNA ligase activity Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). EC:6.1.1.17|Reactome:R-HSA-379861|RHEA:23540|Reactome:R-HSA-380216|MetaCyc:GLURS-RXN go-plus.json glutamyl-transfer ribonucleate synthetase activity|L-glutamate:tRNAGlu ligase (AMP-forming) activity|glutamic acid translase activity|glutamyl-tRNA synthetase activity|glutamyl-transfer ribonucleic acid synthetase activity|glutamate-tRNA synthetase activity|glutamyl-transfer RNA synthetase activity http://purl.obolibrary.org/obo/GO_0004818 CHEBI:38131 biolink:ChemicalSubstance lactol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38131 CHEBI:53753 biolink:ChemicalSubstance triolein go-plus.json http://purl.obolibrary.org/obo/CHEBI_53753 chebi_ph7_3 GO:0004815 biolink:MolecularActivity aspartate-tRNA ligase activity Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). Reactome:R-HSA-379867|EC:6.1.1.12|RHEA:19649|MetaCyc:ASPARTATE--TRNA-LIGASE-RXN|Reactome:R-HSA-380229 go-plus.json aspartyl ribonucleate synthetase activity|aspartyl-tRNA synthetase activity|aspartyl-transfer RNA synthetase activity|aspartyl ribonucleic synthetase activity|L-aspartate:tRNAAsp ligase (AMP-forming)|aspartic acid translase activity|aspartyl-transfer ribonucleic acid synthetase activity http://purl.obolibrary.org/obo/GO_0004815 GO:0004814 biolink:MolecularActivity arginine-tRNA ligase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). RHEA:20301|Reactome:R-HSA-379993|MetaCyc:ARGININE--TRNA-LIGASE-RXN|Reactome:R-HSA-380224|EC:6.1.1.19 go-plus.json arginyl-transfer ribonucleate synthetase activity|arginyl transfer ribonucleic acid synthetase activity|arginine translase activity|arginyl-transfer RNA synthetase activity|L-arginine:tRNAArg ligase (AMP-forming)|arginyl-tRNA synthetase activity|arginine-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004814 GO:0004817 biolink:MolecularActivity cysteine-tRNA ligase activity Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys). Reactome:R-HSA-379887|EC:6.1.1.16|RHEA:17773|MetaCyc:CYSTEINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380158 go-plus.json cysteinyl-transferRNA synthetase activity|cysteinyl-transfer ribonucleate synthetase activity|cysteine translase activity|cysteinyl-tRNA synthetase activity|L-cysteine:tRNACys ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0004817 GO:0004816 biolink:MolecularActivity asparagine-tRNA ligase activity Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+). KEGG_REACTION:R03648|EC:6.1.1.22|Reactome:R-HSA-379996|MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN|RHEA:11180|Reactome:R-HSA-380227 go-plus.json asparagine translase activity|asparaginyl transfer RNA synthetase activity|L-asparagine:tRNAAsn ligase (AMP-forming)|asparaginyl-transfer ribonucleate synthetase activity|asparagyl-transfer RNA synthetase activity|asparaginyl transfer ribonucleic acid synthetase activity|asparaginyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004816 CHEBI:38133 biolink:ChemicalSubstance naphthalenediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_38133 CHEBI:7570 biolink:ChemicalSubstance nigerose go-plus.json http://purl.obolibrary.org/obo/CHEBI_7570 chebi_ph7_3 CHEBI:28788 biolink:ChemicalSubstance quinoline-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28788 chebi_ph7_3 CHEBI:28787 biolink:ChemicalSubstance nitroglycerin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28787 chebi_ph7_3 CHEBI:53746 biolink:ChemicalSubstance EC 1.1.1.205 (IMP dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_53746 CHEBI:28789 biolink:ChemicalSubstance L-glucitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28789 chebi_ph7_3 CHEBI:28785 biolink:ChemicalSubstance (+)-ureidoglycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28785 UBERON:0011973 biolink:AnatomicalEntity epiphysis of phalanx of pes An epiphysis that is part of a phalanx of a pes [Automatically generated definition]. go-plus.json epiphysis of phalanx of toe http://purl.obolibrary.org/obo/UBERON_0011973 UBERON:0011972 biolink:AnatomicalEntity medial ligament of ankle joint A skeletal ligament that connects a tibia and connects a tarsal skeleton. go-plus.json ligamentum collaterale mediale articulationis talocruralis|deltoid collateral ligament of ankle joint|medial collateral ligament of ankle joint|ligamentum deltoideum|ligamentum deltoideum (articulatio talocruralis)|ligamentum collaterale mediale (articulatio talocruralis)|deltoid ligament of ankle joint http://purl.obolibrary.org/obo/UBERON_0011972 CHEBI:38107 biolink:ChemicalSubstance trans-4-carboxymethylenebut-2-en-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38107 UBERON:0011965 biolink:AnatomicalEntity saddle joint In a saddle joint (sellar joint, articulation by reciprocal reception) the opposing surfaces are reciprocally concave-convex. go-plus.json articulation by reciprocal reception|sellar joint http://purl.obolibrary.org/obo/UBERON_0011965 CHEBI:38106 biolink:ChemicalSubstance organosulfur heterocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38106 CHEBI:38104 biolink:ChemicalSubstance oxacycle go-plus.json http://purl.obolibrary.org/obo/CHEBI_38104 CHEBI:38109 biolink:ChemicalSubstance (R)-azetidine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38109 CHEBI:38108 biolink:ChemicalSubstance azetidine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38108 CHEBI:14178 biolink:ChemicalSubstance 1D-myo-inositol bis(diphosphate) tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_14178 CHEBI:38102 biolink:ChemicalSubstance triazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38102 CHEBI:38101 biolink:ChemicalSubstance organonitrogen heterocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38101 CHEBI:28794 biolink:ChemicalSubstance coumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28794 chebi_ph7_3 CHEBI:28797 biolink:ChemicalSubstance D-alpha-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28797 CHEBI:28796 biolink:ChemicalSubstance fructan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28796 CHEBI:28791 biolink:ChemicalSubstance isoglutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28791 CHEBI:28790 biolink:ChemicalSubstance serotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28790 UBERON:0011960 biolink:AnatomicalEntity articular capsule of glenohumeral joint An articular capsule that is part of the glenohumeral joint. go-plus.json fibrous capsule of glenohumeral joint|articular capsule of humerus|glenohumeral joint capsule|articular capsule of shoulder joint|capsule of shoulder joint http://purl.obolibrary.org/obo/UBERON_0011960 CHEBI:28793 biolink:ChemicalSubstance beta-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28793 CHEBI:28792 biolink:ChemicalSubstance erucic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28792 CHEBI:38118 biolink:ChemicalSubstance but-2-en-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38118 chebi_ph7_3 UBERON:0011955 biolink:AnatomicalEntity left hepatic vein A hepatic vein that is part of a left lobe of liver. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011955 UBERON:0011953 biolink:AnatomicalEntity stomach glandular region A region of the stomach that is lined with glandular epithelium. go-plus.json glandular stomach http://purl.obolibrary.org/obo/UBERON_0011953 UBERON:0011956 biolink:AnatomicalEntity right hepatic vein A hepatic vein that is part of a right lobe of liver. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011956 CHEBI:38113 biolink:ChemicalSubstance (R,R,R)-nicotianamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38113 NCBITaxon:90964 biolink:OrganismalEntity Staphylococcaceae go-plus.json Staphylococcus group http://purl.obolibrary.org/obo/NCBITaxon_90964 CHEBI:38111 biolink:ChemicalSubstance benzoindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38111 CHEBI:28766 biolink:ChemicalSubstance uroporphyrinogen I go-plus.json http://purl.obolibrary.org/obo/CHEBI_28766 CHEBI:28765 biolink:ChemicalSubstance phosphatidylinositol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28765 CHEBI:28768 biolink:ChemicalSubstance p-cymene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28768 chebi_ph7_3 CHEBI:28767 biolink:ChemicalSubstance 2-deoxy-D-ribose 1,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28767 CHEBI:28761 biolink:ChemicalSubstance N-acetyl-D-galactosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28761 chebi_ph7_3 CHEBI:28763 biolink:ChemicalSubstance 4,4'-dichlorodiphenylmethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28763 chebi_ph7_3 CHEBI:28777 biolink:ChemicalSubstance liquiritigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28777 chebi_ph7_3 CHEBI:28775 biolink:ChemicalSubstance hesperidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28775 chebi_ph7_3 CHEBI:28774 biolink:ChemicalSubstance 3,3',5'-triiodothyronine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28774 CHEBI:28770 biolink:ChemicalSubstance norlaudanosoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28770 CHEBI:14105 biolink:ChemicalSubstance deamido-NAD zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_14105 UBERON:0035927 biolink:AnatomicalEntity sulcus of parietal lobe go-plus.json parietal lobe sulci|parietal lobe sulcus|PLs http://purl.obolibrary.org/obo/UBERON_0035927 CHEBI:28748 biolink:ChemicalSubstance doxorubicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28748 CHEBI:28747 biolink:ChemicalSubstance picolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28747 CHEBI:28749 biolink:ChemicalSubstance aryl beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28749 CHEBI:28744 biolink:ChemicalSubstance 2-hydroxy-17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28744 chebi_ph7_3 CHEBI:28743 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28743 chebi_ph7_3 CHEBI:28745 biolink:ChemicalSubstance L-xylo-hex-3-ulonolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28745 chebi_ph7_3 CHEBI:28759 biolink:ChemicalSubstance 3-oxo-3-phenylpropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28759 CHEBI:28755 biolink:ChemicalSubstance 2,4,6-trichlorophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28755 CHEBI:28757 biolink:ChemicalSubstance fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28757 CHEBI:28751 biolink:ChemicalSubstance biochanin A 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28751 CHEBI:28750 biolink:ChemicalSubstance 17alpha-hydroxypregnenolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28750 chebi_ph7_3 UBERON:0011997 biolink:AnatomicalEntity coelom The aggregate of the coelemic cavity lumen plus the membranes that line the lumen. go-plus.json schizocoelom|coelem|enterocoelom|coelomic cavity|haemocoelom http://purl.obolibrary.org/obo/UBERON_0011997 NCBITaxon:51351 biolink:OrganismalEntity Brassica rapa subsp. pekinensis go-plus.json Brassica rapa var. pekinensis|bai cai|Brassica rapa var. glabra|Brassica rapa Chinese Cabbage Group|Brassica campestris var. pekinensis|Chinese cabbage|Brassica campestris subsp. pekinensis|Brassica campestris (Pekinensis Group)|celery cabbage|pe-tsai|Brassica pekinensis http://purl.obolibrary.org/obo/NCBITaxon_51351 GO:0004767 biolink:MolecularActivity sphingomyelin phosphodiesterase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+). RHEA:19253|Reactome:R-HSA-1640164|Reactome:R-HSA-193706|Reactome:R-HSA-1605797|EC:3.1.4.12|Reactome:R-HSA-1606288|MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-1606273|KEGG_REACTION:R02541 go-plus.json sphingomyelin cholinephosphohydrolase activity|sphingomyelinase activity http://purl.obolibrary.org/obo/GO_0004767 goslim_chembl CHEBI:38091 biolink:ChemicalSubstance spirostanyl glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_38091 GO:0004766 biolink:MolecularActivity spermidine synthase activity Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine. EC:2.5.1.16|MetaCyc:SPERMIDINESYN-RXN|RHEA:12721|Reactome:R-HSA-351215 go-plus.json spermidine synthetase activity|putrescine aminopropyltransferase activity|SpeE|aminopropyltransferase activity|S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity http://purl.obolibrary.org/obo/GO_0004766 CHEBI:38090 biolink:ChemicalSubstance 15beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38090 GO:0004769 biolink:MolecularActivity steroid delta-isomerase activity Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid. EC:5.3.3.1|Reactome:R-HSA-193052|MetaCyc:STEROID-DELTA-ISOMERASE-RXN|Reactome:R-HSA-195690|Reactome:R-HSA-193961|RHEA:14709|Reactome:R-HSA-193073|Reactome:R-HSA-6807052 go-plus.json 3-oxosteroid delta5-delta4-isomerase activity|3-oxosteroid isomerase activity|delta(5)-steroid isomerase activity|delta(5)-3-keto steroid isomerase activity|delta5-ketosteroid isomerase activity|delta(5)-3-oxosteroid isomerase activity|steroid D-isomerase activity|delta5-3-keto steroid isomerase activity|steroid isomerase activity|delta5-3-ketosteroid isomerase activity|delta5(or delta4)-3-keto steroid isomerase activity|delta5-3-oxosteroid isomerase activity|delta(5)-3-ketosteroid isomerase activity|hydroxysteroid isomerase activity|delta5-steroid isomerase activity http://purl.obolibrary.org/obo/GO_0004769 GO:0004768 biolink:MolecularActivity stearoyl-CoA 9-desaturase activity Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O. RHEA:19721|MetaCyc:1.14.19.1-RXN|EC:1.14.19.1|Reactome:R-HSA-8847579|Reactome:R-HSA-5690565 go-plus.json stearoyl-CoA desaturase activity|delta9-desaturase|acyl-CoA desaturase|fatty acid desaturase|delta(9)-desaturase activity http://purl.obolibrary.org/obo/GO_0004768 GO:0004763 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004763 GO:0004762 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004762 GO:0004765 biolink:MolecularActivity shikimate kinase activity Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+). EC:2.7.1.71|MetaCyc:SHIKIMATE-KINASE-RXN|RHEA:13121|KEGG_REACTION:R02412 go-plus.json shikimate kinase (phosphorylating)|shikimate kinase II|ATP:shikimate 3-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004765 CHEBI:38093 biolink:ChemicalSubstance phenothiazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38093 GO:0004764 biolink:MolecularActivity shikimate 3-dehydrogenase (NADP+) activity Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+. EC:1.1.1.282|EC:1.1.1.25|KEGG_REACTION:R06847|MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN|RHEA:17737 go-plus.json shikimate oxidoreductase activity|shikimate:NADP(+) 5-oxidoreductase activity|dehydroshikimic reductase activity|5-dehydroshikimic reductase activity|DHS reductase activity|shikimate:NADP(+) oxidoreductase activity|5-dehydroshikimate reductase activity http://purl.obolibrary.org/obo/GO_0004764 GO:0004761 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004761 CHEBI:87024 biolink:ChemicalSubstance 1-[(6Z,9Z,12Z,15Z)-octadec-6,9,12,15-tetraenoyl]-2-acylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87024 chebi_ph7_3 GO:0004760 biolink:MolecularActivity serine-pyruvate transaminase activity Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine. MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN|RHEA:22852|KEGG_REACTION:R00585|EC:2.6.1.51 go-plus.json hydroxypyruvate:L-alanine transaminase activity|SPT|serine-pyruvate aminotransferase activity|serine-pyruvate aminotransferase, type 1|serine-pyruvate aminotransferase, type 2B|serine-pyruvate aminotransferase, type 2A|serine--pyruvate aminotransferase activity|L-serine:pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0004760 CHEBI:87023 biolink:ChemicalSubstance 1-alpha-linolenoyl 2-acylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87023 chebi_ph7_3 CHEBI:63056 biolink:ChemicalSubstance zinc cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_63056 CHEBI:77696 biolink:ChemicalSubstance 2-hexadecyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77696 chebi_ph7_3 CHEBI:77695 biolink:ChemicalSubstance 1-arachidonyl-2-palmityl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77695 chebi_ph7_3 CHEBI:77694 biolink:ChemicalSubstance 1-arachidonoyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77694 chebi_ph7_3 CHEBI:77699 biolink:ChemicalSubstance methyl formate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77699 chebi_ph7_3 CHEBI:38089 biolink:ChemicalSubstance 15-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38089 GO:0004778 biolink:MolecularActivity succinyl-CoA hydrolase activity Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate. KEGG_REACTION:R00407|RHEA:11516|EC:3.1.2.3|MetaCyc:SUCCINYL-COA-HYDROLASE-RXN go-plus.json succinyl coenzyme A hydrolase activity|succinyl coenzyme A deacylase activity|succinyl-CoA acylase activity http://purl.obolibrary.org/obo/GO_0004778 GO:0004777 biolink:MolecularActivity succinate-semialdehyde dehydrogenase (NAD+) activity Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+. EC:1.2.1.24|RHEA:13217|MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|Reactome:R-HSA-888548 go-plus.json succinate-semialdehyde dehydrogenase activity|succinate semialdehyde dehydrogenase activity|succinate semialdehyde:NAD+ oxidoreductase activity|succinic semialdehyde dehydrogenase activity|succinyl semialdehyde dehydrogenase activity|succinate-semialdehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004777 GO:0004779 biolink:MolecularActivity sulfate adenylyltransferase activity Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate. go-plus.json sulphate adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0004779 GO:0004774 biolink:MolecularActivity succinate-CoA ligase activity Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA. go-plus.json http://purl.obolibrary.org/obo/GO_0004774 CHEBI:63062 biolink:ChemicalSubstance aluminium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_63062 GO:0004773 biolink:MolecularActivity steryl-sulfatase activity Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate. Reactome:R-HSA-1606839|EC:3.1.6.2|MetaCyc:STERYL-SULFATASE-RXN|RHEA:19873 go-plus.json arylsulfatase C activity|steroid 3-sulfatase activity|3-beta-hydroxysteroid sulfate sulfatase activity|dehydroepiandrosterone sulfate sulfatase activity|sterol sulfatase activity|steryl-sulphatase activity|steroid sulfate sulfohydrolase activity|dehydroepiandrosterone sulfatase activity|phenolic steroid sulfatase activity|pregnenolone sulfatase activity|steryl-sulfate sulfohydrolase activity|steroid sulfatase activity http://purl.obolibrary.org/obo/GO_0004773 CHEBI:63061 biolink:ChemicalSubstance UDP-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_63061 GO:0004776 biolink:MolecularActivity succinate-CoA ligase (GDP-forming) activity Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate. KEGG_REACTION:R00432|MetaCyc:SUCCINATE--COA-LIGASE-GDP-FORMING-RXN|EC:6.2.1.4|RHEA:22120|Reactome:R-HSA-71775 go-plus.json succinyl coenzyme A synthetase|succinyl coenzyme A synthetase (GDP-forming) activity|G-STK|SCS|succinate:CoA ligase (GDP-forming) activity|P-enzyme|succinate-phosphorylating enzyme|succinyl-CoA synthetase (GDP-forming) activity|succinic thiokinase|succinyl CoA synthetase activity|succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity http://purl.obolibrary.org/obo/GO_0004776 GO:0004775 biolink:MolecularActivity succinate-CoA ligase (ADP-forming) activity Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate. KEGG_REACTION:R00405|Reactome:R-HSA-70997|EC:6.2.1.5|RHEA:17661|MetaCyc:SUCCCOASYN-RXN go-plus.json succinyl coenzyme A synthetase|succinyl-CoA synthetase activity|A-STK (adenin nucleotide-linked succinate thiokinase)|succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity|succinate thiokinase activity|succinate:CoA ligase (ADP-forming) activity|A-SCS|succinyl-CoA synthetase (ADP-forming) activity|succinic thiokinase http://purl.obolibrary.org/obo/GO_0004775 GO:0004770 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004770 CHEBI:87010 biolink:ChemicalSubstance 1-linoleoyl-2-acylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87010 chebi_ph7_3 CHEBI:63065 biolink:ChemicalSubstance 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene go-plus.json http://purl.obolibrary.org/obo/CHEBI_63065 chebi_ph7_3 GO:0004772 biolink:MolecularActivity sterol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester. go-plus.json sterol-ester synthetase activity|sterol-ester synthase activity http://purl.obolibrary.org/obo/GO_0004772 GO:0004771 biolink:MolecularActivity sterol esterase activity Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid. MetaCyc:STEROL-ESTERASE-RXN|RHEA:10100|Reactome:R-HSA-8865667|Reactome:R-HSA-6813720|Reactome:R-HSA-192417|EC:3.1.1.13 go-plus.json sterol ester hydrolase activity|cholesterol ester hydrolase activity|cholesteryl esterase activity|cholesteryl ester synthase activity|triterpenol esterase activity|cholesterase activity|acylcholesterol lipase activity|cholesterol esterase activity|steryl-ester acylhydrolase activity|cholesterol ester synthase activity|cholesteryl ester hydrolase activity http://purl.obolibrary.org/obo/GO_0004771 goslim_chembl CHEBI:63063 biolink:ChemicalSubstance cadmium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_63063 CHEBI:63069 biolink:ChemicalSubstance neurosporaxanthin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63069 chebi_ph7_3 CHEBI:87017 biolink:ChemicalSubstance 1-gamma-linolenoyl 2-acylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87017 chebi_ph7_3 CHEBI:63068 biolink:ChemicalSubstance octacarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_63068 CHEBI:63067 biolink:ChemicalSubstance zeaxanthin bis(beta-D-glucoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63067 chebi_ph7_3 CHEBI:133221 biolink:ChemicalSubstance 2-oxindole-3-acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133221 CHEBI:631 biolink:ChemicalSubstance 1-hydroxy-2-aminoethylphosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_631 CHEBI:133220 biolink:ChemicalSubstance tuberonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133220 GO:0004745 biolink:MolecularActivity NAD-retinol dehydrogenase activity Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+. Reactome:R-HSA-2466832|RHEA:21284|EC:1.1.1.105|Reactome:R-HSA-2454081|Reactome:R-HSA-5362564|Reactome:R-HSA-5362721|Reactome:R-HSA-5362518|MetaCyc:RETINOL-DEHYDROGENASE-RXN go-plus.json all-trans retinol dehydrogenase activity|retinol (vitamin A1) dehydrogenase activity|retinene reductase activity|retinol dehydrogenase activity|retinal reductase activity http://purl.obolibrary.org/obo/GO_0004745 GO:0004744 biolink:MolecularActivity retinal isomerase activity Catalysis of the reaction: all-trans-retinal = 11-cis-retinal. RHEA:24124|KEGG_REACTION:R02126|MetaCyc:RETINAL-ISOMERASE-RXN go-plus.json all-trans-retinal 11-cis-trans-isomerase activity|retinene isomerase activity|retinoid isomerase activity http://purl.obolibrary.org/obo/GO_0004744 GO:0004747 biolink:MolecularActivity ribokinase activity Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate. RHEA:13697|Reactome:R-HSA-8955844|MetaCyc:RIBOKIN-RXN|EC:2.7.1.15 go-plus.json ATP:D-ribose 5-phosphotransferase activity|D-ribokinase activity|deoxyribokinase activity|ribokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0004747 GO:0004746 biolink:MolecularActivity riboflavin synthase activity Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin. KEGG_REACTION:R00066|MetaCyc:RIBOFLAVIN-SYN-RXN|RHEA:20772|EC:2.5.1.9 go-plus.json riboflavine synthetase activity|heavy riboflavin synthase|lumazine synthase activity|riboflavine synthase activity|vitamin B2 synthase activity|light riboflavin synthase|6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity|riboflavin synthetase activity http://purl.obolibrary.org/obo/GO_0004746 GO:0004741 biolink:MolecularActivity [pyruvate dehydrogenase (lipoamide)] phosphatase activity Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate. Reactome:R-HSA-204169|MetaCyc:3.1.3.43-RXN|RHEA:12669|EC:3.1.3.43 go-plus.json pyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphatase activity|[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity|pyruvate dehydrogenase (lipoamide) phosphatase activity|phosphopyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004741 GO:0004740 biolink:MolecularActivity pyruvate dehydrogenase (acetyl-transferring) kinase activity Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate. MetaCyc:2.7.11.2-RXN|EC:2.7.11.2|RHEA:23052|Reactome:R-HSA-203946 go-plus.json pyruvate dehydrogenase kinase activity|PDH kinase activity|pyruvate dehydrogenase kinase (phosphorylating) activity|PDK|PDHK http://purl.obolibrary.org/obo/GO_0004740 CHEBI:63072 biolink:ChemicalSubstance L-homocysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63072 GO:0004743 biolink:MolecularActivity pyruvate kinase activity Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate. EC:2.7.1.40|RHEA:18159|MetaCyc:PEPDEPHOS-RXN|Reactome:R-HSA-71670|Reactome:R-HSA-71670 go-plus.json phosphoenolpyruvate kinase activity|phosphoenol transphosphorylase activity|ATP:pyruvate 2-O-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004743 CHEBI:38071 biolink:ChemicalSubstance 1,3,5-triazine-2,4-diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38071 chebi_ph7_3 GO:0004742 biolink:MolecularActivity dihydrolipoyllysine-residue acetyltransferase activity Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide. EC:2.3.1.12 go-plus.json dihydrolipoic transacetylase activity|enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity|acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity|lipoic acid acetyltransferase activity|acetyl-CoA:dihydrolipoamide S-acetyltransferase activity|dihydrolipoate acetyltransferase activity|thioltransacetylase A activity|lipoic transacetylase activity|acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity|lipoate transacetylase activity|transacetylase X activity|lipoylacetyltransferase activity|lipoic acetyltransferase activity|lipoate acetyltransferase activity|dihydrolipoamide S-acetyltransferase activity|dihydrolipoyl acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004742 CHEBI:38070 biolink:ChemicalSubstance anti-arrhythmia drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_38070 CHEBI:63070 biolink:ChemicalSubstance beta-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_63070 CHEBI:87044 biolink:ChemicalSubstance 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87044 chebi_ph7_3 CHEBI:87046 biolink:ChemicalSubstance 4alpha-formyl-4beta-methyl-5alpha-8-cholesten-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87046 chebi_ph7_3 CHEBI:87045 biolink:ChemicalSubstance 4alpha-hydroxymethyl-4beta-methyl-5alpha-8-cholesten-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87045 chebi_ph7_3 CHEBI:87048 biolink:ChemicalSubstance palmitoyllipid A(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87048 chebi_ph7_3 CHEBI:87047 biolink:ChemicalSubstance 3beta-hydroxy-4beta-methyl-5alpha-cholest-8-ene-4alpha-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87047 chebi_ph7_3 CHEBI:87049 biolink:ChemicalSubstance lipid IVB(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87049 chebi_ph7_3 CHEBI:38063 biolink:ChemicalSubstance quinolizines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38063 GO:0004749 biolink:MolecularActivity ribose phosphate diphosphokinase activity Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+). EC:2.7.6.1|MetaCyc:PWY0-662|Reactome:R-HSA-111215|RHEA:15609|Reactome:R-HSA-73580|MetaCyc:PRPPSYN-RXN|KEGG_REACTION:R01049 go-plus.json PRPP synthetase activity|phosphoribosylpyrophosphate synthase activity|ribose-5-phosphate pyrophosphokinase activity|phosphoribosyl diphosphate synthetase activity|5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity|phosphoribosyl pyrophosphate synthetase activity|ribophosphate pyrophosphokinase activity|phosphoribosyl-diphosphate synthetase activity|PP-ribose P synthetase activity|phosphoribosylpyrophosphate synthetase activity|pyrophosphoribosylphosphate synthetase activity|5-phosphoribosyl-1-pyrophosphate synthetase activity|5-phosphoribose pyrophosphorylase activity|ATP:D-ribose-5-phosphate diphosphotransferase activity|ribose-phosphate diphosphokinase activity|ribose-phosphate pyrophosphokinase activity|PPRibP synthetase activity http://purl.obolibrary.org/obo/GO_0004749 GO:0004748 biolink:MolecularActivity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. Reactome:R-HSA-111804|EC:1.17.4.1|MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN|RHEA:23252|Reactome:R-HSA-111751 go-plus.json 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004748 CHEBI:38068 biolink:ChemicalSubstance antimalarial go-plus.json http://purl.obolibrary.org/obo/CHEBI_38068 GO:0004756 biolink:MolecularActivity selenide, water dikinase activity Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate. UM-BBD_reactionID:r0833|MetaCyc:2.7.9.3-RXN|EC:2.7.9.3|RHEA:18737|KEGG_REACTION:R03595|Reactome:R-HSA-8959510 go-plus.json selenide,water dikinase activity|selenophosphate synthetase activity|selenophosphate synthase activity|selenium donor protein activity|ATP:selenide, water phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004756 GO:0004755 biolink:MolecularActivity saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH. KEGG_REACTION:R02315|EC:1.5.1.10|RHEA:10020|MetaCyc:RXN3O-127 go-plus.json aminoadipate semialdehyde-glutamate reductase activity|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)|aminoadipic semialdehyde-glutamate reductase activity|N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|aminoadipic semialdehyde-glutamic reductase activity|saccharopine reductase activity|saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004755 GO:0004758 biolink:MolecularActivity serine C-palmitoyltransferase activity Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA. EC:2.3.1.50|RHEA:14761|KEGG_REACTION:R01281|MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN|Reactome:R-HSA-428127 go-plus.json SPT|3-oxosphinganine synthetase activity|serine palmitoyltransferase|palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|acyl-CoA:serine C-2 acyltransferase decarboxylating http://purl.obolibrary.org/obo/GO_0004758 GO:0004757 biolink:MolecularActivity sepiapterin reductase activity Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+. Reactome:R-HSA-1475414|RHEA:18953|MetaCyc:SEPIAPTERIN-REDUCTASE-RXN|Reactome:R-HSA-1497869|EC:1.1.1.153 go-plus.json 7,8-dihydrobiopterin:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004757 CHEBI:38084 biolink:ChemicalSubstance sulfoximide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38084 GO:0004752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004752 GO:0004751 biolink:MolecularActivity ribose-5-phosphate isomerase activity Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate. Reactome:R-HSA-5660015|RHEA:14657|KEGG_REACTION:R01056|EC:5.3.1.6|Reactome:R-HSA-177784|Reactome:R-HSA-5660013|Reactome:R-HSA-71306|MetaCyc:RIB5PISOM-RXN go-plus.json phosphoriboisomerase activity|D-ribose-5-phosphate ketol-isomerase activity|D-ribose 5-phosphate isomerase activity|phosphopentosisomerase activity|ribose phosphate isomerase activity|phosphopentoseisomerase activity|ribose 5-phosphate epimerase activity|D-ribose-5-phosphate aldose-ketose-isomerase activity|5-phosphoribose isomerase activity http://purl.obolibrary.org/obo/GO_0004751 GO:0004754 biolink:MolecularActivity saccharopine dehydrogenase (NAD+, L-lysine-forming) activity Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH. KEGG_REACTION:R00715|MetaCyc:1.5.1.7-RXN|EC:1.5.1.7|RHEA:12440 go-plus.json 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)|epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming) http://purl.obolibrary.org/obo/GO_0004754 GO:0004753 biolink:MolecularActivity saccharopine dehydrogenase activity Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor. go-plus.json lysine-ketoglutarate reductase activity|lysine-2-oxoglutarate reductase activity http://purl.obolibrary.org/obo/GO_0004753 CHEBI:87033 biolink:ChemicalSubstance N-acyl-(4E,8E)-9-methylsphinga-4,8-dienine go-plus.json http://purl.obolibrary.org/obo/CHEBI_87033 chebi_ph7_3 GO:0004750 biolink:MolecularActivity ribulose-phosphate 3-epimerase activity Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate. KEGG_REACTION:R01529|Reactome:R-HSA-199803|RHEA:13677|EC:5.1.3.1|Reactome:R-HSA-71303|MetaCyc:RIBULP3EPIM-RXN go-plus.json ribulose 5-phosphate 3-epimerase activity|D-ribulose 5-phosphate epimerase activity|erythrose-4-phosphate isomerase activity|phosphoketopentose epimerase activity|D-ribulose-5-P 3-epimerase activity|phosphoribulose epimerase activity|phosphoketopentose 3-epimerase activity|D-ribulose phosphate-3-epimerase activity|D-ribulose-5-phosphate epimerase activity|xylulose phosphate 3-epimerase activity|pentose-5-phosphate 3-epimerase activity|erythrose-4-phosphate epimerase activity|D-ribulose-5-phosphate 3-epimerase activity|D-xylulose-5-phosphate 3-epimerase activity http://purl.obolibrary.org/obo/GO_0004750 CHEBI:87034 biolink:ChemicalSubstance aromatic fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87034 CHEBI:87036 biolink:ChemicalSubstance benzimidazole fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87036 CHEBI:38077 biolink:ChemicalSubstance polypyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_38077 CHEBI:38074 biolink:ChemicalSubstance 2-chloro-1,3,5-triazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_38074 chebi_ph7_3 GO:0004759 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004759 GO:0004723 biolink:MolecularActivity calcium-dependent protein serine/threonine phosphatase activity Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions. Reactome:R-HSA-2025882 go-plus.json calcineurin|calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity http://purl.obolibrary.org/obo/GO_0004723 GO:0004722 biolink:MolecularActivity protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. Reactome:R-HSA-199425|Reactome:R-HSA-8948139|Reactome:R-HSA-3002811|Reactome:R-HSA-429730|Reactome:R-HSA-380949|Reactome:R-HSA-9686524|Reactome:R-HSA-6792863|Reactome:R-HSA-3601585|Reactome:R-HSA-6811504|Reactome:R-HSA-5693153|Reactome:R-HSA-9660538|Reactome:R-HSA-163568|Reactome:R-HSA-9619449|Reactome:R-HSA-2187401|Reactome:R-HSA-201790|Reactome:R-HSA-2995388|Reactome:R-HSA-5687758|Reactome:R-HSA-5675431|Reactome:R-HSA-199959|Reactome:R-HSA-5672957|Reactome:R-HSA-4088141|Reactome:R-HSA-5675433|Reactome:R-HSA-9619467|Reactome:R-HSA-9660536|Reactome:R-HSA-209055|Reactome:R-HSA-5694421|Reactome:R-HSA-1295632|Reactome:R-HSA-4419948|Reactome:R-HSA-9658445|EC:3.1.3.16|Reactome:R-HSA-201787|Reactome:R-HSA-5679206|Reactome:R-HSA-5672961|Reactome:R-HSA-5692754|Reactome:R-HSA-9619430|Reactome:R-HSA-1638821|Reactome:R-HSA-5683405|Reactome:R-HSA-74948 go-plus.json protein phosphatase type 4, intrinsic catalyst activity|3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase|protein phosphatase X|phosphospectrin phosphatase|protein phosphatase type 2A, intrinsic catalyst activity|protein phosphatase type 2B, intrinsic catalyst activity|phosphatase 2B|phosphatase 2A|casein phosphatase|phosphatase IV|phosphopyruvate dehydrogenase phosphatase|phosphatase C-II|Aspergillus awamori acid protein phosphatase|magnesium-dependent protein serine/threonine phosphatase activity|BCKDH phosphatase|phosphatase H-II|protein phosphatase type 1 activity|phosphatase I|serine/threonine specific protein phosphatase activity|phosphatase III|phosphatase II|HMG-CoA reductase phosphatase|protein D phosphatase|protein phosphatase type 4 activity|phosphatase SP|polycation modulated (PCM-) phosphatase|calcineurin|protein phosphatase type 1, intrinsic catalyst activity|phosphatase IB|protein phosphatase type 2A activity|protein phosphatase type 2B activity|branched-chain alpha-keto acid dehydrogenase phosphatase|protein phosphatase type 2C activity http://purl.obolibrary.org/obo/GO_0004722 GO:0004725 biolink:MolecularActivity protein tyrosine phosphatase activity Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. Reactome:R-HSA-8937767|Reactome:R-HSA-8864036|Reactome:R-HSA-74747|Reactome:R-HSA-997309|Reactome:R-HSA-8863804|Reactome:R-HSA-8867658|RHEA:10684|Reactome:R-HSA-8855381|Reactome:R-HSA-1169210|Reactome:R-HSA-8849435|Reactome:R-HSA-9636439|MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN|Reactome:R-HSA-8864125|Reactome:R-HSA-377643|Reactome:R-HSA-8852200|Reactome:R-HSA-203797|Reactome:R-HSA-914036|Reactome:R-HSA-9698408|Reactome:R-HSA-202214|Reactome:R-HSA-997326|Reactome:R-HSA-997314|Reactome:R-HSA-6807027|Reactome:R-HSA-74748|Reactome:R-HSA-8864029|Reactome:R-HSA-997311|Reactome:R-HSA-74733|Reactome:R-HSA-9635461|Reactome:R-HSA-389758|Reactome:R-HSA-6807008|Reactome:R-HSA-8867047|Reactome:R-HSA-1549564|EC:3.1.3.48|Reactome:R-HSA-877308|Reactome:R-HSA-1169188|Reactome:R-HSA-9603719|Reactome:R-HSA-445089|Reactome:R-HSA-1169192|Reactome:R-HSA-391868|Reactome:R-HSA-5683967 go-plus.json phosphotyrosine histone phosphatase activity|phosphoprotein phosphatase (phosphotyrosine) activity|tyrosine O-phosphate phosphatase activity|[phosphotyrosine]protein phosphatase activity|phosphotyrosylprotein phosphatase activity|PTPase activity|PTP-phosphatase activity|tyrosylprotein phosphatase activity|protein-tyrosine-phosphate phosphohydrolase activity|PPT-phosphatase activity|phosphotyrosine phosphatase activity|protein-tyrosine-phosphatase activity|protein phosphotyrosine phosphatase activity|phosphotyrosine protein phosphatase activity http://purl.obolibrary.org/obo/GO_0004725 GO:0004724 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004724 CHEBI:87061 biolink:ChemicalSubstance carbamate fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87061 GO:0004721 biolink:MolecularActivity phosphoprotein phosphatase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity. Reactome:R-HSA-174110|Reactome:R-HSA-1363276|Reactome:R-HSA-174124|Reactome:R-HSA-112383|MetaCyc:3.1.3.16-RXN|Reactome:R-HSA-167072|Reactome:R-HSA-178178|Reactome:R-HSA-2529015|Reactome:R-HSA-170161|Reactome:R-HSA-9636684|Reactome:R-HSA-170153|Reactome:R-HSA-170158|Reactome:R-HSA-1363274|Reactome:R-HSA-113503|Reactome:R-HSA-69199 go-plus.json protein phosphatase-2A activity|protein phosphatase-2B activity|protein phosphatase-2C activity|protein phosphatase-1 activity|protein phosphatase activity|phosphoprotein phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004721 CHEBI:87064 biolink:ChemicalSubstance benzimidazolylcarbamate fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87064 GO:0004720 biolink:MolecularActivity protein-lysine 6-oxidase activity Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide. RHEA:24544|Reactome:R-HSA-2395340|MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN|EC:1.4.3.13|Reactome:R-HSA-2002466|Reactome:R-HSA-2129375 go-plus.json protein-L-lysine:oxygen 6-oxidoreductase (deaminating)|lysyl oxidase activity http://purl.obolibrary.org/obo/GO_0004720 CHEBI:669 biolink:ChemicalSubstance 1-phenylethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_669 chebi_ph7_3 CHEBI:87068 biolink:ChemicalSubstance imidazole fungicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_87068 CHEBI:87069 biolink:ChemicalSubstance imidazole antifungal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_87069 GO:0004727 biolink:MolecularActivity prenylated protein tyrosine phosphatase activity Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0004727 GO:0004726 biolink:MolecularActivity non-membrane spanning protein tyrosine phosphatase activity Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate. Reactome:R-HSA-177924|Reactome:R-HSA-177923|Reactome:R-HSA-177926|Reactome:R-HSA-177935|Reactome:R-HSA-9635739 go-plus.json http://purl.obolibrary.org/obo/GO_0004726 CHEBI:53680 biolink:ChemicalSubstance dihalogenated L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_53680 GO:0004729 biolink:MolecularActivity oxygen-dependent protoporphyrinogen oxidase activity Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX. RHEA:25576|KEGG_REACTION:R03222|MetaCyc:PROTOPORGENOXI-RXN|EC:1.3.3.4|Reactome:R-HSA-189423 go-plus.json protoporphyrinogen-IX:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004729 GO:0004728 biolink:MolecularActivity obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. go-plus.json receptor signaling protein tyrosine phosphatase activity|receptor signalling protein tyrosine phosphatase activity http://purl.obolibrary.org/obo/GO_0004728 GO:0004734 biolink:MolecularActivity pyrimidodiazepine synthase activity Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione. RHEA:10720|MetaCyc:1.5.4.1-RXN|EC:1.5.4.1 go-plus.json PDA synthase activity|pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing) http://purl.obolibrary.org/obo/GO_0004734 GO:0004733 biolink:MolecularActivity pyridoxamine-phosphate oxidase activity Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide. MetaCyc:PMPOXI-RXN|RHEA:15817|Reactome:R-HSA-965019|EC:1.4.3.5|Reactome:R-HSA-965079 go-plus.json pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)|pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)|PMP oxidase activity|pyridoxine (pyridoxamine)phosphate oxidase activity|pyridoxine (pyridoxamine) 5'-phosphate oxidase activity|PdxH|pyridoxamine 5'-phosphate oxidase activity|pyridoxal 5'-phosphate synthase activity|pyridoxaminephosphate oxidase deaminating|pyridoxamine phosphate oxidase activity http://purl.obolibrary.org/obo/GO_0004733 GO:0004736 biolink:MolecularActivity pyruvate carboxylase activity Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate. Reactome:R-HSA-70501|RHEA:20844|MetaCyc:PYRUVATE-CARBOXYLASE-RXN|KEGG_REACTION:R00344|EC:6.4.1.1 go-plus.json pyruvate:carbon-dioxide ligase (ADP-forming)|pyruvic carboxylase activity http://purl.obolibrary.org/obo/GO_0004736 GO:0004735 biolink:MolecularActivity pyrroline-5-carboxylate reductase activity Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+. Reactome:R-HSA-6783939|Reactome:R-HSA-70664|RHEA:14109|Reactome:R-HSA-6783955|MetaCyc:PYRROLINECARBREDUCT-RXN|EC:1.5.1.2 go-plus.json L-proline-NAD(P)+ 5-oxidoreductase activity|1-pyrroline-5-carboxylate reductase activity|NADPH-L-delta1-pyrroline carboxylic acid reductase activity|L-proline:NAD(P)+ 5-oxidoreductase activity|L-proline oxidase activity|P5CR activity http://purl.obolibrary.org/obo/GO_0004735 CHEBI:87051 biolink:ChemicalSubstance 4alpha-methyl-5alpha-cholest-8-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87051 chebi_ph7_3 GO:0004730 biolink:MolecularActivity pseudouridylate synthase activity Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate. KEGG_REACTION:R01055|RHEA:18337|EC:4.2.1.70|MetaCyc:PSEUDOURIDYLATE-SYNTHASE-RXN go-plus.json pseudouridylate synthetase activity|pseudouridine monophosphate synthetase activity|pseudouridylic acid synthetase activity|pseudouridine-5'-phosphate glycosidase activity|uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)|uracil hydrolyase activity|psiUMP synthetase activity|5-ribosyluracil 5-phosphate synthetase activity|pseudouridine monophosphate synthase activity|uracil hydro-lyase (adding D-ribose 5-phosphate) http://purl.obolibrary.org/obo/GO_0004730 CHEBI:87050 biolink:ChemicalSubstance 4alpha-methyl-5alpha-cholest-8-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87050 chebi_ph7_3 CHEBI:38060 biolink:ChemicalSubstance triazine insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38060 GO:0004732 biolink:MolecularActivity pyridoxal oxidase activity Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide. RHEA:23724|EC:1.2.3.8|MetaCyc:PYRIDOXAL-OXIDASE-RXN go-plus.json pyridoxal:oxygen 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004732 CHEBI:87053 biolink:ChemicalSubstance 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87053 chebi_ph7_3 GO:0004731 biolink:MolecularActivity purine-nucleoside phosphorylase activity Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. Reactome:R-HSA-74242|Reactome:R-HSA-112034|Reactome:R-HSA-112033|RHEA:19805|Reactome:R-HSA-74249|EC:2.4.2.1|MetaCyc:PNP-RXN go-plus.json purine deoxyribonucleoside phosphorylase activity|PNPase activity|purine nucleoside phosphorylase activity|PUNPII|purine ribonucleoside phosphorylase activity|PUNPI|inosine-guanosine phosphorylase activity|inosine phosphorylase activity|purine-nucleoside:phosphate ribosyltransferase activity|purine deoxynucleoside phosphorylase activity http://purl.obolibrary.org/obo/GO_0004731 CHEBI:87055 biolink:ChemicalSubstance 3beta-hydroxy-5alpha-cholest-8-ene-4alpha-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_87055 chebi_ph7_3 CHEBI:87054 biolink:ChemicalSubstance 4alpha-formyl-5alpha-cholest-8-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87054 chebi_ph7_3 CHEBI:87056 biolink:ChemicalSubstance 5alpha-cholest-8-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_87056 chebi_ph7_3 CHEBI:87058 biolink:ChemicalSubstance lipid IIB(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87058 chebi_ph7_3 GO:0004738 biolink:MolecularActivity pyruvate dehydrogenase activity Catalysis of the oxidative decarboxylation of pyruvate. MetaCyc:PYRUVOXID-RXN|MetaCyc:RXN0-1134|Reactome:R-HSA-71397 go-plus.json pyruvic acid dehydrogenase activity|pyruvic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004738 GO:0004737 biolink:MolecularActivity pyruvate decarboxylase activity Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2. RHEA:11628|MetaCyc:PYRUVATE-DECARBOXYLASE-RXN|EC:4.1.1.1 go-plus.json alpha-ketoacid carboxylase activity|pyruvic decarboxylase activity|2-oxo-acid carboxy-lyase (aldehyde-forming)|2-oxo-acid carboxy-lyase activity|alpha-carboxylase activity http://purl.obolibrary.org/obo/GO_0004737 GO:0004739 biolink:MolecularActivity pyruvate dehydrogenase (acetyl-transferring) activity Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2. RHEA:19189|EC:1.2.4.1 go-plus.json PDH|MtPDC (mitochondrial pyruvate dehydogenase complex) activity|pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)|pyruvate dehydrogenase complex activity|pyruvate dehydrogenase (lipoamide) activity|pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity http://purl.obolibrary.org/obo/GO_0004739 CHEBI:87080 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87080 chebi_ph7_3 GO:0004701 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004701 GO:0004700 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004700 GO:0004703 biolink:MolecularActivity G protein-coupled receptor kinase activity Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate. RHEA:12008|EC:2.7.11.16 go-plus.json G-protein coupled receptor kinase activity|ATP:G-protein-coupled receptor phosphotransferase activity|G protein-coupled receptor kinase activity|GPCR kinase activity|GPCR phosphorylating protein kinase activity|G protein coupled receptor phosphorylating protein kinase activity|GRK6|GRK5|GRK4|G-protein-coupled receptor phosphorylating protein kinase activity|GPCRK|STK16 http://purl.obolibrary.org/obo/GO_0004703 CHEBI:87082 biolink:ChemicalSubstance 3-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_87082 chebi_ph7_3 GO:0004702 biolink:MolecularActivity obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. EC:2.7.11.- go-plus.json receptor signaling protein serine/threonine kinase activity|receptor signalling protein serine/threonine kinase activity http://purl.obolibrary.org/obo/GO_0004702 CHEBI:53666 biolink:ChemicalSubstance kaurane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53666 CHEBI:87089 biolink:ChemicalSubstance 2-O-(alpha-D-glucosyl)-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_87089 chebi_ph7_3 CHEBI:685 biolink:ChemicalSubstance 1-organyl-2-acetyl-sn-glycero-3-phospholipid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_685 chebi_ph7_3 CHEBI:38029 biolink:ChemicalSubstance carbohydrate sulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38029 CHEBI:38028 biolink:ChemicalSubstance cyanuric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38028 chebi_ph7_3 GO:0004709 biolink:MolecularActivity MAP kinase kinase kinase activity Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. Reactome:R-HSA-168184|Reactome:R-HSA-2730887|Reactome:R-HSA-450346|MetaCyc:2.7.11.25-RXN|Reactome:R-HSA-933530|Reactome:R-HSA-727819|EC:2.7.11.25|Reactome:R-HSA-450337|Reactome:R-HSA-451649|Reactome:R-HSA-392530 go-plus.json MAPK/ERK kinase kinase activity|MAP3K|MAPKKK activity|MEK kinase activity|MLK-like mitogen-activated protein triple kinase activity|MEKK3|REKS|MEKK2|MEKK1|MEKK|Mil/Raf|ATP:protein phosphotransferase (MAPKKKK-activated) activity|MLTK|cRaf|STK28|cMos|MLTKb|MEKK activity|mitogen-activated protein kinase kinase kinase activity|MLTKa http://purl.obolibrary.org/obo/GO_0004709 GO:0004708 biolink:MolecularActivity MAP kinase kinase activity Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate. Reactome:R-HSA-3238999|Reactome:R-HSA-448951|MetaCyc:2.7.12.2-RXN|Reactome:R-HSA-450333|Reactome:R-HSA-5218804|Reactome:R-HSA-1247960|EC:2.7.12.2 go-plus.json MAPKK activity|MEK activity|MAP2K|MAPKK1|MAPKK|STK27|mitogen-activated protein kinase kinase activity|MKK|MKK7|MKK6|MAP kinase kinase 4 activity|ATP:protein phosphotransferase (MAPKKK-activated) activity|MKK4|MAP kinase kinase 7 activity|MAP kinase or ERK kinase activity|ERK activator kinase activity|MKK2|MAPK activator activity|MEK2|MEK1 http://purl.obolibrary.org/obo/GO_0004708 CHEBI:53664 biolink:ChemicalSubstance dehydroglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53664 GO:0004705 biolink:MolecularActivity JUN kinase activity Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors. Reactome:R-HSA-204949|Reactome:R-HSA-205132|Reactome:R-HSA-9673789|Reactome:R-HSA-205075|Reactome:R-HSA-168136 go-plus.json SAPK1|JNK|JNK3alpha1|c-Jun N-terminal kinase activity http://purl.obolibrary.org/obo/GO_0004705 GO:0004704 biolink:MolecularActivity NF-kappaB-inducing kinase activity Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK). go-plus.json NIK http://purl.obolibrary.org/obo/GO_0004704 CHEBI:172880 biolink:ChemicalSubstance 5'-(N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_172880 GO:0004707 biolink:MolecularActivity MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. Reactome:R-HSA-445079|Reactome:R-HSA-5654566|KEGG_REACTION:R00162|Reactome:R-HSA-73722|MetaCyc:2.7.11.24-RXN|Reactome:R-HSA-5654565|Reactome:R-HSA-9626832|Reactome:R-HSA-5654562|Reactome:R-HSA-451366|EC:2.7.11.24|Reactome:R-HSA-5654560|Reactome:R-HSA-111898|Reactome:R-HSA-198733 go-plus.json SAP kinase activity|MBP kinase I activity|ERK1|ERK2|SAPK|MBP kinase II activity|stress-activated protein kinase activity|myelin basic protein kinase activity|ERK|stress-activated kinase activity|MAPK|ATP:protein phosphotransferase (MAPKK-activated) activity|extracellular signal-regulated kinase activity|MAP kinase 1 activity|MAP kinase 2 activity|mitogen-activated protein kinase activity|mitogen activated kinase activity http://purl.obolibrary.org/obo/GO_0004707 CHEBI:38024 biolink:ChemicalSubstance carboxyalkyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38024 GO:0004706 biolink:MolecularActivity JUN kinase kinase kinase activity Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs). go-plus.json JNKKK|JNK kinase kinase activity http://purl.obolibrary.org/obo/GO_0004706 CHEBI:38023 biolink:ChemicalSubstance 3-sulfolactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38023 GO:0004712 biolink:MolecularActivity protein serine/threonine/tyrosine kinase activity Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate. Reactome:R-HSA-6802924|Reactome:R-HSA-6802927|RHEA:46608|Reactome:R-HSA-9656212|Reactome:R-HSA-6802918|RHEA:17989|Reactome:R-HSA-6802921|Reactome:R-HSA-6802941|Reactome:R-HSA-6802910|RHEA:10596|Reactome:R-HSA-6802922|Reactome:R-HSA-5674373|Reactome:R-HSA-6802916|Reactome:R-HSA-5672969|EC:2.7.12.1 go-plus.json dual-specificity kinase activity|dual-specificity protein kinase|protein threonine/tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0004712 CHEBI:53659 biolink:ChemicalSubstance EC 1.4.3.22 (diamine oxidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_53659 GO:0004711 biolink:MolecularActivity ribosomal protein S6 kinase activity Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0004711 GO:0004714 biolink:MolecularActivity transmembrane receptor protein tyrosine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Reactome:R-HSA-8950537|Reactome:R-HSA-8986994|Reactome:R-HSA-8983371|Reactome:R-HSA-177933|EC:2.7.10.1|Reactome:R-HSA-169905|Reactome:R-HSA-8987042|Reactome:R-HSA-8987040|Reactome:R-HSA-8950591|Reactome:R-HSA-8950757|Reactome:R-HSA-8950453|Reactome:R-HSA-8983300|Reactome:R-HSA-8986995|Reactome:R-HSA-8987179|Reactome:R-HSA-8852552|Reactome:R-HSA-6784324|Reactome:R-HSA-8987096|Reactome:R-HSA-8950364|Reactome:R-HSA-8987084|Reactome:R-HSA-74715|Reactome:R-HSA-198295|Reactome:R-HSA-8987129|Reactome:R-HSA-8983424|Reactome:R-HSA-8982163|Reactome:R-HSA-74711|Reactome:R-HSA-8950485|Reactome:R-HSA-8950423|Reactome:R-HSA-8983309|Reactome:R-HSA-8987070|Reactome:R-HSA-8986985|Reactome:R-HSA-74742|Reactome:R-HSA-8987012|Reactome:R-HSA-8987202|Reactome:R-HSA-8950354|Reactome:R-HSA-8950269|Reactome:R-HSA-8987150|Reactome:R-HSA-167683|Reactome:R-HSA-8950340|Reactome:R-HSA-8950405|Reactome:R-HSA-167019|Reactome:R-HSA-166544|Reactome:R-HSA-8853792|MetaCyc:2.7.10.1-RXN|Reactome:R-HSA-8987255|Reactome:R-HSA-8987141 go-plus.json receptor protein tyrosine kinase activity|receptor protein-tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0004714 CHEBI:87071 biolink:ChemicalSubstance conazole antifungal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_87071 GO:0004713 biolink:MolecularActivity protein tyrosine kinase activity Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. Reactome:R-HSA-983709|Reactome:R-HSA-3215391|Reactome:R-HSA-2038944|Reactome:R-HSA-8848606|Reactome:R-HSA-1250195|Reactome:R-HSA-5655270|Reactome:R-HSA-8875451|Reactome:R-HSA-8849042|Reactome:R-HSA-2130194|Reactome:R-HSA-1839098|Reactome:R-HSA-1839110|Reactome:R-HSA-2029453|Reactome:R-HSA-982807|Reactome:R-HSA-452097|Reactome:R-HSA-445076|Reactome:R-HSA-2586555|Reactome:R-HSA-354124|Reactome:R-HSA-9673756|Reactome:R-HSA-177930|Reactome:R-HSA-8847977|Reactome:R-HSA-373747|Reactome:R-HSA-9665411|Reactome:R-HSA-9680248|Reactome:R-HSA-3928610|Reactome:R-HSA-8848005|Reactome:R-HSA-5218828|Reactome:R-HSA-451942|Reactome:R-HSA-8849463|Reactome:R-HSA-9018572|Reactome:R-HSA-8956659|Reactome:R-HSA-2730858|Reactome:R-HSA-8948143|Reactome:R-HSA-1963581|Reactome:R-HSA-8848124|Reactome:R-HSA-429441|Reactome:R-HSA-1168394|Reactome:R-HSA-9706344|Reactome:R-HSA-2730886|Reactome:R-HSA-205289|Reactome:R-HSA-9665704|Reactome:R-HSA-6806974|Reactome:R-HSA-9613023|Reactome:R-HSA-9664278|Reactome:R-HSA-5218809|Reactome:R-HSA-1247844|Reactome:R-HSA-399934|Reactome:R-HSA-9026579|Reactome:R-HSA-2029268|Reactome:R-HSA-909730|Reactome:R-HSA-2671850|Reactome:R-HSA-389083|Reactome:R-HSA-429449|Reactome:R-HSA-428888|Reactome:R-HSA-909718|Reactome:R-HSA-9698003|Reactome:R-HSA-372693|Reactome:R-HSA-909732|Reactome:R-HSA-8875817|Reactome:R-HSA-1470009|Reactome:R-HSA-2023460|Reactome:R-HSA-182969|Reactome:R-HSA-2424484|Reactome:R-HSA-8848818|Reactome:R-HSA-9034875|Reactome:R-HSA-8874082|Reactome:R-HSA-9664261|Reactome:R-HSA-170156|Reactome:R-HSA-9606159|Reactome:R-HSA-391866|Reactome:R-HSA-1963586|Reactome:R-HSA-9670412|Reactome:R-HSA-2671829|Reactome:R-HSA-9670418|Reactome:R-HSA-9699578|Reactome:R-HSA-2424487|Reactome:R-HSA-391156|Reactome:R-HSA-388831|RHEA:10596|Reactome:R-HSA-5654149|Reactome:R-HSA-2404199|Reactome:R-HSA-191636|Reactome:R-HSA-5654655|Reactome:R-HSA-1839112|Reactome:R-HSA-5357429|Reactome:R-HSA-5607750|Reactome:R-HSA-9032426|Reactome:R-HSA-1433454|Reactome:R-HSA-9032854|Reactome:R-HSA-8848077|Reactome:R-HSA-374701|Reactome:R-HSA-8983872|EC:2.7.10.2|Reactome:R-HSA-5654147|Reactome:R-HSA-2454208|Reactome:R-HSA-5654631|Reactome:R-HSA-3928583|Reactome:R-HSA-8937807|Reactome:R-HSA-9027272|Reactome:R-HSA-1248655|Reactome:R-HSA-1472121|Reactome:R-HSA-5624486|Reactome:R-HSA-4420117|Reactome:R-HSA-9028728|Reactome:R-HSA-2029459|Reactome:R-HSA-9027273|Reactome:R-HSA-5654407|Reactome:R-HSA-5218812|Reactome:R-HSA-8937728|Reactome:R-HSA-202168|Reactome:R-HSA-8964252|Reactome:R-HSA-8964242|Reactome:R-HSA-354073|Reactome:R-HSA-5654222|Reactome:R-HSA-1433542|Reactome:R-HSA-391865|Reactome:R-HSA-432129|Reactome:R-HSA-8876230|Reactome:R-HSA-9032601|Reactome:R-HSA-2012082|Reactome:R-HSA-202307|Reactome:R-HSA-112333|Reactome:R-HSA-2029989|Reactome:R-HSA-388833|Reactome:R-HSA-5655301|Reactome:R-HSA-873918|Reactome:R-HSA-8857925|Reactome:R-HSA-68954|Reactome:R-HSA-212710|Reactome:R-HSA-1225952|Reactome:R-HSA-391871|Reactome:R-HSA-8848758|Reactome:R-HSA-5218820|Reactome:R-HSA-9612996|Reactome:R-HSA-1839067|Reactome:R-HSA-2730862|Reactome:R-HSA-2730882|Reactome:R-HSA-190326|Reactome:R-HSA-5218851|Reactome:R-HSA-9606163|Reactome:R-HSA-177937|Reactome:R-HSA-5654428|Reactome:R-HSA-9703438|Reactome:R-HSA-508282|Reactome:R-HSA-5690702|Reactome:R-HSA-8853313|Reactome:R-HSA-879907|Reactome:R-HSA-1225960|Reactome:R-HSA-9665709|Reactome:R-HSA-4420128|Reactome:R-HSA-5654151|Reactome:R-HSA-2012087|Reactome:R-HSA-9665705|Reactome:R-HSA-9026890|Reactome:R-HSA-9664275|Reactome:R-HSA-5607745|Reactome:R-HSA-9625487|Reactome:R-HSA-202291|Reactome:R-HSA-2730888|Reactome:R-HSA-8849068|Reactome:R-HSA-418163|Reactome:R-HSA-3928594|Reactome:R-HSA-5654634|Reactome:R-HSA-5655243|Reactome:R-HSA-2395801|Reactome:R-HSA-377640|Reactome:R-HSA-443817|Reactome:R-HSA-5218640|Reactome:R-HSA-202165|Reactome:R-HSA-2029984|Reactome:R-HSA-1433506|Reactome:R-HSA-177934|Reactome:R-HSA-1888198|Reactome:R-HSA-1524186|Reactome:R-HSA-419646|Reactome:R-HSA-8874080|Reactome:R-HSA-380780|Reactome:R-HSA-2395412|Reactome:R-HSA-4420206|Reactome:R-HSA-1963582|Reactome:R-HSA-1433418|Reactome:R-HSA-5683930|Reactome:R-HSA-6790087|Reactome:R-HSA-2730884|Reactome:R-HSA-2730860|Reactome:R-HSA-2454239|Reactome:R-HSA-5655341|Reactome:R-HSA-202248|Reactome:R-HSA-202174|Reactome:R-HSA-418859|Reactome:R-HSA-373750|Reactome:R-HSA-2730833|Reactome:R-HSA-8874078|Reactome:R-HSA-445085|Reactome:R-HSA-8849102|Reactome:R-HSA-2424486|Reactome:R-HSA-5654408|Reactome:R-HSA-191062|Reactome:R-HSA-4093332|Reactome:R-HSA-418872|Reactome:R-HSA-9665032|Reactome:R-HSA-2033485|Reactome:R-HSA-5621355|Reactome:R-HSA-445091|Reactome:R-HSA-8937844|Reactome:R-HSA-9034714|Reactome:R-HSA-9695834|Reactome:R-HSA-9612085|Reactome:R-HSA-2586553|Reactome:R-HSA-399947|Reactome:R-HSA-8853309|Reactome:R-HSA-8857583|Reactome:R-HSA-5654605|Reactome:R-HSA-5654628|Reactome:R-HSA-1169421|Reactome:R-HSA-190408|Reactome:R-HSA-9029155|Reactome:R-HSA-114600|Reactome:R-HSA-9664976|Reactome:R-HSA-2033488|Reactome:R-HSA-2038387|Reactome:R-HSA-2404193|Reactome:R-HSA-69195|Reactome:R-HSA-9603420|Reactome:R-HSA-9006323|Reactome:R-HSA-5654545|Reactome:R-HSA-202233|Reactome:R-HSA-9026464|Reactome:R-HSA-9634390|Reactome:R-HSA-8867041|Reactome:R-HSA-1671691|Reactome:R-HSA-2033486|Reactome:R-HSA-873919|Reactome:R-HSA-9037040|Reactome:R-HSA-5654418|Reactome:R-HSA-171011|Reactome:R-HSA-9032532|Reactome:R-HSA-8848873|Reactome:R-HSA-8857577|Reactome:R-HSA-452100|Reactome:R-HSA-8851933|Reactome:R-HSA-5621363|Reactome:R-HSA-3928604|Reactome:R-HSA-5637796|Reactome:R-HSA-9606162|Reactome:R-HSA-170070|Reactome:R-HSA-1433488|Reactome:R-HSA-9021609|Reactome:R-HSA-389086|Reactome:R-HSA-202216|Reactome:R-HSA-2428926|Reactome:R-HSA-8848975|Reactome:R-HSA-5654582|Reactome:R-HSA-2730843|Reactome:R-HSA-983707|Reactome:R-HSA-9026502|Reactome:R-HSA-5218642|Reactome:R-HSA-190429|Reactome:R-HSA-2197698|Reactome:R-HSA-389354|Reactome:R-HSA-912629|Reactome:R-HSA-6784319|Reactome:R-HSA-5654578|Reactome:R-HSA-9029151|Reactome:R-HSA-9006332|Reactome:R-HSA-9669911|Reactome:R-HSA-5654587|Reactome:R-HSA-3928580|Reactome:R-HSA-190427|Reactome:R-HSA-210291|Reactome:R-HSA-879925|Reactome:R-HSA-2201322|Reactome:R-HSA-909729|Reactome:R-HSA-9703437|Reactome:R-HSA-1839065|Reactome:R-HSA-983703|Reactome:R-HSA-9024726|Reactome:R-HSA-9669890|Reactome:R-HSA-2033490|Reactome:R-HSA-183058|Reactome:R-HSA-2023455|Reactome:R-HSA-9026510|Reactome:R-HSA-2012073|Reactome:R-HSA-186786|Reactome:R-HSA-2671742|Reactome:R-HSA-1251922|Reactome:R-HSA-452122|Reactome:R-HSA-5654575|Reactome:R-HSA-9665389|Reactome:R-HSA-5655268|Reactome:R-HSA-4420121|Reactome:R-HSA-1295609|Reactome:R-HSA-5686587|Reactome:R-HSA-8848776|Reactome:R-HSA-434836|Reactome:R-HSA-1982066|Reactome:R-HSA-170991|Reactome:R-HSA-873924|Reactome:R-HSA-190413|Reactome:R-HSA-1307963|Reactome:R-HSA-3928578|Reactome:R-HSA-445084|Reactome:R-HSA-2395439|Reactome:R-HSA-9033284|Reactome:R-HSA-174164|Reactome:R-HSA-2730851|Reactome:R-HSA-8848726|Reactome:R-HSA-5655278|Reactome:R-HSA-8857555|Reactome:R-HSA-2396594|Reactome:R-HSA-9604767|Reactome:R-HSA-8853315|Reactome:R-HSA-5218830|Reactome:R-HSA-5218806|Reactome:R-HSA-1248694|Reactome:R-HSA-5654397|Reactome:R-HSA-190388|Reactome:R-HSA-9027425|Reactome:R-HSA-1250348|Reactome:R-HSA-9011241|Reactome:R-HSA-5654653|Reactome:R-HSA-389762|Reactome:R-HSA-9034814|Reactome:R-HSA-873922|Reactome:R-HSA-8876948|Reactome:R-HSA-1250315|Reactome:R-HSA-8853325|Reactome:R-HSA-9666425|Reactome:R-HSA-9672175|Reactome:R-HSA-9664588|Reactome:R-HSA-8848436|Reactome:R-HSA-8855237|Reactome:R-HSA-5655284|Reactome:R-HSA-9672173|Reactome:R-HSA-9698005|Reactome:R-HSA-8851890|Reactome:R-HSA-202245|Reactome:R-HSA-2029449|Reactome:R-HSA-8942607|Reactome:R-HSA-190385|Reactome:R-HSA-3928627|Reactome:R-HSA-399946|Reactome:R-HSA-9673761|Reactome:R-HSA-210872|Reactome:R-HSA-1295540|Reactome:R-HSA-5654607|Reactome:R-HSA-9012650|Reactome:R-HSA-6784006|Reactome:R-HSA-5637795|Reactome:R-HSA-909726|Reactome:R-HSA-8849032|Reactome:R-HSA-8876246|Reactome:R-HSA-5621370|Reactome:R-HSA-879909|Reactome:R-HSA-9706350|Reactome:R-HSA-3928648 go-plus.json protein-tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0004713 GO:0004710 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004710 CHEBI:87075 biolink:ChemicalSubstance O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87075 chebi_ph7_3 CHEBI:87079 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_87079 chebi_ph7_3 CHEBI:38038 biolink:ChemicalSubstance sulfuric amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_38038 CHEBI:38033 biolink:ChemicalSubstance acenaphthylenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_38033 GO:0004719 biolink:MolecularActivity protein-L-isoaspartate (D-aspartate) O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester. Reactome:R-HSA-5676966|RHEA:12705|EC:2.1.1.77|MetaCyc:2.1.1.77-RXN go-plus.json protein L-isoaspartyl methyltransferase activity|protein L-isoaspartate methyltransferase activity|protein D-aspartate methyltransferase activity|L-aspartyl/L-isoaspartyl protein methyltransferase activity|L-isoaspartyl protein carboxyl methyltransferase activity|D-aspartyl/L-isoaspartyl methyltransferase activity|protein beta-aspartate O-methyltransferase activity|protein (D-aspartate) methyltransferase activity|L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity|protein-L-isoaspartate O-methyltransferase activity|S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity|protein O-methyltransferase (L-isoaspartate)|protein-beta-aspartate O-methyltransferase activity|protein-L-isoaspartate(D-aspartate) O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0004719 CHEBI:38032 biolink:ChemicalSubstance carbotricyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_38032 CHEBI:38031 biolink:ChemicalSubstance carboxyalkanesulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_38031 GO:0004716 biolink:MolecularActivity obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. EC:2.7.10.- go-plus.json receptor signalling protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0004716 GO:0004715 biolink:MolecularActivity non-membrane spanning protein tyrosine kinase activity Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein. Reactome:R-HSA-1168459|Reactome:R-HSA-1295519|Reactome:R-HSA-1168423|Reactome:R-HSA-1112602|Reactome:R-HSA-453200|Reactome:R-HSA-432148|Reactome:R-HSA-437936|Reactome:R-HSA-6786095|EC:2.7.10.2|Reactome:R-HSA-1369115|Reactome:R-HSA-6786096|Reactome:R-HSA-1112703|Reactome:R-HSA-6788582|Reactome:R-HSA-1168767|Reactome:R-HSA-8871373|MetaCyc:2.7.10.2-RXN|Reactome:R-HSA-879910 go-plus.json focal adhesion kinase activity|cytoplasmic protein tyrosine kinase activity|janus kinase 1 activity|janus kinase 2 activity|janus kinase 3 activity|ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|ATP:protein-tyrosine O-phosphotransferase activity|non-specific protein-tyrosine kinase activity|p60c-src protein tyrosine kinase activity|Bruton's tyrosine kinase activity http://purl.obolibrary.org/obo/GO_0004715 CHEBI:38036 biolink:ChemicalSubstance sulfobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_38036 CHEBI:14086 biolink:ChemicalSubstance dTDP-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_14086 GO:0004718 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004718 CHEBI:53650 biolink:ChemicalSubstance guaiacylglycerol-beta-guaiacyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_53650 chebi_ph7_3 GO:0004717 biolink:MolecularActivity obsolete focal adhesion kinase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json focal adhesion kinase activity|FAK http://purl.obolibrary.org/obo/GO_0004717 CHEBI:38034 biolink:ChemicalSubstance aminonaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_38034 CHEBI:77619 biolink:ChemicalSubstance 1,3-dipalmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77619 chebi_ph7_3 CHEBI:77618 biolink:ChemicalSubstance norajmaline(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77618 chebi_ph7_3 CHEBI:77617 biolink:ChemicalSubstance senecionine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77617 chebi_ph7_3 GO:0038137 biolink:BiologicalProcess ERBB4-EGFR signaling pathway A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json ERBB4-EGFR signalling pathway|ERBB1-ERBB4 signaling pathway|HER1-HER4 signaling pathway http://purl.obolibrary.org/obo/GO_0038137 GO:0038136 biolink:BiologicalProcess ERBB3-ERBB4 signaling pathway A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json HER3-HER4 signaling pathway|ERBB3-ERBB4 signalling pathway http://purl.obolibrary.org/obo/GO_0038136 GO:0038139 biolink:CellularComponent ERBB4-EGFR complex A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1). go-plus.json ERBB4:EGFR heterodimer|EGFR-ERBB4 complex http://purl.obolibrary.org/obo/GO_0038139 GO:0038138 biolink:BiologicalProcess ERBB4-ERBB4 signaling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json HER4-HER4 signaling pathway|ERBB4 homodimeric signaling pathway|ERBB4-ERBB4 signalling pathway http://purl.obolibrary.org/obo/GO_0038138 CHEBI:133291 biolink:ChemicalSubstance saturated dicarboxylic acid dianion(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133291 chebi_ph7_3 GO:0038131 biolink:MolecularActivity neuregulin receptor activity Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json NRG receptor activity|NRG2 receptor activity|NRG1 receptor activity http://purl.obolibrary.org/obo/GO_0038131 GO:0038130 biolink:BiologicalProcess ERBB4 signaling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json HER4 signaling pathway|receptor tyrosine-protein kinase erbB-4 signaling pathway|ERBB4 signalling pathway http://purl.obolibrary.org/obo/GO_0038130 CHEBI:133292 biolink:ChemicalSubstance 3-oxo fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133292 chebi_ph7_3 CHEBI:77612 biolink:ChemicalSubstance cis,cis-2-ammonio-3-(3-oxoprop-1-enyl)but-2-enedioate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77612 chebi_ph7_3 GO:0038133 biolink:BiologicalProcess ERBB2-ERBB3 signaling pathway A series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission. go-plus.json ERBB2-ERBB3 signalling pathway|HER2-HER3 signaling pathway http://purl.obolibrary.org/obo/GO_0038133 CHEBI:77611 biolink:ChemicalSubstance monoalk-1-enyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77611 chebi_ph7_3 GO:0038132 biolink:MolecularActivity neuregulin binding Binding to a neuregulin, a member of the EGF family of growth factors. go-plus.json http://purl.obolibrary.org/obo/GO_0038132 CHEBI:133294 biolink:ChemicalSubstance oxo dicarboxylic acid dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133294 GO:0038135 biolink:BiologicalProcess ERBB2-ERBB4 signaling pathway A series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4. go-plus.json HER2-HER4 signaling pathway|ERBB2-ERBB4 signalling pathway http://purl.obolibrary.org/obo/GO_0038135 GO:0038134 biolink:BiologicalProcess ERBB2-EGFR signaling pathway A series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. go-plus.json EGFR-HER2 signaling pathway|ERBB2-EGFR signalling pathway http://purl.obolibrary.org/obo/GO_0038134 CHEBI:77624 biolink:ChemicalSubstance 1-palmitoyl-3-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77624 chebi_ph7_3 GO:0038126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038126 GO:0038125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0038125 GO:0038128 biolink:BiologicalProcess ERBB2 signaling pathway A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. go-plus.json HER2 signaling pathway|ERBB2 signalling pathway|receptor tyrosine-protein kinase erbB-2 signaling pathway|NEU signaling http://purl.obolibrary.org/obo/GO_0038128 GO:0038127 biolink:BiologicalProcess ERBB signaling pathway A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json EGFR family signaling pathway|ErbB signaling|EGF receptor family signaling pathway|ERBB signalling pathway http://purl.obolibrary.org/obo/GO_0038127 GO:0038129 biolink:BiologicalProcess ERBB3 signaling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission. go-plus.json ERBB3 signalling pathway|HER3 signaling pathway|receptor tyrosine-protein kinase erbB-3 signaling pathway http://purl.obolibrary.org/obo/GO_0038129 GO:0038120 biolink:BiologicalProcess CCL21-activated CCR7 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL21-activated CCR7 signalling pathway http://purl.obolibrary.org/obo/GO_0038120 GO:0038122 biolink:MolecularActivity C-C motif chemokine 5 receptor activity Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json small inducible cytokine A5 receptor activity|RANTES receptor activity|CCL5 receptor activity http://purl.obolibrary.org/obo/GO_0038122 CHEBI:77623 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-3-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77623 chebi_ph7_3 GO:0038121 biolink:MolecularActivity C-C motif chemokine 21 receptor activity Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json CCL21 receptor activity http://purl.obolibrary.org/obo/GO_0038121 CHEBI:77622 biolink:ChemicalSubstance 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77622 chebi_ph7_3 GO:0038124 biolink:BiologicalProcess toll-like receptor TLR6:TLR2 signaling pathway A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json toll-like receptor TLR6:TLR2 signalling pathway|TLR2:TLR6 signaling pathway http://purl.obolibrary.org/obo/GO_0038124 CHEBI:77621 biolink:ChemicalSubstance 2',3,4,4',6'-pentahydroxychalcone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77621 chebi_ph7_3 GO:0038123 biolink:BiologicalProcess toll-like receptor TLR1:TLR2 signaling pathway A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json TLR2:TLR1 signaling pathway|toll-like receptor TLR1:TLR2 signalling pathway http://purl.obolibrary.org/obo/GO_0038123 CHEBI:77620 biolink:ChemicalSubstance 5-oxido-6-methylpyridinium-3,4-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77620 chebi_ph7_3 CHEBI:77638 biolink:ChemicalSubstance dihydrophloroglucinol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77638 chebi_ph7_3 CHEBI:77636 biolink:ChemicalSubstance fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77636 chebi_ph7_3 CHEBI:77639 biolink:ChemicalSubstance sulochrin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77639 chebi_ph7_3 GO:0038115 biolink:BiologicalProcess chemokine (C-C motif) ligand 19 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL19-mediated signaling pathway|C-C chemokine receptor type 7 signaling pathway|chemokine (C-C motif) ligand 19 signalling pathway http://purl.obolibrary.org/obo/GO_0038115 GO:0038114 biolink:BiologicalProcess interleukin-21-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-21-mediated signalling pathway|IL-21-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038114 GO:0038117 biolink:MolecularActivity C-C motif chemokine 19 receptor activity Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json CCL19 receptor activity http://purl.obolibrary.org/obo/GO_0038117 GO:0038116 biolink:BiologicalProcess chemokine (C-C motif) ligand 21 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL21-mediated signaling pathway|chemokine (C-C motif) ligand 21 signalling pathway|C-C chemokine receptor type 7 signaling pathway http://purl.obolibrary.org/obo/GO_0038116 GO:0038119 biolink:BiologicalProcess CCL19-activated CCR7 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CCL19-activated CCR7 signalling pathway http://purl.obolibrary.org/obo/GO_0038119 GO:0038118 biolink:BiologicalProcess C-C chemokine receptor CCR7 signaling pathway A series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json C-C chemokine receptor CCR7 signalling pathway|CCR7 signaling pathway http://purl.obolibrary.org/obo/GO_0038118 CHEBI:77630 biolink:ChemicalSubstance trans-2-pentadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77630 GO:0038111 biolink:BiologicalProcess interleukin-7-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-7-mediated signalling pathway|IL-7-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038111 CHEBI:77634 biolink:ChemicalSubstance 2-aminomuconic 6-semialdehyde zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77634 chebi_ph7_3 GO:0038110 biolink:BiologicalProcess interleukin-2-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-2-mediated signalling pathway|IL-2-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038110 CHEBI:77633 biolink:ChemicalSubstance isonocardicin A(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77633 chebi_ph7_3 GO:0038113 biolink:BiologicalProcess interleukin-9-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-9-mediated signaling pathway|interleukin-9-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0038113 CHEBI:77632 biolink:ChemicalSubstance unsaturated fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77632 GO:0038112 biolink:BiologicalProcess interleukin-8-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json interleukin-8-mediated signalling pathway|IL-8-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0038112 CHEBI:77631 biolink:ChemicalSubstance 1-piperideine-2-carboxylic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77631 chebi_ph7_3 CHEBI:77648 biolink:ChemicalSubstance novapikromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77648 CHEBI:77647 biolink:ChemicalSubstance 2,3',4,6-tetrahydroxybenzophenone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77647 chebi_ph7_3 CHEBI:77646 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77646 CHEBI:63001 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_63001 chebi_ph7_3 GO:0038104 biolink:CellularComponent nodal receptor complex A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell. go-plus.json ActRIIB.ALK4.EGF-CFC complex http://purl.obolibrary.org/obo/GO_0038104 GO:0038103 biolink:MolecularActivity activin receptor antagonist activity involved in negative regulation of nodal signaling pathway Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor. go-plus.json nodal antagonist activity|activin receptor antagonist activity involved in negative regulation of nodal signalling pathway http://purl.obolibrary.org/obo/GO_0038103 GO:0038106 biolink:MolecularActivity choriogonadotropin hormone binding Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit. go-plus.json chorionic gonadotropin binding|chorionic gonadotrophin binding http://purl.obolibrary.org/obo/GO_0038106 GO:0038105 biolink:BiologicalProcess sequestering of TGFbeta from receptor via TGFbeta binding Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor. go-plus.json extracellular sequestering of transforming growth factor-beta|extracellular sequestering of TGFbeta http://purl.obolibrary.org/obo/GO_0038105 GO:0038108 biolink:BiologicalProcess negative regulation of appetite by leptin-mediated signaling pathway A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food. go-plus.json reduction of appetite by leptin-mediated signaling|inhibition of appetite by leptin signaling|suppression of appetite by leptin-mediated signaling pathway|negative regulation of appetite by leptin-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0038108 GO:0038107 biolink:BiologicalProcess nodal signaling pathway involved in determination of left/right asymmetry A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves. go-plus.json nodal signalling pathway involved in determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter by nodal signaling pathway, involved in determination of left/right symmetry http://purl.obolibrary.org/obo/GO_0038107 GO:0038109 biolink:BiologicalProcess Kit signaling pathway A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell. go-plus.json Kit signalling pathway|stem cell factor signaling pathway|SCF signaling pathway|stem cell factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0038109 CHEBI:77641 biolink:ChemicalSubstance anthocyanidin 3,5-diglucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77641 chebi_ph7_3 CHEBI:77640 biolink:ChemicalSubstance apiin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77640 chebi_ph7_3 GO:0038100 biolink:MolecularActivity nodal binding Binding to a nodal protein, a member of the transforming growth factor-beta superfamily. go-plus.json http://purl.obolibrary.org/obo/GO_0038100 CHEBI:77645 biolink:ChemicalSubstance 2',4,4',6'-tetrahydroxychalcone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77645 chebi_ph7_3 CHEBI:77644 biolink:ChemicalSubstance 5-L-glutamyl amino acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77644 chebi_ph7_3 CHEBI:77643 biolink:ChemicalSubstance protoaphin aglucone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77643 chebi_ph7_3 GO:0038102 biolink:MolecularActivity activin receptor antagonist activity Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0038102 GO:0038101 biolink:BiologicalProcess sequestering of nodal from receptor via nodal binding Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor. go-plus.json nodal antagonist activity|extracellular regulation of nodal|binding to and sequestering nodal http://purl.obolibrary.org/obo/GO_0038101 CHEBI:77642 biolink:ChemicalSubstance 2'-O-methyllicodione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77642 chebi_ph7_3 CHEBI:77659 biolink:ChemicalSubstance emodin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77659 chebi_ph7_3 CHEBI:77658 biolink:ChemicalSubstance nocardicin A(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77658 chebi_ph7_3 CHEBI:77657 biolink:ChemicalSubstance 5-amino-1-(5-phosphonato-D-ribosyl)imidazolium-4-carboxylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77657 chebi_ph7_3 CHEBI:77652 biolink:ChemicalSubstance novamethymycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77652 NCBITaxon:1489100 biolink:OrganismalEntity Holostei go-plus.json bowfins and gars http://purl.obolibrary.org/obo/NCBITaxon_1489100 CHEBI:133251 biolink:ChemicalSubstance 3-hydroxydicarboxylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133251 chebi_ph7_3 CHEBI:77656 biolink:ChemicalSubstance 4-oxoproline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77656 chebi_ph7_3 CHEBI:77654 biolink:ChemicalSubstance EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77654 CHEBI:77653 biolink:ChemicalSubstance (3R)-3-carboxy-3-hydroxypropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77653 CHEBI:77663 biolink:ChemicalSubstance pulcherriminate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77663 chebi_ph7_3 CHEBI:77662 biolink:ChemicalSubstance L-3-oxoalanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77662 chebi_ph7_3 CHEBI:77660 biolink:ChemicalSubstance pyrroloquinoline quinol(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77660 chebi_ph7_3 CHEBI:77667 biolink:ChemicalSubstance 2,4-divinyl protochlorophyllide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77667 GO:0004789 biolink:MolecularActivity thiamine-phosphate diphosphorylase activity Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate. MetaCyc:THI-P-SYN-RXN|RHEA:22328|KEGG_REACTION:R03223|EC:2.5.1.3 go-plus.json TMP pyrophosphorylase activity|thiamine-phosphate pyrophosphorylase activity|TMP diphosphorylase activity|thiamine monophosphate pyrophosphorylase activity|TMP-PPase activity|thiamine phosphate pyrophosphorylase activity|2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamin-phosphate pyrophosphorylase activity|thiamin-phosphate diphosphorylase activity|thiamine-phosphate synthase activity http://purl.obolibrary.org/obo/GO_0004789 GO:0004788 biolink:MolecularActivity thiamine diphosphokinase activity Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate. MetaCyc:THIAMIN-PYROPHOSPHOKINASE-RXN|RHEA:11576|EC:2.7.6.2|Reactome:R-HSA-196761 go-plus.json thiaminokinase activity|thiamin pyrophosphotransferase activity|ATP:thiamine diphosphotransferase activity|thiamine pyrophosphokinase activity|TPTase activity|thiamin pyrophosphokinase activity|thiamin diphosphokinase activity|thiamin:ATP pyrophosphotransferase activity|ATP:thiamin pyrophosphotransferase activity http://purl.obolibrary.org/obo/GO_0004788 CHEBI:77679 biolink:ChemicalSubstance 1-hexadecyl-2-acetyl-3-decanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77679 chebi_ph7_3 GO:0004785 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004785 GO:0004784 biolink:MolecularActivity superoxide dismutase activity Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide. Reactome:R-HSA-3299680|MetaCyc:SUPEROX-DISMUT-RXN|Reactome:R-HSA-3299691|Reactome:R-HSA-3299682|Reactome:R-HSA-3777112|Reactome:R-HSA-1222469|RHEA:20696|Reactome:R-HSA-1222462|EC:1.15.1.1 go-plus.json nickel superoxide dismutase activity|erythrocuprein|hemocuprein|iron superoxide dismutase activity|cuprein|ferrisuperoxide dismutase activity|SOD-4|SOD-3|SOD-2|hepatocuprein|Cu-Zn superoxide dismutase activity|manganese superoxide dismutase activity|SOD-1|superoxide:superoxide oxidoreductase activity|SODS|Cu,Zn-SOD|SOD|nickel superoxide oxidoreductase|iron superoxide oxidoreductase|superoxide dismutase II|cytocuprein|superoxide dismutase I|zinc superoxide oxidoreductase|Mn, Fe superoxide dismutase|copper, zinc superoxide dismutase activity|SODF|Mn-SOD|manganese superoxide oxidoreductase|Fe-SOD http://purl.obolibrary.org/obo/GO_0004784 GO:0004787 biolink:MolecularActivity thiamine-diphosphatase activity Catalysis of the reaction: TPP + H2O = TMP + phosphate. RHEA:27998 go-plus.json thiamin pyrophosphatase activity|thiamin-pyrophosphatase activity|TPPase activity|thiamine pyrophosphatase activity|thiaminpyrophosphatase activity http://purl.obolibrary.org/obo/GO_0004787 GO:0004786 biolink:MolecularActivity obsolete Mn, Fe superoxide dismutase OBSOLETE. (Was not defined before being made obsolete). go-plus.json Mn, Fe superoxide dismutase http://purl.obolibrary.org/obo/GO_0004786 GO:0004781 biolink:MolecularActivity sulfate adenylyltransferase (ATP) activity Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate. Reactome:R-HSA-174392|EC:2.7.7.4|MetaCyc:SULFATE-ADENYLYLTRANS-RXN|RHEA:18133|Reactome:R-HSA-3560794 go-plus.json ATP:sulfate adenylyltransferase activity|sulfate adenylate transferase activity|ATP-sulfurylase activity|adenosine-5'-triphosphate sulfurylase activity|sulphate adenylyltransferase (ATP) activity|ATP sulfurylase activity|adenylylsulfate pyrophosphorylase activity|sulfurylase activity|adenosinetriphosphate sulfurylase activity http://purl.obolibrary.org/obo/GO_0004781 CHEBI:87000 biolink:ChemicalSubstance 1-acyl-2-[(7Z)-hexadec-7-enoyl]-glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87000 chebi_ph7_3 GO:0004780 biolink:MolecularActivity sulfate adenylyltransferase (ADP) activity Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate. RHEA:16529|EC:2.7.7.5|KEGG_REACTION:R00530|MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN go-plus.json adenosine diphosphate sulfurylase activity|sulfate (adenosine diphosphate) adenylyltransferase activity|ADP:sulfate adenylyltransferase activity|ADP-sulfurylase activity|sulphate adenylyltransferase (ADP) activity http://purl.obolibrary.org/obo/GO_0004780 GO:0004783 biolink:MolecularActivity sulfite reductase (NADPH) activity Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+. MetaCyc:SULFITE-REDUCT-RXN|RHEA:13801|EC:1.8.1.2 go-plus.json NADPH-dependent sulfite reductase activity|NADPH:sulfite reductase flavoprotein|NADPH-sulfite reductase activity|sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|hydrogen-sulfide:NADP+ oxidoreductase activity|sulphite reductase (NADPH) activity|H2S-NADP oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004783 CHEBI:87002 biolink:ChemicalSubstance 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87002 chebi_ph7_3 GO:0004782 biolink:MolecularActivity sulfinoalanine decarboxylase activity Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2. EC:4.1.1.29|RHEA:16877|Reactome:R-HSA-1655443|MetaCyc:SULFINOALANINE-DECARBOXYLASE-RXN go-plus.json CSADCase activity|cysteinesulfinate decarboxylase activity|3-sulfino-L-alanine carboxy-lyase activity|3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)|cysteic decarboxylase activity|L-cysteinesulfinic acid decarboxylase activity|cysteinesulfinic acid decarboxylase activity|CSAD|CADCase/CSADCase activity|sulfoalanine decarboxylase activity|cysteine-sulfinate decarboxylase activity|sulphinoalanine decarboxylase activity http://purl.obolibrary.org/obo/GO_0004782 CHEBI:87003 biolink:ChemicalSubstance 1-acyl-2-palmitoleoylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87003 chebi_ph7_3 CHEBI:87008 biolink:ChemicalSubstance 1-oleoyl-2-acylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87008 chebi_ph7_3 CHEBI:87007 biolink:ChemicalSubstance 1-stearoyl 2-acylglycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_87007 chebi_ph7_3 CHEBI:77670 biolink:ChemicalSubstance primary fluorescent chlorophyll catabolite(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77670 chebi_ph7_3 CHEBI:77674 biolink:ChemicalSubstance queuine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77674 chebi_ph7_3 CHEBI:77673 biolink:ChemicalSubstance N-acyl-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77673 CHEBI:77672 biolink:ChemicalSubstance N-acyl-D-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77672 CHEBI:77671 biolink:ChemicalSubstance luteolin 7-O-beta-D-glucosiduronate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77671 chebi_ph7_3 CHEBI:77678 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-myristoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77678 chebi_ph7_3 CHEBI:77677 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77677 chebi_ph7_3 CHEBI:77676 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77676 chebi_ph7_3 GO:0004799 biolink:MolecularActivity thymidylate synthase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. RHEA:12104|KEGG_REACTION:R02101|Reactome:R-HSA-73605|MetaCyc:THYMIDYLATESYN-RXN|EC:2.1.1.45 go-plus.json 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity|methylenetetrahydrofolate:dUMP C-methyltransferase activity|dTMP synthase activity|thymidylate synthetase activity|TMP synthetase activity http://purl.obolibrary.org/obo/GO_0004799 GO:0004796 biolink:MolecularActivity thromboxane-A synthase activity Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2). KEGG_REACTION:R02268|RHEA:17137|Reactome:R-HSA-5603275|Reactome:R-HSA-76500|EC:5.3.99.5|MetaCyc:THROMBOXANE-A-SYNTHASE-RXN go-plus.json (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity|cytochrome P450 CYP5|thromboxane synthetase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity|thromboxane synthase activity http://purl.obolibrary.org/obo/GO_0004796 GO:0004795 biolink:MolecularActivity threonine synthase activity Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate. RHEA:10840|MetaCyc:THRESYN-RXN|EC:4.2.3.1 go-plus.json threonine synthetase activity|O-phospho-L-homoserine phospho-lyase (adding water)|O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming) http://purl.obolibrary.org/obo/GO_0004795 GO:0004798 biolink:MolecularActivity thymidylate kinase activity Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate. RHEA:13517|EC:2.7.4.9|MetaCyc:DTMPKI-RXN go-plus.json ATP:dTMP phosphotransferase activity|thymidine 5'-monophosphate kinase activity|thymidine monophosphate kinase activity|thymidylate monophosphate kinase activity|dTMP kinase activity|deoxythymidine 5'-monophosphate kinase activity|thymidylic kinase activity|TMPK activity|thymidylic acid kinase activity http://purl.obolibrary.org/obo/GO_0004798 GO:0004797 biolink:MolecularActivity thymidine kinase activity Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate. MetaCyc:THYKI-RXN|EC:2.7.1.21|RHEA:19129 go-plus.json ATP:thymidine 5'-phosphotransferase activity|deoxythymidine kinase (phosphorylating)|thymidine kinase (phosphorylating)|2'-deoxythymidine kinase activity http://purl.obolibrary.org/obo/GO_0004797 GO:0004792 biolink:MolecularActivity thiosulfate sulfurtransferase activity Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate. MetaCyc:THIOSULFATE-SULFURTRANSFERASE-RXN|Reactome:R-HSA-9013198|EC:2.8.1.1|RHEA:16881|KEGG_REACTION:R01931 go-plus.json thiosulphate sulphurtransferase activity|thiosulfate thiotransferase activity|thiosulfate cyanide transsulfurase activity|thiosulfate:cyanide sulfurtransferase activity|rhodanase activity|rhodanese activity http://purl.obolibrary.org/obo/GO_0004792 GO:0004791 biolink:MolecularActivity thioredoxin-disulfide reductase activity Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide. RHEA:20345|Reactome:R-HSA-3323050|EC:1.8.1.9|KEGG_REACTION:R02016|Reactome:R-HSA-9617735|Reactome:R-HSA-1222485|MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN|Reactome:R-HSA-73646 go-plus.json NADP--thioredoxin reductase activity|NADPH2:oxidized thioredoxin oxidoreductase activity|NADPH:oxidized thioredoxin oxidoreductase activity|thioredoxin reductase (NADPH) activity|thioredoxin disulfide reductase activity|thioredoxin-disulphide reductase activity|NADPH--thioredoxin reductase activity|thioredoxin:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004791 CHEBI:615 biolink:ChemicalSubstance 1-carbapenem-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_615 GO:0004794 biolink:MolecularActivity L-threonine ammonia-lyase activity Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3. UM-BBD_reactionID:r0433|EC:4.3.1.19|MetaCyc:THREDEHYD-RXN|RHEA:22108 go-plus.json L-threonine hydro-lyase (deaminating) activity|L-threonine dehydratase activity|L-threonine deaminase activity|threonine deaminase activity|L-serine dehydratase activity|serine deaminase activity|threonine ammonia-lyase activity|threonine dehydrase activity|L-threonine ammonia-lyase (2-oxobutanoate-forming)|threonine dehydratase activity http://purl.obolibrary.org/obo/GO_0004794 GO:0004793 biolink:MolecularActivity threonine aldolase activity Catalysis of the reaction: L-threonine = glycine + acetaldehyde. RHEA:19625|EC:4.1.2.5|MetaCyc:THREONINE-ALDOLASE-RXN go-plus.json L-threonine aldolase activity|L-threonine acetaldehyde-lyase activity|L-threonine acetaldehyde-lyase (glycine-forming) http://purl.obolibrary.org/obo/GO_0004793 CHEBI:63048 biolink:ChemicalSubstance 1,3-thiazolium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_63048 CHEBI:63047 biolink:ChemicalSubstance food emulsifier go-plus.json http://purl.obolibrary.org/obo/CHEBI_63047 GO:0004790 biolink:MolecularActivity thioether S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium. RHEA:19613|KEGG_REACTION:R02572|MetaCyc:THIOETHER-S-METHYLTRANSFERASE-RXN|EC:2.1.1.96 go-plus.json thioether methyltransferase activity|S-adenosyl-L-methionine:thioether S-methyltransferase activity|S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity http://purl.obolibrary.org/obo/GO_0004790 CHEBI:63046 biolink:ChemicalSubstance emulsifier go-plus.json http://purl.obolibrary.org/obo/CHEBI_63046 CHEBI:133243 biolink:ChemicalSubstance O-[S-(long-chain fatty acyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133243 chebi_ph7_3 CHEBI:77681 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-lauroyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77681 chebi_ph7_3 CHEBI:77680 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-palmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77680 chebi_ph7_3 CHEBI:133249 biolink:ChemicalSubstance saturated fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_133249 chebi_ph7_3 CHEBI:77685 biolink:ChemicalSubstance 1,2-dioleoyl-3-lauroyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77685 chebi_ph7_3 CHEBI:77684 biolink:ChemicalSubstance 1,2-dioleoyl-3-myristoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77684 chebi_ph7_3 CHEBI:77683 biolink:ChemicalSubstance 1,2-dioleoyl-3-linoleoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77683 chebi_ph7_3 CHEBI:77682 biolink:ChemicalSubstance 1-palmityl-2-acetyl-3-capryloyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77682 chebi_ph7_3 CHEBI:77689 biolink:ChemicalSubstance L-mimosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77689 chebi_ph7_3 CHEBI:77688 biolink:ChemicalSubstance formononetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77688 chebi_ph7_3 CHEBI:133242 biolink:ChemicalSubstance O-[S-(medium-chain fatty acyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133242 chebi_ph7_3 CHEBI:77687 biolink:ChemicalSubstance 2'-hydroxyformononetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77687 chebi_ph7_3 CHEBI:133241 biolink:ChemicalSubstance omega-carboxyacyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133241 chebi_ph7_3 CHEBI:77686 biolink:ChemicalSubstance 1,2-dioleoyl-3-stearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77686 chebi_ph7_3 CHEBI:28607 biolink:ChemicalSubstance coproporphyrinogen I go-plus.json http://purl.obolibrary.org/obo/CHEBI_28607 CHEBI:28600 biolink:ChemicalSubstance farnesol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28600 chebi_ph7_3 CHEBI:28602 biolink:ChemicalSubstance beta-D-fructofuranose 2,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28602 CHEBI:28609 biolink:ChemicalSubstance N-benzoyl-4-methoxyanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28609 CHEBI:28616 biolink:ChemicalSubstance carbamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28616 CHEBI:28618 biolink:ChemicalSubstance 1,4-dichlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28618 chebi_ph7_3 NCBITaxon:41827 biolink:OrganismalEntity Culicoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_41827 CHEBI:28610 biolink:ChemicalSubstance 1-O-oleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28610 chebi_ph7_3 CHEBI:28619 biolink:ChemicalSubstance acrylamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28619 chebi_ph7_3 CARO:0000000 biolink:OntologyClass anatomical entity go-plus.json http://purl.obolibrary.org/obo/CARO_0000000 CARO:0000003 biolink:OntologyClass connected anatomical structure go-plus.json http://purl.obolibrary.org/obo/CARO_0000003 CARO:0000007 biolink:OntologyClass immaterial anatomical entity go-plus.json http://purl.obolibrary.org/obo/CARO_0000007 CARO:0000006 biolink:OntologyClass material anatomical entity go-plus.json http://purl.obolibrary.org/obo/CARO_0000006 CHEBI:77609 biolink:ChemicalSubstance monoalk-1-enyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77609 chebi_ph7_3 GO:0004921 biolink:MolecularActivity interleukin-11 receptor activity Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-11R|gp130|IL-11 receptor activity http://purl.obolibrary.org/obo/GO_0004921 GO:0004920 biolink:MolecularActivity interleukin-10 receptor activity Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-10R|IL-10 receptor activity http://purl.obolibrary.org/obo/GO_0004920 GO:0004923 biolink:MolecularActivity leukemia inhibitory factor receptor activity Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json leukemia inhibitory factor receptor beta-protein activity|LIF receptor activity http://purl.obolibrary.org/obo/GO_0004923 CHEBI:28689 biolink:ChemicalSubstance dehydroepiandrosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28689 chebi_ph7_3 CHEBI:53647 biolink:ChemicalSubstance dehydroglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_53647 CHEBI:28685 biolink:ChemicalSubstance molybdenum atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_28685 chebi_ph7_3 CHEBI:28684 biolink:ChemicalSubstance 4-acetamidobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28684 CHEBI:28681 biolink:ChemicalSubstance N,N'-diacetylchitobiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28681 chebi_ph7_3 CHEBI:28680 biolink:ChemicalSubstance cytarabine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28680 chebi_ph7_3 CHEBI:28683 biolink:ChemicalSubstance kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28683 GO:0004929 biolink:MolecularActivity obsolete frizzled-2 receptor activity OBSOLETE. Combining with to a member of the Wnt-family of signaling molecules to initiate a change in cell activity. go-plus.json frizzled-2 receptor activity http://purl.obolibrary.org/obo/GO_0004929 NCBITaxon:51240 biolink:OrganismalEntity Juglans regia go-plus.json English walnut http://purl.obolibrary.org/obo/NCBITaxon_51240 NCBITaxon:6960 biolink:OrganismalEntity Hexapoda go-plus.json hexapods|Atelocerata|Tracheata|insects|Uniramia http://purl.obolibrary.org/obo/NCBITaxon_6960 GO:0004928 biolink:MolecularActivity obsolete frizzled receptor activity OBSOLETE. Combining with a member of the Wnt-family of signaling molecules to initiate a change in cell activity. go-plus.json frizzled receptor activity http://purl.obolibrary.org/obo/GO_0004928 CHEBI:53643 biolink:ChemicalSubstance phyllocladan-16alpha-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_53643 chebi_ph7_3 GO:0004925 biolink:MolecularActivity prolactin receptor activity Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004925 GO:0004924 biolink:MolecularActivity oncostatin-M receptor activity Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004924 GO:0004927 biolink:MolecularActivity obsolete sevenless receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json sevenless receptor activity http://purl.obolibrary.org/obo/GO_0004927 CHEBI:7466 biolink:ChemicalSubstance nandrolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_7466 chebi_ph7_3 CHEBI:14030 biolink:ChemicalSubstance crepenynate go-plus.json http://purl.obolibrary.org/obo/CHEBI_14030 chebi_ph7_3 GO:0004926 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004926 CHEBI:38001 biolink:ChemicalSubstance 2,6-diaminopurines go-plus.json http://purl.obolibrary.org/obo/CHEBI_38001 GO:0004932 biolink:MolecularActivity mating-type factor pheromone receptor activity Combining with a mating-type factor pheromone to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004932 GO:0004931 biolink:MolecularActivity extracellularly ATP-gated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. Reactome:R-HSA-877187 go-plus.json P2X receptor|purinoceptor|purinoreceptor http://purl.obolibrary.org/obo/GO_0004931 GO:0004934 biolink:MolecularActivity mating-type alpha-factor pheromone receptor activity Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity. go-plus.json class D G-protein coupled receptor activity|class D G-protein-coupled receptor activity|class D G protein coupled receptor activity|class D GPCR activity http://purl.obolibrary.org/obo/GO_0004934 GO:0004933 biolink:MolecularActivity mating-type a-factor pheromone receptor activity Combining with the mating-type a-factor pheromone to initiate a change in cell activity. go-plus.json class D G-protein coupled receptor activity|class D G-protein-coupled receptor activity|class D G protein coupled receptor activity|class D GPCR activity http://purl.obolibrary.org/obo/GO_0004933 CHEBI:53634 biolink:ChemicalSubstance neomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_53634 CHEBI:28699 biolink:ChemicalSubstance cyclic 2,3-bisphospho-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28699 GO:0004930 biolink:MolecularActivity G protein-coupled receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. Reactome:R-HSA-114552|Wikipedia:GPCR|Reactome:R-HSA-167408|Reactome:R-HSA-114558 go-plus.json orphan GPCR activity|Epstein-Barr Virus-induced receptor activity|G protein linked receptor activity|orphan G-protein coupled receptor activity|G protein coupled receptor activity|Mas proto-oncogene receptor activity|super conserved receptor expressed in brain receptor activity|RDC1 receptor activity|GPCR activity|ligand-dependent GPCR activity|G-protein coupled receptor activity|G-protein coupled receptor activity, unknown ligand|G-protein linked receptor activity|orphan G protein coupled receptor activity|EBV-induced receptor|receptor activity, G-protein coupled|SREB receptor http://purl.obolibrary.org/obo/GO_0004930 goslim_chembl CHEBI:28697 biolink:ChemicalSubstance 21-deoxycortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28697 chebi_ph7_3 CHEBI:28691 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28691 chebi_ph7_3 CHEBI:28694 biolink:ChemicalSubstance copper atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_28694 chebi_ph7_3 CHEBI:14027 biolink:ChemicalSubstance corydaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_14027 chebi_ph7_3 CHEBI:598 biolink:ChemicalSubstance 1-alkyl-2-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_598 chebi_ph7_3 GO:0004939 biolink:MolecularActivity beta-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein. go-plus.json beta adrenoceptor http://purl.obolibrary.org/obo/GO_0004939 GO:0004936 biolink:MolecularActivity alpha-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors. go-plus.json alpha adrenoceptor http://purl.obolibrary.org/obo/GO_0004936 GO:0004935 biolink:MolecularActivity adrenergic receptor activity Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex. Wikipedia:Adrenergic_receptor go-plus.json adrenoceptor activity http://purl.obolibrary.org/obo/GO_0004935 GO:0004938 biolink:MolecularActivity alpha2-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein. go-plus.json alpha2 adrenoceptor http://purl.obolibrary.org/obo/GO_0004938 GO:0004937 biolink:MolecularActivity alpha1-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein. go-plus.json alpha1 adrenoceptor http://purl.obolibrary.org/obo/GO_0004937 CHEBI:38012 biolink:ChemicalSubstance aminoglycoside sulfate salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_38012 NCBITaxon:6935 biolink:OrganismalEntity Ixodida go-plus.json ticks http://purl.obolibrary.org/obo/NCBITaxon_6935 GO:0004901 biolink:MolecularActivity granulocyte macrophage colony-stimulating factor receptor activity Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json GMC-SF receptor activity|granulocyte macrophage colony stimulating factor receptor activity|GM-CSF receptor activity|CSF2R|CSF-2 receptor activity http://purl.obolibrary.org/obo/GO_0004901 NCBITaxon:6934 biolink:OrganismalEntity Parasitiformes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6934 GO:0004900 biolink:MolecularActivity erythropoietin receptor activity Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004900 NCBITaxon:6933 biolink:OrganismalEntity Acari go-plus.json Acarina|mites & ticks|mites and ticks http://purl.obolibrary.org/obo/NCBITaxon_6933 CHEBI:53628 biolink:ChemicalSubstance 2,6-dideoxy-alpha-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_53628 CHEBI:28666 biolink:ChemicalSubstance leukotriene D4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28666 CHEBI:28663 biolink:ChemicalSubstance galactitol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28663 NCBITaxon:6939 biolink:OrganismalEntity Ixodidae go-plus.json hardbacked ticks|hard ticks|scale ticks http://purl.obolibrary.org/obo/NCBITaxon_6939 CHEBI:28661 biolink:ChemicalSubstance gamma-linolenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28661 CHEBI:28660 biolink:ChemicalSubstance (-)-alpha-pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28660 chebi_ph7_3 GO:0004907 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004907 GO:0004906 biolink:MolecularActivity interferon-gamma receptor activity Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IFN-gamma receptor activity|type II interferon receptor activity|IFNG receptor activity http://purl.obolibrary.org/obo/GO_0004906 GO:0004909 biolink:MolecularActivity interleukin-1, type I, activating receptor activity Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins. go-plus.json interleukin-1 type I receptor activity|IL-1 type I, activating receptor|interleukin-1, type I, activating binding|interleukin-1 activating receptor activity|IL-1 type I, activating binding http://purl.obolibrary.org/obo/GO_0004909 GO:0004908 biolink:MolecularActivity interleukin-1 receptor activity Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. Wikipedia:Interleukin-1_receptor go-plus.json IL-1 receptor activity|IL-1R http://purl.obolibrary.org/obo/GO_0004908 GO:0004903 biolink:MolecularActivity growth hormone receptor activity Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004903 GO:0004902 biolink:MolecularActivity granulocyte colony-stimulating factor receptor activity Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json G-CSF receptor activity|CSF3R|granulocyte colony stimulating factor receptor activity http://purl.obolibrary.org/obo/GO_0004902 GO:0004905 biolink:MolecularActivity type I interferon receptor activity Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families. go-plus.json interferon-delta receptor activity|interferon-alpha/beta receptor activity|interferon-kappa receptor activity|interferon-epsilon receptor activity|interferon-tau receptor activity|interferon-zeta receptor activity|type I IFN receptor activity|interferon-omega receptor activity|interferon-beta receptor activity|interferon-alpha receptor activity http://purl.obolibrary.org/obo/GO_0004905 GO:0004904 biolink:MolecularActivity interferon receptor activity Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IFN receptor activity http://purl.obolibrary.org/obo/GO_0004904 GO:0004910 biolink:MolecularActivity interleukin-1, type II, blocking receptor activity Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors. go-plus.json interleukin-1, type II, blocking binding|IL-1 type II, blocking receptor|IL-1 type II, blocking binding|interleukin-1 blocking receptor activity|interleukin-1 type II receptor activity http://purl.obolibrary.org/obo/GO_0004910 NCBITaxon:6945 biolink:OrganismalEntity Ixodes scapularis go-plus.json black-legged tick|Ixodes dammini|deer tick|blacklegged tick|shoulder tick http://purl.obolibrary.org/obo/NCBITaxon_6945 GO:0004912 biolink:MolecularActivity interleukin-3 receptor activity Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Wikipedia:Interleukin-3_receptor go-plus.json IL-3R|IL-3 receptor activity http://purl.obolibrary.org/obo/GO_0004912 GO:0004911 biolink:MolecularActivity interleukin-2 receptor activity Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-2 receptor activity|IL-2R http://purl.obolibrary.org/obo/GO_0004911 NCBITaxon:6944 biolink:OrganismalEntity Ixodes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_6944 CHEBI:28673 biolink:ChemicalSubstance 3-oxopropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28673 CHEBI:28675 biolink:ChemicalSubstance dextrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28675 GO:0004918 biolink:MolecularActivity interleukin-8 receptor activity Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-8R|IL-8 receptor activity http://purl.obolibrary.org/obo/GO_0004918 GO:0004917 biolink:MolecularActivity interleukin-7 receptor activity Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-7R|IL-7 receptor activity http://purl.obolibrary.org/obo/GO_0004917 GO:0004919 biolink:MolecularActivity interleukin-9 receptor activity Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-9R|IL-9 receptor activity http://purl.obolibrary.org/obo/GO_0004919 GO:0004914 biolink:MolecularActivity interleukin-5 receptor activity Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-5R|IL-5 receptor activity http://purl.obolibrary.org/obo/GO_0004914 GO:0004913 biolink:MolecularActivity interleukin-4 receptor activity Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-4R|IL-4 receptor activity http://purl.obolibrary.org/obo/GO_0004913 GO:0004915 biolink:MolecularActivity interleukin-6 receptor activity Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-6R|gp130|IL-6 receptor activity http://purl.obolibrary.org/obo/GO_0004915 CHEBI:28648 biolink:ChemicalSubstance beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28648 CHEBI:53604 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_53604 chebi_ph7_3 CHEBI:28645 biolink:ChemicalSubstance beta-D-fructofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28645 chebi_ph7_3 CHEBI:28644 biolink:ChemicalSubstance 2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28644 chebi_ph7_3 CHEBI:28647 biolink:ChemicalSubstance 3-O-methylgallic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28647 CHEBI:28646 biolink:ChemicalSubstance ammeline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28646 chebi_ph7_3 CHEBI:28640 biolink:ChemicalSubstance lipoteichoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28640 CHEBI:53609 biolink:ChemicalSubstance O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_53609 CHEBI:53608 biolink:ChemicalSubstance O-(N-acetyl-alpha-D-galactosaminyl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_53608 CHEBI:28659 biolink:ChemicalSubstance phosphorus atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_28659 chebi_ph7_3 CHEBI:28651 biolink:ChemicalSubstance (S)-norlaudanosoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28651 CHEBI:28654 biolink:ChemicalSubstance 3-methyl-2-oxovalerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28654 chebi_ph7_3 NCBITaxon:2720872 biolink:OrganismalEntity Aspergillus subgen. Fumigati go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2720872 NCBITaxon:2720870 biolink:OrganismalEntity Aspergillus subgen. Nidulantes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2720870 CHEBI:28629 biolink:ChemicalSubstance precorrin-8X go-plus.json http://purl.obolibrary.org/obo/CHEBI_28629 CHEBI:28624 biolink:ChemicalSubstance tetrahydrofolyl-poly(glutamic acid) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_28624 CHEBI:28621 biolink:ChemicalSubstance triethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28621 CHEBI:7489 biolink:ChemicalSubstance neamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7489 CHEBI:28638 biolink:ChemicalSubstance isobutyronitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_28638 chebi_ph7_3 CHEBI:28637 biolink:ChemicalSubstance 2',3'-cyclic UMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_28637 CHEBI:28639 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28639 CHEBI:28636 biolink:ChemicalSubstance 3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28636 chebi_ph7_3 CHEBI:28635 biolink:ChemicalSubstance 2-isopropylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28635 CHEBI:28630 biolink:ChemicalSubstance 3-hydroxypyridin-4(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28630 chebi_ph7_3 CHEBI:28632 biolink:ChemicalSubstance (S)-3-hydroxyoctanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28632 CHEBI:28631 biolink:ChemicalSubstance 3-phenylpropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28631 NCBITaxon:2 biolink:OrganismalEntity Bacteria go-plus.json Prokaryotae|Prokaryota|eubacteria|Monera|prokaryotes|Procaryotae|prokaryote|bacteria http://purl.obolibrary.org/obo/NCBITaxon_2 NCBITaxon:1 biolink:OrganismalEntity root go-plus.json all http://purl.obolibrary.org/obo/NCBITaxon_1 GO:0004888 biolink:MolecularActivity transmembrane signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. Reactome:R-HSA-193672 go-plus.json transmembrane signalling receptor activity|transmembrane receptor activity http://purl.obolibrary.org/obo/GO_0004888 GO:0004887 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004887 GO:0004889 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004889 GO:0004884 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004884 GO:0004883 biolink:MolecularActivity glucocorticoid receptor activity Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function. go-plus.json http://purl.obolibrary.org/obo/GO_0004883 GO:0004886 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004886 GO:0004880 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004880 GO:0004882 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004882 CHEBI:133331 biolink:ChemicalSubstance metal oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133331 CHEBI:77575 biolink:ChemicalSubstance alkyl,acyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77575 chebi_ph7_3 CHEBI:77578 biolink:ChemicalSubstance monoalkyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77578 chebi_ph7_3 CHEBI:77576 biolink:ChemicalSubstance monoalkyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77576 chebi_ph7_3 GO:0004899 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004899 GO:0004898 biolink:MolecularActivity obsolete gp130 OBSOLETE. (Was not defined before being made obsolete). go-plus.json gp130 http://purl.obolibrary.org/obo/GO_0004898 GO:0004895 biolink:MolecularActivity cell adhesion receptor activity The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins. go-plus.json http://purl.obolibrary.org/obo/GO_0004895 GO:0004894 biolink:MolecularActivity obsolete T cell receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json T cell receptor activity http://purl.obolibrary.org/obo/GO_0004894 GO:0004897 biolink:MolecularActivity ciliary neurotrophic factor receptor activity Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json gp130|CNTF receptor activity http://purl.obolibrary.org/obo/GO_0004897 GO:0004896 biolink:MolecularActivity cytokine receptor activity Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL receptor|interleukin receptor activity|hematopoietin/interferon-class (D200-domain) cytokine receptor activity http://purl.obolibrary.org/obo/GO_0004896 GO:0004891 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004891 GO:0004890 biolink:MolecularActivity GABA-A receptor activity Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels. go-plus.json ionotropic GABA receptor activity http://purl.obolibrary.org/obo/GO_0004890 GO:0004892 biolink:MolecularActivity obsolete B cell receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json B cell receptor activity http://purl.obolibrary.org/obo/GO_0004892 CHEBI:133345 biolink:ChemicalSubstance 10-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133345 chebi_ph7_3 CHEBI:513 biolink:ChemicalSubstance 1,3,4,6-tetrachlorocyclohexa-1,4-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_513 chebi_ph7_3 CHEBI:133346 biolink:ChemicalSubstance 12-oxo-20-hydroxyleukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133346 chebi_ph7_3 CHEBI:77580 biolink:ChemicalSubstance 1-hexadecyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77580 chebi_ph7_3 CHEBI:77583 biolink:ChemicalSubstance (2S)-2-acetamido-4-aminobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77583 CHEBI:77589 biolink:ChemicalSubstance monoacyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77589 chebi_ph7_3 CHEBI:77587 biolink:ChemicalSubstance (2S)-2-acetamido-4-aminobutanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77587 chebi_ph7_3 GO:0004866 biolink:MolecularActivity endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. go-plus.json endoproteinase inhibitor|proteinase inhibitor|alpha-2 macroglobulin http://purl.obolibrary.org/obo/GO_0004866 GO:0004865 biolink:MolecularActivity protein serine/threonine phosphatase inhibitor activity Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0004865 GO:0004868 biolink:MolecularActivity obsolete serpin OBSOLETE. A superfamily of proteins, many of which inhibit serine proteinases and exhibit a high degree of homology with classical serine proteinase inhibitors such as alpha1-antitrypsin or antithrombin. go-plus.json serpin http://purl.obolibrary.org/obo/GO_0004868 GO:0004867 biolink:MolecularActivity serine-type endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. Reactome:R-HSA-158800|Reactome:R-HSA-158795|Reactome:R-HSA-158893|Reactome:R-HSA-159005|Reactome:R-HSA-159001 go-plus.json serine proteinase inhibitor activity|serine protease inhibitor activity|serpin activity http://purl.obolibrary.org/obo/GO_0004867 GO:0004862 biolink:MolecularActivity cAMP-dependent protein kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase. Reactome:R-HSA-180073 go-plus.json http://purl.obolibrary.org/obo/GO_0004862 GO:0004861 biolink:MolecularActivity cyclin-dependent protein serine/threonine kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase. Reactome:R-HSA-187934|Reactome:R-HSA-69562 go-plus.json cyclin-dependent kinase inhibitor|cyclin-dependent protein kinase inhibitor activity|CDK inhibitor|cyclin dependent protein kinase inhibitor activity|cyclin dependent kinase inhibitor http://purl.obolibrary.org/obo/GO_0004861 GO:0004864 biolink:MolecularActivity protein phosphatase inhibitor activity Binds to and stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins. go-plus.json phosphoprotein phosphatase inhibitor activity|protein phosphatase type 2A inhibitor activity|protein phosphatase 2 inhibitor activity http://purl.obolibrary.org/obo/GO_0004864 GO:0004863 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004863 CHEBI:133318 biolink:ChemicalSubstance hydroxy fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_133318 GO:0004860 biolink:MolecularActivity protein kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0004860 CHEBI:133319 biolink:ChemicalSubstance 10,11-dihydro-12-oxoleukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133319 chebi_ph7_3 CHEBI:77593 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77593 chebi_ph7_3 CHEBI:77592 biolink:ChemicalSubstance monacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77592 chebi_ph7_3 GO:0004869 biolink:MolecularActivity cysteine-type endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. go-plus.json thiol protease inhibitor|cysteine protease inhibitor activity|cystatin http://purl.obolibrary.org/obo/GO_0004869 GO:0004877 biolink:MolecularActivity complement component C3b receptor activity Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004877 GO:0004876 biolink:MolecularActivity complement component C3a receptor activity Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json C3a anaphylatoxin receptor activity http://purl.obolibrary.org/obo/GO_0004876 GO:0004879 biolink:MolecularActivity nuclear receptor activity A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytoplasm, which leads to its tranlocation to the nucleus. go-plus.json calcitriol receptor activity|vitamin A receptor activity|9-cis retinoic acid receptor activity|juvenile hormone receptor activity|ecdysteroid hormone receptor activity|nuclear receptor activity|ligand-dependent nuclear receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|1,25-(OH)2D3 receptor activity|ligand-dependent transcription factor activity|estrogen nuclear receptor activity|thyroid hormone receptor activity|nuclear hormone receptor|RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding|retinoid-X receptor activity|androgen receptor activity|retinoic acid receptor activity|RXR|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding|vitamin D3 receptor activity|RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding|vitamin D receptor activity|glucocorticoid receptor activity http://purl.obolibrary.org/obo/GO_0004879 GO:0004878 biolink:MolecularActivity complement component C5a receptor activity Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json C5a anaphylatoxin receptor activity http://purl.obolibrary.org/obo/GO_0004878 GO:0004873 biolink:MolecularActivity asialoglycoprotein receptor activity Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0004873 goslim_chembl GO:0004872 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004872 GO:0004875 biolink:MolecularActivity complement receptor activity Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json anaphylatoxin receptor activity http://purl.obolibrary.org/obo/GO_0004875 GO:0004874 biolink:MolecularActivity obsolete aryl hydrocarbon receptor activity OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding. go-plus.json http://purl.obolibrary.org/obo/GO_0004874 CL:0011115 biolink:Cell precursor cell A cell that, by division or terminal differentiation, can give rise to other cell types. go-plus.json http://purl.obolibrary.org/obo/CL_0011115 GO:0004871 biolink:MolecularActivity obsolete signal transducer activity OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. go-plus.json hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity|quorum sensing signal generator activity|quorum sensing response regulator activity http://purl.obolibrary.org/obo/GO_0004871 GO:0004870 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004870 CL:0011111 biolink:Cell gonadotropin releasing neuron Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction. go-plus.json GnRH neuron|GnRH-secreting neuron http://purl.obolibrary.org/obo/CL_0011111 CL:0011110 biolink:Cell histaminergic neuron Neuron that secretes histamine. go-plus.json http://purl.obolibrary.org/obo/CL_0011110 GO:0004844 biolink:MolecularActivity uracil DNA N-glycosylase activity Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine. Reactome:R-HSA-110215|Reactome:R-HSA-110217 go-plus.json uracil-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0004844 GO:0004843 biolink:MolecularActivity thiol-dependent deubiquitinase Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein. Reactome:R-HSA-5696564|Reactome:R-HSA-5688797|Reactome:R-HSA-4641236|Reactome:R-HSA-5689972|Reactome:R-HSA-6781779|Reactome:R-HSA-6783177|Reactome:R-HSA-6782106|Reactome:R-HSA-3640872|Reactome:R-HSA-9033491|Reactome:R-HSA-8875443|Reactome:R-HSA-5696872|Reactome:R-HSA-6781764|Reactome:R-HSA-6782820|Reactome:R-HSA-5653770|Reactome:R-HSA-5690152|Reactome:R-HSA-5696465|Reactome:R-HSA-9653514|Reactome:R-HSA-5690159|Reactome:R-HSA-5696947|Reactome:R-HSA-5690759|Reactome:R-HSA-5696945|Reactome:R-HSA-5696997|Reactome:R-HSA-6786171|EC:3.4.19.12|Reactome:R-HSA-6782628|Reactome:R-HSA-5696534|Reactome:R-HSA-5655466|Reactome:R-HSA-3215310|Reactome:R-HSA-5697009|Reactome:R-HSA-1358795|Reactome:R-HSA-8865182|Reactome:R-HSA-5696968|Reactome:R-HSA-8853503|Reactome:R-HSA-3215295|Reactome:R-HSA-6781814|Reactome:R-HSA-8986083|Reactome:R-HSA-5689950|Reactome:R-HSA-5688837|Reactome:R-HSA-8873946|Reactome:R-HSA-5696605|Reactome:R-HSA-6782069|Reactome:R-HSA-5696914|Reactome:R-HSA-5690196|Reactome:R-HSA-5689973|Reactome:R-HSA-2179291|Reactome:R-HSA-5690319|Reactome:R-HSA-5691381|Reactome:R-HSA-5696958|Reactome:R-HSA-8853529|Reactome:R-HSA-6807206|Reactome:R-HSA-9033478|Reactome:R-HSA-8869456|Reactome:R-HSA-8853514|Reactome:R-HSA-5696600|Reactome:R-HSA-5690080|Reactome:R-HSA-5690157|Reactome:R-HSA-5690790|Reactome:R-HSA-8853515|Reactome:R-HSA-870437|Reactome:R-HSA-8862184|Reactome:R-HSA-6781897|Reactome:R-HSA-5696960|Reactome:R-HSA-5696627|Reactome:R-HSA-6807118 go-plus.json deubiquitinase activity|ubiquitin-specific protease activity|UCH2|ubiquitin hydrolase activity|thiol-dependent ubiquitinyl hydrolase activity|deubiquitylase|deubiquitinating enzyme|ubiquitinyl hydrolase activity|deubiquitinase|ubiquitinyl hydrolase 1 activity|UBP|thiol-dependent ubiquitin-specific protease activity|ubiquitin C-terminal hydrolase http://purl.obolibrary.org/obo/GO_0004843 GO:0004846 biolink:MolecularActivity urate oxidase activity Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide. UM-BBD_reactionID:r1322|RHEA:21368|EC:1.7.3.3|MetaCyc:URATE-OXIDASE-RXN go-plus.json uric acid oxidase activity|uricase II activity|uricase activity|urate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004846 GO:0004845 biolink:MolecularActivity uracil phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil. MetaCyc:URACIL-PRIBOSYLTRANS-RXN|KEGG_REACTION:R00966|RHEA:13017|EC:2.4.2.9 go-plus.json UPRTase activity|UMP:pyrophosphate phosphoribosyltransferase activity|UMP:diphosphate phospho-alpha-D-ribosyltransferase activity|UMP pyrophosphorylase activity|UMP diphosphorylase activity|uridine 5'-phosphate pyrophosphorylase activity|uridine monophosphate pyrophosphorylase activity|uridylic pyrophosphorylase activity|uridylate pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0004845 GO:0004840 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004840 GO:0004842 biolink:MolecularActivity ubiquitin-protein transferase activity Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. Reactome:R-HSA-8956106|Reactome:R-HSA-936986|Reactome:R-HSA-983140|Reactome:R-HSA-2737728|Reactome:R-HSA-2730904|Reactome:R-HSA-174057|Reactome:R-HSA-183084|Reactome:R-HSA-400267|Reactome:R-HSA-179417|Reactome:R-HSA-5607728|Reactome:R-HSA-173545|Reactome:R-HSA-5607725|Reactome:R-HSA-5660753|Reactome:R-HSA-5610746|Reactome:R-HSA-5610745|Reactome:R-HSA-2172172|Reactome:R-HSA-168915|Reactome:R-HSA-2213017|Reactome:R-HSA-1169402|Reactome:R-HSA-450358|Reactome:R-HSA-5610742|Reactome:R-HSA-5684250|Reactome:R-HSA-451418|Reactome:R-HSA-3134804|Reactome:R-HSA-5693108|Reactome:R-HSA-5357757|Reactome:R-HSA-1980118|Reactome:R-HSA-918224|Reactome:R-HSA-5362412|Reactome:R-HSA-5205682|Reactome:R-HSA-211734|Reactome:R-HSA-182986|Reactome:R-HSA-174104|Reactome:R-HSA-1980074|Reactome:R-HSA-174144|Reactome:R-HSA-5483238|Reactome:R-HSA-9013974|Reactome:R-HSA-1358790|Reactome:R-HSA-975147|Reactome:R-HSA-9628444|Reactome:R-HSA-5655170|Reactome:R-HSA-5667107|Reactome:R-HSA-264444|Reactome:R-HSA-5652009|Reactome:R-HSA-183051|Reactome:R-HSA-1852623|Reactome:R-HSA-2769007|Reactome:R-HSA-870449|Reactome:R-HSA-3797226|Reactome:R-HSA-3249386|Reactome:R-HSA-2179276|Reactome:R-HSA-183036|Reactome:R-HSA-741386|Reactome:R-HSA-446877|Reactome:R-HSA-202534|Reactome:R-HSA-1169394|Reactome:R-HSA-8948709|Reactome:R-HSA-3781009|Reactome:R-HSA-3788724|Reactome:R-HSA-4332236|Reactome:R-HSA-5668534|KEGG_REACTION:R03876|Reactome:R-HSA-173542|Reactome:R-HSA-2186785|Reactome:R-HSA-174159|Reactome:R-HSA-3000335|Reactome:R-HSA-936412|Reactome:R-HSA-9645414|Reactome:R-HSA-1918095|Reactome:R-HSA-5667111|Reactome:R-HSA-180597|Reactome:R-HSA-1977296|Reactome:R-HSA-1234172|Reactome:R-HSA-1912357|Reactome:R-HSA-1169397|Reactome:R-HSA-2186747|Reactome:R-HSA-174227|Reactome:R-HSA-3134946|Reactome:R-HSA-75824|Reactome:R-HSA-1169395|Reactome:R-HSA-174195|Reactome:R-HSA-5675470|Reactome:R-HSA-983153|Reactome:R-HSA-209063|Reactome:R-HSA-205118|Reactome:R-HSA-69598|Reactome:R-HSA-983156|Reactome:R-HSA-936942|Reactome:R-HSA-202453|Reactome:R-HSA-1918092|Reactome:R-HSA-1912386|Reactome:R-HSA-2169050|Reactome:R-HSA-2187368|Reactome:R-HSA-1169406|Reactome:R-HSA-3780995|Reactome:R-HSA-183089|Reactome:R-HSA-2682349|Reactome:R-HSA-5691108|Reactome:R-HSA-1234163|Reactome:R-HSA-9701000|Reactome:R-HSA-1358792|Reactome:R-HSA-975118|Reactome:R-HSA-5607756|Reactome:R-HSA-1358789|Reactome:R-HSA-180540|Reactome:R-HSA-9645394|Reactome:R-HSA-182993|Reactome:R-HSA-1169398|Reactome:R-HSA-1363331|Reactome:R-HSA-5668454|Reactome:R-HSA-2900765|Reactome:R-HSA-9013069|Reactome:R-HSA-1169405|Reactome:R-HSA-9688831|Reactome:R-HSA-201425|Reactome:R-HSA-5607757|Reactome:R-HSA-9014342|Reactome:R-HSA-1253282|Reactome:R-HSA-187575 go-plus.json ubiquitin protein ligase activity|ubiquitin ligase activity|ubiquitin conjugating enzyme activity|anaphase-promoting complex activity|ubiquitin protein-ligase activity|ubiquitin-conjugating enzyme activity|E3|E2 http://purl.obolibrary.org/obo/GO_0004842 GO:0004841 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004841 CL:0011103 biolink:Cell sympathetic neuron Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. go-plus.json http://purl.obolibrary.org/obo/CL_0011103 CL:0011101 biolink:Cell chorionic trophoblast cell Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. go-plus.json http://purl.obolibrary.org/obo/CL_0011101 CL:0011109 biolink:Cell hypocretin-secreting neuron A neuron that releases hypocretin as a neurotransmitter. go-plus.json orexin http://purl.obolibrary.org/obo/CL_0011109 CL:0011108 biolink:Cell colon epithelial cell Epithelial cell that is part of the colon epithelium. go-plus.json colonic epithelial cell http://purl.obolibrary.org/obo/CL_0011108 GO:0004848 biolink:MolecularActivity ureidoglycolate hydrolase activity Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+). EC:3.5.3.19|KEGG_REACTION:R00469|RHEA:19809|MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN go-plus.json (S)-ureidoglycolate amidohydrolase (decarboxylating) http://purl.obolibrary.org/obo/GO_0004848 GO:0004847 biolink:MolecularActivity urea carboxylase activity Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate. RHEA:20896|KEGG_REACTION:R00774|EC:6.3.4.6|MetaCyc:UREA-CARBOXYLASE-RXN go-plus.json urea carboxylase (hydrolyzing) activity|urease (ATP-hydrolysing)|urea:carbon-dioxide ligase (ADP-forming)|UCA activity|UALase activity|urea amidolyase activity|urease (ATP-hydrolyzing) activity|ATP--urea amidolyase activity|urea carboxylase (hydrolysing) http://purl.obolibrary.org/obo/GO_0004847 GO:0004849 biolink:MolecularActivity uridine kinase activity Catalysis of the reaction: ATP + uridine = ADP + UMP. MetaCyc:URIDINEKIN-RXN|Reactome:R-HSA-8954327|EC:2.7.1.48|RHEA:16825 go-plus.json ATP:uridine 5'-phosphotransferase activity|uridine-cytidine kinase activity|uridine kinase reaction|uridine monophosphokinase activity|pyrimidine ribonucleoside kinase activity|uridine phosphokinase activity|uridine kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0004849 GO:0004855 biolink:MolecularActivity xanthine oxidase activity Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide. RHEA:21132|EC:1.17.3.2|MetaCyc:XANTHINE-OXIDASE-RXN|Reactome:R-HSA-74247|UM-BBD_enzymeID:e0781|Reactome:R-HSA-74258 go-plus.json xanthine:xanthine oxidase activity|Schardinger enzyme activity|xanthine:O(2) oxidoreductase activity|xanthine oxidoreductase activity|hypoxanthine-xanthine oxidase activity|xanthine:O2 oxidoreductase activity|xanthine:oxygen oxidoreductase activity|schardinger enzyme http://purl.obolibrary.org/obo/GO_0004855 GO:0004854 biolink:MolecularActivity xanthine dehydrogenase activity Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+. RHEA:16669|EC:1.17.1.4|MetaCyc:RXN0-901 go-plus.json xanthine:NAD+ oxidoreductase activity|xanthine-NAD oxidoreductase activity|xanthine/NAD+ oxidoreductase activity|xanthine oxidoreductase activity|NAD-xanthine dehydrogenase activity|xanthine/NAD(+) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004854 GO:0004857 biolink:MolecularActivity enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme. go-plus.json metalloenzyme inhibitor activity http://purl.obolibrary.org/obo/GO_0004857 GO:0004856 biolink:MolecularActivity xylulokinase activity Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+). MetaCyc:XYLULOKIN-RXN|Reactome:R-HSA-5662466|KEGG_REACTION:R01639|EC:2.7.1.17|RHEA:10964 go-plus.json ATP:D-xylulose 5-phosphotransferase activity|xylulose kinase activity|xylulokinase (phosphorylating)|D-xylulokinase activity http://purl.obolibrary.org/obo/GO_0004856 GO:0004851 biolink:MolecularActivity uroporphyrin-III C-methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2. MetaCyc:UROPORIIIMETHYLTRANSA-RXN|EC:2.1.1.107|RHEA:32459 go-plus.json SirA|S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity|adenosylmethionine-uroporphyrinogen III methyltransferase activity|uroporphyrinogen-III C-methyltransferase activity|uroporphyrinogen III methylase activity|S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity|S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity|urogen III methylase activity|uroporphyrinogen-III methyltransferase activity|uroporphyrinogen methyltransferase activity|CobA|CysG|uroporphyrinogen-III methylase activity|SUMT activity http://purl.obolibrary.org/obo/GO_0004851 NCBITaxon:51291 biolink:OrganismalEntity Chlamydiales go-plus.json chlamydias http://purl.obolibrary.org/obo/NCBITaxon_51291 GO:0004850 biolink:MolecularActivity uridine phosphorylase activity Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate. RHEA:24388|MetaCyc:URPHOS-RXN|EC:2.4.2.3|Reactome:R-HSA-74372|Reactome:R-HSA-74376 go-plus.json uridine:phosphate alpha-D-ribosyltransferase activity|UPase activity|UPH|pyrimidine phosphorylase activity|UrdPase activity http://purl.obolibrary.org/obo/GO_0004850 GO:0004853 biolink:MolecularActivity uroporphyrinogen decarboxylase activity Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2. RHEA:19865|MetaCyc:UROGENDECARBOX-RXN|Reactome:R-HSA-190182|Reactome:R-HSA-189425|EC:4.1.1.37 go-plus.json porphyrinogen carboxy-lyase activity|uroporphyrinogen III decarboxylase activity|uroporphyrinogen-III carboxy-lyase activity|porphyrinogen decarboxylase activity|uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming) http://purl.obolibrary.org/obo/GO_0004853 GO:0004852 biolink:MolecularActivity uroporphyrinogen-III synthase activity Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III. MetaCyc:UROGENIIISYN-RXN|Reactome:R-HSA-189488|RHEA:18965|KEGG_REACTION:R03165|EC:4.2.1.75 go-plus.json uroporphyrinogen III cosynthase activity|hydroxymethylbilane hydro-lyase (cyclizing) activity|porphobilinogenase activity|hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)|uroporphyrinogen-III cosynthase activity|URO-synthase activity|uroporphyrinogen isomerase activity|uroporphyrinogen-III cosynthetase activity http://purl.obolibrary.org/obo/GO_0004852 CHEBI:133309 biolink:ChemicalSubstance 12-dehydro-leukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133309 chebi_ph7_3 CHEBI:133301 biolink:ChemicalSubstance O-{S-[19-(4-hydroxyphenyl)nonadecanoyl]pantetheine-4'-phosphoryl}serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133301 chebi_ph7_3 CHEBI:133300 biolink:ChemicalSubstance O-{S-[17-(4-hydroxyphenyl)heptadecanoyl]pantetheine-4'-phosphoryl}serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133300 chebi_ph7_3 CHEBI:133304 biolink:ChemicalSubstance S-anthraniloyl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133304 chebi_ph7_3 GO:0004859 biolink:MolecularActivity phospholipase inhibitor activity Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0004859 GO:0004858 biolink:MolecularActivity dUTP pyrophosphatase inhibitor activity Binds to and stops, prevents or reduces the activity of dUTP pyrophosphatase. go-plus.json http://purl.obolibrary.org/obo/GO_0004858 GO:0004822 biolink:MolecularActivity isoleucine-tRNA ligase activity Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+). MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380176|KEGG_REACTION:R03656|Reactome:R-HSA-379893|EC:6.1.1.5|RHEA:11060 go-plus.json L-isoleucine:tRNAIle ligase (AMP-forming)|isoleucine-tRNA synthetase activity|isoleucyl-transfer ribonucleate synthetase activity|isoleucine-transfer RNA ligase activity|isoleucine translase activity|isoleucyl-transfer RNA synthetase activity|isoleucyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004822 GO:0004821 biolink:MolecularActivity histidine-tRNA ligase activity Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). Reactome:R-HSA-380234|Reactome:R-HSA-379844|MetaCyc:HISTIDINE--TRNA-LIGASE-RXN|EC:6.1.1.21|RHEA:17313 go-plus.json histidyl-transfer ribonucleate synthetase activity|histidine translase activity|L-histidine:tRNAHis ligase (AMP-forming)|histidyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004821 GO:0004824 biolink:MolecularActivity lysine-tRNA ligase activity Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). Reactome:R-HSA-380008|Reactome:R-HSA-380233|MetaCyc:LYSINE--TRNA-LIGASE-RXN|RHEA:20792|EC:6.1.1.6 go-plus.json L-lysine:tRNALys ligase (AMP-forming)|lysine-tRNA synthetase activity|lysyl-transfer RNA synthetase activity|lysyl-transfer ribonucleate synthetase activity|L-lysine-transfer RNA ligase activity|lysyl-tRNA synthetase activity|lysine translase activity http://purl.obolibrary.org/obo/GO_0004824 GO:0004823 biolink:MolecularActivity leucine-tRNA ligase activity Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu). Reactome:R-HSA-380200|Reactome:R-HSA-379974|MetaCyc:LEUCINE--TRNA-LIGASE-RXN|KEGG_REACTION:R03657|RHEA:11688|EC:6.1.1.4 go-plus.json L-leucine:tRNALeu ligase (AMP-forming)|leucyl-transfer ribonucleic acid synthetase activity|leucine-tRNA synthetase activity|leucyl-transfer ribonucleate synthetase activity|leucyl-transfer RNA synthetase activity|leucine translase activity|leucyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004823 GO:0004820 biolink:MolecularActivity glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). Reactome:R-HSA-380240|EC:6.1.1.14|RHEA:16013|Reactome:R-HSA-380048|MetaCyc:GLYCINE--TRNA-LIGASE-RXN go-plus.json glycine:tRNAGly ligase (AMP-forming) activity|glycyl-transfer ribonucleic acid synthetase activity|glycyl-transfer RNA synthetase activity|glycyl translase activity|glycyl-transfer ribonucleate synthetase activity|glycyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004820 CHEBI:28586 biolink:ChemicalSubstance verbascose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28586 chebi_ph7_3 CHEBI:28585 biolink:ChemicalSubstance 4-carboxy-4'-sulfoazobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28585 CHEBI:28587 biolink:ChemicalSubstance D-threose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28587 chebi_ph7_3 CHEBI:28581 biolink:ChemicalSubstance UDP-N-acetyl-D-mannosaminouronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28581 CHEBI:28591 biolink:ChemicalSubstance guaiacol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28591 chebi_ph7_3 GO:0004829 biolink:MolecularActivity threonine-tRNA ligase activity Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr). Reactome:R-HSA-380201|Reactome:R-HSA-380002|MetaCyc:THREONINE--TRNA-LIGASE-RXN|RHEA:24624|EC:6.1.1.3 go-plus.json threonyl-transfer ribonucleic acid synthetase activity|L-threonine:tRNAThr ligase (AMP-forming)|TRS|threonyl-transfer RNA synthetase activity|threonyl ribonucleic synthetase activity|threonine-transfer ribonucleate synthetase activity|threonyl-transfer ribonucleate synthetase activity|threonine translase activity|threonyl-tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004829 GO:0004826 biolink:MolecularActivity phenylalanine-tRNA ligase activity Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380203|Reactome:R-HSA-379848|EC:6.1.1.20|RHEA:19413 go-plus.json L-phenylalanine:tRNAPhe ligase (AMP-forming) activity|phenylalanine-tRNA synthetase activity|phenylalanyl-transfer ribonucleate synthetase activity|phenylalanine translase activity|phenylalanyl-transfer RNA synthetase activity|phenylalanyl-tRNA ligase activity|L-phenylalanyl-tRNA synthetase activity|phenylalanyl-tRNA synthetase activity|phenylalanyl-transfer RNA ligase activity http://purl.obolibrary.org/obo/GO_0004826 GO:0004825 biolink:MolecularActivity methionine-tRNA ligase activity Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met). EC:6.1.1.10|Reactome:R-HSA-380157|MetaCyc:METHIONINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379994|RHEA:13481 go-plus.json methionyl-transfer ribonucleate synthetase activity|methionine translase activity|methionyl-tRNA synthetase activity|methionyl-transfer RNA synthetase activity|MetRS activity|methionyl-transfer ribonucleic acid synthetase activity|L-methionine:tRNAMet ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0004825 GO:0004828 biolink:MolecularActivity serine-tRNA ligase activity Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). RHEA:12292|Reactome:R-HSA-379992|EC:6.1.1.11|MetaCyc:SERINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380239 go-plus.json seryl-transfer ribonucleate synthetase activity|serine translase activity|seryl-transfer ribonucleic acid synthetase activity|seryl-tRNA synthetase activity|seryl-transfer RNA synthetase activity|L-serine:tRNASer ligase (AMP-forming)|SerRS activity http://purl.obolibrary.org/obo/GO_0004828 GO:0004827 biolink:MolecularActivity proline-tRNA ligase activity Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). Reactome:R-HSA-380198|Reactome:R-HSA-379865|EC:6.1.1.15|MetaCyc:PROLINE--TRNA-LIGASE-RXN|RHEA:14305 go-plus.json prolyl-transferRNA synthetase activity|L-proline:tRNAPro ligase (AMP-forming)|prolyl-transfer ribonucleate synthetase activity|proline translase activity|prolyl-tRNA synthetase activity|prolyl-s-RNA synthetase activity|prolyl-transfer ribonucleic acid synthetase activity|prolinyl-tRNA ligase activity http://purl.obolibrary.org/obo/GO_0004827 GO:0004833 biolink:MolecularActivity tryptophan 2,3-dioxygenase activity Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine. RHEA:24536|MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN|Reactome:R-HSA-71188|Reactome:R-HSA-198563|Reactome:R-HSA-888614|EC:1.13.11.11 go-plus.json TDO|L-tryptophan 2,3-dioxygenase activity|indolamine 2,3-dioxygenase activity|tryptophan peroxidase activity|L-tryptophan pyrrolase activity|tryptophan pyrrolase activity|indoleamine-pyrrole 2,3-dioxygenase activity|tryptamin 2,3-dioxygenase activity|L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|tryptophan oxygenase activity|tryptamine 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0004833 GO:0004832 biolink:MolecularActivity valine-tRNA ligase activity Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+). MetaCyc:VALINE--TRNA-LIGASE-RXN|KEGG_REACTION:R03665|EC:6.1.1.9|Reactome:R-HSA-380199|Reactome:R-HSA-380042|RHEA:10704 go-plus.json valyl-tRNA synthetase activity|L-valine:tRNAVal ligase (AMP-forming)|valyl-transfer ribonucleate synthetase activity|valine translase activity|valine transfer ribonucleate ligase activity|valyl-transfer ribonucleic acid synthetase activity|valyl-transfer RNA synthetase activity http://purl.obolibrary.org/obo/GO_0004832 GO:0004835 biolink:MolecularActivity tubulin-tyrosine ligase activity Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate. EC:6.3.2.25|RHEA:17605|Reactome:R-HSA-8955706|MetaCyc:6.3.2.25-RXN go-plus.json tubulinyl-tyrosine ligase activity|TTL activity|alpha-tubulin:L-tyrosine ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0004835 GO:0004834 biolink:MolecularActivity tryptophan synthase activity Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. KEGG_REACTION:R02722|EC:4.2.1.20|RHEA:10532|MetaCyc:TRYPSYN-RXN go-plus.json indoleglycerol phosphate aldolase activity|L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]|L-serine hydro-lyase (adding indoleglycerol-phosphate)|tryptophan desmolase activity|L-tryptophan synthetase activity|tryptophan synthetase activity http://purl.obolibrary.org/obo/GO_0004834 GO:0004831 biolink:MolecularActivity tyrosine-tRNA ligase activity Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+). RHEA:10220|EC:6.1.1.1|MetaCyc:TYROSINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380170|KEGG_REACTION:R02918|Reactome:R-HSA-379980 go-plus.json L-tyrosine-tRNATyr ligase (AMP-forming)|tyrosyl-transfer ribonucleic acid synthetase activity|L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity|tyrosyl-transfer RNA synthetase activity|tyrosyl-tRNA ligase activity|tyrosine-transfer ribonucleate synthetase activity|tyrosyl-tRNA synthetase activity|tyrosyl-transfer ribonucleate synthetase activity|tyrosine-transfer RNA ligase activity|L-tyrosine:tRNATyr ligase (AMP-forming)|tyrosine translase activity|tyrosine tRNA synthetase activity http://purl.obolibrary.org/obo/GO_0004831 GO:0004830 biolink:MolecularActivity tryptophan-tRNA ligase activity Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp). Reactome:R-HSA-380222|EC:6.1.1.2|Reactome:R-HSA-379977|RHEA:24080|MetaCyc:TRYPTOPHAN--TRNA-LIGASE-RXN go-plus.json tryptophanyl-transfer ribonucleic synthetase activity|L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity|tryptophanyl-transfer RNA synthetase activity|TrpRS activity|L-tryptophan-tRNATrp ligase (AMP-forming)|tryptophanyl ribonucleic synthetase activity|tryptophanyl-transfer ribonucleate synthetase activity|tryptophanyl-tRNA synthetase activity|tryptophanyl-tRNA synthase activity|tryptophan translase activity|tryptophanyl-transfer ribonucleic acid synthetase activity|L-tryptophan:tRNATrp ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0004830 CHEBI:28599 biolink:ChemicalSubstance siroheme go-plus.json http://purl.obolibrary.org/obo/CHEBI_28599 CHEBI:28592 biolink:ChemicalSubstance ricinoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28592 GO:0004837 biolink:MolecularActivity tyrosine decarboxylase activity Catalysis of the reaction: L-tyrosine = tyramine + CO2. RHEA:14345|MetaCyc:TYROSINE-DECARBOXYLASE-RXN|EC:4.1.1.25 go-plus.json L-tyrosine decarboxylase activity|L-tyrosine carboxy-lyase activity|L-(-)-tyrosine apodecarboxylase activity|L-tyrosine carboxy-lyase (tyramine-forming) http://purl.obolibrary.org/obo/GO_0004837 GO:0004836 biolink:MolecularActivity tyramine-beta hydroxylase activity Catalysis of the hydroxylation of tyramine to form octopamine. go-plus.json http://purl.obolibrary.org/obo/GO_0004836 GO:0004839 biolink:MolecularActivity ubiquitin activating enzyme activity Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. EC:6.2.1.45|Reactome:R-HSA-8865090|Reactome:R-HSA-8852132|Reactome:R-HSA-8865050|Reactome:R-HSA-8852134|Reactome:R-HSA-8852133|Reactome:R-HSA-8865098 go-plus.json E1 ubiquitin-activating enzyme http://purl.obolibrary.org/obo/GO_0004839 GO:0004838 biolink:MolecularActivity L-tyrosine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate. MetaCyc:TYROSINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-517444|EC:2.6.1.5|RHEA:15093|Reactome:R-HSA-71155 go-plus.json L-tyrosine aminotransferase activity|tyrosine-2-ketoglutarate aminotransferase activity|tyrosine-alpha-ketoglutarate transaminase activity|phenylalanine transaminase activity|tyrosine aminotransferase activity|L-phenylalanine 2-oxoglutarate aminotransferase activity|phenylpyruvic acid transaminase activity|glutamic phenylpyruvic aminotransferase activity|tyrosine transaminase activity|tyrosine-alpha-ketoglutarate aminotransferase activity|phenylalanine aminotransferase activity|glutamic-hydroxyphenylpyruvic transaminase activity|phenylalanine-alpha-ketoglutarate transaminase activity|phenylpyruvate transaminase activity|TyrAT activity http://purl.obolibrary.org/obo/GO_0004838 CHEBI:77506 biolink:ChemicalSubstance 1-pentadecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_77506 chebi_ph7_3 CHEBI:77503 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77503 CHEBI:77500 biolink:ChemicalSubstance (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77500 CHEBI:133398 biolink:ChemicalSubstance L-methionyl-L-alanyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133398 chebi_ph7_3 CHEBI:133399 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-alanyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133399 chebi_ph7_3 CHEBI:133392 biolink:ChemicalSubstance prostaglandin C2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133392 chebi_ph7_3 CHEBI:133391 biolink:ChemicalSubstance prostaglandin B2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133391 chebi_ph7_3 CHEBI:133393 biolink:ChemicalSubstance prostaglandin B1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133393 chebi_ph7_3 CHEBI:133396 biolink:ChemicalSubstance prostaglandin J2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133396 chebi_ph7_3 CHEBI:77528 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z)-hexacosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77528 CHEBI:77527 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77527 CHEBI:77526 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z)-tetracosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77526 CHEBI:77525 biolink:ChemicalSubstance (17Z)-hexacosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77525 CHEBI:77524 biolink:ChemicalSubstance hexadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77524 CHEBI:77523 biolink:ChemicalSubstance Maillard reaction product go-plus.json http://purl.obolibrary.org/obo/CHEBI_77523 CHEBI:77522 biolink:ChemicalSubstance (9Z,12Z)-hexadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77522 CHEBI:77521 biolink:ChemicalSubstance thermal degradation product go-plus.json http://purl.obolibrary.org/obo/CHEBI_77521 CHEBI:77539 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z)-octatriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77539 CHEBI:77538 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z)-hexatriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77538 CHEBI:77537 biolink:ChemicalSubstance trans-9-octadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77537 chebi_ph7_3 CHEBI:77536 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z)-tetratriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77536 CHEBI:133375 biolink:ChemicalSubstance N-acetyl-L-threonyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133375 chebi_ph7_3 CHEBI:133378 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-leucyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133378 chebi_ph7_3 CHEBI:133377 biolink:ChemicalSubstance L-methionyl-L-leucyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133377 chebi_ph7_3 CHEBI:133379 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-isoleucyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133379 chebi_ph7_3 CHEBI:133370 biolink:ChemicalSubstance prostaglandin A2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133370 chebi_ph7_3 CHEBI:133372 biolink:ChemicalSubstance N-acetyl-L-cysteinyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133372 chebi_ph7_3 CHEBI:77535 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z)-dotriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77535 CHEBI:133371 biolink:ChemicalSubstance N-acetyl-L-valyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133371 chebi_ph7_3 CHEBI:77534 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z)-triacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77534 CHEBI:133374 biolink:ChemicalSubstance 13,14-dihydro-15-keto-PGF2alpha(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133374 chebi_ph7_3 CHEBI:77532 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z)-octacosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77532 CHEBI:77549 biolink:ChemicalSubstance (2E,9Z)-hexadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77549 chebi_ph7_3 CHEBI:77548 biolink:ChemicalSubstance trans-2-undecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77548 chebi_ph7_3 CHEBI:77547 biolink:ChemicalSubstance undecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77547 chebi_ph7_3 GO:0038203 biolink:BiologicalProcess TORC2 signaling A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. go-plus.json TORC2 signal transduction http://purl.obolibrary.org/obo/GO_0038203 CHEBI:133387 biolink:ChemicalSubstance L-methionyl-L-tryptophyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133387 chebi_ph7_3 GO:0038202 biolink:BiologicalProcess TORC1 signaling A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. go-plus.json TORC1 signal transduction http://purl.obolibrary.org/obo/GO_0038202 CHEBI:133386 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-tryptophyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133386 chebi_ph7_3 CHEBI:133381 biolink:ChemicalSubstance 9,10-epoxy-18-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133381 CHEBI:133380 biolink:ChemicalSubstance L-methionyl-L-isoleucyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133380 chebi_ph7_3 CHEBI:133383 biolink:ChemicalSubstance L-methionyl-L-phenylalanyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133383 chebi_ph7_3 CHEBI:77545 biolink:ChemicalSubstance trans-2-pentadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77545 chebi_ph7_3 CHEBI:133382 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-phenylalanyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133382 chebi_ph7_3 GO:0038201 biolink:CellularComponent TOR complex A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K. go-plus.json target of rapamycin complex|mTOR complex|TOR signaling complex http://purl.obolibrary.org/obo/GO_0038201 CHEBI:133385 biolink:ChemicalSubstance L-methionyl-L-tyrosyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133385 chebi_ph7_3 GO:0038200 biolink:MolecularActivity ethylene receptor histidine kinase activity Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0038200 CHEBI:133384 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-tyrosyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133384 chebi_ph7_3 CHEBI:77559 biolink:ChemicalSubstance (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77559 chebi_ph7_3 CHEBI:77558 biolink:ChemicalSubstance (2E,9Z,12Z)-octadecatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77558 chebi_ph7_3 NCBITaxon:135621 biolink:OrganismalEntity Pseudomonadaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_135621 NCBITaxon:135625 biolink:OrganismalEntity Pasteurellales go-plus.json Pasteruellaceae group http://purl.obolibrary.org/obo/NCBITaxon_135625 NCBITaxon:135623 biolink:OrganismalEntity Vibrionales go-plus.json 'Vibrionales'|Vibrionaceae group http://purl.obolibrary.org/obo/NCBITaxon_135623 NCBITaxon:135622 biolink:OrganismalEntity Alteromonadales go-plus.json Alteromonadaceae group http://purl.obolibrary.org/obo/NCBITaxon_135622 CHEBI:133356 biolink:ChemicalSubstance L-methionyl-L-asparaginyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133356 chebi_ph7_3 CHEBI:133358 biolink:ChemicalSubstance N(alpha)-acetyl-L-methionyl-L-asparaginyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133358 chebi_ph7_3 NCBITaxon:99287 biolink:OrganismalEntity Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 go-plus.json Salmonella enterica subsp. enterica serovar Typhimurium LT2|Salmonella enterica subsp. enterica serovar Typhimurium strain LT2|Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2|Salmonella typhimurium LT2 http://purl.obolibrary.org/obo/NCBITaxon_99287 CHEBI:133359 biolink:ChemicalSubstance L-methionyl-L-glutamyl zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133359 chebi_ph7_3 CHEBI:77553 biolink:ChemicalSubstance (2E,9Z)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77553 chebi_ph7_3 CHEBI:77552 biolink:ChemicalSubstance (2E,9E)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77552 chebi_ph7_3 CHEBI:77551 biolink:ChemicalSubstance trans-2-heptadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77551 chebi_ph7_3 CHEBI:77550 biolink:ChemicalSubstance (2R)-pristanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77550 CHEBI:77557 biolink:ChemicalSubstance (2S)-2-methylpentadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_77557 CHEBI:133351 biolink:ChemicalSubstance N-carbamoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_133351 NCBITaxon:135614 biolink:OrganismalEntity Xanthomonadales go-plus.json Lysobacterales http://purl.obolibrary.org/obo/NCBITaxon_135614 CHEBI:133367 biolink:ChemicalSubstance resolvin D2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133367 chebi_ph7_3 CHEBI:133369 biolink:ChemicalSubstance N-acetylglycyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133369 chebi_ph7_3 CHEBI:77560 biolink:ChemicalSubstance 1,1'-dioleyl 2,2'-dilysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77560 CHEBI:77561 biolink:ChemicalSubstance trioleoyl 2-monolysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77561 CHEBI:133361 biolink:ChemicalSubstance L-methionyl-L-glutaminyl(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133361 chebi_ph7_3 CHEBI:133360 biolink:ChemicalSubstance N(alpha)-acetyl-L-methionyl-L-glutamyl(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133360 chebi_ph7_3 CHEBI:133362 biolink:ChemicalSubstance N-acetyl-L-methionyl-L-glutaminyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133362 chebi_ph7_3 GO:1903189 biolink:BiologicalProcess glyoxal metabolic process The chemical reactions and pathways involving glyoxal. go-plus.json glyoxal metabolism http://purl.obolibrary.org/obo/GO_1903189 GO:1903199 biolink:BiologicalProcess negative regulation of L-dopa decarboxylase activity Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity. go-plus.json negative regulation of DOPA decarboxylase activity|down-regulation of DOPA decarboxylase activity|down-regulation of L-dopa decarboxylase activity|down-regulation of DDC activity|down-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|negative regulation of DDC activity|negative regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|inhibition of DOPA decarboxylase activity|inhibition of L-dopa decarboxylase activity|inhibition of 4-dihydroxyl-L-phenylalanine decarboxylase activity|downregulation of DDC activity|down regulation of DDC activity|inhibition of DDC activity|down regulation of DOPA decarboxylase activity|down regulation of L-dopa decarboxylase activity|down regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|downregulation of DOPA decarboxylase activity|downregulation of L-dopa decarboxylase activity|downregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity http://purl.obolibrary.org/obo/GO_1903199 GO:1903198 biolink:BiologicalProcess regulation of L-dopa decarboxylase activity Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity. go-plus.json regulation of DDC activity|regulation of DOPA decarboxylase activity|regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity http://purl.obolibrary.org/obo/GO_1903198 GO:1903197 biolink:BiologicalProcess positive regulation of L-dopa biosynthetic process Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process. go-plus.json positive regulation of L-dopa anabolism|up regulation of L-dopa anabolism|positive regulation of L-dopa synthesis|up-regulation of L-dopa biosynthetic process|up-regulation of L-dopa biosynthesis|up regulation of L-dopa synthesis|positive regulation of L-dopa formation|up regulation of L-dopa formation|upregulation of L-dopa anabolism|upregulation of L-dopa biosynthetic process|upregulation of L-dopa biosynthesis|upregulation of L-dopa synthesis|upregulation of L-dopa formation|up-regulation of L-dopa anabolism|activation of L-dopa anabolism|up regulation of L-dopa biosynthesis|up regulation of L-dopa biosynthetic process|activation of L-dopa biosynthesis|up-regulation of L-dopa synthesis|activation of L-dopa biosynthetic process|activation of L-dopa synthesis|positive regulation of L-dopa biosynthesis|up-regulation of L-dopa formation|activation of L-dopa formation http://purl.obolibrary.org/obo/GO_1903197 GO:1903196 biolink:BiologicalProcess negative regulation of L-dopa biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process. go-plus.json negative regulation of L-dopa synthesis|down-regulation of L-dopa synthesis|negative regulation of L-dopa formation|down-regulation of L-dopa formation|downregulation of L-dopa anabolism|inhibition of L-dopa biosynthetic process|inhibition of L-dopa biosynthesis|downregulation of L-dopa synthesis|down regulation of L-dopa anabolism|inhibition of L-dopa anabolism|downregulation of L-dopa formation|down regulation of L-dopa synthesis|inhibition of L-dopa synthesis|down regulation of L-dopa formation|down regulation of L-dopa biosynthetic process|down regulation of L-dopa biosynthesis|inhibition of L-dopa formation|downregulation of L-dopa biosynthetic process|downregulation of L-dopa biosynthesis|negative regulation of L-dopa anabolism|down-regulation of L-dopa anabolism|negative regulation of L-dopa biosynthesis|down-regulation of L-dopa biosynthesis|down-regulation of L-dopa biosynthetic process http://purl.obolibrary.org/obo/GO_1903196 GO:1903195 biolink:BiologicalProcess regulation of L-dopa biosynthetic process Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process. go-plus.json regulation of L-dopa anabolism|regulation of L-dopa synthesis|regulation of L-dopa formation|regulation of L-dopa biosynthesis http://purl.obolibrary.org/obo/GO_1903195 GO:1903193 biolink:BiologicalProcess sesquarterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquarterpene. go-plus.json sesquarterpene synthesis|sesquarterpene formation|sesquarterpene biosynthesis|sesquarterpene anabolism http://purl.obolibrary.org/obo/GO_1903193 GO:1903192 biolink:BiologicalProcess sesquarterpene metabolic process The chemical reactions and pathways involving sesquarterpene. go-plus.json sesquarterpene metabolism http://purl.obolibrary.org/obo/GO_1903192 GO:1903191 biolink:BiologicalProcess glyoxal biosynthetic process The chemical reactions and pathways resulting in the formation of glyoxal. go-plus.json glyoxal biosynthesis|glyoxal anabolism|glyoxal synthesis|glyoxal formation http://purl.obolibrary.org/obo/GO_1903191 GO:1903190 biolink:BiologicalProcess glyoxal catabolic process The chemical reactions and pathways resulting in the breakdown of glyoxal. go-plus.json glyoxal breakdown|glyoxal catabolism|glyoxal degradation http://purl.obolibrary.org/obo/GO_1903190 UBERON:0035764 biolink:AnatomicalEntity pulmonary lymph node go-plus.json intrapulmonary lymph node|pulmonary node http://purl.obolibrary.org/obo/UBERON_0035764 UBERON:0035763 biolink:AnatomicalEntity cavity of cardiac chamber go-plus.json cardiac chamber cavity|heart lumen|heart cavity http://purl.obolibrary.org/obo/UBERON_0035763 UBERON:0035767 biolink:AnatomicalEntity intrapulmonary bronchus go-plus.json http://purl.obolibrary.org/obo/UBERON_0035767 NCBITaxon:184922 biolink:OrganismalEntity Giardia lamblia ATCC 50803 go-plus.json Giardia intestinalis ATCC 50803 http://purl.obolibrary.org/obo/NCBITaxon_184922 UBERON:0035784 biolink:AnatomicalEntity seminal clot A portion of semen in a coagulated state. go-plus.json seminal coagulum http://purl.obolibrary.org/obo/UBERON_0035784 CHEBI:691622 biolink:ChemicalSubstance 1,3,7-trimethyluric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_691622 chebi_ph7_3 GO:1903109 biolink:BiologicalProcess positive regulation of mitochondrial transcription Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion. go-plus.json upregulation of mitochondrial transcription|up-regulation of transcription from mitochondrial promoter|up regulation of mitochondrial transcription|activation of mitochondrial transcription|positive regulation of transcription from mitochondrial promoter|positive regulation of mitochondrial transcription|upregulation of transcription from mitochondrial promoter|up-regulation of mitochondrial transcription|up regulation of transcription from mitochondrial promoter|activation of transcription from mitochondrial promoter http://purl.obolibrary.org/obo/GO_1903109 GO:1903108 biolink:BiologicalProcess regulation of mitochondrial transcription Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion. go-plus.json regulation of transcription from mitochondrial promoter|regulation of mitochondrial transcription http://purl.obolibrary.org/obo/GO_1903108 GO:1903107 biolink:BiologicalProcess insulin receptor signaling pathway involved in dauer larval development Any insulin receptor signaling pathway that is involved in dauer larval development. go-plus.json daf-2 receptor signaling pathway involved in dauer larval development|insulin receptor signalling pathway involved in dauer larval development http://purl.obolibrary.org/obo/GO_1903107 CHEBI:28563 biolink:ChemicalSubstance beta-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28563 chebi_ph7_3 GO:1903106 biolink:BiologicalProcess positive regulation of insulin receptor signaling pathway involved in determination of adult lifespan Any process that activates or increases the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan. go-plus.json activation of insulin receptor signaling pathway involved in determination of adult lifespan|upregulation of insulin receptor signaling pathway of determination of adult lifespan|up regulation of daf-2 receptor signaling pathway of determination of adult lifespan|positive regulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signalling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway involved in determination of adult lifespan|activation of daf-2 receptor signaling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway of determination of adult lifespan|activation of insulin receptor signaling pathway of determination of adult lifespan|positive regulation of insulin receptor signaling pathway of determination of adult lifespan|up-regulation of insulin receptor signalling pathway of determination of adult lifespan|activation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signaling pathway involved in determination of adult lifespan|upregulation of daf-2 receptor signaling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway of determination of adult lifespan|positive regulation of insulin receptor signalling pathway of determination of adult lifespan|up regulation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway involved in determination of adult lifespan http://purl.obolibrary.org/obo/GO_1903106 GO:1903105 biolink:BiologicalProcess negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan. go-plus.json downregulation of insulin receptor signalling pathway of determination of adult lifespan|downregulation of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signaling pathway involved in determination of adult lifespan|down regulation of insulin receptor signalling pathway of determination of adult lifespan|down regulation of insulin receptor signaling pathway of determination of adult lifespan|inhibition of insulin receptor signalling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway of determination of adult lifespan|down-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|negative regulation of daf-2 receptor signaling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway involved in determination of adult lifespan|down regulation of insulin receptor signaling pathway involved in determination of adult lifespan|inhibition of insulin receptor signaling pathway involved in determination of adult lifespan|down-regulation of insulin receptor signaling pathway of determination of adult lifespan|negative regulation of insulin receptor signaling pathway of determination of adult lifespan|inhibition of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signalling pathway of determination of adult lifespan|negative regulation of insulin receptor signalling pathway of determination of adult lifespan|inhibition of insulin receptor signaling pathway of determination of adult lifespan|down regulation of daf-2 receptor signaling pathway of determination of adult lifespan http://purl.obolibrary.org/obo/GO_1903105 GO:1903104 biolink:BiologicalProcess regulation of insulin receptor signaling pathway involved in determination of adult lifespan Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan. go-plus.json regulation of daf-2 receptor signaling pathway of determination of adult lifespan|regulation of insulin receptor signalling pathway of determination of adult lifespan|regulation of insulin receptor signaling pathway of determination of adult lifespan http://purl.obolibrary.org/obo/GO_1903104 GO:1903103 biolink:CellularComponent potassium:proton antiporter complex A protein complex which is capable of potassium:proton antiporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903103 GO:1903102 biolink:BiologicalProcess 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. go-plus.json 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate synthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate formation http://purl.obolibrary.org/obo/GO_1903102 GO:1903101 biolink:BiologicalProcess 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. go-plus.json 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate degradation http://purl.obolibrary.org/obo/GO_1903101 GO:1903111 biolink:BiologicalProcess negative regulation of single-strand break repair via homologous recombination Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination. go-plus.json inhibition of single-strand break repair via homologous recombination|down regulation of single-strand break repair via homologous recombination|downregulation of single-strand break repair via homologous recombination|down-regulation of single-strand break repair via homologous recombination http://purl.obolibrary.org/obo/GO_1903111 GO:1903110 biolink:BiologicalProcess regulation of single-strand break repair via homologous recombination Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination. go-plus.json http://purl.obolibrary.org/obo/GO_1903110 UBERON:0011745 biolink:AnatomicalEntity pulmonary valve leaflets A cardiac valve leaflet that is part of a pulmonary valve. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011745 CHEBI:28579 biolink:ChemicalSubstance epsilon-caprolactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_28579 chebi_ph7_3 CHEBI:28578 biolink:ChemicalSubstance 2-hydroxyglutaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28578 GO:1903119 biolink:BiologicalProcess protein localization to actin cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. go-plus.json protein localisation in actin cytoskeleton|protein localization in actin cytoskeleton|protein localisation to actin cytoskeleton http://purl.obolibrary.org/obo/GO_1903119 GO:1903118 biolink:BiologicalProcess urate homeostasis Any process involved in the maintenance of an internal steady state of urate within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_1903118 GO:1903117 biolink:BiologicalProcess regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly Any process that modulates the frequency, rate or extent of actin filament organization involved in cytokinetic actomyosin contractile ring assembly. go-plus.json regulation of actin filament organisation of constriction ring assembly|regulation of actin filament organization of contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring formation|regulation of actin filament organization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organization of constriction ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organisation of contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring formation|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|regulation of regulation of actin filament localization of constriction ring assembly|regulation of actin filament organization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organization of cytokinesis, actomyosin ring formation|regulation of actin filament organisation of cytokinesis, contractile ring assembly|regulation of regulation of actin filament localization of contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring biosynthesis|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring formation http://purl.obolibrary.org/obo/GO_1903117 GO:1903116 biolink:BiologicalProcess positive regulation of actin filament-based movement Any process that activates or increases the frequency, rate or extent of actin filament-based movement. go-plus.json upregulation of actin filament-based movement|up regulation of actin filament-based movement|activation of actin filament-based movement|up-regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_1903116 UBERON:0011742 biolink:AnatomicalEntity aortic valve leaflet A cardiac valve leaflet that is part of a aortic valve. go-plus.json aortic valve leaflets http://purl.obolibrary.org/obo/UBERON_0011742 GO:1903115 biolink:BiologicalProcess regulation of actin filament-based movement Any process that modulates the frequency, rate or extent of actin filament-based movement. go-plus.json http://purl.obolibrary.org/obo/GO_1903115 UBERON:0011741 biolink:AnatomicalEntity cardiac valve leaflet go-plus.json valve leaflet http://purl.obolibrary.org/obo/UBERON_0011741 GO:1903114 biolink:CellularComponent silver ion transmembrane transporter complex A protein complex which is capable of silver ion transmembrane transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903114 GO:1903113 biolink:CellularComponent copper ion transmembrane transporter complex A protein complex which is capable of copper ion transmembrane transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903113 CHEBI:28573 biolink:ChemicalSubstance (R)-3-hydroxyoctanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28573 GO:1903112 biolink:BiologicalProcess positive regulation of single-strand break repair via homologous recombination Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination. go-plus.json up-regulation of single-strand break repair via homologous recombination|upregulation of single-strand break repair via homologous recombination|up regulation of single-strand break repair via homologous recombination|activation of single-strand break repair via homologous recombination http://purl.obolibrary.org/obo/GO_1903112 GO:1903122 biolink:BiologicalProcess negative regulation of TRAIL-activated apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway. go-plus.json negative regulation of TRAIL-activated extrinsic apoptotic signaling pathway|down-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|inhibition of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|inhibition of TRAIL-induced apoptotic signaling pathway|inhibition of TRAIL-activated extrinsic apoptotic signaling pathway|down regulation of TRAIL-activated apoptotic signaling pathway|downregulation of TRAIL-activated apoptotic signaling pathway|down regulation of TRAIL-induced apoptotic signaling pathway|down regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|downregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|downregulation of TRAIL-induced apoptotic signaling pathway|down regulation of TRAIL-activated extrinsic apoptotic signaling pathway|downregulation of TRAIL-activated extrinsic apoptotic signaling pathway|down-regulation of TRAIL-activated apoptotic signaling pathway|negative regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down-regulation of TRAIL-induced apoptotic signaling pathway|negative regulation of TRAIL-induced apoptotic signaling pathway|inhibition of TRAIL-activated apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1903122 PR:000050043 biolink:Protein lymphotoxin A tumor necrosis factor, TNF-like that is a translation product of the human LTA or LTB genes, or 1:1 orthologs thereof. go-plus.json fam:LT http://purl.obolibrary.org/obo/PR_000050043 GO:1903121 biolink:BiologicalProcess regulation of TRAIL-activated apoptotic signaling pathway Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway. go-plus.json regulation of TRAIL-induced apoptotic signaling pathway|regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|regulation of TRAIL-activated extrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_1903121 GO:1903120 biolink:BiologicalProcess protein localization to actin filament bundle A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. go-plus.json protein localisation to actin filament bundle|protein localization to actin cable|protein localization in actin filament bundle|protein localisation in actin filament bundle http://purl.obolibrary.org/obo/GO_1903120 CHEBI:7351 biolink:ChemicalSubstance N(4)-acetyl-L-2,4-diaminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7351 CHEBI:28549 biolink:ChemicalSubstance 3-(indol-3-yl)-2-oxobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28549 CHEBI:53508 biolink:ChemicalSubstance thyroxine sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53508 CHEBI:28548 biolink:ChemicalSubstance D-pinitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28548 chebi_ph7_3 CHEBI:28547 biolink:ChemicalSubstance D-glucuronate 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28547 CHEBI:28542 biolink:ChemicalSubstance 2-deoxy-D-ribofuranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28542 GO:1903129 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903129 CHEBI:28541 biolink:ChemicalSubstance N-acetylneuraminyl-(2->8)-N-acetylneuraminyl-(2->8)-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28541 PR:000001092 biolink:Protein interleukin-17 A protein that is a T cell-derived cytokine that may play an important role in the initiation or maintenance of the proinflammatory response. Except for IL-17B, all other IL-17 family members are homodimers containing five highly conserved cysteine residues forming characteristic cystein-knot structure, similar to that found in the TGF-beta-like cystine-knot (PR:000000008). This class consists of six cytokines. Among them, interleukin 17A (IL-17) and IL-17F are expressed by a novel subset of CD4+ helper T (Th) cells and play a critical role in inflammation and autoimmunity. On the other hand, IL-17E, also called IL-25, has been associated with allergic responses. go-plus.json IL17|fam:IL-17 http://purl.obolibrary.org/obo/PR_000001092 GO:1903128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903128 GO:1903127 biolink:BiologicalProcess positive regulation of centriole-centriole cohesion Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion. go-plus.json upregulation of centriole-centriole cohesion|up-regulation of centriole-centriole cohesion|activation of centriole-centriole cohesion|up regulation of centriole-centriole cohesion http://purl.obolibrary.org/obo/GO_1903127 PR:000001091 biolink:Protein interleukin-1 A protein with a core domain composition consisting of a propeptide region and an Interleukin-1 / 18 domain. go-plus.json http://purl.obolibrary.org/obo/PR_000001091 PR:000001094 biolink:Protein rhodopsin-like G-protein coupled receptor A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions. go-plus.json fam:rhodopsin|class A G-protein coupled receptor|class 1 G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000001094 GO:1903126 biolink:BiologicalProcess negative regulation of centriole-centriole cohesion Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion. go-plus.json down regulation of centriole-centriole cohesion|inhibition of centriole-centriole cohesion|down-regulation of centriole-centriole cohesion|downregulation of centriole-centriole cohesion http://purl.obolibrary.org/obo/GO_1903126 GO:1903125 biolink:BiologicalProcess negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity. go-plus.json negative regulation of TPx activity by peptidyl-threonine phosphorylation|negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation|negative regulation of TrxPx activity by peptidyl-threonine phosphorylation http://purl.obolibrary.org/obo/GO_1903125 PR:000001096 biolink:Protein Toll-like receptor A protein with a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582). go-plus.json fam:TLR http://purl.obolibrary.org/obo/PR_000001096 GO:1903124 biolink:BiologicalProcess negative regulation of thioredoxin peroxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity. go-plus.json inhibition of thiol peroxidase activity|down-regulation of TrxPx activity|negative regulation of TrxPx activity|downregulation of TPx activity|down-regulation of thioredoxin peroxidase activity|down regulation of TPx activity|inhibition of TPx activity|downregulation of TrxPx activity|inhibition of thioredoxin peroxidase activity|down regulation of thiol peroxidase activity|down regulation of TrxPx activity|inhibition of TrxPx activity|downregulation of thiol peroxidase activity|down-regulation of TPx activity|negative regulation of thiol peroxidase activity|down regulation of thioredoxin peroxidase activity|negative regulation of TPx activity|down-regulation of thiol peroxidase activity|downregulation of thioredoxin peroxidase activity http://purl.obolibrary.org/obo/GO_1903124 PR:000001095 biolink:Protein secretin-like G-protein coupled receptor A G-protein coupled receptor that contains the 7 transmembrane receptor (secretin family) domain (Pfam:PF00002) and has an amino-terminal segment of about 50-80 residues that contains conserved disulfide bonds and participates in ligand binding. go-plus.json subfamily B1 G-protein coupled receptor|class 2 G-protein coupled receptor|class B G-protein coupled receptor|fam:secretin http://purl.obolibrary.org/obo/PR_000001095 GO:1903123 biolink:BiologicalProcess regulation of thioredoxin peroxidase activity Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity. go-plus.json regulation of TPx activity|regulation of TrxPx activity|regulation of thiol peroxidase activity http://purl.obolibrary.org/obo/GO_1903123 GO:1903133 biolink:BiologicalProcess negative regulation of tube lumen cavitation Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation. go-plus.json inhibition of tube lumen cavitation http://purl.obolibrary.org/obo/GO_1903133 GO:1903132 biolink:BiologicalProcess regulation of tube lumen cavitation Any process that modulates the frequency, rate or extent of tube lumen cavitation. go-plus.json http://purl.obolibrary.org/obo/GO_1903132 GO:1903131 biolink:BiologicalProcess mononuclear cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. go-plus.json http://purl.obolibrary.org/obo/GO_1903131 GO:1903130 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1903130 CHEBI:28557 biolink:ChemicalSubstance cyclohexane-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28557 CHEBI:28556 biolink:ChemicalSubstance biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_28556 CHEBI:28558 biolink:ChemicalSubstance 2,5-dichloro-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28558 GO:1903139 biolink:BiologicalProcess positive regulation of cell wall integrity MAPK cascade Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis. go-plus.json positive regulation of MAPK cascade involved in cell wall organization or biogenesis|upregulation of cell integrity MAPK pathway|positive regulation of Pmk1 MAPK cell integrity signaling|positive regulation of Mpk1 cascade|up regulation of Mpk1 cascade|up regulation of Pmk1 MAPK cell integrity signaling|upregulation of MAPK cascade involved in cell wall organization or biogenesis|up-regulation of PMK1-MAPK signal transduction pathway|up-regulation of MAPK cascade involved in cell wall biogenesis|up-regulation of Slt2 cascade|up regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|up-regulation of cell wall biogenesis, MAPKKK cascade|activation of cell wall biogenesis, MAPKKK cascade|up-regulation of MAPKKK cascade involved in cell wall biogenesis|up regulation of cell integrity MAPK pathway|positive regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|activation of cell integrity MAPK pathway|positive regulation of cell integrity MAPK pathway|upregulation of Mpk1 cascade|upregulation of PMK1-MAPK signal transduction pathway|upregulation of Pmk1 MAPK cell integrity signaling|activation of Slt2 cascade|up regulation of MAPK cascade involved in cell wall organization or biogenesis|upregulation of MAPK cascade involved in cell wall biogenesis|activation of MAPK cascade involved in cell wall organization or biogenesis|activation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|positive regulation of Slt2 cascade|positive regulation of cell wall biogenesis, MAPKKK cascade|upregulation of MAPKKK cascade involved in cell wall biogenesis|up regulation of Slt2 cascade|up regulation of cell wall biogenesis, MAPKKK cascade|up-regulation of Mpk1 cascade|up-regulation of Pmk1 MAPK cell integrity signaling|up-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|up regulation of PMK1-MAPK signal transduction pathway|up-regulation of cell integrity MAPK pathway|positive regulation of PMK1-MAPK signal transduction pathway|up regulation of MAPK cascade involved in cell wall biogenesis|up-regulation of MAPK cascade involved in cell wall organization or biogenesis|positive regulation of MAPK cascade involved in cell wall biogenesis|activation of Pmk1 MAPK cell integrity signaling|activation of Mpk1 cascade|activation of PMK1-MAPK signal transduction pathway|up regulation of MAPKKK cascade involved in cell wall biogenesis|upregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|upregulation of Slt2 cascade|activation of MAPKKK cascade involved in cell wall biogenesis|activation of MAPK cascade involved in cell wall biogenesis|positive regulation of MAPKKK cascade involved in cell wall biogenesis|upregulation of cell wall biogenesis, MAPKKK cascade http://purl.obolibrary.org/obo/GO_1903139 GO:1903138 biolink:BiologicalProcess negative regulation of cell wall integrity MAPK cascade Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis. go-plus.json down regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|inhibition of Slt2 cascade|negative regulation of MAPKKK cascade involved in cell wall biogenesis|down-regulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of cell integrity MAPK pathway|downregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|downregulation of Pmk1 MAPK cell integrity signaling|negative regulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of Mpk1 cascade|down regulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of cell integrity MAPK pathway|inhibition of PMK1-MAPK signal transduction pathway|down regulation of Mpk1 cascade|down regulation of Pmk1 MAPK cell integrity signaling|inhibition of MAPKKK cascade involved in cell wall biogenesis|inhibition of MAPK cascade involved in cell wall biogenesis|downregulation of MAPK cascade involved in cell wall organization or biogenesis|down-regulation of Slt2 cascade|down-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|negative regulation of Slt2 cascade|negative regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|down regulation of PMK1-MAPK signal transduction pathway|inhibition of Pmk1 MAPK cell integrity signaling|down-regulation of cell wall biogenesis, MAPKKK cascade|negative regulation of cell wall biogenesis, MAPKKK cascade|inhibition of Mpk1 cascade|down regulation of MAPK cascade involved in cell wall biogenesis|negative regulation of cell integrity MAPK pathway|down-regulation of cell integrity MAPK pathway|downregulation of PMK1-MAPK signal transduction pathway|down-regulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of MAPK cascade involved in cell wall biogenesis|downregulation of Slt2 cascade|inhibition of cell integrity MAPK pathway|down regulation of MAPKKK cascade involved in cell wall biogenesis|downregulation of cell wall biogenesis, MAPKKK cascade|inhibition of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|inhibition of MAPK cascade involved in cell wall organization or biogenesis|downregulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of Slt2 cascade|down-regulation of PMK1-MAPK signal transduction pathway|negative regulation of PMK1-MAPK signal transduction pathway|down-regulation of Pmk1 MAPK cell integrity signaling|negative regulation of Mpk1 cascade|down-regulation of Mpk1 cascade|negative regulation of Pmk1 MAPK cell integrity signaling|down regulation of cell wall biogenesis, MAPKKK cascade|down-regulation of MAPK cascade involved in cell wall biogenesis|inhibition of cell wall biogenesis, MAPKKK cascade|negative regulation of MAPK cascade involved in cell wall biogenesis http://purl.obolibrary.org/obo/GO_1903138 CHEBI:28554 biolink:ChemicalSubstance ajugose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28554 chebi_ph7_3 GO:1903137 biolink:BiologicalProcess regulation of cell wall integrity MAPK cascade Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis. go-plus.json regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|regulation of cell integrity MAPK pathway|regulation of Mpk1 cascade|regulation of Pmk1 MAPK cell integrity signaling|regulation of PMK1-MAPK signal transduction pathway|regulation of MAPK cascade involved in cell wall biogenesis|regulation of MAPKKK cascade involved in cell wall biogenesis|regulation of MAPK cascade involved in cell wall organization or biogenesis|regulation of Slt2 cascade|regulation of cell wall biogenesis, MAPKKK cascade http://purl.obolibrary.org/obo/GO_1903137 GO:1903136 biolink:MolecularActivity cuprous ion binding Binding to a cuprous ion, copper(1+). go-plus.json Cu(I) binding|copper(1+) binding|Cu(+) binding http://purl.obolibrary.org/obo/GO_1903136 GO:1903135 biolink:MolecularActivity cupric ion binding Binding to a cupric ion, copper(2+). go-plus.json Cu(II) binding|copper(2+)binding|Cu(2+) binding http://purl.obolibrary.org/obo/GO_1903135 GO:1903134 biolink:BiologicalProcess obsolete trehalose catabolic process involved in cellular response to stress OBSOLETE. Any trehalose catabolic process that is involved in cellular response to stress. go-plus.json mycose catabolic process involved in cellular response to stress|mycose catabolism involved in cellular response to stress|mykose catabolic process involved in cellular response to stress|trehalose degradation involved in cellular response to stress|trehalose catabolism involved in cellular response to stress|trehalose breakdown involved in cellular response to stress|mykose catabolism involved in cellular response to stress http://purl.obolibrary.org/obo/GO_1903134 GO:1903144 biolink:CellularComponent actomyosin contractile ring actin filament Any actin filament that is part of a actomyosin contractile ring. go-plus.json actin filament of actomyosin contractile ring|actin filament of contractile actomyosin ring|actin filament of actomyosin ring|actin filament of cytokinetic ring|actin filament of CAR http://purl.obolibrary.org/obo/GO_1903144 GO:1903143 biolink:CellularComponent adrenomedullin receptor complex A transmembrane, G protein-coupled signalling receptor complex which is capable of adrenomedullin receptor activity. go-plus.json adrenomedullin receptor AM2 complex|adrenomedullin receptor AM1 complex http://purl.obolibrary.org/obo/GO_1903143 GO:1903142 biolink:BiologicalProcess positive regulation of establishment of endothelial barrier Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier. go-plus.json up-regulation of establishment of endothelial barrier|activation of establishment of endothelial barrier|up regulation of establishment of endothelial barrier|upregulation of establishment of endothelial barrier http://purl.obolibrary.org/obo/GO_1903142 GO:1903141 biolink:BiologicalProcess negative regulation of establishment of endothelial barrier Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier. go-plus.json down-regulation of establishment of endothelial barrier|downregulation of establishment of endothelial barrier|down regulation of establishment of endothelial barrier|inhibition of establishment of endothelial barrier http://purl.obolibrary.org/obo/GO_1903141 GO:1903140 biolink:BiologicalProcess regulation of establishment of endothelial barrier Any process that modulates the frequency, rate or extent of establishment of endothelial barrier. go-plus.json http://purl.obolibrary.org/obo/GO_1903140 CHEBI:28528 biolink:ChemicalSubstance 3-oxodecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28528 CHEBI:28526 biolink:ChemicalSubstance (KDO)2-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28526 NCBITaxon:2037 biolink:OrganismalEntity Actinomycetales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2037 CHEBI:28522 biolink:ChemicalSubstance 4-hydroxybutyryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28522 GO:1903149 biolink:MolecularActivity obsolete adenine transmembrane transporter activity involved in adenine import into cell OBSOLETE. Any adenine transmembrane transporter activity that is involved in adenine import into cell. go-plus.json adenine transmembrane transporter activity involved in adenine import into cell http://purl.obolibrary.org/obo/GO_1903149 GO:1903148 biolink:MolecularActivity obsolete uracil transmembrane transporter activity involved in uracil import into cell OBSOLETE. Any uracil transmembrane transporter activity that is involved in uracil import into cell. go-plus.json uracil/uridine permease activity involved in uracil import into cell|uracil transmembrane transporter activity involved in uracil import into cell http://purl.obolibrary.org/obo/GO_1903148 GO:1903147 biolink:BiologicalProcess negative regulation of autophagy of mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy. go-plus.json down regulation of mitochondrion degradation|downregulation of mitochondrion degradation|inhibition of mitophagy|down-regulation of mitochondrion degradation|down-regulation of mitophagy|inhibition of mitochondrion degradation|down regulation of mitochondrial degradation http://purl.obolibrary.org/obo/GO_1903147 GO:1903146 biolink:BiologicalProcess regulation of autophagy of mitochondrion Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process. go-plus.json regulation of mitochondrion degradation http://purl.obolibrary.org/obo/GO_1903146 GO:1903145 biolink:CellularComponent actin filament of cell cortex of cell tip Any actin filament that is part of a cell cortex of cell tip. go-plus.json microfilament of cell cortex of cell end|microfilament of cell cortex of cell tip|actin filament of cell cortex of cell end http://purl.obolibrary.org/obo/GO_1903145 GO:1903155 biolink:MolecularActivity obsolete glutathione transmembrane transporter activity involved in glutathione import into cell OBSOLETE. Any glutathione transmembrane transporter activity that is involved in glutathione import into cell. go-plus.json glutathione transmembrane transporter activity involved in glutathione uptake|glutathione transmembrane transporter activity involved in glutathione import into cell http://purl.obolibrary.org/obo/GO_1903155 GO:1903154 biolink:MolecularActivity obsolete glucose transmembrane transporter activity involved in glucose import into cell OBSOLETE. Any glucose transmembrane transporter activity that is involved in glucose import into cell. go-plus.json galactose/glucose (methylgalactoside) porter activity involved in glucose import into cell|glucose permease activity involved in glucose import into cell|glucose transmembrane transporter activity involved in glucose import into cell|lactose/glucose efflux transporter activity involved in glucose import into cell http://purl.obolibrary.org/obo/GO_1903154 GO:1903153 biolink:MolecularActivity obsolete ferrous iron transmembrane transporter activity involved in ferrous iron import into cell OBSOLETE. Any ferrous iron transmembrane transporter activity that is involved in ferrous iron import into cell. go-plus.json ferrous iron transmembrane transporter activity involved in ferrous ion import into cell|ferrous iron transmembrane transporter activity involved in ferrous iron import into cell http://purl.obolibrary.org/obo/GO_1903153 GO:1903152 biolink:MolecularActivity obsolete copper ion transmembrane transporter activity involved in copper ion import into cell OBSOLETE. Any copper ion transmembrane transporter activity that is involved in copper ion import into cell. go-plus.json copper ion transmembrane transporter activity involved in copper cation import into cell|copper ion transmembrane transporter activity involved in copper ion import into cell|plasma membrane copper transporter involved in copper ion import into cell|intracellular copper ion transporter involved in copper cation import into cell|intracellular copper ion transporter involved in copper ion import into cell|plasma membrane copper transporter involved in copper cation import into cell http://purl.obolibrary.org/obo/GO_1903152 GO:1903151 biolink:MolecularActivity obsolete carbohydrate transmembrane transporter activity involved in carbohydrate import into cell OBSOLETE. Any carbohydrate transmembrane transporter activity that is involved in carbohydrate import into cell. go-plus.json carbohydrate transmembrane transporter activity involved in carbohydrate import into cell|sugar transporter involved in carbohydrate import into cell http://purl.obolibrary.org/obo/GO_1903151 GO:1903150 biolink:MolecularActivity obsolete calcium ion transmembrane transporter activity involved in calcium ion import into cell OBSOLETE. Any calcium ion transmembrane transporter activity that is involved in calcium ion import into cell. go-plus.json calcium ion transmembrane transporter activity involved in calcium ion uptake into cell|calcium ion transmembrane transporter activity involved in calcium ion import into cell http://purl.obolibrary.org/obo/GO_1903150 CHEBI:7386 biolink:ChemicalSubstance 4-acetamidobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_7386 chebi_ph7_3 CHEBI:28538 biolink:ChemicalSubstance N(omega)-hydroxy-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28538 CHEBI:28537 biolink:ChemicalSubstance all-trans-dehydroretinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_28537 chebi_ph7_3 CHEBI:28536 biolink:ChemicalSubstance 3-hydroxyindolin-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28536 chebi_ph7_3 CHEBI:28531 biolink:ChemicalSubstance cob(I)yrinic acid a,c diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28531 CHEBI:28533 biolink:ChemicalSubstance 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28533 GO:1903159 biolink:MolecularActivity obsolete malate transmembrane transporter activity involved in malate import into cell OBSOLETE. Any malate transmembrane transporter activity that is involved in malate import into cell. go-plus.json dicarboxylate (succinate/fumarate/malate) antiporter activity involved in malate import into cell|malate transmembrane transporter activity involved in malate import into cell http://purl.obolibrary.org/obo/GO_1903159 GO:1903158 biolink:MolecularActivity obsolete L-glutamate transmembrane transporter activity involved in L-glutamate import into cell OBSOLETE. Any L-glutamate transmembrane transporter activity that is involved in L-glutamate import into cell. go-plus.json glutamate/aspartate porter activity involved in L-glutamate import into cell|glutamate/aspartate:sodium symporter activity involved in L-glutamate import into cell|L-glutamate transmembrane transporter activity involved in L-glutamate import into cell http://purl.obolibrary.org/obo/GO_1903158 GO:1903157 biolink:MolecularActivity obsolete iron ion transmembrane transporter activity involved in iron ion import into cell OBSOLETE. Any iron ion transmembrane transporter activity that is involved in iron ion import into cell. go-plus.json transmembrane iron permease activity involved in iron import into cell|transmembrane iron permease activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron ion import into cell|iron transporter activity involved in iron import into cell|zinc, iron permease activity involved in iron import into cell|iron transporter activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron import into cell|multicopper ferroxidase iron transport mediator activity involved in iron import into cell|zinc, iron permease activity involved in iron ion import into cell|transmembrane iron ion permease activity involved in iron import into cell|transmembrane iron ion permease activity involved in iron ion import into cell|multicopper ferroxidase iron transport mediator activity involved in iron ion import into cell http://purl.obolibrary.org/obo/GO_1903157 GO:1903156 biolink:MolecularActivity obsolete guanine transmembrane transporter activity involved in guanine import into cell OBSOLETE. Any guanine transmembrane transporter activity that is involved in guanine import into cell. go-plus.json guanine transmembrane transporter activity involved in guanine import into cell http://purl.obolibrary.org/obo/GO_1903156 GO:1903166 biolink:BiologicalProcess cellular response to polycyclic arene Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903166 UBERON:0011779 biolink:AnatomicalEntity nerve of head region A nerve that is part of a head. go-plus.json head nerve|cephalic nerve http://purl.obolibrary.org/obo/UBERON_0011779 UBERON:0011778 biolink:AnatomicalEntity motor nucleus of vagal nerve go-plus.json vagal lobe|nucleus motorius of nervi vagi|motor nucleus of X|motor nucleus X|nX http://purl.obolibrary.org/obo/UBERON_0011778 GO:1903165 biolink:BiologicalProcess response to polycyclic arene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1903165 UBERON:0011777 biolink:AnatomicalEntity nucleus of spinal cord A neural nucleus that is part of the spinal cord. go-plus.json spinal cord nucleus http://purl.obolibrary.org/obo/UBERON_0011777 GO:1903164 biolink:MolecularActivity obsolete succinate transmembrane transporter activity involved in succinate import into cell OBSOLETE. Any succinate transmembrane transporter activity that is involved in succinate import into cell. go-plus.json succinate transmembrane transporter activity involved in succinate import into cell|dicarboxylate (succinate/fumarate/malate) antiporter activity involved in succinate import into cell http://purl.obolibrary.org/obo/GO_1903164 GO:1903163 biolink:MolecularActivity obsolete sodium ion transmembrane transporter activity involved in sodium ion import into cell OBSOLETE. Any sodium ion transmembrane transporter activity that is involved in sodium ion import into cell. go-plus.json sodium transporter activity involved in sodium ion import into cell|sodium ion transmembrane transporter activity involved in sodium ion import into cell http://purl.obolibrary.org/obo/GO_1903163 GO:1903162 biolink:MolecularActivity obsolete serine transmembrane transporter activity involved in serine import into cell OBSOLETE. Any serine transmembrane transporter activity that is involved in serine import into cell. go-plus.json serine transmembrane transporter activity involved in serine import into cell http://purl.obolibrary.org/obo/GO_1903162 GO:1903161 biolink:MolecularActivity obsolete pantothenate transmembrane transporter activity involved in pantothenate import into cell OBSOLETE. Any pantothenate transmembrane transporter activity that is involved in pantothenate import into cell. go-plus.json pantothenate transmembrane transporter activity involved in pantothenate import into cell|vitamin B5 transmembrane transporter activity involved in pantothenate import into cell http://purl.obolibrary.org/obo/GO_1903161 GO:1903160 biolink:MolecularActivity obsolete nickel cation transmembrane transporter activity involved in nickel cation import into cell OBSOLETE. Any nickel cation transmembrane transporter activity that is involved in nickel cation import into cell. go-plus.json nickel cation transmembrane transporter activity involved in nickel cation import into cell|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity involved in nickel cation import into cell http://purl.obolibrary.org/obo/GO_1903160 CHEBI:28506 biolink:ChemicalSubstance arsonoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28506 CHEBI:28507 biolink:ChemicalSubstance cytidine 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28507 UBERON:0011775 biolink:AnatomicalEntity vagus nerve nucleus A cranial nerve nucleus that is associated with a vagus nerve. go-plus.json nucleus of Xth nerve|vagal nucleus|nucleus of vagal nerve|vagal X nucleus|vagus nucleus|nucleus of vagal X nerve|nucleus of vagus nerve|tenth cranial nerve nucleus|nodosal nucleus http://purl.obolibrary.org/obo/UBERON_0011775 GO:1903169 biolink:BiologicalProcess regulation of calcium ion transmembrane transport Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport. go-plus.json regulation of transmembrane calcium transport|regulation of calcium ion membrane transport http://purl.obolibrary.org/obo/GO_1903169 GO:1903168 biolink:BiologicalProcess positive regulation of pyrroline-5-carboxylate reductase activity Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity. go-plus.json up-regulation of L-proline oxidase activity|activation of L-proline oxidase activity|upregulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up regulation of P5CR activity|upregulation of pyrroline-5-carboxylate reductase activity|positive regulation of P5CR activity|activation of P5CR activity|up-regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|upregulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|upregulation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of L-proline oxidase activity|up regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up-regulation of pyrroline-5-carboxylate reductase activity|activation of pyrroline-5-carboxylate reductase activity|positive regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up regulation of L-proline oxidase activity|activation of L-proline-NAD(P)+ 5-oxidoreductase activity|upregulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up-regulation of P5CR activity|up regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up-regulation of 1-pyrroline-5-carboxylate reductase activity|activation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|activation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|upregulation of L-proline oxidase activity|up-regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|upregulation of P5CR activity|up regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up regulation of pyrroline-5-carboxylate reductase activity|activation of L-proline:NAD(P)+ 5-oxidoreductase activity|positive regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|positive regulation of 1-pyrroline-5-carboxylate reductase activity|up regulation of 1-pyrroline-5-carboxylate reductase activity|up-regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity http://purl.obolibrary.org/obo/GO_1903168 UBERON:0011773 biolink:AnatomicalEntity upper jaw opening An anatomical space that is part of a bone of upper jaw. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011773 GO:1903167 biolink:BiologicalProcess regulation of pyrroline-5-carboxylate reductase activity Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity. go-plus.json regulation of 1-pyrroline-5-carboxylate reductase activity|regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|regulation of L-proline oxidase activity|regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|regulation of P5CR activity http://purl.obolibrary.org/obo/GO_1903167 UBERON:0011772 biolink:AnatomicalEntity lower jaw opening An anatomical space that is part of a bone of lower jaw. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011772 GO:1903177 biolink:BiologicalProcess negative regulation of tyrosine 3-monooxygenase activity Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity. go-plus.json downregulation of tyrosine hydroxylase activity|down-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of L-tyrosine hydroxylase activity|negative regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|down regulation of tyrosine 3-hydroxylase activity|downregulation of tyrosine 3-hydroxylase activity|down-regulation of tyrosine 3-monooxygenase activity|negative regulation of tyrosine hydroxylase activity|down-regulation of tyrosine hydroxylase activity|down-regulation of L-tyrosine hydroxylase activity|negative regulation of L-tyrosine hydroxylase activity|downregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|inhibition of tyrosine 3-monooxygenase activity|down regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|down-regulation of tyrosine 3-hydroxylase activity|negative regulation of tyrosine 3-hydroxylase activity|inhibition of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|inhibition of tyrosine hydroxylase activity|inhibition of L-tyrosine hydroxylase activity|inhibition of tyrosine 3-hydroxylase activity|down regulation of tyrosine 3-monooxygenase activity|down regulation of tyrosine hydroxylase activity|down regulation of L-tyrosine hydroxylase activity|downregulation of tyrosine 3-monooxygenase activity http://purl.obolibrary.org/obo/GO_1903177 GO:1903176 biolink:BiologicalProcess regulation of tyrosine 3-monooxygenase activity Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity. go-plus.json regulation of tyrosine 3-hydroxylase activity|regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|regulation of tyrosine hydroxylase activity|regulation of L-tyrosine hydroxylase activity http://purl.obolibrary.org/obo/GO_1903176 UBERON:0011767 biolink:AnatomicalEntity right recurrent laryngeal nerve go-plus.json vagus X nerve right recurrent laryngeal branch|right recurrent laryngeal nerve|right recurrent laryngeal branch http://purl.obolibrary.org/obo/UBERON_0011767 GO:1903175 biolink:BiologicalProcess fatty alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of fatty alcohol. go-plus.json fatty alcohol anabolism|fatty alcohol biosynthesis|fatty alcohol synthesis|fatty alcohol formation http://purl.obolibrary.org/obo/GO_1903175 UBERON:0011766 biolink:AnatomicalEntity left recurrent laryngeal nerve go-plus.json left recurrent laryngeal branch|vagus X nerve left recurrent laryngeal branch|left recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0011766 GO:1903174 biolink:BiologicalProcess fatty alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of fatty alcohol. go-plus.json fatty alcohol degradation|fatty alcohol breakdown|fatty alcohol catabolism http://purl.obolibrary.org/obo/GO_1903174 GO:1903173 biolink:BiologicalProcess fatty alcohol metabolic process The chemical reactions and pathways involving fatty alcohol. go-plus.json fatty alcohol metabolism http://purl.obolibrary.org/obo/GO_1903173 GO:1903172 biolink:BiologicalProcess cellular carbon dioxide homeostasis Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_1903172 GO:1903171 biolink:BiologicalProcess carbon dioxide homeostasis Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_1903171 UBERON:0011769 biolink:AnatomicalEntity cartilaginous projection Anatomical projection that is composed of cartilage tissue. go-plus.json cartilaginous process|cartilage process http://purl.obolibrary.org/obo/UBERON_0011769 GO:1903170 biolink:BiologicalProcess negative regulation of calcium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport. go-plus.json inhibition of transmembrane calcium transport|down regulation of calcium ion transmembrane transport|negative regulation of calcium ion membrane transport|down-regulation of calcium ion membrane transport|downregulation of calcium ion transmembrane transport|down regulation of transmembrane calcium transport|downregulation of calcium ion membrane transport|downregulation of transmembrane calcium transport|down-regulation of calcium ion transmembrane transport|down regulation of calcium ion membrane transport|inhibition of calcium ion membrane transport|inhibition of calcium ion transmembrane transport|negative regulation of transmembrane calcium transport|down-regulation of transmembrane calcium transport http://purl.obolibrary.org/obo/GO_1903170 CHEBI:28517 biolink:ChemicalSubstance biphenyl-2,2',3-triol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28517 chebi_ph7_3 CHEBI:28516 biolink:ChemicalSubstance 1,2-dihydronaphthalene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28516 chebi_ph7_3 CHEBI:28518 biolink:ChemicalSubstance alpha-D-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28518 chebi_ph7_3 CHEBI:28514 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl-(1->4)-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28514 GO:1903179 biolink:BiologicalProcess regulation of dopamine biosynthetic process Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. go-plus.json regulation of dopamine formation|regulation of dopamine biosynthesis|regulation of dopamine anabolism|regulation of dopamine synthesis http://purl.obolibrary.org/obo/GO_1903179 GO:1903178 biolink:BiologicalProcess positive regulation of tyrosine 3-monooxygenase activity Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity. go-plus.json upregulation of tyrosine 3-hydroxylase activity|up regulation of tyrosine 3-monooxygenase activity|up regulation of tyrosine hydroxylase activity|activation of tyrosine 3-monooxygenase activity|up regulation of L-tyrosine hydroxylase activity|stimulation of TH activity|positive regulation of tyrosine hydroxylase activity|positive regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|activation of tyrosine hydroxylase activity|positive regulation of L-tyrosine hydroxylase activity|activation of L-tyrosine hydroxylase activity|up regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up regulation of tyrosine 3-hydroxylase activity|positive regulation of tyrosine 3-hydroxylase activity|activation of tyrosine 3-hydroxylase activity|up-regulation of tyrosine 3-monooxygenase activity|up-regulation of tyrosine hydroxylase activity|up-regulation of L-tyrosine hydroxylase activity|upregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up-regulation of tyrosine 3-hydroxylase activity|upregulation of tyrosine 3-monooxygenase activity|upregulation of tyrosine hydroxylase activity|up-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|upregulation of L-tyrosine hydroxylase activity|activation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|positive regulation of TH activity http://purl.obolibrary.org/obo/GO_1903178 GO:1903188 biolink:BiologicalProcess positive regulation of vitellogenesis Any process that activates or increases the frequency, rate or extent of vitellogenesis. go-plus.json up-regulation of vitellogenesis|activation of vitellogenesis|up-regulation of yolk production|upregulation of yolk production|up regulation of vitellogenesis|up regulation of yolk production|upregulation of vitellogenesis|positive regulation of yolk production|activation of yolk production http://purl.obolibrary.org/obo/GO_1903188 UBERON:0011757 biolink:AnatomicalEntity differentiated genital tubercle . go-plus.json primordial phallus|phallus primordialis|phallus http://purl.obolibrary.org/obo/UBERON_0011757 GO:1903187 biolink:BiologicalProcess negative regulation of vitellogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis. go-plus.json inhibition of yolk production|down-regulation of vitellogenesis|down regulation of yolk production|downregulation of vitellogenesis|downregulation of yolk production|down regulation of vitellogenesis|inhibition of vitellogenesis|negative regulation of yolk production|down-regulation of yolk production http://purl.obolibrary.org/obo/GO_1903187 GO:1903186 biolink:BiologicalProcess regulation of vitellogenesis Any process that modulates the frequency, rate or extent of vitellogenesis. go-plus.json regulation of yolk production http://purl.obolibrary.org/obo/GO_1903186 GO:1903185 biolink:BiologicalProcess L-dopa biosynthetic process The chemical reactions and pathways resulting in the formation of L-dopa. go-plus.json L-dopa anabolism|L-dopa synthesis|L-dopa biosynthesis|L-dopa formation http://purl.obolibrary.org/obo/GO_1903185 GO:1903184 biolink:BiologicalProcess L-dopa metabolic process The chemical reactions and pathways involving L-dopa. go-plus.json L-dopa metabolism http://purl.obolibrary.org/obo/GO_1903184 GO:1903183 biolink:BiologicalProcess negative regulation of SUMO transferase activity Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity. go-plus.json downregulation of SUMO ligase activity|downregulation of SUMO conjugating enzyme activity|downregulation of SMT3 conjugating enzyme|down regulation of SUMO ligase activity|inhibition of SUMO ligase activity|down regulation of SUMO conjugating enzyme activity|inhibition of SUMO conjugating enzyme activity|negative regulation of SMT3 conjugating enzyme|down-regulation of SMT3 conjugating enzyme|inhibition of SMT3 conjugating enzyme|down-regulation of SUMO ligase activity|negative regulation of SUMO conjugating enzyme activity|down-regulation of SUMO conjugating enzyme activity|down regulation of SMT3 conjugating enzyme http://purl.obolibrary.org/obo/GO_1903183 GO:1903182 biolink:BiologicalProcess regulation of SUMO transferase activity Any process that modulates the frequency, rate or extent of SUMO ligase activity. go-plus.json regulation of SMT3 conjugating enzyme|regulation of SUMO conjugating enzyme activity http://purl.obolibrary.org/obo/GO_1903182 GO:1903181 biolink:BiologicalProcess positive regulation of dopamine biosynthetic process Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. go-plus.json up regulation of dopamine anabolism|positive regulation of dopamine synthesis|up regulation of dopamine synthesis|positive regulation of dopamine formation|up-regulation of dopamine biosynthesis|up-regulation of dopamine biosynthetic process|up regulation of dopamine formation|upregulation of dopamine anabolism|upregulation of dopamine synthesis|upregulation of dopamine biosynthetic process|upregulation of dopamine biosynthesis|upregulation of dopamine formation|up-regulation of dopamine anabolism|activation of dopamine anabolism|up-regulation of dopamine synthesis|activation of dopamine synthesis|up regulation of dopamine biosynthesis|up regulation of dopamine biosynthetic process|up-regulation of dopamine formation|activation of dopamine formation|positive regulation of dopamine biosynthesis|activation of dopamine biosynthetic process|activation of dopamine biosynthesis|positive regulation of dopamine anabolism http://purl.obolibrary.org/obo/GO_1903181 GO:1903180 biolink:BiologicalProcess negative regulation of dopamine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. go-plus.json negative regulation of dopamine formation|down-regulation of dopamine formation|downregulation of dopamine anabolism|inhibition of dopamine biosynthetic process|inhibition of dopamine biosynthesis|down regulation of dopamine anabolism|downregulation of dopamine synthesis|inhibition of dopamine anabolism|downregulation of dopamine formation|down regulation of dopamine synthesis|inhibition of dopamine synthesis|down regulation of dopamine formation|inhibition of dopamine formation|down regulation of dopamine biosynthetic process|down regulation of dopamine biosynthesis|downregulation of dopamine biosynthesis|downregulation of dopamine biosynthetic process|negative regulation of dopamine anabolism|down-regulation of dopamine anabolism|negative regulation of dopamine synthesis|down-regulation of dopamine synthesis|negative regulation of dopamine biosynthesis|down-regulation of dopamine biosynthetic process|down-regulation of dopamine biosynthesis http://purl.obolibrary.org/obo/GO_1903180 PR:000050029 biolink:Protein thyrotropin-releasing hormone receptor A rhodopsin-like G-protein coupled receptor that has thyrotropin-releasing hormone receptor activity. go-plus.json http://purl.obolibrary.org/obo/PR_000050029 CHEBI:77450 biolink:ChemicalSubstance dicarboxylic acid monoamide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77450 chebi_ph7_3 CHEBI:864 biolink:ChemicalSubstance (S)-2,3,4,5-tetrahydrodipicolinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_864 CHEBI:53487 biolink:ChemicalSubstance all-cis-docosa-7,10,13,16-tetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53487 NCBITaxon:2085 biolink:OrganismalEntity Mycoplasmatales go-plus.json Paramycetales|Mycoplasmas|Mollicutales|Pleuropneumoniales|The Mycoplasmas|Borrelomycetales http://purl.obolibrary.org/obo/NCBITaxon_2085 CHEBI:53486 biolink:ChemicalSubstance all-cis-icosa-8,11,14-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53486 CHEBI:77452 biolink:ChemicalSubstance 2-deoxystreptamine cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_77452 chebi_ph7_3 CHEBI:53488 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53488 CHEBI:77456 biolink:ChemicalSubstance 2-iminopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77456 CHEBI:77460 biolink:ChemicalSubstance L-aminoacyl-L-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77460 chebi_ph7_3 CHEBI:77465 biolink:ChemicalSubstance 1-oleylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77465 chebi_ph7_3 NCBITaxon:2097 biolink:OrganismalEntity Mycoplasma genitalium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2097 NCBITaxon:2093 biolink:OrganismalEntity Mycoplasma go-plus.json Pleuropneumonia|Asterococcus|Haemobartonella|Borrelomyces|Eperythrozoon|Asteromyces|Bovimyces http://purl.obolibrary.org/obo/NCBITaxon_2093 CHEBI:77469 biolink:ChemicalSubstance 1-pentadecylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77469 chebi_ph7_3 CHEBI:77468 biolink:ChemicalSubstance pentadecan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77468 chebi_ph7_3 NCBITaxon:2092 biolink:OrganismalEntity Mycoplasmataceae go-plus.json Parasitaceae|Borrelomycetaceae|Pleuropneumoniaceae http://purl.obolibrary.org/obo/NCBITaxon_2092 CHEBI:77467 biolink:ChemicalSubstance 1-tetradecylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77467 chebi_ph7_3 CHEBI:77466 biolink:ChemicalSubstance 1-dodecylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77466 chebi_ph7_3 GO:0004987 biolink:MolecularActivity obsolete kappa-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins. Wikipedia:Kappa_Opioid_receptor go-plus.json kappa-opioid receptor activity http://purl.obolibrary.org/obo/GO_0004987 GO:0004986 biolink:MolecularActivity obsolete delta-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands. Wikipedia:Delta_Opioid_receptor go-plus.json delta-opioid receptor activity http://purl.obolibrary.org/obo/GO_0004986 GO:0004989 biolink:MolecularActivity octopamine receptor activity Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist. go-plus.json http://purl.obolibrary.org/obo/GO_0004989 GO:0004988 biolink:MolecularActivity obsolete mu-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins. Wikipedia:Mu_Opioid_receptor go-plus.json mu-opioid receptor activity http://purl.obolibrary.org/obo/GO_0004988 GO:0004983 biolink:MolecularActivity neuropeptide Y receptor activity Combining with neuropeptide Y to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004983 GO:0004982 biolink:MolecularActivity N-formyl peptide receptor activity Combining with an N-formyl peptide to initiate a change in cell activity. go-plus.json Fmet-leu-phe receptor http://purl.obolibrary.org/obo/GO_0004982 GO:0004985 biolink:MolecularActivity G protein-coupled opioid receptor activity Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json opioid receptor activity http://purl.obolibrary.org/obo/GO_0004985 GO:0004984 biolink:MolecularActivity olfactory receptor activity Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell. go-plus.json odorant receptor activity http://purl.obolibrary.org/obo/GO_0004984 GO:0004981 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004981 GO:0004980 biolink:MolecularActivity melanocyte-stimulating hormone receptor activity Combining with melanocyte-stimulating hormone to initiate a change in cell activity. go-plus.json MSH receptor activity|melanocyte stimulating hormone receptor activity|melanophore-stimulating hormone receptor activity|MSHR activity http://purl.obolibrary.org/obo/GO_0004980 CHEBI:77472 biolink:ChemicalSubstance 1-octadecylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77472 chebi_ph7_3 CHEBI:77471 biolink:ChemicalSubstance 1-heptadecylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77471 chebi_ph7_3 CHEBI:77470 biolink:ChemicalSubstance heptadecan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77470 chebi_ph7_3 PR:000001004 biolink:Protein CD4 molecule A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. go-plus.json T-cell surface glycoprotein CD4|T-cell surface antigen T4/Leu-3|T-cell differentiation antigen L3T4|CD4 http://purl.obolibrary.org/obo/PR_000001004 CHEBI:77475 biolink:ChemicalSubstance 1-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77475 chebi_ph7_3 CHEBI:77474 biolink:ChemicalSubstance (9Z,12Z,15Z)-octadecatrien-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77474 chebi_ph7_3 CHEBI:77473 biolink:ChemicalSubstance 1-(9Z,12Z)-octadecadienylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77473 chebi_ph7_3 CHEBI:53460 biolink:ChemicalSubstance all-cis-icosa-11,14,17-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53460 NCBITaxon:2062 biolink:OrganismalEntity Streptomycetaceae go-plus.json Actinoplanaceae http://purl.obolibrary.org/obo/NCBITaxon_2062 CHEBI:53463 biolink:ChemicalSubstance heptasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_53463 GO:0004998 biolink:MolecularActivity transferrin receptor activity Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0004998 GO:0004997 biolink:MolecularActivity thyrotropin-releasing hormone receptor activity Combining with thyrotropin-releasing hormone to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004997 GO:0004999 biolink:MolecularActivity vasoactive intestinal polypeptide receptor activity Combining with vasoactive intestinal polypeptide to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004999 GO:0004994 biolink:MolecularActivity somatostatin receptor activity Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28). go-plus.json SRIF receptor activity|SST receptor activity|growth hormone-inhibiting hormone receptor activity|GHIH receptor activity|somatotrophin release inhibiting factor receptor activity http://purl.obolibrary.org/obo/GO_0004994 GO:0004993 biolink:MolecularActivity G protein-coupled serotonin receptor activity Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. Wikipedia:5-HT_receptor go-plus.json 5-HT receptor|5-hydroxytryptamine receptor|G protein coupled serotonin receptor activity|G-protein coupled serotonin receptor activity http://purl.obolibrary.org/obo/GO_0004993 GO:0004996 biolink:MolecularActivity thyroid-stimulating hormone receptor activity Combining with thyroid-stimulating hormone to initiate a change in cell activity. Wikipedia:Thyrotropin_receptor go-plus.json TSH receptor activity|thyrotropin receptor|thyroid stimulating hormone receptor activity http://purl.obolibrary.org/obo/GO_0004996 GO:0004995 biolink:MolecularActivity tachykinin receptor activity Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein. go-plus.json http://purl.obolibrary.org/obo/GO_0004995 GO:0004990 biolink:MolecularActivity oxytocin receptor activity Combining with oxytocin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004990 GO:0004992 biolink:MolecularActivity platelet activating factor receptor activity Combining with platelet activating factor to initiate a change in cell activity. go-plus.json PAF receptor activity http://purl.obolibrary.org/obo/GO_0004992 GO:0004991 biolink:MolecularActivity parathyroid hormone receptor activity Combining with parathyroid hormone to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004991 CHEBI:77483 biolink:ChemicalSubstance (4R)-4-hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77483 CHEBI:77482 biolink:ChemicalSubstance (3S)-3-hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77482 CHEBI:77484 biolink:ChemicalSubstance EC 1.1.1.25 (shikimate dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77484 CHEBI:53455 biolink:ChemicalSubstance D-xylopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_53455 chebi_ph7_3 CHEBI:77488 biolink:ChemicalSubstance (3S)-3-hydroxy-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77488 GO:0004965 biolink:MolecularActivity G protein-coupled GABA receptor activity Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. Reactome:R-HSA-1013013|Reactome:R-HSA-1013012 go-plus.json GABA-B receptor activity|G-protein coupled GABA receptor activity|metabotropic GABA receptor http://purl.obolibrary.org/obo/GO_0004965 GO:0004964 biolink:MolecularActivity luteinizing hormone receptor activity Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity. go-plus.json LH receptor|LHR|lutropin receptor|lutropin-choriogonadotropic hormone receptor http://purl.obolibrary.org/obo/GO_0004964 GO:0004967 biolink:MolecularActivity glucagon receptor activity Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0004967 GO:0004966 biolink:MolecularActivity galanin receptor activity Combining with galanin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004966 GO:0004961 biolink:MolecularActivity thromboxane A2 receptor activity Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein. go-plus.json TXA2 receptor activity|TXA(2) receptor activity http://purl.obolibrary.org/obo/GO_0004961 GO:0004960 biolink:MolecularActivity thromboxane receptor activity Combining with a thromboxane (TXA) to initiate a change in cell activity. go-plus.json TXA receptor activity http://purl.obolibrary.org/obo/GO_0004960 GO:0004963 biolink:MolecularActivity follicle-stimulating hormone receptor activity Combining with follicle-stimulating hormone to initiate a change in cell activity. go-plus.json FSH receptor activity|follicle stimulating hormone receptor activity http://purl.obolibrary.org/obo/GO_0004963 GO:0004962 biolink:MolecularActivity endothelin receptor activity Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json endothelin-B receptor activity|endothelin-A receptor activity http://purl.obolibrary.org/obo/GO_0004962 CHEBI:28488 biolink:ChemicalSubstance m-xylene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28488 chebi_ph7_3 CHEBI:28484 biolink:ChemicalSubstance isovaleric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28484 CHEBI:28490 biolink:ChemicalSubstance L-methionine sulfoximine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28490 UBERON:0011823 biolink:AnatomicalEntity dense connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets go-plus.json http://purl.obolibrary.org/obo/UBERON_0011823 UBERON:0011822 biolink:AnatomicalEntity dense irregular connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. go-plus.json typus irregularis (textus connectivus collagenosus compactus)|irregular dense connective tissue http://purl.obolibrary.org/obo/UBERON_0011822 UBERON:0011821 biolink:AnatomicalEntity irregular connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011821 CHEBI:28492 biolink:ChemicalSubstance 5-methylbarbituric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28492 UBERON:0011820 biolink:AnatomicalEntity atrioventricular region An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart. go-plus.json AV segment|atrial ventricular junction|AV region|atrioventricular junction|atrioventricular segment http://purl.obolibrary.org/obo/UBERON_0011820 CHEBI:77494 biolink:ChemicalSubstance 1-arachidonoylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77494 chebi_ph7_3 CHEBI:77493 biolink:ChemicalSubstance 1-linoleoylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77493 chebi_ph7_3 CHEBI:77492 biolink:ChemicalSubstance 1-oleoylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77492 chebi_ph7_3 UBERON:0011825 biolink:AnatomicalEntity loose connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. go-plus.json textus connectivus laxus|textus connectivus collagenosus laxus http://purl.obolibrary.org/obo/UBERON_0011825 UBERON:0011824 biolink:AnatomicalEntity fibrous connective tissue go-plus.json http://purl.obolibrary.org/obo/UBERON_0011824 CHEBI:77497 biolink:ChemicalSubstance (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77497 GO:0004969 biolink:MolecularActivity histamine receptor activity Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. go-plus.json http://purl.obolibrary.org/obo/GO_0004969 GO:0004968 biolink:MolecularActivity gonadotropin-releasing hormone receptor activity Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. go-plus.json GnRH receptor activity|gonadotrophin-releasing hormone receptor activity http://purl.obolibrary.org/obo/GO_0004968 CHEBI:77499 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77499 GO:0004976 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004976 GO:0004975 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004975 GO:0004978 biolink:MolecularActivity corticotropin receptor activity Combining with corticotropin to initiate a change in cell activity. go-plus.json adrenocorticotropic hormone receptor activity|ACTH receptor activity|adrenocorticotropin receptor activity http://purl.obolibrary.org/obo/GO_0004978 GO:0004977 biolink:MolecularActivity melanocortin receptor activity Combining with melanocortin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004977 GO:0004972 biolink:MolecularActivity NMDA glutamate receptor activity An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages. Wikipedia:NMDA_receptor go-plus.json N-methyl-D-aspartate selective glutamate receptor activity|NMDA receptor http://purl.obolibrary.org/obo/GO_0004972 GO:0004971 biolink:MolecularActivity AMPA glutamate receptor activity An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium. go-plus.json alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|AMPA receptor activity http://purl.obolibrary.org/obo/GO_0004971 GO:0004974 biolink:MolecularActivity leukotriene receptor activity Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0004974 GO:0004973 biolink:MolecularActivity obsolete N-methyl-D-aspartate receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json N-methyl-D-aspartate receptor-associated protein activity http://purl.obolibrary.org/obo/GO_0004973 CHEBI:28498 biolink:ChemicalSubstance acadesine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28498 chebi_ph7_3 CHEBI:28497 biolink:ChemicalSubstance N-acetyl-beta-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28497 chebi_ph7_3 GO:0004970 biolink:MolecularActivity ionotropic glutamate receptor activity Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0004970 CHEBI:28499 biolink:ChemicalSubstance kaempferol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28499 CHEBI:28494 biolink:ChemicalSubstance cardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28494 CHEBI:28493 biolink:ChemicalSubstance decanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_28493 CHEBI:28496 biolink:ChemicalSubstance N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28496 UBERON:0011814 biolink:AnatomicalEntity non-neurogenic ectodermal placode Ectodermal placode that does not develop into a component of the nervous system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0011814 UBERON:0011819 biolink:AnatomicalEntity lumen of atrioventricular canal A tube lumen that is part of a atrioventricular canal. go-plus.json AVC lumen|lumen of AVC|cavity of atrioventricular canal http://purl.obolibrary.org/obo/UBERON_0011819 CHEBI:53431 biolink:ChemicalSubstance chain carrier go-plus.json http://purl.obolibrary.org/obo/CHEBI_53431 UBERON:0011817 biolink:AnatomicalEntity skin appendage placode An ectodermal placode that gives rise to any of the cutaneous appendages that protrude from the skin epidermis (heair, feathers, epidermal scales). go-plus.json cutaneous appendage follicle placode|skin follicle placode http://purl.obolibrary.org/obo/UBERON_0011817 GO:0004979 biolink:MolecularActivity beta-endorphin receptor activity Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC). go-plus.json mu-opioid receptor activity http://purl.obolibrary.org/obo/GO_0004979 GO:0004943 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004943 GO:0004942 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004942 GO:0004945 biolink:MolecularActivity angiotensin type II receptor activity An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms. go-plus.json http://purl.obolibrary.org/obo/GO_0004945 GO:0004944 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004944 CHEBI:28469 biolink:ChemicalSubstance 4-(hydroxyamino)quinoline N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28469 chebi_ph7_3 CHEBI:28468 biolink:ChemicalSubstance 1-O-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28468 GO:0004941 biolink:MolecularActivity beta2-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors. go-plus.json beta2 adrenoceptor http://purl.obolibrary.org/obo/GO_0004941 GO:0004940 biolink:MolecularActivity beta1-adrenergic receptor activity Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors. go-plus.json beta1 adrenoceptor http://purl.obolibrary.org/obo/GO_0004940 CHEBI:28465 biolink:ChemicalSubstance acetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_28465 chebi_ph7_3 CHEBI:28464 biolink:ChemicalSubstance 4-hydroxy-6-methylpretetramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28464 chebi_ph7_3 CHEBI:28461 biolink:ChemicalSubstance 4-amino-4-de(dimethylamino)anhydrotetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28461 CHEBI:28460 biolink:ChemicalSubstance maltotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28460 chebi_ph7_3 CHEBI:28462 biolink:ChemicalSubstance ajmaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28462 CHEBI:28470 biolink:ChemicalSubstance 3,5-dihydro-4H-imidazol-4-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28470 chebi_ph7_3 GO:0004947 biolink:MolecularActivity bradykinin receptor activity Combining with bradykinin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004947 GO:0004946 biolink:MolecularActivity bombesin receptor activity Combining with bombesin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004946 GO:0004949 biolink:MolecularActivity cannabinoid receptor activity Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids. go-plus.json cannaboid receptor|endocannabinoid receptor activity http://purl.obolibrary.org/obo/GO_0004949 GO:0004948 biolink:MolecularActivity calcitonin receptor activity Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json http://purl.obolibrary.org/obo/GO_0004948 GO:0004954 biolink:MolecularActivity prostanoid receptor activity Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004954 GO:0004953 biolink:MolecularActivity icosanoid receptor activity Combining with an icosanoid to initiate a change in cell activity. go-plus.json eicosanoid receptor activity http://purl.obolibrary.org/obo/GO_0004953 GO:0004956 biolink:MolecularActivity prostaglandin D receptor activity Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity. go-plus.json PGD receptor activity|PGD(2) receptor activity http://purl.obolibrary.org/obo/GO_0004956 GO:0004955 biolink:MolecularActivity prostaglandin receptor activity Combining with a prostaglandin (PG) to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004955 GO:0004950 biolink:MolecularActivity chemokine receptor activity Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0004950 CHEBI:28479 biolink:ChemicalSubstance D-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28479 GO:0004952 biolink:MolecularActivity dopamine neurotransmitter receptor activity Combining with the neurotransmitter dopamine to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0004952 GO:0004951 biolink:MolecularActivity cholecystokinin receptor activity Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone. go-plus.json CCK receptor activity http://purl.obolibrary.org/obo/GO_0004951 CHEBI:28478 biolink:ChemicalSubstance (2-hydroxyphenyl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28478 CHEBI:28477 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28477 chebi_ph7_3 CHEBI:28471 biolink:ChemicalSubstance alpha-D-GalNAc-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28471 chebi_ph7_3 GO:1903100 biolink:BiologicalProcess 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. go-plus.json 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolism http://purl.obolibrary.org/obo/GO_1903100 CHEBI:28480 biolink:ChemicalSubstance aldehydo-L-lyxose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28480 chebi_ph7_3 GO:0004958 biolink:MolecularActivity prostaglandin F receptor activity Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity. go-plus.json PGF receptor activity|PGF(2-alpha) receptor activity http://purl.obolibrary.org/obo/GO_0004958 GO:0004957 biolink:MolecularActivity prostaglandin E receptor activity Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity. go-plus.json PGE(2) receptor activity|PGE receptor activity http://purl.obolibrary.org/obo/GO_0004957 GO:0004959 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004959 CHEBI:133050 biolink:ChemicalSubstance N-tetradecanoylglycyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_133050 chebi_ph7_3 CHEBI:133063 biolink:ChemicalSubstance N(alpha)-acetyl-L-methionyl-L-aspartyl(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133063 chebi_ph7_3 CHEBI:133039 biolink:ChemicalSubstance 1-(2-aminophenyl)decane-1,3-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_133039 chebi_ph7_3 CHEBI:77404 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77404 CHEBI:77409 biolink:ChemicalSubstance (3S)-3-hydroxy-L-lysine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77409 chebi_ph7_3 CHEBI:133045 biolink:ChemicalSubstance L-methionyl-L-aspartyl zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133045 chebi_ph7_3 CHEBI:133042 biolink:ChemicalSubstance L-leucyl-L-aspartyl zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133042 chebi_ph7_3 CHEBI:77403 biolink:ChemicalSubstance (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77403 CHEBI:133041 biolink:ChemicalSubstance L-leucyl-L-glutamyl zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133041 chebi_ph7_3 CHEBI:133044 biolink:ChemicalSubstance L-leucyl-L-arginyl(2+) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_133044 chebi_ph7_3 CHEBI:133043 biolink:ChemicalSubstance L-leucyl-L-lysyl(2+) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_133043 chebi_ph7_3 CHEBI:77400 biolink:ChemicalSubstance 2-aminopentanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_77400 chebi_ph7_3 CHEBI:77417 biolink:ChemicalSubstance tetradecan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77417 chebi_ph7_3 CHEBI:133012 biolink:ChemicalSubstance 5a,11a-dehydrooxytetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133012 chebi_ph7_3 CHEBI:77410 biolink:ChemicalSubstance (4R)-4-hydroxy-L-lysine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77410 chebi_ph7_3 CHEBI:133011 biolink:ChemicalSubstance oxytetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_133011 chebi_ph7_3 CHEBI:77411 biolink:ChemicalSubstance (3S)-3-hydroxy-L-ornithine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77411 chebi_ph7_3 CHEBI:77429 biolink:ChemicalSubstance 1-palmitylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77429 chebi_ph7_3 CHEBI:77427 biolink:ChemicalSubstance (3R)-3-carboxy-3-hydroxypropanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77427 chebi_ph7_3 PO:0005849 biolink:OntologyClass primary xylem A portion of xylem (PO:0005352) tissue that develops from the procambium (PO:0025275). go-plus.json 一次木部 (Japanese, exact)|portion of primary xylem tissue (exact)|xilema primario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0005849 CHEBI:133029 biolink:ChemicalSubstance S-octanoyl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_133029 chebi_ph7_3 CHEBI:77425 biolink:ChemicalSubstance EC 1.1.1.188 (prostaglandin-F synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_77425 CHEBI:857 biolink:ChemicalSubstance 2,2'-iminodipropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_857 CHEBI:519567 biolink:ChemicalSubstance 2'-O-methylisoliquiritigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_519567 chebi_ph7_3 CHEBI:133004 biolink:ChemicalSubstance bisbenzylisoquinoline alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133004 CHEBI:133000 biolink:ChemicalSubstance pregnenolone sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133000 chebi_ph7_3 CHEBI:77444 biolink:ChemicalSubstance 1-undecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_77444 chebi_ph7_3 GO:1903069 biolink:BiologicalProcess regulation of ER-associated ubiquitin-dependent protein catabolic process Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. go-plus.json regulation of ERAD|regulation of ER-associated protein degradation|regulation of ER-associated protein catabolism|regulation of ER-associated protein breakdown|regulation of endoplasmic reticulum-associated protein catabolic process|regulation of endoplasmic reticulum-associated protein catabolism|regulation of ER-associated protein catabolic process http://purl.obolibrary.org/obo/GO_1903069 GO:1903068 biolink:BiologicalProcess positive regulation of protein localization to cell tip Any process that activates or increases the frequency, rate or extent of protein localization to cell tip. go-plus.json up regulation of protein localization to cell tip|upregulation of protein localisation to cell tip|upregulation of protein localization to cell tip|up-regulation of protein localisation to cell tip|activation of protein localisation to cell tip|up-regulation of protein localization to cell tip|activation of protein localization to cell tip|positive regulation of protein localisation to cell tip|up regulation of protein localisation to cell tip http://purl.obolibrary.org/obo/GO_1903068 GO:1903078 biolink:BiologicalProcess positive regulation of protein localization to plasma membrane Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. go-plus.json positive regulation of protein localisation in plasma membrane|activation of protein localisation in plasma membrane|activation of protein-plasma membrane targeting|up regulation of protein localization to plasma membrane|activation of protein targeting to plasma membrane|positive regulation of protein targeting to plasma membrane|activation of protein localization to plasma membrane|up-regulation of protein localization in plasma membrane|up regulation of protein-plasma membrane targeting|positive regulation of establishment of protein localization to plasma membrane|positive regulation of establishment of protein localisation in plasma membrane|positive regulation of protein-plasma membrane targeting|up-regulation of protein targeting to plasma membrane|up-regulation of protein localisation in plasma membrane|upregulation of protein localization in plasma membrane|up-regulation of protein localization to plasma membrane|up-regulation of protein-plasma membrane targeting|up regulation of protein targeting to plasma membrane|upregulation of protein localisation in plasma membrane|upregulation of protein localization to plasma membrane|up regulation of protein localization in plasma membrane|activation of protein localization in plasma membrane|positive regulation of protein localization in plasma membrane|upregulation of protein-plasma membrane targeting|upregulation of protein targeting to plasma membrane|up regulation of protein localisation in plasma membrane http://purl.obolibrary.org/obo/GO_1903078 GO:1903077 biolink:BiologicalProcess negative regulation of protein localization to plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. go-plus.json negative regulation of establishment of protein localization to plasma membrane|downregulation of protein-plasma membrane targeting|negative regulation of establishment of protein localisation in plasma membrane|inhibition of protein localization in plasma membrane|down-regulation of protein localisation in plasma membrane|down-regulation of protein localization to plasma membrane|negative regulation of protein localisation in plasma membrane|negative regulation of protein-plasma membrane targeting|down-regulation of protein-plasma membrane targeting|inhibition of protein localisation in plasma membrane|inhibition of protein-plasma membrane targeting|inhibition of protein localization to plasma membrane|down-regulation of protein targeting to plasma membrane|down regulation of protein localization in plasma membrane|downregulation of protein localization in plasma membrane|negative regulation of establishment of protein localization in plasma membrane|inhibition of protein targeting to plasma membrane|down regulation of protein localisation in plasma membrane|downregulation of protein targeting to plasma membrane|down regulation of protein localization to plasma membrane|downregulation of protein localisation in plasma membrane|down regulation of protein targeting to plasma membrane|down-regulation of protein localization in plasma membrane|negative regulation of protein localization in plasma membrane|down regulation of protein-plasma membrane targeting|negative regulation of protein targeting to plasma membrane|downregulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1903077 GO:1903076 biolink:BiologicalProcess regulation of protein localization to plasma membrane Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. go-plus.json regulation of establishment of protein localization in plasma membrane|regulation of protein targeting to plasma membrane|regulation of establishment of protein localization to plasma membrane|regulation of establishment of protein localisation in plasma membrane|regulation of protein localization in plasma membrane|regulation of protein localisation in plasma membrane|regulation of protein-plasma membrane targeting http://purl.obolibrary.org/obo/GO_1903076 GO:1903075 biolink:BiologicalProcess pyridoxine import across plasma membrane The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json pyridoxine import into cell http://purl.obolibrary.org/obo/GO_1903075 GO:1903074 biolink:BiologicalProcess TRAIL death-inducing signaling complex assembly The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex. go-plus.json TRAIL DISC assembly|TRAIL death-inducing signalling complex formation|TRAIL death-inducing signaling complex formation|TRAIL death-inducing signalling complex assembly|TRAIL DISC formation http://purl.obolibrary.org/obo/GO_1903074 GO:1903073 biolink:BiologicalProcess negative regulation of death-inducing signaling complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly. go-plus.json down regulation of death-inducing signaling complex assembly|down regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|downregulation of DISC assembly|downregulation of death-inducing signalling complex assembly|down regulation of death domain-mediated complex assembly|downregulation of DISC formation|inhibition of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of death-inducing signaling complex formation|downregulation of death-inducing signaling complex assembly|inhibition of death domain-mediated complex assembly|inhibition of death-inducing signaling complex formation|down-regulation of DD-mediated complex assembly|negative regulation of DD-mediated complex assembly|down regulation of DISC formation|down regulation of death-inducing signalling complex assembly|inhibition of death-inducing signalling complex assembly|inhibition of DISC formation|negative regulation of DISC assembly|down-regulation of DISC assembly|down-regulation of death-inducing signaling complex assembly|downregulation of DD-mediated complex assembly|inhibition of DISC assembly|down regulation of DD-mediated complex assembly|negative regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down-regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|inhibition of DD-mediated complex assembly|inhibition of death-inducing signaling complex assembly|negative regulation of death domain-mediated complex assembly|down-regulation of death domain-mediated complex assembly|down-regulation of death-inducing signaling complex formation|negative regulation of death-inducing signaling complex formation|down-regulation of DISC formation|down-regulation of death-inducing signalling complex assembly|negative regulation of DISC formation|negative regulation of death-inducing signalling complex assembly|downregulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of DISC assembly|downregulation of death domain-mediated complex assembly|downregulation of death-inducing signaling complex formation http://purl.obolibrary.org/obo/GO_1903073 GO:1903072 biolink:BiologicalProcess regulation of death-inducing signaling complex assembly Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly. go-plus.json regulation of death-inducing signaling complex formation|regulation of death-inducing signalling complex assembly|regulation of DISC formation|regulation of DD-mediated complex assembly|regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|regulation of DISC assembly|regulation of death domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_1903072 GO:1903071 biolink:BiologicalProcess positive regulation of ER-associated ubiquitin-dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. go-plus.json upregulation of ER-associated protein breakdown|up regulation of endoplasmic reticulum-associated protein catabolic process|upregulation of ER-associated ubiquitin-dependent protein catabolic process|upregulation of endoplasmic reticulum-associated protein catabolism|upregulation of ER-associated protein catabolic process|up regulation of ER-associated protein degradation|up-regulation of ERAD|activation of ER-associated protein degradation|positive regulation of ER-associated protein degradation|upregulation of ER-associated protein catabolism|activation of ERAD|up regulation of ER-associated protein breakdown|upregulation of endoplasmic reticulum-associated protein catabolic process|positive regulation of ER-associated protein breakdown|activation of ER-associated protein breakdown|up regulation of ER-associated ubiquitin-dependent protein catabolic process|up regulation of endoplasmic reticulum-associated protein catabolism|positive regulation of endoplasmic reticulum-associated protein catabolism|activation of ER-associated ubiquitin-dependent protein catabolic process|up regulation of ER-associated protein catabolic process|activation of endoplasmic reticulum-associated protein catabolism|positive regulation of ER-associated protein catabolic process|activation of ER-associated protein catabolic process|up-regulation of ER-associated protein catabolism|activation of ER-associated protein catabolism|positive regulation of ERAD|up-regulation of ER-associated protein degradation|up-regulation of endoplasmic reticulum-associated protein catabolic process|activation of endoplasmic reticulum-associated protein catabolic process|up regulation of ERAD|up-regulation of ER-associated protein breakdown|up-regulation of endoplasmic reticulum-associated protein catabolism|up-regulation of ER-associated ubiquitin-dependent protein catabolic process|up-regulation of ER-associated protein catabolic process|upregulation of ER-associated protein degradation|positive regulation of ER-associated protein catabolism|positive regulation of endoplasmic reticulum-associated protein catabolic process|up regulation of ER-associated protein catabolism|upregulation of ERAD http://purl.obolibrary.org/obo/GO_1903071 GO:1903070 biolink:BiologicalProcess negative regulation of ER-associated ubiquitin-dependent protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. go-plus.json downregulation of ER-associated protein catabolism|downregulation of ER-associated protein degradation|down regulation of ER-associated protein breakdown|downregulation of endoplasmic reticulum-associated protein catabolic process|down regulation of ER-associated ubiquitin-dependent protein catabolic process|down regulation of ER-associated protein catabolism|down regulation of endoplasmic reticulum-associated protein catabolism|inhibition of ER-associated protein catabolism|down regulation of ER-associated protein catabolic process|down regulation of endoplasmic reticulum-associated protein catabolic process|downregulation of ER-associated protein breakdown|inhibition of endoplasmic reticulum-associated protein catabolic process|downregulation of ER-associated ubiquitin-dependent protein catabolic process|downregulation of endoplasmic reticulum-associated protein catabolism|negative regulation of ER-associated protein degradation|down-regulation of ER-associated protein degradation|downregulation of ER-associated protein catabolic process|down-regulation of ERAD|negative regulation of ERAD|down-regulation of ER-associated protein breakdown|negative regulation of ER-associated protein breakdown|inhibition of ER-associated protein degradation|negative regulation of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated ubiquitin-dependent protein catabolic process|down-regulation of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated protein catabolic process|negative regulation of ER-associated protein catabolic process|inhibition of ER-associated protein breakdown|downregulation of ERAD|inhibition of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated protein catabolism|negative regulation of ER-associated protein catabolism|inhibition of ER-associated ubiquitin-dependent protein catabolic process|inhibition of ER-associated protein catabolic process|down-regulation of endoplasmic reticulum-associated protein catabolic process|negative regulation of endoplasmic reticulum-associated protein catabolic process|down regulation of ERAD|inhibition of ERAD|down regulation of ER-associated protein degradation http://purl.obolibrary.org/obo/GO_1903070 GO:1903079 biolink:BiologicalProcess obsolete negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape OBSOLETE. Any negative regulation of protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape. go-plus.json down-regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down-regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_1903079 GO:1903089 biolink:MolecularActivity 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other. go-plus.json acadesine transporter activity http://purl.obolibrary.org/obo/GO_1903089 GO:1903088 biolink:BiologicalProcess 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903088 GO:1903087 biolink:BiologicalProcess mitotic spindle pole body duplication Any spindle pole body duplication that is involved in the mitotic cell cycle. go-plus.json spindle pole body biosynthesis involved in mitotic cell cycle|spindle pole body replication involved in mitotic cell cycle|spindle pole body formation involved in mitotic cell cycle|spindle pole body duplication associated with nuclear envelope involved in mitotic cell cycle|spindle pole body biogenesis involved in mitotic cell cycle|spindle pole body duplication in cytoplasm involved in mitotic cell cycle|spindle pole body assembly involved in mitotic cell cycle|spindle pole body duplication involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1903087 GO:1903086 biolink:BiologicalProcess negative regulation of sinapate ester biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis. go-plus.json downregulation of sinapate ester anabolism|inhibition of sinapate ester biosynthesis|inhibition of sinapate ester biosynthetic process|downregulation of sinapate ester synthesis|down regulation of sinapate ester anabolism|inhibition of sinapate ester anabolism|downregulation of sinapate ester formation|down regulation of sinapate ester synthesis|inhibition of sinapate ester synthesis|down regulation of sinapate ester formation|inhibition of sinapate ester formation|down regulation of sinapate ester biosynthetic process|down regulation of sinapate ester biosynthesis|downregulation of sinapate ester biosynthesis|downregulation of sinapate ester biosynthetic process|down-regulation of sinapate ester anabolism|negative regulation of sinapate ester anabolism|down-regulation of sinapate ester synthesis|negative regulation of sinapate ester biosynthesis|down-regulation of sinapate ester biosynthetic process|negative regulation of sinapate ester synthesis|down-regulation of sinapate ester biosynthesis|down-regulation of sinapate ester formation|negative regulation of sinapate ester formation http://purl.obolibrary.org/obo/GO_1903086 GO:1903085 biolink:BiologicalProcess regulation of sinapate ester biosynthetic process Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis. go-plus.json regulation of sinapate ester anabolism|regulation of sinapate ester synthesis|regulation of sinapate ester formation|regulation of sinapate ester biosynthesis http://purl.obolibrary.org/obo/GO_1903085 GO:1903084 biolink:BiologicalProcess protein localization to condensed nuclear chromosome A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome. go-plus.json protein localisation in condensed nuclear chromosome|protein localization in condensed nuclear chromosome|protein localisation to condensed nuclear chromosome http://purl.obolibrary.org/obo/GO_1903084 GO:1903083 biolink:BiologicalProcess protein localization to condensed chromosome A process in which a protein is transported to, or maintained in, a location within a condensed chromosome. go-plus.json protein localisation in condensed chromosome|protein localization in condensed chromosome|protein localisation to condensed chromosome http://purl.obolibrary.org/obo/GO_1903083 GO:1903082 biolink:BiologicalProcess positive regulation of C-C chemokine receptor CCR7 signaling pathway Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway. go-plus.json up-regulation of CCR7 signaling pathway|positive regulation of C-C chemokine receptor CCR7 signalling pathway|up regulation of C-C chemokine receptor CCR7 signalling pathway|up regulation of C-C chemokine receptor CCR7 signaling pathway|activation of CCR7 signaling pathway|activation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of CCR7 signaling pathway|up regulation of CCR7 signaling pathway|upregulation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of C-C chemokine receptor CCR7 signaling pathway|activation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of C-C chemokine receptor CCR7 signalling pathway|upregulation of CCR7 signaling pathway|upregulation of C-C chemokine receptor CCR7 signaling pathway http://purl.obolibrary.org/obo/GO_1903082 GO:1903081 biolink:BiologicalProcess negative regulation of C-C chemokine receptor CCR7 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway. go-plus.json downregulation of C-C chemokine receptor CCR7 signaling pathway|downregulation of C-C chemokine receptor CCR7 signalling pathway|negative regulation of CCR7 signaling pathway|down-regulation of CCR7 signaling pathway|down regulation of C-C chemokine receptor CCR7 signalling pathway|down-regulation of C-C chemokine receptor CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signalling pathway|downregulation of CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signaling pathway|down regulation of CCR7 signaling pathway|inhibition of CCR7 signaling pathway|down-regulation of C-C chemokine receptor CCR7 signalling pathway|negative regulation of C-C chemokine receptor CCR7 signalling pathway|down regulation of C-C chemokine receptor CCR7 signaling pathway http://purl.obolibrary.org/obo/GO_1903081 GO:1903080 biolink:BiologicalProcess regulation of C-C chemokine receptor CCR7 signaling pathway Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway. go-plus.json regulation of C-C chemokine receptor CCR7 signalling pathway|regulation of CCR7 signaling pathway http://purl.obolibrary.org/obo/GO_1903080 GO:1903099 biolink:BiologicalProcess positive regulation of CENP-A containing nucleosome assembly Any process that activates or increases the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. go-plus.json up regulation of centromere specific nucleosome exchange|upregulation of centromere-specific nucleosome assembly|up-regulation of CenH3-containing nucleosome assembly at centromere|positive regulation of centromere specific nucleosome exchange|upregulation of DNA replication-independent nucleosome assembly at centromere|up regulation of CENP-A deposition|activation of centromere-specific histone exchange|up-regulation of centromere-specific histone exchange|up-regulation of CENP-A loading|positive regulation of CENP-A deposition|up regulation of CENP-A containing nucleosome assembly at centromere|activation of CenH3-containing nucleosome assembly at centromere|activation of centromere specific nucleosome exchange|activation of CENP-A containing nucleosome assembly at centromere|up-regulation of centromeric DNA replication-independent nucleosome assembly|up regulation of centromere-specific nucleosome assembly|activation of CENP-A loading|activation of CENP-A deposition|activation of centromere-specific nucleosome assembly|positive regulation of CenH3-containing nucleosome assembly at centromere|up-regulation of centromere specific nucleosome exchange|up regulation of DNA replication-independent nucleosome assembly at centromere|positive regulation of centromere-specific nucleosome assembly|activation of DNA replication-independent nucleosome assembly at centromere|up regulation of CenH3-containing nucleosome assembly at centromere|positive regulation of DNA replication-independent nucleosome assembly at centromere|positive regulation of centromere-specific histone exchange|positive regulation of CENP-A loading|upregulation of centromeric DNA replication-independent nucleosome assembly|up-regulation of CENP-A deposition|up regulation of centromere-specific histone exchange|up regulation of CENP-A loading|up-regulation of CENP-A containing nucleosome assembly at centromere|upregulation of centromere specific nucleosome exchange|up-regulation of centromere-specific nucleosome assembly|upregulation of CenH3-containing nucleosome assembly at centromere|up-regulation of DNA replication-independent nucleosome assembly at centromere|upregulation of CENP-A deposition|up regulation of centromeric DNA replication-independent nucleosome assembly|activation of centromeric DNA replication-independent nucleosome assembly|upregulation of centromere-specific histone exchange|positive regulation of centromeric DNA replication-independent nucleosome assembly|upregulation of CENP-A loading|upregulation of CENP-A containing nucleosome assembly at centromere http://purl.obolibrary.org/obo/GO_1903099 GO:1903098 biolink:BiologicalProcess negative regulation of CENP-A containing nucleosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. go-plus.json down regulation of CENP-A containing nucleosome assembly at centromere|negative regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of CENP-A loading|down-regulation of centromeric DNA replication-independent nucleosome assembly|downregulation of CENP-A deposition|downregulation of CENP-A containing nucleosome assembly at centromere|down regulation of centromere-specific nucleosome assembly|down regulation of DNA replication-independent nucleosome assembly at centromere|down-regulation of centromere specific nucleosome exchange|negative regulation of centromere specific nucleosome exchange|down-regulation of CenH3-containing nucleosome assembly at centromere|negative regulation of CenH3-containing nucleosome assembly at centromere|inhibition of centromeric DNA replication-independent nucleosome assembly|downregulation of centromere-specific nucleosome assembly|downregulation of DNA replication-independent nucleosome assembly at centromere|negative regulation of CENP-A deposition|down-regulation of CENP-A deposition|down-regulation of centromere-specific histone exchange|negative regulation of centromere-specific histone exchange|down-regulation of CENP-A loading|negative regulation of CENP-A loading|down-regulation of CENP-A containing nucleosome assembly at centromere|downregulation of CenH3-containing nucleosome assembly at centromere|down-regulation of centromere-specific nucleosome assembly|negative regulation of centromere-specific nucleosome assembly|inhibition of centromere specific nucleosome exchange|down-regulation of DNA replication-independent nucleosome assembly at centromere|negative regulation of DNA replication-independent nucleosome assembly at centromere|down regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of CENP-A containing nucleosome assembly at centromere|down regulation of CenH3-containing nucleosome assembly at centromere|downregulation of centromere-specific histone exchange|downregulation of CENP-A loading|inhibition of CENP-A deposition|downregulation of centromeric DNA replication-independent nucleosome assembly|inhibition of centromere-specific nucleosome assembly|down regulation of centromere-specific histone exchange|down regulation of centromere specific nucleosome exchange|inhibition of DNA replication-independent nucleosome assembly at centromere|down regulation of CENP-A loading|inhibition of centromere-specific histone exchange|inhibition of CenH3-containing nucleosome assembly at centromere|downregulation of centromere specific nucleosome exchange|down regulation of CENP-A deposition http://purl.obolibrary.org/obo/GO_1903098 GO:1903097 biolink:BiologicalProcess regulation of CENP-A containing nucleosome assembly Any process that modulates the rate, frequency or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. go-plus.json regulation of CENP-A deposition|regulation of centromere-specific nucleosome assembly|regulation of DNA replication-independent nucleosome assembly at centromere|regulation of CenH3-containing nucleosome assembly at centromere|regulation of centromeric DNA replication-independent nucleosome assembly|regulation of centromere-specific histone exchange|regulation of CENP-A loading|regulation of centromere specific nucleosome exchange http://purl.obolibrary.org/obo/GO_1903097 GO:1903096 biolink:BiologicalProcess protein localization to meiotic spindle midzone A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone. go-plus.json protein localization in meiotic spindle midzone|protein localisation in meiotic spindle midzone|protein localisation to meiotic spindle midzone http://purl.obolibrary.org/obo/GO_1903096 GO:1903095 biolink:CellularComponent ribonuclease III complex A protein complex which is capable of ribonuclease III activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903095 GO:1903094 biolink:BiologicalProcess negative regulation of protein K48-linked deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination. go-plus.json down-regulation of protein K48-linked deubiquitination|inhibition of protein K48-linked deubiquitination|down regulation of protein K48-linked deubiquitination|downregulation of protein K48-linked deubiquitination http://purl.obolibrary.org/obo/GO_1903094 GO:1903093 biolink:BiologicalProcess regulation of protein K48-linked deubiquitination Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_1903093 GO:1903092 biolink:BiologicalProcess pyridoxine transmembrane transport The process in which pyridoxine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903092 GO:1903091 biolink:BiologicalProcess pyridoxamine transmembrane transport The process in which pyridoxamine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903091 GO:1903090 biolink:BiologicalProcess pyridoxal transmembrane transport The process in which pyridoxal is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1903090 UBERON:0035881 biolink:AnatomicalEntity ethmoidomaxillary suture A suture between the orbital surface of the body of the maxilla with the orbital plate of the ethmoid bone. go-plus.json ethmoidomaxillary suture of skull|sutura ethmoidomaxillaris http://purl.obolibrary.org/obo/UBERON_0035881 UBERON:0035882 biolink:AnatomicalEntity sphenomaxillary suture an inconstant suture between the pterygoid process of the sphenoid bone and the body of the maxilla. go-plus.json sutura sphenomaxillaris|sphenomaxillary suture of skull http://purl.obolibrary.org/obo/UBERON_0035882 UBERON:0035884 biolink:AnatomicalEntity maxillary-premaxillary suture A suture between the maxilla and premaxilla. go-plus.json premaxillary suture|maxillary-premaxillary incisive suture|incisive suture http://purl.obolibrary.org/obo/UBERON_0035884 CHEBI:133084 biolink:ChemicalSubstance prostaglandin G1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133084 chebi_ph7_3 CHEBI:53406 biolink:ChemicalSubstance cis-1,4-polyisoprene go-plus.json http://purl.obolibrary.org/obo/CHEBI_53406 chebi_ph7_3 CHEBI:28446 biolink:ChemicalSubstance 3D-3,5/4-trihydroxycyclohexane-1,2-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_28446 chebi_ph7_3 CHEBI:53405 biolink:ChemicalSubstance poly(isoprene) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53405 chebi_ph7_3 CHEBI:53404 biolink:ChemicalSubstance poly(alkylene vinylene) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53404 chebi_ph7_3 CHEBI:28442 biolink:ChemicalSubstance 15-oxoprostaglandin F2alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_28442 UBERON:0011871 biolink:AnatomicalEntity nasomaxillary suture A cranial suture that connects a nasal bone and connects a maxilla. go-plus.json articulation of the nasal bone with maxilla|nasomaxillary suture of skull http://purl.obolibrary.org/obo/UBERON_0011871 UBERON:0011865 biolink:AnatomicalEntity corneal stroma collagen fibril The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity go-plus.json http://purl.obolibrary.org/obo/UBERON_0011865 UBERON:0011864 biolink:AnatomicalEntity tendon collagen fibril The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity go-plus.json http://purl.obolibrary.org/obo/UBERON_0011864 CHEBI:28459 biolink:ChemicalSubstance D-alpha-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28459 CHEBI:28453 biolink:ChemicalSubstance (20S)-20-hydroxypregn-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28453 chebi_ph7_3 CHEBI:28455 biolink:ChemicalSubstance D-arabinitol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28455 UBERON:0011863 biolink:AnatomicalEntity bone collagen fibril The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity go-plus.json http://purl.obolibrary.org/obo/UBERON_0011863 UBERON:0011862 biolink:AnatomicalEntity pulmonary collagen fibril The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity go-plus.json http://purl.obolibrary.org/obo/UBERON_0011862 UBERON:0011861 biolink:AnatomicalEntity aorta collagen fibril The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity go-plus.json http://purl.obolibrary.org/obo/UBERON_0011861 UBERON:0011860 biolink:AnatomicalEntity collection of collagen fibrils go-plus.json http://purl.obolibrary.org/obo/UBERON_0011860 GO:1903001 biolink:BiologicalProcess negative regulation of lipid transport across blood-brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier. go-plus.json down-regulation of lipid transport across blood brain barrier|downregulation of lipid transport across blood brain barrier|down regulation of lipid transport across blood brain barrier|inhibition of lipid transport across blood brain barrier|negative regulation of lipid transport across blood brain barrier http://purl.obolibrary.org/obo/GO_1903001 UBERON:0011856 biolink:AnatomicalEntity acinus of lactiferous gland An acinus that is part of a mammary gland. go-plus.json lactiferous gland acinus http://purl.obolibrary.org/obo/UBERON_0011856 GO:1903000 biolink:BiologicalProcess regulation of lipid transport across blood-brain barrier Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier. go-plus.json regulation of lipid transport across blood brain barrier http://purl.obolibrary.org/obo/GO_1903000 UBERON:0011858 biolink:AnatomicalEntity acinus of exocrine gland An acinus that is part of a exocrine gland. go-plus.json exocrine gland acinus http://purl.obolibrary.org/obo/UBERON_0011858 UBERON:0011857 biolink:AnatomicalEntity acinus of lacrimal gland An acinus that is part of a lacrimal gland. go-plus.json lacrimal gland acinus http://purl.obolibrary.org/obo/UBERON_0011857 CHEBI:28428 biolink:ChemicalSubstance beta-hexachlorocyclohexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_28428 chebi_ph7_3 CHEBI:28425 biolink:ChemicalSubstance alpha-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28425 chebi_ph7_3 CHEBI:28424 biolink:ChemicalSubstance alpha-Neu5NAc-(2->8)-alpha-Neu5NAc-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_28424 CHEBI:28427 biolink:ChemicalSubstance arabinoxylan go-plus.json http://purl.obolibrary.org/obo/CHEBI_28427 CHEBI:28426 biolink:ChemicalSubstance cyanidin 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28426 GO:1903009 biolink:BiologicalProcess proteasome complex disassembly The disaggregation of a proteasome complex into its constituent components. go-plus.json proteasome degradation|proteasome disassembly|26S proteasome disassembly http://purl.obolibrary.org/obo/GO_1903009 GO:1903008 biolink:BiologicalProcess organelle disassembly The disaggregation of an organelle into its constituent components. go-plus.json organelle degradation http://purl.obolibrary.org/obo/GO_1903008 CHEBI:28423 biolink:ChemicalSubstance 6-methoxy-2-octaprenyl-1,4-benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28423 chebi_ph7_3 GO:1903007 biolink:BiologicalProcess positive regulation of Lys63-specific deubiquitinase activity Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity. go-plus.json upregulation of Lys63-specific deubiquitinase activity|up-regulation of Lys63-specific deubiquitinase activity|activation of Lys63-specific deubiquitinase activity|up regulation of Lys63-specific deubiquitinase activity http://purl.obolibrary.org/obo/GO_1903007 GO:1903006 biolink:BiologicalProcess positive regulation of protein K63-linked deubiquitination Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination. go-plus.json up regulation of protein K63-linked deubiquitination|activation of protein K63-linked deubiquitination|up-regulation of protein K63-linked deubiquitination|upregulation of protein K63-linked deubiquitination http://purl.obolibrary.org/obo/GO_1903006 CHEBI:28422 biolink:ChemicalSubstance 3-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28422 GO:1903005 biolink:BiologicalProcess negative regulation of protein K63-linked deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination. go-plus.json down regulation of protein K63-linked deubiquitination|downregulation of protein K63-linked deubiquitination|down-regulation of protein K63-linked deubiquitination|inhibition of protein K63-linked deubiquitination http://purl.obolibrary.org/obo/GO_1903005 GO:1903004 biolink:BiologicalProcess regulation of protein K63-linked deubiquitination Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination. go-plus.json http://purl.obolibrary.org/obo/GO_1903004 GO:1903003 biolink:BiologicalProcess positive regulation of protein deubiquitination Any process that activates or increases the frequency, rate or extent of protein deubiquitination. go-plus.json up-regulation of protein deubiquitylation|activation of protein deubiquitylation|up-regulation of protein deubiquitinylation|upregulation of deubiquitination|activation of protein deubiquitinylation|upregulation of protein deubiquitination|positive regulation of protein deubiquitylation|up regulation of protein deubiquitylation|up-regulation of deubiquitination|positive regulation of protein deubiquitinylation|activation of deubiquitination|up-regulation of protein deubiquitination|up regulation of protein deubiquitinylation|activation of protein deubiquitination|upregulation of protein deubiquitylation|positive regulation of deubiquitination|upregulation of protein deubiquitinylation|up regulation of deubiquitination|up regulation of protein deubiquitination http://purl.obolibrary.org/obo/GO_1903003 UBERON:0011850 biolink:AnatomicalEntity acinus of salivary gland An acinus that is part of a salivary gland. go-plus.json salivary gland acinus http://purl.obolibrary.org/obo/UBERON_0011850 GO:1903002 biolink:BiologicalProcess positive regulation of lipid transport across blood-brain barrier Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier. go-plus.json positive regulation of lipid transport across blood brain barrier|activation of lipid transport across blood brain barrier|up-regulation of lipid transport across blood brain barrier|up regulation of lipid transport across blood brain barrier|upregulation of lipid transport across blood brain barrier http://purl.obolibrary.org/obo/GO_1903002 GO:1903012 biolink:BiologicalProcess positive regulation of bone development Any process that activates or increases the frequency, rate or extent of bone development. go-plus.json up-regulation of bone development|activation of bone development|up regulation of bone development|upregulation of bone development http://purl.obolibrary.org/obo/GO_1903012 UBERON:0011845 biolink:AnatomicalEntity duct of sebaceous gland A duct that is part of a sebaceous gland. go-plus.json sebaceous gland duct http://purl.obolibrary.org/obo/UBERON_0011845 GO:1903011 biolink:BiologicalProcess negative regulation of bone development Any process that stops, prevents or reduces the frequency, rate or extent of bone development. go-plus.json down-regulation of bone development|downregulation of bone development|down regulation of bone development|inhibition of bone development http://purl.obolibrary.org/obo/GO_1903011 GO:1903010 biolink:BiologicalProcess regulation of bone development Any process that modulates the frequency, rate or extent of bone development. go-plus.json http://purl.obolibrary.org/obo/GO_1903010 UBERON:0011846 biolink:AnatomicalEntity acinus of sebaceous gland An acinus that is part of a sebaceous gland. go-plus.json sebaceous gland acinus http://purl.obolibrary.org/obo/UBERON_0011846 CHEBI:7203 biolink:ChemicalSubstance N-acetylhexosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_7203 chebi_ph7_3 CHEBI:28436 biolink:ChemicalSubstance delphinidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28436 GO:1903019 biolink:BiologicalProcess negative regulation of glycoprotein metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. go-plus.json down-regulation of glycoprotein metabolism|negative regulation of glycoprotein metabolism|down-regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolism|downregulation of glycoprotein metabolic process|down regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolic process|down regulation of glycoprotein metabolism|downregulation of glycoprotein metabolism http://purl.obolibrary.org/obo/GO_1903019 GO:1903018 biolink:BiologicalProcess regulation of glycoprotein metabolic process Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. go-plus.json regulation of glycoprotein metabolism http://purl.obolibrary.org/obo/GO_1903018 GO:1903017 biolink:BiologicalProcess positive regulation of exo-alpha-sialidase activity Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity. go-plus.json upregulation of neuraminidase activity|upregulation of exo-alpha-sialidase activity|upregulation of sialidase activity|positive regulation of alpha-neuraminidase activity|up-regulation of acetylneuraminidase activity|activation of acetylneuraminidase activity|up regulation of acetylneuraminyl hydrolase activity|upregulation of N-acylneuraminate glycohydrolase activity|up regulation of alpha-neuraminidase activity|activation of acetylneuraminyl hydrolase activity|positive regulation of acetylneuraminyl hydrolase activity|up-regulation of neuraminidase activity|activation of neuraminidase activity|up-regulation of exo-alpha-sialidase activity|up-regulation of sialidase activity|activation of sialidase activity|activation of exo-alpha-sialidase activity|positive regulation of acetylneuraminidase activity|upregulation of alpha-neuraminidase activity|up regulation of N-acylneuraminate glycohydrolase activity|up regulation of acetylneuraminidase activity|activation of N-acylneuraminate glycohydrolase activity|up-regulation of acetylneuraminyl hydrolase activity|positive regulation of N-acylneuraminate glycohydrolase activity|positive regulation of neuraminidase activity|up regulation of neuraminidase activity|positive regulation of sialidase activity|up-regulation of alpha-neuraminidase activity|up regulation of exo-alpha-sialidase activity|up regulation of sialidase activity|activation of alpha-neuraminidase activity|upregulation of acetylneuraminidase activity|upregulation of acetylneuraminyl hydrolase activity|up-regulation of N-acylneuraminate glycohydrolase activity http://purl.obolibrary.org/obo/GO_1903017 CHEBI:28433 biolink:ChemicalSubstance phyllohydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_28433 chebi_ph7_3 GO:1903016 biolink:BiologicalProcess negative regulation of exo-alpha-sialidase activity Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity. go-plus.json negative regulation of alpha-neuraminidase activity|down regulation of exo-alpha-sialidase activity|down-regulation of alpha-neuraminidase activity|down regulation of sialidase activity|inhibition of exo-alpha-sialidase activity|inhibition of sialidase activity|downregulation of acetylneuraminyl hydrolase activity|down regulation of N-acylneuraminate glycohydrolase activity|downregulation of alpha-neuraminidase activity|negative regulation of acetylneuraminidase activity|down-regulation of acetylneuraminidase activity|negative regulation of acetylneuraminyl hydrolase activity|down-regulation of acetylneuraminyl hydrolase activity|downregulation of N-acylneuraminate glycohydrolase activity|down regulation of alpha-neuraminidase activity|inhibition of alpha-neuraminidase activity|negative regulation of neuraminidase activity|down-regulation of neuraminidase activity|inhibition of acetylneuraminyl hydrolase activity|negative regulation of sialidase activity|down-regulation of exo-alpha-sialidase activity|down-regulation of sialidase activity|downregulation of acetylneuraminidase activity|negative regulation of N-acylneuraminate glycohydrolase activity|down-regulation of N-acylneuraminate glycohydrolase activity|downregulation of neuraminidase activity|down regulation of acetylneuraminidase activity|inhibition of acetylneuraminidase activity|downregulation of exo-alpha-sialidase activity|downregulation of sialidase activity|inhibition of N-acylneuraminate glycohydrolase activity|down regulation of neuraminidase activity|inhibition of neuraminidase activity|down regulation of acetylneuraminyl hydrolase activity http://purl.obolibrary.org/obo/GO_1903016 GO:1903015 biolink:BiologicalProcess regulation of exo-alpha-sialidase activity Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity. go-plus.json regulation of acetylneuraminyl hydrolase activity|regulation of alpha-neuraminidase activity|regulation of N-acylneuraminate glycohydrolase activity|regulation of acetylneuraminidase activity|regulation of neuraminidase activity|regulation of sialidase activity http://purl.obolibrary.org/obo/GO_1903015 GO:1903014 biolink:BiologicalProcess cellular response to differentiation-inducing factor 1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus. go-plus.json cellular response to DIF1|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one|cellular response to DIF-1|DIF-1 http://purl.obolibrary.org/obo/GO_1903014 GO:1903013 biolink:BiologicalProcess response to differentiation-inducing factor 1 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus. go-plus.json response to DIF1|DIF-1|response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one|response to DIF-1 http://purl.obolibrary.org/obo/GO_1903013 GO:1903023 biolink:BiologicalProcess regulation of ascospore-type prospore membrane formation Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane. go-plus.json regulation of forespore membrane biosynthesis|regulation of forespore membrane formation|regulation of ascospore-type prospore membrane assembly|regulation of FSM biosynthesis|regulation of FSM formation|regulation of FSM assembly http://purl.obolibrary.org/obo/GO_1903023 GO:1903022 biolink:BiologicalProcess positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands. go-plus.json upregulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up-regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|activation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands http://purl.obolibrary.org/obo/GO_1903022 GO:1903021 biolink:BiologicalProcess regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands. go-plus.json http://purl.obolibrary.org/obo/GO_1903021 GO:1903020 biolink:BiologicalProcess positive regulation of glycoprotein metabolic process Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. go-plus.json upregulation of glycoprotein metabolic process|up regulation of glycoprotein metabolism|activation of glycoprotein metabolism|positive regulation of glycoprotein metabolism|up-regulation of glycoprotein metabolic process|activation of glycoprotein metabolic process|up-regulation of glycoprotein metabolism|up regulation of glycoprotein metabolic process|upregulation of glycoprotein metabolism http://purl.obolibrary.org/obo/GO_1903020 CHEBI:28408 biolink:ChemicalSubstance 4-de(dimethylamino)-4-oxoanhydrotetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28408 CHEBI:28401 biolink:ChemicalSubstance N-acetyl-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_28401 chebi_ph7_3 GO:1903028 biolink:BiologicalProcess positive regulation of opsonization Any process that activates or increases the frequency, rate or extent of opsonization. go-plus.json activation of opsonization|up-regulation of opsonization|up regulation of opsonization|upregulation of opsonization http://purl.obolibrary.org/obo/GO_1903028 GO:1903027 biolink:BiologicalProcess regulation of opsonization Any process that modulates the frequency, rate or extent of opsonization. go-plus.json http://purl.obolibrary.org/obo/GO_1903027 GO:1903026 biolink:BiologicalProcess negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. go-plus.json down-regulation of RNA polymerase II regulatory region sequence-specific DNA binding|inhibition of RNA polymerase II regulatory region sequence-specific DNA binding|down regulation of RNA polymerase II regulatory region sequence-specific DNA binding|downregulation of RNA polymerase II regulatory region sequence-specific DNA binding http://purl.obolibrary.org/obo/GO_1903026 GO:1903025 biolink:BiologicalProcess regulation of RNA polymerase II regulatory region sequence-specific DNA binding Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. go-plus.json http://purl.obolibrary.org/obo/GO_1903025 GO:1903024 biolink:BiologicalProcess positive regulation of ascospore-type prospore membrane formation Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane. go-plus.json activation of FSM formation|positive regulation of FSM formation|positive regulation of forespore membrane formation|upregulation of forespore membrane biosynthesis|upregulation of FSM assembly|up regulation of ascospore-type prospore membrane assembly|up regulation of forespore membrane formation|activation of ascospore-type prospore membrane assembly|up-regulation of FSM biosynthesis|activation of FSM biosynthesis|up-regulation of FSM formation|up-regulation of FSM assembly|activation of FSM assembly|up regulation of forespore membrane biosynthesis|upregulation of forespore membrane formation|activation of forespore membrane biosynthesis|positive regulation of forespore membrane biosynthesis|up-regulation of ascospore-type prospore membrane assembly|positive regulation of FSM biosynthesis|up regulation of FSM biosynthesis|upregulation of FSM formation|positive regulation of FSM assembly|up-regulation of forespore membrane formation|activation of forespore membrane formation|up regulation of FSM assembly|up-regulation of forespore membrane biosynthesis|upregulation of ascospore-type prospore membrane assembly|positive regulation of ascospore-type prospore membrane assembly|upregulation of FSM biosynthesis|up regulation of FSM formation http://purl.obolibrary.org/obo/GO_1903024 GO:1903034 biolink:BiologicalProcess regulation of response to wounding Any process that modulates the frequency, rate or extent of response to wounding. go-plus.json regulation of physiological response to wounding http://purl.obolibrary.org/obo/GO_1903034 GO:1903033 biolink:BiologicalProcess positive regulation of microtubule plus-end binding Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding. go-plus.json up-regulation of microtubule plus-end binding|activation of microtubule plus-end binding|up regulation of microtubule plus-end binding|upregulation of microtubule plus-end binding http://purl.obolibrary.org/obo/GO_1903033 GO:1903032 biolink:BiologicalProcess negative regulation of microtubule plus-end binding Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding. go-plus.json down-regulation of microtubule plus-end binding|downregulation of microtubule plus-end binding|down regulation of microtubule plus-end binding|inhibition of microtubule plus-end binding http://purl.obolibrary.org/obo/GO_1903032 GO:1903031 biolink:BiologicalProcess regulation of microtubule plus-end binding Any process that modulates the frequency, rate or extent of microtubule plus-end binding. go-plus.json http://purl.obolibrary.org/obo/GO_1903031 CHEBI:28417 biolink:ChemicalSubstance gentamycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_28417 CHEBI:28413 biolink:ChemicalSubstance 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28413 CHEBI:28416 biolink:ChemicalSubstance 5-hydroxyimidazole-4-acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28416 GO:1903039 biolink:BiologicalProcess positive regulation of leukocyte cell-cell adhesion Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. go-plus.json up regulation of leukocyte adhesion|up-regulation of leukocyte cell-cell adhesion|activation of leukocyte cell-cell adhesion|up regulation of leukocyte cell adhesion|activation of leukocyte cell adhesion|positive regulation of leukocyte cell adhesion|upregulation of leukocyte adhesion|up regulation of leukocyte cell-cell adhesion|up-regulation of leukocyte cell adhesion|up-regulation of leukocyte adhesion|activation of leukocyte adhesion|upregulation of leukocyte cell-cell adhesion|upregulation of leukocyte cell adhesion|positive regulation of leukocyte adhesion http://purl.obolibrary.org/obo/GO_1903039 GO:1903038 biolink:BiologicalProcess negative regulation of leukocyte cell-cell adhesion Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. go-plus.json downregulation of leukocyte cell adhesion|downregulation of leukocyte adhesion|down-regulation of leukocyte cell-cell adhesion|down regulation of leukocyte adhesion|inhibition of leukocyte adhesion|down-regulation of leukocyte cell adhesion|negative regulation of leukocyte cell adhesion|downregulation of leukocyte cell-cell adhesion|inhibition of leukocyte cell adhesion|down regulation of leukocyte cell-cell adhesion|inhibition of leukocyte cell-cell adhesion|negative regulation of leukocyte adhesion|down-regulation of leukocyte adhesion|down regulation of leukocyte cell adhesion http://purl.obolibrary.org/obo/GO_1903038 GO:1903037 biolink:BiologicalProcess regulation of leukocyte cell-cell adhesion Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. go-plus.json regulation of leukocyte adhesion|regulation of leukocyte cell adhesion http://purl.obolibrary.org/obo/GO_1903037 GO:1903036 biolink:BiologicalProcess positive regulation of response to wounding Any process that activates or increases the frequency, rate or extent of response to wounding. go-plus.json upregulation of response to wounding|positive regulation of physiological response to wounding|up regulation of physiological response to wounding|up-regulation of response to wounding|activation of response to wounding|upregulation of physiological response to wounding|up regulation of response to wounding|up-regulation of physiological response to wounding|activation of physiological response to wounding http://purl.obolibrary.org/obo/GO_1903036 GO:1903035 biolink:BiologicalProcess negative regulation of response to wounding Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding. go-plus.json inhibition of response to wounding|down-regulation of physiological response to wounding|negative regulation of physiological response to wounding|downregulation of physiological response to wounding|down regulation of physiological response to wounding|inhibition of physiological response to wounding|down-regulation of response to wounding|downregulation of response to wounding|down regulation of response to wounding http://purl.obolibrary.org/obo/GO_1903035 GO:1903045 biolink:BiologicalProcess neural crest cell migration involved in sympathetic nervous system development Any neural crest cell migration that is involved in sympathetic nervous system development. go-plus.json http://purl.obolibrary.org/obo/GO_1903045 GO:1903044 biolink:BiologicalProcess protein localization to membrane raft A process in which a protein is transported to, or maintained in, a location within a membrane raft. go-plus.json protein localisation in membrane raft|protein localisation to membrane raft|protein localization in membrane raft http://purl.obolibrary.org/obo/GO_1903044 UBERON:0011899 biolink:AnatomicalEntity epimysium Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. go-plus.json fascia of muscle organ|epimysia http://purl.obolibrary.org/obo/UBERON_0011899 GO:1903043 biolink:BiologicalProcess positive regulation of chondrocyte hypertrophy Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy. go-plus.json upregulation of chondrocyte hypertrophy|up regulation of chondrocyte hypertrophy|activation of chondrocyte hypertrophy|up-regulation of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_1903043 GO:1903042 biolink:BiologicalProcess negative regulation of chondrocyte hypertrophy Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. go-plus.json down regulation of chondrocyte hypertrophy|downregulation of chondrocyte hypertrophy|down-regulation of chondrocyte hypertrophy|inhibition of chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_1903042 GO:1903041 biolink:BiologicalProcess regulation of chondrocyte hypertrophy Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy. go-plus.json http://purl.obolibrary.org/obo/GO_1903041 UBERON:0035805 biolink:AnatomicalEntity muscle layer of sigmoid colon A muscle layer that is part of the sigmoid colon go-plus.json sigmoid colon muscularis propria|tunica muscularis colon sigmoideum|muscularis externa of sigmoid colon|sigmoideum muscularis|muscularis propria of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0035805 UBERON:0035804 biolink:AnatomicalEntity future mouth The primordial mouth region of the developing head. go-plus.json primordial mouth|primitive mouth http://purl.obolibrary.org/obo/UBERON_0035804 GO:1903040 biolink:BiologicalProcess exon-exon junction complex assembly The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex. go-plus.json EJC formation|EJC assembly|exon-exon junction complex formation http://purl.obolibrary.org/obo/GO_1903040 UBERON:0035809 biolink:AnatomicalEntity serous cavity go-plus.json http://purl.obolibrary.org/obo/UBERON_0035809 CHEBI:7274 biolink:ChemicalSubstance N-formimidoyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7274 UBERON:0011892 biolink:AnatomicalEntity anterior uvea Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris. go-plus.json anterior vascular tunic of the eye|vasculosa oculi|Haller tunica vascula|anterior part of uveal tract|anterior vascular layer of the eyeball|anterior uveal tract|ciliary body and iris|tunica vasculosa bulbosa|ventral uveal tract http://purl.obolibrary.org/obo/UBERON_0011892 GO:1903049 biolink:BiologicalProcess negative regulation of acetylcholine-gated cation channel activity Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity. go-plus.json down regulation of acetylcholine-gated cation channel activity|downregulation of acetylcholine-gated cation channel activity|down-regulation of acetylcholine-gated cation channel activity|inhibition of acetylcholine-gated cation channel activity http://purl.obolibrary.org/obo/GO_1903049 GO:1903048 biolink:BiologicalProcess regulation of acetylcholine-gated cation channel activity Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_1903048 GO:1903047 biolink:BiologicalProcess mitotic cell cycle process A process that is part of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1903047 gocheck_do_not_annotate UBERON:0011894 biolink:AnatomicalEntity lumen of vagina A organ cavity that is part of a vagina. go-plus.json vaginal lumen http://purl.obolibrary.org/obo/UBERON_0011894 GO:1903046 biolink:BiologicalProcess meiotic cell cycle process A process that is part of the meiotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_1903046 goslim_pombe|gocheck_do_not_annotate UBERON:0035820 biolink:AnatomicalEntity peritoneal sac A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity. go-plus.json peritoneal component http://purl.obolibrary.org/obo/UBERON_0035820 GO:1903056 biolink:BiologicalProcess regulation of melanosome organization Any process that modulates the frequency, rate or extent of melanosome organization. go-plus.json regulation of melanosome organization and biogenesis|regulation of melanosome organisation http://purl.obolibrary.org/obo/GO_1903056 GO:1903055 biolink:BiologicalProcess positive regulation of extracellular matrix organization Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. go-plus.json upregulation of extracellular matrix organization|up-regulation of extracellular matrix organization and biogenesis|up regulation of extracellular matrix organisation|activation of extracellular matrix organisation|positive regulation of extracellular matrix organisation|activation of extracellular matrix organization and biogenesis|up regulation of extracellular matrix organization|positive regulation of extracellular matrix organization and biogenesis|activation of extracellular matrix organization|up regulation of extracellular matrix organization and biogenesis|up-regulation of extracellular matrix organisation|up-regulation of extracellular matrix organization|upregulation of extracellular matrix organization and biogenesis|upregulation of extracellular matrix organisation http://purl.obolibrary.org/obo/GO_1903055 GO:1903054 biolink:BiologicalProcess negative regulation of extracellular matrix organization Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. go-plus.json downregulation of extracellular matrix organisation|down regulation of extracellular matrix organization|downregulation of extracellular matrix organization|negative regulation of extracellular matrix organization and biogenesis|down-regulation of extracellular matrix organization and biogenesis|negative regulation of extracellular matrix organisation|down-regulation of extracellular matrix organisation|down-regulation of extracellular matrix organization|inhibition of extracellular matrix organisation|downregulation of extracellular matrix organization and biogenesis|down regulation of extracellular matrix organization and biogenesis|inhibition of extracellular matrix organization|inhibition of extracellular matrix organization and biogenesis|down regulation of extracellular matrix organisation http://purl.obolibrary.org/obo/GO_1903054 UBERON:0035814 biolink:AnatomicalEntity pericardial fat The sum of epicardial and paracardial fat deposits. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035814 GO:1903053 biolink:BiologicalProcess regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of extracellular matrix organization. go-plus.json regulation of extracellular matrix organisation|regulation of extracellular matrix organization and biogenesis http://purl.obolibrary.org/obo/GO_1903053 GO:1903052 biolink:BiologicalProcess positive regulation of proteolysis involved in cellular protein catabolic process Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. go-plus.json up regulation of peptidolysis involved in cellular protein catabolic process|up-regulation of proteolysis during cellular protein catabolic process|activation of proteolysis during cellular protein catabolism|up-regulation of peptidolysis during cellular protein catabolic process|activation of peptidolysis involved in cellular protein catabolic process|positive regulation of peptidolysis involved in cellular protein catabolic process|upregulation of peptidolysis during cellular protein catabolism|upregulation of proteolysis involved in cellular protein catabolic process|up-regulation of peptidolysis involved in cellular protein catabolism|positive regulation of proteolysis during cellular protein catabolism|activation of peptidolysis involved in cellular protein catabolism|activation of peptidolysis during cellular protein catabolic process|up regulation of proteolysis during cellular protein catabolism|upregulation of proteolysis during cellular protein catabolic process|positive regulation of peptidolysis during cellular protein catabolic process|up-regulation of proteolysis involved in cellular protein catabolic process|up-regulation of peptidolysis involved in cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolism|activation of proteolysis involved in cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolic process|positive regulation of peptidolysis during cellular protein catabolism|positive regulation of peptidolysis involved in cellular protein catabolism|upregulation of proteolysis during cellular protein catabolism|up regulation of peptidolysis involved in cellular protein catabolism|up regulation of proteolysis during cellular protein catabolic process|activation of peptidolysis during cellular protein catabolism|upregulation of peptidolysis involved in cellular protein catabolic process|positive regulation of proteolysis during cellular protein catabolic process|upregulation of peptidolysis during cellular protein catabolic process|up regulation of proteolysis involved in cellular protein catabolic process|up-regulation of proteolysis during cellular protein catabolism|activation of proteolysis during cellular protein catabolic process|up-regulation of peptidolysis during cellular protein catabolism|upregulation of peptidolysis involved in cellular protein catabolism http://purl.obolibrary.org/obo/GO_1903052 GO:1903051 biolink:BiologicalProcess negative regulation of proteolysis involved in cellular protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. go-plus.json inhibition of peptidolysis during cellular protein catabolism|down regulation of proteolysis involved in cellular protein catabolic process|inhibition of proteolysis involved in cellular protein catabolic process|negative regulation of proteolysis during cellular protein catabolism|down-regulation of proteolysis during cellular protein catabolism|negative regulation of peptidolysis involved in cellular protein catabolic process|down-regulation of peptidolysis involved in cellular protein catabolic process|inhibition of proteolysis during cellular protein catabolic process|down regulation of peptidolysis during cellular protein catabolism|negative regulation of peptidolysis during cellular protein catabolic process|down-regulation of peptidolysis during cellular protein catabolic process|downregulation of proteolysis during cellular protein catabolism|downregulation of peptidolysis during cellular protein catabolism|down-regulation of peptidolysis involved in cellular protein catabolism|negative regulation of peptidolysis involved in cellular protein catabolism|inhibition of peptidolysis involved in cellular protein catabolic process|down regulation of proteolysis during cellular protein catabolic process|down regulation of proteolysis during cellular protein catabolism|downregulation of proteolysis during cellular protein catabolic process|downregulation of peptidolysis during cellular protein catabolic process|down-regulation of peptidolysis during cellular protein catabolism|negative regulation of peptidolysis during cellular protein catabolism|down-regulation of proteolysis involved in cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolism|down regulation of peptidolysis during cellular protein catabolic process|inhibition of proteolysis during cellular protein catabolism|down regulation of peptidolysis involved in cellular protein catabolism|down regulation of peptidolysis involved in cellular protein catabolic process|inhibition of peptidolysis involved in cellular protein catabolism|negative regulation of proteolysis during cellular protein catabolic process|down-regulation of proteolysis during cellular protein catabolic process|inhibition of peptidolysis during cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolic process|downregulation of proteolysis involved in cellular protein catabolic process http://purl.obolibrary.org/obo/GO_1903051 UBERON:0035815 biolink:AnatomicalEntity paracardial fat Fat deposits in the mediastinum outside the parietal pericardium . go-plus.json intrathoracic fat http://purl.obolibrary.org/obo/UBERON_0035815 GO:1903050 biolink:BiologicalProcess regulation of proteolysis involved in cellular protein catabolic process Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. go-plus.json regulation of peptidolysis during cellular protein catabolism|regulation of proteolysis during cellular protein catabolism|regulation of proteolysis during cellular protein catabolic process|regulation of peptidolysis during cellular protein catabolic process|regulation of peptidolysis involved in cellular protein catabolism|regulation of peptidolysis involved in cellular protein catabolic process http://purl.obolibrary.org/obo/GO_1903050 UBERON:0035818 biolink:AnatomicalEntity visceral fat Any fat deposit surrounding a visceral organ. go-plus.json http://purl.obolibrary.org/obo/UBERON_0035818 UBERON:0035819 biolink:AnatomicalEntity abdominopelvic cavity The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity. go-plus.json cavitas abdominis et pelvis http://purl.obolibrary.org/obo/UBERON_0035819 OBO:cl#has_low_plasma_membrane_amount biolink:OntologyClass has_low_plasma_membrane_amount A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). has_low_plasma_membrane_amount go-plus.json http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount GO:1903059 biolink:BiologicalProcess regulation of protein lipidation Any process that modulates the frequency, rate or extent of protein lipidation. go-plus.json regulation of lipid:protein modification|regulation of protein amino acid lipidation http://purl.obolibrary.org/obo/GO_1903059 GO:1903058 biolink:BiologicalProcess positive regulation of melanosome organization Any process that activates or increases the frequency, rate or extent of melanosome organization. go-plus.json upregulation of melanosome organization|upregulation of melanosome organization and biogenesis|up regulation of melanosome organisation|positive regulation of melanosome organisation|activation of melanosome organisation|up regulation of melanosome organization|up-regulation of melanosome organization and biogenesis|activation of melanosome organization|up-regulation of melanosome organisation|activation of melanosome organization and biogenesis|positive regulation of melanosome organization and biogenesis|up-regulation of melanosome organization|up regulation of melanosome organization and biogenesis|upregulation of melanosome organisation http://purl.obolibrary.org/obo/GO_1903058 GO:1903057 biolink:BiologicalProcess negative regulation of melanosome organization Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization. go-plus.json downregulation of melanosome organisation|down regulation of melanosome organization|inhibition of melanosome organization and biogenesis|downregulation of melanosome organization|down-regulation of melanosome organisation|negative regulation of melanosome organisation|inhibition of melanosome organisation|down-regulation of melanosome organization|down-regulation of melanosome organization and biogenesis|negative regulation of melanosome organization and biogenesis|inhibition of melanosome organization|downregulation of melanosome organization and biogenesis|down regulation of melanosome organisation|down regulation of melanosome organization and biogenesis http://purl.obolibrary.org/obo/GO_1903057 UBERON:0035831 biolink:AnatomicalEntity costal diaphragm The domain of the diaphragm that is a thin domed sheet of muscle composed of a radial array of myofibers extending laterally from the ribs and medially to a central tendon. go-plus.json costal part of diaphragm|pars costalis diaphragmatis http://purl.obolibrary.org/obo/UBERON_0035831 GO:1903067 biolink:BiologicalProcess negative regulation of protein localization to cell tip Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip. go-plus.json down regulation of protein localisation to cell tip|inhibition of protein localisation to cell tip|downregulation of protein localization to cell tip|down regulation of protein localization to cell tip|inhibition of protein localization to cell tip|negative regulation of protein localisation to cell tip|down-regulation of protein localisation to cell tip|down-regulation of protein localization to cell tip|downregulation of protein localisation to cell tip http://purl.obolibrary.org/obo/GO_1903067 UBERON:0011878 biolink:AnatomicalEntity muscle layer of esophagus A muscle layer that is part of a wall of esophagus. go-plus.json tela muscularis (oesophagus)|tunica muscularis oesophageae|muscular layer of oesophagus|muscle coat of esophagus|tunica muscularis esophagi|muscular coat of oesophagus http://purl.obolibrary.org/obo/UBERON_0011878 UBERON:0011877 biolink:AnatomicalEntity margin of tongue The lateral border that separates the dorsum from the inferior surface of the tongue on each side, the two borders meeting anteriorly at the apex.. go-plus.json tongue margin|margo linguae http://purl.obolibrary.org/obo/UBERON_0011877 GO:1903066 biolink:BiologicalProcess regulation of protein localization to cell tip Any process that modulates the frequency, rate or extent of protein localization to cell tip. go-plus.json regulation of protein localisation to cell tip http://purl.obolibrary.org/obo/GO_1903066 UBERON:0035825 biolink:AnatomicalEntity left adrenal gland cortex the thick outer layer of the adrenal gland that is in the left side of the abdomen go-plus.json left adrenal cortex|cortex of left suprarenal gland|cortex of left adrenal gland http://purl.obolibrary.org/obo/UBERON_0035825 GO:1903065 biolink:BiologicalProcess obsolete protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape OBSOLETE. Any protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape. go-plus.json protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape http://purl.obolibrary.org/obo/GO_1903065 GO:1903064 biolink:BiologicalProcess positive regulation of reverse cholesterol transport Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport. go-plus.json upregulation of reverse cholesterol transport|up regulation of reverse cholesterol transport|activation of reverse cholesterol transport|up-regulation of reverse cholesterol transport http://purl.obolibrary.org/obo/GO_1903064 UBERON:0011875 biolink:AnatomicalEntity ligament of sternoclavicular joint A skeletal ligament that is part of a sternoclavicular joint. go-plus.json ligamentum sternoclavicularis|sternoclavicular joint ligament http://purl.obolibrary.org/obo/UBERON_0011875 UBERON:0035827 biolink:AnatomicalEntity right adrenal gland cortex the thick outer layer of the adrenal gland that is in the right side of the abdomen go-plus.json right adrenal cortex|cortex of right suprarenal gland|cortex of right adrenal gland http://purl.obolibrary.org/obo/UBERON_0035827 GO:1903063 biolink:BiologicalProcess negative regulation of reverse cholesterol transport Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport. go-plus.json down regulation of reverse cholesterol transport|downregulation of reverse cholesterol transport|down-regulation of reverse cholesterol transport|inhibition of reverse cholesterol transport http://purl.obolibrary.org/obo/GO_1903063 UBERON:0035826 biolink:AnatomicalEntity left adrenal gland medulla the adrenal gland medulla that is in the left side of the abdomen go-plus.json left adrenal medulla|medulla of left adrenal gland|medulla of left suprarenal gland http://purl.obolibrary.org/obo/UBERON_0035826 GO:1903062 biolink:BiologicalProcess regulation of reverse cholesterol transport Any process that modulates the frequency, rate or extent of reverse cholesterol transport. go-plus.json http://purl.obolibrary.org/obo/GO_1903062 GO:1903061 biolink:BiologicalProcess positive regulation of protein lipidation Any process that activates or increases the frequency, rate or extent of protein lipidation. go-plus.json up-regulation of lipid:protein modification|activation of lipid:protein modification|up-regulation of protein lipidation|activation of protein lipidation|up-regulation of protein amino acid lipidation|positive regulation of lipid:protein modification|upregulation of protein amino acid lipidation|up regulation of lipid:protein modification|up regulation of protein lipidation|up regulation of protein amino acid lipidation|upregulation of lipid:protein modification|upregulation of protein lipidation|positive regulation of protein amino acid lipidation|activation of protein amino acid lipidation http://purl.obolibrary.org/obo/GO_1903061 GO:1903060 biolink:BiologicalProcess negative regulation of protein lipidation Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation. go-plus.json down-regulation of protein amino acid lipidation|negative regulation of protein amino acid lipidation|inhibition of protein amino acid lipidation|negative regulation of lipid:protein modification|down-regulation of lipid:protein modification|down-regulation of protein lipidation|down regulation of protein amino acid lipidation|downregulation of lipid:protein modification|downregulation of protein lipidation|downregulation of protein amino acid lipidation|down regulation of lipid:protein modification|down regulation of protein lipidation|inhibition of lipid:protein modification|inhibition of protein lipidation http://purl.obolibrary.org/obo/GO_1903060 UBERON:0035828 biolink:AnatomicalEntity right adrenal gland medulla the adrenal gland medulla that is in the right side of the abdomen go-plus.json medulla of right suprarenal gland|right adrenal medulla|medulla of right adrenal gland http://purl.obolibrary.org/obo/UBERON_0035828 PR:000015794 biolink:Protein syntaxin-2 A protein that is a translation product of the human STX2 gene or a 1:1 ortholog thereof. go-plus.json STX2|epimorphin|EPIM|STX2C|STX2B|STX2A http://purl.obolibrary.org/obo/PR_000015794 PR:000015795 biolink:Protein syntaxin-3 A protein that is a translation product of the human STX3 gene or a 1:1 ortholog thereof. go-plus.json STX3|STX3A http://purl.obolibrary.org/obo/PR_000015795 PR:000015798 biolink:Protein syntaxin-6 A protein that is a translation product of the human STX6 gene or a 1:1 ortholog thereof. go-plus.json STX6 http://purl.obolibrary.org/obo/PR_000015798 PR:000015797 biolink:Protein syntaxin-5 A protein that is a translation product of the human STX5 gene or a 1:1 ortholog thereof. go-plus.json STX5A|STX5 http://purl.obolibrary.org/obo/PR_000015797 PR:000001150 biolink:Protein tachykinin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human TACR1 to TACR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. These receptors bind tachykinin peptides--neuropeptides of 10-12 amino acids derived from the translation products of the TAC1 and TAC3 genes. Tachykinin receptors are not specific but have different affinities for the various peptides. go-plus.json http://purl.obolibrary.org/obo/PR_000001150 PR:000001141 biolink:Protein interleukin-17D An interleukin-17 that is a translation product of the human IL17D gene or a 1:1 ortholog thereof. go-plus.json IL17D|IL-17D|IL-27|IL27|interleukin-27 http://purl.obolibrary.org/obo/PR_000001141 PR:000001146 biolink:Protein melanocortin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human MC1R to MC5R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds one or more melanocortins, the pituitary peptides ACTH and alpha-, beta-, and gamma-melanocyte-stimulating hormone. go-plus.json http://purl.obolibrary.org/obo/PR_000001146 CHEBI:77332 biolink:ChemicalSubstance saturated fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77332 chebi_ph7_3 CHEBI:77331 biolink:ChemicalSubstance monounsaturated fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77331 chebi_ph7_3 CHEBI:53368 biolink:ChemicalSubstance ionic macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53368 CHEBI:77330 biolink:ChemicalSubstance polyunsaturated fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77330 chebi_ph7_3 CHEBI:77349 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77349 PR:000001153 biolink:Protein Toll-like receptor 2 A Toll-like receptor that is a translation product of the human TLR2 gene or a 1:1 ortholog thereof. go-plus.json CD282|Toll/interleukin-1 receptor-like protein 4|TIL4|TLR2 http://purl.obolibrary.org/obo/PR_000001153 PR:000001155 biolink:Protein Toll-like receptor 4 A Toll-like receptor that is a translation product of the human TLR4 gene or a 1:1 ortholog thereof. go-plus.json CD284|Lps|TLR4|Toll http://purl.obolibrary.org/obo/PR_000001155 CHEBI:133103 biolink:ChemicalSubstance (3alpha,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133103 CHEBI:133105 biolink:ChemicalSubstance (3alpha,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133105 chebi_ph7_3 CHEBI:77344 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77344 CHEBI:77343 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77343 CHEBI:77342 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77342 chebi_ph7_3 CHEBI:77348 biolink:ChemicalSubstance 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77348 CHEBI:77347 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77347 CHEBI:77346 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77346 CHEBI:53353 biolink:ChemicalSubstance GHB receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_53353 CHEBI:77345 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77345 CHEBI:53348 biolink:ChemicalSubstance benzenesulfonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_53348 CHEBI:769 biolink:ChemicalSubstance 16-methoxytabersonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_769 CHEBI:28384 biolink:ChemicalSubstance vitamin K go-plus.json http://purl.obolibrary.org/obo/CHEBI_28384 CHEBI:28383 biolink:ChemicalSubstance alpha,omega-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28383 CHEBI:28386 biolink:ChemicalSubstance 4-hydroxycinnamyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28386 chebi_ph7_3 PR:000001120 biolink:Protein apelin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human APLNR gene or a 1:1 ortholog thereof. The preferred ligand is apelin. go-plus.json APLNR|APJ|G-protein coupled receptor APJ|angiotensin receptor-like 1|MSR|AGTRL1|G-protein coupled receptor HG11 http://purl.obolibrary.org/obo/PR_000001120 CHEBI:28390 biolink:ChemicalSubstance (R)-1-aminopropan-2-yl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28390 CHEBI:28393 biolink:ChemicalSubstance beta-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_28393 PR:000001122 biolink:Protein bombesin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human NMBR, GRPR, or BRS3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds bombesin (a 14 amino acid peptide originally isolated from the skin of a frog) or its homologs. Mammalian homologs of bombesin include gastrin-releasing peptide and neuromedin-B. go-plus.json http://purl.obolibrary.org/obo/PR_000001122 PR:000001121 biolink:Protein beta adrenergic receptor An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that cause activation of adenylate cyclase. go-plus.json http://purl.obolibrary.org/obo/PR_000001121 CHEBI:766 biolink:ChemicalSubstance estriol 16-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_766 CHEBI:77351 biolink:ChemicalSubstance novapikromycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77351 chebi_ph7_3 CHEBI:77350 biolink:ChemicalSubstance neopikromycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77350 chebi_ph7_3 PR:000001123 biolink:Protein bradykinin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human BDKRB1 or BDKRB2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds bradykinin. go-plus.json http://purl.obolibrary.org/obo/PR_000001123 CHEBI:763 biolink:ChemicalSubstance algestone go-plus.json http://purl.obolibrary.org/obo/CHEBI_763 chebi_ph7_3 CHEBI:77355 biolink:ChemicalSubstance 1-palmityl-2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77355 PR:000001128 biolink:Protein chemokine receptor A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines. go-plus.json http://purl.obolibrary.org/obo/PR_000001128 CHEBI:77354 biolink:ChemicalSubstance novamethymycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77354 chebi_ph7_3 CHEBI:77353 biolink:ChemicalSubstance neomethymycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77353 chebi_ph7_3 CHEBI:7285 biolink:ChemicalSubstance N-(D-glucopyranosyl)nicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_7285 CHEBI:77352 biolink:ChemicalSubstance methymycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77352 chebi_ph7_3 CHEBI:77358 biolink:ChemicalSubstance CDP-dipalmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77358 CHEBI:77357 biolink:ChemicalSubstance 1-palmityl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_77357 CHEBI:53339 biolink:ChemicalSubstance olefinic fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53339 CHEBI:53338 biolink:ChemicalSubstance 3-hydroxy-3-methyl-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_53338 chebi_ph7_3 CHEBI:28398 biolink:ChemicalSubstance butan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_28398 chebi_ph7_3 CHEBI:28395 biolink:ChemicalSubstance (+-)-trans-acenaphthene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28395 chebi_ph7_3 CHEBI:28394 biolink:ChemicalSubstance enol-oxaloacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28394 CHEBI:28397 biolink:ChemicalSubstance cis-4-hydroxy-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_28397 CHEBI:28396 biolink:ChemicalSubstance 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_28396 chebi_ph7_3 PR:000001131 biolink:Protein cysteinyl leukotriene receptor A leukotriene receptor that in active form binds cysteinyl leukotriene. go-plus.json http://purl.obolibrary.org/obo/PR_000001131 PR:000001130 biolink:Protein cholecystokinin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human CCKAR or CCKBR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds cholecystokinin (CCK). go-plus.json fam:CCK_R http://purl.obolibrary.org/obo/PR_000001130 PR:000001133 biolink:Protein endothelin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human EDNRA or EDNRB genes, 1:1 orthologs thereof, or pro-orthologs thereof. The active form binds endothelins. go-plus.json http://purl.obolibrary.org/obo/PR_000001133 PR:000001135 biolink:Protein interleukin-1 alpha An interleukin-1 that is a translation product of the human IL1A gene or a 1:1 ortholog thereof. Critical mediator of the immune and inflammatory responses. go-plus.json IL-1 alpha|hematopoietin-1|IL1F1|IL1A http://purl.obolibrary.org/obo/PR_000001135 CHEBI:776 biolink:ChemicalSubstance 16alpha-hydroxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_776 chebi_ph7_3 PR:000001134 biolink:Protein growth hormone secretagogue/motilin receptor A rhodopsin-like G-protein coupled receptor whose active form binds either growth hormone secretagogues (principally ghrelin) or motilin. The motilin and ghrelin receptors are about 45% identical in amino acid sequence. go-plus.json http://purl.obolibrary.org/obo/PR_000001134 CHEBI:77360 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77360 PR:000001136 biolink:Protein interleukin-1 beta An interleukin-1 that is a translation product of the human IL1B gene or a 1:1 ortholog thereof. go-plus.json IL-1 beta|catabolin|IL1F2|IL1B http://purl.obolibrary.org/obo/PR_000001136 CHEBI:77366 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77366 CHEBI:53335 biolink:ChemicalSubstance (S)-3-hydroxy-3-methyl-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_53335 CHEBI:77369 biolink:ChemicalSubstance 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77369 chebi_ph7_3 CHEBI:77368 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77368 CHEBI:28368 biolink:ChemicalSubstance novobiocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_28368 PR:000001193 biolink:Protein beta-2 adrenergic receptor A beta adrenergic receptor that is a translation product of the human ADRB2 gene or a 1:1 ortholog thereof. go-plus.json beta(2)-adrenergic receptor|ADRB2|beta-2 adrenoreceptor|B2AR|ADRB2R|beta-2 adrenoceptor http://purl.obolibrary.org/obo/PR_000001193 PR:000001192 biolink:Protein beta-1 adrenergic receptor A beta adrenergic receptor that is a translation product of the human ADRB1 gene or a 1:1 ortholog thereof. go-plus.json beta-1 adrenoreceptor|ADRB1|B1AR|ADRB1R|beta-1 adrenoceptor http://purl.obolibrary.org/obo/PR_000001192 CHEBI:28364 biolink:ChemicalSubstance all-cis-5,8,11,14,17-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28364 PR:000001194 biolink:Protein beta-3 adrenergic receptor A beta adrenergic receptor that is a translation product of the human ADRB3 gene or a 1:1 ortholog thereof. go-plus.json ADRB3|beta-3 adrenoreceptor|B3bar|B3AR|ADRB3R|beta-3 adrenoceptor http://purl.obolibrary.org/obo/PR_000001194 PR:000001186 biolink:Protein alpha-2A adrenergic receptor An alpha-2 adrenergic receptor that is a translation product of the human ADRA2A gene or a 1:1 ortholog thereof. go-plus.json alpha-2A adrenoreceptor|alpha-2AAR|ADRA2R|alpha-2A adrenoceptor|ADRA2A|alpha-2 adrenergic receptor subtype C10|ADRAR http://purl.obolibrary.org/obo/PR_000001186 PR:000001185 biolink:Protein alpha-1D adrenergic receptor An alpha-1 adrenergic receptor that is a translation product of the human ADRA1D gene or a 1:1 ortholog thereof. go-plus.json alpha-1D adrenoreceptor|ADRA1D|alpha-adrenergic receptor 1a|alpha-1D adrenoceptor|ADRA1A|Gpcr8|alpha-1A adrenergic receptor http://purl.obolibrary.org/obo/PR_000001185 PR:000001188 biolink:Protein alpha-2C adrenergic receptor An alpha-2 adrenergic receptor that is a translation product of the human ADRA2C gene or a 1:1 ortholog thereof. go-plus.json alpha-2 adrenergic receptor subtype C4|alpha-2C adrenoreceptor|ADRA2RL2|alpha-2CAR|ADRA2C|ADRA2L2|alpha-2C adrenoceptor http://purl.obolibrary.org/obo/PR_000001188 PR:000001187 biolink:Protein alpha-2B adrenergic receptor An alpha-2 adrenergic receptor that is a translation product of the human ADRA2B gene or a 1:1 ortholog thereof. go-plus.json alpha-2B adrenoreceptor|ADRA2RL1|alpha-2 adrenergic receptor subtype C2|alpha-2BAR|ADRA2B|alpha-2B adrenoceptor|ADRA2L1 http://purl.obolibrary.org/obo/PR_000001187 CHEBI:77372 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77372 CHEBI:77371 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77371 CHEBI:77370 biolink:ChemicalSubstance 1-palmitoyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77370 chebi_ph7_3 CHEBI:77377 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77377 CHEBI:77379 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_77379 CHEBI:28377 biolink:ChemicalSubstance plastoquinone-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_28377 chebi_ph7_3 CHEBI:28376 biolink:ChemicalSubstance 6-acetamido-2-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28376 CHEBI:28379 biolink:ChemicalSubstance (R)-3-methyl-2-oxovaleric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28379 CHEBI:43991 biolink:ChemicalSubstance malonamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_43991 CHEBI:28375 biolink:ChemicalSubstance dTDP-3-amino-3,4,6-trideoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28375 PR:000001197 biolink:Protein chemokine receptor CCR1/3/1L A chemokine receptor that is a translation product of the human CCR1 or CCR3 genes, the mouse CCR1L1 gene, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000001197 UBERON:0011932 biolink:AnatomicalEntity pilosebaceous unit An epidermal invagination that has as parts a hair follicle, a sebaceous gland, and arrector pili muscle go-plus.json pilosebaceous apparatus|pilo-sebaceous unit|fabrica pilosebacea|pilosebaceous gland|pilo-sebaceous apparatus http://purl.obolibrary.org/obo/UBERON_0011932 PR:000001199 biolink:Protein C-C chemokine receptor type 2 A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13. go-plus.json C-C CKR-2|MCP-1-R|CC-CKR-2|CCR2|MCP-1 receptor|CMKBR2|chemokine receptor CCR2|CCR-2|monocyte chemoattractant protein 1 receptor|JE/FIC receptor|CD192 http://purl.obolibrary.org/obo/PR_000001199 UBERON:0011931 biolink:AnatomicalEntity nasal hair Hair in the nose go-plus.json hair of nose|hair of vestibular part of nose|nose hair http://purl.obolibrary.org/obo/UBERON_0011931 UBERON:0011930 biolink:AnatomicalEntity preganglionic parasympathetic fiber A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion go-plus.json parasympathetic preganglionic fiber http://purl.obolibrary.org/obo/UBERON_0011930 CHEBI:799 biolink:ChemicalSubstance 3,17-dioxoandrost-4-en-19-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_799 chebi_ph7_3 CHEBI:798 biolink:ChemicalSubstance 19-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_798 chebi_ph7_3 CHEBI:43997 biolink:ChemicalSubstance N(6),N(6)-dimethyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_43997 CHEBI:77388 biolink:ChemicalSubstance tricaprin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77388 chebi_ph7_3 CHEBI:77387 biolink:ChemicalSubstance 2,3-dihexanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77387 chebi_ph7_3 CHEBI:53310 biolink:ChemicalSubstance copolymer macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53310 CHEBI:77386 biolink:ChemicalSubstance tricaproin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77386 chebi_ph7_3 CHEBI:791 biolink:ChemicalSubstance 17beta-estradiol 17-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_791 CHEBI:77389 biolink:ChemicalSubstance trilaurin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77389 chebi_ph7_3 CHEBI:363227 biolink:ChemicalSubstance 6alpha,20xi-murideoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_363227 CHEBI:53309 biolink:ChemicalSubstance polyanionic macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53309 CHEBI:28349 biolink:ChemicalSubstance alpha-L-fucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_28349 chebi_ph7_3 CHEBI:28343 biolink:ChemicalSubstance 3-O-alpha-mycarosylerythronolide B go-plus.json http://purl.obolibrary.org/obo/CHEBI_28343 chebi_ph7_3 PR:000001171 biolink:Protein B1 bradykinin receptor A bradykinin receptor that is a translation product of the human BDKRB1 gene or a 1:1 ortholog thereof. The preferred ligand is bradykinin. go-plus.json B1R|BDKRB1|Bdkrb|BRADYB1|BK-1 receptor http://purl.obolibrary.org/obo/PR_000001171 CHEBI:28340 biolink:ChemicalSubstance L-2-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_28340 PR:000001172 biolink:Protein B2 bradykinin receptor A bradykinin receptor that is a translation product of the human BDKRB2 gene or a 1:1 ortholog thereof. The preferred ligand is bradykinin. go-plus.json BKR2|B2R|BDKRB2|BK-2 receptor http://purl.obolibrary.org/obo/PR_000001172 CHEBI:77391 biolink:ChemicalSubstance trimyristin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77391 chebi_ph7_3 UBERON:0011921 biolink:AnatomicalEntity connecting stalk blood islands go-plus.json blood island of umbilical vesicle|insula sanguinea vesiculae umbilicalis http://purl.obolibrary.org/obo/UBERON_0011921 CHEBI:77390 biolink:ChemicalSubstance 2,3-didodecanoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77390 chebi_ph7_3 UBERON:0011926 biolink:AnatomicalEntity postganglionic sympathetic fiber A noradrenergic or adrenergic axonal fiber projecting from a sympathetic ganglion to an effector organ go-plus.json sympathetic postganglionic fiber|postganglionic sympathetic fiber http://purl.obolibrary.org/obo/UBERON_0011926 CHEBI:77395 biolink:ChemicalSubstance 2,3-distearoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77395 chebi_ph7_3 CHEBI:77394 biolink:ChemicalSubstance 2,3-dipalmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77394 chebi_ph7_3 UBERON:0011925 biolink:AnatomicalEntity preganglionic autonomic fiber Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released. go-plus.json preganglionic autonomic fibre|preganglionic nerve fiber http://purl.obolibrary.org/obo/UBERON_0011925 CHEBI:77393 biolink:ChemicalSubstance tripalmitin go-plus.json http://purl.obolibrary.org/obo/CHEBI_77393 chebi_ph7_3 UBERON:0011924 biolink:AnatomicalEntity postganglionic autonomic fiber Nerve fibers which project from cell bodies of autonomic ganglia to synapses on target organs. go-plus.json postganglionic autonomic fibre|postganglionic nerve fiber http://purl.obolibrary.org/obo/UBERON_0011924 CHEBI:43986 biolink:ChemicalSubstance N(6),N(6)-dimethyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_43986 CHEBI:77392 biolink:ChemicalSubstance 2,3-dimyristoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77392 chebi_ph7_3 CHEBI:77399 biolink:ChemicalSubstance D-alpha-phenylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77399 chebi_ph7_3 UBERON:0011929 biolink:AnatomicalEntity postganglionic parasympathetic fiber A cholinergic axonal fiber projecting from a parasympathetic ganglion to an effector organ go-plus.json parasympathetic postganglionic fiber http://purl.obolibrary.org/obo/UBERON_0011929 CHEBI:77398 biolink:ChemicalSubstance 2-amino-2-phenylacetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_77398 chebi_ph7_3 UBERON:0011927 biolink:AnatomicalEntity preganglionic sympathetic fiber A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion go-plus.json sympathetic preganglionic fiber http://purl.obolibrary.org/obo/UBERON_0011927 CHEBI:77396 biolink:ChemicalSubstance long-chain primary fatty alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77396 chebi_ph7_3 CHEBI:28359 biolink:ChemicalSubstance (-)-beta-pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_28359 chebi_ph7_3 CHEBI:28358 biolink:ChemicalSubstance rac-lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_28358 CHEBI:28354 biolink:ChemicalSubstance 1-deoxy-D-xylulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_28354 chebi_ph7_3 PR:000001182 biolink:Protein adrenocorticotropic hormone receptor A melanocortin receptor that is a translation product of the human MC2R gene or a 1:1 ortholog thereof. The preferred ligand is ACTH. go-plus.json ACTHR|MC2R|melanocortin receptor 2|adrenocorticotropin receptor|ACTH receptor|MC2-R|ACTH-R http://purl.obolibrary.org/obo/PR_000001182 PR:000001184 biolink:Protein alpha-1B adrenergic receptor An alpha-1 adrenergic receptor that is a translation product of the human ADRA1B gene or a 1:1 ortholog thereof. go-plus.json alpha-1B adrenoreceptor|ADRA1B|alpha-1B adrenoceptor http://purl.obolibrary.org/obo/PR_000001184 CHEBI:28353 biolink:ChemicalSubstance 4-hydroxycinnamaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_28353 chebi_ph7_3 PR:000001183 biolink:Protein alpha-1A adrenergic receptor An alpha-1 adrenergic receptor that is a translation product of the human ADRA1A gene or a 1:1 ortholog thereof. go-plus.json alpha-1A adrenoreceptor|ADRA1A|alpha-1A adrenoceptor|alpha-1C adrenergic receptor|alpha-adrenergic receptor 1c|ADRA1C http://purl.obolibrary.org/obo/PR_000001183 UBERON:0011919 biolink:AnatomicalEntity yolk sac blood island masses of developing blood cells attached to endothelium in the yolk sac go-plus.json visceral yolk sac blood island|yolk sac blood islands http://purl.obolibrary.org/obo/UBERON_0011919 CHEBI:67939 biolink:ChemicalSubstance erythrodiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_67939 chebi_ph7_3 CHEBI:133172 biolink:ChemicalSubstance 2-hydroxydecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_133172 CHEBI:133174 biolink:ChemicalSubstance 2-hydroxydecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_133174 chebi_ph7_3 CHEBI:133134 biolink:ChemicalSubstance prostaglandin H3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133134 chebi_ph7_3 CHEBI:133133 biolink:ChemicalSubstance prostaglandin G3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133133 chebi_ph7_3 CHEBI:133135 biolink:ChemicalSubstance chromenochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_133135 PR:000001105 biolink:Protein C5a anaphylatoxin chemotactic receptor A complement peptide receptor whose active form binds C5a anaphylatoxin. go-plus.json http://purl.obolibrary.org/obo/PR_000001105 CHEBI:133132 biolink:ChemicalSubstance prostaglandin E3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_133132 chebi_ph7_3 CHEBI:133131 biolink:ChemicalSubstance spiro-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_133131 CHEBI:77307 biolink:ChemicalSubstance cardioprotective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_77307 CHEBI:77305 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_77305 chebi_ph7_3 CHEBI:67987 biolink:ChemicalSubstance ginsenoside Rg1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_67987 chebi_ph7_3 CHEBI:53391 biolink:ChemicalSubstance poly(3-hydroxyvalerate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_53391 chebi_ph7_3 CHEBI:53390 biolink:ChemicalSubstance poly(hydroxyvalerate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_53390 CHEBI:53392 biolink:ChemicalSubstance poly(5-hydroxyvalerate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_53392 chebi_ph7_3 PR:000001113 biolink:Protein interleukin-25 An interleukin-17 that is a translation product of the human IL25 gene or a 1:1 ortholog thereof. go-plus.json IL-17E|IL-25|IL25|interleukin-17E|IL17E http://purl.obolibrary.org/obo/PR_000001113 CHEBI:67989 biolink:ChemicalSubstance ginsenoside Rb1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_67989 chebi_ph7_3 CHEBI:67988 biolink:ChemicalSubstance ginsenoside Rd go-plus.json http://purl.obolibrary.org/obo/CHEBI_67988 chebi_ph7_3 PR:000001115 biolink:Protein alpha-1 adrenergic receptor An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that activate a phosphatidylinositol-calcium second messenger system. go-plus.json http://purl.obolibrary.org/obo/PR_000001115 PR:000001116 biolink:Protein alpha-2 adrenergic receptor An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that cause inhibition of adenylate cyclase. go-plus.json http://purl.obolibrary.org/obo/PR_000001116 PR:000001119 biolink:Protein animal opsin A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPN1LW, OPN1MW, OPN1SW, RHO, OPN3, OPN4, or OPN5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof in Metazoa. The active form binds a vitamin A-based retinaldehyde chromophore through a Schiff base linkage to a Lys residue in the seventh transmembrane alpha helix. go-plus.json opsin receptor|type II opsin http://purl.obolibrary.org/obo/PR_000001119 CHEBI:77304 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_77304 chebi_ph7_3 CHEBI:77303 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77303 chebi_ph7_3 CHEBI:77302 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77302 chebi_ph7_3 CHEBI:77301 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_77301 chebi_ph7_3 CHEBI:77318 biolink:ChemicalSubstance pregnane X receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_77318 CHEBI:67991 biolink:ChemicalSubstance (20S)-ginsenoside Rg3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_67991 chebi_ph7_3 CHEBI:53388 biolink:ChemicalSubstance poly(hydroxybutyrate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_53388 CHEBI:77310 biolink:ChemicalSubstance (E)-2-methylpentadec-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_77310 chebi_ph7_3 CHEBI:53387 biolink:ChemicalSubstance poly(hydroxyalkanoate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_53387 CHEBI:732 biolink:ChemicalSubstance 5beta-dihydrocortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_732 chebi_ph7_3 CHEBI:53376 biolink:ChemicalSubstance gamma-poly(glutamate) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53376 CHEBI:77326 biolink:ChemicalSubstance androstane receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_77326 CHEBI:53373 biolink:ChemicalSubstance gamma-poly(glutamic acid) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_53373 GO:0033769 biolink:MolecularActivity glyceollin synthase activity Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O. MetaCyc:2.5.1.36-RXN|EC:1.14.13.85 go-plus.json 2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity|dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity http://purl.obolibrary.org/obo/GO_0033769 GO:0033768 biolink:CellularComponent SUMO-targeted ubiquitin ligase complex A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0033768 GO:0033767 biolink:MolecularActivity 4-hydroxyacetophenone monooxygenase activity Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+). EC:1.14.13.84|RHEA:22916|UM-BBD_reactionID:r0756|MetaCyc:1.14.13.84-RXN|KEGG_REACTION:R06892 go-plus.json (4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity|HAPMO http://purl.obolibrary.org/obo/GO_0033767 GO:0033766 biolink:MolecularActivity 2-hydroxyquinoline 8-monooxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol. RHEA:22080|EC:1.14.13.61|KEGG_REACTION:R05158|MetaCyc:1.14.13.61-RXN go-plus.json 2-oxo-1,2-dihydroquinoline 8-monooxygenase activity|quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity http://purl.obolibrary.org/obo/GO_0033766 GO:0018128 biolink:MolecularActivity obsolete peptidyl-serine cyclase activity OBSOLETE. (Was not defined before being made obsolete). EC:4.2.1.- go-plus.json peptidyl-serine cyclase activity http://purl.obolibrary.org/obo/GO_0018128 GO:0018127 biolink:MolecularActivity NAD(P)-serine ADP-ribosyltransferase activity Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0018127 GO:0018129 biolink:MolecularActivity peptidyl-oxazoline dehydrogenase activity Catalysis of the reduction of a peptide-linked oxazoline to oxazole. go-plus.json http://purl.obolibrary.org/obo/GO_0018129 CHEBI:138463 biolink:ChemicalSubstance N-(12-oxojasmonyl)-L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138463 chebi_ph7_3 GO:0018124 biolink:BiologicalProcess peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue. RESID:AA0233 go-plus.json http://purl.obolibrary.org/obo/GO_0018124 GO:0033765 biolink:MolecularActivity steroid dehydrogenase activity, acting on the CH-CH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0033765 GO:0018123 biolink:BiologicalProcess peptidyl-cysteine ADP-ribosylation The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine. RESID:AA0169 go-plus.json http://purl.obolibrary.org/obo/GO_0018123 CHEBI:138462 biolink:ChemicalSubstance (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_138462 chebi_ph7_3 GO:0033764 biolink:MolecularActivity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0033764 GO:0033763 biolink:MolecularActivity proline 3-hydroxylase activity Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2. EC:1.14.11.28|MetaCyc:1.14.11.28-RXN|RHEA:20265 go-plus.json P-3-H|L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0033763 CHEBI:138461 biolink:ChemicalSubstance (3R)-3-hydroxy-2,3-dihydrotabersoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_138461 chebi_ph7_3 GO:0018126 biolink:BiologicalProcess protein hydroxylation The addition of a hydroxy group to a protein amino acid. go-plus.json protein amino acid hydroxylation http://purl.obolibrary.org/obo/GO_0018126 GO:0018125 biolink:BiologicalProcess peptidyl-cysteine methylation The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine. RESID:AA0234 go-plus.json http://purl.obolibrary.org/obo/GO_0018125 GO:0033762 biolink:BiologicalProcess response to glucagon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. go-plus.json response to glucagon stimulus http://purl.obolibrary.org/obo/GO_0033762 GO:0033761 biolink:MolecularActivity mugineic-acid 3-dioxygenase activity Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2. EC:1.14.11.25|RHEA:14509|MetaCyc:RXN-7982|KEGG_REACTION:R07186 go-plus.json mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|IDS2 http://purl.obolibrary.org/obo/GO_0033761 GO:0018120 biolink:BiologicalProcess peptidyl-arginine ADP-ribosylation The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine. RESID:AA0168 go-plus.json http://purl.obolibrary.org/obo/GO_0018120 GO:0033760 biolink:MolecularActivity 2'-deoxymugineic-acid 2'-dioxygenase activity Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate. KEGG_REACTION:R07185|EC:1.14.11.24|MetaCyc:1.14.11.24-RXN|RHEA:12200 go-plus.json 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity|IDS3 http://purl.obolibrary.org/obo/GO_0033760 GO:0018122 biolink:BiologicalProcess peptidyl-asparagine ADP-ribosylation The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine. RESID:AA0231 go-plus.json http://purl.obolibrary.org/obo/GO_0018122 GO:0018121 biolink:MolecularActivity NAD(P)-asparagine ADP-ribosyltransferase activity Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine. go-plus.json http://purl.obolibrary.org/obo/GO_0018121 CHEBI:138464 biolink:ChemicalSubstance N-(12-hydroxy-12-oxojasmonyl)-L-alpha-amino acid dianion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138464 chebi_ph7_3 GO:0018140 biolink:BiologicalProcess peptide cross-linking via L-cysteine thiazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0244 go-plus.json http://purl.obolibrary.org/obo/GO_0018140 GO:0033759 biolink:MolecularActivity flavone synthase activity Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O. EC:1.14.20.5|RHEA:10448|MetaCyc:RXN-8000 go-plus.json flavone synthase I activity|FNS I|flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity http://purl.obolibrary.org/obo/GO_0033759 CHEBI:138481 biolink:ChemicalSubstance N(5),N(5),N(5)-trimethyl-N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138481 chebi_ph7_3 GO:0033758 biolink:MolecularActivity clavaminate synthase activity Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O. MetaCyc:1.14.11.21-RXN|RHEA:20021|EC:1.14.11.21 go-plus.json clavaminate synthase 2 activity|clavaminic acid synthase activity|deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0033758 CHEBI:138480 biolink:ChemicalSubstance N(5),N(5)-dimethyl-N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138480 chebi_ph7_3 GO:0033757 biolink:MolecularActivity glucoside 3-dehydrogenase activity Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor. RHEA:16589|Wikipedia:Glucoside_3-dehydrogenase|MetaCyc:GLUCOSIDE-3-DEHYDROGENASE-RXN|EC:1.1.99.13 go-plus.json hexopyranoside-cytochrome c oxidoreductase|D-aldohexopyranoside dehydrogenase|D-aldohexoside:cytochrome c oxidoreductase|D-aldohexoside:acceptor 3-oxidoreductase|D-aldohexoside:(acceptor) 3-oxidoreductase http://purl.obolibrary.org/obo/GO_0033757 GO:0033756 biolink:MolecularActivity Oplophorus-luciferin 2-monooxygenase activity Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu. RHEA:20417|MetaCyc:RXN-3361|EC:1.13.12.13 go-plus.json Oplophorus luciferase activity|Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity http://purl.obolibrary.org/obo/GO_0033756 GO:0033755 biolink:MolecularActivity sulfur oxygenase/reductase activity Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+. RHEA:13957|MetaCyc:1.13.11.55-RXN|EC:1.13.11.55 go-plus.json sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity|sulfur oxygenase activity|sulphur oxygenase/reductase activity|SOR http://purl.obolibrary.org/obo/GO_0033755 GO:0043102 biolink:BiologicalProcess amino acid salvage Any process which produces an amino acid from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043102 GO:0043101 biolink:BiologicalProcess purine-containing compound salvage Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis. go-plus.json purine salvage http://purl.obolibrary.org/obo/GO_0043101 goslim_pir GO:0043104 biolink:BiologicalProcess positive regulation of GTP cyclohydrolase I activity Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I. go-plus.json upregulation of GTP cyclohydrolase I activity|up regulation of GTP cyclohydrolase I activity|activation of GTP cyclohydrolase I activity|stimulation of GTP cyclohydrolase I activity|up-regulation of GTP cyclohydrolase I activity http://purl.obolibrary.org/obo/GO_0043104 GO:0043103 biolink:BiologicalProcess hypoxanthine salvage Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis. go-plus.json adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage http://purl.obolibrary.org/obo/GO_0043103 GO:0043100 biolink:BiologicalProcess pyrimidine nucleobase salvage Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis. go-plus.json pyrimidine base salvage http://purl.obolibrary.org/obo/GO_0043100 GO:0043109 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043109 GO:0018139 biolink:BiologicalProcess peptide cross-linking via L-phenylalanine thiazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0243 go-plus.json http://purl.obolibrary.org/obo/GO_0018139 GO:0043106 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043106 GO:0043105 biolink:BiologicalProcess negative regulation of GTP cyclohydrolase I activity Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I. go-plus.json down regulation of GTP cyclohydrolase I activity|downregulation of GTP cyclohydrolase I activity|down-regulation of GTP cyclohydrolase I activity|inhibition of GTP cyclohydrolase I activity http://purl.obolibrary.org/obo/GO_0043105 GO:0018138 biolink:BiologicalProcess peptide cross-linking via L-serine thiazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0242 go-plus.json http://purl.obolibrary.org/obo/GO_0018138 GO:0043108 biolink:BiologicalProcess pilus retraction The process of withdrawing a pilus back into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043108 GO:0043107 biolink:BiologicalProcess type IV pilus-dependent motility Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility. go-plus.json social gliding motility|twitching motility|type four pilus-dependent motility|TFP-dependent motility|type 4 pilus-dependent motility|TFP-dependent movement http://purl.obolibrary.org/obo/GO_0043107 GO:0033754 biolink:MolecularActivity indoleamine 2,3-dioxygenase activity Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine. MetaCyc:RXN-8665|MetaCyc:RXN-8664|RHEA:14189|EC:1.13.11.52 go-plus.json IDO|D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity|tryptophan pyrrolase activity http://purl.obolibrary.org/obo/GO_0033754 GO:0018135 biolink:MolecularActivity obsolete peptidyl-cysteine cyclase activity OBSOLETE. (Was not defined before being made obsolete). EC:4.2.1.- go-plus.json peptidyl-cysteine cyclase activity http://purl.obolibrary.org/obo/GO_0018135 CHEBI:138473 biolink:ChemicalSubstance N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138473 chebi_ph7_3 GO:0018134 biolink:BiologicalProcess peptide cross-linking via glycine oxazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0240 go-plus.json http://purl.obolibrary.org/obo/GO_0018134 GO:0033753 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033753 GO:0033752 biolink:MolecularActivity acetylacetone-cleaving enzyme activity Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal. RHEA:12877|EC:1.13.11.50 go-plus.json acetylacetone-cleaving enzyme|Dke1|acetylacetone dioxygenase activity|acetylacetone:oxygen oxidoreductase activity|diketone cleaving dioxygenase activity|diketone cleaving enzyme http://purl.obolibrary.org/obo/GO_0033752 GO:0018137 biolink:BiologicalProcess peptide cross-linking via glycine thiazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0241 go-plus.json http://purl.obolibrary.org/obo/GO_0018137 GO:0033751 biolink:MolecularActivity linoleate 8R-lipoxygenase Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate. RHEA:22392 go-plus.json linoleate diol synthase activity|7,8-linoleate diol synthase (bifunctional enzyme)|5,8-linoleate diol synthase (bifunctional enzyme) http://purl.obolibrary.org/obo/GO_0033751 GO:0018136 biolink:MolecularActivity peptidyl-thiazoline dehydrogenase activity Catalysis of the reduction of a peptide-linked thiazoline to thiazole. go-plus.json http://purl.obolibrary.org/obo/GO_0018136 GO:0018131 biolink:BiologicalProcess oxazole or thiazole biosynthetic process The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position. go-plus.json oxazole or thiazole anabolism|oxazole or thiazole synthesis|oxazole or thiazole biosynthesis|oxazole or thiazole formation http://purl.obolibrary.org/obo/GO_0018131 GO:0033750 biolink:BiologicalProcess ribosome localization A process in which a ribosome is transported to, and/or maintained in, a specific location. go-plus.json ribosome localisation|establishment of ribosome localisation|establishment of ribosome localization http://purl.obolibrary.org/obo/GO_0033750 CHEBI:138478 biolink:ChemicalSubstance N(5)-methyl-N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138478 chebi_ph7_3 GO:0018130 biolink:BiologicalProcess heterocycle biosynthetic process The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). go-plus.json heterocycle anabolism|heterocycle biosynthesis|heterocycle synthesis|heterocycle formation http://purl.obolibrary.org/obo/GO_0018130 GO:0018133 biolink:BiologicalProcess peptide cross-linking via L-cysteine oxazolinecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue. RESID:AA0239 go-plus.json http://purl.obolibrary.org/obo/GO_0018133 GO:0018132 biolink:BiologicalProcess peptide cross-linking via L-cysteine oxazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0238 go-plus.json http://purl.obolibrary.org/obo/GO_0018132 GO:0033749 biolink:MolecularActivity histone H3-methyl-arginine-3 demethylase activity Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. go-plus.json histone H3R3me demethylase activity|histone demethylase activity (H4-R3 specific) http://purl.obolibrary.org/obo/GO_0033749 GO:0033748 biolink:MolecularActivity hydrogenase (acceptor) activity Catalysis of the reaction: H2 + A = AH2. EC:1.12.99.6|MetaCyc:RXN0-5256|RHEA:12116|MetaCyc:RXN0-4141 go-plus.json uptake hydrogenase activity|hydrogen-lyase activity|H2 producing hydrogenase activity|hydrogen:(acceptor) oxidoreductase activity|hydrogenlyase activity|hydrogen:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033748 GO:0033747 biolink:MolecularActivity obsolete versatile peroxidase activity OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O. go-plus.json polyvalent peroxidase activity|versatile peroxidase activity|reactive-black-5:hydrogen-peroxide oxidoreductase activity|VP|hybrid peroxidase activity http://purl.obolibrary.org/obo/GO_0033747 GO:0033746 biolink:MolecularActivity histone H3-methyl-arginine-2 demethylase activity Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. go-plus.json histone H3R2me demethylase activity|histone demethylase activity (H3-R2 specific) http://purl.obolibrary.org/obo/GO_0033746 GO:0033745 biolink:MolecularActivity L-methionine-(R)-S-oxide reductase activity Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin. RHEA:21260|MetaCyc:1.8.4.14-RXN|EC:1.8.4.14 go-plus.json FRMsr|L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity|free-methionine (R)-S-oxide reductase activity|free met-R-(o) reductase activity http://purl.obolibrary.org/obo/GO_0033745 GO:0008789 biolink:MolecularActivity altronate dehydratase activity Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O. RHEA:15957|KEGG_REACTION:R01540|EC:4.2.1.7|MetaCyc:ALTRODEHYDRAT-RXN go-plus.json D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-altronate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0008789 GO:0008788 biolink:MolecularActivity alpha,alpha-phosphotrehalase activity Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate. MetaCyc:TRE6PHYDRO-RXN|RHEA:23008|EC:3.2.1.93 go-plus.json trehalose-6-phosphate hydrolase activity|alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity|phosphotrehalase activity http://purl.obolibrary.org/obo/GO_0008788 GO:0033744 biolink:MolecularActivity L-methionine:thioredoxin-disulfide S-oxidoreductase activity Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. RHEA:19993|MetaCyc:1.8.4.13-RXN|KEGG_REACTION:R07606|EC:1.8.4.13 go-plus.json acetylmethionine sulfoxide reductase activity|L-methionine:oxidized-thioredoxin S-oxidoreductase activity|L-methionine-(S)-S-oxide reductase activity|methionine sulfoxide reductase activity|fSMsr|methionine-S-oxide reductase activity|free-methionine (S)-S-oxide reductase activity|methyl sulfoxide reductase I and II activity http://purl.obolibrary.org/obo/GO_0033744 GO:0043113 biolink:BiologicalProcess receptor clustering The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. go-plus.json http://purl.obolibrary.org/obo/GO_0043113 GO:0008787 biolink:MolecularActivity allose kinase activity Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate. MetaCyc:ALLOSE-KINASE-RXN|RHEA:14805|EC:2.7.1.55 go-plus.json D-allokinase activity|D-allose-6-kinase activity|ATP:D-allose 6-phosphotransferase activity|allokinase activity|allokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0008787 GO:0043112 biolink:BiologicalProcess receptor metabolic process The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json receptor metabolism http://purl.obolibrary.org/obo/GO_0043112 GO:0008786 biolink:MolecularActivity allose 6-phosphate isomerase activity Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate. RHEA:28430|MetaCyc:RXN0-303 go-plus.json http://purl.obolibrary.org/obo/GO_0008786 GO:0043115 biolink:MolecularActivity precorrin-2 dehydrogenase activity Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin. MetaCyc:DIMETHUROPORDEHYDROG-RXN|KEGG_REACTION:R03947|EC:1.3.1.76|RHEA:15613 go-plus.json dihydrosirohydrochlorin dehydrogenase activity|siroheme synthase activity|precorrin-2:NAD+ oxidoreductase activity|Met8p|CysG|SirC|precorrin-2 oxidase activity|1,3-dimethyluroporphyrinogen III dehydrogenase activity http://purl.obolibrary.org/obo/GO_0043115 GO:0008785 biolink:MolecularActivity alkyl hydroperoxide reductase activity Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol. Reactome:R-HSA-1222526|UM-BBD_reactionID:r0684 go-plus.json http://purl.obolibrary.org/obo/GO_0008785 GO:0043114 biolink:BiologicalProcess regulation of vascular permeability Any process that modulates the extent to which blood vessels can be pervaded by fluid. go-plus.json http://purl.obolibrary.org/obo/GO_0043114 GO:0008784 biolink:MolecularActivity alanine racemase activity Catalysis of the reaction: L-alanine = D-alanine. RHEA:20249|KEGG_REACTION:R00401|EC:5.1.1.1|MetaCyc:ALARACECAT-RXN go-plus.json L-alanine racemase activity http://purl.obolibrary.org/obo/GO_0008784 GO:0008783 biolink:MolecularActivity agmatinase activity Catalysis of the reaction: agmatine + H(2)O = putrescine + urea. RHEA:13929|KEGG_REACTION:R01157|EC:3.5.3.11|Reactome:R-HSA-350604|MetaCyc:AGMATIN-RXN go-plus.json SpeB|agmatine ureohydrolase activity|agmatine amidinohydrolase http://purl.obolibrary.org/obo/GO_0008783 GO:0008782 biolink:MolecularActivity adenosylhomocysteine nucleosidase activity Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine. MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN|RHEA:17805|EC:3.2.2.9 go-plus.json AdoHcy/MTA nucleosidase activity|S-adenosylhomocysteine nucleosidase activity|5'-methyladenosine nucleosidase activity|S-adenosyl-L-homocysteine homocysteinylribohydrolase activity|S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity|S-adenosylhomocysteine hydrolase activity http://purl.obolibrary.org/obo/GO_0008782 GO:0008781 biolink:MolecularActivity N-acylneuraminate cytidylyltransferase activity Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate. Reactome:R-HSA-4084982|MetaCyc:ACYLNEURAMINATE-CYTIDYLYLTRANSFERASE-RXN|RHEA:11344|EC:2.7.7.43 go-plus.json cytidine 5'-monophosphosialic acid synthetase activity|CMP-sialate synthetase activity|acetylneuraminate cytidylyltransferase activity|cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity|CMP-N-acetylneuraminic acid synthase activity|cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity|acylneuraminate cytidyltransferase activity|cytidine monophosphosialic acid synthetase activity|CMP-N-acetylneuraminate synthetase activity|cytidine monophosphoacetylneuraminic synthetase activity|CMP-sialic synthetase activity|CMP-Neu5Ac synthetase activity|CMP-sialate pyrophosphorylase activity|CMP-sialate synthase activity|CMP-sialic acid synthetase activity|CMP-sialate diphosphorylase activity|CMP-NeuNAc synthetase activity|CMP-NeuAc synthetase activity|CTP:N-acylneuraminate cytidylyltransferase activity|CMP-N-acetylneuraminate synthase activity|CMP-N-acetylneuraminic acid synthetase activity|cytidine monophosphosialate pyrophosphorylase activity|cytidine monophosphosialate synthetase activity|CMP-NANA synthetase activity http://purl.obolibrary.org/obo/GO_0008781 GO:0043111 biolink:BiologicalProcess replication fork arrest Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected. go-plus.json replication fork blocking|replication fork stalling|negative regulation of DNA replication at replication fork barrier http://purl.obolibrary.org/obo/GO_0043111 GO:0008780 biolink:MolecularActivity acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. RHEA:13925|MetaCyc:UDPNACETYLGLUCOSAMACYLTRANS-RXN|EC:2.3.1.129 go-plus.json UDP-N-acetylglucosamine acyltransferase activity|uridine diphosphoacetylglucosamine acyltransferase activity|acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity|acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase|acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity|(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity http://purl.obolibrary.org/obo/GO_0008780 GO:0043110 biolink:MolecularActivity rDNA spacer replication fork barrier binding Binding to replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription. go-plus.json RFB binding http://purl.obolibrary.org/obo/GO_0043110 GO:0008790 biolink:MolecularActivity arabinose isomerase activity Catalysis of the reaction: D-arabinose = D-ribulose. MetaCyc:DARABISOM-RXN|EC:5.3.1.3|RHEA:13849 go-plus.json D-arabinose(L-fucose) isomerase activity|D-arabinose isomerase activity|D-arabinose aldose-ketose-isomerase activity|D-arabinose ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0008790 GO:0018109 biolink:BiologicalProcess peptidyl-arginine phosphorylation The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine. RESID:AA0222 go-plus.json http://purl.obolibrary.org/obo/GO_0018109 GO:0018106 biolink:BiologicalProcess peptidyl-histidine phosphorylation The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine). RESID:AA0036|RESID:AA0035 go-plus.json http://purl.obolibrary.org/obo/GO_0018106 GO:0043117 biolink:BiologicalProcess positive regulation of vascular permeability Any process that increases the extent to which blood vessels can be pervaded by fluid. go-plus.json up regulation of vascular permeability|activation of vascular permeability|stimulation of vascular permeability|up-regulation of vascular permeability|upregulation of vascular permeability http://purl.obolibrary.org/obo/GO_0043117 NCBITaxon:7070 biolink:OrganismalEntity Tribolium castaneum go-plus.json rust-red flour beetle|red flour beetle http://purl.obolibrary.org/obo/NCBITaxon_7070 GO:0018105 biolink:BiologicalProcess peptidyl-serine phosphorylation The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. RESID:AA0037 go-plus.json http://purl.obolibrary.org/obo/GO_0018105 GO:0043116 biolink:BiologicalProcess negative regulation of vascular permeability Any process that reduces the extent to which blood vessels can be pervaded by fluid. go-plus.json down regulation of vascular permeability|downregulation of vascular permeability|down-regulation of vascular permeability|inhibition of vascular permeability http://purl.obolibrary.org/obo/GO_0043116 GO:0018108 biolink:BiologicalProcess peptidyl-tyrosine phosphorylation The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. RESID:AA0039 go-plus.json http://purl.obolibrary.org/obo/GO_0018108 GO:0043119 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043119 GO:0018107 biolink:BiologicalProcess peptidyl-threonine phosphorylation The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. RESID:AA0038 go-plus.json http://purl.obolibrary.org/obo/GO_0018107 GO:0043118 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043118 GO:0033743 biolink:MolecularActivity peptide-methionine (R)-S-oxide reductase activity Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. RHEA:24164|MetaCyc:1.8.4.12-RXN|Reactome:R-HSA-5676917|KEGG_REACTION:R07607|EC:1.8.4.12 go-plus.json methionine S-oxide reductase (R-form oxidizing) activity|methionine sulfoxide reductase activity|peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity|methionine S-oxide reductase activity|SelX|pMSR|SelR|MsrB|pMRsr|methionine sulfoxide reductase B activity|PilB|selenoprotein R|protein-methionine-R-oxide reductase activity http://purl.obolibrary.org/obo/GO_0033743 CHEBI:138441 biolink:ChemicalSubstance (3R,4R)-3-acyl-4-(hydroxymethyl)oxolan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138441 chebi_ph7_3 GO:0018102 biolink:BiologicalProcess peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine. RESID:AA0215 go-plus.json http://purl.obolibrary.org/obo/GO_0018102 GO:0018101 biolink:BiologicalProcess protein citrullination The hydrolysis of peptidyl-arginine to form peptidyl-citrulline. RESID:AA0214 go-plus.json peptidyl-citrulline biosynthetic process from peptidyl-arginine|peptidyl-citrulline synthesis from peptidyl-arginine|peptidyl-citrulline anabolism from peptidyl-arginine|deimination|peptidyl-citrulline formation from peptidyl-arginine http://purl.obolibrary.org/obo/GO_0018101 GO:0033742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033742 CHEBI:138440 biolink:ChemicalSubstance (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138440 chebi_ph7_3 GO:0018104 biolink:BiologicalProcess peptidoglycan-protein cross-linking The process of covalently linking peptidoglycan (murein) to proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0018104 GO:0033741 biolink:MolecularActivity adenylyl-sulfate reductase (glutathione) activity Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione. RHEA:14141|MetaCyc:1.8.4.9-RXN|KEGG_REACTION:R05717|EC:1.8.4.9 go-plus.json 5'-adenylylsulfate reductase activity|AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity|plant-type 5'-adenylylsulfate reductase activity|AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity http://purl.obolibrary.org/obo/GO_0033741 GO:0033740 biolink:MolecularActivity hydroxylamine oxidoreductase activity Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor. EC:1.7.2.8|MetaCyc:1.7.99.8-RXN|RHEA:23232 go-plus.json hydroxylamine:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033740 GO:0018103 biolink:BiologicalProcess protein C-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom. RESID:AA0217 go-plus.json protein amino acid C-linked glycosylation http://purl.obolibrary.org/obo/GO_0018103 CHEBI:138445 biolink:ChemicalSubstance O(3)-(poly[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)]-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine polyanionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138445 chebi_ph7_3 CHEBI:138444 biolink:ChemicalSubstance O(3)-(beta-D-GlcA-(1->3)-poly[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)]-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine polyanionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138444 chebi_ph7_3 CHEBI:138443 biolink:ChemicalSubstance O(3)-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138443 chebi_ph7_3 CHEBI:138442 biolink:ChemicalSubstance O(3)-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138442 chebi_ph7_3 GO:0033739 biolink:MolecularActivity preQ1 synthase activity Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH. RHEA:13409|MetaCyc:RXN0-4022|EC:1.7.1.13|KEGG_REACTION:R07605 go-plus.json preQ0 oxidoreductase activity|queuine:NADP+ oxidoreductase activity|preQ0 reductase activity|YkvM|7-cyano-7-deazaguanine reductase activity|QueF|7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity|queuine synthase activity http://purl.obolibrary.org/obo/GO_0033739 GO:0033738 biolink:MolecularActivity methylenetetrahydrofolate reductase (ferredoxin) activity Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin. RHEA:14229|MetaCyc:RXN-5061|EC:1.5.7.1 go-plus.json 5-methyltetrahydrofolate:ferredoxin oxidoreductase activity|5,10-methylenetetrahydrofolate reductase activity http://purl.obolibrary.org/obo/GO_0033738 GO:0033737 biolink:MolecularActivity 1-pyrroline dehydrogenase activity Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+. EC:1.2.1.19|MetaCyc:1.5.1.35-RXN go-plus.json YdcW|gamma-aminobutyraldehyde dehydrogenase activity|1-pyrroline:NAD+ oxidoreductase activity|ABALDH http://purl.obolibrary.org/obo/GO_0033737 GO:0033736 biolink:MolecularActivity L-lysine 6-oxidase activity Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+). RHEA:22548|EC:1.4.3.20|KEGG_REACTION:R07598|MetaCyc:1.4.3.20-RXN go-plus.json L-lysine-epsilon-oxidase activity|L-lysine:oxygen 6-oxidoreductase (deaminating) activity|marinocine|Lod|LodA http://purl.obolibrary.org/obo/GO_0033736 GO:0033735 biolink:MolecularActivity aspartate dehydrogenase activity Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+. EC:1.4.1.21|KEGG_REACTION:R07165|KEGG_REACTION:R07164|MetaCyc:1.4.1.21-RXN go-plus.json L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity|NADP+-dependent aspartate dehydrogenase activity|NAD-dependent aspartate dehydrogenase activity|NADH2-dependent aspartate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0033735 GO:0033734 biolink:MolecularActivity (R)-benzylsuccinyl-CoA dehydrogenase activity Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein. RHEA:20876|UM-BBD_reactionID:r0330|EC:1.3.8.3 go-plus.json BbsG|(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity|(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033734 CHEBI:2290 biolink:ChemicalSubstance 7alpha-hydroxy-5beta-cholestan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_2290 chebi_ph7_3 GO:0008799 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008799 GO:0033733 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033733 GO:0043124 biolink:BiologicalProcess negative regulation of I-kappaB kinase/NF-kappaB signaling Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling. go-plus.json negative regulation of I-kappaB kinase/NF-kappaB cascade|down regulation of I-kappaB kinase/NF-kappaB cascade|downregulation of I-kappaB kinase/NF-kappaB cascade|down-regulation of I-kappaB kinase/NF-kappaB cascade|inhibition of I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0043124 GO:0008798 biolink:MolecularActivity beta-aspartyl-peptidase activity Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide. Reactome:R-HSA-5692495|EC:3.4.19.5|Reactome:R-HSA-5696365|MetaCyc:3.4.19.5-RXN go-plus.json beta-aspartyl peptidase activity|beta-aspartyl dipeptidase activity http://purl.obolibrary.org/obo/GO_0008798 GO:0043123 biolink:BiologicalProcess positive regulation of I-kappaB kinase/NF-kappaB signaling Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling. go-plus.json up-regulation of I-kappaB kinase/NF-kappaB cascade|upregulation of I-kappaB kinase/NF-kappaB cascade|stimulation of I-kappaB kinase/NF-kappaB cascade|up regulation of I-kappaB kinase/NF-kappaB cascade|activation of I-kappaB kinase/NF-kappaB cascade|positive regulation of I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0043123 GO:0008797 biolink:MolecularActivity aspartate ammonia-lyase activity Catalysis of the reaction: L-aspartate = fumarate + NH3. RHEA:16601|EC:4.3.1.1|MetaCyc:ASPARTASE-RXN go-plus.json L-aspartase activity|aspartase activity|L-aspartate ammonia-lyase activity|L-aspartate ammonia-lyase (fumarate-forming)|fumaric aminase activity http://purl.obolibrary.org/obo/GO_0008797 GO:0043126 biolink:BiologicalProcess regulation of 1-phosphatidylinositol 4-kinase activity Any process that modulates the activity of the enzyme 1-phosphatidylinositol 4-kinase. go-plus.json regulation of PI4K activity http://purl.obolibrary.org/obo/GO_0043126 GO:0008796 biolink:MolecularActivity bis(5'-nucleosyl)-tetraphosphatase activity Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides. go-plus.json http://purl.obolibrary.org/obo/GO_0008796 GO:0008795 biolink:MolecularActivity NAD+ synthase activity Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. EC:6.3.1.5|MetaCyc:NAD-SYNTH-NH3-RXN|RHEA:21188 go-plus.json deamido-NAD+:ammonia ligase (AMP-forming)|NAD synthase activity|diphosphopyridine nucleotide synthetase activity|NAD+ synthetase activity|NAD synthase (AMP-forming)|nicotinamide adenine dinucleotide synthetase activity|NAD(+) synthetase activity|NAD synthetase activity http://purl.obolibrary.org/obo/GO_0008795 GO:0043125 biolink:MolecularActivity ErbB-3 class receptor binding Binding to the protein-tyrosine kinase receptor ErbB-3/HER3. go-plus.json HER3 receptor binding|Neu/ErbB-2 receptor activity http://purl.obolibrary.org/obo/GO_0043125 GO:0008794 biolink:MolecularActivity arsenate reductase (glutaredoxin) activity Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione. EC:1.20.4.1|MetaCyc:RXN-982|UM-BBD_reactionID:r0635|RHEA:22016 go-plus.json glutharedoxin:arsenate oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008794 GO:0043120 biolink:MolecularActivity tumor necrosis factor binding Binding to tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages. go-plus.json http://purl.obolibrary.org/obo/GO_0043120 GO:0008793 biolink:MolecularActivity aromatic-amino-acid:2-oxoglutarate aminotransferase activity Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate. RHEA:17533|MetaCyc:2.6.1.57-RXN|EC:2.6.1.57|UM-BBD_reactionID:r0297 go-plus.json aromatic amino acid aminotransferase activity|aromatic amino acid transferase activity|ArAT|aromatic aminotransferase activity|aromatic-amino-acid transaminase activity http://purl.obolibrary.org/obo/GO_0008793 GO:0043122 biolink:BiologicalProcess regulation of I-kappaB kinase/NF-kappaB signaling Any process that modulates I-kappaB kinase/NF-kappaB signaling. go-plus.json regulation of I-kappaB kinase/NF-kappaB cascade http://purl.obolibrary.org/obo/GO_0043122 GO:0008792 biolink:MolecularActivity arginine decarboxylase activity Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2). RHEA:17641|Reactome:R-HSA-350598|EC:4.1.1.19|MetaCyc:ARGDECARBOX-RXN|KEGG_REACTION:R00566 go-plus.json L-arginine carboxy-lyase activity|L-arginine carboxy-lyase (agmatine-forming)|SpeA http://purl.obolibrary.org/obo/GO_0008792 GO:0043121 biolink:MolecularActivity neurotrophin binding Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth. go-plus.json neurotrophin TRK receptor activity|neurotrophic factor binding|neurotrophin-4/5 binding|NT 4/5 binding|neurotrophin-3 binding|NT-4/5 binding|NT5 binding|NT-5 binding|NT4 binding|NT-4 binding|NT3 binding|neurotrophin 4/5 binding|NT-3 binding|neurotrophin TRKC receptor activity|neurotrophin TRKB receptor activity|neurotrophin 3 binding|neurotrophin TRKA receptor activity http://purl.obolibrary.org/obo/GO_0043121 GO:0008791 biolink:MolecularActivity arginine N-succinyltransferase activity Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine. RHEA:15185|MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN|EC:2.3.1.109 go-plus.json AOST activity|AstA|succinyl-CoA:L-arginine 2-N-succinyltransferase activity|arginine succinyltransferase activity|arginine and ornithine N2-succinyltransferase activity|AST activity|succinyl-CoA:L-arginine N2-succinyltransferase activity|arginine and ornithine N(2)-succinyltransferase activity http://purl.obolibrary.org/obo/GO_0008791 CHEBI:2288 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_2288 chebi_ph7_3 GO:0043128 biolink:BiologicalProcess positive regulation of 1-phosphatidylinositol 4-kinase activity Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase. go-plus.json up regulation of 1-phosphatidylinositol 4-kinase activity|positive regulation of PI4K activity|upregulation of 1-phosphatidylinositol 4-kinase activity|stimulation of 1-phosphatidylinositol 4-kinase activity|up-regulation of 1-phosphatidylinositol 4-kinase activity|activation of 1-phosphatidylinositol 4-kinase activity http://purl.obolibrary.org/obo/GO_0043128 GO:0018117 biolink:BiologicalProcess protein adenylylation The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid. go-plus.json protein adenylation|protein AMPylation|protein amino acid adenylylation http://purl.obolibrary.org/obo/GO_0018117 GO:0043127 biolink:BiologicalProcess negative regulation of 1-phosphatidylinositol 4-kinase activity Any process that stops or reduces the activity of the enzyme 1-phosphatidylinositol 4-kinase. go-plus.json downregulation of 1-phosphatidylinositol 4-kinase activity|down regulation of 1-phosphatidylinositol 4-kinase activity|inhibition of 1-phosphatidylinositol 4-kinase activity|negative regulation of PI4K activity|down-regulation of 1-phosphatidylinositol 4-kinase activity http://purl.obolibrary.org/obo/GO_0043127 GO:0018116 biolink:BiologicalProcess peptidyl-lysine adenylylation The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine. RESID:AA0227 go-plus.json peptidyl-lysine adenylation http://purl.obolibrary.org/obo/GO_0018116 GO:0018119 biolink:BiologicalProcess peptidyl-cysteine S-nitrosylation The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine. RESID:AA0230 go-plus.json protein S-nitrosylation|S-nitrosylation http://purl.obolibrary.org/obo/GO_0018119 GO:0018118 biolink:BiologicalProcess peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide. RESID:AA0229 go-plus.json peptidyl-L-cysteine glutathione disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide formation from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018118 GO:0043129 biolink:BiologicalProcess surfactant homeostasis Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli. go-plus.json http://purl.obolibrary.org/obo/GO_0043129 GO:0033732 biolink:MolecularActivity pyrroloquinoline-quinone synthase activity Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone. EC:1.3.3.11|RHEA:10692|KEGG_REACTION:R07353|MetaCyc:1.3.3.11-RXN go-plus.json PqqC|6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity http://purl.obolibrary.org/obo/GO_0033732 GO:0018113 biolink:MolecularActivity lysine racemase activity Catalysis of the reaction: L-lysine = D-lysine. MetaCyc:LYSINE-RACEMASE-RXN|RHEA:22864|EC:5.1.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0018113 GO:0033731 biolink:MolecularActivity arogenate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2. EC:1.3.1.79|MetaCyc:1.3.1.79-RXN go-plus.json L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity|arogenic dehydrogenase activity|pretyrosine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0033731 GO:0018112 biolink:MolecularActivity proline racemase activity Catalysis of the reaction: L-proline = D-proline. MetaCyc:PROLINE-RACEMASE-RXN|KEGG_REACTION:R01255|RHEA:10680|EC:5.1.1.4 go-plus.json http://purl.obolibrary.org/obo/GO_0018112 GO:0018115 biolink:BiologicalProcess peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine. RESID:AA0223 go-plus.json peptidyl-S-diphytanylglycerol diether-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine synthesis from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018115 GO:0033730 biolink:MolecularActivity arogenate dehydrogenase (NADP+) activity Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2. EC:1.3.1.78|RHEA:15417|MetaCyc:1.3.1.78-RXN go-plus.json TyrAa|TyrAAT2|arogenic dehydrogenase activity|TyrAAT1|pretyrosine dehydrogenase activity|L-arogenate:NADP+ oxidoreductase (decarboxylating) activity http://purl.obolibrary.org/obo/GO_0033730 GO:0018114 biolink:MolecularActivity threonine racemase activity Catalysis of the reaction: L-threonine = D-threonine. MetaCyc:THREONINE-RACEMASE-RXN|RHEA:13913|KEGG_REACTION:R01467|EC:5.1.1.6 go-plus.json http://purl.obolibrary.org/obo/GO_0018114 GO:0018111 biolink:MolecularActivity methionine racemase activity Catalysis of the reaction: L-methionine = D-methionine. KEGG_REACTION:R00655|MetaCyc:METHIONINE-RACEMASE-RXN|RHEA:12492|EC:5.1.1.2 go-plus.json http://purl.obolibrary.org/obo/GO_0018111 GO:0018110 biolink:MolecularActivity histone arginine kinase activity Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+). EC:2.7.3.- go-plus.json histone-arginine kinase activity http://purl.obolibrary.org/obo/GO_0018110 GO:0033729 biolink:MolecularActivity anthocyanidin reductase activity Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+. MetaCyc:1.3.1.77-RXN|EC:1.3.1.77 go-plus.json AtANR|ANR|MtANR|flavan-3-ol:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033729 GO:0033728 biolink:MolecularActivity divinyl chlorophyllide a 8-vinyl-reductase activity Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+. MetaCyc:RXN-5286|EC:1.3.1.75|RHEA:14449 go-plus.json chlorophyllide-a:NADP+ oxidoreductase activity|[4-vinyl]chlorophyllide a reductase activity|4VCR http://purl.obolibrary.org/obo/GO_0033728 GO:0033727 biolink:MolecularActivity aldehyde dehydrogenase (FAD-independent) activity Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor. MetaCyc:1.2.99.3-RXN|MetaCyc:CARBOXYLATE-REDUCTASE-RXN|EC:1.2.99.7|MetaCyc:1.2.99.7-RXN go-plus.json aldehyde oxidoreductase activity|Mop|aldehyde:acceptor oxidoreductase (FAD-independent) activity|AORDd http://purl.obolibrary.org/obo/GO_0033727 GO:0033726 biolink:MolecularActivity aldehyde ferredoxin oxidoreductase activity Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin. EC:1.2.7.5|RHEA:16421|MetaCyc:1.2.7.5-RXN go-plus.json AOR|aldehyde:ferredoxin oxidoreductase activity|tungsten-containing aldehyde ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033726 GO:0008769 biolink:MolecularActivity obsolete X-His dipeptidase activity OBSOLETE. Catalysis of the hydrolysis of Xaa-His dipeptides. EC:3.4.13.3|MetaCyc:3.4.13.3-RXN go-plus.json aminoacyl-histidine dipeptidase activity|homocarnosinase activity|dipeptidase M|aminoacylhistidine dipeptidase activity|X-His dipeptidase activity|Xaa-His dipeptidase activity|carnosinase activity http://purl.obolibrary.org/obo/GO_0008769 GO:0033725 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033725 GO:0033724 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033724 GO:0008768 biolink:MolecularActivity UDP-sugar diphosphatase activity Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate. EC:3.6.1.45|Reactome:R-HSA-6810464|MetaCyc:UDPSUGARHYDRO-RXN go-plus.json UDP-sugar pyrophosphatase activity|nucleosidediphosphate-sugar pyrophosphatase activity|nucleosidediphosphate-sugar diphosphatase activity|UDP-sugar sugarphosphohydrolase activity|UDP-sugar hydrolase activity http://purl.obolibrary.org/obo/GO_0008768 GO:0008767 biolink:MolecularActivity UDP-galactopyranose mutase activity Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose. EC:5.4.99.9|MetaCyc:GALPMUT-RXN|RHEA:24132 go-plus.json UDP-D-galactopyranose furanomutase activity|UDPgalactopyranose mutase activity http://purl.obolibrary.org/obo/GO_0008767 GO:0033723 biolink:MolecularActivity fluoroacetaldehyde dehydrogenase activity Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+. RHEA:16677|EC:1.2.1.69 go-plus.json fluoroacetaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033723 UBERON:0005705 biolink:AnatomicalEntity primary palate mesenchyme Mesenchyme that is part of a developing primary palate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005705 GO:0008766 biolink:MolecularActivity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine. MetaCyc:UDP-NACMURALGLDAPAALIG-RXN|EC:6.3.2.10|RHEA:28374 go-plus.json http://purl.obolibrary.org/obo/GO_0008766 UBERON:0005704 biolink:AnatomicalEntity secondary palatal shelf mesenchyme Mesenchyme that is part of a developing secondary palatal shelf. go-plus.json palatal shelf mesenchyme http://purl.obolibrary.org/obo/UBERON_0005704 GO:0033722 biolink:MolecularActivity malonate-semialdehyde dehydrogenase activity Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+. EC:1.2.1.15|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDROGENASE-RXN go-plus.json malonic semialdehyde dehydrogenase activity|3-oxopropanoate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033722 GO:0008765 biolink:MolecularActivity UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate. MetaCyc:UDP-NACMURALGLDAPLIG-RXN|KEGG_REACTION:R02788|EC:6.3.2.13|RHEA:23676 go-plus.json UDP-N-acetylmuramyl-tripeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity|MurE synthetase activity http://purl.obolibrary.org/obo/GO_0008765 GO:0043135 biolink:MolecularActivity 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+. MetaCyc:RXN-10969 go-plus.json PRPP pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0043135 GO:0008764 biolink:MolecularActivity UDP-N-acetylmuramoylalanine-D-glutamate ligase activity Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. MetaCyc:UDP-NACMURALA-GLU-LIG-RXN|EC:6.3.2.9|RHEA:16429|KEGG_REACTION:R02783 go-plus.json MurD synthetase activity|UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)|D-glutamate ligase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity|UDP-Mur-NAC-L-Ala:D-Glu ligase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity|D-glutamate-adding enzyme activity http://purl.obolibrary.org/obo/GO_0008764 GO:0043134 biolink:BiologicalProcess regulation of hindgut contraction Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0043134 GO:0008763 biolink:MolecularActivity UDP-N-acetylmuramate-L-alanine ligase activity Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine. MetaCyc:UDP-NACMUR-ALA-LIG-RXN|EC:6.3.2.8|RHEA:23372|KEGG_REACTION:R03193 go-plus.json UDP-N-acetylmuramoyl-L-alanine synthetase activity|L-Ala ligase activity|UDP-acetylmuramyl-L-alanine synthetase activity|L-alanine-adding enzyme activity|alanine-adding enzyme activity|UDP-N-acetylmuramoylalanine synthetase activity|uridine diphospho-N-acetylmuramoylalanine synthetase activity|uridine diphosphate N-acetylmuramate:L-alanine ligase activity|uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity|UDP-N-acetylmuramyl:L-alanine ligase activity|uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity|MurC synthetase activity|UDPMurNAc-L-alanine synthetase activity|UDP-MurNAc:L-alanine ligase activity|UDP-N-acetylmuramate:L-alanine ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0008763 GO:0043137 biolink:BiologicalProcess DNA replication, removal of RNA primer Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. go-plus.json Okazaki initiator RNA removal http://purl.obolibrary.org/obo/GO_0043137 GO:0008762 biolink:MolecularActivity UDP-N-acetylmuramate dehydrogenase activity Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+. MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN|EC:1.3.1.98|RHEA:12248 go-plus.json UDP-N-acetylenolpyruvoylglucosamine reductase activity|uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity|UDP-GlcNAc-enoylpyruvate reductase activity|UDP-N-acetylmuramate:NADP+ oxidoreductase activity|MurB reductase|UDP-N-acetylglucosamine-enoylpyruvate reductase activity|uridine diphosphoacetylpyruvoylglucosamine reductase activity|uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008762 GO:0043136 biolink:MolecularActivity glycerol-3-phosphatase activity Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate. Reactome:R-HSA-8955794|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0043136 GO:0008761 biolink:MolecularActivity UDP-N-acetylglucosamine 2-epimerase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine. Reactome:R-HSA-4088338|EC:5.1.3.14|MetaCyc:UDPGLCNACEPIM-RXN|RHEA:17213|Reactome:R-HSA-4085021 go-plus.json UDP-GlcNAc-2-epimerase activity|UDP-N-acetylglucosamine 2'-epimerase activity|UDP-N-acetyl-D-glucosamine 2-epimerase activity|uridine diphospho-N-acetylglucosamine 2'-epimerase activity|uridine diphosphate-N-acetylglucosamine-2'-epimerase activity|uridine diphosphoacetylglucosamine 2'-epimerase activity http://purl.obolibrary.org/obo/GO_0008761 GO:0043131 biolink:BiologicalProcess erythrocyte enucleation The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation. go-plus.json http://purl.obolibrary.org/obo/GO_0043131 GO:0043130 biolink:MolecularActivity ubiquitin binding Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. Reactome:R-HSA-983152|Reactome:R-HSA-1169404|Reactome:R-HSA-205008 go-plus.json http://purl.obolibrary.org/obo/GO_0043130 GO:0008760 biolink:MolecularActivity UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine. KEGG_REACTION:R00660|EC:2.5.1.7|MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN|RHEA:18681 go-plus.json MurA transferase activity|UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity|phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity|phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity|phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity|phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity|enoylpyruvate transferase activity|pyruvate-uridine diphospho-N-acetylglucosamine transferase activity|pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity|phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity|pyruvate-UDP-acetylglucosamine transferase activity|phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity|pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine enoylpyruvyltransferase activity http://purl.obolibrary.org/obo/GO_0008760 GO:0043133 biolink:BiologicalProcess hindgut contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0043133 GO:0043132 biolink:BiologicalProcess NAD transport The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH. go-plus.json reduced nicotinamide adenine dinucleotide transport|reduced NAD transport|oxidized nicotinamide adenine dinucleotide transport|oxidized NAD transport|NAD (reduced) transport|NAD (oxidized) transport|NADH transport|nicotinamide adenine dinucleotide transport http://purl.obolibrary.org/obo/GO_0043132 GO:0043139 biolink:MolecularActivity 5'-3' DNA helicase activity Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis. Reactome:R-HSA-6782131 go-plus.json ATP-dependent 5'-3' DNA helicase activity|DNA helicase IV activity|ATP-dependent 5' to 3' DNA helicase activity|5' to 3' DNA helicase activity http://purl.obolibrary.org/obo/GO_0043139 GO:0043138 biolink:MolecularActivity 3'-5' DNA helicase activity Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis. Reactome:R-HSA-9684118|Reactome:R-HSA-75949|Reactome:R-HSA-9613498|Reactome:R-HSA-167097|Reactome:R-HSA-9613490|Reactome:R-HSA-9613494|Reactome:R-HSA-174438|Reactome:R-HSA-9613497 go-plus.json ATP-dependent 3' to 5' DNA helicase activity|ATP-dependent 3'-5' DNA helicase activity|3' to 5' DNA helicase activity http://purl.obolibrary.org/obo/GO_0043138 CHEBI:138429 biolink:ChemicalSubstance isopimarane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138429 GO:0033721 biolink:MolecularActivity aldehyde dehydrogenase (NADP+) activity Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+. EC:1.2.1.4|RHEA:11888|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN go-plus.json NADP-acetaldehyde dehydrogenase activity|NADP-dependent aldehyde dehydrogenase activity|aldehyde:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033721 GO:0033720 biolink:MolecularActivity (S)-mandelate dehydrogenase activity Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor. EC:1.1.99.31|RHEA:15749|UM-BBD_reactionID:r1048|MetaCyc:MANDELATE-DEHYDROGENASE-RXN|MetaCyc:MANDELATE-OXY-RXN go-plus.json MDH|L(+)-mandelate dehydrogenase activity|(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033720 UBERON:0005712 biolink:AnatomicalEntity midgut duodenum mesentery A mesentery of duodenum that is part of a midgut. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005712 UBERON:0005711 biolink:AnatomicalEntity foregut duodenum mesentery A mesentery of duodenum that is part of a foregut. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005711 GO:0033718 biolink:MolecularActivity pyranose dehydrogenase (acceptor) activity Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor. MetaCyc:RXN-7966|MetaCyc:RXN-7965|MetaCyc:RXN-7963|MetaCyc:RXN-7962|MetaCyc:RXN-7961|EC:1.1.99.29 go-plus.json pyranose dehydrogenase activity|quinone-dependent pyranose dehydrogenase activity|pyranose-quinone oxidoreductase activity|pyranose:acceptor oxidoreductase activity|PDH http://purl.obolibrary.org/obo/GO_0033718 GO:0033717 biolink:MolecularActivity gluconate 2-dehydrogenase (acceptor) activity Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor. EC:1.1.99.3|MetaCyc:GLUCONATE-2-DEHYDROGENASE-RXN|RHEA:12769 go-plus.json gluconic acid dehydrogenase activity|D-gluconate dehydrogenase activity|D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity|gluconate oxidase activity|2-ketogluconate reductase activity|D-gluconate:(acceptor) 2-oxidoreductase activity|gluconic dehydrogenase activity|D-gluconate:acceptor 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033717 GO:0043140 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043140 GO:0033716 biolink:MolecularActivity nucleoside oxidase (hydrogen peroxide-forming) activity Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide. EC:1.1.3.39|RHEA:15489|MetaCyc:1.1.3.39-RXN go-plus.json nucleoside:oxygen 5'-oxidoreductase (hydrogen peroxide-forming) activity http://purl.obolibrary.org/obo/GO_0033716 GO:0033715 biolink:MolecularActivity nucleoside oxidase activity Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O. EC:1.1.3.28|RHEA:28651|MetaCyc:NUCLEOSIDE-OXIDASE-RXN go-plus.json nucleoside:oxygen 5'-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033715 GO:0033714 biolink:MolecularActivity secondary-alcohol oxidase activity Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone. EC:1.1.3.18|KEGG_REACTION:R02277|RHEA:23180|MetaCyc:SECONDARY-ALCOHOL-OXIDASE-RXN go-plus.json secondary-alcohol:oxygen oxidoreductase activity|secondary alcohol oxidase activity|polyvinyl alcohol oxidase activity http://purl.obolibrary.org/obo/GO_0033714 GO:0008779 biolink:MolecularActivity acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine. EC:2.3.1.40|MetaCyc:ACYLGPEACYLTRANS-RXN|RHEA:10304 go-plus.json acyl-ACP-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity|acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0008779 GO:0033713 biolink:MolecularActivity choline:oxygen 1-oxidoreductase activity Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide. EC:1.1.3.17|RHEA:13505|MetaCyc:CHOLINE-OXIDASE-RXN go-plus.json choline oxidase activity http://purl.obolibrary.org/obo/GO_0033713 GO:0033712 biolink:MolecularActivity 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH. EC:1.1.1.292|RHEA:24208|KEGG_REACTION:R08194|MetaCyc:1.1.1.292-RXN go-plus.json 1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity|AFR http://purl.obolibrary.org/obo/GO_0033712 GO:0008778 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008778 GO:0008777 biolink:MolecularActivity acetylornithine deacetylase activity Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine. RHEA:15941|MetaCyc:ACETYLORNDEACET-RXN|EC:3.5.1.16 go-plus.json acetylornithinase activity|N-acetylornithinase activity|N2-acetyl-L-ornithine amidohydrolase activity|2-N-acetyl-L-ornithine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0008777 GO:0033711 biolink:MolecularActivity 4-phosphoerythronate dehydrogenase activity Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH. EC:1.1.1.290|MetaCyc:ERYTHRON4PDEHYDROG-RXN|RHEA:18829|KEGG_REACTION:R04210 go-plus.json erythronate-4-phosphate dehydrogenase activity|4-O-phosphoerythronate dehydrogenase activity|PdxB|PdxB 4PE dehydrogenase activity|4PE dehydrogenase activity|4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033711 GO:0008776 biolink:MolecularActivity acetate kinase activity Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate. RHEA:11352|EC:2.7.2.1|MetaCyc:ACETATEKIN-RXN go-plus.json ATP:acetate phosphotransferase activity|AK activity|acetate kinase (phosphorylating) activity|AckA|acetic kinase activity|acetokinase activity http://purl.obolibrary.org/obo/GO_0008776 GO:0043146 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043146 GO:0008775 biolink:MolecularActivity acetate CoA-transferase activity Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA. RHEA:13381|MetaCyc:ACECOATRANS-RXN|Reactome:R-HSA-2066788|UM-BBD_enzymeID:e0012|EC:2.8.3.8 go-plus.json butyryl CoA:acetate CoA transferase activity|succinyl-CoA:acetate CoA transferase activity|acetate coenzyme A-transferase activity|butyryl coenzyme A transferase activity|acetyl-CoA:acetoacetate CoA transferase activity|acyl-CoA:acetate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0008775 GO:0043145 biolink:BiologicalProcess sno(s)RNA 3'-end cleavage The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional. go-plus.json sRNA 3'-end cleavage|snoRNA 3'-end cleavage|sno(s)RNA 3' end cleavage http://purl.obolibrary.org/obo/GO_0043145 GO:0043148 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043148 GO:0008774 biolink:MolecularActivity acetaldehyde dehydrogenase (acetylating) activity Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+. MetaCyc:ACETALD-DEHYDROG-RXN|RHEA:23288|EC:1.2.1.10 go-plus.json acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)|aldehyde dehydrogenase (acylating) activity|acylating acetaldehyde dehydrogenase activity|DmpF|ADA http://purl.obolibrary.org/obo/GO_0008774 PR:000020497 biolink:Protein lactotransferrin proteolytic cleavage product A lactotransferrin that has been processed by proteolytic cleavage. go-plus.json LTF/ClvPrd http://purl.obolibrary.org/obo/PR_000020497 GO:0043147 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043147 GO:0008773 biolink:MolecularActivity [protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII). EC:2.7.7.59|MetaCyc:URITRANS-RXN|RHEA:13673 go-plus.json uridyl removing enzyme|UTP:protein-PII uridylyltransferase activity|PII uridylyl-transferase activity|protein-PII uridylyltransferase activity|UTP:[protein-PII] uridylyltransferase activity|uridylyl removing enzyme activity http://purl.obolibrary.org/obo/GO_0008773 GO:0008772 biolink:MolecularActivity [isocitrate dehydrogenase (NADP+)] kinase activity Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate. RHEA:43540|MetaCyc:PHOSICITDEHASE-RXN|EC:2.7.11.5 go-plus.json IDH kinase/phosphatase activity|isocitrate dehydrogenase (NADP) kinase activity|isocitrate dehydrogenase (NADP+) kinase activity|IDH-K/P|ICDH kinase/phosphatase activity|isocitrate dehydrogenase kinase activity|isocitrate dehydrogenase kinase/phosphatase activity|ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity|isocitrate dehydrogenase kinase (phosphorylating) activity|IDHK/P|IDH kinase activity http://purl.obolibrary.org/obo/GO_0008772 GO:0043142 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043142 GO:0008771 biolink:MolecularActivity [citrate (pro-3S)-lyase] ligase activity Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form). MetaCyc:CITC-RXN|KEGG_REACTION:R04449|RHEA:23788|EC:6.2.1.22 go-plus.json acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)|acetate: SH-acyl-carrier-protein enzyme ligase (AMP)|citrate lyase synthetase activity|citrate lyase ligase activity|citrate (pro-3S)-lyase ligase activity|acetate:HS-citrate lyase ligase activity http://purl.obolibrary.org/obo/GO_0008771 GO:0043141 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043141 GO:0008770 biolink:MolecularActivity [acyl-carrier-protein] phosphodiesterase activity Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein. MetaCyc:3.1.4.14-RXN|RHEA:20537|EC:3.1.4.14 go-plus.json holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity|ACP hydrolyase activity|ACP phosphodiesterase activity|[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity|AcpH|acyl-carrier-protein phosphodiesterase activity|[acyl-carrier protein] phosphodiesterase activity|acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008770 GO:0043144 biolink:BiologicalProcess sno(s)RNA processing Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea). go-plus.json http://purl.obolibrary.org/obo/GO_0043144 goslim_yeast GO:0033719 biolink:MolecularActivity 2-oxo-acid reductase activity Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor. MetaCyc:1.1.99.30-RXN|EC:1.1.99.30|RHEA:23664 go-plus.json (2R)-hydroxy-carboxylate:acceptor oxidoreductase activity|HVOR|(2R)-hydroxycarboxylate-viologen-oxidoreductase activity|2-oxoacid reductase activity http://purl.obolibrary.org/obo/GO_0033719 GO:0043143 biolink:BiologicalProcess regulation of translation by machinery localization Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of translational protein localization|translational machinery localization|translational protein localization|establishment and maintenance of translational machinery localization|regulation of translation by machinery localisation http://purl.obolibrary.org/obo/GO_0043143 CHEBI:138437 biolink:ChemicalSubstance (S)-3-hydroxytetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138437 chebi_ph7_3 CHEBI:138436 biolink:ChemicalSubstance hexadecanoyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138436 chebi_ph7_3 GO:0043149 biolink:BiologicalProcess stress fiber assembly The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity. go-plus.json actin cable assembly|stress fibre biosynthesis|actin cable formation|stress fibre formation http://purl.obolibrary.org/obo/GO_0043149 CHEBI:138439 biolink:ChemicalSubstance [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138439 chebi_ph7_3 GO:0033710 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033710 CHEBI:138430 biolink:ChemicalSubstance (9R,13R)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138430 chebi_ph7_3 UBERON:0005702 biolink:AnatomicalEntity optic eminence mesenchyme Mesenchyme that is part of a optic eminence. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005702 CHEBI:138434 biolink:ChemicalSubstance 6-{(1S,5S)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}hexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138434 CHEBI:138433 biolink:ChemicalSubstance (9S,13S)-1a,1b-dinor-12-oxo-10,15-phytodienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138433 chebi_ph7_3 CHEBI:138432 biolink:ChemicalSubstance 6-{(1S,5S)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}hexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138432 chebi_ph7_3 CHEBI:138431 biolink:ChemicalSubstance (9S,13S)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138431 chebi_ph7_3 CHEBI:44395 biolink:ChemicalSubstance N-acetyl-beta-D-galactosamine 6-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44395 GO:0033707 biolink:MolecularActivity 3''-deamino-3''-oxonicotianamine reductase activity Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+. MetaCyc:1.1.1.285-RXN|EC:1.1.1.285 go-plus.json 2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033707 GO:0033706 biolink:MolecularActivity obsolete quinate/shikimate dehydrogenase activity OBSOLETE. Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+, and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+. go-plus.json quinate/shikimate dehydrogenase activity|L-quinate:NAD(P)+ 3-oxidoreductase activity|YdiB http://purl.obolibrary.org/obo/GO_0033706 GO:0033705 biolink:MolecularActivity GDP-4-dehydro-6-deoxy-D-mannose reductase activity Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN|EC:1.1.1.281 go-plus.json GDP-6-deoxy-D-lyxo-4-hexulose reductase activity|GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity|Rmd|GDP-4-keto-6-deoxy-D-mannose reductase activity http://purl.obolibrary.org/obo/GO_0033705 GO:0008749 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008749 GO:0043151 biolink:BiologicalProcess DNA synthesis involved in double-strand break repair via single-strand annealing The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing. go-plus.json DNA synthesis during double-strand break repair via single-strand annealing http://purl.obolibrary.org/obo/GO_0043151 GO:0008748 biolink:MolecularActivity N-ethylmaleimide reductase activity Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+. MetaCyc:RXN0-5101|RHEA:35523 go-plus.json http://purl.obolibrary.org/obo/GO_0008748 GO:0033704 biolink:MolecularActivity 3beta-hydroxy-5alpha-steroid dehydrogenase activity Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH. KEGG_REACTION:R07138|RHEA:18137|MetaCyc:1.1.1.278-RXN|EC:1.1.1.278 go-plus.json 3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033704 GO:0043150 biolink:BiologicalProcess DNA synthesis involved in double-strand break repair via homologous recombination The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination. go-plus.json DNA synthesis during double-strand break repair via homologous recombination http://purl.obolibrary.org/obo/GO_0043150 GO:0008747 biolink:MolecularActivity N-acetylneuraminate lyase activity Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate. MetaCyc:ACNEULY-RXN|KEGG_REACTION:R01811|Reactome:R-HSA-4085217|RHEA:23296|EC:4.1.3.3 go-plus.json N-acetylneuraminate aldolase activity|sialate lyase activity|N-acetylneuraminate pyruvate-lyase activity|acetylneuraminate pyruvate-lyase activity|NALase activity|sialic acid aldolase activity|N-acetylneuraminic aldolase activity|neuraminic aldolase activity|N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)|neuraminic acid aldolase activity|N-acetylneuraminic acid lyase activity|N-acetylneuraminic acid aldolase activity|sialic aldolase activity|NPL|N-acetylneuraminic lyase activity|NANA lyase activity|acetylneuraminate lyase activity|neuraminate aldolase activity http://purl.obolibrary.org/obo/GO_0008747 GO:0033703 biolink:MolecularActivity 3beta-hydroxy-5beta-steroid dehydrogenase activity Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH. KEGG_REACTION:R06166|MetaCyc:1.1.1.277-RXN|EC:1.1.1.277|RHEA:22944 go-plus.json 3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity|3beta-hydroxysteroid 5beta-oxidoreductase activity|3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033703 GO:0008746 biolink:MolecularActivity NAD(P)+ transhydrogenase activity Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. EC:1.6.1.1|Reactome:R-HSA-450971|KEGG_REACTION:R00112|RHEA:11692 go-plus.json H+-thase|NADH transhydrogenase|energy-linked transhydrogenase|NADPH-NAD oxidoreductase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|NADH-NADP-transhydrogenase|NADPH:NAD+ transhydrogenase|NADPH-NAD transhydrogenase|pyridine nucleotide transferase|NAD transhydrogenase http://purl.obolibrary.org/obo/GO_0008746 GO:0033702 biolink:MolecularActivity (+)-trans-carveol dehydrogenase activity Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH. KEGG_REACTION:R06117|EC:1.1.1.275|RHEA:14825|MetaCyc:RXN-9397 go-plus.json (+)-trans-carveol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033702 GO:0033701 biolink:MolecularActivity dTDP-galactose 6-dehydrogenase activity Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+. MetaCyc:DTDP-GALACTOSE-6-DEHYDROGENASE-RXN|RHEA:12396|EC:1.1.1.186 go-plus.json dTDPgalactose 6-dehydrogenase activity|thymidine-diphosphate-galactose dehydrogenase activity|dTDP-D-galactose:NADP+ 6-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033701 GO:0008745 biolink:MolecularActivity N-acetylmuramoyl-L-alanine amidase activity Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides. Reactome:R-HSA-6799977|EC:3.5.1.28|MetaCyc:3.5.1.28-RXN go-plus.json acetylmuramyl-L-alanine amidase activity|N-acetylmuramyl-L-alanine amidase activity|acetylmuramyl-alanine amidase activity|N-acetylmuramylalanine amidase activity|N-acetylmuramoyl-L-alanine amidase type II|acetylmuramoyl-alanine amidase activity|N-acylmuramyl-L-alanine amidase activity|N-acetylmuramoyl-L-alanine amidase type I|N-acetylmuramic acid L-alanine amidase activity http://purl.obolibrary.org/obo/GO_0008745 GO:0008744 biolink:MolecularActivity L-xylulokinase activity Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate. MetaCyc:LYXK-RXN|RHEA:18869|EC:2.7.1.53 go-plus.json L-xylulokinase (phosphorylating)|L-xylulose kinase activity|ATP:L-xylulose 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008744 GO:0033700 biolink:BiologicalProcess phospholipid efflux The directed movement of a phospholipid out of a cell or organelle. go-plus.json phospholipid export http://purl.obolibrary.org/obo/GO_0033700 GO:0008743 biolink:MolecularActivity L-threonine 3-dehydrogenase activity Catalysis of the reaction: L-threonine + NAD(+) = L-2-amino-3-oxobutanoate + CO(2) + NADH. RHEA:13161|EC:1.1.1.103|MetaCyc:THREODEHYD-RXN|KEGG_REACTION:R01465|Reactome:R-HSA-6798667 go-plus.json L-threonine:NAD+ oxidoreductase activity|threonine 3-dehydrogenase activity|L-threonine dehydrogenase activity|threonine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008743 GO:0043157 biolink:BiologicalProcess response to cation stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0043157 GO:0043156 biolink:BiologicalProcess obsolete chromatin remodeling in response to cation stress OBSOLETE. Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0043156 GO:0008742 biolink:MolecularActivity L-ribulose-phosphate 4-epimerase activity Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate. RHEA:22368|MetaCyc:RIBULPEPIM-RXN|KEGG_REACTION:R05850|EC:5.1.3.4 go-plus.json phosphoribulose isomerase activity|ribulose phosphate 4-epimerase activity|AraD|L-ribulose-5-phosphate 4-epimerase|L-ru5P activity|L-ribulose 5-phosphate 4-epimerase activity|L-Ru5P http://purl.obolibrary.org/obo/GO_0008742 GO:0008741 biolink:MolecularActivity ribulokinase activity Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. EC:2.7.1.16|MetaCyc:RIBULOKIN-RXN|RHEA:22072 go-plus.json L-ribulokinase activity|ribulokinase (phosphorylating)|ATP:L(or D)-ribulose 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008741 GO:0043159 biolink:CellularComponent acrosomal matrix A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0043159 GO:0008740 biolink:MolecularActivity L-rhamnose isomerase activity Catalysis of the reaction: L-rhamnose = L-rhamnulose. MetaCyc:RHAMNISOM-RXN|KEGG_REACTION:R02437|EC:5.3.1.14|RHEA:23160 go-plus.json rhamnose isomerase activity|L-rhamnose aldose-ketose-isomerase activity|L-rhamnose ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0008740 GO:0043158 biolink:BiologicalProcess heterocyst differentiation The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen. go-plus.json heterocyst formation|heterocyst biosynthesis|heterocyst cell differentiation http://purl.obolibrary.org/obo/GO_0043158 GO:0043153 biolink:BiologicalProcess entrainment of circadian clock by photoperiod The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night). go-plus.json photoentrainment of circadian clock http://purl.obolibrary.org/obo/GO_0043153 GO:0043152 biolink:BiologicalProcess induction of bacterial agglutination Any process in which infecting bacteria are clumped together by a host organism. go-plus.json http://purl.obolibrary.org/obo/GO_0043152 GO:0043155 biolink:BiologicalProcess negative regulation of photosynthesis, light reaction Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis. go-plus.json down regulation of photosynthesis, light reaction|inhibition of photosynthesis, light reaction|down-regulation of photosynthesis, light reaction|downregulation of photosynthesis, light reaction http://purl.obolibrary.org/obo/GO_0043155 GO:0033709 biolink:MolecularActivity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+. KEGG_REACTION:R07144|MetaCyc:RXN-7972|RHEA:11868 go-plus.json D-arabinitol dehydrogenase 1 activity|D-arabinitol:NADP+ dehydrogenase activity|ARD1p|NADP+-dependent D-arabinitol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0033709 GO:0043154 biolink:BiologicalProcess negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process. go-plus.json down-regulation of caspase activity|inhibition of caspase activation|downregulation of caspase activity|negative regulation of caspase activity|down regulation of caspase activity|inhibition of caspase activity|negative regulation of caspase activation http://purl.obolibrary.org/obo/GO_0043154 GO:0033708 biolink:MolecularActivity isocitrate-homoisocitrate dehydrogenase activity Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+. EC:1.1.1.286|MetaCyc:RXN-7969 go-plus.json PH1722|homoisocitrate-isocitrate dehydrogenase activity|isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity http://purl.obolibrary.org/obo/GO_0033708 CHEBI:138405 biolink:ChemicalSubstance O-(S-(7Z)-tetradecenoylpantetheine-4'-phosphoryl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138405 chebi_ph7_3 CHEBI:138404 biolink:ChemicalSubstance (E)-hex-4-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138404 chebi_ph7_3 CHEBI:138403 biolink:ChemicalSubstance O-[S-(2E,9Z)-hexadecadienoylpantetheine-4'-phosphoryl]-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138403 chebi_ph7_3 CHEBI:138402 biolink:ChemicalSubstance 4,4'-disulfanyldibutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138402 CHEBI:138408 biolink:ChemicalSubstance isoprostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_138408 CHEBI:138407 biolink:ChemicalSubstance O-[S-(3R)-hydroxy-(9Z)-hexadecenoylpantetheine-4'-phosphoryl]-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138407 chebi_ph7_3 CHEBI:138406 biolink:ChemicalSubstance O-{S-[(9Z)-3-oxohexadecenoylpantetheine]-4'-phosphoryl}-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138406 chebi_ph7_3 CHEBI:138401 biolink:ChemicalSubstance 3alpha,7beta-dihydroxy-12-oxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138401 CHEBI:138400 biolink:ChemicalSubstance 4-sulfanylbutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138400 GO:0043160 biolink:CellularComponent acrosomal lumen The volume enclosed within the acrosome membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0043160 GO:0043162 biolink:BiologicalProcess ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. go-plus.json ubiquitin-dependent protein catabolic process via the MVB pathway|ubiquitin-dependent protein breakdown via the multivesicular body pathway|ubiquitin-dependent protein catabolism via the MVB pathway|ubiquitin-dependent protein degradation via the multivesicular body pathway http://purl.obolibrary.org/obo/GO_0043162 GO:0043161 biolink:BiologicalProcess proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go-plus.json proteasomal ubiquitin-dependent protein degradation|proteasomal pathway|proteasomal ubiquitin-dependent protein breakdown|proteasome pathway|proteasomal ubiquitin-dependent protein catabolic process|proteasomal processing|proteasomal ubiquitin-dependent protein catabolism http://purl.obolibrary.org/obo/GO_0043161 GO:0008759 biolink:MolecularActivity UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine. EC:3.5.1.108 go-plus.json http://purl.obolibrary.org/obo/GO_0008759 GO:0008758 biolink:MolecularActivity UDP-2,3-diacylglucosamine hydrolase activity Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP. RHEA:25213|MetaCyc:LIPIDXSYNTHESIS-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008758 GO:0008757 biolink:MolecularActivity S-adenosylmethionine-dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. go-plus.json S-adenosyl methionine-dependent methyltransferase activity|SAM-dependent methyltransferase activity http://purl.obolibrary.org/obo/GO_0008757 GO:0008756 biolink:MolecularActivity o-succinylbenzoate-CoA ligase activity Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate. EC:6.2.1.26|RHEA:17009|KEGG_REACTION:R04030|MetaCyc:O-SUCCINYLBENZOATE-COA-LIG-RXN go-plus.json OSB-CoA synthetase activity|o-succinylbenzoyl-CoA synthetase activity|o-succinylbenzoyl-coenzyme A synthetase activity|2-succinylbenzoate:CoA ligase (AMP-forming)|o-succinylbenzoate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0008756 GO:0008755 biolink:MolecularActivity O antigen polymerase activity Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide. go-plus.json O-antigen polymerase activity http://purl.obolibrary.org/obo/GO_0008755 GO:0043168 biolink:MolecularActivity anion binding Binding to an anion, a charged atom or group of atoms with a net negative charge. go-plus.json http://purl.obolibrary.org/obo/GO_0043168 GO:0008754 biolink:MolecularActivity O antigen ligase activity Catalysis of the reaction: Lipid A-core + colanic acid = MLPS. MetaCyc:RXN0-5294 go-plus.json http://purl.obolibrary.org/obo/GO_0008754 GO:0043167 biolink:MolecularActivity ion binding Binding to an ion, a charged atoms or groups of atoms. go-plus.json atom binding http://purl.obolibrary.org/obo/GO_0043167 goslim_pir|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast GO:0008753 biolink:MolecularActivity NADPH dehydrogenase (quinone) activity Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol. KEGG_REACTION:R07359|EC:1.6.5.10|MetaCyc:NADPH-DEHYDROGENASE-QUINONE-RXN|RHEA:46164 go-plus.json NADPH:(quinone-acceptor) oxidoreductase|reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase|NADPH oxidase http://purl.obolibrary.org/obo/GO_0008753 GO:0008752 biolink:MolecularActivity FMN reductase activity Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+. EC:1.5.1.39 go-plus.json riboflavine mononucleotide reductase activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity|NAD(P)H2 dehydrogenase (FMN)|SsuE|NAD(P)H(2):FMN oxidoreductase activity|FMNH2:NAD(P)+ oxidoreductase activity|NAD(P)H(2) dehydrogenase (FMN) activity|NAD(P)H dehydrogenase (FMN) activity|NAD(P)H2:FMN oxidoreductase activity|flavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H-dependent FMN reductase activity|NAD(P)H-FMN reductase activity|NAD(P)H:flavin oxidoreductase activity|riboflavin mononucleotide reductase activity http://purl.obolibrary.org/obo/GO_0008752 GO:0043169 biolink:MolecularActivity cation binding Binding to a cation, a charged atom or group of atoms with a net positive charge. go-plus.json http://purl.obolibrary.org/obo/GO_0043169 GO:0008751 biolink:MolecularActivity obsolete NAD(P)H dehydrogenase OBSOLETE. (Was not defined before being made obsolete). go-plus.json NAD(P)H dehydrogenase http://purl.obolibrary.org/obo/GO_0008751 GO:0043164 biolink:BiologicalProcess Gram-negative-bacterium-type cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. go-plus.json 1-2nm peptidoglycan-based cell wall biogenesis|cell wall biosynthetic process|cell wall anabolism|cell wall assembly|cell wall synthesis|cell wall formation http://purl.obolibrary.org/obo/GO_0043164 GO:0008750 biolink:MolecularActivity NAD(P)+ transhydrogenase (AB-specific) activity Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+. MetaCyc:1.6.1.2-RXN|EC:1.6.1.2 go-plus.json NAD(P) transhydrogenase (AB-specific) activity|transhydrogenase activity|NADPH:NAD+ oxidoreductase (AB-specific)|pyridine nucleotide transhydrogenase activity http://purl.obolibrary.org/obo/GO_0008750 GO:0043163 biolink:BiologicalProcess cell envelope organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present. go-plus.json cell envelope organization and biogenesis|cell envelope organisation http://purl.obolibrary.org/obo/GO_0043163 goslim_pir GO:0043166 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043166 GO:0043165 biolink:BiologicalProcess Gram-negative-bacterium-type cell outer membrane assembly The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures. go-plus.json cell outer membrane biogenesis http://purl.obolibrary.org/obo/GO_0043165 CHEBI:83979 biolink:ChemicalSubstance D-aspartic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83979 CHEBI:83978 biolink:ChemicalSubstance L-aspartic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83978 CHEBI:83976 biolink:ChemicalSubstance 2-methyl fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83976 chebi_ph7_3 CHEBI:83972 biolink:ChemicalSubstance 3-methyl fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83972 chebi_ph7_3 GO:0102001 biolink:MolecularActivity isoleucine N-monooxygenase (oxime forming) activity Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O. RHEA:28602|MetaCyc:1.14.13.117-RXN|EC:1.14.14.39 go-plus.json http://purl.obolibrary.org/obo/GO_0102001 GO:0102003 biolink:MolecularActivity Delta8-sphingolipid desaturase activity Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor. MetaCyc:1.14.19.4-RXN|EC:1.14.19.4 go-plus.json http://purl.obolibrary.org/obo/GO_0102003 CHEBI:83989 biolink:ChemicalSubstance O-[S-(9Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83989 chebi_ph7_3 GO:0102002 biolink:MolecularActivity valine N-monooxygenase (oxime forming) activity Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O. RHEA:28606|MetaCyc:1.14.13.118-RXN|EC:1.14.14.38 go-plus.json http://purl.obolibrary.org/obo/GO_0102002 GO:0102005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102005 GO:0102004 biolink:MolecularActivity 2-octaprenyl-6-hydroxyphenol methylase activity Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine. MetaCyc:2-OCTAPRENYL-6-OHPHENOL-METHY-RXN|RHEA:27770 go-plus.json http://purl.obolibrary.org/obo/GO_0102004 GO:0102007 biolink:MolecularActivity acyl-L-homoserine-lactone lactonohydrolase activity Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine. RHEA:22576|EC:3.1.1.81|Reactome:R-HSA-8932633|MetaCyc:3.1.1.81-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102007 CHEBI:83985 biolink:ChemicalSubstance N(2)-acylglutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83985 GO:0102006 biolink:MolecularActivity 4-methyl-2-oxopentanoate dehydrogenase activity Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-). RHEA:25177|MetaCyc:2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102006 CHEBI:83983 biolink:ChemicalSubstance D-glutamic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83983 GO:0102009 biolink:MolecularActivity proline dipeptidase activity Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid. MetaCyc:3.4.13.9-RXN|EC:3.4.13.9 go-plus.json http://purl.obolibrary.org/obo/GO_0102009 CHEBI:83982 biolink:ChemicalSubstance L-glutamic acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83982 GO:0102008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102008 CHEBI:83981 biolink:ChemicalSubstance 3-hydroxyaspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83981 CHEBI:83980 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83980 GO:0018193 biolink:BiologicalProcess peptidyl-amino acid modification The alteration of an amino acid residue in a peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0018193 goslim_yeast GO:0018192 biolink:BiologicalProcess obsolete enzyme active site formation via cysteine modification to L-cysteine persulfide OBSOLETE. The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide. go-plus.json enzyme active site formation via L-cysteine persulphide http://purl.obolibrary.org/obo/GO_0018192 GO:0018195 biolink:BiologicalProcess peptidyl-arginine modification The modification of peptidyl-arginine. go-plus.json http://purl.obolibrary.org/obo/GO_0018195 GO:0018194 biolink:BiologicalProcess peptidyl-alanine modification The modification of peptidyl-alanine. go-plus.json http://purl.obolibrary.org/obo/GO_0018194 GO:0018191 biolink:BiologicalProcess peptidyl-serine octanoylation The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin. RESID:AA0290 go-plus.json http://purl.obolibrary.org/obo/GO_0018191 GO:0018190 biolink:BiologicalProcess protein octanoylation The modification of a protein amino acid by formation of an ester or amide with octanoic acid. go-plus.json protein amino acid octanoylation http://purl.obolibrary.org/obo/GO_0018190 GO:0102014 biolink:MolecularActivity beta-D-galactose-importing ATPase activity Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+. MetaCyc:ABC-18-RXN|RHEA:30011 go-plus.json http://purl.obolibrary.org/obo/GO_0102014 GO:0102013 biolink:MolecularActivity ATPase-coupled L-glutamate tranmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in). MetaCyc:ABC-13-RXN go-plus.json L-glutamate-importing ATPase activity http://purl.obolibrary.org/obo/GO_0102013 GO:0102016 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102016 GO:0102017 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102017 CHEBI:83992 biolink:ChemicalSubstance beta-D-glucosylsphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83992 chebi_ph7_3 CHEBI:83991 biolink:ChemicalSubstance imidothioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83991 GO:0018189 biolink:BiologicalProcess pyrroloquinoline quinone biosynthetic process The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed. RESID:AA0283 go-plus.json pyrroloquinoline quinone synthesis|pyrroloquinoline quinone formation|pyrroloquinoline quinone biosynthesis|PQQ biosynthesis|PQQ biosynthetic process|coenzyme pyrroloquinoline-quinone biosynthetic process|coenzyme pyrroloquinoline-quinone biosynthesis|pyrroloquinoline-quinone biosynthetic process|pyrroloquinoline-quinone biosynthesis|pyrroloquinoline quinone anabolism http://purl.obolibrary.org/obo/GO_0018189 GO:0018186 biolink:BiologicalProcess peroxidase-heme linkage The covalent linkage of heme to peroxidase. RESID:AA0280|RESID:AA0279 go-plus.json peroxidase-haem linkage http://purl.obolibrary.org/obo/GO_0018186 GO:0018185 biolink:BiologicalProcess poly-N-methyl-propylamination The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin. RESID:AA0278 go-plus.json http://purl.obolibrary.org/obo/GO_0018185 GO:0018188 biolink:BiologicalProcess peptidyl-proline di-hydroxylation The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline. RESID:AA0282 go-plus.json http://purl.obolibrary.org/obo/GO_0018188 GO:0018187 biolink:BiologicalProcess molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide. RESID:AA0281 go-plus.json http://purl.obolibrary.org/obo/GO_0018187 UBERON:0015083 biolink:AnatomicalEntity proximal tarsal bone pre-cartilage condensation A proximal tarsal endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015083 UBERON:0015082 biolink:AnatomicalEntity proximal tarsal cartilage A proximal tarsal endochondral element that is composed primarily of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015082 GO:0102023 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102023 GO:0102022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102022 GO:0102025 biolink:MolecularActivity ABC-type thiosulfate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in). RHEA:29871|EC:7.3.2.3|MetaCyc:ABC-7-RXN go-plus.json ATPase-coupled thiosulfate transmembrane transporter activity|thiosulphate ABC transporter activity|thiosulfate transmembrane-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0102025 GO:0102027 biolink:MolecularActivity S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine. RHEA:30063|EC:2.1.1.163|MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102027 GO:0102026 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102026 GO:0102029 biolink:MolecularActivity D-lactate dehydrogenase (quinone) activity Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol. MetaCyc:DLACTDEHYDROGFAD-RXN|RHEA:51468|EC:1.1.5.12 go-plus.json http://purl.obolibrary.org/obo/GO_0102029 GO:0102028 biolink:MolecularActivity cystathionine gamma-synthase activity (acts on O-phosphohomoserine) Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate. EC:2.5.1.48|MetaCyc:CYSPH-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102028 UBERON:0015081 biolink:AnatomicalEntity proximal tarsal endochondral element A proximal mesopodial endochondral element that is part of a hindlimb. go-plus.json proximal tarsal http://purl.obolibrary.org/obo/UBERON_0015081 UBERON:0015080 biolink:AnatomicalEntity proximal carpal bone pre-cartilage condensation A proximal carpal endochondral element that is composed primarily of a pre-cartilage condensation. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015080 GO:0018197 biolink:BiologicalProcess peptidyl-aspartic acid modification The modification of peptidyl-aspartic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0018197 GO:0018196 biolink:BiologicalProcess peptidyl-asparagine modification The modification of peptidyl-asparagine. go-plus.json http://purl.obolibrary.org/obo/GO_0018196 GO:0018199 biolink:BiologicalProcess peptidyl-glutamine modification The modification of peptidyl-glutamine. go-plus.json http://purl.obolibrary.org/obo/GO_0018199 GO:0018198 biolink:BiologicalProcess peptidyl-cysteine modification The modification of peptidyl-cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0018198 GO:0018171 biolink:BiologicalProcess peptidyl-cysteine oxidation The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid. RESID:AA0205|RESID:AA0262 go-plus.json http://purl.obolibrary.org/obo/GO_0018171 GO:0018170 biolink:BiologicalProcess C-terminal peptidyl-polyglutamic acid amidation The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus. RESID:AA0261 go-plus.json http://purl.obolibrary.org/obo/GO_0018170 GO:0018173 biolink:BiologicalProcess peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine. RESID:AA0265 go-plus.json peptidyl-1-thioglycine anabolism from peptidyl-glycine|peptidyl-1-thioglycine synthesis from peptidyl-glycine|peptidyl-1-thioglycine formation from peptidyl-glycine http://purl.obolibrary.org/obo/GO_0018173 GO:0018172 biolink:BiologicalProcess peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine. RESID:AA0263 go-plus.json peptidyl-L-3',4',5'-trihydroxyphenylalanine synthesis from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine anabolism from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine formation from peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0018172 GO:0018168 biolink:BiologicalProcess protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine. RESID:AA0132 go-plus.json http://purl.obolibrary.org/obo/GO_0018168 GO:0018167 biolink:BiologicalProcess protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine. RESID:AA0259 go-plus.json http://purl.obolibrary.org/obo/GO_0018167 GO:0018169 biolink:MolecularActivity ribosomal S6-glutamic acid ligase activity Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6. go-plus.json http://purl.obolibrary.org/obo/GO_0018169 GO:0018164 biolink:BiologicalProcess protein-DNA covalent cross-linking via peptidyl-threonine The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine. RESID:AA0255 go-plus.json DNA-protein covalent cross-linking via peptidyl-threonine http://purl.obolibrary.org/obo/GO_0018164 GO:0018163 biolink:BiologicalProcess protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine. RESID:AA0254 go-plus.json DNA-protein covalent cross-linking via the 5' end to peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0018163 GO:0018166 biolink:BiologicalProcess C-terminal protein-tyrosinylation The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase. RESID:AA0257 go-plus.json http://purl.obolibrary.org/obo/GO_0018166 GO:0018165 biolink:BiologicalProcess peptidyl-tyrosine uridylylation The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase. RESID:AA0256 go-plus.json http://purl.obolibrary.org/obo/GO_0018165 GO:0018182 biolink:BiologicalProcess protein-heme linkage via 3'-L-histidine The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine). RESID:AA0276 go-plus.json protein-haem linkage via 3'-L-histidine http://purl.obolibrary.org/obo/GO_0018182 GO:0018181 biolink:BiologicalProcess peptidyl-arginine C5-methylation The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine. RESID:AA0272 go-plus.json peptidyl-arginine 5-methylation http://purl.obolibrary.org/obo/GO_0018181 GO:0018184 biolink:BiologicalProcess protein polyamination The modification of a protein amino acid by polyamination. go-plus.json protein amino acid polyamination http://purl.obolibrary.org/obo/GO_0018184 GO:0018183 biolink:BiologicalProcess obsolete enzyme active site formation via S-selenyl-L-cysteine OBSOLETE. The transient selenylation of peptidyl-cysteine to form S-selenyl-L-cysteine. go-plus.json enzyme active site formation via S-selenyl-L-cysteine http://purl.obolibrary.org/obo/GO_0018183 GO:0018180 biolink:BiologicalProcess protein desulfurization The removal of a sulfur group from a protein amino acid. go-plus.json protein amino acid desulfurization|protein amino acid desulphurisation|protein amino acid desulfurisation|protein amino acid desulphurization http://purl.obolibrary.org/obo/GO_0018180 GO:0033799 biolink:MolecularActivity myricetin 3'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin. MetaCyc:RXN-8451|MetaCyc:RXN-13912|EC:2.1.1.267;|RHEA:25629|KEGG_REACTION:R06815 go-plus.json S-adenosyl-L-methionine:myricetin O-methyltransferase activity|CrCOMT2|myricetin 3-O-methyltransferase activity|flavonoid 3',5'-O-dimethyltransferase activity http://purl.obolibrary.org/obo/GO_0033799 GO:0033790 biolink:MolecularActivity hydroxymethylfurfural reductase activity Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+. go-plus.json http://purl.obolibrary.org/obo/GO_0033790 GO:0033798 biolink:MolecularActivity thyroxine 5-deiodinase activity Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2. RHEA:18897|EC:1.21.99.3|MetaCyc:1.97.1.11-RXN go-plus.json diiodothyronine 5'-deiodinase activity|acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity|iodothyronine inner ring monodeiodinase activity|type III iodothyronine deiodinase activity|inner ring-deiodinating pathway|iodothyronine 5-deiodinase activity http://purl.obolibrary.org/obo/GO_0033798 GO:0018179 biolink:BiologicalProcess obsolete peptidyl-cysteine desulfurization OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate. RESID:AA0269 go-plus.json peptidyl-cysteine desulphurization|peptidyl-cysteine desulfurization http://purl.obolibrary.org/obo/GO_0018179 GO:0033797 biolink:MolecularActivity selenate reductase activity Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite. KEGG_REACTION:R07229|RHEA:14029|EC:1.97.1.9|UM-BBD_reactionID:r0828|MetaCyc:RXN0-2101 go-plus.json selenite:reduced acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033797 GO:0018178 biolink:BiologicalProcess peptidyl-threonine adenylylation The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine. RESID:AA0267 go-plus.json peptidyl-threonine adenylation http://purl.obolibrary.org/obo/GO_0018178 GO:0033796 biolink:MolecularActivity sulfur reductase activity Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide. RHEA:35591|EC:1.12.98.4|MetaCyc:RXN-8269|MetaCyc:1.97.1.3-RXN go-plus.json (donor):sulfur oxidoreductase activity|sulphur reductase activity http://purl.obolibrary.org/obo/GO_0033796 GO:0033795 biolink:MolecularActivity betaine reductase activity Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin. EC:1.21.4.4|RHEA:11848 go-plus.json acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity http://purl.obolibrary.org/obo/GO_0033795 GO:0018175 biolink:BiologicalProcess protein nucleotidylation The addition of a nucleotide to a protein amino acid. go-plus.json protein amino acid nucleotidylation http://purl.obolibrary.org/obo/GO_0018175 GO:0033794 biolink:MolecularActivity sarcosine reductase activity Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin. EC:1.21.4.3|RHEA:12825 go-plus.json acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity http://purl.obolibrary.org/obo/GO_0033794 GO:0018174 biolink:BiologicalProcess protein-heme P460 linkage The linkage of protein to heme P460. RESID:AA0266|RESID:AA0271 go-plus.json protein-haem P460 linkage http://purl.obolibrary.org/obo/GO_0018174 GO:0033793 biolink:MolecularActivity aureusidin synthase activity Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O. go-plus.json 2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033793 GO:0018177 biolink:BiologicalProcess protein uridylylation The addition of phospho-uridine to a protein amino acid. go-plus.json protein amino acid uridylylation http://purl.obolibrary.org/obo/GO_0018177 GO:0033792 biolink:MolecularActivity bile-acid 7alpha-dehydroxylase activity Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2. MetaCyc:RXN-8659|MetaCyc:RXN-8658|EC:1.17.99.5 go-plus.json bile acid 7-dehydroxylase activity|deoxycholate:NAD+ oxidoreductase activity|cholate 7alpha-dehydroxylase activity|deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity|7alpha-dehydroxylase activity http://purl.obolibrary.org/obo/GO_0033792 GO:0033791 biolink:MolecularActivity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor. RHEA:15733|MetaCyc:1.17.99.3-RXN|EC:1.17.99.3 go-plus.json 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity|THC-CoA oxidase activity|THCA-CoA oxidase activity|(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity|trihydroxycoprostanoyl-CoA oxidase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity http://purl.obolibrary.org/obo/GO_0033791 GO:0018176 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018176 GO:0018151 biolink:BiologicalProcess peptide cross-linking via L-histidyl-L-tyrosine The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link. go-plus.json http://purl.obolibrary.org/obo/GO_0018151 GO:0018150 biolink:BiologicalProcess peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link. RESID:AA0250 go-plus.json http://purl.obolibrary.org/obo/GO_0018150 GO:0033789 biolink:MolecularActivity phenylacetyl-CoA dehydrogenase activity Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA. MetaCyc:1.17.5.1-RXN|RHEA:15705|EC:1.17.5.1|KEGG_REACTION:R07222 go-plus.json phenylacetyl-CoA:quinone oxidoreductase activity|phenylacetyl-CoA:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033789 GO:0033788 biolink:MolecularActivity leucoanthocyanidin reductase activity Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+. MetaCyc:RXN-1484|RHEA:10616|EC:1.17.1.3 go-plus.json (2R,3S)-catechin:NADP+ 4-oxidoreductase activity|leucocyanidin reductase activity http://purl.obolibrary.org/obo/GO_0033788 GO:0018149 biolink:BiologicalProcess peptide cross-linking The formation of a covalent cross-link between or within protein chains. go-plus.json http://purl.obolibrary.org/obo/GO_0018149 GO:0018146 biolink:BiologicalProcess keratan sulfate biosynthetic process The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. RESID:AA0247 go-plus.json keratan sulfate anabolism|keratan sulfate synthesis|keratan sulfate formation|keratan sulfate biosynthesis|keratan sulphate biosynthetic process|keratan sulphate biosynthesis http://purl.obolibrary.org/obo/GO_0018146 GO:0033787 biolink:MolecularActivity cyanocobalamin reductase (cyanide-eliminating) activity Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH. Reactome:R-HSA-3149519|KEGG_REACTION:R02999|EC:1.16.1.6|RHEA:16113|MetaCyc:1.6.99.12-RXN go-plus.json cob(I)alamin, cyanide:NADP+ oxidoreductase activity|cyanocobalamin reductase (NADPH, cyanide-eliminating) activity|NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|cyanocobalamin reductase activity|cyanocobalamin reductase (NADPH; CN-eliminating) activity http://purl.obolibrary.org/obo/GO_0033787 GO:0033786 biolink:MolecularActivity heptose-1-phosphate adenylyltransferase activity Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose. MetaCyc:RXN0-4342|RHEA:27465 go-plus.json D-beta-D-heptose 1-phosphate adenylyltransferase activity|heptose 1-phosphate adenyltransferase activity http://purl.obolibrary.org/obo/GO_0033786 GO:0018145 biolink:BiologicalProcess protein-DNA covalent cross-linking via peptidyl-serine The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine. RESID:AA0246 go-plus.json DNA-protein covalent cross-linking via peptidyl-serine http://purl.obolibrary.org/obo/GO_0018145 GO:0018148 biolink:BiologicalProcess RNA-protein covalent cross-linking via peptidyl-tyrosine The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine. RESID:AA0249 go-plus.json http://purl.obolibrary.org/obo/GO_0018148 CHEBI:138483 biolink:ChemicalSubstance cis-3,4-dialkyloxetan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138483 chebi_ph7_3 GO:0033785 biolink:MolecularActivity heptose 7-phosphate kinase activity Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP. MetaCyc:RXN0-4341|EC:2.7.1.167|RHEA:27473 go-plus.json D-alpha,beta-D-heptose 7-phosphate 1-kinase activity http://purl.obolibrary.org/obo/GO_0033785 GO:0033784 biolink:MolecularActivity senecionine N-oxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide. MetaCyc:1.14.13.101-RXN|EC:1.14.13.101|RHEA:11420|KEGG_REACTION:R07373 go-plus.json senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity|SNO|senecionine monooxygenase (N-oxide-forming) activity http://purl.obolibrary.org/obo/GO_0033784 CHEBI:138482 biolink:ChemicalSubstance N(2)-[(3R)-hydroxy-acyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138482 chebi_ph7_3 GO:0018147 biolink:BiologicalProcess molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide). RESID:AA0248 go-plus.json http://purl.obolibrary.org/obo/GO_0018147 GO:0033783 biolink:MolecularActivity 25-hydroxycholesterol 7alpha-hydroxylase activity Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O. RHEA:19041|MetaCyc:RXN-7981|MetaCyc:RXN-7980|EC:1.14.14.29 go-plus.json CYP7B1|25-hydroxycholesterol 7alpha-monooxygenase activity|CYP7B1 oxysterol 7alpha-hydroxylase activity|cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0033783 GO:0018142 biolink:BiologicalProcess protein-DNA covalent cross-linking The formation of a covalent cross-link between DNA and a protein. go-plus.json DNA-protein covalent cross-linking http://purl.obolibrary.org/obo/GO_0018142 GO:0033782 biolink:MolecularActivity 24-hydroxycholesterol 7alpha-hydroxylase activity Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. EC:1.14.14.26|KEGG_REACTION:R07208|MetaCyc:1.14.13.99-RXN|RHEA:46124 go-plus.json 24-hydroxycholesterol 7alpha-monooxygenase activity|24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0033782 GO:0018141 biolink:BiologicalProcess peptide cross-linking via L-lysine thiazolecarboxylic acid The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. RESID:AA0245 go-plus.json http://purl.obolibrary.org/obo/GO_0018141 GO:0033781 biolink:MolecularActivity cholesterol 24-hydroxylase activity Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+). EC:1.14.14.25|RHEA:22716|KEGG_REACTION:R07207|MetaCyc:1.14.13.98-RXN|Reactome:R-HSA-192061 go-plus.json CYP46A1|cholesterol 24S-hydroxylase activity|cytochrome P450 46A1|CYP46|cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity|cholesterol 24-monooxygenase activity http://purl.obolibrary.org/obo/GO_0033781 GO:0018144 biolink:BiologicalProcess RNA-protein covalent cross-linking The formation of a covalent cross-link between RNA and a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018144 GO:0033780 biolink:MolecularActivity taurochenodeoxycholate 6alpha-hydroxylase activity Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O. MetaCyc:RXN-7977|EC:1.14.13.97|RHEA:23644 go-plus.json CYP4A21|taurochenodeoxycholate 6alpha-monooxygenase activity|taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity|CYP3A4 http://purl.obolibrary.org/obo/GO_0033780 GO:0018143 biolink:BiologicalProcess nucleic acid-protein covalent cross-linking The formation of a covalent cross-link between a nucleic acid and a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018143 GO:0018160 biolink:BiologicalProcess peptidyl-pyrromethane cofactor linkage The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine. RESID:AA0252 go-plus.json peptidyl-pyrromethane cofactor linkage via dipyrrolylmethanemethyl-L-cysteine|dipyrromethane cofactor binding http://purl.obolibrary.org/obo/GO_0018160 GO:0018162 biolink:BiologicalProcess peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine. RESID:AA0253 go-plus.json http://purl.obolibrary.org/obo/GO_0018162 GO:0018161 biolink:BiologicalProcess dipyrrin biosynthetic process The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group. go-plus.json dipyrromethane biosynthesis|dipyrromethane biosynthetic process|dipyrrin biosynthesis|dipyrrin anabolism|dipyrrin synthesis|dipyrrin formation http://purl.obolibrary.org/obo/GO_0018161 GO:0033779 biolink:MolecularActivity 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+). KEGG_REACTION:R07204|MetaCyc:1.14.13.96-RXN|RHEA:15261|EC:1.14.14.139 go-plus.json cytochrome P450 8B1|5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity|sterol 12alpha-hydroxylase activity|5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|CYP8B1 http://purl.obolibrary.org/obo/GO_0033779 GO:0033778 biolink:MolecularActivity 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+). KEGG_REACTION:R04826|RHEA:10504|MetaCyc:1.14.13.95-RXN|Reactome:R-HSA-192157|Reactome:R-HSA-193845|Reactome:R-HSA-193709|EC:1.14.14.139 go-plus.json CYP12|7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|sterol 12alpha-hydroxylase activity|HCO 12alpha-hydroxylase activity|7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity http://purl.obolibrary.org/obo/GO_0033778 GO:0033777 biolink:MolecularActivity lithocholate 6beta-hydroxylase activity Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+). RHEA:18857|KEGG_REACTION:R07203|MetaCyc:1.14.13.94-RXN|EC:1.14.14.138 go-plus.json lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity|6beta-hydroxylase activity|lithocholate 6beta-monooxygenase activity|CYP3A10|cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0033777 GO:0033776 biolink:MolecularActivity phenylacetone monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+). RHEA:10124|KEGG_REACTION:R07201|MetaCyc:1.14.13.92-RXN|EC:1.14.13.92 go-plus.json phenylacetone,NADPH:oxygen oxidoreductase activity|PAMO http://purl.obolibrary.org/obo/GO_0033776 GO:0018157 biolink:BiologicalProcess peptide cross-linking via an oxazole or thiazole The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. go-plus.json peptide heterocycle formation|peptide heterocycle biosynthesis|peptide heterocycle synthesis|peptide heterocycle biosynthetic process http://purl.obolibrary.org/obo/GO_0018157 GO:0033775 biolink:MolecularActivity deoxysarpagine hydroxylase activity Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine. RHEA:14237|MetaCyc:1.14.13.91-RXN|EC:1.14.14.136|KEGG_REACTION:R05828 go-plus.json DOSH|10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0033775 GO:0018156 biolink:BiologicalProcess peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine). RESID:AA0112 go-plus.json http://purl.obolibrary.org/obo/GO_0018156 GO:0018159 biolink:BiologicalProcess peptidyl-methionine oxidation The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone. RESID:AA0251 go-plus.json http://purl.obolibrary.org/obo/GO_0018159 GO:0033774 biolink:CellularComponent basal labyrinth A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0033774 GO:0033773 biolink:MolecularActivity isoflavone 2'-hydroxylase activity Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. EC:1.14.14.90|RHEA:18849|MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN go-plus.json CYP Ge-3|CYP81E1|isoflavone 2'-monooxygenase activity http://purl.obolibrary.org/obo/GO_0033773 GO:0018158 biolink:BiologicalProcess protein oxidation The modification of a protein amino acid by oxidation. go-plus.json protein amino acid oxidation http://purl.obolibrary.org/obo/GO_0018158 GO:0033772 biolink:MolecularActivity flavonoid 3',5'-hydroxylase activity Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O. RHEA:55448|MetaCyc:RXN-8671|MetaCyc:RXN-7783|EC:1.14.14.81 go-plus.json F3',5'H|F3'5'H|flavanone,NADPH:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0033772 GO:0018153 biolink:BiologicalProcess isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine. RESID:AA0124 go-plus.json http://purl.obolibrary.org/obo/GO_0018153 GO:0033771 biolink:MolecularActivity licodione synthase activity Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+). MetaCyc:1.14.13.87-RXN|RHEA:15697|KEGG_REACTION:R07198|EC:1.14.14.140 go-plus.json liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity|(2S)-flavanone 2-hydroxylase activity http://purl.obolibrary.org/obo/GO_0033771 GO:0018152 biolink:BiologicalProcess peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link. RESID:AA0270 go-plus.json http://purl.obolibrary.org/obo/GO_0018152 GO:0018155 biolink:BiologicalProcess peptide cross-linking via sn-(2S,6R)-lanthionine The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione). RESID:AA0111 go-plus.json http://purl.obolibrary.org/obo/GO_0018155 GO:0033770 biolink:MolecularActivity 2-hydroxyisoflavanone synthase activity Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O. RHEA:14897|EC:1.14.13.86|MetaCyc:RXN-7750 go-plus.json 2-HIS|apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity http://purl.obolibrary.org/obo/GO_0033770 GO:0018154 biolink:BiologicalProcess peptide cross-linking via (2R,6R)-lanthionine The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine). RESID:AA0110 go-plus.json http://purl.obolibrary.org/obo/GO_0018154 UBERON:0015153 biolink:AnatomicalEntity medial gland of ocular region A gland that is located in the ocular region, nearer the inner canthi. Typically associated with or part of the nictitating membrane, when present go-plus.json Harderian gland|medial orbital gland|medial ocular gland http://purl.obolibrary.org/obo/UBERON_0015153 GO:0102072 biolink:MolecularActivity obsolete 3-oxo-cis-Delta9-hexadecenoyl-[acp] reductase activity OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxy cis Delta9-hexadecenoyl-[acp] <=> NADPH + H+ + a 3-oxo-cis-Delta9-hexadecenoyl-[acp]. go-plus.json http://purl.obolibrary.org/obo/GO_0102072 GO:0102071 biolink:MolecularActivity 9,10-epoxy-18-hydroxystearate hydrolase activity Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate. MetaCyc:RXN-1065 go-plus.json http://purl.obolibrary.org/obo/GO_0102071 UBERON:0015152 biolink:AnatomicalEntity gland of ocular region A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. go-plus.json ocular gland|orbital gland http://purl.obolibrary.org/obo/UBERON_0015152 PO:0005656 biolink:OntologyClass portion of secretory tissue A portion of plant tissue (PO:0009007) that form specialized structures producing a secretion. go-plus.json 分泌組織の一部 (Japanese, exact)|porción del tejido secretor (Spanish, exact)|gland (related) http://purl.obolibrary.org/obo/PO_0005656 UBERON:0015155 biolink:AnatomicalEntity conjunctival space A anatomical space that is enclosed by a conjunctiva. go-plus.json conjunctival sac cavity|subbrillar space|subconjunctival space|cavity of conjunctival sac http://purl.obolibrary.org/obo/UBERON_0015155 GO:0102074 biolink:MolecularActivity OPC6-trans-2-enoyl-CoA hydratase activity Catalysis of the reaction: OPC6-3-hydroxyacyl-CoA <=> OPC6-trans-2-enoyl-CoA + H2O. MetaCyc:RXN-10704 go-plus.json http://purl.obolibrary.org/obo/GO_0102074 CHEBI:58939 biolink:ChemicalSubstance 2-(1-hydroxyethyl)thiamine diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58939 chebi_ph7_3 UBERON:0015154 biolink:AnatomicalEntity lateral gland of orbital region A gland that is located in or around the ocular region, nearer the outer canthi. go-plus.json lateral ocular gland|lateral orbital gland http://purl.obolibrary.org/obo/UBERON_0015154 GO:0102073 biolink:MolecularActivity OPC8-trans-2-enoyl-CoA hydratase activity Catalysis of the reaction: OPC8-3-hydroxyacyl-CoA <=> OPC8-trans-2-enoyl-CoA + H2O. MetaCyc:RXN-10697 go-plus.json http://purl.obolibrary.org/obo/GO_0102073 CHEBI:58938 biolink:ChemicalSubstance thiamine(1+) triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58938 chebi_ph7_3 GO:0102076 biolink:MolecularActivity beta,beta-carotene-9',10'-cleaving oxygenase activity Catalysis of the reaction: beta-carotene + O2 <=> 10'-apo-beta-carotenal + beta-ionone. EC:1.13.11.71|RHEA:26389|MetaCyc:RXN-10741 go-plus.json http://purl.obolibrary.org/obo/GO_0102076 CHEBI:58937 biolink:ChemicalSubstance thiamine(1+) diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58937 chebi_ph7_3 GO:0102075 biolink:MolecularActivity OPC4-trans-2-enoyl-CoA hydratase activity Catalysis of the reaction: OPC4-3-hydroxyacyl-CoA <=> OPC4-trans-2-enoyl-CoA + H2O. MetaCyc:RXN-10705 go-plus.json http://purl.obolibrary.org/obo/GO_0102075 CHEBI:58936 biolink:ChemicalSubstance 2,4-dihydroxyhept-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58936 chebi_ph7_3 UBERON:0015151 biolink:AnatomicalEntity Harderian gland duct A duct that is part of a Harderian gland. opens into the conjunctival sac at the base of the nictitating membrane. go-plus.json duct of Harderian gland|duct of Harder's gland|Harderian duct http://purl.obolibrary.org/obo/UBERON_0015151 GO:0102078 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102078 CHEBI:58935 biolink:ChemicalSubstance 2,4-diazaniumylpentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58935 chebi_ph7_3 UBERON:0015150 biolink:AnatomicalEntity dorsal hair A strand of hair that is part of a dorsum. go-plus.json back hair|dorsal coat hair|hair of back http://purl.obolibrary.org/obo/UBERON_0015150 GO:0102077 biolink:MolecularActivity oleamide hydrolase activity Catalysis of the reaction: oleamide + H2O <=> oleate + ammonium. RHEA:26506|EC:3.5.1.99|MetaCyc:RXN-10756 go-plus.json http://purl.obolibrary.org/obo/GO_0102077 CHEBI:19327 biolink:ChemicalSubstance 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19327 chebi_ph7_3 CHEBI:58934 biolink:ChemicalSubstance 2,2'-iminodipropanoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58934 chebi_ph7_3 CHEBI:58933 biolink:ChemicalSubstance propanoyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58933 chebi_ph7_3 CHEBI:19324 biolink:ChemicalSubstance 2,3-bisphosphoglycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19324 chebi_ph7_3 CHEBI:58931 biolink:ChemicalSubstance oxalatosuccinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58931 chebi_ph7_3 CHEBI:58930 biolink:ChemicalSubstance 16-methoxytabersoninium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58930 chebi_ph7_3 GO:0102081 biolink:MolecularActivity homotaurine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-). MetaCyc:RXN-10822 go-plus.json http://purl.obolibrary.org/obo/GO_0102081 GO:0102080 biolink:MolecularActivity phenylacetyl-coenzyme A:glycine N-acyltransferase activity Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A. RHEA:27850|MetaCyc:RXN-10821|EC:2.3.1.192 go-plus.json http://purl.obolibrary.org/obo/GO_0102080 GO:0102083 biolink:MolecularActivity 7,8-dihydromonapterin aldolase activity Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol. MetaCyc:RXN-10857 go-plus.json http://purl.obolibrary.org/obo/GO_0102083 UBERON:0015142 biolink:AnatomicalEntity falciform fat A large fat pad that is located at the base of the abdominal wall, in the falciform ligament of the liver. go-plus.json falciform fat depot|falciform ligament fat pad http://purl.obolibrary.org/obo/UBERON_0015142 GO:0102082 biolink:MolecularActivity demethylrebeccamycin--D-glucose O-methyltransferase activity Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine. MetaCyc:RXN-10847|RHEA:27353|EC:2.1.1.164 go-plus.json http://purl.obolibrary.org/obo/GO_0102082 PO:0005645 biolink:OntologyClass leaf mesophyll The chloroplast-containing, photosynthetic parenchymatous tissue situated between the two epidermal layers of the foliage leaf. go-plus.json 葉の葉肉 (Japanese, exact) (exact)|foliage leaf mesophyll (related)|leaf parenchyma (related)|mesófilo de la hoja (Spanish, exact) http://purl.obolibrary.org/obo/PO_0005645 UBERON:0015144 biolink:AnatomicalEntity autopod hair A strand of hair that is part of a autopod region. go-plus.json hair of hand/foot|paw hair|hand/foot hair http://purl.obolibrary.org/obo/UBERON_0015144 CHEBI:58929 biolink:ChemicalSubstance N(4)-acetyl-L-2,4-diaminobutyric acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58929 chebi_ph7_3 GO:0102085 biolink:MolecularActivity N-(4-aminobenzoyl)-L-glutamate synthetase activity Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid. MetaCyc:RXN-10884 go-plus.json http://purl.obolibrary.org/obo/GO_0102085 GO:0102084 biolink:MolecularActivity L-dopa O-methyltransferase activity Catalysis of the reaction: L-dopa + S-adenosyl-L-methionine <=> 3-O-methyldopa + S-adenosyl-L-homocysteine + H+. EC:2.1.1.6|MetaCyc:RXN-10870 go-plus.json http://purl.obolibrary.org/obo/GO_0102084 UBERON:0015143 biolink:AnatomicalEntity mesenteric fat pad Encapsulated adipose tissue associated with the mesentery go-plus.json mesenteric fat depot http://purl.obolibrary.org/obo/UBERON_0015143 CHEBI:58928 biolink:ChemicalSubstance N-formimidoyl-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58928 chebi_ph7_3 CHEBI:83905 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83905 chebi_ph7_3 GO:0102087 biolink:MolecularActivity N-benzoyl-L-glutamate synthetase activity Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid. MetaCyc:RXN-10886 go-plus.json http://purl.obolibrary.org/obo/GO_0102087 CHEBI:58927 biolink:ChemicalSubstance L-lupinic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58927 chebi_ph7_3 GO:0102086 biolink:MolecularActivity N-vanillate-L-glutamate synthetase activity Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid. MetaCyc:RXN-10885 go-plus.json http://purl.obolibrary.org/obo/GO_0102086 CHEBI:83903 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-L-lysinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83903 chebi_ph7_3 PO:0005648 biolink:OntologyClass palisade mesophyll Parenchyma containing closely packed elongated chlorenchymatous cells oriented perpendicular to the leaf surface and which are active in photosynthesis. go-plus.json 柵状葉肉 (Japanese, exact)|palisade parenchyma (related)|mesófilo en empalizada (Spanish, exact) http://purl.obolibrary.org/obo/PO_0005648 GO:0102089 biolink:MolecularActivity dehydroscoulerine synthase activity Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+. MetaCyc:RXN-10888 go-plus.json http://purl.obolibrary.org/obo/GO_0102089 CHEBI:58925 biolink:ChemicalSubstance kaempferide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58925 chebi_ph7_3 GO:0102088 biolink:MolecularActivity N-(4-hydroxybenzoyl)-L-glutamate synthetase activity Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP <=> H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid. MetaCyc:RXN-10887 go-plus.json http://purl.obolibrary.org/obo/GO_0102088 CHEBI:58924 biolink:ChemicalSubstance isopimarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58924 chebi_ph7_3 UBERON:0015149 biolink:AnatomicalEntity ventral hair A strand of hair that is part of a ventrum. go-plus.json ventral coat hair http://purl.obolibrary.org/obo/UBERON_0015149 CHEBI:83900 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83900 chebi_ph7_3 CHEBI:10986 biolink:ChemicalSubstance (R)-4'-phosphonatopantothenate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_10986 chebi_ph7_3 UBERON:0015146 biolink:AnatomicalEntity manus hair A strand of hair that is part of a manus. go-plus.json hair of hand|front paw hair|hand hair http://purl.obolibrary.org/obo/UBERON_0015146 UBERON:0015145 biolink:AnatomicalEntity pes hair A strand of hair that is part of a pes. go-plus.json hind foot hair|hind paw hair|hair of foot|foot hair http://purl.obolibrary.org/obo/UBERON_0015145 UBERON:0015148 biolink:AnatomicalEntity tail hair A strand of hair that is part of a tail. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015148 UBERON:0015147 biolink:AnatomicalEntity pinna hair A strand of hair that is part of a pinna. go-plus.json ear hair http://purl.obolibrary.org/obo/UBERON_0015147 CHEBI:10980 biolink:ChemicalSubstance (R)-3-(4-hydroxyphenyl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_10980 chebi_ph7_3 CHEBI:10983 biolink:ChemicalSubstance (R)-3-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_10983 chebi_ph7_3 CHEBI:58923 biolink:ChemicalSubstance lipoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58923 chebi_ph7_3 CHEBI:58922 biolink:ChemicalSubstance Ile(5)-angiotensin II (1-7) dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58922 chebi_ph7_3 CHEBI:58921 biolink:ChemicalSubstance N-acyl-L-homoserinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58921 chebi_ph7_3 CHEBI:58920 biolink:ChemicalSubstance (S)-piperazine-2-carboxylic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58920 chebi_ph7_3 GO:0102090 biolink:MolecularActivity adrenaline O-methyltransferase activity Catalysis of the reaction: (R)-adrenaline(1+) + S-adenosyl-L-methionine <=> metanephrine + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-10909 go-plus.json http://purl.obolibrary.org/obo/GO_0102090 GO:0102092 biolink:MolecularActivity 5-diphosphoinositol pentakisphosphate 3-kinase activity Catalysis of the reaction: 5-diphospho-1D-myo-inositol pentakisphosphate + ATP = 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP. EC:2.7.4.24|MetaCyc:RXN-10979 go-plus.json http://purl.obolibrary.org/obo/GO_0102092 GO:0102091 biolink:MolecularActivity phosphatidylinositol-5-phosphate 5-phosphatase activity Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = hydrogenphosphate + an L-1-phosphatidyl-inositol. MetaCyc:RXN-10962 go-plus.json http://purl.obolibrary.org/obo/GO_0102091 GO:0102094 biolink:MolecularActivity S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a demethylmenaquinol <=> S-adenosyl-L-homocysteine + H+ + a menaquinol. RHEA:26466|EC:2.1.1.163|MetaCyc:RXN-11046 go-plus.json http://purl.obolibrary.org/obo/GO_0102094 CHEBI:19351 biolink:ChemicalSubstance (2,4-dichlorophenoxy)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19351 chebi_ph7_3 CHEBI:58919 biolink:ChemicalSubstance (S)-piperazin-4-ium-2-carboxamide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58919 chebi_ph7_3 UBERON:0015130 biolink:AnatomicalEntity connective tissue of prostate gland A portion of connective tissue that is part of a prostate gland. go-plus.json connective tissue of prostate http://purl.obolibrary.org/obo/UBERON_0015130 GO:0102093 biolink:MolecularActivity acrylate:acyl-coA CoA transferase activity Catalysis of the reaction: acryloyl-CoA + H2O <=> acrylate + coenzyme A + H+. MetaCyc:RXN-10985 go-plus.json http://purl.obolibrary.org/obo/GO_0102093 GO:0102096 biolink:MolecularActivity decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+. MetaCyc:RXN-11070|RHEA:34487|EC:2.4.1.289 go-plus.json http://purl.obolibrary.org/obo/GO_0102096 CHEBI:58918 biolink:ChemicalSubstance beta-alaninium amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_58918 chebi_ph7_3 CHEBI:58917 biolink:ChemicalSubstance (R)-piperazine-2-carboxylic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58917 chebi_ph7_3 GO:0102098 biolink:MolecularActivity D-galacturonate reductase activity Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+. MetaCyc:RXN-11151|RHEA:26345|EC:1.1.1.365 go-plus.json http://purl.obolibrary.org/obo/GO_0102098 CHEBI:58916 biolink:ChemicalSubstance (R)-piperazin-4-ium-2-carboxamide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58916 chebi_ph7_3 CHEBI:83916 biolink:ChemicalSubstance omega-hydroxyphytanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83916 chebi_ph7_3 CHEBI:58915 biolink:ChemicalSubstance (2E)-but-2-ene-1,2,3-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58915 chebi_ph7_3 GO:0102097 biolink:MolecularActivity (22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O. RHEA:27325|EC:1.14.14.147|MetaCyc:RXN-11101 go-plus.json http://purl.obolibrary.org/obo/GO_0102097 NCBITaxon:1113537 biolink:OrganismalEntity Chlamydia/Chlamydophila group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1113537 CHEBI:58914 biolink:ChemicalSubstance all-trans-polyprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58914 chebi_ph7_3 CHEBI:83914 biolink:ChemicalSubstance omega-hydroxy-15-methylpalmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83914 chebi_ph7_3 GO:0102099 biolink:MolecularActivity FAD-dependent urate hydroxylase activity Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O. MetaCyc:RXN-11186|RHEA:27329|EC:1.14.13.113 go-plus.json http://purl.obolibrary.org/obo/GO_0102099 CHEBI:58913 biolink:ChemicalSubstance delphinidin-5-olate 3-O-(6''-O-carboxylatoacetyl)-beta-D-glucoside-3'-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58913 chebi_ph7_3 CHEBI:83912 biolink:ChemicalSubstance N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl)-D-lysine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83912 chebi_ph7_3 CHEBI:58912 biolink:ChemicalSubstance ternatin C5(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58912 chebi_ph7_3 CHEBI:58911 biolink:ChemicalSubstance delphinidin-5-olate 3-O-(6''-O-carboxylatoacetyl)-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58911 CHEBI:58910 biolink:ChemicalSubstance thyroxine sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58910 chebi_ph7_3 CHEBI:58909 biolink:ChemicalSubstance 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58909 chebi_ph7_3 CHEBI:58908 biolink:ChemicalSubstance L-galactose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58908 chebi_ph7_3 CHEBI:58907 biolink:ChemicalSubstance precursor Z(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58907 CHEBI:58906 biolink:ChemicalSubstance sphingosine-1-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58906 chebi_ph7_3 CHEBI:58905 biolink:ChemicalSubstance S-sulfanylglutathionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58905 chebi_ph7_3 UBERON:1100000 biolink:AnatomicalEntity digestive tract junction An anatomical junction between two parts of the digestive tract. go-plus.json http://purl.obolibrary.org/obo/UBERON_1100000 CHEBI:83925 biolink:ChemicalSubstance non-proteinogenic alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83925 CHEBI:58903 biolink:ChemicalSubstance Delta(11)-fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58903 chebi_ph7_3 CHEBI:58902 biolink:ChemicalSubstance beta-L-aspartylhydroxamic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58902 chebi_ph7_3 UBERON:0015128 biolink:AnatomicalEntity subepicardial layer of epicardium go-plus.json subepicardial connective tissue|perimysial connective tissue of subepicardium http://purl.obolibrary.org/obo/UBERON_0015128 CHEBI:83922 biolink:ChemicalSubstance (R)-fenbuconazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_83922 chebi_ph7_3 CHEBI:83921 biolink:ChemicalSubstance (S)-fenbuconazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_83921 chebi_ph7_3 UBERON:0015129 biolink:AnatomicalEntity epicardial fat Visceral intrapericardial fat contiguous with the myocardial surface. go-plus.json epicardial adipose tissue|pericardial adipose tissue http://purl.obolibrary.org/obo/UBERON_0015129 CHEBI:83920 biolink:ChemicalSubstance 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_83920 chebi_ph7_3 CHEBI:58901 biolink:ChemicalSubstance 2-(E)-O-feruloyl-D-galactarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58901 chebi_ph7_3 CHEBI:58900 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-D-glucuronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58900 chebi_ph7_3 CHEBI:19333 biolink:ChemicalSubstance 2,4,6-trichloroanisole go-plus.json http://purl.obolibrary.org/obo/CHEBI_19333 chebi_ph7_3 CHEBI:19331 biolink:ChemicalSubstance (2,4,5-trichlorophenoxy)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19331 chebi_ph7_3 GO:0102030 biolink:MolecularActivity dTDP-L-rhamnose synthetase activity Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+. MetaCyc:DTDPRHAMSYNTHMULTI-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102030 CHEBI:83939 biolink:ChemicalSubstance 1-acyl-2-stearoyl-sn-glycero-3-phospho-(1D-myo-inositol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83939 chebi_ph7_3 CHEBI:83938 biolink:ChemicalSubstance 14-hydroxypalmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83938 chebi_ph7_3 CHEBI:83937 biolink:ChemicalSubstance 14-hydroxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83937 GO:0102031 biolink:MolecularActivity 4-acetamido-4,6-dideoxy-D-galactose transferase activity Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP. RHEA:28759|EC:2.4.1.325|MetaCyc:FUC4NACTRANS-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102031 CHEBI:83936 biolink:ChemicalSubstance 15-hydroxypalmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83936 chebi_ph7_3 CHEBI:83935 biolink:ChemicalSubstance 15-hydroxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83935 GO:0102033 biolink:MolecularActivity long-chain fatty acid omega-hydroxylase activity Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:56748|MetaCyc:RXN-16394|EC:1.14.14.80 go-plus.json cytochrome P450 fatty acid omega-hydroxylase activity http://purl.obolibrary.org/obo/GO_0102033 GO:0102036 biolink:MolecularActivity methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein]. MetaCyc:METHCOCLTH-RXN|RHEA:45200|EC:2.1.1.258 go-plus.json http://purl.obolibrary.org/obo/GO_0102036 CHEBI:10956 biolink:ChemicalSubstance (E)-cinnamoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_10956 GO:0102035 biolink:MolecularActivity isobutyryl-CoA:FAD oxidoreductase activity Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2. MetaCyc:MEPROPCOA-FAD-RXN|EC:1.3.8.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102035 GO:0102038 biolink:MolecularActivity 4-nitrobenzyl alcohol oxidase activity Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide. MetaCyc:R362-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102038 GO:0102037 biolink:MolecularActivity 4-nitrotoluene monooxygenase activity Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O. MetaCyc:R361-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102037 GO:0102039 biolink:MolecularActivity alkylhydroperoxide reductase activity Catalysis of the reaction: H2O + NAD + an alcohol <=> NADH + H+ + an organic hydroperoxide. EC:1.11.1.26|MetaCyc:R4-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102039 GO:0102041 biolink:MolecularActivity 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid. RHEA:35951|EC:2.5.1.105|MetaCyc:RXN-10009 go-plus.json http://purl.obolibrary.org/obo/GO_0102041 GO:0102040 biolink:MolecularActivity fumarate reductase (menaquinone) Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone. RHEA:27834|EC:1.3.5.4|MetaCyc:R601-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0102040 GO:0102043 biolink:MolecularActivity isopentenyl phosphate kinase activity Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-). RHEA:33963|EC:2.7.4.26|MetaCyc:RXN-10068 go-plus.json http://purl.obolibrary.org/obo/GO_0102043 GO:0102042 biolink:MolecularActivity dehydroquinate synthase activity Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+. MetaCyc:RXN-10032|EC:1.4.1.24|RHEA:25956 go-plus.json http://purl.obolibrary.org/obo/GO_0102042 UBERON:0015181 biolink:AnatomicalEntity neck of tooth The slightly constricted part of a tooth, between the crown and the root. go-plus.json cervix dentis|cervical zone of tooth|cervical margin of tooth|tooth neck|dental neck|cervix of tooth|collumn dentis http://purl.obolibrary.org/obo/UBERON_0015181 GO:0102045 biolink:MolecularActivity 3-chlorobenzoate-3,4-oxygenase activity Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor. MetaCyc:RXN-10422 go-plus.json http://purl.obolibrary.org/obo/GO_0102045 GO:0102044 biolink:MolecularActivity 3-chlorobenzoate-4,5-oxygenase activity Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor. MetaCyc:RXN-10421 go-plus.json http://purl.obolibrary.org/obo/GO_0102044 CHEBI:83946 biolink:ChemicalSubstance N-acyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83946 GO:0102047 biolink:MolecularActivity indole-3-acetyl-glycine synthetase activity Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10429 go-plus.json http://purl.obolibrary.org/obo/GO_0102047 CHEBI:83944 biolink:ChemicalSubstance D-alanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83944 GO:0102046 biolink:MolecularActivity 3,4-dichlorobenzoate-4,5-oxygenase activity Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor. MetaCyc:RXN-10427 go-plus.json http://purl.obolibrary.org/obo/GO_0102046 CHEBI:83943 biolink:ChemicalSubstance L-alanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83943 GO:0102049 biolink:MolecularActivity indole-3-acetyl-methionine synthetase activity Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10431 go-plus.json http://purl.obolibrary.org/obo/GO_0102049 CHEBI:83942 biolink:ChemicalSubstance N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl)-D-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83942 GO:0102048 biolink:MolecularActivity indole-3-acetyl-isoleucine synthetase activity Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10430 go-plus.json http://purl.obolibrary.org/obo/GO_0102048 CHEBI:83941 biolink:ChemicalSubstance N-acetyl-D-muramoyl-L-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83941 chebi_ph7_3 CHEBI:83940 biolink:ChemicalSubstance 1-stearoyl-2-acyl-sn-glycero-3-phospho-(1D-myo-inositol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83940 chebi_ph7_3 CHEBI:34939 biolink:ChemicalSubstance prostaglandin D3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_34939 PO:0005679 biolink:OntologyClass epidermis A portion of plant tissue (PO:0009007) composed of epidermal cells (PO:0004013) that develops from the protoderm (PO:0006210) and covers the surface of a plant structure (PO:0009011). go-plus.json portion of epidermal tissue (exact)|表皮 (Japanese, exact)|epidermides (exact, plural)|multiseriate epidermis (related)|dermal tissue (exact)|epidermises (exact, plural)|epidermal layer (exact)|epidermis (Spanish, exact) http://purl.obolibrary.org/obo/PO_0005679 GO:0102050 biolink:MolecularActivity indole-3-acetyl-tyrosine synthetase activity Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10432 go-plus.json http://purl.obolibrary.org/obo/GO_0102050 GO:0102052 biolink:MolecularActivity indole-3-acetyl-proline synthetase activity Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10434 go-plus.json http://purl.obolibrary.org/obo/GO_0102052 GO:0102051 biolink:MolecularActivity indole-3-acetyl-tryptophan synthetase activity Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10433 go-plus.json http://purl.obolibrary.org/obo/GO_0102051 GO:0102054 biolink:MolecularActivity maleylpyruvate hydrolase activity Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate. RHEA:47956|MetaCyc:RXN-10447 go-plus.json http://purl.obolibrary.org/obo/GO_0102054 GO:0102053 biolink:MolecularActivity (-)-jasmonoyl-isoleucine synthetase activity Catalysis of the reaction: (-)-jasmonate + L-isoleucine + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid. MetaCyc:RXN-10435 go-plus.json http://purl.obolibrary.org/obo/GO_0102053 GO:0102056 biolink:MolecularActivity 11-hydroxyjasmonate sulfotransferase activity Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate. MetaCyc:RXN-10453|RHEA:52732|EC:2.8.2.39 go-plus.json http://purl.obolibrary.org/obo/GO_0102056 CHEBI:83958 biolink:ChemicalSubstance (2E,6E,10E)-omega-hydroxyfarnesyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83958 chebi_ph7_3 CHEBI:83957 biolink:ChemicalSubstance 1-O-(1,2-saturated-alkyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_83957 chebi_ph7_3 UBERON:0015172 biolink:AnatomicalEntity endometrial blood vessel A blood vessel that is part of a endometrium. go-plus.json blood vessel of endometrium http://purl.obolibrary.org/obo/UBERON_0015172 GO:0102055 biolink:MolecularActivity 12-hydroxyjasmonate sulfotransferase activity Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate. MetaCyc:RXN-10451|RHEA:52728|EC:2.8.2.39 go-plus.json http://purl.obolibrary.org/obo/GO_0102055 GO:0102058 biolink:MolecularActivity jasmonoyl-leucine synthetase activity Catalysis of the reaction: L-leucine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine. MetaCyc:RXN-10459 go-plus.json http://purl.obolibrary.org/obo/GO_0102058 CHEBI:83955 biolink:ChemicalSubstance 2-saturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83955 chebi_ph7_3 GO:0102057 biolink:MolecularActivity jasmonoyl-valine synthetase activity Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine. MetaCyc:RXN-10457 go-plus.json http://purl.obolibrary.org/obo/GO_0102057 GO:0102059 biolink:MolecularActivity 2-cis,6-cis-farnesyl pyrophosphate synthase activity Catalysis of the reaction: dimethylallyl diphosphate + 2 isopentenyl diphosphate <=> 2 diphosphate + (2Z,6Z)-farnesyl diphosphate. MetaCyc:RXN-11973|MetaCyc:RXN-10481|RHEA:27810|EC:2.5.1.92 go-plus.json neryl-diphosphate:isopentenyl-diphosphate cistransferase activity http://purl.obolibrary.org/obo/GO_0102059 CHEBI:83953 biolink:ChemicalSubstance omega-hydroxygeranylgeraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_83953 chebi_ph7_3 CHEBI:83952 biolink:ChemicalSubstance (2E,6E,10E)-geranylgeranate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83952 chebi_ph7_3 UBERON:0015179 biolink:AnatomicalEntity somite boundary epithelium Epithelium located in the intersomitic region. go-plus.json intersomitic epithelium|intersomitic membrane http://purl.obolibrary.org/obo/UBERON_0015179 CHEBI:34905 biolink:ChemicalSubstance paraquat go-plus.json http://purl.obolibrary.org/obo/CHEBI_34905 chebi_ph7_3 UBERON:0015178 biolink:AnatomicalEntity somite border A region of somite adjacent to presomitic mesoderm. go-plus.json intersomitic junction|intersomitic boundary|segmental border|inter-somited border|somite boundary|intersomitic fissure http://purl.obolibrary.org/obo/UBERON_0015178 CHEBI:83951 biolink:ChemicalSubstance (2E,6E,10E)-omega-hydroxyfarnesol go-plus.json http://purl.obolibrary.org/obo/CHEBI_83951 chebi_ph7_3 CHEBI:10979 biolink:ChemicalSubstance (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_10979 chebi_ph7_3 CHEBI:10970 biolink:ChemicalSubstance (R)-2-benzylsuccinyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_10970 GO:0102061 biolink:MolecularActivity endo-beta-bergamotene synthase activity Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid. MetaCyc:RXN-10483|RHEA:30467|EC:4.2.3.53 go-plus.json endo-beta-bergamontene synthase activity|(2Z,6Z)-farnesyl diphosphate <=> (+)-endo-beta-bergamotene|(+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) http://purl.obolibrary.org/obo/GO_0102061 GO:0102060 biolink:MolecularActivity endo-alpha-bergamotene synthase activity Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid. RHEA:30471|MetaCyc:RXN-10482|EC:4.2.3.54 go-plus.json endo-alpha-bergamontene synthase activity http://purl.obolibrary.org/obo/GO_0102060 GO:0102063 biolink:MolecularActivity beta-curcumene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene. MetaCyc:RXN-10598 go-plus.json http://purl.obolibrary.org/obo/GO_0102063 GO:0102062 biolink:MolecularActivity alpha-santalene synthase activity Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid. EC:4.2.3.50|MetaCyc:RXN-10567|RHEA:30463 go-plus.json http://purl.obolibrary.org/obo/GO_0102062 UBERON:0015165 biolink:AnatomicalEntity multi-unit eye An eye consisting of multiple light-sensing organs go-plus.json http://purl.obolibrary.org/obo/UBERON_0015165 GO:0102065 biolink:MolecularActivity patchoulene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene. MetaCyc:RXN-10602 go-plus.json http://purl.obolibrary.org/obo/GO_0102065 GO:0102064 biolink:MolecularActivity gamma-curcumene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid. EC:4.2.3.94|RHEA:32031|MetaCyc:RXN-10599 go-plus.json http://purl.obolibrary.org/obo/GO_0102064 GO:0102067 biolink:MolecularActivity geranylgeranyl diphosphate reductase activity Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+. RHEA:26229|EC:1.3.1.83|MetaCyc:RXN-10625 go-plus.json http://purl.obolibrary.org/obo/GO_0102067 CHEBI:83969 biolink:ChemicalSubstance 3-methylpalmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83969 chebi_ph7_3 UBERON:0015161 biolink:AnatomicalEntity inferior branch of oculomotor nerve The inferior branch of the oculomotor nerve or the inferior division, the larger, divides into three branches. One passes beneath the optic nerve to the medial rectus. Another, to the inferior rectus. The third and longest runs forward between the inferior recti and lateralis to the inferior oblique. From the last a short thick branch is given off to the lower part of the ciliary ganglion, and forms its short root. All these branches enter the muscles on their ocular surfaces, with the exception of the nerve to the inferior oblique, which enters the muscle at its posterior border. go-plus.json ventral ramus of occulomotor nerve|ventral ramus of oculomotor nerve|ramus inferior nervi oculomotorii|ramus inferior (nervus oculomotorius [III])|inferior ramus of oculomotor nerve|ramus inferior nervus oculomotorii|inferior division of oculomotor nerve|oculomotor nerve inferior division http://purl.obolibrary.org/obo/UBERON_0015161 GO:0102066 biolink:MolecularActivity alpha-patchoulene synthase activityy Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene. MetaCyc:RXN-10603 go-plus.json http://purl.obolibrary.org/obo/GO_0102066 CHEBI:83968 biolink:ChemicalSubstance 3-methyl fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83968 chebi_ph7_3 GO:0102069 biolink:MolecularActivity zerumbone synthase activity Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+. MetaCyc:RXN-10629|EC:1.1.1.326|RHEA:32327 go-plus.json http://purl.obolibrary.org/obo/GO_0102069 GO:0102068 biolink:MolecularActivity alpha-humulene 10-hydroxylase activity Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O. MetaCyc:RXN-10628|RHEA:32491|EC:1.14.14.113 go-plus.json http://purl.obolibrary.org/obo/GO_0102068 CHEBI:34911 biolink:ChemicalSubstance permethrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_34911 chebi_ph7_3 CHEBI:83966 biolink:ChemicalSubstance D-arginine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83966 CHEBI:83965 biolink:ChemicalSubstance L-arginine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83965 CHEBI:10965 biolink:ChemicalSubstance (R)-2,3,4,5-tetrahydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_10965 chebi_ph7_3 CHEBI:83963 biolink:ChemicalSubstance 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronate)-4-O-sulfonato-D-galactopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83963 chebi_ph7_3 CHEBI:83960 biolink:ChemicalSubstance N(omega)-alpha-(ADP-D-ribosyl)-L-arginine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83960 chebi_ph7_3 GO:0102070 biolink:MolecularActivity 18-hydroxyoleate peroxygenase activity Catalysis of the reaction: 18-hydroxyoleate + a lipid hydroperoxide <=> 9,10-epoxy-18-hydroxystearate + a lipid alcohol. MetaCyc:RXN-1064|EC:1.11.2.3 go-plus.json http://purl.obolibrary.org/obo/GO_0102070 GO:0043050 biolink:BiologicalProcess pharyngeal pumping The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes. go-plus.json pumping behavior http://purl.obolibrary.org/obo/GO_0043050 GO:0008729 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008729 GO:0008728 biolink:MolecularActivity GTP diphosphokinase activity Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate. RHEA:22088|MetaCyc:GTPPYPHOSKIN-RXN|EC:2.7.6.5 go-plus.json GPSII|guanosine 3',5'-polyphosphate synthase activity|ppGpp synthetase I activity|GPSI|ATP:GTP 3'-diphosphotransferase activity|(p)ppGpp synthetase II|guanosine pentaphosphate synthetase activity|guanosine 5',3'-polyphosphate synthetase activity|stringent factor activity|GTP pyrophosphokinase activity|ATP-GTP 3'-diphosphotransferase activity|(p)ppGpp synthetase I http://purl.obolibrary.org/obo/GO_0008728 GO:0008727 biolink:MolecularActivity GDP-mannose mannosyl hydrolase activity Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+. RHEA:28102|MetaCyc:GDPMANMANHYDRO-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008727 GO:0043052 biolink:BiologicalProcess thermotaxis The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature. Wikipedia:Thermotaxis go-plus.json taxis in response to temperature stimulus http://purl.obolibrary.org/obo/GO_0043052 GO:0008726 biolink:MolecularActivity alkanesulfonate monooxygenase activity Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN. RHEA:23064|EC:1.14.14.5|MetaCyc:RXN0-280 go-plus.json FMNH(2)-dependent aliphatic sulfonate monooxygenase activity|alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity|SsuD|alkanesulphonate monooxygenase activity|FMNH2-dependent aliphatic sulfonate monooxygenase activity|FMNH(2)-dependent alkanesulfonate monooxygenase activity|sulfate starvation-induced protein 6 activity http://purl.obolibrary.org/obo/GO_0008726 GO:0043051 biolink:BiologicalProcess regulation of pharyngeal pumping Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes. go-plus.json http://purl.obolibrary.org/obo/GO_0043051 GO:0008725 biolink:MolecularActivity DNA-3-methyladenine glycosylase activity Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site. MetaCyc:3.2.2.21-RXN|MetaCyc:3.2.2.20-RXN|EC:3.2.2.21|EC:3.2.2.20 go-plus.json 3-methyladenine DNA glycosylase I|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA-3-methyladenine glycosidase I activity|deoxyribonucleate 3-methyladenine glycosidase I|DNA-3-methyladenine glycosylase I activity|DNA glycosidase I activity http://purl.obolibrary.org/obo/GO_0008725 GO:0008724 biolink:MolecularActivity obsolete DNA topoisomerase IV activity OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo. go-plus.json DNA topoisomerase IV activity http://purl.obolibrary.org/obo/GO_0008724 GO:0008723 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008723 UBERON:0005749 biolink:AnatomicalEntity glomerular tuft The capillary loops of the kidney that normally function as a filtration unit[MP]. go-plus.json glomerular capillary tuft|glomerulus http://purl.obolibrary.org/obo/UBERON_0005749 GO:0008722 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008722 GO:0008721 biolink:MolecularActivity D-serine ammonia-lyase activity Catalysis of the reaction: D-serine = pyruvate + NH3. Reactome:R-HSA-9034539|Reactome:R-HSA-9014741|MetaCyc:DSERDEAM-RXN|EC:4.3.1.18|RHEA:13977 go-plus.json D-serine ammonia-lyase (pyruvate-forming)|D-serine hydro-lyase (deaminating) activity|D-serine dehydratase activity|D-serine deaminase activity|D-hydroxyaminoacid dehydratase activity|D-serine dehydration activity|D-serine dehydrase activity|D-serine dehydratase (deaminating) activity|D-hydroxy amino acid dehydratase activity|D-serine hydrolase activity http://purl.obolibrary.org/obo/GO_0008721 GO:0043058 biolink:BiologicalProcess regulation of backward locomotion Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0043058 GO:0008720 biolink:MolecularActivity D-lactate dehydrogenase activity Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate. MetaCyc:DLACTDEHYDROGNAD-RXN|EC:1.1.1.28|KEGG_REACTION:R00704|RHEA:16369 go-plus.json D-lactic acid dehydrogenase activity|D-lactic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008720 GO:0043057 biolink:BiologicalProcess backward locomotion Posterior movement of an organism, e.g. following the direction of the tail of an animal. go-plus.json http://purl.obolibrary.org/obo/GO_0043057 GO:0043059 biolink:BiologicalProcess regulation of forward locomotion Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0043059 GO:0043054 biolink:BiologicalProcess dauer exit Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development. go-plus.json exit from nematode dormancy http://purl.obolibrary.org/obo/GO_0043054 GO:0043053 biolink:BiologicalProcess dauer entry Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development. go-plus.json nematode entry into dormancy http://purl.obolibrary.org/obo/GO_0043053 GO:0043056 biolink:BiologicalProcess forward locomotion Anterior movement of an organism, following the direction of the head of the animal. go-plus.json http://purl.obolibrary.org/obo/GO_0043056 GO:0043055 biolink:BiologicalProcess maintenance of dauer Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development. go-plus.json maintenance of dormancy in the nematode http://purl.obolibrary.org/obo/GO_0043055 UBERON:0005754 biolink:AnatomicalEntity rostral part of nephrogenic cord The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005754 UBERON:0005753 biolink:AnatomicalEntity caudal part of nephrogenic cord The metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm. go-plus.json rear portion of nephrogenic cord|caudal portion of nephrogenic cord|caudal region of nephrogenic cord|rear part of nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0005753 GO:0043061 biolink:BiologicalProcess meiotic metaphase II plate congression The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II. go-plus.json http://purl.obolibrary.org/obo/GO_0043061 GO:0008739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008739 GO:0043060 biolink:BiologicalProcess meiotic metaphase I plate congression The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0043060 GO:0008738 biolink:MolecularActivity L-fuculose-phosphate aldolase activity Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate. EC:4.1.2.17|RHEA:12933|KEGG_REACTION:R02262|MetaCyc:FUCPALDOL-RXN go-plus.json L-fuculose-1-phosphate lactaldehyde-lyase activity|L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|L-fuculose 1-phosphate aldolase activity|fuculose aldolase activity http://purl.obolibrary.org/obo/GO_0008738 GO:0043063 biolink:BiologicalProcess intercellular bridge organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another. go-plus.json intercellular bridge organization and biogenesis|intercellular bridge organisation http://purl.obolibrary.org/obo/GO_0043063 GO:0008737 biolink:MolecularActivity L-fuculokinase activity Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+). MetaCyc:FUCULOKIN-RXN|RHEA:12376|EC:2.7.1.51|KEGG_REACTION:R03241 go-plus.json L-fuculose kinase activity|ATP:L-fuculose 1-phosphotransferase activity|L-fuculokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0008737 GO:0043062 biolink:BiologicalProcess extracellular structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. go-plus.json extracellular structure organisation|extracellular structure organization and biogenesis http://purl.obolibrary.org/obo/GO_0043062 goslim_pir GO:0008736 biolink:MolecularActivity L-fucose isomerase activity Catalysis of the reaction: L-fucose = L-fuculose. EC:5.3.1.25|MetaCyc:FUCISOM-RXN|RHEA:17233 go-plus.json L-fucose ketol-isomerase activity|L-fucose aldose-ketose-isomerase activity http://purl.obolibrary.org/obo/GO_0008736 GO:0008735 biolink:MolecularActivity carnitine dehydratase activity Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O. KEGG_REACTION:R01925|EC:4.2.1.89|MetaCyc:CARNDEHYDRA-RXN|RHEA:14577 go-plus.json L-carnitine dehydratase activity|L-carnitine hydro-lyase activity|L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming] http://purl.obolibrary.org/obo/GO_0008735 GO:0008734 biolink:MolecularActivity L-aspartate oxidase activity Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide. EC:1.4.3.16|MetaCyc:L-ASPARTATE-OXID-RXN|MetaCyc:RXN-9772|RHEA:25876 go-plus.json L-aspartate:oxygen oxidoreductase http://purl.obolibrary.org/obo/GO_0008734 GO:0008733 biolink:MolecularActivity L-arabinose isomerase activity Catalysis of the reaction: L-arabinose = L-ribulose. RHEA:14821|KEGG_REACTION:R01761|MetaCyc:ARABISOM-RXN|EC:5.3.1.4 go-plus.json L-arabinose aldose-ketose-isomerase activity|L-arabinose ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0008733 GO:0008732 biolink:MolecularActivity L-allo-threonine aldolase activity Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde. RHEA:26209|MetaCyc:LTAA-RXN|EC:4.1.2.49 go-plus.json L-allo-threonine acetaldehyde-lyase activity|LtaA http://purl.obolibrary.org/obo/GO_0008732 GO:0043069 biolink:BiologicalProcess negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. go-plus.json down-regulation of programmed cell death|inhibition of programmed cell death|down regulation of programmed cell death|negative regulation of non-apoptotic programmed cell death|downregulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043069 GO:0043068 biolink:BiologicalProcess positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. go-plus.json activation of programmed cell death|stimulation of programmed cell death|up-regulation of programmed cell death|upregulation of programmed cell death|positive regulation of non-apoptotic programmed cell death|up regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043068 GO:0008731 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008731 GO:0008730 biolink:MolecularActivity L(+)-tartrate dehydratase activity Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate. EC:4.2.1.32|RHEA:15413|MetaCyc:LTARTDEHYDRA-RXN|KEGG_REACTION:R00339 go-plus.json L-(+)-tartaric acid dehydratase activity|(R,R)-tartrate hydro-lyase activity|tartrate dehydratase activity|L-tartrate dehydratase activity|(R,R)-tartrate hydro-lyase (oxaloacetate-forming)|tartaric acid dehydrase activity http://purl.obolibrary.org/obo/GO_0008730 GO:0043065 biolink:BiologicalProcess positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. go-plus.json pro-apoptosis|up-regulation of apoptosis|upregulation of apoptosis|positive regulation of apoptosis|up regulation of apoptosis|activation of apoptosis|stimulation of apoptosis http://purl.obolibrary.org/obo/GO_0043065 goslim_chembl GO:0043064 biolink:BiologicalProcess obsolete flagellum organization OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum, a long thin projection from a cell, used in movement. go-plus.json flagellum organisation|flagellum organization|flagellum organization and biogenesis http://purl.obolibrary.org/obo/GO_0043064 GO:0043067 biolink:BiologicalProcess regulation of programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. go-plus.json regulation of non-apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0043067 GO:0043066 biolink:BiologicalProcess negative regulation of apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. go-plus.json down-regulation of apoptosis|apoptosis inhibitor activity|inhibition of apoptosis|anti-apoptosis|down regulation of apoptosis|downregulation of apoptosis|negative regulation of apoptosis|pro-survival http://purl.obolibrary.org/obo/GO_0043066 CHEBI:138518 biolink:ChemicalSubstance dialkyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138518 chebi_ph7_3 NCBITaxon:7148 biolink:OrganismalEntity Nematocera go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7148 NCBITaxon:7147 biolink:OrganismalEntity Diptera go-plus.json flies|flies http://purl.obolibrary.org/obo/NCBITaxon_7147 UBERON:0005745 biolink:AnatomicalEntity optic foramen An opening in the skull through which cranial nerve II passes.[MP]. go-plus.json optic canal|optic nerve (II) foramen|optic nerve foramen|optic foramen|canalis opticus|foramen opticum ossis sphenoidalis http://purl.obolibrary.org/obo/UBERON_0005745 UBERON:0005744 biolink:AnatomicalEntity bone foramen Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves. go-plus.json foramen http://purl.obolibrary.org/obo/UBERON_0005744 UBERON:0005742 biolink:AnatomicalEntity adventitia An outermost connective tissue covering of an organ, vessel, or other structure[WP]. go-plus.json tunica advetitia|tunica externa http://purl.obolibrary.org/obo/UBERON_0005742 UBERON:0005740 biolink:AnatomicalEntity tunica intima of artery A tunica intima that is part of a artery. go-plus.json tunica interna (intima)(arteriae)|arterial intima http://purl.obolibrary.org/obo/UBERON_0005740 GO:0008707 biolink:MolecularActivity 4-phytase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate. MetaCyc:6-PHYT-RXN|EC:3.1.3.26|RHEA:20960 go-plus.json 6-phytase activity|phytase activity|6-phytase (name based on 1L-numbering system and not 1D-numbering)|myo-inositol-hexakisphosphate 6-phosphohydrolase activity|phytate 6-phosphatase activity http://purl.obolibrary.org/obo/GO_0008707 GO:0043072 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043072 GO:0008706 biolink:MolecularActivity 6-phospho-beta-glucosidase activity Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose. RHEA:10772|MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN|EC:3.2.1.86 go-plus.json 6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity|phospho-beta-glucosidase activity|phospho-beta-glucosidase A|phosphocellobiase activity http://purl.obolibrary.org/obo/GO_0008706 GO:0043071 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043071 GO:0008705 biolink:MolecularActivity methionine synthase activity Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine. RHEA:11172|MetaCyc:HOMOCYSMETB12-RXN|Reactome:R-HSA-174374|KEGG_REACTION:R00946|EC:2.1.1.13|Reactome:R-HSA-3149539 go-plus.json vitamin B12 methyltransferase activity|methionine synthase (cobalamin-dependent) activity|N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity|5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity|MetH|methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity|tetrahydropteroylglutamic methyltransferase activity|N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity|5-methyltetrahydrofolate-homocysteine S-methyltransferase activity|5-methyltetrahydrofolate--homocysteine transmethylase activity|5-methyltetrahydrofolate--homocysteine S-methyltransferase activity|B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity|N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity|N-methyltetrahydrofolate:L-homocysteine methyltransferase activity|N(5)-methyltetrahydrofolate methyltransferase activity|tetrahydrofolate methyltransferase activity|B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity|cobalamin-dependent methionine synthase activity|tetrahydropteroylglutamate methyltransferase activity|N5-methyltetrahydrofolate methyltransferase activity|N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity http://purl.obolibrary.org/obo/GO_0008705 GO:0043074 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043074 GO:0008704 biolink:MolecularActivity 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate. EC:5.3.3.10|MetaCyc:5.3.3.10-RXN|UM-BBD_reactionID:r0366|RHEA:18813 go-plus.json hpaG1|2-hydroxyhepta-2,4-diene-1,7-dioate isomerase|5-carboxymethyl-2-hydroxymuconic acid isomerase activity|HHDD isomerase activity|5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity|5-carboxymethyl-2-hydroxymuconate D-isomerase activity|hpaG-1|CHM isomerase activity http://purl.obolibrary.org/obo/GO_0008704 GO:0043073 biolink:CellularComponent germ cell nucleus The nucleus of a germ cell, a reproductive cell in multicellular organisms. go-plus.json germ-cell nucleus http://purl.obolibrary.org/obo/GO_0043073 GO:0008703 biolink:MolecularActivity 5-amino-6-(5-phosphoribosylamino)uracil reductase activity Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH. MetaCyc:RIBOFLAVINSYNREDUC-RXN|EC:1.1.1.193|KEGG_REACTION:R03458|RHEA:17845 go-plus.json 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity|aminodioxyphosphoribosylaminopyrimidine reductase activity|5-amino-6-(5'-phosphoribosylamino)uracil reductase activity http://purl.obolibrary.org/obo/GO_0008703 UBERON:0005729 biolink:AnatomicalEntity pectoral appendage field A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme. go-plus.json pectoral appendage field of lateral plate mesoderm|pectoral fin field http://purl.obolibrary.org/obo/UBERON_0005729 GO:0008702 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008702 UBERON:0005728 biolink:AnatomicalEntity extraembryonic mesoderm . go-plus.json extraembryonic mesenchyme|extra-embryonic mesoderm http://purl.obolibrary.org/obo/UBERON_0005728 GO:0008701 biolink:MolecularActivity 4-hydroxy-2-oxovalerate aldolase activity Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate. UM-BBD_enzymeID:e0077|EC:4.1.3.39|RHEA:22624|KEGG_REACTION:R00750|MetaCyc:MHPELY-RXN go-plus.json 4-hydroxy-2-oxopentanoate pyruvate-lyase activity|4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity|4-hydroxy-2-oxovalerate pyruvate-lyase activity|DmpG|4-hydroxy-2-ketovalerate aldolase activity|HOA http://purl.obolibrary.org/obo/GO_0008701 GO:0043070 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043070 GO:0008700 biolink:MolecularActivity 4-hydroxy-2-oxoglutarate aldolase activity Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. RHEA:18169|Reactome:R-HSA-6784423|EC:4.1.3.16|MetaCyc:4OH2OXOGLUTARALDOL-RXN go-plus.json KHG-aldolase activity|4-hydroxy-2-ketoglutarate aldolase activity|hydroxyketoglutarate aldolase activity|hydroxyketoglutaric aldolase activity|4-hydroxy-2-ketoglutaric aldolase activity|DL-4-hydroxy-2-ketoglutarate aldolase activity|2-keto-4-hydroxybutyrate aldolase activity|2-keto-4-hydroxyglutaric aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase activity|2-oxo-4-hydroxyglutarate aldolase activity|2-oxo-4-hydroxyglutaric aldolase activity|2-keto-4-hydroxyglutarate aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming) http://purl.obolibrary.org/obo/GO_0008700 UBERON:0005726 biolink:AnatomicalEntity chemosensory system go-plus.json http://purl.obolibrary.org/obo/UBERON_0005726 GO:0043079 biolink:CellularComponent antipodal cell nucleus The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents. go-plus.json http://purl.obolibrary.org/obo/GO_0043079 GO:0043076 biolink:CellularComponent megasporocyte nucleus The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents. go-plus.json megaspore mother cell nucleus http://purl.obolibrary.org/obo/GO_0043076 GO:0043075 biolink:CellularComponent obsolete sperm cell nucleus (sensu Magnoliophyta) OBSOLETE. The nucleus of a plant pollen cell, the male gamete, and its descendents. go-plus.json sperm cell nucleus (sensu Magnoliophyta)|pollen germ-cell nucleus|pollen germ cell nucleus http://purl.obolibrary.org/obo/GO_0043075 GO:0043078 biolink:CellularComponent polar nucleus Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0043078 GO:0043077 biolink:BiologicalProcess initiation of acetate catabolic process The activation of the chemical reactions and pathways resulting in the breakdown of acetate. go-plus.json initiation of acetate degradation|initiation of acetate breakdown|initiation of acetate catabolism http://purl.obolibrary.org/obo/GO_0043077 CHEBI:2311 biolink:ChemicalSubstance Oplophorus luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_2311 chebi_ph7_3 UBERON:0005734 biolink:AnatomicalEntity tunica adventitia of blood vessel The outermost layer of a blood vessel, composed mainly of fibrous tissue. go-plus.json tunica externa vasorum|external coat|tunica adventitia|tunica adventitia of vessel|tunica adventitia vasorum|adventitia externa http://purl.obolibrary.org/obo/UBERON_0005734 UBERON:0005733 biolink:AnatomicalEntity limb field A ring of cells capable of forming a limb. go-plus.json limb field of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005733 UBERON:0005732 biolink:AnatomicalEntity paired limb/fin field A ring of cells capable of forming a limb or paired fin[Gilbert,modified]. go-plus.json limb/fin field of lateral plate mesoderm|paired limb/fin field http://purl.obolibrary.org/obo/UBERON_0005732 UBERON:0005731 biolink:AnatomicalEntity fin field A limb/fin field that has_potential_to_developmentally_contribute_to a paired fin bud. go-plus.json fin field of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005731 GO:0008709 biolink:MolecularActivity cholate 7-alpha-dehydrogenase activity Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH. KEGG_REACTION:R02792|EC:1.1.1.159|MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN|RHEA:19409 go-plus.json 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity|7alpha-HSDH|7alpha-hydroxy steroid dehydrogenase activity|7-alpha-hydroxysteroid dehydrogenase activity|7alpha-hydroxysteroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008709 UBERON:0005730 biolink:AnatomicalEntity pelvic appendage field A limb/fin field that has the potential to develop into a pelvic appendage bud mesenchyme. go-plus.json pelvic appendage field of lateral plate mesoderm|pelvic fin field http://purl.obolibrary.org/obo/UBERON_0005730 GO:0008708 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008708 GO:0043083 biolink:CellularComponent synaptic cleft The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. NIF_Subcellular:sao243541954 go-plus.json http://purl.obolibrary.org/obo/GO_0043083 goslim_synapse GO:0008718 biolink:MolecularActivity D-amino-acid dehydrogenase activity Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. RHEA:18125|MetaCyc:DAADEHYDROG-RXN go-plus.json D-amino-acid:acceptor oxidoreductase (deaminating)|D-amino-acid:(acceptor) oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0008718 GO:0008717 biolink:MolecularActivity obsolete D-alanyl-D-alanine endopeptidase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json penicillin-binding protein 8|penicillin-binding protein 7|D-alanyl-D-alanine endopeptidase activity http://purl.obolibrary.org/obo/GO_0008717 GO:0043082 biolink:CellularComponent megagametophyte egg cell nucleus The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0043082 GO:0043085 biolink:BiologicalProcess positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme. go-plus.json up-regulation of metalloenzyme activity|stimulation of metalloenzyme activity|up-regulation of enzyme activity|activation of metalloenzyme activity|positive regulation of metalloenzyme activity|up regulation of metalloenzyme activity|upregulation of enzyme activity|positive regulation of enzyme activity|upregulation of metalloenzyme activity|up regulation of enzyme activity|activation of enzyme activity|stimulation of enzyme activity http://purl.obolibrary.org/obo/GO_0043085 goslim_chembl GO:0008716 biolink:MolecularActivity D-alanine-D-alanine ligase activity Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate. MetaCyc:DALADALALIG-RXN|RHEA:11224|EC:6.3.2.4|KEGG_REACTION:R01150 go-plus.json D-Ala-D-Ala synthetase activity|D-alanyl-D-alanine synthetase activity|alanine:alanine ligase (ADP-forming) activity|alanylalanine synthetase activity|D-alanylalanine synthetase activity|D-alanine:D-alanine ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0008716 GO:0043084 biolink:BiologicalProcess penile erection The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. Wikipedia:Erection#Penile_erection go-plus.json http://purl.obolibrary.org/obo/GO_0043084 GO:0008715 biolink:MolecularActivity CDP-diacylglycerol diphosphatase activity Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+). EC:3.6.1.26|KEGG_REACTION:R01797|MetaCyc:CDPDIGLYPYPHOSPHA-RXN|RHEA:15221 go-plus.json CDP-diacylglycerol phosphatidylhydrolase activity|CDP-diacylglycerol pyrophosphatase activity|cytidine diphosphodiacylglycerol pyrophosphatase activity|CDP diacylglycerol hydrolase activity http://purl.obolibrary.org/obo/GO_0008715 UBERON:0005719 biolink:AnatomicalEntity footplate apical ectodermal ridge An apical ectodermal ridge that is part of a footplate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005719 GO:0008714 biolink:MolecularActivity AMP nucleosidase activity Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine. MetaCyc:AMP-NUCLEOSID-RXN|RHEA:20129|KEGG_REACTION:R00182|EC:3.2.2.4 go-plus.json adenylate nucleosidase activity|adenosine monophosphate nucleosidase activity|AMP phosphoribohydrolase activity http://purl.obolibrary.org/obo/GO_0008714 GO:0008713 biolink:MolecularActivity ADP-heptose-lipopolysaccharide heptosyltransferase activity Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+. RHEA:28538|MetaCyc:RXN0-5061 go-plus.json ADP-heptose:LPS heptosyltransferase activity http://purl.obolibrary.org/obo/GO_0008713 GO:0008712 biolink:MolecularActivity ADP-glyceromanno-heptose 6-epimerase activity Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose. EC:5.1.3.20|RHEA:17577|KEGG_REACTION:R05176|MetaCyc:5.1.3.20-RXN go-plus.json ADPglyceromanno-heptose 6-epimerase activity|ADP-L-glycero-D-manno-heptose 6-epimerase activity http://purl.obolibrary.org/obo/GO_0008712 GO:0043081 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043081 GO:0008711 biolink:MolecularActivity obsolete ADP-L-glycero-D-manno-heptose synthase activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json ADP-L-glycero-D-manno-heptose synthase activity http://purl.obolibrary.org/obo/GO_0008711 GO:0043080 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043080 GO:0008710 biolink:MolecularActivity 8-amino-7-oxononanoate synthase activity Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA. EC:2.3.1.47|RHEA:20712|MetaCyc:7KAPSYN-RXN|KEGG_REACTION:R03210 go-plus.json 8-amino-7-ketopelargonate synthase activity|AONS activity|7-KAP synthetase activity|6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)|7-keto-8-aminopelargonic synthetase activity|7-keto-8-amino-pelargonic acid synthetase activity|7-keto-8-aminopelargonic acid synthetase activity|8-amino-7-oxopelargonate synthase activity http://purl.obolibrary.org/obo/GO_0008710 CHEBI:44348 biolink:ChemicalSubstance N-ethylsuccinimide go-plus.json http://purl.obolibrary.org/obo/CHEBI_44348 chebi_ph7_3 GO:0043087 biolink:BiologicalProcess regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase. go-plus.json regulation of Cdc42 GTPase activity|regulation of Ran GTPase activity|regulation of Ral GTPase activity|regulation of Rho GTPase activity|regulation of ARF GTPase activity|regulation of Rac GTPase activity|regulation of Rab GTPase activity|regulation of Ras GTPase activity|regulation of Rap GTPase activity http://purl.obolibrary.org/obo/GO_0043087 CHEBI:20391 biolink:ChemicalSubstance 4-hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_20391 GO:0043086 biolink:BiologicalProcess negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme. go-plus.json down-regulation of enzyme activity|inhibition of enzyme activity|negative regulation of metalloenzyme activity|down-regulation of metalloenzyme activity|downregulation of metalloenzyme activity|down regulation of enzyme activity|down regulation of metalloenzyme activity|downregulation of enzyme activity|negative regulation of enzyme activity|inhibition of metalloenzyme activity http://purl.obolibrary.org/obo/GO_0043086 CHEBI:44343 biolink:ChemicalSubstance (1R,2S)-1,2-dihydronaphthalene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_44343 chebi_ph7_3 GO:0043089 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043089 GO:0043088 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043088 CHEBI:20392 biolink:ChemicalSubstance 4-hydroxyproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_20392 UBERON:0005725 biolink:AnatomicalEntity olfactory system A sensory system that is capable of olfacttion (the sensory perception of smell). go-plus.json http://purl.obolibrary.org/obo/UBERON_0005725 UBERON:0005724 biolink:AnatomicalEntity roof plate spinal cord region A tissue that is part of a spinal cord and is part of a roof plate. go-plus.json spinal cord roof|roof plate spinal cord|roofplate spinal cord http://purl.obolibrary.org/obo/UBERON_0005724 UBERON:0005723 biolink:AnatomicalEntity floor plate spinal cord region A multi-tissue structure that is part of a spinal cord and is part of a floor plate. go-plus.json floorplate spinal cord|spinal cord floor|floor plate spinal cord http://purl.obolibrary.org/obo/UBERON_0005723 UBERON:0005721 biolink:AnatomicalEntity pronephric mesoderm A mesoderm that has the potential to develop into a pronephros. go-plus.json pronephric bulge|pronephric mesenchyme|pronephric primordium|pronephric anlage http://purl.obolibrary.org/obo/UBERON_0005721 UBERON:0005720 biolink:AnatomicalEntity hindbrain venous system A venous system that is part of a hindbrain. go-plus.json rhombencephalon venous system http://purl.obolibrary.org/obo/UBERON_0005720 GO:0008719 biolink:MolecularActivity dihydroneopterin triphosphate 2'-epimerase activity Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate. MetaCyc:H2NTPEPIM-RXN|RHEA:28346|EC:5.1.99.7 go-plus.json D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity http://purl.obolibrary.org/obo/GO_0008719 GO:0043094 biolink:BiologicalProcess cellular metabolic compound salvage Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0043094 goslim_pir GO:0043093 biolink:BiologicalProcess FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells. Wikipedia:Binary_fission go-plus.json cytokinesis by binary fission|prokaryotic fission|prokaryote-type cytokinesis http://purl.obolibrary.org/obo/GO_0043093 CHEBI:20361 biolink:ChemicalSubstance (4-deoxygluc-4-enosyluronic acid)-(1->3)-N-acetyl-D-galactosamine sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20361 GO:0043096 biolink:BiologicalProcess purine nucleobase salvage Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis. go-plus.json purine base salvage http://purl.obolibrary.org/obo/GO_0043096 GO:0043095 biolink:BiologicalProcess regulation of GTP cyclohydrolase I activity Any process that modulates the activity of the enzyme GTP cyclohydrolase I. go-plus.json http://purl.obolibrary.org/obo/GO_0043095 GO:0043090 biolink:BiologicalProcess amino acid import The directed movement of amino acids into a cell or organelle. go-plus.json amino acid uptake http://purl.obolibrary.org/obo/GO_0043090 GO:0043092 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043092 GO:0043091 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043091 CHEBI:44337 biolink:ChemicalSubstance N-acetyl-L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_44337 chebi_ph7_3 GO:0043098 biolink:BiologicalProcess purine deoxyribonucleoside salvage Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043098 GO:0043097 biolink:BiologicalProcess pyrimidine nucleoside salvage Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043097 GO:0043099 biolink:BiologicalProcess pyrimidine deoxyribonucleoside salvage Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043099 CHEBI:2376 biolink:ChemicalSubstance acarbose go-plus.json http://purl.obolibrary.org/obo/CHEBI_2376 UBERON:0005792 biolink:AnatomicalEntity nephric ridge Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions. go-plus.json nephric cord http://purl.obolibrary.org/obo/UBERON_0005792 UBERON:0005795 biolink:AnatomicalEntity embryonic uterus go-plus.json fetal uterus http://purl.obolibrary.org/obo/UBERON_0005795 UBERON:0005788 biolink:AnatomicalEntity lamina rara interna Layer of the glomerular basement membrane adjacent to the glomerular capillary. go-plus.json lamina interna of glomerular basement membrane|internal layer of glomerular basement membrane http://purl.obolibrary.org/obo/UBERON_0005788 CHEBI:58961 biolink:ChemicalSubstance N-arachidonoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58961 CHEBI:19391 biolink:ChemicalSubstance 2,6-dibromophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_19391 CHEBI:58958 biolink:ChemicalSubstance organosulfate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58958 chebi_ph7_3 CHEBI:20346 biolink:ChemicalSubstance cinnamyl alcohol beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_20346 CHEBI:44313 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44313 CHEBI:44312 biolink:ChemicalSubstance beta-muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44312 CHEBI:58956 biolink:ChemicalSubstance branched-chain saturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58956 CHEBI:58955 biolink:ChemicalSubstance branched-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58955 NCBITaxon:7157 biolink:OrganismalEntity Culicidae go-plus.json mosquitos|mosquitos http://purl.obolibrary.org/obo/NCBITaxon_7157 CHEBI:58954 biolink:ChemicalSubstance straight-chain saturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58954 UBERON:0005777 biolink:AnatomicalEntity glomerular basement membrane the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter go-plus.json glomerular capillary basement membrane|GBM|glomerular filtration membrane http://purl.obolibrary.org/obo/UBERON_0005777 CHEBI:58953 biolink:ChemicalSubstance saturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58953 CHEBI:58951 biolink:ChemicalSubstance short-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58951 chebi_ph7_3 CHEBI:58950 biolink:ChemicalSubstance very long-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58950 chebi_ph7_3 CHEBI:58948 biolink:ChemicalSubstance aryl(methyl)malonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58948 CHEBI:58947 biolink:ChemicalSubstance N-acylhomoserinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58947 chebi_ph7_3 CHEBI:58946 biolink:ChemicalSubstance acyl-CoA oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58946 CHEBI:44303 biolink:ChemicalSubstance L-m-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44303 CHEBI:2365 biolink:ChemicalSubstance (+)-abscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2365 UBERON:0005769 biolink:AnatomicalEntity basement membrane of epithelium An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. go-plus.json basement membrane|membrana basalis|basement membrane of connective tissue http://purl.obolibrary.org/obo/UBERON_0005769 CHEBI:58945 biolink:ChemicalSubstance organophosphate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58945 CHEBI:58944 biolink:ChemicalSubstance dialkyl phosphate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58944 CHEBI:58943 biolink:ChemicalSubstance alpha-amino-acid cation residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_58943 CHEBI:58942 biolink:ChemicalSubstance amino-acid cation residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_58942 CHEBI:58941 biolink:ChemicalSubstance cyclic tetrapyrrole anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58941 NCBITaxon:7165 biolink:OrganismalEntity Anopheles gambiae go-plus.json Anopheles gambiae sensu stricto|Anopheles gambiae S|African malaria mosquito http://purl.obolibrary.org/obo/NCBITaxon_7165 UBERON:0005764 biolink:AnatomicalEntity acellular membrane A acellular anatomical structure that is the bounding layer of a anatomical structure. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005764 NCBITaxon:7164 biolink:OrganismalEntity Anopheles go-plus.json Anopheles http://purl.obolibrary.org/obo/NCBITaxon_7164 CHEBI:19375 biolink:ChemicalSubstance 2,5-dichloro-cis,cis-muconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_19375 chebi_ph7_3 GO:0018250 biolink:BiologicalProcess peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG. RESID:AA0181 go-plus.json peptidyl-dehydroalanine anabolism from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine synthesis from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine formation from peptidyl-tyrosine or peptidyl-serine http://purl.obolibrary.org/obo/GO_0018250 GO:0033889 biolink:MolecularActivity N-sulfoglucosamine-3-sulfatase activity Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin. EC:3.1.6.15|MetaCyc:3.1.6.15-RXN go-plus.json chondroitinsulfatase activity|N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0033889 GO:0033888 biolink:MolecularActivity chondro-6-sulfatase activity Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate. KEGG_REACTION:R03518|RHEA:10536|EC:3.1.6.10|MetaCyc:CHONDRO-6-SULFATASE-RXN go-plus.json 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0033888 GO:0033887 biolink:MolecularActivity chondro-4-sulfatase activity Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate. KEGG_REACTION:R03517|EC:3.1.6.9|RHEA:11444|MetaCyc:CHONDRO-4-SULFATASE-RXN go-plus.json 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0033887 GO:0043212 biolink:MolecularActivity carbohydrate-exporting ABC transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out). go-plus.json carbohydrate-exporting ATPase activity http://purl.obolibrary.org/obo/GO_0043212 GO:0043211 biolink:MolecularActivity ABC-type carbohydrate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane. go-plus.json carbohydrate ABC transporter|ATPase-coupled carbohydrate transmembrane transporter activity|carbohydrate-transporting ATPase activity|ATP-dependent carbohydrate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0043211 GO:0043214 biolink:MolecularActivity ABC-type bacteriocin transporter activity Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. go-plus.json ABC-type bacteriocin transmembrane transporter activity|ATPase-coupled bacteriocin transmembrane transporter activity|bacteriocin ABC transporter http://purl.obolibrary.org/obo/GO_0043214 GO:0043213 biolink:BiologicalProcess bacteriocin transport The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain. go-plus.json http://purl.obolibrary.org/obo/GO_0043213 GO:0043210 biolink:MolecularActivity alkanesulfonate binding Binding to alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. go-plus.json http://purl.obolibrary.org/obo/GO_0043210 CHEBI:2179 biolink:ChemicalSubstance D-fucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_2179 chebi_ph7_3 GO:0043219 biolink:CellularComponent lateral loop Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode. NIF_Subcellular:sao1354781919|NIF_Subcellular:sao1067215520 go-plus.json paranodal loop|Schwann cell paranodal termination|oligodendrocyte paranodal termination http://purl.obolibrary.org/obo/GO_0043219 CHEBI:138589 biolink:ChemicalSubstance pneumocysterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138589 chebi_ph7_3 GO:0018249 biolink:BiologicalProcess protein dehydration The removal of a water group from a protein amino acid. go-plus.json protein amino acid dehydration http://purl.obolibrary.org/obo/GO_0018249 GO:0043216 biolink:MolecularActivity obsolete ATPase-coupled daunorubicin transmembrane transporter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out). RHEA:33147 go-plus.json ATP-dependent daunorubicin transmembrane transporter activity|daunorubicin ABC transporter|daunorubicin-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0043216 GO:0043215 biolink:BiologicalProcess daunorubicin transport The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0043215 GO:0018248 biolink:BiologicalProcess obsolete enzyme active site formation via peptidyl cysteine sulfation OBSOLETE. The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine. go-plus.json enzyme active site formation via S-sulpho-L-cysteine http://purl.obolibrary.org/obo/GO_0018248 GO:0043218 biolink:CellularComponent compact myelin The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs. NIF_Subcellular:sao1123256993 go-plus.json oligodendrocyte compact myelin|Schwann cell compact myelin http://purl.obolibrary.org/obo/GO_0043218 GO:0043217 biolink:BiologicalProcess myelin maintenance The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath. go-plus.json http://purl.obolibrary.org/obo/GO_0043217 GO:0018245 biolink:BiologicalProcess protein O-linked glycosylation via tyrosine The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen. RESID:AA0157 go-plus.json protein amino acid O-linked glycosylation via tyrosine http://purl.obolibrary.org/obo/GO_0018245 GO:0033886 biolink:MolecularActivity cellulose-polysulfatase activity Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin. MetaCyc:3.1.6.7-RXN|EC:3.1.6.7 go-plus.json cellulose-sulfate sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0033886 GO:0033885 biolink:MolecularActivity 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate. EC:3.1.3.76|RHEA:16537|KEGG_REACTION:R07582|MetaCyc:3.1.3.76-RXN go-plus.json sEH|hydroxy fatty acid phosphatase activity|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity|soluble epoxide hydrolase activity|dihydroxy fatty acid phosphatase activity|hydroxy lipid phosphatase activity|lipid-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0033885 GO:0018244 biolink:BiologicalProcess protein N-linked glycosylation via tryptophan The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue. RESID:AA0156 go-plus.json protein amino acid N-linked glycosylation via tryptophan http://purl.obolibrary.org/obo/GO_0018244 CHEBI:138582 biolink:ChemicalSubstance 19-hydroxyprostaglandin I2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138582 GO:0033884 biolink:MolecularActivity obsolete phosphoethanolamine/phosphocholine phosphatase activity OBSOLETE. Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate, and phosphocholine + H2O = choline + phosphate. go-plus.json phosphoethanolamine phosphohydrolase activity|phosphoethanolamine/phosphocholine phosphatase activity|3X11A|PHOSPHO1 http://purl.obolibrary.org/obo/GO_0033884 GO:0018247 biolink:BiologicalProcess protein-phosphoribosyl dephospho-coenzyme A linkage The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position. RESID:AA0167 go-plus.json http://purl.obolibrary.org/obo/GO_0018247 GO:0033883 biolink:MolecularActivity pyridoxal phosphatase activity Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate. RHEA:20533|EC:3.1.3.74|MetaCyc:3.1.3.74-RXN go-plus.json vitamin B6 (pyridoxine) phosphatase activity|PNP phosphatase activity|PLP phosphatase activity|pyridoxal-5'-phosphate phosphohydrolase activity|vitamin B6-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0033883 GO:0018246 biolink:BiologicalProcess protein-coenzyme A linkage The formation of a linkage between a protein amino acid and coenzyme A. go-plus.json http://purl.obolibrary.org/obo/GO_0018246 CHEBI:138588 biolink:ChemicalSubstance (R)-3-hydroxypentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138588 chebi_ph7_3 GO:0018241 biolink:BiologicalProcess protein O-linked glycosylation via hydroxylysine The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine. RESID:AA0153 go-plus.json protein amino acid O-linked glycosylation via hydroxylysine http://purl.obolibrary.org/obo/GO_0018241 GO:0033882 biolink:MolecularActivity choloyl-CoA hydrolase activity Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA. RHEA:14541|MetaCyc:3.1.2.27-RXN|EC:3.1.2.27 go-plus.json peroxisomal acyl-CoA thioesterase 2 activity|choloyl-coenzyme A thioesterase activity|PTE-2|chenodeoxycholoyl-coenzyme A thioesterase activity http://purl.obolibrary.org/obo/GO_0033882 GO:0033881 biolink:MolecularActivity bile-acid-CoA hydrolase activity Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+). MetaCyc:BACOAHYDRO-RXN|RHEA:17693|KEGG_REACTION:R07295|EC:3.1.2.26 go-plus.json bile acid-coenzyme A hydrolase activity|deoxycholoyl-CoA hydrolase activity http://purl.obolibrary.org/obo/GO_0033881 GO:0018240 biolink:BiologicalProcess protein S-linked glycosylation via cysteine The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine. RESID:AA0152 go-plus.json protein amino acid S-linked glycosylation via cysteine http://purl.obolibrary.org/obo/GO_0018240 CHEBI:138587 biolink:ChemicalSubstance (R)-3-hydroxypentanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138587 chebi_ph7_3 GO:0033880 biolink:MolecularActivity phenylacetyl-CoA hydrolase activity Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate. RHEA:15337|MetaCyc:3.1.2.25-RXN|KEGG_REACTION:R07294|EC:3.1.2.25 go-plus.json phenylglyoxylyl-CoA hydrolase activity http://purl.obolibrary.org/obo/GO_0033880 GO:0018243 biolink:BiologicalProcess protein O-linked glycosylation via threonine The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine. RESID:AA0155 go-plus.json protein amino acid O-linked glycosylation via threonine http://purl.obolibrary.org/obo/GO_0018243 GO:0018242 biolink:BiologicalProcess protein O-linked glycosylation via serine The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine. RESID:AA0154 go-plus.json protein amino acid O-linked glycosylation via serine http://purl.obolibrary.org/obo/GO_0018242 GO:0018261 biolink:BiologicalProcess peptidyl-lysine guanylylation The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine. RESID:AA0228 go-plus.json http://purl.obolibrary.org/obo/GO_0018261 GO:0018260 biolink:BiologicalProcess protein guanylylation The addition of phospho-guanosine to a protein amino acid. go-plus.json protein amino acid guanylylation http://purl.obolibrary.org/obo/GO_0018260 GO:0033879 biolink:MolecularActivity acetylajmaline esterase activity Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate. MetaCyc:RXN-8653|MetaCyc:RXN-8652|EC:3.1.1.80 go-plus.json AAE|17-O-acetylajmaline O-acetylhydrolase activity|2beta(R)-17-O-acetylajmalan:acetylesterase activity|acetylajmalan esterase activity http://purl.obolibrary.org/obo/GO_0033879 GO:0033878 biolink:MolecularActivity hormone-sensitive lipase activity Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate. MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|EC:3.1.1.79|MetaCyc:STEROL-ESTERASE-RXN go-plus.json HSL|diacylglycerol acylhydrolase activity http://purl.obolibrary.org/obo/GO_0033878 GO:0033877 biolink:MolecularActivity succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate. MetaCyc:RXN-864|UM-BBD_reactionID:r0329|EC:2.8.3.15|RHEA:16469|KEGG_REACTION:R05588 go-plus.json succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity|benzylsuccinate CoA-transferase activity|succinyl-CoA:benzylsuccinate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0033877 GO:0033876 biolink:MolecularActivity glycochenodeoxycholate sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+). KEGG_REACTION:R07289|MetaCyc:2.8.2.34-RXN|EC:2.8.2.34|RHEA:17689 go-plus.json 3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity|BAST|bile acid:PAPS:sulfotransferase activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity http://purl.obolibrary.org/obo/GO_0033876 GO:0043223 biolink:CellularComponent cytoplasmic SCF ubiquitin ligase complex A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). go-plus.json cytoplasmic cullin complex|cytoplasmic Skp1/Cul1/F-box protein complex|cytoplasmic SCF complex http://purl.obolibrary.org/obo/GO_0043223 GO:0043222 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043222 GO:0043225 biolink:MolecularActivity ATPase-coupled inorganic anion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in). Reactome:R-HSA-5690340|Reactome:R-HSA-1454916 go-plus.json anion transmembrane-transporting ATPase activity|anion-transporting ATPase activity|anion ABC transporter|ATPase-coupled anion transmembrane transporter activity|ATP-dependent anion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0043225 GO:0043224 biolink:CellularComponent nuclear SCF ubiquitin ligase complex A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). go-plus.json nuclear cullin complex|nuclear Skp1/Cul1/F-box protein complex|nuclear SCF complex http://purl.obolibrary.org/obo/GO_0043224 GO:0043221 biolink:MolecularActivity SMC family protein binding Binding to a protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization. go-plus.json structural maintenance of chromosomes family protein binding http://purl.obolibrary.org/obo/GO_0043221 GO:0043220 biolink:CellularComponent Schmidt-Lanterman incisure Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier. NIF_Subcellular:sao254777664 go-plus.json Schmidt-Lanterman cleft http://purl.obolibrary.org/obo/GO_0043220 GO:0043227 biolink:CellularComponent membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. NIF_Subcellular:sao414196390 go-plus.json membrane-enclosed organelle http://purl.obolibrary.org/obo/GO_0043227 GO:0018259 biolink:BiologicalProcess RNA-protein covalent cross-linking via peptidyl-serine The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine. RESID:AA0213 go-plus.json http://purl.obolibrary.org/obo/GO_0018259 GO:0043226 biolink:CellularComponent organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. NIF_Subcellular:sao1539965131|Wikipedia:Organelle go-plus.json http://purl.obolibrary.org/obo/GO_0043226 goslim_generic|goslim_chembl|goslim_pir GO:0043229 biolink:CellularComponent intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0043229 goslim_pir GO:0043228 biolink:CellularComponent non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. NIF_Subcellular:sao1456184038 go-plus.json non-membrane-enclosed organelle|biological condensate http://purl.obolibrary.org/obo/GO_0043228 GO:0018256 biolink:BiologicalProcess protein formylation The addition of a formyl group to a protein amino acid. go-plus.json protein amino acid formylation http://purl.obolibrary.org/obo/GO_0018256 CHEBI:138595 biolink:ChemicalSubstance O-phosphocholine-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138595 chebi_ph7_3 GO:0033875 biolink:BiologicalProcess ribonucleoside bisphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json ribonucleoside bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0033875 GO:0033874 biolink:MolecularActivity scymnol sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+). MetaCyc:2.8.2.32-RXN|KEGG_REACTION:R07798|EC:2.8.2.32|RHEA:15477 go-plus.json http://purl.obolibrary.org/obo/GO_0033874 CHEBI:2181 biolink:ChemicalSubstance L-fucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_2181 chebi_ph7_3 GO:0018255 biolink:BiologicalProcess peptide cross-linking via S-glycyl-L-cysteine The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins. RESID:AA0206 go-plus.json http://purl.obolibrary.org/obo/GO_0018255 GO:0033873 biolink:MolecularActivity petromyzonol sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+). MetaCyc:2.8.2.31-RXN|RHEA:16997|EC:2.8.2.31|KEGG_REACTION:R07797 go-plus.json PZ-SULT|3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity http://purl.obolibrary.org/obo/GO_0033873 GO:0018258 biolink:BiologicalProcess protein O-linked glycosylation via hydroxyproline The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline. RESID:AA0212 go-plus.json protein amino acid O-linked glycosylation via hydroxyproline http://purl.obolibrary.org/obo/GO_0018258 GO:0033872 biolink:MolecularActivity [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. MetaCyc:2.8.2.30-RXN|EC:2.8.2.30 go-plus.json 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|3-OST-3|heparin-glucosamine 3-sulfotransferase 3 activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity|glucosaminyl 3-O-sulfotransferase 3a, 3b activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity|glucosaminyl 3-O-sulfotransferase 3 activity|isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B) http://purl.obolibrary.org/obo/GO_0033872 GO:0018257 biolink:BiologicalProcess peptidyl-lysine formylation The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine. RESID:AA0211 go-plus.json http://purl.obolibrary.org/obo/GO_0018257 GO:0033871 biolink:MolecularActivity [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S. MetaCyc:2.8.2.29-RXN|EC:2.8.2.29 go-plus.json heparin-glucosamine 3-sulfotransferase 2 activity|isoform/isozyme 2 (3-OST-2, HS3ST2)|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|3-OST-2|heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity|glucosaminyl 3-O-sulfotransferase 2 activity http://purl.obolibrary.org/obo/GO_0033871 GO:0018252 biolink:BiologicalProcess peptide cross-linking via L-seryl-5-imidazolinone glycine The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. RESID:AA0184 go-plus.json biosynthetic process of protein-protein cross-link via L-seryl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-seryl-5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0018252 CHEBI:138599 biolink:ChemicalSubstance 4,4'-diapolycopen-4-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_138599 chebi_ph7_3 GO:0033870 biolink:MolecularActivity thiol sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate. MetaCyc:THIOL-SULFOTRANSFERASE-RXN|RHEA:14637|EC:2.8.2.16 go-plus.json PAPS sulfotransferase activity|3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity|adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity http://purl.obolibrary.org/obo/GO_0033870 GO:0018251 biolink:BiologicalProcess peptidyl-tyrosine dehydrogenation The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues. RESID:AA0183 go-plus.json http://purl.obolibrary.org/obo/GO_0018251 GO:0018254 biolink:BiologicalProcess peptidyl-tyrosine adenylylation The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine. RESID:AA0203 go-plus.json peptidyl-tyrosine adenylation http://purl.obolibrary.org/obo/GO_0018254 CHEBI:138597 biolink:ChemicalSubstance (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138597 chebi_ph7_3 GO:0018253 biolink:BiologicalProcess peptide cross-linking via 5-imidazolinone glycine The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde. RESID:AA0188|RESID:AA0187|RESID:AA0184 go-plus.json biosynthesis of protein-protein cross-link via 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 5-imidazolinone glycine http://purl.obolibrary.org/obo/GO_0018253 CHEBI:138596 biolink:ChemicalSubstance (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138596 chebi_ph7_3 GO:0033869 biolink:BiologicalProcess nucleoside bisphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json nucleoside bisphosphate catabolism|nucleoside bisphosphate degradation|nucleoside bisphosphate breakdown http://purl.obolibrary.org/obo/GO_0033869 GO:0033868 biolink:MolecularActivity obsolete Goodpasture-antigen-binding protein kinase activity OBSOLETE. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein. MetaCyc:2.7.11.9-RXN|EC:2.7.11.9 go-plus.json ATP:Goodpasture antigen-binding protein phosphotransferase activity|GPBP kinase activity|GPBPK|Goodpasture antigen-binding protein kinase activity|STK11 http://purl.obolibrary.org/obo/GO_0033868 GO:0033867 biolink:MolecularActivity Fas-activated serine/threonine kinase activity Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein. EC:2.7.11.8|MetaCyc:2.7.11.8-RXN go-plus.json FAST|ATP:Fas-activated serine/threonine protein phosphotransferase activity|FASTK|STK10 http://purl.obolibrary.org/obo/GO_0033867 GO:0033866 biolink:BiologicalProcess nucleoside bisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json nucleoside bisphosphate anabolism|nucleoside bisphosphate formation|nucleoside bisphosphate biosynthesis|nucleoside bisphosphatehate synthesis http://purl.obolibrary.org/obo/GO_0033866 GO:0033865 biolink:BiologicalProcess nucleoside bisphosphate metabolic process The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. go-plus.json nucleoside bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0033865 GO:0043234 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043234 GO:0043233 biolink:CellularComponent organelle lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. go-plus.json http://purl.obolibrary.org/obo/GO_0043233 GO:0043236 biolink:MolecularActivity laminin binding Binding to a laminin, a major glycoprotein constituent of the basement membrane of cells. go-plus.json laminin-4 binding|laminin-2 binding http://purl.obolibrary.org/obo/GO_0043236 GO:0043235 biolink:CellularComponent receptor complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json http://purl.obolibrary.org/obo/GO_0043235 goslim_pir GO:0043230 biolink:CellularComponent extracellular organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0043230 goslim_pir GO:0043232 biolink:CellularComponent intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. go-plus.json intracellular non-membrane-enclosed organelle http://purl.obolibrary.org/obo/GO_0043232 goslim_mouse|goslim_pir GO:0043231 biolink:CellularComponent intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. go-plus.json intracellular membrane-enclosed organelle http://purl.obolibrary.org/obo/GO_0043231 goslim_pir CHEBI:138569 biolink:ChemicalSubstance (3E,5Z)-dodecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138569 chebi_ph7_3 GO:0043238 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043238 GO:0018227 biolink:BiologicalProcess peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine. RESID:AA0103 go-plus.json peptidyl-S-12-hydroxyfarnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018227 GO:0043237 biolink:MolecularActivity laminin-1 binding Binding to laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1. go-plus.json laminin-111 binding http://purl.obolibrary.org/obo/GO_0043237 GO:0018226 biolink:BiologicalProcess peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic. RESID:AA0102 go-plus.json peptidyl-S-farnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018226 GO:0018229 biolink:BiologicalProcess peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester. RESID:AA0105 go-plus.json peptidyl-L-cysteine methyl ester formation from peptidyl-cysteine|peptidyl-L-cysteine methyl ester synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl ester anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018229 GO:0043239 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043239 GO:0018228 biolink:BiologicalProcess peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification. RESID:AA0104 go-plus.json peptidyl-S-geranylgeranyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018228 GO:0033864 biolink:BiologicalProcess positive regulation of NAD(P)H oxidase activity Any process that activates or increases the activity of the enzyme NAD(P)H oxidase. go-plus.json upregulation of NAD(P)H oxidase activity|stimulation of NAD(P)H oxidase activity|up-regulation of NAD(P)H oxidase activity|activation of NAD(P)H oxidase activity|up regulation of NAD(P)H oxidase activity http://purl.obolibrary.org/obo/GO_0033864 GO:0018223 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018223 GO:0018222 biolink:BiologicalProcess peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide. RESID:AA0101 go-plus.json peptidyl-L-cysteine methyl disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide formation from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018222 GO:0033863 biolink:MolecularActivity ribose 1,5-bisphosphate phosphokinase activity Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+). RHEA:20109|KEGG_REACTION:R06836|EC:2.7.4.23|MetaCyc:2.7.4.23-RXN go-plus.json ATP:ribose-1,5-bisphosphate phosphotransferase activity|ribose 1,5-bisphosphokinase activity|PhnN http://purl.obolibrary.org/obo/GO_0033863 GO:0033862 biolink:MolecularActivity UMP kinase activity Catalysis of the reaction: ATP + UMP = ADP + UDP. RHEA:24400|EC:2.7.4.22|MetaCyc:2.7.4.22-RXN go-plus.json UMPK|uridine monophosphate kinase activity|PyrH|ATP:UMP phosphotransferase activity|SmbA|UMP-kinase activity http://purl.obolibrary.org/obo/GO_0033862 CHEBI:138560 biolink:ChemicalSubstance 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_138560 GO:0018225 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018225 CHEBI:2150 biolink:ChemicalSubstance 5beta-dihydrotestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_2150 chebi_ph7_3 GO:0033861 biolink:BiologicalProcess negative regulation of NAD(P)H oxidase activity Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase. go-plus.json inhibition of NAD(P)H oxidase activity|down-regulation of NAD(P)H oxidase activity|downregulation of NAD(P)H oxidase activity|down regulation of NAD(P)H oxidase activity http://purl.obolibrary.org/obo/GO_0033861 GO:0018224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018224 GO:0033860 biolink:BiologicalProcess regulation of NAD(P)H oxidase activity Any process that modulates the activity of the enzyme NAD(P)H oxidase. go-plus.json http://purl.obolibrary.org/obo/GO_0033860 GO:0018221 biolink:BiologicalProcess peptidyl-serine palmitoylation The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine. RESID:AA0080 go-plus.json peptidyl-serine O-palmitoylation http://purl.obolibrary.org/obo/GO_0018221 GO:0018220 biolink:BiologicalProcess peptidyl-threonine palmitoylation The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine. RESID:AA0079 go-plus.json peptidyl-threonine O-palmitoylation http://purl.obolibrary.org/obo/GO_0018220 GO:0033859 biolink:BiologicalProcess furaldehyde metabolic process The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass. go-plus.json http://purl.obolibrary.org/obo/GO_0033859 GO:0033858 biolink:MolecularActivity N-acetylgalactosamine kinase activity Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate. EC:2.7.1.157|RHEA:12617|MetaCyc:2.7.1.157-RXN go-plus.json ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity|GALK2|N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity|GK2|GalNAc kinase activity http://purl.obolibrary.org/obo/GO_0033858 GO:0033857 biolink:MolecularActivity diphosphoinositol-pentakisphosphate kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate. EC:2.7.4.24 go-plus.json VIP2|VIP1|PPIP5K|PPIP5K2|PPIP5K1|PP-InsP5 kinase activity|PP-IP5 kinase activity|ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0033857 GO:0033856 biolink:MolecularActivity pyridoxine 5'-phosphate synthase activity Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate. RHEA:15265|EC:2.6.99.2|MetaCyc:PDXJ-RXN|KEGG_REACTION:R05838 go-plus.json PNP synthase activity|1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity|pyridoxine 5-phosphate phospho lyase activity http://purl.obolibrary.org/obo/GO_0033856 GO:0033855 biolink:MolecularActivity nicotianamine aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate. KEGG_REACTION:R07277|EC:2.6.1.80|MetaCyc:2.6.1.80-RXN|RHEA:22104 go-plus.json NAAT-I|NAAT-III|nicotianamine transaminase activity|NAAT-II|nicotianamine:2-oxoglutarate aminotransferase activity|NAAT http://purl.obolibrary.org/obo/GO_0033855 GO:0033854 biolink:MolecularActivity glutamate-prephenate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate. RHEA:22880|KEGG_REACTION:R07276|MetaCyc:PREPHENATE-TRANSAMINE-RXN|EC:2.6.1.79 go-plus.json L-glutamate:prephenate aminotransferase activity|PAT|prephenate transaminase activity|L-arogenate:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0033854 GO:0043245 biolink:CellularComponent extraorganismal space The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0043245 GO:0043244 biolink:BiologicalProcess regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. go-plus.json regulation of protein complex disassembly http://purl.obolibrary.org/obo/GO_0043244 GO:0043247 biolink:BiologicalProcess telomere maintenance in response to DNA damage Any process that occur in response to the presence of critically short or damaged telomeres. go-plus.json DNA damage response, telomere maintenance http://purl.obolibrary.org/obo/GO_0043247 GO:0043246 biolink:CellularComponent megasome Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex. go-plus.json http://purl.obolibrary.org/obo/GO_0043246 GO:0043241 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043241 GO:0043240 biolink:CellularComponent Fanconi anaemia nuclear complex A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage. go-plus.json Fanconi anaemia complex|FA core complex|FA nuclear complex|FA complex http://purl.obolibrary.org/obo/GO_0043240 GO:0043243 biolink:BiologicalProcess positive regulation of protein-containing complex disassembly Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. go-plus.json upregulation of protein complex disassembly|up regulation of protein complex disassembly|activation of protein complex disassembly|stimulation of protein complex disassembly|positive regulation of protein complex disassembly|up-regulation of protein complex disassembly http://purl.obolibrary.org/obo/GO_0043243 GO:0043242 biolink:BiologicalProcess negative regulation of protein-containing complex disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. go-plus.json down regulation of protein complex disassembly|downregulation of protein complex disassembly|down-regulation of protein complex disassembly|negative regulation of protein complex disassembly|inhibition of protein complex disassembly http://purl.obolibrary.org/obo/GO_0043242 NCBITaxon:200795 biolink:OrganismalEntity Chloroflexi go-plus.json Thermomicrobiota|green nonsulfur bacteria|GNS bacteria|green non-sulfur bacteria|Chloroflexota|Chloroflexaeota|Thermomicrobaeota http://purl.obolibrary.org/obo/NCBITaxon_200795 GO:0043249 biolink:BiologicalProcess erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. go-plus.json RBC maturation|red blood cell maturation http://purl.obolibrary.org/obo/GO_0043249 GO:0018238 biolink:BiologicalProcess peptidyl-lysine carboxyethylation The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine. RESID:AA0115 go-plus.json protein amino acid carboxyethylation http://purl.obolibrary.org/obo/GO_0018238 GO:0043248 biolink:BiologicalProcess proteasome assembly The aggregation, arrangement and bonding together of a mature, active proteasome complex. go-plus.json proteasome maturation|proteasome complex assembly|26S proteasome assembly http://purl.obolibrary.org/obo/GO_0043248 GO:0018237 biolink:MolecularActivity urease activator activity Increases the activity of urease by promoting the incorporation of nickel into the active site. go-plus.json urease activase activity http://purl.obolibrary.org/obo/GO_0018237 GO:0018239 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018239 GO:0018234 biolink:BiologicalProcess peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase. RESID:AA0113 go-plus.json http://purl.obolibrary.org/obo/GO_0018234 GO:0033853 biolink:MolecularActivity aspartate-prephenate aminotransferase activity Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate. MetaCyc:PREPHENATE-ASP-TRANSAMINE-RXN|RHEA:20445|EC:2.6.1.78 go-plus.json L-arogenate:oxaloacetate aminotransferase activity|PAT|L-aspartate:prephenate aminotransferase activity|prephenate aspartate aminotransferase activity|prephenate transaminase activity http://purl.obolibrary.org/obo/GO_0033853 GO:0033852 biolink:MolecularActivity thyroid-hormone transaminase activity Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate. RHEA:19133|EC:2.6.1.26|MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R03952 go-plus.json thyroid hormone aminotransferase activity|3,5-dinitrotyrosine transaminase activity|thyroid-hormone aminotransferase activity|3,5-dinitrotyrosine aminotransferase activity|L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0033852 GO:0018233 biolink:BiologicalProcess peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link. RESID:AA0109 go-plus.json http://purl.obolibrary.org/obo/GO_0018233 GO:0033851 biolink:MolecularActivity lavandulyl diphosphate synthase activity Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate. KEGG_REACTION:R08950|MetaCyc:2.5.1.69-RXN|EC:2.5.1.69|RHEA:21676 go-plus.json dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity|FDS-5 http://purl.obolibrary.org/obo/GO_0033851 GO:0018236 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018236 GO:0033850 biolink:MolecularActivity Z-farnesyl diphosphate synthase activity Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate. MetaCyc:2.5.1.68-RXN|EC:2.5.1.68|KEGG_REACTION:R08528|RHEA:23300 go-plus.json (Z)-farnesyl diphosphate synthase activity|geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity http://purl.obolibrary.org/obo/GO_0033850 GO:0018235 biolink:BiologicalProcess peptidyl-lysine carboxylation The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine. RESID:AA0114 go-plus.json http://purl.obolibrary.org/obo/GO_0018235 GO:0018230 biolink:BiologicalProcess peptidyl-L-cysteine S-palmitoylation The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine. RESID:AA0106 go-plus.json peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-cysteine S-palmitoylation|peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018230 CHEBI:2164 biolink:ChemicalSubstance 6-acetamido-3-aminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2164 GO:0018232 biolink:BiologicalProcess peptide cross-linking via S-(L-isoglutamyl)-L-cysteine The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link. RESID:AA0108 go-plus.json http://purl.obolibrary.org/obo/GO_0018232 GO:0018231 biolink:BiologicalProcess peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids. RESID:AA0107 go-plus.json peptidyl-S-diacylglycerol-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine anabolism from peptidyl-cysteine http://purl.obolibrary.org/obo/GO_0018231 CHEBI:2165 biolink:ChemicalSubstance 6-acetamido-3-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2165 GO:0033849 biolink:MolecularActivity chrysanthemyl diphosphate synthase activity Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate. EC:2.5.1.67|KEGG_REACTION:R08948|RHEA:14009|MetaCyc:2.5.1.67-RXN go-plus.json CPPase activity|dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity http://purl.obolibrary.org/obo/GO_0033849 GO:0043250 biolink:MolecularActivity sodium-dependent organic anion transmembrane transporter activity Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner. go-plus.json http://purl.obolibrary.org/obo/GO_0043250 GO:0033848 biolink:MolecularActivity N2-(2-carboxyethyl)arginine synthase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate. RHEA:10556|EC:2.5.1.66|KEGG_REACTION:R05465|MetaCyc:2.5.1.66-RXN go-plus.json glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|CEAS|N2-(2-carboxyethyl)arginine synthetase activity|glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|CEA synthetase activity http://purl.obolibrary.org/obo/GO_0033848 GO:0033847 biolink:MolecularActivity O-phosphoserine sulfhydrylase activity Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate. EC:2.5.1.65|RHEA:10252|MetaCyc:2.5.1.65-RXN go-plus.json O-phosphoserine(thiol)-lyase activity|O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity http://purl.obolibrary.org/obo/GO_0033847 GO:0033846 biolink:MolecularActivity adenosyl-fluoride synthase activity Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine. MetaCyc:2.5.1.63-RXN|EC:2.5.1.63|RHEA:16661 go-plus.json fluorinase activity|S-adenosyl-L-methionine:fluoride adenosyltransferase activity http://purl.obolibrary.org/obo/GO_0033846 GO:0008889 biolink:MolecularActivity glycerophosphodiester phosphodiesterase activity Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate. EC:3.1.4.46|Reactome:R-HSA-1483107|Reactome:R-HSA-1483116|MetaCyc:GLYCPDIESTER-RXN|RHEA:12969 go-plus.json gene hpd protein|IgD-binding protein D|glycerophosphoryl diester phosphodiesterase activity|glycerophosphodiester glycerophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008889 GO:0033845 biolink:MolecularActivity hydroxymethylfurfural reductase (NADPH) activity Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+. go-plus.json http://purl.obolibrary.org/obo/GO_0033845 UBERON:0005826 biolink:AnatomicalEntity gracile fasciculus of spinal cord A gracile fasciculus that is part of a spinal cord. go-plus.json gracile fascicle of spinal cord|spinal cord segment of fasciculus gracilis|spinal cord segment of gracile fasciculus|fasciculus gracilis (medulla spinalis) http://purl.obolibrary.org/obo/UBERON_0005826 GO:0008888 biolink:MolecularActivity glycerol dehydrogenase [NAD+] activity Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH. RHEA:13769|KEGG_REACTION:R01034|EC:1.1.1.6|MetaCyc:GLYCDEH-RXN go-plus.json NAD-linked glycerol dehydrogenase activity|glycerol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008888 GO:0033844 biolink:MolecularActivity galactose-6-sulfurylase activity Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues. MetaCyc:2.5.1.5-RXN|EC:2.5.1.5 go-plus.json galactose-6-sulfatase activity|D-galactose-6-sulfate:alkyltransferase (cyclizing) activity|galactose 6-sulfatase activity|porphyran sulfatase activity http://purl.obolibrary.org/obo/GO_0033844 GO:0008887 biolink:MolecularActivity glycerate kinase activity Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+). RHEA:23516|KEGG_REACTION:R01514|EC:2.7.1.31|Reactome:R-HSA-6799495|MetaCyc:GLY3KIN-RXN go-plus.json D-glyceric acid kinase activity|GK|D-glycerate 3-kinase activity|glycerate-3-kinase activity|D-glycerate kinase activity|glycerate kinase (phosphorylating)|ATP:D-glycerate 2-phosphotransferase activity|ATP:(R)-glycerate 3-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008887 GO:0033843 biolink:MolecularActivity xyloglucan 6-xylosyltransferase activity Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage. EC:2.4.2.39|MetaCyc:2.4.2.39-RXN go-plus.json xyloglucan 6-alpha-D-xylosyltransferase activity|UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity|uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0033843 GO:0043256 biolink:CellularComponent laminin complex A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0043256 goslim_pir GO:0008886 biolink:MolecularActivity glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH. RHEA:14669|KEGG_REACTION:R01058|MetaCyc:1.2.1.9-RXN|EC:1.2.1.9 go-plus.json glyceraldehyde 3-phosphate dehydrogenase (NADP)|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)|NADP-glyceraldehyde phosphate dehydrogenase|glyceraldehyde phosphate dehydrogenase (NADP)|glyceraldehyde-3-phosphate:NADP reductase activity|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity|nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NADP)|NADP-glyceraldehyde-3-phosphate dehydrogenase activity|triosephosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008886 GO:0043255 biolink:BiologicalProcess regulation of carbohydrate biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. go-plus.json regulation of carbohydrate biosynthesis|regulation of carbohydrate anabolism|regulation of carbohydrate synthesis|regulation of carbohydrate formation http://purl.obolibrary.org/obo/GO_0043255 GO:0008885 biolink:MolecularActivity glutathionylspermidine synthase activity Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate. EC:6.3.1.8|RHEA:21272|MetaCyc:GSPSYN-RXN go-plus.json GSP synthetase activity|gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity|gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]|glutathione:spermidine ligase (ADP-forming) activity|glutathionylspermidine synthetase activity http://purl.obolibrary.org/obo/GO_0008885 GO:0008884 biolink:MolecularActivity glutathionylspermidine amidase activity Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine. EC:3.5.1.78|RHEA:17173|MetaCyc:GSPAMID-RXN go-plus.json gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity|glutathionylspermidine amidohydrolase (spermidine-forming) activity|GSP amidase activity http://purl.obolibrary.org/obo/GO_0008884 GO:0043258 biolink:CellularComponent laminin-9 complex A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains. go-plus.json laminin-421 complex http://purl.obolibrary.org/obo/GO_0043258 GO:0043257 biolink:CellularComponent laminin-8 complex A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains. go-plus.json laminin-411 complex http://purl.obolibrary.org/obo/GO_0043257 GO:0008883 biolink:MolecularActivity glutamyl-tRNA reductase activity Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH. EC:1.2.1.70|RHEA:12344|MetaCyc:GLUTRNAREDUCT-RXN|KEGG_REACTION:R04109 go-plus.json L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming) http://purl.obolibrary.org/obo/GO_0008883 GO:0008882 biolink:MolecularActivity [glutamate-ammonia-ligase] adenylyltransferase activity Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. RHEA:18589|EC:2.7.7.42|MetaCyc:GSADENYLATION-RXN go-plus.json glutamate-ammonia-ligase adenylyltransferase activity|ATP:glutamine synthetase adenylyltransferase activity|ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity|ATP:[glutamate-ammonia-ligase] adenylyltransferase activity|glutamine-synthetase adenylyltransferase activity|adenosine triphosphate:glutamine synthetase adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0008882 GO:0043252 biolink:BiologicalProcess sodium-independent organic anion transport The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0043252 GO:0043251 biolink:BiologicalProcess sodium-dependent organic anion transport The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0043251 GO:0008881 biolink:MolecularActivity glutamate racemase activity Catalysis of the reaction: L-glutamate = D-glutamate. KEGG_REACTION:R00260|EC:5.1.1.3|MetaCyc:GLUTRACE-RXN|RHEA:12813 go-plus.json http://purl.obolibrary.org/obo/GO_0008881 GO:0008880 biolink:MolecularActivity glucuronate isomerase activity Catalysis of the reaction: D-glucuronate = D-fructuronate. EC:5.3.1.12|RHEA:13049|MetaCyc:GLUCUROISOM-RXN go-plus.json D-glucuronate ketol-isomerase activity|uronic acid isomerase activity|uronate isomerase activity|uronic isomerase activity|D-glucuronate aldose-ketose-isomerase activity|D-glucuronate isomerase activity http://purl.obolibrary.org/obo/GO_0008880 GO:0043254 biolink:BiologicalProcess regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of protein complex assembly. go-plus.json regulation of protein complex assembly http://purl.obolibrary.org/obo/GO_0043254 GO:0043253 biolink:CellularComponent chloroplast ribosome A ribosome contained within a chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0043253 GO:0018209 biolink:BiologicalProcess peptidyl-serine modification The modification of peptidyl-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0018209 GO:0018208 biolink:BiologicalProcess peptidyl-proline modification The modification of peptidyl-proline. go-plus.json http://purl.obolibrary.org/obo/GO_0018208 NCBITaxon:224756 biolink:OrganismalEntity Methanomicrobia go-plus.json Methanogen Class II|'Methanomicrobia' http://purl.obolibrary.org/obo/NCBITaxon_224756 GO:0018205 biolink:BiologicalProcess peptidyl-lysine modification The modification of peptidyl-lysine. go-plus.json http://purl.obolibrary.org/obo/GO_0018205 GO:0043259 biolink:CellularComponent laminin-10 complex A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains. go-plus.json laminin-511 complex http://purl.obolibrary.org/obo/GO_0043259 GO:0018204 biolink:BiologicalProcess peptidyl-leucine modification The modification of peptidyl-leucine. go-plus.json http://purl.obolibrary.org/obo/GO_0018204 GO:0018207 biolink:BiologicalProcess peptidyl-phenylalanine modification The modification of peptidyl-phenylalanine. go-plus.json http://purl.obolibrary.org/obo/GO_0018207 GO:0018206 biolink:BiologicalProcess peptidyl-methionine modification The modification of peptidyl-methionine. go-plus.json http://purl.obolibrary.org/obo/GO_0018206 GO:0033842 biolink:MolecularActivity N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group. MetaCyc:2.4.1.244-RXN|RHEA:20493|EC:2.4.1.244 go-plus.json UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity|beta1,4-N-acetylgalactosaminyltransferase III activity|beta4GalNAc-T4|beta4GalNAc-T3|beta1,4-N-acetylgalactosaminyltransferase IV activity|beta1,4-N-acetylgalactosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0033842 UBERON:0005835 biolink:AnatomicalEntity cuneate fasciculus of spinal cord An axon tract in the spinal cord which primarily transmits information from the forelimb and trunk. It is part of the posterior column-medial lemniscus pathway. go-plus.json cuneate fasciculus|fasciculus cuneatus medullae spinalis|tract of Burdach|burdach's tract|fasciculus cuneatus|cuneate fascicle of spinal cord http://purl.obolibrary.org/obo/UBERON_0005835 GO:0018201 biolink:BiologicalProcess peptidyl-glycine modification The modification of peptidyl-glycine. go-plus.json http://purl.obolibrary.org/obo/GO_0018201 GO:0033841 biolink:MolecularActivity 6G-fructosyltransferase activity Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0). MetaCyc:2.4.1.243-RXN|EC:2.4.1.243 go-plus.json 6G-FT|fructan:fructan 6G-fructosyltransferase activity|1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity|6G-FFT|6G-fructotransferase activity http://purl.obolibrary.org/obo/GO_0033841 GO:0018200 biolink:BiologicalProcess peptidyl-glutamic acid modification The modification of peptidyl-glutamic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0018200 GO:0033840 biolink:MolecularActivity NDP-glucose-starch glucosyltransferase activity Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1. RHEA:15873|MetaCyc:2.4.1.242-RXN|EC:2.4.1.242 go-plus.json starch synthase II activity|waxy protein|GBSSI|granule-bound starch synthase activity|starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity|NDPglucose-starch glucosyltransferase activity|granule-bound starch synthase I activity|GBSS|GBSSII|NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|granule-bound starch synthase II activity http://purl.obolibrary.org/obo/GO_0033840 GO:0018203 biolink:BiologicalProcess peptidyl-isoleucine modification The modification of peptidyl-isoleucine. go-plus.json http://purl.obolibrary.org/obo/GO_0018203 GO:0018202 biolink:BiologicalProcess peptidyl-histidine modification The modification of peptidyl-histidine. go-plus.json http://purl.obolibrary.org/obo/GO_0018202 UBERON:0005832 biolink:AnatomicalEntity cuneate fasciculus An axon tract in the spinal cord and medulla which primarily transmits information from the forelimb and trunk. It is part of the dorsal column-medial lemniscus pathway. go-plus.json cuneatus tract|fasciculus cuneus|cuneate column|fasciculus cuneatus|cuneate tract|cuneate fascicle http://purl.obolibrary.org/obo/UBERON_0005832 GO:0033839 biolink:MolecularActivity flavonol-3-O-glycoside glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside. RHEA:23544|MetaCyc:2.4.1.240-RXN|EC:2.4.1.240 go-plus.json UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033839 GO:0033838 biolink:MolecularActivity flavonol-3-O-glucoside glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside. MetaCyc:2.4.1.239-RXN|EC:2.4.1.239|RHEA:18893 go-plus.json UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033838 GO:0043261 biolink:CellularComponent laminin-12 complex A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains. go-plus.json laminin-213 complex http://purl.obolibrary.org/obo/GO_0043261 GO:0033837 biolink:MolecularActivity anthocyanin 3'-O-beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside. MetaCyc:2.4.1.238-RXN|EC:2.4.1.238|RHEA:35627 go-plus.json UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity|UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity|3'GT http://purl.obolibrary.org/obo/GO_0033837 GO:0033836 biolink:MolecularActivity flavonol 7-O-beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside. MetaCyc:2.4.1.237-RXN|EC:2.4.1.237|RHEA:23164 go-plus.json UDP-glucose:flavonol 7-O-glucosyltransferase activity|UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033836 GO:0043260 biolink:CellularComponent laminin-11 complex A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains. go-plus.json laminin-521 complex http://purl.obolibrary.org/obo/GO_0043260 GO:0033835 biolink:MolecularActivity flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]. EC:2.4.1.236|RHEA:15473|MetaCyc:RXN-7759|MetaCyc:RXN-5004|MetaCyc:RXN-9699|MetaCyc:RXN-5002|MetaCyc:RXN-5001 go-plus.json UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity|1->2 UDP-rhamnosyltransferase activity|UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity http://purl.obolibrary.org/obo/GO_0033835 GO:0033834 biolink:MolecularActivity kaempferol 3-O-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside. MetaCyc:2.4.1.234-RXN|EC:2.4.1.234|RHEA:15709 go-plus.json UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity|F3GalTase activity http://purl.obolibrary.org/obo/GO_0033834 GO:0008899 biolink:MolecularActivity homoserine O-succinyltransferase activity Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA. MetaCyc:HOMSUCTRAN-RXN|EC:2.3.1.46|KEGG_REACTION:R01777|RHEA:22008 go-plus.json homoserine O-transsuccinylase activity|succinyl-CoA:L-homoserine O-succinyltransferase activity|homoserine succinyltransferase activity http://purl.obolibrary.org/obo/GO_0008899 GO:0033833 biolink:MolecularActivity hydroxymethylfurfural reductase (NADH) activity Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+. MetaCyc:RXN-10738 go-plus.json http://purl.obolibrary.org/obo/GO_0033833 GO:0008898 biolink:MolecularActivity S-adenosylmethionine-homocysteine S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine. RHEA:21820|MetaCyc:HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:L-homocysteine methyltransferase activity|L-homocysteine S-methyltransferase activity|S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity|homocysteine transmethylase activity|S-adenosylmethionine homocysteine transmethylase activity|adenosylmethionine:homocysteine methyltransferase activity|S-adenosylmethionine:homocysteine methyltransferase activity|homocysteine methyltransferase activity|adenosylmethionine transmethylase activity|S-adenosylmethionine-homocysteine transmethylase activity http://purl.obolibrary.org/obo/GO_0008898 GO:0033832 biolink:MolecularActivity alpha,alpha-trehalose phosphorylase (configuration-retaining) activity Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate. RHEA:16257|MetaCyc:RXN-4441 go-plus.json alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity|trehalose phosphorylase activity http://purl.obolibrary.org/obo/GO_0033832 UBERON:0005814 biolink:AnatomicalEntity arch of atlas A vertebral arch that is part of the first cervical vertebra go-plus.json atlas arch http://purl.obolibrary.org/obo/UBERON_0005814 GO:0008897 biolink:MolecularActivity holo-[acyl-carrier-protein] synthase activity Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. EC:2.7.8.7|Reactome:R-HSA-199202|RHEA:12068|MetaCyc:HOLO-ACP-SYNTH-RXN go-plus.json AcpS|alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|holo-ACP synthase activity|phosphopantetheinyltransferase activity|alpha-aminoadipate reductase phosphopantetheinyl transferase activity|phosphopantetheinyl transferase|CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity|CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity|acyl carrier protein synthetase activity|acyl carrier protein holoprotein (holo-ACP) synthetase activity|alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|P-pant transferase activity|holo-[peptidyl-carrier protein] synthase activity|holo-ACP synthetase activity|holo-acyl-carrier-protein synthase activity|holo-[acyl-carrier-protein] synthase activity|PPTase activity|coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity|holosynthase activity|4'-phosphopantetheinyl transferase activity|ACPS activity|L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|acyl carrier protein synthase activity|4'-phosphopantetheinyltransferase activity http://purl.obolibrary.org/obo/GO_0008897 GO:0043267 biolink:BiologicalProcess negative regulation of potassium ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json transmembrane conductance regulator activity|regulation of potassium conductance|negative regulation of potassium ion conductance|down regulation of potassium ion transport|downregulation of potassium ion transport|regulation of K+ conductance|down-regulation of potassium ion transport|negative regulation of K+ transport|inhibition of potassium ion transport|negative regulation of potassium transport http://purl.obolibrary.org/obo/GO_0043267 GO:0043266 biolink:BiologicalProcess regulation of potassium ion transport Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of K+ transport|regulation of potassium conductance|regulation of potassium transport|regulation of K+ conductance|regulation of potassium ion conductance http://purl.obolibrary.org/obo/GO_0043266 GO:0008896 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008896 GO:0043269 biolink:BiologicalProcess regulation of ion transport Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0043269 GO:0008895 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008895 GO:0008894 biolink:MolecularActivity guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate. EC:3.6.1.40|RHEA:13073|MetaCyc:PPPGPPHYDRO-RXN go-plus.json guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity|guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity|guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity|guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity|guanosine pentaphosphate phosphatase activity|guanosine pentaphosphate phosphohydrolase activity|guanosine pentaphosphatase activity|pppGpp 5'-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008894 GO:0043268 biolink:BiologicalProcess positive regulation of potassium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json positive regulation of potassium ion conductance|upregulation of potassium ion transport|positive regulation of potassium conductance|positive regulation of K+ conductance|up regulation of potassium ion transport|activation of potassium ion transport|stimulation of potassium ion transport|positive regulation of potassium transport|positive regulation of K+ transport|up-regulation of potassium ion transport http://purl.obolibrary.org/obo/GO_0043268 GO:0008893 biolink:MolecularActivity guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate. MetaCyc:PPGPPSYN-RXN|EC:3.1.7.2|RHEA:14253 go-plus.json guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity|penta-phosphate guanosine-3'-diphosphohydrolase activity|penta-phosphate guanosine-3'-pyrophosphohydrolase activity|(ppGpp)ase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity|PpGpp-3'-pyrophosphohydrolase activity|PpGpp phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008893 GO:0043263 biolink:CellularComponent cellulosome An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose. Wikipedia:Cellulosome go-plus.json scaffoldin complex http://purl.obolibrary.org/obo/GO_0043263 GO:0043262 biolink:MolecularActivity adenosine-diphosphatase activity Catalysis of the reaction: ADP + H2O = AMP + phosphate. MetaCyc:APYRASE-RXN|RHEA:61436 go-plus.json ATP-diphosphatase activity|adenosine diphosphatase activity|ATP diphosphohydrolase activity|ADPase activity|ADPase http://purl.obolibrary.org/obo/GO_0043262 GO:0008892 biolink:MolecularActivity guanine deaminase activity Catalysis of the reaction: guanine + H2O = xanthine + NH3. Reactome:R-HSA-74255|RHEA:14665|EC:3.5.4.3|MetaCyc:GUANINE-DEAMINASE-RXN go-plus.json guanase activity|guanine aminase activity|GAH activity|guanine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0008892 GO:0043265 biolink:CellularComponent ectoplasm Granule free cytoplasm, lying immediately below the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0043265 GO:0008891 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008891 GO:0043264 biolink:CellularComponent extracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. go-plus.json extracellular non-membrane-enclosed organelle http://purl.obolibrary.org/obo/GO_0043264 GO:0008890 biolink:MolecularActivity glycine C-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+). EC:2.3.1.29|RHEA:20736|KEGG_REACTION:R00371|MetaCyc:AKBLIG-RXN go-plus.json 2-amino-3-ketobutyrate coenzyme A ligase activity|2-amino-3-ketobutyrate-CoA ligase activity|glycine acetyltransferase activity|acetyl-CoA:glycine C-acetyltransferase activity|aminoacetone synthase activity|2-amino-3-ketobutyrate CoA ligase activity http://purl.obolibrary.org/obo/GO_0008890 GO:0018219 biolink:BiologicalProcess peptidyl-cysteine S-acetylation The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine. RESID:AA0056 go-plus.json http://purl.obolibrary.org/obo/GO_0018219 CHEBI:138558 biolink:ChemicalSubstance (3E,5Z)-dodecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138558 chebi_ph7_3 GO:0018216 biolink:BiologicalProcess peptidyl-arginine methylation The addition of a methyl group to an arginine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018216 GO:0018215 biolink:BiologicalProcess protein phosphopantetheinylation The modification of a protein amino acid by phosphopantetheinylation. go-plus.json protein amino acid phosphopantetheinylation http://purl.obolibrary.org/obo/GO_0018215 GO:0018218 biolink:BiologicalProcess peptidyl-cysteine phosphorylation The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine. RESID:AA0034 go-plus.json http://purl.obolibrary.org/obo/GO_0018218 GO:0018217 biolink:BiologicalProcess peptidyl-aspartic acid phosphorylation The phosphorylation of peptidyl-aspartic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0018217 GO:0018212 biolink:BiologicalProcess peptidyl-tyrosine modification The modification of peptidyl-tyrosine. go-plus.json http://purl.obolibrary.org/obo/GO_0018212 GO:0033831 biolink:MolecularActivity kojibiose phosphorylase activity Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose. RHEA:11176|MetaCyc:2.4.1.230-RXN|KEGG_REACTION:R07264|EC:2.4.1.230 go-plus.json 2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033831 GO:0033830 biolink:MolecularActivity Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline. EC:2.4.1.229|RHEA:17841 go-plus.json UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity|Skp1-HyPro GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity|UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity|UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity http://purl.obolibrary.org/obo/GO_0033830 GO:0018211 biolink:BiologicalProcess peptidyl-tryptophan modification The chemical alteration of a tryptophan residue in a peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0018211 GO:0018214 biolink:BiologicalProcess protein carboxylation The addition of a carboxy group to a protein amino acid. go-plus.json protein amino acid carboxylation http://purl.obolibrary.org/obo/GO_0018214 UBERON:0005821 biolink:AnatomicalEntity gracile fasciculus A group of axons that are from neurons involved in proprioception from the lower trunk and lower limb[GO]. The fasciculus gracilis (tract of Goll) is a bundle of axon fibres in the dorsomedial spinal cord that carries information about fine touch, vibrations, and conscious proprioception from the lower part of the body to the brain stem. It is part of the posterior column of the spinal cord, which also contains the fasciculus cuneatus, which carries the same information from the upper part of the body. This tract and its continuation in the brain stem is often referred to as the posterior column-medial lemniscus pathway. The fasciculus gracilis is wedge-shaped on transverse section and lies next the posterior median septum, its base being at the surface of the medulla spinalis, and its apex directed toward the posterior gray commissure. It increases in size from below upward, and consists of long thin fibers that are derived from the posterior nerve roots, and ascend as far as the medulla oblongata, where they end in the nucleus gracilis. The tract of Goll was named after Swiss neuroanatomist Friedrich Goll[WP]. go-plus.json gracile column|f. gracilis medullae spinalis|gracilis tract|gracile fascicle|gracile tract|fasciculus gracilis|tract of Goll http://purl.obolibrary.org/obo/UBERON_0005821 GO:0018213 biolink:BiologicalProcess peptidyl-valine modification The modification of peptidyl-valine. go-plus.json http://purl.obolibrary.org/obo/GO_0018213 GO:0018210 biolink:BiologicalProcess peptidyl-threonine modification The modification of peptidyl-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0018210 GO:0043270 biolink:BiologicalProcess positive regulation of ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json upregulation of ion transport|up regulation of ion transport|activation of ion transport|stimulation of ion transport|up-regulation of ion transport http://purl.obolibrary.org/obo/GO_0043270 GO:0033828 biolink:MolecularActivity glucosylglycerol-phosphate synthase activity Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+). KEGG_REACTION:R05328|MetaCyc:2.4.1.213-RXN|RHEA:12881|EC:2.4.1.213 go-plus.json ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|GG-phosphate synthase activity|glucosyl-glycerol-phosphate synthase activity|ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|GGPS http://purl.obolibrary.org/obo/GO_0033828 GO:0033827 biolink:MolecularActivity high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum. EC:2.4.1.197|MetaCyc:2.4.1.197-RXN go-plus.json acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0033827 GO:0033826 biolink:MolecularActivity xyloglucan 4-glucosyltransferase activity Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage. MetaCyc:2.4.1.168-RXN|EC:2.4.1.168 go-plus.json uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity|UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|xyloglucan glucosyltransferase activity|UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|xyloglucan 4beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033826 GO:0043272 biolink:BiologicalProcess ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance. go-plus.json ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance|ethylene biosynthetic process during jasmonic acid and ethylene-dependent systemic resistance|ethylene synthesis during jasmonic acid and ethylene-dependent systemic resistance|ethylene formation during jasmonic acid and ethylene-dependent systemic resistance http://purl.obolibrary.org/obo/GO_0043272 UBERON:0005808 biolink:AnatomicalEntity bone tissue of long bone A bone tissue that is part of a long bone. go-plus.json osseous tissue of long bone http://purl.obolibrary.org/obo/UBERON_0005808 GO:0008869 biolink:MolecularActivity galactonate dehydratase activity Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O. RHEA:18649|KEGG_REACTION:R03033|EC:4.2.1.6|MetaCyc:GALACTONDEHYDRAT-RXN go-plus.json D-galactonate dehydratase activity|D-galactonate hydro-lyase activity|D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-galactonate dehydrase activity http://purl.obolibrary.org/obo/GO_0008869 GO:0033825 biolink:MolecularActivity oligosaccharide 4-alpha-D-glucosyltransferase activity Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides. EC:2.4.1.161|MetaCyc:2.4.1.161-RXN go-plus.json 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity|amylase III activity http://purl.obolibrary.org/obo/GO_0033825 GO:0043271 biolink:BiologicalProcess negative regulation of ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down regulation of ion transport|downregulation of ion transport|down-regulation of ion transport|inhibition of ion transport http://purl.obolibrary.org/obo/GO_0043271 GO:0033824 biolink:MolecularActivity alternansucrase activity Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages. EC:2.4.1.140|MetaCyc:2.4.1.140-RXN go-plus.json sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity|sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033824 GO:0008868 biolink:MolecularActivity galactitol-1-phosphate 5-dehydrogenase activity Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+. RHEA:15137|MetaCyc:1.1.1.251-RXN|EC:1.1.1.251 go-plus.json galactitol-1-phosphate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008868 UBERON:0005806 biolink:AnatomicalEntity portal system In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]. go-plus.json portal venous system http://purl.obolibrary.org/obo/UBERON_0005806 GO:0008867 biolink:MolecularActivity galactarate dehydratase activity Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O. KEGG_REACTION:R05608|EC:4.2.1.42|RHEA:16005|MetaCyc:GALACTARDEHYDRA-RXN go-plus.json D-galactarate hydro-lyase activity|D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming) http://purl.obolibrary.org/obo/GO_0008867 GO:0033823 biolink:MolecularActivity procollagen glucosyltransferase activity Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen. EC:2.4.1.66|RHEA:12576|Reactome:R-HSA-1981157|MetaCyc:PROCOLLAGEN-GLUCOSYLTRANSFERASE-RXN go-plus.json galactosylhydroxylysine glucosyltransferase activity|uridine diphosphoglucose-collagen glucosyltransferase activity|UDP-glucose-collagenglucosyltransferase activity|collagen glucosyltransferase activity|UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|galactosylhydroxylysyl glucosyltransferase activity|galactosylhydroxylysine-glucosyltransferase activity|UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|collagen hydroxylysyl glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033823 UBERON:0005805 biolink:AnatomicalEntity dorsal aorta The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. go-plus.json DA|dorsal aortae|dorsal aorta root|aorta dorsalis|aortae dorsales|dorsal aortic root|dorsal aortæ http://purl.obolibrary.org/obo/UBERON_0005805 GO:0033822 biolink:MolecularActivity glucosyl-DNA beta-glucosyltransferase activity Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA. EC:2.4.1.28|MetaCyc:2.4.1.28-RXN go-plus.json T6-glucosyl-HMC-beta-glucosyl transferase activity|UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity|UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|T6-beta-glucosyl transferase activity http://purl.obolibrary.org/obo/GO_0033822 GO:0008866 biolink:MolecularActivity fructuronate reductase activity Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH. RHEA:15729|KEGG_REACTION:R02454|MetaCyc:MANNONOXIDOREDUCT-RXN|EC:1.1.1.57 go-plus.json mannonate oxidoreductase activity|D-mannonate oxidoreductase activity|mannonic dehydrogenase activity|D-mannonate:NAD oxidoreductase activity|D-mannonate dehydrogenase activity|D-mannonate:NAD+ 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008866 GO:0008865 biolink:MolecularActivity fructokinase activity Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. EC:2.7.1.4|RHEA:16125|MetaCyc:FRUCTOKINASE-RXN go-plus.json D-fructose(D-mannose)kinase activity|D-fructokinase activity|fructokinase (phosphorylating)|ATP:D-fructose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008865 GO:0033821 biolink:MolecularActivity DNA beta-glucosyltransferase activity Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA. EC:2.4.1.27|MetaCyc:2.4.1.27-RXN go-plus.json UDPglucose:DNA beta-D-glucosyltransferase activity|uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity|T4-HMC-beta-glucosyl transferase activity|UDP-glucose:DNA beta-D-glucosyltransferase activity|T4 phage beta-glucosyltransferase activity|T4-beta-glucosyl transferase activity|UDP glucose-DNA beta-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033821 GO:0008864 biolink:MolecularActivity formyltetrahydrofolate deformylase activity Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+). KEGG_REACTION:R00944|EC:3.5.1.10|RHEA:19833|MetaCyc:FORMYLTHFDEFORMYL-RXN go-plus.json formyltetrahydrofolate hydrolase activity|formyl-FH(4) hydrolase activity|10-formyltetrahydrofolate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0008864 GO:0043278 biolink:BiologicalProcess response to morphine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure. go-plus.json http://purl.obolibrary.org/obo/GO_0043278 GO:0008863 biolink:MolecularActivity formate dehydrogenase (NAD+) activity Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH. UM-BBD_reactionID:r0103|MetaCyc:FORMATEDEHYDROG-RXN|EC:1.17.1.9|RHEA:15985|MetaCyc:1.2.1.2-RXN|KEGG_REACTION:R00519 go-plus.json formate hydrogenlyase|FDH I|formic acid dehydrogenase|formate:NAD+ oxidoreductase|N-FDH|formate benzyl-viologen oxidoreductase|NAD-formate dehydrogenase|NAD-dependent formate dehydrogenase|formate-NAD oxidoreductase|formate dehydrogenase (NAD)|formic hydrogen-lyase|FDH II|NAD-linked formate dehydrogenase http://purl.obolibrary.org/obo/GO_0008863 GO:0043277 biolink:BiologicalProcess apoptotic cell clearance The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. go-plus.json apoptotic cell removal|efferocytosis|programmed cell clearance http://purl.obolibrary.org/obo/GO_0043277 GO:0008862 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008862 GO:0008861 biolink:MolecularActivity formate C-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate. RHEA:11844|EC:2.3.1.54|MetaCyc:PYRUVFORMLY-RXN go-plus.json acetyl-CoA:formate C-acetyltransferase activity|pyruvate formate:lyase activity|pyruvic formate-lyase activity|pyruvate formate-lyase activity|formate acetyltransferase activity|PFL http://purl.obolibrary.org/obo/GO_0008861 GO:0043279 biolink:BiologicalProcess response to alkaloid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. go-plus.json http://purl.obolibrary.org/obo/GO_0043279 GO:0008860 biolink:MolecularActivity ferredoxin-NAD+ reductase activity Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+. EC:1.18.1.3|RHEA:16521|MetaCyc:FERREDOXIN--NAD+-REDUCTASE-RXN go-plus.json NAD-ferredoxin reductase activity|ferredoxin-linked NAD reductase activity|ferredoxin:NAD+ oxidoreductase activity|NADH flavodoxin oxidoreductase activity|NADH-ferredoxin oxidoreductase activity|ferredoxin-nicotinamide adenine dinucleotide reductase activity|ferredoxin-NAD reductase activity|NADH2-ferredoxin oxidoreductase activity|reductase, reduced nicotinamide adenine dinucleotide-ferredoxin|NADH-ferredoxinTOL reductase (component of toluene dioxygenase)|NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)|NADH-ferredoxin reductase activity http://purl.obolibrary.org/obo/GO_0008860 GO:0043274 biolink:MolecularActivity phospholipase binding Binding to a phospholipase. go-plus.json http://purl.obolibrary.org/obo/GO_0043274 CHEBI:44278 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44278 chebi_ph7_3 GO:0043273 biolink:MolecularActivity CTPase activity Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction. go-plus.json cytidine triphosphatase activity|single-stranded DNA-dependent CTPase activity|CTPase activity, coupled http://purl.obolibrary.org/obo/GO_0043273 GO:0043276 biolink:BiologicalProcess anoikis Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix. Wikipedia:Anoikis go-plus.json suspension induced apoptosis|detachment induced cell death http://purl.obolibrary.org/obo/GO_0043276 GO:0043275 biolink:MolecularActivity obsolete glutamate carboxypeptidase II activity OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu. go-plus.json pteroylpolyglutamate hydrolase activity|glutamate carboxypeptidase II activity|membrane glutamate carboxypeptidase|NAALA dipeptidase activity|N-acetylated alpha-linked acidic dipeptidase activity|prostrate-specific membrane antigen|pteroylpoly-gamma-glutamate hydrolase activity|pteroylpolygammaglutamyl hydrolase activity|folate hydrolase activity|N-acetylated-gamma-linked-acidic dipeptidase activity|mGCP|prostate-specific membrane antigen|N-acetylated-gamma-linked-acidic dipeptidase (NAALADase)|N-acetylated-alpha-linked-amino dipeptidase activity|pteroylpolyglutamic acid hydrolase activity|pteroylpoly-gamma-glutamate carboxypeptidase activity|rat NAAG peptidase|NAALADase activity|folylpolyglutamate hydrolase activity|acetylaspartylglutamate dipeptidase activity|PSM antigen|PSMA|microsomal gamma-glutamyl carboxypeptidase http://purl.obolibrary.org/obo/GO_0043275 GO:0033829 biolink:MolecularActivity O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor. Reactome:R-HSA-5096538|MetaCyc:2.4.1.222-RXN|Reactome:R-HSA-1912355|EC:2.4.1.222 go-plus.json O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity|UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0033829 UBERON:0005813 biolink:AnatomicalEntity tubercle A round nodule, small eminence, or warty outgrowth found on bones, skin, or within the lungs in tuberculosis. They are also found on the leading edge of Humpback Whale's flippers, improving fluid flow over the flipper's surface[WP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005813 GO:0033820 biolink:MolecularActivity DNA alpha-glucosyltransferase activity Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA. EC:2.4.1.26|MetaCyc:2.4.1.26-RXN go-plus.json T6-HMC-alpha-glucosyl transferase activity|T4-HMC-alpha-glucosyl transferase activity|T2-HMC-alpha-glucosyl transferase activity|uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity|UDP-glucose:DNA alpha-D-glucosyltransferase activity|UDPglucose-DNA alpha-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033820 GO:0033817 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033817 GO:0043281 biolink:BiologicalProcess regulation of cysteine-type endopeptidase activity involved in apoptotic process Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis. go-plus.json regulation of caspase activation|regulation of caspase activity http://purl.obolibrary.org/obo/GO_0043281 GO:0033816 biolink:MolecularActivity diaminobutyrate acetyltransferase activity Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+). MetaCyc:R102-RXN|KEGG_REACTION:R06978|RHEA:16901|EC:2.3.1.178 go-plus.json acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity|diaminobutyric acid acetyltransferase activity|DAB acetyltransferase activity|2,4-diaminobutanoate acetyltransferase activity|L-2,4-diaminobutanoate acetyltransferase activity|DABA acetyltransferase activity|L-2,4-diaminobutyrate acetyltransferase activity|DABAcT|acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity|EctA http://purl.obolibrary.org/obo/GO_0033816 GO:0043280 biolink:BiologicalProcess positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process. go-plus.json up regulation of caspase activity|positive regulation of caspase activity|upregulation of caspase activity|stimulation of caspase activity|activation of caspase activity|up-regulation of caspase activity http://purl.obolibrary.org/obo/GO_0043280 GO:0033815 biolink:MolecularActivity biphenyl synthase activity Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2. MetaCyc:2.3.1.177-RXN|RHEA:22292|EC:2.3.1.177 go-plus.json malonyl-CoA:benzoyl-CoA malonyltransferase activity|BIS http://purl.obolibrary.org/obo/GO_0033815 GO:0043283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043283 GO:0033814 biolink:MolecularActivity propanoyl-CoA C-acyltransferase activity Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. RHEA:16865|MetaCyc:2.3.1.176-RXN|EC:2.3.1.176 go-plus.json 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity|PTE-2|SCPchi|peroxisomal thiolase 2 activity|sterol carrier protein-chi|sterol carrier protein-X|SCP-X http://purl.obolibrary.org/obo/GO_0033814 GO:0043282 biolink:BiologicalProcess pharyngeal muscle development The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx. go-plus.json http://purl.obolibrary.org/obo/GO_0043282 GO:0008879 biolink:MolecularActivity glucose-1-phosphate thymidylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose. MetaCyc:DTDPGLUCOSEPP-RXN|KEGG_REACTION:R02328|RHEA:15225|EC:2.7.7.24 go-plus.json glucose 1-phosphate thymidylyltransferase activity|dTDP-glucose synthase activity|dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity|thymidine diphosphoglucose pyrophosphorylase activity|dTDP-glucose pyrophosphorylase activity|dTDP-glucose diphosphorylase activity|TDP-glucose pyrophosphorylase activity|thymidine diphosphate glucose pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0008879 GO:0033813 biolink:MolecularActivity deacetylcephalosporin-C acetyltransferase activity Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA. RHEA:23860|KEGG_REACTION:R03064|MetaCyc:2.3.1.175-RXN|EC:2.3.1.175 go-plus.json cefG|deacetylcephalosporin C acetyltransferase activity|DAC-AT|acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity|acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity|acetyl coenzyme A:DAC acetyltransferase activity|acetyl-CoA:DAC acetyltransferase activity|acetyl-CoA:DAC O-acetyltransferase activity|CPC acetylhydrolase activity|DAC acetyltransferase activity http://purl.obolibrary.org/obo/GO_0033813 GO:0008878 biolink:MolecularActivity glucose-1-phosphate adenylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate. MetaCyc:GLUC1PADENYLTRANS-RXN|KEGG_REACTION:R00948|EC:2.7.7.27|RHEA:12120 go-plus.json ADGase activity|ADP-glucose pyrophosphorylase activity|ADP-glucose diphosphorylase activity|ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ADP-glucose synthetase activity|adenosine diphosphate glucose pyrophosphorylase activity|ADP glucose pyrophosphorylase activity|ADPG pyrophosphorylase activity|ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ATP:alpha-glucose-1-phosphate adenylyl transferase activity|glucose 1-phosphate adenylyltransferase activity|ADP-glucose synthase activity|adenosine diphosphoglucose pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0008878 GO:0033812 biolink:MolecularActivity 3-oxoadipyl-CoA thiolase activity Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA. EC:2.3.1.174|RHEA:19481|MetaCyc:RXN-3641 go-plus.json succinyl-CoA:acetyl-CoA C-succinyltransferase activity http://purl.obolibrary.org/obo/GO_0033812 GO:0033811 biolink:MolecularActivity flavonol-3-O-triglucoside O-coumaroyltransferase activity Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]. RHEA:22160|MetaCyc:2.3.1.173-RXN|EC:2.3.1.173 go-plus.json 4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity http://purl.obolibrary.org/obo/GO_0033811 GO:0008877 biolink:MolecularActivity glucose-1-phosphatase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate. KEGG_REACTION:R00304|MetaCyc:GLUCOSE-1-PHOSPHAT-RXN|EC:3.1.3.10|RHEA:19933 go-plus.json alpha-D-glucose-1-phosphate phosphohydrolase activity|D-glucose-1-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008877 GO:0008876 biolink:MolecularActivity quinoprotein glucose dehydrogenase activity Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol. MetaCyc:GLUCDEHYDROG-RXN|RHEA:22152|EC:1.1.5.2 go-plus.json D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity|D-glucose:ubiquinone oxidoreductase activity|glucose dehydrogenase (pyrroloquinoline-quinone) activity|glucose dehydrogenase (PQQ-dependent) activity|quinoprotein D-glucose dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008876 GO:0033810 biolink:MolecularActivity anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin. MetaCyc:2.3.1.172-RXN|EC:2.3.1.172|RHEA:21988 go-plus.json malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity|Ss5MaT1 http://purl.obolibrary.org/obo/GO_0033810 GO:0043289 biolink:BiologicalProcess apocarotenoid biosynthetic process The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid. go-plus.json apocarotenoid synthesis|apocarotenoid formation|apocarotenoid biosynthesis|apo carotenoid biosynthetic process|apocarotenoid anabolism http://purl.obolibrary.org/obo/GO_0043289 GO:0008875 biolink:MolecularActivity gluconate dehydrogenase activity Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+. go-plus.json http://purl.obolibrary.org/obo/GO_0008875 GO:0043288 biolink:BiologicalProcess apocarotenoid metabolic process The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid. go-plus.json apo carotenoid metabolic process|apocarotenoid metabolism http://purl.obolibrary.org/obo/GO_0043288 GO:0008874 biolink:MolecularActivity gluconate 5-dehydrogenase activity Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+. EC:1.1.1.69|MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN go-plus.json 5-ketogluconate reductase activity|5-ketogluconate 5-reductase activity|5-keto-D-gluconate reductase|D-gluconate:NAD(P)+ 5-oxidoreductase|5-keto-D-gluconate 5-reductase activity http://purl.obolibrary.org/obo/GO_0008874 GO:0008873 biolink:MolecularActivity gluconate 2-dehydrogenase activity Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+. MetaCyc:1.1.1.215-RXN|RHEA:16653|EC:1.1.1.215 go-plus.json 2-keto-D-gluconate reductase activity|D-gluconate:NADP+ oxidoreductase activity|2-ketogluconate reductase activity http://purl.obolibrary.org/obo/GO_0008873 GO:0008872 biolink:MolecularActivity glucarate dehydratase activity Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O. EC:4.2.1.40|RHEA:14573|MetaCyc:GLUCARDEHYDRA-RXN go-plus.json D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)|D-glucarate dehydratase activity|D-glucarate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0008872 GO:0008871 biolink:MolecularActivity aminoglycoside 2''-nucleotidyltransferase activity Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside. MetaCyc:2.7.7.46-RXN|EC:2.7.7.46 go-plus.json gentamicin 2''- adenylyltransferase activity|gentamicin 2''-nucleotidyltransferase activity|2''-aminoglycoside nucleotidyltransferase activity|NTP:gentamicin 2''-nucleotidyltransferase activity|gentamycin 2''-nucleotidyltransferase activity http://purl.obolibrary.org/obo/GO_0008871 GO:0043285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043285 GO:0008870 biolink:MolecularActivity galactoside O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside. EC:2.3.1.18|RHEA:15713|MetaCyc:GALACTOACETYLTRAN-RXN go-plus.json galactoside acetyltransferase activity|thiogalactoside acetyltransferase activity|thiogalactoside transacetylase activity|acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0008870 GO:0043284 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043284 GO:0043287 biolink:MolecularActivity poly(3-hydroxyalkanoate) binding Binding to a poly(3-hydroxyalkanoate), a polyester of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. go-plus.json PHA binding http://purl.obolibrary.org/obo/GO_0043287 GO:0033819 biolink:MolecularActivity lipoyl(octanoyl) transferase activity Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein. MetaCyc:RXN0-947|Reactome:R-HSA-6793590|EC:2.3.1.181 go-plus.json lipoyl (octanoyl)-acyl carrier protein:protein transferase activity|octanoyl-acyl carrier protein-protein N-octanoyltransferase activity|lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity|octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity|lipoate/octanoate transferase activity|LipB|octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity http://purl.obolibrary.org/obo/GO_0033819 GO:0033818 biolink:MolecularActivity beta-ketoacyl-acyl-carrier-protein synthase III activity Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2. RHEA:12080|MetaCyc:2.3.1.180-RXN|EC:2.3.1.180 go-plus.json acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity|beta-ketoacyl (acyl carrier protein) synthase III activity|beta-ketoacyl-ACP synthase III activity|KASIII|3-ketoacyl-acyl carrier protein synthase III activity|KAS III|beta-ketoacyl-acyl carrier protein synthase III activity|3-oxoacyl:ACP synthase III activity|FabH http://purl.obolibrary.org/obo/GO_0033818 GO:0043286 biolink:BiologicalProcess regulation of poly(3-hydroxyalkanoate) biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. go-plus.json regulation of poly(3-hydroxyalkanoate) formation|regulation of PHA|regulation of poly(3-hydroxyalkanoate) biosynthesis|regulation of poly(3-hydroxyalkanoate) anabolism|regulation of poly(3-hydroxyalkanoate) synthesis http://purl.obolibrary.org/obo/GO_0043286 CHEBI:138538 biolink:ChemicalSubstance O-{S-[3-oxo-(11Z)-octadecenoyl]pantetheine-4'-phosphoryl}-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138538 chebi_ph7_3 UBERON:0005800 biolink:AnatomicalEntity section of aorta Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle. go-plus.json portion of aorta|aortic segment|segment of aorta|aortic section http://purl.obolibrary.org/obo/UBERON_0005800 CHEBI:138532 biolink:ChemicalSubstance lysophosphatidylethanolamine 17:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138532 CHEBI:83859 biolink:ChemicalSubstance dalnigrein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83859 chebi_ph7_3 CHEBI:83856 biolink:ChemicalSubstance dalpatein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83856 chebi_ph7_3 CHEBI:83866 biolink:ChemicalSubstance N-acyl-D-galactosylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83866 chebi_ph7_3 CHEBI:83865 biolink:ChemicalSubstance androst-5-ene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_83865 chebi_ph7_3 CHEBI:83864 biolink:ChemicalSubstance (R)-lipoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_83864 CHEBI:83863 biolink:ChemicalSubstance (25S)-3-ketocholest-4-en-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_83863 chebi_ph7_3 CHEBI:83862 biolink:ChemicalSubstance (25R)-3-ketocholest-4-en-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_83862 chebi_ph7_3 CHEBI:83861 biolink:ChemicalSubstance (25R)-26-hydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_83861 chebi_ph7_3 CHEBI:83860 biolink:ChemicalSubstance (25S)-26-hydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_83860 chebi_ph7_3 CHEBI:246422 biolink:ChemicalSubstance dUMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_246422 chebi_ph7_3 CHEBI:83876 biolink:ChemicalSubstance cationic sphingoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83876 CHEBI:83875 biolink:ChemicalSubstance N-acyl-(3-O-sulfo-D-galactosyl)sphingosine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83875 chebi_ph7_3 NCBITaxon:126287 biolink:OrganismalEntity Didelphinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_126287 GO:0018292 biolink:BiologicalProcess molybdenum incorporation via L-cysteinyl molybdopterin The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin. RESID:AA0142 go-plus.json http://purl.obolibrary.org/obo/GO_0018292 GO:0018291 biolink:BiologicalProcess molybdenum incorporation into iron-sulfur cluster The incorporation of molybdenum into an iron-sulfur cluster. go-plus.json molybdenum incorporation into iron-sulphur cluster http://purl.obolibrary.org/obo/GO_0018291 GO:0018294 biolink:BiologicalProcess protein-FAD linkage via S-(8alpha-FAD)-L-cysteine The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine. RESID:AA0143 go-plus.json http://purl.obolibrary.org/obo/GO_0018294 GO:0018293 biolink:BiologicalProcess protein-FAD linkage The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD). go-plus.json http://purl.obolibrary.org/obo/GO_0018293 GO:0018290 biolink:BiologicalProcess iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase. RESID:AA0141 go-plus.json iron and molybdenum incorporation into iron-molybdenum-sulphur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulphide http://purl.obolibrary.org/obo/GO_0018290 CHEBI:83898 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alaninate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83898 chebi_ph7_3 NCBITaxon:200783 biolink:OrganismalEntity Aquificae go-plus.json Aquificae|Aquificaeota http://purl.obolibrary.org/obo/NCBITaxon_200783 GO:0018289 biolink:BiologicalProcess molybdenum incorporation into metallo-sulfur cluster The incorporation of molybdenum into a metallo-sulfur cluster. go-plus.json molybdenum incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0018289 GO:0018288 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide. RESID:AA0140 go-plus.json iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl tetrairon tetrasulphide http://purl.obolibrary.org/obo/GO_0018288 GO:0018285 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide. RESID:AA0137 go-plus.json iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl diiron disulphide http://purl.obolibrary.org/obo/GO_0018285 GO:0018284 biolink:BiologicalProcess iron incorporation into protein via tetrakis-L-cysteinyl iron The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein). RESID:AA0136 go-plus.json http://purl.obolibrary.org/obo/GO_0018284 GO:0018287 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide. RESID:AA0139 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron tetrasulphide http://purl.obolibrary.org/obo/GO_0018287 GO:0018286 biolink:BiologicalProcess obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form. go-plus.json iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide|iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron trisulphide http://purl.obolibrary.org/obo/GO_0018286 GO:0018299 biolink:BiologicalProcess iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide. RESID:AA0225 go-plus.json iron incorporation into the Rieske iron-sulphur cluster via bis-L-cysteinyl bis-L-histidino diiron disulphide http://purl.obolibrary.org/obo/GO_0018299 GO:0018296 biolink:BiologicalProcess protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine. RESID:AA0145 go-plus.json http://purl.obolibrary.org/obo/GO_0018296 GO:0018295 biolink:BiologicalProcess protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine. RESID:AA0144 go-plus.json http://purl.obolibrary.org/obo/GO_0018295 GO:0018298 biolink:BiologicalProcess protein-chromophore linkage The covalent or noncovalent attachment of a chromophore to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018298 GO:0018297 biolink:BiologicalProcess protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine. RESID:AA0221 go-plus.json http://purl.obolibrary.org/obo/GO_0018297 GO:0018270 biolink:BiologicalProcess GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0163 go-plus.json GPI anchor anabolism via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-alanyl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0018270 GO:0018272 biolink:BiologicalProcess protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine. RESID:AA0119 go-plus.json http://purl.obolibrary.org/obo/GO_0018272 GO:0018271 biolink:MolecularActivity biotin-protein ligase activity Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein. EC:6.3.4.-|MetaCyc:BIOTINLIG-RXN|Reactome:R-HSA-9035987|Reactome:R-HSA-9035990|Reactome:R-HSA-2993814|Reactome:R-HSA-9035988|Reactome:R-HSA-2993447|Reactome:R-HSA-2993799|Reactome:R-HSA-4167511|Reactome:R-HSA-2993802|Reactome:R-HSA-3323184 go-plus.json biotin-apoprotein ligase activity http://purl.obolibrary.org/obo/GO_0018271 GO:0018267 biolink:BiologicalProcess GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0160 go-plus.json GPI anchor formation via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-cysteinyl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0018267 GO:0018266 biolink:BiologicalProcess GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0159 go-plus.json GPI anchor anabolism via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-aspartyl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0018266 GO:0018269 biolink:BiologicalProcess GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0162 go-plus.json GPI anchor anabolism via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-seryl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0018269 GO:0018268 biolink:BiologicalProcess GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0161 go-plus.json GPI anchor anabolism via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-glycyl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0018268 GO:0018263 biolink:BiologicalProcess isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine. RESID:AA0216 go-plus.json http://purl.obolibrary.org/obo/GO_0018263 GO:0018262 biolink:BiologicalProcess isopeptide cross-linking The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon. go-plus.json http://purl.obolibrary.org/obo/GO_0018262 GO:0018265 biolink:BiologicalProcess GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0158 go-plus.json GPI anchor formation via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-asparaginyl-glycosylphosphatidylinositolethanolamine http://purl.obolibrary.org/obo/GO_0018265 GO:0018264 biolink:BiologicalProcess isopeptide cross-linking via N-(L-isoaspartyl)-glycine The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine. RESID:AA0126 go-plus.json http://purl.obolibrary.org/obo/GO_0018264 GO:0018281 biolink:BiologicalProcess GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein. RESID:AA0166 go-plus.json GSI anchor formation via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor synthesis via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor anabolism via N-seryl-glycosylsphingolipidinositolethanolamine http://purl.obolibrary.org/obo/GO_0018281 GO:0018280 biolink:BiologicalProcess protein S-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine. go-plus.json protein amino acid S-linked glycosylation http://purl.obolibrary.org/obo/GO_0018280 GO:0018283 biolink:BiologicalProcess iron incorporation into metallo-sulfur cluster The incorporation of iron into a metallo-sulfur cluster. go-plus.json iron incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0018283 GO:0018282 biolink:BiologicalProcess metal incorporation into metallo-sulfur cluster The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide. go-plus.json metal incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0018282 GO:0033899 biolink:MolecularActivity ribonuclease U2 activity Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates. MetaCyc:3.1.27.4-RXN|EC:4.6.1.20 go-plus.json ribonuclease (purine) activity|pleospora RNase activity|purine-specific ribonuclease activity|trichoderma koningi RNase III activity|purine specific endoribonuclease activity|ribonuclease U2 activity|RNase U2 activity|purine-specific RNase activity http://purl.obolibrary.org/obo/GO_0033899 GO:0033898 biolink:MolecularActivity Bacillus subtilis ribonuclease activity Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides. MetaCyc:3.1.27.2-RXN|EC:4.6.1.22 go-plus.json ribonucleate nucleotido-2'-transferase (cyclizing) activity|proteus mirabilis RNase activity http://purl.obolibrary.org/obo/GO_0033898 GO:0043201 biolink:BiologicalProcess response to leucine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0043201 GO:0043200 biolink:BiologicalProcess response to amino acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. go-plus.json response to amino acid stimulus http://purl.obolibrary.org/obo/GO_0043200 GO:0043203 biolink:CellularComponent axon hillock Portion of the neuronal cell soma from which the axon originates. NIF_Subcellular:sao627227260|Wikipedia:Axon_hillock go-plus.json http://purl.obolibrary.org/obo/GO_0043203 GO:0043202 biolink:CellularComponent lysosomal lumen The volume enclosed within the lysosomal membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0043202 GO:0043209 biolink:CellularComponent myelin sheath An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. Wikipedia:Myelin|FMA:62983|NIF_Subcellular:sao593830697 go-plus.json astrocyte sheath|Schwann cell myelin sheath|oligodendrocyte myelin sheath http://purl.obolibrary.org/obo/GO_0043209 GO:0043208 biolink:MolecularActivity glycosphingolipid binding Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_0043208 GO:0043205 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043205 GO:0043204 biolink:CellularComponent perikaryon The portion of the cell soma (neuronal cell body) that excludes the nucleus. go-plus.json cell soma cytoplasm http://purl.obolibrary.org/obo/GO_0043204 GO:0043207 biolink:BiologicalProcess response to external biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. go-plus.json http://purl.obolibrary.org/obo/GO_0043207 GO:0043206 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043206 GO:0033897 biolink:MolecularActivity ribonuclease T2 activity Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. EC:4.6.1.19|MetaCyc:3.1.27.1-RXN go-plus.json ribonuclease II activity|RNase T2 activity|ribonucleate nucleotido-2'-transferase (cyclizing) activity|ribonuclease M activity|RNase Ms activity|acid RNase activity|base-non-specific ribonuclease activity|RNase II activity|Escherichia coli ribonuclease I' ribonuclease PP2 activity|nonspecific RNase activity|ribonuclease (non-base specific) activity|ribonnuclease (non-base specific) activity|nonbase-specific RNase activity|ribonuclease PP3 activity|RNAase CL activity|ribonuclease U4 activity|non-base specific ribonuclease activity|ribonucleate 3'-oligonucleotide hydrolase activity|ribonuclease N2 activity|acid ribonuclease activity|RNase (non-base specific) activity|Escherichia coli ribonuclease II activity|RNase M activity http://purl.obolibrary.org/obo/GO_0033897 GO:0018278 biolink:BiologicalProcess N-terminal peptidyl-threonine deamination The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid. RESID:AA0129 go-plus.json http://purl.obolibrary.org/obo/GO_0018278 GO:0018277 biolink:BiologicalProcess protein deamination The removal of an amino group from a protein amino acid. go-plus.json protein amino acid deamination http://purl.obolibrary.org/obo/GO_0018277 GO:0033896 biolink:MolecularActivity ribonuclease IX activity Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups. MetaCyc:3.1.26.10-RXN|EC:3.1.26.10 go-plus.json poly(U)- and poly(C)-specific endoribonuclease activity http://purl.obolibrary.org/obo/GO_0033896 GO:0033895 biolink:MolecularActivity ribonuclease [poly-(U)-specific] activity Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups. EC:3.1.26.9 go-plus.json ribonuclease (uracil-specific) activity|uracil-specific endoribonuclease activity|uracil-specific RNase activity http://purl.obolibrary.org/obo/GO_0033895 GO:0033894 biolink:MolecularActivity ribonuclease P4 activity Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor. EC:3.1.26.7|MetaCyc:3.1.26.7-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0033894 GO:0018279 biolink:BiologicalProcess protein N-linked glycosylation via asparagine The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. go-plus.json protein amino acid N-linked glycosylation via asparagine http://purl.obolibrary.org/obo/GO_0018279 GO:0033893 biolink:MolecularActivity ribonuclease IV activity Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups. EC:3.1.26.6|MetaCyc:3.1.26.6-RXN go-plus.json endoribonuclease IV activity http://purl.obolibrary.org/obo/GO_0033893 GO:0018274 biolink:BiologicalProcess peptide cross-linking via L-lysinoalanine The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link. RESID:AA0123 go-plus.json http://purl.obolibrary.org/obo/GO_0018274 GO:0018273 biolink:BiologicalProcess protein-chromophore linkage via peptidyl-N6-retinal-L-lysine The modification of peptidyl-lysine to form N6-retinal-L-lysine. RESID:AA0120 go-plus.json http://purl.obolibrary.org/obo/GO_0018273 GO:0033892 biolink:MolecularActivity deoxyribonuclease (pyrimidine dimer) activity Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate. EC:3.1.25.1|MetaCyc:3.1.25.1-RXN go-plus.json T4 endonuclease V activity|bacteriophage T4 endodeoxyribonuclease V activity|endodeoxyribonuclease (pyrimidine dimer) activity http://purl.obolibrary.org/obo/GO_0033892 GO:0018276 biolink:BiologicalProcess isopeptide cross-linking via N6-glycyl-L-lysine The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination. RESID:AA0125 go-plus.json http://purl.obolibrary.org/obo/GO_0018276 GO:0033891 biolink:MolecularActivity CC-preferring endodeoxyribonuclease activity Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC. EC:3.1.21.6|MetaCyc:3.1.21.6-RXN go-plus.json 5'-CC-3'-preferring endodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic endonuclease activity|Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0033891 GO:0033890 biolink:MolecularActivity ribonuclease D activity Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides. EC:3.1.13.5|MetaCyc:3.1.13.5-RXN go-plus.json RNase D activity http://purl.obolibrary.org/obo/GO_0033890 GO:0018275 biolink:BiologicalProcess N-terminal peptidyl-cysteine acetylation The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine. RESID:AA0043 go-plus.json peptidyl-cysteine N-acetylation http://purl.obolibrary.org/obo/GO_0018275 CHEBI:58819 biolink:ChemicalSubstance (R,R)-chrysanthemyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58819 chebi_ph7_3 CHEBI:58818 biolink:ChemicalSubstance (1R,2S,5S,6S)-2-(3-carboxylatopropanoyl)-5-[(1-carboxylatovinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58818 chebi_ph7_3 CHEBI:58817 biolink:ChemicalSubstance 2-(3-methylthiopropyl)malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58817 chebi_ph7_3 CHEBI:58816 biolink:ChemicalSubstance 2-(2-methylthioethyl)malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58816 chebi_ph7_3 CHEBI:58815 biolink:ChemicalSubstance 5-methylthio-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58815 chebi_ph7_3 CHEBI:34848 biolink:ChemicalSubstance mevastatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_34848 chebi_ph7_3 CHEBI:58813 biolink:ChemicalSubstance leachianone G(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58813 CHEBI:58812 biolink:ChemicalSubstance sophoraflavanone B(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58812 CHEBI:19203 biolink:ChemicalSubstance 1H-pyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_19203 chebi_ph7_3 CHEBI:58811 biolink:ChemicalSubstance phenylglyoxylyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58811 chebi_ph7_3 CHEBI:58810 biolink:ChemicalSubstance deoxycholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58810 chebi_ph7_3 CHEBI:58809 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58809 chebi_ph7_3 CHEBI:58808 biolink:ChemicalSubstance 5beta-scymnol sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58808 chebi_ph7_3 CHEBI:58807 biolink:ChemicalSubstance ascopyrone P(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58807 CHEBI:58806 biolink:ChemicalSubstance ascopyrone M(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58806 CHEBI:58805 biolink:ChemicalSubstance c-di-GMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58805 chebi_ph7_3 CHEBI:58804 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58804 chebi_ph7_3 CHEBI:58803 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58803 chebi_ph7_3 CHEBI:995 biolink:ChemicalSubstance cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_995 CHEBI:994 biolink:ChemicalSubstance cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_994 CHEBI:58802 biolink:ChemicalSubstance 5-amino-2-oxopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58802 chebi_ph7_3 CHEBI:58801 biolink:ChemicalSubstance 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58801 chebi_ph7_3 CHEBI:58800 biolink:ChemicalSubstance 4-(L-gamma-glutamylamino)butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58800 chebi_ph7_3 UBERON:0015251 biolink:AnatomicalEntity modified sebaceous gland go-plus.json http://purl.obolibrary.org/obo/UBERON_0015251 NCBITaxon:70863 biolink:OrganismalEntity Shewanella oneidensis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_70863 UBERON:0015249 biolink:AnatomicalEntity digit skin A zone of skin that is part of a digit [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015249 CHEBI:19218 biolink:ChemicalSubstance 2',3'-cyclic pyrimidine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_19218 CHEBI:19217 biolink:ChemicalSubstance 2',3'-cyclic purine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_19217 CHEBI:83819 biolink:ChemicalSubstance (25S)-3-oxocholest-4-en-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83819 chebi_ph7_3 CHEBI:83818 biolink:ChemicalSubstance morphinane-like compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_83818 CHEBI:83813 biolink:ChemicalSubstance proteinogenic amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83813 CHEBI:83812 biolink:ChemicalSubstance non-proteinogenic amino acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83812 CHEBI:83811 biolink:ChemicalSubstance proteinogenic amino acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83811 CHEBI:10836 biolink:ChemicalSubstance 2',3,4,4',6'-pentahydroxychalcone go-plus.json http://purl.obolibrary.org/obo/CHEBI_10836 CHEBI:83828 biolink:ChemicalSubstance DNA polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83828 chebi_ph7_3 CHEBI:83824 biolink:ChemicalSubstance L-cysteine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83824 CHEBI:83822 biolink:ChemicalSubstance non-proteinogenic L-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83822 CHEBI:83821 biolink:ChemicalSubstance amino acid derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_83821 CHEBI:83820 biolink:ChemicalSubstance non-proteinogenic amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83820 CHEBI:83836 biolink:ChemicalSubstance UDP-beta-L-rhamnose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83836 chebi_ph7_3 CHEBI:83834 biolink:ChemicalSubstance peptidylproline (omega=180) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83834 chebi_ph7_3 CHEBI:83833 biolink:ChemicalSubstance peptidylproline (omega=0) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83833 chebi_ph7_3 UBERON:0015281 biolink:AnatomicalEntity pancreas right lobe A pancreatic lobule that is in_the_right_side_of a exocrine pancreas. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015281 UBERON:0015280 biolink:AnatomicalEntity pancreas left lobe A pancreatic lobule that is in_the_left_side_of a exocrine pancreas. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015280 GO:0033806 biolink:MolecularActivity fluorothreonine transaldolase activity Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine. RHEA:11748|EC:2.2.1.8 go-plus.json fluoroacetaldehyde:L-threonine aldehydetransferase activity http://purl.obolibrary.org/obo/GO_0033806 GO:0043171 biolink:BiologicalProcess peptide catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. go-plus.json peptide breakdown|peptide catabolism|peptide degradation http://purl.obolibrary.org/obo/GO_0043171 GO:0043170 biolink:BiologicalProcess macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. go-plus.json multicellular organismal macromolecule metabolic process|biopolymer metabolic process|organismal macromolecule metabolism|macromolecule metabolism http://purl.obolibrary.org/obo/GO_0043170 goslim_pir GO:0008849 biolink:MolecularActivity enterochelin esterase activity Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+. MetaCyc:RXN0-1661|RHEA:28018 go-plus.json enterobactin esterase activity http://purl.obolibrary.org/obo/GO_0008849 GO:0033805 biolink:MolecularActivity obsolete sarcosine/dimethylglycine N-methyltransferase activity OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine, and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine. go-plus.json SDMT|sarcosine dimethylglycine methyltransferase activity|sarcosine dimethylglycine N-methyltransferase activity|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity|sarcosine/dimethylglycine N-methyltransferase activity|ApDMT http://purl.obolibrary.org/obo/GO_0033805 GO:0033804 biolink:MolecularActivity obsolete glycine/sarcosine N-methyltransferase activity OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine. go-plus.json glycine sarcosine N-methyltransferase activity|GSMT|GMT|S-adenosyl-L-methionine:sarcosine N-methyltransferase activity|glycine-sarcosine methyltransferase activity|ApGSMT|glycine/sarcosine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0033804 GO:0043173 biolink:BiologicalProcess nucleotide salvage Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis. Wikipedia:Nucleotide_salvage go-plus.json http://purl.obolibrary.org/obo/GO_0043173 GO:0008848 biolink:MolecularActivity obsolete enterobactin synthetase OBSOLETE. (Was not defined before being made obsolete). go-plus.json enterochelin synthetase activity|nonribosomal peptide synthetase|enterobactin synthetase http://purl.obolibrary.org/obo/GO_0008848 GO:0033803 biolink:MolecularActivity kaempferol 4'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide. EC:2.1.1.155|KEGG_REACTION:R06807|RHEA:15105|MetaCyc:2.1.1.155-RXN go-plus.json F 4'-OMT|S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity|S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0033803 GO:0008847 biolink:MolecularActivity Enterobacter ribonuclease activity Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. MetaCyc:3.1.27.6-RXN|EC:4.6.1.21 go-plus.json Enterobacter RNase activity|enterobacter ribonuclease activity http://purl.obolibrary.org/obo/GO_0008847 GO:0043172 biolink:BiologicalProcess obsolete ferredoxin biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each. go-plus.json ferredoxin anabolism|ferredoxin biosynthesis|ferredoxin synthesis|ferredoxin formation http://purl.obolibrary.org/obo/GO_0043172 GO:0008846 biolink:MolecularActivity obsolete endopeptidase La activity OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP. go-plus.json PIM1 proteinase activity|gene lon protease activity|PIM1 protease activity|ATP-dependent serine proteinase activity|gene lon proteins|lon proteinase|endopeptidase La activity|Escherichia coli proteinase La|proteinase La|Escherichia coli serine proteinase La|protease La|serine protease La|ATP-dependent protease La activity|ATP-dependent lon proteinase http://purl.obolibrary.org/obo/GO_0008846 GO:0033802 biolink:MolecularActivity isoliquiritigenin 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+). EC:2.1.1.154|MetaCyc:RXN-3501|RHEA:21608|KEGG_REACTION:R07242 go-plus.json CHMT|chalcone OMT|S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0033802 GO:0008845 biolink:MolecularActivity obsolete endonuclease VIII activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json endonuclease VIII activity http://purl.obolibrary.org/obo/GO_0008845 GO:0033801 biolink:MolecularActivity vitexin 2''-O-rhamnoside 7-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside. EC:2.1.1.153|MetaCyc:RXN-4981|RHEA:11432 go-plus.json S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0033801 GO:0033800 biolink:MolecularActivity isoflavone 7-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone. EC:2.1.1.150|MetaCyc:RXN-6241|RHEA:17933 go-plus.json S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0033800 GO:0008844 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008844 GO:0008843 biolink:MolecularActivity endochitinase activity Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain. go-plus.json http://purl.obolibrary.org/obo/GO_0008843 GO:0008842 biolink:MolecularActivity diphosphate-purine nucleoside kinase activity Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide. MetaCyc:2.7.1.143-RXN|EC:2.7.1.143 go-plus.json diphosphate:purine nucleoside phosphotransferase activity|pyrophosphate-purine nucleoside kinase activity|pyrophosphate-dependent nucleoside kinase activity|diphosphate-dependent nucleoside kinase activity http://purl.obolibrary.org/obo/GO_0008842 GO:0043179 biolink:BiologicalProcess rhythmic excitation Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit. go-plus.json http://purl.obolibrary.org/obo/GO_0043179 GO:0043178 biolink:MolecularActivity alcohol binding Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0043178 goslim_pir GO:0008841 biolink:MolecularActivity dihydrofolate synthase activity Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate. MetaCyc:DIHYDROFOLATESYNTH-RXN|EC:6.3.2.12|RHEA:23584 go-plus.json H(2)-folate synthetase activity|dihydrofolate synthetase-folylpolyglutamate synthetase activity|folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity|dihydrofolate synthetase activity|7,8-dihydropteroate:L-glutamate ligase (ADP-forming)|FHFS activity|DHFS activity|7,8-dihydropteroate:L-glutamate ligase (ADP) activity|FHFS/FPGS activity|dihydropteroate:L-glutamate ligase (ADP-forming) activity|H2-folate synthetase activity|7,8-dihydrofolate synthetase activity http://purl.obolibrary.org/obo/GO_0008841 GO:0008840 biolink:MolecularActivity 4-hydroxy-tetrahydrodipicolinate synthase activity Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O. RHEA:14845|EC:4.3.3.7|KEGG_REACTION:R02292|MetaCyc:DIHYDRODIPICSYN-RXN go-plus.json L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)|L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]|dihydrodipicolinate synthase activity|DHDPS activity|dihydrodipicolinic acid synthase activity|dihydrodipicolinate synthetase activity|dihydropicolinate synthetase activity http://purl.obolibrary.org/obo/GO_0008840 GO:0043175 biolink:MolecularActivity RNA polymerase core enzyme binding Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0043175 GO:0033809 biolink:MolecularActivity anthocyanin 6''-O-malonyltransferase activity Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside). MetaCyc:2.3.1.171-RXN|EC:2.3.1.171|RHEA:16025 go-plus.json 3MaT|malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|Dv3MaT http://purl.obolibrary.org/obo/GO_0033809 GO:0043174 biolink:BiologicalProcess nucleoside salvage Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043174 GO:0033808 biolink:MolecularActivity 6'-deoxychalcone synthase activity Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O. EC:2.3.1.170|MetaCyc:RXN-3142|RHEA:10584 go-plus.json malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity http://purl.obolibrary.org/obo/GO_0033808 GO:0043177 biolink:MolecularActivity organic acid binding Binding to an organic acid, any acidic compound containing carbon in covalent linkage. go-plus.json http://purl.obolibrary.org/obo/GO_0043177 CHEBI:904 biolink:ChemicalSubstance 2,4-diaminopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_904 GO:0033807 biolink:MolecularActivity icosanoyl-CoA synthase activity Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+. MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|EC:2.3.1.119 go-plus.json acyl-CoA elongase activity|stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity|stearoyl-CoA elongase activity|C18-CoA elongase activity http://purl.obolibrary.org/obo/GO_0033807 GO:0043176 biolink:MolecularActivity amine binding Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group. go-plus.json http://purl.obolibrary.org/obo/GO_0043176 goslim_pir CHEBI:138625 biolink:ChemicalSubstance (+)-jasmonic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138625 chebi_ph7_3 CHEBI:58893 biolink:ChemicalSubstance precorrin-1(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58893 chebi_ph7_3 CHEBI:58892 biolink:ChemicalSubstance 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58892 chebi_ph7_3 UBERON:0005870 biolink:AnatomicalEntity olfactory pit An indentation of the olfactory placode which ends when the pits hollows out to form the nasopharynx[GO]. go-plus.json nasal pit http://purl.obolibrary.org/obo/UBERON_0005870 CHEBI:58891 biolink:ChemicalSubstance 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58891 chebi_ph7_3 CHEBI:138623 biolink:ChemicalSubstance O-[S-(pyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138623 chebi_ph7_3 CHEBI:58890 biolink:ChemicalSubstance 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58890 chebi_ph7_3 CHEBI:138622 biolink:ChemicalSubstance O-(S-L-prolylpantetheine-4'-phosphoryl)serine zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138622 chebi_ph7_3 CHEBI:138628 biolink:ChemicalSubstance 2-hydroxybutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138628 chebi_ph7_3 CHEBI:138627 biolink:ChemicalSubstance N-[(3R)-jasmonyl]-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138627 chebi_ph7_3 CHEBI:138626 biolink:ChemicalSubstance N-[(3R)-12-hydroxyjasmonyl]-L-isoleucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138626 chebi_ph7_3 UBERON:0005879 biolink:AnatomicalEntity pharyngeal cleft An external pocketing of pharyngeal ectoderm that contacts a region of endoderm (a pharyngeal pouch) and interdigitates in the anterior and posterior directions by the pharyngeal arches. go-plus.json pharyngeal groove|branchial groove|pharyngeal groove ectoderm|Kiemenspalten|sulcus pharyngei|pharyngeal ectodermal cleft|pharyngeal slit|branchial cleft|gill cleft http://purl.obolibrary.org/obo/UBERON_0005879 CHEBI:58899 biolink:ChemicalSubstance alpha-D-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58899 chebi_ph7_3 CHEBI:58898 biolink:ChemicalSubstance 2-azaniumyl-4,5-dihydroxy-6-oxo-7-(phosphonatooxy)heptanoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58898 chebi_ph7_3 UBERON:0005876 biolink:AnatomicalEntity undifferentiated genital tubercle the embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin go-plus.json phallic tubercle|genital tubercle|tuberculum phallicum|tuberculum genitale|undifferentiated genital tubercle http://purl.obolibrary.org/obo/UBERON_0005876 CHEBI:58897 biolink:ChemicalSubstance 1,4-dihydroxy-2-naphthoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58897 chebi_ph7_3 UBERON:0005875 biolink:AnatomicalEntity 4th arch pharyngeal cleft A groove that is situated between the 4th and 5th pharyngeal arch. go-plus.json 4th pharyngeal cleft|branchial groove of 4th arch|4th branchial cleft|4th pharyngeal groove|4th arch branchial groove|4th pharyngeal groove ectoderm|4th arch pharyngeal groove ectoderm http://purl.obolibrary.org/obo/UBERON_0005875 CHEBI:138621 biolink:ChemicalSubstance [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138621 chebi_ph7_3 UBERON:0005874 biolink:AnatomicalEntity 3rd arch pharyngeal cleft A groove that is situated between the 3rd and 4th pharyngeal arch. go-plus.json 3rd pharyngeal cleft|branchial groove of 3rd arch|3rd pharyngeal groove ectoderm|3rd branchial cleft|3rd pharyngeal groove|3rd arch branchial groove|3rd arch groove ectoderm http://purl.obolibrary.org/obo/UBERON_0005874 CHEBI:58896 biolink:ChemicalSubstance 2-hydroxy carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58896 chebi_ph7_3 CHEBI:138620 biolink:ChemicalSubstance O-[S-(D-alanyl)pantetheine-4'-phosphoryl]-L-serine zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138620 chebi_ph7_3 CHEBI:58895 biolink:ChemicalSubstance 2-carboxylato-4-methyl-5-[(2-phosphonatooxy)ethylidene]-2,5-dihydrothiazole(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58895 chebi_ph7_3 UBERON:0005873 biolink:AnatomicalEntity 2nd arch pharyngeal cleft A groove that is situated between the 2nd and 3rd pharyngeal arch. go-plus.json 2nd pharyngeal cleft|branchial groove of 2nd arch|2nd branchial cleft|2nd pharyngeal groove|2nd arch branchial groove|2nd pharyngeal groove ectoderm|2nd arch groove ectoderm http://purl.obolibrary.org/obo/UBERON_0005873 CHEBI:58894 biolink:ChemicalSubstance cob(II)yrinate(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58894 chebi_ph7_3 UBERON:0005872 biolink:AnatomicalEntity 1st arch pharyngeal cleft A groove that is situated between the 1st and 2nd pharyngeal arch. go-plus.json 1st pharyngeal groove|1st arch branchial groove|1st arch groove ectoderm|1st pharyngeal cleft|branchial groove of 1st arch|1st pharyngeal groove ectoderm|1st branchial cleft http://purl.obolibrary.org/obo/UBERON_0005872 GO:0043182 biolink:BiologicalProcess vacuolar sequestering of sodium ion The process of transporting sodium ions into, and confining within, a vacuole. go-plus.json vacuolar sequestration of sodium ion (Na+)|vacuolar sequestering of sodium ion (Na+)|sodium ion (Na+) storage in vacuole|sequestration of sodium ion (Na+) in vacuole|sodium ion (Na+) retention in vacuole|vacuolar sodium ion (Na+) retention|vacuolar sodium ion (Na+) storage|sequestering of sodium ion (Na+) in vacuole http://purl.obolibrary.org/obo/GO_0043182 GO:0043181 biolink:BiologicalProcess vacuolar sequestering The process of transporting a substance into, and confining within, a vacuole. go-plus.json vacuolar sequestration|sequestration in vacuole|storage in vacuole|retention in vacuole|sequestering in vacuole|vacuolar retention|vacuolar storage http://purl.obolibrary.org/obo/GO_0043181 GO:0043184 biolink:MolecularActivity vascular endothelial growth factor receptor 2 binding Binding to a vascular endothelial growth factor receptor 2. go-plus.json VEGF receptor 2 binding|VEGFR 2 binding|kinase domain region binding|KDR binding|Flk-1 binding http://purl.obolibrary.org/obo/GO_0043184 GO:0008859 biolink:MolecularActivity exoribonuclease II activity Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction. EC:3.1.13.1|MetaCyc:3.1.13.1-RXN go-plus.json ribonuclease Q|RNase II activity|ribonuclease II activity|5'-exoribonuclease activity|RNase II|BN ribonuclease activity|Escherichia coli exo-RNase II http://purl.obolibrary.org/obo/GO_0008859 GO:0043183 biolink:MolecularActivity vascular endothelial growth factor receptor 1 binding Binding to a vascular endothelial growth factor receptor 1. go-plus.json VEGF receptor 1 binding|VEGFR 1 binding|Flt-1 binding http://purl.obolibrary.org/obo/GO_0043183 GO:0008858 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008858 CHEBI:19281 biolink:ChemicalSubstance 2,2'-bithiophenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_19281 GO:0008857 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008857 GO:0008856 biolink:MolecularActivity exodeoxyribonuclease X activity Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes. EC:3.1.11.-|MetaCyc:3.1.22.5-RXN go-plus.json Escherichia coli endodeoxyribonuclease activity|deoxyribonuclease X activity|Escherichia coli endodeoxyribonuclease X activity http://purl.obolibrary.org/obo/GO_0008856 GO:0008855 biolink:MolecularActivity exodeoxyribonuclease VII activity Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides. EC:3.1.11.6|MetaCyc:3.1.11.6-RXN go-plus.json endodeoxyribonuclease VII|Escherichia coli exonuclease VII|E. coli exonuclease VII|E. coli exonuclease VII activity|exonuclease VII activity http://purl.obolibrary.org/obo/GO_0008855 GO:0043180 biolink:BiologicalProcess rhythmic inhibition Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit. go-plus.json http://purl.obolibrary.org/obo/GO_0043180 GO:0008854 biolink:MolecularActivity exodeoxyribonuclease V activity Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. EC:3.1.11.5|MetaCyc:3.1.11.5-RXN go-plus.json Escherichia coli exonuclease V|gene recBCD enzymes|E. coli exonuclease V|gene recBC endoenzyme|RecBC deoxyribonuclease activity|E. coli exonuclease V activity|gene recBC DNase activity|exonuclease V activity http://purl.obolibrary.org/obo/GO_0008854 GO:0008853 biolink:MolecularActivity exodeoxyribonuclease III activity Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides. EC:3.1.11.2|MetaCyc:3.1.11.2-RXN go-plus.json exonuclease III activity|Escherichia coli exonuclease III|E. coli exonuclease III|endoribonuclease III|E. coli exonuclease III activity http://purl.obolibrary.org/obo/GO_0008853 GO:0008852 biolink:MolecularActivity exodeoxyribonuclease I activity Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides. EC:3.1.11.1|MetaCyc:3.1.11.1-RXN go-plus.json exonuclease I activity|Escherichia coli exonuclease I|E. coli exonuclease I|E. coli exonuclease I activity http://purl.obolibrary.org/obo/GO_0008852 GO:0043189 biolink:CellularComponent H4/H2A histone acetyltransferase complex A multisubunit complex that catalyzes the acetylation of histones H4 and H2A. go-plus.json H4/H2A HAT complex http://purl.obolibrary.org/obo/GO_0043189 GO:0008851 biolink:MolecularActivity ethanolamine ammonia-lyase activity Catalysis of the reaction: ethanolamine = acetaldehyde + NH3. MetaCyc:ETHAMLY-RXN|RHEA:15313|EC:4.3.1.7 go-plus.json ethanolamine deaminase activity|ethanolamine ammonia-lyase (acetaldehyde-forming) activity http://purl.obolibrary.org/obo/GO_0008851 CHEBI:44247 biolink:ChemicalSubstance (15Z)-tetracosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44247 GO:0008850 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008850 CHEBI:44245 biolink:ChemicalSubstance menaquinone-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_44245 chebi_ph7_3 GO:0043186 biolink:CellularComponent P granule A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes. go-plus.json nuage|polar granule|germline granule http://purl.obolibrary.org/obo/GO_0043186 GO:0043185 biolink:MolecularActivity vascular endothelial growth factor receptor 3 binding Binding to a vascular endothelial growth factor receptor 3. go-plus.json VEGFR 3 binding|fms-like-tyrosine kinase (Flt)-4 binding|VEGF receptor 3 binding http://purl.obolibrary.org/obo/GO_0043185 GO:0043188 biolink:CellularComponent cell septum edging The cell wall material that surrounds the septum in fungal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0043188 CHEBI:915 biolink:ChemicalSubstance 2,4-dihydroxyhept-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_915 GO:0043187 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043187 CHEBI:138636 biolink:ChemicalSubstance 2-hydroxy-3-methyldodecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138636 chebi_ph7_3 CHEBI:58882 biolink:ChemicalSubstance phosphinothricin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58882 chebi_ph7_3 CHEBI:138635 biolink:ChemicalSubstance (R)-2-hydroxyhexadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_138635 chebi_ph7_3 CHEBI:58881 biolink:ChemicalSubstance N-acetyl-D-hexosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58881 chebi_ph7_3 CHEBI:138634 biolink:ChemicalSubstance 3-methylnonanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138634 chebi_ph7_3 CHEBI:138633 biolink:ChemicalSubstance 2-hydroxy-3-methylnonanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138633 chebi_ph7_3 CHEBI:2229 biolink:ChemicalSubstance 6-phospho-2-dehydro-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2229 CHEBI:138637 biolink:ChemicalSubstance 3-methyldodecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138637 chebi_ph7_3 UBERON:0005868 biolink:AnatomicalEntity maxillary prominence the paired dorsal prominences formed by bifurcation of the first pharyngeal arches in the embryo that unite with the ipsilateral medial nasal process to form the upper jaw go-plus.json maxillary process|embryonic maxillary process|maxillary process of embryo|prominentia maxilaris http://purl.obolibrary.org/obo/UBERON_0005868 UBERON:0005867 biolink:AnatomicalEntity mandibular prominence the paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip go-plus.json mandibular process|prominentia mandibularis|mandibular swelling http://purl.obolibrary.org/obo/UBERON_0005867 UBERON:0005866 biolink:AnatomicalEntity pre-cartilage condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. go-plus.json pre-chondrogenic condensation|precartilagenous condensation|precartilage condensation|prechondrogenic condensation http://purl.obolibrary.org/obo/UBERON_0005866 UBERON:0005865 biolink:AnatomicalEntity pre-muscle condensation go-plus.json pre muscle mass|premuscle mass http://purl.obolibrary.org/obo/UBERON_0005865 CHEBI:58887 biolink:ChemicalSubstance 1D-myo-inositol 2-(L-cysteiniumylamino)-2-deoxy-alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_58887 chebi_ph7_3 CHEBI:138632 biolink:ChemicalSubstance 2-hydroxy-3-methylundecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138632 chebi_ph7_3 CHEBI:58886 biolink:ChemicalSubstance 1D-myo-inositol 2-ammonio-2-deoxy-alpha-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_58886 chebi_ph7_3 CHEBI:138631 biolink:ChemicalSubstance heptadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_138631 chebi_ph7_3 UBERON:0005863 biolink:AnatomicalEntity cartilaginous condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. go-plus.json cartilagenous condensation|cartilage condensation|chondrogenic condensation http://purl.obolibrary.org/obo/UBERON_0005863 CHEBI:58885 biolink:ChemicalSubstance UDP-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58885 chebi_ph7_3 CHEBI:138630 biolink:ChemicalSubstance 2-hydroxyhexanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138630 chebi_ph7_3 CHEBI:58884 biolink:ChemicalSubstance (2R)-homocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58884 chebi_ph7_3 CHEBI:58883 biolink:ChemicalSubstance flavonolate 7-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_58883 CHEBI:2220 biolink:ChemicalSubstance 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_2220 chebi_ph7_3 GO:0008828 biolink:MolecularActivity dATP pyrophosphohydrolase activity Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate. MetaCyc:RXN0-384|Reactome:R-HSA-2395872|Reactome:R-HSA-2395818|EC:3.6.1.56 go-plus.json 2-hydroxy-ATP pyrophosphatase activity|2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity|2-hydroxy-adenosine triphosphate pyrophosphatase activity|2-hydroxy-(d)ATP pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0008828 GO:0043193 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043193 CHEBI:44230 biolink:ChemicalSubstance 6-(alpha-D-glucosaminyl)-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_44230 GO:0043192 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043192 GO:0008827 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008827 GO:0008826 biolink:MolecularActivity cysteine sulfinate desulfinase activity Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite. RHEA:28278|MetaCyc:RXN0-279 go-plus.json cysteine sulphinate desulphinase activity http://purl.obolibrary.org/obo/GO_0008826 GO:0043195 biolink:CellularComponent terminal bouton Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. NIF_Subcellular:sao187426937 go-plus.json presynaptic bouton|synaptic bouton|bouton|terminal button http://purl.obolibrary.org/obo/GO_0043195 CHEBI:20265 biolink:ChemicalSubstance lanostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20265 chebi_ph7_3 GO:0008825 biolink:MolecularActivity cyclopropane-fatty-acyl-phospholipid synthase activity Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid. EC:2.1.1.79|RHEA:11988|MetaCyc:2.1.1.79-RXN go-plus.json cyclopropane fatty acid synthetase activity|cyclopropane synthase activity|unsaturated-phospholipid methyltransferase activity|CFA synthase activity|cyclopropane fatty acid synthase activity|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)|cyclopropane synthetase activity http://purl.obolibrary.org/obo/GO_0008825 GO:0043194 biolink:CellularComponent axon initial segment Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment. NIF_Subcellular:sao256000789 go-plus.json initial segment http://purl.obolibrary.org/obo/GO_0043194 GO:0008824 biolink:MolecularActivity cyanate hydratase activity Catalysis of the reaction: cyanate + H2O = carbamate. UM-BBD_reactionID:r0608|MetaCyc:R524-RXN|RHEA:11120|EC:4.2.1.104 go-plus.json cyanate lyase activity|carbamate hydro-lyase activity|cyanate hydrolase activity|cyanate aminohydrolase activity|cyanate C-N-lyase activity|cyanase activity http://purl.obolibrary.org/obo/GO_0008824 GO:0008823 biolink:MolecularActivity cupric reductase activity Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH. MetaCyc:R170-RXN|EC:1.16.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0008823 GO:0008822 biolink:MolecularActivity obsolete crotonobetaine/carnitine-CoA ligase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json crotonobetaine/carnitine-CoA ligase activity http://purl.obolibrary.org/obo/GO_0008822 GO:0043191 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043191 GO:0008821 biolink:MolecularActivity crossover junction endodeoxyribonuclease activity Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction). EC:3.1.22.4|MetaCyc:3.1.22.4-RXN go-plus.json Holliday junction-cleaving endonuclease activity|endo X3|Hje endonuclease activity|SpCCe1 holliday junction resolvase|crossover junction endoribonuclease activity|SpCCe1 Holliday junction resolvase activity|endonuclease RuvC activity|Holliday junction-resolving endoribonuclease activity|RusA endonuclease activity|RuvC endonuclease activity|RusA Holliday junction resolvase activity|Endo X3 activity|endonuclease VII activity|endonuclease X3 activity|cruciform-cutting endonuclease activity|Holliday junction nuclease activity|endodeoxyribonuclease RUS activity|RusA holliday junction resolvase|Holliday junction endonuclease CCE1 activity|Holliday junction resolvase activity|resolving enzyme CCE1 activity http://purl.obolibrary.org/obo/GO_0008821 GO:0043190 biolink:CellularComponent ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. go-plus.json ABC-type efflux permease complex|mating pheromone exporter|ABC-type efflux porter complex|ABC-type uptake permease complex http://purl.obolibrary.org/obo/GO_0043190 goslim_pir|goslim_metagenomics GO:0008820 biolink:MolecularActivity cobinamide phosphate guanylyltransferase activity Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate. RHEA:22712|KEGG_REACTION:R05222|EC:2.7.7.62|MetaCyc:COBINPGUANYLYLTRANS-RXN go-plus.json CobU|GTP:adenosylcobinamide-phosphate guanylyltransferase activity|AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|adenosylcobinamide-phosphate guanylyltransferase activity|GTP:cobinamide phosphate guanylyltransferase activity|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase http://purl.obolibrary.org/obo/GO_0008820 CHEBI:138609 biolink:ChemicalSubstance short-chain (R)-3-hydroxy fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138609 chebi_ph7_3 CHEBI:44236 biolink:ChemicalSubstance (S)-NADHX go-plus.json http://purl.obolibrary.org/obo/CHEBI_44236 CHEBI:138608 biolink:ChemicalSubstance (S)-3-hydroxypentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138608 chebi_ph7_3 GO:0043197 biolink:CellularComponent dendritic spine A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. NIF_Subcellular:sao1799103720|Wikipedia:Dendritic_spine go-plus.json sessile dendritic spine|dendrite spine|branched dendritic spine|mushroom dendritic spine|stubby dendritic spine|thin dendritic spine http://purl.obolibrary.org/obo/GO_0043197 goslim_synapse GO:0043196 biolink:CellularComponent varicosity Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. go-plus.json http://purl.obolibrary.org/obo/GO_0043196 GO:0043199 biolink:MolecularActivity sulfate binding Binding to sulfate, SO4(2-), a negatively charged small molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043199 GO:0043198 biolink:CellularComponent dendritic shaft Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines. NIF_Subcellular:sao2034472720 go-plus.json trunk http://purl.obolibrary.org/obo/GO_0043198 CHEBI:58871 biolink:ChemicalSubstance 3,3'-biflaviolin 2,2'-diolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58871 CHEBI:138603 biolink:ChemicalSubstance (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138603 chebi_ph7_3 CHEBI:58870 biolink:ChemicalSubstance beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58870 chebi_ph7_3 CHEBI:138600 biolink:ChemicalSubstance 4,4'-diapolycopen-4-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138600 chebi_ph7_3 CHEBI:920 biolink:ChemicalSubstance 2,4-dinitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_920 chebi_ph7_3 CHEBI:138607 biolink:ChemicalSubstance (S)-3-hydroxypentanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138607 chebi_ph7_3 CHEBI:138605 biolink:ChemicalSubstance [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138605 chebi_ph7_3 CHEBI:138604 biolink:ChemicalSubstance [4-(6-methylheptanoyl)-5-oxo-2,5-dihydrofuran-3-yl]methyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138604 chebi_ph7_3 CHEBI:58879 biolink:ChemicalSubstance N-acetylphosphinothricin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58879 chebi_ph7_3 CHEBI:58878 biolink:ChemicalSubstance 2-oxo-1,2-dihydroquinoline-4-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58878 chebi_ph7_3 UBERON:0005856 biolink:AnatomicalEntity developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme. go-plus.json mesenchyme condensation http://purl.obolibrary.org/obo/UBERON_0005856 CHEBI:58877 biolink:ChemicalSubstance glycochenodeoxycholate 7-sulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58877 chebi_ph7_3 CHEBI:58876 biolink:ChemicalSubstance murideoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58876 chebi_ph7_3 CHEBI:58875 biolink:ChemicalSubstance hyodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58875 chebi_ph7_3 CHEBI:58874 biolink:ChemicalSubstance taurohyocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58874 chebi_ph7_3 GO:0008829 biolink:MolecularActivity dCTP deaminase activity Catalysis of the reaction: dCTP + H2O = dUTP + NH3. EC:3.5.4.13|MetaCyc:DCTP-DEAM-RXN|RHEA:22680|Reactome:R-HSA-180632 go-plus.json 5-methyl-dCTP deaminase activity|deoxycytidine triphosphate deaminase activity|dCTP aminohydrolase activity http://purl.obolibrary.org/obo/GO_0008829 CHEBI:58872 biolink:ChemicalSubstance 3,8'-biflaviolin 2,2'-diolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58872 GO:0008839 biolink:MolecularActivity 4-hydroxy-tetrahydrodipicolinate reductase Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+. MetaCyc:DIHYDROPICRED-RXN|EC:1.17.1.8 go-plus.json dihydrodipicolinic acid reductase activity|2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity|dihydrodipicolinate reductase activity http://purl.obolibrary.org/obo/GO_0008839 GO:0008838 biolink:MolecularActivity diaminopropionate ammonia-lyase activity Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3. RHEA:22084|MetaCyc:4.3.1.15-RXN|EC:4.3.1.15 go-plus.json 2,3-diaminopropionate ammonia-lyase activity|alpha,beta-diaminopropionate ammonia-lyase activity|diaminopropionatase activity|2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming) http://purl.obolibrary.org/obo/GO_0008838 GO:0008837 biolink:MolecularActivity diaminopimelate epimerase activity Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate. EC:5.1.1.7|RHEA:15393|MetaCyc:DIAMINOPIMEPIM-RXN|KEGG_REACTION:R02735 go-plus.json LL-2,6-diaminoheptanedioate 2-epimerase activity http://purl.obolibrary.org/obo/GO_0008837 GO:0008836 biolink:MolecularActivity diaminopimelate decarboxylase activity Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2). KEGG_REACTION:R00451|RHEA:15101|MetaCyc:DIAMINOPIMDECARB-RXN|EC:4.1.1.20 go-plus.json meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)|diaminopimelic acid decarboxylase activity|meso-2,6-diaminoheptanedioate carboxy-lyase activity|DAP-decarboxylase activity|DAP decarboxylase activity|meso-diaminopimelate decarboxylase activity http://purl.obolibrary.org/obo/GO_0008836 GO:0008835 biolink:MolecularActivity diaminohydroxyphosphoribosylaminopyrimidine deaminase activity Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+). MetaCyc:RIBOFLAVINSYNDEAM-RXN|RHEA:21868|KEGG_REACTION:R03459|EC:3.5.4.26 go-plus.json 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity|2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity|2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity http://purl.obolibrary.org/obo/GO_0008835 UBERON:0005838 biolink:AnatomicalEntity fasciculus of brain A fascicle that is part of a brain. go-plus.json brain fasciculus http://purl.obolibrary.org/obo/UBERON_0005838 GO:0008834 biolink:MolecularActivity di-trans,poly-cis-decaprenylcistransferase activity Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate. RHEA:27551|MetaCyc:RXN-8999|EC:2.5.1.31 go-plus.json undecaprenyl pyrophosphate synthase activity|undecaprenyl diphosphate synthase activity|bactoprenyl-diphosphate synthase activity|UPP synthetase activity|undecaprenyl-diphosphate synthase activity|undecaprenyl diphosphate synthetase activity|undecaprenyl pyrophosphate synthetase activity|di-trans,poly-cis-undecaprenyl-diphosphate synthase activity|di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity http://purl.obolibrary.org/obo/GO_0008834 GO:0008833 biolink:MolecularActivity deoxyribonuclease IV (phage-T4-induced) activity Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products. MetaCyc:3.1.21.2-RXN|EC:3.1.21.2 go-plus.json endonuclease IV activity|Escherichia coli endonuclease II|deoxriboendonuclease activity|endonuclease II|deoxyribonuclease IV (phage T4-induced) activity|endodeoxyribonuclease IV (phage T(4)-induced) activity|redoxyendonuclease activity|E. coli endonuclease IV|DNA-adenine-transferase activity|endodeoxyribonuclease IV (phage T4-induced) activity http://purl.obolibrary.org/obo/GO_0008833 UBERON:0005837 biolink:AnatomicalEntity fasciculus of spinal cord A fascicle that is part of a spinal cord. go-plus.json spinal cord fasciculus http://purl.obolibrary.org/obo/UBERON_0005837 GO:0008832 biolink:MolecularActivity dGTPase activity Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate. EC:3.1.5.1|RHEA:15193|MetaCyc:DGTPTRIPHYDRO-RXN|KEGG_REACTION:R01856 go-plus.json deoxy-GTPase activity|deoxyguanosine triphosphatase activity|deoxyguanosinetriphosphate triphosphohydrolase activity|deoxyguanosine 5-triphosphate triphosphohydrolase activity|dGTP triphosphohydrolase activity|deoxyguanosine triphosphate triphosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008832 CHEBI:58869 biolink:ChemicalSubstance N-(3-ammoniopropyl)-4-ammoniobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_58869 chebi_ph7_3 GO:0008831 biolink:MolecularActivity dTDP-4-dehydrorhamnose reductase activity Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH. EC:1.1.1.133|MetaCyc:DTDPDEHYRHAMREDUCT-RXN|KEGG_REACTION:R02777|RHEA:21796 go-plus.json dTDP-6-deoxy-L-mannose dehydrogenase activity|thymidine diphospho-4-ketorhamnose reductase activity|reductase, thymidine diphospho-4-ketorhamnose|dTDP-4-keto-L-rhamnose reductase activity|TDP-4-keto-rhamnose reductase activity|dTDP-4-ketorhamnose reductase activity|dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008831 GO:0008830 biolink:MolecularActivity dTDP-4-dehydrorhamnose 3,5-epimerase activity Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose. MetaCyc:DTDPDEHYDRHAMEPIM-RXN|RHEA:16969|EC:5.1.3.13|KEGG_REACTION:R06514 go-plus.json dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity|dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity|TDP-4-ketorhamnose 3,5-epimerase activity|TDP-4-keto-L-rhamnose-3,5-epimerase activity|thymidine diphospho-4-ketorhamnose 3,5-epimerase activity http://purl.obolibrary.org/obo/GO_0008830 CHEBI:2208 biolink:ChemicalSubstance purine-6-thiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_2208 chebi_ph7_3 CHEBI:138619 biolink:ChemicalSubstance D-alanyl-AMP zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138619 chebi_ph7_3 CHEBI:58860 biolink:ChemicalSubstance hydroxypyruvaldehyde phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58860 chebi_ph7_3 CHEBI:138611 biolink:ChemicalSubstance O-[S-(isoheptanoyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138611 chebi_ph7_3 CHEBI:58868 biolink:ChemicalSubstance 3,7-dideoxy-D-threo-hepto-2,6-diuolosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58868 chebi_ph7_3 UBERON:0005845 biolink:AnatomicalEntity caudal segment of spinal cord A spinal cord segment that adjacent_to a caudal region. go-plus.json segmenta coccygea medullae spinalis [1-3]|pars coccygea medullae spinalis|segmenta coccygea|coccygeal segment of spinal cord|coccygeal segments of spinal cord [1-3] http://purl.obolibrary.org/obo/UBERON_0005845 UBERON:0005844 biolink:AnatomicalEntity spinal cord segment go-plus.json spinal neuromeres|axial regional part of spinal cord|segment of spinal cord|axial part of spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 CHEBI:58866 biolink:ChemicalSubstance (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58866 chebi_ph7_3 CHEBI:58865 biolink:ChemicalSubstance N-carbamoyl-L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58865 chebi_ph7_3 CHEBI:138610 biolink:ChemicalSubstance O-[S-(2E)-isoheptenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138610 chebi_ph7_3 CHEBI:58864 biolink:ChemicalSubstance dehypoxanthine futalosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58864 chebi_ph7_3 CHEBI:58863 biolink:ChemicalSubstance futalosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58863 chebi_ph7_3 CHEBI:58862 biolink:ChemicalSubstance N(2)-(3-carboxylatopropionyl)-L-citrullinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58862 chebi_ph7_3 CHEBI:19298 biolink:ChemicalSubstance 2,3,5-trichloro-cis,cis-muconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_19298 chebi_ph7_3 CHEBI:58861 biolink:ChemicalSubstance 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58861 chebi_ph7_3 GO:0008806 biolink:MolecularActivity carboxymethylenebutenolidase activity Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate. MetaCyc:CARBOXYMETHYLENEBUTENOLIDASE-RXN|UM-BBD_enzymeID:e0066|EC:3.1.1.45|RHEA:12372 go-plus.json carboxymethylene butenolide hydrolase activity|dienelactone hydrolase activity|4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity|maleylacetate enol-lactonase activity http://purl.obolibrary.org/obo/GO_0008806 CHEBI:19252 biolink:ChemicalSubstance 2'-deoxyribonucleoside 3'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19252 GO:0008805 biolink:MolecularActivity carbon-monoxide oxygenase activity Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561. MetaCyc:RXN-21452|UM-BBD_reactionID:r0650|Wikipedia:Carbon-monoxide_dehydrogenase_(cytochrome_b-561)|EC:1.2.5.3|RHEA:48880 go-plus.json carbon monoxide oxygenase (cytochrome b-561) activity|carbon monoxide oxygenase activity|carbon monoxide oxidase activity|carbon monoxide:methylene blue oxidoreductase activity|carbon monoxide,water:cytochrome b-561 oxidoreductase activity|cytochrome b561|carbon-monoxide dehydrogenase (cytochrome b-561) http://purl.obolibrary.org/obo/GO_0008805 GO:0008804 biolink:MolecularActivity carbamate kinase activity Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate. EC:2.7.2.2|RHEA:10152|MetaCyc:CARBAMATE-KINASE-RXN go-plus.json carbamoyl phosphokinase activity|carbamyl phosphokinase activity|CKase activity|ATP:carbamate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008804 GO:0008803 biolink:MolecularActivity bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+). MetaCyc:3.6.1.41-RXN|KEGG_REACTION:R00125|EC:3.6.1.41|RHEA:24252 go-plus.json bis(5'-adenosyl) tetraphosphatase activity|diadenosine polyphosphate hydrolase activity|diadenosinetetraphosphatase (symmetrical) activity|symmetrical diadenosine tetraphosphate hydrolase activity|diadenosine tetraphosphate hydrolase activity|Ap4A hydrolase activity|adenosine tetraphosphate phosphodiesterase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity|dinucleosidetetraphosphate (symmetrical)|dinucleosidetetraphosphatase (symmetrical) activity|diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphatase activity|diadenosine tetraphosphatase (symmetrical)|Ap(4)A hydrolase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008803 GO:0008802 biolink:MolecularActivity betaine-aldehyde dehydrogenase activity Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+. Reactome:R-HSA-6797955|MetaCyc:BADH-RXN|RHEA:15305|EC:1.2.1.8 go-plus.json betaine-aldehyde:NAD+ oxidoreductase activity|betaine aldehyde oxidase activity|BetB|betaine aldehyde dehydrogenase activity|BADH activity http://purl.obolibrary.org/obo/GO_0008802 GO:0008801 biolink:MolecularActivity beta-phosphoglucomutase activity Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate. KEGG_REACTION:R02728|MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN|RHEA:20113|EC:5.4.2.6 go-plus.json beta-D-glucose 1,6-phosphomutase activity http://purl.obolibrary.org/obo/GO_0008801 CHEBI:58859 biolink:ChemicalSubstance 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58859 chebi_ph7_3 GO:0008800 biolink:MolecularActivity beta-lactamase activity Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. MetaCyc:BETA-LACTAMASE-RXN|RHEA:20401|EC:3.5.2.6 go-plus.json penicillinase I, II|neutrapen|exopenicillinase activity|cephalosporin-beta-lactamase activity|ampicillinase activity|beta-lactamase I-III|beta-lactam hydrolase activity|beta-lactamase A, B, C|beta-lactamase AME I|penicillin beta-lactamase activity|penicillin amido-beta-lactamhydrolase activity http://purl.obolibrary.org/obo/GO_0008800 CHEBI:58858 biolink:ChemicalSubstance N-(3-acetamidopropyl)-4-ammoniobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_58858 chebi_ph7_3 UBERON:0015238 biolink:AnatomicalEntity pineal complex A cluster in the epithalamus that consists of the pineal body and any associated structures, such as the parapineal gland or the parietal organ. The complex is poorly developed in mammals. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015238 CHEBI:44215 biolink:ChemicalSubstance NAD zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_44215 UBERON:0015234 biolink:AnatomicalEntity nucleus of ventral thalamus A nucleus of brain that is part of a ventral thalamus. go-plus.json ventral thalamic nucleus http://purl.obolibrary.org/obo/UBERON_0015234 UBERON:0015233 biolink:AnatomicalEntity nucleus of dorsal thalamus A nucleus of brain that is part of a dorsal thalamus. go-plus.json nucleus of thalamus proper|dorsal thalamic nucleus http://purl.obolibrary.org/obo/UBERON_0015233 CHEBI:2255 biolink:ChemicalSubstance 7beta-aminocephalosporanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2255 CHEBI:44219 biolink:ChemicalSubstance (4-amino-2-methylpyrimidin-5-yl)methyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44219 CHEBI:58856 biolink:ChemicalSubstance 2,3-trans-enoyl CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58856 chebi_ph7_3 CHEBI:58855 biolink:ChemicalSubstance secondary aliphatic ammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58855 chebi_ph7_3 CHEBI:58854 biolink:ChemicalSubstance 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58854 chebi_ph7_3 CHEBI:58853 biolink:ChemicalSubstance (2S,3S)-2-methylcitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58853 chebi_ph7_3 CHEBI:58852 biolink:ChemicalSubstance 5-deoxy-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58852 chebi_ph7_3 CHEBI:2251 biolink:ChemicalSubstance 7,8-dihydromethanopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_2251 GO:0008809 biolink:MolecularActivity carnitine racemase activity Catalysis of the reaction: D-carnitine = L-carnitine. MetaCyc:CARNRACE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008809 GO:0008808 biolink:MolecularActivity cardiolipin synthase activity Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol. MetaCyc:CARDIOLIPSYN-RXN|RHEA:31451 go-plus.json cardiolipin synthetase activity|cardiolipin synthetase 2 activity|diphosphatidylglycerol synthase activity|cardiolipin synthase 2 activity http://purl.obolibrary.org/obo/GO_0008808 CHEBI:58851 biolink:ChemicalSubstance 2-methyl-3-oxosuccinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58851 chebi_ph7_3 GO:0008807 biolink:MolecularActivity carboxyvinyl-carboxyphosphonate phosphorylmutase activity Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2. MetaCyc:2.7.8.23-RXN|EC:2.7.8.23|RHEA:14045 go-plus.json CPEP phosphonomutase activity|1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)|carboxyphosphonoenolpyruvate phosphonomutase activity http://purl.obolibrary.org/obo/GO_0008807 CHEBI:58850 biolink:ChemicalSubstance (3S)-3-hydroxy-L-asparagine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58850 chebi_ph7_3 GO:0008817 biolink:MolecularActivity cob(I)yrinic acid a,c-diamide adenosyltransferase activity Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin. Reactome:R-HSA-3322125|Reactome:R-HSA-3159253|EC:2.5.1.17|MetaCyc:COBALADENOSYLTRANS-RXN|RHEA:14725 go-plus.json ATP:corrinoid adenosyltransferase activity|vitamin B12s adenosyltransferase activity|CobA|ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity|ATP:cob(I)alamin cobeta-adenosyltransferase activity|aquocob(I)alamin vitamin B12s adenosyltransferase activity|cob(I)alamin adenosyltransferase activity|aquacob(I)alamin adenosyltransferase activity|ATP:cob(I)alamin Co-beta-adenosyltransferase activity http://purl.obolibrary.org/obo/GO_0008817 GO:0008816 biolink:MolecularActivity citryl-CoA lyase activity Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate. MetaCyc:CITRYLY-RXN|RHEA:20812|EC:4.1.3.34 go-plus.json (3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)|(3S)-citryl-CoA oxaloacetate-lyase activity http://purl.obolibrary.org/obo/GO_0008816 GO:0008815 biolink:MolecularActivity citrate (pro-3S)-lyase activity Catalysis of the reaction: citrate = acetate + oxaloacetate. RHEA:10760|KEGG_REACTION:R00362|EC:4.1.3.6|MetaCyc:CITLY-RXN go-plus.json citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]|citrase activity|citrate aldolase activity|citrate oxaloacetate-lyase activity|citridesmolase activity|citrate lyase activity|citrate lyase|citratase activity|citric aldolase activity|citritase activity http://purl.obolibrary.org/obo/GO_0008815 GO:0008814 biolink:MolecularActivity citrate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA. RHEA:19405|EC:2.8.3.10|MetaCyc:CITTRANS-RXN go-plus.json acetyl-CoA:citrate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0008814 GO:0008813 biolink:MolecularActivity chorismate lyase activity Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate. EC:4.1.3.40|MetaCyc:CHORPYRLY-RXN|KEGG_REACTION:R01302|RHEA:16505 go-plus.json CL|UbiC|CPL|chorismate pyruvate lyase activity|chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity|4-hydroxybenzoate synthetase activity http://purl.obolibrary.org/obo/GO_0008813 GO:0008812 biolink:MolecularActivity choline dehydrogenase activity Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde. KEGG_REACTION:R01025|MetaCyc:CHD-RXN|RHEA:17433|EC:1.1.99.1|Reactome:R-HSA-6797961 go-plus.json choline-cytochrome c reductase activity|choline:(acceptor) 1-oxidoreductase activity|choline:(acceptor) oxidoreductase activity|choline:acceptor 1-oxidoreductase activity|choline oxidase activity http://purl.obolibrary.org/obo/GO_0008812 CHEBI:58849 biolink:ChemicalSubstance N,N-dihydroxypentahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58849 chebi_ph7_3 GO:0008811 biolink:MolecularActivity chloramphenicol O-acetyltransferase activity Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA. KEGG_REACTION:R03065|RHEA:18421|EC:2.3.1.28|MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN go-plus.json chloramphenicol transacetylase activity|chloramphenicol acetylase activity|CAT II|acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity|CAT III|CAT I|chloramphenicol acetyltransferase activity http://purl.obolibrary.org/obo/GO_0008811 CHEBI:58848 biolink:ChemicalSubstance N,N-dihydroxytetrahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58848 chebi_ph7_3 GO:0008810 biolink:MolecularActivity cellulase activity Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. EC:3.2.1.4|MetaCyc:RXN-2043 go-plus.json celludextrinase activity|endoglucanase D|celluase A|alkali cellulase activity|carboxymethyl cellulase activity|9.5 cellulase activity|avicelase activity|cellulase A 3|endo-1,4-beta-D-glucanase activity|1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity|cellulosin AP|beta-1,4-endoglucan hydrolase activity|pancellase SS|endoglucanase activity|endo-1,4-beta-D-glucanohydrolase activity|beta-1,4-glucanase activity|endo-1,4-beta-glucanase activity http://purl.obolibrary.org/obo/GO_0008810 CHEBI:58847 biolink:ChemicalSubstance N,N-dihydroxytrihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58847 chebi_ph7_3 UBERON:0015228 biolink:AnatomicalEntity circulatory organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. go-plus.json circulatory vessel|heart or heart like organ|heart|cardiac pump|cardiac structure http://purl.obolibrary.org/obo/UBERON_0015228 UBERON:0015225 biolink:AnatomicalEntity atrial foramen intermedium A anatomical conduit that is part of a atrial septum intermedium. go-plus.json ostium intermedium|interatrial ostium intermedium http://purl.obolibrary.org/obo/UBERON_0015225 UBERON:0015224 biolink:AnatomicalEntity interventricular foramen intermedium A anatomical conduit that is part of a ventricular septum intermedium. go-plus.json interventricular ostium intermedium http://purl.obolibrary.org/obo/UBERON_0015224 CHEBI:34892 biolink:ChemicalSubstance nocodazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_34892 chebi_ph7_3 CHEBI:44209 biolink:ChemicalSubstance methylamino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_44209 CHEBI:19239 biolink:ChemicalSubstance 2'-deoxyadenosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19239 CHEBI:58846 biolink:ChemicalSubstance N,N-dihydroxydihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58846 chebi_ph7_3 CHEBI:19237 biolink:ChemicalSubstance 2'-deoxyadenosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19237 CHEBI:58845 biolink:ChemicalSubstance N,N-dihydroxyhexahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58845 chebi_ph7_3 CHEBI:58844 biolink:ChemicalSubstance N-hydroxyhexahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58844 chebi_ph7_3 NCBITaxon:7069 biolink:OrganismalEntity Tribolium go-plus.json Tribolium http://purl.obolibrary.org/obo/NCBITaxon_7069 CHEBI:58843 biolink:ChemicalSubstance N-hydroxypentahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58843 chebi_ph7_3 CHEBI:2260 biolink:ChemicalSubstance 7-deoxyloganic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2260 CHEBI:58842 biolink:ChemicalSubstance N-hydroxytetrahomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58842 chebi_ph7_3 CHEBI:58841 biolink:ChemicalSubstance N-hydroxytrihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58841 chebi_ph7_3 CHEBI:58840 biolink:ChemicalSubstance N-hydroxydihomomethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58840 chebi_ph7_3 GO:0008819 biolink:MolecularActivity cobinamide kinase activity Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0008819 NCBITaxon:7065 biolink:OrganismalEntity Tenebrionidae go-plus.json darkling beetles|Lagriidae|darkling ground beetles|long-jointed beetles http://purl.obolibrary.org/obo/NCBITaxon_7065 OBA:0003797 biolink:OntologyClass axon size The size of a axon. go-plus.json size of axon http://purl.obolibrary.org/obo/OBA_0003797 GO:0008818 biolink:MolecularActivity cobalamin 5'-phosphate synthase activity Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP. MetaCyc:COBALAMIN5PSYN-RXN|RHEA:23560 go-plus.json http://purl.obolibrary.org/obo/GO_0008818 CHEBI:19274 biolink:ChemicalSubstance 2'-deoxymugineic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19274 CHEBI:58839 biolink:ChemicalSubstance N(6)-dihydrolipoyl-L-lysinium(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_58839 chebi_ph7_3 CHEBI:58838 biolink:ChemicalSubstance CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58838 chebi_ph7_3 CHEBI:58837 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58837 chebi_ph7_3 CHEBI:58836 biolink:ChemicalSubstance hexahomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58836 chebi_ph7_3 UBERON:0015212 biolink:AnatomicalEntity lateral structure Any structure that is placed on one side of the left-right axis of a bilaterian. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015212 UBERON:0015214 biolink:AnatomicalEntity arcuate ligament A ligament that is part of a diaphragm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015214 UBERON:0005893 biolink:AnatomicalEntity leg bone A bone that is part of the region of the hindlimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. Counter-examples: any pes phalanx go-plus.json http://purl.obolibrary.org/obo/UBERON_0005893 UBERON:0005891 biolink:AnatomicalEntity coelomic epithelium The epithelial lining of the surface of the coelom. go-plus.json germinal epithelium of Waldeyer|celomic epithelium http://purl.obolibrary.org/obo/UBERON_0005891 CHEBI:34862 biolink:ChemicalSubstance N-(30-(9Z,12Z-octadecadienoyloxy)-tricontanoyl)-sphing-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_34862 chebi_ph7_3 CHEBI:58835 biolink:ChemicalSubstance pentahomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58835 chebi_ph7_3 CHEBI:58834 biolink:ChemicalSubstance tetrahomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58834 chebi_ph7_3 UBERON:0005899 biolink:AnatomicalEntity pes bone A bone that is part of the pes skeleton go-plus.json bone of pedal skeleton|bone of foor proper or tarsal skeleton|bone of foot|foot bone|bone of pes http://purl.obolibrary.org/obo/UBERON_0005899 CHEBI:58833 biolink:ChemicalSubstance trihomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58833 chebi_ph7_3 CHEBI:58832 biolink:ChemicalSubstance dihomomethionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58832 chebi_ph7_3 UBERON:0005897 biolink:AnatomicalEntity manus bone A bone that is part of the manus skeleton. Note that this includes the carpal bones. go-plus.json forelimb autopod bone|bone of hand|bone of pectoral limb autopodium|hand bone|bone of hand skeleton|bone of manus|forelimb autopodium bone|bone of pectoral limb autopod http://purl.obolibrary.org/obo/UBERON_0005897 CHEBI:58831 biolink:ChemicalSubstance iminoaspartate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58831 CHEBI:58830 biolink:ChemicalSubstance (2S)-2-hydroxy-3-oxobutyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58830 chebi_ph7_3 UBERON:0005895 biolink:AnatomicalEntity insect leg The walking appendages of each segment of the ventral adult external thorax[FBbt]. A leg derived from an imaginal disc[GO]. go-plus.json imaginal disc-derived leg http://purl.obolibrary.org/obo/UBERON_0005895 CHEBI:19260 biolink:ChemicalSubstance 2'-deoxyribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_19260 CHEBI:58828 biolink:ChemicalSubstance 5-(methylsulfanyl)-2,3-dioxopentyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58828 chebi_ph7_3 CHEBI:58827 biolink:ChemicalSubstance precorrin-2(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58827 chebi_ph7_3 CHEBI:58826 biolink:ChemicalSubstance N-acetyl-beta-D-glucosamine 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58826 chebi_ph7_3 PO:0005702 biolink:OntologyClass aerenchyma A portion of parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. go-plus.json portion of aerenchyma tissue (related)|通気組織 (Japanese, exact)|aerénquima (Spanish, exact) http://purl.obolibrary.org/obo/PO_0005702 CHEBI:58825 biolink:ChemicalSubstance (R)-beta-alanopine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58825 chebi_ph7_3 CHEBI:978 biolink:ChemicalSubstance 2-(1-hydroxyethyl)thiamine diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_978 UBERON:0005882 biolink:AnatomicalEntity neural tube alar plate The mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses. go-plus.json alar plate|alar plate of neural tube|sensory part of neural tube|alar lamina|lamina alaris|dorsal part of neural tube|lamina dorsolateralis http://purl.obolibrary.org/obo/UBERON_0005882 NCBITaxon:7041 biolink:OrganismalEntity Coleoptera go-plus.json beetles|beetles http://purl.obolibrary.org/obo/NCBITaxon_7041 UBERON:0005881 biolink:AnatomicalEntity autopodial extension A subdivision of the autopod that corresponds to one or more bones arranged in series branching from the main limb axis. go-plus.json digit or predigit|limb outgrowth http://purl.obolibrary.org/obo/UBERON_0005881 CHEBI:2247 biolink:ChemicalSubstance 7,8-diaminononanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2247 CHEBI:58824 biolink:ChemicalSubstance sulfonatoacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58824 chebi_ph7_3 CHEBI:58822 biolink:ChemicalSubstance tuberculosinyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58822 chebi_ph7_3 CHEBI:19257 biolink:ChemicalSubstance 2'-deoxyribonucleoside monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19257 CHEBI:58821 biolink:ChemicalSubstance terpentedienyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58821 chebi_ph7_3 CHEBI:58820 biolink:ChemicalSubstance lavandulyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58820 chebi_ph7_3 CHEBI:19255 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_19255 UBERON:0005884 biolink:AnatomicalEntity hyoid arch skeleton A subdivision of skeleton that supports pharyngeal arch 2. go-plus.json hyoid arch skeleton|pharyngeal arch 2 skeleton|hyoid bars|visceral arch 2|hyoid arch http://purl.obolibrary.org/obo/UBERON_0005884 CHEBI:19254 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_19254 chebi_ph7_3 GO:0018371 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018371 GO:0018370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018370 GO:0043333 biolink:MolecularActivity 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. EC:2.1.1.201|MetaCyc:2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN go-plus.json 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity http://purl.obolibrary.org/obo/GO_0043333 GO:0043332 biolink:CellularComponent mating projection tip The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth. go-plus.json shmoo tip|conjugation tube tip http://purl.obolibrary.org/obo/GO_0043332 GO:0043335 biolink:BiologicalProcess protein unfolding The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state. go-plus.json http://purl.obolibrary.org/obo/GO_0043335 GO:0043334 biolink:MolecularActivity 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. go-plus.json 2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity http://purl.obolibrary.org/obo/GO_0043334 GO:0043331 biolink:BiologicalProcess response to dsRNA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. go-plus.json response to double-stranded RNA http://purl.obolibrary.org/obo/GO_0043331 GO:0043330 biolink:BiologicalProcess response to exogenous dsRNA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus. go-plus.json response to viral dsRNA|response to exogenous double-stranded RNA http://purl.obolibrary.org/obo/GO_0043330 CHEBI:138229 biolink:ChemicalSubstance N-acetyl-alpha-D-muramic acid 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138229 CHEBI:138228 biolink:ChemicalSubstance beta-heptaprene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138228 chebi_ph7_3 CHEBI:138227 biolink:ChemicalSubstance beta-hexaprene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138227 chebi_ph7_3 CHEBI:138226 biolink:ChemicalSubstance beta-geranylfarnesene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138226 chebi_ph7_3 GO:0043337 biolink:MolecularActivity CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol. Reactome:R-HSA-1483063|RHEA:32931|MetaCyc:RXN-8141 go-plus.json cardiolipin synthetase|cardiolipin synthase http://purl.obolibrary.org/obo/GO_0043337 GO:0043336 biolink:MolecularActivity site-specific telomere resolvase activity Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases. go-plus.json ResT|TelN http://purl.obolibrary.org/obo/GO_0043336 GO:0018369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018369 GO:0043339 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043339 GO:0043338 biolink:MolecularActivity CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol. EC:2.7.7.67|RHEA:25690 go-plus.json CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase http://purl.obolibrary.org/obo/GO_0043338 GO:0018366 biolink:BiologicalProcess chiral amino acid racemization The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0018366 CHEBI:138221 biolink:ChemicalSubstance CDP-D-ribulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_138221 GO:0018365 biolink:MolecularActivity protein-serine epimerase activity Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine. RHEA:10660|MetaCyc:5.1.1.16-RXN|EC:5.1.1.16 go-plus.json protein-serine racemase activity http://purl.obolibrary.org/obo/GO_0018365 CHEBI:138220 biolink:ChemicalSubstance N-hexadecanoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138220 chebi_ph7_3 GO:0018368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018368 GO:0018367 biolink:BiologicalProcess obsolete free L-amino acid racemization OBSOLETE. (Was not defined before being made obsolete). go-plus.json free L-amino acid racemization http://purl.obolibrary.org/obo/GO_0018367 GO:0018362 biolink:BiologicalProcess peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester. RESID:AA0279 go-plus.json peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester http://purl.obolibrary.org/obo/GO_0018362 CHEBI:138225 biolink:ChemicalSubstance CDP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_138225 CHEBI:138224 biolink:ChemicalSubstance (13R)-epi-8,13-epoxylabd-14-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138224 chebi_ph7_3 GO:0018361 biolink:BiologicalProcess peptidyl-glutamine 2-methylation The methylation of glutamine to form 2-methyl-L-glutamine. RESID:AA0273 go-plus.json http://purl.obolibrary.org/obo/GO_0018361 CHEBI:138223 biolink:ChemicalSubstance ent-copal-8-ol diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138223 chebi_ph7_3 GO:0018364 biolink:BiologicalProcess peptidyl-glutamine methylation The addition of a methyl group to a glutamine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018364 CHEBI:138222 biolink:ChemicalSubstance N-oleoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138222 chebi_ph7_3 GO:0018363 biolink:BiologicalProcess peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium. RESID:AA0280 go-plus.json peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulphonium|peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium http://purl.obolibrary.org/obo/GO_0018363 GO:0018380 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018380 GO:0018382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018382 GO:0018381 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018381 GO:0033999 biolink:MolecularActivity chondroitin B lyase activity Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate. EC:4.2.2.19|MetaCyc:4.2.2.19-RXN go-plus.json dermatan sulfate lyase activity|chonB|ChnB|chondroitinase B activity http://purl.obolibrary.org/obo/GO_0033999 GO:0033998 biolink:MolecularActivity inulin fructotransferase (DFA-III-forming) activity Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. EC:4.2.2.18|MetaCyc:4.2.2.18-RXN go-plus.json inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity|inulinase II activity|inulin fructotransferase (DFA-III-producing) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity|inulin fructotransferase (depolymerizing) activity|inulase II activity http://purl.obolibrary.org/obo/GO_0033998 GO:0033997 biolink:MolecularActivity inulin fructotransferase (DFA-I-forming) activity Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. EC:4.2.2.17|MetaCyc:4.2.2.17-RXN go-plus.json inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity|inulin fructotransferase (DFA-I-producing) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity http://purl.obolibrary.org/obo/GO_0033997 GO:0043344 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043344 GO:0043343 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043343 GO:0043346 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043346 GO:0043345 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043345 GO:0043340 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043340 GO:0043342 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043342 GO:0043341 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043341 CHEBI:138239 biolink:ChemicalSubstance N-oleoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138239 CHEBI:138238 biolink:ChemicalSubstance pyrimidine ribonucleoside 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138238 chebi_ph7_3 CHEBI:138237 biolink:ChemicalSubstance 2-hydroxy-7,8-dihydropteroic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138237 GO:0043348 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043348 GO:0043347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043347 GO:0043349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043349 GO:0018377 biolink:BiologicalProcess protein myristoylation The covalent attachment of a myristoyl group to a protein. go-plus.json protein amino acid myristoylation http://purl.obolibrary.org/obo/GO_0018377 GO:0033996 biolink:MolecularActivity levan fructotransferase (DFA-IV-forming) activity Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide. EC:4.2.2.16|MetaCyc:4.2.2.16-RXN go-plus.json levan fructotransferase activity|2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity|2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity http://purl.obolibrary.org/obo/GO_0033996 CHEBI:138232 biolink:ChemicalSubstance peregrinol diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138232 chebi_ph7_3 GO:0033995 biolink:MolecularActivity anhydrosialidase activity Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate. EC:4.2.2.15|MetaCyc:4.2.2.15-RXN go-plus.json sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity|sialidase L activity|glycoconjugate sialyl-lyase (2,7-cyclizing) activity|anhydroneuraminidase activity http://purl.obolibrary.org/obo/GO_0033995 GO:0018376 biolink:BiologicalProcess peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16). RESID:AA0026 go-plus.json http://purl.obolibrary.org/obo/GO_0018376 GO:0033994 biolink:MolecularActivity glucuronan lyase activity Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides. EC:4.2.2.14|MetaCyc:4.2.2.14-RXN go-plus.json (1,4)-beta-D-glucuronan lyase activity http://purl.obolibrary.org/obo/GO_0033994 GO:0018379 biolink:BiologicalProcess cytochrome c-heme linkage via heme-bis-L-cysteine The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine. RESID:AA0134 go-plus.json cytochrome c-haem linkage via haem-bis-L-cysteine http://purl.obolibrary.org/obo/GO_0018379 GO:0033993 biolink:BiologicalProcess response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0033993 GO:0018378 biolink:BiologicalProcess cytochrome c-heme linkage via heme-L-cysteine The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine. RESID:AA0135 go-plus.json cytochrome c-haem linkage via haem-L-cysteine http://purl.obolibrary.org/obo/GO_0018378 GO:0033992 biolink:MolecularActivity 1,5-anhydro-D-fructose dehydratase activity Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O. RHEA:15725|MetaCyc:4.2.1.111-RXN|EC:4.2.1.111 go-plus.json AF dehydratase activity|AFDH|1,5-anhydro-D-fructose hydrolyase activity|1,5-anhydro-D-fructose 4-dehydratase activity|1,5-anhydro-D-fructose hydro-lyase activity|1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity|1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity http://purl.obolibrary.org/obo/GO_0033992 GO:0018373 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018373 GO:0033991 biolink:MolecularActivity aldos-2-ulose dehydratase activity Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one. RHEA:12100|MetaCyc:4.2.1.110-RXN|EC:4.2.1.110 go-plus.json pyranosone dehydratase activity|1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity|AUDH|1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity http://purl.obolibrary.org/obo/GO_0033991 GO:0018372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018372 GO:0018375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018375 GO:0033990 biolink:MolecularActivity ectoine synthase activity Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O. KEGG_REACTION:R06979|MetaCyc:R103-RXN|EC:4.2.1.108|RHEA:17281 go-plus.json 4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|EctC|N-acetyldiaminobutyrate dehydratase activity|N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|L-ectoine synthase activity|N-acetyldiaminobutanoate dehydratase activity http://purl.obolibrary.org/obo/GO_0033990 CHEBI:138234 biolink:ChemicalSubstance (13R)-manoyl oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_138234 chebi_ph7_3 GO:0018374 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018374 CHEBI:138233 biolink:ChemicalSubstance 9,13(R)-epoxylabd-14-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138233 chebi_ph7_3 GO:0033989 biolink:MolecularActivity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O. RHEA:18933|EC:4.2.1.107|Reactome:R-HSA-192331|Reactome:R-HSA-193535|MetaCyc:4.2.1.107-RXN go-plus.json (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity|D-3-hydroxyacyl-CoA dehydratase activity|(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity|46 kDa hydratase 2 activity http://purl.obolibrary.org/obo/GO_0033989 GO:0033988 biolink:MolecularActivity bile-acid 7alpha-dehydratase activity Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O. EC:4.2.1.106|RHEA:10436|KEGG_REACTION:R07318|MetaCyc:4.2.1.106-RXN go-plus.json 7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity|BA7 alpha dehydratase activity|7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0033988 GO:0033987 biolink:MolecularActivity 2-hydroxyisoflavanone dehydratase activity Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O. RHEA:16445|EC:4.2.1.105|MetaCyc:RXN-3284 go-plus.json 2,7,4'-trihydroxyisoflavanone hydro-lyase activity|2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity http://purl.obolibrary.org/obo/GO_0033987 GO:0033986 biolink:BiologicalProcess response to methanol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0033986 GO:0043355 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043355 GO:0043354 biolink:BiologicalProcess enucleate erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus. go-plus.json enucleate red blood cell maturation|enucleate RBC maturation http://purl.obolibrary.org/obo/GO_0043354 GO:0043357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043357 GO:0043356 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043356 GO:0043351 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043351 GO:0043350 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043350 GO:0043353 biolink:BiologicalProcess enucleate erythrocyte differentiation The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus. go-plus.json enucleate red blood cell differentiation|enucleate RBC differentiation http://purl.obolibrary.org/obo/GO_0043353 GO:0043352 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043352 CHEBI:138206 biolink:ChemicalSubstance (13R)-S-cysteinylglycinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138206 GO:0043359 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043359 GO:0018348 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018348 GO:0043358 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043358 GO:0018347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018347 CHEBI:138209 biolink:ChemicalSubstance (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138209 GO:0018349 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018349 CHEBI:138208 biolink:ChemicalSubstance carotenoid biosynthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_138208 GO:0018344 biolink:BiologicalProcess protein geranylgeranylation The covalent attachment of a geranylgeranyl group to a protein. go-plus.json C-terminal protein geranylgeranylation|protein amino acid geranylgeranylation http://purl.obolibrary.org/obo/GO_0018344 GO:0033985 biolink:CellularComponent acidocalcisome lumen The volume enclosed by the membranes of an acidocalcisome. go-plus.json http://purl.obolibrary.org/obo/GO_0033985 GO:0033984 biolink:MolecularActivity indole-3-glycerol-phosphate lyase activity Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate. EC:4.1.2.8|KEGG_REACTION:R02340|RHEA:14081|MetaCyc:4.1.2.8-RXN|MetaCyc:RXN0-2381 go-plus.json indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity|TSA|indole synthase activity|BX1|tryptophan synthase alpha activity|tryptophan synthase alpha subunit activity|indole-3-glycerol phosphate lyase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity|IGL|indoleglycerolphosphate aldolase activity|indole glycerol phosphate hydrolase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity http://purl.obolibrary.org/obo/GO_0033984 GO:0018343 biolink:BiologicalProcess protein farnesylation The covalent attachment of a farnesyl group to a protein. go-plus.json C-terminal protein farnesylation|protein amino acid farnesylation http://purl.obolibrary.org/obo/GO_0018343 GO:0033983 biolink:MolecularActivity diaminobutyrate decarboxylase activity Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2). KEGG_REACTION:R07650|MetaCyc:4.1.1.86-RXN|EC:4.1.1.86|RHEA:15689 go-plus.json L-2,4-diaminobutyrate decarboxylase activity|L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity|L-2,4-diaminobutanoate carboxy-lyase activity|DABA DC http://purl.obolibrary.org/obo/GO_0033983 CHEBI:2030 biolink:ChemicalSubstance 5-aminoimidazole-4-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_2030 chebi_ph7_3 GO:0018346 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018346 GO:0033982 biolink:MolecularActivity 3-dehydro-L-gulonate-6-phosphate decarboxylase activity Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2). KEGG_REACTION:R07125|RHEA:14353|EC:4.1.1.85|MetaCyc:RXN0-705 go-plus.json 3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity|SgaH|UlaD|SgbH|KGPDC|3-keto-L-gulonate 6-phosphate decarboxylase activity|3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0033982 GO:0018345 biolink:BiologicalProcess protein palmitoylation The covalent attachment of a palmitoyl group to a protein. go-plus.json protein amino acid palmitoylation http://purl.obolibrary.org/obo/GO_0018345 GO:0018340 biolink:BiologicalProcess peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine. RESID:AA0264 go-plus.json peptidyl-O-(sn-1-glycerophosphoryl)-L-serine formation from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine synthesis from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine anabolism from peptidyl-serine http://purl.obolibrary.org/obo/GO_0018340 GO:0033981 biolink:MolecularActivity D-dopachrome decarboxylase activity Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2). RHEA:18441|MetaCyc:4.1.1.84-RXN|EC:4.1.1.84|KEGG_REACTION:R07313 go-plus.json phenylpyruvate tautomerase II activity|dopachrome conversion activity|D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity|D-tautomerase activity|D-dopachrome carboxy-lyase activity|D-dopachrome tautomerase activity|dopachrome decarboxylase activity http://purl.obolibrary.org/obo/GO_0033981 GO:0033980 biolink:MolecularActivity phosphonopyruvate decarboxylase activity Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde. KEGG_REACTION:R04053|MetaCyc:4.1.1.82-RXN|RHEA:20768|EC:4.1.1.82 go-plus.json 3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity|3-phosphonopyruvate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0033980 CHEBI:138202 biolink:ChemicalSubstance (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138202 GO:0018342 biolink:BiologicalProcess protein prenylation The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added. go-plus.json C-terminal protein prenylation|protein amino acid prenylation http://purl.obolibrary.org/obo/GO_0018342 CHEBI:138201 biolink:ChemicalSubstance 18-hydroxyleukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138201 GO:0018341 biolink:BiologicalProcess peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine. go-plus.json peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthetic process|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine anabolism|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine synthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine formation http://purl.obolibrary.org/obo/GO_0018341 CHEBI:138200 biolink:ChemicalSubstance 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138200 chebi_ph7_3 CHEBI:44185 biolink:ChemicalSubstance methotrexate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44185 GO:0018360 biolink:BiologicalProcess protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine. RESID:AA0271 go-plus.json protein-haem P460 linkage via haem P460-bis-L-cysteine-L-lysine http://purl.obolibrary.org/obo/GO_0018360 GO:0043360 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043360 GO:0033979 biolink:BiologicalProcess box H/ACA RNA metabolic process The chemical reactions and pathways involving box H/ACA type small nucleolar RNA. go-plus.json box H/ACA sRNA metabolic process|box H/ACA snoRNA metabolic process http://purl.obolibrary.org/obo/GO_0033979 GO:0033978 biolink:MolecularActivity phosphonopyruvate hydrolase activity Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate. MetaCyc:3.11.1.3-RXN|RHEA:16673|KEGG_REACTION:R08200|EC:3.11.1.3 go-plus.json PPH http://purl.obolibrary.org/obo/GO_0033978 GO:0033977 biolink:MolecularActivity 2-haloacid dehalogenase (configuration-retaining) activity Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide. MetaCyc:3.8.1.11-RXN|EC:3.8.1.11|RHEA:12072 go-plus.json DL-2-haloacid dehalogenase activity|DL-DEXr|2-haloalkanoic acid dehalogenase activity|2-haloalkanoid acid halidohydrolase activity http://purl.obolibrary.org/obo/GO_0033977 GO:0033976 biolink:MolecularActivity 2-haloacid dehalogenase (configuration-inverting) activity Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide. MetaCyc:3.8.1.10-RXN go-plus.json DL-2-haloacid dehalogenase activity|2-haloalkanoic acid dehalogenase activity|DL-DEXi|DL-2-haloacid halidohydrolase (inversion of configuration) activity|DL-2-haloacid dehalogenase (inversion of configuration) activity|2-haloalkanoid acid halidohydrolase activity http://purl.obolibrary.org/obo/GO_0033976 GO:0033975 biolink:MolecularActivity (R)-2-haloacid dehalogenase activity Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide. MetaCyc:3.8.1.9-RXN|EC:3.8.1.9 go-plus.json (R)-2-haloacid halidohydrolase activity|2-haloalkanoic acid dehalogenase activity|D-DEX|D-2-haloacid dehalogenase activity|2-haloalkanoid acid halidohydrolase activity http://purl.obolibrary.org/obo/GO_0033975 GO:0043366 biolink:BiologicalProcess beta selection The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043366 GO:0043365 biolink:MolecularActivity [formate-C-acetyltransferase]-activating enzyme activity Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical. MetaCyc:TDCEACT-RXN|RHEA:19225|EC:1.97.1.4 go-plus.json formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity|formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)|formate-C-acetyltransferase-activating enzyme|[pyruvate formate-lyase]-activating enzyme activity|pyruvate formate-lyase-activating enzyme|PFL activase activity|PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity|formate acetyltransferase activating enzyme activity http://purl.obolibrary.org/obo/GO_0043365 GO:0043368 biolink:BiologicalProcess positive T cell selection The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. go-plus.json positive T-cell selection|positive T-lymphocyte selection|positive T lymphocyte selection http://purl.obolibrary.org/obo/GO_0043368 GO:0043367 biolink:BiologicalProcess CD4-positive, alpha-beta T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. go-plus.json CD4-positive, alpha-beta T lymphocyte differentiation|CD4-positive, alpha beta T cell differentiation|CD4-positive, alpha beta T cell development|CD4-positive, alpha-beta T-cell differentiation|CD4-positive, alpha-beta T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043367 GO:0043362 biolink:BiologicalProcess nucleate erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus. go-plus.json nucleate red blood cell maturation|nucleate RBC maturation http://purl.obolibrary.org/obo/GO_0043362 GO:0043361 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043361 GO:0043364 biolink:MolecularActivity glycyl-radical enzyme activating activity Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM). EC:1.97.1.- go-plus.json catalysis of free radical formation http://purl.obolibrary.org/obo/GO_0043364 goslim_pir GO:0043363 biolink:BiologicalProcess nucleate erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds. go-plus.json nucleate red blood cell differentiation|nucleate RBC differentiation http://purl.obolibrary.org/obo/GO_0043363 CHEBI:138218 biolink:ChemicalSubstance 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138218 chebi_ph7_3 CHEBI:138217 biolink:ChemicalSubstance 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138217 chebi_ph7_3 CHEBI:138216 biolink:ChemicalSubstance 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138216 chebi_ph7_3 GO:0018359 biolink:BiologicalProcess protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine. RESID:AA0266 go-plus.json protein-haem P460 linkage via haem P460-bis-L-cysteine-L-tyrosine http://purl.obolibrary.org/obo/GO_0018359 GO:0018358 biolink:BiologicalProcess protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine. RESID:AA0133 go-plus.json http://purl.obolibrary.org/obo/GO_0018358 GO:0043369 biolink:BiologicalProcess CD4-positive or CD8-positive, alpha-beta T cell lineage commitment The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells. go-plus.json CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment|CD4-positive/CD8-positive, alpha-beta T cell lineage commitment http://purl.obolibrary.org/obo/GO_0043369 CHEBI:138219 biolink:ChemicalSubstance ent-atiserene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138219 chebi_ph7_3 GO:0033974 biolink:MolecularActivity nucleoside phosphoacylhydrolase activity Catalysis of the hydrolysis of mixed phospho-anhydride bonds. EC:3.6.1.24|MetaCyc:3.6.1.24-RXN go-plus.json nucleoside-5'-phosphoacylate acylhydrolase activity http://purl.obolibrary.org/obo/GO_0033974 GO:0018355 biolink:BiologicalProcess protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0018355 GO:0033973 biolink:MolecularActivity dCTP deaminase (dUMP-forming) activity Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+). MetaCyc:3.5.4.30-RXN|KEGG_REACTION:R07307|EC:3.5.4.30|RHEA:19205 go-plus.json dCTP aminohydrolase (dUMP-forming) activity http://purl.obolibrary.org/obo/GO_0033973 GO:0018354 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018354 GO:0033972 biolink:MolecularActivity proclavaminate amidinohydrolase activity Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea. EC:3.5.3.22|KEGG_REACTION:R05357|RHEA:17001|MetaCyc:3.5.3.22-RXN go-plus.json PAH|proclavaminic acid amidino hydrolase activity|proclavaminate amidino hydrolase activity http://purl.obolibrary.org/obo/GO_0033972 GO:0018357 biolink:BiologicalProcess protein-phycourobilin linkage via phycourobilin-bis-L-cysteine The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine. RESID:AA0260 go-plus.json http://purl.obolibrary.org/obo/GO_0018357 GO:0033971 biolink:MolecularActivity hydroxyisourate hydrolase activity Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+). EC:3.5.2.17|RHEA:23736|KEGG_REACTION:R06601|MetaCyc:3.5.2.17-RXN go-plus.json HIUHase activity|5-hydroxyisourate hydrolase activity|5-hydroxyisourate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0033971 GO:0018356 biolink:BiologicalProcess protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine. RESID:AA0258 go-plus.json http://purl.obolibrary.org/obo/GO_0018356 GO:0018351 biolink:BiologicalProcess peptidyl-cysteine esterification The addition of an ester group to a cysteine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018351 GO:0033970 biolink:MolecularActivity N-malonylurea hydrolase activity Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea. KEGG_REACTION:R07629|EC:3.5.1.95|RHEA:17361|MetaCyc:3.5.1.95-RXN go-plus.json ureidomalonase activity|3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity http://purl.obolibrary.org/obo/GO_0033970 GO:0018350 biolink:BiologicalProcess protein esterification The addition of an ester group to a protein amino acid. go-plus.json protein amino acid esterification http://purl.obolibrary.org/obo/GO_0018350 GO:0018353 biolink:BiologicalProcess protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine. RESID:AA0131 go-plus.json http://purl.obolibrary.org/obo/GO_0018353 CHEBI:138212 biolink:ChemicalSubstance 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138212 chebi_ph7_3 GO:0018352 biolink:BiologicalProcess protein-pyridoxal-5-phosphate linkage The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0018352 CHEBI:138211 biolink:ChemicalSubstance 1-octadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138211 chebi_ph7_3 GO:0033969 biolink:MolecularActivity gamma-glutamyl-gamma-aminobutyrate hydrolase activity Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate. KEGG_REACTION:R07419|RHEA:19737|EC:3.5.1.94|MetaCyc:RXN0-3942 go-plus.json gamma-glutamyl-GABA hydrolase activity|PuuD|4-(glutamylamino)butanoate amidohydrolase activity|YcjL http://purl.obolibrary.org/obo/GO_0033969 GO:0043371 biolink:BiologicalProcess negative regulation of CD4-positive, alpha-beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. go-plus.json negative regulation of CD4-positive, alpha beta T cell development|down-regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T lymphocyte differentiation|inhibition of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive T-cell differentiation|negative regulation of CD4-positive T-lymphocyte differentiation|down regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T-cell differentiation|downregulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043371 GO:0043370 biolink:BiologicalProcess regulation of CD4-positive, alpha-beta T cell differentiation Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. go-plus.json regulation of CD4-positive T-cell differentiation|regulation of CD4-positive T-lymphocyte differentiation|regulation of CD4-positive, alpha beta T cell differentiation|regulation of CD4-positive, alpha beta T-cell differentiation|regulation of CD4-positive, alpha beta T-lymphocyte differentiation|regulation of CD4-positive T lymphocyte differentiation|regulation of CD4-positive, alpha beta T cell development|regulation of CD4-positive, alpha beta T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043370 GO:0033968 biolink:MolecularActivity glutaryl-7-aminocephalosporanic-acid acylase activity Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate. EC:3.5.1.93|MetaCyc:3.5.1.93-RXN|RHEA:23508 go-plus.json GCA|cephalosporin acylase activity|glutaryl-7-aminocephalosporanic acid acylase activity|cephalosporin C acylase activity|CA|7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity|GA|GL-7-ACA acylase activity|glutaryl-7-ACA acylase activity|(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0033968 GO:0033967 biolink:BiologicalProcess box C/D RNA metabolic process The chemical reactions and pathways involving box C/D type small nucleolar RNA. go-plus.json box C/D sRNA metabolic process|box C/D snoRNA metabolic process http://purl.obolibrary.org/obo/GO_0033967 GO:0033966 biolink:MolecularActivity N-substituted formamide deformylase activity Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine. RHEA:12096|MetaCyc:3.5.1.91-RXN go-plus.json N-benzylformamide amidohydrolase activity|NfdA http://purl.obolibrary.org/obo/GO_0033966 GO:0033965 biolink:MolecularActivity aculeacin-A deacylase activity Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain. EC:3.5.1.70|MetaCyc:3.5.1.70-RXN go-plus.json aculeacin-A amidohydrolase activity|aculeacin A acylase activity http://purl.obolibrary.org/obo/GO_0033965 PR:000044637 biolink:Protein calcitonin receptor protein A rhodopsin-like G-protein coupled receptor that is a translation product of the human CALCR or CALCRL genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000044637 GO:0033964 biolink:MolecularActivity glycosphingolipid deacylase activity Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives. MetaCyc:3.5.1.69-RXN|EC:3.5.1.69 go-plus.json glycosphingolipid amidohydrolase activity|glycosphingolipid ceramide deacylase activity http://purl.obolibrary.org/obo/GO_0033964 GO:0043377 biolink:BiologicalProcess negative regulation of CD8-positive, alpha-beta T cell differentiation Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation. go-plus.json down regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T lymphocyte differentiation|downregulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha-beta T cell development|down-regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive T-cell differentiation|negative regulation of CD8-positive T-lymphocyte differentiation|negative regulation of CD8-positive, alpha beta T-cell differentiation|inhibition of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation|negative regulation of CD8-positive T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043377 GO:0043376 biolink:BiologicalProcess regulation of CD8-positive, alpha-beta T cell differentiation Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation. go-plus.json regulation of CD8-positive, alpha-beta T cell development|regulation of CD8-positive T-cell differentiation|regulation of CD8-positive T-lymphocyte differentiation|regulation of CD8-positive, alpha beta T-cell differentiation|regulation of CD8-positive, alpha beta T-lymphocyte differentiation|regulation of CD8-positive T lymphocyte differentiation|regulation of CD8-positive, alpha beta T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043376 GO:0043379 biolink:BiologicalProcess memory T cell differentiation The process in which a newly activated T cell acquires specialized features of a memory T cell. go-plus.json memory T-cell differentiation|memory T-lymphocyte differentiation|memory T cell development|memory T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043379 GO:0043378 biolink:BiologicalProcess positive regulation of CD8-positive, alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation. go-plus.json positive regulation of CD8-positive, alpha beta T lymphocyte differentiation|up regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell development|activation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T-cell differentiation|stimulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T-lymphocyte differentiation|positive regulation of CD8-positive, alpha beta T-cell differentiation|positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation|up-regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T lymphocyte differentiation|upregulation of CD8-positive, alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0043378 GO:0043373 biolink:BiologicalProcess CD4-positive, alpha-beta T cell lineage commitment The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell. go-plus.json CD4-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive, alpha-beta T-cell lineage commitment|CD4-positive, alpha-beta T lymphocyte lineage commitment http://purl.obolibrary.org/obo/GO_0043373 PR:000044631 biolink:Protein adrenoceptor protein A rhodopsin-like G-protein coupled receptor that is a translation product of the human ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, or ADRB3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000044631 GO:0043372 biolink:BiologicalProcess positive regulation of CD4-positive, alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation. go-plus.json stimulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T lymphocyte differentiation|up-regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive T-cell differentiation|positive regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive T-lymphocyte differentiation|positive regulation of CD4-positive, alpha beta T-cell differentiation|upregulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation|positive regulation of CD4-positive T lymphocyte differentiation|up regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T cell development|activation of CD4-positive, alpha beta T cell differentiation http://purl.obolibrary.org/obo/GO_0043372 PR:000044630 biolink:Protein corticotropin-releasing factor receptor A secretin-like G-protein coupled receptor that is a translation product of the human CRHR1 or CRHR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000044630 GO:0043375 biolink:BiologicalProcess CD8-positive, alpha-beta T cell lineage commitment The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell. go-plus.json CD8-positive, alpha-beta T cell fate commitment|CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD8-positive, alpha-beta T-cell lineage commitment|CD8-positive, alpha-beta T lymphocyte lineage commitment http://purl.obolibrary.org/obo/GO_0043375 GO:0043374 biolink:BiologicalProcess CD8-positive, alpha-beta T cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell. go-plus.json CD8-positive, alpha-beta T-cell differentiation|CD8-positive, alpha-beta T-lymphocyte differentiation|CD8-positive, alpha-beta T cell development|CD8-positive, alpha-beta T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043374 GO:0018329 biolink:BiologicalProcess obsolete enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine OBSOLETE. The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase. RESID:AA0227 go-plus.json http://purl.obolibrary.org/obo/GO_0018329 GO:0018326 biolink:BiologicalProcess obsolete enzyme active site formation via S-acetyl-L-cysteine OBSOLETE. The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine. RESID:AA0056 go-plus.json http://purl.obolibrary.org/obo/GO_0018326 GO:0018325 biolink:BiologicalProcess obsolete enzyme active site formation via S-phospho-L-cysteine OBSOLETE. The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine. RESID:AA0034 go-plus.json http://purl.obolibrary.org/obo/GO_0018325 GO:0018328 biolink:BiologicalProcess obsolete enzyme active site formation via 3'-phospho-L-histidine OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine). RESID:AA0036 go-plus.json http://purl.obolibrary.org/obo/GO_0018328 GO:0018327 biolink:BiologicalProcess obsolete enzyme active site formation via 1'-phospho-L-histidine OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine). RESID:AA0035 go-plus.json http://purl.obolibrary.org/obo/GO_0018327 GO:0033963 biolink:MolecularActivity cholesterol-5,6-oxide hydrolase activity Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol. MetaCyc:RXN-8651|MetaCyc:RXN-8650|EC:3.3.2.11 go-plus.json ChEH|5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity|cholesterol-epoxide hydrolase activity http://purl.obolibrary.org/obo/GO_0033963 GO:0018322 biolink:BiologicalProcess protein tyrosinylation The addition of a tyrosine molecule to a protein amino acid. go-plus.json protein amino acid tyrosinylation http://purl.obolibrary.org/obo/GO_0018322 GO:0018321 biolink:BiologicalProcess protein glucuronylation The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose. go-plus.json protein amino acid glucuronylation http://purl.obolibrary.org/obo/GO_0018321 GO:0033962 biolink:BiologicalProcess P-body assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. go-plus.json P body biogenesis|cytoplasmic mRNA processing body assembly|P body assembly http://purl.obolibrary.org/obo/GO_0033962 GO:0033961 biolink:MolecularActivity cis-stilbene-oxide hydrolase activity Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol. Reactome:R-HSA-5694077|EC:3.3.2.9|MetaCyc:3.3.2.9-RXN|RHEA:23900 go-plus.json microsomal epoxide hydratase activity|benzo[a]pyrene-4,5-oxide hydratase activity|arene-oxide hydratase activity|cis-epoxide hydrolase activity|epoxide hydrase activity|benzo(a)pyrene-4,5-epoxide hydratase activity|aryl epoxide hydrase activity|microsomal epoxide hydrase activity|microsomal epoxide hydrolase activity|epoxide hydratase activity|mEH http://purl.obolibrary.org/obo/GO_0033961 goslim_chembl GO:0018324 biolink:BiologicalProcess obsolete enzyme active site formation via L-cysteine sulfenic acid OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase. RESID:AA0205 go-plus.json enzyme active site formation via L-cysteine sulphenic acid http://purl.obolibrary.org/obo/GO_0018324 GO:0033960 biolink:MolecularActivity N-methyl nucleosidase activity Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose. RHEA:10880|MetaCyc:RXN-7597|KEGG_REACTION:R07918|EC:3.2.2.25 go-plus.json 7-methylxanthosine nucleosidase activity|N-methyl nucleoside hydrolase activity|7-methylxanthosine ribohydrolase activity|methylpurine nucleosidase activity|N-MeNase activity http://purl.obolibrary.org/obo/GO_0033960 GO:0018323 biolink:BiologicalProcess obsolete enzyme active site formation via L-cysteine sulfinic acid OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid. RESID:AA0262 go-plus.json enzyme active site formation via L-cysteine sulphinic acid http://purl.obolibrary.org/obo/GO_0018323 GO:0018320 biolink:BiologicalProcess obsolete enzyme active site formation via S-methyl-L-cysteine OBSOLETE. The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine. RESID:AA0234 go-plus.json http://purl.obolibrary.org/obo/GO_0018320 GO:0043380 biolink:BiologicalProcess regulation of memory T cell differentiation Any process that modulates the frequency, rate, or extent of memory T cell differentiation. go-plus.json regulation of memory T-cell differentiation|regulation of memory T-lymphocyte differentiation|regulation of memory T cell development|regulation of memory T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043380 GO:0033959 biolink:MolecularActivity deoxyribodipyrimidine endonucleosidase activity Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue. EC:3.2.2.17|MetaCyc:3.2.2.17-RXN go-plus.json deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity|PD-DNA glycosylase activity|endonuclease V activity|T4-induced UV endonuclease activity|pyrimidine dimer DNA glycosylase activity|deoxyribonucleate pyrimidine dimer glycosidase activity|pyrimidine dimer DNA-glycosylase activity http://purl.obolibrary.org/obo/GO_0033959 GO:0043382 biolink:BiologicalProcess positive regulation of memory T cell differentiation Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. go-plus.json up-regulation of memory T cell differentiation|positive regulation of memory T-cell differentiation|upregulation of memory T cell differentiation|positive regulation of memory T-lymphocyte differentiation|up regulation of memory T cell differentiation|positive regulation of memory T cell development|activation of memory T cell differentiation|stimulation of memory T cell differentiation|positive regulation of memory T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0043382 GO:0033958 biolink:MolecularActivity DNA-deoxyinosine glycosylase activity Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine. EC:3.2.2.15|MetaCyc:3.2.2.15-RXN go-plus.json hypoxanthine-DNA glycosylase activity|deoxyribonucleic acid glycosylase activity|DNA(hypoxanthine) glycohydrolase activity|DNA-deoxyinosine glycosidase activity|DNA-deoxyinosine deoxyribohydrolase activity http://purl.obolibrary.org/obo/GO_0033958 GO:0033957 biolink:MolecularActivity lambda-carrageenase activity Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S. EC:3.2.1.162|MetaCyc:3.2.1.162-RXN go-plus.json endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity http://purl.obolibrary.org/obo/GO_0033957 GO:0043381 biolink:BiologicalProcess negative regulation of memory T cell differentiation Any process that stops, prevents, or reduces the rate of memory T cell differentiation. go-plus.json negative regulation of memory T-cell differentiation|down regulation of memory T cell differentiation|downregulation of memory T cell differentiation|negative regulation of memory T-lymphocyte differentiation|negative regulation of memory T cell development|down-regulation of memory T cell differentiation|negative regulation of memory T lymphocyte differentiation|inhibition of memory T cell differentiation http://purl.obolibrary.org/obo/GO_0043381 PR:000044643 biolink:Protein complement peptide receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human C3AR1, C5AR1, or C5AR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. go-plus.json http://purl.obolibrary.org/obo/PR_000044643 GO:0033956 biolink:MolecularActivity beta-apiosyl-beta-glucosidase activity Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose. EC:3.2.1.161|MetaCyc:RXN-9156|RHEA:21488|MetaCyc:3.2.1.161-RXN go-plus.json isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity|isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity|furcatin hydrolase activity|7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity http://purl.obolibrary.org/obo/GO_0033956 GO:0033955 biolink:BiologicalProcess obsolete mitochondrial DNA inheritance OBSOLETE. The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission. go-plus.json mitochondrial chromosome segregation|mitochondrial DNA segregation http://purl.obolibrary.org/obo/GO_0033955 GO:0033954 biolink:MolecularActivity alpha-neoagaro-oligosaccharide hydrolase activity Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose. MetaCyc:3.2.1.159-RXN|EC:3.2.1.159 go-plus.json alpha-neoagarooligosaccharide hydrolase activity|alpha-neoagaro-oligosaccharide 3-glycohydrolase activity|alpha-NAOS hydrolase activity http://purl.obolibrary.org/obo/GO_0033954 GO:0033953 biolink:MolecularActivity alpha-agarase activity Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product. MetaCyc:3.2.1.158-RXN|EC:3.2.1.158 go-plus.json agarose 3-glycanohydrolase activity|agarase activity|agarase A33 activity http://purl.obolibrary.org/obo/GO_0033953 GO:0043388 biolink:BiologicalProcess positive regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). go-plus.json upregulation of DNA binding|up regulation of DNA binding|activation of DNA binding|stimulation of DNA binding|up-regulation of DNA binding http://purl.obolibrary.org/obo/GO_0043388 GO:0043387 biolink:BiologicalProcess mycotoxin catabolic process The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus. go-plus.json mycotoxin degradation|mycotoxin breakdown|mycotoxin catabolism http://purl.obolibrary.org/obo/GO_0043387 GO:0043389 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043389 GO:0043384 biolink:CellularComponent pre-T cell receptor complex A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins. go-plus.json pre-T-lymphocyte receptor complex|pre-TCR complex|pre-T-cell receptor complex|pre-T lymphocyte receptor complex http://purl.obolibrary.org/obo/GO_0043384 GO:0043383 biolink:BiologicalProcess negative T cell selection The process of elimination of immature T cells which react strongly with self-antigens. go-plus.json negative T-lymphocyte selection|negative T lymphocyte selection|negative T-cell selection http://purl.obolibrary.org/obo/GO_0043383 GO:0043386 biolink:BiologicalProcess mycotoxin biosynthetic process The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus. go-plus.json mycotoxin anabolism|mycotoxin biosynthesis|mycotoxin synthesis|mycotoxin formation http://purl.obolibrary.org/obo/GO_0043386 GO:0043385 biolink:BiologicalProcess mycotoxin metabolic process The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus. go-plus.json mycotoxin metabolism http://purl.obolibrary.org/obo/GO_0043385 GO:0018337 biolink:BiologicalProcess obsolete enzyme active site formation via L-2',4',5'-topaquinone OBSOLETE. (Was not defined before being made obsolete). go-plus.json enzyme active site formation via L-2',4',5'-topaquinone http://purl.obolibrary.org/obo/GO_0018337 GO:0018336 biolink:BiologicalProcess peptidyl-tyrosine hydroxylation The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine. go-plus.json http://purl.obolibrary.org/obo/GO_0018336 GO:0018339 biolink:BiologicalProcess peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12. RESID:AA0232 go-plus.json peptidyl-L-beta-methylthioaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-L-beta-methylthioaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-L-beta-methylthioaspartic acid formation from peptidyl-aspartic acid|peptidyl-aspartic acid methylthiolation http://purl.obolibrary.org/obo/GO_0018339 GO:0018338 biolink:BiologicalProcess obsolete protein amino acid cinnamylation OBSOLETE. The modification of a protein amino acid by cinnamylation. go-plus.json protein amino acid cinnamylation http://purl.obolibrary.org/obo/GO_0018338 GO:0018333 biolink:BiologicalProcess obsolete enzyme active site formation via O-phospho-L-threonine OBSOLETE. The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine. RESID:AA0038 go-plus.json http://purl.obolibrary.org/obo/GO_0018333 GO:0033952 biolink:MolecularActivity iota-carrageenase activity Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans. MetaCyc:3.2.1.157-RXN|EC:3.2.1.157 go-plus.json iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity http://purl.obolibrary.org/obo/GO_0033952 GO:0018332 biolink:BiologicalProcess obsolete enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine OBSOLETE. The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I. RESID:AA0267 go-plus.json http://purl.obolibrary.org/obo/GO_0018332 GO:0033951 biolink:MolecularActivity oligosaccharide reducing-end xylanase activity Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides. MetaCyc:3.2.1.156-RXN|EC:3.2.1.156 go-plus.json Rex|reducing end xylose-releasing exo-oligoxylanase activity|beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity http://purl.obolibrary.org/obo/GO_0033951 GO:0033950 biolink:MolecularActivity xyloglucan-specific exo-beta-1,4-glucanase activity Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan. MetaCyc:3.2.1.155-RXN|EC:3.2.1.155 go-plus.json [(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity|Cel74A http://purl.obolibrary.org/obo/GO_0033950 GO:0018335 biolink:BiologicalProcess protein succinylation The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue. go-plus.json protein amino acid succinylation http://purl.obolibrary.org/obo/GO_0018335 GO:0018334 biolink:BiologicalProcess obsolete enzyme active site formation via O4'-phospho-L-tyrosine OBSOLETE. The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine. RESID:AA0039 go-plus.json http://purl.obolibrary.org/obo/GO_0018334 GO:0018331 biolink:BiologicalProcess obsolete enzyme active site formation via O-phospho-L-serine OBSOLETE. The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine. RESID:AA0037 go-plus.json http://purl.obolibrary.org/obo/GO_0018331 GO:0018330 biolink:BiologicalProcess obsolete enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine OBSOLETE. The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme. RESID:AA0228 go-plus.json http://purl.obolibrary.org/obo/GO_0018330 GO:0033949 biolink:MolecularActivity fructan beta-(2,6)-fructosidase activity Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans. MetaCyc:3.2.1.154-RXN|EC:3.2.1.154 go-plus.json beta-(2,6)-fructan exohydrolase activity|beta-(2,6)-D-fructan fructohydrolase activity|6-FEH http://purl.obolibrary.org/obo/GO_0033949 GO:0043391 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043391 GO:0033948 biolink:MolecularActivity fructan beta-(2,1)-fructosidase activity Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans. MetaCyc:3.2.1.153-RXN|EC:3.2.1.153 go-plus.json beta-(2,1)-D-fructan fructohydrolase activity|1-fructan exohydrolase activity|beta-(2,1)-linkage-specific fructan-beta-fructosidase activity|1-FEH II|1-FEH w2|1-FEH w1|beta-(2,1)-fructan exohydrolase activity http://purl.obolibrary.org/obo/GO_0033948 GO:0043390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043390 GO:0043393 biolink:BiologicalProcess regulation of protein binding Any process that modulates the frequency, rate or extent of protein binding. go-plus.json http://purl.obolibrary.org/obo/GO_0043393 GO:0033947 biolink:MolecularActivity mannosylglycoprotein endo-beta-mannosidase activity Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences. MetaCyc:3.2.1.152-RXN|EC:3.2.1.152 go-plus.json endo-beta-mannosidase activity http://purl.obolibrary.org/obo/GO_0033947 GO:0043392 biolink:BiologicalProcess negative regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). go-plus.json inhibition of DNA binding|down regulation of DNA binding|downregulation of DNA binding|down-regulation of DNA binding http://purl.obolibrary.org/obo/GO_0043392 GO:0033946 biolink:MolecularActivity xyloglucan-specific endo-beta-1,4-glucanase activity Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan. MetaCyc:3.2.1.151-RXN|EC:3.2.1.151 go-plus.json xyloglucanase activity|XEG|1,4-beta-D-glucan glucanohydrolase activity|XH|xyloglucan endo-beta-1,4-glucanase activity|xyloglucanendohydrolase activity|[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity http://purl.obolibrary.org/obo/GO_0033946 GO:0008989 biolink:MolecularActivity rRNA (guanine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine. MetaCyc:RRNA-GUANINE-N1--METHYLTRANSFERASE-RXN go-plus.json ribosomal ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008989 GO:0033945 biolink:MolecularActivity oligoxyloglucan reducing-end-specific cellobiohydrolase activity Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted. MetaCyc:3.2.1.150-RXN|EC:3.2.1.150 go-plus.json oligoxyloglucan reducing end-specific cellobiohydrolase activity|oligoxyloglucan reducing-end cellobiohydrolase activity http://purl.obolibrary.org/obo/GO_0033945 GO:0033944 biolink:MolecularActivity beta-galactofuranosidase activity Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose. MetaCyc:3.2.1.146-RXN|EC:3.2.1.146 go-plus.json exo-beta-galactofuranosidase activity|beta-D-galactofuranosidase activity|beta-D-galactofuranoside hydrolase activity|exo-beta-D-galactofuranosidase activity http://purl.obolibrary.org/obo/GO_0033944 GO:0008988 biolink:MolecularActivity rRNA (adenine-N6-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine. go-plus.json gene ksgA methyltransferase|ribonucleic acid-adenine (N(6)) methylase activity|ribosomal ribonucleate adenine 6-methyltransferase activity|ribonucleic acid-adenine (N6) methylase activity|S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity|ErmC 23S rRNA methyltransferase http://purl.obolibrary.org/obo/GO_0008988 GO:0033943 biolink:MolecularActivity galactan 1,3-beta-galactosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans. MetaCyc:3.2.1.145-RXN|EC:3.2.1.145 go-plus.json galactan (1,3)-beta-D-galactosidase activity|galactan (1->3)-beta-D-galactosidase activity http://purl.obolibrary.org/obo/GO_0033943 GO:0008987 biolink:MolecularActivity quinolinate synthetase A activity Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate. MetaCyc:QUINOLINATE-SYNTHA-RXN|RHEA:25888 go-plus.json http://purl.obolibrary.org/obo/GO_0008987 GO:0008986 biolink:MolecularActivity pyruvate, water dikinase activity Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate. EC:2.7.9.2|MetaCyc:PEPSYNTH-RXN|KEGG_REACTION:R00199|RHEA:11364 go-plus.json PEP synthetase activity|pyruvate-water dikinase (phosphorylating)|phosphoenolpyruvate synthase activity|ATP:pyruvate, water phosphotransferase activity|phoephoenolpyruvate synthetase activity|phosphoenolpyruvic synthase activity|pyruvate,water dikinase activity|water pyruvate dikinase activity|PEP synthase activity|phosphopyruvate synthetase activity http://purl.obolibrary.org/obo/GO_0008986 GO:0033942 biolink:MolecularActivity 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan. MetaCyc:3.2.1.141-RXN|EC:3.2.1.141 go-plus.json 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|maltooligosyl trehalose trehalohydrolase activity|4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|malto-oligosyltrehalose trehalohydrolase activity http://purl.obolibrary.org/obo/GO_0033942 GO:0008985 biolink:MolecularActivity obsolete pyruvate dehydrogenase (cytochrome) activity OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1. go-plus.json pyruvate:ferricytochrome-b1 oxidoreductase activity|pyruvate:ubiquinone-8-oxidoreductase activity|pyruvic (cytochrome b1) dehydrogenase activity|pyruvate dehydrogenase (cytochrome) activity http://purl.obolibrary.org/obo/GO_0008985 GO:0043399 biolink:MolecularActivity tRNA A64-2'-O-ribosylphosphate transferase activity Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA. go-plus.json initiator tRNA phosphoribosyl-transferase activity http://purl.obolibrary.org/obo/GO_0043399 GO:0008984 biolink:MolecularActivity protein-glutamate methylesterase activity Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol. RESID:AA0072|MetaCyc:MCPMETEST-RXN|EC:3.1.1.61|RHEA:23236 go-plus.json methyl-accepting chemotaxis protein methyl-esterase activity|protein-L-glutamate-5-O-methyl-ester acylhydrolase activity|CheB methylesterase activity|protein-L-glutamate-O5-methyl-ester acylhydrolase activity|methylesterase CheB activity|chemotaxis-specific methylesterase activity http://purl.obolibrary.org/obo/GO_0008984 GO:0043398 biolink:MolecularActivity HLH domain binding Binding to a Helix Loop Helix domain, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization. go-plus.json http://purl.obolibrary.org/obo/GO_0043398 GO:0008983 biolink:MolecularActivity protein-glutamate O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester. MetaCyc:CHER-RXN|RESID:AA0072|EC:2.1.1.80|RHEA:24452 go-plus.json protein O-methyltransferase activity|protein carboxyl-methylase activity|protein carboxymethylase activity|protein(carboxyl)methyltransferase activity|protein carboxylmethyltransferase II|MCP methyltransferase II|S-adenosylmethionine-glutamyl methyltransferase activity|S-adenosylmethionine:protein-carboxyl O-methyltransferase activity|S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity|methyl-accepting chemotaxis protein methyltransferase II|MCP methyltransferase I|protein carboxymethyltransferase activity|protein carboxyl-O-methyltransferase activity|protein methylase II|protein(aspartate)methyltransferase activity|methyl-accepting chemotaxis protein O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008983 GO:0008982 biolink:MolecularActivity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. MetaCyc:2.7.1.69-RXN|EC:2.7.1.69 go-plus.json PEP--sugar phosphotransferase enzyme II activity|phosphotransfer-driven group translocator|protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity|PTS transporter|phosphohistidinoprotein-hexose phosphotransferase activity|protein-Npi-phosphohistidine-sugar phosphotransferase activity|gene bglC RNA formation factors|protein, specific or class, gene bglC|PTS permease activity|PEP-dependent phosphotransferase enzyme II|group translocator activity|phosphoprotein factor-hexose phosophotransferase activity|protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity|gene glC proteins|phosphoenolpyruvate-sugar phosphotransferase enzyme II|protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity|protein-Np-phosphohistidine-sugar phosphotransferase activity|enzyme II of the phosphotransferase system|ribonucleic acid formation factor, gene glC|sucrose phosphotransferase system II|phosphotransferase, phosphohistidinoprotein-hexose activity|phosphohistidinoprotein-hexose phosphoribosyltransferase activity|enzyme IIl4ac http://purl.obolibrary.org/obo/GO_0008982 GO:0008981 biolink:MolecularActivity obsolete protease IV activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json protease IV activity http://purl.obolibrary.org/obo/GO_0008981 GO:0043395 biolink:MolecularActivity heparan sulfate proteoglycan binding Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit. go-plus.json heparin proteoglycan binding http://purl.obolibrary.org/obo/GO_0043395 GO:0008980 biolink:MolecularActivity propionate kinase activity Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate. EC:2.7.2.15|RHEA:23148 go-plus.json propanoate kinase activity|ATP:propanoate phosphotransferase activity|PduW|TdcD http://purl.obolibrary.org/obo/GO_0008980 GO:0043394 biolink:MolecularActivity proteoglycan binding Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans. go-plus.json http://purl.obolibrary.org/obo/GO_0043394 GO:0043397 biolink:BiologicalProcess regulation of corticotropin-releasing hormone secretion Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion. go-plus.json regulation of CRH secretion|regulation of CRF secretion|regulation of corticotropin-releasing factor secretion http://purl.obolibrary.org/obo/GO_0043397 GO:0043396 biolink:BiologicalProcess corticotropin-releasing hormone secretion The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle. go-plus.json CRH secretion|CRF secretion|corticotropin-releasing factor secretion http://purl.obolibrary.org/obo/GO_0043396 CHEBI:58794 biolink:ChemicalSubstance (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58794 chebi_ph7_3 GO:0018308 biolink:BiologicalProcess obsolete enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase. go-plus.json enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine http://purl.obolibrary.org/obo/GO_0018308 GO:0018307 biolink:BiologicalProcess obsolete enzyme active site formation OBSOLETE. The modification of part of an enzyme to form the active site. go-plus.json http://purl.obolibrary.org/obo/GO_0018307 CHEBI:58793 biolink:ChemicalSubstance 2-O-sinapoyl-D-glucarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58793 chebi_ph7_3 CHEBI:58792 biolink:ChemicalSubstance 2-azaniumyl-2-deoxyisochorismate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58792 chebi_ph7_3 GO:0018309 biolink:BiologicalProcess protein-FMN linkage The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN). go-plus.json http://purl.obolibrary.org/obo/GO_0018309 GO:0018304 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide. RESID:AA0286 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulphide http://purl.obolibrary.org/obo/GO_0018304 CHEBI:58790 biolink:ChemicalSubstance 3-(1-carboxylatovinyloxy)anthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58790 chebi_ph7_3 GO:0018303 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide. RESID:AA0285 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulphide http://purl.obolibrary.org/obo/GO_0018303 GO:0018306 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide. RESID:AA0289 go-plus.json iron incorporation into iron-sulphur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulphide http://purl.obolibrary.org/obo/GO_0018306 GO:0018305 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide. RESID:AA0288 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulphide http://purl.obolibrary.org/obo/GO_0018305 GO:0018300 biolink:BiologicalProcess obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide. go-plus.json iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl hexairon hexasulphide|iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide http://purl.obolibrary.org/obo/GO_0018300 GO:0033941 biolink:MolecularActivity mannan exo-1,2-1,6-alpha-mannosidase activity Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose. MetaCyc:3.2.1.137-RXN|EC:3.2.1.137 go-plus.json exo-1,2-1,6-alpha-mannosidase activity|1,2-1,6-alpha-D-mannan D-mannohydrolase activity http://purl.obolibrary.org/obo/GO_0033941 GO:0033940 biolink:MolecularActivity glucuronoarabinoxylan endo-1,4-beta-xylanase activity Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans. MetaCyc:3.2.1.136-RXN|EC:3.2.1.136 go-plus.json glucuronoxylan xylohydrolase activity|glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity|glucuronoxylan xylanohydrolase activity|feraxan endoxylanase activity|glucuronoxylanase activity|feraxanase activity|endoarabinoxylanase activity http://purl.obolibrary.org/obo/GO_0033940 GO:0018302 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide. RESID:AA0284 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulphide http://purl.obolibrary.org/obo/GO_0018302 GO:0018301 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon. RESID:AA0268 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-cysteine persulphido-bis-L-glutamato-L-histidino tetrairon http://purl.obolibrary.org/obo/GO_0018301 CHEBI:58799 biolink:ChemicalSubstance (2S)-2-{[(1R)-1-carboxylatoethyl]azaniumyl}pentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58799 chebi_ph7_3 CHEBI:58798 biolink:ChemicalSubstance N-(6-aminohexanoyl)-6-aminohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58798 chebi_ph7_3 CHEBI:2076 biolink:ChemicalSubstance 5-hydroxykynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_2076 CHEBI:58797 biolink:ChemicalSubstance (S,S)-9,10-dihydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58797 chebi_ph7_3 CHEBI:58796 biolink:ChemicalSubstance (9S,10S)-10-hydroxy-9-(phosphonatooxy)octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58796 chebi_ph7_3 CHEBI:58795 biolink:ChemicalSubstance 1-hydroxy-5-(methylthio)-3-oxopent-1-en-2-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58795 GO:0033938 biolink:MolecularActivity 1,6-alpha-L-fucosidase activity Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin. MetaCyc:3.2.1.127-RXN|EC:3.2.1.127 go-plus.json 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity http://purl.obolibrary.org/obo/GO_0033938 GO:0033937 biolink:MolecularActivity 3-deoxy-2-octulosonidase activity Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides. EC:3.2.1.124|MetaCyc:3.2.1.124-RXN go-plus.json octulofuranosylono hydrolase activity|octulosylono hydrolase activity|octulopyranosylonohydrolase activity|2-keto-3-deoxyoctonate hydrolase activity|capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity http://purl.obolibrary.org/obo/GO_0033937 GO:0033936 biolink:MolecularActivity polymannuronate hydrolase activity Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate. EC:3.2.1.121|MetaCyc:3.2.1.121-RXN go-plus.json polymannuronic acid polymerase activity|poly(mannuronide) mannuronohydrolase activity http://purl.obolibrary.org/obo/GO_0033936 GO:0033935 biolink:MolecularActivity oligoxyloglucan beta-glycosidase activity Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends. EC:3.2.1.120|MetaCyc:3.2.1.120-RXN go-plus.json oligoxyloglucan xyloglucohydrolase activity|oligoxyloglucan hydrolase activity|isoprimeverose-producing oligoxyloglucan hydrolase activity http://purl.obolibrary.org/obo/GO_0033935 GO:0033934 biolink:MolecularActivity glucan 1,4-alpha-maltotriohydrolase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends. MetaCyc:3.2.1.116-RXN|EC:3.2.1.116 go-plus.json 1,4-alpha-D-glucan maltotriohydrolase activity|maltotriohydrolase activity|exo-maltotriohydrolase activity http://purl.obolibrary.org/obo/GO_0033934 GO:0008999 biolink:MolecularActivity ribosomal-protein-alanine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine. MetaCyc:2.3.1.128-RXN|EC:2.3.1.267 go-plus.json acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity|ribosomal protein S18 acetyltransferase activity http://purl.obolibrary.org/obo/GO_0008999 GO:0033933 biolink:MolecularActivity branched-dextran exo-1,2-alpha-glucosidase activity Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose. MetaCyc:3.2.1.115-RXN|EC:3.2.1.115 go-plus.json dextran alpha-1,2 debranching enzyme|dextran 1,2-alpha-glucosidase activity|1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity http://purl.obolibrary.org/obo/GO_0033933 GO:0008998 biolink:MolecularActivity ribonucleoside-triphosphate reductase activity Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin. RHEA:12701|EC:1.17.4.2|MetaCyc:1.17.4.2-RXN go-plus.json 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity|2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|ribonucleotide reductase activity http://purl.obolibrary.org/obo/GO_0008998 GO:0033932 biolink:MolecularActivity 1,3-alpha-L-fucosidase activity Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins. EC:3.2.1.111|MetaCyc:3.2.1.111-RXN go-plus.json 3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity|almond emulsin fucosidase I activity http://purl.obolibrary.org/obo/GO_0033932 GO:0008997 biolink:MolecularActivity ribonuclease R activity Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides. EC:3.1.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0008997 GO:0033931 biolink:MolecularActivity endogalactosaminidase activity Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine). MetaCyc:3.2.1.109-RXN|EC:3.2.1.109 go-plus.json galactosaminoglycan glycanohydrolase activity http://purl.obolibrary.org/obo/GO_0033931 GO:0008996 biolink:MolecularActivity ribonuclease G activity Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group. go-plus.json http://purl.obolibrary.org/obo/GO_0008996 GO:0008995 biolink:MolecularActivity ribonuclease E activity Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group. MetaCyc:3.1.26.12-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008995 GO:0008994 biolink:MolecularActivity rhamnulose-1-phosphate aldolase activity Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde. MetaCyc:RHAMNULPALDOL-RXN|RHEA:19689|EC:4.1.2.19 go-plus.json L-rhamnulose 1-phosphate aldolase activity|rhamnulose phosphate aldolase activity|L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|L-rhamnulose-1-phosphate lactaldehyde-lyase activity|L-rhamnulose-phosphate aldolase activity http://purl.obolibrary.org/obo/GO_0008994 OBO:GOCHE_35222 biolink:OntologyClass substance with inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35222 3_STAR GO:0008993 biolink:MolecularActivity rhamnulokinase activity Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate. RHEA:20117|MetaCyc:RHAMNULOKIN-RXN|EC:2.7.1.5 go-plus.json RhuK|L-rhamnulose kinase activity|rhamnulose kinase activity|ATP:L-rhamnulose 1-phosphotransferase activity|L-rhamnulokinase activity|rhamnulokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0008993 CHEBI:44147 biolink:ChemicalSubstance menaquinone-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_44147 chebi_ph7_3 OBO:GOCHE_35221 biolink:OntologyClass substance with antimetabolite role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35221 3_STAR GO:0008992 biolink:MolecularActivity obsolete repressor LexA activity OBSOLETE. Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA. go-plus.json LexA repressor|repressor lexA|repressor LexA activity http://purl.obolibrary.org/obo/GO_0008992 GO:0008991 biolink:MolecularActivity obsolete serine-type signal peptidase activity OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism. go-plus.json serine-type signal peptidase activity http://purl.obolibrary.org/obo/GO_0008991 GO:0008990 biolink:MolecularActivity rRNA (guanine-N2-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine. MetaCyc:RRNA-GUANINE-N2--METHYLTRANSFERASE-RXN|EC:2.1.1.52 go-plus.json S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity|ribosomal ribonucleate guanine-2-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008990 GO:0033939 biolink:MolecularActivity xylan alpha-1,2-glucuronosidase activity Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans. MetaCyc:3.2.1.131-RXN|EC:3.2.1.131 go-plus.json xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity|alpha-(1->2)-glucuronidase activity|1,2-alpha-glucuronidase activity http://purl.obolibrary.org/obo/GO_0033939 CHEBI:58783 biolink:ChemicalSubstance 2-hydroxy-3-methylacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58783 chebi_ph7_3 GO:0018319 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018319 GO:0018318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018318 CHEBI:58782 biolink:ChemicalSubstance D-dopachrome(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58782 chebi_ph7_3 CHEBI:58781 biolink:ChemicalSubstance (4R)-2-acetyl-4-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-4-methyl-3-oxocyclohexa-1,5-dien-1-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58781 chebi_ph7_3 PR:000030035 biolink:Protein G-protein coupled receptor A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit. go-plus.json seven-transmembrane receptor|7TM receptor|fam:GPCR http://purl.obolibrary.org/obo/PR_000030035 CHEBI:58780 biolink:ChemicalSubstance 2,6-dihydroxynicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58780 chebi_ph7_3 GO:0018315 biolink:BiologicalProcess molybdenum incorporation into molybdenum-molybdopterin complex The incorporation of molybdenum into a molybdenum-molybdopterin complex. go-plus.json molybdenum incorporation into metallo-pterin complex http://purl.obolibrary.org/obo/GO_0018315 GO:0018314 biolink:BiologicalProcess obsolete protein-pyrroloquinoline-quinone linkage OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine. go-plus.json protein-pyrroloquinoline-quinone linkage http://purl.obolibrary.org/obo/GO_0018314 GO:0018317 biolink:BiologicalProcess protein C-linked glycosylation via tryptophan The glycosylation of a carbon atom of a peptidyl-tryptophan residue. go-plus.json protein amino acid C-linked glycosylation via tryptophan http://purl.obolibrary.org/obo/GO_0018317 GO:0018316 biolink:BiologicalProcess peptide cross-linking via L-cystine The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain. RESID:AA0025 go-plus.json http://purl.obolibrary.org/obo/GO_0018316 GO:0018311 biolink:BiologicalProcess peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine. RESID:AA0236 go-plus.json peptidyl-N4-hydroxymethyl-L-asparagine formation from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine synthesis from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine anabolism from peptidyl-asparagine http://purl.obolibrary.org/obo/GO_0018311 GO:0033930 biolink:MolecularActivity keratan-sulfate endo-1,4-beta-galactosidase activity Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate. MetaCyc:3.2.1.103-RXN|EC:3.2.1.103 go-plus.json endo-beta-galactosidase activity|keratanase activity|keratan-sulfate 1,4-beta-D-galactanohydrolase activity|keratan sulfate endogalactosidase activity http://purl.obolibrary.org/obo/GO_0033930 CHEBI:2082 biolink:ChemicalSubstance 5-hydroxyxanthotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_2082 GO:0018310 biolink:BiologicalProcess protein-FMN linkage via S-(6-FMN)-L-cysteine The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine. RESID:AA0220 go-plus.json http://purl.obolibrary.org/obo/GO_0018310 GO:0018313 biolink:BiologicalProcess peptide cross-linking via L-alanyl-5-imidazolinone glycine The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water. RESID:AA0187 go-plus.json http://purl.obolibrary.org/obo/GO_0018313 GO:0018312 biolink:BiologicalProcess peptidyl-serine ADP-ribosylation The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine. RESID:AA0237 go-plus.json http://purl.obolibrary.org/obo/GO_0018312 CHEBI:58787 biolink:ChemicalSubstance cis-3,4-didehydroadipoyl-CoA semialdehyde(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58787 chebi_ph7_3 CHEBI:58786 biolink:ChemicalSubstance cis-3,4-didehydroadipoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58786 chebi_ph7_3 CHEBI:58785 biolink:ChemicalSubstance 2,3-dihydroxy-2,3-dihydrobenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58785 chebi_ph7_3 CHEBI:58784 biolink:ChemicalSubstance 2-hydroxy-3-methylhexadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58784 chebi_ph7_3 CHEBI:83739 biolink:ChemicalSubstance ferroheme c di-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83739 chebi_ph7_3 GO:0102232 biolink:MolecularActivity acrolein reductase activity Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP. MetaCyc:RXN-12281 go-plus.json http://purl.obolibrary.org/obo/GO_0102232 CHEBI:83738 biolink:ChemicalSubstance 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydroinden-4-yl]propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83738 chebi_ph7_3 GO:0102234 biolink:MolecularActivity but-1-en-3-one reductase activity Catalysis of the reaction: buten-2-one + NADPH + H+ <=> butan-2-one + NADP. MetaCyc:RXN-12293 go-plus.json http://purl.obolibrary.org/obo/GO_0102234 CHEBI:83736 biolink:ChemicalSubstance 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1,5-dioxo-octahydroinden-4-yl]propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83736 chebi_ph7_3 GO:0102233 biolink:MolecularActivity crotonaldehyde redutase activity Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP. MetaCyc:RXN-12292 go-plus.json http://purl.obolibrary.org/obo/GO_0102233 GO:0102236 biolink:MolecularActivity trans-4-hexen-3-one reductase activity Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP. MetaCyc:RXN-12296 go-plus.json http://purl.obolibrary.org/obo/GO_0102236 GO:0102235 biolink:MolecularActivity 1-penten-3-one reductase activity Catalysis of the reaction: 1-penten-3-one + NADPH + H+ <=> 1-pentan-3-one + NADP. MetaCyc:RXN-12295 go-plus.json http://purl.obolibrary.org/obo/GO_0102235 GO:0102238 biolink:MolecularActivity geraniol kinase activity (ATP-dependent) activity Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+. MetaCyc:RXN-12307 go-plus.json http://purl.obolibrary.org/obo/GO_0102238 GO:0102237 biolink:MolecularActivity ATP:farnesol kinase activity Catalysis of the reaction: 2-trans,-6-trans-farnesol + ATP = 2-trans,-6-trans-farnesyl monophosphate + ADP + H+. MetaCyc:RXN-12304|RHEA:61656 go-plus.json ATP-dependent farnesol kinase activity http://purl.obolibrary.org/obo/GO_0102237 PR:000019642 biolink:Protein dystroglycan proteolytic cleavage product A dystroglycan that has been processed by proteolytic cleavage. go-plus.json DAG1/ClvPrd http://purl.obolibrary.org/obo/PR_000019642 GO:0102241 biolink:MolecularActivity soyasaponin III rhamnosyltransferase activity Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I. RHEA:31491|EC:2.4.1.273|MetaCyc:RXN-12320 go-plus.json http://purl.obolibrary.org/obo/GO_0102241 GO:0102240 biolink:MolecularActivity soyasapogenol B glucuronide galactosyltransferase activity Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III. RHEA:31487|MetaCyc:RXN-12319|EC:2.4.1.272 go-plus.json http://purl.obolibrary.org/obo/GO_0102240 GO:0102243 biolink:MolecularActivity ATP:geranylgeraniol phosphotransferase activity Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP. RHEA:61660|EC:2.7.1.216|MetaCyc:RXN-12325 go-plus.json http://purl.obolibrary.org/obo/GO_0102243 GO:0102245 biolink:MolecularActivity lupan-3beta,20-diol synthase activity Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O. RHEA:31351|EC:4.2.1.128|MetaCyc:RXN-12338 go-plus.json http://purl.obolibrary.org/obo/GO_0102245 CHEBI:83746 biolink:ChemicalSubstance 3-ketocholest-4-en-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_83746 chebi_ph7_3 GO:0102244 biolink:MolecularActivity 3-aminopropanal dehydrogenase activity Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine + NADH. MetaCyc:RXN-12332 go-plus.json http://purl.obolibrary.org/obo/GO_0102244 GO:0102247 biolink:MolecularActivity malonyl-malonyl acyl carrier protein-condensing enzyme activity Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein]. MetaCyc:RXN-12361 go-plus.json http://purl.obolibrary.org/obo/GO_0102247 CHEBI:83745 biolink:ChemicalSubstance validamycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_83745 GO:0102246 biolink:MolecularActivity 6-amino-6-deoxyfutalosine hydrolase activity Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine. EC:3.2.2.30|RHEA:33079|MetaCyc:RXN-12346 go-plus.json http://purl.obolibrary.org/obo/GO_0102246 GO:0102249 biolink:MolecularActivity phosphatidylcholine:diacylglycerol cholinephosphotransferase activity Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine. MetaCyc:RXN-12386 go-plus.json http://purl.obolibrary.org/obo/GO_0102249 GO:0102248 biolink:MolecularActivity diacylglycerol transacylase activity Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride. MetaCyc:RXN-12383 go-plus.json http://purl.obolibrary.org/obo/GO_0102248 CHEBI:138290 biolink:ChemicalSubstance 2-hydroxyoctanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138290 chebi_ph7_3 GO:0102250 biolink:MolecularActivity linear malto-oligosaccharide phosphorylase activity Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide. EC:2.4.1.1|MetaCyc:RXN-12392 go-plus.json http://purl.obolibrary.org/obo/GO_0102250 GO:0102252 biolink:MolecularActivity cellulose 1,4-beta-cellobiosidase activity (reducing end) Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains. EC:3.2.1.176|MetaCyc:RXN-12420 go-plus.json http://purl.obolibrary.org/obo/GO_0102252 CHEBI:138294 biolink:ChemicalSubstance N(epsilon)-(5'-guanylyl)-L-lysine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138294 chebi_ph7_3 GO:0102251 biolink:MolecularActivity all-trans-beta-apo-10'-carotenal cleavage oxygenase activity Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial. MetaCyc:RXN-12393|EC:1.13.11.70|RHEA:26401 go-plus.json http://purl.obolibrary.org/obo/GO_0102251 CHEBI:138293 biolink:ChemicalSubstance bis(hydroperoxy)icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138293 GO:0102254 biolink:MolecularActivity neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose. EC:3.2.1.159|MetaCyc:RXN-12427 go-plus.json http://purl.obolibrary.org/obo/GO_0102254 CHEBI:138292 biolink:ChemicalSubstance 2-hydroxydecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138292 chebi_ph7_3 GO:0102253 biolink:MolecularActivity neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside. EC:3.2.1.159|MetaCyc:RXN-12426 go-plus.json http://purl.obolibrary.org/obo/GO_0102253 CHEBI:138291 biolink:ChemicalSubstance (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138291 GO:0102256 biolink:MolecularActivity neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose. EC:3.2.1.159|MetaCyc:RXN-12429 go-plus.json http://purl.obolibrary.org/obo/GO_0102256 CHEBI:83757 biolink:ChemicalSubstance EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_83757 GO:0102255 biolink:MolecularActivity neo-lambda-carrahexaose hydrolase activity Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose. MetaCyc:RXN-12428|EC:3.2.1.162 go-plus.json http://purl.obolibrary.org/obo/GO_0102255 GO:0102258 biolink:MolecularActivity 1,3-diacylglycerol acylhydrolase activity Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid. MetaCyc:RXN-12433 go-plus.json http://purl.obolibrary.org/obo/GO_0102258 GO:0102257 biolink:MolecularActivity 1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O <=> 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+. MetaCyc:RXN-12430 go-plus.json http://purl.obolibrary.org/obo/GO_0102257 GO:0102259 biolink:MolecularActivity 1,2-diacylglycerol acylhydrolase activity Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid. MetaCyc:RXN-12434 go-plus.json http://purl.obolibrary.org/obo/GO_0102259 CHEBI:138286 biolink:ChemicalSubstance N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138286 chebi_ph7_3 CHEBI:138284 biolink:ChemicalSubstance 5'-end ribonucleoside residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138284 chebi_ph7_3 CHEBI:138288 biolink:ChemicalSubstance 5'-end purine ribonucleotide 5'-triphosphate(4-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138288 chebi_ph7_3 GO:0102261 biolink:MolecularActivity 8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420. EC:1.5.1.40|RHEA:31363|MetaCyc:RXN-12450 go-plus.json http://purl.obolibrary.org/obo/GO_0102261 GO:0102260 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102260 GO:0102263 biolink:MolecularActivity tRNA-dihydrouridine17 synthase activity Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) <=> H+ + a uracil17 in tRNA + NAD(P)H. EC:1.3.1.88|MetaCyc:RXN-12455 go-plus.json http://purl.obolibrary.org/obo/GO_0102263 GO:0102262 biolink:MolecularActivity tRNA-dihydrouridine16 synthase activity Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) <=> H+ + a uracil16 in tRNA + NAD(P)H. MetaCyc:RXN-12454 go-plus.json http://purl.obolibrary.org/obo/GO_0102262 GO:0102265 biolink:MolecularActivity tRNA-dihydrouridine47 synthase activity Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) <=> H+ + a uracil47 in tRNA + NAD(P)H. EC:1.3.1.89|MetaCyc:RXN-12457 go-plus.json http://purl.obolibrary.org/obo/GO_0102265 GO:0102264 biolink:MolecularActivity tRNA-dihydrouridine20 synthase activity Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) <=> H+ + a uracil20 in tRNA + NAD(P)H. EC:1.3.1.91|MetaCyc:RXN-12456 go-plus.json http://purl.obolibrary.org/obo/GO_0102264 GO:0102267 biolink:MolecularActivity tRNA-dihydrouridine20b synthase activity Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) <=> H+ + a uracil20b in tRNA + NAD(P)H. MetaCyc:RXN-12476 go-plus.json http://purl.obolibrary.org/obo/GO_0102267 GO:0102266 biolink:MolecularActivity tRNA-dihydrouridine20a synthase activity Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) <=> H+ + a uracil20a in tRNA + NAD(P)H. EC:1.3.1.90|MetaCyc:RXN-12475 go-plus.json http://purl.obolibrary.org/obo/GO_0102266 CHEBI:83767 biolink:ChemicalSubstance 2''-O-acetyl-ADP-D-ribose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83767 chebi_ph7_3 CHEBI:83762 biolink:ChemicalSubstance EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_83762 CHEBI:83760 biolink:ChemicalSubstance EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_83760 PO:0005352 biolink:OntologyClass xylem A portion of vascular tissue (PO:0009015) that has as part one or more tracheary elements (PO:0000290). go-plus.json 木質部 (Japanese, exact)|portion of xylem tissue (exact)|xilema (Spanish, exact) http://purl.obolibrary.org/obo/PO_0005352 CHEBI:138298 biolink:ChemicalSubstance 2-hydroxyicosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138298 chebi_ph7_3 CHEBI:138297 biolink:ChemicalSubstance 2-hydroxyheptadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138297 chebi_ph7_3 CHEBI:138296 biolink:ChemicalSubstance 2-hydroxyisovaleryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138296 chebi_ph7_3 CHEBI:138295 biolink:ChemicalSubstance (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138295 CHEBI:138299 biolink:ChemicalSubstance 2-hydroxydodecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138299 chebi_ph7_3 CHEBI:138272 biolink:ChemicalSubstance 8,9-epoxy-20-hydroxy-(5Z,11Z,14Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138272 CHEBI:138270 biolink:ChemicalSubstance 12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138270 CHEBI:83778 biolink:ChemicalSubstance 1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83778 CHEBI:83777 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchol-4-en-22-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83777 chebi_ph7_3 CHEBI:83776 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchol-4-en-22-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83776 CHEBI:83775 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycerol-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83775 CHEBI:83774 biolink:ChemicalSubstance 1,2-dioctadecanoyl-sn-glycerol-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83774 CHEBI:138265 biolink:ChemicalSubstance 9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138265 CHEBI:138262 biolink:ChemicalSubstance (9S,10R)-epoxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138262 CHEBI:138269 biolink:ChemicalSubstance 1-O-hexadecyl-2-(8-carboxyoctanoyl)-sn-glycero-3-phosphocholine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138269 chebi_ph7_3 CHEBI:138268 biolink:ChemicalSubstance D-xylulose 1,5-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138268 chebi_ph7_3 CHEBI:138267 biolink:ChemicalSubstance hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138267 chebi_ph7_3 CHEBI:138266 biolink:ChemicalSubstance 2-heptanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138266 chebi_ph7_3 CHEBI:138282 biolink:ChemicalSubstance 5'-end ribonucleotide(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138282 chebi_ph7_3 CHEBI:138281 biolink:ChemicalSubstance 16-oxoresolvin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138281 CHEBI:138280 biolink:ChemicalSubstance adenosine-5'-diphospho-5'-ribonucleotide(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138280 chebi_ph7_3 GO:0102201 biolink:MolecularActivity (+)-2-epi-prezizaene synthase activity Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid. MetaCyc:RXN-12117 go-plus.json http://purl.obolibrary.org/obo/GO_0102201 GO:0043300 biolink:BiologicalProcess regulation of leukocyte degranulation Any process that modulates the frequency, rate, or extent of leukocyte degranulation. go-plus.json regulation of immune cell degranulation|regulation of immune cell granule exocytosis|regulation of leukocyte granule exocytosis|regulation of leucocyte degranulation http://purl.obolibrary.org/obo/GO_0043300 GO:0102200 biolink:MolecularActivity N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate. MetaCyc:RXN-12116|EC:3.1.4.54|RHEA:33159 go-plus.json http://purl.obolibrary.org/obo/GO_0102200 GO:0102203 biolink:MolecularActivity brassicasterol glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+. EC:2.4.1.173|MetaCyc:RXN-12125|RHEA:61840 go-plus.json http://purl.obolibrary.org/obo/GO_0102203 GO:0043302 biolink:BiologicalProcess positive regulation of leukocyte degranulation Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. go-plus.json positive regulation of leucocyte degranulation|up regulation of leukocyte degranulation|activation of leukocyte degranulation|stimulation of leukocyte degranulation|positive regulation of immune cell degranulation|up-regulation of leukocyte degranulation|upregulation of leukocyte degranulation http://purl.obolibrary.org/obo/GO_0043302 GO:0043301 biolink:BiologicalProcess negative regulation of leukocyte degranulation Any process that stops, prevents, or reduces the rate of leukocyte degranulation. go-plus.json down regulation of leukocyte degranulation|downregulation of leukocyte degranulation|negative regulation of leucocyte degranulation|down-regulation of leukocyte degranulation|inhibition of leukocyte degranulation|negative regulation of immune cell degranulation http://purl.obolibrary.org/obo/GO_0043301 GO:0102202 biolink:MolecularActivity soladodine glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+. EC:2.4.1.173|MetaCyc:RXN-12123|RHEA:61844 go-plus.json http://purl.obolibrary.org/obo/GO_0102202 GO:0102205 biolink:MolecularActivity cholesterol alpha-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+. EC:2.4.1.173|MetaCyc:RXN-12127|RHEA:61848 go-plus.json cholesterol UDP-glucosyltransferase activity|cholesterol allpha-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0102205 GO:0102207 biolink:MolecularActivity docosanoate omega-hydroxylase activity Catalysis of the reaction: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. MetaCyc:RXN-12155|RHEA:40079 go-plus.json behenate omega-hydroxylase activity http://purl.obolibrary.org/obo/GO_0102207 CHEBI:83785 biolink:ChemicalSubstance 1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83785 CHEBI:83783 biolink:ChemicalSubstance (25S)-3beta-hydroxy-5-cholesten-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83783 chebi_ph7_3 GO:0043308 biolink:BiologicalProcess eosinophil degranulation The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil. go-plus.json eosinophil granule exocytosis http://purl.obolibrary.org/obo/GO_0043308 GO:0102209 biolink:MolecularActivity trans-permethrin hydrolase activity Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate. MetaCyc:RXN-12167|EC:3.1.1.88|RHEA:30283 go-plus.json http://purl.obolibrary.org/obo/GO_0102209 GO:0043307 biolink:BiologicalProcess eosinophil activation The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0043307 GO:0102208 biolink:MolecularActivity 2-polyprenyl-6-hydroxyphenol methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol. MetaCyc:RXN-12160|RHEA:31411 go-plus.json http://purl.obolibrary.org/obo/GO_0102208 GO:0043309 biolink:BiologicalProcess regulation of eosinophil degranulation Any process that modulates the frequency, rate, or extent of eosinophil degranulation. go-plus.json regulation of eosinophil granule exocytosis http://purl.obolibrary.org/obo/GO_0043309 GO:0043304 biolink:BiologicalProcess regulation of mast cell degranulation Any process that modulates the frequency, rate, or extent of mast cell degranulation. go-plus.json regulation of mast cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043304 GO:0043303 biolink:BiologicalProcess mast cell degranulation The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. go-plus.json mast cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043303 GO:0043306 biolink:BiologicalProcess positive regulation of mast cell degranulation Any process that activates or increases the frequency, rate or extent of mast cell degranulation. go-plus.json up regulation of mast cell degranulation|activation of mast cell degranulation|stimulation of mast cell degranulation|up-regulation of mast cell degranulation|positive regulation of mast cell granule exocytosis|upregulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043306 GO:0043305 biolink:BiologicalProcess negative regulation of mast cell degranulation Any process that stops, prevents, or reduces the rate of mast cell degranulation. go-plus.json downregulation of mast cell degranulation|down-regulation of mast cell degranulation|inhibition of mast cell degranulation|negative regulation of mast cell granule exocytosis|down regulation of mast cell degranulation http://purl.obolibrary.org/obo/GO_0043305 CHEBI:138276 biolink:ChemicalSubstance 5'-end purine ribonucleoside 5'-diphosphate(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138276 chebi_ph7_3 CHEBI:138275 biolink:ChemicalSubstance oxidized Renilla luciferin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138275 chebi_ph7_3 CHEBI:138274 biolink:ChemicalSubstance 14,15-epoxy-20-hydroxy-(5Z,8Z,11Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138274 CHEBI:138273 biolink:ChemicalSubstance 11,12-epoxy-20-hydroxy-(5Z,8Z,14Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138273 CHEBI:138279 biolink:ChemicalSubstance 7-oxoresolvin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138279 CHEBI:138278 biolink:ChemicalSubstance 5'-end GTP-ribonucleotide(5-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138278 chebi_ph7_3 GO:0018391 biolink:BiologicalProcess C-terminal peptidyl-glutamic acid tyrosinylation The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018391 GO:0018390 biolink:BiologicalProcess peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester. RESID:AA0072 go-plus.json peptidyl-L-glutamic acid 5-methyl ester anabolism from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester synthesis from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester formation from peptidyl-glutamic acid or peptidyl-glutamine http://purl.obolibrary.org/obo/GO_0018390 GO:0018393 biolink:BiologicalProcess internal peptidyl-lysine acetylation The addition of an acetyl group to a non-terminal lysine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018393 GO:0018392 biolink:MolecularActivity glycoprotein 3-alpha-L-fucosyltransferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+). MetaCyc:2.4.1.214-RXN|RHEA:24444|KEGG_REACTION:R06015|EC:2.4.1.214 go-plus.json GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity|GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity http://purl.obolibrary.org/obo/GO_0018392 GO:0102210 biolink:MolecularActivity rhamnogalacturonan endolyase activity Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide]. MetaCyc:RXN-12173|EC:4.2.2.23 go-plus.json http://purl.obolibrary.org/obo/GO_0102210 GO:0043311 biolink:BiologicalProcess positive regulation of eosinophil degranulation Any process that activates or increases the frequency, rate or extent of eosinophil degranulation. go-plus.json stimulation of eosinophil degranulation|up-regulation of eosinophil degranulation|activation of eosinophil degranulation|positive regulation of eosinophil granule exocytosis|up regulation of eosinophil degranulation|upregulation of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043311 GO:0102212 biolink:MolecularActivity unsaturated chondroitin disaccharide hydrolase activity Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate. MetaCyc:RXN-12177|EC:3.2.1.180|RHEA:31647 go-plus.json http://purl.obolibrary.org/obo/GO_0102212 GO:0102211 biolink:MolecularActivity unsaturated rhamnogalacturonyl hydrolase activity Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose. EC:3.2.1.172|RHEA:30927|MetaCyc:RXN-12174 go-plus.json http://purl.obolibrary.org/obo/GO_0102211 GO:0043310 biolink:BiologicalProcess negative regulation of eosinophil degranulation Any process that stops, prevents, or reduces the rate of eosinophil degranulation. go-plus.json negative regulation of eosinophil granule exocytosis|down-regulation of eosinophil degranulation|downregulation of eosinophil degranulation|down regulation of eosinophil degranulation|inhibition of eosinophil degranulation http://purl.obolibrary.org/obo/GO_0043310 GO:0102214 biolink:MolecularActivity omega-hydroxy fatty acyl-CoA synthetase activity Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA. MetaCyc:RXN-12185 go-plus.json http://purl.obolibrary.org/obo/GO_0102214 GO:0043313 biolink:BiologicalProcess regulation of neutrophil degranulation Any process that modulates the frequency, rate, or extent of neutrophil degranulation. go-plus.json regulation of neutrophil granule exocytosis http://purl.obolibrary.org/obo/GO_0043313 GO:0043312 biolink:BiologicalProcess neutrophil degranulation The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. go-plus.json heterophil degranulation|neutrophil granule exocytosis http://purl.obolibrary.org/obo/GO_0043312 GO:0102213 biolink:MolecularActivity in-chain hydroxy fatty acyl-CoA synthetase activity Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA. MetaCyc:RXN-12184 go-plus.json http://purl.obolibrary.org/obo/GO_0102213 GO:0102216 biolink:MolecularActivity maltodextrin water dikinase Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin. EC:2.7.9.4|MetaCyc:RXN-12201 go-plus.json http://purl.obolibrary.org/obo/GO_0102216 CHEBI:83798 biolink:ChemicalSubstance N-hexanoylsphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83798 GO:0102215 biolink:MolecularActivity thiocyanate methyltransferase activity Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine <=> methyl thiocyanate + S-adenosyl-L-homocysteine. RHEA:28014|MetaCyc:RXN-12189 go-plus.json http://purl.obolibrary.org/obo/GO_0102215 CHEBI:83797 biolink:ChemicalSubstance 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83797 chebi_ph7_3 GO:0102218 biolink:MolecularActivity starch, H2O dikinase activity Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin. EC:2.7.9.4|MetaCyc:RXN-12203 go-plus.json http://purl.obolibrary.org/obo/GO_0102218 CHEBI:83796 biolink:ChemicalSubstance 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83796 CHEBI:83795 biolink:ChemicalSubstance 3-oxodotriacontanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83795 chebi_ph7_3 GO:0102217 biolink:MolecularActivity 6-phosphoglucan, water dikinase activity Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin. RHEA:10256|MetaCyc:RXN-12202|EC:2.7.9.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102217 GO:0043319 biolink:BiologicalProcess positive regulation of cytotoxic T cell degranulation Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation. go-plus.json positive regulation of cytotoxic T-cell granule exocytosis|up regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T lymphocyte degranulation|positive regulation of cytotoxic T lymphocyte granule exocytosis|upregulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T cell granule exocytosis|stimulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-cell degranulation|activation of cytotoxic T cell degranulation|up-regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-lymphocyte degranulation|positive regulation of cytotoxic T-lymphocyte granule exocytosis http://purl.obolibrary.org/obo/GO_0043319 CHEBI:83794 biolink:ChemicalSubstance 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83794 chebi_ph7_3 GO:0102219 biolink:MolecularActivity phosphogluco-amylopectin water dikinase activity Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin. EC:2.7.9.5|MetaCyc:RXN-12204 go-plus.json http://purl.obolibrary.org/obo/GO_0102219 GO:0043318 biolink:BiologicalProcess negative regulation of cytotoxic T cell degranulation Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. go-plus.json down-regulation of cytotoxic T cell degranulation|negative regulation of cytotoxic T-lymphocyte granule exocytosis|negative regulation of cytotoxic T-cell granule exocytosis|negative regulation of cytotoxic T lymphocyte degranulation|downregulation of cytotoxic T cell degranulation|down regulation of cytotoxic T cell degranulation|inhibition of cytotoxic T cell degranulation|negative regulation of cytotoxic T lymphocyte granule exocytosis|negative regulation of cytotoxic T-cell degranulation|negative regulation of cytotoxic T-lymphocyte degranulation|negative regulation of cytotoxic T cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043318 CHEBI:83793 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83793 chebi_ph7_3 CHEBI:83792 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83792 chebi_ph7_3 GO:0043315 biolink:BiologicalProcess positive regulation of neutrophil degranulation Any process that activates or increases the frequency, rate or extent of neutrophil degranulation. go-plus.json up regulation of neutrophil degranulation|upregulation of neutrophil degranulation|stimulation of neutrophil degranulation|up-regulation of neutrophil degranulation|activation of neutrophil degranulation|positive regulation of neutrophil granule exocytosis http://purl.obolibrary.org/obo/GO_0043315 GO:0043314 biolink:BiologicalProcess negative regulation of neutrophil degranulation Any process that stops, prevents, or reduces the rate of neutrophil degranulation. go-plus.json downregulation of neutrophil degranulation|down regulation of neutrophil degranulation|inhibition of neutrophil degranulation|down-regulation of neutrophil degranulation|negative regulation of neutrophil granule exocytosis http://purl.obolibrary.org/obo/GO_0043314 GO:0043317 biolink:BiologicalProcess regulation of cytotoxic T cell degranulation Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation. go-plus.json regulation of cytotoxic T-cell degranulation|regulation of cytotoxic T-lymphocyte degranulation|regulation of cytotoxic T lymphocyte granule exocytosis|regulation of cytotoxic T cell granule exocytosis|regulation of cytotoxic T lymphocyte degranulation|regulation of cytotoxic T-lymphocyte granule exocytosis|regulation of cytotoxic T-cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043317 GO:0043316 biolink:BiologicalProcess cytotoxic T cell degranulation The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. go-plus.json cytotoxic T lymphocyte degranulation|cytotoxic T-lymphocyte granule exocytosis|cytotoxic T-cell granule exocytosis|cytotoxic T-cell degranulation|cytotoxic T-lymphocyte degranulation|cytotoxic T lymphocyte granule exocytosis|cytotoxic T cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043316 GO:0018388 biolink:BiologicalProcess N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine. RESID:AA0275 go-plus.json http://purl.obolibrary.org/obo/GO_0018388 GO:0018387 biolink:BiologicalProcess N-terminal peptidyl-amino acid deamination to pyruvic acid The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue. RESID:AA0127 go-plus.json http://purl.obolibrary.org/obo/GO_0018387 GO:0018389 biolink:BiologicalProcess N-terminal peptidyl-valine deamination The deamination of the N-terminal valine residue of a protein to form isobutyrate. go-plus.json http://purl.obolibrary.org/obo/GO_0018389 GO:0018384 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018384 CHEBI:138247 biolink:ChemicalSubstance cycloaraneosene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138247 chebi_ph7_3 GO:0018383 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018383 GO:0018386 biolink:BiologicalProcess N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine. RESID:AA0274 go-plus.json http://purl.obolibrary.org/obo/GO_0018386 GO:0018385 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018385 CHEBI:138261 biolink:ChemicalSubstance very long-chain fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138261 chebi_ph7_3 CHEBI:138260 biolink:ChemicalSubstance (9R,10S)-9,10-epoxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138260 GO:0102220 biolink:MolecularActivity hydrogenase activity (NAD+, ferredoxin) Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin. RHEA:30279|EC:1.12.1.4|MetaCyc:RXN-12215 go-plus.json http://purl.obolibrary.org/obo/GO_0102220 GO:0102223 biolink:MolecularActivity 4,4'-diapophytoene desaturase activity Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD <=> 4,4'-diapolycopene + 4 FADH2. MetaCyc:RXN-12224|EC:1.3.8.2|RHEA:31391 go-plus.json http://purl.obolibrary.org/obo/GO_0102223 GO:0043322 biolink:BiologicalProcess negative regulation of natural killer cell degranulation Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. go-plus.json negative regulation of natural killer cell granule exocytosis|down regulation of natural killer cell degranulation|negative regulation of NK cell granule exocytosis|downregulation of natural killer cell degranulation|negative regulation of NK cell degranulation|down-regulation of natural killer cell degranulation|inhibition of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043322 GO:0043321 biolink:BiologicalProcess regulation of natural killer cell degranulation Any process that modulates the frequency, rate, or extent of natural killer cell degranulation. go-plus.json regulation of NK cell degranulation|regulation of natural killer cell granule exocytosis|regulation of NK cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043321 GO:0102222 biolink:MolecularActivity obsolete 6-phosophogluco-3-phosphogluco-starch phosphatase activity OBSOLETE. Catalysis of the reaction: m+q H2O + a 6-phosphogluco-3-phosphogluco-amylopectin <=> m+q hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin. MetaCyc:RXN-12218 go-plus.json http://purl.obolibrary.org/obo/GO_0102222 GO:0102225 biolink:MolecularActivity 4,4'-diaponeurosporene desaturase activity Catalysis of the reaction: 4,4'-diaponeurosporene + FAD + H+ <=> 4,4'-diapolycopene + FADH2. MetaCyc:RXN-12258|RHEA:31407 go-plus.json http://purl.obolibrary.org/obo/GO_0102225 GO:0043324 biolink:BiologicalProcess pigment metabolic process involved in developmental pigmentation The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism. go-plus.json pigment metabolic process during developmental pigmentation|pigment metabolism during developmental pigmentation http://purl.obolibrary.org/obo/GO_0043324 GO:0102224 biolink:MolecularActivity GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+. MetaCyc:RXN-12236|RHEA:46316 go-plus.json http://purl.obolibrary.org/obo/GO_0102224 GO:0043323 biolink:BiologicalProcess positive regulation of natural killer cell degranulation Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation. go-plus.json upregulation of natural killer cell degranulation|positive regulation of natural killer cell granule exocytosis|positive regulation of NK cell degranulation|positive regulation of NK cell granule exocytosis|up regulation of natural killer cell degranulation|activation of natural killer cell degranulation|stimulation of natural killer cell degranulation|up-regulation of natural killer cell degranulation http://purl.obolibrary.org/obo/GO_0043323 GO:0043320 biolink:BiologicalProcess natural killer cell degranulation The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. go-plus.json NK cell granule exocytosis|NK cell degranulation|natural killer cell granule exocytosis http://purl.obolibrary.org/obo/GO_0043320 GO:0102229 biolink:MolecularActivity amylopectin maltohydrolase activity Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin <=> amylopectin + maltose. MetaCyc:RXN-12278|EC:3.2.1.2 go-plus.json http://purl.obolibrary.org/obo/GO_0102229 GO:0043329 biolink:BiologicalProcess obsolete protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway OBSOLETE. The process of directing proteins towards a membrane using signals contained within the protein, occurring that contributes to ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway. go-plus.json protein-membrane targeting during ubiquitin-dependent protein breakdown via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein degradation via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein breakdown via the MVB pathway http://purl.obolibrary.org/obo/GO_0043329 GO:0043326 biolink:BiologicalProcess chemotaxis to folate The directed movement of a motile cell or organism in response to the presence of folate. go-plus.json http://purl.obolibrary.org/obo/GO_0043326 GO:0043325 biolink:MolecularActivity phosphatidylinositol-3,4-bisphosphate binding Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions. go-plus.json http://purl.obolibrary.org/obo/GO_0043325 GO:0043328 biolink:BiologicalProcess protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway. go-plus.json protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein breakdown via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein breakdown via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein degradation via the MVB pathway http://purl.obolibrary.org/obo/GO_0043328 GO:0043327 biolink:BiologicalProcess chemotaxis to cAMP The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP. go-plus.json chemotaxis to adenosine 3',5'-cyclophosphate|chemotaxis to cyclic AMP|chemotaxis to 3',5' cAMP|chemotaxis to 3',5'-cAMP http://purl.obolibrary.org/obo/GO_0043327 GO:0018399 biolink:BiologicalProcess peptidyl-phenylalanine bromination to L-4'-bromophenylalanine The bromination of peptidyl-phenylalanine to form L-4'-bromophenylalanine. RESID:AA0176 go-plus.json http://purl.obolibrary.org/obo/GO_0018399 GO:0018398 biolink:BiologicalProcess peptidyl-phenylalanine bromination to L-3'-bromophenylalanine The bromination of peptidyl-phenylalanine to form L-3'-bromophenylalanine. RESID:AA0175 go-plus.json http://purl.obolibrary.org/obo/GO_0018398 GO:0018395 biolink:BiologicalProcess peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine. RESID:AA0028 go-plus.json http://purl.obolibrary.org/obo/GO_0018395 CHEBI:138258 biolink:ChemicalSubstance (9R,10S)-9,10-epoxy-18-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138258 GO:0018394 biolink:BiologicalProcess peptidyl-lysine acetylation The acetylation of peptidyl-lysine. go-plus.json http://purl.obolibrary.org/obo/GO_0018394 GO:0018397 biolink:BiologicalProcess peptidyl-phenylalanine bromination to L-2'-bromophenylalanine The bromination of peptidyl-phenylalanine to form L-2'-bromophenylalanine. RESID:AA0174 go-plus.json http://purl.obolibrary.org/obo/GO_0018397 CHEBI:138256 biolink:ChemicalSubstance N-(4-oxoglutaryl)-L-cysteinylglycine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138256 chebi_ph7_3 GO:0018396 biolink:BiologicalProcess peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine. RESID:AA0235 go-plus.json http://purl.obolibrary.org/obo/GO_0018396 CHEBI:138255 biolink:ChemicalSubstance (9S,10R)-9,10-epoxy-18-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138255 PO:0005417 biolink:OntologyClass phloem A portion of vascular tissue (PO:0009015) that has as parts sieve elements (PO:0025406). go-plus.json portion of phloem tissue (exact)|floema (Spanish, exact)|師部、師管 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0005417 UBERON:0005594 biolink:AnatomicalEntity head somite Somite located in the head region, caudal to the otic vesicle go-plus.json occipital somite|cranial somite http://purl.obolibrary.org/obo/UBERON_0005594 UBERON:0005590 biolink:AnatomicalEntity rhombomere 8 roof plate A rhombomere roof plate that is part of a rhombomere 8. go-plus.json roof plate rhombomere 8 http://purl.obolibrary.org/obo/UBERON_0005590 PO:0005421 biolink:OntologyClass parenchyma A portion of ground tissue (PO:0025059) composed of polyhedral cells typically with thin, non-lignified cellulosic cell walls and nucleate, living protoplasts. go-plus.json portion of parenchymatous tissue (exact)|parénquima (Spanish, exact)|portion of parenchyma tissue (exact)|柔組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0005421 UBERON:0005598 biolink:AnatomicalEntity trunk somite A somite that is part of a trunk. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005598 UBERON:0005597 biolink:AnatomicalEntity lung primordium A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum. go-plus.json lung diverticulum|lateral diverticula|lung endoderm http://purl.obolibrary.org/obo/UBERON_0005597 UBERON:0005584 biolink:AnatomicalEntity rhombomere 6 roof plate A rhombomere roof plate that is part of a rhombomere 6. go-plus.json roof plate rhombomere 6 http://purl.obolibrary.org/obo/UBERON_0005584 UBERON:0005583 biolink:AnatomicalEntity rhombomere 6 lateral wall A rhombomere lateral wall that is part of a rhombomere 6. go-plus.json lateral wall rhombomere 6 http://purl.obolibrary.org/obo/UBERON_0005583 UBERON:0005581 biolink:AnatomicalEntity rhombomere 5 roof plate A rhombomere roof plate that is part of a rhombomere 5. go-plus.json roof plate rhombomere 5 http://purl.obolibrary.org/obo/UBERON_0005581 UBERON:0005580 biolink:AnatomicalEntity rhombomere 5 lateral wall A rhombomere lateral wall that is part of a rhombomere 5. go-plus.json lateral wall rhombomere 5 http://purl.obolibrary.org/obo/UBERON_0005580 UBERON:0005589 biolink:AnatomicalEntity rhombomere 8 lateral wall A rhombomere lateral wall that is part of a rhombomere 8. go-plus.json lateral wall rhombomere 8 http://purl.obolibrary.org/obo/UBERON_0005589 UBERON:0005587 biolink:AnatomicalEntity rhombomere 7 roof plate A rhombomere roof plate that is part of a rhombomere 7. go-plus.json roof plate rhombomere 7 http://purl.obolibrary.org/obo/UBERON_0005587 UBERON:0005586 biolink:AnatomicalEntity rhombomere 7 lateral wall A rhombomere lateral wall that is part of a rhombomere 7. go-plus.json lateral wall rhombomere 7 http://purl.obolibrary.org/obo/UBERON_0005586 UBERON:0005574 biolink:AnatomicalEntity rhombomere 3 lateral wall A rhombomere lateral wall that is part of a rhombomere 3. go-plus.json lateral wall rhombomere 3 http://purl.obolibrary.org/obo/UBERON_0005574 UBERON:0005572 biolink:AnatomicalEntity rhombomere 2 roof plate A rhombomere roof plate that is part of a rhombomere 2. go-plus.json roof plate rhombomere 2 http://purl.obolibrary.org/obo/UBERON_0005572 UBERON:0005571 biolink:AnatomicalEntity rhombomere 2 lateral wall A rhombomere lateral wall that is part of a rhombomere 2. go-plus.json lateral wall rhombomere 2 http://purl.obolibrary.org/obo/UBERON_0005571 UBERON:0005578 biolink:AnatomicalEntity rhombomere 4 roof plate A rhombomere roof plate that is part of a rhombomere 4. go-plus.json roof plate rhombomere 4 http://purl.obolibrary.org/obo/UBERON_0005578 UBERON:0005577 biolink:AnatomicalEntity rhombomere 4 lateral wall A rhombomere lateral wall that is part of a rhombomere 4. go-plus.json lateral wall rhombomere 4 http://purl.obolibrary.org/obo/UBERON_0005577 UBERON:0005575 biolink:AnatomicalEntity rhombomere 3 roof plate A rhombomere roof plate that is part of a rhombomere 3. go-plus.json roof plate rhombomere 3 http://purl.obolibrary.org/obo/UBERON_0005575 CHEBI:34718 biolink:ChemicalSubstance 1-chloro-2,4-dinitrobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_34718 chebi_ph7_3 UBERON:0005563 biolink:AnatomicalEntity trigeminal neural crest Cranial neural crest which gives rise to the trigeminal ganglion. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005563 UBERON:0005562 biolink:AnatomicalEntity thymus primordium A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production[ZFA]. [PMID]. go-plus.json thymic primordium|thymic rudiment http://purl.obolibrary.org/obo/UBERON_0005562 UBERON:0005569 biolink:AnatomicalEntity rhombomere 2 the second transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r2 http://purl.obolibrary.org/obo/UBERON_0005569 UBERON:0005568 biolink:AnatomicalEntity rhombomere 1 roof plate A rhombomere roof plate that is part of a rhombomere 1. go-plus.json roof plate rhombomere 1 http://purl.obolibrary.org/obo/UBERON_0005568 UBERON:0005567 biolink:AnatomicalEntity rhombomere 1 lateral wall A rhombomere lateral wall that is part of a rhombomere 1. go-plus.json lateral wall rhombomere 1 http://purl.obolibrary.org/obo/UBERON_0005567 UBERON:0005565 biolink:AnatomicalEntity facio-acoustic neural crest Cranial neural crest that gives rise to the facio-acoustic ganglion. go-plus.json facio acoustic neural crest http://purl.obolibrary.org/obo/UBERON_0005565 UBERON:0005564 biolink:AnatomicalEntity gonad primordium Portion of tissue that gives rise to the immature gonad. go-plus.json gonadal primordium|immature gonad|primitive gonad|future gonad|undifferentiated gonad http://purl.obolibrary.org/obo/UBERON_0005564 GO:0102272 biolink:MolecularActivity homophytochelatin synthase activity (polymer-forming) Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine. MetaCyc:RXN-12528 go-plus.json http://purl.obolibrary.org/obo/GO_0102272 GO:0102274 biolink:MolecularActivity glutathione S-conjugate carboxypeptidase activity Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate. MetaCyc:RXN-12532 go-plus.json http://purl.obolibrary.org/obo/GO_0102274 GO:0102273 biolink:MolecularActivity homophytochelatin synthase (dimmer forming) activity Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine. MetaCyc:RXN-12529 go-plus.json http://purl.obolibrary.org/obo/GO_0102273 GO:0102276 biolink:MolecularActivity 2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ <=> ethene + 3 carbon dioxide + H2O. EC:1.13.12.19|MetaCyc:RXN-12538|RHEA:31523 go-plus.json http://purl.obolibrary.org/obo/GO_0102276 GO:0102275 biolink:MolecularActivity cysteine-S-conjugate N-malonyl transferase activity Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate <=> coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate. MetaCyc:RXN-12534 go-plus.json http://purl.obolibrary.org/obo/GO_0102275 GO:0102278 biolink:MolecularActivity N,N'-diacetylchitobiose synthase activity Catalysis of the reaction: n H2O + chitin <=> N,N'-diacetylchitobiose. MetaCyc:RXN-12554 go-plus.json http://purl.obolibrary.org/obo/GO_0102278 GO:0102277 biolink:MolecularActivity 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine. MetaCyc:RXN-12544 go-plus.json http://purl.obolibrary.org/obo/GO_0102277 GO:0102279 biolink:MolecularActivity lecithin:11-cis retinol acyltransferase activity Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine. EC:2.3.1.135|MetaCyc:RXN-12563 go-plus.json http://purl.obolibrary.org/obo/GO_0102279 GO:0102281 biolink:MolecularActivity formylaminopyrimidine deformylase activity Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate. MetaCyc:RXN-12612 go-plus.json http://purl.obolibrary.org/obo/GO_0102281 GO:0102280 biolink:MolecularActivity choline monooxygenase activity (NADP-dependent) Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+. MetaCyc:RXN-12582 go-plus.json http://purl.obolibrary.org/obo/GO_0102280 GO:0102283 biolink:MolecularActivity 3-ketodihydrosphinganine (C20) reductase activity Catalysis of the reaction: C20 sphinganine(1+) + NADP <=> C20 3-dehydrosphinganine(1+) + NADPH + H+. MetaCyc:RXN-12642 go-plus.json http://purl.obolibrary.org/obo/GO_0102283 GO:0102282 biolink:MolecularActivity 3-ketodihydrosphinganine (C18) reductase activity Catalysis of the reaction: NAD(1-) + a sphinganine <=> 3-dehydrosphinganinium(1+) + NADH + H+. MetaCyc:RXN-12641 go-plus.json http://purl.obolibrary.org/obo/GO_0102282 GO:0102285 biolink:MolecularActivity 1-deoxy-11-oxopentalenate oxygenase activity Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP. EC:1.14.13.170|RHEA:34635|MetaCyc:RXN-12654 go-plus.json http://purl.obolibrary.org/obo/GO_0102285 GO:0102284 biolink:MolecularActivity L-threo-sphinganine reductase activity Catalysis of the reaction: L-threo-sphinganine + NADP <=> H+ + NADPH + 3-dehydrosphinganinium(1+). MetaCyc:RXN-12645 go-plus.json http://purl.obolibrary.org/obo/GO_0102284 GO:0102287 biolink:MolecularActivity 4-coumaroylhexanoylmethane synthase activity Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide. MetaCyc:RXN-12668 go-plus.json http://purl.obolibrary.org/obo/GO_0102287 GO:0102286 biolink:MolecularActivity ornithine N-delta-acetyltransferase activity Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine. MetaCyc:RXN-12667 go-plus.json http://purl.obolibrary.org/obo/GO_0102286 GO:0102289 biolink:MolecularActivity beta-amyrin 11-oxidase activity Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP. RHEA:31711|MetaCyc:RXN-12680|EC:1.14.14.152 go-plus.json http://purl.obolibrary.org/obo/GO_0102289 GO:0102290 biolink:MolecularActivity beta-amyrin monooxygenase activity Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP. MetaCyc:RXN-12681|RHEA:31715|EC:1.14.14.152 go-plus.json http://purl.obolibrary.org/obo/GO_0102290 GO:0102292 biolink:MolecularActivity 30-hydroxy-beta-amyrin 11-hydroxylase activity Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP. MetaCyc:RXN-12683 go-plus.json http://purl.obolibrary.org/obo/GO_0102292 GO:0102291 biolink:MolecularActivity 11alpha-hydroxy-beta-amyrin dehydrogenase activity Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP. RHEA:31719|MetaCyc:RXN-12682|EC:1.14.14.152 go-plus.json http://purl.obolibrary.org/obo/GO_0102291 GO:0102294 biolink:MolecularActivity cholesterol dehydrogenase activity Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+. EC:1.1.1.145|MetaCyc:RXN-12693|RHEA:35459 go-plus.json http://purl.obolibrary.org/obo/GO_0102294 GO:0102293 biolink:MolecularActivity pheophytinase b activity Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol. MetaCyc:RXN-12686|EC:3.1.1.14 go-plus.json http://purl.obolibrary.org/obo/GO_0102293 CHEBI:83718 biolink:ChemicalSubstance 1,2-distearoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83718 chebi_ph7_3 GO:0102296 biolink:MolecularActivity 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+. EC:3.7.1.17|RHEA:32035|MetaCyc:RXN-12718 go-plus.json http://purl.obolibrary.org/obo/GO_0102296 CHEBI:83717 biolink:ChemicalSubstance 1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83717 chebi_ph7_3 GO:0102295 biolink:MolecularActivity 4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A. MetaCyc:RXN-12699 go-plus.json http://purl.obolibrary.org/obo/GO_0102295 CHEBI:83716 biolink:ChemicalSubstance 2-aminophenylglyoxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83716 GO:0102298 biolink:MolecularActivity selenocystathione synthase activity Catalysis of the reaction: L-selenocysteine + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine. MetaCyc:RXN-12728 go-plus.json http://purl.obolibrary.org/obo/GO_0102298 GO:0102297 biolink:MolecularActivity selenate adenylyltransferase activity Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid. MetaCyc:RXN-12720 go-plus.json http://purl.obolibrary.org/obo/GO_0102297 CHEBI:83714 biolink:ChemicalSubstance 1,2,2'-trilinoleoyl-1'-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83714 chebi_ph7_3 GO:0102299 biolink:MolecularActivity linolenate 9R-lipoxygenase activity Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate. EC:1.13.11.61|RHEA:31687|MetaCyc:RXN-12759 go-plus.json http://purl.obolibrary.org/obo/GO_0102299 PO:0005426 biolink:OntologyClass chlorenchyma Chloroplast-containing parenchyma tissue. go-plus.json portion of chlorenchyma tissue (exact)|clorénquima (Spanish, exact)|同化組織、葉緑組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0005426 PO:0005423 biolink:OntologyClass collenchyma A portion of ground tissue (PO:0025059) which comprises living tissue composed of more or less elongated cells with thick, non-lignified primary cell walls. go-plus.json colénquima (Spanish, exact)|厚角組織 (Japanese, exact)|portion of collenchyma tissue (exact)|supporting tissue (related) http://purl.obolibrary.org/obo/PO_0005423 CHEBI:83728 biolink:ChemicalSubstance very long-chain 2,3-trans-enoyl CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83728 chebi_ph7_3 CHEBI:83727 biolink:ChemicalSubstance long-chain 2,3-trans-enoyl CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83727 chebi_ph7_3 CHEBI:83726 biolink:ChemicalSubstance medium-chain 2,3-trans-enoyl CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83726 chebi_ph7_3 CHEBI:83725 biolink:ChemicalSubstance primary alkymercury(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83725 chebi_ph7_3 CHEBI:83724 biolink:ChemicalSubstance very long-chain 3-substituted propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83724 chebi_ph7_3 CHEBI:83723 biolink:ChemicalSubstance medium-chain 3-substituted propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83723 chebi_ph7_3 CHEBI:10723 biolink:ChemicalSubstance trans-dec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_10723 CHEBI:83721 biolink:ChemicalSubstance long-chain 3-substituted propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83721 chebi_ph7_3 GO:0033927 biolink:MolecularActivity glucan 1,4-alpha-maltohexaosidase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends. EC:3.2.1.98|MetaCyc:3.2.1.98-RXN go-plus.json G6-amylase activity|maltohexaose-producing amylase activity|1,4-alpha-D-glucan maltohexaohydrolase activity|exo-maltohexaohydrolase activity http://purl.obolibrary.org/obo/GO_0033927 GO:0043292 biolink:CellularComponent contractile fiber Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. go-plus.json contractile fibre http://purl.obolibrary.org/obo/GO_0043292 GO:0043291 biolink:CellularComponent RAVE complex A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme. go-plus.json regulator of the (H+)-ATPase of the vacuolar and endosomal membranes http://purl.obolibrary.org/obo/GO_0043291 GO:0033926 biolink:MolecularActivity glycopeptide alpha-N-acetylgalactosaminidase activity Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins. EC:3.2.1.97|MetaCyc:3.2.1.97-RXN go-plus.json endo-alpha-acetylgalactosaminidase activity|D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity|endo-alpha-N-acetylgalactosaminidase activity http://purl.obolibrary.org/obo/GO_0033926 GO:0033925 biolink:MolecularActivity mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. EC:3.2.1.96|Reactome:R-HSA-8853379|MetaCyc:3.2.1.96-RXN go-plus.json endoglycosidase H activity|endo-N-acetyl-beta-D-glucosaminidase activity|di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity|glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity|endoglycosidase S activity|endo-N-acetyl-beta-glucosaminidase activity|endo-beta-acetylglucosaminidase activity|endo-beta-N-acetylglucosaminidase activity|endo-beta-N-acetylglucosaminidase D activity|endo-beta-N-acetylglucosaminidase F activity|endo-beta-N-acetylglucosaminidase H activity|N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity|endo-beta-(1->4)-N-acetylglucosaminidase activity|mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity|endo-beta-N-acetylglucosaminidase L activity|mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity|glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity http://purl.obolibrary.org/obo/GO_0033925 GO:0043294 biolink:CellularComponent mitochondrial glutamate synthase complex (NADH) A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity. go-plus.json http://purl.obolibrary.org/obo/GO_0043294 GO:0008969 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008969 GO:0043293 biolink:CellularComponent apoptosome A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms. Wikipedia:Apoptosome go-plus.json http://purl.obolibrary.org/obo/GO_0043293 GO:0008968 biolink:MolecularActivity D-sedoheptulose 7-phosphate isomerase activity Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate. RHEA:27489|MetaCyc:RXN0-4301 go-plus.json phosphoheptose isomerase activity http://purl.obolibrary.org/obo/GO_0008968 GO:0033924 biolink:MolecularActivity dextran 1,6-alpha-isomaltotriosidase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains. EC:3.2.1.95|MetaCyc:3.2.1.95-RXN go-plus.json 1,6-alpha-D-glucan isomaltotriohydrolase activity|exo-isomaltotriohydrolase activity http://purl.obolibrary.org/obo/GO_0033924 GO:0033923 biolink:MolecularActivity glucan 1,6-alpha-isomaltosidase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains. EC:3.2.1.94|MetaCyc:3.2.1.94-RXN go-plus.json isomaltodextranase activity|isomalto-dextranase activity|1,6-alpha-D-glucan isomaltohydrolase activity|G2-dextranase activity|exo-isomaltohydrolase activity http://purl.obolibrary.org/obo/GO_0033923 GO:0008967 biolink:MolecularActivity phosphoglycolate phosphatase activity Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate. MetaCyc:GPH-RXN|EC:3.1.3.18|KEGG_REACTION:R01334|RHEA:14369 go-plus.json phosphoglycolate hydrolase activity|2-phosphoglycolate phosphatase activity|P-glycolate phosphatase activity|2-phosphoglycolate phosphohydrolase activity|phosphoglycollate phosphatase activity http://purl.obolibrary.org/obo/GO_0008967 GO:0033922 biolink:MolecularActivity peptidoglycan beta-N-acetylmuramidase activity Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues. EC:3.2.1.92|MetaCyc:3.2.1.92-RXN go-plus.json peptidoglycan beta-N-acetylmuramoylexohydrolase activity|exo-beta-N-acetylmuramidase activity|exo-beta-acetylmuramidase activity|beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity http://purl.obolibrary.org/obo/GO_0033922 GO:0008966 biolink:MolecularActivity phosphoglucosamine mutase activity Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. KEGG_REACTION:R02060|MetaCyc:5.4.2.10-RXN|RHEA:23424|EC:5.4.2.10 go-plus.json alpha-D-glucosamine 1,6-phosphomutase activity|D-glucosamine 1,6-phosphomutase activity http://purl.obolibrary.org/obo/GO_0008966 GO:0008965 biolink:MolecularActivity phosphoenolpyruvate-protein phosphotransferase activity Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine. RHEA:23880|MetaCyc:2.7.3.9-RXN|EC:2.7.3.9 go-plus.json enzyme I of the phosphotransferase system|phosphoenolpyruvate--protein phosphatase activity|phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity|phosphopyruvate--protein phosphotransferase activity|sugar--PEP phosphotransferase enzyme I activity|phosphoenolpyruvate sugar phosphotransferase enzyme I activity|phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity|phosphopyruvate--protein factor phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008965 GO:0043290 biolink:BiologicalProcess apocarotenoid catabolic process The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid. go-plus.json apo carotenoid catabolic process|apocarotenoid degradation|apocarotenoid breakdown|apocarotenoid catabolism http://purl.obolibrary.org/obo/GO_0043290 GO:0033921 biolink:MolecularActivity capsular-polysaccharide endo-1,3-alpha-galactosidase activity Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide. EC:3.2.1.87|MetaCyc:3.2.1.87-RXN go-plus.json polysaccharide depolymerase activity|capsular polysaccharide galactohydrolase activity|aerobacter-capsular-polysaccharide galactohydrolase activity http://purl.obolibrary.org/obo/GO_0033921 UBERON:0005507 biolink:AnatomicalEntity rhombomere 3 the third transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r3 http://purl.obolibrary.org/obo/UBERON_0005507 GO:0008964 biolink:MolecularActivity phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-. RHEA:28370|MetaCyc:PEPCARBOX-RXN|EC:4.1.1.31|KEGG_REACTION:R00345 go-plus.json PEP carboxylase activity|phosphate:oxaloacetate carboxy-lyase (phosphorylating)|PEPC|PEPCase activity|phosphoenolpyruvic carboxylase activity|phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)|phosphopyruvate (phosphate) carboxylase activity http://purl.obolibrary.org/obo/GO_0008964 GO:0033920 biolink:MolecularActivity 6-phospho-beta-galactosidase activity Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol. EC:3.2.1.85|RHEA:24568|MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN go-plus.json phospho-beta-D-galactosidase activity|phospho-beta-galactosidase activity|6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity|6-phospho-beta-D-galactosidase activity|beta-D-phosphogalactoside galactohydrolase activity http://purl.obolibrary.org/obo/GO_0033920 OBO:GOCHE_35195 biolink:OntologyClass substance with surfactant role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35195 3_STAR GO:0008963 biolink:MolecularActivity phospho-N-acetylmuramoyl-pentapeptide-transferase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol. EC:2.7.8.13|MetaCyc:RXN-8975|RHEA:21920 go-plus.json UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity|UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity|UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity|phosphoacetylmuramoylpentapeptide translocase activity|phosphoacetylmuramoylpentapeptidetransferase activity|UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity|MraY transferase activity|phospho-N-acetylmuramoyl pentapeptide translocase activity|UDP-MurNAc-pentapeptide phosphotransferase activity|phospho-MurNAc-pentapeptide transferase activity http://purl.obolibrary.org/obo/GO_0008963 goslim_chembl GO:0043299 biolink:BiologicalProcess leukocyte degranulation The regulated exocytosis of secretory granules by a leukocyte. go-plus.json immune cell degranulation|immune cell granule exocytosis|leucocyte degranulation|leukocyte granule exocytosis http://purl.obolibrary.org/obo/GO_0043299 GO:0008962 biolink:MolecularActivity phosphatidylglycerophosphatase activity Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate. MetaCyc:PGPPHOSPHA-RXN|Reactome:R-HSA-1483197|EC:3.1.3.27|RHEA:16725 go-plus.json PGP phosphatase activity|phosphatidylglycerol phosphate phosphatase activity|phosphatidylglycerol phosphatase activity|phosphatidylglycerophosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008962 GO:0008961 biolink:MolecularActivity phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein. EC:2.5.1.145|RHEA:56712 go-plus.json http://purl.obolibrary.org/obo/GO_0008961 GO:0008960 biolink:MolecularActivity phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose. EC:2.7.8.20|MetaCyc:PGLYCEROLTRANSI-RXN go-plus.json oligosaccharide glycerophosphotransferase activity|phosphoglycerol transferase activity|phosphoglycerol transferase I|phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity http://purl.obolibrary.org/obo/GO_0008960 GO:0043296 biolink:CellularComponent apical junction complex A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. go-plus.json apical junction|apical cell junction complex http://purl.obolibrary.org/obo/GO_0043296 GO:0043295 biolink:MolecularActivity glutathione binding Binding to glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine. go-plus.json http://purl.obolibrary.org/obo/GO_0043295 GO:0043298 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043298 GO:0033929 biolink:MolecularActivity blood-group-substance endo-1,4-beta-galactosidase activity Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances. MetaCyc:3.2.1.102-RXN|EC:3.2.1.102 go-plus.json endo-beta-galactosidase activity|blood-group-substance 1,4-beta-D-galactanohydrolase activity http://purl.obolibrary.org/obo/GO_0033929 GO:0033928 biolink:MolecularActivity mannan 1,4-mannobiosidase activity Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends. MetaCyc:3.2.1.100-RXN|EC:3.2.1.100 go-plus.json 1,4-beta-D-mannan mannobiohydrolase activity|exo-beta-mannanase activity|exo-1,4-beta-mannobiohydrolase activity|mannan 1,4-beta-mannobiosidase activity http://purl.obolibrary.org/obo/GO_0033928 GO:0043297 biolink:BiologicalProcess apical junction assembly The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. go-plus.json apical junction complex assembly http://purl.obolibrary.org/obo/GO_0043297 CHEBI:58772 biolink:ChemicalSubstance L-methionine (S)-S-oxide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58772 chebi_ph7_3 CHEBI:58771 biolink:ChemicalSubstance (R)-2-(carboxylatomethyl)-5-oxo-2,5-dihydro-2-furoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58771 chebi_ph7_3 CHEBI:58770 biolink:ChemicalSubstance N-acetyl-alpha-neuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58770 chebi_ph7_3 CHEBI:58779 biolink:ChemicalSubstance CDP-choline(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58779 chebi_ph7_3 UBERON:0005515 biolink:AnatomicalEntity rhombomere 5 the fifth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r5 http://purl.obolibrary.org/obo/UBERON_0005515 CHEBI:58778 biolink:ChemicalSubstance 6-(2-azaniumyl-2-carboxylatoethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58778 chebi_ph7_3 CHEBI:58777 biolink:ChemicalSubstance 2-hydroxymethylglutarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58777 chebi_ph7_3 CHEBI:19168 biolink:ChemicalSubstance 17-oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19168 CHEBI:58776 biolink:ChemicalSubstance 2-formylglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58776 chebi_ph7_3 CHEBI:58775 biolink:ChemicalSubstance 3-oxo-3-ureidopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58775 chebi_ph7_3 UBERON:0005511 biolink:AnatomicalEntity rhombomere 4 the fourth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r4 http://purl.obolibrary.org/obo/UBERON_0005511 CHEBI:58774 biolink:ChemicalSubstance 3-dehydro-L-gulonate 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58774 chebi_ph7_3 CHEBI:58773 biolink:ChemicalSubstance L-methionine (R)-S-oxide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58773 chebi_ph7_3 CHEBI:44120 biolink:ChemicalSubstance L-methionine (S)-S-oxide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_44120 chebi_ph7_3 GO:0033916 biolink:MolecularActivity beta-agarase activity Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product. EC:3.2.1.81 go-plus.json agarose 4-glycanohydrolase activity|agarose 3-glycanohydrolase activity|agarase activity|AgaB|AgaA http://purl.obolibrary.org/obo/GO_0033916 GO:0033915 biolink:MolecularActivity mannan 1,2-(1,3)-alpha-mannosidase activity Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose. MetaCyc:3.2.1.77-RXN|EC:3.2.1.77 go-plus.json exo-1,2-1,3-alpha-mannosidase activity|1,2-1,3-alpha-D-mannan mannohydrolase activity http://purl.obolibrary.org/obo/GO_0033915 GO:0033914 biolink:MolecularActivity xylan 1,3-beta-xylosidase activity Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans. MetaCyc:3.2.1.72-RXN|EC:3.2.1.72 go-plus.json exo-beta-1,3'-xylanase activity|1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity|1,3-beta-D-xylan xylohydrolase activity|beta-1,3'-xylanase activity|exo-1,3-beta-xylosidase activity http://purl.obolibrary.org/obo/GO_0033914 GO:0033913 biolink:MolecularActivity glucan endo-1,2-beta-glucosidase activity Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans. MetaCyc:3.2.1.71-RXN|EC:3.2.1.71 go-plus.json endo-(1->2)-beta-D-glucanase activity|beta-D-1,2-glucanase activity|1,2-beta-D-glucan glucanohydrolase activity|endo-1,2-beta-glucanase activity http://purl.obolibrary.org/obo/GO_0033913 GO:0008979 biolink:MolecularActivity prophage integrase activity Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA. go-plus.json integrase activity involved in establishment of integrated proviral latency http://purl.obolibrary.org/obo/GO_0008979 GO:0033912 biolink:MolecularActivity 2,6-beta-fructan 6-levanbiohydrolase activity Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain. MetaCyc:3.2.1.64-RXN|EC:3.2.1.64 go-plus.json levanbiose-producing levanase activity|2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity|beta-2,6-fructan-6-levanbiohydrolase activity|2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity|2,6-beta-D-fructan 6-levanbiohydrolase activity http://purl.obolibrary.org/obo/GO_0033912 GO:0008978 biolink:MolecularActivity obsolete prepilin peptidase activity OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine. go-plus.json prepilin peptidase activity http://purl.obolibrary.org/obo/GO_0008978 GO:0033911 biolink:MolecularActivity mycodextranase activity Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds. MetaCyc:3.2.1.61-RXN|EC:3.2.1.61 go-plus.json 1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity http://purl.obolibrary.org/obo/GO_0033911 GO:0008977 biolink:MolecularActivity prephenate dehydrogenase (NAD+) activity Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH. KEGG_REACTION:R01728|MetaCyc:PREPHENATEDEHYDROG-RXN|EC:1.3.1.12|RHEA:13869 go-plus.json prephenate:NAD+ oxidoreductase (decarboxylating)|hydroxyphenylpyruvate synthase activity|chorismate mutase--prephenate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008977 GO:0033910 biolink:MolecularActivity glucan 1,4-alpha-maltotetraohydrolase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends. MetaCyc:3.2.1.60-RXN|EC:3.2.1.60 go-plus.json G4-amylase activity|glucan 1,4-alpha-maltotetrahydrolase activity|exo-maltotetraohydrolase activity|1,4-alpha-D-glucan maltotetraohydrolase activity|maltotetraose-forming amylase activity http://purl.obolibrary.org/obo/GO_0033910 GO:0008976 biolink:MolecularActivity polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1). MetaCyc:POLYPHOSPHATE-KINASE-RXN|EC:2.7.4.1|RHEA:19573 go-plus.json polyphosphoric acid kinase activity|ATP-polyphosphate phosphotransferase activity|ATP:polyphosphate phosphotransferase activity|polyphosphate polymerase activity http://purl.obolibrary.org/obo/GO_0008976 GO:0008975 biolink:MolecularActivity obsolete pitrilysin activity OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon. go-plus.json Escherichia coli metalloproteinase Pi|Escherichia coli protease III|pitrilysin activity|protease III activity|PTR|protease Pi activity|proteinase Pi http://purl.obolibrary.org/obo/GO_0008975 GO:0008974 biolink:MolecularActivity phosphoribulokinase activity Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+). MetaCyc:PHOSPHORIBULOKINASE-RXN|EC:2.7.1.19|KEGG_REACTION:R01523|RHEA:19365 go-plus.json PRuK|phosphoribulokinase (phosphorylating)|phosphopentokinase activity|PKK|5-phosphoribulose kinase activity|ribulose phosphate kinase activity|PRK|ribulose-5-phosphate kinase activity|ATP:D-ribulose-5-phosphate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008974 GO:0008973 biolink:MolecularActivity phosphopentomutase activity Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate. MetaCyc:PPENTOMUT-RXN|Reactome:R-HSA-8982667|EC:5.4.2.7|Reactome:R-HSA-6787329|RHEA:18793 go-plus.json deoxyribomutase activity|alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity|alpha-D-ribose 1,5-phosphomutase activity|phosphodeoxyribomutase activity|phosphoribomutase activity|deoxyribose phosphomutase activity|D-ribose 1,5-phosphomutase activity http://purl.obolibrary.org/obo/GO_0008973 GO:0008972 biolink:MolecularActivity phosphomethylpyrimidine kinase activity Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine. EC:2.7.4.7|RHEA:19893|MetaCyc:PYRIMSYN3-RXN go-plus.json ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity|hydroxymethylpyrimidine phosphokinase activity http://purl.obolibrary.org/obo/GO_0008972 GO:0008971 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008971 GO:0008970 biolink:MolecularActivity phospholipase A1 activity Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate. EC:3.1.1.32|MetaCyc:PHOSPHOLIPASE-A1-RXN|Reactome:R-HSA-1482847|Reactome:R-HSA-5694485|Reactome:R-HSA-1482920|RHEA:18689|Reactome:R-HSA-1482932|Reactome:R-HSA-1482862|Reactome:R-HSA-1482827|Reactome:R-HSA-1482892|Reactome:R-HSA-1482828 go-plus.json phosphatidylcholine 1-acylhydrolase activity http://purl.obolibrary.org/obo/GO_0008970 goslim_chembl GO:0033919 biolink:MolecularActivity glucan 1,3-alpha-glucosidase activity Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans. Reactome:R-HSA-532667|Reactome:R-HSA-9683663|Reactome:R-HSA-548890|MetaCyc:3.2.1.84-RXN|Reactome:R-HSA-9694364|EC:3.2.1.84 go-plus.json 1,3-alpha-D-glucan 3-glucohydrolase activity|exo-1,3-alpha-glucanase activity|glucosidase II activity http://purl.obolibrary.org/obo/GO_0033919 GO:0033918 biolink:MolecularActivity kappa-carrageenase activity Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans. MetaCyc:3.2.1.83-RXN|EC:3.2.1.83 go-plus.json kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity|kappa-carrageenan 4-beta-D-glycanohydrolase activity http://purl.obolibrary.org/obo/GO_0033918 GO:0033917 biolink:MolecularActivity exo-poly-alpha-galacturonosidase activity Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate. MetaCyc:3.2.1.82-RXN|EC:3.2.1.82|RHEA:56232 go-plus.json exopolygalacturonosidase activity|exopolygalacturanosidase activity http://purl.obolibrary.org/obo/GO_0033917 OBO:GOREL_0012006 biolink:OntologyClass results_in_maintenance_of GOREL:0012006 go-plus.json http://purl.obolibrary.org/obo/GOREL_0012006 CHEBI:58761 biolink:ChemicalSubstance L-2,4-diazaniumylbutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58761 chebi_ph7_3 CHEBI:58760 biolink:ChemicalSubstance demethylsulochrin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58760 CHEBI:2106 biolink:ChemicalSubstance 5-[(E)-caffeoyl]shikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2106 CHEBI:58769 biolink:ChemicalSubstance (S)-1-piperideine-6-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58769 chebi_ph7_3 CHEBI:58768 biolink:ChemicalSubstance (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58768 chebi_ph7_3 CHEBI:58767 biolink:ChemicalSubstance N-acetyl-LL-2,6-diaminopimelate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58767 chebi_ph7_3 CHEBI:58766 biolink:ChemicalSubstance 4-O-phosphonato-D-erythronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58766 chebi_ph7_3 UBERON:0005502 biolink:AnatomicalEntity rhombomere roof plate go-plus.json roof plate hindbrain|future hindbrain roof plate|roof plate rhombomere|roof plate rhombomere region|roof plate rhombomeres http://purl.obolibrary.org/obo/UBERON_0005502 UBERON:0005501 biolink:AnatomicalEntity rhombomere lateral wall A neural tube lateral wall that is part of a rhombomere. go-plus.json future hindbrain lateral wall http://purl.obolibrary.org/obo/UBERON_0005501 CHEBI:58765 biolink:ChemicalSubstance N-acetyl-L-citrullinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58765 chebi_ph7_3 CHEBI:58764 biolink:ChemicalSubstance (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58764 chebi_ph7_3 CHEBI:58763 biolink:ChemicalSubstance N-(3-carboxylatopropanoyl)-L-glutamate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58763 chebi_ph7_3 CHEBI:58762 biolink:ChemicalSubstance 7,8-dihydroneopterin 3'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58762 chebi_ph7_3 GO:0033905 biolink:MolecularActivity xylan endo-1,3-beta-xylosidase activity Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans. EC:3.2.1.32|MetaCyc:3.2.1.32-RXN go-plus.json endo-beta-1,3-xylanase activity|xylanase activity|1,3-beta-xylanase activity|1,3-beta-D-xylan xylanohydrolase activity|endo-1,3-xylanase activity|endo-1,3-beta-xylanase activity|beta-1,3-xylanase activity|1,3-xylanase activity http://purl.obolibrary.org/obo/GO_0033905 GO:0008949 biolink:MolecularActivity oxalyl-CoA decarboxylase activity Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA. EC:4.1.1.8|RHEA:19333|KEGG_REACTION:R01908|MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN go-plus.json oxalyl-CoA carboxy-lyase (formyl-CoA-forming)|oxalyl-CoA carboxy-lyase activity|oxalyl coenzyme A decarboxylase activity http://purl.obolibrary.org/obo/GO_0008949 GO:0033904 biolink:MolecularActivity dextranase activity Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran. EC:3.2.1.11|MetaCyc:3.2.1.11-RXN go-plus.json 1,6-alpha-D-glucan 6-glucanohydrolase activity|DL 2|dextran hydrolase activity|dextranase DL 2 activity|alpha-D-1,6-glucan-6-glucanohydrolase activity|endodextranase activity|endo-dextranase activity|alpha-1,6-glucan-6-glucanohydrolase activity http://purl.obolibrary.org/obo/GO_0033904 GO:0008948 biolink:MolecularActivity oxaloacetate decarboxylase activity Catalysis of the reaction: oxaloacetate = pyruvate + CO2. RHEA:15641|EC:4.1.1.112|EC:1.1.1.38|MetaCyc:OXALODECARB-RXN|Reactome:R-HSA-9012016|KEGG_REACTION:R00217|EC:1.1.1.40 go-plus.json oxalate beta-decarboxylase activity|oxalacetic acid decarboxylase activity|oxaloacetate carboxy-lyase (pyruvate-forming)|oxaloacetate carboxy-lyase activity|oxaloacetate beta-decarboxylase activity http://purl.obolibrary.org/obo/GO_0008948 GO:0008947 biolink:MolecularActivity obsolete omptin activity OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys. go-plus.json omptin activity http://purl.obolibrary.org/obo/GO_0008947 GO:0033903 biolink:MolecularActivity obsolete endo-1,3(4)-beta-glucanase activity OBSOLETE. Catalysis of the endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3. MetaCyc:3.2.1.6-RXN|EC:3.2.1.6 go-plus.json laminaranase activity|endo-1,3-beta-D-glucanase activity|laminarinase activity|endo-beta-1,3-1,4-glucanase activity|beta-1,3-glucanase activity|endo-1,4-beta-glucanase activity|1,3-(1,3;1,4)-beta-D-glucan 3(4)-glucanohydrolase activity|endo-1,3-beta-glucanase activity|endo-1,3(4)-beta-glucanase activity|beta-1,3-1,4-glucanase activity|endo-beta-1,3(4)-glucanase activity|endo-1,3-1,4-beta-D-glucanase activity|endo-beta-1,3-glucanase IV activity|endo-beta-(1->3)-D-glucanase activity|endo-beta-(1,3)-D-glucanase activity http://purl.obolibrary.org/obo/GO_0033903 GO:0008946 biolink:MolecularActivity oligonucleotidase activity Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates. MetaCyc:3.1.13.3-RXN|EC:3.1.13.3 go-plus.json http://purl.obolibrary.org/obo/GO_0008946 GO:0033902 biolink:MolecularActivity rRNA endonuclease activity Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes. EC:4.6.1.23|MetaCyc:3.1.27.10-RXN go-plus.json alpha-sarcin http://purl.obolibrary.org/obo/GO_0033902 GO:0033901 biolink:MolecularActivity ribonuclease V activity Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP. MetaCyc:3.1.27.8-RXN|EC:3.1.27.8 go-plus.json endoribonuclease V activity http://purl.obolibrary.org/obo/GO_0033901 GO:0008945 biolink:MolecularActivity obsolete oligopeptidase B activity OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline. go-plus.json oligopeptidase B activity|protease II activity|Escherichia coli alkaline proteinase II http://purl.obolibrary.org/obo/GO_0008945 GO:0033900 biolink:MolecularActivity ribonuclease F activity Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups. MetaCyc:3.1.27.7-RXN|EC:3.1.27.7 go-plus.json ribonuclease F (E. coli) activity|RNase F activity http://purl.obolibrary.org/obo/GO_0033900 GO:0008944 biolink:MolecularActivity obsolete oligopeptidase A activity OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5. go-plus.json oligopeptidase A activity|68000-M signalpeptide hydrolase activity http://purl.obolibrary.org/obo/GO_0008944 GO:0008943 biolink:MolecularActivity obsolete glyceraldehyde-3-phosphate dehydrogenase activity OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+. go-plus.json glyceraldehyde-3-phosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008943 GO:0008942 biolink:MolecularActivity nitrite reductase [NAD(P)H] activity Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+. EC:1.7.1.4|MetaCyc:NITRITREDUCT-RXN|KEGG_REACTION:R00789|KEGG_REACTION:R00787 go-plus.json nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NAD(P)H2:nitrite oxidoreductase activity|NAD(P)H:nitrite oxidoreductase activity|assimilatory nitrite reductase activity|NADPH-nitrite reductase activity|ammonium-hydroxide:NAD(P)+ oxidoreductase activity|nitrite reductase [NAD(P)H2]|NADH-nitrite oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008942 CHEBI:58759 biolink:ChemicalSubstance 6-phosphonatooxy-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58759 chebi_ph7_3 GO:0008941 biolink:MolecularActivity nitric oxide dioxygenase activity Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+. Reactome:R-HSA-1222723|EC:1.14.12.17|Reactome:R-HSA-5340226|MetaCyc:R621-RXN go-plus.json nitric oxide,NAD(P)H:oxygen oxidoreductase activity|NOD activity http://purl.obolibrary.org/obo/GO_0008941 GO:0008940 biolink:MolecularActivity nitrate reductase activity Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor. EC:1.7.99.4|MetaCyc:NITRATREDUCT-RXN|RHEA:21068 go-plus.json nitrite:acceptor oxidoreductase|nitrite:(acceptor) oxidoreductase|nitrate reductase (acceptor)|respiratory nitrate reductase activity http://purl.obolibrary.org/obo/GO_0008940 GO:0033909 biolink:MolecularActivity fucoidanase activity Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate. MetaCyc:RXN-20949|EC:3.2.1.211 go-plus.json poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity http://purl.obolibrary.org/obo/GO_0033909 GO:0033908 biolink:MolecularActivity beta-L-rhamnosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides. EC:3.2.1.43|MetaCyc:3.2.1.43-RXN go-plus.json beta-L-rhamnoside rhamnohydrolase activity http://purl.obolibrary.org/obo/GO_0033908 GO:0033907 biolink:MolecularActivity beta-D-fucosidase activity Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides. EC:3.2.1.38|MetaCyc:3.2.1.38-RXN go-plus.json beta-D-fucoside fucohydrolase activity|beta-fucosidase activity http://purl.obolibrary.org/obo/GO_0033907 CHEBI:20140 biolink:ChemicalSubstance 3-methylquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_20140 chebi_ph7_3 CHEBI:44111 biolink:ChemicalSubstance 3-mercaptopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44111 GO:0033906 biolink:MolecularActivity hyaluronoglucuronidase activity Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate. EC:3.2.1.36|MetaCyc:3.2.1.36-RXN go-plus.json glucuronoglucosaminoglycan hyaluronate lyase activity|hyaluronate 3-glycanohydrolase activity|hyaluronidase activity|orgelase activity http://purl.obolibrary.org/obo/GO_0033906 CHEBI:58750 biolink:ChemicalSubstance (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58750 chebi_ph7_3 CHEBI:34784 biolink:ChemicalSubstance hepoxilin B3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_34784 CHEBI:34787 biolink:ChemicalSubstance heptanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_34787 chebi_ph7_3 CHEBI:58758 biolink:ChemicalSubstance S-(hydroxymethyl)glutathione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58758 chebi_ph7_3 CHEBI:58757 biolink:ChemicalSubstance (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58757 chebi_ph7_3 CHEBI:58756 biolink:ChemicalSubstance 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58756 chebi_ph7_3 CHEBI:58754 biolink:ChemicalSubstance pGpG(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58754 chebi_ph7_3 CHEBI:58753 biolink:ChemicalSubstance ADP-D-ribose 1''-phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58753 chebi_ph7_3 CHEBI:58752 biolink:ChemicalSubstance (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58752 chebi_ph7_3 GO:0008959 biolink:MolecularActivity phosphate acetyltransferase activity Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate. MetaCyc:PHOSACETYLTRANS-RXN|EC:2.3.1.8|RHEA:19521 go-plus.json phosphotransacetylase activity|phosphoacylase activity|PTA|acetyl-CoA:phosphate acetyltransferase activity http://purl.obolibrary.org/obo/GO_0008959 GO:0008958 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008958 GO:0008957 biolink:MolecularActivity phenylacetaldehyde dehydrogenase activity Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+. MetaCyc:PHENDEHYD-RXN|EC:1.2.1.39|UM-BBD_reactionID:r0035|RHEA:21392 go-plus.json phenylacetaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008957 GO:0008956 biolink:MolecularActivity obsolete peptidyl-dipeptidase Dcp activity OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly. MetaCyc:3.4.15.5-RXN|EC:3.4.15.5 go-plus.json dipeptidyl carboxypeptidase activity|peptidyl-dipeptidase Dcp activity|dipeptidyl carboxypeptidase (Dcp) http://purl.obolibrary.org/obo/GO_0008956 GO:0008955 biolink:MolecularActivity peptidoglycan glycosyltransferase activity Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate. MetaCyc:RXN0-5405|RHEA:23708|EC:2.4.1.129 go-plus.json peptidoglycan TGase activity|penicillin binding protein (3 or 1B) activity|undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity|peptidoglycan transglycosylase activity|bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity|PG-II activity http://purl.obolibrary.org/obo/GO_0008955 CHEBI:20156 biolink:ChemicalSubstance 3-oxo-Delta(1) steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20156 chebi_ph7_3 GO:0008954 biolink:MolecularActivity obsolete peptidoglycan synthetase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json peptidoglycan synthetase activity http://purl.obolibrary.org/obo/GO_0008954 CHEBI:58749 biolink:ChemicalSubstance 5-deoxy-alpha-D-ribose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58749 chebi_ph7_3 GO:0008953 biolink:MolecularActivity penicillin amidase activity Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate. EC:3.5.1.11|MetaCyc:PENICILLIN-AMIDASE-RXN|RHEA:18693 go-plus.json penicillin amidohydrolase activity|penicillin acylase activity|benzylpenicillin acylase activity|alpha-acylamino-beta-lactam acylhydrolase activity|novozym 217|semacylase activity|palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity|ampicillin acylase activity http://purl.obolibrary.org/obo/GO_0008953 CHEBI:58748 biolink:ChemicalSubstance N-iminiumylmethyl-L-aspartate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58748 chebi_ph7_3 GO:0008952 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008952 GO:0008951 biolink:MolecularActivity palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein]. RHEA:44012|MetaCyc:PALMITOTRANS-RXN go-plus.json palmitoleoyl ACP-dependent acyltransferase activity http://purl.obolibrary.org/obo/GO_0008951 GO:0008950 biolink:MolecularActivity obsolete p-aminobenzoate synthetase OBSOLETE. (Was not defined before being made obsolete). go-plus.json p-aminobenzoate synthetase http://purl.obolibrary.org/obo/GO_0008950 CHEBI:58747 biolink:ChemicalSubstance 1D-myo-inositol 1,2,3,5,6-pentakisphosphate(10-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58747 chebi_ph7_3 CHEBI:58746 biolink:ChemicalSubstance UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58746 chebi_ph7_3 CHEBI:58745 biolink:ChemicalSubstance UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58745 chebi_ph7_3 CHEBI:58744 biolink:ChemicalSubstance 3-(3,4-dihydroxyphenyl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58744 chebi_ph7_3 CHEBI:58743 biolink:ChemicalSubstance 13(2)-carboxypyropheophorbide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58743 chebi_ph7_3 CHEBI:58742 biolink:ChemicalSubstance pyropheophorbide a anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58742 chebi_ph7_3 CHEBI:58741 biolink:ChemicalSubstance 7(1)-hydroxychlorophyllide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58741 GO:0008927 biolink:MolecularActivity mannonate dehydratase activity Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O. KEGG_REACTION:R05606|EC:4.2.1.8|RHEA:20097|MetaCyc:MANNONDEHYDRAT-RXN go-plus.json D-mannonate hydrolyase activity|altronate hydrolase activity|mannonic hydrolase activity|altronic hydro-lyase activity|D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)|mannonate hydrolyase activity|D-mannonate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0008927 GO:0008926 biolink:MolecularActivity mannitol-1-phosphate 5-dehydrogenase activity Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+. RHEA:19661|MetaCyc:MANNPDEHYDROG-RXN|EC:1.1.1.17 go-plus.json http://purl.obolibrary.org/obo/GO_0008926 GO:0008925 biolink:MolecularActivity maltose O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose. RHEA:10456|MetaCyc:MALTACETYLTRAN-RXN|EC:2.3.1.79 go-plus.json acetyl-CoA:maltose O-acetyltransferase activity|maltose transacetylase activity http://purl.obolibrary.org/obo/GO_0008925 GO:0008924 biolink:MolecularActivity malate dehydrogenase (quinone) activity Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol. RHEA:22556|EC:1.1.5.4|MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN go-plus.json (S)-malate:quinone oxidoreductase activity|(S)-malate:(quinone) oxidoreductase activity|FAD-dependent malate dehydrogenase activity|MQO activity http://purl.obolibrary.org/obo/GO_0008924 GO:0008923 biolink:MolecularActivity lysine decarboxylase activity Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2). KEGG_REACTION:R00462|RHEA:22352|MetaCyc:LYSDECARBOX-RXN|EC:4.1.1.18|MetaCyc:PWY0-461 go-plus.json L-lysine carboxy-lyase activity|L-lysine carboxy-lyase (cadaverine-forming) http://purl.obolibrary.org/obo/GO_0008923 GO:0008922 biolink:MolecularActivity long-chain fatty acid [acyl-carrier-protein] ligase activity Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22. RHEA:45588|EC:6.2.1.20|KEGG_REACTION:R07325|MetaCyc:ACYLACPSYNTH-RXN go-plus.json long-chain fatty acid-[acyl-carrier-protein] ligase activity|long-chain-fatty-acid-ACP ligase activity|acyl-[acyl-carrier-protein] synthetase activity|long-chain-fatty-acid-[acyl-carrier protein] ligase activity|long-chain-fatty-acid-acyl-carrier-protein ligase activity|acyl-ACP synthetase activity|acyl-acyl carrier protein synthetase|acyl-acyl-carrier-proteinsynthetase activity|acyl-acyl-carrier-protein synthetase activity|stearoyl-ACP synthetase activity|long-chain-fatty-acid-[acyl-carrier-protein] ligase activity|long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity http://purl.obolibrary.org/obo/GO_0008922 CHEBI:58739 biolink:ChemicalSubstance 2-aminobut-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58739 GO:0008921 biolink:MolecularActivity lipopolysaccharide-1,6-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide. go-plus.json LPS-1,6-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0008921 CHEBI:58738 biolink:ChemicalSubstance (R)-3-sulfolactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58738 chebi_ph7_3 GO:0008920 biolink:MolecularActivity lipopolysaccharide heptosyltransferase activity Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+. go-plus.json LPS heptosyltransferase activity http://purl.obolibrary.org/obo/GO_0008920 CHEBI:58737 biolink:ChemicalSubstance (R)-2-O-sulfonatolactate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58737 chebi_ph7_3 CHEBI:34768 biolink:ChemicalSubstance furfural go-plus.json http://purl.obolibrary.org/obo/CHEBI_34768 chebi_ph7_3 OBO:GOCHE_50790 biolink:OntologyClass substance with EC 1.14.14.14 (aromatase) inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50790 3_STAR NCBITaxon:307596 biolink:OrganismalEntity Gloeobacteria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_307596 NCBITaxon:307595 biolink:OrganismalEntity Gloeobacterales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_307595 CHEBI:19129 biolink:ChemicalSubstance 11alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19129 CHEBI:58736 biolink:ChemicalSubstance (S)-5-oxo-2,5-dihydro-2-furylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58736 chebi_ph7_3 CHEBI:58735 biolink:ChemicalSubstance D-mannopyranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58735 chebi_ph7_3 CHEBI:58734 biolink:ChemicalSubstance (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58734 chebi_ph7_3 CHEBI:58733 biolink:ChemicalSubstance 4-methylene-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58733 chebi_ph7_3 CHEBI:58732 biolink:ChemicalSubstance N-[(E)-4-ammoniobutylidene]propane-1,3-diaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58732 chebi_ph7_3 CHEBI:10790 biolink:ChemicalSubstance methylenediurea go-plus.json http://purl.obolibrary.org/obo/CHEBI_10790 chebi_ph7_3 CHEBI:58731 biolink:ChemicalSubstance gamma-L-glutamylputrescinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58731 chebi_ph7_3 GO:0008929 biolink:MolecularActivity methylglyoxal synthase activity Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate. RHEA:17937|KEGG_REACTION:R01016|MetaCyc:METHGLYSYN-RXN|EC:4.2.3.3 go-plus.json glycerone-phosphate phospho-lyase (methylglyoxal-forming)|glycerone-phosphate phospho-lyase activity|methylglyoxal synthetase activity http://purl.obolibrary.org/obo/GO_0008929 CHEBI:58730 biolink:ChemicalSubstance 5-carboxylatoamino-1-(5-O-phosphonato-D-ribosyl)imidazole(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58730 chebi_ph7_3 GO:0008928 biolink:MolecularActivity mannose-1-phosphate guanylyltransferase (GDP) activity Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate. KEGG_REACTION:R00883|MetaCyc:MANNPGUANYLTRANGDP-RXN|EC:2.7.7.22|RHEA:12905 go-plus.json guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity|GDP:mannose-1-phosphate guanylyltransferase activity|GDP mannose phosphorylase activity|GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity|mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity|mannose 1-phosphate guanylyltransferase activity|GDP-mannose pyrophosphorylase activity|GDP:D-mannose-1-phosphate guanylyltransferase activity|GDP-mannose phosphorylase activity|GDP-mannose 1-phosphate guanylyltransferase activity|guanosine diphosphomannose phosphorylase activity http://purl.obolibrary.org/obo/GO_0008928 GO:0008938 biolink:MolecularActivity nicotinate N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine. KEGG_REACTION:R01721|MetaCyc:NICOTINATE-N-METHYLTRANSFERASE-RXN|RHEA:20241|EC:2.1.1.7 go-plus.json S-adenosyl-L-methionine:nicotinate N-methyltransferase activity|furanocoumarin 8-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008938 GO:0008937 biolink:MolecularActivity ferredoxin-NAD(P) reductase activity Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+. go-plus.json ferredoxin reductase activity http://purl.obolibrary.org/obo/GO_0008937 GO:0008936 biolink:MolecularActivity nicotinamidase activity Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3. EC:3.5.1.19|RHEA:14545|MetaCyc:NICOTINAMID-RXN go-plus.json nicotinamide deaminase activity|nicotinamide amidase activity|NAMase activity|nicotine deamidase activity|nicotinamide amidohydrolase activity|YNDase activity http://purl.obolibrary.org/obo/GO_0008936 GO:0008935 biolink:MolecularActivity 1,4-dihydroxy-2-naphthoyl-CoA synthase activity Catalysis of the reaction: 2-succinylbenzoyl-CoA + H+ = 1,4-dihydroxy-2-naphthoyl-CoA + H2O. EC:4.1.3.36|RHEA:26562|MetaCyc:NAPHTHOATE-SYN-RXN|KEGG_REACTION:R04150 go-plus.json DHNA synthetase activity|naphthoate synthase activity|O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity|dihydroxynaphthoic acid synthetase activity|dihydroxynaphthoate synthase activity http://purl.obolibrary.org/obo/GO_0008935 GO:0008934 biolink:MolecularActivity inositol monophosphate 1-phosphatase activity Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate. MetaCyc:RXN0-5408|EC:3.1.3.25|Reactome:R-HSA-1855154|RHEA:27670 go-plus.json myo-inositol-1(or 4)-monophosphatase activity|myo-inositol 1-phosphatase activity|L-myo-inositol-1-phosphate phosphatase activity|myo-inositol-1-phosphatase activity|inositol 1-phosphatase activity|inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008934 CHEBI:58729 biolink:ChemicalSubstance N,N-dihydroxy-L-tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58729 chebi_ph7_3 GO:0008933 biolink:MolecularActivity lytic transglycosylase activity Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. EC:3.2.1.- go-plus.json murein transglycosylase B activity|peptidoglycan lytic transglycosylase activity http://purl.obolibrary.org/obo/GO_0008933 CHEBI:58728 biolink:ChemicalSubstance N-hydroxy-L-tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58728 chebi_ph7_3 GO:0008932 biolink:MolecularActivity lytic endotransglycosylase activity Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends. EC:2.4.99.- go-plus.json murein lytic endotransglycosylase E activity http://purl.obolibrary.org/obo/GO_0008932 CHEBI:58727 biolink:ChemicalSubstance N,N-dihydroxy-L-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58727 chebi_ph7_3 GO:0008931 biolink:MolecularActivity obsolete murein DD-endopeptidase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json murein DD-endopeptidase activity http://purl.obolibrary.org/obo/GO_0008931 CHEBI:58726 biolink:ChemicalSubstance N-hydroxy-L-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58726 chebi_ph7_3 GO:0008930 biolink:MolecularActivity methylthioadenosine nucleosidase activity Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose. EC:3.2.2.16|RHEA:13617|MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN go-plus.json MeSAdo nucleosidase activity|methylthioadenosine methylthioribohydrolase activity|S-methyl-5'-thioadenosine adeninehyrolase activity|5'-methylthioadenosine nucleosidase activity|MTA nucleosidase activity http://purl.obolibrary.org/obo/GO_0008930 CHEBI:34779 biolink:ChemicalSubstance glyoxal go-plus.json http://purl.obolibrary.org/obo/CHEBI_34779 chebi_ph7_3 CHEBI:10782 biolink:ChemicalSubstance (S)-(-)-perillyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_10782 chebi_ph7_3 CHEBI:58725 biolink:ChemicalSubstance 2-ammonio-2-deoxy-D-glucopyranose 6-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58725 chebi_ph7_3 CHEBI:58724 biolink:ChemicalSubstance threo-3-methyl-L-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58724 chebi_ph7_3 CHEBI:58723 biolink:ChemicalSubstance 2-ammonio-2-deoxy-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_58723 chebi_ph7_3 CHEBI:58722 biolink:ChemicalSubstance N-acetylmuramate 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58722 chebi_ph7_3 CHEBI:58721 biolink:ChemicalSubstance N-acetyl-beta-muramate 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58721 chebi_ph7_3 CHEBI:58720 biolink:ChemicalSubstance D-glucopyranuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58720 chebi_ph7_3 GO:0008939 biolink:MolecularActivity nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate. EC:2.4.2.21|KEGG_REACTION:R04148|MetaCyc:DMBPPRIBOSYLTRANS-RXN|RHEA:11196 go-plus.json nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity|CobT|N(1)-alpha-phosphoribosyltransferase activity|nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity|nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity|N1-alpha-phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0008939 GO:0008905 biolink:MolecularActivity mannose-phosphate guanylyltransferase activity Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0008905 GO:0008904 biolink:MolecularActivity hygromycin-B 7''-O-phosphotransferase activity Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+). EC:2.7.1.119|RHEA:23388|KEGG_REACTION:R03770|MetaCyc:HYGROMYCIN-B-KINASE-RXN go-plus.json APH(7'') activity|hygromycin B kinase activity|ATP:hygromycin-B 7''-O-phosphotransferase activity|hygromycin B phosphotransferase activity|hygromycin-B kinase activity|destomic acid ring 7''-O-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008904 GO:0008903 biolink:MolecularActivity hydroxypyruvate isomerase activity Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate. RHEA:11952|EC:5.3.1.22|KEGG_REACTION:R01394|MetaCyc:RXN0-305 go-plus.json hydroxypyruvate ketol-isomerase activity|hydroxypyruvate aldose-ketose-isomerase activity http://purl.obolibrary.org/obo/GO_0008903 GO:0008902 biolink:MolecularActivity hydroxymethylpyrimidine kinase activity Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+). MetaCyc:OHMETPYRKIN-RXN|EC:2.7.1.49|KEGG_REACTION:R03471|RHEA:23096 go-plus.json ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity|hydroxymethylpyrimidine kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0008902 CHEBI:58719 biolink:ChemicalSubstance primary fluorescent chlorophyll catabolite(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58719 GO:0008901 biolink:MolecularActivity ferredoxin hydrogenase activity Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. EC:1.12.7.2|RHEA:17445|MetaCyc:HYDROG-RXN|UM-BBD_enzymeID:e0418 go-plus.json Ni-Fe-Se hydrogenase activity|hydrogenase (ferredoxin) activity|iron-only hydrogenase activity|hydrogenase activity|Ni-Fe hydrogenase activity|H2 producing hydrogenase|hydrogenase II|hydrogenlyase activity|H(2) producing hydrogenase activity|nickel-iron-selenium hydrogenase activity|hydrogen:ferredoxin oxidoreductase activity|H2 oxidizing hydrogenase|uptake hydrogenase activity|iron hydrogenase activity|[Fe] hydrogenase gamma|[Fe] hydrogenase activity|bidirectional hydrogenase activity|hydrogenase I|nickel hydrogenase activity|H(2) oxidizing hydrogenase activity|nickel-iron hydrogenase activity|hydrogen-lyase activity http://purl.obolibrary.org/obo/GO_0008901 CHEBI:58718 biolink:ChemicalSubstance S-substituted N-acetyl-L-cysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58718 chebi_ph7_3 GO:0008900 biolink:MolecularActivity P-type potassium:proton transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in). Reactome:R-HSA-937311|RHEA:22044|EC:7.2.2.19 go-plus.json H+/K+-ATPase activity|H(+)/K(+)-ATPase activity|H+-K+-ATPase activity|H,K-ATPase activity|proton pump activity|hydrogen:potassium-exchanging ATPase activity|potassium:proton exchanging ATPase activity|gastric H(+)/K(+) ATPase activity|hydrogen/potassium-exchanging ATPase activity|(K+ + H+)-ATPase activity|hydrogen:potassium exchanging ATPase activity|gastric H+/K+ ATPase|ATP phosphohydrolase (H+/K+-exchanging)|H(+)/K(+)-exchanging ATPase activity|H+/K+-exchanging ATPase activity http://purl.obolibrary.org/obo/GO_0008900 CHEBI:58717 biolink:ChemicalSubstance S-substituted L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58717 chebi_ph7_3 CHEBI:58716 biolink:ChemicalSubstance red chlorophyll catabolite(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58716 chebi_ph7_3 CHEBI:58715 biolink:ChemicalSubstance calcitroate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58715 chebi_ph7_3 CHEBI:58714 biolink:ChemicalSubstance beta-L-Ara4N-lipid A(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58714 chebi_ph7_3 CHEBI:58713 biolink:ChemicalSubstance 7-chloro-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58713 chebi_ph7_3 CHEBI:58712 biolink:ChemicalSubstance lipid A(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58712 chebi_ph7_3 CHEBI:58711 biolink:ChemicalSubstance 4-azaniumyl-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58711 chebi_ph7_3 GO:0008909 biolink:MolecularActivity isochorismate synthase activity Catalysis of the reaction: chorismate = isochorismate. KEGG_REACTION:R01717|EC:5.4.4.2|MetaCyc:ISOCHORSYN-RXN|RHEA:18985 go-plus.json isochorismate synthetase activity|isochorismate mutase activity|isochorismate hydroxymutase activity http://purl.obolibrary.org/obo/GO_0008909 CHEBI:58710 biolink:ChemicalSubstance UDP-beta-L-threo-pentopyranos-4-ulose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58710 chebi_ph7_3 GO:0008908 biolink:MolecularActivity isochorismatase activity Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate. KEGG_REACTION:R03037|RHEA:11112|EC:3.3.2.1|MetaCyc:ISOCHORMAT-RXN go-plus.json 2,3-dihydroxy-2,3-dihydrobenzoate synthase activity|2,3-dihydro-2,3-dihydroxybenzoate synthase activity|2,3 dihydro-2,3 dihydroxybenzoate synthase activity|isochorismate pyruvate-hydrolase activity|2,3-dihydroxy-2,3-dihydrobenzoic synthase activity http://purl.obolibrary.org/obo/GO_0008908 GO:0008907 biolink:MolecularActivity integrase activity Catalysis of the integration of one DNA segment into another. Reactome:R-HSA-164523 go-plus.json http://purl.obolibrary.org/obo/GO_0008907 goslim_pir GO:0008906 biolink:MolecularActivity inosine kinase activity Catalysis of the reaction: ATP + inosine = ADP + IMP. EC:2.7.1.73|MetaCyc:INOSINEKIN-RXN|RHEA:21140 go-plus.json ATP:inosine 5'-phosphotransferase activity|inosine kinase (phosphorylating)|inosine-guanosine kinase activity http://purl.obolibrary.org/obo/GO_0008906 GO:0008916 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008916 GO:0008915 biolink:MolecularActivity lipid-A-disaccharide synthase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP. EC:2.4.1.182|KEGG_REACTION:R04606|RHEA:22668|MetaCyc:LIPIDADISACCHARIDESYNTH-RXN go-plus.json UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0008915 GO:0008914 biolink:MolecularActivity leucyltransferase activity Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein. MetaCyc:LEUCYLTRANSFERASE-RXN|EC:2.3.2.6|RHEA:12340 go-plus.json leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity|leucyl, phenylalanine-tRNA-protein transferase activity|L-leucyl-tRNA:protein leucyltransferase activity|leucyl/phenylalanyl-tRNA--protein transferase activity|leucyl-tRNA--protein transferase activity|leucyl-phenylalanine-transfer ribonucleate-protein transferase activity|L/F transferase activity http://purl.obolibrary.org/obo/GO_0008914 CHEBI:58709 biolink:ChemicalSubstance UDP-4-deoxy-4-formamido-beta-L-arabinopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58709 chebi_ph7_3 GO:0008913 biolink:MolecularActivity lauroyltransferase activity Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another. go-plus.json lauroyl transferase activity http://purl.obolibrary.org/obo/GO_0008913 CHEBI:58708 biolink:ChemicalSubstance UDP-4-amino-4-deoxy-beta-L-arabinopyranose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58708 chebi_ph7_3 GO:0008912 biolink:MolecularActivity lactaldehyde reductase activity Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+. EC:1.1.1.77 go-plus.json (R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity|lactaldehyde:propanediol oxidoreductase activity|propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity|propanediol oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008912 CHEBI:58706 biolink:ChemicalSubstance L-methioninium (R)-S-oxide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_58706 chebi_ph7_3 GO:0008911 biolink:MolecularActivity lactaldehyde dehydrogenase activity Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+. MetaCyc:LACTALDDEHYDROG-RXN|EC:1.2.1.22|RHEA:14277 go-plus.json (S)-lactaldehyde:NAD+ oxidoreductase activity|L-lactaldehyde:NAD oxidoreductase activity|nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008911 UBERON:0005519 biolink:AnatomicalEntity rhombomere 6 the sixth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r6 http://purl.obolibrary.org/obo/UBERON_0005519 GO:0008910 biolink:MolecularActivity kanamycin kinase activity Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate. KEGG_REACTION:R01888|MetaCyc:KANAMYCIN-KINASE-RXN|RHEA:24256|EC:2.7.1.95 go-plus.json kanamycin kinase (phosphorylating)|ATP:kanamycin 3'-O-phosphotransferase activity|neomycin-kanamycin phosphotransferase activity|aminoglycoside 3'-phosphotransferase activity|neomycin phosphotransferase activity|APH(3') activity http://purl.obolibrary.org/obo/GO_0008910 CHEBI:58705 biolink:ChemicalSubstance N-acetyl-beta-neuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58705 chebi_ph7_3 CHEBI:58704 biolink:ChemicalSubstance 3,3,3-tetraminium(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58704 chebi_ph7_3 CHEBI:20114 biolink:ChemicalSubstance 3-methylquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_20114 chebi_ph7_3 UBERON:0005527 biolink:AnatomicalEntity rhombomere 8 the eighth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r8 http://purl.obolibrary.org/obo/UBERON_0005527 CHEBI:58703 biolink:ChemicalSubstance 7-ammoniomethyl-7-deazaguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58703 chebi_ph7_3 CHEBI:58702 biolink:ChemicalSubstance phosphonatoenolpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58702 chebi_ph7_3 CHEBI:19138 biolink:ChemicalSubstance 12-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_19138 CHEBI:58700 biolink:ChemicalSubstance 6-(alpha-D-glucosazaniumyl)-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_58700 chebi_ph7_3 UBERON:0005523 biolink:AnatomicalEntity rhombomere 7 the seventh transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order go-plus.json r7 http://purl.obolibrary.org/obo/UBERON_0005523 GO:0008919 biolink:MolecularActivity lipopolysaccharide glucosyltransferase I activity Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide. MetaCyc:2.4.1.58-RXN|EC:2.4.1.58 go-plus.json lipopolysaccharide glucosyltransferase activity|LPS glucosyltransferase I activity|UDPglucose:lipopolysaccharide glucosyltransferase activity|UDPglucose:lipopolysaccharide glucosyltransferase I|uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I|UDP-glucose:lipopolysaccharide glucosyltransferase activity|uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0008919 GO:0008918 biolink:MolecularActivity lipopolysaccharide 3-alpha-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide. MetaCyc:2.4.1.44-RXN|EC:2.4.1.44 go-plus.json lipopolysaccharide-alpha-1,3-D-galactosyltransferase|UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|LPS 3-alpha-galactosyltransferase activity|UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity|lipopolysaccharide galactosyltransferase activity|uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity|UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|UDP-galactose:polysaccharide galactosyltransferase activity|lipopolysaccharide 1,3-galactosyltransferase activity|uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0008918 GO:0008917 biolink:MolecularActivity lipopolysaccharide N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide. MetaCyc:2.4.1.56-RXN|EC:2.4.1.56 go-plus.json UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity|UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity|LPS N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0008917 GO:0018490 biolink:MolecularActivity 4-hydroxyphenylpyruvate oxidase activity Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2). KEGG_REACTION:R00042|MetaCyc:1.2.3.13-RXN|RHEA:17197|EC:1.2.3.13|UM-BBD_reactionID:r0299 go-plus.json 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0018490 GO:0018492 biolink:MolecularActivity carbon-monoxide dehydrogenase (acceptor) activity Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor. EC:1.2.7.4|RHEA:21040|MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN|UM-BBD_enzymeID:e0415 go-plus.json anaerobic carbon monoxide dehydrogenase activity|carbon monoxide dehydrogenase activity|carbon-monoxide:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018492 GO:0018491 biolink:MolecularActivity 2-oxobutyrate synthase activity Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin. UM-BBD_reactionID:r0358|MetaCyc:2-OXOBUTYRATE-SYNTHASE-RXN|RHEA:32135 go-plus.json 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)|2-ketobutyrate synthase activity|alpha-ketobutyrate-ferredoxin oxidoreductase activity|alpha-ketobutyrate synthase activity|2-oxobutyrate-ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018491 GO:0043454 biolink:BiologicalProcess alkyne catabolic process The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2. go-plus.json alkyne degradation|alkyne breakdown|alkyne catabolism http://purl.obolibrary.org/obo/GO_0043454 GO:0043453 biolink:BiologicalProcess alkyne biosynthetic process The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2. go-plus.json alkyne anabolism|alkyne synthesis|alkyne formation|alkyne biosynthesis http://purl.obolibrary.org/obo/GO_0043453 GO:0043456 biolink:BiologicalProcess regulation of pentose-phosphate shunt Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis. go-plus.json regulation of pentose phosphate shunt|regulation of pentose-phosphate pathway|regulation of pentose phosphate pathway http://purl.obolibrary.org/obo/GO_0043456 GO:0043455 biolink:BiologicalProcess regulation of secondary metabolic process Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. go-plus.json regulation of secondary metabolism http://purl.obolibrary.org/obo/GO_0043455 GO:0043450 biolink:BiologicalProcess alkene biosynthetic process The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. go-plus.json alkene anabolism|alkene synthesis|alkene biosynthesis|alkene formation http://purl.obolibrary.org/obo/GO_0043450 GO:0043452 biolink:BiologicalProcess cellular alkyne metabolic process The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells. go-plus.json alkyne metabolism http://purl.obolibrary.org/obo/GO_0043452 goslim_pir CHEBI:83697 biolink:ChemicalSubstance N(5)-alkyl-L-glutamine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83697 chebi_ph7_3 GO:0043451 biolink:BiologicalProcess alkene catabolic process The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. go-plus.json alkene catabolism|alkene degradation|alkene breakdown http://purl.obolibrary.org/obo/GO_0043451 CHEBI:138347 biolink:ChemicalSubstance triacylglycerol 54:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138347 chebi_ph7_3 GO:0043458 biolink:BiologicalProcess ethanol biosynthetic process involved in glucose fermentation to ethanol The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP. go-plus.json ethanol anabolism during fermentation|ethanol synthesis during fermentation|ethanol formation during fermentation http://purl.obolibrary.org/obo/GO_0043458 CHEBI:83690 biolink:ChemicalSubstance N-terminal N-acetyl-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83690 chebi_ph7_3 GO:0043457 biolink:BiologicalProcess regulation of cellular respiration Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds. go-plus.json http://purl.obolibrary.org/obo/GO_0043457 CL:0005019 biolink:Cell pancreatic epsilon cell Ghrelin secreting cells found in the exocrine pancreas. go-plus.json pancreatic E cell http://purl.obolibrary.org/obo/CL_0005019 CL:0005018 biolink:Cell ghrelin secreting cell A cell that secretes ghrelin, the peptide hormone that stimulates hunger. go-plus.json http://purl.obolibrary.org/obo/CL_0005018 GO:0043459 biolink:BiologicalProcess obsolete response to short exposure to lithium ion OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a single or short exposure to a lithium ion stimulus. go-plus.json response to short exposure to lithium ion http://purl.obolibrary.org/obo/GO_0043459 GO:0018487 biolink:MolecularActivity vanillate O-demethylase (anaerobic) activity Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate. UM-BBD_reactionID:r0758 go-plus.json http://purl.obolibrary.org/obo/GO_0018487 GO:0018486 biolink:MolecularActivity 2-butanone oxidase activity Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate. UM-BBD_reactionID:r0169 go-plus.json http://purl.obolibrary.org/obo/GO_0018486 CHEBI:138341 biolink:ChemicalSubstance (R)-2-alkyl-3-oxoalkanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138341 chebi_ph7_3 GO:0018489 biolink:MolecularActivity vanillate monooxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+). MetaCyc:RXN-2|MetaCyc:RXN-10891|EC:1.14.13.82|UM-BBD_reactionID:r0146|RHEA:13021|KEGG_REACTION:R05274 go-plus.json vanillate:oxygen oxidoreductase (demethylating)|vanillate demethylase (aerobic) activity|vanillate demethylase activity|4-hydroxy-3-methoxybenzoate demethylase activity http://purl.obolibrary.org/obo/GO_0018489 CHEBI:138340 biolink:ChemicalSubstance (2R,3S)-2-alkyl-3-hydroxyalkanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138340 chebi_ph7_3 GO:0018488 biolink:MolecularActivity aryl-aldehyde oxidase activity Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide. MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN|UM-BBD_reactionID:r0145|EC:1.2.3.9|RHEA:18569 go-plus.json aryl-aldehyde:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018488 GO:0018483 biolink:MolecularActivity 6-oxohexanoate dehydrogenase activity Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+. EC:1.2.1.63|MetaCyc:6-OXOHEXANOATE-OXIDATION-RXN|UM-BBD_reactionID:r0175|RHEA:13397 go-plus.json 6-oxohexanoate:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018483 CHEBI:138346 biolink:ChemicalSubstance triacylglycerol 54:9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138346 chebi_ph7_3 CL:0005012 biolink:Cell multi-ciliated epithelial cell A ciliated epithelial cell with many cilium. go-plus.json multiciliated epithelial cell|multiciliated cell|MCC|multi-ciliated cell http://purl.obolibrary.org/obo/CL_0005012 GO:0018482 biolink:MolecularActivity 4-formylbenzenesulfonate dehydrogenase activity Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH. EC:1.2.1.62|RHEA:18833|UM-BBD_reactionID:r0292|KEGG_REACTION:R05272|MetaCyc:1.2.1.62-RXN go-plus.json 4-formylbenzenesulfonate:NAD+ oxidoreductase activity|4-formylbenzenesulphonate dehydrogenase activity|toluene-sulfonate aldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018482 GO:0018485 biolink:MolecularActivity salicylaldehyde dehydrogenase activity Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+. UM-BBD_enzymeID:e0256|EC:1.2.1.65|RHEA:18537|MetaCyc:1.2.1.65-RXN go-plus.json salicylaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018485 GO:0018484 biolink:MolecularActivity 4-hydroxybenzaldehyde dehydrogenase activity Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+. RHEA:20305|EC:1.2.1.64|MetaCyc:HYDROXYBENZALDEHYDE-OXIDATION-NAD-RXN|UM-BBD_reactionID:r0273 go-plus.json p-hydroxybenzaldehyde dehydrogenase activity|3-hydroxybenzaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018484 GO:0043465 biolink:BiologicalProcess regulation of fermentation Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP). go-plus.json http://purl.obolibrary.org/obo/GO_0043465 GO:0043464 biolink:BiologicalProcess malolactic fermentation The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP. Wikipedia:Malolactic_fermentation go-plus.json malate fermentation|L-malate fermentation|malolactate fermentation|malo-lactate fermentation http://purl.obolibrary.org/obo/GO_0043464 GO:0043467 biolink:BiologicalProcess regulation of generation of precursor metabolites and energy Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. go-plus.json http://purl.obolibrary.org/obo/GO_0043467 GO:0043466 biolink:BiologicalProcess pyrimidine nucleobase fermentation The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP. go-plus.json pyrimidine base fermentation|pyrimidine fermentation http://purl.obolibrary.org/obo/GO_0043466 GO:0043461 biolink:BiologicalProcess proton-transporting ATP synthase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. go-plus.json F-type ATPase complex assembly http://purl.obolibrary.org/obo/GO_0043461 GO:0043460 biolink:BiologicalProcess obsolete response to long exposure to lithium ion OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a long or persistent exposure to a lithium ion stimulus. go-plus.json response to long exposure to lithium ion http://purl.obolibrary.org/obo/GO_0043460 GO:0043463 biolink:BiologicalProcess regulation of rhamnose catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose. go-plus.json regulation of rhamnose degradation|regulation of rhamnose breakdown|regulation of rhamnose catabolism http://purl.obolibrary.org/obo/GO_0043463 CHEBI:44089 biolink:ChemicalSubstance (2S)-2-methyltetradecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_44089 GO:0043462 biolink:BiologicalProcess regulation of ATPase activity Any process that modulates the rate of ATP hydrolysis by an ATPase. go-plus.json regulation of adenosinetriphosphatase activity http://purl.obolibrary.org/obo/GO_0043462 CHEBI:138359 biolink:ChemicalSubstance 4,4'-disulfanyldibutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138359 chebi_ph7_3 CL:0005026 biolink:Cell hepatoblast Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. go-plus.json http://purl.obolibrary.org/obo/CL_0005026 CHEBI:138358 biolink:ChemicalSubstance 4-sulfanylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138358 chebi_ph7_3 GO:0043469 biolink:BiologicalProcess regulation of D-xylose catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose. go-plus.json http://purl.obolibrary.org/obo/GO_0043469 GO:0043468 biolink:BiologicalProcess regulation of fucose catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose. go-plus.json http://purl.obolibrary.org/obo/GO_0043468 GO:0018498 biolink:MolecularActivity 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate. UM-BBD_enzymeID:e0308|RHEA:25062|MetaCyc:PHENPRODIOLDEHYDROG-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0018498 CL:0005020 biolink:Cell lymphangioblast Lymphatic progenitor cells. go-plus.json http://purl.obolibrary.org/obo/CL_0005020 GO:0018497 biolink:MolecularActivity 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS. UM-BBD_reactionID:r0514 go-plus.json DDMS dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018497 GO:0018499 biolink:MolecularActivity cis-2,3-dihydrodiol DDT dehydrogenase activity Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT. UM-BBD_reactionID:r0451 go-plus.json http://purl.obolibrary.org/obo/GO_0018499 CL:0005024 biolink:Cell somatomotor neuron A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. go-plus.json somatic motor neuron http://purl.obolibrary.org/obo/CL_0005024 GO:0018494 biolink:MolecularActivity carvone reductase activity Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone. EC:1.3.99.25|MetaCyc:RXN-9419|MetaCyc:RXN-9403|UM-BBD_reactionID:r0732 go-plus.json http://purl.obolibrary.org/obo/GO_0018494 GO:0018493 biolink:MolecularActivity formylmethanofuran dehydrogenase activity Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran. KEGG_REACTION:R03015|RHEA:19841|MetaCyc:FORMYLMETHANOFURAN-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0345|EC:1.2.7.12 go-plus.json formylmethanofuran:(acceptor) oxidoreductase activity|formylmethanofuran:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018493 CL:0005022 biolink:Cell vascular lymphangioblast Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. go-plus.json parachordal lymphangioblast http://purl.obolibrary.org/obo/CL_0005022 GO:0018496 biolink:MolecularActivity 2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA. UM-BBD_reactionID:r0205 go-plus.json http://purl.obolibrary.org/obo/GO_0018496 GO:0018495 biolink:MolecularActivity 2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA. UM-BBD_reactionID:r0192 go-plus.json http://purl.obolibrary.org/obo/GO_0018495 CHEBI:44075 biolink:ChemicalSubstance methyl L-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44075 GO:0043470 biolink:BiologicalProcess regulation of carbohydrate catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. go-plus.json http://purl.obolibrary.org/obo/GO_0043470 GO:0018470 biolink:MolecularActivity 4-hydroxybutaraldehyde dehydrogenase activity Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate. UM-BBD_reactionID:r0014 go-plus.json http://purl.obolibrary.org/obo/GO_0018470 CHEBI:44074 biolink:ChemicalSubstance molybdopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_44074 GO:0043476 biolink:BiologicalProcess pigment accumulation The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus. go-plus.json pigment accumulation in response to external stimulus http://purl.obolibrary.org/obo/GO_0043476 GO:0043475 biolink:BiologicalProcess pigment metabolic process involved in pigment accumulation The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment. go-plus.json pigment metabolism during pigment accumulation|pigment metabolic process during pigment accumulation http://purl.obolibrary.org/obo/GO_0043475 GO:0043478 biolink:BiologicalProcess pigment accumulation in response to UV light The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0043478 GO:0043477 biolink:BiologicalProcess pigment biosynthetic process involved in pigment accumulation The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation. go-plus.json pigment biosynthetic process during pigment accumulation http://purl.obolibrary.org/obo/GO_0043477 GO:0043472 biolink:MolecularActivity IgD binding Binding to an immunoglobulin of a D isotype. go-plus.json http://purl.obolibrary.org/obo/GO_0043472 GO:0043471 biolink:BiologicalProcess regulation of cellular carbohydrate catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells. go-plus.json http://purl.obolibrary.org/obo/GO_0043471 GO:0043474 biolink:BiologicalProcess pigment metabolic process involved in pigmentation The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell. go-plus.json pigment metabolism during pigmentation|pigment metabolic process during pigmentation http://purl.obolibrary.org/obo/GO_0043474 GO:0043473 biolink:BiologicalProcess pigmentation The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0043473 goslim_chembl|goslim_pir|goslim_generic CHEBI:138328 biolink:ChemicalSubstance L-firefly luciferyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138328 chebi_ph7_3 CHEBI:138327 biolink:ChemicalSubstance hydroperoxy(hydroxy)icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138327 CHEBI:138326 biolink:ChemicalSubstance (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138326 CHEBI:138325 biolink:ChemicalSubstance (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138325 GO:0018469 biolink:MolecularActivity myrtenal dehydrogenase activity Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid. UM-BBD_reactionID:r0711 go-plus.json http://purl.obolibrary.org/obo/GO_0018469 GO:0043479 biolink:BiologicalProcess pigment accumulation in tissues in response to UV light The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0043479 GO:0018468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018468 CHEBI:138329 biolink:ChemicalSubstance ent-Photinus luciferin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138329 chebi_ph7_3 GO:0018465 biolink:MolecularActivity vanillyl-alcohol oxidase activity Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin. EC:1.1.3.38|KEGG_REACTION:R02877|UM-BBD_reactionID:r0651|RHEA:10036|MetaCyc:1.1.3.38-RXN go-plus.json 4-hydroxy-2-methoxybenzyl alcohol oxidase activity|vanillyl alcohol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018465 CHEBI:138320 biolink:ChemicalSubstance monoalkyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138320 GO:0018464 biolink:MolecularActivity 3-hydroxypimeloyl-CoA dehydrogenase activity Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH. KEGG_REACTION:R05305|RHEA:11168|UM-BBD_reactionID:r0196|MetaCyc:1.1.1.259-RXN|EC:1.1.1.259 go-plus.json 3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018464 GO:0018467 biolink:MolecularActivity formaldehyde dehydrogenase activity Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH. MetaCyc:FORMALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.46|KEGG_REACTION:R00604|UM-BBD_reactionID:r0240|RHEA:16425 go-plus.json glutathione-independent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018467 GO:0018466 biolink:MolecularActivity limonene-1,2-diol dehydrogenase activity Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene. EC:1.1.99.-|UM-BBD_reactionID:r0735 go-plus.json http://purl.obolibrary.org/obo/GO_0018466 GO:0018461 biolink:MolecularActivity fluoren-9-ol dehydrogenase activity Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+. EC:1.1.1.256|UM-BBD_reactionID:r0408|MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN go-plus.json 9-fluorenol dehydrogenase activity|fluoren-9-ol:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018461 GO:0018460 biolink:MolecularActivity cyclohexanol dehydrogenase activity Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+. UM-BBD_reactionID:r0165|RHEA:10044|MetaCyc:CYCLOHEXANOL-DEHYDROGENASE-RXN|EC:1.1.1.245 go-plus.json cyclohexanol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018460 GO:0018463 biolink:MolecularActivity 6-hydroxyhexanoate dehydrogenase activity Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH. UM-BBD_reactionID:r0174|RHEA:14225|MetaCyc:6-HYDROXYHEXANOATE-OXIDATION-RXN|EC:1.1.1.258|KEGG_REACTION:R05283 go-plus.json 6-hydroxyhexanoate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018463 GO:0018462 biolink:MolecularActivity 4-(hydroxymethyl)benzenesulfonate dehydrogenase activity Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH. RHEA:24412|MetaCyc:1.1.1.257-RXN|UM-BBD_reactionID:r0291|EC:1.1.1.257|KEGG_REACTION:R05271 go-plus.json 4-sulfobenzyl alcohol dehydrogenase activity|4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity|4-(hydroxymethyl)benzenesulphonate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018462 CHEBI:138321 biolink:ChemicalSubstance O-[S-(4-hydroxybenzoyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138321 chebi_ph7_3 GO:0018481 biolink:MolecularActivity 4-hydroxymuconic-semialdehyde dehydrogenase activity Catalysis of the reaction: cis,trans-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH. UM-BBD_reactionID:r0229|EC:1.2.1.61|RHEA:22420|KEGG_REACTION:R05236|MetaCyc:1.2.1.61-RXN go-plus.json 4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018481 GO:0043481 biolink:BiologicalProcess anthocyanin accumulation in tissues in response to UV light The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0043481 GO:0043480 biolink:BiologicalProcess pigment accumulation in tissues The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus. go-plus.json organismal pigment accumulation http://purl.obolibrary.org/obo/GO_0043480 GO:0018480 biolink:MolecularActivity 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+. UM-BBD_reactionID:r0365|EC:1.2.1.60|RHEA:15681|MetaCyc:CHMS-DEHYDROGENASE-RXN go-plus.json 5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity|carboxymethylhydroxymuconic semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018480 PR:000020795 biolink:Protein neurotrophin-3 proteolytic cleavage product A neurotrophin-3 that has been processed by proteolytic cleavage. go-plus.json NTF3/ClvPrd http://purl.obolibrary.org/obo/PR_000020795 GO:0043487 biolink:BiologicalProcess regulation of RNA stability Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0043487 GO:0043486 biolink:BiologicalProcess histone exchange The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. go-plus.json histone replacement|histone chaperone http://purl.obolibrary.org/obo/GO_0043486 GO:0043489 biolink:BiologicalProcess RNA stabilization Prevention of degradation of RNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0043489 GO:0043488 biolink:BiologicalProcess regulation of mRNA stability Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0043488 GO:0043483 biolink:BiologicalProcess anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus. go-plus.json anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light|anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus|anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus http://purl.obolibrary.org/obo/GO_0043483 GO:0043482 biolink:BiologicalProcess cellular pigment accumulation The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0043482 GO:0043485 biolink:BiologicalProcess endosome to pigment granule transport The directed movement of substances from endosomes to pigment granules. go-plus.json http://purl.obolibrary.org/obo/GO_0043485 GO:0043484 biolink:BiologicalProcess regulation of RNA splicing Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0043484 CL:0005006 biolink:Cell ionocyte Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. go-plus.json http://purl.obolibrary.org/obo/CL_0005006 CHEBI:138339 biolink:ChemicalSubstance 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-icosatetraenoyl]-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138339 CL:0005005 biolink:Cell cyanoblast A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore. go-plus.json http://purl.obolibrary.org/obo/CL_0005005 CL:0005004 biolink:Cell pigment erythroblast A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore. go-plus.json http://purl.obolibrary.org/obo/CL_0005004 CL:0005003 biolink:Cell leucoblast A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore. go-plus.json http://purl.obolibrary.org/obo/CL_0005003 GO:0018479 biolink:MolecularActivity benzaldehyde dehydrogenase (NAD+) activity Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+. UM-BBD_reactionID:r0269|RHEA:11840|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|EC:1.2.1.28 go-plus.json benzaldehyde (NAD) dehydrogenase activity|benzaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018479 CHEBI:138331 biolink:ChemicalSubstance cholesteryl icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138331 chebi_ph7_3 GO:0018476 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018476 OBO:GOCHE_60311 biolink:OntologyClass substance with thyroid hormone role go-plus.json http://purl.obolibrary.org/obo/GOCHE_60311 3_STAR CHEBI:138330 biolink:ChemicalSubstance pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138330 chebi_ph7_3 GO:0018475 biolink:MolecularActivity trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid. UM-BBD_reactionID:r0745 go-plus.json http://purl.obolibrary.org/obo/GO_0018475 GO:0018478 biolink:MolecularActivity malonate-semialdehyde dehydrogenase (acetylating) activity Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+. RHEA:22988|MetaCyc:1.2.1.18-RXN|EC:1.2.1.18 go-plus.json malonic semialdehyde oxidative decarboxylase activity|3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating) http://purl.obolibrary.org/obo/GO_0018478 GO:0018477 biolink:MolecularActivity benzaldehyde dehydrogenase (NADP+) activity Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+. RHEA:21660|EC:1.2.1.7|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN|UM-BBD_enzymeID:e0079 go-plus.json NADP-linked benzaldehyde dehydrogenase|benzaldehyde:NADP+ oxidoreductase http://purl.obolibrary.org/obo/GO_0018477 GO:0018472 biolink:MolecularActivity 1-hydroxy-2-naphthaldehyde dehydrogenase activity Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate. UM-BBD_reactionID:r0485 go-plus.json http://purl.obolibrary.org/obo/GO_0018472 CL:0005002 biolink:Cell xanthoblast A non-terminally differentiated cell that differentiates into a xanthophore. go-plus.json http://purl.obolibrary.org/obo/CL_0005002 CL:0005001 biolink:Cell iridoblast A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore. go-plus.json http://purl.obolibrary.org/obo/CL_0005001 CHEBI:138334 biolink:ChemicalSubstance N(tele)-(N(7)-methylguanosine 5'-phosphonato)-L-histidine zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138334 chebi_ph7_3 GO:0018471 biolink:MolecularActivity 4-chlorobenzaldehyde oxidase activity Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-. EC:1.14.13.-|UM-BBD_reactionID:r0447 go-plus.json http://purl.obolibrary.org/obo/GO_0018471 CL:0005000 biolink:Cell spinal cord interneuron A CNS interneuron located in the spinal cord. go-plus.json http://purl.obolibrary.org/obo/CL_0005000 GO:0018474 biolink:MolecularActivity 2-carboxybenzaldehyde dehydrogenase activity Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate. UM-BBD_reactionID:r0490|EC:1.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018474 CHEBI:138332 biolink:ChemicalSubstance 11(S)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_138332 GO:0018473 biolink:MolecularActivity cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid. UM-BBD_reactionID:r0744 go-plus.json http://purl.obolibrary.org/obo/GO_0018473 GO:0043490 biolink:BiologicalProcess malate-aspartate shuttle The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle. Wikipedia:Malate-aspartate_shuttle go-plus.json malate:aspartate shuttle|malate aspartate shuttle|malate/aspartate shuttle http://purl.obolibrary.org/obo/GO_0043490 CHEBI:19098 biolink:ChemicalSubstance 1-pyrrolinecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19098 GO:0043492 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043492 GO:0043491 biolink:BiologicalProcess protein kinase B signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound. go-plus.json PKB signaling cascade|protein kinase B signal transduction|protein kinase B signalling cascade|AKT signalling cascade|PKB signalling cascade|protein kinase B signaling cascade|AKT signaling|PKB signaling|AKT signal transduction|PKB signal transduction|AKT signaling cascade http://purl.obolibrary.org/obo/GO_0043491 CHEBI:19092 biolink:ChemicalSubstance 1-pyrroline go-plus.json http://purl.obolibrary.org/obo/CHEBI_19092 GO:0043498 biolink:MolecularActivity obsolete cell surface binding OBSOLETE. Binding to a component on the surface of a cell. go-plus.json cell surface binding http://purl.obolibrary.org/obo/GO_0043498 GO:0043497 biolink:BiologicalProcess regulation of protein heterodimerization activity Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer. go-plus.json http://purl.obolibrary.org/obo/GO_0043497 CHEBI:20081 biolink:ChemicalSubstance 3-hydroxypropionyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_20081 GO:0043499 biolink:MolecularActivity obsolete eukaryotic cell surface binding OBSOLETE. Binding to a component on the surface of a eukaryotic cell. go-plus.json eukaryotic cell surface binding http://purl.obolibrary.org/obo/GO_0043499 GO:0043494 biolink:CellularComponent CLRC complex An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi. go-plus.json CLRC ubiquitin ligase complex|Rik1-E3 ubiquitin ligase complex|Rik1 E3 ubiquitin ligase complex|Clr4-Rik1-Cul4 complex http://purl.obolibrary.org/obo/GO_0043494 GO:0043493 biolink:CellularComponent viral terminase complex A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides. go-plus.json virus terminase complex|phage terminase complex http://purl.obolibrary.org/obo/GO_0043493 GO:0043496 biolink:BiologicalProcess regulation of protein homodimerization activity Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. go-plus.json http://purl.obolibrary.org/obo/GO_0043496 GO:0043495 biolink:MolecularActivity protein-membrane adaptor activity The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. go-plus.json anchoring|protein membrane anchor|protein membrane adaptor activity|protein membrane adaptor http://purl.obolibrary.org/obo/GO_0043495 CHEBI:138306 biolink:ChemicalSubstance aromatic (S)-hydroxynitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_138306 chebi_ph7_3 CHEBI:58695 biolink:ChemicalSubstance D-tagatofuranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58695 chebi_ph7_3 CHEBI:58694 biolink:ChemicalSubstance D-tagatofuranose 1,6-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58694 chebi_ph7_3 CHEBI:138305 biolink:ChemicalSubstance (21S)-21,22-epoxypolypoda-8(26)-13,17-trien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138305 chebi_ph7_3 CHEBI:58693 biolink:ChemicalSubstance (7R)-7-(4-carboxylatobutanamido)cephalosporanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58693 chebi_ph7_3 CHEBI:138303 biolink:ChemicalSubstance alpha-onocerin go-plus.json http://purl.obolibrary.org/obo/CHEBI_138303 chebi_ph7_3 CHEBI:58692 biolink:ChemicalSubstance (R)-2-benzylsuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58692 chebi_ph7_3 GO:0018447 biolink:MolecularActivity chloral hydrate dehydrogenase activity Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol. UM-BBD_enzymeID:e0229 go-plus.json http://purl.obolibrary.org/obo/GO_0018447 CHEBI:58691 biolink:ChemicalSubstance (3R,4S,5R)-3,4,5-trihydroxy-6-oxocyclohex-1-en-1-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58691 CHEBI:138309 biolink:ChemicalSubstance C-terminal L-alpha-amino-acid-L-tyrosinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138309 chebi_ph7_3 GO:0018446 biolink:MolecularActivity pinocarveol dehydrogenase activity Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-. UM-BBD_reactionID:r0717 go-plus.json http://purl.obolibrary.org/obo/GO_0018446 CHEBI:58690 biolink:ChemicalSubstance 1,6-anhydro-N-acetyl-beta-muramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58690 chebi_ph7_3 GO:0018449 biolink:MolecularActivity 1-phenylethanol dehydrogenase activity Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2. UM-BBD_reactionID:r0032 go-plus.json http://purl.obolibrary.org/obo/GO_0018449 CHEBI:138307 biolink:ChemicalSubstance (3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138307 chebi_ph7_3 GO:0018448 biolink:MolecularActivity hydroxymethylmethylsilanediol oxidase activity Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O. UM-BBD_reactionID:r0638 go-plus.json http://purl.obolibrary.org/obo/GO_0018448 GO:0018443 biolink:BiologicalProcess obsolete enzyme active site formation via L-aspartic 4-phosphoric anhydride OBSOLETE. The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride. RESID:AA0033 go-plus.json http://purl.obolibrary.org/obo/GO_0018443 GO:0018442 biolink:BiologicalProcess peptidyl-glutamic acid esterification The addition of an ester group to a glutamic acid residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018442 GO:0018445 biolink:MolecularActivity prothoracicotrophic hormone activity The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects. go-plus.json http://purl.obolibrary.org/obo/GO_0018445 GO:0018444 biolink:CellularComponent translation release factor complex A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome. go-plus.json peptide chain release factor|eukaryotic peptide chain release factor http://purl.obolibrary.org/obo/GO_0018444 CHEBI:138302 biolink:ChemicalSubstance (12E)-labda-8(17),12,14-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138302 chebi_ph7_3 CHEBI:58699 biolink:ChemicalSubstance L-methioninium (S)-S-oxide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_58699 chebi_ph7_3 CHEBI:138301 biolink:ChemicalSubstance labda-7,13(16),14-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138301 chebi_ph7_3 CHEBI:58698 biolink:ChemicalSubstance molybdopterin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58698 chebi_ph7_3 GO:0018441 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase. RESID:AA0300 go-plus.json iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulphide http://purl.obolibrary.org/obo/GO_0018441 CHEBI:58697 biolink:ChemicalSubstance (2R,4S)-2,4-diazaniumylpentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58697 chebi_ph7_3 CHEBI:138300 biolink:ChemicalSubstance 2-hydroxytetradecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138300 chebi_ph7_3 GO:0018440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018440 CHEBI:58696 biolink:ChemicalSubstance flaviolin-2-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58696 chebi_ph7_3 CHEBI:58684 biolink:ChemicalSubstance 3-epi-3-hydroxy-2'-deoxymugineate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58684 chebi_ph7_3 CHEBI:138317 biolink:ChemicalSubstance N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138317 chebi_ph7_3 CHEBI:58683 biolink:ChemicalSubstance 3-sulfonatolactate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58683 chebi_ph7_3 CHEBI:138316 biolink:ChemicalSubstance N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138316 chebi_ph7_3 CHEBI:58682 biolink:ChemicalSubstance 6-hydroxypseudooxynicotinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58682 chebi_ph7_3 CHEBI:138315 biolink:ChemicalSubstance N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138315 chebi_ph7_3 CHEBI:138314 biolink:ChemicalSubstance S-allylsulfenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138314 chebi_ph7_3 CHEBI:58681 biolink:ChemicalSubstance 5-phospho-beta-D-ribosylaminium(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58681 chebi_ph7_3 GO:0018458 biolink:MolecularActivity isopiperitenol dehydrogenase activity Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH. UM-BBD_reactionID:r0740|RHEA:20860|KEGG_REACTION:R03261|MetaCyc:ISOPIPERITENOL-DEHYDROGENASE-RXN|EC:1.1.1.223 go-plus.json (-)-trans-isopiperitenol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018458 CHEBI:58680 biolink:ChemicalSubstance O-phosphonatooxy-D-serine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58680 chebi_ph7_3 GO:0018457 biolink:MolecularActivity perillyl-alcohol dehydrogenase activity Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde. MetaCyc:PERILLYL-ALCOHOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03945|RHEA:10664|EC:1.1.1.144|UM-BBD_reactionID:r0729 go-plus.json perillyl-alcohol:NAD+ oxidoreductase activity|perillyl alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018457 CHEBI:138319 biolink:ChemicalSubstance monoalk-1-enyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138319 GO:0018459 biolink:MolecularActivity carveol dehydrogenase activity Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH. RHEA:13629|MetaCyc:CARVEOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03114|EC:1.1.1.243|UM-BBD_reactionID:r0714 go-plus.json (-)-trans-carveol:NADP+ oxidoreductase activity|(-)-trans-carveol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018459 CHEBI:138318 biolink:ChemicalSubstance N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138318 chebi_ph7_3 GO:0018454 biolink:MolecularActivity acetoacetyl-CoA reductase activity Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+. UM-BBD_reactionID:r0202|RHEA:22256|EC:1.1.1.36|MetaCyc:RXN-7698 go-plus.json NADPH:acetoacetyl-CoA reductase activity|(R)-3-hydroxyacyl-CoA dehydrogenase activity|(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity|NADP-linked acetoacetyl CoA reductase activity|short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity|D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity|beta-ketoacyl-CoA reductase|acetoacetyl coenzyme A reductase activity|D-3-hydroxyacyl-CoA reductase activity|hydroxyacyl coenzyme-A dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018454 GO:0018453 biolink:MolecularActivity 2-hydroxytetrahydrofuran dehydrogenase activity Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone. UM-BBD_reactionID:r0018 go-plus.json http://purl.obolibrary.org/obo/GO_0018453 GO:0018456 biolink:MolecularActivity aryl-alcohol dehydrogenase (NAD+) activity Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+. EC:1.1.1.90|RHEA:12076|UM-BBD_enzymeID:e0019|MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN go-plus.json benzyl alcohol dehydrogenase activity|aryl-alcohol:NAD+ oxidoreductase activity|p-hydroxybenzyl alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018456 GO:0018455 biolink:MolecularActivity alcohol dehydrogenase [NAD(P)+] activity Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+. RHEA:10736|EC:1.1.1.71|UM-BBD_reactionID:r0172|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN go-plus.json alcohol:NAD(P)+ oxidoreductase activity|aldehyde reductase (NADPH/NADH) http://purl.obolibrary.org/obo/GO_0018455 CHEBI:58689 biolink:ChemicalSubstance (1R,6R)-2-(3-carboxylatopropanoyl)-6-hydroxycyclohexa-2,4-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58689 chebi_ph7_3 GO:0018450 biolink:MolecularActivity myrtenol dehydrogenase activity Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal. UM-BBD_reactionID:r0710 go-plus.json http://purl.obolibrary.org/obo/GO_0018450 CHEBI:138313 biolink:ChemicalSubstance (+)-kolavelool go-plus.json http://purl.obolibrary.org/obo/CHEBI_138313 chebi_ph7_3 CHEBI:58688 biolink:ChemicalSubstance divinyl chlorophyllide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58688 CHEBI:58687 biolink:ChemicalSubstance pheophorbide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58687 chebi_ph7_3 GO:0018452 biolink:MolecularActivity 5-exo-hydroxycamphor dehydrogenase activity Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane. MetaCyc:R542-RXN|EC:1.1.1.327|UM-BBD_reactionID:r0427|RHEA:32879 go-plus.json http://purl.obolibrary.org/obo/GO_0018452 CHEBI:138311 biolink:ChemicalSubstance (+)-kolavenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138311 chebi_ph7_3 CHEBI:58686 biolink:ChemicalSubstance chlorophyllide b(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58686 GO:0018451 biolink:MolecularActivity epoxide dehydrogenase activity Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA. UM-BBD_reactionID:r0595 go-plus.json http://purl.obolibrary.org/obo/GO_0018451 CHEBI:58685 biolink:ChemicalSubstance 3''-deamino-3''-oxonicotianaminium(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58685 chebi_ph7_3 CHEBI:138310 biolink:ChemicalSubstance (-)-kolavenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138310 chebi_ph7_3 CHEBI:20067 biolink:ChemicalSubstance 3-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20067 CHEBI:20060 biolink:ChemicalSubstance 3-hydroxy fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_20060 PR:000029189 biolink:Protein AKT kinase A protein that has a core domain composition consisting of a PH domain (Pfam:PF00169), Protein kinase domain (Pfam:PF00069) and a Protein kinase C terminal domain (Pfam:PF00433). Mammals have three genes encoding AKT1, AKT2 and AKT3. The second messenger phosphatidylinositol-3,4,5-trisphosphate [PIP(3)], product of phosphatidylinositol 3-kinase, acts largely through its role as a kinase activator. Binding of the pleckstrin domain to PIP(3) results in its targeting to the plasma membrane. Full activity is gained only after phosphorylation at two sites. go-plus.json AKT|serine-threonine kinase Akt|PKB http://purl.obolibrary.org/obo/PR_000029189 CHEBI:58673 biolink:ChemicalSubstance ADP-D-ribose 2'-phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58673 chebi_ph7_3 GO:0018429 biolink:BiologicalProcess copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide. RESID:AA0298 go-plus.json copper incorporation into copper-sulphur cluster via heptakis-L-histidino tetracopper mu4-sulphide hydroxide http://purl.obolibrary.org/obo/GO_0018429 GO:0018428 biolink:BiologicalProcess copper incorporation into copper-sulfur cluster The incorporation of copper into a copper-sulfur cluster. go-plus.json copper incorporation into copper-sulphur cluster http://purl.obolibrary.org/obo/GO_0018428 CHEBI:58672 biolink:ChemicalSubstance L-2-aminoadipate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58672 chebi_ph7_3 CHEBI:58671 biolink:ChemicalSubstance L-3-oxoalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58671 CHEBI:58670 biolink:ChemicalSubstance 4-oxoprolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58670 GO:0018425 biolink:BiologicalProcess O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds. RESID:AA0296 go-plus.json O3-(N-acetylglucosamine-1-phosphoryl)-L-serine anabolism|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine synthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine formation http://purl.obolibrary.org/obo/GO_0018425 GO:0018424 biolink:BiologicalProcess peptidyl-glutamic acid poly-ADP-ribosylation This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way. RESID:AA0295 go-plus.json http://purl.obolibrary.org/obo/GO_0018424 GO:0018427 biolink:BiologicalProcess copper incorporation into metallo-sulfur cluster The incorporation of copper into a metallo-sulfur cluster. go-plus.json copper incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0018427 GO:0018426 biolink:BiologicalProcess O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage. RESID:AA0297 go-plus.json O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine anabolism|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine synthesis|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine formation|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthesis http://purl.obolibrary.org/obo/GO_0018426 GO:0018421 biolink:MolecularActivity UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018421 GO:0018420 biolink:BiologicalProcess peptide cross-linking via N6-(L-isoaspartyl)-L-lysine The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues. RESID:AA0294 go-plus.json http://purl.obolibrary.org/obo/GO_0018420 CHEBI:58679 biolink:ChemicalSubstance 17-O-acetylajmalinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58679 chebi_ph7_3 GO:0018423 biolink:MolecularActivity protein C-terminal leucine carboxyl O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein. Reactome:R-HSA-8856945 go-plus.json protein phosphatase methyltransferase activity|protein-leucine O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0018423 GO:0018422 biolink:MolecularActivity GDP-mannose:serine-protein mannose-1-phosphotransferase activity Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018422 CHEBI:58678 biolink:ChemicalSubstance luteolin 7-O-[(beta-D-glucosyluronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58678 CHEBI:58677 biolink:ChemicalSubstance (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58677 chebi_ph7_3 CHEBI:58675 biolink:ChemicalSubstance O-phosphonato-L-threonine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58675 chebi_ph7_3 CHEBI:58674 biolink:ChemicalSubstance D-fructofuranose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58674 chebi_ph7_3 CHEBI:20070 biolink:ChemicalSubstance 3-hydroxyhexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20070 chebi_ph7_3 CHEBI:44027 biolink:ChemicalSubstance menaquinone-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_44027 chebi_ph7_3 GO:0018439 biolink:BiologicalProcess peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester. RESID:AA0299 go-plus.json peptidyl-leucine esterification http://purl.obolibrary.org/obo/GO_0018439 CHEBI:58661 biolink:ChemicalSubstance trypanothione disulfide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58661 chebi_ph7_3 CHEBI:58660 biolink:ChemicalSubstance CDP-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58660 chebi_ph7_3 CHEBI:58669 biolink:ChemicalSubstance but-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58669 chebi_ph7_3 CHEBI:58668 biolink:ChemicalSubstance (3S)-citramalyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58668 chebi_ph7_3 CHEBI:58667 biolink:ChemicalSubstance (R)-1-pyrroline-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58667 chebi_ph7_3 CHEBI:58665 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58665 chebi_ph7_3 OBO:GOCHE_50906 biolink:OntologyClass substance with role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50906 3_STAR GO:0102111 biolink:MolecularActivity gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide. MetaCyc:RXN-113 go-plus.json http://purl.obolibrary.org/obo/GO_0102111 GO:0102113 biolink:MolecularActivity hypoxia-inducible factor-asparagine oxygenase activity Catalysis of the reaction: 2-oxoglutarate + O2 + a hypoxia inducible factor (HIF) alpha subunit = succinate + carbon dioxide + a (3S)-3-hydroxy-L-asparagine-HIF alpha subunit. EC:1.14.11.30|RHEA:54268|MetaCyc:RXN-11321 go-plus.json http://purl.obolibrary.org/obo/GO_0102113 GO:0102115 biolink:MolecularActivity peptidoglycan asparagine synthase activity Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid. MetaCyc:RXN-11338 go-plus.json http://purl.obolibrary.org/obo/GO_0102115 GO:0102114 biolink:MolecularActivity caprate dehydroxylase activity Catalysis of the reaction: decanoate + NADPH + O2 + H+ <=> 10-hydroxycaprate + NADP + H2O. MetaCyc:RXN-11325 go-plus.json http://purl.obolibrary.org/obo/GO_0102114 GO:0102117 biolink:MolecularActivity gibberellin A9 carboxyl methyltransferase activity Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine. RHEA:36119|MetaCyc:RXN-11358|EC:2.1.1.275 go-plus.json http://purl.obolibrary.org/obo/GO_0102117 PR:000005110 biolink:Protein cholecystokinin A protein that is a translation product of the human CCK gene or a 1:1 ortholog thereof. go-plus.json CCK http://purl.obolibrary.org/obo/PR_000005110 GO:0102116 biolink:MolecularActivity laurate hydroxylase activity Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O. MetaCyc:RXN-11340 go-plus.json http://purl.obolibrary.org/obo/GO_0102116 GO:0102119 biolink:MolecularActivity gibberellin A20 carboxyl methyltransferase activity Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine. MetaCyc:RXN-11360 go-plus.json http://purl.obolibrary.org/obo/GO_0102119 GO:0102118 biolink:MolecularActivity gibberellin A4 carboxyl methyltransferase activity Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine. RHEA:36107|MetaCyc:RXN-11359|EC:2.1.1.276 go-plus.json http://purl.obolibrary.org/obo/GO_0102118 GO:0102122 biolink:MolecularActivity gibberellin A34 carboxyl methyltransferase activity Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine. MetaCyc:RXN-11384|RHEA:36127 go-plus.json http://purl.obolibrary.org/obo/GO_0102122 CHEBI:83628 biolink:ChemicalSubstance N-acylammonia go-plus.json http://purl.obolibrary.org/obo/CHEBI_83628 chebi_ph7_3 GO:0102121 biolink:MolecularActivity ceramidase activity Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid. MetaCyc:RXN-11375|EC:3.5.1.23 go-plus.json http://purl.obolibrary.org/obo/GO_0102121 CHEBI:83627 biolink:ChemicalSubstance hexadecanoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83627 chebi_ph7_3 GO:0102124 biolink:MolecularActivity gibberellin A12 16alpha,17 epoxidase activity Catalysis of the reaction: gibberellin A12 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A12 + H2O + NAD(P). MetaCyc:RXN-11387 go-plus.json http://purl.obolibrary.org/obo/GO_0102124 CHEBI:83626 biolink:ChemicalSubstance tetradecanoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83626 chebi_ph7_3 GO:0102123 biolink:MolecularActivity gibberellin A4 16alpha,17 epoxidase activity Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P). MetaCyc:RXN-11385 go-plus.json http://purl.obolibrary.org/obo/GO_0102123 CHEBI:83625 biolink:ChemicalSubstance O-adenyl-L-tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83625 GO:0102126 biolink:MolecularActivity coniferyl aldehyde 5-hydroxylase activity Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O. MetaCyc:RXN-1142 go-plus.json http://purl.obolibrary.org/obo/GO_0102126 CHEBI:83624 biolink:ChemicalSubstance O-adenyl-L-tyrosine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83624 chebi_ph7_3 GO:0102125 biolink:MolecularActivity gibberellin A9 16alpha,17 epoxidase activity Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P). MetaCyc:RXN-11388 go-plus.json http://purl.obolibrary.org/obo/GO_0102125 CHEBI:83623 biolink:ChemicalSubstance dodecanoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83623 chebi_ph7_3 GO:0102128 biolink:MolecularActivity chalcone synthase activity Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide. MetaCyc:RXN-11468|EC:2.3.1.74 go-plus.json http://purl.obolibrary.org/obo/GO_0102128 CHEBI:83622 biolink:ChemicalSubstance fatty acyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83622 chebi_ph7_3 GO:0102127 biolink:MolecularActivity 8-oxoguanine deaminase activity Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O <=> 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium. EC:3.5.4.32|MetaCyc:RXN-11455|RHEA:32067 go-plus.json http://purl.obolibrary.org/obo/GO_0102127 CHEBI:83621 biolink:ChemicalSubstance fatty acyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_83621 PR:000020737 biolink:Protein beta-nerve growth factor proteolytic cleavage product A beta-nerve growth factor that has been processed by proteolytic cleavage. go-plus.json NGF/ClvPrd http://purl.obolibrary.org/obo/PR_000020737 PR:000019751 biolink:Protein pro-epidermal growth factor proteolytic cleavage product A pro-epidermal growth factor that has been processed by proteolytic cleavage. go-plus.json EGF/ClvPrd http://purl.obolibrary.org/obo/PR_000019751 PR:000020722 biolink:Protein NEDD8 protein proteolytic cleavage product A NEDD8 protein that has been processed by proteolytic cleavage. go-plus.json NEDD8/ClvPrd http://purl.obolibrary.org/obo/PR_000020722 GO:0102131 biolink:MolecularActivity obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxyglutaryl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-glutaryl-[acp] methyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0102131 GO:0102130 biolink:MolecularActivity malonyl-CoA methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a malonyl-[acp] = S-adenosyl-L-homocysteine + a malonyl-[acp] methyl ester. RHEA:17105|EC:2.1.1.197|MetaCyc:RXN-11475 go-plus.json http://purl.obolibrary.org/obo/GO_0102130 GO:0102133 biolink:MolecularActivity limonene hydroxylase activity Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O. MetaCyc:RXN-11493 go-plus.json http://purl.obolibrary.org/obo/GO_0102133 GO:0102132 biolink:MolecularActivity obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester. go-plus.json http://purl.obolibrary.org/obo/GO_0102132 GO:0102135 biolink:MolecularActivity (22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O. MetaCyc:RXN-11530 go-plus.json http://purl.obolibrary.org/obo/GO_0102135 OBO:cl#has_completed biolink:OntologyClass has_completed has_completed go-plus.json http://purl.obolibrary.org/obo/cl#has_completed GO:0102134 biolink:MolecularActivity (22S)-22-hydroxy-campesterol C-23 hydroxylase activity Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O. MetaCyc:RXN-11529 go-plus.json http://purl.obolibrary.org/obo/GO_0102134 GO:0102137 biolink:MolecularActivity 7-oxateasterone synthase activity Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O. MetaCyc:RXN-11537 go-plus.json http://purl.obolibrary.org/obo/GO_0102137 GO:0102136 biolink:MolecularActivity 3-epi-6-deoxocathasterone C-23 hydroxylase activity Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + reduced (NADPH-hemoprotein reducdtase) + O2 = 6=deoxotyphasterol + oxidized (NADPH-hemoprotein reductase) + H2O. RHEA:27321|MetaCyc:RXN-11531|EC:1.14.14.147 go-plus.json http://purl.obolibrary.org/obo/GO_0102136 GO:0102139 biolink:MolecularActivity 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate. EC:3.7.1.13|RHEA:27870|MetaCyc:RXN-11543 go-plus.json http://purl.obolibrary.org/obo/GO_0102139 GO:0102138 biolink:MolecularActivity 7-oxatyphasterol synthase activity Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O. MetaCyc:RXN-11538 go-plus.json http://purl.obolibrary.org/obo/GO_0102138 GO:0102140 biolink:MolecularActivity heparan sulfate N-deacetylase activity Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine. MetaCyc:RXN-11557 go-plus.json http://purl.obolibrary.org/obo/GO_0102140 GO:0102142 biolink:MolecularActivity [dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate. MetaCyc:RXN-11561 go-plus.json http://purl.obolibrary.org/obo/GO_0102142 GO:0102141 biolink:MolecularActivity [chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate. MetaCyc:RXN-11560 go-plus.json http://purl.obolibrary.org/obo/GO_0102141 GO:0102144 biolink:MolecularActivity carboxyspermidine dehydrogenase II activity Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+. MetaCyc:RXN-11566|RHEA:34111 go-plus.json http://purl.obolibrary.org/obo/GO_0102144 GO:0102143 biolink:MolecularActivity carboxynorspermidine dehydrogenase I activity Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+. MetaCyc:RXN-11565|RHEA:34115 go-plus.json http://purl.obolibrary.org/obo/GO_0102143 GO:0102146 biolink:MolecularActivity tricetin O-methytransferase activity Catalysis of the reaction: tricetin + S-adenosyl-L-methionine = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine. RHEA:27493|MetaCyc:RXN-11582 go-plus.json http://purl.obolibrary.org/obo/GO_0102146 GO:0102145 biolink:MolecularActivity (3R)-(E)-nerolidol synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid. MetaCyc:RXN-11575|EC:4.2.3.49|RHEA:27534 go-plus.json http://purl.obolibrary.org/obo/GO_0102145 GO:0043401 biolink:BiologicalProcess steroid hormone mediated signaling pathway A series of molecular signals mediated by a steroid hormone binding to a receptor. go-plus.json steroid hormone mediated signalling http://purl.obolibrary.org/obo/GO_0043401 GO:0102148 biolink:MolecularActivity N-acetyl-beta-D-galactosaminidase activity Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan. MetaCyc:RXN-11622|EC:3.2.1.52 go-plus.json http://purl.obolibrary.org/obo/GO_0102148 GO:0043400 biolink:BiologicalProcess cortisol secretion The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland. go-plus.json hydrocortisone secretion http://purl.obolibrary.org/obo/GO_0043400 GO:0102147 biolink:MolecularActivity 3'-O-methyltricetin O methyl transferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin. RHEA:27497|MetaCyc:RXN-11583 go-plus.json http://purl.obolibrary.org/obo/GO_0102147 GO:0102149 biolink:MolecularActivity farnesylcysteine lyase activity Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide. MetaCyc:RXN-11623|EC:1.8.3.6|RHEA:30231 go-plus.json http://purl.obolibrary.org/obo/GO_0102149 CHEBI:83641 biolink:ChemicalSubstance juvenile hormone I go-plus.json http://purl.obolibrary.org/obo/CHEBI_83641 chebi_ph7_3 GO:0043407 biolink:BiologicalProcess negative regulation of MAP kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity. go-plus.json down regulation of MAPK activity|negative regulation of mitogen-activated protein kinase activity|downregulation of MAPK activity|down-regulation of MAPK activity|inhibition of MAPK activity|negative regulation of mitogen activated protein kinase activity http://purl.obolibrary.org/obo/GO_0043407 GO:0043406 biolink:BiologicalProcess positive regulation of MAP kinase activity Any process that activates or increases the frequency, rate or extent of MAP kinase activity. go-plus.json upregulation of MAPK activity|positive regulation of mitogen-activated protein kinase activity|up regulation of MAPK activity|stimulation of MAPK activity|positive regulation of mitogen activated protein kinase activity|up-regulation of MAPK activity http://purl.obolibrary.org/obo/GO_0043406 GO:0043409 biolink:BiologicalProcess negative regulation of MAPK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. go-plus.json negative regulation of mitogen-activated protein kinase kinase kinase cascade|down regulation of MAPKKK cascade|inhibition of MAPKKK cascade|negative regulation of MAP kinase cascade|downregulation of MAPK cascade|negative regulation of mitogen-activated protein kinase cascade|down regulation of MAPK cascade|inhibition of MAPK cascade|negative regulation of mitogen activated protein kinase kinase kinase cascade|down-regulation of MAPKKK cascade|negative regulation of mitogen activated protein kinase cascade|negative regulation of MAP kinase kinase kinase cascade|downregulation of MAPKKK cascade|negative regulation of MAPKKK cascade|down-regulation of MAPK cascade http://purl.obolibrary.org/obo/GO_0043409 GO:0043408 biolink:BiologicalProcess regulation of MAPK cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade. go-plus.json regulation of mitogen activated protein kinase cascade|regulation of MAP kinase kinase kinase cascade|regulation of MAPKKK cascade|regulation of mitogen-activated protein kinase kinase kinase cascade|regulation of MAP kinase cascade|regulation of mitogen-activated protein kinase cascade|regulation of mitogen activated protein kinase kinase kinase cascade http://purl.obolibrary.org/obo/GO_0043408 GO:0043403 biolink:BiologicalProcess skeletal muscle tissue regeneration The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. go-plus.json myofiber turnover http://purl.obolibrary.org/obo/GO_0043403 GO:0043402 biolink:BiologicalProcess glucocorticoid mediated signaling pathway A series of molecular signals mediated by the detection of a glucocorticoid hormone. go-plus.json glucocorticoid mediated signalling http://purl.obolibrary.org/obo/GO_0043402 GO:0043405 biolink:BiologicalProcess regulation of MAP kinase activity Any process that modulates the frequency, rate or extent of MAP kinase activity. go-plus.json regulation of mitogen activated protein kinase activity|Regulation of MAPK activity|regulation of mitogen-activated protein kinase activity http://purl.obolibrary.org/obo/GO_0043405 GO:0043404 biolink:MolecularActivity corticotropin-releasing hormone receptor activity Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity. go-plus.json corticotropin-releasing factor receptor activity|adrenocorticotropin-releasing hormone receptor activity|CRH receptor activity|CRF receptor activity http://purl.obolibrary.org/obo/GO_0043404 PR:000020789 biolink:Protein neuropeptide Y proteolytic cleavage product A neuropeptide Y that has been processed by proteolytic cleavage. go-plus.json NPY/ClvPrd http://purl.obolibrary.org/obo/PR_000020789 PR:000019798 biolink:Protein erythropoietin proteolytic cleavage product An erythropoietin that has been processed by proteolytic cleavage. go-plus.json EPO/ClvPrd http://purl.obolibrary.org/obo/PR_000019798 CHEBI:138393 biolink:ChemicalSubstance 7-oxotaurodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138393 CHEBI:138391 biolink:ChemicalSubstance 7-oxoglycolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138391 CHEBI:138390 biolink:ChemicalSubstance EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_138390 GO:0043410 biolink:BiologicalProcess positive regulation of MAPK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. go-plus.json activation of MAPK cascade|up-regulation of MAPK cascade|stimulation of MAPK cascade|up regulation of MAPKKK cascade|positive regulation of MAP kinase kinase kinase cascade|positive regulation of MAPKKK cascade|positive regulation of mitogen-activated protein kinase kinase kinase cascade|upregulation of MAPKKK cascade|positive regulation of MAP kinase cascade|stimulation of MAPKKK cascade|up-regulation of MAPKKK cascade|positive regulation of mitogen-activated protein kinase cascade|activation of MAPKKK cascade|upregulation of MAPK cascade|positive regulation of mitogen activated protein kinase kinase kinase cascade http://purl.obolibrary.org/obo/GO_0043410 GO:0043412 biolink:BiologicalProcess macromolecule modification The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. go-plus.json http://purl.obolibrary.org/obo/GO_0043412 goslim_pir GO:0043411 biolink:MolecularActivity obsolete myopalladin binding OBSOLETE. Binding to myopalladin, a myofibrillar protein with titin-like Ig domains. go-plus.json myopalladin binding http://purl.obolibrary.org/obo/GO_0043411 GO:0043418 biolink:BiologicalProcess homocysteine catabolic process The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. go-plus.json homocysteine degradation|homocysteine breakdown|homocysteine catabolism http://purl.obolibrary.org/obo/GO_0043418 GO:0043417 biolink:BiologicalProcess negative regulation of skeletal muscle tissue regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration. go-plus.json down-regulation of skeletal muscle regeneration|downregulation of skeletal muscle regeneration|down regulation of skeletal muscle regeneration|inhibition of skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0043417 OBO:uberon/core#transitively_proximally_connected_to biolink:OntologyClass transitively proximally connected to . transitively_proximally_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to GO:0043419 biolink:BiologicalProcess urea catabolic process The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2. go-plus.json urea decomposition|urea degradation|urea breakdown|urea catabolism http://purl.obolibrary.org/obo/GO_0043419 GO:0043414 biolink:BiologicalProcess macromolecule methylation The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043414 GO:0043413 biolink:BiologicalProcess macromolecule glycosylation The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043413 GO:0043416 biolink:BiologicalProcess regulation of skeletal muscle tissue regeneration Any process that modulates the frequency, rate or extent of skeletal muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0043416 GO:0043415 biolink:BiologicalProcess positive regulation of skeletal muscle tissue regeneration Any process that activates or increase the rate of skeletal muscle regeneration. go-plus.json upregulation of skeletal muscle regeneration|stimulation of skeletal muscle regeneration|activation of skeletal muscle regeneration|up-regulation of skeletal muscle regeneration|up regulation of skeletal muscle regeneration http://purl.obolibrary.org/obo/GO_0043415 NCBITaxon:224911 biolink:OrganismalEntity Bradyrhizobium diazoefficiens USDA 110 go-plus.json Bradyrhizobium japonicum USDA 110 http://purl.obolibrary.org/obo/NCBITaxon_224911 CHEBI:138386 biolink:ChemicalSubstance TDP-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_138386 CHEBI:138385 biolink:ChemicalSubstance N(omega)-(2'-phospho-ADP-D-ribosyl)-L-arginine(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138385 chebi_ph7_3 CHEBI:138384 biolink:ChemicalSubstance 7-oxotaurolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138384 CHEBI:138383 biolink:ChemicalSubstance (4S,7R)-7-isopropyl-4-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138383 chebi_ph7_3 CHEBI:138389 biolink:ChemicalSubstance 7,12-dioxolithocholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138389 CHEBI:138388 biolink:ChemicalSubstance 4-methylpent-3-en-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138388 chebi_ph7_3 PR:000020775 biolink:Protein atrial natriuretic factor proteolytic cleavage product An atrial natriuretic factor that has been processed by proteolytic cleavage. go-plus.json NPPA/ClvPrd http://purl.obolibrary.org/obo/PR_000020775 GO:0043421 biolink:BiologicalProcess anthranilate catabolic process The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate). MetaCyc:2AMINOBENZDEG-PWY go-plus.json ortho-aminobenzoic acid catabolism|anthranilic acid catabolic process|2-aminobenzoate catabolism|anthranilate catabolism|2-aminobenzoate degradation|anthranilate degradation|2-aminobenzoate breakdown|2-aminobenzoate catabolic process|anthranilic acid catabolism|anthranilate breakdown|ortho-aminobenzoic acid catabolic process http://purl.obolibrary.org/obo/GO_0043421 GO:0043420 biolink:BiologicalProcess anthranilate metabolic process The chemical reactions and pathways involving anthranilate (2-aminobenzoate). UM-BBD_pathwayID:abz2 go-plus.json anthranilic acid metabolism|anthranilic acid metabolic process|ortho-aminobenzoic acid metabolism|2-aminobenzoate metabolic process|anthranilate metabolism|ortho-aminobenzoic acid metabolic process|2-aminobenzoate metabolism http://purl.obolibrary.org/obo/GO_0043420 GO:0043423 biolink:MolecularActivity 3-phosphoinositide-dependent protein kinase binding Binding to a 3-phosphoinositide-dependent protein kinase. go-plus.json phosphatidylinositol-3-phosphate-dependent protein kinase binding http://purl.obolibrary.org/obo/GO_0043423 GO:0043422 biolink:MolecularActivity protein kinase B binding Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism. go-plus.json PKB binding|Akt binding http://purl.obolibrary.org/obo/GO_0043422 CHEBI:83665 biolink:ChemicalSubstance lysidine monophosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83665 chebi_ph7_3 CHEBI:83664 biolink:ChemicalSubstance lysine monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83664 GO:0043429 biolink:MolecularActivity 2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. go-plus.json 2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity http://purl.obolibrary.org/obo/GO_0043429 CHEBI:83662 biolink:ChemicalSubstance lysidine monophosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83662 chebi_ph7_3 GO:0043428 biolink:MolecularActivity 2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. MetaCyc:RXN-9227|RHEA:44756 go-plus.json 2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity http://purl.obolibrary.org/obo/GO_0043428 CHEBI:83661 biolink:ChemicalSubstance lysidine monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83661 GO:0043425 biolink:MolecularActivity bHLH transcription factor binding Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0043425 GO:0043424 biolink:MolecularActivity protein histidine kinase binding Binding to a protein histidine kinase. go-plus.json protein-histidine kinase binding|histidine-protein kinase binding|histidine kinase binding http://purl.obolibrary.org/obo/GO_0043424 GO:0043427 biolink:BiologicalProcess carbon fixation by 3-hydroxypropionate cycle An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product. go-plus.json 3-hydroxypropionate pathway|3-hydroxypropionate cycle|hydroxypropionate pathway|hydroxypropionate cycle http://purl.obolibrary.org/obo/GO_0043427 GO:0043426 biolink:MolecularActivity MRF binding Binding to Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors. go-plus.json MyoD binding|Myf5 binding|Mrf4 binding|myogenin binding http://purl.obolibrary.org/obo/GO_0043426 CHEBI:138397 biolink:ChemicalSubstance octahydronaphthalenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_138397 CHEBI:138396 biolink:ChemicalSubstance OPC8-CoA (4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138396 chebi_ph7_3 CHEBI:138394 biolink:ChemicalSubstance 7-oxoglycodeoxycholic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138394 CHEBI:138399 biolink:ChemicalSubstance 7beta-hydroxy-3,12-dioxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138399 CHEBI:138398 biolink:ChemicalSubstance (15Z)-12-oxophyto-10,15-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138398 chebi_ph7_3 CHEBI:138371 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_138371 chebi_ph7_3 CHEBI:138370 biolink:ChemicalSubstance N(6)-(gamma-glutamyl)lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138370 chebi_ph7_3 GO:0043432 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043432 GO:0043431 biolink:MolecularActivity 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine. MetaCyc:2.1.1.64-RXN go-plus.json 3-demethylubiquinone-9 3-methyltransferase activity|2-octaprenyl-6-hydroxy phenol methylase activity http://purl.obolibrary.org/obo/GO_0043431 GO:0043434 biolink:BiologicalProcess response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. go-plus.json response to polypeptide hormone stimulus|response to peptide hormone stimulus http://purl.obolibrary.org/obo/GO_0043434 GO:0043433 biolink:BiologicalProcess negative regulation of DNA-binding transcription factor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. go-plus.json negative regulation of thyroid hormone receptor activity|down-regulation of transcription factor activity|negative regulation of transcription factor activity|negative regulation of androgen receptor activity|negative regulation of DNA binding transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|inhibition of transcription factor activity|down regulation of transcription factor activity|downregulation of transcription factor activity http://purl.obolibrary.org/obo/GO_0043433 CHEBI:83677 biolink:ChemicalSubstance 12-PAHSA(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83677 chebi_ph7_3 GO:0043430 biolink:MolecularActivity 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. RHEA:44764|Reactome:R-HSA-2162188 go-plus.json 2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity http://purl.obolibrary.org/obo/GO_0043430 GO:0043439 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043439 CHEBI:83670 biolink:ChemicalSubstance 9-PAHSA(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83670 chebi_ph7_3 CHEBI:138369 biolink:ChemicalSubstance [4)-beta-D-GlcA-(1->4)-beta-D-GlcA2(or 3)Ac-(1->4)-beta-D-Glc-(1->4)-[(R)-4,6-CH3(COO(-))C-beta-D-Gal3(or 2)OHb-(1->3)-beta-D-Glc-(1->4)-beta-D-Glc-(1->4)-beta-D-Glc-(1->6)]-alpha-DGlc2(or 3)Ac-(1->]n go-plus.json http://purl.obolibrary.org/obo/CHEBI_138369 chebi_ph7_3 GO:0043436 biolink:BiologicalProcess oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). go-plus.json oxo acid metabolic process|ketoacid metabolism|ketoacid metabolic process|oxo acid metabolism|keto acid metabolic process|oxoacid metabolism|keto acid metabolism http://purl.obolibrary.org/obo/GO_0043436 GO:0043435 biolink:BiologicalProcess response to corticotropin-releasing hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response. go-plus.json response to CRF stimulus|response to CRH stimulus|response to corticotropin-releasing factor stimulus|response to corticoliberin stimulus|response to corticotropin-releasing hormone stimulus http://purl.obolibrary.org/obo/GO_0043435 GO:0043438 biolink:BiologicalProcess acetoacetic acid metabolic process The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH. go-plus.json beta-ketobutyric acid metabolic process|diacetic acid metabolism|beta ketobutyric acid metabolism|3-oxobutanoic acid metabolic process|acetoacetic acid metabolism|3-oxobutanoic acid metabolism|beta ketobutyric acid metabolic process|diacetic acid metabolic process|beta-ketobutyric acid metabolism|3-oxobutanoate metabolic process|acetoacetate metabolic process|acetoacetate metabolism|3-oxobutanoate metabolism http://purl.obolibrary.org/obo/GO_0043438 GO:0043437 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043437 CHEBI:138363 biolink:ChemicalSubstance (4R,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138363 chebi_ph7_3 CHEBI:138362 biolink:ChemicalSubstance (4S,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138362 chebi_ph7_3 CHEBI:138361 biolink:ChemicalSubstance 2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138361 CHEBI:138366 biolink:ChemicalSubstance bile acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_138366 CHEBI:138365 biolink:ChemicalSubstance allo-bile acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138365 GO:0102100 biolink:MolecularActivity mycothiol-arsenate ligase activity Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O. EC:2.8.4.2|MetaCyc:RXN-11187|RHEA:27349 go-plus.json http://purl.obolibrary.org/obo/GO_0102100 GO:0102102 biolink:MolecularActivity homocarnosine synthase activity Catalysis of the reaction: gamma-aminobutyric acid + L-histidine + ATP = H+ + homocarnosine + ADP + hydrogenphosphate. EC:6.3.2.11|RHEA:59568|MetaCyc:RXN-11222 go-plus.json http://purl.obolibrary.org/obo/GO_0102102 GO:0043443 biolink:BiologicalProcess acetone metabolic process The chemical reactions and pathways involving acetone, propan-2-one. go-plus.json dimethyl ketone metabolism|2-propanone metabolic process|propan-2-one metabolism|acetone metabolism|propan-2-one metabolic process|2-propanone metabolism|dimethyl ketone metabolic process http://purl.obolibrary.org/obo/GO_0043443 GO:0102101 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102101 GO:0043442 biolink:BiologicalProcess acetoacetic acid catabolic process The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH. go-plus.json acetoacetic acid catabolism|acetoacetic acid degradation|acetoacetic acid breakdown http://purl.obolibrary.org/obo/GO_0043442 GO:0043445 biolink:BiologicalProcess acetone biosynthetic process The chemical reactions and pathways resulting in the formation of acetone, propan-2-one. go-plus.json acetone synthesis|acetone formation|dimethyl ketone biosynthesis|dimethyl ketone biosynthetic process|propan-2-one biosynthesis|propan-2-one biosynthetic process|acetone biosynthesis|2-propanone biosynthetic process|2-propanone biosynthesis|acetone anabolism http://purl.obolibrary.org/obo/GO_0043445 GO:0102104 biolink:MolecularActivity demethoxycurcumin synthase activity Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide. MetaCyc:RXN-11224 go-plus.json http://purl.obolibrary.org/obo/GO_0102104 GO:0043444 biolink:BiologicalProcess acetone catabolic process The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one. go-plus.json propan-2-one catabolic process|dimethyl ketone catabolism|dimethyl ketone catabolic process|propan-2-one catabolism|acetone degradation|acetone catabolism|2-propanone catabolic process|acetone breakdown|2-propanone catabolism http://purl.obolibrary.org/obo/GO_0043444 GO:0102103 biolink:MolecularActivity demethoxycurcumin synthase Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide. EC:2.3.1.219|MetaCyc:RXN-11223|RHEA:35119 go-plus.json http://purl.obolibrary.org/obo/GO_0102103 GO:0102106 biolink:MolecularActivity curcumin synthase activity Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O <=> curcumin + 2 coenzyme A(4-) + carbon dioxide. EC:2.3.1.217|MetaCyc:RXN-11226|RHEA:34823 go-plus.json http://purl.obolibrary.org/obo/GO_0102106 GO:0102105 biolink:MolecularActivity demethoxycurcumin synthase activity from feruloylacetyl-CoA Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide. EC:2.3.1.219|MetaCyc:RXN-11225|RHEA:35139 go-plus.json http://purl.obolibrary.org/obo/GO_0102105 GO:0043441 biolink:BiologicalProcess acetoacetic acid biosynthetic process The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH. go-plus.json acetoacetic acid synthesis|acetoacetic acid formation|acetoacetic acid biosynthesis|acetoacetic acid anabolism http://purl.obolibrary.org/obo/GO_0043441 GO:0043440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043440 GO:0102109 biolink:MolecularActivity tricaffeoyl spermidine O-methyltransferase activity Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine. MetaCyc:RXN-11261 go-plus.json http://purl.obolibrary.org/obo/GO_0102109 CHEBI:83683 biolink:ChemicalSubstance N-terminal N-acetyl-L-alanine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83683 chebi_ph7_3 GO:0043447 biolink:BiologicalProcess alkane biosynthetic process The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2. go-plus.json alkane synthesis|alkane formation|alkane biosynthesis|alkane anabolism http://purl.obolibrary.org/obo/GO_0043447 GO:0043446 biolink:BiologicalProcess cellular alkane metabolic process The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells. go-plus.json alkane metabolism http://purl.obolibrary.org/obo/GO_0043446 goslim_pir GO:0043449 biolink:BiologicalProcess cellular alkene metabolic process The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells. go-plus.json alkene metabolism http://purl.obolibrary.org/obo/GO_0043449 goslim_pir GO:0043448 biolink:BiologicalProcess alkane catabolic process The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2. go-plus.json alkane degradation|alkane breakdown|alkane catabolism http://purl.obolibrary.org/obo/GO_0043448 CHEBI:138375 biolink:ChemicalSubstance (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138375 chebi_ph7_3 CHEBI:138374 biolink:ChemicalSubstance N-(12-hydroxyjasmonyl)-L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138374 chebi_ph7_3 CHEBI:138373 biolink:ChemicalSubstance 4-methylpent-3-en-1-yl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138373 chebi_ph7_3 OBO:GOCHE_25944 biolink:OntologyClass substance with pesticide role go-plus.json http://purl.obolibrary.org/obo/GOCHE_25944 3_STAR CHEBI:138372 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_138372 chebi_ph7_3 CHEBI:138379 biolink:ChemicalSubstance ursodeoxycholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138379 CHEBI:138378 biolink:ChemicalSubstance beta-muricholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138378 CHEBI:138377 biolink:ChemicalSubstance allodeoxycholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138377 CHEBI:138376 biolink:ChemicalSubstance allocholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138376 GO:0102193 biolink:MolecularActivity protein-ribulosamine 3-kinase activity Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine. RHEA:48432|EC:2.7.1.172|MetaCyc:RXN-12003 go-plus.json http://purl.obolibrary.org/obo/GO_0102193 GO:0102192 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102192 GO:0102195 biolink:MolecularActivity UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+. RHEA:25273|MetaCyc:RXN-12042|EC:6.3.2.37 go-plus.json http://purl.obolibrary.org/obo/GO_0102195 GO:0102194 biolink:MolecularActivity protein-fructosamine 3-kinase activity Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine. RHEA:59832|EC:2.7.1.171|MetaCyc:RXN-12005 go-plus.json fructosamine-3-kinase activity http://purl.obolibrary.org/obo/GO_0102194 GO:0102197 biolink:MolecularActivity vinylacetate caboxylester hydrolase activity Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate. MetaCyc:RXN-12087 go-plus.json http://purl.obolibrary.org/obo/GO_0102197 GO:0102196 biolink:MolecularActivity cortisol dehydrogenase activity Catalysis of the reaction: cortisol + NADP <=> cortisone + NADPH + H+. MetaCyc:RXN-12085 go-plus.json http://purl.obolibrary.org/obo/GO_0102196 GO:0102199 biolink:MolecularActivity nitric oxide reductase activity (NAD(P)H-dependent) activity Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H. MetaCyc:RXN-12112|EC:1.7.1.14 go-plus.json http://purl.obolibrary.org/obo/GO_0102199 UBERON:0015030 biolink:AnatomicalEntity pedal digit phalanx endochondral element A pedal digit phalanx bone or its cartilage or pre-cartilage precursor. go-plus.json pedal digit phalanx skeletal element|pedal digit phalanx element http://purl.obolibrary.org/obo/UBERON_0015030 GO:0102198 biolink:MolecularActivity L-idonate 5-dehydrogenase activity (NAD-dependent) Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+. RHEA:21172|EC:1.1.1.366|MetaCyc:RXN-12107 go-plus.json http://purl.obolibrary.org/obo/GO_0102198 UBERON:0015036 biolink:AnatomicalEntity pedal digit metatarsal endochondral element A pedal digit metatarsal bone or its cartilage or pre-cartilage precursor. go-plus.json pedal digit metatarsal element|pedal digit metatarsal skeletal element http://purl.obolibrary.org/obo/UBERON_0015036 CHEBI:222169 biolink:ChemicalSubstance (S)-nipecotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_222169 OBA:VT0000056 biolink:OntologyClass urine trait The quality when measured in urine. go-plus.json http://purl.obolibrary.org/obo/OBA_VT0000056 UBERON:0015021 biolink:AnatomicalEntity forelimb endochondral element A forelimb bone or its cartilage or pre-cartilage precursor. go-plus.json forelimb skeletal element http://purl.obolibrary.org/obo/UBERON_0015021 UBERON:0015023 biolink:AnatomicalEntity phalanx endochondral element A phalanx bone or its cartilage or pre-cartilage precursor. go-plus.json phalanx element|phalanx skeletal element http://purl.obolibrary.org/obo/UBERON_0015023 UBERON:0015022 biolink:AnatomicalEntity hindlimb endochondral element A hindlimb bone or its cartilage or pre-cartilage precursor. go-plus.json hindlimb bone skeletal element http://purl.obolibrary.org/obo/UBERON_0015022 UBERON:0015024 biolink:AnatomicalEntity manual digit phalanx endochondral element A manual digit phalanx bone or its cartilage or pre-cartilage precursor. go-plus.json manual digit phalanx element|manual digit phalanx skeletal element http://purl.obolibrary.org/obo/UBERON_0015024 UBERON:0015019 biolink:AnatomicalEntity rib endochondral element A rib bone or its cartilage or pre-cartilage precursor. go-plus.json rib element|rib skeletal element http://purl.obolibrary.org/obo/UBERON_0015019 UBERON:0015013 biolink:AnatomicalEntity fibula endochondral element The major postaxial endochondral element in the posterior zeugopod[Phenoscape]. go-plus.json fibula element|fibula skeletal element http://purl.obolibrary.org/obo/UBERON_0015013 UBERON:0005691 biolink:AnatomicalEntity 4th arch mesenchyme Mesenchyme that is part of a pharyngeal arch 4. go-plus.json 4th pharyngeal arch mesenchyme|4th branchial arch mesenchyme|pharyngeal arch 4 mesenchyme http://purl.obolibrary.org/obo/UBERON_0005691 UBERON:0005690 biolink:AnatomicalEntity 3rd arch mesenchyme Mesenchyme that is part of a pharyngeal arch 3. go-plus.json 3rd pharyngeal arch mesenchyme|3rd branchial arch mesenchyme|pharyngeal arch 3 mesenchyme http://purl.obolibrary.org/obo/UBERON_0005690 UBERON:0015007 biolink:AnatomicalEntity cervical vertebra endochondral element A vertebral endochondral element in the cervical region of the vertebral column. go-plus.json cervical vertebra skeletal element|cervical vertebra element http://purl.obolibrary.org/obo/UBERON_0015007 UBERON:0015008 biolink:AnatomicalEntity thoracic vertebra endochondral element A vertebral endochondral element in the thoracic region of the vertebral column. go-plus.json thoracic vertebra skeletal element|thoracic vertebra element http://purl.obolibrary.org/obo/UBERON_0015008 UBERON:0015004 biolink:AnatomicalEntity tibia endochondral element The major preaxial endochondral element in the posterior zeugopod[Phenoscape]. go-plus.json tibia skeletal element|tibia element http://purl.obolibrary.org/obo/UBERON_0015004 CHEBI:10642 biolink:ChemicalSubstance scyllo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_10642 chebi_ph7_3 UBERON:0005689 biolink:AnatomicalEntity 2nd arch mesenchyme Mesenchyme that is part of a pharyngeal arch 2. go-plus.json 2nd branchial arch mesenchyme|pharyngeal arch 2 mesenchyme|2nd pharyngeal arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0005689 UBERON:0005688 biolink:AnatomicalEntity lens vesicle cavity An anatomical cavity that is part of a lens vesicle. go-plus.json lens cavity|cavity of lens vesicle|cavity of lens http://purl.obolibrary.org/obo/UBERON_0005688 UBERON:0005687 biolink:AnatomicalEntity orbitosphenoid cartilage element A orbitosphenoid endochondral element that is composed primarily of cartilage tissue. go-plus.json sphenoid lesser wing cartilage element http://purl.obolibrary.org/obo/UBERON_0005687 UBERON:0005686 biolink:AnatomicalEntity caecum dorsal mesentery A dorsal mesentery that is part of a caecum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005686 UBERON:0005685 biolink:AnatomicalEntity midgut dorsal mesentery A dorsal mesentery that is part of a midgut. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005685 GO:0102151 biolink:MolecularActivity 3-oxo-myristate decarboxylase activity Catalysis of the reaction: 3-oxo-myristate + H+ <=> 2-tridecanone + carbon dioxide. EC:4.1.1.56|MetaCyc:RXN-11669 go-plus.json http://purl.obolibrary.org/obo/GO_0102151 UBERON:0015078 biolink:AnatomicalEntity proximal carpal endochondral element A proximal mesopodial endochondral element that is part of a forelimb. go-plus.json proximal carpal element|proximal carpal http://purl.obolibrary.org/obo/UBERON_0015078 GO:0102150 biolink:MolecularActivity 3-oxo-myristoyl-CoA hydrolase activity Catalysis of the reaction: 3-oxotetradecanoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+. MetaCyc:RXN-11668 go-plus.json http://purl.obolibrary.org/obo/GO_0102150 GO:0102152 biolink:MolecularActivity Delta12-linoleate epoxygenase activity Catalysis of the reaction: H+ + 1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP + H2O. MetaCyc:RXN-11671 go-plus.json http://purl.obolibrary.org/obo/GO_0102152 GO:0102155 biolink:MolecularActivity S-sulfolactate dehydrogenase activity Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+. MetaCyc:RXN-11689|EC:1.1.1.310|RHEA:28194 go-plus.json http://purl.obolibrary.org/obo/GO_0102155 GO:0102154 biolink:MolecularActivity 8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+. MetaCyc:RXN-11685 go-plus.json http://purl.obolibrary.org/obo/GO_0102154 GO:0102157 biolink:MolecularActivity (R)-sulfopropanediol 2-dehydrogenase activity Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+. MetaCyc:RXN-11729 go-plus.json http://purl.obolibrary.org/obo/GO_0102157 GO:0102156 biolink:MolecularActivity 2,5-DHBA UDP-glucosyltransferase activity Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+. MetaCyc:RXN-11705 go-plus.json http://purl.obolibrary.org/obo/GO_0102156 GO:0102159 biolink:MolecularActivity baicalein 7-O-glucuronosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin. RHEA:28314|EC:2.4.1.253|MetaCyc:RXN-11755 go-plus.json http://purl.obolibrary.org/obo/GO_0102159 GO:0102158 biolink:MolecularActivity very-long-chain 3-hydroxyacyl-CoA dehydratase activity Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain trans-2,3-dehydroacyl-CoA. RHEA:45812|EC:4.2.1.134|MetaCyc:RXN-11750 go-plus.json http://purl.obolibrary.org/obo/GO_0102158 UBERON:0015079 biolink:AnatomicalEntity proximal carpal cartilage A proximal carpal endochondral element that is composed primarily of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015079 NCBITaxon:7214 biolink:OrganismalEntity Drosophilidae go-plus.json pomace flies http://purl.obolibrary.org/obo/NCBITaxon_7214 GO:0102160 biolink:MolecularActivity cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP. RHEA:28258|EC:2.4.1.254|MetaCyc:RXN-11756 go-plus.json http://purl.obolibrary.org/obo/GO_0102160 UBERON:0015064 biolink:AnatomicalEntity autopod cartilage A autopod endochondral element that is composed primarily of cartilage tissue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015064 GO:0102162 biolink:MolecularActivity all-trans-8'-apo-beta-carotenal 15,15'-oxygenase Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial. MetaCyc:RXN-11783|EC:1.13.11.75|RHEA:26385 go-plus.json http://purl.obolibrary.org/obo/GO_0102162 GO:0102161 biolink:MolecularActivity copal-8-ol diphosphate synthase activity Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O. MetaCyc:RXN-11772|RHEA:32703|EC:4.2.1.133 go-plus.json http://purl.obolibrary.org/obo/GO_0102161 GO:0102164 biolink:MolecularActivity 2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O. EC:1.14.13.182|RHEA:37871|MetaCyc:RXN-11849 go-plus.json http://purl.obolibrary.org/obo/GO_0102164 UBERON:0015061 biolink:AnatomicalEntity limb endochondral element A limb bone or its cartilage or pre-cartilage precursor. go-plus.json limb bone endochondral element|limb bone skeletal element http://purl.obolibrary.org/obo/UBERON_0015061 GO:0102163 biolink:MolecularActivity 3-hydroxyacyl-CoA-acyl carrier protein transferase activity Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein]. MetaCyc:RXN-11785 go-plus.json http://purl.obolibrary.org/obo/GO_0102163 UBERON:0015060 biolink:AnatomicalEntity sphenoid endochondral element A sphenoid bone or its cartilage or pre-cartilage precursor. go-plus.json sphenoid bone skeletal element|sphenoid element http://purl.obolibrary.org/obo/UBERON_0015060 UBERON:0015063 biolink:AnatomicalEntity autopod endochondral element A endochondral element that is part of a autopod region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015063 GO:0102166 biolink:MolecularActivity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-threonine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-threonine. MetaCyc:RXN-11891|RHEA:48892|EC:3.2.1.169 go-plus.json http://purl.obolibrary.org/obo/GO_0102166 GO:0102165 biolink:MolecularActivity (Z)-3-hexen-1-ol acetyltransferase activity Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol <=> (3Z)-hex-3-en-1-yl acetate + coenzyme A. MetaCyc:RXN-11852|EC:2.3.1.195|RHEA:28254 go-plus.json http://purl.obolibrary.org/obo/GO_0102165 NCBITaxon:7215 biolink:OrganismalEntity Drosophila go-plus.json Drosophila|fruit fly|fruit flies http://purl.obolibrary.org/obo/NCBITaxon_7215 GO:0102168 biolink:MolecularActivity 5-methyl-phenazine-1-carboxylate N-methyltransferase activity Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine. MetaCyc:RXN-11897|RHEA:49112 go-plus.json http://purl.obolibrary.org/obo/GO_0102168 GO:0102167 biolink:MolecularActivity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine. MetaCyc:RXN-11892|RHEA:48876|EC:3.2.1.169 go-plus.json http://purl.obolibrary.org/obo/GO_0102167 GO:0102169 biolink:MolecularActivity pyocyanin hydroxylase activity Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ <=> pyocyanin + NAD + carbon dioxide + H2O. MetaCyc:RXN-11898|RHEA:48976 go-plus.json http://purl.obolibrary.org/obo/GO_0102169 GO:0102171 biolink:MolecularActivity DMNT synthase activity Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O. MetaCyc:RXN-11911|RHEA:55424 go-plus.json http://purl.obolibrary.org/obo/GO_0102171 GO:0102170 biolink:MolecularActivity 5-epi-aristolochene-1,3-dihydroxylase activity Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 <=> capsidiol + 2 NADP + 2 H2O. MetaCyc:RXN-11908|RHEA:28226|EC:1.14.14.149 go-plus.json http://purl.obolibrary.org/obo/GO_0102170 UBERON:0015053 biolink:AnatomicalEntity humerus endochondral element A humerus bone or its cartilage or pre-cartilage precursor. go-plus.json humerus skeletal element|humerus element http://purl.obolibrary.org/obo/UBERON_0015053 GO:0102173 biolink:MolecularActivity 24-methylenecycloartanol 4alpha-methyl oxidase activity Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O. MetaCyc:RXN-11926|RHEA:58836 go-plus.json http://purl.obolibrary.org/obo/GO_0102173 OBO:chebi#has_parent_hydride biolink:OntologyClass has parent hydride go-plus.json http://purl.obolibrary.org/obo/chebi#has_parent_hydride GO:0102172 biolink:MolecularActivity 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O. RHEA:58860|MetaCyc:RXN-11925 go-plus.json http://purl.obolibrary.org/obo/GO_0102172 GO:0102175 biolink:MolecularActivity 3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity Catalysis of the reaction: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH. RHEA:34775|MetaCyc:RXN-11928 go-plus.json http://purl.obolibrary.org/obo/GO_0102175 UBERON:0015050 biolink:AnatomicalEntity tarsus endochondral element A tarsus bone or its cartilage or pre-cartilage precursor. go-plus.json tarsus skeletal element|tarsus element http://purl.obolibrary.org/obo/UBERON_0015050 GO:0102174 biolink:MolecularActivity 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O. RHEA:58864|MetaCyc:RXN-11927 go-plus.json http://purl.obolibrary.org/obo/GO_0102174 GO:0102177 biolink:MolecularActivity 24-methylenelophenol methyl oxidase activity Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O. RHEA:58872|MetaCyc:RXN-11930 go-plus.json http://purl.obolibrary.org/obo/GO_0102177 UBERON:0015052 biolink:AnatomicalEntity femur endochondral element A femur bone or its cartilage or pre-cartilage precursor. go-plus.json femur skeletal element|femur element http://purl.obolibrary.org/obo/UBERON_0015052 GO:0102176 biolink:MolecularActivity cycloeucalenone reductase activity Catalysis of the reaction: cycloeucalenone + NADPH + H+ <=> cycloeucalenol + NADP. MetaCyc:RXN-11929|EC:1.1.1.270 go-plus.json http://purl.obolibrary.org/obo/GO_0102176 GO:0102179 biolink:MolecularActivity 24-ethylidenelophenol 4alpha-methyl oxidase activity Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O. MetaCyc:RXN-11935|RHEA:59032 go-plus.json http://purl.obolibrary.org/obo/GO_0102179 CHEBI:10615 biolink:ChemicalSubstance omega-hydroxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_10615 GO:0102178 biolink:MolecularActivity 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O. RHEA:58880|MetaCyc:RXN-11932 go-plus.json http://purl.obolibrary.org/obo/GO_0102178 UBERON:0015057 biolink:AnatomicalEntity scapula endochondral element A scapula bone or its cartilage or pre-cartilage precursor. go-plus.json scapula skeletal element|scapula element http://purl.obolibrary.org/obo/UBERON_0015057 UBERON:0015059 biolink:AnatomicalEntity orbitosphenoid endochondral element A orbitosphenoid bone or its cartilage or pre-cartilage precursor. go-plus.json orbitosphenoid element|orbitosphenoid skeletal element http://purl.obolibrary.org/obo/UBERON_0015059 GO:0102180 biolink:MolecularActivity 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O. RHEA:59036|MetaCyc:RXN-11936 go-plus.json http://purl.obolibrary.org/obo/GO_0102180 GO:0102182 biolink:MolecularActivity 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide. MetaCyc:RXN-11938 go-plus.json http://purl.obolibrary.org/obo/GO_0102182 UBERON:0015042 biolink:AnatomicalEntity manual digit metacarpus endochondral element A manual digit metacarpus bone or its cartilage or pre-cartilage precursor. go-plus.json manual digit metacarpus element|manual digit metacarpus skeletal element http://purl.obolibrary.org/obo/UBERON_0015042 GO:0102181 biolink:MolecularActivity 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O. MetaCyc:RXN-11937|RHEA:59040 go-plus.json http://purl.obolibrary.org/obo/GO_0102181 GO:0102184 biolink:MolecularActivity cycloartenol 4alpha-methyl oxidase activity Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O. MetaCyc:RXN-11946 go-plus.json http://purl.obolibrary.org/obo/GO_0102184 GO:0102183 biolink:MolecularActivity avenastenone reductase activity Catalysis of the reaction: avenastenone + NADPH + H+ <=> avenasterol + NADP. MetaCyc:RXN-11939 go-plus.json http://purl.obolibrary.org/obo/GO_0102183 GO:0102186 biolink:MolecularActivity 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 <=> 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + H2O. MetaCyc:RXN-11948 go-plus.json http://purl.obolibrary.org/obo/GO_0102186 GO:0102185 biolink:MolecularActivity 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + 2 H2O. MetaCyc:RXN-11947 go-plus.json http://purl.obolibrary.org/obo/GO_0102185 GO:0102188 biolink:MolecularActivity 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O. MetaCyc:RXN-11956 go-plus.json http://purl.obolibrary.org/obo/GO_0102188 GO:0102187 biolink:MolecularActivity 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol dehydrogenase/C4-decarboxylase activity Catalysis of the reaction: 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) <=> 4alpha,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3-one + NADH(2-) + carbon dioxide. MetaCyc:RXN-11949 go-plus.json http://purl.obolibrary.org/obo/GO_0102187 GO:0102189 biolink:MolecularActivity 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + 2 H2O. MetaCyc:RXN-11957 go-plus.json http://purl.obolibrary.org/obo/GO_0102189 UBERON:0015049 biolink:AnatomicalEntity carpus endochondral element A carpus bone or its cartilage or pre-cartilage precursor. go-plus.json carpus element|carpus skeletal element http://purl.obolibrary.org/obo/UBERON_0015049 NCBITaxon:7203 biolink:OrganismalEntity Brachycera go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7203 NCBITaxon:200918 biolink:OrganismalEntity Thermotogae go-plus.json Thermotogaeota|Thermotogota|Thermotogae http://purl.obolibrary.org/obo/NCBITaxon_200918 GO:0102191 biolink:MolecularActivity 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol dehydrogenase/C4-decarboxylase activity Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) <=> 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide. RHEA:59016|EC:1.1.1.418|MetaCyc:RXN-11959 go-plus.json http://purl.obolibrary.org/obo/GO_0102191 GO:0102190 biolink:MolecularActivity 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O. MetaCyc:RXN-11958 go-plus.json http://purl.obolibrary.org/obo/GO_0102190 UBERON:0005629 biolink:AnatomicalEntity vascular plexus A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part. go-plus.json plexus vasculosus http://purl.obolibrary.org/obo/UBERON_0005629 GO:0018407 biolink:BiologicalProcess peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine). RESID:AA0177 go-plus.json peptidyl-thyronine iodination to form triiodothyronine http://purl.obolibrary.org/obo/GO_0018407 GO:0018406 biolink:BiologicalProcess protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring. RESID:AA0217 go-plus.json protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan|protein amino acid C-linked mannosylation http://purl.obolibrary.org/obo/GO_0018406 GO:0018409 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018409 GO:0018408 biolink:BiologicalProcess peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine). RESID:AA0178 go-plus.json http://purl.obolibrary.org/obo/GO_0018408 GO:0018403 biolink:BiologicalProcess protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues. RESID:AA0209 go-plus.json protein-dermatan sulphate linkage via dermatan 4-sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine http://purl.obolibrary.org/obo/GO_0018403 GO:0018402 biolink:BiologicalProcess protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues. RESID:AA0208 go-plus.json protein-chondroitin sulphate linkage via chondroitin sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine http://purl.obolibrary.org/obo/GO_0018402 CHEBI:34687 biolink:ChemicalSubstance dibutyl phthalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_34687 chebi_ph7_3 GO:0018405 biolink:BiologicalProcess protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues. RESID:AA0247 go-plus.json protein-keratan sulphate linkage via keratan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine http://purl.obolibrary.org/obo/GO_0018405 GO:0018404 biolink:BiologicalProcess protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues. RESID:AA0210 go-plus.json protein-heparan sulphate linkage via heparan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine http://purl.obolibrary.org/obo/GO_0018404 CHEBI:58659 biolink:ChemicalSubstance 8(R)-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58659 chebi_ph7_3 UBERON:0005637 biolink:AnatomicalEntity pyloric region epithelium An epithelium that is part of a pylorus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005637 UBERON:0005636 biolink:AnatomicalEntity caecum epithelium An epithelium that is part of a caecum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005636 CHEBI:58658 biolink:ChemicalSubstance alpha-D-galacturonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58658 chebi_ph7_3 GO:0018401 biolink:BiologicalProcess peptidyl-proline hydroxylation to 4-hydroxy-L-proline The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase. RESID:AA0030 go-plus.json http://purl.obolibrary.org/obo/GO_0018401 GO:0018400 biolink:BiologicalProcess peptidyl-proline hydroxylation to 3-hydroxy-L-proline The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase. RESID:AA0029 go-plus.json http://purl.obolibrary.org/obo/GO_0018400 CHEBI:58655 biolink:ChemicalSubstance (S)-3-aminoisobutyric acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58655 chebi_ph7_3 UBERON:0005631 biolink:AnatomicalEntity extraembryonic membrane Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005631 CHEBI:58652 biolink:ChemicalSubstance N(omega)-phosphohypotaurocyamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58652 chebi_ph7_3 CHEBI:20056 biolink:ChemicalSubstance 3-hydroxy-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_20056 UBERON:0005619 biolink:AnatomicalEntity secondary palatal shelf The outgrowths of the embryonic maxillary prominences that come together during prenatal development to form the secondary palate go-plus.json lateral palatine process|palatal shelf|palatal shelves|palatine shelf|secondary palatal shelf http://purl.obolibrary.org/obo/UBERON_0005619 UBERON:0005617 biolink:AnatomicalEntity mesenteric vein A vein that returns blood from the intestines. go-plus.json intestinal vein http://purl.obolibrary.org/obo/UBERON_0005617 UBERON:0005616 biolink:AnatomicalEntity mesenteric artery Arteries which arise from the abdominal aorta and distribute to most of the intestines. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005616 CHEBI:58640 biolink:ChemicalSubstance pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58640 chebi_ph7_3 GO:0018418 biolink:BiologicalProcess nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide. RESID:AA0 go-plus.json nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide http://purl.obolibrary.org/obo/GO_0018418 GO:0018417 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide. RESID:AA0293 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide http://purl.obolibrary.org/obo/GO_0018417 GO:0018419 biolink:BiologicalProcess protein catenane formation The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain. go-plus.json http://purl.obolibrary.org/obo/GO_0018419 GO:0018414 biolink:BiologicalProcess nickel incorporation into metallo-sulfur cluster The incorporation of nickel into a metallo-sulfur cluster. go-plus.json nickel incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0018414 GO:0018413 biolink:BiologicalProcess peptidyl-serine O-glucuronidation The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine. RESID:AA0291 go-plus.json http://purl.obolibrary.org/obo/GO_0018413 GO:0018416 biolink:BiologicalProcess nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide. RESID:AA0292 go-plus.json nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide http://purl.obolibrary.org/obo/GO_0018416 GO:0018415 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide. RESID:AA0292 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide http://purl.obolibrary.org/obo/GO_0018415 UBERON:0005626 biolink:AnatomicalEntity ventral mesogastrium Portion of ventral mesentery closest to the stomach. go-plus.json foregut ventral mesentery http://purl.obolibrary.org/obo/UBERON_0005626 GO:0018410 biolink:BiologicalProcess C-terminal protein amino acid modification The alteration of the C-terminal amino acid residue in a protein. go-plus.json peptide/protein carboxyl-terminal blocking|peptide or protein carboxyl-terminal blocking http://purl.obolibrary.org/obo/GO_0018410 UBERON:0005625 biolink:AnatomicalEntity tubotympanic recess lumen The cavity formed by the tubotympanic recess epithelium. go-plus.json tubotympanic recess|tubotympanic recess space|tubotympanic recess cavity|cavity of tubotympanic recess http://purl.obolibrary.org/obo/UBERON_0005625 CHEBI:58647 biolink:ChemicalSubstance amidinoproclavaminic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58647 chebi_ph7_3 GO:0018412 biolink:BiologicalProcess protein O-glucuronidation The modification of a protein by glucuronidation on an amino acid oxygen atom. go-plus.json protein amino acid O-glucuronidation http://purl.obolibrary.org/obo/GO_0018412 UBERON:0005624 biolink:AnatomicalEntity suprarenal artery Artery that supplies blood to the adrenal glands. go-plus.json adrenal artery http://purl.obolibrary.org/obo/UBERON_0005624 GO:0018411 biolink:BiologicalProcess protein glucuronidation The modification of a protein by amino acid glucuronidation. go-plus.json protein amino acid glucuronidation http://purl.obolibrary.org/obo/GO_0018411 CHEBI:58645 biolink:ChemicalSubstance D-allothreonine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58645 chebi_ph7_3 UBERON:0005623 biolink:AnatomicalEntity semi-lunar valve the valves that gate the flow of blood from the ventricles into the aorta and pulmonary trunk go-plus.json semilunar valves|semilunar valve http://purl.obolibrary.org/obo/UBERON_0005623 UBERON:0005622 biolink:AnatomicalEntity right dorsal aorta go-plus.json http://purl.obolibrary.org/obo/UBERON_0005622 CHEBI:58644 biolink:ChemicalSubstance p-coumaroylagmatine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58644 chebi_ph7_3 UBERON:0005620 biolink:AnatomicalEntity primary palate The part of the palate formed from the intermaxillary segment. go-plus.json primary palate|palatum primarium|primitive palate|processus palatinus medianus|primary palate process http://purl.obolibrary.org/obo/UBERON_0005620 CHEBI:58642 biolink:ChemicalSubstance 2,3-dihydroxy-trans-cinnamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58642 chebi_ph7_3 CHEBI:58641 biolink:ChemicalSubstance N,N-dimethylethanolamine phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58641 chebi_ph7_3 UBERON:0005609 biolink:AnatomicalEntity iliac artery Any of the arteries that arise from a bifurcation of the aorta supplying the pelvic or abdomen. Examples: Common iliac artery, External iliac artery, Internal iliac artery go-plus.json http://purl.obolibrary.org/obo/UBERON_0005609 UBERON:0005607 biolink:AnatomicalEntity hyaloid vascular plexus go-plus.json hyaloid vascular system http://purl.obolibrary.org/obo/UBERON_0005607 CHEBI:58639 biolink:ChemicalSubstance 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58639 chebi_ph7_3 NCBITaxon:7227 biolink:OrganismalEntity Drosophila melanogaster go-plus.json fruit fly|Sophophora melanogaster http://purl.obolibrary.org/obo/NCBITaxon_7227 UBERON:0005606 biolink:AnatomicalEntity hyaloid cavity go-plus.json http://purl.obolibrary.org/obo/UBERON_0005606 CHEBI:58638 biolink:ChemicalSubstance 4'''-demalonylsalvianin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58638 chebi_ph7_3 CHEBI:58637 biolink:ChemicalSubstance 2-hydroxy-6-oxonona-2,4,7-trienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58637 chebi_ph7_3 UBERON:0005614 biolink:AnatomicalEntity lens anterior epithelium A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex. go-plus.json anterior surface of lens|lens subcapsular epithelium|lens epithelium|subcapsular lens epithelium|anterior epithelium of lens vesicle http://purl.obolibrary.org/obo/UBERON_0005614 CHEBI:58636 biolink:ChemicalSubstance 2-hydroxy-2,3-dihydrogenistein-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58636 CHEBI:58635 biolink:ChemicalSubstance 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58635 chebi_ph7_3 UBERON:0005613 biolink:AnatomicalEntity left dorsal aorta go-plus.json http://purl.obolibrary.org/obo/UBERON_0005613 CHEBI:58633 biolink:ChemicalSubstance L-homoserine lactone(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58633 chebi_ph7_3 CHEBI:58632 biolink:ChemicalSubstance 2,4-divinyl protochlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58632 chebi_ph7_3 UBERON:0005610 biolink:AnatomicalEntity iliac vein Any of the three veins including the common, external and internal iliac veins. go-plus.json pelvic vein http://purl.obolibrary.org/obo/UBERON_0005610 CHEBI:58630 biolink:ChemicalSubstance N-methylanthraniloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58630 chebi_ph7_3 CHEBI:19062 biolink:ChemicalSubstance 1-methylguanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_19062 chebi_ph7_3 CHEBI:58629 biolink:ChemicalSubstance N-formyl-L-kynurenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58629 chebi_ph7_3 CHEBI:58628 biolink:ChemicalSubstance 5-diphospho-1D-myo-inositol pentakisphosphate(13-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58628 chebi_ph7_3 CHEBI:58627 biolink:ChemicalSubstance gibberellin A12(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58627 chebi_ph7_3 UBERON:0005604 biolink:AnatomicalEntity extrahepatic part of hepatic duct go-plus.json hepatic duct extrahepatic part|extrahepatic part of the hepatic duct http://purl.obolibrary.org/obo/UBERON_0005604 UBERON:0005602 biolink:AnatomicalEntity dorsal mesogastrium The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum. go-plus.json dorsal mesentery http://purl.obolibrary.org/obo/UBERON_0005602 CHEBI:58622 biolink:ChemicalSubstance 5alpha,9beta,10alpha-labda-8(20),13-dien-15-yl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58622 chebi_ph7_3 CHEBI:58621 biolink:ChemicalSubstance dehydroabietate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58621 chebi_ph7_3 CHEBI:58619 biolink:ChemicalSubstance S-alkyl thiosulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58619 chebi_ph7_3 CHEBI:58618 biolink:ChemicalSubstance hydrogenselenophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58618 CHEBI:58616 biolink:ChemicalSubstance 2-methyl-4-oxo-1,4-dihydroquinolin-3-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58616 UBERON:0005673 biolink:AnatomicalEntity left lung endothelium An endothelium that is part of a left lung. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005673 UBERON:0005672 biolink:AnatomicalEntity right lung endothelium An endothelium that is part of a right lung. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005672 CHEBI:58614 biolink:ChemicalSubstance 2,5-diamino-4-hydroxy-6-(5-phosphonatoribosylamino)pyrimidine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58614 chebi_ph7_3 CHEBI:58613 biolink:ChemicalSubstance 1-(2-carboxylatophenylamino)-1-deoxy-D-ribulose 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58613 chebi_ph7_3 CHEBI:58612 biolink:ChemicalSubstance (+-)-5-[3-(tert-butylammonio)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58612 chebi_ph7_3 CHEBI:58611 biolink:ChemicalSubstance (+-)-5-[3-(tert-butylammonio)-2-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58611 chebi_ph7_3 UBERON:0005677 biolink:AnatomicalEntity caecum mesentery A mesentery that is part of a caecum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005677 CHEBI:58610 biolink:ChemicalSubstance nocardicin E(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58610 CHEBI:20012 biolink:ChemicalSubstance 3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_20012 CHEBI:58609 biolink:ChemicalSubstance D-2-ammoniohexano-6-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_58609 chebi_ph7_3 CHEBI:58608 biolink:ChemicalSubstance 1,2-diacyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58608 chebi_ph7_3 CHEBI:58607 biolink:ChemicalSubstance 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58607 chebi_ph7_3 CHEBI:20013 biolink:ChemicalSubstance 3-epi-3-hydroxymugineic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20013 CHEBI:58606 biolink:ChemicalSubstance synephrinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58606 chebi_ph7_3 CHEBI:20016 biolink:ChemicalSubstance 3-ethylcatechols go-plus.json http://purl.obolibrary.org/obo/CHEBI_20016 CHEBI:58605 biolink:ChemicalSubstance 3''-adenylylstreptomycin(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58605 chebi_ph7_3 CHEBI:10668 biolink:ChemicalSubstance tRNA precursor go-plus.json http://purl.obolibrary.org/obo/CHEBI_10668 UBERON:0005662 biolink:AnatomicalEntity 4th arch ectoderm An ectoderm that is part of a pharyngeal arch 4. go-plus.json 4th pharyngeal arch ectoderm http://purl.obolibrary.org/obo/UBERON_0005662 CHEBI:2024 biolink:ChemicalSubstance 5-acetamidopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2024 UBERON:0005661 biolink:AnatomicalEntity 3rd arch ectoderm An ectoderm that is part of a pharyngeal arch 3. go-plus.json 3rd pharyngeal arch ectoderm http://purl.obolibrary.org/obo/UBERON_0005661 UBERON:0005660 biolink:AnatomicalEntity 2nd arch ectoderm An ectoderm that is part of a pharyngeal arch 2. go-plus.json 2nd pharyngeal arch ectoderm http://purl.obolibrary.org/obo/UBERON_0005660 CHEBI:58604 biolink:ChemicalSubstance L-mimosine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58604 UBERON:0005669 biolink:AnatomicalEntity peritoneal cavity mesothelium A mesothelium that is part of a peritoneal cavity. go-plus.json mesothelium of peritoneum|peritoneum|peritoneum mesothelium|mesothelium of peritoneal component|peritoneal mesothelium http://purl.obolibrary.org/obo/UBERON_0005669 CHEBI:58603 biolink:ChemicalSubstance lipid IVA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58603 chebi_ph7_3 CHEBI:58602 biolink:ChemicalSubstance D-mannosyl undecaprenyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58602 chebi_ph7_3 CHEBI:58601 biolink:ChemicalSubstance alpha-D-glucose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58601 chebi_ph7_3 UBERON:0005667 biolink:AnatomicalEntity connecting stalk mesoderm go-plus.json http://purl.obolibrary.org/obo/UBERON_0005667 CHEBI:58600 biolink:ChemicalSubstance N(tele)-methylhistaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58600 chebi_ph7_3 UBERON:0005666 biolink:AnatomicalEntity 4th arch endoderm An endoderm that is part of a pharyngeal arch 4. go-plus.json 4th pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0005666 UBERON:0005665 biolink:AnatomicalEntity 3rd arch endoderm An endoderm that is part of a pharyngeal arch 3. go-plus.json 3rd pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0005665 UBERON:0005664 biolink:AnatomicalEntity 2nd arch endoderm An endoderm that is part of a pharyngeal arch 2. go-plus.json 2nd pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0005664 CHEBI:19030 biolink:ChemicalSubstance 1-aminopropan-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_19030 CHEBI:10698 biolink:ChemicalSubstance 2-cis,6-trans,10-trans-geranylgeranyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_10698 CHEBI:10696 biolink:ChemicalSubstance (3S)-3-hydroxy-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_10696 CHEBI:19029 biolink:ChemicalSubstance 1-aminopropan-2-yl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19029 UBERON:0005659 biolink:AnatomicalEntity primary palate epithelium An epithelium that is part of a primary palate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005659 UBERON:0005658 biolink:AnatomicalEntity secondary palatal shelf epithelium An epithelium that is part of a secondary palatal shelf. go-plus.json palatal shelf epithelium http://purl.obolibrary.org/obo/UBERON_0005658 UBERON:0005656 biolink:AnatomicalEntity lens vesicle epithelium An epithelium that is part of a lens vesicle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005656 UBERON:0005638 biolink:AnatomicalEntity anterior chamber epithelium An epithelium that is part of a anterior chamber of eyeball. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005638 CHEBI:2003 biolink:ChemicalSubstance 5,6-dihydroxyindole-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2003 OBO:GOCHE_35473 biolink:OntologyClass substance with tranquilizing drug role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35473 3_STAR OBO:GOCHE_35471 biolink:OntologyClass substance with psychotropic drug role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35471 3_STAR OBO:GOCHE_35470 biolink:OntologyClass substance with central nervous system drug role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35470 3_STAR GO:0043575 biolink:BiologicalProcess detection of osmotic stimulus The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0043575 GO:0043574 biolink:BiologicalProcess peroxisomal transport Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0043574 OBO:GOCHE_35476 biolink:OntologyClass substance with antipsychotic agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35476 3_STAR GO:0043577 biolink:BiologicalProcess chemotropism The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it. Wikipedia:Chemotropism go-plus.json http://purl.obolibrary.org/obo/GO_0043577 GO:0043576 biolink:BiologicalProcess regulation of respiratory gaseous exchange Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0043576 GO:0043571 biolink:BiologicalProcess maintenance of CRISPR repeat elements Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences. go-plus.json maintenance of clustered regularly interspaced short palindromic repeat elements|CRISPR element metabolic process|CRISPR element metabolism http://purl.obolibrary.org/obo/GO_0043571 GO:0043570 biolink:BiologicalProcess maintenance of DNA repeat elements Any process involved in sustaining the fidelity and copy number of DNA repeat elements. go-plus.json http://purl.obolibrary.org/obo/GO_0043570 GO:0043573 biolink:BiologicalProcess leucoplast fission The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes. go-plus.json http://purl.obolibrary.org/obo/GO_0043573 GO:0043572 biolink:BiologicalProcess plastid fission The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0043572 GO:0043579 biolink:BiologicalProcess elaioplast organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored. go-plus.json elaioplast organization and biogenesis|elaioplast organisation http://purl.obolibrary.org/obo/GO_0043579 GO:0043578 biolink:BiologicalProcess nuclear matrix organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane. go-plus.json nuclear matrix organization and biogenesis|nuclear matrix organisation|nucleoskeleton organization http://purl.obolibrary.org/obo/GO_0043578 GO:0043580 biolink:BiologicalProcess periplasmic space organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi. go-plus.json periplasmic space organization and biogenesis|periplasmic space organisation http://purl.obolibrary.org/obo/GO_0043580 GO:0043586 biolink:BiologicalProcess tongue development The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. go-plus.json glossa development|lingua development http://purl.obolibrary.org/obo/GO_0043586 OBO:GOCHE_35488 biolink:OntologyClass substance with central nervous system depressant role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35488 3_STAR GO:0043585 biolink:BiologicalProcess nose morphogenesis The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). go-plus.json nasus morphogenesis http://purl.obolibrary.org/obo/GO_0043585 GO:0043588 biolink:BiologicalProcess skin development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. go-plus.json animal skin development http://purl.obolibrary.org/obo/GO_0043588 GO:0102400 biolink:MolecularActivity dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+. MetaCyc:RXN-13667 go-plus.json http://purl.obolibrary.org/obo/GO_0102400 GO:0043587 biolink:BiologicalProcess tongue morphogenesis The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. go-plus.json lingua morphogenesis|glossa morphogenesis http://purl.obolibrary.org/obo/GO_0043587 GO:0043582 biolink:BiologicalProcess sporangium development The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores. go-plus.json sporangia development http://purl.obolibrary.org/obo/GO_0043582 GO:0102402 biolink:MolecularActivity 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose. EC:3.2.1.149|MetaCyc:RXN-13694 go-plus.json http://purl.obolibrary.org/obo/GO_0102402 GO:0043581 biolink:BiologicalProcess obsolete mycelium development OBSOLETE. The process whose specific outcome is the progression of the mycelium over time, from its formation to the mature structure. A mycelium consists of a mass of branching, thread-like hyphae. go-plus.json http://purl.obolibrary.org/obo/GO_0043581 GO:0043584 biolink:BiologicalProcess nose development The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). go-plus.json nasus development http://purl.obolibrary.org/obo/GO_0043584 GO:0102405 biolink:MolecularActivity (+)-taxifolin 5'-hydroxylase activity Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O. MetaCyc:RXN-13718|RHEA:61116 go-plus.json http://purl.obolibrary.org/obo/GO_0102405 GO:0102404 biolink:MolecularActivity linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool. EC:3.2.1.149|MetaCyc:RXN-13701 go-plus.json http://purl.obolibrary.org/obo/GO_0102404 GO:0043583 biolink:BiologicalProcess ear development The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. go-plus.json hearing organ development http://purl.obolibrary.org/obo/GO_0043583 GO:0102407 biolink:MolecularActivity sn-2-glycerol-3-phosphate C22:0-DCA-CoA acyl transferase activity Catalysis of the reaction: C22:0-DCA-CoA + sn-glycerol 3-phosphate <=> coenzyme A + 2-C22:0-DCA-LPA. MetaCyc:RXN-13734 go-plus.json http://purl.obolibrary.org/obo/GO_0102407 GO:0102406 biolink:MolecularActivity omega-hydroxypalmitate O-sinapoyl transferase activity Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate. MetaCyc:RXN-13728|EC:2.3.1.188|RHEA:26470 go-plus.json http://purl.obolibrary.org/obo/GO_0102406 GO:0102409 biolink:MolecularActivity sn-2-glycerol-3-phosphate C16:0-CoA acyl transferase activity Catalysis of the reaction: behenoyl-CoA + sn-glycerol 3-phosphate(2-) <=> coenzyme A + 2-docosanoyl-glycerol 3-phosphate. MetaCyc:RXN-13736 go-plus.json http://purl.obolibrary.org/obo/GO_0102409 GO:0102408 biolink:MolecularActivity sn-2-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate <=> coenzyme A + sn-2-C16:0-DCA-LPA. MetaCyc:RXN-13735 go-plus.json http://purl.obolibrary.org/obo/GO_0102408 GO:0043589 biolink:BiologicalProcess skin morphogenesis The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0043589 GO:0043591 biolink:CellularComponent endospore external encapsulating structure The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer. go-plus.json peptidoglycan-based spore wall|endospore wall|spore wall http://purl.obolibrary.org/obo/GO_0043591 goslim_pir GO:0018591 biolink:MolecularActivity methyl tertiary butyl ether 3-monooxygenase activity Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde. go-plus.json MTBE 3-monooxygenase activity http://purl.obolibrary.org/obo/GO_0018591 GO:0043590 biolink:CellularComponent bacterial nucleoid The region of a bacterial cell to which the DNA is confined. go-plus.json http://purl.obolibrary.org/obo/GO_0043590 GO:0018590 biolink:MolecularActivity methylsilanetriol hydroxylase activity Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol. UM-BBD_reactionID:r0640 go-plus.json http://purl.obolibrary.org/obo/GO_0018590 GO:0043597 biolink:CellularComponent cytoplasmic replication fork The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0043597 GO:0102410 biolink:MolecularActivity quercetin-4',3-O-glucosyltransferase activity Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-). MetaCyc:RXN-13765 go-plus.json http://purl.obolibrary.org/obo/GO_0102410 GO:0043596 biolink:CellularComponent nuclear replication fork The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0043596 OBO:GOCHE_35498 biolink:OntologyClass substance with diuretic role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35498 3_STAR GO:0043599 biolink:CellularComponent nuclear DNA replication factor C complex A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species. go-plus.json nuclear RFC http://purl.obolibrary.org/obo/GO_0043599 GO:0102412 biolink:MolecularActivity valerena-4,7(11)-diene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid. RHEA:34467|EC:4.2.3.139|MetaCyc:RXN-13769 go-plus.json http://purl.obolibrary.org/obo/GO_0102412 GO:0043598 biolink:CellularComponent cytoplasmic DNA replication factor C complex A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species. go-plus.json cytoplasmic RFC|cytoplasmic clamp loader http://purl.obolibrary.org/obo/GO_0043598 GO:0102411 biolink:MolecularActivity quercetin-3,4'-O-glucosyltransferase activity Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-). MetaCyc:RXN-13766 go-plus.json http://purl.obolibrary.org/obo/GO_0102411 GO:0043593 biolink:CellularComponent endospore coat The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination. go-plus.json http://purl.obolibrary.org/obo/GO_0043593 GO:0102414 biolink:MolecularActivity quercetin-3-O-glucoside 1,6-glucosyltransferase activity Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP. MetaCyc:RXN-13797 go-plus.json http://purl.obolibrary.org/obo/GO_0102414 GO:0043592 biolink:CellularComponent exosporium The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid. go-plus.json exospore|epispore|perispore http://purl.obolibrary.org/obo/GO_0043592 GO:0102413 biolink:MolecularActivity 6-O-methyl-deacetylisoipecoside beta-glucosidase activity Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose. MetaCyc:RXN-13791 go-plus.json http://purl.obolibrary.org/obo/GO_0102413 GO:0043595 biolink:CellularComponent endospore cortex A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0043595 GO:0102416 biolink:MolecularActivity quercetin gentiotrioside 1,6-glucosyltransferase activity Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+. MetaCyc:RXN-13799 go-plus.json http://purl.obolibrary.org/obo/GO_0102416 GO:0043594 biolink:CellularComponent outer endospore membrane The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat. go-plus.json http://purl.obolibrary.org/obo/GO_0043594 GO:0102415 biolink:MolecularActivity quercetin gentiobioside 1,6-glucosyltransferase activity Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+. MetaCyc:RXN-13798 go-plus.json http://purl.obolibrary.org/obo/GO_0102415 GO:0102418 biolink:MolecularActivity luteolin-7-O-glucoside 1,6-glucosyltransferase activity Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+. MetaCyc:RXN-13801 go-plus.json http://purl.obolibrary.org/obo/GO_0102418 GO:0102417 biolink:MolecularActivity apigenin-7-O-glucoside 1,6-glucosyltransferase activity Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+. MetaCyc:RXN-13800 go-plus.json http://purl.obolibrary.org/obo/GO_0102417 GO:0102419 biolink:MolecularActivity sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity Catalysis of the reaction: omega-hydroxy-C22:0-CoA + sn-glycerol 3-phosphate = coenzyme A + 2-omega-hydroxy-C22:0-LPA. RHEA:33559|MetaCyc:RXN-13803|EC:2.3.1.198 go-plus.json http://purl.obolibrary.org/obo/GO_0102419 GO:0018589 biolink:MolecularActivity di-n-butyltin dioxygenase activity Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin. UM-BBD_reactionID:r0645 go-plus.json DBT dioxygenase activity http://purl.obolibrary.org/obo/GO_0018589 NCBITaxon:102814 biolink:OrganismalEntity Heliantheae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_102814 GO:0018586 biolink:MolecularActivity mono-butyltin dioxygenase activity Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin. UM-BBD_reactionID:r0647 go-plus.json MBT dioxygenase activity http://purl.obolibrary.org/obo/GO_0018586 GO:0018585 biolink:MolecularActivity fluorene oxygenase activity Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol. UM-BBD_reactionID:r0407 go-plus.json http://purl.obolibrary.org/obo/GO_0018585 GO:0018588 biolink:MolecularActivity tri-n-butyltin dioxygenase activity Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin. UM-BBD_reactionID:r0643 go-plus.json TBT dioxygenase activity http://purl.obolibrary.org/obo/GO_0018588 GO:0018587 biolink:MolecularActivity obsolete limonene 8-monooxygenase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json limonene 8-monooxygenase activity http://purl.obolibrary.org/obo/GO_0018587 GO:0018582 biolink:MolecularActivity 1-hydroxy-2-naphthoate 1,2-dioxygenase activity Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate. MetaCyc:1.13.11.38-RXN|RHEA:14749|UM-BBD_reactionID:r0486|EC:1.13.11.38 go-plus.json 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)|1-hydroxy-2-naphthoate dioxygenase activity|1-hydroxy-2-naphthoic acid dioxygenase activity|1-hydroxy-2-naphthoate-degrading enzyme activity http://purl.obolibrary.org/obo/GO_0018582 GO:0018581 biolink:MolecularActivity hydroxyquinol 1,2-dioxygenase activity Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate. UM-BBD_reactionID:r0232|MetaCyc:HYDROXYQUINOL-12-DIOXYGENASE-RXN|RHEA:19441|EC:1.13.11.37 go-plus.json hydroxyquinol dioxygenase activity|benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0018581 GO:0018584 biolink:MolecularActivity 2,4,5-trichlorophenoxyacetic acid oxygenase activity Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol. EC:1.13.99.-|UM-BBD_reactionID:r0359 go-plus.json http://purl.obolibrary.org/obo/GO_0018584 GO:0018583 biolink:MolecularActivity biphenyl-2,3-diol 1,2-dioxygenase activity Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O. RHEA:14413|EC:1.13.11.39|MetaCyc:BIPHENYL-23-DIOL-12-DIOXYGENASE-RXN|UM-BBD_enzymeID:e0127 go-plus.json biphenyl-2,3-diol dioxygenase activity|biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)|2,3-dihydroxybiphenyl 1,2-dioxygenase activity|2,3-dihydroxybiphenyl dioxygenase activity http://purl.obolibrary.org/obo/GO_0018583 GO:0102421 biolink:MolecularActivity curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+. MetaCyc:RXN-13813 go-plus.json http://purl.obolibrary.org/obo/GO_0102421 GO:0102420 biolink:MolecularActivity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate. MetaCyc:RXN-13805|EC:2.3.1.15 go-plus.json http://purl.obolibrary.org/obo/GO_0102420 GO:0102423 biolink:MolecularActivity (+)-sesaminol 2-O-glucosyltransferase activity Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+. MetaCyc:RXN-13818 go-plus.json http://purl.obolibrary.org/obo/GO_0102423 GO:0102422 biolink:MolecularActivity curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+. MetaCyc:RXN-13814 go-plus.json http://purl.obolibrary.org/obo/GO_0102422 GO:0102425 biolink:MolecularActivity myricetin 3-O-glucosyltransferase activity Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP. EC:2.4.1.91|MetaCyc:RXN-13822 go-plus.json http://purl.obolibrary.org/obo/GO_0102425 GO:0102424 biolink:MolecularActivity sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+. MetaCyc:RXN-13821 go-plus.json http://purl.obolibrary.org/obo/GO_0102424 GO:0102427 biolink:MolecularActivity allocryptopine 6-hydroxylase activity Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O. MetaCyc:RXN-13828 go-plus.json http://purl.obolibrary.org/obo/GO_0102427 GO:0102426 biolink:MolecularActivity myricetin-3-O-glucoside 1,6-glucosyltransferase activity Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+. MetaCyc:RXN-13823 go-plus.json http://purl.obolibrary.org/obo/GO_0102426 GO:0102429 biolink:MolecularActivity genistein-3-O-glucoside 1,6-glucosyltransferase activity Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+. MetaCyc:RXN-13831 go-plus.json http://purl.obolibrary.org/obo/GO_0102429 GO:0102428 biolink:MolecularActivity kaempferol-3-O-glucoside 1,6-glucosyltransferase activity Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP. MetaCyc:RXN-13830 go-plus.json http://purl.obolibrary.org/obo/GO_0102428 NCBITaxon:102804 biolink:OrganismalEntity Asteroideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_102804 GO:0018597 biolink:MolecularActivity ammonia monooxygenase activity Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions. EC:1.14.99.39|UM-BBD_enzymeID:e0061|RHEA:27341 go-plus.json http://purl.obolibrary.org/obo/GO_0018597 GO:0018596 biolink:MolecularActivity dimethylsilanediol hydroxylase activity Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol. UM-BBD_reactionID:r0637 go-plus.json DMSD hydroxylase activity http://purl.obolibrary.org/obo/GO_0018596 GO:0018599 biolink:MolecularActivity 2-hydroxyisobutyrate 3-monooxygenase activity Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate. UM-BBD_reactionID:r0619 go-plus.json http://purl.obolibrary.org/obo/GO_0018599 GO:0018598 biolink:MolecularActivity hydroxymethylsilanetriol oxidase activity Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol. UM-BBD_reactionID:r0641 go-plus.json http://purl.obolibrary.org/obo/GO_0018598 GO:0018593 biolink:MolecularActivity 4-chlorophenoxyacetate monooxygenase activity Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol. UM-BBD_reactionID:r0281 go-plus.json http://purl.obolibrary.org/obo/GO_0018593 GO:0018592 biolink:MolecularActivity 4-nitrocatechol 4-monooxygenase activity Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol. EC:1.14.13.166|UM-BBD_reactionID:r0231 go-plus.json http://purl.obolibrary.org/obo/GO_0018592 GO:0018595 biolink:MolecularActivity alpha-pinene monooxygenase activity Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol. UM-BBD_reactionID:r0716|EC:1.14.13.155|RHEA:32891 go-plus.json http://purl.obolibrary.org/obo/GO_0018595 GO:0018594 biolink:MolecularActivity tert-butanol 2-monooxygenase activity Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol. go-plus.json tert-butyl alcohol 2-monooxygenase activity http://purl.obolibrary.org/obo/GO_0018594 GO:0018568 biolink:MolecularActivity 3,4-dihydroxyphenanthrene dioxygenase activity Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate. UM-BBD_reactionID:r0501|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018568 GO:0018567 biolink:MolecularActivity styrene dioxygenase activity Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol. EC:1.13.11.-|UM-BBD_reactionID:r0256 go-plus.json http://purl.obolibrary.org/obo/GO_0018567 GO:0018569 biolink:MolecularActivity hydroquinone 1,2-dioxygenase activity Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde. UM-BBD_reactionID:r0228|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018569 GO:0018564 biolink:MolecularActivity carbazole 1,9a-dioxygenase activity Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol. EC:1.13.11.-|UM-BBD_reactionID:r0456 go-plus.json carbazole 1,9alpha-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018564 GO:0018563 biolink:MolecularActivity 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate. EC:1.13.11.-|UM-BBD_reactionID:r0310 go-plus.json http://purl.obolibrary.org/obo/GO_0018563 GO:0018566 biolink:MolecularActivity 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate. EC:1.13.11.-|UM-BBD_reactionID:r0324 go-plus.json 1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018566 GO:0018565 biolink:MolecularActivity dihydroxydibenzothiophene dioxygenase activity Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate. EC:1.13.11.-|UM-BBD_reactionID:r0162 go-plus.json http://purl.obolibrary.org/obo/GO_0018565 GO:0018560 biolink:MolecularActivity protocatechuate 3,4-dioxygenase type II activity Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate. EC:1.13.11.-|UM-BBD_reactionID:r0581 go-plus.json http://purl.obolibrary.org/obo/GO_0018560 GO:0018562 biolink:MolecularActivity 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid. UM-BBD_reactionID:r0415|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018562 GO:0018561 biolink:MolecularActivity 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate. EC:1.13.11.-|UM-BBD_reactionID:r0457 go-plus.json http://purl.obolibrary.org/obo/GO_0018561 GO:0018580 biolink:MolecularActivity nitronate monooxygenase activity Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite. RHEA:28767|MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN|EC:1.13.12.16 go-plus.json 2-nitropropane dioxygenase activity|nitronate:oxygen 2-oxidoreductase (nitrite-forming) activity http://purl.obolibrary.org/obo/GO_0018580 GO:0018579 biolink:MolecularActivity protocatechuate 4,5-dioxygenase activity Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde. RHEA:24044|MetaCyc:PROTOCATECHUATE-45-DIOXYGENASE-RXN|EC:1.13.11.8|UM-BBD_reactionID:r0144 go-plus.json protocatechuate 4,5-oxygenase activity|protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)|protocatechuic 4,5-dioxygenase activity|protocatechuic 4,5-oxygenase activity http://purl.obolibrary.org/obo/GO_0018579 GO:0018578 biolink:MolecularActivity protocatechuate 3,4-dioxygenase activity Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate. RHEA:10084|MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN|EC:1.13.11.3|UM-BBD_reactionID:r0143 go-plus.json protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)|protocatechuic 3,4-dioxygenase activity|protocatechuate oxygenase activity|protocatechuic 3,4-oxygenase activity|protocatechuic acid oxidase activity http://purl.obolibrary.org/obo/GO_0018578 GO:0018575 biolink:MolecularActivity chlorocatechol 1,2-dioxygenase activity Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate. UM-BBD_reactionID:r0655|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018575 GO:0018574 biolink:MolecularActivity 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate. UM-BBD_enzymeID:e0422|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018574 GO:0018577 biolink:MolecularActivity catechol 2,3-dioxygenase activity Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde. UM-BBD_enzymeID:e0156|EC:1.13.11.2|RHEA:17337|MetaCyc:CATECHOL-23-DIOXYGENASE-RXN go-plus.json pyrocatechol 2,3-dioxygenase|catechol 2,3-oxygenase|2,3-pyrocatechase activity|catechol oxygenase|catechol:oxygen 2,3-oxidoreductase (decyclizing)|metapyrocatechase activity|cato2ase activity http://purl.obolibrary.org/obo/GO_0018577 GO:0018576 biolink:MolecularActivity catechol 1,2-dioxygenase activity Catalysis of the reaction: catechol + O2 = cis,cis-muconate. EC:1.13.11.1|UM-BBD_enzymeID:e0064|RHEA:23852|MetaCyc:CATECHOL-12-DIOXYGENASE-RXN go-plus.json catechol:oxygen 1,2-oxidoreductase activity|1,2-pyrocatechase activity|CD I|catechol-oxygen 1,2-oxidoreductase activity|catechol 1,2-oxygenase activity|pyrocatechol 1,2-dioxygenase activity|CD II|pyrocatechase activity|catechase activity http://purl.obolibrary.org/obo/GO_0018576 GO:0018571 biolink:MolecularActivity 2,3-dihydroxy-p-cumate dioxygenase activity Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate. MetaCyc:RXN-666|RHEA:42568|UM-BBD_reactionID:r0397 go-plus.json 2,3-dihydroxy-p-cumate-3,4-dioxygenase|2,3-dihydroxy-p-cumate 3,4-dioxygenase http://purl.obolibrary.org/obo/GO_0018571 GO:0018570 biolink:MolecularActivity p-cumate 2,3-dioxygenase activity Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate. EC:1.14.12.25|MetaCyc:RXN-664|RHEA:42344|UM-BBD_reactionID:r0395 go-plus.json http://purl.obolibrary.org/obo/GO_0018570 GO:0018573 biolink:MolecularActivity 2-aminophenol 1,6-dioxygenase activity Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde. UM-BBD_reactionID:r0305|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018573 GO:0018572 biolink:MolecularActivity 3,5-dichlorocatechol 1,2-dioxygenase activity Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate. EC:1.13.11.-|UM-BBD_reactionID:r0276 go-plus.json http://purl.obolibrary.org/obo/GO_0018572 GO:0018549 biolink:MolecularActivity methanethiol oxidase activity Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide. UM-BBD_reactionID:r0209|MetaCyc:METHANETHIOL-OXIDASE-RXN|RHEA:11812|EC:1.8.3.4 go-plus.json methyl mercaptan oxidase activity|methylmercaptan oxidase activity|methanethiol:oxygen oxidoreductase activity|(MM)-oxidase activity|MT-oxidase activity http://purl.obolibrary.org/obo/GO_0018549 CHEBI:138888 biolink:ChemicalSubstance (R)-3-hydroxy-4-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138888 GO:0018546 biolink:MolecularActivity nitrobenzene nitroreductase activity Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O. MetaCyc:RXN-8815|UM-BBD_enzymeID:e0245|RHEA:52884 go-plus.json http://purl.obolibrary.org/obo/GO_0018546 GO:0018545 biolink:MolecularActivity NAD(P)H nitroreductase activity Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative. UM-BBD_enzymeID:e0346 go-plus.json http://purl.obolibrary.org/obo/GO_0018545 GO:0018548 biolink:MolecularActivity pentaerythritol trinitrate reductase activity Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate. EC:1.6.99.1|UM-BBD_reactionID:r0025 go-plus.json xenobiotic reductase activity http://purl.obolibrary.org/obo/GO_0018548 GO:0018547 biolink:MolecularActivity nitroglycerin reductase activity Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative. UM-BBD_enzymeID:e0038 go-plus.json NG reductase activity http://purl.obolibrary.org/obo/GO_0018547 GO:0018542 biolink:MolecularActivity 2,3-dihydroxy DDT 1,2-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate. EC:1.13.11.-|UM-BBD_reactionID:r0452 go-plus.json http://purl.obolibrary.org/obo/GO_0018542 CHEBI:138881 biolink:ChemicalSubstance beta-D-fructofuranose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138881 chebi_ph7_3 GO:0018541 biolink:MolecularActivity p-benzoquinone reductase (NADPH) activity Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+). MetaCyc:1.6.5.6-RXN|EC:1.6.5.6|RHEA:23488|KEGG_REACTION:R05244|UM-BBD_enzymeID:e0422 go-plus.json NADPH:p-benzoquinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018541 GO:0018544 biolink:MolecularActivity 4-carboxy-4'-sulfoazobenzene reductase activity Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate. UM-BBD_reactionID:r0543 go-plus.json 4-carboxy-4'-sulphoazobenzene reductase activity http://purl.obolibrary.org/obo/GO_0018544 GO:0018543 biolink:MolecularActivity 4-amino-2-nitroso-6-nitrotoluene reductase activity Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene. UM-BBD_reactionID:r0464 go-plus.json http://purl.obolibrary.org/obo/GO_0018543 GO:0018540 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018540 OBO:GOCHE_35469 biolink:OntologyClass substance with antidepressant role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35469 3_STAR CHEBI:138897 biolink:ChemicalSubstance 3',5'-unsubstituted flavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_138897 chebi_ph7_3 GO:0018557 biolink:MolecularActivity 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid. EC:1.13.11.-|UM-BBD_reactionID:r0422 go-plus.json http://purl.obolibrary.org/obo/GO_0018557 GO:0018556 biolink:MolecularActivity 2,2',3-trihydroxybiphenyl dioxygenase activity Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate). UM-BBD_enzymeID:e0032|EC:1.13.11.- go-plus.json http://purl.obolibrary.org/obo/GO_0018556 GO:0018559 biolink:MolecularActivity 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate. EC:1.13.11.-|UM-BBD_reactionID:r0442 go-plus.json 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018559 GO:0018558 biolink:MolecularActivity 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon. EC:1.13.11.-|UM-BBD_reactionID:r0049 go-plus.json http://purl.obolibrary.org/obo/GO_0018558 GO:0018553 biolink:MolecularActivity 3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate. UM-BBD_enzymeID:e0309 go-plus.json http://purl.obolibrary.org/obo/GO_0018553 GO:0018552 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018552 GO:0018555 biolink:MolecularActivity phenanthrene dioxygenase activity Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene. EC:1.13.11.-|UM-BBD_reactionID:r0455 go-plus.json http://purl.obolibrary.org/obo/GO_0018555 CHEBI:138890 biolink:ChemicalSubstance peregrinol diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138890 GO:0018554 biolink:MolecularActivity 1,2-dihydroxynaphthalene dioxygenase activity Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached. RHEA:27310|EC:1.13.11.56|UM-BBD_enzymeID:e0255 go-plus.json http://purl.obolibrary.org/obo/GO_0018554 GO:0018551 biolink:MolecularActivity hydrogensulfite reductase activity Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor. MetaCyc:HYDROGENSULFITE-REDUCTASE-RXN|UM-BBD_reactionID:r0627|EC:1.8.99.3|RHEA:13209 go-plus.json desulfoviridin activity|desulforubidin activity|desulfofuscidin activity|dissimilatory sulfite reductase activity|dissimilatory-type sulfite reductase activity|trithionate:(acceptor) oxidoreductase activity|hydrogensulphite reductase activity|bisulfite reductase activity|trithionate:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018551 GO:0018550 biolink:MolecularActivity tetrachloro-p-hydroquinone reductive dehalogenase activity Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl. UM-BBD_reactionID:r0314|EC:1.8.99.- go-plus.json tetrachlorohydroquinone reductive dehalogenase activity http://purl.obolibrary.org/obo/GO_0018550 CHEBI:138893 biolink:ChemicalSubstance Man-1-6-Ins-1-P-Cer(d18:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138893 chebi_ph7_3 GO:0102470 biolink:MolecularActivity 6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+. MetaCyc:RXN-14075 go-plus.json http://purl.obolibrary.org/obo/GO_0102470 GO:0102472 biolink:MolecularActivity eriodictyol 2-hydroxylase activity Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O. RHEA:57596|MetaCyc:RXN-14077 go-plus.json http://purl.obolibrary.org/obo/GO_0102472 GO:0102471 biolink:MolecularActivity 2-hydroxynaringenin-6C-glucoside dehydratase activity Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O. MetaCyc:RXN-14076 go-plus.json http://purl.obolibrary.org/obo/GO_0102471 GO:0102474 biolink:MolecularActivity eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+. MetaCyc:RXN-14080 go-plus.json http://purl.obolibrary.org/obo/GO_0102474 GO:0102473 biolink:MolecularActivity eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+. MetaCyc:RXN-14079 go-plus.json http://purl.obolibrary.org/obo/GO_0102473 GO:0102476 biolink:MolecularActivity pinocembrin 2-hydroxylase activity Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O. RHEA:57592|MetaCyc:RXN-14083 go-plus.json http://purl.obolibrary.org/obo/GO_0102476 GO:0102475 biolink:MolecularActivity 2-hydroxyeriodictyol 6C-glucoside dehydratase activity Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O. MetaCyc:RXN-14081 go-plus.json http://purl.obolibrary.org/obo/GO_0102475 GO:0102478 biolink:MolecularActivity beta-L-arabinofuranosidase activity Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose. RHEA:36051|EC:3.2.1.185|MetaCyc:RXN-14089 go-plus.json http://purl.obolibrary.org/obo/GO_0102478 GO:0102477 biolink:MolecularActivity 2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity Catalysis of the reaction: 6C-glucosyl-2,5,7-trihydroxyflavanone <=> H+ + 6C-hexosyl chrysin + H2O. MetaCyc:RXN-14088 go-plus.json http://purl.obolibrary.org/obo/GO_0102477 GO:0102479 biolink:MolecularActivity quercetin 3-O-beta:-D-galactosyltransferase activity Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+. EC:2.4.1.234|MetaCyc:RXN-14109 go-plus.json http://purl.obolibrary.org/obo/GO_0102479 CHEBI:44813 biolink:ChemicalSubstance N,N-dimethyl-L-prolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_44813 CHEBI:78141 biolink:ChemicalSubstance 1-heptadecylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78141 CHEBI:44811 biolink:ChemicalSubstance 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44811 chebi_ph7_3 CHEBI:78147 biolink:ChemicalSubstance fatty alcohol 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78147 chebi_ph7_3 CHEBI:78146 biolink:ChemicalSubstance trans-9-octadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78146 CHEBI:20847 biolink:ChemicalSubstance ADP-glycero-D-manno-heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_20847 GO:0102481 biolink:MolecularActivity 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+. RHEA:25836|EC:3.7.1.22|MetaCyc:RXN-14149 go-plus.json http://purl.obolibrary.org/obo/GO_0102481 GO:0102480 biolink:MolecularActivity 5-fluorocytosine deaminase activity Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium. EC:3.5.4.1|MetaCyc:RXN-14129 go-plus.json http://purl.obolibrary.org/obo/GO_0102480 GO:0102483 biolink:MolecularActivity scopolin beta-glucosidase activity Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin. MetaCyc:RXN-14179|EC:3.2.1.21 go-plus.json http://purl.obolibrary.org/obo/GO_0102483 GO:0102482 biolink:MolecularActivity 5-deoxy-D-glucuronate isomerase activity Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate. MetaCyc:RXN-14150|EC:5.3.1.30|RHEA:25840 go-plus.json http://purl.obolibrary.org/obo/GO_0102482 GO:0102485 biolink:MolecularActivity dATP phosphohydrolase activity Catalysis of the reaction: dATP + 2 H2O = dAMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14195|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102485 GO:0102484 biolink:MolecularActivity esculetin glucosyltransferase activity Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+. MetaCyc:RXN-14182 go-plus.json http://purl.obolibrary.org/obo/GO_0102484 GO:0102487 biolink:MolecularActivity dUTP phosphohydrolase activity Catalysis of the reaction: dUTP + 2 H2O = dUMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14199|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102487 GO:0102486 biolink:MolecularActivity dCTP phosphohydrolase activity Catalysis of the reaction: dCTP + 2 H2O = dCMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14198|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102486 GO:0102489 biolink:MolecularActivity GTP phosphohydrolase activity Catalysis of the reaction: GTP + 2 H2O = GMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14201|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102489 GO:0043500 biolink:BiologicalProcess muscle adaptation A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. go-plus.json muscle plasticity http://purl.obolibrary.org/obo/GO_0043500 goslim_pir GO:0102488 biolink:MolecularActivity dTTP phosphohydrolase activity Catalysis of the reaction: dTTP + 2 H2O = dTMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14200|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102488 GO:0043506 biolink:BiologicalProcess regulation of JUN kinase activity Any process that modulates the frequency, rate or extent of JUN kinase activity. go-plus.json regulation of JUNK activity http://purl.obolibrary.org/obo/GO_0043506 CHEBI:78150 biolink:ChemicalSubstance fatty alcohol 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78150 chebi_ph7_3 GO:0043505 biolink:CellularComponent CENP-A containing nucleosome A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3). go-plus.json centromere specific nucleosome|centromeric nucleosome|CNP-T-W-S-X complex|CENP-S-T-W-X|CenH3 containing nucleosome|centromere-specific nucleosome http://purl.obolibrary.org/obo/GO_0043505 GO:0043508 biolink:BiologicalProcess negative regulation of JUN kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity. go-plus.json negative regulation of JUNK activity|down-regulation of JNK activity|downregulation of JNK activity|down regulation of JNK activity|inhibition of JNK activity http://purl.obolibrary.org/obo/GO_0043508 GO:0043507 biolink:BiologicalProcess positive regulation of JUN kinase activity Any process that activates or increases the frequency, rate or extent of JUN kinase activity. go-plus.json up regulation of JNK activity|upregulation of JNK activity|stimulation of JNK activity|up-regulation of JNK activity|positive regulation of JUNK activity http://purl.obolibrary.org/obo/GO_0043507 GO:0043502 biolink:BiologicalProcess regulation of muscle adaptation Any process that modulates the frequency, rate or extent of muscle adaptation. go-plus.json regulation of muscle plasticity http://purl.obolibrary.org/obo/GO_0043502 GO:0043501 biolink:BiologicalProcess skeletal muscle adaptation Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. go-plus.json skeletal muscle plasticity http://purl.obolibrary.org/obo/GO_0043501 CHEBI:19835 biolink:ChemicalSubstance 3',5'-cyclic pyrimidine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_19835 CHEBI:19834 biolink:ChemicalSubstance 3',5'-cyclic purine nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_19834 GO:0043504 biolink:BiologicalProcess mitochondrial DNA repair The process of restoring mitochondrial DNA after damage. go-plus.json http://purl.obolibrary.org/obo/GO_0043504 GO:0043503 biolink:BiologicalProcess skeletal muscle fiber adaptation Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. go-plus.json skeletal muscle fiber plasticity|skeletal muscle fibre plasticity|skeletal myofiber plasticity|skeletal myofibre plasticity http://purl.obolibrary.org/obo/GO_0043503 CHEBI:44800 biolink:ChemicalSubstance (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_44800 chebi_ph7_3 CHEBI:20853 biolink:ChemicalSubstance AMP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_20853 CHEBI:20855 biolink:ChemicalSubstance ATP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_20855 CHEBI:20858 biolink:ChemicalSubstance C19-gibberellin go-plus.json http://purl.obolibrary.org/obo/CHEBI_20858 GO:0043509 biolink:CellularComponent activin A complex A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). go-plus.json http://purl.obolibrary.org/obo/GO_0043509 CHEBI:20857 biolink:ChemicalSubstance C-glycosyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_20857 CHEBI:20859 biolink:ChemicalSubstance C20-gibberellin go-plus.json http://purl.obolibrary.org/obo/CHEBI_20859 GO:0102490 biolink:MolecularActivity 8-oxo-dGTP phosphohydrolase activity Catalysis of the reaction: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14205|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102490 GO:0102491 biolink:MolecularActivity dGTP phosphohydrolase activity Catalysis of the reaction: dGTP + 2 H2O = dGMP + 2 hydrogenphosphate + 2 H+. MetaCyc:RXN-14208|EC:3.6.1.5 go-plus.json http://purl.obolibrary.org/obo/GO_0102491 GO:0102494 biolink:MolecularActivity GA20 2,3-desaturase activity Catalysis of the reaction: gibberellin A20 + O2 + a reduced electron acceptor <=> gibberellin A5 + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-14317 go-plus.json http://purl.obolibrary.org/obo/GO_0102494 GO:0102493 biolink:MolecularActivity wogonin 7-O-glucosyltransferase activity Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+. MetaCyc:RXN-14239 go-plus.json http://purl.obolibrary.org/obo/GO_0102493 GO:0102496 biolink:MolecularActivity GA5 2,3 epoxidase activity Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide. MetaCyc:RXN-14327 go-plus.json http://purl.obolibrary.org/obo/GO_0102496 GO:0102495 biolink:MolecularActivity GA5 3beta-hydroxylase activity Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A3 + succinate + carbon dioxide. MetaCyc:RXN-14318 go-plus.json http://purl.obolibrary.org/obo/GO_0102495 PR:000020841 biolink:Protein oncostatin-M proteolytic cleavage product An oncostatin-M that has been processed by proteolytic cleavage. go-plus.json OSM/ClvPrd http://purl.obolibrary.org/obo/PR_000020841 GO:0102498 biolink:MolecularActivity maltose glucosidase activity Catalysis of the reaction: H2O + maltose = 2 glucose. MetaCyc:RXN-15910 go-plus.json http://purl.obolibrary.org/obo/GO_0102498 UBERON:0005291 biolink:AnatomicalEntity embryonic tissue A portion of tissue that is part of an embryo. go-plus.json developing tissue|portion of embryonic tissue http://purl.obolibrary.org/obo/UBERON_0005291 GO:0102497 biolink:MolecularActivity scyllo-inositol dehydrogenase (NADP+) activity Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+. RHEA:39063|MetaCyc:RXN-14347|EC:1.1.1.371 go-plus.json http://purl.obolibrary.org/obo/GO_0102497 UBERON:0005290 biolink:AnatomicalEntity myelencephalon The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. go-plus.json myelencephalon (medulla oblongata) http://purl.obolibrary.org/obo/UBERON_0005290 GO:0043511 biolink:CellularComponent inhibin complex Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B. go-plus.json http://purl.obolibrary.org/obo/GO_0043511 goslim_pir GO:0043510 biolink:CellularComponent activin B complex A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B). go-plus.json http://purl.obolibrary.org/obo/GO_0043510 GO:0102499 biolink:MolecularActivity SHG alpha-glucan phosphorylase activity Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan. EC:2.4.1.1|MetaCyc:RXN-14353|RHEA:41732 go-plus.json http://purl.obolibrary.org/obo/GO_0102499 GO:0043517 biolink:BiologicalProcess positive regulation of DNA damage response, signal transduction by p53 class mediator Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. go-plus.json stimulation of DNA damage response, signal transduction by p53 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator|activation of DNA damage response, signal transduction by p53 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of p53 induced by DNA damage response|upregulation of DNA damage response, signal transduction by p53 class mediator http://purl.obolibrary.org/obo/GO_0043517 UBERON:0005298 biolink:AnatomicalEntity skin of clitoris A zone of skin that is part of a clitoris [Automatically generated definition]. go-plus.json clitoris skin http://purl.obolibrary.org/obo/UBERON_0005298 GO:0043516 biolink:BiologicalProcess regulation of DNA damage response, signal transduction by p53 class mediator Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. go-plus.json regulation of p53 induced by DNA damage response http://purl.obolibrary.org/obo/GO_0043516 UBERON:0005297 biolink:AnatomicalEntity testis sex cord The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]. go-plus.json testis cord|testis primary sex cords|primary sex cord|testis primitive sex cord http://purl.obolibrary.org/obo/UBERON_0005297 GO:0043519 biolink:BiologicalProcess regulation of myosin II filament organization Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules. go-plus.json regulation of myosin II filament assembly or disassembly|regulation of myosin II filament organisation http://purl.obolibrary.org/obo/GO_0043519 UBERON:0005296 biolink:AnatomicalEntity ovary sex cord structures that develop from sex cords in the female. After further development they become the ovarian follicles. go-plus.json cortical cord|secondary cord|ovigerous cord|cortical sex cord|ovigerous cords|ovary primitive sex cord http://purl.obolibrary.org/obo/UBERON_0005296 GO:0043518 biolink:BiologicalProcess negative regulation of DNA damage response, signal transduction by p53 class mediator Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. go-plus.json down-regulation of DNA damage response, signal transduction by p53 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of p53 induced by DNA damage response|down regulation of DNA damage response, signal transduction by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator http://purl.obolibrary.org/obo/GO_0043518 UBERON:0005295 biolink:AnatomicalEntity sex cord Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female. go-plus.json gonadal cord|genital cord|gonad cord|primitive sex cord http://purl.obolibrary.org/obo/UBERON_0005295 GO:0043513 biolink:CellularComponent inhibin B complex Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0043513 CHEBI:78165 biolink:ChemicalSubstance 1-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78165 GO:0043512 biolink:CellularComponent inhibin A complex Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0043512 UBERON:0005294 biolink:AnatomicalEntity gonadal ridge the elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary go-plus.json gonadal ridge|crista gonadalis|indifferent gonadal ridge|genital cord|genital ridge http://purl.obolibrary.org/obo/UBERON_0005294 CHEBI:78164 biolink:ChemicalSubstance 1-(9Z,12Z)-octadecadienylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78164 GO:0043515 biolink:MolecularActivity kinetochore binding Binding to a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached. go-plus.json http://purl.obolibrary.org/obo/GO_0043515 CHEBI:78163 biolink:ChemicalSubstance 1-octadecylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78163 GO:0043514 biolink:CellularComponent interleukin-12 complex A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space. go-plus.json IL12B|IL12A|p35|p40|IL-12 complex http://purl.obolibrary.org/obo/GO_0043514 UBERON:0005292 biolink:AnatomicalEntity extraembryonic tissue Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. go-plus.json extra-embryonic tissue http://purl.obolibrary.org/obo/UBERON_0005292 CHEBI:78169 biolink:ChemicalSubstance monoalkylglycerophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78169 chebi_ph7_3 CHEBI:78168 biolink:ChemicalSubstance 1-alkylglycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78168 chebi_ph7_3 CHEBI:78167 biolink:ChemicalSubstance 1-lysophosphatidate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78167 chebi_ph7_3 CHEBI:78166 biolink:ChemicalSubstance 2-lysophosphatidate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78166 chebi_ph7_3 GO:0043520 biolink:BiologicalProcess regulation of myosin II filament assembly Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0043520 GO:0043522 biolink:MolecularActivity leucine zipper domain binding Binding to a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns. go-plus.json leucine zipper binding http://purl.obolibrary.org/obo/GO_0043522 GO:0043521 biolink:BiologicalProcess regulation of myosin II filament disassembly Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0043521 GO:0043528 biolink:CellularComponent tRNA (m2G10) methyltransferase complex A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p. go-plus.json http://purl.obolibrary.org/obo/GO_0043528 UBERON:0005288 biolink:AnatomicalEntity tela choroidea of third ventricle Tela chorioidea that lines the third ventricle[ZFA]. The part of the choroid plexus in relation to the body of the ventricle forms the vascular fringed margin of a triangular process of pia mater, named the tela chorioidea of the third ventricle, and projects from under cover of the lateral edge of the fornix. Blood is supplied by branches from the superior cerebellar artery[WP]. go-plus.json tela choroidea ventriculi tertii|tela chorioidea third ventricle|tela chorioidea of third ventricle|choroid membrane of third ventricle|tela choroidea ventriculi tertii|tela choroidea third ventricle http://purl.obolibrary.org/obo/UBERON_0005288 CHEBI:78172 biolink:ChemicalSubstance monoacylglycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78172 chebi_ph7_3 UBERON:0005287 biolink:AnatomicalEntity tela choroidea of fourth ventricle Tela chorioidea that lines the fourth ventricle[ZFA]. The tela chorioidea of the fourth ventricle is the name applied to the triangular fold of pia mater which is carried upward between the cerebellum and the medulla oblongata. It consists of two layers, which are continuous with each other in front, and are more or less adherent throughout: The posterior layer covers the antero-inferior surface of the cerebellum. The anterior layer is applied to the structures which form the lower part of the roof of the ventricle, and is continuous inferiorly with the pia mater on the inferior peduncles and closed part of the medulla[WP]. go-plus.json tela choroidea|tela choroidea of fourth ventricle|tela choroidea ventriculi quarti|choroid membrane|tela choroidea ventriculi quarti|tela chorioidea fourth ventricle|tela choroidea fourth ventricle|choroid membrane of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0005287 GO:0043527 biolink:CellularComponent tRNA methyltransferase complex A multimeric protein complex involved in the methylation of specific nucleotides in tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0043527 goslim_pir CHEBI:78171 biolink:ChemicalSubstance monoalkenylglycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78171 chebi_ph7_3 CHEBI:78170 biolink:ChemicalSubstance 1-acylglycerophosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78170 chebi_ph7_3 GO:0043529 biolink:CellularComponent GET complex An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0043529 GO:0043524 biolink:BiologicalProcess negative regulation of neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. go-plus.json down-regulation of neuron apoptosis|negative regulation of programmed cell death, neurons|downregulation of neuron apoptosis|down regulation of neuron apoptosis|inhibition of neuron apoptosis|neuron survival|negative regulation of neuron apoptosis http://purl.obolibrary.org/obo/GO_0043524 CHEBI:78176 biolink:ChemicalSubstance undecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78176 GO:0043523 biolink:BiologicalProcess regulation of neuron apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. go-plus.json regulation of neuronal cell programmed cell death|regulation of neuron apoptosis|regulation of apoptosis of neurons|regulation of apoptosis of neuronal cells|regulation of neuron programmed cell death|regulation of programmed cell death of neuronal cells|regulation of programmed cell death, neurons http://purl.obolibrary.org/obo/GO_0043523 CHEBI:78175 biolink:ChemicalSubstance 1-arachidonoylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78175 UBERON:0005283 biolink:AnatomicalEntity tela choroidea A structure found in the walls of the ventricles of the brain, consisting of part of the meninges (pia mater in mammals) plus ependyma[cjm]. go-plus.json tela chorioidea http://purl.obolibrary.org/obo/UBERON_0005283 GO:0043526 biolink:BiologicalProcess obsolete neuroprotection OBSOLETE. Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss. Wikipedia:Neuroprotection go-plus.json neuroprotection http://purl.obolibrary.org/obo/GO_0043526 CHEBI:78174 biolink:ChemicalSubstance 1-(alk-1-enyl)-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78174 chebi_ph7_3 UBERON:0005282 biolink:AnatomicalEntity ventricular system of brain go-plus.json brain ventricular system http://purl.obolibrary.org/obo/UBERON_0005282 UBERON:0005281 biolink:AnatomicalEntity ventricular system of central nervous system A set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord[WP]. go-plus.json ventricular system|ventricular system of neuraxis|CNS ventricular system|ventriculi cerebri|ventricle system http://purl.obolibrary.org/obo/UBERON_0005281 GO:0043525 biolink:BiologicalProcess positive regulation of neuron apoptotic process Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. go-plus.json up regulation of neuron apoptosis|positive regulation of programmed cell death, neurons|upregulation of neuron apoptosis|stimulation of neuron apoptosis|activation of neuron apoptosis|up-regulation of neuron apoptosis|positive regulation of neuron apoptosis http://purl.obolibrary.org/obo/GO_0043525 CHEBI:78173 biolink:ChemicalSubstance 1-linoleoylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78173 CHEBI:78179 biolink:ChemicalSubstance trans-2-heptadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78179 CHEBI:78178 biolink:ChemicalSubstance (2E,9Z)-hexadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78178 CHEBI:78177 biolink:ChemicalSubstance trans-2-undecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78177 UBERON:0005289 biolink:AnatomicalEntity tela choroidea of telencephalic ventricle Tela chorioidea that lines the telencephalic ventricle. go-plus.json tela choroidea of lateral ventricle|tela choroidea telencephalic ventricle|tela chorioidea telencephalic ventricle|tela chorioidea of telencephalic ventricle|tela choroidea (ventriculi lateralis)|tela chorioidea of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0005289 GO:0102430 biolink:MolecularActivity alpha-linolenate delta5 desaturase activity Catalysis of the reaction: alpha-linolenate + O2 + a reduced electron acceptor = coniferonate + 2 H2O + an oxidized electron acceptor. RHEA:38039|MetaCyc:RXN-13857 go-plus.json http://purl.obolibrary.org/obo/GO_0102430 GO:0043531 biolink:MolecularActivity ADP binding Binding to ADP, adenosine 5'-diphosphate. go-plus.json adenosine diphosphate binding|adenosine 5'-diphosphate binding http://purl.obolibrary.org/obo/GO_0043531 GO:0102432 biolink:MolecularActivity quercetin 7-O-methyltransferase activity Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine <=> rhamnetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13906 go-plus.json http://purl.obolibrary.org/obo/GO_0102432 GO:0102431 biolink:MolecularActivity acyl-lipid omega-(9-4) desaturase Catalysis of the reaction: linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H(+) <=> pinolenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O. RHEA:46236|MetaCyc:RXN-13858|EC:1.14.19.12 go-plus.json linoleate delta5 desaturase activity http://purl.obolibrary.org/obo/GO_0102431 GO:0043530 biolink:MolecularActivity adenosine 5'-monophosphoramidase activity Catalysis of the reaction: adenosine 5'-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester. go-plus.json adenosine 5' monophosphoramidase activity|adenosine 5'-monophosphoramidate hydrolase activity http://purl.obolibrary.org/obo/GO_0043530 GO:0102434 biolink:MolecularActivity pterin-4alpha-carbinolamine dehydratase activity Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate. MetaCyc:RXN-13908 go-plus.json http://purl.obolibrary.org/obo/GO_0102434 GO:0043533 biolink:MolecularActivity inositol 1,3,4,5 tetrakisphosphate binding Binding to inositol 1,3,4,5 tetrakisphosphate. go-plus.json InsP4 binding|IP4 binding http://purl.obolibrary.org/obo/GO_0043533 NCBITaxon:1489908 biolink:OrganismalEntity Ovalentaria go-plus.json Stiassnyiformes http://purl.obolibrary.org/obo/NCBITaxon_1489908 GO:0043532 biolink:MolecularActivity angiostatin binding Binding to angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043532 GO:0102433 biolink:MolecularActivity phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity Catalysis of the reaction: L-phenylalanine + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine + a 10-formyltetrahydrofolate-4a-carbinolamine. MetaCyc:RXN-13907 go-plus.json http://purl.obolibrary.org/obo/GO_0102433 GO:0102436 biolink:MolecularActivity 7-methylmyricetin 4'-O-methyltransferase activity Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13911 go-plus.json http://purl.obolibrary.org/obo/GO_0102436 CHEBI:78190 biolink:ChemicalSubstance (2E,9Z,12Z)-octadecatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78190 GO:0102435 biolink:MolecularActivity myricetin 7-O-methyltransferase activity Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13910 go-plus.json http://purl.obolibrary.org/obo/GO_0102435 GO:0102438 biolink:MolecularActivity laricitrin 4'-O-methyltransferase activity Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13914 go-plus.json http://purl.obolibrary.org/obo/GO_0102438 GO:0102437 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102437 CHEBI:78183 biolink:ChemicalSubstance 1-alkenyl-2-acyl-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78183 chebi_ph7_3 GO:0043539 biolink:MolecularActivity protein serine/threonine kinase activator activity Binds to and increases the activity of a protein serine/threonine kinase. go-plus.json protein ser/thr kinase activator activity http://purl.obolibrary.org/obo/GO_0043539 CHEBI:78182 biolink:ChemicalSubstance 1-alkyl-2-acyl-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78182 chebi_ph7_3 GO:0043538 biolink:BiologicalProcess regulation of actin phosphorylation Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043538 GO:0102439 biolink:MolecularActivity 3',4',5'-trimethylmyricetin 7-O-methyltransferase activity Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13916 go-plus.json http://purl.obolibrary.org/obo/GO_0102439 CHEBI:78181 biolink:ChemicalSubstance (2E,9E)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78181 GO:0043535 biolink:BiologicalProcess regulation of blood vessel endothelial cell migration Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0043535 CHEBI:78187 biolink:ChemicalSubstance (2E,9Z)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_78187 GO:0043534 biolink:BiologicalProcess blood vessel endothelial cell migration The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043534 CHEBI:78186 biolink:ChemicalSubstance 1-alkyl-2-acyl-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78186 chebi_ph7_3 CHEBI:78185 biolink:ChemicalSubstance glycero-3-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78185 chebi_ph7_3 GO:0043537 biolink:BiologicalProcess negative regulation of blood vessel endothelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. go-plus.json down-regulation of blood vessel endothelial cell migration|inhibition of blood vessel endothelial cell migration|down regulation of blood vessel endothelial cell migration|downregulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0043537 GO:0043536 biolink:BiologicalProcess positive regulation of blood vessel endothelial cell migration Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. go-plus.json stimulation of blood vessel endothelial cell migration|up-regulation of blood vessel endothelial cell migration|upregulation of blood vessel endothelial cell migration|up regulation of blood vessel endothelial cell migration|activation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0043536 CHEBI:78184 biolink:ChemicalSubstance monoalkylmonoacylglycerolphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78184 chebi_ph7_3 CHEBI:78189 biolink:ChemicalSubstance alkylacylglycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78189 chebi_ph7_3 CHEBI:78188 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78188 chebi_ph7_3 CHEBI:20805 biolink:ChemicalSubstance (+)-8'-hydroxyabscisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20805 NCBITaxon:1489913 biolink:OrganismalEntity Atherinomorphae go-plus.json Atherinomorpha http://purl.obolibrary.org/obo/NCBITaxon_1489913 GO:0102441 biolink:MolecularActivity syringetin 7-O-methyltransferase activity Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13919 go-plus.json http://purl.obolibrary.org/obo/GO_0102441 GO:0102440 biolink:MolecularActivity 3',4',5'-trimethylmyricetin 3-O-methyltransferase activity Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13918 go-plus.json http://purl.obolibrary.org/obo/GO_0102440 GO:0102443 biolink:MolecularActivity L-2-hydroxycarboxylate dehydrogenase (NAD+) activity Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate. RHEA:34555|MetaCyc:RXN-13927|EC:1.1.1.337 go-plus.json http://purl.obolibrary.org/obo/GO_0102443 GO:0043542 biolink:BiologicalProcess endothelial cell migration The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. go-plus.json http://purl.obolibrary.org/obo/GO_0043542 GO:0102442 biolink:MolecularActivity syringetin 3-O-methyltransferase activity Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13920 go-plus.json http://purl.obolibrary.org/obo/GO_0102442 GO:0043541 biolink:CellularComponent UDP-N-acetylglucosamine transferase complex A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0043541 GO:0102445 biolink:MolecularActivity 3-methylquercetin 3'-O-methyltransferase activity Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13930 go-plus.json http://purl.obolibrary.org/obo/GO_0102445 GO:0043544 biolink:MolecularActivity lipoamide binding Binding to lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group. go-plus.json http://purl.obolibrary.org/obo/GO_0043544 GO:0043543 biolink:BiologicalProcess protein acylation The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid. go-plus.json protein amino acid acylation http://purl.obolibrary.org/obo/GO_0043543 goslim_yeast GO:0102444 biolink:MolecularActivity isorhamnetin 3-O-methyltransferase activity Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine. MetaCyc:RXN-13929 go-plus.json http://purl.obolibrary.org/obo/GO_0102444 GO:0102447 biolink:MolecularActivity rhamnetin 3'-O-methyltransferase activity Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13933 go-plus.json http://purl.obolibrary.org/obo/GO_0102447 GO:0102446 biolink:MolecularActivity rhamnetin 3-O-methyltransferase activity Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13932 go-plus.json http://purl.obolibrary.org/obo/GO_0102446 GO:0043540 biolink:CellularComponent 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis. go-plus.json 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex http://purl.obolibrary.org/obo/GO_0043540 GO:0102449 biolink:MolecularActivity kaempferol 3-O-methyltransferase activity Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine. MetaCyc:RXN-13935 go-plus.json http://purl.obolibrary.org/obo/GO_0102449 GO:0102448 biolink:MolecularActivity rhamnetin 4'-O-methyltransferase activity Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> ombuin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13934 go-plus.json http://purl.obolibrary.org/obo/GO_0102448 CHEBI:78194 biolink:ChemicalSubstance (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-coenzyme A go-plus.json http://purl.obolibrary.org/obo/CHEBI_78194 GO:0043549 biolink:BiologicalProcess regulation of kinase activity Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043549 CHEBI:78193 biolink:ChemicalSubstance 1-alkylglycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78193 chebi_ph7_3 CHEBI:78192 biolink:ChemicalSubstance 1-lysophosphatidylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78192 chebi_ph7_3 CHEBI:78191 biolink:ChemicalSubstance 2-lysophosphatidylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78191 chebi_ph7_3 CHEBI:78198 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78198 chebi_ph7_3 GO:0043546 biolink:MolecularActivity molybdopterin cofactor binding Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. go-plus.json Moco binding http://purl.obolibrary.org/obo/GO_0043546 GO:0043545 biolink:BiologicalProcess molybdopterin cofactor metabolic process The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. go-plus.json Moco metabolism|Moco metabolic process|molybdopterin cofactor metabolism http://purl.obolibrary.org/obo/GO_0043545 CHEBI:78197 biolink:ChemicalSubstance 1-alkyl-2-acyl-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78197 chebi_ph7_3 GO:0043548 biolink:MolecularActivity phosphatidylinositol 3-kinase binding Binding to a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring. go-plus.json PI3K binding|phosphoinositide 3-kinase binding http://purl.obolibrary.org/obo/GO_0043548 CHEBI:78196 biolink:ChemicalSubstance monoalkylglycerophosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78196 chebi_ph7_3 GO:0043547 biolink:BiologicalProcess positive regulation of GTPase activity Any process that activates or increases the activity of a GTPase. go-plus.json up regulation of ARF GTPase activity|stimulation of Ran GTPase activity|up regulation of Rac GTPase activity|up-regulation of Rap GTPase activity|up regulation of Rab GTPase activity|up-regulation of Cdc42 GTPase activity|positive regulation of ARF GTPase activity|stimulation of Ral GTPase activity|positive regulation of Rac GTPase activity|up-regulation of Ran GTPase activity|positive regulation of Rab GTPase activity|up-regulation of Ral GTPase activity|stimulation of Rho GTPase activity|up-regulation of GTPase activity|upregulation of Ras GTPase activity|up-regulation of Rho GTPase activity|stimulation of ARF GTPase activity|upregulation of Rap GTPase activity|upregulation of Cdc42 GTPase activity|stimulation of Rac GTPase activity|stimulation of Rab GTPase activity|upregulation of Ran GTPase activity|up-regulation of ARF GTPase activity|upregulation of Ral GTPase activity|up-regulation of Rac GTPase activity|up-regulation of Rab GTPase activity|upregulation of GTPase activity|up regulation of Ras GTPase activity|upregulation of Rho GTPase activity|positive regulation of Ras GTPase activity|up regulation of Rap GTPase activity|up regulation of Cdc42 GTPase activity|up regulation of Ran GTPase activity|upregulation of ARF GTPase activity|positive regulation of Rap GTPase activity|upregulation of Rac GTPase activity|positive regulation of Cdc42 GTPase activity|up regulation of Ral GTPase activity|positive regulation of Ran GTPase activity|upregulation of Rab GTPase activity|positive regulation of Ral GTPase activity|up regulation of GTPase activity|stimulation of Ras GTPase activity|up regulation of Rho GTPase activity|activation of GTPase activity|up-regulation of Ras GTPase activity|stimulation of Rap GTPase activity|positive regulation of Rho GTPase activity|stimulation of GTPase activity|stimulation of Cdc42 GTPase activity http://purl.obolibrary.org/obo/GO_0043547 CHEBI:78195 biolink:ChemicalSubstance 1-(alk-1-enyl)glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78195 chebi_ph7_3 CHEBI:78199 biolink:ChemicalSubstance alkylacylglycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78199 chebi_ph7_3 CHEBI:20814 biolink:ChemicalSubstance phenanthrene-9,10-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_20814 chebi_ph7_3 GO:0102450 biolink:MolecularActivity kaempferide 7-O-methyltransferase activity Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine. MetaCyc:RXN-13936 go-plus.json http://purl.obolibrary.org/obo/GO_0102450 GO:0102452 biolink:MolecularActivity bisdemethoxycurcumin synthase activity Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide. MetaCyc:RXN-13958|EC:2.3.1.211|RHEA:34803 go-plus.json http://purl.obolibrary.org/obo/GO_0102452 PR:000044813 biolink:Protein glycoprotein hormone beta chain A protein with a core domain composition consisting of a signal peptide followed by a single copy of the Cys_knot (Pfam:PF00007) domain. The Cysteine knot is a protein structural motif containing three disulfide bridges. go-plus.json http://purl.obolibrary.org/obo/PR_000044813 GO:0102451 biolink:MolecularActivity kaempferide 3-O-methyltransferase activity Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine. MetaCyc:RXN-13937 go-plus.json http://purl.obolibrary.org/obo/GO_0102451 GO:0043553 biolink:BiologicalProcess negative regulation of phosphatidylinositol 3-kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity. go-plus.json downregulation of phosphatidylinositol 3-kinase activity|negative regulation of phosphoinositide 3-kinase activity|down regulation of phosphatidylinositol 3-kinase activity|inhibition of phosphatidylinositol 3-kinase activity|down-regulation of phosphatidylinositol 3-kinase activity|negative regulation of PI3K activity http://purl.obolibrary.org/obo/GO_0043553 GO:0102454 biolink:MolecularActivity cyanidin 3-O-galactosyltransferase activity Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP. RHEA:35631|EC:2.4.1.294|MetaCyc:RXN-13960 go-plus.json http://purl.obolibrary.org/obo/GO_0102454 GO:0043552 biolink:BiologicalProcess positive regulation of phosphatidylinositol 3-kinase activity Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity. go-plus.json positive regulation of phosphoinositide 3-kinase activity|upregulation of phosphatidylinositol 3-kinase activity|stimulation of phosphatidylinositol 3-kinase activity|activation of phosphatidylinositol 3-kinase activity|up-regulation of phosphatidylinositol 3-kinase activity|up regulation of phosphatidylinositol 3-kinase activity http://purl.obolibrary.org/obo/GO_0043552 GO:0102453 biolink:MolecularActivity anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside]. RHEA:35411|EC:2.3.1.215|MetaCyc:RXN-13959 go-plus.json http://purl.obolibrary.org/obo/GO_0102453 GO:0043555 biolink:BiologicalProcess regulation of translation in response to stress Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json translational stress response http://purl.obolibrary.org/obo/GO_0043555 GO:0102456 biolink:MolecularActivity cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose <=> cyanin betaine + trans-sinapate + H+. MetaCyc:RXN-13967 go-plus.json http://purl.obolibrary.org/obo/GO_0102456 GO:0043554 biolink:BiologicalProcess aerobic respiration, using arsenite as electron donor The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems. go-plus.json http://purl.obolibrary.org/obo/GO_0043554 GO:0102455 biolink:MolecularActivity anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside. EC:2.4.1.297|MetaCyc:RXN-13965|RHEA:35419 go-plus.json http://purl.obolibrary.org/obo/GO_0102455 GO:0102458 biolink:MolecularActivity cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+. EC:2.4.1.299|MetaCyc:RXN-13970 go-plus.json http://purl.obolibrary.org/obo/GO_0102458 GO:0102457 biolink:MolecularActivity cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> H+ + cyanidin 3,7-di-O-beta-D-glucoside betaine + vanillate. RHEA:35431|EC:2.4.1.300|MetaCyc:RXN-13969 go-plus.json http://purl.obolibrary.org/obo/GO_0102457 GO:0043551 biolink:BiologicalProcess regulation of phosphatidylinositol 3-kinase activity Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring. go-plus.json regulation of phosphoinositide 3-kinase activity http://purl.obolibrary.org/obo/GO_0043551 GO:0043550 biolink:BiologicalProcess regulation of lipid kinase activity Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0043550 GO:0102459 biolink:MolecularActivity 8-oxo-deoxyadenine diphosphate phosphatase activity Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+. MetaCyc:RXN-14005 go-plus.json http://purl.obolibrary.org/obo/GO_0102459 GO:0043557 biolink:BiologicalProcess regulation of translation in response to osmotic stress Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043557 GO:0043556 biolink:BiologicalProcess regulation of translation in response to oxidative stress Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0043556 GO:0043559 biolink:MolecularActivity insulin binding Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0043559 GO:0043558 biolink:BiologicalProcess regulation of translational initiation in response to stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress. go-plus.json regulation of translation initiation in response to stress http://purl.obolibrary.org/obo/GO_0043558 GO:0102461 biolink:MolecularActivity kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP. MetaCyc:RXN-14009 go-plus.json http://purl.obolibrary.org/obo/GO_0102461 GO:0102460 biolink:MolecularActivity kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP. MetaCyc:RXN-14008 go-plus.json http://purl.obolibrary.org/obo/GO_0102460 GO:0102463 biolink:MolecularActivity quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose <=> quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+. MetaCyc:RXN-14012 go-plus.json http://purl.obolibrary.org/obo/GO_0102463 GO:0102462 biolink:MolecularActivity quercetin 3-sophoroside 7-O-rhamnosyltransferase activity Catalysis of the reaction: quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> quercetin 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP + H+. MetaCyc:RXN-14011 go-plus.json http://purl.obolibrary.org/obo/GO_0102462 GO:0102465 biolink:MolecularActivity zeaxanthin 2,2'-beta-hydroxylase activity Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O. MetaCyc:RXN-14018 go-plus.json http://purl.obolibrary.org/obo/GO_0102465 GO:0043564 biolink:CellularComponent Ku70:Ku80 complex Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK. go-plus.json Ku70:Ku80 heterodimer http://purl.obolibrary.org/obo/GO_0043564 GO:0102464 biolink:MolecularActivity zeaxanthin 2-beta-hydroxylase activity Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD. MetaCyc:RXN-14016 go-plus.json http://purl.obolibrary.org/obo/GO_0102464 GO:0043563 biolink:MolecularActivity obsolete odorant transporter activity OBSOLETE. Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells. go-plus.json http://purl.obolibrary.org/obo/GO_0043563 GO:0102467 biolink:MolecularActivity scutellarein 7-O-glucuronosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+. MetaCyc:RXN-14058|RHEA:28318|EC:2.4.1.253 go-plus.json http://purl.obolibrary.org/obo/GO_0102467 GO:0043566 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043566 GO:0043565 biolink:MolecularActivity sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. go-plus.json sequence specific DNA binding http://purl.obolibrary.org/obo/GO_0043565 GO:0102466 biolink:MolecularActivity beta-carotene 2,2'-beta-hydroxylase activity Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O. MetaCyc:RXN-14019 go-plus.json http://purl.obolibrary.org/obo/GO_0102466 GO:0043560 biolink:MolecularActivity insulin receptor substrate binding Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. go-plus.json IRS binding|insulin receptor substrate [protein] binding|IRS [protein] binding http://purl.obolibrary.org/obo/GO_0043560 GO:0102469 biolink:MolecularActivity naringenin 2-hydroxylase activity Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O. MetaCyc:RXN-14069|RHEA:57588 go-plus.json http://purl.obolibrary.org/obo/GO_0102469 GO:0102468 biolink:MolecularActivity wogonin 7-O-glucuronosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+. EC:2.4.1.253|MetaCyc:RXN-14060|RHEA:28322 go-plus.json http://purl.obolibrary.org/obo/GO_0102468 GO:0043562 biolink:BiologicalProcess cellular response to nitrogen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0043562 GO:0043561 biolink:BiologicalProcess regulation of translational initiation in response to osmotic stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043561 GO:0043568 biolink:BiologicalProcess positive regulation of insulin-like growth factor receptor signaling pathway Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling. go-plus.json positive regulation of IGF receptor signalling pathway|up-regulation of insulin-like growth factor receptor signaling pathway|positive regulation of IGF receptor signaling pathway|upregulation of insulin-like growth factor receptor signaling pathway|positive regulation of insulin-like growth factor receptor signalling pathway|up regulation of insulin-like growth factor receptor signaling pathway|activation of insulin-like growth factor receptor signaling pathway|stimulation of insulin-like growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0043568 GO:0043567 biolink:BiologicalProcess regulation of insulin-like growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling. go-plus.json regulation of IGF receptor signaling pathway|regulation of insulin-like growth factor receptor signalling pathway|regulation of IGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0043567 GO:0043569 biolink:BiologicalProcess negative regulation of insulin-like growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling. go-plus.json inhibition of insulin-like growth factor receptor signaling pathway|negative regulation of IGF receptor signalling pathway|negative regulation of IGF receptor signaling pathway|down regulation of insulin-like growth factor receptor signaling pathway|negative regulation of insulin-like growth factor receptor signalling pathway|downregulation of insulin-like growth factor receptor signaling pathway|down-regulation of insulin-like growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0043569 CHEBI:29136 biolink:ChemicalSubstance pyridine N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29136 chebi_ph7_3 CHEBI:138905 biolink:ChemicalSubstance phosphatidic acid 36:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138905 CHEBI:29133 biolink:ChemicalSubstance dextrorphan go-plus.json http://purl.obolibrary.org/obo/CHEBI_29133 UBERON:0005352 biolink:AnatomicalEntity spermatic cord The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]. go-plus.json funiculus spermaticus|spermatic chord http://purl.obolibrary.org/obo/UBERON_0005352 UBERON:0005358 biolink:AnatomicalEntity ventricle of nervous system A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord. go-plus.json region of wall of ventricular system of neuraxis|ventricular layer http://purl.obolibrary.org/obo/UBERON_0005358 UBERON:0005356 biolink:AnatomicalEntity Rathke's pouch A pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland[MP]. In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system[WP]. go-plus.json pouch of Rathke|craniopharyngeal pouch|Rathkes pouch epithelium|Rathke pouch|pituitary diverticulum|craniobuccal pouch|nasohypophyseal pouch|adenohypophysial pouch|Rathke's cleft|hypophyseal diverticulum|Rathke's cyst|Rathke's pocket|hypophyseal pouch http://purl.obolibrary.org/obo/UBERON_0005356 CHEBI:138919 biolink:ChemicalSubstance meso-zeaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_138919 chebi_ph7_3 UBERON:0005343 biolink:AnatomicalEntity cortical plate The outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers[MP]. go-plus.json future cortical layers II-VI|CxP|neocortex cortical plate|CP|cerebral cortex cortical plate|future neocortex http://purl.obolibrary.org/obo/UBERON_0005343 UBERON:0005341 biolink:AnatomicalEntity ventral commissure The fiber tracts that connect the ventral region of the two cerebral hemispheres and span the longitudinal fissure, including the anterior and the habenular commissures[MP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005341 CHEBI:29152 biolink:ChemicalSubstance Cys-tRNA(Cys) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29152 UBERON:0005340 biolink:AnatomicalEntity dorsal telencephalic commissure A fiber tracts that connect the dorsal region of the two cerebral hemispheres and span the longitudinal fissure, including the corpus callosum and hippocampal commissure[MP]. go-plus.json dorsal commissure http://purl.obolibrary.org/obo/UBERON_0005340 CHEBI:30109 biolink:ChemicalSubstance 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_30109 chebi_ph7_3 CHEBI:29118 biolink:ChemicalSubstance methanophenazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29118 chebi_ph7_3 CHEBI:30106 biolink:ChemicalSubstance azo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30106 chebi_ph7_3 CHEBI:29119 biolink:ChemicalSubstance (2E,4Z)-deca-2,4-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_29119 CHEBI:30104 biolink:ChemicalSubstance diazanetriide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30104 CHEBI:29114 biolink:ChemicalSubstance 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29114 CHEBI:29110 biolink:ChemicalSubstance (+-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_29110 CHEBI:29112 biolink:ChemicalSubstance 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29112 CHEBI:29111 biolink:ChemicalSubstance alpha-D-GlcpNAc-(1->2)-[alpha-D-Manp-(1->3)]-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-D-Manp go-plus.json http://purl.obolibrary.org/obo/CHEBI_29111 chebi_ph7_3 UBERON:0005332 biolink:AnatomicalEntity mesonephric S-shaped body The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005332 UBERON:0005331 biolink:AnatomicalEntity mesonephric renal vesicle The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]. go-plus.json mesonephric vesicle http://purl.obolibrary.org/obo/UBERON_0005331 UBERON:0005330 biolink:AnatomicalEntity mesonephric nephron epithelium The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005330 CHEBI:114953 biolink:ChemicalSubstance (2S)-2-ammonio-5-{[iminio(methylamino)methyl]amino}pentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_114953 chebi_ph7_3 CHEBI:30103 biolink:ChemicalSubstance diazenide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30103 CHEBI:30102 biolink:ChemicalSubstance diazynium go-plus.json http://purl.obolibrary.org/obo/CHEBI_30102 UBERON:0005339 biolink:AnatomicalEntity outflow tract pulmonary component go-plus.json http://purl.obolibrary.org/obo/UBERON_0005339 UBERON:0005338 biolink:AnatomicalEntity outflow tract aortic component An outflow tract that is part of a aorta. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005338 CHEBI:30101 biolink:ChemicalSubstance hydrazine-1,1-diide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30101 UBERON:0005337 biolink:AnatomicalEntity outflow tract of ventricle A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]. go-plus.json heart ventricle outflow tract|outflow part of ventricle|ventricular outflow tract http://purl.obolibrary.org/obo/UBERON_0005337 CHEBI:30100 biolink:ChemicalSubstance hydrazine-1,2-diide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30100 UBERON:0005334 biolink:AnatomicalEntity oral lamina propria A lamina propria that is part of a mucosa of oral region. go-plus.json lamina propria of oral mucosa http://purl.obolibrary.org/obo/UBERON_0005334 UBERON:0005333 biolink:AnatomicalEntity mammary bud A bulb of epithelial cells that forms from the mammary placode that develops into the mammary gland. go-plus.json lactiferous gland bud|mammary gland bud|mammary primordium|milk bud http://purl.obolibrary.org/obo/UBERON_0005333 OBA:VT0000183 biolink:OntologyClass blood pressure trait The pressure of a blood. go-plus.json pressure of blood http://purl.obolibrary.org/obo/OBA_VT0000183 CHEBI:20794 biolink:ChemicalSubstance 7-methylguanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_20794 chebi_ph7_3 UBERON:0005319 biolink:AnatomicalEntity mesonephric collecting duct The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005319 CHEBI:29125 biolink:ChemicalSubstance arsenate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29125 CHEBI:29126 biolink:ChemicalSubstance trans-dec-3-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_29126 CHEBI:29121 biolink:ChemicalSubstance oxidonitrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29121 CHEBI:29123 biolink:ChemicalSubstance 2-acetamido-5-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29123 chebi_ph7_3 UBERON:0005321 biolink:AnatomicalEntity mesonephric smooth muscle tissue . go-plus.json http://purl.obolibrary.org/obo/UBERON_0005321 UBERON:0005320 biolink:AnatomicalEntity mesonephric juxtaglomerular apparatus The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005320 CHEBI:44747 biolink:ChemicalSubstance homogentisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44747 UBERON:0005329 biolink:AnatomicalEntity mesonephric nephron tubule A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros[GO]. go-plus.json mesonephric renal tubule http://purl.obolibrary.org/obo/UBERON_0005329 UBERON:0005328 biolink:AnatomicalEntity mesonephric comma-shaped body The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005328 UBERON:0005327 biolink:AnatomicalEntity mesonephric glomerular epithelium A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005327 UBERON:0005326 biolink:AnatomicalEntity mesonephric glomerulus vasculature The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005326 UBERON:0005325 biolink:AnatomicalEntity mesonephric glomerulus The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros[GO]. go-plus.json glomerulus http://purl.obolibrary.org/obo/UBERON_0005325 UBERON:0005324 biolink:AnatomicalEntity mesonephric macula densa The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005324 UBERON:0005323 biolink:AnatomicalEntity mesonephric mesenchyme Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005323 UBERON:0005322 biolink:AnatomicalEntity mesonephric nephron A nephron that is part of a mesonephros. go-plus.json stage IV nephron|nephron of mesonephros http://purl.obolibrary.org/obo/UBERON_0005322 CHEBI:78109 biolink:ChemicalSubstance 1-decyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78109 chebi_ph7_3 CHEBI:78108 biolink:ChemicalSubstance 1-decyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78108 chebi_ph7_3 UBERON:0005398 biolink:AnatomicalEntity female reproductive gland A sex gland that is part of a female reproductive system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005398 UBERON:0005397 biolink:AnatomicalEntity brain arachnoid mater An arachnoid mater that surrounds a brain. go-plus.json arachnoidea mater cranialis|brain arachnoid matter|cranial arachnoid mater|arachnoidea mater encephali http://purl.obolibrary.org/obo/UBERON_0005397 UBERON:0005396 biolink:AnatomicalEntity carotid artery segment One of: the common carotid artery, or its branches, the external and internal carotid arteries. go-plus.json carotid artery|subdivision of common carotid artery|carotid|common carotid arterial subdivision http://purl.obolibrary.org/obo/UBERON_0005396 NCBITaxon:112252 biolink:OrganismalEntity Fungi incertae sedis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_112252 CHEBI:78103 biolink:ChemicalSubstance 1-dodecyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78103 chebi_ph7_3 CHEBI:78102 biolink:ChemicalSubstance 1-tetradecyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78102 chebi_ph7_3 CHEBI:78101 biolink:ChemicalSubstance 1-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78101 chebi_ph7_3 CHEBI:78100 biolink:ChemicalSubstance trioxilin A3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78100 chebi_ph7_3 CHEBI:19763 biolink:ChemicalSubstance 2-phosphoglycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19763 CHEBI:78104 biolink:ChemicalSubstance 1-dodecyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78104 chebi_ph7_3 UBERON:0005399 biolink:AnatomicalEntity male reproductive gland A sex gland that is part of a male reproductive system. go-plus.json accessory sex gland http://purl.obolibrary.org/obo/UBERON_0005399 CHEBI:78119 biolink:ChemicalSubstance fatty acid anion 12:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78119 chebi_ph7_3 CHEBI:29107 biolink:ChemicalSubstance 24-methylidenelophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29107 chebi_ph7_3 CHEBI:29109 biolink:ChemicalSubstance (+-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29109 CHEBI:29108 biolink:ChemicalSubstance calcium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29108 chebi_ph7_3 CHEBI:29103 biolink:ChemicalSubstance potassium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29103 chebi_ph7_3 CHEBI:29105 biolink:ChemicalSubstance zinc(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29105 chebi_ph7_3 CHEBI:29101 biolink:ChemicalSubstance sodium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29101 chebi_ph7_3 UBERON:0005386 biolink:AnatomicalEntity olfactory segment of nasal mucosa That portion of the nasal mucosa containing the sensory endings for olfaction; the organ of smell[MESH]. go-plus.json pars olfactoria tunicae mucosae nasi|olfactory part of nasal mucosa|pars olfactoria tunicae mucosae nasi|olfactory area of nasal mucosa|olfactory zone of nasal mucosa|olfactory mucosa http://purl.obolibrary.org/obo/UBERON_0005386 UBERON:0005384 biolink:AnatomicalEntity nasal cavity epithelium An epithelium that lines the nasal cavity. go-plus.json nasal epithelium|nasal mucosa http://purl.obolibrary.org/obo/UBERON_0005384 UBERON:0005383 biolink:AnatomicalEntity caudate-putamen Regional part of telencephalon in some species, e.g., rodent, equivalent to the dorsal striatum (caudate nucleus and putamen). Unlike the dorsal striatum of primates, for example, the caudoputamen is not split into separate nuclei by the fibers of the internal capsule. Rather, the internal capsule splits into fiber bundles which course through the structure. go-plus.json caudate putamen|dorsal striatum|caudate putamen|caudoputamen|caudateputamen|striatum|caudateputamen|caudate-putamen|neostriatum|caudate putamen (striatum) http://purl.obolibrary.org/obo/UBERON_0005383 UBERON:0005382 biolink:AnatomicalEntity dorsal striatum Dorsal components of the striatum comprising the caudate nucleus and the putamen, in species that have distinct nuclei; the caudoputamen in species which don't. go-plus.json striatum dorsale|dorsal basal ganglia|striatum dorsal region|caudoputamen|corpus striatum|dorsal basal ganglion|striated body http://purl.obolibrary.org/obo/UBERON_0005382 UBERON:0005381 biolink:AnatomicalEntity dentate gyrus granule cell layer Granule cell layer is also called the DG principal cell layer. This one of the three layers of dentate gyrus that lies deep to the molecular layer and is made of densely packed layer that is four to eight granule cells thick. go-plus.json granular layer of the dentate gyrus|DG granule cell layer|stratum granulare gyri dentati|dentate gyrus, granule cell layer|granular layer of dentate gyrus http://purl.obolibrary.org/obo/UBERON_0005381 CHEBI:78114 biolink:ChemicalSubstance 1-tetradecylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78114 CHEBI:78113 biolink:ChemicalSubstance fatty acid anion 3:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78113 chebi_ph7_3 NCBITaxon:7586 biolink:OrganismalEntity Echinodermata go-plus.json echinoderms|echinoderms http://purl.obolibrary.org/obo/NCBITaxon_7586 CHEBI:78112 biolink:ChemicalSubstance 1-dodecylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78112 CHEBI:78111 biolink:ChemicalSubstance 1-oleylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78111 CHEBI:78118 biolink:ChemicalSubstance fatty acid anion 10:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78118 chebi_ph7_3 CHEBI:78117 biolink:ChemicalSubstance fatty acid anion 8:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78117 chebi_ph7_3 CHEBI:78116 biolink:ChemicalSubstance fatty acid anion 6:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78116 chebi_ph7_3 UBERON:0005389 biolink:AnatomicalEntity transparent eye structure A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array. go-plus.json lens http://purl.obolibrary.org/obo/UBERON_0005389 UBERON:0005388 biolink:AnatomicalEntity photoreceptor array An array of photoreceptors and any supporting cells found in an eye. go-plus.json light-sensitive tissue http://purl.obolibrary.org/obo/UBERON_0005388 CHEBI:78115 biolink:ChemicalSubstance fatty acid anion 4:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78115 chebi_ph7_3 UBERON:0005373 biolink:AnatomicalEntity spinal cord dorsal column the wedge-shaped fiber bundle of white matter in the dorsomedial side of the spinal cord that is made up of the fasciculus gracilis and fasciculus cuneatus; it is part of the ascending posterior column-medial lemniscus pathway that is important for well-localized fine touch and conscious proprioception go-plus.json posterior column|dorsal columns|dorsal column system|dorsal column of spinal cord|spinal cord posterior column|dorsal column http://purl.obolibrary.org/obo/UBERON_0005373 CHEBI:78121 biolink:ChemicalSubstance fatty acid anion 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78121 chebi_ph7_3 CHEBI:78125 biolink:ChemicalSubstance fatty acid anion 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78125 chebi_ph7_3 CHEBI:78124 biolink:ChemicalSubstance fatty acid anion 17:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78124 chebi_ph7_3 CHEBI:78123 biolink:ChemicalSubstance fatty acid anion 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78123 chebi_ph7_3 CHEBI:78122 biolink:ChemicalSubstance fatty acid anion 15:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78122 chebi_ph7_3 CHEBI:78129 biolink:ChemicalSubstance fatty acid anion 26:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78129 chebi_ph7_3 CHEBI:78128 biolink:ChemicalSubstance fatty acid anion 24:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78128 chebi_ph7_3 CHEBI:78127 biolink:ChemicalSubstance fatty acid anion 22:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78127 chebi_ph7_3 CHEBI:78126 biolink:ChemicalSubstance fatty acid anion 20:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78126 chebi_ph7_3 CHEBI:20750 biolink:ChemicalSubstance 6-phospho-2-dehydro-D-gluconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_20750 chebi_ph7_3 UBERON:0005362 biolink:AnatomicalEntity vagus X ganglion the group of sensory neuron cell bodies associated with the vagus nerve go-plus.json vagus X|ganglion of vagus nerve|vagus neural ganglion|vagal ganglion|gX|right glossopharyngeal ganglion|vagus ganglion http://purl.obolibrary.org/obo/UBERON_0005362 CHEBI:78131 biolink:ChemicalSubstance fatty acid anion 30:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78131 chebi_ph7_3 CHEBI:78130 biolink:ChemicalSubstance fatty acid anion 28:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78130 chebi_ph7_3 CHEBI:78136 biolink:ChemicalSubstance fatty alcohol 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78136 chebi_ph7_3 CHEBI:78135 biolink:ChemicalSubstance 1-pentadecylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78135 CHEBI:19775 biolink:ChemicalSubstance quinaldate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19775 chebi_ph7_3 CHEBI:78133 biolink:ChemicalSubstance fatty alcohol 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78133 chebi_ph7_3 CHEBI:78139 biolink:ChemicalSubstance fatty alcohol 20:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78139 chebi_ph7_3 UBERON:0005367 biolink:AnatomicalEntity hippocampus granule cell layer go-plus.json hippocampus granular layer http://purl.obolibrary.org/obo/UBERON_0005367 CHEBI:78138 biolink:ChemicalSubstance fatty alcohol 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78138 chebi_ph7_3 UBERON:0005366 biolink:AnatomicalEntity olfactory lobe The lobe at the anterior part of each cerebral hemisphere, responsible for olfactory functions. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005366 GO:0018528 biolink:MolecularActivity iminodiacetate dehydrogenase activity Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine. UM-BBD_reactionID:r0589 go-plus.json http://purl.obolibrary.org/obo/GO_0018528 GO:0018527 biolink:MolecularActivity cyclohexylamine oxidase activity Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide. UM-BBD_reactionID:r0754|EC:1.4.3.12|RHEA:18433|MetaCyc:CYCLOHEXYLAMINE-OXIDASE-RXN go-plus.json cyclohexylamine:oxygen oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0018527 GO:0018529 biolink:MolecularActivity nitrilotriacetate monooxygenase activity Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate. EC:1.14.14.10|UM-BBD_reactionID:r0587 go-plus.json http://purl.obolibrary.org/obo/GO_0018529 GO:0018524 biolink:MolecularActivity acetophenone carboxylase activity Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate. UM-BBD_reactionID:r0033|EC:6.4.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018524 GO:0018523 biolink:MolecularActivity quinoline 2-oxidoreductase activity Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor. RHEA:17749|UM-BBD_reactionID:r0045|MetaCyc:1.3.99.17-RXN|EC:1.3.99.17 go-plus.json quinoline:acceptor 2-oxidoreductase (hydroxylating) http://purl.obolibrary.org/obo/GO_0018523 GO:0018526 biolink:MolecularActivity 2-aminobenzoyl-CoA reductase activity Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA. UM-BBD_reactionID:r0342 go-plus.json http://purl.obolibrary.org/obo/GO_0018526 GO:0018525 biolink:MolecularActivity 4-hydroxybenzoyl-CoA reductase activity Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin. MetaCyc:OHBENZCOARED-RXN|UM-BBD_reactionID:r0158|KEGG_REACTION:R05316|RHEA:29603|EC:1.1.7.1 go-plus.json 4-hydroxybenzoyl-coA reductase (dehydroxylating) activity|4-hydroxybenzoyl-coA:(acceptor) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018525 GO:0018520 biolink:MolecularActivity cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2. EC:1.3.1.67|UM-BBD_reactionID:r0179|MetaCyc:1.3.1.67-RXN go-plus.json cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)|4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018520 CHEBI:138980 biolink:ChemicalSubstance AZD1979(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138980 chebi_ph7_3 GO:0018522 biolink:MolecularActivity benzoyl-CoA reductase activity Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin. EC:1.3.7.8|RHEA:30199|KEGG_REACTION:R02451|UM-BBD_reactionID:r0190|MetaCyc:1.3.99.15-RXN go-plus.json cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming) activity|benzoyl-CoA reductase (dearomatizing) activity http://purl.obolibrary.org/obo/GO_0018522 GO:0018521 biolink:MolecularActivity 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH. EC:1.3.1.68|UM-BBD_reactionID:r0224|RHEA:15657|KEGG_REACTION:R05314|MetaCyc:1.3.1.68-RXN go-plus.json 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0018521 GO:0018538 biolink:MolecularActivity epoxide carboxylase activity Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+. go-plus.json http://purl.obolibrary.org/obo/GO_0018538 GO:0018535 biolink:MolecularActivity nicotine dehydrogenase activity Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor. MetaCyc:NICOTINE-DEHYDROGENASE-RXN|UM-BBD_enzymeID:e0337|EC:1.5.99.4|RHEA:14769 go-plus.json nicotine:acceptor 6-oxidoreductase (hydroxylating)|nicotine oxidase activity|nicotine:(acceptor) 6-oxidoreductase (hydroxylating)|D-nicotine oxidase activity http://purl.obolibrary.org/obo/GO_0018535 GO:0018534 biolink:MolecularActivity nitrilotriacetate dehydrogenase activity Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate. UM-BBD_reactionID:r0588|EC:1.5.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0018534 GO:0018537 biolink:MolecularActivity coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. RHEA:21144|KEGG_REACTION:R04464|EC:1.5.98.2|MetaCyc:METHELENE-THMPT-OXI-RXN|UM-BBD_reactionID:r0354 go-plus.json 5,10-methylenetetrahydromethanopterin cyclohydrolase activity|5,10-methylenetetrahydromethanopterin reductase activity|methylenetetrahydromethanopterin reductase activity|5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|N(5),N(10)-methylenetetrahydromethanopterin reductase activity|N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|methylene-H(4)MPT reductase activity|methylene-H4MPT reductase activity|N5,N10-methylenetetrahydromethanopterin reductase activity|N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity http://purl.obolibrary.org/obo/GO_0018537 GO:0018536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018536 GO:0018531 biolink:MolecularActivity (S)-6-hydroxynicotine oxidase activity Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2). RHEA:11880|EC:1.5.3.5|MetaCyc:S-6-HYDROXYNICOTINE-OXIDASE-RXN|UM-BBD_reactionID:r0478|KEGG_REACTION:R03202 go-plus.json (S)-6-hydroxynicotine:oxygen oxidoreductase activity|6-hydroxy-L-nicotine oxidase activity|L-6-hydroxynicotine oxidase activity|6-hydroxy-L-nicotine:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018531 GO:0018530 biolink:MolecularActivity (R)-6-hydroxynicotine oxidase activity Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2). RHEA:10012|EC:1.5.3.6|KEGG_REACTION:R07170|MetaCyc:R-6-HYDROXYNICOTINE-OXIDASE-RXN|UM-BBD_reactionID:r0477 go-plus.json D-6-hydroxynicotine oxidase activity|(R)-6-hydroxynicotine:oxygen oxidoreductase activity|6-hydroxy-D-nicotine oxidase activity http://purl.obolibrary.org/obo/GO_0018530 GO:0018533 biolink:BiologicalProcess peptidyl-cysteine acetylation The acetylation of peptidyl-cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0018533 GO:0018532 biolink:MolecularActivity 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin. EC:1.5.99.-|UM-BBD_reactionID:r0353 go-plus.json coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|coenzyme F420-independent methylene-H4MPT dehydrogenase activity|F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|F420-independent methylene-H4MPT dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018532 NCBITaxon:665079 biolink:OrganismalEntity Sclerotinia sclerotiorum 1980 UF-70 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_665079 CHEBI:29198 biolink:ChemicalSubstance phosphinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29198 chebi_ph7_3 GO:0018509 biolink:MolecularActivity cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+. MetaCyc:1.3.1.56-RXN|RHEA:17033|UM-BBD_enzymeID:e0134|EC:1.3.1.56 go-plus.json 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity|biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity|cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018509 GO:0018506 biolink:MolecularActivity maleylacetate reductase activity Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+. MetaCyc:MALEYLACETATE-REDUCTASE-RXN|UM-BBD_enzymeID:e0063|EC:1.3.1.32 go-plus.json 3-oxoadipate:NAD(P)+ oxidoreductase activity|maleolylacetate reductase activity http://purl.obolibrary.org/obo/GO_0018506 CHEBI:138966 biolink:ChemicalSubstance 9beta-pimara-7,15-diene-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138966 chebi_ph7_3 GO:0018505 biolink:MolecularActivity cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+. EC:1.3.1.29|UM-BBD_enzymeID:e0122|RHEA:11832|MetaCyc:1.3.1.29-RXN go-plus.json (+)-cis-naphthalene dihydrodiol dehydrogenase activity|cis-dihydrodiol naphthalene dehydrogenase activity|cis-naphthalene dihydrodiol dehydrogenase activity|naphthalene dihydrodiol dehydrogenase activity|1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity|cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018505 CHEBI:138965 biolink:ChemicalSubstance 11,20-dihydroxyferruginol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138965 chebi_ph7_3 GO:0018508 biolink:MolecularActivity cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+. UM-BBD_enzymeID:e0219 go-plus.json benzoate cis-diol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018508 CHEBI:138964 biolink:ChemicalSubstance 2-hydroxyisovaleryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138964 GO:0018507 biolink:MolecularActivity cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol. KEGG_REACTION:R04151|RHEA:16253|EC:1.3.1.49|UM-BBD_reactionID:r0488|MetaCyc:1.3.1.49-RXN go-plus.json (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity|cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018507 CHEBI:138963 biolink:ChemicalSubstance 11,20-dihydroxysugiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138963 chebi_ph7_3 GO:0018502 biolink:MolecularActivity 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone. MetaCyc:LINC-RXN|UM-BBD_reactionID:r0553|RHEA:15741 go-plus.json http://purl.obolibrary.org/obo/GO_0018502 GO:0018501 biolink:MolecularActivity cis-chlorobenzene dihydrodiol dehydrogenase activity Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol. UM-BBD_enzymeID:e0411 go-plus.json http://purl.obolibrary.org/obo/GO_0018501 CHEBI:138969 biolink:ChemicalSubstance ent-cassa-12,15-dien-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138969 chebi_ph7_3 CHEBI:138968 biolink:ChemicalSubstance ent-cassa-12,15-dien-2beta,3beta-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138968 chebi_ph7_3 GO:0018504 biolink:MolecularActivity cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+. EC:1.3.1.19|UM-BBD_enzymeID:e0060|MetaCyc:1.3.1.19-RXN|RHEA:15457 go-plus.json cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity|cis-benzene glycol dehydrogenase activity|cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018504 GO:0018503 biolink:MolecularActivity trans-1,2-dihydrodiolphenanthrene dehydrogenase activity Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene. UM-BBD_reactionID:r0574 go-plus.json http://purl.obolibrary.org/obo/GO_0018503 CHEBI:138967 biolink:ChemicalSubstance ent-cassa-12,15-dien-2beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138967 chebi_ph7_3 GO:0018500 biolink:MolecularActivity trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene. UM-BBD_reactionID:r0575 go-plus.json http://purl.obolibrary.org/obo/GO_0018500 CHEBI:138962 biolink:ChemicalSubstance 11-hydroxysugiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138962 chebi_ph7_3 CHEBI:138961 biolink:ChemicalSubstance sugiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138961 chebi_ph7_3 GO:0018517 biolink:MolecularActivity phthalate 4,5-cis-dihydrodiol dehydrogenase activity Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH. EC:1.3.1.64|UM-BBD_reactionID:r0142|KEGG_REACTION:R05275|MetaCyc:1.3.1.64-RXN|RHEA:13837 go-plus.json cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018517 CHEBI:138977 biolink:ChemicalSubstance quorum sensing inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_138977 GO:0018516 biolink:MolecularActivity 2,4-dichlorobenzoyl-CoA reductase activity Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH. KEGG_REACTION:R05276|RHEA:23076|MetaCyc:1.3.1.63-RXN|EC:1.21.1.2|UM-BBD_reactionID:r0138 go-plus.json 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating) http://purl.obolibrary.org/obo/GO_0018516 GO:0018519 biolink:MolecularActivity cis-dihydroethylcatechol dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH. EC:1.3.1.66|KEGG_REACTION:R05313|RHEA:18101|MetaCyc:1.3.1.66-RXN|UM-BBD_reactionID:r0309 go-plus.json cis-ethylbenzene glycol dehydrogenase activity|cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018519 CHEBI:138975 biolink:ChemicalSubstance mogroside IE go-plus.json http://purl.obolibrary.org/obo/CHEBI_138975 chebi_ph7_3 GO:0018518 biolink:MolecularActivity 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH. EC:1.3.1.65|RHEA:24556|UM-BBD_reactionID:r0053|KEGG_REACTION:R05312|MetaCyc:RXN-643 go-plus.json 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity|5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase http://purl.obolibrary.org/obo/GO_0018518 CHEBI:138974 biolink:ChemicalSubstance mogrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138974 chebi_ph7_3 GO:0018513 biolink:MolecularActivity dibenzothiophene dihydrodiol dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH. EC:1.3.1.60|UM-BBD_reactionID:r0161|RHEA:24188|KEGG_REACTION:R05310|MetaCyc:1.3.1.60-RXN go-plus.json cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018513 GO:0018512 biolink:MolecularActivity obsolete 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+. UM-BBD_reactionID:r0216 go-plus.json 1,2-dihydroxy-3-methylcyclohexa-3,5-diene-carboxylate dehydrogenase activity|1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0018512 GO:0018515 biolink:MolecularActivity pimeloyl-CoA dehydrogenase activity Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH. EC:1.3.1.62|UM-BBD_reactionID:r0194|KEGG_REACTION:R05311|RHEA:19665|MetaCyc:1.3.1.62-RXN go-plus.json pimeloyl-CoA:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018515 CHEBI:138979 biolink:ChemicalSubstance hemisuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138979 GO:0018514 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018514 GO:0018511 biolink:MolecularActivity 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH. UM-BBD_reactionID:r0396|RHEA:23772|KEGG_REACTION:R05240|MetaCyc:RXN-665|EC:1.3.1.58 go-plus.json cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018511 GO:0018510 biolink:MolecularActivity phloroglucinol reductase activity Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol. RHEA:10080|EC:1.3.1.57|UM-BBD_reactionID:r0007|KEGG_REACTION:R05308|MetaCyc:R5-RXN go-plus.json dihydrophloroglucinol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018510 CHEBI:138973 biolink:ChemicalSubstance 11-oxocucurbitadienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138973 chebi_ph7_3 CHEBI:138972 biolink:ChemicalSubstance 11alpha-hydroxycucurbitadienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138972 chebi_ph7_3 CHEBI:138971 biolink:ChemicalSubstance drimendiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138971 chebi_ph7_3 CHEBI:138970 biolink:ChemicalSubstance ent-3beta-hydroxycassa-12,15-dien-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_138970 chebi_ph7_3 OBO:GOREL_0002008 biolink:OntologyClass obsolete has intermediate GOREL:0002008 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002008 UBERON:0005309 biolink:AnatomicalEntity pronephric nephron A pronephric nephron is the functional unit of the pronephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005309 UBERON:0005308 biolink:AnatomicalEntity nephrostome The nephrostome is the opening of the pronephros into the body cavity[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005308 OBO:GOREL_0002001 biolink:OntologyClass obsolete results_in_assembly_of GOREL:0002001 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002001 CHEBI:29179 biolink:ChemicalSubstance tRNA(Ser) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29179 OBO:GOREL_0002003 biolink:OntologyClass results_in_distribution_of GOREL:0002003 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002003 OBO:GOREL_0002002 biolink:OntologyClass obsolete results_in_disassembly_of GOREL:0002002 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002002 OBO:GOREL_0002005 biolink:OntologyClass results_in_fusion_of GOREL:0002005 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002005 CHEBI:29176 biolink:ChemicalSubstance tRNA(Gly) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29176 OBO:GOREL_0002004 biolink:OntologyClass results_in_fission_of GOREL:0002004 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002004 CHEBI:29175 biolink:ChemicalSubstance tRNA(Glu) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29175 OBO:GOREL_0002007 biolink:OntologyClass obsolete results_in_remodeling_of GOREL:0002007 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002007 CHEBI:29178 biolink:ChemicalSubstance tRNA(His) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29178 OBO:GOREL_0002006 biolink:OntologyClass obsolete results_in_organization_of GOREL:0002006 go-plus.json http://purl.obolibrary.org/obo/GOREL_0002006 CHEBI:29177 biolink:ChemicalSubstance tRNA(Pro) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29177 CHEBI:138944 biolink:ChemicalSubstance salviol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138944 chebi_ph7_3 UBERON:0005310 biolink:AnatomicalEntity pronephric nephron tubule The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]. go-plus.json pronephric tubule|ciliated neck segment http://purl.obolibrary.org/obo/UBERON_0005310 CHEBI:29183 biolink:ChemicalSubstance tRNA(Val) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29183 CHEBI:29182 biolink:ChemicalSubstance tRNA(Tyr) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29182 CHEBI:138943 biolink:ChemicalSubstance carnosate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138943 chebi_ph7_3 CHEBI:29185 biolink:ChemicalSubstance tRNA(Lys) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29185 CHEBI:138942 biolink:ChemicalSubstance 11-hydroxyferruginol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138942 chebi_ph7_3 CHEBI:29184 biolink:ChemicalSubstance tRNA(Phe) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29184 CHEBI:138941 biolink:ChemicalSubstance 2-hydroxyoctanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138941 CHEBI:138948 biolink:ChemicalSubstance (4S)-2,3-dehydroleucocyanidin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138948 chebi_ph7_3 CHEBI:29181 biolink:ChemicalSubstance tRNA(Trp) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29181 CHEBI:138946 biolink:ChemicalSubstance cochalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138946 chebi_ph7_3 CHEBI:138945 biolink:ChemicalSubstance maniladiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138945 chebi_ph7_3 CHEBI:29180 biolink:ChemicalSubstance tRNA(Thr) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29180 UBERON:0005317 biolink:AnatomicalEntity pulmonary artery endothelium An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]. go-plus.json pulmonary artery endothelial tube http://purl.obolibrary.org/obo/UBERON_0005317 UBERON:0005316 biolink:AnatomicalEntity endocardial endothelium The endothelial lining of the endocardium. go-plus.json endothelium of endocardium|endocardium endothelium http://purl.obolibrary.org/obo/UBERON_0005316 CHEBI:30166 biolink:ChemicalSubstance boride(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30166 UBERON:0005315 biolink:AnatomicalEntity alveolar secondary septum A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005315 UBERON:0005314 biolink:AnatomicalEntity alveolar primary septum A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005314 CHEBI:138940 biolink:ChemicalSubstance 1-O-hexadecyl-2-(8-carboxyoctanoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138940 UBERON:0005313 biolink:AnatomicalEntity mammary duct terminal end bud A unique club-shaped epithelial structure that develops at the tip of the mammary duct at the onset of puberty under the action of circulating hormones. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005313 CHEBI:30164 biolink:ChemicalSubstance 5-diphospho-1D-myo-inositol pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30164 UBERON:0005312 biolink:AnatomicalEntity primary ureteric bud . go-plus.json http://purl.obolibrary.org/obo/UBERON_0005312 UBERON:0005311 biolink:AnatomicalEntity mammary placode The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper[GO]. go-plus.json mammary anlage http://purl.obolibrary.org/obo/UBERON_0005311 NCBITaxon:2704647 biolink:OrganismalEntity Metakinetoplastina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2704647 CHEBI:29186 biolink:ChemicalSubstance tRNA(Asp) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29186 CHEBI:138955 biolink:ChemicalSubstance daturadiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138955 chebi_ph7_3 CHEBI:29195 biolink:ChemicalSubstance cyanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29195 chebi_ph7_3 CHEBI:138959 biolink:ChemicalSubstance 2-hydroxydecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_138959 CHEBI:29192 biolink:ChemicalSubstance hydrogenperoxide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29192 UBERON:0005307 biolink:AnatomicalEntity chorion-containing eggshell An eggshell that contains chorion. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005307 CHEBI:138951 biolink:ChemicalSubstance 3'-hydroxy-5'-unsubstituted flavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_138951 chebi_ph7_3 CHEBI:138950 biolink:ChemicalSubstance (4S)-2,3-dehydroleucopelargonidin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138950 chebi_ph7_3 CHEBI:29158 biolink:ChemicalSubstance Asp-tRNA(Asp) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29158 CHEBI:29157 biolink:ChemicalSubstance Glu-tRNA(Glu) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29157 CHEBI:138929 biolink:ChemicalSubstance N-hexadecanoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138929 CHEBI:29159 biolink:ChemicalSubstance Trp-tRNA(Trp) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29159 CHEBI:29154 biolink:ChemicalSubstance Pro-tRNA(Pro) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29154 CHEBI:29153 biolink:ChemicalSubstance Phe-tRNA(Phe) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29153 CHEBI:29156 biolink:ChemicalSubstance Gly-tRNA(Gly) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29156 CHEBI:29155 biolink:ChemicalSubstance His-tRNA(His) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29155 CHEBI:29161 biolink:ChemicalSubstance Tyr-tRNA(Tyr) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29161 CHEBI:138922 biolink:ChemicalSubstance 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138922 CHEBI:29160 biolink:ChemicalSubstance Ile-tRNA(Ile) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29160 CHEBI:29163 biolink:ChemicalSubstance Thr-tRNA(Thr) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29163 CHEBI:29162 biolink:ChemicalSubstance Ser-tRNA(Ser) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29162 CHEBI:138926 biolink:ChemicalSubstance 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138926 CHEBI:138923 biolink:ChemicalSubstance 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138923 CHEBI:44788 biolink:ChemicalSubstance 2-succinylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44788 CHEBI:29169 biolink:ChemicalSubstance tRNA(Leu) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29169 CHEBI:29168 biolink:ChemicalSubstance tRNA(Gln) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29168 CHEBI:138938 biolink:ChemicalSubstance EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_138938 CHEBI:44785 biolink:ChemicalSubstance peroxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_44785 CHEBI:29164 biolink:ChemicalSubstance Val-tRNA(Val) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29164 CHEBI:29167 biolink:ChemicalSubstance tRNA(Cys) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29167 CHEBI:29166 biolink:ChemicalSubstance Gln-tRNA(Gln) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29166 CHEBI:29172 biolink:ChemicalSubstance tRNA(Asn) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29172 CHEBI:29171 biolink:ChemicalSubstance tRNA(Arg) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29171 CHEBI:29174 biolink:ChemicalSubstance tRNA(Ile) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29174 CHEBI:29173 biolink:ChemicalSubstance tRNA(Met) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29173 CHEBI:138930 biolink:ChemicalSubstance N-oleoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138930 CHEBI:138937 biolink:ChemicalSubstance D-xylulose 1,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138937 CHEBI:138936 biolink:ChemicalSubstance N(6)-hexadecanoyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138936 chebi_ph7_3 CHEBI:29170 biolink:ChemicalSubstance tRNA(Ala) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29170 CHEBI:138934 biolink:ChemicalSubstance N-(4-oxoglutaryl)-L-cysteinylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138934 CHEBI:30156 biolink:ChemicalSubstance 6,7-dihydropteridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30156 chebi_ph7_3 CHEBI:30154 biolink:ChemicalSubstance 5beta-pregnane-3,20-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_30154 chebi_ph7_3 GO:0043690 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043690 GO:0004088 biolink:MolecularActivity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate. Reactome:R-HSA-73577|EC:6.3.5.5|RHEA:18633|MetaCyc:CARBPSYN-RXN go-plus.json glutamine-dependent carbamoyl-phosphate synthase activity|GD-CPSase activity|carbamyl phosphate synthetase (glutamine) activity|glutamine-dependent carbamyl phosphate synthetase activity|carbamoyl-phosphate synthase (glutamine-hydrolysing) activity|hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity|carbamoyl phosphate synthetase activity|CPS activity|carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity|carbamoylphosphate synthetase II activity|carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity|carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity|carbamoyl phosphate synthase (glutamine-hydrolyzing) activity http://purl.obolibrary.org/obo/GO_0004088 GO:0043696 biolink:BiologicalProcess dedifferentiation The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors. Wikipedia:Cellular_differentiation#Dedifferentiation go-plus.json http://purl.obolibrary.org/obo/GO_0043696 GO:0004087 biolink:MolecularActivity carbamoyl-phosphate synthase (ammonia) activity Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate. RHEA:10624|KEGG_REACTION:R00149|EC:6.3.4.16|MetaCyc:6.3.4.16-RXN|Reactome:R-HSA-70555 go-plus.json carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)|carbamoylphosphate synthase activity|CPS I activity|carbamoyl-phosphate synthetase (ammonia) activity|carbamoyl phosphate synthase (ammonia) activity|carbamoylphosphate synthetase (ammonia) activity|carbmoylphosphate synthetase activity|carbon-dioxide--ammonia ligase activity|carbamylphosphate synthetase I|carbamoylphosphate synthase (ammonia)|carbamylphosphate synthetase activity|carbamoyl-phosphate synthetase I activity http://purl.obolibrary.org/obo/GO_0004087 GO:0043695 biolink:BiologicalProcess detection of pheromone The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0043695 GO:0043698 biolink:CellularComponent iridosome A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance. go-plus.json reflecting platelet http://purl.obolibrary.org/obo/GO_0043698 GO:0004089 biolink:MolecularActivity carbonate dehydratase activity Catalysis of the reaction: H2CO3 = CO2 + H2O. Reactome:R-HSA-1237045|Reactome:R-HSA-1475028|Reactome:R-HSA-1475032|Reactome:R-HSA-1475017|Reactome:R-HSA-1475025|EC:4.2.1.1|MetaCyc:CARBODEHYDRAT-RXN|Reactome:R-HSA-1475435|Reactome:R-HSA-1237047|Reactome:R-HSA-1475436|Reactome:R-HSA-1237059|Reactome:R-HSA-1475022|RHEA:10748|Reactome:R-HSA-1475026|Reactome:R-HSA-1237081 go-plus.json carbonic dehydratase activity|anhydrase activity|carbonate hydro-lyase (carbon-dioxide-forming)|carbonate anhydrase activity|carbonate hydro-lyase activity|carbonic anhydrase activity|carbonic acid anhydrase activity|carbonic anhydrase A|carboxyanhydrase activity http://purl.obolibrary.org/obo/GO_0004089 GO:0043697 biolink:BiologicalProcess cell dedifferentiation The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. go-plus.json http://purl.obolibrary.org/obo/GO_0043697 GO:0004084 biolink:MolecularActivity branched-chain-amino-acid transaminase activity Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid. Reactome:R-HSA-70724|Reactome:R-HSA-70723|EC:2.6.1.42|Reactome:R-HSA-508179|Reactome:R-HSA-508189 go-plus.json branched-chain amino acid aminotransferase activity|branched-chain-amino-acid:2-oxoglutarate aminotransferase activity|L-branched chain amino acid aminotransferase activity|branched-chain aminotransferase activity|glutamate-branched-chain amino acid transaminase activity|branched-chain amino acid-glutamate transaminase activity|transaminase B activity http://purl.obolibrary.org/obo/GO_0004084 GO:0043692 biolink:BiologicalProcess monoterpene metabolic process The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure. go-plus.json monoterpene metabolism http://purl.obolibrary.org/obo/GO_0043692 GO:0004083 biolink:MolecularActivity bisphosphoglycerate 2-phosphatase activity Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate. MetaCyc:BISPHOSPHOGLYCERATE-PHOSPHATASE-RXN|RHEA:21904|KEGG_REACTION:R01516 go-plus.json 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0004083 GO:0043691 biolink:BiologicalProcess reverse cholesterol transport The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0043691 GO:0004086 biolink:MolecularActivity obsolete carbamoyl-phosphate synthase activity OBSOLETE. Catalysis of a reaction that results in the formation of carbamoyl phosphate. go-plus.json carbamoyl-phosphate synthase activity|carbamoyl phosphate synthase activity http://purl.obolibrary.org/obo/GO_0004086 GO:0043694 biolink:BiologicalProcess monoterpene catabolic process The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure. go-plus.json monoterpene catabolism http://purl.obolibrary.org/obo/GO_0043694 GO:0004085 biolink:MolecularActivity butyryl-CoA dehydrogenase activity Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein. UM-BBD_reactionID:r0013|KEGG_REACTION:R01178|EC:1.3.8.1|MetaCyc:BUTYRYL-COA-DEHYDROGENASE-RXN go-plus.json short-chain acyl-coenzyme A dehydrogenase activity|short-chain-acyl-CoA dehydrogenase activity|short-chain acyl CoA dehydrogenase activity|ethylene reductase activity|unsaturated acyl coenzyme A reductase activity|butyryl coenzyme A dehydrogenase activity|butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity|butanoyl-CoA:acceptor 2,3-oxidoreductase activity|3-hydroxyacyl CoA reductase activity|enoyl-coenzyme A reductase activity|butyryl dehydrogenase activity|unsaturated acyl-CoA reductase activity http://purl.obolibrary.org/obo/GO_0004085 GO:0043693 biolink:BiologicalProcess monoterpene biosynthetic process The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure. go-plus.json monoterpene biosynthesis http://purl.obolibrary.org/obo/GO_0043693 GO:0004091 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004091 GO:0004090 biolink:MolecularActivity carbonyl reductase (NADPH) activity Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+. EC:1.1.1.184|MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN|Reactome:R-HSA-8937419|RHEA:19257 go-plus.json aldehyde reductase I activity|secondary-alcohol:NADP+ oxidoreductase activity|xenobiotic ketone reductase activity|prostaglandin 9-ketoreductase activity|carbonyl reductase activity|aldehyde reductase 1|NADPH-dependent carbonyl reductase activity|NADPH2-dependent carbonyl reductase activity|ALR3|nonspecific NADPH-dependent carbonyl reductase activity http://purl.obolibrary.org/obo/GO_0004090 GO:0004093 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004093 GO:0004092 biolink:MolecularActivity carnitine O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA. MetaCyc:CARNITINE-O-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-390284|Reactome:R-HSA-390291|RHEA:21136|KEGG_REACTION:R02396|EC:2.3.1.7 go-plus.json acetylcarnitine transferase activity|carnitine acetyltransferase activity|carnitine O-acetyltransferase II activity|acetyl-CoA-carnitine O-acetyltransferase activity|CATC|carnitine-acetyl-CoA transferase activity|carnitine acetylase activity|carnitine O-acetyltransferase I activity|carnitine acetyl coenzyme A transferase activity|acetyl-CoA:carnitine O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004092 GO:0043699 biolink:CellularComponent leucosome A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast. go-plus.json refractosome http://purl.obolibrary.org/obo/GO_0043699 GO:0004099 biolink:MolecularActivity chitin deacetylase activity Catalysis of the reaction: chitin + H2O = chitosan + acetate. RHEA:10464|EC:3.5.1.41|MetaCyc:CHITIN-DEACETYLASE-RXN go-plus.json chitin amidohydrolase activity http://purl.obolibrary.org/obo/GO_0004099 GO:0004098 biolink:MolecularActivity cerebroside-sulfatase activity Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate. EC:3.1.6.8|RHEA:21300|Reactome:R-HSA-1606807|MetaCyc:CEREBROSIDE-SULFATASE-RXN go-plus.json cerebroside sulfate sulfatase activity|arylsulfatase A activity|cerebroside-sulphatase activity|cerebroside-3-sulfate 3-sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0004098 PR:000029394 biolink:Protein ATP-dependent RNA helicase DDX58 A protein that is a translation product of the human DDX58 gene or a 1:1 ortholog thereof. go-plus.json retinoic acid-inducible gene 1 protein|RLR-1|DDX58|RIG-I-like receptor 1|retinoic acid-inducible gene I protein|RIG-1|DEAD box protein 58|RIG-I http://purl.obolibrary.org/obo/PR_000029394 GO:0004095 biolink:MolecularActivity carnitine O-palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine. EC:2.3.1.21|Reactome:R-HSA-200410|RHEA:12661|Reactome:R-HSA-200406|MetaCyc:CARNITINE-O-PALMITOYLTRANSFERASE-RXN go-plus.json CPTi|acylcarnitine transferase activity|CPT-B|carnitine palmitoyltransferase-A|CPT-A|palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity|carnitine palmitoyltransferase II|outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity|carnitine palmitoyltransferase I|palmitoylcarnitine transferase activity|CPT I (outer membrane carnitine palmitoyl transferase)|CPTo|CPT|carnitine palmitoyltransferase activity|L-carnitine palmitoyltransferase activity http://purl.obolibrary.org/obo/GO_0004095 GO:0004094 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004094 GO:0004097 biolink:MolecularActivity catechol oxidase activity Catalysis of the reaction: 2 L-dopa + O2 = 2 H2O + 2 L-dopaquinone. This reaction catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones. MetaCyc:RXN-13061|RHEA:21632|MetaCyc:CATECHOL-OXIDASE-RXN|EC:1.10.3.1 go-plus.json phenolase activity|pyrocatechol oxidase|tyrosinase activity|dopamine monooxygenase activity|catecholase|o-diphenol oxidoreductase|o-diphenolase activity|diphenol oxidase activity|L-dopa oxidase activity|L-DOPA monooxygenase activity|polyphenol oxidase activity http://purl.obolibrary.org/obo/GO_0004097 GO:0004096 biolink:MolecularActivity catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. UM-BBD_enzymeID:e0834|Reactome:R-HSA-76031|RHEA:20309|Reactome:R-HSA-1222704|MetaCyc:CATAL-RXN|EC:1.11.1.6 go-plus.json CAT|manganese catalase activity|heme catalase activity|catalase reaction|optidase activity|equilase activity|bacterial catalase-peroxidase activity|hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|catalase-peroxidase activity|caperase activity|haem catalase activity http://purl.obolibrary.org/obo/GO_0004096 GO:0004069 biolink:MolecularActivity L-aspartate:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate. RHEA:21824|MetaCyc:ASPAMINOTRANS-RXN|Reactome:R-HSA-70596|KEGG_REACTION:R00355|Reactome:R-HSA-70613|Reactome:R-HSA-70592|EC:2.6.1.1|Reactome:R-HSA-70581 go-plus.json L-aspartate-alpha-ketoglutarate transaminase activity|2-oxoglutarate-glutamate aminotransferase activity|oxaloacetate-aspartate aminotransferase activity|glutamate-oxalate transaminase activity|glutamate-oxalacetate aminotransferase activity|glutamic-aspartic aminotransferase activity|aspartate-2-oxoglutarate transaminase activity|aspartate:2-oxoglutarate aminotransferase activity|oxaloacetate transferase activity|L-aspartic aminotransferase activity|glutamic--aspartic transaminase activity|aspartate aminotransferase activity|aspartic aminotransferase activity|aspartic acid aminotransferase activity|aspartate alpha-ketoglutarate transaminase activity|aspartate transaminase activity|L-aspartate-2-oxoglutarate-transaminase activity|L-aspartate transaminase activity|glutamate oxaloacetate transaminase activity|glutamic oxalic transaminase activity|L-aspartate-2-oxoglutarate aminotransferase activity|glutamic-oxalacetic transaminase activity|aspartyl aminotransferase activity|AspT|GOT (enzyme)|transaminase A activity|AAT|L-aspartate-2-ketoglutarate aminotransferase activity|glutamic--oxaloacetic transaminase activity http://purl.obolibrary.org/obo/GO_0004069 GO:0004066 biolink:MolecularActivity asparagine synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate. RHEA:12228|EC:6.3.5.4|MetaCyc:ASNSYNB-RXN|Reactome:R-HSA-70599 go-plus.json AS|asparagine synthetase B activity|glutamine-dependent asparagine synthetase activity|asparagine synthase (glutamine-hydrolysing)|asparagine synthetase (glutamine-hydrolyzing) activity|L-aspartate:L-glutamine amido-ligase (AMP-forming)|AS-B activity|asparagine synthetase (glutamine-hydrolysing) http://purl.obolibrary.org/obo/GO_0004066 GO:0004065 biolink:MolecularActivity arylsulfatase activity Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate. EC:3.1.6.1|MetaCyc:ARYLSULFAT-RXN|RHEA:17261 go-plus.json aryl-sulphate sulphohydrolase activity|sulfatase activity|phenolsulfatase activity|arylsulfohydrolase activity|arylsulphatase activity|nitrocatechol sulfatase activity|phenylsulfatase activity|p-nitrophenyl sulfatase activity|estrogen sulfatase activity|4-methylumbelliferyl sulfatase activity|aryl-sulfate sulfohydrolase activity|aryl-sulfate sulphohydrolase activity http://purl.obolibrary.org/obo/GO_0004065 GO:0004068 biolink:MolecularActivity aspartate 1-decarboxylase activity Catalysis of the reaction: L-aspartate = beta-alanine + CO2. EC:4.1.1.11|MetaCyc:PWY-5155|RHEA:19497|MetaCyc:ASPDECARBOX-RXN go-plus.json L-aspartate 1-carboxy-lyase (beta-alanine-forming)|aspartic alpha-decarboxylase|L-aspartate alpha-decarboxylase activity|aspartate alpha-decarboxylase activity|L-aspartate 1-carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0004068 GO:0004067 biolink:MolecularActivity asparaginase activity Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3. RHEA:21016|MetaCyc:ASPARAGHYD-RXN|EC:3.5.1.1|Reactome:R-HSA-6797627 go-plus.json L-asparagine amidohydrolase activity|asparaginase II|alpha-asparaginase activity|crasnitin|colaspase activity|elspar|L-asparaginase activity|leunase activity http://purl.obolibrary.org/obo/GO_0004067 GO:0004062 biolink:MolecularActivity aryl sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate. Reactome:R-HSA-158468|Reactome:R-HSA-176646|Reactome:R-HSA-176585|Reactome:R-HSA-158860|EC:2.8.2.1|MetaCyc:ARYL-SULFOTRANSFERASE-RXN|RHEA:12164|Reactome:R-HSA-176474|Reactome:R-HSA-159358|Reactome:R-HSA-158849 go-plus.json 4-nitrocatechol sulfokinase activity|aryl sulphotransferase activity|dopamine sulfotransferase activity|2-naphtholsulfotransferase activity|1-naphthol phenol sulfotransferase activity|phenol sulfokinase activity|ritodrine sulfotransferase activity|sulfokinase activity|phenol sulfotransferase activity|3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity|arylsulfotransferase|p-nitrophenol sulfotransferase activity|PST http://purl.obolibrary.org/obo/GO_0004062 goslim_chembl GO:0004061 biolink:MolecularActivity arylformamidase activity Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine. RHEA:13009|MetaCyc:ARYLFORMAMIDASE-RXN|EC:3.5.1.9|Reactome:R-HSA-71189 go-plus.json formylase activity|formamidase I|formylkynureninase activity|kynurenine formamidase activity|formamidase II|formylkynurenine formamidase activity|aryl-formylamine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0004061 GO:0004064 biolink:MolecularActivity arylesterase activity Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate. MetaCyc:ARYLESTERASE-RXN|RHEA:17309|EC:3.1.1.2|UM-BBD_reactionID:r0757 go-plus.json paraoxonase activity|A-esterase activity|aromatic esterase|aryl-ester hydrolase http://purl.obolibrary.org/obo/GO_0004064 GO:0004063 biolink:MolecularActivity aryldialkylphosphatase activity Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol. MetaCyc:ARYLDIALKYLPHOSPHATASE-RXN|EC:3.1.8.1|RHEA:18053|UM-BBD_enzymeID:e0054 go-plus.json esterase B1|esterase E4|organophosphorus acid anhydrase activity|phosphotriesterase activity|aryltriphosphatase activity|paraoxon hydrolase activity|aryltriphosphate dialkylphosphohydrolase activity|organophosphate hydrolase activity|OPH|paraoxonase activity|organophosphate esterase activity|A-esterase activity|pirimiphos-methyloxon esterase activity|paraoxon esterase activity|organophosphorus hydrolase activity http://purl.obolibrary.org/obo/GO_0004063 GO:0004071 biolink:MolecularActivity aspartate-ammonia ligase activity Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. MetaCyc:ASNSYNA-RXN|RHEA:11372|EC:6.3.1.1 go-plus.json L-asparagine synthetase activity|asparagine synthetase activity|L-aspartate:ammonia ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0004071 GO:0004070 biolink:MolecularActivity aspartate carbamoyltransferase activity Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate. Reactome:R-HSA-73573|RHEA:20013|KEGG_REACTION:R01397|MetaCyc:ASPCARBTRANS-RXN|EC:2.1.3.2 go-plus.json aspartic carbamyltransferase activity|L-aspartate transcarbamoylase activity|aspartic transcarbamylase activity|aspartate transcarbamoylase activity|ATCase activity|aspartate carbamyltransferase activity|carbamoylaspartotranskinase activity|carbamylaspartotranskinase activity|aspartic acid transcarbamoylase activity|aspartate transcarbamylase activity|L-aspartate transcarbamylase activity|carbamoyl-phosphate:L-aspartate carbamoyltransferase activity http://purl.obolibrary.org/obo/GO_0004070 GO:0004077 biolink:MolecularActivity biotin-[acetyl-CoA-carboxylase] ligase activity Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)). MetaCyc:BIOTINLIG-RXN|RHEA:11756|EC:6.3.4.15 go-plus.json biotin holoenzyme synthetase activity|acetyl CoA holocarboxylase synthetase activity|biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-acetyl coenzyme A carboxylase synthetase activity|biotin:apocarboxylase ligase activity|HCS|biotin--protein ligase activity|acetyl-CoA carboxylase biotin holoenzyme synthetase activity|biotin-acetyl-CoA carboxylase synthetase|acetyl coenzyme A holocarboxylase synthetase activity|biotin-acetyl-CoA-carboxylase ligase activity|biotin--[acetyl-CoA carboxylase] synthetase activity http://purl.obolibrary.org/obo/GO_0004077 GO:0102300 biolink:MolecularActivity linoleate 9R-lipoxygenase activity Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE. RHEA:31691|MetaCyc:RXN-12760|EC:1.13.11.61 go-plus.json http://purl.obolibrary.org/obo/GO_0102300 GO:0004076 biolink:MolecularActivity biotin synthase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+). RHEA:22060|MetaCyc:2.8.1.6-RXN|EC:2.8.1.6|KEGG_REACTION:R01078 go-plus.json dethiobiotin:sulfur sulfurtransferase activity|biotin synthetase activity http://purl.obolibrary.org/obo/GO_0004076 GO:0004079 biolink:MolecularActivity biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase). MetaCyc:6.3.4.9-RXN|EC:6.3.4.9|RHEA:23668 go-plus.json biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)|biotin-transcarboxylase synthetase activity|biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity|biotin-methylmalonyl-CoA-carboxytransferase synthetase activity|biotin-methylmalonyl-CoA-carboxytransferase ligase activity|biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity|biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)|biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase synthetase|methylmalonyl coenzyme A holotranscarboxylase synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase ligase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity http://purl.obolibrary.org/obo/GO_0004079 GO:0102302 biolink:MolecularActivity mycinamicin VI 2''-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI <=> S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+. RHEA:31643|EC:2.1.1.238|MetaCyc:RXN-12801 go-plus.json http://purl.obolibrary.org/obo/GO_0102302 GO:0004078 biolink:MolecularActivity biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)). MetaCyc:6.3.4.11-RXN|EC:6.3.4.11|RHEA:24376 go-plus.json biotin-methylcrotonoyl-CoA-carboxylase ligase activity|biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity|biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity|beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity|biotin-methylcrotonoyl-CoA-carboxylase synthetase http://purl.obolibrary.org/obo/GO_0004078 GO:0102301 biolink:MolecularActivity gamma-linolenate elongase activity Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide. MetaCyc:RXN-12777 go-plus.json http://purl.obolibrary.org/obo/GO_0102301 GO:0102304 biolink:MolecularActivity sesquithujene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid. RHEA:31991|EC:4.2.3.102|MetaCyc:RXN-12838 go-plus.json http://purl.obolibrary.org/obo/GO_0102304 GO:0004073 biolink:MolecularActivity aspartate-semialdehyde dehydrogenase activity Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH. MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.11|RHEA:24284|KEGG_REACTION:R02291 go-plus.json L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)|aspartate semialdehyde dehydrogenase activity|L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)|L-aspartate-beta-semialdehyde dehydrogenase activity|aspartic beta-semialdehyde dehydrogenase activity|aspartic semialdehyde dehydrogenase activity|ASA dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004073 GO:0004072 biolink:MolecularActivity aspartate kinase activity Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+). MetaCyc:ASPARTATEKIN-RXN|RHEA:23776|EC:2.7.2.4|KEGG_REACTION:R00480 go-plus.json ATP:L-aspartate 4-phosphotransferase activity|aspartic kinase activity|aspartokinase activity|beta-aspartokinase activity http://purl.obolibrary.org/obo/GO_0004072 GO:0102303 biolink:MolecularActivity resveratrol 3,5-O-dimethyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + trans-resveratrol <=> 2 S-adenosyl-L-homocysteine + pterostilbene + 2 H+. RHEA:32103|MetaCyc:RXN-12805|EC:2.1.1.240 go-plus.json http://purl.obolibrary.org/obo/GO_0102303 GO:0004075 biolink:MolecularActivity biotin carboxylase activity Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein. MetaCyc:BIOTIN-CARBOXYL-RXN|RHEA:13501|EC:6.3.4.14 go-plus.json biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity|biotin carboxylase (component of acetyl CoA carboxylase) activity http://purl.obolibrary.org/obo/GO_0004075 GO:0102306 biolink:MolecularActivity benzil reductase [(S)-benzoin-forming] activity Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+. RHEA:25968|MetaCyc:RXN-12898|EC:1.1.1.320 go-plus.json http://purl.obolibrary.org/obo/GO_0102306 GO:0102305 biolink:MolecularActivity (13E)-labda-7,13-dien-15-ol synthase activity Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid. EC:3.1.7.10|RHEA:32075|MetaCyc:RXN-12892 go-plus.json http://purl.obolibrary.org/obo/GO_0102305 GO:0004074 biolink:MolecularActivity biliverdin reductase (NAD(P)+) activity Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+. Reactome:R-HSA-189384|EC:1.3.1.24|MetaCyc:BILIVERDIN-REDUCTASE-RXN go-plus.json bilirubin:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004074 GO:0004080 biolink:MolecularActivity biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)). RHEA:11204|EC:6.3.4.10|MetaCyc:6.3.4.10-RXN go-plus.json holocarboxylase synthetase activity|propionyl-CoA holocarboxylase synthetase activity|biotin-propionyl coenzyme A carboxylase synthetase activity|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity|propionyl coenzyme A holocarboxylase synthetase activity|biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity|biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity http://purl.obolibrary.org/obo/GO_0004080 GO:0102308 biolink:MolecularActivity erythromycin D 3''-o-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin D <=> S-adenosyl-L-homocysteine + erythromycin B + H+. RHEA:32651|MetaCyc:RXN-12924|EC:2.1.1.254 go-plus.json http://purl.obolibrary.org/obo/GO_0102308 GO:0102307 biolink:MolecularActivity erythromycin C 3''-o-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C <=> S-adenosyl-L-homocysteine + erythromycin A + H+. RHEA:32647|MetaCyc:RXN-12923|EC:2.1.1.254 go-plus.json http://purl.obolibrary.org/obo/GO_0102307 GO:0004082 biolink:MolecularActivity bisphosphoglycerate mutase activity Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate. EC:5.4.2.4|RHEA:17765|Reactome:R-HSA-6798335|MetaCyc:BISPHOSPHOGLYCERATE-MUTASE-RXN go-plus.json 2,3-diphosphoglycerate synthase activity|diphosphoglyceromutase activity|2,3-bisphosphoglycerate synthase activity|diphosphoglycerate mutase activity|bisphosphoglyceromutase|3-phospho-D-glycerate 1,2-phosphomutase activity|bisphosphoglycerate synthase activity|2,3-diphosphoglycerate mutase activity|BPGM activity|2,3-bisphosphoglycerate mutase activity|biphosphoglycerate synthase activity|2,3-diphosphoglyceromutase activity|glycerate phosphomutase activity|diphosphoglyceric mutase activity|DPGM http://purl.obolibrary.org/obo/GO_0004082 GO:0102309 biolink:MolecularActivity dTDP-4-oxo-2,6-dideoxy-D-glucose 4-ketoreductase (dTDP-D-oliose producing) activity Catalysis of the reaction: dTDP-D-oliose + NADP <=> dTDP-4-dehydro-2,6-dideoxy-D-glucose + NADPH + H+. MetaCyc:RXN-12930 go-plus.json http://purl.obolibrary.org/obo/GO_0102309 GO:0004081 biolink:MolecularActivity bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate. Reactome:R-HSA-5696197|RHEA:22484|MetaCyc:3.6.1.17-RXN|EC:3.6.1.17 go-plus.json Ap4Aase activity|diguanosinetetraphosphatase (asymmetrical) activity|dinucleoside tetraphosphatase activity|bis(5'-guanosyl)-tetraphosphatase activity|Ap(4)Aase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase|diadenosine P1,P4-tetraphosphatase activity|dinucleosidetetraphosphatase (asymmetrical) activity|Ap(4)A hydrolase activity|diadenosinetetraphosphatase (asymmetrical) activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity|bis(5'-adenosyl)-tetraphosphatase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity|Ap4A hydrolase activity http://purl.obolibrary.org/obo/GO_0004081 GO:0018690 biolink:MolecularActivity 4-methoxybenzoate monooxygenase (O-demethylating) activity Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O. KEGG_REACTION:R01306|MetaCyc:1.14.99.15-RXN|UM-BBD_reactionID:r0154|RHEA:18613|EC:1.14.99.15 go-plus.json piperonylate-4-O-demethylase activity|4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)|4-methoxybenzoate O-demethylase activity|4-methoxybenzoate monooxygenase activity|4-methoxybenzoate 4-monooxygenase (O-demethylating)|p-anisic O-demethylase activity http://purl.obolibrary.org/obo/GO_0018690 GO:0004048 biolink:MolecularActivity anthranilate phosphoribosyltransferase activity Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate. EC:2.4.2.18|RHEA:11768|MetaCyc:PRTRANS-RXN|KEGG_REACTION:R01073 go-plus.json N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity|phosphoribosyl-anthranilate pyrophosphorylase activity|phosphoribosyl-anthranilate diphosphorylase activity|phosphoribosylanthranilate pyrophosphorylase activity|PRT|phosphoribosylanthranilate transferase activity|anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity|anthranilate-PP-ribose-P phosphoribosyltransferase activity|anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0004048 GO:0004047 biolink:MolecularActivity aminomethyltransferase activity Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein. EC:2.1.2.10|Reactome:R-HSA-5693977|RHEA:16945|MetaCyc:GCVT-RXN go-plus.json protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|tetrahydrofolate aminomethyltransferase activity|protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|T-protein|glycine synthase activity|S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|glycine-cleavage system T-protein activity http://purl.obolibrary.org/obo/GO_0004047 GO:0004049 biolink:MolecularActivity anthranilate synthase activity Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. MetaCyc:ANTHRANSYN-RXN|EC:4.1.3.27|RHEA:21732 go-plus.json chorismate pyruvate-lyase (amino-accepting) activity|anthranilate synthetase activity http://purl.obolibrary.org/obo/GO_0004049 GO:0004044 biolink:MolecularActivity amidophosphoribosyltransferase activity Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O. RHEA:14905|EC:2.4.2.14|MetaCyc:PRPPAMIDOTRANS-RXN|Reactome:R-HSA-73815|KEGG_REACTION:R01072 go-plus.json 5-phosphoribosyl-1-pyrophosphate amidotransferase activity|glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity|phosphoribose pyrophosphate amidotransferase activity|glutamine 5-phosphoribosylpyrophosphate amidotransferase activity|glutamine phosphoribosyldiphosphate amidotransferase activity|5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)|glutamine phosphoribosylpyrophosphate amidotransferase activity|phosphoribosyl pyrophosphate amidotransferase activity|alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity|phosphoribosyldiphosphate 5-amidotransferase activity|5'-phosphoribosylpyrophosphate amidotransferase activity|phosphoribosylpyrophosphate glutamyl amidotransferase activity|5-phosphororibosyl-1-pyrophosphate amidotransferase activity http://purl.obolibrary.org/obo/GO_0004044 GO:0004043 biolink:MolecularActivity L-aminoadipate-semialdehyde dehydrogenase activity Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+. RHEA:12308|EC:1.2.1.31|Reactome:R-HSA-70941|MetaCyc:1.2.1.31-RXN go-plus.json aminoadipate semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity|alpha-aminoadipate reductase activity|2-aminoadipic semialdehyde dehydrogenase activity|2-aminoadipate semialdehyde dehydrogenase activity|AAR|aminoadipate-semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity|L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase|L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity|alpha-aminoadipate-semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004043 GO:0004046 biolink:MolecularActivity aminoacylase activity Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid. EC:3.5.1.14|MetaCyc:AMINOACYLASE-RXN|Reactome:R-HSA-9638046|Reactome:R-HSA-5433074|RHEA:15565|Reactome:R-HSA-5579081 go-plus.json amido acid deacylase activity|hippurase activity|short acyl amidoacylase activity|acylase I activity|long acyl amidoacylase activity|benzamidase activity|aminoacylase I activity|L-aminoacylase activity|histozyme activity|dehydropeptidase II activity|N-acyl-L-amino-acid amidohydrolase activity|L-amino-acid acylase activity|alpha-N-acylaminoacid hydrolase activity http://purl.obolibrary.org/obo/GO_0004046 GO:0004045 biolink:MolecularActivity aminoacyl-tRNA hydrolase activity Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. EC:3.1.1.29|RHEA:54448|MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN go-plus.json peptidyl-tRNA hydrolase activity|aminoacyl-transfer ribonucleate hydrolase activity|aminoacyl-tRNA aminoacylhydrolase activity|aminoacyl-tRNA hydrolase reaction|D-tyrosyl-tRNA hydrolase activity|N-substituted aminoacyl transfer RNA hydrolase activity http://purl.obolibrary.org/obo/GO_0004045 GO:0004040 biolink:MolecularActivity amidase activity Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3. MetaCyc:AMIDASE-RXN|EC:3.5.1.4|RHEA:12020|UM-BBD_enzymeID:e0068 go-plus.json acylase activity|acetamidase activity|acylamide amidohydrolase activity|amidohydrolase activity|fatty acylamidase activity|acylamidase activity|N-acetylaminohydrolase activity http://purl.obolibrary.org/obo/GO_0004040 GO:0004042 biolink:MolecularActivity acetyl-CoA:L-glutamate N-acetyltransferase activity Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+). Reactome:R-HSA-70542|KEGG_REACTION:R00259|EC:2.3.1.1|RHEA:24292|MetaCyc:N-ACETYLTRANSFER-RXN go-plus.json amino acid acetyltransferase activity|acetylglutamate acetylglutamate synthetase activity|amino-acid N-acetyltransferase activity|AGAS|N-acetylglutamate synthase activity http://purl.obolibrary.org/obo/GO_0004042 GO:0004041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004041 GO:0018689 biolink:MolecularActivity naphthalene disulfonate 1,2-dioxygenase activity Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene). UM-BBD_enzymeID:e0249 go-plus.json naphthalene disulphonate 1,2-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018689 GO:0018688 biolink:MolecularActivity DDT 2,3-dioxygenase activity Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT. UM-BBD_reactionID:r0450 go-plus.json http://purl.obolibrary.org/obo/GO_0018688 GO:0018685 biolink:MolecularActivity alkane 1-monooxygenase activity Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O. RHEA:19341|EC:1.14.15.3|UM-BBD_enzymeID:e0022|MetaCyc:ALKANE-1-MONOOXYGENASE-RXN go-plus.json alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity|1-hydroxylase activity|fatty acid omega-hydroxylase activity|alkane 1-hydroxylase activity|alkane monooxygenase activity|fatty acid (omega-1)-hydroxylase activity|omega-hydroxylase activity|alkane hydroxylase activity|lauric acid omega-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018685 GO:0018684 biolink:MolecularActivity 2,5-diketocamphane 1,2-monooxygenase Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O. EC:1.14.14.108|UM-BBD_enzymeID:e0302|MetaCyc:CAMPHOR-12-MONOOXYGENASE-RXN|RHEA:34415 go-plus.json (+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)|2,5-diketocamphane lactonizing enzyme activity|camphor ketolactonase I activity|camphor 1,2-monooxygenase activity http://purl.obolibrary.org/obo/GO_0018684 GO:0018687 biolink:MolecularActivity biphenyl 2,3-dioxygenase activity Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+. EC:1.14.12.18|RHEA:18165|UM-BBD_enzymeID:e0089|MetaCyc:1.14.12.18-RXN go-plus.json biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)|biphenyl dioxygenase activity http://purl.obolibrary.org/obo/GO_0018687 GO:0018686 biolink:MolecularActivity 6-hydroxy pseudo-oxynicotine monooxygenase activity Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine. UM-BBD_reactionID:r0480|EC:1.14.18.- go-plus.json http://purl.obolibrary.org/obo/GO_0018686 GO:0018681 biolink:MolecularActivity deisopropylatrazine monooxygenase activity Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine. EC:1.14.15.-|KEGG_REACTION:R05567 go-plus.json http://purl.obolibrary.org/obo/GO_0018681 GO:0018680 biolink:MolecularActivity deethylatrazine monooxygenase activity Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine. EC:1.14.15.-|UM-BBD_reactionID:r0128 go-plus.json http://purl.obolibrary.org/obo/GO_0018680 GO:0018683 biolink:MolecularActivity camphor 5-monooxygenase activity Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O. UM-BBD_enzymeID:e0300|EC:1.14.15.1|RHEA:13525|MetaCyc:R541-RXN go-plus.json D-camphor-exo-hydroxylase activity|bornanone 5-exo-hydroxylase activity|camphor methylene hydroxylase activity|camphor hydroxylase activity|2-bornanone 5-exo-hydroxylase activity|(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)|camphor 5-exohydroxylase activity|camphor 5-exo-methylene hydroxylase activity|methylene monooxygenase activity|d-camphor monooxygenase activity|methylene hydroxylase activity|cytochrome p450-cam activity|camphor 5-exo-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018683 GO:0018682 biolink:MolecularActivity atrazine N-dealkylase activity Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O. EC:1.14.15.-|UM-BBD_reactionID:r0127|MetaCyc:R461-RXN go-plus.json atrazine monooxygenase activity http://purl.obolibrary.org/obo/GO_0018682 GO:0004059 biolink:MolecularActivity aralkylamine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine. Reactome:R-HSA-209792|MetaCyc:ARALKYLAMINE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.87|RHEA:20497 go-plus.json serotonin N-acetyltransferase activity|arylalkylamine N-acetyltransferase activity|serotonin acetylase activity|melatonin rhythm enzyme activity|acetyl-CoA:2-arylethylamine N-acetyltransferase activity|AANAT activity|serotonin acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004059 GO:0004058 biolink:MolecularActivity aromatic-L-amino-acid decarboxylase activity Catalysis of the reaction: L-amino acid + H+ = R-H + CO2. MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN|Reactome:R-HSA-209859|EC:4.1.1.28|Reactome:R-HSA-209924 go-plus.json aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)|hydroxytryptophan decarboxylase activity|aromatic amino acid decarboxylase activity|5-hydroxytryptophan decarboxylase activity|tryptophan decarboxylase activity|aromatic-L-amino-acid carboxy-lyase activity|DOPA decarboxylase activity|L-DOPA decarboxylase activity http://purl.obolibrary.org/obo/GO_0004058 GO:0004055 biolink:MolecularActivity argininosuccinate synthase activity Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate. MetaCyc:ARGSUCCINSYN-RXN|RHEA:10932|EC:6.3.4.5|Reactome:R-HSA-70577 go-plus.json citrulline--aspartate ligase activity|L-citrulline:L-aspartate ligase (AMP-forming)|argininosuccinate synthetase activity|arginosuccinate synthetase activity|arginine succinate synthetase activity|argininosuccinic acid synthetase activity http://purl.obolibrary.org/obo/GO_0004055 GO:0004054 biolink:MolecularActivity arginine kinase activity Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+). MetaCyc:ARGININE-KINASE-RXN|KEGG_REACTION:R00554|RHEA:22940|EC:2.7.3.3 go-plus.json adenosine 5'-triphosphate:L-arginine|adenosine 5'-triphosphate-arginine phosphotransferase activity|arginine phosphokinase activity|ATP:L-arginine N-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004054 GO:0004057 biolink:MolecularActivity arginyltransferase activity Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein. MetaCyc:ARGINYLTRANSFERASE-RXN|RHEA:10208|EC:2.3.2.8 go-plus.json arginine transferase activity|arginyl-tRNA-protein transferase activity|arginyl-transfer ribonucleate-protein transferase activity|arginyl-tRNA--protein transferase activity|arginyl-tRNA protein transferase activity|L-arginyl-tRNA:protein arginyltransferase activity|arginyl-transfer ribonucleate-protein aminoacyltransferase activity http://purl.obolibrary.org/obo/GO_0004057 GO:0004056 biolink:MolecularActivity argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine. RHEA:24020|MetaCyc:ARGSUCCINLYA-RXN|EC:4.3.2.1|Reactome:R-HSA-70573 go-plus.json argininosuccinic acid lyase activity|2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)|arginosuccinase activity|2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)|N-(L-argininosuccinate) arginine-lyase activity|arginine-succinate lyase activity|omega-N-(L-arginino)succinate arginine-lyase activity http://purl.obolibrary.org/obo/GO_0004056 GO:0004051 biolink:MolecularActivity arachidonate 5-lipoxygenase activity Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate. Reactome:R-HSA-9020264|Reactome:R-HSA-9025999|Reactome:R-HSA-9020282|Reactome:R-HSA-9025995|Reactome:R-HSA-9018859|Reactome:R-HSA-9026005|Reactome:R-HSA-9020256|Reactome:R-HSA-9027624|EC:1.13.11.34|Reactome:R-HSA-9018894|Reactome:R-HSA-9027633|Reactome:R-HSA-266051|Reactome:R-HSA-9020278|Reactome:R-HSA-9020277|RHEA:32307|Reactome:R-HSA-265296|MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN|Reactome:R-HSA-9020255|Reactome:R-HSA-9020259|Reactome:R-HSA-9018858|Reactome:R-HSA-9027628|Reactome:R-HSA-9025996|Reactome:R-HSA-9026405|Reactome:R-HSA-9024997|Reactome:R-HSA-9020251|Reactome:R-HSA-9018863 go-plus.json leukotriene A4 synthase|C-5-lipoxygenase activity|arachidonic acid 5-lipoxygenase activity|leukotriene-A4 synthase activity|delta(5)-lipoxygenase activity|5Delta-lipoxygenase activity|5-delta-lipoxygenase activity|arachidonic 5-lipoxygenase activity|delta5-lipoxygenase activity|LTA synthase activity|arachidonate:oxygen 5-oxidoreductase activity|leukotriene-A(4) synthase activity|5-lipoxygenase activity http://purl.obolibrary.org/obo/GO_0004051 GO:0004050 biolink:MolecularActivity obsolete apyrase activity OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate. go-plus.json apyrase activity http://purl.obolibrary.org/obo/GO_0004050 GO:0004053 biolink:MolecularActivity arginase activity Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea. MetaCyc:ARGINASE-RXN|Reactome:R-HSA-452036|Reactome:R-HSA-70569|RHEA:20569|EC:3.5.3.1 go-plus.json L-arginase activity|arginine transamidinase activity|canavanase activity|arginine amidinase activity|L-arginine amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0004053 GO:0004052 biolink:MolecularActivity arachidonate 12(S)-lipoxygenase activity Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate. Reactome:R-HSA-9026007|Reactome:R-HSA-9024983|Reactome:R-HSA-9025957|EC:1.13.11.31|Reactome:R-HSA-9026006|Reactome:R-HSA-2161950|RHEA:10428|MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN|KEGG_REACTION:R01596|Reactome:R-HSA-2161964|Reactome:R-HSA-2161948 go-plus.json leukotriene A4 synthase|12-lipoxygenase activity|delta12-lipoxygenase activity|C-12 lipoxygenase activity|arachidonate:oxygen 12-oxidoreductase activity|12Delta-lipoxygenase activity|12S-lipoxygenase activity|LTA4 synthase activity http://purl.obolibrary.org/obo/GO_0004052 GO:0004060 biolink:MolecularActivity arylamine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine. MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN|RHEA:16613|EC:2.3.1.5|Reactome:R-HSA-174967|Reactome:R-HSA-174963|UM-BBD_enzymeID:e0341 go-plus.json 4-aminobiphenyl N-acetyltransferase activity|acetyl-CoA:arylamine N-acetyltransferase activity|beta-naphthylamine N-acetyltransferase activity|2-naphthylamine N-acetyltransferase activity|p-aminosalicylate N-acetyltransferase activity|indoleamine N-acetyltransferase activity|arylamine acetyltransferase activity|arylamine acetylase activity|acetyl CoA-arylamine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004060 GO:0018699 biolink:MolecularActivity 1,1,1-trichloroethane reductive dehalogenase activity Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl. UM-BBD_reactionID:r1007|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018699 GO:0018696 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018696 GO:0018695 biolink:MolecularActivity 4-cresol dehydrogenase (hydroxylating) activity Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor. EC:1.17.9.1|UM-BBD_reactionID:r0272|RHEA:15141|MetaCyc:1.17.99.1-RXN go-plus.json p-cresol-(acceptor) oxidoreductase (hydroxylating) activity|4-cresol dehydrogenase activity|p-cresol methylhydroxylase activity|4-cresol:acceptor oxidoreductase (methyl-hydroxylating) http://purl.obolibrary.org/obo/GO_0018695 GO:0018698 biolink:MolecularActivity vinyl chloride reductive dehalogenase activity Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene. MetaCyc:VCREDCHLOR-RXN|UM-BBD_reactionID:r0352|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018698 GO:0018697 biolink:MolecularActivity carbonyl sulfide nitrogenase activity Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide. UM-BBD_reactionID:r0600|EC:1.18.6.1 go-plus.json carbonyl sulphide nitrogenase activity http://purl.obolibrary.org/obo/GO_0018697 GO:0018692 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018692 GO:0018691 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018691 GO:0018694 biolink:MolecularActivity p-cymene methyl hydroxylase activity Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol. UM-BBD_reactionID:r0392|EC:1.14.15.25|MetaCyc:RXN-661|RHEA:51604 go-plus.json http://purl.obolibrary.org/obo/GO_0018694 GO:0018693 biolink:MolecularActivity ethylbenzene hydroxylase activity Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2). EC:1.17.99.2|UM-BBD_reactionID:r0234|KEGG_REACTION:R05745|RHEA:17897|MetaCyc:RXN-1301 go-plus.json ethylbenzene dehydrogenase activity|ethylbenzene:(acceptor) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018693 GO:0004029 biolink:MolecularActivity aldehyde dehydrogenase (NAD+) activity Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+. Reactome:R-HSA-5696091|UM-BBD_enzymeID:e0024|Reactome:R-HSA-6813749|MetaCyc:ALDHDEHYDROG-RXN|Wikipedia:Aldehyde_dehydrogenase_(NAD+)|Reactome:R-HSA-389609|Reactome:R-HSA-71691|Reactome:R-HSA-71723|Reactome:R-HSA-6808487|Reactome:R-HSA-6808496|Reactome:R-HSA-5692261|EC:1.2.1.3|RHEA:16185|Reactome:R-HSA-380608 go-plus.json aldehyde:NAD+ oxidoreductase activity|m-methylbenzaldehyde dehydrogenase activity|NAD-aldehyde dehydrogenase activity|NAD-dependent aldehyde dehydrogenase activity|CoA-independent aldehyde dehydrogenase activity|propionaldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD+)|NAD-dependent 4-hydroxynonenal dehydrogenase activity|NAD-linked aldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004029 GO:0004026 biolink:MolecularActivity alcohol O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester. MetaCyc:ALCOHOL-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.84|RHEA:17229 go-plus.json alcohol acetyltransferase activity|AATASE activity|acetyl-CoA:alcohol O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004026 GO:0004025 biolink:MolecularActivity alcohol dehydrogenase activity, iron-dependent Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron. go-plus.json http://purl.obolibrary.org/obo/GO_0004025 GO:0004028 biolink:MolecularActivity 3-chloroallyl aldehyde dehydrogenase activity Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid. UM-BBD_enzymeID:e0432|Reactome:R-HSA-71260 go-plus.json http://purl.obolibrary.org/obo/GO_0004028 GO:0004027 biolink:MolecularActivity alcohol sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate. Reactome:R-HSA-176609|RHEA:22552|EC:2.8.2.2|Reactome:R-HSA-176494|MetaCyc:ALCOHOL-SULFOTRANSFERASE-RXN go-plus.json delta5-3beta-hydroxysteroid sulfokinase activity|5alpha-androstenol sulfotransferase activity|3beta-hydroxysteroid sulfotransferase activity|sterol sulfokinase activity|dehydroepiandrosterone sulfotransferase activity|estrogen sulfokinase activity|3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity|HST|alcohol/hydroxysteroid sulfotransferase activity|steroid alcohol sulfotransferase|sterol sulfotransferase activity|hydroxysteroid sulfotransferase activity|estrogen sulfotransferase|alcohol sulphotransferase activity|3-hydroxysteroid sulfotransferase activity|3beta-hydroxy steroid sulfotransferase activity|steroid sulfokinase activity http://purl.obolibrary.org/obo/GO_0004027 goslim_chembl GO:0004022 biolink:MolecularActivity alcohol dehydrogenase (NAD+) activity Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+. UM-BBD_enzymeID:e0023|MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN|RHEA:10740|Reactome:R-HSA-2162078|EC:1.1.1.1 go-plus.json alcohol:NAD+ oxidoreductase|aliphatic alcohol dehydrogenase|NADH-alcohol dehydrogenase|NADH-aldehyde dehydrogenase|ADH|NAD-dependent alcohol dehydrogenase|yeast alcohol dehydrogenase|ethanol dehydrogenase|primary alcohol dehydrogenase|aldo-keto reductase (NAD) activity|aldehyde dehydrogenase (NAD) activity|alcohol dehydrogenase activity|NAD-specific aromatic alcohol dehydrogenase http://purl.obolibrary.org/obo/GO_0004022 GO:0004021 biolink:MolecularActivity L-alanine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. KEGG_REACTION:R00258|EC:2.6.1.2|RHEA:19453|Reactome:R-HSA-507749|MetaCyc:ALANINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-70524|Reactome:R-HSA-507775|Reactome:R-HSA-70523 go-plus.json glutamic--alanine transaminase activity|pyruvate-glutamate transaminase activity|alanine-pyruvate aminotransferase activity|glutamic--pyruvic transaminase activity|GPT|ALT|glutamic acid-pyruvic acid transaminase activity|pyruvate-alanine aminotransferase activity|glutamic-pyruvic aminotransferase activity|L-alanine aminotransferase activity|alanine aminotransferase activity|alanine-alpha-ketoglutarate aminotransferase activity|beta-alanine aminotransferase|L-alanine-alpha-ketoglutarate aminotransferase activity|pyruvate transaminase activity|alanine transaminase activity|L-alanine transaminase activity http://purl.obolibrary.org/obo/GO_0004021 GO:0004024 biolink:MolecularActivity alcohol dehydrogenase activity, zinc-dependent Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc. Reactome:R-HSA-71707 go-plus.json http://purl.obolibrary.org/obo/GO_0004024 GO:0004023 biolink:MolecularActivity alcohol dehydrogenase activity, metal ion-independent Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion. go-plus.json http://purl.obolibrary.org/obo/GO_0004023 GO:0004020 biolink:MolecularActivity adenylylsulfate kinase activity Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate. Reactome:R-HSA-3560785|Reactome:R-HSA-174389|EC:2.7.1.25|MetaCyc:ADENYLYLSULFKIN-RXN|RHEA:24152 go-plus.json adenylyl-sulphate kinase activity|adenosine phosphosulfate kinase activity|adenosine-5'-phosphosulfate-3'-phosphokinase activity|5'-phosphoadenosine sulfate kinase activity|adenosine 5'-phosphosulfate kinase activity|adenosine-5'-phosphosulfate 3'-phosphotransferase activity|ATP:adenylyl-sulfate 3'-phosphotransferase activity|APS kinase activity|adenylylsulfate kinase (phosphorylating)|adenylyl-sulfate kinase activity|adenosine phosphosulfokinase activity|adenosine-5'-phosphosulphate 3'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004020 GO:0018667 biolink:MolecularActivity cyclohexanone monooxygenase activity Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O. RHEA:24068|EC:1.14.13.22|MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0166 go-plus.json cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)|cyclohexanone 1,2-monooxygenase activity|cyclohexanone oxygenase activity|cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity http://purl.obolibrary.org/obo/GO_0018667 GO:0018666 biolink:MolecularActivity 2,4-dichlorophenol 6-monooxygenase activity Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O. MetaCyc:24-DICHLOROPHENOL-6-MONOOXYGENASE-RXN|EC:1.14.13.20|UM-BBD_enzymeID:e0152|RHEA:20920 go-plus.json 2,4-dichlorophenol hydroxylase activity|2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)|2,4-dichlorophenol monooxygenase activity http://purl.obolibrary.org/obo/GO_0018666 GO:0018669 biolink:MolecularActivity 3-hydroxybenzoate 6-monooxygenase activity Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+). RHEA:22692|MetaCyc:3-HYDROXYBENZOATE-6-MONOOXYGENASE-RXN|EC:1.14.13.24|UM-BBD_reactionID:r0402|KEGG_REACTION:R02589 go-plus.json 3-hydroxybenzoate 6-hydroxylase activity|m-hydroxybenzoate 6-hydroxylase activity|3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)|3-hydroxybenzoic acid-6-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018669 GO:0018668 biolink:MolecularActivity 3-hydroxybenzoate 4-monooxygenase activity Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+). UM-BBD_reactionID:r0153|RHEA:11480|MetaCyc:3-HYDROXYBENZOATE-4-MONOOXYGENASE-RXN|EC:1.14.13.23|KEGG_REACTION:R01628 go-plus.json 3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|3-hydroxybenzoate 4-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018668 GO:0018663 biolink:MolecularActivity 2,6-dihydroxypyridine 3-monooxygenase activity Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+). MetaCyc:1.14.13.10-RXN|KEGG_REACTION:R04130|EC:1.14.13.10|RHEA:16917|UM-BBD_reactionID:r0479 go-plus.json 2,6-dihydroxypyridine oxidase activity|2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating) http://purl.obolibrary.org/obo/GO_0018663 GO:0018662 biolink:MolecularActivity phenol 2-monooxygenase activity Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O. UM-BBD_enzymeID:e0208|RHEA:17061|EC:1.14.13.7|MetaCyc:PHENOL-2-MONOOXYGENASE-RXN go-plus.json phenol hydroxylase activity|phenol o-hydroxylase activity|phenol,NADPH:oxygen oxidoreductase (2-hydroxylating) http://purl.obolibrary.org/obo/GO_0018662 GO:0018665 biolink:MolecularActivity 4-hydroxyphenylacetate 1-monooxygenase activity Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O. EC:1.14.13.18|MetaCyc:1.14.13.18-RXN|UM-BBD_reactionID:r0300 go-plus.json 4-hydroxyphenylacetate 1-hydroxylase activity|4-hydroxyphenylacetic 1-hydroxylase activity|4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)|4-HPA 1-hydroxylase activity|4-hydroxyphenyl-acetate 1-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018665 GO:0018664 biolink:MolecularActivity benzoate 4-monooxygenase activity Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+). MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN|KEGG_REACTION:R01295|RHEA:18033|UM-BBD_reactionID:r0623|EC:1.14.14.92 go-plus.json p-hydroxybenzoate hydroxylase activity|benzoate-p-hydroxylase activity|benzoic acid 4-hydroxylase activity|benzoate-para-hydroxylase activity|benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|benzoate 4-hydroxylase activity|4-hydroxybenzoic hydroxylase activity|benzoic 4-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018664 GO:0018661 biolink:MolecularActivity orcinol 2-monooxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+). RHEA:19601|UM-BBD_reactionID:r0092|EC:1.14.13.6|MetaCyc:ORCINOL-2-MONOOXYGENASE-RXN|KEGG_REACTION:R02830 go-plus.json orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)|orcinol hydroxylase activity http://purl.obolibrary.org/obo/GO_0018661 GO:0018660 biolink:MolecularActivity 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O. RHEA:16681|EC:1.14.14.9|KEGG_REACTION:R02698 go-plus.json 4 HPA 3-hydroxylase activity|p-hydroxyphenylacetate hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetate 3-monooxygenase activity|4-hydroxyphenylacetate 3-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018660 GO:0004037 biolink:MolecularActivity allantoicase activity Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea. EC:3.5.3.4|MetaCyc:ALLANTOICASE-RXN|RHEA:11016|KEGG_REACTION:R02422 go-plus.json allantoate amidinohydrolase activity|allantoine amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0004037 GO:0004036 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004036 GO:0004039 biolink:MolecularActivity allophanate hydrolase activity Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+). EC:3.5.1.54|RHEA:19029|UM-BBD_reactionID:r0848|MetaCyc:ALLOPHANATE-HYDROLASE-RXN|KEGG_REACTION:R00005 go-plus.json allophanate lyase activity|urea-1-carboxylate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0004039 GO:0004038 biolink:MolecularActivity allantoinase activity Catalysis of the reaction: allantoin + H2O = allantoate. RHEA:17029|EC:3.5.2.5|MetaCyc:ALLANTOINASE-RXN go-plus.json (S)-allantoin amidohydrolase activity http://purl.obolibrary.org/obo/GO_0004038 GO:0004033 biolink:MolecularActivity aldo-keto reductase (NADP) activity Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+. Reactome:R-HSA-193824|Reactome:R-HSA-193755|Reactome:R-HSA-193821|Reactome:R-HSA-5423637|Reactome:R-HSA-9027531|Reactome:R-HSA-193800|Reactome:R-HSA-9027562|Reactome:R-HSA-192033|Reactome:R-HSA-198845|Reactome:R-HSA-192067|Reactome:R-HSA-192160|Reactome:R-HSA-9027598|Reactome:R-HSA-193746|Reactome:R-HSA-193781|Reactome:R-HSA-192036|Reactome:R-HSA-2855252|Reactome:R-HSA-193841|Reactome:R-HSA-9027600|Reactome:R-HSA-193758|Reactome:R-HSA-5692232 go-plus.json aldo-keto reductase activity|aldo-keto reductase (NADP+) activity|NADPH-dependent aldo-keto reductase activity|alcohol dehydrogenase (NADP+) activity http://purl.obolibrary.org/obo/GO_0004033 GO:0004032 biolink:MolecularActivity alditol:NADP+ 1-oxidoreductase activity Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+. MetaCyc:ALDEHYDE-REDUCTASE-RXN|EC:1.1.1.21|Reactome:R-HSA-5652172|Reactome:R-HSA-196060|RHEA:12789|KEGG_REACTION:R02820 go-plus.json polyol dehydrogenase (NADP(+)) activity|aldose reductase activity|aldehyde reductase activity http://purl.obolibrary.org/obo/GO_0004032 GO:0004035 biolink:MolecularActivity alkaline phosphatase activity Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. Reactome:R-HSA-8878787|EC:3.1.3.1|MetaCyc:ALKAPHOSPHA-RXN go-plus.json alkaline phosphomonoesterase activity|glycerophosphatase activity|orthophosphoric-monoester phosphohydrolase (alkaline optimum)|phosphomonoesterase activity|alkaline phosphohydrolase activity|alkaline phenyl phosphatase activity|phosphate-monoester phosphohydrolase (alkaline optimum) http://purl.obolibrary.org/obo/GO_0004035 GO:0004034 biolink:MolecularActivity aldose 1-epimerase activity Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose. RHEA:10264|EC:5.1.3.3|MetaCyc:ALDOSE-1-EPIMERASE-RXN go-plus.json mutarotase activity|aldose mutarotase activity http://purl.obolibrary.org/obo/GO_0004034 GO:0004031 biolink:MolecularActivity aldehyde oxidase activity Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide. EC:1.2.3.1|RHEA:16829|MetaCyc:ALDEHYDE-OXIDASE-RXN|Reactome:R-HSA-3204311 go-plus.json aldehyde:oxygen oxidoreductase activity|quinoline oxidase activity http://purl.obolibrary.org/obo/GO_0004031 GO:0004030 biolink:MolecularActivity aldehyde dehydrogenase [NAD(P)+] activity Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+. Reactome:R-HSA-6808464|EC:1.2.1.5|Reactome:R-HSA-5692283|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN|Reactome:R-HSA-5696080 go-plus.json aldehyde:NAD(P)+ oxidoreductase activity|ALDH http://purl.obolibrary.org/obo/GO_0004030 GO:0018678 biolink:MolecularActivity 4-hydroxybenzoate 1-hydroxylase activity Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2. EC:1.14.13.64|UM-BBD_reactionID:r0752|MetaCyc:1.14.13.64-RXN go-plus.json 4-hydroxybenzoate 1-monooxygenase activity|4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating) http://purl.obolibrary.org/obo/GO_0018678 GO:0018677 biolink:MolecularActivity pentachlorophenol monooxygenase activity Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride. EC:1.14.13.50|MetaCyc:PCP4MONO-RXN|RHEA:18685|UM-BBD_enzymeID:e0148 go-plus.json PCP hydroxylase activity|pentachlorophenol dehalogenase activity|pentachlorophenol 4-monooxygenase activity|pentachlorophenol hydroxylase activity|pentachlorophenol dechlorinase activity|PCB 4-monooxygenase activity|PCB4MO activity|pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)|PcpB http://purl.obolibrary.org/obo/GO_0018677 GO:0018679 biolink:MolecularActivity dibenzothiophene-5,5-dioxide monooxygenase activity Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate. EC:1.14.14.-|UM-BBD_reactionID:r0235|MetaCyc:RXN-623 go-plus.json http://purl.obolibrary.org/obo/GO_0018679 GO:0018674 biolink:MolecularActivity (S)-limonene 3-monooxygenase activity Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+). UM-BBD_reactionID:r0739|EC:1.14.14.99|KEGG_REACTION:R02469|RHEA:15129|MetaCyc:--LIMONENE-3-MONOOXYGENASE-RXN go-plus.json (-)-limonene 3-hydroxylase activity|limonene 3-hydroxylase activity|(-)-limonene 3-monooxygenase activity|(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity|(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) http://purl.obolibrary.org/obo/GO_0018674 GO:0018673 biolink:MolecularActivity anthraniloyl-CoA monooxygenase activity Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+. EC:1.14.13.40|UM-BBD_reactionID:r0568|MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN go-plus.json 2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)|2-aminobenzoyl-CoA monooxygenase/reductase activity|anthraniloyl coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_0018673 GO:0018676 biolink:MolecularActivity (S)-limonene 7-monooxygenase activity Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+). UM-BBD_reactionID:r0728|EC:1.14.14.52|RHEA:23432|MetaCyc:--LIMONENE-7-MONOOXYGENASE-RXN|KEGG_REACTION:R02470 go-plus.json (-)-limonene 7-monooxygenase activity http://purl.obolibrary.org/obo/GO_0018676 GO:0018675 biolink:MolecularActivity (S)-limonene 6-monooxygenase activity Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O. UM-BBD_reactionID:r0713|EC:1.14.14.51|RHEA:17945|MetaCyc:--LIMONENE-6-MONOOXYGENASE-RXN go-plus.json (-)-limonene 6-hydroxylase activity|(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity|limonene 6-hydroxylase activity|(-)-limonene 6-monooxygenase activity|(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) http://purl.obolibrary.org/obo/GO_0018675 GO:0018670 biolink:MolecularActivity 4-aminobenzoate 1-monooxygenase activity Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2. UM-BBD_reactionID:r0597|MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN|EC:1.14.13.27 go-plus.json 4-aminobenzoate monooxygenase activity|4-aminobenzoate dehydrogenase activity|4-aminobenzoate hydroxylase activity|4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating) http://purl.obolibrary.org/obo/GO_0018670 GO:0018672 biolink:MolecularActivity anthranilate 3-monooxygenase (deaminating) activity Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+). UM-BBD_reactionID:r0578|RHEA:21236|MetaCyc:1.14.13.35-RXN|KEGG_REACTION:R00980|EC:1.14.13.35 go-plus.json anthranilate 2,3-hydroxylase (deaminating) activity|anthranilate hydroxylase (deaminating) activity|anthranilate 2,3-dioxygenase (deaminating)|anthranilate hydroxylase activity|anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating) http://purl.obolibrary.org/obo/GO_0018672 GO:0018671 biolink:MolecularActivity 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O. MetaCyc:1.14.13.33-RXN|EC:1.14.13.33 go-plus.json 4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)|4-hydroxybenzoate 3-hydroxylase activity|4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))|4-hydroxybenzoate-3-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018671 PR:000019996 biolink:Protein somatoliberin proteolytic cleavage product A somatoliberin that has been processed by proteolytic cleavage. go-plus.json GHRH/ClvPrd http://purl.obolibrary.org/obo/PR_000019996 PR:000019995 biolink:Protein growth hormone receptor proteolytic cleavage product A growth hormone receptor that has been processed by proteolytic cleavage. go-plus.json GHR/ClvPrd http://purl.obolibrary.org/obo/PR_000019995 GO:0102351 biolink:MolecularActivity gamma-aminobutyrate transaminase (glyoxylate dependent) activity Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine. RHEA:32267|EC:2.6.1.96|MetaCyc:RXN-13328 go-plus.json http://purl.obolibrary.org/obo/GO_0102351 GO:0102350 biolink:MolecularActivity trans-cerot-2-enoyl-CoA reductase activity Catalysis of the reaction: hexacosanoyl-CoA(4-) + NADP(3-) <=> trans-2-hexacosenoyl-CoA + NADPH + H+. MetaCyc:RXN-13309 go-plus.json http://purl.obolibrary.org/obo/GO_0102350 GO:0102353 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102353 PR:000019999 biolink:Protein appetite-regulating hormone proteolytic cleavage product An appetite-regulating hormone that has been processed by proteolytic cleavage. go-plus.json GHRL/ClvPrd http://purl.obolibrary.org/obo/PR_000019999 GO:0102352 biolink:MolecularActivity phosphatidate kinase activity Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate. MetaCyc:RXN-13336 go-plus.json http://purl.obolibrary.org/obo/GO_0102352 GO:0102355 biolink:MolecularActivity 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+. MetaCyc:RXN-13371|RHEA:33967|EC:3.1.1.91 go-plus.json http://purl.obolibrary.org/obo/GO_0102355 GO:0102354 biolink:MolecularActivity 11-cis-retinol dehydrogenase activity Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+. MetaCyc:RXN-13363|RHEA:54912 go-plus.json http://purl.obolibrary.org/obo/GO_0102354 GO:0102357 biolink:MolecularActivity mithramycin dehydrogenase activity Catalysis of the reaction: mithramycin + NADP <=> mithramycin DK + NADPH + H+. MetaCyc:RXN-13385 go-plus.json http://purl.obolibrary.org/obo/GO_0102357 GO:0043610 biolink:BiologicalProcess regulation of carbohydrate utilization Any process that modulates the frequency, rate or extent of carbohydrate utilization. go-plus.json regulation of sugar utilization http://purl.obolibrary.org/obo/GO_0043610 GO:0102356 biolink:MolecularActivity isoitalicene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene. MetaCyc:RXN-13373 go-plus.json http://purl.obolibrary.org/obo/GO_0102356 GO:0102359 biolink:MolecularActivity daphnetin 4-O-beta-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+. MetaCyc:RXN-13450|EC:2.4.1.126 go-plus.json http://purl.obolibrary.org/obo/GO_0102359 GO:0102358 biolink:MolecularActivity daphnetin-8-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxycoumarin + H+. MetaCyc:RXN-13448 go-plus.json http://purl.obolibrary.org/obo/GO_0102358 GO:0043616 biolink:BiologicalProcess keratinocyte proliferation The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. go-plus.json http://purl.obolibrary.org/obo/GO_0043616 GO:0043615 biolink:BiologicalProcess astrocyte cell migration The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. go-plus.json astrocytic glial cell migration|astrocyte migration http://purl.obolibrary.org/obo/GO_0043615 GO:0043618 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to stress Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0043618 GO:0043617 biolink:BiologicalProcess cellular response to sucrose starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose. go-plus.json http://purl.obolibrary.org/obo/GO_0043617 GO:0043612 biolink:BiologicalProcess isoprene biosynthetic process The chemical reactions and pathways resulting in the formation of isoprene, C5H8. go-plus.json 2-methyl-1,3-butadiene biosynthetic process|2-methyl-1,3-butadiene biosynthesis|hemiterpene biosynthetic process|hemiterpene biosynthesis http://purl.obolibrary.org/obo/GO_0043612 CHEBI:78022 biolink:ChemicalSubstance 1-stearoyl-2-(alpha-linolenoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78022 chebi_ph7_3 GO:0043611 biolink:BiologicalProcess isoprene metabolic process The chemical reactions and pathways involving isoprene, C5H8. go-plus.json 2-methyl-1,3-butadiene metabolism|hemiterpene metabolic process|hemiterpene metabolism|isoprene metabolism|2-methyl-1,3-butadiene metabolic process http://purl.obolibrary.org/obo/GO_0043611 GO:0043614 biolink:CellularComponent multi-eIF complex A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5. go-plus.json multifactor translation initiation factor (eIF) complex http://purl.obolibrary.org/obo/GO_0043614 GO:0043613 biolink:BiologicalProcess isoprene catabolic process The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8. go-plus.json 2-methyl-1,3-butadiene catabolism|hemiterpene catabolism|hemiterpene catabolic process|2-methyl-1,3-butadiene catabolic process http://purl.obolibrary.org/obo/GO_0043613 GO:0043619 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to oxidative stress Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0043619 CL:0019019 biolink:Cell tracheobronchial smooth muscle cell A smooth muscle cell that is part of the tracheobronchial tree. go-plus.json smooth muscle cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0019019 GO:0102360 biolink:MolecularActivity daphnetin 3-O-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+. EC:2.4.1.91|MetaCyc:RXN-13452 go-plus.json http://purl.obolibrary.org/obo/GO_0102360 CL:0019018 biolink:Cell blood vessel smooth muscle cell A smooth muscle cell that is part of any blood vessel. go-plus.json smooth muscle cell of blood vessel http://purl.obolibrary.org/obo/CL_0019018 CL:0019017 biolink:Cell lymphatic vessel smooth muscle cell A smooth muscle cell that is part of any lymphatic vessel. go-plus.json smooth muscle cell of lymphatic vessel http://purl.obolibrary.org/obo/CL_0019017 GO:0102362 biolink:MolecularActivity esculetin 3-O-glucosyltransferase activity Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+. MetaCyc:RXN-13472 go-plus.json http://purl.obolibrary.org/obo/GO_0102362 GO:0102361 biolink:MolecularActivity esculetin 4-O-beta-glucosyltransferase activity Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+. EC:2.4.1.126|MetaCyc:RXN-13471 go-plus.json http://purl.obolibrary.org/obo/GO_0102361 GO:0102363 biolink:MolecularActivity isoscopoletin-O-methyltransferase activity Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine <=> scoparone + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-13475 go-plus.json http://purl.obolibrary.org/obo/GO_0102363 GO:0102366 biolink:MolecularActivity 7-beta-hydroxytaxusin 2-alpha-hydroxylase activity Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O. MetaCyc:RXN-13487 go-plus.json http://purl.obolibrary.org/obo/GO_0102366 GO:0102365 biolink:MolecularActivity taxusin 2-alpha-hydroxylase activity Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O. MetaCyc:RXN-13486 go-plus.json http://purl.obolibrary.org/obo/GO_0102365 GO:0043621 biolink:MolecularActivity protein self-association Binding to a domain within the same polypeptide. go-plus.json protein self binding|protein self association|intramolecular protein binding http://purl.obolibrary.org/obo/GO_0043621 goslim_chembl GO:0102368 biolink:MolecularActivity beta-amyrin 30-monooxygenase activity Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O. MetaCyc:RXN-13489 go-plus.json http://purl.obolibrary.org/obo/GO_0102368 GO:0102367 biolink:MolecularActivity 2-alpha-hydroxytaxusin 7-beta-hydroxylase activity Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O. MetaCyc:RXN-13488 go-plus.json http://purl.obolibrary.org/obo/GO_0102367 GO:0043620 biolink:BiologicalProcess regulation of DNA-templated transcription in response to stress Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json regulation of DNA-dependent transcription in response to stress http://purl.obolibrary.org/obo/GO_0043620 GO:0102369 biolink:MolecularActivity 11alpha-30-dihydroxy beta-amyrin dehydrogenase activity Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O. MetaCyc:RXN-13491 go-plus.json http://purl.obolibrary.org/obo/GO_0102369 OBO:GOCHE_35523 biolink:OntologyClass substance with bronchodilator agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35523 3_STAR GO:0043627 biolink:BiologicalProcess response to estrogen Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. go-plus.json response to estrogen stimulus|response to oestrogen stimulus http://purl.obolibrary.org/obo/GO_0043627 GO:0043626 biolink:CellularComponent PCNA complex A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation. go-plus.json PCNA homotrimer|proliferating cell nuclear antigen complex|sliding clamp http://purl.obolibrary.org/obo/GO_0043626 GO:0043629 biolink:BiologicalProcess ncRNA polyadenylation The enzymatic addition of a sequence of adenylyl residues at the 3' end of a non-coding RNA (ncRNA) molecule. In eukaryotes, substrates include nuclear non-coding RNAs such as precursors and a variety of incorrectly processed forms of snRNAs, snoRNAs, rRNAs, and tRNAs, as well as discarded RNA fragments which have been removed from ncRNA primary transcripts. Polyadenylation of precursors is often linked to termination of transcription, but polyadenylation of RNAs targeted for degradation may also occur post-transcriptionally. This polyadenylation is important both for 3'-end processing to produce mature ncRNA species and also for targeting incorrectly processed or discarded RNA molecules for degradation. go-plus.json non-coding RNA polyadenylation http://purl.obolibrary.org/obo/GO_0043629 GO:0043628 biolink:BiologicalProcess ncRNA 3'-end processing Any process involved in forming the mature 3' end of a non-coding RNA molecule. go-plus.json ncRNA 3' end processing http://purl.obolibrary.org/obo/GO_0043628 GO:0043623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043623 CHEBI:78033 biolink:ChemicalSubstance methyl arachidonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78033 chebi_ph7_3 GO:0043622 biolink:BiologicalProcess cortical microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell. go-plus.json cortical microtubule organisation|cortical microtubule organization and biogenesis|cortical microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0043622 GO:0043625 biolink:CellularComponent delta DNA polymerase complex A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair. go-plus.json delta-DNA polymerase complex http://purl.obolibrary.org/obo/GO_0043625 GO:0043624 biolink:BiologicalProcess cellular protein complex disassembly The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups. go-plus.json http://purl.obolibrary.org/obo/GO_0043624 CHEBI:78035 biolink:ChemicalSubstance 12(S)-HPETE methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_78035 chebi_ph7_3 CHEBI:78034 biolink:ChemicalSubstance 12(R)-HPETE methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_78034 chebi_ph7_3 GO:0102371 biolink:MolecularActivity betulin dehydrogenase activity Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O. MetaCyc:RXN-13498 go-plus.json http://purl.obolibrary.org/obo/GO_0102371 PR:000020966 biolink:Protein polymeric immunoglobulin receptor proteolytic cleavage product A polymeric immunoglobulin receptor that has been processed by proteolytic cleavage. go-plus.json PIGR/ClvPrd http://purl.obolibrary.org/obo/PR_000020966 PR:000019973 biolink:Protein gastrin proteolytic cleavage product A gastrin that has been processed by proteolytic cleavage. go-plus.json GAST/ClvPrd http://purl.obolibrary.org/obo/PR_000019973 GO:0102370 biolink:MolecularActivity lupeol 28-monooxygenase activity Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O. MetaCyc:RXN-13497 go-plus.json http://purl.obolibrary.org/obo/GO_0102370 GO:0102373 biolink:MolecularActivity uvaol dehydrogenase activity Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O. MetaCyc:RXN-13501|EC:1.14.14.126 go-plus.json http://purl.obolibrary.org/obo/GO_0102373 GO:0102372 biolink:MolecularActivity alpha-amyrin 28-monooxygenase activity Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O. MetaCyc:RXN-13500 go-plus.json http://purl.obolibrary.org/obo/GO_0102372 GO:0102375 biolink:MolecularActivity 11-oxo-beta-amyrin 30-oxidase activity Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O. RHEA:35499|MetaCyc:RXN-13506|EC:1.14.14.115 go-plus.json http://purl.obolibrary.org/obo/GO_0102375 GO:0102374 biolink:MolecularActivity ursolic aldehyde 28-monooxygenase activity Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O. MetaCyc:RXN-13502|EC:1.14.14.126 go-plus.json http://purl.obolibrary.org/obo/GO_0102374 GO:0043630 biolink:BiologicalProcess ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a non-coding RNA, occurring as part of the process of polyadenylation-dependent non-coding RNA catabolism. go-plus.json ncRNA polyadenylation during polyadenylation-dependent ncRNA catabolic process|ncRNA polyadenylation involved in poly(A)-dependent ncRNA catabolic process http://purl.obolibrary.org/obo/GO_0043630 GO:0102377 biolink:MolecularActivity steviol 13-O glucosyltransferase activity Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+. MetaCyc:RXN-13511 go-plus.json http://purl.obolibrary.org/obo/GO_0102377 GO:0102376 biolink:MolecularActivity lupeol 28-oxidase activity Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O. MetaCyc:RXN-13507 go-plus.json http://purl.obolibrary.org/obo/GO_0102376 GO:0043632 biolink:BiologicalProcess modification-dependent macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043632 GO:0102379 biolink:MolecularActivity steviolbioside glucosyltransferase activity (stevioside forming) Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+. MetaCyc:RXN-13514 go-plus.json http://purl.obolibrary.org/obo/GO_0102379 GO:0102378 biolink:MolecularActivity steviolmonoside glucosyltransferase activity Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+. MetaCyc:RXN-13512 go-plus.json http://purl.obolibrary.org/obo/GO_0102378 GO:0043631 biolink:BiologicalProcess RNA polyadenylation The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043631 CL:0019003 biolink:Cell tracheobronchial goblet cell Any goblet cell that is part of the tracheobronchial epithelium. go-plus.json goblet cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0019003 CL:0019002 biolink:Cell tracheobronchial chondrocyte Any chondrocyte that is part of the tracheobronchial tree. go-plus.json chondrocyte of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0019002 GO:0043638 biolink:BiologicalProcess puromycin biosynthetic process The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger. go-plus.json http://purl.obolibrary.org/obo/GO_0043638 CHEBI:78040 biolink:ChemicalSubstance 13(S)-HPODE methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_78040 chebi_ph7_3 GO:0043637 biolink:BiologicalProcess puromycin metabolic process The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger. go-plus.json puromycin metabolism http://purl.obolibrary.org/obo/GO_0043637 GO:0043639 biolink:BiologicalProcess benzoate catabolic process The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid. go-plus.json benzoate catabolism|benzoate degradation|benzoate breakdown http://purl.obolibrary.org/obo/GO_0043639 GO:0043634 biolink:BiologicalProcess polyadenylation-dependent ncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA. go-plus.json poly(A)-dependent ncRNA catabolic process http://purl.obolibrary.org/obo/GO_0043634 CHEBI:78044 biolink:ChemicalSubstance 1-oleoyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78044 chebi_ph7_3 CHEBI:78043 biolink:ChemicalSubstance (5Z,8Z,11Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78043 chebi_ph7_3 GO:0043633 biolink:BiologicalProcess polyadenylation-dependent RNA catabolic process The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA. go-plus.json polyadenylation-dependent RNA catabolic process http://purl.obolibrary.org/obo/GO_0043633 GO:0043636 biolink:BiologicalProcess bisphenol A catabolic process The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins. go-plus.json bisphenol-A catabolic process|bisphenol-A catabolism http://purl.obolibrary.org/obo/GO_0043636 GO:0043635 biolink:BiologicalProcess methylnaphthalene catabolic process The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar. go-plus.json 1-methylnaphthalene catabolism|2-methylnaphthalene catabolism|2-methylnaphthalene catabolic process|1-methylnaphthalene catabolic process|1-MN catabolic process|2-MN catabolic process|2-MN catabolism|1-MN catabolism http://purl.obolibrary.org/obo/GO_0043635 CHEBI:78048 biolink:ChemicalSubstance 14(S)-HPDHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78048 chebi_ph7_3 CHEBI:78047 biolink:ChemicalSubstance 12(S)-HPE(8,10,14)TrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78047 chebi_ph7_3 CHEBI:78046 biolink:ChemicalSubstance 12(S)-HPE(5,8,10)TrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78046 chebi_ph7_3 CHEBI:20702 biolink:ChemicalSubstance 2-aminopurines go-plus.json http://purl.obolibrary.org/obo/CHEBI_20702 CHEBI:78045 biolink:ChemicalSubstance 2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78045 chebi_ph7_3 CHEBI:20706 biolink:ChemicalSubstance 6-aminopurines go-plus.json http://purl.obolibrary.org/obo/CHEBI_20706 CHEBI:78049 biolink:ChemicalSubstance octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78049 chebi_ph7_3 GO:0102380 biolink:MolecularActivity steviolbioside glucosyltransferase activity (rebaudioside B forming) Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+. MetaCyc:RXN-13516 go-plus.json http://purl.obolibrary.org/obo/GO_0102380 GO:0102382 biolink:MolecularActivity rebaudioside B glucosyltransferase activity Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+. MetaCyc:RXN-13518 go-plus.json http://purl.obolibrary.org/obo/GO_0102382 GO:0102381 biolink:MolecularActivity stevioside glucosyltransferase activity (rebaudioside A forming) Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+. MetaCyc:RXN-13517 go-plus.json http://purl.obolibrary.org/obo/GO_0102381 GO:0102384 biolink:MolecularActivity 19-O-beta-glucopyranosyl-steviol glucosyltransferase activity Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+. MetaCyc:RXN-13521 go-plus.json http://purl.obolibrary.org/obo/GO_0102384 GO:0102383 biolink:MolecularActivity steviol 19-O glucosyltransferase activity Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+. MetaCyc:RXN-13520 go-plus.json http://purl.obolibrary.org/obo/GO_0102383 GO:0102386 biolink:MolecularActivity phenylacetaldehyde reductase activity Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+. MetaCyc:RXN-13536 go-plus.json http://purl.obolibrary.org/obo/GO_0102386 GO:0102385 biolink:MolecularActivity patchoulol synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid. MetaCyc:RXN-13522 go-plus.json http://purl.obolibrary.org/obo/GO_0102385 GO:0043641 biolink:BiologicalProcess novobiocin metabolic process The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase. Wikipedia:Novobiocin go-plus.json novobiocin metabolism http://purl.obolibrary.org/obo/GO_0043641 GO:0102388 biolink:MolecularActivity UDP-N,N'-diacetylbacillosamine 2-epimerase activity Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+. RHEA:34491|EC:3.2.1.184|MetaCyc:RXN-13574 go-plus.json http://purl.obolibrary.org/obo/GO_0102388 GO:0102387 biolink:MolecularActivity 2-phenylethanol acetyltransferase activity Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A. EC:2.3.1.224|MetaCyc:RXN-13542 go-plus.json http://purl.obolibrary.org/obo/GO_0102387 GO:0043640 biolink:BiologicalProcess benzoate catabolic process via hydroxylation The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol. MetaCyc:PWY-2503 go-plus.json benzoate degradation via hydroxylation|benzoate breakdown via hydroxylation http://purl.obolibrary.org/obo/GO_0043640 GO:0043643 biolink:BiologicalProcess tetracycline metabolic process The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). go-plus.json tetracyclin metabolism|tetracycline metabolism|tetracyclin metabolic process http://purl.obolibrary.org/obo/GO_0043643 GO:0043642 biolink:BiologicalProcess novobiocin biosynthetic process The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase. Wikipedia:Novobiocin go-plus.json http://purl.obolibrary.org/obo/GO_0043642 GO:0102389 biolink:MolecularActivity polyprenol reductase activity Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol. MetaCyc:RXN-13604|EC:1.3.1.94|RHEA:34279 go-plus.json http://purl.obolibrary.org/obo/GO_0102389 GO:0043649 biolink:BiologicalProcess dicarboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. go-plus.json dicarboxylic acid breakdown|dicarboxylate catabolism|dicarboxylate catabolic process|dicarboxylic acid catabolism|dicarboxylic acid degradation http://purl.obolibrary.org/obo/GO_0043649 CHEBI:78051 biolink:ChemicalSubstance hexacosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78051 chebi_ph7_3 CHEBI:78050 biolink:ChemicalSubstance octadecatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78050 chebi_ph7_3 GO:0043648 biolink:BiologicalProcess dicarboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). go-plus.json dicarboxylic acid metabolism|dicarboxylate metabolism|dicarboxylate metabolic process http://purl.obolibrary.org/obo/GO_0043648 CHEBI:78055 biolink:ChemicalSubstance hexacosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78055 chebi_ph7_3 GO:0043645 biolink:BiologicalProcess cephalosporin metabolic process The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria. go-plus.json cephalosporin metabolism http://purl.obolibrary.org/obo/GO_0043645 CHEBI:78054 biolink:ChemicalSubstance hexacosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78054 chebi_ph7_3 GO:0043644 biolink:BiologicalProcess tetracycline biosynthetic process The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). go-plus.json tetracyclin biosynthetic process|tetracyclin biosynthesis http://purl.obolibrary.org/obo/GO_0043644 GO:0043647 biolink:BiologicalProcess inositol phosphate metabolic process The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. go-plus.json myo-inositol phosphate metabolism|myo-inositol phosphate metabolic process|inositol phosphate metabolism http://purl.obolibrary.org/obo/GO_0043647 CHEBI:78053 biolink:ChemicalSubstance docosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78053 chebi_ph7_3 CHEBI:78052 biolink:ChemicalSubstance tetracosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78052 chebi_ph7_3 GO:0043646 biolink:BiologicalProcess cephalosporin biosynthetic process The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0043646 CHEBI:19733 biolink:ChemicalSubstance (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19733 chebi_ph7_3 CHEBI:78059 biolink:ChemicalSubstance food additive carrier go-plus.json http://purl.obolibrary.org/obo/CHEBI_78059 CHEBI:20710 biolink:ChemicalSubstance 3-dehydro-6-deoxoteasterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_20710 chebi_ph7_3 CHEBI:78057 biolink:ChemicalSubstance hexacosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78057 chebi_ph7_3 CHEBI:78056 biolink:ChemicalSubstance tetracosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78056 chebi_ph7_3 CHEBI:20717 biolink:ChemicalSubstance 6-deoxotyphasterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_20717 chebi_ph7_3 GO:0102311 biolink:MolecularActivity 8-hydroxygeraniol dehydrogenase activity Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+. EC:1.1.1.324|MetaCyc:RXN-12961|RHEA:32659 go-plus.json http://purl.obolibrary.org/obo/GO_0102311 GO:0043652 biolink:BiologicalProcess engulfment of apoptotic cell The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte. go-plus.json engulfment of cell corpse|engulfment of apoptotic cell corpse http://purl.obolibrary.org/obo/GO_0043652 GO:0043651 biolink:BiologicalProcess linoleic acid metabolic process The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. Wikipedia:Linoleic_acid go-plus.json linoleic acid metabolism http://purl.obolibrary.org/obo/GO_0043651 GO:0102310 biolink:MolecularActivity dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose-forming) activity Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H. MetaCyc:RXN-12940 go-plus.json http://purl.obolibrary.org/obo/GO_0102310 GO:0043654 biolink:BiologicalProcess recognition of apoptotic cell The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis. go-plus.json recognition of apoptotic cell corpse|recognition of cell corpse|detection of apoptotic cell corpse|detection of apoptotic cell|detection of cell corpse http://purl.obolibrary.org/obo/GO_0043654 GO:0102313 biolink:MolecularActivity 1,8-cineole synthase activity Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid. MetaCyc:RXN-12980|RHEA:32543|EC:4.2.3.108 go-plus.json http://purl.obolibrary.org/obo/GO_0102313 GO:0102312 biolink:MolecularActivity 4-coumaroyl 2'-hydroxylase activity Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide. MetaCyc:RXN-12963|EC:1.14.11.62|RHEA:57868 go-plus.json http://purl.obolibrary.org/obo/GO_0102312 GO:0043653 biolink:BiologicalProcess mitochondrial fragmentation involved in apoptotic process The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form. go-plus.json mitochondrial fission during apoptosis|mitochondrial fragmentation involved in apoptosis http://purl.obolibrary.org/obo/GO_0043653 GO:0102315 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102315 GO:0043650 biolink:BiologicalProcess dicarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. go-plus.json dicarboxylic acid biosynthesis|dicarboxylic acid anabolism|dicarboxylate biosynthesis|dicarboxylate biosynthetic process|dicarboxylic acid synthesis|dicarboxylic acid formation http://purl.obolibrary.org/obo/GO_0043650 GO:0102317 biolink:MolecularActivity 4-methylaminobutyrate oxidase (demethylating) activity Catalysis of the reaction: 4-(methylamino)butyric acid + O2 + H2O <=> gamma-aminobutyric acid + formaldehyde + hydrogen peroxide. MetaCyc:RXN-13067|RHEA:33907|EC:1.5.3.19 go-plus.json http://purl.obolibrary.org/obo/GO_0102317 GO:0102316 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102316 GO:0102319 biolink:MolecularActivity 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-). EC:2.4.1.283|MetaCyc:RXN-13122|RHEA:33947 go-plus.json http://purl.obolibrary.org/obo/GO_0102319 CHEBI:78062 biolink:ChemicalSubstance octacosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78062 chebi_ph7_3 GO:0102318 biolink:MolecularActivity 2-deoxystreptamine glucosyltransferase activity Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+. RHEA:34063|EC:2.4.1.284|MetaCyc:RXN-13121 go-plus.json http://purl.obolibrary.org/obo/GO_0102318 CHEBI:78061 biolink:ChemicalSubstance tetracosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78061 chebi_ph7_3 GO:0043659 biolink:CellularComponent symbiosome A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane). go-plus.json http://purl.obolibrary.org/obo/GO_0043659 PR:000005388 biolink:Protein glycoprotein hormones alpha chain A protein that is a translation product of the human CGA gene or a 1:1 ortholog thereof. go-plus.json TSH-alpha|choriogonadotropin alpha chain|CG-alpha|luteinizing hormone alpha chain|LSH-alpha|lutropin alpha chain|FSH-alpha|thyroid-stimulating hormone alpha chain|anterior pituitary glycoprotein hormones common subunit alpha|follicle-stimulating hormone alpha chain|thyrotropin alpha chain|chorionic gonadotrophin subunit alpha|follitropin alpha chain|CGA http://purl.obolibrary.org/obo/PR_000005388 CHEBI:78060 biolink:ChemicalSubstance docosahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78060 chebi_ph7_3 GO:0043656 biolink:CellularComponent host intracellular region That space within the plasma membrane of a host cell. go-plus.json intracellular region of host|host intracellular http://purl.obolibrary.org/obo/GO_0043656 GO:0043655 biolink:CellularComponent host extracellular space The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream. go-plus.json extracellular space of host|host extracellular space http://purl.obolibrary.org/obo/GO_0043655 GO:0043658 biolink:CellularComponent host symbiosome A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043658 GO:0043657 biolink:CellularComponent host cell A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0043657 CHEBI:78063 biolink:ChemicalSubstance octacosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78063 chebi_ph7_3 CHEBI:78069 biolink:ChemicalSubstance docosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78069 chebi_ph7_3 CHEBI:78068 biolink:ChemicalSubstance tetracosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78068 chebi_ph7_3 GO:0102320 biolink:MolecularActivity 1,8-cineole 2-exo-monooxygenase activity Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O. RHEA:32895|EC:1.14.14.56|MetaCyc:RXN-13133 go-plus.json http://purl.obolibrary.org/obo/GO_0102320 GO:0043663 biolink:CellularComponent host bacteroid-containing symbiosome A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043663 GO:0102322 biolink:MolecularActivity 2-propylphenol monooxygenase activity Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD. MetaCyc:RXN-13151|RHEA:63524 go-plus.json http://purl.obolibrary.org/obo/GO_0102322 GO:0102321 biolink:MolecularActivity 2,2'-hydroxybiphenyl monooxygenase activity Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD. MetaCyc:MONOMER-17239|EC:1.14.13.44|RHEA:63512 go-plus.json http://purl.obolibrary.org/obo/GO_0102321 GO:0043662 biolink:CellularComponent peribacteroid fluid The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome. go-plus.json http://purl.obolibrary.org/obo/GO_0043662 GO:0043665 biolink:CellularComponent host peribacteroid fluid The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0043665 GO:0102324 biolink:MolecularActivity 2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+. MetaCyc:RXN-13157 go-plus.json http://purl.obolibrary.org/obo/GO_0102324 GO:0102323 biolink:MolecularActivity 2-isopropylphenol monooxygenase activity Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD. RHEA:63520|MetaCyc:RXN-13152 go-plus.json http://purl.obolibrary.org/obo/GO_0102323 GO:0043664 biolink:CellularComponent host peribacteroid membrane A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells). go-plus.json http://purl.obolibrary.org/obo/GO_0043664 GO:0102326 biolink:MolecularActivity 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate hydrolase activity Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+. MetaCyc:RXN-13171 go-plus.json http://purl.obolibrary.org/obo/GO_0102326 CHEBI:78080 biolink:ChemicalSubstance triacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78080 chebi_ph7_3 GO:0102325 biolink:MolecularActivity 2,2',3-trihydroxybiphenyl monooxygenase activity Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ <=> 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O. MetaCyc:RXN-13169|RHEA:63516 go-plus.json http://purl.obolibrary.org/obo/GO_0102325 GO:0043661 biolink:CellularComponent peribacteroid membrane A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells). go-plus.json http://purl.obolibrary.org/obo/GO_0043661 GO:0102328 biolink:MolecularActivity 3-oxoacid decarboxylase activity Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone. MetaCyc:RXN-13248 go-plus.json http://purl.obolibrary.org/obo/GO_0102328 GO:0043660 biolink:CellularComponent bacteroid-containing symbiosome A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants. go-plus.json http://purl.obolibrary.org/obo/GO_0043660 GO:0102327 biolink:MolecularActivity 3-oxoacyl-CoA hydrolase activity Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid. MetaCyc:RXN-13247 go-plus.json http://purl.obolibrary.org/obo/GO_0102327 CHEBI:78073 biolink:ChemicalSubstance icosadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78073 chebi_ph7_3 CHEBI:78072 biolink:ChemicalSubstance icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78072 chebi_ph7_3 GO:0102329 biolink:MolecularActivity hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase activity Catalysis of the reaction: 16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA + NADP <=> hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA + NADPH + H+. MetaCyc:RXN-13251 go-plus.json http://purl.obolibrary.org/obo/GO_0102329 CHEBI:78070 biolink:ChemicalSubstance 10(R)-HPO(6,8,12)TrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78070 chebi_ph7_3 GO:0043667 biolink:CellularComponent pollen wall The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine. go-plus.json microspore wall http://purl.obolibrary.org/obo/GO_0043667 CHEBI:78076 biolink:ChemicalSubstance docosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78076 chebi_ph7_3 GO:0043666 biolink:BiologicalProcess regulation of phosphoprotein phosphatase activity Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein. go-plus.json regulation of protein phosphatase type 2A activity|regulation of protein phosphatase type 2B activity|regulation of protein phosphatase 3 activity|regulation of calcineurin activity|regulation of protein phosphatase type 2 activity http://purl.obolibrary.org/obo/GO_0043666 CHEBI:78075 biolink:ChemicalSubstance icosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78075 chebi_ph7_3 GO:0043669 biolink:CellularComponent ectexine The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections. go-plus.json http://purl.obolibrary.org/obo/GO_0043669 GO:0043668 biolink:CellularComponent exine The outer layer of the pollen grain wall which is composed primarily of sporopollenin. go-plus.json http://purl.obolibrary.org/obo/GO_0043668 CHEBI:78079 biolink:ChemicalSubstance triacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78079 chebi_ph7_3 CHEBI:78078 biolink:ChemicalSubstance 12-HPEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78078 chebi_ph7_3 GO:0102331 biolink:MolecularActivity heptadecanoyl-[acp] elongase/decarboxylase activity Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. MetaCyc:RXN-13259 go-plus.json http://purl.obolibrary.org/obo/GO_0102331 GO:0102330 biolink:MolecularActivity palmitoyl-[acp] elongase/decarboxylase activity Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. MetaCyc:RXN-13258 go-plus.json http://purl.obolibrary.org/obo/GO_0102330 GO:0102333 biolink:MolecularActivity stearoyl-[acp] elongase/decarboxylase activity Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. MetaCyc:RXN-13261 go-plus.json http://purl.obolibrary.org/obo/GO_0102333 GO:0043674 biolink:CellularComponent columella A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella). go-plus.json sexine 1 http://purl.obolibrary.org/obo/GO_0043674 GO:0043673 biolink:CellularComponent sexine The outer, sculptured layer of the exine, which lies above the nexine. go-plus.json http://purl.obolibrary.org/obo/GO_0043673 GO:0102332 biolink:MolecularActivity fatty-acyl-[acp] elongase/decarboxylase activity Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor. MetaCyc:RXN-13260 go-plus.json http://purl.obolibrary.org/obo/GO_0102332 GO:0102335 biolink:MolecularActivity N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+. EC:2.4.1.290|MetaCyc:RXN-13274|RHEA:34511 go-plus.json http://purl.obolibrary.org/obo/GO_0102335 GO:0043676 biolink:CellularComponent tectum The layer of sexine which forms a roof over the columella, granules or other infratectal elements. go-plus.json sexine 2 http://purl.obolibrary.org/obo/GO_0043676 GO:0102334 biolink:MolecularActivity N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP. MetaCyc:RXN-13269|RHEA:34515|EC:2.7.8.36 go-plus.json http://purl.obolibrary.org/obo/GO_0102334 GO:0043675 biolink:CellularComponent sculpture element The third layer of the sexine. go-plus.json http://purl.obolibrary.org/obo/GO_0043675 GO:0043670 biolink:CellularComponent foot layer The inner layer of the ectexine. go-plus.json nexine 1 http://purl.obolibrary.org/obo/GO_0043670 GO:0102337 biolink:MolecularActivity 3-oxo-cerotoyl-CoA synthase activity Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A. MetaCyc:RXN-13296|RHEA:36515 go-plus.json http://purl.obolibrary.org/obo/GO_0102337 CHEBI:78091 biolink:ChemicalSubstance hexatriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78091 chebi_ph7_3 GO:0102336 biolink:MolecularActivity 3-oxo-arachidoyl-CoA synthase activity Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A. MetaCyc:RXN-13294|RHEA:35319 go-plus.json http://purl.obolibrary.org/obo/GO_0102336 CHEBI:78090 biolink:ChemicalSubstance 1,2-dipalmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78090 chebi_ph7_3 GO:0043672 biolink:CellularComponent nexine The inner, non-sculptured part of the exine which lies below the sexine. go-plus.json http://purl.obolibrary.org/obo/GO_0043672 GO:0102339 biolink:MolecularActivity 3-oxo-arachidoyl-CoA reductase activity Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+. EC:1.1.1.330|MetaCyc:RXN-13298 go-plus.json http://purl.obolibrary.org/obo/GO_0102339 GO:0102338 biolink:MolecularActivity 3-oxo-lignoceronyl-CoA synthase activity Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A. MetaCyc:RXN-13297|RHEA:36507 go-plus.json http://purl.obolibrary.org/obo/GO_0102338 GO:0043671 biolink:CellularComponent endexine The inner part of the exine, which stains. go-plus.json http://purl.obolibrary.org/obo/GO_0043671 CHEBI:78084 biolink:ChemicalSubstance hepoxilin B3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78084 chebi_ph7_3 CHEBI:78083 biolink:ChemicalSubstance dotriacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78083 chebi_ph7_3 CHEBI:78082 biolink:ChemicalSubstance dotriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78082 chebi_ph7_3 CHEBI:78081 biolink:ChemicalSubstance dotriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78081 chebi_ph7_3 GO:0043678 biolink:CellularComponent intine The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0043678 CHEBI:78088 biolink:ChemicalSubstance tetratriacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78088 chebi_ph7_3 GO:0043677 biolink:CellularComponent obsolete germination pore OBSOLETE. A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location. Wikipedia:Germ_pore go-plus.json germ pore http://purl.obolibrary.org/obo/GO_0043677 CHEBI:78087 biolink:ChemicalSubstance tetratriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78087 chebi_ph7_3 CHEBI:19702 biolink:ChemicalSubstance N(2)-methylguanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_19702 chebi_ph7_3 CHEBI:78086 biolink:ChemicalSubstance tetratriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78086 chebi_ph7_3 GO:0043679 biolink:CellularComponent axon terminus Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it. NIF_Subcellular:nlx_subcell_20090512 go-plus.json axon terminal specialization|nerve ending|axon terminal http://purl.obolibrary.org/obo/GO_0043679 CHEBI:78085 biolink:ChemicalSubstance N-hexadecanoylphosphatidylethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78085 chebi_ph7_3 CHEBI:78089 biolink:ChemicalSubstance hexatriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78089 chebi_ph7_3 GO:0102340 biolink:MolecularActivity 3-oxo-behenoyl-CoA reductase activity Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+. EC:1.1.1.330|MetaCyc:RXN-13299 go-plus.json http://purl.obolibrary.org/obo/GO_0102340 GO:0102342 biolink:MolecularActivity 3-oxo-cerotoyl-CoA reductase activity Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA + NADP <=> 3-oxohexacosanoyl-CoA + NADPH + H+. EC:1.1.1.330|MetaCyc:RXN-13301 go-plus.json http://purl.obolibrary.org/obo/GO_0102342 GO:0102341 biolink:MolecularActivity 3-oxo-lignoceroyl-CoA reductase activity Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+. EC:1.1.1.330|MetaCyc:RXN-13300 go-plus.json http://purl.obolibrary.org/obo/GO_0102341 GO:0102344 biolink:MolecularActivity 3-hydroxy-behenoyl-CoA dehydratase activity Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O. EC:4.2.1.134|MetaCyc:RXN-13303 go-plus.json http://purl.obolibrary.org/obo/GO_0102344 GO:0043685 biolink:BiologicalProcess conversion of glutamyl-tRNA to glutaminyl-tRNA The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0043685 GO:0043684 biolink:CellularComponent type IV secretion system complex A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s). go-plus.json type IV protein secretion system complex|T4SS complex http://purl.obolibrary.org/obo/GO_0043684 GO:0102343 biolink:MolecularActivity 3-hydroxy-arachidoyl-CoA dehydratase activity Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA <=> trans-2-icosenoyl-CoA + H2O. EC:4.2.1.134|MetaCyc:RXN-13302 go-plus.json http://purl.obolibrary.org/obo/GO_0102343 GO:0043687 biolink:BiologicalProcess post-translational protein modification The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. Wikipedia:Posttranslational_modification go-plus.json post-translational modification|post-translational amino acid modification|PTM|posttranslational modification|posttranslational protein modification|posttranslational amino acid modification http://purl.obolibrary.org/obo/GO_0043687 GO:0102346 biolink:MolecularActivity 3-hydroxy-cerotoyl-CoA dehydratase activity Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA(4-) <=> trans-2-hexacosenoyl-CoA(4-) + H2O. MetaCyc:RXN-13305 go-plus.json http://purl.obolibrary.org/obo/GO_0102346 GO:0043686 biolink:BiologicalProcess co-translational protein modification The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome. go-plus.json cotranslational amino acid modification|cotranslational modification|cotranslational protein modification|co-translational modification|co-translational amino acid modification http://purl.obolibrary.org/obo/GO_0043686 GO:0102345 biolink:MolecularActivity 3-hydroxy-lignoceroyl-CoA dehydratase activity Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O. EC:4.2.1.134|MetaCyc:RXN-13304 go-plus.json http://purl.obolibrary.org/obo/GO_0102345 GO:0102348 biolink:MolecularActivity trans-docosan-2-enoyl-CoA reductase activity Catalysis of the reaction: behenoyl-CoA + NADP <=> trans-2-docosenoyl-CoA + NADPH + H+. MetaCyc:RXN-13307 go-plus.json http://purl.obolibrary.org/obo/GO_0102348 GO:0043681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043681 GO:0043680 biolink:CellularComponent filiform apparatus A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells. go-plus.json http://purl.obolibrary.org/obo/GO_0043680 GO:0102347 biolink:MolecularActivity trans-arachidon-2-enoyl-CoA reductase activity Catalysis of the reaction: icosanoyl-CoA(4-) + NADP(3-) <=> trans-2-icosenoyl-CoA(4-) + NADPH(4-) + H+. MetaCyc:RXN-13306 go-plus.json http://purl.obolibrary.org/obo/GO_0102347 GO:0043683 biolink:BiologicalProcess type IV pilus assembly The assembly from its constituent parts of a type IV pilus. go-plus.json type IV fimbrium biogenesis|type IV fimbriae assembly|type IV fimbria assembly|type IV fimbriae biogenesis|type IV fimbrial assembly|type IV fimbria biogenesis|type IV fimbrial biogenesis|type IV pilus biogenesis|type IV fimbrium assembly http://purl.obolibrary.org/obo/GO_0043683 GO:0043682 biolink:MolecularActivity P-type divalent copper transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out). Reactome:R-HSA-936895|Reactome:R-HSA-936802|Reactome:R-HSA-3697838|MetaCyc:3.6.3.4-RXN|EC:7.2.2.9|Reactome:R-HSA-6803545|RHEA:10376 go-plus.json Cu2+-exporting ATPase activity|copper-translocating P-type ATPase activity|copper-transporting ATPase activity|copper-exporting ATPase activity|copper exporting ATPase activity|Cu(2+)-exporting ATPase activity|copper transmembrane transporter activity, phosphorylative mechanism http://purl.obolibrary.org/obo/GO_0043682 GO:0102349 biolink:MolecularActivity trans-lignocero-2-enoyl-CoA reductase activity Catalysis of the reaction: tetracosanoyl-CoA + NADP <=> trans-2-tetracosenoyl-CoA + NADPH + H+. MetaCyc:RXN-13308 go-plus.json http://purl.obolibrary.org/obo/GO_0102349 CHEBI:78095 biolink:ChemicalSubstance hexadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78095 chebi_ph7_3 CHEBI:78094 biolink:ChemicalSubstance octatriacontapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78094 chebi_ph7_3 CHEBI:78093 biolink:ChemicalSubstance octatriacontatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78093 chebi_ph7_3 CHEBI:78092 biolink:ChemicalSubstance hexatriacontahexaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78092 chebi_ph7_3 GO:0043689 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043689 CHEBI:78099 biolink:ChemicalSubstance trioxilin B3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78099 chebi_ph7_3 GO:0043688 biolink:BiologicalProcess conversion of aspartyl-tRNA to asparaginyl-tRNA The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0043688 CHEBI:78098 biolink:ChemicalSubstance 1-palmitylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78098 CHEBI:78097 biolink:ChemicalSubstance N-palmitoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78097 chebi_ph7_3 CHEBI:78096 biolink:ChemicalSubstance hexadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78096 chebi_ph7_3 CHEBI:20680 biolink:ChemicalSubstance 6,7-dihydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_20680 chebi_ph7_3 CHEBI:29019 biolink:ChemicalSubstance nonanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29019 CHEBI:68623 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-mannosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68623 chebi_ph7_3 CHEBI:29014 biolink:ChemicalSubstance cordycepin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29014 chebi_ph7_3 CHEBI:29017 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29017 CHEBI:68625 biolink:ChemicalSubstance valerena-4,7(11)-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_68625 chebi_ph7_3 CHEBI:68624 biolink:ChemicalSubstance cis-abienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_68624 chebi_ph7_3 CHEBI:29016 biolink:ChemicalSubstance arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29016 CHEBI:29010 biolink:ChemicalSubstance 2'-aminobiphenyl-2,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29010 chebi_ph7_3 CHEBI:29013 biolink:ChemicalSubstance fusidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29013 PR:000019919 biolink:Protein fibronectin proteolytic cleavage product A fibronectin that has been processed by proteolytic cleavage. go-plus.json FN1/ClvPrd http://purl.obolibrary.org/obo/PR_000019919 UBERON:0005472 biolink:AnatomicalEntity right vitelline vein A vitelline vein that is in the right side of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005472 UBERON:0005470 biolink:AnatomicalEntity right umbilical artery go-plus.json embryonic right umbilical artery http://purl.obolibrary.org/obo/UBERON_0005470 CHEBI:30001 biolink:ChemicalSubstance D-selenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30001 UBERON:0005478 biolink:AnatomicalEntity sulcus limitans of neural tube A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. go-plus.json sulcus limitans|neural tube lateral wall sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 UBERON:0005476 biolink:AnatomicalEntity spinal nerve trunk trunk part of spinal nerve, where dorsal and ventral roots meet to form the spinal nerve, before branching off to dorsal and ventral rami. go-plus.json spinal nerve (trunk)|trunk of spinal nerve|spinal neural trunk http://purl.obolibrary.org/obo/UBERON_0005476 CHEBI:19680 biolink:ChemicalSubstance 2-methylacetoacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19680 chebi_ph7_3 CHEBI:30018 biolink:ChemicalSubstance D-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_30018 chebi_ph7_3 CHEBI:29028 biolink:ChemicalSubstance glucobrassicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29028 CHEBI:68636 biolink:ChemicalSubstance p-hydroxyphenylbut-3-ene-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_68636 chebi_ph7_3 CHEBI:44642 biolink:ChemicalSubstance 2'-O-methyluridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44642 CHEBI:29021 biolink:ChemicalSubstance hexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_29021 chebi_ph7_3 CHEBI:29024 biolink:ChemicalSubstance 4-methyl-3-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29024 UBERON:0005463 biolink:AnatomicalEntity subcapsular sinus of lymph node A space between the capsule and the cortex which allows the free movement of lymphatic fluid and so contains a sparsity of lymphocytes. It is continuous with the similar lymph sinuses that flank the trabeculae. go-plus.json marginal sinus|marginal sinus of lymph node|subcapsular sinus|lymph node subcortical sinus|lymph sinus|lymph path http://purl.obolibrary.org/obo/UBERON_0005463 CHEBI:29031 biolink:ChemicalSubstance phosphinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29031 UBERON:0005461 biolink:AnatomicalEntity levator scapulae muscle An axial muscle that originates in the cervical vertebraae inserts on the scapula. go-plus.json levator scapulæ|levator scapula|musculus levator scapulae|levator scapulae|levator scapulae muscle http://purl.obolibrary.org/obo/UBERON_0005461 UBERON:0005460 biolink:AnatomicalEntity left vitelline vein A vitelline vein that is in the left side of a multicellular organism. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005460 CHEBI:30014 biolink:ChemicalSubstance D-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_30014 chebi_ph7_3 CHEBI:30013 biolink:ChemicalSubstance L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_30013 chebi_ph7_3 UBERON:0005469 biolink:AnatomicalEntity right thymus lobe A thymus lobe that is in the right side of a thymus. go-plus.json right thymic lobe|right lobe of thymus http://purl.obolibrary.org/obo/UBERON_0005469 CHEBI:30011 biolink:ChemicalSubstance L-glutamine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_30011 chebi_ph7_3 CHEBI:19672 biolink:ChemicalSubstance 4-oxohex-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19672 CHEBI:20664 biolink:ChemicalSubstance 5beta-cholane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20664 chebi_ph7_3 CHEBI:68645 biolink:ChemicalSubstance 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_68645 chebi_ph7_3 UBERON:6057001 biolink:AnatomicalEntity insect anterior-posterior subdivision of organism go-plus.json http://purl.obolibrary.org/obo/UBERON_6057001 UBERON:0005452 biolink:AnatomicalEntity hepatic cord A three-dimensional arrangement formed by plates of hepatocytes, usually one cell thick, that radiates from the center of the liver lobule; hepatic laminae are highly branched, irregular structures bordered by endothelial lined vascular spaces called hepatic sinusoids. go-plus.json liver cell plate|hepatic plate|hepatic lamina|hepatic laminae|lamina hepatica http://purl.obolibrary.org/obo/UBERON_0005452 UBERON:0005451 biolink:AnatomicalEntity segment of manus A segment of autopod that is part of a manus. go-plus.json regio manus|segment of hand|subdivision of hand|hand subdivision|hand region http://purl.obolibrary.org/obo/UBERON_0005451 CHEBI:44639 biolink:ChemicalSubstance tert-butylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44639 CHEBI:68649 biolink:ChemicalSubstance pentalenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68649 chebi_ph7_3 CHEBI:44638 biolink:ChemicalSubstance 2'-O-methylguanosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44638 UBERON:0005458 biolink:AnatomicalEntity left umbilical artery go-plus.json embryonic left umbilical artery http://purl.obolibrary.org/obo/UBERON_0005458 UBERON:0005457 biolink:AnatomicalEntity left thymus lobe A thymus lobe that is in the left side of a thymus. go-plus.json left lobe of thymus|left thymic lobe http://purl.obolibrary.org/obo/UBERON_0005457 UBERON:0005456 biolink:AnatomicalEntity jugular foramen The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side go-plus.json Posterior lacerate foramen|foramen jugulare http://purl.obolibrary.org/obo/UBERON_0005456 CHEBI:20670 biolink:ChemicalSubstance 5beta-estrane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20670 chebi_ph7_3 CHEBI:68650 biolink:ChemicalSubstance 1-deoxypentalenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68650 chebi_ph7_3 CHEBI:20674 biolink:ChemicalSubstance 5beta-pregnane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20674 chebi_ph7_3 CHEBI:29009 biolink:ChemicalSubstance N(tele)-methylhistamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29009 CHEBI:29003 biolink:ChemicalSubstance L-citramalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29003 CHEBI:68655 biolink:ChemicalSubstance Delta(6)-protoilludene go-plus.json http://purl.obolibrary.org/obo/CHEBI_68655 chebi_ph7_3 CHEBI:68658 biolink:ChemicalSubstance (+)-epi-alpha-bisabolol go-plus.json http://purl.obolibrary.org/obo/CHEBI_68658 chebi_ph7_3 CHEBI:29006 biolink:ChemicalSubstance N-acetyl-4-O-acetylneuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29006 chebi_ph7_3 CHEBI:29005 biolink:ChemicalSubstance cyclohexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_29005 chebi_ph7_3 CHEBI:68652 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68652 chebi_ph7_3 CHEBI:68651 biolink:ChemicalSubstance alpha-D-GalNAc-(1->4)-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68651 chebi_ph7_3 CHEBI:68654 biolink:ChemicalSubstance [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68654 chebi_ph7_3 CHEBI:29002 biolink:ChemicalSubstance (S)-propane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29002 chebi_ph7_3 CHEBI:29001 biolink:ChemicalSubstance (3R)-3-isopropenyl-6-oxoheptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29001 chebi_ph7_3 CHEBI:68653 biolink:ChemicalSubstance [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68653 chebi_ph7_3 UBERON:0005446 biolink:AnatomicalEntity foramen rotundum The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa. go-plus.json round foramen|foramen rotundum ossis sphenoidalis|foramen rotundum of the skull http://purl.obolibrary.org/obo/UBERON_0005446 UBERON:0005445 biolink:AnatomicalEntity segment of pes A segment of autopod that is part of a pes. go-plus.json segment of foot|subdivision of foot|foot subdivision|foot region|regio pedis http://purl.obolibrary.org/obo/UBERON_0005445 GO:0102391 biolink:MolecularActivity decanoate-CoA ligase activity Catalysis of the reaction: ATP + decanoate + CoA = AMP + diphosphate + decanoyl-CoA. RHEA:33627|MetaCyc:RXN-13614 go-plus.json http://purl.obolibrary.org/obo/GO_0102391 GO:0102390 biolink:MolecularActivity mycophenolic acid acyl-glucuronide esterase activity Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate. EC:3.1.1.93|RHEA:34179|MetaCyc:RXN-13605 go-plus.json http://purl.obolibrary.org/obo/GO_0102390 GO:0102393 biolink:MolecularActivity decanoyl-[acp] 2-dehydrogenase activity Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein <=> FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF. MetaCyc:RXN-13624 go-plus.json http://purl.obolibrary.org/obo/GO_0102393 GO:0102392 biolink:MolecularActivity decanoate-[HmqF protein] ligase activity Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein. MetaCyc:RXN-13623 go-plus.json http://purl.obolibrary.org/obo/GO_0102392 GO:0102395 biolink:MolecularActivity 9-cis-beta-carotene 9',10'-cleavage oxygenase activity Catalysis of the reaction: 9-cis-beta-carotene + O2 <=> 9-cis-10'-apo-beta-carotenal + beta-ionone. RHEA:34399|EC:1.13.11.68|MetaCyc:RXN-13642 go-plus.json http://purl.obolibrary.org/obo/GO_0102395 GO:0102394 biolink:MolecularActivity 4-hydroxy-L-isoleucine dehydrogenase activity Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+. MetaCyc:RXN-13637 go-plus.json http://purl.obolibrary.org/obo/GO_0102394 CHEBI:20640 biolink:ChemicalSubstance 5alpha-campestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20640 chebi_ph7_3 CHEBI:20642 biolink:ChemicalSubstance 5alpha-cholane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20642 chebi_ph7_3 GO:0102396 biolink:MolecularActivity 9-cis-10'-apo-beta-carotenal cleavage oxygenase activity Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal. RHEA:34403|EC:1.13.11.69|MetaCyc:RXN-13643 go-plus.json http://purl.obolibrary.org/obo/GO_0102396 GO:0102399 biolink:MolecularActivity dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+. MetaCyc:RXN-13658 go-plus.json http://purl.obolibrary.org/obo/GO_0102399 CHEBI:68667 biolink:ChemicalSubstance (E)-2-epi-beta-caryophyllene go-plus.json http://purl.obolibrary.org/obo/CHEBI_68667 chebi_ph7_3 CHEBI:68666 biolink:ChemicalSubstance (-)-alpha-isocomene go-plus.json http://purl.obolibrary.org/obo/CHEBI_68666 chebi_ph7_3 GO:0102398 biolink:MolecularActivity dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+. MetaCyc:RXN-13657 go-plus.json http://purl.obolibrary.org/obo/GO_0102398 CHEBI:68669 biolink:ChemicalSubstance N,N-diacetyllegionaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68669 chebi_ph7_3 PR:000019959 biolink:Protein galanin proteolytic cleavage product A galanin that has been processed by proteolytic cleavage. go-plus.json GAL/ClvPrd http://purl.obolibrary.org/obo/PR_000019959 CHEBI:68668 biolink:ChemicalSubstance legionaminate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68668 chebi_ph7_3 CHEBI:68665 biolink:ChemicalSubstance pentalenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68665 CHEBI:19641 biolink:ChemicalSubstance 2-hydroxyisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19641 chebi_ph7_3 CHEBI:68670 biolink:ChemicalSubstance CMP-N,N-diacetyllegionaminate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68670 chebi_ph7_3 CHEBI:68672 biolink:ChemicalSubstance N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68672 chebi_ph7_3 CHEBI:68671 biolink:ChemicalSubstance CMP-N-acyl-beta-neuraminate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68671 chebi_ph7_3 CHEBI:20652 biolink:ChemicalSubstance 5alpha-ergostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20652 chebi_ph7_3 CHEBI:68678 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68678 CHEBI:68677 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_68677 CHEBI:68679 biolink:ChemicalSubstance dTDP-6-deoxy-beta-L-talose go-plus.json http://purl.obolibrary.org/obo/CHEBI_68679 CHEBI:68676 biolink:ChemicalSubstance legionaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68676 CHEBI:68675 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68675 chebi_ph7_3 CHEBI:20656 biolink:ChemicalSubstance 5alpha-pregnane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20656 chebi_ph7_3 CHEBI:20659 biolink:ChemicalSubstance 5beta-androstane go-plus.json http://purl.obolibrary.org/obo/CHEBI_20659 chebi_ph7_3 CHEBI:68681 biolink:ChemicalSubstance UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68681 CHEBI:68683 biolink:ChemicalSubstance CMP-N,N-diacetyllegionaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68683 CHEBI:68682 biolink:ChemicalSubstance N,N-diacetyllegionaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68682 CHEBI:68689 biolink:ChemicalSubstance 5-phospho-alpha-D-ribose cyclic-1,2-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68689 CHEBI:68688 biolink:ChemicalSubstance alpha-D-ribose 1,5-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68688 chebi_ph7_3 CHEBI:68685 biolink:ChemicalSubstance alpha-D-ribose 1-methylphosphonate 5-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68685 CHEBI:68684 biolink:ChemicalSubstance methylphosphonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68684 chebi_ph7_3 CHEBI:68687 biolink:ChemicalSubstance 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68687 chebi_ph7_3 CHEBI:68686 biolink:ChemicalSubstance alpha-D-ribose 1-methylphosphonate 5-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68686 chebi_ph7_3 UBERON:0005497 biolink:AnatomicalEntity non-neural ectoderm go-plus.json ventral ectoderm|surface ectoderm|non neural ectoderm|epithelial ectoderm|epidermal ectoderm http://purl.obolibrary.org/obo/UBERON_0005497 UBERON:0005496 biolink:AnatomicalEntity neural tube lateral wall Portion of tissue on the side of the lumen of the neural tube. go-plus.json lateral wall neural tube http://purl.obolibrary.org/obo/UBERON_0005496 UBERON:0005491 biolink:AnatomicalEntity glossopharyngeal neural crest Cranial neural crest which gives rise to the glossopharyngeal ganglion. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005491 CHEBI:78004 biolink:ChemicalSubstance food bulking agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_78004 CHEBI:78003 biolink:ChemicalSubstance food bleaching agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_78003 CHEBI:78001 biolink:ChemicalSubstance N-dodecanoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78001 chebi_ph7_3 UBERON:0005499 biolink:AnatomicalEntity rhombomere 1 Hindbrain segment or neuromere 1. go-plus.json r1 http://purl.obolibrary.org/obo/UBERON_0005499 CHEBI:20629 biolink:ChemicalSubstance 5-phosphoribosyl-ATP go-plus.json http://purl.obolibrary.org/obo/CHEBI_20629 UBERON:0005498 biolink:AnatomicalEntity primitive heart tube Multi-tissue structure that arises from the heart rudiment and will become the heart tube. go-plus.json early primitive heart tube|primitive heart tube http://purl.obolibrary.org/obo/UBERON_0005498 CHEBI:19660 biolink:ChemicalSubstance 2-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19660 CL:0019031 biolink:Cell intestine goblet cell Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. go-plus.json intestinal goblet cell http://purl.obolibrary.org/obo/CL_0019031 GO:0043605 biolink:BiologicalProcess cellular amide catabolic process The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. go-plus.json http://purl.obolibrary.org/obo/GO_0043605 GO:0043604 biolink:BiologicalProcess amide biosynthetic process The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. go-plus.json http://purl.obolibrary.org/obo/GO_0043604 UBERON:0005484 biolink:AnatomicalEntity tricuspid valve leaflet A valve leaflet that is part of a tricuspid valve. go-plus.json tricuspid valve leaflet|leaflet of tricuspid valve|tricuspid valve leaflets|tricuspid valvular leaflet http://purl.obolibrary.org/obo/UBERON_0005484 GO:0043607 biolink:BiologicalProcess formamide biosynthetic process The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0043607 GO:0043606 biolink:BiologicalProcess formamide metabolic process The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid. go-plus.json formamide metabolism http://purl.obolibrary.org/obo/GO_0043606 UBERON:0005483 biolink:AnatomicalEntity thymus lobe Either of the two lateral lobes that constitute the thymus. go-plus.json lateral lobe of thymus|lobe of thymus http://purl.obolibrary.org/obo/UBERON_0005483 GO:0043601 biolink:CellularComponent nuclear replisome A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0043601 GO:0043600 biolink:CellularComponent cytoplasmic replisome A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins. go-plus.json prokaryotic replisome http://purl.obolibrary.org/obo/GO_0043600 GO:0043603 biolink:BiologicalProcess cellular amide metabolic process The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. go-plus.json amide metabolism http://purl.obolibrary.org/obo/GO_0043603 goslim_pir GO:0043602 biolink:BiologicalProcess nitrate catabolic process The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid. go-plus.json nitrate disassimilation|nitrate dissimilation http://purl.obolibrary.org/obo/GO_0043602 CHEBI:78013 biolink:ChemicalSubstance linoleic acid hydroperoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_78013 GO:0043609 biolink:BiologicalProcess regulation of carbon utilization Any process that modulates the frequency, rate, or extent of carbon utilization. go-plus.json http://purl.obolibrary.org/obo/GO_0043609 GO:0043608 biolink:BiologicalProcess formamide catabolic process The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0043608 CHEBI:78017 biolink:ChemicalSubstance food propellant go-plus.json http://purl.obolibrary.org/obo/CHEBI_78017 UBERON:0005487 biolink:AnatomicalEntity vitelline vein the paired veins that carry blood from the yolk sac back to the embryo go-plus.json vein of omphalomesenteric system|embryonic vitelline vein|vena vitellina|vitelline veins|vascular vitelline network|omphalomesenteric vein http://purl.obolibrary.org/obo/UBERON_0005487 CHEBI:78016 biolink:ChemicalSubstance food gelling agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_78016 GO:0004008 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004008 GO:0004007 biolink:MolecularActivity obsolete heavy metal-exporting ATPase activity OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate. go-plus.json heavy metal-exporting ATPase activity http://purl.obolibrary.org/obo/GO_0004007 GO:0004009 biolink:MolecularActivity obsolete ATP-binding cassette (ABC) transporter activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ATP-binding cassette (ABC) transporter activity http://purl.obolibrary.org/obo/GO_0004009 GO:0004004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004004 GO:0004003 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004003 GO:0004006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004006 GO:0004005 biolink:MolecularActivity obsolete plasma membrane cation-transporting ATPase OBSOLETE. (Was not defined before being made obsolete). go-plus.json plasma membrane cation-transporting ATPase http://purl.obolibrary.org/obo/GO_0004005 GO:0004000 biolink:MolecularActivity adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3. Reactome:R-HSA-2161195|Reactome:R-HSA-2161187|Reactome:R-HSA-74241|Reactome:R-HSA-5693346|RHEA:24408|EC:3.5.4.4|MetaCyc:ADENODEAMIN-RXN go-plus.json adenosine deaminase reaction|adenosine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0004000 GO:0004002 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004002 GO:0004001 biolink:MolecularActivity adenosine kinase activity Catalysis of the reaction: ATP + adenosine = ADP + AMP. RHEA:20824|MetaCyc:ADENOSINE-KINASE-RXN|Reactome:R-HSA-109624|EC:2.7.1.20 go-plus.json adenosine 5-phosphotransferase activity|ATP:adenosine 5'-phosphotransferase activity|adenosine kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0004001 GO:0018649 biolink:MolecularActivity tetrahydrofuran hydroxylase activity Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran. EC:1.14.13.-|UM-BBD_reactionID:r0017 go-plus.json http://purl.obolibrary.org/obo/GO_0018649 GO:0018648 biolink:MolecularActivity methanesulfonate monooxygenase activity Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O. MetaCyc:RXN-9770|RHEA:26077|EC:1.14.13.111 go-plus.json mesylate monooxygenase activity|methanesulphonic acid monooxygenase activity|methanesulfonate,NADH:oxygen oxidoreductase activity|MSAMO activity|methanesulfonate,FMNH2:oxygen oxidoreductase activity|MSA monooxygenase activity|methanesulfonic acid monooxygenase activity http://purl.obolibrary.org/obo/GO_0018648 CHEBI:30081 biolink:ChemicalSubstance dicarbide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30081 GO:0018645 biolink:MolecularActivity alkene monooxygenase activity Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O. MetaCyc:1.14.13.69-RXN|RHEA:11792|EC:1.14.13.69|UM-BBD_enzymeID:e0039 go-plus.json alkene,NADH:oxygen oxidoreductase activity|alkene epoxygenase activity http://purl.obolibrary.org/obo/GO_0018645 GO:0018644 biolink:MolecularActivity toluene 2-monooxygenase activity Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene. MetaCyc:TOLUENE-2-MONOOXYGENASE-RXN|UM-BBD_enzymeID:e0222|EC:1.14.13.243|RHEA:20349 go-plus.json http://purl.obolibrary.org/obo/GO_0018644 GO:0018647 biolink:MolecularActivity phenanthrene 1,2-monooxygenase activity Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide. UM-BBD_enzymeID:e0333|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0018647 GO:0018646 biolink:MolecularActivity 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate. UM-BBD_reactionID:r0736|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0018646 GO:0018641 biolink:MolecularActivity 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline. EC:1.14.13.-|UM-BBD_reactionID:r0048 go-plus.json http://purl.obolibrary.org/obo/GO_0018641 GO:0018640 biolink:MolecularActivity dibenzothiophene monooxygenase activity Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O. RHEA:49076|MetaCyc:RXN-621|UM-BBD_enzymeID:e0214 go-plus.json http://purl.obolibrary.org/obo/GO_0018640 GO:0018643 biolink:MolecularActivity carbon disulfide oxygenase activity Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide. EC:1.14.13.-|UM-BBD_reactionID:r0599 go-plus.json carbon disulphide oxygenase activity http://purl.obolibrary.org/obo/GO_0018643 GO:0018642 biolink:MolecularActivity chlorophenol 4-monooxygenase activity Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol. UM-BBD_enzymeID:e0252|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0018642 CHEBI:30089 biolink:ChemicalSubstance acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30089 chebi_ph7_3 NCBITaxon:7496 biolink:OrganismalEntity Pterygota go-plus.json winged insects|Pterygota http://purl.obolibrary.org/obo/NCBITaxon_7496 CHEBI:30088 biolink:ChemicalSubstance gibberellin A12 go-plus.json http://purl.obolibrary.org/obo/CHEBI_30088 CHEBI:30087 biolink:ChemicalSubstance guanidinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_30087 chebi_ph7_3 GO:0004019 biolink:MolecularActivity adenylosuccinate synthase activity Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate. KEGG_REACTION:R01135|EC:6.3.4.4|RHEA:15753|Reactome:R-HSA-111524|MetaCyc:ADENYLOSUCCINATE-SYNTHASE-RXN go-plus.json succinoadenylic kinosynthetase activity|IMP--aspartate ligase activity|succino-AMP synthetase activity|adenylosuccinate synthetase activity|IMP:L-aspartate ligase (GDP-forming) http://purl.obolibrary.org/obo/GO_0004019 GO:0004018 biolink:MolecularActivity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP. RHEA:16853|EC:4.3.2.2|KEGG_REACTION:R01083|Reactome:R-HSA-73800|Reactome:R-HSA-73828|MetaCyc:AMPSYN-RXN go-plus.json succino AMP-lyase activity|6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity|adenylosuccinate lyase activity|N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity|adenylosuccinase activity http://purl.obolibrary.org/obo/GO_0004018 GO:0004015 biolink:MolecularActivity adenosylmethionine-8-amino-7-oxononanoate transaminase activity Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate. EC:2.6.1.62|KEGG_REACTION:R03231|RHEA:16861|MetaCyc:DAPASYN-RXN go-plus.json 7,8-diaminonanoate transaminase activity|7-keto-8-aminopelargonic acid aminotransferase activity|7,8-diaminononanoate transaminase activity|DAPA transaminase activity|7-keto-8-aminopelargonic acid|adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity|S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity|7,8-diaminopelargonic acid aminotransferase activity|adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity|7,8-diaminononanoate aminotransferase activity|diaminopelargonate synthase activity|DAPA aminotransferase activity|adenosyl methionine-8-amino-7-oxononanoate transaminase activity|7,8-diamino-pelargonic acid aminotransferase activity http://purl.obolibrary.org/obo/GO_0004015 GO:0004014 biolink:MolecularActivity adenosylmethionine decarboxylase activity Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2). KEGG_REACTION:R00178|EC:4.1.1.50|RHEA:15981|MetaCyc:SAMDECARB-RXN|Reactome:R-HSA-351222 go-plus.json S-adenosylmethionine decarboxylase activity|adenosyl methionine decarboxylase activity|S-adenosyl-L-methionine carboxy-lyase activity|S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]|S-adenosyl-L-methionine decarboxylase activity http://purl.obolibrary.org/obo/GO_0004014 GO:0004017 biolink:MolecularActivity adenylate kinase activity Catalysis of the reaction: ATP + AMP = 2 ADP. RHEA:12973|EC:2.7.4.3|Reactome:R-HSA-110141|Reactome:R-HSA-74220|Reactome:R-HSA-110145|Reactome:R-HSA-110144|MetaCyc:ADENYL-KIN-RXN go-plus.json ATP:AMP phosphotransferase activity|5'-AMP-kinase activity|adenylic kinase activity|adenylokinase activity|myokinase activity http://purl.obolibrary.org/obo/GO_0004017 GO:0004016 biolink:MolecularActivity adenylate cyclase activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. Reactome:R-HSA-392129|Reactome:R-HSA-170676|RHEA:15389|Reactome:R-HSA-5211224|MetaCyc:ADENYLATECYC-RXN|EC:4.6.1.1|Reactome:R-HSA-381607|Reactome:R-HSA-164377|Reactome:R-HSA-5610727 go-plus.json 3',5'-cyclic AMP synthetase activity|adenylyl cyclase activity|ATP diphosphate-lyase (cyclizing) activity|ATP pyrophosphate-lyase activity|cAMP generating peptide activity|adenyl cyclase activity|adenylylcyclase activity|ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity http://purl.obolibrary.org/obo/GO_0004016 GO:0004011 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004011 GO:0004010 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004010 GO:0004013 biolink:MolecularActivity adenosylhomocysteinase activity Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine. Reactome:R-HSA-5579084|EC:3.3.1.1|MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN|Reactome:R-HSA-174401|RHEA:21708 go-plus.json adenosylhomocysteine hydrolase activity|S-adenosylhomocysteine hydrolase activity|SAHase activity|S-adenosylhomocysteine synthase activity|AdoHcyase activity|S-adenosyl-L-homocysteine hydrolase activity|S-adenosylhomocysteinase activity http://purl.obolibrary.org/obo/GO_0004013 goslim_chembl GO:0004012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004012 CHEBI:30095 biolink:ChemicalSubstance hydrazinide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30095 GO:0018659 biolink:MolecularActivity 4-hydroxybenzoate 3-monooxygenase activity Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O. MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN|EC:1.14.13.2|UM-BBD_reactionID:r0109 go-plus.json p-hydroxybenzoate hydroxylase activity|p-hydroxybenzoic acid hydrolase activity|4-hydroxybenzoate 3-hydroxylase activity|p-hydroxybenzoate hydrolyase activity|para-hydroxybenzoate hydroxylase activity|p-hydroxybenzoic acid hydroxylase activity|p-hydroxybenzoate-3-hydroxylase activity|4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)|4-hydroxybenzoate monooxygenase activity|p-hydroxybenzoic hydroxylase activity http://purl.obolibrary.org/obo/GO_0018659 CHEBI:30094 biolink:ChemicalSubstance diazenium go-plus.json http://purl.obolibrary.org/obo/CHEBI_30094 GO:0018656 biolink:MolecularActivity phenanthrene 3,4-monooxygenase activity Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide. UM-BBD_reactionID:r0508|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0018656 GO:0018655 biolink:MolecularActivity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA. EC:1.14.13.-|UM-BBD_reactionID:r0430 go-plus.json http://purl.obolibrary.org/obo/GO_0018655 GO:0018658 biolink:MolecularActivity salicylate 1-monooxygenase activity Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2. UM-BBD_enzymeID:e0149|MetaCyc:SALICYLATE-1-MONOOXYGENASE-RXN|EC:1.14.13.1|RHEA:11004 go-plus.json salicylate hydroxylase activity|salicylate monooxygenase activity|salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)|salicylic hydroxylase activity|salicylate hydroxylase (decarboxylating)|salicylate 1-hydroxylase activity http://purl.obolibrary.org/obo/GO_0018658 GO:0018657 biolink:MolecularActivity toluene 3-monooxygenase activity Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene. UM-BBD_enzymeID:e0224|EC:1.14.13.-|MetaCyc:TOLUENE-3-MONOOXYGENASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0018657 GO:0018652 biolink:MolecularActivity toluene-sulfonate methyl-monooxygenase activity Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol. MetaCyc:TSMOS-RXN|RHEA:51024|UM-BBD_reactionID:r0290 go-plus.json toluene-sulphonate methyl-monooxygenase activity http://purl.obolibrary.org/obo/GO_0018652 GO:0018651 biolink:MolecularActivity toluene-4-sulfonate monooxygenase activity Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene. EC:1.14.13.-|UM-BBD_reactionID:r0296 go-plus.json toluene-4-sulphonate monooxygenase activity http://purl.obolibrary.org/obo/GO_0018651 GO:0018654 biolink:MolecularActivity 2-hydroxy-phenylacetate hydroxylase activity Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate. EC:1.14.13.-|UM-BBD_reactionID:r0252 go-plus.json http://purl.obolibrary.org/obo/GO_0018654 GO:0018653 biolink:MolecularActivity 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline. EC:1.14.13.-|UM-BBD_reactionID:r0046 go-plus.json http://purl.obolibrary.org/obo/GO_0018653 CHEBI:30099 biolink:ChemicalSubstance diazynediium go-plus.json http://purl.obolibrary.org/obo/CHEBI_30099 GO:0018650 biolink:MolecularActivity styrene monooxygenase activity Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide. EC:1.14.13.-|UM-BBD_reactionID:r0225 go-plus.json http://purl.obolibrary.org/obo/GO_0018650 CHEBI:30096 biolink:ChemicalSubstance diazene go-plus.json http://purl.obolibrary.org/obo/CHEBI_30096 chebi_ph7_3 CHEBI:29076 biolink:ChemicalSubstance 3''-adenylylstreptomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29076 GO:0018627 biolink:MolecularActivity 2-aminobenzenesulfonate 2,3-dioxygenase activity Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol. RHEA:23468|MetaCyc:2ASDOSALCAL-RXN|KEGG_REACTION:R05156|EC:1.14.12.14|UM-BBD_reactionID:r0218 go-plus.json 2-aminobenzenesulfonate dioxygenase activity|2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)|2-aminosulfobenzene 2,3-dioxygenase activity|2-aminobenzenesulphonate dioxygenase activity|2-aminobenzenesulphonate 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018627 CHEBI:29084 biolink:ChemicalSubstance (2->1)-beta-D-fructan go-plus.json http://purl.obolibrary.org/obo/CHEBI_29084 chebi_ph7_3 GO:0018626 biolink:MolecularActivity 2-chlorobenzoate 1,2-dioxygenase activity Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2. UM-BBD_reactionID:r0632|RHEA:21652|MetaCyc:2-CHLOROBENZOATE-12-DIOXYGENASE-RXN|EC:1.14.12.13 go-plus.json 2-halobenzoate 1,2-dioxygenase activity|2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating) http://purl.obolibrary.org/obo/GO_0018626 CHEBI:29083 biolink:ChemicalSubstance N-methyl-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29083 chebi_ph7_3 GO:0018629 biolink:MolecularActivity 2-hydroxyquinoline 5,6-dioxygenase activity Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+. MetaCyc:1.14.12.16-RXN|RHEA:10976|UM-BBD_reactionID:r0052|EC:1.14.12.16 go-plus.json quinolin-2(1H)-one 5,6-dioxygenase activity|2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity|quinolin-2-ol 5,6-dioxygenase activity|quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating) http://purl.obolibrary.org/obo/GO_0018629 CHEBI:29086 biolink:ChemicalSubstance 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29086 GO:0018628 biolink:MolecularActivity terephthalate 1,2-dioxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+). MetaCyc:1.14.12.15-RXN|RHEA:10312|KEGG_REACTION:R05148|UM-BBD_reactionID:r0150|EC:1.14.12.15 go-plus.json benzene-1,4-dicarboxylate 1,2-dioxygenase activity|benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|1,4-dicarboxybenzoate 1,2-dioxygenase activity http://purl.obolibrary.org/obo/GO_0018628 GO:0018623 biolink:MolecularActivity benzoate 1,2-dioxygenase activity Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+. RHEA:12633|MetaCyc:BENZOATE-12-DIOXYGENASE-RXN|EC:1.14.12.10|UM-BBD_enzymeID:e0154 go-plus.json benzoic hydroxylase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzoate dioxygenase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)|benzoate hydroxylase activity http://purl.obolibrary.org/obo/GO_0018623 GO:0018622 biolink:MolecularActivity 4-chlorophenylacetate 3,4-dioxygenase activity Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+). KEGG_REACTION:R03306|RHEA:14689|MetaCyc:1.14.12.9-RXN|EC:1.14.12.9|UM-BBD_reactionID:r0308 go-plus.json 4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating) http://purl.obolibrary.org/obo/GO_0018622 GO:0018625 biolink:MolecularActivity naphthalene 1,2-dioxygenase activity Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+. MetaCyc:NAPHTHALENE-12-DIOXYGENASE-RXN|RHEA:19173|EC:1.14.12.12|UM-BBD_enzymeID:e0002 go-plus.json naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|naphthalene dioxygenase activity|naphthalene oxygenase activity http://purl.obolibrary.org/obo/GO_0018625 GO:0018624 biolink:MolecularActivity toluene dioxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+). KEGG_REACTION:R03559|RHEA:16737|MetaCyc:TOLUENE-DIOXYGENASE-RXN|EC:1.14.12.11|UM-BBD_enzymeID:e0155 go-plus.json toluene 1,2-dioxygenase activity|toluene 2,3-dioxygenase activity|toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating) http://purl.obolibrary.org/obo/GO_0018624 CHEBI:29081 biolink:ChemicalSubstance synephrine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29081 GO:0018621 biolink:MolecularActivity 4-sulfobenzoate 3,4-dioxygenase activity Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite. MetaCyc:4-SULFOBENZOATE-34-DIOXYGENASE-RXN|UM-BBD_reactionID:r0293|EC:1.14.12.8|RHEA:13937|KEGG_REACTION:R01636 go-plus.json 4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)|4-sulfobenzoate dioxygenase activity|4-sulphobenzoate 3,4-dioxygenase activity|4-sulfobenzoate 3,4-dioxygenase system http://purl.obolibrary.org/obo/GO_0018621 GO:0018620 biolink:MolecularActivity phthalate 4,5-dioxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+). UM-BBD_reactionID:r0102|KEGG_REACTION:R03630|RHEA:17489|MetaCyc:PHTHALATE-45-DIOXYGENASE-RXN|EC:1.14.12.7 go-plus.json phthalate dioxygenase activity|PDO activity|phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating) http://purl.obolibrary.org/obo/GO_0018620 CHEBI:30066 biolink:ChemicalSubstance thioglycolate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30066 chebi_ph7_3 CHEBI:30065 biolink:ChemicalSubstance thioglycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30065 NCBITaxon:41088 biolink:OrganismalEntity Cucujiformia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_41088 NCBITaxon:41087 biolink:OrganismalEntity Elateriformia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_41087 CHEBI:29089 biolink:ChemicalSubstance 1,2-diacyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29089 GO:0018638 biolink:MolecularActivity toluene 4-monooxygenase activity Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene. UM-BBD_enzymeID:e0225|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0018638 GO:0018637 biolink:MolecularActivity 1-hydroxy-2-naphthoate hydroxylase activity Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene. EC:1.14.13.-|UM-BBD_reactionID:r0491 go-plus.json http://purl.obolibrary.org/obo/GO_0018637 CHEBI:29094 biolink:ChemicalSubstance homoisocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29094 GO:0018639 biolink:MolecularActivity xylene monooxygenase activity Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol. EC:1.14.13.-|UM-BBD_enzymeID:e0172 go-plus.json http://purl.obolibrary.org/obo/GO_0018639 GO:0018634 biolink:MolecularActivity alpha-pinene monooxygenase [NADH] activity Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide. EC:1.14.13.-|UM-BBD_reactionID:r0742 go-plus.json http://purl.obolibrary.org/obo/GO_0018634 CHEBI:29091 biolink:ChemicalSubstance nocardicin E go-plus.json http://purl.obolibrary.org/obo/CHEBI_29091 GO:0018633 biolink:MolecularActivity dimethyl sulfide monooxygenase activity Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde. UM-BBD_reactionID:r0208|EC:1.14.13.- go-plus.json dimethyl sulphide monooxygenase activity http://purl.obolibrary.org/obo/GO_0018633 NCBITaxon:41084 biolink:OrganismalEntity Polyphaga go-plus.json Polyphaga http://purl.obolibrary.org/obo/NCBITaxon_41084 CHEBI:29090 biolink:ChemicalSubstance D-2-aminohexano-6-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_29090 GO:0018636 biolink:MolecularActivity phenanthrene 9,10-monooxygenase activity Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide. EC:1.14.13.-|UM-BBD_reactionID:r0495 go-plus.json http://purl.obolibrary.org/obo/GO_0018636 GO:0018635 biolink:MolecularActivity (R)-limonene 1,2-monooxygenase activity Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide. EC:1.14.13.107|MetaCyc:RXN-9407|UM-BBD_reactionID:r0733|KEGG_REACTION:R09393|KEGG_REACTION:R06398 go-plus.json (+)-limonene 1,2-monooxygenase activity|(+)-limonene,NAD(P)H:oxygen oxidoreductase activity|(R)-limonene,NAD(P)H:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0018635 GO:0018630 biolink:MolecularActivity 3,5-xylenol methylhydroxylase activity Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol. MetaCyc:3-5-XYLENOL-METHYLHYDROXYLASE-RXN|EC:1.14.13.-|UM-BBD_reactionID:r0081 go-plus.json http://purl.obolibrary.org/obo/GO_0018630 GO:0018632 biolink:MolecularActivity 4-nitrophenol 4-monooxygenase activity Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone. MetaCyc:RXN-8739|EC:1.14.13.167|UM-BBD_reactionID:r0226|RHEA:34327 go-plus.json http://purl.obolibrary.org/obo/GO_0018632 GO:0018631 biolink:MolecularActivity phenylacetate hydroxylase activity Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate. EC:1.14.13.-|UM-BBD_reactionID:r0036 go-plus.json http://purl.obolibrary.org/obo/GO_0018631 CHEBI:30049 biolink:ChemicalSubstance teichoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30049 GO:0018609 biolink:MolecularActivity chlorobenzene dioxygenase activity Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene). EC:1.14.12.-|UM-BBD_enzymeID:e0062 go-plus.json http://purl.obolibrary.org/obo/GO_0018609 CHEBI:29055 biolink:ChemicalSubstance 3,4-dihydroxyphenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29055 chebi_ph7_3 GO:0018608 biolink:MolecularActivity 1-indanone dioxygenase activity Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone. UM-BBD_reactionID:r0416|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0018608 CHEBI:29057 biolink:ChemicalSubstance keratan go-plus.json http://purl.obolibrary.org/obo/CHEBI_29057 CHEBI:29056 biolink:ChemicalSubstance lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_29056 GO:0018605 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018605 CHEBI:29062 biolink:ChemicalSubstance GDP-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_29062 GO:0018604 biolink:MolecularActivity 4-aminobenzoate 3,4-dioxygenase (deaminating) activity Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate. EC:1.14.12.-|UM-BBD_reactionID:r0566 go-plus.json http://purl.obolibrary.org/obo/GO_0018604 GO:0018607 biolink:MolecularActivity 1-indanone monooxygenase activity Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin. UM-BBD_reactionID:r0417|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0018607 CHEBI:29064 biolink:ChemicalSubstance 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_29064 chebi_ph7_3 GO:0018606 biolink:MolecularActivity benzenesulfonate dioxygenase activity Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol. EC:1.14.12.-|UM-BBD_reactionID:r0295 go-plus.json benzenesulphonate dioxygenase activity http://purl.obolibrary.org/obo/GO_0018606 CHEBI:29063 biolink:ChemicalSubstance L-mimosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29063 GO:0018601 biolink:MolecularActivity 4-nitrophenol 2-monooxygenase activity Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+). RHEA:12568|MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0230|KEGG_REACTION:R03023|EC:1.14.13.29 go-plus.json 4-nitrophenol-2-hydroxylase activity|4-nitrophenol hydroxylase activity|4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating) http://purl.obolibrary.org/obo/GO_0018601 GO:0018600 biolink:MolecularActivity alpha-pinene dehydrogenase activity Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol. UM-BBD_reactionID:r0709|EC:1.14.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0018600 GO:0018603 biolink:MolecularActivity nitrobenzene 1,2-dioxygenase activity Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol. UM-BBD_reactionID:r0306|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0018603 CHEBI:29060 biolink:ChemicalSubstance alpha-pinene oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29060 chebi_ph7_3 GO:0018602 biolink:MolecularActivity 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2. MetaCyc:RXN-9863|UM-BBD_reactionID:r0274|RHEA:48984 go-plus.json http://purl.obolibrary.org/obo/GO_0018602 UBERON:0005434 biolink:AnatomicalEntity cervical region go-plus.json subdivision of neck|neck subdivision|cervical region|region of neck http://purl.obolibrary.org/obo/UBERON_0005434 CHEBI:30043 biolink:ChemicalSubstance terephthalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30043 chebi_ph7_3 CHEBI:30042 biolink:ChemicalSubstance taxa-4(20),11-dien-5alpha-yl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30042 chebi_ph7_3 UBERON:0005432 biolink:AnatomicalEntity aortic sac The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates go-plus.json saccus aorticus http://purl.obolibrary.org/obo/UBERON_0005432 CHEBI:30041 biolink:ChemicalSubstance taxa-4(20),11-dien-5alpha,13alpha-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_30041 chebi_ph7_3 CHEBI:44680 biolink:ChemicalSubstance 3-oxooctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44680 UBERON:0005419 biolink:AnatomicalEntity pectoral appendage bud A limb bud that develops into a forelimb or pectoral fin. go-plus.json pectoral fin buds|forelimb - pectoral fin bud|pectoral fin bud http://purl.obolibrary.org/obo/UBERON_0005419 UBERON:0005418 biolink:AnatomicalEntity hindlimb bud A limb bud that develops into a hindlimb. go-plus.json leg bud|limb bud - hindlimb|hind limb bud|posterior limb bud http://purl.obolibrary.org/obo/UBERON_0005418 CHEBI:29069 biolink:ChemicalSubstance phthalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29069 GO:0018619 biolink:MolecularActivity benzene 1,2-dioxygenase activity Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+). EC:1.14.12.3|RHEA:13813|MetaCyc:BENZENE-12-DIOXYGENASE-RXN|UM-BBD_reactionID:r0079|KEGG_REACTION:R03543 go-plus.json benzene hydroxylase activity|benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzene dioxygenase activity http://purl.obolibrary.org/obo/GO_0018619 CHEBI:29065 biolink:ChemicalSubstance N-acetyl-O-acetylneuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29065 CHEBI:29067 biolink:ChemicalSubstance carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_29067 chebi_ph7_3 GO:0018616 biolink:MolecularActivity trihydroxytoluene dioxygenase activity Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate. MetaCyc:R305-RXN|UM-BBD_reactionID:r0093 go-plus.json http://purl.obolibrary.org/obo/GO_0018616 CHEBI:29073 biolink:ChemicalSubstance L-ascorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29073 UBERON:0005420 biolink:AnatomicalEntity pelvic appendage bud A limb bud that develops into a hindlimb or pelvic fin. go-plus.json hindlimb/pelvic fin bud|pelvic fin buds|pelvic fin bud http://purl.obolibrary.org/obo/UBERON_0005420 GO:0018615 biolink:MolecularActivity 2-indanone monooxygenase activity Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone. UM-BBD_reactionID:r0424|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0018615 GO:0018618 biolink:MolecularActivity anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3. MetaCyc:1.14.12.1-RXN|EC:1.14.12.1|UM-BBD_reactionID:r0577 go-plus.json anthranilic acid hydroxylase activity|anthranilate 1,2-dioxygenase|anthranilate dioxygenase reductase|anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)|AntC|anthranilate hydroxylase activity|AntB|AntA|anthranilate dioxygenase activity|anthranilic hydroxylase activity http://purl.obolibrary.org/obo/GO_0018618 CHEBI:29075 biolink:ChemicalSubstance mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29075 GO:0018617 biolink:MolecularActivity 4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol. EC:1.14.12.-|UM-BBD_reactionID:r0580 go-plus.json 4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity http://purl.obolibrary.org/obo/GO_0018617 CHEBI:29074 biolink:ChemicalSubstance dolichyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29074 chebi_ph7_3 GO:0018612 biolink:MolecularActivity dibenzothiophene dioxygenase activity Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene. EC:1.14.12.-|UM-BBD_reactionID:r0160 go-plus.json http://purl.obolibrary.org/obo/GO_0018612 GO:0018611 biolink:MolecularActivity toluate dioxygenase activity Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate. EC:1.14.12.-|UM-BBD_enzymeID:e0190 go-plus.json http://purl.obolibrary.org/obo/GO_0018611 GO:0018614 biolink:MolecularActivity ethylbenzene dioxygenase activity Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene. EC:1.14.12.-|UM-BBD_reactionID:r0247 go-plus.json http://purl.obolibrary.org/obo/GO_0018614 CHEBI:29071 biolink:ChemicalSubstance 3-deoxy-D-glycero-hexo-2,5-diulosonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29071 chebi_ph7_3 GO:0018613 biolink:MolecularActivity 9-fluorenone dioxygenase activity Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone. UM-BBD_reactionID:r0409|EC:1.14.12.- go-plus.json http://purl.obolibrary.org/obo/GO_0018613 UBERON:0005428 biolink:AnatomicalEntity vagal neural crest Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]. go-plus.json VNC|post-otic neural crest|enteric neural crest http://purl.obolibrary.org/obo/UBERON_0005428 UBERON:0005427 biolink:AnatomicalEntity corneal primordium Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005427 UBERON:0005426 biolink:AnatomicalEntity lens vesicle Portion of tissue that gives rise to the lens. go-plus.json immature lens|presumptive lens|hollow lens vesicle|lens mass|solid lens vesicle http://purl.obolibrary.org/obo/UBERON_0005426 GO:0018610 biolink:MolecularActivity dibenzofuran 4,4a-dioxygenase activity Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+. MetaCyc:R606-RXN|UM-BBD_enzymeID:e0030|RHEA:42460 go-plus.json http://purl.obolibrary.org/obo/GO_0018610 UBERON:0005425 biolink:AnatomicalEntity presumptive neural retina Portion of tissue that is the inner layer of the optic cup and will become the neural retina. go-plus.json presumptive retina|future neural layer|future neural epithelium|presumptive retinas|future neural retina|future NR|future retinal neural layer|inner layer optic cup|optic cup inner layer http://purl.obolibrary.org/obo/UBERON_0005425 UBERON:0005424 biolink:AnatomicalEntity presumptive retinal pigmented epithelium Portion of tissue that is the outer layer of the optic cup and will become the retinal pigmented epithelium. go-plus.json presumptive pigmented epithelium|future RPE|future retinal pigmented epithelium|presumptive pigmented epithelia|future pigmented retinal epithelium|future PRE|future pigmented layer|optic cup outer layer|outer layer optic cup http://purl.obolibrary.org/obo/UBERON_0005424 UBERON:0005423 biolink:AnatomicalEntity developing anatomical structure go-plus.json developmental tissue|developmental structure|developing structure http://purl.obolibrary.org/obo/UBERON_0005423 UBERON:0005422 biolink:AnatomicalEntity pelvic appendage apical ectodermal ridge An apical ectodermal ridge that is part of a pelvic appendage bud. go-plus.json apical ectodermal ridge pelvic fin bud|apical ectodermal ridge hind limb|leg AER|apical ectodermal ridge hindlimb|AER hindlimb|lower lmb bud apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0005422 UBERON:0005421 biolink:AnatomicalEntity pectoral appendage apical ectodermal ridge An apical ectodermal ridge that is part of a pectoral appendage bud. go-plus.json wing apical ectodermal ridge|AER forelimb|apical ectodermal ridge pectoral fin|wing AER|apical ectodermal ridge pectoral fin bud|upper limb bud apical ectodermal ridge|apical ectodermal ridge forelimb|apical fold pectoral fin|aer pectoral fin http://purl.obolibrary.org/obo/UBERON_0005421 UBERON:0005409 biolink:AnatomicalEntity alimentary part of gastrointestinal system The part of the digestive system that excludes the hepatobiliary system. go-plus.json GI tract|gastroenterological system|gastrointestinal (GI) tract|gastro-intestinal system|gastrointestinal tract|gastrointestinal system|alimentary system|alimentary tract http://purl.obolibrary.org/obo/UBERON_0005409 UBERON:0005408 biolink:AnatomicalEntity circumventricular organ Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. go-plus.json circumventricular organ|circumventricular organ of neuraxis|CVO http://purl.obolibrary.org/obo/UBERON_0005408 CHEBI:44678 biolink:ChemicalSubstance alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44678 CHEBI:29036 biolink:ChemicalSubstance copper(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29036 chebi_ph7_3 CHEBI:29039 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29039 CHEBI:29033 biolink:ChemicalSubstance iron(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29033 chebi_ph7_3 CHEBI:29032 biolink:ChemicalSubstance (R)-pantothenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29032 chebi_ph7_3 CHEBI:29035 biolink:ChemicalSubstance manganese(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29035 chebi_ph7_3 CHEBI:29034 biolink:ChemicalSubstance iron(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29034 chebi_ph7_3 CHEBI:29042 biolink:ChemicalSubstance alpha-D-glucose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29042 CHEBI:29041 biolink:ChemicalSubstance manganese(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29041 chebi_ph7_3 UBERON:0005417 biolink:AnatomicalEntity forelimb bud A limb bud that develops into a forelimb. go-plus.json limb bud - forelimb|anterior limb bud|arm bud|upper limb bud|wing bud http://purl.obolibrary.org/obo/UBERON_0005417 CHEBI:30023 biolink:ChemicalSubstance trans-sinapate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30023 chebi_ph7_3 CHEBI:30022 biolink:ChemicalSubstance D-selenomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30022 CHEBI:30021 biolink:ChemicalSubstance L-selenomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30021 UBERON:0005411 biolink:AnatomicalEntity bony otic capsule the cartilage or bony capsule surrounding the inner ear mechanism go-plus.json otic capsule bone http://purl.obolibrary.org/obo/UBERON_0005411 UBERON:0005410 biolink:AnatomicalEntity cartilaginous otic capsule A otic capsule endochondral element that is composed primarily of cartilage tissue. go-plus.json auditory capsule|otic capsule cartilage element http://purl.obolibrary.org/obo/UBERON_0005410 CHEBI:30038 biolink:ChemicalSubstance taxa-4(20),11-dien-5alpha-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_30038 chebi_ph7_3 CHEBI:68612 biolink:ChemicalSubstance EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_68612 CHEBI:44667 biolink:ChemicalSubstance L-ornithinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_44667 CHEBI:44666 biolink:ChemicalSubstance 2'-O-methylcytidine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44666 CHEBI:29044 biolink:ChemicalSubstance 2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29044 CHEBI:29043 biolink:ChemicalSubstance O-beta-D-glucosyl-cis-zeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29043 chebi_ph7_3 CHEBI:29045 biolink:ChemicalSubstance maleamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29045 CHEBI:29051 biolink:ChemicalSubstance D-mannosyl undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29051 CHEBI:29053 biolink:ChemicalSubstance pyridine-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29053 chebi_ph7_3 CHEBI:29052 biolink:ChemicalSubstance D-glyceraldehyde 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29052 CHEBI:30037 biolink:ChemicalSubstance taxa-4,11-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_30037 chebi_ph7_3 UBERON:0005404 biolink:AnatomicalEntity frontonasal suture A suture between frontal and nasal bones go-plus.json frontonasal suture of skull|articulation of the nasal bone with frontal bone http://purl.obolibrary.org/obo/UBERON_0005404 UBERON:0005403 biolink:AnatomicalEntity ventral striatum A composite structure of the telencephalon that is defined in the striatopallidal system by connectivity and neurochemical staining. It includes the nucleus accumbens, the most ventral portions of the caudate nucleus and the putamen, the rostrolateral portion of the anterior perforated substance, the islands of Calleja and a rostral subcommissural portion of substantia innominata. The boundary between the ventral striatum and dorsal striatum is indistinct in sections stained for Nissl substance (Heimer-1995; adapted from Brain Info). go-plus.json striatum ventral region|striatum ventrale http://purl.obolibrary.org/obo/UBERON_0005403 CHEBI:30033 biolink:ChemicalSubstance bacteriochlorophyll a go-plus.json http://purl.obolibrary.org/obo/CHEBI_30033 UBERON:0005401 biolink:AnatomicalEntity cerebral hemisphere gray matter A gray matter that is part of a cerebral hemisphere. go-plus.json cerebral gray matter|cerebral hemisphere grey matter|cerebral grey matter http://purl.obolibrary.org/obo/UBERON_0005401 UBERON:0005400 biolink:AnatomicalEntity telencephalon arachnoid mater An arachnoid mater that is part of a telencephalon. go-plus.json telencephalon arachnoid matter http://purl.obolibrary.org/obo/UBERON_0005400 CHEBI:30031 biolink:ChemicalSubstance succinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30031 chebi_ph7_3 GO:0102630 biolink:MolecularActivity gossypetin 8-methyl ester 3'-O-methyltransferase activity Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15536 go-plus.json http://purl.obolibrary.org/obo/GO_0102630 GO:0102632 biolink:MolecularActivity (S)-nandinine synthase activity Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-nandinine + [oxidized NADPH--hemoprotein reductase] + 2 H2O. EC:1.14.19.73|RHEA:50364|MetaCyc:RXN-15538 go-plus.json http://purl.obolibrary.org/obo/GO_0102632 GO:0102631 biolink:MolecularActivity caffeoylglucose 3-O-methyltransferase activity Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15537 go-plus.json http://purl.obolibrary.org/obo/GO_0102631 GO:0102634 biolink:MolecularActivity 1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+. MetaCyc:RXN-15586 go-plus.json http://purl.obolibrary.org/obo/GO_0102634 GO:0102633 biolink:MolecularActivity flaviolin monooxygenase activity Catalysis of the reaction: flaviolin-2-olate + NADH + H+ + O2 <=> mompain + NAD + H2O. MetaCyc:RXN-15585 go-plus.json http://purl.obolibrary.org/obo/GO_0102633 GO:0102636 biolink:MolecularActivity 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine gamma-glutamylcyclotransferase activity Catalysis of the reaction: 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine <=> 3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine + 2 5-oxo-L-prolinate. MetaCyc:RXN-15681 go-plus.json http://purl.obolibrary.org/obo/GO_0102636 GO:0102635 biolink:MolecularActivity 11-deoxycorticosterone reductase activity Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ <=> 4-pregnen-20,21-diol-3-one + NAD. RHEA:47716|MetaCyc:RXN-15607 go-plus.json http://purl.obolibrary.org/obo/GO_0102635 GO:0102638 biolink:MolecularActivity [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid. MetaCyc:RXN-15734|EC:2.5.1.105 go-plus.json http://purl.obolibrary.org/obo/GO_0102638 GO:0102637 biolink:MolecularActivity 5-aminolevulinate-CoA ligase activity Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid. MetaCyc:RXN-15714 go-plus.json http://purl.obolibrary.org/obo/GO_0102637 GO:0102639 biolink:MolecularActivity paspalicine synthase activity Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O. MetaCyc:RXN-15737 go-plus.json http://purl.obolibrary.org/obo/GO_0102639 GO:0102641 biolink:MolecularActivity (R)-lactaldehyde dehydrogenase activity Catalysis of the reaction: (R)-propane-1,2-diol + NADP <=> (R)-lactaldehyde + NADPH + H+. MetaCyc:RXN-15743 go-plus.json http://purl.obolibrary.org/obo/GO_0102641 GO:0102640 biolink:MolecularActivity paspalinine synthase activity Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O. MetaCyc:RXN-15738 go-plus.json http://purl.obolibrary.org/obo/GO_0102640 GO:0102643 biolink:MolecularActivity scalarane-17alpha-19-diol synthase activity Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O. MetaCyc:RXN-15755 go-plus.json http://purl.obolibrary.org/obo/GO_0102643 GO:0102645 biolink:MolecularActivity 17(E)-cheilanthenediol synthase activity Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O. MetaCyc:RXN-15758 go-plus.json http://purl.obolibrary.org/obo/GO_0102645 GO:0102644 biolink:MolecularActivity monocyclic sesterterpenediol synthase activity Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O. MetaCyc:RXN-15756 go-plus.json http://purl.obolibrary.org/obo/GO_0102644 GO:0102647 biolink:MolecularActivity D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate. MetaCyc:RXN-15789 go-plus.json http://purl.obolibrary.org/obo/GO_0102647 GO:0102646 biolink:MolecularActivity 14betaH-scalarane-17alpha-19-diol synthase activity Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O. MetaCyc:RXN-15759 go-plus.json http://purl.obolibrary.org/obo/GO_0102646 GO:0102649 biolink:MolecularActivity acetoacetyl-ACP synthase activity Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide. MetaCyc:RXN-15810 go-plus.json http://purl.obolibrary.org/obo/GO_0102649 GO:0102648 biolink:MolecularActivity D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity Catalysis of the reaction: D-fructose 6-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-glyceraldehyde 3-phosphate. MetaCyc:RXN-15790 go-plus.json http://purl.obolibrary.org/obo/GO_0102648 GO:0102650 biolink:MolecularActivity cyclo-acetoacetyl-L-tryptophan synthetase activity Catalysis of the reaction: acetoacetyl-ACP + L-tryptophan + ATP <=> cyclo-acetoacetyl-L-tryptophan + AMP + diphosphoric acid + 2 H+ + a holo-[acyl-carrier protein]. MetaCyc:RXN-15811 go-plus.json http://purl.obolibrary.org/obo/GO_0102650 GO:0004187 biolink:MolecularActivity obsolete carboxypeptidase D activity OBSOLETE. Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents. go-plus.json carboxypeptidase Kex1|KEX1 proteinase activity|saccharomyces cerevisiae KEX1 gene product|carboxypeptidase S1 activity|CPDW-II|KEX1DELTAp|gene KEX1 serine carboxypeptidase|KEX1 carboxypeptidase activity|carboxypeptidase KEX1 activity|cereal serine carboxypeptidase II|carboxypeptidase D activity http://purl.obolibrary.org/obo/GO_0004187 GO:0102652 biolink:MolecularActivity gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A9 + 2-oxoglutarate + O2 <=> gibberellin A51 + succinate + carbon dioxide. MetaCyc:RXN-171 go-plus.json http://purl.obolibrary.org/obo/GO_0102652 GO:0004186 biolink:MolecularActivity obsolete carboxypeptidase C activity OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity. go-plus.json lysosomal carboxypeptidase A|serine-type carboxypeptidase I activity|deamidase|serine carboxypeptidase I activity|lysosomal protective protein activity|vacuolar carboxypeptidase Y|carboxypeptidase C activity|cathepsin A activity|carboxypeptidase Y activity http://purl.obolibrary.org/obo/GO_0004186 GO:0102654 biolink:MolecularActivity 1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:1-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.43|RHEA:46764|MetaCyc:RXN-1725 go-plus.json http://purl.obolibrary.org/obo/GO_0102654 GO:0004189 biolink:MolecularActivity obsolete tubulinyl-Tyr carboxypeptidase activity OBSOLETE. Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr. go-plus.json tyrosinotubulin carboxypeptidase activity|tubulinyl-Tyr carboxypeptidase activity|tubulinyltyrosine carboxypeptidase activity|tubulin-tyrosine carboxypeptidase activity|brain I carboxypeptidase activity|tubulin carboxypeptidase activity|tubulinyl-tyrosine carboxypeptidase activity|tyrosyltubulin carboxypeptidase activity|TTCPase activity|soluble carboxypeptidase activity|carboxypeptidase-tubulin activity http://purl.obolibrary.org/obo/GO_0004189 GO:0004188 biolink:MolecularActivity obsolete serine-type Pro-X carboxypeptidase activity OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid. go-plus.json proline carboxypeptidase activity|lysosomal Pro-X carboxypeptidase activity|proline-specific carboxypeptidase P|lysosomal carboxypeptidase C activity|peptidylprolylamino acid carboxypeptidase activity|prolyl carboxypeptidase activity|aminoacylproline carboxypeptidase activity|serine-type Pro-X carboxypeptidase activity|angiotensinase C activity|lysosomal Pro-Xaa carboxypeptidase activity|PCP http://purl.obolibrary.org/obo/GO_0004188 GO:0102653 biolink:MolecularActivity gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A51 + 2-oxoglutarate + O2 <=> H+ + gibberellin A51-catabolite + succinate + carbon dioxide + H2O. MetaCyc:RXN-172 go-plus.json http://purl.obolibrary.org/obo/GO_0102653 GO:0004183 biolink:MolecularActivity obsolete carboxypeptidase E activity OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents. go-plus.json peptidyl-L-lysine(-L-arginine) hydrolase|enkephalin-precursor endopeptidase activity|enkephalin convertase activity|insulin granule-associated carboxypeptidase activity|cobalt-stimulated chromaffin granule carboxypeptidase activity|carboxypeptidase E activity|membrane-bound carboxypeptidase activity|enkephalin precursor carboxypeptidase activity|carboxypeptidase H activity http://purl.obolibrary.org/obo/GO_0004183 GO:0102656 biolink:MolecularActivity 1-18:2-2-trans-16:1-phosphatidylglycerol desaturase activity Catalysis of the reaction: 1-18:2-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. MetaCyc:RXN-1727 go-plus.json http://purl.obolibrary.org/obo/GO_0102656 GO:0102655 biolink:MolecularActivity 1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.23|MetaCyc:RXN-1726 go-plus.json http://purl.obolibrary.org/obo/GO_0102655 GO:0004182 biolink:MolecularActivity obsolete carboxypeptidase A activity OBSOLETE. Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. go-plus.json carboxypeptidase A activity|carboxypolypeptidase activity|tissue carboxypeptidase A|pancreatic carboxypeptidase A http://purl.obolibrary.org/obo/GO_0004182 GO:0102658 biolink:MolecularActivity 2-oxo-5-methylthiopentanoate aminotransferase activity Catalysis of the reaction: 5-methylthio-2-oxopentanoate + a standard alpha amino acid <=> L-homomethionine + a 2-oxo carboxylate. MetaCyc:RXN-2205 go-plus.json http://purl.obolibrary.org/obo/GO_0102658 GO:0004185 biolink:MolecularActivity serine-type carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). EC:3.4.16.6|EC:3.4.16.5|EC:3.4.16.2|Reactome:R-HSA-158251|EC:3.4.16.-|MetaCyc:3.4.16.6-RXN|MetaCyc:3.4.16.5-RXN|MetaCyc:3.4.16.2-RXN go-plus.json serine carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0004185 GO:0004184 biolink:MolecularActivity obsolete lysine carboxypeptidase activity OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma. go-plus.json CPase N|carboxypeptidase N activity|bradykinin-decomposing enzyme|peptidyl-L-lysine(-L-arginine) hydrolase|hippuryllysine hydrolase activity|anaphylatoxin inactivator activity|lysine(arginine) carboxypeptidase activity|kininase I activity|bradykinase activity|creatine kinase conversion factor|lysine (arginine) carboxypeptidase activity|creatinine kinase convertase activity|plasma carboxypeptidase B|lysine carboxypeptidase activity|kininase Ia|arginine carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0004184 GO:0102657 biolink:MolecularActivity 1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. EC:1.14.19.42|MetaCyc:RXN-1728 go-plus.json http://purl.obolibrary.org/obo/GO_0102657 GO:0004190 biolink:MolecularActivity aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. EC:3.4.23.-|MetaCyc:3.4.23.5-RXN|MetaCyc:3.4.23.4-RXN|Reactome:R-HSA-2022403|MetaCyc:3.4.23.1-RXN|MetaCyc:3.4.23.15-RXN|MetaCyc:3.4.23.25-RXN|MetaCyc:3.4.23.36-RXN|MetaCyc:3.4.23.35-RXN|MetaCyc:3.4.23.34-RXN|Reactome:R-HSA-9013361|MetaCyc:3.4.23.43-RXN|EC:3.4.23.15|MetaCyc:3.4.23.32-RXN|MetaCyc:3.4.23.20-RXN|EC:3.4.23.25|EC:3.4.23.36|EC:3.4.23.35|EC:3.4.23.34|EC:3.4.23.43|EC:3.4.23.32|Reactome:R-HSA-2065357|EC:3.4.23.20|EC:3.4.23.5|EC:3.4.23.4|Reactome:R-HSA-2022412|Reactome:R-HSA-9017817|Reactome:R-HSA-157353|EC:3.4.23.1|Reactome:R-HSA-157640|Reactome:R-HSA-373705|Reactome:R-HSA-2220988|Reactome:R-HSA-9604294 go-plus.json carboxyl protease activity|aspartic endopeptidase activity|aspartic protease activity|aspartate protease activity|aspartyl protease activity http://purl.obolibrary.org/obo/GO_0004190 GO:0102659 biolink:MolecularActivity UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP. MetaCyc:RXN-2208|EC:2.4.1.195 go-plus.json http://purl.obolibrary.org/obo/GO_0102659 CHEBI:6877 biolink:ChemicalSubstance trans-isomethyleugenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_6877 chebi_ph7_3 GO:0004192 biolink:MolecularActivity obsolete cathepsin D activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin. go-plus.json cathepsin D activity http://purl.obolibrary.org/obo/GO_0004192 GO:0004191 biolink:MolecularActivity obsolete barrierpepsin activity OBSOLETE. Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor. go-plus.json Bar proteinase activity|extracellular 'barrier' protein activity|barrier proteinase activity|barrierpepsin activity http://purl.obolibrary.org/obo/GO_0004191 GO:0102661 biolink:MolecularActivity homogentisate solanyltransferase activity Catalysis of the reaction: all-trans-nonaprenyl diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone + carbon dioxide + diphosphoric acid. MetaCyc:RXN-2761|RHEA:37995|EC:2.5.1.117 go-plus.json http://purl.obolibrary.org/obo/GO_0102661 GO:0102660 biolink:MolecularActivity caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate. MetaCyc:RXN-2621 go-plus.json http://purl.obolibrary.org/obo/GO_0102660 GO:0102663 biolink:MolecularActivity gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: gibberellin A34 + 2-oxoglutarate + O2 <=> H+ + gibberellin A34-catabolite + succinate + carbon dioxide + H2O. MetaCyc:RXN-292 go-plus.json http://purl.obolibrary.org/obo/GO_0102663 GO:0004198 biolink:MolecularActivity calcium-dependent cysteine-type endopeptidase activity Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium. Reactome:R-HSA-8863012|Reactome:R-HSA-8848658 go-plus.json calpain activity http://purl.obolibrary.org/obo/GO_0004198 GO:0004197 biolink:MolecularActivity cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. Reactome:R-HSA-933532|Reactome:R-HSA-2130504|Reactome:R-HSA-2028692|Reactome:R-HSA-351876|Reactome:R-HSA-201595|Reactome:R-HSA-9647999|Reactome:R-HSA-418852|Reactome:R-HSA-351913|Reactome:R-HSA-211651|Reactome:R-HSA-202969|EC:3.4.22.-|Reactome:R-HSA-9012556|Reactome:R-HSA-1678920|Reactome:R-HSA-418845|Reactome:R-HSA-201634|Reactome:R-HSA-5634228|Reactome:R-HSA-2562564|Reactome:R-HSA-211190|Reactome:R-HSA-201639|Reactome:R-HSA-264871|Reactome:R-HSA-448703|Reactome:R-HSA-5357828|Reactome:R-HSA-202939|Reactome:R-HSA-264865|Reactome:R-HSA-202960|Reactome:R-HSA-114252|Reactome:R-HSA-9694551|MetaCyc:3.4.22.16-RXN|MetaCyc:3.4.22.27-RXN|MetaCyc:3.4.22.38-RXN|Reactome:R-HSA-1236948|Reactome:R-HSA-201636|MetaCyc:3.4.22.15-RXN|MetaCyc:3.4.22.14-RXN|MetaCyc:3.4.22.1-RXN|Reactome:R-HSA-9603534|Reactome:R-HSA-9686930|Reactome:R-HSA-5682377|Reactome:R-HSA-9697750|Reactome:R-HSA-201628|Reactome:R-HSA-2130336|Reactome:R-HSA-201637|EC:3.4.22.28|MetaCyc:3.4.22.34-RXN|EC:3.4.22.16|Reactome:R-HSA-114261|Reactome:R-HSA-202917|EC:3.4.22.27|EC:3.4.22.38|Reactome:R-HSA-9693929|EC:3.4.22.15|Reactome:R-HSA-351894|Reactome:R-HSA-351871|Reactome:R-HSA-201629|Reactome:R-HSA-202947|EC:3.4.22.14|Reactome:R-HSA-2130706|Reactome:R-HSA-9694441|Reactome:R-HSA-201640|MetaCyc:3.4.22.41-RXN|Reactome:R-HSA-211186|Reactome:R-HSA-9694625|Reactome:R-HSA-351877|Reactome:R-HSA-351901|Reactome:R-HSA-201603|MetaCyc:3.4.22.40-RXN|EC:3.4.22.34|Reactome:R-HSA-1678981|Reactome:R-HSA-9694732|Reactome:R-HSA-139952|Reactome:R-HSA-9684273|EC:3.4.22.8|Reactome:R-HSA-5681987|Reactome:R-HSA-9694601|Reactome:R-HSA-350318|EC:3.4.22.41|Reactome:R-HSA-9694338|EC:3.4.22.40|Reactome:R-HSA-3465448|Reactome:R-HSA-202967|Reactome:R-HSA-201608|Reactome:R-HSA-9684321|Reactome:R-HSA-9694377|Reactome:R-HSA-350158|Reactome:R-HSA-9684336|Reactome:R-HSA-201631|Reactome:R-HSA-139898|Reactome:R-HSA-2130349|Reactome:R-HSA-2028697|Reactome:R-HSA-9684340|Reactome:R-HSA-6814387|Reactome:R-HSA-201622|Reactome:R-HSA-418846|EC:3.4.22.1|Reactome:R-HSA-201630|Reactome:R-HSA-202966|Reactome:R-HSA-201611|Reactome:R-HSA-352268|Reactome:R-HSA-9684351|Reactome:R-HSA-350319|Reactome:R-HSA-351936|Reactome:R-HSA-9684309|Reactome:R-HSA-9684352|Reactome:R-HSA-351849|Reactome:R-HSA-5660663|Reactome:R-HSA-9013895|Reactome:R-HSA-212552|Reactome:R-HSA-350651|Reactome:R-HSA-114259 go-plus.json thiol endopeptidase activity|metacaspase activity|caspase activity|lysosomal cysteine-type endopeptidase http://purl.obolibrary.org/obo/GO_0004197 GO:0102662 biolink:MolecularActivity malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity Catalysis of the reaction: 3-oxopropanoate + coenzyme A(4-) + NAD(1-) <=> acetyl-CoA(4-) + carbon dioxide + NADH(2-). MetaCyc:RXN-2902|RHEA:22992 go-plus.json http://purl.obolibrary.org/obo/GO_0102662 GO:0102665 biolink:MolecularActivity indole-3-acetyl-glutamate synthetase activity Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP <=> H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid. MetaCyc:RXN-2947 go-plus.json http://purl.obolibrary.org/obo/GO_0102665 GO:0102664 biolink:MolecularActivity indole-3-acetyl-leucine synthetase activity Catalysis of the reaction: indole-3-acetate + L-leucine + ATP <=> H+ + indole-3-acetyl-leucine + diphosphoric acid + AMP. MetaCyc:RXN-2945 go-plus.json http://purl.obolibrary.org/obo/GO_0102664 GO:0004199 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004199 GO:0004194 biolink:MolecularActivity obsolete pepsin A activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin. go-plus.json lactated pepsin elixir|P I|pepsin A activity|elixir lactate of pepsin|P II|pepsin R|pepsin activity|fundus-pepsin|lactated pepsin|pepsin D|pepsin fortior http://purl.obolibrary.org/obo/GO_0004194 GO:0102667 biolink:MolecularActivity indole-3-acetyl-beta-1-D-glucose hydrolase activity Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose. MetaCyc:RXN-3165 go-plus.json http://purl.obolibrary.org/obo/GO_0102667 GO:0004193 biolink:MolecularActivity obsolete cathepsin E activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity. go-plus.json cathepsin E activity|non-pepsin proteinase activity|erythrocyte membrane aspartic proteinase activity|slow-moving proteinase activity|cathepsin E-like acid proteinase activity|EMAP|cathepsin D-like acid proteinase activity|SMP|cathepsin D-type proteinase activity http://purl.obolibrary.org/obo/GO_0004193 GO:0102666 biolink:MolecularActivity indole-3-acetyl-beta-4-D-glucose hydrolase activity Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose. MetaCyc:RXN-3164 go-plus.json http://purl.obolibrary.org/obo/GO_0102666 GO:0004196 biolink:MolecularActivity obsolete saccharopepsin activity OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24. go-plus.json Saccharomyces aspartic proteinase activity|aspartic proteinase yscA|saccharopepsin activity|PRA|saccharomyces aspartic proteinase activity|yeast proteinase A|yeast endopeptidase A activity|saccharomyces cerevisiae aspartic proteinase A|proteinase A|proteinase yscA http://purl.obolibrary.org/obo/GO_0004196 GO:0102669 biolink:MolecularActivity isoflavone-7-O-glucoside beta-glucosidase activity Catalysis of the reaction: daidzein 7-O-beta-D-glucoside + H2O <=> daidzein + beta-D-glucose. MetaCyc:RXN-3591 go-plus.json http://purl.obolibrary.org/obo/GO_0102669 GO:0004195 biolink:MolecularActivity obsolete renin activity OBSOLETE. Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I. go-plus.json renin activity|angiotensin-forming enzyme activity|angiotensinogenase activity http://purl.obolibrary.org/obo/GO_0004195 GO:0102668 biolink:MolecularActivity liquiritigenin,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: liquiritigenin + NADPH + O2 + H+ <=> 2,4',7-trihydroxyisoflavanone + NADP(3-) + H2O. EC:1.14.14.87|RHEA:31723|MetaCyc:RXN-3283 go-plus.json http://purl.obolibrary.org/obo/GO_0102668 CHEBI:6887 biolink:ChemicalSubstance methylphenidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_6887 CHEBI:138691 biolink:ChemicalSubstance 9-cis-retinyl tetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138691 chebi_ph7_3 GO:0004169 biolink:MolecularActivity dolichyl-phosphate-mannose-protein mannosyltransferase activity Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein. EC:2.4.1.109|Reactome:R-HSA-5615604|Reactome:R-HSA-5615556|Reactome:R-HSA-5615637|MetaCyc:2.4.1.109-RXN go-plus.json O-glycoside mannosyltransferase|dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity|dolichyl-phosphate-mannose-protein O-mannosyltransferase activity|protein O-D-mannosyltransferase activity|dolichol phosphomannose-protein mannosyltransferase activity|protein O-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0004169 GO:0004168 biolink:MolecularActivity dolichol kinase activity Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate. RHEA:13133|Reactome:R-HSA-4755600|MetaCyc:DOLICHOL-KINASE-RXN|EC:2.7.1.108|Reactome:R-HSA-446195 go-plus.json CTP:dolichol O-phosphotransferase activity|dolichol phosphokinase activity http://purl.obolibrary.org/obo/GO_0004168 GO:0004165 biolink:MolecularActivity dodecenoyl-CoA delta-isomerase activity Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA. Reactome:R-HSA-109338|Reactome:R-HSA-6809808|MetaCyc:ENOYL-COA-DELTA-ISOM-RXN|RHEA:23716|EC:5.3.3.8 go-plus.json 3,2-trans-enoyl-CoA isomerase activity|dodecenoyl-CoA isomerase activity|acetylene-allene isomerase activity|dodecenoyl-CoA Delta-isomerase activity|delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity|dodecenoyl-CoA (3Z)-(2E)-isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|delta3,Delta2-enoyl-CoA isomerase activity|dodecenoyl-CoA D-isomerase activity|delta(3),Delta(2)-enoyl-CoA isomerase activity|dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity http://purl.obolibrary.org/obo/GO_0004165 GO:0004164 biolink:MolecularActivity diphthine synthase activity Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine. MetaCyc:RXN-11370|EC:2.1.1.98|RHEA:20145|Reactome:R-HSA-5358484 go-plus.json S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity|diphthine methyltransferase activity|S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity http://purl.obolibrary.org/obo/GO_0004164 GO:0004167 biolink:MolecularActivity dopachrome isomerase activity Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate. KEGG_REACTION:R03673|RHEA:13041|MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN|EC:5.3.3.12 go-plus.json DCF activity|dopachrome conversion activity|dopachrome delta7,Delta2-isomerase activity|dopachrome-rearranging enzyme|TRP2|tyrosinase-related protein 2 activity|dopachrome tautomerase activity|dopachrome keto-enol isomerase activity|TRP activity|L-dopachrome keto-enol isomerase activity|dopachrome rearranging enzyme activity|dopachrome conversion factor activity|DCT activity|L-dopachrome isomerase activity|TRP-2|dopachrome Delta(7),Delta(2)-isomerase activity|TRP-1|tryosinase-related protein-2|dopachrome oxidoreductase activity|dopachrome delta-isomerase activity|L-dopachrome-methyl ester tautomerase activity http://purl.obolibrary.org/obo/GO_0004167 GO:0004166 biolink:MolecularActivity dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate. MetaCyc:2.4.1.153-RXN|RHEA:14693|EC:2.4.1.153 go-plus.json UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity|dolichyl-phosphate acetylglucosaminyltransferase activity|dolichyl-phosphate N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity|dolichyl phosphate acetylglucosaminyltransferase activity|dolichyl phosphate N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0004166 GO:0004161 biolink:MolecularActivity dimethylallyltranstransferase activity Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. EC:2.5.1.1|Reactome:R-HSA-191322|RHEA:22408|MetaCyc:GPPSYN-RXN go-plus.json (2E,6E)-farnesyl diphosphate synthetase activity|trans-farnesyl pyrophosphate synthetase activity|geranyl-diphosphate synthase activity|dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity|geranyl pyrophosphate synthetase activity|DMAPP:IPP-dimethylallyltransferase activity|dimethylallyltransferase activity|diprenyltransferase activity|geranyl pyrophosphate synthase activity|geranyl diphosphate synthase http://purl.obolibrary.org/obo/GO_0004161 GO:0004160 biolink:MolecularActivity dihydroxy-acid dehydratase activity Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O. MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN|RHEA:20936|EC:4.2.1.9 go-plus.json alpha,beta-dihydroxyisovalerate dehydratase activity|2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)|acetohydroxyacid dehydratase activity|2,3-dihydroxyisovalerate dehydratase activity|alpha,beta-dihydroxyacid dehydratase activity|2,3-dihydroxy-acid hydro-lyase activity|dihydroxy acid dehydrase activity|DHAD http://purl.obolibrary.org/obo/GO_0004160 GO:0004163 biolink:MolecularActivity diphosphomevalonate decarboxylase activity Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate. Reactome:R-HSA-191414|EC:4.1.1.33|RHEA:23732|MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN|KEGG_REACTION:R01121 go-plus.json mevalonate-5-pyrophosphate decarboxylase activity|pyrophosphomevalonate decarboxylase activity|mevalonate pyrophosphate decarboxylase activity|mevalonate diphosphate decarboxylase activity|5-pyrophosphomevalonate decarboxylase activity|mevalonate 5-diphosphate decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)|pyrophosphomevalonic acid decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming) http://purl.obolibrary.org/obo/GO_0004163 GO:0004162 biolink:MolecularActivity dimethylnitrosamine demethylase activity Catalysis of the removal of a methyl group from N-nitrosodimethylamine. go-plus.json N-nitrosodimethylamine demethylase activity http://purl.obolibrary.org/obo/GO_0004162 GO:0004170 biolink:MolecularActivity dUTP diphosphatase activity Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate. Reactome:R-HSA-73666|RHEA:10248|EC:3.6.1.23|KEGG_REACTION:R02100|MetaCyc:DUTP-PYROP-RXN go-plus.json desoxyuridine 5'-triphosphatase activity|dUTPase activity|dUTP nucleotidohydrolase activity|dUTP pyrophosphatase activity|desoxyuridine 5'-triphosphate nucleotidohydrolase activity|deoxyuridine-triphosphatase activity http://purl.obolibrary.org/obo/GO_0004170 goslim_chembl CHEBI:138661 biolink:ChemicalSubstance N-hexadecanoyl-O-(1-octadecanoyl-2-oleoyl-sn-glycero-3-phospho)-L-serine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138661 chebi_ph7_3 CHEBI:138660 biolink:ChemicalSubstance dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_138660 CHEBI:138664 biolink:ChemicalSubstance N-(omega-hydroxytriacontanoyl)sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138664 chebi_ph7_3 CHEBI:138663 biolink:ChemicalSubstance N-hexadecanoyl-1-[(1Z)-octadecenoyl]-2-oleoyl-sn-glycero-3-phosphoethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138663 chebi_ph7_3 CHEBI:138662 biolink:ChemicalSubstance N-hexadecanoyl-O-(1-octadecanoyl-sn-glycero-3-phospho)-L-serine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138662 chebi_ph7_3 GO:0004179 biolink:MolecularActivity obsolete membrane alanyl aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide. EC:3.4.11.2|MetaCyc:3.4.11.2-RXN go-plus.json membrane aminopeptidase I activity|alanyl aminopeptidase activity|cysteinylglycinase activity|L-alanine aminopeptidase activity|amino-oligopeptidase activity|membrane alanine aminopeptidase activity|microsomal aminopeptidase activity|particle-bound aminopeptidase activity|membrane alanyl aminopeptidase activity|aminopeptidase M activity|cysteinylglycine dipeptidase activity|aminopeptidase N activity|alanine-specific aminopeptidase activity|peptidase E activity|pseudo leucine aminopeptidase activity|CD13 http://purl.obolibrary.org/obo/GO_0004179 GO:0004176 biolink:MolecularActivity ATP-dependent peptidase activity Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis. Reactome:R-HSA-9698929 go-plus.json ATP-dependent proteolysis http://purl.obolibrary.org/obo/GO_0004176 GO:0004175 biolink:MolecularActivity endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. Reactome:R-HSA-5358460|Reactome:R-HSA-5387392|Reactome:R-HSA-5668520|Reactome:R-HSA-1236970|Reactome:R-HSA-450466|Reactome:R-HSA-69016|Reactome:R-HSA-69600|Reactome:R-HSA-5693081|EC:3.4.99.-|Reactome:R-HSA-5668481|Reactome:R-HSA-68825|Reactome:R-HSA-9011313|Reactome:R-HSA-1168640|Reactome:R-HSA-174203|Reactome:R-HSA-180573|Reactome:R-HSA-5358340|Reactome:R-HSA-174255|Reactome:R-HSA-9614271|Reactome:R-HSA-5607731|Reactome:R-HSA-5687112|Reactome:R-HSA-74730|Reactome:R-HSA-4641256|Reactome:R-HSA-6784676|Reactome:R-HSA-8854044|Reactome:R-HSA-353125|Reactome:R-HSA-8850992|Reactome:R-HSA-8849797|Reactome:R-HSA-6784628|Reactome:R-HSA-4641260|Reactome:R-HSA-8866553|Reactome:R-HSA-9009362|Reactome:R-HSA-1251997|Reactome:R-HSA-5610758|Reactome:R-HSA-8854071|Reactome:R-HSA-174202|Reactome:R-HSA-187574|Reactome:R-HSA-8866858|MetaCyc:RXN0-5195|Reactome:R-HSA-3928656|Reactome:R-HSA-5658430|Reactome:R-HSA-5607724|Reactome:R-HSA-5635868|Reactome:R-HSA-5635854|Reactome:R-HSA-2130282|Reactome:R-HSA-983158|Reactome:R-HSA-8852354|Reactome:R-HSA-1234159|Reactome:R-HSA-180603|Reactome:R-HSA-8934819|Reactome:R-HSA-5362448|Reactome:R-HSA-983150|Reactome:R-HSA-8957265|Reactome:R-HSA-174058|Reactome:R-HSA-75825|Reactome:R-HSA-264458|Reactome:R-HSA-1433374|Reactome:R-HSA-68948|Reactome:R-HSA-5610754|Reactome:R-HSA-5610757|Reactome:R-HSA-211715|Reactome:R-HSA-209061|Reactome:R-HSA-188191|Reactome:R-HSA-8939801|Reactome:R-HSA-193682|Reactome:R-HSA-9010096|Reactome:R-HSA-2213200|Reactome:R-HSA-1236935|Reactome:R-HSA-1504193|Reactome:R-HSA-9604642|Reactome:R-HSA-9008475|Reactome:R-HSA-4608855|Reactome:R-HSA-3640874|Reactome:R-HSA-174105|Reactome:R-HSA-9008110|Reactome:R-HSA-5610760|Reactome:R-HSA-8952408 go-plus.json proteinase|proteasome endopeptidase activity|endoprotease activity|elastase activity http://purl.obolibrary.org/obo/GO_0004175 GO:0004178 biolink:MolecularActivity obsolete leucyl aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro. EC:3.4.11.1|MetaCyc:3.4.11.1-RXN go-plus.json leucinamide aminopeptidase activity|aminopeptidase II|FTBL proteins|cytosol aminopeptidase activity|leucyl peptidase activity|proteinates FTBL|leucyl aminopeptidase activity|peptidase S activity|leucine aminopeptidase activity|L-leucine aminopeptidase activity|cathepsin III|leucinaminopeptidase activity http://purl.obolibrary.org/obo/GO_0004178 GO:0004177 biolink:MolecularActivity aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain. MetaCyc:3.4.11.9-RXN|EC:3.4.11.-|MetaCyc:3.4.11.6-RXN|MetaCyc:3.4.11.5-RXN|MetaCyc:RXN0-5052|Reactome:R-HSA-1236954|MetaCyc:3.4.11.21-RXN|Reactome:R-HSA-2534096|EC:3.4.11.9|EC:3.4.11.21|EC:3.4.11.6|EC:3.4.11.5|Reactome:R-HSA-983162|Reactome:R-HSA-8851929 go-plus.json http://purl.obolibrary.org/obo/GO_0004177 GO:0004172 biolink:MolecularActivity obsolete ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity http://purl.obolibrary.org/obo/GO_0004172 GO:0102601 biolink:MolecularActivity cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity Catalysis of the reaction: beta-amyrin + O2 + H+ + NADPH = 16beta-hydroxy-beta-amyrin + H2O + NADP. RHEA:55440|EC:1.14.14.63|MetaCyc:RXN-15385 go-plus.json http://purl.obolibrary.org/obo/GO_0102601 GO:0102600 biolink:MolecularActivity cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity Catalysis of the reaction: 12,13beta-epoxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P). MetaCyc:RXN-15384 go-plus.json http://purl.obolibrary.org/obo/GO_0102600 GO:0004171 biolink:MolecularActivity obsolete deoxyhypusine synthase activity OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. go-plus.json deoxyhypusine synthase activity|[eIF-5A]-deoxyhypusine synthase http://purl.obolibrary.org/obo/GO_0004171 GO:0004174 biolink:MolecularActivity electron-transferring-flavoprotein dehydrogenase activity Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein]. MetaCyc:1.5.5.1-RXN|Reactome:R-HSA-169270|EC:1.5.5.1|RHEA:24052 go-plus.json electron transfer flavoprotein reductase activity|ETF dehydrogenase activity|electron transfer flavoprotein-ubiquinone oxidoreductase activity|electron-transferring-flavoprotein:ubiquinone oxidoreductase activity|ETF:ubiquinone oxidoreductase activity|ETF-QO activity|electron transfer flavoprotein dehydrogenase activity|ETF-ubiquinone oxidoreductase activity|electron transfer flavoprotein Q oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004174 GO:0102603 biolink:MolecularActivity 12-demethyl-elloramycin C12a O-methyltransferase activity Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine <=> elloramycin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15402 go-plus.json http://purl.obolibrary.org/obo/GO_0102603 GO:0102602 biolink:MolecularActivity cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P). MetaCyc:RXN-15386 go-plus.json http://purl.obolibrary.org/obo/GO_0102602 GO:0004173 biolink:MolecularActivity ecdysone O-acyltransferase activity Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate. RHEA:15217|KEGG_REACTION:R02375|EC:2.3.1.139|MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN go-plus.json palmitoyl-CoA:ecdysone palmitoyltransferase activity|fatty acyl-CoA:ecdysone acyltransferase activity|acyl-CoA:ecdysone acyltransferase activity http://purl.obolibrary.org/obo/GO_0004173 GO:0102605 biolink:MolecularActivity cyclooctat-9-en-5,7-diol C18-monooxygenase activity Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP. RHEA:56824|MetaCyc:RXN-15430 go-plus.json http://purl.obolibrary.org/obo/GO_0102605 GO:0102604 biolink:MolecularActivity naringenin,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: (S)-naringenin(1-) + O2 + NADPH + H+ <=> 2-hydroxy-2,3-dihydrogenistein-7-olate + NADP + H2O. RHEA:35487|MetaCyc:RXN-1541|EC:1.14.14.87 go-plus.json http://purl.obolibrary.org/obo/GO_0102604 GO:0004181 biolink:MolecularActivity metallocarboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. MetaCyc:CARBOXYPEPTIDASE-B-RXN|EC:3.4.17.6|MetaCyc:CARBOXYPEPTIDASE-A-RXN|EC:3.4.17.4|EC:3.4.17.17|MetaCyc:3.4.17.22-RXN|EC:3.4.17.3|EC:3.4.17.2|Reactome:R-HSA-2022379|EC:3.4.17.1|Reactome:R-HSA-2022378|MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN|EC:3.4.17.22|EC:3.4.17.10|EC:3.4.17.21|MetaCyc:LYSINEARGININE-CARBOXYPEPTIDASE-RXN|EC:3.4.17.-|MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN|Reactome:R-HSA-9023159|Reactome:R-HSA-8866105|Reactome:R-HSA-9023163|MetaCyc:CARBOXYPEPTIDASE-H-RXN|MetaCyc:3.4.17.17-RXN|Reactome:R-HSA-8955712|Reactome:R-HSA-2028294|Reactome:R-HSA-8852809 go-plus.json http://purl.obolibrary.org/obo/GO_0004181 GO:0102607 biolink:MolecularActivity 3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O. MetaCyc:RXN-15433 go-plus.json http://purl.obolibrary.org/obo/GO_0102607 GO:0004180 biolink:MolecularActivity carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain. MetaCyc:3.4.17.11-RXN|EC:3.4.17.11|Reactome:R-HSA-1247910|RHEA:28783 go-plus.json http://purl.obolibrary.org/obo/GO_0004180 GO:0102606 biolink:MolecularActivity octat-9-en-7-ol 5-monooxygenase activity Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP. RHEA:56820|MetaCyc:RXN-15431 go-plus.json http://purl.obolibrary.org/obo/GO_0102606 GO:0102609 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102609 GO:0102608 biolink:MolecularActivity tetracenomycin B3 8-O-methyl transferase activity Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine <=> tetracenomycin E + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15435 go-plus.json http://purl.obolibrary.org/obo/GO_0102608 CHEBI:138676 biolink:ChemicalSubstance 11-cis-retinyl tetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138676 chebi_ph7_3 CHEBI:138675 biolink:ChemicalSubstance gas molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_138675 GO:0004147 biolink:MolecularActivity dihydrolipoamide branched chain acyltransferase activity Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain. go-plus.json dihydrolipoamide branched chain transacylase activity http://purl.obolibrary.org/obo/GO_0004147 GO:0004146 biolink:MolecularActivity dihydrofolate reductase activity Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. RHEA:15009|EC:1.5.1.3|Reactome:R-HSA-1497794|MetaCyc:DIHYDROFOLATEREDUCT-RXN go-plus.json dihydrofolic acid reductase activity|dihydrofolate reduction|7,8-dihydrofolate reductase activity|dihydrofolic reductase activity|pteridine reductase:dihydrofolate reductase activity|NADPH-dihydrofolate reductase activity|thymidylate synthetase-dihydrofolate reductase activity|folic reductase activity|5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity|dihydrofolate reductase:thymidylate synthase activity|folic acid reductase activity|DHFR|tetrahydrofolate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004146 GO:0004149 biolink:MolecularActivity dihydrolipoyllysine-residue succinyltransferase activity Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide. EC:2.3.1.61|RHEA:15213 go-plus.json lipoyl transsuccinylase activity|succinyl-CoA:dihydrolipoamide S-succinyltransferase activity|lipoate succinyltransferase activity|dihydrolipoamide succinyltransferase activity|enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity|dihydrolipoamide S-succinyltransferase activity|dihydrolipoic transsuccinylase activity|succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity|succinyl-CoA:dihydrolipoate S-succinyltransferase activity|dihydrolipoyl transsuccinylase activity|dihydrolipolyl transsuccinylase activity|succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity|lipoate succinyltransferase (Escherichia coli) activity|lipoic transsuccinylase activity http://purl.obolibrary.org/obo/GO_0004149 GO:0004148 biolink:MolecularActivity dihydrolipoyl dehydrogenase activity Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+. MetaCyc:DIHYDLIPOXN-RXN|EC:1.8.1.4|Reactome:R-HSA-1222412|RHEA:15045|Reactome:R-HSA-5694018 go-plus.json E3 component of alpha-ketoacid dehydrogenase complexes activity|dihydrolipoamide reduction|glycine-cleavage system L-protein activity|lipoate dehydrogenase activity|dihydrolipoamide dehydrogenase activity|lipoamide reductase (NADH) activity|dihydrolipoic dehydrogenase activity|dihydrolipoylprotein reduction|lipoamide dehydrogenase (NADH) activity|dehydrolipoate dehydrogenase activity|lipoic acid dehydrogenase activity|lipoamide oxidoreductase (NADH) activity|dihydrolipoamide:NAD+ oxidoreductase|protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase|diaphorase activity|LDP-Glc activity|protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase|lipoamide reductase activity|lipoyl dehydrogenase activity|LDP-Val activity|L-protein activity|dihydrothioctic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004148 GO:0004143 biolink:MolecularActivity diacylglycerol kinase activity Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate. EC:2.7.1.107|RHEA:10272|MetaCyc:DIACYLGLYKIN-RXN|Reactome:R-HSA-426240 go-plus.json diacylglycerol:ATP kinase activity|DGK activity|sn-1,2-diacylglycerol kinase activity|1,2-diacylglycerol kinase (phosphorylating)|CTP:diacylglycerol kinase activity|ATP:diacylglycerol phosphotransferase activity|ATP:1,2-diacylglycerol 3-phosphotransferase activity|diglyceride kinase activity|1,2-diacylglycerol kinase activity|arachidonoyl-specific diacylglycerol kinase activity|DG kinase activity http://purl.obolibrary.org/obo/GO_0004143 GO:0004142 biolink:MolecularActivity diacylglycerol cholinephosphotransferase activity Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine. Reactome:R-HSA-1482973|RHEA:32939|MetaCyc:RXN-5781|EC:2.7.8.2|Reactome:R-HSA-1482961 go-plus.json phosphorylcholine--glyceride transferase activity|CDP-choline diglyceride phosphotransferase activity|sn-1,2-diacylglycerol cholinephosphotransferase activity|cytidine diphosphorylcholine diglyceride transferase activity|CPT|cholinephosphotransferase activity|alkylacylglycerol cholinephosphotransferase activity|alkylacylglycerol choline phosphotransferase activity|CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity|1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity|cytidine diphosphocholine glyceride transferase activity|phosphocholine diacylglyceroltransferase activity|1-alkyl-2-acetylglycerol cholinephosphotransferase activity|diacylglycerol choline phosphotransferase activity|1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity http://purl.obolibrary.org/obo/GO_0004142 GO:0004145 biolink:MolecularActivity diamine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine. Reactome:R-HSA-351208|RHEA:25181|MetaCyc:DIAMACTRANS-RXN|Reactome:R-HSA-351207|EC:2.3.1.57 go-plus.json spermidine acetyltransferase activity|spermidine N(1)-acetyltransferase activity|acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity|spermine acetyltransferase|putrescine (diamine)-acetylating enzyme activity|putrescine acetyltransferase activity|putrescine N-acetyltransferase activity|spermine N-acetyltransferase|diamine acetyltransferase activity|spermidine/spermine N1-acetyltransferase activity|putrescine acetylase activity|acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity|spermidine N1-acetyltransferase activity|spermine N(1)-acetyltransferase http://purl.obolibrary.org/obo/GO_0004145 GO:0102610 biolink:MolecularActivity (+)-secoisolariciresinol glucosyltransferase activity Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+. MetaCyc:RXN-15442 go-plus.json http://purl.obolibrary.org/obo/GO_0102610 GO:0004144 biolink:MolecularActivity diacylglycerol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol. MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|Reactome:R-HSA-1482889|Reactome:R-HSA-8848580|RHEA:10868|Reactome:R-HSA-75900|Reactome:R-HSA-549192|EC:2.3.1.20 go-plus.json diacylglycerol acyltransferase activity|palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity|acyl-CoA:1,2-diacylglycerol O-acyltransferase activity|1,2-diacylglycerol acyltransferase activity|diglyceride acyltransferase activity|diglyceride O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0004144 GO:0102612 biolink:MolecularActivity syn-pimaradiene 6beta-hydroxylase activity Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O. MetaCyc:RXN-15452 go-plus.json http://purl.obolibrary.org/obo/GO_0102612 GO:0102611 biolink:MolecularActivity (+)-secoisolariciresinol monoglucoside glucosyltransferase activity Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+. MetaCyc:RXN-15443 go-plus.json http://purl.obolibrary.org/obo/GO_0102611 GO:0102614 biolink:MolecularActivity germacrene A acid 8beta-hydroxylase activity Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O. MetaCyc:RXN-15460 go-plus.json http://purl.obolibrary.org/obo/GO_0102614 GO:0004141 biolink:MolecularActivity dethiobiotin synthase activity Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate. EC:6.3.3.3|KEGG_REACTION:R03182|MetaCyc:DETHIOBIOTIN-SYN-RXN|RHEA:15805 go-plus.json DTB synthetase activity|desthiobiotin synthase activity|7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0004141 GO:0004140 biolink:MolecularActivity dephospho-CoA kinase activity Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+). KEGG_REACTION:R00130|RHEA:18245|MetaCyc:DEPHOSPHOCOAKIN-RXN|Reactome:R-HSA-196773|EC:2.7.1.24 go-plus.json dephosphocoenzyme A kinase (phosphorylating)|ATP:dephospho-CoA 3'-phosphotransferase activity|3'-dephospho-CoA kinase activity|dephosphocoenzyme A kinase activity http://purl.obolibrary.org/obo/GO_0004140 GO:0102613 biolink:MolecularActivity trimethyluric acid monooxygenase activity Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O. MetaCyc:RXN-15454|RHEA:48992 go-plus.json http://purl.obolibrary.org/obo/GO_0102613 GO:0102616 biolink:MolecularActivity oryzalexin A synthase activity Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin A + H+ + NAD(P)H. MetaCyc:RXN-15464 go-plus.json http://purl.obolibrary.org/obo/GO_0102616 GO:0102615 biolink:MolecularActivity ent-cassadiene-C2-hydroxylase activity Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O. MetaCyc:RXN-15462|RHEA:55484 go-plus.json http://purl.obolibrary.org/obo/GO_0102615 GO:0102618 biolink:MolecularActivity oryzalexin B synthase activity Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin B + H+ + NAD(P)H. MetaCyc:RXN-15466 go-plus.json http://purl.obolibrary.org/obo/GO_0102618 GO:0102617 biolink:MolecularActivity oryzalexin C synthase (oryzalexin B dependent) activity Catalysis of the reaction: oryzalexin B + NAD(P) <=> oryzalexin C + H+ + NAD(P)H. MetaCyc:RXN-15465 go-plus.json http://purl.obolibrary.org/obo/GO_0102617 NCBITaxon:31932 biolink:OrganismalEntity Nitrosopumilales go-plus.json marine group1 Crenarchaeota|archaeal group 1|marine archaeal group 1|marine group1 Thaumarchaeota|Archaeobacterium group 1 http://purl.obolibrary.org/obo/NCBITaxon_31932 GO:0018788 biolink:MolecularActivity atrazine chlorohydrolase activity Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+). MetaCyc:3.8.1.8-RXN|UM-BBD_reactionID:r0113|EC:3.8.1.8|KEGG_REACTION:R05558|RHEA:11312 go-plus.json AtzA http://purl.obolibrary.org/obo/GO_0018788 GO:0102619 biolink:MolecularActivity oryzalexin C synthase (oryzalexin A dependent) activity Catalysis of the reaction: oryzalexin A + NAD(P) <=> oryzalexin C + H+ + NAD(P)H. MetaCyc:RXN-15467 go-plus.json http://purl.obolibrary.org/obo/GO_0102619 GO:0018787 biolink:MolecularActivity 4-chlorobenzoyl-CoA dehalogenase activity Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride. UM-BBD_enzymeID:e0113|MetaCyc:3.8.1.7-RXN|EC:3.8.1.7|RHEA:14853 go-plus.json 4-chlorobenzoyl CoA chlorohydrolase activity http://purl.obolibrary.org/obo/GO_0018787 GO:0018789 biolink:MolecularActivity cyclamate sulfohydrolase activity Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate. RHEA:18481|EC:3.10.1.2|MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN|UM-BBD_reactionID:r0755|KEGG_REACTION:R02564 go-plus.json cyclamate sulphohydrolase activity|cyclamate sulfamatase activity|cyclamate sulfamidase activity|cyclohexylsulfamate sulfohydrolase activity|cyclohexylsulfamate sulfamidase activity http://purl.obolibrary.org/obo/GO_0018789 GO:0018784 biolink:MolecularActivity (S)-2-haloacid dehalogenase activity Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide. EC:3.8.1.2|UM-BBD_reactionID:r0090|RHEA:11192|MetaCyc:2-HALOACID-DEHALOGENASE-RXN go-plus.json (S)-2-haloacid halidohydrolase activity|2-haloalkanoid acid halidohydrolase activity|2-halocarboxylic acid dehalogenase II activity|DL-2-haloacid dehalogenase activity|2-haloacid halidohydrolase activity|L-2-haloacid dehalogenase activity|2-haloacid dehalogenase activity|halocarboxylic acid halidohydrolase activity|L-DEX activity|2-haloalkanoic acid dehalogenase activity http://purl.obolibrary.org/obo/GO_0018784 GO:0018783 biolink:MolecularActivity deisopropyldeethylatrazine hydrolase activity Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3. go-plus.json http://purl.obolibrary.org/obo/GO_0018783 GO:0018786 biolink:MolecularActivity haloalkane dehalogenase activity Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide. UM-BBD_enzymeID:e0003|RHEA:19081|EC:3.8.1.5|MetaCyc:HALOALKANE-DEHALOGENASE-RXN go-plus.json 1-chlorohexane halidohydrolase activity|1-haloalkane halidohydrolase activity|1-haloalkane dehalogenase activity http://purl.obolibrary.org/obo/GO_0018786 GO:0018785 biolink:MolecularActivity haloacetate dehalogenase activity Catalysis of the reaction: haloacetate + H2O = glycolate + halide. UM-BBD_enzymeID:e0006|MetaCyc:HALOACETATE-DEHALOGENASE-RXN|EC:3.8.1.3|RHEA:11044 go-plus.json haloacetate halidohydrolase activity|monohaloacetate dehalogenase activity http://purl.obolibrary.org/obo/GO_0018785 GO:0018780 biolink:MolecularActivity dichloroacetate halidohydrolase activity Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate. UM-BBD_reactionID:r0383 go-plus.json http://purl.obolibrary.org/obo/GO_0018780 GO:0018782 biolink:MolecularActivity cis-chloroacrylic acid dehalogenase activity Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde. UM-BBD_reactionID:r0688 go-plus.json http://purl.obolibrary.org/obo/GO_0018782 GO:0018781 biolink:MolecularActivity S-triazine hydrolase activity Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine. UM-BBD_enzymeID:e0091 go-plus.json http://purl.obolibrary.org/obo/GO_0018781 CHEBI:138640 biolink:ChemicalSubstance 17(S)-HDoHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_138640 GO:0004158 biolink:MolecularActivity dihydroorotate oxidase activity Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate. RHEA:15441 go-plus.json (S)-dihydroorotate:oxygen oxidoreductase activity|4,5-L-dihydroorotate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0004158 GO:0004157 biolink:MolecularActivity dihydropyrimidinase activity Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate. Reactome:R-HSA-73589|MetaCyc:DIHYDROPYRIMIDINASE-RXN|Reactome:R-HSA-73618|EC:3.5.2.2|RHEA:16121 go-plus.json 5,6-dihydropyrimidine amidohydrolase activity|hydropyrimidine hydrase activity|D-hydantoinase activity|hydantoin peptidase activity|pyrimidine hydrase activity|hydantoinase activity http://purl.obolibrary.org/obo/GO_0004157 NCBITaxon:2283794 biolink:OrganismalEntity Methanomada group go-plus.json Methanogen Class I|Methanomada http://purl.obolibrary.org/obo/NCBITaxon_2283794 GO:0004159 biolink:MolecularActivity dihydropyrimidine dehydrogenase (NAD+) activity Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+. RHEA:20189|EC:1.3.1.1|RHEA:28791|MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN go-plus.json thymine reductase activity|uracil reductase activity|pyrimidine reductase activity|5,6-dihydrouracil:NAD+ oxidoreductase activity|dihydrouracil dehydrogenase (NAD+) activity|dihydrothymine dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0004159 GO:0004154 biolink:MolecularActivity dihydropterin oxidase activity Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide. go-plus.json http://purl.obolibrary.org/obo/GO_0004154 GO:0004153 biolink:MolecularActivity dihydropterin deaminase activity Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3. go-plus.json http://purl.obolibrary.org/obo/GO_0004153 GO:0102621 biolink:MolecularActivity emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O. MetaCyc:RXN-15496 go-plus.json http://purl.obolibrary.org/obo/GO_0102621 GO:0004156 biolink:MolecularActivity dihydropteroate synthase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate. EC:2.5.1.15|RHEA:19949|MetaCyc:H2PTEROATESYNTH-RXN go-plus.json 7,8-dihydropteroate synthetase activity|(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|dihydropteroic synthetase activity|7,8-dihydropteroate synthase activity|7,8-dihydropteroic acid synthetase activity|2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|dihydropteroate pyrophosphorylase activity|dihydropteroate diphosphorylase activity|DHPS activity|dihydropteroate synthetase activity http://purl.obolibrary.org/obo/GO_0004156 GO:0004155 biolink:MolecularActivity 6,7-dihydropteridine reductase activity Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine. Reactome:R-HSA-71130|EC:1.5.1.34|MetaCyc:1.5.1.34-RXN go-plus.json NADPH-specific dihydropteridine reductase activity|5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity|dihydropteridine reduction|NADH-dihydropteridine reductase activity|NAD(P)H2:6,7-dihydropteridine oxidoreductase activity|6,7-dihydropteridine:NAD(P)H oxidoreductase activity|dihydropteridine reductase (NADH) activity|dihydropteridine reductase activity|dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity|5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity|DHPR activity|NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity|NADPH-dihydropteridine reductase activity http://purl.obolibrary.org/obo/GO_0004155 GO:0102620 biolink:MolecularActivity 3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O. MetaCyc:RXN-15495 go-plus.json http://purl.obolibrary.org/obo/GO_0102620 GO:0004150 biolink:MolecularActivity dihydroneopterin aldolase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde. EC:4.1.2.25|RHEA:10540|MetaCyc:H2NEOPTERINALDOL-RXN go-plus.json 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity|2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming) http://purl.obolibrary.org/obo/GO_0004150 GO:0102623 biolink:MolecularActivity scutellarein 7-methyl ether 6-O-methyltransferase activity Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> cirsimaritin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15528 go-plus.json http://purl.obolibrary.org/obo/GO_0102623 GO:0102622 biolink:MolecularActivity linuron hydrolase activity Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline. MetaCyc:RXN-15526 go-plus.json http://purl.obolibrary.org/obo/GO_0102622 GO:0004152 biolink:MolecularActivity dihydroorotate dehydrogenase activity Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate. Reactome:R-HSA-73569|KEGG_REACTION:R01868|MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN|EC:1.3.5.2|RHEA:18073 go-plus.json dihydoorotic acid dehydrogenase activity|dihydroorotate:ubiquinone oxidoreductase activity|(S)-dihydroorotate:quinone oxidoreductase activity|DHOdehase activity|(DHO) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0004152 GO:0102625 biolink:MolecularActivity cirsimaritin 4'-O-methyltransferase activity Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15530 go-plus.json http://purl.obolibrary.org/obo/GO_0102625 GO:0004151 biolink:MolecularActivity dihydroorotase activity Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+). KEGG_REACTION:R01993|EC:3.5.2.3|RHEA:24296|Reactome:R-HSA-73571|MetaCyc:DIHYDROOROT-RXN go-plus.json (S)-dihydroorotate amidohydrolase activity|DHOase activity|dihydroorotate hydrolase activity|carbamoylaspartic dehydrase activity http://purl.obolibrary.org/obo/GO_0004151 GO:0102624 biolink:MolecularActivity scutellarein 7-methyl ether 4'-O-methyltransferase activity Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> ladanein + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15529 go-plus.json http://purl.obolibrary.org/obo/GO_0102624 CHEBI:138658 biolink:ChemicalSubstance dilinoleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138658 chebi_ph7_3 GO:0102627 biolink:MolecularActivity parthenolide 3beta-hydroxylase activity Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O. MetaCyc:RXN-15532 go-plus.json http://purl.obolibrary.org/obo/GO_0102627 CHEBI:138657 biolink:ChemicalSubstance 6-(alpha-D-glucose-1-phospho)-alpha-D-mannoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_138657 GO:0102626 biolink:MolecularActivity parthenolide synthase activity Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O. MetaCyc:RXN-15531 go-plus.json http://purl.obolibrary.org/obo/GO_0102626 CHEBI:138656 biolink:ChemicalSubstance rhizathalene A go-plus.json http://purl.obolibrary.org/obo/CHEBI_138656 chebi_ph7_3 GO:0102629 biolink:MolecularActivity patuletin 3'-O-methyltransferase activity Catalysis of the reaction: patuletin + S-adenosyl-L-methionine <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+. MetaCyc:RXN-15534 go-plus.json http://purl.obolibrary.org/obo/GO_0102629 GO:0102628 biolink:MolecularActivity costunolide 3beta-hydroxylase activity Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O. MetaCyc:RXN-15533 go-plus.json http://purl.obolibrary.org/obo/GO_0102628 GO:0018799 biolink:MolecularActivity 4-hydroxybenzoate decarboxylase activity Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol. EC:4.1.1.61|UM-BBD_reactionID:r0159|RHEA:10876|KEGG_REACTION:R01238|MetaCyc:4-HYDROXYBENZOATE-DECARBOXYLASE-RXN go-plus.json 4-hydroxybenzoate carboxy-lyase activity|p-hydroxybenzoate decarboxylase activity|4-hydroxybenzoate carboxy-lyase (phenol-forming) http://purl.obolibrary.org/obo/GO_0018799 GO:0018798 biolink:MolecularActivity gallate decarboxylase activity Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol. KEGG_REACTION:R03247|MetaCyc:GALLATE-DECARBOXYLASE-RXN|EC:4.1.1.59|RHEA:12749|UM-BBD_reactionID:r0005 go-plus.json gallic acid decarboxylase activity|gallate carboxy-lyase (pyrogallol-forming)|gallate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0018798 GO:0018795 biolink:MolecularActivity 2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate. UM-BBD_reactionID:r0621 go-plus.json http://purl.obolibrary.org/obo/GO_0018795 GO:0018794 biolink:MolecularActivity 2-hydroxyisobutyrate decarboxylase activity Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol. UM-BBD_reactionID:r0617 go-plus.json http://purl.obolibrary.org/obo/GO_0018794 GO:0018797 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018797 GO:0018796 biolink:MolecularActivity 4,5-dihydroxyphthalate decarboxylase activity Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2. RHEA:24184|MetaCyc:45-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|UM-BBD_enzymeID:e0106|EC:4.1.1.55 go-plus.json 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)|4,5-dihydroxyphthalate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0018796 GO:0018791 biolink:MolecularActivity 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate. UM-BBD_reactionID:r0398 go-plus.json http://purl.obolibrary.org/obo/GO_0018791 CHEBI:138654 biolink:ChemicalSubstance (R)-2-hydroxyhexadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138654 chebi_ph7_3 GO:0018790 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018790 GO:0018793 biolink:MolecularActivity 3,5-dibromo-4-hydroxybenzoate decarboxylase activity Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol. UM-BBD_reactionID:r0546 go-plus.json http://purl.obolibrary.org/obo/GO_0018793 CHEBI:138651 biolink:ChemicalSubstance O-(S-fatty acylpantetheine-4'-phosphoryl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138651 chebi_ph7_3 GO:0018792 biolink:MolecularActivity bis(4-chlorophenyl)acetate decarboxylase activity Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM. UM-BBD_reactionID:r0520 go-plus.json DDA decarboxylase activity http://purl.obolibrary.org/obo/GO_0018792 UBERON:0005071 biolink:AnatomicalEntity posterior neuropore The neuropore at the posterior (caudal) end of the neural tube. go-plus.json caudal neuropore http://purl.obolibrary.org/obo/UBERON_0005071 UBERON:0005070 biolink:AnatomicalEntity anterior neuropore The neuropore at the anterior (rostral) end of the neural tube. go-plus.json rostral neuropore|cephalic neuropore|cranial neuropore http://purl.obolibrary.org/obo/UBERON_0005070 GO:0043731 biolink:MolecularActivity 6-hydroxynicotinate 3-monooxygenase activity Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD. MetaCyc:RXN-7573|RHEA:27333|EC:1.14.13.114 go-plus.json http://purl.obolibrary.org/obo/GO_0043731 GO:0043730 biolink:MolecularActivity 5-ureido-4-imidazole carboxylate hydrolase activity Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2. go-plus.json http://purl.obolibrary.org/obo/GO_0043730 CHEBI:68588 biolink:ChemicalSubstance germacrane sesquiterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68588 GO:0043737 biolink:MolecularActivity deoxyribonuclease V activity Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate. MetaCyc:3.1.21.7-RXN|EC:3.1.21.7 go-plus.json Escherichia coli endodeoxyribonuclease V activity|endodeoxyribonuclease V|endonuclease V activity|DNase V activity http://purl.obolibrary.org/obo/GO_0043737 UBERON:0005079 biolink:AnatomicalEntity eggshell A product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration[GO]. go-plus.json egg shell http://purl.obolibrary.org/obo/UBERON_0005079 UBERON:0005078 biolink:AnatomicalEntity lamina terminalis of neural tube The anterior-most (rostral) portion of the wall of the neural tube, formed by closure of the anterior neuropore; the median strip of the anterior wall of the prosencephalon, which persists in a relatively unchanged state as the cerebral hemispheres grow out forward beyond the original anterior end of the prosencephalon. go-plus.json lamina terminalis http://purl.obolibrary.org/obo/UBERON_0005078 GO:0043736 biolink:MolecularActivity obsolete DNA-3-methyladenine glycosylase IV activity OBSOLETE. Catalysis of the hydrolysis of alkylated DNA; recognizes and removes both N-3- and N-7-methyl purines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site. go-plus.json DNA-3-methyladenine glycosylase IV activity|MpgII|Mpg II http://purl.obolibrary.org/obo/GO_0043736 GO:0043739 biolink:MolecularActivity G/U mismatch-specific uracil-DNA glycosylase activity Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site. go-plus.json uracil mismatch repair protein|GU mismatch-specific uracil-DNA glycosylase activity|MUG http://purl.obolibrary.org/obo/GO_0043739 UBERON:0005077 biolink:AnatomicalEntity neuropore A temporary opening leading from the central canal of the embryonic neural tube to the exterior. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005077 GO:0043738 biolink:MolecularActivity reduced coenzyme F420 dehydrogenase activity Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420. MetaCyc:RXN-8106|EC:1.5.98.3|RHEA:54752 go-plus.json F420H2 dehydrogenase activity|1,5-dihydrocoenzyme F420 dehydrogenase activity http://purl.obolibrary.org/obo/GO_0043738 UBERON:0005076 biolink:AnatomicalEntity hindbrain-spinal cord boundary An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord. go-plus.json hindbrain-spinal cord boundary region http://purl.obolibrary.org/obo/UBERON_0005076 UBERON:0005075 biolink:AnatomicalEntity forebrain-midbrain boundary An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain. go-plus.json forebrain midbrain boundary|forebrain-midbrain boundary region|diencephalic-mesencephalic boundary http://purl.obolibrary.org/obo/UBERON_0005075 GO:0043733 biolink:MolecularActivity DNA-3-methylbase glycosylase activity Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site. go-plus.json DNA-3-methyladenine glycosylase III|Mag III|MagIII http://purl.obolibrary.org/obo/GO_0043733 GO:0043732 biolink:MolecularActivity 6-hydroxynicotinate dehydrogenase activity Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2). RHEA:22808|MetaCyc:RXN-7585|EC:1.17.3.3|KEGG_REACTION:R07221 go-plus.json 6-hydroxynicotinic acid dehydrogenase activity|6-hydroxynicotinic acid hydroxylase activity|6-hydroxynicotinate:O2 oxidoreductase activity|6-hydroxynicotinate hydroxylase activity http://purl.obolibrary.org/obo/GO_0043732 GO:0043735 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043735 GO:0043734 biolink:MolecularActivity DNA-N1-methyladenine dioxygenase activity Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde. Reactome:R-HSA-112118|Reactome:R-HSA-112123 go-plus.json AlkB|alpha-ketoglutarate-dependent dioxygenase http://purl.obolibrary.org/obo/GO_0043734 GO:0043740 biolink:MolecularActivity GTP cyclohydrolase IIa activity Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate. MetaCyc:RXN-10055|EC:3.5.4.29|RHEA:22468|KEGG_REACTION:R07306 go-plus.json GTP 8,9-hydrolase (phosphate-forming)|GTP 8,9-dihydrolase (phosphate-forming)|GTP cyclohydrolase III activity http://purl.obolibrary.org/obo/GO_0043740 GO:0043742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043742 GO:0043741 biolink:MolecularActivity alpha-aminoadipate acetyltransferase activity Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A. MetaCyc:RXN-5181 go-plus.json L-2-aminoadipate N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0043741 UBERON:0005068 biolink:AnatomicalEntity neural rod A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. go-plus.json neural tube rod http://purl.obolibrary.org/obo/UBERON_0005068 GO:0043748 biolink:MolecularActivity O-succinylbenzoate synthase activity Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate. EC:4.2.1.113 go-plus.json http://purl.obolibrary.org/obo/GO_0043748 UBERON:0005067 biolink:AnatomicalEntity amphid sensory organ Amphid sensory organs are the sensory organs of nematodes[GO]. go-plus.json amphid sensillum http://purl.obolibrary.org/obo/UBERON_0005067 GO:0043747 biolink:MolecularActivity obsolete N2-acetyl-L-lysine deacetylase activity OBSOLETE. Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine. RHEA:28598|MetaCyc:RXN-5185 go-plus.json N-acetyl-lysine deacetylase activity http://purl.obolibrary.org/obo/GO_0043747 UBERON:0005066 biolink:AnatomicalEntity right ventricular trabecular myocardium . go-plus.json http://purl.obolibrary.org/obo/UBERON_0005066 GO:0043749 biolink:MolecularActivity phenol, water dikinase activity Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate. EC:2.7.9.- go-plus.json phenylphosphate synthase activity|phenol:water dikinase activity|ATP:phenol:water phosphotransferase activity http://purl.obolibrary.org/obo/GO_0043749 UBERON:0005065 biolink:AnatomicalEntity right ventricular compact myocardium . go-plus.json http://purl.obolibrary.org/obo/UBERON_0005065 NCBITaxon:16360 biolink:OrganismalEntity Alismatales go-plus.json Ariflorae|Spathiflorae|Alismatiflorae http://purl.obolibrary.org/obo/NCBITaxon_16360 GO:0043744 biolink:MolecularActivity N2-acetyl-L-aminoadipate kinase activity Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate. RHEA:41944|MetaCyc:RXN-5182 go-plus.json N-acetyl-L-aminoadipate 5-phosphotransferase activity|acetylaminoadipate kinase activity|N-acetylaminoadipate kinase activity|[LysW]-aminoadipate kinase http://purl.obolibrary.org/obo/GO_0043744 UBERON:0005064 biolink:AnatomicalEntity left ventricular trabecular myocardium . go-plus.json http://purl.obolibrary.org/obo/UBERON_0005064 GO:0043743 biolink:MolecularActivity LPPG:FO 2-phospho-L-lactate transferase activity Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP. RHEA:27510|EC:2.7.8.28 go-plus.json http://purl.obolibrary.org/obo/GO_0043743 UBERON:0005063 biolink:AnatomicalEntity left ventricular compact myocardium . go-plus.json http://purl.obolibrary.org/obo/UBERON_0005063 GO:0043746 biolink:MolecularActivity obsolete N2-acetyl-L-lysine aminotransferase activity OBSOLETE. Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine. go-plus.json N-acetyl-lysine aminotransferase activity http://purl.obolibrary.org/obo/GO_0043746 UBERON:0005062 biolink:AnatomicalEntity neural fold One of the two elevated edges of the neural groove[GO,MP]. go-plus.json medullary fold http://purl.obolibrary.org/obo/UBERON_0005062 GO:0043745 biolink:MolecularActivity obsolete N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity OBSOLETE. Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0043745 UBERON:0005061 biolink:AnatomicalEntity neural groove The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005061 CHEBI:20612 biolink:ChemicalSubstance 5-methyltetrahydrofolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20612 UBERON:0005069 biolink:AnatomicalEntity neural fold hinge point The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005069 GO:0043751 biolink:MolecularActivity polyphosphate:AMP phosphotransferase activity Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP. go-plus.json PPT|PAP http://purl.obolibrary.org/obo/GO_0043751 GO:0043750 biolink:MolecularActivity phosphatidylinositol alpha-mannosyltransferase activity Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol. RHEA:47368|EC:2.4.1.345|MetaCyc:2.4.1.57-RXN go-plus.json GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity|phosphatidyl-myo-inositol alpha-mannosyltransferase activity|GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity|GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0043750 GO:0043753 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043753 GO:0043752 biolink:MolecularActivity adenosylcobinamide kinase activity Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP). MetaCyc:2.7.1.156-RXN|EC:2.7.1.156 go-plus.json AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|RTP:adenosylcobinamide phosphotransferase activity|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase|CobU http://purl.obolibrary.org/obo/GO_0043752 GO:0043759 biolink:MolecularActivity methylbutanoate-CoA ligase activity Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = AMP + diphosphate + 2-methylbutanoyl-CoA. RHEA:46180 go-plus.json branched-chain acyl-CoA synthetase (ADP-forming) activity|branched chain acyl-CoA synthetase (ADP-forming) activity|branched-chain acyl CoA synthetase (ADP-forming) activity|branched chain acyl CoA synthetase (ADP-forming) activity http://purl.obolibrary.org/obo/GO_0043759 UBERON:0005057 biolink:AnatomicalEntity immune organ An organ that is part of a immune system [Automatically generated definition]. go-plus.json immune system organ http://purl.obolibrary.org/obo/UBERON_0005057 GO:0043758 biolink:MolecularActivity acetate-CoA ligase (ADP-forming) activity Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA. EC:6.2.1.13|RHEA:15081|MetaCyc:ACETATE--COA-LIGASE-ADP-FORMING-RXN go-plus.json acetyl coenzyme A synthetase (adenosine diphosphate-forming)|acetate thiokinase activity|acetate--CoA ligase (ADP-forming) activity|acetyl-CoA synthetase (ADP-forming) activity|acetate:CoA ligase (ADP-forming)|aryl-CoA synthetase (ADP-forming) activity http://purl.obolibrary.org/obo/GO_0043758 UBERON:0005056 biolink:AnatomicalEntity external female genitalia An external genitalia that is part of a female reproductive system [Automatically generated definition]. go-plus.json female external genitalia|external female genital organ|organa genitalia feminina externa|external genitalia of female reproductive system http://purl.obolibrary.org/obo/UBERON_0005056 NCBITaxon:31979 biolink:OrganismalEntity Clostridiaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_31979 UBERON:0005055 biolink:AnatomicalEntity zone of long bone An organ part that is part of a long bone [Automatically generated definition]. go-plus.json long bone zone http://purl.obolibrary.org/obo/UBERON_0005055 UBERON:0005054 biolink:AnatomicalEntity primary dorsal nerve cord A nerve cord in the dorsal mid-line that is the most prominent nerve cord. go-plus.json dorsal nerve cord|true dorsal nerve cord http://purl.obolibrary.org/obo/UBERON_0005054 GO:0043755 biolink:MolecularActivity alpha-ribazole phosphatase activity Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate. RHEA:24456|EC:3.1.3.73|KEGG_REACTION:R04594|MetaCyc:RIBAZOLEPHOSPHAT-RXN go-plus.json alpha-ribazole-5'-P phosphatase activity|alpha-ribazole-5'-phosphate phosphohydrolase activity|CobC http://purl.obolibrary.org/obo/GO_0043755 UBERON:0005053 biolink:AnatomicalEntity primary nerve cord A cluster of neurons that is the most prominent longitudinally extending condensed part of a nervous system. go-plus.json nerve cord|true nerve cord http://purl.obolibrary.org/obo/UBERON_0005053 GO:0043754 biolink:MolecularActivity dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine. RHEA:18865|MetaCyc:2.3.1.168-RXN|EC:2.3.1.168 go-plus.json 2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity|enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity|2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity|dihydrolipoyl transacylase activity http://purl.obolibrary.org/obo/GO_0043754 UBERON:0005051 biolink:AnatomicalEntity mediastinum testis The mediastinum testis is a network of fibrous connective tissue that extends from the upper to near the lower extremity of the testis, and is wider above than below. From its front and sides numerous imperfect septa (trabeculæ) are given off, which radiate toward the surface of the organ, and are attached to the tunica albuginea. They divide the interior of the organ into a number of incomplete spaces, called lobules. These are somewhat cone-shaped, being broad at their bases at the surface of the gland, and becoming narrower as they converge to the mediastinum. The mediastinum supports the rete testis and blood vessels of the testis in their passage to and from the substance of the gland[WP] go-plus.json body of highmore|testis mediastinum|hilum of testicle|mediastinum of testis http://purl.obolibrary.org/obo/UBERON_0005051 GO:0043757 biolink:MolecularActivity adenosylcobinamide-phosphate synthase activity Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide. MetaCyc:RXN-6261|RHEA:21896|EC:6.3.1.10 go-plus.json CbiB|adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)|AdoCbi-P synthase activity http://purl.obolibrary.org/obo/GO_0043757 GO:0043756 biolink:MolecularActivity adenosylcobinamide hydrolase activity Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate. RHEA:23504|MetaCyc:R346-RXN|KEGG_REACTION:R05226|EC:3.5.1.90 go-plus.json adenosylcobinamide amidohydrolase activity|CbiZ|AdoCbi amidohydrolase activity|AdoCbi hydrolase activity http://purl.obolibrary.org/obo/GO_0043756 UBERON:0005058 biolink:AnatomicalEntity hemolymphoid system gland A gland that is part of a hemolymphoid system [Automatically generated definition]. go-plus.json haemolymphoid system gland|hemopoietic or lymphoid gland|hemopoietic or lymphoid organ http://purl.obolibrary.org/obo/UBERON_0005058 GO:0043762 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043762 GO:0043761 biolink:MolecularActivity archaetidylserine synthase activity Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP. EC:2.7.8.38 go-plus.json CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity|CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity http://purl.obolibrary.org/obo/GO_0043761 GO:0043764 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043764 GO:0043763 biolink:MolecularActivity UTP:glucose-1-phosphate uridylyltransferase regulator activity Binds to and modulates the activity of UTP:glucose-1-phosphate uridylyltransferase. go-plus.json glucose-1-phosphate uridylyltransferase regulator activity|UDP-glucose pyrophosphorylase regulator activity|UDP-glucose diphosphorylase regulator activity http://purl.obolibrary.org/obo/GO_0043763 GO:0043760 biolink:MolecularActivity acetyldiaminopimelate aminotransferase activity Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate. go-plus.json N-acetyl-diaminopimelate aminotransferase activity|N-acetyl-L,L-diaminopimelate aminotransferase activity http://purl.obolibrary.org/obo/GO_0043760 UBERON:0005046 biolink:AnatomicalEntity mucosa of hard palate A mucosa that is part of a hard palate [Automatically generated definition]. go-plus.json hard palate mucosa|organ mucosa of hard palate|hard palate mucous membrane|mucous membrane of hard palate http://purl.obolibrary.org/obo/UBERON_0005046 NCBITaxon:31969 biolink:OrganismalEntity Mollicutes go-plus.json Mycoplasmas and walled relatives|mycoplasmas|Paramycetes http://purl.obolibrary.org/obo/NCBITaxon_31969 GO:0043769 biolink:CellularComponent Tpg-containing telomere binding complex A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species. go-plus.json telomere complex http://purl.obolibrary.org/obo/GO_0043769 GO:0043766 biolink:MolecularActivity Sep-tRNA:Cys-tRNA synthase activity Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate. EC:2.5.1.73|MetaCyc:RXN-10719|RHEA:25686 go-plus.json Sep-tRNA:Cys-tRNA synthetase activity|O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity|SepCysS http://purl.obolibrary.org/obo/GO_0043766 UBERON:0005042 biolink:AnatomicalEntity inner epithelial layer of tympanic membrane A portion of the tympanic cavity epithelium which makes up the outer (cuticular) layer of the tympanic membrane go-plus.json mucous stratum of tympanic membrane|tympanic membrane external middle ear cavity epithelial component|tympanic membrane mucosa|mucosa of tympanic membrane|mucous layer of tympanic membrane http://purl.obolibrary.org/obo/UBERON_0005042 GO:0043765 biolink:MolecularActivity T/G mismatch-specific endonuclease activity Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine. go-plus.json V.EcoKDcm|Vsr mismatch endonuclease|very short patch repair protein|DNA mismatch endonuclease http://purl.obolibrary.org/obo/GO_0043765 CHEBI:19615 biolink:ChemicalSubstance 2-hydroxy-6-oxonona-2,4-dienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19615 chebi_ph7_3 GO:0043768 biolink:MolecularActivity S-ribosylhomocysteine lyase activity Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine. KEGG_REACTION:R01291|MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN|EC:4.4.1.21|RHEA:17753 go-plus.json ribosylhomocysteinase activity|LuxS|S-ribosylhomocysteinase activity|S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming] http://purl.obolibrary.org/obo/GO_0043768 UBERON:0005040 biolink:AnatomicalEntity mucosa of terminal bronchiole A mucosa that is part of a terminal bronchiole [Automatically generated definition]. go-plus.json organ mucosa of bronchiolus terminalis|mucous membrane of terminal bronchiole|bronchiolus terminalis mucosa|terminal bronchiole mucosa|mucosa of organ of terminal bronchiole|mucosa of organ of bronchiolus terminalis|mucosa of bronchiolus terminalis|mucous membrane of bronchiolus terminalis|terminal bronchiole mucosa of organ|organ mucosa of terminal bronchiole|bronchiolus terminalis mucosa of organ|bronchiolus terminalis organ mucosa|terminal bronchiole organ mucosa|terminal bronchiole mucous membrane|bronchiolus terminalis mucous membrane http://purl.obolibrary.org/obo/UBERON_0005040 GO:0043767 biolink:MolecularActivity pyrrolysyl-tRNA synthetase activity Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl). MetaCyc:6.1.1.26-RXN|RHEA:19277|EC:6.1.1.26 go-plus.json PylRS|pyrrolysine-tRNA ligase activity http://purl.obolibrary.org/obo/GO_0043767 UBERON:0005049 biolink:AnatomicalEntity mucosa of infundibulum of uterine tube A mucosa that is part of a uterine tube infundibulum [Automatically generated definition]. go-plus.json mucous membrane of uterine tube infundibulum|mucosa of uterine tube infundibulum|mucosa of organ of uterine tube infundibulum|mucosa of infundibulum of fallopian tube|uterine tube infundibulum organ mucosa|organ mucosa of uterine tube infundibulum|uterine tube infundibulum mucosa of organ|uterine tube infundibulum mucous membrane|uterine tube infundibulum mucosa|mucosa of infundibulum of oviduct http://purl.obolibrary.org/obo/UBERON_0005049 UBERON:0005048 biolink:AnatomicalEntity mucosa of uterine tube A mucosa that is part of a fallopian tube [Automatically generated definition]. go-plus.json fallopian tube mucosa|uterine tube mucosa of organ|mucosa of fallopian tube|mucous membrane of fallopian tube|uterine tube mucosa|uterine tube mucous membrane|fallopian tube mucosa of organ|fallopian tube mucous membrane|organ mucosa of uterine tube|tunica mucosa tubae uterinae|fallopian tube organ mucosa|organ mucosa of fallopian tube|uterine tubal mucosa|uterine tube organ mucosa|mucosa of organ of uterine tube|mucous membrane of uterine tube|mucosa of organ of fallopian tube|mucosa of oviduct http://purl.obolibrary.org/obo/UBERON_0005048 GO:0102670 biolink:MolecularActivity 2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine. RHEA:31371|EC:2.1.1.212|MetaCyc:RXN-3624 go-plus.json http://purl.obolibrary.org/obo/GO_0102670 GO:0102672 biolink:MolecularActivity fatty acid alpha-oxygenase activity Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid. MetaCyc:RXN-4121 go-plus.json http://purl.obolibrary.org/obo/GO_0102672 GO:0102671 biolink:MolecularActivity 6a-hydroxymaackiain-3-O-methyltransferase activity Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine. MetaCyc:RXN-4002|RHEA:35471|EC:2.1.1.270 go-plus.json http://purl.obolibrary.org/obo/GO_0102671 GO:0102674 biolink:MolecularActivity C4-demethylase activity Catalysis of the reaction: 24-methylenelophenol + a demethylated methyl acceptor <=> 9xi-episterol + a methylated methyl acceptor. MetaCyc:RXN-4181 go-plus.json http://purl.obolibrary.org/obo/GO_0102674 GO:0043773 biolink:MolecularActivity coenzyme F420-0 gamma-glutamyl ligase activity Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates. go-plus.json F420-0 gamma-glutamyl ligase activity http://purl.obolibrary.org/obo/GO_0043773 GO:0102673 biolink:MolecularActivity fatty aldehyde dehydrogenase activity Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid. MetaCyc:RXN-4142 go-plus.json http://purl.obolibrary.org/obo/GO_0102673 GO:0043772 biolink:MolecularActivity acyl-phosphate glycerol-3-phosphate acyltransferase activity Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate. go-plus.json acylphosphate:glycerol-3-phosphate acyltransferase activity|acyl-phosphate:glycerol-3-phosphate acyltransferase activity|acylphosphate glycerol-3-phosphate acyltransferase activity http://purl.obolibrary.org/obo/GO_0043772 GO:0043775 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043775 GO:0102676 biolink:MolecularActivity avenasterol-desaturase activity Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP. MetaCyc:RXN-4209 go-plus.json http://purl.obolibrary.org/obo/GO_0102676 GO:0043774 biolink:MolecularActivity coenzyme F420-2 alpha-glutamyl ligase activity Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate. RHEA:42332|EC:6.3.2.32 go-plus.json F420-2 alpha-glutamyl ligase activity http://purl.obolibrary.org/obo/GO_0043774 GO:0102675 biolink:MolecularActivity C4-methyltransferase activity Catalysis of the reaction: 24-ethylidenelophenol + a demethylated methyl acceptor <=> avenasterol + a methylated methyl acceptor. MetaCyc:RXN-4208 go-plus.json http://purl.obolibrary.org/obo/GO_0102675 GO:0102678 biolink:MolecularActivity 22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + NADP <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH. MetaCyc:RXN-4229 go-plus.json http://purl.obolibrary.org/obo/GO_0102678 GO:0102677 biolink:MolecularActivity campesterol,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP. MetaCyc:RXN-4225 go-plus.json http://purl.obolibrary.org/obo/GO_0102677 GO:0043771 biolink:MolecularActivity cytidine kinase activity Catalysis of the reaction: ATP + cytidine = ADP + CMP. go-plus.json http://purl.obolibrary.org/obo/GO_0043771 GO:0043770 biolink:MolecularActivity demethylmenaquinone methyltransferase activity Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine. EC:2.1.1.163 go-plus.json http://purl.obolibrary.org/obo/GO_0043770 GO:0102679 biolink:MolecularActivity (5alpha)-campestan-3-one hydroxylase activity Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP. MetaCyc:RXN-4230 go-plus.json http://purl.obolibrary.org/obo/GO_0102679 GO:0043777 biolink:MolecularActivity cobalt-precorrin-7 C15-methyltransferase activity Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2. RHEA:34591|MetaCyc:RXN-8767 go-plus.json precorrin-6Y methylase|cobalt-precorrin 7 C15-methyltransferase activity|precorrin-6 methyltransferase|precorrin-6Y C5,15-methyltransferase (decarboxylating) http://purl.obolibrary.org/obo/GO_0043777 GO:0043776 biolink:MolecularActivity cobalt-precorrin-6B C5-methyltransferase activity Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7. RHEA:36067|MetaCyc:RXN-8766 go-plus.json cobalt-precorrin 6B C5-methyltransferase activity|precorrin-6 methyltransferase activity|precorrin-6Y methylase|precorrin-6Y C5,15-methyltransferase (decarboxylating) http://purl.obolibrary.org/obo/GO_0043776 GO:0043779 biolink:MolecularActivity cobalt-precorrin-5A acetaldehyde-lyase activity Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde. MetaCyc:RXN-8763|RHEA:26281 go-plus.json cobalt-precorrin 5A acetaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0043779 GO:0043778 biolink:MolecularActivity cobalt-precorrin-8 methylmutase activity Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate. RHEA:16209|EC:5.4.99.60|MetaCyc:RXN-8768 go-plus.json cobalt-precorrin 8X methylmutase activity|cobalt-precorrin-8X methylmutase activity|cobalt-precorrin 8 methylmutase activity http://purl.obolibrary.org/obo/GO_0043778 NCBITaxon:7739 biolink:OrganismalEntity Branchiostoma floridae go-plus.json Florida lancelet|Amphioxus floridae http://purl.obolibrary.org/obo/NCBITaxon_7739 NCBITaxon:7737 biolink:OrganismalEntity Branchiostoma go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7737 NCBITaxon:7736 biolink:OrganismalEntity Branchiostomidae go-plus.json amphioxi|amphioxius|Branchiostomatidae|lancelets http://purl.obolibrary.org/obo/NCBITaxon_7736 GO:0102681 biolink:MolecularActivity isoamylase (maltodextrin-releasing) activity Catalysis of the reaction: n H2O + a glycogen <=> n a maltodextrin. MetaCyc:RXN-4301 go-plus.json http://purl.obolibrary.org/obo/GO_0102681 NCBITaxon:7735 biolink:OrganismalEntity Cephalochordata go-plus.json lancelets http://purl.obolibrary.org/obo/NCBITaxon_7735 GO:0102680 biolink:MolecularActivity campest-4-en-3-one hydroxylase activity Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP. MetaCyc:RXN-4231 go-plus.json http://purl.obolibrary.org/obo/GO_0102680 GO:0102682 biolink:MolecularActivity N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O <=> N(6)-dimethylallyladenine + D-ribofuranose 5-phosphate. RHEA:48560|MetaCyc:RXN-4313 go-plus.json http://purl.obolibrary.org/obo/GO_0102682 GO:0102685 biolink:MolecularActivity UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP. MetaCyc:RXN-4721 go-plus.json http://purl.obolibrary.org/obo/GO_0102685 GO:0043784 biolink:MolecularActivity cob(II)yrinic acid a,c-diamide reductase activity Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2). KEGG_REACTION:R05218|MetaCyc:R343-RXN|EC:1.16.8.1|RHEA:24300 go-plus.json cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity http://purl.obolibrary.org/obo/GO_0043784 GO:0102684 biolink:MolecularActivity L-phenylalanine N-monooxygenase activity Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ <=> (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide. MetaCyc:RXN-4602|EC:1.14.14.40|RHEA:33263 go-plus.json http://purl.obolibrary.org/obo/GO_0102684 GO:0043783 biolink:MolecularActivity oxidoreductase activity, acting on metal ions, flavin as acceptor Catalysis of an oxidation-reduction in which the metal ion is reduced and flavin acts as an electron acceptor. EC:1.16.8.- go-plus.json oxidoreductase activity, reducing metal ions, flavin as acceptor|oxidoreductase activity, oxidizing metal ions with flavin as acceptor http://purl.obolibrary.org/obo/GO_0043783 GO:0043786 biolink:MolecularActivity cinnamate reductase activity Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+. EC:1.3.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0043786 GO:0102687 biolink:MolecularActivity UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP. MetaCyc:RXN-4724 go-plus.json http://purl.obolibrary.org/obo/GO_0102687 GO:0102686 biolink:MolecularActivity UDP-glucose:trans-zeatin 9-N-glucosyltransferase Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin <=> H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-). MetaCyc:RXN-4722 go-plus.json http://purl.obolibrary.org/obo/GO_0102686 GO:0043785 biolink:MolecularActivity cinnamoyl-CoA:phenyllactate CoA-transferase activity Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate. MetaCyc:2.8.3.17-RXN|EC:2.8.3.17|RHEA:15601|KEGG_REACTION:R07796 go-plus.json FldA|(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0043785 GO:0102689 biolink:MolecularActivity UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP. MetaCyc:RXN-4727 go-plus.json http://purl.obolibrary.org/obo/GO_0102689 GO:0043780 biolink:MolecularActivity cobalt-precorrin-5B C1-methyltransferase activity Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A. MetaCyc:RXN-8764|RHEA:26285 go-plus.json cobalt-precorrin 5B C1-methyltransferase activity http://purl.obolibrary.org/obo/GO_0043780 GO:0102688 biolink:MolecularActivity dihydrozeatin UDP glycosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP. MetaCyc:RXN-4725 go-plus.json http://purl.obolibrary.org/obo/GO_0102688 GO:0043782 biolink:MolecularActivity cobalt-precorrin-3 C17-methyltransferase activity Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine. MetaCyc:RXN-8761|RHEA:26273 go-plus.json cobalt-precorrin-3 methyltransferase|cobalt-precorrin 3 C17-methyltransferase activity|cobalt-precorrin-3 methylase|cobalt-precorrin-3B C17-methyltransferase activity http://purl.obolibrary.org/obo/GO_0043782 GO:0043781 biolink:MolecularActivity cobalt-factor II C20-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III. EC:2.1.1.151|MetaCyc:RXN-8760|RHEA:17997 go-plus.json cobalt-precorrin-2 C(20)-methyltransferase activity|S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity|cobalt-factor II C20 methyltransferase activity|CbiL http://purl.obolibrary.org/obo/GO_0043781 GO:0043788 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043788 GO:0043787 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043787 GO:0043789 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043789 NCBITaxon:7742 biolink:OrganismalEntity Vertebrata go-plus.json Vertebrata|vertebrates|vertebrates http://purl.obolibrary.org/obo/NCBITaxon_7742 GO:0102690 biolink:MolecularActivity isopentenyladenine UDP glycosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP. MetaCyc:RXN-4728 go-plus.json http://purl.obolibrary.org/obo/GO_0102690 GO:0102692 biolink:MolecularActivity benzyladenine UDP glycosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP. MetaCyc:RXN-4730 go-plus.json http://purl.obolibrary.org/obo/GO_0102692 GO:0102691 biolink:MolecularActivity UDP-glucose:benzyladenine 7-N-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP. MetaCyc:RXN-4729 go-plus.json http://purl.obolibrary.org/obo/GO_0102691 GO:0102694 biolink:MolecularActivity kinetin UDP glycosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP. MetaCyc:RXN-4732 go-plus.json http://purl.obolibrary.org/obo/GO_0102694 GO:0102693 biolink:MolecularActivity UDP-glucose:kinetin 7-N-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP. MetaCyc:RXN-4731 go-plus.json http://purl.obolibrary.org/obo/GO_0102693 UBERON:0005093 biolink:AnatomicalEntity embryonic cement gland A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm[XAO]. go-plus.json cement gland http://purl.obolibrary.org/obo/UBERON_0005093 GO:0043795 biolink:MolecularActivity glyceraldehyde oxidoreductase activity Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+). RHEA:36047|EC:1.2.99.8 go-plus.json http://purl.obolibrary.org/obo/GO_0043795 GO:0102696 biolink:MolecularActivity cis-zeatin UDP glycosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP. MetaCyc:RXN-4734 go-plus.json http://purl.obolibrary.org/obo/GO_0102696 GO:0043794 biolink:MolecularActivity formate dehydrogenase (coenzyme F420) activity Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420. EC:1.2.99.- go-plus.json formate dehydrogenase (F420) activity http://purl.obolibrary.org/obo/GO_0043794 UBERON:0005092 biolink:AnatomicalEntity right horn of sinus venosus go-plus.json sinus venosus right horn http://purl.obolibrary.org/obo/UBERON_0005092 GO:0102695 biolink:MolecularActivity UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP. MetaCyc:RXN-4733 go-plus.json http://purl.obolibrary.org/obo/GO_0102695 GO:0043797 biolink:MolecularActivity glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin. MetaCyc:1.2.7.6-RXN|RHEA:24148|EC:1.2.7.6 go-plus.json glyceraldehyde-3-phosphate Fd oxidoreductase activity|D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity|glyceraldehyde-3-phosphate ferredoxin reductase activity|GAPOR http://purl.obolibrary.org/obo/GO_0043797 GO:0102698 biolink:MolecularActivity 5-epi-aristolochene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid. MetaCyc:RXN-4781|RHEA:28635|EC:4.2.3.61 go-plus.json http://purl.obolibrary.org/obo/GO_0102698 UBERON:0005091 biolink:AnatomicalEntity left horn of sinus venosus go-plus.json sinus venosus left horn http://purl.obolibrary.org/obo/UBERON_0005091 GO:0043796 biolink:MolecularActivity glyceraldehyde dehydrogenase (NADP) activity Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+. RHEA:40163|EC:1.2.1.89 go-plus.json http://purl.obolibrary.org/obo/GO_0043796 GO:0102697 biolink:MolecularActivity trans-zeatin-O-glucoside UDP glycosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP. MetaCyc:RXN-4736 go-plus.json http://purl.obolibrary.org/obo/GO_0102697 UBERON:0005090 biolink:AnatomicalEntity muscle structure Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. go-plus.json musculus|muscle|muscle element http://purl.obolibrary.org/obo/UBERON_0005090 GO:0043791 biolink:MolecularActivity dimethylamine methyltransferase activity Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine. RHEA:41175|EC:2.1.1.249|MetaCyc:RXN-8100 go-plus.json mtbB1|MT1|dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|dimethylamine:corrinoid methyltransferase activity|DMA methyltransferase 1|DMAMT 1 http://purl.obolibrary.org/obo/GO_0043791 GO:0043790 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043790 GO:0102699 biolink:MolecularActivity 2-methylpropionitrile hydroxylase activity Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O. RHEA:51964|MetaCyc:RXN-5082 go-plus.json http://purl.obolibrary.org/obo/GO_0102699 GO:0043793 biolink:MolecularActivity beta-ribofuranosylaminobenzene 5'-phosphate synthase activity Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate. MetaCyc:RXN-8124 go-plus.json beta-RFAP synthase activity http://purl.obolibrary.org/obo/GO_0043793 OBO:GOCHE_35610 biolink:OntologyClass substance with antineoplastic agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35610 3_STAR GO:0043792 biolink:MolecularActivity enamidase activity Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+). RHEA:17209|KEGG_REACTION:R07984|MetaCyc:3.5.2.18-RXN|EC:3.5.2.18 go-plus.json 6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0043792 PR:000030443 biolink:Protein polyubiquitin-B A polyubiquitin that is a translation product of the human UBB gene or a 1:1 ortholog thereof. go-plus.json UBB http://purl.obolibrary.org/obo/PR_000030443 UBERON:0005099 biolink:AnatomicalEntity short descending thin limb The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005099 GO:0043799 biolink:MolecularActivity glycine oxidase activity Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide. MetaCyc:RXN-8673|MetaCyc:RXN-8672|MetaCyc:1.4.3.19-RXN|EC:1.4.3.19|MetaCyc:RXN-8674 go-plus.json glycine:oxygen oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0043799 UBERON:0005097 biolink:AnatomicalEntity renal connecting tubule The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. go-plus.json connecting tubule|kidney connecting tubule|tubulus renalis arcuatus http://purl.obolibrary.org/obo/UBERON_0005097 UBERON:0005096 biolink:AnatomicalEntity descending thin limb The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle[GO]. go-plus.json thin descending limb of loop of Henle|thin descending loop of Henle|loop of Henle thin descending limb|descending limb of loop of Henle|loop of Henle descending thin limb|thin descending limb|thin descending limb of the loop of Henle|pars descendens (tubulus attenuatus)|descending limb of Henle's loop|descending thin limb of loop of Henle http://purl.obolibrary.org/obo/UBERON_0005096 GO:0043798 biolink:MolecularActivity glycerate 2-kinase activity Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP. MetaCyc:GKI-RXN|RHEA:27377|EC:2.7.1.165 go-plus.json glycerate kinase|D-glycerate 2-kinase activity http://purl.obolibrary.org/obo/GO_0043798 UBERON:0005095 biolink:AnatomicalEntity kidney rudiment . go-plus.json kidney anlage http://purl.obolibrary.org/obo/UBERON_0005095 UBERON:0005094 biolink:AnatomicalEntity beak The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary ramaphotheca, mandibular ramaphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus[GO]. The beak, bill or rostrum is an external anatomical structure of birds which is used for eating and for grooming, manipulating objects, killing prey, probing for food, courtship and feeding young. . go-plus.json avian beak|rostrum|bill http://purl.obolibrary.org/obo/UBERON_0005094 NCBITaxon:7717 biolink:OrganismalEntity Cionidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7717 NCBITaxon:7716 biolink:OrganismalEntity Phlebobranchia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7716 NCBITaxon:7713 biolink:OrganismalEntity Ascidiacea go-plus.json sea squirts|Enterogona http://purl.obolibrary.org/obo/NCBITaxon_7713 NCBITaxon:7712 biolink:OrganismalEntity Tunicata go-plus.json tunicates|tunicates|Urochordata http://purl.obolibrary.org/obo/NCBITaxon_7712 NCBITaxon:7711 biolink:OrganismalEntity Chordata go-plus.json chordates|chordates http://purl.obolibrary.org/obo/NCBITaxon_7711 UBERON:0005082 biolink:AnatomicalEntity tube lumen A hole in a tube[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005082 UBERON:0005081 biolink:AnatomicalEntity ureter ureteric bud The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005081 UBERON:0005080 biolink:AnatomicalEntity metanephric ureteric bud The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005080 OBO:GOCHE_35623 biolink:OntologyClass substance with anticonvulsant role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35623 3_STAR NCBITaxon:7719 biolink:OrganismalEntity Ciona intestinalis go-plus.json Ascidia intestinalis|yellow sea squirt|sea vase|vase tunicate http://purl.obolibrary.org/obo/NCBITaxon_7719 NCBITaxon:7718 biolink:OrganismalEntity Ciona go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7718 UBERON:0005089 biolink:AnatomicalEntity sweat gland placode An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005089 UBERON:0005088 biolink:AnatomicalEntity sebaceous gland placode A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005088 UBERON:0005087 biolink:AnatomicalEntity tooth placode An tooth placode is a thickening of the ectoderm that will give rise to the tooth bud[GO]. go-plus.json dental anlage|odontogenic placode|tooth germ|dental placode|tooth primordium|tooth anlage|dental primordium http://purl.obolibrary.org/obo/UBERON_0005087 UBERON:0005086 biolink:AnatomicalEntity hair follicle placode A bud-like thickening in the epidermis consisting of elongated keratinocytes, which at the distal end are in touch with numerous aggregated specialized dermal fibroblasts, the dermal condensate. go-plus.json hair peg|hair gem|hair placode|vibrissa placode|hair germ http://purl.obolibrary.org/obo/UBERON_0005086 UBERON:0005085 biolink:AnatomicalEntity ectodermal placode An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO] go-plus.json epithelial placode http://purl.obolibrary.org/obo/UBERON_0005085 UBERON:0005083 biolink:AnatomicalEntity nipple sheath A circular ingrowth of the epidermis around the region of the mammary sprout[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005083 CHEBI:68501 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-alpha-D-glucose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68501 chebi_ph7_3 NCBITaxon:41399 biolink:OrganismalEntity Phrymaceae go-plus.json Phrymataceae http://purl.obolibrary.org/obo/NCBITaxon_41399 UBERON:0005111 biolink:AnatomicalEntity metanephric pyramid Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005111 CHEBI:68509 biolink:ChemicalSubstance glutathione depleting agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_68509 UBERON:0005110 biolink:AnatomicalEntity metanephric nephron A metanephric nephron is the functional unit of the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005110 CHEBI:68506 biolink:ChemicalSubstance (S)-3-ammonio-3-phenylpropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68506 chebi_ph7_3 CHEBI:68508 biolink:ChemicalSubstance diethyl maleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68508 chebi_ph7_3 CHEBI:19569 biolink:ChemicalSubstance 2-deoxyribose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19569 CHEBI:68507 biolink:ChemicalSubstance UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68507 CHEBI:19568 biolink:ChemicalSubstance 2-deoxyribose bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19568 CHEBI:20568 biolink:ChemicalSubstance 5-deoxyribose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20568 UBERON:0005119 biolink:AnatomicalEntity metanephric glomerular mesangium The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005119 UBERON:0005118 biolink:AnatomicalEntity metanephric early distal convoluted tubule The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005118 CHEBI:19565 biolink:ChemicalSubstance 2-deoxyribose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19565 CHEBI:20569 biolink:ChemicalSubstance EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_20569 UBERON:0005117 biolink:AnatomicalEntity metanephric distal convoluted tubule The metanephric distal convoluted tubule is a portion of the metanephric nephron tubule that connects the metanephric loop of Henle to the collecting duct[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005117 CHEBI:19564 biolink:ChemicalSubstance 2-deoxyribose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19564 UBERON:0005116 biolink:AnatomicalEntity metanephric descending thin limb It extends to the tip of the metanephric loop of Henle[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005116 UBERON:0005115 biolink:AnatomicalEntity metanephric cortical collecting duct The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005115 UBERON:0005114 biolink:AnatomicalEntity metanephric ascending thin limb The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005114 UBERON:0005113 biolink:AnatomicalEntity metanephric cortex mesenchyme go-plus.json http://purl.obolibrary.org/obo/UBERON_0005113 CHEBI:20570 biolink:ChemicalSubstance 5-hydroxycamphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_20570 chebi_ph7_3 NCBITaxon:7776 biolink:OrganismalEntity Gnathostomata go-plus.json Gnathostomata|jawed vertebrates http://purl.obolibrary.org/obo/NCBITaxon_7776 CHEBI:68510 biolink:ChemicalSubstance lysophosphatidylserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68510 UBERON:0005101 biolink:AnatomicalEntity early distal convoluted tubule The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005101 UBERON:0005100 biolink:AnatomicalEntity long descending thin limb The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005100 CHEBI:68516 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-alpha-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_68516 CHEBI:44526 biolink:ChemicalSubstance (10E,12Z)-octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44526 CHEBI:68518 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_68518 UBERON:0005109 biolink:AnatomicalEntity metanephric smooth muscle tissue Any smooth muscle tissue that is part of a metanephros. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005109 UBERON:0005108 biolink:AnatomicalEntity metanephric epithelium An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005108 UBERON:0005107 biolink:AnatomicalEntity metanephric cap The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip[GO]. Mesenchyme closely apposed to the tips of the buds is called cap mesenchyme; it will later go on to form nephrons etc[GUDMAP]. go-plus.json condensed mesenchyme|cap mesenchyme http://purl.obolibrary.org/obo/UBERON_0005107 CHEBI:19555 biolink:ChemicalSubstance 2-deoxy-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_19555 UBERON:0005106 biolink:AnatomicalEntity metanephric tubule A metanephric tubule is an epithelial tube that is part of the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005106 UBERON:0005105 biolink:AnatomicalEntity posterior mesonephric tubule . go-plus.json caudal mesonephric tubule http://purl.obolibrary.org/obo/UBERON_0005105 UBERON:0005104 biolink:AnatomicalEntity anterior mesonephric tubule . go-plus.json cranial mesonephric tubule http://purl.obolibrary.org/obo/UBERON_0005104 UBERON:0005103 biolink:AnatomicalEntity mesonephric epithelium An epithelium that is part of a mesonephros [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005103 UBERON:0005102 biolink:AnatomicalEntity late distal convoluted tubule The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005102 CHEBI:19591 biolink:ChemicalSubstance 2-hexenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_19591 chebi_ph7_3 NCBITaxon:7746 biolink:OrganismalEntity Petromyzontidae go-plus.json lampreys http://purl.obolibrary.org/obo/NCBITaxon_7746 NCBITaxon:7745 biolink:OrganismalEntity Petromyzontiformes go-plus.json Petromyzoniformes|lampreys http://purl.obolibrary.org/obo/NCBITaxon_7745 CHEBI:68523 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_68523 CHEBI:68525 biolink:ChemicalSubstance (S)-3-amino-3-phenylpropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68525 CHEBI:44510 biolink:ChemicalSubstance (S)-2-hydroxy-4-methylpentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44510 CHEBI:68520 biolink:ChemicalSubstance alkyl,acyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68520 CHEBI:68521 biolink:ChemicalSubstance alkyl,acyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68521 CHEBI:68528 biolink:ChemicalSubstance 3-amino-3-phenylpropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68528 CHEBI:68527 biolink:ChemicalSubstance 3-ammonio-3-phenylpropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68527 chebi_ph7_3 CHEBI:68530 biolink:ChemicalSubstance [beta-D-Galf-(1->5)-beta-D-Galf-(1->6)]14-beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_68530 NCBITaxon:7762 biolink:OrganismalEntity Myxinidae go-plus.json hagfishes http://purl.obolibrary.org/obo/NCBITaxon_7762 NCBITaxon:7761 biolink:OrganismalEntity Myxiniformes go-plus.json Myxinoidea|hagfishes http://purl.obolibrary.org/obo/NCBITaxon_7761 CHEBI:19573 biolink:ChemicalSubstance 2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_19573 CHEBI:68546 biolink:ChemicalSubstance phosphate group(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68546 chebi_ph7_3 UBERON:0005156 biolink:AnatomicalEntity reproductive structure Any anatomical structure that is part of the reproductive system. go-plus.json reproductive system element|reproductive system structure http://purl.obolibrary.org/obo/UBERON_0005156 UBERON:0005155 biolink:AnatomicalEntity open tracheal system An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. go-plus.json open tracheal system|tracheal system|invertebrate tracheal system http://purl.obolibrary.org/obo/UBERON_0005155 UBERON:0005154 biolink:AnatomicalEntity epithelial cord A cord of epithelial cells without a lumen and usually several cells thick. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005154 UBERON:0005153 biolink:AnatomicalEntity epithelial bud A bud is a protrusion that forms from an epithelial sheet by localized folding. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005153 UBERON:0005151 biolink:AnatomicalEntity metanephric proximal tubule The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005151 CHEBI:68549 biolink:ChemicalSubstance diphosphate group(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68549 chebi_ph7_3 UBERON:0005158 biolink:AnatomicalEntity parenchyma of central nervous system The functional tissue of the central nervous system consisting of neurons and glial cells. go-plus.json central nervous system parenchyma|CNS parenchyma|parenchyma of central nervous system|parenchyma of CNS http://purl.obolibrary.org/obo/UBERON_0005158 UBERON:0005157 biolink:AnatomicalEntity epithelial fold An epithelial sheet bent on a linear axis. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005157 GO:0043704 biolink:BiologicalProcess photoreceptor cell fate specification The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0043704 UBERON:0005145 biolink:AnatomicalEntity metanephric comma-shaped body The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005145 GO:0043703 biolink:BiologicalProcess photoreceptor cell fate determination The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0043703 UBERON:0005144 biolink:AnatomicalEntity metanephric glomerular capillary This process pertains to the initial formation of a structure from unspecified parts[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005144 GO:0043706 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043706 GO:0043705 biolink:BiologicalProcess cyanophycin metabolic process The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups. go-plus.json cyanophycin metabolism|multi-L-arginyl-poly(L-aspartic acid) metabolism http://purl.obolibrary.org/obo/GO_0043705 GO:0043700 biolink:CellularComponent pterinosome A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance. go-plus.json http://purl.obolibrary.org/obo/GO_0043700 UBERON:0005141 biolink:AnatomicalEntity metanephric short descending thin limb The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005141 UBERON:0005140 biolink:AnatomicalEntity metanephric short nephron Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005140 CHEBI:19515 biolink:ChemicalSubstance 2-cis,6-trans-farnesyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19515 GO:0043702 biolink:CellularComponent carotenoid vesicle A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance. go-plus.json http://purl.obolibrary.org/obo/GO_0043702 GO:0043701 biolink:CellularComponent cyanosome A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance. go-plus.json http://purl.obolibrary.org/obo/GO_0043701 CHEBI:19511 biolink:ChemicalSubstance 2-cis,6-cis-farnesyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19511 GO:0043708 biolink:BiologicalProcess cell adhesion involved in biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm. go-plus.json cell adhesion during biofilm formation http://purl.obolibrary.org/obo/GO_0043708 UBERON:0005149 biolink:AnatomicalEntity metanephric connecting tubule The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005149 UBERON:0005148 biolink:AnatomicalEntity metanephric S-shaped body The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005148 GO:0043707 biolink:BiologicalProcess cell adhesion involved in single-species biofilm formation in or on host organism The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species. go-plus.json cell adhesion during single-species biofilm formation in or on host organism http://purl.obolibrary.org/obo/GO_0043707 UBERON:0005147 biolink:AnatomicalEntity metanephric renal vesicle The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]. go-plus.json metanephric vesicle http://purl.obolibrary.org/obo/UBERON_0005147 GO:0043709 biolink:BiologicalProcess cell adhesion involved in single-species biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species. go-plus.json cell adhesion during single-species biofilm formation http://purl.obolibrary.org/obo/GO_0043709 UBERON:0005146 biolink:AnatomicalEntity metanephric nephron tubule A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005146 CHEBI:68560 biolink:ChemicalSubstance UDP-N-acetyl-6-(alpha-D-galactose-1-phosphonato)-alpha-D-glucosamine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68560 chebi_ph7_3 CHEBI:68563 biolink:ChemicalSubstance P2Y12 receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_68563 GO:0043715 biolink:MolecularActivity 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P. MetaCyc:R82-RXN|RHEA:18769|EC:5.3.2.5 go-plus.json MasA|DK-MTP-1-P enolase activity|mtnW|E-1 http://purl.obolibrary.org/obo/GO_0043715 UBERON:0005134 biolink:AnatomicalEntity metanephric nephron epithelium The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005134 GO:0043714 biolink:MolecularActivity (R)-citramalate synthase activity Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA. EC:2.3.1.182|MetaCyc:RXN-7743|RHEA:19045 go-plus.json citramalate synthase http://purl.obolibrary.org/obo/GO_0043714 UBERON:0005133 biolink:AnatomicalEntity metanephric glomerulus vasculature The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005133 GO:0043717 biolink:MolecularActivity 2-hydroxyglutaryl-CoA dehydratase activity Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA. RHEA:42448|MetaCyc:RXN-1083 go-plus.json (R)-2-hydroxyglutaryl-CoA dehydratase activity http://purl.obolibrary.org/obo/GO_0043717 UBERON:0005132 biolink:AnatomicalEntity metanephric long nephron Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005132 GO:0043716 biolink:MolecularActivity 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene. MetaCyc:R83-RXN|RHEA:14481|KEGG_REACTION:R07394 go-plus.json 2-hydroxy-3-keto-5-methylthio-phosphopentene phosphatase activity|HK-MTPenyl-1-P phosphatase activity http://purl.obolibrary.org/obo/GO_0043716 UBERON:0005130 biolink:AnatomicalEntity metanephric loop of Henle The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005130 GO:0043711 biolink:BiologicalProcess pilus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. go-plus.json pilus organisation|pilus organization and biogenesis http://purl.obolibrary.org/obo/GO_0043711 gocheck_do_not_annotate GO:0043710 biolink:BiologicalProcess cell adhesion involved in multi-species biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species. go-plus.json cell adhesion during multi-species biofilm formation http://purl.obolibrary.org/obo/GO_0043710 GO:0043713 biolink:MolecularActivity (R)-2-hydroxyisocaproate dehydrogenase activity Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+. go-plus.json http://purl.obolibrary.org/obo/GO_0043713 GO:0043712 biolink:MolecularActivity 2-hydroxyisocaproate CoA-transferase activity Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate. go-plus.json (R)-2-hydroxyisocaproate CoA transferase activity|(R)-2-hydroxyisocaproate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0043712 CHEBI:20502 biolink:ChemicalSubstance 5,10-methylenetetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20502 CHEBI:19543 biolink:ChemicalSubstance 2-dehydro-L-idonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19543 UBERON:0005139 biolink:AnatomicalEntity metanephric long descending thin limb go-plus.json http://purl.obolibrary.org/obo/UBERON_0005139 GO:0043719 biolink:MolecularActivity 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O. MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN|EC:1.14.13.- go-plus.json http://purl.obolibrary.org/obo/GO_0043719 CHEBI:20506 biolink:ChemicalSubstance 5,6,7,8-tetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20506 GO:0043718 biolink:MolecularActivity 2-hydroxymethylglutarate dehydrogenase activity Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH. Wikipedia:2-hydroxymethylglutarate_dehydrogenase|MetaCyc:1.1.1.291-RXN|EC:1.1.1.291|RHEA:15505|KEGG_REACTION:R07985 go-plus.json (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity|HgD http://purl.obolibrary.org/obo/GO_0043718 UBERON:0005137 biolink:AnatomicalEntity metanephric capsule The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005137 UBERON:0005136 biolink:AnatomicalEntity metanephric glomerular endothelium The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005136 UBERON:0005135 biolink:AnatomicalEntity metanephric glomerular epithelium A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005135 GO:0043720 biolink:MolecularActivity 3-keto-5-aminohexanoate cleavage activity Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate. MetaCyc:R125-RXN|RHEA:31555 go-plus.json 3-keto-5-aminohexanoate cleavage enzyme http://purl.obolibrary.org/obo/GO_0043720 CHEBI:68576 biolink:ChemicalSubstance dTDP-6-deoxy-beta-L-talose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68576 chebi_ph7_3 GO:0043726 biolink:MolecularActivity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate. RHEA:25197|MetaCyc:RIBOPHOSPHAT-RXN go-plus.json pyrimidine phosphatase activity http://purl.obolibrary.org/obo/GO_0043726 UBERON:0005123 biolink:AnatomicalEntity metanephric prebend segment The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005123 GO:0043725 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043725 UBERON:0005122 biolink:AnatomicalEntity metanephric macula densa The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005122 UBERON:0005121 biolink:AnatomicalEntity metanephric long descending thin limb bend The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005121 GO:0043728 biolink:MolecularActivity 2-keto-4-methylthiobutyrate aminotransferase activity Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine. EC:4.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0043728 GO:0043727 biolink:MolecularActivity 5-amino-4-imidazole carboxylate lyase activity Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate. EC:4.1.1.21 go-plus.json http://purl.obolibrary.org/obo/GO_0043727 UBERON:0005120 biolink:AnatomicalEntity metanephric late distal convoluted tubule The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005120 GO:0043722 biolink:MolecularActivity 4-hydroxyphenylacetate decarboxylase activity Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2). EC:4.1.1.83|KEGG_REACTION:R07312|MetaCyc:4.1.1.83-RXN|RHEA:22732 go-plus.json 4-hydroxyphenylacetate carboxy-lyase activity|4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)|p-Hpd activity|p-hydroxyphenylacetate decarboxylase activity|4-Hpd activity http://purl.obolibrary.org/obo/GO_0043722 GO:0043721 biolink:MolecularActivity 4-hydroxybutanoyl-CoA dehydratase activity Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O. RHEA:26530|EC:4.2.1.120|MetaCyc:RXN-8890|KEGG_REACTION:R05337 go-plus.json gamma-hydroxybutanoyl-CoA dehydratase activity|gamma-hydroxybutyryl-CoA dehydratase activity|4-hydroxybutanoyl-CoA hydro-lyase|4-hydroxybutyryl-CoA dehydratase activity http://purl.obolibrary.org/obo/GO_0043721 GO:0043724 biolink:MolecularActivity 2-keto-3-deoxygalactonate aldolase activity Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate. go-plus.json KDGal aldolase activity http://purl.obolibrary.org/obo/GO_0043724 GO:0043723 biolink:MolecularActivity 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia. MetaCyc:RXN-10058 go-plus.json 2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity|DRAP deaminase activity http://purl.obolibrary.org/obo/GO_0043723 UBERON:0005129 biolink:AnatomicalEntity metanephric distal tubule The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005129 CHEBI:20515 biolink:ChemicalSubstance 5,6-dioxidoindole-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20515 UBERON:0005127 biolink:AnatomicalEntity metanephric thick ascending limb At the macula densa, the thick ascending limb connects to the distal convoluted tubule[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005127 GO:0043729 biolink:MolecularActivity 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate. go-plus.json http://purl.obolibrary.org/obo/GO_0043729 UBERON:0005126 biolink:AnatomicalEntity metanephric S1 The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005126 UBERON:0005125 biolink:AnatomicalEntity metanephric proximal straight tubule The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005125 UBERON:0005124 biolink:AnatomicalEntity metanephric proximal convoluted tubule The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005124 GO:0004129 biolink:MolecularActivity cytochrome-c oxidase activity Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. MetaCyc:CYTOCHROME-C-OXIDASE-RXN|RHEA:11436|EC:7.1.1.9|Reactome:R-HSA-163214 go-plus.json aa3-type cytochrome c oxidase|cytochrome a3 activity|cytochrome c oxidase activity|cbb3-type cytochrome c oxidase|caa3-type cytochrome c oxidase|complex IV (mitochondrial electron transport) activity|indophenolase|indophenol oxidase|cytochrome aa3 activity|Warburg's respiratory enzyme activity|cytochrome oxidase activity|ba3-type cytochrome c oxidase http://purl.obolibrary.org/obo/GO_0004129 GO:0004128 biolink:MolecularActivity cytochrome-b5 reductase activity, acting on NAD(P)H Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5). MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN|Reactome:R-HSA-6806831|EC:1.6.2.2|RHEA:46680|Reactome:R-HSA-198824 go-plus.json NADH:ferricytochrome-b5 oxidoreductase activity|cytochrome b5 reductase activity|NADH-cytochrome b5 reductase activity|reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity|NADH-cytochrome-b5 reductase activity|NADH-ferricytochrome b5 oxidoreductase activity|dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity|NADH 5alpha-reductase activity http://purl.obolibrary.org/obo/GO_0004128 GO:0004125 biolink:MolecularActivity L-seryl-tRNASec selenium transferase activity Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate. MetaCyc:2.9.1.1-RXN|EC:2.9.1.1|RHEA:22728 go-plus.json L-selenocysteinyl-tRNA(Sel) synthase activity|L-seryl-tRNA(Ser) selenium transferase activity|selenophosphate:L-seryl-tRNASec selenium transferase activity|L-selenocysteinyl-tRNASec synthase activity|cysteinyl-tRNA(Sec)-selenium transferase activity|selenocysteinyl-tRNA(Ser) synthase activity|cysteinyl-tRNASel-selenium transferase activity|cysteinyl-tRNA(Ser) selenium transferase activity|cysteinyl-tRNA(Sel)-selenium transferase activity|cysteinyl-tRNASec-selenium transferase activity|L-selenocysteinyl-tRNA(Sec) synthase activity|selenocysteine synthase activity|L-selenocysteinyl-tRNASel synthase activity http://purl.obolibrary.org/obo/GO_0004125 GO:0004124 biolink:MolecularActivity cysteine synthase activity Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate. MetaCyc:ACSERLY-RXN|RHEA:14829|EC:2.5.1.47 go-plus.json O-acetylserine (thiol)-lyase activity|3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)|OAS sulfhydrylase activity|O-acetylserine sulfhydrylase activity|acetylserine sulfhydrylase activity|O-acetylserine (thiol)-lyase A activity|O-acetyl-L-serine sulfhydrylase activity|O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|cysteine synthetase activity|O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity|O-acetyl-L-serine sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0004124 GO:0004127 biolink:MolecularActivity cytidylate kinase activity Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP. MetaCyc:CMPKI-RXN|EC:2.7.4.14 go-plus.json cytidine monophosphate kinase activity|CTP:CMP phosphotransferase activity|ATP:CMP phosphotransferase activity|pyrimidine nucleoside monophosphate kinase activity|deoxycytidine monophosphokinase activity|UMP-CMP kinase activity|CMP kinase activity|deoxycytidylate kinase activity|dCMP kinase activity|ATP:UMP-CMP phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004127 GO:0004126 biolink:MolecularActivity cytidine deaminase activity Catalysis of the reaction: cytidine + H2O = uridine + NH3. EC:3.5.4.5|RHEA:16069|MetaCyc:CYTIDEAM2-RXN|Reactome:R-HSA-83677|Reactome:R-HSA-73608 go-plus.json cytidine aminohydrolase activity|cytosine nucleoside deaminase activity http://purl.obolibrary.org/obo/GO_0004126 GO:0004121 biolink:MolecularActivity cystathionine beta-lyase activity Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate. RHEA:13965|MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN|EC:4.4.1.8 go-plus.json beta-cystathionase activity|cystine lyase activity|L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)|L-cystathionine L-homocysteine-lyase (deaminating)|cystathionine L-homocysteine-lyase (deaminating)|beta C-S lyase activity http://purl.obolibrary.org/obo/GO_0004121 GO:0004120 biolink:MolecularActivity photoreceptor cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0004120 GO:0004123 biolink:MolecularActivity cystathionine gamma-lyase activity Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+. KEGG_REACTION:R01001|Reactome:R-HSA-1614583|RHEA:14005|EC:4.4.1.1|MetaCyc:CYSTAGLY-RXN go-plus.json homoserine dehydratase activity|gamma-cystathionase activity|homoserine deaminase activity|L-cystathionine cysteine-lyase (deaminating)|L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)|homoserine deaminase-cystathionase activity http://purl.obolibrary.org/obo/GO_0004123 GO:0004122 biolink:MolecularActivity cystathionine beta-synthase activity Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O. EC:4.2.1.22|RHEA:10112|MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN|Reactome:R-HSA-1614524 go-plus.json beta-thionase activity|L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|serine sulfhydrylase activity|methylcysteine synthase activity|L-serine hydro-lyase (adding homocysteine)|serine sulfhydrase activity http://purl.obolibrary.org/obo/GO_0004122 GO:0018769 biolink:MolecularActivity 2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate. UM-BBD_reactionID:r0311 go-plus.json http://purl.obolibrary.org/obo/GO_0018769 CHEBI:138745 biolink:ChemicalSubstance 2-[(9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138745 CHEBI:138744 biolink:ChemicalSubstance 2-[(9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138744 GO:0018766 biolink:MolecularActivity dihydrophloroglucinol hydrolase activity Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate. UM-BBD_reactionID:r0008|MetaCyc:R6-RXN|KEGG_REACTION:R07831 go-plus.json http://purl.obolibrary.org/obo/GO_0018766 GO:0018765 biolink:MolecularActivity 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate. MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN|UM-BBD_reactionID:r0263|RHEA:59220 go-plus.json http://purl.obolibrary.org/obo/GO_0018765 GO:0018768 biolink:MolecularActivity 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate. UM-BBD_reactionID:r0458|EC:3.7.1.13 go-plus.json http://purl.obolibrary.org/obo/GO_0018768 GO:0018767 biolink:MolecularActivity 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate. UM-BBD_reactionID:r0399 go-plus.json http://purl.obolibrary.org/obo/GO_0018767 GO:0018762 biolink:MolecularActivity aliphatic nitrilase activity Catalysis of the reaction: R-CN + H2O = R-COOH + NH3. MetaCyc:3.5.5.7-RXN|UM-BBD_reactionID:r0622|EC:3.5.5.7|RHEA:46188 go-plus.json aliphatic nitrile aminohydrolase activity http://purl.obolibrary.org/obo/GO_0018762 GO:0018761 biolink:MolecularActivity bromoxynil nitrilase activity Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil. UM-BBD_enzymeID:e0357|MetaCyc:3.5.5.6-RXN|KEGG_REACTION:R04349|EC:3.5.5.6|RHEA:22100 go-plus.json 3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity|bromoxynil-specific nitrilase activity http://purl.obolibrary.org/obo/GO_0018761 GO:0018764 biolink:MolecularActivity N-isopropylammelide isopropylaminohydrolase activity Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine. RHEA:23608|UM-BBD_enzymeID:e0086|MetaCyc:R123-RXN|EC:3.5.4.42 go-plus.json AtzC http://purl.obolibrary.org/obo/GO_0018764 GO:0018763 biolink:MolecularActivity hydroxydechloroatrazine ethylaminohydrolase activity Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine. UM-BBD_enzymeID:e0085|MetaCyc:R122-RXN|EC:3.5.4.43|RHEA:23092 go-plus.json AtzB|hydroxyatrazine ethylaminohydrolase activity|4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity|hydroxyatrazine hydrolase activity http://purl.obolibrary.org/obo/GO_0018763 GO:0018760 biolink:MolecularActivity thiocyanate hydrolase activity Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+). MetaCyc:RXN-1761|UM-BBD_reactionID:r0598|EC:3.5.5.8|RHEA:21464|KEGG_REACTION:R05780 go-plus.json thiocyanate aminohydrolase activity http://purl.obolibrary.org/obo/GO_0018760 GO:0004139 biolink:MolecularActivity deoxyribose-phosphate aldolase activity Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. MetaCyc:DEOXYRIBOSE-P-ALD-RXN|RHEA:12821|Reactome:R-HSA-6787321|KEGG_REACTION:R01066|EC:4.1.2.4 go-plus.json phosphodeoxyriboaldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity|2-deoxyribose-5-phosphate aldolase activity|deoxyribose-5-phosphate aldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)|deoxyriboaldolase activity http://purl.obolibrary.org/obo/GO_0004139 GO:0004136 biolink:MolecularActivity deoxyadenosine kinase activity Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+). MetaCyc:DEOXYADENOSINE-KINASE-RXN|EC:2.7.1.76|KEGG_REACTION:R02089|RHEA:23452 go-plus.json purine-deoxyribonucleoside kinase activity|deoxyadenosine kinase (phosphorylating)|ATP:deoxyadenosine 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004136 GO:0004135 biolink:MolecularActivity amylo-alpha-1,6-glucosidase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present. EC:3.2.1.33|Reactome:R-HSA-71593|MetaCyc:3.2.1.33-RXN go-plus.json dextrin 6-alpha-D-glucosidase activity|amylo-1,6-glucosidase activity|glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity|dextrin-1,6-glucosidase activity|amylopectin 1,6-glucosidase activity http://purl.obolibrary.org/obo/GO_0004135 GO:0004138 biolink:MolecularActivity deoxyguanosine kinase activity Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+). KEGG_REACTION:R01967|EC:2.7.1.113|MetaCyc:DEOXYGUANOSINE-KINASE-RXN|RHEA:19201 go-plus.json ATP:deoxyguanosine 5'-phosphotransferase activity|2'-deoxyguanosine kinase activity|NTP-deoxyguanosine 5'-phosphotransferase activity|(dihydroxypropoxymethyl)guanine kinase activity|deoxyguanosine kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0004138 GO:0004137 biolink:MolecularActivity deoxycytidine kinase activity Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP. EC:2.7.1.74|MetaCyc:DEOXYCYTIDINE-KINASE-RXN|RHEA:20061 go-plus.json deoxycytidine kinase (phosphorylating)|arabinofuranosylcytosine kinase activity|Ara-C kinase activity|2'-deoxycytidine kinase activity|deoxycytidine-cytidine kinase activity|NTP:deoxycytidine 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004137 GO:0004132 biolink:MolecularActivity dCMP deaminase activity Catalysis of the reaction: dCMP + H2O = dUMP + NH3. Reactome:R-HSA-73596|RHEA:22924|EC:3.5.4.12|MetaCyc:DCMP-DEAMINASE-RXN go-plus.json deoxycytidine monophosphate deaminase activity|deoxycytidylate deaminase activity|dCMP aminohydrolase activity|deoxycytidine-5'-phosphate deaminase activity|deoxy-CMP-deaminase activity|deoxycytidine-5'-monophosphate aminohydrolase activity|deoxycytidylate aminohydrolase activity http://purl.obolibrary.org/obo/GO_0004132 GO:0004131 biolink:MolecularActivity cytosine deaminase activity Catalysis of the reaction: cytosine + H2O = uracil + NH3. RHEA:20605|MetaCyc:CYTDEAM-RXN|EC:3.5.4.1 go-plus.json cytosine aminohydrolase activity|isocytosine deaminase activity http://purl.obolibrary.org/obo/GO_0004131 GO:0004134 biolink:MolecularActivity 4-alpha-glucanotransferase activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan. MetaCyc:AMYLOMALT-RXN|EC:2.4.1.25|MetaCyc:RXN-9023|Reactome:R-HSA-71552|MetaCyc:RXN-1828 go-plus.json 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity|dextrin transglycosylase activity|disproportionating enzyme activity|dextrin glycosyltransferase activity|oligo-1,4-1,4-glucantransferase activity|amylomaltase activity|debranching enzyme maltodextrin glycosyltransferase activity|D-enzyme activity http://purl.obolibrary.org/obo/GO_0004134 GO:0004133 biolink:MolecularActivity glycogen debranching enzyme activity Catalysis of the cleavage of branch points in branched glycogen polymers. go-plus.json http://purl.obolibrary.org/obo/GO_0004133 goslim_pir GO:0004130 biolink:MolecularActivity cytochrome-c peroxidase activity Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O. MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN|EC:1.11.1.5|RHEA:16581 go-plus.json cytochrome c-551 peroxidase activity|apocytochrome c peroxidase activity|cytochrome c peroxidase activity|cytochrome peroxidase activity|ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity|cytochrome c-H2O oxidoreductase activity|mesocytochrome c peroxidase azide|mesocytochrome c peroxidase cyanate|mesocytochrome c peroxidase cyanide http://purl.obolibrary.org/obo/GO_0004130 GO:0018777 biolink:MolecularActivity 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol). go-plus.json http://purl.obolibrary.org/obo/GO_0018777 GO:0018776 biolink:MolecularActivity trans-chloroacrylic acid dehalogenase activity Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde. UM-BBD_reactionID:r0689 go-plus.json http://purl.obolibrary.org/obo/GO_0018776 CHEBI:173084 biolink:ChemicalSubstance ferroptosis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_173084 GO:0018779 biolink:MolecularActivity obsolete 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity http://purl.obolibrary.org/obo/GO_0018779 GO:0018778 biolink:MolecularActivity DL-2 haloacid dehalogenase activity Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate. MetaCyc:RXN-9150|EC:3.8.1.10|UM-BBD_reactionID:r0382 go-plus.json http://purl.obolibrary.org/obo/GO_0018778 GO:0018773 biolink:MolecularActivity acetylpyruvate hydrolase activity Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate. EC:3.7.1.6|UM-BBD_reactionID:r0095|MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN|RHEA:16097|KEGG_REACTION:R00324 go-plus.json 2,4-dioxopentanoate acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0018773 GO:0018772 biolink:MolecularActivity trioxoheptanoate hydrolase activity Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate. UM-BBD_reactionID:r0094|MetaCyc:R306-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0018772 CHEBI:173085 biolink:ChemicalSubstance ferroptosis inducer go-plus.json http://purl.obolibrary.org/obo/CHEBI_173085 GO:0018775 biolink:MolecularActivity 2-hydroxymuconate-semialdehyde hydrolase activity Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate. EC:3.7.1.9|UM-BBD_enzymeID:e0139|MetaCyc:3.7.1.9-RXN|RHEA:14549 go-plus.json 2-hydroxymuconic semialdehyde hydrolase activity|2-hydroxymuconate-semialdehyde formylhydrolase activity|HOD hydrolase activity|HMSH http://purl.obolibrary.org/obo/GO_0018775 GO:0018774 biolink:MolecularActivity 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate. EC:3.7.1.8|RHEA:17161|UM-BBD_enzymeID:e0033|MetaCyc:3.7.1.8-RXN go-plus.json 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity|HOHPDA hydrolase activity|2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity http://purl.obolibrary.org/obo/GO_0018774 GO:0018771 biolink:MolecularActivity 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate. MetaCyc:MHPCHYDROL-RXN|UM-BBD_reactionID:r0438|RHEA:24789|EC:3.7.1.14 go-plus.json 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity|(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity http://purl.obolibrary.org/obo/GO_0018771 GO:0018770 biolink:MolecularActivity 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+. UM-BBD_reactionID:r0444 go-plus.json http://purl.obolibrary.org/obo/GO_0018770 GO:0004107 biolink:MolecularActivity chorismate synthase activity Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. KEGG_REACTION:R01714|EC:4.2.3.5|RHEA:21020|MetaCyc:CHORISMATE-SYNTHASE-RXN go-plus.json 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)|5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity|5-enolpyruvylshikimate-3-phosphate phospholyase activity http://purl.obolibrary.org/obo/GO_0004107 GO:0004106 biolink:MolecularActivity chorismate mutase activity Catalysis of the reaction: chorismate = prephenate. KEGG_REACTION:R01715|RHEA:13897|MetaCyc:CHORISMATEMUT-RXN|EC:5.4.99.5 go-plus.json hydroxyphenylpyruvate synthase activity|chorismate pyruvatemutase activity http://purl.obolibrary.org/obo/GO_0004106 GO:0004109 biolink:MolecularActivity coproporphyrinogen oxidase activity Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX. Reactome:R-HSA-189421|MetaCyc:RXN0-1461|KEGG_REACTION:R03220|RHEA:18257|EC:1.3.3.3 go-plus.json coproporphyrinogen:oxygen oxidoreductase (decarboxylating)|coprogen oxidase activity|coproporphyrinogenase activity|coproporphyrinogen-III oxidase activity http://purl.obolibrary.org/obo/GO_0004109 GO:0004108 biolink:MolecularActivity citrate (Si)-synthase activity Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group. MetaCyc:CITSYN-RXN|EC:2.3.3.1|Reactome:R-HSA-70975 go-plus.json citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity|citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]|citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)|(R)-citric synthase activity|condensing enzyme activity|citrate oxaloacetate-lyase, CoA-acetylating activity|citrogenase activity|citrate synthase activity|oxaloacetate transacetase activity|citrate condensing enzyme activity|citric-condensing enzyme activity|citric synthase activity|citrate synthetase activity|oxalacetic transacetase activity|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] http://purl.obolibrary.org/obo/GO_0004108 GO:0004103 biolink:MolecularActivity choline kinase activity Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+). RHEA:12837|EC:2.7.1.32|KEGG_REACTION:R01021|Reactome:R-HSA-1483004|MetaCyc:CHOLINE-KINASE-RXN go-plus.json choline phosphokinase activity|choline kinase (phosphorylating)|choline-ethanolamine kinase activity|ATP:choline phosphotransferase activity http://purl.obolibrary.org/obo/GO_0004103 GO:0004102 biolink:MolecularActivity choline O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA. KEGG_REACTION:R01023|Reactome:R-HSA-264622|RHEA:18821|EC:2.3.1.6|MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN go-plus.json choline acetyltransferase activity|CHOACTase activity|choline acetylase activity|acetyl-CoA:choline O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0004102 GO:0004105 biolink:MolecularActivity choline-phosphate cytidylyltransferase activity Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline. EC:2.7.7.15|RHEA:18997|Reactome:R-HSA-1483081|MetaCyc:2.7.7.15-RXN go-plus.json phosphorylcholine transferase activity|CDP-choline pyrophosphorylase activity|cytidine diphosphocholine pyrophosphorylase activity|phosphocholine cytidylyltransferase activity|CDP-choline synthetase activity|CTP:phosphocholine cytidylyltransferase activity|choline phosphate cytidylyltransferase activity|phosphorylcholine:CTP cytidylyltransferase activity|CTP:phosphorylcholine cytidylyltransferase activity|phosphorylcholine cytidylyltransferase activity|CTP:choline-phosphate cytidylyltransferase activity|CTP-phosphocholine cytidylyltransferase activity http://purl.obolibrary.org/obo/GO_0004105 GO:0004104 biolink:MolecularActivity cholinesterase activity Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion. MetaCyc:CHOLINESTERASE-RXN|RHEA:21964|EC:3.1.1.8 go-plus.json choline esterase activity|pseudocholinesterase activity|BtChoEase activity|acylcholine acylhydrolase activity|butyrylcholine esterase activity|butyrylcholinesterase activity|non-specific cholinesterase activity|choline esterase II (unspecific) activity|benzoylcholinesterase activity|anticholineesterase activity|propionylcholinesterase activity http://purl.obolibrary.org/obo/GO_0004104 goslim_chembl GO:0004101 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004101 GO:0004100 biolink:MolecularActivity chitin synthase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1). RHEA:16637|MetaCyc:CHITIN-SYNTHASE-RXN|EC:2.4.1.16 go-plus.json chitin-UDP acetyl-glucosaminyl transferase activity|UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity|trans-N-acetylglucosaminosylase activity|chitin-uridine diphosphate acetylglucosaminyltransferase activity|chitin synthetase activity|chitin-UDP N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0004100 GO:0018748 biolink:MolecularActivity iprodione amidohydrolase activity Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate. UM-BBD_reactionID:r0706 go-plus.json http://purl.obolibrary.org/obo/GO_0018748 CHEBI:138724 biolink:ChemicalSubstance all-trans-retinyl heptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138724 chebi_ph7_3 GO:0018747 biolink:MolecularActivity phenanthrene-1,2-epoxide hydrolase activity Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene. UM-BBD_reactionID:r0536 go-plus.json http://purl.obolibrary.org/obo/GO_0018747 CHEBI:138723 biolink:ChemicalSubstance 1-oleoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138723 chebi_ph7_3 CHEBI:138722 biolink:ChemicalSubstance 13-cis-retinyl hexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138722 chebi_ph7_3 GO:0018749 biolink:MolecularActivity (3,5-dichlorophenylurea)acetate amidohydrolase activity Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine. UM-BBD_reactionID:r0708 go-plus.json http://purl.obolibrary.org/obo/GO_0018749 CHEBI:138721 biolink:ChemicalSubstance tetradecyl tetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138721 chebi_ph7_3 GO:0018744 biolink:MolecularActivity limonene-1,2-epoxide hydrolase activity Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide. UM-BBD_reactionID:r0734|RHEA:10700|MetaCyc:3.3.2.8-RXN|EC:3.3.2.8 go-plus.json limonene oxide hydrolase activity http://purl.obolibrary.org/obo/GO_0018744 GO:0018743 biolink:MolecularActivity phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene. EC:3.3.2.-|UM-BBD_reactionID:r0560 go-plus.json http://purl.obolibrary.org/obo/GO_0018743 GO:0018746 biolink:MolecularActivity phenanthrene-3,4-epoxide hydrolase activity Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene. UM-BBD_reactionID:r0535 go-plus.json http://purl.obolibrary.org/obo/GO_0018746 CHEBI:138726 biolink:ChemicalSubstance 3'-unsubstituted flavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_138726 chebi_ph7_3 GO:0018745 biolink:MolecularActivity epoxide hydrolase A activity Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol. EC:3.3.2.-|UM-BBD_enzymeID:e0049 go-plus.json http://purl.obolibrary.org/obo/GO_0018745 GO:0018740 biolink:MolecularActivity 2'-hydroxybiphenyl-2-sulfinate desulfinase activity Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite. MetaCyc:RXN-624|EC:3.13.1.3|UM-BBD_enzymeID:e0216|RHEA:12945|KEGG_REACTION:R07311 go-plus.json DszB|2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity|gene dszB-encoded hydrolase activity|HBPSi desulfinase activity|2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity|2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity|dibenzothiophene desulfurization enzyme B|2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity|2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity|2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity|HPBS desulfinase activity|2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity|2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity http://purl.obolibrary.org/obo/GO_0018740 GO:0018742 biolink:MolecularActivity epoxide hydrolase B activity Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers. EC:3.3.2.-|UM-BBD_enzymeID:e0051 go-plus.json http://purl.obolibrary.org/obo/GO_0018742 GO:0018741 biolink:MolecularActivity alkyl sulfatase activity Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol. EC:3.1.6.-|UM-BBD_reactionID:r0602 go-plus.json alkyl sulphatase activity http://purl.obolibrary.org/obo/GO_0018741 GO:0004118 biolink:MolecularActivity cGMP-stimulated cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP. go-plus.json http://purl.obolibrary.org/obo/GO_0004118 GO:0004117 biolink:MolecularActivity calmodulin-dependent cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin. Reactome:R-HSA-111955 go-plus.json http://purl.obolibrary.org/obo/GO_0004117 GO:0004119 biolink:MolecularActivity cGMP-inhibited cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP. go-plus.json http://purl.obolibrary.org/obo/GO_0004119 GO:0004114 biolink:MolecularActivity 3',5'-cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. EC:3.1.4.17|RHEA:14653|MetaCyc:3.1.4.17-RXN|Reactome:R-HSA-162425 go-plus.json 3',5' cyclic-nucleotide phosphodiesterase activity|nucleoside-3',5-monophosphate phosphodiesterase activity|3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity|3',5'-nucleotide phosphodiesterase activity|cyclic AMP phosphodiesterase activity|cyclic 3',5-nucleotide monophosphate phosphodiesterase activity|cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity|cyclic 3',5'-phosphodiesterase activity|cyclic nucleotide phosphodiesterase activity|cyclic 3',5'-nucleotide phosphodiesterase activity|nucleoside 3',5'-cyclic phosphate diesterase activity|3',5'-cyclonucleotide phosphodiesterase activity|cyclic 3',5'-mononucleotide phosphodiesterase activity|PDE|3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity|3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity|3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity http://purl.obolibrary.org/obo/GO_0004114 GO:0004113 biolink:MolecularActivity 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate. EC:3.1.4.37|RHEA:14489|MetaCyc:3.1.4.37-RXN go-plus.json cyclic-CMP phosphodiesterase activity|2',3'-cyclic nucleotide 3'-phosphohydrolase activity|2',3'-cyclic nucleotide 3'-phosphodiesterase activity|cyclic 2',3'-nucleotide 3'-phosphodiesterase activity|2',3'-cyclic nucleotide phosphohydrolase|CNPase activity|cyclic 2',3'-nucleotide phosphodiesterase|nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity|2',3'-cyclic AMP phosphodiesterase activity|2':3'-cyclic nucleotide 3'-phosphodiesterase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2':3'-CNMP-3'-ase activity http://purl.obolibrary.org/obo/GO_0004113 GO:0004116 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004116 CHEBI:100147 biolink:ChemicalSubstance nalidixic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_100147 GO:0004115 biolink:MolecularActivity 3',5'-cyclic-AMP phosphodiesterase activity Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate. Reactome:R-HSA-9644869|Reactome:R-HSA-9705507|Reactome:R-HSA-9629675|MetaCyc:RXN0-5038|Reactome:R-HSA-111962|EC:3.1.4.53|RHEA:25277|Reactome:R-HSA-418553 go-plus.json 3',5'-cyclic-AMP-specific phosphodiesterase activity|3',5'-cAMP-specific phosphodiesterase activity|adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity|cAMP-specific phosphodiesterase activity|cyclic AMP-specific phosphodiesterase activity|3',5' cAMP-specific phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0004115 GO:0004110 biolink:MolecularActivity corticosteroid side-chain-isomerase activity Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al. MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN|EC:5.3.1.21|KEGG_REACTION:R04165|RHEA:17861 go-plus.json 11-deoxycorticosterone aldose-ketose-isomerase activity|11-deoxycorticosterone ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0004110 GO:0004112 biolink:MolecularActivity cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0004112 GO:0004111 biolink:MolecularActivity creatine kinase activity Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). Reactome:R-HSA-200326|KEGG_REACTION:R01881|Reactome:R-HSA-200318|EC:2.7.3.2|RHEA:17157|MetaCyc:CREATINE-KINASE-RXN go-plus.json MiMi-CK|CK-MB|creatine phosphokinase activity|Mi-CK|creatine phosphotransferase activity|ATP:creatine N-phosphotransferase activity|ATP:creatine phosphotransferase activity|BB-CK|MM-CK|adenosine triphosphate-creatine transphosphorylase activity|CK|CK-BB|CK-MM|CKMiMi|MB-CK|phosphocreatine kinase activity http://purl.obolibrary.org/obo/GO_0004111 GO:0102700 biolink:MolecularActivity alpha-thujene synthase activity Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid. MetaCyc:RXN-5105 go-plus.json http://purl.obolibrary.org/obo/GO_0102700 GO:0102702 biolink:MolecularActivity 2-carene synthase activity Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid. MetaCyc:RXN-5122 go-plus.json http://purl.obolibrary.org/obo/GO_0102702 GO:0102701 biolink:MolecularActivity tricyclene synthase activity Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid. MetaCyc:RXN-5121|RHEA:32687|EC:4.2.3.105 go-plus.json http://purl.obolibrary.org/obo/GO_0102701 GO:0018759 biolink:MolecularActivity methenyltetrahydromethanopterin cyclohydrolase activity Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+). UM-BBD_reactionID:r0347|EC:3.5.4.27|KEGG_REACTION:R03464|MetaCyc:3.5.4.27-RXN|RHEA:19053 go-plus.json 5,10-methenyltetrahydromethanopterin cyclohydrolase activity|N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity|methenyl-H4MPT cyclohydrolase activity|methenyl-H(4)MPT cyclohydrolase activity|5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing) http://purl.obolibrary.org/obo/GO_0018759 GO:0102704 biolink:MolecularActivity GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol. EC:2.4.1.257|MetaCyc:RXN-5463|RHEA:29519 go-plus.json http://purl.obolibrary.org/obo/GO_0102704 CHEBI:138735 biolink:ChemicalSubstance 1-[(9Z)-octadecenyl]-2,3-dioleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138735 chebi_ph7_3 GO:0102703 biolink:MolecularActivity camphene synthase activity Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid. RHEA:25484|MetaCyc:RXN-5142|EC:4.2.3.117 go-plus.json http://purl.obolibrary.org/obo/GO_0102703 GO:0018758 biolink:MolecularActivity 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid. UM-BBD_reactionID:r0122 go-plus.json http://purl.obolibrary.org/obo/GO_0018758 CHEBI:138734 biolink:ChemicalSubstance 1-[(9Z)-octadecenyl]monooleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138734 chebi_ph7_3 GO:0102706 biolink:MolecularActivity butein:oxygen oxidoreductase activity Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+. EC:1.21.3.6|MetaCyc:RXN-6242|RHEA:34203 go-plus.json http://purl.obolibrary.org/obo/GO_0102706 CHEBI:138733 biolink:ChemicalSubstance alpha-D-galactosyl ditrans,octacis-undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138733 chebi_ph7_3 GO:0102705 biolink:MolecularActivity serine decarboxylase activity Catalysis of the reaction: H+ + L-serine <=> ethanolaminium(1+) + carbon dioxide. MetaCyc:RXN-5641|RHEA:45824 go-plus.json http://purl.obolibrary.org/obo/GO_0102705 CHEBI:138732 biolink:ChemicalSubstance 3',5'-dimethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_138732 chebi_ph7_3 GO:0102708 biolink:MolecularActivity S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine. MetaCyc:RXN-6462 go-plus.json http://purl.obolibrary.org/obo/GO_0102708 GO:0018755 biolink:MolecularActivity 2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-. go-plus.json http://purl.obolibrary.org/obo/GO_0018755 GO:0018754 biolink:MolecularActivity ammelide aminohydrolase activity Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3. MetaCyc:RXN-8017 go-plus.json http://purl.obolibrary.org/obo/GO_0018754 GO:0102707 biolink:MolecularActivity S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine. EC:2.1.1.49|MetaCyc:RXN-6461 go-plus.json http://purl.obolibrary.org/obo/GO_0102707 GO:0018757 biolink:MolecularActivity deisopropylhydroxyatrazine aminohydrolase activity Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine. UM-BBD_reactionID:r0121|KEGG_REACTION:R05574 go-plus.json http://purl.obolibrary.org/obo/GO_0018757 GO:0102709 biolink:MolecularActivity S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine. MetaCyc:RXN-6464 go-plus.json http://purl.obolibrary.org/obo/GO_0102709 GO:0018756 biolink:MolecularActivity ammeline aminohydrolase activity Catalysis of the reaction: ammeline + H2O = ammelide + NH3. RHEA:26201|MetaCyc:RXN-8016 go-plus.json http://purl.obolibrary.org/obo/GO_0018756 CHEBI:6923 biolink:ChemicalSubstance miconazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_6923 GO:0018751 biolink:MolecularActivity 3,5-dichlorophenylcarboximide hydrolase activity Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate. UM-BBD_reactionID:r0707 go-plus.json http://purl.obolibrary.org/obo/GO_0018751 GO:0018750 biolink:MolecularActivity biuret amidohydrolase activity Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3. RHEA:17525|EC:3.5.1.84|UM-BBD_reactionID:r0846 go-plus.json http://purl.obolibrary.org/obo/GO_0018750 GO:0018753 biolink:MolecularActivity cyanuric acid amidohydrolase activity Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2. MetaCyc:R468-RXN|EC:3.5.2.15|RHEA:14641|UM-BBD_reactionID:r0116 go-plus.json http://purl.obolibrary.org/obo/GO_0018753 GO:0018752 biolink:MolecularActivity epsilon-caprolactam lactamase activity Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate. MetaCyc:R561-RXN|UM-BBD_reactionID:r0448 go-plus.json http://purl.obolibrary.org/obo/GO_0018752 CHEBI:138731 biolink:ChemicalSubstance 5'-hydroxy-3'-methoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_138731 chebi_ph7_3 CHEBI:138730 biolink:ChemicalSubstance 3'-methoxyflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_138730 chebi_ph7_3 CHEBI:44576 biolink:ChemicalSubstance 2'-hydroxybiphenyl-2-sulfinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44576 GO:0018729 biolink:MolecularActivity propionate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA. RHEA:23520|EC:2.8.3.1|MetaCyc:PROPIONATE-COA-TRANSFERASE-RXN|UM-BBD_reactionID:r0087 go-plus.json propionyl CoA:acetate CoA transferase activity|acetyl-CoA:propanoate CoA-transferase activity|propionate coenzyme A-transferase activity|propionate-CoA:lactoyl-CoA transferase activity|propionyl-CoA transferase activity http://purl.obolibrary.org/obo/GO_0018729 GO:0018726 biolink:MolecularActivity 9-phenanthrol sulfotransferase activity Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate. UM-BBD_reactionID:r0564 go-plus.json 9-phenanthrol sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018726 GO:0018725 biolink:MolecularActivity trans-3,4-dihydrodiolphenanthrene sulfotransferase activity Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate. UM-BBD_reactionID:r0558 go-plus.json trans-3,4-dihydrodiolphenanthrene sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018725 GO:0018728 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018728 GO:0018727 biolink:MolecularActivity 2-phenanthrol sulfotransferase activity Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate. UM-BBD_reactionID:r0563 go-plus.json 2-phenanthrol sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018727 NCBITaxon:90371 biolink:OrganismalEntity Salmonella enterica subsp. enterica serovar Typhimurium go-plus.json Salmonella choleraesuis serotype typhimurium|Salmonella enterica subsp. enterica serovar 1,4,[5],12,:i:1,2|Salmonella typhi-murium|Salmonella typhimurium|Salmonella enterica ser. typhimurium|Salmonella enterica serotype Typhimurium|Bacillus typhimurium|Salmonella enterica 1,4,[5],12,:i:1,2|Salmonella enterica serovar Typhimurium http://purl.obolibrary.org/obo/NCBITaxon_90371 GO:0018722 biolink:MolecularActivity 1-phenanthrol sulfotransferase activity Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate. UM-BBD_reactionID:r0565 go-plus.json 1-phenanthrol sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018722 GO:0018721 biolink:MolecularActivity trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate. UM-BBD_reactionID:r0559 go-plus.json trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018721 GO:0018724 biolink:MolecularActivity 4-phenanthrol sulfotransferase activity Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate. UM-BBD_reactionID:r0562 go-plus.json 4-phenanthrol sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018724 CHEBI:138704 biolink:ChemicalSubstance 13-cis-retinyl tetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138704 chebi_ph7_3 GO:0018723 biolink:MolecularActivity 3-phenanthrol sulfotransferase activity Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate. UM-BBD_reactionID:r0561 go-plus.json 3-phenanthrol sulphotransferase activity http://purl.obolibrary.org/obo/GO_0018723 GO:0018720 biolink:MolecularActivity phenol kinase activity Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate. UM-BBD_reactionID:r0155|MetaCyc:PHENOLPHOS-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0018720 CHEBI:138718 biolink:ChemicalSubstance all-trans-retinyl tetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138718 chebi_ph7_3 GO:0018737 biolink:MolecularActivity 2-ketocyclohexane-1-carboxyl-CoA hydrolase activity Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA. UM-BBD_reactionID:r0193 go-plus.json http://purl.obolibrary.org/obo/GO_0018737 GO:0018736 biolink:MolecularActivity 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA. UM-BBD_reactionID:r0206 go-plus.json http://purl.obolibrary.org/obo/GO_0018736 GO:0018739 biolink:MolecularActivity 4-hydroxybenzoyl-CoA thioesterase activity Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+). RHEA:11948|EC:3.1.2.23|KEGG_REACTION:R01301|UM-BBD_reactionID:r0141|MetaCyc:3.1.2.23-RXN go-plus.json 4-hydroxybenzoyl-CoA hydrolase activity|4-hydroxybenzoyl-CoA thiolesterase activity http://purl.obolibrary.org/obo/GO_0018739 GO:0018738 biolink:MolecularActivity S-formylglutathione hydrolase activity Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+). KEGG_REACTION:R00527|EC:3.1.2.12|MetaCyc:S-FORMYLGLUTATHIONE-HYDROLASE-RXN|UM-BBD_reactionID:r0241|RHEA:14961|Reactome:R-HSA-5693724 go-plus.json http://purl.obolibrary.org/obo/GO_0018738 goslim_chembl GO:0018733 biolink:MolecularActivity 3,4-dihydrocoumarin hydrolase activity Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate. EC:3.1.1.35|UM-BBD_reactionID:r0419 go-plus.json http://purl.obolibrary.org/obo/GO_0018733 GO:0018732 biolink:MolecularActivity sulfolactone hydrolase activity Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate. UM-BBD_reactionID:r0583|EC:3.1.1.92 go-plus.json sulpholactone hydrolase activity http://purl.obolibrary.org/obo/GO_0018732 GO:0018735 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018735 GO:0018734 biolink:MolecularActivity butyrolactone hydrolase activity Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate. UM-BBD_reactionID:r0016 go-plus.json http://purl.obolibrary.org/obo/GO_0018734 GO:0018731 biolink:MolecularActivity 1-oxa-2-oxocycloheptane lactonase activity Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate. UM-BBD_reactionID:r0167 go-plus.json http://purl.obolibrary.org/obo/GO_0018731 GO:0018730 biolink:MolecularActivity glutaconate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA. RHEA:23208|EC:2.8.3.12|UM-BBD_reactionID:r0085|MetaCyc:GLUTACONATE-COA-TRANSFERASE-RXN go-plus.json acetyl-CoA:(E)-glutaconate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0018730 CHEBI:44557 biolink:ChemicalSubstance nitrilotriacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44557 GO:0018708 biolink:MolecularActivity thiol S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether. EC:2.1.1.9|RHEA:18277|MetaCyc:THIOL-S-METHYLTRANSFERASE-RXN|Reactome:R-HSA-175976|UM-BBD_enzymeID:e0146 go-plus.json TMT|thiol methyltransferase activity|S-adenosyl-L-methionine:thiol S-methyltransferase activity http://purl.obolibrary.org/obo/GO_0018708 GO:0018707 biolink:MolecularActivity 1-phenanthrol methyltransferase activity Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene. UM-BBD_reactionID:r0493 go-plus.json http://purl.obolibrary.org/obo/GO_0018707 CHEBI:741548 biolink:ChemicalSubstance ethylmalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_741548 GO:0018709 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018709 GO:0018704 biolink:MolecularActivity obsolete 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity OBSOLETE. Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde. go-plus.json 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity http://purl.obolibrary.org/obo/GO_0018704 GO:0018703 biolink:MolecularActivity 2,4-dichlorophenoxyacetate dehalogenase activity Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate. UM-BBD_reactionID:r0280 go-plus.json http://purl.obolibrary.org/obo/GO_0018703 GO:0018706 biolink:MolecularActivity pyrogallol hydroxytransferase activity Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene. RHEA:21000|EC:1.97.1.2|UM-BBD_reactionID:r0006|MetaCyc:1.97.1.2-RXN go-plus.json 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity|1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity|pyrogallol hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity|1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)|transhydroxylase activity http://purl.obolibrary.org/obo/GO_0018706 GO:0018705 biolink:MolecularActivity 1,2-dichloroethene reductive dehalogenase activity Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride. UM-BBD_enzymeID:e0272 go-plus.json 1,2-dichloroethylene reductive dehalogenase activity http://purl.obolibrary.org/obo/GO_0018705 GO:0018700 biolink:MolecularActivity 2-chloro-N-isopropylacetanilide reductive dehalogenase activity Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide. UM-BBD_reactionID:r0719|EC:1.97.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018700 GO:0018702 biolink:MolecularActivity 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU. EC:1.97.1.-|UM-BBD_reactionID:r0440 go-plus.json 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity|DDE dehalogenase activity http://purl.obolibrary.org/obo/GO_0018702 GO:0018701 biolink:MolecularActivity 2,5-dichlorohydroquinone reductive dehalogenase activity Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone). EC:1.97.1.-|UM-BBD_enzymeID:e0366 go-plus.json http://purl.obolibrary.org/obo/GO_0018701 GO:0018719 biolink:MolecularActivity 6-aminohexanoate transaminase activity Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate. UM-BBD_reactionID:r0449|MetaCyc:R562-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0018719 GO:0018718 biolink:MolecularActivity 1,2-dihydroxy-phenanthrene glycosyltransferase activity Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP. UM-BBD_reactionID:r0569 go-plus.json http://purl.obolibrary.org/obo/GO_0018718 GO:0018715 biolink:MolecularActivity 9-phenanthrol UDP-glucuronosyltransferase activity Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP. UM-BBD_reactionID:r0567 go-plus.json http://purl.obolibrary.org/obo/GO_0018715 GO:0018714 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018714 GO:0018717 biolink:MolecularActivity 9-phenanthrol glycosyltransferase activity Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O. UM-BBD_reactionID:r0511 go-plus.json http://purl.obolibrary.org/obo/GO_0018717 GO:0018716 biolink:MolecularActivity 1-phenanthrol glycosyltransferase activity Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O. UM-BBD_reactionID:r0525 go-plus.json http://purl.obolibrary.org/obo/GO_0018716 GO:0018711 biolink:MolecularActivity benzoyl acetate-CoA thiolase activity Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA. UM-BBD_reactionID:r0243|MetaCyc:RXN-1305 go-plus.json http://purl.obolibrary.org/obo/GO_0018711 GO:0018710 biolink:MolecularActivity acetone carboxylase activity Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate. MetaCyc:6.4.1.6-RXN|KEGG_REACTION:R05735|EC:6.4.1.6|RHEA:18385 go-plus.json acetone:carbon-dioxide ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0018710 CHEBI:44549 biolink:ChemicalSubstance 4-amino-5-aminomethyl-2-methylpyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44549 GO:0018713 biolink:MolecularActivity 3-ketopimelyl-CoA thiolase activity Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA. MetaCyc:RXN-8032|UM-BBD_reactionID:r0197 go-plus.json http://purl.obolibrary.org/obo/GO_0018713 GO:0018712 biolink:MolecularActivity 3-hydroxybutyryl-CoA thiolase activity Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA. MetaCyc:R7-RXN|UM-BBD_reactionID:r0010 go-plus.json http://purl.obolibrary.org/obo/GO_0018712 GO:0102511 biolink:MolecularActivity pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+. EC:2.4.1.300|MetaCyc:RXN-14440 go-plus.json http://purl.obolibrary.org/obo/GO_0102511 GO:0102510 biolink:MolecularActivity pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+. EC:2.4.1.299|MetaCyc:RXN-14439 go-plus.json http://purl.obolibrary.org/obo/GO_0102510 GO:0102513 biolink:MolecularActivity delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+. MetaCyc:RXN-14442 go-plus.json http://purl.obolibrary.org/obo/GO_0102513 GO:0102512 biolink:MolecularActivity delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+. EC:2.4.1.299|MetaCyc:RXN-14441 go-plus.json http://purl.obolibrary.org/obo/GO_0102512 GO:0102515 biolink:MolecularActivity pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+. MetaCyc:RXN-14447 go-plus.json http://purl.obolibrary.org/obo/GO_0102515 GO:0102514 biolink:MolecularActivity cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+. EC:2.4.1.300|MetaCyc:RXN-14446 go-plus.json http://purl.obolibrary.org/obo/GO_0102514 PO:0030056 biolink:OntologyClass archesporial cell A native plant cell (PO:0025606) that divides to gives rise to a sporocyte (PO:0006204) and is part of a sporangium (PO:0025094). go-plus.json sporogenous cell (exact)|胞原細胞 (Japanese, exact)|archesporial initial (exact)|célula arquesporial (Spanish, exact) http://purl.obolibrary.org/obo/PO_0030056 GO:0102517 biolink:MolecularActivity oleate 12-hydroxylase activity Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O. MetaCyc:RXN-14487 go-plus.json http://purl.obolibrary.org/obo/GO_0102517 GO:0102516 biolink:MolecularActivity delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+. MetaCyc:RXN-14448 go-plus.json http://purl.obolibrary.org/obo/GO_0102516 GO:0102518 biolink:MolecularActivity (11Z)-eicosenoate 14-hydroxylase activity Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O. EC:1.14.18.4|MetaCyc:RXN-14488 go-plus.json http://purl.obolibrary.org/obo/GO_0102518 GO:0102520 biolink:MolecularActivity L-threonine O-3-phosphate phosphatase activity Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine + hydrogenphosphate. MetaCyc:RXN-14505 go-plus.json http://purl.obolibrary.org/obo/GO_0102520 GO:0102522 biolink:MolecularActivity tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe. RHEA:36355|EC:2.5.1.114|MetaCyc:RXN-14518 go-plus.json http://purl.obolibrary.org/obo/GO_0102522 GO:0102521 biolink:MolecularActivity tRNA-4-demethylwyosine synthase activity Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe. EC:4.1.3.44|RHEA:36347|MetaCyc:RXN-14516 go-plus.json http://purl.obolibrary.org/obo/GO_0102521 GO:0102524 biolink:MolecularActivity tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe. EC:1.14.11.42|RHEA:37899|MetaCyc:RXN-14538 go-plus.json http://purl.obolibrary.org/obo/GO_0102524 GO:0102523 biolink:MolecularActivity 2-chloroacrylate reductase activity Catalysis of the reaction: (S)-2-chloropropanoate + NADP <=> 2-chloroacrylate + NADPH + H+. EC:1.3.1.103|RHEA:36591|MetaCyc:RXN-14536 go-plus.json http://purl.obolibrary.org/obo/GO_0102523 GO:0102526 biolink:MolecularActivity 8-demethylnovobiocic acid C8-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine + novobiocic acid + H+. EC:2.1.1.284|MetaCyc:RXN-14543|RHEA:36651 go-plus.json http://purl.obolibrary.org/obo/GO_0102526 GO:0102525 biolink:MolecularActivity 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide. MetaCyc:RXN-14542|EC:1.14.11.41|RHEA:36607 go-plus.json http://purl.obolibrary.org/obo/GO_0102525 GO:0102528 biolink:MolecularActivity 7,8,4'-trihydroxyflavone methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone. MetaCyc:RXN-14658 go-plus.json http://purl.obolibrary.org/obo/GO_0102528 GO:0102527 biolink:MolecularActivity 8-demethylnovobiocate synthase activity Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid. EC:6.3.1.15|RHEA:36699|MetaCyc:RXN-14547 go-plus.json http://purl.obolibrary.org/obo/GO_0102527 GO:0102529 biolink:MolecularActivity apigenin 7-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + apigenin-7-olate <=> S-adenosyl-L-homocysteine + genkwanin. MetaCyc:RXN-14661 go-plus.json http://purl.obolibrary.org/obo/GO_0102529 PO:0030073 biolink:OntologyClass exothecium A portion of epidermis (PO:0005679) that is the outermost layer of a sporangium wall (PO:0025306). go-plus.json epithecium (exact)|sporangium wall exothecium (exact)|sporangium epidermis (exact)|葯の表皮（外膜) (Japanese, exact)|exotecio (Spanish, exact) http://purl.obolibrary.org/obo/PO_0030073 NCBITaxon:2812636 biolink:OrganismalEntity CS clade go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2812636 GO:0102531 biolink:MolecularActivity ecdysteroid-phosphate phosphatase activity Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = hydrogenphosphate + an ecdysteroid. MetaCyc:RXN-14734|RHEA:63576 go-plus.json http://purl.obolibrary.org/obo/GO_0102531 GO:0102530 biolink:MolecularActivity aclacinomycin T methylesterase activity Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T + methanol + H+. RHEA:37891|MetaCyc:RXN-14703|EC:3.1.1.95 go-plus.json http://purl.obolibrary.org/obo/GO_0102530 GO:0102533 biolink:MolecularActivity genkwanin 4'-O-methyltransferase activity Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine. MetaCyc:RXN-14750 go-plus.json http://purl.obolibrary.org/obo/GO_0102533 GO:0102532 biolink:MolecularActivity genkwanin 6-hydroxylase activity Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP. MetaCyc:RXN-14748 go-plus.json http://purl.obolibrary.org/obo/GO_0102532 GO:0102535 biolink:MolecularActivity ladanein 6-O-methyltransferase activity Catalysis of the reaction: ladanein + S-adenosyl-L-methionine <=> H+ + salvigenin + S-adenosyl-L-homocysteine. MetaCyc:RXN-14752 go-plus.json http://purl.obolibrary.org/obo/GO_0102535 GO:0102534 biolink:MolecularActivity apigenin-7,4'-dimethyl ether 6-hydroxylase activity Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP. MetaCyc:RXN-14751 go-plus.json http://purl.obolibrary.org/obo/GO_0102534 GO:0102537 biolink:MolecularActivity ecdysone-phosphate phosphatase activity Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate. MetaCyc:RXN-14766 go-plus.json http://purl.obolibrary.org/obo/GO_0102537 GO:0102536 biolink:MolecularActivity sakuranetin 6-hydroxylase activity Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP. MetaCyc:RXN-14754 go-plus.json http://purl.obolibrary.org/obo/GO_0102536 GO:0102539 biolink:MolecularActivity UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H. MetaCyc:RXN-14769 go-plus.json http://purl.obolibrary.org/obo/GO_0102539 GO:0102538 biolink:MolecularActivity UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H. MetaCyc:RXN-14767 go-plus.json http://purl.obolibrary.org/obo/GO_0102538 CHEBI:6750 biolink:ChemicalSubstance (+)-menthofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_6750 chebi_ph7_3 GO:0102540 biolink:MolecularActivity D-mannose 6-phosphate 1-epimerase activity Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate. MetaCyc:RXN-14815 go-plus.json http://purl.obolibrary.org/obo/GO_0102540 GO:0102542 biolink:MolecularActivity aclacinomycin A methylesterase activity Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+. EC:3.1.1.95|MetaCyc:RXN-14863 go-plus.json http://purl.obolibrary.org/obo/GO_0102542 GO:0102541 biolink:MolecularActivity D-galactose 6-phosphate 1-epimerase activity Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate. MetaCyc:RXN-14816 go-plus.json http://purl.obolibrary.org/obo/GO_0102541 GO:0102544 biolink:MolecularActivity ornaline synthase activity Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP + H2O. MetaCyc:RXN-14880 go-plus.json http://purl.obolibrary.org/obo/GO_0102544 GO:0102543 biolink:MolecularActivity epsilon-rhodomycinone methylesterase activity Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+. EC:3.1.1.95|MetaCyc:RXN-14865 go-plus.json http://purl.obolibrary.org/obo/GO_0102543 GO:0102546 biolink:MolecularActivity mannosylglycerate hydrolase activity Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate. RHEA:58456|MetaCyc:RXN-14900 go-plus.json http://purl.obolibrary.org/obo/GO_0102546 GO:0102545 biolink:MolecularActivity phosphatidyl phospholipase B activity Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate. EC:3.1.1.5|MetaCyc:RXN-14899 go-plus.json http://purl.obolibrary.org/obo/GO_0102545 GO:0102547 biolink:MolecularActivity glucosylglycerate hydrolase activity Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate. RHEA:32059|MetaCyc:RXN-14901 go-plus.json http://purl.obolibrary.org/obo/GO_0102547 GO:0102549 biolink:MolecularActivity 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+. EC:3.1.1.26|MetaCyc:RXN-14912 go-plus.json http://purl.obolibrary.org/obo/GO_0102549 GO:0004289 biolink:MolecularActivity obsolete subtilase activity OBSOLETE. Was not defined before being made obsolete. go-plus.json subtilase activity http://purl.obolibrary.org/obo/GO_0004289 GO:0004286 biolink:MolecularActivity obsolete proprotein convertase 2 activity OBSOLETE. Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond. go-plus.json NEC 2 activity|PC2 activity|proprotein convertase 2 activity|neuroendocrine convertase 2 activity|prohormone convertase II activity http://purl.obolibrary.org/obo/GO_0004286 GO:0004285 biolink:MolecularActivity obsolete proprotein convertase 1 activity OBSOLETE. Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond. go-plus.json NEC 1 activity|prohormone convertase 3|PC1 activity|proprotein convertase 1 activity|neuroendocrine convertase 1 activity|prohormone convertase I activity http://purl.obolibrary.org/obo/GO_0004285 GO:0004287 biolink:MolecularActivity obsolete prolyl oligopeptidase activity OBSOLETE. Catalysis of the hydrolysis of Pro-Xaa > Ala-Xaa in oligopeptides. go-plus.json prolyl oligopeptidase activity|endoprolylpeptidase activity|prolyl endopeptidase activity|post-proline endopeptidase activity|post-proline cleaving enzyme activity|proline-specific endopeptidase activity|proline endopeptidase activity http://purl.obolibrary.org/obo/GO_0004287 GO:0004281 biolink:MolecularActivity obsolete pancreatic elastase II activity OBSOLETE. Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin. go-plus.json pancreatic elastase II activity|pancreatic elastase 2 http://purl.obolibrary.org/obo/GO_0004281 GO:0004284 biolink:MolecularActivity obsolete acrosin activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa. go-plus.json acrosomal proteinase activity|beta-acrosin|acrosin activity|acrosomal protease activity|acrozonase activity|psi-acrosin|alpha-acrosin|acrosin amidase activity http://purl.obolibrary.org/obo/GO_0004284 GO:0004283 biolink:MolecularActivity obsolete plasmin activity OBSOLETE. Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products. go-plus.json fibrinolysin activity|fibrinase activity|serum tryptase activity|plasmin activity|actase activity|thrombolysin http://purl.obolibrary.org/obo/GO_0004283 GO:0004291 biolink:MolecularActivity obsolete subtilisin activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides. go-plus.json savinase 8.0L|savinase 32.0 L EX|protin A 3L|colistinase activity|protease XXVII|savinase 16.0L|subtilisin GX|esperase activity|subtilisin E|subtilisin sendai|savinase activity|thermoase|subtilopeptidase activity|protease S|subtilisin BL|alcalase 0.6L|alcalase 2.5L|genenase I|bioprase AL 15|alcalase activity|bacillus subtilis alkaline proteinase bioprase activity|protease VIII|kazusase activity|thermoase PC 10|savinase 4.0T|bacillopeptidase B|superase activity|bioprase APL 30|bacillopeptidase A|subtilisin S41|bacillus subtilis alkaline proteinase activity|opticlean|maxatase activity|orientase 10B|subtilisin J|subtilisin DY|SP 266|ALK-enzyme|subtilisin activity http://purl.obolibrary.org/obo/GO_0004291 GO:0004290 biolink:MolecularActivity obsolete kexin activity OBSOLETE. Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors. go-plus.json Kex2-like precursor protein processing endoprotease|andrenorphin-Gly-generating enzyme|proteinase yscF activity|proteinase Kex2p|Kex2 protease|paired-basic endopeptidase activity|Kex2 endopeptidase|prohormone-processing proteinase activity|Kex2 proteinase|yeast KEX2 protease activity|endoproteinase Kex2p|protease KEX2|Kex2 endoprotease|Kex2-like endoproteinase|Kex2 endoproteinase|Kex 2p proteinase|yeast cysteine proteinase F|gene KEX2 dibasic proteinase|kexin activity|prohormone-processing KEX2 proteinase|prohormone-processing endoprotease activity http://purl.obolibrary.org/obo/GO_0004290 GO:0004297 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004297 GO:0004296 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004296 GO:0004299 biolink:MolecularActivity obsolete proteasome endopeptidase activity OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity. go-plus.json multicatalytic endopeptidase|proteasome|proteasome endopeptidase complex|proteasome endopeptidase activity http://purl.obolibrary.org/obo/GO_0004299 GO:0004298 biolink:MolecularActivity threonine-type endopeptidase activity Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile. EC:3.4.25.- go-plus.json threonine endopeptidase activity|ingensin|tricorn protease|tricorn proteinase|26S protease|prosome|alkaline protease|multicatalytic proteinase (complex)|large multicatalytic protease|multicatalytic proteinase|proteasome endopeptidase complex|MCP|multicatalytic endopeptidase complex|lens neutral proteinase http://purl.obolibrary.org/obo/GO_0004298 GO:0004293 biolink:MolecularActivity obsolete tissue kallikrein activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds. go-plus.json submaxillary kallikrein|pancreatic kallikrein|urinary kallikrein|tissue kallikrein activity|glumorin|submandibular kallikrein|onokrein P|urokallikrein|padreatin|depot-padutin|bradykininogenase|dilminal D|glandular kallikrein activity|padutin|kininogenase|kallidinogenase|kininogenin activity|kidney kallikrein|salivary kallikrein|callicrein http://purl.obolibrary.org/obo/GO_0004293 GO:0004295 biolink:MolecularActivity obsolete trypsin activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa. go-plus.json tripcellim|alpha-trypsin activity|pseudotrypsin|parenzyme|sperm receptor hydrolase activity|parenzymol|trypure|beta-trypsin activity|cocoonase activity|trypsin activity|tryptar http://purl.obolibrary.org/obo/GO_0004295 GO:0004294 biolink:MolecularActivity obsolete tripeptidyl-peptidase II activity OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH. go-plus.json TPP|tripeptidyl aminopeptidase II|tripeptidyl peptidase II|tripeptidyl-peptidase II activity|tripeptidyl aminopeptidase activity|tripeptidyl peptidase activity http://purl.obolibrary.org/obo/GO_0004294 NCBITaxon:1489872 biolink:OrganismalEntity Percomorphaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1489872 CHEBI:138792 biolink:ChemicalSubstance 1,2-di-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138792 GO:0004263 biolink:MolecularActivity obsolete chymotrypsin activity OBSOLETE. Catalysis of the preferential cleavage of Tyr-Xaa > Trp-Xaa > Phe-Xaa > Leu-Xaa. go-plus.json avazyme|quimotrase activity|chymotrypsins A and B|alpha-chymotrypsin activity|alpha-chymotrypsin A|quimar|alpha-chymar|enzeon|alpha-chymar ophth|chymotrypsin A activity|chymar|chymotrypsin B activity|chymotest|chymotrypsin activity http://purl.obolibrary.org/obo/GO_0004263 GO:0004262 biolink:MolecularActivity obsolete cerevisin activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides. go-plus.json yeast proteinase B activity|baker's yeast proteinase B|peptidase beta|proteinase yscB activity|brewer's yeast proteinase|cerevisin activity http://purl.obolibrary.org/obo/GO_0004262 GO:0004261 biolink:MolecularActivity obsolete cathepsin G activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to chymotrypsin C. go-plus.json chymotrypsin-like proteinase activity|cathepsin G activity|neutral proteinase activity http://purl.obolibrary.org/obo/GO_0004261 GO:0004279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004279 GO:0004278 biolink:MolecularActivity obsolete granzyme B activity OBSOLETE. Catalysis of the preferential cleavage of Asp-Xaa > Asn-Xaa > Met-Xaa, Ser-Xaa. go-plus.json CCPII|CTLA1|cytotoxic t-lymphocyte proteinase 2 activity|granzyme B activity|CCP1 proteinase|cytotoxic cell proteinase-1|granzyme H|granzyme G http://purl.obolibrary.org/obo/GO_0004278 GO:0004275 biolink:MolecularActivity obsolete enteropeptidase activity OBSOLETE. Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen. go-plus.json enteropeptidase activity|enterokinase activity http://purl.obolibrary.org/obo/GO_0004275 GO:0004274 biolink:MolecularActivity obsolete dipeptidyl-peptidase IV activity OBSOLETE. Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline. EC:3.4.14.5|MetaCyc:3.4.14.5-RXN go-plus.json lymphocyte antigen CD26|X-PDAP|postproline dipeptidyl aminopeptidase IV|dipeptidyl aminopeptidase IV activity|glycylprolyl dipeptidylaminopeptidase activity|pep X|amino acyl-prolyl dipeptidyl aminopeptidase activity|leukocyte antigen CD26|dipeptidyl-peptidase IV activity|glycylproline aminopeptidase activity|Xaa-Pro-dipeptidylaminopeptidase activity|post-proline dipeptidyl aminopeptidase IV activity|dipeptidyl-aminopeptidase IV|DPP IV/CD26|glycoprotein GP110|dipeptidyl-peptide hydrolase activity|DPP IV activity|dipeptidyl peptidase IV|glycylprolyl aminopeptidase activity|Xaa-Pro-dipeptidyl-aminopeptidase activity|T cell triggering molecule Tp103|Gly-Pro naphthylamidase activity http://purl.obolibrary.org/obo/GO_0004274 GO:0004277 biolink:MolecularActivity obsolete granzyme A activity OBSOLETE. Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates. go-plus.json T-cell derived serine proteinase|CTLA3|HuTPS|cytotoxic T-lymphocyte proteinase 1 activity|granzyme A activity|cytotoxic T lymphocyte serine protease|T-cell associated protease 1|TSP-1 http://purl.obolibrary.org/obo/GO_0004277 GO:0102500 biolink:MolecularActivity beta-maltose 4-alpha-glucanotransferase activity Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose. MetaCyc:RXN-14354|EC:2.4.1.25 go-plus.json http://purl.obolibrary.org/obo/GO_0102500 GO:0004276 biolink:MolecularActivity obsolete furin activity OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors. go-plus.json PACE|SPC3|furin activity|paired basic amino acid converting enzyme|prohormone convertase activity|paired basic amino acid cleaving enzyme|serine proteinase PACE|paired basic amino acid residue cleaving enzyme activity|dibasic processing enzyme activity http://purl.obolibrary.org/obo/GO_0004276 GO:0102502 biolink:MolecularActivity ADP-glucose-starch glucosyltransferase activity Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose. MetaCyc:RXN-14378|EC:2.4.1.242 go-plus.json http://purl.obolibrary.org/obo/GO_0102502 GO:0102501 biolink:MolecularActivity D-fructuronate reductase activity Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate. MetaCyc:RXN-14368 go-plus.json http://purl.obolibrary.org/obo/GO_0102501 GO:0102504 biolink:MolecularActivity luteolinidin 5-O-glucosyltransferase activity Catalysis of the reaction: luteolinidin + UDP-alpha-D-glucose <=> luteolinidin 5-O-glucoside + UDP + 2 H+. MetaCyc:RXN-14424 go-plus.json http://purl.obolibrary.org/obo/GO_0102504 GO:0102506 biolink:MolecularActivity cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+. MetaCyc:RXN-14432|EC:2.4.1.299 go-plus.json http://purl.obolibrary.org/obo/GO_0102506 GO:0102505 biolink:MolecularActivity apigeninidin 5-O-glucosyltransferase activity Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+. MetaCyc:RXN-14427 go-plus.json http://purl.obolibrary.org/obo/GO_0102505 GO:0004280 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004280 GO:0102508 biolink:MolecularActivity cyanidin 3,7-diglucoside glucosidase activity Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose. MetaCyc:RXN-14435 go-plus.json http://purl.obolibrary.org/obo/GO_0102508 GO:0102507 biolink:MolecularActivity cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + 4-hydroxybenzoic acid + H+. MetaCyc:RXN-14434|EC:2.4.1.300 go-plus.json http://purl.obolibrary.org/obo/GO_0102507 GO:0102509 biolink:MolecularActivity cyanidin 3,5-diglucoside glucosidase activity Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose. MetaCyc:RXN-14436 go-plus.json http://purl.obolibrary.org/obo/GO_0102509 GO:0102591 biolink:MolecularActivity delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose. MetaCyc:RXN-15352 go-plus.json http://purl.obolibrary.org/obo/GO_0102591 GO:0102590 biolink:MolecularActivity delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+. MetaCyc:RXN-15351 go-plus.json http://purl.obolibrary.org/obo/GO_0102590 GO:0102593 biolink:MolecularActivity UDP-glucose: N-methylanthranilate glucosyltransferase activity Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP. MetaCyc:RXN-15371 go-plus.json http://purl.obolibrary.org/obo/GO_0102593 GO:0102592 biolink:MolecularActivity delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose. MetaCyc:RXN-15354 go-plus.json http://purl.obolibrary.org/obo/GO_0102592 GO:0102595 biolink:MolecularActivity cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(6-O-(p-hydroxybenzoyl)-glucosyl)-oxybenzoyl)-glucoside) + beta-D-glucose. MetaCyc:RXN-15374 go-plus.json http://purl.obolibrary.org/obo/GO_0102595 GO:0102594 biolink:MolecularActivity cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose. MetaCyc:RXN-15372 go-plus.json http://purl.obolibrary.org/obo/GO_0102594 GO:0043850 biolink:CellularComponent RecFOR complex A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0043850 UBERON:0005192 biolink:AnatomicalEntity deferent duct artery An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]. go-plus.json arteria ductus deferentis|artery of ductus deferens|vas deferens artery|ductus deferens artery http://purl.obolibrary.org/obo/UBERON_0005192 GO:0102597 biolink:MolecularActivity 3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O. EC:1.14.14.122|RHEA:41468|MetaCyc:RXN-15381 go-plus.json http://purl.obolibrary.org/obo/GO_0102597 GO:0102596 biolink:MolecularActivity cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O. MetaCyc:RXN-15379|EC:1.14.14.70|RHEA:41464 go-plus.json http://purl.obolibrary.org/obo/GO_0102596 GO:0043852 biolink:MolecularActivity monomethylamine methyltransferase activity Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3. RHEA:26059|EC:2.1.1.248|MetaCyc:RXN-8098 go-plus.json MMAMT|MtmB|monomethylamine:corrinoid methyltransferase activity http://purl.obolibrary.org/obo/GO_0043852 GO:0102599 biolink:MolecularActivity cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-beta-amyrin + H2O + NAD(P). MetaCyc:RXN-15383 go-plus.json http://purl.obolibrary.org/obo/GO_0102599 GO:0043851 biolink:MolecularActivity methanol-specific methylcobalamin:coenzyme M methyltransferase activity Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M. MetaCyc:RXN-8096 go-plus.json methanol-specific methylcobalamin: coenzyme M methyltransferase activity|methanol-specific methylcobalamin:CoM methyltransferase activity|MtaA|MT2|MtaC protein:coenzyme M methyltransferase activity|MtaC protein: coenzyme M methyltransferase activity|methyltransferase 2 http://purl.obolibrary.org/obo/GO_0043851 GO:0102598 biolink:MolecularActivity 3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O. EC:1.14.14.123|MetaCyc:RXN-15382|RHEA:41472 go-plus.json http://purl.obolibrary.org/obo/GO_0102598 CHEBI:68465 biolink:ChemicalSubstance 2,6-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68465 CHEBI:68464 biolink:ChemicalSubstance 4-(3-methylbut-2-enyl)-L-abrine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68464 GO:0043858 biolink:MolecularActivity arginine:ornithine antiporter activity Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out). go-plus.json ArcD|arginine-ornithine antiporter activity|arginine/ornithine antiporter activity http://purl.obolibrary.org/obo/GO_0043858 GO:0043857 biolink:MolecularActivity N-acetylornithine carbamoyltransferase activity Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate. EC:2.1.3.9|KEGG_REACTION:R07245|RHEA:18609|MetaCyc:2.1.3.9-RXN go-plus.json carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity|N-acetylornithine transcarbamylase activity|acetylornithine transcarbamylase activity|AOTC|carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity http://purl.obolibrary.org/obo/GO_0043857 UBERON:0005199 biolink:AnatomicalEntity cervical mammary gland A mammary gland that is part of a cervical region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005199 GO:0043859 biolink:MolecularActivity obsolete cyanophycinase activity OBSOLETE. Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. go-plus.json cyanophycinase activity http://purl.obolibrary.org/obo/GO_0043859 GO:0043854 biolink:MolecularActivity cyclic nucleotide-gated mechanosensitive ion channel activity Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts. go-plus.json cyclic nucleotide-regulated small mechanosensitive ion channel|cyclic nucleotide regulated mechanosensitive ion channel|cyclic nucleotide gated mechanosensitive ion channel activity|small conductance mechanosensitive ion channel|cyclic nucleotide-regulated mechanosensitive ion channel|MscS http://purl.obolibrary.org/obo/GO_0043854 UBERON:0005196 biolink:AnatomicalEntity spleen germinal center A germinal center that is part of the spleen. The spleen germinal center is located in a secondary B follicle in the white pulp of the spleen. go-plus.json splenic germinal center|spleen GC|spleen follicle center|germinal center of spleen http://purl.obolibrary.org/obo/UBERON_0005196 GO:0043853 biolink:CellularComponent methanol-CoM methyltransferase complex A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol. MetaCyc:CPLX-421 go-plus.json methanol-coenzyme M methyltransferase complex|methanol: CoM methyltransferase complex|methanol:coenzyme M methyltransferase complex|methanol:CoM methyltransferase complex|methanol: coenzyme M methyltransferase complex http://purl.obolibrary.org/obo/GO_0043853 UBERON:0005195 biolink:AnatomicalEntity deferent duct vein A vein that is part of a vas deferens [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005195 GO:0043856 biolink:MolecularActivity anti-sigma factor antagonist activity The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity. go-plus.json anti-anti-sigma factor activity http://purl.obolibrary.org/obo/GO_0043856 UBERON:0005194 biolink:AnatomicalEntity thoracic vein A vein that is part of a thorax [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005194 GO:0043855 biolink:MolecularActivity cyclic nucleotide-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts. go-plus.json cyclic nucleotide-activated ion channel activity|cyclic nucleotide activated ion channel activity|cyclic nucleotide gated ion channel activity http://purl.obolibrary.org/obo/GO_0043855 PO:0005022 biolink:OntologyClass plant ovary wall A portion of plant tissue (PO:0009007) that is composed of plant ovary outer epidermis (PO:0005023), plant ovary inner epidermis (PO:0005024), and a plant ovary wall middle layer (PO:0005025) go-plus.json pared del ovario (Spanish, exact)|子房壁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0005022 CHEBI:68472 biolink:ChemicalSubstance pyrimidine deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_68472 CHEBI:68471 biolink:ChemicalSubstance (Z)-2,3-dehydroadipoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_68471 UBERON:0005181 biolink:AnatomicalEntity thoracic segment organ An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. go-plus.json upper body organ http://purl.obolibrary.org/obo/UBERON_0005181 GO:0043861 biolink:MolecularActivity agmatine:putrescine antiporter activity Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out). go-plus.json agmatine/putrescine antiporter activity|agmatine-putrescine antiporter activity http://purl.obolibrary.org/obo/GO_0043861 GO:0043860 biolink:MolecularActivity cyanophycin synthetase activity Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer). EC:6.3.1.- go-plus.json cphA http://purl.obolibrary.org/obo/GO_0043860 GO:0043863 biolink:MolecularActivity 4-hydroxy-2-ketopimelate aldolase activity Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate. MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN|RHEA:25788 go-plus.json HHED aldolase activity|HpaI|HpcH|2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity http://purl.obolibrary.org/obo/GO_0043863 GO:0043862 biolink:MolecularActivity arginine:agmatine antiporter activity Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out). go-plus.json AdiC|arginine/agmatine antiporter activity|arginine-agmatine antiporter activity|arginine-agmatine exchange transporter activity http://purl.obolibrary.org/obo/GO_0043862 GO:0043869 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043869 GO:0043868 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043868 GO:0043865 biolink:MolecularActivity methionine transmembrane transporter activity Enables the transfer of methionine from one side of a membrane to the other. go-plus.json methionine importing activity|methionine importer|methionine importer activity|methionine-importing activity http://purl.obolibrary.org/obo/GO_0043865 UBERON:0005185 biolink:AnatomicalEntity renal medulla collecting duct The portion of the collecting duct that resides in the renal medulla go-plus.json kidney medulla collecting duct|medullary collecting duct http://purl.obolibrary.org/obo/UBERON_0005185 GO:0043864 biolink:MolecularActivity indoleacetamide hydrolase activity Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA. MetaCyc:G-5841|EC:3.5.1.4|RHEA:34371 go-plus.json IaaH|Tms2|IAH|indole-3-acetamide hydrolase activity|indole acetamide hydrolase activity http://purl.obolibrary.org/obo/GO_0043864 UBERON:0005184 biolink:AnatomicalEntity hair medulla Innermost layer of the hair shaft. go-plus.json medulla of hair shaft http://purl.obolibrary.org/obo/UBERON_0005184 GO:0043867 biolink:MolecularActivity 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine. go-plus.json TgtA|archaeal tRNA-guanine transglycosylase activity|archaeosine tRNA-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0043867 GO:0043866 biolink:MolecularActivity adenylyl-sulfate reductase (thioredoxin) activity Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin. RHEA:21976|EC:1.8.4.10 go-plus.json AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)|AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)|thioredoxin-dependent 5'-adenylylsulfate reductase activity http://purl.obolibrary.org/obo/GO_0043866 PO:0005011 biolink:OntologyClass anther dehiscence zone A dehiscence zone (PO:0025092) that is part of an anther (PO:0009066). go-plus.json zona de dehiscencia de la antera (Spanish, exact)|開葯帯 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0005011 PO:0005010 biolink:OntologyClass anther septum A septum (PO:0000030) that is part of an anther dehiscence zone (PO:0005011). go-plus.json septo de la antera (Spanish, exact)|anther dissepiment (broad)|葯隔壁 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0005010 CHEBI:68483 biolink:ChemicalSubstance UDP-N-acetyl-3-O-(1-carboxylatovinyl)-alpha-D-glucosamine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68483 chebi_ph7_3 CHEBI:68485 biolink:ChemicalSubstance alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_68485 chebi_ph7_3 CHEBI:68481 biolink:ChemicalSubstance mTOR inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_68481 GO:0043872 biolink:MolecularActivity lysine:cadaverine antiporter activity Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out). go-plus.json cadaverine:lysine antiporter activity|lysine/cadaverine antiporter activity|cadaverine transmembrane transporter activity|lysine-cadaverine antiporter activity http://purl.obolibrary.org/obo/GO_0043872 UBERON:0005170 biolink:AnatomicalEntity granulosa cell layer A layer of the ovarian follicle that consists of granulosa cells. go-plus.json membrana granulosa|ovary stratum granulosum|granulosa cell layer of ovarian follicle|granulosa cell layers|membrana granulosa of ovarian follicle|granulosa cell layer|stratum granulosum of ovarian follicle http://purl.obolibrary.org/obo/UBERON_0005170 GO:0043871 biolink:MolecularActivity delta1-piperideine-6-carboxylate dehydrogenase activity Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate. RHEA:49476|MetaCyc:RXN-8162 go-plus.json PIPOX|AmaB http://purl.obolibrary.org/obo/GO_0043871 GO:0043874 biolink:MolecularActivity acireductone synthase activity Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. MetaCyc:3.1.3.77-RXN|Reactome:R-HSA-1237129|RHEA:21700|EC:3.1.3.77 go-plus.json E-1|5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)|E-1 enolase-phosphatase http://purl.obolibrary.org/obo/GO_0043874 GO:0043873 biolink:MolecularActivity pyruvate-flavodoxin oxidoreductase activity Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. RHEA:44140|MetaCyc:PYFLAVOXRE-RXN go-plus.json NifJ|pyruvate:flavodoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0043873 CHEBI:68487 biolink:ChemicalSubstance strigolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_68487 GO:0043870 biolink:MolecularActivity N-acetyl-gamma-aminoadipyl-phosphate reductase activity Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH. RHEA:41948|MetaCyc:RXN-5183 go-plus.json N-acetyl-aminoadipate semialdehyde dehydrogenase activity|N-acetyl-alpha-glutamyl-phosphate reductase activity|AGPR|NAGSA dehydrogenase activity|LysY|ArgC http://purl.obolibrary.org/obo/GO_0043870 CHEBI:68489 biolink:ChemicalSubstance alkyl,acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68489 chebi_ph7_3 CHEBI:68488 biolink:ChemicalSubstance alkyl,acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_68488 chebi_ph7_3 UBERON:0005178 biolink:AnatomicalEntity thoracic cavity element An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. go-plus.json thoracic cavity organ http://purl.obolibrary.org/obo/UBERON_0005178 GO:0043879 biolink:MolecularActivity glycolate transmembrane transporter activity Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA). RHEA:29447 go-plus.json glycolic acid transmembrane transporter activity|glcA|hydroxyacetic acid transmembrane transporter activity|glycolate permease http://purl.obolibrary.org/obo/GO_0043879 UBERON:0005177 biolink:AnatomicalEntity trunk region element An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. go-plus.json trunk organ http://purl.obolibrary.org/obo/UBERON_0005177 UBERON:0005176 biolink:AnatomicalEntity tooth enamel organ A circumscribed mass of ectodermal cells which bud off from the dental lamina; it becomes cup-shaped and develops on its internal face the ameloblast layer of cells that produces the enamel cap of a developing tooth. go-plus.json enamel organ|odontogenic organ|organum enameleum|dental organ http://purl.obolibrary.org/obo/UBERON_0005176 UBERON:0005175 biolink:AnatomicalEntity chest organ An organ that is part of a chest [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005175 GO:0043876 biolink:MolecularActivity D-threonine aldolase activity Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde. RHEA:15257|MetaCyc:4.1.2.42-RXN|EC:4.1.2.42 go-plus.json D-allo-TA|DtaAS|D-TA|D-allo-threonine aldolase activity|low-specificity D-threonine aldolase http://purl.obolibrary.org/obo/GO_0043876 UBERON:0005174 biolink:AnatomicalEntity dorsal region element An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. go-plus.json dorsal region organ|back organ http://purl.obolibrary.org/obo/UBERON_0005174 GO:0043875 biolink:MolecularActivity 2-ketobutyrate formate-lyase activity Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate. MetaCyc:KETOBUTFORMLY-RXN go-plus.json keto-acid formate acetyltransferase|KFL|TdcE http://purl.obolibrary.org/obo/GO_0043875 UBERON:0005173 biolink:AnatomicalEntity abdominal segment element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. go-plus.json abdominal segment organ http://purl.obolibrary.org/obo/UBERON_0005173 CHEBI:19504 biolink:ChemicalSubstance 2-chloro-cis,cis-muconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_19504 chebi_ph7_3 GO:0043878 biolink:MolecularActivity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+. RHEA:25294|EC:1.2.1.3|MetaCyc:RXN-3443 go-plus.json glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity|non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)|NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NAD) activity http://purl.obolibrary.org/obo/GO_0043878 UBERON:0005172 biolink:AnatomicalEntity abdomen element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. go-plus.json abdomen organ http://purl.obolibrary.org/obo/UBERON_0005172 GO:0043877 biolink:MolecularActivity galactosamine-6-phosphate isomerase activity Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3. go-plus.json AgaI|galactosamine-6-phosphate deaminase activity http://purl.obolibrary.org/obo/GO_0043877 CHEBI:19503 biolink:ChemicalSubstance propachlor go-plus.json http://purl.obolibrary.org/obo/CHEBI_19503 chebi_ph7_3 UBERON:0005171 biolink:AnatomicalEntity hepatic duct Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion). go-plus.json http://purl.obolibrary.org/obo/UBERON_0005171 UBERON:5101466 biolink:AnatomicalEntity pedal digit digitopodial skeleton A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit plus the associated metapodial element. go-plus.json pedal digit skeleton|pedal digit http://purl.obolibrary.org/obo/UBERON_5101466 UBERON:0005179 biolink:AnatomicalEntity pelvic region element An organ or element that is part of the pelvic region. Examples: reproductive organs (in some organisms), urinary bladder, bones of the pelvis. go-plus.json pelvic element|pelvis region organ|pelvis organ http://purl.obolibrary.org/obo/UBERON_0005179 CHEBI:68494 biolink:ChemicalSubstance apoptosis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_68494 CHEBI:68493 biolink:ChemicalSubstance dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68493 chebi_ph7_3 CHEBI:68495 biolink:ChemicalSubstance apoptosis inducer go-plus.json http://purl.obolibrary.org/obo/CHEBI_68495 CHEBI:68490 biolink:ChemicalSubstance alkyl,acyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68490 chebi_ph7_3 CHEBI:68492 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-alpha-D-galactose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68492 chebi_ph7_3 GO:0043883 biolink:MolecularActivity malolactic enzyme activity Catalysis of the reaction: malate + H+ = L-lactate + CO2. go-plus.json MleS http://purl.obolibrary.org/obo/GO_0043883 GO:0043882 biolink:MolecularActivity malate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in). go-plus.json malate-sodium symporter activity|malate Na(+) symporter activity|malate/sodium symporter activity|malate/sodium cotransporter activity|sodium/malate symporter activity|Na(+)-malate symporter activity|malate:Na+ symporter activity|malate:sodium cotransporter activity|sodium:malate symporter activity|Na+:malate symporter activity|sodium-dependent malate transporter http://purl.obolibrary.org/obo/GO_0043882 GO:0043885 biolink:MolecularActivity carbon-monoxide dehydrogenase (ferredoxin) activity Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin. EC:1.2.7.4|MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN go-plus.json carbon-monoxide:(acceptor) oxidoreductase activity|carbon monoxide dehydrogenase (ferredoxin) activity|CO dehydrogenase activity|CODH|CO-dehydrogenase (ferredoxin) activity|carbon monoxide dehydrogenase activity|carbon-monoxide dehydrogenase activity|carbon-monoxide,water:ferredoxin oxidoreductase activity|CO-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0043885 GO:0043884 biolink:MolecularActivity CO-methylating acetyl-CoA synthase activity Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA. MetaCyc:ACETYLSYNCLTH-RXN|RHEA:45212|EC:2.3.1.169 go-plus.json CO-methylating acetyl-coenzyme A synthase activity|acetyl-CoA:corrinoid protein O-acetyltransferase activity|ACS|acetyl-CoA synthase activity http://purl.obolibrary.org/obo/GO_0043884 CHEBI:68498 biolink:ChemicalSubstance lysophosphatidyl-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68498 chebi_ph7_3 CHEBI:68497 biolink:ChemicalSubstance lysophosphatidylserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68497 chebi_ph7_3 GO:0043881 biolink:MolecularActivity mesaconyl-CoA hydratase activity Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA. go-plus.json mch|mesaconyl-coenzyme A hydratase activity|beta-methylmalyl-CoA dehydratase activity http://purl.obolibrary.org/obo/GO_0043881 GO:0043880 biolink:MolecularActivity crotonyl-CoA reductase activity Catalysis of the reduction of crotonyl-CoA to butyryl-CoA. go-plus.json CCR|crotonyl-coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_0043880 NCBITaxon:55879 biolink:OrganismalEntity Rhabditoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_55879 UBERON:0005164 biolink:AnatomicalEntity ascending limb of loop of Henle The distal part of the loop of Henle that is impermeable to water and actively pumps sodium out of the filtrate to generate the hypertonic interstitium that drives countercurrent exchange; it consists of an initial very thin segment lined by simple squamous epithelium followed by a distal thick segment lined by simple cuboidal epithelium[MP]. go-plus.json distal straight tubule|loop of Henle ascending limb|ascending limb of Henle's loop|ascending limb http://purl.obolibrary.org/obo/UBERON_0005164 GO:0043887 biolink:MolecularActivity melibiose:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in). go-plus.json Na+:melibiose symporter activity|melibiose:Na+ symporter activity|melibiose/sodium symporter activity|sodium:melibiose symporter activity|melibiose permease|melibiose/Na+ symporter activity|Na+/melibiose symporter activity|sodium/melibiose symporter activity|melibiose-Na+ symporter activity|thiomethylgalactoside permease II|Na+-melibiose symporter activity|sodium-melibiose symporter activity|Na+ (Li+)/melibiose symporter activity|MelB|melibiose carrier protein|melibiose-sodium symporter activity http://purl.obolibrary.org/obo/GO_0043887 UBERON:0005162 biolink:AnatomicalEntity multi cell part structure A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. go-plus.json cell part cluster|multi-cell-part structure|multi-cell-component structure http://purl.obolibrary.org/obo/UBERON_0005162 GO:0043886 biolink:MolecularActivity structural constituent of carboxysome The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO(2). go-plus.json http://purl.obolibrary.org/obo/GO_0043886 GO:0043889 biolink:MolecularActivity (S)-3-O-geranylgeranylglyceryl phosphate synthase activity Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate. go-plus.json (S)-GGGP synthase activity|GGGPS|GGGP synthase activity|(S)-3-O-geranylgeranylglycerylphosphate synthase activity http://purl.obolibrary.org/obo/GO_0043889 GO:0043888 biolink:MolecularActivity (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate. EC:2.5.1.- go-plus.json DGGGPS|DGGGP synthase activity|UbiA|2,3-dGGGPS http://purl.obolibrary.org/obo/GO_0043888 UBERON:0005169 biolink:AnatomicalEntity interstitial tissue connective tissue between the cellular elements of a structure. go-plus.json interstitium http://purl.obolibrary.org/obo/UBERON_0005169 GO:0102551 biolink:MolecularActivity homogentisate geranylgeranyl transferase activity Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide. EC:2.5.1.116|RHEA:38003|MetaCyc:RXN-14929 go-plus.json http://purl.obolibrary.org/obo/GO_0102551 GO:0102550 biolink:MolecularActivity 2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+. EC:2.1.1.295|RHEA:38007|MetaCyc:RXN-14917 go-plus.json http://purl.obolibrary.org/obo/GO_0102550 GO:0102553 biolink:MolecularActivity lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein) Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. MetaCyc:RXN-14957|EC:2.8.1.8 go-plus.json http://purl.obolibrary.org/obo/GO_0102553 GO:0043894 biolink:MolecularActivity acetyl-CoA synthetase acetyltransferase activity Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate. go-plus.json Pat|Pat enzyme|protein acetyltransferase activity http://purl.obolibrary.org/obo/GO_0043894 GO:0102552 biolink:MolecularActivity lipoyl synthase activity (acting on glycine-cleavage complex H protein Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. MetaCyc:RXN-14950|EC:2.8.1.8 go-plus.json http://purl.obolibrary.org/obo/GO_0102552 GO:0043893 biolink:MolecularActivity acetate:cation symporter activity Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in). go-plus.json cation:acetate symporter activity|acetate-cation symporter activity|acetate/cation symporter activity|ActP|cation/acetate symporter activity|cation-acetate symporter activity|acetate permease http://purl.obolibrary.org/obo/GO_0043893 GO:0043896 biolink:MolecularActivity glucan 1,6-alpha-glucosidase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides. MetaCyc:3.2.1.70-RXN|EC:3.2.1.70 go-plus.json exo-1,6-alpha-glucosidase activity|exo-1,6-beta-glucosidase|glucan-1,6-alpha-glucosidase activity|glucan alpha-1,6-D-glucohydrolase activity|glucodextrinase|glucodextranase activity http://purl.obolibrary.org/obo/GO_0043896 GO:0102555 biolink:MolecularActivity octanoyl transferase activity (acting on glycine-cleavage complex H protein) Catalysis of the reaction: [glycine cleavage system lipoyl-carrier protein]-L-lysine + octanoyl-ACP = H+ + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein]. MetaCyc:RXN-14966|EC:2.3.1.181|RHEA:17665 go-plus.json http://purl.obolibrary.org/obo/GO_0102555 GO:0102554 biolink:MolecularActivity lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. MetaCyc:RXN-14959 go-plus.json http://purl.obolibrary.org/obo/GO_0102554 GO:0043895 biolink:MolecularActivity cyclomaltodextrin glucanotransferase activity Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond. EC:2.4.1.19|MetaCyc:2.4.1.19-RXN go-plus.json cyclodextrin glucanotransferase|beta-cyclodextrin glycosyltransferase|1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)|CGTase|alpha-cyclodextrin glucanotransferase|alpha-cyclodextrin glycosyltransferase|Bacillus macerans amylase|cyclomaltodextrin glycosyltransferase|BMA|cyclomaltodextrin glucotransferase|alpha-1,4-glucan 4-glycosyltransferase, cyclizing|gamma-cyclodextrin glycosyltransferase|beta-cyclodextrin glucanotransferase|neutral-cyclodextrin glycosyltransferase|konchizaimu|cyclodextrin glycosyltransferase http://purl.obolibrary.org/obo/GO_0043895 GO:0043890 biolink:MolecularActivity N-acetylgalactosamine-6-sulfatase activity Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Reactome:R-HSA-1630304|MetaCyc:3.1.6.4-RXN|Reactome:R-HSA-2263490|EC:3.1.6.4 go-plus.json N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity|chondroitinase|galactose-6-sulfate sulfatase activity|acetylgalactosamine 6-sulfatase activity|chondroitinsulfatase|N-acetylgalactosamine 6-sulfatase activity|N-acetylgalactosamine-6-sulfate sulfatase activity|chondroitin sulfatase http://purl.obolibrary.org/obo/GO_0043890 GO:0102557 biolink:MolecularActivity protopanaxadiol 6-hydroxylase activity Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O. RHEA:22272|MetaCyc:RXN-14978|EC:1.14.14.121 go-plus.json http://purl.obolibrary.org/obo/GO_0102557 GO:0102556 biolink:MolecularActivity dammarenediol 12-hydroxylase activity Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O. MetaCyc:RXN-14975|EC:1.14.14.120|RHEA:38579 go-plus.json http://purl.obolibrary.org/obo/GO_0102556 GO:0043892 biolink:MolecularActivity methylglyoxal reductase (NADPH-dependent) activity Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+. MetaCyc:1.1.1.283-RXN|EC:1.1.1.283|MetaCyc:RXN-8636|RHEA:21748 go-plus.json lactaldehyde dehydrogenase (NADP+)|Gre2|lactaldehyde:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0043892 GO:0102559 biolink:MolecularActivity protein-(glutamine-N5) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine. EC:2.1.1.297|MetaCyc:RXN-14992|RHEA:42896 go-plus.json http://purl.obolibrary.org/obo/GO_0102559 GO:0043891 biolink:MolecularActivity glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+. MetaCyc:GAPDHSYNEC-RXN|EC:1.2.1.59 go-plus.json glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)|D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)|triosephosphate dehydrogenase (NAD(P))|triosephosphate dehydrogenase (NAD(P)+)|NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0043891 OBO:GOCHE_35703 biolink:OntologyClass substance with xenobiotic role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35703 3_STAR GO:0043898 biolink:MolecularActivity 2,3-dihydroxybiphenyl 1,2-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid. go-plus.json BphC|2,3-dihydroxybiphenyl-1,2-dioxygenase activity http://purl.obolibrary.org/obo/GO_0043898 GO:0043897 biolink:MolecularActivity glucan 1,4-alpha-maltohydrolase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains. EC:3.2.1.133|MetaCyc:3.2.1.133-RXN go-plus.json glucan-1,4-alpha-maltohydrolase activity|maltogenic alpha-amylase activity|1,4-alpha-D-glucan alpha-maltohydrolase activity http://purl.obolibrary.org/obo/GO_0043897 GO:0043899 biolink:MolecularActivity phosphoserine:homoserine phosphotransferase activity Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine. go-plus.json thrH http://purl.obolibrary.org/obo/GO_0043899 GO:0102560 biolink:MolecularActivity 5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+. RHEA:41612|EC:3.1.4.57|MetaCyc:RXN-14995 go-plus.json phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase http://purl.obolibrary.org/obo/GO_0102560 GO:0102562 biolink:MolecularActivity hydroxyproline O-arbinofuranose transferase activity Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline. RHEA:49472|MetaCyc:RXN-15011 go-plus.json http://purl.obolibrary.org/obo/GO_0102562 GO:0102561 biolink:MolecularActivity D-ribose 2,5-bisphosphate 2-phosphohydrolase activity Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate. EC:3.1.4.57|MetaCyc:RXN-14996|RHEA:41616 go-plus.json http://purl.obolibrary.org/obo/GO_0102561 GO:0102564 biolink:MolecularActivity aurachin C epoxide hydrolase/isomerase activity Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P). MetaCyc:RXN-15030|RHEA:48728 go-plus.json http://purl.obolibrary.org/obo/GO_0102564 GO:0102563 biolink:MolecularActivity aurachin C monooxygenase activity Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P). MetaCyc:RXN-15029 go-plus.json http://purl.obolibrary.org/obo/GO_0102563 GO:0102566 biolink:MolecularActivity 1-acyl dihydroxyacetone phosphate reductase activity Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP. EC:1.1.1.101|MetaCyc:RXN-15046 go-plus.json http://purl.obolibrary.org/obo/GO_0102566 GO:0102568 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102568 GO:0102567 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0102567 GO:0102569 biolink:MolecularActivity FR-33289 synthase activity Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide. MetaCyc:RXN-15082 go-plus.json http://purl.obolibrary.org/obo/GO_0102569 OBO:GOCHE_35718 biolink:OntologyClass substance with antifungal agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_35718 3_STAR GO:0102571 biolink:MolecularActivity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [glycoprotein]-(L-serine/L-threonine). MetaCyc:RXN-15215|EC:3.2.1.169 go-plus.json http://purl.obolibrary.org/obo/GO_0102571 GO:0102570 biolink:MolecularActivity tyrosine:phenylpyruvate aminotransferase activity Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine = L-phenylalanine + 3-(4-hydroxyphenyl)pyruvate. MetaCyc:RXN-15200 go-plus.json http://purl.obolibrary.org/obo/GO_0102570 GO:0102573 biolink:MolecularActivity aminodeoxyfutalosine synthase activity Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O <=> aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+. EC:2.5.1.120|MetaCyc:RXN-15264|RHEA:33075 go-plus.json http://purl.obolibrary.org/obo/GO_0102573 GO:0102572 biolink:MolecularActivity N-glutamylanilide hydrolase activity Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+. MetaCyc:RXN-15251|RHEA:50684 go-plus.json http://purl.obolibrary.org/obo/GO_0102572 GO:0102575 biolink:MolecularActivity 3-oxo-dodecanoyl-ACP hydrolase activity Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein]. MetaCyc:RXN-15281 go-plus.json http://purl.obolibrary.org/obo/GO_0102575 GO:0102574 biolink:MolecularActivity 3-oxo-myristoyl-ACP hydrolase activity Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein]. MetaCyc:RXN-15280 go-plus.json http://purl.obolibrary.org/obo/GO_0102574 GO:0102577 biolink:MolecularActivity 3-oxo-palmitate decarboxylase activity Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide. MetaCyc:RXN-15283|EC:4.1.1.56 go-plus.json http://purl.obolibrary.org/obo/GO_0102577 GO:0102576 biolink:MolecularActivity 3-oxo-palmitoyl-ACP hydrolase activity Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein]. MetaCyc:RXN-15282 go-plus.json http://purl.obolibrary.org/obo/GO_0102576 NCBITaxon:55824 biolink:OrganismalEntity Hirudinea go-plus.json leeches http://purl.obolibrary.org/obo/NCBITaxon_55824 PO:0005029 biolink:OntologyClass root primordium A primordium (PO:0025127) that develops from a root anlagen (PO:0025433) and is committed to the development of a root (PO:0009005). go-plus.json primordio de raíz (Spanish, exact)|根原基（可視的） (Japanese, exact)|root primordia (exact, plural)|portion of root primordium tissue (exact) http://purl.obolibrary.org/obo/PO_0005029 GO:0102580 biolink:MolecularActivity cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP. EC:2.4.2.51|RHEA:35443|MetaCyc:RXN-15326 go-plus.json http://purl.obolibrary.org/obo/GO_0102580 GO:0102582 biolink:MolecularActivity cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+. MetaCyc:RXN-15328 go-plus.json http://purl.obolibrary.org/obo/GO_0102582 GO:0102581 biolink:MolecularActivity cyanidin 3-O-glucoside-p-coumaroyltransferase activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A. MetaCyc:RXN-15327 go-plus.json http://purl.obolibrary.org/obo/GO_0102581 GO:0102584 biolink:MolecularActivity cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+. MetaCyc:RXN-15330 go-plus.json http://purl.obolibrary.org/obo/GO_0102584 GO:0102583 biolink:MolecularActivity cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A. MetaCyc:RXN-15329 go-plus.json http://purl.obolibrary.org/obo/GO_0102583 GO:0102586 biolink:MolecularActivity cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose. MetaCyc:RXN-15332 go-plus.json http://purl.obolibrary.org/obo/GO_0102586 GO:0102585 biolink:MolecularActivity cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A. MetaCyc:RXN-15331 go-plus.json http://purl.obolibrary.org/obo/GO_0102585 GO:0102588 biolink:MolecularActivity cyanidin 3-O-glucoside 6''-O-malonyltransferase activity Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A. EC:2.3.1.171|MetaCyc:RXN-15335 go-plus.json http://purl.obolibrary.org/obo/GO_0102588 GO:0102587 biolink:MolecularActivity cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+. MetaCyc:RXN-15333 go-plus.json http://purl.obolibrary.org/obo/GO_0102587 GO:0102589 biolink:MolecularActivity cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A. MetaCyc:RXN-15336 go-plus.json http://purl.obolibrary.org/obo/GO_0102589 NCBITaxon:219121 biolink:OrganismalEntity Cichorieae go-plus.json Lactuceae http://purl.obolibrary.org/obo/NCBITaxon_219121 NCBITaxon:219120 biolink:OrganismalEntity Cichorioideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_219120 CHEBI:20441 biolink:ChemicalSubstance 4-(methylamino)butyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20441 GO:0018807 biolink:MolecularActivity 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA. UM-BBD_reactionID:r0204|EC:3.7.1.21|RHEA:39651 go-plus.json http://purl.obolibrary.org/obo/GO_0018807 GO:0018806 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018806 GO:0018809 biolink:MolecularActivity E-phenylitaconyl-CoA hydratase activity Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA. UM-BBD_reactionID:r0331 go-plus.json http://purl.obolibrary.org/obo/GO_0018809 GO:0018808 biolink:MolecularActivity trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde. UM-BBD_reactionID:r0484 go-plus.json http://purl.obolibrary.org/obo/GO_0018808 GO:0018803 biolink:MolecularActivity 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate. EC:4.1.2.34|UM-BBD_reactionID:r0487|RHEA:16453|MetaCyc:4.1.2.34-RXN go-plus.json (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)|2'-carboxybenzalpyruvate aldolase activity|(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity|trans-2'-carboxybenzalpyruvate hydratase-aldolase activity|(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0018803 UBERON:0005233 biolink:AnatomicalEntity medial-nasal process ectoderm An ectoderm that is part of a medial nasal prominence [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005233 GO:0018802 biolink:MolecularActivity 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde. UM-BBD_reactionID:r0370 go-plus.json http://purl.obolibrary.org/obo/GO_0018802 GO:0018805 biolink:MolecularActivity benzylsuccinate synthase activity Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate. MetaCyc:RXN-863|UM-BBD_enzymeID:e0259|EC:4.1.99.11|RHEA:10416|KEGG_REACTION:R05598 go-plus.json benzylsuccinate fumarate-lyase activity|benzylsuccinate fumarate-lyase (toluene-forming) http://purl.obolibrary.org/obo/GO_0018805 GO:0018804 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018804 GO:0018801 biolink:MolecularActivity glutaconyl-CoA decarboxylase activity Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2). UM-BBD_reactionID:r0199|KEGG_REACTION:R03028|EC:7.2.4.5|RHEA:23972|MetaCyc:GLUTACONYL-COA-DECARBOXYLASE-RXN go-plus.json glutaconyl coenzyme A decarboxylase activity|4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)|4-carboxybut-2-enoyl-CoA carboxy-lyase activity|pent-2-enoyl-CoA carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0018801 GO:0018800 biolink:MolecularActivity 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2. EC:4.1.1.68|UM-BBD_reactionID:r0367|RHEA:14397|MetaCyc:4.1.1.68-RXN go-plus.json HpaG2|OPET decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity|HpaG-2|5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)|5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity http://purl.obolibrary.org/obo/GO_0018800 CHEBI:19448 biolink:ChemicalSubstance 2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19448 UBERON:0005239 biolink:AnatomicalEntity basal plate metencephalon go-plus.json metencephalon basal plate http://purl.obolibrary.org/obo/UBERON_0005239 UBERON:0005234 biolink:AnatomicalEntity optic eminence ectoderm An ectoderm that is part of a optic eminence [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005234 CHEBI:44400 biolink:ChemicalSubstance 2-iminiopropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_44400 chebi_ph7_3 GO:0018818 biolink:MolecularActivity acetylene hydratase activity Catalysis of the reaction: acetaldehyde = acetylene + H(2)O. UM-BBD_reactionID:r0591|MetaCyc:R141-RXN|RHEA:17885|EC:4.2.1.112|KEGG_REACTION:R05380 go-plus.json AH|acetaldehyde hydro-lyase activity|AHy http://purl.obolibrary.org/obo/GO_0018818 GO:0018817 biolink:MolecularActivity 2-oxo-hept-3-ene-1,7-dioate hydratase activity Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate. RHEA:42072|UM-BBD_reactionID:r0369|MetaCyc:HYDROXYHEPTA-DIENEDIOATE-HYDROXY-RXN go-plus.json 2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity|HpaH|2-oxo-hepta-3-ene-1,7-dioate hydratase activity http://purl.obolibrary.org/obo/GO_0018817 GO:0018819 biolink:MolecularActivity lactoyl-CoA dehydratase activity Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O. EC:4.2.1.54|UM-BBD_reactionID:r0086|RHEA:21056|MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN|MetaCyc:RXN-781 go-plus.json lactoyl-CoA hydro-lyase activity|lactyl CoA dehydratase activity|lactoyl coenzyme A dehydratase activity|lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)|lactyl-coenzyme A dehydrase activity|acrylyl coenzyme A hydratase activity http://purl.obolibrary.org/obo/GO_0018819 GO:0018814 biolink:MolecularActivity phenylacetaldoxime dehydratase activity Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile. KEGG_REACTION:R07638|RHEA:20069|EC:4.99.1.7|MetaCyc:4.99.1.7-RXN|UM-BBD_reactionID:r0697 go-plus.json (Z)-phenylacetaldehyde-oxime hydro-lyase activity|arylacetaldoxime dehydratase activity|PAOx dehydratase activity|(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity|OxdB http://purl.obolibrary.org/obo/GO_0018814 UBERON:0005222 biolink:AnatomicalEntity liver left lobe parenchyma A parenchyma that is part of a left lobe of liver [Automatically generated definition]. go-plus.json parenchyma of left lobe of liver http://purl.obolibrary.org/obo/UBERON_0005222 GO:0018813 biolink:MolecularActivity trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde). RHEA:27389|UM-BBD_enzymeID:e0257|EC:4.1.2.45 go-plus.json http://purl.obolibrary.org/obo/GO_0018813 UBERON:0005221 biolink:AnatomicalEntity liver right lobe parenchyma A parenchyma that is part of a right lobe of liver [Automatically generated definition]. go-plus.json parenchyma of right lobe of liver http://purl.obolibrary.org/obo/UBERON_0005221 CHEBI:44409 biolink:ChemicalSubstance NADP zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_44409 GO:0018816 biolink:MolecularActivity 2-hydroxyisobutyrate dehydratase activity Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate. UM-BBD_reactionID:r0618 go-plus.json http://purl.obolibrary.org/obo/GO_0018816 GO:0018815 biolink:MolecularActivity 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine. UM-BBD_reactionID:r0051|MetaCyc:RXN-645 go-plus.json http://purl.obolibrary.org/obo/GO_0018815 GO:0018810 biolink:MolecularActivity trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene. UM-BBD_reactionID:r0164 go-plus.json http://purl.obolibrary.org/obo/GO_0018810 GO:0018812 biolink:MolecularActivity 3-hydroxyacyl-CoA dehydratase activity Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA). Reactome:R-HSA-8957389 go-plus.json http://purl.obolibrary.org/obo/GO_0018812 GO:0018811 biolink:MolecularActivity cyclohex-1-ene-1-carboxyl-CoA hydratase activity Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA. MetaCyc:R266-RXN|UM-BBD_reactionID:r0191 go-plus.json http://purl.obolibrary.org/obo/GO_0018811 UBERON:0005229 biolink:AnatomicalEntity lower leg epithelium An epithelium that is part of a lower leg [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005229 NCBITaxon:7664 biolink:OrganismalEntity Strongylocentrotus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7664 UBERON:0005228 biolink:AnatomicalEntity upper arm epithelium An epithelium that is part of a forelimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005228 UBERON:0005227 biolink:AnatomicalEntity manual digit epithelium An epithelium that is part of a finger [Automatically generated definition]. go-plus.json fore limb digit epithelium|finger epithelium|hand digit epithelium http://purl.obolibrary.org/obo/UBERON_0005227 UBERON:0005226 biolink:AnatomicalEntity pedal digit epithelium An epithelium that is part of a toe [Automatically generated definition]. go-plus.json hind limb digit epithelium|toe epithelium|foot digit epithelium http://purl.obolibrary.org/obo/UBERON_0005226 CHEBI:19432 biolink:ChemicalSubstance 2-acetamidofluorenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_19432 UBERON:0005225 biolink:AnatomicalEntity upper leg epithelium An epithelium that is part of a hindlimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005225 CHEBI:19471 biolink:ChemicalSubstance 2-aminohexano-6-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_19471 NCBITaxon:7625 biolink:OrganismalEntity Echinoidea go-plus.json sea urchins|sea urchin|sea urchins http://purl.obolibrary.org/obo/NCBITaxon_7625 NCBITaxon:7624 biolink:OrganismalEntity Echinozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7624 UBERON:0005211 biolink:AnatomicalEntity renal medulla interstitium tissue surrounding the loop of Henle in the renal medulla. go-plus.json renal medullary interstitium|medullary stroma|kidney medulla interstitium|medullary interstitium|renal medullary interstitial tissue http://purl.obolibrary.org/obo/UBERON_0005211 UBERON:0005219 biolink:AnatomicalEntity hindbrain subarachnoid space A subarachnoid space that is part of a hindbrain [Automatically generated definition]. go-plus.json subarachnoid space hindbrain|subarachnoid space rhombencephalon http://purl.obolibrary.org/obo/UBERON_0005219 UBERON:0005218 biolink:AnatomicalEntity diencephalon subarachnoid space A subarachnoid space that is part of a diencephalon [Automatically generated definition]. go-plus.json subarachnoid space diencephalon http://purl.obolibrary.org/obo/UBERON_0005218 UBERON:0005217 biolink:AnatomicalEntity midbrain subarachnoid space A subarachnoid space that is part of a midbrain [Automatically generated definition]. go-plus.json subarachnoid space midbrain|subarachnoid space mesencephalon http://purl.obolibrary.org/obo/UBERON_0005217 UBERON:0005216 biolink:AnatomicalEntity optic eminence surface ectoderm An external ectoderm that is part of a optic eminence [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005216 UBERON:0005215 biolink:AnatomicalEntity kidney interstitium The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes. go-plus.json renal interstitium|renal stroma|renal interstitial tissue|interstitial tissue of kidney|kidney interstitium group|stroma of kidney http://purl.obolibrary.org/obo/UBERON_0005215 UBERON:0005214 biolink:AnatomicalEntity inner renal medulla interstitium A portion of interstitial tissue that is part of a inner medulla of kidney [Automatically generated definition]. go-plus.json kidney inner medulla interstitium|inner medullary interstitium|papillary interstitium http://purl.obolibrary.org/obo/UBERON_0005214 UBERON:0005213 biolink:AnatomicalEntity outer renal medulla interstitium A portion of interstitial tissue that is part of a outer medulla of kidney [Automatically generated definition]. go-plus.json kidney outer medulla interstitium|outer medullary interstitium http://purl.obolibrary.org/obo/UBERON_0005213 UBERON:0005212 biolink:AnatomicalEntity Leydig cell region of testis The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.. go-plus.json interstitium of the testis|testis - interstitial|interstitium of testis|testis interstitium|testis interstitial tissue http://purl.obolibrary.org/obo/UBERON_0005212 NCBITaxon:7638 biolink:OrganismalEntity Euechinoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7638 CHEBI:20432 biolink:ChemicalSubstance imidazolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_20432 GO:0043803 biolink:MolecularActivity hydroxyneurosporene-O-methyltransferase activity Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + spheroidene. EC:2.1.1.210|RHEA:30903 go-plus.json demethylspheroidene O-methyltransferase|1-hydroxycarotenoid O-methylase|1-hydroxycarotenoid methylase|1-HO-carotenoid methylase http://purl.obolibrary.org/obo/GO_0043803 UBERON:0005200 biolink:AnatomicalEntity thoracic mammary gland A lactiferous gland that is located in the thoracic region/breast. go-plus.json lactiferous gland|mammary gland|anterior mammary gland|breast mammary gland http://purl.obolibrary.org/obo/UBERON_0005200 GO:0043802 biolink:MolecularActivity hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate. EC:6.3.5.9|RHEA:12544|MetaCyc:R341-RXN|KEGG_REACTION:R05224 go-plus.json hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity|hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)|CobB http://purl.obolibrary.org/obo/GO_0043802 GO:0043805 biolink:MolecularActivity indolepyruvate ferredoxin oxidoreductase activity Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin. MetaCyc:1.2.7.8-RXN|RHEA:12645|EC:1.2.7.8 go-plus.json indolepyruvate oxidoreductase activity|3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)|3-(indol-3-yl)pyruvate synthase (ferredoxin) activity|IOR http://purl.obolibrary.org/obo/GO_0043805 GO:0043804 biolink:MolecularActivity imidazolone hydrolase activity Catalysis of the reaction: N-formimidoylglycine => H2O + imidazol-4-one. RHEA:24935 go-plus.json http://purl.obolibrary.org/obo/GO_0043804 GO:0043801 biolink:MolecularActivity hexulose-6-phosphate synthase activity Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate. MetaCyc:R10-RXN|EC:4.1.2.43|RHEA:25201 go-plus.json http://purl.obolibrary.org/obo/GO_0043801 GO:0043800 biolink:MolecularActivity hexulose-6-phosphate isomerase activity Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate. MetaCyc:R12-RXN|EC:5.3.1.27|RHEA:25900 go-plus.json HUMPI http://purl.obolibrary.org/obo/GO_0043800 UBERON:0005208 biolink:AnatomicalEntity right atrium valve A valve that is part of a right atrium [Automatically generated definition]. go-plus.json superior vena cava valve|valve of right atrium|right atrium valves http://purl.obolibrary.org/obo/UBERON_0005208 UBERON:0005206 biolink:AnatomicalEntity choroid plexus stroma Stromal matrix surrounding blood vessels within the choroid plexus. go-plus.json choroid plexus stromal matrix http://purl.obolibrary.org/obo/UBERON_0005206 UBERON:0005205 biolink:AnatomicalEntity lamina propria of vagina go-plus.json vagina stroma http://purl.obolibrary.org/obo/UBERON_0005205 GO:0043807 biolink:MolecularActivity 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin. MetaCyc:1.2.7.7-RXN|RHEA:11712|EC:1.2.7.7 go-plus.json 2-oxoisovalerate ferredoxin reductase activity|branched-chain ketoacid ferredoxin reductase activity|2-ketoisovalerate ferredoxin reductase activity|keto-valine-ferredoxin oxidoreductase activity|3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)|ketoisovalerate ferredoxin reductase activity|3-methyl-2-oxobutanoate synthase (ferredoxin) activity|VOR|ketoisovalerate oxidoreductase activity|branched-chain oxo acid ferredoxin reductase activity http://purl.obolibrary.org/obo/GO_0043807 UBERON:0005204 biolink:AnatomicalEntity larynx submucosa gland A gland that is part of a larynx submucosa [Automatically generated definition]. go-plus.json laryngeal submucosa gland http://purl.obolibrary.org/obo/UBERON_0005204 GO:0043806 biolink:MolecularActivity keto acid formate lyase activity Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate. EC:2.3.1.-|MetaCyc:KETOBUTFORMLY-RXN go-plus.json keto-acid formate lyase activity|keto-acid formate acetyltransferase|keto-acid formate-lyase activity http://purl.obolibrary.org/obo/GO_0043806 NCBITaxon:2704949 biolink:OrganismalEntity Trypanosomatida go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2704949 UBERON:0005203 biolink:AnatomicalEntity trachea gland a tubuloacinar seromucous gland that is located principally in the submucosa of the trachea. Excretory ducts from this gland pass through the lamina propria to the tracheal lumen. go-plus.json glandula trachealis|tracheal gland|tubular seromucous gland of trachea http://purl.obolibrary.org/obo/UBERON_0005203 GO:0043809 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043809 UBERON:0005202 biolink:AnatomicalEntity distal straight tubule macula densa A macula densa that is part of an ascending limb of loop of Henle [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005202 GO:0043808 biolink:MolecularActivity lyso-ornithine lipid acyltransferase activity Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein]. go-plus.json http://purl.obolibrary.org/obo/GO_0043808 UBERON:0005277 biolink:AnatomicalEntity dorsal skin of toe A dorsal skin of digit that is part of a pedal digit. go-plus.json skin of dorsal part of toe|subdivision of skin of dorsal part of toe|dorsal toe skin http://purl.obolibrary.org/obo/UBERON_0005277 GO:0043814 biolink:MolecularActivity phospholactate guanylyltransferase activity Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate. MetaCyc:RXN-8077|EC:2.7.7.68|RHEA:30519 go-plus.json http://purl.obolibrary.org/obo/GO_0043814 UBERON:0005276 biolink:AnatomicalEntity dorsal skin of finger A dorsal skin of digit that is part of a manual digit. go-plus.json dorsal finger skin|skin of dorsal part of finger|subdivision of skin of dorsal part of finger http://purl.obolibrary.org/obo/UBERON_0005276 GO:0043813 biolink:MolecularActivity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate. Reactome:R-HSA-1676005|Reactome:R-HSA-1676174|Reactome:R-HSA-1675836|Reactome:R-HSA-1676020 go-plus.json phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity http://purl.obolibrary.org/obo/GO_0043813 GO:0043816 biolink:MolecularActivity phosphoserine-tRNA(Cys) ligase activity Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys). EC:6.1.1.27|RHEA:25678 go-plus.json O-phosphoseryl-tRNA(Cys) synthetase activity|phosphoserine--tRNA(Cys) ligase activity|phosphoserine-tRNACys ligase activity|SepRS http://purl.obolibrary.org/obo/GO_0043816 UBERON:0005275 biolink:AnatomicalEntity dorsal skin of digit go-plus.json dorsal digit skin|skin of dorsal part of digit http://purl.obolibrary.org/obo/UBERON_0005275 GO:0043815 biolink:MolecularActivity phosphoribosylglycinamide formyltransferase 2 activity Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate. RHEA:24829|MetaCyc:GARTRANSFORMYL2-RXN go-plus.json formate-dependent GAR transformylase activity|GAR transformylase 2|GART 2|5'-phosphoribosylglycinamide transformylase 2 http://purl.obolibrary.org/obo/GO_0043815 GO:0043810 biolink:MolecularActivity ornithine-acyl [acyl carrier protein] N-acyltransferase activity Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids. RHEA:20633|EC:2.3.2.30 go-plus.json L-ornithine N(alpha)-acyltransferase|ornithine-acyl[acyl carrier protein] N-acyltransferase activity http://purl.obolibrary.org/obo/GO_0043810 GO:0043812 biolink:MolecularActivity phosphatidylinositol-4-phosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate. go-plus.json phosphatidylinositol 4-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0043812 UBERON:0005270 biolink:AnatomicalEntity renal cortex interstitium A compartment of the renal cortex situated between basement membranes of epithelia and vessels that contains two contiguous cellular networks in mutual contact, one formed by interstitial fibroblasts, the other by dendritic cells. go-plus.json renal cortical interstitial tissue|cortical stroma|kidney cortex interstitium http://purl.obolibrary.org/obo/UBERON_0005270 GO:0043811 biolink:MolecularActivity phosphate:acyl-[acyl carrier protein] acyltransferase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein]. go-plus.json http://purl.obolibrary.org/obo/GO_0043811 GO:0043818 biolink:MolecularActivity precorrin-3B synthase activity Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B. KEGG_REACTION:R05217|MetaCyc:R321-RXN|RHEA:17293|EC:1.14.13.83 go-plus.json precorrin-3X synthase activity|CobG|precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating) http://purl.obolibrary.org/obo/GO_0043818 GO:0043817 biolink:MolecularActivity phosphosulfolactate synthase activity Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite. MetaCyc:R228-RXN|RHEA:22784|KEGG_REACTION:R07476|MetaCyc:4.4.1.19-RXN|EC:4.4.1.19 go-plus.json (2R)-O-phospho-3-sulfolactate sulfo-lyase activity|(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)|(2R)-phospho-3-sulfolactate synthase activity|PSL synthase activity http://purl.obolibrary.org/obo/GO_0043817 GO:0043819 biolink:MolecularActivity precorrin-6A synthase (deacetylating) activity Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X. KEGG_REACTION:R05219|MetaCyc:R322-RXN|RHEA:18261|EC:2.1.1.152 go-plus.json CobF|precorrin-6X synthase (deacetylating) activity|S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating) http://purl.obolibrary.org/obo/GO_0043819 NCBITaxon:55885 biolink:OrganismalEntity Peloderinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_55885 CHEBI:68438 biolink:ChemicalSubstance Fe-coproporphyrin III(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68438 chebi_ph7_3 CHEBI:68437 biolink:ChemicalSubstance 5,6,7,8-tetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68437 chebi_ph7_3 GO:0043825 biolink:MolecularActivity succinylornithine transaminase activity Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate. MetaCyc:SUCCORNTRANSAM-RXN|KEGG_REACTION:R04217|RHEA:16953|EC:2.6.1.81 go-plus.json succinyl ornithine transaminase activity|AstC|succinylornithine aminotransferase activity|N2-succinylornithine 5-aminotransferase activity|succinyl-ornithine transaminase activity|N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|N(2)-succinylornithine 5-aminotransferase activity|SOAT http://purl.obolibrary.org/obo/GO_0043825 GO:0043824 biolink:MolecularActivity succinylglutamate-semialdehyde dehydrogenase activity Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH. RHEA:10812|MetaCyc:SUCCGLUALDDEHYD-RXN|EC:1.2.1.71|KEGG_REACTION:R05049 go-plus.json SGSD|succinyl glutamate-semialdehyde dehydrogenase activity|AstD|AruD|N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity|succinylglutamic semialdehyde dehydrogenase activity|N-succinylglutamate 5-semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0043824 GO:0043827 biolink:MolecularActivity tRNA (adenine-57, 58-N(1)-) methyltransferase activity Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA. go-plus.json TrmI|tRNA (adenine-57, 58 N1-) methyltransferase activity|tRNA (m1A) MTase|tRNA (adenine-57, 58-N1-) methyltransferase activity http://purl.obolibrary.org/obo/GO_0043827 GO:0043826 biolink:MolecularActivity sulfur oxygenase reductase activity Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+. MetaCyc:RXN-8226 go-plus.json sulphur oxygenase reductase activity|SOR http://purl.obolibrary.org/obo/GO_0043826 UBERON:0005263 biolink:AnatomicalEntity outflow tract cardiac jelly A cardiac jelly that is part of a outflow tract [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005263 GO:0043821 biolink:MolecularActivity propionyl-CoA:succinate CoA-transferase activity Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate. RHEA:28010|MetaCyc:RXN0-268 go-plus.json propionyl-CoA:succinate CoA transferase activity|propionyl-CoA succinate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0043821 UBERON:0005262 biolink:AnatomicalEntity ventricle cardiac jelly A cardiac jelly that is part of a ventricle [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005262 UBERON:0005261 biolink:AnatomicalEntity atrium cardiac jelly A cardiac jelly that is part of an atrium [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005261 GO:0043820 biolink:MolecularActivity propionyl-CoA dehydrogenase activity Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA. EC:1.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0043820 GO:0043823 biolink:MolecularActivity spheroidene monooxygenase activity Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O. MetaCyc:RXN-10670|RHEA:33027|EC:1.14.15.9 go-plus.json http://purl.obolibrary.org/obo/GO_0043823 GO:0043822 biolink:MolecularActivity ribonuclease M5 activity Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor. MetaCyc:3.1.26.8-RXN|EC:3.1.26.8 go-plus.json 5S ribosomal maturation nuclease activity|5S ribosomal RNA maturation endonuclease activity|RNase M5 activity http://purl.obolibrary.org/obo/GO_0043822 GO:0043829 biolink:MolecularActivity tRNA-specific adenosine-37 deaminase activity Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule. go-plus.json TAD1|tRNA-specific adenosine deaminase 1|tRNA(Ala)-A37 deaminase activity http://purl.obolibrary.org/obo/GO_0043829 UBERON:0005269 biolink:AnatomicalEntity renal cortex vein Artery that receives blood from the renal cortex[MP, modified] go-plus.json renal cortex venous system|kidney cortex vein http://purl.obolibrary.org/obo/UBERON_0005269 GO:0043828 biolink:MolecularActivity tRNA 2-selenouridine synthase activity Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA). RHEA:42716|MetaCyc:RXN0-2281|EC:2.9.1.3 go-plus.json http://purl.obolibrary.org/obo/GO_0043828 UBERON:0005268 biolink:AnatomicalEntity renal cortex artery An artery that supplies the renal cortex. go-plus.json renal cortex artery|kidney cortex artery|renal cortex arterial system http://purl.obolibrary.org/obo/UBERON_0005268 NCBITaxon:7668 biolink:OrganismalEntity Strongylocentrotus purpuratus go-plus.json purple sea urchin|purple urchin http://purl.obolibrary.org/obo/NCBITaxon_7668 GO:0043830 biolink:MolecularActivity thiol-driven fumarate reductase activity Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide. EC:1.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0043830 CHEBI:68448 biolink:ChemicalSubstance beta-D-GalpNAc-(1->4)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_68448 chebi_ph7_3 GO:0043836 biolink:MolecularActivity xanthine hydrolase activity Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate. MetaCyc:R127-RXN go-plus.json xanthinase activity http://purl.obolibrary.org/obo/GO_0043836 UBERON:0005255 biolink:AnatomicalEntity pedal digit mesenchyme Mesenchyme that is part of a developing toe [Automatically generated definition]. go-plus.json pedal digital ray mesenchyme|hind limb digit mesenchyme|toe mesenchyme|foot digit mesenchyme|finger ray mesenchyme http://purl.obolibrary.org/obo/UBERON_0005255 UBERON:0005254 biolink:AnatomicalEntity upper leg mesenchyme Mesenchyme that is part of a developing hindlimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005254 GO:0043835 biolink:MolecularActivity obsolete uracil/thymine dehydrogenase activity OBSOLETE. Catalysis of the reactions: uracil + H2O + acceptor = barbiturate + reduced acceptor; and thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor. EC:1.17.99.4 go-plus.json uracil-thymine oxidase activity|uracil:acceptor oxidoreductase activity|uracil oxidase activity|uracil/thymine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0043835 UBERON:0005253 biolink:AnatomicalEntity head mesenchyme Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. go-plus.json desmocranium|cranial mesenchyme|cephalic mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 GO:0043838 biolink:MolecularActivity phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol. go-plus.json phosphoethanolamine transferase|EptB http://purl.obolibrary.org/obo/GO_0043838 GO:0043837 biolink:MolecularActivity valine dehydrogenase (NAD) activity Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH. RHEA:30763|EC:1.4.1.23 go-plus.json ValDH http://purl.obolibrary.org/obo/GO_0043837 NCBITaxon:41294 biolink:OrganismalEntity Bradyrhizobiaceae go-plus.json Bradyrhizobium group|BANA domain|alpha-2 proteobacteria http://purl.obolibrary.org/obo/NCBITaxon_41294 UBERON:0005251 biolink:AnatomicalEntity yolk sac cavity An anatomical cavity that is part of a yolk sac [Automatically generated definition]. go-plus.json yolk sac space|cavity of yolk sac|yolk sac lumen http://purl.obolibrary.org/obo/UBERON_0005251 GO:0043832 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043832 GO:0043831 biolink:MolecularActivity thiosulfate dehydrogenase (quinone) activity Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate. EC:1.8.5.2|KEGG_REACTION:R07177|RHEA:10936|MetaCyc:1.8.5.2-RXN go-plus.json TQO|thiosulphate:quinone oxidoreductase activity|thiosulfate:6-decylubiquinone oxidoreductase activity|thiosulphate dehydrogenase (quinone) activity|thiosulfate:quinone oxidoreductase activity|thiosulfate oxidoreductase, tetrathionate-forming activity|DoxD|DoxA http://purl.obolibrary.org/obo/GO_0043831 UBERON:0005250 biolink:AnatomicalEntity stomatodeum gland A gland that is part of a stomodeum. go-plus.json stomatodaeum gland http://purl.obolibrary.org/obo/UBERON_0005250 GO:0043834 biolink:MolecularActivity trimethylamine methyltransferase activity Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine. RHEA:39287|EC:2.1.1.250|MetaCyc:RXN-8102 go-plus.json TMA methyltransferase 1|trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|MT1|trimethylamine:corrinoid methyltransferase activity|mttB1 http://purl.obolibrary.org/obo/GO_0043834 GO:0043833 biolink:MolecularActivity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M. EC:2.1.1.247|MetaCyc:RXN-8103|MetaCyc:RXN-8101|MetaCyc:RXN-8099 go-plus.json methylamine-specific methylcobalamin:CoM methyltransferase activity|methylcobamide:CoM methyltransferase II isozyme A|methylcobamide:coenzyme M methyltransferase activity|monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|methylcobamide:CoM methyltransferase activity http://purl.obolibrary.org/obo/GO_0043833 NCBITaxon:7675 biolink:OrganismalEntity Echinidea go-plus.json Echinoida http://purl.obolibrary.org/obo/NCBITaxon_7675 NCBITaxon:7674 biolink:OrganismalEntity Echinacea go-plus.json Echinacea http://purl.obolibrary.org/obo/NCBITaxon_7674 UBERON:0005259 biolink:AnatomicalEntity lower leg mesenchyme Mesenchyme that is part of a developing lower leg [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005259 GO:0043839 biolink:MolecularActivity lipid A phosphate methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A. go-plus.json lipid A phosphomethyltransferase activity|lipid A methyltransferase|LmtA|lipid A 1-phosphomethyltransferase activity http://purl.obolibrary.org/obo/GO_0043839 UBERON:0005258 biolink:AnatomicalEntity upper arm mesenchyme Mesenchyme that is part of a developing forelimb stylopod [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005258 UBERON:0005257 biolink:AnatomicalEntity manual digit mesenchyme Mesenchyme that is part of a developing finger [Automatically generated definition]. go-plus.json anterior limb digital ray mesenchyme|fore limb digit mesenchyme|finger mesenchyme|manual digital ray mesenchyme|hand digit mesenchyme|finger ray mesenchyme http://purl.obolibrary.org/obo/UBERON_0005257 UBERON:0005256 biolink:AnatomicalEntity trunk mesenchyme Mesenchyme that is part of a developing trunk. go-plus.json trunk and cervical mesenchyme http://purl.obolibrary.org/obo/UBERON_0005256 CHEBI:68452 biolink:ChemicalSubstance azole go-plus.json http://purl.obolibrary.org/obo/CHEBI_68452 CHEBI:68458 biolink:ChemicalSubstance multi-methyl-branched fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68458 GO:0043841 biolink:MolecularActivity (S)-lactate 2-kinase activity Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP. MetaCyc:RXN-8076 go-plus.json lactate 2-kinase activity http://purl.obolibrary.org/obo/GO_0043841 GO:0043840 biolink:MolecularActivity branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine. MetaCyc:RXN-7708 go-plus.json branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity|branched-chain amino acid aminotransferase|BCAT|branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity http://purl.obolibrary.org/obo/GO_0043840 GO:0043847 biolink:CellularComponent DNA polymerase III, clamp loader chi/psi subcomplex A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB). go-plus.json DNA polymerase III, DnaX complex, chi/psi subcomplex http://purl.obolibrary.org/obo/GO_0043847 GO:0043846 biolink:CellularComponent DNA polymerase III, clamp loader complex A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands. go-plus.json clamp loader complex|DNA polymerase III, DnaX complex|DNA polymerase III, DnaX subcomplex http://purl.obolibrary.org/obo/GO_0043846 UBERON:0005243 biolink:AnatomicalEntity interventricular septum endocardium An endocardium that is part of a interventricular septum [Automatically generated definition]. go-plus.json interventricular septum endocardial tissue|endocardium of interventricular septum http://purl.obolibrary.org/obo/UBERON_0005243 GO:0043849 biolink:MolecularActivity Ras palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins. go-plus.json Ras protein acyltransferase activity|ERF2|palmitoyltransferase ERF2|DHHC cysteine-rich domain-containing protein ERF2 http://purl.obolibrary.org/obo/GO_0043849 GO:0043848 biolink:MolecularActivity obsolete excinuclease cho activity OBSOLETE. Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage. go-plus.json endonuclease cho|uvrc homolog protein|cho http://purl.obolibrary.org/obo/GO_0043848 GO:0043843 biolink:MolecularActivity ADP-specific glucokinase activity Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate. Reactome:R-HSA-5696021|EC:2.7.1.147|RHEA:11460 go-plus.json ADP-dependent glucokinase activity|ADP:D-glucose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0043843 CHEBI:19418 biolink:ChemicalSubstance 3-(acetamidomethylene)-2-(hydroxymethyl)succinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_19418 chebi_ph7_3 GO:0043842 biolink:MolecularActivity Kdo transferase activity Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP. MetaCyc:KDOTRANS2-RXN|EC:2.4.99.15|EC:2.4.99.14|MetaCyc:KDOTRANS-RXN|EC:2.4.99.13|EC:2.4.99.12 go-plus.json WaaA|kdtA|3-deoxy-D-manno-octulosonic-acid transferase activity http://purl.obolibrary.org/obo/GO_0043842 GO:0043845 biolink:CellularComponent DNA polymerase III, proofreading complex A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity. go-plus.json DNA polymerase III, proofreading subcomplex|DNA polymerase III, proof-reading subcomplex|DNA polymerase III, proof-reading complex http://purl.obolibrary.org/obo/GO_0043845 GO:0043844 biolink:MolecularActivity ADP-specific phosphofructokinase activity Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate. RHEA:20105|EC:2.7.1.146 go-plus.json ADP-6-phosphofructokinase activity|ADP-dependent phosphofructokinase activity|ADP:D-fructose-6-phosphate 1-phosphotransferase activity|ADP-Pfk activity http://purl.obolibrary.org/obo/GO_0043844 UBERON:0005249 biolink:AnatomicalEntity metanephric renal pelvis A renal pelvis that is part of a metanephros. go-plus.json metanephros pelvis http://purl.obolibrary.org/obo/UBERON_0005249 UBERON:0005248 biolink:AnatomicalEntity bulbus cordis myocardium A myocardium that is part of a bulbus cordis [Automatically generated definition]. go-plus.json bulbus cordis cardiac muscle http://purl.obolibrary.org/obo/UBERON_0005248 GO:0004249 biolink:MolecularActivity obsolete stromelysin 3 activity OBSOLETE. Was not defined before being made obsolete. go-plus.json matrix metalloproteinase 11|MMP-11|stromelysin 3 activity http://purl.obolibrary.org/obo/GO_0004249 GO:0004246 biolink:MolecularActivity obsolete peptidyl-dipeptidase A activity OBSOLETE. Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II. EC:3.4.15.1|MetaCyc:3.4.15.1-RXN go-plus.json kininase II activity|angiotensin converting enzyme|ACE activity|endothelial cell peptidyl dipeptidase activity|peptidyl dipeptidase-4|angiotensin I-converting enzyme activity|peptidyl dipeptide hydrolase activity|peptidyl dipeptidase I activity|peptidyl-dipeptidase A activity|peptidyl dipeptidase A|peptidase P activity|dipeptide hydrolase|carboxycathepsin activity|dipeptidyl carboxypeptidase I activity|PDH|peptidyldipeptide hydrolase activity|peptidyl-dipeptide hydrolase activity|DCP http://purl.obolibrary.org/obo/GO_0004246 GO:0004245 biolink:MolecularActivity obsolete neprilysin activity OBSOLETE. Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides. go-plus.json enkephalinase activity|CALLA|neutral metallendopeptidase activity|CD10|CALLA glycoprotein|kidney-brush-border neutral peptidase|kidney-brush-border neutral proteinase activity|acute lymphoblastic leukemia antigen|neutral endopeptidase 24.11|neutral endopeptidase activity|endopeptidase-2 activity|neprilysin activity|common acute lymphoblastic leukemia-associated antigens|endopeptidase 24.11|CALLA (common acute lymphoblastic leukemia-associated) antigens|common acute lymphoblastic leukemia antigen|CALLA glycoproteins|CALLA antigen|kidney-brush-border neutral endopeptidase|membrane metalloendopeptidase activity http://purl.obolibrary.org/obo/GO_0004245 GO:0004248 biolink:MolecularActivity obsolete stromelysin 1 activity OBSOLETE. Catalysis of the preferential cleavage where P1', P2' and P3' are hydrophobic residues. go-plus.json proteoglycanase activity|collagen-activating protein|transin activity|neutral proteoglycanase activity|matrix metalloproteinase 3 activity|procollagenase activator|collagenase activating protein|MMP-3|stromelysin|stromelysin 1 activity http://purl.obolibrary.org/obo/GO_0004248 GO:0004247 biolink:MolecularActivity obsolete saccharolysin activity OBSOLETE. Catalysis of the cleavage of Pro-Phe and Ala-Ala bonds. go-plus.json oligopeptidase yscD activity|yeast cysteine proteinase D activity|proteinase yscD activity|saccharolysin activity|saccharomyces cerevisiae proteinase yscD http://purl.obolibrary.org/obo/GO_0004247 GO:0004242 biolink:MolecularActivity obsolete beta-mitochondrial processing peptidase OBSOLETE. (Was not defined before being made obsolete). go-plus.json beta-MPP|beta-mitochondrial processing peptidase http://purl.obolibrary.org/obo/GO_0004242 GO:0004241 biolink:MolecularActivity obsolete alpha-mitochondrial processing peptidase OBSOLETE. (Was not defined before being made obsolete). go-plus.json alpha-MPP|alpha-mitochondrial processing peptidase http://purl.obolibrary.org/obo/GO_0004241 GO:0004244 biolink:MolecularActivity obsolete mitochondrial inner membrane peptidase activity OBSOLETE. Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space. go-plus.json IMP|mitochondrial inner membrane peptidase activity http://purl.obolibrary.org/obo/GO_0004244 GO:0004243 biolink:MolecularActivity obsolete mitochondrial intermediate peptidase activity OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion. go-plus.json mitochondrial intermediate peptidase activity|mitochondrial intermediate precursor-processing proteinase activity|MIP http://purl.obolibrary.org/obo/GO_0004243 GO:0004240 biolink:MolecularActivity obsolete mitochondrial processing peptidase activity OBSOLETE. Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2. go-plus.json alpha-mitochondrial processing peptidase|matrix peptidase|matrix processing proteinase|processing enhancing peptidase activity|mitochondrial protein precursor-processing proteinase activity|processing enhancing peptidase (for one of two subunits)|MPP|matrix processing peptidase|beta-mitochondrial processing peptidase|mitochondrial processing peptidase activity http://purl.obolibrary.org/obo/GO_0004240 GO:0018887 biolink:BiologicalProcess 4-carboxy-4'-sulfoazobenzene metabolic process The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid. UM-BBD_pathwayID:csab go-plus.json 4-carboxy-4'-sulphoazobenzene metabolism|4-carboxy-4'-sulphoazobenzene metabolic process|4-carboxy-4'-sulfoazobenzene metabolism http://purl.obolibrary.org/obo/GO_0018887 GO:0018886 biolink:BiologicalProcess anaerobic carbon tetrachloride metabolic process The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen. UM-BBD_pathwayID:ctc go-plus.json anaerobic carbon tetrachloride metabolism http://purl.obolibrary.org/obo/GO_0018886 GO:0018889 biolink:BiologicalProcess 2-chloro-N-isopropylacetanilide metabolic process The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants. UM-BBD_pathwayID:ppc go-plus.json 2-chloro-N-isopropylacetanilide metabolism|propachlor metabolic process|propachlor metabolism http://purl.obolibrary.org/obo/GO_0018889 GO:0018888 biolink:BiologicalProcess 3-chloroacrylic acid metabolic process The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid. UM-BBD_pathwayID:caa go-plus.json 3-chloroacrylic acid metabolism http://purl.obolibrary.org/obo/GO_0018888 GO:0018883 biolink:BiologicalProcess caprolactam metabolic process The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation. UM-BBD_pathwayID:cap go-plus.json caprolactam metabolism http://purl.obolibrary.org/obo/GO_0018883 GO:0018882 biolink:BiologicalProcess (+)-camphor metabolic process The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed. UM-BBD_pathwayID:cam go-plus.json camphor metabolic process|(+)-camphor metabolism|camphor metabolism http://purl.obolibrary.org/obo/GO_0018882 GO:0018885 biolink:BiologicalProcess carbon tetrachloride metabolic process The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants. UM-BBD_pathwayID:ctc go-plus.json carbon tetrachloride metabolism http://purl.obolibrary.org/obo/GO_0018885 GO:0018884 biolink:BiologicalProcess carbazole metabolic process The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. UM-BBD_pathwayID:car go-plus.json carbazole metabolism|CAR metabolic process|CAR metabolism http://purl.obolibrary.org/obo/GO_0018884 GO:0018881 biolink:BiologicalProcess bromoxynil metabolic process The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants. UM-BBD_pathwayID:box go-plus.json bromoxynil metabolism http://purl.obolibrary.org/obo/GO_0018881 GO:0018880 biolink:BiologicalProcess 4-chlorobiphenyl metabolic process The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation. UM-BBD_pathwayID:cbp go-plus.json 4-chlorobiphenyl metabolism http://purl.obolibrary.org/obo/GO_0018880 GO:0004258 biolink:MolecularActivity obsolete vacuolar carboxypeptidase Y OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity. go-plus.json vacuolar carboxypeptidase Y http://purl.obolibrary.org/obo/GO_0004258 GO:0004253 biolink:MolecularActivity obsolete gamma-renin activity OBSOLETE. Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide. go-plus.json gamma-renin activity http://purl.obolibrary.org/obo/GO_0004253 GO:0004252 biolink:MolecularActivity serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). Reactome:R-HSA-2514772|Reactome:R-HSA-9023626|Reactome:R-HSA-381466|Reactome:R-HSA-6801687|Reactome:R-HSA-3266557|Reactome:R-HSA-140736|Reactome:R-HSA-2471842|Reactome:R-HSA-1566981|Reactome:R-HSA-2471621|Reactome:R-HSA-140664|Reactome:R-HSA-8874204|Reactome:R-HSA-1604690|Reactome:R-HSA-159868|Reactome:R-HSA-158313|Reactome:R-HSA-381461|Reactome:R-HSA-158333|Reactome:R-HSA-158164|Reactome:R-HSA-977615|Reactome:R-HSA-166753|Reactome:R-HSA-5607002|Reactome:R-HSA-9023627|Reactome:R-HSA-166817|Reactome:R-HSA-2172405|Reactome:R-HSA-1592297|Reactome:R-HSA-158750|Reactome:R-HSA-173745|Reactome:R-HSA-158766|Reactome:R-HSA-1474197|Reactome:R-HSA-140777|Reactome:R-HSA-381500|EC:3.4.21.39|Reactome:R-HSA-8874206|Reactome:R-HSA-8874205|Reactome:R-HSA-381798|Reactome:R-HSA-174551|Reactome:R-HSA-9023178|Reactome:R-HSA-1604752|EC:3.4.21.27|Reactome:R-HSA-9686710|EC:3.4.21.38|Reactome:R-HSA-977371|Reactome:R-HSA-1592278|Reactome:R-HSA-158925|Reactome:R-HSA-9668253|Reactome:R-HSA-1592398|Reactome:R-HSA-2534206|Reactome:R-HSA-2482180|Reactome:R-HSA-158311|Reactome:R-HSA-159733|EC:3.4.21.26|EC:3.4.21.48|EC:3.4.21.59|Reactome:R-HSA-9686731|Reactome:R-HSA-9033530|Reactome:R-HSA-9694661|Reactome:R-HSA-2168960|Reactome:R-HSA-9668365|Reactome:R-HSA-1566962|EC:3.4.21.47|EC:3.4.21.36|EC:3.4.21.69|Reactome:R-HSA-8874212|Reactome:R-HSA-140599|Reactome:R-HSA-1604741|Reactome:R-HSA-9694287|Reactome:R-HSA-265301|Reactome:R-HSA-6800299|Reactome:R-HSA-400459|EC:3.4.21.46|EC:3.4.21.35|EC:3.4.21.79|EC:3.4.21.68|Reactome:R-HSA-163798|Reactome:R-HSA-159728|EC:3.4.21.89|Reactome:R-HSA-1592371|Reactome:R-HSA-976743|Reactome:R-HSA-9033520|EC:3.4.21.45|EC:3.4.21.34|EC:3.4.21.78|EC:3.4.21.88|EC:3.4.21.22|Reactome:R-HSA-9033524|Reactome:R-HSA-140700|EC:3.4.21.87|Reactome:R-HSA-166792|Reactome:R-HSA-9033490|Reactome:R-HSA-8849857|EC:3.4.21.21|EC:3.4.21.10|EC:3.4.21.54|EC:3.4.21.43|Reactome:R-HSA-1799329|Reactome:R-HSA-140696|Reactome:R-HSA-163843|Reactome:R-HSA-158419|Reactome:R-HSA-1602466|Reactome:R-HSA-173680|Reactome:R-HSA-381135|EC:3.4.24.34|EC:3.4.19.1|EC:3.4.21.20|EC:3.4.21.53|EC:3.4.21.42|EC:3.4.21.75|Reactome:R-HSA-1602488|EC:3.4.24.7|Reactome:R-HSA-400496|Reactome:R-HSA-140840|Reactome:R-HSA-6807224|Reactome:R-HSA-1912369|EC:3.4.21.41|Reactome:R-HSA-1604368|EC:3.4.21.9|Reactome:R-HSA-2534260|Reactome:R-HSA-3788061|Reactome:R-HSA-5210935|Reactome:R-HSA-8874186|EC:3.4.21.73|EC:3.4.21.62|Reactome:R-HSA-9023633|Reactome:R-HSA-2534160|Reactome:R-HSA-158137|Reactome:R-HSA-158942|Reactome:R-HSA-1181152|Reactome:R-HSA-141026|Reactome:R-HSA-9653249|EC:3.4.21.94|EC:3.4.21.83|Reactome:R-HSA-1566979|EC:3.4.21.61|Reactome:R-HSA-3814820|MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN|Reactome:R-HSA-6800200|Reactome:R-HSA-422051|EC:3.4.21.7|Reactome:R-HSA-400492|EC:3.4.21.93|Reactome:R-HSA-3785684|EC:3.4.21.71|Reactome:R-HSA-1592314|EC:3.4.24.3|EC:3.4.21.6|Reactome:R-HSA-5210912|EC:3.4.21.92|Reactome:R-HSA-159796|Reactome:R-HSA-1592436|Reactome:R-HSA-8865276|Reactome:R-HSA-1592270|Reactome:R-HSA-6800198|EC:3.4.21.5|Reactome:R-HSA-183130|Reactome:R-HSA-9655046|Reactome:R-HSA-159773|Reactome:R-HSA-158744|Reactome:R-HSA-158300|Reactome:R-HSA-5578783|Reactome:R-HSA-9670874|Reactome:R-HSA-5691512|EC:3.4.21.4|Reactome:R-HSA-5591040|Reactome:R-HSA-1592362|EC:3.4.21.102|Reactome:R-HSA-1604731|Reactome:R-HSA-183122|Reactome:R-HSA-8865275|Reactome:R-HSA-9033515|Reactome:R-HSA-158982|Reactome:R-HSA-8855825|Reactome:R-HSA-1602473|Reactome:R-HSA-159771|Reactome:R-HSA-1604722|Reactome:R-HSA-9699007|Reactome:R-HSA-173626|Reactome:R-HSA-1604732|Reactome:R-HSA-9023632|Reactome:R-HSA-2514823|Reactome:R-HSA-1602458|Reactome:R-HSA-8852716|Reactome:R-HSA-114697|Reactome:R-HSA-170844|Reactome:R-HSA-187020|EC:3.4.21.1|Reactome:R-HSA-2168923|Reactome:R-HSA-141040|Reactome:R-HSA-1604712|Reactome:R-HSA-8850831|Reactome:R-HSA-9662786|Reactome:R-HSA-1604360|Reactome:R-HSA-186785|Reactome:R-HSA-140769|Reactome:R-HSA-9023196|Reactome:R-HSA-1602484|Reactome:R-HSA-382061|Reactome:R-HSA-3928657|Reactome:R-HSA-422021|Reactome:R-HSA-171288|Reactome:R-HSA-1604763|Reactome:R-HSA-139893|Reactome:R-HSA-140870|Reactome:R-HSA-1454843|Reactome:R-HSA-1912372|Reactome:R-HSA-9033529|Reactome:R-HSA-381446|Reactome:R-HSA-1655842|Reactome:R-HSA-8849826|Reactome:R-HSA-2214330|Reactome:R-HSA-158747|Reactome:R-HSA-1604359|Reactome:R-HSA-173631|Reactome:R-HSA-140823|Reactome:R-HSA-1592316|Reactome:R-HSA-9673223|Reactome:R-HSA-9033506|EC:3.4.21.-|Reactome:R-HSA-2022411|Reactome:R-HSA-2129357|Reactome:R-HSA-9666383 go-plus.json serine elastase activity|blood coagulation factor activity http://purl.obolibrary.org/obo/GO_0004252 goslim_chembl GO:0004254 biolink:MolecularActivity obsolete acylaminoacyl-peptidase activity OBSOLETE. Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide. go-plus.json acylamino-acid-releasing enzyme activity|acylaminoacyl-peptidase activity|N-formylmethionine (fMet) aminopeptidase activity|alpha-N-acylpeptide hydrolase activity|N-acylpeptide hydrolase activity http://purl.obolibrary.org/obo/GO_0004254 GO:0004251 biolink:MolecularActivity obsolete X-Pro dipeptidase activity OBSOLETE. Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro. EC:3.4.13.9|MetaCyc:3.4.13.9-RXN go-plus.json gamma-peptidase activity|prolidase activity|proline dipeptidase activity|Xaa-Pro dipeptidase activity|X-Pro dipeptidase activity|imidodipeptidase activity|peptidase D http://purl.obolibrary.org/obo/GO_0004251 CHEBI:44485 biolink:ChemicalSubstance N-ethylmaleimide go-plus.json http://purl.obolibrary.org/obo/CHEBI_44485 chebi_ph7_3 GO:0004250 biolink:MolecularActivity obsolete aminopeptidase I activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates. MetaCyc:3.4.11.22-RXN|EC:3.4.11.22 go-plus.json aminopeptidase yscI activity|vacuolar aminopeptidase I activity|aminopeptidase I activity|yeast aminopeptidase I|leucine aminopeptidase IV activity|aminopeptidase III activity http://purl.obolibrary.org/obo/GO_0004250 GO:0018898 biolink:BiologicalProcess 2,4-dichlorobenzoate metabolic process The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). UM-BBD_pathwayID:dcb go-plus.json 2,4-dichlorobenzoate metabolism http://purl.obolibrary.org/obo/GO_0018898 GO:0018897 biolink:BiologicalProcess dibenzothiophene desulfurization The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. UM-BBD_pathwayID:dbt|MetaCyc:PWY-681 go-plus.json dibenzothiophene desulphurization http://purl.obolibrary.org/obo/GO_0018897 GO:0018899 biolink:BiologicalProcess 1,2-dichloroethane metabolic process The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. UM-BBD_pathwayID:dce go-plus.json 1,2-dichloroethane metabolism http://purl.obolibrary.org/obo/GO_0018899 GO:0018894 biolink:BiologicalProcess dibenzo-p-dioxin metabolic process The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern. UM-BBD_pathwayID:dpd go-plus.json oxanthrene metabolic process|oxanthrene metabolism|phenodioxin metabolism|dibenzo-p-dioxin metabolism|phenodioxin metabolic process http://purl.obolibrary.org/obo/GO_0018894 GO:0018893 biolink:BiologicalProcess dibenzofuran metabolic process The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals. UM-BBD_pathwayID:dbf go-plus.json dibenzofuran metabolism http://purl.obolibrary.org/obo/GO_0018893 GO:0018896 biolink:BiologicalProcess dibenzothiophene catabolic process The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. UM-BBD_pathwayID:dbt2 go-plus.json dibenzothiophene catabolism|dibenzothiophene degradation|dibenzothiophene breakdown http://purl.obolibrary.org/obo/GO_0018896 GO:0018895 biolink:BiologicalProcess dibenzothiophene metabolic process The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion. go-plus.json dibenzothiophene metabolism|diphenylene sulfide metabolism|diphenylene sulfide metabolic process http://purl.obolibrary.org/obo/GO_0018895 GO:0018890 biolink:BiologicalProcess cyanamide metabolic process The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism. UM-BBD_pathwayID:cnm go-plus.json cyanamide metabolism http://purl.obolibrary.org/obo/GO_0018890 GO:0018892 biolink:BiologicalProcess cyclohexylsulfamate metabolic process The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide. UM-BBD_pathwayID:chs go-plus.json cyclohexylsulfamate metabolism|cyclohexylsulphamate metabolism|cyclohexylsulphamate metabolic process http://purl.obolibrary.org/obo/GO_0018892 GO:0018891 biolink:BiologicalProcess cyclohexanol metabolic process The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent. UM-BBD_pathwayID:chx go-plus.json cyclohexanol metabolism http://purl.obolibrary.org/obo/GO_0018891 GO:0004228 biolink:MolecularActivity obsolete gelatinase A activity OBSOLETE. Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond. go-plus.json collagenase type IV|gelatinase A activity|type IV collagenase activity|MMP 2|72-kDa gelatinase activity|matrix metalloproteinase 2 activity|3/4 collagenase activity|type IV collagenase/gelatinase activity|type IV collagen metalloproteinase|MMP-2|collagenase IV|72 kDa gelatinase type A|matrix metalloproteinase 5 http://purl.obolibrary.org/obo/GO_0004228 GO:0004229 biolink:MolecularActivity obsolete gelatinase B activity OBSOLETE. Catalysis of the cleavage of gelatin types I and V and collagen types IV and V. go-plus.json collagenase type IV|MMP 9|macrophage gelatinase activity|type V collagenase activity|gelatinase B activity|95 kDa type IV collagenase/gelatinase activity|MMP-9|92-kDa gelatinase activity|type IV collagen metalloproteinase|matrix metalloproteinase 9 activity|92-kDa type IV collagenase activity|gelatinase MMP 9|collagenase IV http://purl.obolibrary.org/obo/GO_0004229 GO:0004226 biolink:MolecularActivity obsolete Gly-X carboxypeptidase activity OBSOLETE. Catalysis of the reaction: peptidyl-Gly-Xaa + H2O = peptidyl-Gly + Xaa. go-plus.json Gly-Xaa carboxypeptidase activity|yeast carboxypeptidase activity|glycine carboxypeptidase activity|Gly-X carboxypeptidase activity|carboxypeptidase S activity|carboxypeptidase a|peptidase alpha http://purl.obolibrary.org/obo/GO_0004226 GO:0004220 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0004220 GO:0004222 biolink:MolecularActivity metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Reactome:R-HSA-1564120|MetaCyc:3.4.24.11-RXN|MetaCyc:3.4.24.22-RXN|Reactome:R-HSA-1592310|MetaCyc:3.4.24.55-RXN|Reactome:R-HSA-194818|Reactome:R-HSA-3828025|EC:3.4.24.37|EC:3.4.24.59|Reactome:R-HSA-2485111|MetaCyc:3.4.24.21-RXN|Reactome:R-HSA-381435|MetaCyc:3.4.24.64-RXN|Reactome:R-HSA-8874201|EC:3.4.24.14|EC:3.4.24.69|Reactome:R-HSA-3791155|Reactome:R-HSA-1299476|Reactome:R-HSA-2534248|Reactome:R-HSA-2533874|EC:3.4.24.24|EC:3.4.24.35|EC:3.4.24.57|Reactome:R-HSA-5250978|Reactome:R-HSA-1251992|Reactome:R-HSA-2473596|Reactome:R-HSA-1474213|Reactome:R-HSA-8867344|Reactome:R-HSA-2534240|EC:3.4.24.23|EC:3.4.24.56|Reactome:R-HSA-8942302|Reactome:R-HSA-8874187|Reactome:R-HSA-8874192|EC:3.4.24.11|EC:3.4.24.22|Reactome:R-HSA-4086205|EC:3.4.24.55|MetaCyc:3.4.24.61-RXN|MetaCyc:3.4.24.72-RXN|Reactome:R-HSA-1564112|Reactome:R-HSA-2473584|Reactome:R-HSA-5250606|Reactome:R-HSA-1564164|Reactome:R-HSA-1474210|Reactome:R-HSA-2022141|EC:3.4.24.21|Reactome:R-HSA-2484882|Reactome:R-HSA-1564179|MetaCyc:3.4.24.71-RXN|EC:3.4.24.64|Reactome:R-HSA-8874194|MetaCyc:3.4.24.70-RXN|Reactome:R-HSA-4224014|Reactome:R-HSA-6784620|Reactome:R-HSA-1458433|Reactome:R-HSA-5250962|Reactome:R-HSA-8874195|Reactome:R-HSA-194808|EC:3.4.24.61|EC:3.4.24.72|Reactome:R-HSA-2533965|EC:3.4.24.71|Reactome:R-HSA-194809|Reactome:R-HSA-194800|Reactome:R-HSA-1564142|Reactome:R-HSA-2485148|Reactome:R-HSA-2168982|EC:3.4.24.70|Reactome:R-HSA-1564169|Reactome:R-HSA-9624272|Reactome:R-HSA-2473594|Reactome:R-HSA-5250892|Reactome:R-HSA-381537|Reactome:R-HSA-8949649|Reactome:R-HSA-264758|Reactome:R-HSA-1474196|Reactome:R-HSA-2514831|Reactome:R-HSA-194793|Reactome:R-HSA-2537499|Reactome:R-HSA-8876868|Reactome:R-HSA-1655851|EC:3.4.24.-|Reactome:R-HSA-8940561|Reactome:R-HSA-8940554|Reactome:R-HSA-8943959|Reactome:R-HSA-3788075|Reactome:R-HSA-2533970|Reactome:R-HSA-381518|Reactome:R-HSA-2168046|Reactome:R-HSA-8949659|Reactome:R-HSA-181567|Reactome:R-HSA-2533950|Reactome:R-HSA-177946|Reactome:R-HSA-5694082|Reactome:R-HSA-2514790|MetaCyc:3.4.24.19-RXN|Reactome:R-HSA-1564117|Reactome:R-HSA-2002440|MetaCyc:3.4.24.18-RXN|Reactome:R-HSA-8877620|MetaCyc:3.4.24.17-RXN|Reactome:R-HSA-1564143|Reactome:R-HSA-2002428|Reactome:R-HSA-194796|Reactome:R-HSA-5362793|Reactome:R-HSA-3791295|Reactome:R-HSA-8949668|Reactome:R-HSA-1564184|MetaCyc:3.4.24.59-RXN|Reactome:R-HSA-3791149|Reactome:R-HSA-3371385|Reactome:R-HSA-2179402|Reactome:R-HSA-1299478|Reactome:R-HSA-2533944|Reactome:R-HSA-1454757|MetaCyc:3.4.24.37-RXN|Reactome:R-HSA-3791319|Reactome:R-HSA-1454822|Reactome:R-HSA-5333671|MetaCyc:3.4.24.69-RXN|EC:3.4.24.19|MetaCyc:3.4.24.14-RXN|Reactome:R-HSA-5228578|Reactome:R-HSA-8940959|MetaCyc:3.4.24.24-RXN|Reactome:R-HSA-8940641|MetaCyc:3.4.24.35-RXN|Reactome:R-HSA-3827958|MetaCyc:3.4.24.57-RXN|EC:3.4.24.18|Reactome:R-HSA-420818|Reactome:R-HSA-1168777|MetaCyc:3.4.24.23-RXN|EC:3.4.24.17|MetaCyc:3.4.24.56-RXN go-plus.json metalloendoproteinase activity|metalloendoprotease activity http://purl.obolibrary.org/obo/GO_0004222 GO:0004221 biolink:MolecularActivity obsolete ubiquitin thiolesterase activity OBSOLETE. Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol. MetaCyc:UBIQUITIN-THIOLESTERASE-RXN|KEGG_REACTION:R02418 go-plus.json ubiquitin-C-terminal-thioester hydrolase activity|ubiquitin carboxy-terminal esterase activity|ubiquitin thioesterase activity|ubiquitin C-terminal hydrolase activity|ubiquitin carboxy-terminal hydrolase activity|ubiquitin thiolesterase activity|ubiquitinyl hydrolase 1 activity http://purl.obolibrary.org/obo/GO_0004221 GO:0018869 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018869 GO:0018868 biolink:BiologicalProcess 2-aminobenzenesulfonate metabolic process The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. UM-BBD_pathwayID:abs go-plus.json 2-aminobenzenesulphonate metabolism|2-aminobenzenesulphonate metabolic process|2-aminobenzenesulfonate metabolism http://purl.obolibrary.org/obo/GO_0018868 CHEBI:138844 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_138844 CHEBI:138843 biolink:ChemicalSubstance 3-oxo bile acid CoA thioester(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138843 chebi_ph7_3 CHEBI:138842 biolink:ChemicalSubstance 3alpha-hydroxy bile acid CoA thioester(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138842 chebi_ph7_3 GO:0018865 biolink:BiologicalProcess acrylonitrile metabolic process The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers. UM-BBD_pathwayID:acr go-plus.json acrylonitrile metabolism http://purl.obolibrary.org/obo/GO_0018865 GO:0018864 biolink:BiologicalProcess acetylene metabolic process The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes. UM-BBD_pathwayID:atl go-plus.json ethyne metabolism|acetylene metabolism|ethyne metabolic process http://purl.obolibrary.org/obo/GO_0018864 GO:0018867 biolink:BiologicalProcess alpha-pinene metabolic process The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor. UM-BBD_pathwayID:apn go-plus.json alpha-pinene metabolism http://purl.obolibrary.org/obo/GO_0018867 GO:0018866 biolink:BiologicalProcess adamantanone metabolic process The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists. UM-BBD_pathwayID:ada go-plus.json adamantanone metabolism http://purl.obolibrary.org/obo/GO_0018866 GO:0018861 biolink:MolecularActivity 4-chlorobenzoate-CoA ligase activity Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway. UM-BBD_reactionID:r0139|KEGG_REACTION:R03932|EC:6.2.1.33|RHEA:23220|MetaCyc:6.2.1.33-RXN go-plus.json 4-chlorobenzoate:CoA ligase activity http://purl.obolibrary.org/obo/GO_0018861 GO:0018860 biolink:MolecularActivity anthranilate-CoA ligase activity Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA. KEGG_REACTION:R00982|UM-BBD_reactionID:r0341|EC:6.2.1.32|MetaCyc:AMINOBENZCOALIG-RXN|RHEA:10828 go-plus.json anthraniloyl coenzyme A synthetase activity|2-aminobenzoate-coenzyme A ligase activity|anthranilate--CoA ligase activity|2-aminobenzoate-CoA ligase activity|2-aminobenzoate coenzyme A ligase activity|anthranilate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0018860 GO:0018863 biolink:MolecularActivity phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene. UM-BBD_reactionID:r0496|EC:3.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0018863 GO:0018862 biolink:MolecularActivity phenylphosphate carboxylase activity Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate. MetaCyc:PHENYLPCARB-RXN|UM-BBD_reactionID:r0157|EC:6.4.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018862 GO:0004239 biolink:MolecularActivity obsolete methionyl aminopeptidase activity OBSOLETE. Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. MetaCyc:3.4.11.18-RXN|EC:3.4.11.18 go-plus.json peptidase M activity|MAP|methionyl aminopeptidase activity|L-methionine aminopeptidase activity|methionine aminopeptidase activity http://purl.obolibrary.org/obo/GO_0004239 GO:0004238 biolink:MolecularActivity obsolete meprin A activity OBSOLETE. Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues. go-plus.json endopeptidase-2 activity|N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase activity|meprin A activity|meprin-a|PPH|PABA-peptide hydrolase activity|meprin http://purl.obolibrary.org/obo/GO_0004238 GO:0004235 biolink:MolecularActivity obsolete matrilysin activity OBSOLETE. Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I). go-plus.json matrin activity|metalloproteinase pump-1|MMP|PUMP-1 activity|uterine metalloendopeptidase activity|PUMP-1 proteinase activity|PUMP|MMP 7|matrilysin activity|MMP-7|putative metalloproteinase activity|putative (or punctuated) metalloproteinase-1 activity|matrix metalloproteinase pump 1|matrix metalloproteinase 7 activity http://purl.obolibrary.org/obo/GO_0004235 GO:0004234 biolink:MolecularActivity obsolete macrophage elastase activity OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. MetaCyc:3.4.24.65-RXN|EC:3.4.24.65 go-plus.json human macrophage metalloelastase (HME)|macrophage elastase activity|metalloesterase activity|metalloelastase activity|MMP-12|matrix metalloproteinase 12 activity http://purl.obolibrary.org/obo/GO_0004234 GO:0004237 biolink:MolecularActivity obsolete membrane dipeptidase activity OBSOLETE. Catalysis of the hydrolysis of dipeptides. MetaCyc:3.4.13.19-RXN|EC:3.4.13.19 go-plus.json dipeptidyl hydrolase activity|microsomal dipeptidase activity|dehydropeptidase I (DPH I)|dipeptide hydrolase|glycosyl-phosphatidylinositol-anchored renal dipeptidase activity|MDP|renal dipeptidase activity|membrane dipeptidase activity|dehydropeptidase I activity|nonspecific dipeptidase activity|DPH I activity|aminodipeptidase activity http://purl.obolibrary.org/obo/GO_0004237 GO:0004231 biolink:MolecularActivity obsolete insulysin activity OBSOLETE. Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins. go-plus.json insulin-degrading neutral proteinase activity|insulin-glucagon protease activity|insulysin activity|insulin-specific protease activity|IDE|insulin proteinase activity|insulinase activity|insulin protease activity|insulin-degrading enzyme activity|metalloinsulinase activity http://purl.obolibrary.org/obo/GO_0004231 CHEBI:6809 biolink:ChemicalSubstance methamphetamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_6809 GO:0004230 biolink:MolecularActivity obsolete glutamyl aminopeptidase activity OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide. MetaCyc:3.4.11.7-RXN|EC:3.4.11.7 go-plus.json glutamyl aminopeptidase activity|aspartate aminopeptidase activity|L-aspartate aminopeptidase activity|angiotensinase A|angiotensinase A2|antigen BP-1/6C3 of mouse B lymphocytes|membrane aminopeptidase II|glutamyl peptidase activity|Ca2+-activated glutamate aminopeptidase activity|aminopeptidase A http://purl.obolibrary.org/obo/GO_0004230 GO:0004232 biolink:MolecularActivity obsolete interstitial collagenase activity OBSOLETE. Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue. go-plus.json MMP-1|matrix metalloproteinase 1|interstitial collagenase activity|vertebrate collagenase activity http://purl.obolibrary.org/obo/GO_0004232 CHEBI:6801 biolink:ChemicalSubstance metformin go-plus.json http://purl.obolibrary.org/obo/CHEBI_6801 GO:0018879 biolink:BiologicalProcess biphenyl metabolic process The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs). UM-BBD_pathwayID:bph go-plus.json xenene metabolic process|xenene metabolism|biphenyl metabolism http://purl.obolibrary.org/obo/GO_0018879 GO:0018876 biolink:BiologicalProcess benzonitrile metabolic process The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin. UM-BBD_pathwayID:bzn go-plus.json benzonitrile metabolism http://purl.obolibrary.org/obo/GO_0018876 GO:0018875 biolink:BiologicalProcess anaerobic benzoate metabolic process The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen. UM-BBD_pathwayID:benz|MetaCyc:CENTBENZCOA-PWY go-plus.json anaerobic benzoate metabolism http://purl.obolibrary.org/obo/GO_0018875 GO:0018878 biolink:BiologicalProcess aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen. go-plus.json aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism http://purl.obolibrary.org/obo/GO_0018878 GO:0018877 biolink:BiologicalProcess beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health. UM-BBD_pathwayID:hch go-plus.json beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism http://purl.obolibrary.org/obo/GO_0018877 GO:0018872 biolink:BiologicalProcess arsonoacetate metabolic process The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides. UM-BBD_pathwayID:ara go-plus.json arsonoacetate metabolism http://purl.obolibrary.org/obo/GO_0018872 GO:0018871 biolink:BiologicalProcess 1-aminocyclopropane-1-carboxylate metabolic process The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. UM-BBD_pathwayID:acp go-plus.json 1-aminocyclopropane-1-carboxylate metabolism|ACP metabolism|ACP metabolic process http://purl.obolibrary.org/obo/GO_0018871 GO:0018874 biolink:BiologicalProcess benzoate metabolic process The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid. UM-BBD_pathwayID:benz2|MetaCyc:P321-PWY go-plus.json benzoate metabolism http://purl.obolibrary.org/obo/GO_0018874 GO:0018873 biolink:BiologicalProcess atrazine metabolic process The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide. UM-BBD_pathwayID:atr go-plus.json atrazine metabolism http://purl.obolibrary.org/obo/GO_0018873 GO:0018870 biolink:BiologicalProcess anaerobic 2-aminobenzoate metabolic process The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen. UM-BBD_pathwayID:abz go-plus.json anaerobic 2-aminobenzoate metabolism http://purl.obolibrary.org/obo/GO_0018870 GO:0004206 biolink:MolecularActivity obsolete caspase-10 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-10 activity http://purl.obolibrary.org/obo/GO_0004206 GO:0004205 biolink:MolecularActivity obsolete caspase-8 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-8 activity http://purl.obolibrary.org/obo/GO_0004205 GO:0004208 biolink:MolecularActivity obsolete caspase-3 activity OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase family C14 and they appear to function in the inactivation of proteins involved in cellular repair and homeostasis during the effector stage of apoptosis. go-plus.json caspase-3 activity http://purl.obolibrary.org/obo/GO_0004208 CHEBI:20485 biolink:ChemicalSubstance 4-pyridones go-plus.json http://purl.obolibrary.org/obo/CHEBI_20485 GO:0004207 biolink:MolecularActivity obsolete effector caspase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json effector caspase activity http://purl.obolibrary.org/obo/GO_0004207 GO:0004202 biolink:MolecularActivity obsolete caspase-2 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-2 activity http://purl.obolibrary.org/obo/GO_0004202 GO:0004201 biolink:MolecularActivity obsolete caspase-1 activity OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec. go-plus.json ICE|caspase-1 activity http://purl.obolibrary.org/obo/GO_0004201 GO:0004204 biolink:MolecularActivity obsolete caspase-5 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-5 activity http://purl.obolibrary.org/obo/GO_0004204 GO:0004203 biolink:MolecularActivity obsolete caspase-4 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-4 activity http://purl.obolibrary.org/obo/GO_0004203 GO:0004200 biolink:MolecularActivity obsolete signaling (initiator) caspase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json signaling (initiator) caspase activity|signalling (initiator) caspase activity http://purl.obolibrary.org/obo/GO_0004200 GO:0018847 biolink:MolecularActivity alpha-pinene lyase activity Catalysis of the reaction: alpha-pinene = limonene. UM-BBD_reactionID:r0712|EC:5.5.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018847 GO:0018846 biolink:MolecularActivity styrene-oxide isomerase activity Catalysis of the reaction: styrene oxide = phenylacetaldehyde. EC:5.3.99.7|RHEA:21604|KEGG_REACTION:R02615|MetaCyc:STYRENE-OXIDE-ISOMERASE-RXN|UM-BBD_reactionID:r0034 go-plus.json styrene-oxide isomerase (epoxide-cleaving)|SOI activity|styrene oxide isomerase activity http://purl.obolibrary.org/obo/GO_0018846 GO:0018849 biolink:MolecularActivity muconate cycloisomerase activity Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate. UM-BBD_enzymeID:e0133|MetaCyc:MUCONATE-CYCLOISOMERASE-RXN|RHEA:30031|EC:5.5.1.1 go-plus.json muconate lactonizing enzyme activity|muconate cycloisomerase I activity|cis,cis-muconate-lactonizing enzyme|muconate lactonizing enzyme I activity|cis,cis-muconate cycloisomerase activity http://purl.obolibrary.org/obo/GO_0018849 GO:0018848 biolink:MolecularActivity pinocarveol isomerase activity Catalysis of the reaction: pinocarveol = carveol. UM-BBD_reactionID:r0715|EC:5.5.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018848 GO:0018843 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018843 GO:0018842 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018842 GO:0018845 biolink:MolecularActivity 2-hydroxychromene-2-carboxylate isomerase activity Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate. UM-BBD_reactionID:r0337|KEGG_REACTION:R05137|RHEA:27401|EC:5.99.1.4|MetaCyc:RXNN-386 go-plus.json http://purl.obolibrary.org/obo/GO_0018845 GO:0018844 biolink:MolecularActivity 2-hydroxytetrahydrofuran isomerase activity Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde. UM-BBD_reactionID:r0019|EC:5.3.99.- go-plus.json http://purl.obolibrary.org/obo/GO_0018844 GO:0018841 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018841 GO:0018840 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018840 GO:0004209 biolink:MolecularActivity obsolete caspase-6 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-6 activity http://purl.obolibrary.org/obo/GO_0004209 GO:0004217 biolink:MolecularActivity obsolete cathepsin L activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity. go-plus.json cathepsin L activity|Aldrichina grahami cysteine proteinase http://purl.obolibrary.org/obo/GO_0004217 GO:0004216 biolink:MolecularActivity obsolete cathepsin K activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg. go-plus.json cathepsin O2 activity|cathepsin O activity|cathepsin K activity|cathepsin X activity http://purl.obolibrary.org/obo/GO_0004216 GO:0004219 biolink:MolecularActivity obsolete pyroglutamyl-peptidase I activity OBSOLETE. Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide. MetaCyc:PYROGLUTAMYL-PEPTIDASE-I-RXN|EC:3.4.19.3 go-plus.json L-pyrrolidonecarboxylate peptidase activity|pyrrolidone carboxyl peptidase activity|pyroglutamate aminopeptidase activity|PYRase activity|pyrrolidone-carboxyl peptidase activity|L-pyroglutamyl peptide hydrolase activity|pyrrolidonyl peptidase activity|5-oxoprolyl-peptidase activity|pyroglutamyl-peptidase I activity|pyroglutamyl aminopeptidase activity|pyrrolidone-carboxylate peptidase activity|pyrrolidonecarboxylyl peptidase activity|pyroglutamidase activity http://purl.obolibrary.org/obo/GO_0004219 GO:0004218 biolink:MolecularActivity obsolete cathepsin S activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds. go-plus.json cathepsin S activity http://purl.obolibrary.org/obo/GO_0004218 GO:0004213 biolink:MolecularActivity obsolete cathepsin B activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. go-plus.json cathepsin B1 activity|cathepsin B activity|cathepsin II http://purl.obolibrary.org/obo/GO_0004213 GO:0004212 biolink:MolecularActivity obsolete lysosomal cysteine-type endopeptidase OBSOLETE. (Was not defined before being made obsolete). go-plus.json lysosomal cysteine-type endopeptidase http://purl.obolibrary.org/obo/GO_0004212 GO:0004215 biolink:MolecularActivity obsolete cathepsin H activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase. go-plus.json cathepsin BA activity|cathepsin Ba|cathepsin H activity|benzoylarginine-naphthylamide (BANA) hydrolase activity|aleurain activity|cathepsin B3 activity|N-benzoylarginine-beta-naphthylamide hydrolase activity http://purl.obolibrary.org/obo/GO_0004215 GO:0004214 biolink:MolecularActivity obsolete dipeptidyl-peptidase I activity OBSOLETE. Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro. EC:3.4.14.1|MetaCyc:3.4.14.1-RXN go-plus.json dipeptide arylamidase I|DAP I|dipeptidyl transferase activity|dipeptidyl-peptidase I activity|cathepsin C activity|dipeptidyl aminopeptidase I activity|cathepsin J activity http://purl.obolibrary.org/obo/GO_0004214 GO:0004211 biolink:MolecularActivity obsolete caspase-9 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-9 activity http://purl.obolibrary.org/obo/GO_0004211 GO:0004210 biolink:MolecularActivity obsolete caspase-7 activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json caspase-7 activity http://purl.obolibrary.org/obo/GO_0004210 GO:0018858 biolink:MolecularActivity benzoate-CoA ligase activity Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate. MetaCyc:BENZOATE--COA-LIGASE-RXN|EC:6.2.1.25|UM-BBD_reactionID:r0189|KEGG_REACTION:R01422|RHEA:10132 go-plus.json benzoate:CoA ligase (AMP-forming)|benzoyl CoA synthetase (AMP forming)|benzoyl-coenzyme A synthetase activity|benzoate-coenzyme A ligase activity http://purl.obolibrary.org/obo/GO_0018858 GO:0018857 biolink:MolecularActivity 2,4-dichlorobenzoate-CoA ligase activity Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA. UM-BBD_reactionID:r0137 go-plus.json http://purl.obolibrary.org/obo/GO_0018857 GO:0018859 biolink:MolecularActivity 4-hydroxybenzoate-CoA ligase activity Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA. MetaCyc:4-HYDROXYBENZOATE--COA-LIGASE-RXN|EC:6.2.1.27|UM-BBD_reactionID:r0156|RHEA:23116|KEGG_REACTION:R01300 go-plus.json 4-hydroxybenzoyl-CoA ligase activity|4-hydroxybenzoate:CoA ligase (AMP-forming)|4-hydroxybenzoyl coenzyme A synthetase activity|4-hydroxybenzoate-CoA synthetase activity|4-hydroxybenzoate-coenzyme A ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0018859 GO:0018854 biolink:MolecularActivity 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA. UM-BBD_reactionID:r0737 go-plus.json http://purl.obolibrary.org/obo/GO_0018854 GO:0018853 biolink:MolecularActivity obsolete perillyl-CoA synthetase activity OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA. EC:6.2.1.-|UM-BBD_reactionID:r0731 go-plus.json perillyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0018853 GO:0018856 biolink:MolecularActivity benzoyl acetate-CoA ligase activity Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA. KEGG_REACTION:R05452|UM-BBD_reactionID:r0242|SABIO-RK:5058 go-plus.json http://purl.obolibrary.org/obo/GO_0018856 GO:0018855 biolink:MolecularActivity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA. UM-BBD_reactionID:r0429|RHEA:33419|EC:6.2.1.38 go-plus.json http://purl.obolibrary.org/obo/GO_0018855 GO:0018850 biolink:MolecularActivity chloromuconate cycloisomerase activity Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate. UM-BBD_enzymeID:e0065|EC:5.5.1.7|RHEA:11032 go-plus.json muconate cycloisomerase II activity|2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing) http://purl.obolibrary.org/obo/GO_0018850 GO:0018852 biolink:MolecularActivity dichloromuconate cycloisomerase activity Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate. MetaCyc:DICHLOROMUCONATE-CYCLOISOMERASE-RXN|UM-BBD_reactionID:r0277|EC:5.5.1.11|RHEA:17437 go-plus.json 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing) http://purl.obolibrary.org/obo/GO_0018852 GO:0018851 biolink:MolecularActivity alpha-pinene-oxide decyclase activity Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal. RHEA:16693|KEGG_REACTION:R04040|MetaCyc:ALPHA-PINENE-OXIDE-DECYCLASE-RXN|UM-BBD_reactionID:r0743|EC:5.5.1.10 go-plus.json alpha-pinene-oxide lyase (decyclizing)|alpha-pinene oxide lyase activity http://purl.obolibrary.org/obo/GO_0018851 CHEBI:19475 biolink:ChemicalSubstance 2-aminopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19475 CHEBI:368997 biolink:ChemicalSubstance N-benzyloxycarbonylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_368997 chebi_ph7_3 CHEBI:138809 biolink:ChemicalSubstance (3R)-3-hydroxy-4-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138809 chebi_ph7_3 CHEBI:138808 biolink:ChemicalSubstance CDP-4-dehydro-6-deoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138808 chebi_ph7_3 CHEBI:138807 biolink:ChemicalSubstance ent-copal-8-ol diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138807 GO:0018829 biolink:MolecularActivity 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU. UM-BBD_reactionID:r0513|EC:4.5.1.- go-plus.json DDD dehydrochlorinase activity http://purl.obolibrary.org/obo/GO_0018829 GO:0018828 biolink:MolecularActivity halohydrin hydrogen-halide-lyase A activity Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane. UM-BBD_enzymeID:e0048 go-plus.json http://purl.obolibrary.org/obo/GO_0018828 GO:0018825 biolink:MolecularActivity triethanolamine lyase activity Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde. UM-BBD_enzymeID:e0421 go-plus.json http://purl.obolibrary.org/obo/GO_0018825 CHEBI:138801 biolink:ChemicalSubstance D-tagatopyranose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138801 GO:0018824 biolink:MolecularActivity (hydroxyamino)benzene mutase activity Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol. UM-BBD_reactionID:r0304|MetaCyc:5.4.4.1-RXN|RHEA:19245 go-plus.json hydroxylaminobenzene mutase activity|HAB mutase activity|hydroxylaminobenzene hydroxymutase activity|(hydroxyamino)benzene hydroxymutase activity http://purl.obolibrary.org/obo/GO_0018824 GO:0018827 biolink:MolecularActivity 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU. UM-BBD_reactionID:r0515|EC:4.5.1.- go-plus.json DDMS dehydrochlorinase activity http://purl.obolibrary.org/obo/GO_0018827 GO:0018826 biolink:MolecularActivity methionine gamma-lyase activity Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate. UM-BBD_reactionID:r0432|RHEA:23800|EC:4.4.1.11|MetaCyc:METHIONINE-GAMMA-LYASE-RXN go-plus.json methioninase activity|L-methioninase activity|L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)|methionine dethiomethylase activity|L-methionine methanethiol-lyase (deaminating)|L-methionine gamma-lyase activity|methionine lyase activity http://purl.obolibrary.org/obo/GO_0018826 GO:0018821 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018821 GO:0018820 biolink:MolecularActivity cyanamide hydratase activity Catalysis of the reaction: urea = cyanamide + H(2)O. MetaCyc:CYANAMIDE-HYDRATASE-RXN|UM-BBD_reactionID:r0668|KEGG_REACTION:R00778|EC:4.2.1.69|RHEA:23056 go-plus.json urea hydro-lyase activity|urea hydro-lyase (cyanamide-forming) http://purl.obolibrary.org/obo/GO_0018820 GO:0018823 biolink:MolecularActivity cyclohexa-1,5-dienecarbonyl-CoA hydratase activity Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA. RHEA:21856|UM-BBD_reactionID:r0203|KEGG_REACTION:R05597|MetaCyc:4.2.1.100-RXN|EC:4.2.1.100 go-plus.json dienoyl-CoA hydratase activity|cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity|6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)|cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity|cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity|cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity http://purl.obolibrary.org/obo/GO_0018823 CHEBI:138803 biolink:ChemicalSubstance archaeosine 5'-phosphate zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138803 chebi_ph7_3 GO:0018822 biolink:MolecularActivity nitrile hydratase activity Catalysis of the reaction: an aliphatic amide = a nitrile + H2O. UM-BBD_enzymeID:e0067|EC:4.2.1.84|RHEA:12673|MetaCyc:NITRILE-HYDRATASE-RXN go-plus.json H-NHase activity|L-NHase activity|NHase activity|aliphatic-amide hydro-lyase (nitrile-forming)|acrylonitrile hydratase activity|3-cyanopyridine hydratase activity|nitrile hydro-lyase activity|aliphatic nitrile hydratase activity http://purl.obolibrary.org/obo/GO_0018822 CHEBI:20476 biolink:ChemicalSubstance 4-sulfonatobenzoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_20476 chebi_ph7_3 CHEBI:44423 biolink:ChemicalSubstance hydroxyurea go-plus.json http://purl.obolibrary.org/obo/CHEBI_44423 chebi_ph7_3 GO:0018839 biolink:MolecularActivity cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate. UM-BBD_reactionID:r0163|EC:5.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018839 GO:0018836 biolink:MolecularActivity alkylmercury lyase activity Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+. RHEA:18777|MetaCyc:ALKYLMERCURY-LYASE-RXN|EC:4.99.1.2|UM-BBD_enzymeID:e0055 go-plus.json organomercurial lyase activity|alkylmercury mercuric-lyase activity|organomercury lyase activity|alkylmercury mercuric-lyase (alkane-forming) http://purl.obolibrary.org/obo/GO_0018836 GO:0018835 biolink:MolecularActivity carbon phosphorus lyase activity Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate). EC:4.7.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018835 GO:0018838 biolink:MolecularActivity mandelate racemase activity Catalysis of the reaction: (S)-mandelate = (R)-mandelate. UM-BBD_reactionID:r0091|EC:5.1.2.2|MetaCyc:MANDELATE-RACEMASE-RXN|RHEA:13945 go-plus.json http://purl.obolibrary.org/obo/GO_0018838 GO:0018837 biolink:MolecularActivity 2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate. UM-BBD_reactionID:r0502 go-plus.json http://purl.obolibrary.org/obo/GO_0018837 GO:0018832 biolink:MolecularActivity halohydrin hydrogen-halide-lyase B activity Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane. UM-BBD_enzymeID:e0050 go-plus.json http://purl.obolibrary.org/obo/GO_0018832 GO:0018831 biolink:MolecularActivity 5-chloro-1,2,4-trihydroxybenzene dechlorinase activity Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone. EC:4.5.1.-|UM-BBD_reactionID:r0666 go-plus.json http://purl.obolibrary.org/obo/GO_0018831 GO:0018834 biolink:MolecularActivity dichloromethane dehalogenase activity Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+). EC:4.5.1.3|RHEA:15397|MetaCyc:DICHLOROMETHANE-DEHALOGENASE-RXN|KEGG_REACTION:R00603|UM-BBD_reactionID:r0188 go-plus.json dichloromethane chloride-lyase (chloride-hydrolysing)|dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming) http://purl.obolibrary.org/obo/GO_0018834 GO:0018833 biolink:MolecularActivity DDT-dehydrochlorinase activity Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+). RHEA:19217|EC:4.5.1.1|MetaCyc:DDT-DEHYDROCHLORINASE-RXN|UM-BBD_reactionID:r0439|KEGG_REACTION:R04522 go-plus.json DDT dehydrochlorinase activity|DDT-ase activity|DDTase activity|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity|DDT-as|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming] http://purl.obolibrary.org/obo/GO_0018833 CHEBI:20479 biolink:ChemicalSubstance (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20479 chebi_ph7_3 GO:0018830 biolink:MolecularActivity gamma-hexachlorocyclohexane dehydrochlorinase activity Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene. EC:4.5.1.-|UM-BBD_enzymeID:e0359 go-plus.json http://purl.obolibrary.org/obo/GO_0018830 SO:0000165 biolink:SequenceFeature enhancer A cis-acting sequence that increases the utilization of (some) eukaryotic promoters, and can function in either orientation and in any location (upstream or downstream) relative to the promoter. http://en.wikipedia.org/wiki/Enhancer_(genetics) go-plus.json INSDC_qualifier:enhancer|INSDC_feature:regulatory http://purl.obolibrary.org/obo/SO_0000165 SOFA UBERON:0001309 biolink:AnatomicalEntity internal iliac artery The internal iliac artery (formerly known as the hypogastric artery) is the main artery of the pelvis. [WP,unvetted]. go-plus.json hypogastric artery|arteria iliaca interna http://purl.obolibrary.org/obo/UBERON_0001309 UBERON:0001308 biolink:AnatomicalEntity external iliac artery The external iliac artery is a large artery in the pelvic region that carries blood to the lower limb. The external iliac artery is a paired artery, meaning there is one on each side of the body: a right external iliac artery and left external iliac artery. The external iliac artery is accompanied by the external iliac vein, which is located posterior to the artery. [WP,unvetted]. go-plus.json arteria iliaca externa http://purl.obolibrary.org/obo/UBERON_0001308 CHEBI:73774 biolink:ChemicalSubstance enterobacterial common antigen go-plus.json http://purl.obolibrary.org/obo/CHEBI_73774 SO:0000167 biolink:SequenceFeature promoter A regulatory_region composed of the TSS(s) and binding sites for TF_complexes of the core transcription machinery. A region (DNA) to which RNA polymerase binds, to begin transcription. http://en.wikipedia.org/wiki/Promoter go-plus.json INSDC_qualifier:promoter|promoter sequence|INSDC_feature:regulatory http://purl.obolibrary.org/obo/SO_0000167 SOFA CHEBI:73777 biolink:ChemicalSubstance N-acetyl-D-mannosaminouronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73777 CHEBI:73776 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_73776 chebi_ph7_3 UBERON:0001305 biolink:AnatomicalEntity ovarian follicle A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified]. go-plus.json follicle of ovary|ovary follicle|follicle of ovary viewed macroscopically|egg follicle|folliculi ovarici primarii|folliculi ovarici vesiculosi http://purl.obolibrary.org/obo/UBERON_0001305 CHEBI:73779 biolink:ChemicalSubstance Gly-Pro zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73779 chebi_ph7_3 UBERON:0001304 biolink:AnatomicalEntity germinal epithelium of ovary layer of simple cuboidal cells covering surface of ovary[WP]. go-plus.json ovary germinal epithelium|surface epithelium of ovary|ovarian surface epithelium|germinal epithelium (female)|epithelium superficiale (ovarium)|ovary surface epithelium|female coelomic epithelium http://purl.obolibrary.org/obo/UBERON_0001304 UBERON:0001307 biolink:AnatomicalEntity capsule of ovary A capsule that surrounds a female gonad. go-plus.json ovary capsule|ovarian capsule http://purl.obolibrary.org/obo/UBERON_0001307 UBERON:0001306 biolink:AnatomicalEntity cumulus oophorus A cluster of cells that project into the cavity of the mature ovarian follicle. It is released with the embedded oocyte during ovulation. In order for fertilization to occur this layer must be penetrated by the spermatocyte. [WP,modified]. go-plus.json cumulus ovaricus|discus proligerus|ovarian cumulus http://purl.obolibrary.org/obo/UBERON_0001306 CHEBI:58133 biolink:ChemicalSubstance 3-(imidazol-5-yl)pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58133 chebi_ph7_3 CHEBI:58132 biolink:ChemicalSubstance 3-chloro-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58132 chebi_ph7_3 CHEBI:58131 biolink:ChemicalSubstance 2-methylpropanoyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58131 chebi_ph7_3 CHEBI:58130 biolink:ChemicalSubstance myo-inositol hexakisphosphate(12-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58130 chebi_ph7_3 UBERON:0001312 biolink:AnatomicalEntity superior vesical artery An artery that supplies blood to the upper urinary bladder. go-plus.json arteriae vesicales superiores|arteria vesicali superior|arteria vesicalis superior http://purl.obolibrary.org/obo/UBERON_0001312 CHEBI:58139 biolink:ChemicalSubstance 3-hydroxy-cis,cis-muconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58139 chebi_ph7_3 CHEBI:58138 biolink:ChemicalSubstance N-caffeoylputrescinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58138 chebi_ph7_3 CHEBI:73771 biolink:ChemicalSubstance Ala-His go-plus.json http://purl.obolibrary.org/obo/CHEBI_73771 CHEBI:34162 biolink:ChemicalSubstance 16(R)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34162 CHEBI:73770 biolink:ChemicalSubstance Ala-Leu go-plus.json http://purl.obolibrary.org/obo/CHEBI_73770 CHEBI:58137 biolink:ChemicalSubstance 3,4-dihydroxyphthalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58137 chebi_ph7_3 UBERON:0001310 biolink:AnatomicalEntity umbilical artery The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]. go-plus.json a. umbilicalis http://purl.obolibrary.org/obo/UBERON_0001310 CHEBI:58136 biolink:ChemicalSubstance 2,5-dioxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58136 chebi_ph7_3 CHEBI:58135 biolink:ChemicalSubstance 2-(hydroxymethyl)-4-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58135 chebi_ph7_3 CHEBI:73772 biolink:ChemicalSubstance K antigen go-plus.json http://purl.obolibrary.org/obo/CHEBI_73772 CHEBI:73786 biolink:ChemicalSubstance Ala-Gly zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73786 chebi_ph7_3 CHEBI:73785 biolink:ChemicalSubstance 4-acetamido-4,6-dideoxy-D-galactosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_73785 chebi_ph7_3 CHEBI:73788 biolink:ChemicalSubstance Ala-Gln go-plus.json http://purl.obolibrary.org/obo/CHEBI_73788 CHEBI:83103 biolink:ChemicalSubstance N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83103 CHEBI:58123 biolink:ChemicalSubstance (2S)-2-hydroxy monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58123 chebi_ph7_3 CHEBI:58122 biolink:ChemicalSubstance N(6)-acetyl-N(6)-hydroxy-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58122 chebi_ph7_3 CHEBI:83100 biolink:ChemicalSubstance N(6)-[(R)-dihydrolipoyl]-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83100 chebi_ph7_3 CHEBI:58121 biolink:ChemicalSubstance D-ribulose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58121 chebi_ph7_3 CHEBI:143816 biolink:ChemicalSubstance alpha-D-glucosaminyl-(1->6)-(phosphatidyl)-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143816 chebi_ph7_3 CHEBI:143815 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-(1->6)-(phosphatidyl)-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143815 chebi_ph7_3 CHEBI:143813 biolink:ChemicalSubstance 1-radyl,2-acyl-sn-glycero-3-phospho-(1D-myo-2-acyl-inositol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143813 chebi_ph7_3 UBERON:0001301 biolink:AnatomicalEntity epididymis the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens go-plus.json http://purl.obolibrary.org/obo/UBERON_0001301 UBERON:0001303 biolink:AnatomicalEntity left uterine tube A fallopian tube that is part of a left side of organism [Automatically generated definition]. go-plus.json left fallopian tube|left oviduct http://purl.obolibrary.org/obo/UBERON_0001303 CHEBI:58129 biolink:ChemicalSubstance cis-caffeate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58129 chebi_ph7_3 CHEBI:34172 biolink:ChemicalSubstance 16alpha-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_34172 chebi_ph7_3 UBERON:0001302 biolink:AnatomicalEntity right uterine tube A fallopian tube that is part of a right side of organism [Automatically generated definition]. go-plus.json right oviduct|right fallopian tube http://purl.obolibrary.org/obo/UBERON_0001302 CHEBI:58128 biolink:ChemicalSubstance N(5)-ethyl-L-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58128 chebi_ph7_3 CHEBI:58127 biolink:ChemicalSubstance GDP-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58127 chebi_ph7_3 CHEBI:58126 biolink:ChemicalSubstance porphobilinogen(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58126 chebi_ph7_3 CHEBI:73781 biolink:ChemicalSubstance N-acetyl-D-mannosaminouronosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_73781 CHEBI:73784 biolink:ChemicalSubstance Gly-Glu(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73784 chebi_ph7_3 CHEBI:58125 biolink:ChemicalSubstance 3-hydroxy-L-kynurenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58125 chebi_ph7_3 CHEBI:73783 biolink:ChemicalSubstance 4-acetamido-4,6-dideoxy-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_73783 chebi_ph7_3 CHEBI:143819 biolink:ChemicalSubstance C-terminal amino acid residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143819 chebi_ph7_3 CHEBI:58124 biolink:ChemicalSubstance isovitexin 2''-O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58124 chebi_ph7_3 CHEBI:48796 biolink:ChemicalSubstance iron-sulfur-molybdenum cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_48796 SO:0000188 biolink:SequenceFeature intron A region of a primary transcript that is transcribed, but removed from within the transcript by splicing together the sequences (exons) on either side of it. http://en.wikipedia.org/wiki/Intron go-plus.json INSDC_feature:intron http://purl.obolibrary.org/obo/SO_0000188 SOFA CHEBI:58112 biolink:ChemicalSubstance cetraxate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58112 chebi_ph7_3 CHEBI:34145 biolink:ChemicalSubstance 12(R)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34145 CHEBI:83111 biolink:ChemicalSubstance N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83111 chebi_ph7_3 CHEBI:34144 biolink:ChemicalSubstance 12(R)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34144 CHEBI:58111 biolink:ChemicalSubstance N(5)-acyl-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58111 chebi_ph7_3 CHEBI:58110 biolink:ChemicalSubstance CDP-3,6-dideoxy-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58110 chebi_ph7_3 CHEBI:34146 biolink:ChemicalSubstance 12(S)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34146 CHEBI:58119 biolink:ChemicalSubstance N(4)-phosphonatoagmatine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58119 chebi_ph7_3 CHEBI:58118 biolink:ChemicalSubstance L-rhamnonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58118 chebi_ph7_3 CHEBI:58117 biolink:ChemicalSubstance (S)-2-acetamido-6-oxopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58117 chebi_ph7_3 CHEBI:58116 biolink:ChemicalSubstance 5-methyl-5,6,7,8-tetrahydromethanopterin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58116 chebi_ph7_3 CHEBI:58115 biolink:ChemicalSubstance guanosine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58115 chebi_ph7_3 CHEBI:73792 biolink:ChemicalSubstance 1-arachidonoyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73792 CHEBI:58114 biolink:ChemicalSubstance 2-carboxylato-cis,cis-muconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58114 chebi_ph7_3 CHEBI:58113 biolink:ChemicalSubstance L-2-ammoniohexano-6-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_58113 chebi_ph7_3 SO:0000170 biolink:SequenceFeature RNApol_II_promoter A DNA sequence in eukaryotic DNA to which RNA polymerase II binds, to begin transcription. go-plus.json pol II promoter|RNApol II promoter|polymerase II promoter|RNA polymerase B promoter http://purl.obolibrary.org/obo/SO_0000170 CHEBI:58101 biolink:ChemicalSubstance N(1)-acetylsperminium(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58101 chebi_ph7_3 UBERON:0015917 biolink:AnatomicalEntity superficial lymph node A lymph node that is located close to the surface. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015917 CHEBI:58100 biolink:ChemicalSubstance N(6),N(6),N(6)-trimethyl-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58100 chebi_ph7_3 CHEBI:34157 biolink:ChemicalSubstance 14,15-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_34157 CHEBI:83120 biolink:ChemicalSubstance N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83120 chebi_ph7_3 UBERON:0015918 biolink:AnatomicalEntity deep lymph node A lymph node that is located deeper within the organism, further from the surface. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015918 CHEBI:34159 biolink:ChemicalSubstance 15-deoxy-Delta(12,14)-prostaglandin J2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_34159 CHEBI:58109 biolink:ChemicalSubstance (2-chloro-5-oxo-2,5-dihydro-2-furyl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58109 chebi_ph7_3 CHEBI:58106 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alaninate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58106 chebi_ph7_3 CHEBI:58105 biolink:ChemicalSubstance N(6)-[(indol-3-yl)acetyl]-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58105 chebi_ph7_3 CHEBI:58104 biolink:ChemicalSubstance nucleoside triphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58104 CHEBI:34151 biolink:ChemicalSubstance 12-oxo-ETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34151 CHEBI:58103 biolink:ChemicalSubstance 5,6,7,8-tetrahydromethanopterin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58103 chebi_ph7_3 CHEBI:34154 biolink:ChemicalSubstance 13(S)-HODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34154 CHEBI:58102 biolink:ChemicalSubstance 2-N,6-O-disulfonato-D-glucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58102 chebi_ph7_3 CHEBI:48775 biolink:ChemicalSubstance cadmium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48775 chebi_ph7_3 UBERON:0001348 biolink:AnatomicalEntity brown adipose tissue A thermogenic form of adipose tissue that is composed of brown adipocytes[MP,modified] go-plus.json textus adiposus fuscus|textus adiposus fuscus|BAT|adipocytus multigutturalis|brown fat|multilocular adipose tissue http://purl.obolibrary.org/obo/UBERON_0001348 CHEBI:83139 biolink:ChemicalSubstance long-chain fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83139 chebi_ph7_3 CHEBI:34127 biolink:ChemicalSubstance 11(R)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34127 CHEBI:34126 biolink:ChemicalSubstance 11(R)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34126 UBERON:0001356 biolink:AnatomicalEntity medial circumflex femoral artery The medial circumflex femoral artery (internal circumflex artery, medial femoral circumflex artery) is an artery in the upper thigh that helps supply blood to the neck of the femur. [WP,unvetted]. go-plus.json medial femoral circumflex artery|arteria circumflexa femoris medialis http://purl.obolibrary.org/obo/UBERON_0001356 UBERON:0001355 biolink:AnatomicalEntity deep femoral artery The profunda femoris artery (also known as the deep femoral artery, or the deep artery of the thigh) is a branch of the femoral artery that, as its name suggests, travels more deeply (posteriorly) than the rest of the femoral artery. [WP,unvetted]. go-plus.json arteria profunda femoris|profunda femoris artery http://purl.obolibrary.org/obo/UBERON_0001355 UBERON:0001352 biolink:AnatomicalEntity external acoustic meatus A tube running from the outer ear to the middle ear. The human ear canal extends from the pinna to the eardrum and is about 26 mm in length and 7 mm in diameter. go-plus.json auditory canal|external auditory meatus|external auditory tube|ear canal|external acoustic tube|external auditory canal|auditory meatus http://purl.obolibrary.org/obo/UBERON_0001352 UBERON:0001353 biolink:AnatomicalEntity anal region The anus and surrounding regions. Encompasses both internal and external regions, where present go-plus.json posterior|posterior end of organism http://purl.obolibrary.org/obo/UBERON_0001353 CHEBI:48765 biolink:ChemicalSubstance dimethylarsinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48765 UBERON:0001338 biolink:AnatomicalEntity urethral gland Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine go-plus.json urethra gland (male or female)|urethral mucuous gland|urethra gland|gland of urethra http://purl.obolibrary.org/obo/UBERON_0001338 GO:0047504 biolink:MolecularActivity (-)-menthol dehydrogenase activity Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH. MetaCyc:--MENTHOL-DEHYDROGENASE-RXN|RHEA:13917|KEGG_REACTION:R02177|UM-BBD_reactionID:r1182|EC:1.1.1.207 go-plus.json (-)-menthol:NADP+ oxidoreductase activity|monoterpenoid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047504 GO:0047503 biolink:MolecularActivity (-)-borneol dehydrogenase activity Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH. KEGG_REACTION:R02945|RHEA:22128|MetaCyc:--BORNEOL-DEHYDROGENASE-RXN|EC:1.1.1.227 go-plus.json (-)-borneol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047503 GO:0047502 biolink:MolecularActivity (+)-sabinol dehydrogenase activity Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH. KEGG_REACTION:R03745|RHEA:18329|EC:1.1.1.228|MetaCyc:+-SABINOL-DEHYDROGENASE-RXN go-plus.json (+)-cis-sabinol dehydrogenase activity|(+)-cis-sabinol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047502 GO:0047501 biolink:MolecularActivity (+)-neomenthol dehydrogenase activity Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH. KEGG_REACTION:R02548|RHEA:23812|EC:1.1.1.208|MetaCyc:+-NEOMENTHOL-DEHYDROGENASE-RXN go-plus.json monoterpenoid dehydrogenase activity|(+)-neomenthol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047501 GO:0047500 biolink:MolecularActivity (+)-borneol dehydrogenase activity Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH. EC:1.1.1.198|KEGG_REACTION:R02944|RHEA:17329|MetaCyc:+-BORNEOL-DEHYDROGENASE-RXN go-plus.json bicyclic monoterpenol dehydrogenase activity|(+)-borneol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047500 CHEBI:83148 biolink:ChemicalSubstance glycino(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_83148 chebi_ph7_3 CHEBI:83147 biolink:ChemicalSubstance 15alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83147 CHEBI:83146 biolink:ChemicalSubstance Daphnia tenebrosa metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_83146 CHEBI:83145 biolink:ChemicalSubstance carboxybiotinyl-L-lysine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83145 chebi_ph7_3 CHEBI:34133 biolink:ChemicalSubstance 11-oxotestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_34133 chebi_ph7_3 CHEBI:83144 biolink:ChemicalSubstance biotinyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83144 chebi_ph7_3 CHEBI:83143 biolink:ChemicalSubstance N(6)-[(R)-S(8)-ammoniomethyldihydrolipoyl]-L-lysine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83143 chebi_ph7_3 GO:0047509 biolink:MolecularActivity (R)-dehydropantoate dehydrogenase activity Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH. MetaCyc:R-DEHYDROPANTOATE-DEHYDROGENASE-RXN|EC:1.2.1.33|RHEA:19349|KEGG_REACTION:R03198 go-plus.json D-aldopantoate dehydrogenase activity|(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity|D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047509 CHEBI:83142 biolink:ChemicalSubstance N(6)-[(R)-S(8)-isobutyryldihydrolipoyl]-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83142 chebi_ph7_3 GO:0047508 biolink:MolecularActivity (R)-2-methylmalate dehydratase activity Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O. EC:4.2.1.35|MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN|KEGG_REACTION:R03896|RHEA:22332 go-plus.json (R)-2-methylmalate hydro-lyase activity|citraconate hydratase activity|citraconase activity|(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)|(-)-citramalate hydro-lyase activity|citramalate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047508 NCBITaxon:69014 biolink:OrganismalEntity Thermococcus kodakarensis KOD1 go-plus.json Thermococcus kodakaraensis KOD1|Pyrococcus sp. (strain KOD1)|Pyrococcus sp. KOD1|Thermococcus kodakarensis strain KOD1|Thermococcus kodakarensis str. KOD1 http://purl.obolibrary.org/obo/NCBITaxon_69014 GO:0047507 biolink:MolecularActivity (deoxy)nucleoside-phosphate kinase activity Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate. RHEA:11216|MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN|EC:2.7.4.13 go-plus.json deoxynucleoside-5'-monophosphate kinase activity|ATP:deoxynucleoside-phosphate phosphotransferase activity|deoxyribonucleoside monophosphokinase activity|deoxynucleoside monophosphate kinase activity http://purl.obolibrary.org/obo/GO_0047507 GO:0047506 biolink:MolecularActivity (deoxy)adenylate kinase activity Catalysis of the reaction: ATP + dAMP = ADP + dADP. MetaCyc:DEOXYADENYLATE-KINASE-RXN|EC:2.7.4.11|RHEA:23100 go-plus.json ATP:(d)AMP phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047506 GO:0047505 biolink:MolecularActivity (-)-menthol monooxygenase activity Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+). EC:1.14.13.46|MetaCyc:--MENTHOL-MONOOXYGENASE-RXN|RHEA:11648|KEGG_REACTION:R02178 go-plus.json (-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)|l-menthol monooxygenase activity http://purl.obolibrary.org/obo/GO_0047505 UBERON:0001344 biolink:AnatomicalEntity epithelium of vagina The epithelial layer of the vagina. go-plus.json epithelial tissue of vagina|epithelium, vaginal|vagina epithelial tissue|vagina epithelium|vaginal epithelium http://purl.obolibrary.org/obo/UBERON_0001344 UBERON:0001347 biolink:AnatomicalEntity white adipose tissue Connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels[MP,modified] go-plus.json textus adiposus albus|unilocular adipose tissue|textus adiposus albus|adipocytus unigutturalis|white fat http://purl.obolibrary.org/obo/UBERON_0001347 CHEBI:34130 biolink:ChemicalSubstance 11,12-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_34130 UBERON:0001343 biolink:AnatomicalEntity seminiferous tubule of testis The tubules in the testes where spermatogenesis occurs. go-plus.json seminiferous cord|testis - seminiferous tubule|tubuli seminiferi|seminiferous tubule|tubuli seminiferi http://purl.obolibrary.org/obo/UBERON_0001343 CHEBI:24786 biolink:ChemicalSubstance iminodiacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24786 CHEBI:24785 biolink:ChemicalSubstance iminodiacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24785 CHEBI:24783 biolink:ChemicalSubstance imine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24783 CHEBI:24789 biolink:ChemicalSubstance indanones go-plus.json http://purl.obolibrary.org/obo/CHEBI_24789 UBERON:0001328 biolink:AnatomicalEntity lobe of prostate A portion of a prostate that forms a lobe. go-plus.json prostate gland lobe|prostatic lobe|lobe of prostate gland http://purl.obolibrary.org/obo/UBERON_0001328 GO:0047515 biolink:MolecularActivity 1,3-beta-oligoglucan phosphorylase activity Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. EC:2.4.1.30|MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN|RHEA:16041 go-plus.json beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity|beta-1,3-oligoglucan phosphorylase activity|1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047515 GO:0047514 biolink:MolecularActivity 1,3-beta-D-glucan phosphorylase activity Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin. EC:2.4.1.97|MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN go-plus.json 1,3-beta-D-glucan:orthophosphate glucosyltransferase activity|1,3-beta-glucan phosphorylase activity|laminarin phosphoryltransferase activity|1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity|laminarin phosphorylase activity http://purl.obolibrary.org/obo/GO_0047514 GO:0047513 biolink:MolecularActivity 1,2-alpha-L-fucosidase activity Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside. MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN|RHEA:10816|EC:3.2.1.63 go-plus.json 2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity|almond emulsin fucosidase activity|alpha-(1->2)-L-fucosidase activity|almond emulsin fucosidase II activity http://purl.obolibrary.org/obo/GO_0047513 GO:0047512 biolink:MolecularActivity (S,S)-butanediol dehydrogenase activity Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH. RHEA:12184|KEGG_REACTION:R03707|MetaCyc:SS-BUTANEDIOL-DEHYDROGENASE-RXN|EC:1.1.1.76 go-plus.json L-BDH|L-butanediol dehydrogenase activity|L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)|(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047512 GO:0047511 biolink:MolecularActivity (S)-methylmalonyl-CoA hydrolase activity Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate. RHEA:17345|EC:3.1.2.17|KEGG_REACTION:R02764|MetaCyc:S-METHYLMALONYL-COA-HYDROLASE-RXN go-plus.json D-methylmalonyl-coenzyme A hydrolase activity http://purl.obolibrary.org/obo/GO_0047511 CHEBI:24782 biolink:ChemicalSubstance imide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24782 GO:0047510 biolink:MolecularActivity (S)-2-methylmalate dehydratase activity Catalysis of the reaction: S-citramalate = H(2)O + mesaconate. KEGG_REACTION:R03693|RHEA:13529|EC:4.2.1.34|MetaCyc:S-2-METHYLMALATE-DEHYDRATASE-RXN go-plus.json mesaconate mesaconase activity|(+)-citramalic hydro-lyase activity|(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)|(S)-2-methylmalate hydro-lyase activity|L-citramalate hydrolase activity|mesaconate hydratase activity|citramalate dehydratase activity|mesaconase activity|(+)-citramalate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047510 CHEBI:24781 biolink:ChemicalSubstance imidazolinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24781 CHEBI:24780 biolink:ChemicalSubstance imidazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_24780 GO:0047519 biolink:MolecularActivity quinate dehydrogenase (quinone) activity Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol. KEGG_REACTION:R01873|EC:1.1.5.8|RHEA:23672|MetaCyc:1.1.99.25-RXN go-plus.json quinate:quinone 3-oxidoreductase activity|NAD(P)-independent quinate dehydrogenase activity|quinate:pyrroloquinoline-quinone 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047519 GO:0047518 biolink:MolecularActivity 1-methyladenosine nucleosidase activity Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose. RHEA:12865|KEGG_REACTION:R03885|MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN|EC:3.2.2.13 go-plus.json 1-methyladenosine ribohydrolase activity|1-methyladenosine hydrolase activity http://purl.obolibrary.org/obo/GO_0047518 GO:0047517 biolink:MolecularActivity 1,4-beta-D-xylan synthase activity Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1). RHEA:15289|MetaCyc:RXN-9104|EC:2.4.2.24 go-plus.json uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity|xylan synthase activity|1,4-beta-xylan synthase activity|UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity|xylan synthetase activity http://purl.obolibrary.org/obo/GO_0047517 GO:0047516 biolink:MolecularActivity 1,3-propanediol dehydrogenase activity Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+. RHEA:23188|EC:1.1.1.202|MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN go-plus.json 1,3-propanediol oxidoreductase activity|1,3-propanediol:NAD+ oxidoreductase activity|1,3-PD:NAD+ oxidoreductase activity|propane-1,3-diol:NAD+ 1-oxidoreductase activity|3-hydroxypropionaldehyde reductase activity http://purl.obolibrary.org/obo/GO_0047516 UBERON:0001334 biolink:AnatomicalEntity female urethra A urethra that is part of a female reproductive system. go-plus.json urethra muliebris|urethra feminina http://purl.obolibrary.org/obo/UBERON_0001334 UBERON:0001333 biolink:AnatomicalEntity male urethra A urethra that is part of a male reproductive system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001333 UBERON:0001330 biolink:AnatomicalEntity pampiniform plexus The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]. go-plus.json venous plexus of fascia of prostate gland|plexus of veins of fascia of prostate|venous plexus of fascia of prostate|pampiniform venous plexus|plexus venosus pampiniformis http://purl.obolibrary.org/obo/UBERON_0001330 UBERON:0001331 biolink:AnatomicalEntity skin of penis A zone of skin that is part of a penis [Automatically generated definition]. go-plus.json zone of skin of penis|penis skin|penile skin|penis zone of skin http://purl.obolibrary.org/obo/UBERON_0001331 CHEBI:24797 biolink:ChemicalSubstance indole phytoalexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_24797 CHEBI:48742 biolink:ChemicalSubstance 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48742 CHEBI:48741 biolink:ChemicalSubstance beta-phellandrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48741 chebi_ph7_3 UBERON:0001319 biolink:AnatomicalEntity vaginal vein One the veins that drains the vaginal venous plexus, into the hypogastric veins. [WP,modified]. go-plus.json vein of vagina|vagina vein http://purl.obolibrary.org/obo/UBERON_0001319 CHEBI:24796 biolink:ChemicalSubstance indolylmethylglucosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24796 UBERON:0001317 biolink:AnatomicalEntity internal iliac vein A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted]. go-plus.json hypogastric vein|v. iliaca interna|v. hypogastrica http://purl.obolibrary.org/obo/UBERON_0001317 GO:0047526 biolink:MolecularActivity 2'-hydroxyisoflavone reductase activity Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+. MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN|EC:1.3.1.45|RHEA:22560 go-plus.json vestitone:NADP+ oxidoreductase activity|2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity|NADPH:2'-hydroxyisoflavone oxidoreductase activity|isoflavone reductase activity http://purl.obolibrary.org/obo/GO_0047526 GO:0047525 biolink:MolecularActivity 2'-hydroxydaidzein reductase activity Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+. MetaCyc:RXN-4502|EC:1.3.1.51|RHEA:17145 go-plus.json 2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity|HDR activity|2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity|NADPH:2'-hydroxydaidzein oxidoreductase activity|2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047525 GO:0047524 biolink:MolecularActivity 16-hydroxysteroid epimerase activity Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid. EC:5.1.99.2|RHEA:15829|MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN go-plus.json 16-hydroxysteroid 16-epimerase activity http://purl.obolibrary.org/obo/GO_0047524 GO:0047523 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047523 GO:0047522 biolink:MolecularActivity 15-oxoprostaglandin 13-oxidase activity Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+. EC:1.3.1.48|KEGG_REACTION:R04557|KEGG_REACTION:R04556|MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN go-plus.json (5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047522 CHEBI:24793 biolink:ChemicalSubstance indoledione go-plus.json http://purl.obolibrary.org/obo/CHEBI_24793 GO:0047521 biolink:MolecularActivity 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH. RHEA:21424|MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|KEGG_REACTION:R03495|EC:1.1.1.238 go-plus.json 12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity|12beta-hydroxysteroid dehydrogenase activity|12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|12-beta-hydroxysteroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047521 GO:0047520 biolink:MolecularActivity 11-cis-retinyl-palmitate hydrolase activity Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate. EC:3.1.1.63|KEGG_REACTION:R03049|MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN|Reactome:R-HSA-2465941|RHEA:19697 go-plus.json 11-cis-retinol palmitate esterase activity|11-cis-retinyl-palmitate acylhydrolase activity|RPH http://purl.obolibrary.org/obo/GO_0047520 CHEBI:83169 biolink:ChemicalSubstance N-acyl homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_83169 chebi_ph7_3 CHEBI:34116 biolink:ChemicalSubstance (9Z)-1-O-octadec-9-enyl glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34116 chebi_ph7_3 CHEBI:34115 biolink:ChemicalSubstance 1-O-hexadecyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34115 chebi_ph7_3 GO:0047529 biolink:MolecularActivity 2,3-dimethylmalate lyase activity Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate. EC:4.1.3.32|KEGG_REACTION:R01355|MetaCyc:23-DIMETHYLMALATE-LYASE-RXN|RHEA:10472 go-plus.json (2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)|(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity|2,3-dimethylmalate pyruvate-lyase activity http://purl.obolibrary.org/obo/GO_0047529 GO:0047528 biolink:MolecularActivity 2,3-dihydroxyindole 2,3-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+). EC:1.13.11.23|MetaCyc:23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN|KEGG_REACTION:R00983|RHEA:19445 go-plus.json 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity http://purl.obolibrary.org/obo/GO_0047528 CHEBI:34117 biolink:ChemicalSubstance batilol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34117 chebi_ph7_3 GO:0047527 biolink:MolecularActivity 2,3-dihydroxybenzoate-serine ligase activity Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine. EC:6.3.2.14|MetaCyc:23-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN|RHEA:30571 go-plus.json 2,3-dihydroxybenzoate:L-serine ligase activity|N-(2,3-dihydroxybenzoyl)-serine synthetase activity|2,3-dihydroxybenzoylserine synthetase activity http://purl.obolibrary.org/obo/GO_0047527 UBERON:0001325 biolink:AnatomicalEntity muscle of pelvis Muscle (organ) which is a part of the pelvis. Examples: levator ani, go-plus.json pelvis muscle organ|pelvic muscle|muscle organ of pelvis|pelvis muscle http://purl.obolibrary.org/obo/UBERON_0001325 CHEBI:143890 biolink:ChemicalSubstance 2-ammonioethyl (2R)-2,3-dihydroxypropyl phosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_143890 chebi_ph7_3 CHEBI:73702 biolink:ChemicalSubstance wax go-plus.json http://purl.obolibrary.org/obo/CHEBI_73702 CHEBI:73706 biolink:ChemicalSubstance bromosuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73706 chebi_ph7_3 CHEBI:73709 biolink:ChemicalSubstance (S)-2-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73709 chebi_ph7_3 CHEBI:73712 biolink:ChemicalSubstance bromosuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73712 CHEBI:58199 biolink:ChemicalSubstance L-homocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58199 chebi_ph7_3 CHEBI:58196 biolink:ChemicalSubstance (3R)-3-hydroxy-L-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58196 chebi_ph7_3 CHEBI:58195 biolink:ChemicalSubstance S-(5-deoxy-D-ribos-5-yl)-L-homocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58195 chebi_ph7_3 CHEBI:58194 biolink:ChemicalSubstance biochanin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58194 chebi_ph7_3 CHEBI:58193 biolink:ChemicalSubstance 3alpha(S)-strictosidinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58193 chebi_ph7_3 CHEBI:73722 biolink:ChemicalSubstance hexadecanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73722 CHEBI:73723 biolink:ChemicalSubstance N-oleoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73723 CHEBI:58192 biolink:ChemicalSubstance quercitrin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58192 chebi_ph7_3 CHEBI:58191 biolink:ChemicalSubstance 1-alkyl-2-acetyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58191 chebi_ph7_3 CHEBI:58190 biolink:ChemicalSubstance O-phosphonatoethanaminium(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58190 chebi_ph7_3 CHEBI:58189 biolink:ChemicalSubstance GDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58189 chebi_ph7_3 CHEBI:58188 biolink:ChemicalSubstance UDP-N-acetyl-D-galactosamine 4-sulfate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58188 chebi_ph7_3 CHEBI:58187 biolink:ChemicalSubstance alginate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58187 chebi_ph7_3 CHEBI:58186 biolink:ChemicalSubstance 1-phosphonato-alpha-D-galacturonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58186 chebi_ph7_3 CHEBI:58185 biolink:ChemicalSubstance 2-carboxylato-D-arabinitol 1-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58185 chebi_ph7_3 CHEBI:58184 biolink:ChemicalSubstance L-tyrosiniumyl-L-arginine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58184 chebi_ph7_3 CHEBI:58183 biolink:ChemicalSubstance 6-amino-2-oxohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58183 chebi_ph7_3 CHEBI:143878 biolink:ChemicalSubstance N-acetyl-D-phenylalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_143878 chebi_ph7_3 CHEBI:143877 biolink:ChemicalSubstance N-acetyl-L-tryptophanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_143877 chebi_ph7_3 CHEBI:58182 biolink:ChemicalSubstance (S)-6-hydroxynicotinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58182 chebi_ph7_3 CHEBI:73731 biolink:ChemicalSubstance (11Z,14Z)-icosadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73731 CHEBI:73730 biolink:ChemicalSubstance PPARbeta/delta agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_73730 CHEBI:58181 biolink:ChemicalSubstance trans-beta-D-glucosyl-2-hydroxycinnamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58181 chebi_ph7_3 CHEBI:58180 biolink:ChemicalSubstance L-arogenate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58180 chebi_ph7_3 CHEBI:58178 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 4-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58178 chebi_ph7_3 CHEBI:58177 biolink:ChemicalSubstance testolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58177 chebi_ph7_3 CHEBI:58176 biolink:ChemicalSubstance phenylthioacetohydroximate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58176 chebi_ph7_3 CHEBI:58175 biolink:ChemicalSubstance N-methyl-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58175 chebi_ph7_3 CHEBI:58174 biolink:ChemicalSubstance but-1-ene-1,2,4-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58174 chebi_ph7_3 CHEBI:58173 biolink:ChemicalSubstance L-gamma-glutamyl-L-cysteinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58173 chebi_ph7_3 CHEBI:58172 biolink:ChemicalSubstance dTDP-D-fucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58172 chebi_ph7_3 CHEBI:58171 biolink:ChemicalSubstance 7,8-dihydroxykynurenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58171 chebi_ph7_3 CHEBI:58179 biolink:ChemicalSubstance all-trans-hexaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58179 chebi_ph7_3 CHEBI:73743 biolink:ChemicalSubstance 2-(3-amino-3-carboxypropyl)-L-histidine zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73743 chebi_ph7_3 CHEBI:73745 biolink:ChemicalSubstance 2-[3-carboxylato-3-(dimethylammonio)propyl]-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73745 chebi_ph7_3 CHEBI:73747 biolink:ChemicalSubstance uridine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73747 chebi_ph7_3 CHEBI:58170 biolink:ChemicalSubstance psychosine sulfate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58170 chebi_ph7_3 CHEBI:58166 biolink:ChemicalSubstance CDP-4-dehydro-6-deoxy-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58166 chebi_ph7_3 CHEBI:58165 biolink:ChemicalSubstance 3',5'-cyclic AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58165 chebi_ph7_3 CHEBI:58164 biolink:ChemicalSubstance (S)-atropinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58164 chebi_ph7_3 CHEBI:58163 biolink:ChemicalSubstance homocystine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58163 chebi_ph7_3 CHEBI:58161 biolink:ChemicalSubstance L-cystathionine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58161 chebi_ph7_3 CHEBI:58169 biolink:ChemicalSubstance 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58169 chebi_ph7_3 CHEBI:58168 biolink:ChemicalSubstance 1-O-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58168 chebi_ph7_3 CHEBI:73754 biolink:ChemicalSubstance thiosugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_73754 CHEBI:73757 biolink:ChemicalSubstance Ala-Gly go-plus.json http://purl.obolibrary.org/obo/CHEBI_73757 CHEBI:58156 biolink:ChemicalSubstance N-adenylylanthranilate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58156 chebi_ph7_3 CHEBI:58155 biolink:ChemicalSubstance N-methyltyraminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58155 chebi_ph7_3 CHEBI:58154 biolink:ChemicalSubstance N-(2,3-dihydroxybenzoyl)-L-serinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58154 chebi_ph7_3 CHEBI:58153 biolink:ChemicalSubstance UDP-L-rhamnose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58153 chebi_ph7_3 CHEBI:58152 biolink:ChemicalSubstance cis-4-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58152 chebi_ph7_3 CHEBI:58151 biolink:ChemicalSubstance methanofuranate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58151 chebi_ph7_3 CHEBI:58150 biolink:ChemicalSubstance 3-D-glucuronosyl-N(2),6-disulfonato-beta-D-glucosamine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58150 chebi_ph7_3 CHEBI:58159 biolink:ChemicalSubstance uracil-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58159 chebi_ph7_3 CHEBI:58158 biolink:ChemicalSubstance aminomalonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58158 chebi_ph7_3 CHEBI:58157 biolink:ChemicalSubstance 2-O-caffeoylglucarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58157 chebi_ph7_3 CHEBI:73764 biolink:ChemicalSubstance 2-[3-carboxy-3-(dimethylamino)propyl]-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73764 CHEBI:73763 biolink:ChemicalSubstance 2-[3-carboxylato-3-(dimethylammonio)propyl]-L-histidine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73763 chebi_ph7_3 CHEBI:58145 biolink:ChemicalSubstance agmatinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58145 chebi_ph7_3 CHEBI:58144 biolink:ChemicalSubstance (R)-reticulinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58144 chebi_ph7_3 CHEBI:58143 biolink:ChemicalSubstance 5-dehydro-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58143 chebi_ph7_3 CHEBI:58142 biolink:ChemicalSubstance 4-carboxy-2-hydroxy-cis,cis-muconate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58142 chebi_ph7_3 CHEBI:58141 biolink:ChemicalSubstance P(1),P(4)-bis(5'-adenosyl) tetraphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58141 chebi_ph7_3 CHEBI:58140 biolink:ChemicalSubstance tetrahydropteroyltri-L-glutamate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58140 chebi_ph7_3 CHEBI:58149 biolink:ChemicalSubstance 3-hydroxyphenylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58149 chebi_ph7_3 CHEBI:58148 biolink:ChemicalSubstance L-homocitrulline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58148 chebi_ph7_3 CHEBI:58147 biolink:ChemicalSubstance 4-(2-aminophenyl)-2,4-dioxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58147 chebi_ph7_3 CHEBI:73762 biolink:ChemicalSubstance Ala-Thr go-plus.json http://purl.obolibrary.org/obo/CHEBI_73762 CHEBI:58146 biolink:ChemicalSubstance (R)-5-phosphonatomevalonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58146 chebi_ph7_3 GO:0072452 biolink:BiologicalProcess response to G2 transition size control checkpoint signaling A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling. go-plus.json G2/M transition size control checkpoint effector process|response to G2/M transition size control checkpoint signaling|response to mitotic cell cycle G2/M transition size control checkpoint signaling|response to signal involved in G2/M transition size control checkpoint http://purl.obolibrary.org/obo/GO_0072452 GO:0047496 biolink:BiologicalProcess vesicle transport along microtubule The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. go-plus.json microtubule-based vesicle localization http://purl.obolibrary.org/obo/GO_0047496 GO:0072451 biolink:BiologicalProcess obsolete detection of stimulus involved in G2 cell size control checkpoint OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a G2/M transition size control checkpoint. go-plus.json G2/M transition size control checkpoint sensor mechanism|G2/M transition size control checkpoint sensor process|detection of stimulus involved in G2/M transition size control checkpoint|detection of stimulus involved in mitotic cell cycle G2/M transition size control checkpoint|sensing involved in G2/M transition size control checkpoint http://purl.obolibrary.org/obo/GO_0072451 GO:0047495 biolink:MolecularActivity membrane-oligosaccharide glycerophosphotransferase activity Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another. EC:2.7.8.21|MetaCyc:2.7.8.21-RXN go-plus.json membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity|periplasmic phosphoglycerotransferase activity|phosphoglycerol cyclase activity http://purl.obolibrary.org/obo/GO_0047495 GO:0047494 biolink:MolecularActivity serine-phosphoethanolamine synthase activity Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+). RHEA:22656|EC:2.7.8.4|MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN|KEGG_REACTION:R02563 go-plus.json CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity|serine-phosphinico-ethanolamine synthase activity|serinephosphoethanolamine synthase activity|serine ethanolamine phosphodiester synthase activity|serine ethanolamine phosphate synthetase activity|serine ethanolaminephosphotransferase activity http://purl.obolibrary.org/obo/GO_0047494 GO:0072450 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072450 GO:0047493 biolink:MolecularActivity ceramide cholinephosphotransferase activity Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin. RHEA:16273|MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN|EC:2.7.8.3|KEGG_REACTION:R01891 go-plus.json phosphorylcholine-ceramide transferase activity|CDP-choline:N-acylsphingosine cholinephosphotransferase activity http://purl.obolibrary.org/obo/GO_0047493 GO:0047492 biolink:MolecularActivity xanthan lyase activity Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain. MetaCyc:4.2.2.12-RXN|EC:4.2.2.12 go-plus.json http://purl.obolibrary.org/obo/GO_0047492 GO:0047491 biolink:MolecularActivity poly(alpha-L-guluronate) lyase activity Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends. MetaCyc:4.2.2.11-RXN|EC:4.2.2.11 go-plus.json L-guluronan lyase activity|alginase II activity|poly(alpha-L-1,4-guluronide) exo-lyase activity|poly-alpha-L-guluronate lyase activity|polyguluronate-specific alginate lyase activity|guluronate lyase activity|L-guluronate lyase activity http://purl.obolibrary.org/obo/GO_0047491 GO:0047490 biolink:MolecularActivity pectin lyase activity Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends. MetaCyc:4.2.2.10-RXN|EC:4.2.2.10 go-plus.json endo-pectin lyase activity|PNL activity|pectin trans-eliminase activity|pectin methyltranseliminase activity|polymethylgalacturonic transeliminase activity|PL activity|pectolyase activity|(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity|PMGL activity http://purl.obolibrary.org/obo/GO_0047490 GO:0047499 biolink:MolecularActivity calcium-independent phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+. Reactome:R-HSA-8952251 go-plus.json calcium-independent cytosolic phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0047499 goslim_chembl GO:0047498 biolink:MolecularActivity calcium-dependent phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+. Reactome:R-HSA-111883 go-plus.json calcium-dependent cytosolic phospholipase A2 activity|calcium-dependent secreted phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0047498 GO:0047497 biolink:BiologicalProcess mitochondrion transport along microtubule The directed movement of a mitochondrion along a microtubule, mediated by motor proteins. go-plus.json mitochondrial migration along microtubule|mitochondrial transport along microtubule http://purl.obolibrary.org/obo/GO_0047497 GO:0072459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072459 GO:0072458 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072458 GO:0072457 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072457 GO:0072456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072456 GO:0072455 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072455 GO:0072454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072454 GO:0072453 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072453 GO:0072441 biolink:BiologicalProcess response to meiotic DNA replication checkpoint signaling A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling. go-plus.json response to signal involved in meiotic DNA replication checkpoint|meiotic DNA replication checkpoint effector process http://purl.obolibrary.org/obo/GO_0072441 GO:0072440 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072440 GO:0072449 biolink:BiologicalProcess response to G1 cell size control checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling. go-plus.json mitotic cell cycle G1/S transition size control checkpoint effector process|response to signal involved in mitotic cell cycle G1/S transition size control checkpoint http://purl.obolibrary.org/obo/GO_0072449 GO:0072448 biolink:BiologicalProcess obsolete detection of stimulus involved in G1 cell size control checkpoint OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition size control checkpoint. go-plus.json mitotic cell cycle G1/S transition size control checkpoint sensor mechanism|mitotic cell cycle G1/S transition size control checkpoint sensor process|detection of stimulus involved in mitotic cell cycle G1/S transition size control checkpoint|sensing involved in mitotic cell cycle G1/S transition size control checkpoint http://purl.obolibrary.org/obo/GO_0072448 GO:0072447 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072447 GO:0072446 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072446 GO:0072445 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072445 GO:0072444 biolink:BiologicalProcess response to mitotic DNA replication checkpoint signaling A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling. go-plus.json response to signal involved in S-M checkpoint|response to signal involved in mitotic DNA replication checkpoint|response to S-M checkpoint signaling|mitotic DNA replication checkpoint effector process|S-M checkpoint effector process http://purl.obolibrary.org/obo/GO_0072444 GO:0072443 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072443 GO:0072442 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic DNA replication checkpoint OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a mitotic DNA replication checkpoint. go-plus.json sensing involved in S-M checkpoint|mitotic DNA replication checkpoint sensor mechanism|sensing involved in mitotic DNA replication checkpoint|S-M checkpoint sensor mechanism|mitotic DNA replication checkpoint sensor process|S-M checkpoint sensor process|detection of stimulus involved in S-M checkpoint http://purl.obolibrary.org/obo/GO_0072442 GO:0072474 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072474 GO:0072473 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072473 GO:0072472 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072472 GO:0072471 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072471 GO:0072470 biolink:BiologicalProcess response to cell size control checkpoint signaling A process that occurs in response to signals generated as a result of cell size control checkpoint signaling. go-plus.json response to mitotic cell cycle cell size control checkpoint signaling|response to signal involved in cell size control checkpoint|cell size control checkpoint effector process http://purl.obolibrary.org/obo/GO_0072470 GO:0072479 biolink:BiologicalProcess response to mitotic cell cycle spindle assembly checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling. go-plus.json mitotic cell cycle spindle assembly checkpoint effector process|response to Dma1-dependent checkpoint signalling|response to signal involved in mitotic cell cycle spindle assembly checkpoint|response to Dma1-dependent checkpoint signaling http://purl.obolibrary.org/obo/GO_0072479 GO:0072478 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic spindle assembly checkpoint OBSOLETE. The series of events in which information about whether the spindle is correctly assembled, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle assembly checkpoint. go-plus.json mitotic cell cycle spindle assembly checkpoint sensor process|detection of stimulus involved in SAC-independent checkpoint|stimulus detection involved in DMA1-dependent checkpoint|perception of stimulus involved in DMA1-dependent checkpoint|stimulus sensing involved in SAC-independent checkpoint|perception of stimulus involved in SAC-independent checkpoint|stimulus sensing involved in DMA1-dependent checkpoint|detection of stimulus involved in mitotic cell cycle spindle assembly checkpoint|detection of stimulus involved in Dma1-dependent checkpoint|sensing involved in mitotic cell cycle spindle assembly checkpoint|mitotic cell cycle spindle assembly checkpoint sensor mechanism|stimulus detection involved in SAC-independent checkpoint http://purl.obolibrary.org/obo/GO_0072478 GO:0072477 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072477 GO:0072476 biolink:BiologicalProcess response to mitotic spindle checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling. go-plus.json response to mitotic cell cycle spindle checkpoint signaling|response to signal involved in mitotic cell cycle spindle checkpoint|mitotic cell cycle spindle checkpoint effector process http://purl.obolibrary.org/obo/GO_0072476 GO:0072475 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic spindle checkpoint OBSOLETE. The series of events in which information about whether the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle checkpoint. go-plus.json mitotic cell cycle spindle checkpoint sensor mechanism|mitotic cell cycle spindle checkpoint sensor process|detection of stimulus involved in mitotic cell cycle spindle checkpoint|sensing involved in mitotic cell cycle spindle checkpoint http://purl.obolibrary.org/obo/GO_0072475 GO:0072463 biolink:BiologicalProcess obsolete detection of stimulus involved in meiotic spindle assembly checkpoint OBSOLETE. The series of events in which information about whether spindle is correctly assembled and chromosomes are attached to the spindle is received and converted into a molecular signal, contributing to a meiotic spindle assembly checkpoint. go-plus.json meiotic spindle assembly checkpoint sensor mechanism|meiotic spindle assembly checkpoint sensor process|sensing involved in meiotic spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_0072463 GO:0072462 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072462 GO:0072461 biolink:BiologicalProcess response to meiotic recombination checkpoint signaling A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling. go-plus.json response to signal involved in meiotic recombination checkpoint|meiotic recombination checkpoint effector process http://purl.obolibrary.org/obo/GO_0072461 GO:0072460 biolink:BiologicalProcess obsolete detection of stimulus involved in meiotic recombination checkpoint OBSOLETE. The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint. go-plus.json meiotic recombination checkpoint sensor mechanism|sensing involved in meiotic recombination checkpoint|meiotic recombination checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072460 GO:0072469 biolink:BiologicalProcess obsolete detection of stimulus involved in cell size control checkpoint OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a cell size control checkpoint. go-plus.json cell size control checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle cell size control checkpoint|sensing involved in cell size control checkpoint|cell size control checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072469 GO:0072468 biolink:BiologicalProcess obsolete signal transduction involved in cell shape checkpoint OBSOLETE. A signal transduction process that contributes to a cell shape checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_0072468 GO:0072467 biolink:BiologicalProcess obsolete response to cell shape checkpoint signaling OBSOLETE. A process that occurs in response to signals generated as a result of cell shape checkpoint signaling. go-plus.json cell shape checkpoint effector process|response to signal involved in cell shape checkpoint http://purl.obolibrary.org/obo/GO_0072467 GO:0072466 biolink:BiologicalProcess obsolete detection of stimulus involved in cell shape checkpoint OBSOLETE. The series of events in which information about aspects of cell polarity control is received and converted into a molecular signal, contributing to a cell shape checkpoint. go-plus.json cell shape checkpoint sensor process|sensing involved in cell shape checkpoint|cell shape checkpoint sensor mechanism http://purl.obolibrary.org/obo/GO_0072466 GO:0072465 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072465 GO:0072464 biolink:BiologicalProcess response to meiotic spindle assembly checkpoint signaling A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling. go-plus.json response to signal involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint effector process http://purl.obolibrary.org/obo/GO_0072464 GO:0072496 biolink:MolecularActivity Pup transferase activity Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y --> Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages. go-plus.json Pup conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0072496 GO:0072495 biolink:CellularComponent host cell Cajal body A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction. go-plus.json coiled body of host|host cell coiled body http://purl.obolibrary.org/obo/GO_0072495 GO:0072494 biolink:CellularComponent host multivesicular body A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm. go-plus.json host cell multivesicular body http://purl.obolibrary.org/obo/GO_0072494 GO:0072493 biolink:CellularComponent host cell endosome lumen The volume enclosed by the membranes of the host cell endosome. go-plus.json host endosome lumen http://purl.obolibrary.org/obo/GO_0072493 GO:0072492 biolink:CellularComponent host cell mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0072492 GO:0072491 biolink:BiologicalProcess toluene-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives. go-plus.json toluene-containing compound degradation|toluene-containing compound breakdown|toluene-containing compound catabolism|toluene and derivative catabolic process http://purl.obolibrary.org/obo/GO_0072491 GO:0072490 biolink:BiologicalProcess toluene-containing compound metabolic process The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives. go-plus.json toluene-containing compound metabolism|toluene and derivative metabolic process http://purl.obolibrary.org/obo/GO_0072490 GO:0072499 biolink:BiologicalProcess photoreceptor cell axon guidance The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues. go-plus.json photoreceptor cell axon pathfinding http://purl.obolibrary.org/obo/GO_0072499 GO:0072498 biolink:BiologicalProcess embryonic skeletal joint development The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072498 GO:0072497 biolink:BiologicalProcess mesenchymal stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072497 GO:0072485 biolink:BiologicalProcess response to spindle assembly checkpoint signaling A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling. go-plus.json response to signal involved in spindle assembly checkpoint|spindle assembly checkpoint effector process http://purl.obolibrary.org/obo/GO_0072485 GO:0072484 biolink:BiologicalProcess obsolete detection of stimulus involved in spindle assembly checkpoint OBSOLETE. The series of events in which information about spindle assembly is received and converted into a molecular signal, contributing to a spindle assembly checkpoint. go-plus.json sensing involved in spindle assembly checkpoint|spindle assembly checkpoint sensor mechanism|spindle assembly checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072484 GO:0072483 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072483 GO:0072482 biolink:BiologicalProcess response to mitotic cell cycle spindle orientation checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling. go-plus.json response to signal involved in mitotic cell cycle spindle orientation checkpoint|mitotic cell cycle spindle orientation checkpoint effector process http://purl.obolibrary.org/obo/GO_0072482 GO:0072481 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic spindle orientation checkpoint OBSOLETE. The series of events in which information about whether the spindle is correctly oriented is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle orientation checkpoint. go-plus.json mitotic cell cycle spindle orientation checkpoint sensor mechanism|mitotic cell cycle spindle orientation checkpoint sensor process|detection of stimulus involved in mitotic cell cycle spindle orientation checkpoint|sensing involved in mitotic cell cycle spindle orientation checkpoint http://purl.obolibrary.org/obo/GO_0072481 GO:0072480 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072480 GO:0072489 biolink:BiologicalProcess methylammonium transmembrane transport The process in which methylammonium is transported across a membrane. go-plus.json methylammonium membrane transport http://purl.obolibrary.org/obo/GO_0072489 GO:0072488 biolink:BiologicalProcess ammonium transmembrane transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+. go-plus.json ammonium membrane transport http://purl.obolibrary.org/obo/GO_0072488 GO:0072487 biolink:CellularComponent MSL complex A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3. go-plus.json http://purl.obolibrary.org/obo/GO_0072487 GO:0072486 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072486 CHEBI:24768 biolink:ChemicalSubstance iduronates go-plus.json http://purl.obolibrary.org/obo/CHEBI_24768 CHEBI:24766 biolink:ChemicalSubstance iditol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24766 CHEBI:24765 biolink:ChemicalSubstance idaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24765 GO:0047416 biolink:MolecularActivity arylalkyl acylamidase activity Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine. EC:3.5.1.76|RHEA:10352|MetaCyc:3.5.1.76-RXN go-plus.json aralkyl acylamidase activity|N-acetylarylalkylamine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047416 OBO:GOCHE_39317 biolink:OntologyClass substance with growth regulator role go-plus.json http://purl.obolibrary.org/obo/GOCHE_39317 3_STAR GO:0047415 biolink:MolecularActivity D-benzoylarginine-4-nitroanilide amidase activity Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+). KEGG_REACTION:R04113|RHEA:14421|EC:3.5.1.72|MetaCyc:3.5.1.72-RXN go-plus.json D-BAPA-ase activity|N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity|benzoyl-D-arginine arylamidase activity http://purl.obolibrary.org/obo/GO_0047415 CHEBI:10119 biolink:ChemicalSubstance ziprasidone go-plus.json http://purl.obolibrary.org/obo/CHEBI_10119 GO:0047414 biolink:MolecularActivity 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+). EC:3.5.1.66|Wikipedia:2-(hydroxymethyl)-3-(acetamidomethylene)succinate_amidohydrolase_(deaminating,_decarboxylating)|RHEA:17677|KEGG_REACTION:R04397|MetaCyc:3.5.1.66-RXN go-plus.json alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity|2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)|compound B hydrolase activity http://purl.obolibrary.org/obo/GO_0047414 GO:0047413 biolink:MolecularActivity N(alpha)-benzyloxycarbonylleucine hydrolase activity Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2). EC:3.5.1.64|RHEA:18901|KEGG_REACTION:R02552|MetaCyc:3.5.1.64-RXN go-plus.json nalpha-benzyloxycarbonylleucine hydrolase activity|benzyloxycarbonylleucine hydrolase activity|alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV|nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity http://purl.obolibrary.org/obo/GO_0047413 GO:0047412 biolink:MolecularActivity N-(long-chain-acyl)ethanolamine deacylase activity Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid. RHEA:17505|EC:3.5.1.60|MetaCyc:3.5.1.60-RXN go-plus.json N-(long-chain-acyl)ethanolamine amidohydrolase activity|N-acylethanolamine amidohydrolase activity|acylethanolamine amidase activity http://purl.obolibrary.org/obo/GO_0047412 GO:0047411 biolink:MolecularActivity 2-(acetamidomethylene)succinate hydrolase activity Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate. EC:3.5.1.29|RHEA:10432|MetaCyc:3.5.1.29-RXN go-plus.json 2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)|alpha-(N-acetylaminomethylene)succinic acid hydrolase activity http://purl.obolibrary.org/obo/GO_0047411 GO:0047410 biolink:MolecularActivity N-formylmethionylaminoacyl-tRNA deformylase activity Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate. MetaCyc:3.5.1.27-RXN go-plus.json N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047410 CHEBI:83057 biolink:ChemicalSubstance Daphnia metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_83057 CHEBI:83056 biolink:ChemicalSubstance Daphnia magna metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_83056 UBERON:0001394 biolink:AnatomicalEntity axillary artery Artery that supplies the axilla go-plus.json axillary part of trunk of subclavian artery|arteria axillaris|axillary part of subclavian artery http://purl.obolibrary.org/obo/UBERON_0001394 CHEBI:83054 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_83054 GO:0047419 biolink:MolecularActivity N-acetylgalactosamine-6-phosphate deacetylase activity Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate. MetaCyc:3.5.1.80-RXN|EC:3.5.1.25|RHEA:18149 go-plus.json http://purl.obolibrary.org/obo/GO_0047419 CHEBI:10115 biolink:ChemicalSubstance zingiberene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10115 chebi_ph7_3 GO:0047418 biolink:MolecularActivity phthalyl amidase activity Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine. EC:3.5.1.79|RHEA:18297|MetaCyc:3.5.1.79-RXN go-plus.json phthalyl-amide amidohydrolase activity|o-phthalyl amidase activity http://purl.obolibrary.org/obo/GO_0047418 GO:0047417 biolink:MolecularActivity N-carbamoyl-D-amino acid hydrolase activity Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid. EC:3.5.1.77|RHEA:11000|MetaCyc:3.5.1.77-RXN go-plus.json N-carbamoyl-D-amino acid amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047417 CHEBI:24769 biolink:ChemicalSubstance iduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24769 CHEBI:24773 biolink:ChemicalSubstance 3-(imidazol-5-yl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24773 chebi_ph7_3 CHEBI:24779 biolink:ChemicalSubstance imidazolylacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_24779 CHEBI:48726 biolink:ChemicalSubstance nitroanisoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_48726 GO:0047427 biolink:MolecularActivity cyanoalanine nitrilase activity Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+). MetaCyc:3.5.5.4-RXN|KEGG_REACTION:R00486|EC:3.5.5.4|RHEA:11188 go-plus.json 3-cyano-L-alanine aminohydrolase activity|beta-cyanoalanine nitrilase activity http://purl.obolibrary.org/obo/GO_0047427 GO:0047426 biolink:MolecularActivity ricinine nitrilase activity Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone. RHEA:22704|MetaCyc:3.5.5.2-RXN|EC:3.5.5.2 go-plus.json ricinine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047426 GO:0047425 biolink:MolecularActivity 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+). KEGG_REACTION:R02280|MetaCyc:3.5.4.22-RXN|EC:3.5.4.22|RHEA:10560 go-plus.json HPC deaminase activity|1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing) http://purl.obolibrary.org/obo/GO_0047425 GO:0047424 biolink:MolecularActivity methylenediurea deaminase activity Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea. MetaCyc:3.5.3.21-RXN|RHEA:15929|EC:3.5.3.21 go-plus.json methylenediurease activity|methylenediurea aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047424 CHEBI:10106 biolink:ChemicalSubstance zearalenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_10106 chebi_ph7_3 GO:0047423 biolink:MolecularActivity N-methylhydantoinase (ATP-hydrolyzing) activity Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate. MetaCyc:3.5.2.14-RXN|EC:3.5.2.14|RHEA:11720|Wikipedia:N-methylhydantoinase_(ATP-hydrolysing)|KEGG_REACTION:R03187 go-plus.json N-methylhydantoinase (ATP-hydrolysing)|N-methylhydantoin amidohydrolase activity|methylhydantoin amidase activity|N-methylhydantoinase activity|N-methylhydantoin hydrolase activity|N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing) http://purl.obolibrary.org/obo/GO_0047423 GO:0047422 biolink:MolecularActivity N-acyl-D-aspartate deacylase activity Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate. KEGG_REACTION:R02182|RHEA:18285|MetaCyc:3.5.1.83-RXN|EC:3.5.1.83 go-plus.json N-acyl-D-aspartate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047422 GO:0047421 biolink:MolecularActivity N-acyl-D-glutamate deacylase activity Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate. MetaCyc:3.5.1.82-RXN|RHEA:12833|EC:3.5.1.82|KEGG_REACTION:R01581 go-plus.json N-acyl-D-glutamate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047421 GO:0047420 biolink:MolecularActivity N-acyl-D-amino-acid deacylase activity Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid. MetaCyc:3.5.1.81-RXN|RHEA:18309|EC:3.5.1.81 go-plus.json D-aminoacylase activity|N-acyl-D-amino acid amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047420 UBERON:0001383 biolink:AnatomicalEntity muscle of leg A muscle that is part of the region of the hindlimb between the pelvis and ankle. go-plus.json skeletal muscle of leg|muscle of upper/lower leg|muscle of thigh or crus|leg skeletal muscle|leg muscle|muscle organ of leg|muscle of upper or lower hindlimb segment|leg skeletal muscle tissue|muscle of hindlimb zeugopod or stylopod|leg muscle organ http://purl.obolibrary.org/obo/UBERON_0001383 CHEBI:83064 biolink:ChemicalSubstance 3'-end ribonucleotide 2',3'-cyclic phosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83064 chebi_ph7_3 GO:0047429 biolink:MolecularActivity nucleoside-triphosphate diphosphatase activity Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide. MetaCyc:3.6.1.19-RXN|EC:3.6.1.9 go-plus.json nucleoside-triphosphate diphosphohydrolase activity|nucleoside-triphosphate pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0047429 CHEBI:83062 biolink:ChemicalSubstance 3'-end ribonucleotide 3'-phosphate(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83062 chebi_ph7_3 GO:0047428 biolink:MolecularActivity arylacetonitrilase activity Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3. RHEA:20657|MetaCyc:3.5.5.5-RXN|EC:3.5.5.5 go-plus.json arylacetonitrile aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047428 GO:0047430 biolink:MolecularActivity oligosaccharide-diphosphodolichol diphosphatase activity Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate. EC:3.6.1.44|RHEA:15205|MetaCyc:3.6.1.44-RXN go-plus.json oligosaccharide-diphosphodolichol pyrophosphatase activity|oligosaccharide-diphosphodolichol phosphodolichohydrolase activity http://purl.obolibrary.org/obo/GO_0047430 CHEBI:24745 biolink:ChemicalSubstance hydroxypyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24745 CHEBI:24744 biolink:ChemicalSubstance 2-hydroxypropyl-CoM go-plus.json http://purl.obolibrary.org/obo/CHEBI_24744 GO:0047438 biolink:MolecularActivity 2-dehydro-3-deoxy-L-pentonate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate. EC:4.1.2.18|RHEA:18545|MetaCyc:4.1.2.18-RXN go-plus.json 2-keto-3-deoxy-D-xylonate aldolase activity|2-keto-3-deoxy-L-pentonate aldolase activity|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)|3-deoxy-D-pentulosonic acid aldolase|2-keto-3-deoxy-L-arabonate aldolase activity http://purl.obolibrary.org/obo/GO_0047438 GO:0047437 biolink:MolecularActivity 4-oxalocrotonate decarboxylase activity Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate. UM-BBD_reactionID:r1435|EC:4.1.1.77|RHEA:24260|MetaCyc:4.1.1.77-RXN go-plus.json 4-oxalocrotonate carboxy-lyase activity|4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming) http://purl.obolibrary.org/obo/GO_0047437 GO:0047436 biolink:MolecularActivity arylmalonate decarboxylase activity Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2). RHEA:20513|EC:4.1.1.76|KEGG_REACTION:R05173|MetaCyc:4.1.1.76-RXN go-plus.json AMDase activity|2-aryl-2-methylmalonate carboxy-lyase activity|2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)|AMDASE http://purl.obolibrary.org/obo/GO_0047436 GO:0047435 biolink:MolecularActivity 5-guanidino-2-oxopentanoate decarboxylase activity Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2). EC:4.1.1.75|KEGG_REACTION:R03178|RHEA:11340|MetaCyc:4.1.1.75-RXN go-plus.json 2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)|2-oxo-5-guanidinopentanoate carboxy-lyase activity|2-oxo-5-guanidinopentanoate decarboxylase activity|alpha-ketoarginine decarboxylase activity|2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity http://purl.obolibrary.org/obo/GO_0047435 GO:0047434 biolink:MolecularActivity indolepyruvate decarboxylase activity Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde. EC:4.1.1.74|RHEA:18017|MetaCyc:4.1.1.74-RXN go-plus.json 3-(indol-3-yl)pyruvate carboxy-lyase activity|indole-3-pyruvate decarboxylase activity|indol-3-yl-pyruvate carboxy-lyase activity|3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming] http://purl.obolibrary.org/obo/GO_0047434 GO:0047433 biolink:MolecularActivity branched-chain-2-oxoacid decarboxylase activity Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2). RHEA:21108|EC:4.1.1.72|KEGG_REACTION:R03894|MetaCyc:4.1.1.72-RXN go-plus.json branched-chain keto acid decarboxylase activity|(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)|(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity|branched-chain oxo acid decarboxylase activity|branched-chain alpha-keto acid decarboxylase activity|BCKA http://purl.obolibrary.org/obo/GO_0047433 GO:0047432 biolink:MolecularActivity 2,2-dialkylglycine decarboxylase (pyruvate) activity Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone. EC:4.1.1.64|KEGG_REACTION:R03854|RHEA:16073|MetaCyc:4.1.1.64-RXN go-plus.json alpha-dialkyl amino acid transaminase activity|2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity|L-alanine-alpha-ketobutyrate aminotransferase activity|2,2-dialkylglycine carboxy-lyase (amino-transferring)|dialkyl amino acid (pyruvate) decarboxylase activity|2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)|dialkylamino-acid decarboxylase (pyruvate) http://purl.obolibrary.org/obo/GO_0047432 GO:0047431 biolink:MolecularActivity 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2). RHEA:13669|EC:4.1.1.51|KEGG_REACTION:R03461|MetaCyc:4.1.1.51-RXN go-plus.json 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)|3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0047431 GO:0047439 biolink:MolecularActivity 3-deoxy-D-manno-octulosonate aldolase activity Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate. EC:4.1.2.23|KEGG_REACTION:R01576|RHEA:23340|MetaCyc:4.1.2.23-RXN go-plus.json 2-keto-3-deoxyoctonic aldolase activity|3-deoxy-D-manno-octulosonic aldolase activity|3-deoxyoctulosonic aldolase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)|2-keto-3-deoxyoctonate aldolase activity|KDOaldolase activity http://purl.obolibrary.org/obo/GO_0047439 OIO:hasOBOFormatVersion biolink:OntologyClass has_obo_format_version go-plus.json http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion CHEBI:83072 biolink:ChemicalSubstance EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_83072 CHEBI:83071 biolink:ChemicalSubstance tRNA 3'-terminal nucleotidyl-cytidyl-cytidyl-adenosine(4-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83071 chebi_ph7_3 CHEBI:48717 biolink:ChemicalSubstance 9,9',15-tri-cis-zeta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48717 chebi_ph7_3 CHEBI:48716 biolink:ChemicalSubstance 9,9'-di-cis-zeta-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48716 chebi_ph7_3 CHEBI:24747 biolink:ChemicalSubstance hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24747 GO:0047441 biolink:MolecularActivity 5-dehydro-2-deoxyphosphogluconate aldolase activity Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate. EC:4.1.2.29|KEGG_REACTION:R05378|MetaCyc:4.1.2.29-RXN|RHEA:13177 go-plus.json phospho-5-dehydro-2-deoxygluconate aldolase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)|phospho-5-keto-2-deoxygluconate aldolase activity http://purl.obolibrary.org/obo/GO_0047441 CHEBI:24753 biolink:ChemicalSubstance hygromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_24753 GO:0047440 biolink:MolecularActivity 2-dehydro-3-deoxy-D-pentonate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate. RHEA:20609|EC:4.1.2.28|KEGG_REACTION:R01782|MetaCyc:4.1.2.28-RXN go-plus.json 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity|3-deoxy-D-pentulosonic acid aldolase|2-keto-3-deoxy-D-pentonate aldolase activity http://purl.obolibrary.org/obo/GO_0047440 CHEBI:24751 biolink:ChemicalSubstance hydroxytoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_24751 CHEBI:24757 biolink:ChemicalSubstance hypochlorous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24757 chebi_ph7_3 UBERON:0001359 biolink:AnatomicalEntity cerebrospinal fluid A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord. go-plus.json cerebral spinal fluid|liquor cerebrospinalis|CSF|spinal fluid http://purl.obolibrary.org/obo/UBERON_0001359 CHEBI:48701 biolink:ChemicalSubstance 7alpha,24-dihydroxycholest-4-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48701 chebi_ph7_3 GO:0047449 biolink:MolecularActivity 2-dehydro-3-deoxy-L-arabinonate dehydratase activity Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O. MetaCyc:4.2.1.43-RXN|EC:4.2.1.43|KEGG_REACTION:R02278|RHEA:17201 go-plus.json 2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity|2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)|2-keto-3-deoxy-L-arabinonate dehydratase activity http://purl.obolibrary.org/obo/GO_0047449 GO:0047448 biolink:MolecularActivity 5-dehydro-4-deoxyglucarate dehydratase activity Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O. MetaCyc:4.2.1.41-RXN|RHEA:24608|EC:4.2.1.41|KEGG_REACTION:R02279 go-plus.json 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)|5-keto-4-deoxy-glucarate dehydratase activity|5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)|deoxyketoglucarate dehydratase activity|D-4-deoxy-5-ketoglucarate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047448 GO:0047447 biolink:MolecularActivity erythro-3-hydroxyaspartate ammonia-lyase activity Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid. MetaCyc:4.3.1.20-RXN|EC:4.3.1.20|RHEA:19757 go-plus.json erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity|3-hydroxyaspartate dehydratase activity|erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity|erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)|erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)|erythro-3-hydroxyaspartate dehydratase activity|erythro-beta-hydroxyaspartate dehydratase activity http://purl.obolibrary.org/obo/GO_0047447 GO:0047446 biolink:MolecularActivity (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone. MetaCyc:4.1.3.35-RXN|RHEA:23868|EC:4.1.3.35|KEGG_REACTION:R02232 go-plus.json (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)|(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity http://purl.obolibrary.org/obo/GO_0047446 GO:0047445 biolink:MolecularActivity 3-hydroxy-3-isohexenylglutaryl-CoA lyase activity Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate. RHEA:23084|MetaCyc:4.1.3.26-RXN|KEGG_REACTION:R08090|EC:4.1.3.26|UM-BBD_reactionID:r1168 go-plus.json 3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity|beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity|hydroxyisohexenylglutaryl-CoA:acetatelyase activity|3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity http://purl.obolibrary.org/obo/GO_0047445 GO:0047444 biolink:MolecularActivity N-acylneuraminate-9-phosphate synthase activity Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate. Reactome:R-HSA-4084976|MetaCyc:4.1.3.20-RXN|EC:2.5.1.57|RHEA:13421 go-plus.json N-acetylneuraminate 9-phosphate synthetase activity|N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity|N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity|phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity|N-acetylneuraminate 9-phosphate lyase activity|sialic acid 9-phosphate synthetase activity|N-acetylneuraminic acid phosphate synthase activity http://purl.obolibrary.org/obo/GO_0047444 GO:0047443 biolink:MolecularActivity 4-hydroxy-4-methyl-2-oxoglutarate aldolase activity Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate. EC:4.1.3.17|RHEA:22748|MetaCyc:4.1.3.17-RXN go-plus.json 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity|4-hydroxy-4-methyl-2-ketoglutarate aldolase activity|pyruvate aldolase activity|4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)|gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity http://purl.obolibrary.org/obo/GO_0047443 GO:0047442 biolink:MolecularActivity 17-alpha-hydroxyprogesterone aldolase activity Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione. MetaCyc:4.1.2.30-RXN|EC:4.1.2.30|RHEA:14753 go-plus.json C-17/C-20 lyase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)|17alpha-hydroxyprogesterone aldolase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase activity|17-alpha-hydroxyprogesterone acetaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0047442 CHEBI:83088 biolink:ChemicalSubstance (R)-lipoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83088 chebi_ph7_3 CHEBI:48706 biolink:ChemicalSubstance antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48706 CHEBI:48705 biolink:ChemicalSubstance agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48705 UBERON:0001366 biolink:AnatomicalEntity parietal peritoneum The outer layer of peritoneum that is attached to the abdominal and pelvic walls. go-plus.json parietal serous membrane of peritoneum|peritoneal cavity lining http://purl.obolibrary.org/obo/UBERON_0001366 GO:0047452 biolink:MolecularActivity protoaphin-aglucone dehydratase (cyclizing) activity Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin. RHEA:23876|KEGG_REACTION:R03742|EC:4.2.1.73|MetaCyc:4.2.1.73-RXN go-plus.json protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)|protoaphin dehydratase activity|protoaphin dehydratase (cyclizing)|protoaphin-aglucone hydro-lyase (cyclizing) http://purl.obolibrary.org/obo/GO_0047452 GO:0047451 biolink:MolecularActivity 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein]. KEGG_REACTION:R04537|MetaCyc:4.2.1.59-RXN|EC:4.2.1.59|RHEA:41844 go-plus.json 3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity|D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity|D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity|(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity|beta-hydroxyoctanoyl thioester dehydratase activity|beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity|3-hydroxyoctanoyl-ACP dehydratase activity|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity|beta-hydroxyoctanoyl-ACP-dehydrase activity|3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity http://purl.obolibrary.org/obo/GO_0047451 GO:0047450 biolink:MolecularActivity crotonoyl-[acyl-carrier-protein] hydratase activity Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein]. MetaCyc:4.2.1.58-RXN|EC:4.2.1.58|KEGG_REACTION:R04428 go-plus.json 3-hydroxybutyryl acyl carrier protein dehydratase activity|(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)|beta-hydroxybutyryl acyl carrier protein dehydrase activity|enoyl acyl carrier protein hydrase activity|crotonyl acyl carrier protein hydratase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity|crotonoyl-ACP hydratase activity|beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity|crotonoyl-acyl-carrier-protein hydratase activity|crotonoyl-[acyl-carrier protein] hydratase activity http://purl.obolibrary.org/obo/GO_0047450 GO:0047459 biolink:MolecularActivity 3-aminobutyryl-CoA ammonia-lyase activity Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+). EC:4.3.1.14|RHEA:10056|KEGG_REACTION:R03030|MetaCyc:4.3.1.14-RXN go-plus.json L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)|L-3-aminobutyryl-CoA ammonia-lyase activity|L-3-aminobutyryl-CoA deaminase activity http://purl.obolibrary.org/obo/GO_0047459 GO:0047458 biolink:MolecularActivity beta-pyrazolylalanine synthase activity Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+). RHEA:13117|EC:2.5.1.51|KEGG_REACTION:R03134|MetaCyc:2.5.1.51-RXN go-plus.json pyrazolylalaninase activity|3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|O3-acetyl-L-serine acetate-lyase (adding pyrazole)|beta-(1-pyrazolyl)alanine synthase activity|BPA-synthase activity|O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity|beta-pyrazolealanine synthase activity|pyrazolealanine synthase activity|O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|beta-pyrazolylalanine synthase (acetylserine) activity http://purl.obolibrary.org/obo/GO_0047458 GO:0047457 biolink:MolecularActivity exo-(1,4)-alpha-D-glucan lyase activity Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose. EC:4.2.2.13|MetaCyc:4.2.2.13-RXN go-plus.json exo-alpha-1,4-glucan lyase activity|(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)|alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity|exo-(1->4)-alpha-D-glucan lyase activity|alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity|alpha-1,4-glucan lyase activity|alpha-1,4-glucan exo-lyase activity http://purl.obolibrary.org/obo/GO_0047457 GO:0047456 biolink:MolecularActivity 2-methylisocitrate dehydratase activity Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O. EC:4.2.1.99|KEGG_REACTION:R04425|RHEA:17941|MetaCyc:4.2.1.99-RXN go-plus.json (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming] http://purl.obolibrary.org/obo/GO_0047456 GO:0047455 biolink:MolecularActivity 16-alpha-hydroxyprogesterone dehydratase activity Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone. EC:4.2.1.98|RHEA:12584|MetaCyc:4.2.1.98-RXN go-plus.json 16-alpha-hydroxyprogesterone dehydroxylase activity|16-alpha-dehydroxylase activity|16alpha-hydroxyprogesterone dehydroxylase activity|16alpha-dehydroxylase activity|16alpha-hydroxyprogesterone dehydratase activity|16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)|16alpha-hydroxyprogesterone hydro-lyase activity|hydroxyprogesterone dehydroxylase activity|16-dehydroprogesterone hydratase activity http://purl.obolibrary.org/obo/GO_0047455 GO:0047454 biolink:MolecularActivity phaseollidin hydratase activity Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin. EC:4.2.1.97|RHEA:19769|MetaCyc:4.2.1.97-RXN|KEGG_REACTION:R04728 go-plus.json phaseollidin-hydrate hydro-lyase activity|phaseollidin-hydrate hydro-lyase (phaseollidin-forming) http://purl.obolibrary.org/obo/GO_0047454 GO:0047453 biolink:MolecularActivity ATP-dependent NAD(P)H-hydrate dehydratase activity Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate. EC:4.2.1.93|RHEA:19017|Reactome:R-HSA-6806967|MetaCyc:4.2.1.93-RXN|KEGG_REACTION:R00129 go-plus.json (6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)|ATP-dependent H4NAD(P)OH dehydratase activity|reduced nicotinamide adenine dinucleotide hydrate dehydratase activity|ATP-dependent H(4)NAD(P)OH dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming) http://purl.obolibrary.org/obo/GO_0047453 CHEBI:83099 biolink:ChemicalSubstance N(6)-[(R)-lipoyl]-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83099 chebi_ph7_3 GO:0072419 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072419 CHEBI:83096 biolink:ChemicalSubstance (R)-S(6)-acetyldihydrolipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_83096 chebi_ph7_3 GO:0072418 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072418 GO:0072417 biolink:BiologicalProcess response to spindle checkpoint signaling A process that occurs in response to signals generated as a result of spindle checkpoint signaling. go-plus.json response to signal involved in spindle checkpoint|spindle checkpoint effector process http://purl.obolibrary.org/obo/GO_0072417 CHEBI:83094 biolink:ChemicalSubstance (R)-lipoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_83094 chebi_ph7_3 GO:0072416 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072416 CHEBI:83093 biolink:ChemicalSubstance (R)-dihydrolipoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83093 chebi_ph7_3 GO:0072415 biolink:BiologicalProcess obsolete detection of stimulus involved in spindle checkpoint OBSOLETE. The series of events in which information about the assembly, orientation or integrity of the spindle is received and converted into a molecular signal, contributing to a spindle checkpoint. go-plus.json spindle checkpoint sensor mechanism|sensing involved in spindle checkpoint|spindle checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072415 CHEBI:24727 biolink:ChemicalSubstance hydroxynaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_24727 GO:0072414 biolink:BiologicalProcess response to mitotic cell cycle checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling. go-plus.json response to signal involved in mitotic cell cycle checkpoint|response to mitotic G2/M transition checkpoint signal|response to signal involved in mitotic cell cycle G1/S checkpoint|mitotic G2/M transition checkpoint effector process|response to signal involved in mitotic G2/M transition checkpoint|mitotic cell cycle G1/S checkpoint effector process|mitotic cell cycle checkpoint effector process|response to mitotic cell cycle G1/S checkpoint signaling http://purl.obolibrary.org/obo/GO_0072414 CHEBI:83091 biolink:ChemicalSubstance (R)-lipoyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83091 chebi_ph7_3 GO:0072413 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072413 GO:0072412 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic cell cycle checkpoint OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a mitotic cell cycle checkpoint. go-plus.json sensing involved in mitotic cell cycle G1/S checkpoint|sensing involved in mitotic cell cycle checkpoint|mitotic cell cycle G1/S checkpoint sensor process|mitotic cell cycle checkpoint sensor mechanism|mitotic cell cycle checkpoint sensor process|mitotic cell cycle G1/S checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle G1/S checkpoint http://purl.obolibrary.org/obo/GO_0072412 GO:0072411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072411 GO:0072410 biolink:BiologicalProcess response to meiotic cell cycle checkpoint signaling A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint. go-plus.json response to signal involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint effector process http://purl.obolibrary.org/obo/GO_0072410 CHEBI:24729 biolink:ChemicalSubstance 6-hydroxynicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24729 CHEBI:24731 biolink:ChemicalSubstance hydroxyphenylacetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_24731 SO:0000110 biolink:SequenceFeature sequence_feature Any extent of continuous biological sequence. go-plus.json located_sequence_feature|located sequence feature|INSDC_note:other|INSDC_feature:misc_feature|sequence feature|INSDC_note:sequence_feature http://purl.obolibrary.org/obo/SO_0000110 SOFA GO:0047463 biolink:MolecularActivity 2-aminohexano-6-lactam racemase activity Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam. EC:5.1.1.15|KEGG_REACTION:R04736|RHEA:14813|MetaCyc:5.1.1.15-RXN go-plus.json 2-amino-hexano-6-lactam racemase activity|alpha-amino-epsilon-caprolactam racemase activity http://purl.obolibrary.org/obo/GO_0047463 GO:0047462 biolink:MolecularActivity phenylalanine racemase (ATP-hydrolyzing) activity Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+). EC:5.1.1.11|KEGG_REACTION:R00686|RHEA:20201|MetaCyc:5.1.1.11-RXN go-plus.json phenylalanine racemase (adenosine triphosphate-hydrolysing)|phenylalanine racemase (ATP-hydrolysing)|gramicidin S synthetase I|phenylalanine racemase activity http://purl.obolibrary.org/obo/GO_0047462 CHEBI:24730 biolink:ChemicalSubstance hydroxynitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_24730 GO:0047461 biolink:MolecularActivity (+)-delta-cadinene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene. MetaCyc:4.6.1.11-RXN|EC:4.2.3.13|RHEA:19525 go-plus.json 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)|D-cadinene synthase activity http://purl.obolibrary.org/obo/GO_0047461 GO:0047460 biolink:MolecularActivity L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+). KEGG_REACTION:R02605|MetaCyc:4.5.1.4-RXN|RHEA:11620|EC:4.5.1.4 go-plus.json L-2-amino-4-chloro-4-pentenoate dehalogenase activity|L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)|L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating) http://purl.obolibrary.org/obo/GO_0047460 CHEBI:24734 biolink:ChemicalSubstance hydroxyphenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24734 GO:0047469 biolink:MolecularActivity 4-carboxymethyl-4-methylbutenolide mutase activity Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide. KEGG_REACTION:R04510|MetaCyc:5.4.99.14-RXN|RHEA:19237|EC:5.4.99.14 go-plus.json 4-methyl-2-enelactone methyl-isomerase activity|4-methyl-3-enelactone methyl isomerase activity|4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity|4-methylmuconolactone methylisomerase activity|4-methyl-2-enelactone isomerase activity http://purl.obolibrary.org/obo/GO_0047469 GO:0047468 biolink:MolecularActivity phosphoglucomutase (glucose-cofactor) activity Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor. MetaCyc:5.4.2.5-RXN|EC:5.4.2.5 go-plus.json glucose-1-phosphate phosphotransferase activity|alpha-D-glucose 1,6-phosphomutase (glucose-cofactor) http://purl.obolibrary.org/obo/GO_0047468 GO:0047467 biolink:MolecularActivity 4-hydroxyphenylacetaldehyde-oxime isomerase activity Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime. go-plus.json http://purl.obolibrary.org/obo/GO_0047467 GO:0047466 biolink:MolecularActivity 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide. MetaCyc:5.2.1.10-RXN|RHEA:10924|UM-BBD_reactionID:r0278|EC:5.2.1.10|KEGG_REACTION:R04576 go-plus.json 2-chlorocarboxymethylenebutenolide isomerase activity|2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity|chlorodienelactone isomerase activity http://purl.obolibrary.org/obo/GO_0047466 GO:0047465 biolink:MolecularActivity N-acylglucosamine-6-phosphate 2-epimerase activity Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. MetaCyc:5.1.3.9-RXN|RHEA:23932|EC:5.1.3.9 go-plus.json N-acyl-D-glucosamine-6-phosphate 2-epimerase activity|acylglucosamine-6-phosphate 2-epimerase activity|acylmannosamine phosphate 2-epimerase activity|acylglucosamine phosphate 2-epimerase activity|N-acetylglucosmamine 6-phosphate 2-epimerase activity|N-acetylmannosamine-6-phosphate 2-epimerase activity http://purl.obolibrary.org/obo/GO_0047465 GO:0047464 biolink:MolecularActivity heparosan-N-sulfate-glucuronate 5-epimerase activity Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate. EC:5.1.3.17|RHEA:20197|MetaCyc:5.1.3.17-RXN go-plus.json poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity|heparosan epimerase activity|D-glucuronyl C-5 epimerase activity|polyglucuronate epimerase activity|heparosan-N-sulphate-glucuronate 5-epimerase activity|heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity|C-5 uronosyl epimerase activity http://purl.obolibrary.org/obo/GO_0047464 GO:0072409 biolink:BiologicalProcess obsolete detection of stimulus involved in meiotic cell cycle checkpoint OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a meiotic cell cycle checkpoint. go-plus.json meiotic cell cycle checkpoint sensor process|sensing involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint sensor mechanism http://purl.obolibrary.org/obo/GO_0072409 GO:0072408 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072408 GO:0072407 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072407 GO:0072406 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072406 GO:0072405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072405 GO:0072404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072404 GO:0072403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072403 GO:0072402 biolink:BiologicalProcess response to DNA integrity checkpoint signaling A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling. go-plus.json DNA integrity checkpoint effector process|response to signal involved in DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_0072402 GO:0072401 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072401 GO:0072400 biolink:BiologicalProcess obsolete detection of stimulus involved in mitotic DNA integrity checkpoint OBSOLETE. The series of events in which information about DNA integrity is received and converted into a molecular signal, contributing to a mitotic DNA integrity checkpoint. go-plus.json mitotic G2/M transition decatenation checkpoint sensor process|DNA integrity checkpoint sensor mechanism|DNA integrity checkpoint sensor process|mitotic G2/M transition decatenation checkpoint sensor mechanism|detection of stimulus involved in mitotic G2/M transition decatenation checkpoint|sensing involved in mitotic G2/M transition decatenation checkpoint|sensing involved in DNA integrity checkpoint http://purl.obolibrary.org/obo/GO_0072400 GO:0047474 biolink:MolecularActivity long-chain fatty acid luciferin component ligase activity Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. RHEA:20101|MetaCyc:6.2.1.19-RXN|EC:6.2.1.19 go-plus.json long-chain-fatty-acid:protein ligase (AMP-forming)|acyl-protein synthetase activity|long-chain-fatty-acid-luciferin-component ligase activity|long-chain-fatty-acid luciferin component ligase activity http://purl.obolibrary.org/obo/GO_0047474 GO:0072430 biolink:BiologicalProcess obsolete detection of DNA damage stimulus involved in mitotic G1 DNA damage checkpoint OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition DNA damage checkpoint. go-plus.json sensing involved in mitotic cell cycle G1/S transition DNA damage checkpoint|detection of DNA damage stimulus involved in mitotic cell cycle G1/S transition DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint sensor mechanism|mitotic cell cycle G1/S transition DNA damage checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072430 GO:0047473 biolink:MolecularActivity D-alanine [D-alanyl carrier protein] ligase activity Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate. MetaCyc:6.2.1.M5-RXN|EC:6.2.1.- go-plus.json D-alanine:poly(phosphoribitol) ligase (AMP-forming)|D-alanine-activating enzyme activity|D-alanine-poly(phosphoribitol) ligase activity|D-alanine-D-alanyl carrier protein ligase activity http://purl.obolibrary.org/obo/GO_0047473 GO:0047472 biolink:MolecularActivity 3-carboxy-cis,cis-muconate cycloisomerase activity Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+). MetaCyc:5.5.1.2-RXN|UM-BBD_reactionID:r0582|EC:5.5.1.2|KEGG_REACTION:R03307|RHEA:23656 go-plus.json 3-carboxymuconate lactonizing enzyme activity|beta-carboxymuconate lactonizing enzyme activity|3-carboxymuconate cycloisomerase type II activity|CMLE activity|3-carboxymuconolactone hydrolase activity http://purl.obolibrary.org/obo/GO_0047472 GO:0047471 biolink:MolecularActivity maltose alpha-D-glucosyltransferase activity Catalysis of the reaction: maltose = trehalose. MetaCyc:5.4.99.16-RXN|RHEA:15145|EC:5.4.99.16 go-plus.json maltose glucosylmutase activity|trehalose synthase activity|maltose alpha-D-glucosylmutase activity http://purl.obolibrary.org/obo/GO_0047471 GO:0047470 biolink:MolecularActivity (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside. RHEA:13621|MetaCyc:5.4.99.15-RXN|EC:5.4.99.15 go-plus.json maltodextrin alpha-D-glucosyltransferase activity|malto-oligosyltrehalose synthase activity|(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase http://purl.obolibrary.org/obo/GO_0047470 GO:0047479 biolink:MolecularActivity trypanothione synthase activity Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate. EC:6.3.1.9|RHEA:21532|MetaCyc:6.3.1.9-RXN go-plus.json glutathionylspermidine:glutathione ligase (ADP-forming)|TSR synthetase activity http://purl.obolibrary.org/obo/GO_0047479 GO:0047478 biolink:MolecularActivity aspartate-ammonia ligase (ADP-forming) activity Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate. MetaCyc:6.3.1.4-RXN|EC:6.3.1.4|KEGG_REACTION:R00482|RHEA:14197 go-plus.json asparagine synthetase (ADP-forming) activity|asparagine synthetase (adenosine diphosphate-forming)|L-aspartate:ammonia ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0047478 GO:0047477 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047477 GO:0047476 biolink:MolecularActivity 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP. MetaCyc:6.2.1.28-RXN|EC:6.2.1.28|RHEA:21776 go-plus.json 3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|DHCA-CoA ligase activity|3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity|3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0047476 GO:0047475 biolink:MolecularActivity phenylacetate-CoA ligase activity Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA. EC:6.2.1.30|MetaCyc:PHENYLACETATE--COA-LIGASE-RXN|RHEA:20956|KEGG_REACTION:R02539 go-plus.json phenylacetyl-CoA ligase activity|phenylacetyl-CoA ligase (AMP-forming)|PA-CoA ligase activity|phenacyl coenzyme A synthetase activity|phenylacetate:CoA ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0047475 GO:0072439 biolink:BiologicalProcess obsolete detection of stimulus involved in meiotic DNA replication checkpoint OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a meiotic DNA replication checkpoint. go-plus.json meiotic DNA replication checkpoint sensor mechanism|meiotic DNA replication checkpoint sensor process|sensing involved in meiotic DNA replication checkpoint http://purl.obolibrary.org/obo/GO_0072439 GO:0072438 biolink:BiologicalProcess response to DNA replication checkpoint signaling A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling. go-plus.json DNA replication checkpoint effector process|response to signal involved in DNA replication checkpoint http://purl.obolibrary.org/obo/GO_0072438 CHEBI:24705 biolink:ChemicalSubstance hydroxykynurenamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24705 GO:0072437 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072437 GO:0072436 biolink:BiologicalProcess obsolete detection of stimulus involved in DNA replication checkpoint OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint. go-plus.json sensing involved in DNA replication checkpoint|DNA replication checkpoint sensor mechanism|DNA replication checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072436 GO:0072435 biolink:BiologicalProcess response to mitotic G2 DNA damage checkpoint signaling A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling. go-plus.json response to signal involved in mitotic G2/M transition decatenation checkpoint|mitotic G2/M transition DNA damage checkpoint effector process|response to mitotic G2/M transition DNA damage checkpoint signaling|mitotic G2/M transition decatenation checkpoint effector process|response to mitotic G2/M transition decatenation checkpoint signaling|response to signal involved in mitotic G2/M transition DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0072435 GO:0072434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072434 GO:0072433 biolink:BiologicalProcess obsolete detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic G2/M transition DNA damage checkpoint. go-plus.json mitotic G2/M transition DNA damage checkpoint sensor mechanism|sensing involved in mitotic G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint sensor mechanism|mitotic G2/M transition DNA damage checkpoint sensor process|detection of DNA damage stimulus involved in G2/M transition DNA damage checkpoint|detection of DNA damage stimulus involved in mitotic G2/M transition DNA damage checkpoint|detection of DNA damage stimulus involved in G2 DNA damage checkpoint|sensing involved in G2/M transition DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0072433 CHEBI:24709 biolink:ChemicalSubstance hydroxylamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24709 GO:0072432 biolink:BiologicalProcess response to G1 DNA damage checkpoint signaling A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling. go-plus.json response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint effector process|response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling http://purl.obolibrary.org/obo/GO_0072432 GO:0072431 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072431 PR:000009182 biolink:Protein insulin-like growth factor I A protein that is a translation product of the human IGF1 gene or a 1:1 ortholog thereof. go-plus.json IGF1|Igf-1|somatomedin|MGF|somatomedin-C|IGF-I|mechano growth factor http://purl.obolibrary.org/obo/PR_000009182 GO:0047485 biolink:MolecularActivity protein N-terminus binding Binding to a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. go-plus.json amino-terminus binding|NH2-terminal binding|N-terminal end binding|NH2-terminus binding|N-terminal binding|amino-terminal binding http://purl.obolibrary.org/obo/GO_0047485 GO:0047484 biolink:BiologicalProcess regulation of response to osmotic stress Any process that modulates the rate or extent of the response to osmotic stress. go-plus.json http://purl.obolibrary.org/obo/GO_0047484 GO:0047483 biolink:MolecularActivity imidazoleacetate-phosphoribosyldiphosphate ligase activity Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate. MetaCyc:6.3.4.8-RXN|EC:6.3.4.8|KEGG_REACTION:R04068|RHEA:16485 go-plus.json 5-phosphoribosylimidazoleacetate synthetase activity|imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming) http://purl.obolibrary.org/obo/GO_0047483 GO:0047482 biolink:MolecularActivity UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine. MetaCyc:6.3.2.7-RXN|RHEA:17969|KEGG_REACTION:R02786|EC:6.3.2.7 go-plus.json UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity|MurE synthetase activity|L-lysine-adding enzyme activity|UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity http://purl.obolibrary.org/obo/GO_0047482 GO:0047481 biolink:MolecularActivity D-alanine-alanyl-poly(glycerolphosphate) ligase activity Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP. EC:6.3.2.16|MetaCyc:6.3.2.16-RXN go-plus.json D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity|D-alanylalanylpoly(phosphoglycerol) synthetase activity|D-alanine:membrane-acceptor ligase activity|D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)|D-alanine-membrane acceptor-ligase activity|D-alanyl-poly(phosphoglycerol) synthetase activity http://purl.obolibrary.org/obo/GO_0047481 GO:0047480 biolink:MolecularActivity UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP. EC:6.3.2.10|RHEA:16085|MetaCyc:6.3.2.10-RXN go-plus.json UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity|UDP-MurNAc-pentapeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)|UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity|UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity|UDPacetylmuramoylpentapeptide synthetase activity|MurF synthetase activity|uridine diphosphoacetylmuramoylpentapeptide synthetase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity http://purl.obolibrary.org/obo/GO_0047480 CHEBI:24712 biolink:ChemicalSubstance hydroxymethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24712 chebi_ph7_3 CHEBI:24711 biolink:ChemicalSubstance hydroxymalonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24711 GO:0047489 biolink:MolecularActivity pectate disaccharide-lyase activity Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin. MetaCyc:4.2.2.9-RXN|RHEA:57104|EC:4.2.2.9 go-plus.json Exo-PATE activity|exopolygalacturonate lyase activity|exopectate lyase activity|(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity|exopectic acid transeliminase activity|exo-PATE|pectate exo-lyase activity|PATE activity|Exo-PGL activity|exo-PGL|exopolygalacturonic acid-trans-eliminase activity http://purl.obolibrary.org/obo/GO_0047489 GO:0047488 biolink:MolecularActivity heparin lyase activity Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends. MetaCyc:4.2.2.7-RXN|EC:4.2.2.7 go-plus.json heparan sulfate lyase activity|heparinase activity|heparin eliminase activity http://purl.obolibrary.org/obo/GO_0047488 GO:0047487 biolink:MolecularActivity oligogalacturonide lyase activity Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate. RHEA:20269|EC:4.2.2.6|MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN go-plus.json OGTE|oligogalacturonate lyase activity|unsaturated oligogalacturonate transeliminase activity http://purl.obolibrary.org/obo/GO_0047487 GO:0047486 biolink:MolecularActivity chondroitin ABC lyase activity Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0047486 GO:0072429 biolink:BiologicalProcess response to intra-S DNA damage checkpoint signaling A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling. go-plus.json intra-S DNA damage checkpoint effector process|response to signal involved in intra-S DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0072429 GO:0072428 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072428 GO:0072427 biolink:BiologicalProcess obsolete detection of DNA damage stimulus involved in intra-S DNA damage checkpoint OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint. go-plus.json intra-S DNA damage checkpoint sensor process|intra-S DNA damage checkpoint sensor mechanism|sensing involved in intra-S DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0072427 GO:0072426 biolink:BiologicalProcess response to G2 DNA damage checkpoint signaling A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling. go-plus.json response to signal involved in G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint effector process http://purl.obolibrary.org/obo/GO_0072426 GO:0072425 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072425 GO:0072424 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072424 GO:0072423 biolink:BiologicalProcess response to DNA damage checkpoint signaling A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling. go-plus.json response to signal involved in DNA damage checkpoint|DNA damage checkpoint effector process http://purl.obolibrary.org/obo/GO_0072423 GO:0072422 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072422 GO:0072421 biolink:BiologicalProcess obsolete detection of DNA damage stimulus involved in DNA damage checkpoint OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a DNA damage checkpoint. go-plus.json DNA damage checkpoint sensor mechanism|DNA damage checkpoint sensor process|sensing involved in DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0072421 GO:0072420 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072420 UBERON:0001425 biolink:AnatomicalEntity pectoral lymphatic vessel go-plus.json PL http://purl.obolibrary.org/obo/UBERON_0001425 CHEBI:48691 biolink:ChemicalSubstance 3-(cis-5,6-dihydroxycyclohexa-1,3-dienyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48691 CHEBI:58013 biolink:ChemicalSubstance aspulvinone H(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58013 chebi_ph7_3 CHEBI:58012 biolink:ChemicalSubstance strictosidine aglycone(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58012 chebi_ph7_3 CHEBI:58011 biolink:ChemicalSubstance (1R,2R,3R)-prephytoene diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58011 chebi_ph7_3 CHEBI:34047 biolink:ChemicalSubstance 1,2-dihydrostilbene go-plus.json http://purl.obolibrary.org/obo/CHEBI_34047 chebi_ph7_3 CHEBI:58010 biolink:ChemicalSubstance (S)-3'-hydroxy-N-methylcoclaurinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58010 chebi_ph7_3 UBERON:0001435 biolink:AnatomicalEntity carpal bone A bone that is part of the carpal skeleton. Examples: scaphoid, lunate, capitate[cjm]. go-plus.json carpal skeleton bone|carpal|bone of carpus|carpus bone http://purl.obolibrary.org/obo/UBERON_0001435 UBERON:0001434 biolink:AnatomicalEntity skeletal system Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. go-plus.json skeleton system|set of all bones and joints|Skelettsystem http://purl.obolibrary.org/obo/UBERON_0001434 CHEBI:58018 biolink:ChemicalSubstance N(5)-formyl-5,6,7,8-tetrahydromethanopterin(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58018 chebi_ph7_3 CHEBI:58017 biolink:ChemicalSubstance 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58017 chebi_ph7_3 CHEBI:58016 biolink:ChemicalSubstance 1-guanidiniumyl-1-deoxy-scyllo-inositol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58016 chebi_ph7_3 CHEBI:58015 biolink:ChemicalSubstance 7,8-dihydro-7,8-dihydroxykynurenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58015 chebi_ph7_3 CHEBI:58014 biolink:ChemicalSubstance 1-alkyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58014 chebi_ph7_3 UBERON:0001419 biolink:AnatomicalEntity skin of limb A zone of skin that is part of a limb [Automatically generated definition]. go-plus.json limb zone of skin|zone of skin of limb|limb skin http://purl.obolibrary.org/obo/UBERON_0001419 UBERON:0001418 biolink:AnatomicalEntity skin of thorax A zone of skin that is part of a thorax [Automatically generated definition]. go-plus.json thorax zone of skin|upper body skin|thorax skin|thoracic skin|zone of skin of thorax http://purl.obolibrary.org/obo/UBERON_0001418 UBERON:0001415 biolink:AnatomicalEntity skin of pelvis A zone of skin that is part of a pelvis [Automatically generated definition]. go-plus.json zone of skin of pelvis|pelvic skin|pelvis skin|pelvis zone of skin http://purl.obolibrary.org/obo/UBERON_0001415 UBERON:0001417 biolink:AnatomicalEntity skin of neck A zone of skin that is part of a neck [Automatically generated definition]. go-plus.json neck skin|zone of skin of neck|neck zone of skin|zone of skin of neck (volume)|neck (volume) zone of skin http://purl.obolibrary.org/obo/UBERON_0001417 UBERON:0001416 biolink:AnatomicalEntity skin of abdomen A zone of skin that is part of an abdomen [Automatically generated definition]. go-plus.json abdomen skin|zone of skin of abdomen|skin of abdomen proper|abdominal skin|abdomen zone of skin http://purl.obolibrary.org/obo/UBERON_0001416 CHEBI:48681 biolink:ChemicalSubstance 2,3-dihydroxycinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48681 CHEBI:48683 biolink:ChemicalSubstance piperazinecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48683 CHEBI:58002 biolink:ChemicalSubstance L-erythrulose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58002 chebi_ph7_3 CHEBI:58001 biolink:ChemicalSubstance primary aliphatic ammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58001 chebi_ph7_3 CHEBI:58000 biolink:ChemicalSubstance D-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58000 chebi_ph7_3 UBERON:0001422 biolink:AnatomicalEntity facial lymphatic vessel A lymphatic vessel that is part of a face [Automatically generated definition]. go-plus.json buccal lymphatic vessel|lymph vessel of face|face lymph vessel|FL|lymphatic vessel of face|face lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001422 UBERON:0001421 biolink:AnatomicalEntity pectoral girdle region An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. go-plus.json shoulder girdle|cingulum membri superioris|cingulum membri superioris|upper limb girdle|pectoral region|girdle - pectoral|pectoral girdle http://purl.obolibrary.org/obo/UBERON_0001421 CHEBI:58009 biolink:ChemicalSubstance L-gamma-glutamyl-L-cysteinyl-beta-alaninate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58009 chebi_ph7_3 CHEBI:58008 biolink:ChemicalSubstance 2-carboxylato-D-arabinitol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58008 chebi_ph7_3 CHEBI:58007 biolink:ChemicalSubstance streptomycin(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58007 chebi_ph7_3 CHEBI:58006 biolink:ChemicalSubstance Cypridina luciferin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58006 chebi_ph7_3 CHEBI:58005 biolink:ChemicalSubstance N-amidino-L-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58005 chebi_ph7_3 CHEBI:58004 biolink:ChemicalSubstance 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58004 chebi_ph7_3 CHEBI:58003 biolink:ChemicalSubstance 3',5'-cyclic CMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58003 chebi_ph7_3 PR:000024939 biolink:Protein interferon beta go-plus.json IFNB http://purl.obolibrary.org/obo/PR_000024939 CHEBI:48676 biolink:ChemicalSubstance fibrin modulating drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48676 CHEBI:73675 biolink:ChemicalSubstance 6''-O-carbamoylkanamycin A(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73675 chebi_ph7_3 CHEBI:48675 biolink:ChemicalSubstance antifibrinolytic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48675 CHEBI:73678 biolink:ChemicalSubstance tobramycin(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73678 chebi_ph7_3 CHEBI:73677 biolink:ChemicalSubstance (S)-alpha-hydroxyglutaric acid-gamma-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_73677 CHEBI:48679 biolink:ChemicalSubstance sorbopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48679 CHEBI:73679 biolink:ChemicalSubstance nebramycin 5'(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73679 chebi_ph7_3 CHEBI:73672 biolink:ChemicalSubstance cyclic ADP-ribose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73672 chebi_ph7_3 CHEBI:73674 biolink:ChemicalSubstance carbamoyl adenylate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73674 chebi_ph7_3 CHEBI:73673 biolink:ChemicalSubstance (S)-alpha-hydroxyglutarate-gamma-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_73673 chebi_ph7_3 CHEBI:73687 biolink:ChemicalSubstance L-threonylcarbamoyladenylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73687 CHEBI:48664 biolink:ChemicalSubstance xylo-hexos-2-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48664 CHEBI:73686 biolink:ChemicalSubstance nebramycin 5' go-plus.json http://purl.obolibrary.org/obo/CHEBI_73686 CHEBI:48666 biolink:ChemicalSubstance D-xylo-hexos-2-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48666 chebi_ph7_3 CHEBI:73688 biolink:ChemicalSubstance Ac-Asp-Glu go-plus.json http://purl.obolibrary.org/obo/CHEBI_73688 GO:0047603 biolink:MolecularActivity acetoacetyl-CoA hydrolase activity Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+). EC:3.1.2.11|KEGG_REACTION:R01358|RHEA:15673|MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN go-plus.json acetoacetyl coenzyme A hydrolase activity|acetoacetyl coenzyme A deacylase activity|acetoacetyl CoA deacylase activity http://purl.obolibrary.org/obo/GO_0047603 GO:0047602 biolink:MolecularActivity acetoacetate decarboxylase activity Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2). RHEA:19729|KEGG_REACTION:R01366|MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN|EC:4.1.1.4 go-plus.json acetoacetate carboxy-lyase (acetone-forming)|acetoacetic acid decarboxylase activity|acetoacetate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0047602 GO:0047601 biolink:MolecularActivity acetate kinase (diphosphate) activity Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate. EC:2.7.2.12|KEGG_REACTION:R00320|RHEA:24276|MetaCyc:ACETATE-KINASE-PYROPHOSPHATE-RXN go-plus.json pyrophosphate-acetate phosphotransferase activity|diphosphate:acetate phosphotransferase activity|acetate kinase (pyrophosphate) activity http://purl.obolibrary.org/obo/GO_0047601 GO:0047600 biolink:MolecularActivity abequosyltransferase activity Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid. EC:2.4.1.60|RHEA:34183|MetaCyc:ABEQUOSYLTRANSFERASE-RXN go-plus.json trihexose diphospholipid abequosyltransferase activity|CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity http://purl.obolibrary.org/obo/GO_0047600 GO:0047609 biolink:MolecularActivity acetylputrescine deacetylase activity Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine. RHEA:23412|KEGG_REACTION:R01156|EC:3.5.1.62|MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN go-plus.json N-acetylputrescine acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0047609 GO:0047608 biolink:MolecularActivity acetylindoxyl oxidase activity Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown. RHEA:16941|EC:1.7.3.2|MetaCyc:ACETYLINDOXYL-OXIDASE-RXN go-plus.json N-acetylindoxyl:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047608 GO:0047607 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047607 GO:0047606 biolink:MolecularActivity hydroxynitrilase activity Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone. EC:4.1.2.47|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN go-plus.json 2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)|hydroxynitrile lyase activity|acetone-cyanhydrin lyase activity|acetone-cyanohydrin acetone-lyase activity|alpha-hydroxynitrile lyase activity|(S)-acetone-cyanohydrin lyase activity|acetone-cyanohydrin acetone-lyase (cyanide-forming)|oxynitrilase activity|2-hydroxyisobutyronitrile acetone-lyase activity|acetone-cyanohydrin lyase activity http://purl.obolibrary.org/obo/GO_0047606 GO:0047605 biolink:MolecularActivity acetolactate decarboxylase activity Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2. RHEA:21580|EC:4.1.1.5|MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN go-plus.json alpha-acetolactate decarboxylase activity|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming] http://purl.obolibrary.org/obo/GO_0047605 GO:0047604 biolink:MolecularActivity acetoin racemase activity Catalysis of the reaction: (S)-acetoin = (R)-acetoin. MetaCyc:ACETOIN-RACEMASE-RXN|EC:5.1.2.4|RHEA:12092|KEGG_REACTION:R02949 go-plus.json acetylmethylcarbinol racemase activity http://purl.obolibrary.org/obo/GO_0047604 CHEBI:73680 biolink:ChemicalSubstance carbamoyl adenylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73680 CHEBI:73683 biolink:ChemicalSubstance 6''-O-carbamoylkanamycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_73683 CHEBI:73682 biolink:ChemicalSubstance L-threonylcarbamoyladenylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73682 chebi_ph7_3 CHEBI:73684 biolink:ChemicalSubstance carbamoylkanamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_73684 CHEBI:24685 biolink:ChemicalSubstance hydroxybutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_24685 CHEBI:24684 biolink:ChemicalSubstance hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24684 DDANAT:0010085 biolink:OntologyClass subdivision Anatomical structure which is a primary subdivision of whole Dictyostelium organism. The mereological sum of these is the whole organism. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0010085 UBERON:0001469 biolink:AnatomicalEntity sternoclavicular joint The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted]. go-plus.json articulatio sternoclavicularis|sternoclavicular|sterno clavicular joint|sternoclavicular articulation http://purl.obolibrary.org/obo/UBERON_0001469 CHEBI:48657 biolink:ChemicalSubstance L-xylo-hexos-2-ulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48657 chebi_ph7_3 CHEBI:24689 biolink:ChemicalSubstance hydroxycinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24689 CHEBI:24688 biolink:ChemicalSubstance monohydroxycinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24688 DDANAT:0010082 biolink:OntologyClass whole organism Anatomical structure that is an individual member of the Dictyostelium discoideum species and consists of more than one cell. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0010082 GO:0047614 biolink:MolecularActivity aconitate delta-isomerase activity Catalysis of the reaction: trans-aconitate = cis-aconitate. EC:5.3.3.7|MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN|KEGG_REACTION:R02244|RHEA:17265 go-plus.json aconitate D-isomerase activity|aconitate delta2-delta3-isomerase activity|aconitate isomerase activity http://purl.obolibrary.org/obo/GO_0047614 GO:0047613 biolink:MolecularActivity aconitate decarboxylase activity Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate. MetaCyc:ACONITATE-DECARBOXYLASE-RXN|KEGG_REACTION:R02243|EC:4.1.1.6|RHEA:15253 go-plus.json cis-aconitate carboxy-lyase (itaconate-forming)|cis-aconitate carboxy-lyase activity|CAD activity|cis-aconitic decarboxylase activity http://purl.obolibrary.org/obo/GO_0047613 GO:0047612 biolink:MolecularActivity acid-CoA ligase (GDP-forming) activity Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate. RHEA:10968|EC:6.2.1.10|KEGG_REACTION:R00394|MetaCyc:ACID--COA-LIGASE-GDP-FORMING-RXN go-plus.json acid:CoA ligase (GDP-forming)|acyl-CoA synthetase (GDP-forming) activity|acyl coenzyme A synthetase (guanosine diphosphate forming) http://purl.obolibrary.org/obo/GO_0047612 GO:0047611 biolink:MolecularActivity acetylspermidine deacetylase activity Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine. RHEA:23928|MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN|EC:3.5.1.48|KEGG_REACTION:R07300 go-plus.json N(1)-acetylspermidine amidohydrolase activity|8-N-acetylspermidine amidohydrolase activity|N(8)-acetylspermidine deacetylase activity|N8-acetylspermidine deacetylase activity|N-acetylspermidine deacetylase activity|N(8)-monoacetylspermidine deacetylase activity|N8-monoacetylspermidine deacetylase activity|N1-acetylspermidine amidohydrolase activity|N8-acetylspermidine amidohydrolase activity|N(8)-acetylspermidine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047611 GO:0047610 biolink:MolecularActivity acetylsalicylate deacetylase activity Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate. MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN|EC:3.1.1.55|KEGG_REACTION:R02942|RHEA:11752 go-plus.json aspirin esterase activity|acetylsalicylate O-acetylhydrolase activity|aspirin hydrolase activity|acetylsalicylic acid esterase activity http://purl.obolibrary.org/obo/GO_0047610 CHEBI:48652 biolink:ChemicalSubstance 1,3-thiazolemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48652 CHEBI:24681 biolink:ChemicalSubstance hydroxybiphenyls go-plus.json http://purl.obolibrary.org/obo/CHEBI_24681 CHEBI:34002 biolink:ChemicalSubstance (3S)-3-Hydroxyadipyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_34002 GO:0047619 biolink:MolecularActivity acylcarnitine hydrolase activity Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine. RHEA:17101|MetaCyc:ACYLCARNITINE-HYDROLASE-RXN|EC:3.1.1.28 go-plus.json carnitine ester hydrolase activity|long-chain acyl-L-carnitine hydrolase activity|palmitoyl-L-carnitine hydrolase activity|O-acylcarnitine acylhydrolase activity|high activity acylcarnitine hydrolase activity|palmitoylcarnitine hydrolase activity|HACH|palmitoyl carnitine hydrolase activity http://purl.obolibrary.org/obo/GO_0047619 UBERON:0001470 biolink:AnatomicalEntity glenohumeral joint The glenohumeral joint, commonly known as the shoulder joint, is a multiaxial synovial ball and socket joint and involves articulation between the glenoid fossa of the scapula (shoulder blade) and the head of the humerus (upper arm bone). [WP,unvetted]. go-plus.json articulatio humeri|humeroscapular joint|joint of shoulder|humeral joint|shoulder joint http://purl.obolibrary.org/obo/UBERON_0001470 GO:0047618 biolink:MolecularActivity acylagmatine amidase activity Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate. RHEA:15065|KEGG_REACTION:R01425|EC:3.5.1.40|MetaCyc:ACYLAGMATINE-AMIDASE-RXN go-plus.json acylagmatine amidohydrolase activity|benzoylagmatine amidohydrolase activity|acylagmatine deacylase activity http://purl.obolibrary.org/obo/GO_0047618 GO:0047617 biolink:MolecularActivity acyl-CoA hydrolase activity Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate. RHEA:16781|Reactome:R-HSA-5690042|Reactome:R-HSA-5690066|MetaCyc:ACYL-COA-HYDROLASE-RXN|EC:3.1.2.20|Reactome:R-HSA-5690043 go-plus.json acyl-CoA thiolesterase activity|acyl coenzyme A hydrolase activity|thioesterase B|acyl-CoA thioesterase activity|acyl-CoA thioesterase II activity|acyl-CoA thioesterase I activity|acyl coenzyme A thioesterase activity|thioesterase II http://purl.obolibrary.org/obo/GO_0047617 PR:000010335 biolink:Protein hepatocyte growth factor receptor An HGF/MSP receptor type tyrosine-protein kinase that is a translation product of the human MET gene or a 1:1 ortholog thereof. go-plus.json proto-oncogene c-Met|HGF receptor|scatter factor receptor|SF receptor|HGF/SF receptor|MET|tyrosine-protein kinase Met http://purl.obolibrary.org/obo/PR_000010335 GO:0047616 biolink:MolecularActivity acyl-CoA dehydrogenase (NADP+) activity Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+. MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN|EC:1.3.1.8|RHEA:22460 go-plus.json enoyl coenzyme A reductase activity|acyl-CoA:NADP+ 2-oxidoreductase activity|dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)|2-enoyl-CoA reductase activity|crotonyl coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_0047616 CHEBI:34008 biolink:ChemicalSubstance (R)-3-hydroxy-3-methyl-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_34008 GO:0047615 biolink:MolecularActivity actinomycin lactonase activity Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone. EC:3.1.1.39|MetaCyc:ACTINOMYCIN-LACTONASE-RXN go-plus.json actinomycin lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0047615 CHEBI:10036 biolink:ChemicalSubstance wax ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_10036 chebi_ph7_3 CHEBI:73690 biolink:ChemicalSubstance erythrose 4-phosphate/phosphoenolpyruvate family amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73690 UBERON:0001476 biolink:AnatomicalEntity deltoid A muscle of shoulder which attaches to the scapula, clavicle and humerus.[FMA,generalized] go-plus.json common shoulder muscle|musculus deltoideus|musculus deltoideus|deltoid muscle|deltoideus muscle|m. deltoideus|deltoideus http://purl.obolibrary.org/obo/UBERON_0001476 UBERON:0001479 biolink:AnatomicalEntity sesamoid bone A sesamoid element that is composed of bone tissue. go-plus.json sesamoid|ossa sesamoidea http://purl.obolibrary.org/obo/UBERON_0001479 UBERON:0001473 biolink:AnatomicalEntity lymphatic vessel A vessel that contains or conveys lymph, that originates as an interfibrillar or intercellular cleft or space in a tissue or organ, and that if small has no distinct walls or walls composed only of endothelial cells and if large resembles a vein in structure[BTO]. go-plus.json vas lymphaticum|lymph vessel http://purl.obolibrary.org/obo/UBERON_0001473 UBERON:0001472 biolink:AnatomicalEntity vaginal venous plexus The vaginal plexuses are placed at the sides of the vagina; they communicate with the uterine, vesical, and hemorrhoidal plexuses, and are drained by the vaginal veins, one on either side, into the hypogastric veins. [WP,unvetted]. go-plus.json venous vaginal plexus|plexus venosus vaginalis http://purl.obolibrary.org/obo/UBERON_0001472 CHEBI:73693 biolink:ChemicalSubstance ketone body go-plus.json http://purl.obolibrary.org/obo/CHEBI_73693 UBERON:0001474 biolink:AnatomicalEntity bone element Skeletal element that is composed of bone tissue. go-plus.json bone organ|bones|bone http://purl.obolibrary.org/obo/UBERON_0001474 CHEBI:48643 biolink:ChemicalSubstance (2Z)-2-hydroxypenta-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48643 CHEBI:24698 biolink:ChemicalSubstance hydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24698 CHEBI:24697 biolink:ChemicalSubstance hydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24697 UBERON:0001459 biolink:AnatomicalEntity skin of external ear A zone of skin that is part of a external ear [Automatically generated definition]. go-plus.json outer ear zone of skin|auricular region zone of skin|zone of skin of external ear|external ear skin|zone of skin of auricular region of head|zone of skin of outer ear|auricular region of head zone of skin|external ear zone of skin|zone of skin of auricular region|ear skin http://purl.obolibrary.org/obo/UBERON_0001459 UBERON:0001458 biolink:AnatomicalEntity skin of lip A zone of skin that is part of a lip [Automatically generated definition]. go-plus.json lip zone of skin|zone of skin of lip|lip skin|skin of lips http://purl.obolibrary.org/obo/UBERON_0001458 CHEBI:48649 biolink:ChemicalSubstance L-sorbopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_48649 chebi_ph7_3 CHEBI:24699 biolink:ChemicalSubstance hydroxyfluorenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_24699 GO:0047625 biolink:MolecularActivity adenosylmethionine cyclotransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone. MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN|EC:2.5.1.4|KEGG_REACTION:R00180|RHEA:21932 go-plus.json S-adenosyl-L-methionine alkyltransferase (cyclizing)|adenosylmethioninase activity|adenosyl methionine cyclotransferase activity http://purl.obolibrary.org/obo/GO_0047625 GO:0047624 biolink:MolecularActivity adenosine-tetraphosphatase activity Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate. EC:3.6.1.14|RHEA:24500|MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN go-plus.json adenosine-tetraphosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047624 GO:0047623 biolink:MolecularActivity adenosine-phosphate deaminase activity Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP. MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN|EC:3.5.4.17 go-plus.json adenine nucleotide deaminase activity|adenosine (phosphate) deaminase activity|adenosine-phosphate aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047623 GO:0047622 biolink:MolecularActivity adenosine nucleosidase activity Catalysis of the reaction: adenosine + H2O = D-ribose + adenine. RHEA:18669|MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN|EC:3.2.2.7 go-plus.json N-ribosyladenine ribohydrolase activity|ANase activity|adenosine hydrolase activity|adenosinase activity|adenosine ribohydrolase activity http://purl.obolibrary.org/obo/GO_0047622 GO:0047621 biolink:MolecularActivity acylpyruvate hydrolase activity Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate. EC:3.7.1.5|RHEA:19009|MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN|UM-BBD_reactionID:r1401 go-plus.json 3-acylpyruvate acylhydrolase activity http://purl.obolibrary.org/obo/GO_0047621 CHEBI:83027 biolink:ChemicalSubstance 16beta-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_83027 chebi_ph7_3 GO:0047620 biolink:MolecularActivity acylglycerol kinase activity Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate. MetaCyc:ACYLGLYCEROL-KINASE-RXN|EC:2.7.1.94|RHEA:19293|Reactome:R-HSA-5696074 go-plus.json monoglyceride phosphokinase activity|monoacylglycerol kinase (phosphorylating)|monoacylglycerol kinase activity|monoglyceride kinase activity|ATP:acylglycerol 3-phosphotransferase activity|MGK|sn-2-monoacylglycerol kinase activity http://purl.obolibrary.org/obo/GO_0047620 CHEBI:24693 biolink:ChemicalSubstance hydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24693 UBERON:0001460 biolink:AnatomicalEntity arm The part of the forelimb extending from the shoulder to the autopod[cjm]. go-plus.json brachium|upper extremity http://purl.obolibrary.org/obo/UBERON_0001460 CHEBI:10022 biolink:ChemicalSubstance deoxynivalenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_10022 chebi_ph7_3 GO:0047629 biolink:MolecularActivity ADP deaminase activity Catalysis of the reaction: ADP + H2O = IDP + NH3. EC:3.5.4.7|RHEA:12741|MetaCyc:ADP-DEAMINASE-RXN go-plus.json adenosinepyrophosphate deaminase activity|adenosine diphosphate deaminase activity|ADP aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047629 GO:0047628 biolink:MolecularActivity ADP-thymidine kinase activity Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate. RHEA:13413|EC:2.7.1.118|MetaCyc:ADP--THYMIDINE-KINASE-RXN go-plus.json ADP:dThd phosphotransferase activity|adenosine diphosphate-thymidine phosphotransferase activity|ADP:thymidine 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047628 GO:0047627 biolink:MolecularActivity adenylylsulfatase activity Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate. KEGG_REACTION:R00531|EC:3.6.2.1|RHEA:17041|MetaCyc:ADENYLYLSULFATASE-RXN go-plus.json adenylylsulphatase activity|adenylylsulfate sulfohydrolase activity|adenosine 5-phosphosulfate sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0047627 GO:0047626 biolink:MolecularActivity adenosylmethionine hydrolase activity Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+). RHEA:14645|KEGG_REACTION:R00175|EC:3.3.1.2|MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN go-plus.json S-adenosyl-L-methionine hydrolase activity|adenosylmethionine lyase activity|S-adenosylmethionine cleaving enzyme activity|methylmethionine-sulfonium-salt hydrolase activity|adenosyl methionine hydrolase activity http://purl.obolibrary.org/obo/GO_0047626 UBERON:0001466 biolink:AnatomicalEntity pedal digit A digit that is part of a pes (foot). go-plus.json pes digit|toe|hind_digit|hind digit|digitus pedis|digit of foot|digit of terminal segment of lower limb|foot digit|pedal digit (phalangeal portion) plus soft tissue|digitipedis|hindlimb digit|digiti pedis|digiti pedis http://purl.obolibrary.org/obo/UBERON_0001466 UBERON:0001465 biolink:AnatomicalEntity knee A segment of the hindlimb that corresponds to the joint connecting a hindlimb stylopod and zeugopod. go-plus.json knee region http://purl.obolibrary.org/obo/UBERON_0001465 UBERON:0001467 biolink:AnatomicalEntity shoulder A subdivision of the pectoral complex consisting of the structures in the region of the shoulder joint (which connects the humerus, scapula and clavicle). go-plus.json articulatio humeri|shoulder region http://purl.obolibrary.org/obo/UBERON_0001467 UBERON:0001461 biolink:AnatomicalEntity elbow The elbow is the region surrounding the elbow-joint-the ginglymus or hinge joint in the middle of the arm. Three bones form the elbow joint: the humerus of the upper arm, and the paired radius and ulna of the forearm. The bony prominence at the very tip of the elbow is the olecranon process of the ulna, and the inner aspect of the elbow is called the antecubital fossa. [WP,unvetted,human-specific]. go-plus.json elbow limb segment|articulatio cubiti|elbow region|cubital region http://purl.obolibrary.org/obo/UBERON_0001461 UBERON:0001464 biolink:AnatomicalEntity hip The hip region is located lateral to the gluteal region (i.e. the buttock), inferior to the iliac crest, and overlying the greater trochanter of the thigh bone. In adults, three of the bones of the pelvis have fused into the hip bone which forms part of the hip region. The hip joint, scientifically referred to as the acetabulofemoral joint (art. coxae), is the joint between the femur and acetabulum of the pelvis and its primary function is to support the weight of the body in both static (e.g. standing) and dynamic (e.g. walking or running) postures. [WP,modified]. go-plus.json regio coxae|hip region|coxa http://purl.obolibrary.org/obo/UBERON_0001464 CHEBI:24663 biolink:ChemicalSubstance hydroxy-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24663 CHEBI:24662 biolink:ChemicalSubstance hydroxy-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24662 CHEBI:24669 biolink:ChemicalSubstance hydroxy carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24669 UBERON:0001448 biolink:AnatomicalEntity metatarsal bone The metatarsus or metatarsal bones are a group of five long bones in the pes located between the tarsal bones of the hind- and mid-pes and the phalanges of the toes. Lacking individual names, the metatarsal bones are numbered from the medial side (side of big toe): the first, second, third, fourth, and fifth metatarsal. The metatarsals are analogous to the metacarpal bones of the manus. [WP,unvetted]. go-plus.json ossa metatarsi|ossa metatarsalia|metatarsal http://purl.obolibrary.org/obo/UBERON_0001448 UBERON:0001447 biolink:AnatomicalEntity tarsal bone A bone that is part of the tarsal skeleton. Examples: calcaneus, talus, centralia. go-plus.json bony tarsus|ossa tarsi|ankle bone|bone of ankle|bone of tarsal skeleton|tarsus osseus|ossa tarsalia|bone of tarsus|hind mesopodium|tarsal http://purl.obolibrary.org/obo/UBERON_0001447 CHEBI:48635 biolink:ChemicalSubstance fumagillin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48635 CHEBI:24668 biolink:ChemicalSubstance hydroxyacetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24668 CHEBI:48638 biolink:ChemicalSubstance 5'-phospho-(3'->5')-dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48638 UBERON:0001449 biolink:AnatomicalEntity phalanx of pes A phalanx that is part of a hindlimb autopod[Automatically generated definition]. go-plus.json toe phalanx|phalanges of hind digit|phalanx of pes|phalanx of foot digit|digitus pedis phalanx|foot digit phalanx|pedal phalanx|digital bone of pes|phalanx of toe|bone of toe|foot phalanx|phalanx of hind digit|phalanx of digit of foot|phalanx of digitus pedis http://purl.obolibrary.org/obo/UBERON_0001449 CHEBI:48637 biolink:ChemicalSubstance (3'->5')-dinucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48637 GO:0047636 biolink:MolecularActivity alanopine dehydrogenase activity Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate. MetaCyc:ALANOPINE-DEHYDROGENASE-RXN|EC:1.5.1.17|KEGG_REACTION:R00398|RHEA:17589 go-plus.json ADH|meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity|alanopine: NAD oxidoreductase activity|alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity|alanopine:NAD oxidoreductase activity|2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)|ALPDH http://purl.obolibrary.org/obo/GO_0047636 GO:0047635 biolink:MolecularActivity alanine-oxo-acid transaminase activity Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid. MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN|EC:2.6.1.12|RHEA:19953 go-plus.json alanine-oxo acid aminotransferase activity|L-alanine-alpha-keto acid aminotransferase activity|L-alanine:2-oxo-acid aminotransferase activity|alanine--oxo-acid aminotransferase activity|alanine-oxo-acid aminotransferase activity|leucine-alanine transaminase activity|alanine-keto acid aminotransferase activity http://purl.obolibrary.org/obo/GO_0047635 GO:0047634 biolink:MolecularActivity agmatine N4-coumaroyltransferase activity Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+). KEGG_REACTION:R01617|RHEA:13405|EC:2.3.1.64|MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN go-plus.json 4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity|agmatine coumaroyltransferase activity|p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity|4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity http://purl.obolibrary.org/obo/GO_0047634 GO:0047633 biolink:MolecularActivity agmatine kinase activity Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+). MetaCyc:AGMATINE-KINASE-RXN|KEGG_REACTION:R01417|RHEA:15953|EC:2.7.3.10 go-plus.json ATP:agmatine N4-phosphotransferase activity|phosphagen phosphokinase activity|ATP:agmatine 4-N-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047633 GO:0047632 biolink:MolecularActivity agmatine deiminase activity Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3. MetaCyc:AGMATINE-DEIMINASE-RXN|EC:3.5.3.12|RHEA:18037 go-plus.json agmatine amidinohydrolase|agmatine iminohydrolase activity http://purl.obolibrary.org/obo/GO_0047632 CHEBI:83039 biolink:ChemicalSubstance crustacean metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_83039 CHEBI:24661 biolink:ChemicalSubstance hydroxy-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24661 GO:0047631 biolink:MolecularActivity ADP-ribose diphosphatase activity Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate. Reactome:R-HSA-5696049|MetaCyc:RXN0-1441|Reactome:R-HSA-2393939|EC:3.6.1.13|RHEA:10412|Reactome:R-HSA-2393954 go-plus.json ADP-ribose pyrophosphatase activity|adenosine diphosphoribose pyrophosphatase activity|ADP-ribose phosphohydrolase activity|ADPribose pyrophosphatase activity|ADPR-PPase activity|ADPribose diphosphatase activity|ADP-ribose ribophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047631 CHEBI:83038 biolink:ChemicalSubstance Daphnia galeata metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_83038 GO:0047630 biolink:MolecularActivity ADP-phosphoglycerate phosphatase activity Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate. EC:3.1.3.28|KEGG_REACTION:R03969|MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN|RHEA:15861 go-plus.json ADPphosphoglycerate phosphatase activity|adenosine diphosphate phosphoglycerate phosphatase activity|3-(ADP)-2-phosphoglycerate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047630 CHEBI:83032 biolink:ChemicalSubstance 4-O-beta-D-glucosyl-trans-4-coumaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83032 GO:0047639 biolink:MolecularActivity alcohol oxidase activity Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2. MetaCyc:ALCOHOL-OXIDASE-RXN|EC:1.1.3.13|RHEA:19829 go-plus.json AOX activity|ethanol oxidase activity|alcohol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047639 GO:0047638 biolink:MolecularActivity albendazole monooxygenase activity Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+). EC:1.14.13.32|MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN|KEGG_REACTION:R03712|RHEA:10796 go-plus.json albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)|albendazole oxidase activity|albendazole sulfoxidase activity http://purl.obolibrary.org/obo/GO_0047638 GO:0047637 biolink:MolecularActivity alanylphosphatidylglycerol synthase activity Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol. MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN|EC:2.3.2.11|RHEA:20489 go-plus.json L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity|O-alanylphosphatidylglycerol synthase activity|alanyl phosphatidylglycerol synthetase activity http://purl.obolibrary.org/obo/GO_0047637 UBERON:0001457 biolink:AnatomicalEntity skin of eyelid A zone of skin that is part of a eyelid [Automatically generated definition]. go-plus.json eyelid zone of skin|zone of skin of eyelid|blepharon zone of skin|zone of skin of blepharon|eyelid skin http://purl.obolibrary.org/obo/UBERON_0001457 UBERON:0001456 biolink:AnatomicalEntity face A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc). go-plus.json visage|facia/facies http://purl.obolibrary.org/obo/UBERON_0001456 CHEBI:24676 biolink:ChemicalSubstance hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24676 CHEBI:48621 biolink:ChemicalSubstance Sep-tRNA(Sec) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48621 CHEBI:24675 biolink:ChemicalSubstance hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24675 CHEBI:24673 biolink:ChemicalSubstance hydroxybenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_24673 CHEBI:48622 biolink:ChemicalSubstance pGpG go-plus.json http://purl.obolibrary.org/obo/CHEBI_48622 UBERON:0001437 biolink:AnatomicalEntity epiphysis The head of a long bone that articulates with a neighboring skeletal element and is separated from the shaft by the epiphyseal plate until bone growth stops. At that time, the plate disappears and the head and shaft are united[MESH,modified]. go-plus.json long bone epiphysis|epiphyses|bone epiphysis|end of long bone http://purl.obolibrary.org/obo/UBERON_0001437 UBERON:0001436 biolink:AnatomicalEntity phalanx of manus A phalanx that is part of a forelimb autopod[Automatically generated definition]. go-plus.json phalanx of hand|phalanx of fore digit|phalanx of finger|hand phalanx|phalanx of digit of hand|phalanx of digitus manus|phalanges of fore digit|bone of finger|finger phalanx|manual phalanx|phalanx of hand digit|digitus manus phalanx|digital bone of manus|hand digit phalanx|phalanx of manual digit http://purl.obolibrary.org/obo/UBERON_0001436 CHEBI:24679 biolink:ChemicalSubstance hydroxybenzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24679 CHEBI:24678 biolink:ChemicalSubstance hydroxybenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_24678 UBERON:0001438 biolink:AnatomicalEntity metaphysis Zone of long bone that is between the epiphysis and diaphysis. Subdivision of diaphysis which forms the proximal or distal end of diaphysis next to the epiphysis; together with diaphysis proper, it constitutes the diaphysis. Examples: proximal metaphysis of humerus, distal metaphysis of femur.[FMA] go-plus.json diaphyseal end of long bone|long bone metaphysis|metaphyses http://purl.obolibrary.org/obo/UBERON_0001438 CHEBI:24677 biolink:ChemicalSubstance hydroxybenzophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24677 CHEBI:48626 biolink:ChemicalSubstance pyranoindolizinoquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48626 GO:0047647 biolink:MolecularActivity alkylacetylglycerophosphatase activity Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate. KEGG_REACTION:R03454|RHEA:18221|MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN|EC:3.1.3.59 go-plus.json 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity|1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity|alkylacetylglycerophosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0047647 GO:0047646 biolink:MolecularActivity alkanal monooxygenase (FMN-linked) activity Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light. MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN|RHEA:17181|EC:1.14.14.3 go-plus.json aldehyde monooxygenase activity|alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)|bacterial luciferase activity|vibrio fischeri luciferase activity http://purl.obolibrary.org/obo/GO_0047646 GO:0047645 biolink:MolecularActivity alkan-1-ol dehydrogenase (acceptor) activity Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor. RHEA:14685|MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN|EC:1.1.99.20 go-plus.json polyethylene glycol dehydrogenase activity|alkan-1-ol:(acceptor) oxidoreductase activity|alkan-1-ol:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047645 GO:0047644 biolink:MolecularActivity alizarin 2-beta-glucosyltransferase activity Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP. KEGG_REACTION:R03573|EC:2.4.1.103|MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:20677 go-plus.json uridine diphosphoglucose-alizarin glucosyltransferase activity|UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity|alizarin 2-b-glucosyltransferase activity|UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity http://purl.obolibrary.org/obo/GO_0047644 PR:000009345 biolink:Protein kit ligand A protein that is a translation product of the human KITLG gene or a 1:1 ortholog thereof. go-plus.json stem cell factor|SCF|Sl|hematopoietic growth factor KL|Kitl|mast cell growth factor|KITLG|Slf|steel factor|MGF|c-Kit ligand http://purl.obolibrary.org/obo/PR_000009345 GO:0047643 biolink:MolecularActivity alginate synthase activity Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1). MetaCyc:ALGINATE-SYNTHASE-RXN|EC:2.4.1.33|RHEA:46876 go-plus.json GDP-D-mannuronate:alginate D-mannuronyltransferase activity|mannuronosyl transferase activity http://purl.obolibrary.org/obo/GO_0047643 GO:0047642 biolink:MolecularActivity aldose beta-D-fructosyltransferase activity Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside. EC:2.4.1.162|MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN go-plus.json aldose b-D-fructosyltransferase activity|alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity http://purl.obolibrary.org/obo/GO_0047642 GO:0047641 biolink:MolecularActivity aldose-6-phosphate reductase (NADPH) activity Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH. EC:1.1.1.200|MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-NADPH-RXN|KEGG_REACTION:R00834|RHEA:20037 go-plus.json D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity|aldose-6-P reductase activity|A6PR|NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity|NADP-dependent aldose 6-phosphate reductase activity|alditol 6-phosphate:NADP 1-oxidoreductase activity|aldose-6-phosphate reductase activity|aldose 6-phosphate reductase activity http://purl.obolibrary.org/obo/GO_0047641 CHEBI:83048 biolink:ChemicalSubstance 4,4'-diaponeurosporenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83048 GO:0047640 biolink:MolecularActivity aldose 1-dehydrogenase activity Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH. MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.121|RHEA:15917 go-plus.json aldose dehydrogenase activity|dehydrogenase, D-aldohexose|D-aldose:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047640 CHEBI:83047 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83047 CHEBI:83045 biolink:ChemicalSubstance dodecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83045 CHEBI:10043 biolink:ChemicalSubstance wogonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_10043 CHEBI:83043 biolink:ChemicalSubstance 4,4'-diapolycopenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83043 CHEBI:83042 biolink:ChemicalSubstance undecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83042 CHEBI:10049 biolink:ChemicalSubstance XTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_10049 GO:0047649 biolink:MolecularActivity alkylglycerol kinase activity Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+). KEGG_REACTION:R04126|EC:2.7.1.93|MetaCyc:ALKYLGLYCEROL-KINASE-RXN|RHEA:16937 go-plus.json ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity|1-alkylglycerol kinase (phosphorylating)|ATP-alkylglycerol phosphotransferase activity|ATP:1-alkyl-sn-glycerol phosphotransferase activity|alkylglycerol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047649 GO:0047648 biolink:MolecularActivity alkylamidase activity Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium. KEGG_REACTION:R03620|MetaCyc:ALKYLAMIDASE-RXN|RHEA:20081|EC:3.5.1.39 go-plus.json N-methylhexanamide amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047648 UBERON:0001444 biolink:AnatomicalEntity subdivision of head go-plus.json head region|head subdivision|region of head http://purl.obolibrary.org/obo/UBERON_0001444 UBERON:0001443 biolink:AnatomicalEntity chest Subdivision of trunk proper, which is demarcated from the neck by the plane of the superior thoracic aperture and from the abdomen internally by the inferior surface of the diaphragm and externally by the costal margin and associated with the thoracic vertebral column and ribcage and from the back of the thorax by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines; together with the abdomen and the perineum, it constitutes the trunk proper[FMA]. go-plus.json anterolateral part of thorax|ventral part of thoracic region|thorax|pectus|front of thorax|thoracic body wall http://purl.obolibrary.org/obo/UBERON_0001443 UBERON:0001446 biolink:AnatomicalEntity fibula The major postaxial endochondral bone in the posterior zeugopod[Phenoscape]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001446 UBERON:0001445 biolink:AnatomicalEntity skeleton of pes Subdivision of skeleton that is the collection of all skeletal elements in a pes, which is the distal section of the posterior hindlimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the ankle, sole, and toes)[Phenoscape]. go-plus.json pes skeleton|posterior autopodium|foot region skeleton|skeleton of foot|posterior autopodium skeleton|foot skeleton|set of bones of foot|pes|pedal skeleton http://purl.obolibrary.org/obo/UBERON_0001445 UBERON:0001440 biolink:AnatomicalEntity forelimb skeleton The collection of all skeletal elements in a free forelimb region. Excludes the pectoral girdle go-plus.json skeleton of free upper limb|free upper limb skeleton|ossa membri superioris|skeleton of pectoral limb|bones of upper limb|wing skeleton|skeleton of upper limb|skeleton of forelimb|forelimb skeleton|set of bones of upper limb|upper limb skeleton|fore limb skeleton|pectoral limb skeleton http://purl.obolibrary.org/obo/UBERON_0001440 UBERON:0001442 biolink:AnatomicalEntity skeleton of manus Subdivision of skeleton that is the collection of all skeletal elements in a manus, which is the distal section of the anterior forelimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the wrist, palm, and fingers)[Phenoscape]. go-plus.json anterior autopodium|ossa manus|forelimb autopod skeleton|hand region skeleton|manual skeleton|bones of hand|skeleton of hand|hand skeleton|set of bones of hand|fore autopod skeleton|anterior autopodium skeleton|manus skeleton|manus http://purl.obolibrary.org/obo/UBERON_0001442 UBERON:0001441 biolink:AnatomicalEntity hindlimb skeleton Subdivision of skeleton consisting of all skeletal elements in an hindlimb region. go-plus.json skeleton of free lower limb|bones of lower limb|free lower limb skeleton|skeleton of lower limb|hind-limb skeleton|hindlimb skeleton|set of bones of lower limb|lower limb skeleton|ossa membri inferioris|hind limb skeleton http://purl.obolibrary.org/obo/UBERON_0001441 GO:0033009 biolink:CellularComponent nucleomorph A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively. Wikipedia:Nucleomorph go-plus.json http://purl.obolibrary.org/obo/GO_0033009 GO:0033008 biolink:BiologicalProcess positive regulation of mast cell activation involved in immune response Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response. go-plus.json positive regulation of mast cell activation during immune response http://purl.obolibrary.org/obo/GO_0033008 GO:0033007 biolink:BiologicalProcess negative regulation of mast cell activation involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response. go-plus.json negative regulation of mast cell activation during immune response http://purl.obolibrary.org/obo/GO_0033007 GO:0008049 biolink:BiologicalProcess male courtship behavior The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster. go-plus.json male courtship behaviour http://purl.obolibrary.org/obo/GO_0008049 GO:0008048 biolink:MolecularActivity calcium sensitive guanylate cyclase activator activity Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration. go-plus.json http://purl.obolibrary.org/obo/GO_0008048 GO:0008047 biolink:MolecularActivity enzyme activator activity Binds to and increases the activity of an enzyme. go-plus.json metalloenzyme activator activity http://purl.obolibrary.org/obo/GO_0008047 GO:0008046 biolink:MolecularActivity axon guidance receptor activity Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance. go-plus.json receptor activity involved in axon guidance http://purl.obolibrary.org/obo/GO_0008046 GO:0008045 biolink:BiologicalProcess motor neuron axon guidance The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. go-plus.json motoneuron axon guidance|motor axon pathfinding|motor axon guidance http://purl.obolibrary.org/obo/GO_0008045 GO:0008044 biolink:BiologicalProcess obsolete adult behavior (sensu Insecta) OBSOLETE. Behavior in a fully developed and mature organism, as seen in insects. go-plus.json adult behavior (sensu Insecta) http://purl.obolibrary.org/obo/GO_0008044 GO:0008043 biolink:CellularComponent intracellular ferritin complex A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains. go-plus.json http://purl.obolibrary.org/obo/GO_0008043 GO:0008053 biolink:BiologicalProcess mitochondrial fusion Merging of two or more mitochondria within a cell to form a single compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0008053 GO:0008052 biolink:BiologicalProcess sensory organ boundary specification The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained. go-plus.json sense organ boundary specification http://purl.obolibrary.org/obo/GO_0008052 CHEBI:58099 biolink:ChemicalSubstance dTDP-6-deoxy-L-talose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58099 chebi_ph7_3 GO:0008051 biolink:CellularComponent obsolete farnesyl-diphosphate farnesyl transferase complex OBSOLETE. A complex that possesses farnesyl-diphosphate farnesyl transferase activity. go-plus.json farnesyl-diphosphate farnesyl transferase complex http://purl.obolibrary.org/obo/GO_0008051 GO:0008050 biolink:BiologicalProcess female courtship behavior The behavior of a female, for the purpose of attracting a sexual partner. go-plus.json female courtship behaviour http://purl.obolibrary.org/obo/GO_0008050 CHEBI:58098 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-glucarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58098 chebi_ph7_3 CHEBI:58097 biolink:ChemicalSubstance morphine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58097 chebi_ph7_3 CHEBI:58096 biolink:ChemicalSubstance dolichyl D-xylosyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58096 chebi_ph7_3 CHEBI:58095 biolink:ChemicalSubstance L-phenylalanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58095 chebi_ph7_3 GO:0033006 biolink:BiologicalProcess regulation of mast cell activation involved in immune response Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response. go-plus.json regulation of mast cell activation during immune response http://purl.obolibrary.org/obo/GO_0033006 GO:0033005 biolink:BiologicalProcess positive regulation of mast cell activation Any process that activates or increases the frequency, rate, or extent of mast cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_0033005 GO:0033004 biolink:BiologicalProcess negative regulation of mast cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_0033004 GO:0033003 biolink:BiologicalProcess regulation of mast cell activation Any process that modulates the frequency, rate, or extent of mast cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_0033003 GO:0033002 biolink:BiologicalProcess muscle cell proliferation The expansion of a muscle cell population by cell division. go-plus.json myocyte proliferation http://purl.obolibrary.org/obo/GO_0033002 GO:0033001 biolink:CellularComponent Fc-gamma receptor III complex A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG. go-plus.json immunoglobulin G receptor complex|IgG receptor complex|FcgRIII complex http://purl.obolibrary.org/obo/GO_0033001 GO:0033000 biolink:CellularComponent Fc-gamma receptor I complex A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG. go-plus.json immunoglobulin G receptor complex|IgG receptor complex|FcgRI complex http://purl.obolibrary.org/obo/GO_0033000 CHEBI:58093 biolink:ChemicalSubstance homoserinium lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_58093 chebi_ph7_3 CHEBI:58092 biolink:ChemicalSubstance N-phosphocreatinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58092 chebi_ph7_3 GO:0008059 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008059 CHEBI:58091 biolink:ChemicalSubstance deacetylisoipecoside(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58091 chebi_ph7_3 GO:0008058 biolink:BiologicalProcess ocellus pigment granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus. go-plus.json ocellus pigment granule organization and biogenesis|ocellus pigment granule organisation http://purl.obolibrary.org/obo/GO_0008058 CHEBI:58090 biolink:ChemicalSubstance L-cysteate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58090 chebi_ph7_3 GO:0008057 biolink:BiologicalProcess eye pigment granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye. go-plus.json eye pigment granule organization and biogenesis|eye pigment granule organisation http://purl.obolibrary.org/obo/GO_0008057 GO:0008056 biolink:BiologicalProcess ocellus development The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects. go-plus.json http://purl.obolibrary.org/obo/GO_0008056 GO:0008055 biolink:BiologicalProcess ocellus pigment biosynthetic process The chemical reactions and pathways resulting in the formation of ocellus pigments, general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates. go-plus.json ocellus pigment anabolism|ocellus pigment biosynthesis|ocellus pigment synthesis|ocellus pigment formation http://purl.obolibrary.org/obo/GO_0008055 GO:0008054 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008054 GO:0008064 biolink:BiologicalProcess regulation of actin polymerization or depolymerization Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. go-plus.json http://purl.obolibrary.org/obo/GO_0008064 GO:0008063 biolink:BiologicalProcess Toll signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json Toll signalling pathway|Tl signaling pathway|Tl signalling pathway http://purl.obolibrary.org/obo/GO_0008063 CHEBI:58089 biolink:ChemicalSubstance 5-phosphonato-D-ribosylaminium(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58089 chebi_ph7_3 CHEBI:58088 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 3-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58088 chebi_ph7_3 GO:0008062 biolink:BiologicalProcess eclosion rhythm The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn. go-plus.json http://purl.obolibrary.org/obo/GO_0008062 CHEBI:58087 biolink:ChemicalSubstance N-(3-carboxylatopropionyl)-LL-2,6-diaminopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58087 chebi_ph7_3 GO:0008061 biolink:MolecularActivity chitin binding Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. go-plus.json http://purl.obolibrary.org/obo/GO_0008061 goslim_drosophila GO:0008060 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008060 CHEBI:58086 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58086 chebi_ph7_3 CHEBI:58085 biolink:ChemicalSubstance 2-isopropylmaleate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58085 chebi_ph7_3 CHEBI:58083 biolink:ChemicalSubstance glycerol 2-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58083 chebi_ph7_3 GO:0008029 biolink:MolecularActivity pentraxin receptor activity Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json pentaxin receptor http://purl.obolibrary.org/obo/GO_0008029 GO:0008028 biolink:MolecularActivity monocarboxylic acid transmembrane transporter activity Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group. Reactome:R-HSA-5624211|Reactome:R-HSA-429749|Reactome:R-HSA-9645220|Reactome:R-HSA-433698 go-plus.json monocarboxylate carrier|prostaglandin/thromboxane transporter activity http://purl.obolibrary.org/obo/GO_0008028 CHEBI:58082 biolink:ChemicalSubstance O-(1->4)-alpha-L-dihydrostreptosylstreptidine 6-phosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58082 chebi_ph7_3 CHEBI:58081 biolink:ChemicalSubstance dTDP-D-galacturonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58081 chebi_ph7_3 GO:0008027 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008027 GO:0008026 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008026 CHEBI:58080 biolink:ChemicalSubstance N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58080 chebi_ph7_3 GO:0008025 biolink:MolecularActivity obsolete diazepam binding inhibitor activity OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters. go-plus.json DBI|diazepam binding inhibitor activity|diazepam-binding inhibitor activity http://purl.obolibrary.org/obo/GO_0008025 GO:0008024 biolink:CellularComponent cyclin/CDK positive transcription elongation factor complex A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit. go-plus.json positive transcription elongation factor complex b http://purl.obolibrary.org/obo/GO_0008024 GO:0008023 biolink:CellularComponent transcription elongation factor complex Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0008023 goslim_pir GO:0008022 biolink:MolecularActivity protein C-terminus binding Binding to a protein C-terminus, the end of a peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. go-plus.json carboxy-terminus binding|carboxylate-terminal binding|carboxyl-terminal binding|carboxylate-terminus binding|carboxyl-terminus binding|C-terminal binding|COOH-terminus binding|COOH-terminal binding|C-terminal end binding|carboxy-terminal binding http://purl.obolibrary.org/obo/GO_0008022 goslim_chembl GO:0008021 biolink:CellularComponent synaptic vesicle A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. Wikipedia:Synaptic_vesicle|NIF_Subcellular:sao1071221672 go-plus.json docked vesicle http://purl.obolibrary.org/obo/GO_0008021 goslim_synapse CHEBI:58079 biolink:ChemicalSubstance butanoyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58079 chebi_ph7_3 GO:0008031 biolink:MolecularActivity eclosion hormone activity The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis. go-plus.json http://purl.obolibrary.org/obo/GO_0008031 GO:0008030 biolink:MolecularActivity neuronal pentraxin receptor activity Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json neuronal pentaxin receptor http://purl.obolibrary.org/obo/GO_0008030 CHEBI:58078 biolink:ChemicalSubstance CDP-3,6-dideoxy-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58078 chebi_ph7_3 CHEBI:58077 biolink:ChemicalSubstance bis-gamma-glutamylcystinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58077 chebi_ph7_3 CHEBI:58075 biolink:ChemicalSubstance 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58075 chebi_ph7_3 CHEBI:58074 biolink:ChemicalSubstance D-nopalinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58074 chebi_ph7_3 CHEBI:58072 biolink:ChemicalSubstance carbon monoxide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58072 chebi_ph7_3 CHEBI:73603 biolink:ChemicalSubstance 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73603 chebi_ph7_3 CHEBI:58071 biolink:ChemicalSubstance mono(2-ethylhexyl) phthalate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58071 chebi_ph7_3 GO:0008039 biolink:BiologicalProcess synaptic target recognition The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses. go-plus.json neuronal targeting http://purl.obolibrary.org/obo/GO_0008039 goslim_synapse CHEBI:58070 biolink:ChemicalSubstance dehydroascorbide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58070 chebi_ph7_3 GO:0008038 biolink:BiologicalProcess neuron recognition The process in which a neuronal cell in a multicellular organism interprets its surroundings. go-plus.json neuronal cell recognition http://purl.obolibrary.org/obo/GO_0008038 GO:0008037 biolink:BiologicalProcess cell recognition The process in which a cell in an organism interprets its surroundings. go-plus.json recognition of surroundings by cell http://purl.obolibrary.org/obo/GO_0008037 goslim_pir GO:0008036 biolink:MolecularActivity diuretic hormone receptor activity Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0008036 GO:0008035 biolink:MolecularActivity high-density lipoprotein particle binding Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE. go-plus.json HDL binding http://purl.obolibrary.org/obo/GO_0008035 GO:0008034 biolink:MolecularActivity obsolete lipoprotein binding OBSOLETE. Binding to a conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. go-plus.json lipoprotein binding http://purl.obolibrary.org/obo/GO_0008034 UBERON:3010706 biolink:AnatomicalEntity lateral line nucleus go-plus.json http://purl.obolibrary.org/obo/UBERON_3010706 GO:0008033 biolink:BiologicalProcess tRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. go-plus.json tRNA maturation http://purl.obolibrary.org/obo/GO_0008033 goslim_yeast GO:0008032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008032 GO:0008042 biolink:MolecularActivity obsolete iron-sulfur electron transfer carrier OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system. go-plus.json iron-sulfur electron transfer carrier|iron-sulphur electron transfer carrier|ferredoxin http://purl.obolibrary.org/obo/GO_0008042 CHEBI:58068 biolink:ChemicalSubstance 2-hydroxy-6-oxohexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58068 chebi_ph7_3 CHEBI:58067 biolink:ChemicalSubstance (3Z,5S)-3-(1-oxidoethylidene)-5-{[4-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}pyrrolidine-2,4-dione(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58067 chebi_ph7_3 GO:0008041 biolink:MolecularActivity obsolete storage protein of fat body (sensu Insecta) OBSOLETE. (Was not defined before being made obsolete). go-plus.json storage protein of fat body (sensu Insecta) http://purl.obolibrary.org/obo/GO_0008041 GO:0008040 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008040 CHEBI:58066 biolink:ChemicalSubstance L-glutamic 5-semialdehyde zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58066 chebi_ph7_3 CHEBI:58065 biolink:ChemicalSubstance homocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58065 chebi_ph7_3 CHEBI:58064 biolink:ChemicalSubstance taurocyamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58064 chebi_ph7_3 CHEBI:58062 biolink:ChemicalSubstance rosmarinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58062 chebi_ph7_3 CHEBI:58061 biolink:ChemicalSubstance salutaridinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58061 chebi_ph7_3 DDANAT:0010001 biolink:OntologyClass Dictyostelium discoideum anatomical structure Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the Dictyostelium discoideum genome. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0010001 CHEBI:58069 biolink:ChemicalSubstance CDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58069 chebi_ph7_3 CHEBI:73610 biolink:ChemicalSubstance Met-Ala go-plus.json http://purl.obolibrary.org/obo/CHEBI_73610 GO:0008009 biolink:MolecularActivity chemokine activity The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0008009 goslim_chembl GO:0008008 biolink:CellularComponent obsolete membrane attack complex protein beta2 chain OBSOLETE. (Was not defined before being made obsolete). go-plus.json membrane attack complex protein beta2 chain http://purl.obolibrary.org/obo/GO_0008008 GO:0008007 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008007 GO:0008006 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008006 GO:0008005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008005 GO:0008004 biolink:CellularComponent obsolete lamina reticularis OBSOLETE. A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0008004 CHEBI:73619 biolink:ChemicalSubstance 3-methylthioaspartic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73619 GO:0008003 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008003 GO:0008002 biolink:CellularComponent obsolete lamina lucida OBSOLETE. The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina. Wikipedia:Lamina_lucida go-plus.json http://purl.obolibrary.org/obo/GO_0008002 GO:0008001 biolink:MolecularActivity obsolete fibrinogen OBSOLETE. (Was not defined before being made obsolete). go-plus.json fibrinogen http://purl.obolibrary.org/obo/GO_0008001 CHEBI:58057 biolink:ChemicalSubstance geranyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58057 chebi_ph7_3 CHEBI:58056 biolink:ChemicalSubstance 2-methylideneglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58056 chebi_ph7_3 CHEBI:58055 biolink:ChemicalSubstance 4,5-dioxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58055 chebi_ph7_3 CHEBI:58053 biolink:ChemicalSubstance IMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58053 chebi_ph7_3 CHEBI:58052 biolink:ChemicalSubstance UDP-alpha-D-glucuronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58052 chebi_ph7_3 CHEBI:58051 biolink:ChemicalSubstance 4,5-dihydroxyphthalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58051 chebi_ph7_3 CHEBI:58050 biolink:ChemicalSubstance dolichyl N-acetyl-alpha-D-glucosaminyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58050 chebi_ph7_3 CHEBI:34083 biolink:ChemicalSubstance {1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho}ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_34083 CHEBI:34086 biolink:ChemicalSubstance {1-O-hexadecanoyl-2-O-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho}serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_34086 CHEBI:58059 biolink:ChemicalSubstance oxidized Cypridina luciferin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58059 chebi_ph7_3 CHEBI:58058 biolink:ChemicalSubstance D-lysopine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58058 chebi_ph7_3 CHEBI:73621 biolink:ChemicalSubstance 3-methylthioaspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73621 CHEBI:73620 biolink:ChemicalSubstance 3-methylthioaspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73620 chebi_ph7_3 CHEBI:73625 biolink:ChemicalSubstance 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73625 CHEBI:73624 biolink:ChemicalSubstance 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73624 GO:0008019 biolink:MolecularActivity obsolete macrophage receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json macrophage receptor activity http://purl.obolibrary.org/obo/GO_0008019 GO:0008018 biolink:MolecularActivity obsolete structural protein of chorion (sensu Drosophila) OBSOLETE. (Was not defined before being made obsolete). go-plus.json structural protein of chorion (sensu Drosophila) http://purl.obolibrary.org/obo/GO_0008018 CHEBI:73626 biolink:ChemicalSubstance 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73626 chebi_ph7_3 GO:0008017 biolink:MolecularActivity microtubule binding Binding to a microtubule, a filament composed of tubulin monomers. Reactome:R-HSA-9614343 go-plus.json microtubule/chromatin interaction|microtubule severing activity http://purl.obolibrary.org/obo/GO_0008017 GO:0008016 biolink:BiologicalProcess regulation of heart contraction Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. go-plus.json regulation of cardiac contraction http://purl.obolibrary.org/obo/GO_0008016 GO:0008015 biolink:BiologicalProcess blood circulation The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. go-plus.json hemolymph circulation http://purl.obolibrary.org/obo/GO_0008015 goslim_pir GO:0008014 biolink:MolecularActivity obsolete calcium-dependent cell adhesion molecule activity OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions. go-plus.json calcium-dependent cell adhesion molecule activity|cadherin http://purl.obolibrary.org/obo/GO_0008014 GO:0008013 biolink:MolecularActivity beta-catenin binding Binding to a catenin beta subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0008013 GO:0008012 biolink:MolecularActivity structural constituent of adult chitin-based cuticle The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster. go-plus.json structural constituent of adult cuticle http://purl.obolibrary.org/obo/GO_0008012 GO:0008011 biolink:MolecularActivity structural constituent of pupal chitin-based cuticle The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster. go-plus.json structural constituent of pupal cuticle http://purl.obolibrary.org/obo/GO_0008011 GO:0008010 biolink:MolecularActivity structural constituent of chitin-based larval cuticle The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster. go-plus.json structural constituent of larval cuticle http://purl.obolibrary.org/obo/GO_0008010 GO:0008020 biolink:MolecularActivity G protein-coupled photoreceptor activity Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json G protein coupled photoreceptor activity|G-protein coupled photoreceptor activity|photoreceptor activity, G-protein coupled http://purl.obolibrary.org/obo/GO_0008020 CHEBI:58046 biolink:ChemicalSubstance 3,5-dibromo-4-oxidobenzonitrile(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58046 chebi_ph7_3 CHEBI:58045 biolink:ChemicalSubstance L-isoleucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58045 chebi_ph7_3 CHEBI:58044 biolink:ChemicalSubstance 2,5-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58044 chebi_ph7_3 CHEBI:58043 biolink:ChemicalSubstance nucleoside 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58043 chebi_ph7_3 CHEBI:58042 biolink:ChemicalSubstance guanidinoethyl methyl phosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58042 chebi_ph7_3 CHEBI:143979 biolink:ChemicalSubstance 5'-end phospho-guanosine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_143979 chebi_ph7_3 CHEBI:58041 biolink:ChemicalSubstance heparosan N-sulfate L-iduronate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58041 chebi_ph7_3 CHEBI:58040 biolink:ChemicalSubstance dimethylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58040 chebi_ph7_3 CHEBI:58048 biolink:ChemicalSubstance L-asparagine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58048 chebi_ph7_3 CHEBI:58047 biolink:ChemicalSubstance thiomorpholine-3-carboxylic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58047 chebi_ph7_3 CHEBI:58035 biolink:ChemicalSubstance 1D-3-ammmonio-1-guanidiniumyl-1,3-dideoxy-scyllo-inositol(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58035 chebi_ph7_3 CHEBI:58034 biolink:ChemicalSubstance flavonol 3-O-(6-O-malonyl-beta-D-glucoside)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58034 chebi_ph7_3 CHEBI:58033 biolink:ChemicalSubstance 2-phosphonatoglycolate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58033 chebi_ph7_3 CHEBI:58032 biolink:ChemicalSubstance anhydrotetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58032 chebi_ph7_3 CHEBI:58031 biolink:ChemicalSubstance 2-(3-amino-3-carboxypropyl)-L-histidine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58031 chebi_ph7_3 CHEBI:58030 biolink:ChemicalSubstance 5-formyl-2-hydroxyhepta-2,4-dienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58030 chebi_ph7_3 CHEBI:143966 biolink:ChemicalSubstance (2S)-homocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_143966 CHEBI:58039 biolink:ChemicalSubstance N-methylputrescinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58039 chebi_ph7_3 CHEBI:58038 biolink:ChemicalSubstance Photinus luciferin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58038 chebi_ph7_3 CHEBI:34063 biolink:ChemicalSubstance naphthalene-1,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34063 chebi_ph7_3 CHEBI:58037 biolink:ChemicalSubstance O-demethylpuromycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58037 chebi_ph7_3 CHEBI:34080 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34080 CHEBI:58024 biolink:ChemicalSubstance deoxylimonoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58024 chebi_ph7_3 CHEBI:58023 biolink:ChemicalSubstance (3,5-diiodo-4-oxidophenyl)pyruvate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58023 chebi_ph7_3 CHEBI:58022 biolink:ChemicalSubstance 10-oxocaprate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58022 chebi_ph7_3 CHEBI:58021 biolink:ChemicalSubstance glucotropeolin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58021 chebi_ph7_3 CHEBI:58020 biolink:ChemicalSubstance 2-aminoacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58020 CHEBI:34071 biolink:ChemicalSubstance 1-arachidonoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34071 chebi_ph7_3 CHEBI:58029 biolink:ChemicalSubstance cysteaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58029 chebi_ph7_3 CHEBI:58028 biolink:ChemicalSubstance 6-O-sulfonato-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->3)-1-O-alkyl-2-O-acylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_58028 chebi_ph7_3 CHEBI:58027 biolink:ChemicalSubstance glyceraldehyde 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58027 chebi_ph7_3 CHEBI:58026 biolink:ChemicalSubstance 8-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58026 chebi_ph7_3 CHEBI:58025 biolink:ChemicalSubstance octopaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58025 chebi_ph7_3 GO:0072573 biolink:BiologicalProcess tolerance induction to lipopolysaccharide Tolerance induction directed at lipopolysaccharide antigens. go-plus.json tolerance induction to LPS|tolerance induction to endotoxin http://purl.obolibrary.org/obo/GO_0072573 GO:0072572 biolink:MolecularActivity poly-ADP-D-ribose binding Binding to polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring. go-plus.json pADPr binding|poly-ADP-ribose binding http://purl.obolibrary.org/obo/GO_0072572 GO:0072571 biolink:MolecularActivity mono-ADP-D-ribose binding Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment. go-plus.json mADPr binding|mono-ADP-ribose binding http://purl.obolibrary.org/obo/GO_0072571 GO:0072570 biolink:MolecularActivity ADP-D-ribose binding Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment. go-plus.json ADP-ribose binding http://purl.obolibrary.org/obo/GO_0072570 GO:0106313 biolink:MolecularActivity methylenetetrahydrofolate reductase NADPH activity Catalysis of the reaction: 5-methyltetrahydrofolate + NADP + = 5,10-methylenetetrahydrofolate + NADPH + H+. RHEA:19817 go-plus.json http://purl.obolibrary.org/obo/GO_0106313 GO:0106312 biolink:MolecularActivity methylenetetrahydrofolate reductase NADH activity Catalysis of the reaction: 5-methyltetrahydrofolate + NAD + = 5,10-methylenetetrahydrofolate + NADH + H+. RHEA:19821 go-plus.json http://purl.obolibrary.org/obo/GO_0106312 GO:0106311 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0106311 GO:0106310 biolink:MolecularActivity protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. RHEA:17989 go-plus.json http://purl.obolibrary.org/obo/GO_0106310 GO:0106317 biolink:MolecularActivity methane monooxygenase NADH activity Catalysis of the reaction: methane + NADH + H+ + O2 = methanol + NAD+ + H2O. EC:1.14.13.25|RHEA:13637 go-plus.json http://purl.obolibrary.org/obo/GO_0106317 UBERON:2001053 biolink:AnatomicalEntity future internal carotid artery go-plus.json PICA|primitive internal carotid artery http://purl.obolibrary.org/obo/UBERON_2001053 GO:0106316 biolink:MolecularActivity nitrite reductase NADH activity Catalysis of the reaction: ammonium hydroxide + 3 NAD+ + H2O = nitrite + 3 NADH + 3 H+. RHEA:24628 go-plus.json http://purl.obolibrary.org/obo/GO_0106316 GO:0106314 biolink:MolecularActivity nitrite reductase NADPH activity Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+. RHEA:24632 go-plus.json http://purl.obolibrary.org/obo/GO_0106314 GO:0106319 biolink:MolecularActivity (R)-limonene 1,2-monooxygenase NADH activity Catalysis of the reaction: (4R)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4R)-limonene-1,2-epoxide. EC:1.14.13.107|RHEA:26093 go-plus.json http://purl.obolibrary.org/obo/GO_0106319 GO:0106318 biolink:MolecularActivity methane monooxygenase NADPH activity Catalysis of the reaction: methane + NADPH + H+ + O2 = methanol + NADP+ + H2O. EC:1.14.13.25|RHEA:13641 go-plus.json http://purl.obolibrary.org/obo/GO_0106318 GO:0072579 biolink:BiologicalProcess glycine receptor clustering The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0072579 GO:0072578 biolink:BiologicalProcess neurotransmitter-gated ion channel clustering The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0072578 GO:0072577 biolink:BiologicalProcess endothelial cell apoptotic process Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. go-plus.json programmed cell death of endothelial cells by apoptosis|killing of endothelial cells|endothelial cell programmed cell death by apoptosis|apoptosis of endothelial cells|endothelial cell apoptosis|programmed cell death, endothelial cells http://purl.obolibrary.org/obo/GO_0072577 GO:0072576 biolink:BiologicalProcess liver morphogenesis The process in which the anatomical structures of the liver are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0072576 GO:0072575 biolink:BiologicalProcess epithelial cell proliferation involved in liver morphogenesis The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver. go-plus.json http://purl.obolibrary.org/obo/GO_0072575 GO:0072574 biolink:BiologicalProcess hepatocyte proliferation The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. go-plus.json http://purl.obolibrary.org/obo/GO_0072574 GO:0106320 biolink:MolecularActivity (R)-limonene 1,2-monooxygenase NADPH activity Catalysis of the reaction: (4R)-limonene + NADPH + H+ + O2 = NADP+ + H2O + (4R)-limonene-1,2-epoxide. RHEA:26097|EC:1.14.13.107 go-plus.json http://purl.obolibrary.org/obo/GO_0106320 GO:0072562 biolink:CellularComponent blood microparticle A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids. go-plus.json cell membrane microparticle http://purl.obolibrary.org/obo/GO_0072562 GO:0072561 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072561 GO:0072560 biolink:BiologicalProcess type B pancreatic cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. go-plus.json pancreatic beta cell maturation|pancreatic B cell maturation http://purl.obolibrary.org/obo/GO_0072560 GO:0106324 biolink:MolecularActivity (S)-limonene 1,2-monooxygenase NADH activity Catalysis of the reaction: (4S)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4S)-limonene-1,2-epoxide. RHEA:26089 go-plus.json http://purl.obolibrary.org/obo/GO_0106324 GO:0106323 biolink:MolecularActivity (S)-limonene 1,2-monooxygenase NADPH activity Catalysis of the reaction: (4S)-limonene + NADPH+= + H+ + O2 = NADP+ + H2O + (4S)-limonene-1,2-epoxide. RHEA:26085 go-plus.json http://purl.obolibrary.org/obo/GO_0106323 GO:0106322 biolink:MolecularActivity S-(hydroxymethyl)glutathione dehydrogenase NAD activity Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+. RHEA:19985|EC:1.1.1.284 go-plus.json http://purl.obolibrary.org/obo/GO_0106322 GO:0106321 biolink:MolecularActivity S-(hydroxymethyl)glutathione dehydrogenase NADP activity Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+. RHEA:19981|EC:1.1.1.284 go-plus.json http://purl.obolibrary.org/obo/GO_0106321 GO:0106328 biolink:MolecularActivity acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP. RHEA:46884|EC:2.4.1.147 go-plus.json http://purl.obolibrary.org/obo/GO_0106328 GO:0106327 biolink:MolecularActivity acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP. RHEA:46880|EC:2.4.1.147 go-plus.json http://purl.obolibrary.org/obo/GO_0106327 GO:0106326 biolink:MolecularActivity acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP. EC:2.4.1.148|RHEA:56192 go-plus.json http://purl.obolibrary.org/obo/GO_0106326 GO:0106325 biolink:MolecularActivity acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP. RHEA:56188|EC:2.4.1.148 go-plus.json http://purl.obolibrary.org/obo/GO_0106325 GO:0106329 biolink:MolecularActivity L-phenylalaine oxidase activity Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+). RHEA:61240 go-plus.json http://purl.obolibrary.org/obo/GO_0106329 GO:0072569 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072569 GO:0072568 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072568 GO:0072567 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 2 production The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json SCYB2 production|MIP-2 production|MIP2 production|CXCL2 production http://purl.obolibrary.org/obo/GO_0072567 gocheck_do_not_annotate GO:0072566 biolink:BiologicalProcess chemokine (C-X-C motif) ligand 1 production The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CXCL1 production|KC production|SCYB1 production|keratinocyte derived chemokine production http://purl.obolibrary.org/obo/GO_0072566 gocheck_do_not_annotate GO:0072565 biolink:BiologicalProcess endothelial microparticle formation The cellular component organization process in which microparticles bud off from an endothelial cell. go-plus.json endothelial microparticle generation|endothelial microparticle release http://purl.obolibrary.org/obo/GO_0072565 GO:0072564 biolink:BiologicalProcess blood microparticle formation The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. go-plus.json microparticle generation|microparticle release http://purl.obolibrary.org/obo/GO_0072564 GO:0072563 biolink:CellularComponent endothelial microparticle A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072563 GO:0072595 biolink:BiologicalProcess maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. go-plus.json maintenance of protein localization to organelle|maintenance of protein localisation to organelle http://purl.obolibrary.org/obo/GO_0072595 GO:0106331 biolink:MolecularActivity sialate 4-O-acetylesterase activity Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate. EC:3.1.1.53|RHEA:25564 go-plus.json http://purl.obolibrary.org/obo/GO_0106331 GO:0106330 biolink:MolecularActivity sialate 9-O-acetylesterase activity Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate. EC:3.1.1.53|RHEA:22600 go-plus.json http://purl.obolibrary.org/obo/GO_0106330 GO:0072594 biolink:BiologicalProcess establishment of protein localization to organelle The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. go-plus.json establishment of protein localisation to organelle http://purl.obolibrary.org/obo/GO_0072594 GO:0072593 biolink:BiologicalProcess reactive oxygen species metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. go-plus.json reactive oxygen species metabolism|ROS metabolic process http://purl.obolibrary.org/obo/GO_0072593 GO:0072592 biolink:BiologicalProcess oxygen metabolic process The chemical reactions and pathways involving diatomic oxygen (O2). go-plus.json diatomic oxygen metabolic process|oxygen metabolism http://purl.obolibrary.org/obo/GO_0072592 GO:0072591 biolink:MolecularActivity citrate-L-glutamate ligase activity Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0072591 GO:0106335 biolink:MolecularActivity tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity Catalysis of the reaction: carboxymethyluridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine. RHEA:43208|EC:2.1.1.229 go-plus.json http://purl.obolibrary.org/obo/GO_0106335 GO:0072590 biolink:MolecularActivity N-acetyl-L-aspartate-L-glutamate ligase activity Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate. Reactome:R-HSA-8942575 go-plus.json http://purl.obolibrary.org/obo/GO_0072590 GO:0106334 biolink:MolecularActivity 3'-deoxyribose phosphate lyase activity Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate. go-plus.json 3'-dRP lyase|3'-dRP lyase activity http://purl.obolibrary.org/obo/GO_0106334 GO:0106333 biolink:CellularComponent subcortical maternal complex Comprised of at least NLRP5, OOEP, TLE6, and KHDC3/KHDC3L with evidence of additional SCMC-associated proteins that interact with one or multiple members of the core complex. go-plus.json SCMC http://purl.obolibrary.org/obo/GO_0106333 UBERON:2001073 biolink:AnatomicalEntity axial vasculature go-plus.json http://purl.obolibrary.org/obo/UBERON_2001073 GO:0106332 biolink:MolecularActivity ds/ssDNA junction-specific dsDNA endonuclease activity Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction. go-plus.json http://purl.obolibrary.org/obo/GO_0106332 GO:0106339 biolink:MolecularActivity tRNA (cytidine 32-2'-O)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + cytosine32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0106339 GO:0106336 biolink:BiologicalProcess yolk syncytial layer development The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm. go-plus.json YSL development http://purl.obolibrary.org/obo/GO_0106336 GO:0072599 biolink:BiologicalProcess establishment of protein localization to endoplasmic reticulum The directed movement of a protein to a specific location in the endoplasmic reticulum. go-plus.json establishment of protein localization to ER|establishment of protein localization in endoplasmic reticulum|establishment of protein localisation to ER|establishment of protein localisation to endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0072599 GO:0072598 biolink:BiologicalProcess protein localization to chloroplast A process in which a protein is transported to, or maintained at, a location in a chloroplast. go-plus.json protein localisation to chloroplast http://purl.obolibrary.org/obo/GO_0072598 GO:0072597 biolink:BiologicalProcess maintenance of protein location in chloroplast Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0072597 GO:0072596 biolink:BiologicalProcess establishment of protein localization to chloroplast The directed movement of a protein to a specific location in a chloroplast. go-plus.json establishment of protein localisation to chloroplast http://purl.obolibrary.org/obo/GO_0072596 GO:0072584 biolink:BiologicalProcess caveolin-mediated endocytosis An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers. go-plus.json caveolae-dependent endocytosis|caveolin-dependent endocytosis|caveolae-mediated endocytosis http://purl.obolibrary.org/obo/GO_0072584 GO:0106342 biolink:BiologicalProcess omega-hydroxyceramide biosynthetic process The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide. go-plus.json http://purl.obolibrary.org/obo/GO_0106342 GO:0106341 biolink:MolecularActivity omega-hydroxyceramide transacylase activity Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine. RHEA:55264 go-plus.json http://purl.obolibrary.org/obo/GO_0106341 GO:0072583 biolink:BiologicalProcess clathrin-dependent endocytosis An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles. go-plus.json clathrin-dependent endocytosis|clathrin coated pit-dependent endocytosis|clathrin-mediated endocytosis|CME http://purl.obolibrary.org/obo/GO_0072583 GO:0072582 biolink:MolecularActivity 17-beta-hydroxysteroid dehydrogenase (NADP+) activity Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+. RHEA:24616 go-plus.json http://purl.obolibrary.org/obo/GO_0072582 GO:0106340 biolink:MolecularActivity tRNA (guanosine 32-2'-O)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 32 in tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0106340 GO:0072581 biolink:BiologicalProcess protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P). go-plus.json http://purl.obolibrary.org/obo/GO_0072581 GO:0072580 biolink:BiologicalProcess bacterial-type EF-P lysine modification The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P). go-plus.json EF-P modification pathway http://purl.obolibrary.org/obo/GO_0072580 GO:0106346 biolink:MolecularActivity snRNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0106346 GO:0106345 biolink:MolecularActivity glyoxylate reductase activity Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H. go-plus.json http://purl.obolibrary.org/obo/GO_0106345 GO:0106344 biolink:MolecularActivity 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H(+) + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase]. RHEA:65756 go-plus.json 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP http://purl.obolibrary.org/obo/GO_0106344 GO:0106343 biolink:MolecularActivity glutarate dioxygenase activity Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2. EC:1.14.11.64|RHEA:13821 go-plus.json http://purl.obolibrary.org/obo/GO_0106343 GO:0106349 biolink:BiologicalProcess snRNA methylation The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0106349 GO:0106348 biolink:MolecularActivity U2 snRNA adenosine m6 methytransferase activity Catalysis of the reaction: a adenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-adenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+. go-plus.json http://purl.obolibrary.org/obo/GO_0106348 GO:0106347 biolink:MolecularActivity U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+. RHEA:62672 go-plus.json http://purl.obolibrary.org/obo/GO_0106347 GO:0072589 biolink:CellularComponent box H/ACA scaRNP complex A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs. go-plus.json nucleoplasmic box H/ACA RNP pseudouridylase complex http://purl.obolibrary.org/obo/GO_0072589 GO:0072588 biolink:CellularComponent box H/ACA RNP complex A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex. go-plus.json box H/ACA snoRNP pseudouridylase complex|sRNP complex http://purl.obolibrary.org/obo/GO_0072588 GO:0072587 biolink:MolecularActivity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. go-plus.json http://purl.obolibrary.org/obo/GO_0072587 GO:0072586 biolink:MolecularActivity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. go-plus.json http://purl.obolibrary.org/obo/GO_0072586 GO:0072585 biolink:MolecularActivity xanthosine nucleotidase activity Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine. RHEA:27994|MetaCyc:RXN0-363 go-plus.json xanthosine ribohydrolase activity http://purl.obolibrary.org/obo/GO_0072585 GO:0106302 biolink:MolecularActivity arachidonic acid 8,9-epoxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid. RHEA:64984 go-plus.json http://purl.obolibrary.org/obo/GO_0106302 GO:0106301 biolink:MolecularActivity arachidonic acid 5,6-epoxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-5,6-epoxyeicosatrienoic acid. RHEA:49936 go-plus.json http://purl.obolibrary.org/obo/GO_0106301 GO:0106300 biolink:BiologicalProcess protein-DNA covalent cross-linking repair The removal of covalent cross-link between DNA and a protein. go-plus.json resolution of protein-DNA covalent cross-linking http://purl.obolibrary.org/obo/GO_0106300 GO:0106306 biolink:MolecularActivity protein serine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate. RHEA:20629|EC:3.1.3.16 go-plus.json http://purl.obolibrary.org/obo/GO_0106306 GO:0106305 biolink:BiologicalProcess mannogen catabolic process The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania. go-plus.json beta-1,2-mannan catabolic process|mannogen degradation|beta-1,2-mannan catabolism|mannogen catabolism|mannogen breakdown http://purl.obolibrary.org/obo/GO_0106305 GO:0106304 biolink:BiologicalProcess mannogen biosynthetic process The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania. go-plus.json mannogen anabolism|mannogen synthesis|mannogen formation|beta-1,2-mannan biosynthetic process|mannogen biosynthesis http://purl.obolibrary.org/obo/GO_0106304 GO:0106303 biolink:BiologicalProcess mannogen metabolic process The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania. go-plus.json mannogen metabolism|beta-1,2-mannan metabolic process http://purl.obolibrary.org/obo/GO_0106303 GO:0106309 biolink:MolecularActivity progesterone 21-hydroxylase activity Catalysis of the reaction: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:50304 go-plus.json http://purl.obolibrary.org/obo/GO_0106309 GO:0106307 biolink:MolecularActivity protein threonine phosphatase activity Catalysis of the reaction: protein threonine phosphate + H2O = protein threonine + phosphate. RHEA:47004|EC:3.1.3.16 go-plus.json http://purl.obolibrary.org/obo/GO_0106307 OBA:1000227 biolink:OntologyClass lens of camera-type eye quality The quality of a lens of camera-type eye. go-plus.json quality of lens of camera-type eye http://purl.obolibrary.org/obo/OBA_1000227 CHEBI:24646 biolink:ChemicalSubstance hydroquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_24646 chebi_ph7_3 CHEBI:24644 biolink:ChemicalSubstance HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_24644 GO:0047537 biolink:MolecularActivity 2-aminohexanoate transaminase activity Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate. MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN|EC:2.6.1.67|RHEA:23600 go-plus.json leucine L-norleucine: 2-oxoglutarate aminotransferase activity|norleucine aminotransferase activity|L-2-aminohexanoate:2-oxoglutarate aminotransferase activity|norleucine (leucine) aminotransferase activity|norleucine transaminase activity|2-aminohexanoate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047537 GO:0047536 biolink:MolecularActivity 2-aminoadipate transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate. Reactome:R-HSA-70952|MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R01939|Reactome:R-HSA-508561|EC:2.6.1.39|RHEA:12601 go-plus.json glutamic-ketoadipic transaminase activity|2-aminoadipate aminotransferase activity|glutamate-alpha-ketoadipate transaminase activity|2-aminoadipic aminotransferase activity|L-2-aminoadipate:2-oxoglutarate aminotransferase activity|alpha-aminoadipate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047536 GO:0047535 biolink:MolecularActivity 2-alkyn-1-ol dehydrogenase activity Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH. RHEA:19101|MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN|EC:1.1.1.165|KEGG_REACTION:R03963 go-plus.json 2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047535 GO:0047534 biolink:MolecularActivity 2-acetolactate mutase activity Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate. RHEA:16361|EC:5.4.99.3|MetaCyc:2-ACETOLACTATE-MUTASE-RXN go-plus.json acetohydroxy acid isomerase activity|acetolactate mutase activity|2-acetolactate methylmutase activity http://purl.obolibrary.org/obo/GO_0047534 GO:0047533 biolink:MolecularActivity 2,5-dioxovalerate dehydrogenase (NADP+) activity Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+. RHEA:11296|EC:1.2.1.26|MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN go-plus.json 2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity|alpha-ketoglutaric semialdehyde dehydrogenase activity|2-oxoglutarate semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047533 NCBITaxon:155616 biolink:OrganismalEntity Tremellomycetes go-plus.json Heterobasidiomycetes|Tremellomycetidae http://purl.obolibrary.org/obo/NCBITaxon_155616 GO:0047532 biolink:MolecularActivity 2,5-dioxopiperazine hydrolase activity Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine. RHEA:21808|MetaCyc:25-DIOXOPIPERAZINE-HYDROLASE-RXN|EC:3.5.2.13|KEGG_REACTION:R03810 go-plus.json cyclo(glycylglycine) hydrolase activity|cyclo(Gly-Gly) hydrolase activity|2,5-dioxopiperazine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047532 GO:0047531 biolink:MolecularActivity 2,5-diaminovalerate transaminase activity Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate. MetaCyc:25-DIAMINOVALERATE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R03248|EC:2.6.1.8|RHEA:16017 go-plus.json diamino-acid transaminase activity|2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity|diamino-acid aminotransferase activity|2,5-diaminovalerate aminotransferase activity|diamino acid aminotransferase activity http://purl.obolibrary.org/obo/GO_0047531 GO:0047530 biolink:MolecularActivity 2,4-diaminopentanoate dehydrogenase activity Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+. EC:1.4.1.12|MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN go-plus.json 2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)|2,4-diaminopentanoic acid C4 dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047530 GO:0047539 biolink:MolecularActivity 2-deoxyglucosidase activity Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol. EC:3.2.1.112|MetaCyc:2-DEOXYGLUCOSIDASE-RXN|RHEA:15317 go-plus.json 2-deoxy-alpha-D-glucosidase activity|2-deoxy-alpha-glucosidase activity|2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity http://purl.obolibrary.org/obo/GO_0047539 GO:0047538 biolink:MolecularActivity 2-carboxy-D-arabinitol-1-phosphatase activity Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate. KEGG_REACTION:R04167|MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN|RHEA:17837|EC:3.1.3.63 go-plus.json 2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity|2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity|2-carboxyarabinitol 1-phosphatase activity http://purl.obolibrary.org/obo/GO_0047538 CHEBI:24648 biolink:ChemicalSubstance hydroxamic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_24648 GO:0047540 biolink:MolecularActivity 2-enoate reductase activity Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+. EC:1.3.1.31|RHEA:10200|MetaCyc:2-ENOATE-REDUCTASE-RXN go-plus.json butanoate:NAD+ delta2-oxidoreductase activity|enoate reductase activity http://purl.obolibrary.org/obo/GO_0047540 CHEBI:24654 biolink:ChemicalSubstance hydroxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24654 CHEBI:48600 biolink:ChemicalSubstance arsenate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48600 CHEBI:24651 biolink:ChemicalSubstance hydroxides go-plus.json http://purl.obolibrary.org/obo/CHEBI_24651 CHEBI:24658 biolink:ChemicalSubstance hydroxy-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24658 CHEBI:48604 biolink:ChemicalSubstance carnitinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48604 chebi_ph7_3 GO:0047548 biolink:MolecularActivity 2-methyleneglutarate mutase activity Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate. KEGG_REACTION:R03908|EC:5.4.99.4|RHEA:13793|MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN go-plus.json 2-methyleneglutarate carboxy-methylenemethylmutase activity|alpha-methyleneglutarate mutase activity http://purl.obolibrary.org/obo/GO_0047548 GO:0047547 biolink:MolecularActivity 2-methylcitrate dehydratase activity Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O. EC:4.2.1.79|MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN|KEGG_REACTION:R04424|RHEA:17725 go-plus.json (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]|2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity|prpD|2-methylcitrate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047547 GO:0047546 biolink:MolecularActivity 2-hydroxypyridine 5-monooxygenase activity Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O. KEGG_REACTION:R03206|RHEA:16973|MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN|EC:1.14.99.26 go-plus.json 2-hydroxypyridine oxygenase activity|2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating) http://purl.obolibrary.org/obo/GO_0047546 GO:0047545 biolink:MolecularActivity 2-hydroxyglutarate dehydrogenase activity Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. Reactome:R-HSA-880050|RHEA:21252|EC:1.1.99.2|MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN go-plus.json alpha-hydroxyglutarate dehydrogenase activity|L-alpha-hydroxyglutarate dehydrogenase activity|L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase|(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase|hydroxyglutaric dehydrogenase activity|alpha-hydroxyglutarate oxidoreductase activity|(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase|alpha-hydroxyglutarate dehydrogenase (NAD+ specific) http://purl.obolibrary.org/obo/GO_0047545 GO:0047544 biolink:MolecularActivity 2-hydroxybiphenyl 3-monooxygenase activity Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+). UM-BBD_reactionID:r1423|RHEA:11996|KEGG_REACTION:R03964|MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN|EC:1.14.13.44 go-plus.json 2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating) http://purl.obolibrary.org/obo/GO_0047544 CHEBI:24650 biolink:ChemicalSubstance hydroxamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24650 GO:0047543 biolink:MolecularActivity 2-hexadecenal reductase activity Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH. EC:1.3.1.27|MetaCyc:2-HEXADECENAL-REDUCTASE-RXN|RHEA:12444|KEGG_REACTION:R02463 go-plus.json hexadecanal: NADP+ oxidoreductase activity|hexadecanal:NADP+ delta2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047543 GO:0047542 biolink:MolecularActivity 2-furoyl-CoA dehydrogenase activity Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+). MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN|KEGG_REACTION:R02987|RHEA:21480|EC:1.3.99.8 go-plus.json 2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)|2-furoyl coenzyme A hydroxylase activity|2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)|furoyl-CoA hydroxylase activity|2-furoyl coenzyme A dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047542 GO:0047541 biolink:MolecularActivity 2-furoate-CoA ligase activity Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+). MetaCyc:2-FUROATE--COA-LIGASE-RXN|KEGG_REACTION:R02986|EC:6.2.1.31|RHEA:19269 go-plus.json 2-furoate:CoA ligase (AMP-forming)|2-furoyl coenzyme A synthetase activity http://purl.obolibrary.org/obo/GO_0047541 GO:0047549 biolink:MolecularActivity 2-nitrophenol 2-monooxygenase activity Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite. EC:1.14.13.31|KEGG_REACTION:R00828|UM-BBD_reactionID:r1494|MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN|RHEA:19457 go-plus.json 2-nitrophenol oxygenase activity|nitrophenol oxygenase activity|2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming) http://purl.obolibrary.org/obo/GO_0047549 CHEBI:24659 biolink:ChemicalSubstance hydroxy-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24659 GO:0047551 biolink:MolecularActivity 2-oxoaldehyde dehydrogenase (NAD+) activity Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+. EC:1.2.1.23|Wikipedia:2-oxoaldehyde_dehydrogenase_(NAD+)|RHEA:22276|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN go-plus.json NAD-dependent alpha-ketoaldehyde dehydrogenase activity|2-ketoaldehyde dehydrogenase|alpha-ketoaldehyde dehydrogenase activity|NAD-linked alpha-ketoaldehyde dehydrogenase activity|methylglyoxal dehydrogenase activity|2-oxoaldehyde dehydrogenase (NAD+)|2-oxoaldehyde:NAD+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047551 CHEBI:24621 biolink:ChemicalSubstance hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24621 GO:0047550 biolink:MolecularActivity 2-oxoadipate reductase activity Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH. MetaCyc:2-OXOADIPATE-REDUCTASE-RXN|EC:1.1.1.172|KEGG_REACTION:R01932|RHEA:14793 go-plus.json alpha-ketoadipate reductase activity|2-hydroxyadipate:NAD+ 2-oxidoreductase activity|2-ketoadipate reductase activity http://purl.obolibrary.org/obo/GO_0047550 GO:0047559 biolink:MolecularActivity 3-dehydro-L-gulonate 2-dehydrogenase activity Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN|EC:1.1.1.130 go-plus.json 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity|3-keto-L-gulonate dehydrogenase activity|2,3-diketo-L-gulonate reductase activity|3-ketogulonate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047559 GO:0047558 biolink:MolecularActivity 3-cyanoalanine hydratase activity Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+). RHEA:15385|MetaCyc:3-CYANOALANINE-HYDRATASE-RXN|EC:4.2.1.65|KEGG_REACTION:R01267 go-plus.json L-asparagine hydro-lyase (3-cyanoalanine-forming)|beta-CNA nitrilase activity|beta-cyanoalanine hydrolase activity|L-asparagine hydro-lyase activity|beta-cyanoalanine hydratase activity|beta-CNAla hydrolase activity http://purl.obolibrary.org/obo/GO_0047558 GO:0047557 biolink:MolecularActivity 3-aci-nitropropanoate oxidase activity Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite. RHEA:22372|KEGG_REACTION:R01609|MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN|EC:1.7.3.5 go-plus.json propionate-3-nitronate oxidase activity|3-aci-nitropropanoate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047557 GO:0047556 biolink:MolecularActivity 3,4-dihydroxyphthalate decarboxylase activity Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2). MetaCyc:34-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|EC:4.1.1.69|UM-BBD_reactionID:r1447|KEGG_REACTION:R01634|RHEA:18601 go-plus.json 3,4-dihydroxyphthalate 2-decarboxylase activity|3,4-dihydroxyphthalate carboxy-lyase activity|3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming) http://purl.obolibrary.org/obo/GO_0047556 GO:0047555 biolink:MolecularActivity 3',5'-cyclic-GMP phosphodiesterase activity Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. Reactome:R-HSA-74059|Reactome:R-HSA-4086392|MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-418456|EC:3.1.4.35|RHEA:16957 go-plus.json 3',5' cyclic-GMP phosphodiesterase activity|3',5'-cyclic-GMP 5'-nucleotidohydrolase activity|guanosine cyclic 3',5'-phosphate phosphodiesterase activity|cyclic guanosine 3',5'-monophosphate phosphodiesterase activity|cGMP-specific phosphodiesterase activity|cyclic guanosine 3',5'-phosphate phosphodiesterase activity|cyclic GMP phosphodiesterase activity|cyclic 3',5'-GMP phosphodiesterase activity|cGMP-PDE|cGMP phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0047555 GO:0047554 biolink:MolecularActivity 2-pyrone-4,6-dicarboxylate lactonase activity Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+). MetaCyc:RXN-2462|EC:3.1.1.57|RHEA:10644|KEGG_REACTION:R04277 go-plus.json 2-pyrone-4,6-dicarboxylate lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0047554 GO:0047553 biolink:MolecularActivity 2-oxoglutarate synthase activity Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin. RHEA:17297|MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN|EC:1.2.7.3 go-plus.json alpha-ketoglutarate-ferredoxin oxidoreductase activity|2-ketoglutarate ferredoxin oxidoreductase activity|2-oxoglutarate ferredoxin oxidoreductase activity|alpha-ketoglutarate synthase activity|KGOR activity|2-oxoglutarate:ferredoxin oxidoreductase activity|2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)|2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0047553 GO:0047552 biolink:MolecularActivity 2-oxoaldehyde dehydrogenase (NADP+) activity Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+. EC:1.2.1.49|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN|RHEA:18129 go-plus.json methylglyoxal dehydrogenase activity|NADP-dependent alpha-ketoaldehyde dehydrogenase activity|NADP-linked alpha-ketoaldehyde dehydrogenase activity|2-oxoaldehyde:NADP+ 2-oxidoreductase activity|2-ketoaldehyde dehydrogenase|alpha-ketoaldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047552 UBERON:0001491 biolink:AnatomicalEntity wrist joint A joint connecting the forelimb zeugopod skeleton with the carpal skeleton. go-plus.json radiocarpal joint|joint of wrist|joint of carpal region|carpal region joint http://purl.obolibrary.org/obo/UBERON_0001491 UBERON:0001490 biolink:AnatomicalEntity elbow joint A joint that connects the forelimb zeugopod and stylopod skeletons[Obol]. go-plus.json joint of elbow|joint of cubital region|articulatio cubiti|cubital region joint http://purl.obolibrary.org/obo/UBERON_0001490 UBERON:0001493 biolink:AnatomicalEntity axillary nerve The axillary nerve is a nerve of the human body, that comes off the posterior cord of the brachial plexus at the level of the axilla (armpit) and carries nerve fibers from C5 and C6. The axillary nerve travels through the quadrangular space with the posterior circumflex humeral artery and vein. [WP,unvetted]. go-plus.json circumflex nerve|auxillery nerve|circumflex humeral nerve|nervus axillaris http://purl.obolibrary.org/obo/UBERON_0001493 GO:0072519 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072519 GO:0072518 biolink:MolecularActivity Rho-dependent protein serine/threonine kinase activity Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. go-plus.json Rho-associated protein kinase activity|ROCK kinase activity http://purl.obolibrary.org/obo/GO_0072518 GO:0072517 biolink:CellularComponent host cell viral assembly compartment A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place. go-plus.json host cell viral assembly site|virion assembly compartment|viral assembly compartment|viral assembly site|host cell virion assembly compartment http://purl.obolibrary.org/obo/GO_0072517 GO:0072516 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072516 UBERON:0001499 biolink:AnatomicalEntity muscle of arm A muscle organ that is part of an arm [Automatically generated definition]. go-plus.json arm muscle system|arm muscle|arm skeletal muscle|arm skeletal muscle tissue|upper arm / lower arm muscle|muscle of upper arm or lower arm http://purl.obolibrary.org/obo/UBERON_0001499 GO:0072515 biolink:BiologicalProcess trehalose transport in response to desiccation The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water. go-plus.json http://purl.obolibrary.org/obo/GO_0072515 CHEBI:24628 biolink:ChemicalSubstance imidazolidine-2,4-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_24628 GO:0072514 biolink:BiologicalProcess trehalose transport in response to water deprivation The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water. go-plus.json http://purl.obolibrary.org/obo/GO_0072514 UBERON:0001498 biolink:AnatomicalEntity muscle of pes Any muscle organ that is part of a pes [Automatically generated definition]. go-plus.json foot muscle organ|muscle of foot|foot muscle|muscle organ of foot http://purl.obolibrary.org/obo/UBERON_0001498 GO:0072513 biolink:BiologicalProcess positive regulation of secondary heart field cardioblast proliferation Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract). go-plus.json negative regulation of second heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_0072513 GO:0072512 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072512 GO:0072511 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072511 GO:0072510 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072510 UBERON:0001497 biolink:AnatomicalEntity muscle of pelvic girdle Any muscle organ that is part of a pelvic girdle [Automatically generated definition]. go-plus.json muscle organ of girdle-pelvic|pelvic girdle muscle organ|pelvic girdle skeletal muscle|muscle organ of pelvic girdle|girdle-pelvic muscle organ|pelvic girdle muscle|muscle organ of pelvic girdle bone http://purl.obolibrary.org/obo/UBERON_0001497 UBERON:0001496 biolink:AnatomicalEntity ascending aorta The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia] go-plus.json aorta ascendens|ascending thoracic aorta|pars ascendens aortae|pars ascendens aortae http://purl.obolibrary.org/obo/UBERON_0001496 CHEBI:24632 biolink:ChemicalSubstance hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_24632 GO:0047562 biolink:MolecularActivity 3-hydroxyaspartate aldolase activity Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate. EC:4.1.3.14|KEGG_REACTION:R00478|RHEA:14377|MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN go-plus.json erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity|erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity|erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)|erythro-beta-hydroxyaspartate glycine-lyase activity|erythro-beta-hydroxyaspartate aldolase activity http://purl.obolibrary.org/obo/GO_0047562 GO:0047561 biolink:MolecularActivity 3-hydroxyanthranilate oxidase activity Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2). KEGG_REACTION:R02666|RHEA:17245|EC:1.10.3.5|MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN go-plus.json 3-hydroxyanthranilic acid oxidase activity|3-hydroxyanthranilate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047561 CHEBI:24631 biolink:ChemicalSubstance hydrazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24631 GO:0047560 biolink:MolecularActivity 3-dehydrosphinganine reductase activity Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH. Reactome:R-HSA-428123|RHEA:22640|MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN|EC:1.1.1.102|KEGG_REACTION:R02978 go-plus.json 3-ketosphinganine reductase activity|D-3-dehydrosphinganine reductase activity|3-oxosphinganine reductase activity|3-oxosphinganine:NADPH oxidoreductase activity|D-3-oxosphinganine:B-NADPH oxidoreductase activity|D-3-oxosphinganine reductase activity|DSR activity|KTS reductase activity|D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047560 CHEBI:24636 biolink:ChemicalSubstance proton go-plus.json http://purl.obolibrary.org/obo/CHEBI_24636 GO:0047569 biolink:MolecularActivity 3-oxoadipate CoA-transferase activity Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA. EC:2.8.3.6|MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN|RHEA:12048|UM-BBD_reactionID:r1050 go-plus.json succinyl-CoA:3-oxoadipate CoA-transferase activity|3-oxoadipate coenzyme A-transferase activity|3-oxoadipate succinyl-CoA transferase activity|beta-ketoadipate:succinyl-CoA transferase activity http://purl.obolibrary.org/obo/GO_0047569 GO:0047568 biolink:MolecularActivity 3-oxo-5-beta-steroid 4-dehydrogenase activity Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor. MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN|RHEA:24172|EC:1.3.99.6 go-plus.json 3-oxo-5beta-steroid 4-dehydrogenase activity|3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity|delta4-3-ketosteroid 5-beta-reductase activity|3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047568 GO:0047567 biolink:MolecularActivity 3-methyleneoxindole reductase activity Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH. MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN|RHEA:20257|KEGG_REACTION:R03930|EC:1.3.1.17 go-plus.json 3-methyloxindole:NADP+ oxidoreductase activity|3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047567 GO:0047566 biolink:MolecularActivity 3-ketovalidoxylamine C-N-lyase activity Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+). RHEA:22768|KEGG_REACTION:R04367|MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN|EC:4.3.3.1 go-plus.json 4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity|3-ketovalidoxylamine A C-N-lyase activity|p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity|4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming] http://purl.obolibrary.org/obo/GO_0047566 GO:0047565 biolink:MolecularActivity 3-hydroxypropionate dehydrogenase (NAD+) activity Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH. MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN|RHEA:13357|KEGG_REACTION:R01608|EC:1.1.1.59 go-plus.json 3-hydroxypropanoate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047565 GO:0047564 biolink:MolecularActivity 3-hydroxycyclohexanone dehydrogenase activity Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione. RHEA:15905|KEGG_REACTION:R03212|MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN|EC:1.1.99.26 go-plus.json 3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047564 GO:0047563 biolink:MolecularActivity 3-hydroxybenzoate 2-monooxygenase activity Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O. RHEA:14193|EC:1.14.99.23|MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R01508 go-plus.json 3-hydroxybenzoate 2-hydroxylase activity|3-HBA-2-hydroxylase activity|3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating) http://purl.obolibrary.org/obo/GO_0047563 UBERON:0001480 biolink:AnatomicalEntity proximal carpal bone A carpal bone that proximally_connected_to a forelimb zeugopod skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001480 UBERON:0001482 biolink:AnatomicalEntity muscle of shoulder Any muscle organ that is part of a shoulder [Automatically generated definition]. go-plus.json shoulder muscle organ|shoulder muscle|muscle organ of shoulder http://purl.obolibrary.org/obo/UBERON_0001482 GO:0072509 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072509 GO:0072508 biolink:BiologicalProcess trivalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072508 GO:0072507 biolink:BiologicalProcess divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072507 GO:0072506 biolink:BiologicalProcess trivalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072506 GO:0072505 biolink:BiologicalProcess divalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072505 CHEBI:10003 biolink:ChemicalSubstance ribostamycin sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_10003 UBERON:0001488 biolink:AnatomicalEntity ankle joint A joint that connects the hindlimb autopod and zeugopod skeletons. go-plus.json talotibial joint|hock joint|mortise joint|talocrural articulation|hock|gambrel|talocrural joint http://purl.obolibrary.org/obo/UBERON_0001488 GO:0072504 biolink:BiologicalProcess cellular trivalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of trivalent cations at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072504 UBERON:0001487 biolink:AnatomicalEntity pes joint A skeletal joint that is part of a pes [Automatically generated definition]. go-plus.json articulationes pedis|pedal joint|joints of foot|hind limb autopod joint|joint of terminal segment of free lower limb|foot joint|joint of pes http://purl.obolibrary.org/obo/UBERON_0001487 GO:0072503 biolink:BiologicalProcess cellular divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072503 GO:0072502 biolink:BiologicalProcess cellular trivalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072502 GO:0072501 biolink:BiologicalProcess cellular divalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072501 UBERON:0001489 biolink:AnatomicalEntity manus joint A skeletal joint that is part of a manus (hand) [Automatically generated definition]. go-plus.json articulationes manus|joint of manus|joint of hand|joint of terminal segment of free upper limb|hand joint|manual joint http://purl.obolibrary.org/obo/UBERON_0001489 GO:0072500 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor http://purl.obolibrary.org/obo/GO_0072500 UBERON:0001484 biolink:AnatomicalEntity articular capsule An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]. go-plus.json fibrous capsule of joint|capsula articularis|joint capsule|joint fibrous capsule|capsulae articulares http://purl.obolibrary.org/obo/UBERON_0001484 UBERON:0001483 biolink:AnatomicalEntity skin of shoulder A zone of skin that is part of a shoulder region. go-plus.json shoulder skin|zone of skin of shoulder|shoulder zone of skin http://purl.obolibrary.org/obo/UBERON_0001483 UBERON:0001485 biolink:AnatomicalEntity knee joint The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation[WP,unvetted]. go-plus.json joint of knee|articulatio genus http://purl.obolibrary.org/obo/UBERON_0001485 GO:0047573 biolink:MolecularActivity 4-acetamidobutyrate deacetylase activity Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate. MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN|RHEA:15897|EC:3.5.1.63 go-plus.json 4-acetamidobutanoate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047573 GO:0106352 biolink:MolecularActivity aspartate dehydrogenase NADP activity Catalysis of the reaction: L-aspartate + H2O + NADP+ = oxaloacetate + NH3 + NADPH+ H+. RHEA:11784 go-plus.json http://purl.obolibrary.org/obo/GO_0106352 GO:0047572 biolink:MolecularActivity 3-phosphoglycerate phosphatase activity Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate. EC:3.1.3.38|KEGG_REACTION:R01511|RHEA:12412|MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN go-plus.json D-3-phosphoglycerate phosphatase activity|D-glycerate-3-phosphate phosphohydrolase activity|3-PGA phosphatase activity http://purl.obolibrary.org/obo/GO_0047572 GO:0106351 biolink:MolecularActivity aspartate dehydrogenase NAD activity Catalysis of the reaction: L-aspartate + H2O + NAD+ = oxaloacetate + NH3 + NADH+ H+. RHEA:11788 go-plus.json http://purl.obolibrary.org/obo/GO_0106351 GO:0047571 biolink:MolecularActivity 3-oxosteroid 1-dehydrogenase activity Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor. UM-BBD_enzymeID:e0712|EC:1.3.99.4|RHEA:13329|MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN go-plus.json 1-ene-dehydrogenase activity|delta1-steroid reductase activity|3-oxosteroid:(acceptor) delta1-oxidoreductase activity|3-ketosteroid-1-en-dehydrogenase activity|4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity|3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity|3-oxosteroid delta1-dehydrogenase activity|3-oxosteroid:acceptor delta1-oxidoreductase activity|delta1-dehydrogenase activity|3-ketosteroid-delta1-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047571 GO:0106350 biolink:MolecularActivity octaprenyl pyrophosphate synthase activity Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate. RHEA:27798|EC:2.5.1.90 go-plus.json http://purl.obolibrary.org/obo/GO_0106350 GO:0047570 biolink:MolecularActivity 3-oxoadipate enol-lactonase activity Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate. EC:3.1.1.24|RHEA:10184|MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN go-plus.json 3-ketoadipate enol-lactonase activity|carboxymethylbutenolide lactonase activity|4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity|beta-ketoadipate enol-lactone hydrolase activity|beta-ketoadipic enol-lactone hydrolase activity|3-oxoadipic enol-lactone hydrolase activity http://purl.obolibrary.org/obo/GO_0047570 SO:0000001 biolink:SequenceFeature region A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. go-plus.json sequence http://purl.obolibrary.org/obo/SO_0000001 SOFA GO:0106357 biolink:MolecularActivity glycerol-1-phosphate dehydrogenase [NAD+] activity Catalysis of the reaction: NAD+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADH. RHEA:21412 go-plus.json http://purl.obolibrary.org/obo/GO_0106357 GO:0106356 biolink:MolecularActivity 4-hydroxybenzoate 3-monooxygenase [NADPH] activity Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+. RHEA:19477 go-plus.json http://purl.obolibrary.org/obo/GO_0106356 GO:0106355 biolink:MolecularActivity 4-hydroxybenzoate 3-monooxygenase [NADH] activity Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+. RHEA:19473 go-plus.json http://purl.obolibrary.org/obo/GO_0106355 GO:0106354 biolink:BiologicalProcess tRNA surveillance The set of processes involved in identifying and degrading defective or aberrant tRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0106354 GO:0106359 biolink:MolecularActivity 2-hydroxyacyl-CoA lyase activity Catalysis of the reaction: A 2-hydroxyacyl-CoA = formyl-CoA + a propanol. go-plus.json http://purl.obolibrary.org/obo/GO_0106359 GO:0047579 biolink:MolecularActivity 4-hydroxymandelate oxidase activity Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2). EC:1.1.3.19|MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN|RHEA:15833|KEGG_REACTION:R02673 go-plus.json L-4-hydroxymandelate oxidase (decarboxylating)|(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047579 GO:0047578 biolink:MolecularActivity 4-hydroxyglutamate transaminase activity Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate. MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN|EC:2.6.1.23|Reactome:R-HSA-6784393|RHEA:10480 go-plus.json 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity|4-hydroxyglutamate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047578 GO:0106358 biolink:MolecularActivity glycerol-1-phosphate dehydrogenase [NADP+] activity Catalysis of the reaction: NADP+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADPH. RHEA:21416 go-plus.json http://purl.obolibrary.org/obo/GO_0106358 GO:0047577 biolink:MolecularActivity 4-hydroxybutyrate dehydrogenase activity Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde. MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|RHEA:23948|KEGG_REACTION:R01644|EC:1.1.1.61 go-plus.json gamma-hydroxybutyrate dehydrogenase activity|4-hydroxybutanoate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047577 GO:0047576 biolink:MolecularActivity 4-chlorobenzoate dehalogenase activity Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+). KEGG_REACTION:R01307|EC:3.8.1.6|RHEA:23440|MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN go-plus.json halobenzoate dehalogenase activity|4-chlorobenzoate chlorohydrolase activity http://purl.obolibrary.org/obo/GO_0047576 GO:0047575 biolink:MolecularActivity 4-carboxymuconolactone decarboxylase activity Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2). EC:4.1.1.44|RHEA:23348|MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN|KEGG_REACTION:R03470 go-plus.json 4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)|4-carboxymonolactone carboxy-lyase activity|gamma-4-carboxymuconolactone decarboxylase activity|4-carboxymuconolactone carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0047575 GO:0047574 biolink:MolecularActivity 4-acetamidobutyryl-CoA deacetylase activity Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate. RHEA:22928|EC:3.5.1.51|KEGG_REACTION:R04056|MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN go-plus.json deacetylase-thiolesterase activity|4-acetamidobutanoyl-CoA amidohydrolase activity|aminobutyryl-CoA thiolesterase activity http://purl.obolibrary.org/obo/GO_0047574 GO:0072539 biolink:BiologicalProcess T-helper 17 cell differentiation The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. go-plus.json T-helper 17 cell development http://purl.obolibrary.org/obo/GO_0072539 GO:0072538 biolink:BiologicalProcess T-helper 17 type immune response An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. go-plus.json Th17 immune response http://purl.obolibrary.org/obo/GO_0072538 GO:0072537 biolink:BiologicalProcess fibroblast activation A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0072537 GO:0072536 biolink:CellularComponent interleukin-23 receptor complex A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits. go-plus.json IL-23 receptor complex http://purl.obolibrary.org/obo/GO_0072536 GO:0072535 biolink:BiologicalProcess tumor necrosis factor (ligand) superfamily member 11 production The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TNFSF11 production|RANKL production|tumor necrosis factor ligand superfamily member 11 production http://purl.obolibrary.org/obo/GO_0072535 gocheck_do_not_annotate GO:0072534 biolink:CellularComponent perineuronal net A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain. go-plus.json PNN http://purl.obolibrary.org/obo/GO_0072534 GO:0106360 biolink:MolecularActivity 2-hydroxy-3-methylhexadecanoyl-CoA lyase activity Catalysis of the reaction: 2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA. RHEA:25379 go-plus.json http://purl.obolibrary.org/obo/GO_0106360 GO:0072533 biolink:MolecularActivity tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives. go-plus.json http://purl.obolibrary.org/obo/GO_0072533 GO:0072532 biolink:MolecularActivity tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives. go-plus.json http://purl.obolibrary.org/obo/GO_0072532 GO:0072531 biolink:BiologicalProcess pyrimidine-containing compound transmembrane transport The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof. go-plus.json pyrimidine-containing compound membrane transport http://purl.obolibrary.org/obo/GO_0072531 GO:0072530 biolink:BiologicalProcess purine-containing compound transmembrane transport The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof. go-plus.json purine-containing compound membrane transport http://purl.obolibrary.org/obo/GO_0072530 GO:0106364 biolink:MolecularActivity 4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]. RHEA:20361 go-plus.json http://purl.obolibrary.org/obo/GO_0106364 GO:0047584 biolink:MolecularActivity 4-oxalmesaconate hydratase activity Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O. KEGG_REACTION:R04478|EC:4.2.1.83|RHEA:17401|MetaCyc:RXN-2463 go-plus.json oxalmesaconate hydratase activity|4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity|gamma-oxalmesaconate hydratase activity|4-carboxy-2-oxohexenedioate hydratase activity|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047584 CHEBI:24610 biolink:ChemicalSubstance homocysteines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24610 GO:0047583 biolink:MolecularActivity 4-methyloxaloacetate esterase activity Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate. RHEA:10564|KEGG_REACTION:R01144|MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN|EC:3.1.1.44 go-plus.json oxaloacetate-4-methyl-ester oxaloacetohydrolase activity http://purl.obolibrary.org/obo/GO_0047583 GO:0106363 biolink:MolecularActivity protein-cysteine methyltransferase activity Catalysis of the reaction: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein]. RHEA:66544 go-plus.json http://purl.obolibrary.org/obo/GO_0106363 GO:0047582 biolink:MolecularActivity 4-methyleneglutaminase activity Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+). EC:3.5.1.67|RHEA:14741|MetaCyc:4-METHYLENEGLUTAMINASE-RXN|KEGG_REACTION:R02712 go-plus.json 4-methyleneglutamine amidohydrolase activity|4-methylene-L-glutamine amidohydrolase activity|4-methyleneglutamine deamidase activity http://purl.obolibrary.org/obo/GO_0047582 GO:0106362 biolink:MolecularActivity protein-arginine N-acetylglucosaminyltransferase activity Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP. RHEA:66632 go-plus.json http://purl.obolibrary.org/obo/GO_0106362 GO:0047581 biolink:MolecularActivity 4-methyleneglutamate-ammonia ligase activity Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+). RHEA:13853|EC:6.3.1.7|MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN|KEGG_REACTION:R02711 go-plus.json 4-methyleneglutamine synthetase activity|4-methylene-L-glutamate:ammonia ligase (AMP-forming) http://purl.obolibrary.org/obo/GO_0047581 GO:0106361 biolink:MolecularActivity protein-arginine rhamnosyltransferase activity Catalysis of the reaction: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H(+) + N(omega)-(L-rhamnosyl)-L-arginyl-[protein]. RHEA:66692 go-plus.json http://purl.obolibrary.org/obo/GO_0106361 GO:0106368 biolink:MolecularActivity dTTP dependent (deoxy)nucleoside - phosphate kinase activity Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dTTP = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP. RHEA:62132 go-plus.json http://purl.obolibrary.org/obo/GO_0106368 GO:0047580 biolink:MolecularActivity 4-hydroxyproline epimerase activity Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline. EC:5.1.1.8|RHEA:21152|KEGG_REACTION:R03296|MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN go-plus.json 4-hydroxyproline 2-epimerase activity|hydroxyproline epimerase activity|L-hydroxyproline epimerase activity|hydroxyproline 2-epimerase activity http://purl.obolibrary.org/obo/GO_0047580 GO:0106367 biolink:MolecularActivity dGTP dependent (deoxy)nucleoside -phosphate kinase activity Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP. RHEA:62128 go-plus.json http://purl.obolibrary.org/obo/GO_0106367 CHEBI:24613 biolink:ChemicalSubstance homodetic cyclic peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24613 GO:0106366 biolink:MolecularActivity guanosine kinase activity Catalysis of the reaction: ATP + guanosine = ADP + GMP. RHEA:27710|EC:2.7.1.73 go-plus.json http://purl.obolibrary.org/obo/GO_0106366 CHEBI:24612 biolink:ChemicalSubstance homocystines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24612 GO:0106365 biolink:MolecularActivity beta-carotene isomerase activity Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene. EC:5.2.1.14|RHEA:34455 go-plus.json http://purl.obolibrary.org/obo/GO_0106365 GO:0106369 biolink:MolecularActivity GTP dependent (deoxy)nucleoside -phosphate kinase activity Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP. RHEA:62124 go-plus.json http://purl.obolibrary.org/obo/GO_0106369 GO:0047589 biolink:MolecularActivity 5-aminovalerate transaminase activity Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate. EC:2.6.1.48|RHEA:10212|KEGG_REACTION:R02274|MetaCyc:VAGL-RXN go-plus.json 5-aminovalerate aminotransferase activity|delta-aminovalerate aminotransferase activity|delta-aminovalerate transaminase activity|5-aminopentanoate:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047589 GO:0047588 biolink:MolecularActivity 5-aminopentanamidase activity Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3. MetaCyc:5-AMINOPENTANAMIDASE-RXN|EC:3.5.1.30|RHEA:15677 go-plus.json 5-aminopentanamide amidohydrolase activity|5-aminovaleramidase activity|5-aminonorvaleramidase activity http://purl.obolibrary.org/obo/GO_0047588 GO:0047587 biolink:MolecularActivity 5-alpha-hydroxysteroid dehydratase activity Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O. KEGG_REACTION:R03675|EC:4.2.1.62|RHEA:22064|MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN go-plus.json 5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)|5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity|5alpha-hydroxysteroid dehydratase activity http://purl.obolibrary.org/obo/GO_0047587 GO:0047586 biolink:MolecularActivity 5'-acylphosphoadenosine hydrolase activity Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate. RHEA:16837|EC:3.6.1.20|MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN go-plus.json 5-phosphoadenosine hydrolase activity|5'-acylphosphoadenosine acylhydrolase activity http://purl.obolibrary.org/obo/GO_0047586 GO:0047585 biolink:MolecularActivity 4-pyridoxolactonase activity Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+). KEGG_REACTION:R02992|RHEA:14301|MetaCyc:4-PYRIDOXOLACTONASE-RXN|EC:3.1.1.27 go-plus.json 4-pyridoxolactone lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0047585 GO:0072529 biolink:BiologicalProcess pyrimidine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. go-plus.json pyrimidine and derivative catabolic process|pyrimidine-containing compound degradation|pyrimidine-containing compound breakdown|pyrimidine-containing compound catabolism http://purl.obolibrary.org/obo/GO_0072529 GO:0072528 biolink:BiologicalProcess pyrimidine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. go-plus.json pyrimidine-containing compound biosynthesis|pyrimidine-containing compound anabolism|pyrimidine-containing compound synthesis|pyrimidine-containing compound formation|pyrimidine and derivative biosynthetic process http://purl.obolibrary.org/obo/GO_0072528 GO:0072527 biolink:BiologicalProcess pyrimidine-containing compound metabolic process The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. go-plus.json pyrimidine-containing compound metabolism|pyrimidine and derivative metabolic process http://purl.obolibrary.org/obo/GO_0072527 GO:0072526 biolink:BiologicalProcess pyridine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. go-plus.json pyridine-containing compound catabolism|pyridine and derivative catabolic process|pyridine-containing compound degradation|pyridine-containing compound breakdown http://purl.obolibrary.org/obo/GO_0072526 GO:0072525 biolink:BiologicalProcess pyridine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. go-plus.json pyridine-containing compound anabolism|pyridine-containing compound biosynthesis|pyridine-containing compound synthesis|pyridine-containing compound formation|pyridine and derivative biosynthetic process http://purl.obolibrary.org/obo/GO_0072525 GO:0072524 biolink:BiologicalProcess pyridine-containing compound metabolic process The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. go-plus.json pyridine-containing compound metabolism|pyridine and derivative metabolic process http://purl.obolibrary.org/obo/GO_0072524 GO:0072523 biolink:BiologicalProcess purine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. go-plus.json purine and derivative catabolic process|purine-containing compound catabolism|purine-containing compound degradation|purine-containing compound breakdown http://purl.obolibrary.org/obo/GO_0072523 GO:0072522 biolink:BiologicalProcess purine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. go-plus.json purine-containing compound anabolism|purine-containing compound synthesis|purine-containing compound formation|purine and derivative biosynthetic process|purine-containing compound biosynthesis http://purl.obolibrary.org/obo/GO_0072522 GO:0106371 biolink:MolecularActivity fluorescent chlorophyll catabolite monooxygenase (deformylase) activity Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite. go-plus.json http://purl.obolibrary.org/obo/GO_0106371 GO:0072521 biolink:BiologicalProcess purine-containing compound metabolic process The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. go-plus.json purine-containing compound metabolism|purine and derivative metabolic process http://purl.obolibrary.org/obo/GO_0072521 GO:0106370 biolink:MolecularActivity protein-L-histidine N-pros-methyltransferase activity Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine. RHEA:67076 go-plus.json http://purl.obolibrary.org/obo/GO_0106370 GO:0072520 biolink:BiologicalProcess seminiferous tubule development The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. go-plus.json http://purl.obolibrary.org/obo/GO_0072520 CHEBI:24619 biolink:ChemicalSubstance homoserine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24619 GO:0106375 biolink:MolecularActivity deoxynucleoside triphosphate hydrolase activity Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate. RHEA:46148 go-plus.json http://purl.obolibrary.org/obo/GO_0106375 GO:0047595 biolink:MolecularActivity 6-hydroxynicotinate reductase activity Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin. MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN|RHEA:17225|EC:1.3.7.1 go-plus.json HNA reductase activity|6-oxotetrahydronicotinate dehydrogenase activity|6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity|1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity|6-hydroxynicotinic reductase activity|6-oxotetrahydro-nicotinate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047595 GO:0072551 biolink:MolecularActivity diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0072551 GO:0072550 biolink:MolecularActivity triferuloylspermidine meta-hydroxylase activity Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O. MetaCyc:RXN-11262 go-plus.json triferuloyl spermidine meta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0072550 GO:0047594 biolink:MolecularActivity 6-beta-hydroxyhyoscyamine epoxidase activity Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate. KEGG_REACTION:R03737|RHEA:12797|EC:1.14.20.13|MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN go-plus.json 6beta-hydroxyhyoscyamine epoxidase activity|hydroxyhyoscyamine dioxygenase activity|(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming) http://purl.obolibrary.org/obo/GO_0047594 GO:0047593 biolink:MolecularActivity 6-acetylglucose deacetylase activity Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+). MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN|KEGG_REACTION:R00327|EC:3.1.1.33|RHEA:18485 go-plus.json 6-O-acetylglucose deacetylase activity|6-acetyl-D-glucose acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0047593 GO:0106373 biolink:MolecularActivity 3-deoxyglucosone dehydrogenase activity Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD(+) = 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH. go-plus.json http://purl.obolibrary.org/obo/GO_0106373 GO:0047592 biolink:MolecularActivity 5-pyridoxate dioxygenase activity Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate) + NADP(+). EC:1.14.13.241|MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN|RHEA:11152|KEGG_REACTION:R04570 go-plus.json 5-pyridoxate oxidase activity http://purl.obolibrary.org/obo/GO_0047592 GO:0106372 biolink:MolecularActivity primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC. go-plus.json http://purl.obolibrary.org/obo/GO_0106372 GO:0106379 biolink:MolecularActivity 8-oxo-(d)RTP hydrolase activity Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+. go-plus.json http://purl.obolibrary.org/obo/GO_0106379 GO:0047591 biolink:MolecularActivity 5-hydroxypentanoate CoA-transferase activity Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate. MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN|EC:2.8.3.14|KEGG_REACTION:R04057|RHEA:23496 go-plus.json 5-hydroxyvalerate coenzyme A transferase activity|acetyl-CoA:5-hydroxypentanoate CoA-transferase activity|5-hydroxyvalerate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0047591 GO:0106378 biolink:MolecularActivity 2-hydroxy-dATP hydrolase activity Catalysis of the reaction: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate. RHEA:31583 go-plus.json http://purl.obolibrary.org/obo/GO_0106378 GO:0047590 biolink:MolecularActivity 5-dehydro-2-deoxygluconokinase activity Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate. MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN|RHEA:13497|EC:2.7.1.92 go-plus.json DKH kinase activity|5-keto-2-deoxyglucono kinase (phosphorylating)|5-keto-2-deoxygluconokinase activity|ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047590 GO:0106377 biolink:MolecularActivity 2-hydroxy-ATP hydrolase activity Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106377 GO:0106376 biolink:MolecularActivity 2-hydroxyphytanoyl-CoA lyase activity Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA. RHEA:25355 go-plus.json http://purl.obolibrary.org/obo/GO_0106376 GO:0047599 biolink:MolecularActivity 8-oxocoformycin reductase activity Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH. KEGG_REACTION:R03667|MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN|RHEA:23168|EC:1.1.1.235 go-plus.json 8-ketodeoxycoformycin reductase activity|coformycin:NADP+ 8-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047599 GO:0047598 biolink:MolecularActivity 7-dehydrocholesterol reductase activity Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+. MetaCyc:RXN66-323|Reactome:R-HSA-6807055|Reactome:R-HSA-196402|EC:1.3.1.21|RHEA:23984 go-plus.json sterol Delta(7)-reductase activity|cholesterol:NADP+ delta7-oxidoreductase activity|sterol delta7-reductase activity|7-DHC reductase activity http://purl.obolibrary.org/obo/GO_0047598 GO:0047597 biolink:MolecularActivity 6-oxocineole dehydrogenase activity Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+). EC:1.14.13.51|MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN|KEGG_REACTION:R02995|RHEA:24324 go-plus.json 6-oxocineole oxygenase activity|6-oxocineole,NADPH:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047597 GO:0047596 biolink:MolecularActivity 6-methylsalicylate decarboxylase activity Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2). KEGG_REACTION:R03567|EC:4.1.1.52|RHEA:23112|MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN go-plus.json 6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity|6-methylsalicylate carboxy-lyase activity|6-methylsalicylate carboxy-lyase (3-cresol-forming)|6-MSA decarboxylase activity http://purl.obolibrary.org/obo/GO_0047596 NCBITaxon:1338369 biolink:OrganismalEntity Dipnotetrapodomorpha go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1338369 GO:0072559 biolink:CellularComponent NLRP3 inflammasome complex An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus. go-plus.json NALP3 inflammasome complex http://purl.obolibrary.org/obo/GO_0072559 GO:0072558 biolink:CellularComponent NLRP1 inflammasome complex An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential. go-plus.json NALP1 inflammasome complex http://purl.obolibrary.org/obo/GO_0072558 GO:0072557 biolink:CellularComponent IPAF inflammasome complex An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri. go-plus.json http://purl.obolibrary.org/obo/GO_0072557 GO:0072556 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072556 GO:0072555 biolink:MolecularActivity 17-beta-ketosteroid reductase activity Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+. go-plus.json 17-beta-ketosteroid reductase (NADPH) activity|7beta-ketosteroid reductase activity http://purl.obolibrary.org/obo/GO_0072555 GO:0106381 biolink:BiologicalProcess purine deoxyribonucleotide salvage Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106381 GO:0072554 biolink:BiologicalProcess blood vessel lumenization The process in which a developing blood vessel forms an endothelial lumen through which blood will flow. go-plus.json http://purl.obolibrary.org/obo/GO_0072554 GO:0106380 biolink:BiologicalProcess purine ribonucleotide salvage Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106380 GO:0072553 biolink:BiologicalProcess terminal button organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. go-plus.json bouton organization|terminal button organisation|terminal bouton organization|presynaptic bouton organization|synaptic bouton organization http://purl.obolibrary.org/obo/GO_0072553 GO:0072552 biolink:MolecularActivity monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0072552 GO:0106386 biolink:MolecularActivity (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity Catalysis of the reaction: 3R-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH. EC:1.1.1.n12|RHEA:32711 go-plus.json http://purl.obolibrary.org/obo/GO_0106386 GO:0072540 biolink:BiologicalProcess T-helper 17 cell lineage commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. go-plus.json Th17 cell lineage commitment|Th17 fate commitment|T-helper 17 cell fate commitment http://purl.obolibrary.org/obo/GO_0072540 GO:0106385 biolink:BiologicalProcess dIMP salvage Any process which produces a dIMP from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106385 GO:0106384 biolink:BiologicalProcess dGMP salvage Any process which produces a dGMP from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106384 GO:0106383 biolink:BiologicalProcess dAMP salvage Any process which produces a dAMP from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106383 GO:0106389 biolink:MolecularActivity ecdysteroid 22-kinase activity Catalysis of the reaction: an ecdysteroid + ATP = an ecdysteroid 22-phosphate + ADP + H+. MetaCyc:RXN-14755 go-plus.json http://purl.obolibrary.org/obo/GO_0106389 GO:0106388 biolink:MolecularActivity 18S rRNA aminocarboxypropyltransferase activity Catalysis of the reaction: N1-methylpseudouridine in 18S rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in 18S rRNA + S-methyl-5'-thioadenosine. RHEA:63296 go-plus.json http://purl.obolibrary.org/obo/GO_0106388 GO:0106387 biolink:BiologicalProcess 'de novo' GMP biosynthetic process The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate. go-plus.json 'de novo' guanosine 5'-monophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0106387 GO:0072549 biolink:MolecularActivity monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0072549 GO:0072548 biolink:MolecularActivity dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0072548 GO:0072547 biolink:MolecularActivity tricoumaroylspermidine meta-hydroxylase activity Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O. MetaCyc:RXN-11260 go-plus.json tricoumaroyl spermidine meta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0072547 GO:0072546 biolink:CellularComponent EMC complex A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6. go-plus.json endoplasmic reticulum membrane protein complex|ER membrane protein complex http://purl.obolibrary.org/obo/GO_0072546 GO:0072545 biolink:MolecularActivity tyrosine binding Binding to 2-amino-3-(4-hydroxyphenyl)propanoic acid. go-plus.json Tyr binding http://purl.obolibrary.org/obo/GO_0072545 GO:0072544 biolink:MolecularActivity L-DOPA binding Binding to L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid. go-plus.json L-dopa binding http://purl.obolibrary.org/obo/GO_0072544 GO:0072543 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072543 GO:0072542 biolink:MolecularActivity protein phosphatase activator activity Binds to and increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. go-plus.json protein phosphatase type 2A activator activity|protein phosphatase type 1 activator activity|protein phosphatase 2 activator activity http://purl.obolibrary.org/obo/GO_0072542 GO:0072541 biolink:MolecularActivity peroxynitrite reductase activity Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O. go-plus.json peroxynitritase activity http://purl.obolibrary.org/obo/GO_0072541 CHEBI:73533 biolink:ChemicalSubstance N(6)-(dimethylallyl)adenosine 5'-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73533 chebi_ph7_3 CHEBI:73532 biolink:ChemicalSubstance N(6)-(dimethylallyl)adenosine 5'-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73532 chebi_ph7_3 CHEBI:48578 biolink:ChemicalSubstance radical scavenger go-plus.json http://purl.obolibrary.org/obo/CHEBI_48578 CHEBI:73534 biolink:ChemicalSubstance (9Z,12Z)-octadecadien-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73534 chebi_ph7_3 CHEBI:73537 biolink:ChemicalSubstance 1,8-naphthyridine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_73537 CHEBI:73536 biolink:ChemicalSubstance O-ureido-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73536 CHEBI:73539 biolink:ChemicalSubstance naphthyridine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_73539 PR:000010413 biolink:Protein macrophage migration inhibitory factor A protein that is a translation product of the human MIF gene or a 1:1 ortholog thereof. go-plus.json L-dopachrome tautomerase|MIF|DER6|GIF|GLIF|MMIF|phenylpyruvate tautomerase|glycosylation-inhibiting factor|delayed early response protein 6|L-dopachrome isomerase http://purl.obolibrary.org/obo/PR_000010413 PO:0020127 biolink:OntologyClass primary root A root (PO:0009005) that develops directly from a seedling radicle (PO:0020127). go-plus.json tap root (exact)|一次根 (Japanese, exact)|raíz primaria (Spanish, exact) http://purl.obolibrary.org/obo/PO_0020127 PO:0020123 biolink:OntologyClass root cap A portion of root parenchyma (PO:0025095) tissue that is part of the root tip (PO:0000025) and covers the root apical meristem (PO:0020147). go-plus.json 根冠（＝kalyptra) (Japanese, exact)|rootcap (exact)|caliptra de la raíz (Spanish, exact) http://purl.obolibrary.org/obo/PO_0020123 PO:0020121 biolink:OntologyClass lateral root A root (PO:0009005) that develops from a lateral root primordium (PO:0000016) that is part of another root on the same plant. go-plus.json raíz lateral (Spanish, exact)|側根 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020121 CHEBI:73544 biolink:ChemicalSubstance wybutosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73544 chebi_ph7_3 CHEBI:73543 biolink:ChemicalSubstance 7-[(3S)-3-amino-3-carboxypropyl]wyosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73543 chebi_ph7_3 CHEBI:73546 biolink:ChemicalSubstance grixazone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_73546 CHEBI:73548 biolink:ChemicalSubstance grixazone B go-plus.json http://purl.obolibrary.org/obo/CHEBI_73548 CHEBI:73549 biolink:ChemicalSubstance 3-hydroxy-3-(4-hydroxyphenyl)propionyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_73549 GO:0047702 biolink:MolecularActivity beta-lysine 5,6-aminomutase activity Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. KEGG_REACTION:R03275|MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN|RHEA:21736|EC:5.4.3.3 go-plus.json L-beta-lysine 5,6-aminomutase activity|beta-lysine mutase activity|b-lysine 5,6-aminomutase activity|(3S)-3,6-diaminohexanoate 5,6-aminomutase activity http://purl.obolibrary.org/obo/GO_0047702 GO:0047701 biolink:MolecularActivity beta-L-arabinosidase activity Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol. EC:3.2.1.88|MetaCyc:BETA-L-ARABINOSIDASE-RXN go-plus.json b-L-arabinosidase activity|vicianosidase activity|beta-L-arabinoside arabinohydrolase activity http://purl.obolibrary.org/obo/GO_0047701 GO:0047700 biolink:MolecularActivity beta-glucoside kinase activity Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose. MetaCyc:BETA-GLUCOSIDE-KINASE-RXN|RHEA:21944|EC:2.7.1.85 go-plus.json beta-D-glucoside kinase (phosphorylating)|ATP:cellobiose 6-phosphotransferase activity|b-glucoside kinase activity http://purl.obolibrary.org/obo/GO_0047700 CHEBI:48560 biolink:ChemicalSubstance dopaminergic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_48560 CHEBI:48561 biolink:ChemicalSubstance dopaminergic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48561 CHEBI:48563 biolink:ChemicalSubstance methylsulfanyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_48563 chebi_ph7_3 GO:0047709 biolink:MolecularActivity bis(2-ethylhexyl)phthalate esterase activity Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+). EC:3.1.1.60|KEGG_REACTION:R04202|MetaCyc:BIS2-ETHYLHEXYLPHTHALATE-ESTERASE-RXN|RHEA:15529 go-plus.json bis(2-ethylhexyl)phthalate acylhydrolase activity|DEHP esterase activity http://purl.obolibrary.org/obo/GO_0047709 GO:0047708 biolink:MolecularActivity biotinidase activity Catalysis of the reaction: biotin amide + H2O = biotin + NH3. Reactome:R-HSA-3076905|Reactome:R-HSA-3325540|RHEA:13081|Reactome:R-HSA-4167509|Reactome:R-HSA-4225086|MetaCyc:BIOTINIDASE-RXN|EC:3.5.1.12 go-plus.json biotin-amide amidohydrolase activity|amidohydrolase biotinidase activity http://purl.obolibrary.org/obo/GO_0047708 GO:0047707 biolink:MolecularActivity biotin-CoA ligase activity Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA. RHEA:19681|MetaCyc:BIOTIN--COA-LIGASE-RXN|EC:6.2.1.11 go-plus.json biotin:CoA ligase (AMP-forming)|biotinyl-CoA synthetase activity|biotinyl coenzyme A synthetase activity|biotin CoA synthetase activity http://purl.obolibrary.org/obo/GO_0047707 GO:0047706 biolink:MolecularActivity biochanin-A reductase activity Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH. RHEA:12817|EC:1.3.1.46|KEGG_REACTION:R02954|MetaCyc:BIOCHANIN-A-REDUCTASE-RXN go-plus.json dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047706 GO:0047705 biolink:MolecularActivity bilirubin oxidase activity Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O. KEGG_REACTION:R02394|EC:1.3.3.5|MetaCyc:BILIRUBIN-OXIDASE-RXN|RHEA:20980 go-plus.json bilirubin oxidase M-1|bilirubin:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047705 GO:0047704 biolink:MolecularActivity bile-salt sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate. RHEA:14013|EC:2.8.2.14|MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN go-plus.json bile acid sulfotransferase I activity|glycolithocholate sulfotransferase activity|bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity|bile-salt sulphotransferase activity|BAST I activity|3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047704 goslim_chembl GO:0047703 biolink:MolecularActivity beta-nitroacrylate reductase activity Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH. RHEA:23892|MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN|EC:1.3.1.16|KEGG_REACTION:R03900 go-plus.json b-nitroacrylate reductase activity|3-nitropropanoate:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047703 CHEBI:73542 biolink:ChemicalSubstance N(1)-methylguanosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73542 chebi_ph7_3 CHEBI:73541 biolink:ChemicalSubstance organic heterobicyclic ring go-plus.json http://purl.obolibrary.org/obo/CHEBI_73541 CHEBI:73555 biolink:ChemicalSubstance 7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73555 chebi_ph7_3 CHEBI:24588 biolink:ChemicalSubstance hexose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24588 CHEBI:24587 biolink:ChemicalSubstance hexosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24587 CHEBI:73557 biolink:ChemicalSubstance 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73557 CHEBI:24586 biolink:ChemicalSubstance hexosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24586 CHEBI:73556 biolink:ChemicalSubstance 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73556 CHEBI:24585 biolink:ChemicalSubstance hexosamine sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24585 CHEBI:73559 biolink:ChemicalSubstance 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73559 CHEBI:73558 biolink:ChemicalSubstance D3 vitamins go-plus.json http://purl.obolibrary.org/obo/CHEBI_73558 CHEBI:24589 biolink:ChemicalSubstance monosaccharide sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24589 GO:0047713 biolink:MolecularActivity galactitol 2-dehydrogenase activity Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH. RHEA:20685|MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.16|KEGG_REACTION:R02928 go-plus.json http://purl.obolibrary.org/obo/GO_0047713 CHEBI:24580 biolink:ChemicalSubstance hexenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24580 GO:0047712 biolink:MolecularActivity Cypridina-luciferin 2-monooxygenase activity Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light. MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:22760|EC:1.13.12.6 go-plus.json Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Cypridina-type luciferase activity|luciferase activity|luciferase (Cypridina luciferin)|Cypridina luciferase activity http://purl.obolibrary.org/obo/GO_0047712 GO:0047711 biolink:MolecularActivity blasticidin-S deaminase activity Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3. MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN|RHEA:10148|EC:3.5.4.23 go-plus.json blasticidin-S aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047711 GO:0047710 biolink:MolecularActivity bis(5'-adenosyl)-triphosphatase activity Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+). MetaCyc:BIS5-ADENOSYL-TRIPHOSPHATASE-RXN|EC:3.6.1.29|KEGG_REACTION:R00187|RHEA:13893 go-plus.json AP3A hydrolase activity|AP3Aase activity|dinucleosidetriphosphatase activity|1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity|diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity|AP(3)Aase activity|diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity|diadenosine 5,5-P1,P3-triphosphatase activity|AP(3)A hydrolase activity|P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity http://purl.obolibrary.org/obo/GO_0047710 CHEBI:48551 biolink:ChemicalSubstance guanidino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_48551 CHEBI:24584 biolink:ChemicalSubstance hexosamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24584 CHEBI:48550 biolink:ChemicalSubstance EC 1.1.1.21 (aldehyde reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_48550 CHEBI:24583 biolink:ChemicalSubstance hexitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24583 CHEBI:24582 biolink:ChemicalSubstance hexitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24582 GO:0047719 biolink:MolecularActivity indole 2,3-dioxygenase activity Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde. KEGG_REACTION:R02338|MetaCyc:INDOLE-23-DIOXYGENASE-RXN|RHEA:11212|EC:1.13.11.17 go-plus.json indole-oxygen 2,3-oxidoreductase (decyclizing)|indole oxidase activity|indole:oxygen 2,3-oxidoreductase (decyclizing)|IDO|indole:O2 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047719 GO:0047718 biolink:MolecularActivity indanol dehydrogenase activity Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+. MetaCyc:INDANOL-DEHYDROGENASE-RXN|EC:1.1.1.112 go-plus.json indan-1-ol:NAD(P)+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047718 GO:0047717 biolink:MolecularActivity imidazoleacetate 4-monooxygenase activity Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+). MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN|RHEA:19425|KEGG_REACTION:R04066|EC:1.14.13.5 go-plus.json 4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)|imidazoleacetate hydroxylase activity|imidazoleacetic monooxygenase activity|imidazoleacetic hydroxylase activity http://purl.obolibrary.org/obo/GO_0047717 GO:0047716 biolink:MolecularActivity imidazole N-acetyltransferase activity Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA. MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN|RHEA:15813|KEGG_REACTION:R03621|EC:2.3.1.2 go-plus.json acetyl-CoA:imidazole N-acetyltransferase activity|imidazole acetyltransferase activity|imidazole acetylase activity http://purl.obolibrary.org/obo/GO_0047716 PO:0020108 biolink:OntologyClass suspensor An embryonic plant structure at the base of a plant embryo that develops from an embryonic basal cell and connects an embryo proper to the wall of a megagametophyte. go-plus.json suspensor (Spanish, exact)|胚柄 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020108 GO:0047715 biolink:MolecularActivity hypotaurocyamine kinase activity Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+). KEGG_REACTION:R03939|MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN|RHEA:24008|EC:2.7.3.6 go-plus.json ATP:hypotaurocyamine N-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047715 GO:0047714 biolink:MolecularActivity galactolipase activity Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates. EC:3.1.1.26|RHEA:13189|MetaCyc:GALACTOLIPASE-RXN go-plus.json galactolipid lipase activity|galactolipid acylhydrolase activity|polygalactolipase activity|1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity http://purl.obolibrary.org/obo/GO_0047714 PO:0020102 biolink:OntologyClass portion of transmitting tissue A portion of ground tissue (PO:0025059) in the style of a carpel through which a pollen tube grows; it connects a stigma and the inside of an ovary. go-plus.json transmitting tract (related)|porción del tejido de transmisión (Spanish, exact)|伝達組織の一部 (Japanese, exact)|Poaceae transmitting tissue (narrow) http://purl.obolibrary.org/obo/PO_0020102 PO:0020101 biolink:OntologyClass stomium A plant anatomical space that is a slit in an anther lobe formed from when a dehiscence zone dehisces. go-plus.json Zea stomium (narrow)|stomia (exact, plural)|Poaceae stomium (narrow)|estomio (Spanish, exact)|口辺細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020101 CHEBI:73550 biolink:ChemicalSubstance 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73550 chebi_ph7_3 CHEBI:73553 biolink:ChemicalSubstance 7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73553 CHEBI:73552 biolink:ChemicalSubstance 7-[(3S-amino)-3-carboxypropyl]wyosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73552 CHEBI:48544 biolink:ChemicalSubstance methanesulfonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_48544 CHEBI:24599 biolink:ChemicalSubstance histidine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24599 CHEBI:48545 biolink:ChemicalSubstance pentapeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48545 GO:0047724 biolink:MolecularActivity inosine nucleosidase activity Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine. EC:3.2.2.2|MetaCyc:INOSINE-NUCLEOSIDASE-RXN|RHEA:16657 go-plus.json inosine-guanosine nucleosidase activity|inosinase activity|inosine ribohydrolase activity http://purl.obolibrary.org/obo/GO_0047724 CHEBI:24591 biolink:ChemicalSubstance hexuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24591 GO:0047723 biolink:MolecularActivity inosinate nucleosidase activity Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine. MetaCyc:INOSINATE-NUCLEOSIDASE-RXN|RHEA:20469|KEGG_REACTION:R01128|EC:3.2.2.12 go-plus.json 5'-inosinate phosphoribohydrolase activity http://purl.obolibrary.org/obo/GO_0047723 GO:0047722 biolink:MolecularActivity indolelactate dehydrogenase (NADH) activity Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH. EC:1.1.1.110|MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01971|RHEA:20133 go-plus.json indolelactate:NAD+ oxidoreductase activity|(indol-3-yl)lactate:NAD+ oxidoreductase activity|indole-3-lactate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047722 GO:0047721 biolink:MolecularActivity indoleacetate-lysine synthetase activity Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate. KEGG_REACTION:R03095|MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN|RHEA:14857|EC:6.3.2.20 go-plus.json indoleacetate:L-lysine ligase (ADP-forming)|N-(indole-3-acetyl)-L-lysine synthetase activity|indoleacetate-lysine ligase activity|IAA-lysine synthetase activity|(indol-3-yl)acetate:L-lysine ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0047721 GO:0047720 biolink:MolecularActivity indoleacetaldoxime dehydratase activity Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O. EC:4.99.1.6|KEGG_REACTION:R04093|MetaCyc:RXN-1403|RHEA:23156 go-plus.json indole-3-acetaldoxime hydro-lyase activity|3-indoleacetaldoxime hydro-lyase activity|indole-3-acetaldehyde-oxime hydro-lyase activity|indoleacetaldoxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming] http://purl.obolibrary.org/obo/GO_0047720 CHEBI:48540 biolink:ChemicalSubstance beta-adrenergic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48540 CHEBI:48542 biolink:ChemicalSubstance deca-2,4,6,8-tetraenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48542 CHEBI:24592 biolink:ChemicalSubstance hexuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24592 GO:0047729 biolink:MolecularActivity carnitine decarboxylase activity Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2). MetaCyc:CARNITINE-DECARBOXYLASE-RXN|EC:4.1.1.42|RHEA:21576|KEGG_REACTION:R02398 go-plus.json carnitine carboxy-lyase activity|carnitine carboxy-lyase (2-methylcholine-forming) http://purl.obolibrary.org/obo/GO_0047729 GO:0047728 biolink:MolecularActivity carnitine 3-dehydrogenase activity Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH. EC:1.1.1.108|RHEA:19265|MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN|KEGG_REACTION:R02395 go-plus.json carnitine:NAD+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047728 GO:0047727 biolink:MolecularActivity isobutyryl-CoA mutase activity Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA. RHEA:13141|KEGG_REACTION:R01181|EC:5.4.99.13|MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN go-plus.json 2-methylpropanoyl-CoA CoA-carbonylmutase activity|isobutyryl coenzyme A mutase activity|butyryl-CoA:isobutyryl-CoA mutase activity http://purl.obolibrary.org/obo/GO_0047727 GO:0047726 biolink:MolecularActivity iron-cytochrome-c reductase activity Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+. EC:1.9.98.1|RHEA:15617|MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN go-plus.json iron-cytochrome c reductase activity|ferrocytochrome-c:Fe3+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047726 GO:0047725 biolink:MolecularActivity inulosucrase activity Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1). MetaCyc:INULOSUCRASE-RXN|RHEA:15745|EC:2.4.1.9 go-plus.json sucrose 1-fructosyl transferase activity|sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|sucrose 1-fructosyltransferase activity http://purl.obolibrary.org/obo/GO_0047725 CHEBI:48536 biolink:ChemicalSubstance amidopyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48536 CHEBI:48539 biolink:ChemicalSubstance alpha-adrenergic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48539 CHEBI:24567 biolink:ChemicalSubstance cyclohexane-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24567 chebi_ph7_3 GO:0047735 biolink:MolecularActivity cellobiose dehydrogenase (acceptor) activity Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor. MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:23484|EC:1.1.99.18 go-plus.json cellobiose dehydrogenase (quinone) activity|cellobiose-quinone oxidoreductase activity|cellobiose:(acceptor) 1-oxidoreductase activity|phanerochaete chrysosporium cellobiose oxidoreductase activity|cellobiose:acceptor 1-oxidoreductase activity|cellobiose oxidase activity|cellobiose dehydrogenase activity|cellobiose:oxygen 1-oxidoreductase activity|CBOR activity|cellobiose oxidoreductase activity|CDH activity http://purl.obolibrary.org/obo/GO_0047735 GO:0047734 biolink:MolecularActivity CDP-glycerol diphosphatase activity Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+). KEGG_REACTION:R00855|EC:3.6.1.16|RHEA:21692|MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN go-plus.json CDP-glycerol pyrophosphatase activity|cytidine diphosphoglycerol pyrophosphatase activity|CDPglycerol phosphoglycerohydrolase activity|CDPglycerol pyrophosphatase activity|CDPglycerol diphosphatase activity|CDP-glycerol phosphoglycerohydrolase activity http://purl.obolibrary.org/obo/GO_0047734 GO:0047733 biolink:MolecularActivity CDP-glucose 4,6-dehydratase activity Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O. EC:4.2.1.45|KEGG_REACTION:R02426|RHEA:17153|MetaCyc:CDP-GLUCOSE-46-DEHYDRATASE-RXN go-plus.json CDPglucose 4,6-hydro-lyase activity|CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)|cytidine diphosphoglucose oxidoreductase activity|CDP-glucose 4,6-hydro-lyase activity|CDPglucose 4,6-dehydratase activity http://purl.obolibrary.org/obo/GO_0047733 UBERON:0015757 biolink:AnatomicalEntity heterogeneous tissue go-plus.json portion of heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0015757 GO:0047732 biolink:MolecularActivity CDP-abequose epimerase activity Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose. RHEA:21656|EC:5.1.3.10|MetaCyc:RXN-9160|KEGG_REACTION:R04266 go-plus.json cytidine diphosphoparatose epimerase activity|CDP-paratose epimerase activity|CDP-tyvelose 2-epimerase activity|CDP-paratose 2-epimerase activity|cytidine diphosphoabequose epimerase activity|CDP-3,6-dideoxy-D-glucose 2-epimerase activity|cytidine diphosphodideoxyglucose epimerase activity|cytidine diphosphate paratose-2-epimerase activity|CDP-D-abequose 2-epimerase activity http://purl.obolibrary.org/obo/GO_0047732 GO:0047731 biolink:MolecularActivity catechol oxidase (dimerizing) activity Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O. MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN|RHEA:12809|EC:1.1.3.14 go-plus.json catechol:oxygen oxidoreductase (dimerizing) http://purl.obolibrary.org/obo/GO_0047731 GO:0047730 biolink:MolecularActivity carnosine synthase activity Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine. MetaCyc:CARNOSINE-SYNTHASE-RXN|EC:6.3.2.11|RHEA:19297|Reactome:R-HSA-6786245 go-plus.json carnosine synthetase activity|L-histidine:beta-alanine ligase (AMP-forming)|carnosine-anserine synthetase activity|carnosine-homocarnosine synthetase activity|homocarnosine-carnosine synthetase activity http://purl.obolibrary.org/obo/GO_0047730 CHEBI:24561 biolink:ChemicalSubstance hexahydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24561 GO:0047739 biolink:MolecularActivity cephalosporin-C deacetylase activity Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+). MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN|EC:3.1.1.41|RHEA:22596|KEGG_REACTION:R03062 go-plus.json cephalosporin-C acetylhydrolase activity|cephalosporin C acetyl-esterase activity|cephalosporin C acetyl-hydrolase activity|cephalosporin C deacetylase activity|cephalosporin C acetylase activity|cephalosporin C acetylesterase activity|cephalosporin acetylesterase activity http://purl.obolibrary.org/obo/GO_0047739 GO:0047738 biolink:MolecularActivity cellobiose phosphorylase activity Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose. EC:2.4.1.20|RHEA:19493|MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN go-plus.json cellobiose:phosphate alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047738 GO:0047737 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047737 GO:0047736 biolink:MolecularActivity cellobiose epimerase activity Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose. EC:5.1.3.11|RHEA:23384|MetaCyc:CELLOBIOSE-EPIMERASE-RXN go-plus.json cellobiose 2-epimerase activity http://purl.obolibrary.org/obo/GO_0047736 UBERON:0001114 biolink:AnatomicalEntity right lobe of liver The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]. go-plus.json right hepatic lobe|liver right lobe|right liver lobe|gall bladder lobe|2nd lobe|lobus hepatis dexter|lobus hepaticus dexter|second lobe http://purl.obolibrary.org/obo/UBERON_0001114 UBERON:0001113 biolink:AnatomicalEntity lobe of liver Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe. go-plus.json hepatic lobe|liver lobe|lobus hepatis http://purl.obolibrary.org/obo/UBERON_0001113 UBERON:0001115 biolink:AnatomicalEntity left lobe of liver The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]. go-plus.json liver left lobe|lobus hepaticus sinister|left hepatic lobe|left liver lobe|lobus hepatis sinister http://purl.obolibrary.org/obo/UBERON_0001115 UBERON:0001112 biolink:AnatomicalEntity latissimus dorsi muscle The latissimus dorsi is the larger, flat, dorso-lateral muscle on the trunk, posterior to the arm, and partly covered by the trapezius on its median dorsal region. [WP,unvetted]. go-plus.json dorsal latissimus muscle|musculus latissimus dorsi|latissimi dorsi|musculus latissimus dorsi|latissimus dorsi http://purl.obolibrary.org/obo/UBERON_0001112 CHEBI:24577 biolink:ChemicalSubstance hexaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24577 CHEBI:24576 biolink:ChemicalSubstance hexaric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_24576 CHEBI:48526 biolink:ChemicalSubstance hydratropic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48526 CHEBI:48527 biolink:ChemicalSubstance (S)-hydratropic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48527 CHEBI:24578 biolink:ChemicalSubstance hexenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_24578 GO:0047746 biolink:MolecularActivity chlorophyllase activity Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide. EC:3.1.1.14|MetaCyc:CHLOROPHYLLASE-RXN go-plus.json chlorophyll chlorophyllidohydrolase activity http://purl.obolibrary.org/obo/GO_0047746 GO:0047745 biolink:MolecularActivity chlorogenate hydrolase activity Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+). MetaCyc:CHLOROGENATE-HYDROLASE-RXN|RHEA:20689|EC:3.1.1.42|KEGG_REACTION:R02997 go-plus.json chlorogenic acid esterase activity|chlorogenase activity http://purl.obolibrary.org/obo/GO_0047745 GO:0047744 biolink:MolecularActivity chloridazon-catechol dioxygenase activity Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+). EC:1.13.11.36|RHEA:20449|MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN|KEGG_REACTION:R04602 go-plus.json 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0047744 GO:0047743 biolink:MolecularActivity chlordecone reductase activity Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH. KEGG_REACTION:R03716|RHEA:14401|MetaCyc:CHLORDECONE-REDUCTASE-RXN|EC:1.1.1.225 go-plus.json chlordecone-alcohol:NADP+ 2-oxidoreductase activity|CDR activity http://purl.obolibrary.org/obo/GO_0047743 GO:0047742 biolink:MolecularActivity chenodeoxycholoyltaurine hydrolase activity Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine. MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN|RHEA:16309|EC:3.5.1.74 go-plus.json chenodeoxycholoyltaurine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047742 CHEBI:24573 biolink:ChemicalSubstance hexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24573 GO:0047741 biolink:MolecularActivity cetraxate benzylesterase activity Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+). KEGG_REACTION:R03612|EC:3.1.1.70|RHEA:23460|MetaCyc:CETRAXATE-BENZYLESTERASE-RXN go-plus.json cetraxate-benzyl-ester benzylhydrolase activity http://purl.obolibrary.org/obo/GO_0047741 GO:0047740 biolink:MolecularActivity cephalosporin-C transaminase activity Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C. MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN|EC:2.6.1.74|RHEA:14553|KEGG_REACTION:R03063 go-plus.json L-alanine:cephalosporin-C aminotransferase activity|cephalosporin C aminotransferase activity|cephalosporin-C:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047740 CHEBI:167609 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_167609 CHEBI:167605 biolink:ChemicalSubstance 1,8-dihydroxynaphthalene-melanin go-plus.json http://purl.obolibrary.org/obo/CHEBI_167605 GO:0047749 biolink:MolecularActivity cholestanetriol 26-monooxygenase activity Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O. EC:1.14.15.15|MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN|RHEA:14373 go-plus.json cytochrome P450 27A1' activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity|cholesterol 27-hydroxylase activity|CYP27A|sterol 27-hydroxylase activity|sterol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)|CYP27A1|cholestanetriol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity http://purl.obolibrary.org/obo/GO_0047749 CHEBI:167604 biolink:ChemicalSubstance naphthalene-1,8-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_167604 GO:0047748 biolink:MolecularActivity cholestanetetraol 26-dehydrogenase activity Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH. RHEA:34631|MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN go-plus.json 5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity|TEHC-NAD oxidoreductase activity|5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity|cholestanetetrol 26-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047748 GO:0047747 biolink:MolecularActivity cholate-CoA ligase activity Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA. MetaCyc:CHOLATE--COA-LIGASE-RXN|EC:6.2.1.7 go-plus.json 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|trihydroxycoprostanoyl-CoA synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity|cholyl-CoA synthetase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity|cholate thiokinase activity|BAL activity|cholic acid:CoA ligase activity|THCA-CoA ligase activity|cholate:CoA ligase (AMP-forming)|bile acid CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity|bile acid coenzyme A ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity|choloyl coenzyme A synthetase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity|choloyl-CoA synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)|cholic thiokinase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity http://purl.obolibrary.org/obo/GO_0047747 UBERON:0001103 biolink:AnatomicalEntity diaphragm A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control go-plus.json diaphragm muscle|diaphragm of thorax|phren|thoracic diaphragm|midriff http://purl.obolibrary.org/obo/UBERON_0001103 CHEBI:48529 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_48529 chebi_ph7_3 UBERON:0001105 biolink:AnatomicalEntity clavicle bone A paired dermal or endochondral bone that is part of the pectoral girdle. The clavicle may be in contact with the interclavicle or coracoid and forms an attachment site for pectoral musculature. [PHENOSCAPE:ad]. go-plus.json clavicula|clavicle|collar bone|collarbone http://purl.obolibrary.org/obo/UBERON_0001105 CHEBI:73599 biolink:ChemicalSubstance 3-methylthioaspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73599 chebi_ph7_3 CHEBI:48513 biolink:ChemicalSubstance carbazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_48513 CHEBI:24548 biolink:ChemicalSubstance hexadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24548 CHEBI:24547 biolink:ChemicalSubstance hexadecenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_24547 CHEBI:48517 biolink:ChemicalSubstance 7H-xanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48517 chebi_ph7_3 CHEBI:24546 biolink:ChemicalSubstance hexadecen-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24546 CHEBI:24545 biolink:ChemicalSubstance hexadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24545 GO:0047757 biolink:MolecularActivity chondroitin-glucuronate 5-epimerase activity Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate. RHEA:21084|Reactome:R-HSA-2022052|MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN|EC:5.1.3.19 go-plus.json polyglucuronate 5-epimerase activity|chondroitin-D-glucuronate 5-epimerase activity|chondroitin D-glucuronosyl 5-epimerase activity|dermatan-sulfate 5-epimerase activity|urunosyl C-5 epimerase activity http://purl.obolibrary.org/obo/GO_0047757 CHEBI:167612 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide)(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_167612 GO:0047756 biolink:MolecularActivity chondroitin 4-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate. EC:2.8.2.5|RHEA:16101|MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN|Reactome:R-HSA-1971483 go-plus.json chondroitin 4-sulphotransferase activity|3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047756 GO:0047755 biolink:MolecularActivity isocitrate epimerase activity Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate. RHEA:10820|EC:5.1.2.6|MetaCyc:ISOCITRATE-EPIMERASE-RXN|KEGG_REACTION:R02318 go-plus.json (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity http://purl.obolibrary.org/obo/GO_0047755 CHEBI:167614 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide)(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_167614 GO:0047754 biolink:MolecularActivity choline sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+). RHEA:21984|KEGG_REACTION:R01027|EC:2.8.2.6|MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN go-plus.json choline sulphokinase activity|3'-phosphoadenylyl-sulfate:choline sulfotransferase activity|choline sulphotransferase activity http://purl.obolibrary.org/obo/GO_0047754 GO:0047753 biolink:MolecularActivity choline-sulfatase activity Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate. EC:3.1.6.6|MetaCyc:CHOLINE-SULFATASE-RXN|RHEA:20820|KEGG_REACTION:R01028 go-plus.json choline-sulphatase activity|choline-sulfate sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0047753 GO:0047752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047752 GO:0047751 biolink:MolecularActivity cholestenone 5-alpha-reductase activity Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH. KEGG_REACTION:R02610|RHEA:24552|EC:1.3.1.22|MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN go-plus.json reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity|cholestenone 5a-reductase activity|4-ene-3-oxosteroid 5alpha-reductase activity|cholestenone 5alpha-reductase activity|3-oxosteroid delta4-dehydrogenase|4-ene-5alpha-reductase activity|testosterone delta4-5alpha-reductase activity|testosterone delta4-hydrogenase activity|3-oxosteroid 5alpha-reductase activity|3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity|cholest-4-en-3-one 5alpha-reductase activity|delta4-3-ketosteroid 5alpha-oxidoreductase activity|steroid 5alpha-hydrogenase activity|testosterone 5alpha-reductase|steroid 5alpha-reductase|5alpha-reductase http://purl.obolibrary.org/obo/GO_0047751 GO:0047750 biolink:MolecularActivity cholestenol delta-isomerase activity Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol. EC:5.3.3.5|RHEA:15281|MetaCyc:RXN66-25 go-plus.json delta7-cholestenol delta7-delta8-isomerase activity|cholestenol D-isomerase activity http://purl.obolibrary.org/obo/GO_0047750 GO:0072719 biolink:BiologicalProcess cellular response to cisplatin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072719 GO:0072718 biolink:BiologicalProcess response to cisplatin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072718 GO:0072717 biolink:BiologicalProcess cellular response to actinomycin D Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072717 CHEBI:167616 biolink:ChemicalSubstance 5'-end ribonucleoside 5'-diphosphate(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_167616 PO:0020149 biolink:OntologyClass quiescent center A portion of meristem tissue (PO:0009013) that is part of a root apical meristem (PO:0020147) and consists of mitotically and metabolically inactive cells and is located behind the protoderm (PO:0006210) of the root (PO:0009005). go-plus.json centro de division de células del meristema (Spanish, exact)|静止中心 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020149 GO:0072716 biolink:BiologicalProcess response to actinomycin D Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072716 GO:0072715 biolink:BiologicalProcess cellular response to selenite ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072715 GO:0047759 biolink:MolecularActivity butanal dehydrogenase activity Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+. MetaCyc:BUTANAL-DEHYDROGENASE-RXN|EC:1.2.1.57 go-plus.json butanal:NAD(P)+ oxidoreductase (CoA-acylating) http://purl.obolibrary.org/obo/GO_0047759 CHEBI:167618 biolink:ChemicalSubstance 5'-end ribonucleotide 5'-triphosphate(4-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_167618 GO:0047758 biolink:MolecularActivity ATP:2-methylpropanoate phosphotransferase activity Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+). EC:2.7.2.14|RHEA:24156|KEGG_REACTION:R04002|MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN go-plus.json ATP:2-methylpropanoate 1-phosphotransferase activity|branched-chain fatty acid kinase activity|branched-chain-fatty-acid kinase activity|ATP:isobutyrate 1-phosphotransferase activity|ATP:branched-chain-fatty-acid 1-phosphotransferase activity|isobutyrate kinase activity|ATP:2-methylpropanoate kinase activity http://purl.obolibrary.org/obo/GO_0047758 GO:0072714 biolink:BiologicalProcess response to selenite ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072714 CHEBI:167617 biolink:ChemicalSubstance 5'-(5'-triphosphoguanosine)-(ribonucleotide)(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_167617 GO:0072713 biolink:BiologicalProcess cellular response to thiabendazole Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus. go-plus.json cellular response to TBZ http://purl.obolibrary.org/obo/GO_0072713 GO:0072712 biolink:BiologicalProcess response to thiabendazole Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus. go-plus.json response to TBZ http://purl.obolibrary.org/obo/GO_0072712 PO:0020148 biolink:OntologyClass shoot apical meristem A shoot system meristem (PO:0006079) formed at the apex of the shoot axis (PO:0025029), including those originating from an axillary bud meristem (PO:0000232). go-plus.json SAM (exact)|meristema apical del epiblasto (epiblastema) (Spanish, exact)|promeristem (broad)|primary shoot meristem (related)|茎頂分裂組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020148 GO:0072711 biolink:BiologicalProcess cellular response to hydroxyurea Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus. go-plus.json cellular response to HU http://purl.obolibrary.org/obo/GO_0072711 PO:0020147 biolink:OntologyClass root apical meristem A root meristem (PO:0006085) located at the root tip (PO:0000025), behind the root cap (PO:0020123). go-plus.json RAM (exact)|promeristem (broad)|meristema apical de la raíz (Spanish, exact)|根端分裂組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020147 GO:0072710 biolink:BiologicalProcess response to hydroxyurea Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus. go-plus.json response to HU http://purl.obolibrary.org/obo/GO_0072710 CHEBI:24549 biolink:ChemicalSubstance hexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_24549 PO:0020144 biolink:OntologyClass apical meristem A maximal portion of meristem tissue (PO:0009013) located at a shoot apex (PO:0000037) or root tip (PO:0000025). go-plus.json 頂端分裂組織 (Japanese, exact)|promeristem (broad)|meristema apical (Spanish, exact)|AM (exact)|primary meristem (related) http://purl.obolibrary.org/obo/PO_0020144 GO:0047760 biolink:MolecularActivity butyrate-CoA ligase activity Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA. Reactome:R-HSA-8875013|RHEA:24336|MetaCyc:BUTYRATE--COA-LIGASE-RXN|EC:6.2.1.2 go-plus.json butyryl-coenzyme A synthetase activity|short-chain acyl-CoA synthetase activity|fatty acid activating enzyme|medium chain acyl-CoA synthetase activity|fatty acid thiokinase (medium chain) activity|fatty acyl coenzyme A synthetase activity|butyryl-CoA synthetase activity|butanoate:CoA ligase (AMP-forming)|L-(+)-3-hydroxybutyryl CoA ligase activity|acyl-activating enzyme activity http://purl.obolibrary.org/obo/GO_0047760 CHEBI:24555 biolink:ChemicalSubstance hexadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24555 CHEBI:24554 biolink:ChemicalSubstance hexadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24554 CHEBI:24553 biolink:ChemicalSubstance hexadienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24553 CHEBI:24552 biolink:ChemicalSubstance hexadienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24552 GO:0047768 biolink:MolecularActivity carboxy-cis,cis-muconate cyclase activity Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate. KEGG_REACTION:R03308|RHEA:14977|EC:5.5.1.5|MetaCyc:CARBOXY-CISCIS-MUCONATE-CYCLASE-RXN go-plus.json 3-carboxymuconate cyclase activity|3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)|3-carboxy-cis,cis-muconate lactonizing enzyme activity http://purl.obolibrary.org/obo/GO_0047768 GO:0047767 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047767 GO:0047766 biolink:MolecularActivity carbamoyl-serine ammonia-lyase activity Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate. MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN|EC:4.3.1.13|KEGG_REACTION:R00213|RHEA:15445 go-plus.json O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)|O-carbamoyl-L-serine deaminase activity|carbamoylserine deaminase activity|O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming) http://purl.obolibrary.org/obo/GO_0047766 GO:0047765 biolink:MolecularActivity caldesmon-phosphatase activity Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate. MetaCyc:CALDESMON-PHOSPHATASE-RXN|EC:3.1.3.55 go-plus.json smooth muscle caldesmon phosphatase activity|SMP-I|caldesmon-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047765 CHEBI:24551 biolink:ChemicalSubstance hexadienal go-plus.json http://purl.obolibrary.org/obo/CHEBI_24551 GO:0047764 biolink:MolecularActivity obsolete caldesmon kinase activity OBSOLETE. Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate. MetaCyc:2.7.11.17-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0047764 GO:0047763 biolink:MolecularActivity caffeate O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate. MetaCyc:RXN-1104|EC:2.1.1.68|RHEA:20225 go-plus.json caffeate methyltransferase activity|S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity|caffeate 3-O-methyltransferase activity|S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0047763 GO:0047762 biolink:MolecularActivity caffeate 3,4-dioxygenase activity Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+). EC:1.13.11.22|RHEA:22216|MetaCyc:CAFFEATE-34-DIOXYGENASE-RXN|KEGG_REACTION:R03365 go-plus.json 3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0047762 GO:0047761 biolink:MolecularActivity butyrate kinase activity Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+). KEGG_REACTION:R01688|EC:2.7.2.7|RHEA:13585|MetaCyc:BUTYRATE-KINASE-RXN go-plus.json ATP:butanoate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047761 GO:0072709 biolink:BiologicalProcess cellular response to sorbitol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus. go-plus.json cellular response to glucitol http://purl.obolibrary.org/obo/GO_0072709 GO:0072708 biolink:BiologicalProcess response to sorbitol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus. go-plus.json response to glucitol http://purl.obolibrary.org/obo/GO_0072708 GO:0072707 biolink:BiologicalProcess cellular response to sodium dodecyl sulfate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus. go-plus.json cellular response to SDS http://purl.obolibrary.org/obo/GO_0072707 GO:0072706 biolink:BiologicalProcess response to sodium dodecyl sulfate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus. go-plus.json response to SDS http://purl.obolibrary.org/obo/GO_0072706 GO:0072705 biolink:BiologicalProcess cellular response to mercaptoethanol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus. go-plus.json cellular response to 2-sulfanylethanol http://purl.obolibrary.org/obo/GO_0072705 GO:0072704 biolink:BiologicalProcess response to mercaptoethanol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus. go-plus.json response to 2-sulfanylethanol http://purl.obolibrary.org/obo/GO_0072704 UBERON:0015717 biolink:AnatomicalEntity smooth muscle tissue layer of ejaculatory duct A smooth muscle tissue that is part of a ejaculatory duct. go-plus.json muscle layer of ejaculatory duct http://purl.obolibrary.org/obo/UBERON_0015717 GO:0072703 biolink:BiologicalProcess cellular response to methyl methanesulfonate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus. go-plus.json cellular response to MMS http://purl.obolibrary.org/obo/GO_0072703 GO:0047769 biolink:MolecularActivity arogenate dehydratase activity Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2. MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN|RHEA:12536|EC:4.2.1.91 go-plus.json L-arogenate hydro-lyase (decarboxylating)|carboxycyclohexadienyl dehydratase activity|L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming) http://purl.obolibrary.org/obo/GO_0047769 PR:000010444 biolink:Protein mitogen-activated protein kinase kinase kinase 21 A protein that is a translation product of the human MAP3K21 gene or a 1:1 ortholog thereof. go-plus.json MAP3K21|mixed lineage kinase 4|MLK4|mitogen-activated protein kinase kinase kinase MLK4 http://purl.obolibrary.org/obo/PR_000010444 UBERON:0015716 biolink:AnatomicalEntity anal canal epithelium A epithelium that is part of a anal canal. go-plus.json anal canal epithelium|epithelium of anal canal http://purl.obolibrary.org/obo/UBERON_0015716 GO:0072702 biolink:BiologicalProcess response to methyl methanesulfonate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus. go-plus.json response to MMS http://purl.obolibrary.org/obo/GO_0072702 GO:0072701 biolink:BiologicalProcess cellular response to bismuth Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus. go-plus.json cellular response to bismuth ion http://purl.obolibrary.org/obo/GO_0072701 GO:0072700 biolink:BiologicalProcess response to bismuth Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus. go-plus.json response to bismuth ion http://purl.obolibrary.org/obo/GO_0072700 GO:0033129 biolink:BiologicalProcess positive regulation of histone phosphorylation Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0033129 GO:0033128 biolink:BiologicalProcess negative regulation of histone phosphorylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0033128 GO:0008169 biolink:MolecularActivity C-methyltransferase activity Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule. EC:2.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0008169 GO:0008168 biolink:MolecularActivity methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule. EC:2.1.1.-|Reactome:R-HSA-379387|Reactome:R-HSA-71286|Reactome:R-HSA-6800149|Reactome:R-HSA-212269|Reactome:R-HSA-379464 go-plus.json methylase http://purl.obolibrary.org/obo/GO_0008168 goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast GO:0008167 biolink:BiologicalProcess obsolete sigma virus replication OBSOLETE. (Was not defined before being made obsolete). go-plus.json sigma virus replication http://purl.obolibrary.org/obo/GO_0008167 GO:0008166 biolink:BiologicalProcess obsolete viral replication OBSOLETE. (Was not defined before being made obsolete). go-plus.json viral replication http://purl.obolibrary.org/obo/GO_0008166 GO:0008165 biolink:BiologicalProcess obsolete pyrethroid resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json pyrethroid resistance http://purl.obolibrary.org/obo/GO_0008165 GO:0008164 biolink:BiologicalProcess obsolete organophosphorus resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json organophosphorus resistance http://purl.obolibrary.org/obo/GO_0008164 GO:0008174 biolink:MolecularActivity mRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0008174 GO:0008173 biolink:MolecularActivity RNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. Reactome:R-HSA-191784 go-plus.json http://purl.obolibrary.org/obo/GO_0008173 GO:0008172 biolink:MolecularActivity S-methyltransferase activity Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule. Reactome:R-HSA-209821|EC:2.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0008172 GO:0008171 biolink:MolecularActivity O-methyltransferase activity Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule. Reactome:R-HSA-5629203|Reactome:R-HSA-5629237|Reactome:R-HSA-6790907|Reactome:R-HSA-5578717|EC:2.1.1.-|Reactome:R-HSA-5629218 go-plus.json http://purl.obolibrary.org/obo/GO_0008171 GO:0008170 biolink:MolecularActivity N-methyltransferase activity Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. EC:2.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0008170 GO:0033127 biolink:BiologicalProcess regulation of histone phosphorylation Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0033127 GO:0033126 biolink:BiologicalProcess obsolete positive regulation of GTP catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. go-plus.json positive regulation of GTP degradation|positive regulation of GTP breakdown|positive regulation of GTP catabolism http://purl.obolibrary.org/obo/GO_0033126 GO:0033125 biolink:BiologicalProcess obsolete negative regulation of GTP catabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. go-plus.json negative regulation of GTP degradation|negative regulation of GTP catabolism|negative regulation of GTP breakdown http://purl.obolibrary.org/obo/GO_0033125 GO:0033124 biolink:BiologicalProcess obsolete regulation of GTP catabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. go-plus.json regulation of GTP catabolism|regulation of GTP degradation|regulation of GTP breakdown http://purl.obolibrary.org/obo/GO_0033124 GO:0033123 biolink:BiologicalProcess positive regulation of purine nucleotide catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. go-plus.json positive regulation of purine nucleotide catabolism|positive regulation of purine nucleotide degradation|positive regulation of purine nucleotide breakdown http://purl.obolibrary.org/obo/GO_0033123 GO:0033122 biolink:BiologicalProcess negative regulation of purine nucleotide catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. go-plus.json negative regulation of purine nucleotide degradation|negative regulation of purine nucleotide breakdown|negative regulation of purine nucleotide catabolism http://purl.obolibrary.org/obo/GO_0033122 GO:0033121 biolink:BiologicalProcess regulation of purine nucleotide catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. go-plus.json regulation of purine nucleotide breakdown|regulation of purine nucleotide catabolism|regulation of purine nucleotide degradation http://purl.obolibrary.org/obo/GO_0033121 GO:0033120 biolink:BiologicalProcess positive regulation of RNA splicing Any process that activates or increases the frequency, rate or extent of RNA splicing. go-plus.json http://purl.obolibrary.org/obo/GO_0033120 GO:0033119 biolink:BiologicalProcess negative regulation of RNA splicing Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing. go-plus.json http://purl.obolibrary.org/obo/GO_0033119 GO:0033118 biolink:CellularComponent esterosome membrane The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0033118 GO:0033117 biolink:CellularComponent esterosome A vesicle filled with crystalline protein that shows sequence similarities with various esterases. go-plus.json http://purl.obolibrary.org/obo/GO_0033117 GO:0008179 biolink:MolecularActivity adenylate cyclase binding Binding to an adenylate cyclase. Reactome:R-HSA-170672 go-plus.json adenylyl cyclase binding http://purl.obolibrary.org/obo/GO_0008179 GO:0008178 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008178 GO:0008177 biolink:MolecularActivity succinate dehydrogenase (ubiquinone) activity Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol. RHEA:13713|MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN|KEGG_REACTION:R02164|EC:1.3.5.1|Reactome:R-HSA-70994|Reactome:R-HSA-163213 go-plus.json respiratory complex II|succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)|menaquinol: fumarate oxidoreductase activity|succinic dehydrogenase activity|fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)|succinate:ubiquinone oxidoreductase activity|quinol:fumarate oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008177 GO:0008176 biolink:MolecularActivity tRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine. MetaCyc:TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|Reactome:R-HSA-6782286|RHEA:42708|EC:2.1.1.33 go-plus.json 7-methylguanine transfer ribonucleate methylase activity|S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity|tRNA guanine 7-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity|transfer ribonucleate guanine 7-methyltransferase activity|N7-methylguanine methylase activity http://purl.obolibrary.org/obo/GO_0008176 GO:0008175 biolink:MolecularActivity tRNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule. Reactome:R-HSA-6783473|Reactome:R-HSA-6782881|Reactome:R-HSA-6782890|Reactome:R-HSA-6786567|Reactome:R-HSA-6786500|Reactome:R-HSA-6782879 go-plus.json http://purl.obolibrary.org/obo/GO_0008175 GO:0008185 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008185 GO:0008184 biolink:MolecularActivity glycogen phosphorylase activity Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate. MetaCyc:GLYCOPHOSPHORYL-RXN|Reactome:R-HSA-453339|Reactome:R-HSA-453358|Reactome:R-HSA-71590|Reactome:R-HSA-71515 go-plus.json http://purl.obolibrary.org/obo/GO_0008184 GO:0008183 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008183 GO:0008182 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008182 GO:0008181 biolink:MolecularActivity obsolete tumor suppressor OBSOLETE. (Was not defined before being made obsolete). go-plus.json tumor suppressor http://purl.obolibrary.org/obo/GO_0008181 GO:0008180 biolink:CellularComponent COP9 signalosome A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. go-plus.json COP9 complex|signalosome|CSN http://purl.obolibrary.org/obo/GO_0008180 GO:0033116 biolink:CellularComponent endoplasmic reticulum-Golgi intermediate compartment membrane The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system. go-plus.json ER-Golgi intermediate compartment membrane http://purl.obolibrary.org/obo/GO_0033116 GO:0033115 biolink:CellularComponent cyanelle thylakoid membrane The lipid bilayer membrane of any thylakoid within a cyanelle. go-plus.json http://purl.obolibrary.org/obo/GO_0033115 GO:0033114 biolink:CellularComponent cyanelle thylakoid lumen The volume enclosed by a cyanelle thylakoid membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0033114 GO:0033113 biolink:CellularComponent cyanelle membrane Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0033113 GO:0033112 biolink:CellularComponent cyanelle envelope The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0033112 GO:0033111 biolink:CellularComponent attachment organelle membrane The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0033111 GO:0033110 biolink:CellularComponent Cvt vesicle membrane Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway. go-plus.json cytoplasm to vacuole targeting vesicle membrane|cytoplasm-to-vacuole targeting vesicle membrane http://purl.obolibrary.org/obo/GO_0033110 GO:0033109 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033109 GO:0033108 biolink:BiologicalProcess mitochondrial respiratory chain complex assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex. go-plus.json http://purl.obolibrary.org/obo/GO_0033108 GO:0033107 biolink:CellularComponent Cvt vesicle A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p). go-plus.json cytoplasm to vacuole targeting vesicle|cytoplasm-to-vacuole targeting vesicle http://purl.obolibrary.org/obo/GO_0033107 GO:0033106 biolink:CellularComponent cis-Golgi network membrane The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. go-plus.json cis Golgi network membrane|Golgi cis face membrane http://purl.obolibrary.org/obo/GO_0033106 GO:0008149 biolink:MolecularActivity obsolete para-aminobenzoic acid (PABA) synthase OBSOLETE. (Was not defined before being made obsolete). go-plus.json para-aminobenzoic acid (PABA) synthase http://purl.obolibrary.org/obo/GO_0008149 GO:0008148 biolink:MolecularActivity obsolete negative transcription elongation factor activity OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation. go-plus.json negative transcription elongation factor activity http://purl.obolibrary.org/obo/GO_0008148 GO:0008147 biolink:MolecularActivity structural constituent of bone The action of a molecule that contributes to the structural integrity of bone. go-plus.json http://purl.obolibrary.org/obo/GO_0008147 GO:0008146 biolink:MolecularActivity sulfotransferase activity Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. EC:2.8.2.-|Reactome:R-HSA-176669|Reactome:R-HSA-176604|Reactome:R-HSA-176588|Reactome:R-HSA-2022061 go-plus.json sulphotransferase activity http://purl.obolibrary.org/obo/GO_0008146 goslim_chembl GO:0008145 biolink:MolecularActivity phenylalkylamine binding Binding to phenylalkylamine or one of its derivatives. go-plus.json http://purl.obolibrary.org/obo/GO_0008145 GO:0008144 biolink:MolecularActivity obsolete drug binding OBSOLETE. Binding to a drug, a naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism;typically used in the diagnosis, prevention, or treatment of disease. go-plus.json http://purl.obolibrary.org/obo/GO_0008144 GO:0008143 biolink:MolecularActivity poly(A) binding Binding to a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA. go-plus.json poly-A binding|poly(rA) binding|poly(A) binding, within an RNA molecule|polyadenylate binding http://purl.obolibrary.org/obo/GO_0008143 GO:0008142 biolink:MolecularActivity oxysterol binding Binding to oxysterol, an oxidized form of cholesterol. go-plus.json http://purl.obolibrary.org/obo/GO_0008142 GO:0008152 biolink:BiologicalProcess metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. Wikipedia:Metabolism go-plus.json metabolism|metabolic process resulting in cell growth|metabolism resulting in cell growth|multicellular organism metabolic process|single-organism metabolic process http://purl.obolibrary.org/obo/GO_0008152 goslim_chembl|gocheck_do_not_manually_annotate|goslim_pir|goslim_plant|goslim_metagenomics GO:0008151 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008151 GO:0008150 biolink:BiologicalProcess biological_process A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. Wikipedia:Biological_process go-plus.json biological process|single-organism process|physiological process|single organism process http://purl.obolibrary.org/obo/GO_0008150 goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe GO:0033105 biolink:CellularComponent chlorosome envelope The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome. go-plus.json chlorosome membrane http://purl.obolibrary.org/obo/GO_0033105 GO:0033104 biolink:CellularComponent type VI protein secretion system complex A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence. go-plus.json T6SS complex http://purl.obolibrary.org/obo/GO_0033104 GO:0033103 biolink:BiologicalProcess protein secretion by the type VI secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence. go-plus.json protein secretion by the type VI protein secretion system|type VI protein secretion system|protein secretion by the T6SS http://purl.obolibrary.org/obo/GO_0033103 GO:0033102 biolink:CellularComponent acidocalcisome membrane The lipid bilayer surrounding an acidocalcisome. go-plus.json http://purl.obolibrary.org/obo/GO_0033102 GO:0033101 biolink:CellularComponent cellular bud membrane The portion of the plasma membrane surrounding a cellular bud. go-plus.json cellular bud plasma membrane http://purl.obolibrary.org/obo/GO_0033101 GO:0033100 biolink:CellularComponent NuA3 histone acetyltransferase complex A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p. go-plus.json http://purl.obolibrary.org/obo/GO_0033100 GO:0008159 biolink:MolecularActivity obsolete positive transcription elongation factor activity OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation. go-plus.json positive transcription elongation factor activity http://purl.obolibrary.org/obo/GO_0008159 GO:0008158 biolink:MolecularActivity hedgehog receptor activity Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity. go-plus.json patched activity http://purl.obolibrary.org/obo/GO_0008158 GO:0008157 biolink:MolecularActivity protein phosphatase 1 binding Binding to a protein phosphatase 1. go-plus.json http://purl.obolibrary.org/obo/GO_0008157 GO:0008156 biolink:BiologicalProcess negative regulation of DNA replication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication. go-plus.json down regulation of DNA replication|downregulation of DNA replication|DNA replication inhibitor|down-regulation of DNA replication|inhibition of DNA replication http://purl.obolibrary.org/obo/GO_0008156 GO:0008155 biolink:BiologicalProcess obsolete larval behavior (sensu Drosophila) OBSOLETE. (Was not defined before being made obsolete). go-plus.json larval behavior (sensu Drosophila) http://purl.obolibrary.org/obo/GO_0008155 GO:0008154 biolink:BiologicalProcess actin polymerization or depolymerization Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. go-plus.json http://purl.obolibrary.org/obo/GO_0008154 GO:0008153 biolink:BiologicalProcess para-aminobenzoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins. go-plus.json para-aminobenzoic acid anabolism|para-aminobenzoic acid synthesis|p-aminobenzoic acid biosynthetic process|vitamin Bx biosynthesis|p-aminobenzoic acid biosynthesis|vitamin Bx biosynthetic process|para-aminobenzoic acid formation|4-aminobenzoic acid biosynthetic process|4-aminobenzoic acid biosynthesis|PABA biosynthetic process|PABA biosynthesis|para-aminobenzoic acid biosynthesis http://purl.obolibrary.org/obo/GO_0008153 GO:0008163 biolink:BiologicalProcess obsolete DDT resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json DDT resistance http://purl.obolibrary.org/obo/GO_0008163 GO:0008162 biolink:BiologicalProcess obsolete cyclodiene resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json cyclodiene resistance http://purl.obolibrary.org/obo/GO_0008162 GO:0008161 biolink:BiologicalProcess obsolete carbamate resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json carbamate resistance http://purl.obolibrary.org/obo/GO_0008161 GO:0008160 biolink:MolecularActivity protein tyrosine phosphatase activator activity Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0008160 GO:0008129 biolink:MolecularActivity obsolete actinidain activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'. go-plus.json actinidin activity|actinidain activity|proteinase A2 of actinidia chinensis|actinidia anionic protease activity http://purl.obolibrary.org/obo/GO_0008129 GO:0008128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008128 GO:0008127 biolink:MolecularActivity quercetin 2,3-dioxygenase activity Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO. KEGG_REACTION:R02156|RHEA:15381|EC:1.13.11.24|MetaCyc:QUERCETIN-23-DIOXYGENASE-RXN|Reactome:R-HSA-8953398|UM-BBD_reactionID:r0891 go-plus.json flavonol 2,4-oxygenase activity|quercetin:oxygen 2,3-oxidoreductase (decyclizing)|quercetinase activity http://purl.obolibrary.org/obo/GO_0008127 GO:0008126 biolink:MolecularActivity acetylesterase activity Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate. UM-BBD_reactionID:r0170|EC:3.1.1.6|RHEA:12957|MetaCyc:ACETYLESTERASE-RXN go-plus.json C-esterase (in animal tissues)|p-nitrophenyl acetate esterase|acetic ester hydrolase activity|chloroesterase|citrus acetylesterase|acetic-ester acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0008126 GO:0008125 biolink:MolecularActivity obsolete pancreatic elastase I activity OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa. go-plus.json pancreatopeptidase E activity|pancreatic elastase I activity|elaszym|serine elastase http://purl.obolibrary.org/obo/GO_0008125 CHEBI:2937 biolink:ChemicalSubstance avenacoside A go-plus.json http://purl.obolibrary.org/obo/CHEBI_2937 chebi_ph7_3 GO:0008124 biolink:MolecularActivity 4-alpha-hydroxytetrahydrobiopterin dehydratase activity Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O. MetaCyc:RXN-7908|Reactome:R-HSA-71146|RHEA:11920|KEGG_REACTION:R04734|EC:4.2.1.96 go-plus.json pterin-4-alpha-carbinolamine dehydratase activity|4a-hydroxytetrahydrobiopterin dehydratase activity|4alpha-hydroxy-tetrahydropterin dehydratase activity|4a-hydroxytetrahydrobiopterin hydro-lyase activity|4-alpha-hydroxy-tetrahydropterin dehydratase activity|pterin-4a-carbinolamine dehydratase activity|pterin-4alpha-carbinolamine dehydratase activity|(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]|tetrahydrobiopterin dehydratase activity http://purl.obolibrary.org/obo/GO_0008124 GO:0008123 biolink:MolecularActivity cholesterol 7-alpha-monooxygenase activity Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O. EC:1.14.14.23|Reactome:R-HSA-192051|MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN|RHEA:21812 go-plus.json cholesterol 7alpha-monooxygenase activity|cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|cholesterol 7alpha-hydroxylase activity|cytochrome P450 CYP7A1|cholesterol 7-alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0008123 CHEBI:2938 biolink:ChemicalSubstance avenacoside B go-plus.json http://purl.obolibrary.org/obo/CHEBI_2938 chebi_ph7_3 GO:0008122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008122 GO:0008121 biolink:MolecularActivity ubiquinol-cytochrome-c reductase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+. RHEA:11484|Reactome:R-HSA-164651|MetaCyc:1.10.2.2-RXN|EC:7.1.1.8 go-plus.json cytochrome b562|cytochrome c1|electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity|ubiquinone--cytochrome-c oxidoreductase activity|cytochrome|soluble cytochrome b562|ubiquinone-cytochrome c reductase activity|ubiquinone-cytochrome c oxidoreductase activity|cytochrome a3/copper complex|ubiquinol-cytochrome c-2 oxidoreductase activity|mitochondrial electron transport complex III|complex III (mitochondrial electron transport) activity|ubiquinol-cytochrome c2 reductase activity|cytochrome a|electron transporter, transferring electrons within cytochrome c oxidase complex activity|ubiquinol-cytochrome c oxidoreductase activity|ubiquinol-cytochrome c1 oxidoreductase activity|cytochrome b566|ubiquinol:ferricytochrome-c oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008121 GO:0008120 biolink:MolecularActivity ceramide glucosyltransferase activity Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. EC:2.4.1.80|RHEA:12088|Reactome:R-HSA-1638104|MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN go-plus.json UDP-glucose:N-acylsphingosine D-glucosyltransferase activity|ceramide:UDP-glucose glucosyltransferase activity|UDP-glucose-ceramide glucosyltransferase activity|UDPglucose:N-acylsphingosine D-glucosyltransferase activity|glucosylceramide synthase activity|UDP-glucose:ceramide glucosyltransferase activity|ceramide:UDPGlc glucosyltransferase activity|uridine diphosphoglucose-ceramide glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0008120 GO:0008130 biolink:MolecularActivity obsolete neutrophil collagenase activity OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I. go-plus.json PMNL collagenase activity|matrix metalloproteinase 8 activity|neutrophil collagenase activity|MMP-8 http://purl.obolibrary.org/obo/GO_0008130 CHEBI:143624 biolink:ChemicalSubstance D-galactofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_143624 chebi_ph7_3 CHEBI:73500 biolink:ChemicalSubstance 3-hydroxy-3-(4-hydroxyphenyl)propionyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73500 chebi_ph7_3 CHEBI:73504 biolink:ChemicalSubstance (9Z)-octadecen-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73504 chebi_ph7_3 GO:0008139 biolink:MolecularActivity nuclear localization sequence binding Binding to a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus. go-plus.json NLS binding|nuclear localization signal binding|nuclear localisation sequence binding http://purl.obolibrary.org/obo/GO_0008139 GO:0008138 biolink:MolecularActivity protein tyrosine/serine/threonine phosphatase activity Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate. Reactome:R-HSA-5675376|Reactome:R-HSA-5675373|Reactome:R-HSA-9652816 go-plus.json dual-specificity protein phosphatase http://purl.obolibrary.org/obo/GO_0008138 GO:0008137 biolink:MolecularActivity NADH dehydrogenase (ubiquinone) activity Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out). Reactome:R-HSA-163217|MetaCyc:RXN0-5330|MetaCyc:NADH-DEHYDROG-A-RXN|EC:7.1.1.2|RHEA:29091 go-plus.json type 1 dehydrogenase activity|dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity|NADH:ubiquinone oxidoreductase complex activity|NADH-coenzyme Q oxidoreductase activity|electron transfer complex I activity|DPNH-coenzyme Q reductase activity|NADH-CoQ oxidoreductase activity|DPNH-ubiquinone reductase activity|ubiquinone reductase activity|complex I (mitochondrial electron transport) activity|NADH coenzyme Q1 reductase activity|NADH-CoQ reductase activity|NADH:ubiquinone oxidoreductase activity|mitochondrial electron transport complex I activity|NADH-coenzyme Q reductase activity|complex 1 dehydrogenase activity|NADH-ubiquinone reductase activity|reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity|mitochondrial electron transport complex 1 activity|NADH-Q6 oxidoreductase activity|complex I (NADH:Q1 oxidoreductase) activity|NADH-ubiquinone-1 reductase activity|coenzyme Q reductase activity|NADH-ubiquinone oxidoreductase activity|complex I (electron transport chain) activity http://purl.obolibrary.org/obo/GO_0008137 GO:0008136 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008136 GO:0008135 biolink:MolecularActivity translation factor activity, RNA binding Functions during translation by binding to RNA during polypeptide synthesis at the ribosome. go-plus.json translation factor activity, nucleic acid binding http://purl.obolibrary.org/obo/GO_0008135 goslim_chembl|goslim_yeast|goslim_plant|goslim_generic GO:0008134 biolink:MolecularActivity transcription factor binding Binding to a transcription factor, a protein required to initiate or regulate transcription. go-plus.json TF binding http://purl.obolibrary.org/obo/GO_0008134 goslim_chembl|goslim_yeast|goslim_agr|gocheck_do_not_annotate|goslim_drosophila|goslim_metagenomics|goslim_generic GO:0008133 biolink:MolecularActivity obsolete collagenase activity OBSOLETE. Was not defined before being made obsolete. go-plus.json collagenase activity http://purl.obolibrary.org/obo/GO_0008133 GO:0008132 biolink:MolecularActivity obsolete pancreatic elastase activity OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. go-plus.json pancreatic elastase activity http://purl.obolibrary.org/obo/GO_0008132 GO:0008131 biolink:MolecularActivity primary amine oxidase activity Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide. Reactome:R-HSA-379395|MetaCyc:RXN-9597|KEGG_REACTION:R01853|EC:1.4.3.21|Reactome:R-HSA-141186|Reactome:R-HSA-5696183|Reactome:R-HSA-374909|Reactome:R-HSA-379382|Reactome:R-HSA-5603108|Reactome:R-HSA-141200|Reactome:R-HSA-5696146|Reactome:R-HSA-141202 go-plus.json amine oxidase activity|amine oxidase (copper-containing) activity|primary-amine:oxygen oxidoreductase (deaminating) activity http://purl.obolibrary.org/obo/GO_0008131 GO:0008141 biolink:MolecularActivity obsolete puparial glue (sensu Diptera) OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147). go-plus.json puparial glue (sensu Diptera) http://purl.obolibrary.org/obo/GO_0008141 GO:0008140 biolink:MolecularActivity cAMP response element binding protein binding Binding to a cAMP response element binding protein (a CREB protein). go-plus.json CBP|3',5' cAMP response element binding protein binding|CREB binding|cyclic AMP response element binding protein binding|adenosine 3',5'-cyclophosphate response element binding protein binding|3',5'-cAMP response element binding protein binding http://purl.obolibrary.org/obo/GO_0008140 GO:0008109 biolink:MolecularActivity N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R. RHEA:17413|MetaCyc:2.4.1.150-RXN|EC:2.4.1.150 go-plus.json uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity|UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity|galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0008109 GO:0008108 biolink:MolecularActivity UDP-glucose:hexose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose. EC:2.7.7.12|Reactome:R-HSA-5610038|Reactome:R-HSA-70361|KEGG_REACTION:R00955|MetaCyc:GALACTURIDYLYLTRANS-RXN|RHEA:13989 go-plus.json UDPglucose-hexose-1-phosphate uridylyltransferase activity|hexose 1-phosphate uridyltransferase activity|hexose-1-phosphate uridylyltransferase activity|galactose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|UDP-glucose-hexose-1-phosphate uridylyltransferase activity|UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|uridyl transferase activity|UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|uridylyl removing enzyme activity|uridyltransferase activity http://purl.obolibrary.org/obo/GO_0008108 GO:0008107 biolink:MolecularActivity galactoside 2-alpha-L-fucosyltransferase activity Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R. MetaCyc:GALACTOSIDE-2-L-FUCOSYLTRANSFERASE-RXN|Reactome:R-HSA-9036987|Reactome:R-HSA-9603983|EC:2.4.1.69|RHEA:50664|Reactome:R-HSA-9603982 go-plus.json secretor-type beta-galactoside alpha1->2 fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity|blood group H alpha-2-fucosyltransferase activity|blood-group substance H-dependent fucosyltransferase activity|guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity|H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity|H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity|guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity|beta-galactoside alpha1->2 fucosyltransferase activity|beta-galactoside alpha-1->2 fucosyltransferase activity|alpha-2-fucosyltransferase activity|alpha-2-L-fucosyltransferase activity|secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity|alpha(1,2)-L-fucosyltransferase activity|guanosine diphosphofucose-lactose fucosyltransferase activity|guanosine diphospho-L-fucose-lactose fucosyltransferase activity|alpha-(1->2)-L-fucosyltransferase activity|GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity|galactoside 2-L-fucosyltransferase activity|GDP-L-fucose:lactose fucosyltransferase activity|GDP fucose-lactose fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0008107 GO:0008106 biolink:MolecularActivity alcohol dehydrogenase (NADP+) activity Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+. EC:1.1.1.2|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN|RHEA:15937 go-plus.json NADP-aldehyde reductase activity|aldehyde reductase (NADPH) activity|aldehyde reductase (NADPH2) activity|alcohol:NADP dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008106 CHEBI:48591 biolink:ChemicalSubstance N-acylpiperidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48591 GO:0008105 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008105 GO:0008104 biolink:BiologicalProcess protein localization Any process in which a protein is transported to, or maintained in, a specific location. go-plus.json asymmetric protein localisation|asymmetric protein localization|establishment and maintenance of protein localization|protein localisation|establishment and maintenance of asymmetric protein localization http://purl.obolibrary.org/obo/GO_0008104 CHEBI:48590 biolink:ChemicalSubstance hydroxypiperidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48590 GO:0008103 biolink:BiologicalProcess oocyte microtubule cytoskeleton polarization Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0008103 GO:0008102 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008102 CHEBI:48592 biolink:ChemicalSubstance piperidinecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_48592 CHEBI:48595 biolink:ChemicalSubstance 5'-S-methyl-5'-thioinosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48595 chebi_ph7_3 GO:0008101 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008101 GO:0008100 biolink:MolecularActivity obsolete lipophorin OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects. go-plus.json lipophorin http://purl.obolibrary.org/obo/GO_0008100 CHEBI:48597 biolink:ChemicalSubstance arsenate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48597 chebi_ph7_3 CHEBI:48589 biolink:ChemicalSubstance piperidones go-plus.json http://purl.obolibrary.org/obo/CHEBI_48589 GO:0008119 biolink:MolecularActivity thiopurine S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN|Reactome:R-HSA-5603379|EC:2.1.1.67|Reactome:R-HSA-158609 go-plus.json TPMT|mercaptopurine methyltransferase activity|thiopurine methyltransferase activity|S-adenosyl-L-methionine:thiopurine S-methyltransferase activity|6-thiopurine transmethylase activity http://purl.obolibrary.org/obo/GO_0008119 GO:0008118 biolink:MolecularActivity N-acetyllactosaminide alpha-2,3-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein. EC:2.4.99.6|RHEA:52316|MetaCyc:2.4.99.6-RXN go-plus.json SiaT|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity|alpha2->3 sialyltransferase activity http://purl.obolibrary.org/obo/GO_0008118 GO:0008117 biolink:MolecularActivity sphinganine-1-phosphate aldolase activity Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde. Reactome:R-HSA-428676|Reactome:R-HSA-428681|EC:4.1.2.27|MetaCyc:SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN|RHEA:18593 go-plus.json sphinganine-1-phosphate lyase activity|sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)|sphingosine-1-phosphate lyase activity|dihydrosphingosine 1-phosphate aldolase activity|sphinganine-1-phosphate alkanal-lyase activity|sphingosine-1-phosphate aldolase activity|sphinganine-1-phosphate palmitaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0008117 GO:0008116 biolink:MolecularActivity prostaglandin-I synthase activity Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2). EC:5.3.99.4|MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN|KEGG_REACTION:R02267|Reactome:R-HSA-76496|RHEA:23580 go-plus.json PGI(2) synthase activity|PGI2 synthase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity|prostacycline synthetase activity|PGI(2) synthetase activity|prostagladin I2 synthetase activity|prostacyclin synthase activity|cytochrome P450 CYP8A1|PGI2 synthetase activity http://purl.obolibrary.org/obo/GO_0008116 GO:0008115 biolink:MolecularActivity sarcosine oxidase activity Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2). MetaCyc:SARCOX-RXN|KEGG_REACTION:R00610|RHEA:13313|EC:1.5.3.1 go-plus.json sarcosine:oxygen oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0008115 GO:0008114 biolink:MolecularActivity phosphogluconate 2-dehydrogenase activity Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH. EC:1.1.1.43|MetaCyc:1.1.1.43-RXN go-plus.json 6-phosphogluconate 2-dehydrogenase activity|2-keto-6-phosphogluconate reductase activity|phosphogluconate dehydrogenase activity|gluconate 6-phosphate dehydrogenase activity|6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity|6-phosphogluconate dehydrogenase (NAD)|6-phosphogluconic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008114 CHEBI:48582 biolink:ChemicalSubstance ADP-D-ribose 1'',2''-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48582 GO:0008113 biolink:MolecularActivity peptide-methionine (S)-S-oxide reductase activity Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. MetaCyc:RXN-8669|MetaCyc:RXN-8668|RHEA:14217|Reactome:R-HSA-5676940|EC:1.8.4.11|Reactome:R-HSA-1222363 go-plus.json methionine sulfoxide (protein) reductase activity|MsrA|methionine sulphoxide reductase A activity|methionine sulfoxide reductase A activity|protein-methionine-S-oxide reductase activity|peptide-methionine-(S)-S-oxide reductase activity|methionine sulfoxide reductase activity|methionine S-oxide reductase (S-form oxidizing) activity|methionine S-oxide reductase activity|peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity|peptide Met(O) reductase activity|peptide methionine sulfoxide reductase activity http://purl.obolibrary.org/obo/GO_0008113 GO:0008112 biolink:MolecularActivity nicotinamide N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine. MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01269|RHEA:23884|Reactome:R-HSA-5359451|EC:2.1.1.1 go-plus.json nicotinamide methyltransferase activity|S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008112 CHEBI:48584 biolink:ChemicalSubstance ADP-D-ribose 1''-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48584 GO:0008111 biolink:MolecularActivity alpha-methylacyl-CoA racemase activity Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA. EC:5.1.99.4|Reactome:R-HSA-193763|RHEA:12657|MetaCyc:5.1.99.4-RXN|Reactome:R-HSA-389897|Reactome:R-HSA-192056|Reactome:R-HSA-193452|Reactome:R-HSA-193736 go-plus.json 2-methylacyl-CoA 2-epimerase activity http://purl.obolibrary.org/obo/GO_0008111 GO:0008110 biolink:MolecularActivity L-histidine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate. EC:2.6.1.38|RHEA:16565|KEGG_REACTION:R01161|MetaCyc:HISTTRANSAM-RXN go-plus.json histidine transaminase activity|histidine aminotransferase activity|histidine-2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0008110 CHEBI:48585 biolink:ChemicalSubstance heteroarylpiperidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48585 GO:0072694 biolink:BiologicalProcess obsolete cell cycle arrest in response to caffeine OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a caffeine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072694 GO:0072693 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072693 GO:0072692 biolink:BiologicalProcess obsolete chromatin silencing at centromere central core OBSOLETE. Repression of transcription of DNA at the central core of a regional centromere by altering the structure of chromatin. go-plus.json chromatin silencing at chromosome kinetochore domain|heterochromatic silencing at centromere central core|chromatin silencing at centromeric central core|centromere central core chromatin silencing http://purl.obolibrary.org/obo/GO_0072692 GO:0072691 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072691 GO:0072690 biolink:BiologicalProcess single-celled organism vegetative growth phase A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods. go-plus.json stationary phase|vegetative growth of a single-celled organism http://purl.obolibrary.org/obo/GO_0072690 gocheck_do_not_annotate CHEBI:2979 biolink:ChemicalSubstance baicalein go-plus.json http://purl.obolibrary.org/obo/CHEBI_2979 GO:0033086 biolink:BiologicalProcess negative regulation of extrathymic T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation. go-plus.json negative regulation of extrathymic T cell development http://purl.obolibrary.org/obo/GO_0033086 GO:0033085 biolink:BiologicalProcess negative regulation of T cell differentiation in thymus Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. go-plus.json negative regulation of thymocyte cell differentiation|negative regulation of thymocyte differentiation|negative regulation of T cell development in thymus|negative regulation of thymic T cell differentiation http://purl.obolibrary.org/obo/GO_0033085 GO:0033084 biolink:BiologicalProcess regulation of immature T cell proliferation in thymus Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus. go-plus.json regulation of thymocyte proliferation|regulation of thymic T cell proliferation|regulation of thymocyte cell proliferation http://purl.obolibrary.org/obo/GO_0033084 GO:0033083 biolink:BiologicalProcess regulation of immature T cell proliferation Any process that modulates the frequency, rate or extent of immature T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0033083 NCBITaxon:513050 biolink:OrganismalEntity Dictyoglomus turgidum go-plus.json Dictyoglomus turgidus http://purl.obolibrary.org/obo/NCBITaxon_513050 GO:0033082 biolink:BiologicalProcess regulation of extrathymic T cell differentiation Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation. go-plus.json regulation of extrathymic T cell development http://purl.obolibrary.org/obo/GO_0033082 GO:0033081 biolink:BiologicalProcess regulation of T cell differentiation in thymus Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. go-plus.json regulation of thymocyte cell differentiation|regulation of T cell development in thymus|regulation of thymocyte differentiation|regulation of thymic T cell differentiation http://purl.obolibrary.org/obo/GO_0033081 GO:0033080 biolink:BiologicalProcess immature T cell proliferation in thymus The expansion of an immature T cell population by cell division in the thymus. go-plus.json thymocyte cell proliferation|thymocyte proliferation|thymic T cell proliferation http://purl.obolibrary.org/obo/GO_0033080 GO:0072699 biolink:BiologicalProcess protein localization to cortical microtubule cytoskeleton A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton. go-plus.json protein localisation to cortical microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0072699 GO:0072698 biolink:BiologicalProcess protein localization to microtubule cytoskeleton A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. go-plus.json protein localisation to microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0072698 GO:0072697 biolink:BiologicalProcess protein localization to cell cortex A process in which a protein is transported to, or maintained in, the cell cortex. go-plus.json protein localisation to cell cortex http://purl.obolibrary.org/obo/GO_0072697 GO:0033089 biolink:BiologicalProcess positive regulation of T cell differentiation in thymus Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. go-plus.json positive regulation of T cell development in thymus|positive regulation of thymocyte differentiation|positive regulation of thymic T cell differentiation|positive regulation of thymocyte cell differentiation http://purl.obolibrary.org/obo/GO_0033089 GO:0033088 biolink:BiologicalProcess negative regulation of immature T cell proliferation in thymus Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus. go-plus.json negative regulation of thymocyte cell proliferation|negative regulation of thymocyte proliferation|negative regulation of thymic T cell proliferation http://purl.obolibrary.org/obo/GO_0033088 GO:0072696 biolink:BiologicalProcess positive regulation of DNA recombination at telomere Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere. go-plus.json upregulation of telomeric recombination at telomere|up regulation of telomeric recombination at telomere|activation of telomeric recombination at telomere|up-regulation of telomeric recombination at telomere|positive regulation of telomeric recombination http://purl.obolibrary.org/obo/GO_0072696 GO:0033087 biolink:BiologicalProcess negative regulation of immature T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0033087 GO:0072695 biolink:BiologicalProcess regulation of DNA recombination at telomere Any process that modulates the frequency, rate or extent of DNA recombination within the telomere. go-plus.json regulation of telomeric recombination http://purl.obolibrary.org/obo/GO_0072695 GO:0072683 biolink:BiologicalProcess T cell extravasation The migration of a T cell from the blood vessels into the surrounding tissue. go-plus.json T lymphocyte extravasation|T-cell extravasation|T-lymphocyte extravasation http://purl.obolibrary.org/obo/GO_0072683 GO:0072682 biolink:BiologicalProcess eosinophil extravasation The migration of an eosinophil from the blood vessels into the surrounding tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0072682 GO:0072681 biolink:BiologicalProcess fibronectin-dependent thymocyte migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix. go-plus.json fibronectin-dependent immature T-cell migration|fibronectin-dependent immature T-lymphocyte migration|fibronectin-dependent immature T cell migration|fibronectin-dependent thymic lymphocyte migration|fibronectin-dependent immature T lymphocyte migration http://purl.obolibrary.org/obo/GO_0072681 GO:0072680 biolink:BiologicalProcess extracellular matrix-dependent thymocyte migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin. go-plus.json extracellular matrix-dependent immature T lymphocyte migration|extracellular matrix-dependent immature T-cell migration|extracellular matrix-dependent immature T-lymphocyte migration|extracellular matrix-dependent immature T cell migration|extracellular matrix-dependent thymic lymphocyte migration http://purl.obolibrary.org/obo/GO_0072680 GO:0033075 biolink:BiologicalProcess isoquinoline alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin. go-plus.json isoquinoline alkaloid synthesis|isoquinoline alkaloid formation|ipecac alkaloid biosynthesis|isoquinoline alkaloid anabolism|isoquinoline alkaloid biosynthesis http://purl.obolibrary.org/obo/GO_0033075 GO:0033074 biolink:BiologicalProcess pinene catabolic process The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane. go-plus.json pinene degradation|pinene breakdown|pinene catabolism http://purl.obolibrary.org/obo/GO_0033074 CHEBI:2981 biolink:ChemicalSubstance baicalin go-plus.json http://purl.obolibrary.org/obo/CHEBI_2981 GO:0033073 biolink:BiologicalProcess pinene metabolic process The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane. go-plus.json pinene metabolism http://purl.obolibrary.org/obo/GO_0033073 GO:0033072 biolink:BiologicalProcess vancomycin biosynthetic process The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria. go-plus.json vancomycin biosynthesis|vancomycin formation|vancomycin anabolism|vancomycin synthesis http://purl.obolibrary.org/obo/GO_0033072 GO:0033071 biolink:BiologicalProcess vancomycin metabolic process The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria. go-plus.json vancomycin metabolism http://purl.obolibrary.org/obo/GO_0033071 GO:0033070 biolink:BiologicalProcess ansamycin biosynthetic process The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity. go-plus.json ansamycin anabolism|ansamycin synthesis|ansamycin formation|ansamycin biosynthesis http://purl.obolibrary.org/obo/GO_0033070 GO:0072689 biolink:BiologicalProcess MCM complex assembly The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0072689 GO:0072688 biolink:BiologicalProcess SHREC complex localization Any process in which a SHREC complex is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of SHREC complex localization|SHREC complex localisation http://purl.obolibrary.org/obo/GO_0072688 GO:0072687 biolink:CellularComponent meiotic spindle A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0072687 GO:0033079 biolink:BiologicalProcess immature T cell proliferation The expansion of an immature T cell population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0033079 GO:0033078 biolink:BiologicalProcess extrathymic T cell differentiation The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus. go-plus.json extrathymic T cell development http://purl.obolibrary.org/obo/GO_0033078 GO:0072686 biolink:CellularComponent mitotic spindle A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0072686 GO:0072685 biolink:BiologicalProcess Mre11 complex assembly The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling. go-plus.json Rad50-Rad32-Nbs1 complex assembly|MRN complex assembly|Rad50 complex assembly|MRX complex assembly|RMX complex assembly|RAD50-MRE11-NBN complex assembly http://purl.obolibrary.org/obo/GO_0072685 GO:0033077 biolink:BiologicalProcess T cell differentiation in thymus The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. go-plus.json thymocyte cell differentiation|T cell development in thymus|thymocyte differentiation|thymic T cell differentiation http://purl.obolibrary.org/obo/GO_0033077 GO:0072684 biolink:BiologicalProcess mitochondrial tRNA 3'-trailer cleavage, endonucleolytic Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion. go-plus.json mitochondrial tRNA 3'-end cleavage, endonucleolytic|mitochondrial endonucleolytic tRNA 3'-trailer cleavage|mitochondrial endonucleolytic tRNA 3'-end cleavage http://purl.obolibrary.org/obo/GO_0072684 GO:0033076 biolink:BiologicalProcess isoquinoline alkaloid metabolic process The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin. go-plus.json isoquinoline alkaloid metabolism|ipecac alkaloid metabolism http://purl.obolibrary.org/obo/GO_0033076 GO:0033064 biolink:CellularComponent XRCC2-RAD51D complex A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast. go-plus.json DX2 complex http://purl.obolibrary.org/obo/GO_0033064 GO:0033063 biolink:CellularComponent Rad51B-Rad51C-Rad51D-XRCC2 complex A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof. go-plus.json BCDX2 complex http://purl.obolibrary.org/obo/GO_0033063 GO:0033062 biolink:CellularComponent Rhp55-Rhp57 complex A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces). go-plus.json Rad55-Rad57 complex http://purl.obolibrary.org/obo/GO_0033062 GO:0033061 biolink:CellularComponent DNA recombinase mediator complex A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange. go-plus.json http://purl.obolibrary.org/obo/GO_0033061 goslim_pir GO:0033060 biolink:BiologicalProcess ocellus pigmentation The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0033060 GO:0033069 biolink:BiologicalProcess ansamycin metabolic process The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity. go-plus.json ansamycin metabolism http://purl.obolibrary.org/obo/GO_0033069 GO:0033068 biolink:BiologicalProcess macrolide biosynthetic process The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria. go-plus.json macrolide anabolism|macrolide biosynthesis|macrolide synthesis|macrolide formation http://purl.obolibrary.org/obo/GO_0033068 GO:0033067 biolink:BiologicalProcess macrolide metabolic process The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria. go-plus.json macrolide metabolism http://purl.obolibrary.org/obo/GO_0033067 GO:0033066 biolink:CellularComponent Rad51B-Rad51C complex A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof. go-plus.json BC complex http://purl.obolibrary.org/obo/GO_0033066 GO:0033065 biolink:CellularComponent Rad51C-XRCC3 complex A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof. go-plus.json CX3 complex http://purl.obolibrary.org/obo/GO_0033065 GO:0033053 biolink:BiologicalProcess D-glutamine metabolic process The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid. go-plus.json D-glutamine metabolism http://purl.obolibrary.org/obo/GO_0033053 GO:0033052 biolink:BiologicalProcess cyanoamino acid metabolic process The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group. go-plus.json cyanoamino acid metabolism http://purl.obolibrary.org/obo/GO_0033052 GO:0033051 biolink:BiologicalProcess aminophosphonate metabolic process The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group. KEGG_PATHWAY:map00440 go-plus.json aminophosphonate metabolism http://purl.obolibrary.org/obo/GO_0033051 GO:0033050 biolink:BiologicalProcess clavulanic acid biosynthetic process The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Wikipedia:Clavulanic_acid go-plus.json clavulanic acid anabolism|clavulanic acid synthesis|clavulanic acid formation|clavulanic acid biosynthesis http://purl.obolibrary.org/obo/GO_0033050 GO:0033059 biolink:BiologicalProcess cellular pigmentation The deposition or aggregation of coloring matter in a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0033059 GO:0033058 biolink:BiologicalProcess directional locomotion Self-propelled movement of a cell or organism from one location to another along an axis. go-plus.json http://purl.obolibrary.org/obo/GO_0033058 GO:0033057 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033057 GO:0033056 biolink:BiologicalProcess D-ornithine metabolic process The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid. go-plus.json D-ornithine metabolism http://purl.obolibrary.org/obo/GO_0033056 GO:0033055 biolink:BiologicalProcess D-arginine metabolic process The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid. go-plus.json D-arginine metabolism http://purl.obolibrary.org/obo/GO_0033055 GO:0033054 biolink:BiologicalProcess D-glutamate metabolic process The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid. go-plus.json D-glutamate metabolism http://purl.obolibrary.org/obo/GO_0033054 GO:0008089 biolink:BiologicalProcess anterograde axonal transport The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons. go-plus.json anterograde axon cargo transport http://purl.obolibrary.org/obo/GO_0008089 goslim_synapse GO:0008088 biolink:BiologicalProcess axo-dendritic transport The directed movement of organelles or molecules along microtubules in neuron projections. Wikipedia:Axoplasmic_transport go-plus.json axon cargo transport|axoplasmic transport|axonal transport http://purl.obolibrary.org/obo/GO_0008088 goslim_synapse GO:0008087 biolink:CellularComponent light-activated voltage-gated calcium channel complex A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus. go-plus.json light-activated voltage-dependent calcium channel complex|light-activated voltage-sensitive calcium channel complex|light-activated voltage gated calcium channel complex http://purl.obolibrary.org/obo/GO_0008087 GO:0008097 biolink:MolecularActivity 5S rRNA binding Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0008097 GO:0033042 biolink:MolecularActivity umami taste receptor activity Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates. go-plus.json http://purl.obolibrary.org/obo/GO_0033042 GO:0008096 biolink:MolecularActivity juvenile hormone epoxide hydrolase activity Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol. EC:3.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0008096 GO:0033041 biolink:MolecularActivity sweet taste receptor activity Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste. go-plus.json http://purl.obolibrary.org/obo/GO_0033041 GO:0033040 biolink:MolecularActivity sour taste receptor activity Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste. go-plus.json http://purl.obolibrary.org/obo/GO_0033040 GO:0008095 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008095 GO:0008094 biolink:MolecularActivity ATP-dependent activity, acting on DNA Catalytic activity that acts to modify DNA, driven by ATP hydrolysis. go-plus.json DNA-dependent adenosinetriphosphatase activity|DNA dependent ATPase activity|DNA-dependent ATPase activity|ATPase, acting on DNA|ATPase activity, acting on DNA|adenosinetriphosphatase (DNA-dependent) http://purl.obolibrary.org/obo/GO_0008094 GO:0008093 biolink:MolecularActivity cytoskeletal anchor activity The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, spindle pole body, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way. go-plus.json cytoskeletal adaptor activity http://purl.obolibrary.org/obo/GO_0008093 GO:0008092 biolink:MolecularActivity cytoskeletal protein binding Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). go-plus.json http://purl.obolibrary.org/obo/GO_0008092 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_drosophila|goslim_generic GO:0008091 biolink:CellularComponent spectrin Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins. Wikipedia:Spectrin|NIF_Subcellular:sao536287099 go-plus.json http://purl.obolibrary.org/obo/GO_0008091 GO:0008090 biolink:BiologicalProcess retrograde axonal transport The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons. go-plus.json retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_0008090 goslim_synapse GO:0033049 biolink:BiologicalProcess clavulanic acid metabolic process The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. go-plus.json clavulanic acid metabolism http://purl.obolibrary.org/obo/GO_0033049 GO:0033048 biolink:BiologicalProcess negative regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0033048 GO:0033047 biolink:BiologicalProcess regulation of mitotic sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0033047 GO:0033046 biolink:BiologicalProcess negative regulation of sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. go-plus.json http://purl.obolibrary.org/obo/GO_0033046 GO:0033045 biolink:BiologicalProcess regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation. go-plus.json http://purl.obolibrary.org/obo/GO_0033045 GO:0033044 biolink:BiologicalProcess regulation of chromosome organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. go-plus.json regulation of chromosome organisation|regulation of chromosome organization and biogenesis http://purl.obolibrary.org/obo/GO_0033044 GO:0033043 biolink:BiologicalProcess regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. go-plus.json regulation of organelle organization and biogenesis|regulation of organelle organisation http://purl.obolibrary.org/obo/GO_0033043 goslim_yeast GO:0008099 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008099 GO:0008098 biolink:MolecularActivity 5S rRNA primary transcript binding Binding to an unprocessed 5S ribosomal RNA transcript. go-plus.json http://purl.obolibrary.org/obo/GO_0008098 GO:0033031 biolink:BiologicalProcess positive regulation of neutrophil apoptotic process Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process. go-plus.json activation of neutrophil apoptosis|up-regulation of neutrophil apoptosis|positive regulation of neutrophil apoptosis|up regulation of neutrophil apoptosis|upregulation of neutrophil apoptosis|stimulation of neutrophil apoptosis http://purl.obolibrary.org/obo/GO_0033031 GO:0033030 biolink:BiologicalProcess negative regulation of neutrophil apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process. go-plus.json negative regulation of neutrophil apoptosis|down-regulation of neutrophil apoptosis|downregulation of neutrophil apoptosis|down regulation of neutrophil apoptosis|inhibition of neutrophil apoptosis http://purl.obolibrary.org/obo/GO_0033030 GO:0033039 biolink:MolecularActivity salty taste receptor activity Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste. go-plus.json http://purl.obolibrary.org/obo/GO_0033039 GO:0033038 biolink:MolecularActivity bitter taste receptor activity Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste. go-plus.json http://purl.obolibrary.org/obo/GO_0033038 GO:0033037 biolink:BiologicalProcess polysaccharide localization Any process in which a polysaccharide is transported to, or maintained in, a specific location. go-plus.json polysaccharide localisation http://purl.obolibrary.org/obo/GO_0033037 GO:0033036 biolink:BiologicalProcess macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location. go-plus.json macromolecule localisation http://purl.obolibrary.org/obo/GO_0033036 goslim_flybase_ribbon GO:0033035 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033035 GO:0033034 biolink:BiologicalProcess positive regulation of myeloid cell apoptotic process Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. go-plus.json stimulation of myeloid cell apoptosis|up-regulation of myeloid cell apoptosis|activation of myeloid cell apoptosis|positive regulation of myeloid cell apoptosis|up regulation of myeloid cell apoptosis|upregulation of myeloid cell apoptosis http://purl.obolibrary.org/obo/GO_0033034 GO:0033033 biolink:BiologicalProcess negative regulation of myeloid cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. go-plus.json negative regulation of myeloid cell apoptosis|down-regulation of myeloid cell apoptosis|downregulation of myeloid cell apoptosis|down regulation of myeloid cell apoptosis|inhibition of myeloid cell apoptosis http://purl.obolibrary.org/obo/GO_0033033 GO:0033032 biolink:BiologicalProcess regulation of myeloid cell apoptotic process Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. go-plus.json regulation of myeloid cell apoptosis http://purl.obolibrary.org/obo/GO_0033032 GO:0033029 biolink:BiologicalProcess regulation of neutrophil apoptotic process Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process. go-plus.json regulation of neutrophil apoptosis http://purl.obolibrary.org/obo/GO_0033029 GO:0008069 biolink:BiologicalProcess dorsal/ventral axis specification, ovarian follicular epithelium Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster. go-plus.json dorsal/ventral axis determination, follicular epithelium|dorsoventral axis specification, ovarian follicular epithelium|dorsal/ventral axis determination, ovarian follicular epithelium|dorsal-ventral axis specification, ovarian follicular epithelium http://purl.obolibrary.org/obo/GO_0008069 GO:0008068 biolink:MolecularActivity extracellularly glutamate-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. go-plus.json extracellular-glutamate-gated chloride channel activity http://purl.obolibrary.org/obo/GO_0008068 GO:0008067 biolink:MolecularActivity obsolete metabotropic glutamate, GABA-B-like receptor activity OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor. go-plus.json class C G protein coupled receptor|metabotropic glutamate, GABA-B-like receptor activity|class C orphan receptor activity|class C G-protein coupled receptor|class C GPCR http://purl.obolibrary.org/obo/GO_0008067 GO:0008066 biolink:MolecularActivity glutamate receptor activity Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0008066 GO:0008065 biolink:BiologicalProcess establishment of blood-nerve barrier The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier. go-plus.json establishment of blood/nerve barrier http://purl.obolibrary.org/obo/GO_0008065 GO:0008075 biolink:MolecularActivity obsolete receptor guanylate cyclase activity OBSOLETE. Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. go-plus.json receptor guanylate cyclase activity http://purl.obolibrary.org/obo/GO_0008075 GO:0033020 biolink:BiologicalProcess cyclopentanol metabolic process The chemical reactions and pathways involving cyclopentanol. go-plus.json cyclopentanol metabolism http://purl.obolibrary.org/obo/GO_0033020 GO:0008074 biolink:CellularComponent guanylate cyclase complex, soluble Complex that possesses guanylate cyclase activity and is not bound to a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0008074 GO:0008073 biolink:MolecularActivity ornithine decarboxylase inhibitor activity Binds to and stops, prevents or reduces the activity of ornithine decarboxylase. go-plus.json http://purl.obolibrary.org/obo/GO_0008073 GO:0008072 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008072 GO:0008071 biolink:BiologicalProcess maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster. go-plus.json maternal determination of dorsal/ventral axis, follicular epithelium, soma encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, soma encoded|maternal determination of dorsal-ventral axis, ovarian follicular epithelium, soma encoded http://purl.obolibrary.org/obo/GO_0008071 GO:0008070 biolink:BiologicalProcess maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line. go-plus.json maternal determination of dorsal-ventral axis, ovarian follicular epithelium, germ-line encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, germ-line encoded http://purl.obolibrary.org/obo/GO_0008070 GO:0033028 biolink:BiologicalProcess myeloid cell apoptotic process Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. go-plus.json apoptosis of myeloid cells|myeloid cell apoptosis http://purl.obolibrary.org/obo/GO_0033028 GO:0033027 biolink:BiologicalProcess positive regulation of mast cell apoptotic process Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process. go-plus.json up-regulation of mast cell apoptosis|upregulation of mast cell apoptosis|positive regulation of mast cell apoptosis|up regulation of mast cell apoptosis|activation of mast cell apoptosis|stimulation of mast cell apoptosis http://purl.obolibrary.org/obo/GO_0033027 GO:0033026 biolink:BiologicalProcess negative regulation of mast cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process. go-plus.json inhibition of mast cell apoptosis|down regulation of mast cell apoptosis|downregulation of mast cell apoptosis|negative regulation of mast cell apoptosis|down-regulation of mast cell apoptosis http://purl.obolibrary.org/obo/GO_0033026 GO:0033025 biolink:BiologicalProcess regulation of mast cell apoptotic process Any process that modulates the frequency, rate, or extent of mast cell apoptotic process. go-plus.json regulation of mast cell apoptosis http://purl.obolibrary.org/obo/GO_0033025 GO:0033024 biolink:BiologicalProcess mast cell apoptotic process Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. go-plus.json mast cell apoptosis|apoptosis of mast cells http://purl.obolibrary.org/obo/GO_0033024 GO:0033023 biolink:BiologicalProcess mast cell homeostasis The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0033023 GO:0033022 biolink:BiologicalProcess cyclopentanol catabolic process The chemical reactions and pathways resulting in the breakdown of cyclopentanol. go-plus.json cyclopentanol breakdown|cyclopentanol degradation|cyclopentanol catabolism http://purl.obolibrary.org/obo/GO_0033022 GO:0033021 biolink:BiologicalProcess cyclopentanol biosynthetic process The chemical reactions and pathways resulting in the formation of cyclopentanol. go-plus.json cyclopentanol biosynthesis|cyclopentanol anabolism|cyclopentanol synthesis|cyclopentanol formation http://purl.obolibrary.org/obo/GO_0033021 GO:0033019 biolink:MolecularActivity 5-hydroxyvalerate dehydrogenase activity Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH. go-plus.json http://purl.obolibrary.org/obo/GO_0033019 GO:0033018 biolink:CellularComponent sarcoplasmic reticulum lumen The volume enclosed by the membranes of the sarcoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0033018 GO:0008079 biolink:MolecularActivity translation termination factor activity Functions in the termination of translation. go-plus.json http://purl.obolibrary.org/obo/GO_0008079 GO:0008078 biolink:BiologicalProcess mesodermal cell migration The orderly movement of mesodermal cells from one site to another. go-plus.json mesoderm cell migration http://purl.obolibrary.org/obo/GO_0008078 GO:0008077 biolink:MolecularActivity obsolete Hsp70/Hsp90 organizing protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json Hsp70/Hsp90 organizing protein activity|Hsp70/Hsp90 organising protein activity http://purl.obolibrary.org/obo/GO_0008077 GO:0008076 biolink:CellularComponent voltage-gated potassium channel complex A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. NIF_Subcellular:sao371494298 go-plus.json voltage-dependent potassium channel complex|voltage-sensitive potassium channel complex|voltage gated potassium channel complex http://purl.obolibrary.org/obo/GO_0008076 GO:0008086 biolink:MolecularActivity light-activated voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json light-activated voltage-dependent calcium channel activity|light-activated voltage gated calcium channel activity http://purl.obolibrary.org/obo/GO_0008086 GO:0008085 biolink:BiologicalProcess obsolete phototransduction, visible light, light adaptation OBSOLETE. (Was not defined before being made obsolete). go-plus.json phototransduction, visible light, light adaptation http://purl.obolibrary.org/obo/GO_0008085 GO:0008084 biolink:MolecularActivity imaginal disc growth factor receptor binding Binding to an imaginal disc growth factor receptor. go-plus.json imaginal disc growth factor http://purl.obolibrary.org/obo/GO_0008084 GO:0008083 biolink:MolecularActivity growth factor activity The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0008083 goslim_chembl GO:0008081 biolink:MolecularActivity phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group. EC:3.1.4.-|Reactome:R-HSA-5693578 go-plus.json phosphodiesterase http://purl.obolibrary.org/obo/GO_0008081 goslim_chembl GO:0008080 biolink:MolecularActivity N-acetyltransferase activity Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. Reactome:R-HSA-6790987|Reactome:R-HSA-2468039|Reactome:R-HSA-9636560|Reactome:R-HSA-2473152 go-plus.json http://purl.obolibrary.org/obo/GO_0008080 GO:0033017 biolink:CellularComponent sarcoplasmic reticulum membrane The lipid bilayer surrounding the sarcoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0033017 GO:0033016 biolink:CellularComponent rhoptry membrane The lipid bilayer surrounding a rhoptry. go-plus.json http://purl.obolibrary.org/obo/GO_0033016 GO:0033015 biolink:BiologicalProcess tetrapyrrole catabolic process The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. go-plus.json tetrapyrrole catabolism|tetrapyrrole degradation|tetrapyrrole breakdown http://purl.obolibrary.org/obo/GO_0033015 GO:0033014 biolink:BiologicalProcess tetrapyrrole biosynthetic process The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. go-plus.json tetrapyrrole anabolism|tetrapyrrole synthesis|tetrapyrrole biosynthesis|tetrapyrrole formation http://purl.obolibrary.org/obo/GO_0033014 GO:0033013 biolink:BiologicalProcess tetrapyrrole metabolic process The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. go-plus.json tetrapyrrole metabolism http://purl.obolibrary.org/obo/GO_0033013 goslim_pombe GO:0033012 biolink:CellularComponent porosome A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles. Wikipedia:Porosome go-plus.json http://purl.obolibrary.org/obo/GO_0033012 GO:0033011 biolink:CellularComponent perinuclear theca A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0033011 GO:0033010 biolink:CellularComponent paranodal junction A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath. go-plus.json paranodal axoglial junction|paranodal septate junction|axoglial septate junction http://purl.obolibrary.org/obo/GO_0033010 GO:0047650 biolink:MolecularActivity alkylglycerone kinase activity Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+). KEGG_REACTION:R03944|EC:2.7.1.84|RHEA:23088|MetaCyc:ALKYLGLYCERONE-KINASE-RXN go-plus.json ATP:O-alkylglycerone phosphotransferase activity|alkyldihydroxyacetone kinase (phosphorylating)|alkyldihydroxyacetone kinase activity http://purl.obolibrary.org/obo/GO_0047650 CHEBI:24522 biolink:ChemicalSubstance heptenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24522 UBERON:0015791 biolink:AnatomicalEntity digit connective tissue A portion of connective tissue that is part of a digit. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015791 UBERON:0015790 biolink:AnatomicalEntity autopod skin A zone of skin that is part of a autopod region. go-plus.json paw skin http://purl.obolibrary.org/obo/UBERON_0015790 CHEBI:24521 biolink:ChemicalSubstance heptenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24521 CHEBI:24523 biolink:ChemicalSubstance heptenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24523 GO:0047658 biolink:MolecularActivity alpha-amino-acid esterase activity Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol. MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN|EC:3.1.1.43|Reactome:R-HSA-6784959|RHEA:17241 go-plus.json alpha-amino acid ester hydrolase activity|alpha-amino-acid-ester aminoacylhydrolase activity|a-amino-acid esterase activity|alpha-amino-acid ester hydrolase activity http://purl.obolibrary.org/obo/GO_0047658 GO:0047657 biolink:MolecularActivity alpha-1,3-glucan synthase activity Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1. MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN|RHEA:19749|EC:2.4.1.183 go-plus.json 1,3-alpha-glucan synthase activity|UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity|a-1,3-glucan synthase activity|1,3-alpha-D-glucan synthase activity|UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047657 GO:0047656 biolink:MolecularActivity alpha,alpha-trehalose phosphorylase activity Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate. MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN|EC:2.4.1.64|RHEA:23512 go-plus.json trehalose phosphorylase|alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity|a,a-trehalose phosphorylase activity http://purl.obolibrary.org/obo/GO_0047656 GO:0047655 biolink:MolecularActivity allyl-alcohol dehydrogenase activity Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH. EC:1.1.1.54|RHEA:12168|KEGG_REACTION:R03572|MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN go-plus.json allyl-alcohol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047655 GO:0047654 biolink:MolecularActivity alliin lyase activity Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate. MetaCyc:ALLIIN-LYASE-RXN|RHEA:20141|EC:4.4.1.4 go-plus.json cysteine sulfoxide lyase activity|L-cysteine sulfoxide lyase activity|alliinase activity|S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)|alkylcysteine sulfoxide lyase activity|cysteine sulphoxide lyase activity|S-alkylcysteine sulfoxide lyase activity|alliin alkyl-sulfenate-lyase activity http://purl.obolibrary.org/obo/GO_0047654 UBERON:0015795 biolink:AnatomicalEntity right lung lobar bronchus epitheium A epithelium that is part of a lobar bronchus of right lung. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015795 GO:0047653 biolink:MolecularActivity allantoin racemase activity Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin. EC:5.1.99.3|RHEA:10804|KEGG_REACTION:R03925|MetaCyc:ALLANTOIN-RACEMASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0047653 UBERON:0015794 biolink:AnatomicalEntity left lung lobar bronchus epithelium A epithelium that is part of a lobar bronchus of left lung. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015794 GO:0047652 biolink:MolecularActivity allantoate deiminase activity Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine. MetaCyc:ALLANTOATE-DEIMINASE-RXN|EC:3.5.3.9|RHEA:27485 go-plus.json allantoate amidinohydrolase (decarboxylating)|allantoate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047652 UBERON:0015796 biolink:AnatomicalEntity liver blood vessel A blood vessel that is part of a liver. go-plus.json hepatic blood vessel http://purl.obolibrary.org/obo/UBERON_0015796 GO:0047651 biolink:MolecularActivity alkylhalidase activity Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+). KEGG_REACTION:R03523|RHEA:13765|MetaCyc:ALKYLHALIDASE-RXN go-plus.json halogenase activity|alkyl-halide halidohydrolase activity|haloalkane halidohydrolase activity http://purl.obolibrary.org/obo/GO_0047651 NCBITaxon:45351 biolink:OrganismalEntity Nematostella vectensis go-plus.json starlet sea anemone http://purl.obolibrary.org/obo/NCBITaxon_45351 NCBITaxon:45350 biolink:OrganismalEntity Nematostella go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_45350 UBERON:0001152 biolink:AnatomicalEntity cystic duct the tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct go-plus.json ductus cysticus http://purl.obolibrary.org/obo/UBERON_0001152 GO:0072619 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072619 GO:0072618 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072618 CHEBI:167637 biolink:ChemicalSubstance mycofactocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_167637 GO:0072617 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072617 GO:0072616 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072616 GO:0047659 biolink:MolecularActivity alpha-santonin 1,2-reductase activity Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+. EC:1.3.1.47|MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN go-plus.json 1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity|a-santonin 1,2-reductase activity http://purl.obolibrary.org/obo/GO_0047659 GO:0072615 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072615 UBERON:0001158 biolink:AnatomicalEntity descending colon The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon. go-plus.json colon descendens http://purl.obolibrary.org/obo/UBERON_0001158 GO:0072614 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072614 GO:0072613 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072613 SO:0000315 biolink:SequenceFeature TSS The first base where RNA polymerase begins to synthesize the RNA transcript. go-plus.json transcription start site|transcription_start_site|INSDC_feature:misc_feature|INSDC_note:transcription_start_site http://purl.obolibrary.org/obo/SO_0000315 SOFA UBERON:0001157 biolink:AnatomicalEntity transverse colon The proximal-distal subdivision of colon that runs transversely across the upper part of the abdomen, from the right to the left colic flexure. Continuous with the descending colon[BTO,modified]. go-plus.json colon transversum http://purl.obolibrary.org/obo/UBERON_0001157 GO:0072612 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072612 GO:0072611 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072611 UBERON:0001159 biolink:AnatomicalEntity sigmoid colon The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity. go-plus.json sigmoid flexure|pelvic colon|colon sigmoideum|sigmoid colon http://purl.obolibrary.org/obo/UBERON_0001159 CHEBI:24527 biolink:ChemicalSubstance herbicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24527 GO:0072610 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072610 UBERON:0001153 biolink:AnatomicalEntity caecum A pouch in the digestive tract that connects the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction. go-plus.json intestinum caecum|cecum|blind intestine|intestinum crassum caecum|caecum|intestinum crassum cecum|blindgut|caeca|ceca http://purl.obolibrary.org/obo/UBERON_0001153 UBERON:0001156 biolink:AnatomicalEntity ascending colon Section of colon which is distal to the cecum and proximal to the transversecolon.[FMA,modified] go-plus.json colon ascendens|spiral colon http://purl.obolibrary.org/obo/UBERON_0001156 UBERON:0001155 biolink:AnatomicalEntity colon A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal. go-plus.json posterior intestine|large bowel|hindgut http://purl.obolibrary.org/obo/UBERON_0001155 GO:0047661 biolink:MolecularActivity amino-acid racemase activity Catalysis of the reaction: an L-amino acid = a D-amino acid. MetaCyc:AMINO-ACID-RACEMASE-RXN|EC:5.1.1.10|RHEA:18317 go-plus.json L-amino acid racemase activity http://purl.obolibrary.org/obo/GO_0047661 CHEBI:24533 biolink:ChemicalSubstance heterodetic cyclic peptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24533 GO:0047660 biolink:MolecularActivity amidinoaspartase activity Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea. MetaCyc:AMIDINOASPARTASE-RXN|RHEA:14849|KEGG_REACTION:R00777|EC:3.5.3.14 go-plus.json N-amidino-L-aspartate amidinohydrolase activity|amidinoaspartic amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0047660 CHEBI:24532 biolink:ChemicalSubstance organic heterocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_24532 CHEBI:24531 biolink:ChemicalSubstance heterocyclic antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_24531 CHEBI:24536 biolink:ChemicalSubstance hexachlorocyclohexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_24536 chebi_ph7_3 OBA:1000115 biolink:OntologyClass axon length The length of a axon. go-plus.json axon length trait|length of axon http://purl.obolibrary.org/obo/OBA_1000115 GO:0047669 biolink:MolecularActivity amylosucrase activity Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1). RHEA:24572|EC:2.4.1.4|MetaCyc:AMYLOSUCRASE-RXN go-plus.json sucrose-glucan glucosyltransferase activity|sucrose-1,4-alpha-glucan glucosyltransferase activity|sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047669 UBERON:0015788 biolink:AnatomicalEntity olfactory apparatus chamber An anatomical chamber that is part of the olfactory apparatus, consisting of cavity walls (nasal epithelium and mucosal layers) and the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015788 GO:0047668 biolink:MolecularActivity amygdalin beta-glucosidase activity Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose. EC:3.2.1.117|RHEA:14177|MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R02985 go-plus.json amygdalin hydrolase activity|amygdalin b-glucosidase activity|amygdalin glucosidase activity|amygdalin beta-D-glucohydrolase activity|amygdalinase|(R)-amygdalin beta-glucosidase activity http://purl.obolibrary.org/obo/GO_0047668 UBERON:0015787 biolink:AnatomicalEntity upper respiratory conduit Any anatomical conduit which is part of the upper respiratory tract go-plus.json respiratory conduit http://purl.obolibrary.org/obo/UBERON_0015787 GO:0047667 biolink:MolecularActivity AMP-thymidine kinase activity Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate. EC:2.7.1.114|MetaCyc:AMP--THYMIDINE-KINASE-RXN|RHEA:14913 go-plus.json adenylic acid:deoxythymidine 5'-phosphotransferase activity|AMP:deoxythymidine 5'-phosphotransferase activity|AMP:thymidine 5'-phosphotransferase activity|thymidine phosphotransferase activity|AMP:deoxythymidine kinase activity|AMP:dThd kinase activity|adenylate-nucleoside phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047667 GO:0047666 biolink:MolecularActivity ammonia kinase activity Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate. KEGG_REACTION:R00141|MetaCyc:AMMONIA-KINASE-RXN|EC:2.7.3.8|RHEA:11024 go-plus.json phosphoramidate-ADP-phosphotransferase activity|ATP:ammonia phosphotransferase activity|phosphoramidate-adenosine diphosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047666 UBERON:0015789 biolink:AnatomicalEntity cranial or facial muscle go-plus.json craniofacial muscle|cranio-facial muscle|cranial/facial muscle|cranial-facial muscle http://purl.obolibrary.org/obo/UBERON_0015789 NCBITaxon:45349 biolink:OrganismalEntity Edwardsiidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_45349 GO:0047665 biolink:MolecularActivity aminolevulinate transaminase activity Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine. KEGG_REACTION:R02271|RHEA:12480|MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN|EC:2.6.1.43 go-plus.json L-alanine:4,5-dioxovaleric acid transaminase activity|alanine:4,5-dioxovalerate aminotransferase activity|5-aminolevulinate:pyruvate aminotransferase activity|L-alanine:dioxovalerate transaminase activity|5-aminolevulinic acid transaminase activity|alanine-dioxovalerate aminotransferase activity|aminolevulinic acid transaminase activity|aminolevulinate aminotransferase activity|4,5-dioxovaleric acid transaminase activity|4,5-dioxovalerate aminotransferase activity|dioxovalerate transaminase activity|L-alanine-4,5-dioxovalerate aminotransferase activity|gamma,delta-dioxovaleric acid transaminase activity|gamma,delta-dioxovalerate aminotransferase activity|4,5-dioxovaleric transaminase activity|alanine-gamma,delta-dioxovalerate aminotransferase activity|DOVA transaminase activity|4,5-dioxovaleric acid aminotransferase activity http://purl.obolibrary.org/obo/GO_0047665 GO:0047664 biolink:MolecularActivity aminoimidazolase activity Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH(3). MetaCyc:R13-RXN|RHEA:22348|EC:3.5.4.8 go-plus.json 4-aminoimidazole aminohydrolase activity|4-aminoimidazole hydrolase activity http://purl.obolibrary.org/obo/GO_0047664 UBERON:0015783 biolink:AnatomicalEntity smooth muscle layer in fatty layer of subcutaneous tissue A smooth muscle tissue that is part of a hypodermis. go-plus.json muscle layer in fatty layer of subcutaneous tissue|stratum musculosum panniculi adiposi telae subcutaneae http://purl.obolibrary.org/obo/UBERON_0015783 GO:0047663 biolink:MolecularActivity aminoglycoside 6'-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring. MetaCyc:AMINOGLYCOSIDE-N6-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R01889|RHEA:16449|EC:2.3.1.82 go-plus.json 6'-aminoglycoside-N-acetyltransferase activity|aminoglycoside N6'-acetyltransferase activity|AAC(6') activity|kanamycin 6'-N-acetyltransferase activity|aminoglycoside-6-N-acetyltransferase activity|aminoglycoside-6'-acetyltransferase activity|acetyl-CoA:kanamycin-B N6'-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047663 GO:0047662 biolink:MolecularActivity aminobenzoate decarboxylase activity Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2. MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN|EC:4.1.1.24|RHEA:24200 go-plus.json aminobenzoate carboxy-lyase activity|aminobenzoate carboxy-lyase (aniline-forming) http://purl.obolibrary.org/obo/GO_0047662 UBERON:0001141 biolink:AnatomicalEntity right renal vein A renal vein that drains the right kidney go-plus.json http://purl.obolibrary.org/obo/UBERON_0001141 GO:0072609 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072609 UBERON:0001140 biolink:AnatomicalEntity renal vein Either of the pair of major vessels which arise from the renal hilus and return blood from the kidneys, suprarenal gland and the ureter to the inferior vena cava. go-plus.json vein of kidney|kidney vein|renal venous tree|venae renales http://purl.obolibrary.org/obo/UBERON_0001140 GO:0072608 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072608 GO:0072607 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072607 GO:0072606 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072606 GO:0072605 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072605 GO:0072604 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072604 GO:0072603 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072603 SO:0000305 biolink:SequenceFeature modified_DNA_base A modified nucleotide, i.e. a nucleotide other than A, T, C. G. go-plus.json modified base site|INSDC_feature:modified_base http://purl.obolibrary.org/obo/SO_0000305 SOFA UBERON:0001146 biolink:AnatomicalEntity suprarenal vein A vein that drains the adrenal gland. go-plus.json adrenal vein http://purl.obolibrary.org/obo/UBERON_0001146 GO:0072602 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072602 GO:0072601 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072601 GO:0072600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072600 UBERON:0001143 biolink:AnatomicalEntity hepatic vein Vein that carries blood away from the liver[ZFA]. go-plus.json liver vein|vein of liver|venae hepaticae|vena hepatica|hepatic veins http://purl.obolibrary.org/obo/UBERON_0001143 UBERON:0001142 biolink:AnatomicalEntity left renal vein A renal vein that drains the left kidney go-plus.json http://purl.obolibrary.org/obo/UBERON_0001142 UBERON:0001145 biolink:AnatomicalEntity ovarian vein A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries. go-plus.json female reproductive system gonad vein|vena ovarica sinistra|vein of female reproductive system gonad|vein of ovary|gonad of female reproductive system vein|vein of gonada of female reproductive system|vein of female reproductive system gonada|female reproductive system gonada vein|vena ovarica dextra|vein of gonad of female reproductive system|gonada of female reproductive system vein|ovary vein http://purl.obolibrary.org/obo/UBERON_0001145 UBERON:0001144 biolink:AnatomicalEntity testicular vein A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis. go-plus.json venae spermaticae|testicle vein|vena testicularis dextra|vena tesicularis|spermatic vein|testicular venous tree|vein of testicle|vena testicularis sinistra|male gonadal vein http://purl.obolibrary.org/obo/UBERON_0001144 GO:0047672 biolink:MolecularActivity anthranilate N-benzoyltransferase activity Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA. RHEA:21600|KEGG_REACTION:R02453|EC:2.3.1.144|MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN go-plus.json benzoyl-CoA:anthranilate N-benzoyltransferase http://purl.obolibrary.org/obo/GO_0047672 CHEBI:24500 biolink:ChemicalSubstance heparan go-plus.json http://purl.obolibrary.org/obo/CHEBI_24500 GO:0047671 biolink:MolecularActivity anthranilate adenylyltransferase activity Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+). KEGG_REACTION:R00979|RHEA:22412|MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.55 go-plus.json ATP:anthranilate N-adenylyltransferase activity|ATP:anthranilate adenylyltransferase activity|anthranilic acid adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0047671 GO:0047670 biolink:MolecularActivity anhydrotetracycline monooxygenase activity Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+). RHEA:11976|KEGG_REACTION:R04060|EC:1.14.13.38|MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN go-plus.json anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)|ATC oxygenase activity|anhydrotetracycline oxygenase activity http://purl.obolibrary.org/obo/GO_0047670 GO:0047679 biolink:MolecularActivity arginine racemase activity Catalysis of the reaction: L-arginine = D-arginine. EC:5.1.1.9|MetaCyc:ARGININE-RACEMASE-RXN|RHEA:18069 go-plus.json http://purl.obolibrary.org/obo/GO_0047679 GO:0047678 biolink:MolecularActivity arginine 2-monooxygenase activity Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O. EC:1.13.12.1|KEGG_REACTION:R00559|RHEA:10548|MetaCyc:ARGININE-2-MONOOXYGENASE-RXN go-plus.json arginine monooxygenase activity|arginine oxygenase (decarboxylating) activity|arginine decarboxy-oxidase activity|L-arginine:oxygen 2-oxidoreductase (decarboxylating) http://purl.obolibrary.org/obo/GO_0047678 GO:0047677 biolink:MolecularActivity arachidonate 8(R)-lipoxygenase activity Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. EC:1.13.11.40|RHEA:14985|KEGG_REACTION:R01594|MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN go-plus.json arachidonate:oxygen 8-oxidoreductase activity|arachidonate 8-lipoxygenase activity|8(R)-lipoxygenase activity|8-lipoxygenase activity http://purl.obolibrary.org/obo/GO_0047677 GO:0047676 biolink:MolecularActivity arachidonate-CoA ligase activity Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+). MetaCyc:ARACHIDONATE--COA-LIGASE-RXN|EC:6.2.1.15|KEGG_REACTION:R01598|RHEA:19713 go-plus.json arachidonate:CoA ligase (AMP-forming)|arachidonoyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0047676 GO:0047675 biolink:MolecularActivity arabinonate dehydratase activity Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O. RHEA:21836|EC:4.2.1.5|KEGG_REACTION:R03032|MetaCyc:ARABINONATE-DEHYDRATASE-RXN go-plus.json D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)|D-arabinonate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047675 GO:0047674 biolink:MolecularActivity apiose 1-reductase activity Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH. KEGG_REACTION:R03577|MetaCyc:APIOSE-1-REDUCTASE-RXN|RHEA:15301|EC:1.1.1.114 go-plus.json D-apiose reductase activity|D-apiitol:NAD+ 1-oxidoreductase activity|D-apiitol reductase activity http://purl.obolibrary.org/obo/GO_0047674 GO:0047673 biolink:MolecularActivity anthranilate N-malonyltransferase activity Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA. KEGG_REACTION:R00989|RHEA:17557|EC:2.3.1.113|MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN go-plus.json malonyl-CoA:anthranilate N-malonyltransferase activity http://purl.obolibrary.org/obo/GO_0047673 UBERON:0001130 biolink:AnatomicalEntity vertebral column Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]. go-plus.json vertebral region|columna vertebralis|spine|dorsal spine|backbone|vertebral column skeleton|spinal column http://purl.obolibrary.org/obo/UBERON_0001130 GO:0072639 biolink:BiologicalProcess interleukin-33 production The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json NF-HEV production|IL-33 production|C9orf26 production|interleukin-33 secretion|IL1F11 production|interleukin-33 biosynthetic process|IL33 production http://purl.obolibrary.org/obo/GO_0072639 gocheck_do_not_annotate GO:0072638 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072638 GO:0072637 biolink:BiologicalProcess interleukin-32 production The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TAIF production|IL-32 production|interleukin-32 secretion|NK4 production|interleukin-32 biosynthetic process|IL32 production http://purl.obolibrary.org/obo/GO_0072637 gocheck_do_not_annotate GO:0072636 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072636 UBERON:0001136 biolink:AnatomicalEntity mesothelium Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). go-plus.json http://purl.obolibrary.org/obo/UBERON_0001136 UBERON:0001135 biolink:AnatomicalEntity smooth muscle tissue Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]. go-plus.json smooth muscle|visceral muscle|involuntary muscle|textus muscularis nonstriatus|visceral muscle tissue|non-striated muscle|textus muscularis levis; textus muscularis nonstriatus http://purl.obolibrary.org/obo/UBERON_0001135 GO:0072635 biolink:BiologicalProcess interleukin-31 production The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-31 production|interleukin-31 secretion http://purl.obolibrary.org/obo/GO_0072635 gocheck_do_not_annotate UBERON:0001138 biolink:AnatomicalEntity superior mesenteric vein In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. go-plus.json vena mesenterica superior|upper mesenteric vein http://purl.obolibrary.org/obo/UBERON_0001138 GO:0072634 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072634 GO:0072633 biolink:BiologicalProcess interleukin-30 production The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-30 production|interleukin-30 complex production|interleukin-30 secretion http://purl.obolibrary.org/obo/GO_0072633 gocheck_do_not_annotate UBERON:0001137 biolink:AnatomicalEntity dorsum A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.. go-plus.json back of body proper|dorsal part of organism|back http://purl.obolibrary.org/obo/UBERON_0001137 CHEBI:24505 biolink:ChemicalSubstance heparins go-plus.json http://purl.obolibrary.org/obo/CHEBI_24505 UBERON:0001132 biolink:AnatomicalEntity parathyroid gland The parathyroid gland is an endocrine gland for secretion of parathyroid hormone, usually found as a pair, embedded in the connective tissue capsule on the posterior surface of the thyroid gland. Parathyroid regulates calcium and phosphorous metabolism. go-plus.json epithelial body|parathyroid|parathyroid secreting cell http://purl.obolibrary.org/obo/UBERON_0001132 GO:0072632 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072632 GO:0072631 biolink:BiologicalProcess interleukin-29 production The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-29 secretion|IL29 production|IL-29 production|interferon lambda 1 production http://purl.obolibrary.org/obo/GO_0072631 gocheck_do_not_annotate UBERON:0001131 biolink:AnatomicalEntity vertebral foramen A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch. go-plus.json vertebra neural canal|foramen vertebrale http://purl.obolibrary.org/obo/UBERON_0001131 SO:0000336 biolink:SequenceFeature pseudogene A sequence that closely resembles a known functional gene, at another locus within a genome, that is non-functional as a consequence of (usually several) mutations that prevent either its transcription or translation (or both). In general, pseudogenes result from either reverse transcription of a transcript of their "normal" paralog (SO:0000043) (in which case the pseudogene typically lacks introns and includes a poly(A) tail) or from recombination (SO:0000044) (in which case the pseudogene is typically a tandem duplication of its "normal" paralog). http://en.wikipedia.org/wiki/Pseudogene go-plus.json INSDC_qualifier:unknown|INSDC_feature:gene|INSDC_qualifier:pseudo http://purl.obolibrary.org/obo/SO_0000336 Alliance_of_Genome_Resources|SOFA GO:0072630 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072630 UBERON:0001134 biolink:AnatomicalEntity skeletal muscle tissue Muscle tissue that consists primarily of skeletal muscle fibers. go-plus.json skeletal muscle system|somatic muscle|skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 UBERON:0001133 biolink:AnatomicalEntity cardiac muscle tissue Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]. go-plus.json myocardium muscle tissue|muscle of heart muscle tissue|heart muscle muscle tissue|textus muscularis of cardiac muscle|cardiac musculature|heart myocardium muscle tissue|textus muscularis of myocardium|cardiac muscle|cardiac muscle textus muscularis|textus muscularis of heart muscle|muscle tissue of cardiac muscle|textus muscularis of heart myocardium|muscle tissue of muscle of heart|myocardium textus muscularis|muscle of heart textus muscularis|muscle tissue of myocardium|cardiac muscle muscle tissue|heart muscle textus muscularis|muscle tissue of heart muscle|heart myocardium textus muscularis|muscle tissue of heart myocardium|textus muscularis of muscle of heart http://purl.obolibrary.org/obo/UBERON_0001133 SO:0000330 biolink:SequenceFeature conserved_region Region of sequence similarity by descent from a common ancestor. http://en.wikipedia.org/wiki/Conserved_region go-plus.json INSDC_note:conserved_region|INSDC_feature:misc_feature|conserved region http://purl.obolibrary.org/obo/SO_0000330 SOFA GO:0047683 biolink:MolecularActivity aryl-aldehyde dehydrogenase (NADP+) activity Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP. MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN|EC:1.2.1.30|RHEA:19229 go-plus.json aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)|aromatic acid reductase activity http://purl.obolibrary.org/obo/GO_0047683 GO:0047682 biolink:MolecularActivity aryl-alcohol oxidase activity Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2. MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN|EC:1.1.3.7|RHEA:17541 go-plus.json arom. alcohol oxidase activity|aryl-alcohol:oxygen oxidoreductase activity|aryl alcohol oxidase activity|veratryl alcohol oxidase activity http://purl.obolibrary.org/obo/GO_0047682 GO:0047681 biolink:MolecularActivity aryl-alcohol dehydrogenase (NADP+) activity Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH. MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.91|RHEA:17761 go-plus.json aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)|NADPH-linked benzaldehyde reductase activity|aryl-alcohol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047681 GO:0047680 biolink:MolecularActivity aryl-acylamidase activity Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+). MetaCyc:ARYL-ACYLAMIDASE-RXN|EC:3.5.1.13|KEGG_REACTION:R01862|RHEA:20297 go-plus.json AAA-2|AAA-1|pseudocholinesterase (associated with arylacylamidase)|aryl-acylamide amidohydrolase activity|brain acetylcholinesterase (is associated with AAA-2) http://purl.obolibrary.org/obo/GO_0047680 UBERON:0001118 biolink:AnatomicalEntity lobe of thyroid gland A lobe of tissue that is part of a thyroid gland. go-plus.json thyroid lobe|lobuli glandulae thyroideae|lobus glandulae thyroideae|thyroid gland lobe|lobus (glandula thyroidea) http://purl.obolibrary.org/obo/UBERON_0001118 UBERON:0001119 biolink:AnatomicalEntity right lobe of thyroid gland A lobe of thyroid gland that is in the right side of a thyroid gland. go-plus.json lobus dexter (glandula thyroidea)|thyroid gland right lobe|right thyroid lobe http://purl.obolibrary.org/obo/UBERON_0001119 UBERON:0015766 biolink:AnatomicalEntity epithelium of duct of salivary gland A epithelium that is part of a duct of salivary gland. go-plus.json salivary duct epithelium|salivary ductal epithelium|epithelium of salivary duct http://purl.obolibrary.org/obo/UBERON_0015766 GO:0047689 biolink:MolecularActivity aspartate racemase activity Catalysis of the reaction: L-aspartate = D-aspartate. KEGG_REACTION:R00491|MetaCyc:ASPARTATE-RACEMASE-RXN|EC:5.1.1.13|RHEA:14973 go-plus.json D-aspartate racemase activity http://purl.obolibrary.org/obo/GO_0047689 GO:0047688 biolink:MolecularActivity aspartate 4-decarboxylase activity Catalysis of the reaction: L-aspartate = L-alanine + CO2. MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN|EC:4.1.1.12|RHEA:12621 go-plus.json L-aspartate 4-carboxy-lyase (L-alanine-forming)|aspartate omega-decarboxylase activity|L-cysteine sulfinate acid desulfinase activity|aspartic beta-decarboxylase activity|L-aspartate 4-carboxy-lyase activity|desulfinase activity|cysteine sulfinic desulfinase activity|aspartic omega-decarboxylase activity|aminomalonic decarboxylase activity|aspartate beta-decarboxylase activity|L-aspartate beta-decarboxylase activity http://purl.obolibrary.org/obo/GO_0047688 GO:0047687 biolink:MolecularActivity obsolete ascorbate 2,3-dioxygenase activity OBSOLETE. Catalysis of the reaction: L-ascorbate + H(2)O + O(2) = L-threonate + 2 H(+) + oxalate. MetaCyc:ASCORBATE-23-DIOXYGENASE-RXN|KEGG_REACTION:R00646|RHEA:21784 go-plus.json ascorbate:oxygen 2,3-oxidoreductase (bond-cleaving)|AAoxygenase activity|ascorbate 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0047687 GO:0047686 biolink:MolecularActivity arylsulfate sulfotransferase activity Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate. MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN|EC:2.8.2.22|RHEA:51072 go-plus.json arylsulfate:phenol sulfotransferase activity|arylsulphate sulphotransferase activity|arylsulfate-phenol sulfotransferase activity|arylsulfotransferase|ASST http://purl.obolibrary.org/obo/GO_0047686 GO:0047685 biolink:MolecularActivity amine sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate. MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN|RHEA:24136|EC:2.8.2.3 go-plus.json amine sulphotransferase activity|3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity|amine N-sulfotransferase activity|arylamine sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047685 PR:000024990 biolink:Protein type II interferon A protein that binds to a specific cell surface receptor complex known as the IFN-gamma receptor (IFNGR), a complex of two IFNGR1 and two IFNGR2 chains. go-plus.json interferon type II|interferon gamma|IFN type II http://purl.obolibrary.org/obo/PR_000024990 GO:0047684 biolink:MolecularActivity arylamine glucosyltransferase activity Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine. MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.71 go-plus.json UDP-glucose:arylamine N-D-glucosyltransferase activity|UDP glucose-arylamine glucosyltransferase activity|uridine diphosphoglucose-arylamine glucosyltransferase activity|UDPglucose:arylamine N-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047684 GO:0072629 biolink:BiologicalProcess interleukin-28B production The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-28B production|IL28B production|interferon lambda 3 production|interleukin-28B secretion http://purl.obolibrary.org/obo/GO_0072629 gocheck_do_not_annotate GO:0072628 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072628 GO:0072627 biolink:BiologicalProcess interleukin-28A production The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL28A production|interferon lambda 2 production|interleukin-28A secretion|IL-28A production http://purl.obolibrary.org/obo/GO_0072627 gocheck_do_not_annotate GO:0072626 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072626 UBERON:0001125 biolink:AnatomicalEntity serratus ventralis The serratus ventralis is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted]. go-plus.json serratus anterior|Boxer's muscle|serratus lateralis|musculus serratus anterior|serratus ventralis muscle|serratus anterior muscle http://purl.obolibrary.org/obo/UBERON_0001125 GO:0072625 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072625 GO:0072624 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072624 GO:0072623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072623 GO:0072622 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072622 GO:0072621 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072621 UBERON:0001120 biolink:AnatomicalEntity left lobe of thyroid gland A lobe of thyroid gland that is in the left side of a thyroid gland. go-plus.json thyroid gland left lobe|lobus sinister (glandula thyroidea)|left thyroid lobe http://purl.obolibrary.org/obo/UBERON_0001120 GO:0072620 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072620 GO:0072650 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072650 GO:0047694 biolink:MolecularActivity barbiturase activity Catalysis of the reaction: barbiturate + H2O = malonate + urea. RHEA:18653|MetaCyc:BARBITURASE-RXN|EC:3.5.2.1 go-plus.json barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming) http://purl.obolibrary.org/obo/GO_0047694 GO:0047693 biolink:MolecularActivity ATP diphosphatase activity Catalysis of the reaction: ATP + H2O = AMP + diphosphate. EC:3.6.1.8|RHEA:14245|MetaCyc:ATP-PYROPHOSPHATASE-RXN go-plus.json ATP pyrophosphatase activity|ATP diphosphohydrolase (diphosphate-forming)|adenosine triphosphate pyrophosphatase activity|ATP diphosphohydrolase http://purl.obolibrary.org/obo/GO_0047693 GO:0047692 biolink:MolecularActivity ATP deaminase activity Catalysis of the reaction: ATP + H2O = ITP + NH3. EC:3.5.4.18|RHEA:13037|MetaCyc:ATP-DEAMINASE-RXN go-plus.json ATP aminohydrolase activity|adenosine triphosphate deaminase activity http://purl.obolibrary.org/obo/GO_0047692 GO:0047691 biolink:MolecularActivity aspulvinone dimethylallyltransferase activity Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate. EC:2.5.1.35|KEGG_REACTION:R03799|RHEA:13809|MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN go-plus.json dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity|dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity http://purl.obolibrary.org/obo/GO_0047691 GO:0047690 biolink:MolecularActivity aspartyltransferase activity Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+). KEGG_REACTION:R01485|EC:2.3.2.7|RHEA:11252|MetaCyc:ASPARTYLTRANSFERASE-RXN go-plus.json L-asparagine:hydroxylamine gamma-aspartyltransferase activity|beta-aspartyl transferase activity|aspartotransferase activity http://purl.obolibrary.org/obo/GO_0047690 GO:0047699 biolink:MolecularActivity beta-diketone hydrolase activity Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one. EC:3.7.1.7|KEGG_REACTION:R03781|MetaCyc:BETA-DIKETONE-HYDROLASE-RXN|RHEA:11908 go-plus.json oxidized PVA hydrolase activity|nonane-4,6-dione acylhydrolase activity|b-diketone hydrolase activity http://purl.obolibrary.org/obo/GO_0047699 GO:0047698 biolink:MolecularActivity beta-alanyl-CoA ammonia-lyase activity Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3. RHEA:12416|EC:4.3.1.6|MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN go-plus.json beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)|b-alanyl-CoA ammonia-lyase activity|beta-alanyl coenzyme A ammonia-lyase activity http://purl.obolibrary.org/obo/GO_0047698 GO:0047697 biolink:MolecularActivity beta-alanopine dehydrogenase activity Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate. EC:1.5.1.26|RHEA:21684|MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN|KEGG_REACTION:R00906 go-plus.json b-alanopine dehydrogenase activity|N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming) http://purl.obolibrary.org/obo/GO_0047697 GO:0047696 biolink:MolecularActivity beta-adrenergic receptor kinase activity Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor. RHEA:19429|EC:2.7.11.15|Reactome:R-HSA-8866268|Reactome:R-HSA-8851797 go-plus.json ATP:beta-adrenergic-receptor phosphotransferase activity|beta-adrenoceptor kinase activity|beta-adrenergic receptor-specific kinase activity|betaARK1|adrenergic receptor kinase activity|beta-receptor kinase activity|beta-adrenoceptor kinase 1 activity|beta-adrenoceptor kinase 2 activity|[b-adrenergic-receptor] kinase activity|beta-ARK|beta-adrenergic-receptor kinase activity|beta-AR kinase activity|ADRBK1|BARK1|beta2ARK|GRK3|GRK2|beta-adrenergic-receptor kinase (phosphorylating) activity|beta-ARK 2|STK15|beta-ARK 1 http://purl.obolibrary.org/obo/GO_0047696 GO:0047695 biolink:MolecularActivity benzoin aldolase activity Catalysis of the reaction: benzoin = 2 benzaldehyde. MetaCyc:BENZOIN-ALDOLASE-RXN|KEGG_REACTION:R00027|RHEA:21460|EC:4.1.2.38 go-plus.json 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity|diphenylethanone benzaldehyde-lyase activity|benzaldehyde lyase activity http://purl.obolibrary.org/obo/GO_0047695 UBERON:0001194 biolink:AnatomicalEntity splenic artery An artery that supplies the spleen. go-plus.json lienal artery|arteria lienalis|arteria splenica http://purl.obolibrary.org/obo/UBERON_0001194 UBERON:0001193 biolink:AnatomicalEntity hepatic artery An artery that supplies the liver. go-plus.json arteria hepatica|arteria hepatica propria http://purl.obolibrary.org/obo/UBERON_0001193 UBERON:0001190 biolink:AnatomicalEntity ovarian artery An artery that supplies an ovary. go-plus.json arteria ovarica|ovarian arterial tree http://purl.obolibrary.org/obo/UBERON_0001190 GO:0072659 biolink:BiologicalProcess protein localization to plasma membrane A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. go-plus.json protein localization in plasma membrane|protein targeting to plasma membrane|protein localisation in plasma membrane|protein-plasma membrane targeting http://purl.obolibrary.org/obo/GO_0072659 goslim_pombe UBERON:0001191 biolink:AnatomicalEntity common iliac artery The common iliac arteries are two large arteries, about 4cm long in adults but more than a centimetre in diameter, that originate from the aortic bifurcation. The arteries run inferolaterally, along the medial border of the psoas muscles to the pelvic brim, where they bifurcate into the external iliac artery and internal iliac artery. The common iliac artery, and all of its branches, exist as paired structures (that is to say, there is one on the left side and one on the right). The distribution of the common iliac artery is basically the pelvis and lower limb on the corresponding side. Both common iliac arteries are accompanied along their course by common iliac veins. [WP,unvetted]. go-plus.json common iliac arterial tree|arteria iliaca communis http://purl.obolibrary.org/obo/UBERON_0001191 GO:0072658 biolink:BiologicalProcess maintenance of protein location in membrane Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0072658 GO:0072657 biolink:BiologicalProcess protein localization to membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane. go-plus.json protein localisation in membrane|protein localization in membrane http://purl.obolibrary.org/obo/GO_0072657 GO:0072656 biolink:BiologicalProcess maintenance of protein location in mitochondrion Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0072656 GO:0072655 biolink:BiologicalProcess establishment of protein localization to mitochondrion The directed movement of a protein to the mitochondrion or a part of the mitochondrion. go-plus.json establishment of protein localisation to mitochondrion|establishment of protein localization in mitochondrion http://purl.obolibrary.org/obo/GO_0072655 OBA:1000142 biolink:OntologyClass vesicle size The size of a vesicle. go-plus.json vesicle size trait|size of vesicle http://purl.obolibrary.org/obo/OBA_1000142 GO:0072654 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072654 GO:0072653 biolink:BiologicalProcess interferon-omega production The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IFN-omega production|interferon-omega secretion|IFNW production http://purl.obolibrary.org/obo/GO_0072653 gocheck_do_not_annotate GO:0072652 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072652 UBERON:0001199 biolink:AnatomicalEntity mucosa of stomach The mucosal layer that lines the stomach. go-plus.json mucosa of organ of stomach|ventriculus mucosa|organ mucosa of ventriculus|gastric mucous membrane|ventriculus mucosa of organ|tunica mucosa (gaster)|gastric mucosa|stomach mucosa of organ|ventriculus mucous membrane|organ mucosa of stomach|Magenschleimhaut|stomach organ mucosa|stomach mucous membrane|ventriculus organ mucosa|tunica mucosa gastris|mucous membrane of ventriculus|mucosa of ventriculus|mucosa of organ of ventriculus|tunica mucosa gastricae|mucous membrane of stomach|stomach mucosa http://purl.obolibrary.org/obo/UBERON_0001199 GO:0072651 biolink:BiologicalProcess interferon-tau production The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interferon-tau secretion|IFN-tau production|IFNT production|IFN-tau secretion http://purl.obolibrary.org/obo/GO_0072651 gocheck_do_not_annotate UBERON:0001183 biolink:AnatomicalEntity inferior mesenteric artery Mesenteric artery that supplies the large intestine from the left colic (or splenic) flexure to the upper part of the rectum, which includes the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory of distribution overlaps (forms a watershed) with the middle colic artery, and therefore the superior mesenteric artery. The SMA and IMA anastomose via the marginal artery (artery of Drummond). The territory of distribution of the IMA is more or less equivalent to the embryonic hindgut. [WP,unvetted]. go-plus.json arteria mesenterica inferior|inferior mesenteric arterial tree|IMA http://purl.obolibrary.org/obo/UBERON_0001183 UBERON:0001185 biolink:AnatomicalEntity right renal artery Renal artery that supplies the right kidney go-plus.json right renal arterial tree http://purl.obolibrary.org/obo/UBERON_0001185 UBERON:0001184 biolink:AnatomicalEntity renal artery One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates. go-plus.json renal arterial tree|renal arteries|arteria renalis http://purl.obolibrary.org/obo/UBERON_0001184 GO:0072649 biolink:BiologicalProcess interferon-kappa production The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interferon-kappa secretion|IFNK production|IFN-kappa production http://purl.obolibrary.org/obo/GO_0072649 gocheck_do_not_annotate GO:0072648 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072648 GO:0072647 biolink:BiologicalProcess interferon-epsilon production The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interferon-epsilon secretion|IFN-epsilon production|IFNE production http://purl.obolibrary.org/obo/GO_0072647 gocheck_do_not_annotate GO:0072646 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072646 GO:0072645 biolink:BiologicalProcess interferon-delta production The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interferon-delta secretion|IFN-delta production|IFND production http://purl.obolibrary.org/obo/GO_0072645 gocheck_do_not_annotate GO:0072644 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072644 GO:0072643 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072643 UBERON:0001187 biolink:AnatomicalEntity testicular artery One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad. go-plus.json internal spermatic|spermatic vessels|internal spermatic vessels|internal spermatic artery|internal spermatic arteries|spermatic artery|spermatic arteries|arteria testicularis|testicular arterial tree|testicular arteries http://purl.obolibrary.org/obo/UBERON_0001187 GO:0072642 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072642 UBERON:0001186 biolink:AnatomicalEntity left renal artery Renal artery that supplies the left kidney go-plus.json left renal arterial tree http://purl.obolibrary.org/obo/UBERON_0001186 GO:0072641 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072641 UBERON:0001189 biolink:AnatomicalEntity left testicular artery A testicular artery that supplies a left testicle. go-plus.json trunk of left testicular arterial tree|left spermatic artery http://purl.obolibrary.org/obo/UBERON_0001189 UBERON:0001188 biolink:AnatomicalEntity right testicular artery A testicular artery that supplies a right testicle. go-plus.json right spermatic artery|trunk of right testicular arterial tree http://purl.obolibrary.org/obo/UBERON_0001188 GO:0072640 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072640 GO:0072672 biolink:BiologicalProcess neutrophil extravasation The migration of a neutrophil from the blood vessels into the surrounding tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0072672 GO:0072671 biolink:BiologicalProcess mitochondria-associated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions. go-plus.json MAD|mitochondria-associated protein catabolic process|mitochondrion-associated protein catabolic process|mitochondria-associated protein degradation http://purl.obolibrary.org/obo/GO_0072671 GO:0072670 biolink:BiologicalProcess mitochondrial tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base). go-plus.json mitochondrial tRNA t6A modification http://purl.obolibrary.org/obo/GO_0072670 UBERON:2001156 biolink:AnatomicalEntity posterior lateral line placode go-plus.json http://purl.obolibrary.org/obo/UBERON_2001156 UBERON:2001157 biolink:AnatomicalEntity posterior lateral line primordium A migrating group of cells originating from the posterior lateral line placode. The primordium deposits seven to nine neuromasts and interneuromasts between them during its posterior migration to the tail. Gompel et al, 2001. go-plus.json posterior lateral line primordia http://purl.obolibrary.org/obo/UBERON_2001157 UBERON:0001172 biolink:AnatomicalEntity hepatic acinus The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids. go-plus.json portal acinus|liver acinus http://purl.obolibrary.org/obo/UBERON_0001172 UBERON:0001171 biolink:AnatomicalEntity portal lobule The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001171 UBERON:0001174 biolink:AnatomicalEntity common bile duct the part of the biliary tree formed by the union of the cystic duct and the common hepatic duct go-plus.json ductus choledochus (biliaris)|ductus choledochus http://purl.obolibrary.org/obo/UBERON_0001174 UBERON:0001173 biolink:AnatomicalEntity biliary tree A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder. go-plus.json biliary tract http://purl.obolibrary.org/obo/UBERON_0001173 UBERON:0001170 biolink:AnatomicalEntity mesentery of small intestine The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]. go-plus.json mesentery (proper)|mesentery proper|small intestine mesentery|small intestinal mesentery http://purl.obolibrary.org/obo/UBERON_0001170 GO:0072679 biolink:BiologicalProcess thymocyte migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. go-plus.json immature T cell migration|thymic lymphocyte migration|immature T lymphocyte migration|immature T-cell migration|immature T-lymphocyte migration http://purl.obolibrary.org/obo/GO_0072679 UBERON:0001179 biolink:AnatomicalEntity peritoneal cavity Anatomical cavity bounded by visceral and parietal peritoneum go-plus.json cavitas peritonealis|saccus serosus peritonei http://purl.obolibrary.org/obo/UBERON_0001179 GO:0072678 biolink:BiologicalProcess T cell migration The movement of a T cell within or between different tissues and organs of the body. go-plus.json T-lymphocyte migration|T lymphocyte migration|T-cell migration http://purl.obolibrary.org/obo/GO_0072678 GO:0072677 biolink:BiologicalProcess eosinophil migration The movement of an eosinophil within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0072677 GO:0072676 biolink:BiologicalProcess lymphocyte migration The movement of a lymphocyte within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0072676 UBERON:0001176 biolink:AnatomicalEntity right hepatic duct The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct. go-plus.json ductus hepaticus dexter http://purl.obolibrary.org/obo/UBERON_0001176 GO:0072675 biolink:BiologicalProcess osteoclast fusion The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast. go-plus.json http://purl.obolibrary.org/obo/GO_0072675 UBERON:0001175 biolink:AnatomicalEntity common hepatic duct Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]. go-plus.json ductus hepaticus communis|hepatic duct http://purl.obolibrary.org/obo/UBERON_0001175 GO:0072674 biolink:BiologicalProcess multinuclear osteoclast differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. go-plus.json multinuclear osteoclast morphogenesis|multinuclear osteoclast formation http://purl.obolibrary.org/obo/GO_0072674 UBERON:0001178 biolink:AnatomicalEntity visceral peritoneum The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space. go-plus.json visceral serous membrane of peritoneum http://purl.obolibrary.org/obo/UBERON_0001178 UBERON:0001177 biolink:AnatomicalEntity left hepatic duct The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct. go-plus.json ductus hepaticus sinister http://purl.obolibrary.org/obo/UBERON_0001177 GO:0072673 biolink:BiologicalProcess lamellipodium morphogenesis A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized. go-plus.json lamellipodium organization http://purl.obolibrary.org/obo/GO_0072673 GO:0072661 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072661 GO:0072660 biolink:BiologicalProcess maintenance of protein location in plasma membrane Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0072660 SO:0000375 biolink:SequenceFeature cytosolic_5_8S_rRNA Cytosolic 5.8S rRNA is an RNA component of the large subunit of cytosolic ribosomes in eukaryotes. http://en.wikipedia.org/wiki/5.8S_ribosomal_RNA go-plus.json cytosolic rRNA 5 8S|cytosolic 5.8S LSU rRNA|cytosolic 5.8S ribosomal RNA|cytosolic 5.8S rRNA http://purl.obolibrary.org/obo/SO_0000375 SOFA SO:0000370 biolink:SequenceFeature small_regulatory_ncRNA A non-coding RNA less than 200 nucleotides long, usually with a specific secondary structure, that acts to regulate gene expression. These include short ncRNAs such as piRNA, miRNA and siRNAs (among others). go-plus.json small regulatory ncRNA http://purl.obolibrary.org/obo/SO_0000370 SOFA NCBITaxon:190304 biolink:OrganismalEntity Fusobacterium nucleatum subsp. nucleatum ATCC 25586 go-plus.json Fusobacterium nucleatum subsp. nucleatum str. ATCC 25586|Fusobacterium nucleatum subsp. nucleatum JCM 8532|Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586 http://purl.obolibrary.org/obo/NCBITaxon_190304 UBERON:0001161 biolink:AnatomicalEntity body of stomach The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. go-plus.json corpus gastricum|corpus gastricum (ventriculare)|stomach body|corpus ventriculare|gastric corpus|gastric body|corpus ventriculi http://purl.obolibrary.org/obo/UBERON_0001161 GO:0033097 biolink:CellularComponent amyloplast membrane Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0033097 GO:0033096 biolink:CellularComponent amyloplast envelope The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. go-plus.json http://purl.obolibrary.org/obo/GO_0033096 GO:0033095 biolink:CellularComponent aleurone grain A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes. go-plus.json aleurone body http://purl.obolibrary.org/obo/GO_0033095 GO:0033094 biolink:MolecularActivity butane-1,4-diamine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. MetaCyc:2.6.1.82-RXN|RHEA:12268|EC:2.6.1.82 go-plus.json putrescine transaminase activity|putrescine:alpha-ketoglutarate aminotransferase activity|putrescine-alpha-ketoglutarate transaminase activity|putrescine aminotransferase activity|YgjG|putrescine:2-oxoglutarate aminotransferase activity|PAT activity http://purl.obolibrary.org/obo/GO_0033094 GO:0033093 biolink:CellularComponent Weibel-Palade body A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses. Wikipedia:Weibel-Palade_body go-plus.json http://purl.obolibrary.org/obo/GO_0033093 GO:0033092 biolink:BiologicalProcess positive regulation of immature T cell proliferation in thymus Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus. go-plus.json positive regulation of thymocyte cell proliferation|positive regulation of thymocyte proliferation|positive regulation of thymic T cell proliferation http://purl.obolibrary.org/obo/GO_0033092 GO:0033091 biolink:BiologicalProcess positive regulation of immature T cell proliferation Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0033091 GO:0033090 biolink:BiologicalProcess positive regulation of extrathymic T cell differentiation Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation. go-plus.json positive regulation of extrathymic T cell development http://purl.obolibrary.org/obo/GO_0033090 GO:0072669 biolink:CellularComponent tRNA-splicing ligase complex A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. MetaCyc:ENTMULTI-CPLX go-plus.json tRNA splicing ligase complex http://purl.obolibrary.org/obo/GO_0072669 UBERON:0001169 biolink:AnatomicalEntity wall of large intestine An anatomical wall that is part of a large intestine [Automatically generated definition]. go-plus.json large intestine anatomical wall|large intestine wall|large intestinal wall|anatomical wall of large intestine http://purl.obolibrary.org/obo/UBERON_0001169 GO:0072668 biolink:BiologicalProcess obsolete tubulin complex biogenesis OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled. go-plus.json tubulin complex biogenesis http://purl.obolibrary.org/obo/GO_0072668 UBERON:0001168 biolink:AnatomicalEntity wall of small intestine An anatomical wall that is part of a small intestine [Automatically generated definition]. go-plus.json small intestinal wall|anatomical wall of small bowel|wall of small bowel|anatomical wall of small intestine|small bowel anatomical wall|small intestine wall|small intestine anatomical wall|small bowel wall http://purl.obolibrary.org/obo/UBERON_0001168 GO:0072667 biolink:BiologicalProcess maintenance of protein location in vacuole Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0072667 GO:0072666 biolink:BiologicalProcess establishment of protein localization to vacuole The directed movement of a protein to a specific location in a vacuole. go-plus.json establishment of protein localisation to vacuole http://purl.obolibrary.org/obo/GO_0072666 GO:0072665 biolink:BiologicalProcess protein localization to vacuole A process in which a protein is transported to, or maintained at, a location in a vacuole. go-plus.json protein localisation to vacuole http://purl.obolibrary.org/obo/GO_0072665 UBERON:0001165 biolink:AnatomicalEntity pyloric antrum the area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells go-plus.json gastric antrum|antrum of Willis|stomach pyloric antrum|antrum pylori|antrum of stomach|antrum|stomach antrum|antrum pyloricum http://purl.obolibrary.org/obo/UBERON_0001165 GO:0072664 biolink:BiologicalProcess maintenance of protein location in peroxisome Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0072664 UBERON:0001167 biolink:AnatomicalEntity wall of stomach the layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between go-plus.json stomach anatomical wall|stomach wall|ventriculus wall|anatomical wall of ventriculus|wall of ventriculus|gastric wall|anatomical wall of stomach|ventriculus anatomical wall http://purl.obolibrary.org/obo/UBERON_0001167 GO:0033099 biolink:CellularComponent attachment organelle A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0033099 goslim_pir GO:0072663 biolink:BiologicalProcess establishment of protein localization to peroxisome The directed movement of a protein to a specific location in a peroxisome. go-plus.json establishment of protein localisation to peroxisome http://purl.obolibrary.org/obo/GO_0072663 UBERON:0001166 biolink:AnatomicalEntity pylorus the stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum go-plus.json pars pylorica|stomach pyloric region|pyloric part of stomach|valvula pylori|pars pylorica gastricae|pyloric region http://purl.obolibrary.org/obo/UBERON_0001166 GO:0072662 biolink:BiologicalProcess protein localization to peroxisome A process in which a protein is transported to, or maintained at, a location in a peroxisome. go-plus.json protein localisation to peroxisome http://purl.obolibrary.org/obo/GO_0072662 GO:0033098 biolink:CellularComponent amyloplast inner membrane The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma. go-plus.json http://purl.obolibrary.org/obo/GO_0033098 CHEBI:48455 biolink:ChemicalSubstance 2-demethylmenaquinone-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_48455 chebi_ph7_3 GO:0008209 biolink:BiologicalProcess androgen metabolic process The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. go-plus.json androgen metabolism http://purl.obolibrary.org/obo/GO_0008209 GO:0008208 biolink:BiologicalProcess C21-steroid hormone catabolic process The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. go-plus.json C21-steroid hormone degradation|C21-steroid hormone catabolism|C21-steroid hormone breakdown http://purl.obolibrary.org/obo/GO_0008208 GO:0008207 biolink:BiologicalProcess C21-steroid hormone metabolic process The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. go-plus.json C21-steroid hormone metabolism http://purl.obolibrary.org/obo/GO_0008207 CHEBI:73418 biolink:ChemicalSubstance 1-(1-hydroxyalkyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73418 chebi_ph7_3 GO:0008206 biolink:BiologicalProcess bile acid metabolic process The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. go-plus.json bile acid metabolism http://purl.obolibrary.org/obo/GO_0008206 GO:0008205 biolink:BiologicalProcess ecdysone metabolic process The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development. go-plus.json ecdysone metabolism http://purl.obolibrary.org/obo/GO_0008205 GO:0008204 biolink:BiologicalProcess ergosterol metabolic process The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light. go-plus.json ergosterol metabolism http://purl.obolibrary.org/obo/GO_0008204 GO:0047812 biolink:MolecularActivity D-amino-acid N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid. MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN|RHEA:20704|EC:2.3.1.36 go-plus.json acetyl-CoA:D-amino-acid N-acetyltransferase activity|D-amino acid acetyltransferase activity|D-amino acid-alpha-N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047812 CHEBI:24480 biolink:ChemicalSubstance heme o go-plus.json http://purl.obolibrary.org/obo/CHEBI_24480 chebi_ph7_3 GO:0008203 biolink:BiologicalProcess cholesterol metabolic process The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. go-plus.json cholesterol metabolism http://purl.obolibrary.org/obo/GO_0008203 GO:0047811 biolink:MolecularActivity D-alanine gamma-glutamyltransferase activity Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+). MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.14|KEGG_REACTION:R01149|RHEA:23556 go-plus.json L-glutamine:D-alanine gamma-glutamyltransferase activity|D-alanine g-glutamyltransferase activity http://purl.obolibrary.org/obo/GO_0047811 GO:0047810 biolink:MolecularActivity D-alanine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate. MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN|RHEA:15869|EC:2.6.1.21 go-plus.json D-aspartate aminotransferase activity|D-amino acid aminotransferase activity|D-amino-acid transaminase activity|D-alanine aminotransferase activity|D-alanine-D-glutamate transaminase activity|D-aspartate transaminase activity|D-amino acid transaminase activity|D-alanine transaminase activity|D-aspartic aminotransferase activity http://purl.obolibrary.org/obo/GO_0047810 GO:0008202 biolink:BiologicalProcess steroid metabolic process The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. Wikipedia:Steroid_metabolism go-plus.json steroid metabolism http://purl.obolibrary.org/obo/GO_0008202 UBERON:0015834 biolink:AnatomicalEntity duodenum lamina propria A lamina propria that is part of a duodenum. go-plus.json lamina propria mucosae of duodenum|lamina propria of duodenum|duodenal lamina propria http://purl.obolibrary.org/obo/UBERON_0015834 GO:0008201 biolink:MolecularActivity heparin binding Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. go-plus.json heparan sulfate binding http://purl.obolibrary.org/obo/GO_0008201 UBERON:0015833 biolink:AnatomicalEntity foregut epithelium A epithelium that is part of a foregut. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015833 GO:0008200 biolink:MolecularActivity ion channel inhibitor activity Binds to and stops, prevents, or reduces the activity of an ion channel. go-plus.json http://purl.obolibrary.org/obo/GO_0008200 GO:0047819 biolink:MolecularActivity D-glutamate(D-aspartate) oxidase activity Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2. MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN|EC:1.4.3.15 go-plus.json D-glutamic-aspartic oxidase activity|D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)|D-monoaminodicarboxylic acid oxidase activity http://purl.obolibrary.org/obo/GO_0047819 GO:0047818 biolink:MolecularActivity D-fuconate dehydratase activity Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O. MetaCyc:D-FUCONATE-HYDRATASE-RXN|KEGG_REACTION:R03671|RHEA:12949|EC:4.2.1.67 go-plus.json D-fuconate hydratase activity|D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)|D-fuconate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047818 GO:0047817 biolink:MolecularActivity D-arginase activity Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea. EC:3.5.3.10|RHEA:12901|KEGG_REACTION:R02458|MetaCyc:D-ARGINASE-RXN go-plus.json D-arginine amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0047817 GO:0047816 biolink:MolecularActivity D-arabinose 1-dehydrogenase (NAD+) activity Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH. EC:1.1.1.116|MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN|RHEA:20457 go-plus.json NAD-pentose-dehydrogenase activity|arabinose(fucose)dehydrogenase activity|D-arabinose:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047816 GO:0047815 biolink:MolecularActivity D-arabinonolactonase activity Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+). MetaCyc:D-ARABINONOLACTONASE-RXN|KEGG_REACTION:R02714|RHEA:23108|EC:3.1.1.30 go-plus.json D-arabinono-1,4-lactone lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0047815 GO:0047814 biolink:MolecularActivity D-arabinokinase activity Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP. RHEA:24588|EC:2.7.1.54|KEGG_REACTION:R01573|MetaCyc:D-ARABINOKINASE-RXN go-plus.json D-arabinokinase (phosphorylating)|ATP:D-arabinose 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047814 GO:0047813 biolink:MolecularActivity D-arabinitol 4-dehydrogenase activity Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH. RHEA:17921|MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN|EC:1.1.1.11 go-plus.json http://purl.obolibrary.org/obo/GO_0047813 SO:0000275 biolink:SequenceFeature snoRNA A snoRNA (small nucleolar RNA) is any one of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. http://en.wikipedia.org/wiki/SnoRNA go-plus.json INSDC_qualifier:snoRNA|INSDC_feature:ncRNA|small nucleolar RNA http://purl.obolibrary.org/obo/SO_0000275 SOFA CHEBI:73423 biolink:ChemicalSubstance 1-(alk-1-enyl)-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73423 SO:0000274 biolink:SequenceFeature snRNA A small nuclear RNA molecule involved in pre-mRNA splicing and processing. http://en.wikipedia.org/wiki/SnRNA go-plus.json small nuclear RNA|INSDC_feature:ncRNA|INSDC_qualifier:snRNA http://purl.obolibrary.org/obo/SO_0000274 SOFA CHEBI:24499 biolink:ChemicalSubstance heparan sulfate proteoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_24499 SO:0000276 biolink:SequenceFeature miRNA Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors. http://en.wikipedia.org/wiki/StRNA|http://en.wikipedia.org/wiki/MiRNA go-plus.json INSDC_feature:ncRNA|micro RNA|INSDC_qualifier:miRNA|stRNA|microRNA|small temporal RNA http://purl.obolibrary.org/obo/SO_0000276 SOFA GO:0008219 biolink:BiologicalProcess cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). go-plus.json necrosis|accidental cell death http://purl.obolibrary.org/obo/GO_0008219 goslim_chembl|goslim_mouse|goslim_agr|goslim_plant|goslim_drosophila|goslim_generic GO:0008218 biolink:BiologicalProcess bioluminescence The production of light by certain enzyme-catalyzed reactions in cells. Wikipedia:Bioluminescence go-plus.json http://purl.obolibrary.org/obo/GO_0008218 goslim_chembl|goslim_metagenomics GO:0008217 biolink:BiologicalProcess regulation of blood pressure Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. Wikipedia:Blood_pressure#Regulation go-plus.json control of blood pressure|blood pressure regulation|blood pressure homeostasis http://purl.obolibrary.org/obo/GO_0008217 GO:0008216 biolink:BiologicalProcess spermidine metabolic process The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane. go-plus.json spermidine metabolism http://purl.obolibrary.org/obo/GO_0008216 GO:0008215 biolink:BiologicalProcess spermine metabolic process The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. go-plus.json spermine metabolism http://purl.obolibrary.org/obo/GO_0008215 GO:0047823 biolink:MolecularActivity D-glutamyltransferase activity Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide. RHEA:35623|MetaCyc:D-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.1 go-plus.json D-gamma-glutamyl transpeptidase activity|glutamine:D-glutamyl-peptide 5-glutamyltransferase activity|D-glutamyl transpeptidase activity http://purl.obolibrary.org/obo/GO_0047823 GO:0008214 biolink:BiologicalProcess protein dealkylation The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom. go-plus.json protein amino acid dealkylation http://purl.obolibrary.org/obo/GO_0008214 GO:0047822 biolink:MolecularActivity hypotaurine dehydrogenase activity Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine. MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN|KEGG_REACTION:R01681|EC:1.8.1.3|RHEA:17385|Reactome:R-HSA-1655453 go-plus.json hypotaurine:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047822 GO:0008213 biolink:BiologicalProcess protein alkylation The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom. go-plus.json protein amino acid alkylation http://purl.obolibrary.org/obo/GO_0008213 goslim_yeast GO:0047821 biolink:MolecularActivity D-glutamate oxidase activity Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2. RHEA:10028|KEGG_REACTION:R00279|EC:1.4.3.7|MetaCyc:D-GLUTAMATE-OXIDASE-RXN go-plus.json D-glutamic oxidase activity|D-glutamate:oxygen oxidoreductase (deaminating)|D-glutamic acid oxidase activity http://purl.obolibrary.org/obo/GO_0047821 GO:0047820 biolink:MolecularActivity D-glutamate cyclase activity Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O. EC:4.2.1.48|MetaCyc:D-GLUTAMATE-CYCLASE-RXN|KEGG_REACTION:R01583|RHEA:22360 go-plus.json D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)|D-glutamate hydro-lyase (cyclizing) http://purl.obolibrary.org/obo/GO_0047820 GO:0008212 biolink:BiologicalProcess mineralocorticoid metabolic process The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance. go-plus.json mineralocorticoid metabolism http://purl.obolibrary.org/obo/GO_0008212 GO:0008211 biolink:BiologicalProcess glucocorticoid metabolic process The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. go-plus.json glucocorticoid metabolism|glucocorticosteroid metabolism|glucocorticosteroid metabolic process http://purl.obolibrary.org/obo/GO_0008211 GO:0008210 biolink:BiologicalProcess estrogen metabolic process The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. go-plus.json oestrogen metabolism|oestrogen metabolic process|estrogen metabolism http://purl.obolibrary.org/obo/GO_0008210 CHEBI:24495 biolink:ChemicalSubstance heparan alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24495 GO:0047829 biolink:MolecularActivity D-nopaline dehydrogenase activity Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH. EC:1.5.1.19|RHEA:19637|MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN go-plus.json D-nopaline synthase activity|nopaline synthase activity|NOS activity|2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)|nopaline dehydrogenase activity|N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming) http://purl.obolibrary.org/obo/GO_0047829 GO:0047828 biolink:MolecularActivity D-lyxose ketol-isomerase activity Catalysis of the reaction: D-lyxose = D-xylulose. EC:5.3.1.15|KEGG_REACTION:R01898|RHEA:14201|MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN go-plus.json D-lyxose aldose-ketose-isomerase activity|D-lyxose isomerase activity http://purl.obolibrary.org/obo/GO_0047828 GO:0047827 biolink:MolecularActivity D-lysopine dehydrogenase activity Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate. MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN|EC:1.5.1.16|KEGG_REACTION:R00452|RHEA:17625 go-plus.json N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|D-lysopine synthase activity|D(+)-lysopine dehydrogenase activity|2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|lysopine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047827 UBERON:0015814 biolink:AnatomicalEntity outer ear epithelium A epithelium that is part of a external ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015814 GO:0047826 biolink:MolecularActivity D-lysine 5,6-aminomutase activity Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate. KEGG_REACTION:R02852|MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN|EC:5.4.3.4|RHEA:18241 go-plus.json adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity|D-2,6-diaminohexanoate 5,6-aminomutase activity|D-alpha-lysine mutase activity http://purl.obolibrary.org/obo/GO_0047826 UBERON:0015813 biolink:AnatomicalEntity middle ear epithelium A epithelium that is part of a middle ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015813 GO:0047825 biolink:MolecularActivity D-lactate-2-sulfatase activity Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate. EC:3.1.6.17|KEGG_REACTION:R01448|RHEA:20337|MetaCyc:D-LACTATE-2-SULFATASE-RXN go-plus.json (S)-2-O-sulfolactate 2-sulfohydrolase activity|D-lactate-2-sulphatase activity http://purl.obolibrary.org/obo/GO_0047825 GO:0047824 biolink:MolecularActivity D-iditol 2-dehydrogenase activity Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH. EC:1.1.1.15|RHEA:12725|MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0047824 CHEBI:48433 biolink:ChemicalSubstance angiotensin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48433 CHEBI:48436 biolink:ChemicalSubstance thiophenecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48436 CHEBI:24469 biolink:ChemicalSubstance haloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_24469 GO:0047834 biolink:MolecularActivity D-threo-aldose 1-dehydrogenase activity Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH. RHEA:19645|EC:1.1.1.122|MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN go-plus.json dehydrogenase, L-fucose|(2S,3R)-aldose dehydrogenase activity|L-fucose dehydrogenase activity|L-fucose (D-arabinose) dehydrogenase activity|D-threo-aldose:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047834 GO:0047833 biolink:MolecularActivity D-sorbitol dehydrogenase (acceptor) activity Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor. EC:1.1.99.21|MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN|RHEA:21320 go-plus.json D-sorbitol dehydrogenase activity|D-sorbitol:acceptor 1-oxidoreductase activity|D-sorbitol:(acceptor) 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047833 GO:0047832 biolink:MolecularActivity D-pinitol dehydrogenase activity Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH. MetaCyc:D-PINITOL-DEHYDROGENASE-RXN|EC:1.1.1.142|RHEA:20437|KEGG_REACTION:R03498 go-plus.json 1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity|5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047832 GO:0047831 biolink:MolecularActivity D-ornithine 4,5-aminomutase activity Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate. MetaCyc:ORNMUTST-RXN|EC:5.4.3.5|RHEA:14893|KEGG_REACTION:R02461 go-plus.json D-ornithine aminomutase activity|D-alpha-ornithine 5,4-aminomutase activity http://purl.obolibrary.org/obo/GO_0047831 GO:0047830 biolink:MolecularActivity D-octopine dehydrogenase activity Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH. RHEA:16285|MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN|EC:1.5.1.11 go-plus.json 2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|D-octopine synthase activity|octopine dehydrogenase activity|ODH activity|N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|octopine:NAD oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047830 CHEBI:48430 biolink:ChemicalSubstance 4-methyl-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48430 CHEBI:24462 biolink:ChemicalSubstance gulonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24462 CHEBI:24461 biolink:ChemicalSubstance gulonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24461 CHEBI:48432 biolink:ChemicalSubstance angiotensin II go-plus.json http://purl.obolibrary.org/obo/CHEBI_48432 CHEBI:48431 biolink:ChemicalSubstance formimidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48431 UBERON:0015807 biolink:AnatomicalEntity ear epithelium A epithelium that is part of a ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015807 GO:0047839 biolink:MolecularActivity dATP(dGTP)-DNA purinetransferase activity Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA. MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN|EC:2.6.99.1 go-plus.json dATP(dGTP):depurinated-DNA purine transferase activity|dATP(dGTP)--DNA purine transferase activity http://purl.obolibrary.org/obo/GO_0047839 UBERON:0015808 biolink:AnatomicalEntity eye epithelium A epithelium that is part of a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015808 GO:0047838 biolink:MolecularActivity D-xylose 1-dehydrogenase (NAD) activity Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH. RHEA:13861|EC:1.1.1.175|MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN go-plus.json D-xylose:NAD+ 1-oxidoreductase activity|NAD-linked D-xylose dehydrogenase activity|(NAD)-linked D-xylose dehydrogenase activity|NAD-D-xylose dehydrogenase activity|D-xylose dehydrogenase activity|NAD-D-xylose http://purl.obolibrary.org/obo/GO_0047838 GO:0047837 biolink:MolecularActivity D-xylose 1-dehydrogenase (NADP+) activity Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH. RHEA:22000|EC:1.1.1.179|MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01430 go-plus.json D-xylose:NADP+ 1-oxidoreductase activity|D-xylose-NADP dehydrogenase activity|D-xylose:NADP+ oxidoreductase activity|D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047837 GO:0047836 biolink:MolecularActivity D-tryptophan N-malonyltransferase activity Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+). RHEA:23320|KEGG_REACTION:R02482|EC:2.3.1.112|MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN go-plus.json malonyl-CoA:D-tryptophan N-malonyltransferase activity http://purl.obolibrary.org/obo/GO_0047836 GO:0047835 biolink:MolecularActivity D-tryptophan N-acetyltransferase activity Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+). KEGG_REACTION:R02481|RHEA:10060|MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.34 go-plus.json D-tryptophan acetyltransferase activity|acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity|acetyl-CoA:D-tryptophan N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047835 CHEBI:48423 biolink:ChemicalSubstance 3-hydroxy-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48423 SO:0000296 biolink:SequenceFeature origin_of_replication A region of nucleic acid from which replication initiates; includes sequences that are recognized by replication proteins, the site from which the first separation of complementary strands occurs, and specific replication start sites. http://en.wikipedia.org/wiki/Origin_of_replication go-plus.json ori|INSDC_feature:rep_origin|origin of replication http://purl.obolibrary.org/obo/SO_0000296 SOFA CHEBI:48422 biolink:ChemicalSubstance angiogenesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_48422 CHEBI:48427 biolink:ChemicalSubstance N-formimidoyl-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48427 CHEBI:48429 biolink:ChemicalSubstance N-formyl-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48429 CHEBI:24479 biolink:ChemicalSubstance heme a go-plus.json http://purl.obolibrary.org/obo/CHEBI_24479 GO:0047845 biolink:MolecularActivity deoxylimonate A-ring-lactonase activity Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+). EC:3.1.1.46|KEGG_REACTION:R03803|RHEA:14997|MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN go-plus.json deoxylimonate A-ring-lactonohydrolase activity http://purl.obolibrary.org/obo/GO_0047845 CHEBI:24470 biolink:ChemicalSubstance haloamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24470 GO:0047844 biolink:MolecularActivity deoxycytidine deaminase activity Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3. EC:3.5.4.14|RHEA:13433|MetaCyc:CYTIDEAM-RXN go-plus.json deoxycytidine aminohydrolase activity http://purl.obolibrary.org/obo/GO_0047844 GO:0047843 biolink:MolecularActivity dehydrogluconate dehydrogenase activity Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2). RHEA:12368|MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN|KEGG_REACTION:R07153|EC:1.1.99.4 go-plus.json 2-keto-D-gluconate dehydrogenase activity|alpha-ketogluconate dehydrogenase activity|ketogluconate dehydrogenase activity|2-oxogluconate dehydrogenase activity|2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047843 GO:0047842 biolink:MolecularActivity dehydro-L-gulonate decarboxylase activity Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2). EC:4.1.1.34|RHEA:11084|Reactome:R-HSA-5662473|MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN|KEGG_REACTION:R01905 go-plus.json keto-L-gulonate decarboxylase activity|3-keto-L-gulonate decarboxylase activity|3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)|3-dehydro-L-gulonate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0047842 GO:0047841 biolink:MolecularActivity dehydrogluconokinase activity Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+). KEGG_REACTION:R02658|RHEA:10788|EC:2.7.1.13|MetaCyc:DEHYDOGLUCONOKINASE-RXN go-plus.json ketogluconokinase (phosphorylating)|dehydogluconokinase activity|ATP:2-dehydro-D-gluconate 6-phosphotransferase activity|ketogluconokinase activity|2-ketogluconokinase activity|2-ketogluconate kinase activity http://purl.obolibrary.org/obo/GO_0047841 GO:0047840 biolink:MolecularActivity dCTP diphosphatase activity Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate. RHEA:22636|EC:3.6.1.12|MetaCyc:DCTP-PYROPHOSPHATASE-RXN|Reactome:R-HSA-6786257 go-plus.json dCTP pyrophosphatase activity|deoxycytidine triphosphatase activity|deoxy-CTPase activity|deoxycytidine-triphosphatase activity|dCTP nucleotidohydrolase activity|dCTPase activity http://purl.obolibrary.org/obo/GO_0047840 CHEBI:24473 biolink:ChemicalSubstance halogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_24473 CHEBI:24472 biolink:ChemicalSubstance halohydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_24472 CHEBI:24471 biolink:ChemicalSubstance halogen molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_24471 CHEBI:48420 biolink:ChemicalSubstance biphenylyltetrazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_48420 GO:0047849 biolink:MolecularActivity dextransucrase activity Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1). MetaCyc:DEXTRANSUCRASE-RXN|EC:2.4.1.5 go-plus.json SGE|CEP|sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|sucrose 6-glucosyltransferase activity|sucrose-1,6-alpha-glucan glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047849 GO:0047848 biolink:MolecularActivity dephospho-[reductase kinase] kinase activity Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]. EC:2.7.11.3|MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN go-plus.json hydroxymethylglutaryl coenzyme A reductase kinase kinase activity|AMP-activated kinase activity|reductase kinase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity|STK30|reductase kinase activity|dephospho-reductase kinase kinase activity|AMP-activated protein kinase kinase activity|ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047848 GO:0047847 biolink:MolecularActivity deoxyuridine phosphorylase activity Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate. RHEA:22824|EC:2.4.2.23|MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN go-plus.json deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity|2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity|deoxyuridine:phosphate deoxy-D-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0047847 GO:0047846 biolink:MolecularActivity deoxynucleotide 3'-phosphatase activity Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate. EC:3.1.3.34|MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN|RHEA:10092 go-plus.json 3'-deoxynucleotidase activity|deoxyribonucleotide 3'-phosphohydrolase activity|3'-deoxyribonucleotidase activity http://purl.obolibrary.org/obo/GO_0047846 UBERON:0015870 biolink:AnatomicalEntity lymph node of head A lymph node that is part of a head. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015870 CHEBI:24442 biolink:ChemicalSubstance guanidinoethyl methyl phosphates go-plus.json http://purl.obolibrary.org/obo/CHEBI_24442 UBERON:0001229 biolink:AnatomicalEntity renal corpuscle the structure containing the glomerular capsule and the glomerulus that serves as the initial blood-filtering component of a nephron go-plus.json kidney corpuscle|corpusculum renis|cortical renal corpuscle|Malphigian corpuscle|Malpighian corpuscle|corpusculum renale http://purl.obolibrary.org/obo/UBERON_0001229 GO:0047856 biolink:MolecularActivity dihydrocoumarin hydrolase activity Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+). MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN|EC:3.1.1.35|KEGG_REACTION:R03692|RHEA:10360 go-plus.json dihydrocoumarin lactonohydrolase activity|dihydrocoumarin lipase activity http://purl.obolibrary.org/obo/GO_0047856 GO:0047855 biolink:MolecularActivity dihydrobunolol dehydrogenase activity Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH. MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN|EC:1.1.1.160|RHEA:15925|KEGG_REACTION:R04623 go-plus.json (+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity|bunolol reductase activity http://purl.obolibrary.org/obo/GO_0047855 GO:0047854 biolink:MolecularActivity diguanidinobutanase activity Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea. MetaCyc:DIGUANIDINOBUTANASE-RXN|KEGG_REACTION:R01418|RHEA:13597|EC:3.5.3.20 go-plus.json 1,4-diguanidinobutane amidinohydrolase activity http://purl.obolibrary.org/obo/GO_0047854 GO:0047853 biolink:MolecularActivity difructose-anhydride synthase activity Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose. EC:3.2.1.134|RHEA:15041|MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN go-plus.json inulobiose hydrolase activity|bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity http://purl.obolibrary.org/obo/GO_0047853 GO:0047852 biolink:MolecularActivity diferric-transferrin reductase activity Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH. RHEA:13841|MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN|EC:1.16.1.2 go-plus.json transferrin[Fe(II)]2:NAD+ oxidoreductase activity|diferric transferrin reductase activity|transferrin reductase activity|NADH diferric transferrin reductase activity http://purl.obolibrary.org/obo/GO_0047852 UBERON:0015871 biolink:AnatomicalEntity facial lymph node Any of the lymph nodes that are part of a face. go-plus.json buccal lymph node http://purl.obolibrary.org/obo/UBERON_0015871 GO:0047851 biolink:MolecularActivity dicarboxylate-CoA ligase activity Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA. EC:6.2.1.23|MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN|RHEA:14289 go-plus.json omega-dicarboxylate:CoA ligase (AMP-forming)|carboxylyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0047851 GO:0047850 biolink:MolecularActivity diaminopimelate dehydrogenase activity Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+). MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN|EC:1.4.1.16|KEGG_REACTION:R02755|RHEA:13561 go-plus.json meso-diaminopimelate dehydrogenase activity|meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)|meso-alpha,epsilon-diaminopimelate dehydrogenase activity|meso-diaminopimelate D-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047850 GO:0047859 biolink:MolecularActivity obsolete dihydroxyphenylalanine ammonia-lyase activity OBSOLETE. Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine = trans-caffeate + NH3. EC:4.3.1.11 go-plus.json 3,4-dihydroxy-L-phenylalanine ammonia-lyase activity|beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase activity|dihydroxyphenylalanine ammonia-lyase activity|3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming) http://purl.obolibrary.org/obo/GO_0047859 GO:0047858 biolink:MolecularActivity dihydroxyfumarate decarboxylase activity Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2). MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN|RHEA:13845|EC:4.1.1.54|KEGG_REACTION:R03127 go-plus.json dihydroxyfumarate carboxy-lyase activity|dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming) http://purl.obolibrary.org/obo/GO_0047858 GO:0047857 biolink:MolecularActivity dihydrouracil oxidase activity Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil. MetaCyc:DIHYDROURACIL-OXIDASE-RXN|KEGG_REACTION:R00975|EC:1.3.3.7|RHEA:12384 go-plus.json 5,6-dihydrouracil:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047857 UBERON:0001235 biolink:AnatomicalEntity adrenal cortex the thick outer layer of the adrenal gland that produces and secretes steroid hormones such as corticosterone, estrone and aldosterone go-plus.json suprarenal cortex|cortex (glandula suprarenalis)|adrenal gland cortex|cortex of adrenal gland|cortex of suprarenal gland|suprarenal|cortex glandulae suprarenalis http://purl.obolibrary.org/obo/UBERON_0001235 UBERON:0001234 biolink:AnatomicalEntity left adrenal gland An adrenal gland that is in the left side of the abdomen go-plus.json left suprarenal gland|glandula suprarenalis sinister http://purl.obolibrary.org/obo/UBERON_0001234 UBERON:0001236 biolink:AnatomicalEntity adrenal medulla the inner portion of the adrenal gland that consists mainly of chromaffin cells which produce, store and secrete neurotransmitters such as epinephrine and norepinephrine go-plus.json medulla of glandula suprarenalis|medulla of adrenal gland|medulla (glandula suprarenalis)|medulla glandulae suprarenalis|adrenal gland medulla|adrenal central medulla|chromaffin cells|suprarenal medulla|medulla of suprarenal gland http://purl.obolibrary.org/obo/UBERON_0001236 UBERON:0001231 biolink:AnatomicalEntity nephron tubule An epithelial tube that is part of the nephron, the functional part of the kidney. go-plus.json kidney tubule|uriniferous tubule|tubulus renalis|renal tubule http://purl.obolibrary.org/obo/UBERON_0001231 UBERON:0001230 biolink:AnatomicalEntity glomerular capsule A cup-like sac at the expanded beginning of a tubular component of a nephron that contains the glomerulus go-plus.json Muellerian capsule|Mueller capsule|Malphigian capsule|pronephric glomerular capsule|Bowmans capsule|Malpighian capsule|Bowman's capsule|capsula glomeruli|Bowman's capsule|renal glomerular capsule|capsula glomerularis http://purl.obolibrary.org/obo/UBERON_0001230 UBERON:0001233 biolink:AnatomicalEntity right adrenal gland An adrenal gland that is in the right side of the abdomen go-plus.json glandula suprarenalis dexter|right suprarenal gland http://purl.obolibrary.org/obo/UBERON_0001233 UBERON:0001232 biolink:AnatomicalEntity collecting duct of renal tubule The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient go-plus.json arcuate renal tubule|collecting tubule|tubulus renalis arcuatus|kidney collecting tubule|collecting duct|ureteric tree|tubulus renalis colligens|kidney collecting duct|junctional tube|collecting duct system|renal collecting tubule http://purl.obolibrary.org/obo/UBERON_0001232 CHEBI:24455 biolink:ChemicalSubstance guanosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24455 CHEBI:48400 biolink:ChemicalSubstance 3-(3,4-dihydroxyphenyl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48400 CHEBI:48403 biolink:ChemicalSubstance UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48403 CHEBI:48402 biolink:ChemicalSubstance UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48402 CHEBI:48405 biolink:ChemicalSubstance 1D-myo-inositol 1,2,3,5,6-pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48405 CHEBI:48404 biolink:ChemicalSubstance UDP-alpha-D-mannuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48404 CHEBI:24458 biolink:ChemicalSubstance guanosines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24458 CHEBI:48407 biolink:ChemicalSubstance antiparkinson drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_48407 UBERON:0001218 biolink:AnatomicalEntity middle colic vein The middle colic vein drains the transverse colon. It is a tributary of the superior mesenteric vein, and follows the path of its corresponding artery, the middle colic artery. [WP,unvetted]. go-plus.json vena colica media (intermedia)|vena colica media http://purl.obolibrary.org/obo/UBERON_0001218 GO:0047867 biolink:MolecularActivity dimethylmalate dehydrogenase activity Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH. MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN|EC:1.1.1.84|KEGG_REACTION:R01211|RHEA:13321 go-plus.json (R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)|beta,beta-dimethylmalate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047867 GO:0047866 biolink:MolecularActivity dimethylglycine oxidase activity Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine. EC:1.5.3.10|KEGG_REACTION:R01564|RHEA:17077|MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN go-plus.json N,N-dimethylglycine:oxygen oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0047866 GO:0047865 biolink:MolecularActivity dimethylglycine dehydrogenase activity Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein. KEGG_REACTION:R01565|Reactome:R-HSA-6797653|EC:1.5.8.4|MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN|RHEA:52856 go-plus.json N,N-dimethylglycine oxidase activity|N,N-dimethylglycine:acceptor oxidoreductase (demethylating)|N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0047865 GO:0047864 biolink:MolecularActivity dimethylaniline-N-oxide aldolase activity Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde. EC:4.1.2.24|KEGG_REACTION:R03345|RHEA:19321|MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN go-plus.json microsomal N-oxide dealkylase activity|N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)|microsomal oxidase II|N,N-dimethylaniline-N-oxide formaldehyde-lyase activity http://purl.obolibrary.org/obo/GO_0047864 GO:0047863 biolink:MolecularActivity dimethylallylcistransferase activity Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate. RHEA:11328|MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN|EC:2.5.1.28|KEGG_REACTION:R01659 go-plus.json dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity|neryl-diphosphate synthase activity http://purl.obolibrary.org/obo/GO_0047863 GO:0047862 biolink:MolecularActivity diisopropyl-fluorophosphatase activity Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride. KEGG_REACTION:R01533|EC:3.1.8.2|RHEA:24100|MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN go-plus.json isopropylphosphorofluoridase activity|diisopropyl-fluorophosphate fluorohydrolase activity|organophosphate acid anhydrase activity|DFPase activity|tabunase activity|OPA anhydrase activity|diisopropyl phosphorofluoridate hydrolase activity|diisopropylphosphofluoridase activity|organophosphorus acid anhydrolase activity|diisopropylfluorophosphonate dehalogenase activity|somanase activity|OPAA activity|dialkylfluorophosphatase activity http://purl.obolibrary.org/obo/GO_0047862 UBERON:0015860 biolink:AnatomicalEntity visceral abdominal lymph node go-plus.json http://purl.obolibrary.org/obo/UBERON_0015860 GO:0047861 biolink:MolecularActivity diiodotyrosine transaminase activity Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate. KEGG_REACTION:R03207|EC:2.6.1.24|RHEA:19781|MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN go-plus.json halogenated tyrosine aminotransferase activity|diiodotyrosine aminotransferase activity|halogenated tyrosine transaminase activity|3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047861 GO:0047860 biolink:MolecularActivity diiodophenylpyruvate reductase activity Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH. EC:1.1.1.96|MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN|KEGG_REACTION:R03431|RHEA:20293 go-plus.json 2-oxo acid reductase activity|KAR|3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity|aromatic alpha-keto acid http://purl.obolibrary.org/obo/GO_0047860 GO:0047869 biolink:MolecularActivity dimethylpropiothetin dethiomethylase activity Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+). MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN|KEGG_REACTION:R02574|RHEA:19965|EC:4.4.1.3 go-plus.json S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity|S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)|desulfhydrase activity http://purl.obolibrary.org/obo/GO_0047869 GO:0047868 biolink:MolecularActivity dimethylmaleate hydratase activity Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O. EC:4.2.1.85|RHEA:20253|KEGG_REACTION:R03069|MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN go-plus.json (2R,3S)-2,3-dimethylmalate hydro-lyase activity|(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming) http://purl.obolibrary.org/obo/GO_0047868 UBERON:0001224 biolink:AnatomicalEntity renal pelvis A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]. go-plus.json pyelum|kidney pelvis|p. renallis|pelvis of ureter http://purl.obolibrary.org/obo/UBERON_0001224 UBERON:0001223 biolink:AnatomicalEntity left ureter An ureter that is part of a left side of organism [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001223 UBERON:0001225 biolink:AnatomicalEntity cortex of kidney Outer cortical portion of the kidney, between the renal capsule and the renal medulla. go-plus.json kidney cortex|renal cortex|cortex renalis http://purl.obolibrary.org/obo/UBERON_0001225 UBERON:0001222 biolink:AnatomicalEntity right ureter An ureter that is part of a right side of organism [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001222 GO:0047870 biolink:MolecularActivity discadenine synthase activity Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+). RHEA:19581|MetaCyc:DISCADENINE-SYNTHASE-RXN|KEGG_REACTION:R03726|EC:2.5.1.24 go-plus.json S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity|S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas|discadenine synthetase activity http://purl.obolibrary.org/obo/GO_0047870 UBERON:0001209 biolink:AnatomicalEntity serosa of large intestine A serous membrane that is part of a large intestine [Automatically generated definition]. go-plus.json large intestine serous membrane|serous coat of large intestine|tunica serosa intestini crassi|visceral peritoneum of large intestine|large intestine serosa|serous membrane of large intestine|large intestinal serosa http://purl.obolibrary.org/obo/UBERON_0001209 CHEBI:73477 biolink:ChemicalSubstance terminal acetylenic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_73477 chebi_ph7_3 UBERON:0001206 biolink:AnatomicalEntity serosa of small intestine A serous membrane that is part of a small intestine [Automatically generated definition]. go-plus.json small intestine serosa|visceral peritoneum of small intestine|serous membrane of small bowel|small bowel serosa|serous membrane of small intestine|small bowel serous membrane|small intestinal serosa|tunica serosa (intestinum tenue)|small intestine serous membrane|serous coat of small intestine|serosa of small bowel|tunica serosa intestini tenuis http://purl.obolibrary.org/obo/UBERON_0001206 UBERON:0001205 biolink:AnatomicalEntity submucosa of small intestine submucosal tissue in the small intestines. go-plus.json tela submucosa intestini tenuis|submucosa of small bowel|small intestinal submucosa|small bowel submucosa|tela submucosa (intestinum tenue)|small intestine submucosa http://purl.obolibrary.org/obo/UBERON_0001205 UBERON:0001208 biolink:AnatomicalEntity submucosa of large intestine A submucosa that is part of a large intestine [Automatically generated definition]. go-plus.json large intestinal submucosa|large intestine submucosa|tela submucosa intestini crassi|submucous layer of large intestine http://purl.obolibrary.org/obo/UBERON_0001208 UBERON:0001207 biolink:AnatomicalEntity mucosa of large intestine A mucosa that is part of a large intestine [Automatically generated definition]. go-plus.json large intestine organ mucosa|organ mucosa of large intestine|large intestine mucosa of organ|large intestine mucous membrane|tunica mucosa intestini crassi|large intestine mucosa|mucous membrane of large intestine|large intestinal mucosa|mucosa of organ of large intestine http://purl.obolibrary.org/obo/UBERON_0001207 GO:0047878 biolink:MolecularActivity erythritol kinase activity Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+). MetaCyc:ERYTHRITOL-KINASE-RXN|RHEA:20708|EC:2.7.1.27|KEGG_REACTION:R02430 go-plus.json ATP:erythritol 4-phosphotransferase activity|erythritol kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0047878 GO:0047877 biolink:MolecularActivity ephedrine dehydrogenase activity Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH. MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN|EC:1.5.1.18|KEGG_REACTION:R03614|RHEA:16289 go-plus.json (-)-ephedrine:NAD+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047877 GO:0047876 biolink:MolecularActivity endoglycosylceramidase activity Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose. RHEA:22288|MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN|EC:3.2.1.123 go-plus.json glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity|endo-glucosylceramidase activity|oligoglycosylglucosylceramide glycohydrolase activity|endoglycoceramidase activity|EGCase activity http://purl.obolibrary.org/obo/GO_0047876 GO:0047875 biolink:MolecularActivity ecdysone oxidase activity Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2). EC:1.1.3.16|MetaCyc:ECDYSONE-OXIDASE-RXN|RHEA:11796|KEGG_REACTION:R02373 go-plus.json beta-ecdysone oxidase activity|ecdysone:oxygen 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047875 GO:0047874 biolink:MolecularActivity dolichyldiphosphatase activity Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate. Reactome:R-HSA-446200|MetaCyc:DOLICHYLDIPHOSPHATASE-RXN|EC:3.6.1.43|RHEA:14385 go-plus.json dolichyl-diphosphate phosphohydrolase activity|dolichol diphosphatase activity|dolichyl diphosphate phosphohydrolase activity|dolichyl pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0047874 GO:0047873 biolink:MolecularActivity dolichyl-phosphatase activity Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate. MetaCyc:DOLICHYL-PHOSPHATASE-RXN|RHEA:13797|EC:3.1.3.51 go-plus.json Dol-P phosphatase activity|dolichol monophosphatase activity|dolichol phosphate phosphatase activity|dolichol phosphatase activity|Dol-P-P phosphohydrolase activity|polyprenylphosphate phosphatase activity|polyisoprenyl phosphate phosphatase activity|dolichyl pyrophosphate phosphatase activity|dolichyl monophosphate phosphatase activity|dolichyl phosphate phosphatase activity|dolichyl-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047873 GO:0047872 biolink:MolecularActivity dolichol O-acyltransferase activity Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate. MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN|RHEA:16685|EC:2.3.1.123 go-plus.json acyl-CoA:dolichol acyltransferase activity|palmitoyl-CoA:dolichol O-palmitoyltransferase activity http://purl.obolibrary.org/obo/GO_0047872 GO:0047871 biolink:MolecularActivity disulfoglucosamine-6-sulfatase activity Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate. MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN|RHEA:15517|KEGG_REACTION:R03216|EC:3.1.6.11 go-plus.json 6,N-disulfoglucosamine 6-O-sulfohydrolase activity|disulphoglucosamine-6-sulphatase activity|N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity|N-sulfoglucosamine-6-sulfatase activity http://purl.obolibrary.org/obo/GO_0047871 GO:0047879 biolink:MolecularActivity erythronolide synthase activity Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B. MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN|EC:2.3.1.94|RHEA:23068 go-plus.json erythronolide condensing enzyme activity|malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing) http://purl.obolibrary.org/obo/GO_0047879 UBERON:0001213 biolink:AnatomicalEntity intestinal villus the tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold go-plus.json small intestine villus|villi intestinales|intestinal villus layer|villus|enteric villous|enteric villi|villus intestinalis (intestinum tenue)|enteric villus|villi intestinales|intestinal villi http://purl.obolibrary.org/obo/UBERON_0001213 UBERON:0001212 biolink:AnatomicalEntity duodenal gland A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]. go-plus.json gland of Brunner|Brunner's gland|submucosal gland of duodenum|glandula duodenales|glandula duodenales Brunneri http://purl.obolibrary.org/obo/UBERON_0001212 UBERON:0001215 biolink:AnatomicalEntity inferior mesenteric vein A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. go-plus.json lower mesenteric vein|vena mesenterica inferior http://purl.obolibrary.org/obo/UBERON_0001215 CHEBI:73474 biolink:ChemicalSubstance acetylenic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_73474 chebi_ph7_3 UBERON:0001211 biolink:AnatomicalEntity Peyer's patch the protruding lymphoid tissue located on the mucosa of the intestine that is composed of densely packed B cell follicles go-plus.json aggregated lymphoid nodule|Peyers gland|aggregated lymphoid follicle of intestine|noduli lymphoidei aggregati|Peyers patch http://purl.obolibrary.org/obo/UBERON_0001211 GO:0047881 biolink:MolecularActivity estradiol 17-alpha-dehydrogenase activity Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+. EC:1.1.1.148|MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN go-plus.json estradiol 17alpha-oxidoreductase activity|17alpha-hydroxysteroid oxidoreductase activity|estradiol 17alpha-dehydrogenase activity|17alpha-estradiol dehydrogenase activity|17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity|17alpha-hydroxy steroid oxidoreductase activity|estradiol 17a-dehydrogenase activity|17alpha-hydroxy steroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047881 GO:0047880 biolink:MolecularActivity erythrulose reductase activity Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH. RHEA:18005|KEGG_REACTION:R08573|EC:1.1.1.162|MetaCyc:ERYTHRULOSE-REDUCTASE-RXN go-plus.json erythritol:NADP+ oxidoreductase activity|D-erythrulose reductase activity http://purl.obolibrary.org/obo/GO_0047880 CHEBI:24433 biolink:ChemicalSubstance group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24433 CHEBI:24432 biolink:ChemicalSubstance biological role go-plus.json http://purl.obolibrary.org/obo/CHEBI_24432 CHEBI:24431 biolink:ChemicalSubstance chemical entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_24431 chebi_ph7_3 CHEBI:24436 biolink:ChemicalSubstance guanidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24436 GO:0047889 biolink:MolecularActivity ferredoxin-nitrate reductase activity Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin. MetaCyc:1.7.7.2-RXN|EC:1.7.7.2|RHEA:21828 go-plus.json nitrite:ferredoxin oxidoreductase activity|assimilatory nitrate reductase activity|nitrate (ferredoxin) reductase activity|assimilatory ferredoxin-nitrate reductase activity http://purl.obolibrary.org/obo/GO_0047889 GO:0047888 biolink:MolecularActivity fatty acid peroxidase activity Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal. RHEA:23960|EC:1.11.1.3|MetaCyc:FATTY-ACID-PEROXIDASE-RXN|KEGG_REACTION:R01703 go-plus.json hexadecanoate:hydrogen-peroxide oxidoreductase activity|long chain fatty acid peroxidase activity|fatty-acid peroxidase activity http://purl.obolibrary.org/obo/GO_0047888 GO:0047887 biolink:MolecularActivity farnesyl diphosphate kinase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP. KEGG_REACTION:R02303|RHEA:21544|MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN|EC:2.7.4.18 go-plus.json farnesyl-diphosphate kinase activity|ATP:farnesyl-diphosphate phosphotransferase activity|farnesyl pyrophosphate kinase activity http://purl.obolibrary.org/obo/GO_0047887 GO:0047886 biolink:MolecularActivity farnesol dehydrogenase activity Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH. RHEA:14697|KEGG_REACTION:R03264|EC:1.1.1.216|MetaCyc:FARNESOL-DEHYDROGENASE-RXN go-plus.json farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity|NADP-farnesol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047886 GO:0047885 biolink:MolecularActivity farnesol 2-isomerase activity Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol. RHEA:13401|EC:5.2.1.9|KEGG_REACTION:R03265|MetaCyc:FARNESOL-2-ISOMERASE-RXN go-plus.json 2-trans,6-trans-farnesol 2-cis-trans-isomerase activity|farnesol isomerase activity http://purl.obolibrary.org/obo/GO_0047885 GO:0047884 biolink:MolecularActivity FAD diphosphatase activity Catalysis of the reaction: FAD + H2O = AMP + FMN. MetaCyc:FAD-PYROPHOSPHATASE-RXN|EC:3.6.1.18|RHEA:13889 go-plus.json flavine adenine dinucleotide pyrophosphatase activity|riboflavin adenine dinucleotide pyrophosphatase activity|riboflavine adenine dinucleotide pyrophosphatase activity|FAD nucleotidohydrolase activity|flavin adenine dinucleotide pyrophosphatase activity|FAD pyrophosphatase activity|FAD pyrophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047884 GO:0047883 biolink:MolecularActivity ethanolamine oxidase activity Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2. EC:1.4.3.8|MetaCyc:ETHANOLAMINE-OXIDASE-RXN|RHEA:18581 go-plus.json ethanolamine:oxygen oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0047883 GO:0047882 biolink:MolecularActivity estradiol 6-beta-monooxygenase activity Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O. MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN|RHEA:19137|KEGG_REACTION:R03086|EC:1.14.99.11 go-plus.json estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)|estradiol 6-beta-hydroxylase activity|estradiol 6beta-monooxygenase activity|estradiol 6beta-hydroxylase activity|estradiol 6b-monooxygenase activity|estradiol 6b-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047882 UBERON:0001202 biolink:AnatomicalEntity pyloric sphincter A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]. go-plus.json pyloric valve http://purl.obolibrary.org/obo/UBERON_0001202 UBERON:0001201 biolink:AnatomicalEntity serosa of stomach the outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum go-plus.json serosa of ventriculus anatomical wall|serous membrane of ventriculus wall|serous coat of stomach|serous membrane of anatomical wall of ventriculus|ventriculus anatomical wall serosa|serous membrane of wall of ventriculus|stomach wall serous membrane|wall of stomach serosa|serosa of stomach wall|serous membrane of gastric wall|serosa of stomach anatomical wall|gastric serosa|anatomical wall of stomach serosa|serous membrane of anatomical wall of stomach|serous membrane of wall of stomach|gastric wall serosa|serosa of ventriculus wall|ventriculus wall serous membrane|serous membrane of ventriculus anatomical wall|wall of ventriculus serosa|visceral peritoneum of stomach|serosa of anatomical wall of ventriculus|anatomical wall of ventriculus serous membrane|anatomical wall of ventriculus serosa|wall of ventriculus serous membrane|serosa of gastric wall|ventriculus wall serosa|serous membrane of stomach anatomical wall|gastric wall serous membrane|anatomical wall of stomach serous membrane|serosa of anatomical wall of stomach|wall of stomach serous membrane|stomach wall serosa|ventriculus anatomical wall serous membrane|tunica serosa gastricae|tunica serosa (gaster)|stomach serosa|stomach anatomical wall serous membrane|serosa of wall of ventriculus|serous membrane of stomach wall|stomach anatomical wall serosa|serosa of wall of stomach http://purl.obolibrary.org/obo/UBERON_0001201 UBERON:0001204 biolink:AnatomicalEntity mucosa of small intestine A mucosa that is part of a small intestine [Automatically generated definition]. go-plus.json mucous membrane of small bowel|mucosa of small bowel|tunica mucosa intestini tenuis|small bowel mucosa|mucosa of organ of small bowel|mucous membrane of small intestine|small intestinal mucosa|small intestine organ mucosa|mucosa of organ of small intestine|organ mucosa of small bowel|small bowel mucosa of organ|small bowel organ mucosa|small bowel mucous membrane|tunica mucosa (intestinum tenue)|small intestine mucosa of organ|organ mucosa of small intestine|small intestine mucosa|small intestine mucous membrane http://purl.obolibrary.org/obo/UBERON_0001204 CHEBI:73483 biolink:ChemicalSubstance grixazone B(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73483 chebi_ph7_3 CHEBI:73482 biolink:ChemicalSubstance grixazone A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73482 chebi_ph7_3 CHEBI:24439 biolink:ChemicalSubstance guanidinoacetic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_24439 UBERON:0001200 biolink:AnatomicalEntity submucosa of stomach the fibrous connective tissue layer beneath the stomach mucosa go-plus.json stomach submucosa|submucosa of ventriculus|tela submucosa gastricae|submucous layer of stomach|gastric submucosa|tela submucosa (gaster)|tela submucosa ventriculi|ventriculus submucosa http://purl.obolibrary.org/obo/UBERON_0001200 UBERON:4200172 biolink:AnatomicalEntity neck of humerus go-plus.json anatomic neck of humerus|collum anatomicum (Humerus)|collum anatomicum humeri|humeral neck http://purl.obolibrary.org/obo/UBERON_4200172 GO:0033249 biolink:BiologicalProcess positive regulation of penicillin catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json positive regulation of penicillin degradation|positive regulation of penicillin catabolism|positive regulation of penicillin breakdown http://purl.obolibrary.org/obo/GO_0033249 CHEBI:143788 biolink:ChemicalSubstance N(1)-(5-phospho-beta-D-ribosyl)glycinamide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_143788 chebi_ph7_3 GO:0008289 biolink:MolecularActivity lipid binding Binding to a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0008289 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_candida|goslim_agr|goslim_yeast|goslim_pir|goslim_plant|goslim_drosophila|goslim_generic GO:0008288 biolink:MolecularActivity boss receptor activity Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. go-plus.json sevenless receptor activity http://purl.obolibrary.org/obo/GO_0008288 GO:0008287 biolink:CellularComponent protein serine/threonine phosphatase complex A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0008287 goslim_pir GO:0008286 biolink:BiologicalProcess insulin receptor signaling pathway The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. go-plus.json daf-2 receptor signaling pathway|insulin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0008286 GO:0008285 biolink:BiologicalProcess negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. go-plus.json down-regulation of cell proliferation|negative regulation of cell proliferation|downregulation of cell proliferation|down regulation of cell proliferation|inhibition of cell proliferation http://purl.obolibrary.org/obo/GO_0008285 GO:0033240 biolink:BiologicalProcess positive regulation of cellular amine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. go-plus.json positive regulation of amine metabolism http://purl.obolibrary.org/obo/GO_0033240 GO:0008295 biolink:BiologicalProcess spermidine biosynthetic process The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. MetaCyc:POLYAMINSYN3-PWY|MetaCyc:BSUBPOLYAMSYN-PWY go-plus.json spermidine anabolism|spermidine synthesis|spermidine formation|spermidine biosynthesis http://purl.obolibrary.org/obo/GO_0008295 GO:0008294 biolink:MolecularActivity calcium- and calmodulin-responsive adenylate cyclase activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin. Reactome:R-HSA-111930|Reactome:R-HSA-442715 go-plus.json calcium/calmodulin-responsive adenylate cyclase activity|calcium- and calmodulin-responsive adenylyl cyclase activity http://purl.obolibrary.org/obo/GO_0008294 GO:0008293 biolink:BiologicalProcess torso signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json torso signalling pathway http://purl.obolibrary.org/obo/GO_0008293 GO:0008292 biolink:BiologicalProcess acetylcholine biosynthetic process The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline. go-plus.json acetylcholine anabolism|acetylcholine biosynthesis|acetylcholine synthesis|acetylcholine formation http://purl.obolibrary.org/obo/GO_0008292 GO:0008291 biolink:BiologicalProcess acetylcholine metabolic process The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. go-plus.json acetylcholine metabolism http://purl.obolibrary.org/obo/GO_0008291 GO:0008290 biolink:CellularComponent F-actin capping protein complex A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0008290 goslim_pir GO:0033248 biolink:BiologicalProcess negative regulation of penicillin catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json negative regulation of penicillin degradation|negative regulation of penicillin breakdown|negative regulation of penicillin catabolism http://purl.obolibrary.org/obo/GO_0033248 GO:0033247 biolink:BiologicalProcess regulation of penicillin catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json regulation of penicillin catabolism|regulation of penicillin degradation|regulation of penicillin breakdown http://purl.obolibrary.org/obo/GO_0033247 NCBITaxon:684364 biolink:OrganismalEntity Batrachochytrium dendrobatidis JAM81 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_684364 GO:0033246 biolink:BiologicalProcess positive regulation of penicillin metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json positive regulation of penicillin metabolism http://purl.obolibrary.org/obo/GO_0033246 GO:0033245 biolink:BiologicalProcess negative regulation of penicillin metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json negative regulation of penicillin metabolism http://purl.obolibrary.org/obo/GO_0033245 GO:0033244 biolink:BiologicalProcess regulation of penicillin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json regulation of penicillin metabolism http://purl.obolibrary.org/obo/GO_0033244 GO:0033243 biolink:BiologicalProcess positive regulation of cellular amine catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. go-plus.json positive regulation of amine breakdown|positive regulation of amine catabolism|positive regulation of amine degradation http://purl.obolibrary.org/obo/GO_0033243 GO:0033242 biolink:BiologicalProcess negative regulation of cellular amine catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. go-plus.json negative regulation of amine degradation|negative regulation of amine catabolism|negative regulation of amine breakdown http://purl.obolibrary.org/obo/GO_0033242 GO:0033241 biolink:BiologicalProcess regulation of cellular amine catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. go-plus.json regulation of amine catabolism|regulation of amine degradation|regulation of amine breakdown http://purl.obolibrary.org/obo/GO_0033241 GO:0033239 biolink:BiologicalProcess negative regulation of cellular amine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. go-plus.json negative regulation of amine metabolism http://purl.obolibrary.org/obo/GO_0033239 GO:0033238 biolink:BiologicalProcess regulation of cellular amine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. go-plus.json regulation of amine metabolism http://purl.obolibrary.org/obo/GO_0033238 GO:0008299 biolink:BiologicalProcess isoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. MetaCyc:POLYISOPRENSYN-PWY go-plus.json polyisoprenoid anabolism|polyisoprenoid synthesis|polyisoprenoid formation|isoprenoid anabolism|isoprenoid biosynthesis|polyterpene biosynthetic process|polyterpene biosynthesis|isoprenoid synthesis|isoprenoid formation|polyisoprenoid biosynthesis|polyisoprenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008299 GO:0008298 biolink:BiologicalProcess intracellular mRNA localization Any process in which mRNA is transported to, or maintained in, a specific location within the cell. go-plus.json establishment and maintenance of intracellular RNA localization|mRNA localization, intracellular|intracellular mRNA positioning|intracellular mRNA localisation|mRNA positioning, intracellular http://purl.obolibrary.org/obo/GO_0008298 GO:0008297 biolink:MolecularActivity single-stranded DNA exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule. go-plus.json ssDNA-specific exodeoxyribonuclease activity|single-stranded DNA specific exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0008297 GO:0008296 biolink:MolecularActivity 3'-5'-exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule. Reactome:R-HSA-9023943 go-plus.json 3'-5' exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0008296 GO:0033237 biolink:MolecularActivity obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+. go-plus.json 11beta-hydroxysteroid:NADP+ 11-oxidoreductase|corticosteroid 11-beta-dehydrogenase activity|beta-hydroxysteroid dehydrogenase|11-beta-hydroxysteroid dehydrogenase (NADP+) activity http://purl.obolibrary.org/obo/GO_0033237 GO:0033236 biolink:MolecularActivity obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+. go-plus.json 11-beta-hydroxysteroid dehydrogenase (NAD+) activity http://purl.obolibrary.org/obo/GO_0033236 GO:0033235 biolink:BiologicalProcess positive regulation of protein sumoylation Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein. go-plus.json positive regulation of sumoylation http://purl.obolibrary.org/obo/GO_0033235 GO:0033234 biolink:BiologicalProcess negative regulation of protein sumoylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein. go-plus.json negative regulation of sumoylation http://purl.obolibrary.org/obo/GO_0033234 GO:0033233 biolink:BiologicalProcess regulation of protein sumoylation Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein. go-plus.json regulation of sumoylation http://purl.obolibrary.org/obo/GO_0033233 GO:0033232 biolink:MolecularActivity ABC-type D-methionine transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out). RHEA:29779|EC:7.4.2.11 go-plus.json D-methionine-importing ATPase activity|D-methionine exporter|D-methionine-transporting ATPase activity|D-methionine transmembrane transporter activity|D-methionine transporter activity|ATP-dependent methionine transmembrane transporter activity|D-methionine-exporting ATPase activity|ATPase-coupled methionine transmembrane transporter activity|D-methionine importer|methionine transmembrane-transporting ATPase activity|ATP-dependent D-methionine transporter activity|ATPase-coupled D-methionine transporter activity http://purl.obolibrary.org/obo/GO_0033232 GO:0033231 biolink:BiologicalProcess carbohydrate export The directed movement of carbohydrates out of a cell or organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0033231 GO:0033230 biolink:MolecularActivity ABC-type cysteine transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out). go-plus.json ATPase-coupled cysteine transporter activity|cysteine-transporting ATPase activity|cysteine exporter|cysteine-exporting ATPase activity|ATP-dependent cysteine transporter activity|ATPase-coupled cysteine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0033230 GO:0033229 biolink:MolecularActivity cysteine transmembrane transporter activity Enables the transfer of cysteine from one side of a membrane to the other. RHEA:32795 go-plus.json http://purl.obolibrary.org/obo/GO_0033229 GO:0033228 biolink:BiologicalProcess cysteine export across plasma membrane The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json cysteine export http://purl.obolibrary.org/obo/GO_0033228 GO:0033227 biolink:BiologicalProcess dsRNA transport The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0033227 GO:0008269 biolink:MolecularActivity JAK pathway signal transduction adaptor activity The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way. go-plus.json http://purl.obolibrary.org/obo/GO_0008269 GO:0008268 biolink:MolecularActivity obsolete receptor signaling protein tyrosine kinase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json receptor signalling protein tyrosine kinase signalling protein activity|receptor signaling protein tyrosine kinase signaling protein activity http://purl.obolibrary.org/obo/GO_0008268 GO:0008267 biolink:MolecularActivity poly-glutamine tract binding Binding to a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0008267 GO:0008266 biolink:MolecularActivity poly(U) RNA binding Binding to a sequence of uracil residues in an RNA molecule. go-plus.json poly(U) binding http://purl.obolibrary.org/obo/GO_0008266 GO:0008265 biolink:MolecularActivity Mo-molybdopterin cofactor sulfurase activity Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase. EC:2.8.1.9|Reactome:R-HSA-947499 go-plus.json molybdopterin cofactor sulfurase activity|Mo-molybdopterin cofactor sulphurase activity|molybdopterin synthase sulfurylase activity http://purl.obolibrary.org/obo/GO_0008265 CHEBI:128120 biolink:ChemicalSubstance 19-(4-hydroxyphenyl)nonadecanoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_128120 GO:0008264 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008264 GO:0008263 biolink:MolecularActivity pyrimidine-specific mismatch base pair DNA N-glycosylase activity Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site. go-plus.json G/T-mismatch-specific thymine-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0008263 GO:0008273 biolink:MolecularActivity calcium, potassium:sodium antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in). Reactome:R-HSA-5625841|Reactome:R-HSA-5626356|Reactome:R-HSA-5626270|Reactome:R-HSA-425678|Reactome:R-HSA-5626316|Reactome:R-HSA-2514891 go-plus.json potassium-dependent sodium/calcium exchanger http://purl.obolibrary.org/obo/GO_0008273 GO:0008272 biolink:BiologicalProcess sulfate transport The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sulphate transport http://purl.obolibrary.org/obo/GO_0008272 GO:0008271 biolink:MolecularActivity secondary active sulfate transmembrane transporter activity Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json secondary active sulphate transmembrane transporter activity|sulfate porter activity|sulphate porter activity http://purl.obolibrary.org/obo/GO_0008271 GO:0008270 biolink:MolecularActivity zinc ion binding Binding to a zinc ion (Zn). go-plus.json Zn binding|zinc binding http://purl.obolibrary.org/obo/GO_0008270 GO:0033226 biolink:MolecularActivity 2-aminoethylphosphonate binding Binding to 2-aminoethylphosphonate. go-plus.json ciliatine binding|2-phosphonoethylamine binding http://purl.obolibrary.org/obo/GO_0033226 GO:0033225 biolink:MolecularActivity ATPase-coupled 2-aminoethylphosphonate transporter activity Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in). RHEA:32775 go-plus.json 2-aminoethylphosphonate transmembrane transporter activity|2-aminoethylphosphonate transporting ATPase activity|ATP-dependent 2-aminoethylphosphonate transporter activity|2-phosphonoethylamine transmembrane transporter activity|ciliatine transportingATPase activity|ciliatine transporter activity|2-phosphonoethylamine transporting ATPase activity|2-aminoethylphosphonate-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0033225 OBA:VT0004391 biolink:OntologyClass respiratory conducting tube morphology trait The morphology of a respiratory tube. go-plus.json morphology of respiratory tube http://purl.obolibrary.org/obo/OBA_VT0004391 GO:0033224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033224 GO:0033223 biolink:BiologicalProcess 2-aminoethylphosphonate transport The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json ciliatine transport|2-phosphonoethylamine transport http://purl.obolibrary.org/obo/GO_0033223 GO:0033222 biolink:MolecularActivity xylose binding Binding to the D- or L-enantiomer of xylose. go-plus.json http://purl.obolibrary.org/obo/GO_0033222 GO:0033221 biolink:MolecularActivity ATPase-coupled urea transmembrane transporter activity Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in). RHEA:32803 go-plus.json ATP-dependent urea transmembrane transporter activity|carbamide-transporting ATPase activity|urea-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0033221 GO:0033220 biolink:MolecularActivity obsolete ATPase-coupled amide-transporter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in). go-plus.json amide-transporting ATPase activity|ATP-dependent amide-transporter activity http://purl.obolibrary.org/obo/GO_0033220 GO:0033219 biolink:MolecularActivity urea binding Binding to urea, a water-soluble carboxamide with the structure H2N-CO-NH2. go-plus.json http://purl.obolibrary.org/obo/GO_0033219 GO:0033218 biolink:MolecularActivity amide binding Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. go-plus.json http://purl.obolibrary.org/obo/GO_0033218 goslim_pir GO:0033217 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter in response to iron ion starvation Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. go-plus.json regulation of transcription from RNA polymerase II promoter in response to iron deficiency http://purl.obolibrary.org/obo/GO_0033217 GO:0033216 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033216 GO:0008279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008279 GO:0008278 biolink:CellularComponent cohesin complex A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3). go-plus.json 14S cohesin|Smc1-Smc3 complex|cohesin core heterodimer|SMC complex|SMC/kleisin ring complex|9S cohesin http://purl.obolibrary.org/obo/GO_0008278 goslim_pir GO:0008277 biolink:BiologicalProcess regulation of G protein-coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. go-plus.json regulation of G protein coupled receptor protein signalling pathway|regulation of GPCR protein signalling pathway|regulation of G-protein coupled receptor protein signalling pathway|regulation of G-protein coupled receptor protein signaling pathway|regulation of GPCR protein signaling pathway|regulation of G-protein-coupled receptor protein signalling pathway|regulation of G protein coupled receptor protein signaling pathway http://purl.obolibrary.org/obo/GO_0008277 GO:0008276 biolink:MolecularActivity protein methyltransferase activity Catalysis of the transfer of a methyl group (CH3-) to a protein. Reactome:R-HSA-9632182 go-plus.json http://purl.obolibrary.org/obo/GO_0008276 GO:0008275 biolink:CellularComponent gamma-tubulin small complex A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex. go-plus.json gamma-tubulin small complex, mitotic spindle pole body|gamma-tubulin small complex, centrosomal|gammaTuSC|Tub4 complex|gamma-tubulin small complex, spindle pole body http://purl.obolibrary.org/obo/GO_0008275 GO:0008274 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008274 GO:0008284 biolink:BiologicalProcess positive regulation of cell population proliferation Any process that activates or increases the rate or extent of cell proliferation. go-plus.json activation of cell proliferation|up-regulation of cell proliferation|up regulation of cell proliferation|positive regulation of cell proliferation|upregulation of cell proliferation|stimulation of cell proliferation http://purl.obolibrary.org/obo/GO_0008284 NCBITaxon:1206795 biolink:OrganismalEntity Lophotrochozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1206795 GO:0008283 biolink:BiologicalProcess cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population. go-plus.json cell proliferation http://purl.obolibrary.org/obo/GO_0008283 goslim_chembl|goslim_mouse|goslim_agr|goslim_pir|goslim_drosophila|goslim_generic|goslim_flybase_ribbon NCBITaxon:1206794 biolink:OrganismalEntity Ecdysozoa go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1206794 GO:0008282 biolink:CellularComponent inward rectifying potassium channel A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity. go-plus.json Kir6.1-SUR complex|KCNJ8-SUR complex|Kir6-SUR complex|ATP-sensitive potassium channel complex|KCNJ11-SURx complex|KCNJ11-SUR complex|KCNJ8-SURx complex|Kir6.1-SURx complex|Kir6.2-SURx complex|inward rectifying K+ channel|Kir6.x complex|Kir6.x-SURx complex|Kir6.2-SUR complex http://purl.obolibrary.org/obo/GO_0008282 GO:0008281 biolink:MolecularActivity sulfonylurea receptor activity Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json sulphonylurea receptor activity http://purl.obolibrary.org/obo/GO_0008281 GO:0008280 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008280 GO:0033215 biolink:BiologicalProcess reductive iron assimilation A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins. go-plus.json iron assimilation by reduction and transport http://purl.obolibrary.org/obo/GO_0033215 GO:0033214 biolink:BiologicalProcess siderophore-dependent iron import into cell A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors. go-plus.json iron assimilation by capture and transport|iron chelate transport|iron assimilation by chelation and transport http://purl.obolibrary.org/obo/GO_0033214 GO:0033213 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033213 GO:0033212 biolink:BiologicalProcess iron import into cell The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. go-plus.json ferrous ion import|ferrous iron import|ferrous iron uptake|iron assimilation http://purl.obolibrary.org/obo/GO_0033212 GO:0033211 biolink:BiologicalProcess adiponectin-activated signaling pathway A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json adipocytokine signaling pathway|adiponectin-mediated signaling pathway|adiponectin-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0033211 GO:0033210 biolink:BiologicalProcess leptin-mediated signaling pathway A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. go-plus.json leptin-mediated signalling pathway|adipocytokine signaling pathway http://purl.obolibrary.org/obo/GO_0033210 GO:0033209 biolink:BiologicalProcess tumor necrosis factor-mediated signaling pathway A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json adipocytokine signaling pathway|TNF-alpha-mediated signaling pathway|tumor necrosis factor alpha-mediated signaling pathway|tumor necrosis factor-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0033209 GO:0033208 biolink:MolecularActivity UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide. go-plus.json UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity|Sda beta 1,4GalNAc transferase http://purl.obolibrary.org/obo/GO_0033208 GO:0033207 biolink:MolecularActivity beta-1,4-N-acetylgalactosaminyltransferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage. go-plus.json beta-1,4-GalNAc transferase activity http://purl.obolibrary.org/obo/GO_0033207 GO:0033206 biolink:BiologicalProcess meiotic cytokinesis A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells. go-plus.json cytokinesis after meiosis http://purl.obolibrary.org/obo/GO_0033206 GO:0033205 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033205 GO:0008249 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008249 GO:0008248 biolink:MolecularActivity obsolete pre-mRNA splicing factor activity OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA. go-plus.json pre-mRNA splicing factor activity http://purl.obolibrary.org/obo/GO_0008248 GO:0008247 biolink:CellularComponent 1-alkyl-2-acetylglycerophosphocholine esterase complex An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF). go-plus.json platelet-activating factor acetylhydrolase complex|2-acetyl-1-alkylglycerophosphocholine esterase complex http://purl.obolibrary.org/obo/GO_0008247 GO:0008246 biolink:MolecularActivity obsolete electron transfer flavoprotein OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system. go-plus.json ETF|electron transfer flavoprotein http://purl.obolibrary.org/obo/GO_0008246 GO:0008245 biolink:CellularComponent obsolete lysosomal membrane hydrogen-transporting ATPase OBSOLETE. (Was not defined before being made obsolete). go-plus.json lysosomal membrane hydrogen-transporting ATPase|V-ATPase http://purl.obolibrary.org/obo/GO_0008245 GO:0008244 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008244 GO:0008243 biolink:MolecularActivity obsolete plasminogen activator activity OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin. go-plus.json abbokinase activity|urinary esterase A|tissue plasminogen activator activity|urokinase activity|plasminogen activator activity|urinary plasminogen activator activity|t-plasminogen activator activity|u-plasminogen activator activity|cellular plasminogen activator activity|tPA activity|plasminogen activator, tissue-type|tissue-type plasminogen activator activity|urokinase plasminogen activator|urokinase-type plasminogen activator|two-chain urokinase-type plasminogen activator|t-PA|u-PA|double-chain urokinase-type plasminogen activator|uPA http://purl.obolibrary.org/obo/GO_0008243 GO:0008242 biolink:MolecularActivity omega peptidase activity Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes. MetaCyc:3.4.19.9-RXN|EC:3.4.19.-|EC:3.4.19.9|MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN|EC:3.4.19.2 go-plus.json peptidase activity, acting on peptides containing modified amino acids http://purl.obolibrary.org/obo/GO_0008242 GO:0008241 biolink:MolecularActivity peptidyl-dipeptidase activity Catalysis of the release of C-terminal dipeptides from a polypeptide chain. EC:3.4.15.- go-plus.json http://purl.obolibrary.org/obo/GO_0008241 GO:0008251 biolink:MolecularActivity tRNA-specific adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule. Reactome:R-HSA-6782336|Reactome:R-HSA-6782311 go-plus.json tRNA-adenosine deaminase activity http://purl.obolibrary.org/obo/GO_0008251 GO:0008250 biolink:CellularComponent oligosaccharyltransferase complex A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected. go-plus.json oligosaccharyl transferase complex|OST complex http://purl.obolibrary.org/obo/GO_0008250 GO:0033204 biolink:MolecularActivity ribonuclease P RNA binding Binding to RNA subunit of ribonuclease P. go-plus.json RNase P RNA binding http://purl.obolibrary.org/obo/GO_0033204 GO:0033203 biolink:CellularComponent DNA helicase A complex A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction. go-plus.json http://purl.obolibrary.org/obo/GO_0033203 GO:0033202 biolink:CellularComponent DNA helicase complex A protein complex that possesses DNA helicase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0033202 goslim_pir|goslim_metagenomics GO:0033201 biolink:MolecularActivity alpha-1,4-glucan synthase activity Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP. RHEA:18189|EC:2.4.1.21 go-plus.json 1,4-alpha-glucan synthase activity http://purl.obolibrary.org/obo/GO_0033201 GO:0033200 biolink:MolecularActivity inositol heptakisphosphate 5-kinase activity Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate. go-plus.json IP7 5-kinase activity|diphosphoinositol-pentakisphosphate 5-kinase activity http://purl.obolibrary.org/obo/GO_0033200 GO:0008259 biolink:BiologicalProcess obsolete transforming growth factor beta ligand binding to type I receptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json TGF-beta ligand binding to type I receptor|TGFbeta ligand binding to type I receptor|transforming growth factor beta ligand binding to type I receptor http://purl.obolibrary.org/obo/GO_0008259 GO:0008258 biolink:BiologicalProcess head involution Movement of the anterior ectoderm to the interior of the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0008258 GO:0008257 biolink:MolecularActivity protein histidine tele-kinase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine. MetaCyc:2.7.13.2-RXN|EC:2.7.13.2|RHEA:11860 go-plus.json protein-histidine tele-kinase activity|HK3|ATP:protein-L-histidine N-tele-phosphotransferase activity|ATP:protein-L-histidine Ntau-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008257 GO:0008256 biolink:MolecularActivity protein histidine pros-kinase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine. MetaCyc:2.7.13.1-RXN|EC:2.7.13.1|RHEA:22720 go-plus.json HK2|protein-histidine pros-kinase activity|ATP:protein-L-histidine N-pros-phosphotransferase activity|ATP:protein-L-histidine Npi-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008256 GO:0008255 biolink:MolecularActivity ecdysis-triggering hormone activity The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0008255 GO:0008254 biolink:MolecularActivity 3'-nucleotidase activity Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate. EC:3.1.3.6|MetaCyc:3-NUCLEOTID-RXN|RHEA:10144 go-plus.json 3'-ribonucleotide phosphohydrolase activity|3' nucleotidase activity|3'-phosphatase activity|3'-mononucleotidase activity|3'-ribonucleotidase activity http://purl.obolibrary.org/obo/GO_0008254 CHEBI:104120 biolink:ChemicalSubstance alpha-methylene gamma-butyrolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_104120 chebi_ph7_3 GO:0008253 biolink:MolecularActivity 5'-nucleotidase activity Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. RHEA:12484|MetaCyc:5-NUCLEOTID-RXN|EC:3.1.3.5|Reactome:R-HSA-109291|Reactome:R-HSA-109278|Reactome:R-HSA-109514|Reactome:R-HSA-109387|Reactome:R-HSA-109480|Reactome:R-HSA-109449|Reactome:R-HSA-8940074|Reactome:R-HSA-109470|Reactome:R-HSA-74248|Reactome:R-HSA-5694126|Reactome:R-HSA-109415|Reactome:R-HSA-8940070|Reactome:R-HSA-109380 go-plus.json AMP phosphohydrolase|5'-ribonucleotide phosphohydrolase activity|snake venom 5'-nucleotidase|thimidine monophosphate nucleotidase|5'-AMP nucleotidase|5' nucleotidase activity|AMP phosphatase|AMPase|5'-AMPase|5'-mononucleotidase activity|adenosine 5'-phosphatase|uridine 5'-nucleotidase|5'-adenylic phosphatase|UMPase|adenosine monophosphatase http://purl.obolibrary.org/obo/GO_0008253 GO:0008252 biolink:MolecularActivity nucleotidase activity Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate. RHEA:22140|MetaCyc:NUCLEOTIDASE-RXN go-plus.json nucleotide phosphohydrolase activity|deoxyinosine-activated nucleotidase (DIAN)|deoxyribonucleoside-activated nucleotidase (DAN)|NSP II|NSP I|nucleotide-specific phosphatase activity|acid nucleotidase activity http://purl.obolibrary.org/obo/GO_0008252 GO:0008262 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008262 GO:0008261 biolink:MolecularActivity allatostatin receptor activity Combining with allatostatin to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0008261 GO:0008260 biolink:MolecularActivity 3-oxoacid CoA-transferase activity Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA. EC:2.8.3.5|Reactome:R-HSA-74177|RHEA:25480|MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN go-plus.json 3-oxo-CoA transferase activity|3-ketoacid CoA-transferase activity|3-oxoacid coenzyme A-transferase activity|succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity|acetoacetyl coenzyme A-succinic thiophorase activity|succinyl-CoA:3-oxo-acid CoA-transferase activity|acetoacetate succinyl-CoA transferase activity|3-ketoacid coenzyme A transferase activity|succinyl-CoA transferase activity|3-oxoacid CoA dehydrogenase activity|succinyl-CoA:3-ketoacid-CoA transferase activity http://purl.obolibrary.org/obo/GO_0008260 GO:0008229 biolink:MolecularActivity obsolete opsonin activity OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis. go-plus.json opsonin activity http://purl.obolibrary.org/obo/GO_0008229 GO:0008228 biolink:BiologicalProcess opsonization The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody. Wikipedia:Opsonin go-plus.json http://purl.obolibrary.org/obo/GO_0008228 GO:0008227 biolink:MolecularActivity G protein-coupled amine receptor activity Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json amine receptor activity, G-protein coupled|biogenic amine receptor|G-protein coupled amine receptor activity http://purl.obolibrary.org/obo/GO_0008227 GO:0008226 biolink:MolecularActivity tyramine receptor activity Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine. go-plus.json http://purl.obolibrary.org/obo/GO_0008226 CHEBI:48470 biolink:ChemicalSubstance amidobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48470 GO:0008225 biolink:MolecularActivity obsolete Gram-negative antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, Gram-negative bacterial cells. go-plus.json Gram-negative antibacterial peptide activity http://purl.obolibrary.org/obo/GO_0008225 GO:0008224 biolink:MolecularActivity obsolete Gram-positive antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, Gram-positive bacterial cells. go-plus.json Gram-positive antibacterial peptide activity http://purl.obolibrary.org/obo/GO_0008224 GO:0008223 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008223 GO:0008222 biolink:MolecularActivity obsolete tumor antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json tumor antigen http://purl.obolibrary.org/obo/GO_0008222 CHEBI:48474 biolink:ChemicalSubstance (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_48474 GO:0008221 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008221 GO:0008220 biolink:BiologicalProcess obsolete necrosis OBSOLETE. The processes that cause necrosis, the death of tissues, in another organism. go-plus.json necrosis http://purl.obolibrary.org/obo/GO_0008220 CHEBI:48467 biolink:ChemicalSubstance (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48467 CHEBI:48469 biolink:ChemicalSubstance pyrimidinimine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48469 GO:0008239 biolink:MolecularActivity dipeptidyl-peptidase activity Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain. MetaCyc:3.4.14.11-RXN|EC:3.4.14.11|EC:3.4.14.5|EC:3.4.14.4|EC:3.4.14.2|EC:3.4.14.1|MetaCyc:3.4.14.4-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008239 GO:0008238 biolink:MolecularActivity exopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both. go-plus.json exoprotease activity http://purl.obolibrary.org/obo/GO_0008238 GO:0008237 biolink:MolecularActivity metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Reactome:R-HSA-9013284|Reactome:R-HSA-193679|Reactome:R-HSA-2220944|Reactome:R-HSA-157629|Reactome:R-HSA-9604264|Reactome:R-HSA-2220976|Reactome:R-HSA-2022396|Reactome:R-HSA-157632|Reactome:R-HSA-5211405|Reactome:R-HSA-8986181|Reactome:R-HSA-2730752|Reactome:R-HSA-3928660|Reactome:R-HSA-2666278|Reactome:R-HSA-9662837|Reactome:R-HSA-5211387|Reactome:R-HSA-2022399|Reactome:R-HSA-2022393|Reactome:R-HSA-5211400|Reactome:R-HSA-5211356|Reactome:R-HSA-2022368|Reactome:R-HSA-5211391|Reactome:R-HSA-5211340 go-plus.json metalloproteinase activity|metalloprotease activity http://purl.obolibrary.org/obo/GO_0008237 GO:0047801 biolink:MolecularActivity L-cysteine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate. MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN|EC:2.6.1.3|Reactome:R-HSA-9012597|RHEA:17441 go-plus.json L-cysteine aminotransferase activity|CGT|cysteine aminotransferase activity|cysteine transaminase activity http://purl.obolibrary.org/obo/GO_0047801 GO:0047800 biolink:MolecularActivity cysteamine dioxygenase activity Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine. MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN|RHEA:14409|KEGG_REACTION:R02467|EC:1.13.11.19|Reactome:R-HSA-6814153 go-plus.json persulfurase activity|cysteamine:oxygen oxidoreductase activity|2-aminoethanethiol:oxygen oxidoreductase activity|cysteamine oxygenase activity http://purl.obolibrary.org/obo/GO_0047800 GO:0008236 biolink:MolecularActivity serine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). Reactome:R-HSA-6801766|Reactome:R-HSA-1461993|Reactome:R-HSA-2022383|Reactome:R-HSA-3132753 go-plus.json serine protease activity http://purl.obolibrary.org/obo/GO_0008236 GO:0008235 biolink:MolecularActivity metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. go-plus.json http://purl.obolibrary.org/obo/GO_0008235 GO:0008234 biolink:MolecularActivity cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. Reactome:R-HSA-5660752|Reactome:R-HSA-2467775|Reactome:R-HSA-2022381|Reactome:R-HSA-2467809 go-plus.json thiol protease activity|cysteine protease activity http://purl.obolibrary.org/obo/GO_0008234 GO:0008233 biolink:MolecularActivity peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. Reactome:R-HSA-3065959|Reactome:R-HSA-6803060|Reactome:R-HSA-5685902|Reactome:R-HSA-376149|Reactome:R-HSA-5684864|Reactome:R-HSA-3139027|Reactome:R-HSA-4167501|EC:3.4.-.-|Reactome:R-HSA-5655483|Reactome:R-HSA-5693319|Reactome:R-HSA-3000243|Reactome:R-HSA-448678|Reactome:R-HSA-205112|Reactome:R-HSA-3065958 go-plus.json peptidase activity, acting on D-amino acid peptides|peptide hydrolase activity|hydrolase, acting on peptide bonds|proteinase activity|protease activity|peptidase activity, acting on L-amino acid peptides http://purl.obolibrary.org/obo/GO_0008233 goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida CHEBI:2807 biolink:ChemicalSubstance arbutin 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_2807 GO:0008232 biolink:CellularComponent activator ecdysone receptor complex A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes. go-plus.json activator ecdysone receptor holocomplex http://purl.obolibrary.org/obo/GO_0008232 CHEBI:48462 biolink:ChemicalSubstance 5-deoxy-alpha-D-ribose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48462 GO:0008231 biolink:CellularComponent repressor ecdysone receptor complex A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes. go-plus.json repressor ecdysone receptor holocomplex http://purl.obolibrary.org/obo/GO_0008231 GO:0008230 biolink:CellularComponent ecdysone receptor holocomplex A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes. go-plus.json http://purl.obolibrary.org/obo/GO_0008230 GO:0047809 biolink:MolecularActivity D-2-hydroxy-acid dehydrogenase activity Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate. EC:1.1.99.6|MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN|KEGG_REACTION:R00297|RHEA:15089 go-plus.json (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity|2-hydroxy acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047809 GO:0008240 biolink:MolecularActivity tripeptidyl-peptidase activity Catalysis of the release of an N-terminal tripeptide from a polypeptide. MetaCyc:3.4.14.9-RXN|EC:3.4.14.9|MetaCyc:3.4.14.10-RXN|EC:3.4.14.10 go-plus.json http://purl.obolibrary.org/obo/GO_0008240 GO:0047808 biolink:MolecularActivity D(-)-tartrate dehydratase activity Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate. MetaCyc:D--TARTRATE-DEHYDRATASE-RXN|KEGG_REACTION:R00340|EC:4.2.1.81|RHEA:18289 go-plus.json D-tartrate dehydratase activity|(S,S)-tartrate hydro-lyase activity|(S,S)-tartrate hydro-lyase (oxaloacetate-forming) http://purl.obolibrary.org/obo/GO_0047808 GO:0047807 biolink:MolecularActivity cytokinin 7-beta-glucosyltransferase activity Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event. MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.118|RHEA:23272|KEGG_REACTION:R04071 go-plus.json UDP-glucose-zeatin 7-glucosyltransferase activity|UDPglucose:zeatin 7-glucosyltransferase activity|UDP-glucose:zeatin 7-glucosyltransferase activity|cytokinin 7-b-glucosyltransferase activity|uridine diphosphoglucose-zeatin 7-glucosyltransferase activity|cytokinin 7-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047807 GO:0047806 biolink:MolecularActivity cytochrome-c3 hydrogenase activity Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3. RHEA:20625|UM-BBD_enzymeID:e0481|EC:1.12.2.1|MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN go-plus.json cytochrome c3 reductase activity|cytochrome hydrogenase activity|H2:ferricytochrome c3 oxidoreductase activity|hydrogen:ferricytochrome-c3 oxidoreductase activity|H(2):ferricytochrome c3 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047806 GO:0047805 biolink:MolecularActivity cytidylate cyclase activity Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+). MetaCyc:CYTIDYLATE-CYCLASE-RXN|RHEA:14737|KEGG_REACTION:R00574|EC:4.6.1.6 go-plus.json cytidylyl cyclase activity|3'5'-cyclic-CMP synthase activity|CTP diphosphate-lyase (cyclizing)|cytidyl cyclase activity|3',5'-cyclic-CMP synthase activity|CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming) http://purl.obolibrary.org/obo/GO_0047805 GO:0047804 biolink:MolecularActivity cysteine-S-conjugate beta-lyase activity Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate. MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN|EC:4.4.1.13|RHEA:18121 go-plus.json cysteine-S-conjugate b-lyase activity|cysteine conjugate beta-lyase activity|L-cysteine-S-conjugate thiol-lyase (deaminating) activity|glutamine transaminase K/cysteine conjugate beta-lyase activity|L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming) http://purl.obolibrary.org/obo/GO_0047804 GO:0047803 biolink:MolecularActivity cysteine lyase activity Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide. RHEA:20916|MetaCyc:CYSTEINE-LYASE-RXN|EC:4.4.1.10 go-plus.json L-cysteine hydrogen-sulfide-lyase (adding sulfite)|cysteine (sulfite) lyase activity|L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming) http://purl.obolibrary.org/obo/GO_0047803 GO:0047802 biolink:MolecularActivity cysteine-conjugate transaminase activity Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate. MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN|KEGG_REACTION:R04338|EC:2.6.1.75|RHEA:13485 go-plus.json cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)|cysteine conjugate aminotransferase activity|S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047802 OBA:1000078 biolink:OntologyClass attribute of organelle The quality of a organelle. go-plus.json organelle quality trait|quality of organelle http://purl.obolibrary.org/obo/OBA_1000078 GO:0033196 biolink:MolecularActivity tryparedoxin peroxidase activity Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O. MetaCyc:1.11.1.15-RXN go-plus.json TXNPx activity http://purl.obolibrary.org/obo/GO_0033196 GO:0033195 biolink:BiologicalProcess response to alkyl hydroperoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0033195 GO:0033194 biolink:BiologicalProcess response to hydroperoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH. go-plus.json http://purl.obolibrary.org/obo/GO_0033194 NCBITaxon:273057 biolink:OrganismalEntity Saccharolobus solfataricus P2 go-plus.json Sulfolobus solfataricus P2 http://purl.obolibrary.org/obo/NCBITaxon_273057 GO:0033193 biolink:CellularComponent Lsd1/2 complex A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast. go-plus.json SAPHIRE complex|Swm complex|Swm1/2 complex http://purl.obolibrary.org/obo/GO_0033193 GO:0033192 biolink:MolecularActivity calmodulin-dependent protein phosphatase activity Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin. Reactome:R-HSA-2730849|Reactome:R-HSA-4551451 go-plus.json calcineurin activity|calcium/calmodulin-dependent protein phosphatase activity|calcium- and calmodulin-dependent protein phosphatase activity|Ca2+/CaM-dependent protein phosphatase activity http://purl.obolibrary.org/obo/GO_0033192 GO:0033191 biolink:MolecularActivity macrophomate synthase activity Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate. go-plus.json http://purl.obolibrary.org/obo/GO_0033191 GO:0033190 biolink:MolecularActivity solanapyrone synthase activity Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A. go-plus.json http://purl.obolibrary.org/obo/GO_0033190 OBA:1000076 biolink:OntologyClass attribute of cell The quality of a cell. go-plus.json cell quality trait|quality of cell http://purl.obolibrary.org/obo/OBA_1000076 GO:0033199 biolink:MolecularActivity obsolete inositol heptakisphosphate 4-kinase or 6-kinase activity OBSOLETE. Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate. go-plus.json inositol heptakisphosphate 4-kinase or 6-kinase activity http://purl.obolibrary.org/obo/GO_0033199 GO:0033198 biolink:BiologicalProcess response to ATP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. go-plus.json response to adenosine triphosphate|response to adenosine 5'-triphosphate http://purl.obolibrary.org/obo/GO_0033198 GO:0033197 biolink:BiologicalProcess response to vitamin E Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus. go-plus.json response to O-Acetyl-alpha-tocopherol|response to DL-alpha-tocopherol acetate|response to DL-alpha-tocopheryl acetate http://purl.obolibrary.org/obo/GO_0033197 GO:0033185 biolink:CellularComponent dolichol-phosphate-mannose synthase complex A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively. go-plus.json dolichyl-phosphate beta-D-mannosyltransferase complex|DPM synthase complex http://purl.obolibrary.org/obo/GO_0033185 GO:0033184 biolink:BiologicalProcess positive regulation of histone ubiquitination Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0033184 GO:0033183 biolink:BiologicalProcess negative regulation of histone ubiquitination Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0033183 GO:0033182 biolink:BiologicalProcess regulation of histone ubiquitination Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein. go-plus.json http://purl.obolibrary.org/obo/GO_0033182 GO:0033181 biolink:CellularComponent plasma membrane proton-transporting V-type ATPase complex A proton-transporting two-sector ATPase complex found in the plasma membrane. go-plus.json plasma membrane hydrogen ion-transporting ATPase http://purl.obolibrary.org/obo/GO_0033181 GO:0033180 biolink:CellularComponent proton-transporting V-type ATPase, V1 domain A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A. go-plus.json http://purl.obolibrary.org/obo/GO_0033180 GO:0033189 biolink:BiologicalProcess response to vitamin A Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus. go-plus.json response to retinol http://purl.obolibrary.org/obo/GO_0033189 GO:0033188 biolink:MolecularActivity sphingomyelin synthase activity Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin. MetaCyc:2.7.8.27-RXN|KEGG_REACTION:R08969|Reactome:R-HSA-429798|Reactome:R-HSA-429786|EC:2.7.8.27|RHEA:18765 go-plus.json SMS2|SMS1|SM synthase activity|ceramide:phosphatidylcholine cholinephosphotransferase activity|phosphatidylcholine:ceramide cholinephosphotransferase activity http://purl.obolibrary.org/obo/GO_0033188 GO:0033187 biolink:MolecularActivity obsolete inositol hexakisphosphate 4-kinase or 6-kinase activity OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate. go-plus.json inositol hexakisphosphate 4-kinase or 6-kinase activity http://purl.obolibrary.org/obo/GO_0033187 GO:0033186 biolink:CellularComponent CAF-1 complex A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48. go-plus.json chromatin assembly factor 1 complex http://purl.obolibrary.org/obo/GO_0033186 GO:0033174 biolink:CellularComponent chloroplast proton-transporting ATP synthase complex, catalytic core CF(1) The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits. go-plus.json chloroplast proton-transporting F-type ATPase complex, catalytic core CF(1) http://purl.obolibrary.org/obo/GO_0033174 GO:0033173 biolink:BiologicalProcess calcineurin-NFAT signaling cascade Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+). go-plus.json calcineurin-NFAT signaling pathway|calcineurin-NFAT signalling pathway http://purl.obolibrary.org/obo/GO_0033173 GO:0033172 biolink:CellularComponent gas vesicle shell The proteinaceous structure surrounding a gas vesicle. go-plus.json gas vesicle membrane|gas vesicle wall http://purl.obolibrary.org/obo/GO_0033172 GO:0033171 biolink:MolecularActivity obsolete nucleoprotein filament-forming ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament. go-plus.json nucleoprotein filament-forming ATPase activity http://purl.obolibrary.org/obo/GO_0033171 GO:0033170 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033170 GO:0033179 biolink:CellularComponent proton-transporting V-type ATPase, V0 domain A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring. go-plus.json http://purl.obolibrary.org/obo/GO_0033179 GO:0033178 biolink:CellularComponent proton-transporting two-sector ATPase complex, catalytic domain A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled. go-plus.json http://purl.obolibrary.org/obo/GO_0033178 GO:0033177 biolink:CellularComponent proton-transporting two-sector ATPase complex, proton-transporting domain A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0033177 GO:0033176 biolink:CellularComponent proton-transporting V-type ATPase complex A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. go-plus.json hydrogen-translocating V-type ATPase complex http://purl.obolibrary.org/obo/GO_0033176 GO:0033175 biolink:CellularComponent chloroplast proton-transporting ATP synthase complex, coupling factor CF(o) All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins. go-plus.json chloroplast proton-transporting ATP synthase complex, coupling factor CF(0)|chloroplast proton-transporting F-type ATPase complex, coupling factor CF(o) http://purl.obolibrary.org/obo/GO_0033175 GO:0033163 biolink:CellularComponent microneme membrane The lipid bilayer surrounding a microneme. go-plus.json http://purl.obolibrary.org/obo/GO_0033163 GO:0033162 biolink:CellularComponent melanosome membrane The lipid bilayer surrounding a melanosome. go-plus.json http://purl.obolibrary.org/obo/GO_0033162 GO:0033161 biolink:MolecularActivity mitogen-activated protein kinase kinase kinase kinase binding Binding to a mitogen-activated protein kinase kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase kinase. go-plus.json MAPKKKK binding http://purl.obolibrary.org/obo/GO_0033161 GO:0033160 biolink:BiologicalProcess obsolete positive regulation of protein import into nucleus, translocation OBSOLETE. Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. go-plus.json positive regulation of protein import into cell nucleus, translocation http://purl.obolibrary.org/obo/GO_0033160 GO:0033169 biolink:BiologicalProcess histone H3-K9 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0033169 GO:0033168 biolink:BiologicalProcess conversion of ds siRNA to ss siRNA involved in RNA interference The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference. go-plus.json RNA interference, conversion of ds siRNA to ss siRNA http://purl.obolibrary.org/obo/GO_0033168 GO:0033167 biolink:CellularComponent ARC complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA. go-plus.json argonaute siRNA chaperone complex http://purl.obolibrary.org/obo/GO_0033167 GO:0033166 biolink:CellularComponent hyaline layer A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms. go-plus.json http://purl.obolibrary.org/obo/GO_0033166 GO:0033165 biolink:CellularComponent interphotoreceptor matrix A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_0033165 GO:0033164 biolink:MolecularActivity glycolipid 1,6-alpha-mannosyltransferase activity Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage. EC:2.4.1.232|MetaCyc:2.4.1.232-RXN go-plus.json GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity|GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity|initiation-specific alpha-1,6-mannosyltransferase activity|GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity|glycolipid 6-alpha-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0033164 GO:0033152 biolink:BiologicalProcess immunoglobulin V(D)J recombination The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. go-plus.json immunoglobulin V-D-J joining|immunoglobulin V-J recombination|immunoglobulin V-J joining|immunoglobulin V(D)J joining|immunoglobulin V-D-J recombination http://purl.obolibrary.org/obo/GO_0033152 GO:0033151 biolink:BiologicalProcess V(D)J recombination The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). Wikipedia:V(D)J_recombination go-plus.json V-J recombination|V-J joining|V(D)J joining|V-D-J recombination|V-D-J joining http://purl.obolibrary.org/obo/GO_0033151 GO:0033150 biolink:CellularComponent cytoskeletal calyx A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0033150 GO:0033159 biolink:BiologicalProcess obsolete negative regulation of protein import into nucleus, translocation OBSOLETE. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. go-plus.json negative regulation of protein import into cell nucleus, translocation http://purl.obolibrary.org/obo/GO_0033159 GO:0033158 biolink:BiologicalProcess obsolete regulation of protein import into nucleus, translocation OBSOLETE. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. go-plus.json regulation of protein import into cell nucleus, translocation http://purl.obolibrary.org/obo/GO_0033158 GO:0033157 biolink:BiologicalProcess regulation of intracellular protein transport Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0033157 GO:0033156 biolink:BiologicalProcess oligogalacturonide transport The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0033156 GO:0033155 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033155 GO:0033154 biolink:MolecularActivity ABC-type oligogalacturonide transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in). TC:3.A.1.1.11 go-plus.json oligogalacturonide transporting ATPase activity|ATP-dependent oligogalacturonide transmembrane transporter activity|ATPase-coupled oligogalacturonide transmembrane transporter activity|oligogalacturonide transmembrane transporter activity|oligogalacturonide-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0033154 GO:0033153 biolink:BiologicalProcess T cell receptor V(D)J recombination The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). go-plus.json T cell receptor V-J recombination|T cell receptor V-J joining|T cell receptor V-D-J recombination|T cell receptor V(D)J joining|T cell receptor V-D-J joining|TCR V(D)J recombination|T-cell receptor V(D)J recombination http://purl.obolibrary.org/obo/GO_0033153 GO:0008189 biolink:MolecularActivity obsolete apoptosis inhibitor activity OBSOLETE. The function held by products which directly block any step in the process of apoptosis. go-plus.json apoptosis inhibitor activity http://purl.obolibrary.org/obo/GO_0008189 GO:0008188 biolink:MolecularActivity neuropeptide receptor activity Combining with a neuropeptide to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0008188 GO:0008187 biolink:MolecularActivity poly-pyrimidine tract binding Binding to a stretch of pyrimidines (cytosine or uracil) in an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0008187 GO:0008186 biolink:MolecularActivity ATP-dependent activity, acting on RNA Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. go-plus.json RNA-dependent ATPase activity|ATPase, acting on RNA|ATPase activity, acting on RNA|RNA-dependent adenosinetriphosphatase activity http://purl.obolibrary.org/obo/GO_0008186 GO:0033141 biolink:BiologicalProcess positive regulation of peptidyl-serine phosphorylation of STAT protein Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json activation of serine phosphorylation of STAT3 protein|up-regulation of serine phosphorylation of STAT3 protein|positive regulation of serine phosphorylation of STAT3 protein|upregulation of serine phosphorylation of STAT3 protein|up regulation of serine phosphorylation of STAT3 protein http://purl.obolibrary.org/obo/GO_0033141 GO:0008196 biolink:MolecularActivity vitellogenin receptor activity Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0008196 GO:0008195 biolink:MolecularActivity phosphatidate phosphatase activity Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate. Reactome:R-HSA-1483203|Reactome:R-HSA-6797630|Reactome:R-HSA-5221130|EC:3.1.3.4|Reactome:R-HSA-163750|Reactome:R-HSA-163688|Reactome:R-HSA-164056|Reactome:R-HSA-163689|Reactome:R-HSA-2029468|MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN|Reactome:R-HSA-75899|Reactome:R-HSA-390329|RHEA:27429 go-plus.json phosphatidic acid phosphatase activity|phosphatidate phosphohydrolase activity|phosphatic acid phosphohydrolase activity|acid phosphatidyl phosphatase activity|3-sn-phosphatidate phosphohydrolase activity|phosphatic acid phosphatase activity http://purl.obolibrary.org/obo/GO_0008195 GO:0033140 biolink:BiologicalProcess negative regulation of peptidyl-serine phosphorylation of STAT protein Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json down-regulation of serine phosphorylation of STAT3 protein|inhibition of serine phosphorylation of STAT3 protein|negative regulation of serine phosphorylation of STAT3 protein|down regulation of serine phosphorylation of STAT3 protein|downregulation of serine phosphorylation of STAT3 protein http://purl.obolibrary.org/obo/GO_0033140 GO:0008194 biolink:MolecularActivity UDP-glycosyltransferase activity Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. Reactome:R-HSA-162730 go-plus.json http://purl.obolibrary.org/obo/GO_0008194 GO:0008193 biolink:MolecularActivity tRNA guanylyltransferase activity Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs. EC:2.7.7.79|RHEA:54564 go-plus.json http://purl.obolibrary.org/obo/GO_0008193 GO:0008192 biolink:MolecularActivity RNA guanylyltransferase activity Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0008192 CARO:0030000 biolink:OntologyClass biological entity go-plus.json http://purl.obolibrary.org/obo/CARO_0030000 GO:0008191 biolink:MolecularActivity metalloendopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity. go-plus.json metalloproteinase inhibitor|metalloprotease inhibitor http://purl.obolibrary.org/obo/GO_0008191 GO:0008190 biolink:MolecularActivity eukaryotic initiation factor 4E binding Binding to eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation. go-plus.json eIF4E binding http://purl.obolibrary.org/obo/GO_0008190 GO:0033149 biolink:MolecularActivity FFAT motif binding Binding to a FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family. go-plus.json http://purl.obolibrary.org/obo/GO_0033149 GO:0033148 biolink:BiologicalProcess positive regulation of intracellular estrogen receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. go-plus.json positive regulation of estrogen receptor signalling pathway|positive regulation of estrogen receptor signaling pathway http://purl.obolibrary.org/obo/GO_0033148 GO:0033147 biolink:BiologicalProcess negative regulation of intracellular estrogen receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. go-plus.json negative regulation of estrogen receptor signaling pathway|negative regulation of estrogen receptor signalling pathway http://purl.obolibrary.org/obo/GO_0033147 GO:0033146 biolink:BiologicalProcess regulation of intracellular estrogen receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. go-plus.json regulation of estrogen receptor signalling pathway|regulation of estrogen receptor signaling pathway http://purl.obolibrary.org/obo/GO_0033146 GO:0033145 biolink:BiologicalProcess positive regulation of intracellular steroid hormone receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. go-plus.json positive regulation of steroid hormone receptor signalling pathway|positive regulation of steroid hormone receptor signaling pathway http://purl.obolibrary.org/obo/GO_0033145 GO:0033144 biolink:BiologicalProcess negative regulation of intracellular steroid hormone receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. go-plus.json negative regulation of steroid hormone receptor signaling pathway|negative regulation of steroid hormone receptor signalling pathway http://purl.obolibrary.org/obo/GO_0033144 GO:0033143 biolink:BiologicalProcess regulation of intracellular steroid hormone receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. go-plus.json regulation of steroid hormone receptor signaling pathway|regulation of steroid hormone receptor signalling pathway http://purl.obolibrary.org/obo/GO_0033143 GO:0033142 biolink:MolecularActivity progesterone receptor binding Binding to a progesterone receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0033142 OBA:1000099 biolink:OntologyClass appendage trait The quality of a appendage. go-plus.json quality of appendage|appendage quality trait http://purl.obolibrary.org/obo/OBA_1000099 GO:0033139 biolink:BiologicalProcess regulation of peptidyl-serine phosphorylation of STAT protein Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json regulation of serine phosphorylation of STAT3 protein http://purl.obolibrary.org/obo/GO_0033139 GO:0008199 biolink:MolecularActivity ferric iron binding Binding to a ferric iron ion, Fe(III). go-plus.json http://purl.obolibrary.org/obo/GO_0008199 GO:0008198 biolink:MolecularActivity ferrous iron binding Binding to a ferrous iron ion, Fe(II). go-plus.json http://purl.obolibrary.org/obo/GO_0008198 GO:0008197 biolink:MolecularActivity obsolete yolk protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json yolk protein http://purl.obolibrary.org/obo/GO_0008197 GO:0033130 biolink:MolecularActivity acetylcholine receptor binding Binding to an acetylcholine receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0033130 OBA:1000090 biolink:OntologyClass membrane quality The quality of a membrane. go-plus.json membrane quality trait|quality of membrane http://purl.obolibrary.org/obo/OBA_1000090 GO:0033138 biolink:BiologicalProcess positive regulation of peptidyl-serine phosphorylation Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0033138 GO:0033137 biolink:BiologicalProcess negative regulation of peptidyl-serine phosphorylation Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0033137 GO:0033136 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033136 OBA:1000091 biolink:OntologyClass membrane morphology The morphology of a membrane. go-plus.json morphology of membrane|membrane morphology trait http://purl.obolibrary.org/obo/OBA_1000091 GO:0033135 biolink:BiologicalProcess regulation of peptidyl-serine phosphorylation Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine. go-plus.json http://purl.obolibrary.org/obo/GO_0033135 GO:0033134 biolink:MolecularActivity ubiquitin activating enzyme binding Binding to a ubiquitin activating enzyme, any of the E1 proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0033134 GO:0033133 biolink:BiologicalProcess positive regulation of glucokinase activity Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. go-plus.json glucokinase activator|stimulation of glucokinase activity|up-regulation of glucokinase activity|up regulation of glucokinase activity|upregulation of glucokinase activity http://purl.obolibrary.org/obo/GO_0033133 GO:0033132 biolink:BiologicalProcess negative regulation of glucokinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. go-plus.json glucokinase inhibitor|down-regulation of glucokinase activity|downregulation of glucokinase activity|down regulation of glucokinase activity|inhibition of glucokinase activity http://purl.obolibrary.org/obo/GO_0033132 GO:0033131 biolink:BiologicalProcess regulation of glucokinase activity Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. go-plus.json glucokinase regulator http://purl.obolibrary.org/obo/GO_0033131 GO:0047771 biolink:MolecularActivity carboxymethylhydantoinase activity Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+). EC:3.5.2.4|KEGG_REACTION:R02284|MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN|RHEA:12028 go-plus.json hydantoin hydrolase activity|L-5-carboxymethylhydantoin amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047771 CHEBI:24401 biolink:ChemicalSubstance glycosinolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24401 GO:0047770 biolink:MolecularActivity carboxylate reductase activity Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor. MetaCyc:CARBOXYLATE-REDUCTASE-RXN|EC:1.2.99.6 go-plus.json carboxylic acid reductase activity|aldehyde:(acceptor) oxidoreductase activity|aldehyde:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047770 CHEBI:24400 biolink:ChemicalSubstance glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_24400 CHEBI:24405 biolink:ChemicalSubstance glycosylglucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24405 CHEBI:24403 biolink:ChemicalSubstance glycosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_24403 CHEBI:24402 biolink:ChemicalSubstance glycosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24402 GO:0047779 biolink:MolecularActivity citrate-CoA ligase activity Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate. KEGG_REACTION:R01322|RHEA:21472|MetaCyc:CITRATE--COA-LIGASE-RXN|EC:6.2.1.18 go-plus.json citrate:CoA ligase (ADP-forming)|citrate:CoA ligase activity|citryl-CoA synthetase activity|citrate thiokinase activity http://purl.obolibrary.org/obo/GO_0047779 GO:0047778 biolink:MolecularActivity [citrate-(pro-3S)-lyase] thiolesterase activity Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate. MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN|EC:3.1.2.16|RHEA:13657 go-plus.json citrate-(pro-3S)-lyase thioesterase activity|citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity|citrate lyase deacetylase activity|citrate-(pro-3S)-lyase thiolesterase activity|[citrate-(pro-3S)-lyase] thioesterase activity|citrate (pro-3S)-lyase thiolesterase activity http://purl.obolibrary.org/obo/GO_0047778 GO:0047777 biolink:MolecularActivity (S)-citramalyl-CoA lyase activity Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate. MetaCyc:CITRAMALYL-COA-LYASE-RXN|EC:4.1.3.25|KEGG_REACTION:R00237|RHEA:22612 go-plus.json (+)-CMA-CoA lyase activity|(3S)-citramalyl-CoA pyruvate-lyase activity|citramalyl-CoA lyase activity|citramalyl coenzyme A lyase activity|(3S)-citramalyl-CoA lyase activity|(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming) http://purl.obolibrary.org/obo/GO_0047777 GO:0047776 biolink:MolecularActivity citramalate lyase activity Catalysis of the reaction: S-citramalate = acetate + pyruvate. RHEA:15545|MetaCyc:CITRAMALATE-LYASE-RXN|KEGG_REACTION:R00325|EC:4.1.3.22 go-plus.json citramalic-condensing enzyme|citramalic synthase activity|citramalate pyruvate-lyase activity|(S)-citramalate lyase activity|citramalate synthetase activity|(+)-citramalate pyruvate-lyase activity|(3S)-citramalate pyruvate-lyase activity|citramalate pyruvate lyase activity|(3S)-citramalate pyruvate-lyase (acetate-forming) http://purl.obolibrary.org/obo/GO_0047776 GO:0047775 biolink:MolecularActivity citramalate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA. EC:2.8.3.11|RHEA:17621|MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN go-plus.json acetyl-CoA:citramalate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0047775 GO:0047774 biolink:MolecularActivity cis-2-enoyl-CoA reductase (NADPH) activity Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH. MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN|EC:1.3.1.37 go-plus.json acyl-CoA:NADP+ cis-2-oxidoreductase activity|reductase, cis-2-enoyl coenzyme A|NADPH-dependent cis-enoyl-CoA reductase activity|cis-2-enoyl-coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_0047774 GO:0047773 biolink:MolecularActivity carnitinamidase activity Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+). MetaCyc:CARNITINAMIDASE-RXN|RHEA:17537|EC:3.5.1.73|KEGG_REACTION:R01922 go-plus.json carnitine amidase activity|L-carnitinamide amidohydrolase activity|L-carnitinamidase activity|L-carnitine amidase activity http://purl.obolibrary.org/obo/GO_0047773 GO:0047772 biolink:MolecularActivity carboxymethyloxysuccinate lyase activity Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate. MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN|EC:4.2.99.12|KEGG_REACTION:R01336|RHEA:12336 go-plus.json carboxymethyloxysuccinate glycolate-lyase activity|carboxymethyloxysuccinate glycolate-lyase (fumarate-forming) http://purl.obolibrary.org/obo/GO_0047772 UBERON:0001271 biolink:AnatomicalEntity pelvic girdle region The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. go-plus.json pelvic girdle|girdle - pelvic http://purl.obolibrary.org/obo/UBERON_0001271 UBERON:0001272 biolink:AnatomicalEntity innominate bone A fused bone consisting of the ilium, ischium and and pubis. Together with the sacrum and coccyx, it comprises the pelvis. [WP,modified]. go-plus.json coxal bone|pelvic bone|basipterygium|innominate bone|bone of pelvic girdle|innominate|os innominatum|hip bone|os coxae|os coxa http://purl.obolibrary.org/obo/UBERON_0001272 GO:0072739 biolink:BiologicalProcess response to anisomycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072739 GO:0072738 biolink:BiologicalProcess cellular response to diamide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus. go-plus.json cellular response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide http://purl.obolibrary.org/obo/GO_0072738 GO:0072737 biolink:BiologicalProcess response to diamide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus. go-plus.json response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide http://purl.obolibrary.org/obo/GO_0072737 GO:0072736 biolink:BiologicalProcess cellular response to tert-butyl hydroperoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus. go-plus.json cellular response to t-BOOH|cellular response to 2-methyl-prop-2-yl-hydroperoxide http://purl.obolibrary.org/obo/GO_0072736 GO:0072735 biolink:BiologicalProcess response to tert-butyl hydroperoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus. go-plus.json response to 2-methyl-prop-2-yl-hydroperoxide|response to t-BOOH http://purl.obolibrary.org/obo/GO_0072735 UBERON:0001279 biolink:AnatomicalEntity portal triad A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel go-plus.json trias hepatica|trias hepatica http://purl.obolibrary.org/obo/UBERON_0001279 CHEBI:24409 biolink:ChemicalSubstance glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24409 UBERON:0001278 biolink:AnatomicalEntity epithelium of large intestine An epithelium that is part of a large intestine [Automatically generated definition]. go-plus.json epithelial tissue of large intestine|large intestine epithelial tissue|large intestine epithelium|large intestinal epithelium http://purl.obolibrary.org/obo/UBERON_0001278 GO:0072734 biolink:BiologicalProcess cellular response to staurosporine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072734 GO:0072733 biolink:BiologicalProcess response to staurosporine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072733 CHEBI:73373 biolink:ChemicalSubstance cobalt(II)-factor III go-plus.json http://purl.obolibrary.org/obo/CHEBI_73373 CHEBI:24407 biolink:ChemicalSubstance glycosyl glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_24407 GO:0072732 biolink:BiologicalProcess cellular response to calcium ion starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions. go-plus.json cellular response to calcium starvation http://purl.obolibrary.org/obo/GO_0072732 CHEBI:24406 biolink:ChemicalSubstance glycosylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24406 GO:0072731 biolink:BiologicalProcess cellular response to papulacandin B Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072731 GO:0072730 biolink:BiologicalProcess response to papulacandin B Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072730 UBERON:0001277 biolink:AnatomicalEntity intestinal epithelium Epithelial layer that lines the intestine. go-plus.json epithelium of bowel|epithelial tissue of bowel|bowel epithelial tissue|intestine epithelium|epithelium of intestine|bowel epithelium|epithelial tissue of intestine|intestine epithelial tissue|villous epithelium http://purl.obolibrary.org/obo/UBERON_0001277 UBERON:0001276 biolink:AnatomicalEntity epithelium of stomach The epithelial layer of the stomach . go-plus.json gastric epithelium|stomach epithelial tissue|stomach epithelium|ventriculus epithelium|epithelium of ventriculus|epithelial tissue of ventriculus|ventriculus epithelial tissue|epithelial tissue of stomach http://purl.obolibrary.org/obo/UBERON_0001276 GO:0047782 biolink:MolecularActivity coniferin beta-glucosidase activity Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol. MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN|RHEA:12252|EC:3.2.1.126 go-plus.json coniferin beta-D-glucosidase activity|coniferin b-glucosidase activity|coniferin-hydrolyzing beta-glucosidase activity http://purl.obolibrary.org/obo/GO_0047782 GO:0047781 biolink:MolecularActivity citrullinase activity Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine. RHEA:11940|EC:3.5.1.20|MetaCyc:CITRULLINASE-RXN go-plus.json L-citrulline N5-carbamoyldihydrolase activity|citrulline ureidase activity|citrulline hydrolase activity|L-citrulline 5-N-carbamoyldihydrolase activity http://purl.obolibrary.org/obo/GO_0047781 CHEBI:73389 biolink:ChemicalSubstance O-ureido-L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73389 chebi_ph7_3 GO:0047780 biolink:MolecularActivity citrate dehydratase activity Catalysis of the reaction: citrate = cis-aconitate + H2O. RHEA:10228|KEGG_REACTION:R01325|MetaCyc:ACONITATEDEHYDR-RXN|MetaCyc:CITRATE-DEHYDRATASE-RXN|EC:4.2.1.3 go-plus.json aconitate hydratase activity|citrate hydro-lyase (cis-aconitate-forming) activity|citrate hydro-lyase activity|citrate hydro-lyase (cis-aconitate-forming) http://purl.obolibrary.org/obo/GO_0047780 CHEBI:24410 biolink:ChemicalSubstance glycosylphosphatidylinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24410 GO:0047789 biolink:MolecularActivity creatininase activity Catalysis of the reaction: creatinine + H(2)O = creatine. MetaCyc:CREATININASE-RXN|KEGG_REACTION:R01884|EC:3.5.2.10|RHEA:14533 go-plus.json creatinine amidohydrolase activity|creatinine hydrolase http://purl.obolibrary.org/obo/GO_0047789 GO:0047788 biolink:MolecularActivity 2-coumarate reductase activity Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH. MetaCyc:COUMARATE-REDUCTASE-RXN|KEGG_REACTION:R03709|EC:1.3.1.11|RHEA:21444 go-plus.json coumarate reductase activity|3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity|melilotate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047788 GO:0047787 biolink:MolecularActivity delta4-3-oxosteroid 5beta-reductase activity Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+. MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN|MetaCyc:CORTISONE-BETA-REDUCTASE-RXN|EC:1.3.1.3 go-plus.json cortisone beta-reductase activity|cortisone delta(4)-5-beta-reductase activity|cholestenone 5beta-reductase activity|androstenedione 5beta-reductase activity|testosterone 5beta-reductase activity|delta4-3-ketosteroid 5beta-reductase activity|steroid 5beta-reductase activity|delta4-3-oxosteroid 5-beta-reductase activity|delta(4)-3-ketosteroid 5-beta-reductase activity|5beta-reductase activity|cortisone delta4-5beta-reductase activity|4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity|cholestenone 5-beta-reductase activity|cortisone b-reductase activity|steroid 5-beta-reductase activity|testosterone 5-beta-reductase activity|5-beta-reductase activity|androstenedione 5-beta-reductase activity|cholestenone 5b-reductase activity|delta(4)-5-beta-reductase activity|3-oxo-delta4-steroid 5beta-reductase activity|delta4-hydrogenase activity|cortisone 5beta-reductase activity|3-oxo-Delta(4)-steroid 5-beta-reductase activity|delta4-5beta-reductase activity|3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity|5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity|cortisone 5-beta-reductase activity|delta(4)-hydrogenase activity http://purl.obolibrary.org/obo/GO_0047787 GO:0047786 biolink:MolecularActivity cortisone alpha-reductase activity Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH. MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN|KEGG_REACTION:R02892|RHEA:17981 go-plus.json cortisone delta4-5alpha-reductase activity|microsomal steroid reductase (5alpha)|NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity|cortisone a-reductase activity|delta4-3-ketosteroid reductase (5alpha)|4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity|delta4-3-oxosteroid-5alpha-reductase|delta4-5alpha-reductase activity http://purl.obolibrary.org/obo/GO_0047786 GO:0047785 biolink:MolecularActivity cortisol sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+). KEGG_REACTION:R02839|MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN|EC:2.8.2.18|RHEA:11884 go-plus.json 3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity|glucocorticosteroid sulfotransferase activity|cortisol sulphotransferase activity|glucocorticoid sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047785 GO:0047784 biolink:MolecularActivity cortisol O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate. EC:2.3.1.27|KEGG_REACTION:R02837|RHEA:17073|MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN go-plus.json corticosteroid-21-O-acetyltransferase activity|corticosteroid acetyltransferase activity|cortisol acetyltransferase activity|acetyl-CoA:cortisol O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047784 GO:0047783 biolink:MolecularActivity corticosterone 18-monooxygenase activity Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O. MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN|RHEA:11872|EC:1.14.15.5 go-plus.json corticosterone 18-hydroxylase activity|corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)|corticosterone methyl oxidase activity http://purl.obolibrary.org/obo/GO_0047783 UBERON:0001260 biolink:AnatomicalEntity serosa of urinary bladder A serous membrane that is part of a urinary bladder [Automatically generated definition]. go-plus.json serosa of bladder|serous membrane of urinary bladder|bladder serosa|serous membrane of bladder|urinary bladder serosa|urinary bladder serous membrane|serous coat of urinary bladder|tunica serosa (vesica urinaria)|bladder serous membrane|serous coat of bladder|visceral peritoneum of urinary bladder|tunica serosa vesicae http://purl.obolibrary.org/obo/UBERON_0001260 UBERON:0001262 biolink:AnatomicalEntity wall of intestine An anatomical wall that is part of a intestine [Automatically generated definition]. go-plus.json anatomical wall of bowel|intestine wall|wall of bowel|anatomical wall of intestine|bowel wall|bowel anatomical wall|bowel wall|intestine anatomical wall|intestinal wall http://purl.obolibrary.org/obo/UBERON_0001262 UBERON:0001261 biolink:AnatomicalEntity lamina propria of urinary bladder A lamina propria that is part of a urinary bladder [Automatically generated definition]. go-plus.json urinary bladder lamina propria|urinary bladder lamina propria mucosa|bladder lamina propria mucosa|lamina propria mucosae of urinary bladder|lamina propria of bladder|lamina propria mucosae of bladder|lamina propria mucosa of urinary bladder|bladder lamina propria mucosae|bladder lamina propria|lamina propria mucosa of bladder|urinary bladder lamina propria mucosae http://purl.obolibrary.org/obo/UBERON_0001261 GO:0072729 biolink:BiologicalProcess cellular response to Gentian violet Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus. go-plus.json cellular response to crystal violet|cellular response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride http://purl.obolibrary.org/obo/GO_0072729 GO:0072728 biolink:BiologicalProcess response to Gentian violet Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus. go-plus.json response to crystal violet|response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride http://purl.obolibrary.org/obo/GO_0072728 GO:0072727 biolink:BiologicalProcess cellular response to CCCP Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus. go-plus.json cellular response to carbonyl cyanide m-chlorophenyl hydrazone http://purl.obolibrary.org/obo/GO_0072727 GO:0072726 biolink:BiologicalProcess response to CCCP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus. go-plus.json response to carbonyl cyanide m-chlorophenyl hydrazone http://purl.obolibrary.org/obo/GO_0072726 GO:0072725 biolink:BiologicalProcess cellular response to 4-nitroquinoline N-oxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072725 UBERON:0001268 biolink:AnatomicalEntity peritoneal fluid Transudate contained in the peritoneal cavity. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001268 GO:0072724 biolink:BiologicalProcess response to 4-nitroquinoline N-oxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072724 GO:0072723 biolink:BiologicalProcess cellular response to amitrole Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus. go-plus.json cellular response to 3-amino-1,2,4-triazole http://purl.obolibrary.org/obo/GO_0072723 GO:0072722 biolink:BiologicalProcess response to amitrole Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus. go-plus.json response to 3-amino-1,2,4-triazole http://purl.obolibrary.org/obo/GO_0072722 GO:0072721 biolink:BiologicalProcess cellular response to dithiothreitol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus. go-plus.json cellular response to DTT|cellular response to 1,4-dithiothreitol http://purl.obolibrary.org/obo/GO_0072721 GO:0072720 biolink:BiologicalProcess response to dithiothreitol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus. go-plus.json response to 1,4-dithiothreitol|response to DTT http://purl.obolibrary.org/obo/GO_0072720 UBERON:0001264 biolink:AnatomicalEntity pancreas An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001264 UBERON:0001263 biolink:AnatomicalEntity pancreatic acinus The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct. go-plus.json acinus pancreaticus|pancreas acinus|pancreatic acinar|pancreatic acini http://purl.obolibrary.org/obo/UBERON_0001263 CHEBI:73388 biolink:ChemicalSubstance caldariellaquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73388 chebi_ph7_3 UBERON:0001265 biolink:AnatomicalEntity trabecula of spleen A trabecula that is part of a spleen. go-plus.json splenic trabecula|spleen trabeculum http://purl.obolibrary.org/obo/UBERON_0001265 CHEBI:73387 biolink:ChemicalSubstance caldariellaquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_73387 chebi_ph7_3 GO:0047793 biolink:MolecularActivity cycloeucalenol cycloisomerase activity Catalysis of the reaction: cycloeucalenol = obtusifoliol. RHEA:22800|MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN|EC:5.5.1.9|KEGG_REACTION:R03775 go-plus.json cycloeucalenol lyase (cyclopropane-decyclizing)|cycloeucalenol--obtusifoliol isomerase activity|cycloeucalenol-obtusifoliol isomerase activity http://purl.obolibrary.org/obo/GO_0047793 GO:0047792 biolink:MolecularActivity cyanohydrin beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside. RHEA:12853|EC:2.4.1.85 go-plus.json uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity|uridine diphosphoglucose-cyanohydrin glucosyltransferase activity|UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity|UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity|UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity|UGT85B1 activity|cyanohydrin b-glucosyltransferase activity|UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047792 GO:0047791 biolink:MolecularActivity cucurbitacin delta23-reductase activity Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+. EC:1.3.1.5|MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN go-plus.json 23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity|NAD(P)H: cucurbitacin B delta23-oxidoreductase activity|cucurbitacin delta(23) reductase activity|cucurbitacin D23-reductase activity http://purl.obolibrary.org/obo/GO_0047791 GO:0047790 biolink:MolecularActivity creatinine deaminase activity Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3. MetaCyc:CREATININE-DEAMINASE-RXN|EC:3.5.4.21|RHEA:12681 go-plus.json creatinine hydrolase|creatinine iminohydrolase activity|creatinine desiminase activity http://purl.obolibrary.org/obo/GO_0047790 UBERON:0001249 biolink:AnatomicalEntity spleen lymphoid follicle The area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur go-plus.json spleen lymphoid follicle|splenic lymphatic follicle|lymphoid nodule of spleen|lymphatic follicle of spleen|Malpighian body|splenic lymphoid follicle|spleen B cell follicle|spleen lymphoid nodule|lymphoid follicle of spleen|splenic B cell follicle http://purl.obolibrary.org/obo/UBERON_0001249 GO:0047799 biolink:MolecularActivity cyclopentanone monooxygenase activity Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+). EC:1.14.13.16|MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN|RHEA:15737|KEGG_REACTION:R02554 go-plus.json cyclopentanone oxygenase activity|cyclopentanone 1,2-monooxygenase activity|cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing) http://purl.obolibrary.org/obo/GO_0047799 GO:0047798 biolink:MolecularActivity cyclomaltodextrinase activity Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin. MetaCyc:CYCLOMALTODEXTRINASE-RXN|RHEA:23980|EC:3.2.1.54 go-plus.json cycloheptaglucanase activity|cyclodextrinase activity|cyclomaltodextrin dextrin-hydrolase (decyclizing)|cyclohexaglucanase activity http://purl.obolibrary.org/obo/GO_0047798 GO:0047797 biolink:MolecularActivity cyclohexanone dehydrogenase activity Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone. RHEA:21780|EC:1.3.99.14|MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN|KEGG_REACTION:R02234 go-plus.json cyclohexanone:acceptor 2-oxidoreductase activity|cyclohexanone:(acceptor) 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047797 GO:0047796 biolink:MolecularActivity cyclohexane-1,3-dione hydrolase activity Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+). RHEA:16473|MetaCyc:CYCLOHEXANE-13-DIONE-HYDROLASE-RXN|EC:3.7.1.10|KEGG_REACTION:R03211 go-plus.json 1,3-cyclohexanedione hydrolase activity|cyclohexane-1,3-dione acylhydrolase (decyclizing) http://purl.obolibrary.org/obo/GO_0047796 GO:0047795 biolink:MolecularActivity cyclohexane-1,2-diol dehydrogenase activity Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH. RHEA:18141|MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN|EC:1.1.1.174 go-plus.json trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047795 GO:0047794 biolink:MolecularActivity cyclohexadienyl dehydrogenase activity Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2. MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN|EC:1.3.1.43|RHEA:12256 go-plus.json L-arogenate:NAD(+) oxidoreductase activity|pretyrosine dehydrogenase activity|L-arogenate:NAD+ oxidoreductase (decarboxylating)|arogenate dehydrogenase activity|L-arogenate:NAD+ oxidoreductase activity|arogenic dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047794 GO:0072759 biolink:BiologicalProcess cellular response to topoisomerase inhibitor Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072759 GO:0072758 biolink:BiologicalProcess response to topoisomerase inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072758 UBERON:0025261 biolink:AnatomicalEntity thalamic fiber tract go-plus.json thalamic fiber tracts http://purl.obolibrary.org/obo/UBERON_0025261 GO:0072757 biolink:BiologicalProcess cellular response to camptothecin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus. go-plus.json cellular response to CPT http://purl.obolibrary.org/obo/GO_0072757 UBERON:0001256 biolink:AnatomicalEntity wall of urinary bladder An anatomical wall that lines the insider of a urinary bladder. go-plus.json anatomical wall of bladder|urinary bladder anatomical wall|wall of bladder|bladder anatomical wall|bladder wall|urinary bladder wall|anatomical wall of urinary bladder http://purl.obolibrary.org/obo/UBERON_0001256 GO:0072756 biolink:BiologicalProcess cellular response to paraquat Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072756 GO:0072755 biolink:BiologicalProcess cellular response to benomyl Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072755 UBERON:0001259 biolink:AnatomicalEntity mucosa of urinary bladder the mucous membrane lining the urinary bladder go-plus.json tunica mucosa (vesica urinaria)|bladder organ mucosa|urinary bladder mucous membrane|tunica mucosa vesicae|bladder mucous membrane|tunica mucosa vesicae urinariae|mucous membrane of urinary bladder|bladder mucosa|mucous membrane of bladder|mucosa of bladder|urinary bladder mucosa http://purl.obolibrary.org/obo/UBERON_0001259 UBERON:0001258 biolink:AnatomicalEntity neck of urinary bladder The constricted portion of the urinary bladder, formed by the meeting of its inferolateral surfaces proximal to the opening of the urethra[MP]. go-plus.json vesical neck|urinary bladder neck|cervix vesicae urinariae|collum vesicae|neck of bladder|bladder neck|cervix vesicae http://purl.obolibrary.org/obo/UBERON_0001258 GO:0072754 biolink:BiologicalProcess cellular response to purvalanol A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072754 CHEBI:324935 biolink:ChemicalSubstance fumagillol go-plus.json http://purl.obolibrary.org/obo/CHEBI_324935 chebi_ph7_3 UBERON:0001253 biolink:AnatomicalEntity lamina propria of ureter A lamina propria that is part of a ureter [Automatically generated definition]. go-plus.json ureter lamina propria|lamina propria mucosae of ureter|ureter lamina propria mucosa|lamina propria mucosa of ureter|ureter lamina propria mucosae http://purl.obolibrary.org/obo/UBERON_0001253 GO:0072753 biolink:BiologicalProcess cellular response to glutathione Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072753 UBERON:0001252 biolink:AnatomicalEntity adventitia of ureter An adventitia that is part of a ureter. go-plus.json external adventitia of ureter|tunica adventitia (ureter)|tunica adventitia ureteris|ureter adventitia|ureteral adventitia http://purl.obolibrary.org/obo/UBERON_0001252 GO:0072752 biolink:BiologicalProcess cellular response to rapamycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072752 GO:0072751 biolink:BiologicalProcess cellular response to L-thialysine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus. go-plus.json cellular response to thialysine http://purl.obolibrary.org/obo/GO_0072751 UBERON:0001255 biolink:AnatomicalEntity urinary bladder distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. go-plus.json vesica urinaria|urocyst|vesica|bladder http://purl.obolibrary.org/obo/UBERON_0001255 UBERON:0001254 biolink:AnatomicalEntity urothelium of ureter The luminal epithelium of the tube that conducts the urine from the renal pelvis to the bladder[MP] go-plus.json transitional epithelium of ureter|ureter luminal urothelium|ureter transitional epithelium|ureter urothelium http://purl.obolibrary.org/obo/UBERON_0001254 GO:0072750 biolink:BiologicalProcess cellular response to leptomycin B Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072750 CHEBI:73398 biolink:ChemicalSubstance indole skeleton go-plus.json http://purl.obolibrary.org/obo/CHEBI_73398 chebi_ph7_3 UBERON:0001238 biolink:AnatomicalEntity lamina propria of small intestine Lamina propria that is part_of the small intestine. go-plus.json lamina propria mucosae of small intestine|lamina propria mucosa of small bowel|small bowel lamina propria mucosae|small bowel lamina propria|lamina propria of mucosa of small intestine|lamina propria mucosa of small intestine|small bowel lamina propria mucosa|small intestine lamina propria mucosa|lamina propria of small bowel|lamina propria mucosae of small bowel|small intestine lamina propria mucosae|small intestine lamina propria http://purl.obolibrary.org/obo/UBERON_0001238 GO:0072749 biolink:BiologicalProcess cellular response to cytochalasin B Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072749 GO:0072748 biolink:BiologicalProcess cellular response to tacrolimus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus. go-plus.json cellular response to FK506|cellular response to tacrolimus hydrate http://purl.obolibrary.org/obo/GO_0072748 GO:0072747 biolink:BiologicalProcess cellular response to chloramphenicol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072747 GO:0072746 biolink:BiologicalProcess cellular response to tetracycline Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072746 UBERON:0001246 biolink:AnatomicalEntity interlobular bile duct The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad. go-plus.json interlobular ductule http://purl.obolibrary.org/obo/UBERON_0001246 GO:0072745 biolink:BiologicalProcess cellular response to antimycin A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072745 UBERON:0001245 biolink:AnatomicalEntity anus Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts. go-plus.json proctodeum|anal orifice|anal opening|opening of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0001245 GO:0072744 biolink:BiologicalProcess cellular response to trichodermin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072744 GO:0072743 biolink:BiologicalProcess cellular response to erythromycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072743 UBERON:0001247 biolink:AnatomicalEntity falciform ligament A ligament that attaches the liver to the anterior body wall. It is a broad and thin antero-posterior peritoneal fold, falciform in shape, its base being directed downward and backward and its apex upward and backward. It is a remnant of the ventral mesentery of the fetus. It is situated in an antero-posterior plane but lies obliquely, so that one surface faces forward and is in contact with the peritoneum behind the right rectus and the diaphragm, while the other is directed backward and is in contact with the left lobe of the liver. It is attached by its left margin to the under surface of the diaphragm and the posterior surface of the sheath of the right Rectus as low down as the umbilicus; by its right margin it extends from the notch on the anterior margin of the liver, as far back as the posterior surface. It is composed of two layers of peritoneum closely united together. Its base or free edge contains between its layers the round ligament and the paraumbilical veins[WP]. go-plus.json falciform ligament of liver|ligamentum falciforme (hepatis)|ligamentum falciforme hepatis http://purl.obolibrary.org/obo/UBERON_0001247 UBERON:0001242 biolink:AnatomicalEntity intestinal mucosa Mucosal layer that lines the intestine. go-plus.json mucosa of bowel|mucosa of organ of bowel|bowel organ mucosa|mucous membrane of intestine|mucosa of intestine|mucosa of organ of intestine|intestine mucosa|bowel mucosa of organ|organ mucosa of bowel|tunica mucosa intestini|bowel mucous membrane|bowel mucosa|intestine mucosa of organ|organ mucosa of intestine|intestine mucous membrane|intestine organ mucosa|mucous membrane of bowel http://purl.obolibrary.org/obo/UBERON_0001242 GO:0072742 biolink:BiologicalProcess SAGA complex localization to transcription regulatory region Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene. go-plus.json SAGA complex localization to promoter|SAGA complex recruitment http://purl.obolibrary.org/obo/GO_0072742 GO:0072741 biolink:BiologicalProcess protein localization to cell division site A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division. go-plus.json protein localisation to cell division site http://purl.obolibrary.org/obo/GO_0072741 GO:0072740 biolink:BiologicalProcess cellular response to anisomycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072740 UBERON:0001243 biolink:AnatomicalEntity serosa of intestine A serous membrane that is part of a wall of intestine [Automatically generated definition]. go-plus.json visceral peritoneum of intestine|bowel anatomical wall serosa|anatomical wall of intestine serosa|wall of bowel serous membrane|bowel wall serosa|serous membrane of intestine anatomical wall|anatomical wall of intestine serous membrane|wall of bowel serosa|serosa of bowel wall|bowel wall serous membrane|serosa of anatomical wall of intestine|bowel anatomical wall serous membrane|serosa of intestinal wall|intestine wall serosa|anatomical wall of bowel serosa|wall of intestine serous membrane|intestinal wall serosa|serosa of wall of bowel|intestinal serosa|intestine anatomical wall serous membrane|intestine serosa|serous membrane of intestinal wall|serosa of bowel anatomical wall|serous membrane of anatomical wall of bowel|serosa of wall of intestine|serous membrane of intestine wall|serous membrane of wall of bowel|intestine anatomical wall serosa|serosa of intestine anatomical wall|intestinal wall serous membrane|serous membrane of bowel anatomical wall|serous membrane of anatomical wall of intestine|serous membrane of bowel wall|intestine wall serous membrane|serous membrane of wall of intestine|serosa of anatomical wall of bowel|anatomical wall of bowel serous membrane|serosa of intestine wall|wall of intestine serosa http://purl.obolibrary.org/obo/UBERON_0001243 OBO:uberon/core#channels_into biolink:OntologyClass channels_into channels_into go-plus.json http://purl.obolibrary.org/obo/uberon/core#channels_into OBA:1000028 biolink:OntologyClass membrane permeability The permeability of a membrane. go-plus.json permeability of membrane|membrane permeability trait http://purl.obolibrary.org/obo/OBA_1000028 CHEBI:310312 biolink:ChemicalSubstance isoliquiritigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_310312 SO:0000235 biolink:SequenceFeature TF_binding_site A DNA site where a transcription factor binds. go-plus.json TF binding site|transcription factor binding site http://purl.obolibrary.org/obo/SO_0000235 SOFA SO:0000234 biolink:SequenceFeature mRNA Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. http://en.wikipedia.org/wiki/MRNA|http://www.gencodegenes.org/gencode_biotypes.html go-plus.json messenger RNA|protein_coding_transcript|INSDC_feature:mRNA http://purl.obolibrary.org/obo/SO_0000234 SOFA NCBITaxon:214684 biolink:OrganismalEntity Cryptococcus neoformans var. neoformans JEC21 go-plus.json Cryptococcus neoformans JEC21|Filobasidiella neoformans var. neoformans strain JEC21|Cryptococcus neoformans var. neoformans strain JEC21|Cryptococcus neoformans var. neoformans serotype D JEC21 http://purl.obolibrary.org/obo/NCBITaxon_214684 GO:0072760 biolink:BiologicalProcess cellular response to GW 7647 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072760 OBA:1000035 biolink:OntologyClass lens of camera-type eye opacity The opacity of a lens of camera-type eye. go-plus.json lens of camera-type eye opacity trait|lens opacity|opacity of lens of camera-type eye|lens transparency http://purl.obolibrary.org/obo/OBA_1000035 SO:0000233 biolink:SequenceFeature mature_transcript A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified. http://en.wikipedia.org/wiki/Mature_transcript go-plus.json mature transcript http://purl.obolibrary.org/obo/SO_0000233 SOFA NCBITaxon:214687 biolink:OrganismalEntity Musa acuminata subsp. malaccensis go-plus.json Musa acuminata var. malaccensis|wild Malaysian banana|true apple banana|pisang utan http://purl.obolibrary.org/obo/NCBITaxon_214687 GO:0072766 biolink:BiologicalProcess centromere clustering at the mitotic interphase nuclear envelope The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei. go-plus.json centromere clustering at the mitotic nuclear envelope|centromere-SPB clustering|rabl configuration|kinetochore localization at spindle pole body|kinetochore clustering at spindle pole body|centromere clustering at the nuclear periphery|kinetochore clustering at SPB|kinetochore clustering at the old mitotic spindle pole body http://purl.obolibrary.org/obo/GO_0072766 GO:0072765 biolink:BiologicalProcess centromere localization A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location. go-plus.json establishment and maintenance of kinetochore localization|kinetochore localisation|kinetochore localization http://purl.obolibrary.org/obo/GO_0072765 UBERON:4200230 biolink:AnatomicalEntity surface of bone An anatomical surface that is part of a bone. go-plus.json bone surface http://purl.obolibrary.org/obo/UBERON_4200230 GO:0072764 biolink:BiologicalProcess cellular response to reversine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072764 GO:0072763 biolink:BiologicalProcess cellular response to hesperadin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072763 GO:0072762 biolink:BiologicalProcess cellular response to carbendazim Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072762 GO:0072761 biolink:BiologicalProcess cellular response to capsazepine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072761 UBERON:0001293 biolink:AnatomicalEntity outer medulla of kidney The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla[GO]. go-plus.json kidney outer medulla|set of outer region of renal pyramids|zona externa (medullaris renalis)|outer zone of renal medulla|outer zone of medulla of kidney|renal outer medulla|outer renal medulla|zona externa medullae renalis http://purl.obolibrary.org/obo/UBERON_0001293 UBERON:0001292 biolink:AnatomicalEntity distal convoluted tubule The first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. go-plus.json distal convoluted renal tubule|tubulus contortus distalis|tubulus contortus distalis|tubulus convolutus distalis|second convoluted tubule http://purl.obolibrary.org/obo/UBERON_0001292 UBERON:2001269 biolink:AnatomicalEntity regenerating fin/limb Fin or limb undergoing the process of regeneration. go-plus.json regenerating fins http://purl.obolibrary.org/obo/UBERON_2001269 UBERON:0001295 biolink:AnatomicalEntity endometrium the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy go-plus.json uterine endometrium|uterine mucosa|tunica mucosa uteri|tunica mucosa (endometrium)|uterine mucous membrane http://purl.obolibrary.org/obo/UBERON_0001295 UBERON:0001294 biolink:AnatomicalEntity inner medulla of kidney Innermost region of the mammalian kidney. go-plus.json zona interna medullae renalis|kidney inner medulla|inner zone of renal medulla|inner zone of medulla of kidney|zona interna (medullaris renalis)|renal inner medulla|inner renal medulla|set of inner region of renal pyramids http://purl.obolibrary.org/obo/UBERON_0001294 UBERON:0001291 biolink:AnatomicalEntity thick ascending limb of loop of Henle the distal sub-portion of the ascending loop of Henle which is lined by simple cuboidal epithelium and enters the renal cortex to empty a hypotonic filtrate into the distal convoluted tubule go-plus.json tubulus rectus distalis|distal straight tubule|ascending thick limb|thick ascending limb|straight portion of distal convoluted tubule|thick ascending limb of distal tubule|thick ascending limb of Henle's loop|straight portion of distal convoluted renal tubule|tubulus rectus distalis|loop of Henle ascending limb thick segment http://purl.obolibrary.org/obo/UBERON_0001291 UBERON:0001290 biolink:AnatomicalEntity proximal straight tubule The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. go-plus.json pars recta|S3|segment 3 of proximal tubule|tubulus rectus proximalis|proximal tubule segment 3|thick descending limb of proximal tubule|pars recta tubuli renalis http://purl.obolibrary.org/obo/UBERON_0001290 UBERON:0001297 biolink:AnatomicalEntity serosa of uterus Outer serosa layer of the uterus. go-plus.json visceral peritoneum of uterus|uterine serosa|serous coat of uterus|tunica serosa uteri|perimetrium|serous membrane of uterus|tunica serosa (perimetrium)|uterus serosa|uterus serous membrane http://purl.obolibrary.org/obo/UBERON_0001297 UBERON:0001299 biolink:AnatomicalEntity glans penis the conic expansion of the corpus spongiosum that forms the head of the penis go-plus.json coronal sulcus|glans|balanus http://purl.obolibrary.org/obo/UBERON_0001299 SO:0000253 biolink:SequenceFeature tRNA Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. http://en.wikipedia.org/wiki/TRNA go-plus.json transfer RNA|INSDC_feature:tRNA|transfer ribonucleic acid|INSDC_qualifier:unknown http://purl.obolibrary.org/obo/SO_0000253 SOFA SO:0000252 biolink:SequenceFeature rRNA rRNA is an RNA component of a ribosome that can provide both structural scaffolding and catalytic activity. http://en.wikipedia.org/wiki/RRNA go-plus.json ribosomal ribonucleic acid|INSDC_feature:rRNA|INSDC_qualifier:unknown|ribosomal RNA http://purl.obolibrary.org/obo/SO_0000252 SOFA OBA:1000019 biolink:OntologyClass nucleus morphology The morphology of a nucleus. go-plus.json nucleus morphology trait|morphology of nucleus http://purl.obolibrary.org/obo/OBA_1000019 UBERON:0001282 biolink:AnatomicalEntity intralobular bile duct the tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule go-plus.json cholangiole|duct of Herring|canal of Hering|canals of Hering|intrahepatic bile ductule|ductus interlobularis bilifer|canal of Herring http://purl.obolibrary.org/obo/UBERON_0001282 UBERON:0001281 biolink:AnatomicalEntity hepatic sinusoid Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers. go-plus.json hepatic sinusoids|vas sinusoideum|liver sinusoid|vas capillare sinusoideum|sinusoid of liver|liver hepatic sinusoids|liver sinusoidal blood vessel|sinusoidal blood vessel of liver http://purl.obolibrary.org/obo/UBERON_0001281 UBERON:0001283 biolink:AnatomicalEntity bile canaliculus An intercellular channel that takes up bile from hepatocytes, transporting it to the bile ducts. go-plus.json bile canaliculi|bile capillary|biliary canaliculus http://purl.obolibrary.org/obo/UBERON_0001283 UBERON:0001280 biolink:AnatomicalEntity liver parenchyma The functional units of the liver including the lobules. go-plus.json hepatic parenchyme|liver parenchyme|parenchyma of liver|hepatic parenchyma http://purl.obolibrary.org/obo/UBERON_0001280 UBERON:0001289 biolink:AnatomicalEntity descending limb of loop of Henle the portion of the renal tubule that constitutes the proximal part of the loop of Henle, has low permeability to ions and urea, and is highly permeable to water; it consists of an initial short thick segment lined by low simple cuboidal epithelium and a long thin segment lined by simple squamous epithelium; however, this distinction is not as important physiologically as in the ascending limb, so often the two are treated as one structure go-plus.json loop of Henle descending limb|descending limb of Henle's loop|descending limb http://purl.obolibrary.org/obo/UBERON_0001289 UBERON:0001285 biolink:AnatomicalEntity nephron The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP] go-plus.json nephroneum|mature nephron|tubulus renalis http://purl.obolibrary.org/obo/UBERON_0001285 UBERON:0001288 biolink:AnatomicalEntity loop of Henle the section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine go-plus.json Henle loop|Henle's loop|ansa nephroni http://purl.obolibrary.org/obo/UBERON_0001288 UBERON:0001287 biolink:AnatomicalEntity proximal convoluted tubule The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. go-plus.json PCT|kidney proximal convoluted tubule|proximal convoluted renal tubule|tubulus contortus proximalis|renal proximal convoluted tubule|tubulus contortus proximalis|1st convoluted tubule|first convoluted tubule|tubulus convolutus proximalis http://purl.obolibrary.org/obo/UBERON_0001287 GO:0008329 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008329 GO:0008328 biolink:CellularComponent ionotropic glutamate receptor complex A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. go-plus.json http://purl.obolibrary.org/obo/GO_0008328 GO:0008327 biolink:MolecularActivity methyl-CpG binding Binding to a methylated cytosine/guanine dinucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0008327 GO:0008326 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008326 GO:0008325 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008325 GO:0047933 biolink:MolecularActivity glucose-1,6-bisphosphate synthase activity Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+). MetaCyc:GLUCOSE-16-BISPHOSPHATE-SYNTHASE-RXN|Reactome:R-HSA-8955760|RHEA:16769|EC:2.7.1.106|KEGG_REACTION:R01660 go-plus.json 3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|glucose 1,6-diphosphate synthase activity|glucose-1,6-bisphosphate synthetase activity|3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047933 GO:0047932 biolink:MolecularActivity glucosamine N-acetyltransferase activity Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+). KEGG_REACTION:R01204|RHEA:21332|EC:2.3.1.3|MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN go-plus.json glucosamine acetyltransferase activity|acetyl-CoA:D-glucosamine N-acetyltransferase activity|glucosamine acetylase activity http://purl.obolibrary.org/obo/GO_0047932 GO:0008324 biolink:MolecularActivity cation transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other. go-plus.json transmembrane cation transporter activity http://purl.obolibrary.org/obo/GO_0008324 GO:0047931 biolink:MolecularActivity glucosamine kinase activity Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate. RHEA:10948|EC:2.7.1.8|MetaCyc:GLUCOSAMINE-KINASE-RXN go-plus.json ATP:D-glucosamine phosphotransferase activity|glucosamine kinase (phosphorylating)|aminodeoxyglucose kinase activity|ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047931 GO:0008323 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008323 GO:0047930 biolink:MolecularActivity glucosaminate ammonia-lyase activity Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3. EC:4.3.1.9|RHEA:12488|MetaCyc:4.3.1.21-RXN go-plus.json glucosaminic dehydrase activity|D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)|D-glucosaminate dehydratase activity|aminodeoxygluconate ammonia-lyase activity|2-amino-2-deoxy-D-gluconate ammonia-lyase activity|D-glucosaminic acid dehydrase activity|aminodeoxygluconate dehydratase activity|2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity|acetylenemonocarboxylic acid hydrase activity|D-glucosaminate ammonia-lyase activity http://purl.obolibrary.org/obo/GO_0047930 GO:0008322 biolink:MolecularActivity obsolete Pro-X carboxypeptidase activity OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid. go-plus.json Pro-X carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0008322 CHEBI:83579 biolink:ChemicalSubstance 3-(methylthio)propanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_83579 CHEBI:83578 biolink:ChemicalSubstance 2-carboxyhexacosanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83578 chebi_ph7_3 GO:0008321 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008321 GO:0008320 biolink:MolecularActivity protein transmembrane transporter activity Enables the transfer of a protein from one side of a membrane to the other. Reactome:R-HSA-5229111|Reactome:R-HSA-5250616|Reactome:R-HSA-5205661|Reactome:R-HSA-1268022|Reactome:R-HSA-5246514|Reactome:R-HSA-5244506|Reactome:R-HSA-5228406|Reactome:R-HSA-5244428|Reactome:R-HSA-5250972|Reactome:R-HSA-5250884|Reactome:R-HSA-184269|Reactome:R-HSA-5244404|Reactome:R-HSA-5336420|Reactome:R-HSA-5210947|Reactome:R-HSA-3149434|Reactome:R-HSA-9698933|Reactome:R-HSA-1299475|Reactome:R-HSA-9698930|Reactome:R-HSA-5210943|Reactome:R-HSA-9636375 go-plus.json protein channel activity http://purl.obolibrary.org/obo/GO_0008320 CHEBI:83577 biolink:ChemicalSubstance 2-carboxytetracosanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83577 chebi_ph7_3 CHEBI:83575 biolink:ChemicalSubstance monofluorobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_83575 CHEBI:83574 biolink:ChemicalSubstance (R)-3,5-bisphosphomevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83574 GO:0047939 biolink:MolecularActivity L-glucuronate reductase activity Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH. MetaCyc:GLUCURONATE-REDUCTASE-RXN|EC:1.1.1.19|RHEA:14909|KEGG_REACTION:R01481|Reactome:R-HSA-5661256 go-plus.json TPN-L-gulonate dehydrogenase activity|aldehyde reductase II activity|D-glucuronate dehydrogenase activity|D-glucuronate reductase activity|glucuronate reductase activity|glucuronate dehydrogenase activity|NADP-L-gulonate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047939 GO:0047938 biolink:MolecularActivity glucose-6-phosphate 1-epimerase activity Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate. EC:5.1.3.15|RHEA:16249|MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN go-plus.json glucose-6 phosphate 1-epimerase activity|D-glucose-6-phosphate 1-epimerase activity http://purl.obolibrary.org/obo/GO_0047938 GO:0047937 biolink:MolecularActivity glucose-1-phosphate phosphodismutase activity Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate. MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN|EC:2.7.1.41|RHEA:16397 go-plus.json phosphodismutase activity|D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|glucose 1-phosphate transphosphorylase activity http://purl.obolibrary.org/obo/GO_0047937 GO:0047936 biolink:MolecularActivity glucose 1-dehydrogenase [NAD(P)] activity Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. EC:1.1.1.47|MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN go-plus.json D-glucose dehydrogenase (NAD(P))|hexose phosphate dehydrogenase activity|beta-D-glucose:NAD(P)+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047936 GO:0047935 biolink:MolecularActivity glucose 1-dehydrogenase (NADP+) activity Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH. RHEA:14405|EC:1.1.1.119|MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN go-plus.json D-glucose:NADP+ 1-oxidoreductase activity|nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity|NADP-linked aldohexose dehydrogenase activity|NADP-dependent glucose dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047935 GO:0047934 biolink:MolecularActivity glucose 1-dehydrogenase (NAD+) activity Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH. EC:1.1.1.118|RHEA:14293|MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN go-plus.json D-glucose:NAD+ 1-oxidoreductase activity|D-aldohexose dehydrogenase activity|D-glucose:NAD oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047934 GO:0008339 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008339 GO:0008338 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008338 GO:0008337 biolink:MolecularActivity obsolete selectin OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins. go-plus.json selectin http://purl.obolibrary.org/obo/GO_0008337 GO:0008336 biolink:MolecularActivity gamma-butyrobetaine dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate. MetaCyc:1.14.11.1-RXN|EC:1.14.11.1|RHEA:24028|KEGG_REACTION:R02397|Reactome:R-HSA-71261 go-plus.json alpha-butyrobetaine hydroxylase activity|gamma-butyrobetaine hydroxylase activity|gamma-butyrobetaine,2-oxoglutarate dioxygenase activity|butyrobetaine hydroxylase activity|g-butyrobetaine dioxygenase activity|4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|gamma-BBH activity http://purl.obolibrary.org/obo/GO_0008336 GO:0047944 biolink:MolecularActivity obsolete glutamate 1-kinase activity OBSOLETE. Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+). go-plus.json ATP:L-glutamate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047944 GO:0047943 biolink:MolecularActivity glutamate-methylamine ligase activity Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate. EC:6.3.4.12|RHEA:17117|MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN|KEGG_REACTION:R01585 go-plus.json L-glutamate:methylamine ligase (ADP-forming)|gamma-glutamylmethylamide synthetase activity http://purl.obolibrary.org/obo/GO_0047943 GO:0008335 biolink:BiologicalProcess female germline ring canal stabilization Maintenance of the structural integrity of the ring canals connecting the female germline cyst. go-plus.json ovarian ring canal stabilization|nurse cell ring canal stabilization http://purl.obolibrary.org/obo/GO_0008335 GO:0047942 biolink:MolecularActivity glutamate-ethylamine ligase activity Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate. EC:6.3.1.6|MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN|KEGG_REACTION:R02929|RHEA:20525 go-plus.json L-glutamate:ethylamine ligase (ADP-forming)|N(5)-ethyl-L-glutamine synthetase activity|N5-ethylglutamine synthetase activity|N5-ethyl-L-glutamine synthetase activity|theanine synthetase activity http://purl.obolibrary.org/obo/GO_0047942 GO:0008334 biolink:BiologicalProcess histone mRNA metabolic process The chemical reactions and pathways involving an mRNA encoding a histone. go-plus.json histone mRNA metabolism|stem-loop-containing histone mRNA 3'-end processing http://purl.obolibrary.org/obo/GO_0008334 GO:0047941 biolink:MolecularActivity glucuronolactone reductase activity Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH. KEGG_REACTION:R03183|MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN|EC:1.1.1.20|RHEA:18925 go-plus.json http://purl.obolibrary.org/obo/GO_0047941 GO:0008333 biolink:BiologicalProcess endosome to lysosome transport The directed movement of substances from endosomes to lysosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0008333 GO:0047940 biolink:MolecularActivity glucuronokinase activity Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+). RHEA:17005|MetaCyc:GLUCURONOKINASE-RXN|KEGG_REACTION:R01476|EC:2.7.1.43 go-plus.json ATP:D-glucuronate 1-phosphotransferase activity|glucurono-glucuronokinase activity|glucuronokinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0047940 GO:0008332 biolink:MolecularActivity low voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded. go-plus.json T-type calcium channel|low voltage-dependent calcium channel activity|low voltage gated calcium channel activity http://purl.obolibrary.org/obo/GO_0008332 GO:0008331 biolink:MolecularActivity high voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded. go-plus.json P-type calcium channel|Q-type calcium channel|high voltage-dependent calcium channel activity|high voltage gated calcium channel activity|L-type calcium channel|N-type calcium channel http://purl.obolibrary.org/obo/GO_0008331 GO:0008330 biolink:MolecularActivity protein tyrosine/threonine phosphatase activity Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0008330 CHEBI:83586 biolink:ChemicalSubstance N(tele)-phosphonato-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83586 chebi_ph7_3 CHEBI:83585 biolink:ChemicalSubstance N(tele)-phospho-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83585 CHEBI:83583 biolink:ChemicalSubstance 1,1',2-trilinoleoyl-2'-palmitoyl cardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83583 chebi_ph7_3 GO:0047949 biolink:MolecularActivity glutarate-semialdehyde dehydrogenase (NAD+) activity Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH. RHEA:12064|EC:1.2.1.20|MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN go-plus.json glutarate semialdehyde dehydrogenase (NAD+) activity|glutarate-semialdehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047949 CHEBI:83582 biolink:ChemicalSubstance 1,1',2-trilinoleoyl-2'-oleoyl cardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83582 chebi_ph7_3 GO:0047948 biolink:MolecularActivity glutarate-CoA ligase activity Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate. EC:6.2.1.6|RHEA:14169|MetaCyc:GLUTARATE--COA-LIGASE-RXN|KEGG_REACTION:R02402 go-plus.json glutarate:CoA ligase (ADP-forming)|glutaryl-CoA synthetase activity|glutaryl coenzyme A synthetase activity http://purl.obolibrary.org/obo/GO_0047948 CHEBI:83581 biolink:ChemicalSubstance tetralinoleoyl cardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83581 chebi_ph7_3 GO:0047947 biolink:MolecularActivity glutamine N-phenylacetyltransferase activity Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine. MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN|EC:2.3.1.14|RHEA:21844 go-plus.json glutamine phenylacetyltransferase activity|phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity|phenylacetyl-CoA:L-glutamine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047947 CHEBI:83580 biolink:ChemicalSubstance trilinoleoyl 2-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83580 chebi_ph7_3 GO:0047946 biolink:MolecularActivity glutamine N-acyltransferase activity Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine. RHEA:18469|MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN|EC:2.3.1.68 go-plus.json acyl-CoA:L-glutamine N-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047946 GO:0047945 biolink:MolecularActivity L-glutamine:pyruvate aminotransferase activity Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine. Reactome:R-HSA-893616|EC:2.6.1.15|KEGG_REACTION:R00576|RHEA:10400|MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN go-plus.json glutaminase II activity|glutamine-alpha-keto acid transaminase activity|glutamine-keto acid aminotransferase activity|glutamine--oxo-acid transaminase activity|glutamine-alpha-keto acid transamidase activity|glutamine transaminase activity|L-glutamine transaminase L|glutamine--pyruvate aminotransferase activity|gamma-glutaminyltransferase activity|glutamine-pyruvate transaminase activity|glutamine transaminase L activity|glutamine-oxo acid aminotransferase activity http://purl.obolibrary.org/obo/GO_0047945 NCBITaxon:2822797 biolink:OrganismalEntity Stipodae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2822797 GO:0008309 biolink:MolecularActivity double-stranded DNA exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule. go-plus.json double-stranded DNA specific exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0008309 GO:0008308 biolink:MolecularActivity voltage-gated anion channel activity Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Reactome:R-HSA-9012374 go-plus.json voltage-gated ion-selective channel activity|voltage-dependent ion-selective channel activity http://purl.obolibrary.org/obo/GO_0008308 GO:0008307 biolink:MolecularActivity structural constituent of muscle The action of a molecule that contributes to the structural integrity of a muscle fiber. go-plus.json http://purl.obolibrary.org/obo/GO_0008307 GO:0008306 biolink:BiologicalProcess associative learning Learning by associating a stimulus (the cause) with a particular outcome (the effect). Wikipedia:Learning#Associative_learning go-plus.json conditional learning|classical conditioning|Pavlovian conditioning|conditional response http://purl.obolibrary.org/obo/GO_0008306 GO:0008305 biolink:CellularComponent integrin complex A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands. go-plus.json laminin receptor protein http://purl.obolibrary.org/obo/GO_0008305 GO:0008304 biolink:CellularComponent obsolete eukaryotic translation initiation factor 4 complex OBSOLETE. (Was not defined before being made obsolete). go-plus.json eukaryotic translation initiation factor 4 complex|eIF-4 http://purl.obolibrary.org/obo/GO_0008304 GO:0047955 biolink:MolecularActivity glycerol dehydrogenase (acceptor) activity Catalysis of the reaction: A + glycerol = AH(2) + glycerone. EC:1.1.99.22|KEGG_REACTION:R01045|MetaCyc:GLYCEROL-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:17493 go-plus.json glycerol:(acceptor) 1-oxidoreductase activity|glycerol:acceptor 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047955 GO:0008303 biolink:CellularComponent caspase complex A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes. go-plus.json cysteine-type endopeptidase complex http://purl.obolibrary.org/obo/GO_0008303 GO:0047954 biolink:MolecularActivity glycerol-2-phosphatase activity Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate. EC:3.1.3.19|RHEA:13105|MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN|KEGG_REACTION:R01043 go-plus.json glycerol-2-phosphate phosphohydrolase activity|beta-glycerophosphate phosphatase activity|2-glycerophosphatase activity|beta-glycerophosphatase activity http://purl.obolibrary.org/obo/GO_0047954 GO:0008302 biolink:BiologicalProcess female germline ring canal formation, actin assembly Recruitment and organization of actin filaments in female germline ring canals. go-plus.json ring canal formation, actin assembly|ovarian ring canal formation, actin assembly|nurse cell ring canal formation, actin assembly http://purl.obolibrary.org/obo/GO_0008302 GO:0008301 biolink:MolecularActivity DNA binding, bending The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. go-plus.json DNA bending involving DNA binding|DNA bending activity http://purl.obolibrary.org/obo/GO_0008301 GO:0047953 biolink:MolecularActivity glycerol 2-dehydrogenase (NADP+) activity Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH. MetaCyc:GLYCEROL-2-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01039|RHEA:12753|EC:1.1.1.156 go-plus.json dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|dihydroxyacetone reductase activity|glycerol:NADP+ 2-oxidoreductase (glycerone-forming)|DHA oxidoreductase activity|dihydroxyacetone reductase (NADPH) http://purl.obolibrary.org/obo/GO_0047953 GO:0008300 biolink:BiologicalProcess isoprenoid catabolic process The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. go-plus.json isoprenoid catabolism|polyterpene catabolism|polyisoprenoid degradation|polyisoprenoid catabolism|polyisoprenoid breakdown|polyisoprenoid catabolic process|polyterpene catabolic process|isoprenoid degradation|isoprenoid breakdown http://purl.obolibrary.org/obo/GO_0008300 GO:0047952 biolink:MolecularActivity glycerol-3-phosphate dehydrogenase [NAD(P)+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+. KEGG_REACTION:R00844|MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN|EC:1.1.1.94 go-plus.json glycerol-3-phosphate dehydrogenase (NAD(P)+) activity|L-glycerol-3-phosphate:NAD(P) oxidoreductase activity|sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity|glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity http://purl.obolibrary.org/obo/GO_0047952 GO:0047951 biolink:MolecularActivity glutathione thiolesterase activity Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+). RHEA:22708|KEGG_REACTION:R00547|EC:3.1.2.7|MetaCyc:GLUTATHIONE-THIOESTERASE-RXN go-plus.json citryl-glutathione thioesterhydrolase activity|glutathione thioesterase activity|S-acylglutathione hydrolase activity http://purl.obolibrary.org/obo/GO_0047951 GO:0047950 biolink:MolecularActivity glutathione oxidase activity Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2). EC:1.8.3.3|KEGG_REACTION:R00120|RHEA:24112|MetaCyc:GLUTATHIONE-OXIDASE-RXN go-plus.json glutathione:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047950 CHEBI:58596 biolink:ChemicalSubstance coenzyme B(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58596 chebi_ph7_3 CHEBI:58595 biolink:ChemicalSubstance dGDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58595 chebi_ph7_3 CHEBI:58594 biolink:ChemicalSubstance gibberellin A8(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58594 chebi_ph7_3 CHEBI:58593 biolink:ChemicalSubstance dCDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58593 chebi_ph7_3 CHEBI:58592 biolink:ChemicalSubstance 5-amino-1-(5-phosphonato-D-ribosyl)imidazol-3-ium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58592 chebi_ph7_3 GO:0047959 biolink:MolecularActivity glycine dehydrogenase (cytochrome) activity Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c. RHEA:16909|MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.4.2.1 go-plus.json glycine-cytochrome c reductase activity|glycine:ferricytochrome-c oxidoreductase (deaminating)|reductase, glycine-cytochrome c http://purl.obolibrary.org/obo/GO_0047959 CHEBI:58591 biolink:ChemicalSubstance 3-disulfanyl-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58591 chebi_ph7_3 GO:0047958 biolink:MolecularActivity glycine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate. MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN|EC:2.6.1.4|RHEA:14089 go-plus.json glyoxylate-glutamic transaminase activity|glycine aminotransferase activity|glycine transaminase activity|glyoxylate-glutamate aminotransferase activity|glutamic-glyoxylic transaminase activity|glutamate-glyoxylate transaminase activity|L-glutamate:glyoxylate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047958 GO:0047957 biolink:MolecularActivity 4'-methoxyisoflavone 2'-hydroxylase activity Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O. EC:1.14.14.89|RHEA:12388|MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN go-plus.json formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)|isoflavone 2'-monooxygenase activity http://purl.obolibrary.org/obo/GO_0047957 CHEBI:58590 biolink:ChemicalSubstance gibberellin A3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58590 chebi_ph7_3 GO:0047956 biolink:MolecularActivity glycerol dehydrogenase [NADP+] activity Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH. EC:1.1.1.72|MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN|RHEA:23592 go-plus.json glycerol dehydrogenase (NADP+) activity|glycerol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047956 OBO:GOCHE_25212 biolink:OntologyClass substance with metabolite role go-plus.json http://purl.obolibrary.org/obo/GOCHE_25212 3_STAR CHEBI:58599 biolink:ChemicalSubstance N'-phosphonatoguanidinoethyl methyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58599 chebi_ph7_3 GO:0008319 biolink:MolecularActivity obsolete prenyl protein specific endopeptidase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json prenyl protein specific endopeptidase activity http://purl.obolibrary.org/obo/GO_0008319 GO:0008318 biolink:MolecularActivity protein prenyltransferase activity Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0008318 GO:0008317 biolink:MolecularActivity gurken receptor binding Binding to a gurken growth factor receptor. go-plus.json gurken receptor ligand http://purl.obolibrary.org/obo/GO_0008317 GO:0008316 biolink:MolecularActivity structural constituent of vitelline membrane The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0008316 GO:0008315 biolink:BiologicalProcess G2/MI transition of meiotic cell cycle The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I. go-plus.json meiotic G2/MI transition|meiotic cell cycle G2/MI phase transition|meiotic G2/MI phase transition http://purl.obolibrary.org/obo/GO_0008315 GO:0047966 biolink:MolecularActivity glycosulfatase activity Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate. EC:3.1.6.3|RHEA:19145|MetaCyc:GLYCOSULFATASE-RXN|KEGG_REACTION:R00534 go-plus.json glycosulphatase activity|sugar-sulfate sulfohydrolase activity|glucosulfatase activity http://purl.obolibrary.org/obo/GO_0047966 GO:0008314 biolink:BiologicalProcess gurken signaling pathway The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to a ligand Gurken. go-plus.json signaling by Gurken|gurken receptor signalling pathway|gurken receptor signaling pathway|gurken-activated signaling pathway http://purl.obolibrary.org/obo/GO_0008314 GO:0008313 biolink:MolecularActivity gurken-activated receptor activity Combining with the ligand Gurken to initiate a change in cell activity. go-plus.json gurken receptor activity http://purl.obolibrary.org/obo/GO_0008313 GO:0047965 biolink:MolecularActivity glycoprotein O-fatty-acyltransferase activity Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein. EC:2.3.1.142|MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN go-plus.json protein acyltransferase activity|fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047965 GO:0047964 biolink:MolecularActivity glyoxylate reductase (NAD+) activity Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH. MetaCyc:GLYCOLATE-REDUCTASE-RXN|EC:1.1.1.26|RHEA:18229 go-plus.json glycolate reductase activity|glyoxylic acid reductase activity|NADH-dependent glyoxylate reductase activity http://purl.obolibrary.org/obo/GO_0047964 GO:0008312 biolink:MolecularActivity 7S RNA binding Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP). go-plus.json http://purl.obolibrary.org/obo/GO_0008312 GO:0047963 biolink:MolecularActivity glycine N-choloyltransferase activity Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate. RHEA:14001|MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN|EC:2.3.1.65 go-plus.json bile acid-CoA:amino acid N-acyltransferase activity|amino acid N-choloyltransferase activity|choloyl-CoA:glycine N-choloyltransferase activity|cholyl-CoA glycine-taurine N-acyltransferase activity|cholyl-CoA:taurine N-acyltransferase activity|BAT activity|BACAT activity|glycine--taurine N-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047963 GO:0008311 biolink:MolecularActivity double-stranded DNA 3'-5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule. go-plus.json double-stranded DNA specific 3'-5' exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0008311 GO:0047962 biolink:MolecularActivity glycine N-benzoyltransferase activity Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+). RHEA:18493|MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN|Reactome:R-HSA-159574|EC:2.3.1.71|KEGG_REACTION:R02452|Reactome:R-HSA-159566 go-plus.json benzoyl CoA-amino acid N-acyltransferase activity|benzoyl-CoA:glycine N-benzoyltransferase activity|benzoyl-CoA:glycine N-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047962 GO:0008310 biolink:MolecularActivity single-stranded DNA 3'-5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule. go-plus.json single-stranded DNA specific 3'-5' exodeoxyribonuclease activity|ssDNA-specific 3'-5' exodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0008310 GO:0047961 biolink:MolecularActivity glycine N-acyltransferase activity Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine. MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN|EC:2.3.1.13|Reactome:R-HSA-2534040|RHEA:19869 go-plus.json glycine-N-acylase activity|glycine acyltransferase activity|acyl-CoA:glycine N-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047961 GO:0047960 biolink:MolecularActivity glycine dehydrogenase activity Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH. MetaCyc:GLYCINE-DEHYDROGENASE-RXN|EC:1.4.1.10|RHEA:15721 go-plus.json glycine:NAD+ oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0047960 CHEBI:58585 biolink:ChemicalSubstance L-allothreonine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58585 chebi_ph7_3 CHEBI:58584 biolink:ChemicalSubstance 20-hydroxy-leukotriene E4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58584 chebi_ph7_3 CHEBI:58583 biolink:ChemicalSubstance 4-acetamidobutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58583 chebi_ph7_3 CHEBI:58582 biolink:ChemicalSubstance UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58582 chebi_ph7_3 CHEBI:58581 biolink:ChemicalSubstance precorrin-8X(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58581 chebi_ph7_3 GO:0047969 biolink:MolecularActivity glyoxylate oxidase activity Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate. EC:1.2.3.5|Reactome:R-HSA-389862|MetaCyc:GLYOXYLATE-OXIDASE-RXN|RHEA:14837|KEGG_REACTION:R00466 go-plus.json glyoxylate:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047969 CHEBI:58580 biolink:ChemicalSubstance tetrahydrofolyl-poly(glutamate) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_58580 chebi_ph7_3 GO:0047968 biolink:MolecularActivity glyoxylate dehydrogenase (acylating) activity Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA. MetaCyc:GLYOXYLATE-DEHYDROGENASE-ACYLATING-RXN|EC:1.2.1.17|KEGG_REACTION:R00468|RHEA:21024 go-plus.json glyoxylate:NADP+ oxidoreductase (CoA-oxalylating) http://purl.obolibrary.org/obo/GO_0047968 GO:0047967 biolink:MolecularActivity glycyrrhizinate beta-glucuronidase activity Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate. RHEA:17369|MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN|EC:3.2.1.128|KEGG_REACTION:R03906 go-plus.json glycyrrhizinate glucuronosylhydrolase activity|glycyrrhizinate b-glucuronidase activity|glycyrrhizin beta-hydrolase activity|glycyrrhizinic acid hydrolase activity|glycyrrhizin hydrolase activity http://purl.obolibrary.org/obo/GO_0047967 CHEBI:58589 biolink:ChemicalSubstance pyridoxine 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58589 chebi_ph7_3 CHEBI:58588 biolink:ChemicalSubstance flavonol oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58588 CHEBI:58587 biolink:ChemicalSubstance gibberellin A19(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58587 chebi_ph7_3 CHEBI:58586 biolink:ChemicalSubstance 4-hydroxyphenylglyoxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58586 chebi_ph7_3 GO:0047977 biolink:MolecularActivity hepoxilin-epoxide hydrolase activity Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate. Reactome:R-HSA-2161949|EC:3.3.2.7|RHEA:16665|MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN go-plus.json (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity|hepoxilin A3 hydrolase activity|hepoxylin hydrolase activity|hepoxilin A(3) hydrolase activity|hepoxilin epoxide hydrolase activity http://purl.obolibrary.org/obo/GO_0047977 GO:0047976 biolink:MolecularActivity hamamelose kinase activity Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+). KEGG_REACTION:R03766|RHEA:22796|EC:2.7.1.102|MetaCyc:HAMAMELOSE-KINASE-RXN go-plus.json hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)|ATP:D-hamamelose 2'-phosphotransferase activity|ATP/hamamelose 2'-phosphotransferase activity|hamamelose kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0047976 GO:0047975 biolink:MolecularActivity guanosine phosphorylase activity Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate. EC:2.4.2.15|RHEA:13233|MetaCyc:GUANPHOSPHOR-RXN go-plus.json guanosine:phosphate alpha-D-ribosyltransferase activity|guanosine:phosphate D-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0047975 GO:0047974 biolink:MolecularActivity guanosine deaminase activity Catalysis of the reaction: guanosine + H2O = xanthosine + NH3. EC:3.5.4.15|RHEA:12861|MetaCyc:GUANOSINE-DEAMINASE-RXN go-plus.json guanosine aminohydrolase activity|guanosine aminase activity http://purl.obolibrary.org/obo/GO_0047974 GO:0047973 biolink:MolecularActivity guanidinoacetate kinase activity Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate. MetaCyc:GUANIDOACETATE-KINASE-RXN|KEGG_REACTION:R02575|RHEA:14145|EC:2.7.3.1 go-plus.json guanidoacetate kinase activity|ATP:guanidinoacetate N-phosphotransferase activity|glycocyamine kinase activity http://purl.obolibrary.org/obo/GO_0047973 GO:0047972 biolink:MolecularActivity guanidinopropionase activity Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea. EC:3.5.3.17|MetaCyc:GUANIDINOPROPIONASE-RXN|RHEA:16029|KEGG_REACTION:R00913 go-plus.json 3-guanidinopropanoate amidinopropionase activity|GPase activity|GPH http://purl.obolibrary.org/obo/GO_0047972 GO:0047971 biolink:MolecularActivity guanidinobutyrase activity Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea. EC:3.5.3.7|KEGG_REACTION:R01990|RHEA:19501|MetaCyc:GUANIDINOBUTYRASE-RXN go-plus.json 4-guanidinobutanoate amidinohydrolase activity|GBH|guanidinobutyrate ureahydrolase activity|gamma-guanidobutyrase activity|gamma-guanidinobutyrate amidinohydrolase activity|4-guanidinobutyrate amidinobutyrase activity|G-base activity http://purl.obolibrary.org/obo/GO_0047971 GO:0047970 biolink:MolecularActivity guanidinoacetase activity Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea. KEGG_REACTION:R00775|RHEA:23268|EC:3.5.3.2|MetaCyc:GUANIDINOACETASE-RXN go-plus.json guanidinoacetate amidinohydrolase activity|glycocyaminase activity http://purl.obolibrary.org/obo/GO_0047970 CHEBI:58574 biolink:ChemicalSubstance 4-hydroxybutyryl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58574 chebi_ph7_3 CHEBI:58573 biolink:ChemicalSubstance kaempferol oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58573 chebi_ph7_3 CHEBI:58572 biolink:ChemicalSubstance N-[(5S)-5-ammonio-5-carboxylatopentanoyl]-L-cysteinyl-D-valinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58572 chebi_ph7_3 CHEBI:58571 biolink:ChemicalSubstance 5-methylbarbituride go-plus.json http://purl.obolibrary.org/obo/CHEBI_58571 chebi_ph7_3 CHEBI:58570 biolink:ChemicalSubstance D-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58570 chebi_ph7_3 GO:0047979 biolink:MolecularActivity hexose oxidase activity Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202. MetaCyc:HEXOSE-OXIDASE-RXN|EC:1.1.3.5 go-plus.json D-hexose:oxygen 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047979 GO:0047978 biolink:MolecularActivity hexadecanol dehydrogenase activity Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH. MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN|RHEA:22056|EC:1.1.1.164 go-plus.json hexadecanol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047978 CHEBI:58579 biolink:ChemicalSubstance beta-D-fructofuranose 2,6-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58579 chebi_ph7_3 CHEBI:58578 biolink:ChemicalSubstance UDP-N-acetyl-D-mannosaminouronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58578 chebi_ph7_3 CHEBI:58577 biolink:ChemicalSubstance biochanin A 7-O-beta-D-glucoside 6''-O-malonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58577 CHEBI:58576 biolink:ChemicalSubstance 2-deoxy-D-ribofuranose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58576 chebi_ph7_3 CHEBI:58575 biolink:ChemicalSubstance cob(I)yrinate a,c diamide(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58575 chebi_ph7_3 GO:0047980 biolink:MolecularActivity hippurate hydrolase activity Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine. KEGG_REACTION:R01424|RHEA:10424|EC:3.5.1.32|MetaCyc:HIPPURATE-HYDROLASE-RXN go-plus.json N-benzoylamino-acid amidohydrolase activity|benzoylglycine amidohydrolase activity|hippuricase activity http://purl.obolibrary.org/obo/GO_0047980 GO:0047988 biolink:MolecularActivity hydroxyacid-oxoacid transhydrogenase activity Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate. Reactome:R-HSA-880002|MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN|EC:1.1.99.24|Reactome:R-HSA-880033 go-plus.json (S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity|transhydrogenase, hydroxy acid-oxo acid http://purl.obolibrary.org/obo/GO_0047988 GO:0047987 biolink:MolecularActivity hydroperoxide dehydratase activity Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O. RHEA:25075|MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN|EC:4.2.1.92 go-plus.json HPI|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|linoleic acid hydroperoxide isomerase|hydroperoxide isomerase activity|linoleate hydroperoxide isomerase|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047987 GO:0047986 biolink:MolecularActivity hydrogen-sulfide S-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate. EC:2.3.1.10|KEGG_REACTION:R01850|RHEA:16625|MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN go-plus.json acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity|hydrogen-sulphide S-acetyltransferase activity|hydrogen-sulfide acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047986 GO:0047985 biolink:MolecularActivity hydrogen dehydrogenase activity Catalysis of the reaction: H2 + NAD+ = H+ + NADH. EC:1.12.1.2|MetaCyc:HYDROGEN-DEHYDROGENASE-RXN|RHEA:24636 go-plus.json hydrogenase activity|H(2):NAD(+) oxidoreductase activity|bidirectional hydrogenase activity|hydrogen:NAD+ oxidoreductase activity|NAD-linked hydrogenase activity|H2:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047985 GO:0047984 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047984 GO:0047983 biolink:MolecularActivity homoglutathione synthase activity Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate. MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN|EC:6.3.2.23|KEGG_REACTION:R02741|RHEA:17993 go-plus.json beta-alanine specific hGSH synthetase activity|gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)|homoglutathione synthetase activity http://purl.obolibrary.org/obo/GO_0047983 GO:0047982 biolink:MolecularActivity homocysteine desulfhydrase activity Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate. MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN|RHEA:14501|Reactome:R-HSA-1614631|EC:4.4.1.2 go-plus.json homocysteine desulfurase activity|L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)|L-homocysteine hydrogen-sulfide-lyase (deaminating) http://purl.obolibrary.org/obo/GO_0047982 GO:0047981 biolink:MolecularActivity histidine N-acetyltransferase activity Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+). EC:2.3.1.33|RHEA:24596|KEGG_REACTION:R01160|MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN go-plus.json acetylhistidine synthetase activity|acetyl-CoA:L-histidine N-acetyltransferase activity|histidine acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047981 CHEBI:58563 biolink:ChemicalSubstance (R)-1-ammoniopropan-2-yl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58563 chebi_ph7_3 CHEBI:58562 biolink:ChemicalSubstance all-cis-5,8,11,14,17-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58562 chebi_ph7_3 CHEBI:58561 biolink:ChemicalSubstance precorrin-3A(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58561 chebi_ph7_3 CHEBI:58560 biolink:ChemicalSubstance L-alpha-glutamyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58560 chebi_ph7_3 GO:0047989 biolink:MolecularActivity hydroxybutyrate-dimer hydrolase activity Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+). RHEA:10172|MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN|EC:3.1.1.22|KEGG_REACTION:R00048 go-plus.json (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity|D-(-)-3-hydroxybutyrate-dimer hydrolase activity http://purl.obolibrary.org/obo/GO_0047989 CHEBI:58567 biolink:ChemicalSubstance ajmalinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58567 chebi_ph7_3 CHEBI:58566 biolink:ChemicalSubstance D-arabinitol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58566 chebi_ph7_3 PR:000019036 biolink:Protein amyloid-beta precursor protein proteolytic cleavage product An amyloid-beta precursor protein that has been processed by proteolytic cleavage. go-plus.json APP/ClvPrd http://purl.obolibrary.org/obo/PR_000019036 CHEBI:58565 biolink:ChemicalSubstance 5-hydroxyimidazole-4-acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58565 chebi_ph7_3 CHEBI:58564 biolink:ChemicalSubstance 5-amino-1-(5-phosphonato-D-ribosyl)imidazole-4-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58564 GO:0047991 biolink:MolecularActivity hydroxylamine oxidase activity Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite. MetaCyc:HAONITRO-RXN|RHEA:19969|KEGG_REACTION:R00793|EC:1.7.3.6 go-plus.json hydroxylamine:oxygen oxidoreductase activity|HAO|hydroxylamine oxidoreductase http://purl.obolibrary.org/obo/GO_0047991 GO:0047990 biolink:MolecularActivity hydroxyglutamate decarboxylase activity Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2). KEGG_REACTION:R04135|RHEA:14073|MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN|EC:4.1.1.16 go-plus.json 3-hydroxy-L-glutamate 1-carboxy-lyase activity|3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming) http://purl.obolibrary.org/obo/GO_0047990 NCBITaxon:1304792 biolink:OrganismalEntity Tenebrionidae incertae sedis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1304792 GO:0047999 biolink:MolecularActivity hyponitrite reductase activity Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH. MetaCyc:HYPONITRITE-REDUCTASE-RXN|KEGG_REACTION:R00023|EC:1.7.1.5|RHEA:19337 go-plus.json NADH2:hyponitrite oxidoreductase activity|NADH:hyponitrite oxidoreductase activity|hydroxylamine:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047999 GO:0047998 biolink:MolecularActivity hyoscyamine (6S)-dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate. KEGG_REACTION:R03812|MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN|EC:1.14.11.11|RHEA:12629 go-plus.json hyoscyamine 6beta-dioxygenase activity|hyoscyamine 6beta-hydroxylase activity|hyoscyamine (6S)-hydroxylase activity|L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)|hyoscyamine 6-beta-hydroxylase activity|hyoscyamine 6-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047998 GO:0047997 biolink:MolecularActivity hydroxypyruvate decarboxylase activity Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde. EC:4.1.1.40|RHEA:20561|KEGG_REACTION:R01393|MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN go-plus.json hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)|hydroxypyruvate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0047997 GO:0047996 biolink:MolecularActivity hydroxyphytanate oxidase activity Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2). MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN|RHEA:21680|KEGG_REACTION:R07151|EC:1.1.3.27 go-plus.json L-2-hydroxyphytanate:oxygen 2-oxidoreductase http://purl.obolibrary.org/obo/GO_0047996 UBERON:2001431 biolink:AnatomicalEntity primitive olfactory epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_2001431 GO:0047995 biolink:MolecularActivity hydroxyphenylpyruvate reductase activity Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH. RHEA:10780|MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN|EC:1.1.1.237 go-plus.json HPRP|4-hydroxyphenyllactate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047995 GO:0047994 biolink:MolecularActivity hydroxymethylglutaryl-CoA hydrolase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+). RHEA:16305|EC:3.1.2.5|KEGG_REACTION:R02083|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN go-plus.json (S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity|hydroxymethylglutaryl coenzyme A hydrolase activity|hydroxymethylglutaryl coenzyme A deacylase activity|3-hydroxy-3-methylglutaryl-CoA hydrolase activity|beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity|beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity http://purl.obolibrary.org/obo/GO_0047994 GO:0047993 biolink:MolecularActivity hydroxymalonate dehydrogenase activity Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate. RHEA:11284|EC:1.1.1.167|MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN|KEGG_REACTION:R02969 go-plus.json hydroxymalonate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047993 GO:0047992 biolink:MolecularActivity hydroxylysine kinase activity Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+). KEGG_REACTION:R03378|RHEA:19049|EC:2.7.1.81|MetaCyc:HYDROXYLYSINE-KINASE-RXN|Reactome:R-HSA-6788611 go-plus.json hydroxylysine kinase (phosphorylating)|guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity|GTP:5-hydroxy-L-lysine O-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047992 CHEBI:58552 biolink:ChemicalSubstance N(2')-acetylgentamycin C1a(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58552 chebi_ph7_3 CHEBI:34584 biolink:ChemicalSubstance boldenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_34584 chebi_ph7_3 CHEBI:58550 biolink:ChemicalSubstance N(1),N(12)-diacetylsperminium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58550 chebi_ph7_3 CHEBI:58558 biolink:ChemicalSubstance N-benzyloxycarbonyl-L-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58558 chebi_ph7_3 CHEBI:58557 biolink:ChemicalSubstance N-acetyl-D-mannosamine 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58557 chebi_ph7_3 CHEBI:58556 biolink:ChemicalSubstance (S)-2-amino-6-oxopimelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58556 chebi_ph7_3 CHEBI:58555 biolink:ChemicalSubstance S-acetylphosphopantotheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58555 chebi_ph7_3 CHEBI:58554 biolink:ChemicalSubstance gibberellin A44(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58554 chebi_ph7_3 CHEBI:58553 biolink:ChemicalSubstance 5beta,9alpha,10alpha-labda-8(20),13-dien-15-yl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58553 chebi_ph7_3 PR:000019005 biolink:Protein serum amyloid P-component proteolytic cleavage product A serum amyloid P-component that has been processed by proteolytic cleavage. go-plus.json APCS/ClvPrd http://purl.obolibrary.org/obo/PR_000019005 CHEBI:34596 biolink:ChemicalSubstance (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_34596 chebi_ph7_3 CHEBI:58541 biolink:ChemicalSubstance 5-methyldeoxycytidine 5'-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58541 chebi_ph7_3 CHEBI:58540 biolink:ChemicalSubstance (Kdo)2-lipid A(6-) (E. coli) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58540 chebi_ph7_3 NCBITaxon:1798711 biolink:OrganismalEntity Cyanobacteria/Melainabacteria group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1798711 CHEBI:34597 biolink:ChemicalSubstance (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_34597 chebi_ph7_3 CHEBI:58549 biolink:ChemicalSubstance kanamycin B(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58549 chebi_ph7_3 CHEBI:58548 biolink:ChemicalSubstance S-methyl-5-thio-D-ribulose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58548 chebi_ph7_3 PR:000019010 biolink:Protein apolipoprotein A-I proteolytic cleavage product An apolipoprotein A-I that has been processed by proteolytic cleavage. go-plus.json APOA1/ClvPrd http://purl.obolibrary.org/obo/PR_000019010 CHEBI:58547 biolink:ChemicalSubstance N-hydroxy-L-tyrosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58547 chebi_ph7_3 CHEBI:58546 biolink:ChemicalSubstance cyanidin 3-O-rutinoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58546 chebi_ph7_3 CHEBI:58544 biolink:ChemicalSubstance 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58544 chebi_ph7_3 CHEBI:58543 biolink:ChemicalSubstance cis-dodec-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58543 chebi_ph7_3 CHEBI:58542 biolink:ChemicalSubstance D-arabino-hex-3-ulose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58542 chebi_ph7_3 GO:0033361 biolink:BiologicalProcess lysine biosynthetic process via diaminopimelate, dehydrogenase pathway The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step. MetaCyc:PWY-2942 go-plus.json lysine biosynthesis via diaminopimelic acid, dehydrogenase pathway|lysine formation via diaminopimelate, dehydrogenase pathway|lysine synthesis via diaminopimelate, dehydrogenase pathway|lysine anabolism via diaminopimelate, dehydrogenase pathway http://purl.obolibrary.org/obo/GO_0033361 GO:0033360 biolink:BiologicalProcess lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps. MetaCyc:PWY-2941 go-plus.json lysine biosynthetic process via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine biosynthesis via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine formation via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine synthesis via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine anabolism via diaminopimelate and L-2-acetamido-6-oxoheptanedioate http://purl.obolibrary.org/obo/GO_0033360 GO:0033369 biolink:BiologicalProcess establishment of protein localization to mast cell secretory granule The directed movement of a protein to a location within a secretory granule in a mast cell. go-plus.json establishment of protein localisation in mast cell secretory granule|establishment of protein localization in mast cell secretory granule http://purl.obolibrary.org/obo/GO_0033369 CHEBI:138067 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138067 chebi_ph7_3 GO:0033368 biolink:BiologicalProcess protease localization to mast cell secretory granule Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell. go-plus.json protease localization in mast cell secretory granule|protease localisation in mast cell secretory granule http://purl.obolibrary.org/obo/GO_0033368 GO:0033367 biolink:BiologicalProcess protein localization to mast cell secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell. go-plus.json protein localisation in mast cell secretory granule|protein localization in mast cell secretory granule http://purl.obolibrary.org/obo/GO_0033367 GO:0033366 biolink:BiologicalProcess protein localization to secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule. go-plus.json protein localization in secretory granule|protein localisation in secretory granule http://purl.obolibrary.org/obo/GO_0033366 GO:0033365 biolink:BiologicalProcess protein localization to organelle A process in which a protein is transported to, or maintained in, a location within an organelle. go-plus.json protein localisation to organelle|protein localization in organelle http://purl.obolibrary.org/obo/GO_0033365 GO:0033364 biolink:BiologicalProcess mast cell secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. go-plus.json mast cell secretory granule organisation|mast cell secretory granule maturation|mast cell secretory granule organization and biogenesis http://purl.obolibrary.org/obo/GO_0033364 GO:0033363 biolink:BiologicalProcess secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. go-plus.json secretory granule organization and biogenesis|secretory granule organisation http://purl.obolibrary.org/obo/GO_0033363 GO:0033362 biolink:BiologicalProcess lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps. MetaCyc:PWY-5097 go-plus.json lysine formation via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine biosynthesis via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine anabolism via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine synthesis via diaminopimelate, diaminopimelate-aminotransferase pathway http://purl.obolibrary.org/obo/GO_0033362 CHEBI:138068 biolink:ChemicalSubstance ribonucleoside 5'-diphosphate-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138068 chebi_ph7_3 GO:0033359 biolink:BiologicalProcess lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps. MetaCyc:DAPLYSINESYN-PWY go-plus.json lysine synthesis via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine formation via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine biosynthetic process via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine biosynthesis via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine anabolism via diaminopimelate and N-succinyl-2-amino-6-ketopimelate http://purl.obolibrary.org/obo/GO_0033359 GO:0033350 biolink:BiologicalProcess apiose biosynthetic process The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose. go-plus.json apiose anabolism|apiose synthesis|apiose formation|apiose biosynthesis http://purl.obolibrary.org/obo/GO_0033350 CHEBI:138078 biolink:ChemicalSubstance 5'-(N(2),N(7)-dimethyl 5'-triphosphoguanosine)-(purine ribonucleotide)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138078 chebi_ph7_3 GO:0033358 biolink:BiologicalProcess UDP-L-arabinose biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-63|MetaCyc:PWY-82 go-plus.json UDP-L-arabinose anabolism|UDP-L-arabinose synthesis|UDP-L-arabinose biosynthesis|UDP-L-arabinose formation http://purl.obolibrary.org/obo/GO_0033358 GO:0033357 biolink:BiologicalProcess L-arabinose biosynthetic process The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose. go-plus.json L-arabinose biosynthesis|L-arabinose anabolism|L-arabinose synthesis|L-arabinose formation http://purl.obolibrary.org/obo/GO_0033357 CHEBI:138077 biolink:ChemicalSubstance chloroxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_138077 chebi_ph7_3 CHEBI:138076 biolink:ChemicalSubstance 1,1'-dihydroxyneurosporene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138076 chebi_ph7_3 GO:0033356 biolink:BiologicalProcess UDP-L-arabinose metabolic process The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate. go-plus.json UDP-L-arabinose metabolism http://purl.obolibrary.org/obo/GO_0033356 CHEBI:138075 biolink:ChemicalSubstance 5-formyl CMP(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138075 chebi_ph7_3 GO:0033355 biolink:BiologicalProcess ascorbate glutathione cycle A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH. MetaCyc:PWY-2261 go-plus.json hydrogen peroxide detoxification http://purl.obolibrary.org/obo/GO_0033355 GO:0033354 biolink:BiologicalProcess chlorophyll cycle A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates. MetaCyc:PWY-5068 go-plus.json http://purl.obolibrary.org/obo/GO_0033354 GO:0033353 biolink:BiologicalProcess S-adenosylmethionine cycle A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine. MetaCyc:PWY-5041 go-plus.json activated methyl cycle|SAM cycle http://purl.obolibrary.org/obo/GO_0033353 GO:0033352 biolink:BiologicalProcess UDP-D-apiose biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-4821|MetaCyc:PWY-5113 go-plus.json UDP-D-apiose anabolism|UDP-D-apiose biosynthesis|UDP-D-apiose synthesis|UDP-D-apiose formation http://purl.obolibrary.org/obo/GO_0033352 CHEBI:138079 biolink:ChemicalSubstance 5'-(N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-(purine ribonucleotide)(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138079 chebi_ph7_3 GO:0033351 biolink:BiologicalProcess UDP-D-apiose metabolic process The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate. go-plus.json UDP-D-apiose metabolism http://purl.obolibrary.org/obo/GO_0033351 CHEBI:138052 biolink:ChemicalSubstance (3S)-3,4-dihydroxy-L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138052 chebi_ph7_3 CHEBI:138051 biolink:ChemicalSubstance selina-4(15),7(11)-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138051 chebi_ph7_3 CHEBI:138050 biolink:ChemicalSubstance pseudolaratriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138050 chebi_ph7_3 GO:0033349 biolink:BiologicalProcess apiose metabolic process The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose. go-plus.json apiose metabolism http://purl.obolibrary.org/obo/GO_0033349 GO:0033348 biolink:BiologicalProcess tetrose biosynthetic process The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule. go-plus.json tetrose anabolism|tetrose synthesis|tetrose formation|tetrose biosynthesis http://purl.obolibrary.org/obo/GO_0033348 GO:0008389 biolink:MolecularActivity coumarin 7-hydroxylase activity Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+. Reactome:R-HSA-211881|Reactome:R-HSA-76453 go-plus.json cytochrome P450 CYP2A5 http://purl.obolibrary.org/obo/GO_0008389 GO:0008388 biolink:MolecularActivity testosterone 15-alpha-hydroxylase activity Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O. go-plus.json cytochrome P450 CYP2A4 http://purl.obolibrary.org/obo/GO_0008388 GO:0008387 biolink:MolecularActivity steroid 7-alpha-hydroxylase activity Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O. go-plus.json cytochrome P450 CYP2A12 http://purl.obolibrary.org/obo/GO_0008387 GO:0008386 biolink:MolecularActivity cholesterol monooxygenase (side-chain-cleaving) activity Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O. Reactome:R-HSA-193101|MetaCyc:1.14.15.6-RXN|EC:1.14.15.6|Reactome:R-HSA-193054|RHEA:35739|Reactome:R-HSA-193065 go-plus.json enzymes, cholesterol side-chain-cleaving|cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)|cytochrome P-450(scc) activity|cholesterol C20-22 desmolase activity|cytochrome P-450scc|cytochrome p450(scc) activity|cholesterol side-chain-cleaving enzyme activity|C27-side chain cleavage enzyme|cholesterol desmolase activity|steroid 20-22-lyase activity|cholesterol 20-22-desmolase activity|cholesterol C(20-22) desmolase activity|steroid 20-22 desmolase activity|Cyp11a1|cholesterol side-chain cleavage enzyme activity|cytochrome p450scc|desmolase, steroid 20-22 http://purl.obolibrary.org/obo/GO_0008386 GO:0008385 biolink:CellularComponent IkappaB kinase complex A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. go-plus.json heterotrimeric IKK complex|IKK complex|trimeric IKK complex http://purl.obolibrary.org/obo/GO_0008385 GO:0008384 biolink:MolecularActivity IkappaB kinase activity Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein. MetaCyc:2.7.11.10-RXN|EC:2.7.11.10|RHEA:19073|Reactome:R-HSA-5684275|Reactome:R-HSA-5684267 go-plus.json IKBKB|IKBKA|TBK1|inhibitor of NFkappaB kinase activity|IKK-2|IKK-1|ikappaB kinase activity|STK12|IKK|ATP:IkappaB protein phosphotransferase activity|TANK-binding kinase 1 activity|inhibitor of NF-kappaB kinase activity|CHUK http://purl.obolibrary.org/obo/GO_0008384 GO:0008394 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008394 GO:0008393 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008393 GO:0008392 biolink:MolecularActivity arachidonic acid epoxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid. Reactome:R-HSA-211983 go-plus.json cytochrome P450 CYP2J6|cytochrome P450 CYP2J5 http://purl.obolibrary.org/obo/GO_0008392 GO:0008391 biolink:MolecularActivity arachidonic acid monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water. go-plus.json cytochrome P450 CYP2B19 http://purl.obolibrary.org/obo/GO_0008391 GO:0008390 biolink:MolecularActivity testosterone 16-alpha-hydroxylase activity Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O. go-plus.json cytochrome P450 CYP2D11|cytochrome P450 CYP2D10|cytochrome P450 CYP2B10|cytochrome P450 CYP2B9|cytochrome P450 CYP2D9 http://purl.obolibrary.org/obo/GO_0008390 GO:0033347 biolink:BiologicalProcess tetrose metabolic process The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule. go-plus.json tetrose metabolism http://purl.obolibrary.org/obo/GO_0033347 CHEBI:138045 biolink:ChemicalSubstance (-)-10-epi-cubebol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138045 chebi_ph7_3 GO:0033346 biolink:BiologicalProcess asparagine catabolic process via 2-oxosuccinamate The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate. MetaCyc:PWY-4002 go-plus.json http://purl.obolibrary.org/obo/GO_0033346 CHEBI:138044 biolink:ChemicalSubstance (2Z,6E)-hedycaryol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138044 chebi_ph7_3 GO:0033345 biolink:BiologicalProcess asparagine catabolic process via L-aspartate The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate. MetaCyc:ASPARAGINE-DEG1-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0033345 CHEBI:138043 biolink:ChemicalSubstance (2E,6E)-hedycaryol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138043 chebi_ph7_3 GO:0033344 biolink:BiologicalProcess cholesterol efflux The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. go-plus.json cholesterol export http://purl.obolibrary.org/obo/GO_0033344 CHEBI:138042 biolink:ChemicalSubstance tau-cadinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138042 chebi_ph7_3 GO:0033343 biolink:BiologicalProcess positive regulation of collagen binding Any process that activates or increases the frequency, rate or extent of collagen binding. go-plus.json upregulation of collagen binding|stimulation of collagen binding|up-regulation of collagen binding|activation of collagen binding|up regulation of collagen binding http://purl.obolibrary.org/obo/GO_0033343 CHEBI:138049 biolink:ChemicalSubstance guaia-4,6-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138049 chebi_ph7_3 GO:0033342 biolink:BiologicalProcess negative regulation of collagen binding Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding. go-plus.json down regulation of collagen binding|inhibition of collagen binding|down-regulation of collagen binding|downregulation of collagen binding http://purl.obolibrary.org/obo/GO_0033342 CHEBI:138048 biolink:ChemicalSubstance stellata-2,6,19-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138048 chebi_ph7_3 GO:0033341 biolink:BiologicalProcess regulation of collagen binding Any process that modulates the frequency, rate or extent of collagen binding. go-plus.json http://purl.obolibrary.org/obo/GO_0033341 CHEBI:138047 biolink:ChemicalSubstance beta-thujene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138047 chebi_ph7_3 GO:0033340 biolink:BiologicalProcess pelvic fin development The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0033340 CHEBI:138046 biolink:ChemicalSubstance sesterfisherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138046 chebi_ph7_3 CHEBI:138063 biolink:ChemicalSubstance coelenterazine h dioxetanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_138063 chebi_ph7_3 GO:0033339 biolink:BiologicalProcess pectoral fin development The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0033339 CHEBI:138062 biolink:ChemicalSubstance N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138062 chebi_ph7_3 GO:0033338 biolink:BiologicalProcess medial fin development The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure. go-plus.json median fin development http://purl.obolibrary.org/obo/GO_0033338 CHEBI:138061 biolink:ChemicalSubstance N-terminal L-seryl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138061 chebi_ph7_3 GO:0033337 biolink:BiologicalProcess dorsal fin development The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0033337 CHEBI:138060 biolink:ChemicalSubstance N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138060 chebi_ph7_3 GO:0008399 biolink:MolecularActivity naphthalene hydroxylase activity Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide. go-plus.json cytochrome P450 CYP2F2 http://purl.obolibrary.org/obo/GO_0008399 GO:0008398 biolink:MolecularActivity sterol 14-demethylase activity Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O. RHEA:14917|EC:1.14.13.70|Reactome:R-HSA-194678|MetaCyc:1.14.13.70-RXN go-plus.json sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)|cytochrome P450 CYP51|cytochrome P450 51 activity|lanosterol 14-demethylase activity|lanosterol 14alpha-demethylase activity|obtusufoliol 14-demethylase activity|sterol 14alpha-demethylase activity|lanosterol 14-alpha-demethylase activity|sterol 14-alpha-demethylase activity http://purl.obolibrary.org/obo/GO_0008398 GO:0008397 biolink:MolecularActivity sterol 12-alpha-hydroxylase activity Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O. go-plus.json cytochrome P450 CYP8B1 http://purl.obolibrary.org/obo/GO_0008397 GO:0008396 biolink:MolecularActivity oxysterol 7-alpha-hydroxylase activity Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O. Reactome:R-HSA-191972|Reactome:R-HSA-192178|Reactome:R-HSA-5602885|Reactome:R-HSA-192065 go-plus.json cytochrome P450 CYP7B1 http://purl.obolibrary.org/obo/GO_0008396 GO:0008395 biolink:MolecularActivity steroid hydroxylase activity Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2. Reactome:R-HSA-5602170|Reactome:R-HSA-5601849|RHEA:43836|Reactome:R-HSA-193792|Reactome:R-HSA-193143|Reactome:R-HSA-193460|Reactome:R-HSA-193965|Reactome:R-HSA-192042|Reactome:R-HSA-191983|Reactome:R-HSA-192054|Reactome:R-HSA-192123|Reactome:R-HSA-6785244|Reactome:R-HSA-193393|Reactome:R-HSA-193713|Reactome:R-HSA-193737|Reactome:R-HSA-193780|Reactome:R-HSA-191999|Reactome:R-HSA-6785245|Reactome:R-HSA-193497|Reactome:R-HSA-193995|Reactome:R-HSA-193719|Reactome:R-HSA-193060|Reactome:R-HSA-9035960|Reactome:R-HSA-193787 go-plus.json cytochrome P450 CYP2G1|olfactory-specific steroid hydroxylase activity http://purl.obolibrary.org/obo/GO_0008395 GO:0033336 biolink:BiologicalProcess caudal fin development The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0033336 CHEBI:138056 biolink:ChemicalSubstance 2,4,5-trihydroxyphenylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138056 chebi_ph7_3 GO:0033335 biolink:BiologicalProcess anal fin development The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0033335 CHEBI:138055 biolink:ChemicalSubstance 2,4,5-trihydroxyphenylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138055 GO:0033334 biolink:BiologicalProcess fin morphogenesis The process in which the anatomical structures of a fin are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0033334 CHEBI:138054 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_138054 CHEBI:138053 biolink:ChemicalSubstance 5-methoxycarbonylmethoxyuridine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138053 chebi_ph7_3 GO:0033333 biolink:BiologicalProcess fin development The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0033333 GO:0033332 biolink:BiologicalProcess ent-kaurene biosynthetic process The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins. MetaCyc:PWY-5035|MetaCyc:PWY-5032 go-plus.json ent-kaurene biosynthesis|ent-kaurene anabolism|ent-kaurene synthesis|ent-kaurene formation http://purl.obolibrary.org/obo/GO_0033332 GO:0033331 biolink:BiologicalProcess ent-kaurene metabolic process The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins. go-plus.json ent-kaurene metabolism http://purl.obolibrary.org/obo/GO_0033331 CHEBI:138059 biolink:ChemicalSubstance N-terminal L-prolyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138059 chebi_ph7_3 GO:0033330 biolink:BiologicalProcess kaempferol O-glucoside biosynthetic process The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol. MetaCyc:PWY-5320 go-plus.json kaempferol O-glucoside formation|kaempferol O-glucoside biosynthesis|kaempferol O-glucoside anabolism|kaempferol O-glucoside synthesit http://purl.obolibrary.org/obo/GO_0033330 CHEBI:138058 biolink:ChemicalSubstance N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138058 chebi_ph7_3 CHEBI:138057 biolink:ChemicalSubstance N-terminal L-alanyl-L-prolyl-L-lysyl(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138057 chebi_ph7_3 GO:0033329 biolink:BiologicalProcess kaempferol O-glucoside metabolic process The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol. go-plus.json kaempferol O-glucoside metabolism http://purl.obolibrary.org/obo/GO_0033329 GO:0033328 biolink:MolecularActivity peroxisome membrane targeting sequence binding Binding to a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane. go-plus.json mPTS binding|PMP targeting signal binding|peroxisomal membrane protein (PMP) targeting signal (mPTS) binding|PMP targeting signal (mPTS) binding http://purl.obolibrary.org/obo/GO_0033328 GO:0033327 biolink:BiologicalProcess Leydig cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. go-plus.json http://purl.obolibrary.org/obo/GO_0033327 GO:0033326 biolink:BiologicalProcess cerebrospinal fluid secretion The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces. go-plus.json CSF secretion http://purl.obolibrary.org/obo/GO_0033326 GO:0008369 biolink:MolecularActivity obsolete molecular function OBSOLETE. These are terms that have been removed from the active function ontology. go-plus.json http://purl.obolibrary.org/obo/GO_0008369 GO:0008368 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008368 GO:0008367 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008367 GO:0008366 biolink:BiologicalProcess axon ensheathment Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. go-plus.json cellular axon ensheathment|nerve ensheathment|cellular nerve ensheathment http://purl.obolibrary.org/obo/GO_0008366 GO:0008365 biolink:BiologicalProcess adult chitin-based cuticle development Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster. go-plus.json adult chitin-based cuticle synthesis|adult chitin-based cuticle formation|adult cuticle anabolism|adult cuticle synthesis|adult chitin-based cuticle biosynthetic process|adult cuticle formation|adult cuticle biosynthetic process|adult chitin-based cuticle anabolism http://purl.obolibrary.org/obo/GO_0008365 GO:0008364 biolink:BiologicalProcess pupal chitin-based cuticle development Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster. go-plus.json pupal cuticle anabolism|pupal cuticle synthesis|pupal cuticle formation http://purl.obolibrary.org/obo/GO_0008364 GO:0008363 biolink:BiologicalProcess larval chitin-based cuticle development Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster. go-plus.json larval cuticle biosynthetic process|larval cuticle anabolism|larval cuticle synthesis|larval cuticle formation http://purl.obolibrary.org/obo/GO_0008363 GO:0008362 biolink:BiologicalProcess chitin-based embryonic cuticle biosynthetic process Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster. go-plus.json embryonic cuticle anabolism|embryonic cuticle synthesis|embryonic cuticle formation|embryonic cuticle biosynthetic process http://purl.obolibrary.org/obo/GO_0008362 GO:0008372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008372 GO:0008371 biolink:BiologicalProcess obsolete biological process OBSOLETE. These are terms that have been removed from the active process ontology. go-plus.json http://purl.obolibrary.org/obo/GO_0008371 CHEBI:138029 biolink:ChemicalSubstance 14alpha-methyl steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138029 chebi_ph7_3 GO:0008370 biolink:CellularComponent obsolete cellular component OBSOLETE. These are terms that have been removed from the active component ontology. go-plus.json http://purl.obolibrary.org/obo/GO_0008370 GO:0033325 biolink:BiologicalProcess choline biosynthetic process via phosphoryl-ethanolamine The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine. MetaCyc:PWY-4762|MetaCyc:PWY-3385 go-plus.json choline anabolism via phosphoryl-ethanolamine|choline synthesis via phosphoryl-ethanolamine|choline formation via phosphoryl-ethanolamine|choline biosynthesis via phosphoryl-ethanolamine http://purl.obolibrary.org/obo/GO_0033325 GO:0033324 biolink:BiologicalProcess choline biosynthetic process via N-monomethylethanolamine The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine. MetaCyc:PWY-3542|MetaCyc:PWY-4762 go-plus.json choline biosynthesis via N-monomethylethanolamine|choline formation via N-monomethylethanolamine|choline synthesis via N-monomethylethanolamine|choline anabolism via N-monomethylethanolamine http://purl.obolibrary.org/obo/GO_0033324 GO:0033323 biolink:BiologicalProcess choline biosynthetic process via CDP-choline The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline. MetaCyc:PWY-4762|MetaCyc:PWY-3561 go-plus.json choline anabolism via CDP-choline|choline synthesis via CDP-choline|choline formation via CDP-choline|choline biosynthesis via CDP-choline http://purl.obolibrary.org/obo/GO_0033323 CHEBI:138021 biolink:ChemicalSubstance (3S)-3-hydroxy-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138021 chebi_ph7_3 GO:0033322 biolink:BiologicalProcess homomethionine biosynthetic process The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation. MetaCyc:PWY-1186 go-plus.json homomethionine anabolism|homomethionine synthesis|homomethionine biosynthesis|homomethionine formation http://purl.obolibrary.org/obo/GO_0033322 CHEBI:138020 biolink:ChemicalSubstance alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138020 GO:0033321 biolink:BiologicalProcess homomethionine metabolic process The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation. go-plus.json homomethionine metabolism http://purl.obolibrary.org/obo/GO_0033321 CHEBI:138027 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_138027 chebi_ph7_3 GO:0033320 biolink:BiologicalProcess UDP-D-xylose biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-4821 go-plus.json UDP-D-xylose anabolism|UDP-D-xylose biosynthesis|UDP-D-xylose synthesis|UDP-D-xylose formation http://purl.obolibrary.org/obo/GO_0033320 CHEBI:138026 biolink:ChemicalSubstance 5alpha-dihydrotestosterone sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138026 CHEBI:138025 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_138025 chebi_ph7_3 CHEBI:138024 biolink:ChemicalSubstance alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_138024 chebi_ph7_3 GO:0033319 biolink:BiologicalProcess UDP-D-xylose metabolic process The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate. go-plus.json UDP-D-xylose metabolism http://purl.obolibrary.org/obo/GO_0033319 GO:0033318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033318 CHEBI:138041 biolink:ChemicalSubstance (+)-4-epi-cubebol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138041 chebi_ph7_3 GO:0033317 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033317 CHEBI:138040 biolink:ChemicalSubstance 7-epi-alpha-eudesmol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138040 chebi_ph7_3 GO:0033316 biolink:BiologicalProcess meiotic spindle assembly checkpoint signaling A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle. go-plus.json signal transduction involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_0033316 GO:0033315 biolink:BiologicalProcess meiotic G2/MI DNA replication checkpoint signaling A signal transduction process that controls the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete. go-plus.json signal transduction involved in meiotic DNA replication checkpoint|meiotic G2/MI DNA replication checkpoint|meiotic cell cycle DNA replication checkpoint http://purl.obolibrary.org/obo/GO_0033315 GO:0047900 biolink:MolecularActivity formate kinase activity Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+). MetaCyc:FORMATE-KINASE-RXN|RHEA:16009|EC:2.7.2.6|KEGG_REACTION:R00518 go-plus.json ATP:formate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047900 GO:0008379 biolink:MolecularActivity thioredoxin peroxidase activity Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O. Reactome:R-HSA-3697894|RHEA:63528|Reactome:R-HSA-3322995|Reactome:R-HSA-3697882|MetaCyc:RXN0-267|Reactome:R-HSA-2161612|Reactome:R-HSA-3341343 go-plus.json TPx activity|thiol peroxidase activity|TrxPx activity http://purl.obolibrary.org/obo/GO_0008379 GO:0008378 biolink:MolecularActivity galactosyltransferase activity Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid. Reactome:R-HSA-1964501 go-plus.json http://purl.obolibrary.org/obo/GO_0008378 CHEBI:83547 biolink:ChemicalSubstance N(4)-aminopropylspermidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83547 GO:0008377 biolink:BiologicalProcess light-induced release of internally sequestered calcium ion The process in which the detection of light triggers the release of internally sequestered calcium ions. go-plus.json light-induced release of calcium from internal store|light-induced release of internally sequestered calcium ion (Ca2+)|light-induced release of internally stored calcium ion (Ca2+) http://purl.obolibrary.org/obo/GO_0008377 CHEBI:83546 biolink:ChemicalSubstance caldopentamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83546 GO:0008376 biolink:MolecularActivity acetylgalactosaminyltransferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide. Reactome:R-HSA-9605700|Reactome:R-HSA-8931648|Reactome:R-HSA-8855954 go-plus.json GalNAc transferase activity http://purl.obolibrary.org/obo/GO_0008376 CHEBI:83545 biolink:ChemicalSubstance agmatidine 5'-phosphate(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83545 chebi_ph7_3 GO:0008375 biolink:MolecularActivity acetylglucosaminyltransferase activity Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar. Reactome:R-HSA-9683648|Reactome:R-HSA-9694656|Reactome:R-HSA-5694487|Reactome:R-HSA-8879117 go-plus.json GlcNAc transferase activity http://purl.obolibrary.org/obo/GO_0008375 GO:0008374 biolink:MolecularActivity O-acyltransferase activity Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule. Reactome:R-HSA-1482781|Reactome:R-HSA-1482861|Reactome:R-HSA-5483229|Reactome:R-HSA-3238694|Reactome:R-HSA-162683|Reactome:R-HSA-422104|Reactome:R-HSA-422017|Reactome:R-HSA-1482867|Reactome:R-HSA-5358343|Reactome:R-HSA-1482775|Reactome:R-HSA-1482850 go-plus.json http://purl.obolibrary.org/obo/GO_0008374 GO:0008373 biolink:MolecularActivity sialyltransferase activity Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. Reactome:R-HSA-9697018|Reactome:R-HSA-9694718|Reactome:R-HSA-9683769|Reactome:R-HSA-981814 go-plus.json http://purl.obolibrary.org/obo/GO_0008373 GO:0047908 biolink:MolecularActivity fusarinine-C ornithinesterase activity Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol. MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN|RHEA:20165|EC:3.1.1.48 go-plus.json ornithine esterase activity|N5-acyl-L-ornithine-ester hydrolase activity|5-N-acyl-L-ornithine-ester hydrolase activity http://purl.obolibrary.org/obo/GO_0047908 GO:0008383 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008383 GO:0008382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008382 GO:0047907 biolink:MolecularActivity furylfuramide isomerase activity Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide. KEGG_REACTION:R04538|MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN|EC:5.2.1.6|RHEA:21848 go-plus.json 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity http://purl.obolibrary.org/obo/GO_0047907 GO:0008381 biolink:MolecularActivity mechanosensitive ion channel activity Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress. TC:1.A.23.2.1 go-plus.json mechanically-gated channel activity|mechanically-gated ion channel activity|mechanically gated channel activity http://purl.obolibrary.org/obo/GO_0008381 GO:0047906 biolink:MolecularActivity fucosterol-epoxide lyase activity Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol. EC:4.1.2.33|KEGG_REACTION:R03723|RHEA:10884|MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN go-plus.json (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity|(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming) http://purl.obolibrary.org/obo/GO_0047906 GO:0047905 biolink:MolecularActivity fructose-6-phosphate phosphoketolase activity Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. EC:4.1.2.22|RHEA:12196|MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN go-plus.json D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity http://purl.obolibrary.org/obo/GO_0047905 CHEBI:138039 biolink:ChemicalSubstance (3E,7E)-dolathalia-3,7,11-triene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138039 chebi_ph7_3 GO:0008380 biolink:BiologicalProcess RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. Wikipedia:RNA_splicing go-plus.json pre-mRNA splicing factor activity http://purl.obolibrary.org/obo/GO_0008380 goslim_yeast CHEBI:2700 biolink:ChemicalSubstance anandamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_2700 chebi_ph7_3 GO:0047904 biolink:MolecularActivity fructose 5-dehydrogenase activity Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2). RHEA:22304|KEGG_REACTION:R00873|MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN|EC:1.1.99.11 go-plus.json D-fructose:acceptor 5-oxidoreductase activity|fructose 5-dehydrogenase (acceptor)|D-fructose dehydrogenase activity|D-fructose:(acceptor) 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047904 GO:0047903 biolink:MolecularActivity fructose 5-dehydrogenase (NADP+) activity Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH. RHEA:14069|EC:1.1.1.124|MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN go-plus.json D-fructose:NADP+ 5-oxidoreductase activity|5-ketofructose reductase (NADP+) activity|5-ketofructose reductase (NADP(+)) activity|5-keto-D-fructose reductase (NADP+)|D-(-)fructose:(NADP+) 5-oxidoreductase activity|5-ketofructose reductase (NADP)|fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047903 GO:0047902 biolink:MolecularActivity formylaspartate deformylase activity Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate. MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN|EC:3.5.1.8|RHEA:22040 go-plus.json formylaspartic formylase (formylase I, formylase II)|N-formyl-L-aspartate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0047902 GO:0047901 biolink:MolecularActivity formyl-CoA hydrolase activity Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+). EC:3.1.2.10|KEGG_REACTION:R00521|RHEA:19741|MetaCyc:FORMYL-COA-HYDROLASE-RXN go-plus.json formyl coenzyme A hydrolase activity http://purl.obolibrary.org/obo/GO_0047901 GO:0033314 biolink:BiologicalProcess mitotic DNA replication checkpoint signaling A signal transduction process that contributes to a mitotic DNA replication checkpoint. go-plus.json signal transduction involved in mitotic G2/M transition decatenation checkpoint|signal transduction involved in S-M checkpoint|signal transduction involved in mitotic DNA replication checkpoint|S-phase checkpoint|S-M checkpoint|mitotic cell cycle DNA replication checkpoint|S-M DNA replication checkpoint|mitotic DNA replication checkpoint http://purl.obolibrary.org/obo/GO_0033314 CHEBI:138034 biolink:ChemicalSubstance dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138034 chebi_ph7_3 GO:0033313 biolink:BiologicalProcess meiotic cell cycle checkpoint signaling A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage. go-plus.json signal transduction involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint http://purl.obolibrary.org/obo/GO_0033313 GO:0033312 biolink:BiologicalProcess chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a. MetaCyc:PWY-5064 go-plus.json chlorophyll a formation via geranylgeranyl-chlorophyll a|chlorophyll a biosynthesis via geranylgeranyl-chlorophyll a|chlorophyll a synthesis via geranylgeranyl-chlorophyll a|chlorophyll a anabolism via geranylgeranyl-chlorophyll a http://purl.obolibrary.org/obo/GO_0033312 CHEBI:138032 biolink:ChemicalSubstance (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138032 GO:0033311 biolink:BiologicalProcess chlorophyll a biosynthetic process via phytyl diphosphate The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate. MetaCyc:PWY-5086 go-plus.json chlorophyll a biosynthetic process via phytyl-PP|chlorophyll a biosynthesis via phytyl diphosphate|chlorophyll a synthesis via phytyl diphosphate|chlorophyll a anabolism via phytyl diphosphate|chlorophyll a formation via phytyl chlorophyll a formation via phytyl-PP http://purl.obolibrary.org/obo/GO_0033311 CHEBI:138031 biolink:ChemicalSubstance Delta(14) steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138031 chebi_ph7_3 GO:0033310 biolink:BiologicalProcess chlorophyll a catabolic process The chemical reactions and pathways leading to the breakdown of chlorophyll a. MetaCyc:PWY-5098|MetaCyc:PWY-5086 go-plus.json chlorophyll a degradation|chlorophyll a breakdown|chlorophyll a catabolism http://purl.obolibrary.org/obo/GO_0033310 CHEBI:138037 biolink:ChemicalSubstance 10-epi-juneol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138037 chebi_ph7_3 GO:0047909 biolink:MolecularActivity galactolipid O-acyltransferase activity Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol. MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN|EC:2.3.1.134 go-plus.json mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity|galactolipid:galactolipid acyltransferase activity http://purl.obolibrary.org/obo/GO_0047909 CHEBI:138035 biolink:ChemicalSubstance S-mycothiol-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138035 chebi_ph7_3 GO:0033309 biolink:CellularComponent SBF transcription complex A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p. go-plus.json SBF complex http://purl.obolibrary.org/obo/GO_0033309 GO:0033308 biolink:BiologicalProcess hydroxyectoine transport The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0033308 GO:0033307 biolink:BiologicalProcess phytol salvage A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis. MetaCyc:PWY-5107 go-plus.json phytol salvage pathway http://purl.obolibrary.org/obo/GO_0033307 GO:0033306 biolink:BiologicalProcess phytol metabolic process The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol. go-plus.json phytol metabolism http://purl.obolibrary.org/obo/GO_0033306 GO:0008349 biolink:MolecularActivity MAP kinase kinase kinase kinase activity Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli. Reactome:R-HSA-177692|Reactome:R-HSA-9645442|Reactome:R-HSA-936991 go-plus.json MAP4K activity|MAPKKKK http://purl.obolibrary.org/obo/GO_0008349 GO:0033305 biolink:BiologicalProcess chlorophyll a biosynthetic process The chemical reactions and pathways leading to the formation of chlorophyll a. go-plus.json chlorophyll a anabolism|chlorophyll a synthesis|chlorophyll a biosynthesis|chlorophyll a formation http://purl.obolibrary.org/obo/GO_0033305 GO:0008348 biolink:BiologicalProcess negative regulation of antimicrobial humoral response Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response. go-plus.json attenuation of antimicrobial humoral response|down regulation of antimicrobial humoral response|inhibition of antimicrobial humoral response|down-regulation of antimicrobial humoral response|downregulation of antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0008348 GO:0033304 biolink:BiologicalProcess chlorophyll a metabolic process The chemical reactions and pathways involving chlorophyll a. go-plus.json chlorophyll a metabolism http://purl.obolibrary.org/obo/GO_0033304 GO:0008347 biolink:BiologicalProcess glial cell migration The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. go-plus.json glia cell migration http://purl.obolibrary.org/obo/GO_0008347 GO:0047911 biolink:MolecularActivity galacturan 1,4-alpha-galacturonidase activity Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate. EC:3.2.1.67|MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN|RHEA:14117 go-plus.json exopolygalacturonase activity|exo-D-galacturonanase activity|exo-polygalacturonase activity|exo-D-galacturonase activity|galacturan alpha-1,4-galacturonidase activity|poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity|exopoly-D-galacturonase activity|poly(galacturonate) hydrolase activity http://purl.obolibrary.org/obo/GO_0047911 GO:0047910 biolink:MolecularActivity galactose 1-dehydrogenase (NADP+) activity Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH. EC:1.1.1.120|MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN|RHEA:18625 go-plus.json D-galactose dehydrogenase (NADP+)|D-galactose:NADP+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047910 GO:0008346 biolink:BiologicalProcess larval walking behavior The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg. go-plus.json larval walking behaviour http://purl.obolibrary.org/obo/GO_0008346 GO:0008345 biolink:BiologicalProcess larval locomotory behavior Locomotory behavior in a larval (immature) organism. go-plus.json larval locomotory behaviour http://purl.obolibrary.org/obo/GO_0008345 GO:0008344 biolink:BiologicalProcess adult locomotory behavior Locomotory behavior in a fully developed and mature organism. go-plus.json adult locomotory behaviour http://purl.obolibrary.org/obo/GO_0008344 GO:0008343 biolink:BiologicalProcess adult feeding behavior Feeding behavior in a fully developed and mature organism. go-plus.json adult feeding behaviour http://purl.obolibrary.org/obo/GO_0008343 GO:0008342 biolink:BiologicalProcess obsolete larval feeding behavior (sensu Insecta) OBSOLETE. Feeding behavior in an insect larva. go-plus.json larval feeding behavior (sensu Insecta) http://purl.obolibrary.org/obo/GO_0008342 GO:0008341 biolink:BiologicalProcess obsolete response to cocaine (sensu Insecta) OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557). go-plus.json response to cocaine (sensu Insecta) http://purl.obolibrary.org/obo/GO_0008341 CHEBI:83554 biolink:ChemicalSubstance N(4)-aminopropylspermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83554 GO:0008340 biolink:BiologicalProcess determination of adult lifespan The control of viability and duration in the adult phase of the life-cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0008340 CHEBI:83553 biolink:ChemicalSubstance N(4)-bis(aminopropyl)spermidine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83553 GO:0047919 biolink:MolecularActivity GDP-mannose 6-dehydrogenase activity Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH. EC:1.1.1.132|RHEA:21728|MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN|KEGG_REACTION:R00880 go-plus.json GDP-D-mannose:NAD+ 6-oxidoreductase activity|guanosine diphospho-D-mannose dehydrogenase activity|guanosine diphosphomannose dehydrogenase activity|GDP mannose dehydrogenase activity|GDPmannose 6-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047919 GO:0008350 biolink:MolecularActivity obsolete kinetochore motor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json kinetochore motor activity http://purl.obolibrary.org/obo/GO_0008350 GO:0047918 biolink:MolecularActivity GDP-mannose 3,5-epimerase activity Catalysis of the reaction: GDP-mannose = GDP-L-galactose. MetaCyc:RXN-1882|EC:5.1.3.18|RHEA:11144 go-plus.json guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity|GDP-D-mannose:GDP-L-galactose epimerase activity|GDPmannose 3,5-epimerase activity http://purl.obolibrary.org/obo/GO_0047918 CHEBI:83550 biolink:ChemicalSubstance 1,2-ditetradecanoyl-sn-glycerol-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83550 chebi_ph7_3 CHEBI:138007 biolink:ChemicalSubstance N-acetyl-alpha-D-hexosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138007 chebi_ph7_3 GO:0047917 biolink:MolecularActivity GDP-glucosidase activity Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+). KEGG_REACTION:R00337|MetaCyc:GDP-GLUCOSIDASE-RXN|EC:3.2.1.42|RHEA:15049 go-plus.json GDPglucosidase activity|guanosine diphosphate D-glucose glucohydrolase activity|GDPglucose glucohydrolase activity|GDP-glucose glucohydrolase activity|guanosine diphosphoglucosidase activity http://purl.obolibrary.org/obo/GO_0047917 GO:0047916 biolink:MolecularActivity GDP-6-deoxy-D-talose 4-dehydrogenase activity Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+. EC:1.1.1.135|MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN go-plus.json guanosine diphospho-6-deoxy-D-talose dehydrogenase activity|GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047916 GO:0047915 biolink:MolecularActivity ganglioside galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine. EC:2.4.1.62|RHEA:16773|MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN go-plus.json uridine diphosphogalactose-GM2 galactosyltransferase activity|UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity|GM1-synthase activity|UDP-galactose-GM2 ganglioside galactosyltransferase activity|uridine diphosphate D-galactose:glycolipid galactosyltransferase activity|UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity|UDP-galactose-GM2 galactosyltransferase activity|uridine diphosphogalactose-ceramide galactosyltransferase activity|UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity|UDPgalactose-ceramide galactosyltransferase activity|UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047915 GO:0047914 biolink:MolecularActivity gamma-glutamylhistamine synthase activity Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown. EC:6.3.2.18|MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN|RHEA:18881 go-plus.json g-glutamylhistamine synthase activity|gamma-GHA synthetase activity|L-glutamate:histamine ligase activity|gamma-glutaminylhistamine synthetase activity http://purl.obolibrary.org/obo/GO_0047914 GO:0047913 biolink:MolecularActivity gallate 1-beta-glucosyltransferase activity Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP. MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:15249|KEGG_REACTION:R03297|EC:2.4.1.136 go-plus.json gallate 1-b-glucosyltransferase activity|UDP-glucose:gallate beta-D-glucosyltransferase activity|UDPglucose:vanillate 1-O-glucosyltransferase activity|UDP-glucose-vanillate 1-glucosyltransferase activity|UDPglucose:gallate glucosyltransferase activity|UDPglucose:gallate beta-D-glucosyltransferase activity|UDPglucose-vanillate 1-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047913 GO:0047912 biolink:MolecularActivity galacturonokinase activity Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+). MetaCyc:GALACTURONOKINASE-RXN|RHEA:12965|EC:2.7.1.44|KEGG_REACTION:R01980 go-plus.json ATP:D-galacturonate 1-phosphotransferase activity|galacturonokinase (phosphorylating) D-galacturonic acid kinase activity http://purl.obolibrary.org/obo/GO_0047912 GO:0033303 biolink:BiologicalProcess quercetin O-glucoside biosynthetic process The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin. MetaCyc:PWY-5321 go-plus.json quercetin O-glucoside anabolism|quercetin O-glucoside biosynthesis|quercetin O-glucoside synthesit|quercetin O-glucoside formation http://purl.obolibrary.org/obo/GO_0033303 GO:0033302 biolink:BiologicalProcess quercetin O-glucoside metabolic process The chemical reactions and pathways involving O-glucosylated derivatives of quercetin. go-plus.json quercetin O-glucoside metabolism http://purl.obolibrary.org/obo/GO_0033302 CHEBI:138000 biolink:ChemicalSubstance 3-(1-methylpyrrolidin-2-yl)pyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138000 GO:0033301 biolink:BiologicalProcess cell cycle comprising mitosis without cytokinesis A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N). go-plus.json http://purl.obolibrary.org/obo/GO_0033301 GO:0033300 biolink:MolecularActivity dehydroascorbic acid transmembrane transporter activity Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other. RHEA:60380|Reactome:R-HSA-198818 go-plus.json dehydroascorbic acid transporter activity|dehydroascorbate transporter activity http://purl.obolibrary.org/obo/GO_0033300 GO:0008359 biolink:BiologicalProcess regulation of bicoid mRNA localization Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location. go-plus.json regulation of bicoid mRNA localisation http://purl.obolibrary.org/obo/GO_0008359 GO:0008358 biolink:BiologicalProcess maternal determination of anterior/posterior axis, embryo The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos. go-plus.json http://purl.obolibrary.org/obo/GO_0008358 GO:0047922 biolink:MolecularActivity gentisate 1,2-dioxygenase activity Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+). RHEA:18237|EC:1.13.11.4|MetaCyc:GENTISATE-12-DIOXYGENASE-RXN|KEGG_REACTION:R02656 go-plus.json gentisate oxygenase activity|2,5-dihydroxybenzoate dioxygenase activity|gentisate:oxygen 1,2-oxidoreductase (decyclizing)|gentisic acid oxidase activity|gentisate dioxygenase activity http://purl.obolibrary.org/obo/GO_0047922 GO:0047921 biolink:MolecularActivity aminoglycoside 2'-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring. KEGG_REACTION:R03056|MetaCyc:GENTAMICIN-2-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.59|RHEA:24516 go-plus.json gentamycin 2'-N-acetyltransferase activity|acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity|gentamicin acetyltransferase II activity|gentamicin 2'-N-acetyltransferase activity|gentamycin acetyltransferase II|acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047921 GO:0008357 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008357 GO:0008356 biolink:BiologicalProcess asymmetric cell division The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. Wikipedia:Asymmetric_cell_division go-plus.json asymmetrical cytokinesis|asymmetrical cell division|asymmetric cytokinesis http://purl.obolibrary.org/obo/GO_0008356 GO:0047920 biolink:MolecularActivity geissoschizine dehydrogenase activity Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH. RHEA:11376|KEGG_REACTION:R03860|EC:1.3.1.36|MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN go-plus.json geissoschizine:NADP+ 4,21-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047920 GO:0008355 biolink:BiologicalProcess olfactory learning Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. go-plus.json http://purl.obolibrary.org/obo/GO_0008355 GO:0008354 biolink:BiologicalProcess germ cell migration The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. go-plus.json primordial germ cell migration|germ-cell migration http://purl.obolibrary.org/obo/GO_0008354 GO:0008353 biolink:MolecularActivity RNA polymerase II CTD heptapeptide repeat kinase activity Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats. Reactome:R-HSA-170706|MetaCyc:RNA-POLYMERASE-SUBUNIT-KINASE-RXN|RHEA:10216|Reactome:R-HSA-167191|EC:2.7.11.23|Reactome:R-HSA-170704 go-plus.json STK9|RNA-polymerase-subunit kinase activity|RNA polymerase subunit kinase activity|ATP:DNA-directed RNA polymerase phosphotransferase activity|[RNA-polymerase]-subunit kinase activity|CTD kinase activity|RNA polymerase II carboxy-terminal domain kinase activity http://purl.obolibrary.org/obo/GO_0008353 NCBITaxon:116557 biolink:OrganismalEntity Phyllopoda go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_116557 GO:0008352 biolink:CellularComponent katanin complex A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa). go-plus.json http://purl.obolibrary.org/obo/GO_0008352 CHEBI:83565 biolink:ChemicalSubstance (trifluoromethyl)benzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_83565 CHEBI:83564 biolink:ChemicalSubstance (R)-3-phosphomevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83564 GO:0008351 biolink:MolecularActivity obsolete microtubule severing activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json microtubule severing activity http://purl.obolibrary.org/obo/GO_0008351 GO:0008361 biolink:BiologicalProcess regulation of cell size Any process that modulates the size of a cell. go-plus.json cell size control http://purl.obolibrary.org/obo/GO_0008361 CHEBI:83563 biolink:ChemicalSubstance long-chain alkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_83563 chebi_ph7_3 GO:0047929 biolink:MolecularActivity gluconate dehydratase activity Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O. RHEA:21612|MetaCyc:GLUCONATE-DEHYDRATASE-RXN|EC:4.2.1.39|KEGG_REACTION:R01538 go-plus.json D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)|D-gluconate dehydratase activity|D-gluconate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0047929 CHEBI:138019 biolink:ChemicalSubstance N(6)-propanoyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138019 chebi_ph7_3 CHEBI:83562 biolink:ChemicalSubstance N-terminal L-arginyl-L-alpha-amino acid(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83562 chebi_ph7_3 GO:0008360 biolink:BiologicalProcess regulation of cell shape Any process that modulates the surface configuration of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0008360 GO:0047928 biolink:MolecularActivity gibberellin beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside. RHEA:20025|EC:2.4.1.176|MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN go-plus.json UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity|gibberellin b-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity|UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047928 CHEBI:83561 biolink:ChemicalSubstance N-terminal L-phenylalanyl-L-alpha-amino acid(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83561 chebi_ph7_3 GO:0047927 biolink:MolecularActivity gibberellin-44 dioxygenase activity Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2. RHEA:16033|EC:1.14.11.12|MetaCyc:RXN1F-168 go-plus.json (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity|oxygenase, gibberellin A44 oxidase activity|(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity|gibberellin A44 oxidase activity http://purl.obolibrary.org/obo/GO_0047927 GO:0047926 biolink:MolecularActivity geranyl-diphosphate cyclase activity Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate. KEGG_REACTION:R02007|EC:5.5.1.8|RHEA:18209|MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN go-plus.json bornyl diphosphate synthase activity|bornyl pyrophosphate synthase activity|(+)-bornylpyrophosphate cyclase activity|bornyl pyrophosphate synthetase activity|(+)-bornyl-diphosphate lyase (decyclizing) http://purl.obolibrary.org/obo/GO_0047926 NCBITaxon:116561 biolink:OrganismalEntity Anomopoda go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_116561 GO:0047925 biolink:MolecularActivity geranoyl-CoA carboxylase activity Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate. UM-BBD_reactionID:r1166|RHEA:17701|EC:6.4.1.5|KEGG_REACTION:R03494|MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN go-plus.json geranyl-CoA carboxylase activity|geranoyl coenzyme A carboxylase activity|geranoyl-CoA:carbon-dioxide ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0047925 GO:0047924 biolink:MolecularActivity geraniol dehydrogenase activity Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH. RHEA:14521|UM-BBD_reactionID:r1163|EC:1.1.1.183|MetaCyc:GERANIOL-DEHYDROGENASE-RXN go-plus.json geraniol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047924 GO:0047923 biolink:MolecularActivity gentisate decarboxylase activity Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone. KEGG_REACTION:R02489|RHEA:21312|EC:4.1.1.62|MetaCyc:GENTISATE-DECARBOXYLASE-RXN go-plus.json 2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)|2,5-dihydroxybenzoate decarboxylase activity|gentisate carboxy-lyase activity http://purl.obolibrary.org/obo/GO_0047923 CHEBI:138011 biolink:ChemicalSubstance 6-(alpha-D-glucose-1-phospho)-alpha-D-mannoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138011 chebi_ph7_3 CHEBI:138015 biolink:ChemicalSubstance endocrine disruptor go-plus.json http://purl.obolibrary.org/obo/CHEBI_138015 CHEBI:10502 biolink:ChemicalSubstance dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_10502 CHEBI:2716 biolink:ChemicalSubstance anethole go-plus.json http://purl.obolibrary.org/obo/CHEBI_2716 chebi_ph7_3 CHEBI:2719 biolink:ChemicalSubstance Ile(5)-angiotensin II go-plus.json http://purl.obolibrary.org/obo/CHEBI_2719 CHEBI:2710 biolink:ChemicalSubstance androst-5-ene-3beta,17beta-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_2710 chebi_ph7_3 CHEBI:10525 biolink:ChemicalSubstance dTDP-beta-L-mycarose go-plus.json http://purl.obolibrary.org/obo/CHEBI_10525 GO:0033295 biolink:MolecularActivity hydroxyectoine binding Binding to hydroxyectoine. go-plus.json http://purl.obolibrary.org/obo/GO_0033295 GO:0033294 biolink:MolecularActivity ectoine binding Binding to ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0033294 GO:0033293 biolink:MolecularActivity monocarboxylic acid binding Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). go-plus.json http://purl.obolibrary.org/obo/GO_0033293 GO:0033292 biolink:BiologicalProcess T-tubule organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. go-plus.json T-tubule organization and biogenesis|T-tubule organisation|transverse tubule organization http://purl.obolibrary.org/obo/GO_0033292 GO:0033291 biolink:CellularComponent eukaryotic 80S initiation complex A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region. go-plus.json http://purl.obolibrary.org/obo/GO_0033291 GO:0033290 biolink:CellularComponent eukaryotic 48S preinitiation complex A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA. go-plus.json eukaryotic 48S pre-initiation complex|eukaryotic 48S initiation complex http://purl.obolibrary.org/obo/GO_0033290 GO:0033299 biolink:BiologicalProcess secretion of lysosomal enzymes The controlled release of lysosomal enzymes by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0033299 GO:0033298 biolink:BiologicalProcess contractile vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. go-plus.json contractile vacuole organisation|contractile vacuole organization and biogenesis http://purl.obolibrary.org/obo/GO_0033298 GO:0033297 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033297 GO:0033296 biolink:MolecularActivity rhamnose binding Binding to the D- or L-enantiomer of rhamnose. go-plus.json http://purl.obolibrary.org/obo/GO_0033296 GO:0033284 biolink:MolecularActivity ATPase-coupled carboxylic acid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out). go-plus.json ATP-dependent carboxylic acid transporter activity|carboxylic acid-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0033284 GO:0033283 biolink:MolecularActivity ATPase-coupled organic acid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out). go-plus.json organic acid-transporting ATPase activity|ATP-dependent organic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0033283 GO:0033282 biolink:CellularComponent protein C inhibitor-acrosin complex A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin. go-plus.json plasma serine protease inhibitor-acrosin complex|serpin A5-acrosin complex|PCI-acrosin complex|PCI-ACR complex|SERPINA5-acrosin complex http://purl.obolibrary.org/obo/GO_0033282 GO:0033281 biolink:CellularComponent TAT protein transport complex A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins. go-plus.json TAT protein translocation system complex|Twin-arginine translocation complex|TAT protein secretion complex http://purl.obolibrary.org/obo/GO_0033281 GO:0033280 biolink:BiologicalProcess response to vitamin D Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus. go-plus.json response to calciferol|response to cholecalciferol|response to ergocalciferol http://purl.obolibrary.org/obo/GO_0033280 GO:0033289 biolink:CellularComponent intraconoid microtubule A microtubule located such that it threads through the conoid and projects through the polar ring. go-plus.json http://purl.obolibrary.org/obo/GO_0033289 GO:0033288 biolink:MolecularActivity ATPase-coupled hydroxyectoine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out). go-plus.json ATP-dependent hydroxyectoine transmembrane transporter activity|hydroxyectoine-transporting ATPase activity|hydroxyectoine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0033288 GO:0033287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033287 GO:0033286 biolink:MolecularActivity ATPase-coupled ectoine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out). RHEA:32787 go-plus.json ectoine-transporting ATPase activity|ectoine transmembrane transporter activity|ATP-dependent ectoine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0033286 GO:0033285 biolink:MolecularActivity ATPase-coupled monocarboxylic acid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out). go-plus.json ATP-dependent monocarboxylic acid transmembrane transporter activity|monocarboxylic acid-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0033285 UBERON:3010200 biolink:AnatomicalEntity vasculature of respiratory integument Blood vessels in respiratory skin. go-plus.json http://purl.obolibrary.org/obo/UBERON_3010200 GO:0033273 biolink:BiologicalProcess response to vitamin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0033273 GO:0033272 biolink:BiologicalProcess myo-inositol hexakisphosphate transport The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json phytate transport http://purl.obolibrary.org/obo/GO_0033272 GO:0033271 biolink:BiologicalProcess myo-inositol phosphate transport The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0033271 GO:0033270 biolink:CellularComponent paranode region of axon An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath. NIF_Subcellular:sao234066064|NIF_Subcellular:sao936144858 go-plus.json paranode http://purl.obolibrary.org/obo/GO_0033270 GO:0033279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033279 GO:0033278 biolink:BiologicalProcess cell proliferation in midbrain The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. go-plus.json cell proliferation in mesencephalon|mesencepahalic cell proliferation http://purl.obolibrary.org/obo/GO_0033278 GO:0033277 biolink:BiologicalProcess abortive mitotic cell cycle A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy. go-plus.json abortive mitosis http://purl.obolibrary.org/obo/GO_0033277 GO:0033276 biolink:CellularComponent transcription factor TFTC complex A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0033276 GO:0033275 biolink:BiologicalProcess actin-myosin filament sliding The sliding movement of actin thin filaments and myosin thick filaments past each other. go-plus.json actin filament sliding http://purl.obolibrary.org/obo/GO_0033275 GO:0033274 biolink:BiologicalProcess response to vitamin B2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus. go-plus.json response to riboflavin http://purl.obolibrary.org/obo/GO_0033274 CHEBI:138092 biolink:ChemicalSubstance 1-[(Z)-alk-1-enyl]-sn-glycero-3-phospho-(N-acyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138092 CHEBI:138096 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-arachidonoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138096 CHEBI:138095 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-oleoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138095 CHEBI:138094 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-hexadecanoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138094 CHEBI:138093 biolink:ChemicalSubstance N-acyl-aromatic L-alpha-amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138093 chebi_ph7_3 GO:0033262 biolink:BiologicalProcess regulation of nuclear cell cycle DNA replication Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. go-plus.json regulation of DNA replication involved in S-phase|regulation of DNA replication during S phase|regulation of DNA replication involved in S phase http://purl.obolibrary.org/obo/GO_0033262 GO:0033261 biolink:BiologicalProcess obsolete regulation of S phase OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle. MetaCyc:SALVADEHYPOX-PWY|MetaCyc:PWY-5043|MetaCyc:SALVPURINE2-PWY go-plus.json regulation of S phase|regulation of S-phase|regulation of progression through S phase http://purl.obolibrary.org/obo/GO_0033261 GO:0033260 biolink:BiologicalProcess nuclear DNA replication The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. go-plus.json DNA replication during S phase|DNA replication involved in S phase|nuclear cell cycle DNA replication|DNA replication involved in S-phase http://purl.obolibrary.org/obo/GO_0033260 CHEBI:138088 biolink:ChemicalSubstance long chain primary alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138088 chebi_ph7_3 GO:0033269 biolink:CellularComponent internode region of axon An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath. NIF_Subcellular:sao206157942 go-plus.json internode http://purl.obolibrary.org/obo/GO_0033269 GO:0033268 biolink:CellularComponent node of Ranvier An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed. NIF_Subcellular:birnlex_1152_2|Wikipedia:Nodes_of_Ranvier go-plus.json node of Ranvier axon http://purl.obolibrary.org/obo/GO_0033268 CHEBI:138087 biolink:ChemicalSubstance O-acyl-ADP-D-ribose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138087 chebi_ph7_3 GO:0033267 biolink:CellularComponent obsolete axon part OBSOLETE. A part of an axon, a cell projection of a neuron. NIF_Subcellular:sao280355188 go-plus.json http://purl.obolibrary.org/obo/GO_0033267 gocheck_do_not_annotate GO:0033266 biolink:MolecularActivity ABC-type choline transporter activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane. go-plus.json choline-transporting ATPase activity|ABC-type choline transmembrane transporter activity|ATPase-coupled choline transmembrane transporter activity|ATP-dependent choline transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0033266 GO:0033265 biolink:MolecularActivity choline binding Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium. go-plus.json http://purl.obolibrary.org/obo/GO_0033265 GO:0033264 biolink:MolecularActivity obsolete bontoxilysin activity OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates. go-plus.json bontoxilysin activity|BoNT|botulinum neurotoxin activity http://purl.obolibrary.org/obo/GO_0033264 GO:0033263 biolink:CellularComponent CORVET complex A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p. go-plus.json http://purl.obolibrary.org/obo/GO_0033263 GO:0033251 biolink:MolecularActivity cephalosporinase activity Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. MetaCyc:BETA-LACTAMASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0033251 CHEBI:2762 biolink:ChemicalSubstance antimycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_2762 chebi_ph7_3 GO:0033250 biolink:MolecularActivity penicillinase activity Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin. MetaCyc:BETA-LACTAMASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0033250 GO:0033259 biolink:BiologicalProcess plastid DNA replication The process in which new strands of DNA are synthesized in a plastid. go-plus.json plastid DNA synthesis|replication of plastid DNA http://purl.obolibrary.org/obo/GO_0033259 GO:0033258 biolink:BiologicalProcess plastid DNA metabolic process The chemical reactions and pathways involving plastid DNA. go-plus.json plastid DNA metabolism http://purl.obolibrary.org/obo/GO_0033258 CHEBI:138099 biolink:ChemicalSubstance 2-[(9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138099 chebi_ph7_3 NCBITaxon:297308 biolink:OrganismalEntity Ixodoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_297308 CHEBI:138098 biolink:ChemicalSubstance 2-[(9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138098 chebi_ph7_3 GO:0033257 biolink:CellularComponent Bcl3/NF-kappaB2 complex A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription. go-plus.json Bcl3-NFKB2 complex|Bcl3-p52 complex http://purl.obolibrary.org/obo/GO_0033257 GO:0033256 biolink:CellularComponent I-kappaB/NF-kappaB complex A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0033256 goslim_pir CHEBI:138097 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_138097 GO:0033255 biolink:CellularComponent SAS acetyltransferase complex A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p. go-plus.json SAS-I complex http://purl.obolibrary.org/obo/GO_0033255 GO:0033254 biolink:CellularComponent vacuolar transporter chaperone complex A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p. go-plus.json VTC complex http://purl.obolibrary.org/obo/GO_0033254 GO:0033253 biolink:BiologicalProcess regulation of penicillinase activity Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0033253 GO:0033252 biolink:BiologicalProcess regulation of beta-lactamase activity Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0033252 GO:0047892 biolink:MolecularActivity flavone apiosyltransferase activity Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone. EC:2.4.2.25|MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN|RHEA:19153 go-plus.json UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity|uridine diphosphoapiose-flavone apiosyltransferase activity|UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity http://purl.obolibrary.org/obo/GO_0047892 GO:0047891 biolink:MolecularActivity flavone 7-O-beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone. EC:2.4.1.81|RHEA:19577|MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN go-plus.json UDP-glucose-apigenin beta-glucosyltransferase activity|UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-luteolin beta-D-glucosyltransferase activity|uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity|UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-apigenin beta-glucosyltransferase activity|flavone 7-O-b-glucosyltransferase activity|UDP-glucose-luteolin beta-D-glucosyltransferase activity|uridine diphosphoglucose-luteolin glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047891 GO:0047890 biolink:MolecularActivity flavanone 4-reductase activity Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH. RHEA:11228|EC:1.1.1.234|MetaCyc:FLAVANONE-4-REDUCTASE-RXN go-plus.json (2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity|flavonone 4-reductase activity http://purl.obolibrary.org/obo/GO_0047890 CHEBI:58539 biolink:ChemicalSubstance L-dehydroascorbate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58539 chebi_ph7_3 GO:0047899 biolink:MolecularActivity formate dehydrogenase (NADP+) activity Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH. MetaCyc:FORMATE-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R00134|EC:1.17.1.10|RHEA:12000 go-plus.json NADP-dependent formate dehydrogenase activity|formate:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047899 GO:0047898 biolink:MolecularActivity formate dehydrogenase (cytochrome) activity Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1. MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:21520|EC:1.2.2.1 go-plus.json formate:ferricytochrome-b1 oxidoreductase activity|formate:cytochrome b1 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047898 GO:0047897 biolink:MolecularActivity formate-dihydrofolate ligase activity Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate. MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN|RHEA:24328|EC:6.3.4.17|KEGG_REACTION:R02238 go-plus.json formate:dihydrofolate ligase (ADP-forming)|formyl dihydrofolate synthase activity|dihydrofolate formyltransferase activity http://purl.obolibrary.org/obo/GO_0047897 GO:0047896 biolink:MolecularActivity formaldehyde transketolase activity Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone. MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN|RHEA:24264|EC:2.2.1.3 go-plus.json glycerone synthase activity|dihydroxyacetone synthase activity|DHAS activity|D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity http://purl.obolibrary.org/obo/GO_0047896 GO:0047895 biolink:MolecularActivity formaldehyde dismutase activity Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate. MetaCyc:FORMALDEHYDE-DISMUTASE-RXN|EC:1.2.98.1|RHEA:19221 go-plus.json aldehyde dismutase activity|formaldehyde:formaldehyde oxidoreductase activity|cannizzanase activity|nicotinoprotein aldehyde dismutase http://purl.obolibrary.org/obo/GO_0047895 GO:0047894 biolink:MolecularActivity flavonol 3-sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate. MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN|EC:2.8.2.25|KEGG_REACTION:R02159|RHEA:13453 go-plus.json flavonol 3-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047894 goslim_chembl GO:0047893 biolink:MolecularActivity flavonol 3-O-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside. RHEA:22300|EC:2.4.1.91|MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN go-plus.json uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity|UDP-glucose flavonol 3-O-glucosyltransferase activity|UDPglucose:flavonol 3-O-D-glucosyltransferase activity|UDP-glucose:flavonol 3-O-D-glucosyltransferase activity|GTI|UDPG:flavonoid-3-O-glucosyltransferase activity|UDP-glucose:flavonol 3-O-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047893 CHEBI:58530 biolink:ChemicalSubstance gentamycin C1a(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58530 chebi_ph7_3 CHEBI:58538 biolink:ChemicalSubstance (R)-3-hydroxy-2-oxo-4-(phosphonatoooxy)butanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58538 chebi_ph7_3 CHEBI:58537 biolink:ChemicalSubstance cob(II)yrinic acid a,c diamide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58537 chebi_ph7_3 CHEBI:58536 biolink:ChemicalSubstance hydrogenobyrinic acid a,c-diamide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58536 CHEBI:58535 biolink:ChemicalSubstance N(8)-acetylspermidinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58535 chebi_ph7_3 CHEBI:58534 biolink:ChemicalSubstance 6-phospho-beta-D-galactoside(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58534 chebi_ph7_3 CHEBI:58533 biolink:ChemicalSubstance S-methyl-5-thio-alpha-D-ribose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58533 chebi_ph7_3 CHEBI:58532 biolink:ChemicalSubstance precorrin-6Y(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58532 chebi_ph7_3 CHEBI:58531 biolink:ChemicalSubstance Se-methyl-L-selenocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58531 chebi_ph7_3 CHEBI:58529 biolink:ChemicalSubstance P(1),P(3)-bis(5'-adenosyl) triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58529 chebi_ph7_3 CHEBI:58528 biolink:ChemicalSubstance 3-hydroxypropanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58528 chebi_ph7_3 UBERON:2001314 biolink:AnatomicalEntity posterior lateral line ganglion The posterior lateral line ganglion develops from a cranial ectodermal placode and contains sensory neurons that innervate the posterior lateral line system. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001314 UBERON:2001316 biolink:AnatomicalEntity anterior lateral line placode Dorsolateral placode that gives rise to the anterior lateral line. go-plus.json pre-auditory lateral line placode|anterior lateral line placodes http://purl.obolibrary.org/obo/UBERON_2001316 CHEBI:58527 biolink:ChemicalSubstance D-ribosylnicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58527 chebi_ph7_3 CHEBI:58526 biolink:ChemicalSubstance gibberellin A20(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58526 chebi_ph7_3 CHEBI:58525 biolink:ChemicalSubstance 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58525 chebi_ph7_3 CHEBI:58524 biolink:ChemicalSubstance gibberellin A1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58524 chebi_ph7_3 CHEBI:58523 biolink:ChemicalSubstance (5S)-5-amino-3-oxohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58523 chebi_ph7_3 CHEBI:58522 biolink:ChemicalSubstance precorrin-3B(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58522 CHEBI:58521 biolink:ChemicalSubstance trans-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58521 chebi_ph7_3 CHEBI:58520 biolink:ChemicalSubstance N-succinyl-L-glutamic 5-semialdehyde(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58520 chebi_ph7_3 CHEBI:58519 biolink:ChemicalSubstance (E)-2-benzylidenesuccinyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58519 chebi_ph7_3 CHEBI:58518 biolink:ChemicalSubstance precorrin-5(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58518 CHEBI:58517 biolink:ChemicalSubstance 3,4-dehydrothiomorpholine-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58517 chebi_ph7_3 CHEBI:58516 biolink:ChemicalSubstance alpha-D-glucosamine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58516 chebi_ph7_3 CHEBI:58515 biolink:ChemicalSubstance ectoine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58515 chebi_ph7_3 CHEBI:58514 biolink:ChemicalSubstance N(2)-succinyl-L-ornithinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58514 chebi_ph7_3 CHEBI:58513 biolink:ChemicalSubstance precorrin-6X(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58513 CHEBI:58511 biolink:ChemicalSubstance D-erythro-3-methylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58511 chebi_ph7_3 CHEBI:58510 biolink:ChemicalSubstance UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58510 chebi_ph7_3 CHEBI:58509 biolink:ChemicalSubstance 1-pyrroline-3-hydroxy-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58509 chebi_ph7_3 CHEBI:58507 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58507 chebi_ph7_3 CHEBI:58506 biolink:ChemicalSubstance Ile(5)-angiotensin II dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58506 chebi_ph7_3 OBO:GOCHE_50113 biolink:OntologyClass substance with androgen role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50113 3_STAR OBO:GOCHE_50112 biolink:OntologyClass substance with sex hormone role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50112 3_STAR OBO:GOCHE_50114 biolink:OntologyClass substance with estrogen role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50114 3_STAR CHEBI:58505 biolink:ChemicalSubstance mugineate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58505 NCBITaxon:189518 biolink:OrganismalEntity Leptospira interrogans serovar Lai str. 56601 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_189518 CHEBI:58504 biolink:ChemicalSubstance adenosylcobyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58504 chebi_ph7_3 CHEBI:58503 biolink:ChemicalSubstance adenosylcob(III)yrinate a,c-diamide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58503 chebi_ph7_3 CHEBI:58502 biolink:ChemicalSubstance adenosylcobinamide phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58502 chebi_ph7_3 CHEBI:58501 biolink:ChemicalSubstance 7beta-aminocephalosporanic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58501 chebi_ph7_3 CHEBI:58500 biolink:ChemicalSubstance 7,8-diaminononanoate cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_58500 chebi_ph7_3 UBERON:0015593 biolink:AnatomicalEntity frontal gyrus A gyrus that is part of a frontal cortex. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015593 CHEBI:34528 biolink:ChemicalSubstance adipoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_34528 CHEBI:10545 biolink:ChemicalSubstance electron go-plus.json http://purl.obolibrary.org/obo/CHEBI_10545 chebi_ph7_3 UBERON:2001391 biolink:AnatomicalEntity anterior lateral line ganglion The anteror lateral line ganglia develops from cranial ectodermal placodes and contain sensory neurons that innervate the anterior lateral line system. go-plus.json anterior lateral line ganglia http://purl.obolibrary.org/obo/UBERON_2001391 NCBITaxon:69541 biolink:OrganismalEntity Desulfuromonadales go-plus.json Desulfuromonas group|Desulfuromonales http://purl.obolibrary.org/obo/NCBITaxon_69541 CHEBI:10577 biolink:ChemicalSubstance gamma-terpinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10577 chebi_ph7_3 CHEBI:10576 biolink:ChemicalSubstance (3R,4S,5S,6R)-1,3,4,5,6-pentachlorocyclohexene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10576 chebi_ph7_3 UBERON:2001389 biolink:AnatomicalEntity regeneration epithelium of fin/limb A epithelium that is part of a regenerating fin/limb. go-plus.json wound epithelium of fin|epidermal cap|wound epidermis|wound epidermis of fin|epidermal cap of fin|wound epithelium http://purl.obolibrary.org/obo/UBERON_2001389 UBERON:2001388 biolink:AnatomicalEntity epithelial mesenchymal boundary of regenerating fin/limb A epithelial-mesenchymal boundary that is part of a regenerating fin/limb. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001388 GO:0033409 biolink:MolecularActivity UAU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UAU codon. go-plus.json TAT codon-amino acid adaptor activity|tyrosine tRNA http://purl.obolibrary.org/obo/GO_0033409 GO:0033408 biolink:MolecularActivity UCG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UCG codon. go-plus.json TCG codon-amino acid adaptor activity|serine tRNA http://purl.obolibrary.org/obo/GO_0033408 GO:0033407 biolink:MolecularActivity UCA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UCA codon. go-plus.json serine tRNA|TCA codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033407 GO:0033406 biolink:MolecularActivity UCC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UCC codon. go-plus.json TCC codon-amino acid adaptor activity|serine tRNA http://purl.obolibrary.org/obo/GO_0033406 GO:0008449 biolink:MolecularActivity N-acetylglucosamine-6-sulfatase activity Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate. MetaCyc:3.1.6.14-RXN|Reactome:R-HSA-1638032|Reactome:R-HSA-2263495|EC:3.1.6.14 go-plus.json N-acetylglucosamine-6-sulphatase activity|acetylglucosamine 6-sulfatase activity|O,N-disulfate O-sulfohydrolase activity|glucosamine-6-sulfatase activity|N-acetylglucosamine 6-sulfate sulfatase activity|2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity|chondroitinsulfatase|N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity http://purl.obolibrary.org/obo/GO_0008449 GO:0033405 biolink:MolecularActivity UCU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UCU codon. go-plus.json TCT codon-amino acid adaptor activity|serine tRNA http://purl.obolibrary.org/obo/GO_0033405 GO:0008448 biolink:MolecularActivity N-acetylglucosamine-6-phosphate deacetylase activity Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate. Reactome:R-HSA-6803789|RHEA:22936|EC:3.5.1.25|MetaCyc:NAG6PDEACET-RXN go-plus.json acetylglucosamine phosphate deacetylase activity|N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity|acetylaminodeoxyglucosephosphate acetylhydrolase activity|2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity http://purl.obolibrary.org/obo/GO_0008448 GO:0033404 biolink:MolecularActivity UUG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UUG codon. go-plus.json TTG codon-amino acid adaptor activity|leucine tRNA http://purl.obolibrary.org/obo/GO_0033404 GO:0008447 biolink:MolecularActivity L-ascorbate oxidase activity Catalysis of the reaction: 4 L-ascorbate + O(2) <=> 4 monodehydroascorbate + 2 H(2)O. EC:1.10.3.3|MetaCyc:L-ASCORBATE-OXIDASE-RXN|RHEA:30243 go-plus.json ascorbate oxidase activity|ascorbate dehydrogenase activity|ascorbic oxidase activity|L-ascorbate:O2 oxidoreductase activity|L-ascorbate:oxygen oxidoreductase activity|AAO|L-ascorbic acid oxidase activity|ascorbic acid oxidase activity|ascorbase activity|AA oxidase activity http://purl.obolibrary.org/obo/GO_0008447 GO:0033403 biolink:MolecularActivity UUA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UUA codon. go-plus.json TTA codon-amino acid adaptor activity|leucine tRNA http://purl.obolibrary.org/obo/GO_0033403 GO:0008446 biolink:MolecularActivity GDP-mannose 4,6-dehydratase activity Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O. MetaCyc:GDPMANDEHYDRA-RXN|Reactome:R-HSA-6787632|KEGG_REACTION:R00888|EC:4.2.1.47|RHEA:23820 go-plus.json guanosine diphosphomannose 4,6-dehydratase activity|GDP-D-mannose dehydratase activity|GDPmannose 4,6-dehydratase activity|GDP-mannose 4,6-hydro-lyase activity|Gmd|GDP-D-mannose 4,6-dehydratase activity|guanosine diphosphomannose oxidoreductase activity|guanosine 5'-diphosphate-D-mannose oxidoreductase activity|GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming) http://purl.obolibrary.org/obo/GO_0008446 GO:0008445 biolink:MolecularActivity D-aspartate oxidase activity Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide. EC:1.4.3.1|Reactome:R-HSA-6810076|MetaCyc:D-ASPARTATE-OXIDASE-RXN|RHEA:12512 go-plus.json D-aspartic oxidase activity|D-aspartate:oxygen oxidoreductase (deaminating)|aspartic oxidase activity http://purl.obolibrary.org/obo/GO_0008445 GO:0008444 biolink:MolecularActivity CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+). KEGG_REACTION:R01801|EC:2.7.8.5|MetaCyc:PHOSPHAGLYPSYN-RXN|Reactome:R-HSA-1482939|RHEA:12593 go-plus.json phosphatidylglycerolphosphate synthase activity|phosphatidylglycerophosphate synthetase activity|glycerol phosphate phosphatidyltransferase activity|phosphatidylglycerol phosphate synthase activity|CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|glycerol 3-phosphate phosphatidyltransferase activity|CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity|sn-glycerol-3-phosphate phosphatidyltransferase activity|3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity|phosphatidylglycerophosphate synthase activity|CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity|phosphatidylglycerol phosphate synthetase activity|glycerophosphate phosphatidyltransferase activity|PGP synthase activity|CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity http://purl.obolibrary.org/obo/GO_0008444 GO:0008443 biolink:MolecularActivity phosphofructokinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0008443 GO:0008442 biolink:MolecularActivity 3-hydroxyisobutyrate dehydrogenase activity Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+. RHEA:17681|Reactome:R-HSA-70885|MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|EC:1.1.1.31|Reactome:R-HSA-508473 go-plus.json http://purl.obolibrary.org/obo/GO_0008442 GO:0008441 biolink:MolecularActivity 3'(2'),5'-bisphosphate nucleotidase activity Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. Reactome:R-HSA-176606|Reactome:R-HSA-8953499|MetaCyc:325-BISPHOSPHATE-NUCLEOTIDASE-RXN|EC:3.1.3.7|RHEA:10040 go-plus.json 3'-phosphoadenylylsulfate 3'-phosphatase activity|3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity|DPNPase activity|adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity|3'(2'),5' bisphosphate nucleotidase activity|phosphoadenylate 3'-nucleotidase activity http://purl.obolibrary.org/obo/GO_0008441 GO:0008440 biolink:MolecularActivity inositol-1,4,5-trisphosphate 3-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+). Reactome:R-HSA-1855233|Reactome:R-HSA-1855153|MetaCyc:2.7.1.127-RXN|KEGG_REACTION:R03433|EC:2.7.1.127|RHEA:11020 go-plus.json ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity|IP3K activity|Ins(1,4,5)P3 3-kinase activity|inositol trisphosphate 3-kinase activity|1D-myo-inositol-trisphosphate 3-kinase activity|inositol-trisphosphate 3-kinase activity|IP3 3-kinase activity|ins(1,4,5)P(3) 3-kinase activity http://purl.obolibrary.org/obo/GO_0008440 CHEBI:58497 biolink:ChemicalSubstance N-acyl-L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58497 chebi_ph7_3 OBO:GOCHE_64909 biolink:OntologyClass substance with poison role go-plus.json http://purl.obolibrary.org/obo/GOCHE_64909 3_STAR CHEBI:58496 biolink:ChemicalSubstance N-acetyl-D-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58496 chebi_ph7_3 CHEBI:138107 biolink:ChemicalSubstance (3S)-3-hydroxy-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138107 chebi_ph7_3 CHEBI:58495 biolink:ChemicalSubstance (2S)-2-carbamoylpyrrolidin-1-ium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58495 chebi_ph7_3 CHEBI:138105 biolink:ChemicalSubstance (S)-6-acetamido-3-aminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138105 CHEBI:138109 biolink:ChemicalSubstance alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138109 CHEBI:58490 biolink:ChemicalSubstance (+)-8'-hydroxyabscisate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58490 chebi_ph7_3 GO:0033402 biolink:MolecularActivity UUC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UUC codon. go-plus.json TTC codon-amino acid adaptor activity|phenylalanine tRNA http://purl.obolibrary.org/obo/GO_0033402 PO:0020003 biolink:OntologyClass plant ovule A plant organ (PO:0009008) that has as parts a nucellus (PO:0020020) in which a female gametophyte (PO:0025279) is located, one or two integuments (PO:0020021), and a funicle (PO:0020006). go-plus.json óvulo vegetal (Spanish, exact)|胚珠 (Japanese, exact)|Poaceae ovule (narrow)|Zea ovule (narrow) http://purl.obolibrary.org/obo/PO_0020003 CHEBI:138100 biolink:ChemicalSubstance 2-[(9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl]-sn-glycero-3- phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138100 chebi_ph7_3 GO:0033401 biolink:MolecularActivity UUU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UUU codon. go-plus.json phenylalanine tRNA|TTT codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033401 GO:0033400 biolink:BiologicalProcess trans-zeatin metabolic process The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. go-plus.json trans-zeatin metabolism http://purl.obolibrary.org/obo/GO_0033400 CHEBI:138103 biolink:ChemicalSubstance inorganic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138103 PO:0020001 biolink:OntologyClass plant ovary placenta A portion of placenta tissue (PO:0025078) which is part of a plant ovary (PO:0009072), and to which plant ovary ovules (PO:0025490) are attached. go-plus.json Poaceae ovary placenta (narrow)|子房胎座 (Japanese, exact)|placenta de ovario (Spanish, exact)|Zea ovary placenta (narrow) http://purl.obolibrary.org/obo/PO_0020001 CHEBI:58499 biolink:ChemicalSubstance L-pyrrolysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58499 chebi_ph7_3 CHEBI:138102 biolink:ChemicalSubstance 4-(ADP-D-ribosyl)-L-aspartyl(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138102 chebi_ph7_3 CHEBI:138101 biolink:ChemicalSubstance 2-[(9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl]-sn-glycero-3- phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138101 chebi_ph7_3 CHEBI:58498 biolink:ChemicalSubstance 6-acetamido-3-aminohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58498 chebi_ph7_3 GO:0008459 biolink:MolecularActivity chondroitin 6-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. Reactome:R-HSA-2018682|RHEA:11108|EC:2.8.2.17|Reactome:R-HSA-3595175|MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN go-plus.json chondroitin 6-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity|3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity|chondroitin 6-sulphotransferase activity|terminal 6-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0008459 GO:0008458 biolink:MolecularActivity carnitine O-octanoyltransferase activity Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA. KEGG_REACTION:R03779|MetaCyc:CARNITINE-O-OCTANOYLTRANSFERASE-RXN|EC:2.3.1.137|RHEA:17177|Reactome:R-HSA-390281 go-plus.json medium-chain/long-chain carnitine acyltransferase activity|overt mitochondrial carnitine palmitoyltransferase|octanoyl-CoA:L-carnitine O-octanoyltransferase activity|easily solubilized mitochondrial carnitine palmitoyltransferase|carnitine medium-chain acyltransferase activity http://purl.obolibrary.org/obo/GO_0008458 GO:0008457 biolink:MolecularActivity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide. RHEA:23004|EC:2.4.1.149|MetaCyc:2.4.1.163-RXN go-plus.json UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|poly-N-acetyllactosamine extension enzyme activity http://purl.obolibrary.org/obo/GO_0008457 GO:0008456 biolink:MolecularActivity alpha-N-acetylgalactosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides. MetaCyc:3.2.1.49-RXN|RHEA:15085|EC:3.2.1.49 go-plus.json alpha-NAGA activity|N-acetyl-alpha-D-galactosaminidase activity|alpha-galactosidase B activity|N-acetyl-alpha-galactosaminidase activity|alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity|alpha-acetylgalactosaminidase activity http://purl.obolibrary.org/obo/GO_0008456 GO:0008455 biolink:MolecularActivity alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R. Reactome:R-HSA-975829|RHEA:12941|MetaCyc:2.4.1.143-RXN|EC:2.4.1.143|Reactome:R-HSA-4793955|Reactome:R-HSA-9694656 go-plus.json uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity|GnTII activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity|alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase II activity|uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase II activity|alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0008455 GO:0008454 biolink:MolecularActivity alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R. Reactome:R-HSA-9696980|Reactome:R-HSA-975903|MetaCyc:2.4.1.145-RXN|RHEA:16057|EC:2.4.1.145 go-plus.json alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|GnTIV activity|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|beta-acetylglucosaminyltransferase IV activity|N-acetylglucosaminyltransferase IV activity|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV http://purl.obolibrary.org/obo/GO_0008454 GO:0008453 biolink:MolecularActivity alanine-glyoxylate transaminase activity Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine. EC:2.6.1.44|RHEA:24248|Reactome:R-HSA-904864|Reactome:R-HSA-389684|MetaCyc:ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN go-plus.json alanine--glyoxylate aminotransferase activity|alanine-glyoxylate aminotransferase activity|alanine-glyoxylic aminotransferase activity|AGT activity|L-alanine-glycine transaminase activity|L-alanine:glyoxylate aminotransferase activity http://purl.obolibrary.org/obo/GO_0008453 GO:0008452 biolink:MolecularActivity RNA ligase activity Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another. go-plus.json http://purl.obolibrary.org/obo/GO_0008452 GO:0008451 biolink:MolecularActivity obsolete X-Pro aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide. go-plus.json aminopeptidase P|aminoacylproline aminopeptidase activity|proline aminopeptidase|Xaa-Pro aminopeptidase activity|X-Pro aminopeptidase activity http://purl.obolibrary.org/obo/GO_0008451 GO:0008450 biolink:MolecularActivity obsolete O-sialoglycoprotein endopeptidase activity OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated. go-plus.json O-sialoglycoprotein endopeptidase activity|sialoglycoproteinase activity|sialoglycoprotease activity|glycophorin A proteinase activity|glycoproteinase activity|glycoprotease activity http://purl.obolibrary.org/obo/GO_0008450 GO:0008460 biolink:MolecularActivity dTDP-glucose 4,6-dehydratase activity Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O. EC:4.2.1.46|MetaCyc:DTDPGLUCDEHYDRAT-RXN|KEGG_REACTION:R06513|RHEA:17221 go-plus.json dTDPglucose 4,6-hydro-lyase activity|TDP-glucose oxidoreductase activity|dTDP-glucose 4,6-hydro-lyase activity|thymidine diphosphoglucose oxidoreductase activity|dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)|dTDPglucose 4,6-dehydratase activity http://purl.obolibrary.org/obo/GO_0008460 CHEBI:58485 biolink:ChemicalSubstance 3-hydroxy-16-methoxy-2,3-dihydrotabersoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58485 chebi_ph7_3 CHEBI:58484 biolink:ChemicalSubstance 1D-myo-inositol 1,2-cyclic phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58484 chebi_ph7_3 NCBITaxon:224324 biolink:OrganismalEntity Aquifex aeolicus VF5 go-plus.json Aquifex aeolicus str. VF5 http://purl.obolibrary.org/obo/NCBITaxon_224324 CHEBI:58483 biolink:ChemicalSubstance 2-C-methyl-D-erythritol 2,4-cyclic diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58483 chebi_ph7_3 CHEBI:58482 biolink:ChemicalSubstance (RS)-norcoclaurinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58482 chebi_ph7_3 PR:000009799 biolink:Protein leukemia inhibitory factor A protein that is a translation product of the human LIF gene or a 1:1 ortholog thereof. go-plus.json MLPLI|D factor|LIF|melanoma-derived LPL inhibitor|emfilermin|differentiation-stimulating factor|HILDA http://purl.obolibrary.org/obo/PR_000009799 CHEBI:58481 biolink:ChemicalSubstance (RS)-coclaurinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58481 chebi_ph7_3 CHEBI:58480 biolink:ChemicalSubstance N-[(R)-pantothenoyl]-L-cysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58480 chebi_ph7_3 CHEBI:138111 biolink:ChemicalSubstance (3S)-3-hydroxy-L-aspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138111 chebi_ph7_3 PR:000019110 biolink:Protein beta-2-microglobulin proteolytic cleavage product A beta-2-microglobulin that has been processed by proteolytic cleavage. go-plus.json B2M/ClvPrd http://purl.obolibrary.org/obo/PR_000019110 CHEBI:138110 biolink:ChemicalSubstance 16(S)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_138110 CHEBI:58489 biolink:ChemicalSubstance 5-guanidino-2-oxopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58489 chebi_ph7_3 CHEBI:138114 biolink:ChemicalSubstance O-guanylyl-L-tyrosine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138114 chebi_ph7_3 CHEBI:58488 biolink:ChemicalSubstance 3-epi-3-hydroxymugineate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58488 chebi_ph7_3 CHEBI:138113 biolink:ChemicalSubstance O-adenyl-L-threonine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138113 chebi_ph7_3 CHEBI:58487 biolink:ChemicalSubstance 2'-deoxymugineate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58487 chebi_ph7_3 CHEBI:138112 biolink:ChemicalSubstance chondroitin 4',6'-disulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138112 chebi_ph7_3 GO:0008429 biolink:MolecularActivity phosphatidylethanolamine binding Binding to a phosphatidylethanolamine, a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. go-plus.json http://purl.obolibrary.org/obo/GO_0008429 GO:0008428 biolink:MolecularActivity ribonuclease inhibitor activity Binds to and stops, prevents or reduces the activity of ribonuclease. go-plus.json http://purl.obolibrary.org/obo/GO_0008428 GO:0008427 biolink:MolecularActivity calcium-dependent protein kinase inhibitor activity Binds to and stops, prevents or reduces the activity of a calcium-dependent protein kinase. go-plus.json http://purl.obolibrary.org/obo/GO_0008427 GO:0008426 biolink:MolecularActivity protein kinase C inhibitor activity Binds to and stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein. go-plus.json PKC inhibitor activity|diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity|diacylglycerol-activated phospholipid-dependent PKC inhibitor activity http://purl.obolibrary.org/obo/GO_0008426 CHEBI:128769 biolink:ChemicalSubstance isopentenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_128769 chebi_ph7_3 GO:0008425 biolink:MolecularActivity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. EC:2.1.1.- go-plus.json 2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity|coenzyme Q biosynthetic process methyltransferase activity|coenzyme Q biosynthesis methyltransferase activity|ubiquinone biosynthesis methyltransferase activity|ubiquinone biosynthetic process methyltransferase activity http://purl.obolibrary.org/obo/GO_0008425 GO:0008424 biolink:MolecularActivity glycoprotein 6-alpha-L-fucosyltransferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+). Reactome:R-HSA-1028788|MetaCyc:2.4.1.68-RXN|EC:2.4.1.68|Reactome:R-HSA-9696980|KEGG_REACTION:R05988|RHEA:12985 go-plus.json GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity|GDPfucose-glycoprotein fucosyltransferase activity|FucT|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity|GDP-L-fucose--glycoprotein fucosyltransferase activity|GDP-fucose--glycoprotein fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity|guanosine diphosphofucose--glycoprotein fucosyltransferase activity|glycoprotein fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0008424 GO:0008423 biolink:MolecularActivity obsolete bleomycin hydrolase activity OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. go-plus.json aminopeptidase C (Lactococcus lactis)|bleomycin hydrolase activity http://purl.obolibrary.org/obo/GO_0008423 GO:0008422 biolink:MolecularActivity beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. MetaCyc:3.2.1.21-RXN|EC:3.2.1.21 go-plus.json beta-glucoside glucohydrolase activity|primeverosidase activity|limarase activity|salicilinase activity|aryl-beta-glucosidase activity|beta-D-glucoside glucohydrolase activity|beta-1,6-glucosidase activity|amygdalase activity|cellobiase activity|emulsin|p-nitrophenyl beta-glucosidase activity|gentobiase activity|cytokine beta-glucosidase activity|gentiobiase activity|beta-D-glucosidase activity|amygdalinase|arbutinase activity|elaterase activity http://purl.obolibrary.org/obo/GO_0008422 GO:0008421 biolink:MolecularActivity long-chain fatty-acyl-glutamate deacylase activity Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate. MetaCyc:3.5.1.55-RXN|RHEA:17517|EC:3.5.1.55 go-plus.json long-chain acylglutamate amidase activity|long-chain aminoacylase activity|long-chain-fatty-acyl-glutamate deacylase activity|N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity|long-chain fatty acyl-glutamate deacylase activity http://purl.obolibrary.org/obo/GO_0008421 GO:0008420 biolink:MolecularActivity RNA polymerase II CTD heptapeptide repeat phosphatase activity Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate. go-plus.json RNA polymerase II carboxy-terminal domain phosphatase activity|CTD phosphatase activity http://purl.obolibrary.org/obo/GO_0008420 CHEBI:58475 biolink:ChemicalSubstance 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58475 chebi_ph7_3 CHEBI:58474 biolink:ChemicalSubstance 3,6-dioxocyclohexa-1,4-dien-1-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58474 chebi_ph7_3 CHEBI:58473 biolink:ChemicalSubstance codeinone(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58473 chebi_ph7_3 CHEBI:58472 biolink:ChemicalSubstance beta-D-mannosyldiacetylchitobiosyldiphosphodolichol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58472 chebi_ph7_3 CHEBI:58471 biolink:ChemicalSubstance bis(beta-glucosyluronate)bilirubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_58471 chebi_ph7_3 CHEBI:58470 biolink:ChemicalSubstance apigenin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58470 chebi_ph7_3 CHEBI:58479 biolink:ChemicalSubstance N-formimidoylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58479 chebi_ph7_3 CHEBI:58478 biolink:ChemicalSubstance 2-formamido-N(1)-(5-O-phosphonato-D-ribosyl)acetamidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58478 chebi_ph7_3 CHEBI:58477 biolink:ChemicalSubstance N(omega)-phosphonato-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58477 chebi_ph7_3 CHEBI:58476 biolink:ChemicalSubstance (2S)-2-hydroxy-2-methyl-3-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58476 chebi_ph7_3 GO:0008439 biolink:MolecularActivity obsolete monophenol monooxygenase activator activity OBSOLETE. Increases the activity of the enzyme monophenol monooxygenase. go-plus.json prophenol oxidase activator|monophenol monooxygenase activator activity http://purl.obolibrary.org/obo/GO_0008439 GO:0008438 biolink:MolecularActivity obsolete 1-phosphatidylinositol-5-phosphate kinase OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide. go-plus.json 1-phosphatidylinositol-5-phosphate kinase http://purl.obolibrary.org/obo/GO_0008438 GO:0008437 biolink:MolecularActivity thyrotropin-releasing hormone activity The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. go-plus.json TRH activity|thyrotropin releasing hormone activity http://purl.obolibrary.org/obo/GO_0008437 GO:0008436 biolink:MolecularActivity obsolete heterogeneous nuclear ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json heterogeneous nuclear ribonucleoprotein|hnRNP http://purl.obolibrary.org/obo/GO_0008436 GO:0008435 biolink:MolecularActivity obsolete anticoagulant activity OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation. go-plus.json anticoagulant activity http://purl.obolibrary.org/obo/GO_0008435 GO:0008434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008434 GO:0008433 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008433 GO:0008432 biolink:MolecularActivity JUN kinase binding Binding to JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family. go-plus.json JNK binding http://purl.obolibrary.org/obo/GO_0008432 GO:0008431 biolink:MolecularActivity vitamin E binding Binding to a vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. go-plus.json tocopherol binding|alpha-tocopherol binding http://purl.obolibrary.org/obo/GO_0008431 CHEBI:128770 biolink:ChemicalSubstance 12,18-dihydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_128770 GO:0008430 biolink:MolecularActivity selenium binding Binding to a selenium (Se) ion. go-plus.json http://purl.obolibrary.org/obo/GO_0008430 CHEBI:58464 biolink:ChemicalSubstance nucleoside 3',5'-cyclic phosphate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58464 chebi_ph7_3 CHEBI:58463 biolink:ChemicalSubstance (7S)-salutaridinol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58463 chebi_ph7_3 CHEBI:58462 biolink:ChemicalSubstance 7,8-dihydroneopterin 3'-triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58462 chebi_ph7_3 CHEBI:58461 biolink:ChemicalSubstance 17-O-deacetylvindolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58461 chebi_ph7_3 CHEBI:58460 biolink:ChemicalSubstance 13-(2-methylcrotonoyloxy)lupaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58460 chebi_ph7_3 CHEBI:58469 biolink:ChemicalSubstance 1D-myo-inositol 4-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58469 chebi_ph7_3 CHEBI:58468 biolink:ChemicalSubstance 3-aminoalanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58468 chebi_ph7_3 CHEBI:58467 biolink:ChemicalSubstance 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58467 chebi_ph7_3 CHEBI:58466 biolink:ChemicalSubstance 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58466 chebi_ph7_3 CHEBI:58465 biolink:ChemicalSubstance dermatan sulfate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58465 chebi_ph7_3 GO:0008409 biolink:MolecularActivity 5'-3' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end. Reactome:R-HSA-5358619|Reactome:R-HSA-5358599 go-plus.json http://purl.obolibrary.org/obo/GO_0008409 GO:0008408 biolink:MolecularActivity 3'-5' exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. Reactome:R-HSA-3245943 go-plus.json 3'-5'-exonuclease activity http://purl.obolibrary.org/obo/GO_0008408 GO:0008407 biolink:BiologicalProcess chaeta morphogenesis The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell. go-plus.json bristle morphogenesis http://purl.obolibrary.org/obo/GO_0008407 GO:0008406 biolink:BiologicalProcess gonad development The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. go-plus.json gonadogenesis http://purl.obolibrary.org/obo/GO_0008406 GO:0008405 biolink:MolecularActivity arachidonic acid 11,12-epoxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid. RHEA:51480 go-plus.json cytochrome P450 CYP2C38 http://purl.obolibrary.org/obo/GO_0008405 GO:0008404 biolink:MolecularActivity arachidonic acid 14,15-epoxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid. RHEA:51472 go-plus.json cytochrome P450 CYP2C29|cytochrome P450 CYP2C39 http://purl.obolibrary.org/obo/GO_0008404 GO:0008403 biolink:MolecularActivity 25-hydroxycholecalciferol-24-hydroxylase activity Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol. go-plus.json 25-hydroxyvitamin D3 24-hydroxylase activity|cytochrome P450 CYP24 http://purl.obolibrary.org/obo/GO_0008403 GO:0008402 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008402 GO:0008401 biolink:MolecularActivity retinoic acid 4-hydroxylase activity Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid. Reactome:R-HSA-211923|Reactome:R-HSA-5602063|Reactome:R-HSA-212007|Reactome:R-HSA-211874|Reactome:R-HSA-5362525|Reactome:R-HSA-5602050 go-plus.json cytochrome P450 CYP261 http://purl.obolibrary.org/obo/GO_0008401 GO:0008400 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008400 CHEBI:58453 biolink:ChemicalSubstance 5-amino-6-(5-phospho-D-ribosylamino)uracil(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58453 chebi_ph7_3 CHEBI:58452 biolink:ChemicalSubstance 4-(phosphonatooxy)-L-threonine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58452 chebi_ph7_3 CHEBI:34485 biolink:ChemicalSubstance 8(R)-HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34485 CHEBI:58451 biolink:ChemicalSubstance pyridoxamine 5'-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58451 chebi_ph7_3 CHEBI:58450 biolink:ChemicalSubstance adenosine 5'-tetraphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58450 chebi_ph7_3 CHEBI:34487 biolink:ChemicalSubstance 8(S)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34487 PO:0020047 biolink:OntologyClass microsporocyte A sporocyte (PO:0006204) that produces four haploid (1n) microspores (PO:0020048). go-plus.json microsporocito (Spanish, exact)|小胞子母細胞 (Japanese, exact)|Zea microsporocyte (narrow)|pollen mother cell (related)|PMC (related)|Poaceae microsporocyte (narrow)|microspore mother cell (related) http://purl.obolibrary.org/obo/PO_0020047 PO:0020049 biolink:OntologyClass leaflet A cardinal organ part (PO:0025001) that is one of the ultimate segments of a compound leaf (PO:0020043). go-plus.json pinnule (narrow)|小葉 (Japanese, exact)|pinnae (narrow)|folíolo (Spanish, exact)|pinna (narrow) http://purl.obolibrary.org/obo/PO_0020049 CHEBI:58459 biolink:ChemicalSubstance pyrroloquinoline quinol(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58459 PO:0020048 biolink:OntologyClass microspore The smaller, in general, of the two kinds of spores produced after meiosis in the life cycle of a heterosporous plant, and on germination giving rise to the male gametophyte. go-plus.json 小胞子 (Japanese, exact)|Poaceae microspore (narrow)|microspora (Spanish, exact)|Zea microspore (narrow) http://purl.obolibrary.org/obo/PO_0020048 CHEBI:58458 biolink:ChemicalSubstance (R)-2-hydroxypropyl-CoM(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58458 chebi_ph7_3 PO:0020043 biolink:OntologyClass compound leaf A leaf having two or more distinct leaflets that are evident as such from early in development. go-plus.json 複葉 (Japanese, exact)|hoja compuesta (Spanish, exact) http://purl.obolibrary.org/obo/PO_0020043 CHEBI:58457 biolink:ChemicalSubstance N(1)-(5-phospho-D-ribosyl)glycinamide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58457 chebi_ph7_3 PO:0020042 biolink:OntologyClass simple leaf A leaf in which the lamina is undivided. go-plus.json hoja simple (Spanish, exact)|単葉 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020042 CHEBI:58456 biolink:ChemicalSubstance 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58456 chebi_ph7_3 CHEBI:58455 biolink:ChemicalSubstance L-2-aminohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58455 chebi_ph7_3 CHEBI:58454 biolink:ChemicalSubstance kynurenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58454 chebi_ph7_3 CHEBI:34483 biolink:ChemicalSubstance 7-hydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_34483 chebi_ph7_3 PO:0020041 biolink:OntologyClass stipule A cardinal organ part that is an appendage at the base of a vascular leaf. go-plus.json 托葉 (Japanese, exact)|estípula (Spanish, exact) http://purl.obolibrary.org/obo/PO_0020041 GO:0008419 biolink:MolecularActivity RNA lariat debranching enzyme activity Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0008419 GO:0008418 biolink:MolecularActivity protein-N-terminal asparagine amidohydrolase activity Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0008418 GO:0008417 biolink:MolecularActivity fucosyltransferase activity Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. Reactome:R-HSA-9033949 go-plus.json http://purl.obolibrary.org/obo/GO_0008417 GO:0008416 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008416 PR:000020135 biolink:Protein hepatocyte growth factor proteolytic cleavage product A hepatocyte growth factor that has been processed by proteolytic cleavage. go-plus.json HGF/ClvPrd http://purl.obolibrary.org/obo/PR_000020135 GO:0008415 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008415 GO:0008414 biolink:MolecularActivity CDP-alcohol phosphotransferase activity Catalysis of the transfer of a CDP-alcohol group from one compound to another. go-plus.json http://purl.obolibrary.org/obo/GO_0008414 GO:0008413 biolink:MolecularActivity 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) + phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription. EC:3.6.1.69|RHEA:60032 go-plus.json 8-oxo-7,8-dihydroguanine triphosphatase activity|8-oxo-7,8-dihydroguanosine triphosphatase activity|8-oxo-GTPase activity|7,8-dihydro-8-oxoguanine-triphosphatase activity http://purl.obolibrary.org/obo/GO_0008413 GO:0008412 biolink:MolecularActivity 4-hydroxybenzoate octaprenyltransferase activity Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. EC:2.5.1.39|MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|RHEA:27782 go-plus.json para-hydroxybenzoate:polyprenyltransferase activity|para-hydroxybenzoate transferase activity|PHB polyprenyl diphosphate transferase activity|para-hydroxybenzoate-polyprenyl diphosphate transferase activity|4-HB polyprenyltransferase activity http://purl.obolibrary.org/obo/GO_0008412 GO:0008411 biolink:MolecularActivity 4-hydroxybutyrate CoA-transferase activity Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate. go-plus.json http://purl.obolibrary.org/obo/GO_0008411 CHEBI:128754 biolink:ChemicalSubstance GDP-valienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_128754 CHEBI:128753 biolink:ChemicalSubstance (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_128753 chebi_ph7_3 GO:0008410 biolink:MolecularActivity CoA-transferase activity Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor). Reactome:R-HSA-70713|EC:2.8.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0008410 CHEBI:58442 biolink:ChemicalSubstance pyrroloquinoline quinone(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58442 chebi_ph7_3 CHEBI:34497 biolink:ChemicalSubstance 9(S)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34497 CHEBI:58441 biolink:ChemicalSubstance L-2-aminopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58441 chebi_ph7_3 CHEBI:34496 biolink:ChemicalSubstance 9(S)-HODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34496 CHEBI:58440 biolink:ChemicalSubstance quinoline-4-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58440 chebi_ph7_3 CHEBI:34498 biolink:ChemicalSubstance 9(S)-HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34498 NCBITaxon:190485 biolink:OrganismalEntity Xanthomonas campestris pv. campestris str. ATCC 33913 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_190485 CHEBI:58448 biolink:ChemicalSubstance L-thyroxine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58448 chebi_ph7_3 CHEBI:58447 biolink:ChemicalSubstance isovitexin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58447 chebi_ph7_3 CHEBI:34490 biolink:ChemicalSubstance 8,9-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_34490 CHEBI:58446 biolink:ChemicalSubstance 13-hydroxylupaninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58446 chebi_ph7_3 CHEBI:58445 biolink:ChemicalSubstance anserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58445 chebi_ph7_3 PO:0020031 biolink:OntologyClass radicle An embryo root (PO:0000045) that is the basal continuation of a hypocotyl (PO:0020100) in a plant embryo (PO:0009009) or a seedling (PO:0000003). go-plus.json radícula (Spanish, exact)|幼根 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020031 CHEBI:58444 biolink:ChemicalSubstance 1-(sn-glycero-3-O-phosphonato)-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_58444 chebi_ph7_3 CHEBI:34494 biolink:ChemicalSubstance 9(10)-EpOME go-plus.json http://purl.obolibrary.org/obo/CHEBI_34494 CHEBI:58443 biolink:ChemicalSubstance SAICAR(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58443 chebi_ph7_3 PO:0020030 biolink:OntologyClass cotyledon A vascular leaf (PO:0009025) formed at the first shoot node (PO:0005004) of a plant embryo (PO:0009009) or a seedling (PO:0000003). go-plus.json cotiledón (Spanish, exact)|seed leaf (exact)|子葉 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020030 PR:000020124 biolink:Protein orexin proteolytic cleavage product An orexin that has been processed by proteolytic cleavage. go-plus.json HCRT/ClvPrd http://purl.obolibrary.org/obo/PR_000020124 CHEBI:58431 biolink:ChemicalSubstance jasmonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58431 chebi_ph7_3 UBERON:2001544 biolink:AnatomicalEntity sublingual cartilage Pharyngeal arch cartilage that is the median cartilage of the ventral hyoid arch, generally lying between the paired ventral hypohyals. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001544 CHEBI:58430 biolink:ChemicalSubstance (S)-2-hydroxypropyl-CoM(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58430 chebi_ph7_3 CHEBI:58439 biolink:ChemicalSubstance UDP-D-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58439 chebi_ph7_3 CHEBI:58438 biolink:ChemicalSubstance thiaminium carboxylate betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58438 chebi_ph7_3 CHEBI:58437 biolink:ChemicalSubstance deamido-NAD(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58437 chebi_ph7_3 CHEBI:58436 biolink:ChemicalSubstance phosphatidyl-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58436 chebi_ph7_3 PO:0020021 biolink:OntologyClass integument A portion of plant tissue (PO:0009007) that usually covers a plant ovule (PO:0020003), enveloping a nucellus (PO:0020020) and forming a micropyle (PO:0020025) at the apex. go-plus.json Zea integument (narrow)|integumento (Spanish, exact)|Poaceae integument (narrow)|珠皮 (Japanese, exact)|portion of integument tissue (exact) http://purl.obolibrary.org/obo/PO_0020021 CHEBI:58435 biolink:ChemicalSubstance 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58435 chebi_ph7_3 CHEBI:58434 biolink:ChemicalSubstance (2Z,4E)-4-hydroxymuconic semialdehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58434 chebi_ph7_3 CHEBI:58433 biolink:ChemicalSubstance 1D-myo-inositol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58433 chebi_ph7_3 CHEBI:58432 biolink:ChemicalSubstance histaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58432 chebi_ph7_3 CHEBI:58429 biolink:ChemicalSubstance alpha,alpha-trehalose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58429 chebi_ph7_3 CHEBI:58420 biolink:ChemicalSubstance cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58420 chebi_ph7_3 CHEBI:34477 biolink:ChemicalSubstance 6beta-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_34477 chebi_ph7_3 PO:0020019 biolink:OntologyClass megaspore The larger, in general, of the two kinds of spores produced after meiosis in the life cycle of a heterosporous plant, and on germination giving rise to the female gametophyte (embryo sac). go-plus.json 大胞子 (Japanese, exact)|Poaceae megaspore (narrow)|Zea megaspore (narrow)|megaspora (Spanish, exact)|macrospore (related) http://purl.obolibrary.org/obo/PO_0020019 CHEBI:58427 biolink:ChemicalSubstance N-acetyl-D-glucosaminyldiphosphodolichol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58427 chebi_ph7_3 NCBITaxon:224308 biolink:OrganismalEntity Bacillus subtilis subsp. subtilis str. 168 go-plus.json Bacillus subtilis 168|Bacillus subtilis subsp. subtilis str. BGSC 1A700|Bacillus subtilis subsp. subtilis 168 http://purl.obolibrary.org/obo/NCBITaxon_224308 PR:000019130 biolink:Protein brain-derived neurotrophic factor proteolytic cleavage product A brain-derived neurotrophic factor that has been processed by proteolytic cleavage. go-plus.json BDNF/ClvPrd http://purl.obolibrary.org/obo/PR_000019130 CHEBI:58426 biolink:ChemicalSubstance N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58426 chebi_ph7_3 CHEBI:58425 biolink:ChemicalSubstance 5-oxo-4,5-dihydro-2-furylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58425 chebi_ph7_3 CHEBI:58424 biolink:ChemicalSubstance 1-(5-phospho-D-ribosyl)-ATP(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58424 chebi_ph7_3 CHEBI:58423 biolink:ChemicalSubstance UDP-D-galactofuranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58423 chebi_ph7_3 CHEBI:58422 biolink:ChemicalSubstance chondroitin 4'-sulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58422 chebi_ph7_3 CHEBI:58421 biolink:ChemicalSubstance 5-amino-6-(5-phosphoribitylamino)uracil(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58421 chebi_ph7_3 CHEBI:138191 biolink:ChemicalSubstance 3'-end 3'-(N-acyl-L-alpha-aminoacyl)adenylyl(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138191 chebi_ph7_3 CHEBI:138195 biolink:ChemicalSubstance 1,2-diheptanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138195 chebi_ph7_3 CHEBI:138194 biolink:ChemicalSubstance 1,2-dihexanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138194 chebi_ph7_3 CHEBI:138193 biolink:ChemicalSubstance (2R,5S)-2,5-diaminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138193 GO:0033482 biolink:BiologicalProcess D-galacturonate biosynthetic process The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. go-plus.json D-galacturonate synthesis|D-galacturonate biosynthesis|D-galacturonate formation|D-galacturonate anabolism http://purl.obolibrary.org/obo/GO_0033482 GO:0033481 biolink:BiologicalProcess galacturonate biosynthetic process The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid. go-plus.json galacturonate biosynthesis|galacturonate anabolism|galacturonate synthesis|galacturonate formation http://purl.obolibrary.org/obo/GO_0033481 GO:0033480 biolink:BiologicalProcess UDP-D-galacturonate biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-4 go-plus.json UDP-D-galacturonate anabolism|UDP-D-galacturonate synthesis|UDP-D-galacturonate formation|UDP-D-galacturonate biosynthesis http://purl.obolibrary.org/obo/GO_0033480 CHEBI:138188 biolink:ChemicalSubstance (2R,3R)-dihydroflavonol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138188 chebi_ph7_3 GO:0033489 biolink:BiologicalProcess cholesterol biosynthetic process via desmosterol The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol. MetaCyc:PWY66-4 go-plus.json cholesterol anabolism via desmosterol|cholesterol synthesis via desmosterol|cholesterol formation via desmosterol|cholesterol biosynthesis via desmosterol http://purl.obolibrary.org/obo/GO_0033489 GO:0033488 biolink:BiologicalProcess cholesterol biosynthetic process via 24,25-dihydrolanosterol The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol. MetaCyc:PWY66-3 go-plus.json cholesterol anabolism via 24,25-dihydrolanosterol|cholesterol synthesis via 24,25-dihydrolanosterol|cholesterol formation via 24,25-dihydrolanosterol|cholesterol biosynthesis via 24,25-dihydrolanosterol http://purl.obolibrary.org/obo/GO_0033488 GO:0033487 biolink:BiologicalProcess pelargonidin 3-O-glucoside biosynthetic process The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits. MetaCyc:PWY-5125 go-plus.json pelargonidin 3-O-glucoside biosynthesis|pelargonidin 3-O-glucoside anabolism|pelargonidin 3-O-glucoside synthesis|pelargonidin 3-O-glucoside formation http://purl.obolibrary.org/obo/GO_0033487 GO:0033486 biolink:BiologicalProcess delphinidin 3-O-glucoside biosynthetic process The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits. MetaCyc:PWY-5153 go-plus.json delphinidin 3-O-glucoside anabolism|delphinidin 3-O-glucoside synthesis|delphinidin 3-O-glucoside formation|delphinidin 3-O-glucoside biosynthesis http://purl.obolibrary.org/obo/GO_0033486 GO:0033485 biolink:BiologicalProcess cyanidin 3-O-glucoside biosynthetic process The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits. MetaCyc:PWY-5125 go-plus.json cyanidin 3-O-glucoside anabolism|cyanidin 3-O-glucoside synthesis|cyanidin 3-O-glucoside formation|cyanidin 3-O-glucoside biosynthesis http://purl.obolibrary.org/obo/GO_0033485 GO:0033484 biolink:BiologicalProcess nitric oxide homeostasis A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell. go-plus.json NO homeostasis http://purl.obolibrary.org/obo/GO_0033484 GO:0033483 biolink:BiologicalProcess gas homeostasis A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0033483 GO:0033471 biolink:BiologicalProcess GDP-L-galactose metabolic process The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-L-galactose metabolism http://purl.obolibrary.org/obo/GO_0033471 GO:0033470 biolink:BiologicalProcess gibberellin 12 biosynthetic process The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid. MetaCyc:PWY-5034 go-plus.json GA12 biosynthetic process|gibberellin A12 biosynthetic process|gibberellin 12 biosynthesis|gibberellin 12 anabolism|gibberellin 12 synthesis|gibberellin 12 formation http://purl.obolibrary.org/obo/GO_0033470 GO:0033479 biolink:BiologicalProcess UDP-D-galacturonate metabolic process The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate. go-plus.json UDP-D-galacturonate metabolism http://purl.obolibrary.org/obo/GO_0033479 CHEBI:138199 biolink:ChemicalSubstance 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138199 chebi_ph7_3 GO:0033478 biolink:BiologicalProcess UDP-rhamnose metabolic process The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate. MetaCyc:PWY-3261 go-plus.json UDP-rhamnose metabolism http://purl.obolibrary.org/obo/GO_0033478 CHEBI:138198 biolink:ChemicalSubstance 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138198 chebi_ph7_3 GO:0033477 biolink:BiologicalProcess S-methylmethionine metabolic process The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle. go-plus.json S-methylmethionine metabolism http://purl.obolibrary.org/obo/GO_0033477 CHEBI:138197 biolink:ChemicalSubstance 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138197 chebi_ph7_3 CHEBI:138196 biolink:ChemicalSubstance 19-hydroxyleukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_138196 GO:0033476 biolink:BiologicalProcess indoleacetic acid ester conjugate biosynthetic process The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond. MetaCyc:PWY-1741 go-plus.json indoleacetic acid ester conjugate anabolism|indoleacetic acid ester conjugate synthesis|indole acetic acid ester conjugate biosynthetic process|indole acetic acid ester conjugate biosynthesis|indoleacetic acid ester conjugate formation|indoleacetic acid ester conjugate biosynthesis|IAA ester conjugate biosynthetic process http://purl.obolibrary.org/obo/GO_0033476 GO:0033475 biolink:BiologicalProcess indoleacetic acid amide conjugate biosynthetic process The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond. MetaCyc:PWY-1782 go-plus.json indoleacetic acid amide conjugate synthesis|indoleacetic acid amide conjugate formation|indoleacetic acid amide conjugate biosynthesis|IAA amide conjugate biosynthetic process|indole acetic acid amide conjugate biosynthetic process|indole acetic acid amide conjugate biosynthesis|indoleacetic acid amide conjugate anabolism http://purl.obolibrary.org/obo/GO_0033475 GO:0033474 biolink:BiologicalProcess indoleacetic acid conjugate biosynthetic process The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule. go-plus.json indoleacetic acid conjugate formation|IAA conjugate biosynthetic process|indoleacetic acid conjugate biosynthesis|indole acetic acid conjugate biosynthetic process|indole acetic acid conjugate biosynthesis|indoleacetic acid conjugate anabolism|indoleacetic acid conjugate synthesis http://purl.obolibrary.org/obo/GO_0033474 GO:0033473 biolink:BiologicalProcess indoleacetic acid conjugate metabolic process The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule. go-plus.json indoleacetic acid conjugate metabolism|IAA conjugate metabolic process|indole acetic acid conjugate metabolic process|indole acetic acid conjugate metabolism http://purl.obolibrary.org/obo/GO_0033473 GO:0033472 biolink:BiologicalProcess GDP-L-galactose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate. MetaCyc:PWY-5115 go-plus.json GDP-L-galactose biosynthesis|GDP-L-galactose anabolism|GDP-L-galactose synthesis|GDP-L-galactose formation http://purl.obolibrary.org/obo/GO_0033472 CHEBI:138171 biolink:ChemicalSubstance pApA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138171 chebi_ph7_3 GO:0033469 biolink:BiologicalProcess gibberellin 12 metabolic process The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid. go-plus.json gibberellin 12 metabolism|gibberellin A12 metabolic process|GA12 metabolic process http://purl.obolibrary.org/obo/GO_0033469 GO:0033460 biolink:MolecularActivity GAG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GAG codon. go-plus.json glutamic acid tRNA http://purl.obolibrary.org/obo/GO_0033460 GO:0033468 biolink:BiologicalProcess CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate. MetaCyc:PWY-1269|MetaCyc:PWY-5111|MetaCyc:KDOSYN-PWY go-plus.json CMP-keto-3-deoxy-D-manno-octulosonic acid anabolism|CMP-keto-3-deoxy-D-manno-octulosonic acid synthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid formation|CMP-KDO biosynthetic process|CMP-KDO biosynthesis|CMP-ketodeoxyoctanoate biosynthetic process http://purl.obolibrary.org/obo/GO_0033468 CHEBI:138166 biolink:ChemicalSubstance nezukol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138166 chebi_ph7_3 GO:0033467 biolink:BiologicalProcess CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate. go-plus.json CMP-keto-3-deoxy-D-manno-octulosonic acid metabolism|CMP-KDO metabolic process|CMP-ketodeoxyoctanoate metabolic process http://purl.obolibrary.org/obo/GO_0033467 CHEBI:138165 biolink:ChemicalSubstance (+)-(2S,3R,9R)-pristinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138165 chebi_ph7_3 GO:0033466 biolink:BiologicalProcess trans-zeatin biosynthetic process The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. MetaCyc:PWY-2681 go-plus.json trans-zeatin biosynthesis|trans-zeatin anabolism|trans-zeatin synthesis|trans-zeatin formation http://purl.obolibrary.org/obo/GO_0033466 GO:0033465 biolink:BiologicalProcess cis-zeatin biosynthetic process The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. MetaCyc:PWY-2781 go-plus.json cis-zeatin anabolism|cis-zeatin synthesis|cis-zeatin formation|cis-zeatin biosynthesis http://purl.obolibrary.org/obo/GO_0033465 GO:0033464 biolink:MolecularActivity GGG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GGG codon. go-plus.json glycine tRNA http://purl.obolibrary.org/obo/GO_0033464 GO:0033463 biolink:MolecularActivity GGA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GGA codon. go-plus.json glycine tRNA http://purl.obolibrary.org/obo/GO_0033463 GO:0033462 biolink:MolecularActivity GGC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GGC codon. go-plus.json glycine tRNA http://purl.obolibrary.org/obo/GO_0033462 GO:0033461 biolink:MolecularActivity GGU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GGU codon. go-plus.json glycine tRNA|GGT codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033461 CHEBI:138167 biolink:ChemicalSubstance 5-hydroxy-alpha-gurjunene go-plus.json http://purl.obolibrary.org/obo/CHEBI_138167 chebi_ph7_3 GO:0033459 biolink:MolecularActivity GAA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GAA codon. go-plus.json glutamic acid tRNA http://purl.obolibrary.org/obo/GO_0033459 CHEBI:83408 biolink:ChemicalSubstance sn-glycerophosphodiester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83408 chebi_ph7_3 GO:0033458 biolink:MolecularActivity GAC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GAC codon. go-plus.json aspartic acid tRNA http://purl.obolibrary.org/obo/GO_0033458 CHEBI:83407 biolink:ChemicalSubstance 4-(phosphooxymethyl)-2-furancarboxaldehyde(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83407 chebi_ph7_3 CHEBI:83403 biolink:ChemicalSubstance monochlorobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_83403 CHEBI:83402 biolink:ChemicalSubstance nucleoside 3',5'-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83402 chebi_ph7_3 CHEBI:83401 biolink:ChemicalSubstance anionic tRNA polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_83401 chebi_ph7_3 CHEBI:83400 biolink:ChemicalSubstance RNA polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83400 chebi_ph7_3 CHEBI:138177 biolink:ChemicalSubstance 4-unsubstituted 3-hydroxyanthocyanidin betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_138177 chebi_ph7_3 GO:0033457 biolink:MolecularActivity GAU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GAU codon. go-plus.json aspartic acid tRNA|GAT codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033457 GO:0033456 biolink:MolecularActivity GCG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GCG codon. go-plus.json alanine tRNA http://purl.obolibrary.org/obo/GO_0033456 CHEBI:138176 biolink:ChemicalSubstance (2R,3S,4S)-leucoanthocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_138176 chebi_ph7_3 GO:0033455 biolink:MolecularActivity GCA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GCA codon. go-plus.json alanine tRNA http://purl.obolibrary.org/obo/GO_0033455 CHEBI:138175 biolink:ChemicalSubstance O-[S-(L-alpha-aminoacyl)pantetheine-4'-phosphoryl]serine zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138175 chebi_ph7_3 GO:0033454 biolink:MolecularActivity GCC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GCC codon. go-plus.json alanine tRNA http://purl.obolibrary.org/obo/GO_0033454 GO:0033453 biolink:MolecularActivity GCU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GCU codon. go-plus.json alanine tRNA|GCT codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033453 GO:0033452 biolink:MolecularActivity GUG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUG codon. go-plus.json valine tRNA|GTG codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033452 GO:0033451 biolink:MolecularActivity GUA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUA codon. go-plus.json valine tRNA|GTA codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033451 GO:0033450 biolink:MolecularActivity GUC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUC codon. go-plus.json valine tRNA|GTC codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033450 CHEBI:138178 biolink:ChemicalSubstance (4S)-2,3-dehydroflavan-3,4-diol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138178 chebi_ph7_3 GO:0033449 biolink:MolecularActivity GUU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUU codon. go-plus.json GTT codon-amino acid adaptor activity|valine tRNA http://purl.obolibrary.org/obo/GO_0033449 CHEBI:138150 biolink:ChemicalSubstance D-tagatopyranose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_138150 chebi_ph7_3 CHEBI:83419 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83419 chebi_ph7_3 GO:0033448 biolink:MolecularActivity AGG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AGG codon. go-plus.json arginine tRNA http://purl.obolibrary.org/obo/GO_0033448 GO:0033447 biolink:MolecularActivity AGA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AGA codon. go-plus.json arginine tRNA http://purl.obolibrary.org/obo/GO_0033447 CHEBI:83418 biolink:ChemicalSubstance S-(5-histidyl)cysteine sulfoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_83418 CHEBI:83417 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83417 chebi_ph7_3 CHEBI:83416 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83416 chebi_ph7_3 GO:0008489 biolink:MolecularActivity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base. MetaCyc:RXN-10764 go-plus.json LacCer synthase activity|UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity|lactosylceramide synthase activity http://purl.obolibrary.org/obo/GO_0008489 GO:0008488 biolink:MolecularActivity gamma-glutamyl carboxylase activity Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide. Reactome:R-HSA-163820|Reactome:R-HSA-159826|Reactome:R-HSA-163810|Reactome:R-HSA-159752|Reactome:R-HSA-9673231|Reactome:R-HSA-159795|Reactome:R-HSA-6807214|EC:4.1.1.90|RHEA:45140|Reactome:R-HSA-159803|Reactome:R-HSA-159819|Reactome:R-HSA-159761 go-plus.json http://purl.obolibrary.org/obo/GO_0008488 GO:0008487 biolink:MolecularActivity obsolete prenyl-dependent CAAX protease activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json prenyl-dependent CAAX protease activity http://purl.obolibrary.org/obo/GO_0008487 CHEBI:83414 biolink:ChemicalSubstance alkyl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83414 chebi_ph7_3 GO:0008486 biolink:MolecularActivity diphosphoinositol-polyphosphate diphosphatase activity Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate. MetaCyc:3.6.1.52-RXN|KEGG_REACTION:R05777|EC:3.6.1.52 go-plus.json DIPP activity|diphosphoinositol polyphosphate phosphohydrolase activity|diphospho-myo-inositol-polyphosphate diphosphohydrolase activity|diphosphoinositol-polyphosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0008486 GO:0008485 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008485 CHEBI:83412 biolink:ChemicalSubstance N(5)-acyl-L-ornithine ester(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83412 chebi_ph7_3 GO:0008484 biolink:MolecularActivity sulfuric ester hydrolase activity Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2. EC:3.1.6.-|MetaCyc:ARYLSULFAT-RXN go-plus.json sulphuric ester hydrolase activity|sulfatase activity http://purl.obolibrary.org/obo/GO_0008484 CHEBI:83411 biolink:ChemicalSubstance beta-D-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83411 chebi_ph7_3 GO:0008483 biolink:MolecularActivity transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid. Reactome:R-HSA-1237102|EC:2.6.1.- go-plus.json aminotransferase activity http://purl.obolibrary.org/obo/GO_0008483 CHEBI:83410 biolink:ChemicalSubstance alpha-amino acid ester(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83410 chebi_ph7_3 GO:0008493 biolink:MolecularActivity tetracycline transmembrane transporter activity Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). go-plus.json tetracycline transporter activity|tetracyclin transporter activity http://purl.obolibrary.org/obo/GO_0008493 GO:0008492 biolink:MolecularActivity obsolete cAMP generating peptide activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json cyclic AMP generating peptide activity|cAMP generating peptide activity http://purl.obolibrary.org/obo/GO_0008492 GO:0008491 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008491 GO:0008490 biolink:MolecularActivity arsenite secondary active transmembrane transporter activity Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json arsenite porter activity http://purl.obolibrary.org/obo/GO_0008490 PR:000009744 biolink:Protein low-density lipoprotein receptor A protein that is a translation product of the human LDLR gene or a 1:1 ortholog thereof. go-plus.json LDL receptor|LDLR http://purl.obolibrary.org/obo/PR_000009744 GO:0033446 biolink:MolecularActivity AGC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AGC codon. go-plus.json serine tRNA http://purl.obolibrary.org/obo/GO_0033446 GO:0033445 biolink:MolecularActivity AGU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AGU codon. go-plus.json AGT codon-amino acid adaptor activity|serine tRNA http://purl.obolibrary.org/obo/GO_0033445 GO:0033444 biolink:MolecularActivity AAG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AAG codon. go-plus.json lysine tRNA http://purl.obolibrary.org/obo/GO_0033444 GO:0033443 biolink:MolecularActivity AAA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AAA codon. go-plus.json lysine tRNA http://purl.obolibrary.org/obo/GO_0033443 CHEBI:138141 biolink:ChemicalSubstance 17alpha-hydroxy-C21-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138141 chebi_ph7_3 GO:0033442 biolink:MolecularActivity AAC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AAC codon. go-plus.json asparagine tRNA http://purl.obolibrary.org/obo/GO_0033442 CHEBI:138148 biolink:ChemicalSubstance 3'-end deoxyribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138148 chebi_ph7_3 GO:0033441 biolink:MolecularActivity AAU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AAU codon. go-plus.json AAT codon-amino acid adaptor activity|asparagine tRNA http://purl.obolibrary.org/obo/GO_0033441 CHEBI:138147 biolink:ChemicalSubstance 3'-end deoxyribonucleotide 3'-phosphate(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_138147 chebi_ph7_3 CHEBI:138146 biolink:ChemicalSubstance 13-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138146 GO:0033440 biolink:MolecularActivity ACG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an ACG codon. go-plus.json threonine tRNA http://purl.obolibrary.org/obo/GO_0033440 CHEBI:138145 biolink:ChemicalSubstance 1,2-di-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138145 chebi_ph7_3 GO:0033439 biolink:MolecularActivity ACA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an ACA codon. go-plus.json threonine tRNA http://purl.obolibrary.org/obo/GO_0033439 GO:0033438 biolink:MolecularActivity ACC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an ACC codon. go-plus.json threonine tRNA http://purl.obolibrary.org/obo/GO_0033438 GO:0033437 biolink:MolecularActivity ACU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an ACU codon. go-plus.json threonine tRNA|ACT codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033437 GO:0033436 biolink:MolecularActivity AUG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AUG codon. go-plus.json methionine tRNA|ATG codon-amino acid adaptor activity|initiator methionine tRNA http://purl.obolibrary.org/obo/GO_0033436 GO:0008499 biolink:MolecularActivity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP. Reactome:R-HSA-9603989|Reactome:R-HSA-914010 go-plus.json UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity|beta3Gal-Ts activity|beta-1,3-GalTase activity|UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0008499 GO:0008498 biolink:MolecularActivity obsolete phospholipid scrambling OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions. go-plus.json phospholipid scrambling http://purl.obolibrary.org/obo/GO_0008498 CHEBI:83425 biolink:ChemicalSubstance gamma-glutamyltyramine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83425 chebi_ph7_3 GO:0008497 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008497 GO:0008496 biolink:MolecularActivity mannan endo-1,6-alpha-mannosidase activity Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans. MetaCyc:3.2.1.101-RXN|EC:3.2.1.101|Reactome:R-HSA-6799581 go-plus.json mannan endo-1,6-beta-mannosidase activity|1,6-beta-D-mannan mannanohydrolase activity|endo-alpha-1->6-D-mannanase activity|exo-1,6-beta-mannanase activity|endo-alpha-D-mannosidase activity|1,6-alpha-D-mannan mannanohydrolase activity|endo-1,6-beta-mannanase activity http://purl.obolibrary.org/obo/GO_0008496 CHEBI:83423 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83423 chebi_ph7_3 GO:0008495 biolink:MolecularActivity protoheme IX farnesyltransferase activity Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate. EC:2.5.1.141|RHEA:28070|MetaCyc:HEMEOSYN-RXN|Reactome:R-HSA-2995330 go-plus.json haem O synthase activity|heme O synthase activity|protohaem IX farnesyltransferase activity|heme A:farnesyltransferase activity http://purl.obolibrary.org/obo/GO_0008495 CHEBI:83422 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83422 chebi_ph7_3 CHEBI:83421 biolink:ChemicalSubstance O-phospho-L-serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83421 chebi_ph7_3 GO:0008494 biolink:MolecularActivity translation activator activity Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0008494 CHEBI:83420 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83420 chebi_ph7_3 GO:0033435 biolink:MolecularActivity AUA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AUA codon. go-plus.json ATA codon-amino acid adaptor activity|isoleucine tRNA http://purl.obolibrary.org/obo/GO_0033435 GO:0033434 biolink:MolecularActivity AUC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AUC codon. go-plus.json ATC codon-amino acid adaptor activity|isoleucine tRNA http://purl.obolibrary.org/obo/GO_0033434 GO:0033433 biolink:MolecularActivity AUU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an AUU codon. go-plus.json ATT codon-amino acid adaptor activity|isoleucine tRNA http://purl.obolibrary.org/obo/GO_0033433 GO:0033432 biolink:MolecularActivity CGG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CGG codon. go-plus.json arginine tRNA http://purl.obolibrary.org/obo/GO_0033432 GO:0033431 biolink:MolecularActivity CGA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CGA codon. go-plus.json arginine tRNA http://purl.obolibrary.org/obo/GO_0033431 GO:0033430 biolink:MolecularActivity CGC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CGC codon. go-plus.json arginine tRNA http://purl.obolibrary.org/obo/GO_0033430 GO:0033429 biolink:MolecularActivity CGU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CGU codon. go-plus.json CGT codon-amino acid adaptor activity|arginine tRNA http://purl.obolibrary.org/obo/GO_0033429 GO:0033428 biolink:MolecularActivity CAG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CAG codon. go-plus.json glutamine tRNA http://purl.obolibrary.org/obo/GO_0033428 GO:0033427 biolink:MolecularActivity CAA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CAA codon. go-plus.json glutamine tRNA http://purl.obolibrary.org/obo/GO_0033427 GO:0033426 biolink:MolecularActivity CAC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CAC codon. go-plus.json histidine tRNA http://purl.obolibrary.org/obo/GO_0033426 GO:0008469 biolink:MolecularActivity histone-arginine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine. Reactome:R-HSA-5205861|Reactome:R-HSA-5661117|Reactome:R-HSA-8936584|Reactome:R-HSA-5205799|Reactome:R-HSA-5216234|Reactome:R-HSA-8937022|Reactome:R-HSA-8937113|Reactome:R-HSA-8936608 go-plus.json protein methylase I activity|histone protein methylase I|S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity|histone methyltransferase activity|histone protein methylase activity|S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity|nuclear protein (histone) N-methyltransferase activity|histone-arginine N-methylase activity http://purl.obolibrary.org/obo/GO_0008469 GO:0033425 biolink:MolecularActivity CAU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CAU codon. go-plus.json CAT codon-amino acid adaptor activity|histidine tRNA http://purl.obolibrary.org/obo/GO_0033425 GO:0008468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008468 CHEBI:83439 biolink:ChemicalSubstance iminoarginine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83439 chebi_ph7_3 GO:0008467 biolink:MolecularActivity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S. MetaCyc:2.8.2.23-RXN|EC:2.8.2.23|Reactome:R-HSA-2076383|Reactome:R-HSA-2076611 go-plus.json heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase activity|3-OST-1 activity|heparin-glucosamine 3-O-sulfotransferase activity|heparin-glucosamine 3-O-sulphotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase|isoform/isozyme 1 (3-OST-1, HS3ST1) http://purl.obolibrary.org/obo/GO_0008467 GO:0008466 biolink:MolecularActivity glycogenin glucosyltransferase activity Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin. EC:2.4.1.186|Reactome:R-HSA-3814838|MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN|Reactome:R-HSA-3322019|Reactome:R-HSA-3322025|Reactome:R-HSA-3322003|Reactome:R-HSA-3322014|RHEA:23360 go-plus.json priming glucosyltransferase activity|1,4alpha-glucan-protein synthase (UDP-forming) activity|alpha-1,4-glucan-protein synthase (UDP-forming) activity|UDP-glucose:glycogenin glucosyltransferase activity|UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity|glycogenin activity http://purl.obolibrary.org/obo/GO_0008466 GO:0008465 biolink:MolecularActivity glycerate dehydrogenase activity Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+. EC:1.1.1.29|RHEA:17905|MetaCyc:GLYCERATE-DEHYDROGENASE-RXN go-plus.json hydroxypyruvate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008465 CHEBI:83436 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83436 chebi_ph7_3 GO:0008464 biolink:MolecularActivity obsolete gamma-glutamyl hydrolase activity OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid. go-plus.json poly(glutamic acid) hydrolase II|folic acid conjugase activity|conjugase activity|poly(gamma-glutamic acid) endohydrolase activity|pteroyl-poly-alpha-glutamate hydrolase activity|lysosomal gamma-glutamyl carboxypeptidase activity|gamma-Glu-X carboxypeptidase activity|folate conjugase activity|gamma-glutamyl hydrolase activity|carboxypeptidase G activity|polyglutamate hydrolase activity|pteroyl-poly-gamma-glutamate hydrolase activity|pteroylpoly-gamma-glutamyl hydrolase activity http://purl.obolibrary.org/obo/GO_0008464 CHEBI:83435 biolink:ChemicalSubstance 3,6-anhydro-L-galactonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83435 chebi_ph7_3 GO:0008463 biolink:MolecularActivity formylmethionine deformylase activity Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate. MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN|KEGG_REACTION:R00653|EC:3.5.1.31|RHEA:17781 go-plus.json N-formyl-L-methionine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0008463 CHEBI:83434 biolink:ChemicalSubstance 2-hydroxy-5-methyl-1-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83434 GO:0008462 biolink:MolecularActivity obsolete endopeptidase Clp activity OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs). go-plus.json endopeptidase Ti activity|endopeptidase Clp activity|caseinolytic protease activity|Clp protease|protease Ti activity|ATP-dependent Clp protease|ClpP http://purl.obolibrary.org/obo/GO_0008462 CHEBI:83433 biolink:ChemicalSubstance 3,6-anhydro-alpha-L-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_83433 chebi_ph7_3 GO:0008461 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008461 GO:0008471 biolink:MolecularActivity obsolete laccase activity OBSOLETE. Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O. go-plus.json p-diphenol oxidase activity|urishiol oxidase activity|urushiol oxidase activity|benzenediol:oxygen oxidoreductase activity|laccase activity http://purl.obolibrary.org/obo/GO_0008471 CHEBI:83431 biolink:ChemicalSubstance [5-(ammoniomethyl)-3-furyl]methyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83431 chebi_ph7_3 GO:0008470 biolink:MolecularActivity isovaleryl-CoA dehydrogenase activity Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF. EC:1.3.8.4|RHEA:12276|Reactome:R-HSA-70745|MetaCyc:ISOVALERYL-COA-FAD-RXN go-plus.json isovaleryl-coenzyme A dehydrogenase activity|isovaleroyl-coenzyme A dehydrogenase activity|3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity|3-methylbutanoyl-CoA:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008470 GO:0033424 biolink:MolecularActivity CCG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CCG codon. go-plus.json proline tRNA http://purl.obolibrary.org/obo/GO_0033424 CHEBI:138121 biolink:ChemicalSubstance dermatan 4',6'-disulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138121 chebi_ph7_3 GO:0033423 biolink:MolecularActivity CCA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CCA codon. go-plus.json proline tRNA http://purl.obolibrary.org/obo/GO_0033423 GO:0033422 biolink:MolecularActivity CCC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CCC codon. go-plus.json proline tRNA http://purl.obolibrary.org/obo/GO_0033422 GO:0033421 biolink:MolecularActivity CCU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CCU codon. go-plus.json CCT codon-amino acid adaptor activity|proline tRNA http://purl.obolibrary.org/obo/GO_0033421 GO:0033420 biolink:MolecularActivity CUG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUG codon. go-plus.json leucine tRNA|CTG codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033420 GO:0033419 biolink:MolecularActivity CUA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUA codon. go-plus.json CTA codon-amino acid adaptor activity|leucine tRNA http://purl.obolibrary.org/obo/GO_0033419 GO:0033418 biolink:MolecularActivity CUC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUC codon. go-plus.json leucine tRNA|CTC codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033418 GO:0033417 biolink:MolecularActivity CUU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUU codon. go-plus.json leucine tRNA|CTT codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033417 CHEBI:138140 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138140 chebi_ph7_3 GO:0033416 biolink:MolecularActivity UGG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UGG codon. go-plus.json tryptophan tRNA|TGG codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033416 GO:0033415 biolink:MolecularActivity UGA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UGA codon. go-plus.json TGA codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033415 GO:0033414 biolink:MolecularActivity UGC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UGC codon. go-plus.json TGC codon-amino acid adaptor activity|cysteine tRNA http://purl.obolibrary.org/obo/GO_0033414 GO:0008479 biolink:MolecularActivity queuine tRNA-ribosyltransferase activity Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine. Reactome:R-HSA-6782443|RHEA:16633|MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.29 go-plus.json transfer ribonucleate glycosyltransferase activity|guanine, queuine-tRNA transglycosylase activity|tRNA-guanine transglycosylase activity|Q-insertase activity|queuine transfer ribonucleate ribosyltransferase activity|[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity|tRNA guanine transglycosidase activity|guanine insertion enzyme activity|tRNA transglycosylase activity http://purl.obolibrary.org/obo/GO_0008479 GO:0008478 biolink:MolecularActivity pyridoxal kinase activity Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate. MetaCyc:PYRIDOXKIN-RXN|EC:2.7.1.35|RHEA:10224|Reactome:R-HSA-964962|Reactome:R-HSA-964970|Reactome:R-HSA-964958 go-plus.json vitamin B6 kinase activity|ATP:pyridoxal 5'-phosphotransferase activity|pyridoxine kinase activity|pyridoxal 5-phosphate-kinase activity|pyridoxal phosphokinase activity|pyridoxal kinase (phosphorylating)|pyridoxamine kinase activity|vitamin B(6) kinase activity http://purl.obolibrary.org/obo/GO_0008478 GO:0008477 biolink:MolecularActivity purine nucleosidase activity Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose. RHEA:23344|MetaCyc:PURINE-NUCLEOSIDASE-RXN|EC:3.2.2.1 go-plus.json inosine-adenosine-guanosine preferring nucleoside hydrolase activity|ribonucleoside hydrolase activity|nucleoside hydrolase activity|purine ribonucleosidase activity|purine nucleoside hydrolase activity|IAG-NH activity|purine beta-ribosidase activity|purine-specific nucleoside N-ribohydrolase activity|nucleosidase g activity|purine nucleosidase reaction|purine-nucleoside ribohydrolase activity|N-D-ribosylpurine ribohydrolase activity|N-ribosyl purine ribohydrolase activity|nucleosidase activity|IAG-nucleoside hydrolase activity http://purl.obolibrary.org/obo/GO_0008477 GO:0008476 biolink:MolecularActivity protein-tyrosine sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate. RHEA:16801|EC:2.8.2.20|Reactome:R-HSA-9668023|Reactome:R-HSA-8954262|Reactome:R-HSA-9668148|MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN go-plus.json tyrosylprotein sulfotransferase activity|protein-tyrosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0008476 goslim_chembl GO:0008475 biolink:MolecularActivity procollagen-lysine 5-dioxygenase activity Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2. RHEA:16569|EC:1.14.11.4|MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN|Reactome:R-HSA-1981104 go-plus.json protocollagen lysyl hydroxylase activity|procollagen-lysine,2-oxoglutarate 5-dioxygenase activity|collagen lysine hydroxylase activity|lysyl hydroxylase activity|lysylprotocollagen dioxygenase activity|lysine hydroxylase activity|lysine-2-oxoglutarate dioxygenase activity|lysine,2-oxoglutarate 5-dioxygenase activity|procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)|protocollagen lysine dioxygenase activity|protocollagen lysine hydroxylase activity http://purl.obolibrary.org/obo/GO_0008475 GO:0008474 biolink:MolecularActivity palmitoyl-(protein) hydrolase activity Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein. Reactome:R-HSA-203613|Reactome:R-HSA-9647994|RHEA:19233|MetaCyc:3.1.2.22-RXN|Reactome:R-HSA-8933328|Reactome:R-HSA-5690517|EC:3.1.2.22 go-plus.json palmitoyl-protein thiolesterase activity|palmitoyl-protein hydrolase activity|palmitoyl-[protein] hydrolase|palmitoyl-protein thioesterase activity http://purl.obolibrary.org/obo/GO_0008474 goslim_chembl NCBITaxon:214909 biolink:OrganismalEntity Byttnerioideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_214909 GO:0008473 biolink:MolecularActivity ornithine cyclodeaminase activity Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+). RHEA:24368|KEGG_REACTION:R00671|MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN|EC:4.3.1.12 go-plus.json ornithine cyclase activity|L-ornithine ammonia-lyase (cyclizing; L-proline-forming)|OCD activity|L-ornithine ammonia-lyase (cyclizing)|ornithine cyclase (deaminating) activity http://purl.obolibrary.org/obo/GO_0008473 CHEBI:83444 biolink:ChemicalSubstance 4-(5-O-phospho-beta-D-ribofuranosyl)phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_83444 GO:0008472 biolink:MolecularActivity obsolete metallocarboxypeptidase D activity OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid. go-plus.json carboxypeptidase D (cattle, human, mouse, rat)|metallocarboxypeptidase D activity|gp180 (duck) http://purl.obolibrary.org/obo/GO_0008472 NCBITaxon:214907 biolink:OrganismalEntity Malvoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_214907 GO:0008482 biolink:MolecularActivity sulfite oxidase activity Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate. MetaCyc:PWY-5326|KEGG_REACTION:R00533|RHEA:24600|Reactome:R-HSA-1614544|MetaCyc:SULFITE-OXIDASE-RXN|EC:1.8.3.1 go-plus.json sulphite oxidase activity|sulfite:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008482 GO:0008481 biolink:MolecularActivity sphinganine kinase activity Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate. RHEA:15465|EC:2.7.1.91|MetaCyc:SPHINGANINE-KINASE-RXN|Reactome:R-HSA-428214 go-plus.json sphingosine kinase (phosphorylating)|dihydrosphingosine kinase activity|ATP:sphinganine 1-phosphotransferase activity|sphingosine kinase activity|dihydrosphingosine kinase (phosphorylating) http://purl.obolibrary.org/obo/GO_0008481 CHEBI:83441 biolink:ChemicalSubstance O-[S-(3R)-hydroxyicosanoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83441 chebi_ph7_3 GO:0008480 biolink:MolecularActivity sarcosine dehydrogenase activity Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein. Reactome:R-HSA-6797913|KEGG_REACTION:R00611|MetaCyc:SARCOSINE-DEHYDROGENASE-RXN|EC:1.5.8.3|RHEA:19793 go-plus.json monomethylglycine dehydrogenase activity|sarcosine:acceptor oxidoreductase (demethylating)|sarcosine:(acceptor) oxidoreductase (demethylating)|sarcosine N-demethylase activity http://purl.obolibrary.org/obo/GO_0008480 CHEBI:138139 biolink:ChemicalSubstance 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_138139 chebi_ph7_3 CHEBI:83440 biolink:ChemicalSubstance O-(S-3-oxoicosanoylpantetheine-4'-phosphoryl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83440 chebi_ph7_3 CHEBI:138138 biolink:ChemicalSubstance epoxy(hydroxy)icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138138 GO:0033413 biolink:MolecularActivity UGU codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UGU codon. go-plus.json TGT codon-amino acid adaptor activity|cysteine tRNA http://purl.obolibrary.org/obo/GO_0033413 GO:0033412 biolink:MolecularActivity UAG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UAG codon. go-plus.json TAG codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033412 GO:0033411 biolink:MolecularActivity UAA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UAA codon. go-plus.json TAA codon-amino acid adaptor activity http://purl.obolibrary.org/obo/GO_0033411 CHEBI:138131 biolink:ChemicalSubstance Delta(5),Delta(7)-sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138131 chebi_ph7_3 CHEBI:138130 biolink:ChemicalSubstance Delta(7)-sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_138130 chebi_ph7_3 GO:0033410 biolink:MolecularActivity UAC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UAC codon. go-plus.json TAC codon-amino acid adaptor activity|tyrosine tRNA http://purl.obolibrary.org/obo/GO_0033410 CHEBI:138135 biolink:ChemicalSubstance (13S)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_138135 UBERON:3000961 biolink:AnatomicalEntity external integument structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. go-plus.json http://purl.obolibrary.org/obo/UBERON_3000961 UBERON:3000981 biolink:AnatomicalEntity limb external integument structure Dermal, epidermal, glandular and pigment structures of the limb integument. go-plus.json http://purl.obolibrary.org/obo/UBERON_3000981 UBERON:3000977 biolink:AnatomicalEntity body external integument structure Dermal, epidermal, glandular and pigment structures of the body integument. go-plus.json http://purl.obolibrary.org/obo/UBERON_3000977 UBERON:3000972 biolink:AnatomicalEntity head external integument structure Dermal, epidermal, glandular and pigment structures of the external head integument. go-plus.json http://purl.obolibrary.org/obo/UBERON_3000972 CHEBI:10417 biolink:ChemicalSubstance beta-eudesmol go-plus.json http://purl.obolibrary.org/obo/CHEBI_10417 chebi_ph7_3 CHEBI:10415 biolink:ChemicalSubstance beta-endorphin go-plus.json http://purl.obolibrary.org/obo/CHEBI_10415 CHEBI:10418 biolink:ChemicalSubstance trans-beta-farnesene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10418 chebi_ph7_3 UBERON:0001095 biolink:AnatomicalEntity caudal vertebra Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx). go-plus.json caudal vertebrae|caudal vertebral bone|caudal vertebra|caudal vertebral bone element|coccygea|fused tail vertebra|coccygeal segment|tail vertebra|coccygeal vertebra http://purl.obolibrary.org/obo/UBERON_0001095 UBERON:0001096 biolink:AnatomicalEntity wall of esophagus An anatomical wall that is part of a esophagus [Automatically generated definition]. go-plus.json esophagus anatomical wall|gullet anatomical wall|wall of oesophagus|anatomical wall of oesophagus|oesophagus wall|esophageal wall|oesophagus anatomical wall|wall of gullet|esophagus wall|gullet wall|anatomical wall of esophagus|anatomical wall of gullet http://purl.obolibrary.org/obo/UBERON_0001096 UBERON:0001091 biolink:AnatomicalEntity calcareous tooth Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. go-plus.json dentine containing tooth|vertebrate tooth|dental element|tooth http://purl.obolibrary.org/obo/UBERON_0001091 UBERON:0001090 biolink:AnatomicalEntity synovial fluid Joint fluid is a transudate of plasma that is actively secreted by synovial cells. go-plus.json joint fluid http://purl.obolibrary.org/obo/UBERON_0001090 UBERON:0001093 biolink:AnatomicalEntity vertebral bone 2 The second vertebral bone in the vertebral column. go-plus.json axis|axis vertebra|cervical axis|C2 vertebra|axis (CII)|vertebra 2|second cervical vertebra|cervical vertebra 2|C2|axis [C II] http://purl.obolibrary.org/obo/UBERON_0001093 UBERON:0001092 biolink:AnatomicalEntity vertebral bone 1 The first vertebral bone in the vertebral column. go-plus.json first cervical vertebra|atlas [C I]|cervical atlas|atlas vertebra|atlas (CI)|C1 vertebra|vertebra 1|atlas|C1|cervical vertebra 1 http://purl.obolibrary.org/obo/UBERON_0001092 UBERON:3000982 biolink:AnatomicalEntity tail external integument structure Dermal, epidermal, glandular and pigment structures of the tail integument. go-plus.json http://purl.obolibrary.org/obo/UBERON_3000982 UBERON:0001084 biolink:AnatomicalEntity skin of head A zone of skin that is part of a head [Automatically generated definition]. go-plus.json head zone of skin|adult head zone of skin|zone of skin of adult head|head skin|zone of skin of head http://purl.obolibrary.org/obo/UBERON_0001084 UBERON:0001083 biolink:AnatomicalEntity myocardium of ventricle Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer. go-plus.json ventricular myocardium|ventricle cardiac muscle|ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 UBERON:0001085 biolink:AnatomicalEntity skin of trunk A zone of skin that is part of a trunk [Automatically generated definition]. go-plus.json trunk skin|torso zone of skin|trunk zone of skin|zone of skin of trunk|zone of skin of torso http://purl.obolibrary.org/obo/UBERON_0001085 UBERON:0001082 biolink:AnatomicalEntity epicardium of ventricle An epicardial layer that lines a cardiac ventricle go-plus.json ventricular epicardium|cardiac ventricle epicardium http://purl.obolibrary.org/obo/UBERON_0001082 UBERON:0001081 biolink:AnatomicalEntity endocardium of ventricle Endocardium that is part of the cardiac ventricle. go-plus.json endocardium of ventricle of heart|heart ventricle endocardium|endocardium of heart ventricle|ventricle endocardium|ventricle of heart endocardium|cardiac ventricle endocardium|endocardium of cardiac ventricle|endocardium of lower chamber of heart|ventricle endocardial tissue|ventricular endocardium|lower chamber of heart endocardium http://purl.obolibrary.org/obo/UBERON_0001081 UBERON:0001088 biolink:AnatomicalEntity urine Excretion that is the output of a kidney go-plus.json http://purl.obolibrary.org/obo/UBERON_0001088 UBERON:0001087 biolink:AnatomicalEntity pleural fluid Transudate contained in the pleural cavity. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001087 UBERON:0001089 biolink:AnatomicalEntity sweat Secretion produced by a sweat gland. go-plus.json skin exudate http://purl.obolibrary.org/obo/UBERON_0001089 CHEBI:2651 biolink:ChemicalSubstance alpha-aminoacyl-tRNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_2651 GO:0033394 biolink:BiologicalProcess beta-alanine biosynthetic process via 1,3 diaminopropane The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane. MetaCyc:PWY-3981 go-plus.json beta-alanine formation via 1,3 diaminopropane|beta-alanine synthesis via 1,3 diaminopropane|beta-alanine biosynthesis via 1,3 diaminopropane|beta-alanine anabolism via 1,3 diaminopropane http://purl.obolibrary.org/obo/GO_0033394 GO:0033393 biolink:BiologicalProcess homogalacturonan catabolic process The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. MetaCyc:PWY-1081 go-plus.json homogalacturonan degradation|homogalacturonan breakdown|homogalacturonan catabolism http://purl.obolibrary.org/obo/GO_0033393 GO:0033392 biolink:MolecularActivity obsolete actin homodimerization activity OBSOLETE. Binding to an identical actin monomer to form a homodimer. go-plus.json actin homodimerization activity|actin dimerization activity|actin polymerizing activity http://purl.obolibrary.org/obo/GO_0033392 GO:0033391 biolink:CellularComponent chromatoid body A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182). go-plus.json http://purl.obolibrary.org/obo/GO_0033391 GO:0033390 biolink:BiologicalProcess putrescine biosynthetic process from arginine via N-carbamoylputrescine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps. go-plus.json putrescine anabolism from arginine via N-carbamoylputrescine|putrescine synthesis from arginine via N-carbamoylputrescine|putrescine formation from arginine via N-carbamoylputrescine|putrescine biosynthesis from arginine via N-carbamoylputrescine http://purl.obolibrary.org/obo/GO_0033390 GO:0033399 biolink:BiologicalProcess cis-zeatin metabolic process The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. go-plus.json cis-zeatin metabolism http://purl.obolibrary.org/obo/GO_0033399 GO:0033398 biolink:BiologicalProcess zeatin biosynthetic process The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. go-plus.json zeatin anabolism|zeatin synthesis|zeatin formation|zeatin biosynthesis http://purl.obolibrary.org/obo/GO_0033398 GO:0033397 biolink:BiologicalProcess zeatin metabolic process The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. go-plus.json zeatin metabolism http://purl.obolibrary.org/obo/GO_0033397 GO:0033396 biolink:BiologicalProcess beta-alanine biosynthetic process via 3-ureidopropionate The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate. MetaCyc:PWY-3982 go-plus.json beta-alanine formation via 3-ureidopropionate|beta-alanine synthesis via 3-ureidopropionate|beta-alanine anabolism via 3-ureidopropionate http://purl.obolibrary.org/obo/GO_0033396 GO:0033395 biolink:BiologicalProcess beta-alanine biosynthetic process via 3-hydroxypropionate The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate. MetaCyc:PWY-3941 go-plus.json beta-alanine anabolism via 3-hydroxypropionate|beta-alanine biosynthesis via 3-hydroxypropionate|beta-alanine synthesis via 3-hydroxypropionate|beta-alanine formation via 3-hydroxypropionate http://purl.obolibrary.org/obo/GO_0033395 CHEBI:2639 biolink:ChemicalSubstance amiloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_2639 chebi_ph7_3 GO:0033383 biolink:BiologicalProcess geranyl diphosphate metabolic process The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes. go-plus.json geranyldiphosphate metabolic process|geranyl diphosphate metabolism http://purl.obolibrary.org/obo/GO_0033383 GO:0033382 biolink:BiologicalProcess maintenance of granzyme B location in T cell secretory granule A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere. go-plus.json maintenance of granzyme B localization in T-cell secretory granule|maintenance of granzyme B localization in T-lymphocyte secretory granule|maintenance of granzyme B localization in T cell secretory granule|maintenance of granzyme B localization in T lymphocyte secretory granule http://purl.obolibrary.org/obo/GO_0033382 GO:0033381 biolink:BiologicalProcess establishment of granzyme B localization to T cell secretory granule The directed movement of the protease granzyme B to a location within a secretory granule in a T cell. go-plus.json establishment of granzyme B localization in T lymphocyte secretory granule|T-lymphocyte secretory granule storage of granzyme B|establishment of granzyme B localization in T-cell secretory granule|establishment of granzyme B localization in T-lymphocyte secretory granule|establishment of granzyme B localisation in T cell secretory granule|establishment of granzyme B localization in T cell secretory granule http://purl.obolibrary.org/obo/GO_0033381 GO:0033380 biolink:BiologicalProcess granzyme B localization to T cell secretory granule Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell. go-plus.json granzyme B localization in T lymphocyte secretory granule|granzyme B localization in T-cell secretory granule|granzyme B localization in T-lymphocyte secretory granule|granzyme B localisation in T cell secretory granule|granzyme B localization in T cell secretory granule http://purl.obolibrary.org/obo/GO_0033380 CHEBI:2634 biolink:ChemicalSubstance amidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_2634 GO:0033389 biolink:BiologicalProcess putrescine biosynthetic process from arginine, using agmatinase The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step. go-plus.json putrescine anabolism from arginine, using agmatinase|putrescine synthesis from arginine, using agmatinase|putrescine formation from arginine, using agmatinase|putrescine biosynthesis from arginine, using agmatinase http://purl.obolibrary.org/obo/GO_0033389 GO:0033388 biolink:BiologicalProcess putrescine biosynthetic process from arginine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine. go-plus.json putrescine anabolism from arginine|putrescine synthesis from arginine|putrescine formation from arginine|putrescine biosynthesis from arginine http://purl.obolibrary.org/obo/GO_0033388 GO:0033387 biolink:BiologicalProcess putrescine biosynthetic process from ornithine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine. go-plus.json putrescine biosynthesis from ornithine|putrescine formation from ornithine|putrescine synthesis from ornithine|putrescine anabolism from ornithine http://purl.obolibrary.org/obo/GO_0033387 GO:0033386 biolink:BiologicalProcess geranylgeranyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate. MetaCyc:PWY-5121|MetaCyc:PWY-5120 go-plus.json geranylgeranyl diphosphate synthesis|geranylgeranyl diphosphate formation|geranylgeranyl diphosphate biosynthesis|geranylgeranyl diphosphate anabolism http://purl.obolibrary.org/obo/GO_0033386 GO:0033385 biolink:BiologicalProcess geranylgeranyl diphosphate metabolic process The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins. go-plus.json geranylgeranyldiphosphate metabolic process|geranylgeranyl diphosphate metabolism http://purl.obolibrary.org/obo/GO_0033385 GO:0033384 biolink:BiologicalProcess geranyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of geranyl diphosphate. MetaCyc:PWY-5122 go-plus.json geranyldiphosphate biosynthetic process|geranyl diphosphate anabolism|geranyl diphosphate synthesis|geranyl diphosphate biosynthesis|geranyl diphosphate formation http://purl.obolibrary.org/obo/GO_0033384 GO:0033372 biolink:BiologicalProcess establishment of protease localization to mast cell secretory granule The directed movement of a protease to a location within a secretory granule in a mast cell. go-plus.json establishment of protease localization in mast cell secretory granule|establishment of protease localisation in mast cell secretory granule http://purl.obolibrary.org/obo/GO_0033372 GO:0033371 biolink:BiologicalProcess T cell secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. go-plus.json T-cell secretory granule organization|T cell secretory granule organization and biogenesis|T lymphocyte secretory granule organization|T cell secretory granule organisation|T-lymphocyte secretory granule maturation|T-lymphocyte secretory granule organization http://purl.obolibrary.org/obo/GO_0033371 GO:0033370 biolink:BiologicalProcess maintenance of protein location in mast cell secretory granule A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere. go-plus.json mast cell protein retention|maintenance of protein localization in mast cell secretory granule http://purl.obolibrary.org/obo/GO_0033370 GO:0033379 biolink:BiologicalProcess maintenance of protease location in T cell secretory granule A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere. go-plus.json maintenance of protease localization in T-cell secretory granule|maintenance of protease localization in T-lymphocyte secretory granule|maintenance of protease localization in T cell secretory granule|maintenance of protease localization in T lymphocyte secretory granule http://purl.obolibrary.org/obo/GO_0033379 GO:0033378 biolink:BiologicalProcess establishment of protease localization to T cell secretory granule The directed movement of a protease to a location within a secretory granule in a T cell. go-plus.json establishment of protease localization in T-cell secretory granule|establishment of protease localization in T-lymphocyte secretory granule|establishment of protease localisation in T cell secretory granule|establishment of protease localization in T cell secretory granule|establishment of protease localization in T lymphocyte secretory granule http://purl.obolibrary.org/obo/GO_0033378 GO:0033377 biolink:BiologicalProcess maintenance of protein location in T cell secretory granule A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere. go-plus.json maintenance of protein localization in T-lymphocyte secretory granule|maintenance of protein localization in T cell secretory granule|maintenance of protein localization in T lymphocyte secretory granule|maintenance of protein localization in T-cell secretory granule http://purl.obolibrary.org/obo/GO_0033377 GO:0033376 biolink:BiologicalProcess establishment of protein localization to T cell secretory granule The directed movement of a protein to a location within a secretory granule in a T cell. go-plus.json establishment of protein localisation in T cell secretory granule|establishment of protein localization in T cell secretory granule|establishment of protein localization in T lymphocyte secretory granule|establishment of protein localization in T-cell secretory granule|establishment of protein localization in T-lymphocyte secretory granule http://purl.obolibrary.org/obo/GO_0033376 GO:0033375 biolink:BiologicalProcess protease localization to T cell secretory granule Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell. go-plus.json protease localization in T-cell secretory granule|protease localization in T-lymphocyte secretory granule|protease localisation in T cell secretory granule|protease localization in T cell secretory granule|protease localization in T lymphocyte secretory granule http://purl.obolibrary.org/obo/GO_0033375 GO:0033374 biolink:BiologicalProcess protein localization to T cell secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell. go-plus.json protein localisation in T cell secretory granule|protein localization in T cell secretory granule|protein localization in T lymphocyte secretory granule|protein localization in T-cell secretory granule|protein localization in T-lymphocyte secretory granule http://purl.obolibrary.org/obo/GO_0033374 GO:0033373 biolink:BiologicalProcess maintenance of protease location in mast cell secretory granule A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere. go-plus.json maintenance of protease localization in mast cell secretory granule|mast cell protease retention http://purl.obolibrary.org/obo/GO_0033373 PO:0020094 biolink:OntologyClass plant egg cell A gamete (PO:0025006) produced by an archegonium (PO:0025126) or an embryo sac (PO:0025074). go-plus.json egg cell (broad)|植物卵細胞 (Japanese, exact)|oocélula (Spanish, exact)|female gamete (exact)|megagamete (exact)|non-mobile gamete (broad) http://purl.obolibrary.org/obo/PO_0020094 PO:0020093 biolink:OntologyClass antipodal cell Cell, commonly three in number as in the eight-nucleate embryo sac, located at the other end of the embryo sac from the egg cell. go-plus.json célula antipodal (Spanish, exact)|反足細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020093 PO:0020096 biolink:OntologyClass egg apparatus A cardinal organ part that has as parts an egg cell and two synergids and is located at the micropylar end of the embryo sac. go-plus.json 卵装置 (Japanese, exact)|aparato de la oocélula (Spanish, exact) http://purl.obolibrary.org/obo/PO_0020096 PO:0020090 biolink:OntologyClass embryo sac central cell An embryo sac cell (PO:0025026) that is largest cell in a mature embryo sac (PO:0025074). go-plus.json 中央細胞 (Japanese, exact)|célula central (Spanish, exact) http://purl.obolibrary.org/obo/PO_0020090 CL:3000002 biolink:Cell sympathetic noradrenergic neuron Sympathetic noradrenergic neuron. go-plus.json http://purl.obolibrary.org/obo/CL_3000002 CHEBI:58419 biolink:ChemicalSubstance 4-hydroxy-L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58419 chebi_ph7_3 CHEBI:58418 biolink:ChemicalSubstance ditrans,polycis-decaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58418 chebi_ph7_3 UBERON:0001037 biolink:AnatomicalEntity strand of hair A filament, mostly protein, that grows from follicles found in the dermis[WP]. go-plus.json coat/ hair|hair|quill|fur|coat hair|whisker|setulae|vibrissa|microchaeta http://purl.obolibrary.org/obo/UBERON_0001037 NCBITaxon:70447 biolink:OrganismalEntity Ostreococcus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_70447 CHEBI:58416 biolink:ChemicalSubstance chlorophyll a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58416 chebi_ph7_3 CHEBI:58415 biolink:ChemicalSubstance deacetoxycephalosporin C(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58415 chebi_ph7_3 NCBITaxon:70448 biolink:OrganismalEntity Ostreococcus tauri go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_70448 CHEBI:58414 biolink:ChemicalSubstance 1D-myo-inositol 1,3,4-trisphosphate(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58414 chebi_ph7_3 CL:3000003 biolink:Cell sympathetic cholinergic neuron Sympathetic cholinergic neuron. go-plus.json http://purl.obolibrary.org/obo/CL_3000003 UBERON:0001033 biolink:AnatomicalEntity gustatory system The sensory system for the sense of taste. go-plus.json gustatory organ system|taste system http://purl.obolibrary.org/obo/UBERON_0001033 CHEBI:58413 biolink:ChemicalSubstance (R)-6-hydroxynicotinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58413 chebi_ph7_3 UBERON:0001032 biolink:AnatomicalEntity sensory system Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. go-plus.json sensory subsystem|sense organ subsystem|organa sensuum|sensory systems|organa sensuum|sensory organ system|set of sense organs|sense organs set|sense organs http://purl.obolibrary.org/obo/UBERON_0001032 CHEBI:58412 biolink:ChemicalSubstance syringetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58412 chebi_ph7_3 CHEBI:58411 biolink:ChemicalSubstance CoM-S-S-CoB(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58411 chebi_ph7_3 CHEBI:58410 biolink:ChemicalSubstance 2-amino-5-oxocyclohex-1-enecarbonyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58410 chebi_ph7_3 UBERON:0001019 biolink:AnatomicalEntity nerve fasciculus A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, as of muscle or nerve (American Heritage Dictionary 4th ed). go-plus.json fascicle|nerve fasciculus|nerve fiber tract|neural fasciculus|fasciculus|nerve bundle http://purl.obolibrary.org/obo/UBERON_0001019 UBERON:0001018 biolink:AnatomicalEntity axon tract A group of axons linking two or more neuropils and having a common origin, termination[FBbt]. go-plus.json tract of neuraxis|tract|neuraxis tract|nerve tract|nerve tract|axonal tract http://purl.obolibrary.org/obo/UBERON_0001018 CHEBI:58409 biolink:ChemicalSubstance alpha-D-mannose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58409 chebi_ph7_3 CHEBI:58408 biolink:ChemicalSubstance penicillin N(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58408 chebi_ph7_3 CHEBI:58407 biolink:ChemicalSubstance isoscoparin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58407 chebi_ph7_3 UBERON:0001020 biolink:AnatomicalEntity nervous system commissure Axon tract that crosses the midline of the central nervous system[NIF, modified]. In the context of Drosophila refers to a broad band of axons connecting equivalent neuropils each side of the brain[FBbt]. go-plus.json white matter commissure|neuraxis commissure|commissure of neuraxis|commissure http://purl.obolibrary.org/obo/UBERON_0001020 CHEBI:58406 biolink:ChemicalSubstance 4-amino-4-deoxychorismate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58406 chebi_ph7_3 CHEBI:58405 biolink:ChemicalSubstance ditrans,polycis-undecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58405 chebi_ph7_3 CHEBI:58404 biolink:ChemicalSubstance (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58404 chebi_ph7_3 UBERON:0001027 biolink:AnatomicalEntity sensory nerve A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. go-plus.json afferent nerve|nervus sensorius http://purl.obolibrary.org/obo/UBERON_0001027 CHEBI:58403 biolink:ChemicalSubstance 3,5,3'-triiodothyropyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58403 chebi_ph7_3 CHEBI:58402 biolink:ChemicalSubstance 5-oxo-L-prolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58402 chebi_ph7_3 CHEBI:58401 biolink:ChemicalSubstance 1D-myo-inositol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58401 chebi_ph7_3 UBERON:0001021 biolink:AnatomicalEntity nerve An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. go-plus.json neural subtree|nerves|peripheral nerve http://purl.obolibrary.org/obo/UBERON_0001021 CHEBI:58400 biolink:ChemicalSubstance 2-oxophytanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58400 chebi_ph7_3 CHEBI:34450 biolink:ChemicalSubstance 5,6-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_34450 UBERON:0001008 biolink:AnatomicalEntity renal system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products.. go-plus.json systema urinarium|urinary tract|systema urinaria|renal/urinary system|excretory system|renal system|urinary system|renal or urinary system http://purl.obolibrary.org/obo/UBERON_0001008 UBERON:0001007 biolink:AnatomicalEntity digestive system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. go-plus.json gut|alimentary system|alimentary tract|gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0001007 UBERON:0001009 biolink:AnatomicalEntity circulatory system organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. go-plus.json systema cardiovasculare http://purl.obolibrary.org/obo/UBERON_0001009 OBO:GOCHE_50249 biolink:OntologyClass substance with anticoagulant role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50249 3_STAR UBERON:2001471 biolink:AnatomicalEntity posterior lateral line system The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001471 UBERON:2001470 biolink:AnatomicalEntity anterior lateral line The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001470 OBO:GOCHE_50248 biolink:OntologyClass substance with hematologic agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50248 3_STAR UBERON:2001472 biolink:AnatomicalEntity anterior lateral line neuromast Neuromast that is part of the anterior lateral line. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.) go-plus.json neuromast anterior http://purl.obolibrary.org/obo/UBERON_2001472 UBERON:2001468 biolink:AnatomicalEntity anterior lateral line system The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001468 CHEBI:2679 biolink:ChemicalSubstance amphetamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_2679 UBERON:0001015 biolink:AnatomicalEntity musculature A subdivision of the muscular system corresponding to a subdisivision of an organism. go-plus.json muscle group|set of skeletal muscles|musculature|musculature system|muscles set|muscles|musculi|muscle system|set of muscles http://purl.obolibrary.org/obo/UBERON_0001015 UBERON:0001017 biolink:AnatomicalEntity central nervous system The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. go-plus.json neuraxis|cerebrospinal axis|systema nervosum centrale|CNS http://purl.obolibrary.org/obo/UBERON_0001017 UBERON:0001016 biolink:AnatomicalEntity nervous system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. go-plus.json nerve net|neurological system|systema nervosum http://purl.obolibrary.org/obo/UBERON_0001016 UBERON:0001013 biolink:AnatomicalEntity adipose tissue Portion of connective tissue composed of adipocytes enmeshed in areolar tissue go-plus.json adipose|bodyfat|fatty depot|fat tissue|fatty tissue|fat http://purl.obolibrary.org/obo/UBERON_0001013 UBERON:2001457 biolink:AnatomicalEntity postcranial axial cartilage Cartilage which is part of the axial skeleton. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001457 UBERON:0001004 biolink:AnatomicalEntity respiratory system Functional system which consists of structures involved in respiration. go-plus.json systema respiratorium|apparatus respiratorius|apparatus respiratorius|Atmungssystem|respiratory system http://purl.obolibrary.org/obo/UBERON_0001004 UBERON:0001003 biolink:AnatomicalEntity skin epidermis The outer epithelial layer of the skin that is superficial to the dermis. go-plus.json epidermis|skin|vertebrate epidermis http://purl.obolibrary.org/obo/UBERON_0001003 UBERON:0001005 biolink:AnatomicalEntity respiratory airway An airway through which respiratory air passes in organisms. go-plus.json airways|airway http://purl.obolibrary.org/obo/UBERON_0001005 UBERON:0001000 biolink:AnatomicalEntity vas deferens A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct go-plus.json vas deferen|sperm duct|ductus deferens|vasa deferentia|deferent duct http://purl.obolibrary.org/obo/UBERON_0001000 UBERON:0001002 biolink:AnatomicalEntity cuticle tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]. go-plus.json cuticula|cuticular exoskeleton http://purl.obolibrary.org/obo/UBERON_0001002 UBERON:0001001 biolink:AnatomicalEntity chitin-based cuticle A cuticular covering that is composed primarily of chitin. The main structural component of arthropod cuticle is a polysaccharide, chitin, composed of N-acetylglucosamine units, together with proteins and lipids[WP]. go-plus.json exoskeleton|cuticle|insect cuticle|arthropod cuticle|arthropod exoskeleton http://purl.obolibrary.org/obo/UBERON_0001001 CHEBI:10436 biolink:ChemicalSubstance beta-ocimene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10436 chebi_ph7_3 UBERON:0001073 biolink:AnatomicalEntity ileocecal junction A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice go-plus.json ileocaecal junction http://purl.obolibrary.org/obo/UBERON_0001073 UBERON:0001072 biolink:AnatomicalEntity posterior vena cava A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart. go-plus.json posterior vena cava|inferior vena cava|postcava|caudal vena cava|inferior caval vein|vena cava inferior http://purl.obolibrary.org/obo/UBERON_0001072 UBERON:0001074 biolink:AnatomicalEntity pericardial cavity A potential space between the visceral and parietal layers of the pericardium. go-plus.json pericardial space|cavitas pericardiaca|cavity of pericardial sac http://purl.obolibrary.org/obo/UBERON_0001074 UBERON:0001071 biolink:AnatomicalEntity superficial cervical artery It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery. go-plus.json superficial branch of transverse cervical artery http://purl.obolibrary.org/obo/UBERON_0001071 UBERON:0001070 biolink:AnatomicalEntity external carotid artery A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP] go-plus.json external carotid|arteria carotis externa http://purl.obolibrary.org/obo/UBERON_0001070 UBERON:0001077 biolink:AnatomicalEntity transverse process of vertebra The transverse or costal processes of a vertebra, two in number, project one at either side from the point where the lamina joins the pedicle, between the superior and inferior articular processes. They serve for the attachment of muscles and ligaments. [WP,unvetted]. go-plus.json processus transversus|vertebra transverse process|transverse process|diapophyses|diapophysis|processus transversus vertebrae http://purl.obolibrary.org/obo/UBERON_0001077 UBERON:0001076 biolink:AnatomicalEntity neural spine A extension of a neural arches dorsal to the neural canal[TAO,modified]. go-plus.json spine of verterba|spinous process of vertebra|processus spinosus vertebrae|neural spine|vertebra spinous process|processus spinosus|spinous process|neural spines http://purl.obolibrary.org/obo/UBERON_0001076 UBERON:0001062 biolink:AnatomicalEntity anatomical entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. go-plus.json http://purl.obolibrary.org/obo/UBERON_0001062 UBERON:0001064 biolink:AnatomicalEntity ventral pancreatic duct A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. go-plus.json main pancreatic duct|canal of Wirsung|pancreatic duct|duct of Wirsung|hepaticopancreatic duct|ductus pancreatis ventralis|chief pancreatic duct http://purl.obolibrary.org/obo/UBERON_0001064 UBERON:0001068 biolink:AnatomicalEntity skin of back A zone of skin that is part of a back [Automatically generated definition]. go-plus.json back skin|skin, dorsal region|back zone of skin|zone of skin of back http://purl.obolibrary.org/obo/UBERON_0001068 UBERON:0001052 biolink:AnatomicalEntity rectum the terminal portion of the intestinal tube, terminating with the anus go-plus.json intestinum rectum|rectal sac|terminal portion of intestine|terminal portion of large intestine http://purl.obolibrary.org/obo/UBERON_0001052 UBERON:0001058 biolink:AnatomicalEntity mushroom body Prominent lobed neuropils found in annelids and all arthropods except crustaceans. They are thought to be involved in olfactory associative learning and memory[MESH] Mushroom body neuropils are divided into calyces, pedunculus, and its subsequent lobes. In Drosophila these are the alpha, beta, and gamma lobes. go-plus.json corpora pedunculata|mushroom bodies http://purl.obolibrary.org/obo/UBERON_0001058 UBERON:0001054 biolink:AnatomicalEntity Malpighian tubule A tubule that extends from the posterior part of the digestive tract which absorbs solutes, water, and wastes from the surrounding hemolymph. Each tubule consists of a single layer of cells that is closed off at the distal end with the proximal end joining the alimentary canal at the junction between the midgut and hindgut[WP,modified]. go-plus.json Malpighian tube|Malphigian tube|tuba Malpighii http://purl.obolibrary.org/obo/UBERON_0001054 UBERON:0001040 biolink:AnatomicalEntity yolk sac A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. go-plus.json saccus vitellinus|vesicula umbilicalis http://purl.obolibrary.org/obo/UBERON_0001040 CHEBI:10440 biolink:ChemicalSubstance (-)-beta-santalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10440 chebi_ph7_3 UBERON:0001042 biolink:AnatomicalEntity chordate pharynx A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. go-plus.json pharynx http://purl.obolibrary.org/obo/UBERON_0001042 UBERON:0001041 biolink:AnatomicalEntity foregut Anterior subdivision of a digestive tract. go-plus.json praeenteron|proenteron http://purl.obolibrary.org/obo/UBERON_0001041 CHEBI:10443 biolink:ChemicalSubstance (+)-beta-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10443 chebi_ph7_3 UBERON:0001048 biolink:AnatomicalEntity primordium Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. go-plus.json future organ|primordia|placode|bud|rudiment http://purl.obolibrary.org/obo/UBERON_0001048 UBERON:0001049 biolink:AnatomicalEntity neural tube In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. go-plus.json presumptive central nervous system|tubus neuralis|neural primordium http://purl.obolibrary.org/obo/UBERON_0001049 UBERON:0001044 biolink:AnatomicalEntity saliva-secreting gland saliva-secreting exocrine glands of the oral cavity[GO] go-plus.json salivary gland|glandulae salivariae http://purl.obolibrary.org/obo/UBERON_0001044 UBERON:0001043 biolink:AnatomicalEntity esophagus Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). go-plus.json oesophagus|gullet http://purl.obolibrary.org/obo/UBERON_0001043 PO:0020097 biolink:OntologyClass generative cell A spermatogenous cell (PO:0025525) of the microgametophyte (PO:0025280) that divides to produce two pollen sperm cells (PO:0025121). go-plus.json célula generativa (Spanish, exact)|雄原細胞、生殖系列細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020097 UBERON:0001046 biolink:AnatomicalEntity hindgut The caudalmost subdivision of a digestive tract. go-plus.json metenteron http://purl.obolibrary.org/obo/UBERON_0001046 UBERON:0001045 biolink:AnatomicalEntity midgut Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. go-plus.json mesenteron http://purl.obolibrary.org/obo/UBERON_0001045 PO:0020099 biolink:OntologyClass microgametophyte vegetative cell A native plant cell (PO:0025606) that is the larger cell of a microgametophyte (PO:0025280) in seed plants. It does not divide further and develops into a pollen tube cell (PO:0025195). go-plus.json célula vegetativa (Spanish, exact)|tube cell (related)|栄養細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0020099 UBERON:0005908 biolink:AnatomicalEntity conjunctival sac A serous sac which is the aggregate of the conjunctiva plus the conjunctival space go-plus.json subbrillar sac|conjunctiva serous sac http://purl.obolibrary.org/obo/UBERON_0005908 GO:0033529 biolink:BiologicalProcess raffinose biosynthetic process The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json raffinose synthesis|raffinose biosynthesis|raffinose formation|raffinose anabolism http://purl.obolibrary.org/obo/GO_0033529 GO:0033528 biolink:BiologicalProcess S-methylmethionine cycle A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level. MetaCyc:PWY-5441 go-plus.json http://purl.obolibrary.org/obo/GO_0033528 UBERON:0005906 biolink:AnatomicalEntity serous sac Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0005906 GO:0033527 biolink:BiologicalProcess tetrapyrrole biosynthetic process from glycine and succinyl-CoA The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA. MetaCyc:PWY-5189 go-plus.json tetrapyrrole anabolism from glycine and succinyl-CoA|tetrapyrrole synthesis from glycine and succinyl-CoA|tetrapyrrole biosynthesis from glycine and succinyl-CoA|tetrapyrrole formation from glycine and succinyl-CoA http://purl.obolibrary.org/obo/GO_0033527 GO:0033526 biolink:BiologicalProcess tetrapyrrole biosynthetic process from glutamate The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate. MetaCyc:PWY-5188 go-plus.json tetrapyrrole formation from glutamate|tetrapyrrole biosynthesis from glutamate|tetrapyrrole synthesis from glutamate|tetrapyrrole anabolism from glutamate http://purl.obolibrary.org/obo/GO_0033526 UBERON:0005904 biolink:AnatomicalEntity duct of male reproductive system Any of the ducts that are part of a male reproductive system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0005904 UBERON:0005903 biolink:AnatomicalEntity duct of seminal vesicle Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]. go-plus.json ductus excretorius glandulae vesiculosae|excretory duct of seminal gland|ductus excretorius (vesicula seminalis)|seminal vesicle duct|ductus excretorius glandulae vesiculosae http://purl.obolibrary.org/obo/UBERON_0005903 GO:0008569 biolink:MolecularActivity minus-end-directed microtubule motor activity A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis. MetaCyc:3.6.4.5-RXN|EC:5.6.1.4|EC:5.6.1.2 go-plus.json minus-end-directed kinesin ATPase activity|microtubule motor activity, minus-end-directed|kinesin ATP phosphohydrolase (minus-end-directed)|dynein ATPase|ATP-dependent microtubule motor activity, minus-end-directed|minus-end-directed ATP-dependent microtubule motor activity|ATP-dependent minus-end-directed microtubule motor activity http://purl.obolibrary.org/obo/GO_0008569 GO:0033525 biolink:BiologicalProcess sinapate ester biosynthetic process The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. MetaCyc:PWY-3301 go-plus.json sinapate ester anabolism|sinapate ester synthesis|sinapate ester formation|sinapate ester biosynthesis http://purl.obolibrary.org/obo/GO_0033525 PR:000020226 biolink:Protein islet amyloid polypeptide proteolytic cleavage product An islet amyloid polypeptide that has been processed by proteolytic cleavage. go-plus.json IAPP/ClvPrd http://purl.obolibrary.org/obo/PR_000020226 GO:0008568 biolink:MolecularActivity microtubule-severing ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP. Reactome:R-HSA-9668419|MetaCyc:3.6.4.3-RXN|EC:5.6.1.1 go-plus.json ATP phosphohydrolase (tubulin-dimerizing)|katanin activity http://purl.obolibrary.org/obo/GO_0008568 GO:0033524 biolink:BiologicalProcess sinapate ester metabolic process The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. go-plus.json sinapate ester metabolism http://purl.obolibrary.org/obo/GO_0033524 UBERON:0005902 biolink:AnatomicalEntity occipital region Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles. go-plus.json basicranial region|occipital region of head|occipital part of head|back of head http://purl.obolibrary.org/obo/UBERON_0005902 GO:0008567 biolink:MolecularActivity obsolete dynein ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome. go-plus.json dynein ATPase activity http://purl.obolibrary.org/obo/GO_0008567 GO:0008566 biolink:MolecularActivity mitochondrial protein-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex. EC:7.4.2.3|MetaCyc:3.6.3.51-RXN go-plus.json ATPase-coupled mitochondrial protein transporter activity http://purl.obolibrary.org/obo/GO_0008566 GO:0008565 biolink:MolecularActivity obsolete protein transporter activity OBSOLETE. Enables the directed movement of proteins into, out of or within a cell, or between cells. go-plus.json secretin|holin|enzyme transporter activity|protein transport chaperone http://purl.obolibrary.org/obo/GO_0008565 GO:0008564 biolink:MolecularActivity protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins. EC:7.4.2.8|MetaCyc:3.6.3.50-RXN go-plus.json ATPase-coupled protein transporter activity http://purl.obolibrary.org/obo/GO_0008564 GO:0008563 biolink:MolecularActivity obsolete alpha-factor sex pheromone exporter OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process. go-plus.json alpha-factor-transporting ATPase|alpha-factor sex pheromone exporter http://purl.obolibrary.org/obo/GO_0008563 CHEBI:83336 biolink:ChemicalSubstance 14-HPDHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83336 chebi_ph7_3 GO:0008562 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008562 CHEBI:83334 biolink:ChemicalSubstance 12-HPE(8,10,14)TrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83334 chebi_ph7_3 GO:0008561 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008561 GO:0008560 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008560 CHEBI:58376 biolink:ChemicalSubstance CMP-N-glycoloyl-beta-neuraminate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58376 chebi_ph7_3 GO:0008570 biolink:MolecularActivity obsolete myosin ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction. go-plus.json myosin ATPase activity http://purl.obolibrary.org/obo/GO_0008570 CHEBI:58375 biolink:ChemicalSubstance trans-4-hydroxy-L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58375 chebi_ph7_3 CHEBI:58374 biolink:ChemicalSubstance 3-ammoniopropanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_58374 chebi_ph7_3 CHEBI:58373 biolink:ChemicalSubstance 3-hexaprenyl-4,5-dihydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58373 chebi_ph7_3 CHEBI:58372 biolink:ChemicalSubstance 5-oxo-2,5-dihydro-2-furylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58372 chebi_ph7_3 CHEBI:58371 biolink:ChemicalSubstance 2-dehydro-3-deoxy-L-rhamnonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58371 chebi_ph7_3 CHEBI:58370 biolink:ChemicalSubstance dTTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58370 GO:0033523 biolink:BiologicalProcess histone H2B ubiquitination The modification of histone H2B by addition of ubiquitin groups. go-plus.json http://purl.obolibrary.org/obo/GO_0033523 UBERON:0005911 biolink:AnatomicalEntity endo-epithelium Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA] go-plus.json endoepithelium|endoderm-derived epithelium http://purl.obolibrary.org/obo/UBERON_0005911 GO:0033522 biolink:BiologicalProcess histone H2A ubiquitination The modification of histone H2A by addition of one or more ubiquitin groups. go-plus.json http://purl.obolibrary.org/obo/GO_0033522 GO:0033521 biolink:BiologicalProcess phytyl diphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate. MetaCyc:PWY-5063 go-plus.json phytyl diphosphate anabolism|phytyl diphosphate synthesis|phytyl diphosphate formation|phytyl diphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0033521 GO:0033520 biolink:BiologicalProcess phytol biosynthetic process The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol. go-plus.json phytol biosynthesis|phytol anabolism|phytol synthesis|phytol formation http://purl.obolibrary.org/obo/GO_0033520 CHEBI:58379 biolink:ChemicalSubstance deacetylipecoside(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58379 chebi_ph7_3 CHEBI:58378 biolink:ChemicalSubstance 2-dehydro-3-deoxy-D-fuconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58378 chebi_ph7_3 CHEBI:58377 biolink:ChemicalSubstance L-tyrosine methyl ester 4-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58377 chebi_ph7_3 GO:0033519 biolink:BiologicalProcess phytyl diphosphate metabolic process The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate. go-plus.json phytyl diphosphate metabolism http://purl.obolibrary.org/obo/GO_0033519 GO:0033518 biolink:BiologicalProcess myo-inositol hexakisphosphate dephosphorylation The process of removing one or more phosphate group from myo-inositol hexakisphosphate. MetaCyc:PWY-4702|MetaCyc:PWY-4781 go-plus.json phytate dephosphorylation http://purl.obolibrary.org/obo/GO_0033518 GO:0033517 biolink:BiologicalProcess myo-inositol hexakisphosphate metabolic process The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds. go-plus.json myo-inositol hexakisphosphate metabolism|phytate metabolism|phytate metabolic process http://purl.obolibrary.org/obo/GO_0033517 GO:0033516 biolink:BiologicalProcess L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine. MetaCyc:PWY-702 go-plus.json methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine formation from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-phospho-L-homoserine and cystathionine http://purl.obolibrary.org/obo/GO_0033516 GO:0033515 biolink:BiologicalProcess L-lysine catabolic process using lysine 6-aminotransferase The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase. MetaCyc:PWY-5298 go-plus.json L-lysine degradation using lysine 6-aminotransferase|L-lysine breakdown using lysine 6-aminotransferase http://purl.obolibrary.org/obo/GO_0033515 GO:0033514 biolink:BiologicalProcess L-lysine catabolic process to acetyl-CoA via L-pipecolate The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate. MetaCyc:PWY-5283 go-plus.json L-lysine breakdown to acetyl-CoA via L-pipecolate|L-lysine degradation to acetyl-CoA via L-pipecolate http://purl.obolibrary.org/obo/GO_0033514 GO:0008579 biolink:MolecularActivity JUN kinase phosphatase activity Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0008579 GO:0033513 biolink:BiologicalProcess L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide. MetaCyc:PWY-5280 go-plus.json L-lysine degradation to acetyl-CoA via 5-aminopentanamide|L-lysine breakdown to acetyl-CoA via 5-aminopentanamide http://purl.obolibrary.org/obo/GO_0033513 GO:0008578 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008578 GO:0008577 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008577 GO:0008576 biolink:MolecularActivity obsolete vesicle-fusing ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. go-plus.json vesicle-fusing ATPase activity http://purl.obolibrary.org/obo/GO_0008576 CHEBI:83349 biolink:ChemicalSubstance divinyl chlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83349 chebi_ph7_3 GO:0008575 biolink:MolecularActivity obsolete proteasome ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome. go-plus.json proteasome ATPase activity http://purl.obolibrary.org/obo/GO_0008575 CHEBI:83348 biolink:ChemicalSubstance chlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83348 chebi_ph7_3 GO:0008574 biolink:MolecularActivity plus-end-directed microtubule motor activity A motor activity that generates movement along a microtubule toward the plus end, driven by ATP hydrolysis. MetaCyc:3.6.4.4-RXN|EC:5.6.1.3 go-plus.json ATP-dependent microtubule motor activity, plus-end-directed|microtubule motor activity, plus-end-directed|kinesin activity|plus-end-directed kinesin ATPase activity|plus-end-directed ATP-dependent microtubule motor activity|ATP-dependent plus-end-directed microtubule motor activity|kinesin ATP phosphohydrolase (plus-end-directed) http://purl.obolibrary.org/obo/GO_0008574 CHEBI:83347 biolink:ChemicalSubstance organosulfonic ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_83347 chebi_ph7_3 GO:0008573 biolink:MolecularActivity obsolete peroxisome-assembly ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle. go-plus.json peroxisome-assembly ATPase activity http://purl.obolibrary.org/obo/GO_0008573 GO:0008572 biolink:MolecularActivity obsolete nucleoplasmin ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes. go-plus.json nucleoplasmin ATPase activity http://purl.obolibrary.org/obo/GO_0008572 GO:0008571 biolink:MolecularActivity obsolete non-chaperonin molecular chaperone ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin. go-plus.json non-chaperonin molecular chaperone ATPase activity http://purl.obolibrary.org/obo/GO_0008571 CHEBI:83344 biolink:ChemicalSubstance 8-HPETE methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_83344 chebi_ph7_3 GO:0008581 biolink:MolecularActivity obsolete ubiquitin-specific protease 5 activity OBSOLETE. Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin. go-plus.json ubiquitin isopeptidase T activity|ubiquitin-specific protease 5 activity http://purl.obolibrary.org/obo/GO_0008581 CHEBI:83343 biolink:ChemicalSubstance 12(R)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83343 chebi_ph7_3 CHEBI:58365 biolink:ChemicalSubstance 4-guanidiniumylbutanamide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58365 chebi_ph7_3 GO:0008580 biolink:MolecularActivity obsolete cytoskeletal regulator activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytoskeletal regulator activity http://purl.obolibrary.org/obo/GO_0008580 CHEBI:83342 biolink:ChemicalSubstance 10-HPO(6,8,12)TrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83342 chebi_ph7_3 CHEBI:58363 biolink:ChemicalSubstance oxamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58363 chebi_ph7_3 CHEBI:58361 biolink:ChemicalSubstance diphthinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58361 chebi_ph7_3 CHEBI:58360 biolink:ChemicalSubstance 1-aminocyclopropanecarboxylic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58360 chebi_ph7_3 OBO:D96882F1-8709-49AB-BCA9-772A67EA6C33 biolink:OntologyClass alobate nucleus go-plus.json http://purl.obolibrary.org/obo/D96882F1-8709-49AB-BCA9-772A67EA6C33 GO:0033512 biolink:BiologicalProcess L-lysine catabolic process to acetyl-CoA via saccharopine The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine. MetaCyc:LYSINE-DEG1-PWY go-plus.json L-lysine breakdown to acetyl-CoA via saccharopine|L-lysine degradation to acetyl-CoA via saccharopine http://purl.obolibrary.org/obo/GO_0033512 GO:0033511 biolink:BiologicalProcess luteolin biosynthetic process The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one. MetaCyc:PWY-5060 go-plus.json luteolin biosynthesis|luteolin synthesis|luteolin formation|luteolin anabolism http://purl.obolibrary.org/obo/GO_0033511 GO:0033510 biolink:BiologicalProcess luteolin metabolic process The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one. go-plus.json luteolin metabolism http://purl.obolibrary.org/obo/GO_0033510 CHEBI:58369 biolink:ChemicalSubstance dTDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58369 chebi_ph7_3 OBO:GOCHE_25442 biolink:OntologyClass substance with mycotoxin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_25442 3_STAR CHEBI:58367 biolink:ChemicalSubstance UDP-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58367 chebi_ph7_3 CHEBI:58366 biolink:ChemicalSubstance deacetylcephalosporin C(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58366 chebi_ph7_3 GO:0033509 biolink:BiologicalProcess glutamate catabolic process to propionate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate. MetaCyc:PWY-5088 go-plus.json glutamate degradation to propionate|glutamate breakdown to propionate http://purl.obolibrary.org/obo/GO_0033509 GO:0033508 biolink:BiologicalProcess glutamate catabolic process to butyrate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate. MetaCyc:PWY-5087 go-plus.json glutamate degradation to butyrate|glutamate breakdown to butyrate http://purl.obolibrary.org/obo/GO_0033508 GO:0033507 biolink:BiologicalProcess glucosinolate biosynthetic process from phenylalanine The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine. MetaCyc:PWY-2821 go-plus.json glucosinolate formation from phenylalanine|glucosinolate synthesis from phenylalanine|glucosinolate anabolism from phenylalanine|glucosinolate biosynthesis from phenylalanine http://purl.obolibrary.org/obo/GO_0033507 GO:0033506 biolink:BiologicalProcess glucosinolate biosynthetic process from homomethionine The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine. MetaCyc:PWY-1187 go-plus.json glucosinolate biosynthesis from homomethionine|glucosinolate anabolism from homomethionine|glucosinolate synthesis from homomethionine|glucosinolate formation from homomethionine http://purl.obolibrary.org/obo/GO_0033506 GO:0008549 biolink:MolecularActivity obsolete dynamin GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles. go-plus.json dynamine GTPase activity|dynamin GTPase activity http://purl.obolibrary.org/obo/GO_0008549 GO:0033505 biolink:BiologicalProcess floor plate morphogenesis The process in which the anatomical structure of the floor plate is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0033505 GO:0033504 biolink:BiologicalProcess floor plate development The progression of the floor plate over time from its initial formation until its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0033504 GO:0008548 biolink:MolecularActivity obsolete signal-recognition-particle GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis. go-plus.json signal-recognition-particle GTPase activity http://purl.obolibrary.org/obo/GO_0008548 GO:0008547 biolink:MolecularActivity obsolete protein-synthesizing GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs. go-plus.json protein-synthesizing GTPase activity http://purl.obolibrary.org/obo/GO_0008547 GO:0033503 biolink:CellularComponent HULC complex A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2. go-plus.json http://purl.obolibrary.org/obo/GO_0033503 GO:0008546 biolink:BiologicalProcess obsolete microtubule/chromatin interaction OBSOLETE. Physical interaction between microtubules and chromatin via DNA binding proteins. go-plus.json microtubule/chromatin interaction http://purl.obolibrary.org/obo/GO_0008546 GO:0033502 biolink:BiologicalProcess cellular galactose homeostasis A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment. go-plus.json cell galactose homeostasis http://purl.obolibrary.org/obo/GO_0033502 GO:0008545 biolink:MolecularActivity JUN kinase kinase activity Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase. Reactome:R-HSA-168162 go-plus.json JNKK http://purl.obolibrary.org/obo/GO_0008545 GO:0008544 biolink:BiologicalProcess epidermis development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. go-plus.json hypodermis development http://purl.obolibrary.org/obo/GO_0008544 GO:0008543 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. go-plus.json FGF receptor signalling pathway|FGFR signaling pathway|fibroblast growth factor receptor signalling pathway|FGF receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008543 GO:0008542 biolink:BiologicalProcess visual learning Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue. go-plus.json spatial learning http://purl.obolibrary.org/obo/GO_0008542 CHEBI:83358 biolink:ChemicalSubstance N-stearoylsphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83358 chebi_ph7_3 GO:0008541 biolink:CellularComponent proteasome regulatory particle, lid subcomplex The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex. go-plus.json http://purl.obolibrary.org/obo/GO_0008541 CHEBI:83357 biolink:ChemicalSubstance 7(1)-hydroxychlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83357 chebi_ph7_3 GO:0008540 biolink:CellularComponent proteasome regulatory particle, base subcomplex The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex. go-plus.json http://purl.obolibrary.org/obo/GO_0008540 CHEBI:83356 biolink:ChemicalSubstance chlorophyllide b(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83356 chebi_ph7_3 CHEBI:58354 biolink:ChemicalSubstance 4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58354 chebi_ph7_3 CHEBI:58353 biolink:ChemicalSubstance quercetin-7-olate 3,4'-bissulfate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58353 chebi_ph7_3 CHEBI:58352 biolink:ChemicalSubstance 2-hydroxypropyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58352 chebi_ph7_3 PR:000010877 biolink:Protein myogenin A protein that is a translation product of the human MYOG gene or a 1:1 ortholog thereof. go-plus.json MYF4|bHLHc3|class C basic helix-loop-helix protein 3|MYOD1-related protein|MYOG|Myf-4|myogenic factor 4 http://purl.obolibrary.org/obo/PR_000010877 CHEBI:58351 biolink:ChemicalSubstance sirohydrochlorin(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58351 chebi_ph7_3 CHEBI:83350 biolink:ChemicalSubstance protochlorophyllide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83350 chebi_ph7_3 UBERON:2001626 biolink:AnatomicalEntity premaxillary tooth Tooth that is attached to the premaxilla. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001626 GO:0033501 biolink:BiologicalProcess galactose homeostasis A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0033501 GO:0033500 biolink:BiologicalProcess carbohydrate homeostasis A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0033500 CHEBI:58359 biolink:ChemicalSubstance L-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58359 chebi_ph7_3 CHEBI:58358 biolink:ChemicalSubstance 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58358 chebi_ph7_3 CHEBI:58357 biolink:ChemicalSubstance erythro-5-hydroxy-L-lysinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58357 chebi_ph7_3 CHEBI:58356 biolink:ChemicalSubstance N-phosphonato-L-lombricine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58356 chebi_ph7_3 CHEBI:58355 biolink:ChemicalSubstance GDP-L-galactose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58355 chebi_ph7_3 GO:0008559 biolink:MolecularActivity ABC-type xenobiotic transporter activity Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). MetaCyc:3.6.3.44-RXN|EC:7.6.2.2 go-plus.json pleiotropic-drug-resistance protein|PDR protein|xenobiotic transmembrane transporting ATPase activity|P-glycoprotein|MDR protein|multidrug resistance exporter|ATP-dependent xenobiotic transmembrane transporter activity|ATPase-coupled xenobiotic transmembrane transporter activity|xenobiotic ABC transporter|ATP phosphohydrolase (xenobiotic-exporting)|multidrug-resistance protein http://purl.obolibrary.org/obo/GO_0008559 GO:0008558 biolink:MolecularActivity ABC-type guanine transporter activity Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in). MetaCyc:3.6.3.37-RXN|RHEA:20832|EC:7.6.2.6 go-plus.json ATPase-coupled guanine transmembrane transporter activity|ATP-dependent guanine transmembrane transporter activity|guanine ABC transporter|guanine-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0008558 GO:0008557 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008557 GO:0008556 biolink:MolecularActivity P-type potassium transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). EC:7.2.2.6|RHEA:16777 go-plus.json potassium-uptake-ATPase activity|K(+)-transporting ATPase activity|K+-transporting ATPase activity|potassium transporting ATPase activity|ATP-dependent potassium transmembrane transporter activity|potassium transmembrane transporter activity, phosphorylative mechanism|ATPase-coupled potassium transmembrane transporter activity|ATP phosphohydrolase (K+-importing)|potassium ABC transporter|K(+)-importing ATPase activity|K+-importing ATPase activity|potassium-transporting ATPase activity|potassium-importing ATPase activity http://purl.obolibrary.org/obo/GO_0008556 GO:0008555 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008555 GO:0008554 biolink:MolecularActivity P-type sodium transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism. RHEA:14633|EC:7.2.2.3|MetaCyc:3.6.3.7-RXN go-plus.json Na+-transporting ATPase activity|sodium exporting ATPase activity, phosphorylative mechanism|sodium transmembrane transporter activity, phosphorylative mechanism|sodium transport ATPase activity|sodium-translocating P-type ATPase activity|sodium-exporting ATPase activity|Na+-exporting ATPase activity|sodium-exporting ATPase activity, phosphorylative mechanism|Na(+)-exporting ATPase activity|Na(+)-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0008554 GO:0008553 biolink:MolecularActivity P-type proton-exporting transporter activity Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle. EC:7.1.2.1|MetaCyc:3.6.3.6-RXN|RHEA:20852 go-plus.json proton-transporting ATPase activity|H+-exporting ATPase activity|H(+)-transporting ATPase activity|P-type H(+)-exporting ATPase activity|hydrogen-exporting ATPase activity, phosphorylative mechanism|proton-exporting ATPase activity, phosphorylative mechanism|hydrogen-/sodium-translocating ATPase activity|hydrogen exporting ATPase activity, phosphorylative mechanism|H+-transporting ATPase|proton-exporting ATPase activity|proton-translocating ATPase activity|proton transport ATPase activity|hydrogen-exporting ATPase activity http://purl.obolibrary.org/obo/GO_0008553 GO:0008552 biolink:MolecularActivity obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+. go-plus.json zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity http://purl.obolibrary.org/obo/GO_0008552 GO:0008551 biolink:MolecularActivity P-type cadmium transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out). MetaCyc:3.6.3.3-RXN|EC:7.2.2.21|RHEA:12132 go-plus.json Cd(2+)-exporting ATPase activity|cadmium exporting ATPase activity|cadmium-exporting ATPase activity|cadmium transmembrane transporter activity, phosphorylative mechanism|Cd2+-exporting ATPase activity|cadmium-translocating P-type ATPase activity http://purl.obolibrary.org/obo/GO_0008551 GO:0008550 biolink:MolecularActivity obsolete tubulin GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. go-plus.json tubulin GTPase activity http://purl.obolibrary.org/obo/GO_0008550 CHEBI:58343 biolink:ChemicalSubstance adenosine 3',5'-bismonophosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58343 chebi_ph7_3 CHEBI:58342 biolink:ChemicalSubstance acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58342 chebi_ph7_3 CHEBI:58341 biolink:ChemicalSubstance UDP-L-arabinose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58341 chebi_ph7_3 CHEBI:58340 biolink:ChemicalSubstance O-acetyl-L-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58340 chebi_ph7_3 CHEBI:83360 biolink:ChemicalSubstance N-lignoceroylsphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83360 chebi_ph7_3 PR:000010882 biolink:Protein myozenin-1 A protein that is a translation product of the human MYOZ1 gene or a 1:1 ortholog thereof. go-plus.json protein FATZ|MYOZ1|calsarcin-2|MYOZ|filamin-, actinin- and telethonin-binding protein http://purl.obolibrary.org/obo/PR_000010882 CHEBI:58349 biolink:ChemicalSubstance NADP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58349 chebi_ph7_3 CHEBI:58348 biolink:ChemicalSubstance 3-[hydroxy(oxido)phosphoranyl]pyruvate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58348 chebi_ph7_3 CHEBI:58346 biolink:ChemicalSubstance 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58346 chebi_ph7_3 CHEBI:58345 biolink:ChemicalSubstance D-ribose 1,5-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58345 chebi_ph7_3 CHEBI:58344 biolink:ChemicalSubstance 3-(3,4-dioxidopyridinium-1-yl)-L-alanine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58344 GO:0008529 biolink:MolecularActivity obsolete endogenous peptide receptor activity OBSOLETE. Combining with an intracellular peptide to initiate a change in cell activity. go-plus.json endogenous peptide receptor activity http://purl.obolibrary.org/obo/GO_0008529 GO:0008528 biolink:MolecularActivity G protein-coupled peptide receptor activity Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json peptide receptor activity, G-protein coupled|peptide receptor activity, G protein coupled|G protein coupled peptide receptor activity|G-protein coupled peptide receptor activity http://purl.obolibrary.org/obo/GO_0008528 GO:0008527 biolink:MolecularActivity taste receptor activity Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste. go-plus.json gustatory receptor http://purl.obolibrary.org/obo/GO_0008527 PR:000020267 biolink:Protein insulin-like growth factor II proteolytic cleavage product An insulin-like growth factor II that has been processed by proteolytic cleavage. go-plus.json IGF2/ClvPrd http://purl.obolibrary.org/obo/PR_000020267 GO:0008526 biolink:MolecularActivity phosphatidylinositol transfer activity Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Reactome:R-HSA-8874470|Reactome:R-HSA-8869241 go-plus.json intermembrane phosphotidylinositol transfer activity|phosphatidylinositol carrier activity|phosphatidylinositol transfer activity|phosphatidylinositol transporter activity|intermembrane phosphatidylinositol transfer activity http://purl.obolibrary.org/obo/GO_0008526 GO:0008525 biolink:MolecularActivity phosphatidylcholine transporter activity Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. go-plus.json phosphatidylcholine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008525 UBERON:0005946 biolink:AnatomicalEntity outflow tract of atrium An outflow tract that is part of a cardiac atrium. go-plus.json outflow part of atrium http://purl.obolibrary.org/obo/UBERON_0005946 GO:0008524 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008524 GO:0008523 biolink:MolecularActivity sodium-dependent multivitamin transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate. Reactome:R-HSA-199219|Reactome:R-HSA-429581|Reactome:R-HSA-199206 go-plus.json http://purl.obolibrary.org/obo/GO_0008523 GO:0008522 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008522 GO:0008521 biolink:MolecularActivity acetyl-CoA transmembrane transporter activity Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. Reactome:R-HSA-727759|Reactome:R-HSA-5649742 go-plus.json acetyl-CoA transporter activity http://purl.obolibrary.org/obo/GO_0008521 GO:0008520 biolink:MolecularActivity L-ascorbate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in). TC:2.A.40.6.1 go-plus.json sodium-dependent L-ascorbic acid transporter|sodium-dependent L-ascorbate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008520 CHEBI:83377 biolink:ChemicalSubstance 7(1)-hydroxychlorophyll a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83377 chebi_ph7_3 CHEBI:58332 biolink:ChemicalSubstance CDP-diacylglycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58332 chebi_ph7_3 CHEBI:58331 biolink:ChemicalSubstance farnesyl triphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58331 CHEBI:83374 biolink:ChemicalSubstance all-cis-polyprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83374 chebi_ph7_3 CHEBI:58330 biolink:ChemicalSubstance 1-alpha-D-galactosyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58330 chebi_ph7_3 CHEBI:83373 biolink:ChemicalSubstance 3-vinylbacteriochlorophyllide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83373 chebi_ph7_3 NCBITaxon:94695 biolink:OrganismalEntity Methanosarcinales go-plus.json Halomebacteria http://purl.obolibrary.org/obo/NCBITaxon_94695 CHEBI:34368 biolink:ChemicalSubstance stilbene-4,4'-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34368 chebi_ph7_3 UBERON:0005956 biolink:AnatomicalEntity outflow part of left ventricle Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta. go-plus.json vestibulum aortae|left ventricular outflow tract|outflow tract of left ventricle|aortic vestibule|LVOT|Sibson vestibule|left ventricular outflow|heart left ventricle outflow tract http://purl.obolibrary.org/obo/UBERON_0005956 CHEBI:58339 biolink:ChemicalSubstance 3'-phosphonato-5'-adenylyl sulfate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58339 chebi_ph7_3 UBERON:0005953 biolink:AnatomicalEntity outflow part of right ventricle Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk go-plus.json right ventricle pulmonary outflow tract|pulmonary conus|pulmonary cone|arterial cone|conus arteriosus|conus arteriosus (infundibulum)|outflow tract of right ventricle|infundibulum of right ventricle|right ventricular outflow tract|RVOT|infundibulum|pulmonary conus http://purl.obolibrary.org/obo/UBERON_0005953 CHEBI:58337 biolink:ChemicalSubstance 5,10-(methanylylidene)tetrahydromethanopterin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58337 chebi_ph7_3 CHEBI:58336 biolink:ChemicalSubstance alpha-D-galactose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58336 chebi_ph7_3 CHEBI:58335 biolink:ChemicalSubstance sedoheptulose 1,7-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58335 chebi_ph7_3 CHEBI:58334 biolink:ChemicalSubstance cyclohexyl isocyanide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58334 chebi_ph7_3 CHEBI:58333 biolink:ChemicalSubstance isoorientin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58333 chebi_ph7_3 GO:0008539 biolink:MolecularActivity obsolete proteasome inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis. go-plus.json proteasome inhibitor activity|PI-31 http://purl.obolibrary.org/obo/GO_0008539 GO:0008538 biolink:MolecularActivity obsolete proteasome activator activity OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis. go-plus.json proteasome activator activity|PA28 http://purl.obolibrary.org/obo/GO_0008538 GO:0008537 biolink:CellularComponent proteasome activator complex A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex. go-plus.json PA28 http://purl.obolibrary.org/obo/GO_0008537 GO:0008536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008536 GO:0008535 biolink:BiologicalProcess respiratory chain complex IV assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms. go-plus.json cytochrome c oxidase complex assembly|cytochrome c oxidase biogenesis http://purl.obolibrary.org/obo/GO_0008535 GO:0008534 biolink:MolecularActivity oxidized purine nucleobase lesion DNA N-glycosylase activity Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site. Reactome:R-HSA-110229|MetaCyc:3.2.2.23-RXN|EC:3.2.2.23|Reactome:R-HSA-110243|Reactome:R-HSA-110244 go-plus.json 8-oxoguanine DNA glycosylase activity|DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]|purine-specific oxidized base lesion DNA N-glycosylase activity|Fpg protein|2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity|formamidopyrimidine-DNA glycosylase activity|DNA-formamidopyrimidine glycosylase activity|deoxyribonucleate glycosidase activity|bifunctional DNA glycosylase activity|2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity|Fapy-DNA glycosylase activity|DNA glycosylase/AP-lyase activity|DNA glycosylase/beta-lyase activity|oxidized purine base lesion DNA N-glycosylase activity http://purl.obolibrary.org/obo/GO_0008534 GO:0008533 biolink:MolecularActivity obsolete astacin activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'. go-plus.json astacin activity|astacus proteinase activity|Astacus proteinase activity|crayfish small-molecule proteinase activity http://purl.obolibrary.org/obo/GO_0008533 GO:0008532 biolink:MolecularActivity N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R. RHEA:14389|EC:2.4.1.149|Reactome:R-HSA-2025724|MetaCyc:2.4.1.149-RXN go-plus.json uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase|GnTE activity|N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity|UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity|galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity|poly-N-acetyllactosamine extension enzyme activity|UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0008532 GO:0008531 biolink:MolecularActivity riboflavin kinase activity Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+). Reactome:R-HSA-196964|MetaCyc:RIBOFLAVINKIN-RXN|KEGG_REACTION:R00549|EC:2.7.1.26|RHEA:14357 go-plus.json riboflavine kinase activity|riboflavin kinase (phosphorylating)|ATP:riboflavin 5'-phosphotransferase activity|FK|flavokinase activity http://purl.obolibrary.org/obo/GO_0008531 GO:0008530 biolink:MolecularActivity obsolete exogenous peptide receptor activity OBSOLETE. Combining with an extracellular peptide to initiate a change in cell activity. go-plus.json exogenous peptide receptor activity http://purl.obolibrary.org/obo/GO_0008530 CHEBI:83389 biolink:ChemicalSubstance furan-2,5-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83389 chebi_ph7_3 CHEBI:83388 biolink:ChemicalSubstance 5-(dihydroxymethyl)-2-furoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83388 chebi_ph7_3 CHEBI:58321 biolink:ChemicalSubstance L-allysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58321 chebi_ph7_3 CHEBI:83387 biolink:ChemicalSubstance 5-formyl-2-furoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83387 chebi_ph7_3 UBERON:2001632 biolink:AnatomicalEntity ectopterygoid tooth Tooth that is attached to the ectopterygoid bone. go-plus.json http://purl.obolibrary.org/obo/UBERON_2001632 CHEBI:83386 biolink:ChemicalSubstance 2-(dihydroxymethyl)-5-formylfuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_83386 chebi_ph7_3 CHEBI:58320 biolink:ChemicalSubstance ammonioacetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_58320 chebi_ph7_3 CHEBI:83385 biolink:ChemicalSubstance 2,5-diformylfuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_83385 chebi_ph7_3 CHEBI:83384 biolink:ChemicalSubstance D-glucaro-1,5-lactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83384 chebi_ph7_3 CHEBI:83383 biolink:ChemicalSubstance D-galactaro-1,5-lactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83383 chebi_ph7_3 CHEBI:58329 biolink:ChemicalSubstance (+)-taxifolin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58329 UBERON:0005945 biolink:AnatomicalEntity neurocranial trabecula go-plus.json trabecula|neurocranial trabeculae|trabecular cartilage http://purl.obolibrary.org/obo/UBERON_0005945 UBERON:0005944 biolink:AnatomicalEntity axial skeleton plus cranial skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. go-plus.json skeleton axiale http://purl.obolibrary.org/obo/UBERON_0005944 CHEBI:58328 biolink:ChemicalSubstance D-allose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58328 chebi_ph7_3 CHEBI:58326 biolink:ChemicalSubstance N(omega),N(omega)-dimethyl-L-argininium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58326 chebi_ph7_3 CHEBI:58325 biolink:ChemicalSubstance 1-ammonio-1-deoxy-scyllo-inositol 4-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58325 chebi_ph7_3 CHEBI:58324 biolink:ChemicalSubstance N(1)-acetylspermidinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58324 chebi_ph7_3 CHEBI:383703 biolink:ChemicalSubstance 3,6-diamino-10-methylacridinium chloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_383703 CHEBI:58323 biolink:ChemicalSubstance hydrogenobyrinate(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58323 CHEBI:58322 biolink:ChemicalSubstance 3-mercapto-2-mercaptomethylpropanoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58322 chebi_ph7_3 CHEBI:48995 biolink:ChemicalSubstance 5-hydroxyquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48995 chebi_ph7_3 GO:0008509 biolink:MolecularActivity anion transmembrane transporter activity Enables the transfer of a negatively charged ion from one side of a membrane to the other. Reactome:R-HSA-166214 go-plus.json anion transporter activity http://purl.obolibrary.org/obo/GO_0008509 GO:0008508 biolink:MolecularActivity bile acid:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in). Reactome:R-HSA-194121|Reactome:R-HSA-433089|Reactome:R-HSA-194187 go-plus.json sodium/bile acid symporter activity http://purl.obolibrary.org/obo/GO_0008508 CHEBI:48994 biolink:ChemicalSubstance quinolin-6-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48994 chebi_ph7_3 GO:0008507 biolink:MolecularActivity sodium:iodide symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in). Reactome:R-HSA-5658195|Reactome:R-HSA-429591 go-plus.json sodium/iodide symporter activity http://purl.obolibrary.org/obo/GO_0008507 UBERON:0005928 biolink:AnatomicalEntity external naris A naris that provides one of the small external openings of the head that give passage to air for breathing. go-plus.json blowhole|nostril|anterior nares|naris|anterior naris|external nares http://purl.obolibrary.org/obo/UBERON_0005928 CHEBI:48996 biolink:ChemicalSubstance 6-hydroxyquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48996 chebi_ph7_3 GO:0008506 biolink:MolecularActivity sucrose:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in). go-plus.json sucrose:hydrogen symporter activity|hydrogen/sucrose transporter activity http://purl.obolibrary.org/obo/GO_0008506 GO:0008505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008505 CHEBI:48999 biolink:ChemicalSubstance 4-hydroxyphenylacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48999 chebi_ph7_3 GO:0008504 biolink:MolecularActivity monoamine transmembrane transporter activity Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other. Reactome:R-HSA-380620|Reactome:R-HSA-379393|Reactome:R-HSA-444160|Reactome:R-HSA-5660706|Reactome:R-HSA-380586|Reactome:R-HSA-372542 go-plus.json http://purl.obolibrary.org/obo/GO_0008504 GO:0008503 biolink:MolecularActivity benzodiazepine receptor activity Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0008503 GO:0008502 biolink:MolecularActivity melatonin receptor activity Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. go-plus.json http://purl.obolibrary.org/obo/GO_0008502 CHEBI:58319 biolink:ChemicalSubstance coenzyme M(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58319 chebi_ph7_3 GO:0008501 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008501 GO:0008500 biolink:MolecularActivity obsolete glycine-, glutamate-, thienylcyclohexylpiperidine binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json glycine-, glutamate-, thienylcyclohexylpiperidine binding http://purl.obolibrary.org/obo/GO_0008500 CHEBI:48991 biolink:ChemicalSubstance 7-methylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48991 chebi_ph7_3 CHEBI:48990 biolink:ChemicalSubstance 8-chloroquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48990 chebi_ph7_3 CHEBI:48993 biolink:ChemicalSubstance quinolin-5-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48993 chebi_ph7_3 CHEBI:83399 biolink:ChemicalSubstance marine xenobiotic metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_83399 CHEBI:58310 biolink:ChemicalSubstance N(2)-phenylacetyl-L-glutaminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58310 chebi_ph7_3 CHEBI:34342 biolink:ChemicalSubstance 3-methylcholanthrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_34342 chebi_ph7_3 CHEBI:83397 biolink:ChemicalSubstance L-citrulline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83397 chebi_ph7_3 CHEBI:83390 biolink:ChemicalSubstance pentachlorobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_83390 CHEBI:58318 biolink:ChemicalSubstance N-carbamoylputrescinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58318 chebi_ph7_3 CHEBI:58315 biolink:ChemicalSubstance L-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58315 chebi_ph7_3 CHEBI:58314 biolink:ChemicalSubstance (2R)-2-hydroxy monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58314 chebi_ph7_3 CHEBI:58313 biolink:ChemicalSubstance L-rhamnulose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58313 chebi_ph7_3 CHEBI:58312 biolink:ChemicalSubstance 6-phosphonato-beta-D-glucosyl-(1->4)-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58312 chebi_ph7_3 CHEBI:58311 biolink:ChemicalSubstance (2R)-CDP-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58311 chebi_ph7_3 CHEBI:48984 biolink:ChemicalSubstance 8-methylquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48984 chebi_ph7_3 GO:0008519 biolink:MolecularActivity ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals. RHEA:28747|Reactome:R-HSA-446278|Reactome:R-HSA-444393|Reactome:R-HSA-444419|Reactome:R-HSA-5623051|Reactome:R-HSA-444416|Reactome:R-HSA-446277 go-plus.json ammonia transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008519 CHEBI:48983 biolink:ChemicalSubstance 4-methylquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48983 chebi_ph7_3 GO:0008518 biolink:MolecularActivity folate:anion antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF. TC:2.A.48 go-plus.json reduced folate transmembrane transporter activity|reduced folate transporter|reduced folate carrier activity http://purl.obolibrary.org/obo/GO_0008518 CHEBI:48986 biolink:ChemicalSubstance 4-methylquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48986 chebi_ph7_3 CHEBI:48985 biolink:ChemicalSubstance 8-chloroquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48985 chebi_ph7_3 GO:0008517 biolink:MolecularActivity folic acid transmembrane transporter activity Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. Reactome:R-HSA-200729|Reactome:R-HSA-200652|Reactome:R-HSA-200720|Reactome:R-HSA-200680|Reactome:R-HSA-200646 go-plus.json folate transmembrane transporter activity|folate transporter activity|vitamin M transporter activity|vitamin B9 transporter activity|folic acid transporter activity http://purl.obolibrary.org/obo/GO_0008517 CHEBI:48988 biolink:ChemicalSubstance 8-hydroxyquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48988 chebi_ph7_3 GO:0008516 biolink:MolecularActivity hexose uniporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in). go-plus.json http://purl.obolibrary.org/obo/GO_0008516 GO:0008515 biolink:MolecularActivity sucrose transmembrane transporter activity Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane. go-plus.json sucrose permease (PTS) activity|sucrose permease activity http://purl.obolibrary.org/obo/GO_0008515 CHEBI:48987 biolink:ChemicalSubstance 7-hydroxyquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48987 chebi_ph7_3 GO:0008514 biolink:MolecularActivity organic anion transmembrane transporter activity Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. Reactome:R-HSA-2142859 go-plus.json http://purl.obolibrary.org/obo/GO_0008514 CHEBI:58309 biolink:ChemicalSubstance UDP-N-acetylmuramate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58309 chebi_ph7_3 GO:0008513 biolink:MolecularActivity secondary active organic cation transmembrane transporter activity Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. Reactome:R-HSA-549241 go-plus.json organic cation porter activity|polyspecific organic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008513 CHEBI:48989 biolink:ChemicalSubstance 8-methylquinolin-2(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_48989 chebi_ph7_3 UBERON:0005913 biolink:AnatomicalEntity zone of bone organ go-plus.json bone organ zone http://purl.obolibrary.org/obo/UBERON_0005913 CHEBI:58308 biolink:ChemicalSubstance 5-amino-4-chloro-2-(2-oxidomuconoyl)pyridazin-3(2H)-one(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58308 chebi_ph7_3 GO:0008512 biolink:MolecularActivity sulfate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). go-plus.json sulfate/hydrogen symporter activity|sulfate:hydrogen symporter activity|sulphate:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0008512 GO:0008511 biolink:MolecularActivity sodium:potassium:chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in). Reactome:R-HSA-5623588|Reactome:R-HSA-426086 go-plus.json sodium/potassium/chloride symporter activity http://purl.obolibrary.org/obo/GO_0008511 GO:0008510 biolink:MolecularActivity sodium:bicarbonate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in). Reactome:R-HSA-425483|Reactome:R-HSA-5656219|Reactome:R-HSA-8878664 go-plus.json sodium:bicarbonate cotransporter activity|sodium/bicarbonate cotransporter activity http://purl.obolibrary.org/obo/GO_0008510 CHEBI:48980 biolink:ChemicalSubstance quinolin-7-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48980 chebi_ph7_3 CHEBI:48982 biolink:ChemicalSubstance methylquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48982 CHEBI:48981 biolink:ChemicalSubstance quinolin-8-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48981 chebi_ph7_3 CHEBI:58307 biolink:ChemicalSubstance FADH2(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58307 chebi_ph7_3 CHEBI:58306 biolink:ChemicalSubstance rifamycin B(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58306 chebi_ph7_3 CHEBI:58305 biolink:ChemicalSubstance quercetin 3,3'-bissulfate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58305 chebi_ph7_3 CHEBI:58304 biolink:ChemicalSubstance 2-oxo-2H-pyran-4,6-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58304 chebi_ph7_3 CHEBI:58303 biolink:ChemicalSubstance 1-palmitoylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58303 chebi_ph7_3 CHEBI:58302 biolink:ChemicalSubstance UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58302 chebi_ph7_3 PR:000019255 biolink:Protein cholecystokinin proteolytic cleavage product A cholecystokinin that has been processed by proteolytic cleavage. go-plus.json CCK/ClvPrd http://purl.obolibrary.org/obo/PR_000019255 CHEBI:58301 biolink:ChemicalSubstance taurolithocholic acid sulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58301 chebi_ph7_3 CHEBI:73931 biolink:ChemicalSubstance GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73931 chebi_ph7_3 CHEBI:73933 biolink:ChemicalSubstance dTDP-alpha-D-fucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73933 chebi_ph7_3 CHEBI:73932 biolink:ChemicalSubstance GDP-beta-L-colitose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73932 chebi_ph7_3 CHEBI:73935 biolink:ChemicalSubstance 2-chloroacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73935 chebi_ph7_3 CHEBI:73934 biolink:ChemicalSubstance (S)-2-chloropropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73934 chebi_ph7_3 CHEBI:73937 biolink:ChemicalSubstance (3S)-3-hydroxy-L-enduracididine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73937 chebi_ph7_3 CHEBI:73936 biolink:ChemicalSubstance L-enduracididine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73936 chebi_ph7_3 CHEBI:73939 biolink:ChemicalSubstance (3S,5S)-carbapenam-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73939 chebi_ph7_3 CHEBI:73938 biolink:ChemicalSubstance (3S)-3-hydroxy-L-arginine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73938 chebi_ph7_3 PR:000010818 biolink:Protein myogenic factor 5 A protein that is a translation product of the human MYF5 gene or a 1:1 ortholog thereof. go-plus.json Myf-5|MYF5|bHLHc2|class C basic helix-loop-helix protein 2 http://purl.obolibrary.org/obo/PR_000010818 CHEBI:73940 biolink:ChemicalSubstance GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_73940 CHEBI:73943 biolink:ChemicalSubstance (5R)-carbapenem-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73943 chebi_ph7_3 CHEBI:73946 biolink:ChemicalSubstance GDP-beta-L-colitose go-plus.json http://purl.obolibrary.org/obo/CHEBI_73946 GO:0033592 biolink:MolecularActivity RNA strand annealing activity An activity that facilitates the formation of a complementary double-stranded RNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0033592 GO:0033591 biolink:BiologicalProcess response to L-ascorbic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus. go-plus.json response to ascorbic acid|response to L-ascorbate|response to vitamin C http://purl.obolibrary.org/obo/GO_0033591 GO:0033590 biolink:BiologicalProcess response to cobalamin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus. go-plus.json response to vitamin B12 http://purl.obolibrary.org/obo/GO_0033590 GO:0033599 biolink:BiologicalProcess regulation of mammary gland epithelial cell proliferation Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0033599 GO:0033598 biolink:BiologicalProcess mammary gland epithelial cell proliferation The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. go-plus.json http://purl.obolibrary.org/obo/GO_0033598 GO:0033597 biolink:CellularComponent mitotic checkpoint complex A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20. go-plus.json MCC http://purl.obolibrary.org/obo/GO_0033597 GO:0033596 biolink:CellularComponent TSC1-TSC2 complex A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. go-plus.json tuberous sclerosis complex|tuberin-hamartin complex http://purl.obolibrary.org/obo/GO_0033596 GO:0033595 biolink:BiologicalProcess response to genistein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0033595 GO:0033594 biolink:BiologicalProcess response to hydroxyisoflavone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0033594 GO:0033593 biolink:CellularComponent BRCA2-MAGE-D1 complex A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth. go-plus.json http://purl.obolibrary.org/obo/GO_0033593 CHEBI:73950 biolink:ChemicalSubstance dTDP-alpha-D-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_73950 CHEBI:73953 biolink:ChemicalSubstance novobiocic acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73953 chebi_ph7_3 CHEBI:73955 biolink:ChemicalSubstance descarbamoylnovobiocin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73955 chebi_ph7_3 CHEBI:73954 biolink:ChemicalSubstance 8-desmethylnovobiocic acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73954 chebi_ph7_3 CHEBI:73957 biolink:ChemicalSubstance desmethyldescarbamoylnovobiocin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73957 chebi_ph7_3 CHEBI:73956 biolink:ChemicalSubstance (S)-2-chloropropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73956 GO:0033581 biolink:BiologicalProcess protein galactosylation in Golgi The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus. go-plus.json protein amino acid galactosylation in Golgi http://purl.obolibrary.org/obo/GO_0033581 GO:0033580 biolink:BiologicalProcess protein galactosylation at cell surface The addition of a galactose unit to a protein amino acid at the surface of a cell. go-plus.json protein amino acid galactosylation at cell surface http://purl.obolibrary.org/obo/GO_0033580 GO:0033589 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033589 GO:0033588 biolink:CellularComponent elongator holoenzyme complex A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA. go-plus.json Elongator core complex|Elongator holoenzyme complex http://purl.obolibrary.org/obo/GO_0033588 GO:0033587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033587 GO:0033586 biolink:BiologicalProcess L-phenylalanine biosynthetic process from chorismate via L-arogenate The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate. MetaCyc:PWY-3462 go-plus.json L-phenylalanine biosynthesis from chorismate via L-arogenate|L-phenylalanine anabolism from chorismate via L-arogenate|L-phenylalanine synthesis from chorismate via L-arogenate|L-phenylalanine formation from chorismate via L-arogenate http://purl.obolibrary.org/obo/GO_0033586 GO:0033585 biolink:BiologicalProcess L-phenylalanine biosynthetic process from chorismate via phenylpyruvate The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate. MetaCyc:PHESYN go-plus.json L-phenylalanine anabolism from chorismate via phenylpyruvate|L-phenylalanine biosynthesis from chorismate via phenylpyruvate|L-phenylalanine formation from chorismate via phenylpyruvate|L-phenylalanine synthesis from chorismate via phenylpyruvate http://purl.obolibrary.org/obo/GO_0033585 GO:0033584 biolink:BiologicalProcess tyrosine biosynthetic process from chorismate via L-arogenate The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate. MetaCyc:PWY-3461 go-plus.json tyrosine anabolism from chorismate via L-arogenate|tyrosine synthesis from chorismate via L-arogenate|tyrosine formation from chorismate via L-arogenate http://purl.obolibrary.org/obo/GO_0033584 GO:0033583 biolink:CellularComponent rhabdomere membrane The portion of the plasma membrane surrounding the rhabdomere. go-plus.json http://purl.obolibrary.org/obo/GO_0033583 GO:0033582 biolink:BiologicalProcess protein galactosylation in cytosol The addition of a galactose unit to a protein amino acid in the cytosol. go-plus.json protein amino acid galactosylation in cytosol http://purl.obolibrary.org/obo/GO_0033582 CHEBI:73962 biolink:ChemicalSubstance (5S)-5-(carboxymethyl)-L-proline(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73962 chebi_ph7_3 CHEBI:73963 biolink:ChemicalSubstance 2-chloroacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73963 CHEBI:73966 biolink:ChemicalSubstance nitric oxide synthase activator go-plus.json http://purl.obolibrary.org/obo/CHEBI_73966 GO:0033579 biolink:BiologicalProcess protein galactosylation in endoplasmic reticulum The addition of a galactose unit to a protein amino acid in the endoplasmic reticulum. go-plus.json protein amino acid galactosylation in endoplasmic reticulum|protein amino acid galactosylation in ER http://purl.obolibrary.org/obo/GO_0033579 CHEBI:73969 biolink:ChemicalSubstance L-enduracididine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73969 GO:0033570 biolink:MolecularActivity obsolete transferrin transmembrane transporter activity OBSOLETE. Enables the transfer of transferrin from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0033570 GO:0033578 biolink:BiologicalProcess protein glycosylation in Golgi The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. go-plus.json terminal glycosylation|protein amino acid glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0033578 GO:0033577 biolink:BiologicalProcess protein glycosylation in endoplasmic reticulum The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum. go-plus.json core glycosylation|protein amino acid glycosylation in endoplasmic reticulum|protein amino acid glycosylation in ER http://purl.obolibrary.org/obo/GO_0033577 GO:0033576 biolink:BiologicalProcess protein glycosylation in cytosol The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol. go-plus.json protein amino acid glycosylation in cytosol http://purl.obolibrary.org/obo/GO_0033576 GO:0033575 biolink:BiologicalProcess protein glycosylation at cell surface The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell. go-plus.json protein amino acid glycosylation at cell surface http://purl.obolibrary.org/obo/GO_0033575 GO:0033574 biolink:BiologicalProcess response to testosterone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. go-plus.json response to testosterone stimulus http://purl.obolibrary.org/obo/GO_0033574 GO:0033573 biolink:CellularComponent high-affinity iron permease complex A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity iron permease complex http://purl.obolibrary.org/obo/GO_0033573 GO:0033572 biolink:BiologicalProcess transferrin transport The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json melanotransferrin transport http://purl.obolibrary.org/obo/GO_0033572 GO:0033571 biolink:BiologicalProcess lactoferrin transport The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0033571 CHEBI:73973 biolink:ChemicalSubstance beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73973 chebi_ph7_3 CHEBI:73972 biolink:ChemicalSubstance (3S)-3-hydroxy-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73972 CHEBI:73975 biolink:ChemicalSubstance 3-oxo-octacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_73975 CHEBI:73977 biolink:ChemicalSubstance 3-oxotetracosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73977 chebi_ph7_3 CHEBI:73976 biolink:ChemicalSubstance 3-oxo-octacosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73976 chebi_ph7_3 GO:0033569 biolink:MolecularActivity lactoferrin transmembrane transporter activity Enables the transfer of lactoferrin from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0033569 GO:0033568 biolink:MolecularActivity lactoferrin receptor activity Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH. go-plus.json http://purl.obolibrary.org/obo/GO_0033568 CHEBI:73978 biolink:ChemicalSubstance (3S,5S)-carbapenam-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_73978 PR:000010855 biolink:Protein myosin-Ia A protein that is a translation product of the human MYO1A gene or a 1:1 ortholog thereof. go-plus.json MIHC|MYO1A|brush border myosin I|MYHL|BBM-I|myosin I heavy chain|BBMI http://purl.obolibrary.org/obo/PR_000010855 GO:0033567 biolink:BiologicalProcess DNA replication, Okazaki fragment processing The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand. go-plus.json http://purl.obolibrary.org/obo/GO_0033567 GO:0033566 biolink:BiologicalProcess gamma-tubulin complex localization Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location. go-plus.json gamma-tubulin complex localisation|establishment and maintenance of gamma-tubulin complex localization http://purl.obolibrary.org/obo/GO_0033566 GO:0033565 biolink:CellularComponent ESCRT-0 complex A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals. go-plus.json Vps27p-Hse1p complex|Hrs/STAM complex http://purl.obolibrary.org/obo/GO_0033565 GO:0033564 biolink:BiologicalProcess anterior/posterior axon guidance The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. go-plus.json anterior/posterior axon pathfinding|anterior-posterior axon guidance http://purl.obolibrary.org/obo/GO_0033564 GO:0033563 biolink:BiologicalProcess dorsal/ventral axon guidance The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. go-plus.json dorsal-ventral axon guidance|dorsal/ventral axon pathfinding|dorsoventral axon guidance http://purl.obolibrary.org/obo/GO_0033563 GO:0033562 biolink:BiologicalProcess co-transcriptional gene silencing by RNA interference machinery A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin. go-plus.json RNAi-mediated CTGS|cotranscriptional gene silencing by RNA interference machinery|co-transcriptional gene silencing by small RNA|small RNA-mediated cotranscriptional gene silencing|cotranscriptional gene silencing by small RNA http://purl.obolibrary.org/obo/GO_0033562 CHEBI:73971 biolink:ChemicalSubstance (3S)-3-hydroxy-L-enduracididine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73971 GO:0033561 biolink:BiologicalProcess regulation of water loss via skin A process that modulates the rate or extent of water loss from an organism via the skin. go-plus.json skin barrier function http://purl.obolibrary.org/obo/GO_0033561 GO:0033560 biolink:MolecularActivity folate reductase activity Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+. RHEA:31103|Reactome:R-HSA-197963|Reactome:R-HSA-197972 go-plus.json http://purl.obolibrary.org/obo/GO_0033560 CHEBI:73984 biolink:ChemicalSubstance beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73984 chebi_ph7_3 CHEBI:73986 biolink:ChemicalSubstance beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73986 chebi_ph7_3 CHEBI:73988 biolink:ChemicalSubstance beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73988 chebi_ph7_3 GO:0033559 biolink:BiologicalProcess unsaturated fatty acid metabolic process The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms. MetaCyc:PWY-762|MetaCyc:PWY-782 go-plus.json unsaturated fatty acid metabolism http://purl.obolibrary.org/obo/GO_0033559 CHEBI:73987 biolink:ChemicalSubstance alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73987 chebi_ph7_3 GO:0033558 biolink:MolecularActivity protein deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. Reactome:R-HSA-8952069|Reactome:R-HSA-9626962|Reactome:R-HSA-5693092 go-plus.json http://purl.obolibrary.org/obo/GO_0033558 CHEBI:83308 biolink:ChemicalSubstance dioleoylphosphatidate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83308 chebi_ph7_3 GO:0033557 biolink:CellularComponent Slx1-Slx4 complex A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0033557 GO:0033556 biolink:MolecularActivity dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol. go-plus.json dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0033556 GO:0033555 biolink:BiologicalProcess multicellular organismal response to stress Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0033555 GO:0033554 biolink:BiologicalProcess cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). go-plus.json http://purl.obolibrary.org/obo/GO_0033554 gocheck_do_not_manually_annotate GO:0033553 biolink:CellularComponent rDNA heterochromatin A region of heterochromatin located at the rDNA repeats in a chromosome. go-plus.json ribosomal DNA heterochromatin|nuclear rDNA heterochromatin|ribosomal DNA heterochromatin of cell nucleus|ribosomal DNA heterochromatin of nucleus http://purl.obolibrary.org/obo/GO_0033553 GO:0033552 biolink:BiologicalProcess response to vitamin B3 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus. go-plus.json response to nicotinamide|response to niacin http://purl.obolibrary.org/obo/GO_0033552 CHEBI:73980 biolink:ChemicalSubstance 3-oxohexacosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73980 chebi_ph7_3 GO:0033551 biolink:CellularComponent monopolin complex A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits. go-plus.json monopolin subcomplex Csm1/Lrs4|Pcs1/Mde4 complex http://purl.obolibrary.org/obo/GO_0033551 GO:0033550 biolink:MolecularActivity MAP kinase tyrosine phosphatase activity Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate. go-plus.json tyrosine-specific MAP kinase phosphatase activity http://purl.obolibrary.org/obo/GO_0033550 CHEBI:73995 biolink:ChemicalSubstance 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_73995 chebi_ph7_3 CHEBI:73997 biolink:ChemicalSubstance GDP-N-acetyl-alpha-D-perosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73997 chebi_ph7_3 CHEBI:73996 biolink:ChemicalSubstance GDP-4-amino-4,6-dideoxy-alpha-D-mannose(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73996 chebi_ph7_3 GO:0033549 biolink:MolecularActivity MAP kinase phosphatase activity Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate. go-plus.json MAPK phosphatase activity http://purl.obolibrary.org/obo/GO_0033549 CHEBI:73999 biolink:ChemicalSubstance 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_73999 chebi_ph7_3 GO:0033548 biolink:BiologicalProcess myo-inositol hexakisphosphate biosynthetic process, lipid-independent The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate. MetaCyc:PWY-4661 go-plus.json myo-inositol hexakisphosphate synthesis, lipid-independent|myo-inositol hexakisphosphate anabolism, lipid-independent|phytate biosynthesis, lipid-independent|phytate biosynthetic process, lipid-independent|myo-inositol hexakisphosphate biosynthesis, lipid-independent|myo-inositol hexakisphosphate formation, lipid-independent http://purl.obolibrary.org/obo/GO_0033548 CHEBI:73998 biolink:ChemicalSubstance 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73998 chebi_ph7_3 GO:0033547 biolink:BiologicalProcess obsolete myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate OBSOLETE. The chemical reactions and pathways resulting in the formation of 1D myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is successively phosphorylated to yield inositol hexakisphosphate. MetaCyc:PWY-4541 go-plus.json myo-inositol hexakisphosphate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate anabolism, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate synthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate formation, via direct phosphorylation of inositol 1,4,5-trisphosphate http://purl.obolibrary.org/obo/GO_0033547 GO:0033546 biolink:BiologicalProcess myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further. MetaCyc:PWY-6554 go-plus.json myo-inositol hexakisphosphate biosynthesis, via inositol 1,3,4-trisphosphate|phytate biosynthetic process, via inositol 1,3,4-trisphosphate|phytate biosynthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate anabolism, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate synthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate formation, via inositol 1,3,4-trisphosphate http://purl.obolibrary.org/obo/GO_0033546 GO:0008589 biolink:BiologicalProcess regulation of smoothened signaling pathway Any process that modulates the frequency, rate or extent of smoothened signaling. go-plus.json regulation of smoothened by patched|regulation of hh signaling pathway|regulation of hedgehog signaling pathway|regulation of smoothened activity|regulation of smoothened signalling pathway|regulation of smoothened receptor activity by patched http://purl.obolibrary.org/obo/GO_0008589 GO:0008588 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008588 CHEBI:83317 biolink:ChemicalSubstance sterol biosynthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_83317 GO:0008587 biolink:BiologicalProcess imaginal disc-derived wing margin morphogenesis The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade. go-plus.json wing margin morphogenesis http://purl.obolibrary.org/obo/GO_0008587 GO:0008586 biolink:BiologicalProcess imaginal disc-derived wing vein morphogenesis The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized. go-plus.json wing vein morphogenesis http://purl.obolibrary.org/obo/GO_0008586 GO:0008585 biolink:BiologicalProcess female gonad development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. go-plus.json ovary development|ovarian development http://purl.obolibrary.org/obo/GO_0008585 GO:0008584 biolink:BiologicalProcess male gonad development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. go-plus.json testis development|testicular development http://purl.obolibrary.org/obo/GO_0008584 GO:0008583 biolink:BiologicalProcess mystery cell differentiation The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0008583 GO:0008582 biolink:BiologicalProcess regulation of synaptic assembly at neuromuscular junction Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions. go-plus.json regulation of synaptic growth at neuromuscular junction http://purl.obolibrary.org/obo/GO_0008582 GO:0008592 biolink:BiologicalProcess regulation of Toll signaling pathway Any process that modulates the frequency, rate or extent of the Tl signaling pathway. go-plus.json regulation of Tl signalling pathway|regulation of Toll signalling pathway|regulation of Tl signaling pathway http://purl.obolibrary.org/obo/GO_0008592 CHEBI:58398 biolink:ChemicalSubstance (2S)-2-hydroxyphytanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58398 chebi_ph7_3 GO:0008591 biolink:BiologicalProcess regulation of Wnt signaling pathway, calcium modulating pathway Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). go-plus.json regulation of Wnt receptor signaling pathway, calcium modulating pathway|regulation of Wnt-activated signaling pathway, calcium modulating pathway|regulation of frizzled-2 signaling pathway|regulation of frizzled-2 signalling pathway http://purl.obolibrary.org/obo/GO_0008591 GO:0008590 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008590 CHEBI:58396 biolink:ChemicalSubstance aerobactinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58396 chebi_ph7_3 CHEBI:58395 biolink:ChemicalSubstance myricetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58395 chebi_ph7_3 CHEBI:58394 biolink:ChemicalSubstance 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58394 chebi_ph7_3 CHEBI:58393 biolink:ChemicalSubstance aureusidin-6-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58393 CHEBI:58392 biolink:ChemicalSubstance alpha-D-glucose 1,6-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58392 chebi_ph7_3 CHEBI:58391 biolink:ChemicalSubstance all-trans-nonaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58391 chebi_ph7_3 NCBITaxon:200643 biolink:OrganismalEntity Bacteroidia go-plus.json Bacteroidetes http://purl.obolibrary.org/obo/NCBITaxon_200643 GO:0033545 biolink:BiologicalProcess myo-inositol hexakisphosphate biosynthetic process, lipid-dependent The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C. MetaCyc:PWY-6555 go-plus.json phytate biosynthesis, lipid-dependent|phytate biosynthetic process, lipid-dependent|myo-inositol hexakisphosphate biosynthesis, lipid-dependent|myo-inositol hexakisphosphate formation, lipid-dependent|myo-inositol hexakisphosphate synthesis, lipid-dependent|myo-inositol hexakisphosphate anabolism, lipid-dependent http://purl.obolibrary.org/obo/GO_0033545 GO:0033544 biolink:BiologicalProcess fatty acid beta-oxidation, unsaturated, even number, epimerase pathway A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). go-plus.json http://purl.obolibrary.org/obo/GO_0033544 GO:0033543 biolink:BiologicalProcess fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). go-plus.json http://purl.obolibrary.org/obo/GO_0033543 GO:0033542 biolink:BiologicalProcess fatty acid beta-oxidation, unsaturated, even number A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). MetaCyc:PWY-5138 go-plus.json http://purl.obolibrary.org/obo/GO_0033542 CHEBI:73991 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73991 chebi_ph7_3 GO:0033541 biolink:BiologicalProcess fatty acid beta-oxidation, unsaturated, odd number A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). MetaCyc:PWY-5137 go-plus.json http://purl.obolibrary.org/obo/GO_0033541 CHEBI:73990 biolink:ChemicalSubstance 2-oleoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_73990 chebi_ph7_3 GO:0033540 biolink:BiologicalProcess fatty acid beta-oxidation using acyl-CoA oxidase A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). MetaCyc:PWY-5136 go-plus.json http://purl.obolibrary.org/obo/GO_0033540 CHEBI:73993 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73993 chebi_ph7_3 CHEBI:58399 biolink:ChemicalSubstance isopenicillin N(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58399 chebi_ph7_3 GO:0033539 biolink:BiologicalProcess fatty acid beta-oxidation using acyl-CoA dehydrogenase A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). MetaCyc:FAO-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0033539 GO:0033538 biolink:BiologicalProcess ajugose biosynthetic process using galactan:galactan galactosyltransferase The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another. MetaCyc:PWY-5343 go-plus.json ajugose anabolism using galactan:galactan galactosyltransferase|ajugose synthesis using galactan:galactan galactosyltransferase|ajugose formation using galactan:galactan galactosyltransferase|ajugose biosynthesis using galactan:galactan galactosyltransferase http://purl.obolibrary.org/obo/GO_0033538 CHEBI:128459 biolink:ChemicalSubstance valienol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_128459 GO:0033537 biolink:BiologicalProcess ajugose biosynthetic process using galactinol:raffinose galactosyltransferase The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide. MetaCyc:PWY-5342 go-plus.json ajugose formation using galactinol:raffinose galactosyltransferase|ajugose synthesis using galactinol:raffinose galactosyltransferase|ajugose anabolism using galactinol:raffinose galactosyltransferase|ajugose biosynthesis using galactinol:raffinose galactosyltransferase http://purl.obolibrary.org/obo/GO_0033537 GO:0033536 biolink:BiologicalProcess ajugose biosynthetic process The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json ajugose biosynthesis|ajugose anabolism|ajugose synthesis|ajugose formation http://purl.obolibrary.org/obo/GO_0033536 GO:0033535 biolink:BiologicalProcess ajugose metabolic process The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json ajugose metabolism http://purl.obolibrary.org/obo/GO_0033535 CHEBI:58390 biolink:ChemicalSubstance N(6')-acetylkanamycin B(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58390 chebi_ph7_3 GO:0008599 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008599 GO:0008598 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008598 GO:0008597 biolink:MolecularActivity calcium-dependent protein serine/threonine phosphatase regulator activity Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase. Reactome:R-HSA-139906 go-plus.json calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0008597 GO:0008596 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008596 GO:0008595 biolink:BiologicalProcess anterior/posterior axis specification, embryo The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote. go-plus.json anterior/posterior axis determination, embryo http://purl.obolibrary.org/obo/GO_0008595 CHEBI:83324 biolink:ChemicalSubstance pent-2-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83324 chebi_ph7_3 GO:0008594 biolink:BiologicalProcess photoreceptor cell morphogenesis The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. go-plus.json photoreceptor development http://purl.obolibrary.org/obo/GO_0008594 GO:0008593 biolink:BiologicalProcess regulation of Notch signaling pathway Any process that modulates the frequency, rate or extent of the Notch signaling pathway. go-plus.json regulation of N signaling pathway|regulation of N signalling pathway|regulation of Notch signalling pathway http://purl.obolibrary.org/obo/GO_0008593 CHEBI:58387 biolink:ChemicalSubstance 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58387 chebi_ph7_3 CHEBI:58386 biolink:ChemicalSubstance (S)-2-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58386 chebi_ph7_3 CHEBI:58385 biolink:ChemicalSubstance luteolin 7-O-beta-D-glucosiduronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58385 CHEBI:58384 biolink:ChemicalSubstance cadaverine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58384 chebi_ph7_3 CHEBI:58383 biolink:ChemicalSubstance phosphonoacetaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58383 chebi_ph7_3 CHEBI:58382 biolink:ChemicalSubstance 5-ammoniopentanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_58382 chebi_ph7_3 CHEBI:58381 biolink:ChemicalSubstance 3-ADP-2-phosphoglycerate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58381 chebi_ph7_3 CHEBI:58380 biolink:ChemicalSubstance pseudouridine 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58380 chebi_ph7_3 GO:0033534 biolink:BiologicalProcess verbascose biosynthetic process The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json verbascose anabolism|verbascose synthesis|verbascose formation|verbascose biosynthesis http://purl.obolibrary.org/obo/GO_0033534 GO:0033533 biolink:BiologicalProcess verbascose metabolic process The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json verbascose metabolism http://purl.obolibrary.org/obo/GO_0033533 GO:0033532 biolink:BiologicalProcess stachyose biosynthetic process The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. MetaCyc:PWY-5337 go-plus.json stachyose anabolism|stachyose synthesis|stachyose biosynthesis|stachyose formation http://purl.obolibrary.org/obo/GO_0033532 GO:0033531 biolink:BiologicalProcess stachyose metabolic process The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json stachyose metabolism http://purl.obolibrary.org/obo/GO_0033531 GO:0033530 biolink:BiologicalProcess raffinose metabolic process The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. go-plus.json raffinose metabolism http://purl.obolibrary.org/obo/GO_0033530 CHEBI:58389 biolink:ChemicalSubstance trimethylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58389 chebi_ph7_3 CHEBI:58388 biolink:ChemicalSubstance heparan sulfate alpha-D-glucosaminide polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58388 chebi_ph7_3 CHEBI:24922 biolink:ChemicalSubstance isoquinolines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24922 CHEBI:24921 biolink:ChemicalSubstance isoquinoline alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24921 CHEBI:24923 biolink:ChemicalSubstance isoquinolinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24923 CHEBI:24928 biolink:ChemicalSubstance isothiocyanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24928 chebi_ph7_3 CHEBI:24937 biolink:ChemicalSubstance jasmonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_24937 CHEBI:24909 biolink:ChemicalSubstance hydrocarbyladenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24909 CHEBI:24911 biolink:ChemicalSubstance isopiperitenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24911 chebi_ph7_3 CHEBI:24913 biolink:ChemicalSubstance isoprenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24913 CHEBI:2533 biolink:ChemicalSubstance alachlor go-plus.json http://purl.obolibrary.org/obo/CHEBI_2533 chebi_ph7_3 CHEBI:73913 biolink:ChemicalSubstance antifolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_73913 CHEBI:2519 biolink:ChemicalSubstance agroclavine go-plus.json http://purl.obolibrary.org/obo/CHEBI_2519 GO:0033493 biolink:BiologicalProcess esculetin biosynthetic process The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin. MetaCyc:PWY-5349 go-plus.json esculetin biosynthesis|esculetin anabolism|esculetin synthesis|esculetin formation http://purl.obolibrary.org/obo/GO_0033493 GO:0033492 biolink:BiologicalProcess esculetin metabolic process The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin. go-plus.json esculetin metabolism http://purl.obolibrary.org/obo/GO_0033492 GO:0033491 biolink:BiologicalProcess coniferin metabolic process The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside. MetaCyc:PWY-116 go-plus.json coniferin metabolism http://purl.obolibrary.org/obo/GO_0033491 GO:0033490 biolink:BiologicalProcess cholesterol biosynthetic process via lathosterol The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol. MetaCyc:PWY66-341 go-plus.json cholesterol anabolism via lathosterol|cholesterol synthesis via lathosterol|cholesterol formation via lathosterol|cholesterol biosynthesis via lathosterol http://purl.obolibrary.org/obo/GO_0033490 GO:0033499 biolink:BiologicalProcess galactose catabolic process via UDP-galactose The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose. MetaCyc:PWY-3821 go-plus.json galactose catabolism via UDP-galactose|galactose degradation via UDP-galactose|galactose breakdown via UDP-galactose|Leloir Pathway http://purl.obolibrary.org/obo/GO_0033499 GO:0033498 biolink:BiologicalProcess galactose catabolic process via D-galactonate The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate. MetaCyc:GALDEG-PWY go-plus.json galactose catabolism via D-galactonate|galactose degradation via D-galactonate|galactose breakdown via D-galactonate http://purl.obolibrary.org/obo/GO_0033498 GO:0033497 biolink:BiologicalProcess sinapate biosynthetic process The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. MetaCyc:PWY-5168 go-plus.json sinapate anabolism|sinapate biosynthesis|sinapate synthesis|sinapate formation http://purl.obolibrary.org/obo/GO_0033497 GO:0033496 biolink:BiologicalProcess sinapate metabolic process The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. go-plus.json sinapate metabolism http://purl.obolibrary.org/obo/GO_0033496 GO:0033495 biolink:BiologicalProcess ferulate biosynthetic process The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate. MetaCyc:PWY-5168 go-plus.json ferulate biosynthesis|ferulate anabolism|ferulate synthesis|ferulate formation http://purl.obolibrary.org/obo/GO_0033495 GO:0033494 biolink:BiologicalProcess ferulate metabolic process The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate. go-plus.json ferulate metabolism http://purl.obolibrary.org/obo/GO_0033494 CHEBI:48975 biolink:ChemicalSubstance substituted aniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_48975 CHEBI:10359 biolink:ChemicalSubstance (-)-beta-chamigrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10359 chebi_ph7_3 UBERON:0005992 biolink:AnatomicalEntity pulmonary valve cusp The three fibrous triangular components and associated flap of the pulmonary valve go-plus.json pulmonary valvular cusp|semilunar valvule of pulmonary valve|pulmonary semilunar valvule|semilunar cusp of pulmonary valve|cusp of pulmonary valve http://purl.obolibrary.org/obo/UBERON_0005992 UBERON:0005991 biolink:AnatomicalEntity aortic valve anulus The fibrous ring of the aortic valve that attaches the cusps of aortic valve to the wall of left ventricle, and which consists of portions of the fibrous scallops of the posterior, right anterior and left anterior cusps go-plus.json aortic valvar anulus|anulus of aortic valve|fibrous ring of aortic valve|aortic anulus http://purl.obolibrary.org/obo/UBERON_0005991 UBERON:0005990 biolink:AnatomicalEntity aortic valve cusp The three fibrous triangular components and associated flap of the aortic valve go-plus.json cusp of aortic valve|aortic semilunar valvule|semilunar valvule of aortic valve|aortic valvular cusp http://purl.obolibrary.org/obo/UBERON_0005990 CHEBI:10352 biolink:ChemicalSubstance beta-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_10352 chebi_ph7_3 CHEBI:10357 biolink:ChemicalSubstance (-)-beta-caryophyllene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10357 chebi_ph7_3 CHEBI:83290 biolink:ChemicalSubstance N(alpha)-(L-gamma-glutamyl)-hercynyl-L-cysteine sulfoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_83290 UBERON:0005998 biolink:AnatomicalEntity tricuspid valve cusp The three fibrous triangular components and associated flaps of the tricuspid valve go-plus.json septal leaflet of right-sided tricuspid valve|cuspis septalis valvae atrioventricularis dextrae|septal tricuspid leaflet|septal cusp of tricuspid valve|cuspis septalis (valva tricuspidalis)|septal cusp of right atrioventricular valve|septal leaflet of tricuspid valve http://purl.obolibrary.org/obo/UBERON_0005998 UBERON:0005997 biolink:AnatomicalEntity tricuspid valve anulus The fibrous ring of the tricuspid valve that attaches the cusps of tricuspid valve to the heart, and which consists of portions of the fibrous scallops of the anterior cusp (infundibular cusp), the posterior cusp (marginal cusp), and the septal cusp (medial cusp) go-plus.json tricuspid valvar anulus|tricuspid anulus|fibrous ring of tricuspid valve|anulus of tricuspid valve http://purl.obolibrary.org/obo/UBERON_0005997 UBERON:0005996 biolink:AnatomicalEntity mitral valve cusp The two fibrous components and associated flaps of the mitral valve go-plus.json http://purl.obolibrary.org/obo/UBERON_0005996 CHEBI:2571 biolink:ChemicalSubstance aliphatic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_2571 chebi_ph7_3 UBERON:0005995 biolink:AnatomicalEntity mitral valve anulus The fibrous ring of the mitral valve that attaches the cusps of mitral valve to the heart, and which consists of portions of the fibrous scallops of the anterior and posterior cusps go-plus.json fibrous ring of mitral valve|mitral valvar anulus|anulus of mitral valve|mitral anulus|mitral annulus http://purl.obolibrary.org/obo/UBERON_0005995 UBERON:0005994 biolink:AnatomicalEntity chorda tendineae The tendinous strands that connect the papillary muscles on the wall of the ventricles to the leaflets of the atrioventricular valves; the chordae tendineae serve to prevent the AV valves from prolapsing back into the atria go-plus.json chordae tendineae cordis|chordae tendinea http://purl.obolibrary.org/obo/UBERON_0005994 UBERON:0005993 biolink:AnatomicalEntity pulmonary valve anulus The fibrous ring of the pulmonary valve that attaches the cusps of pulmonary valve to the wall of right ventricle, and which consists of portions of the fibrous scallops of the anterior, right posterior and left posterior cusps go-plus.json fibrous ring of pulmonary valve|anulus of pulmonary valve|pulmonary anulus|pulmonary valvar anulus http://purl.obolibrary.org/obo/UBERON_0005993 CHEBI:48965 biolink:ChemicalSubstance trans-chalcone go-plus.json http://purl.obolibrary.org/obo/CHEBI_48965 chebi_ph7_3 CHEBI:48968 biolink:ChemicalSubstance (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48968 NCBITaxon:31181 biolink:OrganismalEntity Strongylocentrotidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_31181 UBERON:0005979 biolink:AnatomicalEntity crista terminalis The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium go-plus.json crista terminalis atrii dextri|crista terminalis of right atrium|crista terminalis cordis http://purl.obolibrary.org/obo/UBERON_0005979 CHEBI:2588 biolink:ChemicalSubstance Alkylated DNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_2588 PR:000020180 biolink:Protein haptoglobin proteolytic cleavage product A haptoglobin that has been processed by proteolytic cleavage. go-plus.json HP/ClvPrd http://purl.obolibrary.org/obo/PR_000020180 UBERON:0005989 biolink:AnatomicalEntity atrioventricular septum The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve go-plus.json membranous atrioventricular septum http://purl.obolibrary.org/obo/UBERON_0005989 UBERON:0005988 biolink:AnatomicalEntity atrium myocardial trabecula The supporting bundles of muscular fibers lining the walls of the atrial myocardium go-plus.json atrial trabecula|trabecular layer of atrium|atrium myocardial trabeculae|trabecula of atrium|trabecular layer of the atrium http://purl.obolibrary.org/obo/UBERON_0005988 CHEBI:48969 biolink:ChemicalSubstance (2R,3R)-2,3-dihydroxy-2,3-dihydrobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48969 CHEBI:2580 biolink:ChemicalSubstance unsaturated fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_2580 OIO:hasNarrowSynonym biolink:OntologyClass has_narrow_synonym go-plus.json http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym UBERON:0005985 biolink:AnatomicalEntity coronary vessel Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation go-plus.json http://purl.obolibrary.org/obo/UBERON_0005985 UBERON:0005983 biolink:AnatomicalEntity heart layer The laminar structure of the heart go-plus.json http://purl.obolibrary.org/obo/UBERON_0005983 CHEBI:48951 biolink:ChemicalSubstance cyclohexenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_48951 CHEBI:48950 biolink:ChemicalSubstance L-2,4-diaminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48950 CHEBI:24983 biolink:ChemicalSubstance ketoxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_24983 chebi_ph7_3 CHEBI:48953 biolink:ChemicalSubstance cyclohexenones go-plus.json http://purl.obolibrary.org/obo/CHEBI_48953 CHEBI:24982 biolink:ChemicalSubstance ketotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24982 CHEBI:24981 biolink:ChemicalSubstance ketotetrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24981 CHEBI:48954 biolink:ChemicalSubstance 7,8-dihydroneopterin 3'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48954 UBERON:0005969 biolink:AnatomicalEntity eye trabecular meshwork A pore-like structure surrounding the entire circumference of the anterior chamber of the eye through which aqueous humor circulates[MP]. go-plus.json scleral trabecular|cribiform ligament|eye trabecular meshwork|reticulum trabeculare|pectinate ligament|iridis|pectinate ligament of iris|ligamentum pectinatum|Hueck's ligament|trabecular mesh|ligamentum pectinatum iridis|scleral trabecule|trabecular meshwork of the eye|scleral trabeculae|scribiform ligament|ligamentum peactin-tum iridis|trabecular meshwork|ligamentum pectinatum anguli iridocornealis|reticulum trabeculare sclerae http://purl.obolibrary.org/obo/UBERON_0005969 CHEBI:48957 biolink:ChemicalSubstance N(2)-succinyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48957 CHEBI:48956 biolink:ChemicalSubstance 5-O-phosphono-D-ribofuranosyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48956 CHEBI:34306 biolink:ChemicalSubstance 20-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_34306 CHEBI:24980 biolink:ChemicalSubstance ketotetrose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24980 UBERON:0005970 biolink:AnatomicalEntity brain commissure any of the nerve fiber tracts that span the longitudinal fissure between the cerebral and/or cerebellar hemispheres of the brain go-plus.json http://purl.obolibrary.org/obo/UBERON_0005970 CHEBI:2559 biolink:ChemicalSubstance aldohexose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_2559 CHEBI:48959 biolink:ChemicalSubstance monoazo compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_48959 CHEBI:48958 biolink:ChemicalSubstance 1,1'-azobis(N,N-dimethylformamide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48958 chebi_ph7_3 UBERON:0005971 biolink:AnatomicalEntity amniotic fold A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]. go-plus.json amnionic fold http://purl.obolibrary.org/obo/UBERON_0005971 CHEBI:24995 biolink:ChemicalSubstance lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_24995 CHEBI:48940 biolink:ChemicalSubstance (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_48940 chebi_ph7_3 CHEBI:48942 biolink:ChemicalSubstance isovalerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48942 chebi_ph7_3 CHEBI:48944 biolink:ChemicalSubstance isobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48944 chebi_ph7_3 CHEBI:48943 biolink:ChemicalSubstance isobutyraldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_48943 chebi_ph7_3 CHEBI:48946 biolink:ChemicalSubstance 2-methylbutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48946 chebi_ph7_3 CHEBI:24996 biolink:ChemicalSubstance lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24996 chebi_ph7_3 CHEBI:34317 biolink:ChemicalSubstance 3,3',4,4',5-pentachlorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_34317 chebi_ph7_3 CHEBI:24990 biolink:ChemicalSubstance kynurenamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24990 CHEBI:34310 biolink:ChemicalSubstance (24S)-24-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34310 chebi_ph7_3 CHEBI:10365 biolink:ChemicalSubstance (5S)-3-acetyl-4-hydroxy-5-{[4-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}-1,5-dihydro-2H-pyrrol-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_10365 CHEBI:10363 biolink:ChemicalSubstance beta-cubebene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10363 chebi_ph7_3 CHEBI:34311 biolink:ChemicalSubstance 27-O-demethylrifamycin SV go-plus.json http://purl.obolibrary.org/obo/CHEBI_34311 CHEBI:10362 biolink:ChemicalSubstance beta-cryptoxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_10362 chebi_ph7_3 CHEBI:48948 biolink:ChemicalSubstance demethylsulochrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48948 UBERON:0005966 biolink:AnatomicalEntity outflow part of left atrium An outflow tract of atrium that is part of a left atrium. go-plus.json outflow tract of left atrium|main part of left atrium http://purl.obolibrary.org/obo/UBERON_0005966 CHEBI:48947 biolink:ChemicalSubstance clavulanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48947 UBERON:0005965 biolink:AnatomicalEntity outflow part of right atrium Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA] go-plus.json main part of right atrium|outflow tract of right atrium http://purl.obolibrary.org/obo/UBERON_0005965 CHEBI:48949 biolink:ChemicalSubstance 3-phenylcyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48949 chebi_ph7_3 CHEBI:24962 biolink:ChemicalSubstance ketoaldonic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24962 CHEBI:24961 biolink:ChemicalSubstance ketoaldonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24961 CHEBI:24960 biolink:ChemicalSubstance ketoaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_24960 CHEBI:48931 biolink:ChemicalSubstance (2S,3R)-3-carboxy-2,3-dihydroxypropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48931 CHEBI:48930 biolink:ChemicalSubstance (2R,3S)-3-carboxy-2,3-dihydroxypropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48930 CHEBI:24966 biolink:ChemicalSubstance keto-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24966 CHEBI:48932 biolink:ChemicalSubstance L-glyceraldehyde 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48932 CHEBI:24965 biolink:ChemicalSubstance deoxyketohexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24965 CHEBI:24964 biolink:ChemicalSubstance deoxyketohexose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24964 CHEBI:24963 biolink:ChemicalSubstance ketoaldonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24963 CHEBI:48937 biolink:ChemicalSubstance phytane go-plus.json http://purl.obolibrary.org/obo/CHEBI_48937 chebi_ph7_3 CHEBI:48939 biolink:ChemicalSubstance (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_48939 chebi_ph7_3 CHEBI:24967 biolink:ChemicalSubstance ketogluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24967 CHEBI:24973 biolink:ChemicalSubstance ketohexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24973 CHEBI:24972 biolink:ChemicalSubstance ketohexose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24972 CHEBI:24971 biolink:ChemicalSubstance ketohexose monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24971 CHEBI:24970 biolink:ChemicalSubstance ketohexose bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24970 CHEBI:24977 biolink:ChemicalSubstance ketopentose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24977 CHEBI:24976 biolink:ChemicalSubstance ketopentose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24976 CHEBI:24975 biolink:ChemicalSubstance ketooctose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24975 CHEBI:48923 biolink:ChemicalSubstance erythromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48923 CHEBI:48926 biolink:ChemicalSubstance S-(hydroxymethyl)glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_48926 CHEBI:48928 biolink:ChemicalSubstance 6-phospho-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48928 CHEBI:48927 biolink:ChemicalSubstance N-acyl-L-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48927 CHEBI:24978 biolink:ChemicalSubstance ketose go-plus.json http://purl.obolibrary.org/obo/CHEBI_24978 CHEBI:48929 biolink:ChemicalSubstance 3-carboxy-2,3-dihydroxypropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48929 CHEBI:24943 biolink:ChemicalSubstance juvenile hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_24943 CHEBI:2596 biolink:ChemicalSubstance alliin go-plus.json http://purl.obolibrary.org/obo/CHEBI_2596 UBERON:0015329 biolink:AnatomicalEntity respiratory system basement membrane A basement membrane of epithelium that is part of a respiratory system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015329 CHEBI:10334 biolink:ChemicalSubstance alpha-terpinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10334 chebi_ph7_3 CHEBI:48914 biolink:ChemicalSubstance glucaric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_48914 CHEBI:48916 biolink:ChemicalSubstance altraric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_48916 CHEBI:24951 biolink:ChemicalSubstance kanamycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_24951 CHEBI:48901 biolink:ChemicalSubstance thiazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_48901 CHEBI:10329 biolink:ChemicalSubstance alpha-ribazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_10329 chebi_ph7_3 CHEBI:24957 biolink:ChemicalSubstance keto-disaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24957 CHEBI:48905 biolink:ChemicalSubstance (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48905 CHEBI:48907 biolink:ChemicalSubstance (9Z,11E,15Z)-octadeca-9,11,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48907 CHEBI:73898 biolink:ChemicalSubstance Gly-Gln go-plus.json http://purl.obolibrary.org/obo/CHEBI_73898 GO:0033649 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033649 GO:0033648 biolink:CellularComponent host intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json host intracellular membrane-enclosed organelle http://purl.obolibrary.org/obo/GO_0033648 GO:0033647 biolink:CellularComponent host intracellular organelle Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033647 GO:0033646 biolink:CellularComponent host intracellular part Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json host cell intracellular part http://purl.obolibrary.org/obo/GO_0033646 gocheck_do_not_annotate GO:0008689 biolink:MolecularActivity 3-demethylubiquinone-9 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9. RHEA:17049|MetaCyc:DHHB-METHYLTRANSFER-RXN|EC:2.1.1.64 go-plus.json S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity|5-demethylubiquinone-9 methyltransferase activity|S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity|OMHMB-methyltransferase activity http://purl.obolibrary.org/obo/GO_0008689 GO:0033645 biolink:CellularComponent host cell endomembrane system A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033645 GO:0008688 biolink:MolecularActivity 3-(3-hydroxyphenyl)propionate hydroxylase activity Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O. EC:1.14.13.127|RHEA:24785|KEGG_REACTION:R06786|MetaCyc:MHPHYDROXY-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008688 GO:0008687 biolink:MolecularActivity 3,4-dihydroxyphenylacetate 2,3-dioxygenase activity Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+). EC:1.13.11.15|MetaCyc:1.13.11.15-RXN|KEGG_REACTION:R03303|UM-BBD_reactionID:r0364|RHEA:15633 go-plus.json 3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity|HPC dioxygenase activity|homoprotocatechuate 2,3-dioxygenase activity|3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0008687 GO:0008686 biolink:MolecularActivity 3,4-dihydroxy-2-butanone-4-phosphate synthase activity Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). RHEA:18457|KEGG_REACTION:R07281|EC:4.1.99.12|MetaCyc:DIOHBUTANONEPSYN-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008686 GO:0008685 biolink:MolecularActivity 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP. MetaCyc:RXN0-302|KEGG_REACTION:R05637|RHEA:23864|EC:4.6.1.12 go-plus.json MECDP-synthase activity|MECP synthase activity|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming) http://purl.obolibrary.org/obo/GO_0008685 GO:0008684 biolink:MolecularActivity 2-oxopent-4-enoate hydratase activity Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O. RHEA:22580|UM-BBD_enzymeID:e0078|MetaCyc:2-OXOPENT-4-ENOATE-HYDRATASE-RXN|EC:4.2.1.80 go-plus.json OEH activity|4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)|2-keto-4-pentenoate hydratase activity|2-keto-4-pentenoate (vinylpyruvate)hydratase activity|4-hydroxy-2-oxopentanoate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0008684 GO:0008683 biolink:MolecularActivity 2-oxoglutarate decarboxylase activity Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde. MetaCyc:RXN-7774|RHEA:10524|EC:4.1.1.71|KEGG_REACTION:R00272 go-plus.json 2-oxoglutarate carboxy-lyase activity|2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)|alpha-ketoglutaric decarboxylase activity|alpha-ketoglutarate decarboxylase activity|pre-2-oxoglutarate decarboxylase activity http://purl.obolibrary.org/obo/GO_0008683 GO:0008682 biolink:MolecularActivity 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone. RHEA:50908|EC:1.14.99.60|MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN go-plus.json demethoxyubiquinone monooxygenase|demethoxy-ubiquinone hydroxylase http://purl.obolibrary.org/obo/GO_0008682 GO:0008681 biolink:MolecularActivity 2-octaprenyl-6-methoxyphenol hydroxylase activity Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O. RHEA:29407|MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0008681 GO:0008691 biolink:MolecularActivity 3-hydroxybutyryl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+. MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN|RHEA:16197|EC:1.1.1.157 go-plus.json BHBD activity|beta-hydroxybutyryl-CoA dehydrogenase activity|L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity|(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity|dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)|L(+)-3-hydroxybutyryl-CoA dehydrogenase activity|beta-hydroxybutyryl coenzyme A dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008691 CHEBI:58255 biolink:ChemicalSubstance aldehydo-D-galactose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58255 chebi_ph7_3 CHEBI:83211 biolink:ChemicalSubstance tirucallane triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83211 GO:0008690 biolink:MolecularActivity 3-deoxy-manno-octulosonate cytidylyltransferase activity Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate. RHEA:23448|EC:2.7.7.38|MetaCyc:CPM-KDOSYNTH-RXN go-plus.json 2-keto-3-deoxyoctonate cytidylyltransferase activity|3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CMP-2-keto-3-deoxyoctulosonic acid synthetase activity|CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity|CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity|CMP-3-deoxy-D-manno-octulosonate synthetase activity|CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity|CMP-KDO synthetase activity|CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity|cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0008690 CHEBI:58254 biolink:ChemicalSubstance quercetin 3-sulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58254 chebi_ph7_3 CHEBI:58253 biolink:ChemicalSubstance (S)-norcoclaurinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58253 chebi_ph7_3 CHEBI:58252 biolink:ChemicalSubstance S-methyl-L-methionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58252 chebi_ph7_3 CHEBI:58251 biolink:ChemicalSubstance N,N-dimethylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58251 chebi_ph7_3 GO:0018007 biolink:BiologicalProcess N-terminal peptidyl-glycine N-glucuronylation The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine. RESID:AA0058 go-plus.json http://purl.obolibrary.org/obo/GO_0018007 GO:0018006 biolink:BiologicalProcess N-terminal protein amino acid glucuronylation The glucuronylation of the N-terminal amino acid of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0018006 GO:0018009 biolink:BiologicalProcess N-terminal peptidyl-L-cysteine N-palmitoylation The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine. RESID:AA0060 go-plus.json http://purl.obolibrary.org/obo/GO_0018009 GO:0018008 biolink:BiologicalProcess N-terminal peptidyl-glycine N-myristoylation The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine. RESID:AA0059 go-plus.json N-terminal peptidyl-glycine N-myristylation http://purl.obolibrary.org/obo/GO_0018008 GO:0018003 biolink:BiologicalProcess peptidyl-lysine N6-acetylation The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine. RESID:AA0055 go-plus.json http://purl.obolibrary.org/obo/GO_0018003 GO:0033644 biolink:CellularComponent host cell membrane Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033644 GO:0018002 biolink:BiologicalProcess N-terminal peptidyl-glutamic acid acetylation The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid. RESID:AA0044 go-plus.json http://purl.obolibrary.org/obo/GO_0018002 GO:0033643 biolink:CellularComponent host cell part Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033643 gocheck_do_not_annotate GO:0033642 biolink:BiologicalProcess modulation by symbiont of host response to gravitational stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response to gravitational stimulus http://purl.obolibrary.org/obo/GO_0033642 GO:0018005 biolink:BiologicalProcess N-terminal peptidyl-glycine N-formylation The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine. RESID:AA0057 go-plus.json http://purl.obolibrary.org/obo/GO_0018005 GO:0018004 biolink:BiologicalProcess N-terminal protein formylation The formylation of the N-terminal amino acid of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0018004 GO:0033641 biolink:BiologicalProcess modulation by symbiont of host response to pH Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033641 GO:0033640 biolink:BiologicalProcess modulation by symbiont of host response to osmotic stress Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033640 CHEBI:58259 biolink:ChemicalSubstance dihydrostreptomycin 3'alpha,6-bisphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58259 chebi_ph7_3 GO:0018001 biolink:BiologicalProcess N-terminal peptidyl-valine acetylation The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine. RESID:AA0054 go-plus.json http://purl.obolibrary.org/obo/GO_0018001 CHEBI:58257 biolink:ChemicalSubstance S-(4-bromophenyl)-L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58257 chebi_ph7_3 GO:0018000 biolink:BiologicalProcess N-terminal peptidyl-tyrosine acetylation The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine. RESID:AA0053 go-plus.json http://purl.obolibrary.org/obo/GO_0018000 CHEBI:58256 biolink:ChemicalSubstance alpha-cyclopiazonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58256 chebi_ph7_3 GO:0033639 biolink:BiologicalProcess modulation by symbiont of host response to water Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033639 GO:0033638 biolink:BiologicalProcess modulation by symbiont of host response to heat Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response to heat shock http://purl.obolibrary.org/obo/GO_0033638 GO:0033637 biolink:BiologicalProcess modulation by symbiont of host response to cold Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json freezing tolerance http://purl.obolibrary.org/obo/GO_0033637 GO:0033636 biolink:BiologicalProcess modulation by symbiont of host response to temperature stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host response to thermal stimulus http://purl.obolibrary.org/obo/GO_0033636 GO:0033635 biolink:BiologicalProcess modulation by symbiont of host response to abiotic stimulus Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033635 GO:0033634 biolink:BiologicalProcess positive regulation of cell-cell adhesion mediated by integrin Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin. go-plus.json positive regulation of cell-cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033634 GO:0008699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008699 CHEBI:83229 biolink:ChemicalSubstance amino acid opine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83229 GO:0008698 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008698 GO:0008697 biolink:MolecularActivity 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. EC:5.3.1.17|RHEA:23896|MetaCyc:5.3.1.17-RXN|KEGG_REACTION:R04383 go-plus.json 4-deoxy-L-threo-5-hexulose uronate isomerase activity|5-keto-4-deoxyuronate isomerase activity|4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity http://purl.obolibrary.org/obo/GO_0008697 CHEBI:83228 biolink:ChemicalSubstance L-alpha-amino acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83228 chebi_ph7_3 GO:0008696 biolink:MolecularActivity 4-amino-4-deoxychorismate lyase activity Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. EC:4.1.3.38|KEGG_REACTION:R05553|RHEA:16201|MetaCyc:ADCLY-RXN go-plus.json para-aminobenzoic acid (PABA) synthase|enzyme X activity|p-aminobenzoate synthetase|4-amino-4-deoxychorismate pyruvate-lyase activity|ADC lyase activity|aminodeoxychorismate lyase activity|4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)|para-aminobenzoic acid synthase http://purl.obolibrary.org/obo/GO_0008696 GO:0008695 biolink:MolecularActivity 3-phenylpropionate dioxygenase activity Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol. RHEA:20357|EC:1.14.12.19|UM-BBD_enzymeID:e0307|MetaCyc:HCAMULTI-RXN go-plus.json HcaA1A2CD|3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity|3-phenylpropanoate dioxygenase activity|Hca dioxygenase activity http://purl.obolibrary.org/obo/GO_0008695 CHEBI:83226 biolink:ChemicalSubstance N(omega)-phospho-L-arginine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_83226 chebi_ph7_3 GO:0008694 biolink:MolecularActivity 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2. EC:4.1.1.98|RHEA:27778|MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN go-plus.json 3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity|3-octaprenyl-4-hydroxybenzoate decarboxylase activity|PPHB decarboxylase activity|UbiD|3-polyprenyl 4-hydroxybenzoate decarboxylase activity|polyprenyl p-hydroxybenzoate decarboxylase activity|UbiX http://purl.obolibrary.org/obo/GO_0008694 GO:0008693 biolink:MolecularActivity 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O. EC:4.2.1.59|RHEA:41860 go-plus.json beta-hydroxyacyl-acyl carrier protein dehydratase activity|FabA|D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity|3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity|beta-hydroxyacyl-ACP dehydrase activity|beta-hydroxydecanoyl thiol ester dehydrase activity|D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|3-hydroxydecanoyl-ACP dehydratase activity|3-hydroxydecanoyl-acyl carrier protein dehydrase activity|HDDase activity|(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity|beta-hydroxydecanoate dehydrase activity|3-hydroxydecanoyl-acyl carrier protein dehydratase activity|beta-hydroxydecanoyl thioester dehydrase activity http://purl.obolibrary.org/obo/GO_0008693 CHEBI:83224 biolink:ChemicalSubstance beta-D-glucosyl-L-erythro-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83224 chebi_ph7_3 CHEBI:83223 biolink:ChemicalSubstance L-erythro-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83223 chebi_ph7_3 GO:0008692 biolink:MolecularActivity 3-hydroxybutyryl-CoA epimerase activity Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA. MetaCyc:OHBUTYRYL-COA-EPIM-RXN|RHEA:21760|EC:5.1.2.3 go-plus.json 3-hydroxyacyl-CoA epimerase activity|3-hydroxybutyryl coenzyme A epimerase activity|3-hydroxybutanoyl-CoA 3-epimerase activity http://purl.obolibrary.org/obo/GO_0008692 CHEBI:58244 biolink:ChemicalSubstance nocardicin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58244 CHEBI:58243 biolink:ChemicalSubstance 5'-adenylyl sulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58243 chebi_ph7_3 CHEBI:58242 biolink:ChemicalSubstance Renilla luciferyl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58242 chebi_ph7_3 CHEBI:58241 biolink:ChemicalSubstance N(2)-(3-carboxylatopropionyl)-L-arginine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58241 chebi_ph7_3 GO:0018018 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018018 CHEBI:58240 biolink:ChemicalSubstance aspulvinone E(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58240 chebi_ph7_3 GO:0018017 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018017 GO:0018019 biolink:BiologicalProcess N-terminal peptidyl-glutamine methylation The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative. RESID:AA0071 go-plus.json http://purl.obolibrary.org/obo/GO_0018019 GO:0018014 biolink:BiologicalProcess N-terminal peptidyl-methionine methylation The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine. RESID:AA0064 go-plus.json http://purl.obolibrary.org/obo/GO_0018014 GO:0033633 biolink:BiologicalProcess negative regulation of cell-cell adhesion mediated by integrin Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin. go-plus.json negative regulation of cell-cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033633 GO:0033632 biolink:BiologicalProcess regulation of cell-cell adhesion mediated by integrin Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin. go-plus.json regulation of cell-cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033632 GO:0018013 biolink:BiologicalProcess N-terminal peptidyl-glycine methylation The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine. RESID:AA0063 go-plus.json http://purl.obolibrary.org/obo/GO_0018013 GO:0018016 biolink:BiologicalProcess N-terminal peptidyl-proline dimethylation The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline. RESID:AA0066 go-plus.json http://purl.obolibrary.org/obo/GO_0018016 GO:0033631 biolink:BiologicalProcess cell-cell adhesion mediated by integrin The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. go-plus.json cell-cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033631 GO:0033630 biolink:BiologicalProcess positive regulation of cell adhesion mediated by integrin Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin. go-plus.json positive regulation of cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033630 GO:0018015 biolink:BiologicalProcess N-terminal peptidyl-phenylalanine methylation The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine. RESID:AA0065 go-plus.json http://purl.obolibrary.org/obo/GO_0018015 CHEBI:58249 biolink:ChemicalSubstance (S,S,S)-nicotianamine trizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58249 chebi_ph7_3 GO:0018010 biolink:MolecularActivity glycoprotein N-palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein. MetaCyc:GLYCOPROTEIN-N-PALMITOYLTRANSFERASE-RXN go-plus.json mucus glycoprotein fatty acyltransferase|palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity http://purl.obolibrary.org/obo/GO_0018010 CHEBI:58248 biolink:ChemicalSubstance 2,3-bisphosphonato-D-glycerate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58248 chebi_ph7_3 CHEBI:58247 biolink:ChemicalSubstance beta-D-glucose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58247 chebi_ph7_3 GO:0018012 biolink:BiologicalProcess N-terminal peptidyl-alanine trimethylation The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine. RESID:AA0062 go-plus.json http://purl.obolibrary.org/obo/GO_0018012 CHEBI:58246 biolink:ChemicalSubstance sulfonatoacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_58246 chebi_ph7_3 CHEBI:58245 biolink:ChemicalSubstance 2'-deoxyadenosine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58245 chebi_ph7_3 GO:0018011 biolink:BiologicalProcess N-terminal peptidyl-alanine methylation The methylation of the N-terminal alanine of proteins. RESID:AA0062|RESID:AA0061 go-plus.json http://purl.obolibrary.org/obo/GO_0018011 GO:0033629 biolink:BiologicalProcess negative regulation of cell adhesion mediated by integrin Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin. go-plus.json negative regulation of cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033629 GO:0033628 biolink:BiologicalProcess regulation of cell adhesion mediated by integrin Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin. go-plus.json regulation of cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033628 GO:0033627 biolink:BiologicalProcess cell adhesion mediated by integrin The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. go-plus.json cell adhesion mediated by integrin complex http://purl.obolibrary.org/obo/GO_0033627 GO:0033626 biolink:BiologicalProcess positive regulation of integrin activation by cell surface receptor linked signal transduction Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands. go-plus.json cell surface receptor linked signal transduction leading to integrin complex activation|cell surface receptor linked signal transduction leading to integrin activation http://purl.obolibrary.org/obo/GO_0033626 GO:0033625 biolink:BiologicalProcess positive regulation of integrin activation Any process that activates or increases the frequency, rate, or extent of integrin activation. go-plus.json positive regulation of integrin complex activation http://purl.obolibrary.org/obo/GO_0033625 GO:0008669 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008669 GO:0008668 biolink:MolecularActivity (2,3-dihydroxybenzoyl)adenylate synthase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate. EC:2.7.7.58|RHEA:20229|KEGG_REACTION:R01504|MetaCyc:DHBAMPLIG-RXN go-plus.json 2,3-dihydroxybenzoate-AMP ligase activity|ATP:2,3-dihydroxybenzoate adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0008668 GO:0033624 biolink:BiologicalProcess negative regulation of integrin activation Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation. go-plus.json negative regulation of integrin complex activation http://purl.obolibrary.org/obo/GO_0033624 GO:0008667 biolink:MolecularActivity 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH. MetaCyc:DHBDEHYD-RXN|EC:1.3.1.28|KEGG_REACTION:R01505|RHEA:23824 go-plus.json 2,3-DHB dehydrogenase activity|2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008667 GO:0033623 biolink:BiologicalProcess regulation of integrin activation Any process that modulates the frequency, rate, or extent of integrin activation. go-plus.json regulation of integrin complex activation http://purl.obolibrary.org/obo/GO_0033623 GO:0008666 biolink:MolecularActivity 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA. KEGG_REACTION:R04365|RHEA:17325|EC:2.3.1.117|MetaCyc:TETHYDPICSUCC-RXN go-plus.json succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity|THDP N-succinyltransferase activity|tetrahydrodipicolinate succinyltransferase activity|tetrahydrodipicolinate N-succinyltransferase activity|succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|tetrahydropicolinate succinylase activity|tetrahydrodipicolinate succinylase activity http://purl.obolibrary.org/obo/GO_0008666 GO:0008665 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008665 RO:0003001 biolink:OntologyClass produced by a produced_by b iff some process that occurs_in b has_output a. RO:0003001 go-plus.json http://purl.obolibrary.org/obo/RO_0003001 GO:0008664 biolink:MolecularActivity 2'-5'-RNA ligase activity Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. go-plus.json 2'-5' RNA ligase activity http://purl.obolibrary.org/obo/GO_0008664 CHEBI:83239 biolink:ChemicalSubstance 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol-5'-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83239 GO:0008663 biolink:MolecularActivity 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate. RHEA:19621|EC:3.1.4.16|MetaCyc:CYCPHOSDIESTER-RXN go-plus.json 2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity|ribonucleoside 2',3'-cyclic phosphate diesterase activity|2',3'-cyclic nucleotidase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2',3 '-cyclic AMP phosphodiesterase activity|2':3'-cyclic phosphodiesterase activity|2',3'-cyclic nucleotide phosphohydrolase|cyclic 2',3'-nucleotide 2'-phosphodiesterase activity|2',3'-cyclic AMP 2'-phosphohydrolase activity|cyclic phosphodiesterase:3'-nucleotidase activity|nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity|cyclic 2',3'-nucleotide phosphodiesterase http://purl.obolibrary.org/obo/GO_0008663 PR:000020320 biolink:Protein insulin receptor proteolytic cleavage product An insulin receptor that has been processed by proteolytic cleavage. go-plus.json INSR/ClvPrd http://purl.obolibrary.org/obo/PR_000020320 GO:0008662 biolink:MolecularActivity 1-phosphofructokinase activity Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate. RHEA:14213|MetaCyc:1PFRUCTPHOSN-RXN|EC:2.7.1.56 go-plus.json ATP:D-fructose-phosphate 6-phosphotransferase activity|fructose-1-phosphate kinase activity|phosphofructokinase 1|1-phosphofructokinase (phosphorylating)|fructose 1-phosphate kinase activity|D-fructose-1-phosphate kinase activity http://purl.obolibrary.org/obo/GO_0008662 CHEBI:83237 biolink:ChemicalSubstance acylglycerophosphoacylglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83237 chebi_ph7_3 GO:0008661 biolink:MolecularActivity 1-deoxy-D-xylulose-5-phosphate synthase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2). MetaCyc:DXS-RXN|EC:2.2.1.7|RHEA:12605|KEGG_REACTION:R05636 go-plus.json DXP-synthase activity|1-deoxyxylulose-5-phosphate synthase activity|1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity|DOXP synthase activity|pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating) http://purl.obolibrary.org/obo/GO_0008661 CHEBI:83236 biolink:ChemicalSubstance 2-acylglycerophospho-(2'-acylglycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83236 chebi_ph7_3 GO:0008660 biolink:MolecularActivity 1-aminocyclopropane-1-carboxylate deaminase activity Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+). EC:3.5.99.7|KEGG_REACTION:R00997|UM-BBD_reactionID:r0357|RHEA:16933|MetaCyc:4.1.99.4-RXN go-plus.json 1-aminocyclopropane carboxylic acid deaminase activity|ACC deaminase activity|1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)|1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity http://purl.obolibrary.org/obo/GO_0008660 RO:0003000 biolink:OntologyClass produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. RO:0003000 go-plus.json http://purl.obolibrary.org/obo/RO_0003000 CHEBI:83235 biolink:ChemicalSubstance beta-D-galactosyl-(1<->1')-sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83235 CHEBI:83234 biolink:ChemicalSubstance beta-D-galactosyl-(1<->1')-sphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83234 chebi_ph7_3 CHEBI:58233 biolink:ChemicalSubstance UDP-L-iduronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58233 chebi_ph7_3 CHEBI:83233 biolink:ChemicalSubstance Mo(=O)(=S)-molybdopterin cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_83233 CHEBI:58232 biolink:ChemicalSubstance D-glucose 1,6-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58232 chebi_ph7_3 CHEBI:58231 biolink:ChemicalSubstance CTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58231 CHEBI:58230 biolink:ChemicalSubstance 2-(beta-D-glucopyranosyluronate)-D-glucuronate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58230 chebi_ph7_3 GO:0033622 biolink:BiologicalProcess integrin activation The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands. go-plus.json integrin complex assembly|integrin complex activation http://purl.obolibrary.org/obo/GO_0033622 GO:0033621 biolink:BiologicalProcess nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. go-plus.json mRNA degradation, meiosis-specific transcripts|degradation of meiosis-specific transcripts|mRNA breakdown, meiosis-specific transcripts|mRNA catabolism, meiosis-specific transcripts|nuclear mRNA catabolic process, meiosis-specific transcripts http://purl.obolibrary.org/obo/GO_0033621 CHEBI:58239 biolink:ChemicalSubstance 16-hydroxytabersoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58239 chebi_ph7_3 GO:0033620 biolink:CellularComponent Mei2 nuclear dot complex A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I. go-plus.json Mei2 dot|Mei2 nuclear dot|nuclear body http://purl.obolibrary.org/obo/GO_0033620 CHEBI:58238 biolink:ChemicalSubstance 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58238 chebi_ph7_3 CHEBI:58237 biolink:ChemicalSubstance cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58237 chebi_ph7_3 CHEBI:58236 biolink:ChemicalSubstance N-feruloylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58236 chebi_ph7_3 CHEBI:2394 biolink:ChemicalSubstance acetochlor go-plus.json http://purl.obolibrary.org/obo/CHEBI_2394 chebi_ph7_3 CHEBI:58234 biolink:ChemicalSubstance 3-hydroxyquininium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58234 chebi_ph7_3 GO:0033619 biolink:BiologicalProcess membrane protein proteolysis The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains. go-plus.json http://purl.obolibrary.org/obo/GO_0033619 GO:0033618 biolink:BiologicalProcess plasma membrane respiratory chain complex IV assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane. go-plus.json plasma membrane cytochrome c oxidase complex assembly|plasma membrane cytochrome c oxidase biogenesis http://purl.obolibrary.org/obo/GO_0033618 GO:0033617 biolink:BiologicalProcess mitochondrial cytochrome c oxidase assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane. go-plus.json mitochondrial cytochrome c oxidase complex assembly|mitochondrial cytochrome c oxidase biogenesis|mitochondrial respiratory chain complex IV assembly http://purl.obolibrary.org/obo/GO_0033617 GO:0033616 biolink:BiologicalProcess plasma membrane proton-transporting ATP synthase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0033616 GO:0033615 biolink:BiologicalProcess mitochondrial proton-transporting ATP synthase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0033615 PR:000020311 biolink:Protein insulin proteolytic cleavage product An insulin that has been processed by proteolytic cleavage. go-plus.json INS/ClvPrd http://purl.obolibrary.org/obo/PR_000020311 GO:0033614 biolink:BiologicalProcess chloroplast proton-transporting ATP synthase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0033614 GO:0033613 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033613 GO:0008679 biolink:MolecularActivity 2-hydroxy-3-oxopropionate reductase activity Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+. EC:1.1.1.60|MetaCyc:TSA-REDUCT-RXN|RHEA:18841 go-plus.json tartronate semialdehyde reductase (NADPH) activity|(R)-glycerate:NAD(P)+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0008679 GO:0008678 biolink:MolecularActivity 2-deoxy-D-gluconate 3-dehydrogenase activity Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+. MetaCyc:KDUD-RXN|RHEA:12160|EC:1.1.1.125 go-plus.json 2-keto-3-deoxygluconate oxidoreductase activity|2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity|2-deoxygluconate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0008678 GO:0033612 biolink:MolecularActivity receptor serine/threonine kinase binding Binding to a receptor that possesses protein serine/threonine kinase activity. go-plus.json transmembrane receptor protein serine/threonine kinase ligand binding http://purl.obolibrary.org/obo/GO_0033612 GO:0008677 biolink:MolecularActivity 2-dehydropantoate 2-reductase activity Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH. KEGG_REACTION:R02472|RHEA:16233|EC:1.1.1.169|MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN go-plus.json 2-oxopantoate reductase activity|2-ketopantoate reductase activity|ketopantoate reductase activity|(R)-pantoate:NADP+ 2-oxidoreductase activity|2-ketopantoic acid reductase activity|KPA reductase activity|ketopantoic acid reductase activity http://purl.obolibrary.org/obo/GO_0008677 GO:0043003 biolink:BiologicalProcess positive regulation of Golgi to plasma membrane CFTR protein transport Any process that activates or increases the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. go-plus.json upregulation of Golgi to plasma membrane CFTR protein transport|up regulation of Golgi to plasma membrane CFTR protein transport|activation of Golgi to plasma membrane CFTR protein transport|stimulation of Golgi to plasma membrane CFTR protein transport|up-regulation of Golgi to plasma membrane CFTR protein transport http://purl.obolibrary.org/obo/GO_0043003 GO:0008676 biolink:MolecularActivity 3-deoxy-8-phosphooctulonate synthase activity Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate. MetaCyc:KDO-8PSYNTH-RXN|EC:2.5.1.55|KEGG_REACTION:R03254|RHEA:14053 go-plus.json KDO-8-phosphate synthetase activity|phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity|KDOP synthase activity|2-keto-3-deoxy-8-phosphooctonic synthetase activity|2-dehydro-3-deoxy-phosphooctonate aldolase activity|3-deoxyoctulosonic 8-phosphate synthetase activity|phospho-2-keto-3-deoxyoctonate aldolase activity|3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity|2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity|2-dehydro-3-deoxyphosphooctonate aldolase activity|3-deoxy-D-manno-octulosonate-8-phosphate synthase activity|KDO-8-P synthase activity http://purl.obolibrary.org/obo/GO_0008676 GO:0043002 biolink:BiologicalProcess negative regulation of Golgi to plasma membrane CFTR protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. go-plus.json down regulation of Golgi to plasma membrane CFTR protein transport|downregulation of Golgi to plasma membrane CFTR protein transport|down-regulation of Golgi to plasma membrane CFTR protein transport|inhibition of Golgi to plasma membrane CFTR protein transport http://purl.obolibrary.org/obo/GO_0043002 GO:0008675 biolink:MolecularActivity 2-dehydro-3-deoxy-phosphogluconate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate. EC:4.1.2.14|MetaCyc:KDPGALDOL-RXN|RHEA:17089 go-plus.json ODPG aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|2-keto-3-deoxygluconate-6-P-aldolase activity|KDPG-aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|2-keto-3-deoxygluconate-6-phosphate aldolase activity|6-phospho-2-keto-3-deoxygluconate aldolase activity|2-keto-3-deoxy-6-phosphogluconic aldolase activity|2-oxo-3-deoxy-6-phosphogluconate aldolase activity|phospho-2-keto-3-deoxygluconic aldolase activity|phospho-2-keto-3-deoxygluconate aldolase activity|phospho-2-dehydro-3-deoxygluconate aldolase activity|2-keto-3-deoxy-6-phosphogluconate aldolase activity|KDPG aldolase activity http://purl.obolibrary.org/obo/GO_0008675 GO:0043005 biolink:CellularComponent neuron projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. NIF_Subcellular:sao867568886 go-plus.json neuron protrusion|neurite|neuronal cell projection|nerve fiber|neuron process http://purl.obolibrary.org/obo/GO_0043005 goslim_pir GO:0008674 biolink:MolecularActivity 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate. EC:4.1.2.21|MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN|RHEA:24464|KEGG_REACTION:R01064 go-plus.json 2-keto-3-deoxy-6-phosphogalactonic aldolase activity|2-oxo-3-deoxygalactonate 6-phosphate aldolase activity|phospho-2-keto-3-deoxygalactonic aldolase activity|6-phospho-2-dehydro-3-deoxygalactonate aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|(KDPGal)aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|2-dehydro-3-deoxyphosphogalactonate aldolase activity|2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity|6-phospho-2-keto-3-deoxygalactonate aldolase activity|phospho-2-keto-3-deoxygalactonate aldolase activity http://purl.obolibrary.org/obo/GO_0008674 GO:0043004 biolink:BiologicalProcess cytoplasmic sequestering of CFTR protein The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane. go-plus.json cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein|storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein)|maintenance of CFTR protein location in cytoplasm|sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein|cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein http://purl.obolibrary.org/obo/GO_0043004 CHEBI:83249 biolink:ChemicalSubstance N-(2-hydroxyacyl)-beta-D-galactosylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83249 chebi_ph7_3 CHEBI:83248 biolink:ChemicalSubstance N-(2-hydroxyhexanoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83248 chebi_ph7_3 GO:0008673 biolink:MolecularActivity 2-dehydro-3-deoxygluconokinase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+). EC:2.7.1.45|MetaCyc:DEOXYGLUCONOKIN-RXN|KEGG_REACTION:R01541|RHEA:14797 go-plus.json 2-keto-3-deoxygluconokinase (phosphorylating)|ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity|2-keto-3-deoxygluconate kinase activity|3-deoxy-2-oxo-D-gluconate kinase activity|ketodeoxygluconokinase activity|2-keto-3-deoxygluconokinase activity|2-keto-3-deoxy-D-gluconic acid kinase activity|KDG kinase activity http://purl.obolibrary.org/obo/GO_0008673 CHEBI:83247 biolink:ChemicalSubstance N-(2-hydroxyacyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83247 chebi_ph7_3 GO:0008672 biolink:MolecularActivity 2-dehydro-3-deoxyglucarate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde. MetaCyc:KDGALDOL-RXN|EC:4.1.2.20|RHEA:10268 go-plus.json 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)|2-keto-3-deoxyglucarate aldolase activity|alpha-keto-beta-deoxy-D-glucarate aldolase activity|2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity http://purl.obolibrary.org/obo/GO_0008672 CHEBI:83246 biolink:ChemicalSubstance N-(2-hydroxyhexanoyl)-beta-D-galactosylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83246 chebi_ph7_3 GO:0008671 biolink:MolecularActivity 2-dehydro-3-deoxygalactonokinase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+). EC:2.7.1.58|RHEA:16525|KEGG_REACTION:R03387|MetaCyc:DEHYDDEOXGALACTKIN-RXN go-plus.json 2-keto-3-deoxygalactonokinase activity|2-keto-3-deoxygalactonate kinase (phosphorylating)|2-keto-3-deoxy-galactonokinase activity|2-oxo-3-deoxygalactonate kinase activity|ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0008671 GO:0043001 biolink:BiologicalProcess Golgi to plasma membrane protein transport The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0043001 CHEBI:83245 biolink:ChemicalSubstance N-(2-hydroxyacyl)-beta-D-galactosylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83245 chebi_ph7_3 GO:0008670 biolink:MolecularActivity 2,4-dienoyl-CoA reductase (NADPH) activity Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+. EC:1.3.1.34|RHEA:12136|MetaCyc:DIENOYLCOAREDUCT-RXN go-plus.json 4-enoyl-CoA reductase (NADPH2)|4-enoyl-CoA reductase activity|4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity|4-enoyl-CoA reductase (NADPH) activity http://purl.obolibrary.org/obo/GO_0008670 GO:0043000 biolink:BiologicalProcess Golgi to plasma membrane CFTR protein transport The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. go-plus.json Golgi to plasma membrane cystic fibrosis transmembrane conductance regulator protein transport http://purl.obolibrary.org/obo/GO_0043000 GO:0008680 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008680 CHEBI:83244 biolink:ChemicalSubstance N-(2-hydroxyhexanoyl)sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83244 chebi_ph7_3 CHEBI:58222 biolink:ChemicalSubstance 4-hydroxy-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58222 chebi_ph7_3 CHEBI:83243 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate)(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83243 chebi_ph7_3 CHEBI:83242 biolink:ChemicalSubstance 1D-myo-inositol 1,3-biphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83242 chebi_ph7_3 CHEBI:58220 biolink:ChemicalSubstance N-adenylyl-L-phenylalanate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58220 chebi_ph7_3 CHEBI:83241 biolink:ChemicalSubstance 1D-myo-inositol 3,4-biphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83241 chebi_ph7_3 GO:0043007 biolink:BiologicalProcess maintenance of rDNA Any process involved in sustaining the fidelity and copy number of rDNA repeats. go-plus.json rDNA maintenance|ribosomal DNA maintenance http://purl.obolibrary.org/obo/GO_0043007 CHEBI:83240 biolink:ChemicalSubstance 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83240 GO:0043006 biolink:BiologicalProcess activation of phospholipase A2 activity by calcium-mediated signaling A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal. go-plus.json calcium-dependent phospholipase A2 activation|activation of phospholipase A2 activity by calcium-mediated signalling|calcium-dependent activation of phospholipase A2 http://purl.obolibrary.org/obo/GO_0043006 GO:0043009 biolink:BiologicalProcess chordate embryonic development The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. go-plus.json http://purl.obolibrary.org/obo/GO_0043009 GO:0043008 biolink:MolecularActivity ATP-dependent protein binding Binding to a protein or protein complex using energy from ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0043008 goslim_chembl GO:0033611 biolink:BiologicalProcess oxalate catabolic process The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate. go-plus.json ethanedioate catabolic process|oxalate degradation|oxalate breakdown|ethanedioic acid catabolic process|oxalate catabolism|oxalic acid catabolic process http://purl.obolibrary.org/obo/GO_0033611 GO:0033610 biolink:BiologicalProcess oxalate biosynthetic process The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate. go-plus.json ethanedioate biosynthetic process|oxalic acid biosynthetic process|oxalate anabolism|ethanedioic acid biosynthetic process|oxalate synthesis|oxalate formation|oxalate biosynthesis http://purl.obolibrary.org/obo/GO_0033610 CHEBI:58229 biolink:ChemicalSubstance Watasenia luciferin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58229 chebi_ph7_3 CHEBI:58228 biolink:ChemicalSubstance carbamoyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58228 chebi_ph7_3 CHEBI:58227 biolink:ChemicalSubstance 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58227 chebi_ph7_3 CHEBI:58226 biolink:ChemicalSubstance L-ribulose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58226 chebi_ph7_3 CHEBI:58225 biolink:ChemicalSubstance alpha-D-glucose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58225 chebi_ph7_3 CHEBI:58224 biolink:ChemicalSubstance GDP-6-deoxy-alpha-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58224 chebi_ph7_3 CHEBI:58223 biolink:ChemicalSubstance UDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58223 chebi_ph7_3 GO:0033608 biolink:MolecularActivity formyl-CoA transferase activity Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA. MetaCyc:RXN0-1382|EC:2.8.3.16|RHEA:16545|KEGG_REACTION:R07290 go-plus.json formyl-CoA:oxalate CoA-transferase activity|formyl-coenzyme A transferase activity|formyl-CoA oxalate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0033608 GO:0033607 biolink:CellularComponent SOD1-Bcl-2 complex A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0033607 GO:0033606 biolink:BiologicalProcess chemokine receptor transport within lipid bilayer The directed movement of a chemokine receptor within a lipid bilayer. go-plus.json chemokine receptor translocation within membrane http://purl.obolibrary.org/obo/GO_0033606 GO:0008649 biolink:MolecularActivity rRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0008649 GO:0033605 biolink:BiologicalProcess positive regulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. go-plus.json up-regulation of catecholamine secretion|upregulation of catecholamine secretion|up regulation of catecholamine secretion|activation of catecholamine secretion|stimulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0033605 GO:0033604 biolink:BiologicalProcess negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. go-plus.json inhibition of catecholamine secretion|down regulation of catecholamine secretion|downregulation of catecholamine secretion|down-regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0033604 GO:0008648 biolink:MolecularActivity obsolete tachykinin OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation. go-plus.json tachykinin http://purl.obolibrary.org/obo/GO_0008648 GO:0033603 biolink:BiologicalProcess positive regulation of dopamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. go-plus.json upregulation of dopamine secretion|stimulation of dopamine secretion|up-regulation of dopamine secretion|activation of dopamine secretion|up regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033603 GO:0008647 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008647 GO:0033602 biolink:BiologicalProcess negative regulation of dopamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. go-plus.json down regulation of dopamine secretion|inhibition of dopamine secretion|down-regulation of dopamine secretion|downregulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033602 GO:0008646 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008646 GO:0008645 biolink:BiologicalProcess hexose transmembrane transport The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule. go-plus.json hexose transport|high-affinity hexose transport|low-affinity hexose transport|hexose membrane transport http://purl.obolibrary.org/obo/GO_0008645 GO:0033601 biolink:BiologicalProcess positive regulation of mammary gland epithelial cell proliferation Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation. go-plus.json up-regulation of mammary gland epithelial cell proliferation|upregulation of mammary gland epithelial cell proliferation|up regulation of mammary gland epithelial cell proliferation|activation of mammary gland epithelial cell proliferation|stimulation of mammary gland epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0033601 GO:0043014 biolink:MolecularActivity alpha-tubulin binding Binding to the microtubule constituent protein alpha-tubulin. go-plus.json alpha tubulin binding http://purl.obolibrary.org/obo/GO_0043014 GO:0008644 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008644 GO:0008643 biolink:BiologicalProcess carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. go-plus.json sugar transport http://purl.obolibrary.org/obo/GO_0008643 goslim_yeast|goslim_pir GO:0043013 biolink:BiologicalProcess negative regulation of fusion of sperm to egg plasma membrane Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane. go-plus.json down regulation of fusion of sperm to egg plasma membrane|inhibition of fusion of sperm to egg plasma membrane|negative regulation of sperm-oocyte fusion|down-regulation of fusion of sperm to egg plasma membrane|downregulation of fusion of sperm to egg plasma membrane|inhibition of sperm-oocyte fusion http://purl.obolibrary.org/obo/GO_0043013 GO:0008642 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008642 GO:0043016 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043016 GO:0008641 biolink:MolecularActivity ubiquitin-like modifier activating enzyme activity Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json small protein activating enzyme activity http://purl.obolibrary.org/obo/GO_0008641 goslim_pir GO:0043015 biolink:MolecularActivity gamma-tubulin binding Binding to the microtubule constituent protein gamma-tubulin. go-plus.json gamma tubulin binding http://purl.obolibrary.org/obo/GO_0043015 GO:0043010 biolink:BiologicalProcess camera-type eye development The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. go-plus.json http://purl.obolibrary.org/obo/GO_0043010 GO:0008640 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008640 CHEBI:48891 biolink:ChemicalSubstance thiazolidinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_48891 CHEBI:83257 biolink:ChemicalSubstance N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83257 chebi_ph7_3 GO:0043012 biolink:BiologicalProcess regulation of fusion of sperm to egg plasma membrane Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane. go-plus.json regulation of sperm-oocyte fusion http://purl.obolibrary.org/obo/GO_0043012 GO:0033609 biolink:BiologicalProcess oxalate metabolic process The chemical reactions and pathways involving oxalate, the organic acid ethanedioate. go-plus.json ethanedioic acid metabolic process|oxalic acid metabolic process|oxalate metabolism|ethanedioate metabolic process http://purl.obolibrary.org/obo/GO_0033609 GO:0043011 biolink:BiologicalProcess myeloid dendritic cell differentiation The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. Wikipedia:Dendritic_cell go-plus.json http://purl.obolibrary.org/obo/GO_0043011 CHEBI:58211 biolink:ChemicalSubstance dolichyl beta-D-mannosyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58211 chebi_ph7_3 CHEBI:58210 biolink:ChemicalSubstance FMN(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58210 chebi_ph7_3 CHEBI:10275 biolink:ChemicalSubstance (9Z,11E,13E)-octadeca-9,11,13-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_10275 GO:0043018 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043018 GO:0043017 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043017 GO:0043019 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043019 CHEBI:10278 biolink:ChemicalSubstance alpha-eudesmol go-plus.json http://purl.obolibrary.org/obo/CHEBI_10278 chebi_ph7_3 GO:0033600 biolink:BiologicalProcess negative regulation of mammary gland epithelial cell proliferation Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation. go-plus.json inhibition of mammary gland epithelial cell proliferation|down regulation of mammary gland epithelial cell proliferation|downregulation of mammary gland epithelial cell proliferation|down-regulation of mammary gland epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0033600 CHEBI:58219 biolink:ChemicalSubstance mevaldate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58219 chebi_ph7_3 CHEBI:58218 biolink:ChemicalSubstance 9-riburonosylhypoxanthine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58218 chebi_ph7_3 OBO:GOCHE_25512 biolink:OntologyClass substance with neurotransmitter role go-plus.json http://purl.obolibrary.org/obo/GOCHE_25512 3_STAR CHEBI:58217 biolink:ChemicalSubstance pentachlorophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58217 chebi_ph7_3 CHEBI:58215 biolink:ChemicalSubstance guanosine 3',5'-bis(diphosphate)(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58215 CHEBI:58214 biolink:ChemicalSubstance kanamycin A(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58214 chebi_ph7_3 CHEBI:58213 biolink:ChemicalSubstance ammonioacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_58213 chebi_ph7_3 CHEBI:58212 biolink:ChemicalSubstance dUTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58212 CHEBI:48887 biolink:ChemicalSubstance bile acid metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_48887 GO:0008659 biolink:MolecularActivity (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O. EC:4.2.1.59|RHEA:41892 go-plus.json (3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity|(3R)-hydroxymyristoyl-ACP dehydratase activity http://purl.obolibrary.org/obo/GO_0008659 GO:0008658 biolink:MolecularActivity penicillin binding Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json http://purl.obolibrary.org/obo/GO_0008658 goslim_metagenomics GO:0008657 biolink:MolecularActivity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. go-plus.json DNA gyrase inhibitor activity http://purl.obolibrary.org/obo/GO_0008657 CHEBI:58209 biolink:ChemicalSubstance 4-(3-methylbut-2-enyl)-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58209 chebi_ph7_3 GO:0008656 biolink:MolecularActivity cysteine-type endopeptidase activator activity involved in apoptotic process Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process. Reactome:R-HSA-205117|Reactome:R-HSA-449073 go-plus.json caspase activator activity http://purl.obolibrary.org/obo/GO_0008656 GO:0043025 biolink:CellularComponent neuronal cell body The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. NIF_Subcellular:sao1044911821|Wikipedia:Soma_(biology) go-plus.json neuron cell body|neuronal cell soma http://purl.obolibrary.org/obo/GO_0043025 goslim_pir GO:0008655 biolink:BiologicalProcess pyrimidine-containing compound salvage Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis. go-plus.json pyrimidine salvage http://purl.obolibrary.org/obo/GO_0008655 goslim_pir GO:0043024 biolink:MolecularActivity ribosomal small subunit binding Binding to a small ribosomal subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0043024 GO:0008654 biolink:BiologicalProcess phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester. MetaCyc:PHOSLIPSYN2-PWY|MetaCyc:LIPASYN-PWY|MetaCyc:PHOSLIPSYN-PWY go-plus.json phospholipid biosynthesis|phospholipid anabolism|phospholipid synthesis|phospholipid formation http://purl.obolibrary.org/obo/GO_0008654 GO:0008653 biolink:BiologicalProcess lipopolysaccharide metabolic process The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. go-plus.json LPS metabolic process|lipopolysaccharide metabolism http://purl.obolibrary.org/obo/GO_0008653 GO:0043027 biolink:MolecularActivity cysteine-type endopeptidase inhibitor activity involved in apoptotic process Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process. go-plus.json caspase inhibitor activity http://purl.obolibrary.org/obo/GO_0043027 GO:0008652 biolink:BiologicalProcess cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. Wikipedia:Amino_acid_synthesis go-plus.json cellular amino acid biosynthesis|cellular amino acid anabolism|amino acid biosynthetic process|cellular amino acid synthesis|cellular amino acid formation http://purl.obolibrary.org/obo/GO_0008652 GO:0043026 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043026 GO:0043021 biolink:MolecularActivity ribonucleoprotein complex binding Binding to a complex of RNA and protein. go-plus.json protein-RNA complex binding|RNP binding|ribonucleoprotein binding http://purl.obolibrary.org/obo/GO_0043021 goslim_pir GO:0008651 biolink:MolecularActivity obsolete actin polymerizing activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json actin polymerizing activity http://purl.obolibrary.org/obo/GO_0008651 GO:0008650 biolink:MolecularActivity rRNA (uridine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine. Reactome:R-HSA-6793127 go-plus.json http://purl.obolibrary.org/obo/GO_0008650 GO:0043020 biolink:CellularComponent NADPH oxidase complex A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. go-plus.json respiratory-burst oxidase|flavocytochrome b558 http://purl.obolibrary.org/obo/GO_0043020 GO:0043023 biolink:MolecularActivity ribosomal large subunit binding Binding to a large ribosomal subunit. go-plus.json http://purl.obolibrary.org/obo/GO_0043023 GO:0043022 biolink:MolecularActivity ribosome binding Binding to a ribosome. go-plus.json ribosome receptor activity http://purl.obolibrary.org/obo/GO_0043022 CHEBI:48882 biolink:ChemicalSubstance (R)-atropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_48882 CHEBI:58200 biolink:ChemicalSubstance N(5)-methyl-L-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58200 chebi_ph7_3 CHEBI:83264 biolink:ChemicalSubstance beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_83264 chebi_ph7_3 GO:0043029 biolink:BiologicalProcess T cell homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. go-plus.json T lymphocyte homeostasis|T-cell homeostasis|T-lymphocyte homeostasis http://purl.obolibrary.org/obo/GO_0043029 CHEBI:83262 biolink:ChemicalSubstance alkyl,acyl-3-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_83262 chebi_ph7_3 GO:0043028 biolink:MolecularActivity cysteine-type endopeptidase regulator activity involved in apoptotic process Binds to and modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process. go-plus.json caspase regulator activity http://purl.obolibrary.org/obo/GO_0043028 CHEBI:58207 biolink:ChemicalSubstance 5-methyltetrahydropteroyltri-L-glutamate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58207 chebi_ph7_3 CHEBI:58206 biolink:ChemicalSubstance all-trans-heptaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58206 chebi_ph7_3 CHEBI:58205 biolink:ChemicalSubstance 3-nitroacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58205 chebi_ph7_3 CHEBI:58203 biolink:ChemicalSubstance 2-formylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58203 chebi_ph7_3 CHEBI:58202 biolink:ChemicalSubstance N(6)-methyl-L-lysinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58202 chebi_ph7_3 CHEBI:58201 biolink:ChemicalSubstance 6,7-dimethyl-8-(1-D-ribityl)lumazine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58201 chebi_ph7_3 GO:0008629 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008629 CHEBI:48873 biolink:ChemicalSubstance cholinergic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48873 GO:0008628 biolink:BiologicalProcess hormone-mediated apoptotic signaling pathway A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered. go-plus.json induction of apoptosis by hormones|apoptotic signaling pathway in response to hormone http://purl.obolibrary.org/obo/GO_0008628 GO:0043030 biolink:BiologicalProcess regulation of macrophage activation Any process that modulates the frequency or rate of macrophage activation. go-plus.json regulation of macrophage polarization http://purl.obolibrary.org/obo/GO_0043030 CHEBI:48876 biolink:ChemicalSubstance muscarinic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48876 GO:0008627 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to osmotic stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered. go-plus.json induction of apoptosis by ionic changes http://purl.obolibrary.org/obo/GO_0008627 GO:0008626 biolink:BiologicalProcess granzyme-mediated apoptotic signaling pathway A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. go-plus.json apoptotic signaling pathway in response to granzyme|induction of apoptosis by granzyme http://purl.obolibrary.org/obo/GO_0008626 CHEBI:48878 biolink:ChemicalSubstance nicotinic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_48878 GO:0008625 biolink:BiologicalProcess extrinsic apoptotic signaling pathway via death domain receptors A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered. go-plus.json induction of apoptosis via death domain receptors|death receptor-mediated apoptosis|induction of apoptosis via death receptors http://purl.obolibrary.org/obo/GO_0008625 GO:0008624 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008624 GO:0008623 biolink:CellularComponent CHRAC An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair. go-plus.json chromatin accessibility complex|ISW2 complex http://purl.obolibrary.org/obo/GO_0008623 GO:0008622 biolink:CellularComponent epsilon DNA polymerase complex A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair. go-plus.json DNA polymerase epsilon complex http://purl.obolibrary.org/obo/GO_0008622 GO:0043036 biolink:CellularComponent starch grain Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. go-plus.json starch granule http://purl.obolibrary.org/obo/GO_0043036 GO:0043035 biolink:MolecularActivity chromatin insulator sequence binding Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0043035 GO:0008621 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008621 GO:0043038 biolink:BiologicalProcess amino acid activation The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0043038 GO:0008620 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008620 GO:0043037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043037 GO:0043032 biolink:BiologicalProcess positive regulation of macrophage activation Any process that stimulates, induces or increases the rate of macrophage activation. go-plus.json up regulation of macrophage activation|activation of macrophage activation|stimulation of macrophage activation|up-regulation of macrophage activation|positive regulation of macrophage polarization|upregulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043032 CHEBI:48870 biolink:ChemicalSubstance idaric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_48870 GO:0043031 biolink:BiologicalProcess negative regulation of macrophage activation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. go-plus.json downregulation of macrophage activation|down-regulation of macrophage activation|inhibition of macrophage activation|negative regulation of macrophage polarization|down regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043031 GO:0043034 biolink:CellularComponent costamere Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix. Wikipedia:Costamere go-plus.json http://purl.obolibrary.org/obo/GO_0043034 GO:0043033 biolink:CellularComponent isoamylase complex A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. go-plus.json debranching enzyme complex http://purl.obolibrary.org/obo/GO_0043033 goslim_pir CHEBI:48871 biolink:ChemicalSubstance galactaric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_48871 CHEBI:83276 biolink:ChemicalSubstance (2E,6E)-farnesoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83276 chebi_ph7_3 CHEBI:83274 biolink:ChemicalSubstance juvenile hormone III carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_83274 chebi_ph7_3 CHEBI:83273 biolink:ChemicalSubstance N-acylsphingoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83273 chebi_ph7_3 GO:0043039 biolink:BiologicalProcess tRNA aminoacylation The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. go-plus.json tRNA charging|aminoacyl-tRNA biosynthetic process|aminoacyl-tRNA biosynthesis http://purl.obolibrary.org/obo/GO_0043039 CHEBI:34227 biolink:ChemicalSubstance 2,3-di-O-phytanyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34227 chebi_ph7_3 CHEBI:48863 biolink:ChemicalSubstance phycocyanobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_48863 GO:0043041 biolink:BiologicalProcess amino acid activation for nonribosomal peptide biosynthetic process Activation of an amino acid for incorporation into a peptide by a nonribosomal process. go-plus.json nonribosomal amino acid activation http://purl.obolibrary.org/obo/GO_0043041 GO:0008639 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008639 GO:0043040 biolink:BiologicalProcess tRNA aminoacylation for nonribosomal peptide biosynthetic process The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis. go-plus.json tRNA aminoacylation for nonribosomal peptide formation|tRNA aminoacylation for nonribosomal peptide biosynthesis|tRNA aminoacylation for nonribosomal peptide anabolism|tRNA aminoacylation for nonribosomal peptide synthesis http://purl.obolibrary.org/obo/GO_0043040 GO:0008638 biolink:MolecularActivity obsolete protein tagging activity OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation. go-plus.json protein tagging activity http://purl.obolibrary.org/obo/GO_0008638 CHEBI:48867 biolink:ChemicalSubstance 4-(trimethylammonio)but-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48867 GO:0008637 biolink:BiologicalProcess apoptotic mitochondrial changes The morphological and physiological alterations undergone by mitochondria during apoptosis. go-plus.json http://purl.obolibrary.org/obo/GO_0008637 GO:0008636 biolink:BiologicalProcess obsolete activation of caspase activity by protein phosphorylation OBSOLETE. Upregulation of the activity of a caspase, a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group. go-plus.json caspase activation via phosphorylation|activation of caspase activity by protein amino acid phosphorylation|activation of caspase activity by protein phosphorylation http://purl.obolibrary.org/obo/GO_0008636 GO:0008635 biolink:BiologicalProcess activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c. go-plus.json activation of caspase activity by cytochrome c|caspase activation via cytochrome c http://purl.obolibrary.org/obo/GO_0008635 CHEBI:48869 biolink:ChemicalSubstance 3-O-(geranylgeranyl)glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48869 GO:0008634 biolink:BiologicalProcess obsolete negative regulation of survival gene product expression OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. go-plus.json negative regulation of survival gene products|down-regulation of survival gene product activity|inhibition of survival gene product activity|downregulation of survival gene product activity|negative regulation of survival gene product expression|down regulation of survival gene product activity|negative regulation of survival gene product activity http://purl.obolibrary.org/obo/GO_0008634 CHEBI:48868 biolink:ChemicalSubstance sn-1-O-(geranylgeranyl)glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48868 PR:000020357 biolink:Protein insulin-like growth factor I proteolytic cleavage product An insulin-like growth factor I that has been processed by proteolytic cleavage. go-plus.json IGF1/ClvPrd http://purl.obolibrary.org/obo/PR_000020357 GO:0043047 biolink:MolecularActivity single-stranded telomeric DNA binding Binding to single-stranded telomere-associated DNA. go-plus.json telomeric ssDNA binding http://purl.obolibrary.org/obo/GO_0043047 GO:0008633 biolink:BiologicalProcess obsolete activation of pro-apoptotic gene products OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form. go-plus.json activation of pro-apoptotic gene products|induction of pro-apoptotic gene products http://purl.obolibrary.org/obo/GO_0008633 GO:0043046 biolink:BiologicalProcess DNA methylation involved in gamete generation The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete. go-plus.json de novo DNA methylation http://purl.obolibrary.org/obo/GO_0043046 GO:0008632 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008632 GO:0008631 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to oxidative stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. go-plus.json induction of apoptosis by oxidative stress|oxidative stress-induced intrinsic apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0008631 GO:0043049 biolink:BiologicalProcess otic placode formation The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain. go-plus.json http://purl.obolibrary.org/obo/GO_0043049 GO:0008630 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to DNA damage A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. go-plus.json DNA damage response, signal transduction resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_0008630 GO:0043048 biolink:BiologicalProcess dolichyl monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative. go-plus.json dolichyl monophosphate anabolism|dolichyl monophosphate biosynthesis|dolichyl monophosphate synthesis|dolichyl monophosphate formation http://purl.obolibrary.org/obo/GO_0043048 GO:0043043 biolink:BiologicalProcess peptide biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. go-plus.json peptide anabolism|peptide synthesis|peptide formation|peptide biosynthesis http://purl.obolibrary.org/obo/GO_0043043 GO:0043042 biolink:BiologicalProcess amino acid adenylylation by nonribosomal peptide synthase Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor. go-plus.json amino acid adenylation by NRPS|amino acid adenylation by nonribosomal peptide synthase http://purl.obolibrary.org/obo/GO_0043042 GO:0043045 biolink:BiologicalProcess DNA methylation involved in embryo development The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression. go-plus.json de novo DNA methylation http://purl.obolibrary.org/obo/GO_0043045 CHEBI:48861 biolink:ChemicalSubstance 2-trans,6-trans,10-trans-geranylgeranyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_48861 GO:0043044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0043044 CHEBI:34238 biolink:ChemicalSubstance 2,4-dibromophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_34238 chebi_ph7_3 CHEBI:10280 biolink:ChemicalSubstance (E,E)-alpha-farnesene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10280 chebi_ph7_3 CHEBI:83280 biolink:ChemicalSubstance flavone C-glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_83280 CHEBI:10283 biolink:ChemicalSubstance 2-hydroxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_10283 GO:0018094 biolink:BiologicalProcess protein polyglycylation The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid. RESID:AA0201 go-plus.json http://purl.obolibrary.org/obo/GO_0018094 GO:0018093 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018093 GO:0018096 biolink:BiologicalProcess peptide cross-linking via S-(2-aminovinyl)-D-cysteine The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine. RESID:AA0204 go-plus.json http://purl.obolibrary.org/obo/GO_0018096 GO:0018095 biolink:BiologicalProcess protein polyglutamylation The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid. RESID:AA0202 go-plus.json http://purl.obolibrary.org/obo/GO_0018095 GO:0018090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018090 GO:0018092 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018092 GO:0018091 biolink:BiologicalProcess peptidyl-asparagine racemization The racemization of peptidyl-asparagine. RESID:AA0196 go-plus.json http://purl.obolibrary.org/obo/GO_0018091 GO:0018087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018087 GO:0018086 biolink:BiologicalProcess obsolete alanine racemization OBSOLETE. (Was not defined before being made obsolete). go-plus.json alanine racemization http://purl.obolibrary.org/obo/GO_0018086 GO:0018089 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018089 GO:0018088 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018088 GO:0018097 biolink:BiologicalProcess protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine. RESID:AA0207 go-plus.json protein amino acid cinnamylation http://purl.obolibrary.org/obo/GO_0018097 GO:0018072 biolink:BiologicalProcess peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit. RESID:AA0170 go-plus.json peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine anabolism from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine synthesis from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine formation from peptidyl-glutamic acid http://purl.obolibrary.org/obo/GO_0018072 GO:0018071 biolink:MolecularActivity NAD(P)-cysteine ADP-ribosyltransferase activity Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0018071 GO:0018074 biolink:BiologicalProcess peptidyl-histidine bromination The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown. RESID:AA0173 go-plus.json http://purl.obolibrary.org/obo/GO_0018074 GO:0018073 biolink:BiologicalProcess protein bromination The addition of one or more bromine atoms to an amino acid residue in a protein. go-plus.json protein amino acid bromination http://purl.obolibrary.org/obo/GO_0018073 GO:0018070 biolink:BiologicalProcess peptidyl-serine phosphopantetheinylation The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine. RESID:AA0150 go-plus.json http://purl.obolibrary.org/obo/GO_0018070 GO:0018069 biolink:BiologicalProcess peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase. RESID:AA0149 go-plus.json http://purl.obolibrary.org/obo/GO_0018069 GO:0018068 biolink:BiologicalProcess peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases. RESID:AA0147 go-plus.json peptidyl-L-2',4',5'-topaquinone formation from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone synthesis from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone anabolism from peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0018068 GO:0018065 biolink:BiologicalProcess obsolete protein-cofactor linkage OBSOLETE. The covalent attachment of a cofactor to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018065 GO:0018064 biolink:MolecularActivity protein-L-histidine N-tele-methyltransferase activity Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine. RHEA:19369|MetaCyc:2.1.1.85-RXN|EC:2.1.1.85 go-plus.json peptidyl-histidine N-methyltransferase activity|protein methylase IV activity|protein-histidine N-methyltransferase activity|S-adenosyl methionine:protein-histidine N-methyltransferase activity|S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity|actin-specific histidine methyltransferase activity|protein (histidine) methyltransferase activity http://purl.obolibrary.org/obo/GO_0018064 GO:0018067 biolink:BiologicalProcess peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA). RESID:AA0146 go-plus.json peptidyl-L-3',4'-dihydroxyphenylalanine formation from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine synthesis from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine anabolism from peptidyl-tyrosine http://purl.obolibrary.org/obo/GO_0018067 CHEBI:73841 biolink:ChemicalSubstance lysophosphatidylcholine (P-16:0/0:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73841 chebi_ph7_3 GO:0018083 biolink:BiologicalProcess peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases. RESID:AA0185 go-plus.json peptidyl-L-3-oxoalanine anabolism from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine synthesis from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine formation from peptidyl-cysteine or peptidyl-serine http://purl.obolibrary.org/obo/GO_0018083 GO:0018082 biolink:BiologicalProcess peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine. RESID:AA0182 go-plus.json peptidyl-(Z)-dehydrobutyrine anabolism from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine synthesis from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine formation from peptidyl-threonine http://purl.obolibrary.org/obo/GO_0018082 GO:0018085 biolink:BiologicalProcess peptidyl-L-amino acid racemization The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid. go-plus.json http://purl.obolibrary.org/obo/GO_0018085 GO:0018084 biolink:BiologicalProcess peptidyl-lactic acid biosynthetic process from peptidyl-serine The modification of N-terminal peptidyl-serine to lactic acid. RESID:AA0186 go-plus.json peptidyl-lactic acid formation from peptidyl-serine|peptidyl-lactic acid synthesis from peptidyl-serine|peptidyl-lactic acid anabolism from peptidyl-serine http://purl.obolibrary.org/obo/GO_0018084 GO:0018081 biolink:BiologicalProcess peptide cross-linking via lanthionine or 3-methyl-lanthionine The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process. RESID:AA0112|RESID:AA0111|RESID:AA0110 go-plus.json peptide cross-linking via the thiolethers lanthionine or 3-methyl-lanthionine|peptide cross-linking via the thioethers lanthionine or 3-methyl-lanthionine http://purl.obolibrary.org/obo/GO_0018081 GO:0018080 biolink:BiologicalProcess peptidyl-tryptophan bromination The bromination of peptidyl-tryptophan, to form peptidyl-L-6'-bromotryptophan. RESID:AA0179 go-plus.json http://purl.obolibrary.org/obo/GO_0018080 GO:0033691 biolink:MolecularActivity sialic acid binding Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria. go-plus.json N-acetylneuraminic acid binding http://purl.obolibrary.org/obo/GO_0033691 GO:0033690 biolink:BiologicalProcess positive regulation of osteoblast proliferation Any process that activates or increases the rate or extent of osteoblast proliferation. go-plus.json upregulation of osteoblast proliferation|stimulation of osteoblast proliferation|up-regulation of osteoblast proliferation|activation of osteoblast proliferation|up regulation of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0033690 GO:0033699 biolink:MolecularActivity DNA 5'-adenosine monophosphate hydrolase activity Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus. go-plus.json DNA 5'-adenylate hydrolase activity|DNA de-adenylation|DNA adenylate hydrolysis activity|AMP-removal activity|DNA deadenylation http://purl.obolibrary.org/obo/GO_0033699 GO:0018079 biolink:BiologicalProcess protein halogenation The addition of a halogen to a protein amino acid. go-plus.json protein amino acid halogenation http://purl.obolibrary.org/obo/GO_0018079 GO:0033698 biolink:CellularComponent Rpd3L complex A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae). go-plus.json Rpd3C(L)|Clr6L complex|Clr6 histone deacetylase complex I/I' http://purl.obolibrary.org/obo/GO_0033698 GO:0033697 biolink:BiologicalProcess obsolete positive regulation of extent of heterochromatin assembly OBSOLETE. Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin. go-plus.json positive regulation of heterochromatin spreading|positive regulation of extent of heterochromatin formation http://purl.obolibrary.org/obo/GO_0033697 GO:0033696 biolink:BiologicalProcess heterochromatin boundary formation A process that forms a boundary that limits the spreading of heterochromatin along a chromosome. go-plus.json negative regulation of extent of heterochromatin assembly|negative regulation of extent of heterochromatin formation|regulation of heterochromatin spreading|regulation of extent of heterochromatin assembly|maintenance of heterochromatin boundaries|negative regulation of heterochromatin spreading|regulation of extent of heterochromatin formation http://purl.obolibrary.org/obo/GO_0033696 GO:0033695 biolink:MolecularActivity oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule. EC:1.17.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0033695 GO:0018076 biolink:BiologicalProcess N-terminal peptidyl-lysine acetylation The acetylation of the N-terminal lysine of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0018076 GO:0018075 biolink:BiologicalProcess peptidyl-phenylalanine bromination The bromination of phenylalanine. RESID:AA0176|RESID:AA0175|RESID:AA0174 go-plus.json http://purl.obolibrary.org/obo/GO_0018075 GO:0033694 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.5.7.- go-plus.json http://purl.obolibrary.org/obo/GO_0033694 GO:0018078 biolink:BiologicalProcess peptidyl-thyronine iodination The iodination of peptidyl-thyronine, formed from tyrosine. RESID:AA0178|RESID:AA0177 go-plus.json http://purl.obolibrary.org/obo/GO_0018078 GO:0033693 biolink:BiologicalProcess neurofilament bundle assembly The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules. go-plus.json NF bundle assembly http://purl.obolibrary.org/obo/GO_0033693 GO:0033692 biolink:BiologicalProcess cellular polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell. go-plus.json cellular polysaccharide anabolism|cellular polysaccharide synthesis|cellular polysaccharide formation|cellular polysaccharide biosynthesis|cellular glycan biosynthetic process|cellular glycan biosynthesis http://purl.obolibrary.org/obo/GO_0033692 GO:0018077 biolink:BiologicalProcess protein iodination The addition of one or more iodine atoms to an amino acid residue in a protein. go-plus.json protein amino acid iodination http://purl.obolibrary.org/obo/GO_0018077 GO:0018050 biolink:BiologicalProcess C-terminal peptidyl-threonine amidation The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein. RESID:AA0097 go-plus.json http://purl.obolibrary.org/obo/GO_0018050 CHEBI:73852 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73852 chebi_ph7_3 CHEBI:73851 biolink:ChemicalSubstance 1-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73851 chebi_ph7_3 GO:0018052 biolink:BiologicalProcess C-terminal peptidyl-tyrosine amidation The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein. RESID:AA0099 go-plus.json http://purl.obolibrary.org/obo/GO_0018052 GO:0018051 biolink:BiologicalProcess C-terminal peptidyl-tryptophan amidation The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein. RESID:AA0098 go-plus.json http://purl.obolibrary.org/obo/GO_0018051 CHEBI:73856 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73856 chebi_ph7_3 CHEBI:73858 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73858 chebi_ph7_3 GO:0033689 biolink:BiologicalProcess negative regulation of osteoblast proliferation Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. go-plus.json down-regulation of osteoblast proliferation|downregulation of osteoblast proliferation|down regulation of osteoblast proliferation|inhibition of osteoblast proliferation http://purl.obolibrary.org/obo/GO_0033689 CHEBI:73857 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73857 chebi_ph7_3 GO:0033680 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033680 CHEBI:58299 biolink:ChemicalSubstance 3-dehydrosphinganinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58299 chebi_ph7_3 CHEBI:58298 biolink:ChemicalSubstance 6-phosphonato-2-dehydro-3-deoxy-D-galactate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58298 chebi_ph7_3 CHEBI:58297 biolink:ChemicalSubstance glutathione disulfide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58297 chebi_ph7_3 CHEBI:58296 biolink:ChemicalSubstance 4-methyl-5-(2-phosphonatooxyethyl)thiazole(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58296 chebi_ph7_3 CHEBI:58295 biolink:ChemicalSubstance S-acetylcysteaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58295 chebi_ph7_3 CHEBI:58294 biolink:ChemicalSubstance beta-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(beta-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58294 chebi_ph7_3 CHEBI:58293 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_58293 chebi_ph7_3 CHEBI:58292 biolink:ChemicalSubstance (S)-naringenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58292 GO:0018047 biolink:BiologicalProcess C-terminal peptidyl-phenylalanine amidation The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein. RESID:AA0094 go-plus.json http://purl.obolibrary.org/obo/GO_0018047 GO:0033688 biolink:BiologicalProcess regulation of osteoblast proliferation Any process that modulates the frequency, rate or extent of osteoblast proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0033688 GO:0033687 biolink:BiologicalProcess osteoblast proliferation The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. go-plus.json http://purl.obolibrary.org/obo/GO_0033687 GO:0018046 biolink:BiologicalProcess C-terminal peptidyl-methionine amidation The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein. RESID:AA0093 go-plus.json http://purl.obolibrary.org/obo/GO_0018046 GO:0018049 biolink:BiologicalProcess C-terminal peptidyl-serine amidation The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein. RESID:AA0096 go-plus.json http://purl.obolibrary.org/obo/GO_0018049 GO:0033686 biolink:BiologicalProcess positive regulation of luteinizing hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone. go-plus.json up-regulation of luteinizing hormone secretion|upregulation of luteinizing hormone secretion|up regulation of luteinizing hormone secretion|activation of luteinizing hormone secretion|stimulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033686 GO:0033685 biolink:BiologicalProcess negative regulation of luteinizing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone. go-plus.json inhibition of luteinizing hormone secretion|down regulation of luteinizing hormone secretion|downregulation of luteinizing hormone secretion|down-regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033685 GO:0018048 biolink:BiologicalProcess C-terminal peptidyl-proline amidation The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein. RESID:AA0095 go-plus.json http://purl.obolibrary.org/obo/GO_0018048 GO:0018043 biolink:BiologicalProcess C-terminal peptidyl-isoleucine amidation The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein. RESID:AA0090 go-plus.json http://purl.obolibrary.org/obo/GO_0018043 GO:0033684 biolink:BiologicalProcess regulation of luteinizing hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0033684 GO:0018042 biolink:BiologicalProcess C-terminal peptidyl-histidine amidation The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein. RESID:AA0089 go-plus.json http://purl.obolibrary.org/obo/GO_0018042 GO:0033683 biolink:BiologicalProcess nucleotide-excision repair, DNA incision A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. go-plus.json DNA incision involved in nucleotide-excision repair|nucleic acid cleavage involved in nucleotide-excision repair http://purl.obolibrary.org/obo/GO_0033683 GO:0018045 biolink:BiologicalProcess C-terminal peptidyl-lysine amidation The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein. RESID:AA0092 go-plus.json http://purl.obolibrary.org/obo/GO_0018045 GO:0033682 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033682 CHEBI:73850 biolink:ChemicalSubstance 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73850 chebi_ph7_3 GO:0018044 biolink:BiologicalProcess C-terminal peptidyl-leucine amidation The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein. RESID:AA0091 go-plus.json http://purl.obolibrary.org/obo/GO_0018044 GO:0033681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033681 GO:0018061 biolink:BiologicalProcess peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid. RESID:AA0128 go-plus.json peptidyl-L-3-phenyllactic acid anabolism from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid synthesis from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid formation from peptidyl-phenylalanine http://purl.obolibrary.org/obo/GO_0018061 CHEBI:73863 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73863 chebi_ph7_3 GO:0018060 biolink:BiologicalProcess N-terminal peptidyl-cysteine deamination The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue. go-plus.json http://purl.obolibrary.org/obo/GO_0018060 CHEBI:73862 biolink:ChemicalSubstance (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73862 chebi_ph7_3 GO:0018063 biolink:BiologicalProcess cytochrome c-heme linkage The linkage of cytochromes and other heme proteins to heme. RESID:AA0135|RESID:AA0134 go-plus.json cytochrome c-haem linkage http://purl.obolibrary.org/obo/GO_0018063 GO:0018062 biolink:BiologicalProcess peptidyl-tryptophan succinylation The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan. RESID:AA0130 go-plus.json http://purl.obolibrary.org/obo/GO_0018062 GO:0033679 biolink:MolecularActivity 3'-5' DNA/RNA helicase activity Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis. go-plus.json 3' to 5' DNA/RNA helicase activity|ATP-dependent 3' to 5' DNA/RNA helicase activity|ATP-dependent 3'-5' DNA/RNA helicase activity http://purl.obolibrary.org/obo/GO_0033679 GO:0033678 biolink:MolecularActivity 5'-3' DNA/RNA helicase activity Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis. Reactome:R-HSA-163120 go-plus.json 5' to 3' DNA/RNA helicase activity|ATP-dependent 5'-3' DNA/RNA helicase activity|ATP-dependent 5' to 3' DNA/RNA helicase activity http://purl.obolibrary.org/obo/GO_0033678 CHEBI:58291 biolink:ChemicalSubstance 1D-1-guanidiniumyl-1-deoxy-3-dehydro-scyllo-inositol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58291 chebi_ph7_3 CHEBI:58290 biolink:ChemicalSubstance trypanothione(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58290 chebi_ph7_3 CHEBI:58287 biolink:ChemicalSubstance heparosan-N-sulfate D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58287 chebi_ph7_3 CHEBI:58286 biolink:ChemicalSubstance methyl-CoM(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58286 chebi_ph7_3 CHEBI:58285 biolink:ChemicalSubstance 7-methylguanosine 5'-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58285 chebi_ph7_3 CHEBI:58284 biolink:ChemicalSubstance 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58284 chebi_ph7_3 CHEBI:58283 biolink:ChemicalSubstance CDP-4-dehydro-3,6-dideoxy-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58283 chebi_ph7_3 CHEBI:58282 biolink:ChemicalSubstance 1D-myo-inositol 1,4-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58282 chebi_ph7_3 GO:0033677 biolink:MolecularActivity DNA/RNA helicase activity Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis. go-plus.json ATP-dependent DNA/RNA helicase activity http://purl.obolibrary.org/obo/GO_0033677 GO:0018058 biolink:BiologicalProcess N-terminal protein amino acid deamination, from amino carbon The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol. RESID:AA0129|RESID:AA0128|RESID:AA0127 go-plus.json http://purl.obolibrary.org/obo/GO_0018058 GO:0018057 biolink:BiologicalProcess peptidyl-lysine oxidation The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens. RESID:AA0121 go-plus.json http://purl.obolibrary.org/obo/GO_0018057 GO:0033676 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033676 GO:0033675 biolink:CellularComponent pericanalicular vesicle A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes. go-plus.json http://purl.obolibrary.org/obo/GO_0033675 GO:0033674 biolink:BiologicalProcess positive regulation of kinase activity Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. go-plus.json kinase activator|up regulation of kinase activity|stimulation of kinase activity|up-regulation of kinase activity|upregulation of kinase activity http://purl.obolibrary.org/obo/GO_0033674 GO:0018059 biolink:BiologicalProcess N-terminal peptidyl-serine deamination The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue. go-plus.json http://purl.obolibrary.org/obo/GO_0018059 GO:0033673 biolink:BiologicalProcess negative regulation of kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. go-plus.json down regulation of kinase activity|downregulation of kinase activity|kinase inhibitor|down-regulation of kinase activity|inhibition of kinase activity http://purl.obolibrary.org/obo/GO_0033673 GO:0018054 biolink:BiologicalProcess peptidyl-lysine biotinylation The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine. RESID:AA0117 go-plus.json http://purl.obolibrary.org/obo/GO_0018054 GO:0033672 biolink:BiologicalProcess positive regulation of NAD+ kinase activity Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. go-plus.json upregulation of NAD+ kinase activity|stimulation of NAD+ kinase activity|up-regulation of NAD+ kinase activity|NAD+ kinase activator|up regulation of NAD+ kinase activity http://purl.obolibrary.org/obo/GO_0033672 GO:0018053 biolink:BiologicalProcess C-terminal peptidyl-valine amidation The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein. RESID:AA0100 go-plus.json http://purl.obolibrary.org/obo/GO_0018053 GO:0033671 biolink:BiologicalProcess negative regulation of NAD+ kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. go-plus.json downregulation of NAD+ kinase activity|NAD+ kinase inhibitor|down regulation of NAD+ kinase activity|inhibition of NAD+ kinase activity|down-regulation of NAD+ kinase activity http://purl.obolibrary.org/obo/GO_0033671 GO:0018056 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018056 GO:0033670 biolink:BiologicalProcess regulation of NAD+ kinase activity Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. go-plus.json NAD kinase regulator|regulation of NAD kinase activity http://purl.obolibrary.org/obo/GO_0033670 GO:0018055 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0018055 CHEBI:58289 biolink:ChemicalSubstance 2-phosphonato-D-glycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58289 chebi_ph7_3 CHEBI:73874 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_73874 CHEBI:73873 biolink:ChemicalSubstance 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_73873 chebi_ph7_3 GO:0018030 biolink:MolecularActivity peptidyl-lysine N6-myristoyltransferase activity Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0018030 CHEBI:73876 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_73876 GO:0033669 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0033669 GO:0033668 biolink:BiologicalProcess negative regulation by symbiont of host apoptotic process Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host apoptosis|downregulation by organism of host apoptotic programmed cell death|down regulation by organism of host apoptotic programmed cell death|inhibition by organism of host apoptotic programmed cell death|down-regulation by organism of host apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0033668 GO:0033667 biolink:BiologicalProcess obsolete negative regulation of growth or development of symbiont in host OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json down-regulation of growth or development of organism within host|negative regulation of growth or development of symbiont in host|negative regulation of invasive growth|negative regulation of growth or development of symbiont within host|inhibition of growth of development of organism within host|down regulation of growth or development of organism within host|downregulation of growth or development of organism within host http://purl.obolibrary.org/obo/GO_0033667 CHEBI:58280 biolink:ChemicalSubstance IDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58280 chebi_ph7_3 CHEBI:58277 biolink:ChemicalSubstance dehydro-D-arabinono-1,4-lactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58277 chebi_ph7_3 CHEBI:58276 biolink:ChemicalSubstance 4-hydroxy-4-methyl-2-oxoglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58276 chebi_ph7_3 CHEBI:58275 biolink:ChemicalSubstance 2-methylserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58275 chebi_ph7_3 CHEBI:58274 biolink:ChemicalSubstance L-gamma-glutamyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58274 chebi_ph7_3 CHEBI:58273 biolink:ChemicalSubstance aldehydo-D-ribose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58273 chebi_ph7_3 GO:0018029 biolink:BiologicalProcess peptidyl-lysine palmitoylation The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine. RESID:AA0077 go-plus.json http://purl.obolibrary.org/obo/GO_0018029 GO:0018028 biolink:BiologicalProcess peptidyl-lysine myristoylation The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine. RESID:AA0078 go-plus.json peptidyl-lysine myristylation http://purl.obolibrary.org/obo/GO_0018028 CHEBI:58272 biolink:ChemicalSubstance 3-phosphonato-D-glycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58272 chebi_ph7_3 CHEBI:58270 biolink:ChemicalSubstance N-acetyl-L-leucinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58270 chebi_ph7_3 GO:0033666 biolink:BiologicalProcess obsolete positive regulation of growth or development of symbiont in host OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json positive regulation of growth or development of symbiont in host|positive regulation of invasive growth|positive regulation of growth or development of symbiont within host|up-regulation of growth or development of organism within host|upregulation of growth or development of organism within host|up regulation of growth or development of organism within host http://purl.obolibrary.org/obo/GO_0033666 GO:0018025 biolink:MolecularActivity calmodulin-lysine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine. RHEA:21556|EC:2.1.1.60|Reactome:R-HSA-6786205|MetaCyc:2.1.1.60-RXN go-plus.json S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity|S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity|S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity http://purl.obolibrary.org/obo/GO_0018025 GO:0033665 biolink:BiologicalProcess obsolete regulation of growth or development of symbiont in host OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. go-plus.json modulation of growth or development of organism within host|modulation of growth or development of symbiont within host|modulation of invasive growth|regulation of growth or development of symbiont in host|regulation of growth or development of symbiont within host http://purl.obolibrary.org/obo/GO_0033665 GO:0018024 biolink:MolecularActivity histone-lysine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives. Reactome:R-HSA-5637686|Reactome:R-HSA-5638332|Reactome:R-HSA-5649800|Reactome:R-HSA-4827382|Reactome:R-HSA-5423038|Reactome:R-HSA-5649802|Reactome:R-HSA-4827383|MetaCyc:HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN|Reactome:R-HSA-5649801|Reactome:R-HSA-3788748|RHEA:10024|Reactome:R-HSA-3788745|Reactome:R-HSA-5634729|Reactome:R-HSA-5651654|Reactome:R-HSA-5638141|Reactome:R-HSA-5634802|EC:2.1.1.354|Reactome:R-HSA-5649764|Reactome:R-HSA-5651657|RESID:AA0076|Reactome:R-HSA-5649799|RESID:AA0075|RESID:AA0074|Reactome:R-HSA-5159245|Reactome:R-HSA-5634750|Reactome:R-HSA-5638333|Reactome:R-HSA-5638157|Reactome:R-HSA-5244692 go-plus.json protein methylase III activity|histone-lysine N-methylase activity|S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity|S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity|protein methylase 3 activity|histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity|protein methyltransferase II activity|protein (lysine) methyltransferase activity http://purl.obolibrary.org/obo/GO_0018024 GO:0033664 biolink:BiologicalProcess obsolete positive regulation by symbiont of host defense-related protein level OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033664 GO:0018027 biolink:BiologicalProcess peptidyl-lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. RESID:AA0075 go-plus.json http://purl.obolibrary.org/obo/GO_0018027 GO:0018026 biolink:BiologicalProcess peptidyl-lysine monomethylation The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine. RESID:AA0076 go-plus.json http://purl.obolibrary.org/obo/GO_0018026 GO:0033663 biolink:BiologicalProcess obsolete negative regulation by symbiont of host defense-related protein level OBSOLETE. Any process in which the symbiont reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033663 GO:0018021 biolink:BiologicalProcess peptidyl-histidine methylation The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine). RESID:AA0317|RESID:AA0073 go-plus.json http://purl.obolibrary.org/obo/GO_0018021 CHEBI:73870 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73870 chebi_ph7_3 GO:0033662 biolink:BiologicalProcess obsolete modulation by symbiont of host defense-related protein level OBSOLETE. The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033662 GO:0033661 biolink:BiologicalProcess effector-mediated defense to host-produced reactive oxygen species A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of defense-related host respiratory burst|down regulation by organism of defense-related host metabolic burst|negative regulation by organism of defense-related host reactive oxygen intermediate production|negative regulation by organism of defense-related host ROI production|negative regulation by organism of defense-related host reactive oxidative species production|down-regulation by organism of defense-related host oxidative burst|negative regulation by organism of defense-related host ROS production|negative regulation by symbiont of defense-related host reactive oxygen species production|suppression by symbiont of defense-related host reactive oxygen species production|downregulation by organism of defense-related host AOS production|inhibition by organism of defense-related host active oxygen species production http://purl.obolibrary.org/obo/GO_0033661 GO:0018020 biolink:BiologicalProcess peptidyl-glutamic acid methylation The addition of a methyl group to a glutamic acid residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018020 CHEBI:58279 biolink:ChemicalSubstance 3-(3,4-dihydroxyphenyl)lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_58279 chebi_ph7_3 GO:0033660 biolink:BiologicalProcess suppression by symbiont of host resistance gene-dependent defense response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json downregulation by symbiont of pathogen-race/host plant cultivar-specific resistance in symbiont|down regulation by symbiont of defense response in host by specific elicitors|suppression by symbiont of host resistance gene-dependent defense response|negative regulation by symbiont of host resistance gene-dependent defense response|inhibition by symbiont of host resistance gene-dependent defense response|down-regulation by symbiont of host gene-for-gene resistance http://purl.obolibrary.org/obo/GO_0033660 GO:0018023 biolink:BiologicalProcess peptidyl-lysine trimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine. RESID:AA0074 go-plus.json http://purl.obolibrary.org/obo/GO_0018023 CHEBI:73871 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73871 chebi_ph7_3 GO:0018022 biolink:BiologicalProcess peptidyl-lysine methylation The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative. go-plus.json http://purl.obolibrary.org/obo/GO_0018022 CHEBI:58278 biolink:ChemicalSubstance D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58278 chebi_ph7_3 GO:0018041 biolink:BiologicalProcess C-terminal peptidyl-glycine amidation The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein. RESID:AA0088 go-plus.json http://purl.obolibrary.org/obo/GO_0018041 CHEBI:73887 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_73887 GO:0018040 biolink:BiologicalProcess C-terminal peptidyl-glutamic acid amidation The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein. RESID:AA0087 go-plus.json http://purl.obolibrary.org/obo/GO_0018040 CHEBI:73886 biolink:ChemicalSubstance UDP-alpha-D-apiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_73886 GO:0033659 biolink:BiologicalProcess modification by symbiont of host mitochondrion The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033659 CHEBI:73888 biolink:ChemicalSubstance Gly-Asn go-plus.json http://purl.obolibrary.org/obo/CHEBI_73888 GO:0033658 biolink:BiologicalProcess modification by symbiont of host chloroplast thylakoid The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033658 GO:0033657 biolink:BiologicalProcess modification by symbiont of host chloroplast part The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033657 GO:0033656 biolink:BiologicalProcess modification by symbiont of host chloroplast The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033656 CHEBI:83203 biolink:ChemicalSubstance 1-stearoylglycerone 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83203 chebi_ph7_3 CHEBI:58266 biolink:ChemicalSubstance 5-hydroxy-L-tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58266 chebi_ph7_3 PR:000009978 biolink:Protein lactotransferrin A protein that is a translation product of the human LTF gene or a 1:1 ortholog thereof. go-plus.json LTF|LF|lactoferrin|talalactoferrin http://purl.obolibrary.org/obo/PR_000009978 CHEBI:58265 biolink:ChemicalSubstance 2-hydroxy-3-oxosuccinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58265 chebi_ph7_3 CHEBI:58264 biolink:ChemicalSubstance 4-ammoniobutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_58264 chebi_ph7_3 CHEBI:58263 biolink:ChemicalSubstance N-acetylputrescinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_58263 chebi_ph7_3 CHEBI:58262 biolink:ChemicalSubstance 2-C-methyl-D-erythritol 4-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58262 chebi_ph7_3 GO:0018039 biolink:BiologicalProcess C-terminal peptidyl-glutamine amidation The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein. RESID:AA0086 go-plus.json http://purl.obolibrary.org/obo/GO_0018039 CHEBI:58261 biolink:ChemicalSubstance methyl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_58261 chebi_ph7_3 CHEBI:58260 biolink:ChemicalSubstance N(6)-acetyl-L-lysine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58260 chebi_ph7_3 GO:0033655 biolink:CellularComponent host cell cytoplasm part Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json cytoplasm component http://purl.obolibrary.org/obo/GO_0033655 gocheck_do_not_annotate GO:0018036 biolink:BiologicalProcess C-terminal peptidyl-asparagine amidation The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein. RESID:AA0083 go-plus.json http://purl.obolibrary.org/obo/GO_0018036 GO:0018035 biolink:BiologicalProcess C-terminal peptidyl-arginine amidation The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein. RESID:AA0082 go-plus.json http://purl.obolibrary.org/obo/GO_0018035 GO:0033654 biolink:CellularComponent host cell chloroplast thylakoid membrane Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033654 GO:0033653 biolink:CellularComponent host cell chloroplast part Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json host chloroplast component http://purl.obolibrary.org/obo/GO_0033653 gocheck_do_not_annotate GO:0018038 biolink:BiologicalProcess C-terminal peptidyl-cysteine amidation The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein. RESID:AA0085 go-plus.json http://purl.obolibrary.org/obo/GO_0018038 GO:0033652 biolink:CellularComponent host cell chloroplast A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033652 GO:0018037 biolink:BiologicalProcess C-terminal peptidyl-aspartic acid amidation The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein. RESID:AA0084 go-plus.json http://purl.obolibrary.org/obo/GO_0018037 GO:0018032 biolink:BiologicalProcess protein amidation Addition of an amide group from a glycine to a protein amino acid. go-plus.json protein amino acid amidation http://purl.obolibrary.org/obo/GO_0018032 GO:0033651 biolink:CellularComponent host cell plastid Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0033651 GO:0018031 biolink:MolecularActivity peptidyl-lysine N6-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule. EC:2.3.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0018031 GO:0033650 biolink:CellularComponent host cell mitochondrion A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json host mitochondria http://purl.obolibrary.org/obo/GO_0033650 CHEBI:58269 biolink:ChemicalSubstance 2-amino-2-deoxy-D-gluconic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_58269 chebi_ph7_3 GO:0018034 biolink:BiologicalProcess C-terminal peptidyl-alanine amidation The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein. RESID:AA0081 go-plus.json http://purl.obolibrary.org/obo/GO_0018034 CHEBI:73883 biolink:ChemicalSubstance UDP-alpha-D-apiose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_73883 chebi_ph7_3 GO:0018033 biolink:BiologicalProcess protein C-terminal amidation The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein. go-plus.json http://purl.obolibrary.org/obo/GO_0018033 CHEBI:24803 biolink:ChemicalSubstance indole-3-acetic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_24803 CHEBI:24809 biolink:ChemicalSubstance indole-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24809 CHEBI:24810 biolink:ChemicalSubstance indol-3-yl carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24810 CHEBI:24814 biolink:ChemicalSubstance indole-3-methanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24814 chebi_ph7_3 CHEBI:24813 biolink:ChemicalSubstance 3-(indol-3-yl)lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24813 UBERON:0015482 biolink:AnatomicalEntity right hepatic artery A hepatic artery that is part of a right lobe of liver. go-plus.json right branch of hepatic artery proper|ramus dexter (arteria hepatica propria)|right part of hepatic artery proper http://purl.obolibrary.org/obo/UBERON_0015482 UBERON:0015485 biolink:AnatomicalEntity choledocho-duodenal junction hat part of the duodenal wall traversed by the ductus choledochus, ductus pancreaticus, and ampulla. go-plus.json choledochoduodenal junction http://purl.obolibrary.org/obo/UBERON_0015485 UBERON:0015481 biolink:AnatomicalEntity left hepatic artery A hepatic artery that is part of a left lobe of liver. go-plus.json ramus sinister (arteria hepatica propria)|left part of hepatic artery proper|left branch of hepatic artery http://purl.obolibrary.org/obo/UBERON_0015481 CHEBI:2424 biolink:ChemicalSubstance acetylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2424 CHEBI:73801 biolink:ChemicalSubstance Gly-Glu go-plus.json http://purl.obolibrary.org/obo/CHEBI_73801 CHEBI:73803 biolink:ChemicalSubstance Ala-Asp go-plus.json http://purl.obolibrary.org/obo/CHEBI_73803 CHEBI:73802 biolink:ChemicalSubstance 1-nitrocyclohexene go-plus.json http://purl.obolibrary.org/obo/CHEBI_73802 chebi_ph7_3 GO:0008608 biolink:BiologicalProcess attachment of spindle microtubules to kinetochore The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex. go-plus.json kinetochore-microtubule interaction|microtubule and chromosome interaction|amphotelic attachment|spindle-chromosome interaction|attachment of spindle microtubules to chromosome|bipolar attachment|spindle chromosome attachment|kinetochore microtubule interaction|kinetochore-microtubule attachment|microtubule and kinetochore interaction|microtubule anchoring at kinetochore|microtubule capture|spindle kinetochore attachment http://purl.obolibrary.org/obo/GO_0008608 GO:0008607 biolink:MolecularActivity phosphorylase kinase regulator activity Modulation of the activity of the enzyme phosphorylase kinase. EC:2.7.1.- go-plus.json phosphorylase kinase, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0008607 CHEBI:48851 biolink:ChemicalSubstance methoxynaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48851 GO:0008606 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008606 CHEBI:48854 biolink:ChemicalSubstance sulfurous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48854 GO:0008605 biolink:MolecularActivity obsolete protein kinase CK2 regulator activity OBSOLETE. Modulation of the activity of the enzyme protein kinase CK2. go-plus.json protein kinase CK2, intrinsic regulator activity|protein kinase CK2 regulator activity|casein kinase II, regulator http://purl.obolibrary.org/obo/GO_0008605 GO:0008604 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008604 GO:0008603 biolink:MolecularActivity cAMP-dependent protein kinase regulator activity Modulation of the activity of the enzyme cAMP-dependent protein kinase. go-plus.json cAMP-dependent protein kinase, intrinsic regulator activity|3',5'-cAMP-dependent protein kinase regulator activity|adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity|cyclic AMP-dependent protein kinase regulator activity|3',5' cAMP-dependent protein kinase regulator activity http://purl.obolibrary.org/obo/GO_0008603 CHEBI:48855 biolink:ChemicalSubstance sulfino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_48855 GO:0008602 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008602 GO:0008601 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008601 GO:0008600 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0008600 CHEBI:48850 biolink:ChemicalSubstance alkyloxynaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_48850 CHEBI:83172 biolink:ChemicalSubstance N-tetracosenoylsphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_83172 chebi_ph7_3 CHEBI:83171 biolink:ChemicalSubstance (2E,4Z)-2-hydroxy-7-methyl-6-oxo-2,4-octadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_83171 CHEBI:83170 biolink:ChemicalSubstance (3R)-3-amino-3-phenylpropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_83170 GO:0008609 biolink:MolecularActivity alkylglycerone-phosphate synthase activity Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion. EC:2.5.1.26|MetaCyc:ALKYLGLYCERONE-PHOSPHATE-SYNTHASE-RXN|RHEA:36171|Reactome:R-HSA-390427 go-plus.json alkyldihydroxyacetonephosphate synthase activity|1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity|alkyl-DHAP|DHAP-AT|alkyl DHAP synthetase activity|alkyl-DHAP synthase activity|dihydroxyacetone-phosphate acyltransferase activity|alkyldihydroxyacetone phosphate synthetase activity http://purl.obolibrary.org/obo/GO_0008609 GO:0008619 biolink:MolecularActivity obsolete RHEB small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json RHEB small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0008619 GO:0008618 biolink:BiologicalProcess 7-methylguanosine metabolic process The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA. go-plus.json 7-methylguanosine metabolism http://purl.obolibrary.org/obo/GO_0008618 GO:0008617 biolink:BiologicalProcess guanosine metabolic process The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution. go-plus.json guanosine metabolism http://purl.obolibrary.org/obo/GO_0008617 GO:0008616 biolink:BiologicalProcess queuosine biosynthetic process The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. go-plus.json queuosine biosynthesis|queuosine anabolism|queuosine synthesis|queuosine formation http://purl.obolibrary.org/obo/GO_0008616 GO:0008615 biolink:BiologicalProcess pyridoxine biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. go-plus.json pyridoxine formation|pyridoxine biosynthesis|pyridoxine anabolism|pyridoxine synthesis http://purl.obolibrary.org/obo/GO_0008615 GO:0008614 biolink:BiologicalProcess pyridoxine metabolic process The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json pyridoxine metabolism http://purl.obolibrary.org/obo/GO_0008614 CHEBI:24899 biolink:ChemicalSubstance isoleucine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_24899 GO:0008613 biolink:MolecularActivity diuretic hormone activity The action characteristic of a diuretic hormone, a peptide hormone that, upon receptor binding, regulates water balance and fluid secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0008613 CHEBI:24898 biolink:ChemicalSubstance isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24898 CHEBI:48847 biolink:ChemicalSubstance heterocyclic fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_48847 GO:0008612 biolink:BiologicalProcess peptidyl-lysine modification to peptidyl-hypusine The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine. RESID:AA0116 go-plus.json hypusine biosynthetic process from peptidyl-lysine|hypusinylation|hypusine anabolism|hypusine synthesis|hypusine formation from peptidyl-lysine|hypusine formation|hypusine synthesis from peptidyl-lysine|protein hypusination|hypusine anabolism from peptidyl-lysine|hypusine biosynthetic process|hypusine biosynthesis http://purl.obolibrary.org/obo/GO_0008612 CHEBI:24897 biolink:ChemicalSubstance isoindoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_24897 GO:0008611 biolink:BiologicalProcess ether lipid biosynthetic process The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol. go-plus.json ether lipid biosynthesis|ether lipid anabolism|ether lipid synthesis|plasmalogen biosynthetic process|ether lipid formation http://purl.obolibrary.org/obo/GO_0008611 GO:0008610 biolink:BiologicalProcess lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. go-plus.json lipid synthesis|lipid formation|lipid biosynthesis|lipid anabolism|lipogenesis http://purl.obolibrary.org/obo/GO_0008610 UBERON:0015420 biolink:AnatomicalEntity ureteral valve A valve that is part of a ureter. go-plus.json valve or ureter|ureteral valve http://purl.obolibrary.org/obo/UBERON_0015420 CHEBI:83189 biolink:ChemicalSubstance phosphatidylinositol monophosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83189 CHEBI:10221 biolink:ChemicalSubstance alpha-copaene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10221 chebi_ph7_3 UBERON:0015418 biolink:AnatomicalEntity urethra mesenchymal layer A mesenchyme that is part of a urethra. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015418 CHEBI:2468 biolink:ChemicalSubstance secondary alpha-hydroxy ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_2468 chebi_ph7_3 CHEBI:10223 biolink:ChemicalSubstance alpha-cryptoxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_10223 chebi_ph7_3 CHEBI:48848 biolink:ChemicalSubstance erythronolide A go-plus.json http://purl.obolibrary.org/obo/CHEBI_48848 chebi_ph7_3 CHEBI:24863 biolink:ChemicalSubstance iodophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24863 CHEBI:24862 biolink:ChemicalSubstance iodoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24862 CHEBI:24860 biolink:ChemicalSubstance iodine molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_24860 CHEBI:24867 biolink:ChemicalSubstance monoatomic ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_24867 CHEBI:24866 biolink:ChemicalSubstance salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_24866 CHEBI:24865 biolink:ChemicalSubstance iodotyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24865 CHEBI:24864 biolink:ChemicalSubstance iodothyronine go-plus.json http://purl.obolibrary.org/obo/CHEBI_24864 UBERON:0015410 biolink:AnatomicalEntity heart plus pericardium go-plus.json heart/pericardium http://purl.obolibrary.org/obo/UBERON_0015410 CHEBI:83195 biolink:ChemicalSubstance glycerophosphoglycerophosphate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_83195 CHEBI:83193 biolink:ChemicalSubstance phosphatidylinositol trisphosphate(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83193 CHEBI:83191 biolink:ChemicalSubstance phosphatidylinositol bisphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_83191 chebi_ph7_3 CHEBI:24869 biolink:ChemicalSubstance ionophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_24869 CHEBI:24868 biolink:ChemicalSubstance organic salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_24868 CHEBI:24874 biolink:ChemicalSubstance iron ionophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_24874 CHEBI:24873 biolink:ChemicalSubstance iron molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_24873 CHEBI:24875 biolink:ChemicalSubstance iron cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_24875 chebi_ph7_3 CHEBI:24870 biolink:ChemicalSubstance ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_24870 CHEBI:2448 biolink:ChemicalSubstance actinorhodin go-plus.json http://purl.obolibrary.org/obo/CHEBI_2448 CHEBI:48828 biolink:ChemicalSubstance cobalt(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_48828 chebi_ph7_3 UBERON:0015474 biolink:AnatomicalEntity axilla skin A zone of skin that is part of a axilla. go-plus.json skin of axilla|axillary skin http://purl.obolibrary.org/obo/UBERON_0015474 CHEBI:24844 biolink:ChemicalSubstance inosines go-plus.json http://purl.obolibrary.org/obo/CHEBI_24844 CHEBI:24843 biolink:ChemicalSubstance inosine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24843 OBO:GOCHE_50427 biolink:OntologyClass substance with platelet aggregation inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_50427 3_STAR UBERON:0015476 biolink:AnatomicalEntity nose skin A zone of skin that is part of a external nose. go-plus.json external nasal skin|skin of external nose|skin of nose http://purl.obolibrary.org/obo/UBERON_0015476 UBERON:0015477 biolink:AnatomicalEntity axillary fat pad A fat pad that is part of a axilla. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015477 CHEBI:2490 biolink:ChemicalSubstance 6-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2490 CHEBI:24848 biolink:ChemicalSubstance inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_24848 chebi_ph7_3 CHEBI:24846 biolink:ChemicalSubstance inositol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24846 CHEBI:48819 biolink:ChemicalSubstance cyano group go-plus.json http://purl.obolibrary.org/obo/CHEBI_48819 chebi_ph7_3 CHEBI:2495 biolink:ChemicalSubstance adrenosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_2495 chebi_ph7_3 CHEBI:24852 biolink:ChemicalSubstance insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24852 CHEBI:24850 biolink:ChemicalSubstance insect attractant go-plus.json http://purl.obolibrary.org/obo/CHEBI_24850 CHEBI:24853 biolink:ChemicalSubstance intercalator go-plus.json http://purl.obolibrary.org/obo/CHEBI_24853 CHEBI:24859 biolink:ChemicalSubstance iodine atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_24859 chebi_ph7_3 CHEBI:24823 biolink:ChemicalSubstance indoleacetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_24823 CHEBI:24821 biolink:ChemicalSubstance indolyl carbohydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24821 UBERON:0015458 biolink:AnatomicalEntity mediastinal fat pad A fat pad that is part of a mediastinum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015458 CHEBI:10216 biolink:ChemicalSubstance cedr-8-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_10216 chebi_ph7_3 UBERON:0015454 biolink:AnatomicalEntity pancreatic fat pad A fat pad that is part of a pancreas. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015454 UBERON:0015453 biolink:AnatomicalEntity subcutaneous lymph node A lymph node that is part of a hypodermis. go-plus.json http://purl.obolibrary.org/obo/UBERON_0015453 CHEBI:2479 biolink:ChemicalSubstance adenosylcobinamide guanosyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_2479 CHEBI:10213 biolink:ChemicalSubstance alpha-amyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_10213 chebi_ph7_3 CHEBI:24829 biolink:ChemicalSubstance indolones go-plus.json http://purl.obolibrary.org/obo/CHEBI_24829 CHEBI:24828 biolink:ChemicalSubstance indoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_24828 CHEBI:24834 biolink:ChemicalSubstance inorganic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_24834 CHEBI:24833 biolink:ChemicalSubstance oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_24833 CHEBI:24838 biolink:ChemicalSubstance inorganic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_24838 CHEBI:24837 biolink:ChemicalSubstance inorganic peroxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24837 CHEBI:2481 biolink:ChemicalSubstance adenosylcobinamide phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_2481 CHEBI:24836 biolink:ChemicalSubstance inorganic oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_24836 CHEBI:2480 biolink:ChemicalSubstance adenosylcobinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_2480 chebi_ph7_3 CHEBI:24835 biolink:ChemicalSubstance inorganic molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_24835 CHEBI:2483 biolink:ChemicalSubstance adenosylcobyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_2483 CHEBI:2482 biolink:ChemicalSubstance adenosylcob(III)yrinic acid a,c-diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_2482 CHEBI:24839 biolink:ChemicalSubstance inorganic salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_24839 UBERON:0022248 biolink:AnatomicalEntity cerebral nerve fasciculus go-plus.json telencephalic nerve fascicle|cerebral fascicle|nerve fascicle of telencephalon|cerebral fasciculus|telencephalic fascicle http://purl.obolibrary.org/obo/UBERON_0022248 CHEBI:25214 biolink:ChemicalSubstance metal-sulfur cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_25214 CHEBI:25213 biolink:ChemicalSubstance metal cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25213 chebi_ph7_3 CHEBI:25212 biolink:ChemicalSubstance metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_25212 CHEBI:25219 biolink:ChemicalSubstance methacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25219 CHEBI:25218 biolink:ChemicalSubstance methacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25218 chebi_ph7_3 CHEBI:25216 biolink:ChemicalSubstance metalloporphyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25216 CHEBI:15889 biolink:ChemicalSubstance sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15889 chebi_ph7_3 CHEBI:15888 biolink:ChemicalSubstance 5-oxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15888 CHEBI:15885 biolink:ChemicalSubstance L-2-amino-4-chloropent-4-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15885 CHEBI:15884 biolink:ChemicalSubstance tropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15884 CHEBI:15887 biolink:ChemicalSubstance 5-aminopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15887 CHEBI:15886 biolink:ChemicalSubstance UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15886 CHEBI:15881 biolink:ChemicalSubstance 2-oxopropyl-CoM go-plus.json http://purl.obolibrary.org/obo/CHEBI_15881 CHEBI:15880 biolink:ChemicalSubstance S-methyl 3-phospho-1-thio-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15880 UBERON:0022254 biolink:AnatomicalEntity ventral thalamic fasciculus The thalamic fasciculus is a component of the subthalamus. It is sometimes considered synonymous with 'field H1 of Forel'. Nerve fibres forming a composite bundle containing cerebellothalamic (crossed) and pallidothalamic (uncrossed) fibres that is insinuated between the thalamus and zona incerta. The thalamic fasciculus consists of the joint fibers of the ansa lenticularis and the lenticular fasciculus, coming from different portions of the medial globus pallidus, before they jointly enter the ventral lateral nucleus of the thalamus. go-plus.json campus foreli (pars dorsalis)|tegmental area h1|forelli campus I|fasciculus thalamicus hypothalami|thalamic fasciculus|area subthalamica tegmentalis, pars dorsomedialis|forel's field h1|area tegmentalis H1|fasciculus thalamicus [h1]|field H1|h1 bundle of Forel|fasciculus thalamicus|area tegmentalis, pars dorsalis (Forel)|area tegmentalis, pars dorsalis|h1 field of Forel|thalamic fasciculus [h1] http://purl.obolibrary.org/obo/UBERON_0022254 CHEBI:15883 biolink:ChemicalSubstance P(1),P(4)-bis(5'-guanosyl) tetraphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15883 CHEBI:15882 biolink:ChemicalSubstance phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15882 chebi_ph7_3 CHEBI:25224 biolink:ChemicalSubstance methanesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25224 chebi_ph7_3 CHEBI:25223 biolink:ChemicalSubstance methanesulfonate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_25223 chebi_ph7_3 CHEBI:15878 biolink:ChemicalSubstance 10-hydroxydihydrosanguinarine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15878 chebi_ph7_3 CHEBI:64834 biolink:ChemicalSubstance menaquinol-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64834 chebi_ph7_3 CHEBI:15877 biolink:ChemicalSubstance L-lupinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15877 CHEBI:64833 biolink:ChemicalSubstance 6-kestotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_64833 chebi_ph7_3 CHEBI:15874 biolink:ChemicalSubstance N(2)-malonyl-D-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15874 CHEBI:64838 biolink:ChemicalSubstance 1D-myo-inositol 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64838 CHEBI:64837 biolink:ChemicalSubstance N(pros)-phosphonato-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64837 chebi_ph7_3 CHEBI:15873 biolink:ChemicalSubstance alpha-D-glucosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15873 CHEBI:64836 biolink:ChemicalSubstance 6,6-kestotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_64836 chebi_ph7_3 CHEBI:64835 biolink:ChemicalSubstance 1,6-kestotetraose go-plus.json http://purl.obolibrary.org/obo/CHEBI_64835 chebi_ph7_3 CHEBI:15870 biolink:ChemicalSubstance betaine aldehyde hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15870 chebi_ph7_3 CHEBI:15871 biolink:ChemicalSubstance o-orsellinate depside go-plus.json http://purl.obolibrary.org/obo/CHEBI_15871 CHEBI:64839 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64839 chebi_ph7_3 CHEBI:64841 biolink:ChemicalSubstance 1D-myo-inositol 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64841 chebi_ph7_3 CHEBI:64840 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64840 chebi_ph7_3 UBERON:2000542 biolink:AnatomicalEntity medial column go-plus.json http://purl.obolibrary.org/obo/UBERON_2000542 CHEBI:64845 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64845 CHEBI:64844 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64844 CHEBI:64849 biolink:ChemicalSubstance glycyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_64849 CHEBI:64848 biolink:ChemicalSubstance N-acetyl-beta-muramate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64848 chebi_ph7_3 CHEBI:64847 biolink:ChemicalSubstance L-threonyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64847 chebi_ph7_3 CHEBI:64846 biolink:ChemicalSubstance glycyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64846 UBERON:0022279 biolink:AnatomicalEntity strand of hair on external ear go-plus.json hair of tragus|hair of external ear|tragus hair http://purl.obolibrary.org/obo/UBERON_0022279 OBO:cl#has_high_plasma_membrane_amount biolink:OntologyClass has_high_plasma_membrane_amount A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). has_high_plasma_membrane_amount go-plus.json http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount CHEBI:64851 biolink:ChemicalSubstance L-threonyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_64851 CHEBI:64850 biolink:ChemicalSubstance N-carbamoylaspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64850 CHEBI:64856 biolink:ChemicalSubstance N(epsilon)-GMP-N(alpha)-acetyl-L-lysine methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_64856 CHEBI:40822 biolink:ChemicalSubstance aldehydo-D-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_40822 chebi_ph7_3 CHEBI:15899 biolink:ChemicalSubstance (R)-5-diphosphomevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15899 CHEBI:64854 biolink:ChemicalSubstance N(alpha)-acetyl-L-lysine methyl ester(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64854 chebi_ph7_3 UBERON:2000523 biolink:AnatomicalEntity inferior reticular formation go-plus.json http://purl.obolibrary.org/obo/UBERON_2000523 CHEBI:64853 biolink:ChemicalSubstance N(epsilon)-(5'-guanylyl)-N(alpha)-acetyl-L-lysine methyl ester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64853 chebi_ph7_3 CHEBI:15896 biolink:ChemicalSubstance 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_15896 chebi_ph7_3 CHEBI:15895 biolink:ChemicalSubstance D-galactono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15895 chebi_ph7_3 CHEBI:64859 biolink:ChemicalSubstance N(alpha)-acetyl-L-lysine methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_64859 CHEBI:64858 biolink:ChemicalSubstance aminopropylcadaverine(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64858 chebi_ph7_3 CHEBI:15897 biolink:ChemicalSubstance N-(long-chain-acyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15897 chebi_ph7_3 UBERON:0022282 biolink:AnatomicalEntity secretion of Harderian gland A merocrine secretion that is produced by a Harderian gland, containing lipids go-plus.json Harderian gland fluid|Harderian gland secretion http://purl.obolibrary.org/obo/UBERON_0022282 CHEBI:64857 biolink:ChemicalSubstance cosmetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_64857 CHEBI:15892 biolink:ChemicalSubstance S-succinylglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_15892 CHEBI:15891 biolink:ChemicalSubstance taurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15891 UBERON:0022284 biolink:AnatomicalEntity lacrimal gland bud the single bud-like invagination of the conjunctival fornix epithelium at the temporal aspect of the eye that signals lacrimal gland formation (Int Rev Cytol. 1996;168:1-80. Cell biology of the harderian gland) go-plus.json http://purl.obolibrary.org/obo/UBERON_0022284 CHEBI:15894 biolink:ChemicalSubstance (2-trans,6-trans)-farnesal go-plus.json http://purl.obolibrary.org/obo/CHEBI_15894 chebi_ph7_3 UBERON:0022287 biolink:AnatomicalEntity tear film An aqueous substance that covers the anterior surface of the eyeball, keeping the cornea wet. go-plus.json precorneal film http://purl.obolibrary.org/obo/UBERON_0022287 CHEBI:15893 biolink:ChemicalSubstance 1-pyrroline-5-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15893 chebi_ph7_3 UBERON:0022286 biolink:AnatomicalEntity secretion of nictitans gland A secretion that is produced by a nictitans gland, containing glycoprotein go-plus.json nictitans gland secretion|nictitans gland fluid http://purl.obolibrary.org/obo/UBERON_0022286 UBERON:0022288 biolink:AnatomicalEntity surface of eyeball go-plus.json surface of region of wall of eyeball http://purl.obolibrary.org/obo/UBERON_0022288 CHEBI:15890 biolink:ChemicalSubstance 5,6-dimethylbenzimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_15890 chebi_ph7_3 NCBITaxon:3524 biolink:OrganismalEntity Caryophyllales go-plus.json Centrospermae http://purl.obolibrary.org/obo/NCBITaxon_3524 CHEBI:15849 biolink:ChemicalSubstance aryl(methyl)malonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15849 CHEBI:64863 biolink:ChemicalSubstance 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64863 chebi_ph7_3 CHEBI:15848 biolink:ChemicalSubstance dTDP-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15848 CHEBI:64862 biolink:ChemicalSubstance 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64862 chebi_ph7_3 CHEBI:64861 biolink:ChemicalSubstance 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64861 chebi_ph7_3 CHEBI:64860 biolink:ChemicalSubstance aminopropylcadaverine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64860 CHEBI:15845 biolink:ChemicalSubstance keto-L-tagatose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15845 CHEBI:15844 biolink:ChemicalSubstance 1D-myo-inositol 3,4,5,6-tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15844 CHEBI:64865 biolink:ChemicalSubstance 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64865 chebi_ph7_3 CHEBI:15847 biolink:ChemicalSubstance 2-(alpha-D-mannosyl)-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15847 CHEBI:15846 biolink:ChemicalSubstance NAD(+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15846 CHEBI:40813 biolink:ChemicalSubstance 4-methoxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_40813 CHEBI:64864 biolink:ChemicalSubstance 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64864 CHEBI:15841 biolink:ChemicalSubstance polypeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15841 CHEBI:15840 biolink:ChemicalSubstance N-acylneuraminic acid 9-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15840 CHEBI:64869 biolink:ChemicalSubstance 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64869 CHEBI:15843 biolink:ChemicalSubstance arachidonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15843 CHEBI:15842 biolink:ChemicalSubstance orotidine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15842 CHEBI:64868 biolink:ChemicalSubstance hexacosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64868 chebi_ph7_3 CHEBI:64870 biolink:ChemicalSubstance (S)-malyl N-acetyl-alpha-D-glucosaminide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64870 chebi_ph7_3 CHEBI:64874 biolink:ChemicalSubstance 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64874 chebi_ph7_3 CHEBI:15838 biolink:ChemicalSubstance (7R)-7-(5-carboxy-5-oxopentanamido)cephalosporanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15838 CHEBI:64873 biolink:ChemicalSubstance 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64873 CHEBI:15837 biolink:ChemicalSubstance isoamylol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15837 chebi_ph7_3 CHEBI:64872 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64872 chebi_ph7_3 CHEBI:64871 biolink:ChemicalSubstance (S)-malyl alpha-D-glucosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64871 chebi_ph7_3 CHEBI:15834 biolink:ChemicalSubstance 1-O-galloyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15834 chebi_ph7_3 CHEBI:88823 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_88823 CHEBI:15833 biolink:ChemicalSubstance sulcatol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15833 chebi_ph7_3 CHEBI:64877 biolink:ChemicalSubstance 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64877 CHEBI:64876 biolink:ChemicalSubstance bacillithiol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64876 chebi_ph7_3 CHEBI:15836 biolink:ChemicalSubstance 4-phospho-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15836 CHEBI:88824 biolink:ChemicalSubstance N-acetylcadaverine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88824 CHEBI:64875 biolink:ChemicalSubstance 1-hexadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64875 chebi_ph7_3 CHEBI:15835 biolink:ChemicalSubstance 1-acylglycerone 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15835 CHEBI:15830 biolink:ChemicalSubstance 8-amino-7-oxononanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15830 CHEBI:15832 biolink:ChemicalSubstance urea-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15832 chebi_ph7_3 CHEBI:15831 biolink:ChemicalSubstance geranylgeranyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15831 NCBITaxon:3502 biolink:OrganismalEntity Fagales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3502 CHEBI:64885 biolink:ChemicalSubstance C20 phytosphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64885 chebi_ph7_3 CHEBI:64884 biolink:ChemicalSubstance C20 phytosphingosine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64884 chebi_ph7_3 CHEBI:64883 biolink:ChemicalSubstance diacetylchitobiose-6'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64883 chebi_ph7_3 CHEBI:64882 biolink:ChemicalSubstance (S)-malyl N-acetyl-alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64882 CHEBI:15867 biolink:ChemicalSubstance D-xylono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15867 chebi_ph7_3 CHEBI:64889 biolink:ChemicalSubstance 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64889 CHEBI:15866 biolink:ChemicalSubstance 2-deoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15866 CHEBI:64888 biolink:ChemicalSubstance (S)-malyl alpha-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64888 CHEBI:64887 biolink:ChemicalSubstance C20 sphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64887 chebi_ph7_3 CHEBI:15868 biolink:ChemicalSubstance CDP-N-methylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15868 CHEBI:64886 biolink:ChemicalSubstance C20 sphinganine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64886 chebi_ph7_3 CHEBI:15862 biolink:ChemicalSubstance ethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15862 CHEBI:15865 biolink:ChemicalSubstance 6-phospho-2-dehydro-D-gluconate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15865 CHEBI:15864 biolink:ChemicalSubstance luteolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15864 CHEBI:15861 biolink:ChemicalSubstance trichodiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15861 chebi_ph7_3 CHEBI:15860 biolink:ChemicalSubstance N-methylhexanamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15860 chebi_ph7_3 UBERON:0022236 biolink:AnatomicalEntity peduncle of thalamus go-plus.json thalamic peduncle http://purl.obolibrary.org/obo/UBERON_0022236 UBERON:0022235 biolink:AnatomicalEntity peduncle of diencephalon go-plus.json diencephalon peduncle http://purl.obolibrary.org/obo/UBERON_0022235 CHEBI:74215 biolink:ChemicalSubstance 2-hydroxytetracosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74215 chebi_ph7_3 CHEBI:74214 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74214 chebi_ph7_3 NCBITaxon:2698737 biolink:OrganismalEntity Sar go-plus.json SAR supergroup http://purl.obolibrary.org/obo/NCBITaxon_2698737 CHEBI:74216 biolink:ChemicalSubstance N-(2-hydroxytetracosenoyl)sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74216 chebi_ph7_3 CHEBI:74218 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-1-diphospho-ditrans,polycis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74218 CHEBI:64891 biolink:ChemicalSubstance O-(pantetheine-4'-phosphoryl)serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64891 CHEBI:64890 biolink:ChemicalSubstance 1-hexadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64890 CHEBI:64896 biolink:ChemicalSubstance O-(pantetheine-4'-phosphoryl)serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64896 CHEBI:15859 biolink:ChemicalSubstance N-carbamoyl-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15859 CHEBI:64894 biolink:ChemicalSubstance [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64894 chebi_ph7_3 CHEBI:64893 biolink:ChemicalSubstance bornane-2,6-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_64893 chebi_ph7_3 CHEBI:64899 biolink:ChemicalSubstance [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64899 CHEBI:15855 biolink:ChemicalSubstance UDP-6-sulfoquinovose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15855 CHEBI:64898 biolink:ChemicalSubstance anionic amino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64898 CHEBI:15858 biolink:ChemicalSubstance bromide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15858 chebi_ph7_3 CHEBI:15857 biolink:ChemicalSubstance 5-L-glutamyl amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15857 CHEBI:64897 biolink:ChemicalSubstance diacetylchitobiose-6'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64897 CHEBI:15852 biolink:ChemicalSubstance aquacob(III)alamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15852 chebi_ph7_3 CHEBI:15851 biolink:ChemicalSubstance 3-(uracil-1-yl)-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15851 CHEBI:15854 biolink:ChemicalSubstance quinine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15854 CHEBI:15850 biolink:ChemicalSubstance 1-O-alkyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15850 chebi_ph7_3 UBERON:0022247 biolink:AnatomicalEntity forebrain ipsilateral fiber tracts go-plus.json FIFT http://purl.obolibrary.org/obo/UBERON_0022247 CHEBI:74213 biolink:ChemicalSubstance EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_74213 CHEBI:74212 biolink:ChemicalSubstance O-ureido-D-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74212 GO:0003953 biolink:MolecularActivity NAD+ nucleosidase activity Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose. Reactome:R-HSA-8938076|Reactome:R-HSA-8870346|RHEA:16301 go-plus.json NAD nucleosidase activity http://purl.obolibrary.org/obo/GO_0003953 CHEBI:50259 biolink:ChemicalSubstance beta-L-allofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50259 chebi_ph7_3 GO:0003952 biolink:MolecularActivity NAD+ synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate. Reactome:R-HSA-197271|EC:6.3.5.1|MetaCyc:NAD-SYNTH-GLN-RXN|RHEA:24384|Wikipedia:NAD+_synthase_(glutamine-hydrolysing) go-plus.json NAD+ synthetase (glutamine-hydrolyzing)|deamido-NAD+:L-glutamine amido-ligase (AMP-forming)|NAD(+) synthetase (glutamine-hydrolyzing) activity|desamidonicotinamide adenine dinucleotide amidotransferase activity|DPN synthetase activity|NAD+ synthase (glutamine-hydrolysing)|NAD synthase (glutamine-hydrolyzing) activity|nicotinamide adenine dinucleotide synthetase (glutamine) activity|NAD synthetase (glutamine-hydrolysing) http://purl.obolibrary.org/obo/GO_0003952 CHEBI:49269 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49269 GO:0003955 biolink:MolecularActivity NAD(P)H dehydrogenase (quinone) activity Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone. MetaCyc:NQOR-RXN|UM-BBD_reactionID:r0227|EC:1.6.5.2 go-plus.json NAD(P)H:quinone oxidoreductase activity|DT-diaphorase activity|NAD(P)H dehydrogenase activity|NAD(P)H-quinone dehydrogenase activity|quinone reductase activity|NAD(P)H:(quinone-acceptor)oxidoreductase activity|Naphthoquinone reductase activity|NAD(P)H: menadione oxidoreductase activity|diaphorase activity|phylloquinone reductase activity|vitamin-K reductase activity|reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity|reduced NAD(P)H dehydrogenase activity|QR1|dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity|viologen accepting pyridine nucleotide oxidoreductase activity|menadione reductase activity|naphthoquinone reductase activity|NAD(P)H-quinone oxidoreductase activity|NAD(P)H(2) dehydrogenase (quinone) activity|p-benzoquinone reductase activity|azoreductase activity|NAD(P)H2 dehydrogenase (quinone)|vitamin K reductase activity|NAD(P)H menadione reductase activity|menadione oxidoreductase activity|NADH-menadione reductase activity|NQO1|flavoprotein NAD(P)H-quinone reductase activity http://purl.obolibrary.org/obo/GO_0003955 CHEBI:50257 biolink:ChemicalSubstance L-allofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50257 chebi_ph7_3 GO:0003954 biolink:MolecularActivity NADH dehydrogenase activity Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor. RHEA:11356|MetaCyc:NADH-DEHYDROGENASE-RXN go-plus.json beta-NADH dehydrogenase dinucleotide activity|type I dehydrogenase activity|dihydrocodehydrogenase I dehydrogenase activity|DPNH diaphorase activity|NADH:cytochrome c oxidoreductase activity|NADH:(acceptor) oxidoreductase activity|diphosphopyrinase activity|NADH oxidoreductase activity|reduced diphosphopyridine nucleotide diaphorase activity|dihydronicotinamide adenine dinucleotide dehydrogenase activity|type 1 dehydrogenase activity|diaphorase activity|NADH diaphorase activity|NADH:acceptor oxidoreductase activity|NADH-menadione oxidoreductase activity|NADH hydrogenase activity|diphosphopyridine diaphorase activity|cytochrome c reductase activity|NADH2 dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003954 CHEBI:50256 biolink:ChemicalSubstance beta-D-allofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50256 chebi_ph7_3 GO:0003951 biolink:MolecularActivity NAD+ kinase activity Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+). Reactome:R-HSA-197198|KEGG_REACTION:R00104|RHEA:18629|EC:2.7.1.23|Reactome:R-HSA-8955030|MetaCyc:NAD-KIN-RXN go-plus.json NADK|nicotinamide adenine dinucleotide kinase (phosphorylating)|ATP:NAD+ 2'-phosphotransferase activity|DPN kinase activity|nicotinamide adenine dinucleotide kinase activity|NAD kinase activity http://purl.obolibrary.org/obo/GO_0003951 GO:0003950 biolink:MolecularActivity NAD+ ADP-ribosyltransferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor. Reactome:R-HSA-2187325|Reactome:R-HSA-9694773|Reactome:R-HSA-8938073|EC:2.4.2.30|Reactome:R-HSA-5651723|Reactome:R-HSA-5687653|Reactome:R-HSA-5688276|Reactome:R-HSA-8948800|Reactome:R-HSA-9686061|MetaCyc:NAD+-ADP-RIBOSYLTRANSFERASE-RXN|Reactome:R-HSA-3640858 go-plus.json NAD ADP-ribosyltransferase activity|ADP-ribosyltransferase (polymerizing) activity|poly(ADP-ribose)polymerase activity|poly(ADP-ribose) synthase activity|poly(adenosine diphosphate ribose) polymerase activity|poly(ADP-ribose) synthetase activity|NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity http://purl.obolibrary.org/obo/GO_0003950 CHEBI:49262 biolink:ChemicalSubstance cyclohexa-1,5-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49262 CHEBI:49261 biolink:ChemicalSubstance 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_49261 GO:1904679 biolink:BiologicalProcess myo-inositol import across plasma membrane The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json myo-inositol import into cell http://purl.obolibrary.org/obo/GO_1904679 CHEBI:49264 biolink:ChemicalSubstance nonatrienedicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49264 GO:1904678 biolink:MolecularActivity alpha-aminoacyl-tRNA binding Binding to an alpha-aminoacyl-tRNA. go-plus.json aminoacyl-tRNA binding http://purl.obolibrary.org/obo/GO_1904678 CHEBI:49263 biolink:ChemicalSubstance (S)-beta-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49263 chebi_ph7_3 GO:1904677 biolink:BiologicalProcess positive regulation of somatic stem cell division Any process that activates or increases the frequency, rate or extent of somatic stem cell division. go-plus.json upregulation of somatic stem cell renewal|up-regulation of somatic stem cell division|activation of somatic stem cell division|up regulation of somatic stem cell renewal|positive regulation of somatic stem cell renewal|activation of somatic stem cell renewal|up regulation of somatic stem cell division|up-regulation of somatic stem cell renewal|upregulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_1904677 CHEBI:49266 biolink:ChemicalSubstance (R)-beta-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49266 chebi_ph7_3 GO:1904676 biolink:BiologicalProcess negative regulation of somatic stem cell division Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division. go-plus.json down regulation of somatic stem cell renewal|downregulation of somatic stem cell renewal|down-regulation of somatic stem cell division|down-regulation of somatic stem cell renewal|negative regulation of somatic stem cell renewal|downregulation of somatic stem cell division|inhibition of somatic stem cell renewal|down regulation of somatic stem cell division|inhibition of somatic stem cell division http://purl.obolibrary.org/obo/GO_1904676 CHEBI:49265 biolink:ChemicalSubstance 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49265 GO:1904675 biolink:BiologicalProcess regulation of somatic stem cell division Any process that modulates the frequency, rate or extent of somatic stem cell division. go-plus.json regulation of somatic stem cell renewal http://purl.obolibrary.org/obo/GO_1904675 CHEBI:25297 biolink:ChemicalSubstance methylenetetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25297 CHEBI:49268 biolink:ChemicalSubstance 5-amino-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49268 GO:1904674 biolink:BiologicalProcess positive regulation of somatic stem cell population maintenance Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance. go-plus.json up regulation of somatic stem cell population maintenance|upregulation of somatic stem cell population maintenance|activation of somatic stem cell population maintenance|up-regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904674 GO:1904684 biolink:BiologicalProcess negative regulation of metalloendopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity. go-plus.json inhibition of metalloendoprotease activity|inhibition of metalloendopeptidase activity|down-regulation of metalloendoproteinase activity|negative regulation of metalloendoproteinase activity|down-regulation of metalloendoprotease activity|down regulation of metalloendopeptidase activity|downregulation of metalloendoproteinase activity|negative regulation of metalloendoprotease activity|downregulation of metalloendopeptidase activity|down regulation of metalloendoproteinase activity|downregulation of metalloendoprotease activity|down regulation of metalloendoprotease activity|inhibition of metalloendoproteinase activity|down-regulation of metalloendopeptidase activity http://purl.obolibrary.org/obo/GO_1904684 GO:1904683 biolink:BiologicalProcess regulation of metalloendopeptidase activity Any process that modulates the frequency, rate or extent of metalloendopeptidase activity. go-plus.json regulation of metalloendoproteinase activity|regulation of metalloendoprotease activity http://purl.obolibrary.org/obo/GO_1904683 GO:1904682 biolink:BiologicalProcess cellular response to 3-methylcholanthrene Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904682 GO:1904681 biolink:BiologicalProcess response to 3-methylcholanthrene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904681 GO:1904680 biolink:MolecularActivity peptide transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other. Reactome:R-HSA-1500817 go-plus.json peptide uptake permease activity|peptide transporter activity http://purl.obolibrary.org/obo/GO_1904680 CHEBI:49271 biolink:ChemicalSubstance (5xi,7xi,10xi)-eudesma-4(14),11-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49271 chebi_ph7_3 CHEBI:49270 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxochola-4,6-dien-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49270 CHEBI:50250 biolink:ChemicalSubstance (4R,7S)-7-isopropyl-4-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50250 chebi_ph7_3 GO:0003957 biolink:MolecularActivity NAD(P)+ transhydrogenase (B-specific) activity Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+. MetaCyc:PYRNUTRANSHYDROGEN-RXN|EC:1.6.1.1 go-plus.json NAD transhydrogenase|pyridine nucleotide transhydrogenase activity|H+-thase|NADH transhydrogenase|nicotinamide nucleotide transhydrogenase activity|non-energy-linked transhydrogenase activity|NADPH-NAD oxidoreductase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|NADH-NADP-transhydrogenase|NAD(P) transhydrogenase (B-specific) activity|NADPH:NAD+ oxidoreductase (B-specific)|NADPH:NAD+ transhydrogenase|NADPH-NAD transhydrogenase|pyridine nucleotide transferase http://purl.obolibrary.org/obo/GO_0003957 GO:0003956 biolink:MolecularActivity NAD(P)+-protein-arginine ADP-ribosyltransferase activity Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. EC:2.4.2.31|Reactome:R-HSA-1972385|MetaCyc:2.4.2.31-RXN go-plus.json protein-arginine ADP-ribosyltransferase activity|mono(ADPribosyl)transferase activity|NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity|mono(ADP-ribosyl)transferase activity|NAD(+):L-arginine ADP-D-ribosyltransferase activity|NAD(P)-arginine ADP-ribosyltransferase activity|peptidyl-arginine ADP-ribosylation activity|NAD+:L-arginine ADP-D-ribosyltransferase activity|NAD(P)+:L-arginine ADP-D-ribosyltransferase activity|NAD(P)(+)--arginine ADP-ribosyltransferase activity|ADP-ribosyltransferase activity|NAD(P)+-arginine ADP-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0003956 CHEBI:50254 biolink:ChemicalSubstance D-allofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50254 chebi_ph7_3 GO:0003959 biolink:MolecularActivity NADPH dehydrogenase activity Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor. UM-BBD_enzymeID:e0523|MetaCyc:NADPH-DEHYDROGENASE-RXN|EC:1.6.99.1|Reactome:R-HSA-9018901|Reactome:R-HSA-9018867|Reactome:R-HSA-9027632|RHEA:13149|Reactome:R-HSA-9027625|Reactome:R-HSA-9027631 go-plus.json NADPH:(acceptor) oxidoreductase activity|NADPH-dehydrogenase activity|NADPH2-dehydrogenase activity|triphosphopyridine diaphorase activity|TPNH-diaphorase activity|NADPH2 diaphorase activity|NADPH diaphorase activity|OYE|NADPH:acceptor oxidoreductase activity|triphosphopyridine nucleotide diaphorase activity|dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity|old yellow enzyme|reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity|TPNH dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003959 CHEBI:50253 biolink:ChemicalSubstance allofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50253 GO:0003958 biolink:MolecularActivity NADPH-hemoprotein reductase activity Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein. Reactome:R-HSA-76494|MetaCyc:NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN|EC:1.6.2.4|RHEA:24040 go-plus.json NADPH--ferrihemoprotein reductase activity|TPNH-cytochrome c reductase activity|TPNH(2) cytochrome c reductase activity|NADPH--ferricytochrome c oxidoreductase activity|cytochrome P-450 reductase activity|POR|NADPH--cytochrome P450 oxidoreductase activity|NADP--cytochrome reductase activity|reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|NADPH-cytochrome p-450 reductase activity|NADPH--cytochrome P450 reductase activity|NADPH:P-450 reductase activity|NADPH:hemoprotein oxidoreductase activity|NADP--cytochrome c reductase activity|NADPH-ferrihemoprotein reductase activity|NADPH:cytochrome c reductase activity|NADPH:P450 reductase activity|CPR activity|NADPH:cytochrome P450 reductase activity|NADPH-dependent cytochrome c reductase activity|cytochrome P450 reductase activity|NADPH:ferrihemoprotein oxidoreductase activity|dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|ferrihemoprotein P-450 reductase activity|NADPH--cytochrome c reductase activity|cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity|FAD-cytochrome c reductase activity|TPNH2 cytochrome c reductase activity|aldehyde reductase (NADPH-dependent) activity|NADPH--cytochrome c oxidoreductase activity|NADPH-cytochrome P-450 oxidoreductase activity|reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity http://purl.obolibrary.org/obo/GO_0003958 GO:0003964 biolink:MolecularActivity RNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Reactome:R-HSA-164504|MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN|Reactome:R-HSA-164520|EC:2.7.7.49 go-plus.json DNA nucleotidyltransferase (RNA-directed) activity|RT|RNA-instructed DNA polymerase activity|RNA-directed DNA polymerase, group II intron encoded|revertase activity|RNA revertase activity|RNA-dependent DNA polymerase activity|RNA-dependent deoxyribonucleate nucleotidyltransferase activity|reverse transcriptase activity|RNA-directed DNA polymerase, transposon encoded|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity http://purl.obolibrary.org/obo/GO_0003964 CHEBI:49259 biolink:ChemicalSubstance (2S)-2-[(R)-1-carboxyethylamino]pentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49259 CHEBI:50248 biolink:ChemicalSubstance hematologic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50248 GO:0003963 biolink:MolecularActivity RNA-3'-phosphate cyclase activity Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate. RHEA:23976|MetaCyc:RNA-3-PHOSPHATE-CYCLASE-RXN|EC:6.5.1.4 go-plus.json RNA 3'-terminal phosphate cyclase activity|RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)|RNA cyclase activity http://purl.obolibrary.org/obo/GO_0003963 CHEBI:50247 biolink:ChemicalSubstance antidote go-plus.json http://purl.obolibrary.org/obo/CHEBI_50247 CHEBI:49258 biolink:ChemicalSubstance (2R,3R)-2,3-dihydroxy-3-methylpentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49258 chebi_ph7_3 GO:0003966 biolink:MolecularActivity obsolete RNA-directed DNA polymerase, transposon encoded OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo. go-plus.json RNA-directed DNA polymerase, transposon encoded http://purl.obolibrary.org/obo/GO_0003966 CHEBI:50246 biolink:ChemicalSubstance 1-hydroxylimonen-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50246 chebi_ph7_3 CHEBI:50245 biolink:ChemicalSubstance (1R,4S)-1-hydroxylimonen-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50245 chebi_ph7_3 GO:0003960 biolink:MolecularActivity NADPH:quinone reductase activity Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone. Reactome:R-HSA-6799722|MetaCyc:QOR-RXN|EC:1.6.5.5|RHEA:14269 go-plus.json quinone oxidoreductase activity|zeta-crystallin activity|NADPH:quinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0003960 GO:0003962 biolink:MolecularActivity cystathionine gamma-synthase activity Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate. MetaCyc:O-SUCCHOMOSERLYASE-RXN|EC:2.5.1.48|RHEA:20397 go-plus.json cystathionine synthase activity|cystathionine g-synthase activity|O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity|O-succinylhomoserine synthetase activity|CTT gamma synthase activity|homoserine O-transsuccinylase activity|O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity|homoserine transsuccinylase activity|cystathionine synthetase activity|O-succinyl-L-homoserine (thiol)-lyase activity|cystathionine gamma synthase activity|O-succinylhomoserine synthase activity|O-succinylhomoserine (thiol)-lyase activity|O-succinyl-L-homoserine succinate-lyase activity http://purl.obolibrary.org/obo/GO_0003962 GO:0003961 biolink:MolecularActivity O-acetylhomoserine aminocarboxypropyltransferase activity Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers. MetaCyc:O-ACETYLHOMOSERINE-THIOL-LYASE-RXN|EC:2.5.1.49|RHEA:10048 go-plus.json L-methionine synthesis, direct, from O-acetyl-L-homoserine|O-acetylhomoserine sulfhydrolase activity|L-methionine formation, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity|O-acetyl-L-homoserine sulfhydrolase activity|L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine|methionine biosynthetic process, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity|OAH sulfhydrylase activity|O-acetylhomoserine (thiol)-lyase activity|L-methionine anabolism, direct, from O-acetyl-L-homoserine http://purl.obolibrary.org/obo/GO_0003961 CHEBI:50249 biolink:ChemicalSubstance anticoagulant go-plus.json http://purl.obolibrary.org/obo/CHEBI_50249 GO:0062240 biolink:MolecularActivity euchromatin-nuclear membrane anchor activity Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization. go-plus.json nuclear membrane-euchromatin tether activity|nuclear membrane-euchromatin anchor activity|euchromatin-nuclear membrane tether activity http://purl.obolibrary.org/obo/GO_0062240 CHEBI:49253 biolink:ChemicalSubstance (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49253 GO:1904689 biolink:BiologicalProcess negative regulation of cytoplasmic translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation. go-plus.json downregulation of cytoplasmic translational initiation|down regulation of cytoplasmic translational initiation|inhibition of cytoplasmic translational initiation|down-regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904689 CHEBI:49252 biolink:ChemicalSubstance 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_49252 chebi_ph7_3 GO:1904688 biolink:BiologicalProcess regulation of cytoplasmic translational initiation Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation. go-plus.json http://purl.obolibrary.org/obo/GO_1904688 GO:0062242 biolink:CellularComponent double membrane vesicle viral factory membrane One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory. go-plus.json membrane of double membrane vesicle viral factory http://purl.obolibrary.org/obo/GO_0062242 CHEBI:49255 biolink:ChemicalSubstance N-(6-aminohexanoyl)-6-aminohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49255 GO:1904687 biolink:BiologicalProcess positive regulation of mitotic spindle disassembly Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly. go-plus.json up-regulation of spindle breakdown during mitosis|up regulation of spindle disassembly during mitosis|activation of spindle breakdown during mitosis|up-regulation of mitotic spindle breakdown|up regulation of mitotic spindle disassembly|activation of mitotic spindle disassembly|upregulation of mitotic spindle catabolism|up-regulation of spindle degradation during mitosis|activation of spindle degradation during mitosis|upregulation of mitotic spindle degradation|upregulation of spindle disassembly during mitosis|positive regulation of spindle breakdown during mitosis|upregulation of mitotic spindle breakdown|up regulation of spindle breakdown during mitosis|up-regulation of mitotic spindle catabolism|up-regulation of mitotic spindle disassembly|activation of mitotic spindle catabolism|up regulation of mitotic spindle degradation|positive regulation of spindle degradation during mitosis|positive regulation of mitotic spindle degradation|up regulation of spindle degradation during mitosis|activation of mitotic spindle degradation|up-regulation of spindle disassembly during mitosis|activation of spindle disassembly during mitosis|up regulation of mitotic spindle breakdown|positive regulation of mitotic spindle breakdown|activation of mitotic spindle breakdown|upregulation of spindle breakdown during mitosis|upregulation of mitotic spindle disassembly|positive regulation of mitotic spindle catabolism|up regulation of mitotic spindle catabolism|upregulation of spindle degradation during mitosis|up-regulation of mitotic spindle degradation|positive regulation of spindle disassembly during mitosis http://purl.obolibrary.org/obo/GO_1904687 GO:0062241 biolink:MolecularActivity double strand break-nuclear membrane anchor activity Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair. go-plus.json DNA repair factory http://purl.obolibrary.org/obo/GO_0062241 CHEBI:49254 biolink:ChemicalSubstance (S,S)-9,10-dihydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49254 GO:1904686 biolink:BiologicalProcess regulation of mitotic spindle disassembly Any process that modulates the frequency, rate or extent of mitotic spindle disassembly. go-plus.json regulation of mitotic spindle catabolism|regulation of spindle disassembly during mitosis|regulation of mitotic spindle degradation|regulation of mitotic spindle breakdown|regulation of spindle breakdown during mitosis|regulation of spindle degradation during mitosis http://purl.obolibrary.org/obo/GO_1904686 GO:0062244 biolink:CellularComponent double membrane vesicle viral factory lumen The volume surrounded by the inner membrane of a double membrane vesicle viral factory. go-plus.json lumen of double membrane vesicle viral factory http://purl.obolibrary.org/obo/GO_0062244 CHEBI:49257 biolink:ChemicalSubstance (R)-3-hydroxy-3-methyl-2-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49257 chebi_ph7_3 GO:1904685 biolink:BiologicalProcess positive regulation of metalloendopeptidase activity Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity. go-plus.json upregulation of metalloendoprotease activity|up-regulation of metalloendoproteinase activity|up-regulation of metalloendopeptidase activity|up-regulation of metalloendoprotease activity|activation of metalloendoproteinase activity|positive regulation of metalloendoproteinase activity|activation of metalloendoprotease activity|upregulation of metalloendopeptidase activity|up regulation of metalloendoproteinase activity|positive regulation of metalloendoprotease activity|up regulation of metalloendoprotease activity|up regulation of metalloendopeptidase activity|activation of metalloendopeptidase activity|upregulation of metalloendoproteinase activity http://purl.obolibrary.org/obo/GO_1904685 CHEBI:49256 biolink:ChemicalSubstance (S)-2-acetyl-2-hydroxybutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49256 chebi_ph7_3 GO:0062243 biolink:CellularComponent double membrane vesicle viral factory outer membrane The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory. go-plus.json outer membrane of double membrane vesicle viral factory http://purl.obolibrary.org/obo/GO_0062243 GO:0062246 biolink:CellularComponent exocytic vesicle lumen The volume enclosed by an exocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0062246 GO:1904695 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle contraction Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction. go-plus.json up regulation of vascular smooth muscle contraction|upregulation of vascular smooth muscle contraction|positive regulation of vascular smooth muscle contraction|up-regulation of vascular smooth muscle contraction|activation of vascular smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904695 GO:1904694 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction. go-plus.json down-regulation of vascular smooth muscle contraction|downregulation of vascular smooth muscle contraction|down regulation of vascular smooth muscle contraction|inhibition of vascular smooth muscle contraction|negative regulation of vascular smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904694 GO:0062245 biolink:CellularComponent double membrane vesicle viral factory inner membrane The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory. go-plus.json inner membrane of double membrane vesicle viral factory http://purl.obolibrary.org/obo/GO_0062245 GO:1904693 biolink:BiologicalProcess midbrain morphogenesis The developmental process by which a midbrain is generated and organized. go-plus.json MB morphogenesis|mesencephalon morphogenesis http://purl.obolibrary.org/obo/GO_1904693 GO:0062248 biolink:BiologicalProcess cleistothecium formation The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. go-plus.json http://purl.obolibrary.org/obo/GO_0062248 GO:1904692 biolink:BiologicalProcess positive regulation of type B pancreatic cell proliferation Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation. go-plus.json up regulation of type B pancreatic cell proliferation|up regulation of pancreatic beta cell proliferation|upregulation of pancreatic B cell proliferation|upregulation of type B pancreatic cell proliferation|upregulation of pancreatic beta cell proliferation|up regulation of pancreatic B cell proliferation|activation of pancreatic B cell proliferation|positive regulation of pancreatic B cell proliferation|up-regulation of type B pancreatic cell proliferation|up-regulation of pancreatic beta cell proliferation|activation of type B pancreatic cell proliferation|activation of pancreatic beta cell proliferation|up-regulation of pancreatic B cell proliferation|positive regulation of pancreatic beta cell proliferation http://purl.obolibrary.org/obo/GO_1904692 GO:0062247 biolink:CellularComponent chloroplast vesicle A intracellular vesicle that is part of a chloroplast. go-plus.json http://purl.obolibrary.org/obo/GO_0062247 GO:1904691 biolink:BiologicalProcess negative regulation of type B pancreatic cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation. go-plus.json downregulation of pancreatic beta cell proliferation|downregulation of type B pancreatic cell proliferation|down regulation of pancreatic beta cell proliferation|down regulation of type B pancreatic cell proliferation|down regulation of pancreatic B cell proliferation|inhibition of type B pancreatic cell proliferation|inhibition of pancreatic beta cell proliferation|downregulation of pancreatic B cell proliferation|down-regulation of pancreatic B cell proliferation|negative regulation of pancreatic B cell proliferation|negative regulation of pancreatic beta cell proliferation|down-regulation of type B pancreatic cell proliferation|down-regulation of pancreatic beta cell proliferation|inhibition of pancreatic B cell proliferation http://purl.obolibrary.org/obo/GO_1904691 GO:1904690 biolink:BiologicalProcess positive regulation of cytoplasmic translational initiation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation. go-plus.json up regulation of cytoplasmic translational initiation|upregulation of cytoplasmic translational initiation|up-regulation of cytoplasmic translational initiation|activation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904690 CHEBI:49260 biolink:ChemicalSubstance 4-(L-gamma-glutamylamino)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49260 GO:0003968 biolink:MolecularActivity RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. EC:2.7.7.48|Reactome:R-HSA-9682465|Reactome:R-HSA-9681840|Reactome:R-HSA-168280|Reactome:R-HSA-9682563|Reactome:R-HSA-9694792|Reactome:R-HSA-192832|Reactome:R-HSA-9694605|Reactome:R-HSA-9694506|Reactome:R-HSA-9685639|Reactome:R-HSA-9694581|Reactome:R-HSA-192624|Reactome:R-HSA-192916|Reactome:R-HSA-9681674|Reactome:R-HSA-9694344|Reactome:R-HSA-9681651|Reactome:R-HSA-168301|Reactome:R-HSA-9685681|Reactome:R-HSA-9694277|MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-9694549|Reactome:R-HSA-192851 go-plus.json RNA-dependent RNA replicase activity|RNA-dependent RNA polymerase activity|RNA replicase activity|3D polymerase activity|ribonucleic replicase activity|RNA nucleotidyltransferase (RNA-directed) activity|Q-beta replicase activity|RNA-dependent ribonucleate nucleotidyltransferase activity|phage f2 replicase|ribonucleic acid-dependent ribonucleic acid polymerase activity|transcriptase|ribonucleic acid replicase activity|ribonucleic synthetase activity|PB1 proteins|RNA-directed RNA polymerase activity|polymerase L|PB2 proteins|RDRP|RNA synthetase activity|ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed) http://purl.obolibrary.org/obo/GO_0003968 CHEBI:50244 biolink:ChemicalSubstance (1R,2R,4S)-limonene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50244 chebi_ph7_3 CHEBI:50243 biolink:ChemicalSubstance 7-isopropyl-4-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50243 chebi_ph7_3 GO:0003967 biolink:MolecularActivity obsolete RNA-directed DNA polymerase, group II intron encoded OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo. go-plus.json RNA-directed DNA polymerase, group II intron encoded http://purl.obolibrary.org/obo/GO_0003967 GO:0003969 biolink:MolecularActivity obsolete RNA editase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json RNA editase activity http://purl.obolibrary.org/obo/GO_0003969 GO:0003931 biolink:MolecularActivity obsolete Rho small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Any member of the Rho subfamily of the RAS superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton. go-plus.json Rho small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0003931 CHEBI:49248 biolink:ChemicalSubstance ionone go-plus.json http://purl.obolibrary.org/obo/CHEBI_49248 GO:0003930 biolink:MolecularActivity obsolete RAS small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json RAS small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0003930 CHEBI:49247 biolink:ChemicalSubstance apo carotenoid monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49247 GO:0003933 biolink:MolecularActivity GTP cyclohydrolase activity Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. go-plus.json http://purl.obolibrary.org/obo/GO_0003933 CHEBI:50235 biolink:ChemicalSubstance (+)-dihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50235 chebi_ph7_3 CHEBI:49249 biolink:ChemicalSubstance beta-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49249 chebi_ph7_3 GO:0003932 biolink:MolecularActivity obsolete SAR small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json SAR small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0003932 CHEBI:50239 biolink:ChemicalSubstance epsilon-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50239 CHEBI:50238 biolink:ChemicalSubstance 4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50238 chebi_ph7_3 CHEBI:49240 biolink:ChemicalSubstance alpha-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49240 chebi_ph7_3 CHEBI:25273 biolink:ChemicalSubstance methyladenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25273 CHEBI:25272 biolink:ChemicalSubstance methyladenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25272 CHEBI:49242 biolink:ChemicalSubstance (E)-alpha-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49242 chebi_ph7_3 CHEBI:25271 biolink:ChemicalSubstance methyl-branched fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_25271 CHEBI:25270 biolink:ChemicalSubstance methyl myo-inositols go-plus.json http://purl.obolibrary.org/obo/CHEBI_25270 GO:1904699 biolink:BiologicalProcess positive regulation of acinar cell proliferation Any process that activates or increases the frequency, rate or extent of acinar cell proliferation. go-plus.json upregulation of acinic cell proliferation|up regulation of acinar cell proliferation|activation of acinar cell proliferation|upregulation of acinous cell proliferation|up regulation of acinic cell proliferation|positive regulation of acinic cell proliferation|activation of acinic cell proliferation|up-regulation of acinar cell proliferation|up-regulation of acinous cell proliferation|activation of acinous cell proliferation|upregulation of acinar cell proliferation|up-regulation of acinic cell proliferation|positive regulation of acinous cell proliferation|up regulation of acinous cell proliferation http://purl.obolibrary.org/obo/GO_1904699 CHEBI:49244 biolink:ChemicalSubstance (E,S)-alpha-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49244 chebi_ph7_3 GO:1904698 biolink:BiologicalProcess negative regulation of acinar cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation. go-plus.json downregulation of acinous cell proliferation|down regulation of acinic cell proliferation|down regulation of acinous cell proliferation|inhibition of acinous cell proliferation|down-regulation of acinar cell proliferation|downregulation of acinic cell proliferation|inhibition of acinar cell proliferation|down-regulation of acinic cell proliferation|negative regulation of acinic cell proliferation|inhibition of acinic cell proliferation|down-regulation of acinous cell proliferation|negative regulation of acinous cell proliferation|down regulation of acinar cell proliferation|downregulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_1904698 CHEBI:49243 biolink:ChemicalSubstance (E,R)-alpha-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49243 chebi_ph7_3 GO:1904697 biolink:BiologicalProcess regulation of acinar cell proliferation Any process that modulates the frequency, rate or extent of acinar cell proliferation. go-plus.json regulation of acinous cell proliferation|regulation of acinic cell proliferation http://purl.obolibrary.org/obo/GO_1904697 CHEBI:25275 biolink:ChemicalSubstance methylaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_25275 GO:1904696 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904696 CHEBI:25274 biolink:ChemicalSubstance methylamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_25274 CHEBI:25280 biolink:ChemicalSubstance methylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25280 GO:0003939 biolink:MolecularActivity L-iditol 2-dehydrogenase activity Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Reactome:R-HSA-5652195|MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.14|RHEA:10160 go-plus.json sorbitol dehydrogenase activity|glucitol dehydrogenase activity|NAD-sorbitol dehydrogenase|L-iditol:NAD oxidoreductase activity|NAD+-dependent sorbitol dehydrogenase activity|L-iditol:NAD+ 5-oxidoreductase activity|L-iditol (sorbitol) dehydrogenase activity|polyol dehydrogenase activity|NAD-dependent sorbitol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003939 GO:0003938 biolink:MolecularActivity IMP dehydrogenase activity Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+. Reactome:R-HSA-73794|RHEA:11708|MetaCyc:IMP-DEHYDROG-RXN|EC:1.1.1.205 go-plus.json inosinate dehydrogenase activity|inosine 5'-monophosphate dehydrogenase activity|inosine monophosphate oxidoreductase activity|inosine monophosphate dehydrogenase activity|IMP oxidoreductase activity|inosinic acid dehydrogenase activity|IMP:NAD+ oxidoreductase activity|inosine-5'-phosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003938 CHEBI:50233 biolink:ChemicalSubstance (+)-isodihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50233 chebi_ph7_3 GO:0003935 biolink:MolecularActivity GTP cyclohydrolase II activity Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+). RHEA:23704|KEGG_REACTION:R00425|EC:3.5.4.25|MetaCyc:GTP-CYCLOHYDRO-II-RXN go-plus.json GTP-8-formylhydrolase activity|guanosine triphosphate cyclohydrolase II|GTP 7,8-8,9-dihydrolase (diphosphate-forming) http://purl.obolibrary.org/obo/GO_0003935 GO:0003934 biolink:MolecularActivity GTP cyclohydrolase I activity Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate. MetaCyc:GTP-CYCLOHYDRO-I-RXN|KEGG_REACTION:R00424|EC:3.5.4.16|Reactome:R-HSA-1474146|RHEA:17473 go-plus.json GTP 8-formylhydrolase activity|guanosine triphosphate cyclohydrolase activity|guanosine triphosphate 8-deformylase activity|GTP 7,8-8,9-dihydrolase activity|dihydroneopterin triphosphate synthase activity http://purl.obolibrary.org/obo/GO_0003934 CHEBI:50232 biolink:ChemicalSubstance (+)-neoisodihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50232 chebi_ph7_3 GO:0003937 biolink:MolecularActivity IMP cyclohydrolase activity Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide. MetaCyc:IMPCYCLOHYDROLASE-RXN|Reactome:R-HSA-73797|EC:3.5.4.10|RHEA:18445 go-plus.json IMP synthetase activity|IMP 1,2-hydrolase (decyclizing)|inosinate cyclohydrolase activity|inosinicase activity http://purl.obolibrary.org/obo/GO_0003937 GO:0003936 biolink:MolecularActivity obsolete hydrogen-transporting two-sector ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). go-plus.json proton-transporting two-sector ATPase activity|hydrogen-transporting two-sector ATPase activity http://purl.obolibrary.org/obo/GO_0003936 GO:0003942 biolink:MolecularActivity N-acetyl-gamma-glutamyl-phosphate reductase activity Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+. MetaCyc:N-ACETYLGLUTPREDUCT-RXN|EC:1.2.1.38|RHEA:21588 go-plus.json NAGSA dehydrogenase activity|N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|N-acetyl-glutamate semialdehyde dehydrogenase activity|N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)|reductase, acetyl-gamma-glutamyl phosphate|N-acetylglutamate 5-semialdehyde dehydrogenase activity|N-acetylglutamic gamma-semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003942 CHEBI:49237 biolink:ChemicalSubstance gamma-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49237 chebi_ph7_3 CHEBI:50226 biolink:ChemicalSubstance 7-methyl-GTP(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50226 GO:0003941 biolink:MolecularActivity L-serine ammonia-lyase activity Catalysis of the reaction: L-serine = pyruvate + NH3. MetaCyc:4.3.1.17-RXN|RHEA:19169|EC:4.3.1.17 go-plus.json L-serine deaminase activity|serine deaminase activity|L-serine dehydratase activity|L-hydroxyaminoacid dehydratase activity|L-serine dehydration activity|L-serine ammonia-lyase (pyruvate-forming) activity|L-serine hydro-lyase (deaminating) activity http://purl.obolibrary.org/obo/GO_0003941 GO:0003944 biolink:MolecularActivity N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose. RHEA:24372|MetaCyc:3.1.4.45-RXN|EC:3.1.4.45 go-plus.json lysosomal alpha-N-acetylglucosaminidase activity|alpha-N-acetylglucosaminyl phosphodiesterase activity|alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity|2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity|glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity|phosphodiester glycosidase activity http://purl.obolibrary.org/obo/GO_0003944 CHEBI:49239 biolink:ChemicalSubstance (E)-gamma-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49239 chebi_ph7_3 GO:0003943 biolink:MolecularActivity N-acetylgalactosamine-4-sulfatase activity Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. Reactome:R-HSA-2282889|Reactome:R-HSA-1606789|Reactome:R-HSA-1793207|Wikipedia:Arylsulfatase_B|MetaCyc:3.1.6.12-RXN|Reactome:R-HSA-9036065|EC:3.1.6.12 go-plus.json arylsulfatase B|N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity|acetylgalactosamine 4-sulfatase activity|N-acetylgalactosamine-4-sulphatase activity|N-acetylgalactosamine 4-sulfate sulfohydrolase activity|chondroitinsulfatase http://purl.obolibrary.org/obo/GO_0003943 CHEBI:49238 biolink:ChemicalSubstance (Z)-gamma-bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49238 chebi_ph7_3 CHEBI:25289 biolink:ChemicalSubstance methylcatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25289 CHEBI:50229 biolink:ChemicalSubstance Schiff base go-plus.json http://purl.obolibrary.org/obo/CHEBI_50229 GO:0003940 biolink:MolecularActivity L-iduronidase activity Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate. Reactome:R-HSA-9036037|Reactome:R-HSA-1678716|Reactome:R-HSA-1793186|MetaCyc:3.2.1.76-RXN|Reactome:R-HSA-2206299|Reactome:R-HSA-9036041|Reactome:R-HSA-2090037|EC:3.2.1.76 go-plus.json glycosaminoglycan alpha-L-iduronohydrolase activity|alpha-L-iduronidase activity http://purl.obolibrary.org/obo/GO_0003940 CHEBI:49231 biolink:ChemicalSubstance sibirene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49231 chebi_ph7_3 CHEBI:25282 biolink:ChemicalSubstance methylbutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_25282 CHEBI:25281 biolink:ChemicalSubstance methylbenzyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25281 CHEBI:49235 biolink:ChemicalSubstance bisabolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49235 CHEBI:25286 biolink:ChemicalSubstance methylbutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_25286 GO:0003949 biolink:MolecularActivity 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. RHEA:15469|KEGG_REACTION:R04640|MetaCyc:PRIBFAICARPISOM-RXN|EC:5.3.1.16 go-plus.json phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity|N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity|1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity|N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity|phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity|1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity http://purl.obolibrary.org/obo/GO_0003949 NCBITaxon:3562 biolink:OrganismalEntity Spinacia oleracea go-plus.json Spinacea oleracea|spinach http://purl.obolibrary.org/obo/NCBITaxon_3562 NCBITaxon:3561 biolink:OrganismalEntity Spinacia go-plus.json Spinacea http://purl.obolibrary.org/obo/NCBITaxon_3561 GO:0003946 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003946 GO:0003945 biolink:MolecularActivity N-acetyllactosamine synthase activity Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine. RHEA:17745|MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN|EC:2.4.1.90 go-plus.json UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity|UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity|UDP-beta-1,4-galactosyltransferase activity|lactosamine synthase activity|NAL synthetase activity|UDP-galactose-acetylglucosamine galactosyltransferase activity|UDP-galactose-N-acetylglucosamine galactosyltransferase activity|UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity|Gal-T|UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity|UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|beta-1,4-GalT|lactosamine synthetase activity|beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity|lactose synthetase A protein|UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity|UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity|beta-(1,4)-galactosyltransferase activity|beta-1,4-galactosyltransferase activity|UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity|N-acetyllactosamine synthetase activity|acetyllactosamine synthetase activity|N-acetylglucosamine beta-(1,4)-galactosyltransferase activity|N-acetylglucosamine (beta-1,4)galactosyltransferase activity|UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0003945 GO:0003948 biolink:MolecularActivity N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+). RHEA:11544|KEGG_REACTION:R03421|MetaCyc:3.5.1.26-RXN|EC:3.5.1.26 go-plus.json 4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|glycosylasparaginase activity|aspartylglucosylaminase activity|glucosylamidase activity|aspartylglucosylaminidase activity|N-aspartyl-beta-glucosaminidase activity|aspartylglucosylamine deaspartylase activity|N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|aspartylglucosaminidase activity|aspartylglycosylamine amidohydrolase activity|beta-aspartylglucosylamine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0003948 GO:0003947 biolink:MolecularActivity (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide. RHEA:12588|EC:2.4.1.92|Reactome:R-HSA-8856223|MetaCyc:2.4.1.92-RXN go-plus.json GalNAc-T activity|uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|asialo-GM2 synthase activity|UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity|GM2 synthase activity|UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity|GM2/GD2-synthase activity|ganglioside GM2 synthase activity|UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity|beta-1,4N-aetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity|ganglioside GM3 acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity|UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0003947 CHEBI:50215 biolink:ChemicalSubstance dihydrocarveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50215 chebi_ph7_3 GO:0003911 biolink:MolecularActivity DNA ligase (NAD+) activity Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m). MetaCyc:DNA-LIGASE-NAD+-RXN|EC:6.5.1.2 go-plus.json DNA-joining enzyme|deoxyribonucleic-joining enzyme|polynucleotide ligase (NAD+) activity|deoxyribonucleate ligase|DNA ligase (NAD)|polynucleotide ligase (NAD(+)) activity|deoxyribonucleic repair enzyme|polynucleotide ligase (NAD)|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)|polynucleotide ligase (nicotinamide adenine dinucleotide)|DNA joinase activity|polynucleotide synthetase (nicotinamide adenine dinucleotide)|polydeoxyribonucleotide synthase (NAD+) activity|deoxyribonucleic ligase|polynucleotide ligase|DNA repair enzyme activity|deoxyribonucleic acid joinase|polynucleotide synthetase activity|Polydeoxyribonucleotide synthase (NAD(+)) activity|deoxyribonucleic acid ligase|polydeoxyribonucleotide synthase (NAD)|deoxyribonucleic joinase http://purl.obolibrary.org/obo/GO_0003911 GO:0003910 biolink:MolecularActivity DNA ligase (ATP) activity Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m). MetaCyc:DNA-LIGASE-ATP-RXN|EC:6.5.1.1 go-plus.json polydeoxyribonucleotide synthase (ATP) activity|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)|sealase activity|deoxyribonucleic-joining enzyme|deoxyribonucleic acid repair enzyme|deoxyribonucleic acid-joining enzyme|deoxyribonucleate ligase|deoxyribonucleic repair enzyme|polynucleotide ligase (ATP) activity|DNA joinase activity|deoxyribonucleic ligase|polynucleotide ligase|DNA repair enzyme activity|deoxyribonucleic acid joinase|deoxyribonucleic acid ligase|deoxyribonucleic joinase|DNA-joining enzyme http://purl.obolibrary.org/obo/GO_0003910 CHEBI:50218 biolink:ChemicalSubstance EC 3.1.4.* (phosphoric diester hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50218 CHEBI:25255 biolink:ChemicalSubstance methyl methanesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25255 chebi_ph7_3 CHEBI:49222 biolink:ChemicalSubstance (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49222 CHEBI:49224 biolink:ChemicalSubstance gamma-himachalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49224 chebi_ph7_3 CHEBI:25253 biolink:ChemicalSubstance methyl halides go-plus.json http://purl.obolibrary.org/obo/CHEBI_25253 CHEBI:49223 biolink:ChemicalSubstance 4-(2-carboxyphenyl)-2-oxobut-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49223 GO:0003917 biolink:MolecularActivity DNA topoisomerase type I (single strand cut, ATP-independent) activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle. MetaCyc:5.99.1.2-RXN|EC:5.6.2.1 go-plus.json topoisomerase|omega-protein activity|nicking-closing enzyme activity|swivelase activity|type I DNA topoisomerase activity|DNA topoisomerase I activity|deoxyribonucleate topoisomerase|untwisting enzyme activity|type I topoisomerase activity|relaxing enzyme activity http://purl.obolibrary.org/obo/GO_0003917 GO:0003916 biolink:MolecularActivity DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA. EC:5.6.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0003916 GO:0003919 biolink:MolecularActivity FMN adenylyltransferase activity Catalysis of the reaction: ATP + FMN = diphosphate + FAD. Reactome:R-HSA-196929|EC:2.7.7.2|MetaCyc:FADSYN-RXN|RHEA:17237|KEGG_REACTION:R00161 go-plus.json FAD pyrophosphorylase activity|FAD diphosphorylase activity|adenosine triphosphate-riboflavine mononucleotide transadenylase activity|riboflavine adenine dinucleotide adenylyltransferase activity|FAD synthetase activity|riboflavin adenine dinucleotide pyrophosphorylase activity|ATP:FMN adenylyltransferase activity|riboflavin mononucleotide adenylyltransferase activity|flavin adenine dinucleotide synthetase activity|adenosine triphosphate-riboflavin mononucleotide transadenylase activity http://purl.obolibrary.org/obo/GO_0003919 GO:0003918 biolink:MolecularActivity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2. MetaCyc:5.99.1.3-RXN|EC:5.6.2.2|Wikipedia:Type_II_topoisomerase go-plus.json DNA topoisomerase II activity|DNA topoisomerase type II activity|topoisomerase|deoxyribonucleate topoisomerase|DNA topoisomerase IV activity|topoisomerase II|DNA topoisomerase II|DNA topoisomerase (ATP-hydrolysing)|type II DNA topoisomerase activity|deoxyribonucleic topoisomerase activity http://purl.obolibrary.org/obo/GO_0003918 GO:0003913 biolink:MolecularActivity DNA photolyase activity Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA. MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0003913 CHEBI:50211 biolink:ChemicalSubstance retinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50211 chebi_ph7_3 GO:0003912 biolink:MolecularActivity DNA nucleotidylexotransferase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN|EC:2.7.7.31 go-plus.json nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|deoxyribonucleic acid nucleotidyltransferase activity|terminal addition enzyme activity|terminal deoxynucleotide transferase activity|terminal transferase activity|deoxyribonucleic nucleotidyltransferase activity|deoxynucleotidyl terminal transferase activity|TdT|terminal deoxynucleotidyltransferase activity|terminal deoxyribonucleotidyltransferase activity|addase activity http://purl.obolibrary.org/obo/GO_0003912 CHEBI:50210 biolink:ChemicalSubstance 7-methyl-GTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_50210 CHEBI:8478 biolink:ChemicalSubstance propanoyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_8478 GO:0003914 biolink:MolecularActivity DNA (6-4) photolyase activity Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA. EC:4.1.99.13|MetaCyc:RXN-10771 go-plus.json http://purl.obolibrary.org/obo/GO_0003914 GO:0003920 biolink:MolecularActivity GMP reductase activity Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH. KEGG_REACTION:R01134|EC:1.7.1.7|MetaCyc:GMP-REDUCT-RXN|RHEA:17185|Reactome:R-HSA-514604 go-plus.json guanylate reductase activity|NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity|NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)|NADPH:GMP oxidoreductase (deaminating) activity|inosine-5'-phosphate:NADP+ oxidoreductase (aminating)|guanosine 5'-monophosphate oxidoreductase activity|guanosine monophosphate reductase activity|guanosine 5'-monophosphate reductase activity|guanosine 5'-phosphate reductase activity http://purl.obolibrary.org/obo/GO_0003920 CHEBI:49214 biolink:ChemicalSubstance alpha-himachalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49214 chebi_ph7_3 GO:0003922 biolink:MolecularActivity GMP synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+). EC:6.3.5.2|RHEA:11680|Reactome:R-HSA-73792|MetaCyc:GMP-SYN-GLUT-RXN|Wikipedia:GMP_synthase_(glutamine-hydrolysing) go-plus.json guanylate synthetase (glutamine-hydrolyzing)|GMP synthetase (glutamine-hydrolyzing) activity|xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)|guanosine 5'-monophosphate synthetase activity|GMP synthetase (glutamine-hydrolysing)|glutamine amidotransferase activity|guanosine monophosphate synthetase (glutamine-hydrolyzing)|GMP synthase (glutamine-hydrolysing)|xanthosine 5'-phosphate amidotransferase activity http://purl.obolibrary.org/obo/GO_0003922 CHEBI:25268 biolink:ChemicalSubstance methyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25268 CHEBI:50202 biolink:ChemicalSubstance naringenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50202 chebi_ph7_3 GO:0003921 biolink:MolecularActivity GMP synthase activity Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+). RHEA:18301|MetaCyc:GMP-SYN-NH3-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0003921 CHEBI:50201 biolink:ChemicalSubstance (R)-naringenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50201 chebi_ph7_3 CHEBI:50208 biolink:ChemicalSubstance leachianone G go-plus.json http://purl.obolibrary.org/obo/CHEBI_50208 chebi_ph7_3 CHEBI:50207 biolink:ChemicalSubstance sophoraflavanone B go-plus.json http://purl.obolibrary.org/obo/CHEBI_50207 chebi_ph7_3 CHEBI:50205 biolink:ChemicalSubstance 3,4-dihydroxybenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_50205 chebi_ph7_3 CHEBI:50209 biolink:ChemicalSubstance sophoraflavanone G go-plus.json http://purl.obolibrary.org/obo/CHEBI_50209 chebi_ph7_3 CHEBI:49210 biolink:ChemicalSubstance beta-himachalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49210 chebi_ph7_3 CHEBI:25264 biolink:ChemicalSubstance methyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25264 CHEBI:25263 biolink:ChemicalSubstance methyl D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_25263 CHEBI:40886 biolink:ChemicalSubstance beta-L-arabinopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_40886 chebi_ph7_3 GO:0003928 biolink:MolecularActivity obsolete RAB small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json RAB small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0003928 GO:0003927 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003927 GO:0003929 biolink:MolecularActivity obsolete RAN small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json RAN small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0003929 GO:0003924 biolink:MolecularActivity GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate. Reactome:R-HSA-6814833|Reactome:R-HSA-5389842|Reactome:R-HSA-2584246|Reactome:R-HSA-8854173|Reactome:R-HSA-421835|Reactome:R-HSA-392133|Reactome:R-HSA-170666|Reactome:R-HSA-8854612|Reactome:R-HSA-164381|Reactome:R-HSA-203973|Reactome:R-HSA-2130725|Reactome:R-HSA-170686|Reactome:R-HSA-5623513|Reactome:R-HSA-177501|Reactome:R-HSA-380979|Reactome:R-HSA-1458485|Reactome:R-HSA-418574|RHEA:19669|Reactome:R-HSA-8868661|Reactome:R-HSA-5333615|Reactome:R-HSA-8854604|Reactome:R-HSA-8847534|Reactome:R-HSA-9645598|Reactome:R-HSA-8982025|Reactome:R-HSA-432707|Reactome:R-HSA-170685|Reactome:R-HSA-418582|Reactome:R-HSA-156923|Reactome:R-HSA-8849082|Reactome:R-HSA-5638006|Reactome:R-HSA-5658231|Reactome:R-HSA-983422|Reactome:R-HSA-5672017|Reactome:R-HSA-392212|Reactome:R-HSA-5694527|Reactome:R-HSA-5389839|Reactome:R-HSA-9640195|Reactome:R-HSA-8982021|Reactome:R-HSA-167415|Reactome:R-HSA-8854255|Reactome:R-HSA-165055|Reactome:R-HSA-6807877|Reactome:R-HSA-8854329|Reactome:R-HSA-555065|Reactome:R-HSA-1445143|Reactome:R-HSA-8847883|Reactome:R-HSA-9649736|Reactome:R-HSA-5665809|Reactome:R-HSA-8982020|Reactome:R-HSA-5419273|Reactome:R-HSA-8981353|Reactome:R-HSA-5419279|Reactome:R-HSA-428941|Reactome:R-HSA-2130641 go-plus.json ARF small monomeric GTPase activity|Rab small monomeric GTPase activity|RHEB small monomeric GTPase activity|dynamin GTPase activity|GTPase activity, coupled|heterotrimeric G-protein GTPase, gamma-subunit|signal-recognition-particle GTPase activity|protein-synthesizing GTPase activity, initiation|protein-synthesizing GTPase activity, termination|tubulin GTPase activity|Ras small monomeric GTPase activity|hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement|Sar small monomeric GTPase activity|protein-synthesizing GTPase activity, elongation|heterotrimeric G-protein GTPase, alpha-subunit|small monomeric GTPase activity|Ran small monomeric GTPase activity|heterotrimeric G-protein GTPase, beta-subunit|Rho small monomeric GTPase activity|heterotrimeric G-protein GTPase activity|protein-synthesizing GTPase activity http://purl.obolibrary.org/obo/GO_0003924 goslim_yeast|goslim_drosophila|goslim_generic|goslim_chembl GO:0003923 biolink:MolecularActivity GPI-anchor transamidase activity Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor. Reactome:R-HSA-162836 go-plus.json http://purl.obolibrary.org/obo/GO_0003923 GO:0003926 biolink:MolecularActivity obsolete ARF small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. go-plus.json ARF small monomeric GTPase activity http://purl.obolibrary.org/obo/GO_0003926 GO:0003925 biolink:MolecularActivity G protein activity A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP). EC:3.6.5.2|EC:3.6.5.1|MetaCyc:3.6.1.47-RXN|MetaCyc:3.6.1.46-RXN go-plus.json small monomeric G protein activity|signaling G protein activity|large G-protein GTPase activity|small monomeric GTPase activity|large G-protein activity|heterotrimeric G-protein GTPase activity http://purl.obolibrary.org/obo/GO_0003925 CHEBI:49204 biolink:ChemicalSubstance (+)-guaia-6,9-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49204 chebi_ph7_3 CHEBI:25236 biolink:ChemicalSubstance methoxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25236 CHEBI:25235 biolink:ChemicalSubstance monomethoxybenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_25235 CHEBI:49206 biolink:ChemicalSubstance (1xi,4xi,5xi)-guaia-6,9-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49206 chebi_ph7_3 CHEBI:49207 biolink:ChemicalSubstance (-)-guaia-6,9-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49207 chebi_ph7_3 CHEBI:25238 biolink:ChemicalSubstance methoxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25238 CHEBI:49209 biolink:ChemicalSubstance himachalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49209 CHEBI:49202 biolink:ChemicalSubstance elemental platinum go-plus.json http://purl.obolibrary.org/obo/CHEBI_49202 CHEBI:25230 biolink:ChemicalSubstance methionine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_25230 CHEBI:49201 biolink:ChemicalSubstance anti-ulcer drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_49201 CHEBI:64801 biolink:ChemicalSubstance (R)-tetraprenyl-beta-curcumene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64801 chebi_ph7_3 CHEBI:64800 biolink:ChemicalSubstance sativene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64800 chebi_ph7_3 CHEBI:64804 biolink:ChemicalSubstance sesquarterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64804 CHEBI:64802 biolink:ChemicalSubstance L-histidinal(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64802 chebi_ph7_3 CHEBI:39870 biolink:ChemicalSubstance propylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39870 CHEBI:8454 biolink:ChemicalSubstance progoitrin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_8454 chebi_ph7_3 CHEBI:64809 biolink:ChemicalSubstance tetrahydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64809 CHEBI:64808 biolink:ChemicalSubstance tetrahydro-4-hydroxyphenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64808 CHEBI:64807 biolink:ChemicalSubstance tetrahydrotyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64807 CHEBI:64806 biolink:ChemicalSubstance 2-demethylmenaquinol-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64806 chebi_ph7_3 CHEBI:25248 biolink:ChemicalSubstance methyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_25248 chebi_ph7_3 GO:0003900 biolink:MolecularActivity obsolete DNA-directed RNA polymerase I activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). go-plus.json DNA-directed RNA polymerase I activity http://purl.obolibrary.org/obo/GO_0003900 CHEBI:25240 biolink:ChemicalSubstance methoxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25240 CHEBI:25241 biolink:ChemicalSubstance methoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25241 CHEBI:64816 biolink:ChemicalSubstance doxorubicin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64816 chebi_ph7_3 GO:0003909 biolink:MolecularActivity DNA ligase activity Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+. Reactome:R-HSA-6782227|Reactome:R-HSA-5687675|Reactome:R-HSA-73931|Reactome:R-HSA-5651805|Reactome:R-HSA-5693604|Reactome:R-HSA-175258|Reactome:R-HSA-5690997|Reactome:R-HSA-5358592|Reactome:R-HSA-5649734|Reactome:R-HSA-69173|Reactome:R-HSA-174456|Reactome:R-HSA-5651789 go-plus.json http://purl.obolibrary.org/obo/GO_0003909 CHEBI:64815 biolink:ChemicalSubstance [(R)-2,2,3-trimethyl-2-oxocyclopent-3-en-1-yl]acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64815 chebi_ph7_3 CHEBI:64814 biolink:ChemicalSubstance 6-hydroxycamphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64814 chebi_ph7_3 GO:0003906 biolink:MolecularActivity DNA-(apurinic or apyrimidinic site) endonuclease activity Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). Reactome:R-HSA-5649711|Reactome:R-HSA-110375|Reactome:R-HSA-5649725 go-plus.json deoxyribonuclease (apurinic or apyrimidinic) activity|endonuclease VIII activity|apurinic/apyrimidinic endodeoxyribonuclease activity|UV endonuclease|apyrimidinic deoxyendoribonuclease activity|apurinic deoxyendoribonuclease activity|abasic deoxyendoribonuclease activity|AP deoxyendoribonuclease activity http://purl.obolibrary.org/obo/GO_0003906 GO:0003905 biolink:MolecularActivity alkylbase DNA N-glycosylase activity Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. EC:3.2.2.21|MetaCyc:3.2.2.21-RXN go-plus.json deoxyribonucleate 3-methyladenine glycosidase II|alkylbase DNA glycosidase activity|DNA-3-methyladenine glycosylase II|DNA glycosidase II activity|AlkA|3-methyladenine DNA glycosylase II|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA-3-methyladenine glycosidase II activity http://purl.obolibrary.org/obo/GO_0003905 CHEBI:64819 biolink:ChemicalSubstance [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_64819 GO:0003908 biolink:MolecularActivity methylated-DNA-[protein]-cysteine S-methyltransferase activity Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine. EC:2.1.1.63|Reactome:R-HSA-73892|RHEA:24000|MetaCyc:2.1.1.63-RXN go-plus.json DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity|methylated-DNA-protein-cysteine S-methyltransferase activity|6-O-methylguanine-DNA methyltransferase activity|O6-alkylguanine-DNA alkyltransferase|O-6-methylguanine-DNA-alkyltransferase activity|DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity|MGMT http://purl.obolibrary.org/obo/GO_0003908 GO:0003907 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003907 CHEBI:64817 biolink:ChemicalSubstance [(R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64817 GO:0003902 biolink:MolecularActivity obsolete DNA-directed RNA polymerase III activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). go-plus.json DNA-directed RNA polymerase III activity http://purl.obolibrary.org/obo/GO_0003902 GO:0003901 biolink:MolecularActivity obsolete DNA-directed RNA polymerase II activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). go-plus.json DNA-directed RNA polymerase II activity http://purl.obolibrary.org/obo/GO_0003901 GO:0003904 biolink:MolecularActivity deoxyribodipyrimidine photo-lyase activity Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light. RHEA:10672|MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN|EC:4.1.99.3 go-plus.json DNA-photoreactivating enzyme|photolyase activity|deoxyribonucleate pyrimidine dimer lyase (photosensitive)|DNA cyclobutane dipyrimidine photolyase activity|deoxyribocyclobutadipyrimidine pyrimidine-lyase activity|deoxyribonucleic photolyase activity|deoxyribodipyrimidine photolyase activity|phr A photolyase activity|deoxyribonucleic cyclobutane dipyrimidine photolyase activity|CPD photolyase activity|dipyrimidine photolyase (photosensitive)|photoreactivating enzyme activity|PRE|PhrB photolyase activity http://purl.obolibrary.org/obo/GO_0003904 GO:0052843 biolink:MolecularActivity inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+. MetaCyc:RXN-10977 go-plus.json http://purl.obolibrary.org/obo/GO_0052843 GO:0052842 biolink:MolecularActivity inositol diphosphate pentakisphosphate diphosphatase activity Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate. KEGG_REACTION:R05779|EC:3.6.1.52|RHEA:22384|Reactome:R-HSA-1855198|Reactome:R-HSA-2023971 go-plus.json http://purl.obolibrary.org/obo/GO_0052842 GO:0052841 biolink:MolecularActivity inositol bisdiphosphate tetrakisphosphate diphosphatase activity Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate. Reactome:R-HSA-2023973|Reactome:R-HSA-1855165 go-plus.json http://purl.obolibrary.org/obo/GO_0052841 GO:0052840 biolink:MolecularActivity inositol diphosphate tetrakisphosphate diphosphatase activity Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate. EC:3.6.1.52|MetaCyc:RXN-10963|Reactome:R-HSA-1855166 go-plus.json http://purl.obolibrary.org/obo/GO_0052840 GO:0052847 biolink:MolecularActivity inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+. MetaCyc:RXN-10975 go-plus.json http://purl.obolibrary.org/obo/GO_0052847 GO:0052846 biolink:MolecularActivity inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+. MetaCyc:RXN-10965 go-plus.json http://purl.obolibrary.org/obo/GO_0052846 GO:0052845 biolink:MolecularActivity inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+. MetaCyc:RXN-10964 go-plus.json http://purl.obolibrary.org/obo/GO_0052845 GO:0052844 biolink:MolecularActivity inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+. MetaCyc:RXN-10978 go-plus.json http://purl.obolibrary.org/obo/GO_0052844 GO:0052849 biolink:MolecularActivity NADPH-dependent curcumin reductase activity Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+. EC:1.3.1.n3|MetaCyc:RXN0-6676 go-plus.json http://purl.obolibrary.org/obo/GO_0052849 GO:0052848 biolink:MolecularActivity inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+. MetaCyc:RXN-10976 go-plus.json http://purl.obolibrary.org/obo/GO_0052848 CHEBI:132365 biolink:ChemicalSubstance EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_132365 CHEBI:132368 biolink:ChemicalSubstance glucuronate acceptor go-plus.json http://purl.obolibrary.org/obo/CHEBI_132368 chebi_ph7_3 CHEBI:132367 biolink:ChemicalSubstance beta-D-glucuronoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132367 chebi_ph7_3 CHEBI:74185 biolink:ChemicalSubstance N-tetracosenoyl-C17-sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74185 chebi_ph7_3 CHEBI:132362 biolink:ChemicalSubstance citrate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132362 CHEBI:132361 biolink:ChemicalSubstance O-(S-[2S,4S,6S]-2,4,6-trimethyl-very-long-chain fatty acyl-pantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132361 chebi_ph7_3 GO:0052854 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052854 GO:0052853 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052853 GO:0052852 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052852 GO:0052851 biolink:MolecularActivity ferric-chelate reductase (NADPH) activity Catalysis of the reaction: 2 Fe3+-siderophore + NADP(+) + H(+) -> 2 Fe2+-siderophore + NADPH. KEGG_REACTION:R09541|MetaCyc:RXN0-6555|EC:1.16.1.9|RHEA:28795 go-plus.json ferric reductase, NADPH-dependent activity|iron chelate reductase activity|ferric chelate reductase activity http://purl.obolibrary.org/obo/GO_0052851 GO:1904609 biolink:BiologicalProcess cellular response to monosodium L-glutamate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904609 GO:0052858 biolink:MolecularActivity peptidyl-lysine acetyltransferase activity Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine. go-plus.json peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor|acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity|peptidyl-lysine N6-acetyltransferase activity|acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity|peptidyl-lysine N(6)-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0052858 GO:1904608 biolink:BiologicalProcess response to monosodium L-glutamate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904608 GO:0052857 biolink:MolecularActivity NADPHX epimerase activity Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX. Reactome:R-HSA-6806966|EC:5.1.99.6|RHEA:32227 go-plus.json http://purl.obolibrary.org/obo/GO_0052857 GO:1904606 biolink:BiologicalProcess fat cell apoptotic process Any apoptotic process in a fat cell. go-plus.json adipocyte apoptotic process|adipose cell apoptotic process|adipocyte apoptosis|adipose cell apoptosis|fat cell apoptosis http://purl.obolibrary.org/obo/GO_1904606 GO:0052856 biolink:MolecularActivity NADHX epimerase activity Catalysis of the reaction: (R)-NADHX = (S)-NADHX. EC:5.1.99.6|RHEA:32215 go-plus.json http://purl.obolibrary.org/obo/GO_0052856 GO:1904605 biolink:BiologicalProcess positive regulation of advanced glycation end-product receptor activity Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity. go-plus.json up-regulation of advanced glycation end-product receptor activity|up-regulation of RAGE activity|activation of advanced glycation end-product receptor activity|up regulation of AGE receptor activity|positive regulation of AGE receptor activity|activation of AGE receptor activity|upregulation of RAGE activity|up regulation of advanced glycation end-product receptor activity|up-regulation of AGE receptor activity|up regulation of RAGE activity|positive regulation of RAGE activity|activation of RAGE activity|upregulation of advanced glycation end-product receptor activity|upregulation of AGE receptor activity http://purl.obolibrary.org/obo/GO_1904605 GO:0052855 biolink:MolecularActivity ADP-dependent NAD(P)H-hydrate dehydratase activity Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate. EC:4.2.1.136 go-plus.json reduced nicotinamide adenine dinucleotide hydrate dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing)|ADP-dependent H4NAD(P)OH dehydratase activity|ADP-dependent H(4)NAD(P)OH dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ADP-hydrolysing; NADH-forming) http://purl.obolibrary.org/obo/GO_0052855 GO:1904604 biolink:BiologicalProcess negative regulation of advanced glycation end-product receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity. go-plus.json downregulation of AGE receptor activity|inhibition of RAGE activity|down-regulation of advanced glycation end-product receptor activity|down-regulation of AGE receptor activity|negative regulation of AGE receptor activity|down regulation of RAGE activity|inhibition of AGE receptor activity|downregulation of RAGE activity|downregulation of advanced glycation end-product receptor activity|down regulation of advanced glycation end-product receptor activity|inhibition of advanced glycation end-product receptor activity|down-regulation of RAGE activity|negative regulation of RAGE activity|down regulation of AGE receptor activity http://purl.obolibrary.org/obo/GO_1904604 GO:1904603 biolink:BiologicalProcess regulation of advanced glycation end-product receptor activity Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity. go-plus.json regulation of RAGE activity|regulation of AGE receptor activity http://purl.obolibrary.org/obo/GO_1904603 GO:1904602 biolink:CellularComponent serotonin-activated cation-selective channel complex A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist. go-plus.json 5-HT-3 receptor complex|5-HT3 receptor complex|5HT3 receptor complex|serotonin receptor complex|5-hydroxytryptamine receptor 3 complex http://purl.obolibrary.org/obo/GO_1904602 GO:1904601 biolink:BiologicalProcess protein localization to actin fusion focus A process in which a protein is transported to, or maintained in, a location within an actin fusion focus. go-plus.json protein localisation in actin fusion focus|protein localization in actin fusion focus|protein localisation to actin fusion focus http://purl.obolibrary.org/obo/GO_1904601 GO:0052859 biolink:MolecularActivity glucan endo-1,4-beta-glucosidase activity Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans. EC:3.2.1.- go-plus.json beta-1,4-glucan hydrolase activity|beta-1,4-glucan 4-glucanohydrolase activity|endo-(1->4)-beta-D-glucanase activity|beta-1->4-glucan hydrolase activity|1,4-beta-D-glucan glucanohydrolase activity|endo-1,4-beta-D-glucanase activity|endo-(1,4)-beta-D-glucanase activity|endo-beta-1,4-glucanase activity|beta-1,4-glucanase activity|endo-1,4-beta-glucanase activity http://purl.obolibrary.org/obo/GO_0052859 GO:1904600 biolink:BiologicalProcess actin fusion focus assembly The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus. go-plus.json actin fusion focus formation http://purl.obolibrary.org/obo/GO_1904600 GO:0052850 biolink:MolecularActivity NADPH-dependent dihydrocurcumin reductase activity Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+. MetaCyc:RXN0-6677 go-plus.json dihydrocurcumin reductase (NADPH) activity http://purl.obolibrary.org/obo/GO_0052850 GO:0052865 biolink:BiologicalProcess 1-deoxy-D-xylulose 5-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. UniPathway:UPA00064 go-plus.json (2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate formation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthetic process|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthesis|1-deoxy-D-xylulose 5-phosphate biosynthesis|1-deoxy-D-xylulose 5-phosphate anabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate anabolism|1-deoxy-D-xylulose 5-phosphate synthesis|1-deoxy-D-xylulose 5-phosphate formation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate synthesis http://purl.obolibrary.org/obo/GO_0052865 GO:0003898 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003898 GO:0003897 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003897 GO:0052864 biolink:BiologicalProcess 1-deoxy-D-xylulose 5-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. go-plus.json 1-deoxy-D-xylulose 5-phosphate degradation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate degradation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolism|1-deoxy-D-xylulose 5-phosphate breakdown|1-deoxy-D-xylulose 5-phosphate catabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate breakdown|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolic process http://purl.obolibrary.org/obo/GO_0052864 GO:0052863 biolink:BiologicalProcess 1-deoxy-D-xylulose 5-phosphate metabolic process The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. go-plus.json (2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolic process|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolism|1-deoxy-D-xylulose 5-phosphate metabolism http://purl.obolibrary.org/obo/GO_0052863 GO:0052862 biolink:MolecularActivity glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3. MetaCyc:3.2.1.6-RXN|EC:3.2.1.6 go-plus.json 1,3-(1,4)-beta-D-glucan 4-glucanohydrolase activity|laminaranase activity|laminarinase activity http://purl.obolibrary.org/obo/GO_0052862 GO:0003899 biolink:MolecularActivity DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. Reactome:R-HSA-203901|Reactome:R-HSA-167113|Reactome:R-HSA-167117|Reactome:R-HSA-68913|Reactome:R-HSA-75873|Reactome:R-HSA-9697084|EC:2.7.7.6|Reactome:R-HSA-174425|Reactome:R-HSA-167121|Reactome:R-HSA-76576|Reactome:R-HSA-75869|Reactome:R-HSA-5601926|Reactome:R-HSA-6781824|Reactome:R-HSA-167115|Reactome:R-HSA-9670149|Reactome:R-HSA-74986|MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-427366|Reactome:R-HSA-167136|Reactome:R-HSA-75850|Reactome:R-HSA-9697085|Reactome:R-HSA-111264 go-plus.json DNA-directed RNA polymerase activity|C ribonucleic acid formation factors|C RNA formation factors|DNA-dependent RNA nucleotidyltransferase activity|RNA polymerase II activity|DNA-directed RNA polymerase II activity|DNA-dependent RNA polymerase activity|transcriptase|nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity|RNA polymerase I activity|RNA polymerase III activity|DNA-directed RNA polymerase III activity|DNA-directed RNA polymerase I activity|deoxyribonucleic acid-dependent ribonucleic acid polymerase activity|DNA-dependent ribonucleate nucleotidyltransferase activity|RNA nucleotidyltransferase (DNA-directed) activity http://purl.obolibrary.org/obo/GO_0003899 GO:0003894 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003894 GO:0052869 biolink:MolecularActivity arachidonic acid omega-hydroxylase activity Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid. KEGG_REACTION:R07041|EC:1.14.15.3 go-plus.json arachidonic acid hydroxylase activity|arachidonic acid:oxygen 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052869 GO:1904619 biolink:BiologicalProcess response to dimethyl sulfoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus. go-plus.json response to DMSO http://purl.obolibrary.org/obo/GO_1904619 GO:1904618 biolink:BiologicalProcess positive regulation of actin binding Any process that activates or increases the frequency, rate or extent of actin binding. go-plus.json upregulation of actin binding|upregulation of membrane associated actin binding|up regulation of actin binding|activation of actin binding|up regulation of membrane associated actin binding|positive regulation of membrane associated actin binding|up-regulation of actin binding|activation of membrane associated actin binding|up-regulation of membrane associated actin binding http://purl.obolibrary.org/obo/GO_1904618 GO:0052868 biolink:MolecularActivity protein-lysine lysyltransferase activity Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine. go-plus.json http://purl.obolibrary.org/obo/GO_0052868 GO:0003893 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003893 GO:1904617 biolink:BiologicalProcess negative regulation of actin binding Any process that stops, prevents or reduces the frequency, rate or extent of actin binding. go-plus.json down regulation of actin binding|inhibition of membrane associated actin binding|downregulation of actin binding|down regulation of membrane associated actin binding|downregulation of membrane associated actin binding|down-regulation of actin binding|inhibition of actin binding|down-regulation of membrane associated actin binding|negative regulation of membrane associated actin binding http://purl.obolibrary.org/obo/GO_1904617 GO:0052867 biolink:MolecularActivity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate. go-plus.json PtdIns(1,4,5)P3 phosphatase activity|triphosphoinositide phosphatase activity|PtdIns(1,4,5)P(3) phosphatase activity|phosphatidylinositol-trisphosphatase activity|phosphatidylinositol 1,4,5-trisphosphate phosphatase activity|phosphatidyl-myo-inositol-1,4,5-trisphosphate phosphatase activity|triphosphoinositide phosphomonoesterase activity http://purl.obolibrary.org/obo/GO_0052867 GO:0003896 biolink:MolecularActivity DNA primase activity Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases. EC:2.7.7.101 go-plus.json http://purl.obolibrary.org/obo/GO_0003896 GO:0003895 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003895 GO:1904616 biolink:BiologicalProcess regulation of actin binding Any process that modulates the frequency, rate or extent of actin binding. go-plus.json regulation of membrane associated actin binding http://purl.obolibrary.org/obo/GO_1904616 GO:0052866 biolink:MolecularActivity phosphatidylinositol phosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate. go-plus.json phosphoinositide phosphatase activity http://purl.obolibrary.org/obo/GO_0052866 GO:1904615 biolink:BiologicalProcess cellular response to biphenyl Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904615 GO:0003890 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003890 GO:1904614 biolink:BiologicalProcess response to biphenyl Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904614 GO:1904613 biolink:BiologicalProcess cellular response to 2,3,7,8-tetrachlorodibenzodioxine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus. go-plus.json cellular response to dioxin|cellular response to TCDD http://purl.obolibrary.org/obo/GO_1904613 GO:0003892 biolink:MolecularActivity obsolete proliferating cell nuclear antigen OBSOLETE. A nuclear protein that associates as a trimer and then interacts with delta DNA polymerase and epsilon DNA polymerase, acting as an auxiliary factor for DNA replication and DNA repair. go-plus.json proliferating cell nuclear antigen|PCNA http://purl.obolibrary.org/obo/GO_0003892 GO:1904612 biolink:BiologicalProcess response to 2,3,7,8-tetrachlorodibenzodioxine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus. go-plus.json response to dioxin|response to TCDD http://purl.obolibrary.org/obo/GO_1904612 GO:0003891 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003891 GO:1904611 biolink:BiologicalProcess cellular response to 3,3',4,4',5-pentachlorobiphenyl Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus. go-plus.json cellular response to PCB 126 http://purl.obolibrary.org/obo/GO_1904611 GO:1904610 biolink:BiologicalProcess response to 3,3',4,4',5-pentachlorobiphenyl Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus. go-plus.json response to PCB 126 http://purl.obolibrary.org/obo/GO_1904610 CHEBI:50191 biolink:ChemicalSubstance trideoxyhexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50191 CHEBI:50196 biolink:ChemicalSubstance dihydroxybenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_50196 CHEBI:50193 biolink:ChemicalSubstance quinone imine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50193 GO:0052861 biolink:MolecularActivity glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3. MetaCyc:3.2.1.6-RXN|EC:3.2.1.6 go-plus.json 1,3-(1,3)-beta-D-glucan 3-glucanohydrolase activity|laminaranase activity|laminarinase activity http://purl.obolibrary.org/obo/GO_0052861 GO:0052860 biolink:MolecularActivity 2'-deoxymugineic-acid 3-dioxygenase activity Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2. RHEA:20065|KEGG_REACTION:R07187|EC:1.14.11.25|MetaCyc:RXN-7983 go-plus.json 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0052860 CHEBI:156311 biolink:ChemicalSubstance trininoleoyl-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_156311 chebi_ph7_3 GO:0052876 biolink:MolecularActivity methylamine dehydrogenase (amicyanin) activity Catalysis of the reaction: 2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin]. KEGG_REACTION:R00606|RHEA:30207|UM-BBD_reactionID:r0075|EC:1.4.9.1 go-plus.json amine dehydrogenase|primary-amine dehydrogenase|MADH activity|methylamine:amicyanin oxidoreductase (deaminating) activity|methylamine dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052876 GO:0052875 biolink:MolecularActivity riboflavin reductase (NADH) activity Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+. MetaCyc:RXN-12445|RHEA:31455|EC:1.5.1.41|KEGG_REACTION:R09750 go-plus.json flavine mononucleotide reductase activity|NAD(P)H2:FMN oxidoreductase activity|riboflavin mononucleotide reductase activity|NAD(P)H:riboflavin oxidoreductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H-dependent FMN reductase activity|NAD(P)H-FMN reductase activity|riboflavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NAD(P)H2 dehydrogenase (FMN) activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide) reductase activity http://purl.obolibrary.org/obo/GO_0052875 GO:0052874 biolink:MolecularActivity FMN reductase (NADH) activity Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+. EC:1.5.1.39|KEGG_REACTION:R05705|RHEA:21620 go-plus.json NADH(2) dehydrogenase (FMN) activity|NADH2 dehydrogenase (FMN)|NADH dehydrogenase (FMN) activity|NADH2:FMN oxidoreductase activity|NADH-dependent FMN reductase activity|NADH-FMN reductase activity|NADH:FMN oxidoreductase activity|NADH:flavin oxidoreductase activity|FMNH2:NAD+ oxidoreductase activity|flavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NADH(2):FMN oxidoreductase activity|SsuE http://purl.obolibrary.org/obo/GO_0052874 GO:0052873 biolink:MolecularActivity FMN reductase (NADPH) activity Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+. EC:1.5.1.39|EC:1.5.1.38|KEGG_REACTION:R05706|RHEA:21624|Reactome:R-HSA-1222399 go-plus.json NADPH(2):FMN oxidoreductase activity|FMNH2:NADP+ oxidoreductase activity|NADPH(2) dehydrogenase (FMN) activity|flavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NADPH2 dehydrogenase (FMN)|NADPH dehydrogenase (FMN) activity|NADPH:FMN oxidoreductase activity|NADPH2:FMN oxidoreductase activity|SsuE|NADPH-dependent FMN reductase activity|NADPH-FMN reductase activity|NADPH:flavin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052873 GO:0052879 biolink:MolecularActivity 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate. KEGG_REACTION:R07062|EC:5.4.4.6|MetaCyc:1.13.11.44-RXN|RHEA:25399 go-plus.json (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming) activity|linoleate diol synthase activity|8-hydroperoxide isomerase activity http://purl.obolibrary.org/obo/GO_0052879 GO:1904629 biolink:BiologicalProcess response to diterpene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904629 GO:0052878 biolink:MolecularActivity linoleate 8R-lipoxygenase activity Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate. RHEA:25395|KEGG_REACTION:R07061|EC:1.13.11.60|MetaCyc:1.13.11.44-RXN go-plus.json 5,8-LDS (bifunctional enzyme) activity|7,8-LDS (bifunctional enzyme) activity|linoleate diol synthase activity|5,8-linoleate diol synthase (bifunctional enzyme) activity|7,8-linoleate diol synthase (bifunctional enzyme) activity http://purl.obolibrary.org/obo/GO_0052878 GO:1904628 biolink:BiologicalProcess cellular response to phorbol 13-acetate 12-myristate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus. go-plus.json cellular response to TPA|cellular response to response to PMA|cellular response to phorbol 12-tetradecanoate 13-acetate|cellular response to tetradecanoylphorbol acetate http://purl.obolibrary.org/obo/GO_1904628 GO:1904627 biolink:BiologicalProcess response to phorbol 13-acetate 12-myristate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus. go-plus.json response to phorbol 12-tetradecanoate 13-acetate|response to tetradecanoylphorbol acetate|response to TPA|response to PMA http://purl.obolibrary.org/obo/GO_1904627 GO:0052877 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor. EC:1.4.9.- go-plus.json http://purl.obolibrary.org/obo/GO_0052877 GO:1904626 biolink:BiologicalProcess positive regulation of glycine secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission. go-plus.json up regulation of glycine secretion, neurotransmission|upregulation of glycine secretion, neurotransmission|up-regulation of glycine secretion, neurotransmission|activation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_1904626 GO:1904625 biolink:BiologicalProcess negative regulation of glycine secretion, neurotransmission Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission. go-plus.json downregulation of glycine secretion, neurotransmission|down regulation of glycine secretion, neurotransmission|inhibition of glycine secretion, neurotransmission|down-regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_1904625 CHEBI:49195 biolink:ChemicalSubstance 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49195 chebi_ph7_3 GO:1904624 biolink:BiologicalProcess regulation of glycine secretion, neurotransmission Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission. go-plus.json http://purl.obolibrary.org/obo/GO_1904624 CHEBI:49198 biolink:ChemicalSubstance 2-O-sinapoyl-D-glucaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49198 GO:1904623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904623 CHEBI:49197 biolink:ChemicalSubstance 2-amino-2-deoxyisochorismic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49197 GO:1904622 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904622 GO:1904621 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904621 GO:1904620 biolink:BiologicalProcess cellular response to dimethyl sulfoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus. go-plus.json cellular response to DMSO http://purl.obolibrary.org/obo/GO_1904620 CHEBI:132356 biolink:ChemicalSubstance 4-O-({poly[(2R)-2-glucosyl-1-glycerylphosphonato]}-[2R]-1-glycerylphosphonato)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_132356 chebi_ph7_3 CHEBI:132358 biolink:ChemicalSubstance 1alpha-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_132358 chebi_ph7_3 CHEBI:50185 biolink:ChemicalSubstance fatty acid synthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50185 CHEBI:50183 biolink:ChemicalSubstance P450 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50183 GO:0052872 biolink:MolecularActivity tocotrienol omega-hydroxylase activity Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O . EC:1.14.13.- go-plus.json tocotrienol 13-hydroxylase activity http://purl.obolibrary.org/obo/GO_0052872 GO:0052871 biolink:MolecularActivity alpha-tocopherol omega-hydroxylase activity Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O . MetaCyc:RXN-11003 go-plus.json alpha-tocopherol 13-hydroxylase activity http://purl.obolibrary.org/obo/GO_0052871 CHEBI:50188 biolink:ChemicalSubstance provitamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50188 GO:0052870 biolink:MolecularActivity tocopherol omega-hydroxylase activity Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O . go-plus.json tocopherol 13-hydroxylase activity http://purl.obolibrary.org/obo/GO_0052870 GO:0003876 biolink:MolecularActivity AMP deaminase activity Catalysis of the reaction: AMP + H2O = IMP + NH3. Reactome:R-HSA-76590|MetaCyc:AMP-DEAMINASE-RXN|RHEA:14777|EC:3.5.4.6 go-plus.json adenosine monophosphate deaminase activity|5-adenylic acid deaminase activity|5-AMP deaminase activity|adenosine 5-monophosphate deaminase activity|adenylate deaminase activity|AMP aminohydrolase activity|adenylic deaminase activity|adenylate deaminase reaction|5-adenylate deaminase activity|adenylate desaminase activity|adenyl deaminase activity|adenosine 5-phosphate aminohydrolase activity|adenylic acid deaminase activity|myoadenylate deaminase activity|adenylate aminohydrolase activity|AMP aminase activity http://purl.obolibrary.org/obo/GO_0003876 GO:0052887 biolink:MolecularActivity 7,9,9'-tricis-neurosporene:quinone oxidoreductase activity Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol. KEGG_REACTION:R09658|EC:1.3.5.6|MetaCyc:RXN-11357 go-plus.json ZDS activity|9,9'-di-cis-zeta-carotene desaturase activity|zeta-carotene desaturase activity http://purl.obolibrary.org/obo/GO_0052887 GO:0003875 biolink:MolecularActivity ADP-ribosylarginine hydrolase activity Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose. MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN|EC:3.2.2.19|RHEA:20784 go-plus.json protein ADP-ribosylarginine hydrolase activity|omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADPribosylarginine hydrolase activity|protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADP-ribose-L-arginine cleaving enzyme activity|N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADP-ribose-L-arginine cleavage enzyme activity|nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity http://purl.obolibrary.org/obo/GO_0003875 GO:0052886 biolink:MolecularActivity 9,9'-dicis-carotene:quinone oxidoreductase activity Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol. EC:1.3.5.6|KEGG_REACTION:R09656|MetaCyc:RXN-11356|RHEA:30959 go-plus.json ZDS activity|9,9'-di-cis-zeta-carotene desaturase activity|zeta-carotene desaturase activity http://purl.obolibrary.org/obo/GO_0052886 GO:0003878 biolink:MolecularActivity ATP citrate synthase activity Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA. MetaCyc:PWY-5172|RHEA:21160|Reactome:R-HSA-75848|MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN|KEGG_REACTION:R00352|EC:2.3.3.8 go-plus.json citric cleavage enzyme activity|ATP-citric lyase activity|adenosine triphosphate citrate lyase activity|ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|ATP-citrate (pro-S)-lyase activity|ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|citrate cleavage enzyme activity|ATP citrate (pro-S)-lyase activity|ATP-citrate (pro-S-)-lyase activity|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|citrate-ATP lyase activity|acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating) http://purl.obolibrary.org/obo/GO_0003878 GO:0052885 biolink:MolecularActivity all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid. EC:3.1.1.64|RHEA:31771|KEGG_REACTION:R08388|MetaCyc:RXN-12550 go-plus.json retinoid isomerohydrolase activity|retinol isomerase activity|all-trans-retinylester 11-cis isomerohydrolase activity|all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity|all-trans-retinol isomerase:hydrolase activity http://purl.obolibrary.org/obo/GO_0052885 GO:0003877 biolink:MolecularActivity ATP adenylyltransferase activity Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate. EC:2.7.7.53|MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN|RHEA:16577 go-plus.json AP-4-A phosphorylase activity|adenine triphosphate adenylyltransferase activity|dinucleoside oligophosphate alphabeta-phosphorylase activity|diadenosinetetraphosphate alphabeta-phosphorylase activity|diadenosinetetraphosphate alpha-beta-phosphorylase activity|diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity|bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity|ADP:ATP adenylyltransferase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity|diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming) http://purl.obolibrary.org/obo/GO_0003877 GO:0052884 biolink:MolecularActivity all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate. EC:3.1.1.64|RHEA:31775|Reactome:R-HSA-2453833 go-plus.json retinoid isomerohydrolase activity|retinol isomerase activity|all-trans-retinyl-palmitate hydrolase activity|all-trans-retinol isomerase:hydrolase activity http://purl.obolibrary.org/obo/GO_0052884 GO:0003872 biolink:MolecularActivity 6-phosphofructokinase activity Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate. Reactome:R-HSA-70467|RHEA:16109|EC:2.7.1.11|MetaCyc:6PFRUCTPHOS-RXN go-plus.json fructose 6-phosphokinase activity|phosphofructokinase (phosphorylating)|6-phosphofructose 1-kinase activity|fructose 6-phosphate kinase activity|phosphohexokinase activity|PFK|phosphofructokinase I activity|phospho-1,6-fructokinase activity|D-fructose-6-phosphate 1-phosphotransferase activity|6-phosphofructokinase reduction|ATP-dependent phosphofructokinase activity|ATP:D-fructose-6-phosphate 1-phosphotransferase activity|nucleotide triphosphate-dependent phosphofructokinase activity http://purl.obolibrary.org/obo/GO_0003872 GO:0003871 biolink:MolecularActivity 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. EC:2.1.1.14|MetaCyc:HOMOCYSMET-RXN|KEGG_REACTION:R04405|RHEA:21196 go-plus.json methionine synthase (cobalamin-independent) activity|MetE|homocysteine methylase activity|methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity|cobalamin-independent methionine synthase activity|tetrahydropteroylglutamate-homocysteine transmethylase activity|tetrahydropteroyltriglutamate methyltransferase activity|methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity|5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity http://purl.obolibrary.org/obo/GO_0003871 GO:1904639 biolink:BiologicalProcess cellular response to resveratrol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904639 GO:0052889 biolink:BiologicalProcess 9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene. KEGG_REACTION:R07511|MetaCyc:RXN-12242 go-plus.json 7,9,7',9'-tetra-cis-lycopene biosynthesis from 9,9'-di-cis-zeta-carotene|9,9'-di-cis-zeta-carotene catabolism to 7,9,7',9'-tetra-cis-lycopene http://purl.obolibrary.org/obo/GO_0052889 GO:0003874 biolink:MolecularActivity 6-pyruvoyltetrahydropterin synthase activity Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate. MetaCyc:4.2.3.12-RXN|Reactome:R-HSA-1474184|EC:4.2.3.12|RHEA:22048|KEGG_REACTION:R04286 go-plus.json 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity|2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)|PTPS activity|6-pyruvoyl tetrahydrobiopterin synthase activity http://purl.obolibrary.org/obo/GO_0003874 GO:0052888 biolink:MolecularActivity obsolete dihydroorotate oxidase (fumarate) activity OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate. KEGG_REACTION:R01867|MetaCyc:RXN-9929|EC:1.3.98.1 go-plus.json dihydroorotate dehydrogenase activity|DHodehase activity|DHOD activity|DHOdase activity|dihydroorotate oxidase (fumarate) activity|dihydoorotic acid dehydrogenase activity|dihydroorotate oxidase activity http://purl.obolibrary.org/obo/GO_0052888 GO:1904638 biolink:BiologicalProcess response to resveratrol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904638 GO:0003873 biolink:MolecularActivity 6-phosphofructo-2-kinase activity Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+). MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN|Reactome:R-HSA-71802|KEGG_REACTION:R02732|EC:2.7.1.105|RHEA:15653 go-plus.json fructose 6-phosphate 2-kinase activity|6-phosphofructo-2-kinase (phosphorylating)|6-phosphofructose 2-kinase activity|ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity|ATP:D-fructose-6-phosphate 2-phosphotransferase activity|phosphofructokinase 2 activity http://purl.obolibrary.org/obo/GO_0003873 GO:1904637 biolink:BiologicalProcess cellular response to ionomycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904637 GO:1904636 biolink:BiologicalProcess response to ionomycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904636 CHEBI:49187 biolink:ChemicalSubstance (-)-abscisic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_49187 chebi_ph7_3 GO:0003870 biolink:MolecularActivity 5-aminolevulinate synthase activity Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA. EC:2.3.1.37|MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN|KEGG_REACTION:R00830|RHEA:12921|Reactome:R-HSA-189442 go-plus.json delta-aminolevulinate synthetase activity|5-aminolevulinic acid synthase activity|delta-ALA synthetase activity|5-aminolevulinate synthetase activity|aminolevulinic acid synthase activity|aminolevulinate synthetase activity|ALA synthetase activity|aminolevulinic synthetase activity|delta-aminolevulinic acid synthetase activity|delta-aminolevulinate synthase activity|5-aminolevulinic acid synthetase activity|ALAS activity|delta-aminolevulinic synthetase activity|alpha-aminolevulinic acid synthase activity|aminolevulinate synthase activity|aminolevulinic acid synthetase activity|ALA synthase activity|delta-aminolevulinic acid synthase activity|succinyl-CoA:glycine C-succinyltransferase (decarboxylating) http://purl.obolibrary.org/obo/GO_0003870 GO:1904635 biolink:BiologicalProcess positive regulation of glomerular visceral epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. go-plus.json activation of podocyte apoptotic process|up-regulation of podocyte apoptotic process|activation of podocyte apoptosis|positive regulation of glomerular visceral epithelial cell apoptosis|up-regulation of glomerular podocyte apoptotic process|up regulation of glomerular visceral epithelial cell apoptotic process|activation of glomerular visceral epithelial cell apoptotic process|positive regulation of podocyte apoptosis|upregulation of glomerular podocyte apoptosis|activation of glomerular visceral epithelial cell apoptosis|up regulation of podocyte apoptosis|up-regulation of glomerular visceral epithelial cell apoptosis|upregulation of glomerular podocyte apoptotic process|positive regulation of podocyte apoptotic process|up regulation of podocyte apoptotic process|up regulation of glomerular podocyte apoptosis|up-regulation of glomerular visceral epithelial cell apoptotic process|positive regulation of glomerular podocyte apoptosis|upregulation of podocyte apoptosis|upregulation of glomerular visceral epithelial cell apoptosis|up regulation of glomerular podocyte apoptotic process|activation of glomerular podocyte apoptosis|activation of glomerular podocyte apoptotic process|positive regulation of glomerular podocyte apoptotic process|upregulation of podocyte apoptotic process|upregulation of glomerular visceral epithelial cell apoptotic process|up-regulation of podocyte apoptosis|up-regulation of glomerular podocyte apoptosis|up regulation of glomerular visceral epithelial cell apoptosis http://purl.obolibrary.org/obo/GO_1904635 GO:1904634 biolink:BiologicalProcess negative regulation of glomerular visceral epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. go-plus.json downregulation of glomerular visceral epithelial cell apoptotic process|negative regulation of podocyte apoptosis|inhibition of glomerular podocyte apoptosis|down-regulation of podocyte apoptosis|inhibition of glomerular podocyte apoptotic process|negative regulation of glomerular visceral epithelial cell apoptosis|down-regulation of glomerular visceral epithelial cell apoptosis|negative regulation of podocyte apoptotic process|down-regulation of podocyte apoptotic process|down regulation of glomerular podocyte apoptosis|down-regulation of glomerular visceral epithelial cell apoptotic process|downregulation of podocyte apoptosis|downregulation of glomerular podocyte apoptosis|down regulation of glomerular podocyte apoptotic process|down regulation of podocyte apoptosis|downregulation of podocyte apoptotic process|inhibition of glomerular visceral epithelial cell apoptotic process|inhibition of glomerular visceral epithelial cell apoptosis|downregulation of glomerular podocyte apoptotic process|down regulation of podocyte apoptotic process|inhibition of podocyte apoptotic process|inhibition of podocyte apoptosis|down-regulation of glomerular podocyte apoptosis|negative regulation of glomerular podocyte apoptosis|down regulation of glomerular visceral epithelial cell apoptosis|down-regulation of glomerular podocyte apoptotic process|negative regulation of glomerular podocyte apoptotic process|downregulation of glomerular visceral epithelial cell apoptosis|down regulation of glomerular visceral epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_1904634 CHEBI:49189 biolink:ChemicalSubstance pristanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_49189 chebi_ph7_3 GO:1904633 biolink:BiologicalProcess regulation of glomerular visceral epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. go-plus.json regulation of glomerular podocyte apoptosis|regulation of podocyte apoptosis|regulation of glomerular podocyte apoptotic process|regulation of podocyte apoptotic process|regulation of glomerular visceral epithelial cell apoptosis http://purl.obolibrary.org/obo/GO_1904633 GO:1904632 biolink:BiologicalProcess cellular response to glucoside Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus. go-plus.json cellular response to glucosides http://purl.obolibrary.org/obo/GO_1904632 CHEBI:49188 biolink:ChemicalSubstance 2-methyl-branched fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_49188 chebi_ph7_3 GO:0062211 biolink:BiologicalProcess root regeneration The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root. go-plus.json http://purl.obolibrary.org/obo/GO_0062211 GO:1904631 biolink:BiologicalProcess response to glucoside Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus. go-plus.json response to glucosides http://purl.obolibrary.org/obo/GO_1904631 GO:0062210 biolink:BiologicalProcess shoot regeneration The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot. go-plus.json shoot system regeneration http://purl.obolibrary.org/obo/GO_0062210 GO:1904630 biolink:BiologicalProcess cellular response to diterpene Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904630 GO:0062213 biolink:MolecularActivity peroxynitrite isomerase activity Catalysis of the reaction: peroxynitrite = nitrate. RHEA:63116 go-plus.json http://purl.obolibrary.org/obo/GO_0062213 GO:1904640 biolink:BiologicalProcess response to methionine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904640 CHEBI:132320 biolink:ChemicalSubstance S-hexadecanoyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132320 GO:0062212 biolink:BiologicalProcess regulation of mitotic DNA replication initiation from early origin Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication. go-plus.json regulation of early replication origin firing http://purl.obolibrary.org/obo/GO_0062212 CHEBI:49190 biolink:ChemicalSubstance 2-methylpentadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_49190 chebi_ph7_3 CHEBI:132322 biolink:ChemicalSubstance S-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl)-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132322 CHEBI:132321 biolink:ChemicalSubstance S-choloyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132321 CHEBI:49192 biolink:ChemicalSubstance pimarane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49192 CHEBI:132324 biolink:ChemicalSubstance 20-HETrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_132324 CHEBI:50170 biolink:ChemicalSubstance 3-hydroxy-5alpha-pregnan-20-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50170 chebi_ph7_3 CHEBI:49191 biolink:ChemicalSubstance momilactone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_49191 chebi_ph7_3 CHEBI:132323 biolink:ChemicalSubstance 19-HETrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_132323 CHEBI:49194 biolink:ChemicalSubstance 3-(1-carboxyvinyloxy)anthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49194 CHEBI:49193 biolink:ChemicalSubstance diterpene lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_49193 CHEBI:132325 biolink:ChemicalSubstance 21-HDoHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_132325 CHEBI:50171 biolink:ChemicalSubstance 3-hydroxy-5beta-pregnan-20-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50171 chebi_ph7_3 GO:0052883 biolink:MolecularActivity tyrosine ammonia-lyase activity Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate. EC:4.3.1.23|RHEA:24906|EC:4.3.1.25 go-plus.json L-tyrosine ammonia-lyase activity|TAL activity|tyrase activity http://purl.obolibrary.org/obo/GO_0052883 GO:0003879 biolink:MolecularActivity ATP phosphoribosyltransferase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate. RHEA:18473|EC:2.4.2.17|MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN go-plus.json phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity|adenosine triphosphate phosphoribosyltransferase activity|phosphoribosyl ATP synthetase activity|1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity|phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity|phosphoribosyladenosine triphosphate pyrophosphorylase activity|phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity|phosphoribosyl-ATP pyrophosphorylase activity|phosphoribosyl-ATP diphosphorylase activity|phosphoribosyladenosine triphosphate synthetase activity http://purl.obolibrary.org/obo/GO_0003879 GO:0052882 biolink:MolecularActivity oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein. EC:1.20.9.- go-plus.json http://purl.obolibrary.org/obo/GO_0052882 CHEBI:50177 biolink:ChemicalSubstance dermatologic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_50177 GO:0052881 biolink:MolecularActivity 4-hydroxyphenylacetate 3-monooxygenase activity Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O. RHEA:30595|EC:1.14.14.9|MetaCyc:RXN-8505|UM-BBD_reactionID:r0301 go-plus.json 4 HPA 3-hydroxylase activity|p-hydroxyphenylacetate hydroxylase activity|p-hydroxyphenylacetate hydroxylase (FAD) activity|p-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetic acid-3-hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase (FAD) activity|4-hydroxyphenylacetate,FADH:oxygen oxidoreductase (3-hydroxylating) activity http://purl.obolibrary.org/obo/GO_0052881 CHEBI:50176 biolink:ChemicalSubstance keratolytic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_50176 GO:0052880 biolink:MolecularActivity oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein. EC:1.10.9.- go-plus.json http://purl.obolibrary.org/obo/GO_0052880 GO:0003887 biolink:MolecularActivity DNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group. Reactome:R-HSA-5656158|EC:2.7.7.7|Reactome:R-HSA-164513|Reactome:R-HSA-6782208|Reactome:R-HSA-73932|Reactome:R-HSA-5693593|Reactome:R-HSA-110317|Reactome:R-HSA-110368|Reactome:R-HSA-5649723|Reactome:R-HSA-69116|Reactome:R-HSA-68950|Reactome:R-HSA-164505|Reactome:R-HSA-174427|Reactome:R-HSA-110311|Reactome:R-HSA-110319|Reactome:R-HSA-5687640|Reactome:R-HSA-5656148|Reactome:R-HSA-5655892|Reactome:R-HSA-174444|Reactome:R-HSA-5655965|Reactome:R-HSA-5653840|Reactome:R-HSA-6786166|Reactome:R-HSA-5358579|Reactome:R-HSA-5691001|Reactome:R-HSA-111253|Reactome:R-HSA-5687360|Reactome:R-HSA-5649883|MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN go-plus.json DNA polymerase alpha|DNA nucleotidyltransferase (DNA-directed) activity|kappa DNA polymerase activity|epsilon DNA polymerase activity|Taq DNA polymerase|sequenase|DNA polymerase V activity|mu DNA polymerase activity|lambda DNA polymerase activity|nu DNA polymerase activity|sigma DNA polymerase activity|DNA replicase activity|DNA duplicase activity|DNA polymerase beta|DNA-dependent DNA polymerase activity|theta DNA polymerase activity|Klenow fragment|alpha DNA polymerase activity|deoxyribonucleic duplicase activity|Tca DNA polymerase|duplicase|Taq Pol I|zeta DNA polymerase activity|deoxyribonucleic acid duplicase activity|delta DNA polymerase activity|gamma DNA-directed DNA polymerase activity|DNA polymerase I|DNA polymerase III|DNA polymerase gamma|iota DNA polymerase activity|deoxyribonucleic polymerase I|DNA polymerase II|eta DNA polymerase activity|beta DNA polymerase activity|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity http://purl.obolibrary.org/obo/GO_0003887 GO:0052898 biolink:MolecularActivity N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2). EC:1.5.3.15|RHEA:25864 go-plus.json http://purl.obolibrary.org/obo/GO_0052898 GO:0003886 biolink:MolecularActivity DNA (cytosine-5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. RHEA:13681|MetaCyc:2.1.1.73-RXN|EC:2.1.1.37 go-plus.json DNA 5-cytosine methylase activity|deoxyribonucleic methylase activity|methylphosphotriester-DNA methyltransferase activity|S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity|DNA cytosine C5 methylase activity|DNA cytosine methylase activity|cytosine-specific DNA methyltransferase activity|deoxyribonucleic (cytosine-5-)-methyltransferase activity|DNA-cytosine methyltransferase activity|cytosine DNA methyltransferase activity|DNA cytosine C(5) methylase activity|deoxyribonucleic acid (cytosine-5-)-methyltransferase activity|cytosine 5-methyltransferase activity|cytosine DNA methylase activity|modification methylase activity|site-specific DNA-methyltransferase (cytosine-specific) activity|DNA-cytosine 5-methylase activity|type II DNA methylase activity|restriction-modification system activity http://purl.obolibrary.org/obo/GO_0003886 GO:0052897 biolink:MolecularActivity N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2). KEGG_REACTION:R09075|MetaCyc:RXN-10463|EC:1.5.3.15|RHEA:25972 go-plus.json N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity http://purl.obolibrary.org/obo/GO_0052897 GO:0052896 biolink:MolecularActivity spermidine oxidase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2). KEGG_REACTION:R01914|EC:1.5.3.14|RHEA:25820|MetaCyc:RXN-10747 go-plus.json spermidine:(acceptor) oxidoreductase activity|polyamine oxidase (propane-1,3-diamine-forming) activity http://purl.obolibrary.org/obo/GO_0052896 GO:0003889 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003889 CHEBI:50169 biolink:ChemicalSubstance brexanolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50169 chebi_ph7_3 GO:0052895 biolink:MolecularActivity N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide. MetaCyc:POLYAMINE-OXIDASE-RXN|EC:1.5.3.16 go-plus.json N1-acetylspermine oxidase activity http://purl.obolibrary.org/obo/GO_0052895 CHEBI:50168 biolink:ChemicalSubstance 3-hydroxypregnan-20-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_50168 chebi_ph7_3 GO:0003888 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003888 GO:0003883 biolink:MolecularActivity CTP synthase activity Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP. EC:6.3.4.2|RHEA:16597|MetaCyc:CTPSYN-RXN|Reactome:R-HSA-504054|Reactome:R-HSA-73647 go-plus.json UTP--ammonia ligase activity|UTP:ammonia ligase (ADP-forming)|CTP synthetase activity|uridine triphosphate aminase activity|cytidine 5'-triphosphate synthetase activity|cytidine triphosphate synthetase activity http://purl.obolibrary.org/obo/GO_0003883 GO:0003882 biolink:MolecularActivity CDP-diacylglycerol-serine O-phosphatidyltransferase activity Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine. RHEA:16913|MetaCyc:PHOSPHASERSYN-RXN|EC:2.7.8.8 go-plus.json CDPdiacylglycerol-serine O-phosphatidyltransferase activity|CDP-diglycerine-serine O-phosphatidyltransferase activity|CDP-diglyceride:serine phosphatidyltransferase activity|phosphatidylserine synthase activity|CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|CDPdiglyceride-serine O-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|phosphatidylserine synthetase activity|PS synthase activity|CDP-diglyceride-L-serine phosphatidyltransferase activity|serine exchange enzyme http://purl.obolibrary.org/obo/GO_0003882 GO:0003885 biolink:MolecularActivity D-arabinono-1,4-lactone oxidase activity Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+). RHEA:23756|MetaCyc:1.1.3.37-RXN|EC:1.1.3.37|KEGG_REACTION:R02715 go-plus.json D-arabinono-1,4-lactone:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0003885 GO:0003884 biolink:MolecularActivity D-amino-acid oxidase activity Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide. Reactome:R-HSA-389821|EC:1.4.3.3|MetaCyc:D-AMINO-ACID-OXIDASE-RXN|RHEA:21816 go-plus.json D-amino-acid:oxygen oxidoreductase (deaminating)|L-amino acid:O2 oxidoreductase activity|new yellow enzyme http://purl.obolibrary.org/obo/GO_0003884 GO:1904649 biolink:BiologicalProcess regulation of fat cell apoptotic process Any process that modulates the frequency, rate or extent of fat cell apoptotic process. go-plus.json regulation of adipose cell apoptosis|regulation of fat cell apoptosis|regulation of adipocyte apoptosis|regulation of adipose cell apoptotic process|regulation of adipocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904649 GO:0052899 biolink:MolecularActivity N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine. MetaCyc:RXN-10460|RHEA:25868|EC:1.5.3.13 go-plus.json N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity http://purl.obolibrary.org/obo/GO_0052899 CHEBI:49174 biolink:ChemicalSubstance 2-hydroxy-3-methylhexadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_49174 GO:1904648 biolink:BiologicalProcess cellular response to rotenone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904648 CHEBI:49173 biolink:ChemicalSubstance 2-hydroxy-3-methylacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_49173 GO:1904647 biolink:BiologicalProcess response to rotenone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904647 GO:0003881 biolink:MolecularActivity CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+). Reactome:R-HSA-1482976|RHEA:11580|EC:2.7.8.11|MetaCyc:2.7.8.11-RXN|KEGG_REACTION:R01802 go-plus.json cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity|CDP-diglyceride:inositol transferase activity|CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity|CDP-DG:inositol transferase activity|cytidine diphosphoglyceride-inositol transferase activity|CDP-diacylglycerol--inositol phosphatidyltransferase activity|CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity|phosphatidylinositol synthase activity|CDP diglyceride-inositol phosphatidyltransferase activity|CDP-diglyceride-inositol transferase activity|CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity|cytidine diphosphoglyceride-inositol phosphatidyltransferase activity|cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity http://purl.obolibrary.org/obo/GO_0003881 GO:1904646 biolink:BiologicalProcess cellular response to amyloid-beta Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus. go-plus.json cellular response to beta-amyloids|cellular response to beta-amyloid http://purl.obolibrary.org/obo/GO_1904646 CHEBI:49175 biolink:ChemicalSubstance 2-hydroxy-3-methylhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49175 GO:1904645 biolink:BiologicalProcess response to amyloid-beta Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus. go-plus.json response to beta-amyloids|response to beta-amyloid http://purl.obolibrary.org/obo/GO_1904645 GO:0003880 biolink:MolecularActivity protein C-terminal carboxyl O-methyltransferase activity Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein. go-plus.json C-terminal protein carboxyl methyltransferase activity http://purl.obolibrary.org/obo/GO_0003880 GO:1904644 biolink:BiologicalProcess cellular response to curcumin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904644 CHEBI:49178 biolink:ChemicalSubstance 2,3-dihydroxy-2,3-dihydrobenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_49178 GO:1904643 biolink:BiologicalProcess response to curcumin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904643 CHEBI:49177 biolink:ChemicalSubstance (6R)-dehydrovomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49177 chebi_ph7_3 GO:0062200 biolink:BiologicalProcess RAM/MOR signaling pathway An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase. go-plus.json MOR signaling pathway|RAM signaling pathway|morphogenesis Orb6 network http://purl.obolibrary.org/obo/GO_0062200 GO:1904642 biolink:BiologicalProcess cellular response to dinitrophenol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus. go-plus.json cellular response to dinitrophenols http://purl.obolibrary.org/obo/GO_1904642 GO:1904641 biolink:BiologicalProcess response to dinitrophenol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus. go-plus.json response to dinitrophenols http://purl.obolibrary.org/obo/GO_1904641 CHEBI:49179 biolink:ChemicalSubstance cis-3,4-didehydroadipoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_49179 GO:1904651 biolink:BiologicalProcess positive regulation of fat cell apoptotic process Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process. go-plus.json up-regulation of adipose cell apoptotic process|activation of adipose cell apoptotic process|activation of adipose cell apoptosis|up-regulation of fat cell apoptotic process|activation of fat cell apoptosis|activation of fat cell apoptotic process|up-regulation of adipocyte apoptosis|positive regulation of adipose cell apoptosis|positive regulation of fat cell apoptosis|up regulation of adipose cell apoptosis|up-regulation of adipocyte apoptotic process|up regulation of fat cell apoptosis|positive regulation of adipose cell apoptotic process|up regulation of adipose cell apoptotic process|upregulation of adipocyte apoptosis|up regulation of fat cell apoptotic process|upregulation of adipose cell apoptosis|upregulation of adipocyte apoptotic process|upregulation of fat cell apoptosis|up regulation of adipocyte apoptosis|upregulation of adipose cell apoptotic process|upregulation of fat cell apoptotic process|positive regulation of adipocyte apoptosis|up-regulation of adipose cell apoptosis|up regulation of adipocyte apoptotic process|up-regulation of fat cell apoptosis|positive regulation of adipocyte apoptotic process|activation of adipocyte apoptotic process|activation of adipocyte apoptosis http://purl.obolibrary.org/obo/GO_1904651 GO:0062202 biolink:MolecularActivity Labd-13(16),14-diene-9-ol synthase activity Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol. RHEA:62184 go-plus.json http://purl.obolibrary.org/obo/GO_0062202 GO:1904650 biolink:BiologicalProcess negative regulation of fat cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process. go-plus.json down-regulation of adipose cell apoptosis|negative regulation of adipose cell apoptosis|down-regulation of adipocyte apoptotic process|negative regulation of adipocyte apoptotic process|down-regulation of fat cell apoptosis|negative regulation of fat cell apoptosis|down-regulation of adipose cell apoptotic process|negative regulation of adipose cell apoptotic process|inhibition of adipocyte apoptotic process|inhibition of adipocyte apoptosis|down-regulation of fat cell apoptotic process|downregulation of adipose cell apoptosis|downregulation of fat cell apoptosis|down regulation of adipose cell apoptosis|down regulation of adipocyte apoptosis|down regulation of fat cell apoptosis|downregulation of adipose cell apoptotic process|downregulation of fat cell apoptotic process|downregulation of adipocyte apoptosis|down regulation of adipose cell apoptotic process|down regulation of adipocyte apoptotic process|inhibition of adipose cell apoptotic process|inhibition of adipose cell apoptosis|down regulation of fat cell apoptotic process|inhibition of fat cell apoptosis|inhibition of fat cell apoptotic process|downregulation of adipocyte apoptotic process|down-regulation of adipocyte apoptosis|negative regulation of adipocyte apoptosis http://purl.obolibrary.org/obo/GO_1904650 GO:0062201 biolink:CellularComponent actin wave A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0062201 GO:0062204 biolink:MolecularActivity (13S)-vitexifolin A synthase activity Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate. RHEA:40027 go-plus.json http://purl.obolibrary.org/obo/GO_0062204 GO:0062203 biolink:MolecularActivity Viteagnusin D synthase activity Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D. RHEA:62180 go-plus.json http://purl.obolibrary.org/obo/GO_0062203 GO:0062206 biolink:MolecularActivity manoyl oxide synthase activity Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate. EC:4.2.3.190|RHEA:54516 go-plus.json http://purl.obolibrary.org/obo/GO_0062206 CHEBI:49181 biolink:ChemicalSubstance (R)-1,2-didecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49181 chebi_ph7_3 GO:0062205 biolink:MolecularActivity miltiradiene synthase activity Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene. EC:4.2.3.131|MetaCyc:RXN-13338|RHEA:33983 go-plus.json multiradiene synthase activity http://purl.obolibrary.org/obo/GO_0062205 CHEBI:49180 biolink:ChemicalSubstance cis-3,4-didehydroadipoyl-CoA semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_49180 GO:0062208 biolink:BiologicalProcess positive regulation of pattern recognition receptor signaling pathway Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0062208 CHEBI:49183 biolink:ChemicalSubstance phosphatidylcholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49183 GO:0062207 biolink:BiologicalProcess regulation of pattern recognition receptor signaling pathway Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0062207 CHEBI:49182 biolink:ChemicalSubstance 1,5-anhydro-D-mannitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49182 chebi_ph7_3 GO:0052890 biolink:MolecularActivity oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin. EC:1.3.8.- go-plus.json http://purl.obolibrary.org/obo/GO_0052890 CHEBI:50163 biolink:ChemicalSubstance alpha-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50163 GO:0062209 biolink:BiologicalProcess spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination. go-plus.json crossover interference|regulation of spatial distribution of meiotic DSB formation involved in reciprocal meiotic recombination|regulation of spatial distribution of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|DSB interference http://purl.obolibrary.org/obo/GO_0062209 CHEBI:50160 biolink:ChemicalSubstance steroid acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_50160 GO:0052894 biolink:MolecularActivity norspermine:oxygen oxidoreductase activity Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide. MetaCyc:RXN-10464|EC:1.5.3.16 go-plus.json norspermine oxidase activity http://purl.obolibrary.org/obo/GO_0052894 GO:0052893 biolink:MolecularActivity N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide. MetaCyc:RXN-10465|EC:1.5.3.14|RHEA:25996 go-plus.json polyamine oxidase (propane-1,3-diamine-forming) activity http://purl.obolibrary.org/obo/GO_0052893 CHEBI:50166 biolink:ChemicalSubstance D-gamma-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50166 GO:0052892 biolink:MolecularActivity aromatic (S)-hydroxynitrile lyase activity Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide. EC:4.1.2.47|RHEA:54660|KEGG_REACTION:R09359|MetaCyc:RXN-11732 go-plus.json oxynitrilase activity|(S)-hydroxynitrile lyase activity|(S)-selective hydroxynitrile lyase activity|(S)-oxynitrilase activity|hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity http://purl.obolibrary.org/obo/GO_0052892 GO:0052891 biolink:MolecularActivity aliphatic (S)-hydroxynitrile lyase activity Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide. EC:4.1.2.47|MetaCyc:RXN-11731 go-plus.json oxynitrilase activity|(S)-hydroxynitrile lyase activity|(S)-selective hydroxynitrile lyase activity|(S)-oxynitrilase activity|hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity http://purl.obolibrary.org/obo/GO_0052891 CHEBI:50164 biolink:ChemicalSubstance gamma-glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50164 GO:0003854 biolink:MolecularActivity 3-beta-hydroxy-delta5-steroid dehydrogenase activity Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+). RHEA:24076|MetaCyc:1.1.1.145-RXN|Reactome:R-HSA-196350|EC:1.1.1.145|Reactome:R-HSA-193789|Reactome:R-HSA-196372|Reactome:R-HSA-192097|Reactome:R-HSA-193816 go-plus.json 3beta-HSDH|5-ene-3-beta-hydroxysteroid dehydrogenase activity|delta5-3beta-hydroxysteroid dehydrogenase activity|steroid-delta5-3beta-ol dehydrogenase activity|3beta-hydroxy-5-ene-steroid dehydrogenase activity|3-beta-hydroxy-D5-steroid dehydrogenase activity|3beta-hydroxy-delta5-steroid dehydrogenase activity|3beta-hydroxy steroid dehydrogenase/isomerase activity|3beta-hydroxy-5-ene-steroid oxidoreductase activity|3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity|3beta-hydroxy-5-ene steroid dehydrogenase activity|3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|progesterone reductase activity|3-beta-hydroxy-5-ene steroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003854 GO:0003853 biolink:MolecularActivity 2-methylacyl-CoA dehydrogenase activity Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor. RHEA:13261|EC:1.3.99.12|MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN go-plus.json branched-chain acyl-CoA dehydrogenase activity|2-methylbutanoyl-CoA:acceptor oxidoreductase activity|2-methyl branched chain acyl-CoA dehydrogenase activity|2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity http://purl.obolibrary.org/obo/GO_0003853 GO:0003856 biolink:MolecularActivity 3-dehydroquinate synthase activity Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate. EC:4.2.3.4|KEGG_REACTION:R03083|MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN|RHEA:21968 go-plus.json http://purl.obolibrary.org/obo/GO_0003856 GO:0003855 biolink:MolecularActivity 3-dehydroquinate dehydratase activity Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O. RHEA:21096|KEGG_REACTION:R03084|MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN|EC:4.2.1.10 go-plus.json DHQase|3-dehydroquinate hydrolase activity|5-dehydroquinate dehydratase activity|5-dehydroquinase activity|3-dehydroquinase activity|dehydroquinate dehydratase activity|5-dehydroquinate hydro-lyase activity|dehydroquinase activity|3-dehydroquinate hydro-lyase activity|3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming) http://purl.obolibrary.org/obo/GO_0003855 CHEBI:50157 biolink:ChemicalSubstance (5-hydroxyindol-3-yl)acetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_50157 chebi_ph7_3 GO:0003850 biolink:MolecularActivity 2-deoxyglucose-6-phosphatase activity Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate. MetaCyc:3.1.3.68-RXN|EC:3.1.3.68|RHEA:22236|KEGG_REACTION:R02587 go-plus.json 2-deoxy-D-glucose-6-phosphate phosphohydrolase activity|2-deoxyglucose-6-phosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0003850 GO:0003852 biolink:MolecularActivity 2-isopropylmalate synthase activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+). MetaCyc:2-ISOPROPYLMALATESYN-RXN|RHEA:21524|EC:2.3.3.13|KEGG_REACTION:R01213 go-plus.json 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity|alpha-isopropylmalate synthase activity|alpha-IPM synthetase activity|isopropylmalate synthetase activity|acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|isopropylmalate synthase activity|alpha-isopropylmalate synthetase activity|alpha-isopropylmalic synthetase activity http://purl.obolibrary.org/obo/GO_0003852 GO:0003851 biolink:MolecularActivity 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine. MetaCyc:2.4.1.45-RXN|EC:2.4.1.47|RHEA:10856 go-plus.json UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity|cerebroside synthase activity|UDP-galactose-ceramide galactosyltransferase activity|UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity|UDPgalactose:ceramide galactosyltransferase activity|UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0003851 GO:1904659 biolink:BiologicalProcess glucose transmembrane transport The process in which glucose is transported across a membrane. go-plus.json glucose transport http://purl.obolibrary.org/obo/GO_1904659 CHEBI:25196 biolink:ChemicalSubstance mercury molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_25196 CHEBI:132306 biolink:ChemicalSubstance (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132306 GO:1904658 biolink:BiologicalProcess positive regulation of sensory perception of sweet taste Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste. go-plus.json up-regulation of sweet taste perception|activation of sweet taste perception|up regulation of sensory perception of sweet taste|activation of sensory perception of sweet taste|positive regulation of sweet taste perception|up regulation of sweet taste perception|up-regulation of sensory perception of sweet taste|upregulation of sweet taste perception|upregulation of sensory perception of sweet taste http://purl.obolibrary.org/obo/GO_1904658 CHEBI:25195 biolink:ChemicalSubstance mercury atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_25195 chebi_ph7_3 GO:1904657 biolink:BiologicalProcess negative regulation of sensory perception of sweet taste Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste. go-plus.json downregulation of sensory perception of sweet taste|negative regulation of sweet taste perception|down-regulation of sweet taste perception|down-regulation of sensory perception of sweet taste|inhibition of sensory perception of sweet taste|downregulation of sweet taste perception|down regulation of sweet taste perception|inhibition of sweet taste perception|down regulation of sensory perception of sweet taste http://purl.obolibrary.org/obo/GO_1904657 GO:1904656 biolink:BiologicalProcess regulation of sensory perception of sweet taste Any process that modulates the frequency, rate or extent of sensory perception of sweet taste. go-plus.json regulation of sweet taste perception http://purl.obolibrary.org/obo/GO_1904656 CHEBI:49164 biolink:ChemicalSubstance (6S,9R)-vomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49164 chebi_ph7_3 GO:0062231 biolink:BiologicalProcess positive regulation of larval somatic muscle development Any process that increases the rate, frequency or extent of larval somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062231 GO:1904655 biolink:BiologicalProcess positive regulation of lung alveolus development Any process that activates or increases the frequency, rate or extent of lung alveolus development. go-plus.json up regulation of alveolarization|positive regulation of alveolarization|activation of alveolarization|upregulation of lung alveolus development|upregulation of alveologenesis|up-regulation of alveolarization|up regulation of lung alveolus development|up-regulation of alveologenesis|activation of alveologenesis|activation of lung alveolus development|upregulation of alveolarization|positive regulation of alveologenesis|up-regulation of lung alveolus development|up regulation of alveologenesis http://purl.obolibrary.org/obo/GO_1904655 CHEBI:49167 biolink:ChemicalSubstance anti-asthmatic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_49167 GO:0062230 biolink:BiologicalProcess negative regulation of larval somatic muscle development Any process that decreases the rate, frequency or extent of larval somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062230 GO:1904654 biolink:BiologicalProcess negative regulation of lung alveolus development Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development. go-plus.json downregulation of alveologenesis|down regulation of alveologenesis|inhibition of alveologenesis|negative regulation of alveolarization|down-regulation of alveolarization|down regulation of lung alveolus development|downregulation of lung alveolus development|inhibition of alveolarization|down-regulation of lung alveolus development|negative regulation of alveologenesis|down-regulation of alveologenesis|down regulation of alveolarization|inhibition of lung alveolus development|downregulation of alveolarization http://purl.obolibrary.org/obo/GO_1904654 CHEBI:132309 biolink:ChemicalSubstance S-butyryl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132309 CHEBI:49169 biolink:ChemicalSubstance D-dopa go-plus.json http://purl.obolibrary.org/obo/CHEBI_49169 GO:1904653 biolink:BiologicalProcess regulation of lung alveolus development Any process that modulates the frequency, rate or extent of lung alveolus development. go-plus.json regulation of alveologenesis|regulation of alveolarization http://purl.obolibrary.org/obo/GO_1904653 GO:0062233 biolink:BiologicalProcess F2-isoprostane catabolic process The chemical reactions and pathways resulting in the breakdown of F2-isoprostane. go-plus.json http://purl.obolibrary.org/obo/GO_0062233 GO:0062232 biolink:BiologicalProcess prostanoid catabolic process The chemical reactions and pathways resulting in the breakdown of prostanoids. go-plus.json http://purl.obolibrary.org/obo/GO_0062232 GO:1904652 biolink:BiologicalProcess protein localization to cell division site involved in cell separation after cytokinesis Any protein localization to cell division site that is involved in cell separation after cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904652 CHEBI:49168 biolink:ChemicalSubstance dopa go-plus.json http://purl.obolibrary.org/obo/CHEBI_49168 CHEBI:25197 biolink:ChemicalSubstance mercury cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25197 GO:1904662 biolink:BiologicalProcess positive regulation of sensory perception of bitter taste Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste. go-plus.json up regulation of sensory perception of bitter taste|upregulation of bitter taste perception|upregulation of sensory perception of bitter taste|up regulation of bitter taste perception|activation of bitter taste perception|positive regulation of bitter taste perception|activation of sensory perception of bitter taste|up-regulation of sensory perception of bitter taste|up-regulation of bitter taste perception http://purl.obolibrary.org/obo/GO_1904662 GO:0062235 biolink:BiologicalProcess axonemal basal plate assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate. go-plus.json axoneme basal plate assembly|basal plate assembly|axonemal basal plate formation http://purl.obolibrary.org/obo/GO_0062235 GO:0062234 biolink:BiologicalProcess platelet activating factor catabolic process The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine. go-plus.json PAF catabolic process|2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine catabolic process http://purl.obolibrary.org/obo/GO_0062234 GO:1904661 biolink:BiologicalProcess negative regulation of sensory perception of bitter taste Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste. go-plus.json downregulation of sensory perception of bitter taste|down regulation of sensory perception of bitter taste|down regulation of bitter taste perception|inhibition of sensory perception of bitter taste|downregulation of bitter taste perception|down-regulation of bitter taste perception|negative regulation of bitter taste perception|down-regulation of sensory perception of bitter taste|inhibition of bitter taste perception http://purl.obolibrary.org/obo/GO_1904661 GO:0062237 biolink:BiologicalProcess protein localization to postsynapse Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell. go-plus.json http://purl.obolibrary.org/obo/GO_0062237 GO:1904660 biolink:BiologicalProcess regulation of sensory perception of bitter taste Any process that modulates the frequency, rate or extent of sensory perception of bitter taste. go-plus.json regulation of bitter taste perception http://purl.obolibrary.org/obo/GO_1904660 GO:0062236 biolink:BiologicalProcess ionocyte differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0062236 GO:0062239 biolink:MolecularActivity heterochromatin-nuclear membrane anchor activity Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization. go-plus.json heterochromatin-nuclear membrane tether activity|nuclear membrane-heterochromatin tether activity|nuclear membrane-heterochromatin anchor activity http://purl.obolibrary.org/obo/GO_0062239 CHEBI:132302 biolink:ChemicalSubstance (8S,9R)-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_132302 GO:0062238 biolink:CellularComponent Smp focus A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I. go-plus.json Smp dot http://purl.obolibrary.org/obo/GO_0062238 CHEBI:49172 biolink:ChemicalSubstance 1,2-diglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_49172 chebi_ph7_3 CHEBI:132303 biolink:ChemicalSubstance (8R,9S)-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_132303 GO:0003858 biolink:MolecularActivity 3-hydroxybutyrate dehydrogenase activity Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH. KEGG_REACTION:R01361|Reactome:R-HSA-73912|Reactome:R-HSA-5696457|MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|Reactome:R-HSA-73920|EC:1.1.1.30|RHEA:20521 go-plus.json D-beta-hydroxybutyrate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003858 GO:0003857 biolink:MolecularActivity 3-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+). Reactome:R-HSA-77342|Reactome:R-HSA-77254|Reactome:R-HSA-193455|Reactome:R-HSA-389995|UM-BBD_enzymeID:e0664|Reactome:R-HSA-70837|MetaCyc:OHACYL-COA-DEHYDROG-RXN|Reactome:R-HSA-6809264|Reactome:R-HSA-77323|Reactome:R-HSA-508369|EC:1.1.1.35|Reactome:R-HSA-390251|Reactome:R-HSA-193508|Reactome:R-HSA-77312|Reactome:R-HSA-77303|RHEA:22432|Reactome:R-HSA-77331|Reactome:R-HSA-77283 go-plus.json 3-oxoacyl-thioester reductase activity|beta-keto-reductase activity|beta-ketoacyl-CoA reductase|beta-hydroxyacylcoenzyme A dehydrogenase activity|beta-hydroxybutyrylcoenzyme A dehydrogenase activity|L-3-hydroxyacyl CoA dehydrogenase activity|L-3-hydroxyacyl coenzyme A dehydrogenase activity|beta-hydroxyacyl-coenzyme A synthetase activity|beta-hydroxyacyl dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003857 GO:0003859 biolink:MolecularActivity 3-hydroxybutyryl-CoA dehydratase activity Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O. EC:4.2.1.55|MetaCyc:3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN|RHEA:17849|KEGG_REACTION:R03027 go-plus.json D-3-hydroxybutyryl-CoA dehydratase activity|D-3-hydroxybutyryl coenzyme A dehydratase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)|enoyl coenzyme A hydrase (D)|crotonase activity http://purl.obolibrary.org/obo/GO_0003859 GO:0003865 biolink:MolecularActivity 3-oxo-5-alpha-steroid 4-dehydrogenase activity Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor. Reactome:R-HSA-9705713|Reactome:R-HSA-9705714|MetaCyc:1.3.99.5-RXN|Reactome:R-HSA-469659|EC:1.3.99.5 go-plus.json 4-ene-3-ketosteroid-5alpha-oxidoreductase activity|delta4-3-oxosteroid-5alpha-reductase|3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity|3-oxo-5alpha-steroid 4-dehydrogenase activity|delta4-3-oxo steroid reductase activity|testosterone 5alpha-reductase|steroid 5alpha-reductase|steroid 5-alpha-reductase activity|5alpha-reductase|delta4-3-ketosteroid5alpha-oxidoreductase activity|3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity|delta4-3-keto steroid 5alpha-reductase activity|3-keto-delta4-steroid-5alpha-reductase activity|delta4-5alpha-dehydrogenase activity|3-oxosteroid delta4-dehydrogenase|steroid delta4-5alpha-reductase activity|steroid 5 alpha reductase|3-oxo-5alpha-steroid delta4-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003865 GO:0003864 biolink:MolecularActivity 3-methyl-2-oxobutanoate hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate. RHEA:11824|EC:2.1.2.11|MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN go-plus.json oxopantoate hydroxymethyltransferase activity|5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity|5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity|ketopantoate hydroxymethyltransferase activity|dehydropantoate hydroxymethyltransferase activity|alpha-ketoisovalerate hydroxymethyltransferase activity http://purl.obolibrary.org/obo/GO_0003864 GO:0003867 biolink:MolecularActivity 4-aminobutyrate transaminase activity Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid. RHEA:23352|MetaCyc:GABATRANSAM-RXN|Reactome:R-HSA-916855 go-plus.json gamma-aminobutyric acid transaminase activity|glutamate-succinic semialdehyde transaminase activity|4-aminobutyric acid aminotransferase activity|gamma-aminobutyric transaminase activity|GABA transaminase activity|GABA transferase activity|aminobutyrate transaminase activity|gamma-aminobutyrate aminotransaminase activity|gamma-aminobutyric acid aminotransferase activity|gamma-aminobutyrate transaminase activity|4-aminobutyrate aminotransferase activity|4-aminobutanoate transaminase activity|gamma-amino-N-butyrate transaminase activity|GABA aminotransferase activity|aminobutyrate aminotransferase activity|beta-alanine aminotransferase http://purl.obolibrary.org/obo/GO_0003867 GO:0003866 biolink:MolecularActivity 3-phosphoshikimate 1-carboxyvinyltransferase activity Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate. RHEA:21256|MetaCyc:2.5.1.19-RXN|KEGG_REACTION:R03460|EC:2.5.1.19 go-plus.json phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity|5-enolpyruvylshikimate-3-phosphate synthase activity|3-enol-pyruvoylshikimate-5-phosphate synthase activity|EPSP synthase activity http://purl.obolibrary.org/obo/GO_0003866 GO:0003861 biolink:MolecularActivity 3-isopropylmalate dehydratase activity Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate. EC:4.2.1.33|MetaCyc:3-ISOPROPYLMALISOM-RXN|RHEA:32287 go-plus.json (2R,3S)-3-isopropylmalate hydro-lyase activity|(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)|alpha-isopropylmalate isomerase activity|isopropylmalate isomerase activity|alpha-IPM isomerase activity|beta-isopropylmalate dehydratase activity http://purl.obolibrary.org/obo/GO_0003861 GO:0003860 biolink:MolecularActivity 3-hydroxyisobutyryl-CoA hydrolase activity Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate. RHEA:20888|Reactome:R-HSA-70881|EC:3.1.2.4|MetaCyc:3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN go-plus.json 3-hydroxy-isobutyryl CoA hydrolase activity|HIB CoA deacylase activity|3-hydroxy-2-methylpropanoyl-CoA hydrolase activity http://purl.obolibrary.org/obo/GO_0003860 GO:0003863 biolink:MolecularActivity 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2. RHEA:13457|MetaCyc:1.2.4.4-RXN|EC:1.2.4.4 go-plus.json branched-chain alpha-oxo acid dehydrogenase activity|alpha-oxoisocaproate dehydrogenase activity|3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)|alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity|2-oxoisovalerate (lipoate) dehydrogenase activity|alpha-keto-alpha-methylvalerate dehydrogenase activity|BCKDH activity|3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity|branched-chain keto acid dehydrogenase activity|branched-chain 2-oxo acid dehydrogenase activity|branched-chain ketoacid dehydrogenase activity|2-oxoisocaproate dehydrogenase activity|BCOAD activity|branched-chain (-2-oxoacid) dehydrogenase (BCD) activity|branched-chain 2-keto acid dehydrogenase activity|alpha-ketoisocaproate dehydrogenase activity|alpha-ketoacid dehydrogenase activity|alpha-ketoisovalerate dehydrogenase activity|alpha-ketoisocaproic dehydrogenase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity|branched chain keto acid dehydrogenase activity|dehydrogenase, 2-oxoisovalerate (lipoate) activity|branched-chain alpha-keto acid dehydrogenase activity|dehydrogenase, branched chain alpha-keto acid activity http://purl.obolibrary.org/obo/GO_0003863 GO:0003862 biolink:MolecularActivity 3-isopropylmalate dehydrogenase activity Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+. EC:1.1.1.85|RHEA:32271|MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN go-plus.json beta-IPM dehydrogenase activity|3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity|beta-isopropylmalic enzyme|IPMDH|IMDH activity|beta-isopropylmalate dehydrogenase activity|(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity|threo-Ds-3-isopropylmalate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003862 GO:1904669 biolink:BiologicalProcess ATP export The directed movement of ATP out of a cell or organelle. go-plus.json ATP efflux http://purl.obolibrary.org/obo/GO_1904669 CHEBI:132316 biolink:ChemicalSubstance S-dodecanoyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132316 GO:1904668 biolink:BiologicalProcess positive regulation of ubiquitin protein ligase activity Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity. go-plus.json up regulation of APC-fizzy related complex activity|up-regulation of ubiquitin protein ligase activity|activation of protein ubiquitination activity|positive regulation of protein ubiquitination activity|up-regulation of ubiquitin ligase activity|up-regulation of E3|upregulation of ubiquitin protein ligase activity|activation of APC-Cdc20 complex activity|upregulation of APC-fizzy related complex activity|activation of APC-fizzy related complex activity|activation of E3|upregulation of ubiquitin ligase activity|up-regulation of protein ubiquitination activity|positive regulation of APC-fizzy related complex activity|positive regulation of E3|up regulation of ubiquitin protein ligase activity|up regulation of E3|up-regulation of APC-fizzy related complex activity|activation of ubiquitin protein ligase activity|upregulation of protein ubiquitination activity|up regulation of ubiquitin ligase activity|activation of anaphase-promoting complex activity|activation of ubiquitin ligase activity|positive regulation of ubiquitin ligase activity|upregulation of E3|up regulation of protein ubiquitination activity http://purl.obolibrary.org/obo/GO_1904668 CHEBI:132319 biolink:ChemicalSubstance S-tetradecanoyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132319 GO:1904667 biolink:BiologicalProcess negative regulation of ubiquitin protein ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity. go-plus.json inhibition of ubiquitin protein ligase activity|inhibition of E3|inhibition of ubiquitin ligase activity|negative regulation of anaphase-promoting complex activity during mitotic cell cycle|negative regulation of protein ubiquitination activity|down-regulation of protein ubiquitination activity|negative regulation of cyclosome activity during mitotic cell cycle|negative regulation of APC-Cdc20 complex activity|negative regulation of APC-fizzy related complex activity|negative regulation of APC/C activity during mitotic cell cycle|down regulation of ubiquitin protein ligase activity|inhibition of protein ubiquitination activity|negative regulation of E3|down-regulation of E3|down regulation of ubiquitin ligase activity|downregulation of ubiquitin protein ligase activity|downregulation of ubiquitin ligase activity|downregulation of E3|negative regulation of APC activity during mitotic cell cycle|negative regulation of mitotic anaphase-promoting complex activity|down regulation of protein ubiquitination activity|down-regulation of ubiquitin protein ligase activity|down regulation of E3|negative regulation of ubiquitin ligase activity|down-regulation of ubiquitin ligase activity|downregulation of protein ubiquitination activity http://purl.obolibrary.org/obo/GO_1904667 GO:1904666 biolink:BiologicalProcess regulation of ubiquitin protein ligase activity Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity. go-plus.json regulation of ubiquitin ligase activity|regulation of APC-fizzy related complex activity|regulation of E3|regulation of protein ubiquitination activity http://purl.obolibrary.org/obo/GO_1904666 CHEBI:49156 biolink:ChemicalSubstance (6S)-vomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49156 chebi_ph7_3 GO:1904665 biolink:BiologicalProcess positive regulation of N-terminal peptidyl-methionine acetylation Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_1904665 GO:1904664 biolink:BiologicalProcess negative regulation of N-terminal peptidyl-methionine acetylation Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_1904664 GO:1904663 biolink:BiologicalProcess regulation of N-terminal peptidyl-methionine acetylation Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_1904663 GO:1904673 biolink:BiologicalProcess negative regulation of somatic stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance. go-plus.json downregulation of somatic stem cell population maintenance|down regulation of somatic stem cell population maintenance|inhibition of somatic stem cell population maintenance|down-regulation of somatic stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904673 GO:0062224 biolink:BiologicalProcess positive regulation of somatic muscle development Any process that increases the rate, frequency or extent of somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062224 GO:1904672 biolink:BiologicalProcess regulation of somatic stem cell population maintenance Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance. go-plus.json http://purl.obolibrary.org/obo/GO_1904672 GO:0062223 biolink:BiologicalProcess regulation of somatic muscle development Any process that regulates the rate, frequency or extent of somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062223 GO:1904671 biolink:BiologicalProcess negative regulation of cell differentiation involved in stem cell population maintenance Any negative regulation of cell differentiation that is involved in stem cell population maintenance. go-plus.json negative regulation of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in maintenance of pluripotency|inhibition of cell differentiation involved in stem cell population maintenance|downregulation of cell differentiation involved in maintenance of pluripotency|down regulation of cell differentiation involved in maintenance of pluripotency|down regulation of cell differentiation involved in stem cell population maintenance|downregulation of cell differentiation involved in stem cell population maintenance|inhibition of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in stem cell population maintenance http://purl.obolibrary.org/obo/GO_1904671 GO:0062226 biolink:BiologicalProcess regulation of adult somatic muscle development Any process that modulates the rate, frequency or extent of adult somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062226 CHEBI:132311 biolink:ChemicalSubstance S-hexanoyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132311 GO:1904670 biolink:BiologicalProcess actin filament polymerization involved in mitotic actomyosin contractile ring assembly Any actin filament polymerization that is involved in mitotic actomyosin contractile ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1904670 CHEBI:132310 biolink:ChemicalSubstance S-acyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132310 GO:0062225 biolink:BiologicalProcess negative regulation of somatic muscle development Any process that decreases the rate, frequency or extent of somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062225 CHEBI:132313 biolink:ChemicalSubstance S-decanoyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132313 GO:0062228 biolink:BiologicalProcess negative regulation of adult somatic muscle development Any process that decreases the rate, frequency or extent of adult somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062228 CHEBI:132312 biolink:ChemicalSubstance S-octanoyl-4'-phosphopantetheine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132312 GO:0062227 biolink:BiologicalProcess positive regulation of adult somatic muscle development Any process that increases the rate, frequency or extent of adult somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062227 CHEBI:49161 biolink:ChemicalSubstance (6R)-vomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49161 chebi_ph7_3 GO:0062229 biolink:BiologicalProcess regulation of larval somatic muscle development Any process that modulates the rate, frequency or extent of larval somatic muscle development. go-plus.json http://purl.obolibrary.org/obo/GO_0062229 CHEBI:49160 biolink:ChemicalSubstance (6R,9S)-vomifoliol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49160 chebi_ph7_3 CHEBI:50141 biolink:ChemicalSubstance bronchoconstrictor agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50141 GO:0003869 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003869 GO:0003868 biolink:MolecularActivity 4-hydroxyphenylpyruvate dioxygenase activity Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2. UM-BBD_reactionID:r0298|RHEA:16189|EC:1.13.11.27|MetaCyc:4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN|Reactome:R-HSA-71163 go-plus.json p-hydroxyphenylpyruvate hydroxylase activity|p-hydroxyphenylpyruvic oxidase activity|4-hydroxyphenylpyruvate hydroxylase activity|4-hydroxyphenylpyruvic acid dioxygenase activity|p-hydroxyphenylpyruvic hydroxylase activity|4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)|p-hydroxyphenylpyruvic acid hydroxylase activity|p-hydroxyphenylpyruvate dioxygenase activity|p-hydroxyphenylpyruvate oxidase activity http://purl.obolibrary.org/obo/GO_0003868 CHEBI:74105 biolink:ChemicalSubstance aldono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_74105 chebi_ph7_3 CHEBI:74106 biolink:ChemicalSubstance erucoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74106 CHEBI:74109 biolink:ChemicalSubstance (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74109 CHEBI:64782 biolink:ChemicalSubstance (+)-artemisinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64782 chebi_ph7_3 CHEBI:15809 biolink:ChemicalSubstance dolichyl D-mannosyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15809 CHEBI:64781 biolink:ChemicalSubstance 3-heptaprenyl-sn-glycero-1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64781 chebi_ph7_3 CHEBI:15808 biolink:ChemicalSubstance 12-dehydrotetracycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_15808 CHEBI:64786 biolink:ChemicalSubstance (+)-6-exo-hydroxycamphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64786 chebi_ph7_3 CHEBI:15805 biolink:ChemicalSubstance D-octopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15805 CHEBI:64785 biolink:ChemicalSubstance [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64785 chebi_ph7_3 CHEBI:88752 biolink:ChemicalSubstance cholesteryl (5Z,8Z,11Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88752 chebi_ph7_3 CHEBI:64784 biolink:ChemicalSubstance [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64784 chebi_ph7_3 CHEBI:15807 biolink:ChemicalSubstance beta-L-arabinose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15807 CHEBI:64783 biolink:ChemicalSubstance (+)-artemisinic alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64783 chebi_ph7_3 CHEBI:15801 biolink:ChemicalSubstance (R)-2-hydroxyglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15801 chebi_ph7_3 CHEBI:64789 biolink:ChemicalSubstance 3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64789 chebi_ph7_3 CHEBI:88756 biolink:ChemicalSubstance cholesteryl gamma-linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88756 chebi_ph7_3 CHEBI:64788 biolink:ChemicalSubstance 3,4-dihydro-4-hydroxyphenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64788 chebi_ph7_3 CHEBI:64787 biolink:ChemicalSubstance (+)-6-endo-hydroxycamphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64787 chebi_ph7_3 CHEBI:15802 biolink:ChemicalSubstance alpha,beta-didehydrotryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15802 CHEBI:74100 biolink:ChemicalSubstance N-[(9Z)-octadecenoyl]sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74100 chebi_ph7_3 CHEBI:74116 biolink:ChemicalSubstance 2-hydroxystearoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74116 chebi_ph7_3 CHEBI:74115 biolink:ChemicalSubstance 2-hydroxypalmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74115 chebi_ph7_3 CHEBI:74118 biolink:ChemicalSubstance 2-hydroxytetracosanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74118 chebi_ph7_3 CHEBI:74117 biolink:ChemicalSubstance 2-hydroxybehenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74117 chebi_ph7_3 CHEBI:74119 biolink:ChemicalSubstance (3S)-3-methyl-2-oxo-3-phenylpropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74119 chebi_ph7_3 CHEBI:64793 biolink:ChemicalSubstance 2,2'-dioxospirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64793 chebi_ph7_3 CHEBI:64792 biolink:ChemicalSubstance 2-oxospirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64792 chebi_ph7_3 CHEBI:64791 biolink:ChemicalSubstance tetrahydrotyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64791 chebi_ph7_3 CHEBI:64790 biolink:ChemicalSubstance tetrahydro-4-hydroxyphenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64790 chebi_ph7_3 CHEBI:64797 biolink:ChemicalSubstance alpha-muurolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64797 chebi_ph7_3 CHEBI:64796 biolink:ChemicalSubstance 2-deoxy-scyllo-inosose go-plus.json http://purl.obolibrary.org/obo/CHEBI_64796 chebi_ph7_3 CHEBI:64795 biolink:ChemicalSubstance phytosphingosine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64795 chebi_ph7_3 CHEBI:64794 biolink:ChemicalSubstance salicin-6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64794 chebi_ph7_3 CHEBI:64799 biolink:ChemicalSubstance beta-copaene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64799 chebi_ph7_3 CHEBI:64798 biolink:ChemicalSubstance gamma-muurolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64798 chebi_ph7_3 CHEBI:74114 biolink:ChemicalSubstance (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74114 CHEBI:74127 biolink:ChemicalSubstance (13Z)-3-oxodocosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74127 CHEBI:74126 biolink:ChemicalSubstance (11Z)-eicosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74126 CHEBI:74128 biolink:ChemicalSubstance (15Z)-tetracosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74128 chebi_ph7_3 CHEBI:15827 biolink:ChemicalSubstance N(omega)-(ADP-D-ribosyl)-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15827 CHEBI:15826 biolink:ChemicalSubstance 16alpha-hydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15826 chebi_ph7_3 CHEBI:15829 biolink:ChemicalSubstance L-serine O-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15829 CHEBI:15822 biolink:ChemicalSubstance 17alpha-estradiol 3-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15822 CHEBI:15825 biolink:ChemicalSubstance 3-methylbut-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_15825 chebi_ph7_3 CHEBI:15824 biolink:ChemicalSubstance D-fructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15824 CHEBI:15821 biolink:ChemicalSubstance 5-hydroxy-6-methylpyridine-3-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15821 CHEBI:15820 biolink:ChemicalSubstance GDP-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15820 CHEBI:74120 biolink:ChemicalSubstance Gly-Met go-plus.json http://purl.obolibrary.org/obo/CHEBI_74120 CHEBI:74122 biolink:ChemicalSubstance (3S)-3-methyl-2-oxo-3-phenylpropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_74122 CHEBI:74138 biolink:ChemicalSubstance 2-hydroxystearoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74138 CHEBI:74137 biolink:ChemicalSubstance 2-hydroxyhexadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74137 CHEBI:15819 biolink:ChemicalSubstance N(6)-(dimethylallyl)adenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15819 CHEBI:88764 biolink:ChemicalSubstance ethyl butyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88764 chebi_ph7_3 CHEBI:15816 biolink:ChemicalSubstance D-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15816 CHEBI:15815 biolink:ChemicalSubstance quinolin-4-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15815 chebi_ph7_3 CHEBI:15817 biolink:ChemicalSubstance semiquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15817 CHEBI:15812 biolink:ChemicalSubstance dolichyl beta-D-glucosyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15812 CHEBI:15811 biolink:ChemicalSubstance O-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15811 CHEBI:74130 biolink:ChemicalSubstance N-[(15Z)-tetracosenoyl]sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74130 chebi_ph7_3 CHEBI:74132 biolink:ChemicalSubstance N-[(17Z)-hexacosenoyl]sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74132 chebi_ph7_3 CHEBI:74134 biolink:ChemicalSubstance (17Z)-hexacosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74134 chebi_ph7_3 CHEBI:74133 biolink:ChemicalSubstance (15Z)-3-oxotetracosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74133 CHEBI:74149 biolink:ChemicalSubstance (17Z)-hexacosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74149 CHEBI:74148 biolink:ChemicalSubstance 2-hydroxybehenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74148 GO:0052803 biolink:BiologicalProcess imidazole-containing compound metabolic process The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. go-plus.json imidazole metabolism http://purl.obolibrary.org/obo/GO_0052803 GO:0052802 biolink:BiologicalProcess nitroimidazole metabolic process The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring. go-plus.json nitroimidazole metabolism http://purl.obolibrary.org/obo/GO_0052802 GO:0052801 biolink:BiologicalProcess bicyclic nitroimidazole metabolic process The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring. go-plus.json bicyclic nitroimidazole metabolism http://purl.obolibrary.org/obo/GO_0052801 GO:0052800 biolink:BiologicalProcess bicyclic nitroimidazole catabolic process The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole. go-plus.json bicyclic nitroimidazole breakdown|bicyclic nitroimidazole catabolism|bicyclic nitroimidazole degradation http://purl.obolibrary.org/obo/GO_0052800 GO:0052807 biolink:MolecularActivity aflatoxin reductase (coenzyme F420) activity Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. go-plus.json coenzyme F420-dependent aflatoxin reductase activity|coenzyme F420-aflatoxin reductase activity|aflatoxin:coenzyme F420 oxidoreductase activity|aflatoxin:reduced coenzyme F420 reductase activity http://purl.obolibrary.org/obo/GO_0052807 GO:0052806 biolink:MolecularActivity sulfite reductase (coenzyme F420) activity Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. go-plus.json coenzyme F420-dependent sulfite reductase activity|coenzyme F420-sulfite reductase activity|sulfite:reduced coenzyme F420 reductase activity|hydrogen-sulfide:coenzyme F420 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052806 GO:0052805 biolink:BiologicalProcess imidazole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. go-plus.json imidazole catabolism|imidazole degradation|imidazole breakdown http://purl.obolibrary.org/obo/GO_0052805 GO:0052804 biolink:BiologicalProcess nitroimidazole catabolic process The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring. go-plus.json nitroimidazole degradation|nitroimidazole breakdown|nitroimidazole catabolism http://purl.obolibrary.org/obo/GO_0052804 GO:0052809 biolink:MolecularActivity acharan sulfate lyase activity Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0052809 GO:0052808 biolink:MolecularActivity reduced coenzyme F420:NADP+ oxidoreductase activity Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. EC:1.5.1.40 go-plus.json F420H2:NADP oxidoreductase activity|NADP+:F420 oxidoreductase activity|coenzyme F420-dependent NADP oxidoreductase activity|coenzyme F420-dependent NADP reductase activity|F420H2:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052808 UBERON:0022292 biolink:AnatomicalEntity splenic arteriole go-plus.json http://purl.obolibrary.org/obo/UBERON_0022292 UBERON:0022293 biolink:AnatomicalEntity reproductive gland secretion A portion of organism substance that is secreted by a reproductive gland. go-plus.json genital fluid|reproductive system secretion|reproductive system fluid/secretion|genital secretion|reproductive system fluid http://purl.obolibrary.org/obo/UBERON_0022293 CHEBI:74141 biolink:ChemicalSubstance montanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74141 chebi_ph7_3 CHEBI:74140 biolink:ChemicalSubstance 2-hydroxytetracosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74140 CHEBI:74143 biolink:ChemicalSubstance dTDP-6-deoxy-alpha-D-allose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74143 chebi_ph7_3 CHEBI:74142 biolink:ChemicalSubstance (15Z)-tetracosenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74142 CHEBI:74146 biolink:ChemicalSubstance C24:1-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74146 chebi_ph7_3 GO:0052810 biolink:MolecularActivity 1-phosphatidylinositol-5-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+). Reactome:R-HSA-1675810|Reactome:R-HSA-1675866|RHEA:44680 go-plus.json ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase activity|1-phosphatidylinositol 5-kinase activity http://purl.obolibrary.org/obo/GO_0052810 CHEBI:74159 biolink:ChemicalSubstance D-cycloserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74159 chebi_ph7_3 GO:0052814 biolink:MolecularActivity medium-chain-aldehyde dehydrogenase activity Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons. EC:1.2.1.- go-plus.json medium-chain-aldehyde:NAD+ oxidoreductase activity|medium-chain aliphatic aldehyde dehydrogenase activity|medium-chain fatty aldehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052814 GO:0052813 biolink:MolecularActivity phosphatidylinositol bisphosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052813 GO:0052812 biolink:MolecularActivity phosphatidylinositol-3,4-bisphosphate 5-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+). Reactome:R-HSA-1675773|EC:2.7.1.153 go-plus.json ATP:1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052812 GO:0052811 biolink:MolecularActivity 1-phosphatidylinositol-3-phosphate 4-kinase activity Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+). RHEA:63688|Reactome:R-HSA-1676145 go-plus.json phosphatidylinositol 3-phosphate 4-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 4-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052811 GO:0052818 biolink:MolecularActivity heteroglycan 3-alpha-mannosyltransferase activity Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP. EC:2.4.1.48|MetaCyc:RXN-7992|KEGG_REACTION:R03769 go-plus.json GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase activity|heteropolysaccharide 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 3-alpha-mannosyltransferase activity|GDP mannose 3-alpha-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0052818 GO:0052817 biolink:MolecularActivity very long chain acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18. go-plus.json very long-chain acyl-thioester hydrolase activity|very long-chain-acyl-CoA hydrolase activity|very long-chain acyl coenzyme A hydrolase activity|very long-chain hydrolase activity http://purl.obolibrary.org/obo/GO_0052817 GO:0052816 biolink:MolecularActivity long-chain acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length. go-plus.json long-chain acyl coenzyme A hydrolase activity|long-chain hydrolase activity|long-chain acyl-thioester hydrolase activity|long-chain-acyl-CoA hydrolase activity http://purl.obolibrary.org/obo/GO_0052816 GO:0052815 biolink:MolecularActivity medium-chain acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length. go-plus.json medium-chain acyl coenzyme A hydrolase activity|medium-chain-acyl-CoA hydrolase activity|medium-chain hydrolase activity|medium-chain acyl-thioester hydrolase activity http://purl.obolibrary.org/obo/GO_0052815 GO:0052819 biolink:MolecularActivity heteroglycan 2-alpha-mannosyltransferase activity Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP. KEGG_REACTION:R03768|MetaCyc:2.4.1.48-RXN|EC:2.4.1.48 go-plus.json GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase activity|heteropolysaccharide 2-alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 2-alpha-mannosyltransferase activity|GDP mannose 2-alpha-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0052819 CHEBI:74150 biolink:ChemicalSubstance octacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74150 CHEBI:74151 biolink:ChemicalSubstance S-palmitoyl-L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74151 chebi_ph7_3 CHEBI:74153 biolink:ChemicalSubstance dTDP-5,5-di-C-methyl-beta-L-lyxose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74153 chebi_ph7_3 CHEBI:74156 biolink:ChemicalSubstance 3-amino-4,7-dihydroxycoumarin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74156 chebi_ph7_3 CHEBI:74155 biolink:ChemicalSubstance 3-dimethylallyl-4-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74155 chebi_ph7_3 CHEBI:74158 biolink:ChemicalSubstance O-ureido-D-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74158 chebi_ph7_3 GO:0052821 biolink:MolecularActivity DNA-7-methyladenine glycosylase activity Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site. EC:3.2.2.21|MetaCyc:3.2.2.21-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0052821 GO:0052820 biolink:MolecularActivity DNA-1,N6-ethenoadenine N-glycosylase activity Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. go-plus.json 1,N6-ethenoadenine glycosylase activity|1,N(6)-ethenoadenine N-glycosylase activity http://purl.obolibrary.org/obo/GO_0052820 GO:0052825 biolink:MolecularActivity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate. Reactome:R-HSA-1855219 go-plus.json http://purl.obolibrary.org/obo/GO_0052825 GO:0052824 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052824 GO:0052823 biolink:MolecularActivity 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+. MetaCyc:RXN-12070|UM-BBD_reactionID:r1622|EC:3.7.1.14|RHEA:25046 go-plus.json 2-hydroxy-6-ketonona-2,4,7-trienedoic acid hydrolase activity|(2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate fumarylhydrolase activity http://purl.obolibrary.org/obo/GO_0052823 GO:0052822 biolink:MolecularActivity DNA-3-methylguanine glycosylase activity Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site. EC:3.2.2.21|MetaCyc:3.2.2.21-RXN go-plus.json 3-methylguanine DNA glycosylase I|deoxyribonucleate 3-methylguanine glycosidase I|DNA glycosidase I activity|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine) http://purl.obolibrary.org/obo/GO_0052822 GO:0052829 biolink:MolecularActivity inositol-1,3,4-trisphosphate 1-phosphatase activity Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate. Reactome:R-HSA-1855232 go-plus.json http://purl.obolibrary.org/obo/GO_0052829 GO:0052828 biolink:MolecularActivity inositol-3,4-bisphosphate 4-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate. Reactome:R-HSA-1855202|RHEA:43388 go-plus.json http://purl.obolibrary.org/obo/GO_0052828 GO:0052827 biolink:MolecularActivity inositol pentakisphosphate phosphatase activity Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052827 GO:0052826 biolink:MolecularActivity inositol hexakisphosphate 2-phosphatase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate. EC:3.1.3.62|Reactome:R-HSA-1855225 go-plus.json 1D-myo-inositol-hexakisphosphate 2-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0052826 CHEBI:74161 biolink:ChemicalSubstance C26:1-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74161 chebi_ph7_3 CHEBI:74160 biolink:ChemicalSubstance C24:1-sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74160 chebi_ph7_3 CHEBI:74162 biolink:ChemicalSubstance C26:1-sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74162 chebi_ph7_3 CHEBI:74165 biolink:ChemicalSubstance (E)-1,3-pentadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_74165 chebi_ph7_3 CHEBI:74164 biolink:ChemicalSubstance nitrocyclohexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_74164 chebi_ph7_3 CHEBI:74167 biolink:ChemicalSubstance N-tetracosanoyl-C17-sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74167 chebi_ph7_3 CHEBI:74166 biolink:ChemicalSubstance C17 sphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74166 chebi_ph7_3 CHEBI:74169 biolink:ChemicalSubstance L-alaninamide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74169 chebi_ph7_3 CHEBI:74168 biolink:ChemicalSubstance D-ribono-1,4-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_74168 chebi_ph7_3 GO:0052832 biolink:MolecularActivity inositol monophosphate 3-phosphatase activity Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate. Reactome:R-HSA-1855210|RHEA:30739|EC:3.1.3.25|MetaCyc:MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0052832 GO:0052831 biolink:MolecularActivity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate. Reactome:R-HSA-1855159 go-plus.json http://purl.obolibrary.org/obo/GO_0052831 GO:0052830 biolink:MolecularActivity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate. Reactome:R-HSA-1855171 go-plus.json http://purl.obolibrary.org/obo/GO_0052830 GO:0052836 biolink:MolecularActivity inositol 5-diphosphate pentakisphosphate 5-kinase activity Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate. Reactome:R-HSA-1855158|Reactome:R-HSA-1855224 go-plus.json http://purl.obolibrary.org/obo/GO_0052836 GO:0052835 biolink:MolecularActivity inositol-3,4,6-trisphosphate 1-kinase activity Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+). Reactome:R-HSA-1855169|EC:2.7.1.- go-plus.json 1D-myo-inositol-trisphosphate 1-kinase activity|ATP:1D-myo-inositol-3,4,6-trisphosphate 1-phosphotransferase activity|inositol-trisphosphate 1-kinase activity|ins(3,4,6)P(3) 1-kinase activity|IP3 1-kinase activity|Ins(3,4,6)P3 1-kinase activity|inositol 3,4,6-trisphosphate 1-kinase activity http://purl.obolibrary.org/obo/GO_0052835 GO:0052834 biolink:MolecularActivity inositol monophosphate phosphatase activity Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate. MetaCyc:RXN-10949|RHEA:24056|EC:3.1.3.25 go-plus.json inositol-1(or 4)-monophosphatase activity|myo-inositol monophosphatase activity|myo-inositol phosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|inositol-phosphate phosphatase activity|myo-inositol-phosphate phosphohydrolase activity|L-myo-inositol-phosphate phosphatase activity|myo-inositol-phosphatase activity|inositol phosphatase activity http://purl.obolibrary.org/obo/GO_0052834 GO:0052833 biolink:MolecularActivity inositol monophosphate 4-phosphatase activity Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate. Reactome:R-HSA-1855211|MetaCyc:RXN-10952|RHEA:30735|EC:3.1.3.25 go-plus.json inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|myo-inositol-1(or 4)-monophosphatase activity http://purl.obolibrary.org/obo/GO_0052833 GO:0052839 biolink:MolecularActivity inositol diphosphate tetrakisphosphate kinase activity Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate. Reactome:R-HSA-1855230|Reactome:R-HSA-1855193 go-plus.json http://purl.obolibrary.org/obo/GO_0052839 GO:0052838 biolink:BiologicalProcess thiazole metabolic process The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position. go-plus.json thiazole metabolism http://purl.obolibrary.org/obo/GO_0052838 GO:0052837 biolink:BiologicalProcess thiazole biosynthetic process The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position. go-plus.json thiazole formation|thiazole biosynthesis|thiazole anabolism|thiazole synthesis http://purl.obolibrary.org/obo/GO_0052837 CHEBI:15768 biolink:ChemicalSubstance 3,5-diiodo-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15768 CHEBI:64702 biolink:ChemicalSubstance nucleotide-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64702 CHEBI:15767 biolink:ChemicalSubstance dichloromethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_15767 chebi_ph7_3 CHEBI:15769 biolink:ChemicalSubstance N-[(R)-4-phosphopantothenoyl]-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15769 CHEBI:15764 biolink:ChemicalSubstance anthocyanidin 3,5-diglucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_15764 CHEBI:64705 biolink:ChemicalSubstance aspyridone B go-plus.json http://purl.obolibrary.org/obo/CHEBI_64705 chebi_ph7_3 CHEBI:15763 biolink:ChemicalSubstance nicotinic acid D-ribonucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15763 CHEBI:15766 biolink:ChemicalSubstance N-benzoyl-D-arginine-4-nitroanilide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15766 CHEBI:39737 biolink:ChemicalSubstance D-sorbose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_39737 CHEBI:64704 biolink:ChemicalSubstance aspyridone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64704 chebi_ph7_3 CHEBI:15765 biolink:ChemicalSubstance L-dopa go-plus.json http://purl.obolibrary.org/obo/CHEBI_15765 CHEBI:15760 biolink:ChemicalSubstance tyramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15760 CHEBI:64709 biolink:ChemicalSubstance organic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64709 CHEBI:64708 biolink:ChemicalSubstance one-carbon compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_64708 CHEBI:15761 biolink:ChemicalSubstance N-methylpyridinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_15761 chebi_ph7_3 CHEBI:25105 biolink:ChemicalSubstance macrolide antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_25105 CHEBI:25108 biolink:ChemicalSubstance magnesium molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_25108 CHEBI:25107 biolink:ChemicalSubstance magnesium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_25107 chebi_ph7_3 CHEBI:25106 biolink:ChemicalSubstance macrolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25106 CHEBI:15757 biolink:ChemicalSubstance (S)-4-amino-5-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15757 CHEBI:64712 biolink:ChemicalSubstance trivalent inorganic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_64712 CHEBI:39745 biolink:ChemicalSubstance dihydrogenphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_39745 CHEBI:15756 biolink:ChemicalSubstance hexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15756 CHEBI:64711 biolink:ChemicalSubstance purine nucleotide-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_64711 CHEBI:15759 biolink:ChemicalSubstance 2,3-epoxyphylloquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15759 chebi_ph7_3 CHEBI:15758 biolink:ChemicalSubstance leucocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15758 chebi_ph7_3 CHEBI:64717 biolink:ChemicalSubstance sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64717 chebi_ph7_3 CHEBI:15753 biolink:ChemicalSubstance 2-oxoadipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15753 CHEBI:64716 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64716 chebi_ph7_3 CHEBI:15755 biolink:ChemicalSubstance 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15755 chebi_ph7_3 CHEBI:15754 biolink:ChemicalSubstance 3-O-beta-D-galactopyranosyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15754 chebi_ph7_3 CHEBI:40721 biolink:ChemicalSubstance adenosine 5'-monophosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_40721 CHEBI:64719 biolink:ChemicalSubstance L-argininiumyl(2+) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64719 chebi_ph7_3 CHEBI:15751 biolink:ChemicalSubstance ADP alpha-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_15751 CHEBI:64718 biolink:ChemicalSubstance L-alaniniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64718 chebi_ph7_3 CHEBI:15750 biolink:ChemicalSubstance dolichyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15750 CHEBI:40729 biolink:ChemicalSubstance N-acetyl-beta-D-muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_40729 NCBITaxon:1649845 biolink:OrganismalEntity Yersinia pseudotuberculosis complex go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1649845 CHEBI:64720 biolink:ChemicalSubstance L-alpha-aspartyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64720 chebi_ph7_3 CHEBI:64723 biolink:ChemicalSubstance glyciniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64723 chebi_ph7_3 CHEBI:15789 biolink:ChemicalSubstance 2'-O-methyllicodione go-plus.json http://purl.obolibrary.org/obo/CHEBI_15789 CHEBI:64722 biolink:ChemicalSubstance L-glutaminiumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64722 chebi_ph7_3 CHEBI:64721 biolink:ChemicalSubstance L-alpha-glutamyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64721 chebi_ph7_3 CHEBI:15786 biolink:ChemicalSubstance 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15786 CHEBI:15785 biolink:ChemicalSubstance 1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15785 CHEBI:15788 biolink:ChemicalSubstance 3,5-dichlorocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15788 chebi_ph7_3 CHEBI:64726 biolink:ChemicalSubstance thioselenide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64726 CHEBI:15787 biolink:ChemicalSubstance deoxylimonoic acid D-ring-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15787 CHEBI:15782 biolink:ChemicalSubstance viomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15782 CHEBI:15781 biolink:ChemicalSubstance N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15781 chebi_ph7_3 CHEBI:15784 biolink:ChemicalSubstance N-acetyl-D-glucosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15784 CHEBI:64729 biolink:ChemicalSubstance glutathioselenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64729 CHEBI:15783 biolink:ChemicalSubstance N,N-dimethyl-1,4-phenylenediamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15783 chebi_ph7_3 CHEBI:64731 biolink:ChemicalSubstance L-methioniniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64731 chebi_ph7_3 CHEBI:15779 biolink:ChemicalSubstance N-acyl-D-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15779 CHEBI:15778 biolink:ChemicalSubstance N-acyl-D-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15778 CHEBI:64739 biolink:ChemicalSubstance L-threoniniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64739 chebi_ph7_3 CHEBI:15775 biolink:ChemicalSubstance 3-oxoadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15775 chebi_ph7_3 CHEBI:64738 biolink:ChemicalSubstance L-seriniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64738 chebi_ph7_3 CHEBI:15774 biolink:ChemicalSubstance dTDP-beta-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15774 CHEBI:15777 biolink:ChemicalSubstance 4-oxocyclohexanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15777 chebi_ph7_3 CHEBI:15776 biolink:ChemicalSubstance cephalosporin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_15776 UBERON:2000648 biolink:AnatomicalEntity dorsal fin musculature Musculature that is part of the dorsal fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_2000648 CHEBI:15771 biolink:ChemicalSubstance loganin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15771 chebi_ph7_3 CHEBI:15770 biolink:ChemicalSubstance D-erythritol 4-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15770 CHEBI:15773 biolink:ChemicalSubstance cyclohexylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15773 CHEBI:15772 biolink:ChemicalSubstance L-dopachrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_15772 CHEBI:15728 biolink:ChemicalSubstance 4-guanidinobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15728 CHEBI:64742 biolink:ChemicalSubstance L-asparaginiumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64742 CHEBI:15727 biolink:ChemicalSubstance carnosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15727 CHEBI:64741 biolink:ChemicalSubstance L-valiniumyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64741 chebi_ph7_3 CHEBI:15729 biolink:ChemicalSubstance L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15729 CHEBI:15724 biolink:ChemicalSubstance trimethylamine N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15724 chebi_ph7_3 CHEBI:15723 biolink:ChemicalSubstance 1,6-bis-O-galloyl-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15723 chebi_ph7_3 CHEBI:64745 biolink:ChemicalSubstance phytochelatin 3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64745 CHEBI:64744 biolink:ChemicalSubstance phytochelatin 2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64744 CHEBI:15726 biolink:ChemicalSubstance 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15726 CHEBI:64743 biolink:ChemicalSubstance 2-monolysocardiolipin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64743 chebi_ph7_3 CHEBI:15725 biolink:ChemicalSubstance trimethylenediamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15725 CHEBI:15720 biolink:ChemicalSubstance 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15720 chebi_ph7_3 CHEBI:64747 biolink:ChemicalSubstance phytochelatin 4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64747 CHEBI:15721 biolink:ChemicalSubstance sedoheptulose 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15721 CHEBI:15717 biolink:ChemicalSubstance 4beta-(hydroxymethyl)-4alpha-methyl-5alpha-cholest-7-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15717 chebi_ph7_3 CHEBI:15716 biolink:ChemicalSubstance 12-hydroxydihydrochelirubine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15716 chebi_ph7_3 CHEBI:15718 biolink:ChemicalSubstance 2,3',4,6-tetrahydroxybenzophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15718 CHEBI:15713 biolink:ChemicalSubstance UTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_15713 CHEBI:64757 biolink:ChemicalSubstance 3-palmitoyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64757 chebi_ph7_3 CHEBI:15712 biolink:ChemicalSubstance 2,3-dihydrobiochanin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_15712 chebi_ph7_3 CHEBI:64755 biolink:ChemicalSubstance EDTA(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64755 chebi_ph7_3 CHEBI:15715 biolink:ChemicalSubstance streptomycin 3''-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15715 CHEBI:15714 biolink:ChemicalSubstance trans-sinapic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15714 CHEBI:15711 biolink:ChemicalSubstance 1D-1-O-(indol-3-yl)acetyl-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15711 chebi_ph7_3 CHEBI:15710 biolink:ChemicalSubstance betaine aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15710 chebi_ph7_3 CHEBI:64760 biolink:ChemicalSubstance 3-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64760 chebi_ph7_3 CHEBI:64763 biolink:ChemicalSubstance EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64763 CHEBI:15749 biolink:ChemicalSubstance 3-carboxy-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15749 CHEBI:15746 biolink:ChemicalSubstance spermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15746 CHEBI:64768 biolink:ChemicalSubstance zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64768 CHEBI:64767 biolink:ChemicalSubstance anionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64767 CHEBI:15745 biolink:ChemicalSubstance 2-aminomuconic 6-semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15745 CHEBI:15748 biolink:ChemicalSubstance D-glucuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15748 CHEBI:64766 biolink:ChemicalSubstance cationic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64766 CHEBI:64765 biolink:ChemicalSubstance sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64765 chebi_ph7_3 CHEBI:15742 biolink:ChemicalSubstance pseudotropine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15742 CHEBI:15741 biolink:ChemicalSubstance succinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15741 CHEBI:64769 biolink:ChemicalSubstance organic cationic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64769 CHEBI:15743 biolink:ChemicalSubstance butanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_15743 chebi_ph7_3 UBERON:0022351 biolink:AnatomicalEntity parietal serous membrane Serous membrane layer that lines to a body cavity. go-plus.json cavity lining|parietal wall of serous membrane http://purl.obolibrary.org/obo/UBERON_0022351 UBERON:0022350 biolink:AnatomicalEntity visceral serous membrane Serous membrane layer that is adjacent to and lines an organ. go-plus.json visceral wall of serous membrane http://purl.obolibrary.org/obo/UBERON_0022350 CHEBI:15740 biolink:ChemicalSubstance formate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15740 chebi_ph7_3 OBO:chebi#is_conjugate_base_of biolink:OntologyClass is conjugate base of go-plus.json http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of UBERON:0022355 biolink:AnatomicalEntity basal layer of endometrium The layer of endometrial epithelium adjacent to the uterine cavity. go-plus.json stratum basalis of endometrium|pars basalis of endometrium http://purl.obolibrary.org/obo/UBERON_0022355 UBERON:0022358 biolink:AnatomicalEntity placenta blood vessel A blood vessel of the placenta. go-plus.json placental vessel http://purl.obolibrary.org/obo/UBERON_0022358 CHEBI:64771 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64771 chebi_ph7_3 CHEBI:15739 biolink:ChemicalSubstance isopropylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15739 CHEBI:64775 biolink:ChemicalSubstance organic anionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64775 CHEBI:15738 biolink:ChemicalSubstance staurosporine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15738 CHEBI:15735 biolink:ChemicalSubstance S-formylmycothiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15735 chebi_ph7_3 CHEBI:15734 biolink:ChemicalSubstance primary alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15734 chebi_ph7_3 CHEBI:15737 biolink:ChemicalSubstance N-carbamoylsarcosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15737 CHEBI:64776 biolink:ChemicalSubstance inorganic anionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64776 CHEBI:15730 biolink:ChemicalSubstance pyruvic oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_15730 UBERON:0022360 biolink:AnatomicalEntity male mammary gland duct A mammary gland duct that is part of a male organism. This structure typically regresses. go-plus.json http://purl.obolibrary.org/obo/UBERON_0022360 CHEBI:15733 biolink:ChemicalSubstance N-methylaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_15733 chebi_ph7_3 CHEBI:15732 biolink:ChemicalSubstance phosphonoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15732 UBERON:0022361 biolink:AnatomicalEntity lung field A specific region of the foregut into the area in which the lung will develop. go-plus.json lung field http://purl.obolibrary.org/obo/UBERON_0022361 CHEBI:25179 biolink:ChemicalSubstance melanins go-plus.json http://purl.obolibrary.org/obo/CHEBI_25179 CHEBI:25174 biolink:ChemicalSubstance mannooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25174 GO:1904559 biolink:BiologicalProcess cellular response to dextromethorphan Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904559 GO:1904558 biolink:BiologicalProcess response to dextromethorphan Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904558 GO:1904557 biolink:BiologicalProcess L-alanine transmembrane transport The directed movement of L-alanine across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904557 CHEBI:25171 biolink:ChemicalSubstance mannosyl groups go-plus.json http://purl.obolibrary.org/obo/CHEBI_25171 GO:1904556 biolink:BiologicalProcess L-tryptophan transmembrane transport The directed movement of L-tryptophan across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904556 GO:1904555 biolink:BiologicalProcess L-proline transmembrane transport The directed movement of L-proline across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904555 CHEBI:25176 biolink:ChemicalSubstance mannuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25176 GO:1904554 biolink:BiologicalProcess positive regulation of chemotaxis to arachidonic acid Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid. go-plus.json up regulation of chemotaxis to arachidonic acid|upregulation of chemotaxis to arachidonic acid|up-regulation of chemotaxis to arachidonic acid|activation of chemotaxis to arachidonic acid http://purl.obolibrary.org/obo/GO_1904554 GO:1904553 biolink:BiologicalProcess negative regulation of chemotaxis to arachidonic acid Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid. go-plus.json down-regulation of chemotaxis to arachidonic acid|downregulation of chemotaxis to arachidonic acid|down regulation of chemotaxis to arachidonic acid|inhibition of chemotaxis to arachidonic acid http://purl.obolibrary.org/obo/GO_1904553 CHEBI:25175 biolink:ChemicalSubstance mannuronates go-plus.json http://purl.obolibrary.org/obo/CHEBI_25175 GO:1904563 biolink:BiologicalProcess phosphatidylinositol 5-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate. go-plus.json phosphatidylinositol 5-phosphate formation|phosphatidylinositol 5-phosphate anabolism|phosphatidylinositol 5-phosphate biosynthesis|phosphatidylinositol 5-phosphate synthesis http://purl.obolibrary.org/obo/GO_1904563 GO:1904562 biolink:BiologicalProcess phosphatidylinositol 5-phosphate metabolic process The chemical reactions and pathways involving phosphatidylinositol 5-phosphate. go-plus.json phosphatidylinositol 5-phosphate metabolism http://purl.obolibrary.org/obo/GO_1904562 UBERON:0036925 biolink:AnatomicalEntity wall of eyeball go-plus.json eyeball wall http://purl.obolibrary.org/obo/UBERON_0036925 GO:1904561 biolink:BiologicalProcess cellular response to diphenidol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904561 GO:1904560 biolink:BiologicalProcess response to diphenidol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904560 CHEBI:50130 biolink:ChemicalSubstance monacolin L go-plus.json http://purl.obolibrary.org/obo/CHEBI_50130 chebi_ph7_3 CHEBI:50127 biolink:ChemicalSubstance trifluoromethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50127 chebi_ph7_3 CHEBI:50126 biolink:ChemicalSubstance tetrasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50126 CHEBI:50129 biolink:ChemicalSubstance 2-hydroxyisobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50129 CHEBI:25185 biolink:ChemicalSubstance menaquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_25185 chebi_ph7_3 CHEBI:132416 biolink:ChemicalSubstance O(3)-(N-acetyl-alpha-D-glucosaminyl-poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl]-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132416 chebi_ph7_3 CHEBI:132415 biolink:ChemicalSubstance O(3)-(poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl]-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132415 chebi_ph7_3 GO:1904569 biolink:BiologicalProcess regulation of selenocysteine incorporation Any process that modulates the frequency, rate or extent of selenocysteine incorporation. go-plus.json http://purl.obolibrary.org/obo/GO_1904569 GO:1904568 biolink:BiologicalProcess cellular response to wortmannin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus. go-plus.json cellular response to wartmannin http://purl.obolibrary.org/obo/GO_1904568 GO:1904567 biolink:BiologicalProcess response to wortmannin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus. go-plus.json response to wartmannin http://purl.obolibrary.org/obo/GO_1904567 CHEBI:25189 biolink:ChemicalSubstance 1,4-dimercaptobutane-2,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25189 chebi_ph7_3 GO:1904566 biolink:BiologicalProcess cellular response to 1-oleoyl-sn-glycerol 3-phosphate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus. go-plus.json cellular response to oleoyl lysophosphatidic acid|cellular response to 1-oleoyl lysophosphatidic acid|cellular response to LPA|cellular response to lysophosphatidic acid|cellular response to oleoyl-L-alpha-lysophosphatidic acid http://purl.obolibrary.org/obo/GO_1904566 GO:1904565 biolink:BiologicalProcess response to 1-oleoyl-sn-glycerol 3-phosphate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus. go-plus.json response to oleoyl-L-alpha-lysophosphatidic acid|response to oleoyl lysophosphatidic acid|response to LPA|response to 1-oleoyl lysophosphatidic acid|response to lysophosphatidic acid http://purl.obolibrary.org/obo/GO_1904565 CHEBI:25187 biolink:ChemicalSubstance p-menthan-3-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25187 chebi_ph7_3 GO:1904564 biolink:CellularComponent Nbp35-Cfd1 ATPase complex An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1. go-plus.json http://purl.obolibrary.org/obo/GO_1904564 CHEBI:25186 biolink:ChemicalSubstance p-menthane monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25186 GO:1904574 biolink:BiologicalProcess negative regulation of selenocysteine insertion sequence binding Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding. go-plus.json downregulation of SECIS binding|down regulation of selenocysteine insertion sequence binding|downregulation of selenocysteine insertion sequence binding|negative regulation of SECIS binding|down-regulation of SECIS binding|inhibition of SECIS binding|down-regulation of selenocysteine insertion sequence binding|inhibition of selenocysteine insertion sequence binding|down regulation of SECIS binding http://purl.obolibrary.org/obo/GO_1904574 GO:1904573 biolink:BiologicalProcess regulation of selenocysteine insertion sequence binding Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding. go-plus.json regulation of SECIS binding http://purl.obolibrary.org/obo/GO_1904573 GO:1904572 biolink:BiologicalProcess negative regulation of mRNA binding Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding. go-plus.json down-regulation of mRNA binding|downregulation of mRNA binding|down regulation of mRNA binding|inhibition of mRNA binding http://purl.obolibrary.org/obo/GO_1904572 GO:1904571 biolink:BiologicalProcess positive regulation of selenocysteine incorporation Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation. go-plus.json up-regulation of selenocysteine incorporation|activation of selenocysteine incorporation|up regulation of selenocysteine incorporation|upregulation of selenocysteine incorporation http://purl.obolibrary.org/obo/GO_1904571 GO:1904570 biolink:BiologicalProcess negative regulation of selenocysteine incorporation Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation. go-plus.json down-regulation of selenocysteine incorporation|downregulation of selenocysteine incorporation|down regulation of selenocysteine incorporation|inhibition of selenocysteine incorporation http://purl.obolibrary.org/obo/GO_1904570 CHEBI:50121 biolink:ChemicalSubstance 1,2-thiazolidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50121 chebi_ph7_3 CHEBI:50116 biolink:ChemicalSubstance 4-hydroxy-3-octaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50116 UBERON:0022303 biolink:AnatomicalEntity nervous system cell part layer Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. go-plus.json layer|lamina http://purl.obolibrary.org/obo/UBERON_0022303 CHEBI:50115 biolink:ChemicalSubstance hyponitrite(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50115 CHEBI:50114 biolink:ChemicalSubstance estrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_50114 CHEBI:50113 biolink:ChemicalSubstance androgen go-plus.json http://purl.obolibrary.org/obo/CHEBI_50113 CHEBI:50118 biolink:ChemicalSubstance (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan go-plus.json http://purl.obolibrary.org/obo/CHEBI_50118 chebi_ph7_3 CHEBI:50117 biolink:ChemicalSubstance phenylglyoxylyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_50117 CHEBI:25150 biolink:ChemicalSubstance prunasin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25150 chebi_ph7_3 GO:1904579 biolink:BiologicalProcess cellular response to thapsigargin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904579 GO:1904578 biolink:BiologicalProcess response to thapsigargin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904578 CHEBI:25155 biolink:ChemicalSubstance manganese cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25155 GO:1904577 biolink:BiologicalProcess cellular response to tunicamycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904577 CHEBI:25154 biolink:ChemicalSubstance manganese molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_25154 GO:1904576 biolink:BiologicalProcess response to tunicamycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904576 CHEBI:49125 biolink:ChemicalSubstance N-(beta-D-glucosyl)nicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49125 chebi_ph7_3 GO:1904575 biolink:BiologicalProcess positive regulation of selenocysteine insertion sequence binding Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding. go-plus.json upregulation of selenocysteine insertion sequence binding|up regulation of SECIS binding|activation of SECIS binding|positive regulation of SECIS binding|up regulation of selenocysteine insertion sequence binding|activation of selenocysteine insertion sequence binding|up-regulation of SECIS binding|up-regulation of selenocysteine insertion sequence binding|upregulation of SECIS binding http://purl.obolibrary.org/obo/GO_1904575 CHEBI:49124 biolink:ChemicalSubstance N-(beta-D-glucosyl)nicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49124 GO:1904585 biolink:BiologicalProcess response to putrescine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus. go-plus.json response to tetramethylenediamine|response to 1,4-Butanediamine|response to 1,4-Diaminobutane http://purl.obolibrary.org/obo/GO_1904585 GO:1904584 biolink:BiologicalProcess cellular response to polyamine macromolecule Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus. go-plus.json cellular response to polyamines|cellular response to polyamine http://purl.obolibrary.org/obo/GO_1904584 GO:1904583 biolink:BiologicalProcess response to polyamine macromolecule Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus. go-plus.json response to polyamine|response to polyamines http://purl.obolibrary.org/obo/GO_1904583 GO:1904582 biolink:BiologicalProcess positive regulation of intracellular mRNA localization Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization. go-plus.json up regulation of intracellular mRNA localisation|up-regulation of mRNA localization, intracellular|activation of mRNA localization, intracellular|positive regulation of intracellular mRNA localisation|activation of intracellular mRNA localisation|up-regulation of intracellular mRNA positioning|up-regulation of establishment and maintenance of intracellular RNA localization|up regulation of intracellular mRNA localization|up regulation of mRNA positioning, intracellular|activation of intracellular mRNA localization|positive regulation of mRNA positioning, intracellular|activation of intracellular mRNA positioning|positive regulation of mRNA localization, intracellular|up-regulation of intracellular mRNA localisation|up regulation of mRNA localization, intracellular|activation of mRNA positioning, intracellular|positive regulation of intracellular mRNA positioning|upregulation of establishment and maintenance of intracellular RNA localization|up regulation of intracellular mRNA positioning|up-regulation of intracellular mRNA localization|up-regulation of mRNA positioning, intracellular|upregulation of intracellular mRNA localisation|upregulation of mRNA localization, intracellular|up regulation of establishment and maintenance of intracellular RNA localization|positive regulation of establishment and maintenance of intracellular RNA localization|activation of establishment and maintenance of intracellular RNA localization|upregulation of intracellular mRNA positioning|upregulation of intracellular mRNA localization|upregulation of mRNA positioning, intracellular http://purl.obolibrary.org/obo/GO_1904582 GO:1904581 biolink:BiologicalProcess negative regulation of intracellular mRNA localization Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization. go-plus.json inhibition of intracellular mRNA positioning|down-regulation of establishment and maintenance of intracellular RNA localization|down regulation of mRNA positioning, intracellular|down regulation of intracellular mRNA localization|negative regulation of establishment and maintenance of intracellular RNA localization|downregulation of intracellular mRNA localization|downregulation of mRNA positioning, intracellular|down-regulation of intracellular mRNA localisation|negative regulation of intracellular mRNA localisation|inhibition of establishment and maintenance of intracellular RNA localization|down-regulation of mRNA localization, intracellular|negative regulation of mRNA localization, intracellular|down-regulation of intracellular mRNA positioning|negative regulation of intracellular mRNA positioning|inhibition of intracellular mRNA localisation|negative regulation of mRNA positioning, intracellular|down-regulation of intracellular mRNA localization|down-regulation of mRNA positioning, intracellular|downregulation of mRNA localization, intracellular|inhibition of intracellular mRNA localization|down regulation of establishment and maintenance of intracellular RNA localization|down regulation of mRNA localization, intracellular|downregulation of intracellular mRNA positioning|inhibition of mRNA localization, intracellular|downregulation of establishment and maintenance of intracellular RNA localization|down regulation of intracellular mRNA positioning|down regulation of intracellular mRNA localisation|inhibition of mRNA positioning, intracellular|downregulation of intracellular mRNA localisation http://purl.obolibrary.org/obo/GO_1904581 GO:1904580 biolink:BiologicalProcess regulation of intracellular mRNA localization Any process that modulates the frequency, rate or extent of intracellular mRNA localization. go-plus.json regulation of mRNA positioning, intracellular|regulation of mRNA localization, intracellular|regulation of establishment and maintenance of intracellular RNA localization|regulation of intracellular mRNA positioning|regulation of intracellular mRNA localisation http://purl.obolibrary.org/obo/GO_1904580 CHEBI:40799 biolink:ChemicalSubstance androsta-1,4-diene-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_40799 chebi_ph7_3 CHEBI:50112 biolink:ChemicalSubstance sex hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50112 CHEBI:50111 biolink:ChemicalSubstance deoxycholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_50111 CHEBI:50110 biolink:ChemicalSubstance isopiperitenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50110 chebi_ph7_3 UBERON:0022317 biolink:AnatomicalEntity olfactory cortex layer 1 Surface layer of the olfactory cortex that contains dendrites, fiber systems and a small number of neurons. It has been divided into a superficial part and a deep part. go-plus.json layer 1 of olfactory cortex|olfactory cortex plexiform layer http://purl.obolibrary.org/obo/UBERON_0022317 CHEBI:25169 biolink:ChemicalSubstance mannoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_25169 CHEBI:50103 biolink:ChemicalSubstance excitatory amino acid agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_50103 CHEBI:25168 biolink:ChemicalSubstance mannosylinositol phosphorylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25168 CHEBI:50109 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50109 UBERON:0022318 biolink:AnatomicalEntity olfactory cortex layer 2 Middle layer of olfactory cortex lying deep to layer 1 and superficial to layer 3, characterized by a compact layer of cell bodies. It can be divided into a superficial part and a deep part. go-plus.json layer 2 of olfactory cortex http://purl.obolibrary.org/obo/UBERON_0022318 CHEBI:50108 biolink:ChemicalSubstance 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50108 chebi_ph7_3 CHEBI:50107 biolink:ChemicalSubstance 5beta-scymnol sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50107 CHEBI:50106 biolink:ChemicalSubstance 5beta-scymnol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50106 chebi_ph7_3 CHEBI:49110 biolink:ChemicalSubstance peripheral nervous system drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_49110 GO:1904589 biolink:BiologicalProcess regulation of protein import Any process that modulates the frequency, rate or extent of protein import. go-plus.json regulation of protein uptake http://purl.obolibrary.org/obo/GO_1904589 CHEBI:25167 biolink:ChemicalSubstance mannosaminolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25167 GO:1904588 biolink:BiologicalProcess cellular response to glycoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. go-plus.json cellular response to glycoproteins http://purl.obolibrary.org/obo/GO_1904588 CHEBI:25166 biolink:ChemicalSubstance mannosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25166 GO:1904587 biolink:BiologicalProcess response to glycoprotein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. go-plus.json response to glycoproteins http://purl.obolibrary.org/obo/GO_1904587 CHEBI:25165 biolink:ChemicalSubstance mannosamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25165 GO:1904586 biolink:BiologicalProcess cellular response to putrescine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus. go-plus.json cellular response to tetramethylenediamine|cellular response to 1,4-Butanediamine|cellular response to 1,4-Diaminobutane http://purl.obolibrary.org/obo/GO_1904586 GO:1904596 biolink:BiologicalProcess regulation of connective tissue replacement involved in inflammatory response wound healing Any process that modulates the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing. go-plus.json regulation of fibrosis during inflammatory response|regulation of connective tissue replacement during inflammatory response http://purl.obolibrary.org/obo/GO_1904596 GO:1904595 biolink:BiologicalProcess positive regulation of termination of RNA polymerase II transcription Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription. go-plus.json upregulation of RNA polymerase II transcription termination|up regulation of transcription termination from RNA polymerase II promoter|activation of transcription termination from RNA polymerase II promoter|up-regulation of RNA 3'-end formation by RNA polymerase II|positive regulation of transcription termination from RNA polymerase II promoter|upregulation of RNA polymerase II transcription termination factor activity|upregulation of transcription termination from Pol II promoter|up regulation of RNA polymerase II transcription termination|up regulation of termination of RNA polymerase II transcription|activation of RNA polymerase II transcription termination|positive regulation of RNA polymerase II transcription termination|upregulation of RNA 3'-end formation by RNA polymerase II|up regulation of RNA polymerase II transcription termination factor activity|up-regulation of transcription termination from RNA polymerase II promoter|up-regulation of transcription termination from Pol II promoter|positive regulation of RNA polymerase II transcription termination factor activity|activation of transcription termination from Pol II promoter|upregulation of termination of RNA polymerase II transcription|activation of RNA polymerase II transcription termination factor activity|up regulation of RNA 3'-end formation by RNA polymerase II|up-regulation of RNA polymerase II transcription termination|upregulation of transcription termination from RNA polymerase II promoter|activation of RNA 3'-end formation by RNA polymerase II|positive regulation of RNA 3'-end formation by RNA polymerase II|positive regulation of transcription termination from Pol II promoter|up-regulation of RNA polymerase II transcription termination factor activity|up regulation of transcription termination from Pol II promoter|up-regulation of termination of RNA polymerase II transcription|activation of termination of RNA polymerase II transcription http://purl.obolibrary.org/obo/GO_1904595 GO:1904594 biolink:BiologicalProcess regulation of termination of RNA polymerase II transcription Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription. go-plus.json regulation of transcription termination from Pol II promoter|regulation of RNA polymerase II transcription termination|regulation of RNA polymerase II transcription termination factor activity|regulation of RNA 3'-end formation by RNA polymerase II|regulation of transcription termination from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904594 GO:1904593 biolink:MolecularActivity prostaglandin binding Binding to prostaglandin. go-plus.json http://purl.obolibrary.org/obo/GO_1904593 GO:1904592 biolink:BiologicalProcess positive regulation of protein refolding Any process that activates or increases the frequency, rate or extent of protein refolding. go-plus.json upregulation of heat shock protein activity|upregulation of protein refolding|up regulation of heat shock protein activity|positive regulation of heat shock protein activity|up regulation of protein refolding|activation of protein refolding|activation of heat shock protein activity|up-regulation of heat shock protein activity|up-regulation of protein refolding http://purl.obolibrary.org/obo/GO_1904592 GO:1904591 biolink:BiologicalProcess positive regulation of protein import Any process that activates or increases the frequency, rate or extent of protein import. go-plus.json up-regulation of protein import|activation of protein import|up-regulation of protein uptake|activation of protein uptake|up regulation of protein import|positive regulation of protein uptake|up regulation of protein uptake|upregulation of protein import|upregulation of protein uptake http://purl.obolibrary.org/obo/GO_1904591 GO:1904590 biolink:BiologicalProcess negative regulation of protein import Any process that stops, prevents or reduces the frequency, rate or extent of protein import. go-plus.json down-regulation of protein import|down-regulation of protein uptake|negative regulation of protein uptake|downregulation of protein import|downregulation of protein uptake|down regulation of protein import|inhibition of protein import|down regulation of protein uptake|inhibition of protein uptake http://purl.obolibrary.org/obo/GO_1904590 UBERON:0022320 biolink:AnatomicalEntity dorsal cochlear nucleus pyramidal cell layer go-plus.json http://purl.obolibrary.org/obo/UBERON_0022320 CHEBI:49104 biolink:ChemicalSubstance heteroarenecarbaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_49104 CHEBI:49107 biolink:ChemicalSubstance thiamine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49107 CHEBI:25136 biolink:ChemicalSubstance malonyl-CoAs go-plus.json http://purl.obolibrary.org/obo/CHEBI_25136 CHEBI:49106 biolink:ChemicalSubstance oxepane go-plus.json http://purl.obolibrary.org/obo/CHEBI_49106 chebi_ph7_3 CHEBI:49109 biolink:ChemicalSubstance D-dopachrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_49109 CHEBI:49108 biolink:ChemicalSubstance dopachrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_49108 NCBITaxon:337687 biolink:OrganismalEntity Muroidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_337687 CHEBI:49101 biolink:ChemicalSubstance N-(3,4-dichlorophenyl)malonamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49101 GO:1904599 biolink:MolecularActivity advanced glycation end-product binding Binding to advanced glycation end-product. go-plus.json http://purl.obolibrary.org/obo/GO_1904599 CHEBI:49100 biolink:ChemicalSubstance adenosylcobalamin 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49100 GO:1904598 biolink:BiologicalProcess positive regulation of connective tissue replacement involved in inflammatory response wound healing Any process that activates or increases the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing. go-plus.json activation of connective tissue replacement during inflammatory response|up-regulation of connective tissue replacement involved in inflammatory response wound healing|up regulation of fibrosis during inflammatory response|positive regulation of connective tissue replacement during inflammatory response|positive regulation of fibrosis during inflammatory response|up regulation of connective tissue replacement during inflammatory response|activation of fibrosis during inflammatory response|upregulation of connective tissue replacement involved in inflammatory response wound healing|up-regulation of fibrosis during inflammatory response|upregulation of connective tissue replacement during inflammatory response|up regulation of connective tissue replacement involved in inflammatory response wound healing|activation of connective tissue replacement involved in inflammatory response wound healing|up-regulation of connective tissue replacement during inflammatory response|upregulation of fibrosis during inflammatory response http://purl.obolibrary.org/obo/GO_1904598 CHEBI:49103 biolink:ChemicalSubstance drug metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_49103 GO:1904597 biolink:BiologicalProcess negative regulation of connective tissue replacement involved in inflammatory response wound healing Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing. go-plus.json down regulation of fibrosis during inflammatory response|negative regulation of connective tissue replacement during inflammatory response|down-regulation of connective tissue replacement during inflammatory response|downregulation of fibrosis during inflammatory response|inhibition of connective tissue replacement involved in inflammatory response wound healing|downregulation of connective tissue replacement during inflammatory response|negative regulation of fibrosis during inflammatory response|down-regulation of fibrosis during inflammatory response|down regulation of connective tissue replacement during inflammatory response|down regulation of connective tissue replacement involved in inflammatory response wound healing|downregulation of connective tissue replacement involved in inflammatory response wound healing|inhibition of connective tissue replacement during inflammatory response|inhibition of fibrosis during inflammatory response|down-regulation of connective tissue replacement involved in inflammatory response wound healing http://purl.obolibrary.org/obo/GO_1904597 CHEBI:49102 biolink:ChemicalSubstance malonamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49102 chebi_ph7_3 CHEBI:8359 biolink:ChemicalSubstance pratensein go-plus.json http://purl.obolibrary.org/obo/CHEBI_8359 CHEBI:25147 biolink:ChemicalSubstance mandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25147 chebi_ph7_3 CHEBI:25140 biolink:ChemicalSubstance maltodextrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25140 CHEBI:25143 biolink:ChemicalSubstance maltose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25143 CHEBI:15799 biolink:ChemicalSubstance 1-palmitoyl-sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15799 CHEBI:15793 biolink:ChemicalSubstance 3-hydroxyanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15793 CHEBI:15792 biolink:ChemicalSubstance malonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15792 chebi_ph7_3 CHEBI:15795 biolink:ChemicalSubstance protoaphin aglucone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15795 CHEBI:15794 biolink:ChemicalSubstance juglone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15794 chebi_ph7_3 CHEBI:39785 biolink:ChemicalSubstance 1-pyrroline-2-carboxylic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_39785 chebi_ph7_3 CHEBI:15791 biolink:ChemicalSubstance (S)-2-halocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15791 CHEBI:25115 biolink:ChemicalSubstance malate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25115 CHEBI:40751 biolink:ChemicalSubstance (S)-adrenaline go-plus.json http://purl.obolibrary.org/obo/CHEBI_40751 CHEBI:25111 biolink:ChemicalSubstance magnesium porphyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25111 CHEBI:40753 biolink:ChemicalSubstance 9-anthrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_40753 chebi_ph7_3 CL:0002664 biolink:Cell cardioblast A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. go-plus.json CPC|cardiovascular progenitor cell http://purl.obolibrary.org/obo/CL_0002664 CHEBI:50091 biolink:ChemicalSubstance S-nitrosoglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_50091 CHEBI:74068 biolink:ChemicalSubstance erucoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74068 chebi_ph7_3 CHEBI:132480 biolink:ChemicalSubstance N-icosanoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132480 CHEBI:74069 biolink:ChemicalSubstance (11Z)-eicosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74069 chebi_ph7_3 CHEBI:49097 biolink:ChemicalSubstance (R)-3-aminoisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49097 CHEBI:49096 biolink:ChemicalSubstance 3-aminoisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49096 CL:0002679 biolink:Cell natural helper lymphocyte A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13 go-plus.json http://purl.obolibrary.org/obo/CL_0002679 CHEBI:49098 biolink:ChemicalSubstance (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_49098 CL:0002672 biolink:Cell retinal progenitor cell A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. go-plus.json http://purl.obolibrary.org/obo/CL_0002672 CL:0002671 biolink:Cell endothelial stalk cell An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. go-plus.json http://purl.obolibrary.org/obo/CL_0002671 CL:0002673 biolink:Cell tongue muscle cell A skeletal muscle cell that is part of the tongue. go-plus.json http://purl.obolibrary.org/obo/CL_0002673 CHEBI:74071 biolink:ChemicalSubstance (15Z)-3-oxotetracosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74071 chebi_ph7_3 CL:0002676 biolink:Cell neural crest derived neuroblast A neuroblast derived from a neural crest cell. go-plus.json http://purl.obolibrary.org/obo/CL_0002676 CHEBI:74070 biolink:ChemicalSubstance (13Z)-3-oxodocosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74070 chebi_ph7_3 CHEBI:132499 biolink:ChemicalSubstance fatty acid 16:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132499 CL:0002678 biolink:Cell memory regulatory T cell A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. go-plus.json http://purl.obolibrary.org/obo/CL_0002678 CHEBI:132494 biolink:ChemicalSubstance fatty acid 16:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132494 CHEBI:8382 biolink:ChemicalSubstance prednisone go-plus.json http://purl.obolibrary.org/obo/CHEBI_8382 chebi_ph7_3 CHEBI:49086 biolink:ChemicalSubstance CDP-choline(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49086 CHEBI:49085 biolink:ChemicalSubstance N-acyl-D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49085 CHEBI:49088 biolink:ChemicalSubstance D-tagatofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_49088 chebi_ph7_3 CHEBI:49087 biolink:ChemicalSubstance 2,6-dihydroxynicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49087 CHEBI:50071 biolink:ChemicalSubstance ascopyrone P go-plus.json http://purl.obolibrary.org/obo/CHEBI_50071 chebi_ph7_3 CHEBI:50070 biolink:ChemicalSubstance ascopyrone M go-plus.json http://purl.obolibrary.org/obo/CHEBI_50070 chebi_ph7_3 CHEBI:74081 biolink:ChemicalSubstance 1-archaetidyl-1D-myo-inositol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74081 CHEBI:74084 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74084 chebi_ph7_3 CHEBI:49095 biolink:ChemicalSubstance beta-amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_49095 CHEBI:74083 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74083 chebi_ph7_3 CHEBI:49094 biolink:ChemicalSubstance tagatose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49094 CHEBI:74086 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74086 chebi_ph7_3 CHEBI:50075 biolink:ChemicalSubstance dihydropyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50075 CHEBI:50073 biolink:ChemicalSubstance p-menthadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50073 CHEBI:74087 biolink:ChemicalSubstance (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74087 chebi_ph7_3 CHEBI:50072 biolink:ChemicalSubstance abietadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50072 UBERON:4000115 biolink:AnatomicalEntity mineralized bone tissue Bone tissue mineralized with hydroxyapatite. go-plus.json http://purl.obolibrary.org/obo/UBERON_4000115 CHEBI:50069 biolink:ChemicalSubstance stemar-13-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50069 chebi_ph7_3 GO:1904509 biolink:BiologicalProcess negative regulation of protein localization to basolateral plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane. go-plus.json down regulation of protein localization in basolateral plasma membrane|downregulation of protein localization in basolateral plasma membrane|inhibition of protein localisation to basolateral plasma membrane|down regulation of protein localisation in basolateral plasma membrane|down regulation of protein localization to basolateral plasma membrane|downregulation of protein localisation in basolateral plasma membrane|down-regulation of protein localization in basolateral plasma membrane|negative regulation of protein localization in basolateral plasma membrane|downregulation of protein localization to basolateral plasma membrane|down regulation of protein localisation to basolateral plasma membrane|down-regulation of protein localisation in basolateral plasma membrane|inhibition of protein localization in basolateral plasma membrane|negative regulation of protein localisation in basolateral plasma membrane|downregulation of protein localisation to basolateral plasma membrane|down-regulation of protein localization to basolateral plasma membrane|inhibition of protein localisation in basolateral plasma membrane|down-regulation of protein localisation to basolateral plasma membrane|negative regulation of protein localisation to basolateral plasma membrane|inhibition of protein localization to basolateral plasma membrane http://purl.obolibrary.org/obo/GO_1904509 GO:1904508 biolink:BiologicalProcess regulation of protein localization to basolateral plasma membrane Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane. go-plus.json regulation of protein localization in basolateral plasma membrane|regulation of protein localisation in basolateral plasma membrane|regulation of protein localisation to basolateral plasma membrane http://purl.obolibrary.org/obo/GO_1904508 GO:1904507 biolink:BiologicalProcess positive regulation of telomere maintenance in response to DNA damage Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage. go-plus.json up-regulation of DNA damage response, telomere maintenance|up regulation of telomere maintenance in response to DNA damage|upregulation of DNA damage response, telomere maintenance|upregulation of telomere maintenance in response to DNA damage|up regulation of DNA damage response, telomere maintenance|activation of DNA damage response, telomere maintenance|positive regulation of DNA damage response, telomere maintenance|up-regulation of telomere maintenance in response to DNA damage|activation of telomere maintenance in response to DNA damage http://purl.obolibrary.org/obo/GO_1904507 GO:1904506 biolink:BiologicalProcess negative regulation of telomere maintenance in response to DNA damage Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage. go-plus.json inhibition of DNA damage response, telomere maintenance|down-regulation of telomere maintenance in response to DNA damage|downregulation of telomere maintenance in response to DNA damage|down regulation of DNA damage response, telomere maintenance|down regulation of telomere maintenance in response to DNA damage|downregulation of DNA damage response, telomere maintenance|inhibition of telomere maintenance in response to DNA damage|down-regulation of DNA damage response, telomere maintenance|negative regulation of DNA damage response, telomere maintenance http://purl.obolibrary.org/obo/GO_1904506 CHEBI:49075 biolink:ChemicalSubstance 2-formylglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49075 GO:1904505 biolink:BiologicalProcess regulation of telomere maintenance in response to DNA damage Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage. go-plus.json regulation of DNA damage response, telomere maintenance http://purl.obolibrary.org/obo/GO_1904505 CL:0002658 biolink:Cell glandular cell of the large intestine A glandular epithelial cell of the large intestine. go-plus.json http://purl.obolibrary.org/obo/CL_0002658 GO:1904504 biolink:BiologicalProcess positive regulation of lipophagy Any process that activates or increases the frequency, rate or extent of lipophagy. go-plus.json up regulation of lipophagy|activation of lipophagy|up-regulation of lipophagy|upregulation of lipophagy http://purl.obolibrary.org/obo/GO_1904504 CL:0002657 biolink:Cell glandular cell of esophagus A glandular epithelial cell of the esophagus. go-plus.json http://purl.obolibrary.org/obo/CL_0002657 CHEBI:49077 biolink:ChemicalSubstance 2-hydroxymethylglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49077 GO:1904503 biolink:BiologicalProcess negative regulation of lipophagy Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy. go-plus.json down-regulation of lipophagy|inhibition of lipophagy|down regulation of lipophagy|downregulation of lipophagy http://purl.obolibrary.org/obo/GO_1904503 CL:0002659 biolink:Cell glandular cell of stomach A glandular epithelial cell that is part of the stomach. go-plus.json http://purl.obolibrary.org/obo/CL_0002659 GO:1904502 biolink:BiologicalProcess regulation of lipophagy Any process that modulates the frequency, rate or extent of lipophagy. go-plus.json http://purl.obolibrary.org/obo/GO_1904502 GO:1904501 biolink:BiologicalProcess obsolete positive regulation of chromatin-mediated maintenance of transcription OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription. go-plus.json up regulation of chromatin-mediated maintenance of transcription|activation of chromatin-mediated maintenance of transcription|up-regulation of chromatin-mediated maintenance of transcription|upregulation of chromatin-mediated maintenance of transcription http://purl.obolibrary.org/obo/GO_1904501 GO:1904500 biolink:BiologicalProcess obsolete negative regulation of chromatin-mediated maintenance of transcription OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription. go-plus.json down-regulation of chromatin-mediated maintenance of transcription|inhibition of chromatin-mediated maintenance of transcription|down regulation of chromatin-mediated maintenance of transcription|downregulation of chromatin-mediated maintenance of transcription http://purl.obolibrary.org/obo/GO_1904500 CHEBI:132474 biolink:ChemicalSubstance fatty acid-taurine conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132474 CHEBI:132473 biolink:ChemicalSubstance 13-hydroxytetradecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132473 CHEBI:49080 biolink:ChemicalSubstance marmesin go-plus.json http://purl.obolibrary.org/obo/CHEBI_49080 chebi_ph7_3 CHEBI:132476 biolink:ChemicalSubstance N-tetradecanoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132476 CHEBI:132475 biolink:ChemicalSubstance N-dodecanoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132475 CHEBI:50060 biolink:ChemicalSubstance ent-cassa-12,15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50060 chebi_ph7_3 CHEBI:132477 biolink:ChemicalSubstance N-hexadecanoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132477 CHEBI:49081 biolink:ChemicalSubstance 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49081 CHEBI:49084 biolink:ChemicalSubstance N-acyl-D-glutamates(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49084 CHEBI:74095 biolink:ChemicalSubstance polyprenyl phospho polysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_74095 CHEBI:132479 biolink:ChemicalSubstance N-stearoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132479 CHEBI:74094 biolink:ChemicalSubstance 3-O-phospho-[2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->]n-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74094 CHEBI:74097 biolink:ChemicalSubstance 3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74097 CHEBI:50064 biolink:ChemicalSubstance ent-pimara-9(11),15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50064 chebi_ph7_3 CHEBI:50063 biolink:ChemicalSubstance ent-pimara-8(14),15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50063 chebi_ph7_3 CHEBI:8386 biolink:ChemicalSubstance pregnane go-plus.json http://purl.obolibrary.org/obo/CHEBI_8386 chebi_ph7_3 CHEBI:50062 biolink:ChemicalSubstance pimaradiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50062 CHEBI:50061 biolink:ChemicalSubstance ent-sandaracopimara-8(14),15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50061 chebi_ph7_3 CHEBI:74098 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74098 CHEBI:50068 biolink:ChemicalSubstance stemod-13(17)-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50068 chebi_ph7_3 CHEBI:50067 biolink:ChemicalSubstance 9beta-pimara-7,15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50067 chebi_ph7_3 CHEBI:50065 biolink:ChemicalSubstance D-cystine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50065 GO:0003997 biolink:MolecularActivity acyl-CoA oxidase activity Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide. Reactome:R-HSA-2066787|RHEA:38959|Reactome:R-HSA-390256|Reactome:R-HSA-193369|MetaCyc:ACYL-COA-OXIDASE-RXN|EC:1.3.3.6|Reactome:R-HSA-192335 go-plus.json acyl coenzyme A oxidase activity|fatty acyl-CoA oxidase activity|acyl-CoA:oxygen 2-oxidoreductase activity|fatty acyl-coenzyme A oxidase activity http://purl.obolibrary.org/obo/GO_0003997 GO:0003996 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003996 GO:0003999 biolink:MolecularActivity adenine phosphoribosyltransferase activity Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. MetaCyc:ADENPRIBOSYLTRAN-RXN|RHEA:16609|Reactome:R-HSA-74213|EC:2.4.2.7 go-plus.json adenylic pyrophosphorylase activity|transphosphoribosidase activity|AMP:diphosphate phospho-D-ribosyltransferase activity|AMP pyrophosphorylase activity|AMP diphosphorylase activity|adenine phosphoribosylpyrophosphate transferase activity|AMP-pyrophosphate phosphoribosyltransferase activity|adenosine phosphoribosyltransferase activity|APRT activity|adenylate pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0003999 CHEBI:50059 biolink:ChemicalSubstance imidazolium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_50059 GO:0003998 biolink:MolecularActivity acylphosphatase activity Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate. RHEA:14965|EC:3.6.1.7|MetaCyc:ACYLPHOSPHATASE-RXN go-plus.json 1,3-diphosphoglycerate phosphatase activity|acetylphosphatase activity|GP 1-3|Ho 1-3|acylphosphate phosphohydrolase activity|acetic phosphatase activity http://purl.obolibrary.org/obo/GO_0003998 CHEBI:50058 biolink:ChemicalSubstance L-cystine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50058 chebi_ph7_3 GO:0003993 biolink:MolecularActivity acid phosphatase activity Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum. Reactome:R-HSA-196950|MetaCyc:ACID-PHOSPHATASE-RXN|EC:3.1.3.2 go-plus.json acid monophosphatase activity|uteroferrin|orthophosphoric-monoester phosphohydrolase (acid optimum)|acid phosphomonoester hydrolase activity|phosphate-monoester phosphohydrolase (acid optimum)|acid nucleoside diphosphate phosphatase activity|acid phosphomonoesterase activity|glycerophosphatase activity|acid phosphohydrolase activity|phosphomonoesterase activity http://purl.obolibrary.org/obo/GO_0003993 GO:1904519 biolink:BiologicalProcess protein localization to microtubule minus-end A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end. go-plus.json protein localisation in microtubule minus-end|protein localisation to microtubule minus-end|protein localization in microtubule minus-end http://purl.obolibrary.org/obo/GO_1904519 GO:0003992 biolink:MolecularActivity N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. EC:2.6.1.11|RHEA:18049|KEGG_REACTION:R02283|MetaCyc:ACETYLORNTRANSAM-RXN go-plus.json succinylornithine aminotransferase activity|N-acetylornithine aminotransferase activity|ACOAT activity|N2-acetylornithine 5-aminotransferase activity|N(2)-acetylornithine 5-transaminase activity|acetylornithine delta-transaminase activity|acetylornithine aminotransferase activity|N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity|N2-acetylornithine 5-transaminase activity|N-acetylornithine-delta-transaminase activity|2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|acetylornithine transaminase activity|acetylornithine 5-aminotransferase activity http://purl.obolibrary.org/obo/GO_0003992 GO:1904518 biolink:BiologicalProcess protein localization to cytoplasmic microtubule plus-end A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end. go-plus.json protein localisation to cytoplasmic microtubule plus-end|protein localisation in cytoplasmic microtubule plus-end|protein localization in cytoplasmic microtubule plus-end http://purl.obolibrary.org/obo/GO_1904518 GO:0003995 biolink:MolecularActivity acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Reactome:R-HSA-77274|Reactome:R-HSA-77319|Reactome:R-HSA-77338|Reactome:R-HSA-77327|Reactome:R-HSA-109341|Reactome:R-HSA-77345|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|MetaCyc:ACYLCOADEHYDROG-RXN|Reactome:R-HSA-5695980|Reactome:R-HSA-70859|Reactome:R-HSA-77263|Reactome:R-HSA-70800|EC:1.3.99.3|Reactome:R-HSA-77299|Reactome:R-HSA-5695989 go-plus.json acyl-CoA reductase activity|acyl-CoA:(acceptor) 2,3-oxidoreductase activity|general acyl CoA dehydrogenase activity|long-chain acyl coenzyme A dehydrogenase activity|medium-chain acyl-CoA dehydrogenase activity|acyl CoA dehydrogenase activity|fatty-acyl-CoA dehydrogenase activity|acyl-CoA:acceptor 2,3-oxidoreductase activity|long-chain acyl-CoA dehydrogenase activity|medium-chain acyl-coenzyme A dehydrogenase activity|acyl dehydrogenase activity|fatty acyl coenzyme A dehydrogenase activity|acyl coenzyme A dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003995 GO:0003994 biolink:MolecularActivity aconitate hydratase activity Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. RHEA:10336|EC:4.2.1.3|Reactome:R-HSA-450975|Reactome:R-HSA-70971|Reactome:R-HSA-5690911 go-plus.json citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|cis-aconitase activity|citrate(isocitrate) hydro-lyase activity|aconitase activity|citrate hydro-lyase activity http://purl.obolibrary.org/obo/GO_0003994 GO:1904517 biolink:MolecularActivity MgATP(2-) binding Binding to MgATP(2-). go-plus.json http://purl.obolibrary.org/obo/GO_1904517 CHEBI:25097 biolink:ChemicalSubstance lyxose go-plus.json http://purl.obolibrary.org/obo/CHEBI_25097 CHEBI:132449 biolink:ChemicalSubstance wax ester 36:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132449 chebi_ph7_3 GO:1904516 biolink:BiologicalProcess myofibroblast cell apoptotic process Any apoptotic process in a myofibroblast cell. go-plus.json MFB apoptosis|MFB apoptotic process|myofibroblast cell apoptosis http://purl.obolibrary.org/obo/GO_1904516 CL:0002625 biolink:Cell seminiferous tubule epithelial cell A cell of the seminiferous tubule epithelium. go-plus.json http://purl.obolibrary.org/obo/CL_0002625 CHEBI:49064 biolink:ChemicalSubstance 4-phosphothreonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49064 GO:1904515 biolink:BiologicalProcess positive regulation of TORC2 signaling Any process that activates or increases the frequency, rate or extent of TORC2 signaling. go-plus.json up-regulation of TORC2 signal transduction|upregulation of TORC2 signaling|upregulation of TORC2 signal transduction|up regulation of TORC2 signaling|activation of TORC2 signaling|up regulation of TORC2 signal transduction|activation of TORC2 signal transduction|positive regulation of TORC2 signal transduction|up-regulation of TORC2 signaling http://purl.obolibrary.org/obo/GO_1904515 GO:1904514 biolink:BiologicalProcess positive regulation of initiation of premeiotic DNA replication Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication. go-plus.json positive regulation of initiation of meiotic DNA synthesis|activation of initiation of premeiotic DNA synthesis|up regulation of premeiotic DNA replication initiation|activation of premeiotic DNA replication initiation|positive regulation of initiation of premeiotic DNA synthesis|upregulation of meiotic DNA replication initiation|activation of initiation of meiotic DNA synthesis|positive regulation of premeiotic DNA replication initiation|up regulation of initiation of premeiotic DNA synthesis|up regulation of initiation of premeiotic DNA replication|up-regulation of initiation of meiotic DNA synthesis|up-regulation of meiotic DNA replication initiation|up-regulation of premeiotic DNA replication initiation|upregulation of initiation of premeiotic DNA synthesis|upregulation of initiation of meiotic DNA synthesis|upregulation of initiation of premeiotic DNA replication|activation of meiotic DNA replication initiation|positive regulation of meiotic DNA replication initiation|upregulation of premeiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA synthesis|up regulation of meiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA replication|up regulation of initiation of meiotic DNA synthesis|activation of initiation of premeiotic DNA replication http://purl.obolibrary.org/obo/GO_1904514 GO:0003991 biolink:MolecularActivity acetylglutamate kinase activity Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate. RHEA:14629|MetaCyc:ACETYLGLUTKIN-RXN|EC:2.7.2.8 go-plus.json acetylglutamate phosphokinase activity|N-acetylglutamate phosphokinase activity|N-acetylglutamate kinase activity|N-acetylglutamate 5-phosphotransferase activity|ATP:N-acetyl-L-glutamate 5-phosphotransferase activity|N-acetylglutamic 5-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0003991 NCBITaxon:2611341 biolink:OrganismalEntity Metamonada go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2611341 CHEBI:25095 biolink:ChemicalSubstance L-lysine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_25095 GO:1904513 biolink:BiologicalProcess negative regulation of initiation of premeiotic DNA replication Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication. go-plus.json downregulation of premeiotic DNA replication initiation|negative regulation of initiation of premeiotic DNA synthesis|down-regulation of initiation of premeiotic DNA synthesis|down regulation of meiotic DNA replication initiation|down-regulation of initiation of premeiotic DNA replication|negative regulation of initiation of meiotic DNA synthesis|down-regulation of initiation of meiotic DNA synthesis|inhibition of meiotic DNA replication initiation|down-regulation of premeiotic DNA replication initiation|negative regulation of premeiotic DNA replication initiation|downregulation of initiation of premeiotic DNA synthesis|downregulation of initiation of premeiotic DNA replication|down regulation of initiation of premeiotic DNA synthesis|inhibition of premeiotic DNA replication initiation|inhibition of initiation of meiotic DNA synthesis|down regulation of initiation of premeiotic DNA replication|inhibition of initiation of premeiotic DNA replication|down-regulation of meiotic DNA replication initiation|inhibition of initiation of premeiotic DNA synthesis|negative regulation of meiotic DNA replication initiation|down regulation of initiation of meiotic DNA synthesis|downregulation of initiation of meiotic DNA synthesis|down regulation of premeiotic DNA replication initiation|downregulation of meiotic DNA replication initiation http://purl.obolibrary.org/obo/GO_1904513 GO:0003990 biolink:MolecularActivity acetylcholinesterase activity Catalysis of the reaction: acetylcholine + H2O = choline + acetate. EC:3.1.1.7|RHEA:17561|MetaCyc:ACETYLCHOLINESTERASE-RXN|Reactome:R-HSA-372519 go-plus.json acetylthiocholinesterase activity|choline esterase I activity|acetylcholine acetylhydrolase activity|AcCholE|acetylcholine hydrolase activity|true cholinesterase activity|acetyl.beta-methylcholinesterase activity http://purl.obolibrary.org/obo/GO_0003990 goslim_chembl CHEBI:25094 biolink:ChemicalSubstance lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25094 CHEBI:49065 biolink:ChemicalSubstance phosphothreonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49065 GO:1904512 biolink:BiologicalProcess regulation of initiation of premeiotic DNA replication Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication. go-plus.json regulation of initiation of premeiotic DNA synthesis|regulation of initiation of meiotic DNA synthesis|regulation of premeiotic DNA replication initiation|regulation of meiotic DNA replication initiation http://purl.obolibrary.org/obo/GO_1904512 CL:0002629 biolink:Cell mature microglial cell A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation. go-plus.json mature microglia|reactive microglia|activated microglia http://purl.obolibrary.org/obo/CL_0002629 GO:1904511 biolink:CellularComponent cytoplasmic microtubule plus-end Any microtubule plus-end that is part of a cytoplasmic microtubule. go-plus.json microtubule plus end of non-spindle-associated astral microtubule|microtubule plus end of cytoplasmic microtubule|growing microtubule plus end of non-spindle-associated astral microtubule|growing microtubule plus end of cytoplasmic microtubule|microtubule plus-end of cytoplasmic microtubule|microtubule plus-end of non-spindle-associated astral microtubule http://purl.obolibrary.org/obo/GO_1904511 GO:1904510 biolink:BiologicalProcess positive regulation of protein localization to basolateral plasma membrane Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane. go-plus.json up regulation of protein localisation to basolateral plasma membrane|positive regulation of protein localisation to basolateral plasma membrane|activation of protein localisation to basolateral plasma membrane|up-regulation of protein localisation in basolateral plasma membrane|upregulation of protein localization in basolateral plasma membrane|up-regulation of protein localization to basolateral plasma membrane|upregulation of protein localisation in basolateral plasma membrane|up-regulation of protein localisation to basolateral plasma membrane|upregulation of protein localization to basolateral plasma membrane|up regulation of protein localization in basolateral plasma membrane|positive regulation of protein localization in basolateral plasma membrane|activation of protein localization in basolateral plasma membrane|upregulation of protein localisation to basolateral plasma membrane|up regulation of protein localisation in basolateral plasma membrane|positive regulation of protein localisation in basolateral plasma membrane|activation of protein localisation in basolateral plasma membrane|up regulation of protein localization to basolateral plasma membrane|activation of protein localization to basolateral plasma membrane|up-regulation of protein localization in basolateral plasma membrane http://purl.obolibrary.org/obo/GO_1904510 CHEBI:49069 biolink:ChemicalSubstance 4-phospho-D-threonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49069 CHEBI:49071 biolink:ChemicalSubstance 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49071 CL:0002620 biolink:Cell skin fibroblast A fibroblast of skin. go-plus.json http://purl.obolibrary.org/obo/CL_0002620 CHEBI:49070 biolink:ChemicalSubstance 3-[(5R,6S)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49070 CL:0002623 biolink:Cell acinar cell of salivary gland An acinar cell of salivary gland. go-plus.json http://purl.obolibrary.org/obo/CL_0002623 CHEBI:49072 biolink:ChemicalSubstance (R)-2,3-dihydroxy-3-methylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49072 chebi_ph7_3 CL:0002622 biolink:Cell prostate stromal cell A stromal cell of the prostate. go-plus.json http://purl.obolibrary.org/obo/CL_0002622 CHEBI:50051 biolink:ChemicalSubstance cystine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50051 CL:1000090 biolink:Cell pronephric nephron tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000090 CHEBI:50048 biolink:ChemicalSubstance phenylethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50048 CHEBI:50047 biolink:ChemicalSubstance organic amino compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_50047 GO:1904529 biolink:BiologicalProcess regulation of actin filament binding Any process that modulates the frequency, rate or extent of actin filament binding. go-plus.json regulation of F-actin binding|regulation of actin cross-linking activity http://purl.obolibrary.org/obo/GO_1904529 GO:1904528 biolink:BiologicalProcess positive regulation of microtubule binding Any process that activates or increases the frequency, rate or extent of microtubule binding. go-plus.json up-regulation of microtubule severing activity|upregulation of microtubule/chromatin interaction|up regulation of microtubule binding|upregulation of microtubule severing activity|activation of microtubule binding|up regulation of microtubule/chromatin interaction|positive regulation of microtubule/chromatin interaction|activation of microtubule/chromatin interaction|up regulation of microtubule severing activity|up-regulation of microtubule binding|positive regulation of microtubule severing activity|up-regulation of microtubule/chromatin interaction|activation of microtubule severing activity|upregulation of microtubule binding http://purl.obolibrary.org/obo/GO_1904528 GO:1904527 biolink:BiologicalProcess negative regulation of microtubule binding Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding. go-plus.json down regulation of microtubule binding|down regulation of microtubule/chromatin interaction|downregulation of microtubule binding|inhibition of microtubule severing activity|downregulation of microtubule/chromatin interaction|down regulation of microtubule severing activity|down-regulation of microtubule binding|downregulation of microtubule severing activity|down-regulation of microtubule/chromatin interaction|negative regulation of microtubule/chromatin interaction|inhibition of microtubule binding|negative regulation of microtubule severing activity|down-regulation of microtubule severing activity|inhibition of microtubule/chromatin interaction http://purl.obolibrary.org/obo/GO_1904527 GO:1904526 biolink:BiologicalProcess regulation of microtubule binding Any process that modulates the frequency, rate or extent of microtubule binding. go-plus.json regulation of microtubule/chromatin interaction|regulation of microtubule severing activity http://purl.obolibrary.org/obo/GO_1904526 CHEBI:49052 biolink:ChemicalSubstance ureidocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49052 GO:1904525 biolink:BiologicalProcess positive regulation of DNA amplification Any process that activates or increases the frequency, rate or extent of DNA amplification. go-plus.json upregulation of DNA amplification|up regulation of DNA amplification|activation of DNA amplification|up-regulation of DNA amplification http://purl.obolibrary.org/obo/GO_1904525 CHEBI:49055 biolink:ChemicalSubstance 4-phosphoerythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49055 NCBITaxon:2611352 biolink:OrganismalEntity Discoba go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2611352 GO:1904524 biolink:BiologicalProcess negative regulation of DNA amplification Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification. go-plus.json down regulation of DNA amplification|downregulation of DNA amplification|down-regulation of DNA amplification|inhibition of DNA amplification http://purl.obolibrary.org/obo/GO_1904524 GO:1904523 biolink:BiologicalProcess regulation of DNA amplification Any process that modulates the frequency, rate or extent of DNA amplification. go-plus.json http://purl.obolibrary.org/obo/GO_1904523 CHEBI:49057 biolink:ChemicalSubstance (all-E)-deca-2,4,6,8-tetraenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49057 CL:0002639 biolink:Cell amniotic stem cell An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone go-plus.json http://purl.obolibrary.org/obo/CL_0002639 GO:1904522 biolink:BiologicalProcess positive regulation of myofibroblast cell apoptotic process Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process. go-plus.json up regulation of MFB apoptotic process|upregulation of myofibroblast cell apoptotic process|activation of MFB apoptosis|activation of MFB apoptotic process|positive regulation of MFB apoptotic process|up-regulation of myofibroblast cell apoptosis|up-regulation of MFB apoptosis|up-regulation of myofibroblast cell apoptotic process|activation of myofibroblast cell apoptosis|activation of myofibroblast cell apoptotic process|up-regulation of MFB apoptotic process|positive regulation of myofibroblast cell apoptosis|up regulation of myofibroblast cell apoptosis|upregulation of MFB apoptosis|upregulation of MFB apoptotic process|up regulation of myofibroblast cell apoptotic process|upregulation of myofibroblast cell apoptosis|up regulation of MFB apoptosis|positive regulation of MFB apoptosis http://purl.obolibrary.org/obo/GO_1904522 CHEBI:49056 biolink:ChemicalSubstance 4-phospho-L-erythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49056 GO:1904521 biolink:BiologicalProcess negative regulation of myofibroblast cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process. go-plus.json inhibition of myofibroblast cell apoptotic process|inhibition of myofibroblast cell apoptosis|down-regulation of MFB apoptosis|negative regulation of MFB apoptosis|negative regulation of MFB apoptotic process|down-regulation of MFB apoptotic process|negative regulation of myofibroblast cell apoptosis|down-regulation of myofibroblast cell apoptosis|inhibition of MFB apoptosis|inhibition of MFB apoptotic process|down-regulation of myofibroblast cell apoptotic process|down regulation of MFB apoptosis|downregulation of myofibroblast cell apoptosis|down regulation of myofibroblast cell apoptosis|downregulation of MFB apoptosis|down regulation of MFB apoptotic process|downregulation of myofibroblast cell apoptotic process|down regulation of myofibroblast cell apoptotic process|downregulation of MFB apoptotic process http://purl.obolibrary.org/obo/GO_1904521 CHEBI:49059 biolink:ChemicalSubstance D-threonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49059 GO:1904520 biolink:BiologicalProcess regulation of myofibroblast cell apoptotic process Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process. go-plus.json regulation of MFB apoptosis|regulation of myofibroblast cell apoptosis|regulation of MFB apoptotic process http://purl.obolibrary.org/obo/GO_1904520 CHEBI:49058 biolink:ChemicalSubstance L-erythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49058 GO:1904530 biolink:BiologicalProcess negative regulation of actin filament binding Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding. go-plus.json inhibition of F-actin binding|downregulation of actin cross-linking activity|down regulation of actin cross-linking activity|down regulation of F-actin binding|down-regulation of actin filament binding|inhibition of actin cross-linking activity|downregulation of F-actin binding|downregulation of actin filament binding|negative regulation of F-actin binding|down-regulation of F-actin binding|negative regulation of actin cross-linking activity|down-regulation of actin cross-linking activity|down regulation of actin filament binding|inhibition of actin filament binding http://purl.obolibrary.org/obo/GO_1904530 CL:0002630 biolink:Cell actinomycete-type spore A spore formed from bacteria in the order Actinomycetales. go-plus.json http://purl.obolibrary.org/obo/CL_0002630 CL:0002632 biolink:Cell epithelial cell of lower respiratory tract go-plus.json http://purl.obolibrary.org/obo/CL_0002632 CHEBI:49060 biolink:ChemicalSubstance 2,3,4-trihydroxybutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49060 CHEBI:49062 biolink:ChemicalSubstance tetronic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49062 CL:0002633 biolink:Cell respiratory basal cell A basal cell in the respiratory tract. go-plus.json airway basal cell|airway basal stem cell http://purl.obolibrary.org/obo/CL_0002633 CHEBI:49061 biolink:ChemicalSubstance 2,3,4-trihydroxybutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49061 CHEBI:50042 biolink:ChemicalSubstance alpha-thujone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50042 CHEBI:50041 biolink:ChemicalSubstance thujane monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50041 CHEBI:156403 biolink:ChemicalSubstance hydroperoxy fatty amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_156403 CHEBI:50040 biolink:ChemicalSubstance thujone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50040 chebi_ph7_3 CHEBI:50043 biolink:ChemicalSubstance (+)-alpha-thujone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50043 chebi_ph7_3 GO:0003975 biolink:MolecularActivity UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol. Reactome:R-HSA-4549334|Reactome:R-HSA-446191|RHEA:13289|EC:2.7.8.15|MetaCyc:2.7.8.15-RXN go-plus.json UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity|chitobiosylpyrophosphoryldolichol synthase activity|GlcNAc-1-P transferase activity|UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity|UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity|UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity|uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity|dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity|N-acetylglucosamine-1-phosphate transferase activity http://purl.obolibrary.org/obo/GO_0003975 GO:0003974 biolink:MolecularActivity UDP-N-acetylglucosamine 4-epimerase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine. RHEA:20517|EC:5.1.3.7|MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN go-plus.json UDP-GlcNAc 4-epimerase activity|uridine diphosphate N-acetylglucosamine-4-epimerase activity|UDP acetylglucosamine epimerase activity|uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity|uridine diphosphoacetylglucosamine epimerase activity|UDP-N-acetyl-D-glucosamine 4-epimerase activity http://purl.obolibrary.org/obo/GO_0003974 CHEBI:49049 biolink:ChemicalSubstance 3-oxo-3-ureidopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49049 CHEBI:50038 biolink:ChemicalSubstance deoxyhypusine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50038 GO:0003977 biolink:MolecularActivity UDP-N-acetylglucosamine diphosphorylase activity Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine. RHEA:13509|KEGG_REACTION:R00416|MetaCyc:NAG1P-URIDYLTRANS-RXN|Reactome:R-HSA-446204|EC:2.7.7.23 go-plus.json uridine diphosphoacetylglucosamine pyrophosphorylase activity|UDP-GlcNAc pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity|UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity|uridine diphosphoacetylglucosamine phosphorylase activity|N-acetylglucosamine-1-phosphate uridyltransferase activity|UDP-acetylglucosamine pyrophosphorylase activity|acetylglucosamine 1-phosphate uridylyltransferase|uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity|GlmU uridylyltransferase activity|UDP-N-acetylglucosamine pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0003977 CHEBI:50037 biolink:ChemicalSubstance N-benzoylanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50037 GO:0003976 biolink:MolecularActivity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose. EC:2.7.8.17|RHEA:13581|MetaCyc:2.7.8.17-RXN go-plus.json UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity|N-acetylglucosaminylphosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|N-acetylglucosaminyl phosphotransferase activity|lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0003976 CHEBI:50036 biolink:ChemicalSubstance (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan go-plus.json http://purl.obolibrary.org/obo/CHEBI_50036 chebi_ph7_3 GO:0003971 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003971 GO:0003973 biolink:MolecularActivity (S)-2-hydroxy-acid oxidase activity Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide. Reactome:R-HSA-389842|MetaCyc:RXN-969|EC:1.1.3.15|MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN|Reactome:R-HSA-6787811|RHEA:16789 go-plus.json glycolate oxidase activity|L-2-hydroxy acid oxidase|long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity|hydroxy-acid oxidase A activity|hydroxy-acid oxidase B activity|L-alpha-hydroxy acid oxidase|medium-chain-(S)-2-hydroxy-acid oxidase activity|very-long-chain-(S)-2-hydroxy-acid oxidase activity|hydroxyacid oxidase A http://purl.obolibrary.org/obo/GO_0003973 GO:1904539 biolink:BiologicalProcess negative regulation of glycolytic process through fructose-6-phosphate Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate. go-plus.json negative regulation of glycolysis through fructose-6-phosphate|down-regulation of glycolytic process through fructose-6-phosphate|down-regulation of glycolysis through fructose-6-phosphate|inhibition of glycolytic process through fructose-6-phosphate|inhibition of glycolysis through fructose-6-phosphate|down regulation of glycolysis through fructose-6-phosphate|down regulation of glycolytic process through fructose-6-phosphate|downregulation of glycolytic process through fructose-6-phosphate|downregulation of glycolysis through fructose-6-phosphate http://purl.obolibrary.org/obo/GO_1904539 GO:0003972 biolink:MolecularActivity RNA ligase (ATP) activity Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m). MetaCyc:RNA-LIGASE-ATP-RXN|EC:6.5.1.3|Reactome:R-HSA-5696816 go-plus.json poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)|ribonucleic ligase activity|polyribonucleotide ligase activity|polyribonucleotide synthase (ATP) activity http://purl.obolibrary.org/obo/GO_0003972 CL:0002603 biolink:Cell astrocyte of the cerebellum An astrocyte of the cerebellum. go-plus.json http://purl.obolibrary.org/obo/CL_0002603 GO:1904538 biolink:BiologicalProcess regulation of glycolytic process through fructose-6-phosphate Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate. go-plus.json regulation of glycolysis through fructose-6-phosphate http://purl.obolibrary.org/obo/GO_1904538 GO:1904537 biolink:BiologicalProcess negative regulation of mitotic telomere tethering at nuclear periphery Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery. go-plus.json downregulation of mitotic telomere tethering at nuclear periphery|down-regulation of mitotic telomere tethering at nuclear periphery|inhibition of mitotic telomere tethering at nuclear periphery|down regulation of mitotic telomere tethering at nuclear periphery http://purl.obolibrary.org/obo/GO_1904537 CL:0002605 biolink:Cell astrocyte of the cerebral cortex An astrocyte of the cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/CL_0002605 CHEBI:49044 biolink:ChemicalSubstance (-)-germacrene D go-plus.json http://purl.obolibrary.org/obo/CHEBI_49044 chebi_ph7_3 GO:1904536 biolink:BiologicalProcess regulation of mitotic telomere tethering at nuclear periphery Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery. go-plus.json http://purl.obolibrary.org/obo/GO_1904536 GO:1904535 biolink:BiologicalProcess positive regulation of telomeric loop disassembly Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly. go-plus.json upregulation of T loop disassembly|up regulation of telomeric loop disassembly|up-regulation of T loop disassembly|activation of T loop disassembly|upregulation of telomeric loop disassembly|positive regulation of T loop disassembly|up-regulation of telomeric loop disassembly|up regulation of T loop disassembly|activation of telomeric loop disassembly http://purl.obolibrary.org/obo/GO_1904535 CL:0002604 biolink:Cell astrocyte of the hippocampus go-plus.json http://purl.obolibrary.org/obo/CL_0002604 CHEBI:49043 biolink:ChemicalSubstance beta-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_49043 CHEBI:25072 biolink:ChemicalSubstance lombricine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25072 GO:1904534 biolink:BiologicalProcess negative regulation of telomeric loop disassembly Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly. go-plus.json inhibition of T loop disassembly|downregulation of telomeric loop disassembly|down regulation of telomeric loop disassembly|inhibition of telomeric loop disassembly|down-regulation of T loop disassembly|negative regulation of T loop disassembly|downregulation of T loop disassembly|down-regulation of telomeric loop disassembly|down regulation of T loop disassembly http://purl.obolibrary.org/obo/GO_1904534 CHEBI:49046 biolink:ChemicalSubstance (+)-germacrene D go-plus.json http://purl.obolibrary.org/obo/CHEBI_49046 chebi_ph7_3 CL:0002607 biolink:Cell migratory enteric neural crest cell A neural crest cell that gives rise to cells of the enteric nervous system. go-plus.json http://purl.obolibrary.org/obo/CL_0002607 CL:0002606 biolink:Cell astrocyte of the spinal cord An astrocyte of the spinal cord. go-plus.json http://purl.obolibrary.org/obo/CL_0002606 GO:1904533 biolink:BiologicalProcess regulation of telomeric loop disassembly Any process that modulates the frequency, rate or extent of telomeric loop disassembly. go-plus.json regulation of T loop disassembly http://purl.obolibrary.org/obo/GO_1904533 CHEBI:49045 biolink:ChemicalSubstance germacrene D go-plus.json http://purl.obolibrary.org/obo/CHEBI_49045 chebi_ph7_3 CHEBI:25078 biolink:ChemicalSubstance luciferin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25078 CL:0002609 biolink:Cell neuron of cerebral cortex A CNS neuron of the cerebral cortex. go-plus.json cortical neuron http://purl.obolibrary.org/obo/CL_0002609 GO:1904532 biolink:MolecularActivity obsolete ATP-dependent microtubule motor activity, minus-end-directed involved in microtubule-based movement OBSOLETE. Any ATP-dependent microtubule motor activity, minus-end-directed that is involved in microtubule-based movement. go-plus.json http://purl.obolibrary.org/obo/GO_1904532 GO:1904531 biolink:BiologicalProcess positive regulation of actin filament binding Any process that activates or increases the frequency, rate or extent of actin filament binding. go-plus.json positive regulation of actin cross-linking activity|upregulation of actin filament binding|up-regulation of F-actin binding|up regulation of actin cross-linking activity|up-regulation of actin filament binding|activation of actin filament binding|upregulation of F-actin binding|upregulation of actin cross-linking activity|up regulation of F-actin binding|up-regulation of actin cross-linking activity|up regulation of actin filament binding|activation of F-actin binding|positive regulation of F-actin binding|activation of actin cross-linking activity http://purl.obolibrary.org/obo/GO_1904531 CL:0002608 biolink:Cell hippocampal neuron A neuron of the hippocampus. go-plus.json http://purl.obolibrary.org/obo/CL_0002608 GO:1904541 biolink:BiologicalProcess fungal-type cell wall disassembly involved in conjugation with cellular fusion Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion. go-plus.json fungal-type cell wall disassembly involved in mating|fungal-type cell wall disassembly involved in cell fusion http://purl.obolibrary.org/obo/GO_1904541 GO:1904540 biolink:BiologicalProcess positive regulation of glycolytic process through fructose-6-phosphate Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate. go-plus.json upregulation of glycolytic process through fructose-6-phosphate|upregulation of glycolysis through fructose-6-phosphate|up regulation of glycolytic process through fructose-6-phosphate|up regulation of glycolysis through fructose-6-phosphate|activation of glycolysis through fructose-6-phosphate|activation of glycolytic process through fructose-6-phosphate|positive regulation of glycolysis through fructose-6-phosphate|up-regulation of glycolysis through fructose-6-phosphate|up-regulation of glycolytic process through fructose-6-phosphate http://purl.obolibrary.org/obo/GO_1904540 CHEBI:49051 biolink:ChemicalSubstance 5,7-dihydro-1H-purine-2,6,8(9H)-trione go-plus.json http://purl.obolibrary.org/obo/CHEBI_49051 chebi_ph7_3 CL:0002601 biolink:Cell uterine smooth muscle cell A smooth muscle cell of the uterus. go-plus.json http://purl.obolibrary.org/obo/CL_0002601 CHEBI:49050 biolink:ChemicalSubstance ureidoglycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49050 PR:000012059 biolink:Protein oncostatin-M A protein that is a translation product of the human OSM gene or a 1:1 ortholog thereof. go-plus.json OSM http://purl.obolibrary.org/obo/PR_000012059 CHEBI:50030 biolink:ChemicalSubstance thujene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50030 GO:0003979 biolink:MolecularActivity UDP-glucose 6-dehydrogenase activity Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate. EC:1.1.1.22|KEGG_REACTION:R00286|Reactome:R-HSA-173597|RHEA:23596|MetaCyc:UGD-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0003979 GO:0003978 biolink:MolecularActivity UDP-glucose 4-epimerase activity Catalysis of the reaction: UDP-glucose = UDP-galactose. Reactome:R-HSA-5610036|MetaCyc:UDPGLUCEPIM-RXN|RHEA:22168|EC:5.1.3.2|Reactome:R-HSA-70369 go-plus.json 4-epimerase activity|UDPgalactose 4-epimerase activity|uridine diphosphate galactose 4-epimerase activity|uridine diphospho-galactose-4-epimerase activity|uridine diphosphoglucose epimerase activity|UDP-D-galactose 4-epimerase activity|UDPglucose 4-epimerase activity|uridine diphosphate glucose 4-epimerase activity|uridine diphosphoglucose 4-epimerase activity|UDP-galactose 4-epimerase activity|UDPG-4-epimerase activity|galactowaldenase activity|UDP-glucose epimerase activity http://purl.obolibrary.org/obo/GO_0003978 CHEBI:50034 biolink:ChemicalSubstance phellandrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50034 CHEBI:49039 biolink:ChemicalSubstance 3-dehydro-L-gulonic acid 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49039 GO:0003986 biolink:MolecularActivity acetyl-CoA hydrolase activity Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+). MetaCyc:ACETYL-COA-HYDROLASE-RXN|Reactome:R-HSA-390304|EC:3.1.2.1|Reactome:R-HSA-2066779|KEGG_REACTION:R00227|RHEA:20289 go-plus.json acetyl coenzyme A hydrolase activity|acetyl-CoA thiol esterase activity|acetyl coenzyme A deacylase activity|acetyl coenzyme A acylase activity|acetyl-CoA deacylase activity|acetyl-CoA acylase activity http://purl.obolibrary.org/obo/GO_0003986 CHEBI:50028 biolink:ChemicalSubstance (-)-sabinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50028 chebi_ph7_3 GO:0003985 biolink:MolecularActivity acetyl-CoA C-acetyltransferase activity Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA. Reactome:R-HSA-8848215|Reactome:R-HSA-74181|Reactome:R-HSA-70844|MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN|UM-BBD_enzymeID:e0144|RHEA:21036|Reactome:R-HSA-73916|EC:2.3.1.9 go-plus.json 3-oxothiolase activity|acetyl-CoA acetyltransferase activity|thiolase II|acetyl-CoA:acetyl-CoA C-acetyltransferase activity|acetyl-CoA:N-acetyltransferase activity|acetoacetyl-CoA thiolase activity|acetyl coenzyme A thiolase activity|beta-acetoacetyl coenzyme A thiolase activity|2-methylacetoacetyl-CoA thiolase http://purl.obolibrary.org/obo/GO_0003985 CHEBI:50027 biolink:ChemicalSubstance sabinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50027 chebi_ph7_3 CHEBI:49038 biolink:ChemicalSubstance L-methionyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_49038 GO:0003988 biolink:MolecularActivity acetyl-CoA C-acyltransferase activity Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. UM-BBD_reactionID:r1051|Reactome:R-HSA-77271|Reactome:R-HSA-77304|Reactome:R-HSA-390250|EC:2.3.1.16|MetaCyc:KETOACYLCOATHIOL-RXN|Reactome:R-HSA-77329|Reactome:R-HSA-77309|Reactome:R-HSA-77340|Reactome:R-HSA-8874745|RHEA:21564|Reactome:R-HSA-77321 go-plus.json long-chain 3-oxoacyl-CoA thiolase activity|3-oxoacyl-coenzyme A thiolase activity|2-methylacetoacetyl-CoA thiolase|thiolase I|beta-ketoacyl-CoA thiolase activity|2-keto-acyl thiolase activity|3-ketoacyl CoA thiolase activity|3-ketothiolase activity|ketoacyl-coenzyme A thiolase activity|beta-ketothiolase activity|6-oxoacyl-CoA thiolase activity|pro-3-ketoacyl-CoA thiolase activity|3-ketoacyl-CoA thiolase activity|KAT|3-ketoacyl coenzyme A thiolase activity|3-oxoacyl-CoA thiolase activity|acyl-CoA:acetyl-CoA C-acyltransferase activity|beta-ketoacyl coenzyme A thiolase activity|acetoacetyl-CoA beta-ketothiolase activity|3-ketoacyl thiolase activity|acetyl-CoA acyltransferase activity|oxoacyl-coenzyme A thiolase activity|beta-ketoadipyl coenzyme A thiolase activity|beta-ketoadipyl-CoA thiolase activity|ketoacyl-CoA acyltransferase activity http://purl.obolibrary.org/obo/GO_0003988 CHEBI:50026 biolink:ChemicalSubstance (+)-beta-pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50026 chebi_ph7_3 GO:0003987 biolink:MolecularActivity acetate-CoA ligase activity Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. RHEA:23176|EC:6.2.1.1|Reactome:R-HSA-71735|Reactome:R-HSA-449911|Reactome:R-HSA-8875071|MetaCyc:ACETATE--COA-LIGASE-RXN go-plus.json acetyl CoA ligase activity|acetic thiokinase activity|short-chain acyl-coenzyme A synthetase activity|acetyl activating enzyme|acetyl-CoA synthetase activity|acetyl CoA synthase activity|acyl-activating enzyme activity|ACS|acetyl coenzyme A synthetase activity|acetyl-coenzyme A synthase activity|acetate thiokinase activity|short chain fatty acyl-CoA synthetase activity|acetate:CoA ligase (AMP-forming)|acetyl-activating enzyme activity|acetate to acetyl-CoA|acetyl-CoA synthase activity http://purl.obolibrary.org/obo/GO_0003987 CHEBI:50025 biolink:ChemicalSubstance beta-pinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50025 chebi_ph7_3 GO:0003982 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003982 GO:0003981 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003981 GO:0003984 biolink:MolecularActivity acetolactate synthase activity Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2. EC:2.2.1.6|MetaCyc:ACETOLACTSYN-RXN|RHEA:25249 go-plus.json alpha-acetohydroxyacid synthase activity|alpha-acetolactate synthase activity|acetohydroxy acid synthetase activity|acetolactate pyruvate-lyase (carboxylating) activity|acetohydroxyacid synthase activity|acetolactic synthetase activity|alpha-acetolactate synthetase activity|alpha-acetohydroxy acid synthetase activity|pyruvate:pyruvate acetaldehydetransferase (decarboxylating) http://purl.obolibrary.org/obo/GO_0003984 GO:0003983 biolink:MolecularActivity UTP:glucose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose. Reactome:R-HSA-70286|MetaCyc:GLUC1PURIDYLTRANS-RXN|EC:2.7.7.9|KEGG_REACTION:R00289|RHEA:19889 go-plus.json UDP-glucose pyrophosphorylase activity|uridine-diphosphate glucose pyrophosphorylase activity|UDP-glucose diphosphorylase activity|UDPG pyrophosphorylase activity|UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity|glucose-1-phosphate uridylyltransferase activity|UDPG phosphorylase activity|UTP-glucose-1-phosphate uridylyltransferase activity|UDP glucose pyrophosphorylase activity|uridine diphosphoglucose pyrophosphorylase activity|uridine diphosphate-D-glucose pyrophosphorylase activity|uridine 5'-diphosphoglucose pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0003983 CHEBI:50029 biolink:ChemicalSubstance (+)-sabinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50029 chebi_ph7_3 CHEBI:49031 biolink:ChemicalSubstance L-methionine (S)-S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49031 CL:0002614 biolink:Cell neuron of the substantia nigra A neuron of the substantia nigra. go-plus.json http://purl.obolibrary.org/obo/CL_0002614 CL:0002613 biolink:Cell striatum neuron A neuron of the striatum. go-plus.json http://purl.obolibrary.org/obo/CL_0002613 CHEBI:49030 biolink:ChemicalSubstance (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49030 GO:1904547 biolink:BiologicalProcess regulation of cellular response to glucose starvation Any process that modulates the frequency, rate or extent of cellular response to glucose starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1904547 GO:0003980 biolink:MolecularActivity UDP-glucose:glycoprotein glucosyltransferase activity Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins. Reactome:R-HSA-548884 go-plus.json UGGT activity http://purl.obolibrary.org/obo/GO_0003980 CHEBI:49033 biolink:ChemicalSubstance methionine S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49033 GO:1904546 biolink:BiologicalProcess obsolete negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway OBSOLETE. Any negative regulation of cAMP-dependent protein kinase activity that is involved in negative regulation of glucose mediated signaling pathway. go-plus.json negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of PKA C involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA C involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of STK22 involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in down regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in inhibition of glucose mediated signalling|negative regulation of PKA involved in down-regulation of glucose mediated signalling|negative regulation of PKA involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of AMPK involved in downregulation of glucose mediated signaling pathway|negative regulation of AMPK involved in inhibition of glucose mediated signalling|negative regulation of PKA C involved in down-regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signalling|negative regulation of PKA C involved in negative regulation of glucose mediated signalling|negative regulation of STK22 involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of PKA C involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signalling|negative regulation of PKA C involved in downregulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in downregulation of glucose mediated signalling|negative regulation of STK22 involved in down-regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in negative regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in inhibition of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down-regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of AMPK involved in downregulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signaling pathway|negative regulation of PKA involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA involved in negative regulation of glucose mediated signaling pathway http://purl.obolibrary.org/obo/GO_1904546 CHEBI:49032 biolink:ChemicalSubstance L-methionine (R)-S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49032 CHEBI:49035 biolink:ChemicalSubstance D-methionine (R)-S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49035 GO:1904544 biolink:BiologicalProcess positive regulation of free ubiquitin chain polymerization Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization. go-plus.json up regulation of free ubiquitin chain polymerization|activation of free ubiquitin chain polymerization|up-regulation of free ubiquitin chain polymerization|upregulation of free ubiquitin chain polymerization http://purl.obolibrary.org/obo/GO_1904544 CHEBI:49034 biolink:ChemicalSubstance D-methionine S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49034 GO:1904543 biolink:BiologicalProcess negative regulation of free ubiquitin chain polymerization Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization. go-plus.json down-regulation of free ubiquitin chain polymerization|inhibition of free ubiquitin chain polymerization|down regulation of free ubiquitin chain polymerization|downregulation of free ubiquitin chain polymerization http://purl.obolibrary.org/obo/GO_1904543 GO:1904542 biolink:BiologicalProcess regulation of free ubiquitin chain polymerization Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization. go-plus.json http://purl.obolibrary.org/obo/GO_1904542 CHEBI:49036 biolink:ChemicalSubstance D-methionine (S)-S-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_49036 GO:1904552 biolink:BiologicalProcess regulation of chemotaxis to arachidonic acid Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1904552 GO:1904551 biolink:BiologicalProcess cellular response to arachidonic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904551 GO:1904550 biolink:BiologicalProcess response to arachidonic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904550 CHEBI:25091 biolink:ChemicalSubstance luteolin O-glucuronoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_25091 CL:0002612 biolink:Cell neuron of the ventral spinal cord A neuron of the ventral spinal cord. go-plus.json http://purl.obolibrary.org/obo/CL_0002612 CL:0002611 biolink:Cell neuron of the dorsal spinal cord A CNS neuron of the dorsal spinal cord. go-plus.json http://purl.obolibrary.org/obo/CL_0002611 GO:0003989 biolink:MolecularActivity acetyl-CoA carboxylase activity Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. EC:6.4.1.2|MetaCyc:ACETYL-COA-CARBOXYLTRANSFER-RXN|Reactome:R-HSA-200555|RHEA:11308|Reactome:R-HSA-8876889|Reactome:R-HSA-75851 go-plus.json acetyl coenzyme A carboxylase activity|acetyl-CoA:carbon-dioxide ligase (ADP-forming) http://purl.obolibrary.org/obo/GO_0003989 CHEBI:64669 biolink:ChemicalSubstance 2-hydroxy-3-methylbutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64669 chebi_ph7_3 CHEBI:64668 biolink:ChemicalSubstance geranylgeranyl-chlorophyll a go-plus.json http://purl.obolibrary.org/obo/CHEBI_64668 CL:1000050 biolink:Cell lateral line nerve glial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000050 NCBITaxon:1131492 biolink:OrganismalEntity Aspergillaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1131492 CHEBI:64672 biolink:ChemicalSubstance differentiation-inducing factor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64672 CHEBI:64670 biolink:ChemicalSubstance EC 1.8.1.9 (thioredoxin reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64670 CHEBI:64676 biolink:ChemicalSubstance CDP-N,N-dimethylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64676 CHEBI:64675 biolink:ChemicalSubstance 2,6-dioxo-6-phenylhexa-3-enoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64675 chebi_ph7_3 CHEBI:64674 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64674 CHEBI:64673 biolink:ChemicalSubstance fumigaclavine C go-plus.json http://purl.obolibrary.org/obo/CHEBI_64673 CHEBI:64678 biolink:ChemicalSubstance anthracycline cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_64678 CHEBI:64677 biolink:ChemicalSubstance daunorubicin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64677 chebi_ph7_3 CL:1000042 biolink:Cell forebrain neuroblast go-plus.json http://purl.obolibrary.org/obo/CL_1000042 CHEBI:74006 biolink:ChemicalSubstance 1-archaetidyl-1D-myo-inositol 3-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74006 chebi_ph7_3 CHEBI:74005 biolink:ChemicalSubstance 8-desmethylnovobiocic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_74005 CHEBI:74008 biolink:ChemicalSubstance 3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74008 chebi_ph7_3 GO:0052902 biolink:MolecularActivity spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine. EC:1.5.3.17|EC:1.5.3.13|KEGG_REACTION:R09077|MetaCyc:RXN-10461|MetaCyc:RXN-12089|RHEA:25808 go-plus.json N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity http://purl.obolibrary.org/obo/GO_0052902 GO:0052901 biolink:MolecularActivity spermine:oxygen oxidoreductase (spermidine-forming) activity Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine. EC:1.5.3.17|EC:1.5.3.16|MetaCyc:RXN-9015|RHEA:25804|EC:1.5.3.13|Reactome:R-HSA-141341|MetaCyc:1.5.3.17-RXN|KEGG_REACTION:R09076 go-plus.json N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity|spermine oxidase activity http://purl.obolibrary.org/obo/GO_0052901 CHEBI:74009 biolink:ChemicalSubstance 3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74009 chebi_ph7_3 GO:0052900 biolink:MolecularActivity spermine oxidase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal. EC:1.5.3.14|RHEA:25824|MetaCyc:RXN-6421 go-plus.json polyamine oxidase (propane-1,3-diamine-forming) activity http://purl.obolibrary.org/obo/GO_0052900 GO:0052906 biolink:MolecularActivity tRNA (guanine(37)-N(1))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine. RHEA:36899|EC:2.1.1.228|MetaCyc:RXN-12458 go-plus.json tRNA-(N(1)G37) methyltransferase activity|transfer RNA (m(1)G(37)) methyltransferase activity|tRNA (m(1)G(37)) methyltransferase activity http://purl.obolibrary.org/obo/GO_0052906 CHEBI:64683 biolink:ChemicalSubstance 1-acyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64683 chebi_ph7_3 GO:0052905 biolink:MolecularActivity tRNA (guanine(9)-N(1))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine. RHEA:43156|MetaCyc:RXN-12459|EC:2.1.1.221 go-plus.json tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity|tRNA (guanine-N(1)-)-methyltransferase activity|tRNA m(1)G(9)-methyltransferase activity|tRNA m(1)G(9) Mtase activity|tRNA(m(1)G(9)/m(1)A(9))Mtase activity http://purl.obolibrary.org/obo/GO_0052905 CHEBI:15709 biolink:ChemicalSubstance xanthotoxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15709 chebi_ph7_3 GO:0052904 biolink:MolecularActivity N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine. EC:1.5.3.17|MetaCyc:RXN-12091|EC:1.5.3.13|RHEA:25812|KEGG_REACTION:R09074|Reactome:R-HSA-141348|Reactome:R-HSA-141351|MetaCyc:RXN-9942 go-plus.json N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity http://purl.obolibrary.org/obo/GO_0052904 GO:0052903 biolink:MolecularActivity N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine. MetaCyc:RXN-9940|EC:1.5.3.17|EC:1.5.3.13|MetaCyc:RXN-12090|KEGG_REACTION:R03899|RHEA:25800 go-plus.json N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity http://purl.obolibrary.org/obo/GO_0052903 CHEBI:64687 biolink:ChemicalSubstance 2,6-dioxo-6-phenylhexa-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64687 CHEBI:15705 biolink:ChemicalSubstance L-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15705 GO:0052909 biolink:MolecularActivity 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA. RHEA:42780|MetaCyc:RXN-11634|EC:2.1.1.183 go-plus.json M(6)(2)A dimethylase activity http://purl.obolibrary.org/obo/GO_0052909 CHEBI:64686 biolink:ChemicalSubstance 7-formamidino-7-deazaguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64686 GO:0052908 biolink:MolecularActivity 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA. RHEA:19609|MetaCyc:RXN-11633|EC:2.1.1.182 go-plus.json S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase activity http://purl.obolibrary.org/obo/GO_0052908 CHEBI:15708 biolink:ChemicalSubstance trans-aconitate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15708 chebi_ph7_3 GO:0052907 biolink:MolecularActivity 23S rRNA (adenine(1618)-N(6))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA. RHEA:16497|KEGG_REACTION:R07232|MetaCyc:RXN-11596|EC:2.1.1.181 go-plus.json M(6)A(1618) activity|rRNA large subunit methyltransferase F activity http://purl.obolibrary.org/obo/GO_0052907 CHEBI:64684 biolink:ChemicalSubstance 7-formamidino-7-deazaguanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64684 chebi_ph7_3 CHEBI:15707 biolink:ChemicalSubstance 2,6-dioxo-6-phenylhexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15707 CHEBI:15702 biolink:ChemicalSubstance terephthalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15702 CHEBI:15704 biolink:ChemicalSubstance 6-alkylamino-7-beta-D-glucosylpurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15704 chebi_ph7_3 CHEBI:64689 biolink:ChemicalSubstance mycophenolic acid O-acyl-glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64689 CHEBI:15703 biolink:ChemicalSubstance alpha-maltose 6'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15703 CHEBI:64688 biolink:ChemicalSubstance artemisinic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_64688 chebi_ph7_3 CHEBI:15700 biolink:ChemicalSubstance dTDP-alpha-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15700 CL:1000073 biolink:Cell spinal cord radial glial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000073 CHEBI:74000 biolink:ChemicalSubstance 1-palmitoyl-2-palmitoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74000 chebi_ph7_3 CHEBI:74001 biolink:ChemicalSubstance 1-O-octadecyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74001 chebi_ph7_3 CHEBI:74004 biolink:ChemicalSubstance CDP-2,3-bis-O-(phytanyl)-sn-glycerol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74004 chebi_ph7_3 GO:0052913 biolink:MolecularActivity 16S rRNA (guanine(966)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine. EC:2.1.1.171|MetaCyc:RXN0-6515|RHEA:23548|KEGG_REACTION:R07234 go-plus.json http://purl.obolibrary.org/obo/GO_0052913 GO:0052912 biolink:MolecularActivity 23S rRNA (guanine(748)-N(1))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine. EC:2.1.1.188|MetaCyc:RXN-11599|RHEA:42904|KEGG_REACTION:R07233 go-plus.json 23S rRNA m(1)G(748) methyltransferase activity http://purl.obolibrary.org/obo/GO_0052912 GO:0052911 biolink:MolecularActivity 23S rRNA (guanine(745)-N(1))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine. EC:2.1.1.187|MetaCyc:RXN-11573|RHEA:42900|KEGG_REACTION:R07233 go-plus.json ribosomal ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|rlmA(I) methyltransferase activity|ribosomal RNA(m(1)G)-methylase activity|23S rRNA m(1)G(745) methyltransferase activity|rRNA(m(1)G)methylase activity http://purl.obolibrary.org/obo/GO_0052911 GO:0052910 biolink:MolecularActivity 23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA. MetaCyc:RXN-11597|EC:2.1.1.184|RHEA:42784 go-plus.json rRNA methyltransferase ermC' activity|ermC 23S rRNA methyltransferase activity|rRNA:m(6)A methyltransferase ermC' activity http://purl.obolibrary.org/obo/GO_0052910 GO:0052917 biolink:MolecularActivity dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol. KEGG_REACTION:R06260|EC:2.4.1.260|MetaCyc:RXN-5468|RHEA:29535 go-plus.json dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|dolichyl-P-mannose:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase activity|dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0052917 CHEBI:64694 biolink:ChemicalSubstance 3,4-dihydroxy-5-polyprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64694 chebi_ph7_3 GO:0052916 biolink:MolecularActivity 23S rRNA (guanine(1835)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine. MetaCyc:RXN-11635|EC:2.1.1.174|RHEA:42744|KEGG_REACTION:R07234 go-plus.json http://purl.obolibrary.org/obo/GO_0052916 CHEBI:64693 biolink:ChemicalSubstance (3R)-3-methyl-D-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64693 GO:0052915 biolink:MolecularActivity 23S rRNA (guanine(2445)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine. EC:2.1.1.173|MetaCyc:RXN-11574|RHEA:42740|KEGG_REACTION:R07234 go-plus.json http://purl.obolibrary.org/obo/GO_0052915 CHEBI:64692 biolink:ChemicalSubstance N(6)-[(3R)-3-methyl-D-ornithyl]-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64692 GO:0052914 biolink:MolecularActivity 16S rRNA (guanine(1207)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine. MetaCyc:RXN-11576|EC:2.1.1.172|RHEA:42736|KEGG_REACTION:R07234 go-plus.json M(2)G1207 methyltransferase activity http://purl.obolibrary.org/obo/GO_0052914 CHEBI:64691 biolink:ChemicalSubstance (11R)-dihydroartemisinic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_64691 chebi_ph7_3 CHEBI:64697 biolink:ChemicalSubstance acyl-CoA:cholesterol acyltransferase 2 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64697 GO:0052919 biolink:MolecularActivity aliphatic (R)-hydroxynitrile lyase activity Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide. EC:4.1.2.46 go-plus.json (R)-hydroxynitrile lyase activity|(R)-oxynitrilase activity|(R)-HNL activity http://purl.obolibrary.org/obo/GO_0052919 CHEBI:64696 biolink:ChemicalSubstance EC 2.3.1.26 (sterol O-acyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64696 GO:0052918 biolink:MolecularActivity dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. KEGG_REACTION:R06261|EC:2.4.1.261|MetaCyc:RXN-5469|RHEA:29539 go-plus.json http://purl.obolibrary.org/obo/GO_0052918 CHEBI:64695 biolink:ChemicalSubstance pyripyropene A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64695 chebi_ph7_3 CHEBI:74011 biolink:ChemicalSubstance (11Z)-3-oxoicosa-11-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74011 chebi_ph7_3 CHEBI:74010 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74010 chebi_ph7_3 CHEBI:74012 biolink:ChemicalSubstance (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74012 chebi_ph7_3 GO:0052920 biolink:MolecularActivity (2R)-2-hydroxy-2-methylbutanenitrile lyase activity Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide. KEGG_REACTION:R09358|MetaCyc:RXN-11733|RHEA:28170|EC:4.1.2.46 go-plus.json http://purl.obolibrary.org/obo/GO_0052920 CHEBI:74028 biolink:ChemicalSubstance beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74028 GO:0052924 biolink:MolecularActivity all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate. EC:2.5.1.85|RHEA:27594|KEGG_REACTION:R09251|MetaCyc:RXN-11486 go-plus.json solanesyl diphosphate synthase activity|nonaprenyl diphosphate synthase activity|solanesyl diphosphate synthetase activity http://purl.obolibrary.org/obo/GO_0052924 GO:0052923 biolink:MolecularActivity all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate. EC:2.5.1.84|RHEA:27563|KEGG_REACTION:R09250|MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN go-plus.json SPP synthase activity|solPP synthase activity|nonaprenyl diphosphate synthase activity|solanesyl-diphosphate synthase activity|SPP-synthase activity|solanesyl diphosphate synthetase activity http://purl.obolibrary.org/obo/GO_0052923 GO:0052922 biolink:MolecularActivity hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate. RHEA:27555|EC:2.5.1.82|KEGG_REACTION:R09246|MetaCyc:RXN-11485 go-plus.json hexaprenyl pyrophosphate synthetase activity|(all-trans)-hexaprenyl-diphosphate synthase activity|(all-E) hexaprenyl diphosphate synthase activity|hexaprenyl diphosphate synthase activity http://purl.obolibrary.org/obo/GO_0052922 GO:0052921 biolink:MolecularActivity acetone-cyanohydrin acetone-lyase (cyanide-forming) activity Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone. KEGG_REACTION:R01553|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN|EC:4.1.2.46|RHEA:11932 go-plus.json http://purl.obolibrary.org/obo/GO_0052921 GO:0052928 biolink:MolecularActivity CTP:3'-cytidine-tRNA cytidylyltransferase activity Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate. EC:2.7.7.72|KEGG_REACTION:R09384 go-plus.json http://purl.obolibrary.org/obo/GO_0052928 GO:0052927 biolink:MolecularActivity CTP:tRNA cytidylyltransferase activity Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate. EC:2.7.7.72|KEGG_REACTION:R09383 go-plus.json http://purl.obolibrary.org/obo/GO_0052927 GO:0052926 biolink:MolecularActivity dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. KEGG_REACTION:R06259|EC:2.4.1.259|RHEA:29531|MetaCyc:RXN-5467 go-plus.json dolichylphosphomannose-dependent ALG9 mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0052926 GO:0052925 biolink:MolecularActivity dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. RHEA:29527|KEGG_REACTION:R06258|EC:2.4.1.258|MetaCyc:RXN-5466 go-plus.json man(5)GlcNAc(2)-PP-Dol mannosyltransferase activity|dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0052925 GO:0052929 biolink:MolecularActivity ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate. RHEA:60012|KEGG_REACTION:R09386|EC:2.7.7.72 go-plus.json ATP:tRNA adenylyltransferase activity|ATP:3'-CC-tRNA adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0052929 CHEBI:74020 biolink:ChemicalSubstance diosgenin 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_74020 chebi_ph7_3 NCBITaxon:37414 biolink:OrganismalEntity Physcomitrium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_37414 CHEBI:74023 biolink:ChemicalSubstance dioscin go-plus.json http://purl.obolibrary.org/obo/CHEBI_74023 chebi_ph7_3 CHEBI:74026 biolink:ChemicalSubstance 26-desglucoprotodioscin go-plus.json http://purl.obolibrary.org/obo/CHEBI_74026 chebi_ph7_3 GO:0052931 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052931 CHEBI:74038 biolink:ChemicalSubstance beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74038 GO:0052930 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052930 GO:0052935 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052935 GO:0052934 biolink:MolecularActivity alcohol dehydrogenase (cytochrome c) activity Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+. MetaCyc:RXN-11333|UM-BBD_enzymeID:e0004|RHEA:51020|EC:1.1.2.8|KEGG_REACTION:R05198|KEGG_REACTION:R05285 go-plus.json alcohol:(acceptor) oxidoreductase activity|alcohol:cytochrome c oxidoreductase activity|alcohol:acceptor oxidoreductase activity|alcohol dehydrogenase (acceptor) activity|PQQ-dependent alcohol dehydrogenase activity|quinoprotein alcohol dehydrogenase activity|ethanol:cytochrome c oxidoreductase activity|2-chloroethanol:cytochrome c oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052934 UBERON:4000170 biolink:AnatomicalEntity median fin skeleton Postcranial axial skeleton that is unpaired and located on the sagittal plane of the organism. go-plus.json unpaired fin skeleton|axial fin skeleton http://purl.obolibrary.org/obo/UBERON_4000170 GO:0052933 biolink:MolecularActivity alcohol dehydrogenase (cytochrome c(L)) activity Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+. MetaCyc:RXN-11332|MetaCyc:RXN-2861|RHEA:51004|KEGG_REACTION:R01146|KEGG_REACTION:R09128|KEGG_REACTION:R09127|EC:1.1.2.7 go-plus.json 2-chloroethanol cytochrome-c oxidoreductase activity|ethanol cytochrome-c oxidoreductase activity|methanol dehydrogenase activity|alcohol:cytochrome c(L) oxidoreductase activity|methanol ferricytochrome-c oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052933 GO:0052932 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052932 GO:0052936 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052936 CL:1000001 biolink:Cell retrotrapezoid nucleus neuron go-plus.json http://purl.obolibrary.org/obo/CL_1000001 CHEBI:74030 biolink:ChemicalSubstance 3'-N-debenzoyl-2'-deoxytaxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74030 CHEBI:74033 biolink:ChemicalSubstance beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74033 CHEBI:74032 biolink:ChemicalSubstance beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74032 UBERON:4000168 biolink:AnatomicalEntity dorsal fin skeleton Median fin skeleton located on the dorsal surface of the organism. go-plus.json http://purl.obolibrary.org/obo/UBERON_4000168 CHEBI:74035 biolink:ChemicalSubstance small nuclear RNA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74035 UBERON:4000167 biolink:AnatomicalEntity caudal fin skeleton Median fin skeleton supporting the caudal fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_4000167 CHEBI:74034 biolink:ChemicalSubstance alpha-linolenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74034 chebi_ph7_3 CHEBI:74037 biolink:ChemicalSubstance (11Z)-3-oxoicosa-11-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74037 CHEBI:74036 biolink:ChemicalSubstance alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74036 UBERON:4000164 biolink:AnatomicalEntity caudal fin The caudal fin is the most posterior median fin. It is composed of a complex of modified centra and modified neural and hemal arches and spines. go-plus.json nageoire caudale|tail|uroptérygie|uroptère|tail fin http://purl.obolibrary.org/obo/UBERON_4000164 UBERON:4000163 biolink:AnatomicalEntity anal fin Median fin that is located posterior to the anus. go-plus.json nageoire anale|proctoptérygie|proctoptère http://purl.obolibrary.org/obo/UBERON_4000163 UBERON:4000166 biolink:AnatomicalEntity anal fin skeleton Median fin skeleton that is located posterior to the anus. go-plus.json http://purl.obolibrary.org/obo/UBERON_4000166 UBERON:4000162 biolink:AnatomicalEntity median fin Fin that is an unpaired fin located in the sagittal plane of the organism. go-plus.json nageoire impaire|périssoptérygie http://purl.obolibrary.org/obo/UBERON_4000162 CHEBI:156473 biolink:ChemicalSubstance cyclobutanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_156473 CHEBI:74040 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74040 CHEBI:74042 biolink:ChemicalSubstance 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74042 chebi_ph7_3 CHEBI:74041 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74041 CHEBI:74043 biolink:ChemicalSubstance 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74043 CHEBI:74045 biolink:ChemicalSubstance GDP-4-amino-4,6-dideoxy-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_74045 CL:0002681 biolink:Cell kidney cortical cell go-plus.json http://purl.obolibrary.org/obo/CL_0002681 CL:0002680 biolink:Cell PP cell of intestine A PP cell found in intestine. go-plus.json http://purl.obolibrary.org/obo/CL_0002680 CHEBI:74047 biolink:ChemicalSubstance GDP-N-acetyl-alpha-D-perosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74047 CL:0012001 biolink:Cell neuron of the forebrain A CNS neuron of the forebrain. go-plus.json forebrain neuron http://purl.obolibrary.org/obo/CL_0012001 CL:0012000 biolink:Cell astrocyte of the forebrain An astrocyte of the forebrain. go-plus.json forebrain astrocyte http://purl.obolibrary.org/obo/CL_0012000 CHEBI:156461 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_156461 chebi_ph7_3 CL:1000022 biolink:Cell mesonephric nephron tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000022 CHEBI:74050 biolink:ChemicalSubstance CDP-2,3-bis-O-(phytanyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74050 CHEBI:74054 biolink:ChemicalSubstance (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74054 chebi_ph7_3 UBERON:0036654 biolink:AnatomicalEntity wall of lateral ventricle go-plus.json http://purl.obolibrary.org/obo/UBERON_0036654 UBERON:0036657 biolink:AnatomicalEntity wall of fourth ventricle go-plus.json http://purl.obolibrary.org/obo/UBERON_0036657 UBERON:0036656 biolink:AnatomicalEntity wall of third ventricle go-plus.json http://purl.obolibrary.org/obo/UBERON_0036656 CHEBI:15647 biolink:ChemicalSubstance leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15647 CHEBI:15646 biolink:ChemicalSubstance 20-hydroxy-leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15646 CHEBI:15649 biolink:ChemicalSubstance 3,6,9-trihydroxypterocarpan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15649 chebi_ph7_3 CHEBI:15648 biolink:ChemicalSubstance (6aR,11aR)-3,9-dihydroxypterocarpan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15648 chebi_ph7_3 CHEBI:15642 biolink:ChemicalSubstance 4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15642 chebi_ph7_3 CHEBI:15645 biolink:ChemicalSubstance (6S)-6-hydroxyhyoscyamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15645 CHEBI:40611 biolink:ChemicalSubstance adamantanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_40611 chebi_ph7_3 CHEBI:15644 biolink:ChemicalSubstance (S)-NADHX(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15644 CHEBI:15641 biolink:ChemicalSubstance 5-methyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15641 CHEBI:15640 biolink:ChemicalSubstance 5-formyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15640 UBERON:0036661 biolink:AnatomicalEntity wall of ventricular system of brain go-plus.json http://purl.obolibrary.org/obo/UBERON_0036661 CHEBI:15639 biolink:ChemicalSubstance 5-formimidoyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15639 CHEBI:15636 biolink:ChemicalSubstance (6R)-5,10-methylenetetrahydrofolate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15636 chebi_ph7_3 UBERON:0036658 biolink:AnatomicalEntity wall of central canal of spinal cord go-plus.json wall of central canal http://purl.obolibrary.org/obo/UBERON_0036658 CHEBI:15635 biolink:ChemicalSubstance (6S)-5,6,7,8-tetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15635 CHEBI:15638 biolink:ChemicalSubstance (6R)-5,10-methenyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15638 CHEBI:15637 biolink:ChemicalSubstance 10-formyltetrahydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15637 CHEBI:15632 biolink:ChemicalSubstance 5(S)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15632 CHEBI:15631 biolink:ChemicalSubstance (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15631 CHEBI:15634 biolink:ChemicalSubstance 10-formyldihydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15634 CHEBI:15633 biolink:ChemicalSubstance dihydrofolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15633 CHEBI:15630 biolink:ChemicalSubstance (5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15630 NCBITaxon:3700 biolink:OrganismalEntity Brassicaceae go-plus.json mustard family|Cruciferae http://purl.obolibrary.org/obo/NCBITaxon_3700 NCBITaxon:3702 biolink:OrganismalEntity Arabidopsis thaliana go-plus.json thale cress|thale-cress|mouse-ear cress http://purl.obolibrary.org/obo/NCBITaxon_3702 NCBITaxon:3701 biolink:OrganismalEntity Arabidopsis go-plus.json Cardaminopsis http://purl.obolibrary.org/obo/NCBITaxon_3701 NCBITaxon:3708 biolink:OrganismalEntity Brassica napus go-plus.json rape|oilseed rape|rapeseeds http://purl.obolibrary.org/obo/NCBITaxon_3708 NCBITaxon:3705 biolink:OrganismalEntity Brassica go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3705 CHEBI:15669 biolink:ChemicalSubstance trans-cinnamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15669 chebi_ph7_3 CHEBI:64603 biolink:ChemicalSubstance diadenosyl polyphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64603 CHEBI:15668 biolink:ChemicalSubstance (1E)-4-oxobut-1-ene-1,2,4-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15668 CHEBI:64602 biolink:ChemicalSubstance dermatan sulfate proteoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_64602 CHEBI:64600 biolink:ChemicalSubstance C21-steroid hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64600 CHEBI:15665 biolink:ChemicalSubstance (4-hydroxyphenyl)acetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_15665 chebi_ph7_3 CHEBI:64607 biolink:ChemicalSubstance Fe4S4 iron-sulfur cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_64607 CHEBI:64606 biolink:ChemicalSubstance Fe3S4 iron-sulfur cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_64606 CHEBI:15664 biolink:ChemicalSubstance (2E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15664 CHEBI:15667 biolink:ChemicalSubstance (Z)-(4-hydroxyphenyl)acetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_15667 chebi_ph7_3 CHEBI:64604 biolink:ChemicalSubstance diphosphoinositol polyphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64604 CHEBI:15666 biolink:ChemicalSubstance (E)-(4-hydroxyphenyl)acetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_15666 chebi_ph7_3 CHEBI:543745 biolink:ChemicalSubstance 3',4',5'-O-trimethyltricetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_543745 CHEBI:15661 biolink:ChemicalSubstance (2E)-2-(methoxycarbonylmethyl)but-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15661 CHEBI:15660 biolink:ChemicalSubstance (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15660 chebi_ph7_3 CHEBI:64609 biolink:ChemicalSubstance dinitrosyl-iron complex go-plus.json http://purl.obolibrary.org/obo/CHEBI_64609 CHEBI:15663 biolink:ChemicalSubstance (2E)-3-(methoxycarbonyl)pent-2-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15663 CHEBI:15662 biolink:ChemicalSubstance (2E)-2,6-dimethylocta-2,7-diene-1,6-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15662 chebi_ph7_3 CHEBI:64608 biolink:ChemicalSubstance GDP-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_64608 NCBITaxon:3711 biolink:OrganismalEntity Brassica rapa go-plus.json field mustard http://purl.obolibrary.org/obo/NCBITaxon_3711 UBERON:0012651 biolink:AnatomicalEntity mucosa of gastroduodenal junction A mucosa that is part of a gastroduodenal junction. go-plus.json gastroduodenal mucosa http://purl.obolibrary.org/obo/UBERON_0012651 UBERON:0012650 biolink:AnatomicalEntity gastroduodenal junction A anatomical junction that connects a stomach and connects a duodenum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012650 CHEBI:64610 biolink:ChemicalSubstance tenocyclidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64610 CHEBI:15658 biolink:ChemicalSubstance 7(S),8(S)-DiHODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15658 CHEBI:15657 biolink:ChemicalSubstance (11S)-11-hydroperoxylinoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15657 CHEBI:64612 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64612 chebi_ph7_3 CHEBI:15659 biolink:ChemicalSubstance (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15659 chebi_ph7_3 CHEBI:64611 biolink:ChemicalSubstance ether lipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64611 CHEBI:64618 biolink:ChemicalSubstance phosphagen go-plus.json http://purl.obolibrary.org/obo/CHEBI_64618 CHEBI:15653 biolink:ChemicalSubstance (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15653 CHEBI:64616 biolink:ChemicalSubstance apiogalacturonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_64616 CHEBI:64615 biolink:ChemicalSubstance triacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64615 chebi_ph7_3 CHEBI:15655 biolink:ChemicalSubstance 13(S)-HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15655 CHEBI:15650 biolink:ChemicalSubstance leukotriene E4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15650 NCBITaxon:1924738 biolink:OrganismalEntity Craspedida go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1924738 CHEBI:15652 biolink:ChemicalSubstance 5'-xanthylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15652 CHEBI:15651 biolink:ChemicalSubstance leukotriene A4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15651 CHEBI:15607 biolink:ChemicalSubstance (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15607 CHEBI:64621 biolink:ChemicalSubstance quercetin O-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_64621 CHEBI:15606 biolink:ChemicalSubstance (2S)-flavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15606 chebi_ph7_3 CHEBI:64620 biolink:ChemicalSubstance purine ribonucleoside bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64620 CHEBI:15609 biolink:ChemicalSubstance N-(aminomethyl)urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_15609 CHEBI:15608 biolink:ChemicalSubstance (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15608 CHEBI:15603 biolink:ChemicalSubstance L-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15603 CHEBI:15602 biolink:ChemicalSubstance (2S)-2-[(R)-1-carboxyethylamino]pentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15602 CHEBI:64624 biolink:ChemicalSubstance microcin B17 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64624 CHEBI:15605 biolink:ChemicalSubstance (2S)-flavan-4-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15605 chebi_ph7_3 CHEBI:64623 biolink:ChemicalSubstance saturated monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64623 CHEBI:64622 biolink:ChemicalSubstance reuteran go-plus.json http://purl.obolibrary.org/obo/CHEBI_64622 CHEBI:15604 biolink:ChemicalSubstance (3R)-beta-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15604 CHEBI:64629 biolink:ChemicalSubstance 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64629 CHEBI:64628 biolink:ChemicalSubstance somatostatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64628 CHEBI:15601 biolink:ChemicalSubstance (2R,4S)-2,4-diaminopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15601 CHEBI:64627 biolink:ChemicalSubstance microcin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64627 CHEBI:64626 biolink:ChemicalSubstance teichuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64626 CHEBI:15600 biolink:ChemicalSubstance (+)-catechin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15600 chebi_ph7_3 CHEBI:64632 biolink:ChemicalSubstance indoleacetic acid amide conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64632 CHEBI:64631 biolink:ChemicalSubstance indoleacetic acid conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64631 CHEBI:64634 biolink:ChemicalSubstance kaempferol O-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_64634 CHEBI:64633 biolink:ChemicalSubstance indoleacetic acid ester conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64633 CHEBI:64637 biolink:ChemicalSubstance O-polysaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64637 NCBITaxon:3744 biolink:OrganismalEntity Rosales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3744 NCBITaxon:3745 biolink:OrganismalEntity Rosaceae go-plus.json rose family|Malaceae http://purl.obolibrary.org/obo/NCBITaxon_3745 CHEBI:64643 biolink:ChemicalSubstance N(6)-[(3R)-3-methyl-D-ornithyl]-L-lysine(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64643 chebi_ph7_3 CHEBI:15629 biolink:ChemicalSubstance 8(R)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15629 CHEBI:64642 biolink:ChemicalSubstance (3R)-3-methyl-D-ornithine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64642 chebi_ph7_3 CHEBI:15628 biolink:ChemicalSubstance 15(S)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15628 CHEBI:64641 biolink:ChemicalSubstance divalent inorganic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_64641 CHEBI:64640 biolink:ChemicalSubstance hypusine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64640 CHEBI:15625 biolink:ChemicalSubstance S-adenosylmethioninamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15625 CHEBI:15624 biolink:ChemicalSubstance (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15624 CHEBI:64645 biolink:ChemicalSubstance amyloid-beta go-plus.json http://purl.obolibrary.org/obo/CHEBI_64645 CHEBI:15627 biolink:ChemicalSubstance thromboxane A2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15627 CHEBI:15626 biolink:ChemicalSubstance 12(S)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15626 CHEBI:15621 biolink:ChemicalSubstance (4-hydroxyphenyl)acetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15621 chebi_ph7_3 CHEBI:15620 biolink:ChemicalSubstance N-ethylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15620 CHEBI:15623 biolink:ChemicalSubstance 3-deoxy-D-glycero-hexo-2,5-diulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15623 CHEBI:15622 biolink:ChemicalSubstance 2,3-diketogulonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15622 CHEBI:64648 biolink:ChemicalSubstance enniatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64648 NCBITaxon:3754 biolink:OrganismalEntity Prunus go-plus.json Prunus subg. 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http://purl.obolibrary.org/obo/CHEBI_15616 CHEBI:15615 biolink:ChemicalSubstance (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15615 CHEBI:15610 biolink:ChemicalSubstance gibberellin A12 aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15610 CHEBI:88609 biolink:ChemicalSubstance (E)-2-dodecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_88609 chebi_ph7_3 CHEBI:15611 biolink:ChemicalSubstance sarcosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15611 NCBITaxon:3760 biolink:OrganismalEntity Prunus persica go-plus.json peach|Amygdalus persica|Persica vulgaris http://purl.obolibrary.org/obo/NCBITaxon_3760 CHEBI:49028 biolink:ChemicalSubstance acetimidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49028 CHEBI:50017 biolink:ChemicalSubstance arsonous acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_50017 CHEBI:50014 biolink:ChemicalSubstance (R,R)-hydrobenzoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50014 chebi_ph7_3 CHEBI:50018 biolink:ChemicalSubstance glycosyloxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50018 CHEBI:49020 biolink:ChemicalSubstance hormone antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_49020 CHEBI:49022 biolink:ChemicalSubstance beta-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49022 CHEBI:25051 biolink:ChemicalSubstance lipid As go-plus.json http://purl.obolibrary.org/obo/CHEBI_25051 CHEBI:49024 biolink:ChemicalSubstance alpha-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49024 CHEBI:49023 biolink:ChemicalSubstance prostaglandin antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_49023 CHEBI:49026 biolink:ChemicalSubstance N-acetyl-alpha-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49026 CHEBI:50013 biolink:ChemicalSubstance hydrobenzoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50013 chebi_ph7_3 CHEBI:50006 biolink:ChemicalSubstance stilbene oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50006 chebi_ph7_3 CHEBI:49017 biolink:ChemicalSubstance 3-methylthiopropanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_49017 chebi_ph7_3 CHEBI:49016 biolink:ChemicalSubstance 3-(methylthio)propionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49016 chebi_ph7_3 CHEBI:50004 biolink:ChemicalSubstance cis-stilbene oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50004 chebi_ph7_3 CHEBI:49019 biolink:ChemicalSubstance 3-methylthiopropanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49019 chebi_ph7_3 CHEBI:49018 biolink:ChemicalSubstance neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49018 CHEBI:50007 biolink:ChemicalSubstance antimony coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_50007 CHEBI:49015 biolink:ChemicalSubstance 1-piperideine-6-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49015 CHEBI:49014 biolink:ChemicalSubstance (S)-1-piperideine-6-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49014 PR:000036199 biolink:Protein non-peptidyl modified amino-acid residue An organic group that results from covalent modification or chemical alteration to the backbone atoms of amino acid residues so that their peptide bond is altered but the C1 and alpha-N bond is uncleaved. go-plus.json http://purl.obolibrary.org/obo/PR_000036199 PR:000036198 biolink:Protein peptidyl modified amino-acid residue An amino-acid residue that results from covalent modification or chemical alteration to the side chain or backbone atoms such that the peptide bonds remain. go-plus.json http://purl.obolibrary.org/obo/PR_000036198 CHEBI:49006 biolink:ChemicalSubstance N-acetylcitrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_49006 PR:000036194 biolink:Protein eukaryotic protein A protein that is encoded in the genome of some Eukaryota. go-plus.json Eukaryota protein http://purl.obolibrary.org/obo/PR_000036194 CHEBI:49008 biolink:ChemicalSubstance (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49008 CHEBI:49007 biolink:ChemicalSubstance D-citrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_49007 CHEBI:25036 biolink:ChemicalSubstance lignan go-plus.json http://purl.obolibrary.org/obo/CHEBI_25036 CHEBI:49009 biolink:ChemicalSubstance (1S,6R)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49009 CHEBI:40673 biolink:ChemicalSubstance L-2-amino-3-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_40673 CHEBI:49002 biolink:ChemicalSubstance N-acetyl-L-citrulline go-plus.json http://purl.obolibrary.org/obo/CHEBI_49002 CHEBI:49004 biolink:ChemicalSubstance N-acetyl-LL-2,6-diaminopimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49004 CHEBI:49003 biolink:ChemicalSubstance 4-phospho-D-erythronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49003 CHEBI:25048 biolink:ChemicalSubstance linolenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25048 NCBITaxon:376913 biolink:OrganismalEntity Haplorrhini go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_376913 CHEBI:25040 biolink:ChemicalSubstance limonene monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25040 CHEBI:25046 biolink:ChemicalSubstance linear tetrapyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_25046 CHEBI:40666 biolink:ChemicalSubstance 1,6-anhydro-N-acetyl-beta-muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_40666 CHEBI:25017 biolink:ChemicalSubstance leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25017 CHEBI:25016 biolink:ChemicalSubstance lead atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_25016 chebi_ph7_3 NCBITaxon:86661 biolink:OrganismalEntity Bacillus cereus group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_86661 CHEBI:25018 biolink:ChemicalSubstance L-leucine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_25018 NCBITaxon:72025 biolink:OrganismalEntity Fabales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_72025 CHEBI:15687 biolink:ChemicalSubstance (S)-acetoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15687 chebi_ph7_3 CHEBI:15686 biolink:ChemicalSubstance (R)-acetoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15686 chebi_ph7_3 CHEBI:40656 biolink:ChemicalSubstance beta-D-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_40656 chebi_ph7_3 CHEBI:15689 biolink:ChemicalSubstance 2,3-dihydroxy-3-methylbutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15689 CHEBI:15688 biolink:ChemicalSubstance acetoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15688 chebi_ph7_3 CHEBI:15683 biolink:ChemicalSubstance (R)-10-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15683 chebi_ph7_3 CHEBI:15682 biolink:ChemicalSubstance (N(omega)-L-arginino)succinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15682 CHEBI:15685 biolink:ChemicalSubstance L-2-succinylamino-6-oxoheptanedioate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15685 chebi_ph7_3 CHEBI:15684 biolink:ChemicalSubstance (R)-2,3-dihydroxy-3-methylbutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15684 CHEBI:15681 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15681 CHEBI:25029 biolink:ChemicalSubstance leukotriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_25029 CHEBI:25022 biolink:ChemicalSubstance leucomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25022 CHEBI:15679 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15679 CHEBI:15676 biolink:ChemicalSubstance allantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15676 chebi_ph7_3 CHEBI:15675 biolink:ChemicalSubstance (2R)-1-aminopropan-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15675 CHEBI:15678 biolink:ChemicalSubstance (S)-(+)-allantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15678 chebi_ph7_3 CHEBI:15677 biolink:ChemicalSubstance (R)-(-)-allantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15677 chebi_ph7_3 CHEBI:15672 biolink:ChemicalSubstance D-tartaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15672 CHEBI:15671 biolink:ChemicalSubstance L-tartaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15671 CHEBI:15674 biolink:ChemicalSubstance 2,3-dihydroxybutanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15674 CHEBI:15673 biolink:ChemicalSubstance meso-tartaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15673 CHEBI:15670 biolink:ChemicalSubstance (E)-glutaconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15670 UBERON:0012615 biolink:AnatomicalEntity umbilical smooth muscle A smooth muscle tissue that is part of a umbilical cord. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012615 CHEBI:8210 biolink:ChemicalSubstance pimara-8(14),15-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_8210 chebi_ph7_3 CHEBI:25004 biolink:ChemicalSubstance lactose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25004 CHEBI:25002 biolink:ChemicalSubstance lactosamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_25002 CHEBI:25000 biolink:ChemicalSubstance lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25000 CHEBI:15698 biolink:ChemicalSubstance 2'-deoxycytidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15698 chebi_ph7_3 CHEBI:15699 biolink:ChemicalSubstance L-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15699 CHEBI:15694 biolink:ChemicalSubstance (R)-S-lactoylglutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_15694 CHEBI:15693 biolink:ChemicalSubstance aldose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15693 chebi_ph7_3 CHEBI:15696 biolink:ChemicalSubstance beta-D-glucosyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15696 CHEBI:15695 biolink:ChemicalSubstance D-4-hydroxyphenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15695 CHEBI:15690 biolink:ChemicalSubstance 20-hydroxy-3-oxopregn-4-en-21-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_15690 chebi_ph7_3 CHEBI:15692 biolink:ChemicalSubstance 3'-demethylstaurosporine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15692 CHEBI:8225 biolink:ChemicalSubstance pinoresinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_8225 UBERON:4000020 biolink:AnatomicalEntity mineralized extracellular matrix Extracellular matrix that is mineralized. go-plus.json http://purl.obolibrary.org/obo/UBERON_4000020 GO:1904839 biolink:BiologicalProcess negative regulation of male germ-line stem cell asymmetric division Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division. go-plus.json inhibition of male germ-line stem cell asymmetric division|negative regulation of male germ-line stem cell renewal|down-regulation of male germ-line stem cell renewal|down-regulation of male germ-line stem cell asymmetric division|downregulation of male germ-line stem cell renewal|downregulation of male germ-line stem cell asymmetric division|down regulation of male germ-line stem cell renewal|down regulation of male germ-line stem cell asymmetric division|inhibition of male germ-line stem cell renewal http://purl.obolibrary.org/obo/GO_1904839 GO:1904838 biolink:BiologicalProcess regulation of male germ-line stem cell asymmetric division Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division. go-plus.json regulation of male germ-line stem cell renewal http://purl.obolibrary.org/obo/GO_1904838 GO:1904837 biolink:BiologicalProcess beta-catenin-TCF complex assembly The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex. go-plus.json beta-catenin-TCF complex formation|beta-catenin/lymphoid enhancer binding factor complex assembly|beta-catenin/LEF complex formation|beta-catenin/T-cell factor complex formation|beta-catenin/T-cell factor complex assembly|beta-catenin/lymphoid enhancer binding factor complex formation|beta-catenin/LEF complex assembly http://purl.obolibrary.org/obo/GO_1904837 GO:1904836 biolink:BiologicalProcess facioacoustic ganglion morphogenesis The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized. go-plus.json facio-acoustic VII-VIII ganglion complex morphogenesis|facio-acoustic ganglion complex VII-VIII morphogenesis|facio-acoustic ganglion morphogenesis|facio-acoustic ganglion complex morphogenesis|acousticofacial ganglion morphogenesis|acoustico-facial VII-VIII ganglion complex morphogenesis http://purl.obolibrary.org/obo/GO_1904836 GO:1904835 biolink:BiologicalProcess dorsal root ganglion morphogenesis The developmental process by which a dorsal root ganglion is generated and organized. go-plus.json ganglion sensorium nervi spinalis morphogenesis|ganglion spinalis morphogenesis|spinal ganglion part of peripheral nervous system morphogenesis|posterior root ganglion morphogenesis|spinal ganglion morphogenesis|ganglion spinale morphogenesis|dorsal root ganglia morphogenesis|DRG morphogenesis|ganglion of dorsal root morphogenesis http://purl.obolibrary.org/obo/GO_1904835 GO:1904834 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904834 CHEBI:132129 biolink:ChemicalSubstance (8S)-hepoxilin A3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132129 chebi_ph7_3 GO:1904833 biolink:BiologicalProcess positive regulation of removal of superoxide radicals Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals. go-plus.json positive regulation of removal of O2-|up regulation of removal of O2-|positive regulation of cellular detoxification of superoxide radicals|upregulation of removal of superoxide radicals|up regulation of removal of oxygen free radicals|up regulation of cellular detoxification of superoxide radicals|activation of removal of oxygen free radicals|positive regulation of removal of oxygen free radicals|upregulation of removal of O2-|up-regulation of removal of superoxide radicals|activation of removal of superoxide radicals|upregulation of cellular detoxification of superoxide radicals|up-regulation of removal of oxygen free radicals|activation of removal of O2-|up-regulation of removal of O2-|activation of cellular detoxification of superoxide radicals|up-regulation of cellular detoxification of superoxide radicals|up regulation of removal of superoxide radicals|upregulation of removal of oxygen free radicals http://purl.obolibrary.org/obo/GO_1904833 GO:1904832 biolink:BiologicalProcess negative regulation of removal of superoxide radicals Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals. go-plus.json down regulation of removal of oxygen free radicals|down-regulation of cellular detoxification of superoxide radicals|negative regulation of cellular detoxification of superoxide radicals|down regulation of removal of superoxide radicals|inhibition of removal of superoxide radicals|downregulation of removal of oxygen free radicals|downregulation of removal of O2-|downregulation of cellular detoxification of superoxide radicals|down regulation of removal of O2-|down-regulation of removal of oxygen free radicals|negative regulation of removal of oxygen free radicals|inhibition of removal of O2-|down regulation of cellular detoxification of superoxide radicals|inhibition of cellular detoxification of superoxide radicals|inhibition of removal of oxygen free radicals|down-regulation of removal of superoxide radicals|negative regulation of removal of O2-|down-regulation of removal of O2-|downregulation of removal of superoxide radicals http://purl.obolibrary.org/obo/GO_1904832 GO:1904831 biolink:BiologicalProcess positive regulation of aortic smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation. go-plus.json upregulation of aortic smooth muscle cell differentiation|up regulation of aortic smooth muscle cell differentiation|activation of aortic smooth muscle cell differentiation|up-regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1904831 GO:1904830 biolink:BiologicalProcess negative regulation of aortic smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation. go-plus.json down regulation of aortic smooth muscle cell differentiation|downregulation of aortic smooth muscle cell differentiation|down-regulation of aortic smooth muscle cell differentiation|inhibition of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1904830 CHEBI:132122 biolink:ChemicalSubstance S-(2-methyl-1-oxobut-3-en-2-yl)glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_132122 CHEBI:132124 biolink:ChemicalSubstance 1,4-benzoquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_132124 chebi_ph7_3 CHEBI:132123 biolink:ChemicalSubstance 1,2-benzoquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_132123 chebi_ph7_3 CHEBI:132125 biolink:ChemicalSubstance 2,4-didehydro-3-deoxy-L-rhamnonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132125 CHEBI:132128 biolink:ChemicalSubstance (3R)-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132128 CHEBI:132127 biolink:ChemicalSubstance hepoxilin A3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132127 chebi_ph7_3 UBERON:4000013 biolink:AnatomicalEntity mineralized skeletal tissue Skeletal tissue that is mineralized. go-plus.json mineralized tissue http://purl.obolibrary.org/obo/UBERON_4000013 CHEBI:132120 biolink:ChemicalSubstance resolvin go-plus.json http://purl.obolibrary.org/obo/CHEBI_132120 UBERON:6002639 biolink:AnatomicalEntity insect larval sense organ Any sense organ that is part of some larva. go-plus.json larval sense organ http://purl.obolibrary.org/obo/UBERON_6002639 CHEBI:8290 biolink:ChemicalSubstance Poly(G) go-plus.json http://purl.obolibrary.org/obo/CHEBI_8290 GO:1904849 biolink:BiologicalProcess positive regulation of cell chemotaxis to fibroblast growth factor Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. go-plus.json up regulation of cell chemotaxis to fibroblast growth factor|activation of cell chemotaxis to fibroblast growth factor|up-regulation of cell chemotaxis to fibroblast growth factor|upregulation of cell chemotaxis to fibroblast growth factor http://purl.obolibrary.org/obo/GO_1904849 GO:1904848 biolink:BiologicalProcess negative regulation of cell chemotaxis to fibroblast growth factor Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. go-plus.json down-regulation of cell chemotaxis to fibroblast growth factor|inhibition of cell chemotaxis to fibroblast growth factor|down regulation of cell chemotaxis to fibroblast growth factor|downregulation of cell chemotaxis to fibroblast growth factor http://purl.obolibrary.org/obo/GO_1904848 GO:1904847 biolink:BiologicalProcess regulation of cell chemotaxis to fibroblast growth factor Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_1904847 GO:1904846 biolink:BiologicalProcess negative regulation of establishment of bipolar cell polarity Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity. go-plus.json downregulation of establishment of bipolar cell polarity|down regulation of establishment of bipolar cell polarity|inhibition of establishment of bipolar cell polarity|down-regulation of establishment of bipolar cell polarity http://purl.obolibrary.org/obo/GO_1904846 GO:1904845 biolink:BiologicalProcess cellular response to L-glutamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904845 GO:1904844 biolink:BiologicalProcess response to L-glutamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904844 GO:1904843 biolink:BiologicalProcess cellular response to nitroglycerin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus. go-plus.json cellular response to nitroglycerine|cellular response to trinitroglycerin|cellular response to trinitroglycerol|cellular response to nitroglycerol http://purl.obolibrary.org/obo/GO_1904843 GO:1904842 biolink:BiologicalProcess response to nitroglycerin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus. go-plus.json response to trinitroglycerol|response to nitroglycerol|response to nitroglycerine|response to trinitroglycerin http://purl.obolibrary.org/obo/GO_1904842 GO:1904841 biolink:MolecularActivity TORC2 complex binding Binding to a TORC2 complex. go-plus.json TOR complex 2 binding|TORC 2 complex binding|TORC2 binding|rapamycin and nutrient-insensitive TOR complex binding|mTORC2 binding http://purl.obolibrary.org/obo/GO_1904841 GO:1904840 biolink:BiologicalProcess positive regulation of male germ-line stem cell asymmetric division Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division. go-plus.json up regulation of male germ-line stem cell renewal|up regulation of male germ-line stem cell asymmetric division|upregulation of male germ-line stem cell renewal|upregulation of male germ-line stem cell asymmetric division|up-regulation of male germ-line stem cell renewal|activation of male germ-line stem cell renewal|up-regulation of male germ-line stem cell asymmetric division|activation of male germ-line stem cell asymmetric division|positive regulation of male germ-line stem cell renewal http://purl.obolibrary.org/obo/GO_1904840 CHEBI:132137 biolink:ChemicalSubstance (R)-demethyl-4-deoxygadusol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132137 CHEBI:132139 biolink:ChemicalSubstance (R)-demethyl-4-deoxygadusol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132139 chebi_ph7_3 CHEBI:132131 biolink:ChemicalSubstance 3,5-dimethylorsellinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132131 CHEBI:132130 biolink:ChemicalSubstance hydroxyquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_132130 GO:1904859 biolink:BiologicalProcess positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor. go-plus.json up-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|upregulation of endothelial cell chemotaxis to vascular endothelial growth factor|up regulation of endothelial cell chemotaxis to vascular endothelial growth factor|activation of endothelial cell chemotaxis to vascular endothelial growth factor http://purl.obolibrary.org/obo/GO_1904859 GO:1904858 biolink:BiologicalProcess negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor. go-plus.json down-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|inhibition of endothelial cell chemotaxis to vascular endothelial growth factor|down regulation of endothelial cell chemotaxis to vascular endothelial growth factor|downregulation of endothelial cell chemotaxis to vascular endothelial growth factor http://purl.obolibrary.org/obo/GO_1904858 GO:1904857 biolink:BiologicalProcess regulation of endothelial cell chemotaxis to vascular endothelial growth factor Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor. go-plus.json http://purl.obolibrary.org/obo/GO_1904857 GO:1904856 biolink:CellularComponent cytolytic granule lumen Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule. go-plus.json cytolytic granule cytoplasmic membrane-bounded vesicle lumen|cytoplasmic membrane-enclosed vesicle lumen of cytolytic granule|cytoplasmic membrane-bounded vesicle lumen of cytolytic granule http://purl.obolibrary.org/obo/GO_1904856 GO:1904855 biolink:MolecularActivity proteasome regulatory particle binding Binding to a proteasome regulatory particle. go-plus.json 19S regulatory particle binding|modulator complex binding|PA700-dependent proteasome activator binding|PA700 proteasome activator binding http://purl.obolibrary.org/obo/GO_1904855 GO:1904854 biolink:MolecularActivity proteasome core complex binding Binding to a proteasome core complex. go-plus.json 20S proteasome binding|PA28gamma-20S proteasome binding|macropain binding|20S core complex binding http://purl.obolibrary.org/obo/GO_1904854 GO:1904853 biolink:BiologicalProcess protein localization to ascospore wall A process in which a protein is transported to, or maintained in, a location within an ascospore wall. go-plus.json protein localisation to ascospore wall|protein localisation in ascospore wall|protein localization in ascospore wall http://purl.obolibrary.org/obo/GO_1904853 GO:1904852 biolink:CellularComponent trimethylamine-N-oxide reductase (cytochrome c) complex A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904852 GO:1904851 biolink:BiologicalProcess positive regulation of establishment of protein localization to telomere Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere. go-plus.json upregulation of establishment of protein localization to chromosome, telomeric region|upregulation of establishment of protein localization to telomere|up regulation of establishment of protein localisation to telomere|activation of establishment of protein localisation to telomere|positive regulation of establishment of protein localisation to telomere|up regulation of establishment of protein localization to chromosome, telomeric region|activation of establishment of protein localization to chromosome, telomeric region|up regulation of establishment of protein localization to telomere|activation of establishment of protein localization to telomere|positive regulation of establishment of protein localization to chromosome, telomeric region|up-regulation of establishment of protein localisation to telomere|up-regulation of establishment of protein localization to chromosome, telomeric region|up-regulation of establishment of protein localization to telomere|upregulation of establishment of protein localisation to telomere http://purl.obolibrary.org/obo/GO_1904851 GO:1904850 biolink:BiologicalProcess negative regulation of establishment of protein localization to telomere Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere. go-plus.json downregulation of establishment of protein localisation to telomere|down regulation of establishment of protein localization to chromosome, telomeric region|down regulation of establishment of protein localization to telomere|downregulation of establishment of protein localization to chromosome, telomeric region|downregulation of establishment of protein localization to telomere|down-regulation of establishment of protein localisation to telomere|negative regulation of establishment of protein localisation to telomere|negative regulation of establishment of protein localization to chromosome, telomeric region|down-regulation of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localisation to telomere|down-regulation of establishment of protein localization to telomere|inhibition of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localization to telomere|down regulation of establishment of protein localisation to telomere http://purl.obolibrary.org/obo/GO_1904850 GO:1904860 biolink:BiologicalProcess DNA synthesis involved in mitotic DNA replication Any DNA biosynthetic process that is involved in mitotic DNA replication. go-plus.json DNA anabolism involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in DNA replication during S phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in DNA replication during S phase involved in mitotic cell cycle|DNA formation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA formation involved in mitotic cell cycle DNA replication|DNA biosynthesis involved in mitotic DNA replication|DNA formation involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in mitotic cell cycle DNA replication|DNA formation involved in mitotic nuclear cell cycle DNA replication|DNA synthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA formation involved in DNA replication during S phase involved in mitotic cell cycle|DNA anabolism involved in mitotic cell cycle DNA replication|DNA anabolism involved in mitotic DNA replication|DNA synthesis involved in mitotic nuclear cell cycle DNA replication|DNA anabolism involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic cell cycle DNA replication|DNA anabolism involved in mitotic nuclear cell cycle DNA replication|DNA biosynthesis involved in mitotic cell cycle DNA replication|DNA formation involved in mitotic DNA replication|DNA biosynthetic process involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA formation involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthetic process involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic DNA replication|DNA biosynthetic process involved in mitotic nuclear cell cycle DNA replication|DNA synthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in mitotic nuclear cell cycle DNA replication http://purl.obolibrary.org/obo/GO_1904860 CHEBI:132104 biolink:ChemicalSubstance O(3)-(N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132104 chebi_ph7_3 CHEBI:132105 biolink:ChemicalSubstance O(3)-(N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132105 chebi_ph7_3 CHEBI:8273 biolink:ChemicalSubstance plumbagin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8273 chebi_ph7_3 GO:1904869 biolink:BiologicalProcess regulation of protein localization to Cajal body Any process that modulates the frequency, rate or extent of protein localization to Cajal body. go-plus.json regulation of protein localisation in Cajal body|regulation of protein localization in Cajal body|regulation of protein localisation to Cajal body http://purl.obolibrary.org/obo/GO_1904869 GO:1904868 biolink:BiologicalProcess telomerase catalytic core complex assembly The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex. go-plus.json telomerase catalytic core complex formation|TERT-TERC complex formation|TERT-TERC complex assembly http://purl.obolibrary.org/obo/GO_1904868 GO:1904867 biolink:BiologicalProcess protein localization to Cajal body A process in which a protein is transported to, or maintained in, a location within a Cajal body. go-plus.json protein localization in Cajal body|protein localisation to Cajal body|protein localisation in Cajal body http://purl.obolibrary.org/obo/GO_1904867 CHEBI:132118 biolink:ChemicalSubstance S-(2-carboxy-2-methylbut-3-en-2-yl)glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_132118 GO:1904866 biolink:BiologicalProcess ventral tegmental area development The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure. go-plus.json a10a development|ventral tegmental nucleus (tsai) development|VTA development|ventral tegmental area of tsai development|ventral tegmental area (Tsai) development|ventral tegmentum development|area tegmentalis ventralis (Tsai) development|tegmentum ventrale development|ventral tegmental nucleus of tsai development|ventral tegmental nucleus (Rioch) development|ventral brain stem development|ventromedial mesencephalic tegmentum development|area tegmentalis ventralis development http://purl.obolibrary.org/obo/GO_1904866 GO:1904865 biolink:BiologicalProcess positive regulation of beta-catenin-TCF complex assembly Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly. go-plus.json positive regulation of beta-catenin/LEF complex assembly|activation of beta-catenin/lymphoid enhancer binding factor complex formation|upregulation of beta-catenin/LEF complex formation|activation of beta-catenin/LEF complex assembly|upregulation of beta-catenin/T-cell factor complex assembly|up-regulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|activation of beta-catenin-TCF complex formation|upregulation of beta-catenin-TCF complex assembly|upregulation of beta-catenin/T-cell factor complex formation|up-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|up-regulation of beta-catenin/LEF complex assembly|up-regulation of beta-catenin/LEF complex formation|activation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin-TCF complex assembly|up-regulation of beta-catenin/T-cell factor complex formation|up regulation of beta-catenin/T-cell factor complex assembly|positive regulation of beta-catenin-TCF complex formation|activation of beta-catenin-TCF complex assembly|positive regulation of beta-catenin/T-cell factor complex assembly|activation of beta-catenin/LEF complex formation|positive regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|up regulation of beta-catenin-TCF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin/LEF complex assembly|activation of beta-catenin/T-cell factor complex formation|activation of beta-catenin/T-cell factor complex assembly|positive regulation of beta-catenin/LEF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin/LEF complex formation|positive regulation of beta-catenin/T-cell factor complex formation|positive regulation of beta-catenin/lymphoid enhancer binding factor complex formation|upregulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/T-cell factor complex assembly|up regulation of beta-catenin/T-cell factor complex formation|up-regulation of beta-catenin-TCF complex assembly|up regulation of beta-catenin/LEF complex assembly|upregulation of beta-catenin/lymphoid enhancer binding factor complex assembly http://purl.obolibrary.org/obo/GO_1904865 GO:1904864 biolink:BiologicalProcess negative regulation of beta-catenin-TCF complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly. go-plus.json down regulation of beta-catenin/LEF complex formation|inhibition of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin/T-cell factor complex assembly|down regulation of beta-catenin/T-cell factor complex formation|negative regulation of beta-catenin/LEF complex assembly|down-regulation of beta-catenin/LEF complex assembly|inhibition of beta-catenin/LEF complex formation|down regulation of beta-catenin/T-cell factor complex assembly|down regulation of beta-catenin-TCF complex assembly|inhibition of beta-catenin/T-cell factor complex formation|inhibition of beta-catenin/lymphoid enhancer binding factor complex formation|downregulation of beta-catenin/T-cell factor complex assembly|negative regulation of beta-catenin-TCF complex formation|downregulation of beta-catenin-TCF complex assembly|down-regulation of beta-catenin-TCF complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin/LEF complex assembly|down regulation of beta-catenin/lymphoid enhancer binding factor complex formation|down-regulation of beta-catenin/LEF complex formation|negative regulation of beta-catenin/LEF complex formation|down-regulation of beta-catenin/T-cell factor complex assembly|negative regulation of beta-catenin/T-cell factor complex assembly|downregulation of beta-catenin-TCF complex formation|downregulation of beta-catenin/lymphoid enhancer binding factor complex formation|down-regulation of beta-catenin-TCF complex assembly|downregulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/T-cell factor complex formation|negative regulation of beta-catenin/T-cell factor complex formation|down regulation of beta-catenin/LEF complex assembly|down regulation of beta-catenin-TCF complex formation|down regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin-TCF complex formation|downregulation of beta-catenin/LEF complex assembly|inhibition of beta-catenin-TCF complex assembly|downregulation of beta-catenin/LEF complex formation|down-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex formation|downregulation of beta-catenin/T-cell factor complex formation http://purl.obolibrary.org/obo/GO_1904864 GO:1904863 biolink:BiologicalProcess regulation of beta-catenin-TCF complex assembly Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly. go-plus.json regulation of beta-catenin/T-cell factor complex formation|regulation of beta-catenin/T-cell factor complex assembly|regulation of beta-catenin/lymphoid enhancer binding factor complex formation|regulation of beta-catenin-TCF complex formation|regulation of beta-catenin/LEF complex assembly|regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|regulation of beta-catenin/LEF complex formation http://purl.obolibrary.org/obo/GO_1904863 GO:1904862 biolink:BiologicalProcess inhibitory synapse assembly The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse. go-plus.json inhibitory synapse formation http://purl.obolibrary.org/obo/GO_1904862 GO:1904861 biolink:BiologicalProcess excitatory synapse assembly The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse. go-plus.json excitatory synapse formation http://purl.obolibrary.org/obo/GO_1904861 GO:1904871 biolink:BiologicalProcess positive regulation of protein localization to Cajal body Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body. go-plus.json up-regulation of protein localisation in Cajal body|activation of protein localisation in Cajal body|positive regulation of protein localisation to Cajal body|up regulation of protein localisation to Cajal body|up-regulation of protein localization in Cajal body|activation of protein localization in Cajal body|up regulation of protein localization to Cajal body|positive regulation of protein localisation in Cajal body|upregulation of protein localisation to Cajal body|up regulation of protein localisation in Cajal body|positive regulation of protein localization in Cajal body|up regulation of protein localization in Cajal body|upregulation of protein localization to Cajal body|up-regulation of protein localisation to Cajal body|upregulation of protein localisation in Cajal body|activation of protein localisation to Cajal body|up-regulation of protein localization to Cajal body|upregulation of protein localization in Cajal body|activation of protein localization to Cajal body http://purl.obolibrary.org/obo/GO_1904871 GO:1904870 biolink:BiologicalProcess negative regulation of protein localization to Cajal body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body. go-plus.json down-regulation of protein localization to Cajal body|downregulation of protein localisation to Cajal body|negative regulation of protein localisation in Cajal body|down-regulation of protein localisation in Cajal body|down regulation of protein localisation to Cajal body|inhibition of protein localisation to Cajal body|downregulation of protein localization to Cajal body|negative regulation of protein localization in Cajal body|down-regulation of protein localization in Cajal body|downregulation of protein localisation in Cajal body|down regulation of protein localization to Cajal body|inhibition of protein localization to Cajal body|down regulation of protein localisation in Cajal body|inhibition of protein localisation in Cajal body|downregulation of protein localization in Cajal body|down regulation of protein localization in Cajal body|inhibition of protein localization in Cajal body|negative regulation of protein localisation to Cajal body|down-regulation of protein localisation to Cajal body http://purl.obolibrary.org/obo/GO_1904870 CHEBI:132115 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132115 chebi_ph7_3 CHEBI:132114 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-galactosamine 4-sulfate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132114 chebi_ph7_3 CHEBI:132117 biolink:ChemicalSubstance indolmycenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132117 CHEBI:132116 biolink:ChemicalSubstance 2-hydroxyisobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_132116 GO:1904879 biolink:BiologicalProcess positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel. go-plus.json up-regulation of generation of L-type calcium current|positive regulation of generation of L-type calcium current|activation of generation of L-type calcium current|up regulation of generation of L-type calcium current|upregulation of generation of L-type calcium current http://purl.obolibrary.org/obo/GO_1904879 GO:1904878 biolink:BiologicalProcess negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel. go-plus.json negative regulation of generation of L-type calcium current|down-regulation of generation of L-type calcium current|downregulation of generation of L-type calcium current|down regulation of generation of L-type calcium current|inhibition of generation of L-type calcium current http://purl.obolibrary.org/obo/GO_1904878 GO:1904877 biolink:BiologicalProcess positive regulation of DNA ligase activity Any process that activates or increases the frequency, rate or extent of DNA ligase activity. go-plus.json up regulation of DNA ligase activity|activation of DNA ligase activity|up-regulation of DNA ligase activity|upregulation of DNA ligase activity http://purl.obolibrary.org/obo/GO_1904877 GO:1904876 biolink:BiologicalProcess negative regulation of DNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity. go-plus.json downregulation of DNA ligase activity|down-regulation of DNA ligase activity|inhibition of DNA ligase activity|down regulation of DNA ligase activity http://purl.obolibrary.org/obo/GO_1904876 GO:1904875 biolink:BiologicalProcess regulation of DNA ligase activity Any process that modulates the frequency, rate or extent of DNA ligase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904875 GO:1904874 biolink:BiologicalProcess positive regulation of telomerase RNA localization to Cajal body Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body. go-plus.json upregulation of telomerase RNA localization to Cajal body|up regulation of telomerase RNA localization to Cajal body|activation of telomerase RNA localization to Cajal body|up-regulation of telomerase RNA localization to Cajal body http://purl.obolibrary.org/obo/GO_1904874 GO:1904873 biolink:BiologicalProcess negative regulation of telomerase RNA localization to Cajal body Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body. go-plus.json down regulation of telomerase RNA localization to Cajal body|downregulation of telomerase RNA localization to Cajal body|down-regulation of telomerase RNA localization to Cajal body|inhibition of telomerase RNA localization to Cajal body http://purl.obolibrary.org/obo/GO_1904873 GO:1904872 biolink:BiologicalProcess regulation of telomerase RNA localization to Cajal body Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body. go-plus.json http://purl.obolibrary.org/obo/GO_1904872 GO:1904882 biolink:BiologicalProcess regulation of telomerase catalytic core complex assembly Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly. go-plus.json regulation of telomerase catalytic core complex formation|regulation of TERT-TERC complex assembly|regulation of TERT-TERC complex formation http://purl.obolibrary.org/obo/GO_1904882 GO:1904881 biolink:BiologicalProcess cellular response to hydrogen sulfide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus. go-plus.json cellular response to sulfane|cellular response to dihydridosulfur http://purl.obolibrary.org/obo/GO_1904881 GO:1904880 biolink:BiologicalProcess response to hydrogen sulfide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus. go-plus.json response to dihydridosulfur|response to sulfane http://purl.obolibrary.org/obo/GO_1904880 GO:1904889 biolink:BiologicalProcess regulation of excitatory synapse assembly Any process that modulates the frequency, rate or extent of excitatory synapse assembly. go-plus.json regulation of excitatory synapse formation http://purl.obolibrary.org/obo/GO_1904889 GO:1904888 biolink:BiologicalProcess cranial skeletal system development The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. go-plus.json cranial skeleton development|osteocranium development|craniofacial development|cranium development http://purl.obolibrary.org/obo/GO_1904888 GO:1904887 biolink:BiologicalProcess Wnt signalosome assembly The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome. go-plus.json Wnt signalosome complex formation|LRP5/6 signalosome assembly|Wnt-LRP5/6 signalosome formation|Wnt signalosome formation|Wnt-LRP5/6 signalosome assembly|LRP6 signalosome assembly|Wnt signalosome complex assembly|LRP6 signalosome formation|LRP5/6 signalosome formation http://purl.obolibrary.org/obo/GO_1904887 GO:1904886 biolink:BiologicalProcess beta-catenin destruction complex disassembly The disaggregation of a beta-catenin destruction complex into its constituent components. go-plus.json Axin-APC-beta-catenin-GSK3B complex disassembly|BDC disassembly|beta-catenin degradation complex disassembly|23S APC complex disassembly|APC-Axin-1-beta-catenin complex disassembly|dissociation of beta-catenin degradation complex http://purl.obolibrary.org/obo/GO_1904886 GO:1904885 biolink:BiologicalProcess beta-catenin destruction complex assembly The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex. go-plus.json 23S APC complex assembly|Axin-APC-beta-catenin-GSK3B complex formation|BDC formation|beta-catenin degradation complex formation|23S APC complex formation|beta-catenin degradation complex assembly|destruction complex formation|BDC assembly|Axin-APC-beta-catenin-GSK3B complex assembly|APC-Axin-1-beta-catenin complex formation|APC-Axin-1-beta-catenin complex assembly|beta-catenin destruction complex formation http://purl.obolibrary.org/obo/GO_1904885 GO:1904884 biolink:BiologicalProcess positive regulation of telomerase catalytic core complex assembly Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly. go-plus.json up-regulation of telomerase catalytic core complex formation|activation of TERT-TERC complex assembly|up-regulation of TERT-TERC complex formation|up regulation of telomerase catalytic core complex assembly|positive regulation of TERT-TERC complex assembly|upregulation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex assembly|upregulation of TERT-TERC complex formation|upregulation of telomerase catalytic core complex assembly|up regulation of telomerase catalytic core complex formation|upregulation of TERT-TERC complex assembly|positive regulation of telomerase catalytic core complex formation|activation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex formation|up-regulation of telomerase catalytic core complex assembly|positive regulation of TERT-TERC complex formation|activation of telomerase catalytic core complex assembly|up-regulation of TERT-TERC complex assembly|activation of TERT-TERC complex formation http://purl.obolibrary.org/obo/GO_1904884 GO:1904883 biolink:BiologicalProcess negative regulation of telomerase catalytic core complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly. go-plus.json down-regulation of telomerase catalytic core complex assembly|inhibition of telomerase catalytic core complex formation|negative regulation of TERT-TERC complex assembly|down-regulation of TERT-TERC complex assembly|downregulation of telomerase catalytic core complex assembly|inhibition of TERT-TERC complex formation|down regulation of telomerase catalytic core complex formation|down regulation of telomerase catalytic core complex assembly|downregulation of TERT-TERC complex assembly|inhibition of telomerase catalytic core complex assembly|downregulation of telomerase catalytic core complex formation|down regulation of TERT-TERC complex formation|down regulation of TERT-TERC complex assembly|downregulation of TERT-TERC complex formation|down-regulation of telomerase catalytic core complex formation|negative regulation of telomerase catalytic core complex formation|inhibition of TERT-TERC complex assembly|down-regulation of TERT-TERC complex formation|negative regulation of TERT-TERC complex formation http://purl.obolibrary.org/obo/GO_1904883 GO:1904893 biolink:BiologicalProcess negative regulation of receptor signaling pathway via STAT Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT. go-plus.json down-regulation of STAT cascade|negative regulation of kinase activated-STAT cascade|down-regulation of kinase activated-STAT cascade|down regulation of STAT signalling pathway|down regulation of kinase-STAT cascade|downregulation of STAT signalling pathway|downregulation of kinase-STAT cascade|downregulation of STAT cascade|inhibition of kinase activated-STAT cascade|down regulation of STAT cascade|inhibition of STAT cascade|down-regulation of STAT signalling pathway|negative regulation of STAT signalling pathway|down-regulation of kinase-STAT cascade|negative regulation of kinase-STAT cascade|down regulation of kinase activated-STAT cascade|inhibition of STAT signalling pathway|inhibition of kinase-STAT cascade|downregulation of kinase activated-STAT cascade http://purl.obolibrary.org/obo/GO_1904893 GO:1904892 biolink:BiologicalProcess regulation of receptor signaling pathway via STAT Any process that modulates the frequency, rate or extent of receptor signaling via STAT. go-plus.json regulation of STAT signalling pathway|regulation of kinase-STAT cascade|regulation of kinase activated-STAT cascade http://purl.obolibrary.org/obo/GO_1904892 GO:1904891 biolink:BiologicalProcess positive regulation of excitatory synapse assembly Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly. go-plus.json up regulation of excitatory synapse assembly|positive regulation of excitatory synapse formation|activation of excitatory synapse assembly|up regulation of excitatory synapse formation|upregulation of excitatory synapse formation|up-regulation of excitatory synapse assembly|upregulation of excitatory synapse assembly|up-regulation of excitatory synapse formation|activation of excitatory synapse formation http://purl.obolibrary.org/obo/GO_1904891 GO:1904890 biolink:BiologicalProcess negative regulation of excitatory synapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly. go-plus.json down regulation of excitatory synapse assembly|downregulation of excitatory synapse assembly|negative regulation of excitatory synapse formation|down-regulation of excitatory synapse formation|downregulation of excitatory synapse formation|down-regulation of excitatory synapse assembly|down regulation of excitatory synapse formation|inhibition of excitatory synapse formation|inhibition of excitatory synapse assembly http://purl.obolibrary.org/obo/GO_1904890 GO:1904899 biolink:BiologicalProcess positive regulation of hepatic stellate cell proliferation Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation. go-plus.json positive regulation of perisinusoidal cell proliferation|positive regulation of hepatic perisinusoidal cell proliferation|up regulation of hepatic stellate cell proliferation|activation of hepatic stellate cell proliferation|positive regulation of Ito cell proliferation|up regulation of Ito cell proliferation|up-regulation of perisinusoidal cell proliferation|up-regulation of hepatic perisinusoidal cell proliferation|up-regulation of hepatic stellate cell proliferation|upregulation of Ito cell proliferation|upregulation of perisinusoidal cell proliferation|upregulation of hepatic perisinusoidal cell proliferation|upregulation of hepatic stellate cell proliferation|activation of Ito cell proliferation|up-regulation of Ito cell proliferation|up regulation of perisinusoidal cell proliferation|up regulation of hepatic perisinusoidal cell proliferation|activation of hepatic perisinusoidal cell proliferation|activation of perisinusoidal cell proliferation http://purl.obolibrary.org/obo/GO_1904899 GO:1904898 biolink:BiologicalProcess negative regulation of hepatic stellate cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation. go-plus.json negative regulation of Ito cell proliferation|down-regulation of Ito cell proliferation|down-regulation of hepatic perisinusoidal cell proliferation|negative regulation of hepatic perisinusoidal cell proliferation|down-regulation of perisinusoidal cell proliferation|negative regulation of perisinusoidal cell proliferation|down-regulation of hepatic stellate cell proliferation|downregulation of Ito cell proliferation|inhibition of hepatic perisinusoidal cell proliferation|inhibition of perisinusoidal cell proliferation|inhibition of hepatic stellate cell proliferation|down regulation of Ito cell proliferation|inhibition of Ito cell proliferation|down regulation of perisinusoidal cell proliferation|down regulation of hepatic perisinusoidal cell proliferation|down regulation of hepatic stellate cell proliferation|downregulation of perisinusoidal cell proliferation|downregulation of hepatic perisinusoidal cell proliferation|downregulation of hepatic stellate cell proliferation http://purl.obolibrary.org/obo/GO_1904898 GO:1904897 biolink:BiologicalProcess regulation of hepatic stellate cell proliferation Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation. go-plus.json regulation of Ito cell proliferation|regulation of hepatic perisinusoidal cell proliferation|regulation of perisinusoidal cell proliferation http://purl.obolibrary.org/obo/GO_1904897 GO:1904896 biolink:BiologicalProcess ESCRT complex disassembly The disaggregation of an ESCRT complex into its constituent components. go-plus.json endosomal sorting complex required for transport disassembly http://purl.obolibrary.org/obo/GO_1904896 GO:1904895 biolink:BiologicalProcess ESCRT complex assembly The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex. go-plus.json endosomal sorting complex required for transport formation|ESCRT complex formation|endosomal sorting complex required for transport assembly http://purl.obolibrary.org/obo/GO_1904895 GO:1904894 biolink:BiologicalProcess positive regulation of receptor signaling pathway via STAT Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT. go-plus.json positive regulation of kinase activated-STAT cascade|upregulation of STAT signalling pathway|upregulation of kinase-STAT cascade|up regulation of STAT cascade|up-regulation of kinase activated-STAT cascade|up regulation of STAT signalling pathway|activation of STAT signalling pathway|up regulation of kinase-STAT cascade|positive regulation of STAT signalling pathway|activation of kinase-STAT cascade|positive regulation of kinase-STAT cascade|upregulation of STAT cascade|upregulation of kinase activated-STAT cascade|up-regulation of STAT signalling pathway|up-regulation of kinase-STAT cascade|up-regulation of STAT cascade|activation of STAT cascade|up regulation of kinase activated-STAT cascade|activation of kinase activated-STAT cascade http://purl.obolibrary.org/obo/GO_1904894 CHEBI:8298 biolink:ChemicalSubstance poly[(R)-3-hydroxybutanoate] go-plus.json http://purl.obolibrary.org/obo/CHEBI_8298 chebi_ph7_3 CHEBI:64543 biolink:ChemicalSubstance fonsecin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64543 chebi_ph7_3 CHEBI:64542 biolink:ChemicalSubstance naphtho-gamma-pyrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64542 CHEBI:64548 biolink:ChemicalSubstance pyrazinoquinazoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_64548 CHEBI:88514 biolink:ChemicalSubstance butyl formate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88514 chebi_ph7_3 CHEBI:64547 biolink:ChemicalSubstance imidazoindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_64547 CHEBI:64546 biolink:ChemicalSubstance fumiquinazoline A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64546 chebi_ph7_3 CHEBI:64545 biolink:ChemicalSubstance fumiquinazoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_64545 CHEBI:64549 biolink:ChemicalSubstance lysophosphatidylcholine 18:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64549 chebi_ph7_3 NCBITaxon:13773 biolink:OrganismalEntity Pyrobaculum aerophilum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_13773 CHEBI:64551 biolink:ChemicalSubstance fumiquinazoline C go-plus.json http://purl.obolibrary.org/obo/CHEBI_64551 chebi_ph7_3 CHEBI:64550 biolink:ChemicalSubstance fumiquinazoline F go-plus.json http://purl.obolibrary.org/obo/CHEBI_64550 chebi_ph7_3 CHEBI:64555 biolink:ChemicalSubstance trans-p-coumaryl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64555 chebi_ph7_3 CHEBI:64554 biolink:ChemicalSubstance tryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64554 chebi_ph7_3 CHEBI:64553 biolink:ChemicalSubstance tatiopterin(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64553 chebi_ph7_3 CHEBI:64552 biolink:ChemicalSubstance 2-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64552 chebi_ph7_3 CHEBI:64558 biolink:ChemicalSubstance methionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64558 chebi_ph7_3 CHEBI:64557 biolink:ChemicalSubstance trans-sinapyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64557 chebi_ph7_3 CHEBI:64561 biolink:ChemicalSubstance lysophosphatidylcholine 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64561 chebi_ph7_3 CHEBI:64560 biolink:ChemicalSubstance lysophosphatidylcholine 16:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64560 chebi_ph7_3 CHEBI:64566 biolink:ChemicalSubstance lysophosphatidylcholine 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64566 chebi_ph7_3 CHEBI:64565 biolink:ChemicalSubstance lysophosphatidylcholine 18:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64565 chebi_ph7_3 CHEBI:64563 biolink:ChemicalSubstance lysophosphatidylcholine 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64563 chebi_ph7_3 CHEBI:132188 biolink:ChemicalSubstance methionine sulfone go-plus.json http://purl.obolibrary.org/obo/CHEBI_132188 CHEBI:64569 biolink:ChemicalSubstance lysophosphatidylethanolamine 20:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64569 CHEBI:64568 biolink:ChemicalSubstance lysophosphatidylcholine 20:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64568 chebi_ph7_3 CHEBI:64567 biolink:ChemicalSubstance lysophosphatidylcholine 22:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64567 chebi_ph7_3 CHEBI:132183 biolink:ChemicalSubstance (3S)-hydroxyadipyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132183 chebi_ph7_3 CHEBI:64573 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64573 chebi_ph7_3 CHEBI:64572 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64572 chebi_ph7_3 CHEBI:64571 biolink:ChemicalSubstance NMDA receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_64571 CHEBI:64570 biolink:ChemicalSubstance EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64570 CHEBI:64577 biolink:ChemicalSubstance flour treatment agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_64577 CHEBI:64576 biolink:ChemicalSubstance lysophosphatidylethanolamine 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64576 CHEBI:64575 biolink:ChemicalSubstance lysophosphatidylethanolamine 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64575 CHEBI:64574 biolink:ChemicalSubstance lysophosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64574 CHEBI:132198 biolink:ChemicalSubstance pentahydroxyanthraquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_132198 CHEBI:88528 biolink:ChemicalSubstance hexanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_88528 chebi_ph7_3 CHEBI:64584 biolink:ChemicalSubstance uremic toxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64584 CHEBI:64583 biolink:ChemicalSubstance sphingomyelin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64583 chebi_ph7_3 NCBITaxon:3803 biolink:OrganismalEntity Fabaceae go-plus.json Leguminosae|pea family http://purl.obolibrary.org/obo/NCBITaxon_3803 CHEBI:64588 biolink:ChemicalSubstance glycine transporter 1 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64588 CHEBI:156132 biolink:ChemicalSubstance L-thialysinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_156132 chebi_ph7_3 CHEBI:64589 biolink:ChemicalSubstance glycine receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_64589 GO:1904809 biolink:BiologicalProcess regulation of dense core granule transport Any process that modulates the frequency, rate or extent of dense core granule transport. go-plus.json regulation of dense core vesicle transport http://purl.obolibrary.org/obo/GO_1904809 GO:1904808 biolink:BiologicalProcess positive regulation of protein oxidation Any process that activates or increases the frequency, rate or extent of protein oxidation. go-plus.json positive regulation of protein amino acid oxidation|upregulation of protein oxidation|up regulation of protein amino acid oxidation|up regulation of protein oxidation|activation of protein oxidation|upregulation of protein amino acid oxidation|activation of protein amino acid oxidation|up-regulation of protein amino acid oxidation|up-regulation of protein oxidation http://purl.obolibrary.org/obo/GO_1904808 GO:1904807 biolink:BiologicalProcess negative regulation of protein oxidation Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation. go-plus.json down regulation of protein oxidation|downregulation of protein amino acid oxidation|downregulation of protein oxidation|down regulation of protein amino acid oxidation|inhibition of protein amino acid oxidation|down-regulation of protein oxidation|inhibition of protein oxidation|down-regulation of protein amino acid oxidation|negative regulation of protein amino acid oxidation http://purl.obolibrary.org/obo/GO_1904807 CHEBI:64591 biolink:ChemicalSubstance lysophosphatidylcholine O-18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64591 chebi_ph7_3 GO:1904806 biolink:BiologicalProcess regulation of protein oxidation Any process that modulates the frequency, rate or extent of protein oxidation. go-plus.json regulation of protein amino acid oxidation http://purl.obolibrary.org/obo/GO_1904806 CHEBI:64590 biolink:ChemicalSubstance monoalkyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64590 chebi_ph7_3 GO:1904805 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904805 GO:1904804 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904804 GO:1904803 biolink:BiologicalProcess regulation of translation involved in cellular response to UV Any regulation of translation that is involved in cellular response to UV. go-plus.json regulation of translation involved in cellular response to ultraviolet radiation stimulus|regulation of protein anabolism involved in cellular response to UV|regulation of translation involved in cellular response to UV radiation stimulus|regulation of protein synthesis involved in cellular response to UV|regulation of protein formation involved in cellular response to UV|regulation of protein biosynthesis involved in cellular response to UV|regulation of translation involved in cellular response to ultraviolet light stimulus|regulation of translation involved in cellular response to UV light stimulus http://purl.obolibrary.org/obo/GO_1904803 GO:1904802 biolink:BiologicalProcess RITS complex assembly The aggregation, arrangement and bonding together of a set of components to form a RITS complex. go-plus.json RITS complex formation http://purl.obolibrary.org/obo/GO_1904802 CHEBI:64595 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64595 GO:1904801 biolink:BiologicalProcess positive regulation of neuron remodeling Any process that activates or increases the frequency, rate or extent of neuron remodeling. go-plus.json activation of axon pruning|up regulation of neuron remodeling|upregulation of neuronal remodeling|activation of neuron remodeling|positive regulation of axon pruning|up regulation of axon pruning|up regulation of neuronal remodeling|up-regulation of neuron remodeling|activation of neuronal remodeling|positive regulation of neuronal remodeling|upregulation of axon pruning|upregulation of neuron remodeling|up-regulation of neuronal remodeling|up-regulation of axon pruning http://purl.obolibrary.org/obo/GO_1904801 GO:1904800 biolink:BiologicalProcess negative regulation of neuron remodeling Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling. go-plus.json downregulation of neuron remodeling|negative regulation of axon pruning|down-regulation of axon pruning|down regulation of neuronal remodeling|down-regulation of neuron remodeling|downregulation of neuronal remodeling|downregulation of axon pruning|inhibition of neuron remodeling|down regulation of axon pruning|negative regulation of neuronal remodeling|down-regulation of neuronal remodeling|inhibition of axon pruning|inhibition of neuronal remodeling|down regulation of neuron remodeling http://purl.obolibrary.org/obo/GO_1904800 CHEBI:64593 biolink:ChemicalSubstance lysophosphatidylcholine O-16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64593 chebi_ph7_3 NCBITaxon:3814 biolink:OrganismalEntity Papilionoideae go-plus.json Faboideae http://purl.obolibrary.org/obo/NCBITaxon_3814 CHEBI:64599 biolink:ChemicalSubstance 4-amino-3-isothiazolidinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64599 CHEBI:64598 biolink:ChemicalSubstance 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_64598 CHEBI:64596 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64596 CHEBI:132177 biolink:ChemicalSubstance 2-hydroxy-3-methyl-2-butenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132177 CHEBI:132174 biolink:ChemicalSubstance beta-D-glucosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132174 chebi_ph7_3 GO:1904819 biolink:BiologicalProcess parietal peritoneum development The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. go-plus.json peritoneal cavity lining development http://purl.obolibrary.org/obo/GO_1904819 GO:1904818 biolink:BiologicalProcess visceral peritoneum development The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_1904818 GO:1904817 biolink:BiologicalProcess serous membrane development The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. go-plus.json serosa development|wall of serous sac development|tunica serosa development http://purl.obolibrary.org/obo/GO_1904817 GO:1904816 biolink:BiologicalProcess positive regulation of protein localization to chromosome, telomeric region Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region. go-plus.json positive regulation of protein localization to telomere|up regulation of protein localization to chromosome, telomeric region|up regulation of protein localization to telomere|upregulation of protein localisation to chromosome, telomeric region|upregulation of protein localization to chromosome, telomeric region|upregulation of protein localization to telomere|activation of protein localisation to chromosome, telomeric region|up-regulation of protein localisation to chromosome, telomeric region|up-regulation of protein localization to chromosome, telomeric region|activation of protein localization to chromosome, telomeric region|up-regulation of protein localization to telomere|activation of protein localization to telomere|positive regulation of protein localisation to chromosome, telomeric region|up regulation of protein localisation to chromosome, telomeric region http://purl.obolibrary.org/obo/GO_1904816 GO:1904815 biolink:BiologicalProcess negative regulation of protein localization to chromosome, telomeric region Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region. go-plus.json down regulation of protein localisation to chromosome, telomeric region|inhibition of protein localisation to chromosome, telomeric region|downregulation of protein localization to chromosome, telomeric region|downregulation of protein localization to telomere|down regulation of protein localization to chromosome, telomeric region|down regulation of protein localization to telomere|inhibition of protein localization to chromosome, telomeric region|inhibition of protein localization to telomere|negative regulation of protein localisation to chromosome, telomeric region|down-regulation of protein localisation to chromosome, telomeric region|down-regulation of protein localization to chromosome, telomeric region|down-regulation of protein localization to telomere|negative regulation of protein localization to telomere|downregulation of protein localisation to chromosome, telomeric region http://purl.obolibrary.org/obo/GO_1904815 GO:1904814 biolink:BiologicalProcess regulation of protein localization to chromosome, telomeric region Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region. go-plus.json regulation of protein localisation to chromosome, telomeric region|regulation of protein localization to telomere http://purl.obolibrary.org/obo/GO_1904814 GO:1904813 biolink:CellularComponent ficolin-1-rich granule lumen Any membrane-enclosed lumen that is part of a ficolin-1-rich granule. go-plus.json membrane-enclosed lumen of ficolin-1 rich granule|membrane-enclosed lumen of ficolin granule|ficolin-1-rich granule membrane-enclosed lumen|membrane-enclosed lumen of ficolin-1-rich granule http://purl.obolibrary.org/obo/GO_1904813 GO:1904812 biolink:BiologicalProcess rRNA acetylation involved in maturation of SSU-rRNA Any rRNA acetylation that is involved in maturation of SSU-rRNA. go-plus.json rRNA acetylation involved in SSU-rRNA maturation|rRNA acetylation involved in processing of 20S pre-rRNA http://purl.obolibrary.org/obo/GO_1904812 GO:1904811 biolink:BiologicalProcess positive regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of dense core granule transport. go-plus.json upregulation of dense core vesicle transport|upregulation of dense core granule transport|up-regulation of dense core vesicle transport|up-regulation of dense core granule transport|activation of dense core vesicle transport|activation of dense core granule transport|positive regulation of dense core vesicle transport|up regulation of dense core vesicle transport|up regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904811 GO:1904810 biolink:BiologicalProcess negative regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport. go-plus.json downregulation of dense core granule transport|down regulation of dense core vesicle transport|down regulation of dense core granule transport|inhibition of dense core vesicle transport|inhibition of dense core granule transport|down-regulation of dense core vesicle transport|negative regulation of dense core vesicle transport|down-regulation of dense core granule transport|downregulation of dense core vesicle transport http://purl.obolibrary.org/obo/GO_1904810 CHEBI:132149 biolink:ChemicalSubstance prostaglandin D3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132149 chebi_ph7_3 CHEBI:132142 biolink:ChemicalSubstance 1,4-naphthoquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_132142 GO:1904829 biolink:BiologicalProcess regulation of aortic smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1904829 GO:1904828 biolink:BiologicalProcess positive regulation of hydrogen sulfide biosynthetic process Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process. go-plus.json up regulation of hydrogen sulfide biosynthesis|up regulation of hydrogen sulfide biosynthetic process|activation of hydrogen sulfide biosynthesis|activation of hydrogen sulfide biosynthetic process|up-regulation of hydrogen sulfide formation|activation of hydrogen sulfide formation|positive regulation of hydrogen sulfide biosynthesis|positive regulation of hydrogen sulfide anabolism|positive regulation of hydrogen sulphide biosynthetic process|positive regulation of hydrogen sulphide biosynthesis|up regulation of hydrogen sulfide anabolism|up regulation of hydrogen sulphide biosynthesis|positive regulation of hydrogen sulfide synthesis|up regulation of hydrogen sulphide biosynthetic process|up regulation of hydrogen sulfide synthesis|positive regulation of hydrogen sulfide formation|up-regulation of hydrogen sulfide biosynthesis|up-regulation of hydrogen sulfide biosynthetic process|up regulation of hydrogen sulfide formation|upregulation of hydrogen sulfide anabolism|upregulation of hydrogen sulphide biosynthesis|upregulation of hydrogen sulphide biosynthetic process|upregulation of hydrogen sulfide biosynthetic process|upregulation of hydrogen sulfide biosynthesis|upregulation of hydrogen sulfide synthesis|upregulation of hydrogen sulfide formation|up-regulation of hydrogen sulfide anabolism|activation of hydrogen sulfide anabolism|activation of hydrogen sulphide biosynthesis|up-regulation of hydrogen sulphide biosynthetic process|up-regulation of hydrogen sulphide biosynthesis|activation of hydrogen sulphide biosynthetic process|up-regulation of hydrogen sulfide synthesis|activation of hydrogen sulfide synthesis http://purl.obolibrary.org/obo/GO_1904828 GO:1904827 biolink:BiologicalProcess negative regulation of hydrogen sulfide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process. go-plus.json negative regulation of hydrogen sulfide anabolism|down-regulation of hydrogen sulfide anabolism|negative regulation of hydrogen sulphide biosynthesis|down-regulation of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulphide biosynthesis|negative regulation of hydrogen sulphide biosynthetic process|negative regulation of hydrogen sulfide biosynthesis|down-regulation of hydrogen sulfide biosynthetic process|down-regulation of hydrogen sulfide biosynthesis|negative regulation of hydrogen sulfide synthesis|down-regulation of hydrogen sulfide synthesis|negative regulation of hydrogen sulfide formation|down-regulation of hydrogen sulfide formation|downregulation of hydrogen sulfide anabolism|downregulation of hydrogen sulphide biosynthesis|inhibition of hydrogen sulfide biosynthesis|inhibition of hydrogen sulfide biosynthetic process|downregulation of hydrogen sulphide biosynthetic process|down regulation of hydrogen sulfide anabolism|downregulation of hydrogen sulfide synthesis|down regulation of hydrogen sulphide biosynthesis|down regulation of hydrogen sulphide biosynthetic process|inhibition of hydrogen sulfide anabolism|downregulation of hydrogen sulfide formation|inhibition of hydrogen sulphide biosynthesis|down regulation of hydrogen sulfide synthesis|inhibition of hydrogen sulphide biosynthetic process|inhibition of hydrogen sulfide synthesis|down regulation of hydrogen sulfide formation|inhibition of hydrogen sulfide formation|down regulation of hydrogen sulfide biosynthetic process|down regulation of hydrogen sulfide biosynthesis|downregulation of hydrogen sulfide biosynthesis|downregulation of hydrogen sulfide biosynthetic process http://purl.obolibrary.org/obo/GO_1904827 GO:1904826 biolink:BiologicalProcess regulation of hydrogen sulfide biosynthetic process Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process. go-plus.json regulation of hydrogen sulfide anabolism|regulation of hydrogen sulphide biosynthesis|regulation of hydrogen sulphide biosynthetic process|regulation of hydrogen sulfide synthesis|regulation of hydrogen sulfide formation|regulation of hydrogen sulfide biosynthesis http://purl.obolibrary.org/obo/GO_1904826 GO:1904825 biolink:BiologicalProcess protein localization to microtubule plus-end A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end. go-plus.json protein localisation to microtubule plus-end http://purl.obolibrary.org/obo/GO_1904825 GO:1904824 biolink:BiologicalProcess anaphase-promoting complex assembly The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex. go-plus.json cyclosome assembly|anaphase-promoting complex formation|APC assembly|cyclosome formation|anaphase promoting complex assembly|anaphase promoting complex formation http://purl.obolibrary.org/obo/GO_1904824 GO:1904823 biolink:BiologicalProcess purine nucleobase transmembrane transport The process in which a purine nucleobase is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904823 GO:1904822 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904822 GO:1904821 biolink:BiologicalProcess chloroplast disassembly The disaggregation of a chloroplast into its constituent components. go-plus.json chloroplast degradation http://purl.obolibrary.org/obo/GO_1904821 GO:1904820 biolink:BiologicalProcess peritoneum development The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. go-plus.json peritonaeum development http://purl.obolibrary.org/obo/GO_1904820 CHEBI:146781 biolink:ChemicalSubstance mature microcin B18 zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_146781 CHEBI:132155 biolink:ChemicalSubstance hydroxynaphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_132155 CHEBI:132154 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronate] go-plus.json http://purl.obolibrary.org/obo/CHEBI_132154 chebi_ph7_3 CHEBI:132157 biolink:ChemicalSubstance hydroxy-1,4-naphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_132157 NCBITaxon:13792 biolink:OrganismalEntity Mamiellales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_13792 CHEBI:132151 biolink:ChemicalSubstance beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-D-GlcpNAc(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132151 chebi_ph7_3 CHEBI:132153 biolink:ChemicalSubstance hyaluronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132153 chebi_ph7_3 NCBITaxon:3603 biolink:OrganismalEntity Vitis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3603 NCBITaxon:3602 biolink:OrganismalEntity Vitaceae go-plus.json Vitidaceae|grape family http://purl.obolibrary.org/obo/NCBITaxon_3602 CHEBI:15529 biolink:ChemicalSubstance lactoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15529 DDANAT:0000083 biolink:OntologyClass Dictyostelium discoideum single cell organism Cell that is an individual member of the species Dictyostelium discoideum. go-plus.json D. discoideum single cell organism http://purl.obolibrary.org/obo/DDANAT_0000083 CHEBI:15525 biolink:ChemicalSubstance palmitoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15525 DDANAT:0000086 biolink:OntologyClass prespore region Region mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. go-plus.json psp region http://purl.obolibrary.org/obo/DDANAT_0000086 CHEBI:15528 biolink:ChemicalSubstance itaconyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15528 CHEBI:15527 biolink:ChemicalSubstance icosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15527 CHEBI:15522 biolink:ChemicalSubstance formyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15522 CHEBI:15521 biolink:ChemicalSubstance lauroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15521 CHEBI:15524 biolink:ChemicalSubstance glutaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15524 CHEBI:15523 biolink:ChemicalSubstance cis-geranoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15523 CHEBI:15520 biolink:ChemicalSubstance cyclohexa-1,5-diene-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15520 DDANAT:0000066 biolink:OntologyClass inner basal disc of the late culminant Central portion of the basal disc of the late culminant. Composed of stalk cells. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000066 CHEBI:15519 biolink:ChemicalSubstance choloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15519 DDANAT:0000065 biolink:OntologyClass basal disc of the late culminant Conical-shaped structure of the late culminant that anchors the stalk to the substratum. Composed of anterior-like cells. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000065 CHEBI:15518 biolink:ChemicalSubstance caffeoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15518 DDANAT:0000068 biolink:OntologyClass stalk of the fruiting body Tubular structure of the fruiting body that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. The stalk of the mature fruiting body is usually 5-15 microns in diameter and between 1.5 to 3 cm in height. go-plus.json sorophore of the fruiting body http://purl.obolibrary.org/obo/DDANAT_0000068 DDANAT:0000073 biolink:OntologyClass basal disc of the fruiting body Conical-shaped structure of the fruiting body that anchors the stalk to the substratum, around 150 to 400 microns in diameter. Composed of anterior-like cells. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000073 CHEBI:15515 biolink:ChemicalSubstance benzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15515 CHEBI:15514 biolink:ChemicalSubstance arachidonoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15514 CHEBI:15517 biolink:ChemicalSubstance butyryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15517 CHEBI:15516 biolink:ChemicalSubstance biotinyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15516 DDANAT:0000074 biolink:OntologyClass inner basal disc of the fruiting body Central portion of the basal disc of the fruiting body composed of stalk cells. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000074 CHEBI:15511 biolink:ChemicalSubstance trans-feruloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15511 CHEBI:15510 biolink:ChemicalSubstance 5-hydroxy-2-furoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15510 CHEBI:15513 biolink:ChemicalSubstance acryloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15513 DDANAT:0000070 biolink:OntologyClass sorus of the fruiting body Structure of the fruiting body supported by the stalk and that contains the spores. The sorus is 125-300 microns in diameter, lemon-shaped, and grayish white to pale yellow in color. go-plus.json spore head of the fruiting body http://purl.obolibrary.org/obo/DDANAT_0000070 CHEBI:15512 biolink:ChemicalSubstance L-3-aminobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15512 DDANAT:0000059 biolink:OntologyClass stalk of the late culminant Tubular structure of the late culminant that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. go-plus.json sorophore of the late culminant http://purl.obolibrary.org/obo/DDANAT_0000059 DDANAT:0000054 biolink:OntologyClass prespore region of the mid culminant Region of the mid culminant mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. go-plus.json psp region of the mid culminant http://purl.obolibrary.org/obo/DDANAT_0000054 DDANAT:0000057 biolink:OntologyClass basal disc of the mid culminant Region located of the mid culminant located closest to the substratum and composed of pst cells (rearguard cells). go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000057 CHEBI:15548 biolink:ChemicalSubstance 15-dehydro-prostaglandin E1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15548 DDANAT:0000061 biolink:OntologyClass sorus of the late culminant Ovoid structure of the late culminant supported by the stalk and that contains the spores. go-plus.json spore head of the late culminant http://purl.obolibrary.org/obo/DDANAT_0000061 CHEBI:15547 biolink:ChemicalSubstance 15-dehydro-prostaglandin E2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15547 CHEBI:15544 biolink:ChemicalSubstance prostaglandin E1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15544 CHEBI:15543 biolink:ChemicalSubstance vinylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15543 CHEBI:15546 biolink:ChemicalSubstance prostaglandin C1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15546 CHEBI:15545 biolink:ChemicalSubstance prostaglandin A1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15545 CHEBI:15540 biolink:ChemicalSubstance sinapoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15540 CHEBI:15542 biolink:ChemicalSubstance thiophene-2-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15542 CHEBI:15541 biolink:ChemicalSubstance stearoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15541 DDANAT:0000048 biolink:OntologyClass prestalk region of the mid culminant The prestalk region of the mid culminant is located at the most apical part of the organism. It consists of about one quarter of the cells. go-plus.json pst region of the mid culminant http://purl.obolibrary.org/obo/DDANAT_0000048 DDANAT:0000049 biolink:OntologyClass prestalk A region of the mid culminant Anterior-most region of the prestalk zone of the mid culminant characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). go-plus.json pstA region of the mid culminant http://purl.obolibrary.org/obo/DDANAT_0000049 DDANAT:0000045 biolink:OntologyClass basal region of the early culminant Region of the early culminant located at the closest to the substratum composed of pstB cells that originated from rearguard cells. go-plus.json base of the early culminant http://purl.obolibrary.org/obo/DDANAT_0000045 DDANAT:0000051 biolink:OntologyClass prestalk AB core region of the mid culminant Cone-shaped area of the prestalk zone of the mid culminant that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. go-plus.json prestalk AB region of the mid culminant|pstAB region of the mid culminant http://purl.obolibrary.org/obo/DDANAT_0000051 CHEBI:15537 biolink:ChemicalSubstance phenylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15537 CHEBI:15536 biolink:ChemicalSubstance pentanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15536 CHEBI:15539 biolink:ChemicalSubstance propionyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15539 DDANAT:0000052 biolink:OntologyClass stalk of the mid culminant Tubular structure of the mid culminant that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. go-plus.json sorophore of the mid culminant http://purl.obolibrary.org/obo/DDANAT_0000052 CHEBI:15538 biolink:ChemicalSubstance phytanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15538 CHEBI:15533 biolink:ChemicalSubstance octanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15533 CHEBI:15532 biolink:ChemicalSubstance myristoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15532 CHEBI:15535 biolink:ChemicalSubstance oxalyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15535 CHEBI:15534 biolink:ChemicalSubstance oleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15534 CHEBI:15531 biolink:ChemicalSubstance malonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15531 CHEBI:15530 biolink:ChemicalSubstance linoleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15530 dc:title biolink:OntologyClass title go-plus.json http://purl.org/dc/elements/1.1/title NCBITaxon:3646 biolink:OrganismalEntity Malpighiales go-plus.json Violales|Violanae http://purl.obolibrary.org/obo/NCBITaxon_3646 NCBITaxon:3641 biolink:OrganismalEntity Theobroma cacao go-plus.json chocolate|cacao|cocoa http://purl.obolibrary.org/obo/NCBITaxon_3641 NCBITaxon:3640 biolink:OrganismalEntity Theobroma go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3640 DDANAT:0000037 biolink:OntologyClass prestalk region of the early culminant The prestalk region of the early culminant is located at the most apical part of the organism. It consists of about one quarter of the cells. go-plus.json pst region of the early culminant http://purl.obolibrary.org/obo/DDANAT_0000037 DDANAT:0000038 biolink:OntologyClass prestalk A region of the early culminant Anterior-most region of the prestalk zone of the early culminant characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). go-plus.json pstA region of the early culminant http://purl.obolibrary.org/obo/DDANAT_0000038 DDANAT:0000033 biolink:OntologyClass prespore region of the migratory slug Region of the migratory slug composed mostly of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. go-plus.json psp region of the migratory slug http://purl.obolibrary.org/obo/DDANAT_0000033 DDANAT:0000032 biolink:OntologyClass prestalk AB core region of the migratory slug Cone-shaped area of the prestalk zone of the migratory slug that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. go-plus.json prestalk AB region of the migratory slug|pstAB region of the migratory slug http://purl.obolibrary.org/obo/DDANAT_0000032 DDANAT:0000040 biolink:OntologyClass prestalk AB core region of the early culminant Cone-shaped area of the prestalk zone of the early culminant that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. go-plus.json prestalk AB region of the early culminant|pstAB region of the early culminant http://purl.obolibrary.org/obo/DDANAT_0000040 CHEBI:64504 biolink:ChemicalSubstance phosphatidylcholine 36:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64504 chebi_ph7_3 CHEBI:64503 biolink:ChemicalSubstance nonadec-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64503 chebi_ph7_3 CHEBI:64502 biolink:ChemicalSubstance 1-heptadecene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64502 chebi_ph7_3 DDANAT:0000041 biolink:OntologyClass prespore region of the early culminant Region of the early culminant mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. go-plus.json psp region of the early culminant http://purl.obolibrary.org/obo/DDANAT_0000041 CHEBI:64508 biolink:ChemicalSubstance 17-methylnonadec-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64508 chebi_ph7_3 CHEBI:64507 biolink:ChemicalSubstance 18-methylnonadec-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64507 chebi_ph7_3 CHEBI:64506 biolink:ChemicalSubstance (Z)-nonadeca-1,14-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64506 chebi_ph7_3 NCBITaxon:3650 biolink:OrganismalEntity Cucurbitaceae go-plus.json cucumber family http://purl.obolibrary.org/obo/NCBITaxon_3650 CHEBI:64509 biolink:ChemicalSubstance oxapenam go-plus.json http://purl.obolibrary.org/obo/CHEBI_64509 chebi_ph7_3 NCBITaxon:3655 biolink:OrganismalEntity Cucumis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3655 DDANAT:0000025 biolink:OntologyClass basal region of the standing slug Region of the standing slug in contact with the substratum and composed of prestalk B cells. go-plus.json base of the standing slug http://purl.obolibrary.org/obo/DDANAT_0000025 DDANAT:0000028 biolink:OntologyClass prestalk region of the migratory slug The prestalk region of the migratory slug is located at the anterior of the organism. It consists of about one quarter of the cells. go-plus.json pst region of the migratory slug|anterior region of the migratory slug http://purl.obolibrary.org/obo/DDANAT_0000028 DDANAT:0000021 biolink:OntologyClass prestalk A region of the standing slug Most apical region of the prestalk zone of the standing slug characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). go-plus.json pstA region of the standing slug http://purl.obolibrary.org/obo/DDANAT_0000021 NCBITaxon:3659 biolink:OrganismalEntity Cucumis sativus go-plus.json cucumbers|cucumber http://purl.obolibrary.org/obo/NCBITaxon_3659 CHEBI:64510 biolink:ChemicalSubstance carbapenam go-plus.json http://purl.obolibrary.org/obo/CHEBI_64510 DDANAT:0000024 biolink:OntologyClass prespore region of the standing slug Region of the standing slug mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. go-plus.json psp region of the standing slug http://purl.obolibrary.org/obo/DDANAT_0000024 DDANAT:0000023 biolink:OntologyClass prestalk AB core region of the standing slug Cone-shaped area of the prestalk zone of the standing slug that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. go-plus.json pstAB region|prestalk AB region of the standing slug http://purl.obolibrary.org/obo/DDANAT_0000023 CHEBI:64515 biolink:ChemicalSubstance pyranoxanthene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64515 CHEBI:64514 biolink:ChemicalSubstance sarcinapterin(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64514 chebi_ph7_3 DDANAT:0000030 biolink:OntologyClass prestalk A region of the migratory slug Anterior-most region of the prestalk zone of the migratory slug and characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). go-plus.json pstAO region of the migratory slug|pstA region of the migratory slug|prestalk AO region of the migratory slug http://purl.obolibrary.org/obo/DDANAT_0000030 CHEBI:64512 biolink:ChemicalSubstance emericellin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64512 chebi_ph7_3 CHEBI:64519 biolink:ChemicalSubstance phosphatidylcholine 38:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64519 chebi_ph7_3 CHEBI:64518 biolink:ChemicalSubstance cordyol C go-plus.json http://purl.obolibrary.org/obo/CHEBI_64518 chebi_ph7_3 CHEBI:64517 biolink:ChemicalSubstance phosphatidylcholine 34:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64517 chebi_ph7_3 CHEBI:64516 biolink:ChemicalSubstance phosphatidylcholine 34:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64516 chebi_ph7_3 DDANAT:0000019 biolink:OntologyClass prestalk region of the standing slug Elongated protrusion of the standing slug located on top of the cell mass that contains pstA cells flanked by pstO cells (expressing ecmA from the proximal and the distal part of its promoter, respectively). go-plus.json pst region of the standing slug http://purl.obolibrary.org/obo/DDANAT_0000019 DDANAT:0000017 biolink:OntologyClass prespore region of the tipped mound Region of the tipped mound mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. go-plus.json psp region of the tipped mound http://purl.obolibrary.org/obo/DDANAT_0000017 DDANAT:0000016 biolink:OntologyClass prestalk region of the tipped mound Elongated protusion of the tipped mound located on top of the cell mass that contains pstA cells flanked by pstO cells (expressing ecmA from the proximal and the distal part of its promoter, respectively). go-plus.json apical tip of the tipped mound|pst region of the tipped mound http://purl.obolibrary.org/obo/DDANAT_0000016 DDANAT:0000011 biolink:OntologyClass late culminant Structure in which stalk tube formation has progressed down to the basal disc. The sorogen ascents up the stalk to it apical position during this stage. Terminal differentiation occurs at this stage: death of the stalk cells and encapsulation of the spores. go-plus.json pseudoplasmodium|culminant http://purl.obolibrary.org/obo/DDANAT_0000011 CHEBI:15508 biolink:ChemicalSubstance gamma-linolenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15508 CHEBI:64522 biolink:ChemicalSubstance averantin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64522 DDANAT:0000010 biolink:OntologyClass mid culminant Structure in which stalk tube formation has progressed down the prespore zone. Basal disc formation begins at this stage, with the migration of pstA and pstB cells to the lower part of the culminant to form the basal disc. go-plus.json pseudoplasmodium|culminant http://purl.obolibrary.org/obo/DDANAT_0000010 CHEBI:15507 biolink:ChemicalSubstance beta-alanyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15507 DDANAT:0000013 biolink:OntologyClass stream Macroscopic appearance of groups of chemotactic cells orienting themselves in a head to tail fashion as they are migrating in the direction of the chemotactic stimulus to form aggregates. go-plus.json pseudoplasmodial stream http://purl.obolibrary.org/obo/DDANAT_0000013 NCBITaxon:3629 biolink:OrganismalEntity Malvaceae go-plus.json mallow family http://purl.obolibrary.org/obo/NCBITaxon_3629 CHEBI:64520 biolink:ChemicalSubstance phosphatidylcholine 36:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64520 chebi_ph7_3 DDANAT:0000012 biolink:OntologyClass fruiting body Dicty asexual organism which is terminally differentiated and consists of a long stalk on top of which sits the sorus that contains spores. The mature fruiting body measures between 1.5 to 3 mm in height. go-plus.json sorocarp http://purl.obolibrary.org/obo/DDANAT_0000012 CHEBI:15509 biolink:ChemicalSubstance 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15509 CHEBI:64526 biolink:ChemicalSubstance phosphatidylcholine 38:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64526 chebi_ph7_3 CHEBI:15504 biolink:ChemicalSubstance pimeloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15504 CHEBI:15503 biolink:ChemicalSubstance 2,3-didehydropimeloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15503 CHEBI:64525 biolink:ChemicalSubstance phosphatidylcholine 38:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64525 chebi_ph7_3 CHEBI:64523 biolink:ChemicalSubstance phosphatidylcholine 36:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64523 chebi_ph7_3 CHEBI:15505 biolink:ChemicalSubstance 6-hydroxycyclohex-1-ene-1-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15505 CHEBI:15500 biolink:ChemicalSubstance 4-hydroxybenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15500 CHEBI:15502 biolink:ChemicalSubstance 5-hydroxythiophene-2-carbonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15502 CHEBI:15501 biolink:ChemicalSubstance 5-hydroxypentanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15501 NCBITaxon:3633 biolink:OrganismalEntity Gossypium go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3633 NCBITaxon:3635 biolink:OrganismalEntity Gossypium hirsutum go-plus.json Gossypium hirsutum subsp. mexicanum|Gossypium purpurascens|cotton|American cotton|American upland cotton|Gossypium lanceolatum http://purl.obolibrary.org/obo/NCBITaxon_3635 DDANAT:0000008 biolink:OntologyClass migratory slug When the conditions are not optimal for the completion of development, the standing slug bends from a vertical position to a horizontal position, producing a migratory that slug has the ability to migrate towards more favorable environmental conditions. The slug is cylindrical in shape with a rounded, tapering region at its anterior end that is raised with respect to the substratum. It usually measures between 0.8 to 1.2 mm in length with a diameter of 0.15 to 0.25 mm. Slugs sense and respond to light, temperature and acidity, and do not enter culmination until the conditions are optimal. The slug can move at a speed of 0.5 to 2 mm per hour. A trail of slime is deposited on the surface during migration. go-plus.json pseudoplasmodium http://purl.obolibrary.org/obo/DDANAT_0000008 DDANAT:0000007 biolink:OntologyClass standing slug Cylindrical structure that is formed by elongation of the mound under the control of the tip. The elongating tip is called the first finger. go-plus.json finger|pseudoplasmodium|first finger http://purl.obolibrary.org/obo/DDANAT_0000007 DDANAT:0000009 biolink:OntologyClass early culminant Structure formed after the arrest of slug migration formed when cells of the posterior region of the slug move under the tip. Stalk tube formation is initiated at this stage. go-plus.json mexican hat|culminant|pseudoplasmodium http://purl.obolibrary.org/obo/DDANAT_0000009 DDANAT:0000004 biolink:OntologyClass loose aggregate First adherent mass of cells observed during development, relatively flat with indistinct borders. go-plus.json loose mound http://purl.obolibrary.org/obo/DDANAT_0000004 DDANAT:0000003 biolink:OntologyClass aggregation territory Area covered by a group of chemotactic cells converging toward the same aggregation center. Can reach a diameter of up to 1 cm. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000003 DDANAT:0000006 biolink:OntologyClass tipped mound Hemispherical structure composed of post-aggregative cells that are undergoing differentiation and that have formed a tip. go-plus.json tipped aggregate|pseudoplasmodium http://purl.obolibrary.org/obo/DDANAT_0000006 DDANAT:0000005 biolink:OntologyClass mound Hemispherical structure composed of post-aggregative cells that are undergoing differentiation. go-plus.json tight mound|pseudoplasmodium|tight aggregate http://purl.obolibrary.org/obo/DDANAT_0000005 CHEBI:64532 biolink:ChemicalSubstance dihydroxytoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64532 CHEBI:64531 biolink:ChemicalSubstance fumitremorgin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_64531 chebi_ph7_3 CHEBI:64530 biolink:ChemicalSubstance brevianamide F go-plus.json http://purl.obolibrary.org/obo/CHEBI_64530 chebi_ph7_3 CHEBI:64535 biolink:ChemicalSubstance pseurotin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64535 chebi_ph7_3 CHEBI:64534 biolink:ChemicalSubstance terrequinone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64534 NCBITaxon:3689 biolink:OrganismalEntity Populus go-plus.json poplar|poplars|poplar trees http://purl.obolibrary.org/obo/NCBITaxon_3689 NCBITaxon:3688 biolink:OrganismalEntity Salicaceae go-plus.json willow family|Flacourtiaceae http://purl.obolibrary.org/obo/NCBITaxon_3688 GO:1904799 biolink:BiologicalProcess regulation of neuron remodeling Any process that modulates the frequency, rate or extent of neuron remodeling. go-plus.json regulation of neuronal remodeling|regulation of axon pruning http://purl.obolibrary.org/obo/GO_1904799 GO:1904798 biolink:BiologicalProcess positive regulation of core promoter binding Any process that activates or increases the frequency, rate or extent of core promoter binding. go-plus.json up-regulation of core promoter binding|upregulation of core promoter binding|up regulation of core promoter binding|activation of core promoter binding http://purl.obolibrary.org/obo/GO_1904798 GO:1904797 biolink:BiologicalProcess negative regulation of core promoter binding Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding. go-plus.json inhibition of core promoter binding|down regulation of core promoter binding|downregulation of core promoter binding|down-regulation of core promoter binding http://purl.obolibrary.org/obo/GO_1904797 GO:1904796 biolink:BiologicalProcess regulation of core promoter binding Any process that modulates the frequency, rate or extent of core promoter binding. go-plus.json http://purl.obolibrary.org/obo/GO_1904796 GO:1904795 biolink:BiologicalProcess positive regulation of euchromatin binding Any process that activates or increases the frequency, rate or extent of euchromatin binding. go-plus.json upregulation of euchromatin binding|up regulation of euchromatin binding|activation of euchromatin binding|up-regulation of euchromatin binding http://purl.obolibrary.org/obo/GO_1904795 CHEBI:39573 biolink:ChemicalSubstance (13R)-HPODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_39573 NCBITaxon:3694 biolink:OrganismalEntity Populus trichocarpa go-plus.json western balsam poplar|Populus balsamifera subsp. trichocarpa|black cottonwood http://purl.obolibrary.org/obo/NCBITaxon_3694 NCBITaxon:3699 biolink:OrganismalEntity Brassicales go-plus.json Capparales http://purl.obolibrary.org/obo/NCBITaxon_3699 CHEBI:15599 biolink:ChemicalSubstance cis-3-phenylcyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15599 CHEBI:15598 biolink:ChemicalSubstance 2-methylcitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15598 chebi_ph7_3 CHEBI:15595 biolink:ChemicalSubstance malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15595 chebi_ph7_3 CHEBI:15594 biolink:ChemicalSubstance 3-propylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15594 chebi_ph7_3 CHEBI:15597 biolink:ChemicalSubstance (2R)-2-O-phosphonato-3-sulfonatolactate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15597 chebi_ph7_3 NCBITaxon:2493110 biolink:OrganismalEntity Trichoplacidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2493110 CHEBI:15596 biolink:ChemicalSubstance sinapic acid (S)-malate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_15596 CHEBI:15591 biolink:ChemicalSubstance 3-ethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15591 CHEBI:15590 biolink:ChemicalSubstance 2,3-dimethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15590 CHEBI:15593 biolink:ChemicalSubstance 3-oxalomalate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15593 chebi_ph7_3 CHEBI:15592 biolink:ChemicalSubstance 3-isopropylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15592 chebi_ph7_3 CHEBI:327995 biolink:ChemicalSubstance tyraminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_327995 chebi_ph7_3 CHEBI:39567 biolink:ChemicalSubstance 12-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39567 CHEBI:39564 biolink:ChemicalSubstance (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39564 CHEBI:15569 biolink:ChemicalSubstance N-(carboxyaminomethyl)urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_15569 CHEBI:40538 biolink:ChemicalSubstance benzylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_40538 CHEBI:15566 biolink:ChemicalSubstance (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15566 CHEBI:15565 biolink:ChemicalSubstance (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15565 chebi_ph7_3 CHEBI:15568 biolink:ChemicalSubstance (R)-2-halocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15568 CHEBI:15567 biolink:ChemicalSubstance (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15567 CHEBI:8113 biolink:ChemicalSubstance phlorizin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8113 chebi_ph7_3 CHEBI:15562 biolink:ChemicalSubstance D-threo-isocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15562 chebi_ph7_3 CHEBI:15561 biolink:ChemicalSubstance cis-1,2-dihydronaphthalene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15561 CHEBI:15564 biolink:ChemicalSubstance (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15564 CHEBI:15563 biolink:ChemicalSubstance D-erythro-isocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15563 chebi_ph7_3 CHEBI:8116 biolink:ChemicalSubstance phorbol go-plus.json http://purl.obolibrary.org/obo/CHEBI_8116 chebi_ph7_3 CHEBI:15560 biolink:ChemicalSubstance (15Z)-12-oxophyto-10,15-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15560 CHEBI:15559 biolink:ChemicalSubstance 15-oxo-ETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15559 CHEBI:15558 biolink:ChemicalSubstance 15(S)-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_15558 CHEBI:39547 biolink:ChemicalSubstance (R)-carnitinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_39547 CHEBI:15555 biolink:ChemicalSubstance prostaglandin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15555 CHEBI:15554 biolink:ChemicalSubstance prostaglandin H2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15554 CHEBI:15557 biolink:ChemicalSubstance 15-dehydro-prostaglandin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15557 CHEBI:15556 biolink:ChemicalSubstance 15-dehydro-prostaglandin I2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15556 CHEBI:15551 biolink:ChemicalSubstance prostaglandin E2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15551 CHEBI:15550 biolink:ChemicalSubstance 13,14-dihydro-15-oxo-prostaglandin E2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15550 CHEBI:15553 biolink:ChemicalSubstance prostaglandin F2alpha go-plus.json http://purl.obolibrary.org/obo/CHEBI_15553 CHEBI:15552 biolink:ChemicalSubstance prostaglandin I2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_15552 CHEBI:15588 biolink:ChemicalSubstance (R)-malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15588 chebi_ph7_3 CHEBI:15587 biolink:ChemicalSubstance (R)-3,3-dimethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15587 CHEBI:15589 biolink:ChemicalSubstance (S)-malate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15589 chebi_ph7_3 CHEBI:15584 biolink:ChemicalSubstance citramalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15584 CHEBI:15583 biolink:ChemicalSubstance (R)-2-ethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15583 CHEBI:15586 biolink:ChemicalSubstance D-citramalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15586 CHEBI:40519 biolink:ChemicalSubstance adamantane go-plus.json http://purl.obolibrary.org/obo/CHEBI_40519 chebi_ph7_3 CHEBI:15580 biolink:ChemicalSubstance (2E,6E,10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15580 CHEBI:15582 biolink:ChemicalSubstance (2R,3S)-2,3-dimethylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15582 CHEBI:15581 biolink:ChemicalSubstance juvenile hormone II go-plus.json http://purl.obolibrary.org/obo/CHEBI_15581 chebi_ph7_3 CHEBI:8108 biolink:ChemicalSubstance pheophytin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8108 CHEBI:15577 biolink:ChemicalSubstance (3beta,24R,24'R)-fucosterol epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15577 chebi_ph7_3 CHEBI:15576 biolink:ChemicalSubstance (24R)-24-methylcycloart-25-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15576 chebi_ph7_3 CHEBI:15579 biolink:ChemicalSubstance (25S)-5beta-spirostan-3beta-yl beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_15579 chebi_ph7_3 CHEBI:15578 biolink:ChemicalSubstance (25S)-5beta-spirostan-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15578 chebi_ph7_3 CHEBI:15573 biolink:ChemicalSubstance (2-aminoethyl)phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15573 CHEBI:15572 biolink:ChemicalSubstance 2,3-dihydroxybenzoyl 5'-adenylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15572 CHEBI:8100 biolink:ChemicalSubstance 3-phenyllactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_8100 chebi_ph7_3 CHEBI:15575 biolink:ChemicalSubstance nuatigenin 3-beta-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_15575 chebi_ph7_3 CHEBI:15574 biolink:ChemicalSubstance nuatigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15574 chebi_ph7_3 CHEBI:15571 biolink:ChemicalSubstance hydrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15571 chebi_ph7_3 CHEBI:15570 biolink:ChemicalSubstance D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15570 GO:1904719 biolink:BiologicalProcess positive regulation of AMPA glutamate receptor clustering Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering. go-plus.json up regulation of AMPA glutamate receptor clustering|positive regulation of AMPA receptor clustering|up regulation of AMPA receptor clustering|up regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|upregulation of AMPA glutamate receptor clustering|upregulation of AMPA receptor clustering|up-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|up-regulation of AMPA glutamate receptor clustering|activation of AMPA glutamate receptor clustering|up-regulation of AMPA receptor clustering|activation of AMPA receptor clustering|upregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering http://purl.obolibrary.org/obo/GO_1904719 GO:1904718 biolink:BiologicalProcess negative regulation of AMPA glutamate receptor clustering Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering. go-plus.json downregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|downregulation of AMPA glutamate receptor clustering|downregulation of AMPA receptor clustering|down regulation of AMPA glutamate receptor clustering|inhibition of AMPA glutamate receptor clustering|down regulation of AMPA receptor clustering|inhibition of AMPA receptor clustering|negative regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|inhibition of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of AMPA glutamate receptor clustering|down-regulation of AMPA receptor clustering|negative regulation of AMPA receptor clustering|down regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering http://purl.obolibrary.org/obo/GO_1904718 GO:1904717 biolink:BiologicalProcess regulation of AMPA glutamate receptor clustering Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering. go-plus.json regulation of AMPA receptor clustering|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering http://purl.obolibrary.org/obo/GO_1904717 GO:1904716 biolink:BiologicalProcess positive regulation of chaperone-mediated autophagy Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy. go-plus.json up regulation of chaperone-mediated autophagy|up regulation of CMA|positive regulation of CMA|activation of CMA|upregulation of chaperone-mediated autophagy|up-regulation of CMA|up-regulation of chaperone-mediated autophagy|activation of chaperone-mediated autophagy|upregulation of CMA http://purl.obolibrary.org/obo/GO_1904716 GO:1904715 biolink:BiologicalProcess negative regulation of chaperone-mediated autophagy Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy. go-plus.json down-regulation of chaperone-mediated autophagy|down regulation of CMA|downregulation of CMA|downregulation of chaperone-mediated autophagy|negative regulation of CMA|down regulation of chaperone-mediated autophagy|down-regulation of CMA|inhibition of chaperone-mediated autophagy|inhibition of CMA http://purl.obolibrary.org/obo/GO_1904715 GO:1904714 biolink:BiologicalProcess regulation of chaperone-mediated autophagy Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy. go-plus.json regulation of CMA http://purl.obolibrary.org/obo/GO_1904714 GO:1904713 biolink:MolecularActivity beta-catenin destruction complex binding Binding to a beta-catenin destruction complex. go-plus.json 23S APC complex binding|APC-Axin-1-beta-catenin complex binding|BDC binding|Axin-APC-beta-catenin-GSK3B complex binding|beta-catenin degradation complex binding http://purl.obolibrary.org/obo/GO_1904713 GO:1904712 biolink:BiologicalProcess positive regulation of Wnt-Frizzled-LRP5/6 complex assembly Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. go-plus.json upregulation of Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP5 complex assembly|activation of WNT-FZD-LRP6 complex formation|positive regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of WNT-FZD-LRP5 complex formation|up regulation of Frizzled-LRP5/6 complex assembly|up-regulation of WNT-FZD-LRP6 complex assembly|upregulation of Wnt-FZD-LRP5/6 trimeric complex formation|up regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|upregulation of Wnt-induced Frizzled-LRP5/6 complex formation|upregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|positive regulation of WNT-FZD-LRP6 complex formation|positive regulation of Frizzled-LRP5/6 complex assembly|positive regulation of WNT-FZD-LRP5 complex formation|up regulation of WNT-FZD-LRP6 complex formation|up regulation of WNT-FZD-LRP5 complex formation|up regulation of Frizzled-LRP5/6 complex formation|upregulation of WNT-FZD-LRP5 complex assembly|upregulation of WNT-FZD-LRP6 complex assembly|up regulation of Wnt-FZD-LRP5/6 trimeric complex formation|upregulation of Frizzled-LRP5/6 complex assembly|positive regulation of Frizzled-LRP5/6 complex formation|upregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|up regulation of Wnt-induced Frizzled-LRP5/6 complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex formation|activation of Wnt-FZD-LRP5/6 trimeric complex formation|up-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|activation of Wnt-FZD-LRP5/6 trimeric complex assembly|positive regulation of Wnt-induced Frizzled-LRP5/6 complex formation|activation of Frizzled-LRP5/6 complex formation|upregulation of WNT-FZD-LRP6 complex formation|upregulation of WNT-FZD-LRP5 complex formation|up regulation of WNT-FZD-LRP5 complex assembly|up-regulation of Frizzled-LRP5/6 complex assembly|activation of Wnt-induced Frizzled-LRP5/6 complex formation|up regulation of WNT-FZD-LRP6 complex assembly|up-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of Frizzled-LRP5/6 complex assembly|positive regulation of WNT-FZD-LRP5 complex assembly|positive regulation of WNT-FZD-LRP6 complex assembly|up-regulation of Frizzled-LRP5/6 complex formation|up-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|up-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP6 complex formation|up regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|activation of WNT-FZD-LRP5 complex assembly|activation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of WNT-FZD-LRP6 complex assembly|up-regulation of WNT-FZD-LRP5 complex formation http://purl.obolibrary.org/obo/GO_1904712 GO:1904711 biolink:BiologicalProcess regulation of Wnt-Frizzled-LRP5/6 complex assembly Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. go-plus.json regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|regulation of Frizzled-LRP5/6 complex formation|regulation of Wnt receptor complex assembly|regulation of Wnt-FZD-LRP5/6 trimeric complex formation|regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|regulation of Wnt-induced Frizzled-LRP5/6 complex formation|regulation of WNT-FZD-LRP6 complex formation|regulation of Frizzled-LRP5/6 complex assembly|regulation of WNT-FZD-LRP5 complex formation|regulation of WNT-FZD-LRP5 complex assembly|regulation of WNT-FZD-LRP6 complex assembly http://purl.obolibrary.org/obo/GO_1904711 GO:1904710 biolink:BiologicalProcess positive regulation of granulosa cell apoptotic process Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process. go-plus.json up regulation of granulosa cell apoptotic process|up regulation of granulosa cell of ovary apoptotic process|activation of granulosa cell of ovary apoptotic process|activation of granulosa cell of ovary apoptosis|positive regulation of granulosa cell of ovary apoptotic process|upregulation of granulosa cell apoptosis|up-regulation of granulosa cell of ovary apoptosis|upregulation of granulosa cell apoptotic process|up-regulation of granulosa cell of ovary apoptotic process|up-regulation of granulosa cell apoptosis|upregulation of granulosa cell of ovary apoptosis|up-regulation of granulosa cell apoptotic process|activation of granulosa cell apoptosis|activation of granulosa cell apoptotic process|upregulation of granulosa cell of ovary apoptotic process|positive regulation of granulosa cell apoptosis|up regulation of granulosa cell apoptosis|up regulation of granulosa cell of ovary apoptosis|positive regulation of granulosa cell of ovary apoptosis http://purl.obolibrary.org/obo/GO_1904710 CHEBI:132245 biolink:ChemicalSubstance (2R,3S)-glycosmisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132245 CHEBI:132244 biolink:ChemicalSubstance (E)-3-(indol-3-yl)acrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132244 CHEBI:132247 biolink:ChemicalSubstance (-)-DCA-CL go-plus.json http://purl.obolibrary.org/obo/CHEBI_132247 CHEBI:132246 biolink:ChemicalSubstance all-trans-3,4-didehydroretinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132246 chebi_ph7_3 CHEBI:132249 biolink:ChemicalSubstance (-)-DCA-CC go-plus.json http://purl.obolibrary.org/obo/CHEBI_132249 CHEBI:132248 biolink:ChemicalSubstance N(4)-(N-acetyl-beta-D-glucosyl)-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132248 chebi_ph7_3 CHEBI:132240 biolink:ChemicalSubstance ethylenediaminediacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132240 GO:1904729 biolink:BiologicalProcess regulation of intestinal lipid absorption Any process that modulates the frequency, rate or extent of intestinal lipid absorption. go-plus.json http://purl.obolibrary.org/obo/GO_1904729 GO:1904728 biolink:BiologicalProcess positive regulation of replicative senescence Any process that activates or increases the frequency, rate or extent of replicative senescence. go-plus.json up-regulation of replicative senescence|activation of replicative senescence|up regulation of replicative senescence|upregulation of replicative senescence http://purl.obolibrary.org/obo/GO_1904728 GO:1904727 biolink:BiologicalProcess negative regulation of replicative senescence Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence. go-plus.json down-regulation of replicative senescence|downregulation of replicative senescence|down regulation of replicative senescence|inhibition of replicative senescence http://purl.obolibrary.org/obo/GO_1904727 GO:1904726 biolink:BiologicalProcess regulation of replicative senescence Any process that modulates the frequency, rate or extent of replicative senescence. go-plus.json http://purl.obolibrary.org/obo/GO_1904726 GO:1904725 biolink:MolecularActivity obsolete TFIIB-class transcription factor binding involved in negative regulation of transcription OBSOLETE. Any TFIIB-class transcription factor binding that is involved in negative regulation of DNA-templated transcription. go-plus.json TFIIB-class transcription factor binding involved in inhibition of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in downregulation of gene-specific transcription|TFIIB-class transcription factor binding involved in down-regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in down regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in transcription repressor activity|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-templated|TFIIB-class transcription factor binding involved in down regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of cellular transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in down-regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in downregulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in inhibition of gene-specific transcription http://purl.obolibrary.org/obo/GO_1904725 GO:1904724 biolink:CellularComponent tertiary granule lumen Any membrane-enclosed lumen that is part of a tertiary granule. go-plus.json membrane-enclosed lumen of tertiary granule|gelatinase granule membrane-enclosed lumen|membrane-enclosed lumen of gelatinase granule|tertiary granule membrane-enclosed lumen http://purl.obolibrary.org/obo/GO_1904724 GO:1904723 biolink:BiologicalProcess negative regulation of Wnt-Frizzled-LRP5/6 complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. go-plus.json downregulation of WNT-FZD-LRP5 complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex assembly|downregulation of WNT-FZD-LRP6 complex assembly|negative regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|negative regulation of Wnt-induced Frizzled-LRP5/6 complex formation|inhibition of WNT-FZD-LRP6 complex formation|negative regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of WNT-FZD-LRP5 complex formation|inhibition of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of WNT-FZD-LRP5 complex assembly|negative regulation of WNT-FZD-LRP5 complex assembly|negative regulation of WNT-FZD-LRP6 complex assembly|down-regulation of WNT-FZD-LRP6 complex assembly|inhibition of Frizzled-LRP5/6 complex formation|negative regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down-regulation of Frizzled-LRP5/6 complex assembly|down-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|downregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex formation|negative regulation of WNT-FZD-LRP6 complex formation|down-regulation of WNT-FZD-LRP6 complex formation|negative regulation of WNT-FZD-LRP5 complex formation|down regulation of Frizzled-LRP5/6 complex formation|negative regulation of Frizzled-LRP5/6 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down-regulation of WNT-FZD-LRP5 complex formation|inhibition of Wnt-FZD-LRP5/6 trimeric complex assembly|downregulation of Frizzled-LRP5/6 complex assembly|inhibition of WNT-FZD-LRP5 complex assembly|downregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex formation|downregulation of Frizzled-LRP5/6 complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex formation|inhibition of WNT-FZD-LRP6 complex assembly|down regulation of Frizzled-LRP5/6 complex assembly|downregulation of Wnt-FZD-LRP5/6 trimeric complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|inhibition of Frizzled-LRP5/6 complex assembly|downregulation of WNT-FZD-LRP6 complex formation|downregulation of Wnt-induced Frizzled-LRP5/6 complex formation|downregulation of WNT-FZD-LRP5 complex formation|down regulation of WNT-FZD-LRP5 complex assembly|down regulation of WNT-FZD-LRP6 complex assembly|down regulation of WNT-FZD-LRP6 complex formation|down-regulation of Frizzled-LRP5/6 complex formation|down regulation of WNT-FZD-LRP5 complex formation|negative regulation of Frizzled-LRP5/6 complex formation http://purl.obolibrary.org/obo/GO_1904723 GO:1904722 biolink:BiologicalProcess obsolete positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response OBSOLETE. Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. go-plus.json up regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|activation of IRE1-mediated XBP-1 mRNA cleavage|activation of mRNA endonucleolytic cleavage involved in unfolded protein response|up-regulation of XBP1 mRNA cleavage|upregulation of HAC1-type intron splice site recognition and cleavage|up-regulation of HAC1 mRNA cleavage|up-regulation of IRE1-mediated XBP-1 mRNA cleavage|activation of XBP1 mRNA cleavage|up-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|activation of HAC1 mRNA cleavage|up regulation of HAC1-type intron splice site recognition and cleavage|positive regulation of XBP1 mRNA cleavage|up regulation of XBP1 mRNA cleavage|positive regulation of HAC1-type intron splice site recognition and cleavage|upregulation of IRE1-mediated XBP-1 mRNA cleavage|positive regulation of HAC1 mRNA cleavage|up regulation of HAC1 mRNA cleavage|activation of HAC1-type intron splice site recognition and cleavage|upregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|up regulation of IRE1-mediated XBP-1 mRNA cleavage|upregulation of XBP1 mRNA cleavage|up-regulation of HAC1-type intron splice site recognition and cleavage|positive regulation of IRE1-mediated XBP-1 mRNA cleavage|upregulation of HAC1 mRNA cleavage http://purl.obolibrary.org/obo/GO_1904722 GO:1904721 biolink:BiologicalProcess obsolete negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. go-plus.json inhibition of HAC1 mRNA cleavage|down regulation of HAC1-type intron splice site recognition and cleavage|down-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|negative regulation of XBP1 mRNA cleavage|down-regulation of XBP1 mRNA cleavage|downregulation of HAC1-type intron splice site recognition and cleavage|inhibition of IRE1-mediated XBP-1 mRNA cleavage|inhibition of mRNA endonucleolytic cleavage involved in unfolded protein response|down-regulation of HAC1 mRNA cleavage|negative regulation of HAC1 mRNA cleavage|downregulation of XBP1 mRNA cleavage|down regulation of IRE1-mediated XBP-1 mRNA cleavage|down-regulation of HAC1-type intron splice site recognition and cleavage|negative regulation of HAC1-type intron splice site recognition and cleavage|downregulation of HAC1 mRNA cleavage|downregulation of IRE1-mediated XBP-1 mRNA cleavage|down regulation of XBP1 mRNA cleavage|down regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|down regulation of HAC1 mRNA cleavage|inhibition of XBP1 mRNA cleavage|downregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|down-regulation of IRE1-mediated XBP-1 mRNA cleavage|negative regulation of IRE1-mediated XBP-1 mRNA cleavage|inhibition of HAC1-type intron splice site recognition and cleavage http://purl.obolibrary.org/obo/GO_1904721 GO:1904720 biolink:BiologicalProcess obsolete regulation of mRNA endonucleolytic cleavage involved in unfolded protein response OBSOLETE. Any process that modulates the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. go-plus.json regulation of HAC1-type intron splice site recognition and cleavage|regulation of IRE1-mediated XBP-1 mRNA cleavage|regulation of XBP1 mRNA cleavage|regulation of HAC1 mRNA cleavage http://purl.obolibrary.org/obo/GO_1904720 CHEBI:132253 biolink:ChemicalSubstance 12,18-didecarboxysirohaem go-plus.json http://purl.obolibrary.org/obo/CHEBI_132253 CHEBI:132256 biolink:ChemicalSubstance N-arachidonoyl-2-oxoserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_132256 chebi_ph7_3 CHEBI:132255 biolink:ChemicalSubstance N-arachidonoylserotonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_132255 chebi_ph7_3 CHEBI:132258 biolink:ChemicalSubstance (2E,5E)-tetradecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_132258 CHEBI:132257 biolink:ChemicalSubstance (2S,3R)-glycosmisic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132257 CHEBI:132259 biolink:ChemicalSubstance all-trans-4-hydroxyretinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132259 chebi_ph7_3 CHEBI:132250 biolink:ChemicalSubstance (+)-DCA-CC go-plus.json http://purl.obolibrary.org/obo/CHEBI_132250 CHEBI:132251 biolink:ChemicalSubstance (+)-DCA-CL go-plus.json http://purl.obolibrary.org/obo/CHEBI_132251 GO:1904739 biolink:BiologicalProcess regulation of synapse organization by posttranscriptional regulation of gene expression A posttranscriptional regulation of gene expression that results in regulation of synapse organization. go-plus.json regulation of synapse organization and biogenesis by posttranscriptional regulation of gene expression|regulation of synapse development by posttranscriptional regulation of gene expression|regulation of synapse morphogenesis by posttranscriptional regulation of gene expression|regulation of synapse organisation by posttranscriptional regulation of gene expression http://purl.obolibrary.org/obo/GO_1904739 GO:1904738 biolink:BiologicalProcess vascular associated smooth muscle cell migration The orderly movement of a vascular associated smooth muscle cell from one site to another. go-plus.json vascular smooth muscle cell migration http://purl.obolibrary.org/obo/GO_1904738 CHEBI:88494 biolink:ChemicalSubstance epsilon-(gamma-glutamyl)lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88494 GO:1904737 biolink:BiologicalProcess positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. go-plus.json activation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|upregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase http://purl.obolibrary.org/obo/GO_1904737 GO:1904736 biolink:BiologicalProcess negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. go-plus.json down-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|downregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|down regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|inhibition of fatty acid beta-oxidation using acyl-CoA dehydrogenase http://purl.obolibrary.org/obo/GO_1904736 GO:1904735 biolink:BiologicalProcess regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. go-plus.json http://purl.obolibrary.org/obo/GO_1904735 CHEBI:132228 biolink:ChemicalSubstance (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132228 GO:1904734 biolink:BiologicalProcess positive regulation of electron transfer activity Any process that activates or increases the frequency, rate or extent of electron transfer activity. go-plus.json up regulation of rubredoxin|activation of redox-active disulfide bond electron carrier|upregulation of chloroplast-type ferredoxin|activation of electron transporter activity|positive regulation of 2Fe-2S electron transfer carrier|up regulation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of polyferredoxin|upregulation of high-potential iron-sulfur carrier|positive regulation of dicluster bacterial-type ferredoxin|upregulation of amicyanin|up-regulation of bacterial-type ferredoxin|activation of mononuclear iron electron carrier|activation of electron carrier activity|up regulation of 2Fe-2S electron transfer carrier|up regulation of electron transfer flavoprotein, group I|positive regulation of electron transfer flavoprotein, group II|positive regulation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of electron transporter activity|positive regulation of azurin|activation of monocluster bacterial-type ferredoxin|positive regulation of electron transfer flavoprotein, group I|upregulation of electron transfer flavoprotein|upregulation of electron acceptor activity|upregulation of copper electron carrier|up regulation of electron carrier activity|positive regulation of electron transporter activity|up regulation of azurin|up-regulation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of electron transfer flavoprotein, group II|activation of small blue copper electron carrier|positive regulation of redox-active disulfide bond electron carrier|upregulation of adrenodoxin-type ferredoxin|positive regulation of polyferredoxin|activation of dicluster bacterial-type ferredoxin|upregulation of iron-sulfur electron transfer carrier|up regulation of redox-active disulfide bond electron carrier|up-regulation of mononuclear iron electron carrier|up regulation of electron carrier, chlorophyll electron transport system|up regulation of polyferredoxin|activation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of electron donor activity|activation of electron transfer flavoprotein, group I|positive regulation of small blue copper electron carrier|upregulation of bacterial-type ferredoxin|upregulation of rubredoxin|up regulation of chloroplast-type ferredoxin|up-regulation of high-potential iron-sulfur carrier|up-regulation of monocluster bacterial-type ferredoxin|positive regulation of electron carrier, chlorophyll electron transport system|positive regulation of electron donor activity|activation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of amicyanin|up-regulation of dicluster bacterial-type ferredoxin|upregulation of 2Fe-2S electron transfer carrier|up regulation of small blue copper electron carrier|positive regulation of chloroplast-type ferredoxin|positive regulation of amicyanin|up-regulation of electron transfer flavoprotein|up-regulation of electron acceptor activity|up-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of electron carrier, chlorophyll electron transport system|up regulation of copper electron carrier|upregulation of azurin|upregulation of electron transfer flavoprotein, group II|up-regulation of electron transfer flavoprotein, group I|positive regulation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of adrenodoxin-type ferredoxin|activation of electron donor activity|up-regulation of electron transporter activity|activation of high-potential iron-sulfur carrier|upregulation of redox-active disulfide bond electron carrier|activation of chloroplast-type ferredoxin|upregulation of mononuclear iron electron carrier|up regulation of iron-sulfur electron transfer carrier|positive regulation of copper electron carrier|upregulation of polyferredoxin|positive regulation of adrenodoxin-type ferredoxin|up-regulation of electron carrier activity|up regulation of thioredoxin-like 2Fe-2S ferredoxin|activation of amicyanin|activation of electron acceptor activity|positive regulation of iron-sulfur electron transfer carrier|activation of electron transfer flavoprotein|upregulation of monocluster bacterial-type ferredoxin|up-regulation of rubredoxin|up regulation of bacterial-type ferredoxin|positive regulation of high-potential iron-sulfur carrier|up-regulation of 2Fe-2S electron transfer carrier|up-regulation of electron carrier, chlorophyll electron transport system|upregulation of dicluster bacterial-type ferredoxin|positive regulation of bacterial-type ferredoxin|up-regulation of electron donor activity|upregulation of small blue copper electron carrier|activation of copper electron carrier|up-regulation of chloroplast-type ferredoxin|activation of adrenodoxin-type ferredoxin|upregulation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of high-potential iron-sulfur carrier|positive regulation of electron acceptor activity|up-regulation of azurin|up-regulation of electron transfer flavoprotein, group II|activation of iron-sulfur electron transfer carrier|positive regulation of electron transfer flavoprotein|upregulation of electron transfer flavoprotein, group I|up-regulation of amicyanin|upregulation of electron transporter activity|activation of rubredoxin|up-regulation of redox-active disulfide bond electron carrier|up regulation of electron transfer flavoprotein|up regulation of electron acceptor activity|up regulation of mononuclear iron electron carrier|activation of 2Fe-2S electron transfer carrier|activation of bacterial-type ferredoxin|up-regulation of polyferredoxin|upregulation of electron carrier activity|upregulation of thioredoxin-like 2Fe-2S ferredoxin|up-regulation of copper electron carrier|positive regulation of mononuclear iron electron carrier|up regulation of monocluster bacterial-type ferredoxin|up-regulation of adrenodoxin-type ferredoxin|activation of azurin|positive regulation of rubredoxin|upregulation of electron carrier, chlorophyll electron transport system|activation of electron transfer flavoprotein, group II|up-regulation of iron-sulfur electron transfer carrier|up regulation of dicluster bacterial-type ferredoxin|up-regulation of small blue copper electron carrier|upregulation of electron donor activity|positive regulation of monocluster bacterial-type ferredoxin http://purl.obolibrary.org/obo/GO_1904734 GO:1904733 biolink:BiologicalProcess negative regulation of electron transfer activity Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity. go-plus.json negative regulation of redox-active disulfide bond electron carrier|negative regulation of mononuclear iron electron carrier|down regulation of electron acceptor activity|down-regulation of redox-active disulfide bond electron carrier|down-regulation of mononuclear iron electron carrier|down regulation of electron transfer flavoprotein|inhibition of copper electron carrier|down regulation of electron carrier, chlorophyll electron transport system|negative regulation of polyferredoxin|down-regulation of polyferredoxin|inhibition of adrenodoxin-type ferredoxin|down regulation of electron donor activity|inhibition of iron-sulfur electron transfer carrier|down-regulation of monocluster bacterial-type ferredoxin|downregulation of rubredoxin|down regulation of chloroplast-type ferredoxin|negative regulation of monocluster bacterial-type ferredoxin|down regulation of amicyanin|inhibition of high-potential iron-sulfur carrier|negative regulation of dicluster bacterial-type ferredoxin|down-regulation of electron transporter activity|down-regulation of dicluster bacterial-type ferredoxin|negative regulation of electron transporter activity|downregulation of 2Fe-2S electron transfer carrier|downregulation of electron donor activity|inhibition of bacterial-type ferredoxin|downregulation of electron carrier, chlorophyll electron transport system|down-regulation of small blue copper electron carrier|negative regulation of small blue copper electron carrier|downregulation of chloroplast-type ferredoxin|down-regulation of electron carrier activity|negative regulation of 3Fe-4S/4Fe-4S electron transfer carrier|down regulation of rubredoxin|down-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|negative regulation of electron transfer flavoprotein, group I|inhibition of electron acceptor activity|down regulation of copper electron carrier|downregulation of azurin|downregulation of amicyanin|down-regulation of electron transfer flavoprotein, group I|inhibition of electron transfer flavoprotein|downregulation of electron transfer flavoprotein, group II|down regulation of adrenodoxin-type ferredoxin|down regulation of 2Fe-2S electron transfer carrier|down regulation of iron-sulfur electron transfer carrier|downregulation of redox-active disulfide bond electron carrier|downregulation of polyferredoxin|inhibition of electron transporter activity|down regulation of azurin|down regulation of electron transfer flavoprotein, group II|downregulation of copper electron carrier|negative regulation of thioredoxin-like 2Fe-2S ferredoxin|down-regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of bacterial-type ferredoxin|inhibition of electron carrier activity|downregulation of adrenodoxin-type ferredoxin|inhibition of mononuclear iron electron carrier|downregulation of iron-sulfur electron transfer carrier|inhibition of rubredoxin|down regulation of redox-active disulfide bond electron carrier|down-regulation of electron carrier, chlorophyll electron transport system|down regulation of polyferredoxin|negative regulation of electron carrier, chlorophyll electron transport system|negative regulation of electron donor activity|down-regulation of electron donor activity|downregulation of small blue copper electron carrier|inhibition of monocluster bacterial-type ferredoxin|negative regulation of chloroplast-type ferredoxin|down-regulation of chloroplast-type ferredoxin|inhibition of 2Fe-2S electron transfer carrier|inhibition of dicluster bacterial-type ferredoxin|down-regulation of amicyanin|downregulation of bacterial-type ferredoxin|negative regulation of amicyanin|negative regulation of high-potential iron-sulfur carrier|down-regulation of high-potential iron-sulfur carrier|down regulation of small blue copper electron carrier|inhibition of 3Fe-4S/4Fe-4S electron transfer carrier|inhibition of electron transfer flavoprotein, group II|inhibition of azurin|inhibition of electron transfer flavoprotein, group I|down-regulation of electron transfer flavoprotein|down-regulation of electron acceptor activity|negative regulation of electron acceptor activity|down regulation of mononuclear iron electron carrier|negative regulation of electron transfer flavoprotein|downregulation of thioredoxin-like 2Fe-2S ferredoxin|negative regulation of copper electron carrier|down-regulation of copper electron carrier|inhibition of redox-active disulfide bond electron carrier|down regulation of monocluster bacterial-type ferredoxin|inhibition of polyferredoxin|down-regulation of adrenodoxin-type ferredoxin|negative regulation of adrenodoxin-type ferredoxin|down-regulation of iron-sulfur electron transfer carrier|negative regulation of iron-sulfur electron transfer carrier|down regulation of electron transporter activity|down regulation of dicluster bacterial-type ferredoxin|downregulation of mononuclear iron electron carrier|down regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of 3Fe-4S/4Fe-4S electron transfer carrier|downregulation of monocluster bacterial-type ferredoxin|down-regulation of bacterial-type ferredoxin|downregulation of high-potential iron-sulfur carrier|down-regulation of rubredoxin|inhibition of small blue copper electron carrier|negative regulation of rubredoxin|negative regulation of bacterial-type ferredoxin|down regulation of electron carrier activity|inhibition of electron carrier, chlorophyll electron transport system|inhibition of electron donor activity|down regulation of electron transfer flavoprotein, group I|downregulation of dicluster bacterial-type ferredoxin|negative regulation of 2Fe-2S electron transfer carrier|down-regulation of 2Fe-2S electron transfer carrier|inhibition of chloroplast-type ferredoxin|downregulation of electron transporter activity|downregulation of electron acceptor activity|inhibition of amicyanin|downregulation of electron transfer flavoprotein|downregulation of 3Fe-4S/4Fe-4S electron transfer carrier|downregulation of electron carrier activity|down regulation of high-potential iron-sulfur carrier|down-regulation of electron transfer flavoprotein, group II|negative regulation of electron transfer flavoprotein, group II|downregulation of electron transfer flavoprotein, group I|down-regulation of azurin|negative regulation of azurin|inhibition of thioredoxin-like 2Fe-2S ferredoxin http://purl.obolibrary.org/obo/GO_1904733 GO:1904732 biolink:BiologicalProcess regulation of electron transfer activity Any process that modulates the frequency, rate or extent of electron transfer activity. go-plus.json regulation of electron carrier, chlorophyll electron transport system|regulation of electron donor activity|regulation of rubredoxin|regulation of chloroplast-type ferredoxin|regulation of amicyanin|regulation of 2Fe-2S electron transfer carrier|regulation of electron transfer flavoprotein, group II|regulation of azurin|regulation of copper electron carrier|regulation of adrenodoxin-type ferredoxin|regulation of redox-active disulfide bond electron carrier|regulation of iron-sulfur electron transfer carrier|regulation of polyferredoxin|regulation of bacterial-type ferredoxin|regulation of small blue copper electron carrier|regulation of mononuclear iron electron carrier|regulation of thioredoxin-like 2Fe-2S ferredoxin|regulation of monocluster bacterial-type ferredoxin|regulation of electron transporter activity|regulation of dicluster bacterial-type ferredoxin|regulation of high-potential iron-sulfur carrier|regulation of 3Fe-4S/4Fe-4S electron transfer carrier|regulation of electron transfer flavoprotein, group I|regulation of electron transfer flavoprotein|regulation of electron acceptor activity http://purl.obolibrary.org/obo/GO_1904732 GO:1904731 biolink:BiologicalProcess positive regulation of intestinal lipid absorption Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption. go-plus.json up-regulation of intestinal lipid absorption|upregulation of intestinal lipid absorption|up regulation of intestinal lipid absorption|activation of intestinal lipid absorption http://purl.obolibrary.org/obo/GO_1904731 GO:1904730 biolink:BiologicalProcess negative regulation of intestinal lipid absorption Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption. go-plus.json inhibition of intestinal lipid absorption|down regulation of intestinal lipid absorption|downregulation of intestinal lipid absorption|down-regulation of intestinal lipid absorption http://purl.obolibrary.org/obo/GO_1904730 CHEBI:132224 biolink:ChemicalSubstance 4-O-({poly[(2R)-1-glycerylphosphonato]}-[2R]-1-glycerylphosphonato)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_132224 chebi_ph7_3 GO:1904749 biolink:BiologicalProcess regulation of protein localization to nucleolus Any process that modulates the frequency, rate or extent of protein localization to nucleolus. go-plus.json regulation of protein localization in nucleolus|regulation of protein localisation in nucleolus|regulation of protein localisation to nucleolus http://purl.obolibrary.org/obo/GO_1904749 GO:1904748 biolink:BiologicalProcess regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in development. go-plus.json regulation of apoptotic cell death involved in anatomical structure development|regulation of apoptosis involved in development of an anatomical structure|regulation of activation of apoptosis involved in development of an anatomical structure|regulation of commitment to apoptosis involved in anatomical structure development|regulation of apoptotic programmed cell death involved in development of an anatomical structure|regulation of apoptotic process involved in development of an anatomical structure|regulation of type I programmed cell death involved in development of an anatomical structure|regulation of induction of apoptosis involved in development of an anatomical structure|regulation of apoptosis activator activity involved in development of an anatomical structure|regulation of programmed cell death by apoptosis involved in anatomical structure development|regulation of induction of apoptosis by p53 involved in anatomical structure development|regulation of apoptotic program involved in anatomical structure development|regulation of apoptotic cell death involved in development of an anatomical structure|regulation of signaling (initiator) caspase activity involved in anatomical structure development|regulation of apoptosis signaling involved in anatomical structure development|regulation of commitment to apoptosis involved in development of an anatomical structure|regulation of apoptosis involved in anatomical structure development|regulation of programmed cell death by apoptosis involved in development of an anatomical structure|regulation of activation of apoptosis involved in anatomical structure development|regulation of apoptotic program involved in development of an anatomical structure|regulation of induction of apoptosis by p53 involved in development of an anatomical structure|regulation of apoptotic programmed cell death involved in anatomical structure development|regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|regulation of apoptotic process involved in anatomical structure development|regulation of type I programmed cell death involved in anatomical structure development|regulation of apoptosis activator activity involved in anatomical structure development|regulation of induction of apoptosis involved in anatomical structure development|regulation of apoptosis signaling involved in development of an anatomical structure http://purl.obolibrary.org/obo/GO_1904748 GO:1904747 biolink:BiologicalProcess positive regulation of apoptotic process involved in development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. go-plus.json up regulation of apoptotic process involved in development of an anatomical structure|positive regulation of induction of apoptosis involved in anatomical structure development|upregulation of induction of apoptosis involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of apoptosis activator activity involved in anatomical structure development|activation of apoptosis signaling involved in anatomical structure development|positive regulation of apoptotic program involved in anatomical structure development|positive regulation of induction of apoptosis by p53 involved in anatomical structure development|up-regulation of apoptosis involved in anatomical structure development|up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|up-regulation of activation of apoptosis involved in anatomical structure development|up-regulation of apoptotic program involved in development of an anatomical structure|upregulation of programmed cell death by apoptosis involved in anatomical structure development|up regulation of apoptotic program involved in anatomical structure development|up regulation of induction of apoptosis by p53 involved in anatomical structure development|activation of commitment to apoptosis involved in development of an anatomical structure|activation of type I programmed cell death involved in anatomical structure development|activation of signaling (initiator) caspase activity involved in development of an anatomical structure|upregulation of apoptosis involved in development of an anatomical structure|upregulation of activation of apoptosis involved in development of an anatomical structure|activation of induction of apoptosis involved in anatomical structure development|up regulation of apoptotic cell death involved in anatomical structure development|activation of apoptosis activator activity involved in anatomical structure development|up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|activation of apoptotic cell death involved in anatomical structure development|up-regulation of apoptotic programmed cell death involved in anatomical structure development|activation of apoptotic programmed cell death involved in anatomical structure development|positive regulation of apoptosis signaling involved in anatomical structure development|activation of apoptotic process involved in anatomical structure development|up-regulation of apoptosis signaling involved in development of an anatomical structure|positive regulation of apoptotic cell death involved in anatomical structure development|up-regulation of apoptotic process involved in development|up-regulation of apoptotic process involved in anatomical structure development|upregulation of signaling (initiator) caspase activity involved in anatomical structure development|upregulation of apoptotic cell death involved in development of an anatomical structure|activation of apoptosis involved in anatomical structure development|positive regulation of commitment to apoptosis involved in development of an anatomical structure|activation of apoptotic program involved in development of an anatomical structure|upregulation of commitment to apoptosis involved in anatomical structure development|activation of induction of apoptosis by p53 involved in development of an anatomical structure|up regulation of apoptosis signaling involved in anatomical structure development|activation of activation of apoptosis involved in anatomical structure development|up regulation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptotic programmed cell death involved in development of an anatomical structure|up regulation of commitment to apoptosis involved in development of an anatomical structure|upregulation of apoptotic process involved in development of an anatomical structure|up-regulation of type I programmed cell death involved in anatomical structure development|up regulation of apoptosis activator activity involved in development of an anatomical structure|up regulation of induction of apoptosis involved in development of an anatomical structure|up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|positive regulation of type I programmed cell death involved in development of an anatomical structure|up-regulation of induction of apoptosis involved in anatomical structure development|up-regulation of apoptosis activator activity involved in anatomical structure development|positive regulation of apoptosis involved in anatomical structure development|positive regulation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of induction of apoptosis involved in development of an anatomical structure|up regulation of programmed cell death by apoptosis involved in anatomical structure development|upregulation of induction of apoptosis by p53 involved in anatomical structure development|positive regulation of apoptotic program involved in development of an anatomical structure|upregulation of apoptotic program involved in anatomical structure development|positive regulation of activation of apoptosis involved in anatomical structure development|activation of apoptosis signaling involved in development of an anatomical structure|positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure|up-regulation of apoptosis involved in development of an anatomical structure|up-regulation of activation of apoptosis involved in development of an anatomical structure|activation of programmed cell death by apoptosis involved in anatomical structure development|up regulation of apoptosis involved in anatomical structure development|up regulation of apoptotic program involved in development of an anatomical structure|up regulation of activation of apoptosis involved in anatomical structure development|up regulation of induction of apoptosis by p53 involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in anatomical structure development|upregulation of programmed cell death by apoptosis involved in development of an anatomical structure|activation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptotic process involved in development|up regulation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of apoptotic programmed cell death involved in anatomical structure development|activation of induction of apoptosis involved in development of an anatomical structure|up-regulation of commitment to apoptosis involved in anatomical structure development|activation of apoptosis activator activity involved in development of an anatomical structure|up regulation of apoptotic cell death involved in development of an anatomical structure|positive regulation of apoptotic process involved in anatomical structure development|positive regulation of apoptosis signaling involved in development of an anatomical structure|upregulation of apoptosis signaling involved in anatomical structure development|activation of apoptotic cell death involved in development of an anatomical structure|up-regulation of apoptotic programmed cell death involved in development of an anatomical structure|up-regulation of apoptotic cell death involved in anatomical structure development|activation of apoptotic programmed cell death involved in development of an anatomical structure|positive regulation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of apoptotic cell death involved in development of an anatomical structure|up regulation of apoptotic programmed cell death involved in anatomical structure development|activation of apoptosis involved in development of an anatomical structure|activation of apoptotic process involved in development of an anatomical structure|up-regulation of apoptotic process involved in development of an anatomical structure|upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|upregulation of type I programmed cell death involved in anatomical structure development|upregulation of commitment to apoptosis involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in anatomical structure development|up regulation of apoptotic process involved in anatomical structure development|activation of activation of apoptosis involved in development of an anatomical structure|upregulation of induction of apoptosis involved in anatomical structure development|up regulation of apoptosis signaling involved in development of an anatomical structure|up-regulation of apoptotic program involved in anatomical structure development|up-regulation of type I programmed cell death involved in development of an anatomical structure|up-regulation of induction of apoptosis by p53 involved in anatomical structure development|activation of commitment to apoptosis involved in anatomical structure development|up-regulation of apoptosis activator activity involved in development of an anatomical structure|up-regulation of induction of apoptosis involved in development of an anatomical structure|activation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of apoptosis involved in development of an anatomical structure|upregulation of apoptosis involved in anatomical structure development|up regulation of programmed cell death by apoptosis involved in development of an anatomical structure|upregulation of apoptotic program involved in development of an anatomical structure|positive regulation of activation of apoptosis involved in development of an anatomical structure|upregulation of induction of apoptosis by p53 involved in development of an anatomical structure|upregulation of activation of apoptosis involved in anatomical structure development|up regulation of apoptotic process involved in development|up-regulation of programmed cell death by apoptosis involved in anatomical structure development|activation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of apoptosis involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of activation of apoptosis involved in development of an anatomical structure|upregulation of apoptotic cell death involved in anatomical structure development|up-regulation of apoptosis signaling involved in anatomical structure development|activation of apoptotic process involved in development|positive regulation of commitment to apoptosis involved in anatomical structure development|activation of apoptotic program involved in anatomical structure development|activation of induction of apoptosis by p53 involved in anatomical structure development|up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|up regulation of type I programmed cell death involved in anatomical structure development|upregulation of apoptotic programmed cell death involved in anatomical structure development|up-regulation of commitment to apoptosis involved in development of an anatomical structure|positive regulation of apoptotic programmed cell death involved in development of an anatomical structure|upregulation of apoptotic process involved in anatomical structure development|upregulation of apoptosis signaling involved in development of an anatomical structure|positive regulation of apoptotic process involved in development of an anatomical structure|up regulation of commitment to apoptosis involved in anatomical structure development|up regulation of induction of apoptosis involved in anatomical structure development|up-regulation of signaling (initiator) caspase activity involved in anatomical structure development|up-regulation of apoptotic cell death involved in development of an anatomical structure|up regulation of apoptosis activator activity involved in anatomical structure development|upregulation of type I programmed cell death involved in development of an anatomical structure|positive regulation of type I programmed cell death involved in anatomical structure development|up regulation of apoptotic programmed cell death involved in development of an anatomical structure|positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure http://purl.obolibrary.org/obo/GO_1904747 GO:1904746 biolink:BiologicalProcess negative regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. go-plus.json down regulation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of commitment to apoptosis involved in anatomical structure development|downregulation of apoptotic cell death involved in anatomical structure development|down regulation of activation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic process involved in development of an anatomical structure|inhibition of apoptosis signaling involved in development of an anatomical structure|down regulation of type I programmed cell death involved in development of an anatomical structure|down-regulation of apoptosis signaling involved in anatomical structure development|negative regulation of apoptosis signaling involved in anatomical structure development|inhibition of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of type I programmed cell death involved in anatomical structure development|down regulation of induction of apoptosis involved in development of an anatomical structure|down regulation of apoptosis activator activity involved in development of an anatomical structure|down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in anatomical structure development|down-regulation of apoptosis activator activity involved in anatomical structure development|negative regulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of induction of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis involved in anatomical structure development|down-regulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of apoptosis activator activity involved in anatomical structure development|down regulation of commitment to apoptosis involved in anatomical structure development|down regulation of programmed cell death by apoptosis involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of apoptotic program involved in anatomical structure development|downregulation of type I programmed cell death involved in development of an anatomical structure|down regulation of apoptotic process involved in development of an anatomical structure|inhibition of apoptotic process involved in development|downregulation of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis activator activity involved in development of an anatomical structure|downregulation of induction of apoptosis involved in development of an anatomical structure|inhibition of apoptotic programmed cell death involved in development of an anatomical structure|inhibition of apoptosis involved in development of an anatomical structure|inhibition of apoptotic process involved in development of an anatomical structure|down-regulation of apoptosis involved in anatomical structure development|negative regulation of apoptosis involved in anatomical structure development|downregulation of programmed cell death by apoptosis involved in anatomical structure development|down regulation of apoptotic cell death involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure|down-regulation of apoptotic program involved in development of an anatomical structure|down-regulation of activation of apoptosis involved in anatomical structure development|inhibition of activation of apoptosis involved in development of an anatomical structure|down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|negative regulation of apoptotic program involved in development of an anatomical structure|negative regulation of activation of apoptosis involved in anatomical structure development|down regulation of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of apoptotic cell death involved in anatomical structure development|down regulation of apoptotic program involved in anatomical structure development|down-regulation of apoptotic cell death involved in anatomical structure development|down regulation of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis signaling involved in anatomical structure development|negative regulation of apoptotic programmed cell death involved in anatomical structure development|inhibition of commitment to apoptosis involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of apoptotic process involved in anatomical structure development|downregulation of apoptotic cell death involved in development of an anatomical structure|negative regulation of apoptotic process involved in anatomical structure development|downregulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of apoptosis signaling involved in development of an anatomical structure|downregulation of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of apoptosis signaling involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in development of an anatomical structure|inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of type I programmed cell death involved in development of an anatomical structure|inhibition of type I programmed cell death involved in anatomical structure development|down regulation of apoptosis signaling involved in anatomical structure development|negative regulation of induction of apoptosis involved in development of an anatomical structure|inhibition of induction of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis involved in development of an anatomical structure|negative regulation of apoptosis activator activity involved in development of an anatomical structure|inhibition of apoptosis activator activity involved in anatomical structure development|down-regulation of apoptosis activator activity involved in development of an anatomical structure|inhibition of apoptotic program involved in anatomical structure development|inhibition of apoptotic cell death involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis involved in anatomical structure development|down regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in anatomical structure development|down regulation of apoptotic process involved in development|downregulation of induction of apoptosis by p53 involved in development of an anatomical structure|down-regulation of programmed cell death by apoptosis involved in anatomical structure development|downregulation of activation of apoptosis involved in anatomical structure development|downregulation of apoptotic program involved in development of an anatomical structure|down-regulation of apoptosis involved in development of an anatomical structure|negative regulation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of activation of apoptosis involved in development of an anatomical structure|negative regulation of activation of apoptosis involved in development of an anatomical structure|down regulation of apoptosis involved in anatomical structure development|downregulation of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of activation of apoptosis involved in anatomical structure development|down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of apoptotic cell death involved in development of an anatomical structure|downregulation of apoptotic process involved in anatomical structure development|down regulation of induction of apoptosis by p53 involved in development of an anatomical structure|inhibition of apoptosis signaling involved in anatomical structure development|downregulation of apoptotic process involved in development|negative regulation of apoptotic cell death involved in development of an anatomical structure|down regulation of type I programmed cell death involved in anatomical structure development|down regulation of apoptotic program involved in development of an anatomical structure|down regulation of apoptosis activator activity involved in anatomical structure development|downregulation of apoptosis signaling involved in development of an anatomical structure|down-regulation of signaling (initiator) caspase activity involved in anatomical structure development|down regulation of induction of apoptosis involved in anatomical structure development|negative regulation of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in development of an anatomical structure|inhibition of commitment to apoptosis involved in development of an anatomical structure|negative regulation of commitment to apoptosis involved in anatomical structure development|negative regulation of apoptotic programmed cell death involved in development of an anatomical structure|down-regulation of commitment to apoptosis involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in anatomical structure development|down-regulation of apoptotic process involved in development of an anatomical structure|down regulation of apoptotic programmed cell death involved in anatomical structure development|negative regulation of apoptotic process involved in development of an anatomical structure|downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down regulation of apoptotic process involved in anatomical structure development|downregulation of type I programmed cell death involved in anatomical structure development|down regulation of apoptosis signaling involved in development of an anatomical structure|inhibition of type I programmed cell death involved in development of an anatomical structure|downregulation of induction of apoptosis involved in anatomical structure development|downregulation of apoptosis activator activity involved in anatomical structure development|inhibition of apoptotic programmed cell death involved in anatomical structure development|inhibition of apoptotic process involved in anatomical structure development|inhibition of apoptosis activator activity involved in development of an anatomical structure|inhibition of induction of apoptosis involved in development of an anatomical structure|inhibition of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis by p53 involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in development of an anatomical structure|inhibition of activation of apoptosis involved in anatomical structure development|down regulation of apoptotic cell death involved in anatomical structure development|negative regulation of apoptotic program involved in anatomical structure development|downregulation of apoptosis involved in development of an anatomical structure|down-regulation of apoptotic program involved in anatomical structure development|inhibition of apoptotic program involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in anatomical structure development|inhibition of apoptotic cell death involved in development of an anatomical structure|downregulation of activation of apoptosis involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down-regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_1904746 GO:1904745 biolink:BiologicalProcess Atg1/ULK1 kinase complex assembly The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex. go-plus.json Atg1p signalling complex formation|Atg1p signalling complex assembly|ULK1-ATG13-FIP200 complex assembly|ATG1/ULK1 signaling complex formation|ATG1-ATG13 complex formation|ATG1 kinase complex formation|ULK1 signaling complex assembly|ULK1-ATG13-RB1CC1 complex assembly|ULK1 signaling complex formation|ULK1-ATG13-RB1CC1 complex formation|ATG1/ULK1 kinase complex formation|ATG1-ATG13 complex assembly|ATG1 kinase complex assembly|ATG1/ULK1 signaling complex assembly|ULK1-ATG13-FIP200 complex formation http://purl.obolibrary.org/obo/GO_1904745 GO:1904744 biolink:BiologicalProcess positive regulation of telomeric DNA binding Any process that activates or increases the frequency, rate or extent of telomeric DNA binding. go-plus.json up-regulation of telomere binding|activation of telomere binding|up-regulation of telomeric repeat binding|up regulation of telomeric DNA binding|activation of telomeric repeat binding|activation of telomeric DNA binding|positive regulation of telomere binding|up regulation of telomere binding|positive regulation of telomeric repeat binding|up regulation of telomeric repeat binding|up-regulation of telomeric DNA binding|upregulation of telomere binding|upregulation of telomeric repeat binding|upregulation of telomeric DNA binding http://purl.obolibrary.org/obo/GO_1904744 GO:1904743 biolink:BiologicalProcess negative regulation of telomeric DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding. go-plus.json down regulation of telomeric DNA binding|downregulation of telomeric DNA binding|down-regulation of telomere binding|negative regulation of telomere binding|down-regulation of telomeric repeat binding|down-regulation of telomeric DNA binding|negative regulation of telomeric repeat binding|downregulation of telomere binding|inhibition of telomeric DNA binding|downregulation of telomeric repeat binding|down regulation of telomere binding|inhibition of telomere binding|down regulation of telomeric repeat binding|inhibition of telomeric repeat binding http://purl.obolibrary.org/obo/GO_1904743 GO:1904742 biolink:BiologicalProcess regulation of telomeric DNA binding Any process that modulates the frequency, rate or extent of telomeric DNA binding. go-plus.json regulation of telomere binding|regulation of telomeric repeat binding http://purl.obolibrary.org/obo/GO_1904742 GO:1904741 biolink:BiologicalProcess obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of global transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter, global|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904741 GO:1904740 biolink:BiologicalProcess obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter OBSOLETE. A transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by RNA polymerase II transcription factor activity|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by general transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904740 GO:1904750 biolink:BiologicalProcess negative regulation of protein localization to nucleolus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus. go-plus.json down-regulation of protein localization to nucleolus|inhibition of protein localisation in nucleolus|inhibition of protein localization to nucleolus|down-regulation of protein localisation to nucleolus|negative regulation of protein localisation to nucleolus|down regulation of protein localization in nucleolus|downregulation of protein localization in nucleolus|inhibition of protein localisation to nucleolus|down regulation of protein localisation in nucleolus|down regulation of protein localization to nucleolus|downregulation of protein localisation in nucleolus|down-regulation of protein localization in nucleolus|negative regulation of protein localization in nucleolus|downregulation of protein localization to nucleolus|down regulation of protein localisation to nucleolus|inhibition of protein localization in nucleolus|down-regulation of protein localisation in nucleolus|negative regulation of protein localisation in nucleolus|downregulation of protein localisation to nucleolus http://purl.obolibrary.org/obo/GO_1904750 CHEBI:132232 biolink:ChemicalSubstance ethylenediaminetriacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132232 CHEBI:132233 biolink:ChemicalSubstance 1-phenylpropan-2-amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132233 GO:1904759 biolink:BiologicalProcess protein localization to equatorial microtubule organizing center A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center. go-plus.json protein localization to eMTOC|protein localisation in equatorial microtubule organizing center|protein localization in equatorial microtubule organizing center|protein localisation to equatorial microtubule organizing center http://purl.obolibrary.org/obo/GO_1904759 GO:1904758 biolink:BiologicalProcess protein localization to new growing cell tip A process in which a protein is transported to, or maintained in, a location within a new growing cell tip. go-plus.json protein localization to new growing cell end|protein localisation to new growing cell tip|protein localization to post-new end take-off new cell tip|protein localization to post-NETO new cell tip|protein localization to post-NETO new cell end|protein localisation in new growing cell tip|protein localization to new cell tip after activation of bipolar cell growth|protein localization in new growing cell tip http://purl.obolibrary.org/obo/GO_1904758 GO:1904757 biolink:BiologicalProcess positive regulation of gut granule assembly Any process that activates or increases the frequency, rate or extent of gut granule assembly. go-plus.json upregulation of gut granule assembly|up regulation of gut granule formation|activation of gut granule formation|positive regulation of gut granule formation|upregulation of gut granule biogenesis|up-regulation of gut granule assembly|activation of gut granule assembly|activation of gut granule biogenesis|up-regulation of gut granule biogenesis|up-regulation of gut granule formation|up regulation of gut granule assembly|upregulation of gut granule formation|positive regulation of gut granule biogenesis|up regulation of gut granule biogenesis http://purl.obolibrary.org/obo/GO_1904757 GO:1904756 biolink:BiologicalProcess negative regulation of gut granule assembly Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly. go-plus.json downregulation of gut granule biogenesis|inhibition of gut granule assembly|downregulation of gut granule formation|down regulation of gut granule biogenesis|inhibition of gut granule biogenesis|negative regulation of gut granule formation|down-regulation of gut granule formation|down-regulation of gut granule assembly|inhibition of gut granule formation|negative regulation of gut granule biogenesis|down-regulation of gut granule biogenesis|downregulation of gut granule assembly|down regulation of gut granule formation|down regulation of gut granule assembly http://purl.obolibrary.org/obo/GO_1904756 GO:1904755 biolink:BiologicalProcess regulation of gut granule assembly Any process that modulates the frequency, rate or extent of gut granule assembly. go-plus.json regulation of gut granule formation|regulation of gut granule biogenesis http://purl.obolibrary.org/obo/GO_1904755 GO:1904754 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell migration Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration. go-plus.json upregulation of vascular associated smooth muscle cell migration|up regulation of vascular smooth muscle cell migration|activation of vascular smooth muscle cell migration|positive regulation of vascular smooth muscle cell migration|up-regulation of vascular associated smooth muscle cell migration|activation of vascular associated smooth muscle cell migration|up-regulation of vascular smooth muscle cell migration|up regulation of vascular associated smooth muscle cell migration|upregulation of vascular smooth muscle cell migration http://purl.obolibrary.org/obo/GO_1904754 GO:1904753 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell migration Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration. go-plus.json inhibition of vascular associated smooth muscle cell migration|down regulation of vascular smooth muscle cell migration|downregulation of vascular smooth muscle cell migration|negative regulation of vascular smooth muscle cell migration|down-regulation of vascular smooth muscle cell migration|down-regulation of vascular associated smooth muscle cell migration|inhibition of vascular smooth muscle cell migration|downregulation of vascular associated smooth muscle cell migration|down regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_1904753 GO:1904752 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell migration Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration. go-plus.json regulation of vascular smooth muscle cell migration http://purl.obolibrary.org/obo/GO_1904752 GO:1904751 biolink:BiologicalProcess positive regulation of protein localization to nucleolus Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus. go-plus.json up regulation of protein localisation to nucleolus|positive regulation of protein localisation to nucleolus|activation of protein localisation to nucleolus|up-regulation of protein localisation in nucleolus|upregulation of protein localization in nucleolus|up-regulation of protein localization to nucleolus|upregulation of protein localisation in nucleolus|up-regulation of protein localisation to nucleolus|up regulation of protein localization in nucleolus|upregulation of protein localization to nucleolus|positive regulation of protein localization in nucleolus|activation of protein localization in nucleolus|up regulation of protein localisation in nucleolus|upregulation of protein localisation to nucleolus|activation of protein localisation in nucleolus|positive regulation of protein localisation in nucleolus|up regulation of protein localization to nucleolus|activation of protein localization to nucleolus|up-regulation of protein localization in nucleolus http://purl.obolibrary.org/obo/GO_1904751 GO:1904761 biolink:BiologicalProcess negative regulation of myofibroblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation. go-plus.json down-regulation of myofibroblast differentiation|negative regulation of myofibroblast cell differentiation|down-regulation of myofibroblast cell differentiation|inhibition of myofibroblast differentiation|downregulation of myofibroblast cell differentiation|down regulation of myofibroblast cell differentiation|inhibition of myofibroblast cell differentiation|down regulation of myofibroblast differentiation|downregulation of myofibroblast differentiation http://purl.obolibrary.org/obo/GO_1904761 GO:1904760 biolink:BiologicalProcess regulation of myofibroblast differentiation Any process that modulates the frequency, rate or extent of myofibroblast differentiation. go-plus.json regulation of myofibroblast cell differentiation http://purl.obolibrary.org/obo/GO_1904760 CHEBI:132201 biolink:ChemicalSubstance 11(S)-hydroxy-14(S),15(S)-hepoxilin A3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132201 chebi_ph7_3 CHEBI:132200 biolink:ChemicalSubstance 11(S),15(S)-dihydroxy-14(R)-(S-glutathionyl)-5(Z),8(Z),12(E)-icosatrienoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132200 chebi_ph7_3 CHEBI:132202 biolink:ChemicalSubstance (2R)-CDP-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132202 NCBITaxon:13615 biolink:OrganismalEntity Monodelphis go-plus.json short-tailed opossums http://purl.obolibrary.org/obo/NCBITaxon_13615 GO:1904769 biolink:MolecularActivity isopentadecanoic acid binding Binding to isopentadecanoic acid. go-plus.json 13-methylmyristic acid binding http://purl.obolibrary.org/obo/GO_1904769 CHEBI:132218 biolink:ChemicalSubstance 5(S)-hydroperoxy-18(R)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132218 chebi_ph7_3 GO:1904768 biolink:MolecularActivity all-trans-retinol binding Binding to all-trans-retinol. go-plus.json http://purl.obolibrary.org/obo/GO_1904768 NCBITaxon:13616 biolink:OrganismalEntity Monodelphis domestica go-plus.json gray short-tailed opossum http://purl.obolibrary.org/obo/NCBITaxon_13616 GO:1904767 biolink:MolecularActivity octanoic acid binding Binding to octanoic acid. go-plus.json caprylic acid binding http://purl.obolibrary.org/obo/GO_1904767 GO:1904766 biolink:BiologicalProcess negative regulation of macroautophagy by TORC1 signaling A TORC1 signaling that results in negative regulation of macroautophagy. go-plus.json negative regulation of autophagy in response to cellular starvation by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signaling|negative regulation of autophagy in response to cellular starvation by TORC1 signal transduction|negative regulation of non-specific autophagy by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signal transduction|negative regulation of non-specific autophagy by TORC1 signal transduction|negative regulation of macroautophagy by TORC1 signal transduction http://purl.obolibrary.org/obo/GO_1904766 CHEBI:132219 biolink:ChemicalSubstance 5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132219 chebi_ph7_3 GO:1904765 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter in response to maltose Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a maltose stimulus. go-plus.json stimulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of global transcription from Pol II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter, global involved in cellular response to maltose stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to maltose stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus http://purl.obolibrary.org/obo/GO_1904765 GO:1904764 biolink:BiologicalProcess chaperone-mediated autophagy translocation complex disassembly The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components. go-plus.json CMA receptor complex disassembly|chaperone-mediated autophagy receptor complex disassembly|CMA translocation complex disassembly http://purl.obolibrary.org/obo/GO_1904764 GO:1904763 biolink:BiologicalProcess chaperone-mediated autophagy translocation complex assembly The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex. go-plus.json CMA translocation complex assembly|chaperone-mediated autophagy translocation complex formation|CMA receptor complex formation|chaperone-mediated autophagy receptor complex assembly|chaperone-mediated autophagy receptor complex formation|CMA translocation complex formation|CMA receptor complex assembly http://purl.obolibrary.org/obo/GO_1904763 GO:1904762 biolink:BiologicalProcess positive regulation of myofibroblast differentiation Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation. go-plus.json positive regulation of myofibroblast cell differentiation|up regulation of myofibroblast cell differentiation|up-regulation of myofibroblast differentiation|upregulation of myofibroblast cell differentiation|upregulation of myofibroblast differentiation|up-regulation of myofibroblast cell differentiation|activation of myofibroblast cell differentiation|up regulation of myofibroblast differentiation|activation of myofibroblast differentiation http://purl.obolibrary.org/obo/GO_1904762 GO:1904772 biolink:BiologicalProcess response to tetrachloromethane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus. go-plus.json response to carbon tetrachloride|response to CCL4 http://purl.obolibrary.org/obo/GO_1904772 CHEBI:132210 biolink:ChemicalSubstance N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132210 chebi_ph7_3 GO:1904771 biolink:BiologicalProcess obsolete cellular response to doxorubicin OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904771 GO:1904770 biolink:BiologicalProcess intramembranous bone morphogenesis The developmental process by which an intramembranous bone is generated and organized. go-plus.json membrane bone morphogenesis|intramembranous bones morphogenesis http://purl.obolibrary.org/obo/GO_1904770 CHEBI:132211 biolink:ChemicalSubstance 4-O-[(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132211 chebi_ph7_3 GO:1904779 biolink:BiologicalProcess regulation of protein localization to centrosome Any process that modulates the frequency, rate or extent of protein localization to centrosome. go-plus.json regulation of protein localisation to centrosome http://purl.obolibrary.org/obo/GO_1904779 GO:1904778 biolink:BiologicalProcess positive regulation of protein localization to cell cortex Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. go-plus.json upregulation of protein localization to cell cortex|upregulation of protein localisation to cell cortex|up regulation of protein localization to cell cortex|activation of protein localization to cell cortex|up regulation of protein localisation to cell cortex|activation of protein localisation to cell cortex|positive regulation of protein localisation to cell cortex|up-regulation of protein localization to cell cortex|up-regulation of protein localisation to cell cortex http://purl.obolibrary.org/obo/GO_1904778 GO:1904777 biolink:BiologicalProcess negative regulation of protein localization to cell cortex Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. go-plus.json down regulation of protein localization to cell cortex|downregulation of protein localization to cell cortex|down regulation of protein localisation to cell cortex|downregulation of protein localisation to cell cortex|down-regulation of protein localization to cell cortex|inhibition of protein localization to cell cortex|down-regulation of protein localisation to cell cortex|negative regulation of protein localisation to cell cortex|inhibition of protein localisation to cell cortex http://purl.obolibrary.org/obo/GO_1904777 GO:1904776 biolink:BiologicalProcess regulation of protein localization to cell cortex Any process that modulates the frequency, rate or extent of protein localization to cell cortex. go-plus.json regulation of protein localisation to cell cortex http://purl.obolibrary.org/obo/GO_1904776 GO:1904775 biolink:BiologicalProcess positive regulation of ubiquinone biosynthetic process Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process. go-plus.json activation of ubiquinone formation|activation of coenzyme Q10 biosynthetic process|activation of coenzyme Q10 biosynthesis|activation of coenzyme Q8 biosynthetic process|activation of coenzyme Q8 biosynthesis|positive regulation of coenzyme Q biosynthetic process|positive regulation of coenzyme Q biosynthesis|activation of coenzyme Q biosynthetic process|activation of coenzyme Q biosynthesis|activation of coenzyme Q9 biosynthetic process|activation of coenzyme Q9 biosynthesis|up regulation of ubiquinone biosynthesis|positive regulation of ubiquinone anabolism|up regulation of ubiquinone biosynthetic process|positive regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q6 biosynthetic process|activation of ubiquinone biosynthesis|activation of ubiquinone biosynthetic process|positive regulation of ubiquinone biosynthesis|up regulation of ubiquinone anabolism|positive regulation of coenzyme Q8 biosynthetic process|up regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q8 biosynthesis|up regulation of coenzyme Q6 biosynthetic process|up-regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q10 biosynthesis|positive regulation of ubiquinone synthesis|positive regulation of coenzyme Q9 biosynthesis|positive regulation of coenzyme Q9 biosynthetic process|up regulation of coenzyme Q8 biosynthesis|up regulation of coenzyme Q8 biosynthetic process|up regulation of coenzyme Q9 biosynthetic process|up regulation of ubiquinone synthesis|up regulation of coenzyme Q9 biosynthesis|positive regulation of ubiquinone formation|up-regulation of coenzyme Q biosynthetic process|up-regulation of coenzyme Q biosynthesis|up regulation of ubiquinone formation|upregulation of coenzyme Q10 biosynthesis|upregulation of coenzyme Q10 biosynthetic process|upregulation of ubiquinone anabolism|upregulation of coenzyme Q6 biosynthetic process|up-regulation of ubiquinone biosynthesis|upregulation of coenzyme Q6 biosynthesis|up-regulation of ubiquinone biosynthetic process|upregulation of coenzyme Q8 biosynthesis|upregulation of coenzyme Q8 biosynthetic process|upregulation of coenzyme Q9 biosynthetic process|upregulation of ubiquinone synthesis|upregulation of coenzyme Q9 biosynthesis|upregulation of coenzyme Q biosynthetic process|upregulation of coenzyme Q biosynthesis|upregulation of ubiquinone formation|up-regulation of ubiquinone anabolism|up-regulation of coenzyme Q6 biosynthetic process|activation of ubiquinone anabolism|up regulation of coenzyme Q10 biosynthesis|upregulation of ubiquinone biosynthesis|upregulation of ubiquinone biosynthetic process|up regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q10 biosynthesis|up-regulation of coenzyme Q8 biosynthetic process|up-regulation of coenzyme Q8 biosynthesis|positive regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q9 biosynthesis|up-regulation of coenzyme Q9 biosynthetic process|up-regulation of ubiquinone synthesis|activation of ubiquinone synthesis|up regulation of coenzyme Q biosynthesis|activation of coenzyme Q6 biosynthesis|activation of coenzyme Q6 biosynthetic process|up regulation of coenzyme Q biosynthetic process|up-regulation of ubiquinone formation http://purl.obolibrary.org/obo/GO_1904775 GO:1904774 biolink:BiologicalProcess negative regulation of ubiquinone biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process. go-plus.json downregulation of ubiquinone biosynthesis|downregulation of ubiquinone biosynthetic process|down-regulation of coenzyme Q8 biosynthetic process|negative regulation of coenzyme Q8 biosynthetic process|down-regulation of coenzyme Q8 biosynthesis|negative regulation of coenzyme Q8 biosynthesis|negative regulation of coenzyme Q9 biosynthesis|negative regulation of coenzyme Q9 biosynthetic process|down-regulation of coenzyme Q9 biosynthetic process|down-regulation of coenzyme Q9 biosynthesis|down-regulation of ubiquinone synthesis|negative regulation of ubiquinone synthesis|down-regulation of coenzyme Q biosynthetic process|negative regulation of coenzyme Q biosynthetic process|negative regulation of coenzyme Q biosynthesis|down-regulation of coenzyme Q biosynthesis|down-regulation of ubiquinone formation|negative regulation of ubiquinone formation|downregulation of ubiquinone anabolism|downregulation of coenzyme Q6 biosynthetic process|downregulation of coenzyme Q6 biosynthesis|down-regulation of ubiquinone biosynthetic process|down-regulation of ubiquinone biosynthesis|negative regulation of ubiquinone biosynthesis|inhibition of coenzyme Q10 biosynthetic process|inhibition of coenzyme Q10 biosynthesis|downregulation of coenzyme Q8 biosynthetic process|downregulation of coenzyme Q8 biosynthesis|inhibition of coenzyme Q biosynthesis|downregulation of coenzyme Q9 biosynthesis|inhibition of coenzyme Q biosynthetic process|downregulation of coenzyme Q9 biosynthetic process|down regulation of coenzyme Q6 biosynthesis|down regulation of ubiquinone anabolism|downregulation of ubiquinone synthesis|down regulation of coenzyme Q6 biosynthetic process|inhibition of ubiquinone anabolism|down regulation of coenzyme Q8 biosynthesis|down regulation of coenzyme Q8 biosynthetic process|down regulation of coenzyme Q9 biosynthetic process|inhibition of ubiquinone biosynthesis|downregulation of ubiquinone formation|down regulation of coenzyme Q9 biosynthesis|inhibition of ubiquinone biosynthetic process|down regulation of ubiquinone synthesis|inhibition of ubiquinone synthesis|down regulation of coenzyme Q10 biosynthesis|down regulation of coenzyme Q10 biosynthetic process|down regulation of ubiquinone formation|inhibition of coenzyme Q6 biosynthetic process|inhibition of coenzyme Q6 biosynthesis|inhibition of ubiquinone formation|inhibition of coenzyme Q8 biosynthesis|downregulation of coenzyme Q10 biosynthesis|inhibition of coenzyme Q8 biosynthetic process|downregulation of coenzyme Q10 biosynthetic process|inhibition of coenzyme Q9 biosynthetic process|inhibition of coenzyme Q9 biosynthesis|down regulation of coenzyme Q biosynthesis|down regulation of coenzyme Q biosynthetic process|down regulation of ubiquinone biosynthesis|down regulation of ubiquinone biosynthetic process|downregulation of coenzyme Q biosynthetic process|downregulation of coenzyme Q biosynthesis|negative regulation of coenzyme Q10 biosynthetic process|down-regulation of coenzyme Q10 biosynthetic process|down-regulation of coenzyme Q10 biosynthesis|negative regulation of coenzyme Q10 biosynthesis|negative regulation of coenzyme Q6 biosynthesis|down-regulation of ubiquinone anabolism|negative regulation of ubiquinone anabolism|down-regulation of coenzyme Q6 biosynthesis|negative regulation of coenzyme Q6 biosynthetic process|down-regulation of coenzyme Q6 biosynthetic process http://purl.obolibrary.org/obo/GO_1904774 GO:1904773 biolink:BiologicalProcess obsolete cellular response to tetrachloromethane OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus. go-plus.json cellular response to CCL4|cellular response to carbon tetrachloride http://purl.obolibrary.org/obo/GO_1904773 GO:1904783 biolink:BiologicalProcess positive regulation of NMDA glutamate receptor activity Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity. go-plus.json positive regulation of N-methyl-D-aspartate selective glutamate receptor activity|upregulation of NMDA glutamate receptor activity|up regulation of N-methyl-D-aspartate selective glutamate receptor activity|up-regulation of NMDA receptor|up-regulation of NMDA glutamate receptor activity|activation of NMDA glutamate receptor activity|upregulation of N-methyl-D-aspartate selective glutamate receptor activity|upregulation of NMDA receptor|up-regulation of N-methyl-D-aspartate selective glutamate receptor activity|activation of N-methyl-D-aspartate selective glutamate receptor activity|up regulation of NMDA glutamate receptor activity|up regulation of NMDA receptor|activation of NMDA receptor|positive regulation of NMDA receptor http://purl.obolibrary.org/obo/GO_1904783 GO:1904782 biolink:BiologicalProcess negative regulation of NMDA glutamate receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity. go-plus.json negative regulation of NMDA receptor|down-regulation of NMDA receptor|down regulation of NMDA glutamate receptor activity|inhibition of NMDA glutamate receptor activity|inhibition of NMDA receptor|downregulation of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of N-methyl-D-aspartate selective glutamate receptor activity|inhibition of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of NMDA receptor|down-regulation of NMDA glutamate receptor activity|downregulation of NMDA receptor|downregulation of NMDA glutamate receptor activity|negative regulation of N-methyl-D-aspartate selective glutamate receptor activity|down-regulation of N-methyl-D-aspartate selective glutamate receptor activity http://purl.obolibrary.org/obo/GO_1904782 GO:1904781 biolink:BiologicalProcess positive regulation of protein localization to centrosome Any process that activates or increases the frequency, rate or extent of protein localization to centrosome. go-plus.json upregulation of protein localization to centrosome|up-regulation of protein localisation to centrosome|activation of protein localisation to centrosome|up-regulation of protein localization to centrosome|activation of protein localization to centrosome|positive regulation of protein localisation to centrosome|up regulation of protein localisation to centrosome|up regulation of protein localization to centrosome|upregulation of protein localisation to centrosome http://purl.obolibrary.org/obo/GO_1904781 GO:1904780 biolink:BiologicalProcess negative regulation of protein localization to centrosome Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome. go-plus.json negative regulation of protein localisation to centrosome|down-regulation of protein localisation to centrosome|down-regulation of protein localization to centrosome|downregulation of protein localisation to centrosome|down regulation of protein localisation to centrosome|inhibition of protein localisation to centrosome|downregulation of protein localization to centrosome|down regulation of protein localization to centrosome|inhibition of protein localization to centrosome http://purl.obolibrary.org/obo/GO_1904780 CHEBI:39474 biolink:ChemicalSubstance polyazaalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39474 CHEBI:8191 biolink:ChemicalSubstance all-trans-phytoene go-plus.json http://purl.obolibrary.org/obo/CHEBI_8191 chebi_ph7_3 GO:1904789 biolink:BiologicalProcess regulation of mitotic actomyosin contractile ring maintenance Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance. go-plus.json regulation of contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_1904789 GO:1904788 biolink:BiologicalProcess obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion. go-plus.json positive regulation of induction of conjugation with cellular fusion by regulation of global transcription from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter, global|positive regulation of induction of conjugation with cellular fusion by regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of induction of conjugation with cellular fusion by global transcription regulation from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_1904788 GO:1904787 biolink:BiologicalProcess positive regulation of asymmetric protein localization involved in cell fate determination Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination. go-plus.json up regulation of asymmetric protein localization involved in cell fate commitment|upregulation of asymmetric protein localisation involved in cell fate determination|upregulation of asymmetric protein localization resulting in cell fate commitment|upregulation of asymmetric protein localization involved in cell fate determination|up-regulation of cell fate commitment, asymmetric protein localization|upregulation of asymmetric protein localization involved in cell fate commitment|up regulation of asymmetric protein localisation involved in cell fate determination|positive regulation of asymmetric protein localisation involved in cell fate determination|activation of asymmetric protein localisation involved in cell fate determination|upregulation of cell fate commitment, asymmetric protein localization|up regulation of asymmetric protein localization involved in cell fate determination|up regulation of asymmetric protein localization resulting in cell fate commitment|up-regulation of asymmetric protein localization involved in cell fate commitment|positive regulation of asymmetric protein localization resulting in cell fate commitment|activation of asymmetric protein localization involved in cell fate commitment|activation of asymmetric protein localization resulting in cell fate commitment|activation of asymmetric protein localization involved in cell fate determination|up-regulation of asymmetric protein localisation involved in cell fate determination|up regulation of cell fate commitment, asymmetric protein localization|positive regulation of cell fate commitment, asymmetric protein localization|positive regulation of asymmetric protein localization involved in cell fate commitment|activation of cell fate commitment, asymmetric protein localization|up-regulation of asymmetric protein localization involved in cell fate determination|up-regulation of asymmetric protein localization resulting in cell fate commitment http://purl.obolibrary.org/obo/GO_1904787 GO:1904786 biolink:BiologicalProcess negative regulation of asymmetric protein localization involved in cell fate determination Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination. go-plus.json negative regulation of cell fate commitment, asymmetric protein localization|down-regulation of cell fate commitment, asymmetric protein localization|downregulation of asymmetric protein localization involved in cell fate commitment|down regulation of asymmetric protein localisation involved in cell fate determination|down regulation of asymmetric protein localization involved in cell fate commitment|inhibition of cell fate commitment, asymmetric protein localization|downregulation of asymmetric protein localisation involved in cell fate determination|inhibition of asymmetric protein localization involved in cell fate commitment|down regulation of asymmetric protein localization resulting in cell fate commitment|down regulation of asymmetric protein localization involved in cell fate determination|downregulation of asymmetric protein localization resulting in cell fate commitment|downregulation of asymmetric protein localization involved in cell fate determination|negative regulation of asymmetric protein localisation involved in cell fate determination|down-regulation of asymmetric protein localisation involved in cell fate determination|down regulation of cell fate commitment, asymmetric protein localization|inhibition of asymmetric protein localisation involved in cell fate determination|negative regulation of asymmetric protein localization resulting in cell fate commitment|down-regulation of asymmetric protein localization resulting in cell fate commitment|down-regulation of asymmetric protein localization involved in cell fate determination|downregulation of cell fate commitment, asymmetric protein localization|down-regulation of asymmetric protein localization involved in cell fate commitment|negative regulation of asymmetric protein localization involved in cell fate commitment|inhibition of asymmetric protein localization resulting in cell fate commitment|inhibition of asymmetric protein localization involved in cell fate determination http://purl.obolibrary.org/obo/GO_1904786 GO:1904785 biolink:BiologicalProcess regulation of asymmetric protein localization involved in cell fate determination Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination. go-plus.json regulation of asymmetric protein localization involved in cell fate commitment|regulation of asymmetric protein localisation involved in cell fate determination|regulation of asymmetric protein localization resulting in cell fate commitment|regulation of cell fate commitment, asymmetric protein localization http://purl.obolibrary.org/obo/GO_1904785 CHEBI:40460 biolink:ChemicalSubstance 2'-O-methyladenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_40460 GO:1904784 biolink:BiologicalProcess NLRP1 inflammasome complex assembly The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex. go-plus.json NALP1 inflammasome complex assembly|NLRP1 inflammasome complex formation|NALP1 inflammasome complex formation http://purl.obolibrary.org/obo/GO_1904784 GO:1904794 biolink:BiologicalProcess negative regulation of euchromatin binding Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding. go-plus.json down regulation of euchromatin binding|downregulation of euchromatin binding|down-regulation of euchromatin binding|inhibition of euchromatin binding http://purl.obolibrary.org/obo/GO_1904794 GO:1904793 biolink:BiologicalProcess regulation of euchromatin binding Any process that modulates the frequency, rate or extent of euchromatin binding. go-plus.json http://purl.obolibrary.org/obo/GO_1904793 GO:1904792 biolink:BiologicalProcess positive regulation of shelterin complex assembly Any process that activates or increases the frequency, rate or extent of shelterin complex assembly. go-plus.json positive regulation of shelterin complex formation|upregulation of telosome assembly|upregulation of Pot1 complex assembly|positive regulation of Pot1-Tpz1 complex assembly|up regulation of Pot1-Tpz1 complex assembly|up-regulation of shelterin complex formation|up regulation of telosome assembly|activation of telosome assembly|up regulation of Pot1 complex assembly|activation of Pot1 complex assembly|positive regulation of Pot1 complex assembly|upregulation of Pot1-Tpz1 complex assembly|upregulation of shelterin complex formation|up-regulation of telosome assembly|activation of Pot1-Tpz1 complex assembly|up-regulation of Pot1-Tpz1 complex assembly|up-regulation of Pot1 complex assembly|positive regulation of telosome assembly|up regulation of shelterin complex formation|activation of shelterin complex formation http://purl.obolibrary.org/obo/GO_1904792 GO:1904791 biolink:BiologicalProcess negative regulation of shelterin complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly. go-plus.json negative regulation of Pot1-Tpz1 complex assembly|down-regulation of Pot1-Tpz1 complex assembly|negative regulation of telosome assembly|down regulation of telosome assembly|down-regulation of shelterin complex formation|negative regulation of shelterin complex formation|downregulation of telosome assembly|down regulation of Pot1 complex assembly|downregulation of Pot1-Tpz1 complex assembly|inhibition of shelterin complex formation|downregulation of Pot1 complex assembly|down regulation of Pot1-Tpz1 complex assembly|inhibition of Pot1-Tpz1 complex assembly|down-regulation of telosome assembly|down-regulation of Pot1 complex assembly|negative regulation of Pot1 complex assembly|down regulation of shelterin complex formation|inhibition of telosome assembly|downregulation of shelterin complex formation|inhibition of Pot1 complex assembly http://purl.obolibrary.org/obo/GO_1904791 GO:1904790 biolink:BiologicalProcess regulation of shelterin complex assembly Any process that modulates the frequency, rate or extent of shelterin complex assembly. go-plus.json regulation of Pot1 complex assembly|regulation of Pot1-Tpz1 complex assembly|regulation of telosome assembly|regulation of shelterin complex formation http://purl.obolibrary.org/obo/GO_1904790 CHEBI:39482 biolink:ChemicalSubstance chloroolefin go-plus.json http://purl.obolibrary.org/obo/CHEBI_39482 CHEBI:64423 biolink:ChemicalSubstance phosphatidylcholine 34:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64423 chebi_ph7_3 CHEBI:64421 biolink:ChemicalSubstance dehydroaustinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64421 chebi_ph7_3 CHEBI:64427 biolink:ChemicalSubstance phosphatidyl-N,N-dimethylethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64427 chebi_ph7_3 CHEBI:64426 biolink:ChemicalSubstance cyclitol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_64426 CHEBI:64424 biolink:ChemicalSubstance phosphatidylcholine 34:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64424 chebi_ph7_3 CHEBI:64429 biolink:ChemicalSubstance chanoclavine-I aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_64429 CHEBI:64428 biolink:ChemicalSubstance H group go-plus.json http://purl.obolibrary.org/obo/CHEBI_64428 chebi_ph7_3 CHEBI:64433 biolink:ChemicalSubstance phosphatidylcholine 36:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64433 chebi_ph7_3 CHEBI:64436 biolink:ChemicalSubstance arugosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64436 CHEBI:88414 biolink:ChemicalSubstance (S)-2-methylbutanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_88414 chebi_ph7_3 CHEBI:64448 biolink:ChemicalSubstance arsonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64448 chebi_ph7_3 CHEBI:64450 biolink:ChemicalSubstance endocrocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64450 CHEBI:64454 biolink:ChemicalSubstance (+)-kotanin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64454 chebi_ph7_3 CHEBI:64459 biolink:ChemicalSubstance biaryl go-plus.json http://purl.obolibrary.org/obo/CHEBI_64459 CHEBI:156263 biolink:ChemicalSubstance O-(S-decanoylpantetheine-4-phosphoryl)serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_156263 CHEBI:156262 biolink:ChemicalSubstance O-(S-octanoylpantetheine-4-phosphoryl)serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_156262 chebi_ph7_3 CHEBI:64462 biolink:ChemicalSubstance 8,8'-bicoumarins go-plus.json http://purl.obolibrary.org/obo/CHEBI_64462 CHEBI:64461 biolink:ChemicalSubstance bicoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64461 CHEBI:64465 biolink:ChemicalSubstance demethylkotanin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64465 CHEBI:132286 biolink:ChemicalSubstance 1-O-(11-hydroxyoleoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132286 chebi_ph7_3 CHEBI:132280 biolink:ChemicalSubstance 1-O-[(9R,10S)-epoxystearoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132280 chebi_ph7_3 NCBITaxon:13684 biolink:OrganismalEntity Parastagonospora nodorum go-plus.json Septoria nodorum|Phaeosphaeria nodorum|Leptosphaeria nodorum|Stagonospora nodorum http://purl.obolibrary.org/obo/NCBITaxon_13684 CHEBI:132285 biolink:ChemicalSubstance 1-O-(8-hydroxyoleoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132285 chebi_ph7_3 CHEBI:156255 biolink:ChemicalSubstance S-adenosyl-D-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_156255 CHEBI:64474 biolink:ChemicalSubstance p-hydroxyphenyl lignin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64474 CHEBI:64473 biolink:ChemicalSubstance orlandin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64473 CHEBI:64477 biolink:ChemicalSubstance monolignol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64477 CHEBI:64476 biolink:ChemicalSubstance syringal lignin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64476 CHEBI:64475 biolink:ChemicalSubstance guaiacyl lignin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64475 CHEBI:132297 biolink:ChemicalSubstance methamphetamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132297 chebi_ph7_3 CHEBI:64479 biolink:ChemicalSubstance O-(pantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64479 chebi_ph7_3 CHEBI:64480 biolink:ChemicalSubstance phosphatidylcholine O-38:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64480 chebi_ph7_3 CHEBI:64483 biolink:ChemicalSubstance lysophosphatidylcholine 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64483 chebi_ph7_3 CHEBI:64482 biolink:ChemicalSubstance phosphatidylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64482 chebi_ph7_3 CHEBI:64489 biolink:ChemicalSubstance 1-myristoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64489 chebi_ph7_3 CHEBI:88456 biolink:ChemicalSubstance 8,15-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_88456 DDANAT:0000098 biolink:OntologyClass inner basal disc Central portion of the basal disc. Composed of stalk cells. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000098 CHEBI:88457 biolink:ChemicalSubstance 14,15-EpETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_88457 CHEBI:132265 biolink:ChemicalSubstance (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132265 CHEBI:132264 biolink:ChemicalSubstance 5,10-dihydrophenazine-1,6-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132264 CHEBI:132266 biolink:ChemicalSubstance (10aS)-10,10a-dihydrophenazine-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132266 CHEBI:132269 biolink:ChemicalSubstance (3E)-octenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_132269 CHEBI:132261 biolink:ChemicalSubstance (1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132261 CHEBI:132263 biolink:ChemicalSubstance (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132263 CHEBI:132262 biolink:ChemicalSubstance (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132262 GO:1904709 biolink:BiologicalProcess negative regulation of granulosa cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process. go-plus.json inhibition of granulosa cell apoptosis|inhibition of granulosa cell apoptotic process|inhibition of granulosa cell of ovary apoptotic process|inhibition of granulosa cell of ovary apoptosis|down regulation of granulosa cell of ovary apoptosis|negative regulation of granulosa cell apoptosis|down-regulation of granulosa cell apoptosis|downregulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell of ovary apoptotic process|down-regulation of granulosa cell apoptotic process|downregulation of granulosa cell of ovary apoptotic process|downregulation of granulosa cell apoptosis|down-regulation of granulosa cell of ovary apoptosis|negative regulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell apoptosis|downregulation of granulosa cell apoptotic process|negative regulation of granulosa cell of ovary apoptotic process|down-regulation of granulosa cell of ovary apoptotic process|down regulation of granulosa cell apoptotic process http://purl.obolibrary.org/obo/GO_1904709 GO:1904708 biolink:BiologicalProcess regulation of granulosa cell apoptotic process Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process. go-plus.json regulation of granulosa cell of ovary apoptosis|regulation of granulosa cell of ovary apoptotic process|regulation of granulosa cell apoptosis http://purl.obolibrary.org/obo/GO_1904708 GO:1904707 biolink:BiologicalProcess positive regulation of vascular associated smooth muscle cell proliferation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. go-plus.json up regulation of vascular smooth muscle cell proliferation|activation of vascular smooth muscle cell proliferation|upregulation of VSMC proliferation|up-regulation of VSMC proliferation|up-regulation of vascular smooth muscle cell proliferation|activation of VSMC proliferation|positive regulation of vascular smooth muscle cell proliferation|upregulation of vascular smooth muscle cell proliferation|positive regulation of VSMC proliferation|up regulation of VSMC proliferation http://purl.obolibrary.org/obo/GO_1904707 CHEBI:64492 biolink:ChemicalSubstance ferricrocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64492 GO:1904706 biolink:BiologicalProcess negative regulation of vascular associated smooth muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. go-plus.json downregulation of VSMC proliferation|downregulation of vascular smooth muscle cell proliferation|down regulation of VSMC proliferation|inhibition of VSMC proliferation|down-regulation of vascular smooth muscle cell proliferation|inhibition of vascular smooth muscle cell proliferation|negative regulation of VSMC proliferation|down-regulation of VSMC proliferation|negative regulation of vascular smooth muscle cell proliferation|down regulation of vascular smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904706 GO:1904705 biolink:BiologicalProcess regulation of vascular associated smooth muscle cell proliferation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation. go-plus.json regulation of VSMC proliferation|regulation of vascular smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 GO:1904704 biolink:BiologicalProcess positive regulation of protein localization to adherens junction Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json up-regulation of protein localization in cell-cell adherens junction|up regulation of protein localisation to cell-cell adherens junction|positive regulation of protein localisation to cell-cell adherens junction|activation of protein localisation to cell-cell adherens junction|up-regulation of protein localisation in cell-cell adherens junction|upregulation of protein localization in cell-cell adherens junction|up-regulation of protein localization to cell-cell adherens junction|upregulation of protein localisation in cell-cell adherens junction|up-regulation of protein localisation to cell-cell adherens junction|upregulation of protein localization to cell-cell adherens junction|up regulation of protein localization in cell-cell adherens junction|positive regulation of protein localization in cell-cell adherens junction|activation of protein localization in cell-cell adherens junction|up regulation of protein localisation in cell-cell adherens junction|upregulation of protein localisation to cell-cell adherens junction|activation of protein localisation in cell-cell adherens junction|positive regulation of protein localisation in cell-cell adherens junction|up regulation of protein localization to cell-cell adherens junction|activation of protein localization to cell-cell adherens junction http://purl.obolibrary.org/obo/GO_1904704 GO:1904703 biolink:BiologicalProcess negative regulation of protein localization to adherens junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json downregulation of protein localisation to cell-cell adherens junction|down-regulation of protein localization to cell-cell adherens junction|inhibition of protein localisation in cell-cell adherens junction|negative regulation of protein localisation to cell-cell adherens junction|down-regulation of protein localisation to cell-cell adherens junction|inhibition of protein localization to cell-cell adherens junction|down regulation of protein localization in cell-cell adherens junction|downregulation of protein localization in cell-cell adherens junction|inhibition of protein localisation to cell-cell adherens junction|down regulation of protein localisation in cell-cell adherens junction|down regulation of protein localization to cell-cell adherens junction|downregulation of protein localisation in cell-cell adherens junction|negative regulation of protein localization in cell-cell adherens junction|down-regulation of protein localization in cell-cell adherens junction|downregulation of protein localization to cell-cell adherens junction|down regulation of protein localisation to cell-cell adherens junction|down-regulation of protein localisation in cell-cell adherens junction|inhibition of protein localization in cell-cell adherens junction|negative regulation of protein localisation in cell-cell adherens junction http://purl.obolibrary.org/obo/GO_1904703 CHEBI:64496 biolink:ChemicalSubstance lysophosphatidylcholine O-16:0/0:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64496 chebi_ph7_3 GO:1904702 biolink:BiologicalProcess regulation of protein localization to adherens junction Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. go-plus.json regulation of protein localization in cell-cell adherens junction|regulation of protein localisation in cell-cell adherens junction|regulation of protein localisation to cell-cell adherens junction http://purl.obolibrary.org/obo/GO_1904702 GO:1904701 biolink:BiologicalProcess Wnt-Frizzled-LRP5/6 complex assembly The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex. go-plus.json Frizzled-LRP5/6 complex formation|Wnt-FZD-LRP5/6 trimeric complex assembly|Wnt-FZD-LRP5/6 trimeric complex formation|Wnt-induced Frizzled-LRP5/6 complex formation|Wnt receptor complex assembly|Wnt-induced Frizzled-LRP5/6 complex assembly|WNT-FZD-LRP5 complex assembly|WNT-FZD-LRP6 complex assembly|WNT-FZD-LRP6 complex formation|WNT-FZD-LRP5 complex formation|Frizzled-LRP5/6 complex assembly http://purl.obolibrary.org/obo/GO_1904701 CHEBI:64494 biolink:ChemicalSubstance tatiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64494 GO:1904700 biolink:BiologicalProcess granulosa cell apoptotic process Any apoptotic process in a granulosa cell. go-plus.json granulosa cell apoptosis|granulosa cell of ovary apoptosis|granulosa cell of ovary apoptotic process http://purl.obolibrary.org/obo/GO_1904700 CHEBI:64493 biolink:ChemicalSubstance sarcinapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64493 DDANAT:0000088 biolink:OntologyClass prestalk A region Anterior-most region of the prestalk zone characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). go-plus.json pstA region http://purl.obolibrary.org/obo/DDANAT_0000088 DDANAT:0000087 biolink:OntologyClass prestalk region The prestalk region is located at the most apical part of the organism. It consists of about one quarter of the cells. go-plus.json pst region http://purl.obolibrary.org/obo/DDANAT_0000087 CHEBI:64499 biolink:ChemicalSubstance shamixanthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64499 chebi_ph7_3 CHEBI:64497 biolink:ChemicalSubstance cspyrone B1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64497 DDANAT:0000089 biolink:OntologyClass basal disc Conical-shaped structure that anchors the stalk to the substratum. Composed of anterior-like cells. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000089 CHEBI:132276 biolink:ChemicalSubstance (11S,12R)-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_132276 DDANAT:0000094 biolink:OntologyClass sorus Ovoid structure supported by the stalk and that contains the spores. go-plus.json spore head http://purl.obolibrary.org/obo/DDANAT_0000094 CHEBI:132275 biolink:ChemicalSubstance (14R,15S)-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_132275 CHEBI:132278 biolink:ChemicalSubstance 1-O-[(9S,10R)-epoxystearoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132278 chebi_ph7_3 CHEBI:132277 biolink:ChemicalSubstance (11R,12S)-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_132277 DDANAT:0000091 biolink:OntologyClass prestalk AB core region Cone-shaped area of the prestalk zone that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. go-plus.json prestalk AB region|pstAB region http://purl.obolibrary.org/obo/DDANAT_0000091 DDANAT:0000093 biolink:OntologyClass stalk Tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. go-plus.json sorophore http://purl.obolibrary.org/obo/DDANAT_0000093 CHEBI:132271 biolink:ChemicalSubstance (2E,5Z)-octadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_132271 CHEBI:132274 biolink:ChemicalSubstance (14S,15R)-EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_132274 CHEBI:74622 biolink:ChemicalSubstance 15-oxo-beta-bilirubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_74622 CHEBI:25699 biolink:ChemicalSubstance organic ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_25699 CHEBI:25698 biolink:ChemicalSubstance ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_25698 chebi_ph7_3 CHEBI:74621 biolink:ChemicalSubstance 5-oxo-delta-bilirubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_74621 CHEBI:25697 biolink:ChemicalSubstance organic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25697 CHEBI:25696 biolink:ChemicalSubstance organic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_25696 CHEBI:74628 biolink:ChemicalSubstance 3-vinylbacteriochlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_74628 CHEBI:25690 biolink:ChemicalSubstance ommatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25690 CHEBI:25693 biolink:ChemicalSubstance organic heteromonocyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25693 CHEBI:25692 biolink:ChemicalSubstance ommochrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_25692 CHEBI:11047 biolink:ChemicalSubstance (S)-3-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11047 chebi_ph7_3 CL:1000334 biolink:Cell enterocyte of epithelium of small intestine An enterocyte that is part of the epithelium of small intestine. go-plus.json http://purl.obolibrary.org/obo/CL_1000334 UBERON:0012437 biolink:AnatomicalEntity epithelial-mesenchymal boundary A anatomical line that adjacent_to a epithelium and adjacent_to a mesenchyme. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012437 CHEBI:74620 biolink:ChemicalSubstance 15-demethylaclacinomycin T go-plus.json http://purl.obolibrary.org/obo/CHEBI_74620 CHEBI:11041 biolink:ChemicalSubstance (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_11041 NCBITaxon:3977 biolink:OrganismalEntity Euphorbiaceae go-plus.json spurge family http://purl.obolibrary.org/obo/NCBITaxon_3977 CHEBI:74637 biolink:ChemicalSubstance N(6)-L-threonylcarbamoyladenine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74637 CHEBI:50648 biolink:ChemicalSubstance 9-cis-retinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50648 CHEBI:74636 biolink:ChemicalSubstance N(6)-L-threonylcarbamoyladenine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74636 CHEBI:50646 biolink:ChemicalSubstance bone density conservation agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50646 CHEBI:74638 biolink:ChemicalSubstance N(6)-dimethylallyladenine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74638 UBERON:0012430 biolink:AnatomicalEntity tunica fibrosa of eyeball The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. go-plus.json corneosclera|fibrous tunic|fibrous layer of eyeball|tunica fibrosa http://purl.obolibrary.org/obo/UBERON_0012430 UBERON:0036422 biolink:AnatomicalEntity wall of pulmonary artery go-plus.json pulmonary arterial wall http://purl.obolibrary.org/obo/UBERON_0036422 CL:1000322 biolink:Cell pancreatic goblet cell A goblet cell that is part of the epithelium of pancreatic duct. go-plus.json goblet cell of epithelium of pancreatic duct http://purl.obolibrary.org/obo/CL_1000322 CL:1000320 biolink:Cell large intestine goblet cell A goblet cell that is part of the epithelium of large intestine. go-plus.json goblet cell of epithelium of large intestine http://purl.obolibrary.org/obo/CL_1000320 CHEBI:35026 biolink:ChemicalSubstance triethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35026 UBERON:0012425 biolink:AnatomicalEntity striated border microvillus layer A microvillus layer that is striated and found in the intestine. go-plus.json striated border http://purl.obolibrary.org/obo/UBERON_0012425 UBERON:0012429 biolink:AnatomicalEntity hematopoietic tissue Blood-forming tissue, consisting of reticular fibers and cells. go-plus.json hematopoietic tissue|textus haemopoieticus|bone marrow tissue|hemopoietic tissue|haemopoietic tissue http://purl.obolibrary.org/obo/UBERON_0012429 CHEBI:35020 biolink:ChemicalSubstance tributyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35020 chebi_ph7_3 CHEBI:74631 biolink:ChemicalSubstance cysteamine S-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74631 chebi_ph7_3 CHEBI:74630 biolink:ChemicalSubstance glycosyloxyisoflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_74630 CHEBI:25676 biolink:ChemicalSubstance oligopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25676 CHEBI:49643 biolink:ChemicalSubstance (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID go-plus.json http://purl.obolibrary.org/obo/CHEBI_49643 CHEBI:74643 biolink:ChemicalSubstance 2-thio-N(6)-dimethylallyladenine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74643 CHEBI:74646 biolink:ChemicalSubstance 2-methylthio-N(6)-dimethylallyladenine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74646 CHEBI:50630 biolink:ChemicalSubstance cyclooxygenase 1 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50630 CHEBI:74645 biolink:ChemicalSubstance 2-methylthio-N(6)-dimethylallyladenine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74645 CHEBI:74648 biolink:ChemicalSubstance 2-thio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74648 CHEBI:74649 biolink:ChemicalSubstance 2-thio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74649 UBERON:0012423 biolink:AnatomicalEntity layer of microvilli A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified] go-plus.json microvillus|microvilli http://purl.obolibrary.org/obo/UBERON_0012423 CHEBI:60001 biolink:ChemicalSubstance pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60001 chebi_ph7_3 CHEBI:60000 biolink:ChemicalSubstance 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60000 chebi_ph7_3 CHEBI:60002 biolink:ChemicalSubstance D-glycero-D-manno-heptose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60002 chebi_ph7_3 UBERON:0012416 biolink:AnatomicalEntity respiratory system arterial smooth muscle go-plus.json http://purl.obolibrary.org/obo/UBERON_0012416 CHEBI:60005 biolink:ChemicalSubstance 3-amino-4-hydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60005 chebi_ph7_3 CHEBI:60004 biolink:ChemicalSubstance mixture go-plus.json http://purl.obolibrary.org/obo/CHEBI_60004 CHEBI:60007 biolink:ChemicalSubstance sulfoglycolithocholate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60007 chebi_ph7_3 CHEBI:60006 biolink:ChemicalSubstance laricitrin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60006 chebi_ph7_3 CHEBI:60009 biolink:ChemicalSubstance UDP-6-sulfoquinovose(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60009 chebi_ph7_3 UBERON:0012418 biolink:AnatomicalEntity respiratory system venous smooth muscle A smooth muscle tissue that is part of a respiratory system venous blood vessel. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012418 CHEBI:60008 biolink:ChemicalSubstance glycolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60008 chebi_ph7_3 CHEBI:11060 biolink:ChemicalSubstance (S)-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_11060 chebi_ph7_3 CHEBI:74640 biolink:ChemicalSubstance N-acetyl-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_74640 CHEBI:74642 biolink:ChemicalSubstance 2-thio-N(6)-dimethylallyladenine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74642 CHEBI:74655 biolink:ChemicalSubstance 7-methylguanosine 5'-triphosphate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_74655 CHEBI:50621 biolink:ChemicalSubstance gamma-glutamylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50621 CHEBI:74656 biolink:ChemicalSubstance O(4)-phosphonato-D-tyrosine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74656 chebi_ph7_3 CHEBI:50626 biolink:ChemicalSubstance 2-hydroxyhexadecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_50626 chebi_ph7_3 CHEBI:49637 biolink:ChemicalSubstance hydrogen atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_49637 CHEBI:74659 biolink:ChemicalSubstance N(2),N(2),N(7)-trimethylguanosine 5'-triphosphate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74659 CHEBI:74658 biolink:ChemicalSubstance N(2),N(2),N(7)-trimethylguanosine 5'-triphosphate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_74658 UBERON:0036441 biolink:AnatomicalEntity wall of uterine tube go-plus.json wall of oviduct|wall of fallopian tube|uterine tube wall http://purl.obolibrary.org/obo/UBERON_0036441 CHEBI:50629 biolink:ChemicalSubstance cyclooxygenase 2 inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50629 CHEBI:50627 biolink:ChemicalSubstance EC 3.2.1.1 (alpha-amylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50627 CL:1000349 biolink:Cell basal cell of epithelium of bronchus A basal cell found in the bronchus epithelium. go-plus.json basal cell of bronchus http://purl.obolibrary.org/obo/CL_1000349 CL:1000347 biolink:Cell vacuolar absorptive cell of epithelium of colon A columnar cell of the colon that is part of the colonic epithelium. go-plus.json http://purl.obolibrary.org/obo/CL_1000347 CHEBI:25681 biolink:ChemicalSubstance omega-3 fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25681 CHEBI:60014 biolink:ChemicalSubstance 3'-O-methyltricetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60014 chebi_ph7_3 CHEBI:60016 biolink:ChemicalSubstance 3',5'-di-O-methyltricetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60016 chebi_ph7_3 CHEBI:60015 biolink:ChemicalSubstance 2,3-dehydroacyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60015 chebi_ph7_3 CHEBI:35008 biolink:ChemicalSubstance tetralin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35008 chebi_ph7_3 CHEBI:74650 biolink:ChemicalSubstance 2-methylthio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74650 CHEBI:74653 biolink:ChemicalSubstance 3-thio-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_74653 CHEBI:74666 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z)-3-oxotetracosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74666 CHEBI:74665 biolink:ChemicalSubstance (10Z,13Z,16Z)-3-oxodocosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74665 CHEBI:74668 biolink:ChemicalSubstance N(2),N(2),N(7)-trimethylguanosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74668 CHEBI:74667 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74667 chebi_ph7_3 UBERON:0012482 biolink:AnatomicalEntity submucosa of cloaca A submucosa that is part of a cloaca [Automatically generated definition]. go-plus.json cloaca submucosa|cloacal submucosa http://purl.obolibrary.org/obo/UBERON_0012482 CHEBI:74669 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74669 chebi_ph7_3 UBERON:0012481 biolink:AnatomicalEntity cloacal epithelium An epithelium that is part of a cloaca. go-plus.json cloacal endoderm http://purl.obolibrary.org/obo/UBERON_0012481 UBERON:0012480 biolink:AnatomicalEntity cloacal mucosa A mucosa that is part of a cloaca [Automatically generated definition]. go-plus.json cloaca mucosa|mucosa of organ of cloaca|mucosa of cloaca|mucous membrane of cloaca|cloaca mucosa of organ|cloaca mucous membrane|cloaca organ mucosa|cloacal mucous membrane|organ mucosa of cloaca http://purl.obolibrary.org/obo/UBERON_0012480 CHEBI:50613 biolink:ChemicalSubstance (S)-2-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50613 CHEBI:25656 biolink:ChemicalSubstance octose go-plus.json http://purl.obolibrary.org/obo/CHEBI_25656 CHEBI:50612 biolink:ChemicalSubstance (R)-2-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50612 UBERON:0012486 biolink:AnatomicalEntity muscle layer of cloaca A muscular coat that is part of a cloaca. go-plus.json muscularis externa of cloaca|smooth muscle of cloaca http://purl.obolibrary.org/obo/UBERON_0012486 UBERON:0012485 biolink:AnatomicalEntity cloacal villus go-plus.json cloacal villi http://purl.obolibrary.org/obo/UBERON_0012485 CHEBI:11009 biolink:ChemicalSubstance (R)-3-phenyllactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11009 chebi_ph7_3 UBERON:0012483 biolink:AnatomicalEntity serosa of cloaca A serous membrane that is part of a cloaca [Automatically generated definition]. go-plus.json cloacal serosa|serous membrane of cloaca|cloaca serosa|cloaca serous membrane|visceral peritoneum of cloaca http://purl.obolibrary.org/obo/UBERON_0012483 CHEBI:50616 biolink:ChemicalSubstance iminoaspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50616 UBERON:0012489 biolink:AnatomicalEntity muscle layer of colon A muscular coat that is part of a colon. go-plus.json muscularis externa of colon|colon muscularis|muscular layer of colon|tunica muscularis coli|colonic muscularis propria|muscular coat of colon http://purl.obolibrary.org/obo/UBERON_0012489 CHEBI:60020 biolink:ChemicalSubstance 3',4',5'-O-trimethyltricetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60020 chebi_ph7_3 CHEBI:60023 biolink:ChemicalSubstance CoA-glutathione(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60023 chebi_ph7_3 UBERON:0012488 biolink:AnatomicalEntity muscle layer of duodenum A muscular coat that is part of a duodenum. go-plus.json smooth muscle of duodenum|muscularis propria of duodenum|muscularis externa of duodenum|duodenal muscularis propria http://purl.obolibrary.org/obo/UBERON_0012488 UBERON:0012487 biolink:AnatomicalEntity vaginal sphincter A sphincter muscle that is part of a vagina. go-plus.json sphincter of vagina http://purl.obolibrary.org/obo/UBERON_0012487 CHEBI:60025 biolink:ChemicalSubstance (5Z,7E,9E,14Z,17Z)-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60025 chebi_ph7_3 CHEBI:60027 biolink:ChemicalSubstance polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_60027 CHEBI:60029 biolink:ChemicalSubstance homopolymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_60029 CHEBI:74662 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74662 CHEBI:74663 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z,23Z)-3-oxohexacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74663 chebi_ph7_3 CHEBI:74677 biolink:ChemicalSubstance 5-aminomethyl-2-thiouridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74677 CHEBI:74676 biolink:ChemicalSubstance N(6)-methyladenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74676 CHEBI:74679 biolink:ChemicalSubstance 5-methylaminomethyl-2-thiouridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74679 CHEBI:74678 biolink:ChemicalSubstance 5-aminomethyl-2-thiouridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74678 CHEBI:50604 biolink:ChemicalSubstance 5-(methylsulfanyl)-2,3-dioxopentyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50604 CHEBI:50602 biolink:ChemicalSubstance precorrin-2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_50602 CHEBI:50601 biolink:ChemicalSubstance N(alpha)-methyl-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50601 UBERON:0012475 biolink:AnatomicalEntity skeleton of pectoral complex The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle. go-plus.json upper limb skeleton|set of bones of upper limb|skeleton of anterior limb/fin and girdle|pectoral complex skeleton|ossa membri superioris|bones of upper limb http://purl.obolibrary.org/obo/UBERON_0012475 CHEBI:50608 biolink:ChemicalSubstance (2S)-2-hydroxy-3-oxobutyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50608 CHEBI:50606 biolink:ChemicalSubstance 2-hydroxy-3-oxobutyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50606 CHEBI:50605 biolink:ChemicalSubstance 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50605 CHEBI:60032 biolink:ChemicalSubstance undecaprenyldiphosphonato-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysyl-D-alanyl-D-alanine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60032 chebi_ph7_3 UBERON:0012478 biolink:AnatomicalEntity cloacal gland A gland that is part of a cloaca. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012478 CHEBI:25661 biolink:ChemicalSubstance oleandomycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_25661 UBERON:0012477 biolink:AnatomicalEntity dorsal part of neck The posterior region of the neck, including the suboccipital region. go-plus.json nuchal region|nape|posterior part of neck|regio cervicalis posterior|nucha|posterior neck region|hindneck|nape of neck|back of neck|neck back|posterior cervical region http://purl.obolibrary.org/obo/UBERON_0012477 UBERON:0012476 biolink:AnatomicalEntity skeleton of pelvic complex The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle. go-plus.json pelvic complex skeleton|set of bones of lower limb|lower limb skeleton|ossa membri inferioris|skeleton of posterior limb/fin and girdle|bones of lower limb http://purl.obolibrary.org/obo/UBERON_0012476 CHEBI:60033 biolink:ChemicalSubstance lipid II(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60033 chebi_ph7_3 CHEBI:60038 biolink:ChemicalSubstance flavonoid oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60038 UBERON:0012469 biolink:AnatomicalEntity external anal region go-plus.json http://purl.obolibrary.org/obo/UBERON_0012469 CHEBI:60039 biolink:ChemicalSubstance L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60039 chebi_ph7_3 CHEBI:74671 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74671 chebi_ph7_3 CHEBI:74670 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74670 chebi_ph7_3 CHEBI:74673 biolink:ChemicalSubstance 5,6-dihydrouridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74673 CHEBI:74672 biolink:ChemicalSubstance 5,6-dihydrouridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74672 CHEBI:74675 biolink:ChemicalSubstance 5-methyluridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74675 CHEBI:74674 biolink:ChemicalSubstance 2'-O-methylguanosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74674 CHEBI:25633 biolink:ChemicalSubstance octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25633 NCBITaxon:3988 biolink:OrganismalEntity Ricinus communis go-plus.json Ricinus sanguineus|castor bean http://purl.obolibrary.org/obo/NCBITaxon_3988 CHEBI:49601 biolink:ChemicalSubstance Fe2S2 iron-sulfur cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_49601 chebi_ph7_3 NCBITaxon:3987 biolink:OrganismalEntity Ricinus go-plus.json Ricinus http://purl.obolibrary.org/obo/NCBITaxon_3987 NCBITaxon:3982 biolink:OrganismalEntity Manihot go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3982 CHEBI:25637 biolink:ChemicalSubstance octadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25637 CHEBI:49603 biolink:ChemicalSubstance lapatinib go-plus.json http://purl.obolibrary.org/obo/CHEBI_49603 CHEBI:25636 biolink:ChemicalSubstance octadienediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25636 CHEBI:25635 biolink:ChemicalSubstance octadecenynoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25635 NCBITaxon:3983 biolink:OrganismalEntity Manihot esculenta go-plus.json yuca|Manihot utilissima|cassava|tapioca|manioc http://purl.obolibrary.org/obo/NCBITaxon_3983 CHEBI:25634 biolink:ChemicalSubstance octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25634 UBERON:0012464 biolink:AnatomicalEntity cloacal vent The opening of the cloacal chamber to the outside of the organism. Birds maintain a single cloacal opening throughout their lives. go-plus.json vent|cloacal opening|cloacal orifice http://purl.obolibrary.org/obo/UBERON_0012464 UBERON:0012463 biolink:AnatomicalEntity cloacal lumen A anatomical space that is enclosed by a cloaca. go-plus.json cloacal chamber|cloaca lumen http://purl.obolibrary.org/obo/UBERON_0012463 CHEBI:60041 biolink:ChemicalSubstance cis-3-hydroxy-L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60041 chebi_ph7_3 CHEBI:60040 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60040 chebi_ph7_3 CHEBI:60043 biolink:ChemicalSubstance 5'-acylphosphoadenosine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60043 chebi_ph7_3 UBERON:0012468 biolink:AnatomicalEntity anal tooth Triangular calcified papillae (often five) placed radially around the anus of some Holothuriidae go-plus.json calcified anal papilla|perianal tooth|anal teeth|cloacal tooth http://purl.obolibrary.org/obo/UBERON_0012468 UBERON:0012467 biolink:AnatomicalEntity enclosed anatomical space An anatomical space with no opening to another space or to the exterior. go-plus.json closed anatomical space http://purl.obolibrary.org/obo/UBERON_0012467 CHEBI:60045 biolink:ChemicalSubstance tricetin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60045 chebi_ph7_3 UBERON:0012466 biolink:AnatomicalEntity extraembryonic cavity go-plus.json extraembryonic cavities http://purl.obolibrary.org/obo/UBERON_0012466 CL:1000313 biolink:Cell gastric goblet cell A goblet cell that is part of the epithelium of stomach. go-plus.json goblet cell of epithelium of stomach http://purl.obolibrary.org/obo/CL_1000313 UBERON:0012465 biolink:AnatomicalEntity lumen of terminal part of digestive tract A anatomical space that is enclosed by a terminal part of digestive tract. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012465 CHEBI:60047 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60047 chebi_ph7_3 CL:1000312 biolink:Cell bronchial goblet cell A goblet cell that is part of the epithelium of bronchus. go-plus.json goblet cell of epithelium of bronchus http://purl.obolibrary.org/obo/CL_1000312 CHEBI:60049 biolink:ChemicalSubstance cobalt-sirohydrochlorin(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60049 chebi_ph7_3 CHEBI:60048 biolink:ChemicalSubstance pelargonidin 3-O-rutinoside betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60048 chebi_ph7_3 CHEBI:11022 biolink:ChemicalSubstance (S)-4-amino-5-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11022 CHEBI:74680 biolink:ChemicalSubstance 5-methylaminomethyl-2-thiouridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74680 CHEBI:25639 biolink:ChemicalSubstance octadienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25639 CHEBI:74681 biolink:ChemicalSubstance 2'-O-methyladenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74681 CHEBI:74685 biolink:ChemicalSubstance 2'-O-methyluridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74685 CHEBI:25646 biolink:ChemicalSubstance octanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25646 chebi_ph7_3 UBERON:0012453 biolink:AnatomicalEntity nerve ending Specialized terminations of peripheral neurons. Nerve endings include NEUROEFFECTOR JUNCTION(s) by which neurons activate target organs and sensory receptors (see RECEPTORS, SENSORY) which transduce information from the various sensory modalities and send it centrally in the nervous system. Presynaptic nerve endings are PRESYNAPTIC TERMINALS. go-plus.json nerve ending http://purl.obolibrary.org/obo/UBERON_0012453 CHEBI:60050 biolink:ChemicalSubstance estrone 3-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60050 chebi_ph7_3 UBERON:0012451 biolink:AnatomicalEntity sensory receptor A sensory nerve ending that responds to a stimulus in the internal or external environment of an organism. In response to stimuli the sensory receptor initiates sensory transduction by creating graded potentials or action potentials in the same cell or in an adjacent one. go-plus.json sensory nerve ending|peripheral ending of sensory neuron http://purl.obolibrary.org/obo/UBERON_0012451 CHEBI:60052 biolink:ChemicalSubstance siroheme(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60052 chebi_ph7_3 CHEBI:60051 biolink:ChemicalSubstance N-formyl-D-kynurenine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60051 chebi_ph7_3 CHEBI:25640 biolink:ChemicalSubstance octamethylcyclotetrasiloxane go-plus.json http://purl.obolibrary.org/obo/CHEBI_25640 chebi_ph7_3 CHEBI:60053 biolink:ChemicalSubstance cobalt-precorrin-2(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60053 chebi_ph7_3 CHEBI:60056 biolink:ChemicalSubstance cocaine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60056 chebi_ph7_3 CHEBI:60055 biolink:ChemicalSubstance dermatan 6'-sulfate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60055 chebi_ph7_3 CHEBI:60058 biolink:ChemicalSubstance S-acylglutathionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60058 chebi_ph7_3 CHEBI:60057 biolink:ChemicalSubstance N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60057 chebi_ph7_3 UBERON:0012449 biolink:AnatomicalEntity mechanoreceptor A sensory receptor that responds to mechanical pressure or distortion. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012449 CHEBI:60059 biolink:ChemicalSubstance dermatan anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60059 chebi_ph7_3 CHEBI:74691 biolink:ChemicalSubstance trans-2-icosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74691 chebi_ph7_3 CHEBI:74693 biolink:ChemicalSubstance trans-2-tetracosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74693 chebi_ph7_3 CHEBI:74692 biolink:ChemicalSubstance trans-2-docosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74692 chebi_ph7_3 CHEBI:11010 biolink:ChemicalSubstance (R)-phenyllactoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_11010 CL:0002293 biolink:Cell epithelial cell of thymus An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. go-plus.json epithelial reticular cell of thymus|thymic epithelial cell|epithelial cell of thymus gland|epithelial reticular cell http://purl.obolibrary.org/obo/CL_0002293 CHEBI:74694 biolink:ChemicalSubstance 1-palmitoleoyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74694 chebi_ph7_3 CHEBI:74697 biolink:ChemicalSubstance 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74697 chebi_ph7_3 GO:0072056 biolink:BiologicalProcess pyramid development The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. go-plus.json kidney pyramid development|pyramids development|renal medulla development|renal pyramid development http://purl.obolibrary.org/obo/GO_0072056 GO:0047099 biolink:MolecularActivity CDP-4-dehydro-6-deoxyglucose reductase activity Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose. MetaCyc:1.17.1.1-RXN|EC:1.17.1.1 go-plus.json cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity|NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity|CDP-4-keto-deoxy-glucose reductase activity|CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity|CDP-4-keto-6-deoxyglucose reductase activity|CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity|cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047099 GO:0072055 biolink:BiologicalProcess renal cortex development The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072055 GO:0072054 biolink:BiologicalProcess renal outer medulla development The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla. go-plus.json outer renal medulla development http://purl.obolibrary.org/obo/GO_0072054 GO:0047098 biolink:MolecularActivity Latia-luciferin monooxygenase (demethylating) activity Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin. RHEA:12677|MetaCyc:1.14.99.21-RXN|EC:1.14.99.21 go-plus.json luciferase (Latia luciferin)|Latia luciferin monooxygenase (demethylating)|Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating) http://purl.obolibrary.org/obo/GO_0047098 GO:0072053 biolink:BiologicalProcess renal inner medulla development The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney. go-plus.json inner renal medulla development http://purl.obolibrary.org/obo/GO_0072053 GO:0047097 biolink:MolecularActivity phylloquinone monooxygenase (2,3-epoxidizing) activity Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O. RHEA:16745|MetaCyc:1.14.99.20-RXN|KEGG_REACTION:R03510|EC:1.14.99.20 go-plus.json vitamin K 2,3-epoxidase activity|phylloquinone epoxidase activity|vitamin K1 epoxidase activity|phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)|vitamin K epoxidase activity http://purl.obolibrary.org/obo/GO_0047097 GO:0072052 biolink:BiologicalProcess juxtaglomerulus cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072052 GO:0047096 biolink:MolecularActivity androst-4-ene-3,17-dione monooxygenase activity Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone. KEGG_REACTION:R01833|MetaCyc:1.14.99.12-RXN|RHEA:22696|EC:1.14.99.12 go-plus.json androstenedione monooxygenase activity|androst-4-ene-3,17-dione hydroxylase activity|androst-4-ene-3,17-dione 17-oxidoreductase activity|4-androstene-3,17-dione monooxygenase activity|androstene-3,17-dione hydroxylase activity|androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing) http://purl.obolibrary.org/obo/GO_0047096 GO:0072051 biolink:BiologicalProcess juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function. go-plus.json http://purl.obolibrary.org/obo/GO_0072051 GO:0047095 biolink:MolecularActivity 2-hydroxycyclohexanone 2-monooxygenase activity Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+). MetaCyc:1.14.13.66-RXN|RHEA:33283|KEGG_REACTION:R03281|EC:1.14.13.66 go-plus.json 2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing) http://purl.obolibrary.org/obo/GO_0047095 GO:0047094 biolink:MolecularActivity 3-hydroxyphenylacetate 6-hydroxylase activity Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate. MetaCyc:1.14.13.63-RXN|EC:1.14.13.63 go-plus.json 3-hydroxyphenylacetate 6-monooxygenase activity|3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating) http://purl.obolibrary.org/obo/GO_0047094 GO:0072050 biolink:BiologicalProcess S-shaped body morphogenesis The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072050 GO:0047093 biolink:MolecularActivity 4-hydroxyquinoline 3-monooxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol. MetaCyc:1.14.13.62-RXN|RHEA:19325|KEGG_REACTION:R05154|EC:1.14.13.62 go-plus.json 1-H-4-oxoquinoline 3-monooxygenase activity|quinolin-4(1H)-one 3-monooxygenase activity|quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating) http://purl.obolibrary.org/obo/GO_0047093 DDANAT:0000110 biolink:OntologyClass basal region Region of the early pseudoplasmodium located at the closest to the substratum composed of pstB cells. go-plus.json base http://purl.obolibrary.org/obo/DDANAT_0000110 CHEBI:59062 biolink:ChemicalSubstance polymyxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59062 GO:0072059 biolink:BiologicalProcess cortical collecting duct development The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0072059 GO:0072058 biolink:BiologicalProcess outer stripe development The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region. go-plus.json http://purl.obolibrary.org/obo/GO_0072058 GO:0072057 biolink:BiologicalProcess inner stripe development The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle. go-plus.json http://purl.obolibrary.org/obo/GO_0072057 GO:0072045 biolink:BiologicalProcess convergent extension involved in nephron morphogenesis The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072045 GO:0072044 biolink:BiologicalProcess collecting duct development The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0072044 GO:0072043 biolink:BiologicalProcess regulation of pre-tubular aggregate formation by cell-cell signaling Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney. go-plus.json regulation of pre-tubular aggregate formation by cell-cell signalling http://purl.obolibrary.org/obo/GO_0072043 GO:0072042 biolink:BiologicalProcess regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072042 GO:0072041 biolink:BiologicalProcess positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. go-plus.json positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072041 GO:0072040 biolink:BiologicalProcess negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. go-plus.json negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072040 DDANAT:0000101 biolink:OntologyClass prestalk AB core region of the tipped mound Cone-shaped area of the prestalk zone of the tipped mound that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. go-plus.json pstAB region|prestalk AB region of the tipped mound http://purl.obolibrary.org/obo/DDANAT_0000101 DDANAT:0000100 biolink:OntologyClass prestalk A region of the tipped mound Anterior-most region of the prestalk zone of the tipped mound characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). go-plus.json pstA region of the tipped mound http://purl.obolibrary.org/obo/DDANAT_0000100 NCBITaxon:72293 biolink:OrganismalEntity Helicobacteraceae go-plus.json Helicobacter group http://purl.obolibrary.org/obo/NCBITaxon_72293 GO:0072049 biolink:BiologicalProcess comma-shaped body morphogenesis The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072049 GO:0072048 biolink:BiologicalProcess renal system pattern specification Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system. go-plus.json renal system pattern formation http://purl.obolibrary.org/obo/GO_0072048 GO:0072047 biolink:BiologicalProcess proximal/distal pattern formation involved in nephron development The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end). go-plus.json proximal/distal nephron patterning|proximal-distal pattern formation involved in nephron development http://purl.obolibrary.org/obo/GO_0072047 GO:0072046 biolink:BiologicalProcess establishment of planar polarity involved in nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron. go-plus.json establishment of planar cell polarity involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072046 GO:0072078 biolink:BiologicalProcess nephron tubule morphogenesis The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072078 GO:0072077 biolink:BiologicalProcess renal vesicle morphogenesis The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072077 GO:0072076 biolink:BiologicalProcess nephrogenic mesenchyme development The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072076 GO:0072075 biolink:BiologicalProcess metanephric mesenchyme development The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072075 GO:0072074 biolink:BiologicalProcess kidney mesenchyme development The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072074 GO:0072073 biolink:BiologicalProcess kidney epithelium development The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072073 GO:0072072 biolink:BiologicalProcess kidney stroma development The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072072 GO:0072071 biolink:BiologicalProcess kidney interstitial fibroblast differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state. go-plus.json kidney interstitial cell differentiation http://purl.obolibrary.org/obo/GO_0072071 GO:0072070 biolink:BiologicalProcess loop of Henle development The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. go-plus.json intermediate tubule development http://purl.obolibrary.org/obo/GO_0072070 CHEBI:132746 biolink:ChemicalSubstance N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132746 CHEBI:132747 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132747 CHEBI:132749 biolink:ChemicalSubstance (S)-nandinine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132749 chebi_ph7_3 CHEBI:132740 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132740 CHEBI:132742 biolink:ChemicalSubstance lysophosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132742 GO:0072079 biolink:BiologicalProcess nephron tubule formation The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072079 GO:0072067 biolink:BiologicalProcess early distal convoluted tubule development The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive. go-plus.json http://purl.obolibrary.org/obo/GO_0072067 GO:0072066 biolink:BiologicalProcess prebend segment development The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. go-plus.json http://purl.obolibrary.org/obo/GO_0072066 GO:0072065 biolink:BiologicalProcess long descending thin limb bend development The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment. go-plus.json http://purl.obolibrary.org/obo/GO_0072065 GO:0072064 biolink:BiologicalProcess long descending thin limb development The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. go-plus.json http://purl.obolibrary.org/obo/GO_0072064 GO:0072063 biolink:BiologicalProcess short descending thin limb development The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0072063 GO:0072062 biolink:BiologicalProcess proximal convoluted tubule segment 1 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state. go-plus.json S1 cell differentiation http://purl.obolibrary.org/obo/GO_0072062 GO:0072061 biolink:BiologicalProcess inner medullary collecting duct development The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. go-plus.json http://purl.obolibrary.org/obo/GO_0072061 GO:0072060 biolink:BiologicalProcess outer medullary collecting duct development The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. go-plus.json http://purl.obolibrary.org/obo/GO_0072060 CHEBI:132750 biolink:ChemicalSubstance 2-methylbutan-2-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132750 chebi_ph7_3 CHEBI:132752 biolink:ChemicalSubstance 3-hydroxy-3-methylbut-1-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_132752 chebi_ph7_3 CHEBI:132755 biolink:ChemicalSubstance triethanolammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_132755 chebi_ph7_3 GO:0072069 biolink:BiologicalProcess DCT cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state. go-plus.json distal convoluted tubule cell differentiation http://purl.obolibrary.org/obo/GO_0072069 GO:0072068 biolink:BiologicalProcess late distal convoluted tubule development The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. go-plus.json http://purl.obolibrary.org/obo/GO_0072068 CHEBI:50699 biolink:ChemicalSubstance oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50699 GO:0072099 biolink:BiologicalProcess anterior/posterior pattern specification involved in ureteric bud development The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. go-plus.json ureteric bud anterior/posterior pattern formation http://purl.obolibrary.org/obo/GO_0072099 GO:0072098 biolink:BiologicalProcess anterior/posterior pattern specification involved in kidney development The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. go-plus.json anterior/posterior pattern formation involved in kidney development|kidney anterior/posterior pattern formation|kidney anterior/posterior pattern specification http://purl.obolibrary.org/obo/GO_0072098 GO:0072097 biolink:BiologicalProcess negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis. go-plus.json negative regulation of branch elongation involved in ureteric bud branching by BMP signalling pathway http://purl.obolibrary.org/obo/GO_0072097 GO:0072096 biolink:BiologicalProcess negative regulation of branch elongation involved in ureteric bud branching Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis. go-plus.json http://purl.obolibrary.org/obo/GO_0072096 GO:0072095 biolink:BiologicalProcess regulation of branch elongation involved in ureteric bud branching Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis. go-plus.json http://purl.obolibrary.org/obo/GO_0072095 GO:0072094 biolink:BiologicalProcess metanephric renal vesicle induction Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle. go-plus.json positive regulation of metanephros formation http://purl.obolibrary.org/obo/GO_0072094 GO:0072093 biolink:BiologicalProcess metanephric renal vesicle formation The developmental process pertaining to the initial formation of the metanephros. go-plus.json metanephros formation http://purl.obolibrary.org/obo/GO_0072093 GO:0072092 biolink:BiologicalProcess ureteric bud invasion The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072092 GO:0072091 biolink:BiologicalProcess regulation of stem cell proliferation Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072091 GO:0072090 biolink:BiologicalProcess mesenchymal stem cell proliferation involved in nephron morphogenesis The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072090 CHEBI:132725 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]glycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132725 CHEBI:132727 biolink:ChemicalSubstance 11a-hydroxytetracycline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_132727 chebi_ph7_3 CHEBI:132722 biolink:ChemicalSubstance N-arachidonoyl-gamma-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132722 CHEBI:50691 biolink:ChemicalSubstance abortifacient go-plus.json http://purl.obolibrary.org/obo/CHEBI_50691 CHEBI:50695 biolink:ChemicalSubstance monobactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_50695 CHEBI:50694 biolink:ChemicalSubstance minocycline go-plus.json http://purl.obolibrary.org/obo/CHEBI_50694 GO:0072089 biolink:BiologicalProcess stem cell proliferation The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072089 GO:0072088 biolink:BiologicalProcess nephron epithelium morphogenesis The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072088 GO:0072087 biolink:BiologicalProcess renal vesicle development The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072087 GO:0072086 biolink:BiologicalProcess specification of loop of Henle identity The process in which the loop of Henle of the kidney nephron acquires its identity. go-plus.json specification of intermediate tubule identity http://purl.obolibrary.org/obo/GO_0072086 GO:0072085 biolink:BiologicalProcess specification of connecting tubule identity The process in which the connecting tubule of the kidney nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072085 GO:0072084 biolink:BiologicalProcess specification of distal tubule identity The process in which the distal tubule of the kidney nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072084 GO:0072083 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072083 GO:0072082 biolink:BiologicalProcess specification of proximal tubule identity The process in which the proximal tubule of the kidney nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072082 CHEBI:50689 biolink:ChemicalSubstance reproductive control drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_50689 GO:0072081 biolink:BiologicalProcess specification of nephron tubule identity The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072081 CHEBI:132735 biolink:ChemicalSubstance 4-hydroxy-6-methylpretetramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132735 GO:0072080 biolink:BiologicalProcess nephron tubule development The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072080 CHEBI:132734 biolink:ChemicalSubstance 6-methylpretetramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132734 chebi_ph7_3 CHEBI:132737 biolink:ChemicalSubstance 4-de(dimethylamino)-4-oxoanhydrotetracycline(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132737 chebi_ph7_3 CHEBI:132736 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132736 CHEBI:132738 biolink:ChemicalSubstance N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]glycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132738 UBERON:2000940 biolink:AnatomicalEntity posterior lateral line neuromast Neuromast that is part of the posterior lateral line. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.) go-plus.json neuromasts posterior|neuromast posterior http://purl.obolibrary.org/obo/UBERON_2000940 CHEBI:50680 biolink:ChemicalSubstance methotrexate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50680 CHEBI:35063 biolink:ChemicalSubstance alpha-zeacarotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35063 chebi_ph7_3 CHEBI:50684 biolink:ChemicalSubstance cross-linking reagent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50684 CHEBI:50683 biolink:ChemicalSubstance EC 1.5.1.3 (dihydrofolate reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50683 CHEBI:8005 biolink:ChemicalSubstance peptidoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_8005 CHEBI:50681 biolink:ChemicalSubstance methotrexate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50681 chebi_ph7_3 CHEBI:74600 biolink:ChemicalSubstance (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74600 CHEBI:50675 biolink:ChemicalSubstance beta-D-glucosaminyl-(1->4)-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50675 CHEBI:74602 biolink:ChemicalSubstance (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74602 CHEBI:74601 biolink:ChemicalSubstance (16Z,19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74601 CHEBI:50674 biolink:ChemicalSubstance chitobioses go-plus.json http://purl.obolibrary.org/obo/CHEBI_50674 CHEBI:74604 biolink:ChemicalSubstance guanosine 2'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74604 chebi_ph7_3 CHEBI:74603 biolink:ChemicalSubstance (18Z,21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74603 CHEBI:74606 biolink:ChemicalSubstance (11Z,14Z,17Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74606 CHEBI:74608 biolink:ChemicalSubstance (13Z,16Z,19Z)-3-oxodocosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74608 CHEBI:74609 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z)-3-oxodocosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74609 CHEBI:132708 biolink:ChemicalSubstance N-arachidonoyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132708 CHEBI:59002 biolink:ChemicalSubstance N-arachidonoylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59002 chebi_ph7_3 CHEBI:35032 biolink:ChemicalSubstance trioxilin B3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_35032 CHEBI:50671 biolink:ChemicalSubstance antithyroid drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_50671 CHEBI:74610 biolink:ChemicalSubstance (6Z)-hexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74610 CHEBI:74617 biolink:ChemicalSubstance 1-oleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74617 chebi_ph7_3 CHEBI:50667 biolink:ChemicalSubstance mercaptopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50667 chebi_ph7_3 CHEBI:74619 biolink:ChemicalSubstance aclacinomycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_74619 CHEBI:132717 biolink:ChemicalSubstance bleaching agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_132717 NCBITaxon:72274 biolink:OrganismalEntity Pseudomonadales go-plus.json gamma-3 proteobacteria|Pseudomonaceae/Moraxellaceae group http://purl.obolibrary.org/obo/NCBITaxon_72274 CHEBI:50661 biolink:ChemicalSubstance loliose go-plus.json http://purl.obolibrary.org/obo/CHEBI_50661 chebi_ph7_3 CHEBI:50660 biolink:ChemicalSubstance 7-deazaguanine ribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_50660 GO:0047012 biolink:MolecularActivity sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one. MetaCyc:1.1.1.170-RXN|EC:1.1.1.170 go-plus.json 3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|sterol 4-alpha-carboxylic decarboxylase activity|3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047012 GO:0023045 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023045 GO:0047011 biolink:MolecularActivity 2-dehydropantolactone reductase (A-specific) activity Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+. EC:1.1.1.168|MetaCyc:1.1.1.168-RXN go-plus.json (R)-pantolactone:NADP+ oxidoreductase (A-specific)|2-oxopantoyl lactone reductase|ketopantoyl lactone reductase activity|2-dehydropantoyl-lactone reductase (A-specific) activity|2-ketopantoyl lactone reductase activity http://purl.obolibrary.org/obo/GO_0047011 GO:0023044 biolink:BiologicalProcess obsolete signaling via chemical mediator OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator. go-plus.json signalling via chemical mediator|signaling via chemical mediator http://purl.obolibrary.org/obo/GO_0023044 GO:0047010 biolink:MolecularActivity hydroxycyclohexanecarboxylate dehydrogenase activity Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH. MetaCyc:1.1.1.166-RXN|EC:1.1.1.166|RHEA:10516|KEGG_REACTION:R05315 go-plus.json (-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity|(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity|dihydroxycyclohexanecarboxylate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047010 GO:0023047 biolink:BiologicalProcess obsolete signal initiation by chemical mediator OBSOLETE. The process in which a chemical signal causes activation of a receptor. go-plus.json signal initiation by chemical mediator http://purl.obolibrary.org/obo/GO_0023047 GO:0023046 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023046 GO:0023049 biolink:BiologicalProcess obsolete signal initiation by protein/peptide mediator OBSOLETE. The process in which a protein/peptide signal causes activation of a receptor. go-plus.json signal initiation by protein/peptide mediator http://purl.obolibrary.org/obo/GO_0023049 GO:0023048 biolink:BiologicalProcess obsolete signal initiation by lipid mediator OBSOLETE. The process in which a lipid signal causes activation of a receptor. go-plus.json signal initiation by lipid mediator http://purl.obolibrary.org/obo/GO_0023048 CL:0002306 biolink:Cell epithelial cell of proximal tubule An epithelial cell of the proximal tubule of the kidney. go-plus.json kidney proximal tubule epithelial cell http://purl.obolibrary.org/obo/CL_0002306 GO:0047019 biolink:MolecularActivity indole-3-acetaldehyde reductase (NADPH) activity Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH. KEGG_REACTION:R02680|RHEA:17037|MetaCyc:1.1.1.191-RXN|EC:1.1.1.191 go-plus.json (indol-3-yl)ethanol:NADP+ oxidoreductase activity|indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|indole-3-ethanol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047019 CL:0002305 biolink:Cell epithelial cell of distal tubule An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH. go-plus.json kidney distal tubule epithelial cell http://purl.obolibrary.org/obo/CL_0002305 GO:0047018 biolink:MolecularActivity indole-3-acetaldehyde reductase (NADH) activity Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH. MetaCyc:1.1.1.190-RXN|EC:1.1.1.190|KEGG_REACTION:R02679|RHEA:14873 go-plus.json (indol-3-yl)ethanol:NAD+ oxidoreductase activity|indole-3-ethanol:NAD+ oxidoreductase activity|indoleacetaldehyde reductase activity http://purl.obolibrary.org/obo/GO_0047018 GO:0047017 biolink:MolecularActivity prostaglandin-F synthase activity Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate. RHEA:10140|MetaCyc:1.1.1.188-RXN|EC:1.1.1.188 go-plus.json PGD2 11-ketoreductase activity|reductase, 15-hydroxy-11-oxoprostaglandin|prostaglandin 11-ketoreductase activity|prostaglandin-D(2) 11-ketoreductase activity|PGF synthetase activity|prostaglandin-D2 11-reductase activity|prostaglandin F synthetase activity|prostaglandin-D2 ketoreductase activity|prostaglandin 11-keto reductase activity|prostaglandin-D2 11-ketoreductase activity|prostaglandin D2-ketoreductase activity|PGD(2) 11-ketoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity|prostaglandin-F synthetase activity|prostaglandin F synthase activity|PGF2alpha synthetase activity|prostaglandin-D(2) 11-reductase activity|prostaglandin-D(2) ketoreductase activity|NADPH-dependent prostaglandin D2 11-keto reductase activity|synthetase, prostaglandin F2alpha http://purl.obolibrary.org/obo/GO_0047017 GO:0047016 biolink:MolecularActivity cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one. MetaCyc:1.1.1.181-RXN|EC:1.1.1.181|RHEA:11896 go-plus.json cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity|cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047016 GO:0023041 biolink:BiologicalProcess neuronal signal transduction The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular. go-plus.json http://purl.obolibrary.org/obo/GO_0023041 GO:0047015 biolink:MolecularActivity 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA. MetaCyc:1.1.1.178-RXN|RHEA:13281|EC:1.1.1.178 go-plus.json 2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity|2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity|(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity|2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047015 GO:0023040 biolink:BiologicalProcess obsolete signaling via ionic flux OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux. go-plus.json signaling via ionic flux|signalling via ionic flux http://purl.obolibrary.org/obo/GO_0023040 GO:0047014 biolink:MolecularActivity glycerol-3-phosphate 1-dehydrogenase [NADP+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH. RHEA:19773|MetaCyc:1.1.1.177-RXN|EC:1.1.1.177|KEGG_REACTION:R00845 go-plus.json L-glycerol 3-phosphate:NADP oxidoreductase activity|sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity|glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|glycerin-3-phosphate dehydrogenase activity|NADPH-dependent glycerin-3-phosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047014 GO:0023043 biolink:BiologicalProcess obsolete signaling via lipid mediator OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator. go-plus.json signaling via lipid mediator|signalling via lipid mediator http://purl.obolibrary.org/obo/GO_0023043 GO:0047013 biolink:MolecularActivity cholate 12-alpha dehydrogenase activity Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH. MetaCyc:1.1.1.176-RXN|EC:1.1.1.176|RHEA:14129|KEGG_REACTION:R02793 go-plus.json 12-alpha-hydroxysteroid dehydrogenase activity|NADP-12alpha-hydroxysteroid dehydrogenase activity|NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity|12alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxy steroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047013 GO:0023042 biolink:BiologicalProcess obsolete signaling via protein/peptide mediator OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator. go-plus.json signaling via protein/peptide mediator|signalling via protein/peptide mediator http://purl.obolibrary.org/obo/GO_0023042 GO:0047023 biolink:MolecularActivity androsterone dehydrogenase activity Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. MetaCyc:1.1.1.209-RXN|EC:1.1.1.209 go-plus.json 3(17)alpha-hydroxysteroid dehydrogenase activity|3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity|3(or 17)-alpha-hydroxysteroid dehydrogenase activity|3(or 17)alpha-hydroxysteroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047023 GO:0023034 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023034 CHEBI:142163 biolink:ChemicalSubstance 24G7 epitope go-plus.json http://purl.obolibrary.org/obo/CHEBI_142163 GO:0023033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023033 GO:0047022 biolink:MolecularActivity 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid. Wikipedia:7beta-hydroxysteroid_dehydrogenase_(NADP+)|RHEA:20233|MetaCyc:1.1.1.201-RXN|EC:1.1.1.201 go-plus.json NADP-dependent 7beta-hydroxysteroid dehydrogenase activity|NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity|7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity|7beta-hydroxysteroid dehydrogenase (NADP+) http://purl.obolibrary.org/obo/GO_0047022 GO:0023036 biolink:BiologicalProcess obsolete initiation of signal transduction OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change. go-plus.json signal reception|initiation of signal transduction http://purl.obolibrary.org/obo/GO_0023036 GO:0047021 biolink:MolecularActivity 15-hydroxyprostaglandin dehydrogenase (NADP+) activity Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH. RHEA:11636|KEGG_REACTION:R04552|MetaCyc:1.1.1.197-RXN|EC:1.1.1.197 go-plus.json type II 15-hydroxyprostaglandin dehydrogenase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|NADP-linked 15-hydroxyprostaglandin dehydrogenase|(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity|NADP-specific 15-hydroxyprostaglandin dehydrogenase http://purl.obolibrary.org/obo/GO_0047021 GO:0047020 biolink:MolecularActivity 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate. RHEA:20744|MetaCyc:1.1.1.196-RXN|EC:1.1.1.196 go-plus.json 15-hydroxy PGD2 dehydrogenase activity|prostaglandin-D 15-dehydrogenase (NADP+) activity|NADP-linked prostaglandin D2 dehydrogenase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|prostaglandin-D 15-dehydrogenase (NADP(+)) activity|prostaglandin-D 15-dehydrogenase (NADP)|15-hydroxyprostaglandin dehydrogenase (NADP)|dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)|prostaglandin D2 dehydrogenase activity|dehydrogenase, prostaglandin D2|NADP-linked 15-hydroxyprostaglandin dehydrogenase|NADP-PGD2 dehydrogenase activity|NADP-specific 15-hydroxyprostaglandin dehydrogenase|(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047020 GO:0023035 biolink:BiologicalProcess CD40 signaling pathway A series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json CD40 signalling pathway http://purl.obolibrary.org/obo/GO_0023035 GO:0023038 biolink:BiologicalProcess obsolete signal initiation by diffusible mediator OBSOLETE. The process in which a diffusible signal causes activation of a receptor. go-plus.json signal initiation by diffusible mediator http://purl.obolibrary.org/obo/GO_0023038 GO:0023037 biolink:BiologicalProcess obsolete signal initiation by light OBSOLETE. The process in which a light signal causes activation of a receptor. go-plus.json signal initiation by light http://purl.obolibrary.org/obo/GO_0023037 GO:0023039 biolink:BiologicalProcess obsolete signal initiation by physical damage OBSOLETE. The process in which a physical damage signal causes activation of a receptor. go-plus.json signal initiation by physical damage http://purl.obolibrary.org/obo/GO_0023039 GO:0047029 biolink:MolecularActivity (R)-4-hydroxyphenyllactate dehydrogenase (NADPH) activity Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate. MetaCyc:RXN-7632|RHEA:52692|EC:1.1.1.110|https://github.com/geneontology/go-ontology/issues/21412 go-plus.json phenylpyruvate reductase activity|aromatic 2-oxoacid reductase activity|hydroxyphenylpyruvate reductase activity http://purl.obolibrary.org/obo/GO_0047029 CL:0002319 biolink:Cell neural cell A cell that is part of the nervous system. go-plus.json http://purl.obolibrary.org/obo/CL_0002319 GO:0047028 biolink:MolecularActivity 6-pyruvoyltetrahydropterin 2'-reductase activity Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin. RHEA:11772|MetaCyc:1.1.1.220-RXN|EC:1.1.1.220 go-plus.json 6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity|6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity|6PPH4(2'-oxo) reductase activity|6-pyruvoyl-tetrahydropterin 2'-reductase activity|6-pyruvoyltetrahydropterin reductase activity|pyruvoyl-tetrahydropterin reductase activity http://purl.obolibrary.org/obo/GO_0047028 GO:0023030 biolink:MolecularActivity MHC class Ib protein binding, via antigen binding groove Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove. go-plus.json http://purl.obolibrary.org/obo/GO_0023030 GO:0047027 biolink:MolecularActivity benzyl-2-methyl-hydroxybutyrate dehydrogenase activity Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH. RHEA:16405|MetaCyc:1.1.1.217-RXN|EC:1.1.1.217|KEGG_REACTION:R04370 go-plus.json benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity|benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047027 GO:0047026 biolink:MolecularActivity androsterone dehydrogenase (A-specific) activity Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+. MetaCyc:1.1.1.213-RXN|Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(A-specific)|EC:1.1.1.213 go-plus.json 3alpha-hydroxysteroid dehydrogenase (A-specific)|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)|3-alpha-hydroxysteroid dehydrogenase (A-specific) activity http://purl.obolibrary.org/obo/GO_0047026 GO:0023032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023032 GO:0047025 biolink:MolecularActivity 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein]. RHEA:19913|MetaCyc:1.1.1.212-RXN|EC:1.1.1.212 go-plus.json 3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity|3-oxoacyl-ACP reductase (NADH) activity|3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity|3-oxoacyl-acyl-carrier-protein reductase (NADH) http://purl.obolibrary.org/obo/GO_0047025 GO:0023031 biolink:MolecularActivity MHC class Ib protein binding, via lateral surface Binding to a major histocompatibility complex class Ib molecules via the lateral surface. go-plus.json http://purl.obolibrary.org/obo/GO_0023031 GO:0047024 biolink:MolecularActivity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH. KEGG_REACTION:R04344|MetaCyc:1.1.1.210-RXN|RHEA:16297|EC:1.1.1.210 go-plus.json progesterone reductase activity|3beta(or 20alpha)-hydroxysteroid dehydrogenase activity|3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity|3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity|3-beta-HSD activity|3beta,20alpha-hydroxysteroid oxidoreductase activity|dehydrogenase, 3beta,20alpha-hydroxy steroid http://purl.obolibrary.org/obo/GO_0047024 CL:0002313 biolink:Cell endocrine-paracrine cell of prostate gland An ecto-epithelial cell of the prostate gland that secretes hormones. go-plus.json glandular cell of prostate|neuro-epithelial cell of prostate gland http://purl.obolibrary.org/obo/CL_0002313 GO:0047034 biolink:MolecularActivity 15-hydroxyicosatetraenoate dehydrogenase activity Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate. EC:1.1.1.232|Reactome:R-HSA-2161789|MetaCyc:1.1.1.232-RXN go-plus.json (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity|15-hydroxyeicosatetraenoate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047034 GO:0023023 biolink:MolecularActivity MHC protein complex binding Binding to a major histocompatibility complex. go-plus.json http://purl.obolibrary.org/obo/GO_0023023 GO:0023022 biolink:BiologicalProcess termination of T cell signal transduction The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated. go-plus.json http://purl.obolibrary.org/obo/GO_0023022 GO:0047033 biolink:MolecularActivity 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH. EC:1.1.1.231|RHEA:21420|KEGG_REACTION:R03520|MetaCyc:1.1.1.231-RXN go-plus.json PG I2 dehydrogenase activity|prostacyclin dehydrogenase activity|NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity|(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity|NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047033 GO:0047032 biolink:MolecularActivity 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH. EC:1.1.1.230|RHEA:20816|KEGG_REACTION:R04099|MetaCyc:1.1.1.230-RXN go-plus.json 3alpha-hydroxyglycyrrhetinate dehydrogenase activity|3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047032 GO:0023025 biolink:MolecularActivity MHC class Ib protein complex binding Binding to a class Ib major histocompatibility complex. go-plus.json http://purl.obolibrary.org/obo/GO_0023025 GO:0023024 biolink:MolecularActivity MHC class I protein complex binding Binding to a class I major histocompatibility complex. go-plus.json http://purl.obolibrary.org/obo/GO_0023024 GO:0047031 biolink:MolecularActivity diethyl 2-methyl-3-oxosuccinate reductase activity Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH. RHEA:21008|MetaCyc:1.1.1.229-RXN|KEGG_REACTION:R04387|EC:1.1.1.229 go-plus.json diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047031 GO:0047030 biolink:MolecularActivity 4-hydroxycyclohexanecarboxylate dehydrogenase activity Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH. KEGG_REACTION:R04307|RHEA:17429|MetaCyc:1.1.1.226-RXN|EC:1.1.1.226 go-plus.json trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity|trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047030 GO:0023027 biolink:MolecularActivity MHC class I protein binding, via antigen binding groove Binding to a major histocompatibility complex class I molecules via the antigen binding groove. go-plus.json http://purl.obolibrary.org/obo/GO_0023027 GO:0023026 biolink:MolecularActivity MHC class II protein complex binding Binding to a class II major histocompatibility complex. go-plus.json http://purl.obolibrary.org/obo/GO_0023026 GO:0023029 biolink:MolecularActivity MHC class Ib protein binding Binding to a major histocompatibility complex class Ib molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0023029 GO:0023028 biolink:MolecularActivity MHC class I protein binding, via lateral surface Binding to a major histocompatibility complex class I molecules via the lateral surface. go-plus.json http://purl.obolibrary.org/obo/GO_0023028 GO:0047039 biolink:MolecularActivity tetrahydroxynaphthalene reductase activity Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol. MetaCyc:1.1.1.252-RXN|EC:1.1.1.252|RHEA:21908 go-plus.json T4HN reductase activity|scytalone:NADP+ delta5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047039 GO:0047038 biolink:MolecularActivity D-arabinitol 2-dehydrogenase activity Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH. MetaCyc:1.1.1.250-RXN|EC:1.1.1.250|RHEA:17389|KEGG_REACTION:R07134 go-plus.json D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)|D-arabinitol 2-dehydrogenase (ribulose-forming) activity http://purl.obolibrary.org/obo/GO_0047038 GO:0047037 biolink:MolecularActivity salutaridine reductase (NADPH) activity Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine. RHEA:10108|KEGG_REACTION:R04697|MetaCyc:1.1.1.248-RXN|EC:1.1.1.248 go-plus.json salutaridinol:NADP+ 7-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047037 GO:0047036 biolink:MolecularActivity codeinone reductase (NADPH) activity Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH. EC:1.1.1.247|RHEA:19209|KEGG_REACTION:R05124|MetaCyc:1.1.1.247-RXN go-plus.json codeine:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047036 GO:0023021 biolink:BiologicalProcess termination of signal transduction The signaling process in which signal transduction is brought to an end rather than being reversibly modulated. go-plus.json http://purl.obolibrary.org/obo/GO_0023021 GO:0047035 biolink:MolecularActivity testosterone dehydrogenase (NAD+) activity Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH. MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN|RHEA:14929|KEGG_REACTION:R01836|Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)|MetaCyc:1.1.1.239-RXN|EC:1.1.1.239 go-plus.json 17-beta-HSD activity|17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity|17beta-HSD|testosterone 17-beta-dehydrogenase (NAD+) activity|3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity|3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)|testosterone 17b-dehydrogenase activity|3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity|testosterone 17beta-dehydrogenase activity|3alpha(17beta)-HSD|3alpha,17beta-hydroxy steroid dehydrogenase activity|17-ketoreductase activity http://purl.obolibrary.org/obo/GO_0047035 GO:0023020 biolink:BiologicalProcess obsolete regulation of gene expression as a consequence of T cell signal transmission OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another. go-plus.json regulation of gene expression as a consequence of T cell signal transmission http://purl.obolibrary.org/obo/GO_0023020 GO:0047045 biolink:MolecularActivity testosterone 17-beta-dehydrogenase (NADP+) activity Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione. RHEA:14981|Wikipedia:Testosterone_17beta-dehydrogenase_(NADP+)|MetaCyc:1.1.1.64-RXN|KEGG_REACTION:R01838|EC:1.1.1.64 go-plus.json NADP-dependent testosterone-17beta-oxidoreductase activity|17-ketoreductase activity|testosterone 17beta-dehydrogenase (NADP+)|17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047045 GO:0023012 biolink:BiologicalProcess obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling. go-plus.json initiation of T cell receptor signalling by binding of a MHC complex to T cell receptor|initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor http://purl.obolibrary.org/obo/GO_0023012 GO:0047044 biolink:MolecularActivity androstan-3-alpha,17-beta-diol dehydrogenase activity Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+. RHEA:22400|MetaCyc:1.1.1.53-RXN|EC:1.1.1.53 go-plus.json 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity|20beta-hydroxysteroid dehydrogenase activity|(R)-20-hydroxysteroid dehydrogenase activity|dehydrogenase, 20beta-hydroxy steroid|3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity|cortisone reductase activity|NADH-20beta-hydroxysteroid dehydrogenase activity|3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity|3alpha(or 20beta)-hydroxysteroid dehydrogenase activity|delta4-3-ketosteroid hydrogenase activity|20beta-HSD http://purl.obolibrary.org/obo/GO_0047044 GO:0023011 biolink:BiologicalProcess obsolete positive regulation of initiation of T cell receptor signaling OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the initiation of T cell receptor signaling. go-plus.json positive regulation of initiation of T cell receptor signaling|positive regulation of initiation of T cell receptor signalling http://purl.obolibrary.org/obo/GO_0023011 GO:0023014 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023014 GO:0047043 biolink:MolecularActivity 3-alpha-hydroxycholanate dehydrogenase activity Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH. KEGG_REACTION:R04139|RHEA:19585|MetaCyc:1.1.1.52-RXN|EC:1.1.1.52 go-plus.json 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity|3alpha-hydroxycholanate dehydrogenase activity|alpha-hydroxy-cholanate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047043 GO:0047042 biolink:MolecularActivity androsterone dehydrogenase (B-specific) activity Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+. EC:1.1.1.50|Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(B-specific)|MetaCyc:1.1.1.50-RXN go-plus.json 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity|hydroxyprostaglandin dehydrogenase activity|sterognost 3alpha|3alpha-hydroxysteroid oxidoreductase activity|3-alpha-HSD activity|3alpha-hydroxysteroid dehydrogenase (B-specific)|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)|3alpha-HSD http://purl.obolibrary.org/obo/GO_0047042 GO:0023013 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023013 GO:0023016 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023016 GO:0047041 biolink:MolecularActivity (S)-carnitine 3-dehydrogenase activity Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH. MetaCyc:1.1.1.254-RXN|EC:1.1.1.254|KEGG_REACTION:R01921|RHEA:11556 go-plus.json D-carnitine dehydrogenase activity|(S)-carnitine:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047041 GO:0023015 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0023015 GO:0047040 biolink:MolecularActivity pteridine reductase activity Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH. MetaCyc:1.1.1.253-RXN|KEGG_REACTION:R01812|EC:1.5.1.33|RHEA:19509 go-plus.json ptr1 activity|pteridine reductase 1 activity|PTR1|dihydrobiopterin reduction|5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047040 GO:0023018 biolink:BiologicalProcess obsolete T cell activation of signal transmission via diffusible molecule OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell. go-plus.json T cell activation of signal transmission via diffusible molecule http://purl.obolibrary.org/obo/GO_0023018 GO:0023017 biolink:BiologicalProcess obsolete signal transmission via diffusible molecule OBSOLETE. The process in which a signal is conveyed via a diffusible molecule. go-plus.json signaling via diffusible mediator|signal transmission via diffusible molecule http://purl.obolibrary.org/obo/GO_0023017 GO:0047049 biolink:MolecularActivity (R)-2-hydroxy-fatty acid dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH. KEGG_REACTION:R03021|MetaCyc:1.1.1.98-RXN|RHEA:15949|EC:1.1.1.98 go-plus.json 2-hydroxy fatty acid oxidase|(R)-2-hydroxy-fatty-acid dehydrogenase activity|(R)-2-hydroxystearate:NAD+ oxidoreductase activity|D-2-hydroxy fatty acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047049 GO:0047048 biolink:MolecularActivity 3-hydroxybenzyl-alcohol dehydrogenase activity Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH. EC:1.1.1.97|KEGG_REACTION:R04136|RHEA:22340|MetaCyc:1.1.1.97-RXN go-plus.json 3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity|m-hydroxybenzylalcohol dehydrogenase activity|m-hydroxybenzyl alcohol dehydrogenase activity|m-hydroxybenzyl alcohol (NADP) dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047048 GO:0047047 biolink:MolecularActivity oxaloglycolate reductase (decarboxylating) activity Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate. EC:1.1.1.92|MetaCyc:1.1.1.92-RXN go-plus.json D-glycerate:NAD(P)+ oxidoreductase (carboxylating) http://purl.obolibrary.org/obo/GO_0047047 GO:0023010 biolink:BiologicalProcess obsolete regulation of initiation of T cell receptor signaling OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling. go-plus.json regulation of initiation of T cell receptor signalling|regulation of initiation of T cell receptor signaling http://purl.obolibrary.org/obo/GO_0023010 GO:0047046 biolink:MolecularActivity homoisocitrate dehydrogenase activity Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate. MetaCyc:1.1.1.87-RXN|EC:1.1.1.87|RHEA:11900 go-plus.json (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)|3-carboxy-2-hydroxyadipate dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity|2-hydroxy-3-carboxyadipate dehydrogenase activity|homoisocitric dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)|(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)|(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity http://purl.obolibrary.org/obo/GO_0047046 GO:0023019 biolink:BiologicalProcess signal transduction involved in regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. go-plus.json regulation of gene expression as a consequence of signal transmission http://purl.obolibrary.org/obo/GO_0023019 CHEBI:8028 biolink:ChemicalSubstance perphenazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_8028 GO:0072012 biolink:BiologicalProcess glomerulus vasculature development The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. go-plus.json glomerulus capillary development http://purl.obolibrary.org/obo/GO_0072012 GO:0047056 biolink:MolecularActivity (S)-canadine synthase activity Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O. EC:1.14.19.68|RHEA:21456|KEGG_REACTION:R04400|MetaCyc:1.1.3.36-RXN go-plus.json (S)-tetrahydroberberine synthase activity|(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity http://purl.obolibrary.org/obo/GO_0047056 GO:0072011 biolink:BiologicalProcess glomerular endothelium development The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072011 GO:0047055 biolink:MolecularActivity salutaridine synthase activity Catalysis of the reaction: (R)-reticuline + [reduced NADPH--hemoprotein reductase] + O2 -> salutaridine + [oxidized NADPH--hemoprotein reductase] + 2 H2O. EC:1.14.19.67|RHEA:17713|KEGG_REACTION:R04696|MetaCyc:1.1.3.35-RXN go-plus.json (R)-reticuline oxidase (C-C phenol-coupling) activity http://purl.obolibrary.org/obo/GO_0047055 GO:0072010 biolink:BiologicalProcess glomerular epithelium development The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072010 GO:0023003 biolink:BiologicalProcess nuclear migration to the embryo sac center Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell. go-plus.json nuclear migration to the female gametophyte center|nucleus migration to the female gametophyte centre|nuclear migration to the megagametophyte centre|nuclear migration to the embryo sac centre|nucleus migration to the female gametophyte center|nuclear migration to the megagametophyte center|nuclear migration to the female gametophyte centre http://purl.obolibrary.org/obo/GO_0023003 GO:0047054 biolink:MolecularActivity berbamunine synthase activity Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 <=> berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O. EC:1.14.19.66|RHEA:23576|MetaCyc:1.1.3.34-RXN go-plus.json heme-thiolate http://purl.obolibrary.org/obo/GO_0047054 GO:0047053 biolink:MolecularActivity (S)-cheilanthifoline synthase activity Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-cheilanthifoline + [oxidized NADPH--hemoprotein reductase] + 2 H2O. MetaCyc:1.14.21.2-RXN|EC:1.14.19.65|KEGG_REACTION:R03834|RHEA:20485 go-plus.json (S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity|(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming) http://purl.obolibrary.org/obo/GO_0047053 GO:0023002 biolink:BiologicalProcess nuclear migration to embryo sac poles Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell. go-plus.json nuclear migration to megagametophyte poles|nucleus migration to female gametophyte poles|nucleus migration to megagametophyte poles|nuclear migration to female gametophyte poles|nucleus migration to embryo sac poles http://purl.obolibrary.org/obo/GO_0023002 CHEBI:8087 biolink:ChemicalSubstance N(2)-phenylacetylglutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_8087 GO:0047052 biolink:MolecularActivity (S)-stylopine synthase activity Catalysis of the reaction: (S)-cheilanthifoline + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-stylopine + [oxidized NADPH--hemoprotein reductase] + 2 H2O. EC:1.14.19.64|RHEA:13773|KEGG_REACTION:R04690|MetaCyc:1.1.3.32-RXN go-plus.json (S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)|(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity http://purl.obolibrary.org/obo/GO_0047052 GO:0023005 biolink:BiologicalProcess obsolete signal initiation by neurotransmitter OBSOLETE. The process in which a neurotransmitter signal causes activation of a receptor. go-plus.json signal initiation by neurotransmitter http://purl.obolibrary.org/obo/GO_0023005 GO:0023004 biolink:BiologicalProcess obsolete activation of dopamine receptor signaling pathway OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor. go-plus.json activation of dopamine receptor signalling pathway|activation of dopamine receptor signaling pathway|stimulation of dopamine receptor signaling pathway|initiation of dopamine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0023004 GO:0047051 biolink:MolecularActivity D-lactate dehydrogenase (cytochrome c-553) activity Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate. MetaCyc:1.1.2.5-RXN|RHEA:16465|EC:1.1.2.5 go-plus.json (R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047051 GO:0023007 biolink:BiologicalProcess obsolete ligand binding to T cell receptor OBSOLETE. Binding of a diffusible ligand to a T cell receptor as part of a signaling process. go-plus.json ligand binding to T cell receptor http://purl.obolibrary.org/obo/GO_0023007 GO:0047050 biolink:MolecularActivity (S)-2-hydroxy-fatty acid dehydrogenase activity Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH. EC:1.1.1.99|KEGG_REACTION:R03022|RHEA:11384|MetaCyc:1.1.1.99-RXN go-plus.json L-2-hydroxy fatty acid dehydrogenase activity|2-hydroxy fatty acid oxidase|(S)-2-hydroxy-fatty-acid dehydrogenase activity|dehydrogenase, L-2-hydroxy fatty acid|(S)-2-hydroxystearate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047050 GO:0023006 biolink:BiologicalProcess obsolete signal initiation by amino acid OBSOLETE. The process in which an amino acid signal causes activation of a receptor. go-plus.json signal initiation by amino acid http://purl.obolibrary.org/obo/GO_0023006 GO:0047059 biolink:MolecularActivity polyvinyl alcohol dehydrogenase (cytochrome) activity Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+. RHEA:20157|KEGG_REACTION:R03136|EC:1.1.2.6|MetaCyc:RXN-11316 go-plus.json polyvinyl-alcohol:(acceptor) oxidoreductase activity|polyvinyl alcohol:ferricytochrome-c oxidoreductase activity|polyvinyl-alcohol:acceptor oxidoreductase activity|PVA dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047059 GO:0047058 biolink:MolecularActivity vitamin-K-epoxide reductase (warfarin-insensitive) activity Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol. EC:1.17.4.5|RHEA:21560|MetaCyc:1.1.4.2-RXN go-plus.json vitamin K 2,3-epoxide reductase activity http://purl.obolibrary.org/obo/GO_0047058 GO:0047057 biolink:MolecularActivity vitamin-K-epoxide reductase (warfarin-sensitive) activity Catalysis of the reaction: phylloquinol + a protein with a disulfide bond = phylloquinone + a protein with reduced L-cysteine residues. Reactome:R-HSA-6806647|RHEA:57744|EC:1.17.4.4|MetaCyc:1.1.4.1-RXN|Reactome:R-HSA-159790 go-plus.json vitamin K1 epoxide reductase activity|phylloquinone epoxide reductase activity http://purl.obolibrary.org/obo/GO_0047057 GO:0023009 biolink:BiologicalProcess obsolete initiation of T cell receptor signaling OBSOLETE. The process in which a signal causes activation of T cell receptor signaling. go-plus.json initiation of T cell receptor signalling|initiation of T cell receptor signaling http://purl.obolibrary.org/obo/GO_0023009 GO:0072019 biolink:BiologicalProcess proximal convoluted tubule development The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072019 GO:0072018 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072018 GO:0072017 biolink:BiologicalProcess distal tubule development The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072017 GO:0072016 biolink:BiologicalProcess glomerular parietal epithelial cell development The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go-plus.json Bowman's capsule development http://purl.obolibrary.org/obo/GO_0072016 GO:0072015 biolink:BiologicalProcess glomerular visceral epithelial cell development The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. go-plus.json podocyte development http://purl.obolibrary.org/obo/GO_0072015 GO:0072014 biolink:BiologicalProcess proximal tubule development The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0072014 GO:0072013 biolink:BiologicalProcess glomus development The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment. go-plus.json pronephric glomus development http://purl.obolibrary.org/obo/GO_0072013 GO:0047067 biolink:MolecularActivity hydrogen:quinone oxidoreductase activity Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone. RHEA:18641|EC:1.12.5.1|MetaCyc:1.12.5.1-RXN|KEGG_REACTION:R02965 go-plus.json membrane-bound hydrogenase activity|hydrogen:menaquinone oxidoreductase activity|quinone-reactive Ni/Fe-hydrogenase activity|hydrogen-ubiquinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047067 GO:0072001 biolink:BiologicalProcess renal system development The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. go-plus.json urinary system development|urinary tract development http://purl.obolibrary.org/obo/GO_0072001 gocheck_do_not_annotate GO:0047066 biolink:MolecularActivity phospholipid-hydroperoxide glutathione peroxidase activity Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione. Reactome:R-HSA-9018868|RHEA:19057|Reactome:R-HSA-9018895|Reactome:R-HSA-9020271|Reactome:R-HSA-9020273|MetaCyc:1.11.1.12-RXN|EC:1.11.1.12 go-plus.json peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)|phospholipid hydroperoxide glutathione peroxidase activity|glutathione:lipid-hydroperoxide oxidoreductase activity|hydroperoxide glutathione peroxidase activity|peroxidation-inhibiting protein activity|PHGPX http://purl.obolibrary.org/obo/GO_0047066 GO:0072000 biolink:BiologicalProcess extracellular polysaccharide catabolic process involved in ascospore release from ascus The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus. go-plus.json ascus catabolic process|ascus endolysis|extracellular polysaccharide breakdown involved in ascospore release from ascus|extracellular polysaccharide degradation involved in ascospore release from ascus|extracellular polysaccharide catabolism involved in ascospore release from ascus http://purl.obolibrary.org/obo/GO_0072000 GO:0047065 biolink:MolecularActivity sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O. KEGG_REACTION:R00061|EC:1.21.3.5|MetaCyc:1.10.3.8-RXN|RHEA:22616 go-plus.json sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)|sulochrin oxidase activity http://purl.obolibrary.org/obo/GO_0047065 GO:0047064 biolink:MolecularActivity sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O. KEGG_REACTION:R00060|EC:1.21.3.4|RHEA:24092|MetaCyc:1.10.3.7-RXN go-plus.json sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)|sulochrin oxidase activity http://purl.obolibrary.org/obo/GO_0047064 GO:0047063 biolink:MolecularActivity obsolete L-ascorbate-cytochrome-b5 reductase activity OBSOLETE. Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate. RHEA:18677|EC:1.10.2.1|MetaCyc:1.10.2.1-RXN go-plus.json L-ascorbate:ferricytochrome-b5 oxidoreductase activity|ascorbate-cytochrome b5 reductase activity http://purl.obolibrary.org/obo/GO_0047063 GO:0047062 biolink:MolecularActivity trans-acenaphthene-1,2-diol dehydrogenase activity Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH. KEGG_REACTION:R04059|RHEA:22184|EC:1.10.1.1|MetaCyc:1.10.1.1-RXN go-plus.json trans-1,2-acenaphthenediol dehydrogenase activity|(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047062 GO:0047061 biolink:MolecularActivity glucose-fructose oxidoreductase activity Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone. MetaCyc:1.1.99.28-RXN|EC:1.1.99.28|RHEA:20637|KEGG_REACTION:R00874 go-plus.json D-glucose:D-fructose oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047061 GO:0047060 biolink:MolecularActivity (R)-pantolactone dehydrogenase (flavin) activity Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2). KEGG_REACTION:R03156|MetaCyc:1.1.99.27-RXN|EC:1.1.99.27|RHEA:21004 go-plus.json (R)-pantolactone:acceptor oxidoreductase (flavin-containing)|2-dehydropantoyl-lactone reductase (flavin) activity|2-dehydropantolactone reductase (flavin) activity|(R)-pantoyllactone dehydrogenase (flavin) activity http://purl.obolibrary.org/obo/GO_0047060 GO:0047069 biolink:MolecularActivity 7,8-dihydroxykynurenate 8,8a-dioxygenase activity Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+). MetaCyc:1.13.11.10-RXN|RHEA:23400|KEGG_REACTION:R03253|EC:1.13.11.10 go-plus.json 7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate oxygenase activity|7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity http://purl.obolibrary.org/obo/GO_0047069 GO:0047068 biolink:MolecularActivity N5,N10-methenyltetrahydromethanopterin hydrogenase activity Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+). KEGG_REACTION:R04455|MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN|EC:1.12.98.2|RHEA:20017 go-plus.json hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity|N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity|5,10-methenyltetrahydromethanopterin hydrogenase activity|H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|H2-dependent methylene-H4MPT dehydrogenase activity|H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|H(2)-dependent methylene-H(4)MPT dehydrogenase activity|hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity|nonmetal hydrogenase activity|hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047068 GO:0072009 biolink:BiologicalProcess nephron epithelium development The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072009 GO:0047070 biolink:MolecularActivity 3-carboxyethylcatechol 2,3-dioxygenase activity Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate. MetaCyc:1.13.11.16-RXN|RHEA:23840|EC:1.13.11.16 go-plus.json 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity|2,3-dihydroxy-beta-phenylpropionic dioxygenase activity|2,3-dihydroxy-beta-phenylpropionate oxygenase activity|3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0047070 GO:0072008 biolink:BiologicalProcess glomerular mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072008 GO:0072007 biolink:BiologicalProcess mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072007 GO:0072006 biolink:BiologicalProcess nephron development The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. go-plus.json nephrogenesis http://purl.obolibrary.org/obo/GO_0072006 GO:0072005 biolink:BiologicalProcess maintenance of kidney identity The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json maintenance of kidney anlage identity http://purl.obolibrary.org/obo/GO_0072005 GO:0072004 biolink:BiologicalProcess kidney field specification The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop. go-plus.json specification of kidney anlage http://purl.obolibrary.org/obo/GO_0072004 GO:0072003 biolink:BiologicalProcess kidney rudiment formation The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json kidney anlage formation http://purl.obolibrary.org/obo/GO_0072003 GO:0072002 biolink:BiologicalProcess Malpighian tubule development The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. go-plus.json http://purl.obolibrary.org/obo/GO_0072002 GO:0047078 biolink:MolecularActivity 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate. RHEA:17949|MetaCyc:1.13.11.47-RXN|EC:1.13.11.47 go-plus.json quinoline-3,4-diol 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity|3-hydroxy-4(1H)-one, 2,4-dioxygenase activity|3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity|(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity http://purl.obolibrary.org/obo/GO_0047078 GO:0072034 biolink:BiologicalProcess renal vesicle induction Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle. go-plus.json nephron induction|positive regulation of nephron formation http://purl.obolibrary.org/obo/GO_0072034 GO:0072033 biolink:BiologicalProcess renal vesicle formation The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. go-plus.json nephron epithelium formation http://purl.obolibrary.org/obo/GO_0072033 GO:0047077 biolink:MolecularActivity Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin. RHEA:10732|MetaCyc:1.13.12.7-RXN|EC:1.13.12.7 go-plus.json Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)|firefly luciferin luciferase activity|Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)|Photinus pyralis luciferase activity|firefly luciferase activity|luciferase activity|luciferase (firefly luciferin)|Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing) http://purl.obolibrary.org/obo/GO_0047077 GO:0072032 biolink:BiologicalProcess proximal convoluted tubule segment 2 development The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride. go-plus.json S2 development http://purl.obolibrary.org/obo/GO_0072032 GO:0047076 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047076 GO:0072031 biolink:BiologicalProcess proximal convoluted tubule segment 1 development The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. go-plus.json S1 development http://purl.obolibrary.org/obo/GO_0072031 GO:0047075 biolink:MolecularActivity 2,5-dihydroxypyridine 5,6-dioxygenase activity Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate. UM-BBD_reactionID:r1443|RHEA:27522|MetaCyc:1.13.11.9-RXN|EC:1.13.11.9 go-plus.json 2,5-dihydroxypyridine oxygenase activity|pyridine-2,5-diol dioxygenase activity|2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047075 GO:0072030 biolink:BiologicalProcess short nephron development The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. go-plus.json http://purl.obolibrary.org/obo/GO_0072030 GO:0047074 biolink:MolecularActivity 4-hydroxycatechol 1,2-dioxygenase activity Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate. MetaCyc:R308-RXN|RHEA:35595|EC:1.13.11.37|MetaCyc:RXN-10137 go-plus.json http://purl.obolibrary.org/obo/GO_0047074 GO:0047073 biolink:MolecularActivity 2,4'-dihydroxyacetophenone dioxygenase activity Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+). EC:1.13.11.41|KEGG_REACTION:R01305|RHEA:24416|UM-BBD_reactionID:r1410|MetaCyc:1.13.11.41-RXN go-plus.json (4-hydroxybenzoyl)methanol oxygenase activity|2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving) http://purl.obolibrary.org/obo/GO_0047073 GO:0047072 biolink:MolecularActivity 2,3-dihydroxybenzoate 2,3-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+). KEGG_REACTION:R01506|MetaCyc:1.13.11.28-RXN|RHEA:15369|EC:1.13.11.28 go-plus.json 2,3-dihydroxybenzoate 2,3-oxygenase activity|2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing) http://purl.obolibrary.org/obo/GO_0047072 GO:0047071 biolink:MolecularActivity 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+). MetaCyc:1.13.11.25-RXN|KEGG_REACTION:R04597|RHEA:21352|UM-BBD_reactionID:r1151|EC:1.13.11.25 go-plus.json steroid 4,5-dioxygenase activity|3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)|3-alkylcatechol 2,3-dioxygenase activity http://purl.obolibrary.org/obo/GO_0047071 CHEBI:142110 biolink:ChemicalSubstance 8-methylmenaquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_142110 chebi_ph7_3 GO:0047079 biolink:MolecularActivity deoxyuridine 1'-dioxygenase activity Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil. EC:1.14.11.10|RHEA:23316|MetaCyc:1.14.11.10-RXN|KEGG_REACTION:R02486 go-plus.json pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)|pyrimidine-deoxynucleoside 1'-dioxygenase activity http://purl.obolibrary.org/obo/GO_0047079 GO:0047081 biolink:MolecularActivity 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity Catalysis of the reaction: O2 + NADPH + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NADP+ + 2-(acetamidomethylene)succinate. MetaCyc:1.14.12.4-RXN|EC:1.14.13.242|RHEA:10864 go-plus.json methylhydroxypyridine carboxylate dioxygenase activity|methylhydroxypyridinecarboxylate oxidase activity|3-hydroxy-2-methylpyridine-5-carboxylate,NADPH:oxygen oxidoreductase (decyclizing)|3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity|2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity http://purl.obolibrary.org/obo/GO_0047081 GO:0047080 biolink:MolecularActivity deoxyuridine 2'-dioxygenase activity Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine. MetaCyc:1.14.11.3-RXN|EC:1.14.11.3|KEGG_REACTION:R01879|RHEA:21076 go-plus.json thymidine 2'-hydroxylase activity|thymidine 2-oxoglutarate dioxygenase activity|deoxyuridine 2'-hydroxylase activity|pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity|pyrimidine deoxyribonucleoside 2'-hydroxylase activity|thymidine dioxygenase activity|thymidine 2'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)|pyrimidine-deoxynucleoside 2'-dioxygenase activity http://purl.obolibrary.org/obo/GO_0047080 GO:0072039 biolink:BiologicalProcess regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. go-plus.json regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072039 GO:0072038 biolink:BiologicalProcess mesenchymal stem cell maintenance involved in nephron morphogenesis The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072038 GO:0072037 biolink:BiologicalProcess mesenchymal stem cell differentiation involved in nephron morphogenesis The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072037 GO:0072036 biolink:BiologicalProcess mesenchymal to epithelial transition involved in renal vesicle formation A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0072036 GO:0072035 biolink:BiologicalProcess pre-tubular aggregate formation The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney. go-plus.json mesenchymal cell condensation involved in renal vesicle formation|nephron epithelium formation http://purl.obolibrary.org/obo/GO_0072035 GO:0072023 biolink:BiologicalProcess thick ascending limb development The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. go-plus.json TAL development http://purl.obolibrary.org/obo/GO_0072023 GO:0047089 biolink:MolecularActivity dihydrochelirubine 12-monooxygenase activity Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+). EC:1.14.14.101|KEGG_REACTION:R04708|MetaCyc:1.14.13.57-RXN|RHEA:10156 go-plus.json dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)|dihydrochelirubine 12-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047089 GO:0047088 biolink:MolecularActivity dihydrosanguinarine 10-monooxygenase activity Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+). EC:1.14.14.100|RHEA:10528|KEGG_REACTION:R04702|MetaCyc:1.14.13.56-RXN go-plus.json dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)|dihydrosanguinarine 10-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047088 GO:0072022 biolink:BiologicalProcess descending thin limb development The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle. go-plus.json http://purl.obolibrary.org/obo/GO_0072022 GO:0072021 biolink:BiologicalProcess ascending thin limb development The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. go-plus.json http://purl.obolibrary.org/obo/GO_0072021 GO:0047087 biolink:MolecularActivity protopine 6-monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+). EC:1.14.14.98|RHEA:22644|KEGG_REACTION:R04699|MetaCyc:1.14.13.55-RXN go-plus.json protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)|protopine 6-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047087 GO:0047086 biolink:MolecularActivity ketosteroid monooxygenase activity Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate. EC:1.14.13.54|MetaCyc:1.14.13.54-RXN go-plus.json androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)|ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)|progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)|17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)|steroid-ketone monooxygenase activity http://purl.obolibrary.org/obo/GO_0047086 GO:0072020 biolink:BiologicalProcess proximal straight tubule development The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. go-plus.json S3 development http://purl.obolibrary.org/obo/GO_0072020 GO:0047085 biolink:MolecularActivity hydroxyphenylacetonitrile 2-monooxygenase activity Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+). KEGG_REACTION:R02708|RHEA:23740|MetaCyc:1.14.13.42-RXN go-plus.json 4-hydroxyphenylacetonitrile monooxygenase activity|4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)|4-hydroxyphenylacetonitrile hydroxylase activity http://purl.obolibrary.org/obo/GO_0047085 GO:0047084 biolink:MolecularActivity methyltetrahydroprotoberberine 14-monooxygenase activity Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine. EC:1.14.14.97|MetaCyc:1.14.13.37-RXN|RHEA:23684 go-plus.json (S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)|methyltetrahydroprotoberberine 14-hydroxylase activity|(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity|(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047084 CHEBI:8075 biolink:ChemicalSubstance phenoxyacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_8075 GO:0047083 biolink:MolecularActivity 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate. RHEA:16265|EC:1.14.14.96|MetaCyc:1.14.13.36-RXN go-plus.json coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity|trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)|5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047083 GO:0047082 biolink:MolecularActivity 3,9-dihydroxypterocarpan 6a-monooxygenase activity Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol. RHEA:15321|MetaCyc:RXN-4505|EC:1.14.14.93|KEGG_REACTION:R03452 go-plus.json 3,9-dihydroxypterocarpan 6a-hydroxylase activity|3,9-dihydroxypterocarpan 6alpha-monooxygenase|(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating) http://purl.obolibrary.org/obo/GO_0047082 CHEBI:132797 biolink:ChemicalSubstance 8-oxoresolvin D1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132797 CHEBI:142106 biolink:ChemicalSubstance 5,6-dihydrouridine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142106 chebi_ph7_3 GO:0047092 biolink:MolecularActivity 27-hydroxycholesterol 7-alpha-monooxygenase activity Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol. RHEA:24308|MetaCyc:1.14.13.60-RXN|EC:1.14.14.29 go-plus.json 27-hydroxycholesterol 7alpha-hydroxylase activity|27-hydroxycholesterol 7-alpha-hydroxylase activity|27-hydroxycholesterol 7a-hydroxylase activity|27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|27-hydroxycholesterol 7alpha-monooxygenase activity http://purl.obolibrary.org/obo/GO_0047092 GO:0047091 biolink:MolecularActivity L-lysine 6-monooxygenase (NADPH) activity Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+). KEGG_REACTION:R00448|MetaCyc:1.14.13.59-RXN|RHEA:23228|EC:1.14.13.59 go-plus.json L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)|lysine N(6)-hydroxylase activity|L-lysine 6-monooxygenase activity|lysine N6-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047091 GO:0047090 biolink:MolecularActivity benzoyl-CoA 3-monooxygenase activity Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+). KEGG_REACTION:R02449|MetaCyc:1.14.13.58-RXN|RHEA:23216|EC:1.14.13.58 go-plus.json benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)|benzoyl-CoA 3-hydroxylase activity http://purl.obolibrary.org/obo/GO_0047090 GO:0072029 biolink:BiologicalProcess long nephron development The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla. go-plus.json juxtamedullary nephron development http://purl.obolibrary.org/obo/GO_0072029 GO:0072028 biolink:BiologicalProcess nephron morphogenesis The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072028 GO:0072027 biolink:BiologicalProcess connecting tubule development The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct. go-plus.json connecting duct development http://purl.obolibrary.org/obo/GO_0072027 GO:0072026 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072026 GO:0072025 biolink:BiologicalProcess distal convoluted tubule development The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. go-plus.json http://purl.obolibrary.org/obo/GO_0072025 GO:0072024 biolink:BiologicalProcess macula densa development The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072024 CHEBI:74589 biolink:ChemicalSubstance Ser-tRNA(Sec) polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74589 chebi_ph7_3 GO:0106034 biolink:BiologicalProcess protein maturation by [2Fe-2S] cluster transfer The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0106034 GO:0106033 biolink:CellularComponent spine synapse A type of synapse occurring between an axon and a dendritic spine. go-plus.json dendritic spine synapse http://purl.obolibrary.org/obo/GO_0106033 CHEBI:74588 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z,22Z,25Z)-3-oxooctacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74588 GO:0106032 biolink:MolecularActivity snRNA pseudouridine synthase activity Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. go-plus.json http://purl.obolibrary.org/obo/GO_0106032 GO:0106038 biolink:BiologicalProcess obsolete vesicle assembly OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050). go-plus.json vesicle biosynthesis|vesicle formation http://purl.obolibrary.org/obo/GO_0106038 GO:0106037 biolink:CellularComponent apicomedial cortex The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell. go-plus.json medioapical cortex http://purl.obolibrary.org/obo/GO_0106037 CHEBI:25614 biolink:ChemicalSubstance nylons go-plus.json http://purl.obolibrary.org/obo/CHEBI_25614 GO:0106036 biolink:BiologicalProcess assembly of apicomedial cortex actomyosin A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin. go-plus.json http://purl.obolibrary.org/obo/GO_0106036 CHEBI:25613 biolink:ChemicalSubstance nucleotidyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_25613 GO:0106035 biolink:BiologicalProcess protein maturation by [4Fe-4S] cluster transfer The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0106035 GO:0106039 biolink:BiologicalProcess obsolete vesicle fusion involved in vesicle assembly OBSOLETE. A process carried out at the cellular level, which is the final step in vesicle assembly. Vesicle fusion occurs when a newly assembled vesicle closes up, following vesicle vesicle scission (GO:0099050). go-plus.json http://purl.obolibrary.org/obo/GO_0106039 CL:0002385 biolink:Cell blastoconidium An oblong or round asexual spore formed from conidial chains. go-plus.json blastospore http://purl.obolibrary.org/obo/CL_0002385 CL:0002387 biolink:Cell arthroconidium Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. go-plus.json arthrospore http://purl.obolibrary.org/obo/CL_0002387 CHEBI:74581 biolink:ChemicalSubstance gamma-linolenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74581 chebi_ph7_3 CHEBI:74583 biolink:ChemicalSubstance 1-icosanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74583 chebi_ph7_3 CHEBI:74582 biolink:ChemicalSubstance 1-(gamma-linolenoyl)-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74582 chebi_ph7_3 GO:0106041 biolink:BiologicalProcess positive regulation of GABA-A receptor activity Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0106041 CHEBI:74585 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74585 GO:0106040 biolink:BiologicalProcess regulation of GABA-A receptor activity Any process that modulates the frequency, rate or extent of GABA-A receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0106040 CHEBI:74584 biolink:ChemicalSubstance 1-icosanoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74584 chebi_ph7_3 CHEBI:74587 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74587 CHEBI:74586 biolink:ChemicalSubstance 1-myristoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74586 chebi_ph7_3 GO:0106045 biolink:BiologicalProcess guanine deglycation, methylglyoxal removal The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0106045 CHEBI:25622 biolink:ChemicalSubstance orthoquinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_25622 GO:0106044 biolink:BiologicalProcess guanine deglycation The removal of a sugar or dicarbonyl from a glycated guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0106044 GO:0106042 biolink:BiologicalProcess negative regulation of GABA-A receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0106042 CHEBI:25626 biolink:ChemicalSubstance octadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25626 chebi_ph7_3 GO:0106049 biolink:BiologicalProcess regulation of cellular response to osmotic stress Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress. go-plus.json http://purl.obolibrary.org/obo/GO_0106049 GO:0106048 biolink:BiologicalProcess spermidine deacetylation The modification of acetylspermadine by the removal of acetyl groups. go-plus.json N8-acetylspermidine deacetylation http://purl.obolibrary.org/obo/GO_0106048 GO:0106047 biolink:BiologicalProcess polyamine deacetylation The modification of acetylpolyamine by the removal of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0106047 GO:0106046 biolink:BiologicalProcess guanine deglycation, glyoxal removal The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0106046 CL:0002397 biolink:Cell CD14-positive, CD16-positive monocyte A CD14-positive monocyte that is also CD16-positive and CCR2-negative. go-plus.json CD16+ monocyte http://purl.obolibrary.org/obo/CL_0002397 CL:0002396 biolink:Cell CD14-low, CD16-positive monocyte A patrolling monocyte that is CD14-low and CD16-positive. go-plus.json non-classical monocyte, human http://purl.obolibrary.org/obo/CL_0002396 CL:0002398 biolink:Cell Gr1-positive, CD43-positive monocyte An intermediate monocyte that is Gr1-positive, CD43-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002398 CHEBI:74590 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74590 CHEBI:74592 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z,24Z,27Z)-3-oxotriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74592 CHEBI:25629 biolink:ChemicalSubstance octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25629 chebi_ph7_3 CHEBI:25627 biolink:ChemicalSubstance octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25627 CHEBI:74593 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74593 CL:0002393 biolink:Cell intermediate monocyte A monocyte that has characteristics of both patrolling and inflammatory monocytes. go-plus.json http://purl.obolibrary.org/obo/CL_0002393 CHEBI:74596 biolink:ChemicalSubstance Ins-1-P-Cer-C(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74596 chebi_ph7_3 CHEBI:74595 biolink:ChemicalSubstance (14Z,17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontahexaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74595 GO:0106050 biolink:MolecularActivity tRNA 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0106050 CL:0002395 biolink:Cell Gr1-high classical monocyte A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002395 CHEBI:74597 biolink:ChemicalSubstance Ins-1-P-Cer-C go-plus.json http://purl.obolibrary.org/obo/CHEBI_74597 GO:0106056 biolink:BiologicalProcess regulation of calcineurin-mediated signaling Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0106056 GO:0106055 biolink:CellularComponent mannosyl-oligosaccharide 1,2-alpha-mannosidase complex A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide. go-plus.json http://purl.obolibrary.org/obo/GO_0106055 GO:0106054 biolink:MolecularActivity tRNA U34 thiol-transferase activity Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+. go-plus.json tRNA-specific 2-thiouridylase|tRNA U34 2-thiouridylase http://purl.obolibrary.org/obo/GO_0106054 GO:0106059 biolink:MolecularActivity tRNA (cytidine 56-2'-O)-methyltransferase Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0106059 GO:0106058 biolink:BiologicalProcess positive regulation of calcineurin-mediated signaling Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0106058 GO:0106057 biolink:BiologicalProcess negative regulation of calcineurin-mediated signaling Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling. go-plus.json http://purl.obolibrary.org/obo/GO_0106057 CL:0002363 biolink:Cell keratocyte A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate. go-plus.json corneal keratocyte|corneal fibroblast http://purl.obolibrary.org/obo/CL_0002363 CL:0002368 biolink:Cell respiratory epithelial cell An endo-epithelial cell of the respiratory tract. go-plus.json airway epithelial cell http://purl.obolibrary.org/obo/CL_0002368 CL:0002367 biolink:Cell trabecular meshwork cell A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure. go-plus.json trabeculocyte http://purl.obolibrary.org/obo/CL_0002367 CL:0002369 biolink:Cell fungal spore A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. go-plus.json http://purl.obolibrary.org/obo/CL_0002369 GO:0106063 biolink:MolecularActivity G protein-coupled folate receptor activity Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. go-plus.json G-protein coupled folate receptor activity|G-protein coupled folic acid receptor activity http://purl.obolibrary.org/obo/GO_0106063 GO:0106062 biolink:BiologicalProcess positive regulation of exit from meiosis Any process that activates or increases the frequency, rate or extent of exit from meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0106062 GO:0106061 biolink:BiologicalProcess negative regulation of exit from meiosis Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0106061 CL:0002361 biolink:Cell primitive erythroid progenitor A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41. go-plus.json EryP-CFC|inner blood island hemangioblast http://purl.obolibrary.org/obo/CL_0002361 GO:0106060 biolink:BiologicalProcess regulation of exit from meiosis Any process that modulates the frequency, rate or extent of exit from mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0106060 GO:0106064 biolink:BiologicalProcess regulation of cobalamin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. go-plus.json http://purl.obolibrary.org/obo/GO_0106064 CHEBI:25604 biolink:ChemicalSubstance nucleotide-(amino alcohol)s go-plus.json http://purl.obolibrary.org/obo/CHEBI_25604 GO:0106069 biolink:CellularComponent synapsis initiation complex A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. go-plus.json http://purl.obolibrary.org/obo/GO_0106069 UBERON:0012490 biolink:AnatomicalEntity muscle layer of anal canal A muscular coat that is part of a anal canal. go-plus.json muscular coat of anal canal|anal muscularis propria|muscularis propria of anal canal|muscular layer of anal canal|muscularis externa of anal canal|anal canal muscularis propria http://purl.obolibrary.org/obo/UBERON_0012490 GO:0106068 biolink:CellularComponent SUMO ligase complex A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex. go-plus.json SUMO-protein ligase complex|SUMO transferase complex|Sumoylation complex http://purl.obolibrary.org/obo/GO_0106068 UBERON:0012499 biolink:AnatomicalEntity serosa of uterine tube A serous membrane that is part of a fallopian tube. go-plus.json serosa of oviduct|uterine tubal serosa|serosa of fallopian tube|tunica serosa (tuba uterina)|uterine tube serosa|tunica serosa tubae uterinae|serous coat of uterine tube http://purl.obolibrary.org/obo/UBERON_0012499 CL:0002375 biolink:Cell Schwann cell precursor A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19. go-plus.json Schwann cell precursor cell http://purl.obolibrary.org/obo/CL_0002375 CL:0002374 biolink:Cell ear hair cell A hair cell of the ear that contains the organs of balance and hearing. go-plus.json ear receptor cell http://purl.obolibrary.org/obo/CL_0002374 CL:0002377 biolink:Cell immature Schwann cell A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. go-plus.json Schwann cell http://purl.obolibrary.org/obo/CL_0002377 GO:0106070 biolink:BiologicalProcess regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. go-plus.json regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106070 CHEBI:25608 biolink:ChemicalSubstance nucleoside phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25608 CHEBI:25605 biolink:ChemicalSubstance nucleoside antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_25605 GO:0106074 biolink:BiologicalProcess aminoacyl-tRNA metabolism involved in translational fidelity Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation. go-plus.json aminoacyl-tRNA correction|aminoacyl-tRNA editin|aminoacyl-tRNA proofreading http://purl.obolibrary.org/obo/GO_0106074 CL:0002371 biolink:Cell somatic cell A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). go-plus.json http://purl.obolibrary.org/obo/CL_0002371 GO:0106073 biolink:MolecularActivity dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. RHEA:29543|EC:2.4.1.256 go-plus.json http://purl.obolibrary.org/obo/GO_0106073 CL:0002370 biolink:Cell respiratory goblet cell A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. go-plus.json respiratory mucosa goblet cells http://purl.obolibrary.org/obo/CL_0002370 GO:0106072 biolink:BiologicalProcess negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. go-plus.json negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106072 GO:0106071 biolink:BiologicalProcess positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. go-plus.json positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0106071 CL:0002372 biolink:Cell myotube A transversely striated, synctial muscle cell, formed by the fusion of myoblasts. go-plus.json myotubule|single cell sarcomere http://purl.obolibrary.org/obo/CL_0002372 CHEBI:25609 biolink:ChemicalSubstance nucleotide-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_25609 NCBITaxon:480118 biolink:OrganismalEntity Eremoneura go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_480118 NCBITaxon:480117 biolink:OrganismalEntity Cyclorrhapha go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_480117 CL:0002341 biolink:Cell basal cell of prostate epithelium An undifferentiated cell of the prostate epithelium that lacks secretory activity. go-plus.json http://purl.obolibrary.org/obo/CL_0002341 CL:1000376 biolink:Cell Purkinje myocyte of interventricular septum A Purkinje myocyte that is part of the interventricular septum. go-plus.json http://purl.obolibrary.org/obo/CL_1000376 CL:0002344 biolink:Cell CD56-negative, CD161-positive immature natural killer cell, human A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. go-plus.json p-NK http://purl.obolibrary.org/obo/CL_0002344 CL:0002346 biolink:Cell Dx5-negative, NK1.1-positive immature natural killer cell, mouse An immature natural killer cell that is NK1.1-positive and DX-5 negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002346 GO:0106001 biolink:BiologicalProcess intestinal hexose absorption Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0106001 GO:0106005 biolink:BiologicalProcess RNA 5'-cap (guanine-N7)-methylation The process whereby a guanine in 5-cap is methylated at the N7 position of guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0106005 GO:0106004 biolink:BiologicalProcess tRNA (guanine-N7)-methylation The process whereby a guanine in a tRNA is methylated at the N7 position of guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0106004 GO:0106003 biolink:CellularComponent amyloid-beta complex Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine loss leading to decreased synapse density, inhibits long-term potentiation (LTP) and enhances long-term depression (LTD). Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease. go-plus.json amyloid beta heterooligomer|heterotrimer of amyloid beta protein|amyloid beta homooligomer|amyloid beta trimer|Abeta-derived diffusible ligand complex|homotrimer of amyloid beta protein|beta amyloid complex|heterooligomer of amyloid beta protein|amyloid beta oligomer|homooligomer of amyloid beta protein|homodimer of amyloid beta protein|betaA complex|Abeta complex|ADDL complex|heterodimer of amyloid beta protein|amyloid beta dimer|amyloid-beta protein 42 complex|beta-amyloid complex|amyloid-beta protein 40 complex|amyloid-beta protein 40/42 complex|amyloid beta heterotrimer|amyloid beta homotrimer|amyloid beta homodimer|amyloid beta complex|amyloid beta heterodimer http://purl.obolibrary.org/obo/GO_0106003 GO:0106002 biolink:CellularComponent mCRD-mediated mRNA stability complex A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP. go-plus.json major coding region instability determinant-poly(A)-bridging complex|mCRD-poly(A)-bridging complex|major coding-region determinant of instability - poly(A) tail-bridging complex|major coding region determinant of instability-mediated mRNA stability complex|major coding region instability determinant-mediated mRNA stability complex http://purl.obolibrary.org/obo/GO_0106002 GO:0106009 biolink:MolecularActivity (4S)-4-hydroxy-2-oxoglutarate aldolase activity Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. RHEA:35639|EC:4.1.3.42 go-plus.json http://purl.obolibrary.org/obo/GO_0106009 GO:0023070 biolink:BiologicalProcess obsolete signal transmission via air OBSOLETE. The process in which a signal is conveyed via the air. go-plus.json signal transmission via air http://purl.obolibrary.org/obo/GO_0023070 GO:0106008 biolink:MolecularActivity 2-oxoglutaramate amidase activity Catalysis of the reaction: 2-oxoglutaramate + H(2)O = 2-oxoglutarate + NH(3). RHEA:32963|EC:3.5.1.111 go-plus.json http://purl.obolibrary.org/obo/GO_0106008 GO:0106007 biolink:BiologicalProcess microtubule anchoring at cell cortex of cell tip Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0106007 GO:0106006 biolink:MolecularActivity cytoskeletal protein-membrane anchor activity The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location. go-plus.json cytoskeletal protein-membrane adaptor activity|F-BAR domain adaptor|microtubule cortical anchor activity|cytoskeletal protein membrane adaptor|BAR domain adaptor|membrane-cytoskeletal protein tether activity|cytoskeletal protein membrane tether activity|membrane-cytoskeletal protein anchor activity|cytoskeletal protein membrane anchor activity http://purl.obolibrary.org/obo/GO_0106006 CL:0002353 biolink:Cell fetal liver hematopoietic progenitor cell A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002353 CL:0002352 biolink:Cell gestational hematopoietic stem cell A hematopoietic stem cell that exists during embryogenesis. go-plus.json http://purl.obolibrary.org/obo/CL_0002352 CL:0002355 biolink:Cell primitive red blood cell A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation. go-plus.json primitive erythroblast|primitive erythrocyte|primitive erythroid cell http://purl.obolibrary.org/obo/CL_0002355 CL:0002354 biolink:Cell yolk sac hematopoietic stem cell A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. go-plus.json hemangioblast precursor http://purl.obolibrary.org/obo/CL_0002354 CL:0002357 biolink:Cell fetal derived definitive erythrocyte A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins. go-plus.json macrocyte http://purl.obolibrary.org/obo/CL_0002357 CL:0002356 biolink:Cell primitive reticulocyte A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains. go-plus.json megalocyte http://purl.obolibrary.org/obo/CL_0002356 CL:0002359 biolink:Cell placental hematopoietic stem cell A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. go-plus.json http://purl.obolibrary.org/obo/CL_0002359 CL:0002358 biolink:Cell pyrenocyte Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte. go-plus.json http://purl.obolibrary.org/obo/CL_0002358 CL:0002351 biolink:Cell progenitor cell of endocrine pancreas A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. go-plus.json pancreatic endocrine progenitor|pancreatic islet progenitor cell http://purl.obolibrary.org/obo/CL_0002351 CL:0002350 biolink:Cell endocardial cell An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. go-plus.json endocardial endothelial cell|endothelial cell of endocardium http://purl.obolibrary.org/obo/CL_0002350 GO:0023067 biolink:BiologicalProcess obsolete signal transmission via lymphatic system OBSOLETE. The process in which a signal is conveyed via the lymphatic system. go-plus.json signal transmission via lymphatic system http://purl.obolibrary.org/obo/GO_0023067 GO:0106012 biolink:BiologicalProcess positive regulation of protein localization to medial cortex Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0106012 GO:0023066 biolink:BiologicalProcess obsolete signal transmission via vascular system OBSOLETE. The process in which a signal is conveyed via the vascular system. go-plus.json signal transmission via vascular system http://purl.obolibrary.org/obo/GO_0023066 GO:0106011 biolink:BiologicalProcess regulation of protein localization to medial cortex Any process that regulates the localization of a protein to the medial cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0106011 GO:0023069 biolink:BiologicalProcess obsolete signal transmission via xylem OBSOLETE. The process in which a signal is conveyed via the xylem. go-plus.json signal transmission via xylem http://purl.obolibrary.org/obo/GO_0023069 GO:0023068 biolink:BiologicalProcess obsolete signal transmission via phloem OBSOLETE. The process in which a signal is conveyed via the phloem. go-plus.json signal transmission via phloem http://purl.obolibrary.org/obo/GO_0023068 GO:0106016 biolink:BiologicalProcess positive regulation of inflammatory response to wounding Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0106016 GO:0106015 biolink:BiologicalProcess negative regulation of inflammatory response to wounding Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0106015 GO:0106014 biolink:BiologicalProcess regulation of inflammatory response to wounding Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. go-plus.json http://purl.obolibrary.org/obo/GO_0106014 GO:0106013 biolink:BiologicalProcess negative regulation of protein localization to cell cortex of cell tip Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip. go-plus.json http://purl.obolibrary.org/obo/GO_0106013 CL:0002328 biolink:Cell bronchial epithelial cell An epithelial cell of the bronchus. go-plus.json http://purl.obolibrary.org/obo/CL_0002328 GO:0106019 biolink:MolecularActivity phosphatidylinositol-4,5-bisphosphate phosphatase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106019 CL:0002327 biolink:Cell mammary gland epithelial cell An epithelial cell of the mammary gland. go-plus.json mammary epithelial cell|breast epithelial cell http://purl.obolibrary.org/obo/CL_0002327 GO:0023061 biolink:BiologicalProcess signal release The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. go-plus.json signal secretion http://purl.obolibrary.org/obo/GO_0023061 GO:0106018 biolink:MolecularActivity phosphatidylinositol-3,5-bisphosphate phosphatase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106018 GO:0023060 biolink:BiologicalProcess obsolete signal transmission OBSOLETE. The process in which a signal is released and/or conveyed from one location to another. go-plus.json signal transmission http://purl.obolibrary.org/obo/GO_0023060 GO:0106017 biolink:MolecularActivity phosphatidylinositol-3,4-bisphosphate phosphatase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106017 CL:0002329 biolink:Cell basal epithelial cell of tracheobronchial tree An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. go-plus.json http://purl.obolibrary.org/obo/CL_0002329 GO:0023062 biolink:BiologicalProcess obsolete signal transmission via transcytosis OBSOLETE. The process in which a signal is conveyed via transcytosis. Transcytosis is the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. go-plus.json signal transmission via transcytosis http://purl.obolibrary.org/obo/GO_0023062 GO:0023065 biolink:BiologicalProcess obsolete signal transmission via blood OBSOLETE. The process in which a signal is conveyed via blood. go-plus.json signal transmission via blood http://purl.obolibrary.org/obo/GO_0023065 CHEBI:142198 biolink:ChemicalSubstance purine 2'-deoxyribonucleoside 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142198 chebi_ph7_3 CL:0002320 biolink:Cell connective tissue cell A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. go-plus.json http://purl.obolibrary.org/obo/CL_0002320 CL:0002322 biolink:Cell embryonic stem cell A stem cell of embryonic origin. go-plus.json ESC http://purl.obolibrary.org/obo/CL_0002322 CL:0002321 biolink:Cell embryonic cell (metazoa) A cell of the embryo. go-plus.json http://purl.obolibrary.org/obo/CL_0002321 CL:0002323 biolink:Cell amniocyte A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. go-plus.json http://purl.obolibrary.org/obo/CL_0002323 CL:0002325 biolink:Cell mammary alveolar cell The milk-producing cell of the alveolar unit that emerges during pregnancy. go-plus.json epithelial cell of lactiferous gland|luminal cell of alveolus of lactiferous gland http://purl.obolibrary.org/obo/CL_0002325 CL:1000391 biolink:Cell melanocyte of eyelid A melanocyte that is part of the eyelid. go-plus.json sebaceous gland of wolff|eyelid melanocyte http://purl.obolibrary.org/obo/CL_1000391 GO:0023056 biolink:BiologicalProcess positive regulation of signaling Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. go-plus.json positive regulation of signalling process|positive regulation of signaling process http://purl.obolibrary.org/obo/GO_0023056 GO:0047001 biolink:MolecularActivity 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate. MetaCyc:1.1.1.127-RXN|RHEA:24232|EC:1.1.1.127 go-plus.json 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity|2-keto-3-deoxygluconate 5-dehydrogenase activity|2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity|2-keto-3-deoxygluconate dehydrogenase activity|2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047001 GO:0106023 biolink:BiologicalProcess regulation of pupariation Any process that modulates the onset of pupariation. go-plus.json http://purl.obolibrary.org/obo/GO_0106023 GO:0106022 biolink:BiologicalProcess positive regulation of vesicle docking Any process that activates or increases the frequency, rate or extent of vesicle docking. go-plus.json positive regulation of vesicle to membrane docking http://purl.obolibrary.org/obo/GO_0106022 GO:0023055 biolink:BiologicalProcess obsolete signal initiation by peptide hormone OBSOLETE. The process in which a signal is initiated by a peptide hormone. go-plus.json signal initiation by peptide hormone http://purl.obolibrary.org/obo/GO_0023055 GO:0047000 biolink:MolecularActivity 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH. RHEA:15109|KEGG_REACTION:R01543|MetaCyc:1.1.1.126-RXN|EC:1.1.1.126 go-plus.json 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity|2-keto-3-deoxy-D-gluconate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047000 GO:0023058 biolink:BiologicalProcess adaptation of signaling pathway The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. go-plus.json adaptation of signalling pathway http://purl.obolibrary.org/obo/GO_0023058 GO:0106021 biolink:BiologicalProcess negative regulation of vesicle docking Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking. go-plus.json negative regulation of vesicle to membrane docking http://purl.obolibrary.org/obo/GO_0106021 GO:0106020 biolink:BiologicalProcess regulation of vesicle docking Any process that modulates the frequency, rate or extent of vesicle docking. go-plus.json regulation of vesicle to membrane docking http://purl.obolibrary.org/obo/GO_0106020 GO:0023057 biolink:BiologicalProcess negative regulation of signaling Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. go-plus.json negative regulation of signalling process|negative regulation of signaling process http://purl.obolibrary.org/obo/GO_0023057 GO:0106027 biolink:BiologicalProcess neuron projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0106027 GO:0023059 biolink:BiologicalProcess positive adaptation of signaling pathway The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. go-plus.json positive adaptation of signalling pathway http://purl.obolibrary.org/obo/GO_0023059 GO:0106026 biolink:MolecularActivity Gly-tRNA(Ala) hydrolase activity Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala). go-plus.json http://purl.obolibrary.org/obo/GO_0106026 GO:0106025 biolink:BiologicalProcess positive regulation of pupariation Any process that activates or increases the frequency, rate or extent of onset of pupariation. go-plus.json http://purl.obolibrary.org/obo/GO_0106025 GO:0106024 biolink:BiologicalProcess negative regulation of pupariation Any process that stops, prevents or reduces the rate of onset of pupariation. go-plus.json http://purl.obolibrary.org/obo/GO_0106024 GO:0047009 biolink:MolecularActivity 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione. RHEA:10356|MetaCyc:1.1.1.152-RXN|EC:1.1.1.152 go-plus.json 3alpha-hydroxy-5beta-steroid dehydrogenase activity|etiocholanolone 3alpha-dehydrogenase activity|3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity|etiocholanolone 3-alpha-dehydrogenase activity|3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047009 CL:0002339 biolink:Cell prostate stem cell A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. go-plus.json CD133-positive prostate epithelial cell http://purl.obolibrary.org/obo/CL_0002339 CL:0002338 biolink:Cell CD56-positive, CD161-positive immature natural killer cell, human A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive. go-plus.json p-NK http://purl.obolibrary.org/obo/CL_0002338 GO:0047008 biolink:MolecularActivity pregnan-21-ol dehydrogenase (NADP+) activity Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al. RHEA:23712|KEGG_REACTION:R03044|MetaCyc:1.1.1.151-RXN|EC:1.1.1.151 go-plus.json 21-hydroxysteroid:NADP+ 21-oxidoreductase activity|21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity|21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|21-hydroxysteroid dehydrogenase (NADP+) activity|21-hydroxy steroid dehydrogenase activity|NADP-21-hydroxysteroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047008 GO:0106029 biolink:MolecularActivity tRNA pseudouridine synthase activity Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. RHEA:22376|EC:5.4.99.28|EC:5.4.99.27|EC:5.4.99.26|EC:5.4.99.25|EC:5.4.99.45|EC:5.4.99.12|EC:5.4.99.44|EC:5.4.99.42|MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN go-plus.json tRNA pseudouridine(13) synthase|tRNA pseudouridine(55) synthase|tRNA pseudouridine(65) synthase|tRNA pseudouridine(32) synthase|tRNA pseudouridine(38/39) synthase|transfer ribonucleate pseudouridine synthetase activity|tRNA-pseudouridine synthase activity|tRNA-uridine isomerase activity|transfer RNA pseudouridine synthetase activity|tRNA pseudouridylate synthase I activity|Mitochondrial tRNA pseudouridine(27/28) synthase|tRNA pseudouridine(38-40) synthase|tRNA-pseudouridine synthase I activity|tRNA pseudouridine(31) synthase|tRNA-uridine uracilmutase activity http://purl.obolibrary.org/obo/GO_0106029 GO:0023050 biolink:BiologicalProcess obsolete consequence of signal transmission OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state. go-plus.json consequence of signal transmission|signal termination http://purl.obolibrary.org/obo/GO_0023050 GO:0047007 biolink:MolecularActivity pregnan-21-ol dehydrogenase (NAD+) activity Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al. RHEA:11448|KEGG_REACTION:R03043|MetaCyc:1.1.1.150-RXN|EC:1.1.1.150 go-plus.json 21-hydroxysteroid dehydrogenase (NAD+) activity|21-hydroxysteroid:NAD+ 21-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047007 GO:0106028 biolink:BiologicalProcess neuron projection retraction The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. go-plus.json neuron projection disassembly http://purl.obolibrary.org/obo/GO_0106028 GO:0047006 biolink:MolecularActivity 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone. MetaCyc:1.1.1.149-RXN|EC:1.1.1.149 go-plus.json 20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity|20alpha-HSD|20alpha-hydroxysteroid dehydrogenase|20alpha-HSDH|20alpha-hydroxy steroid dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047006 GO:0047005 biolink:MolecularActivity 16-alpha-hydroxysteroid dehydrogenase activity Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid. MetaCyc:1.1.1.147-RXN|EC:1.1.1.147 go-plus.json 16alpha-hydroxy steroid dehydrogenase activity|16alpha-hydroxysteroid dehydrogenase activity|16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047005 GO:0023052 biolink:BiologicalProcess signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. go-plus.json single organism signaling|signalling|biological signaling|signaling process|signalling process http://purl.obolibrary.org/obo/GO_0023052 goslim_pombe|goslim_flybase_ribbon|goslim_mouse|goslim_yeast|goslim_agr GO:0023051 biolink:BiologicalProcess regulation of signaling Any process that modulates the frequency, rate or extent of a signaling process. go-plus.json regulation of signaling process|regulation of signalling process http://purl.obolibrary.org/obo/GO_0023051 GO:0047004 biolink:MolecularActivity UDP-N-acetylglucosamine 6-dehydrogenase activity Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate. KEGG_REACTION:R00421|RHEA:13325|MetaCyc:1.1.1.136-RXN|EC:1.1.1.136 go-plus.json UDPacetylglucosamine dehydrogenase activity|UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity|uridine diphosphoacetylglucosamine dehydrogenase activity|UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity|UDP-GLcNAc dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047004 GO:0047003 biolink:MolecularActivity dTDP-6-deoxy-L-talose 4-dehydrogenase activity Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH. RHEA:23648|KEGG_REACTION:R02776|MetaCyc:1.1.1.134-RXN|EC:1.1.1.134 go-plus.json dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)|dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity|TDP-6-deoxy-L-talose dehydrogenase activity|thymidine diphospho-6-deoxy-L-talose dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047003 GO:0023054 biolink:BiologicalProcess obsolete signal initiation by stretch effect OBSOLETE. The process in which a stretch signal causes activation of a receptor. go-plus.json signal initiation by stretch effect http://purl.obolibrary.org/obo/GO_0023054 GO:0047002 biolink:MolecularActivity L-arabinitol 2-dehydrogenase activity Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH. EC:1.1.1.13|RHEA:21356|KEGG_REACTION:R02441|MetaCyc:1.1.1.13-RXN go-plus.json L-arabinitol 2-dehydrogenase (ribulose forming) activity http://purl.obolibrary.org/obo/GO_0047002 GO:0023053 biolink:BiologicalProcess obsolete signal initiation by mechanical effect OBSOLETE. The process in which a mechanical signal causes activation of a receptor. go-plus.json signal initiation by mechanical effect http://purl.obolibrary.org/obo/GO_0023053 CL:0002333 biolink:Cell neural crest derived fat cell A fat cell derived from a neural crest cell. go-plus.json http://purl.obolibrary.org/obo/CL_0002333 CL:0002332 biolink:Cell ciliated cell of the bronchus A ciliated cell of the bronchus. go-plus.json http://purl.obolibrary.org/obo/CL_0002332 CL:0002335 biolink:Cell brown preadipocyte A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha). go-plus.json http://purl.obolibrary.org/obo/CL_0002335 CL:0002334 biolink:Cell preadipocyte An undifferentiated fibroblast that can be stimulated to form a fat cell. go-plus.json http://purl.obolibrary.org/obo/CL_0002334 GO:0106030 biolink:BiologicalProcess neuron projection fasciculation The collection of neuronal projections into a bundle of rods, known as a fascicle. go-plus.json http://purl.obolibrary.org/obo/GO_0106030 CHEBI:132809 biolink:ChemicalSubstance (8S)-hepoxilin A3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132809 CHEBI:49544 biolink:ChemicalSubstance chromium(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49544 chebi_ph7_3 CHEBI:50533 biolink:ChemicalSubstance protein denaturant go-plus.json http://purl.obolibrary.org/obo/CHEBI_50533 CHEBI:132808 biolink:ChemicalSubstance (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132808 CHEBI:74503 biolink:ChemicalSubstance Ins-1-P-Cer-A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74503 chebi_ph7_3 CHEBI:25576 biolink:ChemicalSubstance nonadienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25576 CHEBI:50532 biolink:ChemicalSubstance (S)-beta-alanopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50532 CHEBI:74502 biolink:ChemicalSubstance N(3)-methyluridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74502 chebi_ph7_3 CHEBI:50531 biolink:ChemicalSubstance (R)-beta-alanopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50531 CHEBI:25575 biolink:ChemicalSubstance nonadienedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25575 CHEBI:74505 biolink:ChemicalSubstance Ins-1-P-Cer-A go-plus.json http://purl.obolibrary.org/obo/CHEBI_74505 CHEBI:74504 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z)-3-oxodotriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74504 CHEBI:74506 biolink:ChemicalSubstance N(4)-methylcytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74506 chebi_ph7_3 CHEBI:25579 biolink:ChemicalSubstance nonanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25579 CHEBI:132801 biolink:ChemicalSubstance 18(S)-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_132801 CHEBI:132800 biolink:ChemicalSubstance 17-oxoresolvin D1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132800 CHEBI:74508 biolink:ChemicalSubstance 5-carboxymethylaminomethyluridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74508 chebi_ph7_3 CHEBI:132803 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132803 CHEBI:132802 biolink:ChemicalSubstance (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132802 NCBITaxon:3847 biolink:OrganismalEntity Glycine max go-plus.json soybean|soybeans|Phaseolus max http://purl.obolibrary.org/obo/NCBITaxon_3847 CHEBI:132805 biolink:ChemicalSubstance beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_132805 NCBITaxon:3846 biolink:OrganismalEntity Glycine go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3846 CHEBI:132804 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-galactosamine 4-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132804 CL:1000458 biolink:Cell melanocyte of skin A melanocyte that is part of the skin of body. go-plus.json skin melanocyte http://purl.obolibrary.org/obo/CL_1000458 CL:1000457 biolink:Cell mesothelial cell of visceral peritoneum A mesothelial cell that is part of the visceral peritoneum. go-plus.json http://purl.obolibrary.org/obo/CL_1000457 CHEBI:25572 biolink:ChemicalSubstance nocardicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25572 CL:1000456 biolink:Cell mesothelial cell of parietal peritoneum A mesothelial cell that is part of the parietal peritoneum. go-plus.json http://purl.obolibrary.org/obo/CL_1000456 CL:1000450 biolink:Cell epithelial cell of glomerular capsule An epithelial cell that is part of the glomerular capsule. go-plus.json epithelial cell of Bowman's capsule|Bowmans capsule epithelial cell http://purl.obolibrary.org/obo/CL_1000450 CHEBI:50523 biolink:ChemicalSubstance butenolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50523 CHEBI:74512 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74512 CHEBI:74511 biolink:ChemicalSubstance 5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74511 chebi_ph7_3 CHEBI:50521 biolink:ChemicalSubstance N-methylnicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50521 CHEBI:74513 biolink:ChemicalSubstance N(2),N(2)-dimethylguanosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74513 chebi_ph7_3 CHEBI:74515 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z)-3-oxotetratriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74515 CHEBI:49537 biolink:ChemicalSubstance c-di-GMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_49537 CHEBI:50526 biolink:ChemicalSubstance phenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50526 CHEBI:74518 biolink:ChemicalSubstance anti-obesity agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_74518 CHEBI:50525 biolink:ChemicalSubstance phenolate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_50525 CHEBI:50524 biolink:ChemicalSubstance catecholate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50524 CHEBI:74519 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74519 CHEBI:132814 biolink:ChemicalSubstance beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)-beta-D-Galp-(1->4)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_132814 chebi_ph7_3 CHEBI:50528 biolink:ChemicalSubstance FMNH(.) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50528 CL:1000449 biolink:Cell epithelial cell of nephron An epithelial cell that is part of the nephron. go-plus.json http://purl.obolibrary.org/obo/CL_1000449 CHEBI:25585 biolink:ChemicalSubstance nonmetal atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_25585 CL:1000448 biolink:Cell epithelial cell of sweat gland An epithelial cell that is part of the sweat gland. go-plus.json http://purl.obolibrary.org/obo/CL_1000448 CHEBI:132818 biolink:ChemicalSubstance apigenin 7-O-beta-L-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_132818 CL:1000443 biolink:Cell ciliary muscle cell A smooth muscle cell that is part of the ciliary body. go-plus.json smooth muscle cell of ciliary body http://purl.obolibrary.org/obo/CL_1000443 CHEBI:50511 biolink:ChemicalSubstance bipyridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_50511 CHEBI:74522 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z)-3-oxohexatriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74522 CHEBI:25555 biolink:ChemicalSubstance nitrogen atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_25555 CHEBI:50510 biolink:ChemicalSubstance potassium channel modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50510 CHEBI:74525 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74525 CHEBI:50516 biolink:ChemicalSubstance (24R)-24-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50516 chebi_ph7_3 CHEBI:50515 biolink:ChemicalSubstance 24-hydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50515 chebi_ph7_3 CHEBI:50514 biolink:ChemicalSubstance vasoconstrictor agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50514 CHEBI:74529 biolink:ChemicalSubstance antidote to paracetamol poisoning go-plus.json http://purl.obolibrary.org/obo/CHEBI_74529 CHEBI:25558 biolink:ChemicalSubstance organonitrogen heterocyclic antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_25558 CHEBI:50513 biolink:ChemicalSubstance mydriatic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50513 CHEBI:50519 biolink:ChemicalSubstance sulfoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50519 CHEBI:50517 biolink:ChemicalSubstance 7alpha,24-dihydroxycholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50517 chebi_ph7_3 UBERON:0036553 biolink:AnatomicalEntity wall of synovial tendon sheath go-plus.json http://purl.obolibrary.org/obo/UBERON_0036553 CHEBI:25550 biolink:ChemicalSubstance nitroaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_25550 CL:1000479 biolink:Cell Purkinje myocyte of atrioventricular node A Purkinje myocyte that is part of the atrioventricular node. go-plus.json http://purl.obolibrary.org/obo/CL_1000479 CHEBI:25567 biolink:ChemicalSubstance nitrous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25567 chebi_ph7_3 CHEBI:25566 biolink:ChemicalSubstance nitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_25566 CHEBI:74535 biolink:ChemicalSubstance N-[(15Z)-tetracosenoyl]sphing-4-enine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74535 chebi_ph7_3 CHEBI:50505 biolink:ChemicalSubstance sweetening agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50505 CHEBI:50504 biolink:ChemicalSubstance osmotic diuretic go-plus.json http://purl.obolibrary.org/obo/CHEBI_50504 CHEBI:50503 biolink:ChemicalSubstance laxative go-plus.json http://purl.obolibrary.org/obo/CHEBI_50503 CHEBI:50502 biolink:ChemicalSubstance EC 2.5.1.15 (dihydropteroate synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50502 CHEBI:50509 biolink:ChemicalSubstance potassium channel blocker go-plus.json http://purl.obolibrary.org/obo/CHEBI_50509 CHEBI:25562 biolink:ChemicalSubstance nitrophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25562 CHEBI:25560 biolink:ChemicalSubstance nitroglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25560 CL:1000465 biolink:Cell chromaffin cell of ovary A chromaffin cell that is part of the ovary. go-plus.json http://purl.obolibrary.org/obo/CL_1000465 CHEBI:74530 biolink:ChemicalSubstance antidote to curare poisoning go-plus.json http://purl.obolibrary.org/obo/CHEBI_74530 CHEBI:25534 biolink:ChemicalSubstance nicotinic acid nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25534 CHEBI:74544 biolink:ChemicalSubstance 1-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74544 chebi_ph7_3 CHEBI:25533 biolink:ChemicalSubstance N-glycosylnicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25533 CHEBI:74547 biolink:ChemicalSubstance 1-linoleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74547 chebi_ph7_3 CHEBI:74546 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74546 chebi_ph7_3 CHEBI:74549 biolink:ChemicalSubstance 1-linolenoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74549 chebi_ph7_3 CHEBI:74548 biolink:ChemicalSubstance 1-linoleoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74548 chebi_ph7_3 CL:1000415 biolink:Cell epithelial cell of gall bladder An epithelial cell that is part of the gallbladder. go-plus.json http://purl.obolibrary.org/obo/CL_1000415 CL:1000413 biolink:Cell endothelial cell of artery A blood vessel endothelial cell that is part of an arterial endothelium. go-plus.json arterial endothelial cell http://purl.obolibrary.org/obo/CL_1000413 CL:0002188 biolink:Cell glomerular endothelial cell An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate. go-plus.json http://purl.obolibrary.org/obo/CL_0002188 CL:1000410 biolink:Cell myocyte of atrioventricular node A muscle cell that is part of the atrioventricular node. go-plus.json AV nodal myocyte|atrioventricular node cell|AV node cardiac muscle cell|AV node cell|atrioventricular node myocyte http://purl.obolibrary.org/obo/CL_1000410 CL:0002187 biolink:Cell basal cell of epidermis A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane. go-plus.json http://purl.obolibrary.org/obo/CL_0002187 CHEBI:74543 biolink:ChemicalSubstance 8-methyladenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74543 chebi_ph7_3 CHEBI:74556 biolink:ChemicalSubstance 1-heptadecanoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74556 chebi_ph7_3 CHEBI:74558 biolink:ChemicalSubstance 1-oleoyl-2-heptadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74558 chebi_ph7_3 CHEBI:25548 biolink:ChemicalSubstance nitrilotriacetate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_25548 chebi_ph7_3 CL:1000409 biolink:Cell myocyte of sinoatrial node A muscle cell that is part of the sinoatrial node. go-plus.json SA nodal myocyte|myocyte of sinoatrial node|SA node cardiac muscle cell|sinoatrial node myocyte|sinuatrial node myocyte|sinoatrial node cell http://purl.obolibrary.org/obo/CL_1000409 CHEBI:25540 biolink:ChemicalSubstance neonicotinoid insectide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25540 CL:0002191 biolink:Cell granulocytopoietic cell A cell involved in the formation of a granulocyte. go-plus.json http://purl.obolibrary.org/obo/CL_0002191 CL:0002193 biolink:Cell myelocyte A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. go-plus.json http://purl.obolibrary.org/obo/CL_0002193 CHEBI:74550 biolink:ChemicalSubstance 1-linolenoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74550 chebi_ph7_3 CL:0002192 biolink:Cell metamyelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. go-plus.json http://purl.obolibrary.org/obo/CL_0002192 CL:0002195 biolink:Cell hepatic stem cell A stem cell that can give rise to the cells of the liver. go-plus.json http://purl.obolibrary.org/obo/CL_0002195 CHEBI:74552 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74552 chebi_ph7_3 CHEBI:74551 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74551 chebi_ph7_3 CL:0002194 biolink:Cell monopoietic cell A cell involved in the formation of a monocyte (monopoiesis). go-plus.json http://purl.obolibrary.org/obo/CL_0002194 CHEBI:74554 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74554 chebi_ph7_3 CHEBI:25512 biolink:ChemicalSubstance neurotransmitter go-plus.json http://purl.obolibrary.org/obo/CHEBI_25512 CHEBI:25516 biolink:ChemicalSubstance nickel cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25516 chebi_ph7_3 CHEBI:25513 biolink:ChemicalSubstance neutral glycosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25513 CL:0002167 biolink:Cell olfactory epithelial cell A specialized cell involved in sensory perception of smell. go-plus.json http://purl.obolibrary.org/obo/CL_0002167 OIO:shorthand biolink:OntologyClass shorthand go-plus.json http://www.geneontology.org/formats/oboInOwl#shorthand CHEBI:25519 biolink:ChemicalSubstance nickel tetrapyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_25519 CHEBI:74560 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74560 chebi_ph7_3 CHEBI:74563 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74563 chebi_ph7_3 CHEBI:74565 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74565 chebi_ph7_3 CHEBI:25523 biolink:ChemicalSubstance NADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_25523 CHEBI:74578 biolink:ChemicalSubstance 1-oleoyl-2-pentadecanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74578 chebi_ph7_3 CHEBI:74577 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74577 CHEBI:74579 biolink:ChemicalSubstance 1-oleoyl-2-myristoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74579 chebi_ph7_3 NCBITaxon:3877 biolink:OrganismalEntity Medicago go-plus.json medics http://purl.obolibrary.org/obo/NCBITaxon_3877 CHEBI:25520 biolink:ChemicalSubstance nicotianamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25520 CHEBI:25527 biolink:ChemicalSubstance nicotinamide nucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25527 CHEBI:25526 biolink:ChemicalSubstance N-glycosylnicotinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25526 CHEBI:25524 biolink:ChemicalSubstance NAD(P) go-plus.json http://purl.obolibrary.org/obo/CHEBI_25524 NCBITaxon:181550 biolink:OrganismalEntity Trichomonadidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_181550 UBERON:0036521 biolink:AnatomicalEntity wall of urethra go-plus.json urethral wall http://purl.obolibrary.org/obo/UBERON_0036521 CL:1000428 biolink:Cell stem cell of epidermis A somatic stem cell that is part of the epidermis. go-plus.json epidermal stem cell http://purl.obolibrary.org/obo/CL_1000428 CL:1000427 biolink:Cell adrenal cortex chromaffin cell A chromaffin cell that is part of the adrenal cortex. go-plus.json chromaffin cell of adrenal cortex http://purl.obolibrary.org/obo/CL_1000427 UBERON:0036523 biolink:AnatomicalEntity wall of vagina go-plus.json vaginal wall http://purl.obolibrary.org/obo/UBERON_0036523 CL:1000426 biolink:Cell chromaffin cell of adrenal gland A chromaffin cell that is part of the adrenal gland. go-plus.json adrenal chromaffin cell http://purl.obolibrary.org/obo/CL_1000426 CL:0002178 biolink:Cell epithelial cell of stomach An epithelial cell found in the lining of the stomach. go-plus.json http://purl.obolibrary.org/obo/CL_0002178 CHEBI:74572 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z)-3-oxooctatriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74572 CHEBI:25529 biolink:ChemicalSubstance pyridinecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25529 NCBITaxon:3880 biolink:OrganismalEntity Medicago truncatula go-plus.json barrel medic http://purl.obolibrary.org/obo/NCBITaxon_3880 CHEBI:74574 biolink:ChemicalSubstance pentadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74574 CHEBI:74576 biolink:ChemicalSubstance 1-acyl-2-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-sn-glycero-3-phospho-D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_74576 CL:0002174 biolink:Cell follicular cell of ovary A cell within the follicle of an ovary. go-plus.json http://purl.obolibrary.org/obo/CL_0002174 CHEBI:74575 biolink:ChemicalSubstance (9Z)-pentadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74575 GO:0072177 biolink:BiologicalProcess mesonephric duct development The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. go-plus.json Wolffian duct development http://purl.obolibrary.org/obo/GO_0072177 GO:0072176 biolink:BiologicalProcess nephric duct development The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072176 GO:0072175 biolink:BiologicalProcess epithelial tube formation The developmental process pertaining to the initial formation of an epithelial tube. go-plus.json http://purl.obolibrary.org/obo/GO_0072175 GO:0072174 biolink:BiologicalProcess metanephric tubule formation The developmental process pertaining to the initial formation of a metanephric tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072174 GO:0072173 biolink:BiologicalProcess metanephric tubule morphogenesis The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072173 GO:0072172 biolink:BiologicalProcess mesonephric tubule formation The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072172 GO:0072171 biolink:BiologicalProcess mesonephric tubule morphogenesis The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072171 GO:0072170 biolink:BiologicalProcess metanephric tubule development The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072170 CHEBI:132883 biolink:ChemicalSubstance 11(S),15(S)-dihydroxy-14(R)-(S-glutathionyl)-5(Z),8(Z),12(E)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132883 CHEBI:132886 biolink:ChemicalSubstance 11(S)-hydroxy-14(S),15(S)-hepoxilin A3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132886 GO:0072179 biolink:BiologicalProcess nephric duct formation The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072179 GO:0072178 biolink:BiologicalProcess nephric duct morphogenesis The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072178 GO:0072166 biolink:BiologicalProcess posterior mesonephric tubule development The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072166 GO:0072165 biolink:BiologicalProcess anterior mesonephric tubule development The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072165 GO:0072164 biolink:BiologicalProcess mesonephric tubule development The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072164 GO:0072163 biolink:BiologicalProcess mesonephric epithelium development The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072163 GO:0072162 biolink:BiologicalProcess metanephric mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072162 GO:0072161 biolink:BiologicalProcess mesenchymal cell differentiation involved in kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072161 GO:0072160 biolink:BiologicalProcess nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072160 CHEBI:142209 biolink:ChemicalSubstance pyrimidine 2'-deoxyribonucleoside 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142209 chebi_ph7_3 GO:0072169 biolink:BiologicalProcess specification of posterior mesonephric tubule identity The process in which the tubules of the posterior mesonephros acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072169 GO:0072168 biolink:BiologicalProcess specification of anterior mesonephric tubule identity The process in which the tubules of the anterior mesonephros acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072168 GO:0072167 biolink:BiologicalProcess specification of mesonephric tubule identity The process in which the tubules of the mesonephros acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072167 GO:0072199 biolink:BiologicalProcess regulation of mesenchymal cell proliferation involved in ureter development Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json regulation of ureteral mesenchymal cell proliferation|regulation of ureter mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0072199 GO:0072198 biolink:BiologicalProcess mesenchymal cell proliferation involved in ureter development The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development. go-plus.json ureter mesenchymal cell proliferation|ureteral mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0072198 CHEBI:50599 biolink:ChemicalSubstance N(tele)-methyl-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50599 GO:0072197 biolink:BiologicalProcess ureter morphogenesis The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0072197 GO:0072196 biolink:BiologicalProcess proximal/distal pattern formation involved in pronephric nephron development The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros. go-plus.json pronephros proximal/distal pattern formation http://purl.obolibrary.org/obo/GO_0072196 GO:0072195 biolink:BiologicalProcess kidney smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072195 GO:0072194 biolink:BiologicalProcess kidney smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072194 GO:0072193 biolink:BiologicalProcess ureter smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter. go-plus.json http://purl.obolibrary.org/obo/GO_0072193 GO:0072192 biolink:BiologicalProcess ureter epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter. go-plus.json http://purl.obolibrary.org/obo/GO_0072192 GO:0072191 biolink:BiologicalProcess ureter smooth muscle development The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072191 GO:0072190 biolink:BiologicalProcess ureter urothelium development The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter. go-plus.json ureter epithelium development http://purl.obolibrary.org/obo/GO_0072190 CHEBI:50591 biolink:ChemicalSubstance 4beta-methylzymosterol-4alpha-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50591 CHEBI:50593 biolink:ChemicalSubstance 3-dehydro-4-methylzymosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50593 chebi_ph7_3 GO:0072188 biolink:BiologicalProcess metanephric cap specification The process in which the metanephric cap acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072188 GO:0072187 biolink:BiologicalProcess metanephric cap formation The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. go-plus.json http://purl.obolibrary.org/obo/GO_0072187 GO:0072186 biolink:BiologicalProcess metanephric cap morphogenesis The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. go-plus.json http://purl.obolibrary.org/obo/GO_0072186 GO:0072185 biolink:BiologicalProcess metanephric cap development The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. go-plus.json http://purl.obolibrary.org/obo/GO_0072185 CHEBI:50586 biolink:ChemicalSubstance 9xi-episterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50586 chebi_ph7_3 GO:0072184 biolink:BiologicalProcess renal vesicle progenitor cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing. go-plus.json http://purl.obolibrary.org/obo/GO_0072184 GO:0072183 biolink:BiologicalProcess negative regulation of nephron tubule epithelial cell differentiation Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0072183 GO:0072182 biolink:BiologicalProcess regulation of nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0072182 GO:0072181 biolink:BiologicalProcess mesonephric duct formation The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros. go-plus.json Wolffian duct formation http://purl.obolibrary.org/obo/GO_0072181 GO:0072180 biolink:BiologicalProcess mesonephric duct morphogenesis The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros. go-plus.json Wolffian duct morphogenesis http://purl.obolibrary.org/obo/GO_0072180 CHEBI:132877 biolink:ChemicalSubstance 4-O-[(2R)-1-glycerylphosphono]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132877 CHEBI:132876 biolink:ChemicalSubstance beta-D-glucosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132876 CHEBI:132875 biolink:ChemicalSubstance N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132875 CHEBI:50584 biolink:ChemicalSubstance alkyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50584 CHEBI:50583 biolink:ChemicalSubstance 3-hydroxyoctadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_50583 GO:0072189 biolink:BiologicalProcess ureter development The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. go-plus.json http://purl.obolibrary.org/obo/GO_0072189 CHEBI:50582 biolink:ChemicalSubstance alkenyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50582 CHEBI:50578 biolink:ChemicalSubstance 3-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50578 CHEBI:50576 biolink:ChemicalSubstance 3-oxooctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50576 CHEBI:50570 biolink:ChemicalSubstance trans-2-octadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_50570 CHEBI:50574 biolink:ChemicalSubstance octadec-2-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50574 chebi_ph7_3 CHEBI:50573 biolink:ChemicalSubstance octadec-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50573 CHEBI:50572 biolink:ChemicalSubstance trans-octadec-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50572 CHEBI:50571 biolink:ChemicalSubstance 3-oxooctadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_50571 CHEBI:50566 biolink:ChemicalSubstance nitric oxide donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50566 CHEBI:50565 biolink:ChemicalSubstance N-acetyl-beta-D-glucosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50565 CHEBI:49575 biolink:ChemicalSubstance diazepam go-plus.json http://purl.obolibrary.org/obo/CHEBI_49575 chebi_ph7_3 UBERON:0012504 biolink:AnatomicalEntity adventitia of esophagus A adventitia that is part of a esophagus. go-plus.json adventitia of oesophagus|esophageal adventitia|esophagus adventitia|adventitious layer of esophagus|tunica adventitia oesophageae|tunica adventitia (esophagus) http://purl.obolibrary.org/obo/UBERON_0012504 CHEBI:50563 biolink:ChemicalSubstance iridoid monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50563 CHEBI:50562 biolink:ChemicalSubstance tartrate salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_50562 CHEBI:25591 biolink:ChemicalSubstance norcoclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25591 CHEBI:50545 biolink:ChemicalSubstance trans-isoeugenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50545 chebi_ph7_3 CHEBI:50544 biolink:ChemicalSubstance (-)-menthofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_50544 chebi_ph7_3 CHEBI:50542 biolink:ChemicalSubstance menthofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_50542 chebi_ph7_3 CHEBI:50549 biolink:ChemicalSubstance (beta-D-ribofuranosyl)uric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50549 CHEBI:50547 biolink:ChemicalSubstance 3-(beta-D-ribofuranosyl)uric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50547 chebi_ph7_3 CHEBI:49552 biolink:ChemicalSubstance copper(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49552 chebi_ph7_3 CHEBI:132832 biolink:ChemicalSubstance (+)-alpha-gurjunene go-plus.json http://purl.obolibrary.org/obo/CHEBI_132832 chebi_ph7_3 CHEBI:50540 biolink:ChemicalSubstance (S)-cis-N-methylcanadine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50540 chebi_ph7_3 GO:0047133 biolink:MolecularActivity dimethylamine dehydrogenase activity Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine. RHEA:10204|MetaCyc:1.5.8.1-RXN|EC:1.5.8.1|UM-BBD_reactionID:r1380 go-plus.json DMADh activity|dimethylamine:electron-transferring flavoprotein oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047133 GO:0047132 biolink:MolecularActivity dihydrobenzophenanthridine oxidase activity Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine. EC:1.5.3.12|RHEA:16621|MetaCyc:1.5.3.12-RXN go-plus.json dihydrobenzophenanthridine:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047132 GO:0047131 biolink:MolecularActivity saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH. MetaCyc:1.5.1.9-RXN|KEGG_REACTION:R02313|EC:1.5.1.9|RHEA:24520|Reactome:R-HSA-70940 go-plus.json saccharopin dehydrogenase activity|NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)|aminoadipic semialdehyde synthase activity|dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming) http://purl.obolibrary.org/obo/GO_0047131 GO:0047130 biolink:MolecularActivity saccharopine dehydrogenase (NADP+, L-lysine-forming) activity Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH. MetaCyc:1.5.1.8-RXN|EC:1.5.1.8|RHEA:19373|Reactome:R-HSA-70938|KEGG_REACTION:R00716 go-plus.json N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)|L-lysine-alpha-ketoglutarate reductase activity|saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming) http://purl.obolibrary.org/obo/GO_0047130 GO:1904959 biolink:BiologicalProcess regulation of cytochrome-c oxidase activity Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity. go-plus.json regulation of cytochrome aa3 activity|regulation of cytochrome a3 activity|regulation of ferrocytochrome c oxidase|regulation of cytochrome c oxidase activity|regulation of caa3-type cytochrome c oxidase|regulation of cbb3-type cytochrome c oxidase|regulation of cytochrome oxidase activity|regulation of warburg's respiratory enzyme activity|regulation of ferrocytochrome-c:oxygen oxidoreductase|regulation of ba3-type cytochrome c oxidase|regulation of aa3-type cytochrome c oxidase|regulation of complex IV (mitochondrial electron transport) activity|regulation of indophenolase|regulation of indophenol oxidase|regulation of NADH cytochrome c oxidase http://purl.obolibrary.org/obo/GO_1904959 GO:1904958 biolink:BiologicalProcess positive regulation of midbrain dopaminergic neuron differentiation Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation. go-plus.json activation of midbrain DA neurogenesis|up-regulation of midbrain DA neurogenesis|up regulation of midbrain dopaminergic neuron differentiation|up regulation of DA neurogenesis from midbrain floor plate|up regulation of midbrain dopaminergic neuron production|activation of midbrain dopaminergic neuron production|activation of DA neurogenesis from midbrain floor plate|upregulation of mDA neuron differentiation|positive regulation of midbrain dopaminergic neuron production|positive regulation of DA neurogenesis from midbrain floor plate|positive regulation of midbrain DA neurogenesis|up regulation of midbrain DA neurogenesis|upregulation of midbrain dopaminergic neuron differentiation|activation of mDA neuron differentiation|up-regulation of mDA neuron differentiation|up-regulation of DA neurogenesis from midbrain floor plate|up-regulation of midbrain dopaminergic neuron production|up-regulation of midbrain dopaminergic neuron differentiation|activation of midbrain dopaminergic neuron differentiation|upregulation of midbrain DA neurogenesis|upregulation of DA neurogenesis from midbrain floor plate|upregulation of midbrain dopaminergic neuron production|positive regulation of mDA neuron differentiation|up regulation of mDA neuron differentiation http://purl.obolibrary.org/obo/GO_1904958 GO:1904957 biolink:BiologicalProcess negative regulation of midbrain dopaminergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation. go-plus.json downregulation of mDA neuron differentiation|downregulation of midbrain dopaminergic neuron production|downregulation of DA neurogenesis from midbrain floor plate|down regulation of mDA neuron differentiation|inhibition of mDA neuron differentiation|downregulation of midbrain dopaminergic neuron differentiation|down-regulation of midbrain DA neurogenesis|negative regulation of midbrain DA neurogenesis|down regulation of midbrain dopaminergic neuron differentiation|negative regulation of DA neurogenesis from midbrain floor plate|negative regulation of midbrain dopaminergic neuron production|down-regulation of midbrain dopaminergic neuron production|down-regulation of DA neurogenesis from midbrain floor plate|inhibition of midbrain dopaminergic neuron differentiation|downregulation of midbrain DA neurogenesis|inhibition of DA neurogenesis from midbrain floor plate|inhibition of midbrain dopaminergic neuron production|down regulation of midbrain DA neurogenesis|inhibition of midbrain DA neurogenesis|down-regulation of mDA neuron differentiation|negative regulation of mDA neuron differentiation|down-regulation of midbrain dopaminergic neuron differentiation|down regulation of midbrain dopaminergic neuron production|down regulation of DA neurogenesis from midbrain floor plate http://purl.obolibrary.org/obo/GO_1904957 GO:1904956 biolink:BiologicalProcess regulation of midbrain dopaminergic neuron differentiation Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation. go-plus.json regulation of midbrain dopaminergic neuron production|regulation of DA neurogenesis from midbrain floor plate|regulation of mDA neuron differentiation|regulation of midbrain DA neurogenesis http://purl.obolibrary.org/obo/GO_1904956 GO:1904955 biolink:BiologicalProcess planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation. go-plus.json Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt-JNK signaling pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|planar cell polarity pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in DA neurogenesis from midbrain floor plate|Wnt signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|PCP pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt-PCP signaling pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|PCP pathway involved in midbrain DA neurogenesis|planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|non-canonical Wnt-mediated midbrain DA neuron differentiation|Wnt-JNK signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-JNK signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron production|Wnt-PCP signaling pathway involved in midbrain DA neurogenesis|PCP pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|planar cell polarity pathway involved in midbrain dopaminergic neuron production|planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation http://purl.obolibrary.org/obo/GO_1904955 GO:1904954 biolink:BiologicalProcess canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. go-plus.json canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in midbrain DA neurogenesis|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|canonical Wnt-mediated midbrain DA neuron differentiation|canonical Wnt signaling pathway involved in mDA neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in mDA neuron differentiation|frizzled-1 receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|canonical Wnt signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway via beta-catenin involved in midbrain DA neurogenesis|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|frizzled-1 receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain DA neurogenesis|frizzled-1 receptor signaling pathway involved in DA neurogenesis from midbrain floor plate http://purl.obolibrary.org/obo/GO_1904954 GO:0047139 biolink:MolecularActivity glutathione-homocystine transhydrogenase activity Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine. MetaCyc:1.8.4.1-RXN|RHEA:11464|EC:1.8.4.1 go-plus.json glutathione:homocystine oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047139 GO:0047138 biolink:MolecularActivity obsolete aquacobalamin reductase activity OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+. MetaCyc:AQUACOBALAMIN-REDUCTASE-RXN|EC:1.16.1.3|RHEA:24472 go-plus.json NADH:cob(III)alamin oxidoreductase activity|NADH-linked aquacobalamin reductase activity|NADH2:cob(III)alamin oxidoreductase activity|aquocobalamin reductase activity|vitamin B12a reductase activity|B(12a) reductase activity|cob(II)alamin:NAD+ oxidoreductase activity|vitamin B(12a) reductase activity|B12a reductase activity http://purl.obolibrary.org/obo/GO_0047138 GO:1904953 biolink:BiologicalProcess Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. go-plus.json Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway involved in midbrain DA neurogenesis|frizzled signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in midbrain DA neurogenesis|Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|Wg signaling pathway involved in mDA neuron differentiation|Wingless signaling pathway involved in midbrain dopaminergic neuron production|Wingless signalling pathway involved in midbrain dopaminergic neuron production|Wg signalling pathway involved in mDA neuron differentiation|Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|Wingless signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway involved in midbrain DA neurogenesis|frizzled signalling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt signaling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway involved in mDA neuron differentiation|frizzled signalling pathway involved in midbrain dopaminergic neuron production|frizzled signaling pathway involved in midbrain DA neurogenesis|frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in mDA neuron differentiation|Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in midbrain DA neurogenesis|Wg signalling pathway involved in midbrain dopaminergic neuron production|Wingless signaling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-mediated midbrain DA neuron differentiation|Wg signalling pathway involved in midbrain DA neurogenesis|Wg signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway involved in mDA neuron differentiation|frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signaling pathway involved in midbrain dopaminergic neuron production|frizzled signalling pathway involved in midbrain DA neurogenesis http://purl.obolibrary.org/obo/GO_1904953 GO:1904952 biolink:BiologicalProcess hydroxycinnamic acid transport The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1904952 GO:0047137 biolink:MolecularActivity N-hydroxy-2-acetamidofluorene reductase activity Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+. EC:1.7.1.12|MetaCyc:1.7.1.12-RXN go-plus.json NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|2-acetamidofluorene:NAD(P)+ oxidoreductase activity|N-hydroxy-2-acetylaminofluorene reductase activity http://purl.obolibrary.org/obo/GO_0047137 GO:1904951 biolink:BiologicalProcess positive regulation of establishment of protein localization Any process that activates or increases the frequency, rate or extent of establishment of protein localization. go-plus.json positive regulation of protein positioning|up regulation of establishment of protein localization|activation of establishment of protein localization|up-regulation of protein recruitment|up-regulation of establishment of protein localisation|up-regulation of protein positioning|up-regulation of establishment of protein localization|upregulation of protein recruitment|upregulation of establishment of protein localisation|upregulation of protein positioning|upregulation of establishment of protein localization|up regulation of protein recruitment|activation of protein recruitment|positive regulation of protein recruitment|up regulation of establishment of protein localisation|up regulation of protein positioning|activation of establishment of protein localisation|positive regulation of establishment of protein localisation|activation of protein positioning http://purl.obolibrary.org/obo/GO_1904951 GO:0047136 biolink:MolecularActivity 4-(dimethylamino)phenylazoxybenzene reductase activity Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH. EC:1.7.1.11|KEGG_REACTION:R04303|RHEA:19789|MetaCyc:1.6.6.12-RXN go-plus.json 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity|NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|N,N-dimethyl-p-aminoazobenzene oxide reductase activity|NADPH-dependent DMAB N-oxide reductase activity|dimethylaminoazobenzene N-oxide reductase activity http://purl.obolibrary.org/obo/GO_0047136 GO:1904950 biolink:BiologicalProcess negative regulation of establishment of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. go-plus.json down-regulation of protein recruitment|negative regulation of protein recruitment|downregulation of establishment of protein localization|down-regulation of establishment of protein localisation|negative regulation of establishment of protein localisation|negative regulation of protein positioning|down-regulation of protein positioning|inhibition of protein recruitment|inhibition of establishment of protein localisation|down-regulation of establishment of protein localization|inhibition of protein positioning|inhibition of establishment of protein localization|down regulation of protein recruitment|down regulation of establishment of protein localisation|down regulation of protein positioning|downregulation of protein recruitment|downregulation of establishment of protein localisation|downregulation of protein positioning|down regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_1904950 GO:0047135 biolink:MolecularActivity bis-gamma-glutamylcystine reductase activity Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH. MetaCyc:1.6.4.9-RXN|EC:1.8.1.13|KEGG_REACTION:R02742|RHEA:11980 go-plus.json bis-g-glutamylcystine reductase (NADPH) activity|bis-gamma-glutamylcystine reductase (NADPH) activity|NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity|gamma-glutamylcysteine:NADP+ oxidoreductase activity|NADPH:bis-gamma-glutamylcysteine oxidoreductase activity|Bis-gamma-glutamylcystine reductase (NADPH) http://purl.obolibrary.org/obo/GO_0047135 GO:0047134 biolink:MolecularActivity protein-disulfide reductase (NAD(P)) activity Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+. MetaCyc:1.6.4.4-RXN|EC:1.8.1.8 go-plus.json insulin-glutathione transhydrogenase activity|protein-disulphide reductase activity|protein disulfide reductase (NAD(P)H) activity|disulfide reductase activity|protein disulphide reductase activity|protein-disulfide reductase activity|protein disulfide reductase activity|NAD(P)H:protein-disulfide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047134 GO:0047144 biolink:MolecularActivity 2-acylglycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA. Reactome:R-HSA-1482635|Reactome:R-HSA-1482626|Reactome:R-HSA-1482646|Reactome:R-HSA-1482533|MetaCyc:2-ACYL2.3.1.15-RXN|EC:2.3.1.52|Reactome:R-HSA-1482546|RHEA:14233|Reactome:R-HSA-1482691 go-plus.json 2-acylglycerophosphate acyltransferase activity|acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047144 GO:0047143 biolink:MolecularActivity chlorate reductase activity Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+). EC:1.97.1.1|MetaCyc:1.97.1.1-RXN|UM-BBD_reactionID:r0981|RHEA:16349|KEGG_REACTION:R03575 go-plus.json chlorite:acceptor oxidoreductase activity|chlorate reductase C http://purl.obolibrary.org/obo/GO_0047143 GO:0047142 biolink:MolecularActivity enzyme-thiol transhydrogenase (glutathione-disulfide) activity Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase. MetaCyc:1.8.4.7-RXN|EC:1.8.4.7 go-plus.json xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity|enzyme-thiol transhydrogenase (glutathione-disulphide) activity|xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity|glutathione-dependent thiol:disulfide oxidoreductase activity|thiol:disulfide oxidoreductase activity|[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity|thiol:disulphide oxidoreductase activity|enzyme-thiol transhydrogenase (oxidized-glutathione) activity http://purl.obolibrary.org/obo/GO_0047142 GO:0047141 biolink:MolecularActivity glutathione-cystine transhydrogenase activity Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine. MetaCyc:1.8.4.4-RXN|RHEA:12613|EC:1.8.4.4 go-plus.json NADPH-dependent GSH-cystine transhydrogenase|glutathione:cystine oxidoreductase|GSH-cystine transhydrogenase http://purl.obolibrary.org/obo/GO_0047141 GO:0047140 biolink:MolecularActivity glutathione-CoA-glutathione transhydrogenase activity Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione. MetaCyc:1.8.4.3-RXN|RHEA:13125|EC:1.8.4.3 go-plus.json coenzyme A:oxidized-glutathione oxidoreductase activity|glutathione:coenzyme A-glutathione transhydrogenase activity|coenzyme A:glutathione-disulfide oxidoreductase activity|glutathione-coenzyme A glutathione disulfide transhydrogenase activity|glutathione coenzyme A-glutathione transhydrogenase activity|CoA:glutathione-disulfide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047140 GO:1904969 biolink:BiologicalProcess slow muscle cell migration The orderly movement of a slow muscle cell from one site to another. go-plus.json slow-twitch muscle cell migration http://purl.obolibrary.org/obo/GO_1904969 GO:1904968 biolink:BiologicalProcess positive regulation of monopolar spindle attachment to meiosis I kinetochore Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation. go-plus.json up-regulation of sister kinetochore mono-orientation|activation of attachment of spindle microtubules to kinetochore during meiosis I|up-regulation of monopolar attachment|upregulation of attachment of spindle microtubules to kinetochore involved in meiosis I|activation of monopolar attachment|up-regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|positive regulation of attachment of spindle microtubules to kinetochore during meiosis I|upregulation of sister kinetochore mono-orientation|up regulation of attachment of spindle microtubules to kinetochore during meiosis I|positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|positive regulation of monopolar attachment|positive regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|activation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up regulation of monopolar attachment|up regulation of sister kinetochore mono-orientation|upregulation of attachment of spindle microtubules to kinetochore during meiosis I|activation of sister kinetochore mono-orientation|positive regulation of sister kinetochore mono-orientation|up regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up-regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of monopolar attachment|activation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up-regulation of attachment of spindle microtubules to kinetochore during meiosis I http://purl.obolibrary.org/obo/GO_1904968 GO:1904967 biolink:BiologicalProcess regulation of monopolar spindle attachment to meiosis I kinetochore Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation. go-plus.json regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|regulation of attachment of spindle microtubules to kinetochore during meiosis I|regulation of sister kinetochore mono-orientation|correction of merotelic kinetochore attachment, meiosis I|regulation of monopolar attachment|repair of merotelic kinetochore attachment defect, meiosis I http://purl.obolibrary.org/obo/GO_1904967 GO:1904966 biolink:BiologicalProcess positive regulation of vitamin E biosynthetic process Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process. go-plus.json activation of vitamin E synthesis|positive regulation of vitamin E synthesis|up regulation of vitamin E formation|positive regulation of vitamin E biosynthesis|activation of vitamin E formation|positive regulation of vitamin E formation|up regulation of vitamin E biosynthesis|up regulation of vitamin E biosynthetic process|up regulation of tocopherol biosynthetic process|upregulation of alpha-tocopherol biosynthetic process|upregulation of alpha-tocopherol biosynthesis|up regulation of tocopherol biosynthesis|up-regulation of vitamin E anabolism|positive regulation of tocopherol biosynthesis|positive regulation of tocopherol biosynthetic process|activation of tocopherol biosynthesis|activation of tocopherol biosynthetic process|up-regulation of vitamin E synthesis|upregulation of vitamin E biosynthesis|up-regulation of vitamin E formation|upregulation of vitamin E biosynthetic process|upregulation of vitamin E anabolism|up regulation of alpha-tocopherol biosynthesis|up regulation of alpha-tocopherol biosynthetic process|positive regulation of alpha-tocopherol biosynthetic process|positive regulation of alpha-tocopherol biosynthesis|up-regulation of tocopherol biosynthesis|up-regulation of tocopherol biosynthetic process|upregulation of vitamin E synthesis|up-regulation of vitamin E biosynthetic process|upregulation of vitamin E formation|activation of alpha-tocopherol biosynthetic process|up-regulation of vitamin E biosynthesis|activation of alpha-tocopherol biosynthesis|activation of vitamin E biosynthetic process|activation of vitamin E biosynthesis|up regulation of vitamin E anabolism|activation of vitamin E anabolism|upregulation of tocopherol biosynthesis|positive regulation of vitamin E anabolism|upregulation of tocopherol biosynthetic process|up-regulation of alpha-tocopherol biosynthesis|up-regulation of alpha-tocopherol biosynthetic process|up regulation of vitamin E synthesis http://purl.obolibrary.org/obo/GO_1904966 GO:1904965 biolink:BiologicalProcess regulation of vitamin E biosynthetic process Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process. go-plus.json regulation of tocopherol biosynthesis|regulation of tocopherol biosynthetic process|regulation of vitamin E biosynthesis|regulation of alpha-tocopherol biosynthesis|regulation of alpha-tocopherol biosynthetic process|regulation of vitamin E anabolism|regulation of vitamin E synthesis|regulation of vitamin E formation http://purl.obolibrary.org/obo/GO_1904965 GO:0047149 biolink:MolecularActivity thetin-homocysteine S-methyltransferase activity Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+). MetaCyc:2.1.1.3-RXN|KEGG_REACTION:R04153|EC:2.1.1.3|RHEA:22788 go-plus.json dimethylthetin-homocysteine methyltransferase activity|dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity|thetin-homocysteine methylpherase activity http://purl.obolibrary.org/obo/GO_0047149 GO:1904964 biolink:BiologicalProcess positive regulation of phytol biosynthetic process Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process. go-plus.json upregulation of phytol formation|upregulation of phytol biosynthesis|upregulation of phytol biosynthetic process|up-regulation of phytol anabolism|activation of phytol anabolism|up-regulation of phytol synthesis|activation of phytol synthesis|up-regulation of phytol formation|activation of phytol formation|up regulation of phytol biosynthesis|up regulation of phytol biosynthetic process|activation of phytol biosynthesis|activation of phytol biosynthetic process|positive regulation of phytol anabolism|positive regulation of phytol biosynthesis|up regulation of phytol anabolism|positive regulation of phytol synthesis|up regulation of phytol synthesis|positive regulation of phytol formation|up regulation of phytol formation|up-regulation of phytol biosynthetic process|up-regulation of phytol biosynthesis|upregulation of phytol anabolism|upregulation of phytol synthesis http://purl.obolibrary.org/obo/GO_1904964 GO:0047148 biolink:MolecularActivity methylamine-glutamate N-methyltransferase activity Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+). MetaCyc:2.1.1.21-RXN|EC:2.1.1.21|RHEA:15837|KEGG_REACTION:R01586 go-plus.json methylamine:L-glutamate N-methyltransferase activity|N-methylglutamate synthase activity|methylamine-glutamate methyltransferase activity http://purl.obolibrary.org/obo/GO_0047148 GO:1904963 biolink:BiologicalProcess regulation of phytol biosynthetic process Any process that modulates the frequency, rate or extent of phytol biosynthetic process. go-plus.json regulation of phytol biosynthesis|regulation of phytol anabolism|regulation of phytol synthesis|regulation of phytol formation http://purl.obolibrary.org/obo/GO_1904963 GO:0047147 biolink:MolecularActivity trimethylsulfonium-tetrahydrofolate N-methyltransferase activity Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+). EC:2.1.1.19|MetaCyc:2.1.1.19-RXN|KEGG_REACTION:R02573|RHEA:13693 go-plus.json trimethylsulfonium-tetrahydrofolate methyltransferase activity|trimethylsulphonium-tetrahydrofolate N-methyltransferase activity|trimethylsulfonium:tetrahydrofolate N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0047147 GO:1904962 biolink:BiologicalProcess plastid to vacuole vesicle-mediated transport The vesicle-mediated and directed movement of substances from plastid to vacuole. go-plus.json plastid to vacuolar carboxypeptidase Y vesicle-mediated transport http://purl.obolibrary.org/obo/GO_1904962 GO:0047146 biolink:MolecularActivity sterigmatocystin 7-O-methyltransferase activity Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine. RHEA:15561|MetaCyc:2.1.1.110-RXN|EC:2.1.1.110 go-plus.json sterigmatocystin methyltransferase activity|sterigmatocystin 8-O-methyltransferase activity|S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity|S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity|O-methyltransferase II activity http://purl.obolibrary.org/obo/GO_0047146 GO:1904961 biolink:BiologicalProcess quiescent center organization The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure. go-plus.json quiescent center structural organization http://purl.obolibrary.org/obo/GO_1904961 GO:1904960 biolink:BiologicalProcess positive regulation of cytochrome-c oxidase activity Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity. go-plus.json activation of aa3-type cytochrome c oxidase|up regulation of NADH cytochrome c oxidase|up-regulation of cytochrome c oxidase activity|up-regulation of ferrocytochrome c oxidase|activation of NADH cytochrome c oxidase|activation of cytochrome a3 activity|positive regulation of NADH cytochrome c oxidase|up-regulation of cytochrome oxidase activity|up-regulation of warburg's respiratory enzyme activity|activation of indophenolase|up-regulation of complex IV (mitochondrial electron transport) activity|up-regulation of ferrocytochrome-c:oxygen oxidoreductase|up-regulation of ba3-type cytochrome c oxidase|activation of caa3-type cytochrome c oxidase|activation of cbb3-type cytochrome c oxidase|up-regulation of aa3-type cytochrome c oxidase|upregulation of cytochrome aa3 activity|up-regulation of indophenol oxidase|positive regulation of cytochrome a3 activity|up regulation of cytochrome-c oxidase activity|activation of cytochrome-c oxidase activity|positive regulation of cbb3-type cytochrome c oxidase|up-regulation of indophenolase|positive regulation of caa3-type cytochrome c oxidase|activation of complex IV (mitochondrial electron transport) activity|up regulation of cytochrome a3 activity|upregulation of ferrocytochrome c oxidase|upregulation of cytochrome c oxidase activity|up regulation of caa3-type cytochrome c oxidase|up regulation of cbb3-type cytochrome c oxidase|upregulation of cytochrome oxidase activity|upregulation of warburg's respiratory enzyme activity|upregulation of ferrocytochrome-c:oxygen oxidoreductase|up-regulation of NADH cytochrome c oxidase|activation of indophenol oxidase|upregulation of ba3-type cytochrome c oxidase|positive regulation of complex IV (mitochondrial electron transport) activity|upregulation of aa3-type cytochrome c oxidase|up regulation of cytochrome aa3 activity|up regulation of complex IV (mitochondrial electron transport) activity|positive regulation of indophenol oxidase|positive regulation of cytochrome aa3 activity|upregulation of indophenolase|upregulation of cytochrome a3 activity|up regulation of ferrocytochrome c oxidase|up-regulation of cytochrome-c oxidase activity|up regulation of indophenol oxidase|up regulation of cytochrome c oxidase activity|upregulation of caa3-type cytochrome c oxidase|upregulation of cbb3-type cytochrome c oxidase|up regulation of cytochrome oxidase activity|up regulation of warburg's respiratory enzyme activity|positive regulation of cytochrome c oxidase activity|positive regulation of ferrocytochrome c oxidase|upregulation of NADH cytochrome c oxidase|activation of cytochrome c oxidase activity|up regulation of ba3-type cytochrome c oxidase|up regulation of ferrocytochrome-c:oxygen oxidoreductase|activation of cytochrome aa3 activity|positive regulation of warburg's respiratory enzyme activity|positive regulation of cytochrome oxidase activity|up regulation of aa3-type cytochrome c oxidase|positive regulation of ba3-type cytochrome c oxidase|positive regulation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of complex IV (mitochondrial electron transport) activity|positive regulation of aa3-type cytochrome c oxidase|activation of ferrocytochrome c oxidase|up-regulation of cytochrome a3 activity|up regulation of indophenolase|activation of cytochrome oxidase activity|up-regulation of cytochrome aa3 activity|upregulation of cytochrome-c oxidase activity|activation of warburg's respiratory enzyme activity|activation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of indophenol oxidase|up-regulation of cbb3-type cytochrome c oxidase|positive regulation of indophenolase|activation of ba3-type cytochrome c oxidase|up-regulation of caa3-type cytochrome c oxidase http://purl.obolibrary.org/obo/GO_1904960 GO:0047145 biolink:MolecularActivity demethylsterigmatocystin 6-O-methyltransferase activity Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine. RHEA:11504|MetaCyc:2.1.1.109-RXN|EC:2.1.1.109 go-plus.json O-methyltransferase I|demethylsterigmatocystin methyltransferase activity|S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0047145 GO:1904970 biolink:BiologicalProcess brush border assembly The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border. go-plus.json brush border formation http://purl.obolibrary.org/obo/GO_1904970 GO:0072111 biolink:BiologicalProcess cell proliferation involved in kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072111 GO:0047155 biolink:MolecularActivity 3-hydroxymethylcephem carbamoyltransferase activity Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem. MetaCyc:2.1.3.7-RXN|EC:2.1.3.7 go-plus.json 3'-hydroxymethylcephem-O-carbamoyltransferase activity|carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity http://purl.obolibrary.org/obo/GO_0047155 GO:0047154 biolink:MolecularActivity methylmalonyl-CoA carboxytransferase activity Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA. RHEA:20764|MetaCyc:2.1.3.1-RXN|EC:2.1.3.1|UM-BBD_reactionID:r0923 go-plus.json (S)-methylmalonyl-CoA:pyruvate carboxytransferase activity|methylmalonyl-CoA transcarboxylase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity|(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity|methylmalonyl-CoA carboxyltransferase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate|methylmalonyl coenzyme A carboxyltransferase activity|transcarboxylase activity|oxalacetic transcarboxylase activity http://purl.obolibrary.org/obo/GO_0047154 GO:0072110 biolink:BiologicalProcess glomerular mesangial cell proliferation The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population. go-plus.json http://purl.obolibrary.org/obo/GO_0072110 GO:0047153 biolink:MolecularActivity deoxycytidylate 5-hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate. MetaCyc:2.1.2.8-RXN|EC:2.1.2.8|RHEA:11280|KEGG_REACTION:R01669 go-plus.json 5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity|deoxycytidylate hydroxymethyltransferase activity|deoxycytidylic hydroxymethylase activity|deoxyCMP hydroxymethylase activity|deoxycytidylate hydroxymethylase activity|d-cytidine 5'-monophosphate hydroxymethylase activity|dCMP hydroxymethylase activity http://purl.obolibrary.org/obo/GO_0047153 GO:0047152 biolink:MolecularActivity methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide. RHEA:21344|EC:2.1.1.90|MetaCyc:2.1.1.90-RXN go-plus.json methanol:corrinoid methyltransferase activity|methyltransferase 1|MT1|methanol-corrinoid protein Co-methyltransferase|MtaB|methanol cobalamin methyltransferase activity|methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity|MT 1|methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity http://purl.obolibrary.org/obo/GO_0047152 GO:0047151 biolink:MolecularActivity methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+. EC:2.1.1.74|RHEA:16873|MetaCyc:2.1.1.74-RXN|KEGG_REACTION:R03704 go-plus.json 5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity|folate-dependent ribothymidyl synthase activity|methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity|5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity|methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity http://purl.obolibrary.org/obo/GO_0047151 GO:0047150 biolink:MolecularActivity betaine-homocysteine S-methyltransferase activity Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine. KEGG_REACTION:R02821|RHEA:22336|MetaCyc:2.1.1.5-RXN|EC:2.1.1.5|Reactome:R-HSA-1614654 go-plus.json betaine-homocysteine transmethylase activity|trimethylammonioacetate:L-homocysteine S-methyltransferase activity|betaine-homocysteine methyltransferase activity http://purl.obolibrary.org/obo/GO_0047150 GO:1904979 biolink:BiologicalProcess negative regulation of endosome organization Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization. go-plus.json down regulation of endosome organisation|downregulation of endosome organisation|down regulation of endosome organization|negative regulation of endosome organization and biogenesis|down-regulation of endosome organization and biogenesis|downregulation of endosome organization|down-regulation of endosome organisation|negative regulation of endosome organisation|downregulation of endosome organization and biogenesis|inhibition of endosome organisation|down-regulation of endosome organization|down regulation of endosome organization and biogenesis|inhibition of endosome organization|inhibition of endosome organization and biogenesis http://purl.obolibrary.org/obo/GO_1904979 GO:1904978 biolink:BiologicalProcess regulation of endosome organization Any process that modulates the frequency, rate or extent of endosome organization. go-plus.json regulation of endosome organisation|regulation of endosome organization and biogenesis http://purl.obolibrary.org/obo/GO_1904978 GO:1904977 biolink:BiologicalProcess lymphatic endothelial cell migration The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. go-plus.json http://purl.obolibrary.org/obo/GO_1904977 GO:1904976 biolink:BiologicalProcess cellular response to bleomycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904976 GO:1904975 biolink:BiologicalProcess response to bleomycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904975 GO:1904974 biolink:CellularComponent heparanase complex A protein complex which is capable of heparanase activity. go-plus.json HEPS complex http://purl.obolibrary.org/obo/GO_1904974 GO:0047159 biolink:MolecularActivity 1-alkenylglycerophosphocholine O-acyltransferase activity Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA. EC:2.3.1.25|RHEA:10344|MetaCyc:2.3.1.104-RXN go-plus.json acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047159 GO:0047158 biolink:MolecularActivity sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose. RHEA:22664|MetaCyc:2.3.1.103-RXN|KEGG_REACTION:R00063|EC:2.3.1.103 go-plus.json 1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity|1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity|hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity http://purl.obolibrary.org/obo/GO_0047158 GO:1904973 biolink:BiologicalProcess positive regulation of viral translation Any process that activates or increases the frequency, rate or extent of viral translation. go-plus.json up-regulation of viral protein synthesis|positive regulation of viral protein biosynthesis|positive regulation of viral protein biosynthetic process|up-regulation of viral protein formation|upregulation of viral protein anabolism|up regulation of viral protein biosynthesis|up regulation of viral protein biosynthetic process|up-regulation of viral translation|upregulation of viral protein synthesis|upregulation of viral protein formation|upregulation of viral protein biosynthesis|up regulation of viral protein anabolism|upregulation of viral translation|upregulation of viral protein biosynthetic process|activation of viral protein anabolism|positive regulation of viral protein anabolism|up regulation of viral protein synthesis|activation of viral protein synthesis|positive regulation of viral protein synthesis|up regulation of viral protein formation|activation of viral protein formation|activation of viral protein biosynthetic process|up-regulation of viral protein biosynthetic process|activation of viral protein biosynthesis|up-regulation of viral protein biosynthesis|positive regulation of viral protein formation|up regulation of viral translation|activation of viral translation|up-regulation of viral protein anabolism http://purl.obolibrary.org/obo/GO_1904973 GO:1904972 biolink:BiologicalProcess negative regulation of viral translation Any process that stops, prevents or reduces the frequency, rate or extent of viral translation. go-plus.json down-regulation of viral protein biosynthetic process|negative regulation of viral protein biosynthetic process|down-regulation of viral translation|down-regulation of viral protein biosynthesis|negative regulation of viral protein biosynthesis|inhibition of viral protein synthesis|inhibition of viral protein formation|inhibition of viral translation|down regulation of viral protein anabolism|downregulation of viral protein biosynthetic process|downregulation of viral protein biosynthesis|down regulation of viral protein synthesis|downregulation of viral protein anabolism|down regulation of viral protein biosynthesis|down regulation of viral protein biosynthetic process|inhibition of viral protein biosynthetic process|inhibition of viral protein biosynthesis|down regulation of viral protein formation|downregulation of viral protein synthesis|down regulation of viral translation|downregulation of viral protein formation|negative regulation of viral protein anabolism|down-regulation of viral protein anabolism|downregulation of viral translation|negative regulation of viral protein synthesis|down-regulation of viral protein synthesis|negative regulation of viral protein formation|down-regulation of viral protein formation|inhibition of viral protein anabolism http://purl.obolibrary.org/obo/GO_1904972 GO:0047157 biolink:MolecularActivity myelin-proteolipid O-palmitoyltransferase activity Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA. MetaCyc:2.3.1.100-RXN|EC:2.3.1.100 go-plus.json [myelin-proteolipid] O-palmitoyltransferase activity|acyl-protein synthase activity|palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity|myelin PLP acyltransferase activity http://purl.obolibrary.org/obo/GO_0047157 GO:0047156 biolink:MolecularActivity acetoin-ribose-5-phosphate transaldolase activity Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde. RHEA:21504|KEGG_REACTION:R02345|MetaCyc:2.2.1.4-RXN|EC:2.2.1.4 go-plus.json 3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity|3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity|1-deoxy-D-altro-heptulose-7-phosphate synthetase activity|1-deoxy-D-altro-heptulose-7-phosphate synthase activity http://purl.obolibrary.org/obo/GO_0047156 GO:1904971 biolink:BiologicalProcess regulation of viral translation Any process that modulates the frequency, rate or extent of viral translation. go-plus.json regulation of viral protein biosynthetic process|regulation of viral protein anabolism|regulation of viral protein biosynthesis|regulation of viral protein synthesis|regulation of viral protein formation http://purl.obolibrary.org/obo/GO_1904971 GO:1904981 biolink:BiologicalProcess maltose transmembrane transport The process in which maltose is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904981 GO:1904980 biolink:BiologicalProcess positive regulation of endosome organization Any process that activates or increases the frequency, rate or extent of endosome organization. go-plus.json upregulation of endosome organization and biogenesis|up-regulation of endosome organization|upregulation of endosome organisation|up-regulation of endosome organization and biogenesis|upregulation of endosome organization|up regulation of endosome organisation|positive regulation of endosome organisation|activation of endosome organisation|activation of endosome organization and biogenesis|up regulation of endosome organization|positive regulation of endosome organization and biogenesis|up regulation of endosome organization and biogenesis|activation of endosome organization|up-regulation of endosome organisation http://purl.obolibrary.org/obo/GO_1904980 GO:0072119 biolink:BiologicalProcess head kidney structural organization The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. go-plus.json head kidney structural organisation http://purl.obolibrary.org/obo/GO_0072119 GO:0072118 biolink:BiologicalProcess pronephros structural organization The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. go-plus.json pronephros structural organisation|pronephric kidney structural organization http://purl.obolibrary.org/obo/GO_0072118 GO:0072117 biolink:BiologicalProcess head kidney formation The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072117 GO:0072116 biolink:BiologicalProcess pronephros formation The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. go-plus.json pronephric kidney formation http://purl.obolibrary.org/obo/GO_0072116 GO:0072115 biolink:BiologicalProcess head kidney morphogenesis The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072115 GO:0072114 biolink:BiologicalProcess pronephros morphogenesis The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. go-plus.json pronephric kidney morphogenesis http://purl.obolibrary.org/obo/GO_0072114 SO:0001700 biolink:SequenceFeature histone_modification Histone modification is a post translationally modified region whereby residues of the histone protein are modified by methylation, acetylation, phosphorylation, ubiquitination, sumoylation, citrullination, or ADP-ribosylation. go-plus.json histone modification|histone modification site http://purl.obolibrary.org/obo/SO_0001700 GO:0072113 biolink:BiologicalProcess head kidney development The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072113 GO:0072112 biolink:BiologicalProcess glomerular visceral epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. go-plus.json podocyte differentiation http://purl.obolibrary.org/obo/GO_0072112 GO:0072100 biolink:BiologicalProcess specification of ureteric bud anterior/posterior symmetry The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis. go-plus.json specification of ureteric bud anterior/posterior asymmetry http://purl.obolibrary.org/obo/GO_0072100 GO:0047166 biolink:MolecularActivity 1-alkenylglycerophosphoethanolamine O-acyltransferase activity Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA. EC:2.3.1.121|RHEA:16245|MetaCyc:2.3.1.121-RXN go-plus.json acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047166 GO:0047165 biolink:MolecularActivity flavonol-3-O-beta-glucoside O-malonyltransferase activity Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA. MetaCyc:2.3.1.116-RXN|RHEA:20085|EC:2.3.1.116 go-plus.json malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|MAT-3|flavonol 3-O-glucoside malonyltransferase activity|malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity http://purl.obolibrary.org/obo/GO_0047165 GO:0047164 biolink:MolecularActivity isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA. MetaCyc:2.3.1.115-RXN|EC:2.3.1.115|RHEA:15581 go-plus.json flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity|malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity|flavone (flavonol) 7-O-glycoside malonyltransferase activity|malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity|MAT-7|malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity|malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity http://purl.obolibrary.org/obo/GO_0047164 GO:0047163 biolink:MolecularActivity 3,4-dichloroaniline N-malonyltransferase activity Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA. MetaCyc:2.3.1.114-RXN|EC:2.3.1.114|RHEA:21060|KEGG_REACTION:R04050 go-plus.json malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity http://purl.obolibrary.org/obo/GO_0047163 GO:0047162 biolink:MolecularActivity 17-O-deacetylvindoline O-acetyltransferase activity Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA. MetaCyc:2.3.1.107-RXN|EC:2.3.1.107|RHEA:24496|KEGG_REACTION:R03230 go-plus.json acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity|DAT activity|acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity|deacetylvindoline acetyltransferase activity|deacetylvindoline O-acetyltransferase activity|17-O-deacetylvindoline-17-O-acetyltransferase activity|acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity|acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity|acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity|acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047162 GO:0047161 biolink:MolecularActivity tartronate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate. KEGG_REACTION:R03965|RHEA:10952|MetaCyc:2.3.1.106-RXN|EC:2.3.1.106 go-plus.json tartronate sinapoyltransferase activity|sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity|hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity http://purl.obolibrary.org/obo/GO_0047161 GO:0047160 biolink:MolecularActivity alkylglycerophosphate 2-O-acetyltransferase activity Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA. MetaCyc:2.3.1.105-RXN|KEGG_REACTION:R03455|RHEA:18557|EC:2.3.1.105 go-plus.json acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity|alkyllyso-GP:acetyl-CoA acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047160 GO:1904989 biolink:BiologicalProcess positive regulation of endothelial cell activation Any process that activates or increases the frequency, rate or extent of endothelial cell activation. go-plus.json upregulation of endothelial cell activation|up regulation of endothelial cell activation|activation of endothelial cell activation|up-regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_1904989 GO:1904988 biolink:BiologicalProcess negative regulation of endothelial cell activation Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. go-plus.json down regulation of endothelial cell activation|downregulation of endothelial cell activation|down-regulation of endothelial cell activation|inhibition of endothelial cell activation http://purl.obolibrary.org/obo/GO_1904988 GO:1904987 biolink:BiologicalProcess regulation of endothelial cell activation Any process that modulates the frequency, rate or extent of endothelial cell activation. go-plus.json http://purl.obolibrary.org/obo/GO_1904987 GO:1904986 biolink:BiologicalProcess positive regulation of quinolinate biosynthetic process Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process. go-plus.json upregulation of quinolinate synthesis|up-regulation of quinolinate biosynthetic process|upregulation of quinolinate formation|up-regulation of quinolinate biosynthesis|activation of quinolinate biosynthetic process|activation of quinolinate biosynthesis|up regulation of quinolinate anabolism|positive regulation of quinolinate anabolism|activation of quinolinate anabolism|up regulation of quinolinate synthesis|positive regulation of quinolinate synthesis|activation of quinolinate synthesis|up regulation of quinolinate formation|positive regulation of quinolinate biosynthesis|positive regulation of quinolinate formation|activation of quinolinate formation|up regulation of quinolinate biosynthesis|up regulation of quinolinate biosynthetic process|up-regulation of quinolinate anabolism|up-regulation of quinolinate synthesis|upregulation of quinolinate biosynthesis|upregulation of quinolinate biosynthetic process|up-regulation of quinolinate formation|upregulation of quinolinate anabolism http://purl.obolibrary.org/obo/GO_1904986 GO:1904985 biolink:BiologicalProcess negative regulation of quinolinate biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process. go-plus.json down regulation of quinolinate anabolism|downregulation of quinolinate anabolism|down regulation of quinolinate synthesis|down regulation of quinolinate formation|downregulation of quinolinate synthesis|down-regulation of quinolinate biosynthesis|down-regulation of quinolinate biosynthetic process|negative regulation of quinolinate biosynthesis|downregulation of quinolinate formation|down-regulation of quinolinate anabolism|negative regulation of quinolinate anabolism|down-regulation of quinolinate synthesis|negative regulation of quinolinate synthesis|inhibition of quinolinate anabolism|downregulation of quinolinate biosynthesis|down-regulation of quinolinate formation|negative regulation of quinolinate formation|downregulation of quinolinate biosynthetic process|inhibition of quinolinate synthesis|down regulation of quinolinate biosynthesis|down regulation of quinolinate biosynthetic process|inhibition of quinolinate biosynthetic process|inhibition of quinolinate biosynthesis|inhibition of quinolinate formation http://purl.obolibrary.org/obo/GO_1904985 GO:1904984 biolink:BiologicalProcess regulation of quinolinate biosynthetic process Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process. go-plus.json regulation of quinolinate anabolism|regulation of quinolinate synthesis|regulation of quinolinate formation|regulation of quinolinate biosynthesis http://purl.obolibrary.org/obo/GO_1904984 GO:0047169 biolink:MolecularActivity galactarate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA. EC:2.3.1.130|KEGG_REACTION:R03727|RHEA:12997|MetaCyc:2.3.1.130-RXN go-plus.json galacturate hydroxycinnamoyltransferase activity|feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047169 GO:0047168 biolink:MolecularActivity isocitrate O-dihydroxycinnamoyltransferase activity Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA. KEGG_REACTION:R01946|RHEA:20756|MetaCyc:2.3.1.126-RXN|EC:2.3.1.126 go-plus.json caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047168 GO:1904983 biolink:BiologicalProcess glycine import into mitochondrion The process in which glycine is transported from the cytosol into the mitochondrial matrix. go-plus.json transmembrane glycine transport from cytosol to mitochondrion http://purl.obolibrary.org/obo/GO_1904983 GO:1904982 biolink:BiologicalProcess sucrose transmembrane transport The process in which sucrose is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904982 GO:0047167 biolink:MolecularActivity 1-alkyl-2-acetylglycerol O-acyltransferase activity Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA. RHEA:21996|MetaCyc:2.3.1.125-RXN|EC:2.3.1.125 go-plus.json acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity|1-hexadecyl-2-acetylglycerol acyltransferase activity http://purl.obolibrary.org/obo/GO_0047167 GO:1904992 biolink:BiologicalProcess positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway. go-plus.json activation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|positive regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|activation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|activation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|upregulation of dopamine receptor, adenylate cyclase inhibiting pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|upregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|up regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up regulation of dopamine receptor, adenylate cyclase inhibiting pathway|activation of dopamine receptor, adenylate cyclase inhibiting pathway|positive regulation of dopamine receptor, adenylate cyclase inhibiting pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|activation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway http://purl.obolibrary.org/obo/GO_1904992 GO:1904991 biolink:BiologicalProcess negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway. go-plus.json inhibition of dopamine receptor, adenylate cyclase inhibiting pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|downregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|down regulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|downregulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|downregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|negative regulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|negative regulation of dopamine receptor, adenylyl cyclase inhibiting pathway http://purl.obolibrary.org/obo/GO_1904991 GO:1904990 biolink:BiologicalProcess regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway. go-plus.json regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|regulation of dopamine receptor, adenylate cyclase inhibiting pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway http://purl.obolibrary.org/obo/GO_1904990 GO:0072109 biolink:BiologicalProcess glomerular mesangium development The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072109 GO:0072108 biolink:BiologicalProcess positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072108 GO:0072107 biolink:BiologicalProcess positive regulation of ureteric bud formation Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. go-plus.json http://purl.obolibrary.org/obo/GO_0072107 GO:0072106 biolink:BiologicalProcess regulation of ureteric bud formation Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. go-plus.json http://purl.obolibrary.org/obo/GO_0072106 GO:0072105 biolink:BiologicalProcess ureteric peristalsis A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0072105 GO:0072104 biolink:BiologicalProcess glomerular capillary formation The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0072104 GO:0072103 biolink:BiologicalProcess glomerulus vasculature morphogenesis The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072103 GO:0072102 biolink:BiologicalProcess glomerulus morphogenesis The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072102 GO:0072101 biolink:BiologicalProcess specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis. go-plus.json specification of ureteric bud anterior/posterior symmetry by BMP signalling pathway|specification of ureteric bud anterior/posterior asymmetry by BMP signaling pathway http://purl.obolibrary.org/obo/GO_0072101 GO:0072133 biolink:BiologicalProcess metanephric mesenchyme morphogenesis The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072133 GO:0047177 biolink:MolecularActivity glycerophospholipid arachidonoyl-transferase (CoA-independent) activity Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine. MetaCyc:2.3.1.147-RXN|EC:2.3.1.147|RHEA:15409 go-plus.json 1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)|1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent) http://purl.obolibrary.org/obo/GO_0047177 GO:0047176 biolink:MolecularActivity beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose. RHEA:19109|KEGG_REACTION:R04498|MetaCyc:2.3.1.143-RXN|EC:2.3.1.143 go-plus.json beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity|beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity|beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity|1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity http://purl.obolibrary.org/obo/GO_0047176 GO:0072132 biolink:BiologicalProcess mesenchyme morphogenesis The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072132 GO:0047175 biolink:MolecularActivity galactosylacylglycerol O-acyltransferase activity Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein]. RHEA:17057|MetaCyc:2.3.1.141-RXN|EC:2.3.1.141 go-plus.json acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity|acyl-ACP:lyso-MGDG acyltransferase activity|acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity http://purl.obolibrary.org/obo/GO_0047175 GO:0072131 biolink:BiologicalProcess kidney mesenchyme morphogenesis The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072131 GO:0047174 biolink:MolecularActivity putrescine N-hydroxycinnamoyltransferase activity Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+). RHEA:12436|MetaCyc:2.3.1.138-RXN|EC:2.3.1.138|KEGG_REACTION:R01944 go-plus.json hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity|PHT|caffeoyl-CoA putrescine N-caffeoyl transferase activity|putrescine hydroxycinnamoyltransferase activity|putrescine hydroxycinnamoyl transferase activity|caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047174 GO:0072130 biolink:BiologicalProcess renal capsule specification The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0072130 GO:0047173 biolink:MolecularActivity phosphatidylcholine-retinol O-acyltransferase activity Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine. Reactome:R-HSA-975608|RHEA:17469|MetaCyc:2.3.1.135-RXN|EC:2.3.1.135 go-plus.json lecithin--retinol acyltransferase activity|phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity|phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047173 GO:0047172 biolink:MolecularActivity shikimate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA. RHEA:12124|MetaCyc:2.3.1.133-RXN|EC:2.3.1.133 go-plus.json shikimate hydroxycinnamoyltransferase activity|4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047172 GO:0047171 biolink:MolecularActivity glucarolactone O-hydroxycinnamoyltransferase activity Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA. MetaCyc:2.3.1.132-RXN|RHEA:14261|EC:2.3.1.132 go-plus.json sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047171 GO:0047170 biolink:MolecularActivity glucarate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA. MetaCyc:2.3.1.131-RXN|EC:2.3.1.131|RHEA:23308|KEGG_REACTION:R02899 go-plus.json sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047170 GO:1904999 biolink:BiologicalProcess positive regulation of leukocyte adhesion to arterial endothelial cell Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. go-plus.json upregulation of leukocyte adhesion to arterial endothelial cell|up regulation of leukocyte adhesion to arterial endothelial cell|activation of leukocyte adhesion to arterial endothelial cell|up-regulation of leukocyte adhesion to arterial endothelial cell http://purl.obolibrary.org/obo/GO_1904999 GO:1904998 biolink:BiologicalProcess negative regulation of leukocyte adhesion to arterial endothelial cell Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. go-plus.json down regulation of leukocyte adhesion to arterial endothelial cell|downregulation of leukocyte adhesion to arterial endothelial cell|down-regulation of leukocyte adhesion to arterial endothelial cell|inhibition of leukocyte adhesion to arterial endothelial cell http://purl.obolibrary.org/obo/GO_1904998 GO:1904997 biolink:BiologicalProcess regulation of leukocyte adhesion to arterial endothelial cell Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_1904997 GO:1904996 biolink:BiologicalProcess positive regulation of leukocyte adhesion to vascular endothelial cell Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. go-plus.json upregulation of leukocyte adhesion to vascular endothelial cell|up regulation of leukocyte adhesion to vascular endothelial cell|activation of leukocyte adhesion to vascular endothelial cell|up-regulation of leukocyte adhesion to vascular endothelial cell http://purl.obolibrary.org/obo/GO_1904996 GO:1904995 biolink:BiologicalProcess negative regulation of leukocyte adhesion to vascular endothelial cell Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. go-plus.json down regulation of leukocyte adhesion to vascular endothelial cell|downregulation of leukocyte adhesion to vascular endothelial cell|down-regulation of leukocyte adhesion to vascular endothelial cell|inhibition of leukocyte adhesion to vascular endothelial cell http://purl.obolibrary.org/obo/GO_1904995 GO:1904994 biolink:BiologicalProcess regulation of leukocyte adhesion to vascular endothelial cell Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_1904994 GO:0047179 biolink:MolecularActivity platelet-activating factor acetyltransferase activity Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid. RHEA:11048|MetaCyc:2.3.1.149-RXN|EC:2.3.1.149 go-plus.json 1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity|PAF acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047179 GO:1904993 biolink:BiologicalProcess obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle OBSOLETE. Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in positive regulation of G2/M transition of mitotic cell cycle. go-plus.json upregulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|activation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|positive regulation of CDK activity involved in positive regulation of mitotic entry|up regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|positive regulation of CDK activity involved in positive regulation of G2/M transition of mitotic cell cycle|activation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of mitotic entry|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|upregulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry http://purl.obolibrary.org/obo/GO_1904993 GO:0047178 biolink:MolecularActivity glycerophospholipid acyltransferase (CoA-dependent) activity Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine. RHEA:20972|MetaCyc:2.3.1.148-RXN|EC:2.3.1.148 go-plus.json 1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent) http://purl.obolibrary.org/obo/GO_0047178 GO:0047180 biolink:MolecularActivity salutaridinol 7-O-acetyltransferase activity Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA. RHEA:22856|KEGG_REACTION:R04723|MetaCyc:2.3.1.150-RXN|EC:2.3.1.150 go-plus.json acetyl-CoA:salutaridinol 7-O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047180 GO:0072139 biolink:BiologicalProcess glomerular parietal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0072139 GO:0072138 biolink:BiologicalProcess mesenchymal cell proliferation involved in ureteric bud development The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development. go-plus.json ureteric bud mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0072138 GO:0072137 biolink:BiologicalProcess condensed mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072137 SO:0001720 biolink:SequenceFeature epigenetically_modified_region A biological DNA region implicated in epigenomic changes caused by mechanisms other than changes in the underlying DNA sequence. This includes, nucleosomal histone post-translational modifications, nucleosome depletion to render DNA accessible and post-replicational base modifications such as cytosine modification. go-plus.json epigenetically modified region http://purl.obolibrary.org/obo/SO_0001720 SOFA GO:0072136 biolink:BiologicalProcess metanephric mesenchymal cell proliferation involved in metanephros development The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0072136 GO:0072135 biolink:BiologicalProcess kidney mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072135 GO:0072134 biolink:BiologicalProcess nephrogenic mesenchyme morphogenesis The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. go-plus.json http://purl.obolibrary.org/obo/GO_0072134 GO:0047188 biolink:MolecularActivity aromatic-hydroxylamine O-acetyltransferase activity Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl. EC:2.3.1.56|RHEA:20325|MetaCyc:2.3.1.56-RXN go-plus.json arylhydroxamate acyltransferase activity|N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity|N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity|arylhydroxamic acid N,O-acetyltransferase activity|aromatic hydroxylamine acetyltransferase activity|arylhydroxamic acyltransferase activity|N,O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047188 GO:0072122 biolink:BiologicalProcess extraglomerular mesangial cell proliferation The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. go-plus.json Goormaghtigh proliferation|lacis cell proliferation http://purl.obolibrary.org/obo/GO_0072122 GO:0047187 biolink:MolecularActivity deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate. EC:2.3.1.49|RHEA:20393|MetaCyc:2.3.1.49-RXN go-plus.json deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity|S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity|S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity|deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047187 GO:0072121 biolink:BiologicalProcess head kidney maturation A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072121 GO:0047186 biolink:MolecularActivity N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA. RHEA:20808|EC:2.3.1.45|MetaCyc:2.3.1.45-RXN go-plus.json acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity|N-acetylneuraminate 7(8)-O-acetyltransferase activity|glycoprotein 7(9)-O-acetyltransferase activity|N-acetylneuraminate O7-(or O9-)acetyltransferase activity|sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity|N-acetylneuraminate 7,8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047186 GO:0072120 biolink:BiologicalProcess pronephros maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. go-plus.json pronephric kidney maturation http://purl.obolibrary.org/obo/GO_0072120 GO:0047185 biolink:MolecularActivity N-acetylneuraminate 4-O-acetyltransferase activity Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA. KEGG_REACTION:R01806|EC:2.3.1.44|RHEA:18305|MetaCyc:2.3.1.44-RXN go-plus.json sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047185 GO:0047184 biolink:MolecularActivity 1-acylglycerophosphocholine O-acyltransferase activity Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA. RHEA:12937|EC:2.3.1.23|Reactome:R-HSA-1482794|MetaCyc:2.3.1.23-RXN go-plus.json acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity|lysophosphatidylcholine acyltransferase activity|lysolecithin acyltransferase activity|acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity|acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity|1-acyl-sn-glycero-3-phosphocholine acyltransferase activity|lysophosphatide acyltransferase activity http://purl.obolibrary.org/obo/GO_0047184 GO:0047183 biolink:MolecularActivity anthocyanin 5-aromatic acyltransferase activity Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA. MetaCyc:RXN-7945|RHEA:15661|EC:2.3.1.153 go-plus.json hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity http://purl.obolibrary.org/obo/GO_0047183 GO:0047182 biolink:MolecularActivity alcohol O-cinnamoyltransferase activity Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate. RHEA:23524|MetaCyc:2.3.1.152-RXN|EC:2.3.1.152 go-plus.json 1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity http://purl.obolibrary.org/obo/GO_0047182 GO:0047181 biolink:MolecularActivity tetrahydroxybenzophenone synthase activity Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A. RHEA:19305|MetaCyc:2.3.1.151-RXN|EC:2.3.1.151 go-plus.json malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity http://purl.obolibrary.org/obo/GO_0047181 GO:0047189 biolink:MolecularActivity 2,3-diaminopropionate N-oxalyltransferase activity Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA. EC:2.3.1.58|RHEA:13465|KEGG_REACTION:R04211|MetaCyc:2.3.1.58-RXN go-plus.json oxalyldiaminopropionic synthase activity|oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity|ODAP synthase activity|oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity|oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity|oxalyldiaminopropionate synthase activity http://purl.obolibrary.org/obo/GO_0047189 GO:0047191 biolink:MolecularActivity 1-alkylglycerophosphocholine O-acyltransferase activity Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA. RHEA:23992|MetaCyc:2.3.1.63-RXN|EC:2.3.1.63 go-plus.json acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047191 GO:0072129 biolink:BiologicalProcess renal capsule formation The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. go-plus.json http://purl.obolibrary.org/obo/GO_0072129 GO:0047190 biolink:MolecularActivity 2-acylglycerophosphocholine O-acyltransferase activity Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA. MetaCyc:2.3.1.62-RXN|KEGG_REACTION:R01319|EC:2.3.1.62|RHEA:10332 go-plus.json 2-acylglycerol-3-phosphorylcholine acyltransferase activity|2-acylglycerophosphocholine acyltransferase activity|acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047190 GO:0072128 biolink:BiologicalProcess renal capsule morphogenesis The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. go-plus.json http://purl.obolibrary.org/obo/GO_0072128 GO:0072127 biolink:BiologicalProcess renal capsule development The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. go-plus.json http://purl.obolibrary.org/obo/GO_0072127 GO:0072126 biolink:BiologicalProcess positive regulation of glomerular mesangial cell proliferation Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0072126 GO:0072125 biolink:BiologicalProcess negative regulation of glomerular mesangial cell proliferation Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0072125 GO:0072124 biolink:BiologicalProcess regulation of glomerular mesangial cell proliferation Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0072124 GO:0072123 biolink:BiologicalProcess intraglomerular mesangial cell proliferation The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0072123 GO:0047199 biolink:MolecularActivity phosphatidylcholine-dolichol O-acyltransferase activity Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol. EC:2.3.1.83|RHEA:19285|MetaCyc:2.3.1.83-RXN|KEGG_REACTION:R04227 go-plus.json 3-sn-phosphatidylcholine:dolichol O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047199 GO:0072155 biolink:BiologicalProcess epithelial cell migration involved in nephron tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072155 GO:0072154 biolink:BiologicalProcess proximal convoluted tubule segment 1 cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney. go-plus.json S1 cell fate commitment http://purl.obolibrary.org/obo/GO_0072154 GO:0047198 biolink:MolecularActivity cysteine-S-conjugate N-acetyltransferase activity Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+). KEGG_REACTION:R04950|EC:2.3.1.80|RHEA:19213|Reactome:R-HSA-5433066|MetaCyc:2.3.1.80-RXN go-plus.json acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047198 GO:0047197 biolink:MolecularActivity triglyceride-sterol O-acyltransferase activity Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol. RHEA:16897|MetaCyc:2.3.1.77-RXN|EC:2.3.1.77 go-plus.json triacylglycerol:sterol acyltransferase activity|triacylglycerol:3beta-hydroxysterol O-acyltransferase activity|triacylglycerol-sterol O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047197 GO:0072153 biolink:BiologicalProcess renal interstitial fibroblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast. go-plus.json kidney interstitial cell fate commitment http://purl.obolibrary.org/obo/GO_0072153 GO:0072152 biolink:BiologicalProcess glomerular mesangial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072152 GO:0047196 biolink:MolecularActivity long-chain-alcohol O-fatty-acyltransferase activity Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA. MetaCyc:RXNQT-4193|RHEA:38443|Reactome:R-HSA-8848582|MetaCyc:2.3.1.75-RXN|Reactome:R-HSA-5696424|EC:2.3.1.75 go-plus.json acyl-CoA:long-chain-alcohol O-acyltransferase activity|wax-ester synthase activity|wax synthase activity|wax ester synthase activity http://purl.obolibrary.org/obo/GO_0047196 GO:0072151 biolink:BiologicalProcess mesangial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072151 GO:0047195 biolink:MolecularActivity diacylglycerol-sterol O-acyltransferase activity Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol. RHEA:13301|MetaCyc:2.3.1.73-RXN|EC:2.3.1.73 go-plus.json 1,2-diacyl-sn-glycerol:sterol acyl transferase activity|1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0047195 GO:0047194 biolink:MolecularActivity indoleacetylglucose-inositol O-acyltransferase activity Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose. KEGG_REACTION:R04333|RHEA:21180|MetaCyc:2.3.1.72-RXN|EC:2.3.1.72 go-plus.json indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity|1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity|1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047194 GO:0072150 biolink:BiologicalProcess juxtaglomerulus cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072150 GO:0047193 biolink:MolecularActivity obsolete CDP-acylglycerol O-arachidonoyltransferase activity OBSOLETE. Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA. MetaCyc:2.3.1.70-RXN go-plus.json arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase activity|CDP-acylglycerol O-arachidonyltransferase activity|arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase activity|CDPacylglycerol O-arachidonyltransferase activity|CDP-acylglycerol O-arachidonoyltransferase activity http://purl.obolibrary.org/obo/GO_0047193 GO:0047192 biolink:MolecularActivity 1-alkylglycerophosphocholine O-acetyltransferase activity Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA. MetaCyc:2.3.1.67-RXN|RHEA:18461|EC:2.3.1.67 go-plus.json acetyl-CoA:lyso-PAF acetyltransferase activity|blood platelet-activating factor acetyltransferase activity|lyso-GPC:acetyl CoA acetyltransferase activity|lyso-platelet activating factor:acetyl-CoA acetyltransferase activity|platelet-activating factor-synthesizing enzyme activity|acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity|lysoPAF:acetyl CoA acetyltransferase activity|acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|lysopaf:acetyl CoA acetyltransferase activity|lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity|1-alkyl-2-lysolecithin acetyltransferase activity|1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity|platelet-activating factor acylhydrolase activity http://purl.obolibrary.org/obo/GO_0047192 GO:0072159 biolink:BiologicalProcess epithelial cell migration involved in proximal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072159 GO:0072158 biolink:BiologicalProcess proximal tubule morphogenesis The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0072158 GO:0072157 biolink:BiologicalProcess epithelial cell migration involved in distal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072157 GO:0072156 biolink:BiologicalProcess distal tubule morphogenesis The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072156 GO:0072144 biolink:BiologicalProcess glomerular mesangial cell development The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072144 GO:0072143 biolink:BiologicalProcess mesangial cell development The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072143 GO:0072142 biolink:BiologicalProcess juxtaglomerulus cell development The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072142 GO:0072141 biolink:BiologicalProcess renal interstitial fibroblast development The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure. go-plus.json kidney interstitial cell development http://purl.obolibrary.org/obo/GO_0072141 GO:0072140 biolink:BiologicalProcess DCT cell development The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure. go-plus.json distal convoluted tubule cell development http://purl.obolibrary.org/obo/GO_0072140 GO:0072149 biolink:BiologicalProcess glomerular visceral epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. go-plus.json podocyte cell fate commitment http://purl.obolibrary.org/obo/GO_0072149 GO:0072148 biolink:BiologicalProcess epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072148 GO:0072147 biolink:BiologicalProcess glomerular parietal epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. go-plus.json Bowman's capsule cell fate commitment http://purl.obolibrary.org/obo/GO_0072147 GO:0072146 biolink:BiologicalProcess DCT cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell. go-plus.json distal convoluted tubule cell fate commitment http://purl.obolibrary.org/obo/GO_0072146 GO:0072145 biolink:BiologicalProcess proximal convoluted tubule segment 1 cell development The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure. go-plus.json S1 cell development http://purl.obolibrary.org/obo/GO_0072145 CL:0002265 biolink:Cell type D cell of colon A D cell located in the colon. go-plus.json colonic delta cell|colon D-cell|delta cell of colon http://purl.obolibrary.org/obo/CL_0002265 CL:0002264 biolink:Cell type A cell of stomach A type of enteroendocrine cell found in the stomach that secretes glucagon. go-plus.json http://purl.obolibrary.org/obo/CL_0002264 CL:0002267 biolink:Cell type D cell of stomach A type D cell found in the stomach. go-plus.json stomach D-cell|stomach delta cell|delta cell of stomach http://purl.obolibrary.org/obo/CL_0002267 CL:0002266 biolink:Cell type D cell of small intestine A type D cell of the small intestine. go-plus.json delta cell of small intestine|small intestine D-cell|small intestine delta cell http://purl.obolibrary.org/obo/CL_0002266 CHEBI:74463 biolink:ChemicalSubstance lysophosphatidylinositol 16:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74463 chebi_ph7_3 CL:0002260 biolink:Cell epithelial cell of parathyroid gland An epithelial cell of the parathyroid gland. go-plus.json http://purl.obolibrary.org/obo/CL_0002260 CHEBI:74466 biolink:ChemicalSubstance lysophosphatidylinositol 18:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74466 chebi_ph7_3 CHEBI:74465 biolink:ChemicalSubstance lysophosphatidylinositol 18:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74465 chebi_ph7_3 CHEBI:25501 biolink:ChemicalSubstance neoxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25501 CHEBI:74478 biolink:ChemicalSubstance 2'-O-methyluridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74478 chebi_ph7_3 CHEBI:25500 biolink:ChemicalSubstance neopterins go-plus.json http://purl.obolibrary.org/obo/CHEBI_25500 CHEBI:25505 biolink:ChemicalSubstance neuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25505 CL:0002275 biolink:Cell pancreatic PP cell A PP cell located in the islets of the pancreas. go-plus.json pancreatic polypeptide-secreting cell|PP-cell of pancreatic islet|PP cell of pancreatic islet http://purl.obolibrary.org/obo/CL_0002275 CHEBI:25508 biolink:ChemicalSubstance neuraminic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_25508 CHEBI:25506 biolink:ChemicalSubstance neuraminates go-plus.json http://purl.obolibrary.org/obo/CHEBI_25506 CHEBI:74474 biolink:ChemicalSubstance (R)-3-hydroxyhexanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74474 CHEBI:74477 biolink:ChemicalSubstance 2'-O-methyladenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74477 chebi_ph7_3 CL:0002274 biolink:Cell histamine secreting cell A cell type that secretes histamine. go-plus.json http://purl.obolibrary.org/obo/CL_0002274 CHEBI:74476 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74476 CHEBI:74489 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74489 CL:0002242 biolink:Cell nucleate cell A cell containing at least one nucleus. go-plus.json http://purl.obolibrary.org/obo/CL_0002242 CHEBI:74480 biolink:ChemicalSubstance N(7)-methylguanosine 5'-phosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74480 chebi_ph7_3 CHEBI:74481 biolink:ChemicalSubstance N(2)-methylguanosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74481 chebi_ph7_3 CHEBI:74483 biolink:ChemicalSubstance 5-methylcytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74483 chebi_ph7_3 CHEBI:74486 biolink:ChemicalSubstance N(3)-methylpseudouridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74486 chebi_ph7_3 CHEBI:74485 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74485 CL:0002240 biolink:Cell marrow fibroblast A fibroblast in the bone marrow. go-plus.json http://purl.obolibrary.org/obo/CL_0002240 GO:1904909 biolink:BiologicalProcess positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. go-plus.json up regulation of maintenance of sister chromatin cohesion at telomere at mitosis|activation of maintenance of sister chromatin cohesion at telomere at mitosis|positive regulation of maintenance of mitotic sister chromatin cohesion at telomere|positive regulation of maintenance of sister chromatin cohesion at telomere at mitosis|up regulation of maintenance of mitotic sister chromatid cohesion, telomeric|up-regulation of maintenance of telomeric mitotic sister chromatin cohesion|activation of maintenance of telomeric mitotic sister chromatin cohesion|activation of maintenance of mitotic sister chromatid cohesion, telomeric|up regulation of maintenance of mitotic sister chromatin cohesion at telomere|up-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|upregulation of maintenance of mitotic sister chromatin cohesion at telomere|positive regulation of maintenance of telomeric mitotic sister chromatin cohesion|up-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|up regulation of maintenance of telomeric mitotic sister chromatin cohesion|upregulation of maintenance of sister chromatin cohesion at telomere at mitosis|activation of maintenance of mitotic sister chromatin cohesion at telomere|up-regulation of maintenance of mitotic sister chromatin cohesion at telomere|upregulation of maintenance of mitotic sister chromatid cohesion, telomeric|upregulation of maintenance of telomeric mitotic sister chromatin cohesion http://purl.obolibrary.org/obo/GO_1904909 GO:1904908 biolink:BiologicalProcess negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. go-plus.json downregulation of maintenance of sister chromatin cohesion at telomere at mitosis|down-regulation of maintenance of mitotic sister chromatin cohesion at telomere|negative regulation of maintenance of mitotic sister chromatin cohesion at telomere|downregulation of maintenance of mitotic sister chromatid cohesion, telomeric|down-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|negative regulation of maintenance of sister chromatin cohesion at telomere at mitosis|downregulation of maintenance of mitotic sister chromatin cohesion at telomere|down-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|negative regulation of maintenance of telomeric mitotic sister chromatin cohesion|down-regulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of mitotic sister chromatin cohesion at telomere|inhibition of maintenance of sister chromatin cohesion at telomere at mitosis|inhibition of maintenance of mitotic sister chromatin cohesion at telomere|inhibition of maintenance of mitotic sister chromatid cohesion, telomeric|downregulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of sister chromatin cohesion at telomere at mitosis|inhibition of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of mitotic sister chromatid cohesion, telomeric http://purl.obolibrary.org/obo/GO_1904908 GO:1904907 biolink:BiologicalProcess regulation of maintenance of mitotic sister chromatid cohesion, telomeric Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. go-plus.json regulation of maintenance of mitotic sister chromatin cohesion at telomere|regulation of maintenance of telomeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at telomere at mitosis http://purl.obolibrary.org/obo/GO_1904907 GO:1904906 biolink:BiologicalProcess positive regulation of endothelial cell-matrix adhesion via fibronectin Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin. go-plus.json up regulation of endothelial cell-matrix adhesion via fibronectin|upregulation of endothelial cell-matrix adhesion via fibronectin|up-regulation of endothelial cell-matrix adhesion via fibronectin|activation of endothelial cell-matrix adhesion via fibronectin http://purl.obolibrary.org/obo/GO_1904906 GO:1904905 biolink:BiologicalProcess negative regulation of endothelial cell-matrix adhesion via fibronectin Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin. go-plus.json down-regulation of endothelial cell-matrix adhesion via fibronectin|downregulation of endothelial cell-matrix adhesion via fibronectin|down regulation of endothelial cell-matrix adhesion via fibronectin|inhibition of endothelial cell-matrix adhesion via fibronectin http://purl.obolibrary.org/obo/GO_1904905 GO:1904904 biolink:BiologicalProcess regulation of endothelial cell-matrix adhesion via fibronectin Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin. go-plus.json http://purl.obolibrary.org/obo/GO_1904904 GO:1904903 biolink:BiologicalProcess ESCRT III complex disassembly The disaggregation of an ESCRT III complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_1904903 GO:1904902 biolink:BiologicalProcess ESCRT III complex assembly The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex. go-plus.json ESCRT III complex formation http://purl.obolibrary.org/obo/GO_1904902 GO:1904901 biolink:BiologicalProcess positive regulation of myosin II filament organization Any process that activates or increases the frequency, rate or extent of myosin II filament organization. go-plus.json upregulation of myosin II filament organization|activation of myosin II polymerization or depolymerization|up regulation of myosin II filament organisation|activation of myosin II filament assembly or disassembly|activation of myosin II filament organisation|positive regulation of myosin II filament organisation|positive regulation of myosin II polymerization or depolymerization|up regulation of myosin II polymerization or depolymerization|positive regulation of myosin II filament assembly or disassembly|up regulation of myosin II filament organization|up regulation of myosin II filament assembly or disassembly|activation of myosin II filament organization|up-regulation of myosin II filament organisation|upregulation of myosin II polymerization or depolymerization|upregulation of myosin II filament assembly or disassembly|up-regulation of myosin II filament organization|upregulation of myosin II filament organisation|up-regulation of myosin II polymerization or depolymerization|up-regulation of myosin II filament assembly or disassembly http://purl.obolibrary.org/obo/GO_1904901 GO:1904900 biolink:BiologicalProcess negative regulation of myosin II filament organization Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization. go-plus.json downregulation of myosin II filament organisation|down-regulation of myosin II polymerization or depolymerization|negative regulation of myosin II polymerization or depolymerization|down regulation of myosin II filament organization|down-regulation of myosin II filament assembly or disassembly|negative regulation of myosin II filament assembly or disassembly|downregulation of myosin II filament organization|negative regulation of myosin II filament organisation|down-regulation of myosin II filament organisation|downregulation of myosin II polymerization or depolymerization|downregulation of myosin II filament assembly or disassembly|down regulation of myosin II polymerization or depolymerization|inhibition of myosin II filament organisation|down-regulation of myosin II filament organization|down regulation of myosin II filament assembly or disassembly|inhibition of myosin II polymerization or depolymerization|inhibition of myosin II filament organization|inhibition of myosin II filament assembly or disassembly|down regulation of myosin II filament organisation http://purl.obolibrary.org/obo/GO_1904900 CL:0002254 biolink:Cell epithelial cell of small intestine An epithelial cell of the small intestine. go-plus.json http://purl.obolibrary.org/obo/CL_0002254 CL:0002253 biolink:Cell epithelial cell of large intestine An epithelial cell of the large intestine. go-plus.json epithelial cell of colon http://purl.obolibrary.org/obo/CL_0002253 CL:0002257 biolink:Cell epithelial cell of thyroid gland An epithelial cell of thyroid gland. go-plus.json http://purl.obolibrary.org/obo/CL_0002257 CHEBI:74491 biolink:ChemicalSubstance N(1)-methyladenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74491 chebi_ph7_3 CHEBI:74493 biolink:ChemicalSubstance N(6),N(6)-dimethyladenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74493 chebi_ph7_3 PR:000012421 biolink:Protein proliferating cell nuclear antigen A protein that is a translation product of the human PCNA gene or a 1:1 ortholog thereof. go-plus.json PCNA|cyclin http://purl.obolibrary.org/obo/PR_000012421 CHEBI:74495 biolink:ChemicalSubstance 2'-O-methylcytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74495 chebi_ph7_3 CHEBI:74497 biolink:ChemicalSubstance 2-methyladenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74497 chebi_ph7_3 CHEBI:74496 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z)-3-oxotriacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74496 CL:0002252 biolink:Cell epithelial cell of esophagus An epithelial cell of the esophagus. go-plus.json http://purl.obolibrary.org/obo/CL_0002252 CHEBI:74499 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74499 CL:0002251 biolink:Cell epithelial cell of alimentary canal An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. go-plus.json http://purl.obolibrary.org/obo/CL_0002251 GO:1904919 biolink:BiologicalProcess transmembrane L-cystine transport from lysosomal lumen to cytosol The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1904919 GO:1904918 biolink:BiologicalProcess transmembrane L-histidine transport from lysosomal lumen to cytosol The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1904918 GO:1904917 biolink:BiologicalProcess L-arginine transmembrane transport from lysosomal lumen to cytosol The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol. go-plus.json transmembrane L-arginine transport from lysosomal lumen to cytosol http://purl.obolibrary.org/obo/GO_1904917 GO:1904916 biolink:BiologicalProcess transmembrane L-lysine transport from lysosomal lumen to cytosol The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1904916 GO:1904915 biolink:BiologicalProcess positive regulation of establishment of protein-containing complex localization to telomere Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. go-plus.json positive regulation of establishment of macromolecular complex localisation to telomere|up regulation of establishment of macromolecular complex localisation to telomere|up regulation of establishment of macromolecular complex localization to telomere|upregulation of establishment of macromolecular complex localisation to telomere|upregulation of establishment of macromolecular complex localization to telomere|up-regulation of establishment of macromolecular complex localisation to telomere|activation of establishment of macromolecular complex localisation to telomere|up-regulation of establishment of macromolecular complex localization to telomere|activation of establishment of macromolecular complex localization to telomere|positive regulation of establishment of macromolecular complex localization to telomere http://purl.obolibrary.org/obo/GO_1904915 GO:1904914 biolink:BiologicalProcess negative regulation of establishment of protein-containing complex localization to telomere Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. go-plus.json down-regulation of establishment of macromolecular complex localization to telomere|downregulation of establishment of macromolecular complex localisation to telomere|down regulation of establishment of macromolecular complex localisation to telomere|inhibition of establishment of macromolecular complex localisation to telomere|downregulation of establishment of macromolecular complex localization to telomere|down regulation of establishment of macromolecular complex localization to telomere|inhibition of establishment of macromolecular complex localization to telomere|negative regulation of establishment of macromolecular complex localization to telomere|negative regulation of establishment of macromolecular complex localisation to telomere|down-regulation of establishment of macromolecular complex localisation to telomere http://purl.obolibrary.org/obo/GO_1904914 GO:1904913 biolink:BiologicalProcess regulation of establishment of protein-containing complex localization to telomere Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. go-plus.json regulation of establishment of macromolecular complex localization to telomere|regulation of establishment of macromolecular complex localisation to telomere http://purl.obolibrary.org/obo/GO_1904913 GO:1904912 biolink:BiologicalProcess positive regulation of establishment of RNA localization to telomere Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere. go-plus.json upregulation of establishment of RNA localization to telomere|up regulation of establishment of RNA localisation to telomere|activation of establishment of RNA localisation to telomere|positive regulation of establishment of RNA localisation to telomere|up regulation of establishment of RNA localization to telomere|activation of establishment of RNA localization to telomere|up-regulation of establishment of RNA localisation to telomere|up-regulation of establishment of RNA localization to telomere|upregulation of establishment of RNA localisation to telomere http://purl.obolibrary.org/obo/GO_1904912 GO:1904911 biolink:BiologicalProcess negative regulation of establishment of RNA localization to telomere Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere. go-plus.json down regulation of establishment of RNA localization to telomere|downregulation of establishment of RNA localization to telomere|down-regulation of establishment of RNA localisation to telomere|negative regulation of establishment of RNA localisation to telomere|down-regulation of establishment of RNA localization to telomere|inhibition of establishment of RNA localisation to telomere|inhibition of establishment of RNA localization to telomere|down regulation of establishment of RNA localisation to telomere|downregulation of establishment of RNA localisation to telomere http://purl.obolibrary.org/obo/GO_1904911 GO:1904910 biolink:BiologicalProcess regulation of establishment of RNA localization to telomere Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere. go-plus.json regulation of establishment of RNA localisation to telomere http://purl.obolibrary.org/obo/GO_1904910 CL:1000497 biolink:Cell kidney cell go-plus.json http://purl.obolibrary.org/obo/CL_1000497 CL:0002222 biolink:Cell vertebrate lens cell A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. go-plus.json http://purl.obolibrary.org/obo/CL_0002222 CL:1000495 biolink:Cell small intestine goblet cell A goblet cell that is part of the small intestine. go-plus.json small intestinal goblet cell|goblet cell of epithelium of small intestine|goblet cell of small intestine http://purl.obolibrary.org/obo/CL_1000495 CL:1000494 biolink:Cell nephron tubule epithelial cell An epithelial cell that is part of a nephron tubule. go-plus.json kidney tubule epithelial cell http://purl.obolibrary.org/obo/CL_1000494 CL:1000490 biolink:Cell mesothelial cell of peritoneum A mesothelial cell that is part of the peritoneum. go-plus.json peritoneal mesothelial cell http://purl.obolibrary.org/obo/CL_1000490 GO:0047100 biolink:MolecularActivity glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate. RHEA:10296|MetaCyc:1.2.1.13-RXN|EC:1.2.1.13 go-plus.json triosephosphate dehydrogenase (NADP+) activity|triosephosphate dehydrogenase (NADP(+)) activity|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|triosephosphate dehydrogenase (NADP)|NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity|NADP-triose phosphate dehydrogenase activity|NADP-dependent glyceraldehyde phosphate dehydrogenase activity|glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating) http://purl.obolibrary.org/obo/GO_0047100 NCBITaxon:3931 biolink:OrganismalEntity Myrtaceae go-plus.json myrtle family http://purl.obolibrary.org/obo/NCBITaxon_3931 GO:1904929 biolink:MolecularActivity coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway. go-plus.json coreceptor activity involved in Wnt-JNK signaling pathway|coreceptor, insoluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in planar cell polarity pathway|Wnt co-receptor activity, non-canonical signaling|coreceptor, insoluble ligand activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway|coreceptor activity involved in non-canonical Wnt signaling pathway|coreceptor activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in planar cell polarity pathway|coreceptor activity involved in Wnt-PCP signaling pathway|coreceptor, soluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor activity involved in planar cell polarity pathway|coreceptor activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in Wnt-PCP signaling pathway|coreceptor, insoluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|Wnt co-receptor, non-canonical pathway|coreceptor, insoluble ligand activity involved in Wnt-PCP signaling pathway|Wnt/PCP co-receptor activity|coreceptor, soluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in PCP pathway|coreceptor, soluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway http://purl.obolibrary.org/obo/GO_1904929 GO:1904928 biolink:MolecularActivity coreceptor activity involved in canonical Wnt signaling pathway Any coreceptor activity that is involved in a canonical Wnt signaling pathway. go-plus.json coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor activity involved in frizzled-1 receptor signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt-activated signaling pathway|Wnt co-receptor, canonical pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt-activated signaling pathway|coreceptor activity involved in canonical Wnt receptor signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, insoluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway through beta-catenin|Wnt co-receptor activity, canonical signaling|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, insoluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor activity involved in canonical Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_1904928 NCBITaxon:3932 biolink:OrganismalEntity Eucalyptus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3932 GO:1904927 biolink:BiologicalProcess cellular response to palmitoleic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904927 GO:1904926 biolink:BiologicalProcess response to palmitoleic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904926 GO:1904925 biolink:BiologicalProcess positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization. go-plus.json upregulation of mitophagy in response to mitochondrial depolarization|up regulation of mitophagy in response to mitochondrial depolarization|activation of mitophagy in response to mitochondrial depolarization|up-regulation of mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1904925 GO:1904924 biolink:BiologicalProcess negative regulation of mitophagy in response to mitochondrial depolarization Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization. go-plus.json down regulation of mitophagy in response to mitochondrial depolarization|downregulation of mitophagy in response to mitochondrial depolarization|down-regulation of mitophagy in response to mitochondrial depolarization|inhibition of mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_1904924 GO:0047108 biolink:MolecularActivity (R)-3-hydroxyacid-ester dehydrogenase activity Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH. KEGG_REACTION:R04105|RHEA:24352|MetaCyc:1.2.1.55-RXN|EC:1.1.1.279 go-plus.json 3-oxo ester (R)-reductase activity|(R)-3-hydroxyacid ester dehydrogenase activity|ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047108 GO:1904923 biolink:BiologicalProcess regulation of autophagy of mitochondrion in response to mitochondrial depolarization Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization. go-plus.json http://purl.obolibrary.org/obo/GO_1904923 GO:1904922 biolink:BiologicalProcess obsolete positive regulation of MAPK cascade involved in axon regeneration OBSOLETE. Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in axon regeneration. go-plus.json upregulation of mitogen-activated protein kinase cascade involved in axon regeneration|up-regulation of MAPK signalling involved in axon regeneration|activation of MAPKKK cascade during sporulation involved in axon regeneration|activation of MAPK signaling involved in axon regeneration|activation of MAP kinase cascade involved in axon regeneration|activation of MAP kinase kinase kinase cascade involved in axon regeneration|up-regulation of MAP kinase cascade involved in axon regeneration|up-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|positive regulation of MAPK signal transduction involved in axon regeneration|up-regulation of ERK/MAPK cascade involved in axon regeneration|positive regulation of MAPK signaling involved in axon regeneration|up-regulation of MAPKKK cascade during sporulation involved in axon regeneration|up regulation of MAPK signal transduction involved in axon regeneration|positive regulation of MAPKKK cascade involved in axon regeneration|up regulation of MAPK signaling involved in axon regeneration|activation of mitogen-activated protein kinase cascade involved in axon regeneration|up-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|upregulation of MAPK signalling involved in axon regeneration|up regulation of MAPK cascade involved in axon regeneration|up regulation of MAPKKK cascade involved in axon regeneration|activation of ERK/MAPK cascade involved in axon regeneration|positive regulation of MAP kinase cascade involved in axon regeneration|positive regulation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPKKK cascade during sporulation involved in axon regeneration|positive regulation of ERK/MAPK cascade involved in axon regeneration|up regulation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPK signal transduction involved in axon regeneration|up regulation of MAP kinase cascade involved in axon regeneration|up regulation of ERK/MAPK cascade involved in axon regeneration|up regulation of MAPK signalling involved in axon regeneration|upregulation of MAPK signaling involved in axon regeneration|upregulation of MAPKKK cascade involved in axon regeneration|positive regulation of mitogen-activated protein kinase cascade involved in axon regeneration|upregulation of MAPK cascade involved in axon regeneration|positive regulation of MAPK signalling involved in axon regeneration|up regulation of mitogen-activated protein kinase cascade involved in axon regeneration|activation of MAPK signalling involved in axon regeneration|up-regulation of MAPK signal transduction involved in axon regeneration|up regulation of MAPKKK cascade during sporulation involved in axon regeneration|activation of MAPK signal transduction involved in axon regeneration|upregulation of MAP kinase cascade involved in axon regeneration|upregulation of MAP kinase kinase kinase cascade involved in axon regeneration|up-regulation of MAPK signaling involved in axon regeneration|positive regulation of MAPKKK cascade during sporulation involved in axon regeneration|up-regulation of MAPKKK cascade involved in axon regeneration|upregulation of ERK/MAPK cascade involved in axon regeneration|up-regulation of MAPK cascade involved in axon regeneration|activation of MAPK cascade involved in axon regeneration|activation of MAPKKK cascade involved in axon regeneration http://purl.obolibrary.org/obo/GO_1904922 GO:0047107 biolink:MolecularActivity gamma-guanidinobutyraldehyde dehydrogenase activity Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH. KEGG_REACTION:R03177|MetaCyc:1.2.1.54-RXN|RHEA:14381|EC:1.2.1.54 go-plus.json alpha-guanidinobutyraldehyde dehydrogenase activity|4-guanidinobutyraldehyde dehydrogenase activity|GBAL dehydrogenase activity|4-guanidinobutanal:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047107 GO:0047106 biolink:MolecularActivity 4-hydroxyphenylacetaldehyde dehydrogenase activity Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate. MetaCyc:1.2.1.53-RXN|RHEA:17273|EC:1.2.1.53 go-plus.json 4-HPAL dehydrogenase activity|4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047106 GO:1904921 biolink:BiologicalProcess obsolete negative regulation of MAPK cascade involved in axon regeneration OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in axon regeneration. go-plus.json down-regulation of MAPKKK cascade during sporulation involved in axon regeneration|down-regulation of MAPK signal transduction involved in axon regeneration|negative regulation of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signal transduction involved in axon regeneration|inhibition of ERK/MAPK cascade involved in axon regeneration|negative regulation of MAPK signaling involved in axon regeneration|down-regulation of MAPK signaling involved in axon regeneration|down-regulation of MAPK cascade involved in axon regeneration|negative regulation of MAPKKK cascade involved in axon regeneration|down-regulation of MAPKKK cascade involved in axon regeneration|inhibition of MAPK signalling involved in axon regeneration|downregulation of MAPK signal transduction involved in axon regeneration|negative regulation of MAP kinase cascade involved in axon regeneration|negative regulation of MAP kinase kinase kinase cascade involved in axon regeneration|downregulation of MAPK signaling involved in axon regeneration|down-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|down regulation of MAPK signalling involved in axon regeneration|down-regulation of MAP kinase cascade involved in axon regeneration|downregulation of MAPKKK cascade involved in axon regeneration|downregulation of MAPK cascade involved in axon regeneration|inhibition of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of ERK/MAPK cascade involved in axon regeneration|down-regulation of ERK/MAPK cascade involved in axon regeneration|down regulation of MAPK signal transduction involved in axon regeneration|downregulation of MAPK signalling involved in axon regeneration|down regulation of MAPK signaling involved in axon regeneration|negative regulation of mitogen-activated protein kinase cascade involved in axon regeneration|down-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|down regulation of MAPK cascade involved in axon regeneration|inhibition of MAPK signal transduction involved in axon regeneration|down regulation of MAPKKK cascade involved in axon regeneration|inhibition of MAPK cascade involved in axon regeneration|inhibition of MAPKKK cascade involved in axon regeneration|downregulation of MAP kinase kinase kinase cascade involved in axon regeneration|downregulation of MAP kinase cascade involved in axon regeneration|down regulation of MAPKKK cascade during sporulation involved in axon regeneration|inhibition of MAPK signaling involved in axon regeneration|downregulation of ERK/MAPK cascade involved in axon regeneration|downregulation of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signalling involved in axon regeneration|down regulation of MAP kinase kinase kinase cascade involved in axon regeneration|down-regulation of MAPK signalling involved in axon regeneration|down regulation of MAP kinase cascade involved in axon regeneration|downregulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of MAP kinase cascade involved in axon regeneration|down regulation of ERK/MAPK cascade involved in axon regeneration|inhibition of MAP kinase kinase kinase cascade involved in axon regeneration|down regulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of mitogen-activated protein kinase cascade involved in axon regeneration http://purl.obolibrary.org/obo/GO_1904921 GO:1904920 biolink:BiologicalProcess obsolete regulation of MAPK cascade involved in axon regeneration OBSOLETE. Any process that modulates the frequency, rate or extent of MAPK cascade involved in axon regeneration. go-plus.json regulation of MAPK signal transduction involved in axon regeneration|regulation of MAPK signalling involved in axon regeneration|regulation of MAPK signaling involved in axon regeneration|regulation of MAPKKK cascade involved in axon regeneration|regulation of MAPKKK cascade during sporulation involved in axon regeneration|regulation of MAP kinase kinase kinase cascade involved in axon regeneration|regulation of MAP kinase cascade involved in axon regeneration|regulation of ERK/MAPK cascade involved in axon regeneration|regulation of mitogen-activated protein kinase cascade involved in axon regeneration http://purl.obolibrary.org/obo/GO_1904920 GO:0047105 biolink:MolecularActivity 4-trimethylammoniobutyraldehyde dehydrogenase activity Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate. RHEA:17985|MetaCyc:1.2.1.47-RXN|EC:1.2.1.47 go-plus.json 4-trimethylaminobutyraldehyde dehydrogenase activity|4-N-trimethylaminobutyraldehyde dehydrogenase activity|4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047105 GO:0047104 biolink:MolecularActivity hexadecanal dehydrogenase (acylating) activity Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA. KEGG_REACTION:R01277|UM-BBD_reactionID:r1374|MetaCyc:1.2.1.42-RXN|EC:1.2.1.42|RHEA:19705 go-plus.json fatty acyl-CoA reductase activity|hexadecanal:NAD+ oxidoreductase (CoA-acylating) http://purl.obolibrary.org/obo/GO_0047104 GO:0047103 biolink:MolecularActivity 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate. RHEA:24584|MetaCyc:1.2.1.40-RXN go-plus.json trihydroxydeoxycoprostanal dehydrogenase activity|3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity|cholestanetriol-26-al 26-dehydrogenase activity|THAL-NAD oxidoreductase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047103 GO:0047102 biolink:MolecularActivity aminomuconate-semialdehyde dehydrogenase activity Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate. MetaCyc:1.2.1.32-RXN|Reactome:R-HSA-71239|EC:1.2.1.32|UM-BBD_reactionID:r1434|RHEA:14469 go-plus.json 2-hydroxymuconic acid semialdehyde dehydrogenase activity|2-hydroxymuconic semialdehyde dehydrogenase activity|2-aminomuconate semialdehyde dehydrogenase activity|2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity|alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity|2-hydroxymuconate semialdehyde dehydrogenase activity|alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047102 GO:0047101 biolink:MolecularActivity 2-oxoisovalerate dehydrogenase (acylating) activity Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA. MetaCyc:1.2.1.25-RXN|EC:1.2.1.25|RHEA:13997 go-plus.json 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)|2-oxoisovalerate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047101 CL:1000488 biolink:Cell cholangiocyte An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. go-plus.json epithelial cell of bile duct http://purl.obolibrary.org/obo/CL_1000488 CL:0002231 biolink:Cell epithelial cell of prostate An epithelial cell of the prostate. go-plus.json prostate epithelial cell http://purl.obolibrary.org/obo/CL_0002231 CL:1000487 biolink:Cell smooth muscle cell of prostate A smooth muscle cell that is part of the prostate gland. go-plus.json smooth muscle fiber of prostate http://purl.obolibrary.org/obo/CL_1000487 CL:0002234 biolink:Cell basal cell of prostatic acinus A cell of the basal layer of the epithelium in the prostatic acinus. go-plus.json basal epithelial cell of prostatic acinus http://purl.obolibrary.org/obo/CL_0002234 CL:1000486 biolink:Cell basal cell of urothelium A basal cell that is part of the urothelium. go-plus.json http://purl.obolibrary.org/obo/CL_1000486 CL:0002233 biolink:Cell epithelial cell of prostatic acinus An epithelial cell of the prostatic acinus. go-plus.json acinar epithelial cell of prostate http://purl.obolibrary.org/obo/CL_0002233 CL:1000484 biolink:Cell Purkinje myocyte of atrioventricular bundle A Purkinje myocyte that is part of the atrioventricular bundle. go-plus.json http://purl.obolibrary.org/obo/CL_1000484 GO:0047109 biolink:MolecularActivity (S)-3-hydroxyacid-ester dehydrogenase activity Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH. KEGG_REACTION:R04106|RHEA:18269|MetaCyc:1.2.1.56-RXN|EC:1.1.1.280 go-plus.json ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity|(S)-3-hydroxyacid ester dehydrogenase activity|3-oxo ester (S)-reductase activity http://purl.obolibrary.org/obo/GO_0047109 SO:0001797 biolink:SequenceFeature centromeric_repeat A repeat region found within the modular centromere. go-plus.json INSDC_feature:repeat_region|INSDC_qualifier:centromeric_repeat|centromeric repeat http://purl.obolibrary.org/obo/SO_0001797 SO:0001796 biolink:SequenceFeature regional_centromere_central_core A conserved region within the central region of a modular centromere, where the kinetochore is formed. go-plus.json regional centromere central core http://purl.obolibrary.org/obo/SO_0001796 SO:0001799 biolink:SequenceFeature regional_centromere_outer_repeat_region The heterochromatic outer repeat region of a modular centromere. These repeats exist in tandem arrays on both chromosome arms. go-plus.json regional centromere outer repeat region http://purl.obolibrary.org/obo/SO_0001799 SO:0001798 biolink:SequenceFeature regional_centromere_inner_repeat_region The inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm. go-plus.json regional centromere inner repeat region|lmr1R|lmr1L|lmr repeat http://purl.obolibrary.org/obo/SO_0001798 GO:0047111 biolink:MolecularActivity formate dehydrogenase (cytochrome-c-553) activity Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2. EC:1.17.2.3|MetaCyc:1.2.2.3-RXN|RHEA:15189 go-plus.json formate dehydrogenase (cytochrome c-553)|formate:ferricytochrome-c-553 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047111 GO:0047110 biolink:MolecularActivity phenylglyoxylate dehydrogenase (acylating) activity Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH. EC:1.2.1.58|KEGG_REACTION:R02450|RHEA:10372|MetaCyc:1.2.1.58-RXN go-plus.json phenylglyoxylate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047110 GO:1904939 biolink:BiologicalProcess regulation of DNA nucleotidylexotransferase activity Any process that modulates the frequency, rate or extent of DNA nucleotidylexotransferase activity. go-plus.json regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|regulation of deoxyribonucleic nucleotidyltransferase activity|regulation of deoxyribonucleic acid nucleotidyltransferase activity|regulation of terminal deoxynucleotide transferase activity|regulation of terminal transferase activity|regulation of deoxynucleotidyl terminal transferase activity|regulation of terminal addition enzyme activity|regulation of terminal deoxynucleotidyltransferase activity|regulation of terminal deoxyribonucleotidyltransferase activity|regulation of TdT|regulation of addase activity http://purl.obolibrary.org/obo/GO_1904939 GO:1904938 biolink:BiologicalProcess planar cell polarity pathway involved in axon guidance Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance. go-plus.json Wnt receptor signaling pathway, planar cell polarity pathway involved in axon guidance|planar cell polarity pathway involved in axon chemotaxis|PCP pathway involved in axon guidance|Wnt-PCP signaling pathway involved in axon chemotaxis|Wnt-PCP signaling pathway involved in axon pathfinding|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon guidance|Wnt-PCP signaling involved in axon guidance|non-canonical Wnt signaling pathway involved in axon pathfinding|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon chemotaxis|PCP pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt-JNK signaling pathway involved in axon pathfinding|planar cell polarity pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon growth cone guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt signaling pathway, planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon pathfinding|non-canonical Wnt signaling pathway involved in axon growth cone guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon pathfinding|planar cell polarity pathway involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt-PCP signaling pathway involved in axon growth cone guidance|non-canonical Wnt signaling pathway involved in axon guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt-PCP signaling pathway involved in axon guidance|non-canonical Wnt signaling pathway involved in axon chemotaxis|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon guidance|planar cell polarity pathway involved in axon pathfinding http://purl.obolibrary.org/obo/GO_1904938 GO:1904937 biolink:BiologicalProcess sensory neuron migration The orderly movement of a sensory neuron from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_1904937 GO:1904936 biolink:BiologicalProcess interneuron migration The orderly movement of an interneuron from one site to another. go-plus.json inter neuron migration|inter-neuron migration http://purl.obolibrary.org/obo/GO_1904936 GO:1904935 biolink:BiologicalProcess positive regulation of cell proliferation in midbrain Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. go-plus.json up regulation of cell proliferation in mesencephalon|positive regulation of cell proliferation in mesencephalon|upregulation of mesencepahalic cell proliferation|upregulation of cell proliferation in midbrain|activation of cell proliferation in mesencephalon|up-regulation of cell proliferation in midbrain|activation of cell proliferation in midbrain|up regulation of mesencepahalic cell proliferation|up-regulation of cell proliferation in mesencephalon|positive regulation of mesencepahalic cell proliferation|activation of mesencepahalic cell proliferation|upregulation of cell proliferation in mesencephalon|up regulation of cell proliferation in midbrain|up-regulation of mesencepahalic cell proliferation http://purl.obolibrary.org/obo/GO_1904935 GO:1904934 biolink:BiologicalProcess negative regulation of cell proliferation in midbrain Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. go-plus.json inhibition of cell proliferation in midbrain|down regulation of mesencepahalic cell proliferation|negative regulation of cell proliferation in mesencephalon|down-regulation of cell proliferation in mesencephalon|downregulation of mesencepahalic cell proliferation|inhibition of cell proliferation in mesencephalon|down-regulation of mesencepahalic cell proliferation|down-regulation of cell proliferation in midbrain|negative regulation of mesencepahalic cell proliferation|down regulation of cell proliferation in mesencephalon|downregulation of cell proliferation in midbrain|downregulation of cell proliferation in mesencephalon|inhibition of mesencepahalic cell proliferation|down regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_1904934 GO:0047119 biolink:MolecularActivity 2-methyl-branched-chain-enoyl-CoA reductase activity Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH. EC:1.3.1.52|KEGG_REACTION:R03169|RHEA:24532|MetaCyc:1.3.1.52-RXN go-plus.json 2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047119 GO:1904933 biolink:BiologicalProcess regulation of cell proliferation in midbrain Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. go-plus.json regulation of mesencepahalic cell proliferation|regulation of cell proliferation in mesencephalon http://purl.obolibrary.org/obo/GO_1904933 GO:0047118 biolink:MolecularActivity 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH. EC:1.3.1.40|RHEA:24268|KEGG_REACTION:R03463|MetaCyc:1.3.1.40-RXN go-plus.json 2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity|2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity http://purl.obolibrary.org/obo/GO_0047118 GO:1904932 biolink:BiologicalProcess negative regulation of cartilage condensation Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation. go-plus.json downregulation of cartilage condensation|down regulation of cartilage condensation|inhibition of cartilage condensation|down-regulation of cartilage condensation http://purl.obolibrary.org/obo/GO_1904932 CL:0002209 biolink:Cell intermediate epitheliocyte An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. go-plus.json undifferentiated columnar cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002209 GO:0047117 biolink:MolecularActivity enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+. EC:1.3.1.39|MetaCyc:1.3.1.39-RXN go-plus.json enoyl-acyl-carrier-protein reductase (NADPH, A-specific)|enoyl-ACp reductase activity|enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity|acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)|enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|enoyl-ACP reductase (NADPH, A-specific) activity http://purl.obolibrary.org/obo/GO_0047117 GO:1904931 biolink:MolecularActivity MCM complex binding Binding to an MCM complex. go-plus.json mini-chromosome maintenance complex binding http://purl.obolibrary.org/obo/GO_1904931 GO:0047116 biolink:MolecularActivity 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol. EC:1.3.1.25|RHEA:11560|MetaCyc:1.3.1.25-RXN go-plus.json (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)|DHB dehydrogenase activity|3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity|2-hydro-1,2-dihydroxybenzoate dehydrogenase activity|DHBDH activity|3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity|dihydrodihydroxybenzoate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047116 GO:1904930 biolink:CellularComponent amphisome membrane Any membrane that is part of an amphisome. go-plus.json http://purl.obolibrary.org/obo/GO_1904930 GO:0047115 biolink:MolecularActivity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol. RHEA:16729|EC:1.3.1.20|MetaCyc:1.3.1.20-RXN go-plus.json trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity|dihydrodiol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047115 GO:0047114 biolink:MolecularActivity kynurenate-7,8-dihydrodiol dehydrogenase activity Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH. EC:1.3.1.18|RHEA:22248|MetaCyc:1.3.1.18-RXN|KEGG_REACTION:R03251 go-plus.json 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity|7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity|7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0047114 GO:0047113 biolink:MolecularActivity aldehyde dehydrogenase (quinone) activity Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol. MetaCyc:1.2.99.3-RXN|RHEA:13881|EC:1.2.5.2 go-plus.json aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity|aldehyde dehydrogenase (pyrroloquinoline-quinone)|aldehyde dehydrogenase (acceptor) activity http://purl.obolibrary.org/obo/GO_0047113 GO:0047112 biolink:MolecularActivity pyruvate oxidase activity Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2). RHEA:20848|KEGG_REACTION:R00207|MetaCyc:1.2.3.3-RXN|EC:1.2.3.3 go-plus.json phosphate-dependent pyruvate oxidase activity|pyruvate:oxygen 2-oxidoreductase (phosphorylating)|pyruvic oxidase activity http://purl.obolibrary.org/obo/GO_0047112 CL:0002202 biolink:Cell epithelial cell of tracheobronchial tree An epithelial cell of the tracheobronchial tree. go-plus.json http://purl.obolibrary.org/obo/CL_0002202 GO:0047122 biolink:MolecularActivity quinaldate 4-oxidoreductase activity Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate. RHEA:16697|MetaCyc:1.3.99.18-RXN|EC:1.3.99.18|KEGG_REACTION:R03687 go-plus.json quinaldic acid 4-oxidoreductase activity|quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating) http://purl.obolibrary.org/obo/GO_0047122 GO:0047121 biolink:MolecularActivity isoquinoline 1-oxidoreductase activity Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one. MetaCyc:1.3.99.16-RXN|KEGG_REACTION:R05151|EC:1.3.99.16|RHEA:11588 go-plus.json isoquinoline:acceptor 1-oxidoreductase (hydroxylating) http://purl.obolibrary.org/obo/GO_0047121 GO:0047120 biolink:MolecularActivity (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH. MetaCyc:1.3.1.53-RXN|RHEA:10744|KEGG_REACTION:R01633|EC:1.3.1.53|UM-BBD_reactionID:r0151 go-plus.json dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)|(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity|terephthalate 1,2-cis-dihydrodiol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047120 GO:1904949 biolink:CellularComponent ATPase complex A protein complex which is capable of ATPase activity. go-plus.json VPS4 complex http://purl.obolibrary.org/obo/GO_1904949 GO:1904948 biolink:BiologicalProcess midbrain dopaminergic neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron. go-plus.json midbrain DA neurogenesis|midbrain dopaminergic neuron production|DA neurogenesis from midbrain floor plate|mDA neuron differentiation http://purl.obolibrary.org/obo/GO_1904948 GO:1904947 biolink:BiologicalProcess folate import into mitochondrion The process in which folic acid is transported from the cytosol into the mitochondrial matrix. go-plus.json folic acid import into mitochondrion http://purl.obolibrary.org/obo/GO_1904947 GO:1904946 biolink:BiologicalProcess obsolete cellular response to cobalt(II) acetate OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904946 CL:0002218 biolink:Cell immature dendritic epithelial T cell precursor A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. go-plus.json immature DEC precursor|immature DETC precursor http://purl.obolibrary.org/obo/CL_0002218 GO:1904945 biolink:BiologicalProcess obsolete response to cobalt(II) acetate OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904945 GO:0047129 biolink:MolecularActivity opine dehydrogenase activity Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate. RHEA:21592|MetaCyc:1.5.1.28-RXN|EC:1.5.1.28|KEGG_REACTION:R03732 go-plus.json (2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)|(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming) http://purl.obolibrary.org/obo/GO_0047129 GO:1904944 biolink:BiologicalProcess positive regulation of cardiac ventricle formation Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. go-plus.json upregulation of cardiac ventricle formation|up regulation of cardiac ventricle formation|activation of cardiac ventricle formation|up-regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1904944 GO:0047128 biolink:MolecularActivity 1,2-dehydroreticulinium reductase (NADPH) activity Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH. KEGG_REACTION:R04695|MetaCyc:1.5.1.27-RXN|EC:1.5.1.27|RHEA:17569 go-plus.json (R)-reticuline:NADP+ oxidoreductase activity|1,2-dehydroreticulinium ion reductase activity http://purl.obolibrary.org/obo/GO_0047128 GO:1904943 biolink:BiologicalProcess negative regulation of cardiac ventricle formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. go-plus.json down regulation of cardiac ventricle formation|downregulation of cardiac ventricle formation|down-regulation of cardiac ventricle formation|inhibition of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1904943 GO:0047127 biolink:MolecularActivity thiomorpholine-carboxylate dehydrogenase activity Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate. MetaCyc:1.5.1.25-RXN|EC:1.5.1.25|Reactome:R-HSA-5693347 go-plus.json ketimine reductase activity|thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity|ketimine-reducing enzyme http://purl.obolibrary.org/obo/GO_0047127 GO:1904942 biolink:BiologicalProcess regulation of cardiac ventricle formation Any process that modulates the frequency, rate or extent of cardiac ventricle formation. go-plus.json http://purl.obolibrary.org/obo/GO_1904942 GO:1904941 biolink:BiologicalProcess positive regulation of DNA nucleotidylexotransferase activity Any process that activates or increases the frequency, rate or extent of DNA nucleotidylexotransferase activity. go-plus.json up regulation of terminal deoxynucleotide transferase activity|up regulation of terminal transferase activity|up regulation of terminal addition enzyme activity|activation of terminal deoxynucleotide transferase activity|activation of terminal transferase activity|upregulation of terminal deoxyribonucleotidyltransferase activity|positive regulation of terminal deoxynucleotide transferase activity|upregulation of TdT|upregulation of DNA nucleotidylexotransferase activity|upregulation of deoxynucleotidyl terminal transferase activity|positive regulation of terminal transferase activity|up-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of terminal addition enzyme activity|activation of deoxyribonucleic nucleotidyltransferase activity|up-regulation of deoxyribonucleic nucleotidyltransferase activity|upregulation of addase activity|up regulation of terminal deoxynucleotidyltransferase activity|activation of terminal addition enzyme activity|activation of terminal deoxynucleotidyltransferase activity|up-regulation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of terminal deoxynucleotidyltransferase activity|activation of deoxynucleotidyl terminal transferase activity|activation of DNA nucleotidylexotransferase activity|up-regulation of DNA nucleotidylexotransferase activity|up-regulation of deoxynucleotidyl terminal transferase activity|upregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|up regulation of terminal deoxyribonucleotidyltransferase activity|up regulation of TdT|up-regulation of terminal deoxynucleotide transferase activity|activation of terminal deoxyribonucleotidyltransferase activity|up-regulation of terminal transferase activity|positive regulation of terminal deoxyribonucleotidyltransferase activity|positive regulation of TdT|up-regulation of terminal addition enzyme activity|positive regulation of deoxyribonucleic nucleotidyltransferase activity|up regulation of addase activity|activation of addase activity|positive regulation of addase activity|up regulation of deoxyribonucleic nucleotidyltransferase activity|upregulation of deoxyribonucleic acid nucleotidyltransferase activity|activation of TdT|up-regulation of terminal deoxynucleotidyltransferase activity|up regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|upregulation of terminal deoxynucleotide transferase activity|positive regulation of deoxynucleotidyl terminal transferase activity|upregulation of terminal transferase activity|activation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|upregulation of terminal addition enzyme activity|up regulation of deoxynucleotidyl terminal transferase activity|up regulation of DNA nucleotidylexotransferase activity|positive regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|up-regulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of TdT|upregulation of deoxyribonucleic nucleotidyltransferase activity|up regulation of deoxyribonucleic acid nucleotidyltransferase activity|up-regulation of addase activity|activation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of deoxyribonucleic acid nucleotidyltransferase activity|upregulation of terminal deoxynucleotidyltransferase activity http://purl.obolibrary.org/obo/GO_1904941 GO:0047126 biolink:MolecularActivity N5-(carboxyethyl)ornithine synthase activity Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate. RHEA:18661|MetaCyc:1.5.1.24-RXN|EC:1.5.1.24|KEGG_REACTION:R00666 go-plus.json 5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)|N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming) http://purl.obolibrary.org/obo/GO_0047126 GO:1904940 biolink:BiologicalProcess negative regulation of DNA nucleotidylexotransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA nucleotidylexotransferase activity. go-plus.json down regulation of terminal deoxynucleotidyltransferase activity|inhibition of DNA nucleotidylexotransferase activity|inhibition of deoxynucleotidyl terminal transferase activity|negative regulation of deoxyribonucleic acid nucleotidyltransferase activity|down-regulation of deoxyribonucleic acid nucleotidyltransferase activity|inhibition of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|downregulation of terminal deoxynucleotidyltransferase activity|down regulation of terminal deoxyribonucleotidyltransferase activity|down regulation of TdT|down-regulation of terminal deoxynucleotide transferase activity|negative regulation of terminal deoxynucleotide transferase activity|down-regulation of terminal transferase activity|negative regulation of terminal transferase activity|down-regulation of terminal addition enzyme activity|down regulation of addase activity|negative regulation of terminal addition enzyme activity|inhibition of deoxyribonucleic acid nucleotidyltransferase activity|downregulation of terminal deoxyribonucleotidyltransferase activity|downregulation of TdT|negative regulation of deoxyribonucleic nucleotidyltransferase activity|down-regulation of deoxyribonucleic nucleotidyltransferase activity|downregulation of addase activity|inhibition of terminal deoxynucleotide transferase activity|negative regulation of terminal deoxynucleotidyltransferase activity|inhibition of terminal transferase activity|down-regulation of terminal deoxynucleotidyltransferase activity|down regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of DNA nucleotidylexotransferase activity|negative regulation of deoxynucleotidyl terminal transferase activity|down-regulation of deoxynucleotidyl terminal transferase activity|down-regulation of terminal deoxyribonucleotidyltransferase activity|negative regulation of terminal deoxyribonucleotidyltransferase activity|downregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of TdT|negative regulation of TdT|inhibition of terminal addition enzyme activity|downregulation of deoxyribonucleic nucleotidyltransferase activity|down regulation of deoxyribonucleic acid nucleotidyltransferase activity|negative regulation of addase activity|down-regulation of addase activity|inhibition of terminal deoxynucleotidyltransferase activity|down regulation of deoxyribonucleic nucleotidyltransferase activity|inhibition of terminal deoxyribonucleotidyltransferase activity|down regulation of terminal deoxynucleotide transferase activity|downregulation of deoxyribonucleic acid nucleotidyltransferase activity|down regulation of terminal transferase activity|inhibition of deoxyribonucleic nucleotidyltransferase activity|downregulation of deoxynucleotidyl terminal transferase activity|downregulation of DNA nucleotidylexotransferase activity|down regulation of terminal addition enzyme activity|inhibition of addase activity|negative regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|downregulation of terminal deoxynucleotide transferase activity|downregulation of terminal transferase activity|inhibition of TdT|down regulation of deoxynucleotidyl terminal transferase activity|down regulation of DNA nucleotidylexotransferase activity|downregulation of terminal addition enzyme activity http://purl.obolibrary.org/obo/GO_1904940 GO:0047125 biolink:MolecularActivity delta1-piperideine-2-carboxylate reductase activity Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate. MetaCyc:RXN-8166|RHEA:12524|EC:1.5.1.21 go-plus.json 1,2-didehydropipecolate reductase activity|delta 1-piperideine-2-carboxylate reductase activity|1,2-didehydropipecolic reductase activity|D1-piperideine-2-carboxylate reductase activity|L-pipecolate:NADP+ 2-oxidoreductase activity|P2C reductase activity http://purl.obolibrary.org/obo/GO_0047125 GO:0047124 biolink:MolecularActivity L-erythro-3,5-diaminohexanoate dehydrogenase activity Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+). RHEA:19633|MetaCyc:1.4.1.11-RXN|EC:1.4.1.11|KEGG_REACTION:R03349 go-plus.json L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)|L-3,5-diaminohexanoate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0047124 GO:0047123 biolink:MolecularActivity quinoline-4-carboxylate 2-oxidoreductase activity Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2). MetaCyc:1.3.99.19-RXN|EC:1.3.99.19|KEGG_REACTION:R05183|RHEA:14949 go-plus.json quinoline-4-carboxylic acid 2-oxidoreductase activity|quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating) http://purl.obolibrary.org/obo/GO_0047123 CHEBI:50413 biolink:ChemicalSubstance hydroxyaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_50413 CHEBI:50411 biolink:ChemicalSubstance one-colour indicator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50411 CHEBI:50410 biolink:ChemicalSubstance colour indicator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50410 CHEBI:50418 biolink:ChemicalSubstance 4-hydroxyphenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50418 CHEBI:25450 biolink:ChemicalSubstance myo-inositol trisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25450 CHEBI:50402 biolink:ChemicalSubstance androstanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50402 CHEBI:50401 biolink:ChemicalSubstance cholestanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50401 CHEBI:50406 biolink:ChemicalSubstance probe go-plus.json http://purl.obolibrary.org/obo/CHEBI_50406 CHEBI:50404 biolink:ChemicalSubstance lipoprotein cholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50404 CHEBI:50403 biolink:ChemicalSubstance ergostanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50403 CHEBI:50408 biolink:ChemicalSubstance visual indicator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50408 UBERON:0002870 biolink:AnatomicalEntity dorsal motor nucleus of vagus nerve A cranial nerve nucleus for the vagus nerve in the medulla that lies under the floor of the fourth ventricle. It mostly serves parasympathetic vagal functions in the gastrointestinal tract, lungs, and other thoracic and abdominal vagal innervations. The cell bodies for the preganglionic parasympathetic vagal neurons that innervate the heart reside in the nucleus ambiguus.[WP,unvetted]. go-plus.json dorsal vagal nucleus|dorsal motor nucleus of vagus|nucleus dorsalis nervi vagi|dorsal nucleus of vagus nerve|dorsal vagal nucleus|nucleus alaris (Oertel)|dorsal motor nucleus of the vagus nerve|nucleus posterior nervi vagi|vagus nucleus|posterior nucleus of vagus nerve|dorsal motor vagal nucleus|dorsal motor nucleus of the vagus|dorsal nucleus of the vagus nerve|dorsal efferent nucleus of vagus|dorsal motor nucleus of the vagus (vagal nucleus)|dorsal motor nucleus|nucleus vagalis dorsalis|dorsal motor nucleus of vagus nerve|nucleus dorsalis motorius nervi vagi|dorsal motor nucleus of vagus X nerve|nucleus alaris http://purl.obolibrary.org/obo/UBERON_0002870 UBERON:0002872 biolink:AnatomicalEntity inferior salivatory nucleus In the brain, the inferior salivatory nucleus is a cluster of neurons controlling the parasympathetic input to the parotid gland. It is one of the components of the glossopharyngeal nerve. [WP,unvetted]. go-plus.json inferior salivary nucleus|nucleus salivatorius caudalis|nucleus salivatorius inferior|nucleus salivarius inferior|inferior salivatary nucleus|nucleus salivatorius inferior nervi glossopharyngei http://purl.obolibrary.org/obo/UBERON_0002872 UBERON:0002871 biolink:AnatomicalEntity hypoglossal nucleus Nucleus forming a longitudinal cell column in the medulla, close beneath the floor of the 4th ventricle, containing motor neurons that innervate the muscles of the tongue (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 453) go-plus.json nucleus of hypoglossal nerve|hypoglossal XII nucleus|nucleus nervi hypoglossi|nucleus nervi hypoglossi|twelfth cranial nerve nucleus|hypoglossal nerve nucleus|nucleus hypoglossalis|hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0002871 CHEBI:25435 biolink:ChemicalSubstance mutagen go-plus.json http://purl.obolibrary.org/obo/CHEBI_25435 CHEBI:74402 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74402 CHEBI:74401 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74401 CHEBI:25432 biolink:ChemicalSubstance muramic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_25432 CHEBI:74406 biolink:ChemicalSubstance 3-vinylbacteriochlorophyllide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74406 CHEBI:74405 biolink:ChemicalSubstance (R)-3-hydroxydecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74405 CHEBI:25438 biolink:ChemicalSubstance mycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25438 CHEBI:25437 biolink:ChemicalSubstance mycolates go-plus.json http://purl.obolibrary.org/obo/CHEBI_25437 CHEBI:74408 biolink:ChemicalSubstance 3-dimethylallyl-4-hydroxyphenylpyruvate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74408 chebi_ph7_3 CHEBI:74409 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74409 CHEBI:25430 biolink:ChemicalSubstance monoatomic polycation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25430 CHEBI:74400 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74400 CHEBI:74413 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74413 CHEBI:25446 biolink:ChemicalSubstance myo-inositol monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25446 CHEBI:25445 biolink:ChemicalSubstance myo-inositol hexakisphosphates go-plus.json http://purl.obolibrary.org/obo/CHEBI_25445 CHEBI:74415 biolink:ChemicalSubstance N(6)-dimethylallyladenine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74415 chebi_ph7_3 CHEBI:25444 biolink:ChemicalSubstance myo-inositol cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25444 CHEBI:74414 biolink:ChemicalSubstance 3-ureidoisobutyrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74414 chebi_ph7_3 CHEBI:25443 biolink:ChemicalSubstance myo-inositol bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25443 CHEBI:74417 biolink:ChemicalSubstance 2-methylthio-N(6)-dimethylallyladenine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74417 chebi_ph7_3 CHEBI:74416 biolink:ChemicalSubstance 2-thio-N(6)-dimethylallyladenine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74416 chebi_ph7_3 CHEBI:25449 biolink:ChemicalSubstance myo-inositol tetrakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25449 CHEBI:74419 biolink:ChemicalSubstance 2-thio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74419 chebi_ph7_3 CHEBI:25448 biolink:ChemicalSubstance myo-inositol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25448 CHEBI:25447 biolink:ChemicalSubstance myo-inositol pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25447 CHEBI:74418 biolink:ChemicalSubstance N(6)-L-threonylcarbamoyladenine 5'-monophosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74418 chebi_ph7_3 CHEBI:25442 biolink:ChemicalSubstance mycotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25442 CHEBI:25441 biolink:ChemicalSubstance mycothiols go-plus.json http://purl.obolibrary.org/obo/CHEBI_25441 CHEBI:74411 biolink:ChemicalSubstance adenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74411 chebi_ph7_3 GO:0106199 biolink:MolecularActivity obsolete translocase activity acting on amino acids and peptides linked to oxidoreductase reactions OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to oxidoreductase reactions. EC:7.4.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0106199 CHEBI:74424 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74424 chebi_ph7_3 CHEBI:25413 biolink:ChemicalSubstance monounsaturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25413 GO:0106198 biolink:MolecularActivity obsolete translocase activity acting on inorganic anions linked to a decarboxylation reaction OBSOLETE. Catalysis of the translocation of an inorganic anion linked to a decarboxylation reaction. EC:7.3.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0106198 CHEBI:25412 biolink:ChemicalSubstance monoterpenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25412 GO:0106197 biolink:MolecularActivity obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a diphosphate OBSOLETE. Catalysis of the translocation of inorganic anions llinked to the hydrolysis of a diphosphate. EC:7.3.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0106197 CHEBI:25411 biolink:ChemicalSubstance monoterpenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_25411 CHEBI:74426 biolink:ChemicalSubstance (10Z,13Z,16Z)-3-oxodocosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74426 chebi_ph7_3 GO:0106196 biolink:MolecularActivity obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate. EC:7.3.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0106196 UBERON:0012240 biolink:AnatomicalEntity urethral meatus external opening or orifice of the urethra through which urine and seminal fluid (in males only) leave the body; in males the meatus presents as a vertical slit normally positioned at the tip of glans penis; in females the meatus is located between the clitoris and the vagina in the vulvular vestibule of the female genitalia[MP]. go-plus.json urethral meatus|orificium urethrae externum|external meatus of urethra|external urethral orifice|orificium urethræ externum|urinary meatus|meatus urinarius|external urethral ostium|external urinary meatus http://purl.obolibrary.org/obo/UBERON_0012240 CHEBI:74428 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74428 CHEBI:74427 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z)-3-oxotetracosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74427 chebi_ph7_3 CHEBI:25414 biolink:ChemicalSubstance monoatomic monocation go-plus.json http://purl.obolibrary.org/obo/CHEBI_25414 chebi_ph7_3 CHEBI:74429 biolink:ChemicalSubstance 7-methylguanosine 5'-triphosphate(2-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_74429 chebi_ph7_3 UBERON:0012242 biolink:AnatomicalEntity internal urethral orifice the usually crescent-shaped opening of the urinary bladder into the urethra, placed at the anteroinferior angle (apex) of the urinary bladder trigone go-plus.json internal urethral ostium|internal urethral ostium|internal urinary meatus|ostium urethrae internum|vesicourethral orifice|orificium urethrae internum|internal meatus of urethra|ostium orificium internum|internal urethral orifice of urinary bladder http://purl.obolibrary.org/obo/UBERON_0012242 UBERON:0012241 biolink:AnatomicalEntity male urethral meatus A urethral meatus that is part of a male urethra[Automatically generated definition]. go-plus.json urethral meatus of penile urethra|distal urethral opening of male|male urethra ostium|external orifice of male urethra|ostium urethrae externum (urethra masculina)|external urethral orifice (male)|urethral opening of penile urethra http://purl.obolibrary.org/obo/UBERON_0012241 UBERON:0012248 biolink:AnatomicalEntity cervical mucosa Lining of the head of the uterus (cervix); contains large branched glands; does not undergo sloughing. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012248 UBERON:0012247 biolink:AnatomicalEntity cervical gland mucus-secreting glands in the mucosa of the uterine cervix go-plus.json glandulae cervicales http://purl.obolibrary.org/obo/UBERON_0012247 UBERON:0012239 biolink:AnatomicalEntity urinary bladder vasculature network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP] go-plus.json blood vessel of bladder|set of urinary bladder blood vessels|bladder vasculature|blood vessels of bladder http://purl.obolibrary.org/obo/UBERON_0012239 CHEBI:25418 biolink:ChemicalSubstance morphinane alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25418 CHEBI:74420 biolink:ChemicalSubstance 2-methylthio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74420 chebi_ph7_3 CHEBI:74422 biolink:ChemicalSubstance 4'-demethylepipodophyllotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_74422 chebi_ph7_3 CHEBI:74434 biolink:ChemicalSubstance N(2),N(2),N(7)-trimethylguanosine 5'-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74434 chebi_ph7_3 CHEBI:25422 biolink:ChemicalSubstance muconate semialdehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_25422 CHEBI:74436 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74436 CHEBI:25427 biolink:ChemicalSubstance mugineic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_25427 CHEBI:25426 biolink:ChemicalSubstance mugineic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25426 CHEBI:74431 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74431 CHEBI:74432 biolink:ChemicalSubstance N(2),N(2),N(7)-trimethylguanosine 5'-triphosphate(2-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_74432 chebi_ph7_3 CHEBI:74446 biolink:ChemicalSubstance 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74446 CHEBI:74445 biolink:ChemicalSubstance 2'-O-methylguanosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74445 chebi_ph7_3 CHEBI:74447 biolink:ChemicalSubstance 5-methyluridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74447 chebi_ph7_3 CHEBI:74449 biolink:ChemicalSubstance N(6)-methyladenosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74449 chebi_ph7_3 CHEBI:74442 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z,35Z)-3-oxooctatriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74442 CHEBI:74444 biolink:ChemicalSubstance 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine 5'-phosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74444 CHEBI:74443 biolink:ChemicalSubstance 5,6-dihydrouridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74443 chebi_ph7_3 CHEBI:74457 biolink:ChemicalSubstance N-tetracosenoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74457 chebi_ph7_3 CHEBI:25401 biolink:ChemicalSubstance monomethoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25401 CHEBI:25400 biolink:ChemicalSubstance monoiodotyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25400 CHEBI:74459 biolink:ChemicalSubstance (R)-3-hydroxypalmitoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74459 CHEBI:25405 biolink:ChemicalSubstance monophosphoglyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25405 PR:000012621 biolink:Protein progesterone receptor A protein that is a translation product of the human PGR gene or a 1:1 ortholog thereof. go-plus.json PR|nuclear receptor subfamily 3 group C member 3|NR3C3|PGR http://purl.obolibrary.org/obo/PR_000012621 CHEBI:25409 biolink:ChemicalSubstance monoterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25409 CHEBI:74451 biolink:ChemicalSubstance (R)-3-hydroxylauroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74451 CHEBI:25408 biolink:ChemicalSubstance monoterpene ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25408 CHEBI:74450 biolink:ChemicalSubstance N-(15Z)-tetracosenoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74450 chebi_ph7_3 CHEBI:74452 biolink:ChemicalSubstance NMNH go-plus.json http://purl.obolibrary.org/obo/CHEBI_74452 UBERON:0002894 biolink:AnatomicalEntity olfactory cortex Aggregate brain region defined as those areas of cerebral cortex receiving direct synaptic input from the olfactory bulb (Price, 1973). It usually includes the piriform cortex and sometimes other areas. go-plus.json olfactory areas|archeocortex|olfactory lobe|archaeocortex http://purl.obolibrary.org/obo/UBERON_0002894 CHEBI:74455 biolink:ChemicalSubstance 5-methylaminomethyl-2-thiouridine 5'-monophosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74455 chebi_ph7_3 UBERON:0002893 biolink:AnatomicalEntity nucleus of lateral olfactory tract go-plus.json nucleus of tractus olfactorius lateralis|lateral olfactory tract nucleus|nucleus of the lateral olfactory tract|nucleus of the lateral olfactory tract (ganser)|nucleus striae olfactoriae lateralis|NLOT|nucleus of the olfactory tract http://purl.obolibrary.org/obo/UBERON_0002893 CHEBI:74454 biolink:ChemicalSubstance 5-aminomethyl-2-thiouridine 5'-monophosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74454 chebi_ph7_3 GO:0072298 biolink:BiologicalProcess regulation of metanephric glomerulus development Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072298 GO:0072297 biolink:BiologicalProcess specification of metanephric proximal tubule identity The process in which the proximal tubule of the metanephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072297 GO:0072296 biolink:BiologicalProcess specification of metanephric loop of Henle identity The process in which the loop of Henle of the metanephric nephron acquires its identity. go-plus.json specification of metanephric intermediate tubule identity http://purl.obolibrary.org/obo/GO_0072296 GO:0072295 biolink:BiologicalProcess specification of metanephric distal tubule identity The process in which the distal tubule of the metanephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072295 CHEBI:50498 biolink:ChemicalSubstance vaccenate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_50498 chebi_ph7_3 GO:0072294 biolink:BiologicalProcess specification of metanephric connecting tubule identity The process in which the connecting tubule of the metanephric nephron acquires its identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072294 GO:0072293 biolink:BiologicalProcess specification of metanephric nephron tubule identity The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity. go-plus.json http://purl.obolibrary.org/obo/GO_0072293 GO:0072292 biolink:BiologicalProcess epithelial cell migration involved in metanephric proximal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072292 GO:0072291 biolink:BiologicalProcess epithelial cell migration involved in metanephric distal tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072291 GO:0072290 biolink:BiologicalProcess epithelial cell migration involved in metanephric nephron tubule morphogenesis The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072290 CHEBI:132525 biolink:ChemicalSubstance oligosaccharide-(1->4)-N-acetyl-beta-D-glucosamine-(1->4)-N-acetyl-alpha-D-glucosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132525 chebi_ph7_3 GO:1900077 biolink:BiologicalProcess negative regulation of cellular response to insulin stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus. go-plus.json inhibition of cellular response to insulin stimulus|down regulation of cellular response to insulin stimulus|downregulation of cellular response to insulin stimulus|down-regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_1900077 CHEBI:132529 biolink:ChemicalSubstance N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132529 chebi_ph7_3 GO:1900076 biolink:BiologicalProcess regulation of cellular response to insulin stimulus Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1900076 GO:1900079 biolink:BiologicalProcess regulation of arginine biosynthetic process Any process that modulates the frequency, rate or extent of arginine biosynthetic process. go-plus.json regulation of arginine synthesis|regulation of arginine formation|regulation of arginine biosynthesis|regulation of arginine anabolism http://purl.obolibrary.org/obo/GO_1900079 GO:1900078 biolink:BiologicalProcess positive regulation of cellular response to insulin stimulus Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. go-plus.json up-regulation of cellular response to insulin stimulus|upregulation of cellular response to insulin stimulus|up regulation of cellular response to insulin stimulus|activation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_1900078 GO:1900084 biolink:BiologicalProcess regulation of peptidyl-tyrosine autophosphorylation Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. go-plus.json regulation of receptor tyrosine kinase autophosphorylation|regulation of tyrosine autophosphorylation http://purl.obolibrary.org/obo/GO_1900084 GO:1900083 biolink:BiologicalProcess obsolete regulation of Sertoli cell proliferation OBSOLETE. Any process that modulates the frequency, rate or extent of Sertoli cell proliferation. go-plus.json regulation of Sertoli cell proliferation http://purl.obolibrary.org/obo/GO_1900083 GO:1900086 biolink:BiologicalProcess positive regulation of peptidyl-tyrosine autophosphorylation Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. go-plus.json upregulation of tyrosine autophosphorylation|up regulation of peptidyl-tyrosine autophosphorylation|activation of peptidyl-tyrosine autophosphorylation|up-regulation of receptor tyrosine kinase autophosphorylation|activation of receptor tyrosine kinase autophosphorylation|up-regulation of tyrosine autophosphorylation|activation of tyrosine autophosphorylation|positive regulation of receptor tyrosine kinase autophosphorylation|up-regulation of peptidyl-tyrosine autophosphorylation|up regulation of receptor tyrosine kinase autophosphorylation|positive regulation of tyrosine autophosphorylation|up regulation of tyrosine autophosphorylation|upregulation of peptidyl-tyrosine autophosphorylation|upregulation of receptor tyrosine kinase autophosphorylation http://purl.obolibrary.org/obo/GO_1900086 CHEBI:132520 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132520 chebi_ph7_3 GO:1900085 biolink:BiologicalProcess negative regulation of peptidyl-tyrosine autophosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. go-plus.json down-regulation of peptidyl-tyrosine autophosphorylation|down-regulation of receptor tyrosine kinase autophosphorylation|negative regulation of receptor tyrosine kinase autophosphorylation|inhibition of peptidyl-tyrosine autophosphorylation|negative regulation of tyrosine autophosphorylation|down-regulation of tyrosine autophosphorylation|downregulation of receptor tyrosine kinase autophosphorylation|down regulation of receptor tyrosine kinase autophosphorylation|down regulation of peptidyl-tyrosine autophosphorylation|downregulation of tyrosine autophosphorylation|downregulation of peptidyl-tyrosine autophosphorylation|down regulation of tyrosine autophosphorylation|inhibition of receptor tyrosine kinase autophosphorylation|inhibition of tyrosine autophosphorylation http://purl.obolibrary.org/obo/GO_1900085 GO:1900080 biolink:BiologicalProcess positive regulation of arginine biosynthetic process Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process. go-plus.json positive regulation of arginine anabolism|up regulation of arginine anabolism|positive regulation of arginine synthesis|up regulation of arginine synthesis|positive regulation of arginine formation|up regulation of arginine biosynthesis|up regulation of arginine biosynthetic process|up regulation of arginine formation|activation of arginine biosynthetic process|activation of arginine biosynthesis|positive regulation of arginine biosynthesis|upregulation of arginine anabolism|upregulation of arginine synthesis|upregulation of arginine formation|up-regulation of arginine biosynthetic process|up-regulation of arginine anabolism|up-regulation of arginine biosynthesis|activation of arginine anabolism|up-regulation of arginine synthesis|activation of arginine synthesis|up-regulation of arginine formation|activation of arginine formation|upregulation of arginine biosynthesis|upregulation of arginine biosynthetic process http://purl.obolibrary.org/obo/GO_1900080 CHEBI:132522 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132522 chebi_ph7_3 CHEBI:132521 biolink:ChemicalSubstance alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132521 chebi_ph7_3 GO:1900082 biolink:BiologicalProcess negative regulation of arginine catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process. go-plus.json down regulation of arginine breakdown|downregulation of arginine catabolic process|inhibition of arginine breakdown|downregulation of arginine catabolism|down regulation of arginine catabolic process|inhibition of arginine catabolic process|down-regulation of arginine catabolism|negative regulation of arginine catabolism|down-regulation of arginine degradation|negative regulation of arginine degradation|inhibition of arginine catabolism|down-regulation of arginine breakdown|negative regulation of arginine breakdown|downregulation of arginine degradation|down-regulation of arginine catabolic process|down regulation of arginine degradation|inhibition of arginine degradation|downregulation of arginine breakdown|down regulation of arginine catabolism http://purl.obolibrary.org/obo/GO_1900082 GO:1900081 biolink:BiologicalProcess regulation of arginine catabolic process Any process that modulates the frequency, rate or extent of arginine catabolic process. go-plus.json regulation of arginine catabolism|regulation of arginine degradation|regulation of arginine breakdown http://purl.obolibrary.org/obo/GO_1900081 CHEBI:132523 biolink:ChemicalSubstance alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132523 chebi_ph7_3 CHEBI:50492 biolink:ChemicalSubstance thiocarbonyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_50492 CHEBI:50491 biolink:ChemicalSubstance haloalkyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50491 GO:0072299 biolink:BiologicalProcess negative regulation of metanephric glomerulus development Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072299 GO:0072287 biolink:BiologicalProcess metanephric distal tubule morphogenesis The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072287 GO:0072286 biolink:BiologicalProcess metanephric connecting tubule development The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros. go-plus.json metanephric connecting duct development http://purl.obolibrary.org/obo/GO_0072286 GO:0072285 biolink:BiologicalProcess mesenchymal to epithelial transition involved in metanephric renal vesicle formation A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0072285 GO:0072284 biolink:BiologicalProcess metanephric S-shaped body morphogenesis The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072284 GO:0072283 biolink:BiologicalProcess metanephric renal vesicle morphogenesis The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072283 GO:0072282 biolink:BiologicalProcess metanephric nephron tubule morphogenesis The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072282 GO:0072281 biolink:BiologicalProcess mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072281 GO:0072280 biolink:BiologicalProcess establishment of planar polarity involved in metanephric nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros. go-plus.json establishment of planar cell polarity involved in metanephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072280 CHEBI:132537 biolink:ChemicalSubstance N(4)-(alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132537 chebi_ph7_3 CHEBI:132539 biolink:ChemicalSubstance fatty acid 20:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132539 CHEBI:132538 biolink:ChemicalSubstance fatty acid 20:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132538 GO:1900088 biolink:BiologicalProcess regulation of inositol biosynthetic process Any process that modulates the frequency, rate or extent of inositol biosynthetic process. go-plus.json regulation of inositol synthesis|regulation of inositol formation|regulation of inositol biosynthesis|regulation of vitamin Bh biosynthetic process|regulation of vitamin Bh biosynthesis|regulation of myo-inositol biosynthetic process|regulation of myo-inositol biosynthesis|regulation of inositol anabolism http://purl.obolibrary.org/obo/GO_1900088 CHEBI:49496 biolink:ChemicalSubstance gold(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49496 chebi_ph7_3 GO:1900087 biolink:BiologicalProcess positive regulation of G1/S transition of mitotic cell cycle Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. go-plus.json upregulation of G1/S transition of mitotic cell cycle|up regulation of G1/S transition of mitotic cell cycle|activation of G1/S transition of mitotic cell cycle|up-regulation of G1/S transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_1900087 GO:1900089 biolink:BiologicalProcess negative regulation of inositol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process. go-plus.json down-regulation of vitamin Bh biosynthetic process|downregulation of inositol synthesis|negative regulation of vitamin Bh biosynthetic process|down-regulation of vitamin Bh biosynthesis|negative regulation of vitamin Bh biosynthesis|down regulation of inositol anabolism|down-regulation of myo-inositol biosynthetic process|down-regulation of myo-inositol biosynthesis|negative regulation of myo-inositol biosynthesis|negative regulation of myo-inositol biosynthetic process|downregulation of inositol formation|inhibition of inositol biosynthetic process|down regulation of inositol synthesis|inhibition of inositol anabolism|down regulation of inositol formation|inhibition of inositol biosynthesis|inhibition of inositol synthesis|inhibition of vitamin Bh biosynthesis|inhibition of vitamin Bh biosynthetic process|inhibition of myo-inositol biosynthetic process|inhibition of inositol formation|inhibition of myo-inositol biosynthesis|down regulation of inositol biosynthetic process|down regulation of inositol biosynthesis|negative regulation of inositol anabolism|down regulation of vitamin Bh biosynthesis|down regulation of vitamin Bh biosynthetic process|down-regulation of inositol anabolism|downregulation of inositol biosynthetic process|downregulation of inositol biosynthesis|down regulation of myo-inositol biosynthesis|down regulation of myo-inositol biosynthetic process|negative regulation of inositol synthesis|downregulation of vitamin Bh biosynthesis|down-regulation of inositol synthesis|downregulation of vitamin Bh biosynthetic process|downregulation of myo-inositol biosynthesis|downregulation of myo-inositol biosynthetic process|negative regulation of inositol formation|down-regulation of inositol formation|downregulation of inositol anabolism|negative regulation of inositol biosynthesis|down-regulation of inositol biosynthesis|down-regulation of inositol biosynthetic process http://purl.obolibrary.org/obo/GO_1900089 GO:1900095 biolink:BiologicalProcess regulation of dosage compensation by inactivation of X chromosome Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. go-plus.json regulation of chromosome inactivation|regulation of Barr body formation|regulation of X chromosome inactivation http://purl.obolibrary.org/obo/GO_1900095 GO:1900094 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry Any regulation of transcription from RNA polymerase II promoter that is involved in determination of left/right symmetry. go-plus.json regulation of global transcription from Pol II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right symmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right symmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right asymmetry|regulation of transcription from Pol II promoter of determination of left/right symmetry|regulation of global transcription from Pol II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of transcription from Pol II promoter of determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_1900094 GO:1900097 biolink:BiologicalProcess positive regulation of dosage compensation by inactivation of X chromosome Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. go-plus.json upregulation of dosage compensation, by inactivation of X chromosome|up regulation of X chromosome inactivation|upregulation of Barr body formation|positive regulation of X chromosome inactivation|up regulation of chromosome inactivation|positive regulation of chromosome inactivation|activation of X chromosome inactivation|up-regulation of dosage compensation, by inactivation of X chromosome|activation of dosage compensation, by inactivation of X chromosome|activation of chromosome inactivation|up regulation of Barr body formation|up-regulation of X chromosome inactivation|positive regulation of Barr body formation|up-regulation of chromosome inactivation|activation of Barr body formation|up regulation of dosage compensation, by inactivation of X chromosome|upregulation of X chromosome inactivation|upregulation of chromosome inactivation|up-regulation of Barr body formation http://purl.obolibrary.org/obo/GO_1900097 GO:1900096 biolink:BiologicalProcess negative regulation of dosage compensation by inactivation of X chromosome Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. go-plus.json down regulation of chromosome inactivation|down regulation of dosage compensation, by inactivation of X chromosome|inhibition of dosage compensation, by inactivation of X chromosome|downregulation of X chromosome inactivation|inhibition of Barr body formation|downregulation of chromosome inactivation|down regulation of Barr body formation|negative regulation of X chromosome inactivation|down-regulation of X chromosome inactivation|downregulation of Barr body formation|negative regulation of chromosome inactivation|down-regulation of chromosome inactivation|down-regulation of dosage compensation, by inactivation of X chromosome|inhibition of X chromosome inactivation|down-regulation of Barr body formation|negative regulation of Barr body formation|inhibition of chromosome inactivation|downregulation of dosage compensation, by inactivation of X chromosome|down regulation of X chromosome inactivation http://purl.obolibrary.org/obo/GO_1900096 GO:1900091 biolink:BiologicalProcess regulation of raffinose biosynthetic process Any process that modulates the frequency, rate or extent of raffinose biosynthetic process. go-plus.json regulation of raffinose biosynthesis|regulation of raffinose anabolism|regulation of raffinose synthesis|regulation of raffinose formation http://purl.obolibrary.org/obo/GO_1900091 GO:1900090 biolink:BiologicalProcess positive regulation of inositol biosynthetic process Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process. go-plus.json activation of inositol synthesis|up regulation of inositol biosynthetic process|positive regulation of inositol anabolism|up regulation of inositol biosynthesis|activation of inositol biosynthetic process|positive regulation of inositol biosynthesis|activation of inositol formation|up regulation of inositol anabolism|up regulation of vitamin Bh biosynthesis|up regulation of vitamin Bh biosynthetic process|positive regulation of inositol synthesis|positive regulation of vitamin Bh biosynthetic process|up regulation of myo-inositol biosynthetic process|up regulation of myo-inositol biosynthesis|positive regulation of vitamin Bh biosynthesis|up regulation of inositol synthesis|positive regulation of inositol formation|positive regulation of myo-inositol biosynthetic process|activation of inositol biosynthesis|positive regulation of myo-inositol biosynthesis|up regulation of inositol formation|activation of vitamin Bh biosynthetic process|activation of vitamin Bh biosynthesis|upregulation of inositol anabolism|activation of myo-inositol biosynthesis|activation of myo-inositol biosynthetic process|up-regulation of inositol biosynthetic process|up-regulation of inositol biosynthesis|upregulation of inositol synthesis|up-regulation of vitamin Bh biosynthetic process|up-regulation of vitamin Bh biosynthesis|up-regulation of myo-inositol biosynthetic process|up-regulation of myo-inositol biosynthesis|upregulation of inositol formation|up-regulation of inositol anabolism|upregulation of inositol biosynthetic process|upregulation of inositol biosynthesis|upregulation of vitamin Bh biosynthetic process|upregulation of vitamin Bh biosynthesis|up-regulation of inositol synthesis|upregulation of myo-inositol biosynthesis|upregulation of myo-inositol biosynthetic process|activation of inositol anabolism|up-regulation of inositol formation http://purl.obolibrary.org/obo/GO_1900090 GO:1900093 biolink:BiologicalProcess positive regulation of raffinose biosynthetic process Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process. go-plus.json up regulation of raffinose formation|activation of raffinose anabolism|up-regulation of raffinose biosynthetic process|up-regulation of raffinose biosynthesis|positive regulation of raffinose formation|activation of raffinose biosynthetic process|activation of raffinose synthesis|up-regulation of raffinose anabolism|activation of raffinose formation|activation of raffinose biosynthesis|up-regulation of raffinose synthesis|positive regulation of raffinose biosynthesis|up-regulation of raffinose formation|up regulation of raffinose biosynthetic process|up regulation of raffinose biosynthesis|upregulation of raffinose anabolism|upregulation of raffinose synthesis|upregulation of raffinose formation|upregulation of raffinose biosynthetic process|upregulation of raffinose biosynthesis|up regulation of raffinose anabolism|positive regulation of raffinose anabolism|up regulation of raffinose synthesis|positive regulation of raffinose synthesis http://purl.obolibrary.org/obo/GO_1900093 GO:1900092 biolink:BiologicalProcess negative regulation of raffinose biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process. go-plus.json negative regulation of raffinose synthesis|down-regulation of raffinose synthesis|negative regulation of raffinose formation|down-regulation of raffinose formation|down-regulation of raffinose biosynthesis|negative regulation of raffinose biosynthesis|down-regulation of raffinose biosynthetic process|inhibition of raffinose anabolism|inhibition of raffinose synthesis|downregulation of raffinose biosynthetic process|inhibition of raffinose formation|down regulation of raffinose anabolism|downregulation of raffinose biosynthesis|downregulation of raffinose anabolism|down regulation of raffinose biosynthetic process|down regulation of raffinose biosynthesis|down regulation of raffinose synthesis|inhibition of raffinose biosynthetic process|down regulation of raffinose formation|downregulation of raffinose synthesis|downregulation of raffinose formation|inhibition of raffinose biosynthesis|negative regulation of raffinose anabolism|down-regulation of raffinose anabolism http://purl.obolibrary.org/obo/GO_1900092 GO:0072289 biolink:BiologicalProcess metanephric nephron tubule formation The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072289 GO:0072288 biolink:BiologicalProcess metanephric proximal tubule morphogenesis The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0072288 CHEBI:50477 biolink:ChemicalSubstance butyrate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_50477 chebi_ph7_3 CHEBI:132503 biolink:ChemicalSubstance fatty acid 18:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132503 CHEBI:132506 biolink:ChemicalSubstance N-arachidonoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132506 CHEBI:132505 biolink:ChemicalSubstance N-tetracosanoyltaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132505 GO:1900099 biolink:BiologicalProcess negative regulation of plasma cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation. go-plus.json down-regulation of plasma cell differentiation|down regulation of plasma cell development|downregulation of plasma cell development|inhibition of plasma cell differentiation|down-regulation of plasma cell development|negative regulation of plasma cell development|down regulation of plasma cell differentiation|downregulation of plasma cell differentiation|inhibition of plasma cell development http://purl.obolibrary.org/obo/GO_1900099 CHEBI:132508 biolink:ChemicalSubstance N-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]taurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132508 GO:1900098 biolink:BiologicalProcess regulation of plasma cell differentiation Any process that modulates the frequency, rate or extent of plasma cell differentiation. go-plus.json regulation of plasma cell development http://purl.obolibrary.org/obo/GO_1900098 CHEBI:132507 biolink:ChemicalSubstance N-[12(S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]taurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132507 CHEBI:132502 biolink:ChemicalSubstance fatty acid 18:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132502 CHEBI:50471 biolink:ChemicalSubstance primary arylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50471 chebi_ph7_3 CHEBI:50467 biolink:ChemicalSubstance trans-2-decenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50467 CHEBI:50465 biolink:ChemicalSubstance 2-decenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50465 CHEBI:50469 biolink:ChemicalSubstance EC 3.1.1.4 (phospholipase A2) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50469 CHEBI:132515 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132515 chebi_ph7_3 CHEBI:132517 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132517 chebi_ph7_3 CHEBI:132516 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132516 chebi_ph7_3 CHEBI:132519 biolink:ChemicalSubstance alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132519 chebi_ph7_3 CHEBI:132511 biolink:ChemicalSubstance alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132511 chebi_ph7_3 CHEBI:132510 biolink:ChemicalSubstance alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132510 chebi_ph7_3 CHEBI:50464 biolink:ChemicalSubstance cis-vaccenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50464 CHEBI:49468 biolink:ChemicalSubstance silver(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49468 chebi_ph7_3 UBERON:0002834 biolink:AnatomicalEntity cervical dorsal root ganglion go-plus.json cervical dorsal root ganglion|cervical spinal ganglion http://purl.obolibrary.org/obo/UBERON_0002834 UBERON:0002835 biolink:AnatomicalEntity thoracic dorsal root ganglion A dorsal root ganglion that is part of a thorax [Automatically generated definition]. go-plus.json dorsal root ganglion of thorax|thorax ganglion spinalis|thorax dorsal root ganglion|thoracic spinal ganglion|thoracic dorsal root ganglion|ganglion of dorsal root of thorax|thorax ganglion of dorsal root|ganglion spinalis of thorax http://purl.obolibrary.org/obo/UBERON_0002835 CHEBI:25491 biolink:ChemicalSubstance nematicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25491 CHEBI:50452 biolink:ChemicalSubstance 6-hydroxy-3-isopropenylheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50452 CHEBI:50451 biolink:ChemicalSubstance 6-hydroxy-3,7-dimethyloctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50451 CHEBI:50450 biolink:ChemicalSubstance 1-naphthylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50450 chebi_ph7_3 UBERON:0002827 biolink:AnatomicalEntity vestibulocochlear ganglion the group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia go-plus.json statoacoustic ganglia|auditory ganglion|acoustico-vestibular VIII ganglion|SAG|acoustic ganglion VIII|acoustic ganglion|vestibulocochlear VIII ganglion|ganglion VIII|nucleus nervi oculomotorii, pars ventralis|statoacoustic (VIII) ganglion|gVIII|nucleus nervi oculomotorii ventrolateralis|vestibulocochlear ganglia|statoacoustic VIII ganglion|auditory ganglion|statoacoustic ganglion http://purl.obolibrary.org/obo/UBERON_0002827 CHEBI:50446 biolink:ChemicalSubstance 3-(hydroxyamino)phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50446 chebi_ph7_3 CHEBI:50445 biolink:ChemicalSubstance EC 3.5.4.4 (adenosine deaminase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50445 UBERON:0002829 biolink:AnatomicalEntity dorsal cochlear nucleus The dorsal cochlear nucleus (DCN, also known as the 'tuberculum acousticum'), is a cortex-like structure on the dorso-lateral surface of the brainstem. Along with the ventral cochlear nucleus, it forms the cochlear nucleus, where all auditory nerve fibers from the cochlea form their first synapses. [WP,unvetted]. go-plus.json posterior cochlear nucleus|dorsal division of cochlear nucleus|nucleus cochlearis posterior|nucleus cochlearis dorsalis|dorsal coclear nucleus|DCo|tuberculum acousticum|dorsal cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002829 UBERON:0002828 biolink:AnatomicalEntity ventral cochlear nucleus The ventral cochlear nucleus (or anterior, or accessory), placed between the two divisions of the cochlear nerve, is on the ventral aspect of the inferior peduncle. Composed of several regions of distinct cell types, this nucleus serves primarily as a relay station for ascending auditory information. Bushy cells in the anterior ventral cochlear nucleus (AVCN), which receive end bulbs of held from auditory nerve fibers, project to the superior olivary complex through the trapezoid body and intermediate acoustic stria. Other cell types project to the lateral lemniscus and the inferior colliculus directly. [WP,unvetted]. go-plus.json nucleus acustici accessorici|ventral cochlear nucleus|nucleus cochlearis anterior|nucleus cochlearis ventralis|c1281209|ventral cochlear nuclei|ventral division of cochlear nucleus|accessory cochlear nucleus|ventral coclear nucleus|VCo|anterior cochlear nucleus http://purl.obolibrary.org/obo/UBERON_0002828 CHEBI:50448 biolink:ChemicalSubstance naphthylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50448 UBERON:0002824 biolink:AnatomicalEntity vestibular ganglion The ganglion of the vestibular nerve. It contains the cell bodies of the bipolar primary afferent neurons whose peripheral processes form synaptic contact with hair cells of the vestibular sensory end organs[WP,unvetted]. Distributed to the maculae of the utricle and saccule and to the ampullary crests of the semicircular ducts. The vestibular fibers arise in bipolar cells in the vestibular ganglion in the internal acoustic meatus. go-plus.json vestibulocochlear VIII ganglion vestibular component|vestibulocochlear ganglion vestibular component|nucleus nervi oculomotorii, pars medialis|Scarpa's ganglion|vestibular part of vestibulocochlear ganglion http://purl.obolibrary.org/obo/UBERON_0002824 CHEBI:50447 biolink:ChemicalSubstance (S)-carnitinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50447 chebi_ph7_3 CHEBI:50442 biolink:ChemicalSubstance N-substituted cadaverine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50442 CHEBI:50441 biolink:ChemicalSubstance N-substituted diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50441 CHEBI:25479 biolink:ChemicalSubstance naphthalenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25479 CHEBI:25478 biolink:ChemicalSubstance naphthalenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25478 CHEBI:25477 biolink:ChemicalSubstance naphthalenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_25477 UBERON:0002812 biolink:AnatomicalEntity left cerebral hemisphere A cerebral hemisphere that is in the left side of a brain. go-plus.json left hemisphere http://purl.obolibrary.org/obo/UBERON_0002812 UBERON:0002811 biolink:AnatomicalEntity left frontal lobe A frontal cortex that is part of a left cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002811 OBO:pr#lacks_part biolink:OntologyClass lacks_part go-plus.json http://purl.obolibrary.org/obo/pr#lacks_part CHEBI:50436 biolink:ChemicalSubstance 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50436 chebi_ph7_3 UBERON:0002813 biolink:AnatomicalEntity right cerebral hemisphere A cerebral hemisphere that is in the right side of a brain. go-plus.json right hemisphere http://purl.obolibrary.org/obo/UBERON_0002813 UBERON:0002805 biolink:AnatomicalEntity right limbic lobe A limbic lobe that is part of a right cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002805 UBERON:0002804 biolink:AnatomicalEntity left limbic lobe A limbic lobe that is part of a left cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002804 CHEBI:50427 biolink:ChemicalSubstance platelet aggregation inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50427 UBERON:0002803 biolink:AnatomicalEntity right parietal lobe Parietal lobe of the right hemisphere of the brain go-plus.json http://purl.obolibrary.org/obo/UBERON_0002803 CHEBI:50425 biolink:ChemicalSubstance inorganic disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50425 UBERON:0002802 biolink:AnatomicalEntity left parietal lobe Parietal lobe of the left hemisphere of the brain go-plus.json http://purl.obolibrary.org/obo/UBERON_0002802 CHEBI:25482 biolink:ChemicalSubstance naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25482 CHEBI:25481 biolink:ChemicalSubstance naphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25481 CHEBI:50429 biolink:ChemicalSubstance (Z)-glutaconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50429 UBERON:0002809 biolink:AnatomicalEntity right temporal lobe A temporal lobe that is part of a right cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002809 UBERON:0002808 biolink:AnatomicalEntity left temporal lobe A temporal lobe that is part of a left cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002808 CHEBI:49432 biolink:ChemicalSubstance 5-hydroxyectoine go-plus.json http://purl.obolibrary.org/obo/CHEBI_49432 CHEBI:25483 biolink:ChemicalSubstance naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25483 UBERON:0002810 biolink:AnatomicalEntity right frontal lobe A frontal cortex that is part of a right cerebral hemisphere. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002810 GO:0072210 biolink:BiologicalProcess metanephric nephron development The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. go-plus.json http://purl.obolibrary.org/obo/GO_0072210 GO:0047254 biolink:MolecularActivity 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP. RHEA:15541|EC:2.4.1.202|MetaCyc:2.4.1.202-RXN go-plus.json UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity|uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity|UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047254 GO:0047253 biolink:MolecularActivity alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP. EC:2.4.1.201|RHEA:19945|MetaCyc:2.4.1.201-RXN go-plus.json mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity|UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity|N-acetylglucosaminyltransferase VI activity|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI|alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047253 GO:0047252 biolink:MolecularActivity beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate. EC:2.4.1.199|MetaCyc:2.4.1.199-RXN go-plus.json mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity|beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0047252 GO:0047251 biolink:MolecularActivity thiohydroximate beta-D-glucosyltransferase activity Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP. MetaCyc:2.4.1.195-RXN|EC:2.4.1.195|RHEA:13757 go-plus.json desulfoglucosinolate-uridine diphosphate glucosyltransferase activity|UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity|N-hydroxythioamide S-beta-glucosyltransferase activity|thiohydroximate glucosyltransferase activity|uridine diphosphoglucose-thiohydroximate glucosyltransferase activity|UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity|thiohydroximate S-glucosyltransferase activity|UDPG:thiohydroximate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047251 GO:0047250 biolink:MolecularActivity 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP. RHEA:15153|MetaCyc:2.4.1.194-RXN|EC:2.4.1.194|KEGG_REACTION:R01304 go-plus.json UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity|PHB-O-glucosyltransferase activity|UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity|p-hydroxybenzoate glucosyltransferase activity|HBA glucosyltransferase activity|PHB glucosyltransferase activity|uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity|UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047250 CL:0002548 biolink:Cell fibroblast of cardiac tissue A fibroblast that is part of the heart. go-plus.json cardiac fibroblast http://purl.obolibrary.org/obo/CL_0002548 GO:0047259 biolink:MolecularActivity glucomannan 4-beta-mannosyltransferase activity Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP. MetaCyc:2.4.1.32-RXN|EC:2.4.1.32 go-plus.json glucomannan-synthase activity|GDP-man-beta-mannan mannosyltransferase activity|GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity|glucomannan 4-b-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0047259 GO:0047258 biolink:MolecularActivity sphingosine beta-galactosyltransferase activity Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP. MetaCyc:2.4.1.23-RXN|RHEA:19485|KEGG_REACTION:R01928|EC:2.4.1.23 go-plus.json UDPgalactose:sphingosine 1-beta-galactotransferase activity|psychosine-UDP galactosyltransferase activity|psychosine-uridine diphosphate galactosyltransferase activity|UDPgalactose:sphingosine O-galactosyl transferase activity|galactosyl-sphingosine transferase activity|uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity|UDP-galactose:sphingosine 1-beta-galactotransferase activity http://purl.obolibrary.org/obo/GO_0047258 GO:0047257 biolink:MolecularActivity diglucosyl diacylglycerol synthase activity Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol. RHEA:19165|MetaCyc:2.4.1.208-RXN|EC:2.4.1.208 go-plus.json monoglucosyl diacylglycerol (1->2) glucosyltransferase activity|diglucosyl diacylglycerol (DGlcDAG) synthase activity|MGlcDAG (1->2) glucosyltransferase activity|UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity|DGlcDAG synthase activity http://purl.obolibrary.org/obo/GO_0047257 GO:0047256 biolink:MolecularActivity lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP. RHEA:13905|MetaCyc:2.4.1.206-RXN|EC:2.4.1.206 go-plus.json uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity|LA2 synthase activity|beta1->3-N-acetylglucosaminyltransferase activity|lactosylceramide beta-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047256 GO:0047255 biolink:MolecularActivity galactogen 6-beta-galactosyltransferase activity Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP. MetaCyc:2.4.1.205-RXN|EC:2.4.1.205 go-plus.json UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity|beta-(1,6)-D-galactosyltransferase activity|1,6-D-galactosyltransferase activity|uridine diphosphogalactose-galactogen galactosyltransferase activity|UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity|galactogen 6beta-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047255 CL:0002540 biolink:Cell mesenchymal stem cell of the bone marrow A mesenchymal stem cell that is part of the bone marrow. go-plus.json http://purl.obolibrary.org/obo/CL_0002540 CL:0002541 biolink:Cell chorionic membrane mesenchymal stem cell A mesenchymal stem cell of the chorionic membrane. go-plus.json http://purl.obolibrary.org/obo/CL_0002541 CL:0002543 biolink:Cell vein endothelial cell An endothelial cell that is part of the vein. go-plus.json venous endothelial cell|endothelial cell of vein http://purl.obolibrary.org/obo/CL_0002543 CL:0002546 biolink:Cell embryonic blood vessel endothelial progenitor cell An endothelial progenitor cell that participates in angiogenesis during development. go-plus.json http://purl.obolibrary.org/obo/CL_0002546 GO:0072219 biolink:BiologicalProcess metanephric cortical collecting duct development The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0072219 GO:0072218 biolink:BiologicalProcess metanephric ascending thin limb development The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. go-plus.json http://purl.obolibrary.org/obo/GO_0072218 GO:0072217 biolink:BiologicalProcess negative regulation of metanephros development Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0072217 GO:0072216 biolink:BiologicalProcess positive regulation of metanephros development Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0072216 GO:0072215 biolink:BiologicalProcess regulation of metanephros development Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. go-plus.json http://purl.obolibrary.org/obo/GO_0072215 GO:0072214 biolink:BiologicalProcess metanephric cortex development The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072214 GO:0072213 biolink:BiologicalProcess metanephric capsule development The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go-plus.json http://purl.obolibrary.org/obo/GO_0072213 GO:0072212 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in metanephros development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072212 GO:0072211 biolink:BiologicalProcess metanephric pyramids development The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts. go-plus.json metanephric renal medulla development|metanephric kidney pyramid development|metanephric renal pyramid development|metanephric pyramid development http://purl.obolibrary.org/obo/GO_0072211 GO:0047265 biolink:MolecularActivity poly(glycerol-phosphate) alpha-glucosyltransferase activity Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP. RHEA:15845|EC:2.4.1.52|MetaCyc:2.4.1.52-RXN go-plus.json UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity|uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity|UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity|UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047265 GO:0047264 biolink:MolecularActivity heteroglycan alpha-mannosyltransferase activity Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP. EC:2.4.1.48 go-plus.json heteropolysaccharide alpha-mannosyltransferase activity|GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity|GDP mannose alpha-mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0047264 GO:0047263 biolink:MolecularActivity N-acylsphingosine galactosyltransferase activity Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP. EC:2.4.1.47|Reactome:R-HSA-6785933|MetaCyc:2.4.1.47-RXN|RHEA:13093 go-plus.json UDP-galactose:N-acylsphingosine D-galactosyltransferase activity|uridine diphosphogalactose-acylsphingosine galactosyltransferase activity|UDP galactose-N-acylsphingosine galactosyltransferase activity|UDPgalactose:N-acylsphingosine D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047263 GO:0047262 biolink:MolecularActivity polygalacturonate 4-alpha-galacturonosyltransferase activity Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP. EC:2.4.1.43|RHEA:13573|MetaCyc:2.4.1.43-RXN go-plus.json UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity|uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity|UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity http://purl.obolibrary.org/obo/GO_0047262 GO:0047261 biolink:MolecularActivity steroid N-acetylglucosaminyltransferase activity Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP. MetaCyc:2.4.1.39-RXN|KEGG_REACTION:R04451|RHEA:14153|EC:2.4.1.39 go-plus.json uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity|hydroxy steroid acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity|steroid acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047261 GO:1900008 biolink:BiologicalProcess obsolete negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. go-plus.json negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging http://purl.obolibrary.org/obo/GO_1900008 GO:0047260 biolink:MolecularActivity alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP. EC:2.4.1.36|RHEA:14605|MetaCyc:2.4.1.36-RXN go-plus.json GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|GDP-glucose-glucosephosphate glucosyltransferase activity|GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|GDPglucose-glucose-phosphate glucosyltransferase activity|trehalose phosphate synthase (GDP-forming) activity|guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047260 GO:0106202 biolink:MolecularActivity obsolete translocase activity acting on amino acids and peptides linked to a decarboxylation reaction OBSOLETE. Catalysis of the translocation of amno acids and peptides linked to a decarboxylation reaction. EC:7.4.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0106202 GO:1900007 biolink:BiologicalProcess obsolete regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging OBSOLETE. Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. go-plus.json regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing http://purl.obolibrary.org/obo/GO_1900007 GO:0106201 biolink:MolecularActivity obsolete translocase activity acting on amino acids and peptides linked to the hydrolysis of a diphosphate OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a diphosphate. EC:7.4.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0106201 GO:0106200 biolink:MolecularActivity obsolete translocase activity acting on amio acids and peptides linked to the hydrolysis of a nucleoside triphosphate OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a nucleoside triphosphate. EC:7.4.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0106200 GO:1900009 biolink:BiologicalProcess obsolete positive regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging OBSOLETE. Any process that activates or increases the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. go-plus.json up regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging|positive regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|up regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|up regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|up regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell aging http://purl.obolibrary.org/obo/GO_1900009 GO:1900004 biolink:BiologicalProcess negative regulation of serine-type endopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity. go-plus.json negative regulation of blood coagulation factor activity|down regulation of blood coagulation factor activity|down regulation of serine-type endopeptidase activity http://purl.obolibrary.org/obo/GO_1900004 CL:0002559 biolink:Cell hair follicle cell An animal cell that is part of a hair follicle. go-plus.json http://purl.obolibrary.org/obo/CL_0002559 GO:1900003 biolink:BiologicalProcess regulation of serine-type endopeptidase activity Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity. go-plus.json regulation of blood coagulation factor activity http://purl.obolibrary.org/obo/GO_1900003 GO:1900006 biolink:BiologicalProcess positive regulation of dendrite development Any process that activates or increases the frequency, rate or extent of dendrite development. go-plus.json up regulation of dendrite development http://purl.obolibrary.org/obo/GO_1900006 GO:1900005 biolink:BiologicalProcess positive regulation of serine-type endopeptidase activity Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity. go-plus.json positive regulation of blood coagulation factor activity|up regulation of serine-type endopeptidase activity|up regulation of blood coagulation factor activity http://purl.obolibrary.org/obo/GO_1900005 GO:0047269 biolink:MolecularActivity poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP. RHEA:21012|EC:2.4.1.70|MetaCyc:2.4.1.70-RXN go-plus.json UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity|UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047269 GO:1900000 biolink:BiologicalProcess regulation of anthocyanin catabolic process Any process that modulates the frequency, rate or extent of anthocyanin catabolic process. go-plus.json regulation of anthocyanin breakdown|regulation of anthocyanin catabolism|regulation of anthocyanin degradation http://purl.obolibrary.org/obo/GO_1900000 GO:0047268 biolink:MolecularActivity galactinol-raffinose galactosyltransferase activity Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol. EC:2.4.1.67|RHEA:20776|MetaCyc:2.4.1.67-RXN go-plus.json stachyose synthetase activity|alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047268 GO:1900002 biolink:BiologicalProcess positive regulation of anthocyanin catabolic process Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process. go-plus.json up regulation of anthocyanin degradation|positive regulation of anthocyanin degradation|up regulation of anthocyanin breakdown|positive regulation of anthocyanin breakdown|up regulation of anthocyanin catabolic process|positive regulation of anthocyanin catabolism|up regulation of anthocyanin catabolism http://purl.obolibrary.org/obo/GO_1900002 GO:0047267 biolink:MolecularActivity undecaprenyl-phosphate mannosyltransferase activity Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol. EC:2.4.1.54 go-plus.json GDP mannose-undecaprenyl phosphate mannosyltransferase activity|GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity|GDP-D-mannose:lipid phosphate transmannosylase activity|guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity http://purl.obolibrary.org/obo/GO_0047267 GO:1900001 biolink:BiologicalProcess negative regulation of anthocyanin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process. go-plus.json down regulation of anthocyanin breakdown|negative regulation of anthocyanin degradation|down regulation of anthocyanin catabolic process|negative regulation of anthocyanin breakdown|negative regulation of anthocyanin catabolism|down regulation of anthocyanin degradation|down regulation of anthocyanin catabolism http://purl.obolibrary.org/obo/GO_1900001 GO:0047266 biolink:MolecularActivity poly(ribitol-phosphate) beta-glucosyltransferase activity Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP. EC:2.4.1.53|RHEA:10068|MetaCyc:2.4.1.53-RXN go-plus.json uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity|UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity|UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP-D-glucose:polyribitol phosphate glucosyl transferase activity|UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP-D-glucose polyribitol phosphate glucosyl transferase activity http://purl.obolibrary.org/obo/GO_0047266 CL:0002553 biolink:Cell fibroblast of lung A fibroblast that is part of lung. go-plus.json http://purl.obolibrary.org/obo/CL_0002553 CL:0002555 biolink:Cell fibroblast of mammary gland A fibroblast that is part of the mammary gland. go-plus.json http://purl.obolibrary.org/obo/CL_0002555 CL:0002554 biolink:Cell fibroblast of lymphatic vessel A fibroblast of the lymphatic system. go-plus.json http://purl.obolibrary.org/obo/CL_0002554 GO:0072209 biolink:BiologicalProcess metanephric mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072209 CL:0002557 biolink:Cell fibroblast of pulmonary artery A fibroblast of pulmonary artery. go-plus.json http://purl.obolibrary.org/obo/CL_0002557 GO:0072208 biolink:BiologicalProcess metanephric smooth muscle tissue development The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072208 GO:0072207 biolink:BiologicalProcess metanephric epithelium development The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072207 GO:0072206 biolink:BiologicalProcess metanephric juxtaglomerular apparatus development The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. go-plus.json http://purl.obolibrary.org/obo/GO_0072206 GO:0072205 biolink:BiologicalProcess metanephric collecting duct development The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. go-plus.json http://purl.obolibrary.org/obo/GO_0072205 GO:0072204 biolink:BiologicalProcess cell-cell signaling involved in metanephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ. go-plus.json cell-cell signalling involved in metanephros development http://purl.obolibrary.org/obo/GO_0072204 GO:0072203 biolink:BiologicalProcess cell proliferation involved in metanephros development The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072203 GO:0072202 biolink:BiologicalProcess cell differentiation involved in metanephros development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072202 GO:0072201 biolink:BiologicalProcess negative regulation of mesenchymal cell proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json http://purl.obolibrary.org/obo/GO_0072201 GO:0072200 biolink:BiologicalProcess negative regulation of mesenchymal cell proliferation involved in ureter development Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. go-plus.json negative regulation of ureteral mesenchymal cell proliferation|negative regulation of ureter mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0072200 GO:0072232 biolink:BiologicalProcess metanephric proximal convoluted tubule segment 2 development The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride. go-plus.json metanephric S2 development http://purl.obolibrary.org/obo/GO_0072232 GO:0047276 biolink:MolecularActivity N-acetyllactosaminide 3-alpha-galactosyltransferase activity Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP. MetaCyc:2.4.1.151-RXN|EC:2.4.1.87|RHEA:13013 go-plus.json UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity|beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity|beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|N-acetyllactosaminide alpha-1,3-galactosyltransferase activity|glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity|alpha-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity|UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity|UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047276 GO:0106210 biolink:BiologicalProcess culmorin biosynthetic process The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris. go-plus.json culmorin anabolism|culmorin biosynthesis|culmorin synthesis|culmorin formation http://purl.obolibrary.org/obo/GO_0106210 GO:0047275 biolink:MolecularActivity glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP. MetaCyc:2.4.1.86-RXN|EC:2.4.1.86|RHEA:16045 go-plus.json UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity|UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|GalT-4|paragloboside synthase activity http://purl.obolibrary.org/obo/GO_0047275 GO:0072231 biolink:BiologicalProcess metanephric proximal convoluted tubule segment 1 development The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. go-plus.json metanephric S1 development http://purl.obolibrary.org/obo/GO_0072231 GO:0072230 biolink:BiologicalProcess metanephric proximal straight tubule development The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule. go-plus.json metanephric S3 development http://purl.obolibrary.org/obo/GO_0072230 GO:0047274 biolink:MolecularActivity galactinol-sucrose galactosyltransferase activity Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol. MetaCyc:2.4.1.82-RXN|EC:2.4.1.82|RHEA:20161 go-plus.json alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|galactinol:sucrose 6-galactosyl transferase activity|galactosyltransferase, galactinol-sucrose|raffinose synthase activity http://purl.obolibrary.org/obo/GO_0047274 GO:0047273 biolink:MolecularActivity galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide. MetaCyc:2.4.1.79-RXN|EC:2.4.1.79|Reactome:R-HSA-8878914|RHEA:22252 go-plus.json globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity|globoside synthase activity|galactosylgalactosylglucosylceramide beta-D- activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity|globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity|beta-3GalNAc-T1 activity|globoside synthetase activity|UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|beta3GalNAc-T1 http://purl.obolibrary.org/obo/GO_0047273 GO:0047272 biolink:MolecularActivity phosphopolyprenol glucosyltransferase activity Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP. MetaCyc:2.4.1.78-RXN|EC:2.4.1.78 go-plus.json uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity|UDP-glucose:phosphopolyprenol D-glucosyltransferase activity|UDPglucose:phosphopolyprenol D-glucosyltransferase activity|UDPglucose:polyprenol monophosphate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047272 GO:0106214 biolink:BiologicalProcess regulation of vesicle fusion with Golgi apparatus Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. go-plus.json http://purl.obolibrary.org/obo/GO_0106214 GO:1900019 biolink:BiologicalProcess regulation of protein kinase C activity Any process that modulates the frequency, rate or extent of protein kinase C activity. go-plus.json regulation of PKC|regulation of PKC activity http://purl.obolibrary.org/obo/GO_1900019 GO:1900018 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex. go-plus.json http://purl.obolibrary.org/obo/GO_1900018 GO:0106213 biolink:BiologicalProcess kinetochore disassembly involved in meiotic chromosome organization The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I. go-plus.json kinetochore disassembly from spindle pole body involved in chromosome organization involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0106213 GO:0047271 biolink:MolecularActivity glycosaminoglycan galactosyltransferase activity Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP. MetaCyc:2.4.1.74-RXN|EC:2.4.1.74 go-plus.json UDPgalactose:glycosaminoglycan D-galactosyltransferase activity|uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity|UDP-galactose:glycosaminoglycan D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047271 GO:0047270 biolink:MolecularActivity lipopolysaccharide glucosyltransferase II activity Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP. MetaCyc:2.4.1.73-RXN|EC:2.4.1.73 go-plus.json LPS glucosyltransferase II activity|UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity|uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity|UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047270 GO:0106212 biolink:BiologicalProcess centromere detachment from spindle pole body involved in meiotic chromosome organization The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I. go-plus.json centromere detachment from SPB involved in meiotic chromosome organization|centromere detachment from spindle pole body involved in chromosome organization involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0106212 GO:0106211 biolink:MolecularActivity inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate. RHEA:59500 go-plus.json 5-diphospho-myo-inositol 1,3,4,6-tetrakisphosphate diphosphatase activity|5-diphosphoinositol 1,3,4,6-tetrakisphosphate diphosphatase activity|5-PP-InsP4 activity http://purl.obolibrary.org/obo/GO_0106211 GO:0106218 biolink:BiologicalProcess galactosaminogalactan biosynthetic process The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN). go-plus.json galactosaminogalactan biosynthesis|galactosaminogalactan anabolism|GAG biosynthetic process|galactosaminogalactan synthesis|galactosaminogalactan formation http://purl.obolibrary.org/obo/GO_0106218 GO:1900015 biolink:BiologicalProcess regulation of cytokine production involved in inflammatory response Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response. go-plus.json regulation of cytokine production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_1900015 CL:0002525 biolink:Cell metanephric glomerular visceral epithelial cell A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros. go-plus.json http://purl.obolibrary.org/obo/CL_0002525 GO:1900014 biolink:BiologicalProcess obsolete cellular response to calcium ion involved in chemotaxis to cAMP OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. go-plus.json cellular response to calcium ion of chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to Ca2+ ion of chemotaxis to 3',5' cAMP|cellular response to calcium ion involved in chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to cyclic AMP|cellular response to calcium ion of chemotaxis to 3',5' cAMP|cellular response to Ca2+ ion of chemotaxis to 3',5'-cAMP|cellular response to Ca2+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to Ca2+ ion of chemotaxis to cyclic AMP|cellular response to Ca2+ ion of chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to 3',5'-cAMP http://purl.obolibrary.org/obo/GO_1900014 GO:0106217 biolink:BiologicalProcess tRNA C3-cytosine methylation The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0106217 GO:1900017 biolink:BiologicalProcess positive regulation of cytokine production involved in inflammatory response Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response. go-plus.json positive regulation of cytokine production involved in acute inflammatory response|up regulation of cytokine production involved in inflammatory response|up regulation of cytokine production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_1900017 GO:0106216 biolink:BiologicalProcess positive regulation of vesicle fusion with Golgi apparatus Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. go-plus.json http://purl.obolibrary.org/obo/GO_0106216 GO:1900016 biolink:BiologicalProcess negative regulation of cytokine production involved in inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response. go-plus.json negative regulation of cytokine production involved in acute inflammatory response|down regulation of cytokine production involved in inflammatory response|down regulation of cytokine production involved in acute inflammatory response http://purl.obolibrary.org/obo/GO_1900016 GO:0106215 biolink:BiologicalProcess negative regulation of vesicle fusion with Golgi apparatus Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. go-plus.json http://purl.obolibrary.org/obo/GO_0106215 GO:1900011 biolink:BiologicalProcess negative regulation of corticotropin-releasing hormone receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity. go-plus.json down regulation of adrenocorticotropin-releasing hormone receptor activity|down regulation of corticotropin-releasing factor receptor activity|negative regulation of CRH receptor activity|negative regulation of CRF receptor activity|negative regulation of adrenocorticotropin-releasing hormone receptor activity|down regulation of corticotropin-releasing hormone receptor activity|negative regulation of corticotropin-releasing factor receptor activity|down regulation of CRH receptor activity|down regulation of CRF receptor activity http://purl.obolibrary.org/obo/GO_1900011 GO:1900010 biolink:BiologicalProcess regulation of corticotropin-releasing hormone receptor activity Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity. go-plus.json regulation of corticotropin-releasing factor receptor activity|regulation of adrenocorticotropin-releasing hormone receptor activity|regulation of CRH receptor activity|regulation of CRF receptor activity http://purl.obolibrary.org/obo/GO_1900010 GO:0047279 biolink:MolecularActivity sn-glycerol-3-phosphate 1-galactosyltransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP. MetaCyc:2.4.1.96-RXN|KEGG_REACTION:R00854|EC:2.4.1.96|RHEA:20341 go-plus.json uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity|glycerol 3-phosphate 1alpha-galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity|UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity|UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|isofloridoside-phosphate synthase activity http://purl.obolibrary.org/obo/GO_0047279 GO:0047278 biolink:MolecularActivity bilirubin-glucuronoside glucuronosyltransferase activity Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside. MetaCyc:2.4.1.95-RXN|RHEA:16885|KEGG_REACTION:R00062 go-plus.json bilirubin monoglucuronide transglucuronidase activity|bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity|bilirubin glucuronoside glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0047278 GO:1900013 biolink:BiologicalProcess obsolete cellular response to potassium ion involved in chemotaxis to cAMP OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. go-plus.json cellular response to potassium of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to 3',5' cAMP|cellular response to potassium of chemotaxis to 3',5' cAMP|cellular response to potassium ion involved in chemotaxis to cAMP|cellular response to K+ ion of chemotaxis to 3',5'-cAMP|cellular response to K+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to K+ ion of chemotaxis to cyclic AMP|cellular response to K+ ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to 3',5'-cAMP|cellular response to potassium of chemotaxis to 3',5'-cAMP|cellular response to potassium ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to K+ ion of chemotaxis to 3',5' cAMP|cellular response to potassium of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium ion of chemotaxis to cyclic AMP|cellular response to potassium of chemotaxis to cyclic AMP http://purl.obolibrary.org/obo/GO_1900013 GO:0047277 biolink:MolecularActivity globoside alpha-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP. MetaCyc:2.4.1.88-RXN|EC:2.4.1.88|RHEA:22164 go-plus.json globoside acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity|Forssman synthase activity|forssman synthase activity http://purl.obolibrary.org/obo/GO_0047277 GO:1900012 biolink:BiologicalProcess positive regulation of corticotropin-releasing hormone receptor activity Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity. go-plus.json up regulation of CRH receptor activity|up regulation of CRF receptor activity|positive regulation of CRH receptor activity|positive regulation of CRF receptor activity|up regulation of adrenocorticotropin-releasing hormone receptor activity|positive regulation of adrenocorticotropin-releasing hormone receptor activity|up regulation of corticotropin-releasing hormone receptor activity|positive regulation of corticotropin-releasing factor receptor activity|up regulation of corticotropin-releasing factor receptor activity http://purl.obolibrary.org/obo/GO_1900012 GO:0106219 biolink:MolecularActivity zinc ion sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of zinc. go-plus.json http://purl.obolibrary.org/obo/GO_0106219 GO:1900020 biolink:BiologicalProcess positive regulation of protein kinase C activity Any process that activates or increases the frequency, rate or extent of protein kinase C activity. go-plus.json positive regulation of PKC activity|up regulation of PKC activity|up regulation of PKC|positive regulation of PKC http://purl.obolibrary.org/obo/GO_1900020 CL:0002520 biolink:Cell nephrocyte An insect excretory cell that regulates haemolymph composition by filtration and filtrate endocytosis. go-plus.json http://purl.obolibrary.org/obo/CL_0002520 CL:0002522 biolink:Cell renal filtration cell A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both. go-plus.json http://purl.obolibrary.org/obo/CL_0002522 CL:0002524 biolink:Cell disseminated nephrocyte A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues. go-plus.json http://purl.obolibrary.org/obo/CL_0002524 CL:0002523 biolink:Cell mesonephric glomerular visceral epithelial cell A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros go-plus.json http://purl.obolibrary.org/obo/CL_0002523 GO:0072239 biolink:BiologicalProcess metanephric glomerulus vasculature development The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. go-plus.json glomerulus capillary development http://purl.obolibrary.org/obo/GO_0072239 GO:0072238 biolink:BiologicalProcess metanephric long nephron development The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros. go-plus.json metanephric juxtamedullary nephron development http://purl.obolibrary.org/obo/GO_0072238 GO:0072237 biolink:BiologicalProcess metanephric proximal tubule development The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0072237 GO:0072236 biolink:BiologicalProcess metanephric loop of Henle development The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. go-plus.json metanephric intermediate tubule development http://purl.obolibrary.org/obo/GO_0072236 GO:0072235 biolink:BiologicalProcess metanephric distal tubule development The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072235 GO:0072234 biolink:BiologicalProcess metanephric nephron tubule development The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072234 GO:0072233 biolink:BiologicalProcess metanephric thick ascending limb development The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. go-plus.json metanephric TAL development http://purl.obolibrary.org/obo/GO_0072233 GO:0072221 biolink:BiologicalProcess metanephric distal convoluted tubule development The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. go-plus.json http://purl.obolibrary.org/obo/GO_0072221 GO:0047287 biolink:MolecularActivity lactosylceramide alpha-2,6-N-sialyltransferase activity Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP. RHEA:21552|MetaCyc:2.4.99.11-RXN|EC:2.4.99.11 go-plus.json CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|CMP-sialic acid:lactosylceramide sialyltransferase activity|CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity http://purl.obolibrary.org/obo/GO_0047287 GO:0047286 biolink:MolecularActivity NAD+-diphthamide ADP-ribosyltransferase activity Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide. EC:2.4.2.36|RHEA:11820|Reactome:R-HSA-5336421|MetaCyc:RXN-11372 go-plus.json NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity|mono(ADP-ribosyl)transferase activity|ADP-ribosyltransferase activity|NAD-diphthamide ADP-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0047286 GO:0072220 biolink:BiologicalProcess metanephric descending thin limb development The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle. go-plus.json http://purl.obolibrary.org/obo/GO_0072220 GO:0106220 biolink:BiologicalProcess pyocyanine biosynthetic process The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. go-plus.json pyocyanin biosynthetic process http://purl.obolibrary.org/obo/GO_0106220 GO:0047285 biolink:MolecularActivity flavonol-3-O-glycoside xylosyltransferase activity Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP. EC:2.4.2.35|RHEA:19701|MetaCyc:2.4.2.35-RXN go-plus.json UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0047285 GO:0047284 biolink:MolecularActivity dolichyl-xylosyl-phosphate-protein xylosyltransferase activity Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein. EC:2.4.2.33|MetaCyc:2.4.2.33-RXN|RHEA:18361 go-plus.json dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0047284 GO:0047283 biolink:MolecularActivity dolichyl-phosphate D-xylosyltransferase activity Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP. EC:2.4.2.32|RHEA:15361|MetaCyc:2.4.2.32-RXN go-plus.json UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity http://purl.obolibrary.org/obo/GO_0047283 GO:0106225 biolink:BiologicalProcess peptidyl-lysine 2-hydroxyisobutyrylation The 2-hydroxyisobutyrylation of a lysine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0106225 GO:0047282 biolink:MolecularActivity dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+). KEGG_REACTION:R04222|MetaCyc:2.4.2.27-RXN|RHEA:24392|EC:2.4.2.27 go-plus.json dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity|dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity|thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity http://purl.obolibrary.org/obo/GO_0047282 GO:1900029 biolink:BiologicalProcess positive regulation of ruffle assembly Any process that activates or increases the frequency, rate or extent of ruffle assembly. go-plus.json up regulation of membrane ruffle formation|positive regulation of membrane ruffle formation|up regulation of membrane ruffling|up regulation of ruffle assembly|positive regulation of membrane ruffling http://purl.obolibrary.org/obo/GO_1900029 GO:0106223 biolink:MolecularActivity germacrene A hydroxylase activity Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. EC:1.14.14.95|RHEA:30303|MetaCyc:RXN-12449 go-plus.json germacrene A alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0106223 GO:0047281 biolink:MolecularActivity dioxotetrahydropyrimidine phosphoribosyltransferase activity Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine. EC:2.4.2.20|RHEA:10232|MetaCyc:2.4.2.20-RXN go-plus.json dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity|dioxotetrahydropyrimidine phosphoribosyl transferase activity|2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity http://purl.obolibrary.org/obo/GO_0047281 GO:0047280 biolink:MolecularActivity nicotinamide phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide. EC:2.4.2.12|RHEA:16149|KEGG_REACTION:R01271|Reactome:R-HSA-197250|MetaCyc:2.4.2.12-RXN go-plus.json nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinamide mononucleotide synthetase activity|nicotinamide mononucleotide pyrophosphorylase activity|NMN pyrophosphorylase activity|NMN diphosphorylase activity|NMN synthetase activity http://purl.obolibrary.org/obo/GO_0047280 GO:0106222 biolink:MolecularActivity long noncoding RNA binding Binding to a long noncoding RNA (lncRNA). go-plus.json lncRNA binding http://purl.obolibrary.org/obo/GO_0106222 GO:1900026 biolink:BiologicalProcess positive regulation of substrate adhesion-dependent cell spreading Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading. go-plus.json positive regulation of substrate adhesion dependent cell spreading|up regulation of substrate adhesion-dependent cell spreading|up regulation of cell spreading during cell substrate adhesion|positive regulation of cell spreading during cell substrate adhesion|up regulation of substrate adhesion dependent cell spreading http://purl.obolibrary.org/obo/GO_1900026 GO:0106229 biolink:MolecularActivity histone glutaryltransferase activity Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone. go-plus.json http://purl.obolibrary.org/obo/GO_0106229 GO:1900025 biolink:BiologicalProcess negative regulation of substrate adhesion-dependent cell spreading Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading. go-plus.json negative regulation of cell spreading during cell substrate adhesion|negative regulation of substrate adhesion dependent cell spreading|down regulation of substrate adhesion-dependent cell spreading|down regulation of cell spreading during cell substrate adhesion|down regulation of substrate adhesion dependent cell spreading http://purl.obolibrary.org/obo/GO_1900025 GO:0106228 biolink:MolecularActivity peptide glutaryltransferase activity Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein]. RHEA:18009 go-plus.json http://purl.obolibrary.org/obo/GO_0106228 GO:0106227 biolink:BiologicalProcess peptidyl-lysine glutarylation The glutarylation of a lysine residue in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0106227 GO:1900028 biolink:BiologicalProcess negative regulation of ruffle assembly Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly. go-plus.json negative regulation of membrane ruffle formation|down regulation of membrane ruffling|down regulation of ruffle assembly|down regulation of membrane ruffle formation|negative regulation of membrane ruffling http://purl.obolibrary.org/obo/GO_1900028 CL:0002539 biolink:Cell aortic smooth muscle cell A smooth muscle cell of the aorta. go-plus.json http://purl.obolibrary.org/obo/CL_0002539 GO:1900027 biolink:BiologicalProcess regulation of ruffle assembly Any process that modulates the frequency, rate or extent of ruffle assembly. go-plus.json regulation of membrane ruffling|regulation of membrane ruffle formation http://purl.obolibrary.org/obo/GO_1900027 GO:0106226 biolink:MolecularActivity peptide 2-hydroxyisobutyryltransferase activity Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide. RHEA:24180 go-plus.json http://purl.obolibrary.org/obo/GO_0106226 GO:1900022 biolink:BiologicalProcess regulation of D-erythro-sphingosine kinase activity Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity. go-plus.json regulation of sphingosine kinase activity http://purl.obolibrary.org/obo/GO_1900022 GO:0047289 biolink:MolecularActivity galactosyldiacylglycerol alpha-2,3-sialyltransferase activity Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+). KEGG_REACTION:R03468|RHEA:11664|MetaCyc:2.4.99.5-RXN|EC:2.4.99.5 go-plus.json CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity http://purl.obolibrary.org/obo/GO_0047289 GO:1900024 biolink:BiologicalProcess regulation of substrate adhesion-dependent cell spreading Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading. go-plus.json regulation of cell spreading during cell substrate adhesion|regulation of substrate adhesion dependent cell spreading http://purl.obolibrary.org/obo/GO_1900024 GO:1900023 biolink:BiologicalProcess positive regulation of D-erythro-sphingosine kinase activity Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity. go-plus.json up regulation of D-erythro-sphingosine kinase activity|up regulation of sphingosine kinase activity|positive regulation of sphingosine kinase activity http://purl.obolibrary.org/obo/GO_1900023 GO:0047288 biolink:MolecularActivity monosialoganglioside sialyltransferase activity Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP. MetaCyc:2.4.99.2-RXN|RHEA:18021|EC:2.4.99.2 go-plus.json CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity http://purl.obolibrary.org/obo/GO_0047288 GO:1900031 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling. go-plus.json regulation of transcription from RNA polymerase II promoter of calcium signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|regulation of global transcription from Pol II promoter of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signaling|global transcription regulation from Pol II promoter of calcium ion signaling|global transcription regulation from Pol II promoter of calcium-mediated signalling|global transcription regulation from Pol II promoter of calcium signalling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|regulation of transcription from Pol II promoter of calcium signalling|global transcription regulation from Pol II promoter of calcium signaling|regulation of transcription from RNA polymerase II promoter, global of calcium ion signaling|global transcription regulation from Pol II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signalling|regulation of global transcription from Pol II promoter of calcium-mediated signalling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of global transcription from Pol II promoter of calcium ion signaling|regulation of transcription from RNA polymerase II promoter of calcium signalling|regulation of transcription from Pol II promoter of calcium ion signaling|regulation of transcription from Pol II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter, global of calcium signaling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter of calcium ion signaling|regulation of transcription from Pol II promoter of calcium-mediated signaling|regulation of global transcription from Pol II promoter of calcium signaling|regulation of global transcription from Pol II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium signalling|regulation of transcription from Pol II promoter of calcium signaling http://purl.obolibrary.org/obo/GO_1900031 GO:1900030 biolink:BiologicalProcess regulation of pectin biosynthetic process Any process that modulates the frequency, rate or extent of pectin biosynthetic process. go-plus.json regulation of pectin formation|regulation of pectin biosynthesis|regulation of pectin anabolism|regulation of pectin synthesis http://purl.obolibrary.org/obo/GO_1900030 CL:0002533 biolink:Cell immature CD16-positive myeloid dendritic cell An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low. go-plus.json http://purl.obolibrary.org/obo/CL_0002533 CL:0002532 biolink:Cell CD16-positive myeloid dendritic cell A myeloid dendritic cell found in the blood that is CD16-positive. go-plus.json CD16-mDC|CD16+ mDC http://purl.obolibrary.org/obo/CL_0002532 CL:0002535 biolink:Cell epithelial cell of cervix An epithelial cell of the cervix. go-plus.json epithelial cell of neck of uterus|cervical canal of uterus epithelial cell|cervix epithelial cell|neck of uterus epithelial cell|epithelial cell of cervix of uterus|epithelial cell of cervical canal|epithelial cell of uterine cervix|cervix of uterus epithelial cell|cervical canal epithelial cell|epithelial cell of cervical canal of uterus|uterine cervix epithelial cell http://purl.obolibrary.org/obo/CL_0002535 CL:0002534 biolink:Cell mature CD16-positive myeloid dendritic cell A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. go-plus.json http://purl.obolibrary.org/obo/CL_0002534 GO:0047290 biolink:MolecularActivity (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP. EC:2.4.99.7|RHEA:53896|KEGG_REACTION:R04635|MetaCyc:2.4.99.7-RXN|Reactome:R-HSA-981809 go-plus.json (alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity|alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity|NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity|ST6GALNAC activity|sialyltransferase 7D activity|sialyltransferase 3C activity|SIAT7 http://purl.obolibrary.org/obo/GO_0047290 GO:0072229 biolink:BiologicalProcess metanephric proximal convoluted tubule development The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0072229 CHEBI:156548 biolink:ChemicalSubstance kainate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_156548 GO:0072228 biolink:BiologicalProcess metanephric prebend segment development The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. go-plus.json http://purl.obolibrary.org/obo/GO_0072228 GO:0072227 biolink:BiologicalProcess metanephric macula densa development The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072227 GO:0072226 biolink:BiologicalProcess metanephric long descending thin limb bend development The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072226 GO:0072225 biolink:BiologicalProcess metanephric late distal convoluted tubule development The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. go-plus.json http://purl.obolibrary.org/obo/GO_0072225 GO:0072224 biolink:BiologicalProcess metanephric glomerulus development The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. go-plus.json metanephric glomerular development http://purl.obolibrary.org/obo/GO_0072224 GO:0072223 biolink:BiologicalProcess metanephric glomerular mesangium development The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072223 GO:0072222 biolink:BiologicalProcess metanephric early distal convoluted tubule development The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive. go-plus.json http://purl.obolibrary.org/obo/GO_0072222 GO:0047298 biolink:MolecularActivity (S)-3-amino-2-methylpropionate transaminase activity Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate. MetaCyc:2.6.1.22-RXN|EC:2.6.1.22|RHEA:13993|KEGG_REACTION:R04188 go-plus.json L-3-aminoisobutyrate aminotransferase activity|beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity|L-3-aminoisobutyric aminotransferase activity|L-3-aminoisobutyrate transaminase activity|(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity|beta-aminobutyric transaminase activity|(S)-3-amino-2-methylpropionate aminotransferase activity|L-AIBAT activity http://purl.obolibrary.org/obo/GO_0047298 GO:0072254 biolink:BiologicalProcess metanephric glomerular mesangial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072254 UBERON:0036291 biolink:AnatomicalEntity myocardium of anterior wall of right ventricle go-plus.json http://purl.obolibrary.org/obo/UBERON_0036291 GO:0072253 biolink:BiologicalProcess metanephric juxtaglomerulus cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072253 GO:0047297 biolink:MolecularActivity asparagine-oxo-acid transaminase activity Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate. EC:2.6.1.14|RHEA:19813|MetaCyc:2.6.1.14-RXN go-plus.json asparagine--oxo-acid aminotransferase activity|L-asparagine:2-oxo-acid aminotransferase activity|asparagine-oxo-acid aminotransferase activity|asparagine-keto acid aminotransferase activity http://purl.obolibrary.org/obo/GO_0047297 UBERON:0036290 biolink:AnatomicalEntity myocardium of anterior wall of left ventricle go-plus.json http://purl.obolibrary.org/obo/UBERON_0036290 GO:0047296 biolink:MolecularActivity homospermidine synthase activity Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine. MetaCyc:2.5.1.44-RXN|EC:2.5.1.44|RHEA:18645 go-plus.json putrescine:putrescine 4-aminobutyltransferase (ammonia-forming) http://purl.obolibrary.org/obo/GO_0047296 GO:0072252 biolink:BiologicalProcess metanephric juxtaglomerulus cell development The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072252 GO:0047295 biolink:MolecularActivity geranylgeranylglycerol-phosphate geranylgeranyltransferase activity Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate. MetaCyc:2.5.1.42-RXN|EC:2.5.1.42|RHEA:18109|KEGG_REACTION:R04520 go-plus.json geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity|geranylgeranyltransferase II|geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity http://purl.obolibrary.org/obo/GO_0047295 GO:0072251 biolink:BiologicalProcess metanephric juxtaglomerulus cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072251 GO:0072250 biolink:BiologicalProcess metanephric glomerular visceral epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. go-plus.json metanephric podocyte cell fate commitment http://purl.obolibrary.org/obo/GO_0072250 GO:0047294 biolink:MolecularActivity phosphoglycerol geranylgeranyltransferase activity Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate. MetaCyc:2.5.1.41-RXN|RHEA:23404|EC:2.5.1.41|KEGG_REACTION:R04158 go-plus.json geranylgeranyl-transferase activity|glycerol phosphate geranylgeranyltransferase activity|geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity http://purl.obolibrary.org/obo/GO_0047294 UBERON:0036295 biolink:AnatomicalEntity renal pelvis/ureter The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. go-plus.json renal pelvis plus ureter|renal pelvis and ureter http://purl.obolibrary.org/obo/UBERON_0036295 GO:0047293 biolink:MolecularActivity 4-hydroxybenzoate nonaprenyltransferase activity Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate. EC:2.5.1.39|RHEA:17709|MetaCyc:2.5.1.39-RXN go-plus.json p-hydroxybenzoic acid-polyprenyl transferase activity|solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity|4-hydroxybenzoate transferase activity|p-hydroxybenzoate dimethylallyltransferase activity|nonaprenyl-4-hydroxybenzoate transferase activity|p-hydroxybenzoic-polyprenyl transferase activity|p-hydroxybenzoate polyprenyltransferase activity http://purl.obolibrary.org/obo/GO_0047293 UBERON:0036294 biolink:AnatomicalEntity mucosa of lip A mucosa that is part of a lip region [Automatically generated definition]. go-plus.json labial mucosa http://purl.obolibrary.org/obo/UBERON_0036294 GO:0047292 biolink:MolecularActivity trihydroxypterocarpan dimethylallyltransferase activity Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate. EC:2.5.1.36|MetaCyc:2.5.1.36-RXN go-plus.json dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity|dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity http://purl.obolibrary.org/obo/GO_0047292 GO:0047291 biolink:MolecularActivity lactosylceramide alpha-2,3-sialyltransferase activity Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3. EC:2.4.99.9|MetaCyc:2.4.99.9-RXN|RHEA:18417 go-plus.json ganglioside GM3 synthetase activity|CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity|GM3 synthase activity|CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity|CMP-sialic acid:lactosylceramide-sialyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|ganglioside GM3 synthase activity|cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|SAT 1|GM3 synthetase activity http://purl.obolibrary.org/obo/GO_0047291 CL:0002504 biolink:Cell enteric smooth muscle cell A smooth muscle cell of the intestine. go-plus.json intestinal smooth muscle cell http://purl.obolibrary.org/obo/CL_0002504 GO:1900037 biolink:BiologicalProcess regulation of cellular response to hypoxia Any process that modulates the frequency, rate or extent of cellular response to hypoxia. go-plus.json regulation of cellular response to hypoxic stress|regulation of cellular response to lowered oxygen tension http://purl.obolibrary.org/obo/GO_1900037 GO:1900036 biolink:BiologicalProcess positive regulation of cellular response to heat Any process that activates or increases the frequency, rate or extent of cellular response to heat. go-plus.json up regulation of cellular response to heat|up-regulation of cellular response to heat stress|activation of cellular response to heat|activation of cellular response to heat stress|up-regulation of cellular response to heat|positive regulation of cellular response to heat stress|up regulation of cellular response to heat stress|upregulation of cellular response to heat|upregulation of cellular response to heat stress http://purl.obolibrary.org/obo/GO_1900036 CHEBI:132569 biolink:ChemicalSubstance O-(S-[2R,4R,6R,8R]-2,4,6,8-tetramethyl-very-long-chain fatty acyl-pantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132569 chebi_ph7_3 GO:1900039 biolink:BiologicalProcess positive regulation of cellular response to hypoxia Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia. go-plus.json positive regulation of cellular response to hypoxic stress|positive regulation of cellular response to lowered oxygen tension|activation of cellular response to lowered oxygen tension|activation of cellular response to hypoxic stress|upregulation of cellular response to hypoxia|up-regulation of cellular response to lowered oxygen tension|up-regulation of cellular response to hypoxic stress|up-regulation of cellular response to hypoxia|upregulation of cellular response to lowered oxygen tension|upregulation of cellular response to hypoxic stress|activation of cellular response to hypoxia|up regulation of cellular response to hypoxia|up regulation of cellular response to hypoxic stress|up regulation of cellular response to lowered oxygen tension http://purl.obolibrary.org/obo/GO_1900039 GO:1900038 biolink:BiologicalProcess negative regulation of cellular response to hypoxia Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia. go-plus.json downregulation of cellular response to hypoxia|negative regulation of cellular response to lowered oxygen tension|down regulation of cellular response to hypoxia|down-regulation of cellular response to lowered oxygen tension|negative regulation of cellular response to hypoxic stress|down-regulation of cellular response to hypoxic stress|inhibition of cellular response to hypoxia|inhibition of cellular response to lowered oxygen tension|inhibition of cellular response to hypoxic stress|down-regulation of cellular response to hypoxia|down regulation of cellular response to hypoxic stress|down regulation of cellular response to lowered oxygen tension|downregulation of cellular response to lowered oxygen tension|downregulation of cellular response to hypoxic stress http://purl.obolibrary.org/obo/GO_1900038 GO:1900033 biolink:BiologicalProcess negative regulation of trichome patterning Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning. go-plus.json down regulation of trichome distribution|downregulation of trichome pattern biosynthesis|downregulation of trichome spacing|inhibition of trichome pattern specification|downregulation of trichome distribution|downregulation of trichome pattern formation|inhibition of trichome patterning|down regulation of trichome spacing|down regulation of trichome pattern formation|negative regulation of trichome pattern biosynthesis|down-regulation of trichome pattern biosynthesis|down regulation of trichome patterning|negative regulation of trichome distribution|inhibition of trichome spacing|down-regulation of trichome distribution|down-regulation of trichome pattern specification|negative regulation of trichome pattern specification|inhibition of trichome pattern formation|downregulation of trichome patterning|inhibition of trichome pattern biosynthesis|downregulation of trichome pattern specification|down-regulation of trichome spacing|negative regulation of trichome spacing|down-regulation of trichome patterning|inhibition of trichome distribution|down regulation of trichome pattern specification|negative regulation of trichome pattern formation|down-regulation of trichome pattern formation|down regulation of trichome pattern biosynthesis http://purl.obolibrary.org/obo/GO_1900033 CL:0002507 biolink:Cell langerin-positive lymph node dendritic cell A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002507 GO:1900032 biolink:BiologicalProcess regulation of trichome patterning Any process that modulates the frequency, rate or extent of trichome patterning. go-plus.json regulation of trichome distribution|regulation of trichome spacing|regulation of trichome pattern formation|regulation of trichome pattern specification|regulation of trichome pattern biosynthesis http://purl.obolibrary.org/obo/GO_1900032 GO:1900035 biolink:BiologicalProcess negative regulation of cellular response to heat Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat. go-plus.json downregulation of cellular response to heat|inhibition of cellular response to heat stress|down-regulation of cellular response to heat|down-regulation of cellular response to heat stress|negative regulation of cellular response to heat stress|downregulation of cellular response to heat stress|inhibition of cellular response to heat|down regulation of cellular response to heat stress|down regulation of cellular response to heat http://purl.obolibrary.org/obo/GO_1900035 GO:0047299 biolink:MolecularActivity tryptophan-phenylpyruvate transaminase activity Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine. EC:2.6.1.28|KEGG_REACTION:R01376|RHEA:13741|MetaCyc:2.6.1.28-RXN go-plus.json L-tryptophan:phenylpyruvate aminotransferase activity|tryptophan-phenylpyruvate aminotransferase activity|tryptophan--phenylpyruvate aminotransferase activity|L-tryptophan-alpha-ketoisocaproate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047299 GO:1900034 biolink:BiologicalProcess regulation of cellular response to heat Any process that modulates the frequency, rate or extent of cellular response to heat. go-plus.json regulation of cellular response to heat stress http://purl.obolibrary.org/obo/GO_1900034 CHEBI:132562 biolink:ChemicalSubstance lysophosphatidylethanolamine O-34:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132562 GO:1900040 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900040 CHEBI:132561 biolink:ChemicalSubstance PE(O-18:1/0:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132561 GO:1900042 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900042 CHEBI:132564 biolink:ChemicalSubstance phosphatidic acid 14:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132564 GO:1900041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900041 CHEBI:132565 biolink:ChemicalSubstance phosphatidic acid 16:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132565 CHEBI:132568 biolink:ChemicalSubstance phosphatidic acid 37:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132568 CHEBI:132567 biolink:ChemicalSubstance phosphatidic acid 18:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132567 CHEBI:156536 biolink:ChemicalSubstance oligoglycosyl-(1->4)-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_156536 chebi_ph7_3 GO:0072259 biolink:BiologicalProcess metanephric interstitial fibroblast development The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure. go-plus.json metanephros interstitial cell development http://purl.obolibrary.org/obo/GO_0072259 GO:0072258 biolink:BiologicalProcess metanephric interstitial fibroblast differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state. go-plus.json metanephros interstitial cell differentiation http://purl.obolibrary.org/obo/GO_0072258 GO:0072257 biolink:BiologicalProcess metanephric nephron tubule epithelial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0072257 GO:0072256 biolink:BiologicalProcess metanephric glomerular mesangial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0072256 GO:0072255 biolink:BiologicalProcess metanephric glomerular mesangial cell development The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0072255 GO:0072243 biolink:BiologicalProcess metanephric nephron epithelium development The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072243 GO:0072242 biolink:BiologicalProcess metanephric DCT cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell. go-plus.json metanephric distal convoluted tubule cell fate commitment http://purl.obolibrary.org/obo/GO_0072242 GO:0072241 biolink:BiologicalProcess metanephric DCT cell development The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure. go-plus.json metanephric distal convoluted tubule cell development http://purl.obolibrary.org/obo/GO_0072241 GO:0072240 biolink:BiologicalProcess metanephric DCT cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state. go-plus.json metanephric distal convoluted tubule cell differentiation http://purl.obolibrary.org/obo/GO_0072240 GO:1900048 biolink:BiologicalProcess positive regulation of hemostasis Any process that activates or increases the frequency, rate or extent of hemostasis. go-plus.json up-regulation of hemostasis|activation of hemostasis|up regulation of hemostasis|upregulation of hemostasis http://purl.obolibrary.org/obo/GO_1900048 GO:1900047 biolink:BiologicalProcess negative regulation of hemostasis Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. go-plus.json down-regulation of hemostasis|downregulation of hemostasis|down regulation of hemostasis|inhibition of hemostasis http://purl.obolibrary.org/obo/GO_1900047 GO:1900049 biolink:BiologicalProcess regulation of histone exchange Any process that modulates the frequency, rate or extent of histone exchange. go-plus.json regulation of histone replacement|regulation of histone chaperone|regulation of histone displacement http://purl.obolibrary.org/obo/GO_1900049 GO:1900044 biolink:BiologicalProcess regulation of protein K63-linked ubiquitination Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination. go-plus.json regulation of protein K63-linked polyubiquitination http://purl.obolibrary.org/obo/GO_1900044 GO:1900043 biolink:BiologicalProcess obsolete leptin-mediated signaling pathway involved in negative regulation of appetite OBSOLETE. Any leptin-mediated signaling pathway that is involved in negative regulation of appetite. go-plus.json leptin-mediated signaling pathway of appetite suppression|adipocytokine signaling pathway of down regulation of appetite|leptin-mediated signaling pathway of down-regulation of appetite|leptin-mediated signaling pathway of negative regulation of appetite|leptin-mediated signalling pathway of downregulation of appetite|leptin-mediated signaling pathway of inhibition of appetite|leptin-mediated signalling pathway of negative regulation of hunger|adipocytokine signaling pathway of negative regulation of hunger|leptin-mediated signaling pathway involved in negative regulation of appetite|adipocytokine signaling pathway of downregulation of appetite|leptin-mediated signalling pathway of down-regulation of appetite|leptin-mediated signalling pathway of inhibition of appetite|adipocytokine signaling pathway of appetite suppression|leptin-mediated signaling pathway of down regulation of appetite|leptin-mediated signalling pathway of appetite suppression|leptin-mediated signalling pathway of negative regulation of appetite|adipocytokine signaling pathway of down-regulation of appetite|adipocytokine signaling pathway of negative regulation of appetite|adipocytokine signaling pathway of inhibition of appetite|leptin-mediated signaling pathway of negative regulation of hunger|leptin-mediated signalling pathway of down regulation of appetite|leptin-mediated signaling pathway of downregulation of appetite http://purl.obolibrary.org/obo/GO_1900043 CL:0002518 biolink:Cell kidney epithelial cell An epithelial cell of the kidney. go-plus.json http://purl.obolibrary.org/obo/CL_0002518 GO:1900046 biolink:BiologicalProcess regulation of hemostasis Any process that modulates the frequency, rate or extent of hemostasis. go-plus.json http://purl.obolibrary.org/obo/GO_1900046 GO:1900045 biolink:BiologicalProcess negative regulation of protein K63-linked ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination. go-plus.json downregulation of protein K63-linked polyubiquitination|inhibition of protein K63-linked ubiquitination|down-regulation of protein K63-linked polyubiquitination|negative regulation of protein K63-linked polyubiquitination|down regulation of protein K63-linked ubiquitination|downregulation of protein K63-linked ubiquitination|inhibition of protein K63-linked polyubiquitination|down-regulation of protein K63-linked ubiquitination|down regulation of protein K63-linked polyubiquitination http://purl.obolibrary.org/obo/GO_1900045 GO:1900051 biolink:BiologicalProcess positive regulation of histone exchange Any process that activates or increases the frequency, rate or extent of histone exchange. go-plus.json up regulation of histone chaperone|positive regulation of histone chaperone|upregulation of histone exchange|upregulation of histone replacement|activation of histone chaperone|up-regulation of histone exchange|up-regulation of histone chaperone|up regulation of histone replacement|positive regulation of histone replacement|activation of histone exchange|activation of histone replacement|upregulation of histone chaperone|up regulation of histone exchange|up-regulation of histone replacement http://purl.obolibrary.org/obo/GO_1900051 GO:1900050 biolink:BiologicalProcess negative regulation of histone exchange Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange. go-plus.json inhibition of histone replacement|down regulation of histone exchange|down-regulation of histone chaperone|negative regulation of histone chaperone|down regulation of histone replacement|inhibition of histone exchange|downregulation of histone replacement|inhibition of histone chaperone|down-regulation of histone exchange|down-regulation of histone replacement|negative regulation of histone replacement|down regulation of histone chaperone|downregulation of histone chaperone|downregulation of histone exchange http://purl.obolibrary.org/obo/GO_1900050 GO:1900053 biolink:BiologicalProcess negative regulation of retinoic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process. go-plus.json down regulation of retinoic acid anabolic process|down-regulation of retinoic acid biosynthetic process|inhibition of retinoic acid anabolic process|downregulation of retinoic acid biosynthetic process|down regulation of retinoic acid biosynthetic process|down-regulation of retinoic acid anabolic process|negative regulation of retinoic acid anabolic process|inhibition of retinoic acid biosynthetic process|downregulation of retinoic acid anabolic process http://purl.obolibrary.org/obo/GO_1900053 GO:1900052 biolink:BiologicalProcess regulation of retinoic acid biosynthetic process Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process. go-plus.json regulation of retinoic acid anabolic process http://purl.obolibrary.org/obo/GO_1900052 GO:0072249 biolink:BiologicalProcess metanephric glomerular visceral epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. go-plus.json metanephric podocyte development http://purl.obolibrary.org/obo/GO_0072249 GO:0072248 biolink:BiologicalProcess metanephric glomerular visceral epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. go-plus.json metanephric podocyte differentiation http://purl.obolibrary.org/obo/GO_0072248 GO:0072247 biolink:BiologicalProcess metanephric glomerular parietal epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. go-plus.json metanephric Bowman's capsule cell fate commitment http://purl.obolibrary.org/obo/GO_0072247 GO:0072246 biolink:BiologicalProcess metanephric glomerular parietal epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go-plus.json metanephric Bowman's capsule development http://purl.obolibrary.org/obo/GO_0072246 GO:0072245 biolink:BiologicalProcess metanephric glomerular parietal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0072245 CHEBI:132570 biolink:ChemicalSubstance O-(S-[2R,4R,6R]-2,4,6-trimethyl-very-long-chain fatty acyl-pantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132570 chebi_ph7_3 GO:0072244 biolink:BiologicalProcess metanephric glomerular epithelium development The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072244 GO:0072276 biolink:BiologicalProcess metanephric glomerulus vasculature morphogenesis The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. go-plus.json http://purl.obolibrary.org/obo/GO_0072276 GO:0072275 biolink:BiologicalProcess metanephric glomerulus morphogenesis The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072275 GO:0072274 biolink:BiologicalProcess metanephric glomerular basement membrane development The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration. go-plus.json http://purl.obolibrary.org/obo/GO_0072274 GO:0072273 biolink:BiologicalProcess metanephric nephron morphogenesis The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072273 GO:0072272 biolink:BiologicalProcess proximal/distal pattern formation involved in metanephric nephron development The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end). go-plus.json proximal-distal pattern formation involved in metanephric nephron development|proximal/distal metanephric nephron patterning http://purl.obolibrary.org/obo/GO_0072272 GO:0072271 biolink:BiologicalProcess metanephric short descending thin limb development The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology. go-plus.json http://purl.obolibrary.org/obo/GO_0072271 GO:0072270 biolink:BiologicalProcess metanephric short nephron development The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. go-plus.json http://purl.obolibrary.org/obo/GO_0072270 GO:1900059 biolink:BiologicalProcess positive regulation of sulfate assimilation Any process that activates or increases the frequency, rate or extent of sulfate assimilation. go-plus.json activation of sulfate assimilation|upregulation of sulphate assimilation|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulfate assimilation|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|up regulation of sulphate assimilation|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|positive regulation of sulphate assimilation|upregulation of sulfate assimilation|activation of sulphate assimilation|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up-regulation of sulphate assimilation|up-regulation of sulfate assimilation|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor http://purl.obolibrary.org/obo/GO_1900059 GO:1900058 biolink:BiologicalProcess regulation of sulfate assimilation Any process that modulates the frequency, rate or extent of sulfate assimilation. go-plus.json regulation of sulphate assimilation|regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor http://purl.obolibrary.org/obo/GO_1900058 GO:1900055 biolink:BiologicalProcess regulation of leaf senescence Any process that modulates the frequency, rate or extent of leaf senescence. go-plus.json http://purl.obolibrary.org/obo/GO_1900055 GO:1900054 biolink:BiologicalProcess positive regulation of retinoic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process. go-plus.json activation of retinoic acid biosynthetic process|upregulation of retinoic acid anabolic process|up regulation of retinoic acid biosynthetic process|up-regulation of retinoic acid anabolic process|upregulation of retinoic acid biosynthetic process|activation of retinoic acid anabolic process|positive regulation of retinoic acid anabolic process|up-regulation of retinoic acid biosynthetic process|up regulation of retinoic acid anabolic process http://purl.obolibrary.org/obo/GO_1900054 GO:1900057 biolink:BiologicalProcess positive regulation of leaf senescence Any process that activates or increases the frequency, rate or extent of leaf senescence. go-plus.json up regulation of leaf senescence|activation of leaf senescence|up-regulation of leaf senescence|upregulation of leaf senescence http://purl.obolibrary.org/obo/GO_1900057 GO:1900056 biolink:BiologicalProcess negative regulation of leaf senescence Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence. go-plus.json downregulation of leaf senescence|down-regulation of leaf senescence|inhibition of leaf senescence|down regulation of leaf senescence http://purl.obolibrary.org/obo/GO_1900056 GO:1900062 biolink:BiologicalProcess obsolete regulation of replicative cell aging OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging. go-plus.json regulation of replicative cell ageing http://purl.obolibrary.org/obo/GO_1900062 CHEBI:132540 biolink:ChemicalSubstance fatty acid 20:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132540 GO:1900061 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling. go-plus.json up regulation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|activation of transcription from RNA polymerase II promoter of calcium signalling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium signalling|positive regulation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from RNA polymerase II promoter of calcium signalling|upregulation of global transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from Pol II promoter of calcium ion signaling|positive regulation of transcription from Pol II promoter of calcium-mediated signalling|activation of transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter of calcium signalling|activation of global transcription from RNA polymerase II promoter of calcium signalling|upregulation of transcription from RNA polymerase II promoter of calcium signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up-regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium signalling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signalling|activation of transcription from RNA polymerase II promoter of calcium-mediated signalling|activation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|stimulation of transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of global transcription from RNA polymerase II promoter of calcium signaling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from Pol II promoter of calcium signalling|positive regulation of transcription from Pol II promoter of calcium signaling|up regulation of global transcription from RNA polymerase II promoter of calcium signalling|stimulation of global transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signaling|activation of transcription from RNA polymerase II promoter of calcium signaling|upregulation of transcription from RNA polymerase II promoter of calcium signalling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signalling|stimulation of transcription from RNA polymerase II promoter of calcium signaling|activation of global transcription from RNA polymerase II promoter of calcium ion signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of transcription from RNA polymerase II promoter of calcium ion signaling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter of calcium signaling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter of calcium signaling|upregulation of global transcription from RNA polymerase II promoter of calcium signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|positive regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from Pol II promoter of calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter of calcium signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of global transcription from Pol II promoter of calcium signaling|up regulation of transcription from RNA polymerase II promoter of calcium signalling|activation of global transcription from RNA polymerase II promoter of calcium signaling http://purl.obolibrary.org/obo/GO_1900061 GO:1900064 biolink:BiologicalProcess positive regulation of peroxisome organization Any process that activates or increases the frequency, rate or extent of peroxisome organization. go-plus.json up regulation of peroxisome-assembly ATPase activity|positive regulation of peroxisome-assembly ATPase activity|upregulation of peroxisome organization and biogenesis|upregulation of peroxisome organisation|up-regulation of peroxisome organization|activation of peroxisome-assembly ATPase activity|up-regulation of peroxisome organization and biogenesis|up-regulation of peroxisome-assembly ATPase activity|up regulation of peroxisome organisation|activation of peroxisome organisation|upregulation of peroxisome organization|positive regulation of peroxisome organisation|activation of peroxisome organization and biogenesis|upregulation of peroxisome-assembly ATPase activity|activation of peroxisome organization|positive regulation of peroxisome organization and biogenesis|up regulation of peroxisome organization and biogenesis|up regulation of peroxisome organization|up-regulation of peroxisome organisation http://purl.obolibrary.org/obo/GO_1900064 GO:1900063 biolink:BiologicalProcess regulation of peroxisome organization Any process that modulates the frequency, rate or extent of peroxisome organization. go-plus.json regulation of peroxisome organization and biogenesis|regulation of peroxisome organisation|regulation of peroxisome-assembly ATPase activity http://purl.obolibrary.org/obo/GO_1900063 CHEBI:132541 biolink:ChemicalSubstance fatty acid 22:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132541 CHEBI:132544 biolink:ChemicalSubstance fatty acid 22:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132544 CHEBI:50390 biolink:ChemicalSubstance EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50390 CHEBI:132543 biolink:ChemicalSubstance fatty acid 22:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132543 GO:1900060 biolink:BiologicalProcess negative regulation of ceramide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process. go-plus.json down-regulation of ceramide biosynthetic process|downregulation of ceramide anabolism|down regulation of ceramide anabolism|downregulation of ceramide synthesis|inhibition of ceramide biosynthesis|downregulation of ceramide formation|down regulation of ceramide synthesis|down regulation of ceramide formation|inhibition of ceramide anabolism|inhibition of ceramide biosynthetic process|down regulation of ceramide biosynthesis|inhibition of ceramide synthesis|inhibition of ceramide formation|downregulation of ceramide biosynthesis|down regulation of ceramide biosynthetic process|negative regulation of ceramide anabolism|downregulation of ceramide biosynthetic process|down-regulation of ceramide anabolism|negative regulation of ceramide synthesis|down-regulation of ceramide synthesis|down-regulation of ceramide biosynthesis|negative regulation of ceramide biosynthesis|negative regulation of ceramide formation|down-regulation of ceramide formation http://purl.obolibrary.org/obo/GO_1900060 CHEBI:50398 biolink:ChemicalSubstance succinamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50398 GO:0072279 biolink:BiologicalProcess convergent extension involved in metanephric nephron morphogenesis The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072279 GO:0072278 biolink:BiologicalProcess metanephric comma-shaped body morphogenesis The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072278 GO:0072277 biolink:BiologicalProcess metanephric glomerular capillary formation The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0072277 GO:0072265 biolink:BiologicalProcess metanephric capsule morphogenesis The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go-plus.json http://purl.obolibrary.org/obo/GO_0072265 GO:0072264 biolink:BiologicalProcess metanephric glomerular endothelium development The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072264 GO:0072263 biolink:BiologicalProcess metanephric intraglomerular mesangial cell proliferation The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0072263 CHEBI:50389 biolink:ChemicalSubstance alpha-D-Glcp-(1->6)-alpha-D-Glcp-(1->6)-alpha-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_50389 chebi_ph7_3 GO:0072262 biolink:BiologicalProcess metanephric glomerular mesangial cell proliferation involved in metanephros development The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population. go-plus.json http://purl.obolibrary.org/obo/GO_0072262 CHEBI:50388 biolink:ChemicalSubstance tuberculosinyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50388 GO:0072261 biolink:BiologicalProcess metanephric extraglomerular mesangial cell proliferation involved in metanephros development The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. go-plus.json metanephric Goormaghtigh proliferation|metanephric lacis cell proliferation http://purl.obolibrary.org/obo/GO_0072261 GO:0072260 biolink:BiologicalProcess metanephric interstitial fibroblast fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast. go-plus.json metanephros interstitial cell fate commitment http://purl.obolibrary.org/obo/GO_0072260 CHEBI:132559 biolink:ChemicalSubstance lysophosphatidylethanolamine 20:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132559 GO:1900069 biolink:BiologicalProcess regulation of cellular hyperosmotic salinity response Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response. go-plus.json regulation of cellular response to hyperosmotic salt stress http://purl.obolibrary.org/obo/GO_1900069 NCBITaxon:23513 biolink:OrganismalEntity Rutaceae go-plus.json rue family http://purl.obolibrary.org/obo/NCBITaxon_23513 GO:1900066 biolink:BiologicalProcess positive regulation of ethanol catabolic process Any process that activates or increases the frequency, rate or extent of ethanol catabolic process. go-plus.json upregulation of ethanol degradation|upregulation of ethanol catabolism|up-regulation of ethanol catabolic process|upregulation of ethanol breakdown|activation of ethanol catabolism|up regulation of ethanol degradation|up-regulation of ethanol catabolism|activation of ethanol degradation|positive regulation of ethanol degradation|upregulation of ethanol catabolic process|up regulation of ethanol breakdown|activation of ethanol breakdown|positive regulation of ethanol breakdown|activation of ethanol catabolic process|positive regulation of ethanol catabolism|up-regulation of ethanol degradation|up regulation of ethanol catabolic process|up regulation of ethanol catabolism|up-regulation of ethanol breakdown http://purl.obolibrary.org/obo/GO_1900066 GO:1900065 biolink:BiologicalProcess regulation of ethanol catabolic process Any process that modulates the frequency, rate or extent of ethanol catabolic process. go-plus.json regulation of ethanol degradation|regulation of ethanol breakdown|regulation of ethanol catabolism http://purl.obolibrary.org/obo/GO_1900065 GO:1900068 biolink:BiologicalProcess negative regulation of cellular response to alkaline pH Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity. go-plus.json downregulation of cellular response to alkaline pH|down regulation of cellular response to alkaline pH|down-regulation of cellular response to alkalinity|inhibition of cellular response to alkaline pH|down regulation of cellular response to basic pH|inhibition of cellular response to alkalinity|downregulation of cellular response to basic pH|negative regulation of cellular response to basic pH|down-regulation of cellular response to basic pH|down-regulation of cellular response to alkaline pH|down regulation of cellular response to alkalinity|inhibition of cellular response to basic pH|downregulation of cellular response to alkalinity|negative regulation of cellular response to alkalinity http://purl.obolibrary.org/obo/GO_1900068 GO:1900067 biolink:BiologicalProcess regulation of cellular response to alkaline pH Any process that modulates the frequency, rate or extent of cellular response to alkalinity. go-plus.json regulation of cellular response to basic pH|regulation of cellular response to alkalinity http://purl.obolibrary.org/obo/GO_1900067 GO:1900073 biolink:BiologicalProcess regulation of neuromuscular synaptic transmission Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_1900073 GO:1900072 biolink:BiologicalProcess positive regulation of sulfite transport Any process that activates or increases the frequency, rate or extent of sulfite transport. go-plus.json up regulation of sulfite transport|up-regulation of sulphite transport|activation of sulphite transport|up-regulation of sulfite transport|positive regulation of sulphite transport|up regulation of sulphite transport|upregulation of sulfite transport|upregulation of sulphite transport|activation of sulfite transport http://purl.obolibrary.org/obo/GO_1900072 GO:1900075 biolink:BiologicalProcess positive regulation of neuromuscular synaptic transmission Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission. go-plus.json up regulation of neuromuscular synaptic transmission|activation of neuromuscular synaptic transmission|up-regulation of neuromuscular synaptic transmission|upregulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_1900075 GO:1900074 biolink:BiologicalProcess negative regulation of neuromuscular synaptic transmission Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission. go-plus.json down-regulation of neuromuscular synaptic transmission|inhibition of neuromuscular synaptic transmission|down regulation of neuromuscular synaptic transmission|downregulation of neuromuscular synaptic transmission http://purl.obolibrary.org/obo/GO_1900074 CHEBI:132554 biolink:ChemicalSubstance oligomer go-plus.json http://purl.obolibrary.org/obo/CHEBI_132554 GO:1900071 biolink:BiologicalProcess regulation of sulfite transport Any process that modulates the frequency, rate or extent of sulfite transport. go-plus.json regulation of sulphite transport http://purl.obolibrary.org/obo/GO_1900071 GO:1900070 biolink:BiologicalProcess negative regulation of cellular hyperosmotic salinity response Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response. go-plus.json down regulation of cellular response to hyperosmotic salt stress|down-regulation of cellular hyperosmotic salinity response|inhibition of cellular hyperosmotic salinity response|downregulation of cellular response to hyperosmotic salt stress|negative regulation of cellular response to hyperosmotic salt stress|down-regulation of cellular response to hyperosmotic salt stress|inhibition of cellular response to hyperosmotic salt stress|down regulation of cellular hyperosmotic salinity response|downregulation of cellular hyperosmotic salinity response http://purl.obolibrary.org/obo/GO_1900070 CHEBI:50383 biolink:ChemicalSubstance nicotinamide mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50383 CHEBI:50387 biolink:ChemicalSubstance tuberculosinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50387 chebi_ph7_3 GO:0072269 biolink:BiologicalProcess metanephric long descending thin limb development The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. go-plus.json http://purl.obolibrary.org/obo/GO_0072269 GO:0072268 biolink:BiologicalProcess pattern specification involved in metanephros development Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate. go-plus.json pattern formation involved in metanephros development|metanephros pattern specification|metanephros pattern formation http://purl.obolibrary.org/obo/GO_0072268 GO:0072267 biolink:BiologicalProcess metanephric capsule specification The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0072267 GO:0072266 biolink:BiologicalProcess metanephric capsule formation The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. go-plus.json http://purl.obolibrary.org/obo/GO_0072266 CHEBI:74347 biolink:ChemicalSubstance FMN-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74347 GO:0106276 biolink:MolecularActivity biliberdin reductase NAD+ activity Catalysis of the reaction: bilirubin + NAD+ = biliverdin + NADH+ H+. EC:1.3.1.24|RHEA:15797 go-plus.json http://purl.obolibrary.org/obo/GO_0106276 GO:0106275 biolink:MolecularActivity NADP+-protein-arginine ADP-ribosyltransferase activity Catalysis of the reaction: NADP+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. RHEA:54884|EC:2.4.2.31 go-plus.json http://purl.obolibrary.org/obo/GO_0106275 CHEBI:74346 biolink:ChemicalSubstance FMN-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74346 GO:0106274 biolink:MolecularActivity NAD+-protein-arginine ADP-ribosyltransferase activity Catalysis of the reaction: NAD+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. EC:2.4.2.31|RHEA:19149 go-plus.json http://purl.obolibrary.org/obo/GO_0106274 GO:0106273 biolink:BiologicalProcess cytosol to ERGIC protein transport The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC). go-plus.json http://purl.obolibrary.org/obo/GO_0106273 UBERON:0012283 biolink:AnatomicalEntity femoral fat pad encapsulated adipose tissue associated with the femur go-plus.json femoral fat depot http://purl.obolibrary.org/obo/UBERON_0012283 GO:0106279 biolink:BiologicalProcess negative regulation of UDP-N-acetylglucosamine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process. go-plus.json negative regulation of UDP-N-acetylglucosamine synthesis|negative regulation of UDP-N-acetylglucosamine formation|negative regulation of UDP-N-acetylglucosamine biosynthesis|negative regulation of UDP-GlcNAc biosynthesis|negative regulation of UDP-GlcNAc biosynthetic process|negative regulation of UDP-N-acetylglucosamine anabolism http://purl.obolibrary.org/obo/GO_0106279 GO:0106278 biolink:BiologicalProcess regulation of UDP-N-acetylglucosamine biosynthetic process Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process. go-plus.json regulation of UDP-GlcNAc biosynthetic process|regulation of UDP-N-acetylglucosamine anabolism|regulation of UDP-N-acetylglucosamine biosynthesis|regulation of UDP-N-acetylglucosamine synthesis|regulation of UDP-N-acetylglucosamine formation http://purl.obolibrary.org/obo/GO_0106278 UBERON:0012282 biolink:AnatomicalEntity mammary fat pad encapsulated adipose tissue associated with the mammary gland go-plus.json http://purl.obolibrary.org/obo/UBERON_0012282 UBERON:0036253 biolink:AnatomicalEntity orifice of skull go-plus.json skull orifice|cranial orifice http://purl.obolibrary.org/obo/UBERON_0036253 GO:0106277 biolink:MolecularActivity biliverdin reductase (NADP+) activity Catalysis of the reaction: bilirubin + NADP+ = biliverdin + NADPH + H+. EC:1.3.1.24|RHEA:15793 go-plus.json http://purl.obolibrary.org/obo/GO_0106277 UBERON:0036255 biolink:AnatomicalEntity interoceptive system The system that is responsible for sensing the internal state of the body. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036255 UBERON:0012287 biolink:AnatomicalEntity Rathkes pouch epithelium A epithelial sac that is part of a Rathke's pouch. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012287 CHEBI:74340 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74340 chebi_ph7_3 GO:0106283 biolink:MolecularActivity ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity Catalysis of the reaction: NAD(+) + ursodeoxycholate = 7-oxolithocholate + H(+) + NADH. RHEA:42028 go-plus.json http://purl.obolibrary.org/obo/GO_0106283 GO:0106282 biolink:MolecularActivity isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH. RHEA:42024 go-plus.json http://purl.obolibrary.org/obo/GO_0106282 CHEBI:74345 biolink:ChemicalSubstance 1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea go-plus.json http://purl.obolibrary.org/obo/CHEBI_74345 chebi_ph7_3 GO:0106281 biolink:MolecularActivity chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity Catalysis of the reaction: chenodeoxycholate + NAD(+) = 7-oxolithocholate + H(+) + NADH. RHEA:42036 go-plus.json http://purl.obolibrary.org/obo/GO_0106281 GO:0106280 biolink:BiologicalProcess positive regulation of UDP-N-acetylglucosamine biosynthetic process Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process. go-plus.json positive regulation of UDP-N-acetylglucosamine anabolism|positive regulation of UDP-N-acetylglucosamine synthesis|positive egulation of UDP-N-acetylglucosamine formation|positive regulation of UDP-N-acetylglucosamine biosynthesis|positive regulation of UDP-GlcNAc biosynthetic process http://purl.obolibrary.org/obo/GO_0106280 CHEBI:74344 biolink:ChemicalSubstance 1-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74344 chebi_ph7_3 CHEBI:74358 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74358 GO:0106287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0106287 GO:0106286 biolink:MolecularActivity (E)-caffeate-CoA ligase activity Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate. RHEA:36299 go-plus.json http://purl.obolibrary.org/obo/GO_0106286 CHEBI:74359 biolink:ChemicalSubstance L-alpha-aminobutyrate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74359 chebi_ph7_3 UBERON:0036262 biolink:AnatomicalEntity uterine ligament Any of the eight ligaments pertaining to the uterus including the anterior, posterior, lateral, sacro-uterine and round ligaments. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036262 UBERON:0036264 biolink:AnatomicalEntity zygomaticotemporal nerve The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit. go-plus.json zygomaticotemporal branch|zygomaticotemporal|zygomaticotemporal branch of zygomatic nerve|ramus zygomaticotemporalis (Nervus zygomaticus)|ramus zygomaticotemporalis nervus zygomatici http://purl.obolibrary.org/obo/UBERON_0036264 GO:0106289 biolink:BiologicalProcess negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0106289 GO:0106288 biolink:BiologicalProcess regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0106288 UBERON:0012276 biolink:AnatomicalEntity endometrium glandular epithelium go-plus.json glandular part of endometrium|uterine glands set|uterine glands http://purl.obolibrary.org/obo/UBERON_0012276 UBERON:0036268 biolink:AnatomicalEntity pelvic vein go-plus.json http://purl.obolibrary.org/obo/UBERON_0036268 UBERON:0012275 biolink:AnatomicalEntity meso-epithelium Epithelium that derives from the mesoderm. [Automatically generated definition]. go-plus.json mesoderm-derived epithelium|mesoepithelium http://purl.obolibrary.org/obo/UBERON_0012275 UBERON:0012274 biolink:AnatomicalEntity columnar epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified] go-plus.json http://purl.obolibrary.org/obo/UBERON_0012274 UBERON:0036267 biolink:AnatomicalEntity vulval vein go-plus.json http://purl.obolibrary.org/obo/UBERON_0036267 UBERON:0036269 biolink:AnatomicalEntity penis blood vessel go-plus.json penis vasculature|vasculature of penis http://purl.obolibrary.org/obo/UBERON_0036269 UBERON:0012278 biolink:AnatomicalEntity gland of nasal mucosa The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands. go-plus.json nasal gland|glandula nasalis|glandulae nasales http://purl.obolibrary.org/obo/UBERON_0012278 GO:0106290 biolink:MolecularActivity trans-cinnamate-CoA ligase activity Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate. RHEA:64788 go-plus.json http://purl.obolibrary.org/obo/GO_0106290 CHEBI:74351 biolink:ChemicalSubstance aclacinomycin T go-plus.json http://purl.obolibrary.org/obo/CHEBI_74351 GO:0106294 biolink:MolecularActivity NADPH oxidase H202-forming activity Catalysis of the reaction: NADPH + H+ + O2 = NADP + hydrogen peroxide (H2O2). RHEA:11260 go-plus.json http://purl.obolibrary.org/obo/GO_0106294 CHEBI:74354 biolink:ChemicalSubstance 15-demethylaclacinomycin T zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74354 chebi_ph7_3 GO:0106293 biolink:MolecularActivity NADH oxidase H202-forming activity Catalysis of the reaction: NADH + H+ + O2 = NAD + hydrogen peroxide (H2O2). RHEA:11264 go-plus.json http://purl.obolibrary.org/obo/GO_0106293 CHEBI:74353 biolink:ChemicalSubstance aclacinomycin A(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74353 GO:0106292 biolink:MolecularActivity superoxide-generating NADPH oxidase activity Catalysis of the reaction: NADPH + 2 O2 = H(+) + NADP(+) + 2 superoxide. RHEA:63180 go-plus.json http://purl.obolibrary.org/obo/GO_0106292 GO:0106291 biolink:MolecularActivity superoxide-generating NADH oxidase activity. Catalysis of the reaction: NADH + 2 O2 = H(+) + NAD(+) + 2 superoxide. RHEA:63184 go-plus.json http://purl.obolibrary.org/obo/GO_0106291 CHEBI:74355 biolink:ChemicalSubstance 3-oxotriacontanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74355 GO:0106298 biolink:BiologicalProcess 13-series resolvin biosynthetic process The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0106298 GO:0106297 biolink:BiologicalProcess E-series resolvin biosynthetic process The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0106297 GO:0106296 biolink:BiologicalProcess D-series resolvin biosynthetic process The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0106296 GO:0106295 biolink:BiologicalProcess resolvin biosynthetic process The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0106295 GO:0106299 biolink:BiologicalProcess resolution phase response An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function. go-plus.json http://purl.obolibrary.org/obo/GO_0106299 CHEBI:74361 biolink:ChemicalSubstance 5-oxo-delta-bilirubin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74361 chebi_ph7_3 CHEBI:74360 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z,25Z)-3-oxooctacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74360 CHEBI:74363 biolink:ChemicalSubstance Ala-Asp(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74363 chebi_ph7_3 CHEBI:74362 biolink:ChemicalSubstance 15-oxo-beta-bilirubin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74362 chebi_ph7_3 CHEBI:74364 biolink:ChemicalSubstance phosphatidylinositol 28:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74364 chebi_ph7_3 UBERON:0012251 biolink:AnatomicalEntity ectocervical epithelium A epithelium that is part of a ectocervix. go-plus.json exocervical epithelium http://purl.obolibrary.org/obo/UBERON_0012251 UBERON:0012250 biolink:AnatomicalEntity cervix glandular epithelium A glandular epithelium that is part of a uterine cervix. go-plus.json cervix columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012250 UBERON:0036286 biolink:AnatomicalEntity wall of right ventricle Wall of ventricle which is continuous with the wall of pulmonary trunk. go-plus.json right ventricular wall http://purl.obolibrary.org/obo/UBERON_0036286 UBERON:0036285 biolink:AnatomicalEntity wall of left ventricle Wall of ventricle which is continuous with the wall of aorta. go-plus.json left ventricular wall http://purl.obolibrary.org/obo/UBERON_0036285 GO:0047207 biolink:MolecularActivity 1,2-beta-fructan 1F-fructosyltransferase activity Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1). MetaCyc:2.4.1.100-RXN|EC:2.4.1.100 go-plus.json 2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|1,2-beta-D-fructan 1(F)-fructosyltransferase activity|1,2-beta-D-fructan 1F-fructosyltransferase activity|1,2-beta-fructan 1(F)-fructosyltransferase activity|2,1-fructan:2,1-fructan 1-fructosyltransferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity|fructan:fructan fructosyl transferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity|FFT activity http://purl.obolibrary.org/obo/GO_0047207 UBERON:0036288 biolink:AnatomicalEntity anterior wall of left ventricle go-plus.json http://purl.obolibrary.org/obo/UBERON_0036288 GO:0047206 biolink:MolecularActivity UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA. MetaCyc:2.3.2.10-RXN|EC:2.3.2.10|RHEA:12432 go-plus.json L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity|L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity|UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity|alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity|UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity http://purl.obolibrary.org/obo/GO_0047206 UBERON:0012254 biolink:AnatomicalEntity abdominal aorta artery An artery that originates from the abdominal aorta go-plus.json abdominal artery|artery of abdomen http://purl.obolibrary.org/obo/UBERON_0012254 GO:0047205 biolink:MolecularActivity quinate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA. MetaCyc:2.3.1.99-RXN|EC:2.3.1.99|RHEA:15021 go-plus.json hydroxycinnamoyl coenzyme A-quinate transferase activity|feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity http://purl.obolibrary.org/obo/GO_0047205 UBERON:0012253 biolink:AnatomicalEntity cervical squamo-columnar junction Region of cervical epithelium where columnar epithelium of endocervic and the stratified non-keratinising squamous epithelium of the ectocervic meet go-plus.json squamocolumnar junction|squamo-columnar junction of uterine cervix|squamocolumnar junction of uterine cervix http://purl.obolibrary.org/obo/UBERON_0012253 GO:0047204 biolink:MolecularActivity chlorogenate-glucarate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate. MetaCyc:2.3.1.98-RXN|KEGG_REACTION:R02998|EC:2.3.1.98|RHEA:23204 go-plus.json chlorogenic acid:glucaric acid O-caffeoyltransferase activity|chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity|chlorogenate:glucarate caffeoyltransferase activity http://purl.obolibrary.org/obo/GO_0047204 UBERON:0012252 biolink:AnatomicalEntity endocervical epithelium The glandular epithelium that lines the endocervix. go-plus.json endocervical glandular epithelium http://purl.obolibrary.org/obo/UBERON_0012252 UBERON:0036289 biolink:AnatomicalEntity anterior wall of right ventricle Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036289 GO:0047203 biolink:MolecularActivity 13-hydroxylupinine O-tigloyltransferase activity Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA. MetaCyc:2.3.1.93-RXN|KEGG_REACTION:R04205|EC:2.3.1.93|RHEA:12360 go-plus.json (E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity|tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity|13-hydroxylupanine acyltransferase activity http://purl.obolibrary.org/obo/GO_0047203 GO:0047202 biolink:MolecularActivity sinapoylglucose-choline O-sinapoyltransferase activity Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose. MetaCyc:2.3.1.91-RXN|RHEA:12024|EC:2.3.1.91|KEGG_REACTION:R03075 go-plus.json 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity|sinapine synthase activity http://purl.obolibrary.org/obo/GO_0047202 GO:0047201 biolink:MolecularActivity beta-glucogallin O-galloyltransferase activity Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose. MetaCyc:2.3.1.90-RXN|RHEA:11416|KEGG_REACTION:R00049|EC:2.3.1.90 go-plus.json 1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity http://purl.obolibrary.org/obo/GO_0047201 GO:0047200 biolink:MolecularActivity tetrahydrodipicolinate N-acetyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA. EC:2.3.1.89|KEGG_REACTION:R04364|RHEA:13085|MetaCyc:2.3.1.89-RXN go-plus.json acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity|tetrahydrodipicolinate acetylase activity|acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity|tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity|acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0047200 UBERON:0012249 biolink:AnatomicalEntity ectocervix The part of the cervix uteri that protrudes into the vagina and is lined with stratified squamous epithelium. go-plus.json ectocervix|portio vaginalis cervicis|exocervix|vaginal part of cervix|portio vaginalis|uterine ectocervix http://purl.obolibrary.org/obo/UBERON_0012249 GO:0047209 biolink:MolecularActivity coniferyl-alcohol glucosyltransferase activity Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP. EC:2.4.1.111|RHEA:23944|MetaCyc:2.4.1.111-RXN go-plus.json UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|UDP-glucose coniferyl alcohol glucosyltransferase activity|uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047209 GO:0047208 biolink:MolecularActivity o-dihydroxycoumarin 7-O-glucosyltransferase activity Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP. KEGG_REACTION:R03548|RHEA:14325|MetaCyc:2.4.1.104-RXN|EC:2.4.1.104 go-plus.json uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity|UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047208 CL:1000182 biolink:Cell malpighian tubule tip cell go-plus.json http://purl.obolibrary.org/obo/CL_1000182 GO:0106232 biolink:CellularComponent hydroxyisourate hydrolase complex A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin. go-plus.json HIU hydrolase complex|5-hydroxyisourate hydrolase complex|HIUH complex http://purl.obolibrary.org/obo/GO_0106232 GO:0047210 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047210 GO:0106231 biolink:MolecularActivity protein-propionyllysine depropionylase activity Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. RHEA:23500 go-plus.json http://purl.obolibrary.org/obo/GO_0106231 GO:0106230 biolink:BiologicalProcess protein depropionylation The removal of a propionyl group from a residue in a peptide or protein. go-plus.json http://purl.obolibrary.org/obo/GO_0106230 GO:0106236 biolink:BiologicalProcess rhamnolipid biosynthesis The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal. go-plus.json rhamnolipid production http://purl.obolibrary.org/obo/GO_0106236 GO:0106235 biolink:MolecularActivity ceramide-1-phosphate phosphatase activity Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate. RHEA:50888 go-plus.json http://purl.obolibrary.org/obo/GO_0106235 GO:0106234 biolink:CellularComponent outer membrane protein complex Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC. go-plus.json http://purl.obolibrary.org/obo/GO_0106234 GO:0106233 biolink:BiologicalProcess glycosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis. go-plus.json glycosome organization and biogenesis|glycosome biogenesis|glycosome organisation http://purl.obolibrary.org/obo/GO_0106233 GO:0047218 biolink:MolecularActivity hydroxycinnamate 4-beta-glucosyltransferase activity Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP. MetaCyc:2.4.1.126-RXN|EC:2.4.1.126|RHEA:21636 go-plus.json uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity|UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|UDP-glucose-hydroxycinnamate glucosyltransferase activity|hydroxycinnamoyl glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047218 GO:0106239 biolink:MolecularActivity 9,13-epoxylabda-14-ene synthase activity Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate. EC:4.2.3.189|RHEA:54512 go-plus.json http://purl.obolibrary.org/obo/GO_0106239 GO:0047217 biolink:MolecularActivity sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose. MetaCyc:2.4.1.125-RXN|EC:2.4.1.125 go-plus.json water-soluble-glucan synthase activity|sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity|GTF-S|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase|sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047217 GO:0106238 biolink:MolecularActivity peregrinol diphosphate synthase activity Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O. EC:4.2.1.174|RHEA:54652 go-plus.json http://purl.obolibrary.org/obo/GO_0106238 GO:0047216 biolink:MolecularActivity inositol 3-alpha-galactosyltransferase activity Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP. RHEA:12464|MetaCyc:2.4.1.123-RXN|EC:2.4.1.123 go-plus.json uridine diphosphogalactose-inositol galactosyltransferase activity|UDP-D-galactose:inositol galactosyltransferase activity|UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity|galactinol synthase activity|UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity|UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity|inositol 1-alpha-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047216 GO:0047215 biolink:MolecularActivity indole-3-acetate beta-glucosyltransferase activity Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP. RHEA:14921|MetaCyc:2.4.1.121-RXN|KEGG_REACTION:R03094|EC:2.4.1.121 go-plus.json indol-3-ylacetylglucose synthase activity|IAA-glucose synthase activity|UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity|uridine diphosphoglucose-indoleacetate glucosyltransferase activity|UDP-glucose:indol-3-acetic acid glucosyltransferase activity|UDP-glucose:indol-3-ylacetate glucosyl-transferase activity|IAA-Glu synthetase activity|IAGlu synthase activity|UDP-glucose:auxin glucosyltransferase activity|UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity|UDPG-indol-3-ylacetyl glucosyl transferase activity|UDP-glucose:indol-3-ylacetate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047215 GO:0106237 biolink:MolecularActivity arachidonate 12(R)-lipoxygenase activity Catalysis of the reaction: arachidonate + O(2)=(5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate. RHEA:41336 go-plus.json http://purl.obolibrary.org/obo/GO_0106237 GO:0047214 biolink:MolecularActivity cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP. MetaCyc:2.4.1.116-RXN|RHEA:12144|EC:2.4.1.116 go-plus.json uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity|cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047214 UBERON:0036215 biolink:AnatomicalEntity anatomical surface region Material anatomical entity that forms the outermost boundary of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036215 GO:0047213 biolink:MolecularActivity anthocyanidin 3-O-glucosyltransferase activity Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP. MetaCyc:2.4.1.115-RXN|EC:2.4.1.115|RHEA:20093 go-plus.json 3-GT activity|UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-glucosyltransferase activity|UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity|uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity|UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047213 UBERON:0036214 biolink:AnatomicalEntity rectosigmoid junction An anatomical junction that is between the sigmoid colon and rectum. go-plus.json rectosigmoid region http://purl.obolibrary.org/obo/UBERON_0036214 GO:0047212 biolink:MolecularActivity 2-coumarate O-beta-glucosyltransferase activity Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP. KEGG_REACTION:R03710|MetaCyc:2.4.1.114-RXN|EC:2.4.1.114|RHEA:10236 go-plus.json UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPG:o-coumaric acid O-glucosyltransferase activity|uridine diphosphoglucose-o-coumarate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047212 UBERON:0036217 biolink:AnatomicalEntity coelomic fluid A bodily fluid that is located in the coelom. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036217 GO:0047211 biolink:MolecularActivity alpha-1,4-glucan-protein synthase (ADP-forming) activity Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP. MetaCyc:2.4.1.113-RXN|EC:2.4.1.113 go-plus.json 1,4alpha-glucan-protein synthase (ADP-forming) activity|ADPglucose:protein 4-alpha-D-glucosyltransferase activity|adenosine diphosphoglucose-protein glucosyltransferase activity|ADP-glucose:protein 4-alpha-D-glucosyltransferase activity|ADPglucose:protein glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047211 CL:0002584 biolink:Cell renal cortical epithelial cell An epithelial cell of the kidney cortex. go-plus.json http://purl.obolibrary.org/obo/CL_0002584 CL:0002586 biolink:Cell retinal pigment epithelial cell An epithelial cell of the retinal pigmented epithelium. go-plus.json http://purl.obolibrary.org/obo/CL_0002586 CL:0002585 biolink:Cell retinal blood vessel endothelial cell A blood vessel endothelial cell that is part of the retina. go-plus.json http://purl.obolibrary.org/obo/CL_0002585 GO:0047219 biolink:MolecularActivity monoterpenol beta-glucosyltransferase activity Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP. MetaCyc:2.4.1.127-RXN|RHEA:11520|KEGG_REACTION:R02179|EC:2.4.1.127 go-plus.json UDPglucose:monoterpenol glucosyltransferase activity|UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity|UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-monoterpenol glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047219 NCBITaxon:47570 biolink:OrganismalEntity Schizotrypanum go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_47570 CHEBI:74387 biolink:ChemicalSubstance Ala-Gln zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74387 chebi_ph7_3 CHEBI:74389 biolink:ChemicalSubstance Ala-Leu zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74389 chebi_ph7_3 CHEBI:74388 biolink:ChemicalSubstance Ala-His zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74388 chebi_ph7_3 GO:0106243 biolink:MolecularActivity syn-isopimara-7,15-diene synthase activity Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene. RHEA:62188 go-plus.json http://purl.obolibrary.org/obo/GO_0106243 GO:0047221 biolink:MolecularActivity sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP. KEGG_REACTION:R00853|MetaCyc:2.4.1.137-RXN|EC:2.4.1.137|RHEA:14285 go-plus.json UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|floridoside-phosphate synthase activity|FPS|UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|floridoside phosphate synthetase activity|UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity|floridoside phosphate synthase activity http://purl.obolibrary.org/obo/GO_0047221 GO:0047220 biolink:MolecularActivity galactosylxylosylprotein 3-beta-galactosyltransferase activity Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP. Reactome:R-HSA-4420365|Reactome:R-HSA-1889978|MetaCyc:2.4.1.134-RXN|RHEA:11780|EC:2.4.1.134 go-plus.json UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity|uridine diphosphogalactose-galactosylxylose galactosyltransferase activity|UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity|galactosyltransferase II activity http://purl.obolibrary.org/obo/GO_0047220 GO:0106242 biolink:MolecularActivity kolavenyl diphosphate synthase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate. RHEA:54676|EC:5.5.1.29 go-plus.json http://purl.obolibrary.org/obo/GO_0106242 GO:0106240 biolink:MolecularActivity labd-13Z-ene-9,15,16-triol synthase activity Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]. RHEA:62192 go-plus.json http://purl.obolibrary.org/obo/GO_0106240 GO:0106247 biolink:BiologicalProcess negative regulation of poly(A)-specific ribonuclease activity Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_0106247 GO:0106246 biolink:BiologicalProcess regulation of poly(A)-specific ribonuclease activity Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. go-plus.json http://purl.obolibrary.org/obo/GO_0106246 GO:0106245 biolink:MolecularActivity L-serine-phosphatidylethanolamine phosphatidyltransferase activity Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine. RHEA:27606|EC:2.7.8.29 go-plus.json http://purl.obolibrary.org/obo/GO_0106245 GO:0106244 biolink:MolecularActivity eupatolide synthase activity Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:57972|EC:1.14.14.169 go-plus.json http://purl.obolibrary.org/obo/GO_0106244 GO:0047229 biolink:MolecularActivity 13-hydroxydocosanoate 13-beta-glucosyltransferase activity Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP. RHEA:22316|EC:2.4.1.158|MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN go-plus.json UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity|UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity|13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047229 GO:0047228 biolink:MolecularActivity 1,2-diacylglycerol 3-glucosyltransferase activity Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP. MetaCyc:2.4.1.157-RXN|EC:2.4.1.157 go-plus.json UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity|UDP-glucose-diacylglycerol glucosyltransferase activity|UDPglucose:diacylglycerol glucosyltransferase activity|UDP-glucose:1,2-diacylglycerol glucosyltransferase activity|uridine diphosphoglucose-diacylglycerol glucosyltransferase activity|UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047228 GO:0106249 biolink:CellularComponent Nicalin-NOMO complex A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147. go-plus.json Nicalin-TMEM147-NOMO complex http://purl.obolibrary.org/obo/GO_0106249 UBERON:0036224 biolink:AnatomicalEntity corticobulbar and corticospinal tracts The corticobulbar and corticospinal tracts combined. go-plus.json pyramidal tract http://purl.obolibrary.org/obo/UBERON_0036224 GO:0047227 biolink:MolecularActivity indolylacetyl-myo-inositol galactosyltransferase activity Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP. RHEA:21148|KEGG_REACTION:R04334|MetaCyc:2.4.1.156-RXN|EC:2.4.1.156 go-plus.json uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity|indol-3-ylacetyl-myo-inositol galactoside synthase activity|UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity|UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047227 GO:0106248 biolink:BiologicalProcess positive regulation of poly(A)-specific ribonuclease activity Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity. go-plus.json http://purl.obolibrary.org/obo/GO_0106248 GO:0047226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047226 GO:0047225 biolink:MolecularActivity acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP. MetaCyc:2.4.1.148-RXN|EC:2.4.1.148|RHEA:16552 go-plus.json O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|core 6-beta-GalNAc-transferase B activity|UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B|core 6beta-GalNAc-transferase B|core 4 beta6-GalNAc-transferase activity http://purl.obolibrary.org/obo/GO_0047225 GO:0047224 biolink:MolecularActivity acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP. MetaCyc:2.4.1.147-RXN|EC:2.4.1.147|RHEA:14252 go-plus.json O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|mucin core 3 beta3-GlcNAc-transferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity|core 3-beta-GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|core 3beta-GlcNAc-transferase activity http://purl.obolibrary.org/obo/GO_0047224 UBERON:0036225 biolink:AnatomicalEntity respiratory system gland Any gland that is part os the respiratory system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036225 GO:0047223 biolink:MolecularActivity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP. Reactome:R-HSA-5617096|MetaCyc:2.4.1.146-RXN|EC:2.4.1.146|Reactome:R-HSA-5617037 go-plus.json UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)|elongation 3beta-GalNAc-transferase activity|elongation 3-beta-GalNAc-transferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity http://purl.obolibrary.org/obo/GO_0047223 GO:0047222 biolink:MolecularActivity mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP. RHEA:13705|MetaCyc:2.4.1.138-RXN|EC:2.4.1.138 go-plus.json alpha-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047222 CL:0002597 biolink:Cell smooth muscle cell of bladder A smooth muscle cell of the bladder. go-plus.json http://purl.obolibrary.org/obo/CL_0002597 CL:1000123 biolink:Cell metanephric nephron tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000123 CL:0002599 biolink:Cell smooth muscle cell of the esophagus A smooth muscle cell of the esophagus. go-plus.json http://purl.obolibrary.org/obo/CL_0002599 CHEBI:74390 biolink:ChemicalSubstance Ala-Thr zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74390 chebi_ph7_3 CL:0002598 biolink:Cell bronchial smooth muscle cell go-plus.json http://purl.obolibrary.org/obo/CL_0002598 CHEBI:74392 biolink:ChemicalSubstance Gly-Gln zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74392 chebi_ph7_3 CHEBI:74391 biolink:ChemicalSubstance Gly-Asn zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74391 chebi_ph7_3 CHEBI:74394 biolink:ChemicalSubstance Met-Ala zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74394 chebi_ph7_3 CHEBI:74393 biolink:ChemicalSubstance Gly-Met zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74393 chebi_ph7_3 CHEBI:74396 biolink:ChemicalSubstance (9Z,11E)-octadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74396 CHEBI:74395 biolink:ChemicalSubstance (11E)-octadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74395 CL:0002591 biolink:Cell smooth muscle cell of the pulmonary artery A smooth muscle of the pulmonary artery. go-plus.json http://purl.obolibrary.org/obo/CL_0002591 GO:0106250 biolink:MolecularActivity DNA-binding transcription repressor activity, RNA polymerase III-specific A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III. go-plus.json http://purl.obolibrary.org/obo/GO_0106250 CHEBI:74398 biolink:ChemicalSubstance (9Z)-heptadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74398 CHEBI:74397 biolink:ChemicalSubstance heptadecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74397 CL:0002590 biolink:Cell smooth muscle cell of the brain vasculature A vascular associated smooth muscle cell of the brain vasculature. go-plus.json http://purl.obolibrary.org/obo/CL_0002590 CL:0002592 biolink:Cell smooth muscle cell of the coronary artery A smooth muscle cell of the coronary artery. go-plus.json http://purl.obolibrary.org/obo/CL_0002592 CHEBI:74399 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z,27Z)-3-oxotriacontapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74399 GO:0106254 biolink:MolecularActivity lipid sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0106254 GO:0047232 biolink:MolecularActivity galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP. MetaCyc:2.4.1.164-RXN|EC:2.4.1.164 go-plus.json uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase|UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047232 GO:0106253 biolink:BiologicalProcess positive regulation of DNA strand resection involved in replication fork processing Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing. go-plus.json http://purl.obolibrary.org/obo/GO_0106253 GO:0047231 biolink:MolecularActivity pyridoxine 5'-O-beta-D-glucosyltransferase activity Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP. MetaCyc:2.4.1.160-RXN|EC:2.4.1.160|KEGG_REACTION:R01912|RHEA:20177 go-plus.json UDP-glucose-pyridoxine glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity|uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity|UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047231 GO:0047230 biolink:MolecularActivity flavonol-3-O-glucoside L-rhamnosyltransferase activity Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP. EC:2.4.1.159|RHEA:22528|MetaCyc:2.4.1.159-RXN go-plus.json uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity http://purl.obolibrary.org/obo/GO_0047230 GO:0106251 biolink:MolecularActivity N4-acetylcytidine amidohydrolase activity Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate. RHEA:62932 go-plus.json http://purl.obolibrary.org/obo/GO_0106251 GO:0106258 biolink:MolecularActivity L-serine-phosphatidylcholine phosphatidyltransferase activity Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline. RHEA:45088 go-plus.json http://purl.obolibrary.org/obo/GO_0106258 GO:0106257 biolink:MolecularActivity glycerol-3-phosphate dehydrogenase [NADP+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = glycerone phosphate + NADH + H+. RHEA:11096 go-plus.json http://purl.obolibrary.org/obo/GO_0106257 GO:0106256 biolink:MolecularActivity hydroperoxy icosatetraenoate dehydratase activity A hydroperoxy icosatetraenoate <=> an oxoicosatetraenoate + H(2)O. EC:4.2.1.152|RHEA:55556 go-plus.json http://purl.obolibrary.org/obo/GO_0106256 GO:0106255 biolink:MolecularActivity hydroperoxy icosatetraenoate isomerase activity A hydroperoxy icosatetraenoate <=> a hydroxy epoxy icosatrienoate. EC:5.4.4.7|RHEA:55560 go-plus.json http://purl.obolibrary.org/obo/GO_0106255 GO:0047239 biolink:MolecularActivity hydroxymandelonitrile glucosyltransferase activity Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP. MetaCyc:2.4.1.178-RXN|RHEA:15961|EC:2.4.1.178|KEGG_REACTION:R02709 go-plus.json cyanohydrin glucosyltransferase activity|UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity|UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047239 GO:0047238 biolink:MolecularActivity glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP. Reactome:R-HSA-1971482|MetaCyc:2.4.1.175-RXN|Reactome:R-HSA-3595176|Reactome:R-HSA-9632033|EC:2.4.1.175|Reactome:R-HSA-1971487 go-plus.json UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyltransferase II activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity|glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|chondroitin synthase activity http://purl.obolibrary.org/obo/GO_0047238 GO:0106259 biolink:BiologicalProcess cell-to-cell migration in host The directional movement of a symbiont from one host cell to another. go-plus.json http://purl.obolibrary.org/obo/GO_0106259 GO:0047237 biolink:MolecularActivity glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP. RHEA:23464|MetaCyc:2.4.1.174-RXN|EC:2.4.1.174 go-plus.json glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyltransferase I activity|uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I|UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047237 GO:0047236 biolink:MolecularActivity methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP. MetaCyc:2.4.1.171-RXN|EC:2.4.1.171|RHEA:20205 go-plus.json cycasin synthase activity|UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity|UDPglucose-methylazoxymethanol glucosyltransferase activity|uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity|methyl-ONN-azoxymethanol glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047236 GO:0047235 biolink:MolecularActivity sucrose 6F-alpha-galactotransferase activity Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP. RHEA:10088|MetaCyc:2.4.1.167-RXN|EC:2.4.1.167 go-plus.json UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity|UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity|sucrose 6F-alpha-galactosyltransferase activity|uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity|sucrose 6(F)-alpha-galactosyltransferase activity|UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047235 GO:0047234 biolink:MolecularActivity raffinose-raffinose alpha-galactotransferase activity Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose. RHEA:14125|MetaCyc:2.4.1.166-RXN|EC:2.4.1.166 go-plus.json raffinose:raffinose alpha-D-galactosyltransferase activity|raffinose-raffinose alpha-galactosyltransferase activity|raffinose (raffinose donor) galactosyltransferase activity|raffinose-raffinose a-galactosyltransferase activity|raffinose:raffinose alpha-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047234 GO:0047233 biolink:MolecularActivity N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP. MetaCyc:2.4.1.165-RXN|EC:2.4.1.165|RHEA:13569 go-plus.json uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047233 CL:0002563 biolink:Cell intestinal epithelial cell An epithelial cell of the intestine. go-plus.json http://purl.obolibrary.org/obo/CL_0002563 CL:1000155 biolink:Cell Malpighian tubule stellate cell A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. go-plus.json Malpighian tubule Type II cell http://purl.obolibrary.org/obo/CL_1000155 GO:0106261 biolink:MolecularActivity tRNA uridine(34) acetyltransferase activity Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H(+) + L-methionine. RHEA:61020 go-plus.json http://purl.obolibrary.org/obo/GO_0106261 GO:0106260 biolink:MolecularActivity DNA-DNA tethering activity Bridging together two regions of a DNA molecule. go-plus.json double-stranded DNA bridging|dsDNA bridging http://purl.obolibrary.org/obo/GO_0106260 GO:0047243 biolink:MolecularActivity flavanone 7-O-beta-glucosyltransferase activity Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP. MetaCyc:2.4.1.185-RXN|EC:2.4.1.185 go-plus.json UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity|naringenin 7-O-glucosyltransferase activity|UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity|hesperetin 7-O-glucosyl-transferase activity http://purl.obolibrary.org/obo/GO_0047243 GO:0106265 biolink:MolecularActivity THPH synthase activity Catalysis of the reaction: 3 H+ + hexanoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxyphenylhexan-1-one + 3 CO2 + 4 CoA. RHEA:64352 go-plus.json polyketide syntase http://purl.obolibrary.org/obo/GO_0106265 GO:0047242 biolink:MolecularActivity hydroxyanthraquinone glucosyltransferase activity Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP. MetaCyc:2.4.1.181-RXN|EC:2.4.1.181 go-plus.json UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity|uridine diphosphoglucose-anthraquinone glucosyltransferase activity|anthraquinone-specific glucosyltransferase activity|UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047242 GO:0106264 biolink:MolecularActivity protein serine kinase activity (using GTP as donor) Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H(+) + O-phospho-L-seryl-[protein]. RHEA:64020 go-plus.json http://purl.obolibrary.org/obo/GO_0106264 GO:0106263 biolink:MolecularActivity 1-acylglycerophosphoserine O-acyltransferase activity Catalysis of the reaction:a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA. RHEA:33191 go-plus.json http://purl.obolibrary.org/obo/GO_0106263 GO:0047241 biolink:MolecularActivity lipopolysaccharide N-acetylmannosaminouronosyltransferase activity Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP. RHEA:28366|MetaCyc:2.4.1.180-RXN|EC:2.4.1.180 go-plus.json ManNAcA transferase activity|LPS N-acetylmannosaminouronosyltransferase activity|uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity|UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity http://purl.obolibrary.org/obo/GO_0047241 GO:0047240 biolink:MolecularActivity lactosylceramide beta-1,3-galactosyltransferase activity Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP. MetaCyc:2.4.1.179-RXN|KEGG_REACTION:R04431|RHEA:18413|EC:2.4.1.179 go-plus.json UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity|uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity|UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0047240 GO:0106262 biolink:MolecularActivity 1-acylglycerophosphoethanolamine O-acyltransferase activity Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA. RHEA:32995 go-plus.json http://purl.obolibrary.org/obo/GO_0106262 GO:0106268 biolink:MolecularActivity 3,5-dichloro-THPH methyl transferase activity Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine. RHEA:48396 go-plus.json DIF-1 syntase http://purl.obolibrary.org/obo/GO_0106268 GO:0106267 biolink:MolecularActivity 3,5 dichloro-THPH synthase activity Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O. RHEA:64360 go-plus.json http://purl.obolibrary.org/obo/GO_0106267 UBERON:0036242 biolink:AnatomicalEntity post-embryonic notochord A notochord that has persisted beyond the embryonic stage. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036242 GO:0106266 biolink:MolecularActivity 3-chloro THPH synthase activity Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O. RHEA:64356 go-plus.json http://purl.obolibrary.org/obo/GO_0106266 UBERON:0012292 biolink:AnatomicalEntity embryonic cloacal fold One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly go-plus.json cloacal fold http://purl.obolibrary.org/obo/UBERON_0012292 UBERON:0012299 biolink:AnatomicalEntity mucosa of urethra A mucosa that is part of a urethra. go-plus.json tunica mucosa urethrae|mucous membrane of urethra|urethral mucosa http://purl.obolibrary.org/obo/UBERON_0012299 UBERON:0036244 biolink:AnatomicalEntity secretion of serous membrane A transudate found in the serous sac. go-plus.json serous sac fluid|serous fluid http://purl.obolibrary.org/obo/UBERON_0036244 UBERON:0036243 biolink:AnatomicalEntity vaginal fluid Fluid that lines the vaginal walls that consists of multiple secretions that collect in the vagina from different glands. go-plus.json vaginal discharge|vaginal secretion http://purl.obolibrary.org/obo/UBERON_0036243 GO:0047249 biolink:MolecularActivity sarsapogenin 3-beta-glucosyltransferase activity Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP. KEGG_REACTION:R04359|RHEA:14461|MetaCyc:2.4.1.193-RXN|EC:2.4.1.193 go-plus.json UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|sarsapogenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-sarsapogenin glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047249 UBERON:0036245 biolink:AnatomicalEntity parenchyma of mammary gland Parenchymal tissue that consists of the alveoli, grape-like clusters where milk is stored, and branching ducts, which are tubular canals carrying gladular secretions. go-plus.json parenchyma of lactiferous gland|mammary gland parenchyma|lactiferous gland parenchyma http://purl.obolibrary.org/obo/UBERON_0036245 GO:0047248 biolink:MolecularActivity nuatigenin 3-beta-glucosyltransferase activity Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP. KEGG_REACTION:R04577|RHEA:19329|MetaCyc:2.4.1.192-RXN|EC:2.4.1.192 go-plus.json UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity|nuatigenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-nuatigenin glucosyltransferase activity|UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047248 GO:0047247 biolink:MolecularActivity luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP. EC:2.4.1.191|KEGG_REACTION:R06828|RHEA:22116|MetaCyc:2.4.1.191-RXN go-plus.json uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity|UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|LDT|UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity|UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity http://purl.obolibrary.org/obo/GO_0047247 UBERON:0036248 biolink:AnatomicalEntity joint of auditory ossicle Any synovial joint that connects auditory ossicles. go-plus.json auditory ossicle joint|joint of auditory ossicles|auditory ossicles joint http://purl.obolibrary.org/obo/UBERON_0036248 GO:0047246 biolink:MolecularActivity luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP. EC:2.4.1.190|KEGG_REACTION:R06827|RHEA:14149|MetaCyc:2.4.1.190-RXN go-plus.json uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity|LMT activity|UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity|luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0047246 GO:0047245 biolink:MolecularActivity N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP. RHEA:20952|MetaCyc:2.4.1.188-RXN|EC:2.4.1.188 go-plus.json uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity|UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity|UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity|UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0047245 GO:0047244 biolink:MolecularActivity N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP. MetaCyc:TEICHOICSYN2-RXN|RHEA:16053|EC:2.4.1.187 go-plus.json uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity|N-acetylmannosaminyltransferase activity|UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity|UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0047244 CL:0002573 biolink:Cell Schwann cell A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. go-plus.json http://purl.obolibrary.org/obo/CL_0002573 CL:1000147 biolink:Cell heart valve cell go-plus.json http://purl.obolibrary.org/obo/CL_1000147 CL:0002575 biolink:Cell central nervous system pericyte A pericyte of the central nervous system. go-plus.json http://purl.obolibrary.org/obo/CL_0002575 CL:0002574 biolink:Cell stromal cell of pancreas A stromal cell of the pancreas. go-plus.json http://purl.obolibrary.org/obo/CL_0002574 CL:0002577 biolink:Cell placental epithelial cell An epithelial cell of the placenta. go-plus.json http://purl.obolibrary.org/obo/CL_0002577 CL:1000143 biolink:Cell lung goblet cell go-plus.json http://purl.obolibrary.org/obo/CL_1000143 GO:0106272 biolink:BiologicalProcess protein localization to ERGIC A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC). go-plus.json http://purl.obolibrary.org/obo/GO_0106272 GO:0106271 biolink:MolecularActivity D-arabinose 1-dehydrogenase (NADP+) activity Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH. RHEA:21892|EC:1.1.1.117 go-plus.json http://purl.obolibrary.org/obo/GO_0106271 CL:0002571 biolink:Cell hepatic mesenchymal stem cell A mesenchymal stem cell of liver. go-plus.json http://purl.obolibrary.org/obo/CL_0002571 CL:0002570 biolink:Cell mesenchymal stem cell of adipose A mesenchymal stem cell of adipose tissue. go-plus.json http://purl.obolibrary.org/obo/CL_0002570 CHEBI:25336 biolink:ChemicalSubstance methylpropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_25336 CHEBI:49302 biolink:ChemicalSubstance 2-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49302 CHEBI:49305 biolink:ChemicalSubstance 5,6alpha-epoxy-5alpha-cholestan-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_49305 chebi_ph7_3 CHEBI:25333 biolink:ChemicalSubstance pretetramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25333 UBERON:0012321 biolink:AnatomicalEntity deep cervical artery The deep cervical artery (Profunda cervicalis) is an artery of the neck. go-plus.json profunda cervicalis http://purl.obolibrary.org/obo/UBERON_0012321 UBERON:0012320 biolink:AnatomicalEntity cervical artery An artery of the neck go-plus.json http://purl.obolibrary.org/obo/UBERON_0012320 CHEBI:64940 biolink:ChemicalSubstance inositol phosphophytoceramide (t18:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64940 chebi_ph7_3 CL:1000217 biolink:Cell growth plate cartilage chondrocyte go-plus.json http://purl.obolibrary.org/obo/CL_1000217 CHEBI:49301 biolink:ChemicalSubstance hydrindane go-plus.json http://purl.obolibrary.org/obo/CHEBI_49301 chebi_ph7_3 UBERON:0012317 biolink:AnatomicalEntity vagina orifice The median slit located inferior and posterior to the external urethral orifice in the female; the exit for menstrual flow and birth and the entrance for the penis during sexual intercourse; the size and appearance of the vaginal orifice varies inversely with that of the hymen (G. membrane), a thin fold of mucous membrane that surrounds the vaginal orifice go-plus.json introitus of vagina|vagina opening|vaginal orifice|ostium vaginae|orifice of vagina|introitus|introitus|opening of vagina|vaginal introitus http://purl.obolibrary.org/obo/UBERON_0012317 UBERON:0012316 biolink:AnatomicalEntity primitive palate Roof of the buccal cavity, formed from the fusion of vomer, pterygoid, parasphenoid, palatine, ectopterygoid. go-plus.json palate http://purl.obolibrary.org/obo/UBERON_0012316 CHEBI:64942 biolink:ChemicalSubstance 3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64942 CHEBI:64941 biolink:ChemicalSubstance inositol phosphodihydroceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64941 chebi_ph7_3 CHEBI:64948 biolink:ChemicalSubstance pyrrolizidine alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64948 CHEBI:64947 biolink:ChemicalSubstance anti-HIV-1 agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_64947 CHEBI:64946 biolink:ChemicalSubstance anti-HIV agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_64946 CHEBI:64945 biolink:ChemicalSubstance sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64945 CHEBI:25347 biolink:ChemicalSubstance methyluridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25347 CHEBI:25345 biolink:ChemicalSubstance methyltetrahydrofolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25345 CHEBI:25348 biolink:ChemicalSubstance methylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25348 UBERON:0036301 biolink:AnatomicalEntity vasculature of spleen go-plus.json http://purl.obolibrary.org/obo/UBERON_0036301 UBERON:0012314 biolink:AnatomicalEntity embryonic facial prominence One of five swellings formed during the development of the face go-plus.json facial primordium|primordium of face|embryonic facial process http://purl.obolibrary.org/obo/UBERON_0012314 CHEBI:64951 biolink:ChemicalSubstance anti-HBV agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_64951 UBERON:0036303 biolink:AnatomicalEntity vasculature of central nervous system go-plus.json http://purl.obolibrary.org/obo/UBERON_0036303 CHEBI:64950 biolink:ChemicalSubstance pyrrolizidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64950 UBERON:0036302 biolink:AnatomicalEntity vasculature of central nervous system plus retina go-plus.json http://purl.obolibrary.org/obo/UBERON_0036302 UBERON:0012312 biolink:AnatomicalEntity maxillary process ectoderm go-plus.json http://purl.obolibrary.org/obo/UBERON_0012312 UBERON:0036304 biolink:AnatomicalEntity anatomical border An anatomical structure that is located along the line dividing two regions of an anatomical structure. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036304 CHEBI:25340 biolink:ChemicalSubstance methylpyridines go-plus.json http://purl.obolibrary.org/obo/CHEBI_25340 CHEBI:15999 biolink:ChemicalSubstance 4-hydroxyphenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15999 CHEBI:15998 biolink:ChemicalSubstance (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15998 CHEBI:40968 biolink:ChemicalSubstance astaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_40968 chebi_ph7_3 CHEBI:64953 biolink:ChemicalSubstance anti-HSV-1 agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_64953 CHEBI:64952 biolink:ChemicalSubstance anti-HSV agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_64952 CHEBI:64958 biolink:ChemicalSubstance N-(2-hydroxyhexacosanoyl)phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64958 chebi_ph7_3 CHEBI:15994 biolink:ChemicalSubstance 5alpha-androstane-3,17-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_15994 chebi_ph7_3 CHEBI:15997 biolink:ChemicalSubstance 2-methylpropanamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15997 CHEBI:15996 biolink:ChemicalSubstance GTP go-plus.json http://purl.obolibrary.org/obo/CHEBI_15996 CHEBI:64956 biolink:ChemicalSubstance sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64956 CHEBI:15993 biolink:ChemicalSubstance N-acyl-D-glucosamine 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15993 CHEBI:15992 biolink:ChemicalSubstance 1-hydroxy-2-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15992 chebi_ph7_3 CHEBI:25312 biolink:ChemicalSubstance 3-methylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25312 CHEBI:25311 biolink:ChemicalSubstance methylisocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25311 UBERON:0002979 biolink:AnatomicalEntity Purkinje cell layer of cerebellar cortex The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. go-plus.json reticulatum thalami (Hassler)|cerebellum Purkinje cell layer|nucleus reticulatus (thalami)|cerebellum Purkinje layer|reticular nucleus thalamus (Arnold)|cerebellar Purkinje cell layer|nucleus reticularis|nucleus thalamicus reticularis|Purkinje cell layer|nuclei reticulares (thalami) http://purl.obolibrary.org/obo/UBERON_0002979 CL:1000239 biolink:Cell anterior lateral line nerve glial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000239 CHEBI:64962 biolink:ChemicalSubstance glucobrassicin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64962 chebi_ph7_3 CHEBI:64961 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64961 CL:1000236 biolink:Cell posterior lateral line nerve glial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000236 NCBITaxon:166126 biolink:OrganismalEntity Seriata go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_166126 CHEBI:64964 biolink:ChemicalSubstance EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64964 CHEBI:64969 biolink:ChemicalSubstance inositol phosphodihydroceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64969 CHEBI:64967 biolink:ChemicalSubstance 4-carboxyzymosterol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64967 chebi_ph7_3 CHEBI:25324 biolink:ChemicalSubstance methylnaphthalenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_25324 CHEBI:25322 biolink:ChemicalSubstance methylmercury compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25322 UBERON:0002967 biolink:AnatomicalEntity cingulate gyrus One of the convolutions on the medial surface of the cerebral hemisphere. It surrounds the rostral part of the brain and interhemispheric commissure and forms part of the limbic system. (MSH) One of three essential structures comprising the limbic lobe, the other two being the hippocampus and parahippocampal gyrus. (CSP) go-plus.json cingulate region|gyri cinguli|cingulate area|falciform lobe|upper limbic gyrus|cingular gyrus http://purl.obolibrary.org/obo/UBERON_0002967 CHEBI:64973 biolink:ChemicalSubstance bicyclic nitroimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_64973 CHEBI:64971 biolink:ChemicalSubstance ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64971 chebi_ph7_3 CHEBI:64970 biolink:ChemicalSubstance inositol phosphophytoceramide (t18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64970 CHEBI:64977 biolink:ChemicalSubstance cichorine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64977 chebi_ph7_3 CHEBI:64976 biolink:ChemicalSubstance ergosteryl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64976 chebi_ph7_3 PR:000012705 biolink:Protein polymeric immunoglobulin receptor A protein that is a translation product of the human PIGR gene or a 1:1 ortholog thereof. go-plus.json PIGR|PIgR|poly-Ig receptor|hepatocellular carcinoma-associated protein TB6 http://purl.obolibrary.org/obo/PR_000012705 CL:1000223 biolink:Cell lung neuroendocrine cell go-plus.json http://purl.obolibrary.org/obo/CL_1000223 CHEBI:64975 biolink:ChemicalSubstance lanosteryl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64975 chebi_ph7_3 CL:1000222 biolink:Cell stomach neuroendocrine cell go-plus.json http://purl.obolibrary.org/obo/CL_1000222 CHEBI:64974 biolink:ChemicalSubstance (-)-microperfuranone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64974 chebi_ph7_3 UBERON:0002973 biolink:AnatomicalEntity parahippocampal gyrus Component of the temporal lobe on the mesial surface, posterior to the entorhinal cortex. The rostral and caudal boundaries are the posterior end of the netorhinal cortex and the caudal portion of the hippocampus, respectively. The medial boudnary is designated as the medial aspect off the temporal lobe and the lateral boundary is the collateral sulcus (Christine Fennema-Notestine). go-plus.json gyrus parahippocampalis|hippocampal gyrus|gyrus parahippocampi|gyrus hippocampi|hippocampal convolution http://purl.obolibrary.org/obo/UBERON_0002973 UBERON:0002974 biolink:AnatomicalEntity molecular layer of cerebellar cortex The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells go-plus.json thalamic fiber tracts|fasciculi thalami|cerebellum molecular cell layer|cerebellum molecular layer|cerebellar molecular layer|stratum moleculare corticis cerebelli http://purl.obolibrary.org/obo/UBERON_0002974 GO:0106078 biolink:MolecularActivity histone succinyltransferase activity Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone. go-plus.json http://purl.obolibrary.org/obo/GO_0106078 GO:0106077 biolink:BiologicalProcess histone succinylation The modification of a histone by the addition of an succinyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0106077 GO:0106076 biolink:MolecularActivity peptide-lysine-N-succinyltransferase activity Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0106076 CHEBI:74305 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74305 chebi_ph7_3 GO:0106075 biolink:MolecularActivity peptide N-succinyltransferase activity Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0106075 CHEBI:74304 biolink:ChemicalSubstance (6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74304 chebi_ph7_3 CHEBI:74307 biolink:ChemicalSubstance heptadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74307 chebi_ph7_3 UBERON:0012361 biolink:AnatomicalEntity internal anal region go-plus.json http://purl.obolibrary.org/obo/UBERON_0012361 CHEBI:74306 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74306 chebi_ph7_3 UBERON:0012360 biolink:AnatomicalEntity bone of jaw A bone element that is part of a jaw region. go-plus.json jaw bone http://purl.obolibrary.org/obo/UBERON_0012360 CHEBI:74309 biolink:ChemicalSubstance pentadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74309 chebi_ph7_3 CHEBI:74308 biolink:ChemicalSubstance (9Z)-heptadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74308 chebi_ph7_3 CHEBI:64980 biolink:ChemicalSubstance gammaGluCys(IAN)Gly go-plus.json http://purl.obolibrary.org/obo/CHEBI_64980 UBERON:0012367 biolink:AnatomicalEntity muscle layer of intestine A muscle layer that is part of an intestine. go-plus.json smooth muscle of intestine|muscularis externa of intestine|intestinal muscularis propria http://purl.obolibrary.org/obo/UBERON_0012367 CHEBI:64982 biolink:ChemicalSubstance 2-acyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64982 chebi_ph7_3 CHEBI:64981 biolink:ChemicalSubstance gammaGluCys(IAN)Gly(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64981 chebi_ph7_3 CHEBI:15966 biolink:ChemicalSubstance D-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15966 CHEBI:64988 biolink:ChemicalSubstance L-Cys(IAN) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64988 CHEBI:15965 biolink:ChemicalSubstance D-hexose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15965 CHEBI:64987 biolink:ChemicalSubstance S-conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64987 CHEBI:15968 biolink:ChemicalSubstance 3-guanidinopropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15968 UBERON:0012359 biolink:AnatomicalEntity pedal digitopodium bone A bone that is part of a the pedal digitopodium skeleton - i.e. the toes or the metatarsal skeleton. go-plus.json bone of hindlimb digitopodium http://purl.obolibrary.org/obo/UBERON_0012359 CHEBI:64985 biolink:ChemicalSubstance bioconjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64985 CHEBI:15961 biolink:ChemicalSubstance O-phospho-L-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15961 CHEBI:15964 biolink:ChemicalSubstance cyclohexylsulfamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15964 CHEBI:15963 biolink:ChemicalSubstance ribitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15963 chebi_ph7_3 GO:0106081 biolink:BiologicalProcess maltose import across plasma membrane The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0106081 GO:0106080 biolink:MolecularActivity GATOR1 complex binding Binding to a GATOR1 complex. go-plus.json http://purl.obolibrary.org/obo/GO_0106080 CHEBI:15960 biolink:ChemicalSubstance O-acetylcarnitinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_15960 GO:0106084 biolink:CellularComponent mitotic nuclear membrane microtubule tethering complex A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane. go-plus.json Mps2-Bbp1-Spc29 complex|nuclear membrane mitotic spindle pole body tethering complex http://purl.obolibrary.org/obo/GO_0106084 GO:0106083 biolink:CellularComponent nuclear membrane protein complex Any protein complex that is part of the nuclear membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0106083 CHEBI:74301 biolink:ChemicalSubstance wybutosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74301 GO:0106082 biolink:BiologicalProcess sucrose import across plasma membrane The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0106082 CHEBI:74300 biolink:ChemicalSubstance wybutosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74300 GO:0106089 biolink:BiologicalProcess negative regulation of cell adhesion involved in sprouting angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106089 GO:0106088 biolink:BiologicalProcess regulation of cell adhesion involved in sprouting angiogenesis Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106088 CHEBI:25302 biolink:ChemicalSubstance methyl glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_25302 CHEBI:74313 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z,24Z,27Z)-3-oxotriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74313 chebi_ph7_3 CHEBI:74316 biolink:ChemicalSubstance (14Z,17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74316 chebi_ph7_3 CHEBI:74315 biolink:ChemicalSubstance (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74315 chebi_ph7_3 CHEBI:74318 biolink:ChemicalSubstance (16Z,19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74318 chebi_ph7_3 CHEBI:25307 biolink:ChemicalSubstance methylguanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25307 CHEBI:74317 biolink:ChemicalSubstance (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74317 chebi_ph7_3 CHEBI:74319 biolink:ChemicalSubstance (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74319 chebi_ph7_3 UBERON:0012354 biolink:AnatomicalEntity acropodium region The segment of the autopod that is distal to the metapodial region and consists of the digits. go-plus.json set of digits|acropodial segment of autopod|acropodial region|acropodial limb segment http://purl.obolibrary.org/obo/UBERON_0012354 CHEBI:64991 biolink:ChemicalSubstance mannosylinositol phosphophytoceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64991 chebi_ph7_3 UBERON:0012353 biolink:AnatomicalEntity fin skeleton Skeletal subdivision consisting of all the skeletal elements in a single fin. go-plus.json skeleton of fin http://purl.obolibrary.org/obo/UBERON_0012353 CHEBI:39949 biolink:ChemicalSubstance triphosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39949 UBERON:0012358 biolink:AnatomicalEntity manual digitopodium bone A bone that is part of a the manual digitopodium skeleton - i.e. the fingers or the metacarpal skeleton. go-plus.json bone of forelimb digitopodium http://purl.obolibrary.org/obo/UBERON_0012358 CHEBI:64995 biolink:ChemicalSubstance EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64995 UBERON:0012357 biolink:AnatomicalEntity digitopodium bone A bone that is part of a the digitopodium skeleton - i.e. the acropodial skeleton or the metapodial skeleton. go-plus.json digit bone http://purl.obolibrary.org/obo/UBERON_0012357 CHEBI:64994 biolink:ChemicalSubstance inositol phosphophytoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64994 CHEBI:15958 biolink:ChemicalSubstance phosphatidyl-N-methylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15958 UBERON:0012356 biolink:AnatomicalEntity pedal acropodium region The segment of the pes that is distal to the metatarsal region and consists of the pedal digits (toes). go-plus.json acropodial region of pes|toes set|all toes|toes|digits of foot|acropodial segment of pes|set of toes|acropodial forelimb segment|pedal acropodium region http://purl.obolibrary.org/obo/UBERON_0012356 CHEBI:64993 biolink:ChemicalSubstance inositol phosphophytoceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64993 chebi_ph7_3 UBERON:0012355 biolink:AnatomicalEntity manual acropodium region The segment of the manus that is distal to the metacarpal region and consists of the manual digits (fingers). go-plus.json anterior acropodium segment of limb|anterior acropodium region|manual acropodium|acropodial segment of manus|acropodial hindlimb segment|fingers set|all fingers|set of digits of hand|acropodial region of manus|fingers including thumb|manual acropodium segment of limb|set of fingers|manual acropodium region|digits of hand|anterior acropodium|digiti manus http://purl.obolibrary.org/obo/UBERON_0012355 CHEBI:64992 biolink:ChemicalSubstance inositol phosphomannosylinositol phosphophytoceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64992 chebi_ph7_3 CHEBI:15955 biolink:ChemicalSubstance discadenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15955 CHEBI:64999 biolink:ChemicalSubstance 3,3'-bipyridine-2,2',5,5',6,6'-hexol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64999 chebi_ph7_3 CHEBI:64998 biolink:ChemicalSubstance nicotine blue(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64998 chebi_ph7_3 CHEBI:15954 biolink:ChemicalSubstance aldehydo-D-glucose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15954 CHEBI:15957 biolink:ChemicalSubstance stipitatic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15957 CHEBI:64997 biolink:ChemicalSubstance mannosylinositol phosphorylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64997 chebi_ph7_3 CHEBI:15956 biolink:ChemicalSubstance biotin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15956 CHEBI:64996 biolink:ChemicalSubstance EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64996 CHEBI:15951 biolink:ChemicalSubstance 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_15951 chebi_ph7_3 CHEBI:15950 biolink:ChemicalSubstance (S)-coclaurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15950 CHEBI:15953 biolink:ChemicalSubstance 6-imino-5-oxocyclohexa-1,3-dienecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15953 CHEBI:15952 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15952 GO:0106092 biolink:BiologicalProcess glial cell projection elongation involved in axon ensheathment The extension of a glial cell process or projection to wrap around an axon. go-plus.json http://purl.obolibrary.org/obo/GO_0106092 GO:0106091 biolink:BiologicalProcess glial cell projection elongation The process of creating an elongation or projection from a glial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0106091 GO:0106090 biolink:BiologicalProcess positive regulation of cell adhesion involved in sprouting angiogenesis Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0106090 GO:0106096 biolink:BiologicalProcess response to ceramide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0106096 CHEBI:74310 biolink:ChemicalSubstance (9Z)-pentadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74310 chebi_ph7_3 GO:0106095 biolink:CellularComponent m7G(5')pppN diphosphatase complex A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide. go-plus.json m7G(5')pppN pyrophosphatase enzyme|m7G(5')pppN diphosphatase enzyme|DCS1 decapping scavenger complex|7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase enzyme|M(7)G(5')pppN pyrophosphatase enzyme http://purl.obolibrary.org/obo/GO_0106095 GO:0106094 biolink:CellularComponent nuclear membrane microtubule tethering complex A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0106094 CHEBI:74312 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74312 chebi_ph7_3 CHEBI:74311 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z,22Z,25Z)-3-oxooctacosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74311 chebi_ph7_3 GO:0106093 biolink:CellularComponent EDS1 disease-resistance complex A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes. go-plus.json EDS1-PAD4-SAG101 complex|EDS1-PAD4 complex|EDS1-SAG101 complex http://purl.obolibrary.org/obo/GO_0106093 GO:0106099 biolink:MolecularActivity 2-keto-3-deoxy-L-rhamnonate aldolase activity Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde. EC:4.1.2.53|RHEA:25784 go-plus.json http://purl.obolibrary.org/obo/GO_0106099 CHEBI:74324 biolink:ChemicalSubstance L-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_74324 GO:0106098 biolink:CellularComponent NAGS/NAGK complex A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106098 GO:0106097 biolink:BiologicalProcess cellular response to ceramide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0106097 CHEBI:74329 biolink:ChemicalSubstance (13Z,16Z,19Z)-3-oxodocosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74329 chebi_ph7_3 CHEBI:74328 biolink:ChemicalSubstance (11Z,14Z,17Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74328 chebi_ph7_3 UBERON:0012344 biolink:AnatomicalEntity holocrine gland any exocrine gland whose secretion consists of its own disintegrated secretory cells along with its secretory product; holocrine secretions are produced in the cytoplasm of the cell and released by the rupture of the plasma membrane, which destroys the cell and results in the secretion of the product into the lumen. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012344 CHEBI:40910 biolink:ChemicalSubstance azide anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_40910 chebi_ph7_3 CHEBI:15987 biolink:ChemicalSubstance trithionate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15987 chebi_ph7_3 CHEBI:15989 biolink:ChemicalSubstance L-methionine S-oxide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_15989 chebi_ph7_3 CHEBI:15984 biolink:ChemicalSubstance N-(4-nitrophenyl)-3-oxovalidamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15984 chebi_ph7_3 CHEBI:15986 biolink:ChemicalSubstance polynucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15986 CHEBI:15980 biolink:ChemicalSubstance (R)-pantoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15980 chebi_ph7_3 CHEBI:15982 biolink:ChemicalSubstance cob(I)alamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15982 CHEBI:15981 biolink:ChemicalSubstance heparan sulfate alpha-D-glucosaminide 3-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15981 CHEBI:74320 biolink:ChemicalSubstance (18Z,21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74320 chebi_ph7_3 CHEBI:74322 biolink:ChemicalSubstance 4,8,12-trimethyltrideca 1,3,7,11-tetraene go-plus.json http://purl.obolibrary.org/obo/CHEBI_74322 chebi_ph7_3 CHEBI:74335 biolink:ChemicalSubstance 1-acyl-2-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74335 chebi_ph7_3 CHEBI:74338 biolink:ChemicalSubstance D-valine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74338 chebi_ph7_3 CHEBI:74337 biolink:ChemicalSubstance D-asparagine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74337 chebi_ph7_3 CHEBI:74339 biolink:ChemicalSubstance (6Z)-hexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74339 chebi_ph7_3 GO:0047405 biolink:MolecularActivity pyrimidine-5'-nucleotide nucleosidase activity Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine. MetaCyc:3.2.2.10-RXN|EC:3.2.2.10|RHEA:13425 go-plus.json Pyr5N activity|pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity|pyrimidine nucleotide N-ribosidase activity http://purl.obolibrary.org/obo/GO_0047405 UBERON:0012332 biolink:AnatomicalEntity broad ligament of uterus A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis. go-plus.json broad ligament|broad uterine ligament|ligamentum latum uteri http://purl.obolibrary.org/obo/UBERON_0012332 GO:0047404 biolink:MolecularActivity glucuronosyl-disulfoglucosamine glucuronidase activity Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine. MetaCyc:3.2.1.56-RXN|RHEA:15073|EC:3.2.1.56 go-plus.json glucuronosyl-disulphoglucosamine glucuronidase activity|3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity|3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity http://purl.obolibrary.org/obo/GO_0047404 UBERON:0012330 biolink:AnatomicalEntity nasal-associated lymphoid tissue The lymphocytic cell population present in the mucosa of the nasopharyngeal duct of some animals. go-plus.json NALT|naso-pharyngeal lymphoid tissue http://purl.obolibrary.org/obo/UBERON_0012330 GO:0047403 biolink:MolecularActivity lacto-N-biosidase activity Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc. EC:3.2.1.140|RHEA:21568 go-plus.json oligosaccharide lacto-N-biosylhydrolase activity http://purl.obolibrary.org/obo/GO_0047403 GO:0047402 biolink:MolecularActivity protein-glucosylgalactosylhydroxylysine glucosidase activity Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins. EC:3.2.1.107|MetaCyc:3.2.1.107-RXN|RHEA:11068 go-plus.json 2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity|protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity http://purl.obolibrary.org/obo/GO_0047402 GO:0047401 biolink:MolecularActivity trithionate hydrolase activity Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate. EC:3.12.1.1|MetaCyc:3.12.1.1-RXN|KEGG_REACTION:R01930|RHEA:21884 go-plus.json trithionate thiosulfohydrolase activity http://purl.obolibrary.org/obo/GO_0047401 GO:0047400 biolink:MolecularActivity phosphonoacetate hydrolase activity Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate. EC:3.11.1.2|KEGG_REACTION:R00318|RHEA:16749|MetaCyc:3.11.1.2-RXN go-plus.json phosphonoacetate phosphonohydrolase activity http://purl.obolibrary.org/obo/GO_0047400 CHEBI:15977 biolink:ChemicalSubstance cyclohex-2-enone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15977 chebi_ph7_3 UBERON:0012329 biolink:AnatomicalEntity keratinized stratified squamous epithelium Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin. go-plus.json epithelium stratificatum squamosum cornificatum http://purl.obolibrary.org/obo/UBERON_0012329 CHEBI:15976 biolink:ChemicalSubstance 3-indoleglycolaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15976 chebi_ph7_3 CHEBI:15979 biolink:ChemicalSubstance 1-benzyl-2-methyl-1,2,3,4-tetrahydroisoquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_15979 CHEBI:15978 biolink:ChemicalSubstance sn-glycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15978 GO:0047409 biolink:MolecularActivity alkenylglycerophosphoethanolamine hydrolase activity Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde. MetaCyc:3.3.2.5-RXN|EC:3.3.2.5|RHEA:16905 go-plus.json 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity http://purl.obolibrary.org/obo/GO_0047409 GO:0047408 biolink:MolecularActivity alkenylglycerophosphocholine hydrolase activity Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde. MetaCyc:3.3.2.2-RXN|EC:3.3.2.2|RHEA:22544 go-plus.json lysoplasmalogenase activity|1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity http://purl.obolibrary.org/obo/GO_0047408 CHEBI:15972 biolink:ChemicalSubstance dTDP-4-amino-4,6-dideoxy-D-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15972 CHEBI:15975 biolink:ChemicalSubstance 1D-5-O-methyl-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15975 chebi_ph7_3 GO:0047407 biolink:MolecularActivity ADP-ribosyl-[dinitrogen reductase] hydrolase activity Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase]. RHEA:14493|MetaCyc:3.2.2.24-RXN|EC:3.2.2.24 go-plus.json ADP-ribosyl-dinitrogen reductase hydrolase activity|azoferredoxin-activating enzymes|ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity|azoferredoxin glycosidase activity|dinitrogenase reductase-activating glycohydrolase activity|ADP-ribosyl glycohydrolase activity|dinitrogenase reductase activating glycohydrolase activity http://purl.obolibrary.org/obo/GO_0047407 GO:0047406 biolink:MolecularActivity beta-aspartyl-N-acetylglucosaminidase activity Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine. KEGG_REACTION:R01266|MetaCyc:3.2.2.11-RXN|EC:3.2.2.11|RHEA:12324 go-plus.json beta-aspartylacetylglucosaminidase activity|1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity http://purl.obolibrary.org/obo/GO_0047406 CHEBI:15971 biolink:ChemicalSubstance L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15971 CHEBI:15970 biolink:ChemicalSubstance O-carbamoyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15970 CHEBI:74334 biolink:ChemicalSubstance (10Z,13Z,16Z,19Z)-3-oxodocosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74334 chebi_ph7_3 UBERON:0002916 biolink:AnatomicalEntity central sulcus The central sulcus is a fold in the cerebral cortex of brains in vertebrates. Also called the central fissure, it was originally called the fissure of Rolando or the Rolandic fissure, after Luigi Rolando. The central sulcus is a prominent landmark of the brain, separating the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex. [WP,unvetted]. go-plus.json rolandic fissure|sulcus of Rolando|sulcus centralis (rolandi)|CS|central cerebral sulcus|central sulcus of Rolando|central fissure|sulcus centralis cerebri|fissure of Rolando|sulcus centralis http://purl.obolibrary.org/obo/UBERON_0002916 CHEBI:49388 biolink:ChemicalSubstance bacterioruberin go-plus.json http://purl.obolibrary.org/obo/CHEBI_49388 chebi_ph7_3 CHEBI:50372 biolink:ChemicalSubstance (S)-rosmarinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50372 CHEBI:50371 biolink:ChemicalSubstance (R)-rosmarinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50371 CHEBI:50370 biolink:ChemicalSubstance parasympatholytic go-plus.json http://purl.obolibrary.org/obo/CHEBI_50370 CHEBI:50375 biolink:ChemicalSubstance dihydromethanophenazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50375 chebi_ph7_3 CHEBI:50367 biolink:ChemicalSubstance taxane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50367 CHEBI:50361 biolink:ChemicalSubstance ketolactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50361 CHEBI:50360 biolink:ChemicalSubstance (-)-1,2-campholide go-plus.json http://purl.obolibrary.org/obo/CHEBI_50360 chebi_ph7_3 CHEBI:25399 biolink:ChemicalSubstance cresol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25399 CHEBI:25392 biolink:ChemicalSubstance naphthols go-plus.json http://purl.obolibrary.org/obo/CHEBI_25392 CHEBI:132623 biolink:ChemicalSubstance nodakenetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_132623 chebi_ph7_3 CHEBI:50351 biolink:ChemicalSubstance cyclopropanecarboxylate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_50351 CHEBI:50347 biolink:ChemicalSubstance L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50347 chebi_ph7_3 CHEBI:50349 biolink:ChemicalSubstance D-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50349 chebi_ph7_3 CHEBI:50348 biolink:ChemicalSubstance L-asparaginyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50348 chebi_ph7_3 CHEBI:50342 biolink:ChemicalSubstance L-proline residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50342 chebi_ph7_3 CHEBI:50341 biolink:ChemicalSubstance 1-hydroxyethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50341 chebi_ph7_3 CHEBI:50340 biolink:ChemicalSubstance 3-carbamimidamidopropyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50340 CHEBI:50336 biolink:ChemicalSubstance 4-hydroxybenzyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50336 chebi_ph7_3 CHEBI:50335 biolink:ChemicalSubstance organic nitrogen anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_50335 CHEBI:50334 biolink:ChemicalSubstance pyridinium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_50334 CHEBI:50339 biolink:ChemicalSubstance 4-aminobutyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50339 CHEBI:50338 biolink:ChemicalSubstance 1H-imidazol-4-ylmethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50338 chebi_ph7_3 UBERON:0002956 biolink:AnatomicalEntity granular layer of cerebellar cortex The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. go-plus.json cerebellum granule cell layer|cerebellar granular layer|granular layer of cerebellum|stratum granulosum cerebelli|cerebellum granule layer|stratum granulosum corticis cerebelli|cerebellar granule cell layer|granule cell layer of cerebellar cortex|cerebellar granule layer http://purl.obolibrary.org/obo/UBERON_0002956 CHEBI:50337 biolink:ChemicalSubstance 1H-indol-3-ylmethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50337 chebi_ph7_3 CHEBI:25372 biolink:ChemicalSubstance molybdopterin cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_25372 CHEBI:25371 biolink:ChemicalSubstance molybdic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25371 CHEBI:25370 biolink:ChemicalSubstance molybdenum molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_25370 CHEBI:25375 biolink:ChemicalSubstance monoamine molecular messenger go-plus.json http://purl.obolibrary.org/obo/CHEBI_25375 CHEBI:64900 biolink:ChemicalSubstance [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_64900 CHEBI:64908 biolink:ChemicalSubstance (3E)-2-oxohex-3-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64908 chebi_ph7_3 CHEBI:64907 biolink:ChemicalSubstance 2-aminoicosane-1,3-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64907 CHEBI:64905 biolink:ChemicalSubstance C20 sphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64905 CHEBI:50331 biolink:ChemicalSubstance 3-amino-3-oxopropyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50331 chebi_ph7_3 BSPO:0005001 biolink:OntologyClass intersects_midsagittal_plane_of X intersects_median_plane of iff X crosses the midine plane of Y. BSPO:0005001 go-plus.json http://purl.obolibrary.org/obo/BSPO_0005001 CHEBI:50330 biolink:ChemicalSubstance 2-amino-2-oxoethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50330 chebi_ph7_3 CHEBI:64909 biolink:ChemicalSubstance poison go-plus.json http://purl.obolibrary.org/obo/CHEBI_64909 CHEBI:50325 biolink:ChemicalSubstance proteinogenic amino-acid side-chain group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50325 CHEBI:50324 biolink:ChemicalSubstance guanosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50324 CHEBI:50323 biolink:ChemicalSubstance 2'-deoxyadenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50323 CHEBI:25389 biolink:ChemicalSubstance monohydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25389 UBERON:0002949 biolink:AnatomicalEntity tectospinal tract A long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord[GO]. go-plus.json Held's bundle|tectospinal pathway|tractus tectospinalis|tectospinal tract of the medulla|tectospinal tract|tectospinal pathway http://purl.obolibrary.org/obo/UBERON_0002949 CHEBI:25388 biolink:ChemicalSubstance monohydroxybenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25388 CHEBI:50322 biolink:ChemicalSubstance 2'-deoxyguanosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50322 UBERON:0002944 biolink:AnatomicalEntity spinothalamic tract of medulla Part of spinothalamic tract that is in the medulla go-plus.json spinothalamic tract|spinothalamic tract of the medulla|tractus spinothalamicus (myelencephali) http://purl.obolibrary.org/obo/UBERON_0002944 CHEBI:50329 biolink:ChemicalSubstance 2-carboxyethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50329 CHEBI:50327 biolink:ChemicalSubstance selanylmethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50327 chebi_ph7_3 CHEBI:50326 biolink:ChemicalSubstance sulfanylmethyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_50326 chebi_ph7_3 CHEBI:25381 biolink:ChemicalSubstance monoalkyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25381 CHEBI:25380 biolink:ChemicalSubstance acetylenic fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25380 CHEBI:25387 biolink:ChemicalSubstance monohydroxyacetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25387 CHEBI:25384 biolink:ChemicalSubstance monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25384 CHEBI:64911 biolink:ChemicalSubstance antimitotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_64911 CHEBI:64910 biolink:ChemicalSubstance C20 phytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64910 CHEBI:132610 biolink:ChemicalSubstance phthalic acid monoester go-plus.json http://purl.obolibrary.org/obo/CHEBI_132610 CHEBI:64915 biolink:ChemicalSubstance antiplasmodial drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_64915 CHEBI:64912 biolink:ChemicalSubstance antimycobacterial drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_64912 CHEBI:64919 biolink:ChemicalSubstance EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64919 CHEBI:64918 biolink:ChemicalSubstance C20 phytosphingosine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64918 CHEBI:64917 biolink:ChemicalSubstance C20 sphinganine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64917 CHEBI:64916 biolink:ChemicalSubstance inositol phosphoceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64916 chebi_ph7_3 CHEBI:50321 biolink:ChemicalSubstance 2'-deoxycytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50321 CHEBI:50320 biolink:ChemicalSubstance nucleoside residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50320 CHEBI:50314 biolink:ChemicalSubstance fluoronium go-plus.json http://purl.obolibrary.org/obo/CHEBI_50314 chebi_ph7_3 CHEBI:50313 biolink:ChemicalSubstance onium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_50313 CHEBI:25357 biolink:ChemicalSubstance mitomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25357 CHEBI:50312 biolink:ChemicalSubstance onium compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_50312 CHEBI:25355 biolink:ChemicalSubstance mitochondrial respiratory-chain inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_25355 CHEBI:50317 biolink:ChemicalSubstance iodonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_50317 chebi_ph7_3 DDANAT:0000414 biolink:OntologyClass spore Dormant cell protected by a tri-layer spore coat. The spore has an elliptical shape and is approximately 6-9 microns by 3 microns. go-plus.json spore cell http://purl.obolibrary.org/obo/DDANAT_0000414 CHEBI:50316 biolink:ChemicalSubstance bromonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_50316 chebi_ph7_3 CHEBI:50315 biolink:ChemicalSubstance chloronium go-plus.json http://purl.obolibrary.org/obo/CHEBI_50315 chebi_ph7_3 CHEBI:25350 biolink:ChemicalSubstance mevalonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25350 chebi_ph7_3 DDANAT:0000410 biolink:OntologyClass pstAB cell Cell that is undergoing differentiation to become a stalk cell. pstAB cells express both ecmA and ecmB either simultaneously or sequentially. During culmination pstA differentiate into pstAB cells. go-plus.json prestalk AB cell http://purl.obolibrary.org/obo/DDANAT_0000410 DDANAT:0000413 biolink:OntologyClass stalk cell Cell of polyhedric shape filling the stalk tube. Stack cells are large (around 8 microns in diameter), highly vacuolated, and are surrounded by cell wall composed of cellulose. Stalk cells die upon terminal differentiation. Their role is to provide structural support for the fruiting body. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000413 CHEBI:50319 biolink:ChemicalSubstance nucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50319 CHEBI:40992 biolink:ChemicalSubstance N-acetyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_40992 CHEBI:25354 biolink:ChemicalSubstance mineralocorticoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25354 CHEBI:49323 biolink:ChemicalSubstance contraceptive drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_49323 CHEBI:25351 biolink:ChemicalSubstance mevalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25351 CHEBI:49322 biolink:ChemicalSubstance anthracycline antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_49322 CHEBI:64921 biolink:ChemicalSubstance 3,4-dihydroxy-5-polyprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64921 CHEBI:64926 biolink:ChemicalSubstance serine protease inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64926 CHEBI:64925 biolink:ChemicalSubstance 4beta-methylzymosterol-4alpha-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64925 chebi_ph7_3 CHEBI:64928 biolink:ChemicalSubstance 2-oxohex-3-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64928 chebi_ph7_3 CHEBI:64927 biolink:ChemicalSubstance 2-oxohex-3-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64927 DDANAT:0000408 biolink:OntologyClass pstA cell Cell that is undergoing differentiation to become a stalk cell. pstA cells express the ecmA marker from a promoter region that is proximal to the ATG (ecmAO promoter). They are located at the anterior-most region of the slug. During culmination pstA cells differentiate into pstAB cells. go-plus.json prestalk A cell|pstAO cell http://purl.obolibrary.org/obo/DDANAT_0000408 UBERON:0002926 biolink:AnatomicalEntity gustatory epithelium A sensory epithelium that is part of a gustatory system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002926 CHEBI:50303 biolink:ChemicalSubstance terpentedienyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50303 CHEBI:49314 biolink:ChemicalSubstance germacrene B go-plus.json http://purl.obolibrary.org/obo/CHEBI_49314 CHEBI:50302 biolink:ChemicalSubstance terpentetriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50302 chebi_ph7_3 UBERON:0002925 biolink:AnatomicalEntity trigeminal nucleus A nucleus of brain that is part of a trigeminal nuclear complex. go-plus.json nucleus mesencephalicus nervi trigemini|trigeminal nuclear complex nucleus|trigeminal V nucleus|nucleus tractus mesencephali nervi trigeminalis|trigeminal nucleus|nucleus of trigeminal nuclear complex|nucleus mesencephalicus trigeminalis http://purl.obolibrary.org/obo/UBERON_0002925 UBERON:0002928 biolink:AnatomicalEntity dentate gyrus polymorphic layer A cellular layer of the dentate gyrus enclosed by the granule cell layer. A number of cell types are located in the polymorphic layer but the most prominent is the mossy cell. go-plus.json polymorph layer of the dentate gyrus|CA4 http://purl.obolibrary.org/obo/UBERON_0002928 CHEBI:25367 biolink:ChemicalSubstance molecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_25367 CHEBI:50300 biolink:ChemicalSubstance thymidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50300 CHEBI:49318 biolink:ChemicalSubstance piperidine antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_49318 CHEBI:50307 biolink:ChemicalSubstance furonaphthodioxole go-plus.json http://purl.obolibrary.org/obo/CHEBI_50307 UBERON:0002921 biolink:AnatomicalEntity longitudinal fissure The deep groove which separates the two hemispheres of the vertebrate brain. The falx cerebri, a dural brain covering, lies within the medial longitudinal fissure. [WP,unvetted]. go-plus.json longitudinal fissure of the cerebrum|sagittal fissure|hemispheric sulcus|longitudinal fissure of hemisphere|fissura longitudinalis magna|fissura longitudinalis cerebri|longitudinal sulcus|fissura longitudinalis cerebrales|longitudinal cerebral fissure|LF|fissura interhemispherica|medial longitudinal fissure|interhemispheric fissure http://purl.obolibrary.org/obo/UBERON_0002921 CHEBI:50306 biolink:ChemicalSubstance adenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50306 DDANAT:0000403 biolink:OntologyClass aggregate cell Differentiating cell composing the aggregate that has acquired adhesive properties. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000403 DDANAT:0000406 biolink:OntologyClass prestalk cell Cell that is undergoing differentiation to become a stalk cell and characterized by the ability to update vital dyes. Represents about one-quarter of the cells. During development, prestalk cells are located in the anterior portion of the organism. go-plus.json pst cell|anterior cell http://purl.obolibrary.org/obo/DDANAT_0000406 CHEBI:50305 biolink:ChemicalSubstance podophyllotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50305 chebi_ph7_3 DDANAT:0000405 biolink:OntologyClass prespore cell Cell that is undergoing differentiation to become a spore. Characterized by the presence of prespore vesicles (PV). go-plus.json psp cell http://purl.obolibrary.org/obo/DDANAT_0000405 CHEBI:49319 biolink:ChemicalSubstance carbocyclic antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_49319 DDANAT:0000402 biolink:OntologyClass chemotactic amoeboid cell Starved cell that secretes and responds to chemoattractants (cAMP). go-plus.json amoebae http://purl.obolibrary.org/obo/DDANAT_0000402 DDANAT:0000401 biolink:OntologyClass cell Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/DDANAT_0000401 CHEBI:50308 biolink:ChemicalSubstance cytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50308 CHEBI:49310 biolink:ChemicalSubstance 7-methylxanthosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_49310 chebi_ph7_3 CHEBI:49311 biolink:ChemicalSubstance alpha-humulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49311 chebi_ph7_3 CHEBI:25362 biolink:ChemicalSubstance elemental molecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_25362 CHEBI:64933 biolink:ChemicalSubstance melanin synthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64933 CHEBI:64931 biolink:ChemicalSubstance lysophosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64931 CHEBI:64930 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64930 CHEBI:64937 biolink:ChemicalSubstance 3-heptaprenyl-sn-glycero-1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64937 CHEBI:64936 biolink:ChemicalSubstance N(pros)-phospho-L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64936 CHEBI:64939 biolink:ChemicalSubstance 3,4-dihydro-4-hydroxyphenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64939 CHEBI:64938 biolink:ChemicalSubstance N(pros)-phospho-L-histidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64938 GO:0047375 biolink:MolecularActivity N-acetylgalactosaminoglycan deacetylase activity Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan. EC:3.1.1.58|MetaCyc:3.1.1.58-RXN go-plus.json Vi-polysaccharide deacetylase activity|N-acetyl-D-galactosaminoglycan acetylhydrolase activity|polysaccharide deacetylase activity|N-acetyl galactosaminoglycan deacetylase activity http://purl.obolibrary.org/obo/GO_0047375 GO:0072331 biolink:BiologicalProcess signal transduction by p53 class mediator An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein. go-plus.json http://purl.obolibrary.org/obo/GO_0072331 GO:0072330 biolink:BiologicalProcess monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. go-plus.json monocarboxylic acid biosynthesis|monocarboxylic acid anabolism|monocarboxylic acid synthesis|monocarboxylic acid formation http://purl.obolibrary.org/obo/GO_0072330 GO:0047374 biolink:MolecularActivity methylumbelliferyl-acetate deacetylase activity Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+). EC:3.1.1.56|RHEA:12208|KEGG_REACTION:R04141|MetaCyc:3.1.1.56-RXN go-plus.json esterase D activity|4-methylumbelliferyl-acetate acylhydrolase activity http://purl.obolibrary.org/obo/GO_0047374 GO:0047373 biolink:MolecularActivity acetoxybutynylbithiophene deacetylase activity Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+). RHEA:11548|EC:3.1.1.54|KEGG_REACTION:R04490|MetaCyc:3.1.1.54-RXN go-plus.json 5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity|5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity|acetoxybutynylbithiophene esterase activity http://purl.obolibrary.org/obo/GO_0047373 GO:0047372 biolink:MolecularActivity acylglycerol lipase activity Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. EC:3.1.1.23|RHEA:34019|Reactome:R-HSA-426032|Reactome:R-HSA-1482543|Reactome:R-HSA-192422|MetaCyc:3.1.1.23-RXN|Reactome:R-HSA-192430|Reactome:R-HSA-192475|Reactome:R-HSA-163595|Reactome:R-HSA-5694462|Reactome:R-HSA-426043|Reactome:R-HSA-192434|Reactome:R-HSA-192425 go-plus.json monoglyceride lipase activity|fatty acyl monoester lipase activity|monoglyceridase activity|monoacylglycerolipase activity|glycerol-ester acylhydrolase activity|monoglyceride hydrolase activity|monoacylglycerol hydrolase activity|monoglyceridyllipase activity|monoacylglycerol lipase activity http://purl.obolibrary.org/obo/GO_0047372 goslim_chembl GO:0047371 biolink:MolecularActivity butyrate-acetoacetate CoA-transferase activity Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate. MetaCyc:2.8.3.9-RXN|EC:2.8.3.9|KEGG_REACTION:R01365|RHEA:12961 go-plus.json butyryl coenzyme A-acetoacetate coenzyme A-transferase activity|butyryl-CoA-acetoacetate CoA-transferase activity|butanoyl-CoA:acetoacetate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0047371 GO:0047370 biolink:MolecularActivity succinate-citramalate CoA-transferase activity Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate. MetaCyc:2.8.3.7-RXN|RHEA:23528 go-plus.json succinyl coenzyme A-citramalyl coenzyme A transferase activity|succinyl-CoA:citramalate CoA-transferase activity|citramalate coenzyme A-transferase activity|itaconate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0047370 CL:0002427 biolink:Cell resting double-positive thymocyte A double-positive, alpha-beta thymocyte that is small and not proliferating. go-plus.json T.DP.sm.Th http://purl.obolibrary.org/obo/CL_0002427 CL:0002429 biolink:Cell CD69-positive double-positive thymocyte A double-positive thymocyte that is CD69-positive and has begun positive selection. go-plus.json T.DP69+.Th http://purl.obolibrary.org/obo/CL_0002429 CL:0002428 biolink:Cell double-positive blast A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating. go-plus.json activated double-positive thymocyte|T.DPb.Th http://purl.obolibrary.org/obo/CL_0002428 CHEBI:142058 biolink:ChemicalSubstance F2-isoprostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_142058 GO:0047379 biolink:MolecularActivity ADP-dependent short-chain-acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA. EC:3.1.2.18|MetaCyc:3.1.2.18-RXN go-plus.json ADP-dependent propionyl-CoA hydrolase activity|ADP-dependent short-chain acyl-CoA thioesterase activity|ADP-dependent propionyl-CoA thioesterase activity|ADP-dependent short-chain acyl coenzyme A hydrolase activity|ADP-dependent-short-chain-acyl-CoA hydrolase activity|ADP-dependent propionyl coenzyme A hydrolase activity|ADP-dependent short-chain acyl-CoA hydrolase activity http://purl.obolibrary.org/obo/GO_0047379 CHEBI:142057 biolink:ChemicalSubstance 3-hydroxy-L-aspartic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_142057 GO:0047378 biolink:MolecularActivity acetylalkylglycerol acetylhydrolase activity Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+). EC:3.1.1.71|RHEA:11552|KEGG_REACTION:R04043|MetaCyc:3.1.1.71-RXN go-plus.json 2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity|alkylacetylglycerol acetylhydrolase activity http://purl.obolibrary.org/obo/GO_0047378 GO:0047377 biolink:MolecularActivity 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+). EC:3.1.1.66|KEGG_REACTION:R04525|RHEA:16313|MetaCyc:3.1.1.66-RXN go-plus.json 3,4-diacetoxybutinylbithiophene:4-acetate esterase activity|5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity|diacetoxybutynylbithiophene acetate esterase activity http://purl.obolibrary.org/obo/GO_0047377 GO:0047376 biolink:MolecularActivity all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate. Reactome:R-HSA-2404140|RHEA:13933|Reactome:R-HSA-2429643|KEGG_REACTION:R02368|MetaCyc:3.1.1.64-RXN go-plus.json all-trans-retinyl-palmitate acylhydrolase activity|retinyl-palmitate palmitohydrolase activity|all-trans-retinyl-palmitate hydrolase activity http://purl.obolibrary.org/obo/GO_0047376 CHEBI:142054 biolink:ChemicalSubstance 3-hydroxyaspartic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_142054 CL:0002421 biolink:Cell nucleated reticulocyte A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. go-plus.json http://purl.obolibrary.org/obo/CL_0002421 CL:0002420 biolink:Cell immature T cell A T cell that has not completed T cell selection. go-plus.json immature T-cell http://purl.obolibrary.org/obo/CL_0002420 CL:0002423 biolink:Cell DN2a thymocyte A DN2 thymocyte that is Kit-hi. go-plus.json http://purl.obolibrary.org/obo/CL_0002423 CL:0002422 biolink:Cell enucleated reticulocyte A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes. go-plus.json http://purl.obolibrary.org/obo/CL_0002422 CL:0002425 biolink:Cell early T lineage precursor A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive. go-plus.json ETP|preT.ETP.Th http://purl.obolibrary.org/obo/CL_0002425 CL:0002424 biolink:Cell DN2b thymocyte A DN2 thymocyte that is Kit-low. go-plus.json http://purl.obolibrary.org/obo/CL_0002424 GO:0072339 biolink:BiologicalProcess cellular lactam biosynthetic process The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. go-plus.json cellular lactam biosynthesis|cellular lactam anabolism|cellular lactam synthesis|cellular lactam formation http://purl.obolibrary.org/obo/GO_0072339 GO:0072338 biolink:BiologicalProcess cellular lactam metabolic process The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. go-plus.json cellular lactam metabolism http://purl.obolibrary.org/obo/GO_0072338 GO:0072337 biolink:BiologicalProcess modified amino acid transport The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json amino acid derivative transport http://purl.obolibrary.org/obo/GO_0072337 GO:0072336 biolink:BiologicalProcess negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json negative regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0072336 GO:0072335 biolink:BiologicalProcess regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0072335 GO:0072334 biolink:BiologicalProcess UDP-galactose transmembrane transport The process in which UDP-galactose is transported across a membrane. go-plus.json UDP-galactose transport|UDP-galactose membrane transport http://purl.obolibrary.org/obo/GO_0072334 GO:0072333 biolink:BiologicalProcess obsolete anoikis by p53 class mediator OBSOLETE. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, that results in the induction of anoikis. go-plus.json anoikis by p53 class mediator|anoikis by signal transduction by p53 class mediator|signal transduction by p53 class mediator resulting in induction of anoikis http://purl.obolibrary.org/obo/GO_0072333 GO:0072332 biolink:BiologicalProcess intrinsic apoptotic signaling pathway by p53 class mediator A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered. go-plus.json intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|signal transduction by p53 class mediator resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_0072332 GO:0047386 biolink:MolecularActivity fructose-2,6-bisphosphate 6-phosphatase activity Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate. MetaCyc:3.1.3.54-RXN|EC:3.1.3.54|KEGG_REACTION:R02730|RHEA:13333 go-plus.json fructose-2,6-bisphosphate 6-phosphohydrolase activity|beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|fructose 2,6-bisphosphate-6-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047386 GO:0072320 biolink:MolecularActivity volume-sensitive chloride channel activity Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell. go-plus.json swell-activated chloride channel http://purl.obolibrary.org/obo/GO_0072320 GO:0047385 biolink:MolecularActivity [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]. MetaCyc:3.1.3.52-RXN|EC:3.1.3.52 go-plus.json branched-chain alpha-keto acid dehydrogenase phosphatase|branched-chain oxo-acid dehydrogenase phosphatase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity|branched-chain 2-keto acid dehydrogenase phosphatase activity http://purl.obolibrary.org/obo/GO_0047385 GO:0047384 biolink:MolecularActivity [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)]. MetaCyc:3.1.3.47-RXN|EC:3.1.3.47 go-plus.json hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity|hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity|reductase phosphatase activity http://purl.obolibrary.org/obo/GO_0047384 GO:0047383 biolink:MolecularActivity guanidinodeoxy-scyllo-inositol-4-phosphatase activity Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate. MetaCyc:3.1.3.40-RXN|EC:3.1.3.40|RHEA:15777|KEGG_REACTION:R03496 go-plus.json 1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity|1-guanidino-scyllo-inositol 4-phosphatase activity|1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047383 GO:0047382 biolink:MolecularActivity methylphosphothioglycerate phosphatase activity Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate. MetaCyc:3.1.3.14-RXN|RHEA:16081|EC:3.1.3.14|KEGG_REACTION:R04317 go-plus.json S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity|methylthiophosphoglycerate phosphatase activity http://purl.obolibrary.org/obo/GO_0047382 GO:0047381 biolink:MolecularActivity dodecanoyl-[acyl-carrier-protein] hydrolase activity Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein]. MetaCyc:3.1.2.21-RXN|RHEA:30119|EC:3.1.2.21 go-plus.json dodecanoyl-ACP hydrolase activity|lauryl-acyl-carrier-protein hydrolase activity|dodecyl-acyl-carrier protein hydrolase|dodecyl-[acyl-carrier protein] hydrolase activity|dodecanoyl-acyl-carrier-protein hydrolase activity|lauryl-[acyl-carrier protein] hydrolase activity|lauroyl-[acyl-carrier-protein] hydrolase activity|lauryl-acyl-carrier protein hydrolase activity|dodecanoyl-[acyl-carrier protein] hydrolase activity|lauroyl-ACP hydrolase activity http://purl.obolibrary.org/obo/GO_0047381 GO:0047380 biolink:MolecularActivity ADP-dependent medium-chain-acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP. EC:3.1.2.19|MetaCyc:3.1.2.19-RXN go-plus.json ADP-dependent medium-chain hydrolase activity|ADP-dependent-medium-chain-acyl-CoA hydrolase activity|ADP-dependent medium-chain acyl-CoA hydrolase activity|ADP-dependent myristoyl-CoA thioesterase activity|ADP-dependent medium-chain acyl-thioester hydrolase activity|ADP-dependent medium-chain acyl coenzyme A hydrolase activity http://purl.obolibrary.org/obo/GO_0047380 CL:0002437 biolink:Cell mature CD8 single-positive thymocyte A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. go-plus.json T.8SP24-.Th http://purl.obolibrary.org/obo/CL_0002437 GO:0047389 biolink:MolecularActivity glycerophosphocholine phosphodiesterase activity Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline. EC:3.1.4.2|RHEA:16061|Reactome:R-HSA-6814132|MetaCyc:3.1.4.2-RXN go-plus.json glycerophosphohydrolase activity|glycerophosphinicocholine diesterase activity|sn-glycero-3-phosphorylcholine diesterase activity|sn-glycero-3-phosphocholine glycerophosphohydrolase activity|glycerolphosphorylcholine phosphodiesterase activity|glycerylphosphorylcholinediesterase activity http://purl.obolibrary.org/obo/GO_0047389 GO:0047388 biolink:MolecularActivity [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)]. KEGG_REACTION:R03474|EC:2.7.7.89|MetaCyc:3.1.4.15-RXN|RHEA:43716 go-plus.json adenylyl-glutamate-ammonia ligase hydrolase activity|adenylyl(glutamine synthetase) hydrolase activity|adenylyl-glutamine-synthetasehydrolase activity|adenylyl-[glutamate-ammonia ligase] hydrolase activity|adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity http://purl.obolibrary.org/obo/GO_0047388 GO:0047387 biolink:MolecularActivity serine-ethanolaminephosphate phosphodiesterase activity Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine. RHEA:17113|MetaCyc:3.1.4.13-RXN|KEGG_REACTION:R02817|EC:3.1.4.13 go-plus.json SEP diesterase activity|serine-phosphoethanolamine ethanolaminephosphohydrolase activity|serine ethanolamine phosphodiester phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0047387 CL:0002430 biolink:Cell CD4-intermediate, CD8-positive double-positive thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. go-plus.json T.4int8+.Th http://purl.obolibrary.org/obo/CL_0002430 CL:0002432 biolink:Cell CD24-positive, CD4 single-positive thymocyte A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. go-plus.json T.4SP24int.Th|CD24-positive, CD4 single-positive semimature thymocyte http://purl.obolibrary.org/obo/CL_0002432 CL:0002431 biolink:Cell CD4-positive, CD8-intermediate double-positive thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor. go-plus.json T.4int8+.th http://purl.obolibrary.org/obo/CL_0002431 CL:0002434 biolink:Cell CD24-positive, CD8 single-positive thymocyte A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. go-plus.json T.8SP24int.Th|CD24-positive, CD8 single-positive semimature thymocyte http://purl.obolibrary.org/obo/CL_0002434 SO:0001914 biolink:SequenceFeature rDNA_replication_fork_barrier A DNA motif that is found in eukaryotic rDNA repeats, and is a site of replication fork pausing. go-plus.json RTS1 element|DNA spacer replication fork barrier|RTS1 barrier|RFB|rDNA replication fork barrier http://purl.obolibrary.org/obo/SO_0001914 CL:0002433 biolink:Cell CD69-positive, CD4-positive single-positive thymocyte A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. go-plus.json intermediate CD4-single-positive|T.4SP69+.Th http://purl.obolibrary.org/obo/CL_0002433 CL:0002436 biolink:Cell mature CD4 single-positive thymocyte A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. go-plus.json T.4SP24-.Th http://purl.obolibrary.org/obo/CL_0002436 CL:0002435 biolink:Cell CD69-positive, CD8-positive single-positive thymocyte A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. go-plus.json intermediate CD8-single-positive|T.8SP69+.Th http://purl.obolibrary.org/obo/CL_0002435 GO:0072329 biolink:BiologicalProcess monocarboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. go-plus.json http://purl.obolibrary.org/obo/GO_0072329 GO:0072328 biolink:MolecularActivity alkene binding Binding to an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. go-plus.json http://purl.obolibrary.org/obo/GO_0072328 GO:0072327 biolink:BiologicalProcess vulval cell fate specification The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes. go-plus.json http://purl.obolibrary.org/obo/GO_0072327 GO:0072326 biolink:BiologicalProcess vulval cell fate determination The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes. go-plus.json http://purl.obolibrary.org/obo/GO_0072326 GO:0072325 biolink:BiologicalProcess vulval cell fate commitment The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes. go-plus.json http://purl.obolibrary.org/obo/GO_0072325 GO:0072324 biolink:CellularComponent ascus epiplasm Ascus cytoplasm that is not packaged into ascospores. go-plus.json http://purl.obolibrary.org/obo/GO_0072324 GO:0072323 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072323 GO:0072322 biolink:BiologicalProcess protein transport across periplasmic space The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall. go-plus.json chaperone-mediated protein transport across periplasmic space http://purl.obolibrary.org/obo/GO_0072322 GO:0072321 biolink:BiologicalProcess obsolete chaperone-mediated protein transport OBSOLETE. The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0072321 GO:0047397 biolink:MolecularActivity dolichylphosphate-glucose phosphodiesterase activity Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose. EC:3.1.4.48|RHEA:13857|MetaCyc:3.1.4.48-RXN go-plus.json Dol-P-Glc phosphodiesterase activity|dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity|dolichol phosphoglucose phosphodiesterase activity|dolichyl-phosphate-glucose phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0047397 GO:0072353 biolink:BiologicalProcess cellular age-dependent response to reactive oxygen species Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. go-plus.json http://purl.obolibrary.org/obo/GO_0072353 GO:0047396 biolink:MolecularActivity glycosylphosphatidylinositol diacylglycerol-lyase activity Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate. EC:4.6.1.14|RHEA:14333|MetaCyc:3.1.4.47-RXN go-plus.json 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]|GPI-PLC activity|glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity|(glycosyl)phosphatidylinositol-specific phospholipase C activity|GPI-specific phospholipase C activity|VSG-lipase activity|6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity|variant-surface-glycoprotein phospholipase C activity|glycosylphosphatidylinositol-specific phospholipase C activity|glycosylphosphatidylinositol-phospholipase C activity http://purl.obolibrary.org/obo/GO_0047396 GO:0072352 biolink:BiologicalProcess tricarboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups. go-plus.json tricarboxylic acid catabolism|tricarboxylate catabolic process|tricarboxylic acid degradation|tricarboxylate catabolism|tricarboxylic acid breakdown http://purl.obolibrary.org/obo/GO_0072352 GO:0047395 biolink:MolecularActivity glycerophosphoinositol glycerophosphodiesterase activity Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+). Reactome:R-HSA-6813740|EC:3.1.4.44|RHEA:16501|KEGG_REACTION:R01193|MetaCyc:3.1.4.44-RXN go-plus.json sn-glycero(3)phosphoinositol glycerophosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity|sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047395 GO:0072351 biolink:BiologicalProcess tricarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups. go-plus.json tricarboxylic acid synthesis|tricarboxylic acid formation|tricarboxylic acid biosynthesis|tricarboxylate biosynthetic process|tricarboxylate biosynthesis|tricarboxylic acid anabolism http://purl.obolibrary.org/obo/GO_0072351 GO:0072350 biolink:BiologicalProcess tricarboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-). go-plus.json tricarboxylic acid metabolism http://purl.obolibrary.org/obo/GO_0072350 GO:0047394 biolink:MolecularActivity glycerophosphoinositol inositolphosphodiesterase activity Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol. EC:3.1.4.43|RHEA:14033|MetaCyc:3.1.4.43-RXN go-plus.json 1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity|D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity|1,2-cyclic-inositol-phosphate phosphodiesterase activity|D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity|inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047394 GO:0047393 biolink:MolecularActivity glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+). KEGG_REACTION:R02648|EC:3.1.4.42|RHEA:16493|MetaCyc:3.1.4.42-RXN go-plus.json rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity|rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047393 GO:0047392 biolink:MolecularActivity CMP-N-acylneuraminate phosphodiesterase activity Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP. EC:3.1.4.40|RHEA:20185|MetaCyc:3.1.4.40-RXN go-plus.json CMP-sialate hydrolase activity|cytidine monophosphate-N-acetylneuraminic acid hydrolase activity|cytidine monophosphosialate hydrolase activity|CMP-N-acylneuraminate N-acylneuraminohydrolase activity|cytidine monophosphosialic hydrolase activity|CMP-sialic acid hydrolase activity|CMP-N-acylneuraminic acid hydrolase activity|CMP-N-acetylneuraminate hydrolase activity http://purl.obolibrary.org/obo/GO_0047392 GO:0047391 biolink:MolecularActivity alkylglycerophosphoethanolamine phosphodiesterase activity Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate. RHEA:15965|MetaCyc:3.1.4.39-RXN|EC:3.1.4.39 go-plus.json lysophospholipase D activity|1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity http://purl.obolibrary.org/obo/GO_0047391 GO:0047390 biolink:MolecularActivity glycerophosphocholine cholinephosphodiesterase activity Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+). RHEA:19545|KEGG_REACTION:R02591|MetaCyc:3.1.4.38-RXN|Reactome:R-HSA-6814797|EC:3.1.4.38 go-plus.json sn-glycero-3-phosphocholine cholinephosphohydrolase activity|L-3-glycerylphosphinicocholine cholinephosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047390 CL:0002405 biolink:Cell gamma-delta thymocyte A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative). go-plus.json gammadelta thymocyte|gd thymocyte http://purl.obolibrary.org/obo/CL_0002405 CL:0002404 biolink:Cell fetal thymocyte A thymocyte found in the fetal thymus. go-plus.json http://purl.obolibrary.org/obo/CL_0002404 GO:0047399 biolink:MolecularActivity glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate. EC:3.1.4.51|RHEA:18045|MetaCyc:3.1.4.51-RXN go-plus.json alpha-glucose-1-phosphate phosphodiesterase activity|6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047399 GO:0047398 biolink:MolecularActivity dolichylphosphate-mannose phosphodiesterase activity Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose. EC:3.1.4.49|RHEA:12989|MetaCyc:3.1.4.49-RXN go-plus.json mannosylphosphodolichol phosphodiesterase activity|dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity http://purl.obolibrary.org/obo/GO_0047398 CL:0002401 biolink:Cell mature dendritic epithelial T cell precursor A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. go-plus.json mature DEC precursor|mature DETC precursor http://purl.obolibrary.org/obo/CL_0002401 CL:0002400 biolink:Cell Fraction B/C precursor B cell A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002400 CL:0002402 biolink:Cell Peyer's patch B cell A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative. go-plus.json Peyers patch B cell http://purl.obolibrary.org/obo/CL_0002402 GO:0072359 biolink:BiologicalProcess circulatory system development The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. go-plus.json cardiovascular system development http://purl.obolibrary.org/obo/GO_0072359 GO:0072358 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072358 GO:0072357 biolink:CellularComponent PTW/PP1 phosphatase complex A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0072357 GO:0072356 biolink:BiologicalProcess chromosome passenger complex localization to kinetochore A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. go-plus.json CPC localization to kinetochore|chromosome passenger complex localisation to kinetochore|chromosomal passenger complex localization to kinetochore|CPC complex localization to kinetochore http://purl.obolibrary.org/obo/GO_0072356 GO:0072355 biolink:BiologicalProcess histone H3-T3 phosphorylation The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0072355 GO:0072354 biolink:MolecularActivity histone kinase activity (H3-T3 specific) Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3. go-plus.json histone-threonine kinase activity (H3-T3 specific)|histone threonine kinase activity (H3-T3 specific) http://purl.obolibrary.org/obo/GO_0072354 GO:0072342 biolink:BiologicalProcess response to anion stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0072342 GO:0106100 biolink:MolecularActivity beta-pinacene synthase activity Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene. go-plus.json http://purl.obolibrary.org/obo/GO_0106100 GO:0072341 biolink:MolecularActivity modified amino acid binding Binding to a modified amino acid. go-plus.json amino acid derivative binding http://purl.obolibrary.org/obo/GO_0072341 GO:0072340 biolink:BiologicalProcess cellular lactam catabolic process The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. go-plus.json cellular lactam degradation|cellular lactam breakdown|cellular lactam catabolism http://purl.obolibrary.org/obo/GO_0072340 GO:0106104 biolink:BiologicalProcess regulation of glutamate receptor clustering Any process that modulates the frequency, rate or extent of glutamate receptor clustering. go-plus.json http://purl.obolibrary.org/obo/GO_0106104 GO:0106103 biolink:CellularComponent COPII vesicles tethering complex A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae. go-plus.json GRASP65-GM130 complex|Bug1-Grh1 complex http://purl.obolibrary.org/obo/GO_0106103 GO:0106101 biolink:BiologicalProcess ER-dependent peroxisome localization A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0106101 GO:0106108 biolink:BiologicalProcess negative regulation of (R)-mevalonic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106108 GO:0106107 biolink:BiologicalProcess regulation of (R)-mevalonic acid biosynthetic process Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106107 GO:0106106 biolink:BiologicalProcess cold-induced thermogenesis The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature. go-plus.json CIT http://purl.obolibrary.org/obo/GO_0106106 CL:0002418 biolink:Cell hemangioblast A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells. go-plus.json http://purl.obolibrary.org/obo/CL_0002418 GO:0106105 biolink:MolecularActivity Ala-tRNA(Thr) hydrolase activity Catalysis of the hydrolysis of misacylated ala-tRNA(thr). go-plus.json L-alanyl-tRNA(Thr) deacylase http://purl.obolibrary.org/obo/GO_0106105 CL:0002417 biolink:Cell primitive erythroid lineage cell An immature or mature cell of the first erythroid lineage to arise during embryonic development. go-plus.json http://purl.obolibrary.org/obo/CL_0002417 CL:0002419 biolink:Cell mature T cell A T cell that expresses a T cell receptor complex and has completed T cell selection. go-plus.json mature T-cell|CD3epsilon T cell|CD3e-positive T cell http://purl.obolibrary.org/obo/CL_0002419 GO:0106109 biolink:BiologicalProcess positive regulation of (R)-mevalonic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106109 CL:0002410 biolink:Cell pancreatic stellate cell A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast. go-plus.json PaSC|pancreas stellate cell http://purl.obolibrary.org/obo/CL_0002410 GO:0072349 biolink:MolecularActivity modified amino acid transmembrane transporter activity Enables the transfer of modified amino acids from one side of a membrane to the other. go-plus.json modified amino acid transporter activity|amino acid derivative transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0072349 GO:0072348 biolink:BiologicalProcess sulfur compound transport The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json sulfur-containing compound transport http://purl.obolibrary.org/obo/GO_0072348 GO:0072347 biolink:BiologicalProcess response to anesthetic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation. go-plus.json response to anaesthetic http://purl.obolibrary.org/obo/GO_0072347 GO:0072346 biolink:MolecularActivity cADPR-sensitive calcium-release channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0072346 GO:0072345 biolink:MolecularActivity NAADP-sensitive calcium-release channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts. Reactome:R-HSA-2685505 go-plus.json http://purl.obolibrary.org/obo/GO_0072345 GO:0072344 biolink:BiologicalProcess rescue of stalled ribosome A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex. go-plus.json http://purl.obolibrary.org/obo/GO_0072344 GO:0072343 biolink:BiologicalProcess pancreatic stellate cell proliferation The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus. go-plus.json http://purl.obolibrary.org/obo/GO_0072343 GO:0072375 biolink:BiologicalProcess medium-term memory The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster). go-plus.json MTM|middle-term memory http://purl.obolibrary.org/obo/GO_0072375 GO:0072374 biolink:MolecularActivity carotene epsilon hydroxylase activity Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene. go-plus.json http://purl.obolibrary.org/obo/GO_0072374 GO:0072373 biolink:MolecularActivity alpha-carotene epsilon hydroxylase activity Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0072373 GO:0072372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072372 GO:0072371 biolink:MolecularActivity histone kinase activity (H2A-S121 specific) Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A. go-plus.json histone serine kinase activity (H2A-S121 specific)|histone-serine kinase activity (H2A-S121 specific) http://purl.obolibrary.org/obo/GO_0072371 GO:0072370 biolink:BiologicalProcess histone H2A-S121 phosphorylation The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone. go-plus.json histone H2A phosphorylation at S121|histone H2AS121 phosphorylation http://purl.obolibrary.org/obo/GO_0072370 CHEBI:132683 biolink:ChemicalSubstance (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132683 CHEBI:132685 biolink:ChemicalSubstance phosphatidylglycerol 36:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132685 CHEBI:132684 biolink:ChemicalSubstance phosphatidylglycerol 13:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132684 CHEBI:132687 biolink:ChemicalSubstance phosphatidylglycerol 38:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132687 CHEBI:132686 biolink:ChemicalSubstance phosphatidylglycerol 37:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_132686 GO:0072379 biolink:CellularComponent ER membrane insertion complex A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast. go-plus.json endoplasmic reticulum membrane insertion complex http://purl.obolibrary.org/obo/GO_0072379 CHEBI:50299 biolink:ChemicalSubstance canonical ribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50299 GO:0072378 biolink:BiologicalProcess blood coagulation, fibrin clot formation A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events. go-plus.json http://purl.obolibrary.org/obo/GO_0072378 CHEBI:50298 biolink:ChemicalSubstance canonical deoxyribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50298 CHEBI:50297 biolink:ChemicalSubstance canonical nucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50297 GO:0072377 biolink:BiologicalProcess blood coagulation, common pathway A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex. go-plus.json http://purl.obolibrary.org/obo/GO_0072377 CHEBI:132681 biolink:ChemicalSubstance (12S)-hydroperoxy-(14S,15R)-epoxy-(5Z,8Z,10E)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132681 GO:0072376 biolink:BiologicalProcess protein activation cascade A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events. go-plus.json protein activitory cascade|protein activation pathway http://purl.obolibrary.org/obo/GO_0072376 GO:0072364 biolink:BiologicalProcess obsolete regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of cellular ketone metabolic process by regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072364 GO:0072363 biolink:BiologicalProcess obsolete regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072363 GO:0072362 biolink:BiologicalProcess obsolete regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072362 GO:0072361 biolink:BiologicalProcess obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0072361 GO:0072360 biolink:BiologicalProcess vascular cord development The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0072360 CHEBI:49299 biolink:ChemicalSubstance D-fructofuranose 1,6-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49299 chebi_ph7_3 CHEBI:49298 biolink:ChemicalSubstance N-formyl-L-methionyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_49298 chebi_ph7_3 CHEBI:50284 biolink:ChemicalSubstance lavandulyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50284 CHEBI:50281 biolink:ChemicalSubstance lavandulol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50281 chebi_ph7_3 GO:0072369 biolink:BiologicalProcess obsolete regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072369 GO:0072368 biolink:BiologicalProcess obsolete regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072368 GO:0072367 biolink:BiologicalProcess obsolete regulation of lipid transport by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of lipid transport by regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072367 GO:0072366 biolink:BiologicalProcess obsolete regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by positive regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072366 GO:0072365 biolink:BiologicalProcess obsolete regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by negative regulation of transcription from an RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0072365 GO:0072397 biolink:BiologicalProcess obsolete detection of stimulus involved in cytokinesis checkpoint OBSOLETE. The series of events in which information about the formation and integrity of cytokinetic structures, such as the contractile ring, is received and converted into a molecular signal, contributing to a cytokinesis checkpoint. go-plus.json cytokinesis checkpoint sensor mechanism|septin checkpoint sensor process|cytokinesis checkpoint sensor process|detection of stimulus involved in septin checkpoint|sensing involved in septin checkpoint|sensing involved in cytokinesis checkpoint|septin checkpoint sensor mechanism http://purl.obolibrary.org/obo/GO_0072397 GO:0072396 biolink:BiologicalProcess response to cell cycle checkpoint signaling A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling. go-plus.json G1/S transition checkpoint effector process|response to G2/M transition checkpoint signaling|response to signal involved in G1/S transition checkpoint|response to signal involved in cell cycle checkpoint|response to signal involved in G2/M transition checkpoint|cell cycle checkpoint effector process|G2/M transition checkpoint effector process|response to G1/S transition checkpoint signaling http://purl.obolibrary.org/obo/GO_0072396 CHEBI:50279 biolink:ChemicalSubstance (1S,2S,3S)-prephytoene diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50279 GO:0072395 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0072395 GO:0072394 biolink:BiologicalProcess obsolete detection of stimulus involved in cell cycle checkpoint OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a cell cycle checkpoint. go-plus.json detection of stimulus involved in G1/S transition checkpoint|detection of stimulus involved in G2/M transition checkpoint|sensing involved in G1/S transition checkpoint|G2/M transition checkpoint sensor mechanism|sensing involved in G2/M transition checkpoint|cell cycle checkpoint sensor mechanism|G1/S transition checkpoint sensor mechanism|G2/M transition checkpoint sensor process|sensing involved in cell cycle checkpoint|cell cycle checkpoint sensor process|G1/S transition checkpoint sensor process http://purl.obolibrary.org/obo/GO_0072394 GO:0072393 biolink:BiologicalProcess microtubule anchoring at microtubule organizing center Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center. go-plus.json microtubule anchoring at MTOC|microtubule anchoring at microtubule organising centre http://purl.obolibrary.org/obo/GO_0072393 GO:0072392 biolink:BiologicalProcess phenol catabolic process The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0072392 GO:0072391 biolink:BiologicalProcess phenol biosynthetic process The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0072391 GO:0072390 biolink:BiologicalProcess phenol metabolic process The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0072390 CHEBI:49284 biolink:ChemicalSubstance cis-hex-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49284 CHEBI:49283 biolink:ChemicalSubstance 3-hexenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49283 CHEBI:49285 biolink:ChemicalSubstance trans-hex-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49285 CHEBI:49289 biolink:ChemicalSubstance humulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49289 CHEBI:49290 biolink:ChemicalSubstance gamma-humulene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49290 chebi_ph7_3 CHEBI:50273 biolink:ChemicalSubstance (R,R)-chrysanthemyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50273 CHEBI:50272 biolink:ChemicalSubstance chrysanthemyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50272 CHEBI:50271 biolink:ChemicalSubstance (1R,2S,5S,6S)-2-(3-carboxypropanoyl)-5-[(1-carboxyvinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50271 CHEBI:50277 biolink:ChemicalSubstance farnesyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50277 CHEBI:50276 biolink:ChemicalSubstance EC 5.99.1.2 (DNA topoisomerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50276 GO:0072399 biolink:BiologicalProcess response to cytokinesis checkpoint signaling A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling. go-plus.json cytokinesis checkpoint effector process|response to signal involved in cytokinesis checkpoint http://purl.obolibrary.org/obo/GO_0072399 GO:0072398 biolink:BiologicalProcess signal transduction involved in cytokinesis checkpoint A signal transduction process that contributes to a cytokinesis checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_0072398 CHEBI:50274 biolink:ChemicalSubstance secoiridoid glycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_50274 GO:0072386 biolink:BiologicalProcess plus-end-directed organelle transport along microtubule The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. go-plus.json microtubule plus-end-directed organelle localization|microtubule plus-end-directed organelle distribution http://purl.obolibrary.org/obo/GO_0072386 GO:0072385 biolink:BiologicalProcess minus-end-directed organelle transport along microtubule The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. go-plus.json microtubule minus-end-directed organelle distribution|microtubule minus-end-directed organelle localization http://purl.obolibrary.org/obo/GO_0072385 CHEBI:50269 biolink:ChemicalSubstance EC 1.1.1.1 (alcohol dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50269 GO:0072384 biolink:BiologicalProcess organelle transport along microtubule The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. go-plus.json microtubule-based organelle localization http://purl.obolibrary.org/obo/GO_0072384 CHEBI:50268 biolink:ChemicalSubstance GABA modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50268 GO:0072383 biolink:BiologicalProcess plus-end-directed vesicle transport along microtubule The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. go-plus.json microtubule plus-end-directed vesicle localization|microtubule plus-end-directed vesicle distribution http://purl.obolibrary.org/obo/GO_0072383 CHEBI:50267 biolink:ChemicalSubstance protective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50267 GO:0072382 biolink:BiologicalProcess minus-end-directed vesicle transport along microtubule The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. go-plus.json microtubule minus-end-directed vesicle distribution|microtubule minus-end-directed vesicle localization http://purl.obolibrary.org/obo/GO_0072382 GO:0072381 biolink:BiologicalProcess positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. go-plus.json positive regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|positive regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0072381 GO:0072380 biolink:CellularComponent TRC complex A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane. go-plus.json TMD recognition complex|GET4-GET5 transmembrane domain recognition complex http://purl.obolibrary.org/obo/GO_0072380 CHEBI:49273 biolink:ChemicalSubstance cholenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49273 CHEBI:49272 biolink:ChemicalSubstance selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49272 CHEBI:49275 biolink:ChemicalSubstance chol-4-en-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49275 CHEBI:49274 biolink:ChemicalSubstance (-)-beta-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49274 chebi_ph7_3 CHEBI:49277 biolink:ChemicalSubstance chola-4,6-dien-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49277 CHEBI:49276 biolink:ChemicalSubstance beta-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49276 CHEBI:49279 biolink:ChemicalSubstance (+)-delta-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49279 chebi_ph7_3 CHEBI:49278 biolink:ChemicalSubstance delta-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49278 chebi_ph7_3 CHEBI:132671 biolink:ChemicalSubstance (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-icosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132671 CHEBI:49280 biolink:ChemicalSubstance (-)-delta-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_49280 chebi_ph7_3 CHEBI:132678 biolink:ChemicalSubstance 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132678 CHEBI:50262 biolink:ChemicalSubstance 2-(3-methylthiopropyl)malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50262 CHEBI:50261 biolink:ChemicalSubstance 2-(2-methylthioethyl)malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50261 CHEBI:50260 biolink:ChemicalSubstance 5-methylthio-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50260 CHEBI:50266 biolink:ChemicalSubstance prodrug go-plus.json http://purl.obolibrary.org/obo/CHEBI_50266 GO:0072389 biolink:BiologicalProcess flavin adenine dinucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json flavin adenine dinucleotide catabolism|FAD or FADH2 catabolic process|flavin adenine dinucleotide degradation|flavin adenine dinucleotide breakdown http://purl.obolibrary.org/obo/GO_0072389 GO:0072388 biolink:BiologicalProcess flavin adenine dinucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json flavin adenine dinucleotide biosynthesis|FAD or FADH2 biosynthetic process|flavin adenine dinucleotide anabolism|flavin adenine dinucleotide synthesis|flavin adenine dinucleotide formation http://purl.obolibrary.org/obo/GO_0072388 GO:0072387 biolink:BiologicalProcess flavin adenine dinucleotide metabolic process The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json flavin adenine dinucleotide metabolism|flavin-adenine dinucleotide metabolic process|FAD or FADH2 metabolic process http://purl.obolibrary.org/obo/GO_0072387 CHEBI:50263 biolink:ChemicalSubstance 2-hydroxydicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50263 GO:0106155 biolink:MolecularActivity peptidyl-lysine 3-dioxygenase activity Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2. RHEA:57152|EC:1.14.11.63 go-plus.json http://purl.obolibrary.org/obo/GO_0106155 GO:0106154 biolink:BiologicalProcess perithecium formation The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck. go-plus.json http://purl.obolibrary.org/obo/GO_0106154 GO:0106153 biolink:MolecularActivity phosphorylated histone binding Binding to a histone in which a residue has been modified by phosphorylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0106153 CHEBI:74228 biolink:ChemicalSubstance 3-oxotriacontanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74228 chebi_ph7_3 GO:0106159 biolink:BiologicalProcess regulation of small RNA loading onto RISC Any process that modulates the frequency, rate or extent small RNA loading onto RISC. go-plus.json http://purl.obolibrary.org/obo/GO_0106159 GO:0106158 biolink:MolecularActivity glycero-3-phosphocholine acyltransferase activity Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine. RHEA:58476 go-plus.json GPACT activity|glycero-3-phosphocholine acyltransferase activity|glycerophosphocholine O-acyltransferase activity http://purl.obolibrary.org/obo/GO_0106158 CHEBI:74229 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74229 chebi_ph7_3 GO:0106157 biolink:MolecularActivity peptidyl-arginine 3-dioxygenase activity Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate. RHEA:56744 go-plus.json L-arginine 3-hydroxylase activity http://purl.obolibrary.org/obo/GO_0106157 GO:0106156 biolink:MolecularActivity peptidyl-lysine 4-dioxygenase activity Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2. RHEA:57156 go-plus.json http://purl.obolibrary.org/obo/GO_0106156 UBERON:0036376 biolink:AnatomicalEntity wall of left ureter go-plus.json left ureteral wall http://purl.obolibrary.org/obo/UBERON_0036376 UBERON:0036375 biolink:AnatomicalEntity wall of right ureter go-plus.json right ureteral wall http://purl.obolibrary.org/obo/UBERON_0036375 CHEBI:15929 biolink:ChemicalSubstance (-)-methyl jasmonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15929 chebi_ph7_3 CHEBI:15926 biolink:ChemicalSubstance dolichyl diphosphooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15926 CHEBI:15925 biolink:ChemicalSubstance 2-dehydro-3-deoxy-6-phospho-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15925 CHEBI:15927 biolink:ChemicalSubstance N-ribosylnicotinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15927 chebi_ph7_3 CL:1000296 biolink:Cell epithelial cell of urethra An epithelial cell that is part of the urethra. go-plus.json http://purl.obolibrary.org/obo/CL_1000296 CHEBI:15920 biolink:ChemicalSubstance columbamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15920 chebi_ph7_3 CHEBI:74220 biolink:ChemicalSubstance C17 sphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74220 GO:0106162 biolink:MolecularActivity mRNA N-acetyltransferase activity Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H(+) + phosphate. RHEA:58480 go-plus.json http://purl.obolibrary.org/obo/GO_0106162 CHEBI:74222 biolink:ChemicalSubstance gamma-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_74222 GO:0106161 biolink:BiologicalProcess positive regulation of small RNA loading onto RISC Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC. go-plus.json http://purl.obolibrary.org/obo/GO_0106161 GO:0106160 biolink:BiologicalProcess negative regulation of small RNA loading onto RISC Any process that stops, prevents or reduces the frequency, rate or extent of small RNA loading onto RISC. go-plus.json http://purl.obolibrary.org/obo/GO_0106160 CHEBI:74224 biolink:ChemicalSubstance genistein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74224 chebi_ph7_3 CHEBI:74223 biolink:ChemicalSubstance pyrrolidin-2-ones go-plus.json http://purl.obolibrary.org/obo/CHEBI_74223 chebi_ph7_3 GO:0106166 biolink:MolecularActivity spindle pole body-nuclear membrane anchor activity The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body. go-plus.json spindle pole body nuclear membrane anchor activity|nuclear membrane-spindle pole body anchor activity http://purl.obolibrary.org/obo/GO_0106166 CHEBI:74237 biolink:ChemicalSubstance phosphatidylinositol 34:1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74237 chebi_ph7_3 GO:0106165 biolink:BiologicalProcess negative regulation of exonucleolytic catabolism of deadenylated mRNA Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay. go-plus.json http://purl.obolibrary.org/obo/GO_0106165 GO:0106164 biolink:BiologicalProcess positive regulation of exonucleolytic catabolism of deadenylated mRNA Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay. go-plus.json http://purl.obolibrary.org/obo/GO_0106164 GO:0106163 biolink:BiologicalProcess regulation of exonucleolytic catabolism of deadenylated mRNA Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay. go-plus.json http://purl.obolibrary.org/obo/GO_0106163 CHEBI:74238 biolink:ChemicalSubstance phosphatidylinositol 34:2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74238 chebi_ph7_3 GO:0106167 biolink:BiologicalProcess extracellular ATP signaling A series of molecular signals mediated by the detection of extracellular ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0106167 GO:0047306 biolink:MolecularActivity D-methionine-pyruvate transaminase activity Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine. RHEA:23836|EC:2.6.1.41|KEGG_REACTION:R03001|MetaCyc:2.6.1.41-RXN go-plus.json D-methionine aminotransferase activity|D-methionine-pyruvate aminotransferase activity|D-methionine transaminase activity|D-methionine--pyruvate aminotransferase activity|D-methionine:pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047306 CHEBI:15919 biolink:ChemicalSubstance N(6)-(1,2-dicarboxyethyl)-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_15919 GO:0047305 biolink:MolecularActivity (R)-3-amino-2-methylpropionate-pyruvate transaminase activity Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine. EC:2.6.1.40|KEGG_REACTION:R02050|RHEA:18393|MetaCyc:2.6.1.40-RXN|Reactome:R-HSA-909780 go-plus.json (R)-3-amino-2-methylpropionate transaminase activity|D-3-aminoisobutyrate--pyruvate aminotransferase activity|(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity|D-AIBAT activity|D-3-aminoisobutyrate-pyruvate transaminase activity|(R)-3-amino-2-methylpropanoate aminotransferase activity|(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity|D-3-aminoisobutyrate--pyruvate transaminase activity|beta-aminoisobutyrate-pyruvate aminotransferase activity|beta-aminoisobutyrate--pyruvate transaminase activity|(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity|(R)-3-amino-2-methylpropanoate transaminase activity|D-beta-aminoisobutyrate:pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047305 CHEBI:15918 biolink:ChemicalSubstance 2'-deoxycytosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15918 GO:0047304 biolink:MolecularActivity 2-aminoethylphosphonate-pyruvate transaminase activity Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde. EC:2.6.1.37|KEGG_REACTION:R04152|MetaCyc:2.6.1.37-RXN|RHEA:17021 go-plus.json (2-aminoethyl)phosphonate--pyruvate aminotransferase activity|(2-aminoethyl)phosphonate aminotransferase activity|2-aminoethylphosphonate-pyruvate aminotransferase activity|2-aminoethylphosphonate--pyruvate aminotransferase activity|(2-aminoethyl)phosphonate:pyruvate aminotransferase activity|(2-aminoethyl)phosphonic acid aminotransferase activity|(2-aminoethyl)phosphonate transaminase activity|2-aminoethylphosphonate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047304 GO:0047303 biolink:MolecularActivity glycine-oxaloacetate transaminase activity Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate. EC:2.6.1.35|KEGG_REACTION:R00373|RHEA:17141|MetaCyc:2.6.1.35-RXN go-plus.json glycine-oxalacetate aminotransferase activity|glycine:oxaloacetate aminotransferase activity|glycine-oxaloacetate aminotransferase activity|glycine--oxaloacetate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047303 GO:0047302 biolink:MolecularActivity UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose. KEGG_REACTION:R04529|EC:2.6.1.34|RHEA:31663|MetaCyc:2.6.1.34-RXN go-plus.json UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity|UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity|UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity|uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity http://purl.obolibrary.org/obo/GO_0047302 CHEBI:15915 biolink:ChemicalSubstance ADP-L-glycero-D-manno-heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15915 GO:0047301 biolink:MolecularActivity valine-3-methyl-2-oxovalerate transaminase activity Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine. RHEA:11468|EC:2.6.1.32|KEGG_REACTION:R02200|MetaCyc:2.6.1.32-RXN go-plus.json L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity|valine-3-methyl-2-oxovalerate aminotransferase activity|valine--isoleucine transaminase activity|valine--3-methyl-2-oxovalerate aminotransferase activity|valine--isoleucine aminotransferase activity|valine-2-keto-methylvalerate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047301 CHEBI:15914 biolink:ChemicalSubstance 2-amino-4-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15914 CHEBI:15917 biolink:ChemicalSubstance N-(D-glucopyranosyl)nicotinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15917 chebi_ph7_3 GO:0047300 biolink:MolecularActivity pyridoxamine-pyruvate transaminase activity Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal. KEGG_REACTION:R01712|RHEA:12841|EC:2.6.1.30|MetaCyc:2.6.1.30-RXN go-plus.json pyridoxamine-pyruvate aminotransferase activity|pyridoxamine:pyruvate aminotransferase activity|pyridoxamineu-pyruvic transaminase activity|pyridoxamine-pyruvic transaminase|pyridoxamine--pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047300 CHEBI:15916 biolink:ChemicalSubstance serine phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15916 CHEBI:15911 biolink:ChemicalSubstance desulfoglucotropeolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15911 chebi_ph7_3 CHEBI:15913 biolink:ChemicalSubstance (R)-2-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15913 GO:0047309 biolink:MolecularActivity dihydroxyphenylalanine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate. EC:2.6.1.49|KEGG_REACTION:R02077|MetaCyc:2.6.1.49-RXN|RHEA:15273 go-plus.json glutamate-DOPP transaminase (GDT)|dihydroxyphenylalanine aminotransferase activity|L-dopa transaminase activity|dopa transaminase activity|3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity|aspartate-DOPP transaminase (ADT)|phenylalanine-DOPP transaminase (PDT)|DOPA aminotransferase activity http://purl.obolibrary.org/obo/GO_0047309 GO:0047308 biolink:MolecularActivity alanine-oxomalonate transaminase activity Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate. RHEA:18809|EC:2.6.1.47|KEGG_REACTION:R02970|MetaCyc:2.6.1.47-RXN go-plus.json L-alanine:oxomalonate aminotransferase activity|L-alanine-ketomalonate transaminase activity|alanine-oxomalonate aminotransferase activity|alanine--oxomalonate aminotransferase activity|alanine-ketomalonate (mesoxalate) transaminase activity http://purl.obolibrary.org/obo/GO_0047308 GO:0047307 biolink:MolecularActivity diaminobutyrate-pyruvate transaminase activity Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde. EC:2.6.1.46|KEGG_REACTION:R02293|RHEA:12380|MetaCyc:2.6.1.46-RXN go-plus.json L-diaminobutyric acid transaminase activity|diaminobutyrate-pyruvate aminotransferase activity|diaminobutyrate--pyruvate aminotransferase activity|L-2,4-diaminobutanoate:pyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047307 CL:1000281 biolink:Cell smooth muscle cell of cecum A smooth muscle cell that is part of the cecum. go-plus.json smooth muscle fiber of cecum|non-striated muscle fiber of cecum http://purl.obolibrary.org/obo/CL_1000281 CL:1000280 biolink:Cell smooth muscle cell of colon A smooth muscle cell that is part of the colon. go-plus.json non-striated muscle fiber of colon http://purl.obolibrary.org/obo/CL_1000280 CHEBI:74231 biolink:ChemicalSubstance phosphatidylinositol 32:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74231 chebi_ph7_3 CHEBI:74230 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z,25Z)-3-oxooctacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74230 chebi_ph7_3 GO:0106173 biolink:CellularComponent COPII-coated vesicle lumen The volume enclosed by the membrane of a COPII-coated endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0106173 CHEBI:74233 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74233 chebi_ph7_3 GO:0106172 biolink:CellularComponent COPI-coated vesicle lumen The volume enclosed by the membrane of a COPI-coated endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0106172 CHEBI:74232 biolink:ChemicalSubstance phosphatidylinositol 34:0(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74232 chebi_ph7_3 SO:0001997 biolink:SequenceFeature subtelomere A heterochromatic region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes and it is transcribed. go-plus.json http://purl.obolibrary.org/obo/SO_0001997 GO:0106177 biolink:MolecularActivity cyclic-GMP-AMP hydrolase activity Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP. RHEA:58808 go-plus.json http://purl.obolibrary.org/obo/GO_0106177 CHEBI:74247 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74247 chebi_ph7_3 GO:0106176 biolink:CellularComponent clathrin-coated endocytic vesicle lumen The volume enclosed by the membrane of a clathrin-coated endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0106176 GO:0106175 biolink:CellularComponent phagolysosome vesicle membrane The lipid bylayer surrounding a phagolysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0106175 GO:0106174 biolink:CellularComponent phagolysosome vesicle lumen The volume enclosed by the membrane of a phagolysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0106174 CHEBI:74249 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74249 chebi_ph7_3 GO:0106179 biolink:MolecularActivity obsolete translocase activity acting on inorganic cations and their chelates OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates. EC:7.2.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106179 GO:0106178 biolink:MolecularActivity obsolete translocase activity OBSOLETE. Catalysis the movement of ions or molecules across membranes or their separation within membranes. EC:7.-.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106178 GO:0047317 biolink:MolecularActivity N6-acetyl-beta-lysine transaminase activity Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate. MetaCyc:2.6.1.65-RXN|RHEA:16889|EC:2.6.1.65 go-plus.json 6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity|N6-acetyl-beta-lysine aminotransferase activity|epsilon-acetyl-beta-lysine aminotransferase activity|N(6)-acetyl-beta-lysine aminotransferase activity http://purl.obolibrary.org/obo/GO_0047317 GO:0047316 biolink:MolecularActivity glutamine-phenylpyruvate transaminase activity Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine. RHEA:17593|MetaCyc:2.6.1.64-RXN|EC:2.6.1.64|KEGG_REACTION:R01375 go-plus.json glutamine-phenylpyruvate aminotransferase activity|glutamine transaminase K activity|glutamine--phenylpyruvate aminotransferase activity|L-glutamine:phenylpyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047316 GO:0047315 biolink:MolecularActivity kynurenine-glyoxylate transaminase activity Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine. MetaCyc:2.6.1.63-RXN|KEGG_REACTION:R01957|EC:2.6.1.63|RHEA:19249 go-plus.json kynurenine--glyoxylate aminotransferase activity|kynurenine-glyoxylate aminotransferase activity|L-kynurenine:glyoxylate aminotransferase (cyclizing) http://purl.obolibrary.org/obo/GO_0047315 GO:0047314 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047314 GO:0047313 biolink:MolecularActivity aromatic-amino-acid-glyoxylate transaminase activity Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid. MetaCyc:2.6.1.60-RXN|RHEA:10900|EC:2.6.1.60 go-plus.json aromatic-amino-acid-glyoxylate aminotransferase activity|aromatic-amino-acid--glyoxylate aminotransferase activity|aromatic-amino-acid:glyoxylate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047313 CHEBI:15948 biolink:ChemicalSubstance lycopene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15948 chebi_ph7_3 GO:0047312 biolink:MolecularActivity L-phenylalanine:pyruvate aminotransferase activity Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine. MetaCyc:2.6.1.58-RXN|EC:2.6.1.58|Reactome:R-HSA-893593|KEGG_REACTION:R00692|RHEA:13053 go-plus.json phenylalanine(histidine):pyruvate aminotransferase activity|L-histidine:pyruvate aminotransferase activity|L-phenylalanine(L-histidine):pyruvate aminotransferase activity|phenylalanine (histidine) aminotransferase activity|histidine:pyruvate aminotransferase activity|phenylalanine(histidine) aminotransferase activity|L-phenylalanine:pyruvate transaminase activity|histidine aminotransferase activity|phenylalanine(histidine) transaminase activity http://purl.obolibrary.org/obo/GO_0047312 CHEBI:15947 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15947 chebi_ph7_3 GO:0047311 biolink:MolecularActivity 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine. MetaCyc:2.6.1.56-RXN|EC:2.6.1.56|KEGG_REACTION:R03502|RHEA:15497 go-plus.json 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity|L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity|guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity|1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity http://purl.obolibrary.org/obo/GO_0047311 GO:0047310 biolink:MolecularActivity glutamine-scyllo-inositol transaminase activity Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate. MetaCyc:2.6.1.50-RXN|RHEA:22920|KEGG_REACTION:R02781|EC:2.6.1.50 go-plus.json glutamine-scyllo-inosose transaminase activity|glutamine--scyllo-inosose transaminase activity|glutamine-scyllo-inosose aminotransferase activity|glutamine scyllo-inosose aminotransferase activity|glutamine--scyllo-inosose aminotransferase activity|L-glutamine-scyllo-inosose transaminase activity|L-glutamine-keto-scyllo-inositol aminotransferase activity|L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity http://purl.obolibrary.org/obo/GO_0047310 CHEBI:15949 biolink:ChemicalSubstance diphthamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15949 CHEBI:15944 biolink:ChemicalSubstance 6-O-methylnorlaudanosoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_15944 CL:0002485 biolink:Cell retinal melanocyte A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium. go-plus.json http://purl.obolibrary.org/obo/CL_0002485 CHEBI:15943 biolink:ChemicalSubstance poly(glycerol phosphate) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_15943 CL:0002484 biolink:Cell epithelial melanocyte A melanocyte that produces pigment in the epithelium. go-plus.json http://purl.obolibrary.org/obo/CL_0002484 CHEBI:15946 biolink:ChemicalSubstance keto-D-fructose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15946 CHEBI:15945 biolink:ChemicalSubstance D-galactono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15945 chebi_ph7_3 CL:0002489 biolink:Cell double negative thymocyte A thymocyte that lacks expression of CD4 and CD8. go-plus.json double negative T cell|CD4-CD8- T cell http://purl.obolibrary.org/obo/CL_0002489 CHEBI:15940 biolink:ChemicalSubstance nicotinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15940 CL:0002488 biolink:Cell trophoblast giant cell A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta. go-plus.json giant trophoblast cell http://purl.obolibrary.org/obo/CL_0002488 GO:0047319 biolink:MolecularActivity aspartate-phenylpyruvate transaminase activity Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate. RHEA:14097|MetaCyc:2.6.1.70-RXN|KEGG_REACTION:R00695|EC:2.6.1.70 go-plus.json aspartate-phenylpyruvate aminotransferase activity|L-aspartate:phenylpyruvate aminotransferase activity|aspartate--phenylpyruvate aminotransferase activity http://purl.obolibrary.org/obo/GO_0047319 CHEBI:15942 biolink:ChemicalSubstance 2-aminobenzenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15942 chebi_ph7_3 GO:0047318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047318 CHEBI:15941 biolink:ChemicalSubstance 2,3-dihydroxy-2,3-dihydrobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15941 CHEBI:74240 biolink:ChemicalSubstance phosphatidylinositol 38:4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74240 chebi_ph7_3 GO:0106180 biolink:MolecularActivity obsolete translocase activty of hydrons OBSOLETE. Catalysis of the translocation of hydrons (hydron being the general name for H+ in its natural abundance). EC:7.1.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106180 GO:0106184 biolink:MolecularActivity obsolete translocation activity acting on other compounds OBSOLETE. Catalysis of the translocation of other compounds not included in EC:7.1 through EC:7.5 . EC:7.6.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106184 GO:0106183 biolink:MolecularActivity obsolete translocase activity acting on carbohydrates and their derivatives. OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives. EC:7.5.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106183 CHEBI:74243 biolink:ChemicalSubstance 1-octadecanoyl-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74243 chebi_ph7_3 GO:0106182 biolink:MolecularActivity obsolete translocase activity acting on amino acids and peptides. OBSOLETE. Catalysis of the translocation of amino acids and peptides. EC:7.4.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106182 CHEBI:74246 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z,27Z)-3-oxotriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74246 chebi_ph7_3 CL:0002483 biolink:Cell hair follicle melanocyte A melanocyte that produces pigment within the hair follicle. go-plus.json http://purl.obolibrary.org/obo/CL_0002483 GO:0106181 biolink:MolecularActivity obsolete translocase activity acting on inorganic anions OBSOLETE. Catalysis of the translocation of inorganic anions. EC:7.3.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0106181 CHEBI:74245 biolink:ChemicalSubstance 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74245 chebi_ph7_3 GO:0047320 biolink:MolecularActivity D-4-hydroxyphenylglycine transaminase activity Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate. RHEA:15589|KEGG_REACTION:R04234|EC:2.6.1.72|MetaCyc:2.6.1.72-RXN go-plus.json D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity|D-hydroxyphenylglycine aminotransferase activity|D-4-hydroxyphenylglycine aminotransferase activity http://purl.obolibrary.org/obo/GO_0047320 GO:0106188 biolink:MolecularActivity obsolete translocase activity acting on hydrons linked the hydrolysis of a nucleoside triphosphate OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a nucleoside triphosphate. EC:7.1.2.- go-plus.json http://purl.obolibrary.org/obo/GO_0106188 CHEBI:74259 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74259 chebi_ph7_3 GO:0106187 biolink:MolecularActivity obsolete translocase activity acting on hydrons linked to oxidoreductase reactions OBSOLETE. Catalysis of the translocation of hydrons linked to an oxidoreduction reaction. EC:7.1.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0106187 GO:0106186 biolink:CellularComponent cytoplasmic side of plasma membrane, cell tip The leaflet the plasma membrane at the cell tip that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface. go-plus.json http://purl.obolibrary.org/obo/GO_0106186 GO:0106185 biolink:BiologicalProcess histone H3-K37 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 37 of the histone. go-plus.json histone H3 K37 methylation|histone H3K37me|histone lysine H3 K37 methylation http://purl.obolibrary.org/obo/GO_0106185 GO:0106189 biolink:MolecularActivity obsolete translocase activity acting on hydrons linked to the hydrolysis of a diphosphate OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a diphosphate. EC:7.1.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0106189 GO:0047328 biolink:MolecularActivity acyl-phosphate-hexose phosphotransferase activity Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid. EC:2.7.1.61|RHEA:13077|MetaCyc:2.7.1.61-RXN go-plus.json acyl-phosphate:D-hexose phosphotransferase activity|hexose phosphate:hexose phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047328 GO:0047327 biolink:MolecularActivity glycerol-3-phosphate-glucose phosphotransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol. KEGG_REACTION:R00850|RHEA:21288|MetaCyc:2.7.1.142-RXN|EC:2.7.1.142 go-plus.json sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047327 UBERON:0012375 biolink:AnatomicalEntity subserosa A layer of tissue between the muscularis and serosa. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012375 GO:0047326 biolink:MolecularActivity inositol tetrakisphosphate 5-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. Reactome:R-HSA-1855228|MetaCyc:2.7.1.140-RXN|EC:2.7.1.140|RHEA:12717 go-plus.json inositol-tetrakisphosphate 5-kinase activity|inositol 1,3,4,6-tetrakisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity|1D-myo-inositol-tetrakisphosphate 5-kinase activity http://purl.obolibrary.org/obo/GO_0047326 UBERON:0012373 biolink:AnatomicalEntity sympathetic nerve plexus A nerve plexus that is part of a sympathetic nervous system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012373 GO:0047325 biolink:MolecularActivity inositol tetrakisphosphate 1-kinase activity Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. Reactome:R-HSA-1855162|MetaCyc:2.7.1.134-RXN|RHEA:12452|EC:2.7.1.134|Reactome:R-HSA-994137 go-plus.json inositol-tetrakisphosphate 1-kinase activity|inositol 3,4,5,6-tetrakisphosphate 1-kinase activity|1D-myo-inositol-tetrakisphosphate 1-kinase activity|1D-myo-inositol-trisphosphate 6-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 5-kinase activity|ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047325 GO:0047324 biolink:MolecularActivity phosphoenolpyruvate-glycerone phosphotransferase activity Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate. KEGG_REACTION:R01012|MetaCyc:2.7.1.121-RXN|EC:2.7.1.121|RHEA:18381 go-plus.json phosphoenolpyruvate:glycerone phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047324 CHEBI:15937 biolink:ChemicalSubstance trans-5-O-(4-coumaroyl)-D-quinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15937 GO:0047323 biolink:MolecularActivity [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate. MetaCyc:2.7.11.4-RXN|RHEA:17301|Reactome:R-HSA-5693148|EC:2.7.11.4 go-plus.json branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity|[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity|BCK|branched-chain alpha-ketoacid dehydrogenase kinase activity|STK2|BCKD kinase activity|3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity|ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity|BCODH kinase activity|branched-chain 2-oxo acid dehydrogenase kinase activity|branched-chain keto acid dehydrogenase kinase activity http://purl.obolibrary.org/obo/GO_0047323 CHEBI:15936 biolink:ChemicalSubstance aldehydo-D-xylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15936 chebi_ph7_3 GO:0047322 biolink:MolecularActivity [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP. RHEA:23172|EC:2.7.11.31|MetaCyc:2.7.1.109-RXN go-plus.json 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase activity|beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity|HMG-CoA reductase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity|hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity|STK29|ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity|hydroxymethylglutaryl-CoA reductase kinase activity|3-hydroxy-3-methylglutaryl-CoA reductase kinase activity|AMPK|hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity|reductase kinase activity http://purl.obolibrary.org/obo/GO_0047322 UBERON:0012378 biolink:AnatomicalEntity muscle layer of urinary bladder A muscular coat that is part of a urinary bladder. go-plus.json muscular layer of bladder|tunica musculari vesicae|bladder muscular coat|muscular coat of urinary bladder|muscle layer of urinary bladder|muscular coat of bladder|tunica muscularis (vesica urinaria)|muscular layer of urinary bladder http://purl.obolibrary.org/obo/UBERON_0012378 CHEBI:15939 biolink:ChemicalSubstance glycyrrhizinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15939 GO:0047321 biolink:MolecularActivity diphosphate-protein phosphotransferase activity Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein. MetaCyc:2.7.99.1-RXN|EC:2.7.99.1 go-plus.json pyrophosphate-protein phosphotransferase activity|DiPPT|triphosphate-protein phosphotransferase activity|pyrophosphate:protein phosphotransferase activity|diphosphate:microsomal-membrane-protein O-phosphotransferase activity|triphosphate:microsomal-membrane-protein phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047321 CHEBI:15938 biolink:ChemicalSubstance pregnan-21-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15938 chebi_ph7_3 CL:0002496 biolink:Cell intraepithelial lymphocyte A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. go-plus.json intraepithelial T-cell|intraepithelial T cell|IEL http://purl.obolibrary.org/obo/CL_0002496 CHEBI:15933 biolink:ChemicalSubstance UDP-D-apiose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15933 CHEBI:15932 biolink:ChemicalSubstance apiin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15932 CHEBI:15935 biolink:ChemicalSubstance N-acetyl-D-glucosaminylphosphatidylinositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15935 CHEBI:15934 biolink:ChemicalSubstance 5-amino-6-(D-ribitylamino)uracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_15934 chebi_ph7_3 CL:0002499 biolink:Cell spongiotrophoblast cell A trophoblast cell that arises in the junctional zone (basal plate) of the placenta. go-plus.json http://purl.obolibrary.org/obo/CL_0002499 CHEBI:15931 biolink:ChemicalSubstance 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-4-O-sulfo-D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15931 GO:0047329 biolink:MolecularActivity phosphoramidate-hexose phosphotransferase activity Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3. RHEA:10972|EC:2.7.1.62|MetaCyc:2.7.1.62-RXN go-plus.json phosphoramidate-hexose transphosphorylase activity|phosphoramidic-hexose transphosphorylase activity|phosphoramidate:hexose 1-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047329 CHEBI:15930 biolink:ChemicalSubstance atrazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15930 chebi_ph7_3 GO:0106191 biolink:MolecularActivity obsolete translocase activity acting on inogranic cations linked to oxidoreductase reactions OBSOLETE. Catalysis of the translocation of inorganic cations linked to oxidoreductase reactions. EC:7.2.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0106191 GO:0106190 biolink:MolecularActivity obsolete translocase activity acting on hydrons linked to a decarboxylation reaction OBSOLETE. Catalysis of the translocation of hydrons linked to a decarboxylation reaction. EC:7.1.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0106190 CHEBI:74252 biolink:ChemicalSubstance rhizobactin 1021 go-plus.json http://purl.obolibrary.org/obo/CHEBI_74252 GO:0106195 biolink:MolecularActivity obsolete translocase activty acting on inorganic anions linked to oxidoreductase reactions OBSOLETE. Catalysis of the translocation of inorganic anions linked to oxidoreductase reactions. EC:7.3.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0106195 GO:0106194 biolink:MolecularActivity obsolete translocase activity acting on inorganic cations and their chelates linked to a decarboxylation reaction OBSOLETE. Catalysis of the transocation of inorganic cations and their chelates linked to a decarboxylation reaction. EC:7.2.4.- go-plus.json http://purl.obolibrary.org/obo/GO_0106194 CL:0002491 biolink:Cell auditory epithelial cell A specialized cell involved in auditory sensory perception. go-plus.json http://purl.obolibrary.org/obo/CL_0002491 CHEBI:74254 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74254 chebi_ph7_3 GO:0106193 biolink:MolecularActivity obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a diphosphate OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a diphosphate. EC:7.2.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0106193 CL:0002494 biolink:Cell cardiocyte A cell located in the heart, including both muscle and non muscle cells. go-plus.json heart cell http://purl.obolibrary.org/obo/CL_0002494 CHEBI:74257 biolink:ChemicalSubstance FMN-L-threonine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74257 chebi_ph7_3 GO:0106192 biolink:MolecularActivity obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106192 GO:0106111 biolink:BiologicalProcess regulation of mitotic cohesin ssDNA (lagging strand) loading Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. go-plus.json http://purl.obolibrary.org/obo/GO_0106111 GO:0047331 biolink:MolecularActivity diphosphate-glycerol phosphotransferase activity Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate. EC:2.7.1.79|RHEA:13689|KEGG_REACTION:R01044|MetaCyc:2.7.1.79-RXN go-plus.json diphosphate:glycerol 1-phosphotransferase activity|PPi-glycerol phosphotransferase activity|pyrophosphate--glycerol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047331 GO:0047330 biolink:MolecularActivity polyphosphate-glucose phosphotransferase activity Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate. MetaCyc:2.7.1.63-RXN|RHEA:22036|EC:2.7.1.63 go-plus.json polyphosphate:D-glucose 6-phosphotransferase activity|polyphosphate-D-(+)-glucose-6-phosphotransferase activity|polyphosphate glucokinase activity|polyphosphate-glucose 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047330 GO:0106110 biolink:BiologicalProcess vomitoxin biosynthetic process The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats. go-plus.json deoxynivalenol biosynthetic process|DON biosynthetic process|vomitoxin anabolism|vomitoxin synthesis|vomitoxin biosynthesis|vomitoxin formation http://purl.obolibrary.org/obo/GO_0106110 CHEBI:74269 biolink:ChemicalSubstance guanosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74269 chebi_ph7_3 GO:0106115 biolink:BiologicalProcess negative regulation of mitotic cohesin dsDNA (leading strand) loading Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. go-plus.json http://purl.obolibrary.org/obo/GO_0106115 GO:0106114 biolink:BiologicalProcess regulation of mitotic cohesin dsDNA (leading strand) loading Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. go-plus.json http://purl.obolibrary.org/obo/GO_0106114 GO:0106113 biolink:BiologicalProcess positive regulation of mitotic cohesin ssDNA (lagging strand) loading Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. go-plus.json http://purl.obolibrary.org/obo/GO_0106113 CHEBI:142091 biolink:ChemicalSubstance (-)-eremophilene go-plus.json http://purl.obolibrary.org/obo/CHEBI_142091 chebi_ph7_3 GO:0106112 biolink:BiologicalProcess negative regulation of mitotic cohesin ssDNA (lagging strand) loading Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. go-plus.json http://purl.obolibrary.org/obo/GO_0106112 GO:0047339 biolink:MolecularActivity nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate. MetaCyc:2.7.7.28-RXN|EC:2.7.7.28 go-plus.json hexose 1-phosphate guanylyltransferase activity|NDP hexose pyrophosphorylase activity|nucleoside diphosphohexose pyrophosphorylase activity|NTP:hexose-1-phosphate nucleotidyltransferase activity|GTP:hexose-1-phosphate guanylyltransferase activity|guanosine diphosphohexose pyrophosphorylase activity|hexose 1-phosphate nucleotidyltransferase activity|NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|NDP-hexose pyrophosphorylase activity|NDP-hexose diphosphorylase activity|hexose-1-phosphate guanylyltransferase activity|hexose nucleotidylating enzyme activity|nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity|GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity|GDP hexose pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0047339 GO:0106119 biolink:BiologicalProcess negative regulation of sterol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106119 GO:0047338 biolink:MolecularActivity UTP:xylose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate. MetaCyc:2.7.7.11-RXN|EC:2.7.7.11|RHEA:18389 go-plus.json xylose-1-phosphate uridylyltransferase activity|UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity|uridine diphosphoxylose pyrophosphorylase activity|uridylyltransferase, xylose 1-phosphate|xylose 1-phosphate uridylyltransferase activity|UDP-xylose pyrophosphorylase activity|UTP-xylose-1-phosphate uridylyltransferase activity http://purl.obolibrary.org/obo/GO_0047338 GO:0106118 biolink:BiologicalProcess regulation of sterol biosynthetic process Any process that modulates the frequency, rate or extent of a sterol biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106118 GO:0106117 biolink:BiologicalProcess acidocalcisome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. go-plus.json polyphosphate vacuole organization|acidocalcisome organization and biogenesis|metachromatic granule organization|acidocalcisome biogenesis|volutin granule organization|acidocalcisome organisation http://purl.obolibrary.org/obo/GO_0106117 GO:0047337 biolink:MolecularActivity dolichyl-diphosphate-polyphosphate phosphotransferase activity Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate. MetaCyc:2.7.4.20-RXN|RHEA:19417|EC:2.7.4.20 go-plus.json dolichylpyrophosphate:polyphosphate phosphotransferase activity|dolichyl-diphosphate:polyphosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047337 GO:0106116 biolink:BiologicalProcess positive regulation of mitotic cohesin dsDNA (leading strand) loading Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. go-plus.json http://purl.obolibrary.org/obo/GO_0106116 GO:0047336 biolink:MolecularActivity 5-methyldeoxycytidine-5'-phosphate kinase activity Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+). EC:2.7.4.19|KEGG_REACTION:R04235|RHEA:11396|MetaCyc:2.7.4.19-RXN go-plus.json ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047336 GO:0047335 biolink:MolecularActivity 3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate. MetaCyc:2.7.4.17-RXN|EC:2.7.4.17|RHEA:18665 go-plus.json 1,3-diphosphoglycerate-polyphosphate phosphotransferase activity|3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity|diphosphoglycerate-polyphosphate phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047335 GO:0047334 biolink:MolecularActivity diphosphate-fructose-6-phosphate 1-phosphotransferase activity Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate. MetaCyc:2.7.1.90-RXN|RHEA:13613|EC:2.7.1.90 go-plus.json diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity|inorganic pyrophosphate-dependent phosphofructokinase activity|pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity|inorganic pyrophosphate-phosphofructokinase activity|pyrophosphate-fructose 6-phosphate phosphotransferase activity|pyrophosphate-dependent phosphofructo-1-kinase activity|6-phosphofructokinase (diphosphate) activity|6-phosphofructokinase (pyrophosphate) activity|diphosphate-dependent 6-phosphofructose-1-kinase activity|pyrophosphate-dependent 6-phosphofructose-1-kinase activity http://purl.obolibrary.org/obo/GO_0047334 GO:0047333 biolink:MolecularActivity dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+). RHEA:16281|MetaCyc:2.7.1.88-RXN|EC:2.7.1.88|KEGG_REACTION:R03395 go-plus.json ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity|dihydrostreptomycin 6-phosphate kinase (phosphorylating)|dihydrostreptomycin-6-phosphate 3'alpha-kinase activity|ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047333 GO:0047332 biolink:MolecularActivity diphosphate-serine phosphotransferase activity Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate. MetaCyc:2.7.1.80-RXN|RHEA:23764|KEGG_REACTION:R00584|EC:2.7.1.80 go-plus.json diphosphate:L-serine O-phosphotransferase activity|pyrophosphate--serine phosphotransferase activity|pyrophosphate-L-serine phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047332 CL:0002463 biolink:Cell SIRPa-positive adipose dendritic cell An adipose dendritic cell that is SIRPa-positive. go-plus.json DC.SIRPa+.Ad http://purl.obolibrary.org/obo/CL_0002463 CL:0002462 biolink:Cell adipose dendritic cell A F4/80-negative dendritic cell located in adipose tissue. go-plus.json http://purl.obolibrary.org/obo/CL_0002462 UBERON:0036328 biolink:AnatomicalEntity wall of coronary artery go-plus.json coronary arterial wall http://purl.obolibrary.org/obo/UBERON_0036328 CL:0002465 biolink:Cell CD11b-positive dendritic cell A conventional dendritic cell that expresses CD11b (ITGAM). go-plus.json http://purl.obolibrary.org/obo/CL_0002465 CL:0002464 biolink:Cell SIRPa-negative adipose dendritic cell An adipose dendritic cell that is SIRPa-negative. go-plus.json DC.SIRPa-.Ad http://purl.obolibrary.org/obo/CL_0002464 CL:0002467 biolink:Cell Gr1-high myeloid suppressor cell A myeloid suppressor cell that is Gr1-high and CD11c-negative. go-plus.json MDS.Gr1hi http://purl.obolibrary.org/obo/CL_0002467 CHEBI:74260 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74260 chebi_ph7_3 CL:0002469 biolink:Cell MHC-II-negative classical monocyte Gr1-high monocyte that lacks MHC-II receptor complex. go-plus.json Mo.6C+II- http://purl.obolibrary.org/obo/CL_0002469 CL:0002468 biolink:Cell Gr1-low myeloid suppressor cell A myeloid suppressor cell that is Gr1-low and CD11c-positive. go-plus.json MDS.Gr1lo http://purl.obolibrary.org/obo/CL_0002468 CHEBI:74262 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74262 chebi_ph7_3 CHEBI:74261 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74261 chebi_ph7_3 CHEBI:74264 biolink:ChemicalSubstance (8Z,11Z,14Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74264 chebi_ph7_3 CHEBI:74263 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z,35Z)-3-oxooctatriacontapentaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74263 chebi_ph7_3 CHEBI:74266 biolink:ChemicalSubstance N-acylurea go-plus.json http://purl.obolibrary.org/obo/CHEBI_74266 CHEBI:74265 biolink:ChemicalSubstance (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74265 chebi_ph7_3 CHEBI:74268 biolink:ChemicalSubstance N(1)-methylguanosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74268 CL:0002460 biolink:Cell CD8alpha-negative thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8alpha-negative. go-plus.json DC.8-.Th http://purl.obolibrary.org/obo/CL_0002460 CHEBI:74267 biolink:ChemicalSubstance N(1)-methylguanosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74267 GO:0106122 biolink:BiologicalProcess negative regulation of cobalamin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106122 GO:0047342 biolink:MolecularActivity galactose-1-phosphate thymidylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose. EC:2.7.7.32|RHEA:17165|MetaCyc:2.7.7.32-RXN|KEGG_REACTION:R02329 go-plus.json galactose 1-phosphate thymidylyl transferase activity|dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity|thymidine diphosphogalactose pyrophosphorylase activity|dTDP-galactose pyrophosphorylase activity|dTDP-galactose diphosphorylase activity|dTDP galactose pyrophosphorylase activity|thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity http://purl.obolibrary.org/obo/GO_0047342 GO:0047341 biolink:MolecularActivity fucose-1-phosphate guanylyltransferase activity Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose. EC:2.7.7.30|Reactome:R-HSA-6787533|MetaCyc:2.7.7.30-RXN|RHEA:13549|KEGG_REACTION:R01951 go-plus.json GTP:beta-L-fucose-1-phosphate guanylyltransferase activity|guanosine diphosphate L-fucose pyrophosphorylase activity|GDP fucose pyrophosphorylase activity|GTP:L-fucose-1-phosphate guanylyltransferase activity|GDP-fucose pyrophosphorylase activity|GTP:fucose-1-phosphate guanylyltransferase activity|GDP-L-fucose pyrophosphorylase activity|GDP-fucose diphosphorylase activity http://purl.obolibrary.org/obo/GO_0047341 GO:0106121 biolink:BiologicalProcess positive regulation of cobalamin metabolic process Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106121 GO:0106120 biolink:BiologicalProcess positive regulation of sterol biosynthetic process Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0106120 GO:0047340 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0047340 GO:0106126 biolink:CellularComponent reservosome membrane The lipid bilayer surrounding a reservosome. go-plus.json http://purl.obolibrary.org/obo/GO_0106126 GO:0106125 biolink:CellularComponent reservosome matrix A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome. go-plus.json http://purl.obolibrary.org/obo/GO_0106125 GO:0106124 biolink:CellularComponent reservosome lumen The volume enclosed by the membranes of a reservosome. go-plus.json http://purl.obolibrary.org/obo/GO_0106124 GO:0106123 biolink:CellularComponent reservosome A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes. go-plus.json http://purl.obolibrary.org/obo/GO_0106123 UBERON:0036343 biolink:AnatomicalEntity wall of gallbladder go-plus.json gallbladder wall http://purl.obolibrary.org/obo/UBERON_0036343 GO:0047349 biolink:MolecularActivity D-ribitol-5-phosphate cytidylyltransferase activity Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate. KEGG_REACTION:R02921|RHEA:12456|EC:2.7.7.40|MetaCyc:2.7.7.40-RXN go-plus.json CTP:D-ribitol-5-phosphate cytidylyltransferase activity|ribitol 5-phosphate cytidylyltransferase activity|cytidine diphosphate ribitol pyrophosphorylase activity|CDP-ribitol pyrophosphorylase activity|cytidine diphosphoribitol pyrophosphorylase activity|CDP-ribitol diphosphorylase activity|CDP ribitol pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0047349 GO:0106129 biolink:BiologicalProcess positive regulation of store-operated calcium entry Any process that activates or increases the frequency, rate or extent of store-operated calcium entry. go-plus.json http://purl.obolibrary.org/obo/GO_0106129 GO:0047348 biolink:MolecularActivity glycerol-3-phosphate cytidylyltransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate. EC:2.7.7.39|RHEA:13361|MetaCyc:2.7.7.39-RXN|KEGG_REACTION:R00856 go-plus.json CTP:glycerol-3-phosphate cytidylyltransferase activity|CTP:sn-glycerol-3-phosphate cytidylyltransferase activity|CTP:glycerol 3-phosphate cytidylyltransferase activity|Gro-PCT|cytidine diphosphoglycerol pyrophosphorylase activity|CDP-glycerol pyrophosphorylase activity|CDP-glycerol diphosphorylase activity|cytidine diphosphate glycerol pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0047348 GO:0106128 biolink:BiologicalProcess negative regulation of store-operated calcium entry Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry. go-plus.json http://purl.obolibrary.org/obo/GO_0106128 GO:0047347 biolink:MolecularActivity aldose-1-phosphate nucleotidyltransferase activity Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose. EC:2.7.7.37|MetaCyc:2.7.7.37-RXN go-plus.json NDP:aldose-1-phosphate nucleotidyltransferase activity|sugar nucleotide phosphorylase activity|NDP-aldose phosphorylase activity|NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|NDPaldose phosphorylase activity|sugar phosphate nucleotidyltransferase activity|glucose 1-phosphate inosityltransferase activity|NDP-sugar phosphorylase activity|nucleoside diphosphosugar phosphorylase activity|NDP sugar phosphorylase activity|sugar-1-phosphate nucleotidyltransferase activity|nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity http://purl.obolibrary.org/obo/GO_0047347 GO:0047346 biolink:MolecularActivity aldose-1-phosphate adenylyltransferase activity Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose. EC:2.7.7.36|MetaCyc:2.7.7.36-RXN go-plus.json ADP:aldose-1-phosphate adenylyltransferase activity|ADP-sugar phosphorylase activity|sugar-1-phosphate adenylyltransferase activity|ADP sugar phosphorylase activity|ADP-aldose phosphorylase activity|ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity|adenosine diphosphosugar phosphorylase activity|ADPaldose phosphorylase activity|adenosine diphosphate glucose:orthophosphate adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0047346 GO:0047345 biolink:MolecularActivity ribose-5-phosphate adenylyltransferase activity Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate. EC:2.7.7.35|KEGG_REACTION:R01052|MetaCyc:2.7.7.35-RXN|RHEA:14529 go-plus.json adenosine diphosphoribose phosphorylase activity|ADP ribose phosphorylase activity|ADP:ribose-5-phosphate adenylyltransferase activity|ADP:D-ribose-5-phosphate adenylyltransferase activity|ADP-ribose phosphorylase activity http://purl.obolibrary.org/obo/GO_0047345 GO:0047344 biolink:MolecularActivity glucose-1-phosphate guanylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose. EC:2.7.7.34|RHEA:10708|MetaCyc:2.7.7.34-RXN|KEGG_REACTION:R00954 go-plus.json GDP-glucose pyrophosphorylase activity|GDP-glucose diphosphorylase activity|GTP:glucose-1-phosphate guanylyltransferase activity|guanosine diphosphoglucose pyrophosphorylase activity|GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity|GDP glucose pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0047344 GO:0047343 biolink:MolecularActivity glucose-1-phosphate cytidylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate. EC:2.7.7.33|RHEA:18213|MetaCyc:2.7.7.33-RXN|KEGG_REACTION:R00956 go-plus.json CTP:glucose-1-phosphate cytidylyltransferase activity|CTP:D-glucose-1-phosphate cytidylyltransferase activity|cytidine diphosphate glucose pyrophosphorylase activity|CDP-glucose pyrophosphorylase activity|CDP-glucose diphosphorylase activity|cytidine diphosphoglucose pyrophosphorylase activity|CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity|cytidine diphosphate-D-glucose pyrophosphorylase activity|CDP glucose pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0047343 CL:0002474 biolink:Cell lymphoid MHC-II-negative classical monocyte A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high. go-plus.json http://purl.obolibrary.org/obo/CL_0002474 CL:0002473 biolink:Cell MHC-II-high non-classical monocyte Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex. go-plus.json Mo.6C-II+ http://purl.obolibrary.org/obo/CL_0002473 CL:1000245 biolink:Cell posterior lateral line ganglion neuron go-plus.json http://purl.obolibrary.org/obo/CL_1000245 CL:0002476 biolink:Cell bone marrow macrophage A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive. go-plus.json MF.BM http://purl.obolibrary.org/obo/CL_0002476 CL:0002475 biolink:Cell lymphoid MHC-II-negative non-classical monocyte A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high. go-plus.json http://purl.obolibrary.org/obo/CL_0002475 CL:0002478 biolink:Cell F4/80-negative adipose macrophage An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. go-plus.json MF.Autofl.Ad http://purl.obolibrary.org/obo/CL_0002478 CL:0002477 biolink:Cell adipose macrophage A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002477 CHEBI:74271 biolink:ChemicalSubstance 4-demethylwyosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74271 CL:0002479 biolink:Cell F4/80-positive adipose macrophage An adipose macrophage that does not express MHC-II but is F4/80-positive. go-plus.json MF.F480+.Ad http://purl.obolibrary.org/obo/CL_0002479 CHEBI:74273 biolink:ChemicalSubstance 4-demethylwyosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74273 CHEBI:74272 biolink:ChemicalSubstance (R)-3-hydroxydecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74272 chebi_ph7_3 CHEBI:74275 biolink:ChemicalSubstance 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine 5'-phosphate zwitterion residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74275 chebi_ph7_3 CL:0002470 biolink:Cell MHC-II-positive classical monocyte Gr1-high monocyte that has a MHC-II receptor complex. go-plus.json Mo.6c+II http://purl.obolibrary.org/obo/CL_0002470 CHEBI:74276 biolink:ChemicalSubstance (R)-3-hydroxylauroyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74276 chebi_ph7_3 CL:0002472 biolink:Cell MHC-II-low non-classical monocyte Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex. go-plus.json Mo.6C-IIint http://purl.obolibrary.org/obo/CL_0002472 CHEBI:74279 biolink:ChemicalSubstance (R)-3-hydroxyoctanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74279 chebi_ph7_3 CHEBI:74278 biolink:ChemicalSubstance (R)-3-hydroxypalmitoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74278 chebi_ph7_3 CL:0002471 biolink:Cell MHC-II-negative non-classical monocyte Gr1-low non-classical monocyte that lacks expression of a MHC-II complex. go-plus.json Mo.6C-II- http://purl.obolibrary.org/obo/CL_0002471 GO:0047353 biolink:MolecularActivity N-methylphosphoethanolamine cytidylyltransferase activity Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate. MetaCyc:2.7.7.57-RXN|RHEA:10576|EC:2.7.7.57|KEGG_REACTION:R03375 go-plus.json CTP:P-MEA cytidylyltransferase activity|monomethylethanolamine phosphate cytidylyltransferase activity|CTP:N-methylphosphoethanolamine cytidylyltransferase activity|CTP:N-methylethanolamine-phosphate cytidylyltransferase activity http://purl.obolibrary.org/obo/GO_0047353 GO:0047352 biolink:MolecularActivity adenylylsulfate-ammonia adenylyltransferase activity Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate. KEGG_REACTION:R01619|MetaCyc:2.7.7.51-RXN|EC:2.7.7.51|RHEA:19197 go-plus.json adenylylsulphate-ammonia adenylyltransferase activity|APSAT|adenylylsulfate:ammonia adenylyltransferase activity http://purl.obolibrary.org/obo/GO_0047352 GO:0047351 biolink:MolecularActivity guanosine-triphosphate guanylyltransferase activity Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+). MetaCyc:2.7.7.45-RXN|KEGG_REACTION:R00012|EC:2.7.7.45|RHEA:18153 go-plus.json GTP:GTP guanylyltransferase activity http://purl.obolibrary.org/obo/GO_0047351 GO:0047350 biolink:MolecularActivity glucuronate-1-phosphate uridylyltransferase activity Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate. MetaCyc:2.7.7.44-RXN|RHEA:16325|EC:2.7.7.44|KEGG_REACTION:R01381 go-plus.json UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity|UTP:glucuronate-1-phosphate uridylyltransferase activity|UDP-D-glucuronic acid pyrophosphorylase activity|uridine diphosphoglucuronic pyrophosphorylase activity|UDP-glucuronic acid pyrophosphorylase activity|UDP-glucuronate pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0047350 GO:0106130 biolink:MolecularActivity purine phosphoribosyltransferase activity Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0106130 GO:0106137 biolink:MolecularActivity IkappaB kinase complex binding Binding to a IkappaB kinase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0106137 GO:0106136 biolink:BiologicalProcess lectin-induced modified bacterial internalization The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json LIMBI http://purl.obolibrary.org/obo/GO_0106136 GO:0106135 biolink:BiologicalProcess negative regulation of cardiac muscle cell contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0106135 UBERON:0036352 biolink:AnatomicalEntity wall of subclavian artery go-plus.json subclavian arterial wall http://purl.obolibrary.org/obo/UBERON_0036352 GO:0106134 biolink:BiologicalProcess positive regulation of cardiac muscle cell contraction Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0106134 UBERON:0036351 biolink:AnatomicalEntity wall of brachiocephalic artery go-plus.json brachiocephalic arterial wall http://purl.obolibrary.org/obo/UBERON_0036351 CHEBI:15908 biolink:ChemicalSubstance L-threonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15908 CHEBI:15907 biolink:ChemicalSubstance phosphoramidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15907 GO:0106139 biolink:CellularComponent symbiont cell surface The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json endosymbiont cell surface http://purl.obolibrary.org/obo/GO_0106139 GO:0047359 biolink:MolecularActivity 1-alkenyl-2-acylglycerol choline phosphotransferase activity Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP. MetaCyc:2.7.8.22-RXN|EC:2.7.8.22|RHEA:21072 go-plus.json CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity|CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity http://purl.obolibrary.org/obo/GO_0047359 GO:0047358 biolink:MolecularActivity UDP-glucose-glycoprotein glucose phosphotransferase activity Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP. EC:2.7.8.19|RHEA:20181|MetaCyc:2.7.8.19-RXN go-plus.json GlcPTase activity|UDPglucose-glycoprotein glucose phosphotransferase activity|Glc-phosphotransferase activity|UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity|uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity|UDP-glucose:glycoprotein glucose-1-phosphotransferase activity|UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity http://purl.obolibrary.org/obo/GO_0047358 GO:0106138 biolink:MolecularActivity Sec61 translocon complex binding Binding to a Sec61 translocon complex. go-plus.json http://purl.obolibrary.org/obo/GO_0106138 GO:0047357 biolink:MolecularActivity UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP. MetaCyc:2.7.8.18-RXN|KEGG_REACTION:R00504|EC:2.7.8.18|RHEA:22440 go-plus.json galactose-1-phosphotransferase activity|galactosyl phosphotransferase activity|UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity|UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity|uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity|UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047357 CHEBI:15904 biolink:ChemicalSubstance long-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15904 GO:0047356 biolink:MolecularActivity CDP-ribitol ribitolphosphotransferase activity Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP. MetaCyc:2.7.8.14-RXN|EC:2.7.8.14|RHEA:13353 go-plus.json teichoate synthase activity|teichoic-acid synthase activity|polyribitol phosphate polymerase activity|polyribitol phosphate synthetase activity|CDPribitol ribitolphosphotransferase activity|teichoate synthetase activity|CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity|poly(ribitol phosphate) synthetase activity http://purl.obolibrary.org/obo/GO_0047356 CHEBI:15903 biolink:ChemicalSubstance beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_15903 chebi_ph7_3 GO:0047355 biolink:MolecularActivity CDP-glycerol glycerophosphotransferase activity Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP. MetaCyc:2.7.8.12-RXN|RHEA:13565|EC:2.7.8.12 go-plus.json glycerophosphate synthetase activity|teichoic-acid synthase activity|CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity|CDPglycerol glycerophosphotransferase activity|CGPTase activity|poly(glycerol phosphate) polymerase activity|teichoic acid glycerol transferase activity|cytidine diphosphoglycerol glycerophosphotransferase activity http://purl.obolibrary.org/obo/GO_0047355 CHEBI:15906 biolink:ChemicalSubstance demethylmacrocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15906 GO:0047354 biolink:MolecularActivity sphingosine cholinephosphotransferase activity Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine. KEGG_REACTION:R01929|MetaCyc:2.7.8.10-RXN|RHEA:21224|EC:2.7.8.10 go-plus.json CDP-choline-sphingosine cholinephosphotransferase activity|cytidine diphosphocholine-sphingosine cholinephosphotransferase activity|sphingosine choline phosphotransferase activity|phosphorylcholine-sphingosine transferase activity|CDP-choline:sphingosine cholinephosphotransferase activity http://purl.obolibrary.org/obo/GO_0047354 CHEBI:15905 biolink:ChemicalSubstance (R)-4'-phosphopantothenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15905 CL:1000279 biolink:Cell smooth muscle cell of large intestine A smooth muscle cell that is part of the large intestine. go-plus.json non-striated muscle fiber of large intestine http://purl.obolibrary.org/obo/CL_1000279 CHEBI:15900 biolink:ChemicalSubstance trans-2,3-epoxysuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15900 CHEBI:15902 biolink:ChemicalSubstance alpha-D-xylose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15902 CHEBI:15901 biolink:ChemicalSubstance 5,6-dihydrouracil go-plus.json http://purl.obolibrary.org/obo/CHEBI_15901 chebi_ph7_3 CHEBI:74280 biolink:ChemicalSubstance (R)-3-hydroxyhexanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74280 chebi_ph7_3 CL:1000275 biolink:Cell smooth muscle cell of small intestine A smooth muscle cell that is part of the small intestine. go-plus.json non-striated muscle fiber of small intestine http://purl.obolibrary.org/obo/CL_1000275 CL:1000274 biolink:Cell trophectodermal cell go-plus.json trophectoderm cell http://purl.obolibrary.org/obo/CL_1000274 GO:0072319 biolink:BiologicalProcess vesicle uncoating A protein depolymerization process that results in the disassembly of vesicle coat proteins. go-plus.json vesicle coat disassembly http://purl.obolibrary.org/obo/GO_0072319 CHEBI:74282 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74282 chebi_ph7_3 CL:1000272 biolink:Cell lung secretory cell go-plus.json http://purl.obolibrary.org/obo/CL_1000272 GO:0072318 biolink:BiologicalProcess clathrin coat disassembly The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system. go-plus.json clathrin-coated vesicle uncoating|clathrin-coat disassembly|clathrin-coat uncoating http://purl.obolibrary.org/obo/GO_0072318 CHEBI:74281 biolink:ChemicalSubstance trans-2-hexacosenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74281 chebi_ph7_3 GO:0072317 biolink:MolecularActivity obsolete glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus OBSOLETE. Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus. go-plus.json http://purl.obolibrary.org/obo/GO_0072317 CL:1000271 biolink:Cell lung ciliated cell go-plus.json http://purl.obolibrary.org/obo/CL_1000271 GO:0072316 biolink:BiologicalProcess alpha-glucan catabolic process involved in ascospore release from ascus The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus. go-plus.json alpha-glucan catabolism involved in ascospore release from ascus|alpha-glucan breakdown involved in ascospore release from ascus|alpha-glucan degradation involved in ascospore release from ascus http://purl.obolibrary.org/obo/GO_0072316 CHEBI:74283 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74283 chebi_ph7_3 GO:0072315 biolink:BiologicalProcess metanephric glomerular epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072315 CHEBI:74286 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z)-3-oxotriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74286 chebi_ph7_3 GO:0072314 biolink:BiologicalProcess glomerular epithelial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072314 CHEBI:74285 biolink:ChemicalSubstance (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74285 chebi_ph7_3 GO:0106140 biolink:MolecularActivity P-TEFb complex binding Binding to a P-TEFb complex. go-plus.json http://purl.obolibrary.org/obo/GO_0106140 CHEBI:74288 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z)-3-oxodotriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74288 chebi_ph7_3 GO:0072313 biolink:BiologicalProcess metanephric glomerular epithelial cell development The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072313 GO:0072312 biolink:BiologicalProcess metanephric glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072312 CHEBI:74287 biolink:ChemicalSubstance (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74287 chebi_ph7_3 GO:0072311 biolink:BiologicalProcess glomerular epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072311 CHEBI:74289 biolink:ChemicalSubstance (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74289 chebi_ph7_3 GO:0072310 biolink:BiologicalProcess glomerular epithelial cell development The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072310 GO:0047364 biolink:MolecularActivity desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+). RHEA:20281|MetaCyc:2.8.2.24-RXN|KEGG_REACTION:R03214|EC:2.8.2.24 go-plus.json desulphoglucosinolate sulphotransferase activity|3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity|3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity|PAPS-desulfoglucosinolate sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047364 GO:0106144 biolink:MolecularActivity fraxetin 5-hydroxylase activity Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20. EC:1.14.14.164|RHEA:57844 go-plus.json http://purl.obolibrary.org/obo/GO_0106144 GO:0106143 biolink:CellularComponent tRNA (m7G46) methyltransferase complex A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat). go-plus.json Trm8-Trm82 complex|tRNA m7G methylation complex|tRNA (m7G46) methyltransferase http://purl.obolibrary.org/obo/GO_0106143 GO:0047363 biolink:MolecularActivity triglucosylalkylacylglycerol sulfotransferase activity Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate. RHEA:13273|MetaCyc:2.8.2.19-RXN|EC:2.8.2.19 go-plus.json triglucosylalkylacylglycerol sulphotransferase activity|triglucosylmonoalkylmonoacyl sulfotransferase activity|3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047363 GO:0106142 biolink:MolecularActivity rRNA (adenine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA. RHEA:43792|EC:2.1.1.287 go-plus.json 25S rRNA (adenine(645)-N(1))-methyltransferase|25S rRNA m(1)A(645) methyltransferase http://purl.obolibrary.org/obo/GO_0106142 GO:0047362 biolink:MolecularActivity thiosulfate-dithiol sulfurtransferase activity Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite. RHEA:15121|MetaCyc:2.8.1.5-RXN|EC:2.8.1.5 go-plus.json thiosulfate reductase activity|TSR|thiosulphate-dithiol sulphurtransferase activity|thiosulfate:dithioerythritol sulfurtransferase activity http://purl.obolibrary.org/obo/GO_0047362 GO:0106141 biolink:MolecularActivity flavin prenyltransferase activity Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate. EC:2.5.1.129|RHEA:37743 go-plus.json http://purl.obolibrary.org/obo/GO_0106141 GO:0047361 biolink:MolecularActivity phosphomannan mannosephosphotransferase activity Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP. MetaCyc:2.7.8.9-RXN|EC:2.7.8.9 go-plus.json GDP-mannose:phosphomannan mannose phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047361 GO:0047360 biolink:MolecularActivity undecaprenyl-phosphate galactose phosphotransferase activity Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP. MetaCyc:2.7.8.6-RXN|EC:2.7.8.6|KEGG_REACTION:R01535|RHEA:11652 go-plus.json poly(isoprenol)-phosphate galactose phosphotransferase activity|poly(isoprenyl)phosphate galactosephosphatetransferase activity|poly(isoprenol)-phosphate galactosephosphotransferase activity|undecaprenyl phosphate galactosyl-1-phosphate transferase activity|UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity http://purl.obolibrary.org/obo/GO_0047360 GO:0106148 biolink:BiologicalProcess 4-hydroxyindole-3- carbonyl nitrile biosynthesis The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside. go-plus.json http://purl.obolibrary.org/obo/GO_0106148 GO:0106147 biolink:BiologicalProcess fraxetin biosynthesis The chemical reactions and pathways resulting in the formation of fraxetin. go-plus.json http://purl.obolibrary.org/obo/GO_0106147 GO:0106146 biolink:BiologicalProcess sideretin biosynthesis The chemical reactions and pathways resulting in the formation of sideretin. go-plus.json http://purl.obolibrary.org/obo/GO_0106146 UBERON:0036362 biolink:AnatomicalEntity wall of anal canal go-plus.json anal canal wall http://purl.obolibrary.org/obo/UBERON_0036362 GO:0106145 biolink:MolecularActivity scopoletin 8-hydroxylase activity Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2). EC:1.14.11.60|RHEA:57848 go-plus.json http://purl.obolibrary.org/obo/GO_0106145 GO:0047369 biolink:MolecularActivity succinate-hydroxymethylglutarate CoA-transferase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate. EC:2.8.3.13|RHEA:12284|MetaCyc:2.8.3.13-RXN go-plus.json dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity|hydroxymethylglutarate coenzyme A-transferase activity|succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity http://purl.obolibrary.org/obo/GO_0047369 GO:0106149 biolink:MolecularActivity indole-3-carbonyl nitrile 4-hydroxylase activity Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP(+) + H20. EC:1.14.14.165|RHEA:57864 go-plus.json http://purl.obolibrary.org/obo/GO_0106149 GO:0047368 biolink:MolecularActivity UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate. KEGG_REACTION:R04476|MetaCyc:2.8.2.7-RXN|EC:2.8.2.7|RHEA:14337 go-plus.json uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity|UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity|3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity|uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047368 GO:0047367 biolink:MolecularActivity quercetin-3,3'-bissulfate 7-sulfotransferase activity Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate. RHEA:21860|MetaCyc:2.8.2.28-RXN|EC:2.8.2.28 go-plus.json quercetin-3,3'-bissulphate 7-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity|7-sulfotransferase activity|flavonol 7-sulfotransferase activity|PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity http://purl.obolibrary.org/obo/GO_0047367 GO:0047366 biolink:MolecularActivity quercetin-3-sulfate 4'-sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate. RHEA:17205|MetaCyc:2.8.2.27-RXN|EC:2.8.2.27|KEGG_REACTION:R02633 go-plus.json flavonol 4'-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity|PAPS:flavonol 3-sulfate 4'-sulfotransferase activity|quercetin-3-sulphate 4'-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0047366 GO:0047365 biolink:MolecularActivity quercetin-3-sulfate 3'-sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate. MetaCyc:2.8.2.26-RXN|RHEA:22504|EC:2.8.2.26|KEGG_REACTION:R02632 go-plus.json flavonol 3'-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity|PAPS:flavonol 3-sulfate 3'-sulfotransferase activity|3'-sulfotransferase activity|quercetin-3-sulphate 3'-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0047365 CL:0002454 biolink:Cell Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive. go-plus.json DC.8-4-11b+|spleen double-negative dendritic cell http://purl.obolibrary.org/obo/CL_0002454 CL:0002453 biolink:Cell oligodendrocyte precursor cell The cell type from which oligodendrocytes develop. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons. go-plus.json http://purl.obolibrary.org/obo/CL_0002453 CL:0002456 biolink:Cell CD8_alpha-positive plasmactyoid dendritic cell A CD11c-low plasmacytoid dendritic cell that is CD8alpha-positive and CD4-positive. go-plus.json DC.pDC.8+ http://purl.obolibrary.org/obo/CL_0002456 CHEBI:74291 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74291 chebi_ph7_3 CL:0002455 biolink:Cell CD8_alpha-negative plasmactyoid dendritic cell A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4-positive. go-plus.json DC.pDC.8- http://purl.obolibrary.org/obo/CL_0002455 CHEBI:74290 biolink:ChemicalSubstance (19Z,22Z,25Z,28Z)-3-oxotetratriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74290 chebi_ph7_3 GO:0072309 biolink:BiologicalProcess mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0072309 GO:0072308 biolink:BiologicalProcess negative regulation of metanephric nephron tubule epithelial cell differentiation Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0072308 CHEBI:74293 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74293 chebi_ph7_3 CL:0002457 biolink:Cell epidermal Langerhans cell A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002457 CHEBI:74292 biolink:ChemicalSubstance (21Z,24Z,27Z,30Z)-3-oxohexatriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74292 chebi_ph7_3 GO:0072307 biolink:BiologicalProcess regulation of metanephric nephron tubule epithelial cell differentiation Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0072307 GO:0072306 biolink:BiologicalProcess positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros. go-plus.json positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072306 GO:0072305 biolink:BiologicalProcess negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros. go-plus.json negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072305 CHEBI:74294 biolink:ChemicalSubstance (23Z,26Z,29Z,32Z)-3-oxooctatriacontatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74294 chebi_ph7_3 GO:0072304 biolink:BiologicalProcess regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros. go-plus.json regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis|regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis http://purl.obolibrary.org/obo/GO_0072304 CHEBI:74297 biolink:ChemicalSubstance (9Z,11E)-octadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74297 chebi_ph7_3 GO:0072303 biolink:BiologicalProcess positive regulation of glomerular metanephric mesangial cell proliferation Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0072303 CHEBI:74296 biolink:ChemicalSubstance (11E)-octadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74296 chebi_ph7_3 GO:0072302 biolink:BiologicalProcess negative regulation of metanephric glomerular mesangial cell proliferation Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0072302 CHEBI:74299 biolink:ChemicalSubstance geranyllinalool go-plus.json http://purl.obolibrary.org/obo/CHEBI_74299 chebi_ph7_3 GO:0106151 biolink:MolecularActivity CNBH domain intrinsic ligand binding Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0106151 GO:0106150 biolink:BiologicalProcess zearalenone biosynthetic process The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals. go-plus.json http://purl.obolibrary.org/obo/GO_0106150 GO:0072301 biolink:BiologicalProcess regulation of metanephric glomerular mesangial cell proliferation Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0072301 CHEBI:74298 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74298 chebi_ph7_3 GO:0072300 biolink:BiologicalProcess positive regulation of metanephric glomerulus development Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0072300 OBO:GOCHE_33290 biolink:OntologyClass substance with food role go-plus.json http://purl.obolibrary.org/obo/GOCHE_33290 3_STAR GO:0052049 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type III secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type III secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052049 GO:0052048 biolink:BiologicalProcess obsolete interaction with host via secreted substance OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json interaction with host via secreted substance during symbiotic interaction|interaction with host via secreted substance involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052048 GO:0052043 biolink:BiologicalProcess modification by symbiont of host cellular component The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052043 GO:0052042 biolink:BiologicalProcess positive regulation by symbiont of host programmed cell death Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of host programmed cell death|induction by symbiont of host programmed cell death|activation by organism of programmed cell death in other organism during symbiotic interaction|stimulation by symbiont of host programmed cell death|induction of non-apoptotic programmed cell death by other organism|enhancement of host programmed cell death|induction by organism of programmed cell death in other organism during symbiotic interaction|activation by symbiont of host programmed cell death|positive regulation by symbiont of host non-apoptotic programmed cell death|enhancement of host programmed cell death by organism|induction by organism of programmed cell death in other organism involved in symbiotic interaction|induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|pathogenesis|activation by organism of non-apoptotic programmed cell death in other organism|upregulation by symbiont of host programmed cell death http://purl.obolibrary.org/obo/GO_0052042 GO:0052041 biolink:BiologicalProcess negative regulation by symbiont of host programmed cell death Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json suppression by symbiont of host PCD|down-regulation by symbiont of host programmed cell death|suppression by symbiont of host programmed cell death|inhibition of host programmed cell death|downregulation by symbiont of host programmed cell death|down regulation by symbiont of host programmed cell death|inhibition by symbiont of host programmed cell death http://purl.obolibrary.org/obo/GO_0052041 GO:0052040 biolink:BiologicalProcess modulation by symbiont of host programmed cell death Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of host PCD|modulation by symbiont of host non-apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052040 GO:0052047 biolink:BiologicalProcess obsolete symbiotic process mediated by secreted substance OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction. go-plus.json interaction with other organism via secreted substance during symbiotic interaction|interaction with other organism via secreted substance involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052047 GO:0052046 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via secreted substance OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by one of the organisms. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification of host morphology or physiology via effector molecule|modification of host morphology or physiology via ellicitor http://purl.obolibrary.org/obo/GO_0052046 GO:0052045 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052045 GO:0052044 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052044 GO:0052059 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052059 GO:0052050 biolink:BiologicalProcess obsolete interaction with host via substance secreted by type IV secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type IV secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052050 GO:0052054 biolink:BiologicalProcess obsolete negative regulation by symbiont of host peptidase activity OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host protease activity|down-regulation by symbiont of host protease activity|inhibition of host protease activity|downregulation by symbiont of host protease activity|down regulation by symbiont of host protease activity|inhibition by symbiont of host protease activity http://purl.obolibrary.org/obo/GO_0052054 GO:0052053 biolink:BiologicalProcess negative regulation by symbiont of host catalytic activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json downregulation by symbiont of host enzyme activity|down regulation by symbiont of host enzyme activity|inhibition by symbiont of host enzyme activity|negative regulation by symbiont of host molecular function|negative regulation by symbiont of host enzyme activity|down-regulation by symbiont of host enzyme activity|inhibition of host enzyme activity http://purl.obolibrary.org/obo/GO_0052053 GO:0052052 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type II secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type II secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052052 GO:0052051 biolink:BiologicalProcess obsolete interaction with host via protein secreted by type II secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type II secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052051 GO:0052058 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via substance secreted by type IV secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type IV secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052058 GO:0052057 biolink:BiologicalProcess obsolete modification by symbiont of host morphology or physiology via protein secreted by type III secretion system OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type III secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052057 GO:0052056 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052056 GO:0052055 biolink:BiologicalProcess modulation by symbiont of host molecular function The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification by symbiont of host molecular function|modification by symbiont of host protein function http://purl.obolibrary.org/obo/GO_0052055 RO:0000092 biolink:OntologyClass disposition of inverse of has disposition RO:0000092 go-plus.json http://purl.obolibrary.org/obo/RO_0000092 RO:0000091 biolink:OntologyClass has disposition a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence RO:0000091 go-plus.json http://purl.obolibrary.org/obo/RO_0000091 GO:0003098 biolink:BiologicalProcess tubuloglomerular feedback The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus. Wikipedia:Tubuloglomerular_feedback go-plus.json http://purl.obolibrary.org/obo/GO_0003098 GO:0003097 biolink:BiologicalProcess renal water transport The directed movement of water (H2O) by the renal system. go-plus.json http://purl.obolibrary.org/obo/GO_0003097 GO:0003099 biolink:BiologicalProcess positive regulation of the force of heart contraction by chemical signal Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. go-plus.json positive regulation of the force of heart muscle contraction by chemical signal http://purl.obolibrary.org/obo/GO_0003099 GO:0003094 biolink:BiologicalProcess glomerular filtration The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein. go-plus.json http://purl.obolibrary.org/obo/GO_0003094 GO:0003093 biolink:BiologicalProcess regulation of glomerular filtration Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0003093 GO:0003096 biolink:BiologicalProcess renal sodium ion transport The directed movement of sodium ions (Na+) by the renal system. go-plus.json http://purl.obolibrary.org/obo/GO_0003096 GO:0003095 biolink:BiologicalProcess pressure natriuresis The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis). go-plus.json http://purl.obolibrary.org/obo/GO_0003095 GO:0052061 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052061 GO:0052060 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052060 GO:0052065 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052065 GO:0052064 biolink:BiologicalProcess induction by symbiont of defense-related host reactive oxygen species production The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json activation by symbiont of defense-related host metabolic burst|induction by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host ROS production|upregulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host reactive oxidative species production|induction by symbiont of defense-related host oxidative burst|activation by symbiont of defense-related host respiratory burst|induction by symbiont of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host reactive oxygen intermediate production|induction by symbiont of defense-related host active oxygen species production|up regulation by symbiont of defense-related host reactive oxygen species production|positive regulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host reactive oxidative species production|positive regulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host oxidative burst|induction by symbiont of defense-related host metabolic burst|stimulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host ROI production|up-regulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host AOS production http://purl.obolibrary.org/obo/GO_0052064 GO:0052063 biolink:BiologicalProcess induction by symbiont of defense-related host nitric oxide production The activation by a symbiont of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of defense-related host nitric oxide production|upregulation by symbiont of defense-related host nitric oxide production|induction by organism of defense-related host NO production|up-regulation by symbiont of defense-related host nitric oxide production|positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|activation by organism of defense-related host NO production|stimulation by symbiont of defense-related host nitric oxide production|activation by symbiont of defense-related host nitric oxide production|positive regulation by symbiont of defense-related host nitric oxide production|induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|positive regulation by organism of defense-related host NO production|up regulation by symbiont of defense-related host nitric oxide production http://purl.obolibrary.org/obo/GO_0052063 GO:0052062 biolink:BiologicalProcess induction by symbiont of host phytoalexin production The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of phytoalexin production in other organism involved in symbiotic interaction|activation by organism of host phytoalexin production http://purl.obolibrary.org/obo/GO_0052062 GO:0052069 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052069 GO:0052068 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052068 GO:0052067 biolink:BiologicalProcess antiphagocytosis Any process in which a symbiont avoids phagocytosis by a host cell, for example a phagocyte or a macrophage. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of entry into host via host phagocytosis|down regulation by symbiont of entry into host cell via phagocytosis|negative regulation by organism of entry into cell of other organism via phagocytosis involved in symbiotic interaction|negative regulation by organism of entry into host cell via host phagocytosis|modulation by symbiont of entry into host via phagocytosis|downregulation by symbiont of entry into host cell via phagocytosis|phagocytosis avoidence|down-regulation by symbiont of entry into host cell via phagocytosis|negative regulation by symbiont of entry into host cell via phagocytosis|inhibition by symbiont of entry into host cell via phagocytosis http://purl.obolibrary.org/obo/GO_0052067 GO:0052066 biolink:BiologicalProcess obsolete entry of symbiont into host cell by promotion of host phagocytosis OBSOLETE. The invasion by a symbiont of a host organism cell by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json penetration of symbiont into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction|entry of organism into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction|penetration of organism into host cell by promotion of host phagocytosis http://purl.obolibrary.org/obo/GO_0052066 RO:0000081 biolink:OntologyClass role of a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence RO:0000081 go-plus.json http://purl.obolibrary.org/obo/RO_0000081 RO:0000080 biolink:OntologyClass quality of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence RO:0000080 go-plus.json http://purl.obolibrary.org/obo/RO_0000080 RO:0000085 biolink:OntologyClass has function a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence RO:0000085 go-plus.json http://purl.obolibrary.org/obo/RO_0000085 RO:0000087 biolink:OntologyClass has role a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence RO:0000087 go-plus.json http://purl.obolibrary.org/obo/RO_0000087 RO:0000086 biolink:OntologyClass has quality a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence RO:0000086 go-plus.json http://purl.obolibrary.org/obo/RO_0000086 RO:0000079 biolink:OntologyClass function of a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence RO:0000079 go-plus.json http://purl.obolibrary.org/obo/RO_0000079 GO:0052072 biolink:BiologicalProcess induction by symbiont of defense-related host salicylic acid-mediated signal transduction pathway Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|induction by organism of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|activation by organism of defense-related host SA-mediated signal transduction pathway|up regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|activation by organism of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related host SA-mediated signal transduction pathway|stimulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|up-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|induction by organism of defense-related host SA-mediated signal transduction pathway|activation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related host salicylic acid-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052072 GO:0052071 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052071 GO:0052070 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052070 GO:0052076 biolink:BiologicalProcess induction by symbiont of host ethylene-mediated defense response Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json up-regulation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|upregulation by symbiont of host ethylene-mediated defense response|positive regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host ethylene-mediated defense response|positive regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|activation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of host ethylene-mediated defense response|stimulation by symbiont of host ethylene-mediated defense response http://purl.obolibrary.org/obo/GO_0052076 GO:0052075 biolink:BiologicalProcess positive regulation by symbiont of host jasmonic acid-mediated defense response Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json stimulation by symbiont of host jasmonic acid-mediated defense response|up-regulation by symbiont of host jasmonic acid-mediated defense response|activation by symbiont of host jasmonic acid-mediated defense response|induction by organism of host JA-mediated defense response|induction by organism of host jasmonic acid-mediated defense response|up regulation by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|positive regulation by organism of host JA-mediated defense response|upregulation by symbiont of host jasmonic acid-mediated defense response http://purl.obolibrary.org/obo/GO_0052075 GO:0052074 biolink:BiologicalProcess positive regulation by symbiont of host salicylic acid-mediated defense response Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json upregulation by symbiont of host salicylic acid-mediated defense response|induction by organism of host salicylic acid-mediated defense response|positive regulation by organism of host SA-mediated defense response|positive regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host salicylic acid-mediated defense response|activation by symbiont of host salicylic acid-mediated defense response|induction by organism of host SA-mediated defense response|stimulation by symbiont of host salicylic acid-mediated defense response|up-regulation by symbiont of host salicylic acid-mediated defense response http://purl.obolibrary.org/obo/GO_0052074 GO:0052073 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052073 GO:0052079 biolink:BiologicalProcess induction by symbiont of defense-related host MAP kinase-mediated signal transduction pathway Any process in which an organism activates, maintains or increases the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of defense-related host MAP kinase-mediated signal transduction pathway|upregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|stimulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|activation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|up-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|upregulation by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|positive regulation by organism of defense-related host MAPK-mediated signal transduction pathway|induction by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|up regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052079 GO:0052078 biolink:BiologicalProcess suppression by symbiont of defense-related host MAP kinase-mediated signal transduction pathway Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json inhibition by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|suppression by organism of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host MAPK-mediated signal transduction pathway|negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|down-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|downregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|down regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052078 GO:0052077 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052077 GO:0003079 biolink:BiologicalProcess obsolete positive regulation of natriuresis OBSOLETE. Any process that activates or increases the frequency, rate or extent of natriuresis. go-plus.json positive regulation of natriuresis http://purl.obolibrary.org/obo/GO_0003079 GO:0003076 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003076 GO:0003075 biolink:BiologicalProcess renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system. go-plus.json renal regulation of systemic arterial blood pressure by vasodilation of the peripheral vascular system http://purl.obolibrary.org/obo/GO_0003075 GO:0003078 biolink:BiologicalProcess obsolete regulation of natriuresis OBSOLETE. Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion. go-plus.json regulation of natriuresis http://purl.obolibrary.org/obo/GO_0003078 GO:0003077 biolink:BiologicalProcess obsolete negative regulation of diuresis OBSOLETE. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion. go-plus.json negative regulation of diuresis http://purl.obolibrary.org/obo/GO_0003077 GO:0003072 biolink:BiologicalProcess renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature. go-plus.json regulation of systemic arterial blood pressure by renal control of peripheral vascular resistence|renal regulation of systemic arterial blood pressure by control of peripheral vascular resistence http://purl.obolibrary.org/obo/GO_0003072 GO:0003071 biolink:BiologicalProcess renal system process involved in regulation of systemic arterial blood pressure Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. go-plus.json renal control of blood pressure|renal regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003071 GO:0003074 biolink:BiologicalProcess obsolete regulation of diuresis OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion. go-plus.json regulation of diuresis http://purl.obolibrary.org/obo/GO_0003074 GO:0003073 biolink:BiologicalProcess regulation of systemic arterial blood pressure The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. go-plus.json http://purl.obolibrary.org/obo/GO_0003073 GO:0003081 biolink:BiologicalProcess regulation of systemic arterial blood pressure by renin-angiotensin The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system. go-plus.json blood pressure regulation by renin-angiotensin http://purl.obolibrary.org/obo/GO_0003081 GO:0003080 biolink:BiologicalProcess obsolete negative regulation of natriuresis OBSOLETE. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion. go-plus.json negative regulation of natriuresis http://purl.obolibrary.org/obo/GO_0003080 GO:0052083 biolink:BiologicalProcess suppression by symbiont of host cell-mediated immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of host cell-based immune response|downregulation by symbiont of host cell-mediated immune response|down regulation by symbiont of host cell-mediated immune response|inhibition by symbiont of host cell-mediated immune response|negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|down-regulation by symbiont of host cell-mediated immune response http://purl.obolibrary.org/obo/GO_0052083 GO:0052082 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052082 GO:0052081 biolink:BiologicalProcess modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of defense-related host SA-mediated signal transduction pathway by organism|modulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052081 GO:0052080 biolink:BiologicalProcess modulation by symbiont of host innate immune response MAPK kinase signaling Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation of defense-related host MAPK-mediated signal transduction pathway by organism|modulation of defense-related host mitogen activated protein kinase-mediated signal transduction pathway by organism|modulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052080 GO:0052087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052087 GO:0052086 biolink:BiologicalProcess suppression by symbiont of host B-cell mediated immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json down regulation by symbiont of host B-cell mediated immune response|inhibition by symbiont of host B-cell mediated immune response|negative regulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction|down-regulation by symbiont of host B-cell mediated immune response|downregulation by symbiont of host B-cell mediated immune response http://purl.obolibrary.org/obo/GO_0052086 GO:0052085 biolink:BiologicalProcess suppression by symbiont of host T-cell mediated immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host T-cell mediated immune response|down-regulation by symbiont of host T-cell mediated immune response|downregulation by symbiont of host T-cell mediated immune response|down regulation by symbiont of host T-cell mediated immune response|inhibition by symbiont of host T-cell mediated immune response|negative regulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052085 CHEBI:4031 biolink:ChemicalSubstance cyclosporin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_4031 chebi_ph7_3 GO:0052084 biolink:BiologicalProcess modulation by symbiont of host ethylene-mediated defense response Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052084 GO:0052089 biolink:BiologicalProcess modulation by symbiont of host salicylic acid-mediated defense response Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of host SA-mediated defense response|modulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052089 GO:0052088 biolink:BiologicalProcess symbiont defense to host-produced jasmonic acid Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|downregulation by symbiont of host jasmonic acid-mediated defense response|suppression by symbiont of host jasmonic acid-mediated defense response|upregulation by organism of defense-related host SA-mediated signal transduction pathway|upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|down regulation by symbiont of host jasmonic acid-mediated defense response|modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|induction by organism of defense-related host SA-mediated signal transduction pathway|induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway|inhibition by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|suppression by organism of host JA-mediated defense response|up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|modulation by organism of host JA-mediated defense response|activation by organism of defense-related host SA-mediated signal transduction pathway|negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|down-regulation by symbiont of host jasmonic acid-mediated defense response|negative regulation by symbiont of host jasmonic acid-mediated defense response|stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052088 GO:0003087 biolink:BiologicalProcess positive regulation of the force of heart contraction by neuronal epinephrine The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction. go-plus.json increased force of heart contraction by neuronal adrenaline|positive regulation of heart contraction by adrenaline|increased force of heart contraction by epinephrine released from the nerve endings|positive regulation of heart contraction by neuronal epinephrine|increased force of heart contraction by neuronal epinephrine http://purl.obolibrary.org/obo/GO_0003087 GO:0003086 biolink:BiologicalProcess regulation of systemic arterial blood pressure by local renal renin-angiotensin The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen. go-plus.json http://purl.obolibrary.org/obo/GO_0003086 GO:0003089 biolink:BiologicalProcess positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream. go-plus.json increased force of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating epinephrine-norepinephrine|increased force of heart contraction by epinephrine-norepinephrine in the blood stream|increased force of heart contraction by circulating epinephrine-norepinephrine http://purl.obolibrary.org/obo/GO_0003089 GO:0003088 biolink:BiologicalProcess positive regulation of the force of heart contraction by circulating epinephrine The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction. go-plus.json positive regulation of heart contraction by circulating epinephrine|increased force of heart contraction by circulating adrenaline|increased force of heart contraction by epinephrine in the bloodstream|positive regulation of heart contraction by circulating adrenaline http://purl.obolibrary.org/obo/GO_0003088 CL:1000768 biolink:Cell kidney connecting tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000768 GO:0003083 biolink:BiologicalProcess negative regulation of renal output by angiotensin The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney. go-plus.json angiotensin-mediated negative regulation of renal output|angiotensin mediated negative regulation of renal output http://purl.obolibrary.org/obo/GO_0003083 GO:0003082 biolink:BiologicalProcess obsolete positive regulation of renal output by angiotensin OBSOLETE. Any process in which angiotensin directly increases the rate of natriuresis and diuresis in the kidney. go-plus.json angiotensin-mediated positive regulation of renal output|positive regulation of renal output by angiotensin|angiotensin mediated positive regulation of renal output http://purl.obolibrary.org/obo/GO_0003082 GO:0003085 biolink:BiologicalProcess negative regulation of systemic arterial blood pressure The process that reduces the force with which blood travels through the systemic arterial circulatory system. go-plus.json http://purl.obolibrary.org/obo/GO_0003085 GO:0003084 biolink:BiologicalProcess positive regulation of systemic arterial blood pressure The process that increases the force with which blood travels through the systemic arterial circulatory system. go-plus.json http://purl.obolibrary.org/obo/GO_0003084 GO:0003090 biolink:BiologicalProcess positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings. go-plus.json increased force of heart contraction by neuronal adrenaline-noradrenaline|positive regulation of heart contraction by adrenaline-noradrenaline|positive regulation of heart contraction by epinephrine-norepinephrine|increased force of heart contraction by epinephrine-norepinephrine released from the nerve endings|increased force of heart contraction by neuronal epinephrine-norepinephrine http://purl.obolibrary.org/obo/GO_0003090 GO:0052090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052090 GO:0003092 biolink:BiologicalProcess renal water retention The process in which renal water excretion is decreased. go-plus.json negative regulation of renal water excretion http://purl.obolibrary.org/obo/GO_0003092 RO:0000057 biolink:OntologyClass has participant a relation between a process and a continuant, in which the continuant is somehow involved in the process RO:0000057 go-plus.json http://purl.obolibrary.org/obo/RO_0000057 GO:0003091 biolink:BiologicalProcess renal water homeostasis Renal process involved in the maintenance of an internal steady state of water in the body. go-plus.json water homeostasis by the renal system http://purl.obolibrary.org/obo/GO_0003091 GO:0052094 biolink:BiologicalProcess formation of haustorium for nutrient acquisition The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation by symbiont of haustorium for nutrient acquisition from host|formation by organism of haustorium for nutrient acquisition from host|formation by organism of haustoria for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0052094 GO:0052093 biolink:BiologicalProcess formation of specialized structure for nutrient acquisition The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation by symbiont of specialized structure for nutrient acquisition from host|formation of specialized structure for nutrient acquisition from host|formation by organism of specialized structure for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0052093 GO:0052092 biolink:BiologicalProcess positive regulation by symbiont of nutrient release from host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json promotion of nutrient release from host|up regulation by symbiont of nutrient release from host|upregulation by symbiont of nutrient release from host|stimulation by symbiont of nutrient release from host|up-regulation by symbiont of nutrient release from host|activation by symbiont of nutrient release from host http://purl.obolibrary.org/obo/GO_0052092 GO:0052091 biolink:BiologicalProcess modulation by symbiont of nutrient release from host Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052091 GO:0052098 biolink:BiologicalProcess formation by host of specialized structure for nutrient acquisition from symbiont The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052098 GO:0052097 biolink:BiologicalProcess obsolete interspecies quorum sensing OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0052097 GO:0052096 biolink:BiologicalProcess formation of syncytium involving giant cell for nutrient acquisition The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json formation by symbiont of syncytium involving giant cell for nutrient acquisition from host|formation by organism of syncytium involving giant cell for nutrient acquisition from host http://purl.obolibrary.org/obo/GO_0052096 GO:0052095 biolink:BiologicalProcess formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a second organism, where the two organisms are in a symbiotic interaction. go-plus.json formation of specialized structure for nutrient acquisition from other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052095 CHEBI:4047 biolink:ChemicalSubstance L-cysteinylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_4047 GO:0052099 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052099 GO:0003058 biolink:BiologicalProcess hormonal regulation of the force of heart contraction The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. go-plus.json hormonal regulation of the force of heart muscle contraction|hormonal cardiac inotropy http://purl.obolibrary.org/obo/GO_0003058 GO:0003057 biolink:BiologicalProcess regulation of the force of heart contraction by chemical signal The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. go-plus.json regulation of the force of heart muscle contraction by chemical signal|chemical cardiac inotropy http://purl.obolibrary.org/obo/GO_0003057 GO:0003059 biolink:BiologicalProcess positive regulation of the force of heart contraction by epinephrine The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction. go-plus.json positive regulation of heart contraction by adrenaline|epinephrine cardiac inotropy|adrenaline cardiac inotropy|increased force of heart contraction by epinephrine|adrenaline regulation of the strength of heart muscle contraction|positive regulation of heart contraction by epinephrine http://purl.obolibrary.org/obo/GO_0003059 GO:0003054 biolink:BiologicalProcess circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours. go-plus.json SCN regulation of blood pressure|master pacemaker clock regulation of blood pressure http://purl.obolibrary.org/obo/GO_0003054 RO:0000052 biolink:OntologyClass characteristic of a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence RO:0000052 go-plus.json http://purl.obolibrary.org/obo/RO_0000052 GO:0003053 biolink:BiologicalProcess circadian regulation of heart rate Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours. go-plus.json circadian regulation of heart contraction rate http://purl.obolibrary.org/obo/GO_0003053 GO:0003056 biolink:BiologicalProcess regulation of vascular associated smooth muscle contraction Any process that increases the frequency, rate or extent of vascular smooth muscle contraction. go-plus.json regulation of vascular smooth muscle contraction http://purl.obolibrary.org/obo/GO_0003056 GO:0003055 biolink:BiologicalProcess circadian regulation of heart rate by the suprachiasmatic nucleus The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours. go-plus.json circadian regulation of heart contraction rate by the suprachiasmatic nucleus|SCN regulation of heart rate|master pacemaker clock regulation of heart rate http://purl.obolibrary.org/obo/GO_0003055 RO:0000056 biolink:OntologyClass participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process RO:0000056 go-plus.json http://purl.obolibrary.org/obo/RO_0000056 GO:0003050 biolink:BiologicalProcess regulation of systemic arterial blood pressure by atrial natriuretic peptide The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide. go-plus.json blood pressure regulation by ANP|blood pressure regulation by atrial natriuretic peptide http://purl.obolibrary.org/obo/GO_0003050 GO:0003052 biolink:BiologicalProcess circadian regulation of systemic arterial blood pressure Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours. go-plus.json http://purl.obolibrary.org/obo/GO_0003052 RO:0000053 biolink:OntologyClass bearer of Inverse of characteristic_of RO:0000053 go-plus.json http://purl.obolibrary.org/obo/RO_0000053 GO:0003051 biolink:BiologicalProcess angiotensin-mediated drinking behavior The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst. go-plus.json angiotensin mediated drinking behavior http://purl.obolibrary.org/obo/GO_0003051 OBO:GOCHE_33280 biolink:OntologyClass substance with molecular messenger role go-plus.json http://purl.obolibrary.org/obo/GOCHE_33280 3_STAR GO:0003069 biolink:BiologicalProcess acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure. go-plus.json vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003069 OBO:GOCHE_33284 biolink:OntologyClass substance with nutrient role go-plus.json http://purl.obolibrary.org/obo/GOCHE_33284 3_STAR GO:0003068 biolink:BiologicalProcess regulation of systemic arterial blood pressure by acetylcholine The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter. go-plus.json blood pressure regulation by acetylcholine http://purl.obolibrary.org/obo/GO_0003068 OBO:GOCHE_33281 biolink:OntologyClass substance with antimicrobial agent role go-plus.json http://purl.obolibrary.org/obo/GOCHE_33281 3_STAR GO:0003065 biolink:BiologicalProcess positive regulation of heart rate by epinephrine The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction. go-plus.json adrenaline regulation of the rate of heart muscle contraction|adrenaline cardiac chronotropy|positive regulation of heart contraction rate by epinephrine|epinephrine cardiac chronotropy|positive regulation of heart rate by adrenaline http://purl.obolibrary.org/obo/GO_0003065 GO:0003064 biolink:BiologicalProcess regulation of heart rate by hormone The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. go-plus.json regulation of the rate of heart contraction by hormone|hormonal cardiac chronotropy http://purl.obolibrary.org/obo/GO_0003064 GO:0003067 biolink:BiologicalProcess circadian regulation of systemic arterial blood pressure by hormone The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. go-plus.json http://purl.obolibrary.org/obo/GO_0003067 GO:0003066 biolink:BiologicalProcess positive regulation of heart rate by norepinephrine The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction. go-plus.json positive regulation of heart contraction rate by norepinephrine|noradrenaline cardiac chronotropy|noradrenaline regulation of the rate of heart muscle contraction|norepinephrine cardiac chronotropy|positive regulation of heart rate by adrenaline http://purl.obolibrary.org/obo/GO_0003066 GO:0003061 biolink:BiologicalProcess positive regulation of the force of heart contraction by norepinephrine The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction. go-plus.json norepinephrine cardiac inotropy|noradrenaline cardiac inotropy|increased force of heart contraction by adrenaline|positive regulation of heart contraction by adrenaline|noradrenaline regulation of the strength of heart muscle contraction|increased force of heart contraction by norepinephrine|positive regulation of heart contraction by norepinephrine http://purl.obolibrary.org/obo/GO_0003061 CHEBI:146022 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146022 chebi_ph7_3 GO:0003060 biolink:BiologicalProcess negative regulation of the force of heart contraction by acetylcholine The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction. go-plus.json decreased force of heart contraction by acetylcholine http://purl.obolibrary.org/obo/GO_0003060 CHEBI:146021 biolink:ChemicalSubstance N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146021 chebi_ph7_3 GO:0003063 biolink:BiologicalProcess negative regulation of heart rate by acetylcholine The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction. go-plus.json negative regulation of heart contraction rate by acetylcholine http://purl.obolibrary.org/obo/GO_0003063 GO:0003062 biolink:BiologicalProcess regulation of heart rate by chemical signal The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine. go-plus.json chemical cardiac chronotropy|chemical signal regulation of heart rate|chemical signal regulation of heart contraction rate http://purl.obolibrary.org/obo/GO_0003062 CHEBI:4027 biolink:ChemicalSubstance cyclophosphamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_4027 chebi_ph7_3 GO:0003070 biolink:BiologicalProcess regulation of systemic arterial blood pressure by neurotransmitter The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003070 OBO:GOCHE_23888 biolink:OntologyClass substance with drug role go-plus.json http://purl.obolibrary.org/obo/GOCHE_23888 3_STAR CHEBI:29656 biolink:ChemicalSubstance neomethymycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29656 CHEBI:4083 biolink:ChemicalSubstance D-4-hydroxy-2-oxoglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4083 CHEBI:29658 biolink:ChemicalSubstance oleandolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29658 chebi_ph7_3 GO:0042640 biolink:BiologicalProcess anagen The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair. go-plus.json hair growth http://purl.obolibrary.org/obo/GO_0042640 gocheck_do_not_annotate UBERON:0007491 biolink:AnatomicalEntity chitin-based acellular structure Acellular anatomical structure whose predominant constituent is chitin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007491 UBERON:0007490 biolink:AnatomicalEntity keratin-based acellular structure Acellular anatomical structure whose predominant constituent is keratin. go-plus.json keratin-based structure http://purl.obolibrary.org/obo/UBERON_0007490 NCBITaxon:27254 biolink:OrganismalEntity Zosteraceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_27254 GO:0042642 biolink:CellularComponent actomyosin, myosin complex part The myosin part of any complex of actin, myosin, and accessory proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0042642 GO:0042641 biolink:CellularComponent actomyosin Any complex of actin, myosin, and accessory proteins. go-plus.json actomyosin structure|actomyosin complex http://purl.obolibrary.org/obo/GO_0042641 CHEBI:29651 biolink:ChemicalSubstance neoabietadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_29651 chebi_ph7_3 NCBITaxon:27257 biolink:OrganismalEntity Zostera go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_27257 CHEBI:29650 biolink:ChemicalSubstance narbonolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29650 chebi_ph7_3 GO:0042648 biolink:CellularComponent chloroplast chromosome A circular DNA molecule containing chloroplast encoded genes. go-plus.json http://purl.obolibrary.org/obo/GO_0042648 UBERON:0007499 biolink:AnatomicalEntity epithelial sac An epithelial tube that is open at one end only. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007499 GO:0042647 biolink:CellularComponent proplastid nucleoid The region of a proplastid to which the DNA is confined. go-plus.json http://purl.obolibrary.org/obo/GO_0042647 GO:0042649 biolink:CellularComponent prothylakoid Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light. go-plus.json http://purl.obolibrary.org/obo/GO_0042649 GO:0042644 biolink:CellularComponent chloroplast nucleoid The region of a chloroplast to which the DNA is confined. go-plus.json http://purl.obolibrary.org/obo/GO_0042644 GO:0042643 biolink:CellularComponent obsolete actomyosin, actin portion OBSOLETE. The actin part of any complex of actin, myosin, and accessory proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0042643 GO:0042646 biolink:CellularComponent plastid nucleoid The region of a plastid to which the DNA is confined. go-plus.json http://purl.obolibrary.org/obo/GO_0042646 GO:0042645 biolink:CellularComponent mitochondrial nucleoid The region of a mitochondrion to which the DNA is confined. go-plus.json http://purl.obolibrary.org/obo/GO_0042645 CHEBI:4075 biolink:ChemicalSubstance (R)-(1-aminoethyl)phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_4075 CHEBI:4077 biolink:ChemicalSubstance (4R,5S,6R)-2,4,5,6-tetrahydroxycyclohex-2-en-1-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_4077 chebi_ph7_3 CHEBI:30659 biolink:ChemicalSubstance D-thyroxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30659 CHEBI:30657 biolink:ChemicalSubstance D-homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_30657 NCBITaxon:91827 biolink:OrganismalEntity Gunneridae go-plus.json core eudicotyledons|core eudicots http://purl.obolibrary.org/obo/NCBITaxon_91827 CHEBI:30655 biolink:ChemicalSubstance L-homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_30655 CHEBI:4093 biolink:ChemicalSubstance D-allopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_4093 chebi_ph7_3 CHEBI:30654 biolink:ChemicalSubstance D-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30654 CHEBI:29669 biolink:ChemicalSubstance pyochelin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29669 GO:0042651 biolink:CellularComponent thylakoid membrane The pigmented membrane of any thylakoid. go-plus.json http://purl.obolibrary.org/obo/GO_0042651 GO:0042650 biolink:CellularComponent prothylakoid membrane The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0042650 GO:0042653 biolink:CellularComponent mitochondrial respiratory chain complex I, membrane segment The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. go-plus.json NADH-Q oxidoreductase complex, membrane segment http://purl.obolibrary.org/obo/GO_0042653 GO:0042652 biolink:CellularComponent mitochondrial respiratory chain complex I, peripheral segment The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. go-plus.json NADH-Q oxidoreductase complex, peripheral segment|NADH dehydrogenase (ubiquinone) complex, peripheral segment http://purl.obolibrary.org/obo/GO_0042652 CHEBI:29665 biolink:ChemicalSubstance pikromycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29665 GO:0042659 biolink:BiologicalProcess regulation of cell fate specification Any process that mediates the adoption of a specific fate by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0042659 GO:0042658 biolink:MolecularActivity MHC class II protein binding, via antigen binding groove Binding to the antigen binding groove of major histocompatibility complex class II molecules. go-plus.json major histocompatibility complex class II protein binding, via antigen binding groove http://purl.obolibrary.org/obo/GO_0042658 GO:0042655 biolink:BiologicalProcess obsolete activation of JNKKK activity OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase kinase (JNKKK) activity. go-plus.json activation of JUN kinase kinase kinase activity|positive regulation of JUNKKK activity http://purl.obolibrary.org/obo/GO_0042655 GO:0042654 biolink:MolecularActivity ecdysis-triggering hormone receptor activity Combining with ecdysis-triggering hormone to initiate a change in cell activity. go-plus.json ecdysis-triggering hormone binding|ETH receptor http://purl.obolibrary.org/obo/GO_0042654 GO:0042657 biolink:MolecularActivity MHC class II protein binding, via lateral surface Binding to the lateral surface of major histocompatibility complex class II molecules. go-plus.json major histocompatibility complex class II protein binding, via lateral surface http://purl.obolibrary.org/obo/GO_0042657 GO:0042656 biolink:MolecularActivity JUN kinase kinase kinase kinase activity Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs). go-plus.json JUNKKKK activity http://purl.obolibrary.org/obo/GO_0042656 CHEBI:30653 biolink:ChemicalSubstance homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30653 CHEBI:30624 biolink:ChemicalSubstance D-mannuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30624 chebi_ph7_3 CHEBI:30623 biolink:ChemicalSubstance oxalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30623 chebi_ph7_3 GO:0042662 biolink:BiologicalProcess negative regulation of mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification. go-plus.json down-regulation of mesodermal cell fate specification|suppression of mesodermal cell fate|downregulation of mesodermal cell fate specification|down regulation of mesodermal cell fate specification|inhibition of mesodermal cell fate specification http://purl.obolibrary.org/obo/GO_0042662 GO:0042661 biolink:BiologicalProcess regulation of mesodermal cell fate specification Any process that modulates the frequency, rate or extent of mesoderm cell fate specification. go-plus.json http://purl.obolibrary.org/obo/GO_0042661 CHEBI:29630 biolink:ChemicalSubstance methymycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29630 OBO:GOCHE_33232 biolink:OntologyClass substance with application role go-plus.json http://purl.obolibrary.org/obo/GOCHE_33232 3_STAR GO:0042664 biolink:BiologicalProcess negative regulation of endodermal cell fate specification Any process that restricts, stops or prevents a cell from specifying into an endoderm cell. go-plus.json down-regulation of endodermal cell fate specification|suppression of endodermal cell fate|downregulation of endodermal cell fate specification|negative regulation of endoderm cell fate specification|down regulation of endodermal cell fate specification|inhibition of endodermal cell fate specification|suppression of endoderm cell fate http://purl.obolibrary.org/obo/GO_0042664 GO:0042663 biolink:BiologicalProcess regulation of endodermal cell fate specification Any process that mediates the specification of a cell into an endoderm cell. go-plus.json regulation of endoderm cell fate specification http://purl.obolibrary.org/obo/GO_0042663 GO:0042660 biolink:BiologicalProcess positive regulation of cell fate specification Any process that activates or enables a cell to adopt a specific fate. go-plus.json up-regulation of cell fate specification|upregulation of cell fate specification|up regulation of cell fate specification|activation of cell fate specification|stimulation of cell fate specification http://purl.obolibrary.org/obo/GO_0042660 GO:0042669 biolink:BiologicalProcess regulation of inner ear auditory receptor cell fate specification Any process that mediates the specification of a cell into an auditory hair cell. go-plus.json regulation of inner ear auditory receptor cell fate specification|regulation of auditory hair cell fate specification http://purl.obolibrary.org/obo/GO_0042669 OBO:GOCHE_33229 biolink:OntologyClass substance with vitamin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_33229 3_STAR UBERON:0007475 biolink:AnatomicalEntity matrix-based tissue A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007475 GO:0042666 biolink:BiologicalProcess negative regulation of ectodermal cell fate specification Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell. go-plus.json down-regulation of ectodermal cell fate specification|suppression of ectodermal cell fate|downregulation of ectodermal cell fate specification|negative regulation of ectoderm cell fate specification|down regulation of ectodermal cell fate specification|inhibition of ectodermal cell fate specification|suppression of ectoderm cell fate http://purl.obolibrary.org/obo/GO_0042666 UBERON:0007473 biolink:AnatomicalEntity lumen of epithelial sac The space within an epithelial sphere. go-plus.json cavity of vesicle http://purl.obolibrary.org/obo/UBERON_0007473 GO:0042665 biolink:BiologicalProcess regulation of ectodermal cell fate specification Any process that mediates the specification of a cell into an ectoderm cell. go-plus.json regulation of ectoderm cell fate specification http://purl.obolibrary.org/obo/GO_0042665 GO:0042668 biolink:BiologicalProcess auditory receptor cell fate determination The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json auditory hair cell fate determination http://purl.obolibrary.org/obo/GO_0042668 GO:0042667 biolink:BiologicalProcess auditory receptor cell fate specification The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json auditory hair cell fate specification http://purl.obolibrary.org/obo/GO_0042667 CHEBI:30620 biolink:ChemicalSubstance (S)-2,3-dihydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30620 chebi_ph7_3 CHEBI:15022 biolink:ChemicalSubstance electron donor go-plus.json http://purl.obolibrary.org/obo/CHEBI_15022 CHEBI:4056 biolink:ChemicalSubstance cytochrome go-plus.json http://purl.obolibrary.org/obo/CHEBI_4056 NCBITaxon:7915 biolink:OrganismalEntity Lepisosteidae go-plus.json gars http://purl.obolibrary.org/obo/NCBITaxon_7915 NCBITaxon:7914 biolink:OrganismalEntity Semionotiformes go-plus.json Lepisosteiformes http://purl.obolibrary.org/obo/NCBITaxon_7914 CHEBI:29649 biolink:ChemicalSubstance narbomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29649 CHEBI:30633 biolink:ChemicalSubstance L-pipecolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30633 CHEBI:30632 biolink:ChemicalSubstance loganic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30632 GO:0042673 biolink:BiologicalProcess regulation of retinal cone cell fate specification Any process that mediates the specification of a cell into a retinal cone cell. go-plus.json http://purl.obolibrary.org/obo/GO_0042673 GO:0042672 biolink:BiologicalProcess retinal cone cell fate specification The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0042672 GO:0042675 biolink:BiologicalProcess compound eye cone cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye. go-plus.json http://purl.obolibrary.org/obo/GO_0042675 CL:1000746 biolink:Cell glomerular cell go-plus.json http://purl.obolibrary.org/obo/CL_1000746 GO:0042674 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042674 NCBITaxon:7918 biolink:OrganismalEntity Lepisosteus oculatus go-plus.json spotted gar http://purl.obolibrary.org/obo/NCBITaxon_7918 GO:0042671 biolink:BiologicalProcess retinal cone cell fate determination The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0042671 CL:1000742 biolink:Cell glomerular mesangial cell Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. go-plus.json intraglomerular mesangial cell http://purl.obolibrary.org/obo/CL_1000742 NCBITaxon:7916 biolink:OrganismalEntity Lepisosteus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_7916 GO:0042670 biolink:BiologicalProcess retinal cone cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. go-plus.json http://purl.obolibrary.org/obo/GO_0042670 GO:0042677 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042677 GO:0042676 biolink:BiologicalProcess compound eye cone cell fate commitment The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type. go-plus.json http://purl.obolibrary.org/obo/GO_0042676 GO:0042679 biolink:BiologicalProcess compound eye cone cell fate specification The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0042679 GO:0042678 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042678 GO:0052007 biolink:BiologicalProcess obsolete biosynthesis by symbiont of substance in host OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the formation of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json biosynthesis by organism of substance in host http://purl.obolibrary.org/obo/GO_0052007 CHEBI:30605 biolink:ChemicalSubstance disulfanyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30605 chebi_ph7_3 CHEBI:29616 biolink:ChemicalSubstance abieta-8(14),12-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_29616 chebi_ph7_3 GO:0052006 biolink:BiologicalProcess obsolete catabolism by symbiont of substance in host OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the breakdown of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of substance in host http://purl.obolibrary.org/obo/GO_0052006 GO:0052005 biolink:BiologicalProcess suppression by symbiont of host ethylene-mediated defense response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|inhibition by symbiont of host ethylene-mediated defense response|suppression by organism of host ethylene-mediated defense response|down regulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|downregulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|negative regulation by symbiont of host ethylene-mediated defense response|down-regulation by symbiont of host ethylene-mediated defense response http://purl.obolibrary.org/obo/GO_0052005 CHEBI:30604 biolink:ChemicalSubstance disulfanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30604 GO:0052004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052004 CHEBI:29613 biolink:ChemicalSubstance 3-O-(alpha-L-oleandrosyl)oleandolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29613 chebi_ph7_3 GO:0052009 biolink:BiologicalProcess disruption by symbiont of host cell wall A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json disassembly by symbiont of host cell wall http://purl.obolibrary.org/obo/GO_0052009 GO:0052008 biolink:BiologicalProcess disruption by symbiont of host cellular component The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism of host structural constituent by organism|disassembly by symbiont of host cellular component|degradation of host cellular component by organism|disassembly by organism of host cellular component|catabolism of host cellular component by organism http://purl.obolibrary.org/obo/GO_0052008 CHEBI:29614 biolink:ChemicalSubstance 3-O-(alpha-L-olivosyl)oleandolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29614 chebi_ph7_3 GO:0042684 biolink:BiologicalProcess cardioblast cell fate commitment The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0042684 GO:0042683 biolink:BiologicalProcess negative regulation of compound eye cone cell fate specification Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell. go-plus.json down-regulation of cone cell fate specification|suppression of cone cell fate|downregulation of cone cell fate specification|down regulation of cone cell fate specification|inhibition of cone cell fate specification http://purl.obolibrary.org/obo/GO_0042683 GO:0042686 biolink:BiologicalProcess regulation of cardioblast cell fate specification Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0042686 GO:0042685 biolink:BiologicalProcess cardioblast cell fate specification The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0042685 GO:0042680 biolink:BiologicalProcess compound eye cone cell fate determination The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0042680 GO:0042682 biolink:BiologicalProcess regulation of compound eye cone cell fate specification Any process that mediates the specification of a cell into a compound eye cone cell. go-plus.json http://purl.obolibrary.org/obo/GO_0042682 GO:0042681 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042681 GO:0042688 biolink:BiologicalProcess crystal cell differentiation The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. go-plus.json http://purl.obolibrary.org/obo/GO_0042688 GO:0042687 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042687 GO:0042689 biolink:BiologicalProcess regulation of crystal cell differentiation Any process that modulates the frequency, rate or extent of crystal cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0042689 GO:0052003 biolink:BiologicalProcess suppression by symbiont of defense-related host salicylic acid-mediated signal transduction pathway Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative modulation by organism of defense-related host salicylic acid-mediated signal transduction pathway|down regulation by symbiont of host salicylic acid-mediated defense response|downregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|negative regulation by organism of defense-related host SA-mediated signal transduction pathway|downregulation by symbiont of host salicylic acid-mediated defense response|down regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation of host SA-mediated defense response|inhibition by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|down-regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by organism of defense-related salicylic acid-mediated signal transduction pathway of other organism involved in symbiotic interaction|negative modulation by organism of defense-related host SA-mediated signal transduction pathway|inhibition by symbiont of host salicylic acid-mediated defense response|suppression by organism of host salicylic acid-mediated defense response|down-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|suppression of host SA mediated defense response http://purl.obolibrary.org/obo/GO_0052003 GO:0052002 biolink:BiologicalProcess obsolete metabolism by symbiont of substance in host OBSOLETE. The chemical reactions and pathways performed by an organism in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052002 GO:0052001 biolink:BiologicalProcess type IV pili-dependent localized adherence to host Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052001 GO:0052000 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052000 CHEBI:30617 biolink:ChemicalSubstance MgATP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30617 GO:0052018 biolink:BiologicalProcess modulation by symbiont of RNA levels in host The alteration by an organism of the levels of RNA in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host RNA levels http://purl.obolibrary.org/obo/GO_0052018 CHEBI:30616 biolink:ChemicalSubstance ATP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30616 chebi_ph7_3 GO:0052017 biolink:BiologicalProcess obsolete catabolism by symbiont of host xylan OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host xylan http://purl.obolibrary.org/obo/GO_0052017 GO:0052016 biolink:BiologicalProcess obsolete catabolism by symbiont of host glucan OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host glucan http://purl.obolibrary.org/obo/GO_0052016 GO:0052015 biolink:BiologicalProcess obsolete catabolism by symbiont of host carbohydrate OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host carbohydrate http://purl.obolibrary.org/obo/GO_0052015 CHEBI:30613 biolink:ChemicalSubstance glucarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30613 CHEBI:30612 biolink:ChemicalSubstance D-glucarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30612 chebi_ph7_3 GO:0052019 biolink:BiologicalProcess modulation by symbiont of host hormone or growth regulator levels The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052019 GO:0042695 biolink:BiologicalProcess thelarche The beginning of development of the breasts in the female. Wikipedia:Thelarche go-plus.json http://purl.obolibrary.org/obo/GO_0042695 GO:0042694 biolink:BiologicalProcess muscle cell fate specification The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0042694 GO:0042697 biolink:BiologicalProcess menopause Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. Wikipedia:Menopause go-plus.json http://purl.obolibrary.org/obo/GO_0042697 gocheck_do_not_annotate GO:0042696 biolink:BiologicalProcess menarche The beginning of the menstrual cycle; the first menstrual cycle in an individual. Wikipedia:Menarche go-plus.json http://purl.obolibrary.org/obo/GO_0042696 gocheck_do_not_annotate GO:0042691 biolink:BiologicalProcess positive regulation of crystal cell differentiation Any process that activates or increases the frequency, rate or extent of crystal cell differentiation. go-plus.json up regulation of crystal cell differentiation|upregulation of crystal cell differentiation|stimulation of crystal cell differentiation|up-regulation of crystal cell differentiation|activation of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042691 GO:0042690 biolink:BiologicalProcess negative regulation of crystal cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation. go-plus.json down-regulation of crystal cell differentiation|downregulation of crystal cell differentiation|down regulation of crystal cell differentiation|inhibition of crystal cell differentiation http://purl.obolibrary.org/obo/GO_0042690 CHEBI:30619 biolink:ChemicalSubstance 2,4-divinyl protochlorophyllide a go-plus.json http://purl.obolibrary.org/obo/CHEBI_30619 GO:0042693 biolink:BiologicalProcess muscle cell fate commitment The process in which the cellular identity of muscle cells is acquired and determined. go-plus.json http://purl.obolibrary.org/obo/GO_0042693 GO:0042692 biolink:BiologicalProcess muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. go-plus.json myogenesis http://purl.obolibrary.org/obo/GO_0042692 GO:0042699 biolink:BiologicalProcess follicle-stimulating hormone signaling pathway The series of molecular signals mediated by follicle-stimulating hormone. go-plus.json follicle stimulating hormone signaling pathway|follicle stimulating hormone signalling pathway|follicle-stimulating hormone signalling pathway http://purl.obolibrary.org/obo/GO_0042699 GO:0042698 biolink:BiologicalProcess ovulation cycle The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. go-plus.json http://purl.obolibrary.org/obo/GO_0042698 GO:0052010 biolink:BiologicalProcess obsolete catabolism by symbiont of host cell wall cellulose OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host cell wall cellulose http://purl.obolibrary.org/obo/GO_0052010 GO:0052014 biolink:BiologicalProcess obsolete catabolism by symbiont of host protein OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host protein http://purl.obolibrary.org/obo/GO_0052014 GO:0052013 biolink:BiologicalProcess obsolete catabolism by symbiont of host macromolecule OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host macromolecule http://purl.obolibrary.org/obo/GO_0052013 GO:0052012 biolink:BiologicalProcess obsolete catabolism by symbiont of host cell wall chitin OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host cell wall chitin http://purl.obolibrary.org/obo/GO_0052012 GO:0052011 biolink:BiologicalProcess obsolete catabolism by symbiont of host cell wall pectin OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json catabolism by organism of host cell wall pectin http://purl.obolibrary.org/obo/GO_0052011 GO:0052029 biolink:BiologicalProcess suppression by symbiont of host signal transduction pathway Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host signal transduction pathway|down-regulation by symbiont of host signal transduction pathway|negative modulation by organism of host signal transduction pathway|downregulation by symbiont of host signal transduction pathway|negative regulation by organism of signal transduction in other organism involved in symbiotic interaction|down regulation by symbiont of host signal transduction pathway|inhibition by symbiont of host signal transduction pathway http://purl.obolibrary.org/obo/GO_0052029 GO:0052028 biolink:BiologicalProcess induction by symbiont of host signal transduction pathway Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host signal transduction pathway|up regulation by symbiont of host signal transduction pathway|positive regulation by organism of signal transduction in other organism involved in symbiotic interaction|positive regulation of signal transduction in other organism|upregulation by symbiont of host signal transduction pathway|stimulation by symbiont of host signal transduction pathway|up-regulation by symbiont of host signal transduction pathway|activation by symbiont of host signal transduction pathway http://purl.obolibrary.org/obo/GO_0052028 GO:0052027 biolink:BiologicalProcess modulation by symbiont of host signal transduction pathway Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of host signal transduction by symbiont|modulation by symbiont of host signal transduction|regulation by symbiont of host signal transduction pathway|modulation of signal transduction in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052027 GO:0052026 biolink:BiologicalProcess modulation by symbiont of host transcription Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052026 GO:0052021 biolink:BiologicalProcess modulation by symbiont of ethylene levels in host The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of ethylene levels in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052021 GO:0052020 biolink:BiologicalProcess modification by symbiont of host cell wall The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json metabolism of host cell wall by organism http://purl.obolibrary.org/obo/GO_0052020 GO:0052025 biolink:BiologicalProcess modification by symbiont of host cell membrane The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification by symbiont of host cell membrane http://purl.obolibrary.org/obo/GO_0052025 GO:0052024 biolink:BiologicalProcess positive regulation by symbiont of hormone or growth regulator levels in host The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive modulation of hormone or growth regulator levels in host|up regulation by symbiont of hormone or growth regulator levels in host|positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction|upregulation by symbiont of hormone or growth regulator levels in host|stimulation by symbiont of hormone or growth regulator levels in host|up-regulation by symbiont of hormone or growth regulator levels in host|activation by symbiont of hormone or growth regulator levels in host http://purl.obolibrary.org/obo/GO_0052024 GO:0052023 biolink:BiologicalProcess modulation by symbiont of salicylic acid levels in host The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of salicylic acid levels in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052023 GO:0052022 biolink:BiologicalProcess modulation by symbiont of jasmonic acid levels in host The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of jasmonic acid levels in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052022 GO:0052039 biolink:BiologicalProcess disruption by symbiont of host cytoskeleton The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modification by symbiont of host cytoskeleton|rounding by symbiont of host cells http://purl.obolibrary.org/obo/GO_0052039 CHEBI:29605 biolink:ChemicalSubstance gibberellin A9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_29605 GO:0052038 biolink:BiologicalProcess modulation by symbiont of host intracellular transport Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of host intracellular trafficking http://purl.obolibrary.org/obo/GO_0052038 GO:0052037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052037 NCBITaxon:7955 biolink:OrganismalEntity Danio rerio go-plus.json Brachydanio rerio frankei|Danio frankei|zebrafish|zebra danio|Cyprinus rerio|Brachydanio rerio|zebra fish|leopard danio|Danio rerio frankei http://purl.obolibrary.org/obo/NCBITaxon_7955 NCBITaxon:7954 biolink:OrganismalEntity Danio go-plus.json Celestichthys|Brachydanio http://purl.obolibrary.org/obo/NCBITaxon_7954 NCBITaxon:7952 biolink:OrganismalEntity Cypriniformes go-plus.json carps and others http://purl.obolibrary.org/obo/NCBITaxon_7952 CL:1000706 biolink:Cell ureter urothelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000706 GO:0052032 biolink:BiologicalProcess modulation by symbiont of host inflammatory response Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of inflammatory response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052032 GO:0052031 biolink:BiologicalProcess modulation by symbiont of host defense response Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json mitigation by symbiont of host defense response|modulation by organism of defense response of other organism involved in symbiotic interaction|pathogenesis http://purl.obolibrary.org/obo/GO_0052031 GO:0052030 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052030 GO:0052036 biolink:BiologicalProcess suppression by symbiont of host inflammatory response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json downregulation by symbiont of host inflammatory response|down regulation by symbiont of host inflammatory response|inhibition by symbiont of host inflammatory response|negative regulation by organism of inflammatory response of other organism involved in symbiotic interaction|down-regulation by symbiont of host inflammatory response|negative regulation by symbiont of host inflammatory response http://purl.obolibrary.org/obo/GO_0052036 GO:0052035 biolink:BiologicalProcess positive regulation by symbiont of host inflammatory response Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json up regulation by symbiont of host inflammatory response|positive regulation by organism of inflammatory response of other organism involved in symbiotic interaction|upregulation by symbiont of host inflammatory response|stimulation by symbiont of host inflammatory response|up-regulation by symbiont of host inflammatory response|activation by symbiont of host inflammatory response http://purl.obolibrary.org/obo/GO_0052035 GO:0052034 biolink:BiologicalProcess effector-mediated suppression of host pattern-triggered immunity A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json suppression of general elicitor-induced host innate immunity|downregulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|down regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of general elicitor induced host innate immunity|suppression of PAMP-induced host innate immunity|suppression of pathogen-associated molecular pattern-induced host innate immunity|suppression of MAMP-induced host innate immunity|inhibition by symbiont of pathogen-associated molecular pattern-induced host innate immunity|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immune response|negative regulation by organism of pathogen-associated molecular pattern-induced innate immune response of other organism involved in symbiotic interaction|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|suppression by symbiont of microbe-associated molecular pattern-induced host innate immune response|suppression of PAMP induced host innate immunity|down-regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of MAMP induced host innate immunity http://purl.obolibrary.org/obo/GO_0052034 GO:0052033 biolink:BiologicalProcess obsolete pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json pathogen-associated molecular pattern dependent activation by organism of host innate immunity|PAMP dependent activation of host innate immunity|MAMP dependent activation of host innate immunity|pattern-triggered immunity|general elicitor-dependent activation of host innate immunity|general elicitor-dependent induction of host innate immunity|pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity|MAMP dependent induction of host innate immunity|PAMP dependent induction of host innate immunity|PTI http://purl.obolibrary.org/obo/GO_0052033 CHEBI:78548 biolink:ChemicalSubstance adenylate cyclase agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_78548 UBERON:0007530 biolink:AnatomicalEntity migrating mesenchyme population Mesenchymal cells that are migrating. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007530 CHEBI:78542 biolink:ChemicalSubstance beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78542 chebi_ph7_3 CHEBI:78541 biolink:ChemicalSubstance 1-hexadecyl-2-amino-2-deoxy-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78541 CHEBI:78547 biolink:ChemicalSubstance protein kinase A agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_78547 CHEBI:78559 biolink:ChemicalSubstance (2S,3S)-3-hydroxy-2-methylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78559 chebi_ph7_3 UBERON:0007521 biolink:AnatomicalEntity smooth muscle sphincter A ring of smooth muscle cells whose contraction closes the opening of the ring. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007521 CHEBI:136731 biolink:ChemicalSubstance 5-hydroxymethyldeoxycytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136731 chebi_ph7_3 CHEBI:136730 biolink:ChemicalSubstance (S)-all-trans-4-hydroxyretinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136730 CHEBI:136735 biolink:ChemicalSubstance (R)-tetrahydropapaverine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136735 CHEBI:136734 biolink:ChemicalSubstance (R)-laudanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136734 UBERON:0007529 biolink:AnatomicalEntity loose mesenchyme tissue Mesenchyme whose cells are embedded in obvious amounts of extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007529 CHEBI:78554 biolink:ChemicalSubstance 2-methyl-3-hydroxybutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78554 chebi_ph7_3 CHEBI:78552 biolink:ChemicalSubstance ribonucleoside 2'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78552 chebi_ph7_3 CHEBI:78551 biolink:ChemicalSubstance 3'-(O-phosphonato-L-seryl)adenylyl(2-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78551 chebi_ph7_3 UBERON:0007524 biolink:AnatomicalEntity dense mesenchyme tissue Mesenchyme with little extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007524 CHEBI:78556 biolink:ChemicalSubstance 3'-(L-pyrrolysyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78556 chebi_ph7_3 UBERON:0007522 biolink:AnatomicalEntity striated muscle sphincter A ring of striated muscle cells whose contraction closes the opening of the ring. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007522 CHEBI:136708 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phosphonato-alpha-D-mannosyl-L-serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136708 chebi_ph7_3 CHEBI:136707 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136707 chebi_ph7_3 CHEBI:29593 biolink:ChemicalSubstance gibberellin A34 go-plus.json http://purl.obolibrary.org/obo/CHEBI_29593 CHEBI:136709 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136709 chebi_ph7_3 CHEBI:136700 biolink:ChemicalSubstance 3-oxocholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136700 chebi_ph7_3 CHEBI:136704 biolink:ChemicalSubstance N-propanoyl-L-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136704 chebi_ph7_3 PR:000006933 biolink:Protein epidermal growth factor receptor An EGF receptor type tyrosine-protein kinase that is a translation product of the human EGFR gene or a 1:1 ortholog thereof. go-plus.json receptor tyrosine-protein kinase erbB-1|proto-oncogene c-ErbB-1|EGFR|ERBB1 http://purl.obolibrary.org/obo/PR_000006933 CHEBI:136703 biolink:ChemicalSubstance 3-oxocholan-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136703 chebi_ph7_3 CHEBI:136702 biolink:ChemicalSubstance ximelagatran (hydroxylamine form) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136702 CHEBI:136701 biolink:ChemicalSubstance 3-oxodeoxycholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136701 chebi_ph7_3 NCBITaxon:91882 biolink:OrganismalEntity campanulids go-plus.json euasterids II http://purl.obolibrary.org/obo/NCBITaxon_91882 CHEBI:78565 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)- beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_78565 chebi_ph7_3 CHEBI:30585 biolink:ChemicalSubstance silicide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30585 CHEBI:30584 biolink:ChemicalSubstance silicon(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30584 chebi_ph7_3 CHEBI:78569 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78569 chebi_ph7_3 CHEBI:78568 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78568 chebi_ph7_3 NCBITaxon:91888 biolink:OrganismalEntity lamiids go-plus.json euasterids I http://purl.obolibrary.org/obo/NCBITaxon_91888 CHEBI:78566 biolink:ChemicalSubstance 1-(1Z)-alkenyl-2-acetyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78566 chebi_ph7_3 CHEBI:136717 biolink:ChemicalSubstance C-terminal-gamma-(5-phospho-L-glutamyl )-L-glutamyl(4-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136717 chebi_ph7_3 CHEBI:136716 biolink:ChemicalSubstance N-(fatty acyl)-L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136716 chebi_ph7_3 CHEBI:136711 biolink:ChemicalSubstance N-oleoyl-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136711 CHEBI:136710 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phosphonato-alpha-D-mannosyl-L-threonine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136710 chebi_ph7_3 CHEBI:78572 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78572 chebi_ph7_3 CHEBI:136714 biolink:ChemicalSubstance C-terminal-gamma-(L-glutamyl)-L-glutamyl(3-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136714 chebi_ph7_3 CHEBI:78571 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78571 chebi_ph7_3 CHEBI:136713 biolink:ChemicalSubstance N-oleoyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136713 CHEBI:136712 biolink:ChemicalSubstance pivaloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136712 chebi_ph7_3 CHEBI:78574 biolink:ChemicalSubstance pyrimidinecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78574 CHEBI:78573 biolink:ChemicalSubstance 3'-(L-selenocysteinyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78573 chebi_ph7_3 UBERON:0007503 biolink:AnatomicalEntity epithelial vesicle A closed epithelium with a lumen. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007503 UBERON:0007501 biolink:AnatomicalEntity arborizing epithelial duct system A collection of connected epithelial tubes with a single portal. go-plus.json arborising epithelial duct system http://purl.obolibrary.org/obo/UBERON_0007501 UBERON:0007500 biolink:AnatomicalEntity epithelial tube open at both ends An epithelial tube open at both ends that allows fluid flow. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007500 CHEBI:29579 biolink:ChemicalSubstance epothilone D go-plus.json http://purl.obolibrary.org/obo/CHEBI_29579 chebi_ph7_3 CHEBI:30566 biolink:ChemicalSubstance gamma-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30566 CHEBI:29572 biolink:ChemicalSubstance demethyllactenocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29572 CHEBI:29571 biolink:ChemicalSubstance dehydroabietic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29571 GO:0042604 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042604 GO:0042603 biolink:CellularComponent capsule A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication. Wikipedia:Capsule_(microbiology) go-plus.json http://purl.obolibrary.org/obo/GO_0042603 GO:0042606 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042606 GO:0042605 biolink:MolecularActivity peptide antigen binding Binding to an antigen peptide. go-plus.json exogenous peptide antigen binding|endogenous peptide antigen binding http://purl.obolibrary.org/obo/GO_0042605 goslim_chembl GO:0042600 biolink:CellularComponent egg chorion A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish. go-plus.json http://purl.obolibrary.org/obo/GO_0042600 goslim_pir GO:0042602 biolink:MolecularActivity riboflavin reductase (NADPH) activity Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+. KEGG_REACTION:R05707|EC:1.5.1.41|EC:1.5.1.30|MetaCyc:NADPH-DEHYDROGENASE-FLAVIN-RXN|RHEA:19377 go-plus.json NADPH-specific FMN reductase activity|NADPH2:riboflavin oxidoreductase activity|NADPH:riboflavin oxidoreductase activity|flavin reductase activity|NADPH-dependent FMN reductase activity|NADPH-FMN reductase activity|NADPH dehydrogenase (riboflavin) activity|NADPH-riboflavin reductase activity|NADPH-riboflavin oxidoreductase activity|FMN reductase (NADPH) activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADPH2 dehydrogenase (riboflavin)|reduced-riboflavin:NADP+ oxidoreductase activity|riboflavin mononucleotide reductase activity|riboflavine mononucleotide reductase activity http://purl.obolibrary.org/obo/GO_0042602 GO:0042601 biolink:CellularComponent endospore-forming forespore Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0042601 CHEBI:30563 biolink:ChemicalSubstance silicon dioxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30563 chebi_ph7_3 GO:0042608 biolink:MolecularActivity T cell receptor binding Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells. go-plus.json T lymphocyte receptor binding|T-lymphocyte receptor binding|TCR binding|T-cell receptor binding http://purl.obolibrary.org/obo/GO_0042608 GO:0042607 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042607 CHEBI:78589 biolink:ChemicalSubstance 2-O,3-dimethylflaviolin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78589 chebi_ph7_3 GO:0042609 biolink:MolecularActivity CD4 receptor binding Binding to a CD4, a receptor found on the surface of T cells, monocytes and macrophages. go-plus.json http://purl.obolibrary.org/obo/GO_0042609 CHEBI:78588 biolink:ChemicalSubstance 6-linalyl-2-O,3-dimethylflaviolin-7-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78588 chebi_ph7_3 CHEBI:78590 biolink:ChemicalSubstance 7-O-geranyl-2-O,3-dimethylflaviolin go-plus.json http://purl.obolibrary.org/obo/CHEBI_78590 chebi_ph7_3 GO:0042615 biolink:MolecularActivity CD154 receptor binding Binding to CD154, a receptor found on the surface of some activated lymphocytes. go-plus.json CD40L binding|CD40 receptor activity http://purl.obolibrary.org/obo/GO_0042615 GO:0042614 biolink:MolecularActivity CD70 receptor binding Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells. go-plus.json CD27 receptor activity|CD27L binding http://purl.obolibrary.org/obo/GO_0042614 GO:0042617 biolink:BiologicalProcess paclitaxel biosynthetic process The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. go-plus.json paclitaxel anabolism|paclitaxel synthesis|paclitaxel formation|taxol biosynthetic process|taxol biosynthesis|paclitaxel biosynthesis http://purl.obolibrary.org/obo/GO_0042617 GO:0042616 biolink:BiologicalProcess paclitaxel metabolic process The chemical reactions and pathways involving paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. go-plus.json taxol metabolic process|taxol metabolism|paclitaxel metabolism http://purl.obolibrary.org/obo/GO_0042616 CHEBI:78594 biolink:ChemicalSubstance 5alpha-pregan-20beta-ol-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_78594 chebi_ph7_3 GO:0042611 biolink:CellularComponent MHC protein complex A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen. go-plus.json http://purl.obolibrary.org/obo/GO_0042611 goslim_pir GO:0042610 biolink:MolecularActivity CD8 receptor binding Binding to a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes. go-plus.json http://purl.obolibrary.org/obo/GO_0042610 GO:0042613 biolink:CellularComponent MHC class II protein complex A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen. go-plus.json http://purl.obolibrary.org/obo/GO_0042613 GO:0042612 biolink:CellularComponent MHC class I protein complex A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0042612 CHEBI:78598 biolink:ChemicalSubstance N-acetylamino-acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78598 chebi_ph7_3 CHEBI:78597 biolink:ChemicalSubstance N-terminal alpha-amino-acid(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78597 chebi_ph7_3 CHEBI:78596 biolink:ChemicalSubstance 21-dehydrocortisone go-plus.json http://purl.obolibrary.org/obo/CHEBI_78596 chebi_ph7_3 CHEBI:78595 biolink:ChemicalSubstance 21-dehydrocortisol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78595 chebi_ph7_3 GO:0042619 biolink:BiologicalProcess poly-hydroxybutyrate biosynthetic process The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells. go-plus.json poly-hydroxybutyrate biosynthesis|PHB biosynthesis|PHB biosynthetic process|poly-hydroxybutyrate anabolism|poly-hydroxybutyrate synthesis|poly-hydroxybutyrate formation http://purl.obolibrary.org/obo/GO_0042619 GO:0042618 biolink:BiologicalProcess poly-hydroxybutyrate metabolic process The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells. go-plus.json poly-hydroxybutyrate metabolism|PHB metabolism|PHB metabolic process http://purl.obolibrary.org/obo/GO_0042618 UBERON:0007567 biolink:AnatomicalEntity regenerating anatomical structure An anatomical structure that is undergoing regeneration. go-plus.json regenerative tissue|regenerating tissue|regenerating tissues http://purl.obolibrary.org/obo/UBERON_0007567 CHEBI:78599 biolink:ChemicalSubstance (gamma-L-glutamyl) N-terminal alpha-amino-acid zwitterionic residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78599 chebi_ph7_3 NCBITaxon:91835 biolink:OrganismalEntity fabids go-plus.json eurosids I http://purl.obolibrary.org/obo/NCBITaxon_91835 NCBITaxon:91834 biolink:OrganismalEntity rosids incertae sedis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_91834 PR:000016301 biolink:Protein tyrosine 3-monooxygenase A protein that is a translation product of the human TH gene or a 1:1 ortholog thereof. go-plus.json tyrosine 3-hydroxylase|TYH|TH http://purl.obolibrary.org/obo/PR_000016301 NCBITaxon:91836 biolink:OrganismalEntity malvids go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_91836 GO:0042620 biolink:BiologicalProcess poly(3-hydroxyalkanoate) metabolic process The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. go-plus.json PHA metabolic process|PHA metabolism|poly(3-hydroxyalkanoate) metabolism http://purl.obolibrary.org/obo/GO_0042620 goslim_pir CHEBI:29556 biolink:ChemicalSubstance chloroeremomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29556 GO:0042626 biolink:MolecularActivity ATPase-coupled transmembrane transporter activity Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. Reactome:R-HSA-2161506|Reactome:R-HSA-2161538|Reactome:R-HSA-1467457|Reactome:R-HSA-9033505|Reactome:R-HSA-9033499 go-plus.json P-P-bond-hydrolysis-driven transmembrane transporter activity|ATP-dependent transmembrane transporter activity|P-P-bond-hydrolysis-driven transporter|ATPase activity, coupled to movement of substances|ATP-coupled transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances http://purl.obolibrary.org/obo/GO_0042626 GO:0042625 biolink:MolecularActivity ATPase-coupled ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate. go-plus.json ATP-dependent ion transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of ions|ATPase coupled ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0042625 GO:0042628 biolink:BiologicalProcess mating plug formation The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males. go-plus.json copulatory plug biosynthesis|copulatory plug deposition|mating plug deposition|copulatory plug formation http://purl.obolibrary.org/obo/GO_0042628 GO:0042627 biolink:CellularComponent chylomicron A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues. Wikipedia:Chylomicron go-plus.json http://purl.obolibrary.org/obo/GO_0042627 GO:0042622 biolink:CellularComponent photoreceptor outer segment membrane The membrane surrounding the outer segment of a vertebrate photoreceptor. go-plus.json http://purl.obolibrary.org/obo/GO_0042622 GO:0042621 biolink:BiologicalProcess poly(3-hydroxyalkanoate) biosynthetic process The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. go-plus.json poly(3-hydroxyalkanoate) anabolism|poly(3-hydroxyalkanoate) synthesis|poly(3-hydroxyalkanoate) formation|PHA biosynthesis|poly(3-hydroxyalkanoate) biosynthesis|PHA biosynthetic process http://purl.obolibrary.org/obo/GO_0042621 GO:0042624 biolink:MolecularActivity obsolete ATPase activity, uncoupled OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0042624 GO:0042623 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042623 GO:0042629 biolink:CellularComponent mast cell granule Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase. go-plus.json http://purl.obolibrary.org/obo/GO_0042629 GO:0042631 biolink:BiologicalProcess cellular response to water deprivation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water. go-plus.json cellular response to drought http://purl.obolibrary.org/obo/GO_0042631 GO:0042630 biolink:BiologicalProcess behavioral response to water deprivation Any process that results in a change in the behavior of an organism as a result of deprivation of water. go-plus.json behavioural response to water deprivation|behavioral response to drought|behavioral response to thirst http://purl.obolibrary.org/obo/GO_0042630 PR:000006990 biolink:Protein eukaryotic translation initiation factor 4E A protein that is a translation product of the human EIF4E gene or a 1:1 ortholog thereof. go-plus.json mRNA cap-binding protein|eIF-4E|EIF4E|eIF4E|EIF4EL1|eIF-4F 25 kDa subunit|EIF4F http://purl.obolibrary.org/obo/PR_000006990 GO:0042637 biolink:BiologicalProcess catagen The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced. go-plus.json hair regression http://purl.obolibrary.org/obo/GO_0042637 gocheck_do_not_annotate GO:0042636 biolink:BiologicalProcess negative regulation of hair cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. go-plus.json downregulation of hair cycle|down regulation of hair cycle|inhibition of hair cycle|down-regulation of hair cycle http://purl.obolibrary.org/obo/GO_0042636 GO:0042639 biolink:BiologicalProcess telogen The resting phase of hair cycle. go-plus.json hair resting phase http://purl.obolibrary.org/obo/GO_0042639 gocheck_do_not_annotate GO:0042638 biolink:BiologicalProcess exogen The shedding phase of the hair cycle. go-plus.json hair shedding http://purl.obolibrary.org/obo/GO_0042638 gocheck_do_not_annotate GO:0042633 biolink:BiologicalProcess hair cycle The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0042633 GO:0042632 biolink:BiologicalProcess cholesterol homeostasis Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell. go-plus.json positive regulation of cholesterol homeostasis|regulation of cholesterol homeostasis http://purl.obolibrary.org/obo/GO_0042632 GO:0042635 biolink:BiologicalProcess positive regulation of hair cycle Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. go-plus.json up regulation of hair cycle|upregulation of hair cycle|stimulation of hair cycle|up-regulation of hair cycle|activation of hair cycle http://purl.obolibrary.org/obo/GO_0042635 GO:0042634 biolink:BiologicalProcess regulation of hair cycle Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. go-plus.json http://purl.obolibrary.org/obo/GO_0042634 GO:0003039 biolink:BiologicalProcess detection of reduced oxygen by carotid body chemoreceptor signaling The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body. go-plus.json detection of reduced oxygen by carotid body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003039 GO:0003036 biolink:BiologicalProcess detection of pH by aortic body chemoreceptor signaling The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body. go-plus.json detection of pH by aortic body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003036 GO:0003035 biolink:BiologicalProcess detection of increased carbon dioxide by carotid body chemoreceptor signaling The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body. go-plus.json detection of increased carbon dioxide by carotid body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003035 GO:0003038 biolink:BiologicalProcess detection of reduced oxygen by aortic body chemoreceptor signaling The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body. go-plus.json detection of reduced oxygen by aortic body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003038 GO:0003037 biolink:BiologicalProcess detection of pH by carotid body chemoreceptor signaling The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body. go-plus.json detection of pH by carotid body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003037 GO:0003032 biolink:BiologicalProcess detection of oxygen The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0003032 GO:0003031 biolink:BiologicalProcess detection of carbon dioxide The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0003031 GO:0003034 biolink:BiologicalProcess detection of increased carbon dioxide by aortic body chemoreceptor signaling The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body. go-plus.json detection of increased carbon dioxide by aortic body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003034 GO:0003033 biolink:BiologicalProcess detection of hypoxic conditions in blood by aortic body chemoreceptor signaling The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies. go-plus.json detection of hypoxic conditions in blood by aortic body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003033 NCBITaxon:976 biolink:OrganismalEntity Bacteroidetes go-plus.json Bacteroidaeota|BCF group|Cytophaga-Flexibacter-Bacteroides phylum|Bacteroides-Cytophaga-Flexibacter group|CFB group|CFB group bacteria|Bacteroidota http://purl.obolibrary.org/obo/NCBITaxon_976 GO:0003030 biolink:BiologicalProcess detection of hydrogen ion The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0003030 GO:0003047 biolink:BiologicalProcess regulation of systemic arterial blood pressure by epinephrine The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine. go-plus.json blood pressure regulation by epinephrine|regulation of blood pressure by adrenaline http://purl.obolibrary.org/obo/GO_0003047 GO:0003046 biolink:BiologicalProcess regulation of systemic arterial blood pressure by stress relaxation The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs. go-plus.json blood pressure regulation by stress relaxation http://purl.obolibrary.org/obo/GO_0003046 GO:0003049 biolink:BiologicalProcess regulation of systemic arterial blood pressure by capillary fluid shift The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment. go-plus.json blood pressure regulation by capillary fluid shift http://purl.obolibrary.org/obo/GO_0003049 GO:0003048 biolink:BiologicalProcess regulation of systemic arterial blood pressure by norepinephrine The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine. go-plus.json blood pressure regulation by norepinephrine|regulation of blood pressure by noradrenaline http://purl.obolibrary.org/obo/GO_0003048 GO:0003043 biolink:BiologicalProcess vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure. go-plus.json vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003043 GO:0003042 biolink:BiologicalProcess vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure. go-plus.json vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003042 GO:0003045 biolink:BiologicalProcess regulation of systemic arterial blood pressure by physical factors The regulation of blood pressure mediated by detection of forces within the circulatory system. go-plus.json blood pressure regulation by physical factors http://purl.obolibrary.org/obo/GO_0003045 GO:0003044 biolink:BiologicalProcess regulation of systemic arterial blood pressure mediated by a chemical signal The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. go-plus.json blood pressure regulation mediated by a chemical signal http://purl.obolibrary.org/obo/GO_0003044 GO:0003041 biolink:BiologicalProcess excitation of vasomotor center by carotid body chemoreceptor signaling The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure. go-plus.json excitation of vasomotor center by carotid body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003041 GO:0003040 biolink:BiologicalProcess excitation of vasomotor center by aortic body chemoreceptor signaling The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure. go-plus.json excitation of vasomotor center by aortic body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003040 GO:0003018 biolink:BiologicalProcess vascular process in circulatory system A circulatory process that occurs at the level of the vasculature. go-plus.json vasculature process http://purl.obolibrary.org/obo/GO_0003018 GO:0003017 biolink:BiologicalProcess lymph circulation The flow of lymph through the body of an animal. go-plus.json http://purl.obolibrary.org/obo/GO_0003017 GO:0003019 biolink:BiologicalProcess central nervous system control of baroreceptor feedback The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris. go-plus.json http://purl.obolibrary.org/obo/GO_0003019 GO:0003014 biolink:BiologicalProcess renal system process A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). go-plus.json kidney system process|excretory system process http://purl.obolibrary.org/obo/GO_0003014 GO:0003013 biolink:BiologicalProcess circulatory system process A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. Wikipedia:Circulatory_system go-plus.json http://purl.obolibrary.org/obo/GO_0003013 goslim_generic|goslim_chembl GO:0003016 biolink:BiologicalProcess respiratory system process A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. go-plus.json respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0003016 GO:0003015 biolink:BiologicalProcess heart process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. go-plus.json cardiac process http://purl.obolibrary.org/obo/GO_0003015 GO:0003010 biolink:BiologicalProcess voluntary skeletal muscle contraction A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control. go-plus.json http://purl.obolibrary.org/obo/GO_0003010 GO:0003012 biolink:BiologicalProcess muscle system process A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. go-plus.json muscle physiological process http://purl.obolibrary.org/obo/GO_0003012 GO:0003011 biolink:BiologicalProcess involuntary skeletal muscle contraction A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control. go-plus.json http://purl.obolibrary.org/obo/GO_0003011 GO:0003029 biolink:BiologicalProcess detection of hypoxic conditions in blood by carotid body chemoreceptor signaling The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies. go-plus.json detection of hypoxic conditions in blood by carotid body chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003029 GO:0003028 biolink:BiologicalProcess regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. go-plus.json aortic body chemoreceptor regulation of systemic arterial blood pressure|regulation of systemic arterial blood pressure by aortic body chemoreceptor signalling|aortic body chemoreceptor response to lowering of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003028 GO:0003025 biolink:BiologicalProcess regulation of systemic arterial blood pressure by baroreceptor feedback The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control. go-plus.json baroreceptor regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003025 GO:0003024 biolink:BiologicalProcess baroreceptor detection of decreased arterial stretch The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0003024 GO:0003027 biolink:BiologicalProcess regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. go-plus.json carotid body chemoreceptor response to lowering of systemic arterial blood pressure|regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling|carotid body chemoreceptor regulation of systemic arterial blood pressure|vagal reflex http://purl.obolibrary.org/obo/GO_0003027 GO:0003026 biolink:BiologicalProcess regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control. go-plus.json aortic arch baroreceptor control of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0003026 GO:0003021 biolink:BiologicalProcess detection of increased carbon dioxide by chemoreceptor signaling The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. go-plus.json detection of increased carbon dioxide by chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003021 GO:0003020 biolink:BiologicalProcess detection of reduced oxygen by chemoreceptor signaling The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. go-plus.json detection of reduced oxygen by chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003020 GO:0003023 biolink:BiologicalProcess baroreceptor detection of increased arterial stretch The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0003023 GO:0003022 biolink:BiologicalProcess detection of pH by chemoreceptor signaling The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors. go-plus.json detection of pH by chemoreceptor signalling http://purl.obolibrary.org/obo/GO_0003022 CHEBI:136799 biolink:ChemicalSubstance 5-methyl-2-thiouridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136799 chebi_ph7_3 CHEBI:136798 biolink:ChemicalSubstance 4-thiouridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136798 chebi_ph7_3 CHEBI:136766 biolink:ChemicalSubstance N-acetyl-L-alpha-phenylglycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136766 chebi_ph7_3 CHEBI:136765 biolink:ChemicalSubstance L-alpha-phenylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136765 chebi_ph7_3 CHEBI:136763 biolink:ChemicalSubstance C-terminal-gamma-(L-ornithyl)-L-glutamyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136763 chebi_ph7_3 CHEBI:136769 biolink:ChemicalSubstance alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl-(1->3)-1,2-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136769 chebi_ph7_3 CHEBI:78503 biolink:ChemicalSubstance C-terminal-gamma-L-glutamyl-L-2-aminoadipate(3-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78503 chebi_ph7_3 CHEBI:136761 biolink:ChemicalSubstance C-terminal-gamma-(L-glutamyl 5-semialdehyde)-L-glutamyl(2-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136761 chebi_ph7_3 CHEBI:78502 biolink:ChemicalSubstance (S)-2-aminopropan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78502 CHEBI:136760 biolink:ChemicalSubstance short-chain (3S)-hydroxy fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136760 chebi_ph7_3 CHEBI:78501 biolink:ChemicalSubstance C-terminal-gamma-L-glutamyl-L-2-aminoadipate semialdehyde(2-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78501 chebi_ph7_3 GO:0003007 biolink:BiologicalProcess heart morphogenesis The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. go-plus.json cardiac morphogenesis http://purl.obolibrary.org/obo/GO_0003007 GO:0003006 biolink:BiologicalProcess developmental process involved in reproduction A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. go-plus.json reproductive developmental process|puberty http://purl.obolibrary.org/obo/GO_0003006 CHEBI:78517 biolink:ChemicalSubstance 3'-(L-cysteinyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78517 chebi_ph7_3 CHEBI:78516 biolink:ChemicalSubstance 3'-(L-aspartate)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78516 chebi_ph7_3 GO:0003009 biolink:BiologicalProcess skeletal muscle contraction A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. go-plus.json http://purl.obolibrary.org/obo/GO_0003009 GO:0003008 biolink:BiologicalProcess system process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. go-plus.json organ system process http://purl.obolibrary.org/obo/GO_0003008 CHEBI:78515 biolink:ChemicalSubstance 3'-(L-asparaginyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78515 chebi_ph7_3 GO:0003003 biolink:BiologicalProcess follicular fluid formation in ovarian follicle antrum involved in fused antrum stage The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis. go-plus.json follicular fluid formation in ovarian follicle antrum during fused antrum stage http://purl.obolibrary.org/obo/GO_0003003 GO:0003002 biolink:BiologicalProcess regionalization The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. go-plus.json pattern formation http://purl.obolibrary.org/obo/GO_0003002 GO:0003005 biolink:BiologicalProcess follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis. go-plus.json follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage http://purl.obolibrary.org/obo/GO_0003005 GO:0003004 biolink:BiologicalProcess follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis. go-plus.json follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage http://purl.obolibrary.org/obo/GO_0003004 GO:0003001 biolink:BiologicalProcess obsolete generation of a signal involved in cell-cell signaling OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal. go-plus.json formation of a signal|generation of a signal involved in cell-cell signaling|generation of a signal involved in cell-cell signalling|signal generation http://purl.obolibrary.org/obo/GO_0003001 CHEBI:78513 biolink:ChemicalSubstance 3'-(L-arginyl)adenylyl(1+) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78513 chebi_ph7_3 CHEBI:78512 biolink:ChemicalSubstance 1-decanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78512 PR:000006928 biolink:Protein pro-epidermal growth factor A protein that is a translation product of the human EGF gene or a 1:1 ortholog thereof. go-plus.json EGF http://purl.obolibrary.org/obo/PR_000006928 CHEBI:78529 biolink:ChemicalSubstance 3'-(L-lysyl)adenylyl(1+) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78529 chebi_ph7_3 CHEBI:78528 biolink:ChemicalSubstance 3'-(L-isoleucyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78528 chebi_ph7_3 CHEBI:78527 biolink:ChemicalSubstance 3'-(L-histidyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78527 chebi_ph7_3 CHEBI:78526 biolink:ChemicalSubstance C-terminal-gamma-L-glutamyl-L-lysine(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78526 chebi_ph7_3 CHEBI:136749 biolink:ChemicalSubstance 5-phospho-D-xylonate (3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136749 chebi_ph7_3 CHEBI:136743 biolink:ChemicalSubstance 2-O-[6-O-octanoyl-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136743 chebi_ph7_3 CHEBI:136742 biolink:ChemicalSubstance 2-O-[alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136742 chebi_ph7_3 CHEBI:136746 biolink:ChemicalSubstance 5-phospho-D-xylonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136746 CHEBI:78521 biolink:ChemicalSubstance 3'-(L-glutaminyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78521 chebi_ph7_3 CHEBI:78520 biolink:ChemicalSubstance 3'-(L-glutamate)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78520 chebi_ph7_3 CHEBI:78525 biolink:ChemicalSubstance L-glutamo(2-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78525 chebi_ph7_3 CHEBI:78522 biolink:ChemicalSubstance 3'-glycyladenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78522 chebi_ph7_3 CHEBI:78537 biolink:ChemicalSubstance 3'-(L-valyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78537 chebi_ph7_3 CHEBI:136754 biolink:ChemicalSubstance 5-phospho-L-arabinonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136754 CHEBI:136753 biolink:ChemicalSubstance L-arabino-1,4-lactone-5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136753 chebi_ph7_3 CHEBI:136752 biolink:ChemicalSubstance L-arabino-1,4-lactone-5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136752 CHEBI:136759 biolink:ChemicalSubstance (22E)-3-oxochola-4,22-dien-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136759 chebi_ph7_3 CHEBI:136758 biolink:ChemicalSubstance long-chain 3-oxo-fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136758 chebi_ph7_3 CHEBI:136757 biolink:ChemicalSubstance long-chain (3S)-hydroxy fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136757 chebi_ph7_3 CHEBI:136756 biolink:ChemicalSubstance 5-phospho-L-arabinonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136756 chebi_ph7_3 CHEBI:78532 biolink:ChemicalSubstance 3'-(L-prolyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78532 chebi_ph7_3 CHEBI:78531 biolink:ChemicalSubstance 3'-(L-phenylalanyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78531 chebi_ph7_3 CHEBI:78530 biolink:ChemicalSubstance 3'-(L-methionyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78530 chebi_ph7_3 PR:000006909 biolink:Protein elongation factor 2 A protein that is a translation product of the human EEF2 gene or a 1:1 ortholog thereof. go-plus.json EEF2|EF2|EF-2 http://purl.obolibrary.org/obo/PR_000006909 CHEBI:136751 biolink:ChemicalSubstance D-xylono-1,4-lactone-5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136751 chebi_ph7_3 CHEBI:78536 biolink:ChemicalSubstance 3'-(L-tyrosyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78536 chebi_ph7_3 CHEBI:78535 biolink:ChemicalSubstance 3'-(L-tryptophyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78535 chebi_ph7_3 CHEBI:136750 biolink:ChemicalSubstance D-xylono-1,4-lactone-5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136750 CHEBI:78534 biolink:ChemicalSubstance 3'-(L-threonyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78534 chebi_ph7_3 CHEBI:78533 biolink:ChemicalSubstance 3'-(L-seryl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78533 chebi_ph7_3 GO:0052169 biolink:BiologicalProcess obsolete pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json pathogen-associated molecular pattern dependent modulation by symbiont of host innate immunity http://purl.obolibrary.org/obo/GO_0052169 GO:0052160 biolink:BiologicalProcess modulation by symbiont of host systemic acquired resistance Any process in which a symbiont modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of systemic acquired resistance in host|modulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052160 GO:0052164 biolink:BiologicalProcess symbiont defense to host-produced reactive oxygen species Any process in which a symbiont modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related host ROI production|evasion or tolerance by symbiont of reactive oxygen species produced by other organism involved in symbiotic interaction|response to defense-related host reactive oxygen species production|evasion or tolerance of defense-related host oxidative burst|modulation by organism of defense-related host metabolic burst|evasion or tolerance by organism of host-produced reactive oxygen species|response to defense-related reactive oxygen species production by other organism involved in symbiotic interaction|evasion or tolerance of host-produced AOS|modulation by organism of defense-related host ROS production|modulation by organism of defense-related host active oxygen species production|evasion or tolerance of host-produced reactive oxygen intermediates|modulation by organism of defense-related host respiratory burst|evasion or tolerance of host-produced ROIs|modulation by symbiont of defense-related host reactive oxygen species production|evasion or tolerance of defense-related host metabolic burst|modulation by organism of defense-related host reactive oxygen intermediate production|evasion or tolerance by organism of reactive oxygen species produced by other organism involved in symbiotic interaction|modulation by organism of defense-related host reactive oxidative species production|evasion or tolerance of host-produced active oxygen species|evasion by symbiont of cellular damage caused by host oxidative burst|modulation by organism of defense-related host oxidative burst|evasion or tolerance of host-produced ROS|modulation by organism of defense-related host AOS production|evasion or tolerance by organism of reactive oxygen species produced during host defense response|evasion or tolerance by symbiont of host-produced reactive oxygen species|evasion or tolerance of defense-related host respiratory burst|modulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|evasion or tolerance of reactive oxygen species produced by host http://purl.obolibrary.org/obo/GO_0052164 GO:0052163 biolink:BiologicalProcess symbiont defense to host-produced nitric oxide Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related host NO production|evasion or tolerance of nitric oxide produced by host in response to organism|modulation by symbiont of defense-related host nitric oxide production|evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction|evasion or tolerance by organism of host nitric oxide|evasion or tolerance by organism of host-produced nitric oxide|response to defense-related nitric oxide production by other organism involved in symbiotic interaction|evasion or tolerance of NO produced by host in response to organism|modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|response to defense-related host nitric oxide production|evasion or tolerance by symbiont of host-produced nitric oxide|evasion or tolerance by organism of host NO|evasion or tolerance by organism of host-produced NO|defense response to host innate immune response nitric oxide production http://purl.obolibrary.org/obo/GO_0052163 GO:0052162 biolink:BiologicalProcess modulation by symbiont of defense-related host calcium ion flux Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related host Ca2+ flux|modulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052162 GO:0052161 biolink:BiologicalProcess obsolete modulation by symbiont of defense-related host cell wall thickening OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of host defensive cell wall thickening|modulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052161 GO:0052168 biolink:BiologicalProcess modulation by symbiont of defense-related host calcium-dependent protein kinase pathway Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction|modulation by organism of defense-related host CDPK pathway http://purl.obolibrary.org/obo/GO_0052168 GO:0052167 biolink:BiologicalProcess modulation by symbiont of host innate immune response Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host innate immunity|modulation of host innate immune response|modulation by organism of innate immune response in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052167 GO:0052166 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052166 GO:0052165 biolink:BiologicalProcess symbiont defense to host-produced phytoalexin Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host phytoalexin production|host phytoalexin detoxification|response to host phytoalexin production|evasion or tolerance of phytoalexins produced by host in response to organism|response to phytoalexin production by other organism involved in symbiotic interaction|modulation by organism of phytoalexin production in other organism involved in symbiotic interaction|evasion or tolerance by symbiont of host-produced phytoalexins|phytoalexin detoxification|evasion or tolerance of phytoalexins http://purl.obolibrary.org/obo/GO_0052165 GO:0052171 biolink:BiologicalProcess obsolete growth or development during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. go-plus.json growth or development during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052171 GO:0052170 biolink:BiologicalProcess suppression by symbiont of host innate immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json downregulation by symbiont of host innate immunity|down regulation by symbiont of host innate immunity|inhibition by symbiont of host innate immunity|negative regulation of host innate immune response|down-regulation by symbiont of host innate immunity|negative regulation of innate immune response in other organism|negative regulation by symbiont of host innate immunity|negative regulation by symbiont of host innate immune response http://purl.obolibrary.org/obo/GO_0052170 OBO:uberon/core#posteriorly_connected_to biolink:OntologyClass posteriorly connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. posteriorly_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to GO:0052175 biolink:BiologicalProcess obsolete metabolism by symbiont of host carbohydrate OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052175 GO:0052174 biolink:BiologicalProcess obsolete metabolism by symbiont of host macromolecule OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052174 GO:0052173 biolink:BiologicalProcess response to defenses of other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism. go-plus.json response to defenses of other organism during symbiotic interaction|response to defenses of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052173 GO:0052172 biolink:BiologicalProcess obsolete metabolism by symbiont of host cell wall cellulose OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052172 GO:0052179 biolink:BiologicalProcess obsolete metabolism by symbiont of host cell wall pectin OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052179 GO:0052178 biolink:BiologicalProcess obsolete metabolism by symbiont of host cell wall chitin OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052178 GO:0052177 biolink:BiologicalProcess obsolete metabolism by symbiont of host xylan OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052177 GO:0052176 biolink:BiologicalProcess obsolete metabolism by symbiont of host glucan OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052176 GO:0052182 biolink:BiologicalProcess obsolete modification by host of symbiont morphology or physiology via secreted substance OBSOLETE. The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by a substance secreted by one of the organisms. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052182 GO:0052181 biolink:BiologicalProcess obsolete modulation by host of symbiont defense response OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052181 GO:0052180 biolink:BiologicalProcess obsolete negative regulation of peptidase activity in other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json downregulation of protease activity in other organism during symbiotic interaction|down regulation of protease activity in other organism during symbiotic interaction|inhibition of protease activity in other organism during symbiotic interaction|negative regulation of protease activity in other organism during symbiotic interaction|down-regulation of protease activity in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052180 GO:0052186 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052186 GO:0052185 biolink:BiologicalProcess modification of structure of other organism involved in symbiotic interaction The process in which an organism effects a change in an anatomical part or cellular component of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modification of structure of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052185 GO:0052184 biolink:BiologicalProcess obsolete modulation by organism of symbiont hormone or growth regulator levels OBSOLETE. The alteration by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont hormone or growth regulator levels http://purl.obolibrary.org/obo/GO_0052184 GO:0052183 biolink:BiologicalProcess modification by host of symbiont structure The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052183 GO:0052189 biolink:BiologicalProcess obsolete modulation by symbiont of defense-related host cell wall callose deposition OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of defense-related host callose deposition|modulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|modulation by organism of defense-related callose deposition of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052189 GO:0052188 biolink:BiologicalProcess modification of cellular component in other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or function of a cellular component in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modification of cellular component in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052188 GO:0052187 biolink:BiologicalProcess modification by host of symbiont cellular component The process in which an organism effects a change in the structure or function of a symbiont cellular component. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052187 GO:0052193 biolink:BiologicalProcess obsolete movement in symbiont environment OBSOLETE. The directed movement of an organism or motile cell on, within or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052193 GO:0052192 biolink:BiologicalProcess obsolete movement in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json locomotion in environment of other organism during symbiotic interaction|movement in environment of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052192 GO:0052191 biolink:BiologicalProcess obsolete positive regulation by symbiont of host phagocytosis OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json up regulation by symbiont of host phagocytosis|activation by symbiont of host phagocytosis|stimulation by symbiont of host phagocytosis|up-regulation by symbiont of host phagocytosis|upregulation by symbiont of host phagocytosis http://purl.obolibrary.org/obo/GO_0052191 GO:0052190 biolink:BiologicalProcess obsolete modulation by symbiont of host phagocytosis OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052190 GO:0052197 biolink:BiologicalProcess obsolete positive regulation by host of symbiont defense response OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by host of symbiont defense response|stimulation by host of symbiont defense response|up-regulation by host of symbiont defense response|upregulation by host of symbiont defense response|up regulation by host of symbiont defense response http://purl.obolibrary.org/obo/GO_0052197 GO:0052196 biolink:BiologicalProcess obsolete negative regulation by host of symbiont defense response OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json down-regulation by host of symbiont defense response|inhibition by host of symbiont defense response|down regulation by host of symbiont defense response|downregulation by host of symbiont defense response http://purl.obolibrary.org/obo/GO_0052196 GO:0052195 biolink:BiologicalProcess obsolete movement on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of an organism or motile cell on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json movement on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052195 GO:0052194 biolink:BiologicalProcess obsolete movement on or near symbiont OBSOLETE. The directed movement of an organism or motile cell on or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052194 GO:0052199 biolink:BiologicalProcess obsolete negative regulation of catalytic activity in other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json down-regulation of enzyme activity in other organism during symbiotic interaction|inhibition of enzyme activity in other organism during symbiotic interaction|downregulation of enzyme activity in other organism during symbiotic interaction|inhibition of enzyme activity in other organism|down regulation of enzyme activity in other organism during symbiotic interaction|negative regulation of enzyme activity in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052199 GO:0052198 biolink:BiologicalProcess obsolete modulation of peptidase activity in other organism involved in symbiotic interaction OBSOLETE. The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of protease activity in other organism involved in symbiotic interaction|modulation of protease activity in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052198 CHEBI:146179 biolink:ChemicalSubstance galactotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_146179 GO:0003197 biolink:BiologicalProcess endocardial cushion development The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. go-plus.json http://purl.obolibrary.org/obo/GO_0003197 GO:0003196 biolink:BiologicalProcess ventriculo bulbo valve formation The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003196 GO:0003199 biolink:BiologicalProcess endocardial cushion to mesenchymal transition involved in heart valve formation A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve. go-plus.json endocardial cushion to mesenchymal transition involved in valve formation http://purl.obolibrary.org/obo/GO_0003199 GO:0003198 biolink:BiologicalProcess epithelial to mesenchymal transition involved in endocardial cushion formation A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion. go-plus.json http://purl.obolibrary.org/obo/GO_0003198 GO:0003193 biolink:BiologicalProcess pulmonary valve formation The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003193 CHEBI:146176 biolink:ChemicalSubstance levomethorphan go-plus.json http://purl.obolibrary.org/obo/CHEBI_146176 GO:0003192 biolink:BiologicalProcess mitral valve formation The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003192 GO:0003195 biolink:BiologicalProcess tricuspid valve formation The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003195 CHEBI:146178 biolink:ChemicalSubstance 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_146178 GO:0003194 biolink:BiologicalProcess sinoatrial valve formation The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json SA valve formation http://purl.obolibrary.org/obo/GO_0003194 CHEBI:146181 biolink:ChemicalSubstance mannotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_146181 CHEBI:146180 biolink:ChemicalSubstance glucotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_146180 GO:0003179 biolink:BiologicalProcess heart valve morphogenesis The process in which the structure of a heart valve is generated and organized. go-plus.json heart valve remodeling|heart valve remodelling http://purl.obolibrary.org/obo/GO_0003179 GO:0003178 biolink:BiologicalProcess coronary sinus valve development The progression of the valve of the coronary sinus over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003178 GO:0003175 biolink:BiologicalProcess tricuspid valve development The progression of the tricuspid valve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003175 GO:0003174 biolink:BiologicalProcess mitral valve development The progression of the mitral valve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003174 GO:0003177 biolink:BiologicalProcess pulmonary valve development The progression of the pulmonary valve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003177 GO:0003176 biolink:BiologicalProcess aortic valve development The progression of the aortic valve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003176 GO:0003171 biolink:BiologicalProcess atrioventricular valve development The progression of the atrioventricular valve over time, from its formation to the mature structure. go-plus.json AV valve development http://purl.obolibrary.org/obo/GO_0003171 GO:0003170 biolink:BiologicalProcess heart valve development The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. go-plus.json cardiac valve development http://purl.obolibrary.org/obo/GO_0003170 GO:0003173 biolink:BiologicalProcess ventriculo bulbo valve development The progression of the ventriculo bulbo valve over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003173 GO:0003172 biolink:BiologicalProcess sinoatrial valve development The progression of the sinoatrial valve over time, from its formation to the mature structure. go-plus.json SA valve development http://purl.obolibrary.org/obo/GO_0003172 GO:0003180 biolink:BiologicalProcess aortic valve morphogenesis The process in which the structure of the aortic valve is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003180 GO:0003189 biolink:BiologicalProcess aortic valve formation The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003189 GO:0003186 biolink:BiologicalProcess tricuspid valve morphogenesis The process in which the structure of the tricuspid valve is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003186 GO:0003185 biolink:BiologicalProcess sinoatrial valve morphogenesis The process in which the structure of the sinoatrial valve is generated and organized. go-plus.json SA valve morphogenesis http://purl.obolibrary.org/obo/GO_0003185 GO:0003188 biolink:BiologicalProcess heart valve formation The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003188 CHEBI:146140 biolink:ChemicalSubstance 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_146140 chebi_ph7_3 GO:0003187 biolink:BiologicalProcess ventriculo bulbo valve morphogenesis The process in which the structure of the ventriculo bulbo valve is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003187 GO:0003182 biolink:BiologicalProcess coronary sinus valve morphogenesis The process in which the structure of the coronary sinus valve is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003182 GO:0003181 biolink:BiologicalProcess atrioventricular valve morphogenesis The process in which the structure of the atrioventricular valve is generated and organized. go-plus.json AV valve morphogenesis http://purl.obolibrary.org/obo/GO_0003181 GO:0003184 biolink:BiologicalProcess pulmonary valve morphogenesis The process in which the structure of the pulmonary valve is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003184 GO:0003183 biolink:BiologicalProcess mitral valve morphogenesis The process in which the structure of the mitral valve is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003183 GO:0003191 biolink:BiologicalProcess coronary sinus valve formation The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json http://purl.obolibrary.org/obo/GO_0003191 GO:0003190 biolink:BiologicalProcess atrioventricular valve formation The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. go-plus.json AV valve formation http://purl.obolibrary.org/obo/GO_0003190 CHEBI:30528 biolink:ChemicalSubstance vanadium oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_30528 CHEBI:30527 biolink:ChemicalSubstance flavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_30527 CHEBI:30526 biolink:ChemicalSubstance 1-aminocyclopropanecarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30526 GO:0042761 biolink:BiologicalProcess very long-chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22. MetaCyc:PWY-5080 go-plus.json very-long-chain fatty acid biosynthesis|very-long-chain fatty acid biosynthetic process|very-long-chain fatty acid anabolism|very-long-chain fatty acid synthesis|very-long-chain fatty acid formation http://purl.obolibrary.org/obo/GO_0042761 GO:0042760 biolink:BiologicalProcess very long-chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain length greater than C22. go-plus.json very-long-chain fatty acid breakdown|very-long-chain fatty acid catabolism|very-long-chain fatty acid catabolic process|very-long-chain fatty acid degradation http://purl.obolibrary.org/obo/GO_0042760 GO:0042763 biolink:CellularComponent intracellular immature spore A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants. go-plus.json forespore http://purl.obolibrary.org/obo/GO_0042763 GO:0042762 biolink:BiologicalProcess regulation of sulfur metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. go-plus.json regulation of sulfur metabolism|regulation of sulphur metabolism|regulation of sulphur metabolic process http://purl.obolibrary.org/obo/GO_0042762 GO:0042769 biolink:BiologicalProcess DNA damage response, detection of DNA damage The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal. go-plus.json DNA damage response, perception of DNA damage|detection of DNA damage during DNA damage response http://purl.obolibrary.org/obo/GO_0042769 CL:1000850 biolink:Cell macula densa epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000850 GO:0042768 biolink:MolecularActivity ecdysteroid 2-hydroxylase activity Catalysis of the hydroxylation of an ecdysteroid at carbon position 2. go-plus.json http://purl.obolibrary.org/obo/GO_0042768 GO:0042765 biolink:CellularComponent GPI-anchor transamidase complex An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor. go-plus.json GPIT complex http://purl.obolibrary.org/obo/GO_0042765 GO:0042764 biolink:CellularComponent ascospore-type prospore An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0042764 GO:0042767 biolink:MolecularActivity ecdysteroid 22-hydroxylase activity Catalysis of the hydroxylation of an ecdysteroid at carbon position 22. go-plus.json http://purl.obolibrary.org/obo/GO_0042767 GO:0042766 biolink:BiologicalProcess nucleosome mobilization The movement of nucleosomes along a DNA fragment. go-plus.json nucleosome sliding http://purl.obolibrary.org/obo/GO_0042766 CL:1000849 biolink:Cell kidney distal convoluted tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000849 GO:0042772 biolink:BiologicalProcess DNA damage response, signal transduction resulting in transcription A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0042772 GO:0042771 biolink:BiologicalProcess intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. go-plus.json DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis http://purl.obolibrary.org/obo/GO_0042771 GO:0042774 biolink:BiologicalProcess plasma membrane ATP synthesis coupled electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0042774 GO:0042773 biolink:BiologicalProcess ATP synthesis coupled electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP. go-plus.json http://purl.obolibrary.org/obo/GO_0042773 GO:0042770 biolink:BiologicalProcess signal transduction in response to DNA damage A cascade of processes induced by the detection of DNA damage within a cell. go-plus.json response to DNA damage stimulus by intracellular signaling cascade|DNA damage response, signal transduction http://purl.obolibrary.org/obo/GO_0042770 GO:0042779 biolink:BiologicalProcess tRNA 3'-trailer cleavage Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both. go-plus.json removal of tRNA 3'-trailer sequence|tRNA 3'-end cleavage http://purl.obolibrary.org/obo/GO_0042779 GO:0042776 biolink:BiologicalProcess mitochondrial ATP synthesis coupled proton transport The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. go-plus.json mitochondrial proton transport http://purl.obolibrary.org/obo/GO_0042776 GO:0042775 biolink:BiologicalProcess mitochondrial ATP synthesis coupled electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane. go-plus.json organelle ATP synthesis coupled electron transport|mitochondrial electron transport http://purl.obolibrary.org/obo/GO_0042775 GO:0042778 biolink:BiologicalProcess tRNA end turnover The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0042778 GO:0042777 biolink:BiologicalProcess plasma membrane ATP synthesis coupled proton transport The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. go-plus.json ATP synthesis coupled proton transport http://purl.obolibrary.org/obo/GO_0042777 CHEBI:30531 biolink:ChemicalSubstance pimelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30531 GO:0052106 biolink:BiologicalProcess obsolete quorum sensing involved in interaction with host OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json quorum sensing during interaction with host http://purl.obolibrary.org/obo/GO_0052106 GO:0052105 biolink:BiologicalProcess obsolete induction by symbiont of defense-related host cell wall thickening OBSOLETE. The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host cell wall thickening|positive regulation by organism of host defensive cell wall thickening|activation by organism of host defensive cell wall thickening|up regulation by symbiont of defense-related host cell wall thickening|activation by symbiont of defense-related host cell wall thickening|positive regulation by symbiont of defense-related host cell wall thickening|positive regulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|induction by organism of host defensive cell wall thickening|stimulation by symbiont of defense-related host cell wall thickening|up-regulation by symbiont of defense-related host cell wall thickening|activation by organism of defense-related host cell wall thickening http://purl.obolibrary.org/obo/GO_0052105 GO:0052104 biolink:BiologicalProcess induction by symbiont of host systemic acquired resistance Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of SAR in host|induction by organism of systemic acquired resistance in other organism involved in symbiotic interaction|up-regulation by symbiont of systemic acquired resistance in host|stimulation by symbiont of systemic acquired resistance in host|induction by organism of SAR in host|positive regulation by symbiont of host systemic acquired resistance|positive regulation by symbiont of systemic acquired resistance in host|up regulation by symbiont of systemic acquired resistance in host|positive regulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction|activation by organism of systemic acquired resistance in host|induction by symbiont of systemic acquired resistance in host|upregulation by symbiont of systemic acquired resistance in host http://purl.obolibrary.org/obo/GO_0052104 GO:0052103 biolink:BiologicalProcess induction by symbiont of host induced systemic resistance Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host induced systemic resistance|induction by organism of ISR in host|induction by organism of induced systemic resistance in other organism involved in symbiotic interaction|induction by symbiont of induced systemic resistance in host|up-regulation by symbiont of induced systemic resistance in host|activation by organism of induced systemic resistance in host|upregulation by symbiont of induced systemic resistance in host|positive regulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|activation by symbiont of induced systemic resistance in host|stimulation by symbiont of induced systemic resistance in host|up regulation by symbiont of induced systemic resistance in host|activation by organism of ISR in host|positive regulation by symbiont of induced systemic resistance in host http://purl.obolibrary.org/obo/GO_0052103 CHEBI:29519 biolink:ChemicalSubstance aphidicolan-16beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29519 chebi_ph7_3 CHEBI:29514 biolink:ChemicalSubstance 5-amino-5-deoxy-3-dehydroshikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29514 GO:0052109 biolink:BiologicalProcess obsolete induction by symbiont of defense-related host cell wall callose deposition OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of defense-related host callose deposition|positive regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host cell wall callose deposition|positive regulation by symbiont of defense-related host cell wall callose deposition|activation by symbiont of defense-related host cell wall callose deposition|positive regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|stimulation by symbiont of defense-related host cell wall callose deposition|up-regulation by symbiont of defense-related host cell wall callose deposition|upregulation by symbiont of defense-related host cell wall callose deposition http://purl.obolibrary.org/obo/GO_0052109 GO:0052108 biolink:BiologicalProcess obsolete growth or development of symbiont during interaction with host OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json growth or development of symbiont during interaction with host|growth or development of organism during interaction with host|growth or development of organism in response to host http://purl.obolibrary.org/obo/GO_0052108 GO:0052107 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052107 GO:0042783 biolink:BiologicalProcess evasion of host immune response A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json active immune evasion|passive evasion of host immune response|active evasion of host immune response|evasion or tolerance of host immune response|passive evasion of immune response of other organism involved in symbiotic interaction|mitigation of host immune response|immune evasion|active evasion of immune response of other organism involved in symbiotic interaction|passive immune evasion http://purl.obolibrary.org/obo/GO_0042783 UBERON:0007590 biolink:AnatomicalEntity cuboidal oviduct epithelium A cuboidal epithelium that is part of a oviduct. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007590 CHEBI:29510 biolink:ChemicalSubstance abietol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29510 chebi_ph7_3 GO:0042782 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042782 GO:0042785 biolink:BiologicalProcess evasion of host immune response via regulation of host cytokine network Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json active evasion of host immune response via regulation of host cytokine network|active immune evasion via modulation of host cytokine network|active immune evasion via regulation of host cytokine network|active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0042785 GO:0042784 biolink:BiologicalProcess evasion of host immune response via regulation of host complement system Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json active evasion of host immune response via regulation of host complement system|active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction|active immune evasion via regulation of host complement system|active immune evasion via modulation of host complement system http://purl.obolibrary.org/obo/GO_0042784 GO:0042781 biolink:MolecularActivity 3'-tRNA processing endoribonuclease activity Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule. EC:3.1.26.11|MetaCyc:3.1.26.11-RXN go-plus.json tRNA 3 endonuclease activity|3 tRNase activity|tRNAse Z|RNase Z activity|3' tRNA processing endoribonuclease activity|ribonuclease Z activity|tRNA 3' endonuclease activity|3' tRNase activity http://purl.obolibrary.org/obo/GO_0042781 GO:0042780 biolink:BiologicalProcess tRNA 3'-end processing The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA. go-plus.json tRNA 3' processing http://purl.obolibrary.org/obo/GO_0042780 GO:0042787 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042787 GO:0042786 biolink:BiologicalProcess evasion of host immune response via regulation of host antigen processing and presentation Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json active immune evasion via regulation of antigen processing and presentation|active evasion of host immune response via regulation of host antigen processing and presentation pathway|active immune evasion via modulation of antigen processing/presentation|active evasion of host immune response via regulation of host antigen processing and presentation|active immune evasion via modulation of antigen processing and presentation|active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0042786 UBERON:0007592 biolink:AnatomicalEntity ciliated columnar epithelium Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0007592 GO:0042789 biolink:BiologicalProcess mRNA transcription by RNA polymerase II The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. go-plus.json mRNA transcription from RNA polymerase II promoter|mRNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0042789 GO:0042788 biolink:CellularComponent polysomal ribosome A ribosome bound to mRNA that forms part of a polysome. go-plus.json active ribosome http://purl.obolibrary.org/obo/GO_0042788 GO:0052102 biolink:BiologicalProcess positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json up-regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|upregulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation of defense-related host CDPK pathway by organism|up regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|activation by symbiont of defense-related host calcium-dependent protein kinase pathway|stimulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052102 GO:0052101 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052101 GO:0052100 biolink:BiologicalProcess obsolete intraspecies quorum sensing OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0052100 GO:0052117 biolink:BiologicalProcess obsolete aerotaxis in host environment OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json aerotaxis in response to host environment http://purl.obolibrary.org/obo/GO_0052117 GO:0052116 biolink:BiologicalProcess obsolete chemotaxis in host environment OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json chemotaxis in response to host environment http://purl.obolibrary.org/obo/GO_0052116 GO:0052115 biolink:BiologicalProcess obsolete energy taxis in host environment OBSOLETE. The directed movement of a motile cell or organism in the environment of its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json energy taxis in response to host environment http://purl.obolibrary.org/obo/GO_0052115 GO:0052114 biolink:BiologicalProcess obsolete adaptation to host pH environment OBSOLETE. The responsive adjustment of an organism to the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adaptation to host pH environment|pH tolerance to host environment http://purl.obolibrary.org/obo/GO_0052114 CHEBI:30514 biolink:ChemicalSubstance caesium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_30514 chebi_ph7_3 CHEBI:30513 biolink:ChemicalSubstance antimony atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_30513 chebi_ph7_3 GO:0052119 biolink:BiologicalProcess obsolete negative energy taxis in host environment OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative energy taxis in response to host environment http://purl.obolibrary.org/obo/GO_0052119 CHEBI:30512 biolink:ChemicalSubstance silver atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_30512 chebi_ph7_3 GO:0052118 biolink:BiologicalProcess obsolete positive energy taxis in host environment OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive energy taxis in response to host environment http://purl.obolibrary.org/obo/GO_0052118 GO:0042794 biolink:BiologicalProcess plastid rRNA transcription The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase. go-plus.json rRNA transcription from plastid promoter http://purl.obolibrary.org/obo/GO_0042794 GO:0042793 biolink:BiologicalProcess plastid transcription The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase. go-plus.json transcription from plastid promoter http://purl.obolibrary.org/obo/GO_0042793 GO:0042796 biolink:BiologicalProcess snRNA transcription by RNA polymerase III The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter. go-plus.json snRNA transcription from RNA polymerase III promoter|snRNA transcription from Pol III promoter http://purl.obolibrary.org/obo/GO_0042796 GO:0042795 biolink:BiologicalProcess snRNA transcription by RNA polymerase II The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter. go-plus.json snRNA transcription from RNA polymerase II promoter|snRNA transcription from Pol II promoter http://purl.obolibrary.org/obo/GO_0042795 GO:0042790 biolink:BiologicalProcess nucleolar large rRNA transcription by RNA polymerase I The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I. go-plus.json transcription of nucleolar large rRNA by RNA polymerase I|transcription of nuclear rRNA large Pol I transcript|transcription of nuclear large rRNA transcript from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0042790 GO:0042792 biolink:BiologicalProcess mitochondrial rRNA transcription The synthesis of ribosomal RNA (rRNA) from a mitochondrial DNA template. go-plus.json rRNA transcription from mitochondrial promoter http://purl.obolibrary.org/obo/GO_0042792 GO:0042791 biolink:BiologicalProcess 5S class rRNA transcription by RNA polymerase III The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter. go-plus.json 5S rRNA transcription|5S class rRNA transcription from RNA polymerase III type 1 promoter http://purl.obolibrary.org/obo/GO_0042791 GO:0042798 biolink:BiologicalProcess obsolete protein neddylation during NEDD8 class-dependent protein catabolic process OBSOLETE. Covalent attachment of the ubiquitin-like protein NEDD8 (or equivalent protein) to another protein, as a part of NEDD8-dependant protein catabolism. go-plus.json protein neddylation during NEDD8 class-dependent protein degradation|protein neddylation during NEDD8 class-dependent protein breakdown|protein neddylation during NEDD8 class-dependent protein catabolic process|protein neddylation during RUB1-dependent protein catabolism|protein neddylation during RUB1-dependent protein catabolic process|protein neddylation during NEDD8 class-dependent protein catabolism http://purl.obolibrary.org/obo/GO_0042798 GO:0042797 biolink:BiologicalProcess tRNA transcription by RNA polymerase III The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter. go-plus.json tRNA transcription from Pol III promoter|tRNA transcription from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_0042797 GO:0042799 biolink:MolecularActivity histone methyltransferase activity (H4-K20 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein. Reactome:R-HSA-2301205|Reactome:R-HSA-5682965 go-plus.json histone methylase activity (H4-K20 specific)|histone lysine N-methyltransferase activity (H4-K20 specific)|histone H4 lysine 20-specific methyltransferase activity http://purl.obolibrary.org/obo/GO_0042799 GO:0052113 biolink:BiologicalProcess obsolete adaptation to host osmotic environment OBSOLETE. The responsive adjustment of an organism to the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json adaptation to host osmotic environment|osmotic tolerance to host environment http://purl.obolibrary.org/obo/GO_0052113 GO:0052112 biolink:BiologicalProcess occlusion by symbiont of host xylem The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052112 UBERON:0007589 biolink:AnatomicalEntity ciliated columnar oviduct epithelium A ciliated columnar epithelium that is part of a oviduct. go-plus.json epithelium of uterine tube|uterine tube epithelium http://purl.obolibrary.org/obo/UBERON_0007589 GO:0052111 biolink:BiologicalProcess modification by symbiont of host structure The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052111 GO:0052110 biolink:BiologicalProcess occlusion by symbiont of host vascular system The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052110 GO:0052128 biolink:BiologicalProcess positive energy taxis The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. go-plus.json http://purl.obolibrary.org/obo/GO_0052128 GO:0052127 biolink:BiologicalProcess obsolete movement on or near host OBSOLETE. The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052127 GO:0052126 biolink:BiologicalProcess movement in host environment The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json movement in response to host http://purl.obolibrary.org/obo/GO_0052126 GO:0052125 biolink:BiologicalProcess obsolete energy taxis on or near host OBSOLETE. The directed movement of a motile cell or organism on or near its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052125 GO:0052129 biolink:BiologicalProcess negative energy taxis The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. go-plus.json http://purl.obolibrary.org/obo/GO_0052129 GO:0052120 biolink:BiologicalProcess obsolete positive aerotaxis in host environment OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive aerotaxis in response to host environment http://purl.obolibrary.org/obo/GO_0052120 GO:0052124 biolink:BiologicalProcess obsolete energy taxis within host OBSOLETE. The directed movement of a motile cell or organism within its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052124 GO:0052123 biolink:BiologicalProcess obsolete negative chemotaxis in host environment OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative chemotaxis in response to host environment http://purl.obolibrary.org/obo/GO_0052123 GO:0052122 biolink:BiologicalProcess obsolete negative aerotaxis in host environment OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative aerotaxis in response to host environment http://purl.obolibrary.org/obo/GO_0052122 GO:0052121 biolink:BiologicalProcess obsolete positive chemotaxis in host environment OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive chemotaxis in response to host environment http://purl.obolibrary.org/obo/GO_0052121 GO:0052139 biolink:BiologicalProcess obsolete negative chemotaxis in host OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative chemotaxis within host http://purl.obolibrary.org/obo/GO_0052139 CHEBI:29507 biolink:ChemicalSubstance 3-amino-5-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29507 GO:0052138 biolink:BiologicalProcess obsolete aerotaxis on or near host OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052138 CHEBI:29509 biolink:ChemicalSubstance abietal go-plus.json http://purl.obolibrary.org/obo/CHEBI_29509 chebi_ph7_3 GO:0052137 biolink:BiologicalProcess obsolete aerotaxis in host OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json aerotaxis within host http://purl.obolibrary.org/obo/GO_0052137 GO:0052136 biolink:BiologicalProcess obsolete negative chemotaxis on or near host OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052136 CHEBI:29505 biolink:ChemicalSubstance A47934 go-plus.json http://purl.obolibrary.org/obo/CHEBI_29505 GO:0052131 biolink:BiologicalProcess positive aerotaxis The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen. go-plus.json http://purl.obolibrary.org/obo/GO_0052131 GO:0052130 biolink:BiologicalProcess negative aerotaxis The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen. go-plus.json http://purl.obolibrary.org/obo/GO_0052130 GO:0052135 biolink:BiologicalProcess obsolete negative aerotaxis in host OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative aerotaxis within host http://purl.obolibrary.org/obo/GO_0052135 GO:0052134 biolink:BiologicalProcess obsolete negative aerotaxis on or near host OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052134 GO:0052133 biolink:BiologicalProcess obsolete positive aerotaxis in host OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive aerotaxis within host http://purl.obolibrary.org/obo/GO_0052133 GO:0052132 biolink:BiologicalProcess obsolete positive aerotaxis on or near host OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052132 GO:0052149 biolink:BiologicalProcess obsolete modulation by symbiont of host peptidase activity OBSOLETE. The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by symbiont of host protease activity http://purl.obolibrary.org/obo/GO_0052149 GO:0052148 biolink:BiologicalProcess modulation by symbiont of host catalytic activity The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation of catalytic activity of host by symbiont|modulation by symbiont of host enzyme activity|regulation of host catalytic activity by symbiont|regulation by symbiont of host catalytic activity|regulation of catalytic activity of host by symbiont http://purl.obolibrary.org/obo/GO_0052148 GO:0052147 biolink:BiologicalProcess obsolete positive energy taxis in host OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive energy taxis within host http://purl.obolibrary.org/obo/GO_0052147 CL:1000839 biolink:Cell kidney proximal straight tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000839 CL:1000838 biolink:Cell kidney proximal convoluted tubule epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000838 GO:0052142 biolink:BiologicalProcess obsolete chemotaxis within host OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052142 GO:0052141 biolink:BiologicalProcess obsolete positive chemotaxis on or near host OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052141 GO:0052140 biolink:BiologicalProcess obsolete positive chemotaxis in host OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive chemotaxis within host http://purl.obolibrary.org/obo/GO_0052140 GO:0052146 biolink:BiologicalProcess obsolete positive energy taxis on or near host OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052146 GO:0052145 biolink:BiologicalProcess obsolete negative energy taxis on or near host OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052145 GO:0052144 biolink:BiologicalProcess obsolete negative energy taxis in host OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative energy taxis within host http://purl.obolibrary.org/obo/GO_0052144 GO:0052143 biolink:BiologicalProcess obsolete chemotaxis on or near host involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json chemotaxis on or near host during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052143 GO:0052159 biolink:BiologicalProcess modulation by symbiont of host induced systemic resistance Any process in which a symbiont modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|modulation by symbiont of induced systemic resistance in host http://purl.obolibrary.org/obo/GO_0052159 GO:0052158 biolink:BiologicalProcess modulation by symbiont of host resistance gene-dependent defense response Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont|modulation by organism of defense response in host by specific elicitors|modulation by organism of host gene-for-gene resistance http://purl.obolibrary.org/obo/GO_0052158 GO:0052153 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052153 GO:0052152 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052152 GO:0052151 biolink:BiologicalProcess positive regulation by symbiont of host apoptotic process Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json induction by symbiont of host apoptosis|activation by organism of host apoptosis|activation by organism of host apoptotic programmed cell death|stimulation by symbiont of host apoptosis|activation by symbiont of host apoptosis|up-regulation by symbiont of host apoptosis|positive regulation by organism of host apoptotic programmed cell death|up regulation by organism of host apoptotic programmed cell death|positive regulation by symbiont of host apoptosis|up regulation by symbiont of host apoptosis|upregulation by organism of host apoptotic programmed cell death|induction by organism of host apoptotic programmed cell death|up-regulation by organism of host apoptotic programmed cell death|upregulation by symbiont of host apoptosis http://purl.obolibrary.org/obo/GO_0052151 GO:0052150 biolink:BiologicalProcess modulation by symbiont of host apoptotic process Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of host apoptotic programmed cell death|modulation by symbiont of host apoptosis http://purl.obolibrary.org/obo/GO_0052150 GO:0052157 biolink:BiologicalProcess obsolete modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response OBSOLETE. Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of microbe-associated molecular pattern-induced innate immune response in other organism involved in symbiotic interaction|modulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|modulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity http://purl.obolibrary.org/obo/GO_0052157 GO:0052156 biolink:BiologicalProcess modulation by symbiont of host T-cell mediated immune response Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052156 GO:0052155 biolink:BiologicalProcess modulation by symbiont of host cell-mediated immune response Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|modulation by organism of host cell-based immune response http://purl.obolibrary.org/obo/GO_0052155 GO:0052154 biolink:BiologicalProcess modulation by symbiont of host B-cell mediated immune response Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction|regulation by organism of host B-cell mediated immune response http://purl.obolibrary.org/obo/GO_0052154 CHEBI:78429 biolink:ChemicalSubstance 1-alkyl-2-acyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78429 chebi_ph7_3 CHEBI:78428 biolink:ChemicalSubstance 1-alkyl-2-acyl-3-(beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78428 chebi_ph7_3 OBO:GOCHE_23924 biolink:OntologyClass substance with enzyme inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_23924 3_STAR CHEBI:136849 biolink:ChemicalSubstance 3-oxo-Delta(4)-steroid group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136849 chebi_ph7_3 CHEBI:136848 biolink:ChemicalSubstance beta-bitter acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136848 UBERON:0007652 biolink:AnatomicalEntity esophageal sphincter A sphincter that is part of an esophagus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007652 CHEBI:136842 biolink:ChemicalSubstance tenuazonic acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136842 chebi_ph7_3 UBERON:0007651 biolink:AnatomicalEntity anatomical junction An anatomical structure that connects two structures go-plus.json junction|anatomical junction http://purl.obolibrary.org/obo/UBERON_0007651 CHEBI:136841 biolink:ChemicalSubstance nickel-sirohydrochlorin(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136841 chebi_ph7_3 CHEBI:136840 biolink:ChemicalSubstance pheophytin a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136840 chebi_ph7_3 CHEBI:30488 biolink:ChemicalSubstance sulfonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_30488 CHEBI:78421 biolink:ChemicalSubstance 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78421 chebi_ph7_3 CHEBI:30485 biolink:ChemicalSubstance selenonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_30485 chebi_ph7_3 CHEBI:78426 biolink:ChemicalSubstance 1-(3-O-sulfo-beta-D-galactosyl-(1->4)-beta-D-glucosyl)-N-acylsphingosine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78426 chebi_ph7_3 CHEBI:78424 biolink:ChemicalSubstance 18-hydroxyoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78424 chebi_ph7_3 CHEBI:78423 biolink:ChemicalSubstance (R)-11-hydroxylaurate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78423 chebi_ph7_3 CHEBI:78438 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78438 chebi_ph7_3 NCBITaxon:7898 biolink:OrganismalEntity Actinopterygii go-plus.json Actinopterygi|bony fishes|fishes|ray-finned fishes|fish|Osteichthyes http://purl.obolibrary.org/obo/NCBITaxon_7898 CHEBI:136859 biolink:ChemicalSubstance pro-agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_136859 CHEBI:136853 biolink:ChemicalSubstance 3-(acyloxy)acyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136853 chebi_ph7_3 CHEBI:30490 biolink:ChemicalSubstance tetrahydridooxygen(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30490 UBERON:0007641 biolink:AnatomicalEntity trigeminal nuclear complex The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]. go-plus.json nuclei trigemini|trigeminal nuclei http://purl.obolibrary.org/obo/UBERON_0007641 CHEBI:136852 biolink:ChemicalSubstance adlupulone go-plus.json http://purl.obolibrary.org/obo/CHEBI_136852 CHEBI:136851 biolink:ChemicalSubstance colupulone go-plus.json http://purl.obolibrary.org/obo/CHEBI_136851 CHEBI:136858 biolink:ChemicalSubstance beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_136858 CHEBI:136857 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136857 chebi_ph7_3 CHEBI:136856 biolink:ChemicalSubstance O-succinyl-L-serinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136856 chebi_ph7_3 CHEBI:78433 biolink:ChemicalSubstance refrigerant go-plus.json http://purl.obolibrary.org/obo/CHEBI_78433 UBERON:0007647 biolink:AnatomicalEntity ectomeninx The outermost layer of the mesenchymal capsule that surrounds the developing brain, of mixed paraxial mesoderm and neural crest origin. The ectomeninx forms the dura mater (both inner layer and outer chondrogenic layer). go-plus.json future dura mater http://purl.obolibrary.org/obo/UBERON_0007647 CHEBI:78430 biolink:ChemicalSubstance 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78430 chebi_ph7_3 UBERON:0007646 biolink:AnatomicalEntity endomeninx The innermost layer of the mesenchymal capsule that surrounds the developing brain, primarily of neural crest origin. The endomeninx forms the leptomeninx. go-plus.json future leptomeninx|future leptomeninges http://purl.obolibrary.org/obo/UBERON_0007646 CHEBI:78437 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_78437 CHEBI:136850 biolink:ChemicalSubstance 2-acyl-4,6-diprenylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136850 UBERON:0007645 biolink:AnatomicalEntity future meninx A developing mesenchymal capsule that covers the developing brain and spinal cord and is the precursor of the meningeal cluster. In mammals this gives rise to the arachnoid mater, pia mater and dura mater. In cyclostomes and fishes, the future meninx gives rise to a single meningeal layer, the primitive meninx. go-plus.json primordial meninx|primary meninx|meninx primitiva|primitive meninx http://purl.obolibrary.org/obo/UBERON_0007645 CHEBI:78436 biolink:ChemicalSubstance ganglioside GD3(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78436 chebi_ph7_3 UBERON:0007644 biolink:AnatomicalEntity thoracic lymph node A lymph node that is part of a thorax. Includes lymph nodes of the lungs and mediastinal lymph nodes go-plus.json deep thoracic lymph node|lymph node of thorax http://purl.obolibrary.org/obo/UBERON_0007644 CHEBI:78435 biolink:ChemicalSubstance [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphospho-ditrans,polycis-undecaprenol polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78435 chebi_ph7_3 CHEBI:30492 biolink:ChemicalSubstance dioxidaniumyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_30492 CHEBI:78449 biolink:ChemicalSubstance O-(S-malonylpantetheine-4'-phosphoryl)serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78449 chebi_ph7_3 CHEBI:136829 biolink:ChemicalSubstance 1-aci-nitro-2-(phenyl)ethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_136829 chebi_ph7_3 CHEBI:136828 biolink:ChemicalSubstance 4'-O-methylxanthohumol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136828 CHEBI:29476 biolink:ChemicalSubstance 3-amino-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29476 CHEBI:136826 biolink:ChemicalSubstance xanthogalenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136826 CHEBI:29472 biolink:ChemicalSubstance 2-heptyl-3-hydroxy-4-quinolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_29472 chebi_ph7_3 CHEBI:29474 biolink:ChemicalSubstance (S)-3,5-dihydroxyphenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_29474 GO:0042703 biolink:BiologicalProcess menstruation The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus. Wikipedia:Menstruation go-plus.json http://purl.obolibrary.org/obo/GO_0042703 gocheck_do_not_annotate CHEBI:136821 biolink:ChemicalSubstance RNA polyanion nucleotide 2'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136821 chebi_ph7_3 CHEBI:136820 biolink:ChemicalSubstance RNA polyanion 2',3'-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136820 chebi_ph7_3 GO:0042702 biolink:BiologicalProcess uterine wall growth The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels. go-plus.json http://purl.obolibrary.org/obo/GO_0042702 GO:0042705 biolink:BiologicalProcess ocellus photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus. go-plus.json http://purl.obolibrary.org/obo/GO_0042705 GO:0042704 biolink:BiologicalProcess uterine wall breakdown The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels. go-plus.json http://purl.obolibrary.org/obo/GO_0042704 CHEBI:136825 biolink:ChemicalSubstance (E)-1-(glycyl-L-cystein-S-yl)-omega-(methylthio)alkylhydroximate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136825 chebi_ph7_3 CHEBI:136824 biolink:ChemicalSubstance mandelamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136824 chebi_ph7_3 CHEBI:136823 biolink:ChemicalSubstance alpha-D-Glcp-(1->6)-alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->6)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_136823 chebi_ph7_3 GO:0042701 biolink:BiologicalProcess progesterone secretion The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta. go-plus.json http://purl.obolibrary.org/obo/GO_0042701 GO:0042700 biolink:BiologicalProcess luteinizing hormone signaling pathway The series of molecular signals mediated by luteinizing hormone. go-plus.json luteinizing hormone signalling pathway http://purl.obolibrary.org/obo/GO_0042700 CHEBI:136822 biolink:ChemicalSubstance cyclobis-(1->6)-alpha-nigerosyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_136822 chebi_ph7_3 CHEBI:78444 biolink:ChemicalSubstance EC 3.1.1.1 (carboxylesterase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_78444 CHEBI:30465 biolink:ChemicalSubstance tellurous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30465 CHEBI:78442 biolink:ChemicalSubstance AMP 3'-end(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78442 chebi_ph7_3 GO:0042707 biolink:BiologicalProcess ocellus photoreceptor cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. go-plus.json http://purl.obolibrary.org/obo/GO_0042707 UBERON:0007635 biolink:AnatomicalEntity nucleus of medulla oblongata A neural nucleus that is part of a medulla oblongata. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007635 GO:0042706 biolink:BiologicalProcess eye photoreceptor cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. go-plus.json http://purl.obolibrary.org/obo/GO_0042706 CHEBI:78447 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78447 chebi_ph7_3 GO:0042709 biolink:CellularComponent succinate-CoA ligase complex A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP. go-plus.json http://purl.obolibrary.org/obo/GO_0042709 CHEBI:78446 biolink:ChemicalSubstance O-(S-acetylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78446 chebi_ph7_3 GO:0042708 biolink:MolecularActivity obsolete elastase activity OBSOLETE. Catalysis of the hydrolysis of elastin. go-plus.json elastase activity http://purl.obolibrary.org/obo/GO_0042708 CHEBI:78445 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78445 chebi_ph7_3 CL:1000909 biolink:Cell kidney loop of Henle epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000909 UBERON:0007619 biolink:AnatomicalEntity limiting membrane of retina go-plus.json retina lamina http://purl.obolibrary.org/obo/UBERON_0007619 CHEBI:29484 biolink:ChemicalSubstance (S)-4,5-dihydroxypentane-2,3-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_29484 chebi_ph7_3 CHEBI:136832 biolink:ChemicalSubstance Cys(IAN)-Gly zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136832 chebi_ph7_3 GO:0042714 biolink:BiologicalProcess dosage compensation complex assembly The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0042714 CHEBI:29491 biolink:ChemicalSubstance 5-O-beta-D-mycaminosyltylactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_29491 GO:0042713 biolink:BiologicalProcess sperm ejaculation The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. go-plus.json http://purl.obolibrary.org/obo/GO_0042713 CHEBI:136831 biolink:ChemicalSubstance S-[(E)-N-hydroxy-2-(indol-3-yl)ethanimidoyl]-L-cysteinylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136831 chebi_ph7_3 GO:0042716 biolink:CellularComponent plasma membrane-derived chromatophore A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria. go-plus.json chromatophore vesicle http://purl.obolibrary.org/obo/GO_0042716 CHEBI:136830 biolink:ChemicalSubstance S-[(Z)-N-hydroxy-2-phenylethanimidoyl]-L-cysteinylglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136830 chebi_ph7_3 GO:0042715 biolink:BiologicalProcess dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes. An example of this process is found in Caenorhabditis elegans. go-plus.json dosage compensation complex assembly during dosage compensation by hypoactivation of X chromosome http://purl.obolibrary.org/obo/GO_0042715 NCBITaxon:185431 biolink:OrganismalEntity Trypanosoma brucei brucei TREU927 go-plus.json Trypanosoma brucei strain TREU927|Trypanosoma brucei brucei strain 927/4 GUTat10.1|Trypanosoma brucei TREU927 http://purl.obolibrary.org/obo/NCBITaxon_185431 CHEBI:78451 biolink:ChemicalSubstance O-[S-(3R)-hydroxybutanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78451 chebi_ph7_3 GO:0042710 biolink:BiologicalProcess biofilm formation A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0042710 goslim_candida|gocheck_do_not_manually_annotate|gocheck_do_not_annotate|goslim_pir CHEBI:78450 biolink:ChemicalSubstance O-(S-acetoacetylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78450 chebi_ph7_3 CHEBI:136834 biolink:ChemicalSubstance 2-sulfenohercynine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136834 chebi_ph7_3 GO:0042712 biolink:BiologicalProcess paternal behavior Male behaviors associated with the care and rearing offspring. go-plus.json paternal behaviour http://purl.obolibrary.org/obo/GO_0042712 CHEBI:136833 biolink:ChemicalSubstance glycolaldehyde triphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136833 chebi_ph7_3 GO:0042711 biolink:BiologicalProcess maternal behavior Female behaviors associated with the care and rearing of offspring. go-plus.json maternal behaviour http://purl.obolibrary.org/obo/GO_0042711 CHEBI:30477 biolink:ChemicalSubstance tellurite go-plus.json http://purl.obolibrary.org/obo/CHEBI_30477 chebi_ph7_3 CHEBI:78455 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1)(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78455 chebi_ph7_3 CHEBI:78454 biolink:ChemicalSubstance O-(S-butanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78454 chebi_ph7_3 CHEBI:78453 biolink:ChemicalSubstance O-[S-(2E)-butenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78453 chebi_ph7_3 CHEBI:78452 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78452 chebi_ph7_3 UBERON:0007625 biolink:AnatomicalEntity pigment epithelium of eye epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules. go-plus.json eye pigment epithelium http://purl.obolibrary.org/obo/UBERON_0007625 CHEBI:78459 biolink:ChemicalSubstance O-(S-hexanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78459 chebi_ph7_3 GO:0042718 biolink:CellularComponent yolk granule Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed. go-plus.json http://purl.obolibrary.org/obo/GO_0042718 GO:0042717 biolink:CellularComponent plasma membrane-derived chromatophore membrane The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles. go-plus.json http://purl.obolibrary.org/obo/GO_0042717 CHEBI:78458 biolink:ChemicalSubstance O-[S-(2E)-hexenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78458 chebi_ph7_3 CHEBI:78457 biolink:ChemicalSubstance O-[S-(3R)-hydroxyhexanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78457 chebi_ph7_3 CHEBI:78456 biolink:ChemicalSubstance O-(S-3-oxohexanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78456 chebi_ph7_3 GO:0042719 biolink:CellularComponent mitochondrial intermembrane space protein transporter complex Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane. go-plus.json Tim9-Tim10 complex http://purl.obolibrary.org/obo/GO_0042719 CHEBI:30449 biolink:ChemicalSubstance validamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30449 CHEBI:29457 biolink:ChemicalSubstance (5Z,7E,9E,14Z,17Z)-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29457 GO:0042725 biolink:BiologicalProcess thiamine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it. go-plus.json thiamin and derivative catabolic process|thiamin and derivative catabolism|thiamine-containing compound catabolism|thiamine and derivative catabolism|vitamin B1 and derivative catabolism|thiamine-containing compound degradation|thiamin-containing compound catabolic process|thiamine-containing compound breakdown|vitamin B1 and derivative catabolic process|thiamine and derivative catabolic process http://purl.obolibrary.org/obo/GO_0042725 GO:0042724 biolink:BiologicalProcess thiamine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds. go-plus.json thiamine-containing compound anabolism|thiamine-containing compound synthesis|thiamin and derivative biosynthesis|thiamin and derivative biosynthetic process|thiamine-containing compound formation|thiamine-containing compound biosynthesis|thiamine and derivative biosynthetic process|thiamine and derivative biosynthesis|vitamin B1 and derivative biosynthetic process|vitamin B1 and derivative biosynthesis|thiamin-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0042724 GO:0042727 biolink:BiologicalProcess flavin-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. go-plus.json flavin-containing compound anabolism|flavin-containing compound synthesis|flavin-containing compound formation|flavin-containing compound biosynthesis|riboflavin and derivative biosynthetic process|riboflavin and derivative biosynthesis|vitamin B2 and derivative biosynthetic process|vitamin B2 and derivative biosynthesis http://purl.obolibrary.org/obo/GO_0042727 GO:0042726 biolink:BiologicalProcess flavin-containing compound metabolic process The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. go-plus.json flavin-containing compound metabolism|riboflavin and derivative metabolism|vitamin B2 and derivative metabolism|vitamin B2 and derivative metabolic process|riboflavin and derivative metabolic process http://purl.obolibrary.org/obo/GO_0042726 CHEBI:78462 biolink:ChemicalSubstance O-[S-(2E)-octenoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78462 chebi_ph7_3 GO:0042721 biolink:CellularComponent TIM22 mitochondrial import inner membrane insertion complex A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12. go-plus.json mitochondrial inner membrane protein insertion complex|mitochondrial protein translocase complex|Tim22 complex http://purl.obolibrary.org/obo/GO_0042721 UBERON:0007692 biolink:AnatomicalEntity nucleus of thalamus A nucleus of brain that is part of a thalamus. go-plus.json nuclear complex of thalamus|thalamic nucleus http://purl.obolibrary.org/obo/UBERON_0007692 GO:0042720 biolink:CellularComponent mitochondrial inner membrane peptidase complex Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space. go-plus.json IMP|mitochondrion inner membrane peptidase complex http://purl.obolibrary.org/obo/GO_0042720 CHEBI:78461 biolink:ChemicalSubstance O-[S-(3R)-hydroxyoctanoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78461 chebi_ph7_3 GO:0042723 biolink:BiologicalProcess thiamine-containing compound metabolic process The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it. go-plus.json thiamin and derivative metabolism|thiamine-containing compound metabolism|thiamin-containing compound metabolic process|thiamine and derivative metabolism|vitamin B1 and derivative metabolism|vitamin B1 and derivative metabolic process|thiamine and derivative metabolic process|thiamin and derivative metabolic process http://purl.obolibrary.org/obo/GO_0042723 CHEBI:78460 biolink:ChemicalSubstance O-(S-3-oxooctanoylpantetheine-4-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78460 chebi_ph7_3 UBERON:0007691 biolink:AnatomicalEntity gustatory pore The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project. go-plus.json taste pore|porus gustatorius http://purl.obolibrary.org/obo/UBERON_0007691 UBERON:0007690 biolink:AnatomicalEntity early pharyngeal endoderm . go-plus.json pharyngeal endoderm|pharyngeal region endoderm|early pharyngeal arch endoderm|pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0007690 GO:0042722 biolink:BiologicalProcess alpha-beta T cell activation by superantigen The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region. go-plus.json alpha-beta T-lymphocyte activation by superantigen|alpha-beta T-cell activation by superantigen|alpha-beta T lymphocyte activation by superantigen http://purl.obolibrary.org/obo/GO_0042722 CHEBI:78466 biolink:ChemicalSubstance O-[S-(3R)-hydroxydecanoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78466 chebi_ph7_3 CHEBI:78464 biolink:ChemicalSubstance O-(S-3-oxodecanoylpantetheine-4-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78464 chebi_ph7_3 CHEBI:78463 biolink:ChemicalSubstance O-(S-octanoylpantetheine-4-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78463 chebi_ph7_3 GO:0042729 biolink:CellularComponent DASH complex A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability. go-plus.json Duo1p-Dam1p-Dad1p complex|condensed nuclear chromosome kinetochore-associated DASH complex|DDD complex|Dam1 complex http://purl.obolibrary.org/obo/GO_0042729 CHEBI:78469 biolink:ChemicalSubstance O-(S-3-oxododecanoylpantetheine-4-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78469 chebi_ph7_3 GO:0042728 biolink:BiologicalProcess flavin-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. go-plus.json riboflavin and derivative catabolic process|flavin-containing compound catabolism|riboflavin and derivative catabolism|vitamin B2 and derivative catabolism|flavin-containing compound catabolic process degradation|flavin-containing compound catabolic process breakdown|vitamin B2 and derivative catabolic process http://purl.obolibrary.org/obo/GO_0042728 UBERON:0007699 biolink:AnatomicalEntity tract of spinal cord An axon tract that is part of a spinal cord. go-plus.json spinal cord tract http://purl.obolibrary.org/obo/UBERON_0007699 CHEBI:78468 biolink:ChemicalSubstance O-(S-decanoylpantetheine-4-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78468 chebi_ph7_3 CHEBI:78467 biolink:ChemicalSubstance O-[S-(2E)-decenoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78467 chebi_ph7_3 GO:0042730 biolink:BiologicalProcess fibrinolysis A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin. Wikipedia:Fibrinolysis go-plus.json http://purl.obolibrary.org/obo/GO_0042730 CHEBI:29461 biolink:ChemicalSubstance 10-deoxymethynolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29461 chebi_ph7_3 CHEBI:136819 biolink:ChemicalSubstance 5-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136819 GO:0042736 biolink:MolecularActivity NADH kinase activity Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH. KEGG_REACTION:R00105|EC:2.7.1.86|RHEA:12260|MetaCyc:NADH-KINASE-RXN go-plus.json DPNH kinase activity|reduced diphosphopyridine nucleotide kinase activity|reduced nicotinamide adenine dinucleotide kinase (phosphorylating)|ATP:NADH 2'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0042736 CHEBI:136810 biolink:ChemicalSubstance 12-hydroxyjasmonates go-plus.json http://purl.obolibrary.org/obo/CHEBI_136810 chebi_ph7_3 UBERON:0007685 biolink:AnatomicalEntity region of nephron tubule go-plus.json renal tubule region|region of renal tubule http://purl.obolibrary.org/obo/UBERON_0007685 GO:0042735 biolink:CellularComponent protein body A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0042735 UBERON:0007684 biolink:AnatomicalEntity uriniferous tubule functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007684 GO:0042738 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042738 GO:0042737 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042737 CHEBI:78473 biolink:ChemicalSubstance O-(S-3-oxotetradecanoylpantetheine-4-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78473 chebi_ph7_3 GO:0042732 biolink:BiologicalProcess D-xylose metabolic process The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide. go-plus.json D-xylose metabolism http://purl.obolibrary.org/obo/GO_0042732 GO:0042731 biolink:MolecularActivity PH domain binding Binding to a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0042731 CHEBI:136813 biolink:ChemicalSubstance 11-sulfojasmonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136813 chebi_ph7_3 CHEBI:78472 biolink:ChemicalSubstance O-[S-(2E)-dodecenoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78472 chebi_ph7_3 GO:0042734 biolink:CellularComponent presynaptic membrane A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. go-plus.json pre-synaptic membrane|presynaptic plasma membrane http://purl.obolibrary.org/obo/GO_0042734 goslim_synapse CHEBI:136812 biolink:ChemicalSubstance 11-hydroxyjasmonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136812 chebi_ph7_3 NCBITaxon:498846 biolink:OrganismalEntity Candidatus Korarchaeum cryptofilum go-plus.json Korarchaeum cryptofilum http://purl.obolibrary.org/obo/NCBITaxon_498846 GO:0042733 biolink:BiologicalProcess embryonic digit morphogenesis The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe. go-plus.json http://purl.obolibrary.org/obo/GO_0042733 CHEBI:136811 biolink:ChemicalSubstance 12-sulfojasmonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136811 chebi_ph7_3 CHEBI:78470 biolink:ChemicalSubstance O-[S-(3R)-hydroxydodecanoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78470 chebi_ph7_3 NCBITaxon:498845 biolink:OrganismalEntity Candidatus Korarchaeum go-plus.json Korarchaeum http://purl.obolibrary.org/obo/NCBITaxon_498845 CHEBI:78477 biolink:ChemicalSubstance O-(S-tetradecanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78477 chebi_ph7_3 CHEBI:78475 biolink:ChemicalSubstance O-[S-(2E)-tetradecenoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78475 chebi_ph7_3 CHEBI:78474 biolink:ChemicalSubstance O-[S-(3R)-hydroxytetradecanoylpantetheine-4-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78474 chebi_ph7_3 CHEBI:30452 biolink:ChemicalSubstance tellurium atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_30452 chebi_ph7_3 GO:0042739 biolink:BiologicalProcess obsolete endogenous drug catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism. go-plus.json endogenous drug degradation|endogenous drug breakdown|endogenous drug catabolism http://purl.obolibrary.org/obo/GO_0042739 UBERON:0007689 biolink:AnatomicalEntity thyroid diverticulum endodermal bud derived from the endodermal epithelium of the embryonic pharyngeal floor[MP]. The thyroid diverticulum is the embryological structure from which thyroid follicular cells derive. It grows from the floor of the pharnyx[WP]. go-plus.json saccus thyroideus|diverticulum thyroideum http://purl.obolibrary.org/obo/UBERON_0007689 UBERON:0007688 biolink:AnatomicalEntity anlage Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. go-plus.json future organ|field|organ field|developmental field http://purl.obolibrary.org/obo/UBERON_0007688 UBERON:0007687 biolink:AnatomicalEntity kidney field region of the embryo into the area in which the kidney rudiment will develop. go-plus.json kidney anlage http://purl.obolibrary.org/obo/UBERON_0007687 CHEBI:78478 biolink:ChemicalSubstance O-(S-3-oxohexadecanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78478 chebi_ph7_3 CHEBI:29438 biolink:ChemicalSubstance methanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29438 GO:0042741 biolink:BiologicalProcess endogenous antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism. go-plus.json endogenous antibiotic degradation|endogenous antibiotic breakdown|endogenous antibiotic catabolism http://purl.obolibrary.org/obo/GO_0042741 CHEBI:29435 biolink:ChemicalSubstance carbide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29435 GO:0042740 biolink:BiologicalProcess exogenous antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism. go-plus.json exogenous antibiotic catabolism|exogenous antibiotic degradation|exogenous antibiotic breakdown http://purl.obolibrary.org/obo/GO_0042740 CHEBI:29434 biolink:ChemicalSubstance carbide(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29434 GO:0042747 biolink:BiologicalProcess circadian sleep/wake cycle, REM sleep A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity. go-plus.json http://purl.obolibrary.org/obo/GO_0042747 CHEBI:78480 biolink:ChemicalSubstance O-[S-(3R)-hydroxyhexadecanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78480 chebi_ph7_3 GO:0042746 biolink:BiologicalProcess circadian sleep/wake cycle, wakefulness The part of the circadian sleep/wake cycle where the organism is not asleep. go-plus.json http://purl.obolibrary.org/obo/GO_0042746 GO:0042749 biolink:BiologicalProcess regulation of circadian sleep/wake cycle Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0042749 GO:0042748 biolink:BiologicalProcess circadian sleep/wake cycle, non-REM sleep All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions. go-plus.json http://purl.obolibrary.org/obo/GO_0042748 CHEBI:78484 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-stearoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78484 chebi_ph7_3 GO:0042743 biolink:BiologicalProcess hydrogen peroxide metabolic process The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. go-plus.json H2O2 metabolic process|hydrogen peroxide metabolism http://purl.obolibrary.org/obo/GO_0042743 CHEBI:78483 biolink:ChemicalSubstance O-(S-hexadecanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78483 chebi_ph7_3 GO:0042742 biolink:BiologicalProcess defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. go-plus.json defense response to bacterium, incompatible interaction|defense response to bacteria|resistance response to pathogenic bacterium|defence response to bacterium|resistance response to pathogenic bacteria|defence response to bacteria|antibacterial peptide activity http://purl.obolibrary.org/obo/GO_0042742 GO:0042745 biolink:BiologicalProcess circadian sleep/wake cycle The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. go-plus.json http://purl.obolibrary.org/obo/GO_0042745 CHEBI:78482 biolink:ChemicalSubstance N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78482 chebi_ph7_3 GO:0042744 biolink:BiologicalProcess hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2). go-plus.json hydrogen peroxide scavenging|hydrogen peroxide catabolism|hydrogen peroxide removal|hydrogen peroxide degradation|H2O2 scavenging|H2O2 catabolic process|detoxification of hydrogen peroxide|hydrogen peroxide breakdown|detoxification of H2O2 http://purl.obolibrary.org/obo/GO_0042744 CHEBI:78481 biolink:ChemicalSubstance O-[S-(2E)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78481 chebi_ph7_3 CHEBI:78488 biolink:ChemicalSubstance O-[S-(3R)-hydroxyoctadecanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78488 chebi_ph7_3 CHEBI:78487 biolink:ChemicalSubstance O-(S-3-oxooctadecanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78487 chebi_ph7_3 CHEBI:78486 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-stearoylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78486 chebi_ph7_3 CHEBI:78485 biolink:ChemicalSubstance ganglioside GM2 (18:0) (1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78485 chebi_ph7_3 CHEBI:78489 biolink:ChemicalSubstance O-[S-(2E)-octadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78489 chebi_ph7_3 CHEBI:30436 biolink:ChemicalSubstance tetrahydropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_30436 CHEBI:29449 biolink:ChemicalSubstance hydrogen azide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29449 GO:0042750 biolink:BiologicalProcess hibernation Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs. Wikipedia:Hibernation go-plus.json http://purl.obolibrary.org/obo/GO_0042750 GO:0042752 biolink:BiologicalProcess regulation of circadian rhythm Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. go-plus.json http://purl.obolibrary.org/obo/GO_0042752 GO:0042751 biolink:BiologicalProcess estivation Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season. Wikipedia:Estivation go-plus.json aestivation http://purl.obolibrary.org/obo/GO_0042751 GO:0042758 biolink:BiologicalProcess long-chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty acid with a chain length between C13 and C22. go-plus.json long-chain fatty acid breakdown|long-chain fatty acid catabolism|long-chain fatty acid degradation http://purl.obolibrary.org/obo/GO_0042758 GO:0042757 biolink:CellularComponent giant axon Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses. go-plus.json http://purl.obolibrary.org/obo/GO_0042757 GO:0042759 biolink:BiologicalProcess long-chain fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22. go-plus.json long-chain fatty acid anabolism|long-chain fatty acid synthesis|long-chain fatty acid formation|long-chain fatty acid biosynthesis http://purl.obolibrary.org/obo/GO_0042759 GO:0042754 biolink:BiologicalProcess negative regulation of circadian rhythm Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. go-plus.json downregulation of circadian rhythm|down regulation of circadian rhythm|inhibition of circadian rhythm|down-regulation of circadian rhythm http://purl.obolibrary.org/obo/GO_0042754 CHEBI:78495 biolink:ChemicalSubstance O-(S-octadecanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78495 chebi_ph7_3 GO:0042753 biolink:BiologicalProcess positive regulation of circadian rhythm Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior. go-plus.json upregulation of circadian rhythm|stimulation of circadian rhythm|up-regulation of circadian rhythm|activation of circadian rhythm|up regulation of circadian rhythm http://purl.obolibrary.org/obo/GO_0042753 CHEBI:78494 biolink:ChemicalSubstance 3'-(L-leucyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78494 chebi_ph7_3 GO:0042756 biolink:BiologicalProcess drinking behavior The specific behavior of an organism relating to the intake of liquids, especially water. go-plus.json drinking behaviour http://purl.obolibrary.org/obo/GO_0042756 GO:0042755 biolink:BiologicalProcess eating behavior The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. go-plus.json eating behaviour http://purl.obolibrary.org/obo/GO_0042755 CHEBI:78499 biolink:ChemicalSubstance C-terminal-gamma-L-glutamyl-L-2-aminoadipate 6-phosphate(4-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78499 chebi_ph7_3 CHEBI:78497 biolink:ChemicalSubstance 3'-(L-alanyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78497 chebi_ph7_3 GO:0003157 biolink:BiologicalProcess endocardium development The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go-plus.json http://purl.obolibrary.org/obo/GO_0003157 GO:0003156 biolink:BiologicalProcess regulation of animal organ formation Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. go-plus.json http://purl.obolibrary.org/obo/GO_0003156 GO:0003159 biolink:BiologicalProcess morphogenesis of an endothelium The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003159 GO:0003158 biolink:BiologicalProcess endothelium development The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003158 NCBITaxon:851 biolink:OrganismalEntity Fusobacterium nucleatum go-plus.json Fusiformis nucleatus|Corynebacterium fusiforme|Fusobacterium fusiforme|"Bacillus fusiformis" Veillon and Zuber 1898|Fusobacterium plauti-vincenti|Fusibacterium nucleatum|Fusiformis fusiformis http://purl.obolibrary.org/obo/NCBITaxon_851 GO:0003153 biolink:BiologicalProcess closure of embryonic heart tube Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold. go-plus.json http://purl.obolibrary.org/obo/GO_0003153 GO:0003152 biolink:BiologicalProcess morphogenesis of an epithelial fold involved in embryonic heart tube formation The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation. go-plus.json http://purl.obolibrary.org/obo/GO_0003152 GO:0003155 biolink:BiologicalProcess BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry. go-plus.json BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination http://purl.obolibrary.org/obo/GO_0003155 GO:0003154 biolink:BiologicalProcess BMP signaling pathway involved in determination of left/right symmetry A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry. go-plus.json BMP signaling pathway involved in determination of left/right asymmetry|BMP signalling pathway involved in determination of left/right symmetry http://purl.obolibrary.org/obo/GO_0003154 GO:0003151 biolink:BiologicalProcess outflow tract morphogenesis The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. go-plus.json http://purl.obolibrary.org/obo/GO_0003151 GO:0003150 biolink:BiologicalProcess muscular septum morphogenesis The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. go-plus.json http://purl.obolibrary.org/obo/GO_0003150 GO:0003168 biolink:BiologicalProcess Purkinje myocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. go-plus.json cardiac Purkinje fiber cell differentiation http://purl.obolibrary.org/obo/GO_0003168 GO:0003167 biolink:BiologicalProcess atrioventricular bundle cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers. go-plus.json AV bundle cell differentiation http://purl.obolibrary.org/obo/GO_0003167 GO:0003169 biolink:BiologicalProcess coronary vein morphogenesis The process in which the anatomical structures of veins of the heart are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003169 GO:0003164 biolink:BiologicalProcess His-Purkinje system development The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. go-plus.json http://purl.obolibrary.org/obo/GO_0003164 GO:0003163 biolink:BiologicalProcess sinoatrial node development The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. go-plus.json SAN development|SA node development|sinus node development http://purl.obolibrary.org/obo/GO_0003163 GO:0003166 biolink:BiologicalProcess bundle of His development The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers. go-plus.json atrioventricular bundle development http://purl.obolibrary.org/obo/GO_0003166 GO:0003165 biolink:BiologicalProcess Purkinje myocyte development The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. go-plus.json cardiac Purkinje fiber development http://purl.obolibrary.org/obo/GO_0003165 GO:0003160 biolink:BiologicalProcess endocardium morphogenesis The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. go-plus.json http://purl.obolibrary.org/obo/GO_0003160 GO:0003162 biolink:BiologicalProcess atrioventricular node development The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. go-plus.json AV node development http://purl.obolibrary.org/obo/GO_0003162 GO:0003161 biolink:BiologicalProcess cardiac conduction system development The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. go-plus.json heart conduction system development|cardiac impulse conducting system development http://purl.obolibrary.org/obo/GO_0003161 GO:0003139 biolink:BiologicalProcess secondary heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). go-plus.json SHF specification|anterior heart field specification|second heart field specification http://purl.obolibrary.org/obo/GO_0003139 GO:0003138 biolink:BiologicalProcess primary heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. go-plus.json FHS specification|first heart field specification http://purl.obolibrary.org/obo/GO_0003138 GO:0003135 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in heart induction The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction. go-plus.json fibroblast growth factor receptor signalling pathway involved in heart induction http://purl.obolibrary.org/obo/GO_0003135 GO:0003134 biolink:BiologicalProcess endodermal-mesodermal cell signaling involved in heart induction Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction. go-plus.json endodermal-mesodermal cell signalling involved in heart induction http://purl.obolibrary.org/obo/GO_0003134 GO:0003137 biolink:BiologicalProcess Notch signaling pathway involved in heart induction The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. go-plus.json Notch signalling pathway involved in heart induction http://purl.obolibrary.org/obo/GO_0003137 GO:0003136 biolink:BiologicalProcess negative regulation of heart induction by canonical Wnt signaling pathway Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction. go-plus.json negative regulation of cardioblast cell fate specification by Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt receptor signalling pathway|negative regulation of heart induction by canonical Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt-activated signaling pathway http://purl.obolibrary.org/obo/GO_0003136 GO:0003131 biolink:BiologicalProcess mesodermal-endodermal cell signaling Any process that mediates the transfer of information from mesodermal cells to endodermal cells. go-plus.json mesodermal-endodermal cell signalling http://purl.obolibrary.org/obo/GO_0003131 GO:0003130 biolink:BiologicalProcess BMP signaling pathway involved in heart induction A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to heart induction. go-plus.json BMP signalling pathway involved in heart induction http://purl.obolibrary.org/obo/GO_0003130 GO:0003133 biolink:BiologicalProcess endodermal-mesodermal cell signaling Any process that mediates the transfer of information from endodermal cells to mesodermal cells. go-plus.json endodermal-mesodermal cell signalling http://purl.obolibrary.org/obo/GO_0003133 GO:0003132 biolink:BiologicalProcess mesodermal-endodermal cell signaling involved in heart induction Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction. go-plus.json mesodermal-endodermal cell signalling involved in heart induction http://purl.obolibrary.org/obo/GO_0003132 GO:0003149 biolink:BiologicalProcess membranous septum morphogenesis The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. go-plus.json http://purl.obolibrary.org/obo/GO_0003149 GO:0003146 biolink:BiologicalProcess heart jogging The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis. go-plus.json cardiac jogging http://purl.obolibrary.org/obo/GO_0003146 GO:0003145 biolink:BiologicalProcess embryonic heart tube formation via epithelial folding The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis. go-plus.json http://purl.obolibrary.org/obo/GO_0003145 GO:0003148 biolink:BiologicalProcess outflow tract septum morphogenesis The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. go-plus.json http://purl.obolibrary.org/obo/GO_0003148 GO:0003147 biolink:BiologicalProcess neural crest cell migration involved in heart formation The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. go-plus.json http://purl.obolibrary.org/obo/GO_0003147 GO:0003142 biolink:BiologicalProcess cardiogenic plate morphogenesis The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. go-plus.json cardiac crescent morphogenesis http://purl.obolibrary.org/obo/GO_0003142 GO:0003141 biolink:BiologicalProcess obsolete transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry OBSOLETE. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to lateral mesoderm left/right asymmetry determination. go-plus.json transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signaling pathway involved in lateral mesoderm left/right asymmetry determination http://purl.obolibrary.org/obo/GO_0003141 GO:0003144 biolink:BiologicalProcess embryonic heart tube formation The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003144 GO:0003143 biolink:BiologicalProcess embryonic heart tube morphogenesis The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003143 GO:0003140 biolink:BiologicalProcess determination of left/right asymmetry in lateral mesoderm The establishment of the lateral mesoderm with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0003140 GO:0003117 biolink:BiologicalProcess regulation of vasoconstriction by circulating norepinephrine Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream. go-plus.json regulation of vasoconstriction by circulating noradrenaline http://purl.obolibrary.org/obo/GO_0003117 GO:0003116 biolink:BiologicalProcess regulation of vasoconstriction by norepinephrine Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings. go-plus.json http://purl.obolibrary.org/obo/GO_0003116 GO:0003119 biolink:BiologicalProcess regulation of vasoconstriction by neuronal epinephrine Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings. go-plus.json regulation of vasoconstriction by neuronal adrenaline http://purl.obolibrary.org/obo/GO_0003119 GO:0003118 biolink:BiologicalProcess regulation of vasoconstriction by neuronal norepinephrine Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings. go-plus.json regulation of vasoconstriction by neuronal noradrenaline http://purl.obolibrary.org/obo/GO_0003118 GO:0003113 biolink:BiologicalProcess positive regulation of heart rate by neuronal norepinephrine The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction. go-plus.json positive regulation of heart rate by neuronal noradrenaline http://purl.obolibrary.org/obo/GO_0003113 GO:0003112 biolink:BiologicalProcess positive regulation of heart rate by neuronal epinephrine The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction. go-plus.json positive regulation of heart rate by neuronal adrenaline http://purl.obolibrary.org/obo/GO_0003112 GO:0003115 biolink:BiologicalProcess regulation of vasoconstriction by epinephrine Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings. go-plus.json http://purl.obolibrary.org/obo/GO_0003115 GO:0003114 biolink:BiologicalProcess positive regulation of heart rate by circulating norepinephrine The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction. go-plus.json positive regulation of heart rate by circulating noradrenaline http://purl.obolibrary.org/obo/GO_0003114 GO:0003111 biolink:BiologicalProcess positive regulation of heart rate by circulating epinephrine The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction. go-plus.json positive regulation of heart rate by circulating adrenaline http://purl.obolibrary.org/obo/GO_0003111 GO:0003110 biolink:BiologicalProcess positive regulation of the force of heart contraction by neuronal norepinephrine The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction. go-plus.json increased force of heart contraction by neuronal noradrenaline|increased force of heart contraction by neuronal norepinephrine http://purl.obolibrary.org/obo/GO_0003110 CHEBI:136887 biolink:ChemicalSubstance nickel-sirohydrochlorin a,c-diamide(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136887 chebi_ph7_3 CHEBI:136886 biolink:ChemicalSubstance 16-epiestriol 16-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136886 chebi_ph7_3 CHEBI:136885 biolink:ChemicalSubstance 16-epiestriol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136885 chebi_ph7_3 CHEBI:136884 biolink:ChemicalSubstance 17-epiestriol 16-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136884 chebi_ph7_3 CHEBI:136889 biolink:ChemicalSubstance 5beta steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136889 CHEBI:136888 biolink:ChemicalSubstance 15,17(3)-seco-F430-17(3)-acid(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136888 chebi_ph7_3 UBERON:0007617 biolink:AnatomicalEntity synovial cavity of joint An anatomical cavity that surrounded_by a synovial joint. go-plus.json cavitas articularis (junctura synovialis)|cavity of synovial joint|synovial cavity|joint cavity|articular cavity (synovial joint) http://purl.obolibrary.org/obo/UBERON_0007617 UBERON:0007616 biolink:AnatomicalEntity layer of synovial tissue A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]. go-plus.json synovial membrane|synovium|stratum synoviale|synovial layer|synovial tissue http://purl.obolibrary.org/obo/UBERON_0007616 CHEBI:136883 biolink:ChemicalSubstance 17-epiestriol 17-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136883 chebi_ph7_3 CHEBI:136882 biolink:ChemicalSubstance 17-epiestriol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136882 chebi_ph7_3 CHEBI:136881 biolink:ChemicalSubstance 3-carboxy-3-hydroxypropanoyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136881 chebi_ph7_3 GO:0003128 biolink:BiologicalProcess heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop. go-plus.json http://purl.obolibrary.org/obo/GO_0003128 GO:0003127 biolink:BiologicalProcess detection of nodal flow The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry. go-plus.json http://purl.obolibrary.org/obo/GO_0003127 GO:0003129 biolink:BiologicalProcess heart induction The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003129 GO:0003124 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003124 GO:0003123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003123 GO:0003126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003126 GO:0003125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003125 GO:0003120 biolink:BiologicalProcess regulation of vasoconstriction by circulating epinephrine Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream. go-plus.json regulation of vasoconstriction by circulating adrenaline http://purl.obolibrary.org/obo/GO_0003120 GO:0003122 biolink:BiologicalProcess norepinephrine-mediated vasodilation A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings. go-plus.json regulation of vasodilation by circulating noradrenaline|regulation of vasodilation by noradrenaline|regulation of vasodilation by neuronal noradrenaline|regulation of vasodilation by neuronal norepinephrine|regulation of vasodilation by norepinephrine|regulation of vasodilation by circulating norepinephrine http://purl.obolibrary.org/obo/GO_0003122 GO:0003121 biolink:BiologicalProcess epinephrine-mediated vasodilation A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings. go-plus.json regulation of vasodilation by neuronal adrenaline|regulation of vasodilation by adrenaline|regulation of vasodilation by circulating adrenaline|regulation of vasodilation by circulating epinephrine|regulation of vasodilation by epinephrine|regulation of vasodilation by neuronal epinephrine http://purl.obolibrary.org/obo/GO_0003121 CHEBI:136897 biolink:ChemicalSubstance O-[S-(3S)-hydroxy-3-methylglutarylpantetheine-4'-phosphoryl]-L-serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136897 chebi_ph7_3 CHEBI:136896 biolink:ChemicalSubstance 5'-(5'-triphosphoguanosine)-(purine-ribonucleotide)(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136896 chebi_ph7_3 CHEBI:136895 biolink:ChemicalSubstance dTDP-L-rhamnose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136895 chebi_ph7_3 CHEBI:136899 biolink:ChemicalSubstance chenodeoxycholic acid 24-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136899 chebi_ph7_3 CHEBI:136890 biolink:ChemicalSubstance 3-dimethylallyl-4-hydroxymandelate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136890 chebi_ph7_3 UBERON:0007601 biolink:AnatomicalEntity ciliated epithelium Epithelium bearing vibratile cilia on the free surface. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007601 CHEBI:136891 biolink:ChemicalSubstance 2'-unsubstituted isoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_136891 chebi_ph7_3 NCBITaxon:112509 biolink:OrganismalEntity Hordeum vulgare subsp. vulgare go-plus.json Hordeum sativum|Hordeum vulgare var. vulgare|domesticated barley|Hordeum vulgare var. nudum|two-rowed barley http://purl.obolibrary.org/obo/NCBITaxon_112509 CHEBI:136860 biolink:ChemicalSubstance antidote to sarin poisoning go-plus.json http://purl.obolibrary.org/obo/CHEBI_136860 CHEBI:78402 biolink:ChemicalSubstance 1-oleyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78402 chebi_ph7_3 CHEBI:78419 biolink:ChemicalSubstance 1-(Z)-alk-1-enyl-2-acetyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78419 chebi_ph7_3 GO:0003106 biolink:BiologicalProcess negative regulation of glomerular filtration by angiotensin The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. go-plus.json angiotensin-mediated regulation of glomerular filtration|regulation of glomerular filtration by angiotensin http://purl.obolibrary.org/obo/GO_0003106 GO:0003105 biolink:BiologicalProcess negative regulation of glomerular filtration Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0003105 GO:0003108 biolink:BiologicalProcess negative regulation of the force of heart contraction by chemical signal Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. go-plus.json negative regulation of the force of heart muscle contraction by chemical signal http://purl.obolibrary.org/obo/GO_0003108 GO:0003107 biolink:BiologicalProcess obsolete positive regulation of natriuresis by angiotensin OBSOLETE. The process in which angiotensin increases the rate of natriuresis indirectly via diuresis. Natriuresis is the process of renal sodium excretion. go-plus.json positive regulation of natriuresis by angiotensin|angiotensin-mediated positive regulation of natriuresis http://purl.obolibrary.org/obo/GO_0003107 GO:0003102 biolink:BiologicalProcess obsolete positive regulation of diuresis by angiotensin OBSOLETE. Any process mediated by angiotensin that increases the rate of diuresis. go-plus.json angiotensin-mediated positive regulation of diuresis|positive regulation of diuresis by angiotensin http://purl.obolibrary.org/obo/GO_0003102 GO:0003101 biolink:BiologicalProcess regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system. go-plus.json regulation of blood pressure by circulating adrenaline-noradrenaline http://purl.obolibrary.org/obo/GO_0003101 GO:0003104 biolink:BiologicalProcess positive regulation of glomerular filtration Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. go-plus.json http://purl.obolibrary.org/obo/GO_0003104 GO:0003103 biolink:BiologicalProcess obsolete positive regulation of diuresis OBSOLETE. Any process that activates or increases the frequency, rate or extent of diuresis. Diuresis is the process of renal water excretion. go-plus.json positive regulation of diuresis http://purl.obolibrary.org/obo/GO_0003103 GO:0003100 biolink:BiologicalProcess regulation of systemic arterial blood pressure by endothelin The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor. go-plus.json http://purl.obolibrary.org/obo/GO_0003100 CHEBI:136876 biolink:ChemicalSubstance 1-(3,4-dihydroxybenzoyl)-beta-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_136876 chebi_ph7_3 CHEBI:136875 biolink:ChemicalSubstance oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136875 chebi_ph7_3 CHEBI:136873 biolink:ChemicalSubstance oligoglycosyl-(1->4)-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_136873 chebi_ph7_3 CHEBI:136879 biolink:ChemicalSubstance 5-(carboxymethoxy)uridine 5'-phosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136879 chebi_ph7_3 CHEBI:136878 biolink:ChemicalSubstance C2-C8-saturated long-chain fatty acyl pantetheine-4-phosphorylserine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136878 chebi_ph7_3 CHEBI:136877 biolink:ChemicalSubstance 5-hydroxyuridine 5'-phosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136877 chebi_ph7_3 CHEBI:78415 biolink:ChemicalSubstance trioxilin anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78415 GO:0003109 biolink:BiologicalProcess positive regulation of the force of heart contraction by circulating norepinephrine The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction. go-plus.json increased force of heart contraction by circulating norepinephrine|increased force of heart contraction by circulating noradrenaline http://purl.obolibrary.org/obo/GO_0003109 GO:1904039 biolink:BiologicalProcess negative regulation of iron export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json down-regulation of iron(2+) export|downregulation of ferrous iron export|negative regulation of ferrous iron export|down-regulation of ferrous iron export|inhibition of iron(2+) export|negative regulation of iron(2+) export|down regulation of iron(2+) export|inhibition of ferrous iron export|downregulation of iron(2+) export|down regulation of ferrous iron export http://purl.obolibrary.org/obo/GO_1904039 GO:1904038 biolink:BiologicalProcess regulation of iron export across plasma membrane Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json regulation of iron(2+) export|regulation of ferrous iron export http://purl.obolibrary.org/obo/GO_1904038 GO:1904037 biolink:BiologicalProcess positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process. go-plus.json upregulation of epithelial cell apoptotic process|upregulation of epitheliocyte apoptotic process|up regulation of epithelial cell apoptosis|up regulation of epitheliocyte apoptosis|positive regulation of epithelial cell apoptosis|positive regulation of epitheliocyte apoptosis|up regulation of epithelial cell apoptotic process|activation of epithelial cell apoptotic process|up regulation of epitheliocyte apoptotic process|activation of epithelial cell apoptosis|activation of epitheliocyte apoptotic process|activation of epitheliocyte apoptosis|positive regulation of epitheliocyte apoptotic process|up-regulation of epithelial cell apoptosis|up-regulation of epitheliocyte apoptosis|up-regulation of epithelial cell apoptotic process|up-regulation of epitheliocyte apoptotic process|upregulation of epithelial cell apoptosis|upregulation of epitheliocyte apoptosis http://purl.obolibrary.org/obo/GO_1904037 GO:1904036 biolink:BiologicalProcess negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process. go-plus.json down regulation of epitheliocyte apoptosis|downregulation of epithelial cell apoptosis|downregulation of epitheliocyte apoptosis|down regulation of epithelial cell apoptotic process|down regulation of epitheliocyte apoptotic process|downregulation of epithelial cell apoptotic process|downregulation of epitheliocyte apoptotic process|down-regulation of epithelial cell apoptosis|negative regulation of epithelial cell apoptosis|negative regulation of epitheliocyte apoptosis|down-regulation of epitheliocyte apoptosis|down-regulation of epithelial cell apoptotic process|down-regulation of epitheliocyte apoptotic process|negative regulation of epitheliocyte apoptotic process|inhibition of epithelial cell apoptosis|inhibition of epithelial cell apoptotic process|inhibition of epitheliocyte apoptosis|inhibition of epitheliocyte apoptotic process|down regulation of epithelial cell apoptosis http://purl.obolibrary.org/obo/GO_1904036 GO:1904046 biolink:BiologicalProcess negative regulation of vascular endothelial growth factor production Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production. go-plus.json down regulation of VEGF production|down regulation of vascular endothelial growth factor production|downregulation of VEGF production|downregulation of vascular endothelial growth factor production|negative regulation of VEGF production|down-regulation of VEGF production|down-regulation of vascular endothelial growth factor production|inhibition of VEGF production|inhibition of vascular endothelial growth factor production http://purl.obolibrary.org/obo/GO_1904046 GO:1904045 biolink:BiologicalProcess cellular response to aldosterone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904045 GO:1904044 biolink:BiologicalProcess response to aldosterone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904044 GO:1904043 biolink:BiologicalProcess positive regulation of cystathionine beta-synthase activity Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity. go-plus.json up regulation of L-serine hydro-lyase (adding homocysteine)|up regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up-regulation of beta-thionase activity|upregulation of methylcysteine synthase activity|activation of beta-thionase activity|activation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|positive regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|upregulation of cystathionine beta-synthase activity|up-regulation of serine sulfhydrase activity|up regulation of serine sulfhydrylase activity|activation of serine sulfhydrylase activity|positive regulation of serine sulfhydrylase activity|upregulation of L-serine hydro-lyase (adding homocysteine)|up-regulation of methylcysteine synthase activity|positive regulation of beta-thionase activity|activation of methylcysteine synthase activity|up-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of beta-thionase activity|up-regulation of cystathionine beta-synthase activity|activation of cystathionine beta-synthase activity|upregulation of serine sulfhydrase activity|up-regulation of L-serine hydro-lyase (adding homocysteine)|activation of L-serine hydro-lyase (adding homocysteine)|up-regulation of serine sulfhydrylase activity|positive regulation of methylcysteine synthase activity|upregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of methylcysteine synthase activity|upregulation of beta-thionase activity|up regulation of serine sulfhydrase activity|activation of serine sulfhydrase activity|positive regulation of serine sulfhydrase activity|up regulation of cystathionine beta-synthase activity|upregulation of serine sulfhydrylase activity|positive regulation of L-serine hydro-lyase (adding homocysteine) http://purl.obolibrary.org/obo/GO_1904043 GO:1904042 biolink:BiologicalProcess negative regulation of cystathionine beta-synthase activity Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity. go-plus.json inhibition of methylcysteine synthase activity|down regulation of cystathionine beta-synthase activity|downregulation of L-serine hydro-lyase (adding homocysteine)|downregulation of serine sulfhydrylase activity|inhibition of cystathionine beta-synthase activity|negative regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|inhibition of serine sulfhydrase activity|down-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of L-serine hydro-lyase (adding homocysteine)|negative regulation of beta-thionase activity|down-regulation of beta-thionase activity|inhibition of L-serine hydro-lyase (adding homocysteine)|negative regulation of serine sulfhydrylase activity|down-regulation of serine sulfhydrylase activity|inhibition of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|downregulation of beta-thionase activity|down-regulation of methylcysteine synthase activity|negative regulation of methylcysteine synthase activity|down regulation of serine sulfhydrase activity|inhibition of serine sulfhydrylase activity|down regulation of beta-thionase activity|down-regulation of cystathionine beta-synthase activity|inhibition of beta-thionase activity|downregulation of serine sulfhydrase activity|negative regulation of L-serine hydro-lyase (adding homocysteine)|down-regulation of L-serine hydro-lyase (adding homocysteine)|down regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|downregulation of methylcysteine synthase activity|downregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of methylcysteine synthase activity|downregulation of cystathionine beta-synthase activity|down-regulation of serine sulfhydrase activity|negative regulation of serine sulfhydrase activity|down regulation of serine sulfhydrylase activity http://purl.obolibrary.org/obo/GO_1904042 GO:0052281 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052281 GO:1904041 biolink:BiologicalProcess regulation of cystathionine beta-synthase activity Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity. go-plus.json regulation of serine sulfhydrylase activity|regulation of L-serine hydro-lyase (adding homocysteine)|regulation of beta-thionase activity|regulation of serine sulfhydrase activity|regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|regulation of methylcysteine synthase activity http://purl.obolibrary.org/obo/GO_1904041 GO:0052280 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052280 GO:1904040 biolink:BiologicalProcess positive regulation of iron export across plasma membrane Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json up regulation of iron(2+) export|upregulation of ferrous iron export|activation of iron(2+) export|up regulation of ferrous iron export|positive regulation of ferrous iron export|up-regulation of iron(2+) export|activation of ferrous iron export|positive regulation of iron(2+) export|upregulation of iron(2+) export|up-regulation of ferrous iron export http://purl.obolibrary.org/obo/GO_1904040 GO:0052285 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052285 GO:0052284 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052284 GO:0052283 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052283 GO:0052282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052282 GO:0052289 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052289 GO:0052288 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052288 GO:0052287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052287 GO:0052286 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052286 GO:1904049 biolink:BiologicalProcess negative regulation of spontaneous neurotransmitter secretion Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion. go-plus.json down regulation of stimulus-independent neurotransmitter secretion|downregulation of spontaneous neurotransmitter secretion|down regulation of spontaneous neurotransmitter secretion|downregulation of stimulus-independent neurotransmitter secretion|inhibition of spontaneous neurotransmitter secretion|down-regulation of stimulus-independent neurotransmitter secretion|negative regulation of stimulus-independent neurotransmitter secretion|inhibition of stimulus-independent neurotransmitter secretion|down-regulation of spontaneous neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1904049 GO:1904048 biolink:BiologicalProcess regulation of spontaneous neurotransmitter secretion Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion. go-plus.json regulation of stimulus-independent neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1904048 GO:1904047 biolink:MolecularActivity S-adenosyl-L-methionine binding Binding to S-adenosyl-L-methionine. Reactome:R-HSA-947535 go-plus.json radical SAM enzyme activity http://purl.obolibrary.org/obo/GO_1904047 GO:1904057 biolink:BiologicalProcess negative regulation of sensory perception of pain Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. go-plus.json downregulation of nociception|down-regulation of sensory perception of pain|inhibition of perception of physiological pain|down-regulation of nociception|negative regulation of nociception|downregulation of sensory perception of pain|negative regulation of perception of physiological pain|inhibition of nociception|down-regulation of perception of physiological pain|down regulation of sensory perception of pain|inhibition of sensory perception of pain|downregulation of perception of physiological pain|down regulation of nociception|down regulation of perception of physiological pain http://purl.obolibrary.org/obo/GO_1904057 GO:1904056 biolink:BiologicalProcess positive regulation of cholangiocyte proliferation Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation. go-plus.json up regulation of hepatoblast proliferation|upregulation of cholangiocyte proliferation|activation of hepatoblast proliferation|positive regulation of hepatoblast proliferation|up regulation of cholangiocyte proliferation|activation of cholangiocyte proliferation|up-regulation of hepatoblast proliferation|upregulation of hepatoblast proliferation|up-regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_1904056 GO:1904055 biolink:BiologicalProcess negative regulation of cholangiocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation. go-plus.json downregulation of hepatoblast proliferation|down regulation of cholangiocyte proliferation|down-regulation of hepatoblast proliferation|negative regulation of hepatoblast proliferation|downregulation of cholangiocyte proliferation|inhibition of hepatoblast proliferation|down-regulation of cholangiocyte proliferation|inhibition of cholangiocyte proliferation|down regulation of hepatoblast proliferation http://purl.obolibrary.org/obo/GO_1904055 GO:1904054 biolink:BiologicalProcess regulation of cholangiocyte proliferation Any process that modulates the frequency, rate or extent of cholangiocyte proliferation. go-plus.json regulation of hepatoblast proliferation http://purl.obolibrary.org/obo/GO_1904054 GO:1904053 biolink:BiologicalProcess positive regulation of protein targeting to vacuole involved in autophagy Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy. go-plus.json up-regulation of protein targeting to vacuole involved in autophagy|activation of protein targeting to vacuole involved in autophagy|up regulation of protein targeting to vacuole involved in autophagy|upregulation of protein targeting to vacuole involved in autophagy http://purl.obolibrary.org/obo/GO_1904053 GO:0052292 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052292 GO:1904052 biolink:BiologicalProcess negative regulation of protein targeting to vacuole involved in autophagy Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy. go-plus.json down-regulation of protein targeting to vacuole involved in autophagy|downregulation of protein targeting to vacuole involved in autophagy|down regulation of protein targeting to vacuole involved in autophagy|inhibition of protein targeting to vacuole involved in autophagy http://purl.obolibrary.org/obo/GO_1904052 GO:0052291 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052291 GO:1904051 biolink:BiologicalProcess regulation of protein targeting to vacuole involved in autophagy Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy. go-plus.json http://purl.obolibrary.org/obo/GO_1904051 GO:0052290 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052290 GO:1904050 biolink:BiologicalProcess positive regulation of spontaneous neurotransmitter secretion Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion. go-plus.json activation of spontaneous neurotransmitter secretion|up-regulation of spontaneous neurotransmitter secretion|up-regulation of stimulus-independent neurotransmitter secretion|up regulation of spontaneous neurotransmitter secretion|upregulation of stimulus-independent neurotransmitter secretion|up regulation of stimulus-independent neurotransmitter secretion|upregulation of spontaneous neurotransmitter secretion|activation of stimulus-independent neurotransmitter secretion|positive regulation of stimulus-independent neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1904050 GO:0052296 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052296 GO:0052295 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052295 GO:0052294 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052294 GO:0052293 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052293 GO:0052299 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052299 GO:0052298 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052298 GO:0052297 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052297 GO:1904059 biolink:BiologicalProcess regulation of locomotor rhythm Any process that modulates the frequency, rate or extent of locomotor rhythm. go-plus.json regulation of circadian locomotor activity rhythm http://purl.obolibrary.org/obo/GO_1904059 GO:1904058 biolink:BiologicalProcess positive regulation of sensory perception of pain Any process that activates or increases the frequency, rate or extent of sensory perception of pain. go-plus.json activation of sensory perception of pain|upregulation of perception of physiological pain|up regulation of nociception|positive regulation of nociception|activation of nociception|up regulation of sensory perception of pain|up-regulation of perception of physiological pain|activation of perception of physiological pain|up-regulation of nociception|upregulation of sensory perception of pain|positive regulation of perception of physiological pain|up regulation of perception of physiological pain|upregulation of nociception|up-regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_1904058 GO:1904068 biolink:BiologicalProcess G protein-coupled receptor signaling pathway involved in social behavior Any G protein-coupled receptor signaling pathway that is involved in social behavior. go-plus.json G protein coupled receptor protein signaling pathway involved in social behaviour|G-protein coupled receptor signalling pathway involved in cooperative behavior|G-protein coupled receptor protein signal transduction involved in social behavior|G protein coupled receptor protein signalling pathway involved in social behaviour|G-protein-coupled receptor protein signaling pathway involved in cooperative behavior|GPCR signalling pathway involved in cooperative behavior|GPCR signalling pathway involved in social behavior|G-protein-coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor signaling pathway involved in social behavior|G-protein coupled receptor signalling pathway involved in social behavior|GPCR signaling pathway involved in social behaviour|G-protein coupled receptor protein signal transduction involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in social behaviour|G protein coupled receptor protein signaling pathway involved in cooperative behavior|G protein coupled receptor protein signalling pathway involved in cooperative behavior|G-protein coupled receptor signaling pathway involved in social behaviour|G-protein coupled receptor protein signaling pathway involved in social behaviour|GPCR signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in cooperative behavior|G-protein coupled receptor signaling pathway involved in cooperative behavior|G-protein coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor protein signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in social behavior|GPCR signaling pathway involved in social behavior|G-protein coupled receptor signalling pathway involved in social behaviour|G-protein-coupled receptor protein signaling pathway involved in social behaviour|GPCR signalling pathway involved in social behaviour|G protein coupled receptor protein signalling pathway involved in social behavior|G protein coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor protein signal transduction involved in social behaviour http://purl.obolibrary.org/obo/GO_1904068 GO:1904067 biolink:MolecularActivity ascr#2 binding Binding to ascr#2. go-plus.json http://purl.obolibrary.org/obo/GO_1904067 GO:1904066 biolink:BiologicalProcess G protein-coupled receptor signaling pathway involved in dauer larval development Any G protein-coupled receptor signaling pathway that is involved in dauer larval development. go-plus.json G-protein coupled receptor signalling pathway involved in dauer larval development|GPCR signalling pathway involved in dauer larval development|G-protein coupled receptor protein signal transduction involved in dauer larval development|G protein coupled receptor protein signaling pathway involved in dauer larval development|G protein coupled receptor protein signalling pathway involved in dauer larval development|GPCR signaling pathway involved in dauer larval development|G-protein-coupled receptor protein signalling pathway involved in dauer larval development|G-protein coupled receptor protein signaling pathway involved in dauer larval development http://purl.obolibrary.org/obo/GO_1904066 GO:1904065 biolink:BiologicalProcess G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission. go-plus.json acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission|G-protein coupled acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|acetylcholine receptor signalling, muscarinic pathway involved in up-regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|acetylcholine receptor signalling, muscarinic pathway involved in upregulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in up regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion http://purl.obolibrary.org/obo/GO_1904065 GO:1904064 biolink:BiologicalProcess positive regulation of cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation transmembrane transport. go-plus.json up regulation of cation transmembrane transport|upregulation of cation transmembrane transport|activation of cation transmembrane transport|up-regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904064 GO:1904063 biolink:BiologicalProcess negative regulation of cation transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport. go-plus.json down-regulation of cation transmembrane transport|downregulation of cation transmembrane transport|down regulation of cation transmembrane transport|inhibition of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904063 GO:1904062 biolink:BiologicalProcess regulation of cation transmembrane transport Any process that modulates the frequency, rate or extent of cation transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1904062 GO:1904061 biolink:BiologicalProcess positive regulation of locomotor rhythm Any process that activates or increases the frequency, rate or extent of locomotor rhythm. go-plus.json activation of locomotor rhythm|positive regulation of circadian locomotor activity rhythm|activation of circadian locomotor activity rhythm|up-regulation of circadian locomotor activity rhythm|up regulation of locomotor rhythm|upregulation of circadian locomotor activity rhythm|upregulation of locomotor rhythm|up regulation of circadian locomotor activity rhythm|up-regulation of locomotor rhythm http://purl.obolibrary.org/obo/GO_1904061 GO:1904060 biolink:BiologicalProcess negative regulation of locomotor rhythm Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm. go-plus.json negative regulation of circadian locomotor activity rhythm|down-regulation of circadian locomotor activity rhythm|down-regulation of locomotor rhythm|inhibition of circadian locomotor activity rhythm|downregulation of locomotor rhythm|down regulation of locomotor rhythm|inhibition of locomotor rhythm|down regulation of circadian locomotor activity rhythm|downregulation of circadian locomotor activity rhythm http://purl.obolibrary.org/obo/GO_1904060 GO:1904069 biolink:BiologicalProcess ascaroside metabolic process The chemical reactions and pathways involving ascaroside. go-plus.json ascaroside metabolism http://purl.obolibrary.org/obo/GO_1904069 GO:1904079 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in negative regulation of neuron apoptotic process. go-plus.json inhibition of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in down regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in downregulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|inhibition of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in neuron survival|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in inhibition of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in neuron survival|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in neuron survival|down-regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in neuron survival|down-regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in down-regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|downregulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in inhibition of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in down-regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|inhibition of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|inhibition of global transcription from RNA polymerase II promoter involved in neuron survival|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from Pol II promoter involved in downregulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons http://purl.obolibrary.org/obo/GO_1904079 GO:1904078 biolink:BiologicalProcess positive regulation of estrogen biosynthetic process Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process. go-plus.json positive regulation of estrogen biosynthesis|activation of estrogen synthesis|activation of estrogen biosynthesis|activation of estrogen biosynthetic process|up-regulation of estrogen formation|activation of estrogen formation|positive regulation of estrogen anabolism|upregulation of oestrogen biosynthesis|upregulation of oestrogen biosynthetic process|up regulation of estrogen anabolism|positive regulation of estrogen synthesis|up-regulation of estrogen biosynthetic process|up-regulation of estrogen biosynthesis|up regulation of estrogen synthesis|positive regulation of estrogen formation|up regulation of estrogen formation|up-regulation of oestrogen biosynthesis|up-regulation of oestrogen biosynthetic process|activation of oestrogen biosynthesis|activation of oestrogen biosynthetic process|upregulation of estrogen anabolism|upregulation of estrogen biosynthesis|upregulation of estrogen biosynthetic process|upregulation of estrogen synthesis|upregulation of estrogen formation|up-regulation of estrogen anabolism|positive regulation of oestrogen biosynthetic process|positive regulation of oestrogen biosynthesis|activation of estrogen anabolism|up regulation of oestrogen biosynthesis|up regulation of oestrogen biosynthetic process|up regulation of estrogen biosynthesis|up regulation of estrogen biosynthetic process|up-regulation of estrogen synthesis http://purl.obolibrary.org/obo/GO_1904078 GO:1904077 biolink:BiologicalProcess negative regulation of estrogen biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process. go-plus.json downregulation of oestrogen biosynthesis|downregulation of oestrogen biosynthetic process|negative regulation of estrogen anabolism|down-regulation of estrogen anabolism|down-regulation of estrogen biosynthetic process|negative regulation of estrogen biosynthesis|down regulation of oestrogen biosynthesis|down-regulation of estrogen biosynthesis|down regulation of oestrogen biosynthetic process|inhibition of oestrogen biosynthetic process|negative regulation of estrogen synthesis|down-regulation of estrogen synthesis|inhibition of oestrogen biosynthesis|negative regulation of estrogen formation|down-regulation of estrogen formation|downregulation of estrogen anabolism|inhibition of estrogen biosynthesis|inhibition of estrogen biosynthetic process|downregulation of estrogen synthesis|down regulation of estrogen anabolism|inhibition of estrogen anabolism|downregulation of estrogen formation|down regulation of estrogen synthesis|inhibition of estrogen synthesis|down regulation of estrogen formation|down-regulation of oestrogen biosynthesis|negative regulation of oestrogen biosynthetic process|down regulation of estrogen biosynthesis|negative regulation of oestrogen biosynthesis|down-regulation of oestrogen biosynthetic process|down regulation of estrogen biosynthetic process|inhibition of estrogen formation|downregulation of estrogen biosynthetic process|downregulation of estrogen biosynthesis http://purl.obolibrary.org/obo/GO_1904077 GO:1904076 biolink:BiologicalProcess regulation of estrogen biosynthetic process Any process that modulates the frequency, rate or extent of estrogen biosynthetic process. go-plus.json regulation of oestrogen biosynthesis|regulation of oestrogen biosynthetic process|regulation of estrogen anabolism|regulation of estrogen synthesis|regulation of estrogen formation|regulation of estrogen biosynthesis http://purl.obolibrary.org/obo/GO_1904076 GO:1904075 biolink:BiologicalProcess positive regulation of trophectodermal cell proliferation Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. go-plus.json upregulation of trophectoderm cell proliferation|up regulation of trophectodermal cell proliferation|up-regulation of trophectoderm cell proliferation|activation of trophectoderm cell proliferation|upregulation of trophectodermal cell proliferation|positive regulation of trophectoderm cell proliferation|up-regulation of trophectodermal cell proliferation|activation of trophectodermal cell proliferation|up regulation of trophectoderm cell proliferation http://purl.obolibrary.org/obo/GO_1904075 GO:1904074 biolink:BiologicalProcess negative regulation of trophectodermal cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. go-plus.json down-regulation of trophectodermal cell proliferation|down regulation of trophectoderm cell proliferation|inhibition of trophectoderm cell proliferation|downregulation of trophectodermal cell proliferation|down regulation of trophectodermal cell proliferation|inhibition of trophectodermal cell proliferation|down-regulation of trophectoderm cell proliferation|negative regulation of trophectoderm cell proliferation|downregulation of trophectoderm cell proliferation http://purl.obolibrary.org/obo/GO_1904074 GO:1904073 biolink:BiologicalProcess regulation of trophectodermal cell proliferation Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. go-plus.json regulation of trophectoderm cell proliferation http://purl.obolibrary.org/obo/GO_1904073 GO:1904072 biolink:BiologicalProcess presynaptic active zone disassembly The disaggregation of a presynaptic active zone into its constituent components. go-plus.json pre-synaptic active zone component disassembly|pre-synaptic active zone disassembly http://purl.obolibrary.org/obo/GO_1904072 GO:1904071 biolink:BiologicalProcess presynaptic active zone assembly The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix. go-plus.json pre-synaptic active zone assembly|pre-synaptic active zone component formation|pre-synaptic active zone formation|presynaptic active zone formation|pre-synaptic active zone component assembly http://purl.obolibrary.org/obo/GO_1904071 GO:1904070 biolink:BiologicalProcess ascaroside biosynthetic process The chemical reactions and pathways resulting in the formation of ascaroside. go-plus.json ascaroside anabolism|ascaroside synthesis|ascaroside formation|ascaroside biosynthesis http://purl.obolibrary.org/obo/GO_1904070 NCBITaxon:815 biolink:OrganismalEntity Bacteroidaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_815 NCBITaxon:813 biolink:OrganismalEntity Chlamydia trachomatis go-plus.json Rickettsia trachomae|Chlamydozoon trachomatis|Rickettsia trachomatis http://purl.obolibrary.org/obo/NCBITaxon_813 NCBITaxon:818 biolink:OrganismalEntity Bacteroides thetaiotaomicron go-plus.json Pseudobacterium thetaiotaomicron|Bacteroides fragilis subsp. thetaiotaomicron|Sphaerocillus thetaiotaomicron|Bacillus thetaiotaomicron http://purl.obolibrary.org/obo/NCBITaxon_818 NCBITaxon:816 biolink:OrganismalEntity Bacteroides go-plus.json Ristella|Capsularis http://purl.obolibrary.org/obo/NCBITaxon_816 NCBITaxon:810 biolink:OrganismalEntity Chlamydia go-plus.json "Prowazekia" Coles 1953|Chlamydophila|Rickettsiaformis|Bedsonia|Miyagawanella|Rakeia http://purl.obolibrary.org/obo/NCBITaxon_810 GO:1904089 biolink:BiologicalProcess negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of neuron apoptotic process. go-plus.json negative regulation of neuron apoptosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of programmed cell death, neurons by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904089 GO:1904088 biolink:BiologicalProcess positive regulation of epiboly involved in gastrulation with mouth forming second Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second. go-plus.json up regulation of epiboly involved in gastrulation with mouth forming second|upregulation of epiboly involved in gastrulation with mouth forming second|up-regulation of epiboly involved in gastrulation with mouth forming second|activation of epiboly involved in gastrulation with mouth forming second http://purl.obolibrary.org/obo/GO_1904088 GO:1904087 biolink:BiologicalProcess negative regulation of epiboly involved in gastrulation with mouth forming second Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second. go-plus.json downregulation of epiboly involved in gastrulation with mouth forming second|down regulation of epiboly involved in gastrulation with mouth forming second|inhibition of epiboly involved in gastrulation with mouth forming second|down-regulation of epiboly involved in gastrulation with mouth forming second http://purl.obolibrary.org/obo/GO_1904087 GO:1904086 biolink:BiologicalProcess regulation of epiboly involved in gastrulation with mouth forming second Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second. go-plus.json http://purl.obolibrary.org/obo/GO_1904086 GO:1904085 biolink:BiologicalProcess obsolete positive regulation of epiboly OBSOLETE. Any process that activates or increases the frequency, rate or extent of epiboly. go-plus.json positive regulation of epiboly|upregulation of epiboly|up regulation of epiboly|activation of epiboly|up-regulation of epiboly http://purl.obolibrary.org/obo/GO_1904085 GO:1904084 biolink:BiologicalProcess obsolete negative regulation of epiboly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epiboly. go-plus.json negative regulation of epiboly|down regulation of epiboly|downregulation of epiboly|down-regulation of epiboly|inhibition of epiboly http://purl.obolibrary.org/obo/GO_1904084 GO:1904083 biolink:BiologicalProcess obsolete regulation of epiboly OBSOLETE. Any process that modulates the frequency, rate or extent of epiboly. go-plus.json regulation of epiboly http://purl.obolibrary.org/obo/GO_1904083 GO:1904082 biolink:BiologicalProcess pyrimidine nucleobase transmembrane transport The process in which pyrimidine is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904082 GO:1904081 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation. go-plus.json upregulation of transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron differentiation|upregulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from Pol II promoter involved in neuron differentiation|up-regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|activation of transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron differentiation|positive regulation of global transcription from Pol II promoter involved in neuron differentiation|activation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|up-regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation http://purl.obolibrary.org/obo/GO_1904081 GO:1904080 biolink:BiologicalProcess obsolete positive regulation of transcription from RNA polymerase II promoter involved in neuron fate specification OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron fate specification. go-plus.json up-regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of global transcription from Pol II promoter involved in neuron fate specification|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron fate specification|positive regulation of transcription from Pol II promoter involved in neuron fate specification|up regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|up regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|up-regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|activation of transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of transcription from RNA polymerase II promoter involved in neuron fate specification|activation of global transcription from RNA polymerase II promoter involved in neuron fate specification http://purl.obolibrary.org/obo/GO_1904080 NCBITaxon:809 biolink:OrganismalEntity Chlamydiaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_809 CHEBI:136485 biolink:ChemicalSubstance 8(S),15(S)-DiHETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_136485 GO:1904099 biolink:BiologicalProcess negative regulation of protein O-linked glycosylation Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation. go-plus.json down-regulation of protein O-linked glycosylation|down regulation of protein amino acid O-linked glycosylation|downregulation of protein O-linked glycosylation|downregulation of protein amino acid O-linked glycosylation|down regulation of protein O-linked glycosylation|inhibition of protein O-linked glycosylation|negative regulation of protein amino acid O-linked glycosylation|down-regulation of protein amino acid O-linked glycosylation|inhibition of protein amino acid O-linked glycosylation http://purl.obolibrary.org/obo/GO_1904099 GO:1904098 biolink:BiologicalProcess regulation of protein O-linked glycosylation Any process that modulates the frequency, rate or extent of protein O-linked glycosylation. go-plus.json regulation of protein amino acid O-linked glycosylation http://purl.obolibrary.org/obo/GO_1904098 GO:1904097 biolink:CellularComponent acid phosphatase complex A protein complex which is capable of acid phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904097 GO:1904096 biolink:CellularComponent protein tyrosine phosphatase complex A protein complex which is capable of protein tyrosine phosphatase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904096 GO:1904095 biolink:BiologicalProcess negative regulation of endosperm development Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development. go-plus.json down regulation of endosperm development|downregulation of endosperm development|down-regulation of endosperm development|inhibition of endosperm development http://purl.obolibrary.org/obo/GO_1904095 GO:1904094 biolink:BiologicalProcess positive regulation of autophagic cell death Any process that activates or increases the frequency, rate or extent of autophagic cell death. go-plus.json up regulation of programmed cell death by macroautophagy|activation of programmed cell death by macroautophagy|positive regulation of programmed cell death by macroautophagy|up regulation of autophagic cell death|up regulation of type II programmed cell death|activation of autophagic cell death|positive regulation of type II programmed cell death|up-regulation of programmed cell death by macroautophagy|activation of type II programmed cell death|up-regulation of type II programmed cell death|up-regulation of autophagic cell death|upregulation of programmed cell death by macroautophagy|upregulation of autophagic cell death|upregulation of type II programmed cell death http://purl.obolibrary.org/obo/GO_1904094 GO:1904093 biolink:BiologicalProcess negative regulation of autophagic cell death Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death. go-plus.json down regulation of type II programmed cell death|down regulation of autophagic cell death|downregulation of autophagic cell death|downregulation of type II programmed cell death|down-regulation of programmed cell death by macroautophagy|negative regulation of programmed cell death by macroautophagy|inhibition of programmed cell death by macroautophagy|down-regulation of autophagic cell death|down-regulation of type II programmed cell death|negative regulation of type II programmed cell death|inhibition of autophagic cell death|down regulation of programmed cell death by macroautophagy|inhibition of type II programmed cell death|downregulation of programmed cell death by macroautophagy http://purl.obolibrary.org/obo/GO_1904093 CHEBI:136494 biolink:ChemicalSubstance N-(2-ethyl-6-methylphenyl)-2-chloroacetamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136494 chebi_ph7_3 GO:1904092 biolink:BiologicalProcess regulation of autophagic cell death Any process that modulates the frequency, rate or extent of autophagic cell death. go-plus.json regulation of programmed cell death by autophagy|regulation of type II programmed cell death|regulation of programmed cell death by macroautophagy|regulation of autophagic death http://purl.obolibrary.org/obo/GO_1904092 CHEBI:136493 biolink:ChemicalSubstance phosphatidylinositol (16:0/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136493 GO:1904091 biolink:MolecularActivity peptidyl carrier protein activity Binding an amino-acid derived peptidyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the peptidyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. Peptidyl carrier protein (PCP) is involved in nonribosomal peptide biosynthetic process. go-plus.json oligopeptido binding involved in nonribosomal peptide formation|oligopeptide binding involved in non-ribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide formation|peptidyl carrier protein|peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide anabolism|oligopeptide binding involved in non-ribosomal peptide formation|peptidyl binding involved in nonribosomal peptide biosynthetic process|peptidyl binding involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide biosynthesis|Oligopeptid binding involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in nonribosomal peptide biosynthetic process|oligopeptido binding involved in nonribosomal peptide biosynthesis|oligopeptido binding involved in non-ribosomal peptide biosynthetic process|oligopeptide binding involved in nonribosomal peptide anabolism|oligopeptido binding involved in non-ribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide formation|Oligopeptid binding involved in non-ribosomal peptide biosynthesis|Oligopeptid binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide formation|Oligopeptid binding involved in nonribosomal peptide synthetase|oligopeptido binding involved in nonribosomal peptide synthetase|oligopeptide binding involved in nonribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide biosynthetic process|oligopeptide binding involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in nonribosomal peptide formation|oligopeptides binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide biosynthesis|peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide biosynthetic process|oligopeptide binding involved in nonribosomal peptide synthetase|PCP|oligopeptido binding involved in nonribosomal peptide anabolism|Oligopeptid binding involved in nonribosomal peptide anabolism|oligopeptide binding involved in non-ribosomal peptide biosynthesis|oligopeptide binding involved in non-ribosomal peptide biosynthetic process|Oligopeptid binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide synthesis|oligopeptides binding involved in nonribosomal peptide synthetase|Oligopeptid binding involved in non-ribosomal peptide formation|oligopeptido binding involved in non-ribosomal peptide formation http://purl.obolibrary.org/obo/GO_1904091 CHEBI:136492 biolink:ChemicalSubstance N-(2,6-diethylphenyl)-2-chloroacetamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136492 chebi_ph7_3 GO:1904090 biolink:CellularComponent peptidase inhibitor complex A protein complex which is capable of peptidase inhibitor activity. go-plus.json Cathepsin-B - cystatin-A complex http://purl.obolibrary.org/obo/GO_1904090 GO:0003299 biolink:BiologicalProcess muscle hypertrophy in response to stress The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis. go-plus.json http://purl.obolibrary.org/obo/GO_0003299 GO:0003296 biolink:BiologicalProcess apoptotic process involved in atrial ventricular junction remodeling Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction. go-plus.json apoptosis involved in atrial ventricular junction remodeling|apoptosis involved in atrioventricular junction remodeling|apoptosis involved in atrio-ventricular junction remodeling http://purl.obolibrary.org/obo/GO_0003296 GO:0003295 biolink:BiologicalProcess cell proliferation involved in atrial ventricular junction remodeling The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction. go-plus.json cell proliferation involved in atrioventricular junction remodeling|cell proliferation involved in atrio-ventricular junction remodeling http://purl.obolibrary.org/obo/GO_0003295 GO:0003298 biolink:BiologicalProcess physiological muscle hypertrophy The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. go-plus.json http://purl.obolibrary.org/obo/GO_0003298 GO:0003297 biolink:BiologicalProcess heart wedging The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003297 GO:0003292 biolink:BiologicalProcess cardiac septum cell differentiation The process in which an endocardial cushion cell becomes a cell of a cardiac septum. go-plus.json http://purl.obolibrary.org/obo/GO_0003292 GO:0003291 biolink:BiologicalProcess atrial septum intermedium morphogenesis The process in which anatomical structure of an atrial septum intermedium is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003291 GO:0003294 biolink:BiologicalProcess atrial ventricular junction remodeling The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle. go-plus.json atrioventricular junction remodeling|atrio-ventricular junction remodeling http://purl.obolibrary.org/obo/GO_0003294 GO:0003293 biolink:BiologicalProcess heart valve cell differentiation The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve. go-plus.json http://purl.obolibrary.org/obo/GO_0003293 NCBITaxon:848 biolink:OrganismalEntity Fusobacterium go-plus.json Fusibacterium http://purl.obolibrary.org/obo/NCBITaxon_848 CL:1000549 biolink:Cell kidney cortex collecting duct epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000549 CL:1000548 biolink:Cell kidney outer medulla collecting duct epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000548 CL:1000547 biolink:Cell kidney inner medulla collecting duct epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000547 CHEBI:136471 biolink:ChemicalSubstance phosphatidylethanolamine (16:1/16:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136471 GO:0052205 biolink:BiologicalProcess modulation of molecular function in other organism involved in symbiotic interaction The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modification of molecular function in other organism during symbiotic interaction|modification of protein function in other organism during symbiotic interaction|modulation of molecular function in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052205 CHEBI:30408 biolink:ChemicalSubstance iron-sulfur cluster go-plus.json http://purl.obolibrary.org/obo/CHEBI_30408 chebi_ph7_3 GO:0052204 biolink:BiologicalProcess negative regulation of molecular function in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json down regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism|negative regulation of protein function in other organism during symbiotic interaction|downregulation of protein function in other organism during symbiotic interaction|down-regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052204 CHEBI:30407 biolink:ChemicalSubstance 4-phospho-L-aspartate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30407 GO:0052203 biolink:BiologicalProcess obsolete modulation of catalytic activity in other organism involved in symbiotic interaction OBSOLETE. The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of enzyme activity within other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052203 GO:0052202 biolink:BiologicalProcess obsolete negative regulation by symbiont of defense-related host cell wall callose deposition OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json inhibition by symbiont of defense-related host cell wall callose deposition|down regulation by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|downregulation by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|down-regulation by symbiont of defense-related host cell wall callose deposition|negative regulation by symbiont of defense-related host callose deposition http://purl.obolibrary.org/obo/GO_0052202 GO:0052209 biolink:BiologicalProcess obsolete interaction with other organism via substance secreted by type IV secretion system involved in symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type IV secretion system, where the two organisms are in a symbiotic interaction. go-plus.json interaction with other organism via substance secreted by type IV secretion system during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052209 GO:0052208 biolink:BiologicalProcess obsolete modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type IV secretion system in the first organism, where the two organisms are in a symbiotic interaction. go-plus.json modification of morphology or physiology of other organism via substance secreted by type IV secretion system during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052208 GO:0052207 biolink:BiologicalProcess obsolete modification of morphology or physiology of other organism via protein secreted by type III secretion system involved in symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type III secretion system in the first organism, where the two organisms are in a symbiotic interaction. go-plus.json modification of morphology or physiology of other organism via protein secreted by type III secretion system during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052207 GO:0052206 biolink:BiologicalProcess obsolete modification of morphology or physiology of other organism via protein secreted by type II secretion system involved in symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type II secretion system in the first organism, where the two organisms are in a symbiotic interaction. go-plus.json modification of morphology or physiology of other organism via protein secreted by type II secretion system during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052206 GO:0042882 biolink:BiologicalProcess L-arabinose transmembrane transport The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json L-arabinose transport http://purl.obolibrary.org/obo/GO_0042882 GO:0042881 biolink:MolecularActivity D-galactonate transmembrane transporter activity Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042881 GO:0042884 biolink:BiologicalProcess microcin transport The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042884 GO:0042883 biolink:BiologicalProcess cysteine transport The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json L-cysteine transport http://purl.obolibrary.org/obo/GO_0042883 CHEBI:29412 biolink:ChemicalSubstance oxonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_29412 GO:0042880 biolink:MolecularActivity D-glucuronate transmembrane transporter activity Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042880 CHEBI:30409 biolink:ChemicalSubstance iron-sulfur-molybdenum cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_30409 chebi_ph7_3 GO:0042889 biolink:BiologicalProcess 3-phenylpropionic acid transport The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json HCA transport|hydrocinnamic acid transport|3-phenylpropionate transport http://purl.obolibrary.org/obo/GO_0042889 GO:0042886 biolink:BiologicalProcess amide transport The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042886 goslim_pir CHEBI:78385 biolink:ChemicalSubstance 1-palmityl-2-acetyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78385 chebi_ph7_3 GO:0042885 biolink:BiologicalProcess microcin B17 transport The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042885 GO:0042888 biolink:MolecularActivity molybdenum ion transmembrane transporter activity Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042888 GO:0042887 biolink:MolecularActivity amide transmembrane transporter activity Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other. go-plus.json amine/amide/polyamine channel activity http://purl.obolibrary.org/obo/GO_0042887 CHEBI:78387 biolink:ChemicalSubstance 1-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78387 chebi_ph7_3 GO:0052201 biolink:BiologicalProcess response to symbiont defenses Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052201 GO:0052200 biolink:BiologicalProcess response to host defenses Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response to host defense molecules|response of symbiont to host defense molecules|maintenance of symbiont tolerance to host defense molecules http://purl.obolibrary.org/obo/GO_0052200 GO:0052216 biolink:BiologicalProcess obsolete chemotaxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json chemotaxis in environment of other organism during symbiotic interaction|chemotaxis in response to environment of other organism http://purl.obolibrary.org/obo/GO_0052216 GO:0052215 biolink:BiologicalProcess obsolete energy taxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in the environment of a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json energy taxis in response to environment of other organism|energy taxis in environment of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052215 GO:0052214 biolink:BiologicalProcess obsolete metabolism of substance in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism of substance in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052214 GO:0052213 biolink:BiologicalProcess obsolete interaction with symbiont via secreted substance OBSOLETE. An interaction with a symbiont organism mediated by a substance secreted by a host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json interaction with symbiont via secreted substance involved in symbiotic interaction|interaction with symbiont via secreted substance during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052213 GO:0052219 biolink:BiologicalProcess obsolete negative energy taxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json negative energy taxis in environment of other organism during symbiotic interaction|negative energy taxis in response to environment of other organism http://purl.obolibrary.org/obo/GO_0052219 GO:0052218 biolink:BiologicalProcess obsolete positive energy taxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json positive energy taxis in environment of other organism during symbiotic interaction|positive energy taxis in response to environment of other organism http://purl.obolibrary.org/obo/GO_0052218 CHEBI:30413 biolink:ChemicalSubstance heme go-plus.json http://purl.obolibrary.org/obo/CHEBI_30413 chebi_ph7_3 GO:0052217 biolink:BiologicalProcess obsolete aerotaxis in environment of other organism involved in symbiotic interaction OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json aerotaxis in environment of other organism during symbiotic interaction|aerotaxis in response to environment of other organism http://purl.obolibrary.org/obo/GO_0052217 CHEBI:30412 biolink:ChemicalSubstance monoatomic dication go-plus.json http://purl.obolibrary.org/obo/CHEBI_30412 chebi_ph7_3 GO:0042893 biolink:BiologicalProcess polymyxin transport The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042893 GO:0042892 biolink:BiologicalProcess chloramphenicol transmembrane transport The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other. go-plus.json chloramphenicol transport http://purl.obolibrary.org/obo/GO_0042892 GO:0042895 biolink:MolecularActivity obsolete antibiotic transmembrane transporter activity OBSOLETE. Enables the transfer of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, from one side of a membrane to the other. go-plus.json antibiotic transporter activity http://purl.obolibrary.org/obo/GO_0042895 GO:0042894 biolink:BiologicalProcess fosmidomycin transport The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042894 GO:0042891 biolink:BiologicalProcess obsolete antibiotic transport OBSOLETE. The directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042891 GO:0042890 biolink:MolecularActivity 3-phenylpropionic acid transmembrane transporter activity Enables the transfer of 3-phenylpropionic acid from one side of a membrane to the other. go-plus.json hydrocinnamic acid transporter activity|3-phenylpropionate acid transporter activity|HCA transporter activity http://purl.obolibrary.org/obo/GO_0042890 UBERON:0007245 biolink:AnatomicalEntity nuclear complex of neuraxis Gray matter of the central nervous system which is a collection of clustered nuclei. go-plus.json nuclear complex|neural nuclei|cluster of neural nuclei http://purl.obolibrary.org/obo/UBERON_0007245 UBERON:0007244 biolink:AnatomicalEntity inferior olivary nucleus The inferior olivary nucleus is the largest nucleus situated in the olivary body, part of the medulla oblongata. go-plus.json inferior olive http://purl.obolibrary.org/obo/UBERON_0007244 CHEBI:78390 biolink:ChemicalSubstance 1-hexadecyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78390 chebi_ph7_3 UBERON:0007243 biolink:AnatomicalEntity tunica media of vein A tunica media that is part of a vein. go-plus.json venous media|tunica media (venae) http://purl.obolibrary.org/obo/UBERON_0007243 GO:0042897 biolink:MolecularActivity polymyxin transmembrane transporter activity Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other. go-plus.json polymyxin transporter activity http://purl.obolibrary.org/obo/GO_0042897 UBERON:0007242 biolink:AnatomicalEntity tunica intima of vein A tunica intima that is part of a vein. go-plus.json tunica interna (intima)(venae)|venous intima http://purl.obolibrary.org/obo/UBERON_0007242 CHEBI:78396 biolink:ChemicalSubstance 4-hydroxy-3-polyprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78396 chebi_ph7_3 UBERON:0007241 biolink:AnatomicalEntity tunica adventitia of vein A tunica adventitia that is part of a vein. go-plus.json tunica externa (adventitia)(venae)|venous adventitia http://purl.obolibrary.org/obo/UBERON_0007241 GO:0042896 biolink:MolecularActivity chloramphenicol transmembrane transporter activity Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other. go-plus.json chloramphenicol transporter activity http://purl.obolibrary.org/obo/GO_0042896 GO:0042899 biolink:BiologicalProcess arabinan transmembrane transport The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json arabinan transport http://purl.obolibrary.org/obo/GO_0042899 UBERON:0007240 biolink:AnatomicalEntity tunica adventitia of artery A tunica adventitia that is part of a artery. go-plus.json arterial adventitia|tunica externa (adventitia)(arteriae) http://purl.obolibrary.org/obo/UBERON_0007240 GO:0042898 biolink:MolecularActivity fosmidomycin transmembrane transporter activity Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other. go-plus.json fosmidomycin transporter activity http://purl.obolibrary.org/obo/GO_0042898 CHEBI:30411 biolink:ChemicalSubstance cobalamin go-plus.json http://purl.obolibrary.org/obo/CHEBI_30411 GO:0052212 biolink:BiologicalProcess obsolete modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction. go-plus.json modification of morphology or physiology of other organism via secreted substance during symbiotic interaction|modification of host morphology or physiology via effector molecule|modification of host morphology or physiology via ellicitor http://purl.obolibrary.org/obo/GO_0052212 GO:0052211 biolink:BiologicalProcess obsolete interaction with other organism via protein secreted by type II secretion system involved in symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type II secretion system, where the two organisms are in a symbiotic interaction. go-plus.json interaction with other organism via protein secreted by type II secretion system during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052211 GO:0052210 biolink:BiologicalProcess obsolete interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type III secretion system, where the two organisms are in a symbiotic interaction. go-plus.json interaction with other organism via protein secreted by type III secretion system during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052210 UBERON:0007247 biolink:AnatomicalEntity nucleus of superior olivary complex Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei. go-plus.json superior olivary complex nucleus http://purl.obolibrary.org/obo/UBERON_0007247 GO:0052227 biolink:BiologicalProcess obsolete catabolism of substance in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the breakdown of substances, where the two organisms are in a symbiotic interaction. go-plus.json catabolism of substance in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052227 GO:0052226 biolink:BiologicalProcess obsolete biosynthesis of substance in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the formation of substances, where the two organisms are in a symbiotic interaction. go-plus.json biosynthesis of substance in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052226 GO:0052225 biolink:BiologicalProcess obsolete energy taxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on or near a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json energy taxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052225 GO:0052224 biolink:BiologicalProcess obsolete energy taxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism within a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json energy taxis within other organism during symbiotic interaction|energy taxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052224 GO:0052229 biolink:BiologicalProcess obsolete metabolism of macromolecule in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism of macromolecule in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052229 GO:0052228 biolink:BiologicalProcess obsolete metabolism by symbiont of host protein OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052228 CL:1000510 biolink:Cell kidney glomerular epithelial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000510 GO:0052223 biolink:BiologicalProcess obsolete negative chemotaxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json negative chemotaxis in response to environment of other organism|negative chemotaxis in environment of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052223 UBERON:0007239 biolink:AnatomicalEntity tunica media of artery A tunica media that is part of a artery. go-plus.json arterial media|tunica media (arteriae) http://purl.obolibrary.org/obo/UBERON_0007239 GO:0052222 biolink:BiologicalProcess obsolete negative aerotaxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json negative aerotaxis in response to environment of other organism|negative aerotaxis in environment of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052222 UBERON:0007238 biolink:AnatomicalEntity 1st arch maxillary component go-plus.json http://purl.obolibrary.org/obo/UBERON_0007238 GO:0052221 biolink:BiologicalProcess obsolete positive chemotaxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json positive chemotaxis in environment of other organism during symbiotic interaction|positive chemotaxis in response to environment of other organism http://purl.obolibrary.org/obo/GO_0052221 UBERON:0007237 biolink:AnatomicalEntity 1st arch mandibular component go-plus.json ventral visceral arch 1|ventral mandibular arch|ventral pharyngeal arch 1 http://purl.obolibrary.org/obo/UBERON_0007237 GO:0052220 biolink:BiologicalProcess obsolete positive aerotaxis in environment of other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json positive aerotaxis in response to environment of other organism|positive aerotaxis in environment of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052220 GO:0052238 biolink:BiologicalProcess obsolete aerotaxis on or near other organism involved in symbiotic interaction OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json aerotaxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052238 GO:0052237 biolink:BiologicalProcess obsolete aerotaxis in other organism involved in symbiotic interaction OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json aerotaxis in other organism during symbiotic interaction|aerotaxis within other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052237 GO:0052236 biolink:BiologicalProcess obsolete negative chemotaxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json negative chemotaxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052236 GO:0052235 biolink:BiologicalProcess obsolete negative aerotaxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json negative aerotaxis within other organism during symbiotic interaction|negative aerotaxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052235 GO:0052239 biolink:BiologicalProcess obsolete negative chemotaxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json negative chemotaxis within other organism during symbiotic interaction|negative chemotaxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052239 CL:1000507 biolink:Cell kidney tubule cell go-plus.json http://purl.obolibrary.org/obo/CL_1000507 CL:1000504 biolink:Cell kidney medulla cell go-plus.json http://purl.obolibrary.org/obo/CL_1000504 CL:1000500 biolink:Cell kidney interstitial cell go-plus.json http://purl.obolibrary.org/obo/CL_1000500 UBERON:0007223 biolink:AnatomicalEntity osseus cochlea The osseous cochlea is the bony foundation that forms the small shell arrangement for the cochlear nerve. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007223 UBERON:0007220 biolink:AnatomicalEntity late embryonic stage An embryo stage that covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. go-plus.json embryo late growth stage|fetal stage|embryo late (growth) stage|fetus|fetus stage|embryo late stage http://purl.obolibrary.org/obo/UBERON_0007220 GO:0052230 biolink:BiologicalProcess modulation of intracellular transport in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of intracellular transport in other organism during symbiotic interaction|modulation of intracellular trafficking in other organism http://purl.obolibrary.org/obo/GO_0052230 GO:0052234 biolink:BiologicalProcess obsolete negative aerotaxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json negative aerotaxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052234 UBERON:0007228 biolink:AnatomicalEntity vestibular nucleus A cranial nucleus for the vestibular nerve. [WP,unvetted]. go-plus.json vestibular nucleus of eighth cranial nerve|vestibular nucleus of acoustic nerve|vestibular VIII nucleus http://purl.obolibrary.org/obo/UBERON_0007228 GO:0052233 biolink:BiologicalProcess obsolete positive aerotaxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json positive aerotaxis within other organism during symbiotic interaction|positive aerotaxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052233 GO:0052232 biolink:BiologicalProcess obsolete positive aerotaxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json positive aerotaxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052232 GO:0052231 biolink:BiologicalProcess obsolete modulation of phagocytosis in other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of phagocytosis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052231 GO:0052249 biolink:BiologicalProcess modulation of RNA levels in other organism involved in symbiotic interaction The alteration by an organism of the levels of RNA in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of RNA levels in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052249 GO:0052248 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052248 GO:0052247 biolink:BiologicalProcess obsolete positive energy taxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json positive energy taxis within other organism during symbiotic interaction|positive energy taxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052247 GO:0052246 biolink:BiologicalProcess obsolete positive energy taxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json positive energy taxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052246 UBERON:0007293 biolink:AnatomicalEntity presumptive rhombomere 6 A presumptive structure that has the potential to develop into a rhombomere 6. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007293 UBERON:0007292 biolink:AnatomicalEntity presumptive rhombomere 5 A presumptive structure that has the potential to develop into a rhombomere 5. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007292 UBERON:0007291 biolink:AnatomicalEntity presumptive rhombomere 4 A presumptive structure that has the potential to develop into a rhombomere 4. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007291 UBERON:0007290 biolink:AnatomicalEntity presumptive rhombomere 3 A presumptive structure that has the potential to develop into a rhombomere 3. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007290 GO:1904002 biolink:BiologicalProcess regulation of sebum secreting cell proliferation Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation. go-plus.json regulation of sebocyte proliferation http://purl.obolibrary.org/obo/GO_1904002 GO:1904001 biolink:BiologicalProcess obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage. go-plus.json positive regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904001 GO:1904000 biolink:BiologicalProcess positive regulation of eating behavior Any process that activates or increases the frequency, rate or extent of eating behavior. go-plus.json up regulation of eating behaviour|upregulation of eating behavior|upregulation of eating behaviour|up regulation of eating behavior|activation of eating behavior|up-regulation of eating behaviour|activation of eating behaviour|up-regulation of eating behavior|positive regulation of eating behaviour http://purl.obolibrary.org/obo/GO_1904000 UBERON:0007298 biolink:AnatomicalEntity pronephric proximal convoluted tubule A proximal convoluted tubule that is part of a pronephros. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007298 UBERON:0007297 biolink:AnatomicalEntity presumptive pronephric mesoderm A presumptive structure that has the potential to develop into a pronephric mesoderm. go-plus.json nephron primordium http://purl.obolibrary.org/obo/UBERON_0007297 UBERON:0007296 biolink:AnatomicalEntity presumptive rhombomere 2 A presumptive structure that has the potential to develop into a rhombomere 2. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007296 UBERON:0007295 biolink:AnatomicalEntity presumptive rhombomere 8 A presumptive structure that has the potential to develop into a rhombomere 8. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007295 UBERON:0007294 biolink:AnatomicalEntity presumptive rhombomere 7 A presumptive structure that has the potential to develop into a rhombomere 7. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007294 GO:0052241 biolink:BiologicalProcess obsolete positive chemotaxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json positive chemotaxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052241 GO:0052240 biolink:BiologicalProcess obsolete positive chemotaxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json positive chemotaxis within other organism during symbiotic interaction|positive chemotaxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052240 GO:0052245 biolink:BiologicalProcess obsolete negative energy taxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json negative energy taxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052245 GO:0052244 biolink:BiologicalProcess obsolete negative energy taxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. go-plus.json negative energy taxis within other organism during symbiotic interaction|negative energy taxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052244 GO:0052243 biolink:BiologicalProcess obsolete chemotaxis on or near other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near a second organism, where the two organisms are in a symbiotic interaction. go-plus.json chemotaxis on or near other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052243 GO:0052242 biolink:BiologicalProcess obsolete chemotaxis in other organism involved in symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json chemotaxis within other organism during symbiotic interaction|chemotaxis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052242 GO:0052259 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052259 GO:0052258 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052258 GO:0052257 biolink:BiologicalProcess obsolete pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json general elicitor-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism during symbiotic interaction|PAMP-dependent induction of innate immunity of other organism|general elicitor dependent induction of innate immunity of other organism|MAMP-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism involved in symbiotic interaction|PAMP dependent induction of innate immunity of other organism|MAMP dependent induction of innate immunity of other organism http://purl.obolibrary.org/obo/GO_0052257 UBERON:0007282 biolink:AnatomicalEntity presumptive segmental plate A presumptive structure that has the potential to develop into a presomitic mesoderm. go-plus.json presumptive segmental plates http://purl.obolibrary.org/obo/UBERON_0007282 GO:1904009 biolink:BiologicalProcess cellular response to monosodium glutamate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904009 UBERON:0007281 biolink:AnatomicalEntity presumptive midbrain hindbrain boundary Embryonic structure that gives rise to the midbrain hindbrain boundary. go-plus.json presumptive midbrain-hindbrain boundary|presumptive MHB http://purl.obolibrary.org/obo/UBERON_0007281 UBERON:0007280 biolink:AnatomicalEntity presumptive endocardium A presumptive structure that has the potential to develop into a endocardium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007280 GO:1904008 biolink:BiologicalProcess response to monosodium glutamate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904008 GO:1904007 biolink:BiologicalProcess positive regulation of phospholipase D activity Any process that activates or increases the frequency, rate or extent of phospholipase D activity. go-plus.json upregulation of phosphatidylcholine phosphatidohydrolase activity|positive regulation of choline phosphatase activity|upregulation of phospholipase D activity|upregulation of lecithinase D activity|up regulation of choline phosphatase activity|up regulation of lipophosphodiesterase II activity|positive regulation of lipophosphodiesterase II activity|activation of lipophosphodiesterase II activity|up regulation of phosphatidylcholine phosphatidohydrolase activity|up-regulation of phospholipase D activity|up-regulation of lecithinase D activity|activation of phospholipase D activity|activation of phosphatidylcholine phosphatidohydrolase activity|activation of lecithinase D activity|positive regulation of phosphatidylcholine phosphatidohydrolase activity|upregulation of choline phosphatase activity|up-regulation of lipophosphodiesterase II activity|positive regulation of lecithinase D activity|up-regulation of choline phosphatase activity|up-regulation of phosphatidylcholine phosphatidohydrolase activity|activation of choline phosphatase activity|up regulation of phospholipase D activity|up regulation of lecithinase D activity|upregulation of lipophosphodiesterase II activity http://purl.obolibrary.org/obo/GO_1904007 GO:1904006 biolink:BiologicalProcess negative regulation of phospholipase D activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity. go-plus.json down regulation of lipophosphodiesterase II activity|down regulation of phospholipase D activity|down regulation of lecithinase D activity|inhibition of lecithinase D activity|inhibition of phospholipase D activity|downregulation of lipophosphodiesterase II activity|down regulation of phosphatidylcholine phosphatidohydrolase activity|downregulation of choline phosphatase activity|downregulation of phosphatidylcholine phosphatidohydrolase activity|down regulation of choline phosphatase activity|down-regulation of lipophosphodiesterase II activity|negative regulation of lipophosphodiesterase II activity|inhibition of choline phosphatase activity|down-regulation of phosphatidylcholine phosphatidohydrolase activity|negative regulation of phosphatidylcholine phosphatidohydrolase activity|inhibition of lipophosphodiesterase II activity|down-regulation of phospholipase D activity|down-regulation of lecithinase D activity|negative regulation of lecithinase D activity|inhibition of phosphatidylcholine phosphatidohydrolase activity|downregulation of lecithinase D activity|downregulation of phospholipase D activity|negative regulation of choline phosphatase activity|down-regulation of choline phosphatase activity http://purl.obolibrary.org/obo/GO_1904006 GO:1904005 biolink:BiologicalProcess regulation of phospholipase D activity Any process that modulates the frequency, rate or extent of phospholipase D activity. go-plus.json regulation of lipophosphodiesterase II activity|regulation of phosphatidylcholine phosphatidohydrolase activity|regulation of choline phosphatase activity|regulation of lecithinase D activity http://purl.obolibrary.org/obo/GO_1904005 GO:1904004 biolink:BiologicalProcess positive regulation of sebum secreting cell proliferation Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation. go-plus.json upregulation of sebocyte proliferation|up-regulation of sebum secreting cell proliferation|activation of sebum secreting cell proliferation|up-regulation of sebocyte proliferation|up regulation of sebum secreting cell proliferation|activation of sebocyte proliferation|positive regulation of sebocyte proliferation|up regulation of sebocyte proliferation|upregulation of sebum secreting cell proliferation http://purl.obolibrary.org/obo/GO_1904004 GO:1904003 biolink:BiologicalProcess negative regulation of sebum secreting cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation. go-plus.json down regulation of sebocyte proliferation|inhibition of sebocyte proliferation|down-regulation of sebum secreting cell proliferation|down-regulation of sebocyte proliferation|negative regulation of sebocyte proliferation|downregulation of sebum secreting cell proliferation|down regulation of sebum secreting cell proliferation|inhibition of sebum secreting cell proliferation|downregulation of sebocyte proliferation http://purl.obolibrary.org/obo/GO_1904003 GO:1904013 biolink:MolecularActivity obsolete xenon atom binding OBSOLETE. Binding to xenon atom. go-plus.json http://purl.obolibrary.org/obo/GO_1904013 GO:1904012 biolink:MolecularActivity obsolete platinum binding OBSOLETE. Binding to platinum. go-plus.json http://purl.obolibrary.org/obo/GO_1904012 UBERON:0007289 biolink:AnatomicalEntity presumptive rhombomere 1 A presumptive structure that has the potential to develop into a rhombomere 1. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007289 GO:1904011 biolink:BiologicalProcess cellular response to Aroclor 1254 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904011 UBERON:0007288 biolink:AnatomicalEntity presumptive forebrain midbrain boundary A presumptive structure that has the potential to develop into a forebrain-midbrain boundary. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007288 GO:1904010 biolink:BiologicalProcess response to Aroclor 1254 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904010 UBERON:0007287 biolink:AnatomicalEntity presumptive bulbus arteriosus A presumptive structure that has the potential to develop into a bulbus arteriosus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007287 UBERON:0007286 biolink:AnatomicalEntity presumptive floor plate A presumptive structure that has the potential to develop into a floor plate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007286 UBERON:0007285 biolink:AnatomicalEntity presumptive paraxial mesoderm The part of the blastula that has the potential to develop into a paraxial mesoderm. go-plus.json future paraxial mesoderm|future paraxial mesenchyme http://purl.obolibrary.org/obo/UBERON_0007285 UBERON:0007284 biolink:AnatomicalEntity presumptive neural plate A presumptive structure that has the potential to develop into a neural plate. go-plus.json prospective neuroectoderm|prospective vegetal ectoderm http://purl.obolibrary.org/obo/UBERON_0007284 UBERON:0007283 biolink:AnatomicalEntity presumptive shield A presumptive structure that has the potential to develop into a primitive knot. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007283 GO:0052252 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052252 GO:0052251 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052251 GO:0052250 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052250 GO:0052256 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052256 GO:0052255 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052255 GO:0052254 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052254 GO:0052253 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052253 GO:0052269 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052269 GO:0052268 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052268 UBERON:0007271 biolink:AnatomicalEntity appendage musculature Any collection of muscles that is part of an appendage. go-plus.json fin musculature http://purl.obolibrary.org/obo/UBERON_0007271 UBERON:0007270 biolink:AnatomicalEntity pelvic appendage musculature Any collection of muscles that is part of a pelvic appendage. go-plus.json pelvic fin musculature http://purl.obolibrary.org/obo/UBERON_0007270 GO:1904019 biolink:BiologicalProcess epithelial cell apoptotic process Any apoptotic process in an epithelial cell. go-plus.json epithelial cell apoptosis|epitheliocyte apoptosis|epitheliocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 GO:1904018 biolink:BiologicalProcess positive regulation of vasculature development Any process that activates or increases the frequency, rate or extent of vasculature development. go-plus.json upregulation of vasculature development|up regulation of vascular system development|positive regulation of vascular system development|up regulation of vasculature development|activation of vasculature development|activation of vascular system development|up-regulation of vascular system development|up-regulation of vasculature development|upregulation of vascular system development http://purl.obolibrary.org/obo/GO_1904018 GO:1904017 biolink:BiologicalProcess cellular response to Thyroglobulin triiodothyronine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904017 GO:1904016 biolink:BiologicalProcess response to Thyroglobulin triiodothyronine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904016 GO:1904015 biolink:BiologicalProcess cellular response to serotonin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904015 GO:1904014 biolink:BiologicalProcess response to serotonin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904014 GO:1904024 biolink:BiologicalProcess negative regulation of glucose catabolic process to lactate via pyruvate Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate. go-plus.json negative regulation of homolactic fermentation|down-regulation of homolactic fermentation|negative regulation of homofermentative lactate fermentation|down-regulation of homofermentative lactate fermentation|inhibition of homofermentation|downregulation of homofermentative pathway|down regulation of glucose fermentation to lactate via pyruvate|inhibition of glucose catabolic process to lactate via pyruvate|down regulation of homofermentative pathway|inhibition of glucose fermentation to lactate via pyruvate|downregulation of homolactate fermentation|inhibition of homofermentative lactate fermentation|inhibition of homolactic fermentation|inhibition of homofermentative pathway|down regulation of homolactate fermentation|inhibition of homolactate fermentation|down regulation of glucose catabolic process to lactate via pyruvate|negative regulation of homofermentation|down-regulation of homofermentation|down regulation of homolactic fermentation|down regulation of homofermentative lactate fermentation|downregulation of glucose catabolic process to lactate via pyruvate|down-regulation of glucose fermentation to lactate via pyruvate|negative regulation of glucose fermentation to lactate via pyruvate|downregulation of homolactic fermentation|downregulation of homofermentative lactate fermentation|down-regulation of homofermentative pathway|negative regulation of homofermentative pathway|downregulation of homofermentation|down-regulation of glucose catabolic process to lactate via pyruvate|down-regulation of homolactate fermentation|negative regulation of homolactate fermentation|down regulation of homofermentation|downregulation of glucose fermentation to lactate via pyruvate http://purl.obolibrary.org/obo/GO_1904024 UBERON:0007279 biolink:AnatomicalEntity presumptive atrioventricular canal A presumptive structure that has the potential to develop into a atrioventricular canal. go-plus.json future atrioventricular canal|future AV canal http://purl.obolibrary.org/obo/UBERON_0007279 GO:1904023 biolink:BiologicalProcess regulation of glucose catabolic process to lactate via pyruvate Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate. go-plus.json regulation of glucose fermentation to lactate via pyruvate|regulation of homofermentative pathway|regulation of homolactate fermentation|regulation of homolactic fermentation|regulation of homofermentative lactate fermentation|regulation of homofermentation http://purl.obolibrary.org/obo/GO_1904023 UBERON:0007278 biolink:AnatomicalEntity presumptive sinus venosus Portion of tissue that is part of the heart tube and will become the sinus venosus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007278 UBERON:0007277 biolink:AnatomicalEntity presumptive hindbrain The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. go-plus.json rhombencephalon|embryonic rhombencephalon|presumptive rhombencephalon|future hindbrain http://purl.obolibrary.org/obo/UBERON_0007277 GO:1904022 biolink:BiologicalProcess positive regulation of G protein-coupled receptor internalization Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization. go-plus.json up regulation of G-protein coupled receptor internalization|upregulation of G-protein coupled receptor internalization|positive regulation of G-protein coupled receptor internalization|up-regulation of G-protein coupled receptor internalization|activation of G-protein coupled receptor internalization http://purl.obolibrary.org/obo/GO_1904022 GO:1904021 biolink:BiologicalProcess negative regulation of G protein-coupled receptor internalization Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization. go-plus.json downregulation of G-protein coupled receptor internalization|down regulation of G-protein coupled receptor internalization|inhibition of G-protein coupled receptor internalization|negative regulation of G-protein coupled receptor internalization|down-regulation of G-protein coupled receptor internalization http://purl.obolibrary.org/obo/GO_1904021 GO:1904020 biolink:BiologicalProcess regulation of G protein-coupled receptor internalization Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization. go-plus.json regulation of G-protein-coupled receptor internalization http://purl.obolibrary.org/obo/GO_1904020 UBERON:0007273 biolink:AnatomicalEntity pelvic appendage skeleton The collection of all skeletal elements in a pelvic appendage region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007273 UBERON:0007272 biolink:AnatomicalEntity pectoral appendage skeleton Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle. go-plus.json cheiropterygium http://purl.obolibrary.org/obo/UBERON_0007272 GO:0052263 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052263 GO:0052262 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052262 GO:0052261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052261 GO:0052260 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052260 GO:0052267 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052267 GO:0052266 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052266 GO:0052265 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052265 GO:0052264 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052264 GO:0052279 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052279 GO:1904029 biolink:BiologicalProcess regulation of cyclin-dependent protein kinase activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904029 GO:1904028 biolink:BiologicalProcess positive regulation of collagen fibril organization Any process that activates or increases the frequency, rate or extent of collagen fibril organization. go-plus.json up-regulation of collagen fibril organization|activation of collagen fibril organization|up-regulation of fibrillar collagen organization|positive regulation of collagen fibril organisation|up regulation of collagen fibril organisation|upregulation of fibrillar collagen organization|up regulation of collagen fibril organization|upregulation of collagen fibril organisation|up regulation of fibrillar collagen organization|upregulation of collagen fibril organization|positive regulation of fibrillar collagen organization|activation of fibrillar collagen organization|up-regulation of collagen fibril organisation|activation of collagen fibril organisation http://purl.obolibrary.org/obo/GO_1904028 GO:1904027 biolink:BiologicalProcess negative regulation of collagen fibril organization Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. go-plus.json negative regulation of collagen fibril organisation|down-regulation of collagen fibril organisation|inhibition of fibrillar collagen organization|down-regulation of collagen fibril organization|downregulation of collagen fibril organisation|down regulation of collagen fibril organisation|inhibition of collagen fibril organisation|down regulation of fibrillar collagen organization|downregulation of collagen fibril organization|downregulation of fibrillar collagen organization|down regulation of collagen fibril organization|inhibition of collagen fibril organization|negative regulation of fibrillar collagen organization|down-regulation of fibrillar collagen organization http://purl.obolibrary.org/obo/GO_1904027 GO:1904026 biolink:BiologicalProcess regulation of collagen fibril organization Any process that modulates the frequency, rate or extent of collagen fibril organization. go-plus.json regulation of collagen fibril organisation|regulation of fibrillar collagen organization|regulation of collagen fibrillogenesis http://purl.obolibrary.org/obo/GO_1904026 GO:1904025 biolink:BiologicalProcess positive regulation of glucose catabolic process to lactate via pyruvate Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate. go-plus.json positive regulation of homolactate fermentation|upregulation of homofermentation|up regulation of homolactate fermentation|up-regulation of glucose catabolic process to lactate via pyruvate|upregulation of glucose fermentation to lactate via pyruvate|up-regulation of homofermentative lactate fermentation|up-regulation of homolactic fermentation|upregulation of homofermentative pathway|activation of homofermentation|up-regulation of homofermentation|upregulation of glucose catabolic process to lactate via pyruvate|upregulation of homolactate fermentation|up-regulation of glucose fermentation to lactate via pyruvate|activation of glucose fermentation to lactate via pyruvate|upregulation of homofermentative lactate fermentation|upregulation of homolactic fermentation|activation of homofermentative pathway|up-regulation of homofermentative pathway|positive regulation of homofermentation|up-regulation of homolactate fermentation|activation of homolactate fermentation|up regulation of glucose catabolic process to lactate via pyruvate|up regulation of homofermentation|activation of glucose catabolic process to lactate via pyruvate|up regulation of homolactic fermentation|up regulation of homofermentative lactate fermentation|positive regulation of glucose fermentation to lactate via pyruvate|activation of homolactic fermentation|activation of homofermentative lactate fermentation|positive regulation of homofermentative pathway|up regulation of glucose fermentation to lactate via pyruvate|positive regulation of homolactic fermentation|positive regulation of homofermentative lactate fermentation|up regulation of homofermentative pathway http://purl.obolibrary.org/obo/GO_1904025 GO:1904035 biolink:BiologicalProcess regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process. go-plus.json regulation of epithelial cell apoptosis|regulation of epitheliocyte apoptosis|regulation of epitheliocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 GO:1904034 biolink:BiologicalProcess positive regulation of t-SNARE clustering Any process that activates or increases the frequency, rate or extent of t-SNARE clustering. go-plus.json up regulation of t-SNARE clustering|upregulation of t-SNARE clustering|up-regulation of t-SNARE clustering|activation of t-SNARE clustering http://purl.obolibrary.org/obo/GO_1904034 UBERON:0007267 biolink:AnatomicalEntity trachea pre-cartilage rings A pre-cartilage condensation that is part of a trachea. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007267 GO:1904033 biolink:BiologicalProcess negative regulation of t-SNARE clustering Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering. go-plus.json down-regulation of t-SNARE clustering|downregulation of t-SNARE clustering|down regulation of t-SNARE clustering|inhibition of t-SNARE clustering http://purl.obolibrary.org/obo/GO_1904033 GO:1904032 biolink:BiologicalProcess regulation of t-SNARE clustering Any process that modulates the frequency, rate or extent of t-SNARE clustering. go-plus.json http://purl.obolibrary.org/obo/GO_1904032 GO:1904031 biolink:BiologicalProcess positive regulation of cyclin-dependent protein kinase activity Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity. go-plus.json up-regulation of cyclin-dependent protein kinase activity|activation of cyclin-dependent protein kinase activity|up regulation of cyclin-dependent protein kinase activity|upregulation of cyclin-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_1904031 GO:0052270 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052270 GO:1904030 biolink:BiologicalProcess negative regulation of cyclin-dependent protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity. go-plus.json down-regulation of cyclin-dependent protein kinase activity|downregulation of cyclin-dependent protein kinase activity|down regulation of cyclin-dependent protein kinase activity|inhibition of cyclin-dependent protein kinase activity http://purl.obolibrary.org/obo/GO_1904030 GO:0052274 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052274 GO:0052273 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052273 GO:0052272 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052272 GO:0052271 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052271 GO:0052278 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052278 GO:0052277 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052277 GO:0052276 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052276 UBERON:0007269 biolink:AnatomicalEntity pectoral appendage musculature Any collection of muscles that is part of a pectoral appendage. go-plus.json pectoral fin musculature|pectoral fin muscle http://purl.obolibrary.org/obo/UBERON_0007269 GO:0052275 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052275 GO:0042802 biolink:MolecularActivity identical protein binding Binding to an identical protein or proteins. go-plus.json isoform-specific homophilic binding|protein homopolymerization http://purl.obolibrary.org/obo/GO_0042802 goslim_chembl GO:0042801 biolink:MolecularActivity obsolete polo kinase kinase activity OBSOLETE. Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0042801 GO:0042804 biolink:MolecularActivity obsolete protein homooligomerization activity OBSOLETE. Interacting selectively with identical proteins to form a homooligomer. go-plus.json protein homooligomerization activity|oligomerization activity http://purl.obolibrary.org/obo/GO_0042804 GO:0042803 biolink:MolecularActivity protein homodimerization activity Binding to an identical protein to form a homodimer. go-plus.json dimerization activity http://purl.obolibrary.org/obo/GO_0042803 goslim_chembl GO:0042800 biolink:MolecularActivity histone methyltransferase activity (H3-K4 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein. Reactome:R-HSA-8937016|Reactome:R-HSA-3364026|Reactome:R-HSA-8865498|Reactome:R-HSA-8936481|Reactome:R-HSA-1214188|Reactome:R-HSA-8936621|Reactome:R-HSA-8937050 go-plus.json histone H3 lysine 4-specific methyltransferase activity|histone lysine N-methyltransferase activity (H3-K4 specific)|histone methylase activity (H3-K4 specific) http://purl.obolibrary.org/obo/GO_0042800 CHEBI:30367 biolink:ChemicalSubstance pyrazol-1-ide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30367 CHEBI:78301 biolink:ChemicalSubstance dTDP-beta-L-rhodosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78301 chebi_ph7_3 GO:0042809 biolink:MolecularActivity vitamin D receptor binding Binding to a vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes. go-plus.json calciferol receptor binding|VDR binding http://purl.obolibrary.org/obo/GO_0042809 CHEBI:30366 biolink:ChemicalSubstance imidazolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_30366 GO:0042806 biolink:MolecularActivity fucose binding Binding to fucose, the pentose 6-deoxygalactose. go-plus.json http://purl.obolibrary.org/obo/GO_0042806 CHEBI:30363 biolink:ChemicalSubstance isobutane go-plus.json http://purl.obolibrary.org/obo/CHEBI_30363 chebi_ph7_3 GO:0042805 biolink:MolecularActivity actinin binding Binding to actinin, any member of a family of proteins that crosslink F-actin. go-plus.json capZ binding|beta-actinin binding http://purl.obolibrary.org/obo/GO_0042805 CHEBI:30362 biolink:ChemicalSubstance isopentane go-plus.json http://purl.obolibrary.org/obo/CHEBI_30362 chebi_ph7_3 GO:0042808 biolink:MolecularActivity obsolete neuronal Cdc2-like kinase binding OBSOLETE. Binding to neuronal Cdc2-like kinase, an enzyme involved in the regulation of neuronal differentiation and neuro-cytoskeleton dynamics. go-plus.json neuronal Cdc2-like kinase binding http://purl.obolibrary.org/obo/GO_0042808 CHEBI:78303 biolink:ChemicalSubstance aclacinomycin S zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78303 chebi_ph7_3 GO:0042807 biolink:CellularComponent central vacuole A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination. go-plus.json http://purl.obolibrary.org/obo/GO_0042807 CHEBI:78302 biolink:ChemicalSubstance dTDP-2-deoxy-beta-L-fucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78302 chebi_ph7_3 GO:0003205 biolink:BiologicalProcess cardiac chamber development The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003205 GO:0003204 biolink:BiologicalProcess cardiac skeleton development The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. go-plus.json heart fibrous skeleton development http://purl.obolibrary.org/obo/GO_0003204 GO:0003207 biolink:BiologicalProcess cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. go-plus.json heart chamber formation http://purl.obolibrary.org/obo/GO_0003207 CHEBI:78318 biolink:ChemicalSubstance pppGp(2'->5')A(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78318 chebi_ph7_3 GO:0003206 biolink:BiologicalProcess cardiac chamber morphogenesis The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. go-plus.json heart chamber morphogenesis http://purl.obolibrary.org/obo/GO_0003206 GO:0003201 biolink:BiologicalProcess epithelial to mesenchymal transition involved in coronary vasculature morphogenesis A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature. go-plus.json http://purl.obolibrary.org/obo/GO_0003201 GO:0003200 biolink:BiologicalProcess endocardial cushion to mesenchymal transition involved in heart chamber septation A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum. go-plus.json http://purl.obolibrary.org/obo/GO_0003200 GO:0003203 biolink:BiologicalProcess endocardial cushion morphogenesis The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. go-plus.json http://purl.obolibrary.org/obo/GO_0003203 GO:0003202 biolink:BiologicalProcess endocardial cushion to mesenchymal transition involved in cardiac skeleton development A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0003202 CHEBI:112505 biolink:ChemicalSubstance 2-amino-3-hydroxy-4-methylbenzoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_112505 GO:0042813 biolink:MolecularActivity Wnt-activated receptor activity Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity. go-plus.json frizzled-2 receptor activity|frizzled receptor activity|Wnt receptor activity http://purl.obolibrary.org/obo/GO_0042813 goslim_chembl GO:0042812 biolink:BiologicalProcess pheromone catabolic process The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. go-plus.json pheromone catabolism|pheromone degradation|pheromone breakdown http://purl.obolibrary.org/obo/GO_0042812 GO:0042815 biolink:BiologicalProcess bipolar cell growth The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell. go-plus.json bipolar cell elongation|polar cell elongation|bipolar growth http://purl.obolibrary.org/obo/GO_0042815 GO:0042814 biolink:BiologicalProcess monopolar cell growth Polarized growth from one end of a cell. go-plus.json monopolar growth|polar cell elongation|monopolar cell elongation http://purl.obolibrary.org/obo/GO_0042814 GO:0042811 biolink:BiologicalProcess pheromone biosynthetic process The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. go-plus.json pheromone biosynthesis|pheromone anabolism|pheromone synthesis|pheromone formation http://purl.obolibrary.org/obo/GO_0042811 GO:0042810 biolink:BiologicalProcess pheromone metabolic process The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. go-plus.json pheromone metabolism http://purl.obolibrary.org/obo/GO_0042810 goslim_pir CHEBI:78312 biolink:ChemicalSubstance 5,10-dihydrophenazine-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78312 chebi_ph7_3 CHEBI:78311 biolink:ChemicalSubstance 15-oxolipoxin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78311 chebi_ph7_3 GO:0003209 biolink:BiologicalProcess cardiac atrium morphogenesis The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0003209 GO:0042817 biolink:BiologicalProcess pyridoxal metabolic process The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json pyridoxal metabolism http://purl.obolibrary.org/obo/GO_0042817 GO:0042816 biolink:BiologicalProcess vitamin B6 metabolic process The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. go-plus.json vitamin B6 metabolism http://purl.obolibrary.org/obo/GO_0042816 GO:0003208 biolink:BiologicalProcess cardiac ventricle morphogenesis The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003208 GO:0042819 biolink:BiologicalProcess vitamin B6 biosynthetic process The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. go-plus.json vitamin B6 biosynthesis|vitamin B6 anabolism|pyridoxine-5'-phosphate biosynthesis|vitamin B6 synthesis|vitamin B6 formation http://purl.obolibrary.org/obo/GO_0042819 CHEBI:78314 biolink:ChemicalSubstance 4-O-dimethylallyl-L-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78314 chebi_ph7_3 GO:0042818 biolink:BiologicalProcess pyridoxamine metabolic process The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. go-plus.json pyridoxamine metabolism http://purl.obolibrary.org/obo/GO_0042818 CHEBI:78313 biolink:ChemicalSubstance 5,10-dihydro-9-dimethylallylphenazine 1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78313 chebi_ph7_3 CHEBI:78329 biolink:ChemicalSubstance 13,14-dihydrolipoxin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78329 chebi_ph7_3 CHEBI:78328 biolink:ChemicalSubstance scutellarein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78328 chebi_ph7_3 CHEBI:30347 biolink:ChemicalSubstance ethylenediamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30347 CHEBI:29356 biolink:ChemicalSubstance oxide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29356 CHEBI:44992 biolink:ChemicalSubstance 2-aminopteridin-4(3H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_44992 chebi_ph7_3 GO:0042824 biolink:CellularComponent MHC class I peptide loading complex A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. go-plus.json peptide-loading complex|PLC http://purl.obolibrary.org/obo/GO_0042824 goslim_pir GO:0042823 biolink:BiologicalProcess pyridoxal phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6. MetaCyc:PWY0-845 go-plus.json pyridoxal phosphate biosynthesis|active vitamin B6 biosynthetic process|active vitamin B6 biosynthesis|pyridoxal phosphate anabolism|pyridoxal phosphate synthesis|pyridoxal phosphate formation http://purl.obolibrary.org/obo/GO_0042823 GO:0042826 biolink:MolecularActivity histone deacetylase binding Binding to histone deacetylase. go-plus.json http://purl.obolibrary.org/obo/GO_0042826 GO:0042825 biolink:CellularComponent TAP complex A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum. go-plus.json transporter associated with antigen presentation http://purl.obolibrary.org/obo/GO_0042825 CHEBI:29360 biolink:ChemicalSubstance methanediide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29360 chebi_ph7_3 GO:0042820 biolink:BiologicalProcess vitamin B6 catabolic process The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. go-plus.json vitamin B6 catabolism|vitamin B6 degradation|vitamin B6 breakdown http://purl.obolibrary.org/obo/GO_0042820 GO:0042822 biolink:BiologicalProcess pyridoxal phosphate metabolic process The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6. go-plus.json pyridoxal phosphate metabolism|active vitamin B6 metabolism|active vitamin B6 metabolic process http://purl.obolibrary.org/obo/GO_0042822 GO:0042821 biolink:BiologicalProcess pyridoxal biosynthetic process The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. go-plus.json pyridoxal biosynthesis|pyridoxal anabolism|pyridoxal synthesis|pyridoxal formation http://purl.obolibrary.org/obo/GO_0042821 CHEBI:78320 biolink:ChemicalSubstance 2-hydroxypropanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78320 CHEBI:78327 biolink:ChemicalSubstance pseudobaptigenin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78327 chebi_ph7_3 GO:0042828 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042828 GO:0042827 biolink:CellularComponent platelet dense granule Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins. go-plus.json bull's eye body|platelet dense body http://purl.obolibrary.org/obo/GO_0042827 CHEBI:78326 biolink:ChemicalSubstance 5-hydroxyxanthotoxin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78326 chebi_ph7_3 CHEBI:78325 biolink:ChemicalSubstance 13,14-dihydro-15-oxolipoxin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78325 chebi_ph7_3 CHEBI:78324 biolink:ChemicalSubstance baicalein(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78324 chebi_ph7_3 GO:0042829 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042829 CHEBI:29369 biolink:ChemicalSubstance peroxy group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29369 chebi_ph7_3 GO:0042835 biolink:MolecularActivity BRE binding Binding to a BRE RNA element (Bruno response element). go-plus.json http://purl.obolibrary.org/obo/GO_0042835 GO:0042834 biolink:MolecularActivity peptidoglycan binding Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. go-plus.json http://purl.obolibrary.org/obo/GO_0042834 GO:0042837 biolink:BiologicalProcess D-glucarate biosynthetic process The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate. go-plus.json D-glucarate biosynthesis|saccharate biosynthetic process|saccharate biosynthesis|D-glucarate anabolism|D-glucarate synthesis|D-glucarate formation http://purl.obolibrary.org/obo/GO_0042837 GO:0042836 biolink:BiologicalProcess D-glucarate metabolic process The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose. go-plus.json saccharate metabolic process|D-glucarate metabolism|saccharate metabolism http://purl.obolibrary.org/obo/GO_0042836 GO:0042831 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042831 GO:0042830 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042830 GO:0042833 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042833 GO:0042832 biolink:BiologicalProcess defense response to protozoan Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism. go-plus.json defense response to protozoan, incompatible interaction|defence response to protozoon|defense response to pathogenic protozoa|resistance response to pathogenic protozoan|resistance response to pathogenic protozoa|defence response to protozoa|defense response to protozoon|defence response to pathogenic protozoa|defense response to protozoa http://purl.obolibrary.org/obo/GO_0042832 CHEBI:30356 biolink:ChemicalSubstance isobutyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30356 chebi_ph7_3 CHEBI:30353 biolink:ChemicalSubstance isopropyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30353 chebi_ph7_3 CHEBI:78338 biolink:ChemicalSubstance wogonin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78338 chebi_ph7_3 GO:0042839 biolink:BiologicalProcess D-glucuronate metabolic process The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate. go-plus.json D-glucuronate metabolism http://purl.obolibrary.org/obo/GO_0042839 GO:0042838 biolink:BiologicalProcess D-glucarate catabolic process The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate. go-plus.json D-glucarate degradation|D-glucarate catabolism|saccharate catabolism|D-glucarate breakdown|saccharate catabolic process http://purl.obolibrary.org/obo/GO_0042838 CHEBI:29337 biolink:ChemicalSubstance azanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29337 GO:0042840 biolink:BiologicalProcess D-glucuronate catabolic process The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate. go-plus.json D-glucuronate catabolism|D-glucuronate degradation|D-glucuronate breakdown http://purl.obolibrary.org/obo/GO_0042840 GO:0042846 biolink:BiologicalProcess glycol catabolic process The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. go-plus.json dihydric alcohol catabolism|glycol degradation|glycol breakdown|glycol catabolism|dihydric alcohol catabolic process http://purl.obolibrary.org/obo/GO_0042846 GO:0042845 biolink:BiologicalProcess glycol biosynthetic process The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. go-plus.json dihydric alcohol biosynthesis|dihydric alcohol biosynthetic process|glycol anabolism|glycol biosynthesis|glycol synthesis|glycol formation http://purl.obolibrary.org/obo/GO_0042845 GO:0042848 biolink:BiologicalProcess sorbose catabolic process The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. go-plus.json sorbose catabolism|sorbose breakdown|sorbose degradation http://purl.obolibrary.org/obo/GO_0042848 GO:0042847 biolink:BiologicalProcess sorbose biosynthetic process The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. go-plus.json sorbose biosynthesis|sorbose anabolism|sorbose synthesis|sorbose formation http://purl.obolibrary.org/obo/GO_0042847 GO:0042842 biolink:BiologicalProcess D-xylose biosynthetic process The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide. go-plus.json D-xylose anabolism|D-xylose synthesis|D-xylose formation|D-xylose biosynthesis http://purl.obolibrary.org/obo/GO_0042842 CHEBI:78341 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78341 chebi_ph7_3 GO:0042841 biolink:BiologicalProcess D-glucuronate biosynthetic process The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate. go-plus.json D-glucuronate anabolism|D-glucuronate biosynthesis|D-glucuronate synthesis|D-glucuronate formation http://purl.obolibrary.org/obo/GO_0042841 CHEBI:78340 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78340 chebi_ph7_3 GO:0042844 biolink:BiologicalProcess glycol metabolic process The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. go-plus.json dihydric alcohol metabolism|dihydric alcohol metabolic process|glycol metabolism http://purl.obolibrary.org/obo/GO_0042844 GO:0042843 biolink:BiologicalProcess D-xylose catabolic process The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide. go-plus.json D-xylose catabolism|D-xylose degradation|D-xylose breakdown http://purl.obolibrary.org/obo/GO_0042843 CHEBI:44976 biolink:ChemicalSubstance phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44976 CHEBI:78345 biolink:ChemicalSubstance D-ribofuranose-2,5-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78345 chebi_ph7_3 CHEBI:30322 biolink:ChemicalSubstance 3-acetamidopropanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_30322 chebi_ph7_3 CHEBI:78343 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78343 chebi_ph7_3 CHEBI:78342 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78342 chebi_ph7_3 CHEBI:30320 biolink:ChemicalSubstance thioacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30320 chebi_ph7_3 CHEBI:78349 biolink:ChemicalSubstance 3-sulfinopropionyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78349 chebi_ph7_3 GO:0042849 biolink:BiologicalProcess L-sorbose biosynthetic process The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol. go-plus.json L-sorbose biosynthesis|L-sorbose anabolism|L-sorbose synthesis|L-sorbose formation http://purl.obolibrary.org/obo/GO_0042849 OBO:cl#lacks_plasma_membrane_part biolink:OntologyClass lacks_plasma_membrane_part lacks_plasma_membrane_part go-plus.json http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part CHEBI:78347 biolink:ChemicalSubstance 3-linalylflaviolin-2-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78347 chebi_ph7_3 CHEBI:78346 biolink:ChemicalSubstance D-ribofuranose 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78346 chebi_ph7_3 CHEBI:29348 biolink:ChemicalSubstance fatty amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29348 GO:0042851 biolink:BiologicalProcess L-alanine metabolic process The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid. go-plus.json L-alanine metabolism http://purl.obolibrary.org/obo/GO_0042851 CHEBI:44962 biolink:ChemicalSubstance D-alpha-phenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_44962 CHEBI:29347 biolink:ChemicalSubstance monocarboxylic acid amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29347 chebi_ph7_3 GO:0042850 biolink:BiologicalProcess L-sorbose catabolic process The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. go-plus.json L-sorbose catabolism|L-sorbose degradation|L-sorbose breakdown http://purl.obolibrary.org/obo/GO_0042850 CHEBI:29340 biolink:ChemicalSubstance hydridonitrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29340 CHEBI:29343 biolink:ChemicalSubstance azanediyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29343 GO:0042857 biolink:BiologicalProcess chrysobactin metabolic process The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). go-plus.json chrysobactin metabolism http://purl.obolibrary.org/obo/GO_0042857 GO:0042856 biolink:BiologicalProcess eugenol catabolic process The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil. go-plus.json eugenol degradation|eugenic acid catabolic process|eugenol breakdown|4-allyl-2-methoxyphenol catabolism|4-allyl-2-methoxyphenol catabolic process|eugenol catabolism|eugenic acid catabolism http://purl.obolibrary.org/obo/GO_0042856 GO:0042859 biolink:BiologicalProcess chrysobactin catabolic process The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). go-plus.json chrysobactin degradation|chrysobactin breakdown|chrysobactin catabolism http://purl.obolibrary.org/obo/GO_0042859 GO:0042858 biolink:BiologicalProcess chrysobactin biosynthetic process The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). go-plus.json chrysobactin biosynthetic process, peptide formation|chrysobactin anabolism|chrysobactin biosynthetic process, peptide modification|chrysobactin synthesis|chrysobactin biosynthesis|chrysobactin formation http://purl.obolibrary.org/obo/GO_0042858 CHEBI:78352 biolink:ChemicalSubstance cyclooctat-9-en-7-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78352 chebi_ph7_3 GO:0042853 biolink:BiologicalProcess L-alanine catabolic process The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid. go-plus.json L-alanine degradation|L-alanine breakdown|L-alanine catabolism http://purl.obolibrary.org/obo/GO_0042853 GO:0042852 biolink:BiologicalProcess L-alanine biosynthetic process The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid. go-plus.json L-alanine biosynthesis|L-alanine anabolism|L-alanine synthesis|L-alanine formation http://purl.obolibrary.org/obo/GO_0042852 GO:0042855 biolink:BiologicalProcess eugenol biosynthetic process The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil. go-plus.json 4-allyl-2-methoxyphenol biosynthetic process|4-allyl-2-methoxyphenol biosynthesis|eugenol anabolism|eugenol synthesis|eugenol biosynthesis|eugenol formation|eugenic acid biosynthetic process|eugenic acid biosynthesis http://purl.obolibrary.org/obo/GO_0042855 GO:0042854 biolink:BiologicalProcess eugenol metabolic process The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil. go-plus.json eugenic acid metabolic process|eugenic acid metabolism|4-allyl-2-methoxyphenol metabolic process|4-allyl-2-methoxyphenol metabolism|eugenol metabolism http://purl.obolibrary.org/obo/GO_0042854 CHEBI:78355 biolink:ChemicalSubstance 1-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78355 chebi_ph7_3 UBERON:0007329 biolink:AnatomicalEntity pancreatic duct A duct that collects and carries secretions of the exocrine pancreas to the intestine. go-plus.json ductus pancreaticus|pancreas duct|duct of pancreas http://purl.obolibrary.org/obo/UBERON_0007329 CHEBI:78358 biolink:ChemicalSubstance Delta(4)-dafachronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78358 chebi_ph7_3 CHEBI:78357 biolink:ChemicalSubstance 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78357 chebi_ph7_3 UBERON:0007324 biolink:AnatomicalEntity pancreatic lobule A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans. go-plus.json pancreas lobe|lobulus pancreaticus|pancreatic lobule http://purl.obolibrary.org/obo/UBERON_0007324 PR:000016542 biolink:Protein type 1B DNA topoisomerase 1 A protein that is a translation product of the human TOP1 gene or a 1:1 ortholog thereof. go-plus.json TOP1|DNA topoisomerase I|Top-1 http://purl.obolibrary.org/obo/PR_000016542 CHEBI:30308 biolink:ChemicalSubstance meso-2,6-diaminopimelate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30308 CHEBI:30306 biolink:ChemicalSubstance 1,3-dihydroxy-N-methylacridone go-plus.json http://purl.obolibrary.org/obo/CHEBI_30306 chebi_ph7_3 CHEBI:30305 biolink:ChemicalSubstance N-methylanthraniloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_30305 CHEBI:29317 biolink:ChemicalSubstance selanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29317 chebi_ph7_3 GO:0042860 biolink:BiologicalProcess achromobactin metabolic process The chemical reactions and pathways involving achromobactin, a citrate siderophore. go-plus.json achromobactin metabolism http://purl.obolibrary.org/obo/GO_0042860 GO:0042862 biolink:BiologicalProcess achromobactin catabolic process The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore. go-plus.json achromobactin degradation|achromobactin breakdown|achromobactin catabolism http://purl.obolibrary.org/obo/GO_0042862 CHEBI:44951 biolink:ChemicalSubstance dioxidophosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_44951 chebi_ph7_3 GO:0042861 biolink:BiologicalProcess achromobactin biosynthetic process The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore. go-plus.json achromobactin anabolism|achromobactin biosynthesis|achromobactin synthesis|achromobactin formation http://purl.obolibrary.org/obo/GO_0042861 GO:0042868 biolink:BiologicalProcess antisense RNA metabolic process The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis. go-plus.json antisense RNA metabolism http://purl.obolibrary.org/obo/GO_0042868 GO:0042867 biolink:BiologicalProcess pyruvate catabolic process The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate. go-plus.json pyruvate degradation|pyruvate breakdown|pyruvate catabolism http://purl.obolibrary.org/obo/GO_0042867 GO:0042869 biolink:BiologicalProcess aldarate transmembrane transport The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json aldarate transport http://purl.obolibrary.org/obo/GO_0042869 GO:0042864 biolink:BiologicalProcess pyochelin biosynthetic process The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). go-plus.json pyochelin anabolism|pyochelin synthesis|pyochelin formation|pyochelin biosynthetic process, peptide formation|pyochelin biosynthetic process, peptide modification|pyochelin biosynthesis http://purl.obolibrary.org/obo/GO_0042864 GO:0042863 biolink:BiologicalProcess pyochelin metabolic process The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). go-plus.json pyochelin metabolism http://purl.obolibrary.org/obo/GO_0042863 GO:0042866 biolink:BiologicalProcess pyruvate biosynthetic process The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate. go-plus.json pyruvate biosynthesis|pyruvate anabolism|pyruvate synthesis|pyruvate formation http://purl.obolibrary.org/obo/GO_0042866 CHEBI:78361 biolink:ChemicalSubstance lichen metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_78361 GO:0042865 biolink:BiologicalProcess pyochelin catabolic process The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). go-plus.json pyochelin degradation|pyochelin catabolism|pyochelin breakdown http://purl.obolibrary.org/obo/GO_0042865 CHEBI:78367 biolink:ChemicalSubstance 1-hexadecyl-2-propionyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78367 chebi_ph7_3 CHEBI:78366 biolink:ChemicalSubstance EC 2.7.1.1 (hexokinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_78366 CHEBI:78369 biolink:ChemicalSubstance 1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78369 chebi_ph7_3 CHEBI:78368 biolink:ChemicalSubstance 1-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78368 chebi_ph7_3 CHEBI:30318 biolink:ChemicalSubstance (S)-dihydrolipoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30318 CHEBI:30316 biolink:ChemicalSubstance dihydrolipoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30316 chebi_ph7_3 CHEBI:30314 biolink:ChemicalSubstance (R)-lipoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30314 CHEBI:30313 biolink:ChemicalSubstance lipoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30313 chebi_ph7_3 CHEBI:29323 biolink:ChemicalSubstance methylazoxymethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29323 chebi_ph7_3 GO:0042871 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042871 GO:0042870 biolink:BiologicalProcess D-glucarate transmembrane transport The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json D-glucarate transport http://purl.obolibrary.org/obo/GO_0042870 GO:0042873 biolink:BiologicalProcess aldonate transmembrane transport The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json aldonate transport http://purl.obolibrary.org/obo/GO_0042873 GO:0042872 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042872 GO:0042879 biolink:MolecularActivity aldonate transmembrane transporter activity Enables the transfer of aldonate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042879 CHEBI:78370 biolink:ChemicalSubstance cyclooctatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_78370 chebi_ph7_3 UBERON:0007301 biolink:AnatomicalEntity appendage blood vessel A blood vessel that is part of a limb/fin. go-plus.json fin blood vessel|limb blood vessel http://purl.obolibrary.org/obo/UBERON_0007301 UBERON:0007300 biolink:AnatomicalEntity pectoral appendage blood vessel A blood vessel that is part of a pectoral appendage. go-plus.json pectoral fin blood vessel http://purl.obolibrary.org/obo/UBERON_0007300 GO:0042878 biolink:MolecularActivity D-glucarate transmembrane transporter activity Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042878 GO:0042875 biolink:BiologicalProcess D-galactonate transmembrane transport The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json D-galactonate transport http://purl.obolibrary.org/obo/GO_0042875 GO:0042874 biolink:BiologicalProcess D-glucuronate transmembrane transport The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json D-glucuronate transport http://purl.obolibrary.org/obo/GO_0042874 GO:0042877 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042877 CHEBI:78372 biolink:ChemicalSubstance EC 3.1.1.5 (lysophospholipase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_78372 GO:0042876 biolink:MolecularActivity aldarate transmembrane transporter activity Enables the transfer of aldarate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042876 CHEBI:78371 biolink:ChemicalSubstance 1-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78371 chebi_ph7_3 CHEBI:78378 biolink:ChemicalSubstance 2-deoxy-alpha-L-fucosylaclacinomycin S zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78378 chebi_ph7_3 CHEBI:78377 biolink:ChemicalSubstance EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_78377 UBERON:0007307 biolink:AnatomicalEntity pronephric glomerular basement membrane A glomerular basement membrane that is part of a pronephros. go-plus.json pronephric glomerular filtration membrane http://purl.obolibrary.org/obo/UBERON_0007307 CHEBI:78376 biolink:ChemicalSubstance 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78376 chebi_ph7_3 UBERON:0007306 biolink:AnatomicalEntity pronephric glomerular capillary A glomerular capillary that is part of a pronephros. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007306 CHEBI:78375 biolink:ChemicalSubstance N(5)-phenyl-L-glutamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78375 chebi_ph7_3 OIO:hasScope biolink:OntologyClass has_scope go-plus.json http://www.geneontology.org/formats/oboInOwl#hasScope UBERON:0007304 biolink:AnatomicalEntity appendage vasculature A vasculature that is part of a limb/fin. go-plus.json fin vasculature http://purl.obolibrary.org/obo/UBERON_0007304 UBERON:0007303 biolink:AnatomicalEntity pharyngeal vasculature A vasculature that is part of a chordate pharynx. go-plus.json branchial vasculature http://purl.obolibrary.org/obo/UBERON_0007303 UBERON:0007302 biolink:AnatomicalEntity pectoral appendage vasculature A vasculature that is part of a pectoral appendage. go-plus.json pectoral fin vasculature http://purl.obolibrary.org/obo/UBERON_0007302 CHEBI:78379 biolink:ChemicalSubstance EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_78379 GO:0003278 biolink:BiologicalProcess apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of the heart. go-plus.json apoptosis involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0003278 GO:0003277 biolink:BiologicalProcess apoptotic process involved in endocardial cushion morphogenesis Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. go-plus.json apoptosis involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0003277 GO:0003279 biolink:BiologicalProcess cardiac septum development The progression of a cardiac septum over time, from its initial formation to the mature structure. go-plus.json heart septum development http://purl.obolibrary.org/obo/GO_0003279 GO:0003274 biolink:BiologicalProcess endocardial cushion fusion The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping. go-plus.json http://purl.obolibrary.org/obo/GO_0003274 GO:0003273 biolink:BiologicalProcess cell migration involved in endocardial cushion formation The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. go-plus.json http://purl.obolibrary.org/obo/GO_0003273 GO:0003276 biolink:BiologicalProcess apoptotic process involved in heart valve morphogenesis Any apoptotic process that contributes to the shaping of a heart valve. go-plus.json apoptosis involved in heart valve morphogenesis http://purl.obolibrary.org/obo/GO_0003276 GO:0003275 biolink:BiologicalProcess apoptotic process involved in outflow tract morphogenesis Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. go-plus.json apoptosis involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0003275 GO:0003270 biolink:BiologicalProcess Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json Notch signalling pathway involved in regulation of secondary heart field cardioblast proliferation|Notch signaling pathway involved in regulation of second heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_0003270 GO:0003272 biolink:BiologicalProcess endocardial cushion formation The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. go-plus.json http://purl.obolibrary.org/obo/GO_0003272 GO:0003271 biolink:BiologicalProcess smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation|hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation|hh signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_0003271 CHEBI:136568 biolink:ChemicalSubstance (24S)-hydroxycholesterol 3,24-disulfate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136568 chebi_ph7_3 CHEBI:136567 biolink:ChemicalSubstance (24S)-hydroxycholesterol 3-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136567 chebi_ph7_3 CHEBI:136566 biolink:ChemicalSubstance (24S)-hydroxycholesterol 24-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136566 chebi_ph7_3 CHEBI:136565 biolink:ChemicalSubstance (6R)-6-lactoyl-5,6,7,8-tetrahydropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_136565 chebi_ph7_3 GO:0198738 biolink:BiologicalProcess cell-cell signaling by wnt Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell. go-plus.json http://purl.obolibrary.org/obo/GO_0198738 CHEBI:136569 biolink:ChemicalSubstance (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136569 CHEBI:136560 biolink:ChemicalSubstance (4aR,10bS)-noroxomaritidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136560 CHEBI:136564 biolink:ChemicalSubstance (R)-dyspropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_136564 chebi_ph7_3 CHEBI:136563 biolink:ChemicalSubstance (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136563 CHEBI:136562 biolink:ChemicalSubstance long-chain fatty acyl-AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136562 chebi_ph7_3 GO:0003289 biolink:BiologicalProcess atrial septum primum morphogenesis The process in which anatomical structure of an atrial septum primum is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003289 GO:0003288 biolink:BiologicalProcess ventricular septum intermedium morphogenesis The developmental process in which a ventricular septum intermedium is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003288 GO:0003285 biolink:BiologicalProcess septum secundum development The progression of the septum secundum over time, from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003285 GO:0003284 biolink:BiologicalProcess septum primum development The progression of the septum primum over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003284 GO:0003287 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003287 GO:0003286 biolink:BiologicalProcess atrial septum intermedium development The progression of the atrial septum intermedium over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003286 GO:0003281 biolink:BiologicalProcess ventricular septum development The progression of the ventricular septum over time from its formation to the mature structure. go-plus.json interventricular septum development|septum inferius development http://purl.obolibrary.org/obo/GO_0003281 GO:0003280 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003280 GO:0003283 biolink:BiologicalProcess atrial septum development The progression of the atrial septum over time, from its initial formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003283 GO:0003282 biolink:BiologicalProcess ventricular septum intermedium development The progression of the ventricular septum intermedium over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003282 CHEBI:136579 biolink:ChemicalSubstance cholesterol sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136579 chebi_ph7_3 GO:0003290 biolink:BiologicalProcess atrial septum secundum morphogenesis The process in which anatomical structure of an atrial septum secundum is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003290 CHEBI:136576 biolink:ChemicalSubstance (7Z,10Z,16Z,19Z)-13,14-epoxydocosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136576 CHEBI:136570 biolink:ChemicalSubstance (6R)-5,6,7,8-tetrahydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_136570 chebi_ph7_3 CHEBI:136575 biolink:ChemicalSubstance (7Z,10Z,13Z,19Z)-16,17-epoxydocosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136575 CHEBI:136574 biolink:ChemicalSubstance epoxydocosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136574 CHEBI:136573 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-19,20-epoxydocosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136573 CHEBI:136572 biolink:ChemicalSubstance (6R)-5,10-methylenetetrahydrofolate poly(gamma-L-glutamate) macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_136572 chebi_ph7_3 GO:0003259 biolink:BiologicalProcess cardioblast anterior-lateral migration The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0003259 GO:0003256 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003256 GO:0003255 biolink:BiologicalProcess endocardial precursor cell differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate. go-plus.json http://purl.obolibrary.org/obo/GO_0003255 GO:0003258 biolink:BiologicalProcess regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003258 GO:0003257 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003257 GO:0003252 biolink:BiologicalProcess negative regulation of cell proliferation involved in heart valve morphogenesis Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. go-plus.json http://purl.obolibrary.org/obo/GO_0003252 GO:0003251 biolink:BiologicalProcess positive regulation of cell proliferation involved in heart valve morphogenesis Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. go-plus.json http://purl.obolibrary.org/obo/GO_0003251 GO:0003254 biolink:BiologicalProcess regulation of membrane depolarization Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive. go-plus.json http://purl.obolibrary.org/obo/GO_0003254 GO:0003253 biolink:BiologicalProcess cardiac neural crest cell migration involved in outflow tract morphogenesis The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. go-plus.json http://purl.obolibrary.org/obo/GO_0003253 GO:0003250 biolink:BiologicalProcess regulation of cell proliferation involved in heart valve morphogenesis Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. go-plus.json http://purl.obolibrary.org/obo/GO_0003250 CHEBI:136545 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136545 chebi_ph7_3 CHEBI:136544 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_136544 chebi_ph7_3 CHEBI:136543 biolink:ChemicalSubstance (+)-sesamin dicatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136543 chebi_ph7_3 CHEBI:136542 biolink:ChemicalSubstance (+)-sesamin monocatechol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136542 chebi_ph7_3 CHEBI:136541 biolink:ChemicalSubstance (R)-2-(phosphonomethyl)malate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136541 chebi_ph7_3 GO:0003267 biolink:BiologicalProcess canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json canonical Wnt receptor signalling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of second heart field cardioblast proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_0003267 GO:0003266 biolink:BiologicalProcess regulation of secondary heart field cardioblast proliferation Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract). go-plus.json regulation of second heart field cardioblast proliferation|regulation of SHF cardioblast proliferation http://purl.obolibrary.org/obo/GO_0003266 GO:0003269 biolink:BiologicalProcess BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json BMP signalling pathway involved in regulation of secondary heart field cardioblast proliferation|BMP signaling pathway involved in regulation of second heart field cardioblast proliferation http://purl.obolibrary.org/obo/GO_0003269 GO:0003268 biolink:BiologicalProcess fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json fibroblast growth factor receptor signalling pathway involved in regulation of secondary heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of second heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast cell proliferation http://purl.obolibrary.org/obo/GO_0003268 GO:0003263 biolink:BiologicalProcess cardioblast proliferation The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0003263 GO:0003262 biolink:BiologicalProcess endocardial progenitor cell migration to the midline involved in heart field formation The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003262 GO:0003265 biolink:BiologicalProcess regulation of primary heart field cardioblast proliferation Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle. go-plus.json regulation of FHF cardioblast proliferation|regulation of first heart field cardioblast proliferation|regulation of first heart field cardiac proliferation http://purl.obolibrary.org/obo/GO_0003265 GO:0003264 biolink:BiologicalProcess regulation of cardioblast proliferation Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0003264 GO:0003261 biolink:BiologicalProcess cardiac muscle progenitor cell migration to the midline involved in heart field formation The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart. go-plus.json myocardial progenitor cell midline convergence http://purl.obolibrary.org/obo/GO_0003261 GO:0003260 biolink:BiologicalProcess cardioblast migration The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0003260 CHEBI:136557 biolink:ChemicalSubstance (4aS,10bR)-noroxomaritidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136557 GO:0003238 biolink:BiologicalProcess conus arteriosus development The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. go-plus.json http://purl.obolibrary.org/obo/GO_0003238 GO:0003237 biolink:BiologicalProcess sinus venosus formation The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003237 GO:0003239 biolink:BiologicalProcess conus arteriosus morphogenesis The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. go-plus.json http://purl.obolibrary.org/obo/GO_0003239 GO:0003234 biolink:BiologicalProcess bulbus arteriosus formation The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003234 GO:0003233 biolink:BiologicalProcess bulbus arteriosus morphogenesis The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber. go-plus.json http://purl.obolibrary.org/obo/GO_0003233 GO:0003236 biolink:BiologicalProcess sinus venosus morphogenesis The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003236 GO:0003235 biolink:BiologicalProcess sinus venosus development The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003235 GO:0003230 biolink:BiologicalProcess cardiac atrium development The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0003230 GO:0003232 biolink:BiologicalProcess bulbus arteriosus development The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber. go-plus.json http://purl.obolibrary.org/obo/GO_0003232 GO:0003231 biolink:BiologicalProcess cardiac ventricle development The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003231 NCBITaxon:777 biolink:OrganismalEntity Coxiella burnetii go-plus.json Rickettsia diaporica|Rickettsia burneti http://purl.obolibrary.org/obo/NCBITaxon_777 NCBITaxon:776 biolink:OrganismalEntity Coxiella go-plus.json Coxiella|Burnetia http://purl.obolibrary.org/obo/NCBITaxon_776 CHEBI:136524 biolink:ChemicalSubstance 13-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136524 chebi_ph7_3 CHEBI:136523 biolink:ChemicalSubstance 7-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136523 chebi_ph7_3 CHEBI:136522 biolink:ChemicalSubstance (9Z,12Z)-11-hydroxyoctadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136522 chebi_ph7_3 CHEBI:136521 biolink:ChemicalSubstance roseoflavin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136521 chebi_ph7_3 CHEBI:68946 biolink:ChemicalSubstance alpha-dimorphecolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68946 CHEBI:68947 biolink:ChemicalSubstance 13-oxo-9Z,11E-ODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_68947 CHEBI:136520 biolink:ChemicalSubstance 8-demethyl-8-(methylamino)riboflavin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136520 chebi_ph7_3 GO:0003249 biolink:BiologicalProcess cell proliferation involved in heart valve morphogenesis The multiplication or reproduction of cells that contributes to the shaping of a heart valve. go-plus.json http://purl.obolibrary.org/obo/GO_0003249 GO:0003248 biolink:BiologicalProcess heart capillary growth The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0003248 GO:0003245 biolink:BiologicalProcess cardiac muscle tissue growth involved in heart morphogenesis The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003245 GO:0003244 biolink:BiologicalProcess radial growth involved in right ventricle morphogenesis The morphogenic growth in which the right ventricle grows along a radial axis. go-plus.json http://purl.obolibrary.org/obo/GO_0003244 GO:0003247 biolink:BiologicalProcess post-embryonic cardiac muscle cell growth involved in heart morphogenesis The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003247 GO:0003246 biolink:BiologicalProcess embryonic cardiac muscle cell growth involved in heart morphogenesis The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart. go-plus.json embryonic cardiac muscle physiological hypertrophy http://purl.obolibrary.org/obo/GO_0003246 GO:0003241 biolink:BiologicalProcess growth involved in heart morphogenesis Developmental growth that contributes to the shaping of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003241 GO:0003240 biolink:BiologicalProcess conus arteriosus formation The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. go-plus.json http://purl.obolibrary.org/obo/GO_0003240 NCBITaxon:136841 biolink:OrganismalEntity Pseudomonas aeruginosa group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_136841 GO:0003243 biolink:BiologicalProcess circumferential growth involved in left ventricle morphogenesis The morphogenetic growth in which the left ventricle grows expanding its external boundary. go-plus.json http://purl.obolibrary.org/obo/GO_0003243 GO:0003242 biolink:BiologicalProcess cardiac chamber ballooning The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping. go-plus.json http://purl.obolibrary.org/obo/GO_0003242 CHEBI:136531 biolink:ChemicalSubstance 13-oxo-9,11-octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136531 GO:0003216 biolink:BiologicalProcess cardiac left atrium formation The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0003216 GO:0003215 biolink:BiologicalProcess cardiac right ventricle morphogenesis The process in which the right cardiac ventricle is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003215 GO:0003218 biolink:BiologicalProcess cardiac left ventricle formation The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0003218 GO:0003217 biolink:BiologicalProcess cardiac right atrium formation The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0003217 GO:0003212 biolink:BiologicalProcess cardiac left atrium morphogenesis The process in which the left cardiac atrium is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003212 GO:0003211 biolink:BiologicalProcess cardiac ventricle formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003211 GO:0003214 biolink:BiologicalProcess cardiac left ventricle morphogenesis The process in which the left cardiac ventricle is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003214 GO:0003213 biolink:BiologicalProcess cardiac right atrium morphogenesis The process in which the right cardiac atrium is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003213 CHEBI:136509 biolink:ChemicalSubstance biliverdin beta(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136509 chebi_ph7_3 GO:0003210 biolink:BiologicalProcess cardiac atrium formation The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. go-plus.json http://purl.obolibrary.org/obo/GO_0003210 CHEBI:136508 biolink:ChemicalSubstance mycobilin b(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136508 chebi_ph7_3 CHEBI:136507 biolink:ChemicalSubstance mycobilin a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136507 chebi_ph7_3 CHEBI:29396 biolink:ChemicalSubstance disulfide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29396 CHEBI:136505 biolink:ChemicalSubstance homocysteine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_136505 GO:0003219 biolink:BiologicalProcess cardiac right ventricle formation The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0003219 GO:0003227 biolink:BiologicalProcess right ventricular trabecular myocardium morphogenesis The process in which the anatomical structures of the right ventricular myocardium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003227 GO:0003226 biolink:BiologicalProcess right ventricular compact myocardium morphogenesis The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003226 GO:0003229 biolink:BiologicalProcess ventricular cardiac muscle tissue development The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. go-plus.json ventricular myocardium development http://purl.obolibrary.org/obo/GO_0003229 GO:0003228 biolink:BiologicalProcess atrial cardiac muscle tissue development The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. go-plus.json atrial myocardium development http://purl.obolibrary.org/obo/GO_0003228 GO:0003223 biolink:BiologicalProcess ventricular compact myocardium morphogenesis The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003223 GO:0003222 biolink:BiologicalProcess ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. go-plus.json trabecula carnea morphogenesis http://purl.obolibrary.org/obo/GO_0003222 GO:0003225 biolink:BiologicalProcess left ventricular trabecular myocardium morphogenesis The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003225 GO:0003224 biolink:BiologicalProcess left ventricular compact myocardium morphogenesis The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003224 GO:0003221 biolink:BiologicalProcess right ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. go-plus.json right ventricle myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003221 CHEBI:136518 biolink:ChemicalSubstance 8-amino-8-demethylriboflavin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136518 chebi_ph7_3 GO:0003220 biolink:BiologicalProcess left ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. go-plus.json left ventricular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003220 CHEBI:136513 biolink:ChemicalSubstance 7,7-dihydroxybacteriochlorophyllide c(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136513 chebi_ph7_3 CHEBI:136512 biolink:ChemicalSubstance bacteriochlorophyllide e(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136512 chebi_ph7_3 CHEBI:136511 biolink:ChemicalSubstance manganese dioxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136511 chebi_ph7_3 CHEBI:136510 biolink:ChemicalSubstance biliverdin delta(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136510 chebi_ph7_3 CHEBI:136517 biolink:ChemicalSubstance anaerobilin dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136517 chebi_ph7_3 CHEBI:136516 biolink:ChemicalSubstance gramine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136516 chebi_ph7_3 CHEBI:136515 biolink:ChemicalSubstance 3-(methylaminomethyl)indole(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136515 chebi_ph7_3 CHEBI:136514 biolink:ChemicalSubstance indol-3-ylmethylamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136514 chebi_ph7_3 CHEBI:30395 biolink:ChemicalSubstance acetylacetonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30395 CL:1000692 biolink:Cell kidney interstitial fibroblast go-plus.json http://purl.obolibrary.org/obo/CL_1000692 CHEBI:8934 biolink:ChemicalSubstance (4-bromophenylsulfanyl)pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_8934 CHEBI:8944 biolink:ChemicalSubstance S-adenosyl-4-methylthio-2-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_8944 NCBITaxon:712 biolink:OrganismalEntity Pasteurellaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_712 CHEBI:136589 biolink:ChemicalSubstance N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136589 chebi_ph7_3 CHEBI:136588 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_136588 chebi_ph7_3 CHEBI:136587 biolink:ChemicalSubstance (4Z,7Z,11Z,13Z,15E,17S,19Z)-10,17-bis(hydroperoxy)docosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136587 CHEBI:136582 biolink:ChemicalSubstance 17beta-estradiol 3-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136582 chebi_ph7_3 CHEBI:136581 biolink:ChemicalSubstance 2-hydroxy-(indol-3-yl)acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136581 CHEBI:136584 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-20-hydroxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136584 CHEBI:136583 biolink:ChemicalSubstance (7Z,13Z,16Z,19Z)-10,11-epoxydocosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136583 NCBITaxon:727 biolink:OrganismalEntity Haemophilus influenzae go-plus.json Influenza-bacillus|Haemophilus meningitidis|Coccobacillus pfeifferi|Bacterium influenzae|Mycobacterium influenzae http://purl.obolibrary.org/obo/NCBITaxon_727 NCBITaxon:724 biolink:OrganismalEntity Haemophilus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_724 CHEBI:136599 biolink:ChemicalSubstance 3-amino-D-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136599 chebi_ph7_3 CHEBI:136598 biolink:ChemicalSubstance 3-amino-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136598 CHEBI:136593 biolink:ChemicalSubstance (R)-2-hydroxy-3-oxo-4-(phosphonatooxy)butanoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136593 chebi_ph7_3 CHEBI:136592 biolink:ChemicalSubstance (S)-2-hydroxy-3-oxo-4-(phosphonatooxy)butanoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136592 chebi_ph7_3 CHEBI:136591 biolink:ChemicalSubstance D-erythronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136591 chebi_ph7_3 CHEBI:136590 biolink:ChemicalSubstance 4-O-phosphonato-D-threonate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136590 chebi_ph7_3 CHEBI:136597 biolink:ChemicalSubstance 12-oxo-6-trans-leukotriene B4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_136597 CHEBI:136596 biolink:ChemicalSubstance 4-hydroxy monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136596 chebi_ph7_3 CHEBI:136595 biolink:ChemicalSubstance (7Z,11Z,13Z,15E,19Z)-10,17-bis(hydroperoxy)docosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136595 CHEBI:8984 biolink:ChemicalSubstance sodium dodecyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_8984 CHEBI:136594 biolink:ChemicalSubstance (4Z,7Z,11Z,13Z,15E,17S)-10,17-bis(hydroperoxy)docosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136594 GO:0052326 biolink:BiologicalProcess obsolete interaction with symbiont via protein secreted by type IV secretion system OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type IV secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json interaction with symbiont via protein secreted by type IV secretion system http://purl.obolibrary.org/obo/GO_0052326 GO:0052325 biolink:BiologicalProcess cell wall pectin biosynthetic process The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall. go-plus.json cell wall pectin biosynthesis|pectin biosynthesis during cell wall organization and biogenesis http://purl.obolibrary.org/obo/GO_0052325 GO:0052324 biolink:BiologicalProcess plant-type cell wall cellulose biosynthetic process The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall. go-plus.json cellulose biosynthesis during cell wall biosynthesis|cell wall cellulose biosynthesis http://purl.obolibrary.org/obo/GO_0052324 GO:0052323 biolink:BiologicalProcess negative regulation of phytoalexin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins. go-plus.json down-regulation of phytoalexin biosynthesis|negative regulation of phytoalexin biosynthesis|downregulation of phytoalexin biosynthesis|down regulation of phytoalexin biosynthesis|inhibition of phytoalexin biosynthesis http://purl.obolibrary.org/obo/GO_0052323 CHEBI:20960 biolink:ChemicalSubstance galactose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20960 GO:0052329 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052329 GO:0052328 biolink:BiologicalProcess obsolete interaction with symbiont via protein secreted by type III secretion system OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type III secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json interaction with symbiont via protein secreted by type III secretion system http://purl.obolibrary.org/obo/GO_0052328 GO:0052327 biolink:BiologicalProcess obsolete interaction with symbiont via protein secreted by type II secretion system OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type II secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json interaction with symbiont via protein secreted by type II secretion system http://purl.obolibrary.org/obo/GO_0052327 CHEBI:20961 biolink:ChemicalSubstance D-galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_20961 CL:1000618 biolink:Cell juxtaglomerular complex cell go-plus.json juxtaglomerulus cell http://purl.obolibrary.org/obo/CL_1000618 CL:1000617 biolink:Cell kidney inner medulla cell go-plus.json http://purl.obolibrary.org/obo/CL_1000617 CL:1000616 biolink:Cell kidney outer medulla cell go-plus.json http://purl.obolibrary.org/obo/CL_1000616 CL:1000615 biolink:Cell kidney cortex tubule cell go-plus.json http://purl.obolibrary.org/obo/CL_1000615 CL:1000612 biolink:Cell kidney corpuscule cell go-plus.json http://purl.obolibrary.org/obo/CL_1000612 CHEBI:78260 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78260 chebi_ph7_3 UBERON:0007376 biolink:AnatomicalEntity outer epithelium The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. go-plus.json hypoderm|epidermis|outer epithelial layer|outer epidermal layer|hypodermis|epidermis (sensu Metazoa) http://purl.obolibrary.org/obo/UBERON_0007376 UBERON:0007375 biolink:AnatomicalEntity roof of mouth A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones. go-plus.json roof of oral cavity|palatum|primary or secondary palate|roof of buccal cavity|palate http://purl.obolibrary.org/obo/UBERON_0007375 CHEBI:78264 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78264 chebi_ph7_3 UBERON:0007373 biolink:AnatomicalEntity inferior surface of tongue The lower (inferior) side of the tongue. go-plus.json ventral surface of tongue|ventrum linguae http://purl.obolibrary.org/obo/UBERON_0007373 CHEBI:78263 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78263 chebi_ph7_3 CHEBI:78262 biolink:ChemicalSubstance 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78262 chebi_ph7_3 UBERON:0007371 biolink:AnatomicalEntity superior surface of tongue The upper (superior) side of the tongue. go-plus.json dorsal surface of tongue http://purl.obolibrary.org/obo/UBERON_0007371 CHEBI:78261 biolink:ChemicalSubstance 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78261 chebi_ph7_3 CHEBI:78268 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78268 chebi_ph7_3 CHEBI:78267 biolink:ChemicalSubstance 3-deoxy-D-threo-hex-2-ulosarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78267 chebi_ph7_3 CHEBI:78266 biolink:ChemicalSubstance 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78266 chebi_ph7_3 CHEBI:78265 biolink:ChemicalSubstance 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78265 chebi_ph7_3 GO:0052322 biolink:BiologicalProcess positive regulation of phytoalexin biosynthetic process Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins. go-plus.json activation of phytoalexin biosynthesis|up-regulation of phytoalexin biosynthesis|positive regulation of phytoalexin biosynthesis|up regulation of phytoalexin biosynthesis|upregulation of phytoalexin biosynthesis|stimulation of phytoalexin biosynthesis http://purl.obolibrary.org/obo/GO_0052322 CHEBI:19960 biolink:ChemicalSubstance 3-amino-3-(4-hydroxyphenyl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19960 GO:0052321 biolink:BiologicalProcess negative regulation of phytoalexin metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins. go-plus.json down-regulation of phytoalexin metabolism|negative regulation of phytoalexin metabolism|downregulation of phytoalexin metabolism|down regulation of phytoalexin metabolism|inhibition of phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0052321 GO:0052320 biolink:BiologicalProcess positive regulation of phytoalexin metabolic process Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins. go-plus.json stimulation of phytoalexin metabolism|up-regulation of phytoalexin metabolism|activation of phytoalexin metabolism|up regulation of phytoalexin metabolism|positive regulation of phytoalexin metabolism|upregulation of phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0052320 CHEBI:78269 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78269 chebi_ph7_3 UBERON:0007379 biolink:AnatomicalEntity shelled egg The hard-shelled reproductive body produced by a bird (especially by the common domestic chicken) or a reptile; also: its contents used as food. go-plus.json egg http://purl.obolibrary.org/obo/UBERON_0007379 GO:0052337 biolink:BiologicalProcess modification by host of symbiont membrane The process in which an organism effects a change in the structure or function of a symbiont cellular membrane. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modification by host of symbiont cell membrane http://purl.obolibrary.org/obo/GO_0052337 GO:0052336 biolink:BiologicalProcess modification by host of symbiont cell wall The process in which an organism effects a change in the structure or function of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json metabolism of symbiont cell wall by organism http://purl.obolibrary.org/obo/GO_0052336 GO:0052335 biolink:BiologicalProcess modification by host of symbiont cytoskeleton The process in which an organism effects a change in the structure or function of the symbiont cytoskeleton. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052335 GO:0052334 biolink:BiologicalProcess modification by organism of cytoskeleton of other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or function of the cytoskeleton of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modification by organism of cytoskeleton of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052334 GO:0160003 biolink:MolecularActivity mono-ADP-D-ribose modification-dependent protein binding Binding to a protein upon mono-ADP-ribosylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0160003 CHEBI:20971 biolink:ChemicalSubstance D-galactosyl-N-acetyl-D-glucosaminyl-(1->3)-D-galactosyl-(1->4)-D-glucosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_20971 GO:0160002 biolink:MolecularActivity ADP-D-ribose modification-dependent protein binding Binding to a protein upon ADP-ribosylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0160002 GO:0052339 biolink:BiologicalProcess disruption by organism of cell wall of other organism involved in symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json disassembly by organism of cell wall of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052339 GO:0052338 biolink:BiologicalProcess disruption by host of symbiont cell wall The chemical reactions and pathways performed by an organism resulting in the breakdown of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json catabolism of symbiont cell wall by organism|disassembly by host of symbiont cell wall|degradation of symbiont cell wall by organism http://purl.obolibrary.org/obo/GO_0052338 GO:0160004 biolink:MolecularActivity poly-ADP-D-ribose modification-dependent protein binding Binding to a protein upon poly-ADP-ribosylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0160004 CL:1000606 biolink:Cell kidney nerve cell go-plus.json http://purl.obolibrary.org/obo/CL_1000606 PR:000002094 biolink:Protein C-C motif chemokine 5 A C/C-C motif small inducible chemokine that is a translation product of the human CCL5 gene or a 1:1 ortholog thereof. go-plus.json TCP228|EoCP|D17S136E|T cell-specific protein P228|small inducible cytokine A5|eosinophil chemotactic cytokine|CCL5|SIS-delta|small-inducible cytokine A5|RANTES|T-cell-specific protein RANTES|SCYA5 http://purl.obolibrary.org/obo/PR_000002094 CL:1000601 biolink:Cell ureteral cell go-plus.json http://purl.obolibrary.org/obo/CL_1000601 UBERON:0007367 biolink:AnatomicalEntity surface of tongue An anatomical surface that is part of a tongue. go-plus.json tongue surface http://purl.obolibrary.org/obo/UBERON_0007367 CHEBI:78270 biolink:ChemicalSubstance 2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78270 CHEBI:78275 biolink:ChemicalSubstance N(5)-hydroxy-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78275 chebi_ph7_3 CHEBI:78274 biolink:ChemicalSubstance ferruginol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78274 chebi_ph7_3 CHEBI:78273 biolink:ChemicalSubstance 9-cis-retinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_78273 chebi_ph7_3 CHEBI:78272 biolink:ChemicalSubstance 9-cis-retinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78272 chebi_ph7_3 CHEBI:78279 biolink:ChemicalSubstance lysophosphatidate 18:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78279 chebi_ph7_3 CHEBI:78278 biolink:ChemicalSubstance omega-hydroxymenaquinone-4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78278 chebi_ph7_3 GO:0160001 biolink:BiologicalProcess extrasynaptic signaling via GABA Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid. go-plus.json http://purl.obolibrary.org/obo/GO_0160001 CHEBI:78277 biolink:ChemicalSubstance menaquinone-4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78277 chebi_ph7_3 CHEBI:78276 biolink:ChemicalSubstance omega-hydroxyphylloquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_78276 chebi_ph7_3 CHEBI:19950 biolink:ChemicalSubstance 3-O-methylgallate go-plus.json http://purl.obolibrary.org/obo/CHEBI_19950 chebi_ph7_3 GO:0052333 biolink:BiologicalProcess modification by organism of cell wall of other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of cell wall of other organism|modification by organism of cell wall of other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052333 GO:0052332 biolink:BiologicalProcess modification by organism of membrane in other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or function of a cellular membrane of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modification by organism of cell membrane in other organism during symbiotic interaction|modification by organism of cell membrane in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052332 GO:0052331 biolink:BiologicalProcess hemolysis in other organism involved in symbiotic interaction The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another, where two organisms are in a symbiotic interaction. go-plus.json hemolysis of cells in other organism involved in symbiotic interaction|hemolysin activity|haemolysis in other organism involved in symbiotic interaction|hemolysis of cells in other organism during symbiotic interaction|hemolysis by organism of RBCs in other organism during symbiotic interaction|hemolysis by organism of erythrocytes in other organism during symbiotic interaction|hemolysis by organism of red blood cells in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052331 GO:0052330 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052330 GO:0052348 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052348 GO:0052347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052347 GO:0052346 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont nitric oxide production OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related symbiont nitric oxide production|positive regulation by organism of defense-related symbiont NO production http://purl.obolibrary.org/obo/GO_0052346 GO:0052345 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052345 GO:0052349 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont reactive oxygen species production OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related symbiont metabolic burst|positive regulation by organism of defense-related symbiont ROI production|positive regulation by organism of defense-related symbiont respiratory burst|positive regulation by organism of defense-related symbiont ROS production|positive regulation by organism of defense-related symbiont active oxygen species production|positive regulation by organism of defense-related symbiont reactive oxygen intermediate production|positive regulation by organism of defense-related symbiont reactive oxidative species production|positive regulation by organism of defense-related symbiont oxidative burst|positive regulation by organism of defense-related symbiont reactive oxygen species production|positive regulation by organism of defense-related symbiont AOS production http://purl.obolibrary.org/obo/GO_0052349 CHEBI:78282 biolink:ChemicalSubstance 2-hydroxy-7-methoxy-5-methyl-1-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78282 chebi_ph7_3 CHEBI:78281 biolink:ChemicalSubstance 2,7-dihydroxy-5-methyl-1-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78281 chebi_ph7_3 CHEBI:78286 biolink:ChemicalSubstance 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)tetracenomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_78286 chebi_ph7_3 CHEBI:78285 biolink:ChemicalSubstance 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_78285 chebi_ph7_3 CHEBI:78283 biolink:ChemicalSubstance 8-demethyl-8-(alpha-L-rhamnosyl)tetracenomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_78283 chebi_ph7_3 GO:0052340 biolink:BiologicalProcess obsolete catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of cell wall cellulose in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052340 CHEBI:78287 biolink:ChemicalSubstance 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)tetracenomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_78287 chebi_ph7_3 GO:0052344 biolink:BiologicalProcess positive regulation by symbiont of host phytoalexin production Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json up regulation by symbiont of host phytoalexin production|activation by symbiont of host phytoalexin production|stimulation by symbiont of host phytoalexin production|positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction|up-regulation by symbiont of host phytoalexin production|upregulation by symbiont of host phytoalexin production http://purl.obolibrary.org/obo/GO_0052344 CHEBI:19982 biolink:ChemicalSubstance 3-chloroacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19982 GO:0052343 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont phytoalexin production OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of symbiont phytoalexin production http://purl.obolibrary.org/obo/GO_0052343 GO:0052342 biolink:BiologicalProcess obsolete catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of cell wall chitin in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052342 GO:0052341 biolink:BiologicalProcess obsolete catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of cell wall pectin in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052341 GO:0052359 biolink:BiologicalProcess obsolete catabolism by organism of glucan in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of glucan in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052359 GO:0052358 biolink:BiologicalProcess obsolete catabolism by host of symbiont glucan OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052358 GO:0052357 biolink:BiologicalProcess obsolete catabolism by host of symbiont cell wall pectin OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052357 GO:0052356 biolink:BiologicalProcess obsolete catabolism by host of symbiont cell wall chitin OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052356 CHEBI:78293 biolink:ChemicalSubstance ophiobolin F go-plus.json http://purl.obolibrary.org/obo/CHEBI_78293 chebi_ph7_3 PR:000002065 biolink:Protein mast/stem cell growth factor receptor A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof. go-plus.json SCFR|KIT|CD117|Sl|tyrosine-protein kinase Kit|proto-oncogene c-Kit http://purl.obolibrary.org/obo/PR_000002065 CHEBI:78290 biolink:ChemicalSubstance L-m-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78290 chebi_ph7_3 CHEBI:78297 biolink:ChemicalSubstance (3S)-3-ammonio-3-(3-chloro-4-hydroxyphenyl)propanoyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78297 chebi_ph7_3 CHEBI:78296 biolink:ChemicalSubstance (3S)-3-ammonio-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78296 chebi_ph7_3 CHEBI:78295 biolink:ChemicalSubstance food component go-plus.json http://purl.obolibrary.org/obo/CHEBI_78295 CHEBI:78294 biolink:ChemicalSubstance (3R)-3-hydroxy-L-argininium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78294 chebi_ph7_3 GO:0052351 biolink:BiologicalProcess obsolete induction by organism of systemic acquired resistance in symbiont OBSOLETE. Any process in which an organism activates systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of systemic acquired resistance in symbiont|activation by organism of systemic acquired resistance in symbiont|activation by organism of SAR in symbiont|induction by organism of SAR in symbiont http://purl.obolibrary.org/obo/GO_0052351 GO:0052350 biolink:BiologicalProcess obsolete induction by organism of induced systemic resistance in symbiont OBSOLETE. Any process in which an organism activates induced systemic resistance in the symbiont; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of induced systemic resistance in symbiont|activation by organism of ISR in symbiont|induction by organism of ISR in symbiont|activation by organism of induced systemic resistance in symbiont http://purl.obolibrary.org/obo/GO_0052350 CHEBI:78299 biolink:ChemicalSubstance environmental food contaminant go-plus.json http://purl.obolibrary.org/obo/CHEBI_78299 CHEBI:20954 biolink:ChemicalSubstance D-galactosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_20954 CHEBI:78298 biolink:ChemicalSubstance environmental contaminant go-plus.json http://purl.obolibrary.org/obo/CHEBI_78298 GO:0052355 biolink:BiologicalProcess obsolete catabolism by host of symbiont cell wall cellulose OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052355 GO:0052354 biolink:BiologicalProcess obsolete catabolism by organism of carbohydrate in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of carbohydrate in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052354 GO:0052353 biolink:BiologicalProcess obsolete catabolism by host of symbiont carbohydrate OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052353 GO:0052352 biolink:BiologicalProcess obsolete biosynthesis by host of substance in symbiont OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the formation of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052352 GO:0052369 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052369 GO:0052368 biolink:BiologicalProcess disruption by organism of cellular component in other organism involved in symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism of cellular component in other organism|catabolism of structural constituent in other organism|disassembly by organism of cellular component in other organism involved in symbiotic interaction|disassembly by organism of cellular component in other organism during symbiotic interaction|degradation of cellular component in other organism http://purl.obolibrary.org/obo/GO_0052368 GO:0052367 biolink:BiologicalProcess disruption by host of symbiont cellular component The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json disassembly by host of symbiont cellular component|degradation of symbiont cellular component by organism|catabolism of symbiont cellular component by organism|catabolism of symbiont structural constituent by organism http://purl.obolibrary.org/obo/GO_0052367 NCBITaxon:171101 biolink:OrganismalEntity Streptococcus pneumoniae R6 go-plus.json Streptococcus pneumoniae str. R6|Streptococcus pneumoniae (strain ATCC BAA-255 / R6) http://purl.obolibrary.org/obo/NCBITaxon_171101 CHEBI:19929 biolink:ChemicalSubstance 3-hydroxy-3-phenylpropionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19929 GO:0052362 biolink:BiologicalProcess obsolete catabolism by host of symbiont protein OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052362 GO:0052361 biolink:BiologicalProcess obsolete catabolism by organism of macromolecule in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of macromolecule in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052361 GO:0052360 biolink:BiologicalProcess obsolete catabolism by host of symbiont macromolecule OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052360 GO:0052366 biolink:BiologicalProcess obsolete catabolism by organism of xylan in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of xylan in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052366 GO:0052365 biolink:BiologicalProcess obsolete catabolism by host of symbiont xylan OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052365 GO:0052364 biolink:BiologicalProcess obsolete catabolism by host of substance in symbiont OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the breakdown of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052364 GO:0052363 biolink:BiologicalProcess obsolete catabolism by organism of protein in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the second organism, where the two organisms are in a symbiotic interaction. go-plus.json catabolism by organism of protein in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052363 GO:0052379 biolink:BiologicalProcess obsolete modulation by organism of entry into other organism via phagocytosis involved in symbiotic interaction OBSOLETE. Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism via the phagocytotic processes of the other organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation by organism of entry into other organism via phagocytosis during symbiotic interaction|modulation by organism of entry into other organism via other organism phagocytosis during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052379 GO:0052378 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052378 GO:0052373 biolink:BiologicalProcess suppression of symbiont entry into host by host Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction. go-plus.json downregulation by organism of entry into other organism during symbiotic interaction|inhibition by organism of entry into other organism during symbiotic interaction|down regulation by organism of entry into other organism during symbiotic interaction|negative regulation by organism of entry into other organism involved in symbiotic interaction|negative regulation by organism of entry into other organism during symbiotic interaction|down-regulation by organism of entry into other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052373 GO:0052372 biolink:BiologicalProcess modulation by symbiont of entry into host Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. go-plus.json regulation by organism of entry into other organism during symbiotic interaction|modulation by organism of entry into other organism during symbiotic interaction|modulation by symbiont of entry into host|regulation by organism of entry into other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052372 GO:0052371 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052371 GO:0052370 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052370 GO:0052377 biolink:BiologicalProcess obsolete evasion or tolerance by organism of symbiont-produced phytoalexins OBSOLETE. The process by which an organism avoids the effects of phytoalexins produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json evasion or tolerance by organism of symbiont-produced phytoalexins|symbiont phytoalexin detoxification|evasion or tolerance of phytoalexins produced by symbiont in response to organism|evasion or tolerance by organism of symbiont phytoalexins http://purl.obolibrary.org/obo/GO_0052377 GO:0052376 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052376 GO:0052375 biolink:BiologicalProcess obsolete evasion or tolerance by organism of symbiont-produced nitric oxide OBSOLETE. The process by which an organism avoids the effects of nitric oxide produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json evasion or tolerance by organism of symbiont-produced nitric oxide|evasion or tolerance of NO produced by symbiont in response to organism|evasion or tolerance by organism of symbiont NO|evasion or tolerance by organism of symbiont-produced NO|evasion or tolerance of nitric oxide produced by symbiont in response to organism|evasion or tolerance by organism of symbiont nitric oxide http://purl.obolibrary.org/obo/GO_0052375 CHEBI:20937 biolink:ChemicalSubstance D-fructuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20937 GO:0052374 biolink:BiologicalProcess obsolete negative regulation by symbiont of entry into host OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. go-plus.json down regulation by symbiont of entry into host|downregulation by symbiont of entry into host|down-regulation by symbiont of entry into host|inhibition by symbiont of entry into host http://purl.obolibrary.org/obo/GO_0052374 GO:0052389 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052389 UBERON:0007391 biolink:AnatomicalEntity pelvic appendage cartilage tissue A cartilage tissue that is part of a pelvic appendage. go-plus.json pelvic fin cartilage http://purl.obolibrary.org/obo/UBERON_0007391 UBERON:0007390 biolink:AnatomicalEntity pectoral appendage cartilage tissue A cartilage tissue that is part of a pectoral appendage. go-plus.json pectoral fin cartilage http://purl.obolibrary.org/obo/UBERON_0007390 GO:0052380 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052380 CHEBI:19946 biolink:ChemicalSubstance xylosylglycoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_19946 GO:0052384 biolink:BiologicalProcess obsolete evasion or tolerance by organism of symbiont-produced reactive oxygen species OBSOLETE. The process by which an organism avoids the effects of reactive oxygen species produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json evasion or tolerance of defense-related symbiont respiratory burst|evasion or tolerance of defense-related symbiont oxidative burst|evasion or tolerance by organism of symbiont-produced reactive oxygen species|evasion or tolerance of symbiont-produced AOS|evasion or tolerance of reactive oxygen species produced by symbiont in response to organism|evasion or tolerance of symbiont-produced reactive oxygen intermediates|evasion by organism of cellular damage caused by symbiont oxidative burst|evasion or tolerance of defense-related symbiont metabolic burst|evasion or tolerance of symbiont-produced ROIs|evasion or tolerance of symbiont-produced active oxygen species|evasion or tolerance of symbiont-produced ROS|evasion or tolerance by organism of reactive oxygen species produced during symbiont defense response http://purl.obolibrary.org/obo/GO_0052384 GO:0052383 biolink:BiologicalProcess obsolete induction by organism of symbiont innate immunity OBSOLETE. The activation by an organism of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of symbiont innate immune response|activation by organism of symbiont innate immunity|induction by organism of symbiont innate immune response|induction by organism of symbiont innate immunity http://purl.obolibrary.org/obo/GO_0052383 GO:0052382 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052382 GO:0052381 biolink:MolecularActivity tRNA dimethylallyltransferase activity Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine. RHEA:26482|MetaCyc:RXN0-6274|EC:2.5.1.75|Reactome:R-HSA-6787567|Reactome:R-HSA-6784462 go-plus.json tRNA isopentenyltransferase activity|tRNA prenyltransferase activity|dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity http://purl.obolibrary.org/obo/GO_0052381 GO:0052388 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052388 CHEBI:20902 biolink:ChemicalSubstance allose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_20902 GO:0052387 biolink:BiologicalProcess obsolete induction by organism of symbiont apoptosis OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of symbiont apoptosis|induction by organism of symbiont apoptotic programmed cell death|activation by organism of symbiont apoptosis|activation by organism of symbiont apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052387 GO:0052386 biolink:BiologicalProcess cell wall thickening A type of cell wall modification in which the cell wall is reinforced and made thicker. go-plus.json http://purl.obolibrary.org/obo/GO_0052386 GO:0052385 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052385 UBERON:0007389 biolink:AnatomicalEntity paired limb/fin cartilage A cartilage tissue that is part of a paired limb or fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007389 UBERON:0007386 biolink:AnatomicalEntity pelvic appendage lymph vessel A lymphatic vessel that is part of a pelvic appendage. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007386 GO:0052391 biolink:BiologicalProcess induction by symbiont of defense-related host calcium ion flux The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of host Ca2+ flux|stimulation by symbiont of defense-related host calcium ion flux|activation by organism of host calcium ion flux|up-regulation by symbiont of defense-related host calcium ion flux|positive regulation by organism of defense-related host Ca2+ flux|induction by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host calcium ion flux|induction by organism of host Ca2+ flux|up regulation by symbiont of defense-related host calcium ion flux|positive regulation by symbiont of defense-related host calcium ion flux|activation by symbiont of defense-related host calcium ion flux|positive regulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052391 UBERON:0007385 biolink:AnatomicalEntity pectoral appendage lymph vessel A lymphatic vessel that is part of a pectoral appendage. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007385 GO:0052390 biolink:BiologicalProcess induction by symbiont of host innate immune response The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json induction of host innate immunity|induction by organism of host innate immune response|positive regulation of innate immune response in other organism|positive regulation by symbiont of host innate immune response|positive regulation by symbiont of host innate immunity|up regulation by symbiont of host innate immunity|upregulation by symbiont of host innate immunity|induction by symbiont of host innate immunity|activation by organism of host innate immunity|activation by organism of host innate immune response|positive regulation of host innate immune response|induction by organism of innate immune response in other organism involved in symbiotic interaction|up-regulation by symbiont of host innate immunity|activation by symbiont of host innate immunity|stimulation by symbiont of host innate immunity http://purl.obolibrary.org/obo/GO_0052390 UBERON:0007384 biolink:AnatomicalEntity appendage lymph vessel A lymphatic vessel that is part of a limb/fin. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007384 UBERON:0007383 biolink:AnatomicalEntity enveloping layer of ectoderm Outermost layer of cells surrounding the embryo. go-plus.json enveloping layer|EVL http://purl.obolibrary.org/obo/UBERON_0007383 GO:0052395 biolink:BiologicalProcess obsolete induction by organism of defense-related symbiont nitric oxide production OBSOLETE. The activation by an organism of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of defense-related symbiont nitric oxide production|activation by organism of defense-related symbiont nitric acid production|induction by organism of defense-related symbiont NO production|activation by organism of defense-related symbiont NO production http://purl.obolibrary.org/obo/GO_0052395 GO:0052394 biolink:BiologicalProcess obsolete induction by organism of defense-related symbiont cell wall thickening OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of symbiont defense-related cell wall thickening|induction by organism of symbiont defensive cell wall thickening|induction by organism of defense-related symbiont cell wall thickening|activation by organism of symbiont defensive cell wall thickening http://purl.obolibrary.org/obo/GO_0052394 GO:0052393 biolink:BiologicalProcess obsolete induction by host of symbiont defense response OBSOLETE. The activation by an organism of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation of symbiont defense response http://purl.obolibrary.org/obo/GO_0052393 GO:0052392 biolink:BiologicalProcess obsolete induction by organism of defense-related symbiont calcium ion flux OBSOLETE. The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of symbiont calcium ion flux|activation by organism of symbiont Ca2+ flux|induction by organism of defense-related symbiont calcium ion flux|induction by organism of symbiont Ca2+ flux http://purl.obolibrary.org/obo/GO_0052392 GO:0052399 biolink:BiologicalProcess obsolete induction by organism of symbiont programmed cell death OBSOLETE. The activation by an organism of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of symbiont programmed cell death|activation by organism of symbiont programmed cell death http://purl.obolibrary.org/obo/GO_0052399 GO:0052398 biolink:BiologicalProcess obsolete induction by organism of symbiont phytoalexin production OBSOLETE. The activation by an organism of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of symbiont phytoalexin production|induction by organism of symbiont phytoalexin production http://purl.obolibrary.org/obo/GO_0052398 CHEBI:20912 biolink:ChemicalSubstance D-arabinonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_20912 GO:0052397 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052397 GO:0052396 biolink:BiologicalProcess obsolete induction by organism of symbiont non-apoptotic programmed cell death OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of symbiont non-apoptotic programmed cell death|induction by organism of symbiont non-apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052396 GO:0003315 biolink:BiologicalProcess heart rudiment formation The developmental process pertaining to the initial formation of the heart rudiment. go-plus.json heart cone formation http://purl.obolibrary.org/obo/GO_0003315 GO:0003314 biolink:BiologicalProcess heart rudiment morphogenesis The process in which the anatomical structures of the heart rudiment are generated and organized. go-plus.json heart cone morphogenesis http://purl.obolibrary.org/obo/GO_0003314 GO:0003317 biolink:BiologicalProcess cardioblast cell midline fusion The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment. go-plus.json cardiac progenitor cell midline fusion http://purl.obolibrary.org/obo/GO_0003317 GO:0003316 biolink:BiologicalProcess establishment of myocardial progenitor cell apical/basal polarity The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment. go-plus.json myocardial progenitor epithelial polarization http://purl.obolibrary.org/obo/GO_0003316 GO:0003311 biolink:BiologicalProcess pancreatic D cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin. go-plus.json pancreatic delta cell differentiation http://purl.obolibrary.org/obo/GO_0003311 GO:0003310 biolink:BiologicalProcess pancreatic A cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. go-plus.json pancreatic alpha cell differentiation http://purl.obolibrary.org/obo/GO_0003310 CHEBI:30249 biolink:ChemicalSubstance N-formyl-L-kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30249 GO:0003313 biolink:BiologicalProcess heart rudiment development The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. go-plus.json heart cone development http://purl.obolibrary.org/obo/GO_0003313 CHEBI:30248 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc go-plus.json http://purl.obolibrary.org/obo/CHEBI_30248 chebi_ph7_3 GO:0003312 biolink:BiologicalProcess pancreatic PP cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. go-plus.json pancreatic polypeptide-producing cell differentiation http://purl.obolibrary.org/obo/GO_0003312 CHEBI:44898 biolink:ChemicalSubstance pheophytin a go-plus.json http://purl.obolibrary.org/obo/CHEBI_44898 CHEBI:44897 biolink:ChemicalSubstance phosphoenolpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_44897 CHEBI:29256 biolink:ChemicalSubstance thiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29256 chebi_ph7_3 CHEBI:29259 biolink:ChemicalSubstance hydrogenphosphite go-plus.json http://purl.obolibrary.org/obo/CHEBI_29259 CHEBI:29258 biolink:ChemicalSubstance dihydrogenphosphite go-plus.json http://purl.obolibrary.org/obo/CHEBI_29258 CHEBI:136606 biolink:ChemicalSubstance N-arachidonoyl-L-phenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136606 CHEBI:29255 biolink:ChemicalSubstance hydrogenborate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29255 CHEBI:29254 biolink:ChemicalSubstance dihydrogenborate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29254 GO:0042923 biolink:MolecularActivity neuropeptide binding Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). go-plus.json http://purl.obolibrary.org/obo/GO_0042923 GO:0042922 biolink:MolecularActivity neuromedin U receptor binding Binding to one or more specific sites on a neuromedin U receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0042922 GO:0042925 biolink:MolecularActivity benzoate transmembrane transporter activity Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other. RHEA:32811 go-plus.json benzoate transporter activity http://purl.obolibrary.org/obo/GO_0042925 GO:0042924 biolink:MolecularActivity neuromedin U binding Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses. go-plus.json NMU binding http://purl.obolibrary.org/obo/GO_0042924 GO:0042921 biolink:BiologicalProcess glucocorticoid receptor signaling pathway Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor. go-plus.json glucocorticoid receptor signalling pathway http://purl.obolibrary.org/obo/GO_0042921 GO:0042920 biolink:BiologicalProcess 3-hydroxyphenylpropionic acid transmembrane transport The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other. go-plus.json m-hydroxyphenylpropionic acid transport|3-hydroxyphenylpropionic acid transport|3-(3-hydroxyphenyl)propionic acid transport http://purl.obolibrary.org/obo/GO_0042920 CHEBI:136602 biolink:ChemicalSubstance (1->4)-6-phospho-alpha-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_136602 UBERON:0007418 biolink:AnatomicalEntity neural decussation Nerve fibers crossing the midline of the neuraxis relative to their point of origin, on a course to from one level of the nervous system to another. (CUMBO, Heimer, L. The Human Brain, 2nd ed., 1995, pg 6) go-plus.json chiasm|neuraxis chiasm|decussation of neuraxis|neuraxis chiasma|chiasma|decussation|neuraxis decussation http://purl.obolibrary.org/obo/UBERON_0007418 CHEBI:30245 biolink:ChemicalSubstance linoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30245 chebi_ph7_3 UBERON:0007417 biolink:AnatomicalEntity peduncle of neuraxis go-plus.json neuraxis peduncle http://purl.obolibrary.org/obo/UBERON_0007417 GO:0042927 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042927 GO:0003319 biolink:BiologicalProcess cardioblast migration to the midline involved in heart rudiment formation The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment. go-plus.json http://purl.obolibrary.org/obo/GO_0003319 UBERON:0007415 biolink:AnatomicalEntity nucleus of midbrain reticular formation A nucleus of midbrain tegmentum that is part of a midbrain reticular formation. go-plus.json midbrain reticular nucleus|midbrain reticular formation nucleus|mesencephalic reticular nucleus http://purl.obolibrary.org/obo/UBERON_0007415 GO:0042926 biolink:MolecularActivity 3-hydroxyphenylpropionic acid transmembrane transporter activity Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other. go-plus.json 3-(3-hydroxyphenyl)propionic acid transporter activity|3-hydroxyphenylpropionic acid transporter activity|m-hydroxyphenylpropionic acid transporter activity http://purl.obolibrary.org/obo/GO_0042926 GO:0003318 biolink:BiologicalProcess cell migration to the midline involved in heart development The orderly movement of a cell toward the midline that contributes to the progression of the heart over time. go-plus.json http://purl.obolibrary.org/obo/GO_0003318 UBERON:0007414 biolink:AnatomicalEntity nucleus of midbrain tegmentum A nucleus of brain that spans a midbrain tegmentum. go-plus.json tegmental nuclei|tegmental nucleus http://purl.obolibrary.org/obo/UBERON_0007414 GO:0042929 biolink:MolecularActivity ferrichrome transmembrane transporter activity Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. go-plus.json ferrichrome transporter activity http://purl.obolibrary.org/obo/GO_0042929 GO:0042928 biolink:BiologicalProcess ferrichrome import into cell A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. go-plus.json ferrichrome transport http://purl.obolibrary.org/obo/GO_0042928 GO:0003326 biolink:BiologicalProcess pancreatic A cell fate commitment The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. go-plus.json http://purl.obolibrary.org/obo/GO_0003326 GO:0003325 biolink:BiologicalProcess pancreatic PP cell development The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0003325 GO:0003328 biolink:BiologicalProcess pancreatic D cell fate commitment The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin. go-plus.json http://purl.obolibrary.org/obo/GO_0003328 GO:0003327 biolink:BiologicalProcess type B pancreatic cell fate commitment The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. go-plus.json pancreatic B cell fate commitment http://purl.obolibrary.org/obo/GO_0003327 GO:0003322 biolink:BiologicalProcess pancreatic A cell development The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon. go-plus.json pancreatic alpha cell development http://purl.obolibrary.org/obo/GO_0003322 GO:0003321 biolink:BiologicalProcess positive regulation of blood pressure by epinephrine-norepinephrine Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine. go-plus.json http://purl.obolibrary.org/obo/GO_0003321 GO:0003324 biolink:BiologicalProcess pancreatic D cell development The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin. go-plus.json pancreatic delta cell development http://purl.obolibrary.org/obo/GO_0003324 GO:0003323 biolink:BiologicalProcess type B pancreatic cell development The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. go-plus.json pancreatic B cell development|pancreatic beta cell development http://purl.obolibrary.org/obo/GO_0003323 GO:0003320 biolink:BiologicalProcess heart rudiment involution The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube. go-plus.json http://purl.obolibrary.org/obo/GO_0003320 CHEBI:136618 biolink:ChemicalSubstance N-[(9Z)-hexadecenoyl]glycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136618 CHEBI:44884 biolink:ChemicalSubstance pentan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_44884 chebi_ph7_3 CHEBI:29269 biolink:ChemicalSubstance selenophosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29269 CHEBI:29264 biolink:ChemicalSubstance tRNA(Sec) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29264 CHEBI:29265 biolink:ChemicalSubstance Asn-tRNA(Asn) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29265 GO:0042934 biolink:MolecularActivity achromobactin transmembrane transporter activity Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other. go-plus.json achromobactin transporter activity http://purl.obolibrary.org/obo/GO_0042934 GO:0042933 biolink:MolecularActivity chrysobactin transmembrane transporter activity Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other. go-plus.json chrysobactin transporter activity http://purl.obolibrary.org/obo/GO_0042933 GO:0042936 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042936 GO:0042935 biolink:BiologicalProcess achromobactin transport The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042935 GO:0042930 biolink:BiologicalProcess enterobactin transport The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json enterochelin transport http://purl.obolibrary.org/obo/GO_0042930 CHEBI:136616 biolink:ChemicalSubstance N-oleoyl-L-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136616 CHEBI:136615 biolink:ChemicalSubstance N-oleoyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136615 CHEBI:136614 biolink:ChemicalSubstance N-oleoyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136614 GO:0042932 biolink:BiologicalProcess chrysobactin transport The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042932 GO:0042931 biolink:MolecularActivity enterobactin transmembrane transporter activity Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other. go-plus.json enterochelin transporter activity|enterobactin transporter activity http://purl.obolibrary.org/obo/GO_0042931 CHEBI:30256 biolink:ChemicalSubstance thiocarbonyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30256 chebi_ph7_3 GO:0042938 biolink:BiologicalProcess dipeptide transport The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042938 GO:0003329 biolink:BiologicalProcess pancreatic PP cell fate commitment The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0003329 GO:0042937 biolink:MolecularActivity tripeptide transmembrane transporter activity Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other. go-plus.json tripeptide transporter activity http://purl.obolibrary.org/obo/GO_0042937 GO:0042939 biolink:BiologicalProcess tripeptide transport The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042939 CHEBI:78209 biolink:ChemicalSubstance 2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78209 chebi_ph7_3 CHEBI:78208 biolink:ChemicalSubstance azelaate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78208 chebi_ph7_3 CHEBI:78207 biolink:ChemicalSubstance 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78207 chebi_ph7_3 GO:0042945 biolink:MolecularActivity D-serine transmembrane transporter activity Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid. go-plus.json D-serine transporter activity|D-serine permease activity http://purl.obolibrary.org/obo/GO_0042945 GO:0042944 biolink:MolecularActivity D-alanine transmembrane transporter activity Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid. go-plus.json D-alanine transporter activity http://purl.obolibrary.org/obo/GO_0042944 GO:0042947 biolink:MolecularActivity glucoside transmembrane transporter activity Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue. go-plus.json http://purl.obolibrary.org/obo/GO_0042947 GO:0042946 biolink:BiologicalProcess glucoside transport The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue. go-plus.json http://purl.obolibrary.org/obo/GO_0042946 GO:0042941 biolink:BiologicalProcess D-alanine transport The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042941 GO:0042940 biolink:BiologicalProcess D-amino acid transport The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042940 GO:0042943 biolink:MolecularActivity D-amino acid transmembrane transporter activity Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids. go-plus.json D-amino acid transporter activity http://purl.obolibrary.org/obo/GO_0042943 GO:0042942 biolink:BiologicalProcess D-serine transport The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042942 CHEBI:78202 biolink:ChemicalSubstance 1-alkylglycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78202 chebi_ph7_3 CHEBI:78201 biolink:ChemicalSubstance monoacylglycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78201 chebi_ph7_3 CHEBI:78200 biolink:ChemicalSubstance 2-acylglycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78200 chebi_ph7_3 CHEBI:78206 biolink:ChemicalSubstance fatty acid ethyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_78206 chebi_ph7_3 GO:0042949 biolink:BiologicalProcess arbutin transport The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042949 GO:0042948 biolink:BiologicalProcess salicin transport The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042948 CHEBI:78204 biolink:ChemicalSubstance monoalkylglycerophosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78204 chebi_ph7_3 CHEBI:78203 biolink:ChemicalSubstance 1-(alk-1-enyl)-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78203 chebi_ph7_3 GO:0003304 biolink:BiologicalProcess myocardial epithelial involution involved in heart jogging The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging. go-plus.json http://purl.obolibrary.org/obo/GO_0003304 GO:0003303 biolink:BiologicalProcess BMP signaling pathway involved in heart jogging A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging. go-plus.json BMP signalling pathway involved in heart jogging http://purl.obolibrary.org/obo/GO_0003303 CHEBI:616988 biolink:ChemicalSubstance mannose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_616988 GO:0003306 biolink:BiologicalProcess Wnt signaling pathway involved in heart development The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. go-plus.json Wnt receptor signalling pathway involved in heart development|Wnt receptor signaling pathway involved in heart development|Wnt-activated signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0003306 CHEBI:78218 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acetyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78218 chebi_ph7_3 GO:0003305 biolink:BiologicalProcess cell migration involved in heart jogging The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging. go-plus.json http://purl.obolibrary.org/obo/GO_0003305 GO:0003300 biolink:BiologicalProcess cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0003300 GO:0003302 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway involved in heart jogging A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the process of heart jogging. go-plus.json transforming growth factor beta receptor signalling pathway involved in heart jogging http://purl.obolibrary.org/obo/GO_0003302 GO:0003301 biolink:BiologicalProcess physiological cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003301 GO:0042950 biolink:MolecularActivity salicin transmembrane transporter activity Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042950 CHEBI:29242 biolink:ChemicalSubstance arsenite(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29242 chebi_ph7_3 CHEBI:29241 biolink:ChemicalSubstance silicate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29241 CHEBI:29243 biolink:ChemicalSubstance arsenite(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29243 GO:0042956 biolink:BiologicalProcess maltodextrin transport The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042956 GO:0042955 biolink:BiologicalProcess dextrin transport The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042955 GO:0042958 biolink:MolecularActivity maltodextrin transmembrane transporter activity Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042958 GO:0042957 biolink:MolecularActivity dextrin transmembrane transporter activity Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042957 GO:0042952 biolink:BiologicalProcess beta-ketoadipate pathway A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates. go-plus.json ortho-cleavage pathway http://purl.obolibrary.org/obo/GO_0042952 GO:0042951 biolink:MolecularActivity arbutin transmembrane transporter activity Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042951 GO:0042954 biolink:MolecularActivity obsolete lipoprotein transporter activity OBSOLETE. Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells. go-plus.json http://purl.obolibrary.org/obo/GO_0042954 GO:0042953 biolink:BiologicalProcess lipoprotein transport The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042953 CHEBI:78213 biolink:ChemicalSubstance 1-acylglycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78213 chebi_ph7_3 CHEBI:78211 biolink:ChemicalSubstance 1-acylglycero-3-phospho-1'-glycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78211 chebi_ph7_3 CHEBI:30232 biolink:ChemicalSubstance abieta-7,13-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_30232 chebi_ph7_3 CHEBI:78210 biolink:ChemicalSubstance monoacylglycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78210 chebi_ph7_3 GO:0003308 biolink:BiologicalProcess negative regulation of Wnt signaling pathway involved in heart development Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. go-plus.json negative regulation of Wnt receptor signalling pathway involved in heart development|negative regulation of Wnt receptor signaling pathway involved in heart development|negative regulation of Wnt-activated signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0003308 GO:0042959 biolink:MolecularActivity alkanesulfonate transmembrane transporter activity Enables the directed movement of alkanesulfonate from one side of a membrane to the other. go-plus.json alkanesulfonate transporter activity|alkanesulphonate transporter activity http://purl.obolibrary.org/obo/GO_0042959 GO:0003307 biolink:BiologicalProcess regulation of Wnt signaling pathway involved in heart development Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. go-plus.json regulation of Wnt receptor signaling pathway involved in heart development|regulation of Wnt receptor signalling pathway involved in heart development|regulation of Wnt-activated signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0003307 CHEBI:78216 biolink:ChemicalSubstance alpha,beta-didehydrotryptophan zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78216 chebi_ph7_3 CHEBI:78215 biolink:ChemicalSubstance 1-hexanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78215 chebi_ph7_3 GO:0003309 biolink:BiologicalProcess type B pancreatic cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. go-plus.json pancreatic beta cell differentiation|pancreatic B cell differentiation http://purl.obolibrary.org/obo/GO_0003309 CHEBI:78214 biolink:ChemicalSubstance 2-acylglycero-3-phospho-Lserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78214 chebi_ph7_3 CHEBI:78229 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78229 chebi_ph7_3 CHEBI:29216 biolink:ChemicalSubstance 3-hydroxy-2-methylquinolin-4(1H)-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_29216 chebi_ph7_3 CHEBI:29219 biolink:ChemicalSubstance chlorous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29219 CHEBI:29213 biolink:ChemicalSubstance sulfinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29213 GO:0042961 biolink:MolecularActivity ATPase-coupled antimonite transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out). go-plus.json ATP-dependent antimonite transporter activity|antimonite-transporting ATPase activity http://purl.obolibrary.org/obo/GO_0042961 GO:0042960 biolink:MolecularActivity antimonite secondary active transmembrane transporter activity Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json antimonite porter activity http://purl.obolibrary.org/obo/GO_0042960 CHEBI:29214 biolink:ChemicalSubstance sulfonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29214 CHEBI:29210 biolink:ChemicalSubstance trithionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29210 GO:0042967 biolink:BiologicalProcess obsolete acyl-carrier-protein biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of acyl-carrier protein. go-plus.json acyl-carrier-protein synthesis|acyl-carrier protein biosynthesis|acyl-carrier-protein formation|ACP biosynthetic process|ACP biosynthesis|acyl carrier protein biosynthesis|acyl carrier protein biosynthetic process|acyl-carrier-protein biosynthesis|acyl-carrier-protein anabolism http://purl.obolibrary.org/obo/GO_0042967 GO:0042966 biolink:BiologicalProcess biotin carboxyl carrier protein biosynthetic process The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase. go-plus.json biotin carboxyl carrier protein synthesis|biotin carboxyl carrier protein formation|BCCP biosynthesis|BCCP biosynthetic process|biotin carboxyl carrier protein biosynthesis|biotin carboxyl carrier protein anabolism http://purl.obolibrary.org/obo/GO_0042966 GO:0042969 biolink:BiologicalProcess obsolete lactone transport OBSOLETE. The directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. go-plus.json http://purl.obolibrary.org/obo/GO_0042969 GO:0042968 biolink:BiologicalProcess homoserine transport The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042968 CHEBI:78220 biolink:ChemicalSubstance 2-methyl-1-pyrrolinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_78220 chebi_ph7_3 GO:0042963 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042963 GO:0042962 biolink:MolecularActivity acridine:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out). go-plus.json acridine:hydrogen antiporter activity|acridine efflux pump activity http://purl.obolibrary.org/obo/GO_0042962 GO:0042965 biolink:BiologicalProcess obsolete glutaredoxin biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of a small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase. go-plus.json glutaredoxin anabolism|glutaredoxin synthesis|glutaredoxin formation|glutaredoxin biosynthesis http://purl.obolibrary.org/obo/GO_0042965 GO:0042964 biolink:BiologicalProcess obsolete thioredoxin reduction OBSOLETE. The chemical reactions and pathways resulting in the reduction of thioredoxin, a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. go-plus.json thioredoxin biosynthesis|thioredoxin anabolism|thioredoxin synthesis|thioredoxin formation http://purl.obolibrary.org/obo/GO_0042964 PR:000002038 biolink:Protein eotaxin-like cytokine A C/C-C motif small inducible chemokine that is a member of a subfamily that includes eotaxin. go-plus.json http://purl.obolibrary.org/obo/PR_000002038 CHEBI:78224 biolink:ChemicalSubstance 1-alkyl-2-acylglycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78224 chebi_ph7_3 CHEBI:78223 biolink:ChemicalSubstance 1-caproyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78223 chebi_ph7_3 CHEBI:78222 biolink:ChemicalSubstance (R)-2-methylpyrrolidinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_78222 chebi_ph7_3 CHEBI:30200 biolink:ChemicalSubstance kaempferol 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_30200 CHEBI:78221 biolink:ChemicalSubstance monoacylglycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78221 chebi_ph7_3 CHEBI:78228 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78228 chebi_ph7_3 CHEBI:78227 biolink:ChemicalSubstance 1,2-dicapryl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78227 chebi_ph7_3 CHEBI:78226 biolink:ChemicalSubstance 1,2-dicapryl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78226 chebi_ph7_3 CHEBI:78225 biolink:ChemicalSubstance alkyl,acylglycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78225 chebi_ph7_3 CHEBI:20891 biolink:ChemicalSubstance (R)-4'-phosphopantothenate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_20891 CHEBI:29228 biolink:ChemicalSubstance hydrogen fluoride go-plus.json http://purl.obolibrary.org/obo/CHEBI_29228 GO:0042970 biolink:MolecularActivity homoserine transmembrane transporter activity Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine. go-plus.json homoserine transporter activity http://purl.obolibrary.org/obo/GO_0042970 GO:0042972 biolink:MolecularActivity licheninase activity Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds. EC:3.2.1.73|MetaCyc:3.2.1.73-RXN go-plus.json beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity|1,3;1,4-beta-glucan 4-glucanohydrolase activity|beta-glucanase activity|1,3-1,4-beta-D-glucan 4-glucanohydrolase activity|1,3;1,4-beta-glucan endohydrolase activity|lichenase activity|1,3-1,4-beta-glucan 4-glucanohydrolase activity|endo-beta-1,3-1,4 glucanase activity|mixed linkage beta-glucanase activity http://purl.obolibrary.org/obo/GO_0042972 CHEBI:44841 biolink:ChemicalSubstance 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_44841 chebi_ph7_3 GO:0042971 biolink:MolecularActivity obsolete lactone transmembrane transporter activity OBSOLETE. Enables the transfer of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. go-plus.json http://purl.obolibrary.org/obo/GO_0042971 CHEBI:29222 biolink:ChemicalSubstance hypochlorite go-plus.json http://purl.obolibrary.org/obo/CHEBI_29222 GO:0042978 biolink:MolecularActivity ornithine decarboxylase activator activity Binds to and increases ornithine decarboxylase activity. go-plus.json L-ornithine carboxy-lyase activator activity http://purl.obolibrary.org/obo/GO_0042978 GO:0042977 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042977 GO:0042979 biolink:MolecularActivity ornithine decarboxylase regulator activity Binds to and modulates the activity of the enzyme ornithine decarboxylase. go-plus.json http://purl.obolibrary.org/obo/GO_0042979 CHEBI:78231 biolink:ChemicalSubstance 1,2-diacylglycero-3-phospho-1-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78231 chebi_ph7_3 GO:0042974 biolink:MolecularActivity retinoic acid receptor binding Binding to a retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily. go-plus.json RAR binding http://purl.obolibrary.org/obo/GO_0042974 GO:0042973 biolink:MolecularActivity glucan endo-1,3-beta-D-glucosidase activity Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans. MetaCyc:3.2.1.39-RXN|EC:3.2.1.39 go-plus.json 1,3-beta-D-glucan 3-glucanohydrolase activity|kitalase activity|oligo-1,3-glucosidase activity|beta-1,3-glucanase|callase activity|1,3-beta-D-glucan glucanohydrolase activity|endo-(1->3)-beta-D-glucanase activity|endo-1,3-beta-glucosidase activity|endo-1,3-beta-D-glucanase|laminaranase activity|endo-(1,3)-beta-D-glucanase activity|laminarinase activity|(1->3)-beta-glucan 3-glucanohydrolase activity|(1->3)-beta-glucan endohydrolase activity|endo-1,3-beta-glucanase activity http://purl.obolibrary.org/obo/GO_0042973 GO:0042976 biolink:BiologicalProcess activation of Janus kinase activity The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. go-plus.json positive regulation of JAK protein activity by tyrosine phosphorylation|tyrosine phosphorylation of JAK protein|tyrosine phosphorylation of JAK1 protein|activation of JAK2 protein|activation of JAK1 protein|activation of JAK2 kinase activity|activation of JAK1 kinase activity|tyrosine phosphorylation of JAK2 protein|activation of JAK protein|activation of JAK protein by tyrosine phosphorylation http://purl.obolibrary.org/obo/GO_0042976 GO:0042975 biolink:MolecularActivity peroxisome proliferator activated receptor binding Binding to a peroxisome proliferator activated receptor, alpha, beta or gamma. go-plus.json PPAR binding http://purl.obolibrary.org/obo/GO_0042975 CHEBI:78234 biolink:ChemicalSubstance monoacylglycero-3-phospho-1-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78234 chebi_ph7_3 CHEBI:30212 biolink:ChemicalSubstance photon go-plus.json http://purl.obolibrary.org/obo/CHEBI_30212 chebi_ph7_3 CHEBI:78233 biolink:ChemicalSubstance 2-acylglycero-3-phospho-1-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78233 chebi_ph7_3 CHEBI:78232 biolink:ChemicalSubstance 1-acylglycero-3-phospho-1-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78232 chebi_ph7_3 CHEBI:20899 biolink:ChemicalSubstance D-alloisoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_20899 CHEBI:78239 biolink:ChemicalSubstance 3-methyl-L-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78239 chebi_ph7_3 CHEBI:78237 biolink:ChemicalSubstance 3-amino-4-hydroxybenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_78237 chebi_ph7_3 CHEBI:78236 biolink:ChemicalSubstance N-acetyl-L-cysteinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78236 chebi_ph7_3 GO:0052304 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052304 GO:0052303 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052303 GO:0052302 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052302 GO:0052301 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052301 GO:0052308 biolink:BiologicalProcess obsolete pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism involved in symbiotic interaction|pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052308 GO:0052307 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052307 GO:0052306 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052306 GO:0052305 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052305 GO:0042981 biolink:BiologicalProcess regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process. go-plus.json apoptosis regulator activity|regulation of apoptosis http://purl.obolibrary.org/obo/GO_0042981 GO:0042980 biolink:MolecularActivity obsolete cystic fibrosis transmembrane conductance regulator binding OBSOLETE. Binding to a Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein. go-plus.json CFTR binding|cystic fibrosis transmembrane conductance regulator binding http://purl.obolibrary.org/obo/GO_0042980 GO:0042983 biolink:BiologicalProcess amyloid precursor protein biosynthetic process The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. go-plus.json amyloid precursor protein biosynthesis|amyloid precursor protein anabolism|amyloid precursor protein synthesis|amyloid precursor protein formation|APP biosynthesis|APP biosynthetic process http://purl.obolibrary.org/obo/GO_0042983 GO:0042982 biolink:BiologicalProcess amyloid precursor protein metabolic process The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. go-plus.json APP metabolic process|amyloid precursor protein metabolism|APP metabolism http://purl.obolibrary.org/obo/GO_0042982 GO:0052309 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052309 GO:0042989 biolink:BiologicalProcess sequestering of actin monomers The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers. go-plus.json actin monomer sequestration|sequestration of actin monomers|actin monomer sequestering|actin monomer sequestering activity|actin monomer retention|retention of actin monomers|storage of actin monomers|actin monomer storage http://purl.obolibrary.org/obo/GO_0042989 GO:0042988 biolink:MolecularActivity X11-like protein binding Binding to X11-like protein, a neuron-specific adaptor protein. go-plus.json X11L binding http://purl.obolibrary.org/obo/GO_0042988 GO:0042985 biolink:BiologicalProcess negative regulation of amyloid precursor protein biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. go-plus.json down-regulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein biosynthesis|negative regulation of amyloid precursor protein anabolism|negative regulation of amyloid precursor protein synthesis|negative regulation of amyloid precursor protein formation|downregulation of amyloid precursor protein biosynthetic process|down regulation of amyloid precursor protein biosynthetic process|inhibition of amyloid precursor protein biosynthetic process|negative regulation of APP biosynthesis|negative regulation of APP biosynthetic process http://purl.obolibrary.org/obo/GO_0042985 GO:0042984 biolink:BiologicalProcess regulation of amyloid precursor protein biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. go-plus.json regulation of amyloid precursor protein formation|regulation of APP biosynthetic process|regulation of APP biosynthesis|regulation of amyloid precursor protein biosynthesis|regulation of amyloid precursor protein anabolism|regulation of amyloid precursor protein synthesis http://purl.obolibrary.org/obo/GO_0042984 CHEBI:78241 biolink:ChemicalSubstance 5-hydroxy-3-methyl-L-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78241 chebi_ph7_3 GO:0042987 biolink:BiologicalProcess amyloid precursor protein catabolic process The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. go-plus.json APP catabolic process|APP catabolism|amyloid precursor protein degradation|amyloid precursor protein breakdown|amyloid precursor protein catabolism http://purl.obolibrary.org/obo/GO_0042987 GO:0042986 biolink:BiologicalProcess positive regulation of amyloid precursor protein biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. go-plus.json positive regulation of APP biosynthetic process|positive regulation of amyloid precursor protein anabolism|positive regulation of APP biosynthesis|positive regulation of amyloid precursor protein synthesis|positive regulation of amyloid precursor protein biosynthesis|positive regulation of amyloid precursor protein formation|up regulation of amyloid precursor protein biosynthetic process|upregulation of amyloid precursor protein biosynthetic process|stimulation of amyloid precursor protein biosynthetic process|up-regulation of amyloid precursor protein biosynthetic process|activation of amyloid precursor protein biosynthetic process http://purl.obolibrary.org/obo/GO_0042986 CHEBI:78245 biolink:ChemicalSubstance (2-amino-1-hydroxyethyl)phosphonate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78245 chebi_ph7_3 GO:0052300 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052300 CHEBI:78247 biolink:ChemicalSubstance (4S)-4-hydroxy-L-isoleucine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78247 chebi_ph7_3 GO:0052315 biolink:BiologicalProcess phytoalexin biosynthetic process The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response. go-plus.json phytoalexin biosynthesis http://purl.obolibrary.org/obo/GO_0052315 GO:0052314 biolink:BiologicalProcess phytoalexin metabolic process The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response. go-plus.json phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0052314 goslim_pir GO:0052313 biolink:BiologicalProcess modulation of nutrient release from other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of nutrient release from other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052313 GO:0052312 biolink:BiologicalProcess modulation of transcription in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction. go-plus.json modulation of transcription in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052312 GO:0052319 biolink:BiologicalProcess regulation of phytoalexin biosynthetic process Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins. go-plus.json regulation of phytoalexin biosynthesis http://purl.obolibrary.org/obo/GO_0052319 GO:0052318 biolink:BiologicalProcess regulation of phytoalexin metabolic process Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response. go-plus.json regulation of phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0052318 GO:0052317 biolink:BiologicalProcess camalexin metabolic process The chemical reactions and pathways involving camalexin, an indole phytoalexin. go-plus.json camalexin metabolism http://purl.obolibrary.org/obo/GO_0052317 GO:0052316 biolink:BiologicalProcess phytoalexin catabolic process The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response. go-plus.json phytoalexin catabolism http://purl.obolibrary.org/obo/GO_0052316 CHEBI:20873 biolink:ChemicalSubstance CDP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_20873 GO:0042992 biolink:BiologicalProcess obsolete negative regulation of transcription factor import into nucleus OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. go-plus.json down-regulation of transcription factor import into nucleus|negative regulation of transcription factor-nucleus import|downregulation of transcription factor import into nucleus|negative regulation of transcription factor import into cell nucleus|down regulation of transcription factor import into nucleus|inhibition of transcription factor import into nucleus|negative regulation of transcription factor transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0042992 CHEBI:29202 biolink:ChemicalSubstance isocyanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29202 chebi_ph7_3 GO:0042991 biolink:BiologicalProcess obsolete transcription factor import into nucleus OBSOLETE. The directed movement of a transcription factor from the cytoplasm to the nucleus. go-plus.json transcription factor-nucleus import|transcription factor import into cell nucleus|transcription factor transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0042991 GO:0042994 biolink:BiologicalProcess cytoplasmic sequestering of transcription factor The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. go-plus.json transcription factor binding, cytoplasmic sequestering|storage of transcription factor in cytoplasm|retention of transcription factor in cytoplasm|cytoplasmic retention of transcription factor|cytoplasmic storage of transcription factor|sequestering of transcription factor in cytoplasm|maintenance of transcription factor protein location in cytoplasm|cytoplasmic sequestration of transcription factor|sequestration of transcription factor in cytoplasm http://purl.obolibrary.org/obo/GO_0042994 GO:0042993 biolink:BiologicalProcess obsolete positive regulation of transcription factor import into nucleus OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. go-plus.json stimulation of transcription factor import into nucleus|activation of transcription factor import into nucleus|up-regulation of transcription factor import into nucleus|positive regulation of transcription factor-nucleus import|up regulation of transcription factor import into nucleus|positive regulation of transcription factor import into cell nucleus|upregulation of transcription factor import into nucleus|positive regulation of transcription factor transport from cytoplasm to nucleus http://purl.obolibrary.org/obo/GO_0042993 GO:0042990 biolink:BiologicalProcess obsolete regulation of transcription factor import into nucleus OBSOLETE. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. go-plus.json regulation of transcription factor transport from cytoplasm to nucleus|regulation of transcription factor-nucleus import|regulation of transcription factor import into cell nucleus http://purl.obolibrary.org/obo/GO_0042990 CHEBI:29200 biolink:ChemicalSubstance thiocyanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29200 GO:0042999 biolink:BiologicalProcess regulation of Golgi to plasma membrane CFTR protein transport Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0042999 GO:0042996 biolink:BiologicalProcess regulation of Golgi to plasma membrane protein transport Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0042996 GO:0042995 biolink:CellularComponent cell projection A prolongation or process extending from a cell, e.g. a flagellum or axon. go-plus.json cellular process|cell process|cellular projection http://purl.obolibrary.org/obo/GO_0042995 goslim_mouse|goslim_agr|goslim_pir|goslim_flybase_ribbon CHEBI:78252 biolink:ChemicalSubstance 3-hydroxy-5-methyl-1-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78252 chebi_ph7_3 GO:0042998 biolink:BiologicalProcess positive regulation of Golgi to plasma membrane protein transport Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. go-plus.json up regulation of Golgi to plasma membrane protein transport|upregulation of Golgi to plasma membrane protein transport|stimulation of Golgi to plasma membrane protein transport|up-regulation of Golgi to plasma membrane protein transport|activation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0042998 CHEBI:78251 biolink:ChemicalSubstance 5-methyl-1-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78251 chebi_ph7_3 GO:0042997 biolink:BiologicalProcess negative regulation of Golgi to plasma membrane protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. go-plus.json down-regulation of Golgi to plasma membrane protein transport|downregulation of Golgi to plasma membrane protein transport|down regulation of Golgi to plasma membrane protein transport|inhibition of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0042997 CHEBI:78257 biolink:ChemicalSubstance isogloboside go-plus.json http://purl.obolibrary.org/obo/CHEBI_78257 CHEBI:78256 biolink:ChemicalSubstance oryzalexin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_78256 chebi_ph7_3 CHEBI:78255 biolink:ChemicalSubstance 3alpha-hydroxy-ent-sandaracopimaradiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_78255 chebi_ph7_3 CHEBI:20878 biolink:ChemicalSubstance CMP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_20878 GO:0052311 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052311 GO:0052310 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052310 UBERON:0007425 biolink:AnatomicalEntity decussation of diencephalon A neural decussation that is part of a diencephalon. go-plus.json diencephalon decussation http://purl.obolibrary.org/obo/UBERON_0007425 CHEBI:78259 biolink:ChemicalSubstance oryzalexin E go-plus.json http://purl.obolibrary.org/obo/CHEBI_78259 chebi_ph7_3 CHEBI:19891 biolink:ChemicalSubstance 3,4-dihydroxyphenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_19891 GO:0003399 biolink:BiologicalProcess cytoneme morphogenesis The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003399 GO:0003398 biolink:BiologicalProcess glial cell differentiation involved in amphid sensory organ development The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ. go-plus.json http://purl.obolibrary.org/obo/GO_0003398 GO:0003395 biolink:BiologicalProcess neuron migration involved in dendrite retrograde extension The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0003395 GO:0003394 biolink:BiologicalProcess cell adhesion involved in dendrite retrograde extension The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0003394 GO:0003397 biolink:BiologicalProcess neuron migration involved in amphid sensory organ dendrite retrograde extension The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ. go-plus.json http://purl.obolibrary.org/obo/GO_0003397 GO:0003396 biolink:BiologicalProcess cell adhesion involved in amphid sensory organ dendrite retrograde extension The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ. go-plus.json http://purl.obolibrary.org/obo/GO_0003396 GO:0003391 biolink:BiologicalProcess amphid sensory organ dendrite retrograde extension The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point. go-plus.json http://purl.obolibrary.org/obo/GO_0003391 GO:0003390 biolink:BiologicalProcess dendrite development by retrograde extension The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point. go-plus.json dendrite retrograde extension http://purl.obolibrary.org/obo/GO_0003390 GO:0003393 biolink:BiologicalProcess neuron migration involved in retrograde extension The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension. go-plus.json http://purl.obolibrary.org/obo/GO_0003393 GO:0003392 biolink:BiologicalProcess cell adhesion involved in retrograde extension The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension. go-plus.json http://purl.obolibrary.org/obo/GO_0003392 CHEBI:136688 biolink:ChemicalSubstance N-acetyl-alpha-D-glucosaminyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136688 CHEBI:136687 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136687 CHEBI:136686 biolink:ChemicalSubstance (9Z,11S,12Z,15Z)-11-hydroperoxyoctadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136686 CHEBI:136683 biolink:ChemicalSubstance N-arachidonoyl-L-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136683 CHEBI:136682 biolink:ChemicalSubstance tembetarine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136682 chebi_ph7_3 NCBITaxon:629 biolink:OrganismalEntity Yersinia go-plus.json Yersinia http://purl.obolibrary.org/obo/NCBITaxon_629 CHEBI:136699 biolink:ChemicalSubstance S-adenosyl-S-carboxymethyl-L-homocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136699 CHEBI:136698 biolink:ChemicalSubstance 3-oxochenodeoxycholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136698 chebi_ph7_3 GO:0003377 biolink:BiologicalProcess obsolete regulation of apoptosis by sphingosine-1-phosphate signaling pathway OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis. go-plus.json regulation of apoptosis by sphingolipid signalling pathway|regulation of apoptosis by sphingolipid signaling pathway http://purl.obolibrary.org/obo/GO_0003377 GO:0003376 biolink:BiologicalProcess sphingosine-1-phosphate receptor signaling pathway A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json S1P-stimulated signal transduction pathway|S1P-activated G-protein coupled receptor signaling pathway|S1P-activated GPCR signaling pathway|sphingolipid signalling pathway|S1P signaling pathway|S1P receptor signaling pathway|sphingolipid signaling pathway http://purl.obolibrary.org/obo/GO_0003376 GO:0003379 biolink:BiologicalProcess establishment of cell polarity involved in gastrulation cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0003379 GO:0003378 biolink:BiologicalProcess obsolete regulation of inflammatory response by sphingosine-1-phosphate signaling pathway OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response. go-plus.json regulation of inflammatory response by sphingolipid signalling pathway|regulation of inflammatory response by sphingolipid signaling pathway http://purl.obolibrary.org/obo/GO_0003378 GO:0003373 biolink:BiologicalProcess dynamin family protein polymerization involved in membrane fission The process of creating dynamin family protein polymers, compounds composed of a large number of dynamin family protein monomers. Dynamin family protein polymers form around lipid tubes and contribute to membrane fission. go-plus.json http://purl.obolibrary.org/obo/GO_0003373 GO:0003372 biolink:BiologicalProcess establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003372 GO:0003375 biolink:BiologicalProcess regulation of dynamin family protein polymerization involved in membrane fission Any process that modulates the rate, frequency, or extent of dynamin family protein polymerization involved in mitochondrial fission. go-plus.json http://purl.obolibrary.org/obo/GO_0003375 GO:0003374 biolink:BiologicalProcess dynamin family protein polymerization involved in mitochondrial fission The process of creating dynamin protein family polymers, compounds composed of a large number of dynamin family monomers around a lipid tube of a dividing mitochondrion. Dynamin polymers form around lipid tubes and contribute to membrane fission. go-plus.json http://purl.obolibrary.org/obo/GO_0003374 GO:0003371 biolink:BiologicalProcess establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003371 NCBITaxon:632 biolink:OrganismalEntity Yersinia pestis go-plus.json Pasteurella pestis|Pestisella pestis|Bacillus pestis|Yersinia pseudotuberculosis subsp. pestis|Bacterium pestis http://purl.obolibrary.org/obo/NCBITaxon_632 GO:0003370 biolink:BiologicalProcess cell-cell adhesion involved in mesendodermal cell migration The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0003370 CHEBI:136669 biolink:ChemicalSubstance (S)-3,4-dihydroxy-2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136669 chebi_ph7_3 CHEBI:136668 biolink:ChemicalSubstance (R)-3,4-dihydroxy-2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136668 chebi_ph7_3 CHEBI:136663 biolink:ChemicalSubstance 20-hydroxyprostaglandin A1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136663 chebi_ph7_3 CHEBI:136662 biolink:ChemicalSubstance (5Z,8R,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136662 CHEBI:136661 biolink:ChemicalSubstance 20-hydroxyprostaglandin E1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136661 chebi_ph7_3 GO:0003388 biolink:BiologicalProcess neuron development involved in amphid sensory organ development The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ. go-plus.json http://purl.obolibrary.org/obo/GO_0003388 GO:0003387 biolink:BiologicalProcess neuron differentiation involved in amphid sensory organ development The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland. go-plus.json http://purl.obolibrary.org/obo/GO_0003387 GO:0003389 biolink:BiologicalProcess retrograde extension The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point. go-plus.json http://purl.obolibrary.org/obo/GO_0003389 GO:0003384 biolink:BiologicalProcess apical constriction involved in gastrulation The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0003384 GO:0003383 biolink:BiologicalProcess apical constriction The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003383 NCBITaxon:641 biolink:OrganismalEntity Vibrionaceae go-plus.json gamma-3 proteobacteria http://purl.obolibrary.org/obo/NCBITaxon_641 GO:0003386 biolink:BiologicalProcess amphid sensory organ development The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes. go-plus.json http://purl.obolibrary.org/obo/GO_0003386 GO:0003385 biolink:BiologicalProcess cell-cell signaling involved in amphid sensory organ development Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state. go-plus.json cell-cell signalling involved in amphid sensory organ development http://purl.obolibrary.org/obo/GO_0003385 GO:0003380 biolink:BiologicalProcess establishment or maintenance of cytoskeleton polarity involved in gastrulation Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0003380 GO:0003382 biolink:BiologicalProcess epithelial cell morphogenesis The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. go-plus.json http://purl.obolibrary.org/obo/GO_0003382 GO:0003381 biolink:BiologicalProcess epithelial cell morphogenesis involved in gastrulation The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0003381 CHEBI:136678 biolink:ChemicalSubstance 4',7-dihydroxyflavanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_136678 chebi_ph7_3 CHEBI:136677 biolink:ChemicalSubstance [(S)-1-acetamidoethyl]phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136677 CHEBI:136675 biolink:ChemicalSubstance (S)-(1-aminoethyl)phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136675 CHEBI:68819 biolink:ChemicalSubstance alpha-D-ribose 1,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68819 CHEBI:136679 biolink:ChemicalSubstance (R)-2-amino-4-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136679 CHEBI:136670 biolink:ChemicalSubstance (S)-2,4-dihydroxy-3-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136670 chebi_ph7_3 CHEBI:136674 biolink:ChemicalSubstance (acetamidomethyl)phosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136674 CHEBI:136673 biolink:ChemicalSubstance epitestosterone 17-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136673 chebi_ph7_3 CHEBI:136672 biolink:ChemicalSubstance N-hexadecanoyl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136672 GO:0003359 biolink:BiologicalProcess noradrenergic neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron. go-plus.json norepinephrine secreting neuron fate commitment http://purl.obolibrary.org/obo/GO_0003359 GO:0003358 biolink:BiologicalProcess noradrenergic neuron development The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. go-plus.json norepinephrine secreting neuron development http://purl.obolibrary.org/obo/GO_0003358 GO:0003355 biolink:BiologicalProcess cilium movement involved in otolith formation The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles. go-plus.json http://purl.obolibrary.org/obo/GO_0003355 GO:0003354 biolink:BiologicalProcess negative regulation of cilium movement Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. go-plus.json negative regulation of flagellum movement|negative regulation of microtubule-based flagellum movement http://purl.obolibrary.org/obo/GO_0003354 GO:0003357 biolink:BiologicalProcess noradrenergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. go-plus.json norepinephrine secreting neuron differentiation http://purl.obolibrary.org/obo/GO_0003357 GO:0003356 biolink:BiologicalProcess regulation of cilium beat frequency Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium. go-plus.json regulation of microtubule-based flagellum beat frequency|regulation of flagellum beat frequency http://purl.obolibrary.org/obo/GO_0003356 GO:0003351 biolink:BiologicalProcess epithelial cilium movement involved in extracellular fluid movement The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid. go-plus.json epithelial cilium beating|cilium movement involved in fluid flow http://purl.obolibrary.org/obo/GO_0003351 GO:0003350 biolink:BiologicalProcess pulmonary myocardium development The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein. go-plus.json http://purl.obolibrary.org/obo/GO_0003350 CHEBI:68820 biolink:ChemicalSubstance alpha-D-ribose 1-methylphosphonate 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68820 GO:0003353 biolink:BiologicalProcess positive regulation of cilium movement Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. go-plus.json positive regulation of flagellum movement|positive regulation of flagellar movement|positive regulation of microtubule-based flagellum movement http://purl.obolibrary.org/obo/GO_0003353 CHEBI:68823 biolink:ChemicalSubstance alpha-D-ribose 1-methylphosphonate 5-triphosphate(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68823 chebi_ph7_3 GO:0003352 biolink:BiologicalProcess regulation of cilium movement Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. go-plus.json regulation of microtubule-based flagellum movement|regulation of flagellum movement|regulation of flagellar movement http://purl.obolibrary.org/obo/GO_0003352 CHEBI:68822 biolink:ChemicalSubstance methylphosphonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68822 CHEBI:68829 biolink:ChemicalSubstance [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68829 CHEBI:68828 biolink:ChemicalSubstance 1-deoxy-3-dehydrosphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_68828 chebi_ph7_3 CHEBI:136642 biolink:ChemicalSubstance 17alpha-estradiol 17-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136642 chebi_ph7_3 CHEBI:136649 biolink:ChemicalSubstance estriol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136649 chebi_ph7_3 CHEBI:68825 biolink:ChemicalSubstance N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68825 CHEBI:68824 biolink:ChemicalSubstance alpha-D-ribose 1-methylphosphonate 5-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68824 CHEBI:68827 biolink:ChemicalSubstance alpha-D-GalNAc-(1->4)-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68827 CHEBI:68826 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68826 CHEBI:136641 biolink:ChemicalSubstance 17beta-estradiol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136641 chebi_ph7_3 CHEBI:136640 biolink:ChemicalSubstance (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersoninium go-plus.json http://purl.obolibrary.org/obo/CHEBI_136640 chebi_ph7_3 GO:0003369 biolink:BiologicalProcess establishment of cell polarity involved in mesendodermal cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003369 GO:0003366 biolink:BiologicalProcess cell-matrix adhesion involved in ameboidal cell migration The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003366 GO:0003365 biolink:BiologicalProcess establishment of cell polarity involved in ameboidal cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003365 GO:0003368 biolink:BiologicalProcess cell-matrix adhesion involved in mesendodermal cell migration The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003368 GO:0003367 biolink:BiologicalProcess cell-cell adhesion involved in ameboidal cell migration The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003367 GO:0003362 biolink:BiologicalProcess noradrenergic neuron fate commitment involved in brainstem development The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem. go-plus.json http://purl.obolibrary.org/obo/GO_0003362 CHEBI:68832 biolink:ChemicalSubstance 1-deoxypentalenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_68832 GO:0003361 biolink:BiologicalProcess noradrenergic neuron differentiation involved in brainstem development The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem. go-plus.json http://purl.obolibrary.org/obo/GO_0003361 CHEBI:68831 biolink:ChemicalSubstance [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68831 NCBITaxon:662 biolink:OrganismalEntity Vibrio go-plus.json Beneckea|Listonella|Microspira|Pacinia http://purl.obolibrary.org/obo/NCBITaxon_662 GO:0003364 biolink:BiologicalProcess lamellipodium assembly involved in mesendodermal cell migration Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003364 GO:0003363 biolink:BiologicalProcess lamellipodium assembly involved in ameboidal cell migration Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003363 NCBITaxon:666 biolink:OrganismalEntity Vibrio cholerae go-plus.json Kommabacillus|Pacinia cholerae-asiaticae|Vibrio comma|Liquidivibrio cholerae|Vibrio cholera|Vibrio cholerae bv. albensis|Bacillo virgola del Koch|Spirillum cholerae|Vibrio albensis|Spirillum cholerae-asiaticae|Bacillus cholerae|Microspira comma|Bacillus cholerae-asiaticae|Vibrio cholerae biovar albensis|Vibrio cholerae-asiaticae http://purl.obolibrary.org/obo/NCBITaxon_666 GO:0003360 biolink:BiologicalProcess brainstem development The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. go-plus.json http://purl.obolibrary.org/obo/GO_0003360 CHEBI:68830 biolink:ChemicalSubstance O-decanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_68830 chebi_ph7_3 CHEBI:136656 biolink:ChemicalSubstance (5Z,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136656 CHEBI:136655 biolink:ChemicalSubstance 13(R)-HODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136655 chebi_ph7_3 CHEBI:136654 biolink:ChemicalSubstance 13(S)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136654 chebi_ph7_3 CHEBI:136653 biolink:ChemicalSubstance 20-hydroxyprostaglandin E2(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136653 chebi_ph7_3 CHEBI:68836 biolink:ChemicalSubstance diphosphate group go-plus.json http://purl.obolibrary.org/obo/CHEBI_68836 CHEBI:68837 biolink:ChemicalSubstance pectate go-plus.json http://purl.obolibrary.org/obo/CHEBI_68837 chebi_ph7_3 CHEBI:136657 biolink:ChemicalSubstance (4Z,7Z,11E,13Z,16Z,19Z)-10-hydroperoxydocosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136657 CHEBI:30297 biolink:ChemicalSubstance antimonite go-plus.json http://purl.obolibrary.org/obo/CHEBI_30297 CHEBI:136650 biolink:ChemicalSubstance estriol 16-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136650 chebi_ph7_3 GO:0003337 biolink:BiologicalProcess mesenchymal to epithelial transition involved in metanephros morphogenesis A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. go-plus.json metanephric mesenchyme to epithelial transition http://purl.obolibrary.org/obo/GO_0003337 GO:0003336 biolink:BiologicalProcess corneocyte desquamation The delamination process that results in the shedding of a corneocyte from the surface of the epidermis. go-plus.json epidermal desquamation http://purl.obolibrary.org/obo/GO_0003336 GO:0003339 biolink:BiologicalProcess regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0003339 GO:0003338 biolink:BiologicalProcess metanephros morphogenesis The process in which the anatomical structures of the metanephros are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003338 GO:0003333 biolink:BiologicalProcess amino acid transmembrane transport The process in which an amino acid is transported across a membrane. go-plus.json amino acid membrane transport http://purl.obolibrary.org/obo/GO_0003333 GO:0003332 biolink:BiologicalProcess negative regulation of extracellular matrix constituent secretion Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003332 GO:0003335 biolink:BiologicalProcess corneocyte development The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0003335 GO:0003334 biolink:BiologicalProcess keratinocyte development The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0003334 CHEBI:29279 biolink:ChemicalSubstance sulfurothioic O-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29279 CHEBI:29278 biolink:ChemicalSubstance dinitride(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29278 GO:0003331 biolink:BiologicalProcess positive regulation of extracellular matrix constituent secretion Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003331 GO:0003330 biolink:BiologicalProcess regulation of extracellular matrix constituent secretion Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003330 CHEBI:29277 biolink:ChemicalSubstance dinitride(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29277 CHEBI:136623 biolink:ChemicalSubstance N-octadecanoylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136623 GO:0042901 biolink:MolecularActivity arabinan transmembrane transporter activity Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042901 CHEBI:30260 biolink:ChemicalSubstance cyromazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30260 GO:0042900 biolink:MolecularActivity arabinose transmembrane transporter activity Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042900 CHEBI:29281 biolink:ChemicalSubstance alkyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29281 CHEBI:136622 biolink:ChemicalSubstance aci-nitro compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_136622 GO:0042903 biolink:MolecularActivity tubulin deacetylase activity Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate. Reactome:R-HSA-5618331 go-plus.json http://purl.obolibrary.org/obo/GO_0042903 GO:0042902 biolink:BiologicalProcess peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan. RESID:AA0345 go-plus.json http://purl.obolibrary.org/obo/GO_0042902 CHEBI:136627 biolink:ChemicalSubstance hydroperoxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136627 CHEBI:136626 biolink:ChemicalSubstance (8R,9E,11Z,14Z)-8-hydroperoxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136626 CHEBI:136625 biolink:ChemicalSubstance 2-O-(alpha-D-mannopyranosyl)-6-O-(6-acyl-alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136625 chebi_ph7_3 CHEBI:136624 biolink:ChemicalSubstance 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136624 chebi_ph7_3 GO:0042909 biolink:BiologicalProcess acridine transport The directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042909 GO:0042908 biolink:BiologicalProcess xenobiotic transport The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json drug transport http://purl.obolibrary.org/obo/GO_0042908 goslim_pir GO:0042905 biolink:BiologicalProcess 9-cis-retinoic acid metabolic process The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative. go-plus.json 9-cis-retinoic acid metabolism http://purl.obolibrary.org/obo/GO_0042905 GO:0042904 biolink:BiologicalProcess 9-cis-retinoic acid biosynthetic process The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative. go-plus.json 9-cis-retinoic acid biosynthesis|9-cis-retinoic acid anabolism|9-cis-retinoic acid synthesis|9-cis-retinoic acid formation http://purl.obolibrary.org/obo/GO_0042904 GO:0042907 biolink:MolecularActivity xanthine transmembrane transporter activity Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids. go-plus.json http://purl.obolibrary.org/obo/GO_0042907 GO:0042906 biolink:BiologicalProcess xanthine transport The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids. go-plus.json xanthine transmembrane transport http://purl.obolibrary.org/obo/GO_0042906 GO:0003348 biolink:BiologicalProcess cardiac endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003348 GO:0003347 biolink:BiologicalProcess epicardial cell to mesenchymal cell transition A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium. go-plus.json http://purl.obolibrary.org/obo/GO_0003347 GO:0003349 biolink:BiologicalProcess epicardium-derived cardiac endothelial cell differentiation The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003349 GO:0003344 biolink:BiologicalProcess pericardium morphogenesis The process in which the anatomical structure of the pericardium is generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003344 GO:0003343 biolink:BiologicalProcess septum transversum development The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. go-plus.json http://purl.obolibrary.org/obo/GO_0003343 GO:0003346 biolink:BiologicalProcess epicardium-derived cell migration to the myocardium The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium. go-plus.json http://purl.obolibrary.org/obo/GO_0003346 GO:0003345 biolink:BiologicalProcess proepicardium cell migration involved in pericardium morphogenesis The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart. go-plus.json http://purl.obolibrary.org/obo/GO_0003345 GO:0003340 biolink:BiologicalProcess negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. go-plus.json http://purl.obolibrary.org/obo/GO_0003340 NCBITaxon:686 biolink:OrganismalEntity Vibrio cholerae O1 biovar El Tor go-plus.json Vibrio cholerae O1 biovar eltor|Vibrio eltor|Vibrio cholerae biovar El Tor|'Vibrio eltor'|Vibrio cholerae biovar eltor http://purl.obolibrary.org/obo/NCBITaxon_686 CHEBI:29289 biolink:ChemicalSubstance S-alkyl thiosulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29289 GO:0003342 biolink:BiologicalProcess proepicardium development The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. go-plus.json http://purl.obolibrary.org/obo/GO_0003342 GO:0003341 biolink:BiologicalProcess cilium movement The directed, self-propelled movement of a cilium. go-plus.json ciliary motility|flagellar motility|microtubule-based flagellum movement|flagellum movement|flagellar movement|cilium beating http://purl.obolibrary.org/obo/GO_0003341 CHEBI:136639 biolink:ChemicalSubstance testosterone 17-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136639 chebi_ph7_3 CHEBI:29287 biolink:ChemicalSubstance gold atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_29287 chebi_ph7_3 CHEBI:68851 biolink:ChemicalSubstance poly(glycerol phosphate) anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_68851 chebi_ph7_3 GO:0042912 biolink:MolecularActivity colicin transmembrane transporter activity Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1. go-plus.json http://purl.obolibrary.org/obo/GO_0042912 CHEBI:136634 biolink:ChemicalSubstance estrone 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136634 chebi_ph7_3 GO:0042911 biolink:MolecularActivity acridine transmembrane transporter activity Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene from one side of a membrane to the other. go-plus.json acridine transporter activity http://purl.obolibrary.org/obo/GO_0042911 CHEBI:136633 biolink:ChemicalSubstance (9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136633 GO:0042914 biolink:BiologicalProcess colicin transport The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1. go-plus.json http://purl.obolibrary.org/obo/GO_0042914 CHEBI:136632 biolink:ChemicalSubstance (5Z,8R,9Z,11Z,14Z)-8,9-epoxyicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136632 GO:0042913 biolink:MolecularActivity group A colicin transmembrane transporter activity Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0042913 CHEBI:136631 biolink:ChemicalSubstance (8Z,12E,14Z)-11-hydroperoxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136631 CHEBI:136638 biolink:ChemicalSubstance 9-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136638 CHEBI:136637 biolink:ChemicalSubstance steroid glucosiduronic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136637 GO:0042910 biolink:MolecularActivity xenobiotic transmembrane transporter activity Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json xenobiotic transporter activity|multidrug transporter activity|drug transmembrane transporter activity|drug transporter activity|multidrug efflux pump activity|multidrug, alkane resistant pump activity http://purl.obolibrary.org/obo/GO_0042910 goslim_metagenomics CHEBI:136636 biolink:ChemicalSubstance 16alpha-hydroxyestrone 16-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136636 chebi_ph7_3 CHEBI:136635 biolink:ChemicalSubstance 16alpha-hydroxyestrone 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136635 chebi_ph7_3 GO:0042919 biolink:BiologicalProcess benzoate transport The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042919 CHEBI:136630 biolink:ChemicalSubstance (8Z,11Z,14Z)-10-hydroperoxyicosatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136630 GO:0042916 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042916 GO:0042915 biolink:BiologicalProcess group A colicin transport The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042915 GO:0042918 biolink:BiologicalProcess alkanesulfonate transport The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical. go-plus.json alkanesulphonate transport http://purl.obolibrary.org/obo/GO_0042918 GO:0042917 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042917 UBERON:0007095 biolink:AnatomicalEntity somatic musculature go-plus.json http://purl.obolibrary.org/obo/UBERON_0007095 CHEBI:15409 biolink:ChemicalSubstance (-)-menthol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15409 chebi_ph7_3 CHEBI:15408 biolink:ChemicalSubstance (-)-isopiperitenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15408 chebi_ph7_3 GO:1904279 biolink:BiologicalProcess regulation of transcription by RNA polymerase V Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V. go-plus.json regulation of transcription from RNA pol V promoter|regulation of transcription from RNA polymerase V promoter http://purl.obolibrary.org/obo/GO_1904279 GO:1904278 biolink:BiologicalProcess positive regulation of wax biosynthetic process Any process that activates or increases the frequency, rate or extent of wax biosynthetic process. go-plus.json up regulation of wax anabolism|positive regulation of wax anabolism|activation of wax anabolism|upregulation of wax biosynthesis|upregulation of wax biosynthetic process|up regulation of wax synthesis|positive regulation of wax synthesis|activation of wax synthesis|up regulation of wax formation|positive regulation of wax formation|activation of wax formation|up-regulation of wax biosynthesis|up-regulation of wax biosynthetic process|activation of wax biosynthetic process|activation of wax biosynthesis|up-regulation of wax anabolism|up-regulation of wax synthesis|up-regulation of wax formation|upregulation of wax anabolism|positive regulation of wax biosynthesis|up regulation of wax biosynthetic process|up regulation of wax biosynthesis|upregulation of wax synthesis|upregulation of wax formation http://purl.obolibrary.org/obo/GO_1904278 GO:1904288 biolink:MolecularActivity BAT3 complex binding Binding to a BAT3 complex. go-plus.json BAG6-UBL4A-TRC35 complex binding|BAT3-TRC35-UBL4A complex binding|Bag6 complex binding http://purl.obolibrary.org/obo/GO_1904288 CHEBI:15405 biolink:ChemicalSubstance (-)-endo-fenchol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15405 chebi_ph7_3 GO:1904287 biolink:BiologicalProcess positive regulation of protein-pyridoxal-5-phosphate linkage Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage. go-plus.json stimulation of protein-pyridoxal-5-phosphate linkage|up regulation of protein-pyridoxal-5-phosphate linkage|activation of protein-pyridoxal-5-phosphate linkage|up-regulation of protein-pyridoxal-5-phosphate linkage|upregulation of protein-pyridoxal-5-phosphate linkage http://purl.obolibrary.org/obo/GO_1904287 CHEBI:15404 biolink:ChemicalSubstance (-)-homoisocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15404 chebi_ph7_3 GO:1904286 biolink:BiologicalProcess negative regulation of protein-pyridoxal-5-phosphate linkage Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage. go-plus.json down regulation of protein-pyridoxal-5-phosphate linkage|downregulation of protein-pyridoxal-5-phosphate linkage|down-regulation of protein-pyridoxal-5-phosphate linkage|inhibition of protein-pyridoxal-5-phosphate linkage http://purl.obolibrary.org/obo/GO_1904286 CHEBI:15407 biolink:ChemicalSubstance (-)-ephedrine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15407 GO:1904285 biolink:BiologicalProcess regulation of protein-pyridoxal-5-phosphate linkage Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage. go-plus.json http://purl.obolibrary.org/obo/GO_1904285 CHEBI:15406 biolink:ChemicalSubstance (-)-trans-isopiperitenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15406 chebi_ph7_3 GO:1904284 biolink:BiologicalProcess positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I. go-plus.json activation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|activation of antigen processing and presentation of endogenous peptide antigen via MHC class I|positive regulation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of endogenous peptide antigen processing and presentation via MHC class I|up-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|upregulation of endogenous peptide antigen processing and presentation via MHC class I|upregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|up-regulation of endogenous peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_1904284 UBERON:0007099 biolink:AnatomicalEntity hyoid neural crest Cranial neural crest that migrates into the hyoid arch. go-plus.json hyoid crest http://purl.obolibrary.org/obo/UBERON_0007099 CHEBI:15401 biolink:ChemicalSubstance (+)-dihydrokaempferol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15401 chebi_ph7_3 GO:1904283 biolink:BiologicalProcess negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I. go-plus.json downregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|down-regulation of endogenous peptide antigen processing and presentation via MHC class I|negative regulation of endogenous peptide antigen processing and presentation via MHC class I|down-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|downregulation of endogenous peptide antigen processing and presentation via MHC class I|inhibition of antigen processing and presentation of endogenous peptide antigen via MHC class I|down regulation of endogenous peptide antigen processing and presentation via MHC class I|inhibition of endogenous peptide antigen processing and presentation via MHC class I|down regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I http://purl.obolibrary.org/obo/GO_1904283 UBERON:0007098 biolink:AnatomicalEntity mandibular neural crest Cranial neural crest that migrates into the mandibular arch. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007098 CHEBI:15400 biolink:ChemicalSubstance (-)-carvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15400 chebi_ph7_3 GO:1904282 biolink:BiologicalProcess regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I. go-plus.json regulation of antigen presentation, endogenous peptide antigen|regulation of antigen processing, endogenous antigen via MHC class I|regulation of antigen processing, endogenous antigen via major histocompatibility complex class I|regulation of endogenous peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_1904282 CHEBI:15403 biolink:ChemicalSubstance (+)-sabinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15403 chebi_ph7_3 GO:1904281 biolink:BiologicalProcess positive regulation of transcription by RNA polymerase V Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V. go-plus.json up regulation of transcription from RNA pol V promoter|up-regulation of transcription from RNA polymerase V promoter|activation of transcription from RNA polymerase V promoter|positive regulation of transcription from RNA pol V promoter|activation of transcription from RNA pol V promoter|up-regulation of transcription from RNA pol V promoter|up regulation of transcription from RNA polymerase V promoter|upregulation of transcription from RNA pol V promoter|upregulation of transcription from RNA polymerase V promoter|positive regulation of transcription from RNA polymerase V promoter http://purl.obolibrary.org/obo/GO_1904281 CHEBI:15402 biolink:ChemicalSubstance (+)-neomenthol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15402 chebi_ph7_3 GO:1904280 biolink:BiologicalProcess negative regulation of transcription by RNA polymerase V Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V. go-plus.json down-regulation of transcription from RNA pol V promoter|negative regulation of transcription from RNA pol V promoter|down-regulation of transcription from RNA polymerase V promoter|inhibition of transcription from RNA pol V promoter|downregulation of transcription from RNA polymerase V promoter|down regulation of transcription from RNA polymerase V promoter|inhibition of transcription from RNA polymerase V promoter|negative regulation of transcription from RNA polymerase V promoter|down regulation of transcription from RNA pol V promoter|downregulation of transcription from RNA pol V promoter http://purl.obolibrary.org/obo/GO_1904280 GO:1904289 biolink:BiologicalProcess regulation of mitotic DNA damage checkpoint Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint. go-plus.json http://purl.obolibrary.org/obo/GO_1904289 GO:1904299 biolink:BiologicalProcess negative regulation of transcytosis Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis. go-plus.json down-regulation of transcytosis|downregulation of transcytosis|down regulation of transcytosis|inhibition of transcytosis http://purl.obolibrary.org/obo/GO_1904299 GO:1904298 biolink:BiologicalProcess regulation of transcytosis Any process that modulates the frequency, rate or extent of transcytosis. go-plus.json http://purl.obolibrary.org/obo/GO_1904298 GO:1904297 biolink:BiologicalProcess positive regulation of osmolarity-sensing cation channel activity Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity. go-plus.json up regulation of osmolarity-sensing cation channel activity|upregulation of osmolarity-sensing cation channel activity|activation of osmolarity-sensing cation channel activity|up-regulation of osmolarity-sensing cation channel activity http://purl.obolibrary.org/obo/GO_1904297 GO:1904296 biolink:BiologicalProcess negative regulation of osmolarity-sensing cation channel activity Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity. go-plus.json downregulation of osmolarity-sensing cation channel activity|down regulation of osmolarity-sensing cation channel activity|inhibition of osmolarity-sensing cation channel activity|down-regulation of osmolarity-sensing cation channel activity http://purl.obolibrary.org/obo/GO_1904296 GO:1904295 biolink:BiologicalProcess regulation of osmolarity-sensing cation channel activity Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904295 GO:1904294 biolink:BiologicalProcess positive regulation of ERAD pathway Any process that activates or increases the frequency, rate or extent of ERAD pathway. go-plus.json upregulation of ERAD pathway|positive regulation of endoplasmic reticulum-associated degradation|upregulation of ER-associated degradation pathway|up regulation of endoplasmic reticulum-associated degradation|upregulation of endoplasmic reticulum-associated protein degradation pathway|up-regulation of ERAD pathway|activation of ERAD pathway|up regulation of ER-associated degradation pathway|upregulation of endoplasmic reticulum-associated degradation|positive regulation of ER-associated degradation pathway|up-regulation of endoplasmic reticulum-associated protein degradation pathway|activation of ER-associated degradation pathway|up regulation of ERAD pathway|activation of endoplasmic reticulum-associated protein degradation pathway|up-regulation of endoplasmic reticulum-associated degradation|activation of endoplasmic reticulum-associated degradation|up-regulation of ER-associated degradation pathway|positive regulation of endoplasmic reticulum-associated protein degradation pathway|up regulation of endoplasmic reticulum-associated protein degradation pathway http://purl.obolibrary.org/obo/GO_1904294 GO:1904293 biolink:BiologicalProcess negative regulation of ERAD pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway. go-plus.json inhibition of ERAD pathway|negative regulation of endoplasmic reticulum-associated degradation|down-regulation of endoplasmic reticulum-associated degradation|inhibition of ER-associated degradation pathway|downregulation of endoplasmic reticulum-associated protein degradation pathway|down regulation of endoplasmic reticulum-associated protein degradation pathway|down regulation of ER-associated degradation pathway|downregulation of endoplasmic reticulum-associated degradation|downregulation of ER-associated degradation pathway|inhibition of endoplasmic reticulum-associated protein degradation pathway|down regulation of endoplasmic reticulum-associated degradation|inhibition of endoplasmic reticulum-associated degradation|down-regulation of ERAD pathway|down-regulation of ER-associated degradation pathway|negative regulation of ER-associated degradation pathway|down-regulation of endoplasmic reticulum-associated protein degradation pathway|negative regulation of endoplasmic reticulum-associated protein degradation pathway|downregulation of ERAD pathway|down regulation of ERAD pathway http://purl.obolibrary.org/obo/GO_1904293 GO:1904292 biolink:BiologicalProcess regulation of ERAD pathway Any process that modulates the frequency, rate or extent of ERAD pathway. go-plus.json regulation of endoplasmic reticulum-associated protein degradation pathway|regulation of ER-associated degradation pathway|regulation of endoplasmic reticulum-associated degradation http://purl.obolibrary.org/obo/GO_1904292 GO:1904291 biolink:BiologicalProcess positive regulation of mitotic DNA damage checkpoint Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint. go-plus.json up-regulation of mitotic DNA damage checkpoint|upregulation of mitotic DNA damage checkpoint|up regulation of mitotic DNA damage checkpoint|activation of mitotic DNA damage checkpoint http://purl.obolibrary.org/obo/GO_1904291 GO:1904290 biolink:BiologicalProcess negative regulation of mitotic DNA damage checkpoint Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint. go-plus.json inhibition of mitotic DNA damage checkpoint|down regulation of mitotic DNA damage checkpoint|downregulation of mitotic DNA damage checkpoint|down-regulation of mitotic DNA damage checkpoint http://purl.obolibrary.org/obo/GO_1904290 CHEBI:15427 biolink:ChemicalSubstance N(2)-(2-carboxyethyl)-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15427 CHEBI:15426 biolink:ChemicalSubstance deoxyamidinoproclavaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15426 CHEBI:15429 biolink:ChemicalSubstance hydroxylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15429 chebi_ph7_3 CHEBI:15428 biolink:ChemicalSubstance glycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15428 CHEBI:15423 biolink:ChemicalSubstance clavaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15423 CHEBI:15422 biolink:ChemicalSubstance ATP go-plus.json http://purl.obolibrary.org/obo/CHEBI_15422 CHEBI:15425 biolink:ChemicalSubstance proclavaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15425 CHEBI:15424 biolink:ChemicalSubstance dihydroclavaminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15424 CHEBI:15421 biolink:ChemicalSubstance perillyl aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15421 chebi_ph7_3 CHEBI:15420 biolink:ChemicalSubstance perillyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15420 chebi_ph7_3 CHEBI:15419 biolink:ChemicalSubstance ent-7alpha-hydroxykaur-16-en-19-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15419 CHEBI:15416 biolink:ChemicalSubstance ent-kaur-16-en-19-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15416 chebi_ph7_3 CHEBI:15415 biolink:ChemicalSubstance ent-kaurene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15415 chebi_ph7_3 CHEBI:15418 biolink:ChemicalSubstance ent-kaur-16-en-19-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_15418 chebi_ph7_3 CHEBI:15417 biolink:ChemicalSubstance ent-kaur-16-en-19-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15417 CHEBI:15412 biolink:ChemicalSubstance (-)-ureidoglycolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15412 CHEBI:15411 biolink:ChemicalSubstance (-)-menthyl beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_15411 chebi_ph7_3 CHEBI:15414 biolink:ChemicalSubstance S-adenosyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15414 CHEBI:15413 biolink:ChemicalSubstance 2',4,4',6'-tetrahydroxychalcone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15413 CHEBI:15410 biolink:ChemicalSubstance (-)-menthone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15410 chebi_ph7_3 CHEBI:8871 biolink:ChemicalSubstance risperidone go-plus.json http://purl.obolibrary.org/obo/CHEBI_8871 CHEBI:64405 biolink:ChemicalSubstance F-9775A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64405 chebi_ph7_3 CHEBI:64409 biolink:ChemicalSubstance F-9775B go-plus.json http://purl.obolibrary.org/obo/CHEBI_64409 chebi_ph7_3 CHEBI:64406 biolink:ChemicalSubstance EC 3.4.22.38 (cathepsin K) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64406 CHEBI:64411 biolink:ChemicalSubstance EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64411 CHEBI:64410 biolink:ChemicalSubstance gerfelin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64410 CHEBI:64416 biolink:ChemicalSubstance EC 1.3.1.43 (arogenate dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64416 CHEBI:64415 biolink:ChemicalSubstance violaceol I go-plus.json http://purl.obolibrary.org/obo/CHEBI_64415 CHEBI:64413 biolink:ChemicalSubstance diorcinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64413 chebi_ph7_3 CHEBI:64419 biolink:ChemicalSubstance meroterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64419 CHEBI:64418 biolink:ChemicalSubstance austinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64418 chebi_ph7_3 CHEBI:64417 biolink:ChemicalSubstance violaceol II go-plus.json http://purl.obolibrary.org/obo/CHEBI_64417 GO:0052447 biolink:BiologicalProcess obsolete modulation by organism of symbiont ethylene-mediated defense response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont ethylene-mediated defense response http://purl.obolibrary.org/obo/GO_0052447 GO:0052446 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont cell wall thickening OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont defensive cell wall thickening|modulation by organism of defense-related symbiont cell wall thickening http://purl.obolibrary.org/obo/GO_0052446 GO:0052445 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052445 CHEBI:15490 biolink:ChemicalSubstance 3-oxoadipyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15490 GO:0052444 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation of defense-related symbiont SA-mediated signal transduction pathway by organism|modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052444 GO:0052449 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052449 GO:0052448 biolink:BiologicalProcess obsolete modulation by organism of ethylene levels in symbiont OBSOLETE. The alteration by an organism of the levels of ethylene in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of ethylene levels in symbiont http://purl.obolibrary.org/obo/GO_0052448 PR:000002198 biolink:Protein catenin beta-1 A protein that is a translation product of the human CTNNB1 gene or a 1:1 ortholog thereof. go-plus.json CTNNB|beta-catenin|Catnb|CTNNB1 http://purl.obolibrary.org/obo/PR_000002198 GO:1904200 biolink:BiologicalProcess iodide transmembrane transport The process in which iodide is transported across a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1904200 CHEBI:39457 biolink:ChemicalSubstance pyrimidine ribonucleoside 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_39457 CHEBI:15489 biolink:ChemicalSubstance 3-oxo-fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15489 CHEBI:15488 biolink:ChemicalSubstance trans-3-methylglutaconyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15488 UBERON:0007010 biolink:AnatomicalEntity cleaving embryo Organism at the cleavage stage. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007010 CHEBI:15485 biolink:ChemicalSubstance 3-hydroxypimeloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15485 CHEBI:15484 biolink:ChemicalSubstance 3-hydroxybenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15484 CHEBI:39450 biolink:ChemicalSubstance trans-undec-2-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39450 CHEBI:15487 biolink:ChemicalSubstance isovaleryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15487 CHEBI:15486 biolink:ChemicalSubstance 3-methylbut-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15486 GO:0052443 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052443 CHEBI:39456 biolink:ChemicalSubstance antiglaucoma drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_39456 CHEBI:15481 biolink:ChemicalSubstance 3-hydroxy-2-methylpropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15481 GO:0052442 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|modulation of defense-related symbiont JA-mediated signal transduction pathway by organism http://purl.obolibrary.org/obo/GO_0052442 CHEBI:15480 biolink:ChemicalSubstance 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15480 GO:0052441 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052441 CHEBI:15483 biolink:ChemicalSubstance 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15483 GO:0052440 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052440 GO:0052458 biolink:BiologicalProcess obsolete modulation by organism of symbiont non-apoptotic programmed cell death OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont non-apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052458 GO:0052457 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont nitric oxide production OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont nitric oxide production|modulation by organism of defense-related symbiont NO production http://purl.obolibrary.org/obo/GO_0052457 GO:0052456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052456 GO:0052455 biolink:BiologicalProcess obsolete modulation by organism of jasmonic acid levels in symbiont OBSOLETE. The alteration by an organism of the levels of jasmonic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of jasmonic acid levels in symbiont http://purl.obolibrary.org/obo/GO_0052455 GO:0052459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052459 GO:1904209 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904209 GO:1904208 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904208 GO:1904207 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904207 GO:1904206 biolink:BiologicalProcess positive regulation of skeletal muscle hypertrophy Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. go-plus.json upregulation of skeletal muscle hypertrophy|up regulation of skeletal muscle hypertrophy|activation of skeletal muscle hypertrophy|up-regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_1904206 GO:1904205 biolink:BiologicalProcess negative regulation of skeletal muscle hypertrophy Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. go-plus.json down regulation of skeletal muscle hypertrophy|downregulation of skeletal muscle hypertrophy|down-regulation of skeletal muscle hypertrophy|inhibition of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_1904205 GO:1904204 biolink:BiologicalProcess regulation of skeletal muscle hypertrophy Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. go-plus.json http://purl.obolibrary.org/obo/GO_1904204 GO:1904203 biolink:BiologicalProcess positive regulation of iodide transport Any process that activates or increases the frequency, rate or extent of iodide transport. go-plus.json upregulation of iodide transport|up-regulation of iodide transport|activation of iodide transport|up regulation of iodide transport http://purl.obolibrary.org/obo/GO_1904203 GO:1904202 biolink:BiologicalProcess negative regulation of iodide transport Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport. go-plus.json downregulation of iodide transport|down regulation of iodide transport|inhibition of iodide transport|down-regulation of iodide transport http://purl.obolibrary.org/obo/GO_1904202 GO:1904201 biolink:BiologicalProcess regulation of iodide transport Any process that modulates the frequency, rate or extent of iodide transport. go-plus.json http://purl.obolibrary.org/obo/GO_1904201 GO:1904211 biolink:BiologicalProcess membrane protein proteolysis involved in retrograde protein transport, ER to cytosol Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol. go-plus.json membrane protein proteolysis involved in retrograde protein transport, endoplasmic reticulum to cytosol|membrane protein proteolysis involved in protein retrotranslocation, ER to cytosol|intramembrane cleavage of ERAD substrate|intramembrane proteolysis involved in ERAD|membrane protein proteolysis involved in protein dislocation from ER http://purl.obolibrary.org/obo/GO_1904211 GO:1904210 biolink:BiologicalProcess VCP-NPL4-UFD1 AAA ATPase complex assembly The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex. go-plus.json Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|VCP-NPL4-UFD1 AAA ATPase complex formation|p97-Ufd1-Npl4 complex assembly|p97-Ufd1-Npl4 complex formation http://purl.obolibrary.org/obo/GO_1904210 CHEBI:15478 biolink:ChemicalSubstance 2-methylcrotonoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15478 CHEBI:15477 biolink:ChemicalSubstance 2-methylbutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15477 CHEBI:15479 biolink:ChemicalSubstance isobutyryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15479 GO:0052450 biolink:BiologicalProcess obsolete modulation by organism of induced systemic resistance in symbiont OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of induced systemic resistance in symbiont http://purl.obolibrary.org/obo/GO_0052450 CHEBI:15474 biolink:ChemicalSubstance 2-furoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15474 CHEBI:15473 biolink:ChemicalSubstance crotonoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15473 CHEBI:15476 biolink:ChemicalSubstance 2-methylacetoacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15476 CHEBI:15475 biolink:ChemicalSubstance 2-hydroxyphytanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15475 GO:0052454 biolink:BiologicalProcess obsolete modulation by organism of symbiont jasmonic acid-mediated defense response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont jasmonic acid-mediated defense response|modulation by organism of symbiont JA-mediated defense response http://purl.obolibrary.org/obo/GO_0052454 CHEBI:15470 biolink:ChemicalSubstance 2,4-dichlorobenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15470 GO:0052453 biolink:BiologicalProcess obsolete modulation by organism of symbiont intracellular transport OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation of symbiont intracellular trafficking|modulation by organism of symbiont intracellular transport http://purl.obolibrary.org/obo/GO_0052453 GO:0052452 biolink:BiologicalProcess obsolete modulation by organism of symbiont innate immunity OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont innate immunity|modulation of symbiont innate immune response http://purl.obolibrary.org/obo/GO_0052452 CHEBI:15472 biolink:ChemicalSubstance anthraniloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15472 GO:0052451 biolink:BiologicalProcess obsolete modulation by organism of symbiont inflammatory response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont inflammatory response http://purl.obolibrary.org/obo/GO_0052451 CHEBI:15471 biolink:ChemicalSubstance trans-dodec-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15471 UBERON:0007005 biolink:AnatomicalEntity cardiogenic splanchnic mesoderm The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. go-plus.json cardiogenic region|cardiogenic mesoderm|cardiogenic splanchnopleure|heart primordia|cardiac mesoderm http://purl.obolibrary.org/obo/UBERON_0007005 GO:0052469 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052469 GO:0052468 biolink:BiologicalProcess obsolete modulation by organism of salicylic acid levels in symbiont OBSOLETE. The alteration by an organism of the levels of salicylic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of salicylic acid levels in symbiont http://purl.obolibrary.org/obo/GO_0052468 GO:0052467 biolink:BiologicalProcess obsolete modulation by organism of symbiont salicylic acid-mediated defense response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont salicylic acid-mediated defense response|modulation by organism of symbiont SA-mediated defense response http://purl.obolibrary.org/obo/GO_0052467 GO:0052466 biolink:BiologicalProcess obsolete modulation by organism of symbiont resistance gene-dependent defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense response in symbiont by specific elicitors|modulation by organism of symbiont gene-for-gene resistance|modulation by organism of symbiont resistance gene-dependent defense response|modulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont http://purl.obolibrary.org/obo/GO_0052466 GO:1904219 biolink:BiologicalProcess positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity. go-plus.json upregulation of phosphatidylserine synthase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|up regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of phosphatidylserine synthetase activity|up regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|activation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of PS synthase activity|upregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|up regulation of CDP-diglyceride:serine phosphatidyltransferase activity|positive regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|positive regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|activation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up regulation of phosphatidylserine synthetase activity|positive regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of PS synthase activity|activation of CDP-diglyceride:serine phosphatidyltransferase activity|up-regulation of phosphatidylserine synthase activity|activation of phosphatidylserine synthase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|upregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|up-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|activation of CDPdiglyceride-serine O-phosphatidyltransferase activity|upregulation of phosphatidylserine synthetase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of PS synthase activity|up-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|positive regulation of phosphatidylserine synthase activity|up regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up regulation of phosphatidylserine synthase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|activation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|positive regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of phosphatidylserine synthetase activity|up regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|positive regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|activation of phosphatidylserine synthetase activity|upregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up-regulation of PS synthase activity|activation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|activation of PS synthase activity|upregulation of CDP-diglyceride:serine phosphatidyltransferase activity|positive regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity http://purl.obolibrary.org/obo/GO_1904219 GO:1904218 biolink:BiologicalProcess negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity. go-plus.json down-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|negative regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|downregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|inhibition of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of phosphatidylserine synthetase activity|negative regulation of phosphatidylserine synthetase activity|downregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|negative regulation of PS synthase activity|down-regulation of PS synthase activity|down regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|downregulation of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|inhibition of CDPdiglyceride-serine O-phosphatidyltransferase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|inhibition of CDP-diglyceride-L-serine phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|negative regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|downregulation of phosphatidylserine synthetase activity|downregulation of PS synthase activity|down-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|down regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|down regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down regulation of phosphatidylserine synthetase activity|inhibition of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|down regulation of PS synthase activity|inhibition of phosphatidylserine synthetase activity|down-regulation of phosphatidylserine synthase activity|inhibition of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|inhibition of PS synthase activity|negative regulation of phosphatidylserine synthase activity|inhibition of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|downregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|inhibition of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|negative regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|downregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|downregulation of phosphatidylserine synthase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|down-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|negative regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down regulation of phosphatidylserine synthase activity|inhibition of phosphatidylserine synthase activity|down regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity http://purl.obolibrary.org/obo/GO_1904218 GO:1904217 biolink:BiologicalProcess regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity. go-plus.json regulation of CDP-diglyceride:serine phosphatidyltransferase activity|regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|regulation of phosphatidylserine synthetase activity|regulation of PS synthase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|regulation of serine exchange enzyme|regulation of phosphatidylserine synthase activity|regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity http://purl.obolibrary.org/obo/GO_1904217 GO:1904216 biolink:BiologicalProcess positive regulation of protein import into chloroplast stroma Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma. go-plus.json up regulation of chloroplast stroma protein import|up-regulation of protein import into chloroplast stroma|activation of protein import into chloroplast stroma|activation of chloroplast stroma protein import|up-regulation of protein transport into chloroplast stroma|positive regulation of chloroplast stroma protein import|upregulation of protein transport into chloroplast stroma|up-regulation of chloroplast stroma protein import|up regulation of protein import into chloroplast stroma|up regulation of protein transport into chloroplast stroma|activation of protein transport into chloroplast stroma|upregulation of chloroplast stroma protein import|positive regulation of protein transport into chloroplast stroma|upregulation of protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_1904216 GO:1904215 biolink:BiologicalProcess regulation of protein import into chloroplast stroma Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma. go-plus.json regulation of protein transport into chloroplast stroma|regulation of chloroplast stroma protein import http://purl.obolibrary.org/obo/GO_1904215 GO:1904214 biolink:BiologicalProcess positive regulation of iodide transmembrane transport Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport. go-plus.json activation of iodide transmembrane transport|up-regulation of iodide transmembrane transport|up regulation of iodide transmembrane transport|upregulation of iodide transmembrane transport http://purl.obolibrary.org/obo/GO_1904214 GO:1904213 biolink:BiologicalProcess negative regulation of iodide transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport. go-plus.json down-regulation of iodide transmembrane transport|downregulation of iodide transmembrane transport|down regulation of iodide transmembrane transport|inhibition of iodide transmembrane transport http://purl.obolibrary.org/obo/GO_1904213 GO:1904212 biolink:BiologicalProcess regulation of iodide transmembrane transport Any process that modulates the frequency, rate or extent of iodide transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1904212 GO:1904222 biolink:BiologicalProcess positive regulation of serine C-palmitoyltransferase activity Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity. go-plus.json activation of serine C-palmitoyltransferase activity|upregulation of 3-oxosphinganine synthetase activity|upregulation of SPT|up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up-regulation of 3-oxosphinganine synthetase activity|activation of 3-oxosphinganine synthetase activity|up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up regulation of SPT|up regulation of serine C-palmitoyltransferase activity|positive regulation of SPT|activation of acyl-CoA:serine C-2 acyltransferase decarboxylating|activation of SPT|up-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|positive regulation of 3-oxosphinganine synthetase activity|upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|upregulation of serine C-palmitoyltransferase activity|up regulation of 3-oxosphinganine synthetase activity|up-regulation of SPT|upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up-regulation of serine C-palmitoyltransferase activity|activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity http://purl.obolibrary.org/obo/GO_1904222 GO:1904221 biolink:BiologicalProcess negative regulation of serine C-palmitoyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity. go-plus.json downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down regulation of SPT|down-regulation of serine C-palmitoyltransferase activity|downregulation of SPT|negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|downregulation of serine C-palmitoyltransferase activity|down-regulation of 3-oxosphinganine synthetase activity|negative regulation of 3-oxosphinganine synthetase activity|down-regulation of SPT|down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|negative regulation of SPT|down regulation of serine C-palmitoyltransferase activity|inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|inhibition of serine C-palmitoyltransferase activity|inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating|downregulation of 3-oxosphinganine synthetase activity|down regulation of 3-oxosphinganine synthetase activity|inhibition of SPT|down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|inhibition of 3-oxosphinganine synthetase activity http://purl.obolibrary.org/obo/GO_1904221 CHEBI:39437 biolink:ChemicalSubstance tocol go-plus.json http://purl.obolibrary.org/obo/CHEBI_39437 GO:1904220 biolink:BiologicalProcess regulation of serine C-palmitoyltransferase activity Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity. go-plus.json regulation of serine palmitoyltransferase|regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|regulation of SPT|regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|regulation of 3-oxosphinganine synthetase activity http://purl.obolibrary.org/obo/GO_1904220 CHEBI:39436 biolink:ChemicalSubstance chromenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_39436 CHEBI:39435 biolink:ChemicalSubstance cycloheptafuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_39435 CHEBI:39439 biolink:ChemicalSubstance benzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_39439 GO:0052461 biolink:BiologicalProcess obsolete modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. go-plus.json modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity http://purl.obolibrary.org/obo/GO_0052461 GO:0052460 biolink:BiologicalProcess modulation by host of nutrient release from symbiont Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052460 GO:0052465 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont reactive oxygen species production OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont metabolic burst|modulation by organism of defense-related symbiont active oxygen species production|modulation by organism of defense-related symbiont ROS production|modulation by organism of defense-related symbiont respiratory burst|modulation by organism of defense-related symbiont reactive oxygen intermediate production|modulation by organism of defense-related symbiont reactive oxygen species production|modulation by organism of defense-related symbiont reactive oxidative species production|modulation by organism of defense-related symbiont AOS production|modulation by organism of defense-related symbiont oxidative burst|modulation by organism of defense-related symbiont ROI production http://purl.obolibrary.org/obo/GO_0052465 CHEBI:39434 biolink:ChemicalSubstance limonoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39434 GO:0052464 biolink:BiologicalProcess obsolete modulation by organism of symbiont programmed cell death OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation of symbiont PCD|modulation by organism of symbiont programmed cell death|modulation of symbiont HR|modulation of symbiont hypersensitive response http://purl.obolibrary.org/obo/GO_0052464 GO:0052463 biolink:BiologicalProcess obsolete modulation by organism of symbiont phytoalexin production OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont phytoalexin production http://purl.obolibrary.org/obo/GO_0052463 CHEBI:39432 biolink:ChemicalSubstance furochromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_39432 GO:0052462 biolink:BiologicalProcess obsolete modulation by host of symbiont phagocytosis OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052462 GO:0052479 biolink:BiologicalProcess obsolete negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|suppression by organism of defense-related symbiont ethylene-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052479 GO:0052478 biolink:BiologicalProcess obsolete negative regulation by organism of defense-related symbiont cell wall callose deposition OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of defense-related symbiont cell wall callose deposition http://purl.obolibrary.org/obo/GO_0052478 GO:0052477 biolink:BiologicalProcess obsolete negative regulation by organism of defense-related symbiont callose deposition OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of callose deposition performed by the symbiont as part of its defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json suppression by organism of defense-related symbiont callose deposition|negative regulation by organism of defense-related symbiont callose deposition http://purl.obolibrary.org/obo/GO_0052477 PR:000002190 biolink:Protein RAC-alpha serine/threonine-protein kinase An AKT kinase that is a translation product of the human AKT1 gene or a 1:1 ortholog thereof. go-plus.json AKT1|Akt|RAC-PK-alpha|proto-oncogene c-Akt|protein kinase B|thymoma viral proto-oncogene|AKT1 kinase|PKB|RAC http://purl.obolibrary.org/obo/PR_000002190 GO:1904229 biolink:BiologicalProcess regulation of succinate dehydrogenase activity Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity. go-plus.json regulation of succinate:acceptor oxidoreductase activity|regulation of fumarate dehydrogenase activity|regulation of fumaric hydrogenase activity|regulation of succinic dehydrogenase activity|regulation of fumarate reductase activity|regulation of succinate:(acceptor) oxidoreductase activity|regulation of succinate oxidoreductase activity|regulation of succinic acid dehydrogenase activity|regulation of succinodehydrogenase activity|regulation of succinyl dehydrogenase activity http://purl.obolibrary.org/obo/GO_1904229 GO:1904228 biolink:BiologicalProcess positive regulation of glycogen synthase activity, transferring glucose-1-phosphate Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate. go-plus.json upregulation of glycogen synthase activity, transferring glucose-1-phosphate|activation of glycogen synthase activity, transferring glucose-1-phosphate|up-regulation of glycogen synthase activity, transferring glucose-1-phosphate|up regulation of glycogen synthase activity, transferring glucose-1-phosphate http://purl.obolibrary.org/obo/GO_1904228 GO:1904227 biolink:BiologicalProcess negative regulation of glycogen synthase activity, transferring glucose-1-phosphate Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate. go-plus.json down-regulation of glycogen synthase activity, transferring glucose-1-phosphate|downregulation of glycogen synthase activity, transferring glucose-1-phosphate|down regulation of glycogen synthase activity, transferring glucose-1-phosphate|inhibition of glycogen synthase activity, transferring glucose-1-phosphate http://purl.obolibrary.org/obo/GO_1904227 GO:1904226 biolink:BiologicalProcess regulation of glycogen synthase activity, transferring glucose-1-phosphate Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_1904226 GO:1904225 biolink:BiologicalProcess positive regulation of glucuronosyltransferase activity Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity. go-plus.json up regulation of p-nitrophenylglucuronosyltransferase activity|upregulation of UDP-glucuronosyltransferase activity|up regulation of p-phenylphenol glucuronyltransferase activity|up-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of ciramadol UDP-glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of UDPGA transferase activity|up-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|activation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of UDP glucuronosyltransferase activity|up regulation of bilirubin glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of UDPGT activity|up-regulation of pnp-UDPGT activity|positive regulation of p-nitrophenylglucuronosyltransferase activity|positive regulation of p-phenylphenol glucuronyltransferase activity|upregulation of 1-naphthol-UDP-glucuronosyltransferase activity|positive regulation of 4-nitrophenol UDPGT activity|activation of UDPGT activity|up-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of glucuronosyltransferase activity|positive regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|activation of bilirubin UDPGT activity|up regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of 17-OH steroid UDPGT activity|up regulation of UDP glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|upregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|upregulation of bilirubin monoglucuronide glucuronyltransferase activity|up regulation of UDPGA transferase activity|upregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of bilirubin UDP-glucuronosyltransferase activity|activation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|positive regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|upregulation of UDP-glucuronyltransferase activity|positive regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 4-nitrophenol UDPGT activity|up-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of 17-OH steroid UDPGT activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of p-nitrophenol UDP-glucuronyltransferase activity|activation of 3-OH androgenic UDPGT activity|up-regulation of uridine diphosphoglucuronyltransferase activity|positive regulation of UDP glucuronyltransferase activity|up-regulation of uridine 5'-diphosphoglucuronyltransferase activity|activation of ciramadol UDP-glucuronyltransferase activity|up regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|positive regulation of p-nitrophenol UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of bilirubin UDPGT activity|activation of uridine 5'-diphosphoglucuronyltransferase activity|activation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up regulation of UDP glucuronyltransferase activity|activation of UDP glucuronate-estriol glucuronosyltransferase activity|up regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of UDPGA-glucuronyltransferase activity|upregulation of PNP-UDPGT|upregulation of UDP glucuronic acid transferase activity|activation of p-nitrophenylglucuronosyltransferase activity|activation of pnp-UDPGT activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of p-phenylphenol glucuronyltransferase activity|upregulation of estrone UDPglucuronosyltransferase activity|up regulation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of UDPGA-glucuronyltransferase activity|up regulation of phenyl-UDP-glucuronosyltransferase activity|upregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of estriol UDPglucuronosyltransferase activity|positive regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of UDP-glucuronosyltransferase activity|up regulation of morphine glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|up regulation of bilirubin UDPGT activity|upregulation of bilirubin uridine diphosphoglucuronyltransferase activity|activation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|activation of 4-nitrophenol UDP-glucuronyltransferase activity|up regulation of 1-naphthol glucuronyltransferase activity|activation of UDP-glucuronosyltransferase activity|positive regulation of 3-OH androgenic UDPGT activity|positive regulation of phenyl-UDP-glucuronosyltransferase activity|activation of bilirubin UDP-glucuronosyltransferase activity|activation of p-hydroxybiphenyl UDP glucuronyltransferase activity|upregulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of GT activity|positive regulation of ciramadol UDP-glucuronyltransferase activity|upregulation of bilirubin glucuronyltransferase activity|upregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of 1-naphthol glucuronyltransferase activity|positive regulation of morphine glucuronyltransferase activity|up regulation of 1-naphthol-UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of UDP glucuronate-estriol glucuronosyltransferase activity|upregulation of glucuronosyltransferase activity|up regulation of 3-OH androgenic UDPGT activity|positive regulation of UDPGT activity|up regulation of p-nitrophenol UDP-glucuronyltransferase activity|activation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of bilirubin monoglucuronide glucuronyltransferase activity|positive regulation of pnp-UDPGT activity|up-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|positive regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|upregulation of UDPGA transferase activity|up-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of ciramadol UDP-glucuronyltransferase activity|up-regulation of p-nitrophenylglucuronosyltransferase activity|up-regulation of UDP-glucuronyltransferase activity|up-regulation of p-phenylphenol glucuronyltransferase activity|upregulation of UDP glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|up-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|positive regulation of 1-naphthol-UDP-glucuronosyltransferase activity|up regulation of UDP glucuronate-estriol glucuronosyltransferase activity|up regulation of UDPGT activity|up regulation of pnp-UDPGT activity|upregulation of 4-nitrophenol UDPGT activity|positive regulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of UDP-glucuronyltransferase activity|upregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of bilirubin UDP-glucuronosyltransferase activity|upregulation of 17-OH steroid UDPGT activity|up-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|activation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up-regulation of UDP glucuronic acid transferase activity|activation of morphine glucuronyltransferase activity|upregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up regulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of 1-naphthol glucuronyltransferase activity|positive regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of uridine diphosphate glucuronyltransferase activity|up regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of UDP glucuronic acid transferase activity|up regulation of PNP-UDPGT|up regulation of bilirubin UDP-glucuronosyltransferase activity|positive regulation of uridine 5'-diphosphoglucuronyltransferase activity|upregulation of UDP glucuronyltransferase activity|up regulation of estriol UDPglucuronosyltransferase activity|positive regulation of UDPGA-glucuronyltransferase activity|upregulation of p-nitrophenol UDP-glucuronosyltransferase activity|activation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of bilirubin monoglucuronide glucuronyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of estrone UDPglucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of PNP-UDPGT|up regulation of uridine 5'-diphosphoglucuronyltransferase activity|up regulation of bilirubin uridine diphosphoglucuronyltransferase activity|activation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of GT activity|up regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of bilirubin UDPGT activity|activation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of UDP-glucuronosyltransferase activity|up regulation of UDPGA-glucuronyltransferase activity|positive regulation of estrone UDPglucuronosyltransferase activity|up-regulation of bilirubin glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of estriol UDPglucuronosyltransferase activity|upregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of glucuronosyltransferase activity|up-regulation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up regulation of UDP-glucuronosyltransferase activity|up-regulation of UDPGA transferase activity|activation of uridine diphosphoglucuronosyltransferase activity|up-regulation of morphine glucuronyltransferase activity|upregulation of p-nitrophenol UDP-glucuronyltransferase activity|upregulation of 3-OH androgenic UDPGT activity|positive regulation of uridine diphosphoglucuronosyltransferase activity|upregulation of p-nitrophenylglucuronosyltransferase activity|up-regulation of UDP glucuronosyltransferase activity|up-regulation of 1-naphthol glucuronyltransferase activity|activation of glucuronosyltransferase activity|upregulation of p-phenylphenol glucuronyltransferase activity|activation of UDP glucuronosyltransferase activity|up-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|upregulation of ciramadol UDP-glucuronyltransferase activity|positive regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of bilirubin monoglucuronide glucuronyltransferase activity|up-regulation of 4-nitrophenol UDPGT activity|activation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of UDPGA transferase activity|upregulation of UDPGT activity|up-regulation of 17-OH steroid UDPGT activity|upregulation of UDP glucuronate-estriol glucuronosyltransferase activity|upregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronyltransferase activity|upregulation of pnp-UDPGT activity|positive regulation of UDP-glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of PNP-UDPGT|positive regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|activation of estrone UDPglucuronosyltransferase activity|up regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of estriol UDPglucuronosyltransferase activity|up regulation of bilirubin monoglucuronide glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronyltransferase activity|activation of bilirubin uridine diphosphoglucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of UDP-glucuronyltransferase activity|up regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of uridine diphosphoglucuronyltransferase activity|up-regulation of UDP glucuronyltransferase activity|activation of bilirubin glucuronyltransferase activity|up regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up-regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|activation of UDP glucuronyltransferase activity|upregulation of bilirubin UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of UDP glucuronic acid transferase activity|activation of uridine diphosphate glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of bilirubin UDPGT activity|up regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|activation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of 4-nitrophenol UDPGT activity|activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|upregulation of uridine 5'-diphosphoglucuronyltransferase activity|up regulation of UDP glucuronic acid transferase activity|upregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of GT activity|up regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|upregulation of phenyl-UDP-glucuronosyltransferase activity|upregulation of UDPGA-glucuronyltransferase activity|activation of 17-OH steroid UDPGT activity|positive regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|up-regulation of PNP-UDPGT|up-regulation of 3-OH androgenic UDPGT activity|upregulation of morphine glucuronyltransferase activity|up-regulation of estrone UDPglucuronosyltransferase activity|upregulation of 1-naphthol glucuronyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronyltransferase activity|positive regulation of GT activity|up regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of estriol UDPglucuronosyltransferase activity|activation of GT activity|positive regulation of bilirubin glucuronyltransferase activity http://purl.obolibrary.org/obo/GO_1904225 GO:1904224 biolink:BiologicalProcess negative regulation of glucuronosyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity. go-plus.json down regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down regulation of phenyl-UDP-glucuronosyltransferase activity|negative regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|downregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|downregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronosyltransferase activity|down-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|downregulation of UDP glucuronic acid transferase activity|inhibition of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of 1-naphthol glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|negative regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down-regulation of uridine diphosphate glucuronyltransferase activity|down-regulation of UDP glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of morphine glucuronyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDP-glucuronyltransferase activity|negative regulation of UDP glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|negative regulation of uridine diphosphate glucuronyltransferase activity|negative regulation of bilirubin UDPGT activity|inhibition of UDP-glucuronyltransferase activity|down-regulation of bilirubin UDPGT activity|inhibition of estriol UDPglucuronosyltransferase activity|inhibition of PNP-UDPGT|downregulation of bilirubin glucuronyltransferase activity|inhibition of estrone UDPglucuronosyltransferase activity|down-regulation of GT activity|down regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|negative regulation of GT activity|down-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|negative regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of phenyl-UDP-glucuronosyltransferase activity|down regulation of 1-naphthol-UDP-glucuronosyltransferase activity|down-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|inhibition of uridine diphosphoglucuronyltransferase activity|inhibition of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of UDP glucuronic acid transferase activity|negative regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|down regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of glucuronosyltransferase activity|down-regulation of p-phenylphenol glucuronyltransferase activity|down-regulation of 3-OH androgenic UDPGT activity|inhibition of UDP glucuronic acid transferase activity|downregulation of 1-naphthol glucuronyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronyltransferase activity|negative regulation of p-nitrophenylglucuronosyltransferase activity|negative regulation of 3-OH androgenic UDPGT activity|negative regulation of p-phenylphenol glucuronyltransferase activity|negative regulation of p-nitrophenol UDP-glucuronyltransferase activity|downregulation of morphine glucuronyltransferase activity|down-regulation of p-nitrophenylglucuronosyltransferase activity|downregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of 4-nitrophenol UDPGT activity|downregulation of UDP glucuronosyltransferase activity|negative regulation of ciramadol UDP-glucuronyltransferase activity|inhibition of bilirubin monoglucuronide glucuronyltransferase activity|inhibition of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|downregulation of UDPGA transferase activity|down-regulation of ciramadol UDP-glucuronyltransferase activity|inhibition of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of UDP glucuronate-estriol glucuronosyltransferase activity|negative regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of pnp-UDPGT activity|down-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|inhibition of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of pnp-UDPGT activity|down-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|inhibition of 4-methylumbelliferone UDP-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of 17-OH steroid UDPGT activity|down regulation of bilirubin glucuronyltransferase activity|down-regulation of UDPGT activity|negative regulation of UDPGT activity|downregulation of 1-naphthol-UDP-glucuronosyltransferase activity|down regulation of glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of GT activity|negative regulation of 4-nitrophenol UDP-glucuronyltransferase activity|downregulation of uridine diphosphate glucuronyltransferase activity|downregulation of UDP glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|negative regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of PNP-UDPGT|down-regulation of bilirubin UDP-glucuronosyltransferase activity|down regulation of estrone UDPglucuronosyltransferase activity|downregulation of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDPGA transferase activity|down regulation of UDP glucuronosyltransferase activity|negative regulation of bilirubin UDP-glucuronosyltransferase activity|inhibition of glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down regulation of estriol UDPglucuronosyltransferase activity|down regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down regulation of 4-nitrophenol UDPGT activity|inhibition of UDPGA transferase activity|down regulation of bilirubin uridine diphosphoglucuronyltransferase activity|inhibition of UDP glucuronosyltransferase activity|downregulation of bilirubin UDPGT activity|inhibition of UDP glucuronate-estradiol-glucuronosyltransferase activity|down regulation of 17-OH steroid UDPGT activity|inhibition of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of uridine 5'-diphosphoglucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down regulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of phenyl-UDP-glucuronosyltransferase activity|down-regulation of uridine 5'-diphosphoglucuronyltransferase activity|downregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|down-regulation of phenyl-UDP-glucuronosyltransferase activity|down regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|down regulation of uridine diphosphate glucuronyltransferase activity|down-regulation of UDPGA-glucuronyltransferase activity|inhibition of bilirubin glucuronyltransferase activity|down-regulation of morphine glucuronyltransferase activity|downregulation of 3-OH androgenic UDPGT activity|downregulation of p-nitrophenol UDP-glucuronyltransferase activity|downregulation of estrone UDPglucuronosyltransferase activity|down regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down-regulation of 1-naphthol glucuronyltransferase activity|downregulation of PNP-UDPGT|negative regulation of morphine glucuronyltransferase activity|negative regulation of UDPGA-glucuronyltransferase activity|inhibition of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|downregulation of estriol UDPglucuronosyltransferase activity|down regulation of UDP glucuronyltransferase activity|negative regulation of 1-naphthol glucuronyltransferase activity|downregulation of ciramadol UDP-glucuronyltransferase activity|inhibition of UDP glucuronyltransferase activity|downregulation of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of bilirubin UDPGT activity|inhibition of uridine diphosphate glucuronyltransferase activity|downregulation of pnp-UDPGT activity|inhibition of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|negative regulation of UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|down-regulation of UDP-glucuronosyltransferase activity|downregulation of UDP glucuronate-estriol glucuronosyltransferase activity|inhibition of p-nitrophenylglucuronosyltransferase activity|downregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of p-phenylphenol glucuronyltransferase activity|inhibition of 4-nitrophenol UDPGT activity|inhibition of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of UDPGT activity|down-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronosyltransferase activity|down regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|down regulation of uridine diphosphoglucuronyltransferase activity|negative regulation of 1-naphthol-UDP-glucuronosyltransferase activity|down regulation of 3-OH androgenic UDPGT activity|negative regulation of bilirubin monoglucuronide glucuronyltransferase activity|downregulation of 4-nitrophenol UDP-glucuronyltransferase activity|negative regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of p-nitrophenol UDP-glucuronyltransferase activity|down-regulation of bilirubin monoglucuronide glucuronyltransferase activity|down-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|inhibition of 17-OH steroid UDPGT activity|inhibition of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of ciramadol UDP-glucuronyltransferase activity|negative regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|negative regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|downregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of bilirubin UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|down-regulation of UDP-glucuronyltransferase activity|negative regulation of UDP-glucuronyltransferase activity|downregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down regulation of pnp-UDPGT activity|down regulation of UDP glucuronate-estriol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronyltransferase activity|downregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDPGT activity|downregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|inhibition of bilirubin UDPGT activity|downregulation of uridine 5'-diphosphoglucuronyltransferase activity|down regulation of 4-nitrophenol UDP-glucuronyltransferase activity|down regulation of GT activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|inhibition of UDPGT activity|down-regulation of PNP-UDPGT|down-regulation of estrone UDPglucuronosyltransferase activity|down regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of bilirubin UDP-glucuronosyltransferase activity|negative regulation of PNP-UDPGT|down-regulation of UDP glucuronic acid transferase activity|negative regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|negative regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|down-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of estriol UDPglucuronosyltransferase activity|down-regulation of estriol UDPglucuronosyltransferase activity|downregulation of UDPGA-glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|negative regulation of UDP glucuronic acid transferase activity|negative regulation of estrone UDPglucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of p-nitrophenylglucuronosyltransferase activity|negative regulation of bilirubin uridine diphosphoglucuronyltransferase activity|inhibition of UDP-glucuronate-bilirubin glucuronyltransferase activity|down regulation of p-phenylphenol glucuronyltransferase activity|down-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|inhibition of p-nitrophenol UDP-glucuronyltransferase activity|down regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of phenyl-UDP-glucuronosyltransferase activity|downregulation of UDP-glucuronosyltransferase activity|inhibition of 3-OH androgenic UDPGT activity|downregulation of GT activity|negative regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of 1-naphthol glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronosyltransferase activity|down regulation of uridine 5'-diphosphoglucuronyltransferase activity|down-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of morphine glucuronyltransferase activity|down-regulation of bilirubin glucuronyltransferase activity|inhibition of ciramadol UDP-glucuronyltransferase activity|negative regulation of bilirubin glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of bilirubin monoglucuronide glucuronyltransferase activity|inhibition of uridine 5'-diphosphoglucuronyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|inhibition of UDP glucuronate-estriol glucuronosyltransferase activity|downregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of UDPGA-glucuronyltransferase activity|inhibition of pnp-UDPGT activity|inhibition of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|downregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|downregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|inhibition of UDPGA-glucuronyltransferase activity|downregulation of p-nitrophenylglucuronosyltransferase activity|downregulation of p-phenylphenol glucuronyltransferase activity|down-regulation of glucuronosyltransferase activity|down-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down-regulation of UDPGA transferase activity|inhibition of 4-nitrophenol UDP-glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|negative regulation of UDP glucuronosyltransferase activity|inhibition of 1-naphthol-UDP-glucuronosyltransferase activity|negative regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of 4-nitrophenol UDPGT activity|down-regulation of UDP glucuronosyltransferase activity|negative regulation of 4-nitrophenol UDPGT activity|negative regulation of UDPGA transferase activity|down regulation of UDP-glucuronosyltransferase activity|downregulation of UDP-glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronyltransferase activity|downregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of 17-OH steroid UDPGT activity|negative regulation of uridine diphosphoglucuronyltransferase activity|inhibition of UDP-glucuronosyltransferase activity|negative regulation of 17-OH steroid UDPGT activity|inhibition of bilirubin UDP-glucuronosyltransferase activity|inhibition of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of bilirubin monoglucuronide glucuronyltransferase activity http://purl.obolibrary.org/obo/GO_1904224 GO:1904223 biolink:BiologicalProcess regulation of glucuronosyltransferase activity Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity. go-plus.json regulation of UDP glucuronic acid transferase activity|regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|regulation of phenyl-UDP-glucuronosyltransferase activity|regulation of 1-naphthol glucuronyltransferase activity|regulation of morphine glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|regulation of bilirubin glucuronyltransferase activity|regulation of 1-naphthol-UDP-glucuronosyltransferase activity|regulation of UDPGA transferase activity|regulation of UDP glucuronosyltransferase activity|regulation of 4-nitrophenol UDPGT activity|regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|regulation of 17-OH steroid UDPGT activity|regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|regulation of PNP-UDPGT|regulation of UDP glucuronyltransferase activity|regulation of uridine diphosphate glucuronyltransferase activity|regulation of estrone UDPglucuronosyltransferase activity|regulation of p-nitrophenol UDP-glucuronosyltransferase activity|regulation of estriol UDPglucuronosyltransferase activity|regulation of bilirubin UDPGT activity|regulation of bilirubin uridine diphosphoglucuronyltransferase activity|regulation of uridine diphosphoglucuronosyltransferase activity|regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of 3-OH androgenic UDPGT activity|regulation of p-nitrophenol UDP-glucuronyltransferase activity|regulation of ciramadol UDP-glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of UDPGT activity|regulation of UDP glucuronate-estriol glucuronosyltransferase activity|regulation of uridine diphosphoglucuronyltransferase activity|regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|regulation of pnp-UDPGT activity|regulation of 4-nitrophenol UDP-glucuronyltransferase activity|regulation of bilirubin UDP-glucuronosyltransferase activity|regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|regulation of GT activity|regulation of uridine 5'-diphosphoglucuronyltransferase activity|regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDPGA-glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|regulation of UDP-glucuronosyltransferase activity|regulation of p-phenylphenol glucuronyltransferase activity|regulation of p-nitrophenylglucuronosyltransferase activity|regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of bilirubin monoglucuronide glucuronyltransferase activity|regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|regulation of UDP-glucuronyltransferase activity|regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_1904223 GO:1904233 biolink:BiologicalProcess negative regulation of aconitate hydratase activity Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity. go-plus.json downregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down regulation of citrate(isocitrate) hydro-lyase activity|inhibition of citrate(isocitrate) hydro-lyase activity|down-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|negative regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of cis-aconitase activity|down-regulation of aconitate hydratase activity|negative regulation of aconitase activity|negative regulation of cis-aconitase activity|down-regulation of aconitase activity|inhibition of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of citrate(isocitrate) hydro-lyase activity|negative regulation of citrate(isocitrate) hydro-lyase activity|downregulation of aconitate hydratase activity|downregulation of aconitase activity|downregulation of cis-aconitase activity|down regulation of cis-aconitase activity|down regulation of aconitase activity|down regulation of aconitate hydratase activity|down regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|inhibition of aconitase activity|inhibition of aconitate hydratase activity|inhibition of cis-aconitase activity|downregulation of citrate(isocitrate) hydro-lyase activity http://purl.obolibrary.org/obo/GO_1904233 CHEBI:39449 biolink:ChemicalSubstance 2-undecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39449 CHEBI:39448 biolink:ChemicalSubstance undecenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39448 GO:1904232 biolink:BiologicalProcess regulation of aconitate hydratase activity Any process that modulates the frequency, rate or extent of aconitate hydratase activity. go-plus.json regulation of citrate(isocitrate) hydro-lyase activity|regulation of citrate hydro-lyase activity|regulation of cis-aconitase activity|regulation of aconitase activity|regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming) http://purl.obolibrary.org/obo/GO_1904232 GO:1904231 biolink:BiologicalProcess positive regulation of succinate dehydrogenase activity Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity. go-plus.json positive regulation of fumarate reductase activity|positive regulation of succinate:acceptor oxidoreductase activity|up regulation of succinate oxidoreductase activity|upregulation of succinic acid dehydrogenase activity|upregulation of succinate:(acceptor) oxidoreductase activity|activation of succinate oxidoreductase activity|up regulation of succinate:acceptor oxidoreductase activity|positive regulation of succinate oxidoreductase activity|positive regulation of fumaric hydrogenase activity|up regulation of succinodehydrogenase activity|upregulation of fumarate dehydrogenase activity|activation of succinodehydrogenase activity|up regulation of succinyl dehydrogenase activity|up regulation of fumaric hydrogenase activity|positive regulation of succinodehydrogenase activity|up regulation of succinate dehydrogenase activity|activation of succinyl dehydrogenase activity|up-regulation of fumarate reductase activity|positive regulation of succinyl dehydrogenase activity|activation of succinate:(acceptor) oxidoreductase activity|up-regulation of succinic acid dehydrogenase activity|up-regulation of succinate:(acceptor) oxidoreductase activity|activation of succinic acid dehydrogenase activity|upregulation of succinate:acceptor oxidoreductase activity|up-regulation of succinate oxidoreductase activity|up regulation of fumarate dehydrogenase activity|activation of fumarate dehydrogenase activity|upregulation of fumaric hydrogenase activity|up-regulation of succinodehydrogenase activity|upregulation of succinate dehydrogenase activity|upregulation of fumarate reductase activity|positive regulation of fumarate dehydrogenase activity|up-regulation of succinyl dehydrogenase activity|positive regulation of succinate:(acceptor) oxidoreductase activity|up-regulation of succinate:acceptor oxidoreductase activity|positive regulation of succinic acid dehydrogenase activity|activation of succinate:acceptor oxidoreductase activity|up regulation of succinate:(acceptor) oxidoreductase activity|up regulation of succinic acid dehydrogenase activity|upregulation of succinate oxidoreductase activity|up-regulation of fumaric hydrogenase activity|activation of fumaric hydrogenase activity|activation of succinate dehydrogenase activity|upregulation of succinodehydrogenase activity|up-regulation of succinate dehydrogenase activity|up regulation of fumarate reductase activity|up-regulation of fumarate dehydrogenase activity|activation of fumarate reductase activity|upregulation of succinyl dehydrogenase activity http://purl.obolibrary.org/obo/GO_1904231 CHEBI:39447 biolink:ChemicalSubstance pyrimidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_39447 GO:1904230 biolink:BiologicalProcess negative regulation of succinate dehydrogenase activity Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity. go-plus.json down regulation of succinic acid dehydrogenase activity|down regulation of succinyl dehydrogenase activity|down regulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinate oxidoreductase activity|negative regulation of fumaric hydrogenase activity|down-regulation of fumaric hydrogenase activity|downregulation of succinodehydrogenase activity|down-regulation of succinate dehydrogenase activity|negative regulation of fumarate reductase activity|inhibition of succinic acid dehydrogenase activity|inhibition of succinate:(acceptor) oxidoreductase activity|down-regulation of fumarate reductase activity|downregulation of succinyl dehydrogenase activity|downregulation of succinate:acceptor oxidoreductase activity|inhibition of fumarate reductase activity|negative regulation of succinate oxidoreductase activity|down regulation of fumarate dehydrogenase activity|down-regulation of succinate oxidoreductase activity|downregulation of fumaric hydrogenase activity|down-regulation of succinodehydrogenase activity|downregulation of succinate dehydrogenase activity|negative regulation of succinodehydrogenase activity|down regulation of succinate:acceptor oxidoreductase activity|down-regulation of succinyl dehydrogenase activity|inhibition of succinate:acceptor oxidoreductase activity|negative regulation of succinyl dehydrogenase activity|downregulation of fumarate dehydrogenase activity|down regulation of fumaric hydrogenase activity|down regulation of succinate dehydrogenase activity|inhibition of succinate oxidoreductase activity|inhibition of fumaric hydrogenase activity|inhibition of succinate dehydrogenase activity|inhibition of succinodehydrogenase activity|down-regulation of succinic acid dehydrogenase activity|down-regulation of succinate:(acceptor) oxidoreductase activity|negative regulation of succinic acid dehydrogenase activity|negative regulation of succinate:(acceptor) oxidoreductase activity|inhibition of succinyl dehydrogenase activity|down regulation of fumarate reductase activity|down-regulation of fumarate dehydrogenase activity|negative regulation of fumarate dehydrogenase activity|downregulation of fumarate reductase activity|downregulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinic acid dehydrogenase activity|down regulation of succinate oxidoreductase activity|inhibition of fumarate dehydrogenase activity|negative regulation of succinate:acceptor oxidoreductase activity|down regulation of succinodehydrogenase activity|down-regulation of succinate:acceptor oxidoreductase activity http://purl.obolibrary.org/obo/GO_1904230 CHEBI:39446 biolink:ChemicalSubstance pyrimidine ribonucleosides go-plus.json http://purl.obolibrary.org/obo/CHEBI_39446 CHEBI:15499 biolink:ChemicalSubstance 4-coumaroyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15499 GO:0052472 biolink:BiologicalProcess modulation by host of symbiont transcription Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0052472 CHEBI:15496 biolink:ChemicalSubstance 4-aminobutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15496 GO:0052471 biolink:BiologicalProcess obsolete modulation by organism of systemic acquired resistance in symbiont OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of systemic acquired resistance in symbiont http://purl.obolibrary.org/obo/GO_0052471 CHEBI:15495 biolink:ChemicalSubstance 4,8,12-trimethyltridecanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15495 GO:0052470 biolink:BiologicalProcess obsolete modulation by host of symbiont signal transduction pathway OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052470 CHEBI:15498 biolink:ChemicalSubstance 4-chlorobenzoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15498 CHEBI:15497 biolink:ChemicalSubstance trans-4-carboxybut-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15497 GO:0052476 biolink:BiologicalProcess obsolete negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|suppression by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052476 CHEBI:15492 biolink:ChemicalSubstance 3-oxopimeloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15492 GO:0052475 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont cell-mediated immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of symbiont cell-based immune response|negative regulation by organism of symbiont cell-mediated immune response http://purl.obolibrary.org/obo/GO_0052475 CHEBI:15491 biolink:ChemicalSubstance 3-oxopalmitoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15491 GO:0052474 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont T-cell mediated immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of symbiont T-cell mediated immune response http://purl.obolibrary.org/obo/GO_0052474 CHEBI:15494 biolink:ChemicalSubstance 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15494 GO:0052473 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont B-cell mediated immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of symbiont B-cell mediated immune response http://purl.obolibrary.org/obo/GO_0052473 CHEBI:39442 biolink:ChemicalSubstance fluorescent probe go-plus.json http://purl.obolibrary.org/obo/CHEBI_39442 CHEBI:15493 biolink:ChemicalSubstance 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15493 GO:0052489 biolink:BiologicalProcess negative regulation by host of symbiont programmed cell death Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json inhibition of symbiont programmed cell death|downregulation by host of symbiont programmed cell death|down regulation by host of symbiont programmed cell death|inhibition by host of symbiont programmed cell death|down-regulation by host of symbiont programmed cell death http://purl.obolibrary.org/obo/GO_0052489 GO:0052488 biolink:BiologicalProcess obsolete negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. go-plus.json suppression of general elicitor induced symbiont innate immunity|suppression of PAMP-induced symbiont innate immunity|suppression of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of MAMP-induced symbiont innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of PAMP induced symbiont innate immunity|suppression of MAMP induced symbiont innate immunity|suppression of general elicitor-induced symbiont innate immunity http://purl.obolibrary.org/obo/GO_0052488 GO:1904239 biolink:BiologicalProcess regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly. go-plus.json regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|regulation of p97-Ufd1-Npl4 complex assembly|regulation of p97-Ufd1-Npl4 complex formation|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation http://purl.obolibrary.org/obo/GO_1904239 CHEBI:40410 biolink:ChemicalSubstance N-acetylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_40410 GO:1904238 biolink:BiologicalProcess pericyte cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell. go-plus.json http://purl.obolibrary.org/obo/GO_1904238 GO:1904237 biolink:BiologicalProcess positive regulation of substrate-dependent cell migration, cell attachment to substrate Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate. go-plus.json up-regulation of substrate-bound cell migration, cell attachment to substrate|up-regulation of substrate-dependent cell migration, cell attachment to substrate|activation of substrate-bound cell migration, cell attachment to substrate|activation of substrate-dependent cell migration, cell attachment to substrate|positive regulation of substrate-bound cell migration, cell attachment to substrate|up regulation of substrate-bound cell migration, cell attachment to substrate|up regulation of substrate-dependent cell migration, cell attachment to substrate|upregulation of substrate-bound cell migration, cell attachment to substrate|upregulation of substrate-dependent cell migration, cell attachment to substrate http://purl.obolibrary.org/obo/GO_1904237 GO:1904236 biolink:BiologicalProcess negative regulation of substrate-dependent cell migration, cell attachment to substrate Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate. go-plus.json down-regulation of substrate-bound cell migration, cell attachment to substrate|negative regulation of substrate-bound cell migration, cell attachment to substrate|down-regulation of substrate-dependent cell migration, cell attachment to substrate|downregulation of substrate-bound cell migration, cell attachment to substrate|downregulation of substrate-dependent cell migration, cell attachment to substrate|down regulation of substrate-bound cell migration, cell attachment to substrate|inhibition of substrate-bound cell migration, cell attachment to substrate|down regulation of substrate-dependent cell migration, cell attachment to substrate|inhibition of substrate-dependent cell migration, cell attachment to substrate http://purl.obolibrary.org/obo/GO_1904236 GO:1904235 biolink:BiologicalProcess regulation of substrate-dependent cell migration, cell attachment to substrate Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate. go-plus.json regulation of substrate-bound cell migration, cell attachment to substrate http://purl.obolibrary.org/obo/GO_1904235 GO:1904234 biolink:BiologicalProcess positive regulation of aconitate hydratase activity Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity. go-plus.json up regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|activation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|upregulation of citrate(isocitrate) hydro-lyase activity|up-regulation of cis-aconitase activity|up-regulation of aconitase activity|up-regulation of aconitate hydratase activity|activation of cis-aconitase activity|activation of aconitase activity|activation of aconitate hydratase activity|up-regulation of citrate(isocitrate) hydro-lyase activity|up-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|activation of citrate(isocitrate) hydro-lyase activity|positive regulation of aconitase activity|positive regulation of cis-aconitase activity|up regulation of cis-aconitase activity|up regulation of aconitate hydratase activity|up regulation of aconitase activity|upregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of citrate(isocitrate) hydro-lyase activity|up regulation of citrate(isocitrate) hydro-lyase activity|upregulation of cis-aconitase activity|upregulation of aconitate hydratase activity|upregulation of aconitase activity http://purl.obolibrary.org/obo/GO_1904234 GO:1904244 biolink:BiologicalProcess positive regulation of pancreatic trypsinogen secretion Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion. go-plus.json upregulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen secretion|up-regulation of pancreatic trypsinogen release|activation of pancreatic trypsinogen release|upregulation of pancreatic trypsinogen secretion|positive regulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen release|up-regulation of pancreatic trypsinogen secretion|activation of pancreatic trypsinogen secretion http://purl.obolibrary.org/obo/GO_1904244 CHEBI:15449 biolink:ChemicalSubstance (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15449 CHEBI:15448 biolink:ChemicalSubstance (1-hydroxycyclohexyl)acetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15448 GO:1904243 biolink:BiologicalProcess negative regulation of pancreatic trypsinogen secretion Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion. go-plus.json down regulation of pancreatic trypsinogen release|inhibition of pancreatic trypsinogen release|down-regulation of pancreatic trypsinogen secretion|downregulation of pancreatic trypsinogen secretion|down regulation of pancreatic trypsinogen secretion|inhibition of pancreatic trypsinogen secretion|down-regulation of pancreatic trypsinogen release|negative regulation of pancreatic trypsinogen release|downregulation of pancreatic trypsinogen release http://purl.obolibrary.org/obo/GO_1904243 GO:1904242 biolink:BiologicalProcess regulation of pancreatic trypsinogen secretion Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion. go-plus.json regulation of pancreatic trypsinogen release http://purl.obolibrary.org/obo/GO_1904242 GO:1904241 biolink:BiologicalProcess positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly. go-plus.json activation of p97-Ufd1-Npl4 complex formation|activation of p97-Ufd1-Npl4 complex assembly|up-regulation of p97-Ufd1-Npl4 complex assembly|positive regulation of p97-Ufd1-Npl4 complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|activation of VCP-NPL4-UFD1 AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|positive regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up-regulation of p97-Ufd1-Npl4 complex formation|positive regulation of p97-Ufd1-Npl4 complex assembly|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex assembly|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of p97-Ufd1-Npl4 complex formation|upregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|upregulation of p97-Ufd1-Npl4 complex assembly|upregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|activation of VCP-NPL4-UFD1 AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex formation http://purl.obolibrary.org/obo/GO_1904241 GO:1904240 biolink:BiologicalProcess negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly. go-plus.json down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of p97-Ufd1-Npl4 complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|negative regulation of p97-Ufd1-Npl4 complex formation|negative regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down-regulation of p97-Ufd1-Npl4 complex assembly|negative regulation of p97-Ufd1-Npl4 complex assembly|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|inhibition of p97-Ufd1-Npl4 complex formation|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|downregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|inhibition of VCP-NPL4-UFD1 AAA ATPase complex assembly|downregulation of p97-Ufd1-Npl4 complex assembly|down regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|inhibition of VCP-NPL4-UFD1 AAA ATPase complex formation|down regulation of p97-Ufd1-Npl4 complex assembly|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|inhibition of p97-Ufd1-Npl4 complex assembly|down regulation of p97-Ufd1-Npl4 complex formation|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|downregulation of p97-Ufd1-Npl4 complex formation|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|downregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation http://purl.obolibrary.org/obo/GO_1904240 CHEBI:15444 biolink:ChemicalSubstance (1->4)-alpha-D-glucan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15444 chebi_ph7_3 CHEBI:15447 biolink:ChemicalSubstance (1->4)-beta-D-xylan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15447 chebi_ph7_3 CHEBI:39418 biolink:ChemicalSubstance straight-chain saturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39418 CHEBI:39417 biolink:ChemicalSubstance branched-chain saturated fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39417 CHEBI:15446 biolink:ChemicalSubstance [(1->4)-alpha-D-galacturonosyl]n go-plus.json http://purl.obolibrary.org/obo/CHEBI_15446 CHEBI:15441 biolink:ChemicalSubstance (S)-2,3-epoxysqualene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15441 chebi_ph7_3 GO:0052483 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052483 GO:0052482 biolink:BiologicalProcess defense response by cell wall thickening A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism. go-plus.json cell wall thickening during defense response http://purl.obolibrary.org/obo/GO_0052482 CHEBI:15440 biolink:ChemicalSubstance squalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15440 chebi_ph7_3 GO:0052481 biolink:BiologicalProcess obsolete negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related symbiont SA-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052481 CHEBI:15443 biolink:ChemicalSubstance inulin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15443 GO:0052480 biolink:BiologicalProcess obsolete negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of defense-related symbiont JA-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052480 CHEBI:15442 biolink:ChemicalSubstance presqualene diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15442 GO:0052487 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont jasmonic acid-mediated defense response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json suppression by organism of symbiont JA-mediated defense response|negative regulation by organism of symbiont jasmonic acid-mediated defense response http://purl.obolibrary.org/obo/GO_0052487 CHEBI:39412 biolink:ChemicalSubstance bridged diphenyl acaricide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39412 GO:0052486 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont innate immunity OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the symbiont organism, the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of symbiont innate immunity|negative regulation of symbiont innate immune response http://purl.obolibrary.org/obo/GO_0052486 GO:0052485 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont inflammatory response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of symbiont inflammatory response http://purl.obolibrary.org/obo/GO_0052485 GO:0052484 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont ethylene-mediated defense response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json suppression by organism of symbiont ethylene-mediated defense response|negative regulation by organism of symbiont ethylene-mediated defense response http://purl.obolibrary.org/obo/GO_0052484 GO:0052499 biolink:BiologicalProcess obsolete pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. go-plus.json pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity http://purl.obolibrary.org/obo/GO_0052499 GO:1904249 biolink:BiologicalProcess negative regulation of age-related resistance Any process that stops, prevents or reduces the extent of age-related resistance. go-plus.json down-regulation of ARR|negative regulation of ARR|inhibition of flowering-induced resistance|down regulation of adult seedling resistance|negative regulation of senescence-induced resistance|down-regulation of mature seedling resistance|down-regulation of senescence-induced resistance|negative regulation of mature seedling resistance|downregulation of adult seedling resistance|inhibition of ARR|down-regulation of age-related resistance|negative regulation of flowering-induced resistance|down-regulation of flowering-induced resistance|downregulation of mature seedling resistance|down-regulation of adult seedling resistance|negative regulation of adult seedling resistance|inhibition of senescence-induced resistance|downregulation of age-related resistance|down regulation of ARR|down regulation of mature seedling resistance|down regulation of age-related resistance|downregulation of flowering-induced resistance|downregulation of ARR|inhibition of age-related resistance|down regulation of senescence-induced resistance|down regulation of flowering-induced resistance|inhibition of mature seedling resistance|inhibition of adult seedling resistance|downregulation of senescence-induced resistance http://purl.obolibrary.org/obo/GO_1904249 GO:1904248 biolink:BiologicalProcess regulation of age-related resistance Any process that modulates the extent of age-related resistance. go-plus.json regulation of adult seedling resistance|regulation of developmental resistance|regulation of mature seedling resistance|regulation of ontogenic resistance|regulation of ARR|regulation of flowering-induced resistance|regulation of senescence-induced resistance http://purl.obolibrary.org/obo/GO_1904248 GO:1904247 biolink:BiologicalProcess positive regulation of polynucleotide adenylyltransferase activity Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity. go-plus.json up regulation of terminal riboadenylate transferase activity|positive regulation of poly-A polymerase activity|activation of polynucleotide adenylyltransferase activity|upregulation of polyadenylate polymerase activity|up regulation of poly-A polymerase activity|activation of terminal riboadenylate transferase activity|positive regulation of RNA formation factors, PF1|upregulation of poly(A) hydrolase activity|positive regulation of terminal riboadenylate transferase activity|upregulation of poly(A) polymerase activity|upregulation of polyadenylate synthetase activity|up regulation of RNA formation factors, PF1|up-regulation of RNA adenylating enzyme activity|upregulation of ATP-polynucleotide adenylyltransferase activity|positive regulation of ATP:polynucleotidylexotransferase activity|upregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up regulation of polyadenylate nucleotidyltransferase activity|positive regulation of AMP polynucleotidylexotransferase activity|upregulation of poly(A) synthetase activity|upregulation of polyadenylic polymerase activity|up-regulation of polyadenylic acid polymerase activity|up regulation of ATP:polynucleotidylexotransferase activity|up regulation of NTP polymerase activity|activation of polyadenylate nucleotidyltransferase activity|positive regulation of polyadenylate nucleotidyltransferase activity|up regulation of AMP polynucleotidylexotransferase activity|up-regulation of ATP:polynucleotide adenylyltransferase activity|activation of NTP polymerase activity|positive regulation of NTP polymerase activity|up regulation of polyadenylate polymerase activity|up-regulation of poly(A) hydrolase activity|upregulation of poly-A polymerase activity|up-regulation of polynucleotide adenylyltransferase activity|activation of poly(A) hydrolase activity|positive regulation of polyadenylate polymerase activity|up-regulation of terminal riboadenylate transferase activity|activation of polyadenylate polymerase activity|upregulation of RNA formation factors, PF1|up regulation of polyadenylate synthetase activity|up regulation of poly(A) polymerase activity|upregulation of RNA adenylating enzyme activity|up-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of polyadenylic polymerase activity|positive regulation of polyadenylate synthetase activity|activation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|activation of poly(A) polymerase activity|positive regulation of poly(A) polymerase activity|activation of polyadenylate synthetase activity|upregulation of polyadenylic acid polymerase activity|positive regulation of ATP-polynucleotide adenylyltransferase activity|up regulation of poly(A) synthetase activity|activation of polyadenylic polymerase activity|activation of ATP-polynucleotide adenylyltransferase activity|upregulation of ATP:polynucleotide adenylyltransferase activity|upregulation of ATP:polynucleotidylexotransferase activity|up-regulation of polyadenylate nucleotidyltransferase activity|activation of poly(A) synthetase activity|upregulation of AMP polynucleotidylexotransferase activity|positive regulation of poly(A) synthetase activity|upregulation of polynucleotide adenylyltransferase activity|up-regulation of poly-A polymerase activity|up-regulation of NTP polymerase activity|upregulation of terminal riboadenylate transferase activity|positive regulation of poly(A) hydrolase activity|activation of poly-A polymerase activity|up-regulation of RNA formation factors, PF1|up regulation of poly(A) hydrolase activity|up-regulation of polyadenylate polymerase activity|up regulation of RNA adenylating enzyme activity|positive regulation of RNA adenylating enzyme activity|activation of RNA adenylating enzyme activity|positive regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up regulation of polyadenylic acid polymerase activity|positive regulation of polyadenylic polymerase activity|up-regulation of polyadenylate synthetase activity|up-regulation of poly(A) polymerase activity|up-regulation of ATP:polynucleotidylexotransferase activity|positive regulation of polyadenylic acid polymerase activity|activation of ATP:polynucleotidylexotransferase activity|activation of polyadenylic acid polymerase activity|up regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|upregulation of polyadenylate nucleotidyltransferase activity|up regulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of AMP polynucleotidylexotransferase activity|activation of AMP polynucleotidylexotransferase activity|activation of RNA formation factors, PF1|up regulation of polyadenylic polymerase activity|upregulation of NTP polymerase activity|positive regulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of poly(A) synthetase activity|activation of ATP:polynucleotide adenylyltransferase activity|up regulation of polynucleotide adenylyltransferase activity http://purl.obolibrary.org/obo/GO_1904247 GO:1904246 biolink:BiologicalProcess negative regulation of polynucleotide adenylyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity. go-plus.json negative regulation of polyadenylic acid polymerase activity|down-regulation of polyadenylic acid polymerase activity|downregulation of polyadenylic polymerase activity|down regulation of NTP polymerase activity|inhibition of poly(A) hydrolase activity|down-regulation of ATP:polynucleotidylexotransferase activity|down-regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of ATP:polynucleotidylexotransferase activity|down-regulation of AMP polynucleotidylexotransferase activity|downregulation of polyadenylate nucleotidyltransferase activity|negative regulation of AMP polynucleotidylexotransferase activity|down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of polyadenylic polymerase activity|down regulation of polyadenylate polymerase activity|downregulation of NTP polymerase activity|down-regulation of polynucleotide adenylyltransferase activity|inhibition of RNA adenylating enzyme activity|downregulation of poly-A polymerase activity|inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|negative regulation of terminal riboadenylate transferase activity|down-regulation of terminal riboadenylate transferase activity|inhibition of polyadenylic polymerase activity|down regulation of polyadenylate synthetase activity|inhibition of polyadenylic acid polymerase activity|downregulation of RNA formation factors, PF1|down regulation of poly(A) polymerase activity|downregulation of polyadenylate polymerase activity|down regulation of ATP-polynucleotide adenylyltransferase activity|inhibition of ATP:polynucleotide adenylyltransferase activity|down regulation of poly-A polymerase activity|down regulation of poly(A) synthetase activity|downregulation of ATP:polynucleotidylexotransferase activity|downregulation of poly(A) polymerase activity|downregulation of polyadenylate synthetase activity|inhibition of poly-A polymerase activity|down regulation of RNA formation factors, PF1|downregulation of ATP-polynucleotide adenylyltransferase activity|inhibition of polynucleotide adenylyltransferase activity|negative regulation of polyadenylate nucleotidyltransferase activity|downregulation of AMP polynucleotidylexotransferase activity|down-regulation of polyadenylate nucleotidyltransferase activity|inhibition of terminal riboadenylate transferase activity|downregulation of poly(A) synthetase activity|down-regulation of NTP polymerase activity|negative regulation of NTP polymerase activity|down regulation of ATP:polynucleotidylexotransferase activity|down regulation of AMP polynucleotidylexotransferase activity|negative regulation of polyadenylate polymerase activity|inhibition of ATP:polynucleotidylexotransferase activity|down regulation of RNA adenylating enzyme activity|down-regulation of polyadenylate polymerase activity|negative regulation of poly(A) hydrolase activity|down-regulation of poly(A) hydrolase activity|inhibition of AMP polynucleotidylexotransferase activity|inhibition of RNA formation factors, PF1|down regulation of polyadenylic acid polymerase activity|inhibition of polyadenylate nucleotidyltransferase activity|negative regulation of polyadenylate synthetase activity|negative regulation of poly(A) polymerase activity|down-regulation of polyadenylate synthetase activity|down-regulation of poly(A) polymerase activity|inhibition of NTP polymerase activity|down-regulation of ATP-polynucleotide adenylyltransferase activity|negative regulation of ATP-polynucleotide adenylyltransferase activity|downregulation of RNA adenylating enzyme activity|down regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|negative regulation of polyadenylic polymerase activity|down-regulation of polyadenylic polymerase activity|negative regulation of poly(A) synthetase activity|downregulation of polyadenylic acid polymerase activity|down-regulation of poly(A) synthetase activity|down regulation of polynucleotide adenylyltransferase activity|inhibition of polyadenylate polymerase activity|downregulation of ATP:polynucleotide adenylyltransferase activity|down regulation of terminal riboadenylate transferase activity|inhibition of poly(A) polymerase activity|inhibition of polyadenylate synthetase activity|downregulation of poly(A) hydrolase activity|negative regulation of poly-A polymerase activity|down-regulation of poly-A polymerase activity|inhibition of ATP-polynucleotide adenylyltransferase activity|downregulation of polynucleotide adenylyltransferase activity|downregulation of terminal riboadenylate transferase activity|negative regulation of RNA formation factors, PF1|down-regulation of RNA formation factors, PF1|negative regulation of RNA adenylating enzyme activity|down-regulation of RNA adenylating enzyme activity|inhibition of poly(A) synthetase activity|down regulation of polyadenylate nucleotidyltransferase activity|downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of poly(A) hydrolase activity http://purl.obolibrary.org/obo/GO_1904246 GO:1904245 biolink:BiologicalProcess regulation of polynucleotide adenylyltransferase activity Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity. go-plus.json regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|regulation of polyadenylate nucleotidyltransferase activity|regulation of polyadenylic polymerase activity|regulation of NTP polymerase activity|regulation of polyadenylate polymerase activity|regulation of poly-A polymerase activity|regulation of RNA formation factors, PF1|regulation of polyadenylate synthetase activity|regulation of poly(A) polymerase activity|regulation of ATP-polynucleotide adenylyltransferase activity|regulation of poly(A) synthetase activity|regulation of ATP:polynucleotidylexotransferase activity|regulation of AMP polynucleotidylexotransferase activity|regulation of RNA adenylating enzyme activity|regulation of polyadenylic acid polymerase activity|regulation of ATP:polynucleotide adenylyltransferase activity|regulation of terminal riboadenylate transferase activity|regulation of poly(A) hydrolase activity http://purl.obolibrary.org/obo/GO_1904245 GO:1904255 biolink:BiologicalProcess negative regulation of iron ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity. go-plus.json inhibition of iron cation channel activity|downregulation of iron channel activity|downregulation of iron-specific channel activity|down-regulation of iron channel activity|down regulation of iron-specific channel activity|inhibition of iron-specific channel activity|negative regulation of iron cation channel activity|inhibition of iron channel activity|down-regulation of iron cation channel activity|downregulation of iron cation channel activity|negative regulation of iron channel activity|negative regulation of iron-specific channel activity|down regulation of iron cation channel activity|down regulation of iron channel activity|down-regulation of iron-specific channel activity http://purl.obolibrary.org/obo/GO_1904255 CHEBI:15438 biolink:ChemicalSubstance coproporphyrinogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_15438 GO:1904254 biolink:BiologicalProcess regulation of iron ion transmembrane transporter activity Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity. go-plus.json regulation of iron-specific channel activity|regulation of iron channel activity|regulation of iron cation channel activity http://purl.obolibrary.org/obo/GO_1904254 CHEBI:15437 biolink:ChemicalSubstance uroporphyrinogen III go-plus.json http://purl.obolibrary.org/obo/CHEBI_15437 GO:1904253 biolink:BiologicalProcess positive regulation of bile acid metabolic process Any process that activates or increases the frequency, rate or extent of bile acid metabolic process. go-plus.json up-regulation of bile acid metabolism|activation of bile acid metabolism|up regulation of bile acid metabolic process|activation of bile acid metabolic process|positive regulation of bile acid metabolism|up regulation of bile acid metabolism|up-regulation of bile acid metabolic process|upregulation of bile acid metabolism|upregulation of bile acid metabolic process http://purl.obolibrary.org/obo/GO_1904253 CHEBI:40407 biolink:ChemicalSubstance 2-octaprenylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_40407 chebi_ph7_3 GO:1904252 biolink:BiologicalProcess negative regulation of bile acid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process. go-plus.json down regulation of bile acid metabolic process|downregulation of bile acid metabolic process|negative regulation of bile acid metabolism|down-regulation of bile acid metabolism|down-regulation of bile acid metabolic process|downregulation of bile acid metabolism|down regulation of bile acid metabolism|inhibition of bile acid metabolism|inhibition of bile acid metabolic process http://purl.obolibrary.org/obo/GO_1904252 CHEBI:15439 biolink:ChemicalSubstance coproporphyrinogen III go-plus.json http://purl.obolibrary.org/obo/CHEBI_15439 GO:1904251 biolink:BiologicalProcess regulation of bile acid metabolic process Any process that modulates the frequency, rate or extent of bile acid metabolic process. go-plus.json regulation of bile acid metabolism http://purl.obolibrary.org/obo/GO_1904251 GO:0052490 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052490 CHEBI:15434 biolink:ChemicalSubstance magnesium 13(1)-hydroxyprotoporphyrin 13-monomethyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_15434 GO:1904250 biolink:BiologicalProcess positive regulation of age-related resistance Any process that activates or increases the extent of age-related resistance. go-plus.json upregulation of senescence-induced resistance|upregulation of mature seedling resistance|up-regulation of adult seedling resistance|upregulation of age-related resistance|up regulation of ARR|positive regulation of ARR|activation of ARR|upregulation of flowering-induced resistance|up-regulation of mature seedling resistance|up regulation of senescence-induced resistance|upregulation of adult seedling resistance|positive regulation of senescence-induced resistance|up-regulation of age-related resistance|activation of age-related resistance|activation of mature seedling resistance|up-regulation of flowering-induced resistance|activation of senescence-induced resistance|up-regulation of ARR|positive regulation of mature seedling resistance|up regulation of adult seedling resistance|positive regulation of adult seedling resistance|up regulation of mature seedling resistance|activation of flowering-induced resistance|up-regulation of senescence-induced resistance|up regulation of age-related resistance|upregulation of ARR|positive regulation of flowering-induced resistance|activation of adult seedling resistance|up regulation of flowering-induced resistance http://purl.obolibrary.org/obo/GO_1904250 CHEBI:15433 biolink:ChemicalSubstance magnesium 13(1)-oxoprotoporphyrin 13-monomethyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_15433 CHEBI:15435 biolink:ChemicalSubstance protoporphyrinogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_15435 GO:0052494 biolink:BiologicalProcess occlusion by host of symbiont vascular system The process in which an organism reduces the flow of fluid within its symbiont's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052494 CHEBI:15430 biolink:ChemicalSubstance protoporphyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15430 GO:0052493 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052493 GO:0052492 biolink:BiologicalProcess obsolete negative regulation by host of symbiont signal transduction pathway OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json down regulation by host of symbiont signal transduction pathway|inhibition by host of symbiont signal transduction pathway|down-regulation by host of symbiont signal transduction pathway|negative modulation by organism of symbiont signal transduction pathway|downregulation by host of symbiont signal transduction pathway http://purl.obolibrary.org/obo/GO_0052492 CHEBI:15432 biolink:ChemicalSubstance magnesium protoporphyrin 13-monomethyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_15432 GO:0052491 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont salicylic acid-mediated defense response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json suppression by organism of symbiont salicylic acid-mediated defense response|suppression of symbiont SA mediated defense response|negative regulation by organism of symbiont salicylic acid-mediated defense response|negative regulation of symbiont SA-mediated defense response http://purl.obolibrary.org/obo/GO_0052491 CHEBI:15431 biolink:ChemicalSubstance magnesium protoporphyrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15431 GO:0052498 biolink:BiologicalProcess obsolete pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. go-plus.json general elicitor-dependent induction of symbiont innate immunity|MAMP dependent induction of symbiont innate immunity|PAMP dependent induction of symbiont innate immunity|pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity|pathogen-associated molecular pattern dependent activation by organism of symbiont innate immunity|PAMP dependent activation of symbiont innate immunity|MAMP dependent activation of symbiont innate immunity|general elicitor-dependent activation of symbiont innate immunity http://purl.obolibrary.org/obo/GO_0052498 GO:0052497 biolink:BiologicalProcess occlusion by organism of xylem in other organism involved in symbiotic interaction The process in which an organism reduces the flow of fluid within the xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves, of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json occlusion by organism of xylem in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052497 GO:0052496 biolink:BiologicalProcess occlusion by host of symbiont xylem The process in which an organism reduces the flow of fluid within the symbiont xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052496 GO:0052495 biolink:BiologicalProcess occlusion by organism of vascular system in other organism involved in symbiotic interaction The process in which an organism reduces the flow of fluid within its second organism's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant, where the two organisms are in a symbiotic interaction. go-plus.json occlusion by organism of vascular system in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052495 GO:1904259 biolink:BiologicalProcess regulation of basement membrane assembly involved in embryonic body morphogenesis Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904259 GO:1904258 biolink:BiologicalProcess nuclear dicing body assembly The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body. go-plus.json D body formation|D body assembly|nuclear dicing body formation http://purl.obolibrary.org/obo/GO_1904258 GO:1904257 biolink:BiologicalProcess zinc ion import into Golgi apparatus The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi apparatus. go-plus.json zinc ion import into Golgi membrane|zinc II ion import across Golgi membrane|zinc ion import across Golgi membrane|zinc(2+) import across Golgi membrane http://purl.obolibrary.org/obo/GO_1904257 GO:1904256 biolink:BiologicalProcess positive regulation of iron ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity. go-plus.json upregulation of iron cation channel activity|positive regulation of iron-specific channel activity|up regulation of iron-specific channel activity|up regulation of iron channel activity|positive regulation of iron transmembrane transporter activity|activation of iron channel activity|up-regulation of iron cation channel activity|activation of iron cation channel activity|upregulation of iron-specific channel activity|up-regulation of iron channel activity|positive regulation of iron cation channel activity|up regulation of iron cation channel activity|up-regulation of iron-specific channel activity|activation of iron-specific channel activity|positive regulation of iron channel activity|upregulation of iron channel activity http://purl.obolibrary.org/obo/GO_1904256 GO:1904266 biolink:BiologicalProcess regulation of Schwann cell chemotaxis Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_1904266 UBERON:0007037 biolink:AnatomicalEntity mechanosensory system go-plus.json http://purl.obolibrary.org/obo/UBERON_0007037 GO:1904265 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904265 GO:1904264 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904264 GO:1904263 biolink:BiologicalProcess positive regulation of TORC1 signaling Any process that activates or increases the frequency, rate or extent of TORC1 signaling. go-plus.json up-regulation of TORC1 signaling|up-regulation of TORC1 signal transduction|upregulation of TORC1 signaling|upregulation of TORC1 signal transduction|up regulation of TORC1 signaling|activation of TORC1 signaling|up regulation of TORC1 signal transduction|activation of TORC1 signal transduction|positive regulation of TORC1 signal transduction http://purl.obolibrary.org/obo/GO_1904263 GO:1904262 biolink:BiologicalProcess negative regulation of TORC1 signaling Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling. go-plus.json negative regulation of TORC1 signal transduction|down-regulation of TORC1 signal transduction|inhibition of TORC1 signaling|inhibition of TORC1 signal transduction|down regulation of TORC1 signaling|downregulation of TORC1 signaling|down regulation of TORC1 signal transduction|downregulation of TORC1 signal transduction|down-regulation of TORC1 signaling http://purl.obolibrary.org/obo/GO_1904262 CHEBI:15467 biolink:ChemicalSubstance (3S)-3-hydroxy-3-methylglutaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15467 GO:1904261 biolink:BiologicalProcess positive regulation of basement membrane assembly involved in embryonic body morphogenesis Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis. go-plus.json upregulation of basement membrane assembly involved in embryonic body morphogenesis|up regulation of basement membrane assembly involved in embryonic body morphogenesis|activation of basement membrane assembly involved in embryonic body morphogenesis|up-regulation of basement membrane assembly involved in embryonic body morphogenesis http://purl.obolibrary.org/obo/GO_1904261 CHEBI:15466 biolink:ChemicalSubstance (S)-methylmalonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15466 GO:1904260 biolink:BiologicalProcess negative regulation of basement membrane assembly involved in embryonic body morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis. go-plus.json down regulation of basement membrane assembly involved in embryonic body morphogenesis|downregulation of basement membrane assembly involved in embryonic body morphogenesis|down-regulation of basement membrane assembly involved in embryonic body morphogenesis|inhibition of basement membrane assembly involved in embryonic body morphogenesis http://purl.obolibrary.org/obo/GO_1904260 CHEBI:15469 biolink:ChemicalSubstance alk-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15469 CHEBI:15468 biolink:ChemicalSubstance 3'-dephospho-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15468 CHEBI:15463 biolink:ChemicalSubstance cinnamoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15463 CHEBI:15465 biolink:ChemicalSubstance (R)-methylmalonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15465 CHEBI:15464 biolink:ChemicalSubstance (E,E)-piperonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15464 CHEBI:15461 biolink:ChemicalSubstance cis-tetradec-11-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15461 CHEBI:15460 biolink:ChemicalSubstance trans-tetradec-11-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15460 GO:1904269 biolink:CellularComponent cell leading edge cell cortex The cell cortex of the leading edge of a cell. go-plus.json peripheral cytoplasm of cell leading edge|cell periphery of cell leading edge|peripheral cytoplasm of front of cell|cell periphery of front of cell|peripheral cytoplasm of leading edge of cell|cell periphery of leading edge of cell|cell cortex of cell leading edge|cell cortex of front of cell|cell cortex of leading edge of cell http://purl.obolibrary.org/obo/GO_1904269 GO:1904268 biolink:BiologicalProcess positive regulation of Schwann cell chemotaxis Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis. go-plus.json up regulation of Schwann cell chemotaxis|activation of Schwann cell chemotaxis|up-regulation of Schwann cell chemotaxis|upregulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1904268 GO:1904267 biolink:BiologicalProcess negative regulation of Schwann cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis. go-plus.json downregulation of Schwann cell chemotaxis|down-regulation of Schwann cell chemotaxis|inhibition of Schwann cell chemotaxis|down regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1904267 GO:1904277 biolink:BiologicalProcess negative regulation of wax biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process. go-plus.json down regulation of wax biosynthesis|down regulation of wax biosynthetic process|down regulation of wax formation|inhibition of wax biosynthetic process|inhibition of wax biosynthesis|downregulation of wax synthesis|downregulation of wax formation|down-regulation of wax anabolism|negative regulation of wax anabolism|down-regulation of wax synthesis|negative regulation of wax synthesis|inhibition of wax anabolism|down-regulation of wax formation|negative regulation of wax formation|inhibition of wax synthesis|down-regulation of wax biosynthetic process|negative regulation of wax biosynthesis|down-regulation of wax biosynthesis|inhibition of wax formation|down regulation of wax anabolism|downregulation of wax biosynthetic process|downregulation of wax biosynthesis|down regulation of wax synthesis|downregulation of wax anabolism http://purl.obolibrary.org/obo/GO_1904277 UBERON:0007026 biolink:AnatomicalEntity presumptive gut go-plus.json primordial gut|primordial digestive tube|embryonic digestive tube|future digestive tube|primitive gut|future digestive tract|future gut http://purl.obolibrary.org/obo/UBERON_0007026 GO:1904276 biolink:BiologicalProcess regulation of wax biosynthetic process Any process that modulates the frequency, rate or extent of wax biosynthetic process. go-plus.json regulation of wax formation|regulation of wax anabolism|regulation of wax biosynthesis|regulation of wax synthesis http://purl.obolibrary.org/obo/GO_1904276 CHEBI:15459 biolink:ChemicalSubstance (3S)-citryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15459 GO:1904275 biolink:BiologicalProcess tricellular tight junction disassembly The disaggregation of a tricellular tight junction into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_1904275 GO:1904274 biolink:BiologicalProcess tricellular tight junction assembly The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction. go-plus.json tricellular tight junction formation http://purl.obolibrary.org/obo/GO_1904274 UBERON:0007023 biolink:AnatomicalEntity adult organism A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage. go-plus.json adults|adult http://purl.obolibrary.org/obo/UBERON_0007023 GO:1904273 biolink:BiologicalProcess L-alanine import across plasma membrane The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1904273 CHEBI:15456 biolink:ChemicalSubstance (R)-3-hydroxyacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15456 UBERON:0007021 biolink:AnatomicalEntity sexually immature organism A multicellular organism that is at the juvenile stage. go-plus.json juveniles|juvenile organism|juvenile http://purl.obolibrary.org/obo/UBERON_0007021 GO:1904272 biolink:BiologicalProcess L-tryptophan import across plasma membrane The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_1904272 CHEBI:15455 biolink:ChemicalSubstance (S)-3-hydroxyacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15455 GO:1904271 biolink:BiologicalProcess L-proline import across plasma membrane The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json L-proline import into cell http://purl.obolibrary.org/obo/GO_1904271 CHEBI:15457 biolink:ChemicalSubstance citramalyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15457 GO:1904270 biolink:BiologicalProcess pyroptosome complex assembly The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex. go-plus.json ASC pyroptosome assembly|ASC pyroptosome formation|pyroptosome complex formation http://purl.obolibrary.org/obo/GO_1904270 CHEBI:15452 biolink:ChemicalSubstance (R)-3-hydroxybutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15452 CHEBI:15451 biolink:ChemicalSubstance (2S)-2-methylacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15451 CHEBI:15454 biolink:ChemicalSubstance (3S)-3-carboxy-3-hydroxypropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15454 CHEBI:15453 biolink:ChemicalSubstance (S)-3-hydroxybutanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15453 CHEBI:15450 biolink:ChemicalSubstance (2R)-2-methylacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15450 GO:0003436 biolink:BiologicalProcess regulation of cell adhesion involved in growth plate cartilage morphogenesis Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone. go-plus.json http://purl.obolibrary.org/obo/GO_0003436 GO:0003435 biolink:BiologicalProcess smoothened signaling pathway involved in growth plate cartilage chondrocyte development The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time. go-plus.json hedgehog signaling pathway involved in growth plate cartilage chondrocyte development|hh signaling pathway involved in growth plate cartilage chondrocyte development|smoothened signalling pathway involved in growth plate cartilage chondrocyte development http://purl.obolibrary.org/obo/GO_0003435 GO:0003437 biolink:BiologicalProcess regulation of cell communication involved in growth plate cartilage morphogenesis Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_0003437 GO:0003432 biolink:BiologicalProcess cell growth involved in growth plate cartilage chondrocyte morphogenesis The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time. go-plus.json http://purl.obolibrary.org/obo/GO_0003432 GO:0003431 biolink:BiologicalProcess growth plate cartilage chondrocyte development The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003431 CHEBI:64381 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64381 chebi_ph7_3 CHEBI:88351 biolink:ChemicalSubstance linoleoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88351 chebi_ph7_3 GO:0003434 biolink:BiologicalProcess BMP signaling pathway involved in growth plate cartilage chondrocyte development A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of a growth plate cartilage chondrocyte over time. go-plus.json BMP signalling pathway involved in growth plate cartilage chondrocyte development http://purl.obolibrary.org/obo/GO_0003434 CHEBI:88350 biolink:ChemicalSubstance 2-phosphoglycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88350 chebi_ph7_3 GO:0003433 biolink:BiologicalProcess chondrocyte development involved in endochondral bone morphogenesis The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. go-plus.json http://purl.obolibrary.org/obo/GO_0003433 GO:0003430 biolink:BiologicalProcess growth plate cartilage chondrocyte growth The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another. go-plus.json growth plate cartilage chondrocyte hypertrophy http://purl.obolibrary.org/obo/GO_0003430 PR:000002112 biolink:Protein vascular endothelial growth factor receptor 2 A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. go-plus.json protein-tyrosine kinase receptor flk-1|CD309|KDR|kinase insert domain receptor|fetal liver kinase 1|VEGFR-2|FLK-1|FLK1|kinase NYK http://purl.obolibrary.org/obo/PR_000002112 NCBITaxon:1963758 biolink:OrganismalEntity Myomorpha go-plus.json Sciurognathi|mice and others http://purl.obolibrary.org/obo/NCBITaxon_1963758 NCBITaxon:3176 biolink:OrganismalEntity Zygnematales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3176 CHEBI:64397 biolink:ChemicalSubstance asperfuranone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64397 chebi_ph7_3 CHEBI:64396 biolink:ChemicalSubstance 1-oleyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64396 chebi_ph7_3 CHEBI:88347 biolink:ChemicalSubstance 15(S)-HEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_88347 CHEBI:64398 biolink:ChemicalSubstance monodictyphenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64398 PR:000002122 biolink:Protein C-C motif chemokine 2 An eotaxin-like cytokine that is a translation product of the human CCL2 gene or a 1:1 ortholog thereof. go-plus.json platelet-derived growth factor-inducible protein JE|monocyte secretory protein JE|CCL2|monocyte chemoattractant protein 1|small-inducible cytokine A2|MCAF|HC11|monocyte chemotactic and activating factor|monocyte chemotactic protein 1|Je|SCYA2|MCP-1|MCP1 http://purl.obolibrary.org/obo/PR_000002122 PR:000002125 biolink:Protein C-C motif chemokine 7 An eotaxin-like cytokine that is a translation product of the human CCL7 gene or a 1:1 ortholog thereof. go-plus.json small-inducible cytokine A7|monocyte chemoattractant protein 3|intercrine/chemokine MARC|protein FIC|MCP-3|Fic|NC28|monocyte chemotactic protein 3|SCYA7|SCYA6|MCP3|CCL7 http://purl.obolibrary.org/obo/PR_000002125 GO:0003414 biolink:BiologicalProcess chondrocyte morphogenesis involved in endochondral bone morphogenesis The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003414 GO:0003413 biolink:BiologicalProcess chondrocyte differentiation involved in endochondral bone morphogenesis The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_0003413 GO:0003416 biolink:BiologicalProcess endochondral bone growth The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. go-plus.json http://purl.obolibrary.org/obo/GO_0003416 GO:0003415 biolink:BiologicalProcess chondrocyte hypertrophy The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time. go-plus.json http://purl.obolibrary.org/obo/GO_0003415 GO:0003410 biolink:BiologicalProcess anterior rotation of the optic cup A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis. go-plus.json http://purl.obolibrary.org/obo/GO_0003410 GO:0003412 biolink:BiologicalProcess establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0003412 GO:0003411 biolink:BiologicalProcess cell motility involved in camera-type eye morphogenesis Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0003411 NCBITaxon:590 biolink:OrganismalEntity Salmonella go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_590 GO:0003418 biolink:BiologicalProcess growth plate cartilage chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. go-plus.json http://purl.obolibrary.org/obo/GO_0003418 GO:0003417 biolink:BiologicalProcess growth plate cartilage development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. go-plus.json http://purl.obolibrary.org/obo/GO_0003417 GO:0003419 biolink:BiologicalProcess growth plate cartilage chondrocyte proliferation The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0003419 GO:0003425 biolink:BiologicalProcess establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate. go-plus.json http://purl.obolibrary.org/obo/GO_0003425 GO:0003424 biolink:BiologicalProcess establishment of cell polarity involved in growth plate cartilage chondrocyte division The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte. go-plus.json growth plate cartilage chondrocyte polarization http://purl.obolibrary.org/obo/GO_0003424 GO:0003427 biolink:BiologicalProcess regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell. go-plus.json regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division by planar cell polarity pathway http://purl.obolibrary.org/obo/GO_0003427 CHEBI:146500 biolink:ChemicalSubstance D-Galp-(1->3)-D-GalpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_146500 chebi_ph7_3 GO:0003426 biolink:BiologicalProcess cytoskeleton polarization involved in growth plate cartilage chondrocyte division A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0003426 GO:0003421 biolink:BiologicalProcess growth plate cartilage axis specification The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth. go-plus.json growth plate cartilage axis determination http://purl.obolibrary.org/obo/GO_0003421 CHEBI:88360 biolink:ChemicalSubstance N-(1-naphthyl)carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_88360 chebi_ph7_3 GO:0003420 biolink:BiologicalProcess regulation of growth plate cartilage chondrocyte proliferation Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0003420 GO:0003423 biolink:BiologicalProcess growth plate cartilage chondrocyte division The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate. go-plus.json http://purl.obolibrary.org/obo/GO_0003423 GO:0003422 biolink:BiologicalProcess growth plate cartilage morphogenesis The process in which the anatomical structures of growth plate cartilage are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003422 CHEBI:88361 biolink:ChemicalSubstance N-(naphthyl)carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_88361 PR:000002107 biolink:Protein tumor necrosis factor ligand superfamily member 11 A tumor necrosis factor ligand superfamily member 10/11 that is a translation product of the human TNFSF11 gene or a 1:1 ortholog thereof. go-plus.json TRANCE|osteoclast differentiation factor|receptor activator of nuclear factor kappa-B ligand|OPGL|RANKL|TNFSF11|TNF-related activation-induced cytokine|osteoprotegerin ligand|ODF|CD254 http://purl.obolibrary.org/obo/PR_000002107 PR:000002106 biolink:Protein tumor necrosis factor ligand superfamily member 10 A tumor necrosis factor ligand superfamily member 10/11 that is a translation product of the human TNFSF10 gene or a 1:1 ortholog thereof. go-plus.json protein TRAIL|apo-2 ligand|TNF-related apoptosis-inducing ligand|apo-2L|TRAIL|TNFSF10|APO2L|CD253 http://purl.obolibrary.org/obo/PR_000002106 PR:000002109 biolink:Protein tumor necrosis factor receptor superfamily member 10B A tumor necrosis factor receptor superfamily member 10A/B that is a translation product of the human TNFRSF10B gene or a 1:1 ortholog thereof. go-plus.json CD262|TNFRSF10B|TRAIL receptor 2|TRAIL-R2|TNF-related apoptosis-inducing ligand receptor 2|KILLER|DR5|TRAILR2|death receptor 5|TRICK2|MK|ZTNFR9 http://purl.obolibrary.org/obo/PR_000002109 NCBITaxon:3166 biolink:OrganismalEntity Chlorophyceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3166 PR:000002108 biolink:Protein tumor necrosis factor receptor superfamily member 10A A tumor necrosis factor receptor superfamily member 10A/B that is a translation product of the human TNFRSF10A gene or a 1:1 ortholog thereof. No mouse gene has been assigned this name. go-plus.json APO2|CD261|TNFRSF10A|TRAIL receptor 1|TNF-related apoptosis-inducing ligand receptor 1|TRAIL-R1|DR4|TRAILR1|death receptor 4 http://purl.obolibrary.org/obo/PR_000002108 GO:0003429 biolink:BiologicalProcess growth plate cartilage chondrocyte morphogenesis The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0003429 GO:0003428 biolink:BiologicalProcess chondrocyte intercalation involved in growth plate cartilage morphogenesis The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone. go-plus.json http://purl.obolibrary.org/obo/GO_0003428 GO:0052403 biolink:BiologicalProcess negative regulation by host of symbiont catalytic activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by host of symbiont molecular function|down-regulation by host of symbiont enzyme activity|negative regulation by host of symbiont enzyme activity|down regulation by host of symbiont protein function|inhibition of symbiont enzyme activity|downregulation by host of symbiont protein function|downregulation by host of symbiont enzyme activity|inhibition by host of symbiont protein function|inhibition of symbiont protein function|down regulation by host of symbiont enzyme activity|inhibition by host of symbiont enzyme activity|down-regulation by host of symbiont protein function http://purl.obolibrary.org/obo/GO_0052403 GO:0052402 biolink:BiologicalProcess obsolete induction by organism of symbiont resistance gene-dependent defense response OBSOLETE. The activation by an organism of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of defense response in symbiont by specific elicitors|induction by organism of symbiont resistance gene-dependent defense response|activation by organism of symbiont gene-for-gene resistance|induction by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|induction by organism of symbiont gene-for-gene resistance|activation by organism of defense response in symbiont by specific elicitors|activation by organism of symbiont resistance gene-dependent defense response|activation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont http://purl.obolibrary.org/obo/GO_0052402 GO:0052401 biolink:BiologicalProcess obsolete induction by organism of defense-related symbiont reactive oxygen species production OBSOLETE. The activation by an organism of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of defense-related symbiont ROI production|activation by organism of defense-related symbiont reactive oxygen intermediate production|induction by organism of defense-related symbiont reactive oxygen species production|activation by organism of defense-related symbiont reactive oxidative species production|induction by organism of defense-related symbiont AOS production|activation by organism of defense-related symbiont oxidative burst|induction by organism of defense-related symbiont metabolic burst|activation by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont ROI production|induction by organism of defense-related symbiont respiratory burst|activation by organism of defense-related symbiont metabolic burst|induction by organism of defense-related symbiont reactive oxygen intermediate production|induction by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont reactive oxygen species production|activation by organism of defense-related symbiont AOS production|induction by organism of defense-related symbiont oxidative burst|activation by organism of defense-related symbiont respiratory burst http://purl.obolibrary.org/obo/GO_0052401 GO:0052400 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052400 CHEBI:88390 biolink:ChemicalSubstance 1-hydroxybutan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_88390 chebi_ph7_3 GO:0052407 biolink:BiologicalProcess obsolete metabolism by organism of carbohydrate in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of carbohydrate in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052407 GO:0052406 biolink:BiologicalProcess obsolete metabolism by host of symbiont carbohydrate OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052406 GO:0052405 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052405 GO:0052404 biolink:BiologicalProcess obsolete negative regulation by host of symbiont peptidase activity OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json downregulation by host of symbiont protease activity|down regulation by host of symbiont protease activity|inhibition by host of symbiont protease activity|negative regulation by host of symbiont protease activity|down-regulation by host of symbiont protease activity|inhibition of symbiont protease activity http://purl.obolibrary.org/obo/GO_0052404 GO:0052409 biolink:BiologicalProcess obsolete metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of cell wall cellulose in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052409 GO:0052408 biolink:BiologicalProcess obsolete metabolism by host of symbiont cell wall cellulose OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052408 GO:0003403 biolink:BiologicalProcess optic vesicle formation The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. go-plus.json http://purl.obolibrary.org/obo/GO_0003403 GO:0052414 biolink:BiologicalProcess obsolete metabolism by host of symbiont glucan OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052414 GO:0003402 biolink:BiologicalProcess planar cell polarity pathway involved in axis elongation The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0003402 GO:0052413 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052413 GO:0003405 biolink:BiologicalProcess optic vesicle elongation The developmental growth that results in the lengthening of the optic vesicle in the posterior direction. go-plus.json http://purl.obolibrary.org/obo/GO_0003405 GO:0052412 biolink:BiologicalProcess obsolete metabolism by host of symbiont cell wall pectin OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052412 GO:0003404 biolink:BiologicalProcess optic vesicle morphogenesis The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. go-plus.json http://purl.obolibrary.org/obo/GO_0003404 GO:0052411 biolink:BiologicalProcess obsolete metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of cell wall chitin in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052411 GO:0052418 biolink:BiologicalProcess obsolete metabolism by organism of protein in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of protein in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052418 PR:000016798 biolink:Protein titin A protein that is a translation product of the human TTN gene or a 1:1 ortholog thereof. go-plus.json connectin|TTN|rhabdomyosarcoma antigen MU-RMS-40.14 http://purl.obolibrary.org/obo/PR_000016798 GO:0052417 biolink:BiologicalProcess obsolete metabolism by host of symbiont protein OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052417 GO:0003401 biolink:BiologicalProcess axis elongation The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure. go-plus.json elongation of an axis http://purl.obolibrary.org/obo/GO_0003401 GO:0052416 biolink:BiologicalProcess obsolete metabolism by host of symbiont macromolecule OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052416 GO:0003400 biolink:BiologicalProcess regulation of COPII vesicle coating Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat. go-plus.json http://purl.obolibrary.org/obo/GO_0003400 GO:0052415 biolink:BiologicalProcess obsolete metabolism by organism of glucan in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of glucan in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052415 GO:0052419 biolink:BiologicalProcess obsolete metabolism by host of substance in symbiont OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052419 CHEBI:15397 biolink:ChemicalSubstance (S)-camphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_15397 chebi_ph7_3 CHEBI:15396 biolink:ChemicalSubstance (R)-camphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_15396 chebi_ph7_3 CHEBI:15399 biolink:ChemicalSubstance (+)-carvone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15399 chebi_ph7_3 CHEBI:15398 biolink:ChemicalSubstance (+)-exo-5-hydroxycamphor go-plus.json http://purl.obolibrary.org/obo/CHEBI_15398 chebi_ph7_3 GO:0052410 biolink:BiologicalProcess obsolete metabolism by host of symbiont cell wall chitin OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052410 CHEBI:15393 biolink:ChemicalSubstance (+)-borneol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15393 chebi_ph7_3 GO:0003407 biolink:BiologicalProcess neural retina development The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. go-plus.json http://purl.obolibrary.org/obo/GO_0003407 GO:0003406 biolink:BiologicalProcess retinal pigment epithelium development The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells. go-plus.json RPE development http://purl.obolibrary.org/obo/GO_0003406 CHEBI:15392 biolink:ChemicalSubstance (1R)-bornane-2,5-dione go-plus.json http://purl.obolibrary.org/obo/CHEBI_15392 chebi_ph7_3 GO:0003409 biolink:BiologicalProcess optic cup structural organization The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure. go-plus.json optic cup structural organisation http://purl.obolibrary.org/obo/GO_0003409 CHEBI:15395 biolink:ChemicalSubstance (+)-bornyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15395 CHEBI:15394 biolink:ChemicalSubstance (-)-borneol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15394 chebi_ph7_3 GO:0003408 biolink:BiologicalProcess optic cup formation involved in camera-type eye development The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0003408 GO:0052425 biolink:BiologicalProcess obsolete modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type II secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system http://purl.obolibrary.org/obo/GO_0052425 GO:0052424 biolink:BiologicalProcess obsolete modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type III secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system http://purl.obolibrary.org/obo/GO_0052424 GO:0052423 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052423 GO:0052422 biolink:BiologicalProcess modulation by host of symbiont catalytic activity The process in which a host organism effects a change in the enzyme activity of its symbiont organism. go-plus.json modulation by host of symbiont molecular function|modulation by host of symbiont enzyme activity http://purl.obolibrary.org/obo/GO_0052422 GO:0052429 biolink:BiologicalProcess obsolete modulation by organism of symbiont B-cell mediated immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont B-cell mediated immune response|regulation by organism of symbiont B-cell mediated immune response http://purl.obolibrary.org/obo/GO_0052429 GO:0052428 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052428 GO:0052427 biolink:BiologicalProcess obsolete modulation by host of symbiont peptidase activity OBSOLETE. The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by host of symbiont protease activity http://purl.obolibrary.org/obo/GO_0052427 GO:0052426 biolink:BiologicalProcess obsolete modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type IV secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system http://purl.obolibrary.org/obo/GO_0052426 CHEBI:40356 biolink:ChemicalSubstance N-acetyl-alpha-D-galactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_40356 chebi_ph7_3 CHEBI:39352 biolink:ChemicalSubstance dinitrophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_39352 GO:0052421 biolink:BiologicalProcess obsolete metabolism by organism of xylan in other organism involved in symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within a second organism, where the two organisms are in a symbiotic interaction. go-plus.json metabolism by organism of xylan in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052421 NCBITaxon:3193 biolink:OrganismalEntity Embryophyta go-plus.json land plants|higher plants|land plants|plants http://purl.obolibrary.org/obo/NCBITaxon_3193 GO:0052420 biolink:BiologicalProcess obsolete metabolism by host of symbiont xylan OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052420 GO:0052436 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the symbiont calcium-dependent protein kinase signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway|modulation by organism of defense-related symbiont CDPK pathway http://purl.obolibrary.org/obo/GO_0052436 GO:0052435 biolink:BiologicalProcess obsolete modulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation of defense-related symbiont MAPK-mediated signal transduction pathway by organism|modulation of defense-related symbiont mitogen activated protein kinase-mediated signal transduction pathway by organism http://purl.obolibrary.org/obo/GO_0052435 GO:0052434 biolink:BiologicalProcess obsolete modulation by organism of symbiont cell-mediated immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of any form of cell-based immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont cell-based immune response|modulation by organism of symbiont cell-mediated immune response http://purl.obolibrary.org/obo/GO_0052434 GO:0052433 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052433 GO:0052439 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont cell wall callose deposition OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont cell wall callose deposition http://purl.obolibrary.org/obo/GO_0052439 GO:0052438 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont callose deposition OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont callose deposition http://purl.obolibrary.org/obo/GO_0052438 GO:0052437 biolink:BiologicalProcess obsolete modulation by organism of defense-related symbiont calcium ion flux OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of defense-related symbiont calcium ion flux|modulation by organism of defense-related symbiont Ca2+ flux http://purl.obolibrary.org/obo/GO_0052437 CHEBI:39362 biolink:ChemicalSubstance mononitrophenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_39362 GO:0052432 biolink:BiologicalProcess obsolete modulation by organism of symbiont apoptosis OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont apoptosis|modulation by organism of symbiont apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052432 GO:0052431 biolink:BiologicalProcess obsolete modulation by organism of symbiont T-cell mediated immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of a symbiont organism, where the two organisms are in a symbiotic interaction. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont T-cell mediated immune response http://purl.obolibrary.org/obo/GO_0052431 GO:0052430 biolink:BiologicalProcess modulation by host of symbiont RNA levels The alteration by an organism of the levels of RNA in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0052430 CHEBI:78947 biolink:ChemicalSubstance archaeal metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_78947 CHEBI:78948 biolink:ChemicalSubstance L-2-amino-3-oxobutanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78948 chebi_ph7_3 CHEBI:64302 biolink:ChemicalSubstance cyanamide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64302 CHEBI:64307 biolink:ChemicalSubstance 2,4-diaminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64307 CHEBI:78940 biolink:ChemicalSubstance N-palmitoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78940 CHEBI:64315 biolink:ChemicalSubstance 4-demethylwyosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_64315 chebi_ph7_3 CHEBI:78954 biolink:ChemicalSubstance (omega-1)-hydroxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78954 CHEBI:64328 biolink:ChemicalSubstance lysidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64328 CHEBI:78978 biolink:ChemicalSubstance (11R)-11-hydroxylauric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78978 CHEBI:64335 biolink:ChemicalSubstance N(1)-aminopropylagmatine(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64335 chebi_ph7_3 CHEBI:64339 biolink:ChemicalSubstance N(1)-aminoaminopropylagmatine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64339 CHEBI:78988 biolink:ChemicalSubstance O-[S-(3R)-hydroxynonanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78988 chebi_ph7_3 PR:000016724 biolink:Protein thyrotropin subunit beta A glycoprotein hormone beta chain that is a translation product of the human TSHB gene or a 1:1 ortholog thereof. go-plus.json thyrotropin alfa|TSH-B|TSHB|TSH-beta|thyrotropin beta chain|thyroid-stimulating hormone subunit beta http://purl.obolibrary.org/obo/PR_000016724 CHEBI:64345 biolink:ChemicalSubstance MALDI matrix material go-plus.json http://purl.obolibrary.org/obo/CHEBI_64345 CHEBI:64344 biolink:ChemicalSubstance 2',4',6'-trihydroxyacetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64344 chebi_ph7_3 CHEBI:78983 biolink:ChemicalSubstance O-[S-(3R)-hydroxypentanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78983 chebi_ph7_3 CHEBI:78981 biolink:ChemicalSubstance UDP-2-acetamido-2-deoxy-3-dehydro-alpha-D-glucopyranose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78981 chebi_ph7_3 CHEBI:78987 biolink:ChemicalSubstance O-[S-(3R)-hydroxyheptanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78987 chebi_ph7_3 CHEBI:78986 biolink:ChemicalSubstance O-[S-(3R)-hydroxy-5-methylhexanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78986 chebi_ph7_3 CHEBI:78985 biolink:ChemicalSubstance O-[S-(3R)-hydroxy-4-methylhexanoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78985 chebi_ph7_3 NCBITaxon:543 biolink:OrganismalEntity Enterobacteriaceae go-plus.json enterobacteria|gamma-3 proteobacteria|Enterobacteraceae http://purl.obolibrary.org/obo/NCBITaxon_543 CHEBI:64353 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-glucosamine 3-phosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64353 chebi_ph7_3 CHEBI:64351 biolink:ChemicalSubstance beta-D-Manp-(1->4)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_64351 chebi_ph7_3 CHEBI:88306 biolink:ChemicalSubstance 4-nitrophenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_88306 CHEBI:8927 biolink:ChemicalSubstance S-(2,4-dinitrophenyl)glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_8927 CHEBI:78994 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-D-myo-inositol-3',5'-bisphosphate)(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78994 chebi_ph7_3 CHEBI:78993 biolink:ChemicalSubstance 1,2-dipalmitoylglycero-3-phospho-(1'-D-myo-inositol-3'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78993 chebi_ph7_3 CHEBI:78995 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78995 chebi_ph7_3 CHEBI:64362 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-glucosamine 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64362 CHEBI:88332 biolink:ChemicalSubstance aralkylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_88332 chebi_ph7_3 CHEBI:64361 biolink:ChemicalSubstance beta-sesquiphellandrene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64361 chebi_ph7_3 CHEBI:64368 biolink:ChemicalSubstance 3-hydroxyproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_64368 CHEBI:64365 biolink:ChemicalSubstance aralkylamino compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_64365 CHEBI:64373 biolink:ChemicalSubstance emericellamide A go-plus.json http://purl.obolibrary.org/obo/CHEBI_64373 chebi_ph7_3 NCBITaxon:562 biolink:OrganismalEntity Escherichia coli go-plus.json Enterococcus coli|Bacillus coli|E. coli|Bacterium coli|Bacterium coli commune|Escherichia/Shigella coli http://purl.obolibrary.org/obo/NCBITaxon_562 CHEBI:64372 biolink:ChemicalSubstance emericellamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64372 CHEBI:64379 biolink:ChemicalSubstance 1-acyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64379 chebi_ph7_3 NCBITaxon:561 biolink:OrganismalEntity Escherichia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_561 CHEBI:30924 biolink:ChemicalSubstance L-tartrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30924 chebi_ph7_3 CHEBI:30923 biolink:ChemicalSubstance 4-hydroxy-2-oxoglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30923 CHEBI:30921 biolink:ChemicalSubstance glutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30921 chebi_ph7_3 CHEBI:30920 biolink:ChemicalSubstance 3-hydroxy-3-methylglutarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30920 CHEBI:29934 biolink:ChemicalSubstance (1s,4s)-prephenate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29934 chebi_ph7_3 CHEBI:30929 biolink:ChemicalSubstance 2,3-dihydroxybutanedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30929 chebi_ph7_3 GO:1904159 biolink:BiologicalProcess megasporocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte. go-plus.json megaspore mother cell differentiation http://purl.obolibrary.org/obo/GO_1904159 CHEBI:30928 biolink:ChemicalSubstance meso-tartrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30928 chebi_ph7_3 GO:1904158 biolink:BiologicalProcess axonemal central apparatus assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus. go-plus.json axonemal central apparatus formation http://purl.obolibrary.org/obo/GO_1904158 CHEBI:30927 biolink:ChemicalSubstance D-tartrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30927 chebi_ph7_3 GO:1904157 biolink:BiologicalProcess DN4 thymocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-. go-plus.json http://purl.obolibrary.org/obo/GO_1904157 CHEBI:30926 biolink:ChemicalSubstance 3-oxalomalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30926 GO:1904167 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904167 BSPO:0015014 biolink:OntologyClass immediately_superficial_to BSPO:0015014 go-plus.json http://purl.obolibrary.org/obo/BSPO_0015014 GO:1904166 biolink:BiologicalProcess obsolete negative regulation of cholesterol homeostasis OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol homeostasis. go-plus.json down regulation of cholesterol homeostasis|downregulation of cholesterol homeostasis|down-regulation of cholesterol homeostasis|inhibition of cholesterol homeostasis http://purl.obolibrary.org/obo/GO_1904166 GO:1904165 biolink:BiologicalProcess obsolete positive regulation of triglyceride homeostasis OBSOLETE. Any process that activates or increases the frequency, rate or extent of triglyceride homeostasis. go-plus.json up regulation of triglyceride homeostasis|up-regulation of triacylglycerol homeostasis|upregulation of triglyceride homeostasis|upregulation of triacylglycerol homeostasis|activation of triglyceride homeostasis|up-regulation of triglyceride homeostasis|up regulation of triacylglycerol homeostasis|activation of triacylglycerol homeostasis|positive regulation of triacylglycerol homeostasis http://purl.obolibrary.org/obo/GO_1904165 GO:1904164 biolink:BiologicalProcess obsolete negative regulation of triglyceride homeostasis OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride homeostasis. go-plus.json down-regulation of triacylglycerol homeostasis|negative regulation of triacylglycerol homeostasis|downregulation of triglyceride homeostasis|down regulation of triglyceride homeostasis|inhibition of triacylglycerol homeostasis|inhibition of triglyceride homeostasis|down regulation of triacylglycerol homeostasis|downregulation of triacylglycerol homeostasis|down-regulation of triglyceride homeostasis http://purl.obolibrary.org/obo/GO_1904164 GO:1904163 biolink:BiologicalProcess obsolete regulation of triglyceride homeostasis OBSOLETE. Any process that modulates the frequency, rate or extent of triglyceride homeostasis. go-plus.json regulation of triacylglycerol homeostasis http://purl.obolibrary.org/obo/GO_1904163 GO:1904162 biolink:MolecularActivity obsolete 5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair OBSOLETE. Any 5'-3' exodeoxyribonuclease activity that is involved in UV-damage excision repair. go-plus.json 5'-3' exodeoxyribonuclease activity involved in UVER|5'-3' exodeoxyribonuclease activity involved in AER|5'-3' exodeoxyribonuclease activity involved in alternative excision repair|5'-3' exodeoxyribonuclease activity involved in UVDE-dependent excision repair|5'-3' exodeoxyribonuclease activity involved in UV-damaged DNA endonuclease-dependent excision repair http://purl.obolibrary.org/obo/GO_1904162 GO:1904161 biolink:BiologicalProcess DNA synthesis involved in UV-damage excision repair Any DNA synthesis that is involved in UV-damage excision repair. go-plus.json mitotic DNA repair synthesis involved in UVDE-dependent excision repair|DNA synthesis involved in UVER|mitotic DNA repair synthesis involved in UVER|mitotic DNA repair synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UVDE-dependent excision repair|DNA synthesis during UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis involved in AER|DNA synthesis during UVER|DNA synthesis involved in alternative excision repair|mitotic DNA repair synthesis involved in UV-damage excision repair|DNA synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UV-damage excision repair|DNA synthesis involved in UVDE-dependent excision repair http://purl.obolibrary.org/obo/GO_1904161 GO:1904160 biolink:BiologicalProcess protein localization to chloroplast starch grain A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain. go-plus.json protein localisation in chloroplast starch grain|protein localization in chloroplast starch grain|protein localisation to chloroplast starch grain http://purl.obolibrary.org/obo/GO_1904160 CHEBI:30936 biolink:ChemicalSubstance L-citramalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30936 chebi_ph7_3 CHEBI:29947 biolink:ChemicalSubstance glycine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29947 chebi_ph7_3 CHEBI:30935 biolink:ChemicalSubstance 3-phosphonopyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30935 CHEBI:30934 biolink:ChemicalSubstance D-citramalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30934 chebi_ph7_3 CHEBI:30933 biolink:ChemicalSubstance 3-phosphonooxypyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30933 CHEBI:30939 biolink:ChemicalSubstance 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30939 CHEBI:30938 biolink:ChemicalSubstance 6-aminopenicillanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30938 GO:1904169 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904169 GO:1904168 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904168 GO:1904178 biolink:BiologicalProcess negative regulation of adipose tissue development Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. go-plus.json down regulation of adipose tissue development|inhibition of adipose tissue development|downregulation of adipogenesis|down regulation of adipogenesis|inhibition of adipogenesis|down-regulation of adipose tissue development|downregulation of adipose tissue development|down-regulation of adipogenesis|negative regulation of adipogenesis http://purl.obolibrary.org/obo/GO_1904178 GO:1904177 biolink:BiologicalProcess regulation of adipose tissue development Any process that modulates the frequency, rate or extent of adipose tissue development. go-plus.json regulation of adipogenesis http://purl.obolibrary.org/obo/GO_1904177 GO:1904176 biolink:CellularComponent carbon phosphorus lyase complex A protein complex which is capable of carbon phosphorus lyase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904176 GO:1904175 biolink:BiologicalProcess positive regulation of histone demethylase activity (H3-K4 specific) Any process that activates or increases the frequency, rate or extent of histone demethylase activity (H3-K4 specific). go-plus.json upregulation of histone demethylase activity (H3-K4 specific)|up regulation of histone demethylase activity (H3-K4 specific)|activation of histone demethylase activity (H3-K4 specific)|up-regulation of histone demethylase activity (H3-K4 specific) http://purl.obolibrary.org/obo/GO_1904175 GO:1904174 biolink:BiologicalProcess negative regulation of histone demethylase activity (H3-K4 specific) Any process that stops, prevents or reduces the frequency, rate or extent of histone demethylase activity (H3-K4 specific). go-plus.json down regulation of histone demethylase activity (H3-K4 specific)|downregulation of histone demethylase activity (H3-K4 specific)|down-regulation of histone demethylase activity (H3-K4 specific)|inhibition of histone demethylase activity (H3-K4 specific) http://purl.obolibrary.org/obo/GO_1904174 GO:1904173 biolink:BiologicalProcess regulation of histone demethylase activity (H3-K4 specific) Any process that modulates the frequency, rate or extent of histone demethylase activity (H3-K4 specific). go-plus.json http://purl.obolibrary.org/obo/GO_1904173 GO:1904172 biolink:BiologicalProcess positive regulation of bleb assembly Any process that activates or increases the frequency, rate or extent of bleb assembly. go-plus.json upregulation of cell blebbing|upregulation of bleb assembly|up regulation of cell blebbing|activation of cell blebbing|positive regulation of cell blebbing|up regulation of bleb assembly|activation of bleb assembly|up-regulation of cell blebbing|up-regulation of bleb assembly http://purl.obolibrary.org/obo/GO_1904172 GO:1904171 biolink:BiologicalProcess negative regulation of bleb assembly Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly. go-plus.json down regulation of cell blebbing|downregulation of cell blebbing|down regulation of bleb assembly|downregulation of bleb assembly|down-regulation of cell blebbing|negative regulation of cell blebbing|down-regulation of bleb assembly|inhibition of cell blebbing|inhibition of bleb assembly http://purl.obolibrary.org/obo/GO_1904171 GO:1904170 biolink:BiologicalProcess regulation of bleb assembly Any process that modulates the frequency, rate or extent of bleb assembly. go-plus.json regulation of cell blebbing http://purl.obolibrary.org/obo/GO_1904170 CHEBI:30903 biolink:ChemicalSubstance (-)-homoisocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30903 CHEBI:30909 biolink:ChemicalSubstance 1-alkyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30909 chebi_ph7_3 CHEBI:30907 biolink:ChemicalSubstance 4-fumarylacetoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30907 CHEBI:30904 biolink:ChemicalSubstance homoisocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30904 chebi_ph7_3 GO:1904179 biolink:BiologicalProcess positive regulation of adipose tissue development Any process that activates or increases the frequency, rate or extent of adipose tissue development. go-plus.json positive regulation of adipogenesis|upregulation of adipose tissue development|up regulation of adipogenesis|activation of adipose tissue development|up-regulation of adipose tissue development|upregulation of adipogenesis|up-regulation of adipogenesis|up regulation of adipose tissue development|activation of adipogenesis http://purl.obolibrary.org/obo/GO_1904179 GO:1904189 biolink:BiologicalProcess positive regulation of transformation of host cell by virus Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus. go-plus.json up regulation of transformation of host cell by virus|activation of viral transformation|upregulation of viral transformation of host cell|up-regulation of viral transformation|upregulation of transformation of host cell by virus|up regulation of viral transformation of host cell|activation of viral transformation of host cell|positive regulation of viral transformation|positive regulation of viral transformation of host cell|up regulation of viral transformation|activation of transformation of host cell by virus|up-regulation of transformation of host cell by virus|upregulation of viral transformation|up-regulation of viral transformation of host cell http://purl.obolibrary.org/obo/GO_1904189 GO:1904188 biolink:BiologicalProcess negative regulation of transformation of host cell by virus Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus. go-plus.json down regulation of viral transformation of host cell|downregulation of transformation of host cell by virus|downregulation of viral transformation of host cell|down-regulation of viral transformation|negative regulation of viral transformation|down regulation of transformation of host cell by virus|inhibition of transformation of host cell by virus|downregulation of viral transformation|down-regulation of viral transformation of host cell|negative regulation of viral transformation of host cell|down regulation of viral transformation|inhibition of viral transformation|inhibition of viral transformation of host cell|down-regulation of transformation of host cell by virus http://purl.obolibrary.org/obo/GO_1904188 GO:1904187 biolink:BiologicalProcess regulation of transformation of host cell by virus Any process that modulates the frequency, rate or extent of transformation of host cell by virus. go-plus.json regulation of viral transformation of host cell|regulation of viral transformation http://purl.obolibrary.org/obo/GO_1904187 GO:1904186 biolink:BiologicalProcess post-anaphase microtubule array organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array. go-plus.json post-anaphase array organization|PAA organization|post-anaphase microtubule array organisation http://purl.obolibrary.org/obo/GO_1904186 UBERON:0007198 biolink:AnatomicalEntity hermaphrodite anatomical structure An anatomical structure present only in hermaphrodites. go-plus.json hermaphrodite-specific http://purl.obolibrary.org/obo/UBERON_0007198 GO:1904185 biolink:BiologicalProcess equatorial microtubule organizing center assembly The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center. go-plus.json EMTOC assembly|EMTOC formation|equatorial microtubule organising centre assembly|equatorial microtubule organizing center formation|equatorial microtubule organising centre formation http://purl.obolibrary.org/obo/GO_1904185 GO:1904184 biolink:BiologicalProcess positive regulation of pyruvate dehydrogenase activity Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity. go-plus.json upregulation of pyruvate dehydrogenase activity|upregulation of pyruvic dehydrogenase activity|up-regulation of pyruvic acid dehydrogenase activity|up-regulation of pyruvic dehydrogenase activity|activation of pyruvic dehydrogenase activity|up regulation of pyruvate dehydrogenase activity|activation of pyruvate dehydrogenase activity|upregulation of pyruvic acid dehydrogenase activity|positive regulation of pyruvic dehydrogenase activity|up regulation of pyruvic dehydrogenase activity|up-regulation of pyruvate dehydrogenase activity|up regulation of pyruvic acid dehydrogenase activity|activation of pyruvic acid dehydrogenase activity|positive regulation of pyruvic acid dehydrogenase activity http://purl.obolibrary.org/obo/GO_1904184 UBERON:0007197 biolink:AnatomicalEntity hermaphroditic organism multicellular organism that can produce both male and female gametes. go-plus.json hermaphrodite|dioecious organism http://purl.obolibrary.org/obo/UBERON_0007197 GO:1904183 biolink:BiologicalProcess negative regulation of pyruvate dehydrogenase activity Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity. go-plus.json negative regulation of pyruvic acid dehydrogenase activity|down-regulation of pyruvic acid dehydrogenase activity|down regulation of pyruvate dehydrogenase activity|downregulation of pyruvate dehydrogenase activity|inhibition of pyruvic acid dehydrogenase activity|down-regulation of pyruvic dehydrogenase activity|down-regulation of pyruvate dehydrogenase activity|negative regulation of pyruvic dehydrogenase activity|down regulation of pyruvic acid dehydrogenase activity|inhibition of pyruvate dehydrogenase activity|downregulation of pyruvic acid dehydrogenase activity|downregulation of pyruvic dehydrogenase activity|down regulation of pyruvic dehydrogenase activity|inhibition of pyruvic dehydrogenase activity http://purl.obolibrary.org/obo/GO_1904183 UBERON:0007196 biolink:AnatomicalEntity tracheobronchial tree The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells. go-plus.json tracheobronchial system|arbor tracheobronchialis http://purl.obolibrary.org/obo/UBERON_0007196 UBERON:0007195 biolink:AnatomicalEntity stroma of bone marrow The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis. go-plus.json bone marrow stroma http://purl.obolibrary.org/obo/UBERON_0007195 GO:1904182 biolink:BiologicalProcess regulation of pyruvate dehydrogenase activity Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity. go-plus.json regulation of pyruvic acid dehydrogenase activity|regulation of pyruvic dehydrogenase activity http://purl.obolibrary.org/obo/GO_1904182 GO:1904181 biolink:BiologicalProcess positive regulation of membrane depolarization Any process that activates or increases the frequency, rate or extent of membrane depolarization. go-plus.json up regulation of membrane depolarization|activation of membrane depolarization|up-regulation of membrane depolarization|upregulation of membrane depolarization http://purl.obolibrary.org/obo/GO_1904181 GO:1904180 biolink:BiologicalProcess negative regulation of membrane depolarization Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization. go-plus.json down regulation of membrane depolarization|downregulation of membrane depolarization|down-regulation of membrane depolarization|inhibition of membrane depolarization http://purl.obolibrary.org/obo/GO_1904180 CHEBI:29918 biolink:ChemicalSubstance sulfanylium go-plus.json http://purl.obolibrary.org/obo/CHEBI_29918 CHEBI:29917 biolink:ChemicalSubstance thiol group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29917 chebi_ph7_3 CHEBI:29919 biolink:ChemicalSubstance hydrosulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29919 chebi_ph7_3 CHEBI:30913 biolink:ChemicalSubstance L-pipecolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30913 CHEBI:29924 biolink:ChemicalSubstance hydrogenselenite go-plus.json http://purl.obolibrary.org/obo/CHEBI_29924 CHEBI:30912 biolink:ChemicalSubstance 1-piperideine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30912 CHEBI:30911 biolink:ChemicalSubstance glucitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_30911 CHEBI:29920 biolink:ChemicalSubstance phosphoramidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29920 chebi_ph7_3 CHEBI:29922 biolink:ChemicalSubstance sulfo group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29922 UBERON:0007182 biolink:AnatomicalEntity muscle layer of infundibulum of uterine tube A muscle layer that is part of a uterine tube infundibulum. go-plus.json muscularis of infundibulum of uterine tube|muscle layer of infundibulum of oviduct|muscle layer of infundibulum of fallopian tube http://purl.obolibrary.org/obo/UBERON_0007182 UBERON:0007181 biolink:AnatomicalEntity serosa of infundibulum of uterine tube A serous membrane that is part of a uterine tube infundibulum. go-plus.json serosa of infundibulum of fallopian tube|serosa of infundibulum of oviduct http://purl.obolibrary.org/obo/UBERON_0007181 CHEBI:30918 biolink:ChemicalSubstance 3-dehydroshikimic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30918 CHEBI:30916 biolink:ChemicalSubstance 2-oxoglutarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30916 CHEBI:30915 biolink:ChemicalSubstance 2-oxoglutaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30915 GO:1904199 biolink:BiologicalProcess positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization. go-plus.json positive regulation of regulation of vascular smooth muscle cell membrane depolarization|upregulation of regulation of vascular smooth muscle cell membrane depolarization|up regulation of regulation of vascular smooth muscle cell membrane depolarization|activation of regulation of vascular smooth muscle cell membrane depolarization|up-regulation of regulation of vascular smooth muscle cell membrane depolarization http://purl.obolibrary.org/obo/GO_1904199 GO:1904198 biolink:BiologicalProcess negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization. go-plus.json negative regulation of regulation of vascular smooth muscle cell membrane depolarization|down regulation of regulation of vascular smooth muscle cell membrane depolarization|downregulation of regulation of vascular smooth muscle cell membrane depolarization|down-regulation of regulation of vascular smooth muscle cell membrane depolarization|inhibition of regulation of vascular smooth muscle cell membrane depolarization http://purl.obolibrary.org/obo/GO_1904198 UBERON:0007188 biolink:AnatomicalEntity mesothelium of serous pericardium A mesothelium that is part of a serous pericardium. go-plus.json pericardial mesothelium|mesothelium of pericardium|serous pericardium mesothelium http://purl.obolibrary.org/obo/UBERON_0007188 GO:1904197 biolink:BiologicalProcess positive regulation of granulosa cell proliferation Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation. go-plus.json upregulation of granulosa cell proliferation|up-regulation of granulosa cell proliferation|activation of granulosa cell proliferation|up regulation of granulosa cell proliferation http://purl.obolibrary.org/obo/GO_1904197 GO:1904196 biolink:BiologicalProcess negative regulation of granulosa cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation. go-plus.json downregulation of granulosa cell proliferation|down regulation of granulosa cell proliferation|inhibition of granulosa cell proliferation|down-regulation of granulosa cell proliferation http://purl.obolibrary.org/obo/GO_1904196 CHEBI:8707 biolink:ChemicalSubstance quetiapine go-plus.json http://purl.obolibrary.org/obo/CHEBI_8707 GO:1904195 biolink:BiologicalProcess regulation of granulosa cell proliferation Any process that modulates the frequency, rate or extent of granulosa cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_1904195 GO:1904194 biolink:BiologicalProcess positive regulation of cholangiocyte apoptotic process Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process. go-plus.json upregulation of epithelial cell of bile duct apoptotic process|up-regulation of cholangiocyte apoptotic process|upregulation of cholangiocyte apoptosis|up-regulation of epithelial cell of bile duct apoptosis|up-regulation of epithelial cell of bile duct apoptotic process|upregulation of cholangiocyte apoptotic process|activation of epithelial cell of bile duct apoptosis|activation of epithelial cell of bile duct apoptotic process|up regulation of cholangiocyte apoptosis|positive regulation of epithelial cell of bile duct apoptosis|positive regulation of cholangiocyte apoptosis|up regulation of epithelial cell of bile duct apoptosis|up regulation of cholangiocyte apoptotic process|activation of cholangiocyte apoptotic process|positive regulation of epithelial cell of bile duct apoptotic process|activation of cholangiocyte apoptosis|up regulation of epithelial cell of bile duct apoptotic process|upregulation of epithelial cell of bile duct apoptosis|up-regulation of cholangiocyte apoptosis http://purl.obolibrary.org/obo/GO_1904194 GO:1904193 biolink:BiologicalProcess negative regulation of cholangiocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process. go-plus.json inhibition of epithelial cell of bile duct apoptotic process|inhibition of epithelial cell of bile duct apoptosis|inhibition of cholangiocyte apoptosis|inhibition of cholangiocyte apoptotic process|down regulation of cholangiocyte apoptosis|downregulation of cholangiocyte apoptosis|down-regulation of epithelial cell of bile duct apoptosis|negative regulation of epithelial cell of bile duct apoptosis|down regulation of cholangiocyte apoptotic process|downregulation of cholangiocyte apoptotic process|negative regulation of epithelial cell of bile duct apoptotic process|down-regulation of epithelial cell of bile duct apoptotic process|negative regulation of cholangiocyte apoptosis|down-regulation of cholangiocyte apoptosis|downregulation of epithelial cell of bile duct apoptosis|down regulation of epithelial cell of bile duct apoptosis|downregulation of epithelial cell of bile duct apoptotic process|down-regulation of cholangiocyte apoptotic process|down regulation of epithelial cell of bile duct apoptotic process http://purl.obolibrary.org/obo/GO_1904193 GO:1904192 biolink:BiologicalProcess regulation of cholangiocyte apoptotic process Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process. go-plus.json regulation of cholangiocyte apoptosis|regulation of epithelial cell of bile duct apoptosis|regulation of epithelial cell of bile duct apoptotic process http://purl.obolibrary.org/obo/GO_1904192 GO:1904191 biolink:BiologicalProcess positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division. go-plus.json positive regulation of cyclin-dependent protein kinase activity involved in meiosis|up-regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|upregulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|up regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|activation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|positive regulation of CDK activity involved in meiotic nuclear division|stimulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division http://purl.obolibrary.org/obo/GO_1904191 GO:1904190 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904190 CHEBI:78903 biolink:ChemicalSubstance mannoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_78903 CHEBI:78902 biolink:ChemicalSubstance L-canavanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78902 chebi_ph7_3 CHEBI:78907 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78907 chebi_ph7_3 CHEBI:78904 biolink:ChemicalSubstance 4,4-dimethyl-8,14-cholestadien-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78904 chebi_ph7_3 CHEBI:78909 biolink:ChemicalSubstance 12-HPEPE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78909 CHEBI:78908 biolink:ChemicalSubstance 10(R)-HPO(6,8,12)TrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78908 CHEBI:78911 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1'D-myo-inositol-5'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78911 chebi_ph7_3 CHEBI:78918 biolink:ChemicalSubstance dotriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78918 CHEBI:78917 biolink:ChemicalSubstance triacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78917 CHEBI:78915 biolink:ChemicalSubstance triacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78915 CHEBI:78919 biolink:ChemicalSubstance dotriacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78919 CHEBI:78929 biolink:ChemicalSubstance N-hexadecanoylphosphatidylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78929 CHEBI:78920 biolink:ChemicalSubstance dotriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78920 CHEBI:78936 biolink:ChemicalSubstance hexatriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78936 CHEBI:78935 biolink:ChemicalSubstance hexatriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78935 CHEBI:78934 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-D-myo-inositol-3'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78934 chebi_ph7_3 CHEBI:78933 biolink:ChemicalSubstance tetratriacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78933 CHEBI:78939 biolink:ChemicalSubstance octatriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78939 CHEBI:78938 biolink:ChemicalSubstance octatriacontatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78938 CHEBI:78937 biolink:ChemicalSubstance hexatriacontahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78937 CHEBI:78932 biolink:ChemicalSubstance tetratriacontapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78932 CHEBI:78931 biolink:ChemicalSubstance 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1'-D-myo-inositol)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78931 chebi_ph7_3 CHEBI:78930 biolink:ChemicalSubstance 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1'-D-myo-inositol-5'-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78930 chebi_ph7_3 GO:0052568 biolink:BiologicalProcess obsolete response to symbiont phytoalexin production OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json response to symbiont phytoalexin production http://purl.obolibrary.org/obo/GO_0052568 GO:0052567 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052567 GO:0052566 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052566 GO:0052565 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052565 GO:0052569 biolink:BiologicalProcess obsolete response to defense-related symbiont nitric oxide production OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json response to defense-related symbiont nitric oxide production http://purl.obolibrary.org/obo/GO_0052569 UBERON:0007135 biolink:AnatomicalEntity neural keel An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. go-plus.json presumptive central nervous system http://purl.obolibrary.org/obo/UBERON_0007135 UBERON:0007134 biolink:AnatomicalEntity trunk ganglion Ganglion which is located in the trunk. go-plus.json trunk ganglia|body ganglion http://purl.obolibrary.org/obo/UBERON_0007134 UBERON:0007132 biolink:AnatomicalEntity head kidney Teleost head kidney consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis[ZFA,modified]. go-plus.json anterior kidney|kidney marrow http://purl.obolibrary.org/obo/UBERON_0007132 CHEBI:15368 biolink:ChemicalSubstance acrolein go-plus.json http://purl.obolibrary.org/obo/CHEBI_15368 chebi_ph7_3 CHEBI:15367 biolink:ChemicalSubstance all-trans-retinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15367 PR:000026291 biolink:Protein unmodified amino-acid residue An amino-acid residue that has not been covalently modified by chemical alteration to the side chain or backbone atoms. go-plus.json unmodified protein residue|unmodified amino acid chain residue http://purl.obolibrary.org/obo/PR_000026291 CHEBI:15369 biolink:ChemicalSubstance actinomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15369 GO:0052560 biolink:BiologicalProcess obsolete induction by organism of symbiont immune response OBSOLETE. Any process by which an organism activates the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of symbiont immune response http://purl.obolibrary.org/obo/GO_0052560 CHEBI:15364 biolink:ChemicalSubstance propynoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15364 chebi_ph7_3 CHEBI:15363 biolink:ChemicalSubstance N-acetylindoxyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_15363 chebi_ph7_3 CHEBI:15366 biolink:ChemicalSubstance acetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15366 CHEBI:15365 biolink:ChemicalSubstance acetylsalicylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15365 CHEBI:15360 biolink:ChemicalSubstance acetylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15360 chebi_ph7_3 GO:0052564 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052564 GO:0052563 biolink:BiologicalProcess obsolete negative regulation by organism of symbiont immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by organism of symbiont immune response http://purl.obolibrary.org/obo/GO_0052563 CHEBI:8798 biolink:ChemicalSubstance 4a,5-dihydroriboflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8798 chebi_ph7_3 GO:0052562 biolink:BiologicalProcess suppression by symbiont of host immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json down-regulation by symbiont of host immune response|negative regulation by symbiont of host immune response|downregulation by symbiont of host immune response|down regulation by symbiont of host immune response|inhibition by symbiont of host immune response|negative regulation by organism of immune response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052562 CHEBI:15362 biolink:ChemicalSubstance hydroxyacetone phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15362 CHEBI:15361 biolink:ChemicalSubstance pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15361 chebi_ph7_3 GO:0052561 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052561 GO:0052579 biolink:MolecularActivity (+)-pulegone reductase, (+)-isomenthone as substrate, activity Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+. MetaCyc:RXN-5164|EC:1.3.1.81 go-plus.json (+)-isomenthone:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052579 GO:0052578 biolink:MolecularActivity alpha-farnesene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate. MetaCyc:RXN-8574|RHEA:27421 go-plus.json (E,E)-alpha-farnesene synthase activity http://purl.obolibrary.org/obo/GO_0052578 GO:0052577 biolink:MolecularActivity germacrene-D synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate. MetaCyc:RXN-8562|KEGG_REACTION:R07648|EC:4.2.3.22|RHEA:12016 go-plus.json 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-Germacrene D-forming] activity http://purl.obolibrary.org/obo/GO_0052577 GO:0052576 biolink:BiologicalProcess carbohydrate storage The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. go-plus.json http://purl.obolibrary.org/obo/GO_0052576 UBERON:0007125 biolink:AnatomicalEntity pharyngeal pouch 4 A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes in amniotes). go-plus.json 4th arch branchial pouch|4th pharyngeal pouch endoderm|4th arch branchial pouch endoderm|4th branchial pouch|visceral pouch 4|fourth branchial pouch|fourth arch pharyngeal pouch|pharyngeal pouches 4|fourth pharyngeal pouch|fourth visceral pouch http://purl.obolibrary.org/obo/UBERON_0007125 UBERON:0007124 biolink:AnatomicalEntity pharyngeal pouch 3 A pharyngeal pouch that between pharyngeal arches 3 and 4. go-plus.json third pharyngeal pouch|3rd pharyngeal pouch endoderm|third arch pharyngeal pouch|3rd branchial pouch|3rd arch branchial pouch endoderm|third visceral pouch|visceral pouch 3|pharyngeal pouches 3|3rd arch branchial pouch http://purl.obolibrary.org/obo/UBERON_0007124 UBERON:0007123 biolink:AnatomicalEntity pharyngeal pouch 2 A pharyngeal puch that is between the pharyngeal arches 2 and 3. go-plus.json 2nd pharyngeal pouch endoderm|2nd branchial pouch|2nd arch branchial pouch endoderm|second pharyngeal pouch|visceral pouch 2|2nd arch pouch endoderm|pharyngeal pouches 2|second visceral pouch|second arch pharyngeal pouch|2nd arch branchial pouch http://purl.obolibrary.org/obo/UBERON_0007123 UBERON:0007122 biolink:AnatomicalEntity pharyngeal pouch 1 A pharyngeal pouch that is between pharyngeal arches 1 and 2. go-plus.json 1st arch branchial pouch|1st arch pouch endoderm|first pharyngeal pouch|visceral pouch 1|first visceral pouch|hyomandibular pouch|pharyngeal pouches 1|1st pharyngeal pouch endoderm|1st arch branchial pouch endoderm|1st branchial pouch|first arch pharyngeal pouch http://purl.obolibrary.org/obo/UBERON_0007122 CHEBI:15357 biolink:ChemicalSubstance acetylenedicarboxylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15357 chebi_ph7_3 CHEBI:15356 biolink:ChemicalSubstance cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15356 CHEBI:15358 biolink:ChemicalSubstance histone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15358 GO:0052571 biolink:BiologicalProcess obsolete response to symbiont immune response OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json response to symbiont immune response http://purl.obolibrary.org/obo/GO_0052571 CHEBI:15353 biolink:ChemicalSubstance blasticidin S go-plus.json http://purl.obolibrary.org/obo/CHEBI_15353 GO:0052570 biolink:BiologicalProcess obsolete response to defense-related symbiont reactive oxygen species production OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json response to defense-related symbiont reactive oxygen species production http://purl.obolibrary.org/obo/GO_0052570 CHEBI:15355 biolink:ChemicalSubstance acetylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15355 chebi_ph7_3 OBO:go/extensions/ro_pending#alters_location_of biolink:OntologyClass obsolete alters location of go-plus.json http://purl.obolibrary.org/obo/go/extensions/ro_pending#alters_location_of CHEBI:15354 biolink:ChemicalSubstance choline go-plus.json http://purl.obolibrary.org/obo/CHEBI_15354 chebi_ph7_3 GO:0052575 biolink:BiologicalProcess carbohydrate localization Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y. go-plus.json carbohydrate localisation http://purl.obolibrary.org/obo/GO_0052575 GO:0052574 biolink:BiologicalProcess UDP-galactose biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate. go-plus.json uridine diphosphate galactose biosynthetic process|uridine diphosphate galactose biosynthesis|UDP-D-galactopyranose biosynthesis|UDP-D-galactopyranose biosynthetic process|UDP-D-galactose biosynthetic process|UDP-D-galactose biosynthesis|UDP-galactose biosynthesis http://purl.obolibrary.org/obo/GO_0052574 UBERON:0007128 biolink:AnatomicalEntity glomeral mesenchyme Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm. go-plus.json corpuscle|glomerulus http://purl.obolibrary.org/obo/UBERON_0007128 GO:0052573 biolink:BiologicalProcess UDP-D-galactose metabolic process The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate. go-plus.json UDP-galactose metabolism|UDP-D-galactopyranose metabolic process|uridine diphosphate galactose metabolism|uridine diphosphate galactose metabolic process|UDP-D-galactopyranose metabolism|UDP-D-galactose metabolism|UDP-galactose metabolic process http://purl.obolibrary.org/obo/GO_0052573 CHEBI:15351 biolink:ChemicalSubstance acetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15351 CHEBI:15350 biolink:ChemicalSubstance acetyl dihydrogen phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15350 GO:0052572 biolink:BiologicalProcess response to host immune response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json response to immune response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052572 GO:0052589 biolink:MolecularActivity malate dehydrogenase (menaquinone) activity Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol. EC:1.1.5.4|MetaCyc:RXNI-3 go-plus.json (S)-malate:(menaquinone) oxidoreductase activity|(S)-malate:menaquinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052589 GO:0052588 biolink:MolecularActivity diacetyl reductase ((S)-acetoin forming) activity Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH. EC:1.1.1.304|RHEA:27286|KEGG_REACTION:R09078|MetaCyc:RXN-11032 go-plus.json (S)-acetoin dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052588 CHEBI:15391 biolink:ChemicalSubstance (-)-bisdechlorogeodin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15391 chebi_ph7_3 GO:0052587 biolink:MolecularActivity diacetyl reductase ((R)-acetoin forming) activity Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH. RHEA:22900|KEGG_REACTION:R02855|EC:1.1.1.303|MetaCyc:RXN-11036 go-plus.json (R)-acetoin dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052587 CHEBI:15390 biolink:ChemicalSubstance (+)-bisdechlorogeodin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15390 chebi_ph7_3 CHEBI:29998 biolink:ChemicalSubstance D-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29998 chebi_ph7_3 CHEBI:30985 biolink:ChemicalSubstance 4,4'-bipyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30985 chebi_ph7_3 CHEBI:30984 biolink:ChemicalSubstance evernitrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_30984 chebi_ph7_3 CHEBI:29999 biolink:ChemicalSubstance L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29999 chebi_ph7_3 CHEBI:29994 biolink:ChemicalSubstance D-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29994 NCBITaxon:27592 biolink:OrganismalEntity Bovinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_27592 CHEBI:29993 biolink:ChemicalSubstance L-aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29993 CHEBI:29995 biolink:ChemicalSubstance aspartate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29995 CHEBI:29990 biolink:ChemicalSubstance D-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29990 chebi_ph7_3 CHEBI:29991 biolink:ChemicalSubstance L-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29991 chebi_ph7_3 GO:1904101 biolink:BiologicalProcess response to acadesine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904101 CHEBI:39317 biolink:ChemicalSubstance growth regulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_39317 GO:1904100 biolink:BiologicalProcess positive regulation of protein O-linked glycosylation Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation. go-plus.json up regulation of protein amino acid O-linked glycosylation|upregulation of protein O-linked glycosylation|positive regulation of protein amino acid O-linked glycosylation|activation of protein amino acid O-linked glycosylation|up-regulation of protein O-linked glycosylation|activation of protein O-linked glycosylation|up-regulation of protein amino acid O-linked glycosylation|upregulation of protein amino acid O-linked glycosylation|up regulation of protein O-linked glycosylation http://purl.obolibrary.org/obo/GO_1904100 CHEBI:15389 biolink:ChemicalSubstance (-)-trans-carveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15389 chebi_ph7_3 GO:0052582 biolink:MolecularActivity (+)-menthofuran synthase activity Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+). RHEA:25658|KEGG_REACTION:R08923|MetaCyc:1.14.13.104-RXN|EC:1.14.14.143 go-plus.json cytochrome P450 menthofuran synthase activity|(+)-MFS activity|(+)-pulegone 9-hydroxylase activity|(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity|menthofuran synthase activity http://purl.obolibrary.org/obo/GO_0052582 CHEBI:15386 biolink:ChemicalSubstance (3S,4R)-3,4-dihydrophenanthrene-3,4-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15386 chebi_ph7_3 GO:0052581 biolink:MolecularActivity (-)-isopiperitenone reductase activity Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+). RHEA:25649|KEGG_REACTION:R06417|MetaCyc:RXN-5161|EC:1.3.1.82 go-plus.json (+)-cis-isopulegone:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052581 CHEBI:15385 biolink:ChemicalSubstance (+)-delta-cadinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15385 chebi_ph7_3 GO:0052580 biolink:MolecularActivity (+)-pulegone reductase, (-)-menthone as substrate, activity Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+. EC:1.3.1.81|MetaCyc:RXN-5164 go-plus.json (-)-menthone:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052580 CHEBI:15388 biolink:ChemicalSubstance (+)-trans-carveol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15388 chebi_ph7_3 UBERON:0007119 biolink:AnatomicalEntity neck of femur The femur neck or neck of the femur is a flattened pyramidal process of bone, connecting the femoral head with the femoral shaft, and forming with the latter a wide angle opening medialward. go-plus.json neck of the femur|femur neck|femoral neck|collum femoris http://purl.obolibrary.org/obo/UBERON_0007119 CHEBI:15387 biolink:ChemicalSubstance (+)-cis-sabinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_15387 chebi_ph7_3 GO:0052586 biolink:MolecularActivity oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound. EC:1.7.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0052586 CHEBI:15382 biolink:ChemicalSubstance (4R)-limonene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15382 chebi_ph7_3 GO:0052585 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound. EC:1.4.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0052585 GO:0052584 biolink:MolecularActivity obsolete oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.22.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0052584 CHEBI:15384 biolink:ChemicalSubstance limonene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15384 chebi_ph7_3 GO:0052583 biolink:MolecularActivity obsolete oxidoreductase activity, acting on halogen in donors OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. EC:1.22.-.- go-plus.json http://purl.obolibrary.org/obo/GO_0052583 CHEBI:15383 biolink:ChemicalSubstance (4S)-limonene go-plus.json http://purl.obolibrary.org/obo/CHEBI_15383 chebi_ph7_3 GO:0052599 biolink:MolecularActivity methylputrescine oxidase activity Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+. MetaCyc:RXN-8244|EC:1.4.3.22|KEGG_REACTION:R05334 go-plus.json N-methylputrescine:oxygen oxidoreductase (deaminating) activity http://purl.obolibrary.org/obo/GO_0052599 CHEBI:15380 biolink:ChemicalSubstance succinyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15380 GO:0052598 biolink:MolecularActivity histamine oxidase activity Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+. MetaCyc:RXN-9600|RHEA:25625|EC:1.4.3.22|Reactome:R-HSA-5696131|KEGG_REACTION:R02150 go-plus.json 1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity|histamine:oxygen oxidoreductase (deaminating) activity|1H-Imidazole-4-ethanamine oxidase activity http://purl.obolibrary.org/obo/GO_0052598 GO:1904109 biolink:BiologicalProcess positive regulation of cholesterol import Any process that activates or increases the frequency, rate or extent of cholesterol import. go-plus.json activation of cholesterol uptake|up regulation of cholesterol import|positive regulation of cholesterol uptake|up regulation of cholesterol uptake|upregulation of cholesterol import|upregulation of cholesterol uptake|up-regulation of cholesterol import|activation of cholesterol import|up-regulation of cholesterol uptake http://purl.obolibrary.org/obo/GO_1904109 GO:1904108 biolink:BiologicalProcess protein localization to ciliary inversin compartment A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment. go-plus.json protein localization in ciliary inversin compartment|protein localisation to ciliary inversin compartment|protein localisation in ciliary inversin compartment http://purl.obolibrary.org/obo/GO_1904108 GO:1904107 biolink:BiologicalProcess protein localization to microvillus membrane A process in which a protein is transported to, or maintained in, a location within a microvillus membrane. go-plus.json protein localisation in microvillus membrane|protein localization in microvillus membrane|protein localisation to microvillus membrane http://purl.obolibrary.org/obo/GO_1904107 GO:1904106 biolink:BiologicalProcess protein localization to microvillus A process in which a protein is transported to, or maintained in, a location within a microvillus. go-plus.json protein localisation to microvillus|protein localization in microvillus|protein localisation in microvillus http://purl.obolibrary.org/obo/GO_1904106 GO:1904105 biolink:BiologicalProcess positive regulation of convergent extension involved in gastrulation Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation. go-plus.json up regulation of convergent extension involved in gastrulation|activation of convergent extension involved in gastrulation|up-regulation of convergent extension involved in gastrulation|upregulation of convergent extension involved in gastrulation http://purl.obolibrary.org/obo/GO_1904105 GO:1904104 biolink:BiologicalProcess negative regulation of convergent extension involved in gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation. go-plus.json down regulation of convergent extension involved in gastrulation|downregulation of convergent extension involved in gastrulation|down-regulation of convergent extension involved in gastrulation|inhibition of convergent extension involved in gastrulation http://purl.obolibrary.org/obo/GO_1904104 GO:1904103 biolink:BiologicalProcess regulation of convergent extension involved in gastrulation Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_1904103 GO:1904102 biolink:BiologicalProcess cellular response to acadesine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904102 GO:1904112 biolink:BiologicalProcess obsolete positive regulation of plus-end directed microfilament motor activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of plus-end directed microfilament motor activity. go-plus.json up regulation of barbed-end directed actin-filament motor activity|upregulation of plus-end directed actin-filament motor activity|activation of barbed-end directed actin-filament motor activity|positive regulation of barbed-end directed actin-filament motor activity|up regulation of plus-end directed actin filament motor activity|positive regulation of plus-end directed actin filament motor activity|up regulation of plus-end directed microfilament motor activity|activation of plus-end directed actin filament motor activity|up regulation of plus-end directed actin-filament motor activity|up-regulation of barbed-end directed actin-filament motor activity|positive regulation of plus-end directed actin-filament motor activity|activation of plus-end directed actin-filament motor activity|up-regulation of plus-end directed actin filament motor activity|upregulation of plus-end directed microfilament motor activity|upregulation of barbed-end directed actin-filament motor activity|up-regulation of plus-end directed actin-filament motor activity|upregulation of plus-end directed actin filament motor activity|up-regulation of plus-end directed microfilament motor activity|activation of plus-end directed microfilament motor activity http://purl.obolibrary.org/obo/GO_1904112 GO:1904111 biolink:BiologicalProcess obsolete negative regulation of plus-end directed microfilament motor activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of plus-end directed microfilament motor activity. go-plus.json downregulation of plus-end directed actin filament motor activity|down-regulation of plus-end directed microfilament motor activity|down regulation of plus-end directed actin-filament motor activity|down-regulation of barbed-end directed actin-filament motor activity|negative regulation of barbed-end directed actin-filament motor activity|down-regulation of plus-end directed actin filament motor activity|downregulation of plus-end directed actin-filament motor activity|negative regulation of plus-end directed actin filament motor activity|inhibition of barbed-end directed actin-filament motor activity|downregulation of plus-end directed microfilament motor activity|down regulation of plus-end directed microfilament motor activity|negative regulation of plus-end directed actin-filament motor activity|inhibition of plus-end directed microfilament motor activity|down-regulation of plus-end directed actin-filament motor activity|inhibition of plus-end directed actin filament motor activity|inhibition of plus-end directed actin-filament motor activity|down regulation of barbed-end directed actin-filament motor activity|down regulation of plus-end directed actin filament motor activity|downregulation of barbed-end directed actin-filament motor activity http://purl.obolibrary.org/obo/GO_1904111 GO:1904110 biolink:BiologicalProcess obsolete regulation of plus-end directed microfilament motor activity OBSOLETE. Any process that modulates the frequency, rate or extent of plus-end directed microfilament motor activity. go-plus.json regulation of plus-end directed actin-filament motor activity|regulation of barbed-end directed actin-filament motor activity|regulation of plus-end directed actin filament motor activity http://purl.obolibrary.org/obo/GO_1904110 UBERON:0007100 biolink:AnatomicalEntity primary circulatory organ A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. go-plus.json adult heart|dorsal tube|heart http://purl.obolibrary.org/obo/UBERON_0007100 CHEBI:15379 biolink:ChemicalSubstance dioxygen go-plus.json http://purl.obolibrary.org/obo/CHEBI_15379 chebi_ph7_3 CHEBI:15378 biolink:ChemicalSubstance hydron go-plus.json http://purl.obolibrary.org/obo/CHEBI_15378 chebi_ph7_3 CHEBI:40303 biolink:ChemicalSubstance lovastatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_40303 chebi_ph7_3 GO:0052593 biolink:MolecularActivity tryptamine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+. MetaCyc:RXN-1401|EC:1.4.3.21|KEGG_REACTION:R02173 go-plus.json http://purl.obolibrary.org/obo/GO_0052593 CHEBI:15375 biolink:ChemicalSubstance D-erythro-7,8-dihydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15375 chebi_ph7_3 CHEBI:15374 biolink:ChemicalSubstance 4a-hydroxytetrahydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15374 chebi_ph7_3 GO:0052592 biolink:MolecularActivity oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. EC:1.17.7.- go-plus.json oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor http://purl.obolibrary.org/obo/GO_0052592 GO:0052591 biolink:MolecularActivity sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8. MetaCyc:GLYC3PDEHYDROG-RXN|RHEA:28751|EC:1.1.5.3 go-plus.json http://purl.obolibrary.org/obo/GO_0052591 CHEBI:15377 biolink:ChemicalSubstance water go-plus.json http://purl.obolibrary.org/obo/CHEBI_15377 chebi_ph7_3 GO:0052590 biolink:MolecularActivity sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol. MetaCyc:RXN0-5258|EC:1.1.5.3 go-plus.json http://purl.obolibrary.org/obo/GO_0052590 GO:0052597 biolink:MolecularActivity diamine oxidase activity Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide. MetaCyc:RXN-9599|EC:1.4.3.22 go-plus.json diamine:oxygen oxidoreductase (deaminating) activity http://purl.obolibrary.org/obo/GO_0052597 CHEBI:15371 biolink:ChemicalSubstance 3-oxopristanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15371 GO:0052596 biolink:MolecularActivity phenethylamine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+. MetaCyc:AMINEPHEN-RXN|KEGG_REACTION:R02613|EC:1.4.3.21|RHEA:25265 go-plus.json http://purl.obolibrary.org/obo/GO_0052596 UBERON:0007106 biolink:AnatomicalEntity chorionic villus One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta. go-plus.json villous chorion|embryonic placenta|placental villus|villous of placenta|chorionic villus|embryonic part of placenta|fetal placenta|chorionic villous|placental villous|chorionic villi|fetal part of placenta|placental villi http://purl.obolibrary.org/obo/UBERON_0007106 CHEBI:15373 biolink:ChemicalSubstance biopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15373 chebi_ph7_3 GO:0052595 biolink:MolecularActivity aliphatic-amine oxidase activity Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+. EC:1.4.3.21|RHEA:16153|MetaCyc:AMINEOXID-RXN go-plus.json aliphatic-amine:oxygen oxidoreductase(deaminating) activity http://purl.obolibrary.org/obo/GO_0052595 GO:0052594 biolink:MolecularActivity aminoacetone:oxygen oxidoreductase(deaminating) activity Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+. KEGG_REACTION:R02529|MetaCyc:AMACETOXID-RXN|EC:1.4.3.21|RHEA:28186 go-plus.json http://purl.obolibrary.org/obo/GO_0052594 CHEBI:15372 biolink:ChemicalSubstance 5,6,7,8-tetrahydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15372 chebi_ph7_3 CHEBI:29979 biolink:ChemicalSubstance L-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29979 chebi_ph7_3 CHEBI:30968 biolink:ChemicalSubstance azetidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30968 CHEBI:29976 biolink:ChemicalSubstance D-tyrosine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29976 UBERON:0007172 biolink:AnatomicalEntity angle of scapula go-plus.json scapular angle http://purl.obolibrary.org/obo/UBERON_0007172 CHEBI:29972 biolink:ChemicalSubstance L-glutamic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29972 GO:1904119 biolink:BiologicalProcess negative regulation of otic vesicle morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis. go-plus.json inhibition of otic vesicle morphogenesis|down-regulation of otic vesicle morphogenesis|downregulation of otic vesicle morphogenesis|down regulation of otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_1904119 UBERON:0007171 biolink:AnatomicalEntity border of scapula go-plus.json scapular border http://purl.obolibrary.org/obo/UBERON_0007171 GO:1904118 biolink:BiologicalProcess regulation of otic vesicle morphogenesis Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904118 CHEBI:29974 biolink:ChemicalSubstance D-glutamate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29974 GO:1904117 biolink:BiologicalProcess cellular response to vasopressin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904117 CHEBI:29973 biolink:ChemicalSubstance L-glutamate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29973 chebi_ph7_3 GO:1904116 biolink:BiologicalProcess response to vasopressin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904116 GO:1904115 biolink:CellularComponent axon cytoplasm Any cytoplasm that is part of a axon. go-plus.json axoplasm http://purl.obolibrary.org/obo/GO_1904115 GO:1904114 biolink:BiologicalProcess positive regulation of muscle filament sliding Any process that activates or increases the frequency, rate or extent of muscle filament sliding. go-plus.json up regulation of muscle filament sliding|activation of muscle filament sliding|up-regulation of muscle filament sliding|upregulation of muscle filament sliding http://purl.obolibrary.org/obo/GO_1904114 CHEBI:29970 biolink:ChemicalSubstance D-lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29970 GO:1904113 biolink:BiologicalProcess negative regulation of muscle filament sliding Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding. go-plus.json down regulation of muscle filament sliding|downregulation of muscle filament sliding|down-regulation of muscle filament sliding|inhibition of muscle filament sliding http://purl.obolibrary.org/obo/GO_1904113 GO:1904123 biolink:BiologicalProcess positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation. go-plus.json up-regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|upregulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|up regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|activation of fatty acid beta-oxidation by serotonin receptor signaling pathway|stimulation of fatty acid beta-oxidation by serotonin receptor signaling pathway http://purl.obolibrary.org/obo/GO_1904123 GO:1904122 biolink:BiologicalProcess positive regulation of fatty acid beta-oxidation by octopamine signaling pathway An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation. go-plus.json up-regulation of fatty acid beta-oxidation by octopamine signaling pathway|upregulation of fatty acid beta-oxidation by octopamine signaling pathway|up regulation of fatty acid beta-oxidation by octopamine signaling pathway|activation of fatty acid beta-oxidation by octopamine signaling pathway|stimulation of fatty acid beta-oxidation by octopamine signaling pathway http://purl.obolibrary.org/obo/GO_1904122 GO:1904121 biolink:MolecularActivity phosphatidylethanolamine transfer activity Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. go-plus.json intermembrane phosphatidylethanolamine transfer activity|phosphatidylethanolamine carrier activity|phosphatidylethanolamine transporter activity http://purl.obolibrary.org/obo/GO_1904121 GO:1904120 biolink:BiologicalProcess positive regulation of otic vesicle morphogenesis Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis. go-plus.json up regulation of otic vesicle morphogenesis|upregulation of otic vesicle morphogenesis|up-regulation of otic vesicle morphogenesis|activation of otic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_1904120 UBERON:0007177 biolink:AnatomicalEntity lamina propria of mucosa of colon A lamina propria that is part of a colonic mucosa. go-plus.json lamina propria of colonic mucosa|colonic lamina propria|lamina propria mucosae of colon|lamina propria of colonic mucous membrane http://purl.obolibrary.org/obo/UBERON_0007177 UBERON:0007175 biolink:AnatomicalEntity inferior angle of scapula An angle of the scapula formed by the union of the vertebral and axillary borders; its dorsal surface affords attachment to the Teres major and frequently to a few fibers of the Latissimus dorsi.[WP,unvetted] go-plus.json angulus inferior (scapula)|angulus inferior scapulae http://purl.obolibrary.org/obo/UBERON_0007175 UBERON:0007174 biolink:AnatomicalEntity medial border of scapula The medial border of the scapula (vertebral border, medial margin) is the longest of the three borders, and extends from the medial to the inferior angle. It is arched, intermediate in thickness between the superior and the axillary borders, and the portion of it above the spine forms an obtuse angle with the part below. This border presents an anterior and a posterior lip, and an intermediate narrow area. The anterior lip affords attachment to the Serratus anterior; the posterior lip, to the Supraspinatus above the spine, the Infraspinatus below; the area between the two lips, to the Levator scapulC& above the triangular surface at the commencement of the spine, to the Rhomboideus minor on the edge of that surface, and to the Rhomboideus major below it; this last is attached by means of a fibrous arch, connected above to the lower part of the triangular surface at the base of the spine, and below to the lower part of the border. go-plus.json vertebral border|medial part of scapula|margo medialis (scapula)|vertebral border of the scapula|margo medialis scapulae|medial border of the scapula|medial margin of the scapula|vertebral border of scapula http://purl.obolibrary.org/obo/UBERON_0007174 UBERON:0007173 biolink:AnatomicalEntity lateral border of scapula The lateral border (or axillary border, or margin) is the thickest of the three borders of the scapula. It begins above at the lower margin of the glenoid cavity, and inclines obliquely downward and backward to the inferior angle. Immediately below the glenoid cavity is a rough impression, the infraglenoid tuberosity, about 2.5 cm. in length, which gives origin to the long head of the Triceps brachii; in front of this is a longitudinal groove, which extends as far as the lower third of this border, and affords origin to part of the Subscapularis. The inferior third is thin and sharp, and serves for the attachment of a few fibers of the Teres major behind, and of the Subscapularis in front. go-plus.json lateral part of scapula|margo lateralis scapulae|margo lateralis (scapula)|lateral border of scapula|axillary border of scapula http://purl.obolibrary.org/obo/UBERON_0007173 CHEBI:30960 biolink:ChemicalSubstance 5-pyridoxate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30960 chebi_ph7_3 CHEBI:29987 biolink:ChemicalSubstance glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29987 CHEBI:29986 biolink:ChemicalSubstance D-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29986 chebi_ph7_3 CHEBI:29989 biolink:ChemicalSubstance D-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29989 CHEBI:29988 biolink:ChemicalSubstance L-glutamate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29988 CHEBI:29982 biolink:ChemicalSubstance L-histidinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29982 GO:1904129 biolink:BiologicalProcess positive regulation of convergent extension involved in somitogenesis Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis. go-plus.json up regulation of convergent extension involved in somitogenesis|upregulation of convergent extension involved in somitogenesis|up-regulation of convergent extension involved in somitogenesis|activation of convergent extension involved in somitogenesis http://purl.obolibrary.org/obo/GO_1904129 CHEBI:29985 biolink:ChemicalSubstance L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29985 chebi_ph7_3 GO:1904128 biolink:BiologicalProcess negative regulation of convergent extension involved in somitogenesis Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis. go-plus.json downregulation of convergent extension involved in somitogenesis|down regulation of convergent extension involved in somitogenesis|inhibition of convergent extension involved in somitogenesis|down-regulation of convergent extension involved in somitogenesis http://purl.obolibrary.org/obo/GO_1904128 CHEBI:29984 biolink:ChemicalSubstance D-methionine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29984 chebi_ph7_3 GO:1904127 biolink:BiologicalProcess regulation of convergent extension involved in somitogenesis Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904127 GO:1904126 biolink:BiologicalProcess convergent extension involved in notochord morphogenesis Any convergent extension that is involved in notochord morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904126 CHEBI:29981 biolink:ChemicalSubstance D-histidinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29981 GO:1904125 biolink:BiologicalProcess convergent extension involved in rhombomere morphogenesis Any convergent extension that is involved in rhombomere morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904125 GO:1904124 biolink:BiologicalProcess microglial cell migration The orderly movement of a microglial cell from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_1904124 CHEBI:29980 biolink:ChemicalSubstance D-histidine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29980 GO:1904134 biolink:BiologicalProcess negative regulation of convergent extension involved in rhombomere morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis. go-plus.json down regulation of convergent extension involved in rhombomere morphogenesis|downregulation of convergent extension involved in rhombomere morphogenesis|down-regulation of convergent extension involved in rhombomere morphogenesis|inhibition of convergent extension involved in rhombomere morphogenesis http://purl.obolibrary.org/obo/GO_1904134 CHEBI:39306 biolink:ChemicalSubstance pyrimidodiazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39306 GO:1904133 biolink:BiologicalProcess regulation of convergent extension involved in rhombomere morphogenesis Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904133 CHEBI:39305 biolink:ChemicalSubstance imidazodiazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39305 GO:1904132 biolink:BiologicalProcess positive regulation of convergent extension involved in neural plate elongation Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation. go-plus.json up regulation of convergent extension involved in neural plate elongation|upregulation of convergent extension involved in neural plate elongation|up-regulation of convergent extension involved in neural plate elongation|activation of convergent extension involved in neural plate elongation http://purl.obolibrary.org/obo/GO_1904132 CHEBI:39304 biolink:ChemicalSubstance coformycins go-plus.json http://purl.obolibrary.org/obo/CHEBI_39304 GO:1904131 biolink:BiologicalProcess negative regulation of convergent extension involved in neural plate elongation Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation. go-plus.json down-regulation of convergent extension involved in neural plate elongation|downregulation of convergent extension involved in neural plate elongation|down regulation of convergent extension involved in neural plate elongation|inhibition of convergent extension involved in neural plate elongation http://purl.obolibrary.org/obo/GO_1904131 CHEBI:15318 biolink:ChemicalSubstance xanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15318 GO:1904130 biolink:BiologicalProcess regulation of convergent extension involved in neural plate elongation Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation. go-plus.json http://purl.obolibrary.org/obo/GO_1904130 CHEBI:39308 biolink:ChemicalSubstance 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39308 CHEBI:29958 biolink:ChemicalSubstance L-aspartic acid residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29958 CHEBI:29959 biolink:ChemicalSubstance quinolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29959 chebi_ph7_3 CHEBI:30944 biolink:ChemicalSubstance ascarylose go-plus.json http://purl.obolibrary.org/obo/CHEBI_30944 CHEBI:30943 biolink:ChemicalSubstance tyvelose go-plus.json http://purl.obolibrary.org/obo/CHEBI_30943 chebi_ph7_3 CHEBI:29953 biolink:ChemicalSubstance D-arginine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29953 CHEBI:29950 biolink:ChemicalSubstance L-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29950 chebi_ph7_3 CHEBI:29952 biolink:ChemicalSubstance L-arginine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29952 GO:1904139 biolink:BiologicalProcess regulation of microglial cell migration Any process that modulates the frequency, rate or extent of microglial cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_1904139 CHEBI:29951 biolink:ChemicalSubstance D-cysteine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29951 GO:1904138 biolink:BiologicalProcess positive regulation of convergent extension involved in notochord morphogenesis Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis. go-plus.json up regulation of convergent extension involved in notochord morphogenesis|upregulation of convergent extension involved in notochord morphogenesis|up-regulation of convergent extension involved in notochord morphogenesis|activation of convergent extension involved in notochord morphogenesis http://purl.obolibrary.org/obo/GO_1904138 GO:1904137 biolink:BiologicalProcess negative regulation of convergent extension involved in notochord morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis. go-plus.json down-regulation of convergent extension involved in notochord morphogenesis|downregulation of convergent extension involved in notochord morphogenesis|down regulation of convergent extension involved in notochord morphogenesis|inhibition of convergent extension involved in notochord morphogenesis http://purl.obolibrary.org/obo/GO_1904137 GO:1904136 biolink:BiologicalProcess regulation of convergent extension involved in notochord morphogenesis Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904136 GO:1904135 biolink:BiologicalProcess positive regulation of convergent extension involved in rhombomere morphogenesis Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis. go-plus.json upregulation of convergent extension involved in rhombomere morphogenesis|up regulation of convergent extension involved in rhombomere morphogenesis|activation of convergent extension involved in rhombomere morphogenesis|up-regulation of convergent extension involved in rhombomere morphogenesis http://purl.obolibrary.org/obo/GO_1904135 UBERON:0007158 biolink:AnatomicalEntity lumen of anal canal An anatomical cavity that surrounded_by a anal canal. go-plus.json anal canal lumen http://purl.obolibrary.org/obo/UBERON_0007158 GO:1904145 biolink:BiologicalProcess negative regulation of meiotic cell cycle process involved in oocyte maturation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. go-plus.json downregulation of meiotic cell cycle process involved in oocyte maturation|down regulation of meiotic cell cycle process involved in oocyte maturation|inhibition of meiotic cell cycle process involved in oocyte maturation|down-regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1904145 GO:1904144 biolink:CellularComponent phosphatidylinositol phosphate phosphatase complex A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity. go-plus.json prostatic acid phosphatase complex http://purl.obolibrary.org/obo/GO_1904144 CHEBI:15349 biolink:ChemicalSubstance acetone oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_15349 chebi_ph7_3 GO:1904143 biolink:BiologicalProcess positive regulation of carotenoid biosynthetic process Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process. go-plus.json upregulation of carotenoid anabolism|up regulation of carotenoid biosynthetic process|up regulation of carotenoid biosynthesis|activation of carotenoid biosynthesis|activation of carotenoid biosynthetic process|upregulation of carotenoid synthesis|positive regulation of carotenoid biosynthesis|upregulation of carotenoid formation|up-regulation of carotenoid anabolism|activation of carotenoid anabolism|up-regulation of carotenoid synthesis|activation of carotenoid synthesis|up-regulation of carotenoid biosynthetic process|up-regulation of carotenoid biosynthesis|up-regulation of carotenoid formation|activation of carotenoid formation|positive regulation of carotenoid anabolism|up regulation of carotenoid anabolism|upregulation of carotenoid biosynthesis|upregulation of carotenoid biosynthetic process|positive regulation of carotenoid synthesis|up regulation of carotenoid synthesis|positive regulation of carotenoid formation|up regulation of carotenoid formation http://purl.obolibrary.org/obo/GO_1904143 GO:1904142 biolink:BiologicalProcess negative regulation of carotenoid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process. go-plus.json down regulation of carotenoid synthesis|inhibition of carotenoid synthesis|down regulation of carotenoid formation|inhibition of carotenoid formation|negative regulation of carotenoid biosynthesis|down-regulation of carotenoid biosynthesis|down-regulation of carotenoid biosynthetic process|inhibition of carotenoid biosynthetic process|inhibition of carotenoid biosynthesis|down-regulation of carotenoid anabolism|negative regulation of carotenoid anabolism|down-regulation of carotenoid synthesis|negative regulation of carotenoid synthesis|down-regulation of carotenoid formation|negative regulation of carotenoid formation|downregulation of carotenoid anabolism|down regulation of carotenoid biosynthetic process|down regulation of carotenoid biosynthesis|down regulation of carotenoid anabolism|downregulation of carotenoid synthesis|downregulation of carotenoid biosynthesis|inhibition of carotenoid anabolism|downregulation of carotenoid biosynthetic process|downregulation of carotenoid formation http://purl.obolibrary.org/obo/GO_1904142 GO:1904141 biolink:BiologicalProcess positive regulation of microglial cell migration Any process that activates or increases the frequency, rate or extent of microglial cell migration. go-plus.json up regulation of microglial cell migration|activation of microglial cell migration|up-regulation of microglial cell migration|upregulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1904141 CHEBI:15346 biolink:ChemicalSubstance coenzyme A go-plus.json http://purl.obolibrary.org/obo/CHEBI_15346 GO:1904140 biolink:BiologicalProcess negative regulation of microglial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration. go-plus.json down-regulation of microglial cell migration|inhibition of microglial cell migration|down regulation of microglial cell migration|downregulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1904140 CHEBI:15345 biolink:ChemicalSubstance acetoacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_15345 CHEBI:15348 biolink:ChemicalSubstance 2-hydroxy-2-methylpropanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_15348 chebi_ph7_3 CHEBI:15347 biolink:ChemicalSubstance acetone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15347 chebi_ph7_3 UBERON:0007151 biolink:AnatomicalEntity mitral valve leaflet A valve leafleft that is part of a mitral valve. go-plus.json mitral valve leaflets|leaflet of mitral valve|mitral valvular leaflet|mitral valve leaflet http://purl.obolibrary.org/obo/UBERON_0007151 CHEBI:15342 biolink:ChemicalSubstance acenaphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15342 chebi_ph7_3 CHEBI:15341 biolink:ChemicalSubstance beta-D-glucosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15341 CHEBI:15344 biolink:ChemicalSubstance acetoacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_15344 CHEBI:15343 biolink:ChemicalSubstance acetaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_15343 chebi_ph7_3 UBERON:0007159 biolink:AnatomicalEntity lumen of colon An anatomical cavity that surrounded_by a colon. go-plus.json colonic lumen|colon lumen http://purl.obolibrary.org/obo/UBERON_0007159 CHEBI:29969 biolink:ChemicalSubstance L-lysinium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29969 chebi_ph7_3 CHEBI:29968 biolink:ChemicalSubstance D-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29968 CHEBI:29965 biolink:ChemicalSubstance L-argininium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29965 chebi_ph7_3 CHEBI:29964 biolink:ChemicalSubstance L-cysteinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29964 CHEBI:29967 biolink:ChemicalSubstance L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29967 CHEBI:29966 biolink:ChemicalSubstance D-argininium residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29966 CHEBI:29961 biolink:ChemicalSubstance L-aspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29961 chebi_ph7_3 CHEBI:29963 biolink:ChemicalSubstance D-cysteinate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29963 CHEBI:29962 biolink:ChemicalSubstance D-aspartate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_29962 GO:1904149 biolink:BiologicalProcess regulation of microglial cell mediated cytotoxicity Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity. go-plus.json http://purl.obolibrary.org/obo/GO_1904149 GO:1904148 biolink:BiologicalProcess cellular response to nonylphenol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904148 GO:1904147 biolink:BiologicalProcess response to nonylphenol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904147 GO:1904146 biolink:BiologicalProcess positive regulation of meiotic cell cycle process involved in oocyte maturation Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. go-plus.json up regulation of meiotic cell cycle process involved in oocyte maturation|upregulation of meiotic cell cycle process involved in oocyte maturation|up-regulation of meiotic cell cycle process involved in oocyte maturation|activation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1904146 CHEBI:30959 biolink:ChemicalSubstance 4-pyridoxate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30959 chebi_ph7_3 GO:1904156 biolink:BiologicalProcess DN3 thymocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+. go-plus.json http://purl.obolibrary.org/obo/GO_1904156 UBERON:0007147 biolink:AnatomicalEntity lumen of midgut An anatomical cavity that surrounded_by a midgut. go-plus.json midgut lumen http://purl.obolibrary.org/obo/UBERON_0007147 CHEBI:15339 biolink:ChemicalSubstance acceptor go-plus.json http://purl.obolibrary.org/obo/CHEBI_15339 GO:1904155 biolink:BiologicalProcess DN2 thymocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-. go-plus.json http://purl.obolibrary.org/obo/GO_1904155 GO:1904154 biolink:BiologicalProcess positive regulation of retrograde protein transport, ER to cytosol Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol. go-plus.json up regulation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of retrograde protein transport, ER to cytosol|upregulation of protein dislocation from ER|activation of retrograde protein transport, ER to cytosol|positive regulation of protein retrotranslocation from ER|upregulation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of protein dislocation from ER|up-regulation of retrograde protein transport, ER to cytosol|positive regulation of protein dislocation from ER|activation of protein dislocation from ER|up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|activation of retrograde protein transport, endoplasmic reticulum to cytosol|upregulation of retrograde protein transport, ER to cytosol|up-regulation of protein dislocation from ER|up-regulation of protein retrotranslocation from ER|positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol http://purl.obolibrary.org/obo/GO_1904154 GO:1904153 biolink:BiologicalProcess negative regulation of retrograde protein transport, ER to cytosol Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol. go-plus.json negative regulation of protein retrotranslocation from ER|downregulation of retrograde protein transport, endoplasmic reticulum to cytosol|down regulation of protein dislocation from ER|down-regulation of retrograde protein transport, ER to cytosol|down regulation of retrograde protein transport, endoplasmic reticulum to cytosol|inhibition of retrograde protein transport, endoplasmic reticulum to cytosol|downregulation of protein dislocation from ER|inhibition of retrograde protein transport, ER to cytosol|down-regulation of protein dislocation from ER|negative regulation of protein dislocation from ER|inhibition of protein dislocation from ER|down regulation of retrograde protein transport, ER to cytosol|down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol|downregulation of retrograde protein transport, ER to cytosol http://purl.obolibrary.org/obo/GO_1904153 UBERON:0007144 biolink:AnatomicalEntity embryonic post-anal tail An embryonic structure that will either develop into a post-anal tail or recede into a vestigial remnant of the tail. go-plus.json embryonic tail|tail of embryo|embryo tail http://purl.obolibrary.org/obo/UBERON_0007144 GO:1904152 biolink:BiologicalProcess regulation of retrograde protein transport, ER to cytosol Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol. go-plus.json regulation of retrograde protein transport, endoplasmic reticulum to cytosol|regulation of protein dislocation from ER|regulation of protein retrotranslocation from ER http://purl.obolibrary.org/obo/GO_1904152 UBERON:0007143 biolink:AnatomicalEntity right internal carotid artery An internal carotid artery that branching_part_of a right common carotid artery plus branches. go-plus.json arteria carotis interna dextra http://purl.obolibrary.org/obo/UBERON_0007143 CHEBI:15335 biolink:ChemicalSubstance 5,7-dihydroxy-4'-methoxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_15335 UBERON:0007142 biolink:AnatomicalEntity left internal carotid artery An internal carotid artery that branching_part_of a left common carotid artery plus branches. go-plus.json arteria caritis interna sinistra http://purl.obolibrary.org/obo/UBERON_0007142 GO:1904151 biolink:BiologicalProcess positive regulation of microglial cell mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity. go-plus.json up regulation of microglial cell mediated cytotoxicity|activation of microglial cell mediated cytotoxicity|up-regulation of microglial cell mediated cytotoxicity|upregulation of microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_1904151 CHEBI:15334 biolink:ChemicalSubstance N(alpha)-methyl-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_15334 GO:1904150 biolink:BiologicalProcess negative regulation of microglial cell mediated cytotoxicity Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity. go-plus.json down-regulation of microglial cell mediated cytotoxicity|inhibition of microglial cell mediated cytotoxicity|down regulation of microglial cell mediated cytotoxicity|downregulation of microglial cell mediated cytotoxicity http://purl.obolibrary.org/obo/GO_1904150 CHEBI:15337 biolink:ChemicalSubstance beta-alanopine go-plus.json http://purl.obolibrary.org/obo/CHEBI_15337 CHEBI:15333 biolink:ChemicalSubstance zeatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_15333 chebi_ph7_3 UBERON:0007148 biolink:AnatomicalEntity lumen of hindgut An anatomical cavity that surrounded_by a hindgut. go-plus.json hindgut lumen http://purl.obolibrary.org/obo/UBERON_0007148 CHEBI:64261 biolink:ChemicalSubstance lupanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64261 chebi_ph7_3 CHEBI:64260 biolink:ChemicalSubstance aminodeoxyfutalosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64260 CHEBI:88230 biolink:ChemicalSubstance autophagy inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_88230 CHEBI:64265 biolink:ChemicalSubstance (3R,6S)-6-hydroxy-3,7-dimethyloctanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64265 CHEBI:88232 biolink:ChemicalSubstance epoxypheophorbide a(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88232 CHEBI:132008 biolink:ChemicalSubstance 5,10-dihydrophenazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132008 chebi_ph7_3 CHEBI:88231 biolink:ChemicalSubstance beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88231 chebi_ph7_3 CHEBI:64264 biolink:ChemicalSubstance 3-isopropenyl-6-oxoheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64264 CHEBI:64263 biolink:ChemicalSubstance 5-guanidino-3-methyl-2-oxopentanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64263 chebi_ph7_3 CHEBI:88234 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88234 chebi_ph7_3 CHEBI:64262 biolink:ChemicalSubstance 17-hydroxylupanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64262 chebi_ph7_3 CHEBI:88233 biolink:ChemicalSubstance epoxypheophorbide a(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88233 chebi_ph7_3 CHEBI:64268 biolink:ChemicalSubstance erythromycin A(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64268 chebi_ph7_3 CHEBI:88235 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88235 chebi_ph7_3 CHEBI:64267 biolink:ChemicalSubstance 5-methyltetrahydrosarcinapterin(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64267 chebi_ph7_3 CHEBI:88238 biolink:ChemicalSubstance (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88238 chebi_ph7_3 CHEBI:64266 biolink:ChemicalSubstance tricyclene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64266 chebi_ph7_3 CHEBI:88237 biolink:ChemicalSubstance CDP-3,6-dideoxy-alpha-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_88237 CHEBI:132001 biolink:ChemicalSubstance cholesteryl octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132001 chebi_ph7_3 CHEBI:88239 biolink:ChemicalSubstance (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88239 chebi_ph7_3 CHEBI:132003 biolink:ChemicalSubstance (10aS)-10,10a-dihydrophenazine-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132003 chebi_ph7_3 CHEBI:132002 biolink:ChemicalSubstance cholesteryl octadecadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132002 chebi_ph7_3 CHEBI:132005 biolink:ChemicalSubstance (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132005 chebi_ph7_3 CHEBI:132004 biolink:ChemicalSubstance cholesteryl octadecatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132004 chebi_ph7_3 CHEBI:132007 biolink:ChemicalSubstance cholesteryl icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132007 chebi_ph7_3 CHEBI:132006 biolink:ChemicalSubstance cholesteryl icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132006 chebi_ph7_3 NCBITaxon:3055 biolink:OrganismalEntity Chlamydomonas reinhardtii go-plus.json Chlamydomonas smithii http://purl.obolibrary.org/obo/NCBITaxon_3055 NCBITaxon:3052 biolink:OrganismalEntity Chlamydomonas go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3052 NCBITaxon:3051 biolink:OrganismalEntity Chlamydomonadaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3051 PR:000016876 biolink:Protein thymidylate synthase A protein that is a translation product of the human TYMS gene or a 1:1 ortholog thereof. go-plus.json TS|thyA|TSase|TYMS http://purl.obolibrary.org/obo/PR_000016876 CHEBI:64272 biolink:ChemicalSubstance tunicamycin D2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64272 chebi_ph7_3 CHEBI:64271 biolink:ChemicalSubstance tunicamycin D1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64271 chebi_ph7_3 CHEBI:64270 biolink:ChemicalSubstance cyclic dehypoxanthinylfutalosinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64270 chebi_ph7_3 CHEBI:88221 biolink:ChemicalSubstance N(omega),N('omega)-dimethyl-L-arginine(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_88221 chebi_ph7_3 CHEBI:132019 biolink:ChemicalSubstance 16-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132019 chebi_ph7_3 CHEBI:64274 biolink:ChemicalSubstance 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_64274 chebi_ph7_3 CHEBI:88222 biolink:ChemicalSubstance N(5)-methyl-argininium(1+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_88222 chebi_ph7_3 CHEBI:64273 biolink:ChemicalSubstance erythromycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_64273 CHEBI:64279 biolink:ChemicalSubstance erythromycin B(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64279 chebi_ph7_3 CHEBI:64278 biolink:ChemicalSubstance Reactive Blue 5 quinol form(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64278 chebi_ph7_3 CHEBI:88226 biolink:ChemicalSubstance (2E,6E)-farnesyl monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88226 chebi_ph7_3 CHEBI:64277 biolink:ChemicalSubstance 7,8-dihydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64277 chebi_ph7_3 CHEBI:88229 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88229 chebi_ph7_3 CHEBI:132012 biolink:ChemicalSubstance S-hexanoyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132012 chebi_ph7_3 CHEBI:88228 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88228 chebi_ph7_3 CHEBI:132011 biolink:ChemicalSubstance S-butyryl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132011 chebi_ph7_3 CHEBI:132014 biolink:ChemicalSubstance S-decanoyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132014 chebi_ph7_3 CHEBI:132013 biolink:ChemicalSubstance S-octanoyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132013 chebi_ph7_3 CHEBI:132016 biolink:ChemicalSubstance 17-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132016 chebi_ph7_3 CHEBI:132015 biolink:ChemicalSubstance S-dodecanoyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132015 chebi_ph7_3 CHEBI:132018 biolink:ChemicalSubstance S-hexadecanoyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132018 chebi_ph7_3 CHEBI:132017 biolink:ChemicalSubstance S-tetradecanoyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132017 chebi_ph7_3 GO:0052502 biolink:BiologicalProcess obsolete positive regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json activation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|upregulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|stimulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|up-regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|activation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|upregulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|induction by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|up regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052502 GO:0052501 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052501 GO:0052500 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont apoptosis OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of symbiont apoptosis|positive regulation by organism of symbiont apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052500 GO:0052506 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json upregulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|induction by organism of defense-related symbiont ethylene-mediated signal transduction pathway|activation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052506 CHEBI:64283 biolink:ChemicalSubstance copal-8-ol diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64283 chebi_ph7_3 CHEBI:88250 biolink:ChemicalSubstance 6-deoxy-6-sulfoglucono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_88250 GO:0052505 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont cell wall callose deposition OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related symbiont cell wall callose deposition|induction by organism of defense-related symbiont cell wall callose deposition http://purl.obolibrary.org/obo/GO_0052505 CHEBI:39282 biolink:ChemicalSubstance iodomethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39282 chebi_ph7_3 CHEBI:64282 biolink:ChemicalSubstance (Z)-biformene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64282 chebi_ph7_3 GO:0052504 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont callose deposition OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of defense-related symbiont callose deposition|positive regulation by organism of defense-related papilla formation in symbiont|positive regulation by organism of defense-related symbiont callose deposition|induction by organism of defense-related papilla formation in symbiont http://purl.obolibrary.org/obo/GO_0052504 NCBITaxon:3027 biolink:OrganismalEntity Cryptophyceae go-plus.json Cryptophyta|Chromophyta|cryptomonads|cryptomonads|cryptophytes|algae|Cryptomonadida http://purl.obolibrary.org/obo/NCBITaxon_3027 CHEBI:39281 biolink:ChemicalSubstance fluoromethanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_39281 CHEBI:88252 biolink:ChemicalSubstance (11Z,14Z)-icosadienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88252 chebi_ph7_3 GO:0052503 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the symbiont calcium-dependent protein kinase pathway during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of defense-related symbiont CDPK pathway by organism|positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway http://purl.obolibrary.org/obo/GO_0052503 CHEBI:88251 biolink:ChemicalSubstance (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88251 chebi_ph7_3 CHEBI:64280 biolink:ChemicalSubstance (E)-beta-ocimene go-plus.json http://purl.obolibrary.org/obo/CHEBI_64280 chebi_ph7_3 CHEBI:64287 biolink:ChemicalSubstance 17-hydroxylupanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64287 CHEBI:88254 biolink:ChemicalSubstance (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88254 chebi_ph7_3 GO:0052509 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052509 CHEBI:88253 biolink:ChemicalSubstance (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88253 chebi_ph7_3 CHEBI:64286 biolink:ChemicalSubstance aminodeoxyfutalosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64286 chebi_ph7_3 GO:0052508 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|activation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052508 CHEBI:64285 biolink:ChemicalSubstance (-)-bornyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64285 chebi_ph7_3 GO:0052507 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway http://purl.obolibrary.org/obo/GO_0052507 CHEBI:64284 biolink:ChemicalSubstance 1,4-dihydroxy-6-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64284 CHEBI:88257 biolink:ChemicalSubstance (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88257 chebi_ph7_3 CHEBI:64289 biolink:ChemicalSubstance 5-methyltetrahydrosarcinapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64289 CHEBI:88259 biolink:ChemicalSubstance (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88259 chebi_ph7_3 CHEBI:64288 biolink:ChemicalSubstance 5-guanidino-3-methyl-2-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64288 CHEBI:39276 biolink:ChemicalSubstance fumigant go-plus.json http://purl.obolibrary.org/obo/CHEBI_39276 CHEBI:39275 biolink:ChemicalSubstance bromomethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39275 chebi_ph7_3 CHEBI:39279 biolink:ChemicalSubstance halomethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39279 CHEBI:39278 biolink:ChemicalSubstance bromomethanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_39278 CHEBI:39277 biolink:ChemicalSubstance fumigant insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39277 GO:0052513 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052513 CHEBI:64290 biolink:ChemicalSubstance erythromycin cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_64290 GO:0052512 biolink:BiologicalProcess obsolete positive regulation by organism of hormone or growth regulator levels in symbiont OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of hormone or growth regulator levels in symbiont|positive modulation of hormone or growth regulator levels in symbiont http://purl.obolibrary.org/obo/GO_0052512 GO:0052511 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont ethylene-mediated defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of symbiont ethylene-mediated defense response|upregulation by organism of symbiont ethylene-mediated defense response|activation by organism of symbiont ethylene-mediated defense response|positive regulation by organism of symbiont ethylene-mediated defense response http://purl.obolibrary.org/obo/GO_0052511 GO:0052510 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052510 GO:0052517 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont non-apoptotic programmed cell death OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of symbiont non-apoptotic programmed cell death http://purl.obolibrary.org/obo/GO_0052517 CHEBI:64294 biolink:ChemicalSubstance 7-ketocholesterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64294 chebi_ph7_3 GO:0052516 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont jasmonic acid-mediated defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json induction by organism of symbiont jasmonic acid-mediated defense response|positive regulation by organism of symbiont JA-mediated defense response|induction by organism of symbiont JA-mediated defense response|positive regulation by organism of symbiont jasmonic acid-mediated defense response http://purl.obolibrary.org/obo/GO_0052516 CHEBI:64293 biolink:ChemicalSubstance copal-8-ol diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64293 GO:0052515 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont innate immunity OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation of symbiont innate immune response|positive regulation by organism of symbiont innate immunity http://purl.obolibrary.org/obo/GO_0052515 CHEBI:88241 biolink:ChemicalSubstance (9Z,12E)-octadecadienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88241 chebi_ph7_3 CHEBI:64292 biolink:ChemicalSubstance coniferyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_64292 chebi_ph7_3 GO:0052514 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont inflammatory response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of symbiont inflammatory response http://purl.obolibrary.org/obo/GO_0052514 CHEBI:64291 biolink:ChemicalSubstance Reactive Blue 5 quinol form go-plus.json http://purl.obolibrary.org/obo/CHEBI_64291 CHEBI:88240 biolink:ChemicalSubstance oleoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88240 chebi_ph7_3 CHEBI:64298 biolink:ChemicalSubstance (-)-bornyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64298 CHEBI:88243 biolink:ChemicalSubstance UDP-beta-L-iduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88243 NCBITaxon:487 biolink:OrganismalEntity Neisseria meningitidis go-plus.json Micrococcus meningitidis cerebrospinalis|Micrococcus meningitidis|Micrococcus intracellularis|Neisseria weichselbaumii|Diplokokkus intracellularis meningitidis http://purl.obolibrary.org/obo/NCBITaxon_487 CHEBI:88242 biolink:ChemicalSubstance (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88242 chebi_ph7_3 GO:0052519 biolink:BiologicalProcess positive regulation by host of nutrient release from symbiont Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json upregulation by host of nutrient release from symbiont|stimulation by host of nutrient release from symbiont|up-regulation by host of nutrient release from symbiont|activation by host of nutrient release from symbiont|promotion of nutrient release from symbiont|up regulation by host of nutrient release from symbiont http://purl.obolibrary.org/obo/GO_0052519 CHEBI:88245 biolink:ChemicalSubstance prenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88245 CHEBI:88244 biolink:ChemicalSubstance (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88244 chebi_ph7_3 GO:0052518 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052518 CHEBI:88247 biolink:ChemicalSubstance [5-(aminomethyl)-3-furyl]methyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88247 CHEBI:88248 biolink:ChemicalSubstance (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88248 NCBITaxon:482 biolink:OrganismalEntity Neisseria go-plus.json "Merismopedia" Zopf 1885|Gonococcus http://purl.obolibrary.org/obo/NCBITaxon_482 NCBITaxon:481 biolink:OrganismalEntity Neisseriaceae go-plus.json Vitreoscillaceae http://purl.obolibrary.org/obo/NCBITaxon_481 NCBITaxon:3042 biolink:OrganismalEntity Chlamydomonadales go-plus.json Chlorococcales|Volvocales|Volvocida http://purl.obolibrary.org/obo/NCBITaxon_3042 CHEBI:39284 biolink:ChemicalSubstance iodomethanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_39284 NCBITaxon:3041 biolink:OrganismalEntity Chlorophyta go-plus.json green algae|Chlorophyta sensu Bremer 1985|green algae|algae|Chlorophycota http://purl.obolibrary.org/obo/NCBITaxon_3041 GO:0052524 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont salicylic acid-mediated defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of symbiont SA-mediated defense response|induction by organism of symbiont salicylic acid-mediated defense response|induction by organism of symbiont SA-mediated defense response|positive regulation by organism of symbiont salicylic acid-mediated defense response http://purl.obolibrary.org/obo/GO_0052524 GO:0052523 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont programmed cell death OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json enhancement or induction of symbiont programmed cell death|positive regulation by organism of symbiont programmed cell death http://purl.obolibrary.org/obo/GO_0052523 CHEBI:88270 biolink:ChemicalSubstance 6-deoxy-6-sulfo-D-gluconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88270 GO:0052522 biolink:BiologicalProcess obsolete positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction. go-plus.json upregulation by organism of phagocytosis in other organism during symbiotic interaction|positive regulation by organism of phagocytosis in other organism during symbiotic interaction|activation by organism of phagocytosis in other organism during symbiotic interaction|stimulation by organism of phagocytosis in other organism during symbiotic interaction|up regulation by organism of phagocytosis in other organism during symbiotic interaction|up-regulation by organism of phagocytosis in other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052522 GO:0052521 biolink:BiologicalProcess obsolete positive regulation by host of symbiont phagocytosis OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json upregulation by host of symbiont phagocytosis|up regulation by host of symbiont phagocytosis|activation by host of symbiont phagocytosis|stimulation by host of symbiont phagocytosis|up-regulation by host of symbiont phagocytosis http://purl.obolibrary.org/obo/GO_0052521 GO:0052528 biolink:BiologicalProcess obsolete upregulation by organism of symbiont programmed cell death OBSOLETE. Any process by which an organism increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json upregulation by organism of symbiont programmed cell death|enhancement of symbiont programmed cell death by organism http://purl.obolibrary.org/obo/GO_0052528 GO:0052527 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052527 GO:0052526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052526 GO:0052525 biolink:BiologicalProcess obsolete positive regulation by host of symbiont signal transduction pathway OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json up-regulation by host of symbiont signal transduction pathway|activation by host of symbiont signal transduction pathway|up regulation by host of symbiont signal transduction pathway|upregulation by host of symbiont signal transduction pathway|stimulation by host of symbiont signal transduction pathway http://purl.obolibrary.org/obo/GO_0052525 CHEBI:88278 biolink:ChemicalSubstance N-acetylhexosaminyl-dihexosylceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_88278 CHEBI:88277 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_88277 GO:0052529 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052529 UBERON:0007213 biolink:AnatomicalEntity mesenchyme derived from head neural crest Mesenchyme that develops_from a cranial neural crest. go-plus.json head mesenchyme from cranial neural crest|head neural crest derived mesenchyme|head mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0007213 NCBITaxon:491 biolink:OrganismalEntity Neisseria meningitidis serogroup B go-plus.json Neisseria meningitidis (group B)|Neisseria meningitidis group B|Neisseria meningitidis (serogroup B) http://purl.obolibrary.org/obo/NCBITaxon_491 CHEBI:39259 biolink:ChemicalSubstance pyrethroid ester acaricide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39259 CHEBI:39252 biolink:ChemicalSubstance pyridophenoxazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39252 GO:0052520 biolink:BiologicalProcess positive regulation by organism of nutrient release from other organism involved in symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction. go-plus.json up-regulation by organism of nutrient release from other organism during symbiotic interaction|promotion of nutrient release from other organism|upregulation by organism of nutrient release from other organism during symbiotic interaction|activation by organism of nutrient release from other organism during symbiotic interaction|positive regulation by organism of nutrient release from other organism during symbiotic interaction|up regulation by organism of nutrient release from other organism during symbiotic interaction|stimulation by organism of nutrient release from other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0052520 CHEBI:39258 biolink:ChemicalSubstance diphenyl ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_39258 chebi_ph7_3 UBERON:0007214 biolink:AnatomicalEntity mesenchyme derived from trunk neural crest Mesenchyme that develops_from a trunk neural crest. go-plus.json trunk mesenchyme from neural crest|trunk neural crest derived mesenchyme http://purl.obolibrary.org/obo/UBERON_0007214 GO:0052535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052535 CHEBI:171664 biolink:ChemicalSubstance antiamoebic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_171664 GO:0052534 biolink:BiologicalProcess obsolete positive regulation by organism of induced systemic resistance in symbiont OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of induced systemic resistance in symbiont http://purl.obolibrary.org/obo/GO_0052534 GO:0052533 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052533 GO:0052532 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052532 GO:0052539 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052539 CHEBI:88261 biolink:ChemicalSubstance palmitoleoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88261 chebi_ph7_3 GO:0052538 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052538 CHEBI:88260 biolink:ChemicalSubstance (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88260 chebi_ph7_3 CHEBI:39270 biolink:ChemicalSubstance naphthofuran go-plus.json http://purl.obolibrary.org/obo/CHEBI_39270 GO:0052537 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052537 GO:0052536 biolink:BiologicalProcess obsolete positive regulation by organism of systemic acquired resistance in symbiont OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of systemic acquired resistance in symbiont http://purl.obolibrary.org/obo/GO_0052536 CHEBI:88262 biolink:ChemicalSubstance (9Z,12E)-hexadecadienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88262 chebi_ph7_3 CHEBI:88265 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88265 chebi_ph7_3 NCBITaxon:651137 biolink:OrganismalEntity Thaumarchaeota go-plus.json Nitrososphaerota|Nitrososphaeraeota http://purl.obolibrary.org/obo/NCBITaxon_651137 CHEBI:88264 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88264 chebi_ph7_3 CHEBI:88267 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88267 chebi_ph7_3 CHEBI:88266 biolink:ChemicalSubstance (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88266 chebi_ph7_3 CHEBI:88269 biolink:ChemicalSubstance (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88269 chebi_ph7_3 CHEBI:88268 biolink:ChemicalSubstance (7Z,10Z)-hexadecadienoyl-containing glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88268 chebi_ph7_3 GO:0052531 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont calcium ion flux OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related symbiont calcium ion flux|positive regulation by organism of defense-related symbiont Ca2+ flux http://purl.obolibrary.org/obo/GO_0052531 GO:0052530 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont resistance gene-dependent defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense response in symbiont by specific elicitors|positive regulation by organism of symbiont resistance gene-dependent defense response|positive regulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|positive regulation by organism of symbiont gene-for-gene resistance http://purl.obolibrary.org/obo/GO_0052530 CHEBI:39268 biolink:ChemicalSubstance dibenzothiazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39268 UBERON:0007204 biolink:AnatomicalEntity brachiocephalic vasculature The vasculature consisting of brachiocephalic arteries and veins. go-plus.json http://purl.obolibrary.org/obo/UBERON_0007204 GO:0052546 biolink:BiologicalProcess cell wall pectin metabolic process The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall. go-plus.json cellulose and pectin-containing cell wall pectin metabolic process|pectin metabolism during cell wall biogenesis|plant-type cell wall pectin metabolic process|cell wall pectin metabolism http://purl.obolibrary.org/obo/GO_0052546 GO:0052545 biolink:BiologicalProcess callose localization Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. go-plus.json callose localisation http://purl.obolibrary.org/obo/GO_0052545 GO:0052544 biolink:BiologicalProcess defense response by callose deposition in cell wall Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. go-plus.json callose localization in cell wall during defense response|callose deposition in cell wall during defense response|cell wall callose localization during defense response|cell wall callose deposition during defense response http://purl.obolibrary.org/obo/GO_0052544 CHEBI:88291 biolink:ChemicalSubstance hydroxyimidazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_88291 GO:0052543 biolink:BiologicalProcess callose deposition in cell wall Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. go-plus.json callose localization in cell wall|cell wall callose localization|cell wall callose deposition http://purl.obolibrary.org/obo/GO_0052543 GO:0052549 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052549 GO:0052548 biolink:BiologicalProcess regulation of endopeptidase activity Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. go-plus.json protease regulator activity http://purl.obolibrary.org/obo/GO_0052548 GO:0052547 biolink:BiologicalProcess regulation of peptidase activity Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. go-plus.json peptidase regulator activity http://purl.obolibrary.org/obo/GO_0052547 CHEBI:39237 biolink:ChemicalSubstance farnesene go-plus.json http://purl.obolibrary.org/obo/CHEBI_39237 CHEBI:40235 biolink:ChemicalSubstance 9H-purine-2,6-diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_40235 chebi_ph7_3 GO:0052542 biolink:BiologicalProcess defense response by callose deposition Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. go-plus.json callose deposition during defense response|callose localization during defense response http://purl.obolibrary.org/obo/GO_0052542 CHEBI:39236 biolink:ChemicalSubstance alpha-farnesene go-plus.json http://purl.obolibrary.org/obo/CHEBI_39236 chebi_ph7_3 GO:0052541 biolink:BiologicalProcess plant-type cell wall cellulose metabolic process The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall. go-plus.json cell wall cellulose metabolism|cellulose and pectin-containing cell wall cellulose metabolic process http://purl.obolibrary.org/obo/GO_0052541 GO:0052540 biolink:BiologicalProcess obsolete positive regulation by organism of defense-related symbiont cell wall thickening OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of defense-related symbiont cell wall thickening|positive regulation by organism of symbiont defensive cell wall thickening http://purl.obolibrary.org/obo/GO_0052540 GO:0052557 biolink:BiologicalProcess obsolete positive regulation by organism of symbiont immune response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by organism of symbiont immune response http://purl.obolibrary.org/obo/GO_0052557 GO:0052556 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052556 GO:0052555 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052555 GO:0052554 biolink:BiologicalProcess obsolete modulation by organism of symbiont immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of symbiont immune response http://purl.obolibrary.org/obo/GO_0052554 CHEBI:39250 biolink:ChemicalSubstance isopentadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39250 GO:0052559 biolink:BiologicalProcess induction by symbiont of host immune response Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json positive regulation by symbiont of host immune response|up regulation by symbiont of host immune response|positive regulation by organism of immune response of other organism involved in symbiotic interaction|upregulation by symbiont of host immune response|up-regulation by symbiont of host immune response|induction by organism of immune response of other organism involved in symbiotic interaction|activation by symbiont of host immune response|stimulation by symbiont of host immune response http://purl.obolibrary.org/obo/GO_0052559 GO:0052558 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052558 CHEBI:39241 biolink:ChemicalSubstance beta-farnesene go-plus.json http://purl.obolibrary.org/obo/CHEBI_39241 chebi_ph7_3 GO:0052553 biolink:BiologicalProcess modulation by symbiont of host immune response Any process in which a symbiont modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json modulation by organism of immune response of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052553 GO:0052552 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052552 CHEBI:39246 biolink:ChemicalSubstance nonadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39246 GO:0052551 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052551 GO:0052550 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052550 CHEBI:78826 biolink:ChemicalSubstance O-(S-3-oxononanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78826 chebi_ph7_3 CHEBI:78824 biolink:ChemicalSubstance O-(S-3-oxoheptanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78824 chebi_ph7_3 CHEBI:78823 biolink:ChemicalSubstance O-(S-3-oxo-4-methylhexanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78823 chebi_ph7_3 CHEBI:132090 biolink:ChemicalSubstance O(3)-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132090 chebi_ph7_3 CHEBI:78827 biolink:ChemicalSubstance O-[S-(3R)-3-hydroxyacylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78827 chebi_ph7_3 CHEBI:132088 biolink:ChemicalSubstance O(3)-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132088 chebi_ph7_3 CHEBI:132081 biolink:ChemicalSubstance 17-oxoresolvin D1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132081 chebi_ph7_3 CHEBI:132080 biolink:ChemicalSubstance 8-oxoresolvin D1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132080 chebi_ph7_3 CHEBI:132083 biolink:ChemicalSubstance 18(S)-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132083 chebi_ph7_3 CHEBI:132085 biolink:ChemicalSubstance O(3)-(beta-D-xylosyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132085 chebi_ph7_3 CHEBI:78822 biolink:ChemicalSubstance O-(S-3-oxo-5-methylhexanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78822 chebi_ph7_3 CHEBI:132087 biolink:ChemicalSubstance 15(S)-HEPE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132087 chebi_ph7_3 CHEBI:78820 biolink:ChemicalSubstance O-(S-3-oxo-4-methylpentanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78820 chebi_ph7_3 CHEBI:78837 biolink:ChemicalSubstance 15(R)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78837 chebi_ph7_3 CHEBI:78836 biolink:ChemicalSubstance 11(R)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78836 chebi_ph7_3 CHEBI:132091 biolink:ChemicalSubstance (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132091 chebi_ph7_3 CHEBI:132093 biolink:ChemicalSubstance O(3)-(beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_132093 chebi_ph7_3 CHEBI:78833 biolink:ChemicalSubstance 11-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78833 chebi_ph7_3 CHEBI:78832 biolink:ChemicalSubstance (5Z,8Z,11Z,13E)-15-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78832 chebi_ph7_3 CHEBI:78847 biolink:ChemicalSubstance UDP-2,3-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78847 chebi_ph7_3 CHEBI:78846 biolink:ChemicalSubstance O-(S-pimeloylpantetheine-4'-phosphoryl)serine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78846 chebi_ph7_3 CHEBI:78845 biolink:ChemicalSubstance O-[S-(methoxycarbonylacetyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78845 chebi_ph7_3 CHEBI:132067 biolink:ChemicalSubstance (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132067 chebi_ph7_3 CHEBI:156034 biolink:ChemicalSubstance phosphatidylglycerol 38:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156034 CHEBI:156033 biolink:ChemicalSubstance phosphatidylglycerol 38:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156033 CHEBI:132066 biolink:ChemicalSubstance S-(1-hydroxy-2-methylbut-3-en-2-yl)glutathione go-plus.json http://purl.obolibrary.org/obo/CHEBI_132066 CHEBI:132069 biolink:ChemicalSubstance (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132069 CHEBI:156031 biolink:ChemicalSubstance phosphatidylglycerol 40:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156031 CHEBI:132068 biolink:ChemicalSubstance (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132068 chebi_ph7_3 CHEBI:156030 biolink:ChemicalSubstance phosphatidylglycerol 40:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156030 CHEBI:78840 biolink:ChemicalSubstance olefinic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_78840 CHEBI:132061 biolink:ChemicalSubstance N-[12(S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]taurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132061 chebi_ph7_3 CHEBI:132060 biolink:ChemicalSubstance N-arachidonoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132060 chebi_ph7_3 CHEBI:156039 biolink:ChemicalSubstance phosphatidylglycerol 44:12 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156039 CHEBI:132063 biolink:ChemicalSubstance (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132063 chebi_ph7_3 CHEBI:78844 biolink:ChemicalSubstance 3'-(N-formyl-L-methionyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78844 chebi_ph7_3 CHEBI:132062 biolink:ChemicalSubstance N-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]taurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132062 chebi_ph7_3 CHEBI:156037 biolink:ChemicalSubstance phosphatidylglycerol 42:8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156037 CHEBI:132065 biolink:ChemicalSubstance (12S)-hydroperoxy-(14S,15R)-epoxy-(5Z,8Z,10E)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132065 chebi_ph7_3 CHEBI:156036 biolink:ChemicalSubstance phosphatidylglycerol 40:7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156036 CHEBI:132064 biolink:ChemicalSubstance 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132064 chebi_ph7_3 CHEBI:156035 biolink:ChemicalSubstance phosphatidylglycerol 38:5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156035 CHEBI:78859 biolink:ChemicalSubstance 12(S)-HPE(5,8,10)TrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78859 CHEBI:78858 biolink:ChemicalSubstance (R)-2-methylpyrrolidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78858 CHEBI:78856 biolink:ChemicalSubstance 2-methyl-1-pyrroline go-plus.json http://purl.obolibrary.org/obo/CHEBI_78856 CHEBI:132078 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132078 chebi_ph7_3 CHEBI:132077 biolink:ChemicalSubstance N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132077 chebi_ph7_3 CHEBI:132079 biolink:ChemicalSubstance resolvin D1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132079 chebi_ph7_3 CHEBI:132070 biolink:ChemicalSubstance eoxin A4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132070 chebi_ph7_3 CHEBI:132072 biolink:ChemicalSubstance N-arachidonoyl-gamma-aminobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132072 chebi_ph7_3 CHEBI:156029 biolink:ChemicalSubstance phosphatidylglycerol 38:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_156029 CHEBI:132071 biolink:ChemicalSubstance N-arachidonoyl-L-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132071 chebi_ph7_3 CHEBI:132074 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132074 chebi_ph7_3 CHEBI:132073 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]glycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132073 chebi_ph7_3 CHEBI:132076 biolink:ChemicalSubstance N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]glycinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132076 chebi_ph7_3 CHEBI:132075 biolink:ChemicalSubstance N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132075 chebi_ph7_3 CHEBI:78869 biolink:ChemicalSubstance octacosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78869 CHEBI:78868 biolink:ChemicalSubstance octacosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78868 CHEBI:78867 biolink:ChemicalSubstance tetracosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78867 CHEBI:64221 biolink:ChemicalSubstance (3R,6S)-6-hydroxy-3,7-dimethyloctanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64221 chebi_ph7_3 CHEBI:64220 biolink:ChemicalSubstance monosodium glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64220 CHEBI:64225 biolink:ChemicalSubstance (3R,6R)-6-hydroxy-3-isopropenylheptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64225 chebi_ph7_3 CHEBI:64224 biolink:ChemicalSubstance 6-hydroxy-3-isopropenylheptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64224 chebi_ph7_3 CHEBI:64223 biolink:ChemicalSubstance 6-hydroxy-3,7-dimethyloctanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64223 chebi_ph7_3 CHEBI:64229 biolink:ChemicalSubstance 6-isopropenyl-3-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_64229 chebi_ph7_3 CHEBI:132045 biolink:ChemicalSubstance N-hexadecanoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132045 chebi_ph7_3 CHEBI:132044 biolink:ChemicalSubstance Deoxymethylsphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_132044 CHEBI:64228 biolink:ChemicalSubstance tunicamycin A0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64228 chebi_ph7_3 CHEBI:132047 biolink:ChemicalSubstance N-stearoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132047 chebi_ph7_3 CHEBI:132046 biolink:ChemicalSubstance Deoxysphingoid base go-plus.json http://purl.obolibrary.org/obo/CHEBI_132046 CHEBI:64226 biolink:ChemicalSubstance (3S,6R)-6-hydroxy-3-isopropenylheptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64226 chebi_ph7_3 CHEBI:132049 biolink:ChemicalSubstance N-tetracosanoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132049 chebi_ph7_3 CHEBI:132048 biolink:ChemicalSubstance N-icosanoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132048 chebi_ph7_3 CHEBI:78862 biolink:ChemicalSubstance tetracosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78862 CHEBI:78861 biolink:ChemicalSubstance 14(S)-HPDHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78861 CHEBI:78860 biolink:ChemicalSubstance 12(S)-HPE(8,10,14)TrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78860 CHEBI:78866 biolink:ChemicalSubstance hexacosahexaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78866 CHEBI:132040 biolink:ChemicalSubstance fatty acid-taurine conjugate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132040 chebi_ph7_3 CHEBI:78865 biolink:ChemicalSubstance hexacosenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78865 CHEBI:78864 biolink:ChemicalSubstance hexacosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78864 CHEBI:132043 biolink:ChemicalSubstance N-tetradecanoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132043 chebi_ph7_3 CHEBI:132042 biolink:ChemicalSubstance N-dodecanoyltaurine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132042 chebi_ph7_3 CHEBI:78863 biolink:ChemicalSubstance hexacosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78863 CHEBI:64232 biolink:ChemicalSubstance (3S,6R)-6-isopropenyl-3-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_64232 chebi_ph7_3 CHEBI:64230 biolink:ChemicalSubstance (3R,6S)-6-isopropenyl-3-methyloxepan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_64230 chebi_ph7_3 CHEBI:64236 biolink:ChemicalSubstance (6E)-8-oxogeraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64236 chebi_ph7_3 CHEBI:64235 biolink:ChemicalSubstance (6E)-8-hydroxygeraniol go-plus.json http://purl.obolibrary.org/obo/CHEBI_64235 chebi_ph7_3 CHEBI:64234 biolink:ChemicalSubstance 3-isopropenyl-6-oxoheptanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64234 chebi_ph7_3 CHEBI:64239 biolink:ChemicalSubstance (6E)-8-oxogeranial go-plus.json http://purl.obolibrary.org/obo/CHEBI_64239 chebi_ph7_3 CHEBI:64238 biolink:ChemicalSubstance (6E)-8-hydroxygeranial go-plus.json http://purl.obolibrary.org/obo/CHEBI_64238 chebi_ph7_3 CHEBI:64237 biolink:ChemicalSubstance EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64237 PR:000002201 biolink:Protein dynein light chain A protein that is a translation product of the human DYNLL1 or DYNLL2 genes, or 1:1 orthologs thereof. The protein is small (89 residues in human and mouse) with core architecture consisting of a Dynein light chain type 1 domain (Pfam:PF01221). go-plus.json http://purl.obolibrary.org/obo/PR_000002201 PR:000002204 biolink:Protein lymphotoxin-alpha A lymphotoxin that is a translation product of the human LTA gene or a 1:1 ortholog thereof. go-plus.json LT-alpha|LTA|TNFB|TNF-beta|TNFSF1|tumor necrosis factor B|tumor necrosis factor ligand superfamily member 1 http://purl.obolibrary.org/obo/PR_000002204 CHEBI:132052 biolink:ChemicalSubstance (S)-demethyl-4-deoxygadusol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132052 CHEBI:64243 biolink:ChemicalSubstance monosodium L-glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64243 CHEBI:64241 biolink:ChemicalSubstance (6R)-L-threo-tetrahydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64241 chebi_ph7_3 CHEBI:64240 biolink:ChemicalSubstance L-threo-7,8-dihydrobiopterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64240 chebi_ph7_3 CHEBI:64247 biolink:ChemicalSubstance (3R,6R)-6-hydroxy-3-isopropenylheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64247 CHEBI:64246 biolink:ChemicalSubstance tunicamycin A2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64246 chebi_ph7_3 CHEBI:64245 biolink:ChemicalSubstance tunicamycin A1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64245 chebi_ph7_3 CHEBI:64244 biolink:ChemicalSubstance monosodium D-glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64244 CHEBI:132023 biolink:ChemicalSubstance S-acyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132023 chebi_ph7_3 CHEBI:132022 biolink:ChemicalSubstance 12-hydroxyjasmonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132022 chebi_ph7_3 CHEBI:132025 biolink:ChemicalSubstance 21-HDoHE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132025 chebi_ph7_3 CHEBI:64249 biolink:ChemicalSubstance (3S,6R)-6-hydroxy-3-isopropenylheptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64249 CHEBI:64248 biolink:ChemicalSubstance tunicamycin B1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64248 chebi_ph7_3 CHEBI:132024 biolink:ChemicalSubstance 19-HETrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132024 chebi_ph7_3 CHEBI:132026 biolink:ChemicalSubstance 20-HETrE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132026 chebi_ph7_3 CHEBI:132028 biolink:ChemicalSubstance tauroursodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132028 chebi_ph7_3 CHEBI:78882 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acylglycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78882 chebi_ph7_3 CHEBI:132021 biolink:ChemicalSubstance S-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl)-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132021 chebi_ph7_3 CHEBI:132020 biolink:ChemicalSubstance S-choloyl-4'-phosphopantetheine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132020 chebi_ph7_3 CHEBI:64250 biolink:ChemicalSubstance tunicamycin B2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64250 chebi_ph7_3 CHEBI:64254 biolink:ChemicalSubstance 1,4-dihydroxy-6-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64254 chebi_ph7_3 CHEBI:64253 biolink:ChemicalSubstance 3-demethylubiquinol-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64253 chebi_ph7_3 CHEBI:64252 biolink:ChemicalSubstance cyclic dehypoxanthinylfutalosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_64252 CHEBI:64258 biolink:ChemicalSubstance erythromycin C(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64258 chebi_ph7_3 CHEBI:64257 biolink:ChemicalSubstance tunicamycin C2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64257 chebi_ph7_3 CHEBI:64256 biolink:ChemicalSubstance tunicamycin C1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64256 chebi_ph7_3 CHEBI:64255 biolink:ChemicalSubstance tunicamycin B3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64255 chebi_ph7_3 CHEBI:64259 biolink:ChemicalSubstance (6E)-8-oxolinalool go-plus.json http://purl.obolibrary.org/obo/CHEBI_64259 chebi_ph7_3 CHEBI:78892 biolink:ChemicalSubstance fatty acid anion 19:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78892 chebi_ph7_3 CHEBI:132030 biolink:ChemicalSubstance glycoursodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132030 chebi_ph7_3 CHEBI:78896 biolink:ChemicalSubstance tetradecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78896 chebi_ph7_3 CHEBI:132031 biolink:ChemicalSubstance 13-hydroxytetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132031 chebi_ph7_3 CHEBI:30801 biolink:ChemicalSubstance terephthalate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30801 CHEBI:30800 biolink:ChemicalSubstance phthalate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30800 GO:0062091 biolink:CellularComponent Ycf2/FtsHi complex A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma. go-plus.json TIC complex associated chloroplast protein import motor http://purl.obolibrary.org/obo/GO_0062091 GO:0062090 biolink:BiologicalProcess positive regulation of taurine biosynthetic process Any process that activates or increases the frequency, rate or extent of taurine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0062090 GO:0062093 biolink:BiologicalProcess lysophagy The selective autophagy process in which a damaged lysosome is degraded by macroautophagy. go-plus.json http://purl.obolibrary.org/obo/GO_0062093 GO:0062092 biolink:CellularComponent Yae1-Lto1 complex A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p. go-plus.json http://purl.obolibrary.org/obo/GO_0062092 GO:0062095 biolink:BiologicalProcess endoplasmic reticulum-peroxisome tethering The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other. go-plus.json http://purl.obolibrary.org/obo/GO_0062095 GO:0062094 biolink:BiologicalProcess stomach development The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. go-plus.json http://purl.obolibrary.org/obo/GO_0062094 GO:0062097 biolink:BiologicalProcess chemosynthesis The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane. Wikipedia:Chemosynthesis go-plus.json http://purl.obolibrary.org/obo/GO_0062097 GO:0062096 biolink:BiologicalProcess kinetochore disassembly The disaggregation of a kinetochore into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0062096 GO:0062099 biolink:BiologicalProcess negative regulation of programmed necrotic cell death Any process that decreases the frequency, rate or extent of programmed necrotic cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0062099 CHEBI:30807 biolink:ChemicalSubstance tetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30807 chebi_ph7_3 GO:0062098 biolink:BiologicalProcess regulation of programmed necrotic cell death Any process that modulates the frequency, rate or extent of programmed necrotic cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0062098 NCBITaxon:27896 biolink:OrganismalEntity Planariidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_27896 CHEBI:30805 biolink:ChemicalSubstance dodecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30805 GO:0086059 biolink:MolecularActivity voltage-gated calcium channel activity involved SA node cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated calcium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in SAN cardiac muscle cell action potential|voltage-gated calcium channel activity involved in SA node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086059 GO:0086058 biolink:MolecularActivity voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086058 GO:0086057 biolink:MolecularActivity voltage-gated calcium channel activity involved in bundle of His cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated calcium channel activity involved in bundle of His cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086057 GO:0086056 biolink:MolecularActivity voltage-gated calcium channel activity involved in AV node cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated calcium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086056 GO:0086055 biolink:BiologicalProcess Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json http://purl.obolibrary.org/obo/GO_0086055 GO:0086054 biolink:BiologicalProcess bundle of His cell to Purkinje myocyte communication by electrical coupling The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json bundle of His cardiac muscle cell to Purkinje myocyte communication by electrical coupling http://purl.obolibrary.org/obo/GO_0086054 GO:0086053 biolink:BiologicalProcess AV node cell to bundle of His cell communication by electrical coupling The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json atrioventricular node cell to bundle of His cell communication by electrical coupling http://purl.obolibrary.org/obo/GO_0086053 GO:0086052 biolink:BiologicalProcess membrane repolarization during SA node cell action potential The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json membrane repolarization involved in regulation of SAN cardiac muscle cell action potential|membrane repolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane repolarization involved in regulation of SA node cardiac muscle cell action potential|membrane repolarization involved in regulation of sinoatrial node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086052 GO:0086051 biolink:BiologicalProcess membrane repolarization during Purkinje myocyte action potential The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086051 GO:0086050 biolink:BiologicalProcess membrane repolarization during bundle of His cell action potential The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json membrane repolarization during bundle of His cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086050 CHEBI:30814 biolink:ChemicalSubstance digallic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30814 CHEBI:30813 biolink:ChemicalSubstance decanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30813 GO:0062080 biolink:MolecularActivity inhibitory MHC class Ib receptor activity Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0062080 GO:0062082 biolink:MolecularActivity HLA-E specific inhibitory MHC class Ib receptor activity Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0062082 GO:0062081 biolink:MolecularActivity activating MHC class Ib receptor activity Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0062081 GO:0062084 biolink:BiologicalProcess regulation of capsule polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0062084 GO:0062083 biolink:MolecularActivity HLA-G specific inhibitory MHC class Ib receptor activity Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0062083 GO:0062086 biolink:BiologicalProcess regulation of vein smooth muscle contraction Any process that modulates the frequency, rate or extent of vein smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0062086 GO:0062085 biolink:BiologicalProcess positive regulation of capsule polysaccharide biosynthetic process Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi. go-plus.json http://purl.obolibrary.org/obo/GO_0062085 GO:0062088 biolink:BiologicalProcess negative regulation of vein smooth muscle contraction Any process that decreases the frequency, rate or extent of vein smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0062088 GO:0062087 biolink:BiologicalProcess positive regulation of vein smooth muscle contraction Any process that increases the frequency, rate or extent of vein smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0062087 CHEBI:30817 biolink:ChemicalSubstance trans-urocanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30817 GO:0062089 biolink:BiologicalProcess regulation of taurine biosynthetic process Any process that modulates the rate, frequency or extent of taurine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0062089 GO:0086049 biolink:BiologicalProcess membrane repolarization during AV node cell action potential The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json membrane repolarization involved in regulation of atrioventricular node cardiac muscle cell action potential|membrane repolarization involved in regulation of AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086049 CHEBI:30816 biolink:ChemicalSubstance vanillic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30816 GO:0086048 biolink:BiologicalProcess membrane depolarization during bundle of His cell action potential The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json membrane depolarization during bundle of His cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086048 GO:0086047 biolink:BiologicalProcess membrane depolarization during Purkinje myocyte cell action potential The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086047 GO:0086046 biolink:BiologicalProcess membrane depolarization during SA node cell action potential The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json membrane depolarization involved in regulation of SAN cardiac muscle cell action potential|membrane depolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane depolarization involved in regulation of SA node cardiac muscle cell action potential|membrane depolarization involved in regulation of sinoatrial node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086046 GO:0086045 biolink:BiologicalProcess membrane depolarization during AV node cell action potential The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json membrane depolarization during AV node cardiac muscle cell action potential|membrane depolarization during atrioventricular node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086045 CHEBI:8602 biolink:ChemicalSubstance pseudobaptigenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8602 GO:0086044 biolink:BiologicalProcess atrial cardiac muscle cell to AV node cell communication by electrical coupling The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json atrial cardiomyocyte to atrioventricular node cell communication by electrical coupling|atrial cardiomyocyte to AV node cell communication by electrical coupling http://purl.obolibrary.org/obo/GO_0086044 GO:0086043 biolink:BiologicalProcess bundle of His cell action potential An action potential that occurs in a bundle of His cell. go-plus.json bundle of His cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086043 GO:0086042 biolink:BiologicalProcess cardiac muscle cell-cardiac muscle cell adhesion The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules. go-plus.json cardiomyocyte-cardiomyocyte adhesion http://purl.obolibrary.org/obo/GO_0086042 GO:0086041 biolink:MolecularActivity voltage-gated potassium channel activity involved in SA node cell action potential depolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated potassium channel activity involved in SAN cell action potential depolarization|voltage-gated potassium channel activity involved in sinus node cell action potential depolarization|voltage-gated potassium channel activity involved in sinoatrial node cell action potential depolarization http://purl.obolibrary.org/obo/GO_0086041 GO:0086040 biolink:MolecularActivity sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential. go-plus.json sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential http://purl.obolibrary.org/obo/GO_0086040 GO:0086079 biolink:MolecularActivity gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. go-plus.json http://purl.obolibrary.org/obo/GO_0086079 GO:0086078 biolink:MolecularActivity gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. go-plus.json http://purl.obolibrary.org/obo/GO_0086078 GO:0086077 biolink:MolecularActivity gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. go-plus.json gap junction channel activity involved in atrioventricular node cell-bundle of His cell electrical coupling http://purl.obolibrary.org/obo/GO_0086077 GO:0086076 biolink:MolecularActivity gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. go-plus.json gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling|gap junction channel activity involved in atrial cardiomyocyte-atrioventricular node cell electrical coupling http://purl.obolibrary.org/obo/GO_0086076 GO:0086075 biolink:MolecularActivity gap junction channel activity involved in cardiac conduction electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. go-plus.json http://purl.obolibrary.org/obo/GO_0086075 GO:0086074 biolink:BiologicalProcess Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate. go-plus.json http://purl.obolibrary.org/obo/GO_0086074 GO:0086073 biolink:BiologicalProcess bundle of His cell-Purkinje myocyte adhesion involved in cell communication The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate. go-plus.json http://purl.obolibrary.org/obo/GO_0086073 GO:0086072 biolink:BiologicalProcess AV node cell-bundle of His cell adhesion involved in cell communication The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate. go-plus.json atrioventricular node cell-bundle of His cell adhesion involved in cell communication http://purl.obolibrary.org/obo/GO_0086072 GO:0086071 biolink:BiologicalProcess atrial cardiac muscle cell-AV node cell adhesion involved in cell communication The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate. go-plus.json atrial cardiomyocyte-atrioventricular node cell adhesion involved in cell communication|atrial cardiomyocyte-AV node cell adhesion involved in cell communication http://purl.obolibrary.org/obo/GO_0086071 GO:0086070 biolink:BiologicalProcess SA node cell to atrial cardiac muscle cell communication The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json sinoatrial node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiomyocyte to atrial cardiomyocyte communication|sinus node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiac muscle cell to atrial cardiac muscle cell communication|SAN cardiomyocyte to atrial cardiomyocyte communication http://purl.obolibrary.org/obo/GO_0086070 CHEBI:29806 biolink:ChemicalSubstance fumarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29806 chebi_ph7_3 CHEBI:29805 biolink:ChemicalSubstance glycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29805 chebi_ph7_3 BSPO:0015101 biolink:OntologyClass in_dorsal_side_of BSPO:0015101 go-plus.json http://purl.obolibrary.org/obo/BSPO_0015101 GO:0086069 biolink:BiologicalProcess bundle of His cell to Purkinje myocyte communication The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json atrioventricular junction myocyte to bundle branch myocyte|bundle of His cardiac muscle cell to Purkinje myocyte communication|ventricular conduction system cell to cell communication|bundle of His myocyte to atrioventricular junction myocyte|bundle branch myocyte to Purkinje myocyte communication http://purl.obolibrary.org/obo/GO_0086069 BSPO:0015102 biolink:OntologyClass in_ventral_side_of BSPO:0015102 go-plus.json http://purl.obolibrary.org/obo/BSPO_0015102 GO:0086068 biolink:BiologicalProcess Purkinje myocyte to ventricular cardiac muscle cell communication The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0086068 GO:0086067 biolink:BiologicalProcess AV node cell to bundle of His cell communication The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json atrioventricular node cell to bundle of His cell communication http://purl.obolibrary.org/obo/GO_0086067 GO:0086066 biolink:BiologicalProcess atrial cardiac muscle cell to AV node cell communication The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json atrial cardiomyocyte to atrioventricular node cell communication|atrial cardiomyocyte to AV node cell communication http://purl.obolibrary.org/obo/GO_0086066 GO:0086065 biolink:BiologicalProcess cell communication involved in cardiac conduction Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. go-plus.json http://purl.obolibrary.org/obo/GO_0086065 GO:0086064 biolink:BiologicalProcess cell communication by electrical coupling involved in cardiac conduction The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction. go-plus.json http://purl.obolibrary.org/obo/GO_0086064 GO:0086063 biolink:MolecularActivity voltage-gated sodium channel activity involved in SA node cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated sodium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SA node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SAN cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086063 GO:0086062 biolink:MolecularActivity voltage-gated sodium channel activity involved in Purkinje myocyte action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086062 GO:0086061 biolink:MolecularActivity voltage-gated sodium channel activity involved in bundle of His cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086061 GO:0086060 biolink:MolecularActivity voltage-gated sodium channel activity involved in AV node cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086060 CHEBI:29807 biolink:ChemicalSubstance glycyrrhizinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29807 chebi_ph7_3 CHEBI:146293 biolink:ChemicalSubstance 9-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146293 chebi_ph7_3 CHEBI:146296 biolink:ChemicalSubstance N-acetyl-D-leucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_146296 CHEBI:8638 biolink:ChemicalSubstance (9Z,11E,13Z)-octadecatrienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_8638 GO:0086099 biolink:BiologicalProcess phospholipase C-activating angiotensin-activated signaling pathway involved in heart process An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores. go-plus.json phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process|angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process|PLC-activating angiotensin receptor signaling pathway involved in heart process|cardiac angiotensin receptor signaling pathway via activation of PLC|Gq-coupled angiotensin receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086099 GO:0086098 biolink:BiologicalProcess angiotensin-activated signaling pathway involved in heart process An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart. go-plus.json angiotensin-mediated signaling pathway involved in heart process|angiotensin receptor signalling pathway involved in heart process|angiotensin receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086098 GO:0086097 biolink:BiologicalProcess phospholipase C-activating angiotensin-activated signaling pathway An angiotensin-mediated signaling pathway where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores. go-plus.json phospholipase C-activating angiotensin receptor signaling pathway|Gq-coupled angiotensin receptor signaling pathway|phospholipase C-activating angiotensin-mediated signaling pathway|angiotensin-mediated signaling pathway via activation of phospholipase C|PLC-activating angiotensin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0086097 GO:0086096 biolink:BiologicalProcess adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity. go-plus.json cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity|Gi-coupled Beta2-AR signaling pathway involved in heart process|Gi-coupled adrenergic receptor signaling pathway involved in heart process|G-inhibitory-coupled Beta2AR signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086096 GO:0086095 biolink:BiologicalProcess positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate. go-plus.json muscarinic receptor signaling pathway involved in activation of IKACH|Gbeta/gamma-coupled muscarinic receptor signaling pathway involved in negative regulation of heart rate|positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling|muscarinic receptor signaling pathway involved in ion channel activation|cardiac muscarinic receptor signaling via Gbeta/gamma http://purl.obolibrary.org/obo/GO_0086095 CHEBI:8630 biolink:ChemicalSubstance pterostilbene go-plus.json http://purl.obolibrary.org/obo/CHEBI_8630 chebi_ph7_3 GO:0086094 biolink:BiologicalProcess positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction. go-plus.json adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction via ryanodine receptor phosphorylation http://purl.obolibrary.org/obo/GO_0086094 GO:0086093 biolink:BiologicalProcess G protein-coupled acetylcholine receptor signaling pathway involved in heart process A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart. go-plus.json M2 receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signalling pathway involved in heart process|muscarinic receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086093 GO:0086092 biolink:BiologicalProcess regulation of the force of heart contraction by cardiac conduction A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled. go-plus.json http://purl.obolibrary.org/obo/GO_0086092 GO:0086091 biolink:BiologicalProcess regulation of heart rate by cardiac conduction A cardiac conduction process that modulates the frequency or rate of heart contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0086091 GO:0086090 biolink:MolecularActivity voltage-gated potassium channel activity involved in SA node cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated potassium channel activity involved in sinoatrial node cell action potential|voltage-gated potassium channel activity involved in SAN cell action potential|voltage-gated potassium channel activity involved in sinus node cell action potential http://purl.obolibrary.org/obo/GO_0086090 CHEBI:146289 biolink:ChemicalSubstance 9-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146289 chebi_ph7_3 CHEBI:146281 biolink:ChemicalSubstance anthracenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_146281 CHEBI:146288 biolink:ChemicalSubstance 8-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146288 chebi_ph7_3 GO:0086089 biolink:MolecularActivity voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization http://purl.obolibrary.org/obo/GO_0086089 GO:0086088 biolink:MolecularActivity voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086088 GO:0086087 biolink:MolecularActivity voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086087 GO:0086086 biolink:MolecularActivity voltage-gated potassium channel activity involved in AV node cell action potential repolarization Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization http://purl.obolibrary.org/obo/GO_0086086 CHEBI:146291 biolink:ChemicalSubstance 11-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146291 chebi_ph7_3 GO:0086085 biolink:MolecularActivity cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells. go-plus.json cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication http://purl.obolibrary.org/obo/GO_0086085 CHEBI:146290 biolink:ChemicalSubstance 9(S)-HPETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_146290 chebi_ph7_3 GO:0086084 biolink:MolecularActivity cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells. go-plus.json http://purl.obolibrary.org/obo/GO_0086084 GO:0086083 biolink:MolecularActivity cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells. go-plus.json http://purl.obolibrary.org/obo/GO_0086083 GO:0086082 biolink:MolecularActivity cell adhesive protein binding involved in AV node cell-bundle of His cell communication Binding to a protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells. go-plus.json cell adhesive protein binding involved in atrioventricular node cell-bundle of His cell communication http://purl.obolibrary.org/obo/GO_0086082 GO:0086081 biolink:MolecularActivity cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells. go-plus.json cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication|cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication http://purl.obolibrary.org/obo/GO_0086081 GO:0086080 biolink:MolecularActivity protein binding involved in heterotypic cell-cell adhesion Binding to a protein or protein complex contributing to the adhesion of two different types of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0086080 NCBITaxon:1890422 biolink:OrganismalEntity Gloeobacteraceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1890422 CHEBI:78804 biolink:ChemicalSubstance Caenorhabditis elegans metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_78804 CHEBI:78803 biolink:ChemicalSubstance nematode metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_78803 NCBITaxon:1890424 biolink:OrganismalEntity Synechococcales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1890424 CHEBI:78802 biolink:ChemicalSubstance diarylheptanoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78802 CHEBI:78808 biolink:ChemicalSubstance (9Z)-hexacosenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78808 chebi_ph7_3 CHEBI:146270 biolink:ChemicalSubstance oneirogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_146270 CHEBI:78809 biolink:ChemicalSubstance N(6)-octanoyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78809 chebi_ph7_3 NCBITaxon:1890428 biolink:OrganismalEntity Merismopediaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1890428 CHEBI:8614 biolink:ChemicalSubstance psilocybin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8614 CHEBI:8613 biolink:ChemicalSubstance psilocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8613 CHEBI:78815 biolink:ChemicalSubstance N(6)-(S(8)-acetyldihydrolipoyl)-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78815 CHEBI:78814 biolink:ChemicalSubstance 1-oleoyl-2-myristoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78814 chebi_ph7_3 CHEBI:78813 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78813 chebi_ph7_3 CHEBI:78812 biolink:ChemicalSubstance ascr#2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_78812 chebi_ph7_3 CHEBI:78818 biolink:ChemicalSubstance O-(S-3-oxopentanoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78818 chebi_ph7_3 CHEBI:78817 biolink:ChemicalSubstance (5R)-5-hydroxyhexan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_78817 chebi_ph7_3 CHEBI:78816 biolink:ChemicalSubstance 5-hydroxyhexan-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_78816 chebi_ph7_3 NCBITaxon:171637 biolink:OrganismalEntity Amygdaloideae go-plus.json Maloideae|Spiraeoideae http://purl.obolibrary.org/obo/NCBITaxon_171637 CHEBI:78811 biolink:ChemicalSubstance heptanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78811 chebi_ph7_3 CHEBI:78810 biolink:ChemicalSubstance 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78810 chebi_ph7_3 GO:0052689 biolink:MolecularActivity carboxylic ester hydrolase activity Catalysis of the hydrolysis of a carboxylic ester bond. RHEA:21164|Reactome:R-HSA-5693691|Reactome:R-HSA-8937442|EC:3.1.1.1|MetaCyc:CARBOXYLESTERASE-RXN|Reactome:R-HSA-9619024|UM-BBD_reactionID:r1025|KEGG_REACTION:R00630 go-plus.json carboxyl ester hydrolase activity|carboxylic acid esterase activity|carboxylesterase activity|vitamin A esterase|carboxylate esterase activity|carboxylic esterase activity|carboxylic ester hydrolase activity|cocaine esterase activity|procaine esterase activity|carboxyesterase activity|esterase B|esterase A|ali-esterase activity|triacetin esterase|serine esterase activity|B-esterase activity|nonspecific carboxylesterase activity|alpha-carboxylesterase activity http://purl.obolibrary.org/obo/GO_0052689 goslim_drosophila GO:0003711 biolink:MolecularActivity transcription elongation regulator activity A molecular function that regulates transcriptional elongation by enabling the transition from transcription initiation to elongation or by altering the elongation properties of the enzyme during the elongation phase of transcription. go-plus.json transcriptional elongation regulator activity|transcription elongation regulator activity|transcription elongation factor activity http://purl.obolibrary.org/obo/GO_0003711 CHEBI:88190 biolink:ChemicalSubstance 2-oxido-5-methylquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_88190 chebi_ph7_3 GO:0052688 biolink:MolecularActivity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA. KEGG_REACTION:R06515 go-plus.json 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0052688 GO:0003710 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003710 GO:0003713 biolink:MolecularActivity transcription coactivator activity A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. go-plus.json transcription coactivator activity|RNA polymerase II transcription coactivator activity|transcription co-activator activity|RNA polymerase II transcription mediator activity|RNA polymerase II transcription co-activator activity http://purl.obolibrary.org/obo/GO_0003713 GO:0052687 biolink:MolecularActivity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA. KEGG_REACTION:R06396 go-plus.json 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0052687 GO:0003712 biolink:MolecularActivity transcription coregulator activity A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. go-plus.json RNA polymerase II transcriptional cofactor activity|transcription cofactor activity|transcriptional co-regulator http://purl.obolibrary.org/obo/GO_0003712 goslim_drosophila GO:0052686 biolink:MolecularActivity perillic acid-CoA ligase (AMP-forming) activity Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA. KEGG_REACTION:R06368 go-plus.json perillyl-CoA synthetase activity|perillic acid:CoA ligase (AMP-forming) activity http://purl.obolibrary.org/obo/GO_0052686 CHEBI:30889 biolink:ChemicalSubstance L-threo-isocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30889 CHEBI:30887 biolink:ChemicalSubstance isocitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30887 CHEBI:30885 biolink:ChemicalSubstance lupinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30885 GO:1904439 biolink:BiologicalProcess negative regulation of iron ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane. go-plus.json downregulation of ferrous ion import into cell|inhibition of ferrous ion import into cell|down-regulation of ferrous iron import across plasma membrane|down regulation of ferrous ion import into cell|negative regulation of ferrous iron import into cell|downregulation of ferrous iron import across plasma membrane|inhibition of ferrous iron import across plasma membrane|down regulation of ferrous iron import across plasma membrane|negative regulation of ferrous iron import across plasma membrane|negative regulation of ferrous ion import into cell|down-regulation of ferrous ion import into cell http://purl.obolibrary.org/obo/GO_1904439 GO:1904438 biolink:BiologicalProcess regulation of iron ion import across plasma membrane Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane. go-plus.json regulation of ferrous ion import into cell|regulation of ferrous iron import into cell|regulation of ferrous iron import across plasma membrane http://purl.obolibrary.org/obo/GO_1904438 CL:1000979 biolink:Cell ureter smooth muscle cell go-plus.json http://purl.obolibrary.org/obo/CL_1000979 GO:1904437 biolink:BiologicalProcess positive regulation of transferrin receptor binding Any process that activates or increases the frequency, rate or extent of transferrin receptor binding. go-plus.json up-regulation of transferrin receptor binding|activation of transferrin receptor binding|up regulation of transferrin receptor binding|upregulation of transferrin receptor binding http://purl.obolibrary.org/obo/GO_1904437 GO:1904436 biolink:BiologicalProcess negative regulation of transferrin receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding. go-plus.json down-regulation of transferrin receptor binding|downregulation of transferrin receptor binding|down regulation of transferrin receptor binding|inhibition of transferrin receptor binding http://purl.obolibrary.org/obo/GO_1904436 GO:1904435 biolink:BiologicalProcess regulation of transferrin receptor binding Any process that modulates the frequency, rate or extent of transferrin receptor binding. go-plus.json http://purl.obolibrary.org/obo/GO_1904435 GO:0062011 biolink:CellularComponent mitochondrial respiratory chain complex IV pre-assembly complex A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components. go-plus.json COX pre-assemply complex|COX1 preassemply complex http://purl.obolibrary.org/obo/GO_0062011 GO:1904434 biolink:BiologicalProcess positive regulation of ferrous iron binding Any process that activates or increases the frequency, rate or extent of ferrous iron binding. go-plus.json up regulation of ferrous iron binding|upregulation of ferrous iron binding|activation of ferrous iron binding|up-regulation of ferrous iron binding http://purl.obolibrary.org/obo/GO_1904434 GO:0062010 biolink:BiologicalProcess primitive palate development The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0062010 GO:1904433 biolink:BiologicalProcess negative regulation of ferrous iron binding Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding. go-plus.json down-regulation of ferrous iron binding|downregulation of ferrous iron binding|down regulation of ferrous iron binding|inhibition of ferrous iron binding http://purl.obolibrary.org/obo/GO_1904433 GO:0062013 biolink:BiologicalProcess positive regulation of small molecule metabolic process Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. go-plus.json positive regulation of small molecule metabolism http://purl.obolibrary.org/obo/GO_0062013 GO:1904432 biolink:BiologicalProcess regulation of ferrous iron binding Any process that modulates the frequency, rate or extent of ferrous iron binding. go-plus.json http://purl.obolibrary.org/obo/GO_1904432 GO:0062012 biolink:BiologicalProcess regulation of small molecule metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process. go-plus.json regulation of small molecule metabolism http://purl.obolibrary.org/obo/GO_0062012 GO:1904442 biolink:BiologicalProcess negative regulation of thyroid gland epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation. go-plus.json inhibition of Hurthle cell proliferation|negative regulation of thyroid follicular cell proliferation|down-regulation of thyroid follicular cell proliferation|down-regulation of thyroid gland epithelial cell proliferation|negative regulation of Hurthle cell proliferation|down-regulation of Hurthle cell proliferation|inhibition of thyroid gland epithelial cell proliferation|inhibition of thyroid follicular cell proliferation|downregulation of Hurthle cell proliferation|down regulation of thyroid follicular cell proliferation|down regulation of Hurthle cell proliferation|down regulation of thyroid gland epithelial cell proliferation|downregulation of thyroid follicular cell proliferation|downregulation of thyroid gland epithelial cell proliferation http://purl.obolibrary.org/obo/GO_1904442 GO:1904441 biolink:BiologicalProcess regulation of thyroid gland epithelial cell proliferation Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation. go-plus.json regulation of Hurthle cell proliferation|regulation of thyroid follicular cell proliferation http://purl.obolibrary.org/obo/GO_1904441 GO:0062014 biolink:BiologicalProcess negative regulation of small molecule metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. go-plus.json negative regulation of small molecule metabolism http://purl.obolibrary.org/obo/GO_0062014 GO:1904440 biolink:BiologicalProcess positive regulation of iron ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane. go-plus.json positive regulation of ferrous iron import across plasma membrane|activation of ferrous iron import across plasma membrane|positive regulation of ferrous ion import into cell|up-regulation of ferrous iron import across plasma membrane|up regulation of ferrous ion import into cell|positive regulation of ferrous iron import into cell|upregulation of ferrous ion import into cell|up regulation of ferrous iron import across plasma membrane|activation of ferrous ion import into cell|up-regulation of ferrous ion import into cell|upregulation of ferrous iron import across plasma membrane http://purl.obolibrary.org/obo/GO_1904440 CHEBI:39215 biolink:ChemicalSubstance antibiotic pesticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39215 GO:0052681 biolink:MolecularActivity alpha-bisabolene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate. KEGG_REACTION:R08370|EC:4.2.3.38|MetaCyc:RXN-8550|RHEA:25436 go-plus.json (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming] activity|bisabolene synthase activity http://purl.obolibrary.org/obo/GO_0052681 GO:0003719 biolink:MolecularActivity obsolete transcription factor binding, cytoplasmic sequestering OBSOLETE. (Was not defined before being made obsolete). go-plus.json transcription factor binding, cytoplasmic sequestering http://purl.obolibrary.org/obo/GO_0003719 CHEBI:15243 biolink:ChemicalSubstance threonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15243 GO:0052680 biolink:MolecularActivity epi-isozizaene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate. MetaCyc:RXN-9349|EC:4.2.3.37|KEGG_REACTION:R07830|RHEA:25992 go-plus.json (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming] activity http://purl.obolibrary.org/obo/GO_0052680 GO:0003718 biolink:MolecularActivity obsolete RNA polymerase III transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase III. go-plus.json Pol III transcription termination factor activity|RNA polymerase III transcription termination factor activity http://purl.obolibrary.org/obo/GO_0003718 CHEBI:30882 biolink:ChemicalSubstance 2-oxoglutaramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30882 CHEBI:15245 biolink:ChemicalSubstance thymidine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15245 CHEBI:30881 biolink:ChemicalSubstance xanthine-8-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30881 GO:0052685 biolink:MolecularActivity perillic acid-CoA ligase (ADP-forming) activity Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA. EC:6.2.1.-|KEGG_REACTION:R06367 go-plus.json perillic acid:CoA ligase (ADP-forming) activity|perillyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0052685 GO:0003715 biolink:MolecularActivity obsolete transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription. go-plus.json transcription termination factor activity|transcriptional termination factor activity http://purl.obolibrary.org/obo/GO_0003715 GO:0003714 biolink:MolecularActivity transcription corepressor activity A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. go-plus.json transcription corepressor activity|RNA polymerase II transcription corepressor activity|transcription co-repressor activity|RNA polymerase II transcription co-repressor activity http://purl.obolibrary.org/obo/GO_0003714 GO:0052684 biolink:MolecularActivity L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O. EC:4.2.1.122|MetaCyc:RXN0-2382|KEGG_REACTION:R00674|RHEA:26434 go-plus.json tryptophan synthase beta subunit activity|L-serine hydro-lyase (adding indole; L-tryptophan-forming) activity http://purl.obolibrary.org/obo/GO_0052684 GO:0052683 biolink:MolecularActivity (Z)-gamma-bisabolene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate. MetaCyc:RXN-10005|RHEA:26081|EC:4.2.3.40 go-plus.json (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming] activity http://purl.obolibrary.org/obo/GO_0052683 GO:0003717 biolink:MolecularActivity obsolete RNA polymerase II transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase II. go-plus.json RNA polymerase II transcription termination factor activity|Pol II transcription termination factor activity http://purl.obolibrary.org/obo/GO_0003717 GO:0052682 biolink:MolecularActivity epi-cedrol synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate. MetaCyc:RXN-10004|KEGG_REACTION:R09140|EC:4.2.3.39|RHEA:26115 go-plus.json epicedrol synthase activity|(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming) activity|8-epicedrol synthase activity http://purl.obolibrary.org/obo/GO_0052682 GO:0003716 biolink:MolecularActivity obsolete RNA polymerase I transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase I. go-plus.json Pol I transcription termination factor activity|RNA polymerase I transcription termination factor activity http://purl.obolibrary.org/obo/GO_0003716 GO:0003721 biolink:MolecularActivity telomerase RNA reverse transcriptase activity Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template. go-plus.json telomerase, catalyst http://purl.obolibrary.org/obo/GO_0003721 GO:0052699 biolink:BiologicalProcess ergothioneine biosynthetic process The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties. go-plus.json 2-mercaptoergothioneine trimethylbetaine anabolism|2-mercaptoergothioneine trimethylbetaine biosynthesis|ergothioneine biosynthesis|ergothioneine anabolism|2-mercaptoergothioneine trimethylbetaine synthesis|ergothioneine synthesis|2-mercaptoergothioneine trimethylbetaine formation|ergothioneine formation|2-mercaptoergothioneine trimethylbetaine biosynthetic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate biosynthetic process http://purl.obolibrary.org/obo/GO_0052699 GO:0052698 biolink:BiologicalProcess ergothioneine metabolic process The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties. go-plus.json 2-mercaptoergothioneine trimethylbetaine metabolic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate metabolic process|ergothioneine metabolism|2-mercaptoergothioneine trimethylbetaine metabolism http://purl.obolibrary.org/obo/GO_0052698 GO:0003724 biolink:MolecularActivity RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis. MetaCyc:ADENOSINETRIPHOSPHATASE-RXN|Reactome:R-HSA-72647|EC:3.6.4.13 go-plus.json ATP-dependent RNA helicase activity http://purl.obolibrary.org/obo/GO_0003724 GO:0003723 biolink:MolecularActivity RNA binding Binding to an RNA molecule or a portion thereof. Reactome:R-HSA-203922 go-plus.json poly-A RNA binding|poly(A)-RNA binding|base pairing with RNA|poly(A) RNA binding http://purl.obolibrary.org/obo/GO_0003723 goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr GO:0052697 biolink:BiologicalProcess xenobiotic glucuronidation The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion. go-plus.json phase II metabolism http://purl.obolibrary.org/obo/GO_0052697 CHEBI:88184 biolink:ChemicalSubstance metal allergen go-plus.json http://purl.obolibrary.org/obo/CHEBI_88184 GO:0003720 biolink:MolecularActivity telomerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. Reactome:R-HSA-164617|Reactome:R-HSA-163090 go-plus.json http://purl.obolibrary.org/obo/GO_0003720 CHEBI:30897 biolink:ChemicalSubstance L-erythro-isocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30897 chebi_ph7_3 CHEBI:30896 biolink:ChemicalSubstance L-threo-isocitrate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30896 chebi_ph7_3 CHEBI:88188 biolink:ChemicalSubstance drug allergen go-plus.json http://purl.obolibrary.org/obo/CHEBI_88188 GO:1904449 biolink:BiologicalProcess negative regulation of aspartate secretion Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion. go-plus.json down-regulation of aspartate secretion|inhibition of aspartate secretion|down regulation of aspartate secretion|downregulation of aspartate secretion http://purl.obolibrary.org/obo/GO_1904449 CHEBI:88187 biolink:ChemicalSubstance penicillin allergen go-plus.json http://purl.obolibrary.org/obo/CHEBI_88187 GO:1904448 biolink:BiologicalProcess regulation of aspartate secretion Any process that modulates the frequency, rate or extent of aspartate secretion. go-plus.json http://purl.obolibrary.org/obo/GO_1904448 GO:1904447 biolink:BiologicalProcess folate import across plasma membrane The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json folate import into cell|folic acid import across plasma membrane http://purl.obolibrary.org/obo/GO_1904447 GO:1904446 biolink:BiologicalProcess positive regulation of establishment of Sertoli cell barrier Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier. go-plus.json up regulation of establishment of blood-testis barrier|activation of establishment of blood-testis barrier|positive regulation of establishment of SCB|positive regulation of establishment of blood-testis barrier|up regulation of establishment of SCB|positive regulation of establishment of BTB|up regulation of establishment of Sertoli cell barrier|up regulation of establishment of BTB|activation of establishment of Sertoli cell barrier|up-regulation of establishment of blood-testis barrier|upregulation of establishment of SCB|upregulation of establishment of BTB|up-regulation of establishment of Sertoli cell barrier|upregulation of establishment of blood-testis barrier|activation of establishment of SCB|up-regulation of establishment of SCB|up-regulation of establishment of BTB|activation of establishment of BTB|upregulation of establishment of Sertoli cell barrier http://purl.obolibrary.org/obo/GO_1904446 GO:0062000 biolink:BiologicalProcess positive regulation of cardiac endothelial to mesenchymal transition Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition. go-plus.json http://purl.obolibrary.org/obo/GO_0062000 GO:1904445 biolink:BiologicalProcess negative regulation of establishment of Sertoli cell barrier Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier. go-plus.json downregulation of establishment of Sertoli cell barrier|negative regulation of establishment of blood-testis barrier|down-regulation of establishment of blood-testis barrier|downregulation of establishment of SCB|downregulation of establishment of BTB|down regulation of establishment of SCB|down-regulation of establishment of Sertoli cell barrier|inhibition of establishment of blood-testis barrier|inhibition of establishment of SCB|down regulation of establishment of BTB|inhibition of establishment of BTB|inhibition of establishment of Sertoli cell barrier|down regulation of establishment of blood-testis barrier|downregulation of establishment of blood-testis barrier|down-regulation of establishment of SCB|down regulation of establishment of Sertoli cell barrier|negative regulation of establishment of SCB|negative regulation of establishment of BTB|down-regulation of establishment of BTB http://purl.obolibrary.org/obo/GO_1904445 GO:1904444 biolink:BiologicalProcess regulation of establishment of Sertoli cell barrier Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier. go-plus.json regulation of establishment of SCB|regulation of establishment of BTB|regulation of establishment of blood-testis barrier http://purl.obolibrary.org/obo/GO_1904444 GO:0062002 biolink:BiologicalProcess regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. go-plus.json http://purl.obolibrary.org/obo/GO_0062002 GO:1904443 biolink:BiologicalProcess positive regulation of thyroid gland epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation. go-plus.json positive regulation of thyroid follicular cell proliferation|up regulation of thyroid gland epithelial cell proliferation|activation of thyroid gland epithelial cell proliferation|activation of thyroid follicular cell proliferation|up-regulation of Hurthle cell proliferation|activation of Hurthle cell proliferation|up-regulation of thyroid follicular cell proliferation|up-regulation of thyroid gland epithelial cell proliferation|positive regulation of Hurthle cell proliferation|up regulation of Hurthle cell proliferation|upregulation of thyroid follicular cell proliferation|upregulation of thyroid gland epithelial cell proliferation|upregulation of Hurthle cell proliferation|up regulation of thyroid follicular cell proliferation http://purl.obolibrary.org/obo/GO_1904443 GO:0062001 biolink:BiologicalProcess negative regulation of cardiac endothelial to mesenchymal transition Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition. go-plus.json http://purl.obolibrary.org/obo/GO_0062001 GO:1904453 biolink:BiologicalProcess positive regulation of potassium:proton exchanging ATPase activity Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity. go-plus.json up-regulation of hydrogen:potassium exchanging ATPase activity|activation of H,K-ATPase activity|positive regulation of H,K-ATPase activity|positive regulation of gastric H+/K+ ATPase|upregulation of (K+ + H+)-ATPase activity|up-regulation of gastric H(+)/K(+) ATPase activity|up regulation of gastric H+/K+ ATPase|positive regulation of H+/K+-exchanging ATPase activity|positive regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of H+/K+-ATPase activity|up regulation of hydrogen:potassium-exchanging ATPase activity|upregulation of ATP phosphohydrolase (H+/K+-exchanging)|up-regulation of H(+)/K(+)-ATPase activity|up regulation of H(+)/K(+)-exchanging ATPase activity|up regulation of H+/K+-exchanging ATPase activity|upregulation of hydrogen/potassium-exchanging ATPase activity|up-regulation of H+-K+-ATPase activity|activation of hydrogen:potassium-exchanging ATPase activity|upregulation of hydrogen:potassium exchanging ATPase activity|up-regulation of H,K-ATPase activity|upregulation of gastric H(+)/K(+) ATPase activity|up regulation of (K+ + H+)-ATPase activity|upregulation of gastric H+/K+ ATPase|activation of (K+ + H+)-ATPase activity|positive regulation of (K+ + H+)-ATPase activity|upregulation of H(+)/K(+)-ATPase activity|upregulation of H+/K+-ATPase activity|up regulation of ATP phosphohydrolase (H+/K+-exchanging)|upregulation of H(+)/K(+)-exchanging ATPase activity|upregulation of H+-K+-ATPase activity|upregulation of H+/K+-exchanging ATPase activity|up regulation of hydrogen/potassium-exchanging ATPase activity|positive regulation of ATP phosphohydrolase (H+/K+-exchanging)|activation of ATP phosphohydrolase (H+/K+-exchanging)|up regulation of hydrogen:potassium exchanging ATPase activity|positive regulation of hydrogen/potassium-exchanging ATPase activity|activation of hydrogen/potassium-exchanging ATPase activity|up-regulation of hydrogen:potassium-exchanging ATPase activity|upregulation of H,K-ATPase activity|positive regulation of hydrogen:potassium exchanging ATPase activity|activation of hydrogen:potassium exchanging ATPase activity|up regulation of gastric H(+)/K(+) ATPase activity|up-regulation of gastric H+/K+ ATPase|positive regulation of gastric H(+)/K(+) ATPase activity|up-regulation of (K+ + H+)-ATPase activity|positive regulation of hydrogen:potassium-exchanging ATPase activity|up regulation of H+/K+-ATPase activity|up regulation of H(+)/K(+)-ATPase activity|up-regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of H+/K+-exchanging ATPase activity|positive regulation of H+/K+-ATPase activity|activation of H+/K+-exchanging ATPase activity|activation of H(+)/K(+)-ATPase activity|positive regulation of H(+)/K(+)-ATPase activity|up regulation of H+-K+-ATPase activity|activation of H(+)/K(+)-exchanging ATPase activity|activation of H+/K+-ATPase activity|upregulation of hydrogen:potassium-exchanging ATPase activity|activation of gastric H+/K+ ATPase|positive regulation of H+-K+-ATPase activity|activation of H+-K+-ATPase activity|activation of gastric H(+)/K(+) ATPase activity|up-regulation of ATP phosphohydrolase (H+/K+-exchanging)|up regulation of H,K-ATPase activity|up-regulation of hydrogen/potassium-exchanging ATPase activity http://purl.obolibrary.org/obo/GO_1904453 GO:1904452 biolink:BiologicalProcess negative regulation of potassium:proton exchanging ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity. go-plus.json negative regulation of H+/K+-ATPase activity|down-regulation of H(+)/K(+)-ATPase activity|down-regulation of H+/K+-ATPase activity|down regulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of H(+)/K(+)-ATPase activity|inhibition of hydrogen:potassium exchanging ATPase activity|negative regulation of H(+)/K(+)-exchanging ATPase activity|down-regulation of H+-K+-ATPase activity|down-regulation of H(+)/K(+)-exchanging ATPase activity|negative regulation of H+-K+-ATPase activity|down-regulation of H+/K+-exchanging ATPase activity|negative regulation of H+/K+-exchanging ATPase activity|downregulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of H,K-ATPase activity|down-regulation of H,K-ATPase activity|down regulation of (K+ + H+)-ATPase activity|inhibition of H(+)/K(+)-ATPase activity|downregulation of gastric H+/K+ ATPase|inhibition of H+/K+-ATPase activity|inhibition of H+-K+-ATPase activity|inhibition of gastric H(+)/K(+) ATPase activity|down regulation of ATP phosphohydrolase (H+/K+-exchanging)|downregulation of (K+ + H+)-ATPase activity|downregulation of H(+)/K(+)-exchanging ATPase activity|downregulation of H+/K+-exchanging ATPase activity|down regulation of gastric H+/K+ ATPase|down regulation of hydrogen/potassium-exchanging ATPase activity|inhibition of H,K-ATPase activity|down regulation of hydrogen:potassium exchanging ATPase activity|down-regulation of hydrogen:potassium-exchanging ATPase activity|downregulation of ATP phosphohydrolase (H+/K+-exchanging)|down regulation of H+/K+-exchanging ATPase activity|down regulation of H(+)/K(+)-exchanging ATPase activity|downregulation of hydrogen/potassium-exchanging ATPase activity|down regulation of gastric H(+)/K(+) ATPase activity|inhibition of H+/K+-exchanging ATPase activity|downregulation of hydrogen:potassium exchanging ATPase activity|inhibition of H(+)/K(+)-exchanging ATPase activity|inhibition of gastric H+/K+ ATPase|down regulation of H(+)/K(+)-ATPase activity|negative regulation of (K+ + H+)-ATPase activity|down regulation of H+/K+-ATPase activity|down-regulation of (K+ + H+)-ATPase activity|downregulation of gastric H(+)/K(+) ATPase activity|inhibition of hydrogen:potassium-exchanging ATPase activity|down regulation of H+-K+-ATPase activity|downregulation of H+/K+-ATPase activity|downregulation of H(+)/K(+)-ATPase activity|negative regulation of ATP phosphohydrolase (H+/K+-exchanging)|down-regulation of ATP phosphohydrolase (H+/K+-exchanging)|down regulation of H,K-ATPase activity|down-regulation of hydrogen/potassium-exchanging ATPase activity|negative regulation of hydrogen/potassium-exchanging ATPase activity|downregulation of H+-K+-ATPase activity|down-regulation of hydrogen:potassium exchanging ATPase activity|negative regulation of hydrogen:potassium exchanging ATPase activity|inhibition of (K+ + H+)-ATPase activity|downregulation of H,K-ATPase activity|down-regulation of gastric H(+)/K(+) ATPase activity|negative regulation of gastric H(+)/K(+) ATPase activity|inhibition of ATP phosphohydrolase (H+/K+-exchanging)|negative regulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of gastric H+/K+ ATPase|down-regulation of gastric H+/K+ ATPase|inhibition of hydrogen/potassium-exchanging ATPase activity http://purl.obolibrary.org/obo/GO_1904452 GO:0062003 biolink:BiologicalProcess negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. go-plus.json http://purl.obolibrary.org/obo/GO_0062003 GO:1904451 biolink:BiologicalProcess regulation of potassium:proton exchanging ATPase activity Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity. go-plus.json regulation of proton pump activity|regulation of (K+ + H+)-ATPase activity|regulation of gastric H+/K+ ATPase|regulation of ATP phosphohydrolase (H+/K+-exchanging)|regulation of hydrogen/potassium-exchanging ATPase activity|regulation of H+/K+-exchanging ATPase activity|regulation of H(+)/K(+)-exchanging ATPase activity|regulation of hydrogen:potassium exchanging ATPase activity|regulation of gastric H(+)/K(+) ATPase activity|regulation of hydrogen:potassium-exchanging ATPase activity|regulation of H(+)/K(+)-ATPase activity|regulation of H+/K+-ATPase activity|regulation of H+-K+-ATPase activity|regulation of H,K-ATPase activity http://purl.obolibrary.org/obo/GO_1904451 GO:1904450 biolink:BiologicalProcess positive regulation of aspartate secretion Any process that activates or increases the frequency, rate or extent of aspartate secretion. go-plus.json upregulation of aspartate secretion|up regulation of aspartate secretion|activation of aspartate secretion|up-regulation of aspartate secretion http://purl.obolibrary.org/obo/GO_1904450 CHEBI:39226 biolink:ChemicalSubstance chlorocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_39226 GO:0062009 biolink:BiologicalProcess secondary palate development The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. go-plus.json http://purl.obolibrary.org/obo/GO_0062009 CHEBI:15237 biolink:ChemicalSubstance thiomorpholine-3-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15237 GO:0052692 biolink:MolecularActivity raffinose alpha-galactosidase activity Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose. EC:3.2.1.22|KEGG_REACTION:R01103|MetaCyc:RXN-11502 go-plus.json alkaline alpha-galactosidase activity|raffinose galactohydrolase activity|raffinose-specific alkaline alpha-galactosidase activity http://purl.obolibrary.org/obo/GO_0052692 GO:0052691 biolink:MolecularActivity UDP-arabinopyranose mutase activity Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose. RHEA:28350|EC:5.4.99.30|MetaCyc:RXN-11552 go-plus.json UDP-L-arabinopyranose furanomutase activity|uridine-diphosphate-L-arabinose mutase activity|UDP-L-Ara mutase activity|UDP-arabinopyranose pyranomutase activity|UDP-L-arabinose mutase activity http://purl.obolibrary.org/obo/GO_0052691 GO:0003729 biolink:MolecularActivity mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. go-plus.json base pairing with mRNA http://purl.obolibrary.org/obo/GO_0003729 goslim_generic|goslim_chembl|goslim_yeast GO:0052690 biolink:MolecularActivity trichloro-p-hydroquinone reductive dehalogenase activity Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl. UM-BBD_reactionID:r0315|RHEA:56832 go-plus.json tetrachlorohydroquinone reductive dehalogenase activity|trichlorohydroquinone reductive dehalogenase activity|xenobiotic reductase activity|pentaerythritol tetranitrate reductase activity http://purl.obolibrary.org/obo/GO_0052690 GO:0003726 biolink:MolecularActivity double-stranded RNA adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule. Reactome:R-HSA-77615|Reactome:R-HSA-77614 go-plus.json double-stranded RNA specific editase activity http://purl.obolibrary.org/obo/GO_0003726 GO:0052696 biolink:BiologicalProcess flavonoid glucuronidation The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor. go-plus.json flavonoid glucuronoside biosynthesis|flavonoid glucuronoside biosynthetic process|flavonoid glucuronide biosynthesis|flavonoid glucuronide biosynthetic process http://purl.obolibrary.org/obo/GO_0052696 GO:0003725 biolink:MolecularActivity double-stranded RNA binding Binding to double-stranded RNA. go-plus.json dsRNA binding http://purl.obolibrary.org/obo/GO_0003725 GO:0052695 biolink:BiologicalProcess cellular glucuronidation The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor. go-plus.json cellular glucuronoside biosynthesis|cellular glucuronoside biosynthetic process|cellular glucuronide biosynthetic process|cellular glucuronide biosynthesis http://purl.obolibrary.org/obo/GO_0052695 GO:0003728 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003728 GO:0052694 biolink:MolecularActivity jasmonoyl-isoleucine-12-hydroxylase activity Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O. MetaCyc:RXN-12421|RHEA:54808 go-plus.json http://purl.obolibrary.org/obo/GO_0052694 GO:0052693 biolink:MolecularActivity epoxyqueuosine reductase activity Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant. RHEA:32159|EC:1.17.99.6 go-plus.json http://purl.obolibrary.org/obo/GO_0052693 GO:0003727 biolink:MolecularActivity single-stranded RNA binding Binding to single-stranded RNA. go-plus.json ssRNA binding http://purl.obolibrary.org/obo/GO_0003727 CHEBI:30867 biolink:ChemicalSubstance dihydroorotate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30867 chebi_ph7_3 CHEBI:30866 biolink:ChemicalSubstance (R)-dihydroorotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30866 CHEBI:30865 biolink:ChemicalSubstance dihydroorotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30865 CHEBI:30864 biolink:ChemicalSubstance (S)-dihydroorotate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30864 chebi_ph7_3 GO:0062031 biolink:BiologicalProcess filamentous growth MAPK cascade The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth. go-plus.json http://purl.obolibrary.org/obo/GO_0062031 GO:1904459 biolink:BiologicalProcess negative regulation of substance P secretion Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion. go-plus.json down-regulation of substance P secretion|inhibition of substance P secretion|down regulation of substance P secretion|downregulation of substance P secretion http://purl.obolibrary.org/obo/GO_1904459 GO:0062030 biolink:BiologicalProcess negative regulation of stress granule assembly Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. go-plus.json http://purl.obolibrary.org/obo/GO_0062030 GO:1904458 biolink:BiologicalProcess regulation of substance P secretion Any process that modulates the frequency, rate or extent of substance P secretion. go-plus.json http://purl.obolibrary.org/obo/GO_1904458 GO:1904457 biolink:BiologicalProcess positive regulation of neuronal action potential Any process that activates or increases the frequency, rate or extent of neuronal action potential. go-plus.json activation of neuronal action potential|up-regulation of generation of action potential|up-regulation of neuronal action potential|activation of generation of action potential|positive regulation of generation of action potential|up regulation of generation of action potential|upregulation of neuronal action potential|upregulation of generation of action potential|up regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_1904457 GO:0062033 biolink:BiologicalProcess positive regulation of mitotic sister chromatid segregation Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0062033 GO:0062032 biolink:BiologicalProcess cichorine biosynthetic process The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi. go-plus.json cichorine formation|cichorine biosynthesis|cichorine anabolism|cichorine synthesis http://purl.obolibrary.org/obo/GO_0062032 GO:1904456 biolink:BiologicalProcess negative regulation of neuronal action potential Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential. go-plus.json inhibition of generation of action potential|down-regulation of neuronal action potential|inhibition of neuronal action potential|down-regulation of generation of action potential|negative regulation of generation of action potential|downregulation of generation of action potential|down regulation of neuronal action potential|down regulation of generation of action potential|downregulation of neuronal action potential http://purl.obolibrary.org/obo/GO_1904456 GO:0062035 biolink:BiologicalProcess sensory perception of cold stimulus The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. go-plus.json http://purl.obolibrary.org/obo/GO_0062035 GO:1904455 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904455 GO:1904454 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904454 GO:0062034 biolink:BiologicalProcess L-pipecolic acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine. go-plus.json L-pipecolate biosynthetic process http://purl.obolibrary.org/obo/GO_0062034 GO:0062037 biolink:MolecularActivity D-loop DNA binding Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind. go-plus.json DNA displacement loop binding http://purl.obolibrary.org/obo/GO_0062037 GO:1904464 biolink:BiologicalProcess regulation of matrix metallopeptidase secretion Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion. go-plus.json regulation of MMP secretion|regulation of matrix metalloproteinase secretion http://purl.obolibrary.org/obo/GO_1904464 GO:1904463 biolink:BiologicalProcess ergosteryl 3-beta-D-glucoside biosynthetic process The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside. go-plus.json ergosteryl 3-beta-D-glucoside synthesis|ergosteryl 3-beta-D-glucoside formation|ergosteryl 3-beta-D-glucoside biosynthesis|ergosteryl 3-beta-D-glucoside anabolism http://purl.obolibrary.org/obo/GO_1904463 GO:0062036 biolink:BiologicalProcess sensory perception of hot stimulus The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. go-plus.json http://purl.obolibrary.org/obo/GO_0062036 GO:1904462 biolink:BiologicalProcess ergosteryl 3-beta-D-glucoside catabolic process The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside. go-plus.json ergosteryl 3-beta-D-glucoside catabolism|ergosteryl 3-beta-D-glucoside degradation|ergosteryl 3-beta-D-glucoside breakdown http://purl.obolibrary.org/obo/GO_1904462 GO:0062039 biolink:CellularComponent biofilm matrix A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells. go-plus.json http://purl.obolibrary.org/obo/GO_0062039 GO:0062038 biolink:BiologicalProcess positive regulation of pheromone response MAPK cascade Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0062038 GO:1904461 biolink:BiologicalProcess ergosteryl 3-beta-D-glucoside metabolic process The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside. go-plus.json ergosteryl 3-beta-D-glucoside metabolism http://purl.obolibrary.org/obo/GO_1904461 GO:1904460 biolink:BiologicalProcess positive regulation of substance P secretion Any process that activates or increases the frequency, rate or extent of substance P secretion. go-plus.json up regulation of substance P secretion|activation of substance P secretion|up-regulation of substance P secretion|upregulation of substance P secretion http://purl.obolibrary.org/obo/GO_1904460 CHEBI:30861 biolink:ChemicalSubstance methylmalonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30861 CHEBI:30860 biolink:ChemicalSubstance methylmalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30860 CHEBI:15266 biolink:ChemicalSubstance triphosphate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_15266 CHEBI:8653 biolink:ChemicalSubstance pyocyanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_8653 GO:0003700 biolink:MolecularActivity DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. go-plus.json bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding|transcription factor activity|transcription factor activity, metal ion regulated sequence-specific DNA binding|bacterial-type DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|metal ion regulated sequence-specific DNA binding transcription factor activity|gene-specific transcription factor activity|nucleic acid binding transcription factor activity|bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|DNA binding transcription factor activity|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|sequence-specific DNA binding transcription factor activity http://purl.obolibrary.org/obo/GO_0003700 goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida GO:0003702 biolink:MolecularActivity obsolete RNA polymerase II transcription factor activity OBSOLETE. Functions to initiate or regulate RNA polymerase II transcription. go-plus.json RNA polymerase II transcription factor activity http://purl.obolibrary.org/obo/GO_0003702 CHEBI:30879 biolink:ChemicalSubstance alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_30879 chebi_ph7_3 GO:0003701 biolink:MolecularActivity obsolete RNA polymerase I transcription factor activity OBSOLETE. Functions to initiate or regulate RNA polymerase I transcription. go-plus.json RNA polymerase I transcription factor activity http://purl.obolibrary.org/obo/GO_0003701 CHEBI:29888 biolink:ChemicalSubstance diphosphoric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29888 NCBITaxon:3312 biolink:OrganismalEntity Coniferophyta go-plus.json conifers http://purl.obolibrary.org/obo/NCBITaxon_3312 GO:1904469 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904469 GO:0062022 biolink:BiologicalProcess mitotic cohesin ssDNA (lagging strand) loading The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle. go-plus.json second-DNA capture http://purl.obolibrary.org/obo/GO_0062022 GO:1904468 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904468 GO:0062021 biolink:BiologicalProcess mitotic cohesin dsDNA (leading strand) loading The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0062021 GO:1904467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904467 GO:1904466 biolink:BiologicalProcess positive regulation of matrix metallopeptidase secretion Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion. go-plus.json up-regulation of matrix metallopeptidase secretion|upregulation of matrix metalloproteinase secretion|up-regulation of MMP secretion|upregulation of matrix metallopeptidase secretion|up-regulation of matrix metalloproteinase secretion|upregulation of MMP secretion|activation of matrix metalloproteinase secretion|up regulation of matrix metallopeptidase secretion|positive regulation of matrix metalloproteinase secretion|activation of matrix metallopeptidase secretion|up regulation of matrix metalloproteinase secretion|up regulation of MMP secretion|activation of MMP secretion|positive regulation of MMP secretion http://purl.obolibrary.org/obo/GO_1904466 GO:1904465 biolink:BiologicalProcess negative regulation of matrix metallopeptidase secretion Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion. go-plus.json down regulation of matrix metalloproteinase secretion|inhibition of matrix metallopeptidase secretion|inhibition of MMP secretion|inhibition of matrix metalloproteinase secretion|down regulation of matrix metallopeptidase secretion|down regulation of MMP secretion|downregulation of matrix metallopeptidase secretion|down-regulation of matrix metalloproteinase secretion|negative regulation of matrix metalloproteinase secretion|downregulation of MMP secretion|down-regulation of matrix metallopeptidase secretion|downregulation of matrix metalloproteinase secretion|negative regulation of MMP secretion|down-regulation of MMP secretion http://purl.obolibrary.org/obo/GO_1904465 GO:0062023 biolink:CellularComponent collagen-containing extracellular matrix An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. go-plus.json http://purl.obolibrary.org/obo/GO_0062023 GO:1904475 biolink:BiologicalProcess regulation of small GTPase binding Any process that modulates the frequency, rate or extent of small GTPase binding. go-plus.json regulation of Ras GTPase binding http://purl.obolibrary.org/obo/GO_1904475 GO:0062026 biolink:BiologicalProcess negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. go-plus.json http://purl.obolibrary.org/obo/GO_0062026 GO:1904474 biolink:BiologicalProcess cellular response to L-dopa Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904474 GO:0062025 biolink:BiologicalProcess regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. go-plus.json http://purl.obolibrary.org/obo/GO_0062025 CHEBI:39206 biolink:ChemicalSubstance dibenzopyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39206 GO:1904473 biolink:BiologicalProcess response to L-dopa Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904473 GO:0062028 biolink:BiologicalProcess regulation of stress granule assembly Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. go-plus.json http://purl.obolibrary.org/obo/GO_0062028 CHEBI:39205 biolink:ChemicalSubstance dibenzopyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_39205 GO:1904472 biolink:BiologicalProcess positive regulation of endothelin production Any process that activates or increases the frequency, rate or extent of endothelin production. go-plus.json activation of endothelin-3 secretion|activation of endothelin-2 secretion|activation of endothelin-1 secretion|up-regulation of endothelin secretion|positive regulation of endothelin-3 secretion|positive regulation of endothelin-2 secretion|activation of endothelin secretion|up regulation of endothelin-3 secretion|upregulation of EDN3 secretion|positive regulation of endothelin-1 secretion|up regulation of endothelin-2 secretion|upregulation of EDN2 secretion|upregulation of EDN1 secretion|up regulation of endothelin-1 secretion|up-regulation of EDN3 secretion|up-regulation of EDN2 secretion|upregulation of endothelin-3 secretion|upregulation of endothelin-2 secretion|up regulation of endothelin secretion|up-regulation of EDN1 secretion|upregulation of endothelin-1 secretion|activation of EDN3 secretion|activation of EDN2 secretion|activation of EDN1 secretion|up-regulation of endothelin-3 secretion|positive regulation of EDN3 secretion|up-regulation of endothelin-2 secretion|positive regulation of EDN2 secretion|positive regulation of endothelin secretion|upregulation of endothelin secretion|up-regulation of endothelin-1 secretion|positive regulation of EDN1 secretion|up regulation of EDN3 secretion|up regulation of EDN2 secretion|up regulation of EDN1 secretion http://purl.obolibrary.org/obo/GO_1904472 GO:0062027 biolink:BiologicalProcess positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. go-plus.json http://purl.obolibrary.org/obo/GO_0062027 GO:1904471 biolink:BiologicalProcess negative regulation of endothelin production Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production. go-plus.json downregulation of EDN2 secretion|down-regulation of endothelin-3 secretion|negative regulation of endothelin-3 secretion|down-regulation of endothelin-2 secretion|negative regulation of endothelin-2 secretion|downregulation of EDN1 secretion|negative regulation of endothelin-1 secretion|down-regulation of endothelin-1 secretion|down regulation of EDN3 secretion|down regulation of EDN2 secretion|down regulation of EDN1 secretion|downregulation of endothelin-3 secretion|inhibition of EDN3 secretion|downregulation of endothelin-2 secretion|inhibition of EDN2 secretion|downregulation of endothelin-1 secretion|down-regulation of endothelin secretion|inhibition of EDN1 secretion|down regulation of endothelin-3 secretion|down regulation of endothelin-2 secretion|down regulation of endothelin-1 secretion|inhibition of endothelin-3 secretion|downregulation of endothelin secretion|inhibition of endothelin-2 secretion|inhibition of endothelin-1 secretion|negative regulation of EDN3 secretion|down-regulation of EDN3 secretion|negative regulation of EDN2 secretion|down-regulation of EDN2 secretion|negative regulation of endothelin secretion|down-regulation of EDN1 secretion|negative regulation of EDN1 secretion|down regulation of endothelin secretion|inhibition of endothelin secretion|downregulation of EDN3 secretion http://purl.obolibrary.org/obo/GO_1904471 CHEBI:15258 biolink:ChemicalSubstance trichlorophenols go-plus.json http://purl.obolibrary.org/obo/CHEBI_15258 GO:1904470 biolink:BiologicalProcess regulation of endothelin production Any process that modulates the frequency, rate or extent of endothelin production. go-plus.json regulation of EDN3 secretion|regulation of endothelin secretion|regulation of EDN2 secretion|regulation of EDN1 secretion|regulation of endothelin-3 secretion|regulation of endothelin-2 secretion|regulation of endothelin-1 secretion http://purl.obolibrary.org/obo/GO_1904470 GO:0062029 biolink:BiologicalProcess positive regulation of stress granule assembly Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. go-plus.json http://purl.obolibrary.org/obo/GO_0062029 CHEBI:39208 biolink:ChemicalSubstance antibiotic insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39208 GO:0003708 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003708 GO:0003707 biolink:MolecularActivity steroid hormone receptor activity Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function. go-plus.json http://purl.obolibrary.org/obo/GO_0003707 GO:0003709 biolink:MolecularActivity obsolete RNA polymerase III transcription factor activity OBSOLETE. Functions to initiate or regulate RNA polymerase III transcription. go-plus.json RNA polymerase III transcription factor activity http://purl.obolibrary.org/obo/GO_0003709 GO:0003704 biolink:MolecularActivity obsolete specific RNA polymerase II transcription factor activity OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II. go-plus.json specific RNA polymerase II transcription factor activity http://purl.obolibrary.org/obo/GO_0003704 CHEBI:39203 biolink:ChemicalSubstance dibenzopyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_39203 GO:0003703 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003703 GO:0003706 biolink:MolecularActivity obsolete ligand-regulated transcription factor activity OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II in response to a ligand. go-plus.json ligand-regulated transcription factor activity http://purl.obolibrary.org/obo/GO_0003706 CHEBI:39201 biolink:ChemicalSubstance phenazines go-plus.json http://purl.obolibrary.org/obo/CHEBI_39201 GO:0003705 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003705 CHEBI:30848 biolink:ChemicalSubstance urate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30848 CHEBI:30845 biolink:ChemicalSubstance 2-furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30845 CHEBI:30844 biolink:ChemicalSubstance hydroxymalonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30844 CHEBI:30843 biolink:ChemicalSubstance oxomalonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30843 CHEBI:30842 biolink:ChemicalSubstance oxomalonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30842 CHEBI:30841 biolink:ChemicalSubstance 3-hydroxypyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30841 GO:0062051 biolink:CellularComponent lipopolysaccharide transport system A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner. go-plus.json http://purl.obolibrary.org/obo/GO_0062051 CHEBI:29850 biolink:ChemicalSubstance arsonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29850 GO:0062050 biolink:MolecularActivity GPI-mannose ethanolamine phosphate phosphodiesterase activity A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor. go-plus.json http://purl.obolibrary.org/obo/GO_0062050 CHEBI:29852 biolink:ChemicalSubstance methylarsonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29852 GO:0062052 biolink:BiologicalProcess starch granule initiation The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts. go-plus.json http://purl.obolibrary.org/obo/GO_0062052 GO:1904479 biolink:BiologicalProcess negative regulation of intestinal absorption Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption. go-plus.json down regulation of intestinal absorption|downregulation of intestinal absorption|down-regulation of intestinal absorption|inhibition of intestinal absorption http://purl.obolibrary.org/obo/GO_1904479 GO:0086019 biolink:BiologicalProcess cell-cell signaling involved in cardiac conduction Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium. go-plus.json cell-cell signalling involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0086019 GO:0062055 biolink:BiologicalProcess photosynthetic state transition A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems. go-plus.json http://purl.obolibrary.org/obo/GO_0062055 GO:0086018 biolink:BiologicalProcess SA node cell to atrial cardiac muscle cell signaling Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. go-plus.json sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling|SAN cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiac muscle cell to atrial cardiac muscle cell signalling|sinus node cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiomyocyte to atrial cardiomyocyte signalling http://purl.obolibrary.org/obo/GO_0086018 GO:1904478 biolink:BiologicalProcess regulation of intestinal absorption Any process that modulates the frequency, rate or extent of intestinal absorption. go-plus.json http://purl.obolibrary.org/obo/GO_1904478 GO:0062054 biolink:MolecularActivity fluoride channel activity Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0062054 GO:1904477 biolink:BiologicalProcess positive regulation of small GTPase binding Any process that activates or increases the frequency, rate or extent of small GTPase binding. go-plus.json activation of Ras GTPase binding|up-regulation of small GTPase binding|up regulation of small GTPase binding|positive regulation of Ras GTPase binding|upregulation of small GTPase binding http://purl.obolibrary.org/obo/GO_1904477 GO:0062057 biolink:MolecularActivity L-aspartate:fumarate antiporter activity Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out). go-plus.json http://purl.obolibrary.org/obo/GO_0062057 GO:0086017 biolink:BiologicalProcess Purkinje myocyte action potential An action potential that occurs in a Purkinje myocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0086017 GO:1904476 biolink:BiologicalProcess negative regulation of small GTPase binding Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding. go-plus.json inhibition of small GTPase binding|down-regulation of Ras GTPase binding|negative regulation of Ras GTPase binding|downregulation of small GTPase binding|down regulation of small GTPase binding http://purl.obolibrary.org/obo/GO_1904476 GO:0062056 biolink:BiologicalProcess compound eye pigment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia. go-plus.json http://purl.obolibrary.org/obo/GO_0062056 GO:0086016 biolink:BiologicalProcess AV node cell action potential An action potential that occurs in an atrioventricular node cardiac muscle cell. go-plus.json atrioventricular node cardiac muscle cell action potential|AV node cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086016 CHEBI:30849 biolink:ChemicalSubstance L-arabinose go-plus.json http://purl.obolibrary.org/obo/CHEBI_30849 GO:0086015 biolink:BiologicalProcess SA node cell action potential An action potential that occurs in a sinoatrial node cardiac muscle cell. go-plus.json sinus node cardiac muscle cell action potential|SA node cardiac muscle cell action potential|sinoatrial node cardiac muscle cell action potential|SAN cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0086015 GO:1904486 biolink:BiologicalProcess response to 17alpha-ethynylestradiol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904486 GO:0062059 biolink:MolecularActivity FACT complex binding Binding to a FACT complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062059 GO:0086014 biolink:BiologicalProcess atrial cardiac muscle cell action potential An action potential that occurs in an atrial cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0086014 GO:0062058 biolink:MolecularActivity transcription factor TFIIH holo complex binding Binding to a transcription factor TFIIH holo complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062058 GO:1904484 biolink:BiologicalProcess cloacal gland development The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_1904484 GO:0086013 biolink:BiologicalProcess membrane repolarization during cardiac muscle cell action potential The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086013 GO:0086012 biolink:BiologicalProcess membrane depolarization during cardiac muscle cell action potential The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086012 GO:1904483 biolink:MolecularActivity synthetic cannabinoid binding Binding to synthetic cannabinoid. go-plus.json http://purl.obolibrary.org/obo/GO_1904483 CHEBI:15208 biolink:ChemicalSubstance taxuyunnanin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_15208 chebi_ph7_3 GO:0086011 biolink:BiologicalProcess membrane repolarization during action potential The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086011 GO:1904482 biolink:BiologicalProcess cellular response to tetrahydrofolate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904482 GO:0086010 biolink:BiologicalProcess membrane depolarization during action potential The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086010 GO:1904481 biolink:BiologicalProcess response to tetrahydrofolate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904481 GO:1904480 biolink:BiologicalProcess positive regulation of intestinal absorption Any process that activates or increases the frequency, rate or extent of intestinal absorption. go-plus.json up-regulation of intestinal absorption|upregulation of intestinal absorption|up regulation of intestinal absorption|activation of intestinal absorption http://purl.obolibrary.org/obo/GO_1904480 NCBITaxon:3372 biolink:OrganismalEntity Gnetopsida go-plus.json Gneticae|Chlamydospermopsida http://purl.obolibrary.org/obo/NCBITaxon_3372 CHEBI:30859 biolink:ChemicalSubstance 3-maleylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30859 CHEBI:29866 biolink:ChemicalSubstance arsenite(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29866 CHEBI:30854 biolink:ChemicalSubstance indole-3-acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30854 chebi_ph7_3 CHEBI:30853 biolink:ChemicalSubstance glycyrrhetinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30853 NCBITaxon:3378 biolink:OrganismalEntity Gnetales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3378 CHEBI:30852 biolink:ChemicalSubstance galactaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30852 GO:0062040 biolink:CellularComponent fungal biofilm matrix An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses. go-plus.json http://purl.obolibrary.org/obo/GO_0062040 GO:0062042 biolink:BiologicalProcess regulation of cardiac epithelial to mesenchymal transition Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0062042 CHEBI:29864 biolink:ChemicalSubstance mannitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_29864 chebi_ph7_3 GO:0062041 biolink:BiologicalProcess positive regulation of meiotic sister chromatid arm separation Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0062041 GO:0086009 biolink:BiologicalProcess membrane repolarization The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. go-plus.json http://purl.obolibrary.org/obo/GO_0086009 GO:0086008 biolink:MolecularActivity voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086008 GO:0062044 biolink:BiologicalProcess negative regulation of cardiac epithelial to mesenchymal transition Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0062044 GO:1904489 biolink:BiologicalProcess regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter A negative regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process. go-plus.json regulation of ROS metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by downregulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from Pol II promoter|regulation of ROS metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from Pol II promoter|regulation of ROS metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolism by downregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of global transcription from Pol II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by downregulation of global transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904489 GO:0086007 biolink:MolecularActivity voltage-gated calcium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086007 GO:0062043 biolink:BiologicalProcess positive regulation of cardiac epithelial to mesenchymal transition Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. go-plus.json http://purl.obolibrary.org/obo/GO_0062043 GO:1904488 biolink:BiologicalProcess regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter A positive regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process. go-plus.json regulation of ROS metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by up regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by stimulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of global transcription from Pol II promoter|regulation of ROS metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from Pol II promoter|regulation of ROS metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from Pol II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by upregulation of global transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904488 GO:0086006 biolink:MolecularActivity voltage-gated sodium channel activity involved in cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0086006 GO:0062046 biolink:MolecularActivity dehydropipecolic acid reductase Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+. go-plus.json http://purl.obolibrary.org/obo/GO_0062046 GO:1904487 biolink:BiologicalProcess cellular response to 17alpha-ethynylestradiol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904487 GO:0062045 biolink:MolecularActivity L-lysine alpha-aminotransferase Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine. go-plus.json http://purl.obolibrary.org/obo/GO_0062045 GO:0086005 biolink:BiologicalProcess ventricular cardiac muscle cell action potential An action potential that occurs in a ventricular cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0086005 GO:1904497 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1904497 GO:0086004 biolink:BiologicalProcess regulation of cardiac muscle cell contraction Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0086004 GO:0062048 biolink:CellularComponent lymphotoxin complex A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations. go-plus.json lymphotoxin alpha-beta http://purl.obolibrary.org/obo/GO_0062048 GO:0086003 biolink:BiologicalProcess cardiac muscle cell contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0086003 GO:0062047 biolink:MolecularActivity pipecolic acid N-hydroxylase Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O. go-plus.json http://purl.obolibrary.org/obo/GO_0062047 GO:1904496 biolink:BiologicalProcess positive regulation of substance P secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission. go-plus.json up regulation of substance P secretion, neurotransmission|upregulation of substance P secretion, neurotransmission|up-regulation of substance P secretion, neurotransmission|activation of substance P secretion, neurotransmission http://purl.obolibrary.org/obo/GO_1904496 GO:1904495 biolink:BiologicalProcess negative regulation of substance P secretion, neurotransmission Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission. go-plus.json down-regulation of substance P secretion, neurotransmission|downregulation of substance P secretion, neurotransmission|down regulation of substance P secretion, neurotransmission|inhibition of substance P secretion, neurotransmission http://purl.obolibrary.org/obo/GO_1904495 GO:0086002 biolink:BiologicalProcess cardiac muscle cell action potential involved in contraction An action potential that occurs in a cardiac muscle cell and is involved in its contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0086002 GO:1904494 biolink:BiologicalProcess regulation of substance P secretion, neurotransmission Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission. go-plus.json http://purl.obolibrary.org/obo/GO_1904494 GO:0086001 biolink:BiologicalProcess cardiac muscle cell action potential An action potential that occurs in a cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0086001 GO:0062049 biolink:CellularComponent protein phosphatase inhibitor complex A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase. go-plus.json http://purl.obolibrary.org/obo/GO_0062049 GO:1904493 biolink:MolecularActivity tetrahydrofolyl-poly(glutamate) polymer binding Binding to tetrahydrofolyl-poly(glutamate) polymer. go-plus.json http://purl.obolibrary.org/obo/GO_1904493 GO:1904492 biolink:MolecularActivity Ac-Asp-Glu binding Binding to Ac-Asp-Glu. go-plus.json http://purl.obolibrary.org/obo/GO_1904492 GO:1904491 biolink:BiologicalProcess protein localization to ciliary transition zone A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. go-plus.json protein localization in ciliary transition zone|protein localisation in ciliary transition zone|protein localisation to ciliary transition zone http://purl.obolibrary.org/obo/GO_1904491 GO:1904490 biolink:BiologicalProcess negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response. go-plus.json negative regulation of mitochondrial unfolded protein response by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by downregulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by downregulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mitochondrial unfolded protein response by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1904490 CHEBI:30851 biolink:ChemicalSubstance keto-phenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30851 CHEBI:30850 biolink:ChemicalSubstance 3-propylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30850 NCBITaxon:76856 biolink:OrganismalEntity Fusobacterium nucleatum subsp. nucleatum go-plus.json Fusibacterium nucleatum subsp. nucleatum http://purl.obolibrary.org/obo/NCBITaxon_76856 CHEBI:30825 biolink:ChemicalSubstance elaidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30825 chebi_ph7_3 CHEBI:30823 biolink:ChemicalSubstance oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30823 chebi_ph7_3 CHEBI:29838 biolink:ChemicalSubstance disulfanidyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29838 GO:0062071 biolink:CellularComponent Pi Mi complex A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0062071 CHEBI:30820 biolink:ChemicalSubstance 2-oxooctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30820 GO:0062070 biolink:MolecularActivity SAGA complex binding Binding to a SAGA complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062070 OIO:hasDbXref biolink:OntologyClass database_cross_reference go-plus.json http://www.geneontology.org/formats/oboInOwl#hasDbXref GO:0062073 biolink:CellularComponent histone mRNA stem-loop binding complex A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export. go-plus.json SLBP-MIF4GD complex|SLBP-SLIP1 complex http://purl.obolibrary.org/obo/GO_0062073 GO:0062072 biolink:MolecularActivity H3K9me3 modified histone binding Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_0062072 GO:0062075 biolink:BiologicalProcess pollen aperture formation The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0062075 GO:0062074 biolink:CellularComponent pollen aperture An area where exine is reduced or absent, in the pollen wall. go-plus.json http://purl.obolibrary.org/obo/GO_0062074 GO:0062077 biolink:CellularComponent phenylacetyl-CoA 1,2-epoxidase complex A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+). go-plus.json paaABCE complex http://purl.obolibrary.org/obo/GO_0062077 GO:0062076 biolink:MolecularActivity acyl-CoA delta5-desaturase activity Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta5-acyl-CoA + acceptor + 2 H2O. EC:1.14.19.44|RHEA:46424 go-plus.json acyl-CoA delta(5)-desaturase activity|acyl-CoA (8-3)-desaturase|acyl-CoA D5-desaturase activity http://purl.obolibrary.org/obo/GO_0062076 GO:1904499 biolink:BiologicalProcess obsolete regulation of chromatin-mediated maintenance of transcription OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin-mediated maintenance of transcription. go-plus.json http://purl.obolibrary.org/obo/GO_1904499 GO:0086039 biolink:MolecularActivity P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential A calcium-transporting P-type ATPase activity involved in regulation of the plasma membrane potential. go-plus.json calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential http://purl.obolibrary.org/obo/GO_0086039 GO:0062079 biolink:CellularComponent ATG2-ATG18 complex A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0062079 CHEBI:30828 biolink:ChemicalSubstance trans-vaccenate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30828 chebi_ph7_3 GO:0086038 biolink:MolecularActivity calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0086038 GO:1904498 biolink:BiologicalProcess protein localization to mitotic actomyosin contractile ring Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis. go-plus.json protein localization to actomyosin contractile ring involved in mitotic cytokinesis|protein localization to actomyosin contractile ring involved in cytokinesis after mitosis|protein localization to actomyosin contractile ring during mitotic cytokinesis|protein localisation to actomyosin contractile ring involved in cytokinesis after mitosis|protein localization to mitotic actomyosin contractile ring|protein localisation to actomyosin contractile ring involved in mitotic cytokinesis http://purl.obolibrary.org/obo/GO_1904498 GO:0062078 biolink:MolecularActivity TSC1-TSC2 complex binding Binding to a TSC1-TSC2 complex. go-plus.json tuberin sclerosis complex binding|tuberin-hamartin complex binding http://purl.obolibrary.org/obo/GO_0062078 CHEBI:30827 biolink:ChemicalSubstance cis-vaccenate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30827 chebi_ph7_3 GO:0086037 biolink:MolecularActivity P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0086037 GO:0086036 biolink:BiologicalProcess regulation of cardiac muscle cell membrane potential Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0086036 GO:0086033 biolink:BiologicalProcess G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate. go-plus.json G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate|M2 receptor signalling pathway involved in negative regulation of heart rate http://purl.obolibrary.org/obo/GO_0086033 GO:0086030 biolink:BiologicalProcess adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation. go-plus.json adrenergic receptor signaling pathway involved in cardiac muscle relaxation via activation of AC|adrenergic receptor-induced cardiac relaxation|adrenergic receptor signaling pathway involved in cardiac muscle relaxation|Gs-coupled adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation http://purl.obolibrary.org/obo/GO_0086030 CHEBI:15226 biolink:ChemicalSubstance tetrathionate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15226 chebi_ph7_3 CHEBI:8695 biolink:ChemicalSubstance quercetagetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8695 CHEBI:30837 biolink:ChemicalSubstance allantoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30837 CHEBI:29847 biolink:ChemicalSubstance arsonous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29847 chebi_ph7_3 CHEBI:30835 biolink:ChemicalSubstance 2-methylcitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30835 CHEBI:30833 biolink:ChemicalSubstance adipate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30833 CHEBI:30832 biolink:ChemicalSubstance adipic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30832 GO:0062060 biolink:MolecularActivity NuA4 histone acetyltransferase complex binding Binding to a NuA4 histone acetyltransferase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062060 CHEBI:29846 biolink:ChemicalSubstance arsinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29846 chebi_ph7_3 CHEBI:30831 biolink:ChemicalSubstance 2-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30831 CHEBI:30830 biolink:ChemicalSubstance 4-hydroxybutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30830 GO:0062062 biolink:MolecularActivity oligosaccharyltransferase complex binding Binding to an oligosaccharyltransferase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062062 CHEBI:29840 biolink:ChemicalSubstance arsinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29840 GO:0062061 biolink:MolecularActivity TAP complex binding Binding to a TAP complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062061 GO:0062064 biolink:MolecularActivity box C/D snoRNP complex binding Binding to a box C/D snoRNP complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062064 GO:0062063 biolink:MolecularActivity BBSome binding Binding to a BBSome complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062063 GO:0062066 biolink:MolecularActivity PSII associated light-harvesting complex II binding Binding to a PSII associated light-harvesting complex II. go-plus.json http://purl.obolibrary.org/obo/GO_0062066 GO:0062065 biolink:MolecularActivity box H/ACA snoRNP complex binding Binding to a box H/ACA snoRNP complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062065 GO:0086029 biolink:BiologicalProcess Purkinje myocyte to ventricular cardiac muscle cell signaling Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell. go-plus.json Purkinje myocyte to ventricular cardiac muscle cell signalling http://purl.obolibrary.org/obo/GO_0086029 GO:0062068 biolink:MolecularActivity chloroplast photosystem II binding Binding to a chloroplast photosystem II. go-plus.json http://purl.obolibrary.org/obo/GO_0062068 GO:0086028 biolink:BiologicalProcess bundle of His cell to Purkinje myocyte signaling Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte. go-plus.json bundle of His cardiac muscle cell to Purkinje myocyte signalling|bundle of His cardiac muscle cell to Purkinje myocyte signaling http://purl.obolibrary.org/obo/GO_0086028 CHEBI:30839 biolink:ChemicalSubstance orotate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30839 chebi_ph7_3 GO:0062067 biolink:MolecularActivity chloroplast photosystem I binding Binding to a chloroplast photosystem I. go-plus.json http://purl.obolibrary.org/obo/GO_0062067 GO:0086027 biolink:BiologicalProcess AV node cell to bundle of His cell signaling Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. go-plus.json AV node cell to bundle of His cell signalling|atrioventricular node to bundle of His cell signaling http://purl.obolibrary.org/obo/GO_0086027 CHEBI:30838 biolink:ChemicalSubstance itaconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30838 GO:0086026 biolink:BiologicalProcess atrial cardiac muscle cell to AV node cell signaling Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell. go-plus.json atrial cardiomyocyte to atrioventricular node cell signaling|atrial cardiomyocyte to AV node cell signaling|atrial cardiomyocyte to AV node cell signalling http://purl.obolibrary.org/obo/GO_0086026 GO:0062069 biolink:MolecularActivity GARP complex binding Binding to a GARP complex. go-plus.json http://purl.obolibrary.org/obo/GO_0062069 GO:0086024 biolink:BiologicalProcess adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate. go-plus.json Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|adrenergic receptor signaling pathway involved in positive regulation of heart rate|adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|activation of funny current by beta-adrenergic receptor signaling pathway|beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|adrenergic receptor signalling pathway involved in positive regulation of heart rate|If activation by beta-adrenergic receptor signaling pathway http://purl.obolibrary.org/obo/GO_0086024 GO:0086023 biolink:BiologicalProcess adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process A series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart. go-plus.json beta-adrenergic receptor signalling pathway involved in heart process|adrenergic receptor signalling pathway involved in heart process|adrenergic receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086023 GO:0086022 biolink:BiologicalProcess SA node cell-atrial cardiac muscle cell adhesion involved in cell communication The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate. go-plus.json sinoatrial node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SAN cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|sinus node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SA cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SA cardiac muscle cell-atrial cardiac muscle cell adhesion involved in cell communication http://purl.obolibrary.org/obo/GO_0086022 GO:0086021 biolink:BiologicalProcess SA node cell to atrial cardiac muscle cell communication by electrical coupling The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels. go-plus.json SA node cardiac muscle cell to atrial cardiac muscle cell communication by electrical coupling|sinus node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|SA node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|sinoatrial node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|SAN cardiomyocyte to atrial cardiomyocyte communication by electrical coupling http://purl.obolibrary.org/obo/GO_0086021 GO:0086020 biolink:MolecularActivity gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. go-plus.json gap junction channel activity involved in sinus node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in sinoatrial node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SA node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SAN cell-atrial cardiomyocyte electrical coupling http://purl.obolibrary.org/obo/GO_0086020 GO:0003678 biolink:MolecularActivity DNA helicase activity Unwinding of a DNA helix, driven by ATP hydrolysis. Reactome:R-HSA-5693589|EC:3.6.4.12 go-plus.json ATP-dependent DNA helicase activity http://purl.obolibrary.org/obo/GO_0003678 GO:0052601 biolink:MolecularActivity (S)-limonene 1,2-monooxygenase activity Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide. KEGG_REACTION:R09385|KEGG_REACTION:R09389|EC:1.14.13.107|MetaCyc:RXN-9409 go-plus.json (-)-limonene 1,2-monooxygenase activity|(S)-limonene,NAD(P)H:oxygen oxidoreductase activity|(-)-limonene,NAD(P)H:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052601 GO:0003677 biolink:MolecularActivity DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). go-plus.json structure specific DNA binding|microtubule/chromatin interaction|plasmid binding|structure-specific DNA binding http://purl.obolibrary.org/obo/GO_0003677 goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic GO:0052600 biolink:MolecularActivity propane-1,3-diamine oxidase activity Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+. RHEA:30895|EC:1.4.3.22|KEGG_REACTION:R03139|MetaCyc:RXN-6381 go-plus.json trimethylenediamine oxidase activity|1,3-diaminopropane oxidase activity|propane-1,3-diamine:oxygen oxidoreductase (deaminating) activity http://purl.obolibrary.org/obo/GO_0052600 NCBITaxon:339 biolink:OrganismalEntity Xanthomonas campestris go-plus.json Achromobacter lunatus|Pseudomonas campestris|Phytomonas campestris|Bacillus campestris|Xanthomonas campestris var. armoraceae|Xanthomonas campestris var. aberrans|Bacterium campestre http://purl.obolibrary.org/obo/NCBITaxon_339 GO:0003679 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003679 GO:0003674 biolink:MolecularActivity molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process. go-plus.json molecular function http://purl.obolibrary.org/obo/GO_0003674 goslim_chembl|goslim_candida|goslim_yeast|goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic GO:0052605 biolink:MolecularActivity gamma-tocopherol cyclase activity Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol. KEGG_REACTION:R07502|RHEA:37983|MetaCyc:RXN-2543 go-plus.json http://purl.obolibrary.org/obo/GO_0052605 GO:0052604 biolink:MolecularActivity delta-tocopherol cyclase activity Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol. MetaCyc:RXN-2561|RHEA:37987|KEGG_REACTION:R07503 go-plus.json http://purl.obolibrary.org/obo/GO_0052604 GO:0003673 biolink:BiologicalProcess obsolete Gene_Ontology OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes. go-plus.json Gene_Ontology http://purl.obolibrary.org/obo/GO_0003673 GO:0003676 biolink:MolecularActivity nucleic acid binding Binding to a nucleic acid. go-plus.json base pairing http://purl.obolibrary.org/obo/GO_0003676 goslim_chembl|goslim_pir|goslim_plant|goslim_metagenomics GO:0052603 biolink:MolecularActivity 1-chloro-4-nitrosobenzene nitroreductase activity Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O. UM-BBD_enzymeID:e0245|MetaCyc:RXN-8834 go-plus.json http://purl.obolibrary.org/obo/GO_0052603 GO:0003675 biolink:CellularComponent obsolete protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json protein http://purl.obolibrary.org/obo/GO_0003675 GO:0052602 biolink:MolecularActivity 4-chloronitrobenzene nitroreductase activity Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O. UM-BBD_enzymeID:e0245|MetaCyc:RXN-8833 go-plus.json http://purl.obolibrary.org/obo/GO_0052602 GO:0052609 biolink:MolecularActivity 4-ketotorulene 3-hydroxylase activity Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O. MetaCyc:RXN-8218 go-plus.json beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity http://purl.obolibrary.org/obo/GO_0052609 GO:0052608 biolink:MolecularActivity echinenone 3-hydroxylase activity Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O. MetaCyc:RXN-8214 go-plus.json beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity http://purl.obolibrary.org/obo/GO_0052608 GO:0052607 biolink:MolecularActivity 7-hydroxy-chlorophyllide a oxygenase activity Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O. MetaCyc:RXN-7677|RHEA:22136|KEGG_REACTION:R08204 go-plus.json 7-hydroxychlorophyllide-a oxygenase activity|CAO activity|7-hydroxychlorophyllide a:oxygen 7-oxidoreductase activity|chlorophyll b synthetase activity|chlorophyll-b synthase activity http://purl.obolibrary.org/obo/GO_0052607 GO:0052606 biolink:MolecularActivity chlorophyllide a oxygenase activity Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O. MetaCyc:RXN-7676|RHEA:22676|KEGG_REACTION:R08203 go-plus.json chlorophyllide-a oxygenase activity|CAO activity|chlorophyllide a:oxygen 7-oxidoreductase activity|chlorophyll a oxygenase activity http://purl.obolibrary.org/obo/GO_0052606 CHEBI:136969 biolink:ChemicalSubstance 4-hydroxyestrone 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136969 chebi_ph7_3 CHEBI:88112 biolink:ChemicalSubstance 3-oxochola-4,6-dien-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88112 CHEBI:88115 biolink:ChemicalSubstance N(2)-L-glutamino(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_88115 chebi_ph7_3 NCBITaxon:338 biolink:OrganismalEntity Xanthomonas go-plus.json "Phytomonas" Bergey et al. 1923 http://purl.obolibrary.org/obo/NCBITaxon_338 CHEBI:88117 biolink:ChemicalSubstance 2-ethylhexyl sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88117 CHEBI:88119 biolink:ChemicalSubstance dTDP-2,3-dehydro-2,6-dideoxy-4-keto-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88119 chebi_ph7_3 CHEBI:88118 biolink:ChemicalSubstance 2,3-epoxy-2,3-dihydrobenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88118 chebi_ph7_3 CHEBI:136967 biolink:ChemicalSubstance 2-hydroxyestrone 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136967 chebi_ph7_3 CHEBI:136966 biolink:ChemicalSubstance 3beta-hydroxysteroid-4alpha-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_136966 chebi_ph7_3 CHEBI:136965 biolink:ChemicalSubstance lithocholate 3-O-(beta-D-glucuronide)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136965 chebi_ph7_3 CHEBI:78785 biolink:ChemicalSubstance O-(S-2,3-saturated acylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78785 chebi_ph7_3 CHEBI:78784 biolink:ChemicalSubstance O-[S-(2E)-2-enoylpantetheine-4'-phosphoryl]-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78784 chebi_ph7_3 CHEBI:78783 biolink:ChemicalSubstance O-(S-oleoylpantetheine-4'-phosphoryl)serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78783 chebi_ph7_3 CHEBI:39174 biolink:ChemicalSubstance 2-chloropyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39174 chebi_ph7_3 CHEBI:136960 biolink:ChemicalSubstance ditrans,polycis-polyprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136960 chebi_ph7_3 GO:0003689 biolink:MolecularActivity DNA clamp loader activity Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis. Reactome:R-HSA-176264|Reactome:R-HSA-174439 go-plus.json DNA clamp loading ATPase activity|PCNA loading complex activity|protein-DNA loading ATPase activity|DNA-protein loading ATPase activity|PCNA loading activity http://purl.obolibrary.org/obo/GO_0003689 GO:0052612 biolink:MolecularActivity adonirubin 3-hydroxylase activity Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O. MetaCyc:RXN-8187 go-plus.json carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity http://purl.obolibrary.org/obo/GO_0052612 GO:0003688 biolink:MolecularActivity DNA replication origin binding Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. go-plus.json ARS binding http://purl.obolibrary.org/obo/GO_0003688 GO:0052611 biolink:MolecularActivity beta-carotene 3-hydroxylase activity Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O. MetaCyc:RXN-8025|RHEA:30323 go-plus.json carotene beta-ring hydroxylase activity|beta-carotene 3-hydroxylase activity|beta-carotene hydroxylase activity http://purl.obolibrary.org/obo/GO_0052611 GO:0052610 biolink:MolecularActivity beta-cryptoxanthin hydroxylase activity Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O. RHEA:30327|MetaCyc:RXN-8026 go-plus.json carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity http://purl.obolibrary.org/obo/GO_0052610 GO:0052616 biolink:MolecularActivity ent-kaur-16-en-19-ol oxidase activity Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al. EC:1.14.14.86|MetaCyc:RXN-5242|RHEA:21304 go-plus.json http://purl.obolibrary.org/obo/GO_0052616 GO:0003685 biolink:MolecularActivity obsolete DNA repair protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA repair protein http://purl.obolibrary.org/obo/GO_0003685 GO:0052615 biolink:MolecularActivity ent-kaurene oxidase activity Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol. EC:1.14.14.86|RHEA:32323|MetaCyc:1.14.13.78-RXN go-plus.json http://purl.obolibrary.org/obo/GO_0052615 GO:0003684 biolink:MolecularActivity damaged DNA binding Binding to damaged DNA. go-plus.json DNA repair enzyme|DNA repair protein http://purl.obolibrary.org/obo/GO_0003684 GO:0003687 biolink:MolecularActivity obsolete DNA replication factor OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA replication factor http://purl.obolibrary.org/obo/GO_0003687 GO:0052614 biolink:MolecularActivity uracil oxygenase activity Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate. MetaCyc:RXN0-6444|RHEA:31587 go-plus.json pyrimidine oxygenase activity http://purl.obolibrary.org/obo/GO_0052614 CHEBI:39192 biolink:ChemicalSubstance dithiolanes go-plus.json http://purl.obolibrary.org/obo/CHEBI_39192 GO:0003686 biolink:MolecularActivity obsolete DNA repair enzyme OBSOLETE. (Was not defined before being made obsolete). go-plus.json DNA repair enzyme http://purl.obolibrary.org/obo/GO_0003686 GO:0052613 biolink:MolecularActivity canthaxanthin 3-hydroxylase activity Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O. MetaCyc:RXN-8186 go-plus.json carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity http://purl.obolibrary.org/obo/GO_0052613 GO:0003681 biolink:MolecularActivity bent DNA binding Binding to DNA in a bent conformation. go-plus.json http://purl.obolibrary.org/obo/GO_0003681 GO:0003680 biolink:MolecularActivity minor groove of adenine-thymine-rich DNA binding Binding to a DNA structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins. go-plus.json AT binding|AT-rich DNA binding|AT DNA binding http://purl.obolibrary.org/obo/GO_0003680 GO:0052619 biolink:MolecularActivity coenzyme F420-1:gamma-L-glutamate ligase activity Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate. RHEA:30523|EC:6.3.2.34|MetaCyc:RXN-8081 go-plus.json http://purl.obolibrary.org/obo/GO_0052619 GO:0052618 biolink:MolecularActivity coenzyme F420-0:L-glutamate ligase activity Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate. RHEA:30555|EC:6.3.2.31|MetaCyc:RXN-8080 go-plus.json http://purl.obolibrary.org/obo/GO_0052618 GO:0003683 biolink:MolecularActivity obsolete lamin/chromatin binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json lamin/chromatin binding http://purl.obolibrary.org/obo/GO_0003683 CHEBI:88102 biolink:ChemicalSubstance 3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88102 GO:0003682 biolink:MolecularActivity chromatin binding Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. go-plus.json microtubule/chromatin interaction|lamin/chromatin binding|nuclear membrane vesicle binding to chromatin http://purl.obolibrary.org/obo/GO_0003682 goslim_pir|goslim_plant|goslim_drosophila|goslim_chembl|goslim_yeast GO:0052617 biolink:MolecularActivity ent-kaur-16-en-19-al oxidase activity Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate. RHEA:10928|EC:1.14.14.86|MetaCyc:RXN-7580 go-plus.json http://purl.obolibrary.org/obo/GO_0052617 CHEBI:64152 biolink:ChemicalSubstance cysteine protease inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64152 CHEBI:88104 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88104 CHEBI:88105 biolink:ChemicalSubstance 3beta,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88105 CHEBI:136975 biolink:ChemicalSubstance 4-methoxy-17beta-estradiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_136975 chebi_ph7_3 CHEBI:88108 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88108 CHEBI:136974 biolink:ChemicalSubstance 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136974 chebi_ph7_3 CHEBI:88107 biolink:ChemicalSubstance geranyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88107 chebi_ph7_3 CHEBI:136973 biolink:ChemicalSubstance 4-methoxyestrone 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136973 chebi_ph7_3 CHEBI:136972 biolink:ChemicalSubstance 4-methoxyestrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_136972 chebi_ph7_3 CHEBI:88109 biolink:ChemicalSubstance 7alpha-hydroxy-3-oxochol-4-en-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88109 CHEBI:136979 biolink:ChemicalSubstance isowyosine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136979 chebi_ph7_3 NCBITaxon:340 biolink:OrganismalEntity Xanthomonas campestris pv. campestris go-plus.json Xanthomonas campestris campestris|Xanthomonas campestris (pv. campestris) http://purl.obolibrary.org/obo/NCBITaxon_340 CHEBI:136978 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136978 chebi_ph7_3 CHEBI:136977 biolink:ChemicalSubstance 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(ribonucleotide)(3-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136977 chebi_ph7_3 CHEBI:136976 biolink:ChemicalSubstance 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136976 chebi_ph7_3 CHEBI:78796 biolink:ChemicalSubstance nonadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78796 chebi_ph7_3 CHEBI:78795 biolink:ChemicalSubstance pentadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78795 chebi_ph7_3 CHEBI:136971 biolink:ChemicalSubstance 2-methoxyestrone 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136971 chebi_ph7_3 CHEBI:136970 biolink:ChemicalSubstance 4-hydroxyestrone 4-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136970 chebi_ph7_3 CHEBI:78798 biolink:ChemicalSubstance O-[S-(3Z)-decenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78798 chebi_ph7_3 GO:0052623 biolink:MolecularActivity ADP dimethylallyltransferase activity Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate. EC:2.5.1.-|KEGG_REACTION:R08051|MetaCyc:RXN-4305 go-plus.json ADP isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase activity|dimethylallyl-diphosphate:ADP dimethylallyltransferase activity http://purl.obolibrary.org/obo/GO_0052623 GO:0052622 biolink:MolecularActivity ATP dimethylallyltransferase activity Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate. KEGG_REACTION:R08052|EC:2.5.1.-|MetaCyc:RXN-4303 go-plus.json dimethylallyl-diphosphate:ATP dimethylallyltransferase activity|ATP isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase activity http://purl.obolibrary.org/obo/GO_0052622 GO:0052621 biolink:MolecularActivity diguanylate cyclase activity Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+). RHEA:24898|EC:2.7.7.65|KEGG_REACTION:R08057|MetaCyc:RXN0-5359 go-plus.json GTP:GTP guanylyltransferase activity http://purl.obolibrary.org/obo/GO_0052621 GO:0052620 biolink:MolecularActivity thymine dehydrogenase activity Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2. RHEA:13469|MetaCyc:RXN-8646|EC:1.17.99.4 go-plus.json http://purl.obolibrary.org/obo/GO_0052620 CHEBI:39162 biolink:ChemicalSubstance (R)-nicotine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39162 GO:0052627 biolink:MolecularActivity vanillate amino acid synthetase activity Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052627 GO:0052626 biolink:MolecularActivity benzoate amino acid synthetase activity Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate. go-plus.json benzoyl amino acid synthetase activity http://purl.obolibrary.org/obo/GO_0052626 CHEBI:64161 biolink:ChemicalSubstance asperthecin go-plus.json http://purl.obolibrary.org/obo/CHEBI_64161 CHEBI:39161 biolink:ChemicalSubstance 1,1,1-trichloro-2,2-diphenylethane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39161 chebi_ph7_3 GO:0052625 biolink:MolecularActivity 4-aminobenzoate amino acid synthetase activity Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate. go-plus.json p-aminobenzoyl amino acid synthetase activity|p-aminobenzoate amino acid synthetase activity|4-aminobenzoyl amino acid synthetase activity|pABA amino acid synthetase activity http://purl.obolibrary.org/obo/GO_0052625 GO:0052624 biolink:MolecularActivity 2-phytyl-1,4-naphthoquinone methyltransferase activity Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+. KEGG_REACTION:R06859|MetaCyc:RXN-6723|MetaCyc:RXN-7569 go-plus.json SA methyltransferase activity|S-adenosyl-L-methionine:salicylate carboxyl methyltransferase activity|salicylic acid methyltransferase activity|S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinone methyltransferase activity|S-adenosyl-L-methionine:demethylphylloquinone methyltransferase activity|demethylphylloquinone methyltransferase activity|salicylate methyltransferase activity http://purl.obolibrary.org/obo/GO_0052624 CHEBI:88133 biolink:ChemicalSubstance D-ribitol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88133 NCBITaxon:356 biolink:OrganismalEntity Hyphomicrobiales go-plus.json Rhizobiales|alpha-2 proteobacteria|rhizobacteria|Rhizobiaceae group http://purl.obolibrary.org/obo/NCBITaxon_356 GO:0052629 biolink:MolecularActivity phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+. Reactome:R-HSA-6809320|Reactome:R-HSA-1676203|EC:3.1.3.95|RHEA:39019|Reactome:R-HSA-1676065|Reactome:R-HSA-1676105|MetaCyc:RXN-10958|Reactome:R-HSA-6809944|Reactome:R-HSA-6809778 go-plus.json http://purl.obolibrary.org/obo/GO_0052629 CHEBI:88135 biolink:ChemicalSubstance N-acetylmethionine sulfone go-plus.json http://purl.obolibrary.org/obo/CHEBI_88135 GO:0052628 biolink:MolecularActivity 4-hydroxybenzoate amino acid synthetase activity Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate. go-plus.json 4HBA amino acid synthetase activity|4-hydroxybenzoyl amino acid synthetase activity|p-hydroxybenzoyl amino acid synthetase activity|p-hydroxybenzoate amino acid synthetase activity http://purl.obolibrary.org/obo/GO_0052628 CHEBI:88137 biolink:ChemicalSubstance 2-hydro-beta-NADP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88137 chebi_ph7_3 CHEBI:88136 biolink:ChemicalSubstance N-acetyl-L-methionine sulfoximine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88136 CHEBI:88139 biolink:ChemicalSubstance 6-hydro-beta-NADP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88139 chebi_ph7_3 CHEBI:88138 biolink:ChemicalSubstance 2-hydro-beta-NAD(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88138 chebi_ph7_3 CHEBI:39155 biolink:ChemicalSubstance chlorocycloalkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39155 CHEBI:39154 biolink:ChemicalSubstance chlorocyclohexane go-plus.json http://purl.obolibrary.org/obo/CHEBI_39154 CHEBI:39153 biolink:ChemicalSubstance 5-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39153 CHEBI:39159 biolink:ChemicalSubstance (S)-trichostatic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39159 CHEBI:39158 biolink:ChemicalSubstance (R)-trichostatic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39158 CHEBI:39157 biolink:ChemicalSubstance trichostatic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39157 GO:0052634 biolink:MolecularActivity C-19 gibberellin 2-beta-dioxygenase activity Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons. EC:1.14.11.13 go-plus.json C-19 gibberellin 2beta-dioxygenase activity|C-19 gibberellin 2beta-hydroxylase activity|C-19 GA 2-oxidase activity|(C-19 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|C-19 gibberellin 2-oxidase activity|C-19 gibberellin 2-beta-hydroxylase activity|C(19) gibberellin 2-oxidase activity http://purl.obolibrary.org/obo/GO_0052634 GO:0052633 biolink:MolecularActivity isocitrate hydro-lyase (cis-aconitate-forming) activity Catalysis of the reaction: cis-aconitate + H2O = isocitrate. KEGG_REACTION:R01900|MetaCyc:ACONITATEHYDR-RXN|RHEA:22144 go-plus.json citrate hydro-lyase activity|citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|cis-aconitase activity|aconitate hydratase activity|citrate(isocitrate) hydro-lyase activity http://purl.obolibrary.org/obo/GO_0052633 GO:0052632 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052632 GO:0052631 biolink:MolecularActivity sphingolipid delta-8 desaturase activity Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8). MetaCyc:RXN-7798|RHEA:46268 go-plus.json http://purl.obolibrary.org/obo/GO_0052631 GO:0052638 biolink:MolecularActivity indole-3-butyrate beta-glucosyltransferase activity Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP. MetaCyc:RXN-11655|RHEA:62708 go-plus.json UDP-glucose:indol-3-ylbutyrate glucosyltransferase activity|IBA-glucose synthase activity|IBA-Glc synthetase activity|IBAGlu synthase activity|UDPglucose:indole-3-butyrate beta-D-glucosyltransferase activity|UDP-glucose:indol-3-ylbutyrate glucosyl-transferase activity|indol-3-ylbutyrylglucose synthase activity|uridine diphosphoglucose-indolebutyrate glucosyltransferase activity|UDP-glucose:(indol-3-yl)butyrate beta-D-glucosyltransferase activity|indole-3-butyric acid glucosyltransferase activity|UDPG-indol-3-ylbutyryl glucosyl transferase activity http://purl.obolibrary.org/obo/GO_0052638 CHEBI:39173 biolink:ChemicalSubstance chloropyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39173 NCBITaxon:3398 biolink:OrganismalEntity Magnoliopsida go-plus.json Magnoliophyta|Angiospermae|flowering plants|flowering plants|angiosperms http://purl.obolibrary.org/obo/NCBITaxon_3398 GO:0052637 biolink:MolecularActivity delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol. go-plus.json http://purl.obolibrary.org/obo/GO_0052637 CHEBI:39172 biolink:ChemicalSubstance monochloropyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39172 GO:0052636 biolink:MolecularActivity arabinosyltransferase activity Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor). go-plus.json arabinosyl transferase activity http://purl.obolibrary.org/obo/GO_0052636 GO:0052635 biolink:MolecularActivity C-20 gibberellin 2-beta-dioxygenase activity Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons. go-plus.json C-20 gibberellin 2beta-hydroxylase activity|C-20 gibberellin 2-beta-hydroxylase activity|C(20) gibberellin 2-oxidase activity|C-20 gibberellin 2-oxidase activity|C-20 gibberellin 2beta-dioxygenase activity|C-20 GA 2-oxidase activity|(C-20 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating) http://purl.obolibrary.org/obo/GO_0052635 GO:0052639 biolink:MolecularActivity salicylic acid glucosyltransferase (ester-forming) activity Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP. RHEA:62316|MetaCyc:RXN-11659 go-plus.json UDP:glucose:SA glucosyltransferase (ester-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylic acid glucosyltransferase (ester-forming) activity|UDP:glucose:salicylate glucosyltransferase (ester-forming) activity http://purl.obolibrary.org/obo/GO_0052639 CHEBI:88123 biolink:ChemicalSubstance (R)-12-hydroxysqualene go-plus.json http://purl.obolibrary.org/obo/CHEBI_88123 chebi_ph7_3 CHEBI:64178 biolink:ChemicalSubstance (2S)-2-amino-3-oxo-4-(phosphonatooxy)butanoate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64178 CHEBI:39166 biolink:ChemicalSubstance tetramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_39166 GO:0052630 biolink:MolecularActivity UDP-N-acetylgalactosamine diphosphorylase activity Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine. RHEA:34363|EC:2.7.7.83 go-plus.json uridine diphosphoacetylgalactosamine pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-galactose-1-phosphate uridylyltransferase activity|N-acetylgalactosamine 1-phosphate uridylyltransferase|UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase activity|uridine diphosphoacetylgalactosamine phosphorylase activity|N-acetylgalactosamine-1-phosphate uridyltransferase activity|UDP-acetylgalactosamine pyrophosphorylase activity|uridine diphosphate-N-acetylgalactosamine pyrophosphorylase activity|UDP-N-acetylgalactosamine pyrophosphorylase activity|UDP-GalNAc pyrophosphorylase activity http://purl.obolibrary.org/obo/GO_0052630 GO:0052645 biolink:BiologicalProcess F420-0 metabolic process The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues. go-plus.json coenzyme F420-0 metabolic process|coenzyme F420-0 metabolism|F420-0 metabolism|F(420)-0 metabolic process http://purl.obolibrary.org/obo/GO_0052645 CHEBI:64180 biolink:ChemicalSubstance 2-decaprenyl-6-methoxyhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64180 chebi_ph7_3 GO:0052644 biolink:BiologicalProcess chlorophyllide a metabolic process The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a. go-plus.json chlorophyllide a metabolism http://purl.obolibrary.org/obo/GO_0052644 GO:0052643 biolink:BiologicalProcess chlorophyllide metabolic process The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl. go-plus.json chlorophyllide metabolism http://purl.obolibrary.org/obo/GO_0052643 GO:0052642 biolink:MolecularActivity lysophosphatidic acid phosphatase activity Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol. Reactome:R-HSA-8878654 go-plus.json LPA phosphatase activity|lysophosphatidate phosphatase activity http://purl.obolibrary.org/obo/GO_0052642 GO:0052649 biolink:BiologicalProcess coenzyme gamma-F420-2 metabolic process The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid. go-plus.json coenzyme F420 metabolic process|F420-2 metabolism|F420-2 metabolic process|coenzyme gamma-F420-2 metabolism|coenzyme F420 metabolism http://purl.obolibrary.org/obo/GO_0052649 GO:0052648 biolink:BiologicalProcess ribitol phosphate metabolic process The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. go-plus.json ribitol phosphate metabolism http://purl.obolibrary.org/obo/GO_0052648 CHEBI:64183 biolink:ChemicalSubstance ubiquinol-10 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64183 chebi_ph7_3 GO:0052647 biolink:BiologicalProcess pentitol phosphate metabolic process The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule. go-plus.json pentitol phosphate metabolism http://purl.obolibrary.org/obo/GO_0052647 CHEBI:64182 biolink:ChemicalSubstance 3-demethylubiquinol-10 go-plus.json http://purl.obolibrary.org/obo/CHEBI_64182 chebi_ph7_3 CHEBI:88153 biolink:ChemicalSubstance tripropionin go-plus.json http://purl.obolibrary.org/obo/CHEBI_88153 chebi_ph7_3 GO:0052646 biolink:BiologicalProcess alditol phosphate metabolic process The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. go-plus.json alditol phosphate metabolism http://purl.obolibrary.org/obo/GO_0052646 CHEBI:64181 biolink:ChemicalSubstance 2-decaprenyl-6-methoxy-3-methylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_64181 chebi_ph7_3 CHEBI:88152 biolink:ChemicalSubstance 2-O-[alpha-D-mannosyl-(1->2)-alpha-D-glucosyl]-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88152 CHEBI:88155 biolink:ChemicalSubstance dipropionin go-plus.json http://purl.obolibrary.org/obo/CHEBI_88155 chebi_ph7_3 CHEBI:88154 biolink:ChemicalSubstance alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_88154 chebi_ph7_3 CHEBI:88157 biolink:ChemicalSubstance cis-3-hydroxy-D-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_88157 CHEBI:64186 biolink:ChemicalSubstance (2S)-2-amino-3-oxo-4-(phosphonooxy)butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64186 CHEBI:88156 biolink:ChemicalSubstance diacetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_88156 chebi_ph7_3 CHEBI:88159 biolink:ChemicalSubstance 3-hydroxy-O,5-dimethyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88159 CHEBI:88158 biolink:ChemicalSubstance 1,4-naphthoquinone-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88158 NCBITaxon:374 biolink:OrganismalEntity Bradyrhizobium go-plus.json Agromonas http://purl.obolibrary.org/obo/NCBITaxon_374 GO:0052641 biolink:MolecularActivity benzoic acid glucosyltransferase activity Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP. MetaCyc:RXN-11660 go-plus.json UDP:glucose:BA glucosyltransferase activity|UDP:glucose:benzoic acid glucosyltransferase activity|benzoate glucosyltransferase activity|UDP:glucose:benzoate glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0052641 GO:0052640 biolink:MolecularActivity salicylic acid glucosyltransferase (glucoside-forming) activity Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP. MetaCyc:RXN-11658|RHEA:62312 go-plus.json UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity|UDP:glucose:SA glucosyltransferase (glucoside-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity http://purl.obolibrary.org/obo/GO_0052640 GO:0052656 biolink:MolecularActivity L-isoleucine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid. MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN|RHEA:24801|EC:2.6.1.42|KEGG_REACTION:R02199 go-plus.json L-isoleucine aminotransferase activity http://purl.obolibrary.org/obo/GO_0052656 goslim_chembl GO:0052655 biolink:MolecularActivity L-valine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid. MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN|RHEA:24813|KEGG_REACTION:R01214|EC:2.6.1.42 go-plus.json L-valine aminotransferase activity http://purl.obolibrary.org/obo/GO_0052655 goslim_chembl GO:0052654 biolink:MolecularActivity L-leucine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid. MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN|EC:2.6.1.42|KEGG_REACTION:R01090 go-plus.json L-leucine aminotransferase activity http://purl.obolibrary.org/obo/GO_0052654 goslim_chembl GO:0052653 biolink:BiologicalProcess 3',5'-cyclic diguanylic acid metabolic process The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine. go-plus.json 3',5'-cyclic diguanylic acid metabolism|cyclic diguanylate metabolic process|cyclic diguanylate metabolism|cdiGMP metabolism|cdiGMP metabolic process http://purl.obolibrary.org/obo/GO_0052653 CHEBI:88140 biolink:ChemicalSubstance 6-hydro-beta-NAD(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88140 chebi_ph7_3 GO:1904409 biolink:BiologicalProcess regulation of secretory granule organization Any process that modulates the frequency, rate or extent of secretory granule organization. go-plus.json regulation of secretory granule organisation|regulation of secretory granule organization and biogenesis http://purl.obolibrary.org/obo/GO_1904409 GO:0052659 biolink:MolecularActivity inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. MetaCyc:RXN-8730|EC:3.1.3.56|KEGG_REACTION:R03430|Reactome:R-HSA-1855218|RHEA:11392|Reactome:R-HSA-1855213 go-plus.json inositol polyphosphate-5-phosphatase activity|Ins(1,3,4,5)P4 5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|5PTase activity|Ins(1,3,4,5)P(4) 5-phosphatase activity|type I inositol-polyphosphate phosphatase activity|D-myo-inositol (1,3,4,5)-polyphosphate 5-phosphatase activity http://purl.obolibrary.org/obo/GO_0052659 CHEBI:39150 biolink:ChemicalSubstance 4-oxopentanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_39150 chebi_ph7_3 GO:0052658 biolink:MolecularActivity inositol-1,4,5-trisphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate. Reactome:R-HSA-1855222|EC:3.1.3.56|KEGG_REACTION:R03394|RHEA:19797|Reactome:R-HSA-1855174|MetaCyc:3.1.3.56-RXN go-plus.json myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol 1,4,5-trisphosphate phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|inositol triphosphate 5-phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|InsP(3) 5-phosphatase activity|Ins(1,4,5)P3 5-phosphatase activity|5PTase activity|inositol phosphate 5-phosphomonoesterase activity|type I inositol-polyphosphate phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity|inosine triphosphatase activity|InsP3 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity http://purl.obolibrary.org/obo/GO_0052658 GO:1904408 biolink:MolecularActivity melatonin binding Binding to melatonin. go-plus.json http://purl.obolibrary.org/obo/GO_1904408 GO:1904407 biolink:BiologicalProcess positive regulation of nitric oxide metabolic process Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process. go-plus.json up-regulation of nitric oxide metabolism|up regulation of nitric oxide metabolic process|upregulation of nitric oxide metabolism|upregulation of nitric oxide metabolic process|up regulation of nitric oxide metabolism|activation of nitric oxide metabolic process|activation of nitric oxide metabolism|up-regulation of nitric oxide metabolic process|positive regulation of nitric oxide metabolism http://purl.obolibrary.org/obo/GO_1904407 GO:0052657 biolink:MolecularActivity guanine phosphoribosyltransferase activity Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate. KEGG_REACTION:R01229|RHEA:25424|EC:2.4.2.8|MetaCyc:GUANPRIBOSYLTRAN-RXN go-plus.json hypoxanthine-guanine phosphoribosyltransferase activity|6-mercaptopurine phosphoribosyltransferase activity|purine-6-thiol phosphoribosyltransferase activity|guanosine phosphoribosyltransferase activity|Transphosphoribosidase activity|GPRT|guanosine 5'-phosphate pyrophosphorylase activity|guanine-hypoxanthine phosphoribosyltransferase activity|guanylate pyrophosphorylase activity|guanylic pyrophosphorylase activity|GMP pyrophosphorylase activity|6-hydroxypurine phosphoribosyltransferase activity http://purl.obolibrary.org/obo/GO_0052657 CHEBI:88141 biolink:ChemicalSubstance 2''-O-glutaryl-ADP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_88141 GO:1904406 biolink:BiologicalProcess negative regulation of nitric oxide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process. go-plus.json down-regulation of nitric oxide metabolic process|inhibition of nitric oxide metabolism|downregulation of nitric oxide metabolic process|down regulation of nitric oxide metabolic process|inhibition of nitric oxide metabolic process|down regulation of nitric oxide metabolism|downregulation of nitric oxide metabolism|negative regulation of nitric oxide metabolism|down-regulation of nitric oxide metabolism http://purl.obolibrary.org/obo/GO_1904406 GO:1904405 biolink:BiologicalProcess cellular response to formaldehyde Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904405 CHEBI:88143 biolink:ChemicalSubstance (3,4-dimethoxyphenyl)methyloxidanyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_88143 chebi_ph7_3 GO:1904404 biolink:BiologicalProcess response to formaldehyde Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904404 CHEBI:136937 biolink:ChemicalSubstance 4-hydroxy-17beta-estradiol 4-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136937 chebi_ph7_3 CHEBI:88146 biolink:ChemicalSubstance 2''-O-malonyl-ADP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_88146 CHEBI:136936 biolink:ChemicalSubstance 4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136936 chebi_ph7_3 GO:1904403 biolink:BiologicalProcess cellular response to nocodazole Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904403 CHEBI:88145 biolink:ChemicalSubstance 2''-O-succinyl-ADP-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_88145 CHEBI:88148 biolink:ChemicalSubstance 2,3-saturated fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88148 chebi_ph7_3 GO:1904402 biolink:BiologicalProcess response to nocodazole Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904402 GO:1904401 biolink:BiologicalProcess cellular response to Thyroid stimulating hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904401 CHEBI:88147 biolink:ChemicalSubstance 2,5-dihydroxybenzoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88147 chebi_ph7_3 GO:1904400 biolink:BiologicalProcess response to Thyroid stimulating hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904400 CHEBI:88149 biolink:ChemicalSubstance (S)-4-hydroxy-1-pyrroline-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88149 CHEBI:136931 biolink:ChemicalSubstance 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136931 chebi_ph7_3 CHEBI:136933 biolink:ChemicalSubstance 2-hydroxy-17beta-estradiol 2-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136933 chebi_ph7_3 CHEBI:39144 biolink:ChemicalSubstance Lewis base go-plus.json http://purl.obolibrary.org/obo/CHEBI_39144 CHEBI:39143 biolink:ChemicalSubstance Lewis acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39143 CHEBI:39142 biolink:ChemicalSubstance Bronsted base go-plus.json http://purl.obolibrary.org/obo/CHEBI_39142 CHEBI:39141 biolink:ChemicalSubstance Bronsted acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_39141 GO:0052652 biolink:BiologicalProcess cyclic purine nucleotide metabolic process The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine. go-plus.json cyclic purine nucleotide metabolism http://purl.obolibrary.org/obo/GO_0052652 GO:0052651 biolink:BiologicalProcess monoacylglycerol catabolic process The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. go-plus.json monoacylglycerol degradation|monoacylglycerol breakdown|monoacylglycerol catabolism http://purl.obolibrary.org/obo/GO_0052651 GO:0052650 biolink:MolecularActivity NADP-retinol dehydrogenase activity Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+. Reactome:R-HSA-2464822|Reactome:R-HSA-5615668|Reactome:R-HSA-5623643|Reactome:R-HSA-2466861|KEGG_REACTION:R08379|Reactome:R-HSA-2471670|RHEA:25033|Reactome:R-HSA-2464803|Reactome:R-HSA-2465940|Reactome:R-HSA-74872|Reactome:R-HSA-5419165|EC:1.1.1.300|MetaCyc:RXN-10841|Reactome:R-HSA-2465921 go-plus.json NADP(H)-dependent retinol dehydrogenase/reductase activity|retinol dehydrogenase [NADP+] activity|all-trans-retinol dehydrogenase activity|retinol dehydrogenase activity|all-trans retinal reductase activity|retinol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052650 CHEBI:39146 biolink:ChemicalSubstance trichostatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_39146 GO:0052667 biolink:MolecularActivity phosphomethylethanolamine N-methyltransferase activity Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+). RHEA:25321|EC:2.1.1.103|MetaCyc:RXN-5642|KEGG_REACTION:R06868 go-plus.json N-methylethanolamine phosphate N-methyltransferase activity|S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052667 GO:0052666 biolink:MolecularActivity tRNA (cytosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine. Reactome:R-HSA-6788668|Reactome:R-HSA-6788684|Reactome:R-HSA-9024159|MetaCyc:RXN0-5143 go-plus.json tRNA cytosine 2'-methyltransferase activity|tRNA (cytosine 2')-methyltransferase activity|transfer ribonucleate cytosine 2'-methyltransferase activity|tRNA cytosine-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-2'-O-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052666 GO:0052665 biolink:MolecularActivity tRNA (uracil-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil. Reactome:R-HSA-6788707|RHEA:43100|EC:2.1.1.34|MetaCyc:RXN0-5143 go-plus.json S-adenosyl-L-methionine:tRNA uracil-2'-O-methyltransferase activity|transfer ribonucleate uracil 2'-methyltransferase activity|tRNA uracil 2'-methyltransferase activity|tRNA (uracil 2')-methyltransferase activity|S-adenosyl-L-methionine:tRNA (uracil-2'-O-)-methyltransferase activity|tRNA uracil-2'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052665 CHEBI:15193 biolink:ChemicalSubstance tartrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15193 GO:0052664 biolink:MolecularActivity nitroalkane oxidase activity Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2. EC:1.7.3.1|MetaCyc:RXN-11045|KEGG_REACTION:R00799 go-plus.json nitroalkane reductase activity|NAO activity|nitroalkane:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052664 CHEBI:30789 biolink:ChemicalSubstance 4-sulfobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30789 GO:1904419 biolink:BiologicalProcess negative regulation of telomeric loop formation Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation. go-plus.json inhibition of telomeric loop formation|downregulation of t-loop formation|down regulation of t-loop formation|inhibition of t-loop formation|down regulation of t-loop biosynthesis|downregulation of t-loop biosynthesis|down-regulation of telomeric loop formation|down-regulation of t-loop biosynthesis|negative regulation of t-loop biosynthesis|down-regulation of t-loop formation|negative regulation of t-loop formation|inhibition of t-loop biosynthesis|downregulation of telomeric loop formation|down regulation of telomeric loop formation http://purl.obolibrary.org/obo/GO_1904419 GO:0052669 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052669 GO:0052668 biolink:MolecularActivity CTP:farnesol kinase activity Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+. EC:2.7.1.216|RHEA:51680|MetaCyc:RXN-11625 go-plus.json farnesol kinase activity|farnesol phosphotransferase activity|CTP:2-trans,-6-trans-farnesol kinase activity|trans,trans-farnesol kinase activity|CTP:2-trans,-6-trans-farnesol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052668 GO:1904418 biolink:BiologicalProcess regulation of telomeric loop formation Any process that modulates the frequency, rate or extent of telomeric loop formation. go-plus.json regulation of t-loop formation|regulation of t-loop biosynthesis http://purl.obolibrary.org/obo/GO_1904418 GO:1904417 biolink:BiologicalProcess positive regulation of xenophagy Any process that activates or increases the frequency, rate or extent of xenophagy. go-plus.json upregulation of xenophagy|up regulation of xenophagy|activation of xenophagy|up-regulation of xenophagy http://purl.obolibrary.org/obo/GO_1904417 CHEBI:136906 biolink:ChemicalSubstance hyocholate 6-O-(beta-D-glucuronide)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136906 chebi_ph7_3 CHEBI:136905 biolink:ChemicalSubstance hyodeoxycholate 6-O-(beta-D-glucuronide)(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136905 chebi_ph7_3 GO:1904416 biolink:BiologicalProcess negative regulation of xenophagy Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy. go-plus.json down regulation of xenophagy|downregulation of xenophagy|down-regulation of xenophagy|inhibition of xenophagy http://purl.obolibrary.org/obo/GO_1904416 GO:1904415 biolink:BiologicalProcess regulation of xenophagy Any process that modulates the frequency, rate or extent of xenophagy. go-plus.json http://purl.obolibrary.org/obo/GO_1904415 CHEBI:136904 biolink:ChemicalSubstance hyocholic acid 24-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136904 chebi_ph7_3 GO:1904414 biolink:BiologicalProcess positive regulation of cardiac ventricle development Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. go-plus.json up-regulation of cardiac ventricle development|upregulation of cardiac ventricle development|up regulation of cardiac ventricle development|activation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_1904414 CHEBI:136903 biolink:ChemicalSubstance hyodeoxycholic acid 24-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136903 chebi_ph7_3 GO:1904413 biolink:BiologicalProcess negative regulation of cardiac ventricle development Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. go-plus.json inhibition of cardiac ventricle development|down regulation of cardiac ventricle development|downregulation of cardiac ventricle development|down-regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_1904413 CHEBI:29792 biolink:ChemicalSubstance hydroperoxy group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29792 chebi_ph7_3 GO:1904412 biolink:BiologicalProcess regulation of cardiac ventricle development Any process that modulates the frequency, rate or extent of cardiac ventricle development. go-plus.json http://purl.obolibrary.org/obo/GO_1904412 UBERON:2005117 biolink:AnatomicalEntity anterior lateral line primordium A migrating group of cells originating from an anterior lateral line placode. The primordium deposits neuromasts and interneuromasts between them during its migration. go-plus.json anterior lateral line primordia http://purl.obolibrary.org/obo/UBERON_2005117 GO:1904411 biolink:BiologicalProcess positive regulation of secretory granule organization Any process that activates or increases the frequency, rate or extent of secretory granule organization. go-plus.json upregulation of secretory granule organization and biogenesis|up-regulation of secretory granule organization|activation of secretory granule organization|positive regulation of secretory granule organisation|up regulation of secretory granule organisation|up regulation of secretory granule organization and biogenesis|positive regulation of secretory granule organization and biogenesis|up regulation of secretory granule organization|activation of secretory granule organization and biogenesis|upregulation of secretory granule organisation|up-regulation of secretory granule organization and biogenesis|upregulation of secretory granule organization|up-regulation of secretory granule organisation|activation of secretory granule organisation http://purl.obolibrary.org/obo/GO_1904411 CHEBI:136908 biolink:ChemicalSubstance (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl pantetheine-4-phosphorylserine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136908 chebi_ph7_3 GO:1904410 biolink:BiologicalProcess negative regulation of secretory granule organization Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization. go-plus.json down regulation of secretory granule organization and biogenesis|down-regulation of secretory granule organisation|negative regulation of secretory granule organisation|downregulation of secretory granule organization and biogenesis|down-regulation of secretory granule organization|downregulation of secretory granule organisation|down-regulation of secretory granule organization and biogenesis|negative regulation of secretory granule organization and biogenesis|down regulation of secretory granule organisation|inhibition of secretory granule organisation|downregulation of secretory granule organization|down regulation of secretory granule organization|inhibition of secretory granule organization|inhibition of secretory granule organization and biogenesis http://purl.obolibrary.org/obo/GO_1904410 CHEBI:29793 biolink:ChemicalSubstance hydridodioxygen(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29793 CHEBI:136907 biolink:ChemicalSubstance (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl pantetheine-4-phosphorylserine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136907 chebi_ph7_3 GO:1904420 biolink:BiologicalProcess positive regulation of telomeric loop formation Any process that activates or increases the frequency, rate or extent of telomeric loop formation. go-plus.json up regulation of telomeric loop formation|up-regulation of t-loop biosynthesis|positive regulation of t-loop formation|up regulation of t-loop formation|upregulation of telomeric loop formation|upregulation of t-loop biosynthesis|upregulation of t-loop formation|up-regulation of telomeric loop formation|activation of telomeric loop formation|up regulation of t-loop biosynthesis|activation of t-loop biosynthesis|positive regulation of t-loop biosynthesis|up-regulation of t-loop formation|activation of t-loop formation http://purl.obolibrary.org/obo/GO_1904420 CHEBI:39116 biolink:ChemicalSubstance pyrethroid ester insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39116 CHEBI:136902 biolink:ChemicalSubstance lithocholic acid 24-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136902 chebi_ph7_3 CHEBI:136901 biolink:ChemicalSubstance deoxycholic acid 24-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136901 chebi_ph7_3 CHEBI:136900 biolink:ChemicalSubstance cholic acid 24-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136900 chebi_ph7_3 CHEBI:30782 biolink:ChemicalSubstance acetylenedicarboxylate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30782 GO:0052663 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0052663 CHEBI:30781 biolink:ChemicalSubstance butynedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30781 GO:0052662 biolink:MolecularActivity zeaxanthin epoxidase activity Catalysis of the reaction: all-trans-zeaxanthin + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]. KEGG_REACTION:R07200|RHEA:24084|KEGG_REACTION:R06946|KEGG_REACTION:R07199|KEGG_REACTION:R06947|MetaCyc:RXN-7979|MetaCyc:RXN-7978|EC:1.14.15.21 go-plus.json antheraxanthin epoxidase activity|zea-epoxidase activity|zeaxanthin epoxidase [overall] activity http://purl.obolibrary.org/obo/GO_0052662 CHEBI:30780 biolink:ChemicalSubstance maleate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30780 chebi_ph7_3 GO:0052661 biolink:MolecularActivity S-lactaldehyde reductase activity Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+. MetaCyc:LACTALDREDUCT-RXN|RHEA:15933|KEGG_REACTION:R02258 go-plus.json L-lactaldehyde:propanediol oxidoreductase activity|(S)-propane-1,2-diol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052661 GO:0052660 biolink:MolecularActivity R-lactaldehyde reductase activity Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+. KEGG_REACTION:R03080|MetaCyc:RXN-8641|RHEA:23872 go-plus.json D-lactaldehyde:propanediol oxidoreductase activity|(R)-propane-1,2-diol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052660 GO:0052678 biolink:MolecularActivity levopimaradiene synthase activity Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate. RHEA:25548|EC:4.2.3.32|KEGG_REACTION:R06302|MetaCyc:4.2.3.32-RXN go-plus.json ent-copalyl-diphosphate diphosphate-lyase [ent-abieta-8(14),12-diene-forming] activity http://purl.obolibrary.org/obo/GO_0052678 GO:0052677 biolink:MolecularActivity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+. MetaCyc:RXN-7971|RHEA:21276|KEGG_REACTION:R07143 go-plus.json D-arabinitol dehydrogenase 1 activity|D-arabinitol:NADP+ dehydrogenase activity|ARD1p|NADP+-dependent D-arabinitol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052677 GO:0052676 biolink:MolecularActivity 3-methylbutanol:NAD oxidoreductase activity Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde. RHEA:18529|KEGG_REACTION:R05685 go-plus.json 3-methylbutyraldehyde reductase (NAD) activity|3-methylbutanal reductase (NAD) activity|isoamyl alcohol oxidase (NAD) activity|3-methylbutanol:NAD+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052676 GO:0052675 biolink:MolecularActivity 3-methylbutanol:NADP oxidoreductase activity Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde. RHEA:18525|KEGG_REACTION:R05686 go-plus.json 3-methylbutanol:NADP+ oxidoreductase activity|isoamyl alcohol oxidase (NADP) activity|3-methylbutanal reductase (NADP) activity|3-methylbutyraldehyde reductase (NADP) activity http://purl.obolibrary.org/obo/GO_0052675 CHEBI:88164 biolink:ChemicalSubstance 3-chloroalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88164 GO:1904429 biolink:BiologicalProcess regulation of t-circle formation Any process that modulates the frequency, rate or extent of t-circle formation. go-plus.json regulation of telomeric circle formation http://purl.obolibrary.org/obo/GO_1904429 GO:0052679 biolink:MolecularActivity terpentetriene synthase activity Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene. MetaCyc:RXN-9455|RHEA:25617|EC:4.2.3.36 go-plus.json terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming) activity http://purl.obolibrary.org/obo/GO_0052679 CHEBI:30797 biolink:ChemicalSubstance (S)-malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30797 GO:1904428 biolink:BiologicalProcess negative regulation of tubulin deacetylation Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation. go-plus.json down-regulation of tubulin deacetylation|inhibition of tubulin deacetylation|down regulation of tubulin deacetylation|downregulation of tubulin deacetylation http://purl.obolibrary.org/obo/GO_1904428 CHEBI:88166 biolink:ChemicalSubstance (S)-2-methylbutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88166 chebi_ph7_3 GO:1904427 biolink:BiologicalProcess positive regulation of calcium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport. go-plus.json up-regulation of calcium ion membrane transport|activation of calcium ion membrane transport|up-regulation of transmembrane calcium transport|upregulation of calcium ion transmembrane transport|positive regulation of calcium ion membrane transport|upregulation of transmembrane calcium transport|up regulation of calcium ion transmembrane transport|up regulation of calcium ion membrane transport|activation of calcium ion transmembrane transport|up regulation of transmembrane calcium transport|activation of transmembrane calcium transport|positive regulation of transmembrane calcium transport|upregulation of calcium ion membrane transport|up-regulation of calcium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904427 CHEBI:136916 biolink:ChemicalSubstance 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronide](2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136916 chebi_ph7_3 GO:1904426 biolink:BiologicalProcess positive regulation of GTP binding Any process that activates or increases the frequency, rate or extent of GTP binding. go-plus.json up regulation of GTP binding|activation of GTP binding|up-regulation of GTP binding|upregulation of GTP binding http://purl.obolibrary.org/obo/GO_1904426 GO:1904425 biolink:BiologicalProcess negative regulation of GTP binding Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding. go-plus.json down-regulation of GTP binding|inhibition of GTP binding|down regulation of GTP binding|downregulation of GTP binding http://purl.obolibrary.org/obo/GO_1904425 CHEBI:88167 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_88167 chebi_ph7_3 CHEBI:136914 biolink:ChemicalSubstance 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronide)(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136914 chebi_ph7_3 GO:1904424 biolink:BiologicalProcess regulation of GTP binding Any process that modulates the frequency, rate or extent of GTP binding. go-plus.json http://purl.obolibrary.org/obo/GO_1904424 GO:1904423 biolink:CellularComponent dehydrodolichyl diphosphate synthase complex A protein complex which is capable of dehydrodolichyl diphosphate synthase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1904423 GO:1904422 biolink:BiologicalProcess cellular response to D-galactosamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904422 GO:1904421 biolink:BiologicalProcess response to D-galactosamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904421 GO:1904431 biolink:BiologicalProcess positive regulation of t-circle formation Any process that activates or increases the frequency, rate or extent of t-circle formation. go-plus.json positive regulation of telomeric circle formation|up regulation of telomeric circle formation|up regulation of t-circle formation|upregulation of telomeric circle formation|upregulation of t-circle formation|up-regulation of telomeric circle formation|activation of telomeric circle formation|up-regulation of t-circle formation|activation of t-circle formation http://purl.obolibrary.org/obo/GO_1904431 GO:1904430 biolink:BiologicalProcess negative regulation of t-circle formation Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation. go-plus.json down-regulation of t-circle formation|downregulation of telomeric circle formation|down regulation of telomeric circle formation|inhibition of telomeric circle formation|downregulation of t-circle formation|down regulation of t-circle formation|inhibition of t-circle formation|down-regulation of telomeric circle formation|negative regulation of telomeric circle formation http://purl.obolibrary.org/obo/GO_1904430 CHEBI:39128 biolink:ChemicalSubstance magnesium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_39128 CHEBI:39127 biolink:ChemicalSubstance magnesium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_39127 CHEBI:136913 biolink:ChemicalSubstance monoacyl-sn-glycero-3-phospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136913 chebi_ph7_3 CHEBI:136912 biolink:ChemicalSubstance 1,2-diacyl-sn-glycero-3-phospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136912 chebi_ph7_3 CHEBI:136911 biolink:ChemicalSubstance N-(4-ammoniobutylidene)-L-lysinium(2+) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136911 chebi_ph7_3 CHEBI:136910 biolink:ChemicalSubstance O-[S-(7-oxoheptanoyl)pantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_136910 chebi_ph7_3 GO:0052670 biolink:MolecularActivity geraniol kinase activity Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate. go-plus.json geraniol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052670 CHEBI:30796 biolink:ChemicalSubstance (R)-malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30796 CHEBI:15176 biolink:ChemicalSubstance tRNA(Glx) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15176 CHEBI:30795 biolink:ChemicalSubstance malonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30795 CHEBI:30794 biolink:ChemicalSubstance malonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30794 CHEBI:30793 biolink:ChemicalSubstance 2-chlorobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30793 GO:0052674 biolink:MolecularActivity ent-pimara-9(11),15-diene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate. MetaCyc:RXN-9299|EC:4.2.3.31|RHEA:25544 go-plus.json ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming] activity|PMD synthase activity http://purl.obolibrary.org/obo/GO_0052674 GO:0052673 biolink:MolecularActivity prenol kinase activity Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity. go-plus.json prenyl alcohol kinase activity|prenyl alcohol phosphotransferase activity|prenol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052673 CHEBI:15172 biolink:ChemicalSubstance tRNA(Asx) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15172 GO:0052672 biolink:MolecularActivity CTP:geranylgeraniol kinase activity Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP. EC:2.7.1.216|MetaCyc:RXN-11629 go-plus.json CTP:geranylgeraniol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052672 CHEBI:39124 biolink:ChemicalSubstance calcium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_39124 CHEBI:39123 biolink:ChemicalSubstance calcium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_39123 GO:0052671 biolink:MolecularActivity geranylgeraniol kinase activity Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate. go-plus.json geranylgeraniol phosphotransferase activity http://purl.obolibrary.org/obo/GO_0052671 CHEBI:78703 biolink:ChemicalSubstance 2-arachidonoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78703 CHEBI:78709 biolink:ChemicalSubstance 3-deoxy-D-threo-hex-2-ulosaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78709 CHEBI:78700 biolink:ChemicalSubstance 9-oxononanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78700 CHEBI:78715 biolink:ChemicalSubstance 1,4,5,6-tetrahydropyrimidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_78715 CHEBI:78718 biolink:ChemicalSubstance UDP-alpha-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78718 chebi_ph7_3 CHEBI:78717 biolink:ChemicalSubstance UDP-alpha-D-galactosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78717 chebi_ph7_3 CHEBI:78712 biolink:ChemicalSubstance tetrahydropyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78712 CHEBI:78723 biolink:ChemicalSubstance 3'-(D-tyrosyl)adenylyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_78723 chebi_ph7_3 CHEBI:78737 biolink:ChemicalSubstance fructose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78737 CHEBI:78736 biolink:ChemicalSubstance D-fructose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78736 CHEBI:78730 biolink:ChemicalSubstance 9(R)-HODE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78730 CHEBI:78734 biolink:ChemicalSubstance tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78734 CHEBI:78732 biolink:ChemicalSubstance 9-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78732 CHEBI:78731 biolink:ChemicalSubstance 9(R)-HPETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_78731 PR:000016964 biolink:Protein ubiquitin D A protein that is a translation product of the human UBD gene or a 1:1 ortholog thereof. go-plus.json UBD|FAT10|ubiquitin-like protein FAT10|diubiquitin http://purl.obolibrary.org/obo/PR_000016964 PR:000016963 biolink:Protein polyubiquitin-C A polyubiquitin that is a translation product of the human UBC gene or a 1:1 ortholog thereof. go-plus.json UBC http://purl.obolibrary.org/obo/PR_000016963 CHEBI:64106 biolink:ChemicalSubstance protein kinase agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_64106 CHEBI:78741 biolink:ChemicalSubstance oxidopamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78741 NCBITaxon:13333 biolink:OrganismalEntity Amborella trichopoda go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_13333 PR:000016954 biolink:Protein ubiquitin-60S ribosomal protein L40 A protein that is a translation product of the human UBA52 gene or a 1:1 ortholog thereof. go-plus.json UBA52|UBCEP2|CEP52|60S ribosomal protein L40 http://purl.obolibrary.org/obo/PR_000016954 NCBITaxon:13332 biolink:OrganismalEntity Amborella go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_13332 GO:0003699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003699 CHEBI:78768 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78768 chebi_ph7_3 GO:0003696 biolink:MolecularActivity satellite DNA binding Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0003696 GO:0003695 biolink:MolecularActivity obsolete random coil DNA binding OBSOLETE. Binding to DNA in a random coil configuration. go-plus.json random coil binding http://purl.obolibrary.org/obo/GO_0003695 GO:0003698 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003698 GO:0003697 biolink:MolecularActivity single-stranded DNA binding Binding to single-stranded DNA. go-plus.json ssDNA binding http://purl.obolibrary.org/obo/GO_0003697 GO:0003692 biolink:MolecularActivity left-handed Z-DNA binding Binding to DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags. go-plus.json http://purl.obolibrary.org/obo/GO_0003692 CHEBI:64121 biolink:ChemicalSubstance P-factor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64121 GO:0003691 biolink:MolecularActivity double-stranded telomeric DNA binding Binding to double-stranded telomere-associated DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0003691 GO:0003694 biolink:MolecularActivity obsolete plasmid binding OBSOLETE. Interacting selectively with a plasmid, an extrachromosomal genetic element usually characterized as a covalently continuous double stranded DNA molecule found in bacteria and some other microorganisms. go-plus.json plasmid binding|plasmid-associated protein http://purl.obolibrary.org/obo/GO_0003694 CHEBI:64120 biolink:ChemicalSubstance M-factor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64120 GO:0003693 biolink:MolecularActivity P-element binding Binding to a P-element, a class of Drosophila transposon responsible for hybrid dysgenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0003693 GO:0003690 biolink:MolecularActivity double-stranded DNA binding Binding to double-stranded DNA. go-plus.json dsDNA binding http://purl.obolibrary.org/obo/GO_0003690 CHEBI:64124 biolink:ChemicalSubstance phytosphingosine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64124 chebi_ph7_3 CHEBI:40196 biolink:ChemicalSubstance N(6)-methyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_40196 CHEBI:136986 biolink:ChemicalSubstance 2-hydroxyhexacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_136986 CHEBI:136985 biolink:ChemicalSubstance S-prenyl-L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_136985 chebi_ph7_3 CHEBI:136984 biolink:ChemicalSubstance EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_136984 CHEBI:136983 biolink:ChemicalSubstance (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136983 chebi_ph7_3 CHEBI:136989 biolink:ChemicalSubstance N-[(5Z,11Z,14Z)-8,9-epoxyicosatrienoyl]ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136989 chebi_ph7_3 CHEBI:136988 biolink:ChemicalSubstance N-[(8Z,11Z,14Z)-5,6-epoxyicosatrienoyl]ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136988 chebi_ph7_3 CHEBI:136987 biolink:ChemicalSubstance N-[(2S)-2-amino-2-carboxyethyl]-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136987 CHEBI:78762 biolink:ChemicalSubstance 1-oleoyl-sn-glycero-3-phospho-D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78762 chebi_ph7_3 CHEBI:136982 biolink:ChemicalSubstance 5alpha-dihydrotestosterone sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_136982 chebi_ph7_3 CHEBI:78765 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78765 chebi_ph7_3 CHEBI:136980 biolink:ChemicalSubstance 2-hydroxy-3-O-methyl estrone go-plus.json http://purl.obolibrary.org/obo/CHEBI_136980 chebi_ph7_3 CHEBI:78779 biolink:ChemicalSubstance O-[S-(13Z)-3-oxooctadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78779 chebi_ph7_3 CHEBI:146306 biolink:ChemicalSubstance partially-defined glycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_146306 CHEBI:64133 biolink:ChemicalSubstance EC 2.5.1.58 (protein farnesyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64133 CHEBI:64130 biolink:ChemicalSubstance pyrazinoindole go-plus.json http://purl.obolibrary.org/obo/CHEBI_64130 CHEBI:64136 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-decaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64136 CHEBI:136997 biolink:ChemicalSubstance L-polyhomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136997 CHEBI:136996 biolink:ChemicalSubstance 9-[(9Z)-octadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_136996 CHEBI:136994 biolink:ChemicalSubstance 2-(glutathion-S-yl)-1,4-hydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_136994 CHEBI:136999 biolink:ChemicalSubstance L-trihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136999 CHEBI:136998 biolink:ChemicalSubstance L-dihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136998 CHEBI:78772 biolink:ChemicalSubstance alpha-ascarylopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_78772 chebi_ph7_3 CHEBI:78771 biolink:ChemicalSubstance ascarylopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_78771 chebi_ph7_3 CHEBI:78778 biolink:ChemicalSubstance O-[S-(11Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78778 chebi_ph7_3 CHEBI:136992 biolink:ChemicalSubstance N-(20-hydroxyarachidonoyl)ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136992 chebi_ph7_3 CHEBI:78776 biolink:ChemicalSubstance O-(S-3-oxoacylpantetheine-4'-phosphoryl)-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78776 chebi_ph7_3 CHEBI:136991 biolink:ChemicalSubstance N-[(5Z,8Z,11Z)-14,15-epoxyicosatrienoyl]ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136991 chebi_ph7_3 CHEBI:136990 biolink:ChemicalSubstance N-[(5Z,8Z,14Z)-11,12-epoxyicosatrienoyl]ethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_136990 chebi_ph7_3 GO:1904399 biolink:MolecularActivity heparan sulfate binding Binding to heparan sulfate. go-plus.json http://purl.obolibrary.org/obo/GO_1904399 CHEBI:29704 biolink:ChemicalSubstance valiolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_29704 chebi_ph7_3 CHEBI:29706 biolink:ChemicalSubstance 10-deoxymethymycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29706 CHEBI:29701 biolink:ChemicalSubstance tyrocidine A go-plus.json http://purl.obolibrary.org/obo/CHEBI_29701 CHEBI:29700 biolink:ChemicalSubstance tylactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_29700 chebi_ph7_3 CHEBI:29703 biolink:ChemicalSubstance validamycin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_29703 OBO:uberon/core#channels_from biolink:OntologyClass channels_from channels_from go-plus.json http://purl.obolibrary.org/obo/uberon/core#channels_from CHEBI:8504 biolink:ChemicalSubstance prostanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_8504 NCBITaxon:37104 biolink:OrganismalEntity Trichomonadida go-plus.json trichomonads|trichomonads http://purl.obolibrary.org/obo/NCBITaxon_37104 GO:0003832 biolink:MolecularActivity beta-alanyl-dopamine hydrolase activity Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine. go-plus.json N-beta-alanyl-dopamine hydrolase activity|NBAD hydrolase activity http://purl.obolibrary.org/obo/GO_0003832 CHEBI:88070 biolink:ChemicalSubstance monooctanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_88070 chebi_ph7_3 GO:0003831 biolink:MolecularActivity beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide. Reactome:R-HSA-1912352|MetaCyc:2.4.1.38-RXN|Reactome:R-HSA-3656230|Reactome:R-HSA-2025723|EC:2.4.1.38|Reactome:R-HSA-975919|Reactome:R-HSA-2046265|Reactome:R-HSA-9035949|RHEA:22932|Reactome:R-HSA-9035950|Reactome:R-HSA-2046298|Reactome:R-HSA-4793956 go-plus.json UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|uridine diphosphogalactose-glycoprotein galactosyltransferase activity|UDPgalactose-glycoprotein galactosyltransferase activity|GalT activity|thyroid galactosyltransferase activity|UDP-galactose--glycoprotein galactosyltransferase activity|glycoprotein 4-beta-galactosyltransferase activity|beta-N-acetyl-beta-(1,4)-galactosyltransferase activity|beta-N-acetyl-beta-1,4-galactosyltransferase activity|glycoprotein beta-galactosyltransferase activity|UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|thyroid glycoprotein beta-galactosyltransferase|glycoprotein 4-beta-galactosyl-transferase activity http://purl.obolibrary.org/obo/GO_0003831 GO:0003834 biolink:MolecularActivity beta-carotene 15,15'-dioxygenase activity Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal. KEGG_REACTION:R00032|MetaCyc:BETA-CAROTENE-1515-DIOXYGENASE-RXN|Reactome:R-HSA-975635|EC:1.13.11.63|RHEA:32887 go-plus.json carotene 15,15'-dioxygenase activity|carotene dioxygenase activity|beta-carotene 15,15'-monooxygenase activity http://purl.obolibrary.org/obo/GO_0003834 CHEBI:88072 biolink:ChemicalSubstance (3S,5Z)-3-hydroxytetradec-5-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88072 CHEBI:30769 biolink:ChemicalSubstance citric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30769 GO:0003833 biolink:MolecularActivity beta-alanyl-dopamine synthase activity Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine). go-plus.json NBAD transferase activity|N-beta-alanyl dopamine synthetase activity http://purl.obolibrary.org/obo/GO_0003833 CHEBI:30768 biolink:ChemicalSubstance propionic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30768 CHEBI:88071 biolink:ChemicalSubstance monosialodiglycosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88071 CHEBI:30767 biolink:ChemicalSubstance (R)-tropic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30767 CHEBI:88073 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88073 chebi_ph7_3 CHEBI:30766 biolink:ChemicalSubstance (S)-tropic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30766 GO:0003830 biolink:MolecularActivity beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R. MetaCyc:2.4.1.144-RXN|EC:2.4.1.144|Reactome:R-HSA-975926|RHEA:15509 go-plus.json beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase III activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity|GnTIII activity|UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0003830 CHEBI:88076 biolink:ChemicalSubstance monosialotriglycosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88076 CHEBI:30765 biolink:ChemicalSubstance tropic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30765 GO:1904319 biolink:BiologicalProcess negative regulation of smooth muscle contraction involved in micturition Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition. go-plus.json downregulation of smooth muscle contraction involved in urination|down-regulation of smooth muscle contraction involved in micturition|down-regulation of smooth muscle contraction involved in urination|negative regulation of smooth muscle contraction involved in urination|inhibition of smooth muscle contraction involved in micturition|inhibition of urinary bladder smooth muscle contraction involved in micturition|down regulation of urinary bladder smooth muscle contraction involved in micturition|inhibition of smooth muscle contraction involved in urination|downregulation of urinary bladder smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in micturition|downregulation of smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in urination|down-regulation of urinary bladder smooth muscle contraction involved in micturition|negative regulation of urinary bladder smooth muscle contraction involved in micturition http://purl.obolibrary.org/obo/GO_1904319 CHEBI:30764 biolink:ChemicalSubstance 3-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30764 CHEBI:88075 biolink:ChemicalSubstance trisialodiglycosylceramide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88075 GO:1904318 biolink:BiologicalProcess regulation of smooth muscle contraction involved in micturition Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition. go-plus.json regulation of urinary bladder smooth muscle contraction involved in micturition|regulation of smooth muscle contraction involved in urination http://purl.obolibrary.org/obo/GO_1904318 CHEBI:88078 biolink:ChemicalSubstance trisialotriglycosylceramide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88078 CHEBI:88077 biolink:ChemicalSubstance disialotriglycosylceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88077 GO:1904317 biolink:BiologicalProcess cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus. go-plus.json cellular response to PAF|cellular response to platelet-activating factor http://purl.obolibrary.org/obo/GO_1904317 CHEBI:29773 biolink:ChemicalSubstance aminooxidanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29773 GO:1904316 biolink:BiologicalProcess response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus. go-plus.json response to platelet-activating factor|response to PAF http://purl.obolibrary.org/obo/GO_1904316 GO:0062130 biolink:CellularComponent adhesive extracellular matrix A extracellular matrix which attaches an organism to a substrate. go-plus.json puparial glue http://purl.obolibrary.org/obo/GO_0062130 CHEBI:88079 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88079 chebi_ph7_3 GO:1904315 biolink:MolecularActivity transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. go-plus.json ionotropic neurotransmitter receptor activity involved in regulation of post-synaptic membrane potential|ionotropic neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_1904315 goslim_synapse CHEBI:29775 biolink:ChemicalSubstance selenol group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29775 chebi_ph7_3 GO:1904314 biolink:BiologicalProcess cellular response to methamphetamine hydrochloride Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus. go-plus.json cellular response to methamphetamine HCL http://purl.obolibrary.org/obo/GO_1904314 GO:0062132 biolink:BiologicalProcess regulation of L-glutamine biosynthetic process Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0062132 GO:1904313 biolink:BiologicalProcess response to methamphetamine hydrochloride Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus. go-plus.json response to methamphetamine HCL http://purl.obolibrary.org/obo/GO_1904313 NCBITaxon:3208 biolink:OrganismalEntity Bryophyta go-plus.json Bryopsida|mosses|Musci|mosses|bryophytes http://purl.obolibrary.org/obo/NCBITaxon_3208 GO:0062131 biolink:MolecularActivity 3-butenylglucosinolate 2-hydroxylase activity Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O. MetaCyc:RXNQT-4343|RHEA:60628 go-plus.json But-3-enyl Glucosinolate-2-hydroxylase activity http://purl.obolibrary.org/obo/GO_0062131 GO:0062134 biolink:BiologicalProcess positive regulation of L-glutamine biosynthetic process Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0062134 GO:1904312 biolink:BiologicalProcess cellular response to gold(3+) Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904312 CHEBI:29772 biolink:ChemicalSubstance hydroxyazanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_29772 GO:0062133 biolink:BiologicalProcess negative regulation of L-glutamine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0062133 GO:1904311 biolink:BiologicalProcess response to gold(3+) Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904311 GO:1904321 biolink:BiologicalProcess response to forskolin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904321 GO:0062136 biolink:CellularComponent low-density lipoprotein receptor complex A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors. go-plus.json low-density lipoprotein particle receptor complex|LDL receptor complex|LDLR complex http://purl.obolibrary.org/obo/GO_0062136 GO:1904320 biolink:BiologicalProcess positive regulation of smooth muscle contraction involved in micturition Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition. go-plus.json up regulation of urinary bladder smooth muscle contraction involved in micturition|upregulation of smooth muscle contraction involved in urination|positive regulation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in micturition|activation of smooth muscle contraction involved in micturition|activation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in urination|positive regulation of smooth muscle contraction involved in urination|up-regulation of urinary bladder smooth muscle contraction involved in micturition|activation of smooth muscle contraction involved in urination|up-regulation of smooth muscle contraction involved in micturition|upregulation of urinary bladder smooth muscle contraction involved in micturition|up-regulation of smooth muscle contraction involved in urination|upregulation of smooth muscle contraction involved in micturition http://purl.obolibrary.org/obo/GO_1904320 NCBITaxon:171549 biolink:OrganismalEntity Bacteroidales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_171549 GO:0062137 biolink:CellularComponent cargo receptor complex Any protein complex that is part of a membrane and which functions as a cargo receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0062137 NCBITaxon:2684882 biolink:OrganismalEntity Zygnematophycidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2684882 GO:0062139 biolink:BiologicalProcess camera-type eye photoreceptor cell development The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0062139 CHEBI:30763 biolink:ChemicalSubstance 4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30763 GO:0003839 biolink:MolecularActivity gamma-glutamylcyclotransferase activity Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid. EC:4.3.2.9|Reactome:R-HSA-6785928|RHEA:20505|Reactome:R-HSA-1247922|MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN go-plus.json gamma-L-glutamylcyclotransferase activity|(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)|gamma-glutamyl-amino acid cyclotransferase activity|L-glutamic cyclase activity http://purl.obolibrary.org/obo/GO_0003839 CHEBI:30762 biolink:ChemicalSubstance salicylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_30762 chebi_ph7_3 NCBITaxon:2743709 biolink:OrganismalEntity Danionidae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2743709 GO:0003836 biolink:MolecularActivity beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R. MetaCyc:2.4.99.4-RXN|Reactome:R-HSA-1022129|Reactome:R-HSA-3656258|Reactome:R-HSA-981497|Reactome:R-HSA-2046285|EC:2.4.99.4|Reactome:R-HSA-9605600|RHEA:21616|Reactome:R-HSA-4084984|Reactome:R-HSA-1912378|Reactome:R-HSA-9603987 go-plus.json CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity http://purl.obolibrary.org/obo/GO_0003836 GO:0003835 biolink:MolecularActivity beta-galactoside alpha-2,6-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine. MetaCyc:2.4.99.1-RXN|Reactome:R-HSA-4085033|Reactome:R-HSA-977071|Reactome:R-HSA-977228|Reactome:R-HSA-975902|EC:2.4.99.1|RHEA:11836 go-plus.json beta-galactosamide alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity http://purl.obolibrary.org/obo/GO_0003835 GO:0003838 biolink:MolecularActivity sterol 24-C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol. MetaCyc:RXN-11201|MetaCyc:RXN3O-178|RHEA:21128|EC:2.1.1.41 go-plus.json S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity|phytosterol methyltransferase activity|delta24-sterol methyltransferase activity|delta(24)-sterol methyltransferase activity|S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity|S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity|SMT1 activity|S-adenosyl-4-methionine:sterol delta24-methyltransferase activity|S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity|delta(24)-methyltransferase activity|sterol 24C methyltransferase activity|zymosterol-24-methyltransferase activity|24-sterol C-methyltransferase activity|delta24-methyltransferase activity|delta(24)-sterol C-methyltransferase activity http://purl.obolibrary.org/obo/GO_0003838 GO:0003837 biolink:MolecularActivity beta-ureidopropionase activity Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3. EC:3.5.1.6|Reactome:R-HSA-73620|RHEA:11184|MetaCyc:BETA-UREIDOPROPIONASE-RXN|Reactome:R-HSA-73591 go-plus.json N-carbamoyl-beta-alanine amidohydrolase activity http://purl.obolibrary.org/obo/GO_0003837 GO:0003843 biolink:MolecularActivity 1,3-beta-D-glucan synthase activity Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1). EC:2.4.1.34|RHEA:21476|MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN go-plus.json beta-1,3-glucan synthetase activity|1,3-beta-D-glucan synthetase activity|UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|UDP-glucose-1,3-beta-glucan glucosyltransferase activity|UDP-glucose:(1,3)beta-glucan synthase activity|(1,3)-beta-glucan (callose) synthase activity|beta-1,3-glucan synthase activity|1,3-beta-D-glucan-UDP glucosyltransferase activity|UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity|1,3-beta-glucan-uridine diphosphoglucosyltransferase activity|callose synthetase activity|paramylon synthetase|uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity|GS-II|UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|UDPglucose-1,3-beta-D-glucan glucosyltransferase activity|1,3-beta-glucan synthase activity|UDP-glucose-beta-glucan glucosyltransferase activity|callose synthase activity http://purl.obolibrary.org/obo/GO_0003843 NCBITaxon:3216 biolink:OrganismalEntity Funariaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3216 GO:0003842 biolink:MolecularActivity 1-pyrroline-5-carboxylate dehydrogenase activity Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+). Reactome:R-HSA-6784399|Reactome:R-HSA-70679|EC:1.2.1.88|RHEA:16417|MetaCyc:PYRROLINECARBDEHYDROG-RXN go-plus.json delta1-pyrroline-5-carboxylate dehydrogenase activity|1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity|pyrroline-5-carboxylic acid dehydrogenase activity|1-pyrroline dehydrogenase|L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity|pyrroline-5-carboxylate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0003842 NCBITaxon:3215 biolink:OrganismalEntity Funariales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3215 GO:0003845 biolink:MolecularActivity 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+). Wikipedia:11beta-hydroxysteroid_dehydrogenase|Reactome:R-HSA-194023|MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN go-plus.json corticosteroid 11-reductase|11beta-hydroxysteroid dehydrogenase|beta-hydroxysteroid dehydrogenase|11beta-hydroxy steroid dehydrogenase|corticosteroid 11beta-dehydrogenase http://purl.obolibrary.org/obo/GO_0003845 gocheck_do_not_annotate CHEBI:88061 biolink:ChemicalSubstance polyamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88061 NCBITaxon:3218 biolink:OrganismalEntity Physcomitrium patens go-plus.json Physcomitrella patens subsp. patens|Phascum patens|Physcomitrella patens http://purl.obolibrary.org/obo/NCBITaxon_3218 GO:0003844 biolink:MolecularActivity 1,4-alpha-glucan branching enzyme activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain. EC:2.4.1.18|Reactome:R-HSA-3878762|MetaCyc:GLYCOGEN-BRANCH-RXN|Reactome:R-HSA-3322005|Reactome:R-HSA-3322016|Reactome:R-HSA-3322057 go-plus.json glycogen branching enzyme activity|enzymatic branching factor|Q-enzyme|alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity|1,4-glucan-6-(1,4-glucano)-transferase activity|amylo-(1,4 to 1,6)transglucosidase activity|plant branching enzyme|enzyme Q|branching enzyme activity|amylose isomerase activity|glucosan transglycosylase activity|branching glycosyltransferase activity|alpha-glucan-branching glycosyltransferase activity|amylo-(1,4->1,6)-transglycosylase activity|starch branching enzyme|1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity http://purl.obolibrary.org/obo/GO_0003844 CHEBI:88060 biolink:ChemicalSubstance ganglioside GP1(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88060 CHEBI:30779 biolink:ChemicalSubstance succinate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30779 CHEBI:30778 biolink:ChemicalSubstance gallic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30778 GO:0003841 biolink:MolecularActivity 1-acylglycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. Reactome:R-HSA-1482636|RHEA:19709|Reactome:R-HSA-75885|EC:2.3.1.51|Reactome:R-HSA-1482689|Reactome:R-HSA-1482539|Reactome:R-HSA-1482894|Reactome:R-HSA-1482548|Reactome:R-HSA-1482667|Reactome:R-HSA-1482547|MetaCyc:RXN-1623|Reactome:R-HSA-1482598|Reactome:R-HSA-8849345 go-plus.json 1-acyl-sn-glycerol-3-phosphate acyltransferase activity|lysophosphatidate acyltransferase activity|acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity|lysophosphatidic acid-acyltransferase activity|1-acyl-sn-glycerol 3-phosphate acyltransferase activity|1-acyl-sn-glycero-3-phosphate acyltransferase activity|1-acylglycerolphosphate acyltransferase activity|1-acylglycero-3-phosphate acyltransferase activity|1-acylglycerophosphate acyltransferase activity http://purl.obolibrary.org/obo/GO_0003841 NCBITaxon:3214 biolink:OrganismalEntity Bryopsida go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3214 CHEBI:30776 biolink:ChemicalSubstance hexanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30776 CHEBI:88065 biolink:ChemicalSubstance (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88065 CHEBI:30775 biolink:ChemicalSubstance fluoroacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30775 GO:0003840 biolink:MolecularActivity obsolete gamma-glutamyltransferase activity OBSOLETE. Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid. KEGG_REACTION:R04159|MetaCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.2 go-plus.json L-glutamyltransferase activity|alpha-glutamyl transpeptidase activity|gamma-glutamyl peptidyltransferase activity|(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity|gamma-GPT|L-gamma-glutamyl transpeptidase activity|gamma-glutamyl transpeptidase activity|gamma-GTP|glutamyl transpeptidase activity|gamma-GT|L-gamma-glutamyltransferase activity http://purl.obolibrary.org/obo/GO_0003840 CHEBI:88064 biolink:ChemicalSubstance (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88064 CHEBI:29785 biolink:ChemicalSubstance nitro group go-plus.json http://purl.obolibrary.org/obo/CHEBI_29785 chebi_ph7_3 GO:1904329 biolink:BiologicalProcess negative regulation of myofibroblast contraction Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction. go-plus.json inhibition of MF contraction|inhibition of MFB contraction|down-regulation of myofibroblast contraction|inhibition of myofibroblast contraction|down regulation of MFB contraction|down-regulation of MF contraction|negative regulation of MF contraction|downregulation of MFB contraction|down regulation of myofibroblast contraction|downregulation of MF contraction|down-regulation of MFB contraction|negative regulation of MFB contraction|down regulation of MF contraction|downregulation of myofibroblast contraction http://purl.obolibrary.org/obo/GO_1904329 CHEBI:88067 biolink:ChemicalSubstance (2E,5Z)-tetradecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88067 GO:1904328 biolink:BiologicalProcess regulation of myofibroblast contraction Any process that modulates the frequency, rate or extent of myofibroblast contraction. go-plus.json regulation of MFB contraction|regulation of MF contraction http://purl.obolibrary.org/obo/GO_1904328 CHEBI:88066 biolink:ChemicalSubstance dioctanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_88066 chebi_ph7_3 GO:1904327 biolink:BiologicalProcess protein localization to cytosolic proteasome complex A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex. go-plus.json protein localisation to cytosolic proteasome complex|protein localisation in cytosolic proteasome complex|protein localization in cytosolic proteasome complex http://purl.obolibrary.org/obo/GO_1904327 CHEBI:88069 biolink:ChemicalSubstance beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_88069 chebi_ph7_3 GO:1904326 biolink:BiologicalProcess negative regulation of circadian sleep/wake cycle, wakefulness Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness. go-plus.json down-regulation of circadian sleep/wake cycle, wakefulness|inhibition of circadian sleep/wake cycle, wakefulness|down regulation of circadian sleep/wake cycle, wakefulness|downregulation of circadian sleep/wake cycle, wakefulness http://purl.obolibrary.org/obo/GO_1904326 CHEBI:88068 biolink:ChemicalSubstance monosialomonoglycosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88068 GO:1904325 biolink:BiologicalProcess positive regulation of inhibitory G protein-coupled receptor phosphorylation Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation. go-plus.json up-regulation of inhibitory G-protein coupled receptor phosphorylation|positive regulation of inhibitory G-protein coupled receptor phosphorylation|upregulation of inhibitory G-protein coupled receptor phosphorylation|up regulation of inhibitory G-protein coupled receptor phosphorylation|activation of inhibitory G-protein coupled receptor phosphorylation http://purl.obolibrary.org/obo/GO_1904325 GO:0062121 biolink:BiologicalProcess linear element maturation The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements. go-plus.json LinE chromosome loading|LinE focus formation http://purl.obolibrary.org/obo/GO_0062121 GO:1904324 biolink:BiologicalProcess negative regulation of inhibitory G protein-coupled receptor phosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation. go-plus.json down-regulation of inhibitory G-protein coupled receptor phosphorylation|inhibition of inhibitory G-protein coupled receptor phosphorylation|negative regulation of inhibitory G-protein coupled receptor phosphorylation|down regulation of inhibitory G-protein coupled receptor phosphorylation|downregulation of inhibitory G-protein coupled receptor phosphorylation http://purl.obolibrary.org/obo/GO_1904324 GO:0062120 biolink:BiologicalProcess LinE complex assembly The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0062120 CHEBI:29780 biolink:ChemicalSubstance isochorismate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29780 chebi_ph7_3 GO:0062123 biolink:BiologicalProcess regulation of linear element maturation Any process that modulates the rate, frequency or extent of linear element maturation. go-plus.json http://purl.obolibrary.org/obo/GO_0062123 GO:1904323 biolink:BiologicalProcess regulation of inhibitory G protein-coupled receptor phosphorylation Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation. go-plus.json regulation of inhibitory G-protein coupled receptor phosphorylation http://purl.obolibrary.org/obo/GO_1904323 GO:0062122 biolink:MolecularActivity histone methyltransferase activity (H3-K37 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group onto lysine at position 37 of the histone H3 protein. go-plus.json histone lysine N-methyltransferase activity (H3-K37 specific) http://purl.obolibrary.org/obo/GO_0062122 GO:1904322 biolink:BiologicalProcess cellular response to forskolin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904322 GO:1904332 biolink:BiologicalProcess negative regulation of error-prone translesion synthesis Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis. go-plus.json down-regulation of mutagenic PRR|negative regulation of mutagenic PRR|inhibition of error-prone translesion synthesis|downregulation of mutagenic postreplication DNA repair|down-regulation of error-prone postreplication DNA repair|negative regulation of error-prone postreplication DNA repair|inhibition of mutagenic PRR|down regulation of mutagenic postreplication DNA repair|downregulation of error-prone postreplication DNA repair|inhibition of mutagenic postreplication DNA repair|down regulation of error-prone translesion synthesis|down regulation of error-prone postreplication DNA repair|downregulation of error-prone translesion synthesis|down regulation of mutagenic PRR|inhibition of error-prone postreplication DNA repair|downregulation of mutagenic PRR|down-regulation of mutagenic postreplication DNA repair|negative regulation of mutagenic postreplication DNA repair|down-regulation of error-prone translesion synthesis http://purl.obolibrary.org/obo/GO_1904332 GO:0062125 biolink:BiologicalProcess regulation of mitochondrial gene expression Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). go-plus.json http://purl.obolibrary.org/obo/GO_0062125 GO:1904331 biolink:BiologicalProcess regulation of error-prone translesion synthesis Any process that modulates the frequency, rate or extent of error-prone translesion synthesis. go-plus.json regulation of mutagenic postreplication DNA repair|regulation of error-prone postreplication DNA repair|regulation of mutagenic PRR http://purl.obolibrary.org/obo/GO_1904331 GO:0062124 biolink:MolecularActivity 4-hydroxybutyrate receptor activity Combining with 4-hydroxybutyrte to initiate a change in cell activity. go-plus.json gamma-hydroxybutyrate receptor activity http://purl.obolibrary.org/obo/GO_0062124 GO:0062127 biolink:BiologicalProcess fatty acid primary amide catabolic process The chemical reactions and pathways resulting in the breakdown of primary fatty amides. go-plus.json primary fatty amide catabolic process http://purl.obolibrary.org/obo/GO_0062127 GO:1904330 biolink:BiologicalProcess positive regulation of myofibroblast contraction Any process that activates or increases the frequency, rate or extent of myofibroblast contraction. go-plus.json up regulation of MF contraction|up regulation of MFB contraction|upregulation of myofibroblast contraction|positive regulation of MFB contraction|activation of MFB contraction|upregulation of MF contraction|up regulation of myofibroblast contraction|activation of myofibroblast contraction|up-regulation of MFB contraction|up-regulation of MF contraction|activation of MF contraction|upregulation of MFB contraction|up-regulation of myofibroblast contraction|positive regulation of MF contraction http://purl.obolibrary.org/obo/GO_1904330 GO:0062126 biolink:BiologicalProcess fatty acid primary amide metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides. go-plus.json primary fatty amide metabolic process http://purl.obolibrary.org/obo/GO_0062126 GO:0062129 biolink:CellularComponent chitin-based extracellular matrix Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet. go-plus.json chitin-based ECM http://purl.obolibrary.org/obo/GO_0062129 GO:0062128 biolink:CellularComponent MutSgamma complex A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5. go-plus.json Msh4-Msh5 complex http://purl.obolibrary.org/obo/GO_0062128 CHEBI:30772 biolink:ChemicalSubstance butyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30772 GO:0003847 biolink:MolecularActivity 1-alkyl-2-acetylglycerophosphocholine esterase activity Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate. EC:3.1.1.47|Reactome:R-HSA-8869206|RHEA:17777|MetaCyc:3.1.1.47-RXN go-plus.json LDL-PLA(2) activity|LDL-associated phospholipase A2|PAF 2-acylhydrolase activity|alkylacetyl-GPC:acetylhydrolase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity|LDL-associated phospholipase A(2) activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity|PAF acetylhydrolase activity|LDL-PLA2|platelet-activating factor acetylhydrolase activity|2-acetyl-1-alkylglycerophosphocholine esterase activity http://purl.obolibrary.org/obo/GO_0003847 goslim_chembl GO:0003846 biolink:MolecularActivity 2-acylglycerol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol. Reactome:R-HSA-6800334|EC:2.3.1.22|Reactome:R-HSA-5696448|RHEA:16741|MetaCyc:2-ACYLGLYCEROL-O-ACYLTRANSFERASE-RXN go-plus.json acylglycerol palmitoyltransferase activity|acyl-CoA:2-acylglycerol O-acyltransferase activity|monoglyceride acyltransferase activity|monoacylglycerol acyltransferase activity|acyl coenzyme A-monoglyceride acyltransferase activity http://purl.obolibrary.org/obo/GO_0003846 GO:0003849 biolink:MolecularActivity 3-deoxy-7-phosphoheptulonate synthase activity Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate. KEGG_REACTION:R01826|RHEA:14717|EC:2.5.1.54|MetaCyc:DAHPSYN-RXN go-plus.json 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate|2-dehydro-3-deoxy-phosphoheptonate aldolase activity|phospho-2-dehydro-3-deoxyheptonate aldolase activity|phospho-2-keto-3-deoxyheptonate aldolase activity|phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|D-erythrose-4-phosphate-lyase activity|KDPH synthetase activity|phospho-2-keto-3-deoxyheptonic aldolase activity|3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity|DS-Mn activity|phospho-2-keto-3-deoxyheptanoate aldolase activity|7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|DHAP synthase activity|KDPH synthase activity|DAH7-P synthase activity|3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity|DS-Co activity|D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity|2-dehydro-3-deoxyphosphoheptonate aldolase activity|phospho-2-oxo-3-deoxyheptonate aldolase activity|2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity|3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity|DAHP synthase activity|deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity http://purl.obolibrary.org/obo/GO_0003849 GO:0003848 biolink:MolecularActivity 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+). KEGG_REACTION:R03503|MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN|RHEA:11412|EC:2.7.6.3 go-plus.json 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity|6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity|2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity|H2-pteridine-CH2OH pyrophosphokinase activity|7,8-dihydroxymethylpterin-pyrophosphokinase activity|HPPK|hydroxymethyldihydropteridine pyrophosphokinase activity|ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity http://purl.obolibrary.org/obo/GO_0003848 goslim_chembl GO:0003810 biolink:MolecularActivity protein-glutamine gamma-glutamyltransferase activity Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links. Reactome:R-HSA-140851|Reactome:R-HSA-6810894|MetaCyc:2.3.2.13-RXN|RESID:AA0124|RHEA:54816|EC:2.3.2.13 go-plus.json fibrin stabilizing factor|glutaminylpeptide gamma-glutamyltransferase activity|polyamine transglutaminase activity|R-glutaminyl-peptide:amine gamma-glutamyl transferase activity|factor XIIIa|protein-glutamine:amine gamma-glutamyltransferase|transglutaminase activity|tissue transglutaminase|TGase activity|fibrinoligase activity http://purl.obolibrary.org/obo/GO_0003810 CHEBI:30749 biolink:ChemicalSubstance 4-chlorophenylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30749 CHEBI:30748 biolink:ChemicalSubstance 2,4-dichlorobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30748 CHEBI:88091 biolink:ChemicalSubstance 6-deoxy-6-sulfoglucono-1,5-lactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88091 chebi_ph7_3 GO:0003812 biolink:MolecularActivity obsolete alternative-complement-pathway C3/C5 convertase activity OBSOLETE. Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b. go-plus.json alternative complement pathway C3(C5) convertase activity|proenzyme factor B|alternative-complement-pathway C3/C5 convertase activity|complement factor B activity|C3b,Bb,CVF,Bb,C5 convertase activity|(CVF)-dependent glycine-rich-beta-glucoprotein|complement component C3/C5 convertase (alternative) activity|complement C 3(C 5) convertase (amplification)|(C3b)n,Bb|heat-labile factor|C5 convertase activity|cobra venom factor-dependent C3 convertase|C3 convertase activity|CVF,Bb|C3 proactivator|glycine-rich beta-glycoprotein|properdin factor B activity http://purl.obolibrary.org/obo/GO_0003812 CHEBI:30747 biolink:ChemicalSubstance 4-chlorobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30747 CHEBI:616459 biolink:ChemicalSubstance carbamimidoylazanium go-plus.json http://purl.obolibrary.org/obo/CHEBI_616459 CHEBI:88094 biolink:ChemicalSubstance 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88094 chebi_ph7_3 GO:0003811 biolink:MolecularActivity obsolete complement activity OBSOLETE. Any of a set of activities involved in the complement cascade. go-plus.json complement activity http://purl.obolibrary.org/obo/GO_0003811 CHEBI:30746 biolink:ChemicalSubstance benzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30746 CHEBI:88093 biolink:ChemicalSubstance 6-deoxy-6-sulfo-D-gluconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88093 chebi_ph7_3 CHEBI:88096 biolink:ChemicalSubstance N-hexanoylphytosphingosine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88096 chebi_ph7_3 CHEBI:30745 biolink:ChemicalSubstance phenylacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30745 CHEBI:30744 biolink:ChemicalSubstance oxaloacetic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30744 CHEBI:88095 biolink:ChemicalSubstance N-hexanoylphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_88095 chebi_ph7_3 CHEBI:88098 biolink:ChemicalSubstance 3beta,12alpha-dihydroxy-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88098 CHEBI:88097 biolink:ChemicalSubstance 7alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_88097 CHEBI:30742 biolink:ChemicalSubstance ethylene glycol go-plus.json http://purl.obolibrary.org/obo/CHEBI_30742 chebi_ph7_3 GO:0062150 biolink:MolecularActivity amorpha-4,11-diene 12-monooxygenase activity Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. RHEA:32999|EC:1.14.14.114 go-plus.json http://purl.obolibrary.org/obo/GO_0062150 CHEBI:88099 biolink:ChemicalSubstance D-3-sulfolactaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88099 chebi_ph7_3 GO:1904339 biolink:BiologicalProcess negative regulation of dopaminergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation. go-plus.json down regulation of dopaminergic neuron differentiation|downregulation of dopaminergic neuron differentiation|down-regulation of dopaminergic neuron differentiation|inhibition of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904339 CHEBI:29751 biolink:ChemicalSubstance (-)-quinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29751 chebi_ph7_3 GO:1904338 biolink:BiologicalProcess regulation of dopaminergic neuron differentiation Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1904338 GO:0062152 biolink:MolecularActivity mRNA (cytidine-5-)-methyltransferase activity Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine. RHEA:61464 go-plus.json mRNA (cytosine-5-)-methyltransferase activity http://purl.obolibrary.org/obo/GO_0062152 CHEBI:29754 biolink:ChemicalSubstance arsonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29754 GO:1904337 biolink:BiologicalProcess positive regulation of ductus arteriosus closure Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure. go-plus.json upregulation of ductus arteriosus closure|up regulation of ductus arteriosus closure|activation of ductus arteriosus closure|up-regulation of ductus arteriosus closure http://purl.obolibrary.org/obo/GO_1904337 GO:0062151 biolink:CellularComponent catalase complex A protein-containing complex that is capable of catalase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0062151 CHEBI:29753 biolink:ChemicalSubstance arsonite(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29753 GO:1904336 biolink:BiologicalProcess negative regulation of ductus arteriosus closure Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure. go-plus.json down regulation of ductus arteriosus closure|downregulation of ductus arteriosus closure|down-regulation of ductus arteriosus closure|inhibition of ductus arteriosus closure http://purl.obolibrary.org/obo/GO_1904336 GO:0062154 biolink:MolecularActivity N6-mAMP deaminase activity Catalysis of the reaction: H(+) + H2O + N6-methyl-AMP = IMP + methylamine. RHEA:16001 go-plus.json MAPDA http://purl.obolibrary.org/obo/GO_0062154 GO:1904335 biolink:BiologicalProcess regulation of ductus arteriosus closure Any process that modulates the frequency, rate or extent of ductus arteriosus closure. go-plus.json http://purl.obolibrary.org/obo/GO_1904335 GO:0062153 biolink:MolecularActivity C5-methylcytidine-containing RNA binding Binding to an RNA molecule modified by C5-methylcytidine. go-plus.json C5-methylcytosine-containing RNA binding http://purl.obolibrary.org/obo/GO_0062153 GO:1904334 biolink:BiologicalProcess heme import across plasma membrane The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json heme assimilation http://purl.obolibrary.org/obo/GO_1904334 GO:0062156 biolink:MolecularActivity mitochondrial ATP-gated potassium channel activity Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane. go-plus.json mitochondrial potassium channel activity|mitoK-ATP activity http://purl.obolibrary.org/obo/GO_0062156 CHEBI:29750 biolink:ChemicalSubstance 3-(indol-3-yl)pyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_29750 GO:1904333 biolink:BiologicalProcess positive regulation of error-prone translesion synthesis Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis. go-plus.json up regulation of mutagenic postreplication DNA repair|activation of error-prone postreplication DNA repair|up-regulation of error-prone translesion synthesis|positive regulation of error-prone postreplication DNA repair|up-regulation of mutagenic PRR|upregulation of mutagenic postreplication DNA repair|up regulation of error-prone postreplication DNA repair|upregulation of error-prone translesion synthesis|upregulation of mutagenic PRR|up-regulation of mutagenic postreplication DNA repair|upregulation of error-prone postreplication DNA repair|up regulation of error-prone translesion synthesis|activation of error-prone translesion synthesis|activation of mutagenic postreplication DNA repair|up regulation of mutagenic PRR|up-regulation of error-prone postreplication DNA repair|positive regulation of mutagenic PRR|activation of mutagenic PRR|positive regulation of mutagenic postreplication DNA repair http://purl.obolibrary.org/obo/GO_1904333 GO:0062155 biolink:CellularComponent curli secretion complex A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms. go-plus.json http://purl.obolibrary.org/obo/GO_0062155 GO:1904343 biolink:BiologicalProcess positive regulation of colon smooth muscle contraction Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction. go-plus.json up-regulation of colon smooth muscle contraction|upregulation of colon smooth muscle contraction|up regulation of colon smooth muscle contraction|activation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904343 GO:0062158 biolink:MolecularActivity chloride:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out). go-plus.json http://purl.obolibrary.org/obo/GO_0062158 GO:0062157 biolink:CellularComponent mitochondrial ATP-gated potassium channel complex A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0062157 GO:1904342 biolink:BiologicalProcess negative regulation of colon smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction. go-plus.json inhibition of colon smooth muscle contraction|down regulation of colon smooth muscle contraction|downregulation of colon smooth muscle contraction|down-regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904342 GO:1904341 biolink:BiologicalProcess regulation of colon smooth muscle contraction Any process that modulates the frequency, rate or extent of colon smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_1904341 GO:1904340 biolink:BiologicalProcess positive regulation of dopaminergic neuron differentiation Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. go-plus.json up-regulation of dopaminergic neuron differentiation|upregulation of dopaminergic neuron differentiation|up regulation of dopaminergic neuron differentiation|activation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904340 GO:0062159 biolink:CellularComponent contractile vacuole complex A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory. go-plus.json CVC http://purl.obolibrary.org/obo/GO_0062159 GO:0003818 biolink:MolecularActivity obsolete complement factor I activity OBSOLETE. Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage. go-plus.json complement C4bi|factor I|C3b/C4b inactivator activity|complement component C3b inactivator activity|complement C3b/C4b inactivator|C3bINA|complement C3b inactivator|complement C4b inactivator|complement factor I activity|conglutinogen-activating factor C|C3b inactivator activity http://purl.obolibrary.org/obo/GO_0003818 GO:0003817 biolink:MolecularActivity obsolete complement factor D activity OBSOLETE. Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF). go-plus.json adipsin|factor D|C3 convertase activator activity|properdin factor D esterase activity|factor D (complement)|complement factor D activity|C3 proactivator convertase activity http://purl.obolibrary.org/obo/GO_0003817 GO:0003819 biolink:MolecularActivity obsolete major histocompatibility complex antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json MHC protein|major histocompatibility complex antigen http://purl.obolibrary.org/obo/GO_0003819 GO:0003813 biolink:MolecularActivity obsolete classical-complement-pathway C3/C5 convertase activity OBSOLETE. Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b. go-plus.json C423|C4b,2a,3b|C4b,2a|complement C42|C42|complement C2 activity|C5 convertase activity|complement C3 convertase activity|C3 convertase activity|classical-complement-pathway C3/C5 convertase activity http://purl.obolibrary.org/obo/GO_0003813 GO:0003816 biolink:MolecularActivity obsolete complement component C1s activity OBSOLETE. Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond). go-plus.json C1s esterase activity|complement component C1s activity|complement C1s|C1 esterase activity|complement subcomponent C1s|activated complement C1s http://purl.obolibrary.org/obo/GO_0003816 GO:0003815 biolink:MolecularActivity obsolete complement component C1r activity OBSOLETE. Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42). go-plus.json C1r esterase activity|complement component C1r activity|complement subcomponent C1r|activated complement C1r http://purl.obolibrary.org/obo/GO_0003815 UBERON:2005260 biolink:AnatomicalEntity fenestrated capillary Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse go-plus.json fenestrated capillary vessel|fenestrated blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_2005260 GO:0003821 biolink:MolecularActivity obsolete class II major histocompatibility complex antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json class II major histocompatibility complex antigen http://purl.obolibrary.org/obo/GO_0003821 CHEBI:88081 biolink:ChemicalSubstance fatty acid anion 23:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_88081 GO:0003820 biolink:MolecularActivity obsolete class I major histocompatibility complex antigen OBSOLETE. (Was not defined before being made obsolete). go-plus.json class I major histocompatibility complex antigen http://purl.obolibrary.org/obo/GO_0003820 CHEBI:88080 biolink:ChemicalSubstance (5Z)-3-oxotetradecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88080 GO:0003823 biolink:MolecularActivity antigen binding Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. go-plus.json immunoglobulin|opsonin activity|B cell receptor activity|antibody http://purl.obolibrary.org/obo/GO_0003823 goslim_chembl|goslim_pir CHEBI:88083 biolink:ChemicalSubstance (3E)-tetradecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88083 GO:0003822 biolink:MolecularActivity obsolete MHC-interacting protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json MHC-interacting protein http://purl.obolibrary.org/obo/GO_0003822 CHEBI:88084 biolink:ChemicalSubstance (2E,4E)-tetradecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88084 CHEBI:30754 biolink:ChemicalSubstance anthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30754 CHEBI:88087 biolink:ChemicalSubstance (3S,7Z)-3-hydroxyhexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88087 CHEBI:88086 biolink:ChemicalSubstance (2E,7Z)-hexadecadienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88086 CHEBI:30753 biolink:ChemicalSubstance 4-aminobenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30753 CHEBI:88089 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88089 chebi_ph7_3 CHEBI:88088 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88088 chebi_ph7_3 GO:0062141 biolink:CellularComponent nuclear exosome targeting complex A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts. go-plus.json NEXT complex http://purl.obolibrary.org/obo/GO_0062141 GO:1904349 biolink:BiologicalProcess positive regulation of small intestine smooth muscle contraction Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction. go-plus.json up regulation of small intestine smooth muscle contraction|activation of small intestine smooth muscle contraction|up-regulation of small intestine smooth muscle contraction|upregulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904349 GO:0062140 biolink:CellularComponent hyphae septin collar A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell. go-plus.json septin collar of invasive hyphae http://purl.obolibrary.org/obo/GO_0062140 GO:1904348 biolink:BiologicalProcess negative regulation of small intestine smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction. go-plus.json down regulation of small intestine smooth muscle contraction|downregulation of small intestine smooth muscle contraction|down-regulation of small intestine smooth muscle contraction|inhibition of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904348 GO:1904347 biolink:BiologicalProcess regulation of small intestine smooth muscle contraction Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_1904347 GO:0062143 biolink:BiologicalProcess L-propargylglycine biosynthetic process The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0062143 GO:1904346 biolink:BiologicalProcess positive regulation of gastric mucosal blood circulation Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation. go-plus.json activation of stomach mucosal blood circulation|positive regulation of stomach mucosal blood circulation|up-regulation of gastric mucosal blood circulation|upregulation of gastric mucosal blood circulation|up-regulation of stomach mucosal blood circulation|up regulation of gastric mucosal blood circulation|upregulation of stomach mucosal blood circulation|activation of gastric mucosal blood circulation|up regulation of stomach mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904346 GO:0062142 biolink:BiologicalProcess L-beta-ethynylserine biosynthetic process The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria. go-plus.json http://purl.obolibrary.org/obo/GO_0062142 GO:1904345 biolink:BiologicalProcess negative regulation of gastric mucosal blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation. go-plus.json inhibition of gastric mucosal blood circulation|negative regulation of stomach mucosal blood circulation|down-regulation of stomach mucosal blood circulation|inhibition of stomach mucosal blood circulation|down regulation of gastric mucosal blood circulation|downregulation of gastric mucosal blood circulation|down regulation of stomach mucosal blood circulation|down-regulation of gastric mucosal blood circulation|downregulation of stomach mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904345 GO:0062145 biolink:MolecularActivity L-propargylglycine--L-glutamate ligase activity Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate. RHEA:59896 go-plus.json http://purl.obolibrary.org/obo/GO_0062145 GO:0062144 biolink:MolecularActivity L-propargylglycine synthase activity Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H(+) + L-propargylglycine. RHEA:59892 go-plus.json http://purl.obolibrary.org/obo/GO_0062144 GO:1904344 biolink:BiologicalProcess regulation of gastric mucosal blood circulation Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation. go-plus.json regulation of stomach mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904344 GO:0062147 biolink:MolecularActivity L-lysine 4-chlorinase activity Catalysis of the reaction: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate. RHEA:59884 go-plus.json http://purl.obolibrary.org/obo/GO_0062147 GO:1904354 biolink:BiologicalProcess negative regulation of telomere capping Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping. go-plus.json down-regulation of telomere capping|down-regulation of telomere end protection|negative regulation of telomere end protection|inhibition of telomere end protection|downregulation of telomere capping|down regulation of telomere capping|inhibition of telomere capping|down regulation of telomere end protection|downregulation of telomere end protection http://purl.obolibrary.org/obo/GO_1904354 GO:0086103 biolink:BiologicalProcess G protein-coupled receptor signaling pathway involved in heart process An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. go-plus.json G-protein coupled receptor signaling pathway involved in heart process|GPCR signaling pathway involved in heart process|GPCR signaling pathway involved in cardiac process|G-protein coupled receptor signalling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086103 GO:0062146 biolink:MolecularActivity 4-chloro-allylglycine synthase activity Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+). RHEA:59888 go-plus.json http://purl.obolibrary.org/obo/GO_0062146 GO:1904353 biolink:BiologicalProcess regulation of telomere capping Any process that modulates the frequency, rate or extent of telomere capping. go-plus.json regulation of telomere end protection http://purl.obolibrary.org/obo/GO_1904353 GO:0086102 biolink:BiologicalProcess adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate A G protein-coupled acetylcholine receptor signaling pathway that contributes to an decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate. go-plus.json Gi-coupled G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of funny current|AC-inhibiting muscarinic receptor signaling pathway involved in negative regulation of heart rate|adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate via inhibition of adenylate cyclase activity|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of If channel http://purl.obolibrary.org/obo/GO_0086102 GO:1904352 biolink:BiologicalProcess positive regulation of protein catabolic process in the vacuole Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. go-plus.json activation of vacuolar protein catabolic process|activation of protein catabolic process in the vacuole|positive regulation of vacuolar protein breakdown|up regulation of vacuolar protein catabolism|positive regulation of vacuolar protein catabolism|up regulation of vacuolar protein breakdown|positive regulation of vacuolar protein catabolic process|up regulation of vacuolar protein catabolic process|upregulation of vacuolar protein degradation|activation of vacuolar protein catabolism|up regulation of protein catabolic process in the vacuole|upregulation of vacuolar protein breakdown|up-regulation of vacuolar protein catabolism|up-regulation of vacuolar protein degradation|upregulation of vacuolar protein catabolic process|up-regulation of vacuolar protein breakdown|upregulation of protein catabolic process in the vacuole|upregulation of vacuolar protein catabolism|activation of vacuolar protein degradation|up-regulation of vacuolar protein catabolic process|activation of vacuolar protein breakdown|positive regulation of vacuolar protein degradation|up regulation of vacuolar protein degradation|up-regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_1904352 GO:0062149 biolink:BiologicalProcess detection of stimulus involved in sensory perception of pain The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0062149 GO:0086101 biolink:BiologicalProcess endothelin receptor signaling pathway involved in heart process An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart. go-plus.json endothelin receptor signalling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086101 GO:1904351 biolink:BiologicalProcess negative regulation of protein catabolic process in the vacuole Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. go-plus.json downregulation of vacuolar protein degradation|down-regulation of vacuolar protein catabolic process|negative regulation of vacuolar protein catabolic process|down regulation of vacuolar protein degradation|downregulation of vacuolar protein breakdown|down-regulation of protein catabolic process in the vacuole|negative regulation of vacuolar protein catabolism|down-regulation of vacuolar protein catabolism|downregulation of vacuolar protein catabolic process|down regulation of vacuolar protein breakdown|inhibition of vacuolar protein degradation|down regulation of vacuolar protein catabolic process|downregulation of protein catabolic process in the vacuole|inhibition of vacuolar protein breakdown|inhibition of vacuolar protein catabolism|down regulation of protein catabolic process in the vacuole|inhibition of protein catabolic process in the vacuole|inhibition of vacuolar protein catabolic process|down-regulation of vacuolar protein degradation|negative regulation of vacuolar protein degradation|down regulation of vacuolar protein catabolism|negative regulation of vacuolar protein breakdown|down-regulation of vacuolar protein breakdown|downregulation of vacuolar protein catabolism http://purl.obolibrary.org/obo/GO_1904351 GO:0086100 biolink:BiologicalProcess endothelin receptor signaling pathway A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json endothelin signaling pathway http://purl.obolibrary.org/obo/GO_0086100 GO:0062148 biolink:MolecularActivity L-gamma-glutamyl-L-propargylglycine hydroxylase activity Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate. RHEA:59900 go-plus.json http://purl.obolibrary.org/obo/GO_0062148 NCBITaxon:2743711 biolink:OrganismalEntity Danioninae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2743711 GO:1904350 biolink:BiologicalProcess regulation of protein catabolic process in the vacuole Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. go-plus.json regulation of vacuolar protein degradation|regulation of vacuolar protein breakdown|regulation of vacuolar protein catabolic process|regulation of vacuolar protein catabolism http://purl.obolibrary.org/obo/GO_1904350 CHEBI:15138 biolink:ChemicalSubstance sulfide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_15138 GO:0003829 biolink:MolecularActivity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R. Reactome:R-HSA-914018|RHEA:18705|Reactome:R-HSA-914012|EC:2.4.1.102|MetaCyc:2.4.1.102-RXN go-plus.json O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity|uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity|beta6-N-acetylglucosaminyltransferase activity|core 2 acetylglucosaminyltransferase activity|beta(6)-N-acetylglucosaminyltransferase activity|core 6-beta-GlcNAc-transferase A|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0003829 GO:0003828 biolink:MolecularActivity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R. Reactome:R-HSA-422454|EC:2.4.99.8|Reactome:R-HSA-1022133|MetaCyc:2.4.99.8-RXN|Reactome:R-HSA-4084978|RHEA:19313 go-plus.json GD3 synthase activity|SAT-2|ganglioside GD3 synthase activity|CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity|CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-ganglioside GM3|ganglioside GD3 synthetase sialyltransferase activity|alpha-2,8-sialyltransferase activity|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity|CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity http://purl.obolibrary.org/obo/GO_0003828 CHEBI:30751 biolink:ChemicalSubstance formic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_30751 GO:0003825 biolink:MolecularActivity alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate. EC:2.4.1.15|RHEA:18889|MetaCyc:TREHALOSE6PSYN-RXN go-plus.json trehalose-phosphate synthase activity|UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|uridine diphosphoglucose phosphate glucosyltransferase activity|UDP-glucose-glucose-phosphate glucosyltransferase activity|trehalosephosphate-UDP glucosyl transferase activity|alpha,alpha-trehalose phosphate synthase (UDP-forming)|trehalose-P synthetase activity|phosphotrehalose-uridine diphosphate transglucosylase activity|trehalose 6-phosphate synthase activity|trehalosephosphate-UDP glucosyltransferase activity|trehalose phosphate synthetase activity|UDP-glucose-glucosephosphate glucosyltransferase activity|transglucosylase activity|UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|trehalose-phosphate synthetase activity|UDPglucose-glucose-phosphate glucosyltransferase activity|trehalose phosphate synthase activity|trehalose phosphate-uridine diphosphate glucosyltransferase activity|trehalose 6-phosphate synthetase activity http://purl.obolibrary.org/obo/GO_0003825 GO:0003824 biolink:MolecularActivity catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Wikipedia:Enzyme go-plus.json enzyme activity http://purl.obolibrary.org/obo/GO_0003824 goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_pir|goslim_plant|goslim_metagenomics GO:0003827 biolink:MolecularActivity alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP. RHEA:11456|Reactome:R-HSA-964768|KEGG_REACTION:R05983|MetaCyc:2.4.1.101-RXN|EC:2.4.1.101 go-plus.json GNTI activity|alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity|uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|GnTI|N-acetylglucosaminyltransferase I activity|alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity http://purl.obolibrary.org/obo/GO_0003827 CHEBI:88090 biolink:ChemicalSubstance (7Z)-3-oxohexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88090 GO:0003826 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003826 CHEBI:29739 biolink:ChemicalSubstance 5alpha,9beta,10alpha-labda-8(20),13-dien-15-yl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29739 NCBITaxon:3245 biolink:OrganismalEntity Selaginellaceae go-plus.json spike mosses http://purl.obolibrary.org/obo/NCBITaxon_3245 NCBITaxon:3244 biolink:OrganismalEntity Selaginellales go-plus.json spike mosses http://purl.obolibrary.org/obo/NCBITaxon_3244 GO:0062170 biolink:BiologicalProcess lutein metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein. go-plus.json lutein metabolism http://purl.obolibrary.org/obo/GO_0062170 NCBITaxon:3246 biolink:OrganismalEntity Selaginella go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_3246 GO:0062172 biolink:BiologicalProcess lutein catabolic process The chemical reactions and pathways resulting in the breakdown of lutein. go-plus.json lutein catabolism|lutein degradation|lutein breakdown http://purl.obolibrary.org/obo/GO_0062172 GO:0062171 biolink:BiologicalProcess lutein biosynthetic process The chemical reactions and pathways resulting in the formation of lutein. go-plus.json lutein formation|lutein biosynthesis|lutein anabolism http://purl.obolibrary.org/obo/GO_0062171 GO:0062174 biolink:BiologicalProcess brexanolone biosynthetic process The chemical reactions and pathways resulting in the formation of brexanolone. go-plus.json allotetrahydroprogesterone biosynthesis|allotetrahydroprogesterone biosynthetic process|brexanolone biosynthesis|allotetrahydroprogesterone anabolism|brexanolone anabolism|allotetrahydroprogesterone synthesis|brexanolone synthesis|allopregnanolone biosynthetic process|allopregnanolone biosynthesis|allopregnanolone anabolism|allopregnanolone synthesis http://purl.obolibrary.org/obo/GO_0062174 GO:1904359 biolink:BiologicalProcess regulation of spore germination Any process that modulates the frequency, rate or extent of spore germination. go-plus.json modulation of spore germination on or near host http://purl.obolibrary.org/obo/GO_1904359 GO:0062173 biolink:BiologicalProcess brexanolone metabolic process The chemical reactions and pathways by which living organisms transform brexanolone. go-plus.json allotetrahydroprogesterone metabolism|brexanolone metabolism|allopregnanolone metabolism|allopregnanolone metabolic process|allotetrahydroprogesterone metabolic process http://purl.obolibrary.org/obo/GO_0062173 GO:0062176 biolink:BiologicalProcess R-loop disassembly A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. go-plus.json http://purl.obolibrary.org/obo/GO_0062176 GO:1904358 biolink:BiologicalProcess positive regulation of telomere maintenance via telomere lengthening Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening. go-plus.json upregulation of telomere maintenance via telomere lengthening|up regulation of telomere maintenance via telomere lengthening|activation of telomere maintenance via telomere lengthening|up-regulation of telomere maintenance via telomere lengthening http://purl.obolibrary.org/obo/GO_1904358 GO:0062175 biolink:BiologicalProcess brexanolone catabolic process The chemical reactions and pathways resulting in the breakdown of brexanolone. go-plus.json allopregnanolone catabolism|allopregnanolone degradation|allopregnanolone breakdown|allotetrahydroprogesterone degradation|brexanolone degradation|allopregnanolone catabolic process|brexanolone breakdown|allotetrahydroprogesterone breakdown|brexanolone catabolism|allotetrahydroprogesterone catabolic process|allotetrahydroprogesterone catabolism http://purl.obolibrary.org/obo/GO_0062175 GO:1904357 biolink:BiologicalProcess negative regulation of telomere maintenance via telomere lengthening Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening. go-plus.json down regulation of telomere maintenance via telomere lengthening|downregulation of telomere maintenance via telomere lengthening|down-regulation of telomere maintenance via telomere lengthening|inhibition of telomere maintenance via telomere lengthening http://purl.obolibrary.org/obo/GO_1904357 GO:1904356 biolink:BiologicalProcess regulation of telomere maintenance via telomere lengthening Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening. go-plus.json http://purl.obolibrary.org/obo/GO_1904356 GO:0062178 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0062178 GO:1904355 biolink:BiologicalProcess positive regulation of telomere capping Any process that activates or increases the frequency, rate or extent of telomere capping. go-plus.json activation of telomere end protection|positive regulation of telomere end protection|up regulation of telomere capping|up-regulation of telomere end protection|upregulation of telomere end protection|upregulation of telomere capping|up-regulation of telomere capping|up regulation of telomere end protection|activation of telomere capping http://purl.obolibrary.org/obo/GO_1904355 GO:0062177 biolink:BiologicalProcess radial spoke assembly The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0062177 GO:1904365 biolink:BiologicalProcess regulation of chemokinesis Any process that modulates the frequency, rate or extent of chemokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_1904365 GO:1904364 biolink:BiologicalProcess positive regulation of calcitonin secretion Any process that activates or increases the frequency, rate or extent of calcitonin secretion. go-plus.json up regulation of calcitonin secretion|upregulation of calcitonin secretion|up-regulation of calcitonin secretion|activation of calcitonin secretion http://purl.obolibrary.org/obo/GO_1904364 GO:0062179 biolink:MolecularActivity vitamin D 23-hydroxylase activity Catalysis of the hydroxylation of C-23 of any form of vitamin D. go-plus.json http://purl.obolibrary.org/obo/GO_0062179 GO:1904363 biolink:BiologicalProcess negative regulation of calcitonin secretion Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion. go-plus.json downregulation of calcitonin secretion|down regulation of calcitonin secretion|inhibition of calcitonin secretion|down-regulation of calcitonin secretion http://purl.obolibrary.org/obo/GO_1904363 GO:1904362 biolink:BiologicalProcess regulation of calcitonin secretion Any process that modulates the frequency, rate or extent of calcitonin secretion. go-plus.json http://purl.obolibrary.org/obo/GO_1904362 GO:1904361 biolink:BiologicalProcess positive regulation of spore germination Any process that activates or increases the frequency, rate or extent of spore germination. go-plus.json upregulation of spore germination|up regulation of spore germination|activation of spore germination|positive regulation of spore germination on or near host|up-regulation of spore germination http://purl.obolibrary.org/obo/GO_1904361 GO:1904360 biolink:BiologicalProcess negative regulation of spore germination Any process that stops, prevents or reduces the frequency, rate or extent of spore germination. go-plus.json down regulation of spore germination|downregulation of spore germination|down-regulation of spore germination|inhibition of spore germination|negative regulation of spore germination on or near host http://purl.obolibrary.org/obo/GO_1904360 CHEBI:29749 biolink:ChemicalSubstance ferulate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29749 chebi_ph7_3 CHEBI:30737 biolink:ChemicalSubstance trichloromethyl(.) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30737 chebi_ph7_3 CHEBI:29748 biolink:ChemicalSubstance chorismate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_29748 chebi_ph7_3 GO:0003801 biolink:MolecularActivity obsolete blood coagulation factor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json blood coagulation factor activity http://purl.obolibrary.org/obo/GO_0003801 GO:0003800 biolink:MolecularActivity obsolete antiviral response protein activity OBSOLETE. A protein involved in an antiviral response. go-plus.json antiviral response protein activity http://purl.obolibrary.org/obo/GO_0003800 CHEBI:29745 biolink:ChemicalSubstance barbiturate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29745 CHEBI:29744 biolink:ChemicalSubstance lithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29744 chebi_ph7_3 CHEBI:29747 biolink:ChemicalSubstance cholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29747 chebi_ph7_3 CHEBI:29746 biolink:ChemicalSubstance glycocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29746 chebi_ph7_3 GO:0062161 biolink:BiologicalProcess regulation of pyocyanine biosynthetic process Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process. go-plus.json regulation of pyocyanin biosynthetic process http://purl.obolibrary.org/obo/GO_0062161 GO:0062160 biolink:CellularComponent spongiome A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory. go-plus.json http://purl.obolibrary.org/obo/GO_0062160 GO:0062163 biolink:BiologicalProcess pseudohyphal septin ring assembly The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection. go-plus.json http://purl.obolibrary.org/obo/GO_0062163 CHEBI:29743 biolink:ChemicalSubstance 3-oxododecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_29743 chebi_ph7_3 GO:0062162 biolink:BiologicalProcess positive regulation of pyocyanine biosynthetic process Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process. go-plus.json positive regulation of pyocyanin biosynthetic process http://purl.obolibrary.org/obo/GO_0062162 GO:0062165 biolink:BiologicalProcess positive regulation of pseudohyphal septin ring assembly Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation. go-plus.json http://purl.obolibrary.org/obo/GO_0062165 GO:1904369 biolink:BiologicalProcess positive regulation of sclerenchyma cell differentiation Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation. go-plus.json up-regulation of sclerenchyma cell differentiation|upregulation of sclerenchyma cell differentiation|up regulation of sclerenchyma cell differentiation http://purl.obolibrary.org/obo/GO_1904369 GO:1904368 biolink:BiologicalProcess regulation of sclerenchyma cell differentiation Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_1904368 GO:0062164 biolink:BiologicalProcess regulation of pseudohyphal septin ring assembly Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0062164 GO:1904367 biolink:BiologicalProcess positive regulation of chemokinesis Any process that activates or increases the frequency, rate or extent of chemokinesis. go-plus.json upregulation of chemokinesis|up-regulation of chemokinesis|activation of chemokinesis|up regulation of chemokinesis http://purl.obolibrary.org/obo/GO_1904367 GO:0062167 biolink:CellularComponent complement component C1q complex A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning. go-plus.json C1q|Complement 1q http://purl.obolibrary.org/obo/GO_0062167 GO:1904366 biolink:BiologicalProcess negative regulation of chemokinesis Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis. go-plus.json inhibition of chemokinesis|down-regulation of chemokinesis|downregulation of chemokinesis|down regulation of chemokinesis http://purl.obolibrary.org/obo/GO_1904366 GO:0062166 biolink:BiologicalProcess negative regulation of pseudohyphal septin ring assembly Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0062166 GO:1904376 biolink:BiologicalProcess negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. go-plus.json down-regulation of protein localization to cell periphery|downregulation of protein localization to cell periphery|down regulation of protein localization to cell periphery|inhibition of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1904376 GO:0062169 biolink:BiologicalProcess regulation of plus-end directed microtubule sliding Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding. go-plus.json http://purl.obolibrary.org/obo/GO_0062169 GO:0062168 biolink:BiologicalProcess negative regulation of plus-end directed microtubule sliding Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding. go-plus.json http://purl.obolibrary.org/obo/GO_0062168 GO:1904375 biolink:BiologicalProcess regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to cell periphery. go-plus.json http://purl.obolibrary.org/obo/GO_1904375 GO:1904374 biolink:BiologicalProcess cellular response to kainic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904374 GO:1904373 biolink:BiologicalProcess response to kainic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904373 GO:1904372 biolink:BiologicalProcess positive regulation of protein localization to actin cortical patch Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch. go-plus.json positive regulation of protein localisation to actin cortical patch|up regulation of protein localisation to actin cortical patch|up regulation of protein localization to actin cortical patch|upregulation of protein localisation to actin cortical patch|upregulation of protein localization to actin cortical patch|up-regulation of protein localisation to actin cortical patch|activation of protein localisation to actin cortical patch|up-regulation of protein localization to actin cortical patch|activation of protein localization to actin cortical patch http://purl.obolibrary.org/obo/GO_1904372 GO:1904371 biolink:BiologicalProcess negative regulation of protein localization to actin cortical patch Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch. go-plus.json down-regulation of protein localization to actin cortical patch|downregulation of protein localisation to actin cortical patch|down regulation of protein localisation to actin cortical patch|inhibition of protein localisation to actin cortical patch|downregulation of protein localization to actin cortical patch|down regulation of protein localization to actin cortical patch|inhibition of protein localization to actin cortical patch|negative regulation of protein localisation to actin cortical patch|down-regulation of protein localisation to actin cortical patch http://purl.obolibrary.org/obo/GO_1904371 GO:1904370 biolink:BiologicalProcess regulation of protein localization to actin cortical patch Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch. go-plus.json regulation of protein localisation to actin cortical patch http://purl.obolibrary.org/obo/GO_1904370 GO:0003807 biolink:MolecularActivity obsolete plasma kallikrein activity OBSOLETE. Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin. go-plus.json plasma kallikrein activity|glumorin|panceatic kallikrein|onokrein P|urokallikrein|padreatin|depot-padutin|dilminal D|kallikrein I|serum kallikrein activity|kininogenase|padutin|kallidinogenase|kininogenin activity|kallikrein|kallikrein II|callicrein|urinary kallikrein http://purl.obolibrary.org/obo/GO_0003807 GO:0003806 biolink:MolecularActivity obsolete coagulation factor XIIa activity OBSOLETE. Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa. go-plus.json prealbumin activator|kallikreinogen activator|hageman factor activity|blood-coagulation factor XIIabeta|hageman factor beta-fragment|blood-coagulation factor XIIf|blood coagulation factor XII activity|activated beta blood-coagulation factor XII|coagulation factor XIIa activity|hageman factor fragment HFf|hageman factor (activated)|prekallikrein activator http://purl.obolibrary.org/obo/GO_0003806 GO:0003809 biolink:MolecularActivity obsolete thrombin activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B. go-plus.json tropostasin|beta-thrombin|E thrombin|thrombase activity|thrombin-C|activated blood-coagulation factor II|topical|blood-coagulation factor IIa|fibrinogenase activity|thrombofort|gamma-thrombin|factor IIa|thrombin activity http://purl.obolibrary.org/obo/GO_0003809 GO:0003808 biolink:MolecularActivity obsolete protein C (activated) activity OBSOLETE. Catalysis of the degradation of blood coagulation factors Va and VIIIa. go-plus.json GSAPC|blood-coagulation factor XIVa|autoprothrombin IIA activity|protein Ca|activated protein C|activated blood coagulation factor XIV activity|protein C (activated) activity|autoprothrombin II-A http://purl.obolibrary.org/obo/GO_0003808 GO:0003803 biolink:MolecularActivity obsolete coagulation factor IXa activity OBSOLETE. Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa. go-plus.json Christmas factor activity|coagulation factor IXa activity|activated christmas factor|activated blood coagulation factor XI|autoprothrombin II|blood platelet cofactor II|blood coagulation factor IX activity|activated blood-coagulation factor IX|blood-coagulation factor IXa http://purl.obolibrary.org/obo/GO_0003803 GO:0003802 biolink:MolecularActivity obsolete coagulation factor VIIa activity OBSOLETE. Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta. go-plus.json blood coagulation factor VII activity|blood-coagulation factor VIIa|activated blood coagulation factor VII|coagulation factor VIIa activity http://purl.obolibrary.org/obo/GO_0003802 GO:0003805 biolink:MolecularActivity obsolete coagulation factor XIa activity OBSOLETE. Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa. go-plus.json blood-coagulation factor XIa|coagulation factor XIa activity|activated plasma thromboplastin antecedent|blood coagulation factor XI activity|activated blood-coagulation factor XI|plasma thromboplastin antecedent activity http://purl.obolibrary.org/obo/GO_0003805 GO:0003804 biolink:MolecularActivity obsolete coagulation factor Xa activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa). go-plus.json thrombokinase activity|thromboplastin|plasma thromboplastin|Stuart factor|activated blood-coagulation factor X|factor Xa|activated factor X|prothrombinase activity|blood coagulation factor X activity|Stuart factor activity|prothrombase activity|coagulation factor Xa activity|autoprothrombin C|activated Stuart-Prower factor http://purl.obolibrary.org/obo/GO_0003804 CHEBI:29715 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_29715 GO:0062192 biolink:MolecularActivity L-rhamnose mutarotase activity Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose. EC:5.1.3.32|RHEA:25584 go-plus.json http://purl.obolibrary.org/obo/GO_0062192 GO:0062191 biolink:BiologicalProcess galactoxylomannan biosynthetic process The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals. go-plus.json galactoxylomannan anabolism|glucuronoxylomannogalactan biosynthetic process|galactoxylomannan synthesis|GalXM biosynthetic process|galactoxylomannan formation|galactoxylomannan biosynthesis http://purl.obolibrary.org/obo/GO_0062191 GO:0062194 biolink:CellularComponent cytoplasmic microtubule minus-end A microtubule minus end that is part of a cytoplasmic microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0062194 GO:0062193 biolink:MolecularActivity D-ribose pyranase activity Catalysis of the reaction: beta-D-ribopyranose = beta-D-ribofuranose. RHEA:25432|EC:5.4.99.62 go-plus.json http://purl.obolibrary.org/obo/GO_0062193 GO:0062196 biolink:BiologicalProcess regulation of lysosome size Any process that modulates the size of a lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0062196 GO:0062195 biolink:BiologicalProcess microtubule bundle maintenance The organization process that preserves a microtubule bundle in a stable functional or structural state. go-plus.json http://purl.obolibrary.org/obo/GO_0062195 GO:0062198 biolink:CellularComponent obsolete rDNA replication pause site heterochromatin OBSOLETE. A region of heterochromatin associated with sites in rDNA repeats where replication forks pause. go-plus.json http://purl.obolibrary.org/obo/GO_0062198 GO:1904379 biolink:BiologicalProcess protein localization to cytosolic proteasome complex involved in ERAD pathway Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation. go-plus.json protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localization in cytosolic proteasome complex involved in ERAD pathway|protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localization to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation in cytosolic proteasome complex involved in ERAD pathway|protein localisation in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation to cytosolic proteasome complex involved in ERAD pathway|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation http://purl.obolibrary.org/obo/GO_1904379 GO:0062197 biolink:BiologicalProcess cellular response to chemical stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress. go-plus.json http://purl.obolibrary.org/obo/GO_0062197 GO:1904378 biolink:BiologicalProcess maintenance of unfolded protein involved in ERAD pathway Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome. go-plus.json maintenance of unfolded protein during ERAD|maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway|chaperone holdase activity|ERAD chaperone-like activity|holdase activity|maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation|maintenance of unfolded protein involved in ER-associated degradation pathway http://purl.obolibrary.org/obo/GO_1904378 GO:0062199 biolink:CellularComponent chromosome, centromeric inner repeat region The portion of the centromeric region of a chromosome that contains the inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm. go-plus.json chromosome, centric outer repeat region http://purl.obolibrary.org/obo/GO_0062199 GO:1904377 biolink:BiologicalProcess positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. go-plus.json up regulation of protein localization to cell periphery|upregulation of protein localization to cell periphery|activation of protein localization to cell periphery|up-regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1904377 GO:1904387 biolink:BiologicalProcess cellular response to L-phenylalanine derivative Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904387 GO:1904386 biolink:BiologicalProcess response to L-phenylalanine derivative Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904386 GO:1904385 biolink:BiologicalProcess cellular response to angiotensin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen. go-plus.json http://purl.obolibrary.org/obo/GO_1904385 GO:1904384 biolink:BiologicalProcess cellular response to sodium phosphate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904384 GO:1904383 biolink:BiologicalProcess response to sodium phosphate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904383 GO:1904382 biolink:BiologicalProcess mannose trimming involved in glycoprotein ERAD pathway The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD). go-plus.json glycoprotein mannose trimming involved in gpERAD|glycoprotein mannose trimming involved in glycoprotein ERAD|protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation|protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway|glycoprotein mannose trimming involved in ER-associated glycoprotein degradation|glycoprotein mannose trimming involved in glycoprotein ERAD pathway|protein alpha-1,2-demannosylation involved in gpERAD|mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process|protein alpha-1,2-demannosylation involved in glycoprotein ERAD http://purl.obolibrary.org/obo/GO_1904382 GO:1904381 biolink:BiologicalProcess Golgi apparatus mannose trimming Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus. go-plus.json glycoprotein mannose trimming in Golgi complex|glycoprotein mannose trimming in Golgi ribbon|protein alpha-1,2-demannosylation in Golgi apparatus|mannose trimming in cis-Golgi|glycoprotein mannose trimming in Golgi apparatus|mannose trimming in Golgi apparatus|protein alpha-1,2-demannosylation in Golgi ribbon|mannose trimming in Golgi|protein alpha-1,2-demannosylation in Golgi complex http://purl.obolibrary.org/obo/GO_1904381 GO:1904380 biolink:BiologicalProcess endoplasmic reticulum mannose trimming Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC). go-plus.json protein alpha-1,2-demannosylation in ER|protein alpha-1,2-demannosylation in endoplasmic reticulum|protein alpha-1,2-demannosylation in ER-derived quality control compartment|glycoprotein mannose trimming in ER-derived quality control compartment|protein alpha-1,2-demannosylation in ERQC|protein alpha-1,2-demannosylation in ER quality control compartment|glycoprotein mannose trimming in ERQC|ER mannose trimming|protein alpha-1,2-demannosylation in endoplasmic reticulum quality control compartment|glycoprotein mannose trimming in ER quality control compartment|glycoprotein mannose trimming in endoplasmic reticulum quality control compartment|ER protein alpha-1,2-demannosylation http://purl.obolibrary.org/obo/GO_1904380 CHEBI:29726 biolink:ChemicalSubstance dTDP-6-deoxy-alpha-D-allose go-plus.json http://purl.obolibrary.org/obo/CHEBI_29726 CHEBI:29728 biolink:ChemicalSubstance dTDP-alpha-D-mycaminose go-plus.json http://purl.obolibrary.org/obo/CHEBI_29728 GO:0062181 biolink:MolecularActivity 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity Catatlysis of the reaction: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]. RHEA:49192 go-plus.json http://purl.obolibrary.org/obo/GO_0062181 GO:0062180 biolink:MolecularActivity 25-hydroxycholecalciferol-23-hydroxylase activity Catalysis of the reaction: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]. RHEA:46616 go-plus.json http://purl.obolibrary.org/obo/GO_0062180 CHEBI:425902 biolink:ChemicalSubstance propiophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_425902 chebi_ph7_3 GO:0062183 biolink:MolecularActivity all-trans retinoic acid 18-hydroxylase activity Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:55856 go-plus.json http://purl.obolibrary.org/obo/GO_0062183 GO:0062182 biolink:MolecularActivity all-trans retinoic acid 4-hydrolase activity Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:51492 go-plus.json http://purl.obolibrary.org/obo/GO_0062182 GO:0062185 biolink:MolecularActivity secalciferol 1-monooxygenase activity Catalysis of the reaction:2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin]. RHEA:49064 go-plus.json http://purl.obolibrary.org/obo/GO_0062185 GO:0062184 biolink:MolecularActivity testosterone 16-beta-hydroxylase activity Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. RHEA:46304 go-plus.json http://purl.obolibrary.org/obo/GO_0062184 GO:0062187 biolink:MolecularActivity anandamide 8,9 epoxidase activity Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]. RHEA:53140 go-plus.json http://purl.obolibrary.org/obo/GO_0062187 CHEBI:30719 biolink:ChemicalSubstance citraconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_30719 chebi_ph7_3 GO:0062186 biolink:MolecularActivity anandamide epoxidase activity Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide. go-plus.json arachidonoylethanolamide epoxidase activity http://purl.obolibrary.org/obo/GO_0062186 GO:1904389 biolink:BiologicalProcess rod bipolar cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell. go-plus.json http://purl.obolibrary.org/obo/GO_1904389 GO:0062189 biolink:MolecularActivity anandamide 14,15 epoxidase activity Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]. RHEA:53148 go-plus.json http://purl.obolibrary.org/obo/GO_0062189 GO:1904388 biolink:BiologicalProcess negative regulation of ncRNA transcription associated with protein coding gene TSS/TES Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES. go-plus.json inhibition of ncRNA transcription associated with protein coding gene TSS/TES|downregulation of pasRNA transcription|down regulation of pasRNA transcription|down regulation of ncRNA transcription associated with protein coding gene TSS/TES|inhibition of pasRNA transcription|downregulation of ncRNA transcription associated with protein coding gene TSS/TES|down-regulation of ncRNA transcription associated with protein coding gene TSS/TES|down-regulation of pasRNA transcription|negative regulation of pasRNA transcription http://purl.obolibrary.org/obo/GO_1904388 GO:0062188 biolink:MolecularActivity anandamide 11,12 epoxidase activity Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]. RHEA:53144 go-plus.json http://purl.obolibrary.org/obo/GO_0062188 GO:1904398 biolink:BiologicalProcess positive regulation of neuromuscular junction development Any process that activates or increases the frequency, rate or extent of neuromuscular junction development. go-plus.json activation of neuromuscular junction organization|positive regulation of neuromuscular junction organization|activation of neuromuscular junction stability|up-regulation of neuromuscular junction development|activation of neuromuscular junction development|up regulation of NMJ stability|positive regulation of neuromuscular junction stability|up-regulation of neuromuscular junction organization|up regulation of neuromuscular junction stability|positive regulation of NMJ stability|activation of NMJ stability|upregulation of neuromuscular junction organization|up regulation of neuromuscular junction development|upregulation of neuromuscular junction stability|up-regulation of NMJ stability|up regulation of neuromuscular junction organization|upregulation of neuromuscular junction development|up-regulation of neuromuscular junction stability|upregulation of NMJ stability http://purl.obolibrary.org/obo/GO_1904398 GO:1904397 biolink:BiologicalProcess negative regulation of neuromuscular junction development Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development. go-plus.json down regulation of NMJ stability|negative regulation of neuromuscular junction organization|down-regulation of neuromuscular junction organization|down-regulation of neuromuscular junction stability|negative regulation of neuromuscular junction stability|downregulation of NMJ stability|inhibition of neuromuscular junction organization|downregulation of neuromuscular junction stability|down-regulation of neuromuscular junction development|down-regulation of NMJ stability|negative regulation of NMJ stability|down regulation of neuromuscular junction stability|downregulation of neuromuscular junction development|down regulation of neuromuscular junction organization|inhibition of neuromuscular junction stability|inhibition of NMJ stability|down regulation of neuromuscular junction development|downregulation of neuromuscular junction organization|inhibition of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1904397 GO:1904396 biolink:BiologicalProcess regulation of neuromuscular junction development Any process that modulates the frequency, rate or extent of neuromuscular junction development. go-plus.json regulation of NMJ stability|regulation of neuromuscular junction stability|regulation of neuromuscular junction organization http://purl.obolibrary.org/obo/GO_1904396 GO:1904395 biolink:BiologicalProcess positive regulation of skeletal muscle acetylcholine-gated channel clustering Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. go-plus.json up regulation of skeletal muscle acetylcholine-gated channel clustering|up regulation of skeletal muscle AChR clustering|upregulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle AChR clustering|positive regulation of skeletal muscle AChR clustering|upregulation of skeletal muscle acetylcholine-gated channel clustering|up regulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle nicotinic acetylcholine receptor clustering|positive regulation of skeletal muscle nicotinic acetylcholine receptor clustering|up-regulation of skeletal muscle AChR clustering|activation of skeletal muscle acetylcholine-gated channel clustering|up-regulation of skeletal muscle acetylcholine-gated channel clustering|upregulation of skeletal muscle AChR clustering|up-regulation of skeletal muscle nicotinic acetylcholine receptor clustering http://purl.obolibrary.org/obo/GO_1904395 GO:1904394 biolink:BiologicalProcess negative regulation of skeletal muscle acetylcholine-gated channel clustering Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. go-plus.json downregulation of skeletal muscle acetylcholine-gated channel clustering|down regulation of skeletal muscle nicotinic acetylcholine receptor clustering|down regulation of skeletal muscle acetylcholine-gated channel clustering|down-regulation of skeletal muscle AChR clustering|inhibition of skeletal muscle acetylcholine-gated channel clustering|negative regulation of skeletal muscle AChR clustering|downregulation of skeletal muscle nicotinic acetylcholine receptor clustering|inhibition of skeletal muscle AChR clustering|down-regulation of skeletal muscle nicotinic acetylcholine receptor clustering|negative regulation of skeletal muscle nicotinic acetylcholine receptor clustering|inhibition of skeletal muscle nicotinic acetylcholine receptor clustering|down-regulation of skeletal muscle acetylcholine-gated channel clustering|down regulation of skeletal muscle AChR clustering|downregulation of skeletal muscle AChR clustering http://purl.obolibrary.org/obo/GO_1904394 GO:1904393 biolink:BiologicalProcess regulation of skeletal muscle acetylcholine-gated channel clustering Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. go-plus.json regulation of skeletal muscle nicotinic acetylcholine receptor clustering|regulation of skeletal muscle AChR clustering http://purl.obolibrary.org/obo/GO_1904393 GO:1904392 biolink:BiologicalProcess cellular response to ciliary neurotrophic factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904392 GO:1904391 biolink:BiologicalProcess response to ciliary neurotrophic factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904391 GO:1904390 biolink:BiologicalProcess cone retinal bipolar cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell. go-plus.json cone bipolar cell differentiation|retinal cone bipolar cell differentiation http://purl.obolibrary.org/obo/GO_1904390 CHEBI:8588 biolink:ChemicalSubstance protodioscin go-plus.json http://purl.obolibrary.org/obo/CHEBI_8588 chebi_ph7_3 GO:0052722 biolink:MolecularActivity fatty acid in-chain hydroxylase activity Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O. RHEA:45084|MetaCyc:RXN-12186 go-plus.json http://purl.obolibrary.org/obo/GO_0052722 GO:0003799 biolink:MolecularActivity obsolete antifungal peptide activity OBSOLETE. Inhibits the growth of, or directly kills, fungal cells. go-plus.json antifungal peptide activity http://purl.obolibrary.org/obo/GO_0003799 GO:0003798 biolink:MolecularActivity obsolete male-specific antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells, but which is only expressed in males. go-plus.json male-specific antibacterial peptide activity http://purl.obolibrary.org/obo/GO_0003798 GO:0052721 biolink:BiologicalProcess regulation of apurinic/apyrimidinic endodeoxyribonuclease activity Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. go-plus.json regulation of apyrimidinic endodeoxyribonuclease activity|regulation of apurinic endodeoxyribonuclease activity|regulation of abasic endodeoxyribonuclease activity|regulation of AP endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0052721 GO:0052720 biolink:MolecularActivity class II DNA-(apurinic or apyrimidinic site) endonuclease activity Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. go-plus.json class II DNA-(apurinic or apyrimidinic site) lyase activity http://purl.obolibrary.org/obo/GO_0052720 GO:0052726 biolink:MolecularActivity inositol-1,3,4-trisphosphate 5-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+). RHEA:13253|Reactome:R-HSA-994140|Reactome:R-HSA-1855172|KEGG_REACTION:R03428|MetaCyc:2.7.1.139-RXN|EC:2.7.1.159 go-plus.json ins(1,3,4)P(3) 5-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|inositol-trisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity|Ins(1,3,4)P3 5-kinase activity|IP3 5-kinase activity|inositol 1,3,4-trisphosphate 5-kinase activity http://purl.obolibrary.org/obo/GO_0052726 GO:0003795 biolink:MolecularActivity obsolete antimicrobial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, microbial cells. go-plus.json antimicrobial peptide activity http://purl.obolibrary.org/obo/GO_0003795 GO:0052725 biolink:MolecularActivity inositol-1,3,4-trisphosphate 6-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+). Reactome:R-HSA-1855197|Reactome:R-HSA-2267372|RHEA:20940|MetaCyc:2.7.1.133-RXN|EC:2.7.1.159 go-plus.json 1D-myo-inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 6-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity|Ins(1,3,4)P3 6-kinase activity|IP3 6-kinase activity|inositol 1,3,4-trisphosphate 6-kinase activity|ins(1,3,4)P(3) 6-kinase activity http://purl.obolibrary.org/obo/GO_0052725 GO:0003794 biolink:MolecularActivity obsolete acute-phase response protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json acute-phase response protein activity http://purl.obolibrary.org/obo/GO_0003794 GO:0052724 biolink:MolecularActivity inositol hexakisphosphate 3-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate. MetaCyc:RXN-10971|EC:2.7.4.21 go-plus.json http://purl.obolibrary.org/obo/GO_0052724 GO:0003797 biolink:MolecularActivity obsolete antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells. go-plus.json antibacterial peptide activity http://purl.obolibrary.org/obo/GO_0003797 GO:0052723 biolink:MolecularActivity inositol hexakisphosphate 1-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate. MetaCyc:RXN-10972|RHEA:37459|KEGG_REACTION:R05799|EC:2.7.4.21 go-plus.json http://purl.obolibrary.org/obo/GO_0052723 GO:0003796 biolink:MolecularActivity lysozyme activity Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan. MetaCyc:3.2.1.17-RXN|Reactome:R-HSA-8862320|EC:3.2.1.17 go-plus.json mucopeptide N-acetylmuramoylhydrolase activity|N,O-diacetylmuramidase activity|peptidoglycan N-acetylmuramoylhydrolase activity|lysozyme g|1,4-N-acetylmuramidase activity|PR1-lysozyme|globulin G|L-7001|mucopeptide glucohydrolase activity|globulin G1|muramidase activity http://purl.obolibrary.org/obo/GO_0003796 GO:0003791 biolink:MolecularActivity obsolete membrane associated actin binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json membrane associated actin binding http://purl.obolibrary.org/obo/GO_0003791 CHEBI:64023 biolink:ChemicalSubstance 1-palmitoylglycerol 3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64023 GO:0052729 biolink:MolecularActivity dimethylglycine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine. MetaCyc:R482-RXN|KEGG_REACTION:R07244|RHEA:10072|EC:2.1.1.157|EC:2.1.1.162|EC:2.1.1.161|MetaCyc:RXN-9680 go-plus.json ApDMT|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052729 GO:0003790 biolink:MolecularActivity obsolete actin modulating activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json actin modulating activity http://purl.obolibrary.org/obo/GO_0003790 GO:0003793 biolink:MolecularActivity obsolete defense/immunity protein activity OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease. go-plus.json defence/immunity protein activity|defense/immunity protein activity http://purl.obolibrary.org/obo/GO_0003793 GO:0052728 biolink:MolecularActivity capsorubin synthase activity Catalysis of the reaction: violaxanthin = capsorubin. MetaCyc:RXN-7946|EC:5.3.99.8|RHEA:21752 go-plus.json CCS|capsanthin-capsorubin synthase activity|ketoxanthophyll synthase activity|violaxanthin-capsorubin isomerase (ketone-forming) activity http://purl.obolibrary.org/obo/GO_0052728 NCBITaxon:210 biolink:OrganismalEntity Helicobacter pylori go-plus.json Campylobacter pyloridis|Campylobacter pylori subsp. pylori|Helicobacter nemestrinae|Campylobacter pylori http://purl.obolibrary.org/obo/NCBITaxon_210 GO:0003792 biolink:MolecularActivity obsolete regulation of actin thin filament length activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json regulation of actin thin filament length activity http://purl.obolibrary.org/obo/GO_0003792 GO:0052727 biolink:MolecularActivity capsanthin synthase activity Catalysis of the reaction: antheraxanthin = capsanthin. RHEA:17373|MetaCyc:RXN-7947|EC:5.3.99.8 go-plus.json CCS|capsanthin-capsorubin synthase activity|ketoxanthophyll synthase activity http://purl.obolibrary.org/obo/GO_0052727 CHEBI:64024 biolink:ChemicalSubstance beta-D-GlcpA-(1->3)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_64024 CHEBI:78664 biolink:ChemicalSubstance (5Z,11Z,14Z,17Z)-icosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78664 chebi_ph7_3 CHEBI:39056 biolink:ChemicalSubstance nitrilotriacetate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_39056 CHEBI:39055 biolink:ChemicalSubstance 2,2'-[(carboxymethyl)imino]diacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_39055 CHEBI:78663 biolink:ChemicalSubstance (5Z,11Z,14Z)-icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78663 chebi_ph7_3 CHEBI:39054 biolink:ChemicalSubstance NTA go-plus.json http://purl.obolibrary.org/obo/CHEBI_39054 CHEBI:78662 biolink:ChemicalSubstance 2,3-epoxysqualene go-plus.json http://purl.obolibrary.org/obo/CHEBI_78662 chebi_ph7_3 CHEBI:39053 biolink:ChemicalSubstance nitrilotriacetate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_39053 CHEBI:78666 biolink:ChemicalSubstance 5beta-pregnan-20alpha-ol-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_78666 chebi_ph7_3 CHEBI:39057 biolink:ChemicalSubstance 2,2',2''-ammoniotriacetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_39057 chebi_ph7_3 GO:0052733 biolink:MolecularActivity quinate 3-dehydrogenase (NADP+) activity Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+. KEGG_REACTION:R06846|RHEA:18425|EC:1.1.1.282 go-plus.json quinate:NADP(+) 3-oxidoreductase activity|quinic dehydrogenase activity|quinate:NADP 3-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052733 GO:0052732 biolink:MolecularActivity phosphoethanolamine phosphatase activity Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate. EC:3.1.3.75|KEGG_REACTION:R06870|RHEA:16089|Reactome:R-HSA-1483096|MetaCyc:RXN-7948 go-plus.json phosphoethanolamine phosphohydrolase activity|3X11A|PHOSPHO1 http://purl.obolibrary.org/obo/GO_0052732 GO:0052731 biolink:MolecularActivity phosphocholine phosphatase activity Catalysis of the reaction: choline phosphate + H2O = choline + phosphate. EC:3.1.3.75|Reactome:R-HSA-1483159|KEGG_REACTION:R06871|RHEA:10492|MetaCyc:RXN-5647 go-plus.json phosphoethanolamine phosphohydrolase activity|3X11A|PHOSPHO1 http://purl.obolibrary.org/obo/GO_0052731 GO:0052730 biolink:MolecularActivity sarcosine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine. MetaCyc:RXN-7042|MetaCyc:R481-RXN|RHEA:15453|KEGG_REACTION:R07243|EC:2.1.1.157|EC:2.1.1.156|EC:2.1.1.162|MetaCyc:RXN-9679 go-plus.json SDMT|S-adenosyl-L-methionine:N,N-sarcosine N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052730 GO:0052737 biolink:MolecularActivity pyruvate dehydrogenase (quinone) activity Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2. RHEA:27405|KEGG_REACTION:R03145|EC:1.2.5.1|MetaCyc:RXN-11496 go-plus.json pyruvate:ubiquinone-8-oxidoreductase activity|pyruvate:ubiquinone oxidoreductase activity|pyruvic dehydrogenase activity|pyruvate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052737 GO:0052736 biolink:MolecularActivity beta-glucanase activity Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds. go-plus.json beta-D-glucanase activity http://purl.obolibrary.org/obo/GO_0052736 GO:0052735 biolink:MolecularActivity tRNA (cytosine-3-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine. go-plus.json S-adenosyl-L-methionine:tRNA (cytosine-3-)-methyltransferase activity|tRNA (cytosine 3)-methyltransferase activity|tRNA cytosine 3-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-3-methyltransferase activity|tRNA cytosine-3-methyltransferase activity|transfer ribonucleate cytosine 3-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052735 GO:0052734 biolink:MolecularActivity shikimate 3-dehydrogenase (NAD+) activity Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+. KEGG_REACTION:R06847|RHEA:17741|EC:1.1.1.282 go-plus.json DHS reductase activity|shikimate:NAD(P)(+) 3-oxidoreductase activity|3-dehydroshikimate reductase activity|shikimate oxidoreductase activity|shikimate:NAD(P)(+) oxidoreductase activity|3-dehydroshikimic reductase activity|dehydroshikimic reductase activity http://purl.obolibrary.org/obo/GO_0052734 CHEBI:64033 biolink:ChemicalSubstance EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_64033 GO:0052739 biolink:MolecularActivity phosphatidylserine 1-acylhydrolase activity Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid. EC:3.1.1.32|KEGG_REACTION:R04034|Reactome:R-HSA-8869425 go-plus.json phosphatidylserine-specific phospholipase A1 activity http://purl.obolibrary.org/obo/GO_0052739 CHEBI:64032 biolink:ChemicalSubstance linoleoyl ethanolamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64032 chebi_ph7_3 CHEBI:64031 biolink:ChemicalSubstance (3E)-2-oxohex-3-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64031 GO:0052738 biolink:MolecularActivity oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound. EC:1.2.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0052738 CHEBI:64038 biolink:ChemicalSubstance (3Z)-2-oxohex-3-enedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64038 CHEBI:64037 biolink:ChemicalSubstance (2E,4Z)-2-hydroxymuconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64037 CHEBI:64039 biolink:ChemicalSubstance (2S)-pristanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_64039 CHEBI:78670 biolink:ChemicalSubstance (8Z,11Z)-icosadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78670 chebi_ph7_3 CHEBI:78675 biolink:ChemicalSubstance fundamental metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_78675 CHEBI:78679 biolink:ChemicalSubstance D-ribose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78679 CHEBI:15076 biolink:ChemicalSubstance selenide go-plus.json http://purl.obolibrary.org/obo/CHEBI_15076 CHEBI:15075 biolink:ChemicalSubstance selenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15075 chebi_ph7_3 GO:0003777 biolink:MolecularActivity microtubule motor activity A motor activity that generates movement along a microtubule, driven by ATP hydrolysis. Reactome:R-HSA-9610627|Reactome:R-HSA-177479|Reactome:R-HSA-265160 go-plus.json dynein ATPase activity|dynein|kinesin motor activity|ATP-dependent microtubule motor activity|kinesin|axonemal motor activity|kinetochore motor activity http://purl.obolibrary.org/obo/GO_0003777 PO:0002003 biolink:OntologyClass xylem vessel member A tracheary element (PO:0000290) that is part of a xylem vessel (PO:0025417) and has as parts perforation plates. go-plus.json miembro de vaso (Spanish, exact)|vessel element (exact)|vessel segment (exact)|木質部道管状要素 (Japanese, exact)|vessel member (exact) http://purl.obolibrary.org/obo/PO_0002003 GO:0052744 biolink:MolecularActivity phosphatidylinositol monophosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052744 GO:0003776 biolink:MolecularActivity obsolete muscle motor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json muscle motor activity http://purl.obolibrary.org/obo/GO_0003776 GO:0052743 biolink:MolecularActivity inositol tetrakisphosphate phosphatase activity Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052743 PO:0002002 biolink:OntologyClass embryo basal cell A native plant cell (PO:0025606) that is the lower-most cell formed after the first division of the plant zygote (PO:0000423) and is part of a plant embryo (PO:0009009). go-plus.json embryonic basal cell (exact)|célula basal (Spanish, exact)|胚基底細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0002002 GO:0052742 biolink:MolecularActivity phosphatidylinositol kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052742 GO:0003779 biolink:MolecularActivity actin binding Binding to monomeric or multimeric forms of actin, including actin filaments. go-plus.json membrane associated actin binding http://purl.obolibrary.org/obo/GO_0003779 GO:0052741 biolink:MolecularActivity (R)-limonene 6-monooxygenase activity Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+. EC:1.14.14.53|KEGG_REACTION:R06119|RHEA:18957|MetaCyc:1.14.13.84-RXN go-plus.json (+)-limonene-6-hydroxylase activity|(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity|(+)-limonene 6-monooxygenase activity http://purl.obolibrary.org/obo/GO_0052741 GO:0003778 biolink:MolecularActivity obsolete dynactin motor OBSOLETE. (Was not defined before being made obsolete). go-plus.json dynactin motor http://purl.obolibrary.org/obo/GO_0003778 GO:0052748 biolink:MolecularActivity baicalin beta-D-glucuronidase activity Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate. EC:3.2.1.167|RHEA:28130|MetaCyc:RXN-11760|KEGG_REACTION:R09533 go-plus.json 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase activity|baicalinase activity http://purl.obolibrary.org/obo/GO_0052748 GO:0003773 biolink:MolecularActivity obsolete heat shock protein activity OBSOLETE. Any of a group of specific proteins that are synthesized by both prokaryotic and eukaryotic cells after they have been exposed to a temperature that is higher than normal. Other stresses, e.g. free radical damage, have a similar effect. Many members of the hsp family are not induced but are present in all cells. They are characterized by their role as molecular chaperones. go-plus.json heat shock protein activity http://purl.obolibrary.org/obo/GO_0003773 GO:0003772 biolink:MolecularActivity obsolete co-chaperonin activity OBSOLETE. Co-chaperonins are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperonins by themselves do not possess chaperone activity. go-plus.json co-chaperonin activity http://purl.obolibrary.org/obo/GO_0003772 GO:0052747 biolink:MolecularActivity sinapyl alcohol dehydrogenase activity Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+. MetaCyc:RXN-1125|EC:1.1.1.195|KEGG_REACTION:R03918|RHEA:45704 go-plus.json sinapyl-alcohol:NADP+ oxidoreductase activity|sinapyl-alcohol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052747 GO:0003775 biolink:MolecularActivity obsolete axonemal motor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json axonemal motor activity http://purl.obolibrary.org/obo/GO_0003775 GO:0052746 biolink:BiologicalProcess inositol phosphorylation The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms. go-plus.json inositol and derivative phosphorylation|myo-inositol and derivative phosphorylation|myo-inositol phosphorylation http://purl.obolibrary.org/obo/GO_0052746 GO:0003774 biolink:MolecularActivity cytoskeletal motor activity Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force). Reactome:R-HSA-1861595 go-plus.json motor activity http://purl.obolibrary.org/obo/GO_0003774 goslim_candida|goslim_pir|goslim_plant|goslim_aspergillus GO:0052745 biolink:MolecularActivity inositol phosphate phosphatase activity Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0052745 GO:0003771 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003771 CHEBI:40036 biolink:ChemicalSubstance amitrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_40036 chebi_ph7_3 GO:0052749 biolink:MolecularActivity glucose-6-phosphate dehydrogenase (coenzyme F420) activity Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420. KEGG_REACTION:R09550|RHEA:27294|EC:1.1.98.2|MetaCyc:RXN-11283 go-plus.json coenzyme F420-dependent glucose-6-phosphate dehydrogenase activity|D-glucose-6-phosphate:F420 1-oxidoreductase activity|F420-dependent glucose-6-phosphate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0052749 GO:0003770 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003770 CHEBI:64049 biolink:ChemicalSubstance food acidity regulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_64049 CHEBI:88015 biolink:ChemicalSubstance archaeal dolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_88015 chebi_ph7_3 CHEBI:64047 biolink:ChemicalSubstance food additive go-plus.json http://purl.obolibrary.org/obo/CHEBI_64047 CHEBI:78682 biolink:ChemicalSubstance D-fructose 1,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78682 CHEBI:78680 biolink:ChemicalSubstance (9Z,12Z)-tetradecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78680 chebi_ph7_3 CHEBI:78686 biolink:ChemicalSubstance Delta(4)-dafachronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78686 CHEBI:78684 biolink:ChemicalSubstance (9Z,12Z)-pentadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78684 chebi_ph7_3 GO:0052740 biolink:MolecularActivity 1-acyl-2-lysophosphatidylserine acylhydrolase activity Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate. EC:3.1.1.32 go-plus.json phosphatidylserine-specific phospholipase A1 activity http://purl.obolibrary.org/obo/GO_0052740 CHEBI:78688 biolink:ChemicalSubstance 2,4-diacetylphloroglucinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78688 CHEBI:78687 biolink:ChemicalSubstance D-fructofuranose 2,6-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78687 GO:0052755 biolink:MolecularActivity reduced coenzyme F420:quinone oxidoreductase activity Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone. go-plus.json F420H2:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity|F420H2-dependent quinone oxidoreductase activity|F420H2:quinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052755 GO:0003788 biolink:MolecularActivity obsolete actin monomer sequestering activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json actin monomer sequestering activity http://purl.obolibrary.org/obo/GO_0003788 GO:0052754 biolink:MolecularActivity GTP:coenzyme F420 guanyltransferase activity Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate. go-plus.json GTP:coenzyme F420 guanylyltransferase activity|coenzyme F390-G synthetase activity http://purl.obolibrary.org/obo/GO_0052754 GO:0003787 biolink:MolecularActivity obsolete actin depolymerizing activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json actin depolymerizing activity http://purl.obolibrary.org/obo/GO_0003787 GO:0052753 biolink:MolecularActivity propan-2-ol:coenzyme F420 oxidoreductase activity Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420. go-plus.json F420-dependent secondary alcohol dehydrogenase activity|F420-dependent propan-2-ol dehydrogenase activity|isopropanol:coenzyme F420 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052753 GO:0052752 biolink:MolecularActivity reduced coenzyme F420:heterodisulfide oxidoreductase activity Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH. go-plus.json coenzyme F420-dependent heterodisulfide oxidoreductase activity|F420H2:heterodisulfide oxidoreductase activity|F420-dependent heterodisulfide oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052752 GO:0003789 biolink:MolecularActivity obsolete actin filament severing activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json actin filament severing activity http://purl.obolibrary.org/obo/GO_0003789 GO:0052759 biolink:MolecularActivity coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction. EC:1.3.99.-|UM-BBD_reactionID:r1066 go-plus.json coenzyme F420-dependent 2,4,6-trinitrophenol-hydride-Meisenheimer-complex hydride transferase activity http://purl.obolibrary.org/obo/GO_0052759 GO:0003784 biolink:MolecularActivity obsolete barbed-end actin capping/severing activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json barbed-end actin capping/severing activity http://purl.obolibrary.org/obo/GO_0003784 GO:0052758 biolink:MolecularActivity coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction. EC:1.3.99.-|UM-BBD_reactionID:r1065 go-plus.json TNP reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity http://purl.obolibrary.org/obo/GO_0052758 GO:0003783 biolink:MolecularActivity obsolete barbed-end actin capping activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json barbed-end actin capping activity http://purl.obolibrary.org/obo/GO_0003783 GO:0003786 biolink:MolecularActivity actin lateral binding Binding to an actin filament along its length. go-plus.json http://purl.obolibrary.org/obo/GO_0003786 GO:0052757 biolink:MolecularActivity chondroitin hydrolase activity Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-]. go-plus.json chondroitin endo-beta-galactosaminidase activity http://purl.obolibrary.org/obo/GO_0052757 GO:0003785 biolink:MolecularActivity actin monomer binding Binding to monomeric actin, also known as G-actin. go-plus.json G actin binding http://purl.obolibrary.org/obo/GO_0003785 GO:0052756 biolink:MolecularActivity chitobiose phosphorylase activity Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units. go-plus.json http://purl.obolibrary.org/obo/GO_0052756 GO:0003780 biolink:MolecularActivity obsolete actin cross-linking activity OBSOLETE. Interacting selectively with two actin filaments to anchor them together. go-plus.json actin cross-linking activity http://purl.obolibrary.org/obo/GO_0003780 GO:0003782 biolink:MolecularActivity obsolete F-actin capping activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json F-actin capping activity http://purl.obolibrary.org/obo/GO_0003782 CHEBI:88003 biolink:ChemicalSubstance fructose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_88003 CHEBI:64054 biolink:ChemicalSubstance delta-opioid receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_64054 GO:0003781 biolink:MolecularActivity obsolete actin bundling activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json actin bundling activity http://purl.obolibrary.org/obo/GO_0003781 CHEBI:88005 biolink:ChemicalSubstance 3-phosphoglycerate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88005 CHEBI:88004 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_88004 CHEBI:88007 biolink:ChemicalSubstance 3-oxooleoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88007 CHEBI:88008 biolink:ChemicalSubstance (7Z)-hexadecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_88008 CHEBI:78691 biolink:ChemicalSubstance EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_78691 CHEBI:78690 biolink:ChemicalSubstance (9Z,12Z)-heptadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78690 chebi_ph7_3 CHEBI:78697 biolink:ChemicalSubstance D-fructose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78697 GO:0052751 biolink:MolecularActivity GDP-mannose hydrolase activity Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate. go-plus.json GDP-mannose pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0052751 GO:0052750 biolink:MolecularActivity reactive-black-5:hydrogen-peroxide oxidoreductase activity Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O. KEGG_REACTION:R07612|RHEA:22396|EC:1.11.1.16|MetaCyc:RXN-8666 go-plus.json versatile peroxidase activity http://purl.obolibrary.org/obo/GO_0052750 CHEBI:78699 biolink:ChemicalSubstance Delta(7)-dafachronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_78699 PO:0002000 biolink:OntologyClass stomatal complex A portion of shoot system epidermis (PO:0006035) that has as parts two guard cells (PO:0000293) and a stomatal pore (PO:0008032). May also contain subsidiary cells (PO:0000284). go-plus.json stoma (broad)|stomate (exact)|complejo estomático (Spanish, exact)|気孔装置 (Japanese, exact)|stomata (broad)|stomatal apparatus (exact) http://purl.obolibrary.org/obo/PO_0002000 CHEBI:78698 biolink:ChemicalSubstance dafachronic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_78698 GO:0003755 biolink:MolecularActivity peptidyl-prolyl cis-trans isomerase activity Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). Reactome:R-HSA-2022073|EC:5.2.1.8|RHEA:16237|Reactome:R-HSA-9626816|MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN go-plus.json peptidylprolyl cis-trans isomerase activity|peptidyl-prolyl isomerase B reaction|parvulin|juglone-sensitive cis-trans proline isomerase activity|PPIase activity|cis-trans proline isomerase activity|immunophilin|rotamase activity|cyclophilin activity|peptide bond isomerase activity|FK506-sensitive peptidyl-prolyl cis-trans isomerase|cyclophilin-type peptidyl-prolyl cis-trans isomerase activity|peptidylproline cis-trans-isomerase activity|peptidylprolyl isomerase activity|juglone-sensitive peptidyl-prolyl cis-trans isomerase activity http://purl.obolibrary.org/obo/GO_0003755 GO:0052766 biolink:MolecularActivity mannoside alpha-1,4-mannosidase activity Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. go-plus.json alpha-1,4-exomannosidase activity|mannoside alpha-1,4-exomannosidase activity|mannoside exo-alpha-1,4-mannosidase activity|alpha-1,4-mannosidase activity http://purl.obolibrary.org/obo/GO_0052766 GO:0052765 biolink:MolecularActivity reduced coenzyme F420 oxidase activity Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O. go-plus.json F420H2:oxygen oxidoreductase activity|coenzyme F420H2 oxidase activity|F420H2 oxidase activity http://purl.obolibrary.org/obo/GO_0052765 GO:0003754 biolink:MolecularActivity obsolete chaperone activity OBSOLETE. Assists in the correct non-covalent assembly of polypeptide-containing structures in vivo, but is not a component of these assembled structures when they are performing their normal biological function. go-plus.json chaperone activity http://purl.obolibrary.org/obo/GO_0003754 GO:0052764 biolink:MolecularActivity exo-oligoalginate lyase activity Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. EC:4.2.2.26 go-plus.json http://purl.obolibrary.org/obo/GO_0052764 GO:0003757 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003757 GO:0003756 biolink:MolecularActivity protein disulfide isomerase activity Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins. Reactome:R-HSA-8950456|Reactome:R-HSA-8950113|MetaCyc:5.3.4.1-RXN|Reactome:R-HSA-8950183|EC:5.3.4.1 go-plus.json protein thiol-disulfide exchange|protein disulfide-isomerase reaction|disulphide bond formation|protein disulphide isomerase activity|protein cysteine-thiol oxidation|protein thiol-disulphide exchange|protein disulfide-isomerase|disulphide bond biosynthesis|S-S rearrangase activity http://purl.obolibrary.org/obo/GO_0003756 GO:0052763 biolink:MolecularActivity ulvan lyase activity Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end. go-plus.json http://purl.obolibrary.org/obo/GO_0052763 GO:0003751 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003751 GO:0052769 biolink:MolecularActivity beta-6-sulfate-N-acetylglucosaminidase activity Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative. go-plus.json beta-6-SO3-N-acetylglucosaminidase activity|sulfomucin beta-6-sulfate-N-acetylglucosaminidase activity|exosulfoglycosidase activity|sulfoglycosidase activity http://purl.obolibrary.org/obo/GO_0052769 GO:0003750 biolink:MolecularActivity obsolete cell cycle regulator OBSOLETE. (Was not defined before being made obsolete). go-plus.json cell cycle regulator http://purl.obolibrary.org/obo/GO_0003750 GO:0052768 biolink:MolecularActivity mannosyl-oligosaccharide 1,3-alpha-mannosidase activity Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. EC:3.1.1.- go-plus.json 1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,3-alpha-mannosidase activity|alpha-1,3-mannosidase activity http://purl.obolibrary.org/obo/GO_0052768 GO:0003753 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003753 GO:0052767 biolink:MolecularActivity mannosyl-oligosaccharide 1,6-alpha-mannosidase activity Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. EC:3.1.1.- go-plus.json 1,6-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,6-mannosidase activity|1,6-alpha-mannosidase activity http://purl.obolibrary.org/obo/GO_0052767 GO:0003752 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003752 CHEBI:29699 biolink:ChemicalSubstance tunicamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_29699 chebi_ph7_3 CHEBI:15045 biolink:ChemicalSubstance riboflavin cyclic 4',5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15045 CHEBI:30684 biolink:ChemicalSubstance alpha-D-glucosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30684 chebi_ph7_3 GO:0052762 biolink:MolecularActivity gellan lyase activity Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha). MetaCyc:RXN-12269|EC:4.2.2.25 go-plus.json http://purl.obolibrary.org/obo/GO_0052762 GO:0003759 biolink:MolecularActivity obsolete glycoprotein-specific chaperone activity OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins. go-plus.json glycoprotein-specific chaperone activity http://purl.obolibrary.org/obo/GO_0003759 CHEBI:39015 biolink:ChemicalSubstance apolipoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_39015 GO:0052761 biolink:MolecularActivity exo-1,4-beta-D-glucosaminidase activity Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units. KEGG_REACTION:R08715|MetaCyc:3.2.1.165-RXN|EC:3.2.1.165 go-plus.json chitosan exo-1,4-beta-D-glucosaminidase activity|exochitosanase activity|chitosan glucosaminohydrolase activity|exo-beta-D-glucosaminidase activity http://purl.obolibrary.org/obo/GO_0052761 CHEBI:15040 biolink:ChemicalSubstance retinyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15040 GO:0003758 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003758 GO:0052760 biolink:MolecularActivity coenzyme F420-dependent 2,4-dinitrophenol reductase activity Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction. EC:1.3.99.-|UM-BBD_reactionID:r1071 go-plus.json coenzyme F420-dependent 2,4-dinitrophenol hydride transferase activity|DNP reductase activity http://purl.obolibrary.org/obo/GO_0052760 GO:0052777 biolink:BiologicalProcess diacetylchitobiose catabolic process The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products. go-plus.json diacetylchitobiose catabolism http://purl.obolibrary.org/obo/GO_0052777 GO:0003766 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003766 GO:0052776 biolink:BiologicalProcess diacetylchitobiose catabolic process to glucosamine and acetate The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate. go-plus.json http://purl.obolibrary.org/obo/GO_0052776 GO:0003765 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003765 GO:0003768 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003768 GO:0052775 biolink:MolecularActivity endo-1,3-alpha-L-rhamnosidase activity Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain. go-plus.json endo-(1,3)-alpha-L-rhamnosidase activity|endorhamnosidase activity|endo-(1->3)-alpha-L-rhamnosidase activity http://purl.obolibrary.org/obo/GO_0052775 GO:0003767 biolink:MolecularActivity obsolete co-chaperone activity OBSOLETE. Co-chaperones are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperones by themselves do not possess chaperone activity. go-plus.json co-chaperone activity http://purl.obolibrary.org/obo/GO_0003767 GO:0052774 biolink:MolecularActivity glucosyl-N-acetylglucosamine glucosaminidase activity Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine. go-plus.json http://purl.obolibrary.org/obo/GO_0052774 GO:0003762 biolink:MolecularActivity obsolete histone-specific chaperone activity OBSOLETE. Assists in chromatin assembly by chaperoning histones on to replicating DNA, but is not a component of the assembled nucleosome when performing its normal biological function. go-plus.json nucleosome assembly chaperone|histone-specific chaperone activity http://purl.obolibrary.org/obo/GO_0003762 CHEBI:64074 biolink:ChemicalSubstance (S)-NADHX(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64074 chebi_ph7_3 GO:0003761 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003761 GO:0003764 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003764 GO:0052779 biolink:BiologicalProcess amino disaccharide metabolic process The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions. go-plus.json http://purl.obolibrary.org/obo/GO_0052779 CHEBI:88021 biolink:ChemicalSubstance archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88021 chebi_ph7_3 GO:0052778 biolink:BiologicalProcess diacetylchitobiose metabolic process The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose. go-plus.json diacetylchitobiose metabolism http://purl.obolibrary.org/obo/GO_0052778 GO:0003763 biolink:MolecularActivity obsolete chaperonin ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts. go-plus.json chaperonin ATPase activity|chaperonin http://purl.obolibrary.org/obo/GO_0003763 CHEBI:64077 biolink:ChemicalSubstance (R)-NADPHX(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64077 chebi_ph7_3 CHEBI:64076 biolink:ChemicalSubstance (S)-NADPHX(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64076 chebi_ph7_3 GO:0003760 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003760 CHEBI:64075 biolink:ChemicalSubstance (R)-NADHX(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64075 chebi_ph7_3 CHEBI:88026 biolink:ChemicalSubstance archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy- beta-D-glucuronsyl)-N-acetyl- alpha-D-glucosaminyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88026 chebi_ph7_3 CHEBI:40009 biolink:ChemicalSubstance D-cycloserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_40009 CHEBI:30697 biolink:ChemicalSubstance beta-D-glucosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_30697 chebi_ph7_3 CHEBI:39022 biolink:ChemicalSubstance inclusion compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_39022 CHEBI:15036 biolink:ChemicalSubstance retinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_15036 chebi_ph7_3 CHEBI:15035 biolink:ChemicalSubstance retinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_15035 chebi_ph7_3 GO:0052773 biolink:MolecularActivity diacetylchitobiose deacetylase activity Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc). MetaCyc:RXN-12543 go-plus.json N,N'-diacetylchitobiose deacetylase (nonreducing end) http://purl.obolibrary.org/obo/GO_0052773 CHEBI:39027 biolink:ChemicalSubstance very-low-density lipoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_39027 GO:0003769 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003769 GO:0052772 biolink:MolecularActivity brefeldin A esterase activity Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone. go-plus.json brefeldin A hydrolase activity|BFA esterase activity http://purl.obolibrary.org/obo/GO_0052772 CHEBI:39026 biolink:ChemicalSubstance low-density lipoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_39026 GO:0052771 biolink:MolecularActivity coenzyme F390-G hydrolase activity Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420. go-plus.json 8-hydroxyguanylylated-coenzyme F420 hydrolase activity http://purl.obolibrary.org/obo/GO_0052771 CHEBI:39025 biolink:ChemicalSubstance high-density lipoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_39025 CHEBI:15031 biolink:ChemicalSubstance dihydroriboflavins go-plus.json http://purl.obolibrary.org/obo/CHEBI_15031 GO:0052770 biolink:MolecularActivity coenzyme F390-A hydrolase activity Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420. go-plus.json 8-hydroxyadenylylated-coenzyme F420 hydrolase activity http://purl.obolibrary.org/obo/GO_0052770 CHEBI:39024 biolink:ChemicalSubstance clathrate compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_39024 GO:0052788 biolink:MolecularActivity d-4,5 unsaturated beta-glucuronyl hydrolase activity Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue. go-plus.json unsaturated beta-glucuronyl hydrolase activity http://purl.obolibrary.org/obo/GO_0052788 GO:0003733 biolink:MolecularActivity obsolete ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json ribonucleoprotein http://purl.obolibrary.org/obo/GO_0003733 GO:0052787 biolink:BiologicalProcess alpha-linked polysaccharide catabolism to maltopentaose The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose. go-plus.json alpha-amylase-mediated polysaccharide catabolism, producing maltopentaose|maltopentaose-forming alpha-amylase activity http://purl.obolibrary.org/obo/GO_0052787 GO:0003732 biolink:MolecularActivity obsolete snRNA cap binding OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule. go-plus.json snRNA cap binding http://purl.obolibrary.org/obo/GO_0003732 GO:0003735 biolink:MolecularActivity structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome. go-plus.json ribosomal protein|ribosomal RNA http://purl.obolibrary.org/obo/GO_0003735 goslim_chembl|goslim_yeast|goslim_drosophila|goslim_metagenomics|goslim_generic GO:0052786 biolink:BiologicalProcess alpha-linked polysaccharide catabolism to maltotriose The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose. go-plus.json alpha-amylase-mediated polysaccharide catabolism, producing maltotriose|maltotriose-forming alpha-amylase activity http://purl.obolibrary.org/obo/GO_0052786 GO:0052785 biolink:BiologicalProcess cellulose catabolism by endo-processive cellulases The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments. go-plus.json endo-processive cellulase activity http://purl.obolibrary.org/obo/GO_0052785 GO:0003734 biolink:MolecularActivity obsolete small nuclear ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). go-plus.json small nuclear ribonucleoprotein|snRNP http://purl.obolibrary.org/obo/GO_0003734 CHEBI:88052 biolink:ChemicalSubstance prenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88052 chebi_ph7_3 CHEBI:64085 biolink:ChemicalSubstance (R)-NADPHX go-plus.json http://purl.obolibrary.org/obo/CHEBI_64085 CHEBI:29678 biolink:ChemicalSubstance sodium arsenite go-plus.json http://purl.obolibrary.org/obo/CHEBI_29678 CHEBI:64084 biolink:ChemicalSubstance (S)-NADPHX go-plus.json http://purl.obolibrary.org/obo/CHEBI_64084 GO:0003731 biolink:MolecularActivity obsolete mRNA cap binding OBSOLETE. Interacting selectively with the 7-methylguanosine cap at the 5' end of a nascent messenger RNA transcript. go-plus.json mRNA cap binding http://purl.obolibrary.org/obo/GO_0003731 CHEBI:88054 biolink:ChemicalSubstance [5-(ammoniomethyl)-3-furyl]methyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88054 chebi_ph7_3 GO:0052789 biolink:MolecularActivity mannan 1,3-beta-mannosidase activity Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose. go-plus.json exo-1,3-mannanase activity|beta-1,3-mannan 3-mannanohydrolase activity|1,3-beta-D-mannan mannanohydrolase activity|exo-1,3-beta-mannanase activity|exo-beta-1,3-mannase activity http://purl.obolibrary.org/obo/GO_0052789 CHEBI:88053 biolink:ChemicalSubstance phosphatidyl-myo-inositol 6-acylmannoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88053 chebi_ph7_3 GO:0003730 biolink:MolecularActivity mRNA 3'-UTR binding Binding to a 3' untranslated region of an mRNA molecule. go-plus.json mRNA 3' UTR binding http://purl.obolibrary.org/obo/GO_0003730 CHEBI:88056 biolink:ChemicalSubstance ganglioside GM1/1b(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88056 CHEBI:88055 biolink:ChemicalSubstance (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88055 chebi_ph7_3 CHEBI:88058 biolink:ChemicalSubstance ganglioside GT1(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88058 CHEBI:88057 biolink:ChemicalSubstance ganglioside GD1(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88057 GO:0062110 biolink:BiologicalProcess negative regulation of DNA recombinase disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0062110 CHEBI:88059 biolink:ChemicalSubstance ganglioside GQ1(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88059 GO:0062112 biolink:BiologicalProcess fatty acid primary amide biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid primary amide. go-plus.json fatty acid amide biosynthesis|FAPA biosynthesis|FAPA biosynthetic process http://purl.obolibrary.org/obo/GO_0062112 CHEBI:29673 biolink:ChemicalSubstance rifamycin SV go-plus.json http://purl.obolibrary.org/obo/CHEBI_29673 GO:0062111 biolink:BiologicalProcess zinc ion import into organelle The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle. go-plus.json http://purl.obolibrary.org/obo/GO_0062111 GO:0062113 biolink:CellularComponent early phagosome lumen The volume enclosed by the membrane of an eary phagosome. go-plus.json early phagocytic vesicle lumen http://purl.obolibrary.org/obo/GO_0062113 GO:0062116 biolink:CellularComponent phenyloplast A chloroplast-derived plastid in which the solid form of phenol is stored. go-plus.json http://purl.obolibrary.org/obo/GO_0062116 GO:0062119 biolink:CellularComponent LinE complex A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0062119 GO:0052780 biolink:BiologicalProcess chitobiose metabolic process The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine. go-plus.json http://purl.obolibrary.org/obo/GO_0052780 CHEBI:30661 biolink:ChemicalSubstance thyronine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30661 GO:0052784 biolink:BiologicalProcess reuteran biosynthetic process The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages. go-plus.json reuteransucrase-mediated reuteran biosynthesis http://purl.obolibrary.org/obo/GO_0052784 CHEBI:30660 biolink:ChemicalSubstance thyroxine go-plus.json http://purl.obolibrary.org/obo/CHEBI_30660 GO:0003737 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003737 GO:0052783 biolink:BiologicalProcess reuteran metabolic process The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0052783 GO:0003736 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003736 GO:0052782 biolink:BiologicalProcess amino disaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions. go-plus.json http://purl.obolibrary.org/obo/GO_0052782 GO:0003739 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003739 GO:0052781 biolink:BiologicalProcess chitobiose catabolic process The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine. go-plus.json http://purl.obolibrary.org/obo/GO_0052781 GO:0003738 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003738 GO:0003744 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003744 GO:0052799 biolink:BiologicalProcess coenzyme F420-dependent bicyclic nitroimidazole catabolic process The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates. go-plus.json coenzyme F420-dependent nitroimidazole breakdown|coenzyme F420-dependent nitroimidazole catabolism|coenzyme F420-dependent nitroimidazole reduction|coenzyme F420-dependent nitroreductase activity http://purl.obolibrary.org/obo/GO_0052799 GO:0052798 biolink:MolecularActivity beta-galactoside alpha-2,3-sialyltransferase activity Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor. go-plus.json trans-sialidase activity http://purl.obolibrary.org/obo/GO_0052798 GO:0003743 biolink:MolecularActivity translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. Reactome:R-HSA-72722|Reactome:R-HSA-72697|Reactome:R-HSA-72621 go-plus.json http://purl.obolibrary.org/obo/GO_0003743 GO:0003746 biolink:MolecularActivity translation elongation factor activity Functions in chain elongation during polypeptide synthesis at the ribosome. Reactome:R-HSA-192841|Reactome:R-HSA-192704 go-plus.json http://purl.obolibrary.org/obo/GO_0003746 GO:0052797 biolink:MolecularActivity 4-O-methyl-glucuronoyl methylesterase activity Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X]. go-plus.json glucuronoyl esterase activity http://purl.obolibrary.org/obo/GO_0052797 CHEBI:64090 biolink:ChemicalSubstance tert-butyl hydroperoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_64090 chebi_ph7_3 GO:0003745 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003745 GO:0052796 biolink:MolecularActivity exo-alpha-(2->8)-sialidase activity Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates. EC:3.2.1.18 go-plus.json exo-alpha-2,8-sialidase activity|exo-alpha-(2,8)-sialidase activity http://purl.obolibrary.org/obo/GO_0052796 GO:0003740 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003740 CHEBI:88041 biolink:ChemicalSubstance CDP-3,6-dideoxy-alpha-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88041 chebi_ph7_3 GO:1904309 biolink:BiologicalProcess response to cordycepin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus. go-plus.json response to 3'-deoxyadenosine http://purl.obolibrary.org/obo/GO_1904309 GO:0003742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003742 GO:1904308 biolink:BiologicalProcess cellular response to desipramine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904308 GO:0003741 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003741 CHEBI:88042 biolink:ChemicalSubstance UDP-beta-L-iduronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_88042 chebi_ph7_3 GO:1904307 biolink:BiologicalProcess response to desipramine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1904307 GO:1904306 biolink:BiologicalProcess positive regulation of gastro-intestinal system smooth muscle contraction Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. go-plus.json upregulation of gastro-intestinal system smooth muscle contraction|up-regulation of gastro-intestinal system smooth muscle contraction|activation of gastro-intestinal system smooth muscle contraction|up regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904306 GO:1904305 biolink:BiologicalProcess negative regulation of gastro-intestinal system smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. go-plus.json down regulation of gastro-intestinal system smooth muscle contraction|inhibition of gastro-intestinal system smooth muscle contraction|down-regulation of gastro-intestinal system smooth muscle contraction|downregulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904305 GO:1904304 biolink:BiologicalProcess regulation of gastro-intestinal system smooth muscle contraction Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. go-plus.json http://purl.obolibrary.org/obo/GO_1904304 NCBITaxon:287 biolink:OrganismalEntity Pseudomonas aeruginosa go-plus.json Bacterium aeruginosum|Pseudomonas pyocyanea|probable synonym or variety: "Pseudomonas polycolor" Clara 1930|Bacillus pyocyaneus|Pseudomonas polycolor|Bacterium pyocyaneum|Micrococcus pyocyaneus|Bacillus aeruginosus http://purl.obolibrary.org/obo/NCBITaxon_287 GO:1904303 biolink:BiologicalProcess positive regulation of maternal process involved in parturition Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition. go-plus.json up regulation of maternal process involved in parturition|upregulation of maternal process involved in parturition|up-regulation of maternal process involved in parturition|activation of maternal process involved in parturition http://purl.obolibrary.org/obo/GO_1904303 UBERON:2005227 biolink:AnatomicalEntity protoneuromast go-plus.json immature neuromast|proto neuromast|proto-neuromast http://purl.obolibrary.org/obo/UBERON_2005227 GO:1904302 biolink:BiologicalProcess negative regulation of maternal process involved in parturition Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition. go-plus.json downregulation of maternal process involved in parturition|down regulation of maternal process involved in parturition|inhibition of maternal process involved in parturition|down-regulation of maternal process involved in parturition http://purl.obolibrary.org/obo/GO_1904302 CHEBI:88048 biolink:ChemicalSubstance cyanotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_88048 GO:0062101 biolink:MolecularActivity peptidyl-aspartic acid 3-dioxygenase activity Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2. EC:1.14.11.16|MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN|RHEA:11508 go-plus.json peptide-aspartate beta-dioxygenase activity|aspartate beta-hydroxylase activity|aspartylpeptide beta-dioxygenase activity|peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|aspartyl/asparaginyl beta-hydroxylase activity http://purl.obolibrary.org/obo/GO_0062101 GO:1904301 biolink:BiologicalProcess regulation of maternal process involved in parturition Any process that modulates the frequency, rate or extent of maternal process involved in parturition. go-plus.json http://purl.obolibrary.org/obo/GO_1904301 GO:0062100 biolink:BiologicalProcess positive regulation of programmed necrotic cell death Any process that increases the frequency, rate or extent of programmed necrotic cell death. go-plus.json http://purl.obolibrary.org/obo/GO_0062100 GO:1904300 biolink:BiologicalProcess positive regulation of transcytosis Any process that activates or increases the frequency, rate or extent of transcytosis. go-plus.json up regulation of transcytosis|upregulation of transcytosis|up-regulation of transcytosis|activation of transcytosis http://purl.obolibrary.org/obo/GO_1904300 GO:0062103 biolink:BiologicalProcess double-stranded RNA biosynthetic process The chemical reactions and pathways resulting in the formation of double-stranded RNA. go-plus.json double-stranded RNA biosynthesis|dsRNA biosynthetic process|dsRNA biosynthesis http://purl.obolibrary.org/obo/GO_0062103 GO:1904310 biolink:BiologicalProcess cellular response to cordycepin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus. go-plus.json cellular response to 3'-deoxyadenosine http://purl.obolibrary.org/obo/GO_1904310 GO:0062102 biolink:BiologicalProcess female germline stem cell symmetric division Division of a female germline stem cell to produce two germline stem cells of the same type as the parent. go-plus.json http://purl.obolibrary.org/obo/GO_0062102 GO:0062105 biolink:MolecularActivity RNA 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide. RHEA:58956 go-plus.json http://purl.obolibrary.org/obo/GO_0062105 GO:0062104 biolink:MolecularActivity pumilio-response element binding Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA. go-plus.json PRE binding http://purl.obolibrary.org/obo/GO_0062104 GO:0062107 biolink:BiologicalProcess regulation of protein localization to non-growing cell tip Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip. go-plus.json http://purl.obolibrary.org/obo/GO_0062107 NCBITaxon:286 biolink:OrganismalEntity Pseudomonas go-plus.json RNA similarity group I|"Chlorobacterium" Guillebeau 1890, nom. rejic. Opin. 6 (not "Chlorobacterium" Lauterborn 1916)|Loefflerella|Liquidomonas http://purl.obolibrary.org/obo/NCBITaxon_286 GO:0062109 biolink:BiologicalProcess regulation of DNA recombinase disassembly Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0062109 GO:0062108 biolink:BiologicalProcess negative regulation of protein localization to non-growing cell tip Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip. go-plus.json http://purl.obolibrary.org/obo/GO_0062108 GO:0052791 biolink:MolecularActivity 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain. go-plus.json 2-keto-3-deoxynononic acid sialidase activity http://purl.obolibrary.org/obo/GO_0052791 GO:0052790 biolink:MolecularActivity chitooligosaccharide deacetylase activity Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions. EC:3.5.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0052790 CHEBI:39000 biolink:ChemicalSubstance sodium channel modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_39000 GO:0003748 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003748 GO:0052795 biolink:MolecularActivity exo-alpha-(2->6)-sialidase activity Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates. EC:3.2.1.18 go-plus.json exo-alpha-2,6-sialidase activity|exo-alpha-(2,6)-sialidase activity http://purl.obolibrary.org/obo/GO_0052795 GO:0003747 biolink:MolecularActivity translation release factor activity Involved in catalyzing the release of a nascent polypeptide chain from a ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0003747 GO:0052794 biolink:MolecularActivity exo-alpha-(2->3)-sialidase activity Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates. EC:3.2.1.18 go-plus.json exo-alpha-(2,3)-sialidase activity|exo-alpha-2,3-sialidase activity http://purl.obolibrary.org/obo/GO_0052794 GO:0052793 biolink:MolecularActivity pectin acetylesterase activity Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin. go-plus.json http://purl.obolibrary.org/obo/GO_0052793 GO:0003749 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0003749 GO:0052792 biolink:MolecularActivity endo-xylogalacturonan hydrolase activity Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position. go-plus.json endo-galacturonase activity http://purl.obolibrary.org/obo/GO_0052792 CHEBI:78605 biolink:ChemicalSubstance 7-oxolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78605 chebi_ph7_3 CHEBI:78604 biolink:ChemicalSubstance ursodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78604 chebi_ph7_3 CHEBI:78603 biolink:ChemicalSubstance 3beta-hydroxy-7-oxo-5beta-cholan-24-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78603 chebi_ph7_3 CHEBI:78608 biolink:ChemicalSubstance alpha-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78608 chebi_ph7_3 CHEBI:78607 biolink:ChemicalSubstance alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78607 chebi_ph7_3 NCBITaxon:122586 biolink:OrganismalEntity Neisseria meningitidis MC58 go-plus.json Neisseria meningitidis serogroup B strain MC58 http://purl.obolibrary.org/obo/NCBITaxon_122586 CHEBI:78602 biolink:ChemicalSubstance isoursodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78602 chebi_ph7_3 CHEBI:78601 biolink:ChemicalSubstance 11,21-dioxoprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_78601 chebi_ph7_3 CHEBI:78600 biolink:ChemicalSubstance 11-dehydrocorticosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_78600 chebi_ph7_3 CHEBI:78616 biolink:ChemicalSubstance carbohydrates and carbohydrate derivatives go-plus.json http://purl.obolibrary.org/obo/CHEBI_78616 CHEBI:78619 biolink:ChemicalSubstance iron(III) oxide-hydroxide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78619 chebi_ph7_3 CHEBI:78613 biolink:ChemicalSubstance C-terminal L-Ala-L-Leu-L-valinamide-N-CH=CH-S residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78613 chebi_ph7_3 CHEBI:78612 biolink:ChemicalSubstance C-terminal L-Cys-L-Leu-L-Val-L-Cys(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_78612 chebi_ph7_3 CHEBI:78611 biolink:ChemicalSubstance 3-hydroxybutanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78611 chebi_ph7_3 CHEBI:78628 biolink:ChemicalSubstance 2-hydroxyglutaryl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78628 chebi_ph7_3 CHEBI:78625 biolink:ChemicalSubstance clavaldehyde(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78625 chebi_ph7_3 CHEBI:78629 biolink:ChemicalSubstance N-(6-aminohexanoyl)-6-aminohexanoic acid zwitterion monomer go-plus.json http://purl.obolibrary.org/obo/CHEBI_78629 chebi_ph7_3 CHEBI:40096 biolink:ChemicalSubstance adenosine 5'-(hexahydrogen pentaphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_40096 CHEBI:78620 biolink:ChemicalSubstance 3-methoxy-5-methyl-1-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78620 chebi_ph7_3 CHEBI:78624 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_78624 CHEBI:78636 biolink:ChemicalSubstance vitexin 2''-O-beta-L-rhamnoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78636 chebi_ph7_3 CHEBI:146448 biolink:ChemicalSubstance beta-D-Xylp-(1->6)-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_146448 chebi_ph7_3 CHEBI:78631 biolink:ChemicalSubstance chroman-6-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_78631 chebi_ph7_3 CHEBI:78630 biolink:ChemicalSubstance 9-cis-retinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_78630 chebi_ph7_3 GO:0052700 biolink:BiologicalProcess ergothioneine catabolic process The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties. go-plus.json ergothioneine degradation|2-mercaptoergothioneine trimethylbetaine degradation|2-mercaptoergothioneine trimethylbetaine breakdown|ergothioneine breakdown|ergothioneine catabolism|2-mercaptoergothioneine trimethylbetaine catabolism|2-mercaptoergothioneine trimethylbetaine catabolic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate catabolic process http://purl.obolibrary.org/obo/GO_0052700 CHEBI:40070 biolink:ChemicalSubstance 4-hydroxycoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_40070 CHEBI:78647 biolink:ChemicalSubstance N-hexadecanoylsphinganine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78647 chebi_ph7_3 GO:0052704 biolink:BiologicalProcess ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate. Wikipedia:Ergothioneine go-plus.json ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine http://purl.obolibrary.org/obo/GO_0052704 GO:0052703 biolink:BiologicalProcess cellular modified histidine biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. go-plus.json cellular histidine derivative formation|cellular modified histidine biosynthesis|histidine derivative biosynthetic process|cellular modified histidine anabolism|cellular modified histidine synthesis|cellular modified histidine formation|cellular histidine derivative biosynthetic process|cellular histidine derivative biosynthesis|cellular histidine derivative anabolism|cellular histidine derivative synthesis http://purl.obolibrary.org/obo/GO_0052703 GO:0052702 biolink:BiologicalProcess cellular modified histidine catabolic process The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. go-plus.json modified histidine catabolic process|cellular modified histidine degradation|modified histidine catabolism|cellular modified histidine breakdown|histidine derivative catabolic process|cellular histidine derivative degradation|cellular histidine derivative breakdown|cellular histidine derivative catabolic process|cellular histidine derivative catabolism|cellular modified histidine catabolism http://purl.obolibrary.org/obo/GO_0052702 GO:0052701 biolink:BiologicalProcess cellular modified histidine metabolic process The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. go-plus.json cellular modified histidine metabolism|histidine derivative metabolic process|modified histidine metabolism|cellular histidine derivative metabolic process|modified histidine metabolic process|cellular histidine derivative metabolism http://purl.obolibrary.org/obo/GO_0052701 GO:0052708 biolink:BiologicalProcess N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine. go-plus.json hercynine metabolism|hercynine metabolic process|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolism|histidine betaine metabolism|histidine betaine metabolic process http://purl.obolibrary.org/obo/GO_0052708 GO:0052707 biolink:BiologicalProcess N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). KEGG_REACTION:R01169 go-plus.json histidine catabolism to hercynine|histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine|hercynine biosynthesis from histidine|histidine catabolic process to hercynine|histidine betaine biosynthesis from histidine http://purl.obolibrary.org/obo/GO_0052707 GO:0052706 biolink:MolecularActivity histidine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine. go-plus.json histidine methyltransferase activity|S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity|histidine-alpha-N-methyltransferase activity|S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052706 GO:0052705 biolink:MolecularActivity methylhistidine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine. go-plus.json S-adenosyl-L-methionine:alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|S-adenosyl-L-methionine:N-alpha-dimethyl-L-histidine N-alpha-methyltransferase activity|methylhistidine methyltransferase activity|histidine-alpha-N-methyltransferase activity http://purl.obolibrary.org/obo/GO_0052705 CHEBI:64005 biolink:ChemicalSubstance DHET go-plus.json http://purl.obolibrary.org/obo/CHEBI_64005 GO:0052709 biolink:BiologicalProcess N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine. go-plus.json hercynine formation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine synthesis|histidine betaine anabolism|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine formation|histidine betaine synthesis|histidine betaine formation|histidine betaine biosynthetic process|histidine betaine biosynthesis|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis|hercynine anabolism|hercynine synthesis|hercynine biosynthesis|hercynine biosynthetic process|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine anabolism http://purl.obolibrary.org/obo/GO_0052709 CHEBI:64009 biolink:ChemicalSubstance hydroperoxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64009 CHEBI:64008 biolink:ChemicalSubstance (8E,12Z)-10-hydroperoxy-8,12-octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64008 CHEBI:64007 biolink:ChemicalSubstance EET go-plus.json http://purl.obolibrary.org/obo/CHEBI_64007 CHEBI:64006 biolink:ChemicalSubstance (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64006 CHEBI:78640 biolink:ChemicalSubstance 7-O-methylvitexin 2''-O-beta-L-rhamnoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_78640 chebi_ph7_3 CHEBI:78646 biolink:ChemicalSubstance N-hexadecanoylsphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78646 chebi_ph7_3 GO:0052711 biolink:BiologicalProcess obsolete ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine OBSOLETE. The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). KEGG_REACTION:R04878 go-plus.json histidine betaine catabolism to ergothioneine|ergothioneine biosynthesis from hercynine|ergothioneine biosynthesis from histidine betaine|hercynine catabolism to ergothioneine|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism to ergothioneine http://purl.obolibrary.org/obo/GO_0052711 GO:0052710 biolink:BiologicalProcess N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine. go-plus.json N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine breakdown|histidine betaine breakdown|hercynine catabolism|histidine betaine catabolic process|hercynine degradation|hercynine breakdown|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine degradation|histidine betaine catabolism|hercynine catabolic process|histidine betaine degradation http://purl.obolibrary.org/obo/GO_0052710 NCBITaxon:209 biolink:OrganismalEntity Helicobacter go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_209 GO:0052715 biolink:MolecularActivity mannosyl-diinositol phosphorylceramide phospholipase activity Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0052715 GO:0052714 biolink:MolecularActivity mannosyl-inositol phosphorylceramide phospholipase activity Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0052714 GO:0052713 biolink:MolecularActivity inositol phosphorylceramide phospholipase activity Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0052713 GO:0052712 biolink:MolecularActivity inositol phosphosphingolipid phospholipase activity Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol. go-plus.json http://purl.obolibrary.org/obo/GO_0052712 CHEBI:39093 biolink:ChemicalSubstance organophosphorus pesticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_39093 GO:0052719 biolink:MolecularActivity apurinic/apyrimidinic endoribonuclease activity Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends. go-plus.json apurinic endoribonuclease activity|AP endoribonuclease activity|abasic endoribonuclease activity|apyrimidinic endoribonuclease activity http://purl.obolibrary.org/obo/GO_0052719 CHEBI:64012 biolink:ChemicalSubstance hydroperoxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_64012 GO:0052718 biolink:CellularComponent tRNA-specific adenosine-34 deaminase complex A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human. go-plus.json tRNA-A34 deaminase complex http://purl.obolibrary.org/obo/GO_0052718 CHEBI:64011 biolink:ChemicalSubstance (3Z)-2-oxohex-3-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_64011 chebi_ph7_3 GO:0052717 biolink:MolecularActivity tRNA-specific adenosine-34 deaminase activity Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule. go-plus.json tRNA(Ala)-A34 deaminase activity http://purl.obolibrary.org/obo/GO_0052717 GO:0052716 biolink:MolecularActivity hydroquinone:oxygen oxidoreductase activity Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O. RHEA:11276|MetaCyc:LACCASE-RXN|KEGG_REACTION:R00083|EC:1.10.3.2 go-plus.json p-diphenol:oxygen oxidoreductase activity|laccase reaction|benzenediol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0052716 CHEBI:64016 biolink:ChemicalSubstance (2E,4Z)-2-hydroxymuconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_64016 chebi_ph7_3 CHEBI:64014 biolink:ChemicalSubstance (5Z,8Z,10E,12E)-icosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_64014 CHEBI:64018 biolink:ChemicalSubstance protein kinase C agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_64018 CHEBI:64017 biolink:ChemicalSubstance (5Z,8Z,11Z,13E)-15-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_64017 CHEBI:78651 biolink:ChemicalSubstance N-acylphytosphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78651 chebi_ph7_3 CHEBI:78650 biolink:ChemicalSubstance N-hexadecanoylphytosphingosine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_78650 chebi_ph7_3 CHEBI:78657 biolink:ChemicalSubstance N-acylphytosphingosine-1-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78657 chebi_ph7_3 CHEBI:78656 biolink:ChemicalSubstance N-hexadecanoylphytosphingosine-1-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78656 chebi_ph7_3 CHEBI:78655 biolink:ChemicalSubstance N-acylsphinganine-1-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78655 chebi_ph7_3 CHEBI:78654 biolink:ChemicalSubstance N-hexadecanoylsphinganine-1-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_78654 chebi_ph7_3 GO:0032439 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032439 GO:0032438 biolink:BiologicalProcess melanosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. go-plus.json melanosome organisation|melanosome organization and biogenesis http://purl.obolibrary.org/obo/GO_0032438 GO:0032437 biolink:CellularComponent cuticular plate A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted. go-plus.json http://purl.obolibrary.org/obo/GO_0032437 GO:0032436 biolink:BiologicalProcess positive regulation of proteasomal ubiquitin-dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go-plus.json up-regulation of proteasomal ubiquitin-dependent protein catabolic process|upregulation of proteasomal ubiquitin-dependent protein catabolic process|up regulation of proteasomal ubiquitin-dependent protein catabolic process|activation of proteasomal ubiquitin-dependent protein catabolic process|stimulation of proteasomal ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_0032436 GO:0007479 biolink:BiologicalProcess leg disc proximal/distal pattern formation The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg. go-plus.json http://purl.obolibrary.org/obo/GO_0007479 GO:0032435 biolink:BiologicalProcess negative regulation of proteasomal ubiquitin-dependent protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go-plus.json down regulation of proteasomal ubiquitin-dependent protein catabolic process|downregulation of proteasomal ubiquitin-dependent protein catabolic process|down-regulation of proteasomal ubiquitin-dependent protein catabolic process|inhibition of proteasomal ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_0032435 GO:0007478 biolink:BiologicalProcess leg disc morphogenesis The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura. go-plus.json leg disc metamorphosis http://purl.obolibrary.org/obo/GO_0007478 GO:0007477 biolink:BiologicalProcess notum development The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007477 GO:0007476 biolink:BiologicalProcess imaginal disc-derived wing morphogenesis The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying. go-plus.json wing morphogenesis http://purl.obolibrary.org/obo/GO_0007476 GO:0007475 biolink:BiologicalProcess apposition of dorsal and ventral imaginal disc-derived wing surfaces The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing. go-plus.json apposition of dorsal and ventral wing surfaces http://purl.obolibrary.org/obo/GO_0007475 CHEBI:79081 biolink:ChemicalSubstance cyclic 2,3-bisphospho-D-glycerate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79081 chebi_ph7_3 GO:0007474 biolink:BiologicalProcess imaginal disc-derived wing vein specification The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified. go-plus.json wing vein specification http://purl.obolibrary.org/obo/GO_0007474 CHEBI:79080 biolink:ChemicalSubstance lactose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79080 chebi_ph7_3 GO:0007473 biolink:BiologicalProcess wing disc proximal/distal pattern formation The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing. go-plus.json http://purl.obolibrary.org/obo/GO_0007473 GO:0007472 biolink:BiologicalProcess wing disc morphogenesis The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura. go-plus.json wing disc metamorphosis http://purl.obolibrary.org/obo/GO_0007472 PR:000006165 biolink:Protein C-C motif chemokine 12 An eotaxin-like cytokine that is a translation product of the mouse Ccl12 gene or a 1:1 ortholog thereof. go-plus.json Mcp5|Scya12|MCP-1-related chemokine|small-inducible cytokine A12|Ccl12|monocyte chemoattractant protein 5|MCP-5|monocyte chemotactic protein 5 http://purl.obolibrary.org/obo/PR_000006165 GO:0007471 biolink:BiologicalProcess obsolete prothoracic morphogenesis OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized. go-plus.json prothoracic morphogenesis http://purl.obolibrary.org/obo/GO_0007471 GO:0007481 biolink:BiologicalProcess haltere disc morphogenesis The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. go-plus.json haltere disc metamorphosis http://purl.obolibrary.org/obo/GO_0007481 CHEBI:79074 biolink:ChemicalSubstance 1,2-dicapryl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79074 GO:0007480 biolink:BiologicalProcess imaginal disc-derived leg morphogenesis The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007480 CHEBI:79072 biolink:ChemicalSubstance 15-ketoprostaglandin F1alpha(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79072 chebi_ph7_3 NCBITaxon:13 biolink:OrganismalEntity Dictyoglomus go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_13 CHEBI:79071 biolink:ChemicalSubstance selenoneine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79071 chebi_ph7_3 CHEBI:79077 biolink:ChemicalSubstance 5-hydroxy-3-methyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79077 CHEBI:79076 biolink:ChemicalSubstance 3-methyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79076 CHEBI:79075 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79075 GO:0032434 biolink:BiologicalProcess regulation of proteasomal ubiquitin-dependent protein catabolic process Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. go-plus.json http://purl.obolibrary.org/obo/GO_0032434 GO:0032433 biolink:CellularComponent filopodium tip The end of a filopodium distal to the body of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0032433 GO:0032432 biolink:CellularComponent actin filament bundle An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. go-plus.json actin cable http://purl.obolibrary.org/obo/GO_0032432 GO:0032431 biolink:BiologicalProcess activation of phospholipase A2 activity Any process that initiates the activity of the inactive enzyme phospholipase A2. go-plus.json phospholipase A2 activation http://purl.obolibrary.org/obo/GO_0032431 CHEBI:79079 biolink:ChemicalSubstance (4S)-4-hydroxy-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79079 GO:0032430 biolink:BiologicalProcess positive regulation of phospholipase A2 activity Any process that activates or increases the activity of the enzyme phospholipase A2. go-plus.json upregulation of phospholipase A2 activity|up regulation of phospholipase A2 activity|activation of phospholipase A2 activity|stimulation of phospholipase A2 activity|up-regulation of phospholipase A2 activity http://purl.obolibrary.org/obo/GO_0032430 GO:0032429 biolink:BiologicalProcess regulation of phospholipase A2 activity Any process that modulates the activity of the enzyme phospholipase A2. go-plus.json http://purl.obolibrary.org/obo/GO_0032429 GO:0032428 biolink:MolecularActivity beta-N-acetylgalactosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides. MetaCyc:3.2.1.53-RXN|EC:3.2.1.53 go-plus.json http://purl.obolibrary.org/obo/GO_0032428 GO:0032427 biolink:MolecularActivity GBD domain binding Binding to a GTPase protein binding domain (GDB) domain. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac. go-plus.json PMD binding|Cdc42/Rac interactive binding motif binding|CRIB motif binding|P21-Rho-binding domain binding http://purl.obolibrary.org/obo/GO_0032427 CHEBI:137150 biolink:ChemicalSubstance (R)-5-[2-(methylthio)ethyl]hydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_137150 chebi_ph7_3 GO:0032426 biolink:CellularComponent stereocilium tip A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0032426 GO:0032425 biolink:BiologicalProcess positive regulation of mismatch repair Any process that activates or increases the frequency, rate or extent of mismatch repair. go-plus.json up regulation of mismatch repair|activation of mismatch repair|stimulation of mismatch repair|up-regulation of mismatch repair|upregulation of mismatch repair http://purl.obolibrary.org/obo/GO_0032425 GO:0032424 biolink:BiologicalProcess negative regulation of mismatch repair Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair. go-plus.json down-regulation of mismatch repair|inhibition of mismatch repair|down regulation of mismatch repair|downregulation of mismatch repair http://purl.obolibrary.org/obo/GO_0032424 GO:0007489 biolink:BiologicalProcess maintenance of imaginal histoblast diploidy The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells. go-plus.json http://purl.obolibrary.org/obo/GO_0007489 GO:0007488 biolink:BiologicalProcess histoblast morphogenesis The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen. go-plus.json histoblast metamorphosis http://purl.obolibrary.org/obo/GO_0007488 GO:0007487 biolink:BiologicalProcess analia development The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007487 GO:0007486 biolink:BiologicalProcess imaginal disc-derived female genitalia development The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster. go-plus.json female genital development http://purl.obolibrary.org/obo/GO_0007486 GO:0007485 biolink:BiologicalProcess imaginal disc-derived male genitalia development The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster. go-plus.json male genital development http://purl.obolibrary.org/obo/GO_0007485 GO:0007484 biolink:BiologicalProcess imaginal disc-derived genitalia development The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster. go-plus.json genital development http://purl.obolibrary.org/obo/GO_0007484 CHEBI:79091 biolink:ChemicalSubstance EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_79091 GO:0007483 biolink:BiologicalProcess genital disc morphogenesis The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut. go-plus.json genital disc metamorphosis http://purl.obolibrary.org/obo/GO_0007483 GO:0007482 biolink:BiologicalProcess haltere development The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings. go-plus.json http://purl.obolibrary.org/obo/GO_0007482 GO:0007492 biolink:BiologicalProcess endoderm development The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0007492 NCBITaxon:22 biolink:OrganismalEntity Shewanella go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_22 GO:0007491 biolink:BiologicalProcess sternite morphogenesis The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment. go-plus.json http://purl.obolibrary.org/obo/GO_0007491 CHEBI:79084 biolink:ChemicalSubstance tricyclic diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79084 GO:0007490 biolink:BiologicalProcess tergite morphogenesis The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment. go-plus.json http://purl.obolibrary.org/obo/GO_0007490 CHEBI:79083 biolink:ChemicalSubstance 3-hydroxy-5-methyl-1-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79083 CHEBI:79082 biolink:ChemicalSubstance 5-methyl-1-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79082 GO:0032423 biolink:BiologicalProcess regulation of mismatch repair Any process that modulates the frequency, rate or extent of mismatch repair. go-plus.json http://purl.obolibrary.org/obo/GO_0032423 GO:0032422 biolink:MolecularActivity purine-rich negative regulatory element binding Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes. go-plus.json PNR element binding http://purl.obolibrary.org/obo/GO_0032422 GO:0032421 biolink:CellularComponent stereocilium bundle A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes. go-plus.json stereocilia bundle http://purl.obolibrary.org/obo/GO_0032421 goslim_pir GO:0032420 biolink:CellularComponent stereocilium An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles. go-plus.json http://purl.obolibrary.org/obo/GO_0032420 SO:0005836 biolink:SequenceFeature regulatory_region A region of sequence that is involved in the control of a biological process. http://en.wikipedia.org/wiki/Regulatory_region go-plus.json regulatory region|INSDC_qualifier:other|INSDC_feature:regulatory http://purl.obolibrary.org/obo/SO_0005836 SOFA CHEBI:137145 biolink:ChemicalSubstance 15-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137145 GO:0032419 biolink:CellularComponent extrinsic component of lysosome membrane The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to lysosome membrane|extrinsic to lysosomal membrane http://purl.obolibrary.org/obo/GO_0032419 GO:0032418 biolink:BiologicalProcess lysosome localization Any process in which a lysosome is transported to, and/or maintained in, a specific location. go-plus.json lysosome localisation http://purl.obolibrary.org/obo/GO_0032418 GO:0032417 biolink:BiologicalProcess positive regulation of sodium:proton antiporter activity Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). go-plus.json upregulation of sodium:hydrogen antiporter activity|up regulation of sodium:hydrogen antiporter activity|positive regulation of sodium:hydrogen antiporter activity|activation of sodium:hydrogen antiporter activity|stimulation of sodium:hydrogen antiporter activity|up-regulation of sodium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0032417 GO:0032416 biolink:BiologicalProcess negative regulation of sodium:proton antiporter activity Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). go-plus.json down regulation of sodium:hydrogen antiporter activity|downregulation of sodium:hydrogen antiporter activity|down-regulation of sodium:hydrogen antiporter activity|negative regulation of sodium:hydrogen antiporter activity|inhibition of sodium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0032416 GO:0032415 biolink:BiologicalProcess regulation of sodium:proton antiporter activity Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). go-plus.json regulation of sodium:hydrogen antiporter activity http://purl.obolibrary.org/obo/GO_0032415 GO:0007459 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007459 GO:0032414 biolink:BiologicalProcess positive regulation of ion transmembrane transporter activity Any process that activates or increases the activity of an ion transporter. go-plus.json stimulation of ion transporter activity|up-regulation of ion transporter activity|activation of ion transporter activity|positive regulation of ion transporter activity|up regulation of ion transporter activity|upregulation of ion transporter activity http://purl.obolibrary.org/obo/GO_0032414 GO:0007458 biolink:BiologicalProcess progression of morphogenetic furrow involved in compound eye morphogenesis The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc. go-plus.json progression of morphogenetic furrow during compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0007458 GO:0032413 biolink:BiologicalProcess negative regulation of ion transmembrane transporter activity Any process that stops or reduces the activity of an ion transporter. go-plus.json negative regulation of ion transporter activity|down-regulation of ion transporter activity|downregulation of ion transporter activity|down regulation of ion transporter activity|inhibition of ion transporter activity http://purl.obolibrary.org/obo/GO_0032413 GO:0007457 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007457 GO:0007456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007456 GO:0007455 biolink:BiologicalProcess eye-antennal disc morphogenesis The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps. go-plus.json eye-antennal disc metamorphosis http://purl.obolibrary.org/obo/GO_0007455 GO:0007454 biolink:BiologicalProcess labial disc morphogenesis The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis. go-plus.json labial disc metamorphosis http://purl.obolibrary.org/obo/GO_0007454 GO:0007453 biolink:BiologicalProcess clypeo-labral disc morphogenesis The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus. go-plus.json clypeo-labral disc metamorphosis|morphogenesis of structures derived from the clypeo-labral disc http://purl.obolibrary.org/obo/GO_0007453 GO:0007452 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007452 GO:0007451 biolink:BiologicalProcess dorsal/ventral lineage restriction, imaginal disc Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment. go-plus.json dorsoventral lineage restriction, imaginal disc|dorsal-ventral lineage restriction, imaginal disc http://purl.obolibrary.org/obo/GO_0007451 GO:0007450 biolink:BiologicalProcess dorsal/ventral pattern formation, imaginal disc The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed. go-plus.json dorsoventral pattern formation, imaginal disc|dorsal-ventral pattern formation, imaginal disc http://purl.obolibrary.org/obo/GO_0007450 CHEBI:79096 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79096 CHEBI:137117 biolink:ChemicalSubstance (S)-5-[2-(methylthio)ethyl]hydantoin go-plus.json http://purl.obolibrary.org/obo/CHEBI_137117 chebi_ph7_3 CHEBI:79095 biolink:ChemicalSubstance N(5)-hydroxy-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79095 CHEBI:137116 biolink:ChemicalSubstance N-carbamoyl-L-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137116 chebi_ph7_3 CHEBI:79099 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79099 CHEBI:79098 biolink:ChemicalSubstance 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79098 CHEBI:79097 biolink:ChemicalSubstance 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79097 CHEBI:137110 biolink:ChemicalSubstance 17beta-hydroxy-5alpha-estr-1(10)-en-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_137110 chebi_ph7_3 GO:0032412 biolink:BiologicalProcess regulation of ion transmembrane transporter activity Any process that modulates the activity of an ion transporter. go-plus.json regulation of ion transporter activity http://purl.obolibrary.org/obo/GO_0032412 GO:0032411 biolink:BiologicalProcess positive regulation of transporter activity Any process that activates or increases the activity of a transporter. go-plus.json up regulation of transporter activity|upregulation of transporter activity|stimulation of transporter activity|up-regulation of transporter activity|activation of transporter activity http://purl.obolibrary.org/obo/GO_0032411 GO:0032410 biolink:BiologicalProcess negative regulation of transporter activity Any process that stops or reduces the activity of a transporter. go-plus.json down-regulation of transporter activity|downregulation of transporter activity|down regulation of transporter activity|inhibition of transporter activity http://purl.obolibrary.org/obo/GO_0032410 CHEBI:137112 biolink:ChemicalSubstance 12-hydroxy-(5Z,8Z,10E,14Z)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137112 CHEBI:137111 biolink:ChemicalSubstance 5-hydroxy-(6E,8Z,11Z,14Z)-icosatetraenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137111 GO:0032409 biolink:BiologicalProcess regulation of transporter activity Any process that modulates the activity of a transporter. go-plus.json http://purl.obolibrary.org/obo/GO_0032409 GO:0032408 biolink:MolecularActivity MutSbeta complex binding Binding to a MutSbeta mismatch repair complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032408 GO:0032407 biolink:MolecularActivity MutSalpha complex binding Binding to a MutSalpha mismatch repair complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032407 GO:0032406 biolink:MolecularActivity MutLbeta complex binding Binding to a MutLbeta mismatch repair complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032406 GO:0032405 biolink:MolecularActivity MutLalpha complex binding Binding to a MutLalpha mismatch repair complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032405 GO:0032404 biolink:MolecularActivity mismatch repair complex binding Binding to a mismatch repair complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032404 GO:0032403 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032403 GO:0007469 biolink:BiologicalProcess antennal development The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0007469 GO:0032402 biolink:BiologicalProcess melanosome transport The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032402 GO:0007468 biolink:BiologicalProcess obsolete regulation of rhodopsin gene expression OBSOLETE. Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation. go-plus.json regulation of rhodopsin gene activity http://purl.obolibrary.org/obo/GO_0007468 GO:0007467 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007467 GO:0007466 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007466 GO:0007465 biolink:BiologicalProcess R7 cell fate commitment The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium. go-plus.json http://purl.obolibrary.org/obo/GO_0007465 GO:0007464 biolink:BiologicalProcess R3/R4 cell fate commitment The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres. go-plus.json http://purl.obolibrary.org/obo/GO_0007464 GO:0007463 biolink:BiologicalProcess R2/R5 cell fate commitment The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres. go-plus.json http://purl.obolibrary.org/obo/GO_0007463 GO:0007462 biolink:BiologicalProcess R1/R6 cell fate commitment The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres. go-plus.json http://purl.obolibrary.org/obo/GO_0007462 GO:0007461 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007461 GO:0007460 biolink:BiologicalProcess R8 cell fate commitment The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium. go-plus.json restriction of R8 fate http://purl.obolibrary.org/obo/GO_0007460 GO:0007470 biolink:BiologicalProcess prothoracic disc morphogenesis The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle. go-plus.json prothoracic disc metamorphosis http://purl.obolibrary.org/obo/GO_0007470 GO:0032401 biolink:BiologicalProcess establishment of melanosome localization The directed movement of a melanosome to a specific location. go-plus.json establishment of melanosome localisation http://purl.obolibrary.org/obo/GO_0032401 GO:0032400 biolink:BiologicalProcess melanosome localization Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell. go-plus.json melanosome localisation http://purl.obolibrary.org/obo/GO_0032400 GO:0007439 biolink:BiologicalProcess ectodermal digestive tract development The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. go-plus.json ectodermal gut development http://purl.obolibrary.org/obo/GO_0007439 GO:0007438 biolink:BiologicalProcess oenocyte development The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. go-plus.json http://purl.obolibrary.org/obo/GO_0007438 GO:0007437 biolink:BiologicalProcess adult salivary gland morphogenesis The process in which the anatomical structures of the adult salivary gland are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0007437 GO:0007436 biolink:BiologicalProcess larval salivary gland morphogenesis The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0007436 GO:0007435 biolink:BiologicalProcess salivary gland morphogenesis The process in which the anatomical structures of the salivary gland are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0007435 GO:0007434 biolink:BiologicalProcess adult salivary gland boundary specification Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland. go-plus.json larval salivary gland determination http://purl.obolibrary.org/obo/GO_0007434 GO:0007433 biolink:BiologicalProcess larval salivary gland boundary specification Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland. go-plus.json larval salivary gland determination http://purl.obolibrary.org/obo/GO_0007433 GO:0007432 biolink:BiologicalProcess salivary gland boundary specification Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland. go-plus.json salivary gland determination http://purl.obolibrary.org/obo/GO_0007432 GO:0007431 biolink:BiologicalProcess salivary gland development The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0007431 GO:0007430 biolink:BiologicalProcess terminal branching, open tracheal system Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster. go-plus.json terminal branching of trachea, cytoplasmic projection extension http://purl.obolibrary.org/obo/GO_0007430 CHEBI:176783 biolink:ChemicalSubstance vitamin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_176783 GO:0007449 biolink:BiologicalProcess proximal/distal pattern formation, imaginal disc The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed. go-plus.json http://purl.obolibrary.org/obo/GO_0007449 GO:0007448 biolink:BiologicalProcess anterior/posterior pattern specification, imaginal disc The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form. go-plus.json http://purl.obolibrary.org/obo/GO_0007448 GO:0007447 biolink:BiologicalProcess imaginal disc pattern formation The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. go-plus.json http://purl.obolibrary.org/obo/GO_0007447 GO:0007446 biolink:BiologicalProcess imaginal disc growth The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. go-plus.json http://purl.obolibrary.org/obo/GO_0007446 GO:0007445 biolink:BiologicalProcess determination of imaginal disc primordium Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0007445 GO:0007444 biolink:BiologicalProcess imaginal disc development The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.). go-plus.json http://purl.obolibrary.org/obo/GO_0007444 GO:0007443 biolink:BiologicalProcess Malpighian tubule morphogenesis The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. go-plus.json http://purl.obolibrary.org/obo/GO_0007443 GO:0007442 biolink:BiologicalProcess hindgut morphogenesis The process in which the anatomical structures of the hindgut are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0007442 GO:0007441 biolink:BiologicalProcess anterior midgut (ectodermal) morphogenesis The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0007441 CHEBI:127780 biolink:ChemicalSubstance phosphonoformic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_127780 GO:0007440 biolink:BiologicalProcess foregut morphogenesis The process in which the anatomical structures of the foregut are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0007440 CHEBI:127781 biolink:ChemicalSubstance 17-(4-hydroxyphenyl)heptadecanoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_127781 CHEBI:137107 biolink:ChemicalSubstance 5,6-epoxy-(8Z,11Z,14Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137107 CHEBI:137106 biolink:ChemicalSubstance 5-[(9Z)-octadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137106 CHEBI:137109 biolink:ChemicalSubstance (2xi)-3-deoxy-7-O-phospho-beta-D-threo-hept-6-ulopyranosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137109 CHEBI:137108 biolink:ChemicalSubstance 5-dehydro-L-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137108 chebi_ph7_3 CHEBI:137103 biolink:ChemicalSubstance phosphatidic acid 32:7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137103 CHEBI:137102 biolink:ChemicalSubstance 5-[(9Z)-hexadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137102 GO:0007419 biolink:BiologicalProcess ventral cord development The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms. go-plus.json http://purl.obolibrary.org/obo/GO_0007419 GO:0007418 biolink:BiologicalProcess ventral midline development The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. go-plus.json http://purl.obolibrary.org/obo/GO_0007418 GO:0007417 biolink:BiologicalProcess central nervous system development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. Wikipedia:Neural_development go-plus.json CNS development http://purl.obolibrary.org/obo/GO_0007417 NCBITaxon:211586 biolink:OrganismalEntity Shewanella oneidensis MR-1 go-plus.json Shewanella oneidensis strain MR-1|Shewanella oneidensis str. MR-1|Shewanella oneidensis ATCC 700550|Shewanella sp. MR-1 http://purl.obolibrary.org/obo/NCBITaxon_211586 GO:0007416 biolink:BiologicalProcess synapse assembly The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). Wikipedia:Synaptogenesis go-plus.json synapse biogenesis|synaptogenesis http://purl.obolibrary.org/obo/GO_0007416 goslim_synapse GO:0007415 biolink:BiologicalProcess defasciculation of motor neuron axon Separation of a motor axon away from a bundle of axons known as a fascicle. go-plus.json http://purl.obolibrary.org/obo/GO_0007415 GO:0007414 biolink:BiologicalProcess axonal defasciculation Separation of axons away from a bundle of axons known as a fascicle. go-plus.json defasciculation of neuron http://purl.obolibrary.org/obo/GO_0007414 GO:0007413 biolink:BiologicalProcess axonal fasciculation The collection of axons into a bundle of rods, known as a fascicle. go-plus.json fasciculation of neuron http://purl.obolibrary.org/obo/GO_0007413 GO:0007412 biolink:BiologicalProcess axon target recognition The process in which an axon recognizes and binds to a set of cells with which it may form stable connections. go-plus.json http://purl.obolibrary.org/obo/GO_0007412 GO:0007411 biolink:BiologicalProcess axon guidance The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. Wikipedia:Axon_guidance go-plus.json axon growth cone guidance|axon chemotaxis|axon pathfinding http://purl.obolibrary.org/obo/GO_0007411 GO:0007410 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007410 GO:0007429 biolink:BiologicalProcess secondary branching, open tracheal system Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster. go-plus.json secondary tracheal branching http://purl.obolibrary.org/obo/GO_0007429 GO:0007428 biolink:BiologicalProcess primary branching, open tracheal system Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster. go-plus.json primary tracheal branching http://purl.obolibrary.org/obo/GO_0007428 GO:0007427 biolink:BiologicalProcess epithelial cell migration, open tracheal system The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster. go-plus.json tracheal cell migration|tracheal epithelial cell migration http://purl.obolibrary.org/obo/GO_0007427 GO:0007426 biolink:BiologicalProcess tracheal outgrowth, open tracheal system The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007426 GO:0007425 biolink:BiologicalProcess epithelial cell fate determination, open tracheal system The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster. go-plus.json tracheal placode cell fate determination|tracheal epithelial cell fate determination|tracheal cell fate determination http://purl.obolibrary.org/obo/GO_0007425 GO:0007424 biolink:BiologicalProcess open tracheal system development The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007424 GO:0007423 biolink:BiologicalProcess sensory organ development The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. go-plus.json sense organ development http://purl.obolibrary.org/obo/GO_0007423 GO:0007422 biolink:BiologicalProcess peripheral nervous system development The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. go-plus.json http://purl.obolibrary.org/obo/GO_0007422 GO:0007421 biolink:BiologicalProcess stomatogastric nervous system development The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007421 GO:0007420 biolink:BiologicalProcess brain development The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). go-plus.json http://purl.obolibrary.org/obo/GO_0007420 CHEBI:31082 biolink:ChemicalSubstance 2-hydroxy-6-oxonona-2,4,7-trienedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31082 CHEBI:31080 biolink:ChemicalSubstance 2-hydroxy-2,3-dihydrogenistein go-plus.json http://purl.obolibrary.org/obo/CHEBI_31080 chebi_ph7_3 CHEBI:31087 biolink:ChemicalSubstance 2-phytyl-1,4-naphthoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_31087 chebi_ph7_3 CHEBI:79005 biolink:ChemicalSubstance diphthine methyl ester residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_79005 chebi_ph7_3 CHEBI:79008 biolink:ChemicalSubstance (R)-nicotinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79008 chebi_ph7_3 CHEBI:79007 biolink:ChemicalSubstance tricosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79007 chebi_ph7_3 GO:0032492 biolink:BiologicalProcess detection of molecule of oomycetes origin The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal. go-plus.json detection of oomycetes associated molecule http://purl.obolibrary.org/obo/GO_0032492 GO:0032491 biolink:BiologicalProcess detection of molecule of fungal origin The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal. go-plus.json detection of fungal associated molecule|detection of fungus associated molecule http://purl.obolibrary.org/obo/GO_0032491 GO:0032490 biolink:BiologicalProcess detection of molecule of bacterial origin The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal. go-plus.json detection of bacteria associated molecule|detection of bacterium associated molecule|detection of bacterial associated molecule http://purl.obolibrary.org/obo/GO_0032490 CHEBI:79010 biolink:ChemicalSubstance prostaglandin D1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79010 chebi_ph7_3 CHEBI:137198 biolink:ChemicalSubstance phosphatidylglycerol 37:4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137198 GO:0032499 biolink:BiologicalProcess detection of peptidoglycan The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0032499 GO:0032498 biolink:BiologicalProcess detection of muramyl dipeptide The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0032498 GO:0032497 biolink:BiologicalProcess detection of lipopolysaccharide The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. go-plus.json detection of LPS http://purl.obolibrary.org/obo/GO_0032497 CHEBI:137195 biolink:ChemicalSubstance phosphatidylglycerol 43:6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137195 GO:0032496 biolink:BiologicalProcess response to lipopolysaccharide Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. go-plus.json response to LPS|response to endotoxin http://purl.obolibrary.org/obo/GO_0032496 GO:0032495 biolink:BiologicalProcess response to muramyl dipeptide Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0032495 GO:0032494 biolink:BiologicalProcess response to peptidoglycan Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0032494 GO:0032493 biolink:BiologicalProcess response to bacterial lipoprotein Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032493 GO:0032481 biolink:BiologicalProcess positive regulation of type I interferon production Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json upregulation of type I interferon production|stimulation of type I interferon production|up-regulation of type I interferon production|positive regulation of type I IFN production|activation of type I interferon production|up regulation of type I interferon production http://purl.obolibrary.org/obo/GO_0032481 GO:0032480 biolink:BiologicalProcess negative regulation of type I interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json down regulation of type I interferon production|inhibition of type I interferon production|negative regulation of type I IFN production|down-regulation of type I interferon production|downregulation of type I interferon production http://purl.obolibrary.org/obo/GO_0032480 CHEBI:79021 biolink:ChemicalSubstance (11Z)-3-oxohexadecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79021 chebi_ph7_3 CHEBI:79020 biolink:ChemicalSubstance alpha,beta-unsaturated monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79020 GO:0032489 biolink:BiologicalProcess regulation of Cdc42 protein signal transduction Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0032489 GO:0032488 biolink:BiologicalProcess Cdc42 protein signal transduction A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. go-plus.json cdc42 signalling pathway|Cdc42 signaling pathway|Cdc42 signaling http://purl.obolibrary.org/obo/GO_0032488 GO:0032487 biolink:BiologicalProcess regulation of Rap protein signal transduction Any process that modulates the frequency, rate or extent of Rap protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0032487 GO:0032486 biolink:BiologicalProcess Rap protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state. go-plus.json http://purl.obolibrary.org/obo/GO_0032486 GO:0032485 biolink:BiologicalProcess regulation of Ral protein signal transduction Any process that modulates the frequency, rate or extent of Ral protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0032485 GO:0032484 biolink:BiologicalProcess Ral protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state. go-plus.json http://purl.obolibrary.org/obo/GO_0032484 GO:0032483 biolink:BiologicalProcess regulation of Rab protein signal transduction Any process that modulates the frequency, rate or extent of Rab protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0032483 GO:0032482 biolink:BiologicalProcess Rab protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. go-plus.json http://purl.obolibrary.org/obo/GO_0032482 CHEBI:137183 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19S,20R)-19,20-epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137183 CHEBI:137182 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137182 chebi_ph7_3 GO:0032479 biolink:BiologicalProcess regulation of type I interferon production Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json regulation of type I IFN production http://purl.obolibrary.org/obo/GO_0032479 CHEBI:137180 biolink:ChemicalSubstance 2,3-diacyl-alpha-D-glucosaminyl 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137180 chebi_ph7_3 CHEBI:80029 biolink:ChemicalSubstance epothilone C go-plus.json http://purl.obolibrary.org/obo/CHEBI_80029 chebi_ph7_3 GO:0032470 biolink:BiologicalProcess positive regulation of endoplasmic reticulum calcium ion concentration Any process that increases the concentration of calcium ions in the endoplasmic reticulum. go-plus.json elevation of endoplasmic reticulum calcium ion concentration|elevation of calcium ion concentration in endoplasmic reticulum|elevation of ER calcium ion concentration|endoplasmic reticulum calcium ion concentration elevation http://purl.obolibrary.org/obo/GO_0032470 CHEBI:79034 biolink:ChemicalSubstance monacolin J go-plus.json http://purl.obolibrary.org/obo/CHEBI_79034 chebi_ph7_3 CHEBI:79032 biolink:ChemicalSubstance O-[S-(dihydromonacolin L carboxy)pantetheine-4'-phosphoryl]-L-serine(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_79032 chebi_ph7_3 CHEBI:79031 biolink:ChemicalSubstance dihydromonacolin L carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79031 chebi_ph7_3 GO:0032478 biolink:CellularComponent heterotetrameric decaprenyl diphosphate synthase complex A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1. go-plus.json http://purl.obolibrary.org/obo/GO_0032478 CHEBI:79038 biolink:ChemicalSubstance mevinolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79038 chebi_ph7_3 GO:0032477 biolink:CellularComponent homodimeric decaprenyl diphosphate synthase complex A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032477 GO:0032476 biolink:CellularComponent decaprenyl diphosphate synthase complex A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032476 goslim_pir CHEBI:79036 biolink:ChemicalSubstance 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79036 chebi_ph7_3 GO:0032475 biolink:BiologicalProcess otolith formation The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts. go-plus.json http://purl.obolibrary.org/obo/GO_0032475 CHEBI:79035 biolink:ChemicalSubstance monacolin J carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79035 chebi_ph7_3 GO:0032474 biolink:BiologicalProcess otolith morphogenesis The process in which the anatomical structures of an otolith are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0032474 GO:0032473 biolink:CellularComponent cytoplasmic side of mitochondrial outer membrane The external (cytoplasmic) face of the mitochondrial outer membrane. go-plus.json external side of mitochondrial outer membrane|external side of mitochondrial envelope|cytosolic side of mitochondrial outer membrane|external leaflet of mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0032473 CHEBI:137179 biolink:ChemicalSubstance UDP-2,3-diacyl-alpha-D-glucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137179 chebi_ph7_3 GO:0032472 biolink:BiologicalProcess Golgi calcium ion transport The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. go-plus.json Golgi calcium transport http://purl.obolibrary.org/obo/GO_0032472 GO:0032471 biolink:BiologicalProcess negative regulation of endoplasmic reticulum calcium ion concentration Any process that decreases the concentration of calcium ions in the endoplasmic reticulum. go-plus.json reduction of ER calcium ion concentration|endoplasmic reticulum calcium ion concentration reduction|ER calcium ion concentration reduction|reduction of endoplasmic reticulum calcium ion concentration|reduction of calcium ion concentration in endoplasmic reticulum|reduction of calcium ion concentration in ER http://purl.obolibrary.org/obo/GO_0032471 PR:000021742 biolink:Protein thyrotropin subunit beta proteolytic cleavage product A thyrotropin subunit beta that has been processed by proteolytic cleavage. go-plus.json TSHB/ClvPrd http://purl.obolibrary.org/obo/PR_000021742 CHEBI:137193 biolink:ChemicalSubstance (5Z,11Z,14Z,17Z)-8,9-epoxyicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137193 GO:0032469 biolink:BiologicalProcess endoplasmic reticulum calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings. go-plus.json regulation of ER calcium ion concentration|regulation of endoplasmic reticulum calcium ion concentration|ER calcium ion concentration regulation|endoplasmic reticulum calcium ion concentration regulation|regulation of calcium ion concentration in ER|calcium ion homeostasis in endoplasmic reticulum|ER calcium ion homeostasis|calcium ion homeostasis in ER|regulation of calcium ion concentration in endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0032469 GO:0032468 biolink:BiologicalProcess Golgi calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. go-plus.json regulation of calcium ion concentration in Golgi|regulation of Golgi calcium ion concentration|calcium ion homeostasis in Golgi|Golgi calcium ion concentration regulation http://purl.obolibrary.org/obo/GO_0032468 CHEBI:79044 biolink:ChemicalSubstance monacolin L carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79044 chebi_ph7_3 CHEBI:137187 biolink:ChemicalSubstance 15(S)-HPETE 2-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_137187 chebi_ph7_3 GO:0032467 biolink:BiologicalProcess positive regulation of cytokinesis Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells. go-plus.json up regulation of cytokinesis|activation of cytokinesis|stimulation of cytokinesis|positive regulation of cell cycle cytokinesis|up-regulation of cytokinesis|upregulation of cytokinesis http://purl.obolibrary.org/obo/GO_0032467 CHEBI:79049 biolink:ChemicalSubstance L-glucopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79049 CHEBI:137186 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137186 chebi_ph7_3 GO:0032466 biolink:BiologicalProcess negative regulation of cytokinesis Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells. go-plus.json down-regulation of cytokinesis|negative regulation of cell cycle cytokinesis|inhibition of cytokinesis|down regulation of cytokinesis|downregulation of cytokinesis http://purl.obolibrary.org/obo/GO_0032466 CHEBI:79048 biolink:ChemicalSubstance L-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79048 GO:0032465 biolink:BiologicalProcess regulation of cytokinesis Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells. go-plus.json regulation of cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_0032465 CHEBI:137185 biolink:ChemicalSubstance PA(18:0/18:3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137185 CHEBI:79047 biolink:ChemicalSubstance D-mannopyranuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79047 GO:0032464 biolink:BiologicalProcess positive regulation of protein homooligomerization Any process that activates or increases the frequency, rate or extent of protein homooligomerization. go-plus.json activation of protein homooligomerization|stimulation of protein homooligomerization|up-regulation of protein homooligomerization|upregulation of protein homooligomerization|induction of protein homooligomerization|up regulation of protein homooligomerization http://purl.obolibrary.org/obo/GO_0032464 GO:0032463 biolink:BiologicalProcess negative regulation of protein homooligomerization Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization. go-plus.json down-regulation of protein homooligomerization|inhibition of protein homooligomerization|down regulation of protein homooligomerization|downregulation of protein homooligomerization http://purl.obolibrary.org/obo/GO_0032463 GO:0032462 biolink:BiologicalProcess regulation of protein homooligomerization Any process that modulates the frequency, rate or extent of protein homooligomerization. go-plus.json http://purl.obolibrary.org/obo/GO_0032462 GO:0032461 biolink:BiologicalProcess positive regulation of protein oligomerization Any process that activates or increases the frequency, rate or extent of protein oligomerization. go-plus.json up-regulation of protein oligomerization|upregulation of protein oligomerization|induction of protein oligomerization|up regulation of protein oligomerization|activation of protein oligomerization|stimulation of protein oligomerization http://purl.obolibrary.org/obo/GO_0032461 GO:0032460 biolink:BiologicalProcess negative regulation of protein oligomerization Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization. go-plus.json inhibition of protein oligomerization|down regulation of protein oligomerization|downregulation of protein oligomerization|down-regulation of protein oligomerization http://purl.obolibrary.org/obo/GO_0032460 GO:0032459 biolink:BiologicalProcess regulation of protein oligomerization Any process that modulates the frequency, rate or extent of protein oligomerization. go-plus.json http://purl.obolibrary.org/obo/GO_0032459 GO:0032458 biolink:BiologicalProcess slow endocytic recycling The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport. go-plus.json http://purl.obolibrary.org/obo/GO_0032458 GO:0032457 biolink:BiologicalProcess fast endocytic recycling The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport. go-plus.json direct endocytic recycling http://purl.obolibrary.org/obo/GO_0032457 GO:0007499 biolink:BiologicalProcess ectoderm and mesoderm interaction A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm. go-plus.json ectoderm/mesoderm interaction http://purl.obolibrary.org/obo/GO_0007499 GO:0007498 biolink:BiologicalProcess mesoderm development The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0007498 GO:0007497 biolink:BiologicalProcess posterior midgut development The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007497 GO:0007496 biolink:BiologicalProcess anterior midgut development The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007496 GO:0007495 biolink:BiologicalProcess visceral mesoderm-endoderm interaction involved in midgut development The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut. go-plus.json visceral mesoderm/endoderm interaction http://purl.obolibrary.org/obo/GO_0007495 GO:0007494 biolink:BiologicalProcess midgut development The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. go-plus.json http://purl.obolibrary.org/obo/GO_0007494 GO:0007493 biolink:BiologicalProcess endodermal cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json endoderm cell fate determination http://purl.obolibrary.org/obo/GO_0007493 CHEBI:79056 biolink:ChemicalSubstance plasticiser go-plus.json http://purl.obolibrary.org/obo/CHEBI_79056 CHEBI:79054 biolink:ChemicalSubstance D-arabinofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_79054 chebi_ph7_3 GO:0032456 biolink:BiologicalProcess endocytic recycling The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. go-plus.json retrograde transport, endosome to plasma membrane|retrograde transport of endocytic vesicles http://purl.obolibrary.org/obo/GO_0032456 CHEBI:137154 biolink:ChemicalSubstance (4Z,7Z,10Z,13Z,16Z,19R,20S)-19,20-epoxydocosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137154 GO:0032455 biolink:BiologicalProcess nerve growth factor processing The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor. go-plus.json NGF processing|beta-nerve growth factor processing http://purl.obolibrary.org/obo/GO_0032455 CHEBI:79059 biolink:ChemicalSubstance 2-arachidonoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79059 GO:0032454 biolink:MolecularActivity histone H3-methyl-lysine-9 demethylase activity Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein. Reactome:R-HSA-997263|Reactome:R-HSA-9011949|Reactome:R-HSA-9011985 go-plus.json histone demethylase activity (H3-K9 specific)|H3K49 demethylase activity http://purl.obolibrary.org/obo/GO_0032454 CHEBI:137152 biolink:ChemicalSubstance N-carbamoyl-D-methioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137152 chebi_ph7_3 CHEBI:79058 biolink:ChemicalSubstance D-arabinose 5-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79058 GO:0032453 biolink:MolecularActivity histone H3-methyl-lysine-4 demethylase activity Catalysis of the removal of a methyl group from a modified lysine residue at position 4 of the histone H3 protein. go-plus.json histone H3K4 demethylase activity|histone demethylase activity (H3-K4 specific) http://purl.obolibrary.org/obo/GO_0032453 CHEBI:79057 biolink:ChemicalSubstance hercynylcysteine sulfoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_79057 GO:0032452 biolink:MolecularActivity histone demethylase activity Catalysis of the removal of a methyl group from a histone. Reactome:R-HSA-5661123|Reactome:R-HSA-5661122|Reactome:R-HSA-4722133|Reactome:R-HSA-5625870|Reactome:R-HSA-4754187|Reactome:R-HSA-4754181|Reactome:R-HSA-5625848|Reactome:R-HSA-5661125|Reactome:R-HSA-5661124|Reactome:R-HSA-4724284|Reactome:R-HSA-5661116|Reactome:R-HSA-5661120|Reactome:R-HSA-4724279|Reactome:R-HSA-5423117|Reactome:R-HSA-4754176|Reactome:R-HSA-5625797|Reactome:R-HSA-3214912|Reactome:R-HSA-5661114|Reactome:R-HSA-5661121|Reactome:R-HSA-5661115 go-plus.json http://purl.obolibrary.org/obo/GO_0032452 GO:0032451 biolink:MolecularActivity demethylase activity Catalysis of the removal of a methyl group from a substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0032451 goslim_pir GO:0032450 biolink:MolecularActivity maltose alpha-glucosidase activity Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose. EC:3.2.1.20|MetaCyc:RXN-2141 go-plus.json maltase activity http://purl.obolibrary.org/obo/GO_0032450 CHEBI:137156 biolink:ChemicalSubstance phosphatidylserine(18:1/18:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137156 CHEBI:137155 biolink:ChemicalSubstance phosphatidylserine 36:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137155 GO:0032449 biolink:CellularComponent CBM complex A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation. go-plus.json CARMA1-BCL10-Malt1 complex http://purl.obolibrary.org/obo/GO_0032449 CHEBI:137172 biolink:ChemicalSubstance prostaglandin E2 2-glyceryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_137172 chebi_ph7_3 GO:0032448 biolink:MolecularActivity DNA hairpin binding Binding to a DNA region containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences. go-plus.json http://purl.obolibrary.org/obo/GO_0032448 GO:0032447 biolink:BiologicalProcess protein urmylation Covalent attachment of the ubiquitin-like protein URM1 to another protein. go-plus.json http://purl.obolibrary.org/obo/GO_0032447 GO:0032446 biolink:BiologicalProcess protein modification by small protein conjugation A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0032446 CHEBI:79070 biolink:ChemicalSubstance hercynylselenocysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79070 CHEBI:79063 biolink:ChemicalSubstance 4,4'-diapolycopenedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79063 chebi_ph7_3 CHEBI:79067 biolink:ChemicalSubstance 1-hexanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79067 CHEBI:79066 biolink:ChemicalSubstance 4-O-beta-D-glucosyl-trans-4-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79066 chebi_ph7_3 CHEBI:79065 biolink:ChemicalSubstance 4,4'-diaponeurosporenal go-plus.json http://purl.obolibrary.org/obo/CHEBI_79065 chebi_ph7_3 CHEBI:79064 biolink:ChemicalSubstance 4,4'-diaponeurosporenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79064 chebi_ph7_3 CHEBI:137165 biolink:ChemicalSubstance (S)-6-acetamido-3-aminohexanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137165 chebi_ph7_3 GO:0032445 biolink:BiologicalProcess fructose import The directed movement of the hexose monosaccharide fructose into a cell or organelle. go-plus.json fructose uptake http://purl.obolibrary.org/obo/GO_0032445 CHEBI:137164 biolink:ChemicalSubstance phosphatidic acid 36:3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137164 GO:0032444 biolink:CellularComponent activin responsive factor complex A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor. go-plus.json ARF complex http://purl.obolibrary.org/obo/GO_0032444 GO:0032443 biolink:BiologicalProcess regulation of ergosterol biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol. go-plus.json http://purl.obolibrary.org/obo/GO_0032443 GO:0032442 biolink:MolecularActivity phenylcoumaran benzylic ether reductase activity Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+. go-plus.json PCBER activity http://purl.obolibrary.org/obo/GO_0032442 CHEBI:79068 biolink:ChemicalSubstance crocin-1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_79068 chebi_ph7_3 GO:0032441 biolink:MolecularActivity pheophorbide a oxygenase activity Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O. EC:1.14.15.17|MetaCyc:RXN-7740|RHEA:48140 go-plus.json http://purl.obolibrary.org/obo/GO_0032441 CHEBI:137169 biolink:ChemicalSubstance alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137169 chebi_ph7_3 CHEBI:137168 biolink:ChemicalSubstance alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137168 chebi_ph7_3 GO:0032440 biolink:MolecularActivity 2-alkenal reductase [NAD(P)+] activity Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+. EC:1.3.1.74 go-plus.json n-alkanal:NAD(P)+ 2-oxidoreductase activity|NAD(P)H-dependent alkenal/one oxidoreductase activity http://purl.obolibrary.org/obo/GO_0032440 CHEBI:137167 biolink:ChemicalSubstance 16(S)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137167 chebi_ph7_3 CHEBI:137166 biolink:ChemicalSubstance 16(R)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137166 chebi_ph7_3 CHEBI:21650 biolink:ChemicalSubstance N-acyl-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21650 CHEBI:21652 biolink:ChemicalSubstance N-acyl-O-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21652 CHEBI:21655 biolink:ChemicalSubstance N-acylgalactosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21655 UBERON:0016481 biolink:AnatomicalEntity bronchial lymph node A lymph node that is part of a bronchus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016481 CHEBI:21654 biolink:ChemicalSubstance N-acyl-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21654 GO:0140346 biolink:MolecularActivity phosphatidylserine flippase activity Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json phosphatidylserine flippase activity (exoplasmic to cytosolic leaftlet) http://purl.obolibrary.org/obo/GO_0140346 GO:0140345 biolink:MolecularActivity phosphatidylcholine flippase activity Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json phosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet) http://purl.obolibrary.org/obo/GO_0140345 GO:0140348 biolink:MolecularActivity lysophosphatidylcholine flippase activity Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet) http://purl.obolibrary.org/obo/GO_0140348 GO:0140347 biolink:MolecularActivity N-retinylidene-phosphatidylethanolamine flippase activity Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json N-retinylidene-phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet) http://purl.obolibrary.org/obo/GO_0140347 GO:0140340 biolink:MolecularActivity cerebroside transfer activity Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location. go-plus.json cerebroside carrier activity http://purl.obolibrary.org/obo/GO_0140340 GO:0140341 biolink:MolecularActivity phosphatidylethanolamine floppase activity Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json phosphatidylethanolamine floppase activity (cytosolic to exoplasmic leaftlet) http://purl.obolibrary.org/obo/GO_0140341 GO:0140344 biolink:MolecularActivity triglyceride transfer activity Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location. go-plus.json triglyceride carrier activity http://purl.obolibrary.org/obo/GO_0140344 GO:0140343 biolink:MolecularActivity phosphatidylserine transfer activity Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane. go-plus.json intermembrane phosphatidylserine carrier activity http://purl.obolibrary.org/obo/GO_0140343 CHEBI:21656 biolink:ChemicalSubstance N-acyl-hexosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21656 CHEBI:21658 biolink:ChemicalSubstance N-acylglutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21658 CHEBI:21662 biolink:ChemicalSubstance N-acylneuraminic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21662 CHEBI:21663 biolink:ChemicalSubstance N-acylneuraminates go-plus.json http://purl.obolibrary.org/obo/CHEBI_21663 GO:0140334 biolink:BiologicalProcess lipopolysaccharide localization to cell outer membrane A process in which a lipopolysaccharide is transported to the cell outer membrane. go-plus.json LPS localization to cell outer membrane http://purl.obolibrary.org/obo/GO_0140334 GO:0140337 biolink:MolecularActivity diacylglyceride transfer activity Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location. go-plus.json diacylglyceride carrier activity http://purl.obolibrary.org/obo/GO_0140337 GO:0140339 biolink:MolecularActivity phosphatidylglycerol transfer activity Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location. go-plus.json phosphatidylglycerol carrier activity http://purl.obolibrary.org/obo/GO_0140339 GO:0140338 biolink:MolecularActivity sphingomyelin transfer activity Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane. go-plus.json sphingosine transmembrane transporter activity|sphingomyelin carrier activity http://purl.obolibrary.org/obo/GO_0140338 UBERON:0016479 biolink:AnatomicalEntity capsule of liver A collagenous capsule covering the external surface of the liver. go-plus.json glisson's capsule|fibrous capsule of liver|tunica fibrosa hepatis|tunica fibrosa (hepar)|liver capsule|fibrous capsule of Glisson|hepatic capsule|capsula fibrosa perivascularis http://purl.obolibrary.org/obo/UBERON_0016479 UBERON:0016478 biolink:AnatomicalEntity liver stroma A stroma that is part of a liver. go-plus.json hepatic stroma|stroma of liver http://purl.obolibrary.org/obo/UBERON_0016478 GO:0140331 biolink:BiologicalProcess aminophospholipid translocation The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. go-plus.json http://purl.obolibrary.org/obo/GO_0140331 GO:0140330 biolink:BiologicalProcess xenobiotic detoxification by transmembrane export across the cell outer membrane A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140330 CHEBI:45616 biolink:ChemicalSubstance (R)-1-phenylethanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_45616 chebi_ph7_3 GO:0140333 biolink:MolecularActivity glycerophospholipid flippase activity Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json glycerophospholipid flippase activity (exoplasmic to cytosolic leaftlet) http://purl.obolibrary.org/obo/GO_0140333 GO:0140332 biolink:MolecularActivity lipopolysaccharide transfer activity Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane. go-plus.json lipopolysaccharide carrier activity|intermembrane lipopolysaccharide transporter activity|intermembrane lipopolysaccharide transfer activity|intermembrane LPS transporter activity http://purl.obolibrary.org/obo/GO_0140332 CHEBI:21668 biolink:ChemicalSubstance N-alanyl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21668 GO:0140368 biolink:CellularComponent decoy receptor complex A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound. go-plus.json osteoclastogenesis inhibitory factor|osteoprotegerin complex http://purl.obolibrary.org/obo/GO_0140368 GO:0140367 biolink:BiologicalProcess antibacterial innate immune response An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0140367 GO:0140360 biolink:MolecularActivity cyclic-GMP-AMP transmembrane transporter activity Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0140360 GO:0140362 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140362 GO:0140361 biolink:BiologicalProcess cyclic-GMP-AMP transmembrane import across plasma membrane The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140361 GO:0140364 biolink:CellularComponent GW body A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs. go-plus.json GW-body http://purl.obolibrary.org/obo/GO_0140364 GO:0140363 biolink:CellularComponent TIS granule A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER). go-plus.json http://purl.obolibrary.org/obo/GO_0140363 GO:0140366 biolink:CellularComponent galectin lattice A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids. go-plus.json http://purl.obolibrary.org/obo/GO_0140366 GO:0140365 biolink:CellularComponent RNP body A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules. go-plus.json BR-body http://purl.obolibrary.org/obo/GO_0140365 CHEBI:21635 biolink:ChemicalSubstance N-acyl-D-glucosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21635 CHEBI:21637 biolink:ChemicalSubstance N-acyl-D-glucosamine phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21637 CHEBI:21638 biolink:ChemicalSubstance N-acylglucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21638 CHEBI:21644 biolink:ChemicalSubstance N-acyl-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21644 GO:0140357 biolink:BiologicalProcess heme export from vacuole to cytoplasm The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140357 UBERON:0016458 biolink:AnatomicalEntity esophageal hiatus A hole in the diaphragm through which the esophagus passes go-plus.json esophageal hiatus of diaphragm|oesophageal hiatus|oesophageal aperture http://purl.obolibrary.org/obo/UBERON_0016458 GO:0140359 biolink:MolecularActivity ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. Reactome:R-HSA-5362459|Reactome:R-HSA-5387389|Reactome:R-HSA-9661405|Reactome:R-HSA-5683325|Reactome:R-HSA-5223313|Wikipedia:ATP-binding_cassette_transporter|TC:3.A.1|Reactome:R-HSA-266070 go-plus.json ABC transporter|ABC-type efflux permease activity|ATP binding cassette transporter|ABC-type uptake permease activity|ABC-type efflux porter activity|ATP-binding cassette (ABC) transporter activity|ATP-binding cassette transporter|ABC-type transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140359 GO:0140358 biolink:MolecularActivity P-type transmembrane transporter activity Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and inorganic phosphate (Pi), the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol. TC:3.A.3|Wikipedia:P-type_ATPase go-plus.json P-type ATPase|E1-E2 ATPase http://purl.obolibrary.org/obo/GO_0140358 GO:0140351 biolink:MolecularActivity glycosylceramide flippase activity Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar. go-plus.json glycoceramide flippase activity|galactosylceramide flippase activity|glycosylceramide flippase activity (exoplasmic to cytosolic leaftlet)|glucosylceramide flippase activity|galactocerebroside flippase activity http://purl.obolibrary.org/obo/GO_0140351 GO:0140353 biolink:BiologicalProcess lipid export from cell The directed movement of a lipid from a cell, into the extracellular region. go-plus.json lipid efflux http://purl.obolibrary.org/obo/GO_0140353 GO:0140352 biolink:BiologicalProcess export from cell The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. go-plus.json efflux http://purl.obolibrary.org/obo/GO_0140352 GO:0140355 biolink:MolecularActivity cargo receptor ligand activity The activity of a gene product that interacts with a cargo receptor and initiates endocytosis. go-plus.json cargo http://purl.obolibrary.org/obo/GO_0140355 GO:0140354 biolink:BiologicalProcess lipid import into cell The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. go-plus.json lipid uptake http://purl.obolibrary.org/obo/GO_0140354 CHEBI:21645 biolink:ChemicalSubstance N-acyl-L-arginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21645 CHEBI:21647 biolink:ChemicalSubstance N-acyl-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21647 GO:0140302 biolink:BiologicalProcess pollen-style interaction The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte. go-plus.json http://purl.obolibrary.org/obo/GO_0140302 GO:0140301 biolink:BiologicalProcess pollen-stigma interaction The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae. go-plus.json http://purl.obolibrary.org/obo/GO_0140301 GO:0140303 biolink:MolecularActivity intramembrane lipid transporter activity Enables the transport of a lipid from a region of a membrane to a different region on the same membrane. go-plus.json translocase activity|flippase activity http://purl.obolibrary.org/obo/GO_0140303 GO:0140306 biolink:MolecularActivity lipoprotein releasing activity The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140306 NCBITaxon:56615 biolink:OrganismalEntity Puccinia graminis f. sp. tritici go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_56615 GO:0140300 biolink:BiologicalProcess serine import into mitochondrion The process in which serine is transported from the cytosol into the mitochondrial matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0140300 CHEBI:21615 biolink:ChemicalSubstance N-acetyl-D-muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21615 UBERON:6007280 biolink:AnatomicalEntity insect embryonic/larval head sense organ Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730). go-plus.json larval head sense organ http://purl.obolibrary.org/obo/UBERON_6007280 CHEBI:21619 biolink:ChemicalSubstance N-acetylneuraminates go-plus.json http://purl.obolibrary.org/obo/CHEBI_21619 CHEBI:21622 biolink:ChemicalSubstance N-acetylneuraminic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_21622 CHEBI:3638 biolink:ChemicalSubstance chloroquine go-plus.json http://purl.obolibrary.org/obo/CHEBI_3638 CHEBI:21626 biolink:ChemicalSubstance N-acetylphenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21626 GO:0140323 biolink:MolecularActivity solute:anion antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(in) + solute(out) = anion(out) + solute(in). go-plus.json http://purl.obolibrary.org/obo/GO_0140323 GO:0140326 biolink:MolecularActivity ATPase-coupled intramembrane lipid transporter activity Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases. EC:7.6.2.1|Reactome:R-HSA-939763|Reactome:R-HSA-947591|MetaCyc:3.6.3.1-RXN go-plus.json ATPase-dependent phospholipid transporter activity|phospholipid translocating ATPase activity|aminophospholipid-transporting ATPase|phospholipid flippase activity|phospholipid-translocating ATPase activity|phospholipid-transporting ATPase activity|ATPase-coupled phospholipid transporter activity http://purl.obolibrary.org/obo/GO_0140326 GO:0140325 biolink:BiologicalProcess negative regulation of protein localization to medial cortex Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex. go-plus.json http://purl.obolibrary.org/obo/GO_0140325 GO:0140328 biolink:MolecularActivity floppase activity Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json floppase activity (cytosolic to exoplasmic leaftlet) http://purl.obolibrary.org/obo/GO_0140328 GO:0140327 biolink:MolecularActivity flippase activity Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json flippase activity (exoplasmic to cytosolic leaftlet) http://purl.obolibrary.org/obo/GO_0140327 GO:0140329 biolink:BiologicalProcess lysophospholipid translocation The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. go-plus.json http://purl.obolibrary.org/obo/GO_0140329 GO:0140320 biolink:MolecularActivity PAMP receptor decoy activity A gene product which recognizes, binds and sequesters PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response. go-plus.json pathogen-associated molecular pattern receptor decoy activity|pattern recognition receptor decoy activity http://purl.obolibrary.org/obo/GO_0140320 GO:0140321 biolink:BiologicalProcess negative regulation by symbiont of host autophagy Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0140321 UBERON:0016490 biolink:AnatomicalEntity auditory system is the sensory system for the sense of hearing. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016490 OBO:chebi#is_enantiomer_of biolink:OntologyClass is enantiomer of go-plus.json http://purl.obolibrary.org/obo/chebi#is_enantiomer_of GO:0140313 biolink:MolecularActivity molecular sequestering activity The selective interaction of a protein with a specific molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140313 GO:0140312 biolink:MolecularActivity cargo adaptor activity Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery. go-plus.json endocytic adaptor activity http://purl.obolibrary.org/obo/GO_0140312 GO:0140315 biolink:MolecularActivity iron ion sequestering activity The selective interaction of a protein with an iron ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140315 GO:0140314 biolink:MolecularActivity calcium ion sequestering activity The selective interaction of a protein with a calcium ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140314 GO:0140317 biolink:BiologicalProcess export across cell outer membrane The directed movement of a substance across the outer membrane in cells with two membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0140317 GO:0140316 biolink:MolecularActivity obsolete vesicular transport adaptor activity OBSOLETE. Binding directly to sorting signals in the cytosolic tails of transmembrane cargos (or transmembrane cargo receptors serving as recognition interfaces for lumenal cargos), to concentrate them into vesicles or tubules for transport via intracellular vesicular transport or the secretory pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0140316 GO:0140319 biolink:MolecularActivity receptor decoy activity Recognizing, binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor. go-plus.json decoy death receptor activity|decoy receptor http://purl.obolibrary.org/obo/GO_0140319 GO:0140318 biolink:MolecularActivity protein transporter activity Directly binding to a specific protein and delivering it to a specific cellular location. Reactome:R-HSA-9662818|Reactome:R-HSA-9662747 go-plus.json protein carrier activity|protein transport chaperone http://purl.obolibrary.org/obo/GO_0140318 GO:0140311 biolink:MolecularActivity protein sequestering activity The selective interaction of a protein with a specific protein, to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140311 CHEBI:21601 biolink:ChemicalSubstance N-acetyl-D-hexosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21601 chebi_ph7_3 UBERON:0016405 biolink:AnatomicalEntity pulmonary capillary A capillary that is part of a lung. go-plus.json capillary of lung http://purl.obolibrary.org/obo/UBERON_0016405 UBERON:0016400 biolink:AnatomicalEntity infrapatellar fat pad The infrapatellar fat pad, also known as Hoffa's fat pad, is a cylindrical piece of fat that is situated under and behind the patella bone within the knee. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016400 CHEBI:3663 biolink:ChemicalSubstance cholesteryl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_3663 chebi_ph7_3 CHEBI:31059 biolink:ChemicalSubstance 13-dihydrodaunorubicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31059 CHEBI:31058 biolink:ChemicalSubstance (13R)-13-dihydrocarminomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31058 CHEBI:31057 biolink:ChemicalSubstance 13-deoxydaunorubicin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31057 CHEBI:31056 biolink:ChemicalSubstance 13-deoxycarminomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31056 GO:0071990 biolink:BiologicalProcess maintenance of protein location to spindle pole body Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere. go-plus.json maintenance of protein location at spindle pole body|maintenance of protein location in spindle pole body http://purl.obolibrary.org/obo/GO_0071990 GO:0007409 biolink:BiologicalProcess axonogenesis De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells. go-plus.json axon growth|axon morphogenesis|neuron long process generation http://purl.obolibrary.org/obo/GO_0007409 GO:0007408 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007408 GO:0007407 biolink:BiologicalProcess neuroblast activation A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. go-plus.json http://purl.obolibrary.org/obo/GO_0007407 GO:0007406 biolink:BiologicalProcess negative regulation of neuroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. go-plus.json down-regulation of neuroblast proliferation|suppression of neuroblast proliferation|downregulation of neuroblast proliferation|down regulation of neuroblast proliferation|inhibition of neuroblast proliferation http://purl.obolibrary.org/obo/GO_0007406 GO:0007405 biolink:BiologicalProcess neuroblast proliferation The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0007405 GO:0007404 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007404 GO:0007403 biolink:BiologicalProcess glial cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0007403 GO:0007402 biolink:BiologicalProcess ganglion mother cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0007402 GO:0007401 biolink:BiologicalProcess obsolete pan-neural process OBSOLETE. (Was not defined before being made obsolete). go-plus.json pan-neural process http://purl.obolibrary.org/obo/GO_0007401 GO:0007400 biolink:BiologicalProcess neuroblast fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus. go-plus.json neuroblast identity determination|neuroblast cell fate determination http://purl.obolibrary.org/obo/GO_0007400 CHEBI:45696 biolink:ChemicalSubstance hydrogensulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_45696 NCBITaxon:980083 biolink:OrganismalEntity Camelineae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_980083 GO:0071999 biolink:BiologicalProcess extracellular polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures. go-plus.json extracellular polysaccharide breakdown|extracellular polysaccharide catabolism|extracellular polysaccharide degradation http://purl.obolibrary.org/obo/GO_0071999 GO:0071998 biolink:BiologicalProcess ascospore release from ascus A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive. go-plus.json ascospore liberation http://purl.obolibrary.org/obo/GO_0071998 GO:0071997 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071997 GO:0071996 biolink:BiologicalProcess glutathione transmembrane import into vacuole The directed movement of glutathione into the vacuole across the vacuolar membrane. go-plus.json glutathione transport into vacuole http://purl.obolibrary.org/obo/GO_0071996 CHEBI:31069 biolink:ChemicalSubstance 2,3,5-trichloro-cis,cis-muconic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31069 GO:0071995 biolink:BiologicalProcess phytochelatin import into vacuole The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. go-plus.json cadystin import into vacuole|phytochelatin transport into vacuole http://purl.obolibrary.org/obo/GO_0071995 GO:0071994 biolink:BiologicalProcess phytochelatin transmembrane transport The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. go-plus.json cadystin transmembrane transport|phytochelatin membrane transport http://purl.obolibrary.org/obo/GO_0071994 GO:0071993 biolink:BiologicalProcess phytochelatin transport The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. go-plus.json cadystin transport http://purl.obolibrary.org/obo/GO_0071993 GO:0071992 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071992 GO:0071991 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071991 NCBITaxon:8457 biolink:OrganismalEntity Sauropsida go-plus.json sauropsids http://purl.obolibrary.org/obo/NCBITaxon_8457 CHEBI:31047 biolink:ChemicalSubstance 10-carboxy-13-deoxycarminomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31047 UBERON:0016442 biolink:AnatomicalEntity median palatine suture the line of junction between the horizontal parts of the palatine bones that extends from both sides of the skull to form the posterior part of the hard palate. go-plus.json midpalatal suture of skull|median palatine suture of skull|middle palatine suture of skull http://purl.obolibrary.org/obo/UBERON_0016442 CHEBI:21698 biolink:ChemicalSubstance N-cysteinyl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21698 UBERON:0016447 biolink:AnatomicalEntity hair of trunk A strand of hair that is part of a trunk. go-plus.json trunk hair http://purl.obolibrary.org/obo/UBERON_0016447 UBERON:0016446 biolink:AnatomicalEntity hair of head A strand of hair that is part of a head. go-plus.json hair of scalp|head hair http://purl.obolibrary.org/obo/UBERON_0016446 GO:0140382 biolink:MolecularActivity tryptamine 4-monooxygenase activity Catalysis of the reaction: tryptamine + reduced acceptor + O(2) <=> 4-hydroxytryptamine + acceptor + H(2)O. RHEA:15865|EC:1.14.99.59 go-plus.json http://purl.obolibrary.org/obo/GO_0140382 GO:0140381 biolink:MolecularActivity 4-hydroxytryptamine 4-phosphate methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin. RHEA:55568|EC:2.1.1.345 go-plus.json norbaeocystin methyltransferase|psilocybin synthase http://purl.obolibrary.org/obo/GO_0140381 GO:0140384 biolink:BiologicalProcess metacyclogenesis The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania. go-plus.json http://purl.obolibrary.org/obo/GO_0140384 GO:0140383 biolink:MolecularActivity 4-hydroxytryptamine kinase activity Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H(+). RHEA:55564|EC:2.7.1.222 go-plus.json http://purl.obolibrary.org/obo/GO_0140383 CHEBI:31014 biolink:ChemicalSubstance tetracosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31014 chebi_ph7_3 CHEBI:31013 biolink:ChemicalSubstance cerotate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31013 chebi_ph7_3 CHEBI:31011 biolink:ChemicalSubstance valerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31011 chebi_ph7_3 GO:0140380 biolink:BiologicalProcess psilocybin biosynthetic process The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product. go-plus.json http://purl.obolibrary.org/obo/GO_0140380 UBERON:0016435 biolink:AnatomicalEntity chest wall Subdivision of thorax which includes all structures from the skin to the costal pleura. Examples: There is only one chest wall. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016435 GO:0140373 biolink:BiologicalProcess histone H3-K14 ubiquitination The modification of histone H3 by the addition of one or more ubiquitin groups to a lysine residue at position 14 of the histone. go-plus.json histone H3-K14 ubiquitylation|histone H3 ubiquitination at K14|histone H3K14 ubiquitination http://purl.obolibrary.org/obo/GO_0140373 GO:0140372 biolink:BiologicalProcess histone H3 ubiquitination The modification of histone H3 by the addition of one or more ubiquitin groups. go-plus.json histone H3 ubiquitylation http://purl.obolibrary.org/obo/GO_0140372 GO:0140375 biolink:MolecularActivity immune receptor activity Receiving a signal and transmitting it in a cell to initiate an immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0140375 GO:0140374 biolink:BiologicalProcess antiviral innate immune response A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0140374 GO:0140376 biolink:MolecularActivity innate immune receptor activity Receiving a signal and transmitting it in a cell to initiate an innate immune response. go-plus.json http://purl.obolibrary.org/obo/GO_0140376 CHEBI:583099 biolink:ChemicalSubstance ent-zingiberene go-plus.json http://purl.obolibrary.org/obo/CHEBI_583099 chebi_ph7_3 CHEBI:21672 biolink:ChemicalSubstance N-amidino-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21672 CHEBI:21675 biolink:ChemicalSubstance N-asparaginyl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21675 CHEBI:21676 biolink:ChemicalSubstance N-aspartyl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21676 CHEBI:21681 biolink:ChemicalSubstance N-benzoyl-D-arginines go-plus.json http://purl.obolibrary.org/obo/CHEBI_21681 CHEBI:31009 biolink:ChemicalSubstance hexacosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31009 CHEBI:21686 biolink:ChemicalSubstance N-carbamoyl-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21686 UBERON:0016410 biolink:AnatomicalEntity male breast A breast that is part of a male organism. go-plus.json mamma masculina http://purl.obolibrary.org/obo/UBERON_0016410 CHEBI:45630 biolink:ChemicalSubstance 4-oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45630 GO:0140393 biolink:MolecularActivity norsolorinic acid ketoreductase activity Catalysis of the reaction: (1'S)-averantin + NADP(+) <=> norsolorinic acid + NADPH. MetaCyc:RXN-9480|EC:1.1.1.349|KEGG_REACTION:R10309|RHEA:35447 go-plus.json http://purl.obolibrary.org/obo/GO_0140393 NCBITaxon:8492 biolink:OrganismalEntity Archosauria go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_8492 GO:0140395 biolink:MolecularActivity averantin hydroxylase activity Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O(2) <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H(2)O. Involved in aflatoxin biosynthesis. MetaCyc:RXN-9482|RHEA:35575|EC:1.14.14.116 go-plus.json http://purl.obolibrary.org/obo/GO_0140395 GO:0140394 biolink:MolecularActivity ABC-type azole transporter activity Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out). RHEA:33503 go-plus.json azole ABC transporter activity|ATPase-coupled azole transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140394 GO:0140397 biolink:MolecularActivity versiconal hemiacetal acetate esterase activity Catalyzes the reactions: versiconal hemiacetal acetate + H(2)O <=> versiconal + acetate, as well as versiconol acetate + H(2)O <=> versiconol + acetate. EC:3.1.1.94|MetaCyc:RXN-9493|MetaCyc:RXN-9488|RHEA:35715 go-plus.json http://purl.obolibrary.org/obo/GO_0140397 GO:0140396 biolink:MolecularActivity 5'-hydroxyaverantin dehydrogenase activity Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH. RHEA:35475|EC:1.1.1.352 go-plus.json http://purl.obolibrary.org/obo/GO_0140396 GO:0140399 biolink:MolecularActivity aflatoxin B synthase activity Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O(2) <=> aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H(2)O + methanol + CO(2). Produces both aflatoxin B(1) and aflatoxin B(2). EC:1.14.14.117|MetaCyc:RXN-9502|RHEA:35759|MetaCyc:RXN-9497 go-plus.json http://purl.obolibrary.org/obo/GO_0140399 GO:0140398 biolink:MolecularActivity versicolorin B desaturase activity Catalyzes the reaction: versicolorin B + NADPH + O(2) <=> versicolorin A + NADP(+) + 2 H(2)O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus. MetaCyc:RXN-9495|RHEA:35743|KEGG_REACTION:R10479 go-plus.json http://purl.obolibrary.org/obo/GO_0140398 CHEBI:31004 biolink:ChemicalSubstance triacontanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31004 chebi_ph7_3 CHEBI:21689 biolink:ChemicalSubstance N-carbamoyl-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21689 CHEBI:31003 biolink:ChemicalSubstance triacontanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31003 CHEBI:31002 biolink:ChemicalSubstance octacosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31002 chebi_ph7_3 CHEBI:31001 biolink:ChemicalSubstance octacosanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31001 GO:0032559 biolink:MolecularActivity adenyl ribonucleotide binding Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032559 CHEBI:137260 biolink:ChemicalSubstance omega-[(methylsulfinyl)alkyl]glucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137260 GO:0032558 biolink:MolecularActivity adenyl deoxyribonucleotide binding Binding to an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032558 GO:0032557 biolink:MolecularActivity pyrimidine ribonucleotide binding Binding to a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032557 GO:0032556 biolink:MolecularActivity pyrimidine deoxyribonucleotide binding Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032556 GO:0007599 biolink:BiologicalProcess hemostasis The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. Wikipedia:Hemostasis go-plus.json http://purl.obolibrary.org/obo/GO_0007599 GO:0007598 biolink:BiologicalProcess blood coagulation, extrinsic pathway A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X. go-plus.json http://purl.obolibrary.org/obo/GO_0007598 GO:0007597 biolink:BiologicalProcess blood coagulation, intrinsic pathway A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X. go-plus.json http://purl.obolibrary.org/obo/GO_0007597 GO:0007596 biolink:BiologicalProcess blood coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. Wikipedia:Coagulation go-plus.json blood clotting http://purl.obolibrary.org/obo/GO_0007596 GO:0007595 biolink:BiologicalProcess lactation The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. Wikipedia:Lactation go-plus.json milk secretion http://purl.obolibrary.org/obo/GO_0007595 GO:0007594 biolink:BiologicalProcess puparial adhesion The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation. go-plus.json puparial glue http://purl.obolibrary.org/obo/GO_0007594 GO:0007593 biolink:BiologicalProcess chitin-based cuticle sclerotization The process of hardening of a chitin-based cuticle. go-plus.json chitin-based cuticle tanning|cuticle hardening http://purl.obolibrary.org/obo/GO_0007593 GO:0007592 biolink:BiologicalProcess obsolete protein-based cuticle development OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans. go-plus.json protein-based cuticle development|protein-based cuticle anabolism|protein-based cuticle synthesis|protein-based cuticle formation|protein-based cuticle biosynthetic process http://purl.obolibrary.org/obo/GO_0007592 GO:0032555 biolink:MolecularActivity purine ribonucleotide binding Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032555 GO:0032554 biolink:MolecularActivity purine deoxyribonucleotide binding Binding to a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032554 GO:0032553 biolink:MolecularActivity ribonucleotide binding Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032553 GO:0032552 biolink:MolecularActivity deoxyribonucleotide binding Binding to a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032552 GO:0032551 biolink:MolecularActivity pyrimidine ribonucleoside binding Binding to a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose. go-plus.json http://purl.obolibrary.org/obo/GO_0032551 CHEBI:137257 biolink:ChemicalSubstance omega-[(methylsulfanyl)alkyl]glucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137257 GO:0032550 biolink:MolecularActivity purine ribonucleoside binding Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose. go-plus.json http://purl.obolibrary.org/obo/GO_0032550 GO:0032549 biolink:MolecularActivity ribonucleoside binding Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose. go-plus.json http://purl.obolibrary.org/obo/GO_0032549 GO:0032548 biolink:MolecularActivity pyrimidine deoxyribonucleoside binding Binding to a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0032548 GO:0032547 biolink:MolecularActivity purine deoxyribonucleoside binding Binding to a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0032547 GO:0032546 biolink:MolecularActivity deoxyribonucleoside binding Binding to a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose. go-plus.json http://purl.obolibrary.org/obo/GO_0032546 GO:0032545 biolink:CellularComponent CURI complex A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p. go-plus.json http://purl.obolibrary.org/obo/GO_0032545 CHEBI:137269 biolink:ChemicalSubstance (5Z,8Z,11Z,17Z)-14,15-epoxyicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137269 GO:0032544 biolink:BiologicalProcess plastid translation The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. go-plus.json plastid protein synthesis|plastid protein translation|plastid protein formation|plastid protein biosynthesis|plastid protein anabolism http://purl.obolibrary.org/obo/GO_0032544 GO:0032543 biolink:BiologicalProcess mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. go-plus.json mitochondrial protein anabolism|mitochondrial protein synthesis|mitochondrial protein formation|mitochondrial protein translation|mitochondrial protein biosynthesis http://purl.obolibrary.org/obo/GO_0032543 goslim_yeast|goslim_drosophila GO:0032542 biolink:MolecularActivity sulfiredoxin activity Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R. EC:1.8.98.2|RHEA:17545|MetaCyc:1.8.98.2-RXN go-plus.json sulphiredoxin activity|peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]|Srx1|peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity http://purl.obolibrary.org/obo/GO_0032542 GO:0032541 biolink:CellularComponent cortical endoplasmic reticulum A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. go-plus.json peripheral ER|peripheral endoplasmic reticulum|ER-PM peripheral junction|cortical ER http://purl.obolibrary.org/obo/GO_0032541 GO:0032540 biolink:BiologicalProcess positive regulation of host-seeking behavior Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism. go-plus.json up regulation of host-seeking behavior|activation of host-seeking behavior|stimulation of host-seeking behavior|up-regulation of host-seeking behavior|upregulation of host-seeking behavior|positive regulation of host-seeking behaviour http://purl.obolibrary.org/obo/GO_0032540 CHEBI:137267 biolink:ChemicalSubstance (5Z,8Z,14Z,17Z)-11,12-epoxyicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137267 CHEBI:137265 biolink:ChemicalSubstance (E)-1-(glutathion-S-yl)-2-(indol-3-yl)acetohydroximate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137265 GO:0032539 biolink:BiologicalProcess negative regulation of host-seeking behavior Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism. go-plus.json inhibition of host-seeking behavior|negative regulation of host-seeking behaviour|down regulation of host-seeking behavior|downregulation of host-seeking behavior|down-regulation of host-seeking behavior http://purl.obolibrary.org/obo/GO_0032539 GO:0032538 biolink:BiologicalProcess regulation of host-seeking behavior Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism. go-plus.json regulation of host-seeking behaviour http://purl.obolibrary.org/obo/GO_0032538 GO:0032537 biolink:BiologicalProcess host-seeking behavior The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host. go-plus.json host-seeking behaviour http://purl.obolibrary.org/obo/GO_0032537 GO:0032536 biolink:BiologicalProcess regulation of cell projection size A process that modulates the size of a cell projection. go-plus.json http://purl.obolibrary.org/obo/GO_0032536 GO:0007579 biolink:BiologicalProcess obsolete senescence factor accumulation OBSOLETE. (Was not defined before being made obsolete). go-plus.json senescence factor accumulation http://purl.obolibrary.org/obo/GO_0007579 GO:0032535 biolink:BiologicalProcess regulation of cellular component size A process that modulates the size of a cellular component. go-plus.json http://purl.obolibrary.org/obo/GO_0032535 GO:0032534 biolink:BiologicalProcess regulation of microvillus assembly A process that modulates the formation of a microvillus. go-plus.json regulation of microvillus biogenesis http://purl.obolibrary.org/obo/GO_0032534 GO:0007578 biolink:BiologicalProcess obsolete aging dependent sterility (sensu Saccharomyces) OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes. go-plus.json aging dependent sterility (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007578 GO:0007577 biolink:BiologicalProcess obsolete autophagic death (sensu Saccharomyces) OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA. go-plus.json autophagic death (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007577 GO:0007576 biolink:BiologicalProcess nucleolar fragmentation The cell aging process that results in the nucleolus breaking down into fragments. go-plus.json nucleolar size increase http://purl.obolibrary.org/obo/GO_0007576 GO:0007575 biolink:BiologicalProcess obsolete nucleolar size increase OBSOLETE. The process of nucleolar expansion. go-plus.json nucleolar size increase http://purl.obolibrary.org/obo/GO_0007575 GO:0007574 biolink:BiologicalProcess obsolete cell aging (sensu Saccharomyces) OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell. go-plus.json cell aging (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007574 GO:0007573 biolink:BiologicalProcess obsolete age dependent increased protein content OBSOLETE. (Was not defined before being made obsolete). go-plus.json age dependent increased protein content http://purl.obolibrary.org/obo/GO_0007573 GO:0007572 biolink:BiologicalProcess obsolete age dependent decreased translational activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json age dependent decreased translational activity http://purl.obolibrary.org/obo/GO_0007572 GO:0007571 biolink:BiologicalProcess age-dependent general metabolic decline A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis. go-plus.json age-dependent yeast cell size increase|age-dependent increased protein content|nucleolar size increase|age-dependent decreased translational activity http://purl.obolibrary.org/obo/GO_0007571 GO:0007570 biolink:BiologicalProcess obsolete age dependent accumulation of genetic damage OBSOLETE. (Was not defined before being made obsolete). go-plus.json age dependent accumulation of genetic damage http://purl.obolibrary.org/obo/GO_0007570 GO:0007580 biolink:BiologicalProcess extrachromosomal circular DNA accumulation involved in cell aging Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication. go-plus.json extrachromosomal circular DNA accumulation during cell ageing|extrachromosomal circular DNA accumulation during cell aging http://purl.obolibrary.org/obo/GO_0007580 CHEBI:162247 biolink:ChemicalSubstance 2-cis,6-trans-farnesyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_162247 chebi_ph7_3 GO:0032533 biolink:BiologicalProcess regulation of follicle cell microvillus length A process that modulates the length of a microvillus on a follicle cell. go-plus.json http://purl.obolibrary.org/obo/GO_0032533 GO:0032532 biolink:BiologicalProcess regulation of microvillus length A process that modulates the length of a microvillus. go-plus.json http://purl.obolibrary.org/obo/GO_0032532 NCBITaxon:2605435 biolink:OrganismalEntity Evosea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2605435 GO:0032531 biolink:BiologicalProcess regulation of follicle cell microvillus organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. go-plus.json regulation of follicle cell microvillus organization and biogenesis|regulation of follicle cell microvillus organisation http://purl.obolibrary.org/obo/GO_0032531 GO:0032530 biolink:BiologicalProcess regulation of microvillus organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. go-plus.json regulation of microvillus organisation|regulation of microvillus organization and biogenesis http://purl.obolibrary.org/obo/GO_0032530 NCBITaxon:8287 biolink:OrganismalEntity Sarcopterygii go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_8287 GO:0032529 biolink:BiologicalProcess follicle cell microvillus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments. go-plus.json follicle cell microvillus organisation|follicle cell microvillus organization and biogenesis http://purl.obolibrary.org/obo/GO_0032529 GO:0032528 biolink:BiologicalProcess microvillus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. go-plus.json microvillus organization and biogenesis|microvillus organisation http://purl.obolibrary.org/obo/GO_0032528 GO:0032527 biolink:BiologicalProcess protein exit from endoplasmic reticulum The directed movement of proteins from the endoplasmic reticulum. go-plus.json protein export from ER|protein export from endoplasmic reticulum|protein exit from ER http://purl.obolibrary.org/obo/GO_0032527 GO:0032526 biolink:BiologicalProcess response to retinoic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. go-plus.json response to vitamin A acid http://purl.obolibrary.org/obo/GO_0032526 GO:0032525 biolink:BiologicalProcess somite rostral/caudal axis specification The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary. go-plus.json somite rostrocaudal axis specification|somite rostrocaudal polarity http://purl.obolibrary.org/obo/GO_0032525 GO:0032524 biolink:BiologicalProcess obsolete nutrient export OBSOLETE. The directed movement of nutrients out of a cell or organelle. go-plus.json nutrient export http://purl.obolibrary.org/obo/GO_0032524 GO:0032523 biolink:MolecularActivity silicon efflux transmembrane transporter activity Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane. go-plus.json silicon efflux transporter activity http://purl.obolibrary.org/obo/GO_0032523 GO:0007589 biolink:BiologicalProcess body fluid secretion The controlled release of a fluid by a cell or tissue in an animal. go-plus.json http://purl.obolibrary.org/obo/GO_0007589 GO:0007588 biolink:BiologicalProcess excretion The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. Wikipedia:Excretion go-plus.json http://purl.obolibrary.org/obo/GO_0007588 goslim_pir GO:0007587 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007587 GO:0007586 biolink:BiologicalProcess digestion The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. Wikipedia:Digestion go-plus.json http://purl.obolibrary.org/obo/GO_0007586 goslim_pir|goslim_chembl GO:0007585 biolink:BiologicalProcess respiratory gaseous exchange by respiratory system The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. go-plus.json breathing|respiration http://purl.obolibrary.org/obo/GO_0007585 goslim_chembl GO:0007584 biolink:BiologicalProcess response to nutrient Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. go-plus.json response to nutrients|nutritional response pathway http://purl.obolibrary.org/obo/GO_0007584 GO:0007583 biolink:BiologicalProcess obsolete killer activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json killer activity http://purl.obolibrary.org/obo/GO_0007583 GO:0007582 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007582 GO:0007581 biolink:BiologicalProcess obsolete age-dependent yeast cell size increase OBSOLETE. (Was not defined before being made obsolete). go-plus.json age-dependent yeast cell size increase http://purl.obolibrary.org/obo/GO_0007581 GO:0007591 biolink:BiologicalProcess molting cycle, chitin-based cuticle The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster. go-plus.json chitin-based cuticle molting cycle http://purl.obolibrary.org/obo/GO_0007591 GO:0007590 biolink:BiologicalProcess obsolete fat body metabolic process (sensu Insecta) OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557). go-plus.json fat body metabolic process (sensu Insecta) http://purl.obolibrary.org/obo/GO_0007590 PR:000006267 biolink:Protein dystroglycan A protein that is a translation product of the human DAG1 gene or a 1:1 ortholog thereof. go-plus.json dystrophin-associated glycoprotein 1|Dag-1|DAG1 http://purl.obolibrary.org/obo/PR_000006267 NCBITaxon:8292 biolink:OrganismalEntity Amphibia go-plus.json amphibians|amphibians http://purl.obolibrary.org/obo/NCBITaxon_8292 GO:0032522 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032522 CHEBI:176894 biolink:ChemicalSubstance vitamin B6 phosphate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_176894 GO:0032521 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032521 GO:0032520 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032520 GO:0032519 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032519 GO:0032518 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032518 GO:0032517 biolink:CellularComponent SOD1-calcineurin complex A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1. go-plus.json http://purl.obolibrary.org/obo/GO_0032517 GO:0032516 biolink:BiologicalProcess positive regulation of phosphoprotein phosphatase activity Any process that activates or increases the activity of a phosphoprotein phosphatase. go-plus.json activation of protein phosphatase type 2B activity|calcineurin activation|upregulation of phosphoprotein phosphatase activity|up-regulation of protein phosphatase 2 activity|positive regulation of protein phosphatase type 2A activity|stimulation of protein phosphatase 2 activity|positive regulation of protein phosphatase type 2B activity|up regulation of protein phosphatase type 2A activity|up regulation of protein phosphatase type 2B activity|activation of calcineurin activity|activation of protein phosphatase 3 activity|up regulation of phosphoprotein phosphatase activity|positive regulation of calcineurin activity|activation of phosphoprotein phosphatase activity|positive regulation of protein phosphatase 2 activity|positive regulation of protein phosphatase 3 activity|up regulation of protein phosphatase 2 activity|up regulation of calcineurin activity|up regulation of protein phosphatase 3 activity|stimulation of phosphoprotein phosphatase activity|upregulation of protein phosphatase type 2A activity|upregulation of protein phosphatase type 2B activity|upregulation of protein phosphatase 2 activity|up-regulation of phosphoprotein phosphatase activity|up-regulation of protein phosphatase type 2A activity|up-regulation of protein phosphatase type 2B activity|stimulation of protein phosphatase type 2A activity|stimulation of protein phosphatase type 2B activity|activation of protein phosphatase type 2A activity http://purl.obolibrary.org/obo/GO_0032516 GO:0032515 biolink:BiologicalProcess negative regulation of phosphoprotein phosphatase activity Any process that stops or reduces the activity of a phosphoprotein phosphatase. go-plus.json down-regulation of protein phosphatase type 2A activity|negative regulation of protein phosphatase type 2A activity|negative regulation of protein phosphatase type 2B activity|down-regulation of protein phosphatase type 2B activity|down regulation of phosphoprotein phosphatase activity|downregulation of phosphoprotein phosphatase activity|negative regulation of protein phosphatase 2 activity|downregulation of protein phosphatase type 2A activity|negative regulation of calcineurin activity|downregulation of protein phosphatase type 2B activity|down regulation of protein phosphatase type 2A activity|down regulation of protein phosphatase type 2B activity|down-regulation of phosphoprotein phosphatase activity|downregulation of protein phosphatase 2 activity|downregulation of protein phosphatase 3 activity|downregulation of calcineurin activity|inhibition of protein phosphatase type 2A activity|regulation of protein phosphatase 3 activity|inhibition of protein phosphatase type 2B activity|down regulation of protein phosphatase 2 activity|down regulation of protein phosphatase 3 activity|down regulation of calcineurin activity|inhibition of phosphoprotein phosphatase activity|inhibition of protein phosphatase 2 activity|inhibition of protein phosphatase 3 activity|inhibition of calcineurin activity http://purl.obolibrary.org/obo/GO_0032515 GO:0007559 biolink:BiologicalProcess obsolete histolysis OBSOLETE. The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue. Wikipedia:Histolysis go-plus.json http://purl.obolibrary.org/obo/GO_0007559 GO:0007558 biolink:BiologicalProcess regulation of juvenile hormone secretion Any process that modulates the frequency, rate or extent of juvenile hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0007558 GO:0032514 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032514 GO:0007557 biolink:BiologicalProcess regulation of juvenile hormone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. go-plus.json regulation of juvenile hormone anabolism|regulation of juvenile hormone synthesis|regulation of juvenile hormone formation|regulation of juvenile hormone biosynthesis http://purl.obolibrary.org/obo/GO_0007557 GO:0032513 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032513 GO:0032512 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032512 GO:0007556 biolink:BiologicalProcess regulation of juvenile hormone metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. go-plus.json regulation of juvenile hormone metabolism http://purl.obolibrary.org/obo/GO_0007556 GO:0007555 biolink:BiologicalProcess regulation of ecdysteroid secretion Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0007555 GO:0007554 biolink:BiologicalProcess regulation of ecdysteroid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. go-plus.json regulation of ecdysteroid biosynthesis|regulation of ecdysteroid anabolism|regulation of ecdysteroid synthesis|regulation of ecdysteroid formation http://purl.obolibrary.org/obo/GO_0007554 GO:0007553 biolink:BiologicalProcess regulation of ecdysteroid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females. go-plus.json regulation of ecdysteroid metabolism http://purl.obolibrary.org/obo/GO_0007553 GO:0007552 biolink:BiologicalProcess metamorphosis A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster. Wikipedia:Metamorphosis go-plus.json http://purl.obolibrary.org/obo/GO_0007552 GO:0007551 biolink:BiologicalProcess obsolete maintenance of dosage compensation OBSOLETE. (Was not defined before being made obsolete). go-plus.json maintenance of dosage compensation http://purl.obolibrary.org/obo/GO_0007551 GO:0007550 biolink:BiologicalProcess obsolete establishment of dosage compensation OBSOLETE. (Was not defined before being made obsolete). go-plus.json establishment of dosage compensation http://purl.obolibrary.org/obo/GO_0007550 GO:0032511 biolink:BiologicalProcess late endosome to vacuole transport via multivesicular body sorting pathway The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole. go-plus.json endosome to vacuole transport via MVB sorting pathway http://purl.obolibrary.org/obo/GO_0032511 GO:0032510 biolink:BiologicalProcess endosome to lysosome transport via multivesicular body sorting pathway The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. go-plus.json endosome to lysosome transport via MVB sorting pathway http://purl.obolibrary.org/obo/GO_0032510 CHEBI:137211 biolink:ChemicalSubstance (E)-2-(indol-3-yl)-1-thioacetohydroximic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137211 GO:0032508 biolink:BiologicalProcess DNA duplex unwinding The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands. go-plus.json duplex DNA melting|DNA unwinding http://purl.obolibrary.org/obo/GO_0032508 GO:0032507 biolink:BiologicalProcess maintenance of protein location in cell Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. go-plus.json maintenance of protein localization in cell http://purl.obolibrary.org/obo/GO_0032507 GO:0032506 biolink:BiologicalProcess cytokinetic process A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells). go-plus.json http://purl.obolibrary.org/obo/GO_0032506 GO:0032505 biolink:BiologicalProcess reproduction of a single-celled organism The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. go-plus.json http://purl.obolibrary.org/obo/GO_0032505 GO:0032504 biolink:BiologicalProcess multicellular organism reproduction The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. go-plus.json http://purl.obolibrary.org/obo/GO_0032504 GO:0007569 biolink:BiologicalProcess cell aging An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469). go-plus.json cell ageing http://purl.obolibrary.org/obo/GO_0007569 GO:0032503 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032503 GO:0007568 biolink:BiologicalProcess aging A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700). Wikipedia:Aging go-plus.json ageing http://purl.obolibrary.org/obo/GO_0007568 goslim_generic|goslim_chembl GO:0032502 biolink:BiologicalProcess developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. go-plus.json single-organism developmental process|development http://purl.obolibrary.org/obo/GO_0032502 goslim_flybase_ribbon|goslim_agr|goslim_pir|goslim_aspergillus GO:0032501 biolink:BiologicalProcess multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. go-plus.json single-multicellular organism process|organismal physiological process http://purl.obolibrary.org/obo/GO_0032501 gocheck_do_not_annotate|goslim_pir GO:0007567 biolink:BiologicalProcess parturition The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs. go-plus.json giving birth|egg laying http://purl.obolibrary.org/obo/GO_0007567 GO:0007566 biolink:BiologicalProcess embryo implantation Attachment of the blastocyst to the uterine lining. go-plus.json blastocyst implantation http://purl.obolibrary.org/obo/GO_0007566 GO:0007565 biolink:BiologicalProcess female pregnancy The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. Wikipedia:Gestation go-plus.json carrying of young|gestation http://purl.obolibrary.org/obo/GO_0007565 goslim_chembl GO:0007564 biolink:BiologicalProcess regulation of chitin-based cuticle tanning Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning. go-plus.json regulation of cuticle tanning|regulation of cuticle hardening http://purl.obolibrary.org/obo/GO_0007564 GO:0007563 biolink:BiologicalProcess regulation of eclosion Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg. go-plus.json http://purl.obolibrary.org/obo/GO_0007563 GO:0007562 biolink:BiologicalProcess eclosion The emergence of an adult insect from a pupa case. Wikipedia:Pupa#Emergence go-plus.json http://purl.obolibrary.org/obo/GO_0007562 GO:0007561 biolink:BiologicalProcess imaginal disc eversion The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0007561 GO:0007560 biolink:BiologicalProcess imaginal disc morphogenesis The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. go-plus.json imaginal disc metamorphosis http://purl.obolibrary.org/obo/GO_0007560 GO:0032509 biolink:BiologicalProcess endosome transport via multivesicular body sorting pathway The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment. go-plus.json endosome transport via MVB sorting pathway http://purl.obolibrary.org/obo/GO_0032509 GO:0032500 biolink:MolecularActivity muramyl dipeptide binding Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0032500 NCBITaxon:2811504 biolink:OrganismalEntity Thermodesulfovibrionaceae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2811504 NCBITaxon:2811503 biolink:OrganismalEntity Thermodesulfovibrionales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2811503 NCBITaxon:2811502 biolink:OrganismalEntity Thermodesulfovibrionia go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2811502 OBO:GOCHE_24432 biolink:OntologyClass substance with biological role role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24432 3_STAR GO:0007539 biolink:BiologicalProcess primary sex determination, soma The transmission of information about sexual status from the initial, general, determination to signals specific to the soma. go-plus.json http://purl.obolibrary.org/obo/GO_0007539 GO:0007538 biolink:BiologicalProcess primary sex determination The sex determination process that results in the initial specification of sexual status of an individual organism. go-plus.json http://purl.obolibrary.org/obo/GO_0007538 GO:0007537 biolink:BiologicalProcess inactivation of recombination (HML) The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0007537 GO:0007536 biolink:BiologicalProcess activation of recombination (HML) The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae. go-plus.json http://purl.obolibrary.org/obo/GO_0007536 GO:0007535 biolink:BiologicalProcess donor selection The process that determines which donor locus a cell uses, in preference to another, in mating type switching. go-plus.json donor preference http://purl.obolibrary.org/obo/GO_0007535 GO:0007534 biolink:BiologicalProcess gene conversion at mating-type locus The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged. go-plus.json gene conversion at mating-type locus, termination of copy-synthesis|gene conversion at mating-type locus, DNA double-strand break formation|heteroduplex formation involved in gene conversion at mating-type locus|gene conversion at mating-type locus, DNA repair synthesis|strand invasion involved in gene conversion at mating-type locus|gene conversion at mating-type locus, DNA double-strand break processing http://purl.obolibrary.org/obo/GO_0007534 GO:0007533 biolink:BiologicalProcess mating type switching The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus. go-plus.json mating type switching and recombination http://purl.obolibrary.org/obo/GO_0007533 GO:0007532 biolink:BiologicalProcess regulation of mating-type specific transcription, DNA-templated Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription. go-plus.json regulation of mating-type specific transcription, DNA-dependent|mating-type specific transcriptional control http://purl.obolibrary.org/obo/GO_0007532 GO:0007531 biolink:BiologicalProcess mating type determination Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0007531 GO:0007530 biolink:BiologicalProcess sex determination Any process that establishes and transmits the specification of sexual status of an individual organism. Wikipedia:Sex-determination_system go-plus.json http://purl.obolibrary.org/obo/GO_0007530 GO:0007549 biolink:BiologicalProcess dosage compensation Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. Wikipedia:Dosage_compensation go-plus.json http://purl.obolibrary.org/obo/GO_0007549 GO:0007548 biolink:BiologicalProcess sex differentiation The establishment of the sex of an organism by physical differentiation. Wikipedia:Sexual_differentiation go-plus.json http://purl.obolibrary.org/obo/GO_0007548 GO:0007547 biolink:BiologicalProcess germ-line processes downstream of sex determination signal The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0007547 GO:0007546 biolink:BiologicalProcess somatic processes downstream of sex determination signal The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0007546 GO:0007545 biolink:BiologicalProcess processes downstream of sex determination signal The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways. go-plus.json http://purl.obolibrary.org/obo/GO_0007545 GO:0007544 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007544 GO:0007543 biolink:BiologicalProcess sex determination, somatic-gonadal interaction The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism. go-plus.json sex determination, somatic/gonadal interaction http://purl.obolibrary.org/obo/GO_0007543 GO:0007542 biolink:BiologicalProcess primary sex determination, germ-line The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line. go-plus.json http://purl.obolibrary.org/obo/GO_0007542 GO:0007541 biolink:BiologicalProcess sex determination, primary response to X:A ratio The developmental process in which an organism interprets its X to autosomal chromosomal complement. go-plus.json http://purl.obolibrary.org/obo/GO_0007541 CHEBI:45599 biolink:ChemicalSubstance dodecyl hydrogen sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_45599 GO:0007540 biolink:BiologicalProcess sex determination, establishment of X:A ratio The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it. go-plus.json http://purl.obolibrary.org/obo/GO_0007540 CHEBI:137207 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137207 chebi_ph7_3 OBO:uberon/core#anteriorly_connected_to biolink:OntologyClass anteriorly connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. anteriorly_connected_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to UBERON:6007242 biolink:AnatomicalEntity insect embryonic/larval head sensillum Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730). go-plus.json larval head sensillum http://purl.obolibrary.org/obo/UBERON_6007242 UBERON:6007240 biolink:AnatomicalEntity insect embryonic/larval sensillum Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727). go-plus.json larval sensillum http://purl.obolibrary.org/obo/UBERON_6007240 CHEBI:69579 biolink:ChemicalSubstance hederagenin go-plus.json http://purl.obolibrary.org/obo/CHEBI_69579 GO:0032591 biolink:CellularComponent dendritic spine membrane The portion of the plasma membrane surrounding a dendritic spine. go-plus.json http://purl.obolibrary.org/obo/GO_0032591 GO:0032590 biolink:CellularComponent dendrite membrane The portion of the plasma membrane surrounding a dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0032590 NCBITaxon:32525 biolink:OrganismalEntity Theria go-plus.json Theria http://purl.obolibrary.org/obo/NCBITaxon_32525 GO:0032599 biolink:BiologicalProcess protein transport out of membrane raft The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. go-plus.json receptor translocation out of membrane raft|receptor transport out of membrane raft|protein translocation out of membrane raft|protein transport out of lipid raft http://purl.obolibrary.org/obo/GO_0032599 CHEBI:137297 biolink:ChemicalSubstance mycobilin b go-plus.json http://purl.obolibrary.org/obo/CHEBI_137297 GO:0032598 biolink:BiologicalProcess B cell receptor transport into immunological synapse The directed movement of a B cell receptor into an immunological synapse. go-plus.json BCR translocation into immunological synapse|B cell receptor translocation into immunological synapse|BCR transport into immunological synapse http://purl.obolibrary.org/obo/GO_0032598 GO:0032597 biolink:BiologicalProcess B cell receptor transport into membrane raft The directed movement of a B cell receptor into a membrane raft. go-plus.json BCR translocation into membrane raft|B cell receptor transport into lipid raft|B cell receptor translocation into membrane raft|BCR transport into membrane raft http://purl.obolibrary.org/obo/GO_0032597 NCBITaxon:32524 biolink:OrganismalEntity Amniota go-plus.json amniotes http://purl.obolibrary.org/obo/NCBITaxon_32524 GO:0032596 biolink:BiologicalProcess protein transport into membrane raft The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. go-plus.json protein transport into lipid raft|receptor translocation into membrane raft|protein translocation into membrane raft|receptor transport into membrane raft http://purl.obolibrary.org/obo/GO_0032596 NCBITaxon:32523 biolink:OrganismalEntity Tetrapoda go-plus.json tetrapods http://purl.obolibrary.org/obo/NCBITaxon_32523 GO:0032595 biolink:BiologicalProcess B cell receptor transport within lipid bilayer The directed movement of a B cell receptor within a lipid bilayer. go-plus.json BCR translocation within membrane|BCR transport within lipid bilayer|B cell receptor translocation within membrane http://purl.obolibrary.org/obo/GO_0032595 GO:0032594 biolink:BiologicalProcess protein transport within lipid bilayer The directed movement of a protein from one location to another within a lipid bilayer. go-plus.json protein translocation within membrane|receptor translocation within membrane|receptor transport within lipid bilayer http://purl.obolibrary.org/obo/GO_0032594 GO:0032593 biolink:CellularComponent insulin-responsive compartment A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2. go-plus.json GLUT4 storage compartment|IRC|GSC http://purl.obolibrary.org/obo/GO_0032593 CHEBI:137299 biolink:ChemicalSubstance biliverdin delta go-plus.json http://purl.obolibrary.org/obo/CHEBI_137299 GO:0032592 biolink:CellularComponent integral component of mitochondrial membrane The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to mitochondrial membrane http://purl.obolibrary.org/obo/GO_0032592 CHEBI:137298 biolink:ChemicalSubstance biliverdin beta go-plus.json http://purl.obolibrary.org/obo/CHEBI_137298 CHEBI:176839 biolink:ChemicalSubstance vitamin B3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_176839 CHEBI:176838 biolink:ChemicalSubstance vitamin B2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_176838 GO:0032589 biolink:CellularComponent neuron projection membrane The portion of the plasma membrane surrounding a neuron projection. go-plus.json http://purl.obolibrary.org/obo/GO_0032589 GO:0032580 biolink:CellularComponent Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. go-plus.json Golgi stack membrane http://purl.obolibrary.org/obo/GO_0032580 NCBITaxon:32519 biolink:OrganismalEntity Ostariophysi go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_32519 GO:0032588 biolink:CellularComponent trans-Golgi network membrane The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network. go-plus.json Golgi trans face membrane|trans Golgi network membrane http://purl.obolibrary.org/obo/GO_0032588 GO:0032587 biolink:CellularComponent ruffle membrane The portion of the plasma membrane surrounding a ruffle. go-plus.json membrane ruffle http://purl.obolibrary.org/obo/GO_0032587 GO:0032586 biolink:CellularComponent protein storage vacuole membrane The lipid bilayer surrounding a protein storage vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0032586 GO:0032585 biolink:CellularComponent multivesicular body membrane The lipid bilayer surrounding a multivesicular body. go-plus.json MVB membrane|multivesicular endosome membrane|MVE membrane http://purl.obolibrary.org/obo/GO_0032585 GO:0032584 biolink:CellularComponent growth cone membrane The portion of the plasma membrane surrounding a growth cone. go-plus.json http://purl.obolibrary.org/obo/GO_0032584 GO:0032583 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032583 GO:0032582 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032582 GO:0032581 biolink:BiologicalProcess ER-dependent peroxisome organization A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum. go-plus.json ER-dependent peroxisome biogenesis|ER-dependent peroxisome organisation|endoplasmic reticulum-dependent peroxisome organization http://purl.obolibrary.org/obo/GO_0032581 CHEBI:137281 biolink:ChemicalSubstance (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137281 GO:0032579 biolink:CellularComponent apical lamina of hyaline layer A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms. go-plus.json http://purl.obolibrary.org/obo/GO_0032579 GO:0032578 biolink:CellularComponent aleurone grain membrane The lipid bilayer surrounding an aleurone grain. go-plus.json http://purl.obolibrary.org/obo/GO_0032578 GO:0032577 biolink:MolecularActivity phosphatidylcholine:cardiolipin O-linoleoyltransferase activity Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule. go-plus.json phosphatidylcholine:cardiolipin linoleoyltransferase http://purl.obolibrary.org/obo/GO_0032577 GO:0032576 biolink:MolecularActivity O-linoleoyltransferase activity Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0032576 GO:0032575 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032575 GO:0032574 biolink:MolecularActivity 5'-3' RNA helicase activity Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis. Reactome:R-HSA-9682695|Reactome:R-HSA-9694265 go-plus.json 5' to 3' RNA helicase activity|ATP-dependent 5'-3' RNA helicase activity|ATP-dependent 5' to 3' RNA helicase activity http://purl.obolibrary.org/obo/GO_0032574 GO:0032573 biolink:BiologicalProcess response to phylloquinone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus. go-plus.json response to vitamin K1 http://purl.obolibrary.org/obo/GO_0032573 CHEBI:176843 biolink:ChemicalSubstance vitamin B12 go-plus.json http://purl.obolibrary.org/obo/CHEBI_176843 GO:0032572 biolink:BiologicalProcess response to menaquinone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus. go-plus.json response to menatetrenone|response to vitamin K2 http://purl.obolibrary.org/obo/GO_0032572 CHEBI:176842 biolink:ChemicalSubstance vitamin B9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_176842 GO:0032571 biolink:BiologicalProcess response to vitamin K Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032571 CHEBI:176841 biolink:ChemicalSubstance vitamin B7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_176841 GO:0032570 biolink:BiologicalProcess response to progesterone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. go-plus.json response to progesterone stimulus http://purl.obolibrary.org/obo/GO_0032570 CHEBI:176840 biolink:ChemicalSubstance vitamin B5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_176840 GO:0032569 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032569 GO:0032568 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032568 GO:0032567 biolink:MolecularActivity dGTP binding Binding to dGTP, deoxyguanosine triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032567 GO:0032566 biolink:MolecularActivity dGDP binding Binding to dGDP, deoxyguanosine diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032566 GO:0032565 biolink:MolecularActivity dGMP binding Binding to dGMP, deoxyguanosine monophosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032565 GO:0032564 biolink:MolecularActivity dATP binding Binding to dATP, deoxyadenosine triphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032564 GO:0032563 biolink:MolecularActivity dADP binding Binding to dADP, deoxyadenosine diphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032563 GO:0032562 biolink:MolecularActivity dAMP binding Binding to dAMP, deoxyadenosine monophosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032562 GO:0032561 biolink:MolecularActivity guanyl ribonucleotide binding Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032561 GO:0032560 biolink:MolecularActivity guanyl deoxyribonucleotide binding Binding to a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. go-plus.json http://purl.obolibrary.org/obo/GO_0032560 CHEBI:137287 biolink:ChemicalSubstance mycobilin a go-plus.json http://purl.obolibrary.org/obo/CHEBI_137287 GO:0140225 biolink:CellularComponent DNA topoisomerase III-beta-TDRD3 complex A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities. go-plus.json Top3-beta-TDRD3 complex http://purl.obolibrary.org/obo/GO_0140225 GO:0140224 biolink:CellularComponent SLAC complex A protein complex that regulates Arp2/3 complex-mediated actin nucleation. go-plus.json http://purl.obolibrary.org/obo/GO_0140224 GO:0140227 biolink:BiologicalProcess serotonin-gated cation-selective signaling pathway A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json 5-HT-gated cation-selective signalling pathway|5-HT-gated cation-selective signaling pathway|5-hydroxytryptamine-gated cation-selective signaling pathway|5-hydroxytryptamine-gated cation-selective signalling pathway|serotonin-gated cation-selective signalling pathway http://purl.obolibrary.org/obo/GO_0140227 GO:0140226 biolink:MolecularActivity RNA topoisomerase activity Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140226 GO:0140221 biolink:CellularComponent pathogen-containing vacuole membrane Host-derived membrane of a pathogen-containing vacuole. go-plus.json pathogen inclusion membrane|pathogen-containing compartment membrane http://purl.obolibrary.org/obo/GO_0140221 GO:0140220 biolink:CellularComponent pathogen-containing vacuole A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides. go-plus.json pathogen-containing compartment|pathogen inclusion http://purl.obolibrary.org/obo/GO_0140220 CHEBI:45506 biolink:ChemicalSubstance alpha-D-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_45506 chebi_ph7_3 GO:0140223 biolink:MolecularActivity general transcription initiation factor activity A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact subunit composition at individual promoters may vary. go-plus.json GTF activity|basal transcription factor activity|general transcription factor activity http://purl.obolibrary.org/obo/GO_0140223 GO:0140222 biolink:CellularComponent pathogen-containing vacuole lumen The enclosed volume within the sealed membrane of a pathogen-containing vacuole. go-plus.json pathogen-containing compartment lumen|pathogen inclusion lumen|lumen of a pathogen-containing vacuole|pathogen-containing vacuolar lumen http://purl.obolibrary.org/obo/GO_0140222 NCBITaxon:32561 biolink:OrganismalEntity Sauria go-plus.json Diapsida|diapsids http://purl.obolibrary.org/obo/NCBITaxon_32561 CHEBI:21545 biolink:ChemicalSubstance N-acetyl-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21545 GO:0140214 biolink:BiologicalProcess positive regulation of long-chain fatty acid import into cell Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140214 GO:0140213 biolink:BiologicalProcess negative regulation of long-chain fatty acid import into cell Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140213 GO:0140216 biolink:BiologicalProcess negative regulation of D-aspartate import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140216 GO:0140215 biolink:BiologicalProcess regulation of D-aspartate import across plasma membrane Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140215 GO:0140217 biolink:BiologicalProcess positive regulation of D-aspartate import across plasma membrane Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140217 GO:0140210 biolink:BiologicalProcess protein transport along microtubule to kinetochore Any process in which a protein is transported to the kinetochore along a microtubule. go-plus.json http://purl.obolibrary.org/obo/GO_0140210 GO:0140212 biolink:BiologicalProcess regulation of long-chain fatty acid import into cell Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140212 GO:0140211 biolink:MolecularActivity folic acid:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid. TC:2.A.1.50.1 go-plus.json http://purl.obolibrary.org/obo/GO_0140211 CHEBI:21547 biolink:ChemicalSubstance N-acetyl-L-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21547 CHEBI:21549 biolink:ChemicalSubstance N-acetyl-L-glutamate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_21549 GO:0140247 biolink:BiologicalProcess protein catabolic process at presynapse The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140247 goslim_synapse GO:0140246 biolink:BiologicalProcess protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140246 goslim_synapse GO:0140249 biolink:BiologicalProcess protein catabolic process at postsynapse The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140249 goslim_synapse GO:0140241 biolink:BiologicalProcess translation at synapse Translation that occurs at the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140241 goslim_synapse GO:0140240 biolink:CellularComponent perforant pathway to dendrate granule cell synapse A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus. go-plus.json perforant pathway to DG granule cell synapse http://purl.obolibrary.org/obo/GO_0140240 goslim_synapse GO:0140243 biolink:BiologicalProcess regulation of translation at synapse Any process that regulates translation occurring at the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140243 goslim_synapse GO:0140242 biolink:BiologicalProcess translation at postsynapse Translation that occurs at the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140242 goslim_synapse GO:0140245 biolink:BiologicalProcess regulation of translation at postsynapse Any process that regulates translation occurring at the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140245 goslim_synapse GO:0140244 biolink:BiologicalProcess regulation of translation at presynapse Any process that regulates translation occurring at the presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140244 goslim_synapse CHEBI:21519 biolink:ChemicalSubstance N-acetyl-D-glucosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21519 UBERON:0016570 biolink:AnatomicalEntity lamina of gray matter of spinal cord go-plus.json rexed lamina http://purl.obolibrary.org/obo/UBERON_0016570 GO:0140236 biolink:BiologicalProcess translation at presynapse Translation that occurs at the presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140236 goslim_synapse GO:0140235 biolink:BiologicalProcess RNA polyadenylation at postsynapse A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140235 goslim_synapse GO:0140238 biolink:BiologicalProcess presynaptic endocytosis A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0140238 goslim_synapse GO:0140237 biolink:BiologicalProcess translation at presynapse, modulating chemical synaptic transmission Translation that occurs at the presynapse, and that modulates chemical synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0140237 goslim_synapse GO:0140239 biolink:BiologicalProcess postsynaptic endocytosis A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0140239 goslim_synapse GO:0140232 biolink:MolecularActivity intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential. go-plus.json intracellular cAMP activated cation channel activity involved in regulation of presynaptic membrane potential http://purl.obolibrary.org/obo/GO_0140232 goslim_synapse GO:0140231 biolink:BiologicalProcess anterograde axonal transport of neurotransmitter receptor complex The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons. go-plus.json http://purl.obolibrary.org/obo/GO_0140231 goslim_synapse GO:0140233 biolink:MolecularActivity intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential. go-plus.json intracellular cAMP activated cation channel activity involved in regulation of postsynaptic membrane potential http://purl.obolibrary.org/obo/GO_0140233 goslim_synapse CHEBI:21524 biolink:ChemicalSubstance N-acetyl-D-glucosaminyl groups go-plus.json http://purl.obolibrary.org/obo/CHEBI_21524 CHEBI:21501 biolink:ChemicalSubstance N-acetyl-D-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21501 CHEBI:21500 biolink:ChemicalSubstance N-acetyl-9-O-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21500 CHEBI:21507 biolink:ChemicalSubstance N-acetyl-D-galactosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_21507 CHEBI:21509 biolink:ChemicalSubstance N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21509 GO:0140203 biolink:BiologicalProcess spermidine import across plasma membrane The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140203 GO:0140202 biolink:BiologicalProcess polyamine import across plasma membrane The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140202 GO:0140205 biolink:BiologicalProcess oligopeptide import across plasma membrane The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140205 GO:0140204 biolink:BiologicalProcess pyridoxal import across plasma membrane The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140204 GO:0140207 biolink:BiologicalProcess tripeptide import across plasma membrane The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140207 GO:0140206 biolink:BiologicalProcess dipeptide import across plasma membrane The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140206 GO:0140209 biolink:BiologicalProcess zinc ion import into endoplasmic reticulum The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum. go-plus.json zinc(2+) import into endoplasmic reticulum|zinc(2+) import across endoplasmic reticulum|zinc ion import across endoplasmic reticulum|zinc ion import into ER http://purl.obolibrary.org/obo/GO_0140209 GO:0140208 biolink:BiologicalProcess apoptotic process in response to mitochondrial fragmentation Any apoptotic process that occurs as a result of mitochondrial fragmentation. go-plus.json apoptosis in response to mitochondrial fragmentation http://purl.obolibrary.org/obo/GO_0140208 UBERON:6007149 biolink:AnatomicalEntity insect segment of antenna Any appendage segment that is part of some antenna. go-plus.json http://purl.obolibrary.org/obo/UBERON_6007149 GO:0140201 biolink:BiologicalProcess urea import across plasma membrane The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140201 GO:0140200 biolink:BiologicalProcess adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate An adrenergic receptor signaling pathway that modulates the frequency or rate of heart contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0140200 UBERON:6007150 biolink:AnatomicalEntity insect segment of leg Any appendage segment that is part of some leg. go-plus.json http://purl.obolibrary.org/obo/UBERON_6007150 GO:0007519 biolink:BiologicalProcess skeletal muscle tissue development The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. go-plus.json myogenesis http://purl.obolibrary.org/obo/GO_0007519 GO:0007518 biolink:BiologicalProcess myoblast fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0007518 GO:0007517 biolink:BiologicalProcess muscle organ development The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. go-plus.json http://purl.obolibrary.org/obo/GO_0007517 GO:0007516 biolink:BiologicalProcess hemocyte development The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. go-plus.json arthropod blood cell development http://purl.obolibrary.org/obo/GO_0007516 GO:0007515 biolink:BiologicalProcess obsolete lymph gland development OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system. go-plus.json lymph gland development http://purl.obolibrary.org/obo/GO_0007515 GO:1900998 biolink:BiologicalProcess nitrobenzene catabolic process The chemical reactions and pathways resulting in the breakdown of nitrobenzene. go-plus.json nitrobenzene degradation|nitrobenzene breakdown|nitrobenzene catabolism http://purl.obolibrary.org/obo/GO_1900998 GO:1900997 biolink:BiologicalProcess benzene biosynthetic process The chemical reactions and pathways resulting in the formation of benzene. go-plus.json benzene synthesis|benzene biosynthesis|benzene formation|benzene anabolism http://purl.obolibrary.org/obo/GO_1900997 GO:0007514 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007514 GO:0007513 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007513 GO:1900999 biolink:BiologicalProcess nitrobenzene biosynthetic process The chemical reactions and pathways resulting in the formation of nitrobenzene. go-plus.json nitrobenzene biosynthesis|nitrobenzene anabolism|nitrobenzene synthesis|nitrobenzene formation http://purl.obolibrary.org/obo/GO_1900999 GO:0007512 biolink:BiologicalProcess adult heart development The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure. go-plus.json adult cardiac development http://purl.obolibrary.org/obo/GO_0007512 GO:1900994 biolink:BiologicalProcess (-)-secologanin biosynthetic process The chemical reactions and pathways resulting in the formation of (-)-secologanin. go-plus.json (-)-secologanin formation|(-)-secologanin biosynthesis|(-)-secologanin anabolism|(-)-secologanin synthesis http://purl.obolibrary.org/obo/GO_1900994 GO:0007511 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007511 UBERON:0016525 biolink:AnatomicalEntity frontal lobe Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border. go-plus.json lobus frontalis|frontal region|frontal cortex|regio frontalis|lobi frontales http://purl.obolibrary.org/obo/UBERON_0016525 GO:1900993 biolink:BiologicalProcess (-)-secologanin catabolic process The chemical reactions and pathways resulting in the breakdown of (-)-secologanin. go-plus.json (-)-secologanin catabolism|(-)-secologanin degradation|(-)-secologanin breakdown http://purl.obolibrary.org/obo/GO_1900993 GO:0007510 biolink:BiologicalProcess cardioblast cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. go-plus.json http://purl.obolibrary.org/obo/GO_0007510 GO:1900996 biolink:BiologicalProcess benzene catabolic process The chemical reactions and pathways resulting in the breakdown of benzene. go-plus.json benzene catabolism|benzene degradation|benzene breakdown http://purl.obolibrary.org/obo/GO_1900996 UBERON:0016527 biolink:AnatomicalEntity white matter of cerebral lobe go-plus.json http://purl.obolibrary.org/obo/UBERON_0016527 UBERON:0016526 biolink:AnatomicalEntity lobe of cerebral hemisphere Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]. go-plus.json lobe of cerebral cortex|lobe parts of cerebral cortex|regional organ part of cerebral cortex|cerebral lobe|cerebral cortical segment|segment of cerebral cortex|cerebral hemisphere lobe|lobi cerebri|lobes of the brain http://purl.obolibrary.org/obo/UBERON_0016526 GO:1900995 biolink:MolecularActivity ubiquinone-6 binding Binding to ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2. go-plus.json http://purl.obolibrary.org/obo/GO_1900995 GO:1900990 biolink:BiologicalProcess scopolamine catabolic process The chemical reactions and pathways resulting in the breakdown of scopolamine. go-plus.json scopolamine degradation|scopolamine catabolism|scopolamine breakdown http://purl.obolibrary.org/obo/GO_1900990 UBERON:0016520 biolink:AnatomicalEntity epithelium of female urethra A epithelium that is part of a female urethra. go-plus.json urethral epithelium of female|female urethral epithelium http://purl.obolibrary.org/obo/UBERON_0016520 GO:1900992 biolink:BiologicalProcess (-)-secologanin metabolic process The chemical reactions and pathways involving (-)-secologanin. go-plus.json (-)-secologanin metabolism http://purl.obolibrary.org/obo/GO_1900992 GO:1900991 biolink:BiologicalProcess scopolamine biosynthetic process The chemical reactions and pathways resulting in the formation of scopolamine. go-plus.json scopolamine anabolism|scopolamine synthesis|scopolamine formation|scopolamine biosynthesis http://purl.obolibrary.org/obo/GO_1900991 UBERON:0016522 biolink:AnatomicalEntity cavity of right atrium luminal space of the right atrium of the heart. go-plus.json right atrial cavity http://purl.obolibrary.org/obo/UBERON_0016522 CHEBI:3543 biolink:ChemicalSubstance cephamycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_3543 NCBITaxon:8342 biolink:OrganismalEntity Anura go-plus.json frogs & toads|anurans|frogs and toads|Salientia|frogs http://purl.obolibrary.org/obo/NCBITaxon_8342 GO:0007529 biolink:BiologicalProcess establishment of synaptic specificity at neuromuscular junction The biological process in which a synapse between a motor neuron and a muscle is initially formed. go-plus.json http://purl.obolibrary.org/obo/GO_0007529 CHEBI:45571 biolink:ChemicalSubstance heptanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45571 GO:0007528 biolink:BiologicalProcess neuromuscular junction development A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. go-plus.json neuromuscular junction stability|NMJ stability|neuromuscular junction organization http://purl.obolibrary.org/obo/GO_0007528 GO:0007527 biolink:BiologicalProcess adult somatic muscle development The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007527 GO:0007526 biolink:BiologicalProcess larval somatic muscle development The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007526 GO:0007525 biolink:BiologicalProcess somatic muscle development The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle. go-plus.json http://purl.obolibrary.org/obo/GO_0007525 GO:0007524 biolink:BiologicalProcess adult visceral muscle development The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007524 GO:0007523 biolink:BiologicalProcess larval visceral muscle development The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007523 GO:0007522 biolink:BiologicalProcess visceral muscle development The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007522 UBERON:0016514 biolink:AnatomicalEntity cavity of left ventricle luminal space of the left ventricle of the heart. go-plus.json left ventricular cavity http://purl.obolibrary.org/obo/UBERON_0016514 UBERON:0016513 biolink:AnatomicalEntity cavity of left atrium luminal space of the left atrium of the heart. go-plus.json left atrium lumen|left atrial cavity http://purl.obolibrary.org/obo/UBERON_0016513 GO:0007521 biolink:BiologicalProcess muscle cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0007521 GO:0007520 biolink:BiologicalProcess myoblast fusion A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. go-plus.json http://purl.obolibrary.org/obo/GO_0007520 UBERON:0016510 biolink:AnatomicalEntity epithelium of male urethra A epithelium that is part of a male urethra. go-plus.json male urethral epithelium|urethral epithelium of male http://purl.obolibrary.org/obo/UBERON_0016510 UBERON:0016512 biolink:AnatomicalEntity lumen of duodenum A anatomical space that is part of a duodenum. go-plus.json duodenal lumen|doudenal lumen http://purl.obolibrary.org/obo/UBERON_0016512 GO:0140294 biolink:MolecularActivity NAD DNA ADP-ribosyltransferase activity Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140294 CHEBI:137305 biolink:ChemicalSubstance (9Z,12Z)-11-hydroxyoctadecadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137305 GO:0140293 biolink:MolecularActivity ADP-ribosylglutamate hydrolase activity Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose. go-plus.json http://purl.obolibrary.org/obo/GO_0140293 GO:0140296 biolink:MolecularActivity general transcription initiation factor binding Binding to a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation. go-plus.json http://purl.obolibrary.org/obo/GO_0140296 GO:0140295 biolink:MolecularActivity pathogen-derived receptor ligand activity The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity. go-plus.json innate receptor ligand activity http://purl.obolibrary.org/obo/GO_0140295 CHEBI:137302 biolink:ChemicalSubstance 7,7-dihydroxybacteriochlorophyllide c go-plus.json http://purl.obolibrary.org/obo/CHEBI_137302 GO:0140298 biolink:BiologicalProcess endocytic iron import into cell Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis. go-plus.json iron import into cell by endocytosis http://purl.obolibrary.org/obo/GO_0140298 GO:0140297 biolink:MolecularActivity DNA-binding transcription factor binding Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. go-plus.json activating transcription factor binding|repressing transcription factor binding|transcription activator binding http://purl.obolibrary.org/obo/GO_0140297 UBERON:0016509 biolink:AnatomicalEntity cavity of right ventricle Luminal space of the right ventricle of the heart. go-plus.json right ventricular cavity|right ventricle lumen http://purl.obolibrary.org/obo/UBERON_0016509 GO:0140299 biolink:MolecularActivity small molecule sensor activity Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule. go-plus.json small molecular sensor activity http://purl.obolibrary.org/obo/GO_0140299 GO:0140290 biolink:BiologicalProcess peptidyl-serine ADP-deribosylation The removal of ADP-ribose from ADP-ribosylserine. go-plus.json http://purl.obolibrary.org/obo/GO_0140290 NCBITaxon:8353 biolink:OrganismalEntity Xenopus go-plus.json Xenopus http://purl.obolibrary.org/obo/NCBITaxon_8353 CHEBI:137300 biolink:ChemicalSubstance bacteriochlorophyllide e go-plus.json http://purl.obolibrary.org/obo/CHEBI_137300 NCBITaxon:8352 biolink:OrganismalEntity Pipidae go-plus.json tongueless frogs|pipid frogs http://purl.obolibrary.org/obo/NCBITaxon_8352 GO:0140292 biolink:MolecularActivity ADP-ribosylserine hydrolase activity Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose. go-plus.json http://purl.obolibrary.org/obo/GO_0140292 GO:0140291 biolink:BiologicalProcess peptidyl-glutamate ADP-deribosylation The removal of ADP-ribose from ADP-ribosylglutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0140291 CHEBI:3528 biolink:ChemicalSubstance cellotriose go-plus.json http://purl.obolibrary.org/obo/CHEBI_3528 chebi_ph7_3 CHEBI:45564 biolink:ChemicalSubstance 5-hydroxypentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45564 CHEBI:3523 biolink:ChemicalSubstance cellodextrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3523 chebi_ph7_3 GO:0007508 biolink:BiologicalProcess larval heart development The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper. go-plus.json http://purl.obolibrary.org/obo/GO_0007508 GO:0007507 biolink:BiologicalProcess heart development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. Wikipedia:Heart_development go-plus.json cardiac development|dorsal vessel development http://purl.obolibrary.org/obo/GO_0007507 GO:0007506 biolink:BiologicalProcess gonadal mesoderm development The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0007506 GO:0007505 biolink:BiologicalProcess adult fat body development The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body. go-plus.json http://purl.obolibrary.org/obo/GO_0007505 GO:0007504 biolink:BiologicalProcess larval fat body development The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life. go-plus.json http://purl.obolibrary.org/obo/GO_0007504 GO:0007503 biolink:BiologicalProcess fat body development The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0007503 GO:0007502 biolink:BiologicalProcess digestive tract mesoderm development The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0007502 GO:0007501 biolink:BiologicalProcess mesodermal cell fate specification The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. go-plus.json mesoderm cell fate specification http://purl.obolibrary.org/obo/GO_0007501 GO:0007500 biolink:BiologicalProcess mesodermal cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json mesoderm cell fate determination http://purl.obolibrary.org/obo/GO_0007500 CHEBI:45557 biolink:ChemicalSubstance sec-butyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_45557 chebi_ph7_3 GO:0007509 biolink:BiologicalProcess mesoderm migration involved in gastrulation The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0007509 CHEBI:21575 biolink:ChemicalSubstance N-acetyl-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21575 UBERON:0016569 biolink:AnatomicalEntity subcupular meshwork of statoconial membrane An acellular membrane in the inner ear that is part of the statoconial membrane and consists of long branching filaments cross-bridged to one another. The filaments are continuous with those of the otolithic membrane on one side and with the surface of the epithelium on the other. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016569 GO:0140268 biolink:CellularComponent endoplasmic reticulum-plasma membrane contact site A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes. go-plus.json ER-PM contact site|endoplasmic reticulum-plasma membrane contact junction|EPCS|ER-plasma membrane contact site http://purl.obolibrary.org/obo/GO_0140268 UBERON:0016565 biolink:AnatomicalEntity cerebral blood vessel A blood vessel that is part of a cerebellum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016565 UBERON:0016567 biolink:AnatomicalEntity statoconial membrane An acellular membrane in the vestibular labyrinth that is composed of the otoconial layer, gelatinous layer, and a subcupular meshwork. go-plus.json otolith membrane|otoconial-statoconial membrane http://purl.obolibrary.org/obo/UBERON_0016567 UBERON:0016566 biolink:AnatomicalEntity pit An roughly circular indentation in a surface. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016566 GO:0140261 biolink:CellularComponent BCOR complex A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10. go-plus.json non-canonical PRC1-BCOR complex|BCOR/BCORL1 complex|PRC1.1 complex|non-canonical BCOR-PRC1.1 complex|BCL6 corepressor (BCOR) complex http://purl.obolibrary.org/obo/GO_0140261 GO:0140260 biolink:MolecularActivity mitochondrial proton-transporting ATP synthase complex binding Binding to a mitochondrial proton-transporting ATP synthase complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140260 NCBITaxon:81529 biolink:OrganismalEntity Salpingoecidae go-plus.json Codonosigidae|Monosigidae http://purl.obolibrary.org/obo/NCBITaxon_81529 GO:0140262 biolink:MolecularActivity mRNA cap binding complex binding Binding to a mRNA cap binding complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140262 GO:0140267 biolink:BiologicalProcess viral entry via permeabilization of host membrane The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0140267 gocheck_do_not_annotate GO:0140266 biolink:CellularComponent Woronin body Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes. go-plus.json http://purl.obolibrary.org/obo/GO_0140266 UBERON:0016550 biolink:AnatomicalEntity spinal cord column go-plus.json http://purl.obolibrary.org/obo/UBERON_0016550 UBERON:0016552 biolink:AnatomicalEntity phlegm mucus produced in the respiratory tract. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016552 GO:0140259 biolink:MolecularActivity PRC1 complex binding Binding to a PRC1 complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140259 UBERON:0016554 biolink:AnatomicalEntity white matter of midbrain A white matter that is part of the midbrain. go-plus.json mesencephalic white matter http://purl.obolibrary.org/obo/UBERON_0016554 UBERON:0016553 biolink:AnatomicalEntity respiratory system mucus Any mucus produced by a mucosae of the respiratory system. This includes the mucus produced in the nasal cavity (nasal mucus) and mucus produced in the respiratory tract (phlegm). go-plus.json http://purl.obolibrary.org/obo/UBERON_0016553 NCBITaxon:81525 biolink:OrganismalEntity Monosiga go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_81525 GO:0140250 biolink:BiologicalProcess regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140250 goslim_synapse GO:0140252 biolink:BiologicalProcess regulation protein catabolic process at postsynapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140252 goslim_synapse GO:0140251 biolink:BiologicalProcess regulation protein catabolic process at presynapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0140251 goslim_synapse GO:0140253 biolink:BiologicalProcess cell-cell fusion A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. go-plus.json cell fusion|cell cell fusion http://purl.obolibrary.org/obo/GO_0140253 GO:0140256 biolink:BiologicalProcess negative regulation of cellular response to phosphate starvation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0140256 GO:0140255 biolink:BiologicalProcess regulation of cellular response to phosphate starvation Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation. go-plus.json http://purl.obolibrary.org/obo/GO_0140255 CHEBI:45525 biolink:ChemicalSubstance (R)-2-methylbutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45525 UBERON:0016549 biolink:AnatomicalEntity central nervous system white matter layer A layer of of the central nervous system that is composed of white matter. go-plus.json white matter layer of neuraxis|CNS white matter layer|white matter layer http://purl.obolibrary.org/obo/UBERON_0016549 CHEBI:45522 biolink:ChemicalSubstance O-phospho-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_45522 UBERON:0016548 biolink:AnatomicalEntity central nervous system gray matter layer A layer of of the central nervous system that is part of gray matter. go-plus.json CNS grey matter layer|CNS gray matter layer|grey matter layer of neuraxis|gray matter layer of neuraxis|grey matter layer http://purl.obolibrary.org/obo/UBERON_0016548 UBERON:0016542 biolink:AnatomicalEntity limbic cortex go-plus.json cortex of limbic lobe|gray matter of limbic lobe|limbic lobe cortex http://purl.obolibrary.org/obo/UBERON_0016542 UBERON:0016545 biolink:AnatomicalEntity pharyngeal ectoderm The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016545 GO:0140282 biolink:MolecularActivity carbon-nitrogen ligase activity on lipid II Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate. RHEA:57928|EC:6.3.5.13 go-plus.json L-glutamate--lipid II transaminase activity|undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl pentapeptide amidotransferase (glutamine-hydrolyzing) activity|carbon-nitrogen ligase activity on lipid II http://purl.obolibrary.org/obo/GO_0140282 NCBITaxon:8360 biolink:OrganismalEntity Xenopodinae go-plus.json Siluraninae http://purl.obolibrary.org/obo/NCBITaxon_8360 GO:0140285 biolink:BiologicalProcess endosome fission The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140285 GO:0140284 biolink:CellularComponent endoplasmic reticulum-endosome membrane contact site A contact site between the endoplasmic reticulum membrane and the endosome membrane. go-plus.json ER-endosome membrane contact site http://purl.obolibrary.org/obo/GO_0140284 GO:0140289 biolink:BiologicalProcess protein mono-ADP-ribosylation The transfer, from NAD, of a single (mono) ADP-ribose molecule to protein amino acids. go-plus.json http://purl.obolibrary.org/obo/GO_0140289 GO:0140288 biolink:CellularComponent GBAF complex A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM. go-plus.json http://purl.obolibrary.org/obo/GO_0140288 CHEBI:21557 biolink:ChemicalSubstance N-acetyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21557 NCBITaxon:8364 biolink:OrganismalEntity Xenopus tropicalis go-plus.json Xenopus laevis tropicalis|western clawed frog|tropical clawed frog|Xenopus (Silurana) tropicalis|Silurana tropicalis http://purl.obolibrary.org/obo/NCBITaxon_8364 GO:0140281 biolink:BiologicalProcess positive regulation of mitotic division septum assembly Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. go-plus.json up regulation of division septum formation involved in mitotic cell cycle|up-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of mitotic division septum assembly|positive regulation of septin assembly and septum formation involved in mitotic cell cycle|up regulation of formation of division septum involved in mitotic cell cycle|up-regulation of mitotic division septum assembly|positive regulation of formation of division septum involved in mitotic cell cycle|activation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up-regulation of septin assembly and septum formation involved in mitotic cell cycle|upregulation of division septum formation involved in mitotic cell cycle|positive regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of formation of division septum involved in mitotic cell cycle|activation of mitotic division septum assembly|up regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|upregulation of septin assembly and septum formation involved in mitotic cell cycle|up-regulation of formation of division septum involved in mitotic cell cycle|up-regulation of division septum formation involved in mitotic cell cycle|up regulation of mitotic division septum assembly|upregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of division septum formation involved in mitotic cell cycle|upregulation of formation of division septum involved in mitotic cell cycle|up regulation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of division septum formation involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_0140281 NCBITaxon:8363 biolink:OrganismalEntity Silurana go-plus.json Xenopus tropicalis group http://purl.obolibrary.org/obo/NCBITaxon_8363 GO:0140280 biolink:BiologicalProcess negative regulation of mitotic division septum assembly Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. go-plus.json down-regulation of septin assembly and septum formation involved in mitotic cell cycle|negative regulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|downregulation of mitotic division septum assembly|negative regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|down-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|inhibition of division septum formation involved in mitotic cell cycle|negative regulation of division septum formation involved in mitotic cell cycle|down-regulation of division septum formation involved in mitotic cell cycle|down regulation of mitotic division septum assembly|inhibition of septin assembly and septum formation involved in mitotic cell cycle|down regulation of formation of division septum involved in mitotic cell cycle|downregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|inhibition of formation of division septum involved in mitotic cell cycle|downregulation of formation of division septum involved in mitotic cell cycle|downregulation of division septum formation involved in mitotic cell cycle|downregulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of division septum formation involved in mitotic cell cycle|inhibition of septin assembly and septum biosynthesis involved in mitotic cell cycle|inhibition of mitotic division septum assembly|down-regulation of formation of division septum involved in mitotic cell cycle|negative regulation of formation of division septum involved in mitotic cell cycle|down-regulation of mitotic division septum assembly http://purl.obolibrary.org/obo/GO_0140280 UBERON:0016530 biolink:AnatomicalEntity parietal cortex Gray matter of the parietal region of the neocortex, located in the parietal lobe of gyrencephalic animals. It is continuous anteriorly with the frontal cortex, posteriorly with the occipital cortex and medially with the insular cortex and with the temporal cortex on the posterior/inferior border. go-plus.json parietal lobe cortex|parietal neocortex|cortex of parietal lobe|gray matter of parietal lobe http://purl.obolibrary.org/obo/UBERON_0016530 CHEBI:21565 biolink:ChemicalSubstance N-acetyl-L-valine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21565 UBERON:0016536 biolink:AnatomicalEntity white matter of limbic lobe A white matter of cerebral lobe that is part of a limbic lobe. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016536 GO:0140279 biolink:BiologicalProcess regulation of mitotic division septum assembly Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. go-plus.json regulation of formation of division septum involved in mitotic cell cycle|regulation of division septum formation involved in mitotic cell cycle|regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|regulation of septin assembly and septum formation involved in mitotic cell cycle http://purl.obolibrary.org/obo/GO_0140279 UBERON:0016538 biolink:AnatomicalEntity temporal cortex Gray matter of the temporal region of the neocortex, located in the temporal lobe in gyrencephalic animals go-plus.json gray matter of temporal lobe|temporal lobe cortex|temporal neocortex|cortex of temporal lobe http://purl.obolibrary.org/obo/UBERON_0016538 UBERON:0016531 biolink:AnatomicalEntity white matter of parietal lobe A white matter of cerebral lobe that is part of a parietal lobe. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016531 UBERON:0016534 biolink:AnatomicalEntity white matter of temporal lobe A white matter of cerebral lobe that is part of a temporal lobe. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016534 GO:0140272 biolink:MolecularActivity exogenous protein binding Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140272 CHEBI:3576 biolink:ChemicalSubstance chanoclavine-I go-plus.json http://purl.obolibrary.org/obo/CHEBI_3576 GO:0140271 biolink:BiologicalProcess hexose import across plasma membrane The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140271 GO:0140274 biolink:BiologicalProcess repair of kinetochore microtubule attachment defect The cell cycle process where kinetochore microtubule attachment defects are corrected. go-plus.json repair of kinetochore microtubule attachment defects|correction of kinetochore microtubule attachment defects http://purl.obolibrary.org/obo/GO_0140274 GO:0140273 biolink:BiologicalProcess repair of mitotic kinetochore microtubule attachment defect The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected. go-plus.json correction of mitotic kinetochore microtubule attachment defects|repair of mitotic kinetochore microtubule attachment defects http://purl.obolibrary.org/obo/GO_0140273 GO:0140276 biolink:BiologicalProcess obsolete pericentric heterochromatin maintenance OBSOLETE. Any heterochromatin maintenance that is involved in chromatin silencing at or near a centromere. go-plus.json heterochromatin maintenance involved in chromatin silencing at centromeric outer repeats|heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region|heterochromatin maintenance involved in chromatin silencing at pericentric region http://purl.obolibrary.org/obo/GO_0140276 UBERON:0016529 biolink:AnatomicalEntity cortex of cerebral lobe Grey matter neocortex region of a lobe of the cerebral hemisphere. go-plus.json neocortical part of cerebral hemisphere|cortex of lobe of cerebral hemisphere|gray matter of lobe of cerebral hemisphere|cortex of cerebral hemisphere lobe http://purl.obolibrary.org/obo/UBERON_0016529 GO:0140275 biolink:CellularComponent MIB complex A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1. go-plus.json mitochondrial intermembrane space bridging complex|mitofilin complex http://purl.obolibrary.org/obo/GO_0140275 UBERON:0016528 biolink:AnatomicalEntity white matter of frontal lobe A white matter of cerebral lobe that is part of a frontal lobe. go-plus.json frontal lobe white matter http://purl.obolibrary.org/obo/UBERON_0016528 GO:0140278 biolink:BiologicalProcess mitotic division septum assembly The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material. go-plus.json http://purl.obolibrary.org/obo/GO_0140278 CHEBI:21569 biolink:ChemicalSubstance N-acetyl-O-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21569 GO:0140270 biolink:BiologicalProcess gluconate import across plasma membrane The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140270 GO:0017040 biolink:MolecularActivity N-acylsphingosine amidohydrolase activity Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine. MetaCyc:CERAMIDASE-RXN|Reactome:R-HSA-1606583|Reactome:R-HSA-1606602|RHEA:20856|Reactome:R-HSA-428205|EC:3.5.1.23|Reactome:R-HSA-428231 go-plus.json acylsphingosine deacylase activity|N-acylsphingosine amidohydrolase activity|glycosphingolipid ceramide deacylase http://purl.obolibrary.org/obo/GO_0017040 GO:0032679 biolink:BiologicalProcess regulation of TRAIL production Any process that modulates the frequency, rate, or extent of TRAIL production. go-plus.json regulation of TRAIL biosynthetic process http://purl.obolibrary.org/obo/GO_0032679 GO:0032678 biolink:BiologicalProcess regulation of interleukin-9 production Any process that modulates the frequency, rate, or extent of interleukin-9 production. go-plus.json regulation of IL-9 production|regulation of interleukin-9 biosynthetic process http://purl.obolibrary.org/obo/GO_0032678 GO:0032677 biolink:BiologicalProcess regulation of interleukin-8 production Any process that modulates the frequency, rate, or extent of interleukin-8 production. go-plus.json regulation of IL-8 production|regulation of interleukin-8 biosynthetic process|regulation of interleukin-8 secretion http://purl.obolibrary.org/obo/GO_0032677 GO:0042002 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042002 GO:0042001 biolink:BiologicalProcess hermaphrodite somatic sex determination The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0042001 GO:0042004 biolink:BiologicalProcess feminization of hermaphrodite soma Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0042004 GO:0042003 biolink:BiologicalProcess masculinization of hermaphrodite soma Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0042003 GO:0042000 biolink:BiologicalProcess translocation of peptides or proteins into host The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json transport of peptides or proteins into other organism during symbiotic interaction|translocation of peptides or proteins into other organism involved in symbiotic interaction|transport of peptides or proteins into host|translocation of peptides or proteins into other organism during symbiotic interaction http://purl.obolibrary.org/obo/GO_0042000 GO:0042009 biolink:MolecularActivity interleukin-15 binding Binding to interleukin-15. go-plus.json IL-15 binding http://purl.obolibrary.org/obo/GO_0042009 GO:0017039 biolink:MolecularActivity obsolete dipeptidyl-peptidase III activity OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides. go-plus.json DPP III activity|dipeptidyl-peptidase III activity|red cell angiotensinase activity|dipeptidyl arylamidase III activity|dipeptidyl aminopeptidase III activity|enkephalinase B activity http://purl.obolibrary.org/obo/GO_0017039 GO:0042006 biolink:BiologicalProcess masculinization of hermaphroditic germ-line The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0042006 GO:0017038 biolink:BiologicalProcess protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event. go-plus.json protein uptake http://purl.obolibrary.org/obo/GO_0017038 GO:0042005 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042005 GO:0042008 biolink:MolecularActivity interleukin-18 receptor activity Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-18R|IL-18 receptor activity http://purl.obolibrary.org/obo/GO_0042008 GO:0042007 biolink:MolecularActivity interleukin-18 binding Binding to interleukin-18. go-plus.json IL-18 binding http://purl.obolibrary.org/obo/GO_0042007 GO:0032676 biolink:BiologicalProcess regulation of interleukin-7 production Any process that modulates the frequency, rate, or extent of interleukin-7 production. go-plus.json regulation of interleukin-7 biosynthetic process|regulation of interleukin-7 secretion|regulation of IL-7 production http://purl.obolibrary.org/obo/GO_0032676 GO:0017035 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017035 CHEBI:3381 biolink:ChemicalSubstance (-)-car-3-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_3381 chebi_ph7_3 GO:0032675 biolink:BiologicalProcess regulation of interleukin-6 production Any process that modulates the frequency, rate, or extent of interleukin-6 production. go-plus.json regulation of interleukin-6 biosynthetic process|regulation of IL-6 production http://purl.obolibrary.org/obo/GO_0032675 GO:0017034 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017034 GO:0032674 biolink:BiologicalProcess regulation of interleukin-5 production Any process that modulates the frequency, rate, or extent of interleukin-5 production. go-plus.json regulation of interleukin-5 biosynthetic process|regulation of interleukin-5 secretion|regulation of IL-5 production http://purl.obolibrary.org/obo/GO_0032674 GO:0017037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017037 GO:0032673 biolink:BiologicalProcess regulation of interleukin-4 production Any process that modulates the frequency, rate, or extent of interleukin-4 production. go-plus.json regulation of interleukin-4 biosynthetic process|regulation of interleukin-4 secretion|regulation of IL-4 production http://purl.obolibrary.org/obo/GO_0032673 GO:0017036 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017036 GO:0032672 biolink:BiologicalProcess regulation of interleukin-3 production Any process that modulates the frequency, rate, or extent of interleukin-3 production. go-plus.json regulation of interleukin-3 biosynthetic process|regulation of IL-3 production http://purl.obolibrary.org/obo/GO_0032672 GO:0017031 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017031 GO:0017030 biolink:MolecularActivity obsolete beta-galactosidase stabilization activity OBSOLETE. Stabilization of the structure of beta-galactosidase. go-plus.json beta-galactosidase stabilization activity http://purl.obolibrary.org/obo/GO_0017030 GO:0032671 biolink:BiologicalProcess regulation of interleukin-27 production Any process that modulates the frequency, rate, or extent of interleukin-27 production. go-plus.json regulation of interleukin-27 synthesis|regulation of interleukin-27 formation|regulation of IL-27 production|regulation of interleukin-27 biosynthetic process http://purl.obolibrary.org/obo/GO_0032671 GO:0032670 biolink:BiologicalProcess regulation of interleukin-26 production Any process that modulates the frequency, rate, or extent of interleukin-26 production. go-plus.json regulation of IL-26 production|regulation of interleukin-26 biosynthetic process http://purl.obolibrary.org/obo/GO_0032670 GO:0017033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017033 GO:0017032 biolink:MolecularActivity amino acid:potassium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in). go-plus.json potassium:amino acid symporter activity http://purl.obolibrary.org/obo/GO_0017032 GO:0017051 biolink:MolecularActivity retinol dehydratase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol. go-plus.json http://purl.obolibrary.org/obo/GO_0017051 GO:0017050 biolink:MolecularActivity D-erythro-sphingosine kinase activity Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP. Reactome:R-HSA-5218845|RHEA:35847|MetaCyc:RXN3DJ-11417|Reactome:R-HSA-9695949|Reactome:R-HSA-9625814|Reactome:R-HSA-428273 go-plus.json sphingosine kinase activity http://purl.obolibrary.org/obo/GO_0017050 GO:0032669 biolink:BiologicalProcess regulation of interleukin-25 production Any process that modulates the frequency, rate, or extent of interleukin-25 production. go-plus.json regulation of IL-25 production|regulation of interleukin-25 biosynthetic process|regulation of interleukin-25 secretion http://purl.obolibrary.org/obo/GO_0032669 GO:0032668 biolink:BiologicalProcess regulation of interleukin-24 production Any process that modulates the frequency, rate, or extent of interleukin-24 production. go-plus.json regulation of IL-24 production|regulation of interleukin-24 biosynthetic process http://purl.obolibrary.org/obo/GO_0032668 GO:0032667 biolink:BiologicalProcess regulation of interleukin-23 production Any process that modulates the frequency, rate, or extent of interleukin-23 production. go-plus.json regulation of interleukin-23 synthesis|regulation of interleukin-23 formation|regulation of interleukin-23 biosynthesis|regulation of interleukin-23 biosynthetic process|regulation of IL-23 production|regulation of IL-23 biosynthetic process|regulation of interleukin-23 anabolism http://purl.obolibrary.org/obo/GO_0032667 GO:0032666 biolink:BiologicalProcess regulation of interleukin-22 production Any process that modulates the frequency, rate, or extent of interleukin-22 production. go-plus.json regulation of IL-22 production|regulation of interleukin-22 biosynthetic process http://purl.obolibrary.org/obo/GO_0032666 GO:0042013 biolink:MolecularActivity interleukin-19 binding Binding to interleukin-19. go-plus.json IL-19 binding http://purl.obolibrary.org/obo/GO_0042013 GO:0042012 biolink:MolecularActivity interleukin-16 receptor activity Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-16R|IL-16 receptor activity http://purl.obolibrary.org/obo/GO_0042012 GO:0042015 biolink:MolecularActivity interleukin-20 binding Binding to interleukin-20. go-plus.json IL-20 binding http://purl.obolibrary.org/obo/GO_0042015 GO:0042014 biolink:MolecularActivity interleukin-19 receptor activity Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-19 receptor activity|IL-19R http://purl.obolibrary.org/obo/GO_0042014 GO:0042011 biolink:MolecularActivity interleukin-16 binding Binding to interleukin-16. go-plus.json IL-16 binding http://purl.obolibrary.org/obo/GO_0042011 GO:0042010 biolink:MolecularActivity interleukin-15 receptor activity Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-15R|IL-15 receptor activity http://purl.obolibrary.org/obo/GO_0042010 GO:0042017 biolink:MolecularActivity interleukin-22 binding Binding to interleukin-22. go-plus.json IL-22 binding http://purl.obolibrary.org/obo/GO_0042017 GO:0042016 biolink:MolecularActivity interleukin-20 receptor activity Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-20 receptor activity|IL-20R http://purl.obolibrary.org/obo/GO_0042016 GO:0017049 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017049 GO:0042019 biolink:MolecularActivity interleukin-23 binding Binding to interleukin-23. go-plus.json IL-23 binding http://purl.obolibrary.org/obo/GO_0042019 GO:0042018 biolink:MolecularActivity interleukin-22 receptor activity Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-22R|IL-22 receptor activity http://purl.obolibrary.org/obo/GO_0042018 GO:0032665 biolink:BiologicalProcess regulation of interleukin-21 production Any process that modulates the frequency, rate, or extent of interleukin-21 production. go-plus.json regulation of IL-21 production|regulation of interleukin-21 biosynthetic process http://purl.obolibrary.org/obo/GO_0032665 GO:0017046 biolink:MolecularActivity peptide hormone binding Binding to a peptide with hormonal activity in animals. go-plus.json polypeptide hormone binding http://purl.obolibrary.org/obo/GO_0017046 CHEBI:3392 biolink:ChemicalSubstance carbendazim go-plus.json http://purl.obolibrary.org/obo/CHEBI_3392 chebi_ph7_3 GO:0032664 biolink:BiologicalProcess regulation of interleukin-20 production Any process that modulates the frequency, rate, or extent of interleukin-20 production. go-plus.json regulation of IL-20 production|regulation of interleukin-20 biosynthetic process http://purl.obolibrary.org/obo/GO_0032664 CHEBI:3391 biolink:ChemicalSubstance carbazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_3391 GO:0017045 biolink:MolecularActivity corticotropin-releasing hormone activity The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary. Wikipedia:Corticotropin-releasing_hormone go-plus.json adrenocorticotropin-releasing hormone http://purl.obolibrary.org/obo/GO_0017045 GO:0032663 biolink:BiologicalProcess regulation of interleukin-2 production Any process that modulates the frequency, rate, or extent of interleukin-2 production. go-plus.json regulation of interleukin-2 secretion|regulation of IL-2 production|regulation of interleukin-2 biosynthetic process http://purl.obolibrary.org/obo/GO_0032663 GO:0017048 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017048 GO:0017047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017047 GO:0032662 biolink:BiologicalProcess regulation of interleukin-19 production Any process that modulates the frequency, rate, or extent of interleukin-19 production. go-plus.json regulation of IL-19 production|regulation of interleukin-19 biosynthetic process http://purl.obolibrary.org/obo/GO_0032662 GO:0017042 biolink:MolecularActivity glycosylceramidase activity Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine. MetaCyc:GLYCOSYLCERAMIDASE-RXN|EC:3.2.1.62 go-plus.json phlorizin hydrolase activity|glycosyl-N-acylsphingosine glycohydrolase activity|phloridzin glucosidase activity|cerebrosidase activity|lactase-phlorizin hydrolase|phloridzin beta-glucosidase activity|glycosyl ceramide glycosylhydrolase activity|phloretin-glucosidase activity http://purl.obolibrary.org/obo/GO_0017042 GO:0032661 biolink:BiologicalProcess regulation of interleukin-18 production Any process that modulates the frequency, rate, or extent of interleukin-18 production. go-plus.json regulation of interleukin-18 biosynthetic process|regulation of IL-18 production|regulation of interleukin-18 secretion http://purl.obolibrary.org/obo/GO_0032661 GO:0032660 biolink:BiologicalProcess regulation of interleukin-17 production Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. go-plus.json regulation of CTLA-8 production|regulation of IL-17 production|regulation of interleukin-17 biosynthetic process|regulation of interleukin-17 secretion|regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion http://purl.obolibrary.org/obo/GO_0032660 GO:0017041 biolink:MolecularActivity galactosylgalactosylglucosylceramidase activity Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose. MetaCyc:3.2.1.47-RXN|EC:3.2.1.47|RHEA:21112 go-plus.json ceramidetrihexoside alpha-galactosidase activity|D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity|ceramide trihexosidase activity|ceramidetrihexosidase activity|trihexosylceramide alpha-galactosidase activity|trihexosyl ceramide galactosidase activity http://purl.obolibrary.org/obo/GO_0017041 GO:0017044 biolink:MolecularActivity melanocyte-stimulating hormone activity The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates. go-plus.json alpha-melanocyte stimulating hormone activity|alpha-melanophore stimulating hormone activity|melanocyte stimulating hormone activity http://purl.obolibrary.org/obo/GO_0017044 GO:0017043 biolink:MolecularActivity obsolete adrenocorticotropin OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones. go-plus.json corticotropin|adrenocorticotropin http://purl.obolibrary.org/obo/GO_0017043 CHEBI:176527 biolink:ChemicalSubstance (2S)-3-sulfopropanediol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176527 GO:0032659 biolink:BiologicalProcess regulation of interleukin-16 production Any process that modulates the frequency, rate, or extent of interleukin-16 production. go-plus.json regulation of IL-16 production|regulation of interleukin-16 biosynthetic process http://purl.obolibrary.org/obo/GO_0032659 GO:0032658 biolink:BiologicalProcess regulation of interleukin-15 production Any process that modulates the frequency, rate, or extent of interleukin-15 production. go-plus.json regulation of interleukin-15 biosynthetic process|regulation of IL-15 production http://purl.obolibrary.org/obo/GO_0032658 GO:0032657 biolink:BiologicalProcess regulation of interleukin-14 production Any process that modulates the frequency, rate, or extent of interleukin-14 production. go-plus.json regulation of IL-14 production|regulation of interleukin-14 biosynthetic process http://purl.obolibrary.org/obo/GO_0032657 GO:0032656 biolink:BiologicalProcess regulation of interleukin-13 production Any process that modulates the frequency, rate, or extent of interleukin-13 production. go-plus.json regulation of interleukin-13 secretion|regulation of IL-13 production|regulation of interleukin-13 biosynthetic process http://purl.obolibrary.org/obo/GO_0032656 GO:0032655 biolink:BiologicalProcess regulation of interleukin-12 production Any process that modulates the frequency, rate, or extent of interleukin-12 production. go-plus.json regulation of NKSF production|regulation of interleukin-12 secretion|regulation of CLMF production|regulation of interleukin-12 biosynthetic process|regulation of IL-12 production http://purl.obolibrary.org/obo/GO_0032655 GO:0042024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042024 GO:0042023 biolink:BiologicalProcess DNA endoreduplication Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes. go-plus.json DNA endoreplication|DNA re-duplication http://purl.obolibrary.org/obo/GO_0042023 GO:0042026 biolink:BiologicalProcess protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. go-plus.json heat shock protein activity http://purl.obolibrary.org/obo/GO_0042026 GO:0042025 biolink:CellularComponent host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0042025 GO:0042020 biolink:MolecularActivity interleukin-23 receptor activity Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json IL-23R|IL-23 receptor activity http://purl.obolibrary.org/obo/GO_0042020 GO:0042022 biolink:CellularComponent interleukin-12 receptor complex A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits. go-plus.json IL-12 receptor complex|IL12RB1-IL12RB2 complex http://purl.obolibrary.org/obo/GO_0042022 GO:0042021 biolink:MolecularActivity granulocyte macrophage colony-stimulating factor complex binding Binding to a granulocyte macrophage colony-stimulating factor complex. go-plus.json granulocyte macrophage colony stimulating factor complex binding|GM-CSF complex binding|GMC-SF complex binding http://purl.obolibrary.org/obo/GO_0042021 GO:0017017 biolink:MolecularActivity MAP kinase tyrosine/serine/threonine phosphatase activity Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate. go-plus.json dual-specificity MAP kinase phosphatase activity http://purl.obolibrary.org/obo/GO_0017017 GO:0042028 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042028 GO:0017016 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017016 GO:0042027 biolink:MolecularActivity obsolete cyclophilin-type peptidyl-prolyl cis-trans isomerase activity OBSOLETE. Catalysis of the reaction: peptidylproline (omega=180) = peptidylproline (omega=0). go-plus.json cyclophilin-type peptidyl-prolyl cis-trans isomerase activity http://purl.obolibrary.org/obo/GO_0042027 GO:0017019 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017019 GO:0042029 biolink:MolecularActivity obsolete fibrolase activity OBSOLETE. Catalysis of the cleavage of 14-Ala-Leu-15 in insulin B chain and cleavage of 413-Lys-Leu-414 in alpha chain of fibrinogen. go-plus.json fibrolase activity|fibrinolytic proteinase activity|Agkistrodon contortrix contortrix venom metalloproteinase activity|Agkistrodon contortrix contortrix metalloproteinase activity http://purl.obolibrary.org/obo/GO_0042029 GO:0017018 biolink:MolecularActivity myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. Reactome:R-HSA-390593|Reactome:R-HSA-445699 go-plus.json myosin phosphatase myosin binding|myosin phosphatase, intrinsic catalyst activity http://purl.obolibrary.org/obo/GO_0017018 GO:0032654 biolink:BiologicalProcess regulation of interleukin-11 production Any process that modulates the frequency, rate, or extent of interleukin-11 production. go-plus.json regulation of interleukin-11 secretion|regulation of IL-11 production|regulation of interleukin-11 biosynthetic process http://purl.obolibrary.org/obo/GO_0032654 GO:0017013 biolink:BiologicalProcess protein flavinylation The addition of a flavin group to a protein amino acid. go-plus.json protein amino acid flavinylation http://purl.obolibrary.org/obo/GO_0017013 GO:0017012 biolink:BiologicalProcess protein-phytochromobilin linkage The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin. RESID:AA0133 go-plus.json http://purl.obolibrary.org/obo/GO_0017012 GO:0032653 biolink:BiologicalProcess regulation of interleukin-10 production Any process that modulates the frequency, rate, or extent of interleukin-10 production. go-plus.json regulation of interleukin-10 secretion|regulation of interleukin-10 biosynthetic process|regulation of IL-10 production http://purl.obolibrary.org/obo/GO_0032653 GO:0017015 biolink:BiologicalProcess regulation of transforming growth factor beta receptor signaling pathway Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway. go-plus.json regulation of TGF-beta receptor signaling pathway|regulation of TGFbeta receptor signaling pathway|regulation of transforming growth factor beta receptor signalling pathway http://purl.obolibrary.org/obo/GO_0017015 GO:0032652 biolink:BiologicalProcess regulation of interleukin-1 production Any process that modulates the frequency, rate, or extent of interleukin-1 production. go-plus.json regulation of interleukin-1 biosynthetic process|regulation of IL-1 production|regulation of interleukin-1 secretion http://purl.obolibrary.org/obo/GO_0032652 GO:0017014 biolink:BiologicalProcess protein nitrosylation The covalent addition of a nitric oxide group to an amino acid within a protein. go-plus.json protein amino acid nitrosylation http://purl.obolibrary.org/obo/GO_0017014 GO:0032651 biolink:BiologicalProcess regulation of interleukin-1 beta production Any process that modulates the frequency, rate, or extent of interleukin-1 beta production. go-plus.json regulation of interleukin-1 beta secretion|regulation of interleukin-1 beta biosynthetic process|regulation of IL-1 beta production http://purl.obolibrary.org/obo/GO_0032651 GO:0032650 biolink:BiologicalProcess regulation of interleukin-1 alpha production Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production. go-plus.json regulation of interleukin-1 alpha biosynthetic process|regulation of IL-1 alpha production|regulation of interleukin-1 alpha secretion http://purl.obolibrary.org/obo/GO_0032650 CHEBI:3362 biolink:ChemicalSubstance canthaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3362 chebi_ph7_3 GO:0017011 biolink:BiologicalProcess protein-phycoerythrobilin linkage The linkage of the chromophore phycoerythrobilin to phycoerythrins. RESID:AA0132 go-plus.json http://purl.obolibrary.org/obo/GO_0017011 GO:0017010 biolink:BiologicalProcess protein-phycourobilin linkage The linkage of the chromophore phycourobilin to phycoerythrins. RESID:AA0260 go-plus.json http://purl.obolibrary.org/obo/GO_0017010 GO:0032649 biolink:BiologicalProcess regulation of interferon-gamma production Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. go-plus.json regulation of interferon-gamma biosynthetic process|regulation of type II interferon production|regulation of interferon-gamma secretion http://purl.obolibrary.org/obo/GO_0032649 GO:0032648 biolink:BiologicalProcess regulation of interferon-beta production Any process that modulates the frequency, rate, or extent of interferon-beta production. go-plus.json regulation of interferon-beta biosynthetic process|regulation of IFN-beta production|regulation of interferon-beta secretion http://purl.obolibrary.org/obo/GO_0032648 GO:0032647 biolink:BiologicalProcess regulation of interferon-alpha production Any process that modulates the frequency, rate, or extent of interferon-alpha production. go-plus.json regulation of interferon-alpha biosynthetic process|regulation of interferon-alpha secretion http://purl.obolibrary.org/obo/GO_0032647 GO:0032646 biolink:BiologicalProcess regulation of hepatocyte growth factor production Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production. go-plus.json regulation of hepatocyte growth factor biosynthetic process|regulation of HGF production|regulation of scatter factor production http://purl.obolibrary.org/obo/GO_0032646 GO:0032645 biolink:BiologicalProcess regulation of granulocyte macrophage colony-stimulating factor production Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. go-plus.json regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|regulation of GM-CSF production|regulation of granulocyte macrophage colony stimulating factor production http://purl.obolibrary.org/obo/GO_0032645 GO:0032644 biolink:BiologicalProcess regulation of fractalkine production Any process that modulates the frequency, rate, or extent of fractalkine production. go-plus.json regulation of CX3CL1 production|regulation of fractalkine biosynthetic process|regulation of CX3CL1 biosynthesis http://purl.obolibrary.org/obo/GO_0032644 GO:0042035 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042035 GO:0042034 biolink:BiologicalProcess peptidyl-L-lysine methyl ester biosynthetic process from peptidyl-lysine The modification of a C-terminal peptidyl-lysine to form peptidyl-L-lysine methyl ester. RESID:AA0318 go-plus.json peptidyl-lysine esterification http://purl.obolibrary.org/obo/GO_0042034 GO:0042037 biolink:BiologicalProcess peptidyl-histidine methylation, to form pros-methylhistidine The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine). RESID:AA0073 go-plus.json peptidyl-histidine pros-methylation http://purl.obolibrary.org/obo/GO_0042037 GO:0042036 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042036 GO:0042031 biolink:MolecularActivity obsolete angiotensin-converting enzyme inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of angiotensin-converting enzyme, thereby preventing the synthesis of angiotensin II from its precursor, angiotensin I. go-plus.json ACE inhibitor|peptidyl dipeptidase A inhibitor|angiotensin-converting enzyme inhibitor activity http://purl.obolibrary.org/obo/GO_0042031 GO:0042030 biolink:MolecularActivity ATPase inhibitor activity Binds to and stops, prevents or reduces an ATP hydrolysis activity. go-plus.json adenosinetriphosphatase inhibitor http://purl.obolibrary.org/obo/GO_0042030 GO:0042033 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042033 GO:0042032 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042032 CHEBI:3378 biolink:ChemicalSubstance capsorubin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3378 chebi_ph7_3 GO:0017028 biolink:MolecularActivity obsolete protein stabilization activity OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds. go-plus.json protein stabilization activity http://purl.obolibrary.org/obo/GO_0017028 GO:0042039 biolink:BiologicalProcess vanadium incorporation into metallo-sulfur cluster The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n). go-plus.json vanadium incorporation into metallo-sulphur cluster http://purl.obolibrary.org/obo/GO_0042039 GO:0017027 biolink:MolecularActivity obsolete transmembrane receptor protein serine/threonine kinase receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json transmembrane receptor protein serine/threonine kinase receptor-associated protein activity http://purl.obolibrary.org/obo/GO_0017027 GO:0042038 biolink:BiologicalProcess peptidyl-histidine methylation, to form tele-methylhistidine The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine). RESID:AA0317 go-plus.json peptidyl-histidine tele-methylation http://purl.obolibrary.org/obo/GO_0042038 GO:0017029 biolink:MolecularActivity obsolete lysosomal protein stabilization OBSOLETE. (Was not defined before being made obsolete). go-plus.json lysosomal protein stabilization http://purl.obolibrary.org/obo/GO_0017029 GO:0032643 biolink:BiologicalProcess regulation of connective tissue growth factor production Any process that modulates the frequency, rate, or extent of connective tissue growth factor production. go-plus.json regulation of hypertrophic chondrocyte-specific gene product 24 production|regulation of connective tissue growth factor biosynthetic process|regulation of Fisp12 production|regulation of IGFBP8 production|regulation of CCN2 production|regulation of CTGF production|regulation of Hcs24 production http://purl.obolibrary.org/obo/GO_0032643 GO:0017024 biolink:MolecularActivity myosin I binding Binding to a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments. go-plus.json http://purl.obolibrary.org/obo/GO_0017024 GO:0017023 biolink:CellularComponent myosin phosphatase complex An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin. go-plus.json http://purl.obolibrary.org/obo/GO_0017023 GO:0032642 biolink:BiologicalProcess regulation of chemokine production Any process that modulates the frequency, rate, or extent of chemokine production. go-plus.json regulation of chemokine secretion|regulation of chemokine biosynthetic process http://purl.obolibrary.org/obo/GO_0032642 GO:0017026 biolink:MolecularActivity obsolete procollagen C-endopeptidase activity OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III. go-plus.json BMP1|procollagen C-terminal peptidase activity|procollagen C-endopeptidase activity|carboxyprocollagen peptidase activity|procollagen peptidase activity|procollagen carboxy-terminal proteinase activity|procollagen C-proteinase activity|procollagen C-terminal proteinase activity|procollagen carboxypeptidase activity http://purl.obolibrary.org/obo/GO_0017026 GO:0032641 biolink:BiologicalProcess lymphotoxin A production The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A. go-plus.json TNF-beta production|lymphotoxin A biosynthetic process|tumor necrosis factor-beta production|lymphotoxin A synthesis|LTA production|lymphotoxin-alpha production|lymphotoxin A formation|TNF-B production http://purl.obolibrary.org/obo/GO_0032641 gocheck_do_not_annotate GO:0032640 biolink:BiologicalProcess tumor necrosis factor production The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. go-plus.json TNF alpha biosynthesis|tumor necrosis factor biosynthetic process|tumor necrosis factor secretion|tumor necrosis factor anabolism|tumor necrosis factor biosynthesis|TNF biosynthetic process|TNF biosynthesis|tumor necrosis factor synthesis|cachectin production|tumor necrosis factor formation|Tnfa production|tumor necrosis factor-alpha production|TNF-alpha production|TNF-alpha biosynthetic process|TNF-alpha biosynthesis|TNF production http://purl.obolibrary.org/obo/GO_0032640 gocheck_do_not_annotate GO:0017025 biolink:MolecularActivity TBP-class protein binding Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs). go-plus.json TBP binding|TBP-related factor (TRF) protein binding|TATA-binding protein binding http://purl.obolibrary.org/obo/GO_0017025 GO:0017020 biolink:MolecularActivity myosin phosphatase regulator activity Binds to and modulates of the activity of myosin phosphatase. go-plus.json myosin phosphatase, intrinsic regulator activity http://purl.obolibrary.org/obo/GO_0017020 GO:0017022 biolink:MolecularActivity myosin binding Binding to a myosin; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments. go-plus.json myosin phosphatase myosin binding http://purl.obolibrary.org/obo/GO_0017022 GO:0017021 biolink:MolecularActivity obsolete myosin phosphatase myosin binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json myosin phosphatase myosin binding http://purl.obolibrary.org/obo/GO_0017021 CHEBI:3375 biolink:ChemicalSubstance capsanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3375 chebi_ph7_3 GO:0032639 biolink:BiologicalProcess TRAIL production The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TRAIL biosynthetic process http://purl.obolibrary.org/obo/GO_0032639 gocheck_do_not_annotate GO:0042040 biolink:BiologicalProcess metal incorporation into metallo-molybdopterin complex The incorporation of a metal into a metallo-molybdopterin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0042040 GO:0032638 biolink:BiologicalProcess interleukin-9 production The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-9 secretion|interleukin-9 biosynthetic process|IL-9 production http://purl.obolibrary.org/obo/GO_0032638 gocheck_do_not_annotate GO:0032637 biolink:BiologicalProcess interleukin-8 production The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-8 secretion|interleukin-8 biosynthetic process|IL-8 production http://purl.obolibrary.org/obo/GO_0032637 gocheck_do_not_annotate GO:0032636 biolink:BiologicalProcess interleukin-7 production The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-7 biosynthetic process|interleukin-7 secretion|IL-7 production http://purl.obolibrary.org/obo/GO_0032636 gocheck_do_not_annotate GO:0032635 biolink:BiologicalProcess interleukin-6 production The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-6 biosynthetic process|interleukin-6 secretion|IL-6 production http://purl.obolibrary.org/obo/GO_0032635 gocheck_do_not_annotate GO:0032634 biolink:BiologicalProcess interleukin-5 production The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-5 biosynthetic process|interleukin-5 secretion|IL-5 production http://purl.obolibrary.org/obo/GO_0032634 gocheck_do_not_annotate GO:0032633 biolink:BiologicalProcess interleukin-4 production The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-4 biosynthetic process|interleukin-4 secretion|IL-4 production http://purl.obolibrary.org/obo/GO_0032633 gocheck_do_not_annotate GO:0042046 biolink:BiologicalProcess W-molybdopterin cofactor metabolic process The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands. go-plus.json Moco metabolism|W-molybdopterin cofactor metabolism|Moco metabolic process http://purl.obolibrary.org/obo/GO_0042046 GO:0042045 biolink:BiologicalProcess epithelial fluid transport The directed movement of fluid across epithelia. go-plus.json http://purl.obolibrary.org/obo/GO_0042045 GO:0042048 biolink:BiologicalProcess olfactory behavior The behavior of an organism in response to an odor. go-plus.json behavioral response to scent|behavioural response to smell|olfactory behaviour|behavioral response to smell|behavioural response to scent|behavioural response to odour http://purl.obolibrary.org/obo/GO_0042048 GO:0042047 biolink:BiologicalProcess W-molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands. go-plus.json W-molybdopterin cofactor synthesis|W-molybdopterin cofactor biosynthesis|W-molybdopterin cofactor formation|W-molybdopterin cofactor anabolism|Moco biosynthetic process|Moco biosynthesis http://purl.obolibrary.org/obo/GO_0042047 GO:0042042 biolink:BiologicalProcess tungsten incorporation into tungsten-molybdopterin complex The incorporation of tungsten into a tungsten-molybdopterin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0042042 GO:0042041 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042041 GO:0042044 biolink:BiologicalProcess fluid transport The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042044 goslim_pir GO:0042043 biolink:MolecularActivity neurexin family protein binding Binding to a neurexin, a synaptic cell surface protein related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals. go-plus.json neuroligin http://purl.obolibrary.org/obo/GO_0042043 GO:0042049 biolink:BiologicalProcess cellular acyl-CoA homeostasis Any process involved in the maintenance of an internal steady state of acyl-CoA within a cell or between a cell and its external environment. go-plus.json cell acyl-CoA homeostasis http://purl.obolibrary.org/obo/GO_0042049 GO:0032632 biolink:BiologicalProcess interleukin-3 production The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-3 biosynthetic process|interleukin-3 secretion|IL-3 production http://purl.obolibrary.org/obo/GO_0032632 gocheck_do_not_annotate GO:0032631 biolink:BiologicalProcess interleukin-27 production The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-27 synthesis|interleukin-27 formation|interleukin-27 biosynthetic process|IL-27 production|interleukin-27 secretion http://purl.obolibrary.org/obo/GO_0032631 gocheck_do_not_annotate GO:0032630 biolink:BiologicalProcess interleukin-26 production The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-26 synthesis|interleukin-26 formation|AK155 secretion|interleukin-26 biosynthetic process|interleukin-26 biosynthesis|IL-26 production|interleukin-26 anabolism|interleukin-26 secretion http://purl.obolibrary.org/obo/GO_0032630 gocheck_do_not_annotate UBERON:0006800 biolink:AnatomicalEntity anatomical line Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006800 GO:0032629 biolink:BiologicalProcess interleukin-25 production The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-25 biosynthetic process|interleukin-25 biosynthesis|IL-25 production|IL17E secretion|interleukin-25 secretion|interleukin-25 anabolism|IL-25 secretion|interleukin-25 synthesis|interleukin-25 formation http://purl.obolibrary.org/obo/GO_0032629 gocheck_do_not_annotate GO:0032628 biolink:BiologicalProcess interleukin-24 production The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-24 biosynthetic process|IL-24 production|ST16 production|MDA7 production|interleukin-24 secretion http://purl.obolibrary.org/obo/GO_0032628 gocheck_do_not_annotate GO:0032627 biolink:BiologicalProcess interleukin-23 production The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-23 production|interleukin-23 secretion|interleukin-23 biosynthetic process http://purl.obolibrary.org/obo/GO_0032627 gocheck_do_not_annotate GO:0042051 biolink:BiologicalProcess compound eye photoreceptor development The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure. go-plus.json adult eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042051 GO:0032626 biolink:BiologicalProcess interleukin-22 production The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-22 production|IL22 production|ZCYTO18 production|ILTIF production|interleukin-22 secretion|interleukin-22 biosynthetic process http://purl.obolibrary.org/obo/GO_0032626 gocheck_do_not_annotate GO:0042050 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042050 GO:0032625 biolink:BiologicalProcess interleukin-21 production The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-21 production|interleukin-21 secretion|interleukin-21 biosynthetic process http://purl.obolibrary.org/obo/GO_0032625 gocheck_do_not_annotate GO:0032624 biolink:BiologicalProcess interleukin-20 production The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IL-20 production|ZCYTO10 production|interleukin-20 secretion|interleukin-20 biosynthetic process http://purl.obolibrary.org/obo/GO_0032624 gocheck_do_not_annotate GO:0032623 biolink:BiologicalProcess interleukin-2 production The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-2 biosynthetic process|interleukin-2 secretion|IL-2 production http://purl.obolibrary.org/obo/GO_0032623 gocheck_do_not_annotate GO:0032622 biolink:BiologicalProcess interleukin-19 production The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json ZMDA1 secretion|interleukin-19 biosynthetic process|IL-19 production|interleukin-19 secretion|IL-19 secretion http://purl.obolibrary.org/obo/GO_0032622 gocheck_do_not_annotate CHEBI:127547 biolink:ChemicalSubstance 19-(4-hydroxyphenyl)nonadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_127547 GO:0042057 biolink:MolecularActivity obsolete transforming growth factor beta receptor anchoring activity OBSOLETE. Binds to transforming growth factor beta receptor and anchors it to a particular subcellular location. go-plus.json transforming growth factor beta receptor anchoring activity|TGF-beta receptor anchoring activity|TGFbeta receptor anchoring activity|transforming growth factor beta receptor anchor activity http://purl.obolibrary.org/obo/GO_0042057 GO:0042056 biolink:MolecularActivity chemoattractant activity Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal. go-plus.json attractant http://purl.obolibrary.org/obo/GO_0042056 goslim_chembl|goslim_pir GO:0042059 biolink:BiologicalProcess negative regulation of epidermal growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. go-plus.json negative regulation of EGF receptor signaling pathway|negative regulation of EGF receptor signalling pathway|down-regulation of epidermal growth factor receptor signaling pathway|negative regulation of EGFR signaling pathway|downregulation of epidermal growth factor receptor signaling pathway|down regulation of epidermal growth factor receptor signaling pathway|inhibition of epidermal growth factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_0042059 GO:0042058 biolink:BiologicalProcess regulation of epidermal growth factor receptor signaling pathway Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. go-plus.json regulation of EGF receptor signalling pathway|regulation of EGF receptor signaling pathway|regulation of EGFR signaling pathway http://purl.obolibrary.org/obo/GO_0042058 GO:0042053 biolink:BiologicalProcess regulation of dopamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. go-plus.json regulation of dopamine metabolism http://purl.obolibrary.org/obo/GO_0042053 GO:0042052 biolink:BiologicalProcess rhabdomere development The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments. go-plus.json rhabdomere organization http://purl.obolibrary.org/obo/GO_0042052 GO:0042055 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042055 GO:0042054 biolink:MolecularActivity histone methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue. EC:2.1.1.354 go-plus.json histone methylase activity http://purl.obolibrary.org/obo/GO_0042054 GO:0017009 biolink:BiologicalProcess protein-phycocyanobilin linkage The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin. RESID:AA0131 go-plus.json http://purl.obolibrary.org/obo/GO_0017009 GO:0017006 biolink:BiologicalProcess protein-tetrapyrrole linkage The covalent linking of a tetrapyrrole to a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0017006 GO:0017005 biolink:MolecularActivity 3'-tyrosyl-DNA phosphodiesterase activity Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0017005 GO:0017008 biolink:BiologicalProcess protein-phycobiliviolin linkage The linkage of the chromophore phycobiliviolin to phycoerythrocyanin. RESID:AA0258 go-plus.json http://purl.obolibrary.org/obo/GO_0017008 GO:0017007 biolink:BiologicalProcess protein-bilin linkage The covalent linkage of bilin and a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0017007 GO:0032621 biolink:BiologicalProcess interleukin-18 production The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IGIF production|interleukin-18 biosynthetic process|IL-18 production|interleukin-18 secretion|IL1F4 production http://purl.obolibrary.org/obo/GO_0032621 gocheck_do_not_annotate GO:0017002 biolink:MolecularActivity activin-activated receptor activity Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta. go-plus.json activin receptor activity http://purl.obolibrary.org/obo/GO_0017002 GO:0032620 biolink:BiologicalProcess interleukin-17 production The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-17 biosynthetic process|IL-17 production|Cytotoxic T-lymphocyte-associated antigen 8 production|interleukin-17 secretion|CTLA-8 production http://purl.obolibrary.org/obo/GO_0032620 gocheck_do_not_annotate GO:0017001 biolink:BiologicalProcess antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. go-plus.json antibiotic degradation|antibiotic breakdown|antibiotic catabolism http://purl.obolibrary.org/obo/GO_0017001 GO:0017004 biolink:BiologicalProcess cytochrome complex assembly The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. go-plus.json cytochrome biogenesis http://purl.obolibrary.org/obo/GO_0017004 goslim_metagenomics GO:0017003 biolink:BiologicalProcess protein-heme linkage The covalent linkage of heme and a protein. go-plus.json protein-haem linkage http://purl.obolibrary.org/obo/GO_0017003 CHEBI:176557 biolink:ChemicalSubstance oxidized N-(fatty acyl)-L-alaninate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176557 CHEBI:176556 biolink:ChemicalSubstance N-(fatty acyl)-L-alaninate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176556 GO:0017000 biolink:BiologicalProcess antibiotic biosynthetic process The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. go-plus.json antibiotic biosynthesis|antibiotic anabolism|antibiotic synthesis|antibiotic formation http://purl.obolibrary.org/obo/GO_0017000 goslim_metagenomics GO:0042060 biolink:BiologicalProcess wound healing The series of events that restore integrity to a damaged tissue, following an injury. Wikipedia:Wound_healing go-plus.json http://purl.obolibrary.org/obo/GO_0042060 GO:0032618 biolink:BiologicalProcess interleukin-15 production The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-15 secretion|interleukin-15 biosynthetic process|IL-15 production http://purl.obolibrary.org/obo/GO_0032618 gocheck_do_not_annotate GO:0032617 biolink:BiologicalProcess interleukin-14 production The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-14 secretion|interleukin-14 biosynthetic process|IL-14 production http://purl.obolibrary.org/obo/GO_0032617 gocheck_do_not_annotate GO:0032616 biolink:BiologicalProcess interleukin-13 production The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-13 secretion|interleukin-13 biosynthetic process|IL-13 production http://purl.obolibrary.org/obo/GO_0032616 gocheck_do_not_annotate GO:0042062 biolink:BiologicalProcess long-term strengthening of neuromuscular junction Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0042062 GO:0032615 biolink:BiologicalProcess interleukin-12 production The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json NKSF production|interleukin-12 secretion|interleukin-12 biosynthetic process|IL-12 production|CLMF production http://purl.obolibrary.org/obo/GO_0032615 gocheck_do_not_annotate GO:0042061 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042061 GO:0032614 biolink:BiologicalProcess interleukin-11 production The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-11 secretion|interleukin-11 biosynthetic process|IL-11 production http://purl.obolibrary.org/obo/GO_0032614 gocheck_do_not_annotate GO:0032613 biolink:BiologicalProcess interleukin-10 production The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-10 secretion|interleukin-10 biosynthetic process|IL-10 production http://purl.obolibrary.org/obo/GO_0032613 gocheck_do_not_annotate GO:0032612 biolink:BiologicalProcess interleukin-1 production The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-1 biosynthetic process|interleukin-1 secretion|IL-1 production http://purl.obolibrary.org/obo/GO_0032612 gocheck_do_not_annotate GO:0032611 biolink:BiologicalProcess interleukin-1 beta production The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-1 beta secretion|interleukin-1 beta biosynthetic process|IL-1 beta production http://purl.obolibrary.org/obo/GO_0032611 gocheck_do_not_annotate GO:0042068 biolink:BiologicalProcess regulation of pteridine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine. go-plus.json regulation of pteridine metabolism http://purl.obolibrary.org/obo/GO_0042068 GO:0042067 biolink:BiologicalProcess establishment of ommatidial planar polarity The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part. go-plus.json establishment of ommatidial polarity http://purl.obolibrary.org/obo/GO_0042067 GO:0042069 biolink:BiologicalProcess regulation of catecholamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. go-plus.json regulation of catecholamine metabolism http://purl.obolibrary.org/obo/GO_0042069 GO:0042064 biolink:MolecularActivity obsolete cell adhesion receptor regulator activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json cell adhesion receptor regulator activity http://purl.obolibrary.org/obo/GO_0042064 CHEBI:45487 biolink:ChemicalSubstance 13-cis-retinal go-plus.json http://purl.obolibrary.org/obo/CHEBI_45487 chebi_ph7_3 GO:0042063 biolink:BiologicalProcess gliogenesis The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. go-plus.json glial cell generation http://purl.obolibrary.org/obo/GO_0042063 GO:0042066 biolink:BiologicalProcess perineurial glial growth Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons. go-plus.json http://purl.obolibrary.org/obo/GO_0042066 GO:0032619 biolink:BiologicalProcess interleukin-16 production The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json LCF production|interleukin-16 secretion|interleukin-16 biosynthetic process|IL-16 production|pro-interleukin-16 production http://purl.obolibrary.org/obo/GO_0032619 gocheck_do_not_annotate GO:0042065 biolink:BiologicalProcess glial cell growth Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0042065 GO:0032610 biolink:BiologicalProcess interleukin-1 alpha production The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-1 alpha biosynthetic process|IL-1 alpha production|interleukin-1 alpha secretion http://purl.obolibrary.org/obo/GO_0032610 gocheck_do_not_annotate CHEBI:176568 biolink:ChemicalSubstance oxidized N-(fatty acyl)-gamma-aminobutyrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176568 GO:0032607 biolink:BiologicalProcess interferon-alpha production The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IFN-alpha production|interferon-alpha biosynthetic process|IFNA production|interferon-alpha secretion http://purl.obolibrary.org/obo/GO_0032607 gocheck_do_not_annotate GO:0042071 biolink:MolecularActivity leucokinin receptor activity Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0042071 GO:0042070 biolink:BiologicalProcess maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster. go-plus.json oocyte axis determination, maintenance of oocyte nucleus position|maintenance of oocyte nucleus location involved in oocyte dorsal-ventral axis specification|oocyte axis determination, oocyte nucleus anchoring|oocyte nucleus anchoring during oocyte axis determination|maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis determination|oocyte axis determination, maintenance of oocyte nucleus localization|maintenance of oocyte nucleus location involved in oocyte dorsoventral axis specification|maintenance of oocyte nucleus position during oocyte axis determination|maintenance of oocyte nucleus localization during oocyte axis determination http://purl.obolibrary.org/obo/GO_0042070 GO:0032606 biolink:BiologicalProcess type I interferon production The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json type I interferon secretion|interferon type I production|type I IFN production|type I interferon biosynthetic process http://purl.obolibrary.org/obo/GO_0032606 gocheck_do_not_annotate GO:0042073 biolink:BiologicalProcess intraciliary transport The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. Wikipedia:Intraflagellar_transport go-plus.json intraflagellar transport|IFT|intraflagellar transport involved in cilium organization|intraflagellar transport involved in microtubule-based flagellum organisation http://purl.obolibrary.org/obo/GO_0042073 GO:0032605 biolink:BiologicalProcess hepatocyte growth factor production The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json HGF production|scatter factor production|hepatocyte growth factor biosynthetic process http://purl.obolibrary.org/obo/GO_0032605 gocheck_do_not_annotate GO:0032604 biolink:BiologicalProcess granulocyte macrophage colony-stimulating factor production The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json granulocyte macrophage colony-stimulating factor biosynthetic process|GM-CSF production|granulocyte macrophage colony stimulating factor production http://purl.obolibrary.org/obo/GO_0032604 gocheck_do_not_annotate GO:0042072 biolink:MolecularActivity obsolete cell adhesion receptor inhibitor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json cell adhesion receptor inhibitor activity http://purl.obolibrary.org/obo/GO_0042072 GO:0032603 biolink:BiologicalProcess fractalkine production The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json ABCD-3 production|CX3CL1 production|fractalkine metabolic process|fractalkine biosynthetic process|neurotactin production http://purl.obolibrary.org/obo/GO_0032603 gocheck_do_not_annotate GO:0032602 biolink:BiologicalProcess chemokine production The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. go-plus.json chemokine anabolism|chemokine synthesis|chemokine formation|chemokine metabolic process|chemokine biosynthetic process|chemokine secretion|chemokine biosynthesis http://purl.obolibrary.org/obo/GO_0032602 gocheck_do_not_annotate GO:0032601 biolink:BiologicalProcess connective tissue growth factor production The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CTGF production|Hcs24 production|Fisp12 production|hypertrophic chondrocyte-specific gene product 24 production|IGFBP8 production|CCN2 production http://purl.obolibrary.org/obo/GO_0032601 gocheck_do_not_annotate GO:0032600 biolink:BiologicalProcess chemokine receptor transport out of membrane raft The directed movement of a chemokine receptor out of a membrane raft. go-plus.json chemokine receptor translocation out of membrane raft|chemokine receptor transport out of lipid raft http://purl.obolibrary.org/obo/GO_0032600 GO:0042079 biolink:BiologicalProcess obsolete GPI/GSI anchor metabolic process OBSOLETE. (Was not defined before being made obsolete). go-plus.json GPI/GSI anchor metabolic process http://purl.obolibrary.org/obo/GO_0042079 GO:0042078 biolink:BiologicalProcess germ-line stem cell division The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. go-plus.json germ-line stem cell renewal http://purl.obolibrary.org/obo/GO_0042078 CHEBI:45479 biolink:ChemicalSubstance 13-cis-retinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_45479 chebi_ph7_3 GO:0042075 biolink:BiologicalProcess nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase. RESID:AA0310 go-plus.json nickel incorporation into nickel-iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide http://purl.obolibrary.org/obo/GO_0042075 GO:0042074 biolink:BiologicalProcess cell migration involved in gastrulation The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). go-plus.json http://purl.obolibrary.org/obo/GO_0042074 GO:0042077 biolink:BiologicalProcess protein phosphate-linked glycosylation via serine The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues. go-plus.json protein amino acid phosphate-linked glycosylation via serine http://purl.obolibrary.org/obo/GO_0042077 GO:0032609 biolink:BiologicalProcess interferon-gamma production The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon. go-plus.json type II IFN production|interferon-gamma secretion|interferon-gamma biosynthetic process|IFNG production|type II interferon production http://purl.obolibrary.org/obo/GO_0032609 gocheck_do_not_annotate GO:0032608 biolink:BiologicalProcess interferon-beta production The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json IFN-beta production|interferon-beta biosynthetic process|interferon-beta secretion|IFNB production http://purl.obolibrary.org/obo/GO_0032608 gocheck_do_not_annotate GO:0042076 biolink:BiologicalProcess protein phosphate-linked glycosylation The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues. go-plus.json phosphoglycosylation|protein amino acid phosphate-linked glycosylation http://purl.obolibrary.org/obo/GO_0042076 GO:0140507 biolink:BiologicalProcess granzyme-mediated programmed cell death signaling pathway A series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells. go-plus.json granzyme-mediated cell death signaling pathway http://purl.obolibrary.org/obo/GO_0140507 GO:0140509 biolink:BiologicalProcess epithelium-like organization The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins. go-plus.json http://purl.obolibrary.org/obo/GO_0140509 GO:0140500 biolink:BiologicalProcess regulation of reticulophagy Any process that modulates the frequency, rate or extent of reticulophagy. go-plus.json regulation of ER-phagy|regulation of ER autophagy|regulation of endoplasmic reticulum autophagy|regulation of ER degradation|regulation of autophagy of the ER|regulation of autophagy of the endoplasmic reticulum|regulation of endoplasmic reticulum degradation http://purl.obolibrary.org/obo/GO_0140500 GO:0140502 biolink:BiologicalProcess effector-mediated suppression of host salicylic acid-mediated innate immune signalling A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signalling. go-plus.json http://purl.obolibrary.org/obo/GO_0140502 GO:0140501 biolink:BiologicalProcess positive regulation of reticulophagy Any process that increases the frequency, rate or extent of reticulophagy. go-plus.json positive regulation of autophagy of the ER|positive regulation of endoplasmic reticulum degradation|positive regulation of ER-phagy|positive regulation of ER autophagy|positive regulation of ER degradation|positive regulation of autophagy of the endoplasmic reticulum|positive regulation of endoplasmic reticulum autophagy http://purl.obolibrary.org/obo/GO_0140501 GO:0140504 biolink:BiologicalProcess microlipophagy Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination. go-plus.json lipid droplet autophagy http://purl.obolibrary.org/obo/GO_0140504 GO:0140506 biolink:MolecularActivity endoplasmic reticulum-autophagosome adaptor activity The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy. go-plus.json autophagosome-ER anchor|ER- autophagosome anchor|autophagosome-endoplasmic reticulum anchor http://purl.obolibrary.org/obo/GO_0140506 GO:0140505 biolink:BiologicalProcess regulation of microlipophagy Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion. go-plus.json http://purl.obolibrary.org/obo/GO_0140505 GO:0140529 biolink:BiologicalProcess CMG complex assembly The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0140529 GO:0140522 biolink:MolecularActivity fusogenic activity The activity of joining two lipid bilayers to form a single membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140522 GO:0140523 biolink:MolecularActivity GTPase-dependent fusogenic activity A GTPase activity that mediates the joining two lipid bilayers to form a single membrane. go-plus.json membrane fusion GTPase activity http://purl.obolibrary.org/obo/GO_0140523 GO:0140526 biolink:BiologicalProcess double membrane vesicle viral factory assembly A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0140526 GO:0140525 biolink:CellularComponent antipodal site The pole of the kinetoplast associated with kinetoplast DNA replication. The antipodal sites flank the kinetoplast DNA disk and are positioned approximately 180 degrees apart. In Trypanosoma brucei and Crithidia fasciculata, minicircles are attached at antipodal sites and they contain enzymes that catalyse some of the later reactions in minicircle replication. go-plus.json antipodal zone http://purl.obolibrary.org/obo/GO_0140525 GO:0140528 biolink:BiologicalProcess bilobe structure assembly The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone). go-plus.json bilobe structure formation|kinetoplastid flagellar hook complex assembly|bilobe structure biogenesis http://purl.obolibrary.org/obo/GO_0140528 GO:0140527 biolink:BiologicalProcess reciprocal homologous recombination A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0140527 GO:0017097 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017097 GO:0017096 biolink:MolecularActivity acetylserotonin O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine. MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN|RHEA:15573|EC:2.1.1.4 go-plus.json S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity|acetylserotonin methyltransferase activity|N-acetylserotonin O-methyltransferase activity|hydroxyindole methyltransferase activity|hydroxyindole O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0017096 GO:0017099 biolink:MolecularActivity very-long-chain-acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. Reactome:R-HSA-548831 go-plus.json very long-chain-acyl-CoA dehydrogenase activity http://purl.obolibrary.org/obo/GO_0017099 GO:0017098 biolink:MolecularActivity sulfonylurea receptor binding Binding to a sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel. go-plus.json sulphonylurea receptor binding|sulfonylurea receptor ligand http://purl.obolibrary.org/obo/GO_0017098 OBO:GOCHE_24527 biolink:OntologyClass substance with herbicide role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24527 3_STAR GO:0140511 biolink:CellularComponent mitotic nuclear bridge stalk Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0140511 GO:0140510 biolink:CellularComponent mitotic nuclear bridge A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei. go-plus.json nuclear bridge http://purl.obolibrary.org/obo/GO_0140510 GO:0140513 biolink:CellularComponent nuclear protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. go-plus.json nuclear complex http://purl.obolibrary.org/obo/GO_0140513 gocheck_do_not_annotate GO:0140512 biolink:CellularComponent mitotic nuclear bridge midzone The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei. go-plus.json http://purl.obolibrary.org/obo/GO_0140512 GO:0140515 biolink:BiologicalProcess mitotic nuclear bridge organization A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0140515 GO:0140517 biolink:MolecularActivity protein-RNA adaptor activity The binding activity of a protein that brings together another protein and an RNA, permitting those molecules to function in a coordinated way. go-plus.json http://purl.obolibrary.org/obo/GO_0140517 GO:0140516 biolink:BiologicalProcess mitotic nuclear pore complex disassembly The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis. go-plus.json nuclear pore complex disassembly during mitosis http://purl.obolibrary.org/obo/GO_0140516 GO:0017082 biolink:MolecularActivity obsolete mineralocorticoid receptor activity OBSOLETE. Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by binding to a specific DNA sequence in order to modulate transcription by RNA polymerase II. go-plus.json aldosterone receptor http://purl.obolibrary.org/obo/GO_0017082 PR:000021999 biolink:Protein death receptor A protein that contains multiple TNFR/NGFR cysteine-rich region (Pfam:PF00020) within the extracellular ligand-binding domain, a type I (single pass) transmembrane domain, and a cytoplasmic Death domain (Pfam:PF00531) required for intracellular signaling. go-plus.json http://purl.obolibrary.org/obo/PR_000021999 PR:000021998 biolink:Protein neurotrophin A protein that is a neurotrophic polypeptide factor that regulates neuronal differentiation and is essential for neuronal survival, neurite growth and plasticity. It contains a signal peptide, a propeptide, and a C-terminal Nerve growth factor family (Pfam:PF00243) domain. go-plus.json http://purl.obolibrary.org/obo/PR_000021998 GO:0017081 biolink:MolecularActivity chloride channel regulator activity Binds to and modulates the activity of a chloride channel. Reactome:R-HSA-383190 go-plus.json http://purl.obolibrary.org/obo/GO_0017081 GO:0017084 biolink:MolecularActivity delta1-pyrroline-5-carboxylate synthetase activity Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate. Reactome:R-HSA-508040|RHEA:33207 go-plus.json D1-pyrroline-5-carboxylate synthetase activity http://purl.obolibrary.org/obo/GO_0017084 GO:0017083 biolink:MolecularActivity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R. EC:2.4.1.152|MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN|RHEA:14257 go-plus.json plasma alpha-3-fucosyltransferase activity|GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|galactoside 3-L-fucosyltransferase activity|Lewis-negative alpha-3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity|lewis-negative alpha-3-fucosyltransferase activity|galactoside 3-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0017083 GO:0017080 biolink:MolecularActivity sodium channel regulator activity Binds to and modulates the activity of a sodium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0017080 GO:0017079 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017079 GO:0017078 biolink:MolecularActivity obsolete Hsc70 protein regulator activity OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsc70. go-plus.json Hsc70 interacting protein|Hsc70 protein regulator activity http://purl.obolibrary.org/obo/GO_0017078 GO:0017075 biolink:MolecularActivity syntaxin-1 binding Binding to a syntaxin-1 SNAP receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0017075 GO:0017074 biolink:MolecularActivity obsolete procollagen N-endopeptidase activity OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln. go-plus.json procollagen aminoterminal protease activity|procollagen aminopeptidase activity|type I/II procollagen N-proteinase activity|procollagen N-terminal proteinase activity|aminoterminal procollagen peptidase activity|type III procollagen|procollagen N-proteinase activity|aminoprocollagen peptidase activity|procollagen N-endopeptidase activity|procollagen N-terminal peptidase activity http://purl.obolibrary.org/obo/GO_0017074 GO:0017077 biolink:MolecularActivity oxidative phosphorylation uncoupler activity Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. go-plus.json mitochondrial uncoupling protein activity|uncoupling protein activity http://purl.obolibrary.org/obo/GO_0017077 GO:0017076 biolink:MolecularActivity purine nucleotide binding Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0017076 GO:0017093 biolink:MolecularActivity obsolete sterol regulatory element-binding protein protease activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes. go-plus.json SREBP protease activity|sterol regulatory element-binding protein protease activity http://purl.obolibrary.org/obo/GO_0017093 GO:0017092 biolink:MolecularActivity obsolete sterol regulatory element-binding protein site 2 protease activity OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus. go-plus.json sterol regulatory element-binding protein site 2 protease activity|SREBP site 2 protease activity http://purl.obolibrary.org/obo/GO_0017092 GO:0017095 biolink:MolecularActivity heparan sulfate 6-O-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate. EC:2.8.2.-|Reactome:R-HSA-2076419 go-plus.json heparin 6-O-sulfotransferase activity|heparan sulphate 6-O-sulphotransferase activity http://purl.obolibrary.org/obo/GO_0017095 GO:0017094 biolink:MolecularActivity obsolete sterol regulatory element-binding protein site 1 protease activity OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves. go-plus.json sterol regulatory element-binding protein site 1 protease activity|SREBP site 1 protease activity http://purl.obolibrary.org/obo/GO_0017094 GO:0017091 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017091 GO:0017090 biolink:CellularComponent meprin A complex A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues. go-plus.json PABA peptide hydrolase complex http://purl.obolibrary.org/obo/GO_0017090 GO:0017089 biolink:MolecularActivity glycolipid transfer activity Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid. Reactome:R-HSA-9697077|Reactome:R-HSA-5340320 go-plus.json glycolipid transporter activity|intermembrane glycolipid transporter activity|glycolipid carrier activity|intermembrane glycolipid transfer activity http://purl.obolibrary.org/obo/GO_0017089 GO:0017086 biolink:CellularComponent 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate. go-plus.json BCADH|branched-chain alpha-ketoacid dehydrogenase complex http://purl.obolibrary.org/obo/GO_0017086 GO:0017085 biolink:BiologicalProcess response to insecticide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects. go-plus.json insecticide susceptibility/resistance|insecticide resistance http://purl.obolibrary.org/obo/GO_0017085 GO:0017088 biolink:MolecularActivity obsolete X-Pro dipeptidyl-peptidase activity OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile. go-plus.json X-prolyl dipeptidyl aminopeptidase activity|X-prolyl dipeptidyl peptidase activity|PepX|Xaa-Pro dipeptidyl-peptidase activity|X-Pro dipeptidyl-peptidase activity http://purl.obolibrary.org/obo/GO_0017088 GO:0017087 biolink:CellularComponent mitochondrial processing peptidase complex A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0017087 GO:0017060 biolink:MolecularActivity 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R. MetaCyc:2.4.1.65-RXN|Reactome:R-HSA-9603986|Reactome:R-HSA-5693925|RHEA:23628|EC:2.4.1.65 go-plus.json alpha-(1,4)-L-fucosyltransferase activity|beta-acetylglucosaminylsaccharide fucosyltransferase activity|blood group Lewis alpha-4-fucosyltransferase activity|Lewis blood group alpha-(1,3/4)-fucosyltransferase activity|Lewis FT activity|alpha-(1,3/1,4) fucosyltransferase III activity|alpha-4-L-fucosyltransferase activity|(Lea)-dependent (alpha-3/4)-fucosyltransferase activity|blood-group substance Lea-dependent fucosyltransferase|galactoside 3(4)-L-fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity|alpha-(1->4)-L-fucosyltransferase activity|FucT-II activity|3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity|guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity|Lewis blood group alpha-(1->3/4)-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity|alpha(1,4)-L-fucosyltransferase activity|GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity|blood-group substance Le(a)-dependent fucosyltransferase activity|Lewis alpha-(1->3/4)-fucosyltransferase activity|Lewis alpha-(1,3/4)-fucosyltransferase activity|GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0017060 GO:0017062 biolink:BiologicalProcess respiratory chain complex III assembly The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents. go-plus.json complex III biogenesis|cytochrome bc(1) complex biogenesis|coenzyme Q and cytochrome c reductase complex assembly|coenzyme Q and cytochrome c reductase complex biogenesis|cytochrome bc(1) complex assembly|complex III assembly http://purl.obolibrary.org/obo/GO_0017062 GO:0017061 biolink:MolecularActivity S-methyl-5-thioadenosine phosphorylase activity Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate. MetaCyc:5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN|EC:2.4.2.28|RHEA:11852|Reactome:R-HSA-1237160 go-plus.json methylthioadenosine phosphorylase activity|5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity|methylthioadenosine nucleoside phosphorylase activity|MTA phosphorylase activity|S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity|MeSAdo/Ado phosphorylase activity|MeSAdo phosphorylase activity|MTAPase activity|5'-deoxy-5'-methylthioadenosine phosphorylase activity|5'-methylthioadenosine phosphorylase activity http://purl.obolibrary.org/obo/GO_0017061 GO:0032699 biolink:BiologicalProcess negative regulation of interleukin-16 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production. go-plus.json inhibition of interleukin-16 production|negative regulation of interleukin-16 biosynthetic process|negative regulation of IL-16 production|down regulation of interleukin-16 production|downregulation of interleukin-16 production|down-regulation of interleukin-16 production http://purl.obolibrary.org/obo/GO_0032699 GO:0032690 biolink:BiologicalProcess negative regulation of interleukin-1 alpha production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production. go-plus.json negative regulation of interleukin-1 alpha secretion|down-regulation of interleukin-1 alpha production|negative regulation of interleukin-1 alpha biosynthetic process|downregulation of interleukin-1 alpha production|down regulation of interleukin-1 alpha production|inhibition of interleukin-1 alpha production|negative regulation of IL-1 alpha production http://purl.obolibrary.org/obo/GO_0032690 GO:0017057 biolink:MolecularActivity 6-phosphogluconolactonase activity Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+). Reactome:R-HSA-71296|MetaCyc:6PGLUCONOLACT-RXN|EC:3.1.1.31|RHEA:12556|KEGG_REACTION:R02035 go-plus.json 6-PGL|6-phospho-D-glucono-1,5-lactone lactonohydrolase activity|phosphogluconolactonase activity http://purl.obolibrary.org/obo/GO_0017057 GO:0032698 biolink:BiologicalProcess negative regulation of interleukin-15 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production. go-plus.json inhibition of interleukin-15 production|negative regulation of interleukin-15 biosynthetic process|negative regulation of IL-15 production|down regulation of interleukin-15 production|downregulation of interleukin-15 production|down-regulation of interleukin-15 production http://purl.obolibrary.org/obo/GO_0032698 GO:0032697 biolink:BiologicalProcess negative regulation of interleukin-14 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production. go-plus.json inhibition of interleukin-14 production|negative regulation of interleukin-14 biosynthetic process|negative regulation of IL-14 production|down regulation of interleukin-14 production|downregulation of interleukin-14 production|down-regulation of interleukin-14 production http://purl.obolibrary.org/obo/GO_0032697 GO:0017056 biolink:MolecularActivity structural constituent of nuclear pore The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules. Reactome:R-HSA-6783483|Reactome:R-HSA-1176059|Reactome:R-HSA-5252041|Reactome:R-HSA-5578744|Reactome:R-HSA-170796|Reactome:R-HSA-5661474|Reactome:R-HSA-192925|Reactome:R-HSA-192627 go-plus.json nucleocytoplasmic transporter activity|nuclear pore activity http://purl.obolibrary.org/obo/GO_0017056 GO:0032696 biolink:BiologicalProcess negative regulation of interleukin-13 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production. go-plus.json negative regulation of interleukin-13 biosynthetic process|negative regulation of IL-13 production|down regulation of interleukin-13 production|downregulation of interleukin-13 production|down-regulation of interleukin-13 production|negative regulation of interleukin-13 secretion|inhibition of interleukin-13 production http://purl.obolibrary.org/obo/GO_0032696 GO:0017059 biolink:CellularComponent serine C-palmitoyltransferase complex An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine. go-plus.json http://purl.obolibrary.org/obo/GO_0017059 GO:0032695 biolink:BiologicalProcess negative regulation of interleukin-12 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production. go-plus.json negative regulation of IL-12 production|down regulation of interleukin-12 production|negative regulation of NKSF production|downregulation of interleukin-12 production|down-regulation of interleukin-12 production|negative regulation of interleukin-12 secretion|negative regulation of CLMF production|inhibition of interleukin-12 production|negative regulation of interleukin-12 biosynthetic process http://purl.obolibrary.org/obo/GO_0032695 GO:0017058 biolink:MolecularActivity FH1 domain binding Binding to a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain. go-plus.json http://purl.obolibrary.org/obo/GO_0017058 GO:0032694 biolink:BiologicalProcess negative regulation of interleukin-11 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production. go-plus.json negative regulation of IL-11 production|down regulation of interleukin-11 production|downregulation of interleukin-11 production|down-regulation of interleukin-11 production|negative regulation of interleukin-11 secretion|inhibition of interleukin-11 production|negative regulation of interleukin-11 biosynthetic process http://purl.obolibrary.org/obo/GO_0032694 GO:0017053 biolink:CellularComponent transcription repressor complex A protein complex that possesses activity that prevents or downregulates transcription. go-plus.json cytoplasmic transcriptional repressor complex|nuclear transcriptional repressor complex|transcription factor inhibitor complex|transcriptional repressor complex http://purl.obolibrary.org/obo/GO_0017053 goslim_pir GO:0017052 biolink:CellularComponent obsolete insulin-like growth factor binding protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json insulin-like growth factor binding protein http://purl.obolibrary.org/obo/GO_0017052 GO:0032693 biolink:BiologicalProcess negative regulation of interleukin-10 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. go-plus.json negative regulation of IL-10 production|down regulation of interleukin-10 production|downregulation of interleukin-10 production|down-regulation of interleukin-10 production|inhibition of interleukin-10 production|negative regulation of interleukin-10 biosynthetic process|negative regulation of interleukin-10 secretion http://purl.obolibrary.org/obo/GO_0032693 GO:0017055 biolink:BiologicalProcess negative regulation of RNA polymerase II transcription preinitiation complex assembly Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. go-plus.json down-regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|negative regulation of RNA polymerase II transcriptional pre-initiation complex assembly|downregulation of RNA polymerase II transcriptional preinitiation complex assembly|down regulation of RNA polymerase II transcriptional preinitiation complex assembly|inhibition of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex formation http://purl.obolibrary.org/obo/GO_0017055 GO:0032692 biolink:BiologicalProcess negative regulation of interleukin-1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. go-plus.json down-regulation of interleukin-1 production|negative regulation of interleukin-1 biosynthetic process|downregulation of interleukin-1 production|down regulation of interleukin-1 production|inhibition of interleukin-1 production|negative regulation of IL-1 production|negative regulation of interleukin-1 secretion http://purl.obolibrary.org/obo/GO_0032692 GO:0032691 biolink:BiologicalProcess negative regulation of interleukin-1 beta production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. go-plus.json negative regulation of IL-1 beta production|down regulation of interleukin-1 beta production|downregulation of interleukin-1 beta production|down-regulation of interleukin-1 beta production|inhibition of interleukin-1 beta production|negative regulation of interleukin-1 beta secretion|negative regulation of interleukin-1 beta biosynthetic process http://purl.obolibrary.org/obo/GO_0032691 GO:0017054 biolink:CellularComponent negative cofactor 2 complex A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini. go-plus.json http://purl.obolibrary.org/obo/GO_0017054 GO:0017071 biolink:CellularComponent intracellular cyclic nucleotide activated cation channel complex A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0017071 GO:0017070 biolink:MolecularActivity U6 snRNA binding Binding to a U6 small nuclear RNA (U6 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0017070 GO:0017073 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017073 CHEBI:94442 biolink:ChemicalSubstance [3-carboxy-2-(1-oxohexadecoxy)propyl]-trimethylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_94442 GO:0017072 biolink:MolecularActivity obsolete tubulin-specific chaperone activity OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function. go-plus.json tubulin-specific chaperone activity http://purl.obolibrary.org/obo/GO_0017072 GO:0032689 biolink:BiologicalProcess negative regulation of interferon-gamma production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. go-plus.json inhibition of interferon-gamma production|negative regulation of interferon-gamma biosynthetic process|negative regulation of type II interferon production|down regulation of interferon-gamma production|downregulation of interferon-gamma production|negative regulation of interferon-gamma secretion|down-regulation of interferon-gamma production http://purl.obolibrary.org/obo/GO_0032689 GO:0032688 biolink:BiologicalProcess negative regulation of interferon-beta production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production. go-plus.json downregulation of interferon-beta production|negative regulation of interferon-beta secretion|down regulation of interferon-beta production|inhibition of interferon-beta production|down-regulation of interferon-beta production|negative regulation of IFN-beta production|negative regulation of interferon-beta biosynthetic process http://purl.obolibrary.org/obo/GO_0032688 GO:0032687 biolink:BiologicalProcess negative regulation of interferon-alpha production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production. go-plus.json negative regulation of interferon-alpha secretion|down regulation of interferon-alpha production|downregulation of interferon-alpha production|down-regulation of interferon-alpha production|inhibition of interferon-alpha production|negative regulation of interferon-alpha biosynthetic process http://purl.obolibrary.org/obo/GO_0032687 GO:0017068 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017068 GO:0017067 biolink:MolecularActivity tyrosine-ester sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+). RHEA:19977|MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN|EC:2.8.2.9|KEGG_REACTION:R04213 go-plus.json tyrosine-ester sulphotransferase activity|3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity|aryl sulfotransferase IV|L-tyrosine methyl ester sulfotransferase activity http://purl.obolibrary.org/obo/GO_0017067 GO:0032686 biolink:BiologicalProcess negative regulation of hepatocyte growth factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production. go-plus.json down-regulation of hepatocyte growth factor production|inhibition of hepatocyte growth factor production|negative regulation of hepatocyte growth factor biosynthetic process|down regulation of hepatocyte growth factor production|negative regulation of HGF production|downregulation of hepatocyte growth factor production|negative regulation of scatter factor production http://purl.obolibrary.org/obo/GO_0032686 GO:0032685 biolink:BiologicalProcess negative regulation of granulocyte macrophage colony-stimulating factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. go-plus.json down regulation of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony stimulating factor production|downregulation of granulocyte macrophage colony-stimulating factor production|down-regulation of granulocyte macrophage colony-stimulating factor production|inhibition of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|negative regulation of GM-CSF production http://purl.obolibrary.org/obo/GO_0032685 GO:0032684 biolink:BiologicalProcess negative regulation of fractalkine production Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production. go-plus.json down regulation of fractalkine production|inhibition of fractalkine production|negative regulation of CX3CL1 production|down-regulation of fractalkine production|negative regulation of fractalkine biosynthetic process|negative regulation of CX3CL1 biosynthesis|downregulation of fractalkine production http://purl.obolibrary.org/obo/GO_0032684 GO:0017069 biolink:MolecularActivity snRNA binding Binding to a small nuclear RNA (snRNA). go-plus.json base pairing with snRNA|small nuclear RNA binding http://purl.obolibrary.org/obo/GO_0017069 GO:0017064 biolink:MolecularActivity fatty acid amide hydrolase activity Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid. Reactome:R-HSA-5693751|Reactome:R-HSA-5693742 go-plus.json http://purl.obolibrary.org/obo/GO_0017064 GO:0032683 biolink:BiologicalProcess negative regulation of connective tissue growth factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production. go-plus.json negative regulation of Hcs24 production|negative regulation of Fisp12 production|negative regulation of IGFBP8 production|down-regulation of connective tissue growth factor production|negative regulation of CCN2 production|negative regulation of hypertrophic chondrocyte-specific gene product 24 production|negative regulation of connective tissue growth factor biosynthetic process|downregulation of connective tissue growth factor production|down regulation of connective tissue growth factor production|negative regulation of CTGF production|inhibition of connective tissue growth factor production http://purl.obolibrary.org/obo/GO_0032683 GO:0017063 biolink:MolecularActivity obsolete phosphatidylserine-specific phospholipase A1 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion. go-plus.json phosphatidylserine-specific phospholipase A1 activity http://purl.obolibrary.org/obo/GO_0017063 GO:0032682 biolink:BiologicalProcess negative regulation of chemokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production. go-plus.json down-regulation of chemokine production|negative regulation of chemokine biosynthetic process|downregulation of chemokine production|negative regulation of chemokine secretion|down regulation of chemokine production|inhibition of chemokine production http://purl.obolibrary.org/obo/GO_0032682 GO:0017066 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017066 GO:0032681 biolink:BiologicalProcess regulation of lymphotoxin A production Any process that modulates the frequency, rate, or extent of lymphotoxin A production. go-plus.json regulation of lymphotoxin A biosynthetic process|regulation of TNF-beta production|regulation of tumor necrosis factor-beta production|regulation of LTA production|regulation of lymphotoxin-alpha production http://purl.obolibrary.org/obo/GO_0032681 GO:0032680 biolink:BiologicalProcess regulation of tumor necrosis factor production Any process that modulates the frequency, rate or extent of tumor necrosis factor production. go-plus.json regulation of TNF production|regulation of tumor necrosis factor biosynthetic process|regulation of tumor necrosis factor secretion|regulation of tumor necrosis factor-alpha production|regulation of TNF-alpha production|regulation of cachectin production http://purl.obolibrary.org/obo/GO_0032680 GO:0017065 biolink:MolecularActivity single-strand selective uracil DNA N-glycosylase activity Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA. Reactome:R-HSA-110221 go-plus.json single-strand selective monofunctional uracil-DNA glycosylase activity http://purl.obolibrary.org/obo/GO_0017065 GO:0140588 biolink:BiologicalProcess chromatin looping A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome. go-plus.json chromatin loop assembly|chromatin folding http://purl.obolibrary.org/obo/GO_0140588 GO:0140587 biolink:MolecularActivity chromatin loop anchoring activity Bridging together two DNA loop anchors together, maintaining a chromatin loop. go-plus.json DNA loop binding|chromosomal loop binding http://purl.obolibrary.org/obo/GO_0140587 GO:0140580 biolink:MolecularActivity mitochondrion autophagosome adaptor activity The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome during mitophagy. go-plus.json mitophagy receptor http://purl.obolibrary.org/obo/GO_0140580 GO:0140582 biolink:BiologicalProcess adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway A series of molecular signals initiated by cAMP binding to its receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. go-plus.json extracellular cAMP signaling pathway http://purl.obolibrary.org/obo/GO_0140582 GO:0140581 biolink:MolecularActivity P-type monovalent copper transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out). RHEA:25792|EC:7.2.2.8 go-plus.json http://purl.obolibrary.org/obo/GO_0140581 GO:0140584 biolink:MolecularActivity chromatin extrusion motor activity A DNA translocase activity that folds chromosomal DNA and catalytically extends the newly formed loop, driven by ATP hydrolysis. go-plus.json chromatin extrusion activity http://purl.obolibrary.org/obo/GO_0140584 GO:0140586 biolink:MolecularActivity promoter-terminator loop anchoring activity Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop. go-plus.json terminator-promoter loop anchoring activity http://purl.obolibrary.org/obo/GO_0140586 GO:0140585 biolink:MolecularActivity promoter-enhancer loop anchoring activity Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop. go-plus.json enhancer-promoter loop anchoring activity http://purl.obolibrary.org/obo/GO_0140585 CHEBI:21415 biolink:ChemicalSubstance L-tyrosyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_21415 GO:0140576 biolink:BiologicalProcess ascorbate homeostasis Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell. go-plus.json cellular ascorbate homeostasis http://purl.obolibrary.org/obo/GO_0140576 GO:0140579 biolink:MolecularActivity obsolete oxidoreductase activity, reducing metal ions OBSOLETE. Catalysis of an oxidation-reduction in which the metal ion is reduced. go-plus.json http://purl.obolibrary.org/obo/GO_0140579 GO:0140571 biolink:MolecularActivity transmembrane ascorbate ferrireductase activity Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction. RHEA:30403|MetaCyc:1.10.2.1-RXN|EC:7.2.1.3 go-plus.json ascorbate-cytochrome b5 reductase activity|L-ascorbate-cytochrome-b5 reductase activity|L-ascorbate:ferricytochrome-b5 oxidoreductase activity http://purl.obolibrary.org/obo/GO_0140571 GO:0140570 biolink:BiologicalProcess extraction of mislocalized protein from mitochondrial outer membrane The removal of a mislocalized protein from the mitochondrial outer membrane. go-plus.json extraction of mislocalized protein from outer mitochondrion membrane http://purl.obolibrary.org/obo/GO_0140570 GO:0140573 biolink:CellularComponent histone H3-containing nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures. go-plus.json histone H3 containing nucleosome http://purl.obolibrary.org/obo/GO_0140573 GO:0140572 biolink:BiologicalProcess vacuole fission The division of a vacuole within a cell to form two or more separate vacuoles. go-plus.json http://purl.obolibrary.org/obo/GO_0140572 GO:0140575 biolink:MolecularActivity transmembrane monodehydroascorbate reductase activity Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction. RHEA:66524 go-plus.json http://purl.obolibrary.org/obo/GO_0140575 GO:0140599 biolink:CellularComponent mitotic nuclear bridge midzone membrane domain A nuclear membrane part at the midzone of the mitotic nuclear bridge. The midzone forms a bulge that is enriched in nuclear pores that lack baskets. go-plus.json http://purl.obolibrary.org/obo/GO_0140599 GO:0140598 biolink:MolecularActivity lipoprotein carrier activity Binding to and carrying a lipoprotein between two different cellular locations by moving along with the target lipoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0140598 GO:0140591 biolink:BiologicalProcess nuclear envelope budding The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. The enveloped particle fuses with the outer nuclear membrane and is released into the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0140591 GO:0140590 biolink:BiologicalProcess effector-mediated suppression of host defenses A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json effector-mediated suppression of host defenses by symbiont http://purl.obolibrary.org/obo/GO_0140590 GO:0140593 biolink:CellularComponent host apoplast The apoplast region surrounding a host plant cell. Plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json host cell apoplast http://purl.obolibrary.org/obo/GO_0140593 GO:0140592 biolink:MolecularActivity histone methyltransferase activity (H3-R8 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to arginine at position 8 of histone H3. go-plus.json http://purl.obolibrary.org/obo/GO_0140592 GO:0140595 biolink:CellularComponent MIM complex A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. MIM constitutes the major integration site for alpha-helical embedded proteins. In yeast, consists oof Mim1 and Mim2. go-plus.json mitochondrial outer import machinery http://purl.obolibrary.org/obo/GO_0140595 GO:0140594 biolink:MolecularActivity xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity Stops, prevents or reduces the activity of xyloglucan-specific endo-beta-1,4-glucanase. go-plus.json http://purl.obolibrary.org/obo/GO_0140594 GO:0140597 biolink:MolecularActivity protein carrier activity Binding to and carrying a protein between two different cellular locations by moving along with the target protein. go-plus.json protein carrier chaperone|protein chaperone http://purl.obolibrary.org/obo/GO_0140597 GO:0140596 biolink:CellularComponent TOM complex A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. TOM transports beta-barrel precursors across the outer membrane and the sorting and assembly machinery (SAM complex) inserts them into the target membrane. go-plus.json translocase of the outer mitochondrial membrane http://purl.obolibrary.org/obo/GO_0140596 CHEBI:7 biolink:ChemicalSubstance (+)-car-3-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_7 chebi_ph7_3 GO:0140544 biolink:BiologicalProcess septin collar organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar. go-plus.json cellular bud neck septin hourglass organization http://purl.obolibrary.org/obo/GO_0140544 GO:0140543 biolink:BiologicalProcess positive regulation of piRNA transcription Any process that increases the frequency, rate or extent of the synthesis of piRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140543 GO:0140546 biolink:BiologicalProcess defense response to symbiont Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont. go-plus.json http://purl.obolibrary.org/obo/GO_0140546 GO:0140545 biolink:MolecularActivity protein disaggregase activity An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates. go-plus.json http://purl.obolibrary.org/obo/GO_0140545 GO:0140548 biolink:BiologicalProcess envenomation resulting in blood agglutination in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism. go-plus.json envenomation resulting in erythrocytes agglutination in other organism|envenomation resulting in red blood cells agglutination in other organism http://purl.obolibrary.org/obo/GO_0140548 GO:0140547 biolink:BiologicalProcess acquisition of seed longevity The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes. go-plus.json http://purl.obolibrary.org/obo/GO_0140547 GO:0140549 biolink:CellularComponent spore inner membrane The membrane surrounding the spore core (endospore core) that separates it from its external environment. go-plus.json spore membrane http://purl.obolibrary.org/obo/GO_0140549 GO:0140540 biolink:BiologicalProcess negative regulation melanotic encapsulation of foreign target Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target. go-plus.json http://purl.obolibrary.org/obo/GO_0140540 GO:0140542 biolink:BiologicalProcess regulation of piRNA transcription Any process that modulates the frequency, rate or extent of the synthesis of a piRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140542 GO:0140541 biolink:BiologicalProcess piRNA transcription The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. go-plus.json PIWI-interacting RNA transcription|Piwi-associated RNA transcription http://purl.obolibrary.org/obo/GO_0140541 GO:0140533 biolink:BiologicalProcess suppression of host RNAi-mediated antiviral immune response Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json suppression of host RNAi-mediated gene silencing|suppression of host RNAi-mediated antiviral immunity http://purl.obolibrary.org/obo/GO_0140533 CHEBI:69404 biolink:ChemicalSubstance pestalamide A go-plus.json http://purl.obolibrary.org/obo/CHEBI_69404 GO:0140532 biolink:BiologicalProcess negative regulation of osmosensory signaling MAPK cascade Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0140532 CHEBI:69403 biolink:ChemicalSubstance carbonarone A go-plus.json http://purl.obolibrary.org/obo/CHEBI_69403 chebi_ph7_3 GO:0140535 biolink:CellularComponent intracellular protein-containing complex A protein-containing complex located intracellularly. go-plus.json http://purl.obolibrary.org/obo/GO_0140535 GO:0140534 biolink:CellularComponent endoplasmic reticulum protein-containing complex A protein complex that is part of an endoplasmic reticulum. go-plus.json http://purl.obolibrary.org/obo/GO_0140534 GO:0140537 biolink:MolecularActivity transcription regulator activator activity A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification. go-plus.json http://purl.obolibrary.org/obo/GO_0140537 GO:0140536 biolink:MolecularActivity nuclear receptor corepressor activity A transcription corepressor activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Nuclear receptor corepressors often act by altering chromatin structure and modifications. For example, one class of transcription nuclear receptor corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. go-plus.json nuclear corepressor activity http://purl.obolibrary.org/obo/GO_0140536 GO:0140539 biolink:BiologicalProcess regulation of melanotic encapsulation of foreign target Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target. go-plus.json http://purl.obolibrary.org/obo/GO_0140539 GO:0140538 biolink:BiologicalProcess negative regulation of conjugation with zygote A process that prevents a zygote from fusing an additional cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140538 GO:0140531 biolink:BiologicalProcess regulation of osmosensory signaling MAPK cascade Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0140531 GO:0140530 biolink:BiologicalProcess MCM complex loading The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly. go-plus.json MCM complex loading at replication origin|MCM double hexamer formation at replication origin http://purl.obolibrary.org/obo/GO_0140530 GO:0140566 biolink:MolecularActivity epigenetic reader A transcription regulator that recognizes epigenetic marks such as methylated cytosines in CpG islands and modified histones, and modulates the accessibility of cis-regulatory regions to the transcription machinery. go-plus.json http://purl.obolibrary.org/obo/GO_0140566 GO:0140568 biolink:BiologicalProcess extraction of mislocalized protein from membrane The removal of a mislocalized protein from a cellular membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140568 GO:0140567 biolink:MolecularActivity transmembrane protein dislocase activity The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. RHEA:66168 go-plus.json transmembrane helix dislocase http://purl.obolibrary.org/obo/GO_0140567 GO:0140569 biolink:BiologicalProcess extraction of mislocalized protein from ER membrane The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140569 GO:0140560 biolink:MolecularActivity xylosyl alpha-1,3-xylosyltransferase activity Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains. EC:2.4.2.62|RHEA:22820 go-plus.json http://purl.obolibrary.org/obo/GO_0140560 NCBITaxon:81824 biolink:OrganismalEntity Monosiga brevicollis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_81824 GO:0140562 biolink:MolecularActivity EGF-domain serine xylosyltransferase activity Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine. EC:2.4.2.63|RHEA:62016 go-plus.json http://purl.obolibrary.org/obo/GO_0140562 GO:0140561 biolink:MolecularActivity EGF-domain serine glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine. RHEA:58116|EC:2.4.1.376 go-plus.json http://purl.obolibrary.org/obo/GO_0140561 GO:0140564 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140564 GO:0140563 biolink:MolecularActivity UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. EC:2.4.2.42|RHEA:56064 go-plus.json http://purl.obolibrary.org/obo/GO_0140563 GO:0140554 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140554 NCBITaxon:1293361 biolink:OrganismalEntity Cenchrinae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1293361 GO:0140550 biolink:MolecularActivity phosphatidylinositol-4,5-bisphosphate sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0140550 GO:0140552 biolink:CellularComponent TEAD-YAP complex A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP. CORUM:2870 go-plus.json TEAD-4-YAP complex|TEAD-3-YAP complex|TEAD-2-YAP complex|TEAD-1-YAP complex|TEAD-2 multiprotein complex http://purl.obolibrary.org/obo/GO_0140552 CHEBI:21494 biolink:ChemicalSubstance N-acetoxyarylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21494 chebi_ph7_3 GO:0007639 biolink:BiologicalProcess homeostasis of number of meristem cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem. go-plus.json http://purl.obolibrary.org/obo/GO_0007639 GO:0007638 biolink:BiologicalProcess mechanosensory behavior Behavior that is dependent upon the sensation of a mechanical stimulus. go-plus.json mechanosensory behaviour|behavioural response to mechanical stimulus|behavioral response to mechanical stimulus http://purl.obolibrary.org/obo/GO_0007638 GO:0007637 biolink:BiologicalProcess proboscis extension reflex The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus. go-plus.json proboscis extension in response to nutritional stimulus|behavioral response to nutritional stimulus, proboscis extension http://purl.obolibrary.org/obo/GO_0007637 GO:0007636 biolink:BiologicalProcess chemosensory jump behavior The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance. go-plus.json jump response to chemical stimulus|chemosensory jump behaviour http://purl.obolibrary.org/obo/GO_0007636 GO:0007635 biolink:BiologicalProcess chemosensory behavior Behavior that is dependent upon the sensation of chemicals. go-plus.json chemosensory behaviour|behavioural response to chemical stimulus|behavioral response to chemical stimulus http://purl.obolibrary.org/obo/GO_0007635 CHEBI:21498 biolink:ChemicalSubstance N-acetyl-7-O-acetylneuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21498 GO:0007634 biolink:BiologicalProcess optokinetic behavior The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus. go-plus.json optokinetic behaviour http://purl.obolibrary.org/obo/GO_0007634 GO:0007633 biolink:BiologicalProcess pattern orientation The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes. go-plus.json behavioral response to pattern orientation|behavioural response to pattern orientation http://purl.obolibrary.org/obo/GO_0007633 GO:0007632 biolink:BiologicalProcess visual behavior The behavior of an organism in response to a visual stimulus. go-plus.json behavioral response to visual stimulus|visual behaviour|behavioural response to visual stimulus http://purl.obolibrary.org/obo/GO_0007632 GO:0007631 biolink:BiologicalProcess feeding behavior Behavior associated with the intake of food. Wikipedia:List_of_feeding_behaviours go-plus.json feeding from plant phloem|injection of substance into other organism during feeding on blood of other organism|hematophagy|feeding from tissue of other organism|eating|feeding from phloem of other organism|feeding on plant sap|feeding from xylem of other organism|behavioral response to food|feeding on blood of other organism|feeding on or from other organism|feeding from vascular tissue of another organism|feeding behaviour|behavioural response to food|taking of blood meal http://purl.obolibrary.org/obo/GO_0007631 GO:0007630 biolink:BiologicalProcess jump response The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0007630 CHEBI:3424 biolink:ChemicalSubstance carnitinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_3424 UBERON:0006846 biolink:AnatomicalEntity surface groove A furrow or an incomplete tube. go-plus.json groove http://purl.obolibrary.org/obo/UBERON_0006846 UBERON:0006843 biolink:AnatomicalEntity root of cranial nerve The initial segment of a cranial nerve, leaving the central nervous system. go-plus.json cranial nerve root|cranial neural root http://purl.obolibrary.org/obo/UBERON_0006843 CHEBI:176588 biolink:ChemicalSubstance oxidized icosatrienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176588 CHEBI:176587 biolink:ChemicalSubstance oxidized eicosatetraenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176587 UBERON:0006828 biolink:AnatomicalEntity trabecula carnea of atrium The supporting bundles of muscular fibers lining the walls of the atria[MP]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006828 UBERON:0006834 biolink:AnatomicalEntity uterus or analog A subdivision of a the reproductive tract in a female organism that is the site of embryo development. go-plus.json uterus http://purl.obolibrary.org/obo/UBERON_0006834 UBERON:0006833 biolink:AnatomicalEntity lumen of trachea An anatomical space that surrounded_by a trachea. go-plus.json lumen of cartilaginous trachea|tracheal lumen http://purl.obolibrary.org/obo/UBERON_0006833 GO:0007618 biolink:BiologicalProcess mating The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes. go-plus.json http://purl.obolibrary.org/obo/GO_0007618 GO:0007617 biolink:BiologicalProcess mating behavior The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. Wikipedia:Mating_behaviour go-plus.json mating behaviour http://purl.obolibrary.org/obo/GO_0007617 GO:0007616 biolink:BiologicalProcess long-term memory The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation. Wikipedia:Long-term_memory go-plus.json http://purl.obolibrary.org/obo/GO_0007616 GO:0007615 biolink:BiologicalProcess anesthesia-resistant memory The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0007615 GO:0007614 biolink:BiologicalProcess short-term memory The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation. Wikipedia:Short-term_memory go-plus.json http://purl.obolibrary.org/obo/GO_0007614 GO:0007613 biolink:BiologicalProcess memory The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). Wikipedia:Memory go-plus.json http://purl.obolibrary.org/obo/GO_0007613 GO:0007612 biolink:BiologicalProcess learning Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. Wikipedia:Learning go-plus.json http://purl.obolibrary.org/obo/GO_0007612 UBERON:0006815 biolink:AnatomicalEntity areolar connective tissue Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand. go-plus.json loose areolar connective tissue|loose connective tissue|areolar tissue http://purl.obolibrary.org/obo/UBERON_0006815 GO:0007611 biolink:BiologicalProcess learning or memory The acquisition and processing of information and/or the storage and retrieval of this information over time. go-plus.json http://purl.obolibrary.org/obo/GO_0007611 GO:0007610 biolink:BiologicalProcess behavior The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. Wikipedia:Behavior go-plus.json behaviour|behavioural response to stimulus|single-organism behavior|behavioral response to stimulus http://purl.obolibrary.org/obo/GO_0007610 goslim_flybase_ribbon|goslim_agr|gocheck_do_not_manually_annotate CHEBI:45441 biolink:ChemicalSubstance N-acetyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_45441 GO:0007619 biolink:BiologicalProcess courtship behavior The behavior of an organism for the purpose of attracting sexual partners. go-plus.json courtship behaviour http://purl.obolibrary.org/obo/GO_0007619 GO:0007629 biolink:BiologicalProcess flight behavior The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air. go-plus.json flight behaviour http://purl.obolibrary.org/obo/GO_0007629 GO:0007628 biolink:BiologicalProcess adult walking behavior The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg. go-plus.json adult walking behaviour http://purl.obolibrary.org/obo/GO_0007628 GO:0007627 biolink:BiologicalProcess obsolete larval behavior (sensu Insecta) OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects. go-plus.json larval behavior (sensu Insecta) http://purl.obolibrary.org/obo/GO_0007627 GO:0007626 biolink:BiologicalProcess locomotory behavior The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. go-plus.json locomotory behavioural response to stimulus|behavior via locomotion|locomotion in response to stimulus|locomotory behavioral response to stimulus|locomotory behaviour http://purl.obolibrary.org/obo/GO_0007626 goslim_drosophila GO:0007625 biolink:BiologicalProcess grooming behavior The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites. go-plus.json grooming behaviour http://purl.obolibrary.org/obo/GO_0007625 GO:0007624 biolink:BiologicalProcess ultradian rhythm The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours. go-plus.json http://purl.obolibrary.org/obo/GO_0007624 GO:0007623 biolink:BiologicalProcess circadian rhythm Any biological process in an organism that recurs with a regularity of approximately 24 hours. Wikipedia:Circadian_rhythm go-plus.json circadian process|circadian response|response to circadian rhythm http://purl.obolibrary.org/obo/GO_0007623 goslim_plant|goslim_drosophila GO:0007622 biolink:BiologicalProcess rhythmic behavior The specific behavior of an organism that recur with measured regularity. go-plus.json rhythmic behavioural response to stimulus|rhythmic behavioral response to stimulus|rhythmic behaviour http://purl.obolibrary.org/obo/GO_0007622 GO:0007621 biolink:BiologicalProcess negative regulation of female receptivity Any process that stops, prevents or reduces the receptiveness of a female to male advances. go-plus.json downregulation of female receptivity|down regulation of female receptivity|inhibition of female receptivity|down-regulation of female receptivity http://purl.obolibrary.org/obo/GO_0007621 GO:0007620 biolink:BiologicalProcess copulation The act of sexual union between male and female, involving the transfer of sperm. go-plus.json http://purl.obolibrary.org/obo/GO_0007620 UBERON:0006813 biolink:AnatomicalEntity nasal skeleton Structural framework that provides support to the nasal sacs and ducts. go-plus.json skeleton of nose http://purl.obolibrary.org/obo/UBERON_0006813 GO:0007607 biolink:BiologicalProcess obsolete taste perception OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal. go-plus.json taste perception http://purl.obolibrary.org/obo/GO_0007607 GO:0007606 biolink:BiologicalProcess sensory perception of chemical stimulus The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. go-plus.json chemosensory perception http://purl.obolibrary.org/obo/GO_0007606 GO:0007605 biolink:BiologicalProcess sensory perception of sound The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. Wikipedia:Hearing_(sense) go-plus.json perception of sound|hearing http://purl.obolibrary.org/obo/GO_0007605 GO:0007604 biolink:BiologicalProcess phototransduction, UV The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers. go-plus.json phototransduction, ultraviolet radiation|phototransduction, UV radiation|phototransduction, ultraviolet light|UV-sensitive opsin|phototransduction, UV light http://purl.obolibrary.org/obo/GO_0007604 GO:0007603 biolink:BiologicalProcess phototransduction, visible light The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. go-plus.json visual transduction|visual cascade http://purl.obolibrary.org/obo/GO_0007603 GO:0007602 biolink:BiologicalProcess phototransduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal. Wikipedia:Visual_phototransduction go-plus.json phototrophin mediated phototransduction|phototransduction, visible light, light adaptation|opsin http://purl.obolibrary.org/obo/GO_0007602 GO:0007601 biolink:BiologicalProcess visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. Wikipedia:Visual_perception go-plus.json vision|sense of sight|sensory visual perception http://purl.obolibrary.org/obo/GO_0007601 GO:0007600 biolink:BiologicalProcess sensory perception The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Wikipedia:Perception go-plus.json http://purl.obolibrary.org/obo/GO_0007600 goslim_drosophila CHEBI:45410 biolink:ChemicalSubstance (S)-2-hydroxypropylphosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45410 UBERON:0006872 biolink:AnatomicalEntity handplate apical ectodermal ridge An apical ectodermal ridge that is part of a handplate. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006872 UBERON:0006871 biolink:AnatomicalEntity embryonic footplate the distal elements of the developing limb of vertebrates that will give rise to the pes (foot) go-plus.json foot disk|footplate|foot plate|distal part of hindlimb bud http://purl.obolibrary.org/obo/UBERON_0006871 NCBITaxon:127906 biolink:OrganismalEntity Vibrio cholerae O1 go-plus.json Vibrio cholerae serogroup O1 http://purl.obolibrary.org/obo/NCBITaxon_127906 UBERON:0006877 biolink:AnatomicalEntity vasculature of liver A vasculature that is part of a liver. go-plus.json liver vascular system|hepatic vasculature|hepatic vascular element|liver vascular element http://purl.obolibrary.org/obo/UBERON_0006877 UBERON:0006876 biolink:AnatomicalEntity vasculature of organ A vasculature that is part of a organ. go-plus.json set of blood vessels of organ|organ vasculature http://purl.obolibrary.org/obo/UBERON_0006876 UBERON:0006875 biolink:AnatomicalEntity embryonic handplate the distal elements of the developing limb of vertebrates that will give rise to the manus (hand) go-plus.json handplate|hand plate|distal part of forelimb bud http://purl.obolibrary.org/obo/UBERON_0006875 GO:0007609 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007609 GO:0007608 biolink:BiologicalProcess sensory perception of smell The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. Wikipedia:Olfaction go-plus.json scent perception|olfaction|smell perception|sense of smell http://purl.obolibrary.org/obo/GO_0007608 UBERON:0006859 biolink:AnatomicalEntity swim bladder bud Embryonic structure that forms from the anterior gut epithelium at the level of the second somite that then matures to form the swim bladder. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006859 UBERON:0006861 biolink:AnatomicalEntity diaphysis proper Subdivision of long bone which forms the part of the bone between two metaphyses. Note that the diaphysis includes the metaphyses, but the diaphysis proper excludes these. go-plus.json long bone diaphysis|body proper of long bone|shaft proper of long bone http://purl.obolibrary.org/obo/UBERON_0006861 UBERON:0006860 biolink:AnatomicalEntity swim bladder A thin membranous, sometimes alveolated sac in the dorsal portion of the abdominal cavity. Contains a varying mixture of gases, not identical to the composition of air. May be one, two or three chambered. May be connected to the gut by a tube, the ductus pneumaticus (then called physostomous) or unconnected (then called physoclistous). go-plus.json gas bladder|swimbladder|fish maw|air bladder http://purl.obolibrary.org/obo/UBERON_0006860 CHEBI:21437 biolink:ChemicalSubstance Mo-molybdopterin cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_21437 UBERON:0006868 biolink:AnatomicalEntity seminal fluid secreting gland A gland that secretes a seminal fluid. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006868 UBERON:0006866 biolink:AnatomicalEntity terminal part of digestive tract The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. go-plus.json terminal section of digestive tract|rectal part of digestive tract|rectum http://purl.obolibrary.org/obo/UBERON_0006866 UBERON:0006865 biolink:AnatomicalEntity metaphysis of femur A metaphysis that is part of a femur. go-plus.json femoral metaphysis http://purl.obolibrary.org/obo/UBERON_0006865 UBERON:0006864 biolink:AnatomicalEntity distal metaphysis of femur A distal metaphysis that is part of a femur. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006864 UBERON:0006863 biolink:AnatomicalEntity proximal metaphysis of femur A proximal metaphysis that is part of a femur. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006863 UBERON:0006862 biolink:AnatomicalEntity diaphysis of femur A diaphysis that is part of a femur[Automatically generated definition]. go-plus.json femoral shaft|femoral diaphysis|shaft of femur|corpus femoris|body of femur http://purl.obolibrary.org/obo/UBERON_0006862 UBERON:0006849 biolink:AnatomicalEntity scapula Endochondral bone that is dorsoventrally compressed and provides attachment site for muscles of the pectoral appendage. go-plus.json scapulas|shoulder blade|scapulae|scapula bone http://purl.obolibrary.org/obo/UBERON_0006849 UBERON:0006858 biolink:AnatomicalEntity adrenal/interrenal gland This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells[GO] go-plus.json suprarenal gland - interrenal gland|adrenal - interrenal gland|adrenal gland/interrenal tissue|adrenal gland - interrenal gland http://purl.obolibrary.org/obo/UBERON_0006858 UBERON:0006855 biolink:AnatomicalEntity muscular coat of ureter A muscular coat that is part of a ureter. go-plus.json muscularis of ureter|muscular coat of ureter|tunica muscularis (ureter)|ureteral smooth muscle layer|tunica muscularis ureteris|muscular layer of ureter http://purl.obolibrary.org/obo/UBERON_0006855 UBERON:0006853 biolink:AnatomicalEntity renal cortex tubule A region of nephron tubule that is part of a cortex of kidney. go-plus.json kidney cortex tubule|cortical tubule http://purl.obolibrary.org/obo/UBERON_0006853 GO:0017161 biolink:MolecularActivity inositol-1,3,4-trisphosphate 4-phosphatase activity Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate. Reactome:R-HSA-1855180|RHEA:43392 go-plus.json http://purl.obolibrary.org/obo/GO_0017161 GO:0017160 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017160 GO:0032799 biolink:BiologicalProcess low-density lipoprotein receptor particle metabolic process The chemical reactions and pathways involving low-density lipoprotein receptors. go-plus.json low-density lipoprotein receptor metabolic process|LDL receptor metabolic process|low-density lipoprotein receptor metabolism http://purl.obolibrary.org/obo/GO_0032799 GO:0032798 biolink:CellularComponent Swi5-Sfr1 complex A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces). go-plus.json Sae3-Mei5 complex|Swi5 complex http://purl.obolibrary.org/obo/GO_0032798 GO:0042123 biolink:MolecularActivity glucanosyltransferase activity Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0042123 GO:0042122 biolink:BiologicalProcess alginic acid catabolic process The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds). go-plus.json alginic acid degradation|alginic acid breakdown|alginate catabolism|alginate catabolic process|alginic acid catabolism http://purl.obolibrary.org/obo/GO_0042122 GO:0042125 biolink:BiologicalProcess protein galactosylation The addition of a galactose molecule to a protein amino acid. go-plus.json protein amino acid galactosylation http://purl.obolibrary.org/obo/GO_0042125 GO:0042124 biolink:MolecularActivity 1,3-beta-glucanosyltransferase activity Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation. go-plus.json http://purl.obolibrary.org/obo/GO_0042124 GO:0042121 biolink:BiologicalProcess alginic acid biosynthetic process The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds). go-plus.json alginate biosynthetic process|alginate biosynthesis|alginic acid anabolism|alginic acid synthesis|alginic acid formation|alginic acid biosynthesis http://purl.obolibrary.org/obo/GO_0042121 GO:0042120 biolink:BiologicalProcess alginic acid metabolic process The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds). go-plus.json alginic acid metabolism|alginate metabolism|alginate metabolic process http://purl.obolibrary.org/obo/GO_0042120 CHEBI:137017 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137017 chebi_ph7_3 CHEBI:137016 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-arachidonoyl)ethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137016 chebi_ph7_3 GO:0042127 biolink:BiologicalProcess regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation. go-plus.json regulation of cell proliferation http://purl.obolibrary.org/obo/GO_0042127 GO:0017159 biolink:MolecularActivity pantetheine hydrolase activity Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine. KEGG_REACTION:R02973|RHEA:13445|EC:3.5.1.92|MetaCyc:3.5.1.92-RXN|Reactome:R-HSA-8938300 go-plus.json vanin|pantetheinase activity|(R)-pantetheine amidohydrolase activity|vanin-1 http://purl.obolibrary.org/obo/GO_0017159 GO:0042126 biolink:BiologicalProcess nitrate metabolic process The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid. go-plus.json nitrate metabolism http://purl.obolibrary.org/obo/GO_0042126 GO:0042129 biolink:BiologicalProcess regulation of T cell proliferation Any process that modulates the frequency, rate or extent of T cell proliferation. go-plus.json regulation of T lymphocyte proliferation|regulation of T-cell proliferation|regulation of T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0042129 GO:0042128 biolink:BiologicalProcess nitrate assimilation The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances. MetaCyc:PWY-381 go-plus.json assimilatory nitrate reduction http://purl.obolibrary.org/obo/GO_0042128 GO:0017156 biolink:BiologicalProcess calcium-ion regulated exocytosis The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. go-plus.json calcium ion-dependent exocytosis http://purl.obolibrary.org/obo/GO_0017156 GO:0032797 biolink:CellularComponent SMN complex A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus. go-plus.json SMN core complex|survival motor neuron complex http://purl.obolibrary.org/obo/GO_0032797 GO:0017155 biolink:MolecularActivity obsolete sodium:hydrogen antiporter regulator activity OBSOLETE. This term was not defined before being made obsolete. go-plus.json sodium:proton antiporter regulator|sodium:hydrogen antiporter regulator activity http://purl.obolibrary.org/obo/GO_0017155 GO:0032796 biolink:BiologicalProcess uropod organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated. go-plus.json uropod organisation|uropod organization and biogenesis http://purl.obolibrary.org/obo/GO_0032796 CHEBI:137010 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-oleoyl)ethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137010 chebi_ph7_3 GO:0017158 biolink:BiologicalProcess regulation of calcium ion-dependent exocytosis Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0017158 GO:0032795 biolink:MolecularActivity heterotrimeric G-protein binding Binding to a heterotrimeric G-protein. go-plus.json http://purl.obolibrary.org/obo/GO_0032795 GO:0017157 biolink:BiologicalProcess regulation of exocytosis Any process that modulates the frequency, rate or extent of exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0017157 GO:0032794 biolink:MolecularActivity GTPase activating protein binding Binding to a GTPase activating protein. go-plus.json GAP binding http://purl.obolibrary.org/obo/GO_0032794 CHEBI:137015 biolink:ChemicalSubstance 3-dehydro-scyllo-inosose go-plus.json http://purl.obolibrary.org/obo/CHEBI_137015 chebi_ph7_3 GO:0017152 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017152 GO:0032793 biolink:BiologicalProcess positive regulation of CREB transcription factor activity Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB. go-plus.json activation of CREB transcription factor|CREB activator|activation of CREB http://purl.obolibrary.org/obo/GO_0032793 GO:0017151 biolink:MolecularActivity DEAD/H-box RNA helicase binding Binding to a DEAD/H-box RNA helicase. go-plus.json http://purl.obolibrary.org/obo/GO_0017151 GO:0032792 biolink:BiologicalProcess negative regulation of CREB transcription factor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB. go-plus.json inhibition of CREB transcription factor|CREB inhibitor http://purl.obolibrary.org/obo/GO_0032792 GO:0032791 biolink:MolecularActivity lead ion binding Binding to lead (Pb) ions. go-plus.json http://purl.obolibrary.org/obo/GO_0032791 GO:0017154 biolink:MolecularActivity semaphorin receptor activity Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json http://purl.obolibrary.org/obo/GO_0017154 GO:0017153 biolink:MolecularActivity sodium:dicarboxylate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). go-plus.json sodium:dicarboxylate cotransporter activity http://purl.obolibrary.org/obo/GO_0017153 GO:0032790 biolink:BiologicalProcess ribosome disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. go-plus.json ribosome dissociation factor|ribosome recycling http://purl.obolibrary.org/obo/GO_0032790 GO:0017170 biolink:MolecularActivity obsolete KU70 binding OBSOLETE. Binding to Ku70, a protein involved in non-homologous DNA end joining. go-plus.json KU70 binding http://purl.obolibrary.org/obo/GO_0017170 GO:0017172 biolink:MolecularActivity cysteine dioxygenase activity Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+). MetaCyc:CYSTEINE-DIOXYGENASE-RXN|EC:1.13.11.20|Reactome:R-HSA-1614645|KEGG_REACTION:R00893|RHEA:20441 go-plus.json http://purl.obolibrary.org/obo/GO_0017172 GO:0017171 biolink:MolecularActivity serine hydrolase activity Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). go-plus.json http://purl.obolibrary.org/obo/GO_0017171 GO:0032789 biolink:BiologicalProcess unsaturated monocarboxylic acid metabolic process The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds. go-plus.json unsaturated monocarboxylic acid metabolism|unsaturated monocarboxylate metabolic process http://purl.obolibrary.org/obo/GO_0032789 GO:0032788 biolink:BiologicalProcess saturated monocarboxylic acid metabolic process The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds. go-plus.json saturated monocarboxylic acid metabolism|saturated monocarboxylate metabolic process http://purl.obolibrary.org/obo/GO_0032788 GO:0032787 biolink:BiologicalProcess monocarboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). go-plus.json monocarboxylic acid metabolism|monocarboxylate metabolic process http://purl.obolibrary.org/obo/GO_0032787 goslim_yeast GO:0042134 biolink:MolecularActivity rRNA primary transcript binding Binding to an unprocessed ribosomal RNA transcript. go-plus.json pre-rRNA binding http://purl.obolibrary.org/obo/GO_0042134 GO:0042133 biolink:BiologicalProcess neurotransmitter metabolic process The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. go-plus.json neurotransmitter metabolism http://purl.obolibrary.org/obo/GO_0042133 goslim_pir GO:0042136 biolink:BiologicalProcess neurotransmitter biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. go-plus.json neurotransmitter biosynthesis|neurotransmitter anabolism|neurotransmitter synthesis|neurotransmitter formation|neurotransmitter biosynthetic process and storage|neurotransmitter biosynthesis and storage http://purl.obolibrary.org/obo/GO_0042136 goslim_synapse GO:0042135 biolink:BiologicalProcess neurotransmitter catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. go-plus.json neurotransmitter breakdown|neurotransmitter degradation|neurotransmitter catabolism http://purl.obolibrary.org/obo/GO_0042135 goslim_synapse GO:0042130 biolink:BiologicalProcess negative regulation of T cell proliferation Any process that stops, prevents or reduces the rate or extent of T cell proliferation. go-plus.json negative regulation of T lymphocyte proliferation|downregulation of T cell proliferation|down regulation of T cell proliferation|inhibition of T cell proliferation|negative regulation of T-cell proliferation|negative regulation of T-lymphocyte proliferation|down-regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0042130 GO:0042132 biolink:MolecularActivity fructose 1,6-bisphosphate 1-phosphatase activity Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. EC:3.1.3.11|RHEA:11064|Reactome:R-HSA-70479|MetaCyc:F16BDEPHOS-RXN go-plus.json fructose bisphosphate phosphatase activity|D-fructose-1,6-bisphosphate 1-phosphohydrolase activity|fructose-1,6-bisphosphatase activity|hexose bisphosphatase activity|fructose 1,6-diphosphate phosphatase activity|fructose 1,6-diphosphatase activity|FBPase activity|D-fructose 1,6-diphosphatase activity|hexosediphosphatase activity|fructose 1,6-bisphosphate phosphatase activity|fructose 1,6-bisphosphatase activity|fructose-bisphosphatase activity|fructose diphosphate phosphatase activity|D-fructose-1,6-bisphosphate phosphatase activity|hexose diphosphatase activity|fructose diphosphatase activity http://purl.obolibrary.org/obo/GO_0042132 GO:0042131 biolink:MolecularActivity thiamine phosphate phosphatase activity Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate. go-plus.json thiamin monophosphate phosphatase|thiamin phosphate phosphatase activity|ThMPase http://purl.obolibrary.org/obo/GO_0042131 CHEBI:137029 biolink:ChemicalSubstance N,N-dihydroxy-L-tetrahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137029 CHEBI:137028 biolink:ChemicalSubstance N,N-dihydroxy-L-trihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137028 CHEBI:137027 biolink:ChemicalSubstance N,N-dihydroxy-L-dihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137027 GO:0042138 biolink:BiologicalProcess meiotic DNA double-strand break formation The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination. go-plus.json http://purl.obolibrary.org/obo/GO_0042138 GO:0042137 biolink:BiologicalProcess sequestering of neurotransmitter The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system. go-plus.json neurotransmitter retention|sequestration of neurotransmitter|neurotransmitter storage|neurotransmitter sequestration|neurotransmitter biosynthesis and storage|neurotransmitter biosynthetic process and storage|retention of neurotransmitter|storage of neurotransmitter http://purl.obolibrary.org/obo/GO_0042137 GO:0042139 biolink:BiologicalProcess early meiotic recombination nodule assembly During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene. go-plus.json http://purl.obolibrary.org/obo/GO_0042139 CHEBI:137022 biolink:ChemicalSubstance N-hydroxy-L-dihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137022 GO:0032786 biolink:BiologicalProcess positive regulation of DNA-templated transcription, elongation Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. go-plus.json positive regulation of DNA-dependent transcription, elongation|positive regulation of transcription elongation, DNA-dependent|upregulation of RNA elongation|positive regulation of transcription elongation|up-regulation of RNA elongation|positive regulation of transcriptional elongation|stimulation of RNA elongation|activation of RNA elongation|positive transcription elongation regulator activity|up regulation of RNA elongation http://purl.obolibrary.org/obo/GO_0032786 GO:0017167 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017167 CHEBI:137021 biolink:ChemicalSubstance 5(S),6(S)-epoxy-18(S)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137021 GO:0032785 biolink:BiologicalProcess negative regulation of DNA-templated transcription, elongation Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. go-plus.json downregulation of RNA elongation|down regulation of RNA elongation|negative regulation of transcription elongation|negative regulation of DNA-dependent transcription, elongation|negative regulation of transcription elongation, DNA-dependent|inhibition of RNA elongation|negative regulation of transcriptional elongation|down-regulation of RNA elongation|negative transcription elongation regulator activity http://purl.obolibrary.org/obo/GO_0032785 UBERON:5102389 biolink:AnatomicalEntity manual digit digitopodial skeleton A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit plus the associated metapodial element. go-plus.json manual digit|manual digit skeleton http://purl.obolibrary.org/obo/UBERON_5102389 GO:0017166 biolink:MolecularActivity vinculin binding Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0017166 GO:0032784 biolink:BiologicalProcess regulation of DNA-templated transcription, elongation Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. go-plus.json regulation of RNA elongation|transcription elongation regulator activity|regulation of transcriptional elongation|regulation of DNA-dependent transcription, elongation|regulation of transcription elongation, DNA-dependent http://purl.obolibrary.org/obo/GO_0032784 GO:0017169 biolink:MolecularActivity CDP-alcohol phosphatidyltransferase activity Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. go-plus.json http://purl.obolibrary.org/obo/GO_0017169 GO:0017168 biolink:MolecularActivity 5-oxoprolinase (ATP-hydrolyzing) activity Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate. MetaCyc:5-OXOPROLINASE-ATP-HYDROLYSING-RXN|Wikipedia:5-oxoprolinase_(ATP-hydrolysing)|RHEA:10348|EC:3.5.2.9|KEGG_REACTION:R00251|Reactome:R-HSA-5603208|Reactome:R-HSA-1247935 go-plus.json 5-oxo-L-prolinase activity|L-pyroglutamate hydrolase activity|pyroglutamate hydrolase activity|pyroglutamase (ATP-hydrolyzing) activity|5-oxoprolinase (ATP-hydrolysing)|5-OPase activity|pyroglutamase (ATP-hydrolysing)|pyroglutamase activity|5-oxoprolinase activity|pyroglutamic hydrolase activity|oxoprolinase activity|5-oxo-L-proline amidohydrolase (ATP-hydrolysing) http://purl.obolibrary.org/obo/GO_0017168 GO:0032783 biolink:CellularComponent super elongation complex A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae. go-plus.json ELL-EAF complex|ELL-EAF-EBP complex http://purl.obolibrary.org/obo/GO_0032783 CHEBI:137026 biolink:ChemicalSubstance N-hydroxy-L-hexahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137026 GO:0032782 biolink:BiologicalProcess bile acid secretion The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0032782 GO:0017163 biolink:MolecularActivity obsolete basal transcription repressor activity OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter. go-plus.json basal transcription repressor activity http://purl.obolibrary.org/obo/GO_0017163 GO:0032781 biolink:BiologicalProcess positive regulation of ATPase activity Any process that activates or increases the rate of ATP hydrolysis by an ATPase. go-plus.json positive regulation of adenosinetriphosphatase activity|up-regulation of ATPase activity|upregulation of ATPase activity|up regulation of ATPase activity|activation of ATPase activity|stimulation of ATPase activity http://purl.obolibrary.org/obo/GO_0032781 CHEBI:70399 biolink:ChemicalSubstance meleagrine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70399 chebi_ph7_3 GO:0017162 biolink:MolecularActivity aryl hydrocarbon receptor binding Binding to an aryl hydrocarbon receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0017162 CHEBI:137025 biolink:ChemicalSubstance N-hydroxy-L-pentahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137025 GO:0032780 biolink:BiologicalProcess negative regulation of ATPase activity Any process that stops or reduces the rate of ATP hydrolysis by an ATPase. go-plus.json inhibition of ATPase activity|down regulation of ATPase activity|downregulation of ATPase activity|negative regulation of adenosinetriphosphatase activity|down-regulation of ATPase activity http://purl.obolibrary.org/obo/GO_0032780 GO:0017165 biolink:MolecularActivity obsolete dipeptidase E activity OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides. go-plus.json peptidase E activity|PepE gene product (Salmonella typhimurium) activity|aspartyl dipeptidase activity|dipeptidase E activity|alpha-aspartyl dipeptidase activity http://purl.obolibrary.org/obo/GO_0017165 CHEBI:137024 biolink:ChemicalSubstance N-hydroxy-L-tetrahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137024 GO:0017164 biolink:MolecularActivity obsolete nicotinic acetylcholine receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json nicotinic acetylcholine receptor-associated protein activity http://purl.obolibrary.org/obo/GO_0017164 CHEBI:137023 biolink:ChemicalSubstance N-hydroxy-L-trihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137023 GO:0032779 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032779 GO:0032778 biolink:MolecularActivity P-type cobalt transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in). RHEA:32779 go-plus.json cobalt-transporting ATPase activity|cobalt transporting ATPase activity|ATP-dependent cobalt transmembrane transporter activity|ATPase-coupled cobalt transmembrane transporter activity|cobalt porter activity http://purl.obolibrary.org/obo/GO_0032778 GO:0032777 biolink:CellularComponent Piccolo NuA4 histone acetyltransferase complex A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p. go-plus.json http://purl.obolibrary.org/obo/GO_0032777 GO:0032776 biolink:BiologicalProcess DNA methylation on cytosine The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule. go-plus.json cytosine methylation http://purl.obolibrary.org/obo/GO_0032776 GO:0042145 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042145 GO:0042144 biolink:BiologicalProcess vacuole fusion, non-autophagic The fusion of two vacuole membranes to form a single vacuole. go-plus.json vacuole fusion (non-autophagic)|homotypic vacuole fusion (non-autophagic)|homotypic vacuole fusion|homotypic vacuole fusion, non-autophagic http://purl.obolibrary.org/obo/GO_0042144 GO:0042147 biolink:BiologicalProcess retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport. go-plus.json retrograde (endosome to Golgi) transport http://purl.obolibrary.org/obo/GO_0042147 GO:0042146 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042146 GO:0042141 biolink:MolecularActivity obsolete mating pheromone exporter OBSOLETE. Exports diffusible peptide signals that are responsible for binding to other cells and triggering a series of responses to facilitate mating. go-plus.json mating pheromone exporter http://purl.obolibrary.org/obo/GO_0042141 GO:0042140 biolink:BiologicalProcess late meiotic recombination nodule assembly During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over. go-plus.json http://purl.obolibrary.org/obo/GO_0042140 GO:0042143 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042143 GO:0042142 biolink:BiologicalProcess obsolete heavy metal chelation OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein. go-plus.json heavy metal chelation http://purl.obolibrary.org/obo/GO_0042142 GO:0042149 biolink:BiologicalProcess cellular response to glucose starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose. go-plus.json http://purl.obolibrary.org/obo/GO_0042149 GO:0017138 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017138 GO:0042148 biolink:BiologicalProcess strand invasion The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. go-plus.json Rad51-mediated strand invasion|D-loop biosynthesis|D-loop formation|displacement loop biosynthesis|displacement loop formation http://purl.obolibrary.org/obo/GO_0042148 GO:0017137 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017137 GO:0017139 biolink:BiologicalProcess obsolete arsenate sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json arsenate sensitivity/resistance http://purl.obolibrary.org/obo/GO_0017139 GO:0032775 biolink:BiologicalProcess DNA methylation on adenine The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule. go-plus.json adenine methylation http://purl.obolibrary.org/obo/GO_0032775 GO:0017134 biolink:MolecularActivity fibroblast growth factor binding Binding to a fibroblast growth factor. go-plus.json FGF binding|FGF 6 binding|FGF 5 binding|fibroblast growth factor 6 binding|fibroblast growth factor 5 binding|FGF 4 binding|FGF 3 binding|fibroblast growth factor 4 binding|fibroblast growth factor 3 binding|FGF 2 binding|FGF 1 binding|fibroblast growth factor 2 binding|fibroblast growth factor 1 binding http://purl.obolibrary.org/obo/GO_0017134 GO:0032774 biolink:BiologicalProcess RNA biosynthetic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. go-plus.json RNA biosynthesis|RNA anabolism|RNA synthesis|RNA formation http://purl.obolibrary.org/obo/GO_0032774 GO:0017133 biolink:CellularComponent mitochondrial electron transfer flavoprotein complex A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system. go-plus.json http://purl.obolibrary.org/obo/GO_0017133 GO:0017136 biolink:MolecularActivity NAD-dependent histone deacetylase activity Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone. go-plus.json SIR2 http://purl.obolibrary.org/obo/GO_0017136 GO:0032773 biolink:BiologicalProcess positive regulation of tyrosinase activity Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase. go-plus.json up regulation of monophenol oxygenase activity|activation of monophenol oxygenase activity|positive regulation of monophenol monooxygenase activity|stimulation of monophenol oxygenase activity|up-regulation of monophenol oxygenase activity|positive regulation of monophenol oxygenase activity|upregulation of monophenol oxygenase activity http://purl.obolibrary.org/obo/GO_0032773 GO:0017135 biolink:MolecularActivity obsolete membrane-associated protein with guanylate kinase activity interacting OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity. go-plus.json membrane-associated protein with guanylate kinase activity interacting http://purl.obolibrary.org/obo/GO_0017135 GO:0032772 biolink:BiologicalProcess negative regulation of tyrosinase activity Any process that stops or reduces the activity of a tyrosinase enzyme. go-plus.json down regulation of monophenol oxygenase activity|downregulation of monophenol oxygenase activity|down-regulation of monophenol oxygenase activity|negative regulation of monophenol monooxygenase activity|inhibition of monophenol oxygenase activity|negative regulation of monophenol oxygenase activity http://purl.obolibrary.org/obo/GO_0032772 GO:0017130 biolink:MolecularActivity poly(C) RNA binding Binding to a sequence of cytosine residues in an RNA molecule. go-plus.json poly(rC) binding|poly(C) binding http://purl.obolibrary.org/obo/GO_0017130 GO:0032771 biolink:BiologicalProcess regulation of tyrosinase activity Any process that modulates the activity of a tyrosinase enzyme. go-plus.json regulation of monophenol monooxygenase activity|regulation of monophenol oxygenase activity http://purl.obolibrary.org/obo/GO_0032771 GO:0032770 biolink:BiologicalProcess positive regulation of monooxygenase activity Any process that activates or increases the activity of a monooxygenase. go-plus.json stimulation of monooxygenase activity|up-regulation of monooxygenase activity|activation of monooxygenase activity|up regulation of monooxygenase activity|upregulation of monooxygenase activity http://purl.obolibrary.org/obo/GO_0032770 GO:0017132 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017132 GO:0017131 biolink:MolecularActivity uridine-rich cytoplasmic polyadenylylation element binding Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation. go-plus.json U-rich CPE binding|uridine-rich cytoplasmic polyadenylation element binding http://purl.obolibrary.org/obo/GO_0017131 CHEBI:176642 biolink:ChemicalSubstance oxidized ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_176642 GO:0042150 biolink:BiologicalProcess plasmid recombination A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0042150 CHEBI:45394 biolink:ChemicalSubstance TMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_45394 GO:0017150 biolink:MolecularActivity tRNA dihydrouridine synthase activity Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor. Reactome:R-HSA-6782296|RHEA:23624|MetaCyc:RXN0-1281 go-plus.json http://purl.obolibrary.org/obo/GO_0017150 GO:0032769 biolink:BiologicalProcess negative regulation of monooxygenase activity Any process that stops or reduces the activity of a monooxygenase. go-plus.json down-regulation of monooxygenase activity|downregulation of monooxygenase activity|down regulation of monooxygenase activity|inhibition of monooxygenase activity http://purl.obolibrary.org/obo/GO_0032769 GO:0032768 biolink:BiologicalProcess regulation of monooxygenase activity Any process that modulates the activity of a monooxygenase. go-plus.json http://purl.obolibrary.org/obo/GO_0032768 GO:0032767 biolink:MolecularActivity copper-dependent protein binding Binding to a protein or protein complex, in the presence of copper. go-plus.json http://purl.obolibrary.org/obo/GO_0032767 GO:0032766 biolink:CellularComponent NHE3/E3KARP/ACTN4 complex A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments. go-plus.json NHE3/E3KARP/alpha-actinin complex http://purl.obolibrary.org/obo/GO_0032766 GO:0032765 biolink:BiologicalProcess positive regulation of mast cell cytokine production Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production. go-plus.json up-regulation of mast cell cytokine production|upregulation of mast cell cytokine production|up regulation of mast cell cytokine production|activation of mast cell cytokine production|stimulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0032765 GO:0042156 biolink:MolecularActivity obsolete zinc-mediated transcriptional activator activity OBSOLETE. Initiates or upregulates transcription in the presence of zinc. go-plus.json zinc-mediated transcriptional activator activity http://purl.obolibrary.org/obo/GO_0042156 GO:0042155 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042155 GO:0042158 biolink:BiologicalProcess lipoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. go-plus.json lipoprotein biosynthesis|lipoprotein anabolism|lipoprotein synthesis|lipoprotein formation http://purl.obolibrary.org/obo/GO_0042158 goslim_pombe GO:0042157 biolink:BiologicalProcess lipoprotein metabolic process The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. go-plus.json lipoprotein metabolism http://purl.obolibrary.org/obo/GO_0042157 GO:0042152 biolink:BiologicalProcess RNA-mediated DNA recombination The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele. go-plus.json http://purl.obolibrary.org/obo/GO_0042152 OBO:chebi#is_conjugate_acid_of biolink:OntologyClass is conjugate acid of go-plus.json http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of GO:0042151 biolink:CellularComponent nematocyst An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus. Wikipedia:Cnidocyte go-plus.json cnidocyst http://purl.obolibrary.org/obo/GO_0042151 GO:0042154 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042154 GO:0042153 biolink:MolecularActivity obsolete RPTP-like protein binding OBSOLETE. Binding to proteins with similar structure/function to receptor protein tyrosine phosphatases. go-plus.json RPTP-like protein binding|receptor protein tyrosine phosphatase-like protein binding http://purl.obolibrary.org/obo/GO_0042153 CHEBI:137007 biolink:ChemicalSubstance N,N-dihydroxy-L-polyhomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137007 CHEBI:137006 biolink:ChemicalSubstance N-hydroxy-L-polyhomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137006 CHEBI:3259 biolink:ChemicalSubstance CCCP go-plus.json http://purl.obolibrary.org/obo/CHEBI_3259 chebi_ph7_3 CHEBI:137005 biolink:ChemicalSubstance L-hexahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137005 GO:0017149 biolink:MolecularActivity obsolete protein biosynthetic process inhibitor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json protein biosynthetic process inhibitor activity|protein formation inhibitor activity|protein synthesis inhibitor activity|protein anabolism inhibitor activity http://purl.obolibrary.org/obo/GO_0017149 GO:0017148 biolink:BiologicalProcess negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. go-plus.json downregulation of protein biosynthetic process|negative regulation of protein anabolism|down regulation of protein biosynthetic process|negative regulation of protein synthesis|inhibition of protein biosynthetic process|protein biosynthetic process inhibitor activity|protein biosynthesis inhibitor activity|negative regulation of protein formation|negative regulation of protein biosynthesis|down-regulation of protein biosynthetic process|negative regulation of protein biosynthetic process http://purl.obolibrary.org/obo/GO_0017148 GO:0042159 biolink:BiologicalProcess lipoprotein catabolic process The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. go-plus.json lipoprotein degradation|lipoprotein breakdown|lipoprotein catabolism http://purl.obolibrary.org/obo/GO_0042159 CHEBI:137009 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-hexadecanoyl)ethanolamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137009 chebi_ph7_3 GO:0032764 biolink:BiologicalProcess negative regulation of mast cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production. go-plus.json inhibition of mast cell cytokine production|down regulation of mast cell cytokine production|downregulation of mast cell cytokine production|down-regulation of mast cell cytokine production http://purl.obolibrary.org/obo/GO_0032764 GO:0017145 biolink:BiologicalProcess stem cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. go-plus.json stem cell renewal http://purl.obolibrary.org/obo/GO_0017145 CHEBI:137000 biolink:ChemicalSubstance C-terminal Xaa-Gly(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137000 chebi_ph7_3 GO:0017144 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017144 GO:0032763 biolink:BiologicalProcess regulation of mast cell cytokine production Any process that modulates the frequency, rate, or extent of mast cell cytokine production. go-plus.json http://purl.obolibrary.org/obo/GO_0032763 GO:0017147 biolink:MolecularActivity Wnt-protein binding Binding to a Wnt-protein, a secreted growth factor involved in signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0017147 goslim_chembl GO:0032762 biolink:BiologicalProcess mast cell cytokine production Any process that contributes to cytokine production by a mast cell. go-plus.json http://purl.obolibrary.org/obo/GO_0032762 gocheck_do_not_annotate GO:0017146 biolink:CellularComponent NMDA selective glutamate receptor complex An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD. go-plus.json N-methyl-D-aspartate selective glutamate receptor complex|NMDA-selective glutamate receptor http://purl.obolibrary.org/obo/GO_0017146 GO:0032761 biolink:BiologicalProcess positive regulation of lymphotoxin A production Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production. go-plus.json upregulation of lymphotoxin A production|positive regulation of LTA production|positive regulation of lymphotoxin-alpha production|stimulation of lymphotoxin A production|up-regulation of lymphotoxin A production|activation of lymphotoxin A production|positive regulation of TNF-beta production|positive regulation of tumor necrosis factor-beta production|up regulation of lymphotoxin A production|positive regulation of lymphotoxin A biosynthetic process http://purl.obolibrary.org/obo/GO_0032761 GO:0032760 biolink:BiologicalProcess positive regulation of tumor necrosis factor production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production. go-plus.json positive regulation of tumor necrosis factor-alpha production|positive regulation of TNF-alpha production|stimulation of tumor necrosis factor production|up-regulation of tumor necrosis factor production|activation of tumor necrosis factor production|positive regulation of tumor necrosis factor secretion|positive regulation of cachectin secretion|positive regulation of TNF production|up regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor formation|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of tumor necrosis factor biosynthesis|positive regulation of TNF secretion|upregulation of tumor necrosis factor production http://purl.obolibrary.org/obo/GO_0032760 CHEBI:137004 biolink:ChemicalSubstance L-pentahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137004 GO:0017141 biolink:BiologicalProcess obsolete antibiotic susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json antibiotic susceptibility/resistance http://purl.obolibrary.org/obo/GO_0017141 CHEBI:137003 biolink:ChemicalSubstance C-terminal Xaa-hydroxyglycino(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137003 chebi_ph7_3 GO:0017140 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017140 GO:0017143 biolink:BiologicalProcess insecticide metabolic process The chemical reactions and pathways involving insecticides, chemicals used to kill insects. go-plus.json insecticide metabolism http://purl.obolibrary.org/obo/GO_0017143 CHEBI:137002 biolink:ChemicalSubstance L-tetrahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137002 GO:0017142 biolink:BiologicalProcess obsolete toxin susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). go-plus.json toxin susceptibility/resistance http://purl.obolibrary.org/obo/GO_0017142 CHEBI:137001 biolink:ChemicalSubstance C-terminal alpha-amino-acid amide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137001 chebi_ph7_3 GO:0042161 biolink:BiologicalProcess lipoprotein oxidation The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group. go-plus.json http://purl.obolibrary.org/obo/GO_0042161 GO:0032759 biolink:BiologicalProcess positive regulation of TRAIL production Any process that activates or increases the frequency, rate, or extent of TRAIL production. go-plus.json up regulation of TRAIL production|positive regulation of TRAIL biosynthetic process|upregulation of TRAIL production|stimulation of TRAIL production|up-regulation of TRAIL production|activation of TRAIL production http://purl.obolibrary.org/obo/GO_0032759 UBERON:0006919 biolink:AnatomicalEntity tongue squamous epithelium A squamous epithelium that is part of a tongue. go-plus.json squamous epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0006919 GO:0042160 biolink:BiologicalProcess lipoprotein modification The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. go-plus.json http://purl.obolibrary.org/obo/GO_0042160 GO:0032758 biolink:BiologicalProcess positive regulation of interleukin-9 production Any process that activates or increases the frequency, rate, or extent of interleukin-9 production. go-plus.json positive regulation of IL-9 production|positive regulation of interleukin-9 biosynthetic process|upregulation of interleukin-9 production|stimulation of interleukin-9 production|activation of interleukin-9 production|up-regulation of interleukin-9 production|up regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0032758 GO:0032757 biolink:BiologicalProcess positive regulation of interleukin-8 production Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. go-plus.json positive regulation of IL-8 production|positive regulation of interleukin-8 biosynthetic process|upregulation of interleukin-8 production|stimulation of interleukin-8 production|up-regulation of interleukin-8 production|activation of interleukin-8 production|positive regulation of interleukin-8 secretion|up regulation of interleukin-8 production http://purl.obolibrary.org/obo/GO_0032757 GO:0032756 biolink:BiologicalProcess positive regulation of interleukin-7 production Any process that activates or increases the frequency, rate, or extent of interleukin-7 production. go-plus.json upregulation of interleukin-7 production|stimulation of interleukin-7 production|activation of interleukin-7 production|up-regulation of interleukin-7 production|positive regulation of interleukin-7 secretion|up regulation of interleukin-7 production|positive regulation of interleukin-7 biosynthetic process|positive regulation of IL-7 production http://purl.obolibrary.org/obo/GO_0032756 UBERON:0006916 biolink:AnatomicalEntity non-keratinized epithelium of tongue A non-keratinized stratified squamous epithelium that is part of a tongue. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006916 UBERON:0006915 biolink:AnatomicalEntity stratified squamous epithelium Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA] go-plus.json epithelium stratificatum squamosum http://purl.obolibrary.org/obo/UBERON_0006915 GO:0032755 biolink:BiologicalProcess positive regulation of interleukin-6 production Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. go-plus.json upregulation of interleukin-6 production|stimulation of interleukin-6 production|up-regulation of interleukin-6 production|activation of interleukin-6 production|positive regulation of interleukin-6 secretion|up regulation of interleukin-6 production|positive regulation of IL-6 production|positive regulation of interleukin-6 biosynthetic process http://purl.obolibrary.org/obo/GO_0032755 GO:0032754 biolink:BiologicalProcess positive regulation of interleukin-5 production Any process that activates or increases the frequency, rate, or extent of interleukin-5 production. go-plus.json upregulation of interleukin-5 production|stimulation of interleukin-5 production|up-regulation of interleukin-5 production|activation of interleukin-5 production|positive regulation of interleukin-5 secretion|up regulation of interleukin-5 production|positive regulation of IL-5 production|positive regulation of interleukin-5 biosynthetic process http://purl.obolibrary.org/obo/GO_0032754 UBERON:0006914 biolink:AnatomicalEntity squamous epithelium An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006914 GO:0042167 biolink:BiologicalProcess heme catabolic process The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. go-plus.json haem catabolic process|heme degradation|heme catabolism|heme breakdown|haem catabolism http://purl.obolibrary.org/obo/GO_0042167 GO:0042166 biolink:MolecularActivity acetylcholine binding Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0042166 GO:0042169 biolink:MolecularActivity SH2 domain binding Binding to a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class. go-plus.json http://purl.obolibrary.org/obo/GO_0042169 GO:0042168 biolink:BiologicalProcess heme metabolic process The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. go-plus.json haem metabolic process|heme metabolism|haem metabolism http://purl.obolibrary.org/obo/GO_0042168 GO:0042163 biolink:MolecularActivity interleukin-12 beta subunit binding Binding to the beta subunit of interleukin-12. go-plus.json NKSFp40 binding|IL-12B binding|CLMFp40 binding|IL-12p40 binding http://purl.obolibrary.org/obo/GO_0042163 CHEBI:45389 biolink:ChemicalSubstance (R)-styrene oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_45389 chebi_ph7_3 GO:0042162 biolink:MolecularActivity telomeric DNA binding Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. go-plus.json telomeric repeat binding|telomere binding http://purl.obolibrary.org/obo/GO_0042162 GO:0042165 biolink:MolecularActivity neurotransmitter binding Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. go-plus.json http://purl.obolibrary.org/obo/GO_0042165 goslim_pir GO:0042164 biolink:MolecularActivity interleukin-12 alpha subunit binding Binding to the alpha subunit of interleukin-12. go-plus.json IL-12A binding|CLMFp35 binding|IL-12p35 binding|NKSFp35 binding http://purl.obolibrary.org/obo/GO_0042164 GO:0017119 biolink:CellularComponent Golgi transport complex A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. Composed of 8 subunits COG1-8. go-plus.json Sec34/35 complex|COG complex|conserved oligomeric Golgi complex http://purl.obolibrary.org/obo/GO_0017119 NCBITaxon:91061 biolink:OrganismalEntity Bacilli go-plus.json Bacillus/Lactobacillus/Streptococcus group|Firmibacteria http://purl.obolibrary.org/obo/NCBITaxon_91061 GO:0017116 biolink:MolecularActivity single-stranded DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix. go-plus.json ssDNA-dependent ATP-dependent DNA helicase activity|single-stranded DNA-dependent ATPase activity|ssDNA-dependent ATPase activity|single-stranded DNA-dependent ATP-dependent DNA helicase activity http://purl.obolibrary.org/obo/GO_0017116 GO:0017115 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017115 GO:0017118 biolink:MolecularActivity lipoyltransferase activity Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme. RHEA:20473 go-plus.json http://purl.obolibrary.org/obo/GO_0017118 GO:0017117 biolink:CellularComponent single-stranded DNA-dependent ATP-dependent DNA helicase complex A protein complex that possesses single-stranded DNA-dependent DNA helicase activity. go-plus.json ssDNA-dependent ATP-dependent DNA helicase complex http://purl.obolibrary.org/obo/GO_0017117 GO:0032753 biolink:BiologicalProcess positive regulation of interleukin-4 production Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. go-plus.json stimulation of interleukin-4 production|up-regulation of interleukin-4 production|activation of interleukin-4 production|up regulation of interleukin-4 production|positive regulation of interleukin-4 secretion|positive regulation of IL-4 production|positive regulation of interleukin-4 biosynthetic process|upregulation of interleukin-4 production http://purl.obolibrary.org/obo/GO_0032753 UBERON:0006924 biolink:AnatomicalEntity stomach glandular epithelium A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands. go-plus.json epithelium of gastric gland|gastric gland epithelium http://purl.obolibrary.org/obo/UBERON_0006924 GO:0017112 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017112 GO:0017111 biolink:MolecularActivity nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. Reactome:R-HSA-8850846|MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN|RHEA:23680|Reactome:R-HSA-8851538|Reactome:R-HSA-8851234|Reactome:R-HSA-8851089|Reactome:R-HSA-8851110|Reactome:R-HSA-8851494 go-plus.json nucleoside-5-triphosphate phosphohydrolase activity|unspecific diphosphate phosphohydrolase activity|nucleoside triphosphate hydrolase activity|nucleoside triphosphate phosphohydrolase activity|nucleoside 5-triphosphatase activity|NTPase activity|nucleoside triphosphatase activity|apyrase activity http://purl.obolibrary.org/obo/GO_0017111 goslim_chembl|goslim_metagenomics GO:0032752 biolink:BiologicalProcess positive regulation of interleukin-3 production Any process that activates or increases the frequency, rate, or extent of interleukin-3 production. go-plus.json stimulation of interleukin-3 production|up-regulation of interleukin-3 production|activation of interleukin-3 production|up regulation of interleukin-3 production|positive regulation of IL-3 production|positive regulation of interleukin-3 biosynthetic process|upregulation of interleukin-3 production http://purl.obolibrary.org/obo/GO_0032752 UBERON:0006923 biolink:AnatomicalEntity vagina squamous epithelium A squamous epithelium that is part of a vagina. go-plus.json vaginal squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006923 GO:0032751 biolink:BiologicalProcess positive regulation of interleukin-27 production Any process that activates or increases the frequency, rate, or extent of interleukin-27 production. go-plus.json upregulation of interleukin-27 production|positive regulation of IL-27 production|up regulation of interleukin-27 production|activation of interleukin-27 production|stimulation of interleukin-27 production|positive regulation of interleukin-27 anabolism|positive regulation of interleukin-27 biosynthetic process|up-regulation of interleukin-27 production http://purl.obolibrary.org/obo/GO_0032751 UBERON:0006922 biolink:AnatomicalEntity cervix squamous epithelium The squamous epithelium of the cervical portio is similar to that of the vagina, except that it is generally smooth and lacks rete pegs. Colposcopically, it appears featureless except for a fine network of vessels which is sometimes visible. The relative opacity and pale pink coloration of the squamous epithelium derives from its multi-layered histology and the location of its supporting vessels below the basement membrane. go-plus.json cervical squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006922 GO:0017114 biolink:MolecularActivity obsolete wide-spectrum protease inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease. go-plus.json wide-spectrum proteinase inhibitor|wide-spectrum protease inhibitor activity http://purl.obolibrary.org/obo/GO_0017114 GO:0017113 biolink:MolecularActivity dihydropyrimidine dehydrogenase (NADP+) activity Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+. Reactome:R-HSA-73616|Reactome:R-HSA-73585|MetaCyc:1.3.1.2-RXN|EC:1.3.1.2|RHEA:18093 go-plus.json dihydrouracil dehydrogenase (NADP+) activity|dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)|dihydrouracil dehydrogenase (NADP)|4,5-dihydrothymine: oxidoreductase activity|DPD|5,6-dihydrouracil:NADP+ 5-oxidoreductase activity|hydropyrimidine dehydrogenase activity|dihydrothymine dehydrogenase activity|DHPDH|dihydropyrimidine dehydrogenase activity|DHU dehydrogenase activity http://purl.obolibrary.org/obo/GO_0017113 GO:0032750 biolink:BiologicalProcess positive regulation of interleukin-26 production Any process that activates or increases the frequency, rate, or extent of interleukin-26 production. go-plus.json upregulation of interleukin-26 production|positive regulation of IL-26 production|up regulation of interleukin-26 production|activation of interleukin-26 production|stimulation of interleukin-26 production|positive regulation of interleukin-26 biosynthetic process|up-regulation of interleukin-26 production http://purl.obolibrary.org/obo/GO_0032750 UBERON:0006921 biolink:AnatomicalEntity stomach squamous epithelium A squamous epithelium that is part of a stomach. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006921 UBERON:0006920 biolink:AnatomicalEntity esophagus squamous epithelium A squamous epithelium that is part of a esophagus. go-plus.json squamous oesophageal epithelium|squamous epithelium of esophagus|esophageal squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006920 GO:0017110 biolink:MolecularActivity nucleoside-diphosphatase activity Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate. RHEA:36799|Reactome:R-HSA-8851129|EC:3.6.1.6|Reactome:R-HSA-8851225|Reactome:R-HSA-8850854|Reactome:R-HSA-8851356|Reactome:R-HSA-8851550|Reactome:R-HSA-8851396|Reactome:R-HSA-2395876|MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN go-plus.json nucleoside-diphosphate phosphohydrolase activity|inosine diphosphatase|type B nucleoside diphosphatase|inosine 5'-diphosphatase|nucleoside diphosphate phosphohydrolase activity|type L nucleoside diphosphatase|nucleoside diphosphate phosphatase activity|NDPase activity|apyrase activity|nucleoside 5'-diphosphatase activity|nucleoside diphosphatase activity http://purl.obolibrary.org/obo/GO_0017110 GO:0042170 biolink:CellularComponent plastid membrane Either of the lipid bilayers that surround a plastid and form the plastid envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0042170 GO:0032749 biolink:BiologicalProcess positive regulation of interleukin-25 production Any process that activates or increases the frequency, rate, or extent of interleukin-25 production. go-plus.json up regulation of interleukin-25 production|activation of interleukin-25 production|stimulation of interleukin-25 production|positive regulation of interleukin-25 biosynthetic process|positive regulation of interleukin-25 secretion|up-regulation of interleukin-25 production|upregulation of interleukin-25 production|positive regulation of IL-25 production http://purl.obolibrary.org/obo/GO_0032749 CHEBI:45373 biolink:ChemicalSubstance sulfanilamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_45373 chebi_ph7_3 UBERON:0006909 biolink:AnatomicalEntity lumen of digestive tract An anatomical space that surrounded_by a digestive tract. go-plus.json lumen of alimentary tract|digestive tract lumen|gut lumen|lumen of digestive tract|gut cavity|lumen of gut http://purl.obolibrary.org/obo/UBERON_0006909 GO:0032748 biolink:BiologicalProcess positive regulation of interleukin-24 production Any process that activates or increases the frequency, rate, or extent of interleukin-24 production. go-plus.json up regulation of interleukin-24 production|activation of interleukin-24 production|stimulation of interleukin-24 production|positive regulation of interleukin-24 biosynthetic process|up-regulation of interleukin-24 production|upregulation of interleukin-24 production|positive regulation of IL-24 production http://purl.obolibrary.org/obo/GO_0032748 GO:0042172 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042172 GO:0032747 biolink:BiologicalProcess positive regulation of interleukin-23 production Any process that activates or increases the frequency, rate, or extent of interleukin-23 production. go-plus.json up regulation of interleukin-23 production|activation of interleukin-23 production|stimulation of interleukin-23 production|positive regulation of interleukin-23 biosynthetic process|up-regulation of interleukin-23 production|upregulation of interleukin-23 production|positive regulation of IL-23 production http://purl.obolibrary.org/obo/GO_0032747 UBERON:0006907 biolink:AnatomicalEntity slow muscle tissue The darker-colored muscle tissue of some mammals, composed of slow twitch muscle fibers. go-plus.json red muscle|slow-twitch skeletal muscle|slow muscle|slow skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0006907 GO:0042171 biolink:MolecularActivity lysophosphatidic acid acyltransferase activity Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid. go-plus.json LPAAT activity http://purl.obolibrary.org/obo/GO_0042171 GO:0032746 biolink:BiologicalProcess positive regulation of interleukin-22 production Any process that activates or increases the frequency, rate, or extent of interleukin-22 production. go-plus.json activation of interleukin-22 production|stimulation of interleukin-22 production|positive regulation of interleukin-22 biosynthetic process|up-regulation of interleukin-22 production|upregulation of interleukin-22 production|positive regulation of IL-22 production|up regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0032746 GO:0032745 biolink:BiologicalProcess positive regulation of interleukin-21 production Any process that activates or increases the frequency, rate, or extent of interleukin-21 production. go-plus.json stimulation of interleukin-21 production|positive regulation of interleukin-21 biosynthetic process|up-regulation of interleukin-21 production|upregulation of interleukin-21 production|positive regulation of IL-21 production|up regulation of interleukin-21 production|activation of interleukin-21 production http://purl.obolibrary.org/obo/GO_0032745 UBERON:0006905 biolink:AnatomicalEntity mandibular process mesenchyme Mesenchyme that is part of a mandibular prominence. go-plus.json mesenchyme of mandibular prominence|mesenchyme of mandibular process http://purl.obolibrary.org/obo/UBERON_0006905 GO:0032744 biolink:BiologicalProcess positive regulation of interleukin-20 production Any process that activates or increases the frequency, rate, or extent of interleukin-20 production. go-plus.json stimulation of interleukin-20 production|positive regulation of interleukin-20 biosynthetic process|up-regulation of interleukin-20 production|upregulation of interleukin-20 production|positive regulation of IL-20 production|up regulation of interleukin-20 production|activation of interleukin-20 production http://purl.obolibrary.org/obo/GO_0032744 UBERON:0006904 biolink:AnatomicalEntity head mesenchyme from mesoderm A head mesenchyme that develops_from a mesoderm. go-plus.json mesenchyme derived from head mesoderm|cranial mesoderm|mesenchyme from head mesoderm|head mesenchyme from head mesoderm|head mesenchyme from mesoderm|head mesenchyme derived from mesoderm|head mesoderm http://purl.obolibrary.org/obo/UBERON_0006904 GO:0032743 biolink:BiologicalProcess positive regulation of interleukin-2 production Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. go-plus.json up regulation of interleukin-2 production|positive regulation of interleukin-2 secretion|positive regulation of IL-2 production|positive regulation of interleukin-2 biosynthetic process|upregulation of interleukin-2 production|stimulation of interleukin-2 production|up-regulation of interleukin-2 production|activation of interleukin-2 production http://purl.obolibrary.org/obo/GO_0032743 GO:0042178 biolink:BiologicalProcess xenobiotic catabolic process The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json drug catabolism|exogenous drug degradation|exogenous drug catabolism|exogenous drug breakdown|drug degradation|exogenous drug catabolic process|drug breakdown|xenobiotic catabolism|xenobiotic degradation|drug catabolic process|xenobiotic breakdown http://purl.obolibrary.org/obo/GO_0042178 GO:0042177 biolink:BiologicalProcess negative regulation of protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. go-plus.json down regulation of protein catabolic process|downregulation of protein catabolic process|negative regulation of protein degradation|negative regulation of protein catabolism|negative regulation of protein breakdown|down-regulation of protein catabolic process|inhibition of protein catabolic process http://purl.obolibrary.org/obo/GO_0042177 GO:0042179 biolink:BiologicalProcess nicotine biosynthetic process The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. go-plus.json nicotine anabolism|nicotine synthesis|nicotine formation|nicotine biosynthesis http://purl.obolibrary.org/obo/GO_0042179 GO:0042174 biolink:BiologicalProcess negative regulation of sporulation resulting in formation of a cellular spore Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation. go-plus.json down regulation of sporulation|downregulation of sporulation|down-regulation of sporulation|inhibition of sporulation http://purl.obolibrary.org/obo/GO_0042174 GO:0042173 biolink:BiologicalProcess regulation of sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of spore formation. go-plus.json http://purl.obolibrary.org/obo/GO_0042173 GO:0042176 biolink:BiologicalProcess regulation of protein catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. go-plus.json regulation of protein breakdown|regulation of protein catabolism|regulation of protein degradation http://purl.obolibrary.org/obo/GO_0042176 GO:0042175 biolink:CellularComponent nuclear outer membrane-endoplasmic reticulum membrane network The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. go-plus.json NE-ER network|nuclear membrane-endoplasmic reticulum continuum|nuclear envelope-endoplasmic reticulum continuum|nuclear envelope-ER network|nuclear membrane-ER network|NE-ER continuum|nuclear envelope-endoplasmic reticulum network http://purl.obolibrary.org/obo/GO_0042175 GO:0017127 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017127 GO:0017126 biolink:BiologicalProcess nucleologenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. go-plus.json nucleolus assembly|nucleolus biogenesis http://purl.obolibrary.org/obo/GO_0017126 GO:0017129 biolink:MolecularActivity triglyceride binding Binding to a triester of glycerol. go-plus.json triacylglycerol binding http://purl.obolibrary.org/obo/GO_0017129 GO:0017128 biolink:MolecularActivity phospholipid scramblase activity Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0017128 GO:0017123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017123 GO:0032742 biolink:BiologicalProcess positive regulation of interleukin-19 production Any process that activates or increases the frequency, rate, or extent of interleukin-19 production. go-plus.json positive regulation of IL-19 production|up regulation of interleukin-19 production|activation of interleukin-19 production|stimulation of interleukin-19 production|positive regulation of interleukin-19 biosynthetic process|up-regulation of interleukin-19 production|upregulation of interleukin-19 production http://purl.obolibrary.org/obo/GO_0032742 UBERON:0006913 biolink:AnatomicalEntity lip epithelium An epithelium that is part of a lip. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006913 GO:0017122 biolink:CellularComponent protein N-acetylglucosaminyltransferase complex A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits. go-plus.json O-GlcNAc transferase complex|UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase http://purl.obolibrary.org/obo/GO_0017122 GO:0032741 biolink:BiologicalProcess positive regulation of interleukin-18 production Any process that activates or increases the frequency, rate, or extent of interleukin-18 production. go-plus.json up regulation of interleukin-18 production|activation of interleukin-18 production|positive regulation of interleukin-18 secretion|stimulation of interleukin-18 production|positive regulation of interleukin-18 biosynthetic process|up-regulation of interleukin-18 production|upregulation of interleukin-18 production|positive regulation of IL-18 production http://purl.obolibrary.org/obo/GO_0032741 GO:0017125 biolink:MolecularActivity deoxycytidyl transferase activity Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA. Reactome:R-HSA-110308 go-plus.json deoxycytidyl transferase activity, template-dependent http://purl.obolibrary.org/obo/GO_0017125 GO:0032740 biolink:BiologicalProcess positive regulation of interleukin-17 production Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. go-plus.json positive regulation of CTLA-8 production|up regulation of interleukin-17 production|positive regulation of Cytotoxic T-lymphocyte-associated antigen 8 production|activation of interleukin-17 production|positive regulation of interleukin-17 secretion|stimulation of interleukin-17 production|positive regulation of interleukin-17 biosynthetic process|up-regulation of interleukin-17 production|upregulation of interleukin-17 production|positive regulation of IL-17 production http://purl.obolibrary.org/obo/GO_0032740 GO:0017124 biolink:MolecularActivity SH3 domain binding Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0017124 GO:0017121 biolink:BiologicalProcess plasma membrane phospholipid scrambling The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). go-plus.json phospholipid scrambling|PL scrambling http://purl.obolibrary.org/obo/GO_0017121 GO:0017120 biolink:MolecularActivity obsolete polyphosphatidylinositol phosphatase activity OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization. go-plus.json polyphosphoinositide phosphatase activity|polyphosphatidylinositol phosphatase activity http://purl.obolibrary.org/obo/GO_0017120 GO:0042181 biolink:BiologicalProcess ketone biosynthetic process The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. go-plus.json ketone formation|ketone anabolism|ketone synthesis|ketone biosynthesis http://purl.obolibrary.org/obo/GO_0042181 GO:0032739 biolink:BiologicalProcess positive regulation of interleukin-16 production Any process that activates or increases the frequency, rate, or extent of interleukin-16 production. go-plus.json positive regulation of interleukin-16 biosynthetic process|up-regulation of interleukin-16 production|upregulation of interleukin-16 production|positive regulation of IL-16 production|up regulation of interleukin-16 production|activation of interleukin-16 production|stimulation of interleukin-16 production http://purl.obolibrary.org/obo/GO_0032739 GO:0032738 biolink:BiologicalProcess positive regulation of interleukin-15 production Any process that activates or increases the frequency, rate, or extent of interleukin-15 production. go-plus.json up-regulation of interleukin-15 production|upregulation of interleukin-15 production|positive regulation of IL-15 production|up regulation of interleukin-15 production|activation of interleukin-15 production|stimulation of interleukin-15 production|positive regulation of interleukin-15 biosynthetic process http://purl.obolibrary.org/obo/GO_0032738 GO:0042180 biolink:BiologicalProcess cellular ketone metabolic process The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. go-plus.json ketone metabolism http://purl.obolibrary.org/obo/GO_0042180 goslim_pir GO:0032737 biolink:BiologicalProcess positive regulation of interleukin-14 production Any process that activates or increases the frequency, rate, or extent of interleukin-14 production. go-plus.json up-regulation of interleukin-14 production|upregulation of interleukin-14 production|positive regulation of IL-14 production|up regulation of interleukin-14 production|activation of interleukin-14 production|stimulation of interleukin-14 production|positive regulation of interleukin-14 biosynthetic process http://purl.obolibrary.org/obo/GO_0032737 GO:0042183 biolink:BiologicalProcess formate catabolic process The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. go-plus.json formic acid catabolic process|formate degradation|formic acid catabolism|formate breakdown|formate catabolism http://purl.obolibrary.org/obo/GO_0042183 CHEBI:21398 biolink:ChemicalSubstance L-altraric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21398 GO:0032736 biolink:BiologicalProcess positive regulation of interleukin-13 production Any process that activates or increases the frequency, rate, or extent of interleukin-13 production. go-plus.json up-regulation of interleukin-13 production|upregulation of interleukin-13 production|positive regulation of IL-13 production|up regulation of interleukin-13 production|activation of interleukin-13 production|stimulation of interleukin-13 production|positive regulation of interleukin-13 biosynthetic process|positive regulation of interleukin-13 secretion http://purl.obolibrary.org/obo/GO_0032736 CHEBI:21397 biolink:ChemicalSubstance L-altrarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_21397 GO:0042182 biolink:BiologicalProcess ketone catabolic process The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. go-plus.json ketone degradation|ketone breakdown|ketone catabolism http://purl.obolibrary.org/obo/GO_0042182 GO:0032735 biolink:BiologicalProcess positive regulation of interleukin-12 production Any process that activates or increases the frequency, rate, or extent of interleukin-12 production. go-plus.json upregulation of interleukin-12 production|positive regulation of NKSF production|positive regulation of IL-12 production|up regulation of interleukin-12 production|activation of interleukin-12 production|stimulation of interleukin-12 production|positive regulation of CLMF production|positive regulation of interleukin-12 biosynthetic process|up-regulation of interleukin-12 production|positive regulation of interleukin-12 secretion http://purl.obolibrary.org/obo/GO_0032735 GO:0032734 biolink:BiologicalProcess positive regulation of interleukin-11 production Any process that activates or increases the frequency, rate, or extent of interleukin-11 production. go-plus.json upregulation of interleukin-11 production|positive regulation of IL-11 production|up regulation of interleukin-11 production|activation of interleukin-11 production|stimulation of interleukin-11 production|positive regulation of interleukin-11 biosynthetic process|up-regulation of interleukin-11 production|positive regulation of interleukin-11 secretion http://purl.obolibrary.org/obo/GO_0032734 GO:0032733 biolink:BiologicalProcess positive regulation of interleukin-10 production Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. go-plus.json positive regulation of interleukin-10 secretion|upregulation of interleukin-10 production|positive regulation of IL-10 production|up regulation of interleukin-10 production|activation of interleukin-10 production|stimulation of interleukin-10 production|positive regulation of interleukin-10 biosynthetic process|up-regulation of interleukin-10 production http://purl.obolibrary.org/obo/GO_0032733 GO:0032732 biolink:BiologicalProcess positive regulation of interleukin-1 production Any process that activates or increases the frequency, rate, or extent of interleukin-1 production. go-plus.json upregulation of interleukin-1 production|stimulation of interleukin-1 production|up-regulation of interleukin-1 production|activation of interleukin-1 production|up regulation of interleukin-1 production|positive regulation of interleukin-1 secretion|positive regulation of IL-1 production|positive regulation of interleukin-1 biosynthetic process http://purl.obolibrary.org/obo/GO_0032732 GO:0042189 biolink:BiologicalProcess vanillin biosynthetic process The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods. go-plus.json vanillin biosynthesis|vanillin synthesis|vanillin formation|vanillic aldehyde biosynthesis|vanillic aldehyde biosynthetic process|vanillin anabolism http://purl.obolibrary.org/obo/GO_0042189 GO:0042188 biolink:BiologicalProcess 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. go-plus.json 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolism|DDT catabolism|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane degradation|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane breakdown|DDT catabolic process http://purl.obolibrary.org/obo/GO_0042188 GO:0042185 biolink:BiologicalProcess m-xylene catabolic process The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon. MetaCyc:PWY-142 go-plus.json m-xylene catabolism|m-xylene degradation|meta-xylene catabolism|meta-xylene catabolic process|m-xylene breakdown http://purl.obolibrary.org/obo/GO_0042185 GO:0042184 biolink:BiologicalProcess xylene catabolic process The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. go-plus.json xylene catabolism|xylene degradation|xylene breakdown http://purl.obolibrary.org/obo/GO_0042184 GO:0042187 biolink:BiologicalProcess p-xylene catabolic process The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon. go-plus.json para-xylene catabolic process|p-xylene degradation|para-xylene catabolism|p-xylene breakdown|p-xylene catabolism http://purl.obolibrary.org/obo/GO_0042187 GO:0042186 biolink:BiologicalProcess o-xylene catabolic process The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. go-plus.json o-xylene degradation|o-xylene breakdown|ortho-xylene catabolism|ortho-xylene catabolic process|o-xylene catabolism http://purl.obolibrary.org/obo/GO_0042186 GO:0032731 biolink:BiologicalProcess positive regulation of interleukin-1 beta production Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. go-plus.json upregulation of interleukin-1 beta production|positive regulation of IL-1 beta production|up regulation of interleukin-1 beta production|activation of interleukin-1 beta production|stimulation of interleukin-1 beta production|positive regulation of interleukin-1 beta biosynthetic process|up-regulation of interleukin-1 beta production|positive regulation of interleukin-1 beta secretion http://purl.obolibrary.org/obo/GO_0032731 GO:0032730 biolink:BiologicalProcess positive regulation of interleukin-1 alpha production Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production. go-plus.json stimulation of interleukin-1 alpha production|up-regulation of interleukin-1 alpha production|activation of interleukin-1 alpha production|up regulation of interleukin-1 alpha production|positive regulation of IL-1 alpha production|positive regulation of interleukin-1 alpha biosynthetic process|upregulation of interleukin-1 alpha production|positive regulation of interleukin-1 alpha secretion http://purl.obolibrary.org/obo/GO_0032730 GO:0032728 biolink:BiologicalProcess positive regulation of interferon-beta production Any process that activates or increases the frequency, rate, or extent of interferon-beta production. go-plus.json positive regulation of interferon-beta biosynthetic process|upregulation of interferon-beta production|stimulation of interferon-beta production|up-regulation of interferon-beta production|activation of interferon-beta production|positive regulation of IFN-beta production|up regulation of interferon-beta production|positive regulation of interferon-beta secretion http://purl.obolibrary.org/obo/GO_0032728 GO:0042192 biolink:BiologicalProcess methylmercury biosynthetic process The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal. go-plus.json methylmercury synthesis|methylmercury formation|methylmercury biosynthesis|methylmercury anabolism http://purl.obolibrary.org/obo/GO_0042192 GO:0042191 biolink:BiologicalProcess methylmercury metabolic process The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species. go-plus.json methylmercury metabolism http://purl.obolibrary.org/obo/GO_0042191 GO:0032727 biolink:BiologicalProcess positive regulation of interferon-alpha production Any process that activates or increases the frequency, rate, or extent of interferon-alpha production. go-plus.json upregulation of interferon-alpha production|positive regulation of interferon-alpha secretion|up regulation of interferon-alpha production|activation of interferon-alpha production|stimulation of interferon-alpha production|positive regulation of interferon-alpha biosynthetic process|up-regulation of interferon-alpha production http://purl.obolibrary.org/obo/GO_0032727 GO:0032726 biolink:BiologicalProcess positive regulation of hepatocyte growth factor production Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production. go-plus.json stimulation of hepatocyte growth factor production|positive regulation of hepatocyte growth factor biosynthetic process|up-regulation of hepatocyte growth factor production|upregulation of hepatocyte growth factor production|positive regulation of scatter factor production|positive regulation of HGF production|up regulation of hepatocyte growth factor production|activation of hepatocyte growth factor production http://purl.obolibrary.org/obo/GO_0032726 GO:0042194 biolink:BiologicalProcess quinate biosynthetic process The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid. go-plus.json quinate biosynthesis|quinate anabolism|quinate synthesis|quinate formation|quinic acid biosynthesis|quinic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0042194 GO:0032725 biolink:BiologicalProcess positive regulation of granulocyte macrophage colony-stimulating factor production Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. go-plus.json up regulation of granulocyte macrophage colony-stimulating factor production|activation of granulocyte macrophage colony-stimulating factor production|stimulation of granulocyte macrophage colony-stimulating factor production|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|up-regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of GM-CSF production|positive regulation of granulocyte macrophage colony stimulating factor production|upregulation of granulocyte macrophage colony-stimulating factor production http://purl.obolibrary.org/obo/GO_0032725 GO:0042193 biolink:BiologicalProcess methylmercury catabolic process The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal. go-plus.json methylmercury catabolism|methylmercury degradation|methylmercury breakdown http://purl.obolibrary.org/obo/GO_0042193 GO:0032724 biolink:BiologicalProcess positive regulation of fractalkine production Any process that activates or increases the frequency, rate, or extent of fractalkine production. go-plus.json upregulation of fractalkine production|stimulation of fractalkine production|activation of fractalkine production|up-regulation of fractalkine production|up regulation of fractalkine production http://purl.obolibrary.org/obo/GO_0032724 GO:0032723 biolink:BiologicalProcess positive regulation of connective tissue growth factor production Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production. go-plus.json stimulation of connective tissue growth factor production|up-regulation of connective tissue growth factor production|activation of connective tissue growth factor production|positive regulation of Fisp12 production|positive regulation of IGFBP8 production|positive regulation of CCN2 production|positive regulation of Hcs24 production|up regulation of connective tissue growth factor production|positive regulation of hypertrophic chondrocyte-specific gene product 24 production|positive regulation of CTGF production|positive regulation of connective tissue growth factor biosynthetic process|upregulation of connective tissue growth factor production http://purl.obolibrary.org/obo/GO_0032723 GO:0042190 biolink:BiologicalProcess vanillin catabolic process The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods. go-plus.json vanillin catabolism|vanillic aldehyde catabolic process|vanillin degradation|vanillic aldehyde catabolism|vanillin breakdown http://purl.obolibrary.org/obo/GO_0042190 GO:0032722 biolink:BiologicalProcess positive regulation of chemokine production Any process that activates or increases the frequency, rate, or extent of chemokine production. go-plus.json positive regulation of chemokine secretion|up regulation of chemokine production|positive regulation of chemokine biosynthetic process|upregulation of chemokine production|stimulation of chemokine production|activation of chemokine production|up-regulation of chemokine production http://purl.obolibrary.org/obo/GO_0032722 GO:0032721 biolink:BiologicalProcess negative regulation of lymphotoxin A production Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production. go-plus.json negative regulation of lymphotoxin A biosynthetic process|downregulation of lymphotoxin A production|negative regulation of LTA production|down regulation of lymphotoxin A production|inhibition of lymphotoxin A production|negative regulation of lymphotoxin-alpha production|down-regulation of lymphotoxin A production|negative regulation of TNF-beta production|negative regulation of tumor necrosis factor-beta production http://purl.obolibrary.org/obo/GO_0032721 GO:0042199 biolink:BiologicalProcess cyanuric acid metabolic process The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives. go-plus.json cyanuric acid metabolism http://purl.obolibrary.org/obo/GO_0042199 GO:0042196 biolink:BiologicalProcess chlorinated hydrocarbon metabolic process The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms. go-plus.json chlorinated hydrocarbon metabolism http://purl.obolibrary.org/obo/GO_0042196 GO:0042195 biolink:BiologicalProcess aerobic gallate catabolic process The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen. go-plus.json aerobic gallic acid catabolism|aerobic gallic acid catabolic process|aerobic gallate catabolism|aerobic gallate degradation|aerobic gallate breakdown http://purl.obolibrary.org/obo/GO_0042195 GO:0042198 biolink:BiologicalProcess nylon metabolic process The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids. go-plus.json nylon metabolism http://purl.obolibrary.org/obo/GO_0042198 GO:0032729 biolink:BiologicalProcess positive regulation of interferon-gamma production Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. go-plus.json positive regulation of interferon-gamma secretion|positive regulation of interferon-gamma biosynthetic process|positive regulation of type II interferon production|up-regulation of interferon-gamma production|upregulation of interferon-gamma production|up regulation of interferon-gamma production|activation of interferon-gamma production|stimulation of interferon-gamma production http://purl.obolibrary.org/obo/GO_0032729 GO:0042197 biolink:BiologicalProcess halogenated hydrocarbon metabolic process The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine. go-plus.json halogenated hydrocarbon metabolism http://purl.obolibrary.org/obo/GO_0042197 GO:0017109 biolink:CellularComponent glutamate-cysteine ligase complex An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine. go-plus.json gamma-glutamylcysteine synthetase complex http://purl.obolibrary.org/obo/GO_0017109 GO:0017108 biolink:MolecularActivity 5'-flap endonuclease activity Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Reactome:R-HSA-174441|Reactome:R-HSA-69152|Reactome:R-HSA-5651782|Reactome:R-HSA-5687664|Reactome:R-HSA-110363|Reactome:R-HSA-174446 go-plus.json 5' flap endonuclease activity http://purl.obolibrary.org/obo/GO_0017108 CHEBI:59991 biolink:ChemicalSubstance 4-(hydroxylamino)-N,N-dimethylaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_59991 chebi_ph7_3 CHEBI:59990 biolink:ChemicalSubstance N,N-dimethyl-4-nitrosoaniline go-plus.json http://purl.obolibrary.org/obo/CHEBI_59990 chebi_ph7_3 GO:0017105 biolink:MolecularActivity acyl-CoA delta11-desaturase activity Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O. The enzyme introduces a cis double bond at position C-11 of saturated fatty acyl-CoAs. EC:1.14.19.5 go-plus.json acyl-CoA delta(11)-desaturase activity|acyl-CoA D11-desaturase activity http://purl.obolibrary.org/obo/GO_0017105 GO:0017104 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017104 GO:0017107 biolink:MolecularActivity obsolete anion exchanger adaptor activity OBSOLETE. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way. go-plus.json http://purl.obolibrary.org/obo/GO_0017107 GO:0017106 biolink:MolecularActivity obsolete activin inhibitor activity OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone. go-plus.json activin inhibitor activity http://purl.obolibrary.org/obo/GO_0017106 GO:0032720 biolink:BiologicalProcess negative regulation of tumor necrosis factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. go-plus.json downregulation of tumor necrosis factor production|inhibition of cachectin production|down regulation of tumor necrosis factor production|inhibition of tumor necrosis factor production|negative regulation TNF production|down-regulation of tumor necrosis factor production|negative regulation of tumor necrosis factor secretion|negative regulation tumor necrosis factor-alpha production|negative regulation TNF-alpha production|negative regulation of tumor necrosis factor biosynthetic process http://purl.obolibrary.org/obo/GO_0032720 GO:0017101 biolink:CellularComponent aminoacyl-tRNA synthetase multienzyme complex A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates. go-plus.json multisynthetase complex|aminoacyl-tRNA synthetase complex http://purl.obolibrary.org/obo/GO_0017101 GO:0017100 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017100 GO:0017103 biolink:MolecularActivity UTP:galactose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose. EC:2.7.7.10|MetaCyc:UTPHEXPURIDYLYLTRANS-RXN|KEGG_REACTION:R00502|RHEA:14209 go-plus.json alpha-D-galactose 1-phosphate uridylyltransferase activity|galactose 1-phosphate uridyltransferase activity|UTP:hexose-1-phosphate uridylyltransferase activity|UTP-hexose-1-phosphate uridylyltransferase activity|UDPgalactose pyrophosphorylase activity|uridine diphosphate galactose pyrophosphorylase activity|UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity|uridine diphosphogalactose pyrophosphorylase activity|galactose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|galactose 1-phosphate uridylyltransferase activity http://purl.obolibrary.org/obo/GO_0017103 CHEBI:59999 biolink:ChemicalSubstance chemical substance go-plus.json http://purl.obolibrary.org/obo/CHEBI_59999 GO:0017102 biolink:CellularComponent methionyl glutamyl tRNA synthetase complex A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers. go-plus.json http://purl.obolibrary.org/obo/GO_0017102 CHEBI:59998 biolink:ChemicalSubstance 1,2-diacyl-sn-glycerol 3-diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59998 CHEBI:59997 biolink:ChemicalSubstance EC 1.14.18.1 (tyrosinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_59997 CHEBI:59996 biolink:ChemicalSubstance 1,2-diacyl-sn-glycerol 3-diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59996 chebi_ph7_3 CHEBI:84949 biolink:ChemicalSubstance (11E)-Delta(11)-fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84949 chebi_ph7_3 CHEBI:84948 biolink:ChemicalSubstance 11,12-saturated fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84948 chebi_ph7_3 CHEBI:84947 biolink:ChemicalSubstance (11Z)-Delta(11)-fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84947 chebi_ph7_3 CHEBI:84940 biolink:ChemicalSubstance ethyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84940 chebi_ph7_3 CHEBI:60980 biolink:ChemicalSubstance beta-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_60980 CHEBI:60982 biolink:ChemicalSubstance methyl galactoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_60982 CHEBI:60981 biolink:ChemicalSubstance UDP-rhamnose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60981 chebi_ph7_3 OBO:GOCHE_24621 biolink:OntologyClass substance with hormone role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24621 3_STAR CHEBI:137097 biolink:ChemicalSubstance 9-(octadecanoyloxy)octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137097 CHEBI:84955 biolink:ChemicalSubstance 7-demethylmitomycin A(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84955 chebi_ph7_3 CHEBI:84952 biolink:ChemicalSubstance 7-demethylmitomycin B(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84952 chebi_ph7_3 CHEBI:60991 biolink:ChemicalSubstance 2-hydroxyethylphosphonic acid(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60991 chebi_ph7_3 CHEBI:60997 biolink:ChemicalSubstance (2R)-3-sulfopropanediol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60997 chebi_ph7_3 CHEBI:60996 biolink:ChemicalSubstance (2R)-3-sulfopropanediol go-plus.json http://purl.obolibrary.org/obo/CHEBI_60996 CHEBI:70315 biolink:ChemicalSubstance eburicol go-plus.json http://purl.obolibrary.org/obo/CHEBI_70315 chebi_ph7_3 GO:0140409 biolink:BiologicalProcess positive regulation of mRNA alternative polyadenylation Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation. go-plus.json http://purl.obolibrary.org/obo/GO_0140409 GO:0140408 biolink:BiologicalProcess regulation of mRNA alternative polyadenylation Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation. go-plus.json http://purl.obolibrary.org/obo/GO_0140408 CHEBI:137084 biolink:ChemicalSubstance 9-[(9Z)-hexadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137084 CHEBI:137083 biolink:ChemicalSubstance 13-[(9Z)-octadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137083 CHEBI:137082 biolink:ChemicalSubstance 12-[(9Z)-octadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137082 CHEBI:84969 biolink:ChemicalSubstance cholesteryl (5Z,8Z,11Z,14Z,17Z-eicosapentaenoate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84969 chebi_ph7_3 CHEBI:84968 biolink:ChemicalSubstance 1,2-dipalmitoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84968 chebi_ph7_3 GO:0140403 biolink:BiologicalProcess effector-mediated suppression of host innate immune response A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json effector-dependent suppression of host immune innate response by symbiont|effector-mediated suppression of host immune innate response by symbiont|effector triggered suppression of host immune innate response by symbiont|effector dependent suppression of host immune innate response by symbiont|effector-mediated suppression of host innate immunity|effector-mediated suppression of host innate immune response by symbiont|effector-triggered suppression of host immune innate response by symbiont http://purl.obolibrary.org/obo/GO_0140403 CHEBI:84966 biolink:ChemicalSubstance ipsdienone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84966 chebi_ph7_3 GO:0140405 biolink:BiologicalProcess spindle pole body-led chromosome movement during mitotic interphase A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase. go-plus.json http://purl.obolibrary.org/obo/GO_0140405 GO:0140404 biolink:BiologicalProcess effector-mediated modulation of host innate immune response by symbiont A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json effector mediated modulation of host immune response by symbiont|effector-triggered modulation of host immune response by symbiont|effector-dependent modulation of host immune response by symbiont|effector triggered modulation of host immune response by symbiont|effector-mediated modulation of host immunity http://purl.obolibrary.org/obo/GO_0140404 CHEBI:84963 biolink:ChemicalSubstance 13-hydroxy-gamma-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84963 chebi_ph7_3 GO:0140407 biolink:MolecularActivity L-alanine:proton antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out). go-plus.json http://purl.obolibrary.org/obo/GO_0140407 CHEBI:84962 biolink:ChemicalSubstance 13-hydroxy-alpha-tocopherol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84962 chebi_ph7_3 GO:0140406 biolink:BiologicalProcess L-alanine export across the plasma membrane The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json http://purl.obolibrary.org/obo/GO_0140406 NCBITaxon:235629 biolink:OrganismalEntity Acalyphoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_235629 CHEBI:137077 biolink:ChemicalSubstance 2beta-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137077 chebi_ph7_3 CHEBI:137076 biolink:ChemicalSubstance 1beta-hydroxytestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137076 chebi_ph7_3 CHEBI:137091 biolink:ChemicalSubstance 13-(octadecanoyloxy)octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137091 CHEBI:84976 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/22:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84976 CHEBI:84975 biolink:ChemicalSubstance acarbose 7(IV)-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84975 chebi_ph7_3 CHEBI:84973 biolink:ChemicalSubstance oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84973 chebi_ph7_3 CHEBI:84971 biolink:ChemicalSubstance (2E,6E,10E)-geranylgeranic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84971 CHEBI:84970 biolink:ChemicalSubstance (4R)-ipsdienol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84970 chebi_ph7_3 NCBITaxon:441771 biolink:OrganismalEntity Clostridium botulinum A str. Hall go-plus.json Clostridium botulinum A strain Hall http://purl.obolibrary.org/obo/NCBITaxon_441771 CHEBI:137086 biolink:ChemicalSubstance 13-[(9Z)-hexadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137086 CHEBI:137085 biolink:ChemicalSubstance 12-[(9Z)-hexadecenoyloxy]octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137085 NCBITaxon:235631 biolink:OrganismalEntity Crotonoideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_235631 CHEBI:137089 biolink:ChemicalSubstance 12-(octadecanoyloxy)octadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137089 CHEBI:137062 biolink:ChemicalSubstance 7-oxo-5alpha-cholestan-3beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137062 chebi_ph7_3 CHEBI:137061 biolink:ChemicalSubstance cholesta-5,7-dien-3beta,24S-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137061 chebi_ph7_3 CHEBI:84985 biolink:ChemicalSubstance (2E,6E,10E)-omega-hydroxyfarnesyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84985 CHEBI:84984 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/24:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84984 CHEBI:84981 biolink:ChemicalSubstance 2-aminoadipate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84981 GO:0017199 biolink:BiologicalProcess N-terminal peptidyl-threonine acetylation The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase. RESID:AA0052 go-plus.json http://purl.obolibrary.org/obo/GO_0017199 CHEBI:137053 biolink:ChemicalSubstance (24Z),26-hydroxydesmosterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137053 chebi_ph7_3 GO:0017196 biolink:BiologicalProcess N-terminal peptidyl-methionine acetylation The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine. RESID:AA0049 go-plus.json http://purl.obolibrary.org/obo/GO_0017196 GO:0017195 biolink:BiologicalProcess N-terminal peptidyl-lysine N2-acetylation The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed. RESID:AA0048 go-plus.json http://purl.obolibrary.org/obo/GO_0017195 CHEBI:137057 biolink:ChemicalSubstance cholesta-5,7-dien-3beta,25-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137057 chebi_ph7_3 GO:0017198 biolink:BiologicalProcess N-terminal peptidyl-serine acetylation The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine. RESID:AA0051 go-plus.json http://purl.obolibrary.org/obo/GO_0017198 GO:0017197 biolink:BiologicalProcess N-terminal peptidyl-proline acetylation The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline. RESID:AA0050 go-plus.json http://purl.obolibrary.org/obo/GO_0017197 CHEBI:84996 biolink:ChemicalSubstance 3-oxopropanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84996 chebi_ph7_3 CHEBI:84995 biolink:ChemicalSubstance 3-hydroxy-3-(methylthio)propanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84995 chebi_ph7_3 CHEBI:84994 biolink:ChemicalSubstance 3-(methylthio)acryloyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84994 chebi_ph7_3 CHEBI:84992 biolink:ChemicalSubstance 3-methylpalmitoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84992 CHEBI:84991 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/24:2) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84991 CHEBI:84990 biolink:ChemicalSubstance gamma-carboxy-L-glutamate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_84990 chebi_ph7_3 CHEBI:137063 biolink:ChemicalSubstance cholestanol 7alpha,8alpha-epoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_137063 chebi_ph7_3 GO:0017181 biolink:BiologicalProcess peptidyl-diphthine catabolic process The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue. go-plus.json peptidyl-diphthine degradation|peptidyl-diphthine breakdown|peptidyl-diphthine catabolism http://purl.obolibrary.org/obo/GO_0017181 GO:0017180 biolink:BiologicalProcess peptidyl-diphthine biosynthetic process from peptidyl-histidine The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine. go-plus.json peptidyl-diphthine anabolism from peptidyl-histidine|peptidyl-diphthine synthesis from peptidyl-histidine|peptidyl-diphthine formation from peptidyl-histidine http://purl.obolibrary.org/obo/GO_0017180 GO:0017183 biolink:BiologicalProcess peptidyl-diphthamide biosynthetic process from peptidyl-histidine The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria. RESID:AA0040 go-plus.json peptidyl-diphthamide anabolism from peptidyl-histidine|peptidyl-diphthamide synthesis from peptidyl-histidine|peptidyl-diphthamide formation from peptidyl-histidine http://purl.obolibrary.org/obo/GO_0017183 GO:0017182 biolink:BiologicalProcess peptidyl-diphthamide metabolic process The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue. go-plus.json peptidyl-diphthamide metabolism http://purl.obolibrary.org/obo/GO_0017182 CHEBI:137040 biolink:ChemicalSubstance short chain fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137040 chebi_ph7_3 GO:0042101 biolink:CellularComponent T cell receptor complex A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. Wikipedia:T_cell_receptor go-plus.json T lymphocyte receptor complex|TCR complex|TCR|T-lymphocyte receptor complex|T-cell receptor complex http://purl.obolibrary.org/obo/GO_0042101 GO:0042100 biolink:BiologicalProcess B cell proliferation The expansion of a B cell population by cell division. Follows B cell activation. go-plus.json B lymphocyte proliferation|B-cell proliferation|B-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0042100 GO:0042103 biolink:BiologicalProcess positive regulation of T cell homeostatic proliferation Any process that activates or increases the rate or extent of resting T cell proliferation. go-plus.json upregulation of T cell homeostatic proliferation|positive regulation of resting T cell proliferation|positive regulation of T-cell homeostatic proliferation|stimulation of T cell homeostatic proliferation|up-regulation of T cell homeostatic proliferation|activation of T cell homeostatic proliferation|positive regulation of T-lymphocyte homeostatic proliferation|up regulation of T cell homeostatic proliferation|positive regulation of T lymphocyte homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042103 GO:0042102 biolink:BiologicalProcess positive regulation of T cell proliferation Any process that activates or increases the rate or extent of T cell proliferation. go-plus.json upregulation of T cell proliferation|stimulation of T cell proliferation|activation of T cell proliferation|up-regulation of T cell proliferation|positive regulation of T-lymphocyte proliferation|up regulation of T cell proliferation|positive regulation of T lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0042102 GO:0042109 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042109 GO:0042108 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042108 CHEBI:137039 biolink:ChemicalSubstance 8,9-epoxy-(5Z,11Z,14Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137039 GO:0042105 biolink:CellularComponent alpha-beta T cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein. go-plus.json alpha-beta T lymphocyte receptor complex|alpha-beta T-lymphocyte receptor complex|alpha-beta TCR complex|alpha-beta T-cell receptor complex http://purl.obolibrary.org/obo/GO_0042105 GO:0042104 biolink:BiologicalProcess positive regulation of activated T cell proliferation Any process that activates or increases the rate or extent of activated T cell proliferation. go-plus.json activation of activated T cell proliferation|up-regulation of activated T cell proliferation|positive regulation of activated T-lymphocyte proliferation|up regulation of activated T cell proliferation|positive regulation of activated T lymphocyte proliferation|upregulation of activated T cell proliferation|stimulation of activated T cell proliferation|positive regulation of activated T-cell proliferation http://purl.obolibrary.org/obo/GO_0042104 GO:0042107 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042107 GO:0042106 biolink:CellularComponent gamma-delta T cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein. go-plus.json gamma-delta T-lymphocyte receptor complex|gamma-delta TCR complex|gamma-delta T-cell receptor complex|gamma-delta T lymphocyte receptor complex http://purl.obolibrary.org/obo/GO_0042106 GO:0017178 biolink:MolecularActivity diphthine-ammonia ligase activity Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate. RHEA:19753|MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN|EC:6.3.1.14|KEGG_REACTION:R03613|Reactome:R-HSA-5358475 go-plus.json diphthine:ammonia ligase (ADP-forming)|diphthamide synthase activity|diphthamide synthetase activity http://purl.obolibrary.org/obo/GO_0017178 CHEBI:137033 biolink:ChemicalSubstance N,N-dihydroxy-L-hexahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137033 GO:0017177 biolink:CellularComponent glucosidase II complex A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins. go-plus.json alpha-glucosidase II complex http://purl.obolibrary.org/obo/GO_0017177 CHEBI:137032 biolink:ChemicalSubstance 19-oxo-5alpha-dihydrotestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137032 chebi_ph7_3 CHEBI:137031 biolink:ChemicalSubstance 19-hydroxy-5alpha-dihydrotestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137031 chebi_ph7_3 GO:0017179 biolink:BiologicalProcess peptidyl-diphthine metabolic process The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue. go-plus.json peptidyl-diphthine metabolism http://purl.obolibrary.org/obo/GO_0017179 CHEBI:137030 biolink:ChemicalSubstance N,N-dihydroxy-L-pentahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137030 GO:0017174 biolink:MolecularActivity glycine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine. Reactome:R-HSA-6798317|EC:2.1.1.156|MetaCyc:2.1.1.162-RXN|EC:2.1.1.162|MetaCyc:GLYCINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.20|KEGG_REACTION:R00367|RHEA:19937 go-plus.json GNMT|S-adenosyl-L-methionine:glycine methyltransferase activity|S-adenosyl-L-methionine:glycine N-methyltransferase activity|glycine methyltransferase activity http://purl.obolibrary.org/obo/GO_0017174 CHEBI:137037 biolink:ChemicalSubstance 18-hydroxy-5alpha-dihydrotestosterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137037 chebi_ph7_3 GO:0017173 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017173 GO:0017176 biolink:MolecularActivity phosphatidylinositol N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol. MetaCyc:2.4.1.198-RXN|EC:2.4.1.198|RHEA:14789 go-plus.json UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity|UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0017176 GO:0017175 biolink:MolecularActivity obsolete IMP-GMP specific 5'-nucleotidase activity OBSOLETE. Catalysis of the conversion of 5'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5'-ribonucleotides and H2O as a nucleophile. go-plus.json IMP-GMP specific 5'-nucleotidase activity http://purl.obolibrary.org/obo/GO_0017175 GO:0017192 biolink:BiologicalProcess N-terminal peptidyl-glutamine acetylation The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable. RESID:AA0045 go-plus.json http://purl.obolibrary.org/obo/GO_0017192 GO:0017191 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0017191 GO:0017194 biolink:BiologicalProcess N-terminal peptidyl-isoleucine acetylation The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed. RESID:AA0047 go-plus.json http://purl.obolibrary.org/obo/GO_0017194 GO:0017193 biolink:BiologicalProcess N-terminal peptidyl-glycine acetylation The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine. RESID:AA0046 go-plus.json http://purl.obolibrary.org/obo/GO_0017193 CHEBI:137050 biolink:ChemicalSubstance 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137050 GO:0017190 biolink:BiologicalProcess N-terminal peptidyl-aspartic acid acetylation The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase. RESID:AA0042 go-plus.json http://purl.obolibrary.org/obo/GO_0017190 GO:0042112 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042112 GO:0042111 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042111 GO:0042114 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042114 GO:0042113 biolink:BiologicalProcess B cell activation The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json B lymphocyte activation|B-lymphocyte activation|B-cell activation http://purl.obolibrary.org/obo/GO_0042113 GO:0042110 biolink:BiologicalProcess T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json T lymphocyte activation|T-lymphocyte activation|T-cell activation http://purl.obolibrary.org/obo/GO_0042110 GO:0042119 biolink:BiologicalProcess neutrophil activation The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0042119 CHEBI:137049 biolink:ChemicalSubstance 16alpha,17alpha-dihydroxypregnenolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137049 chebi_ph7_3 GO:0042116 biolink:BiologicalProcess macrophage activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json macrophage polarization http://purl.obolibrary.org/obo/GO_0042116 GO:0042115 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042115 GO:0042118 biolink:BiologicalProcess endothelial cell activation The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0042118 GO:0042117 biolink:BiologicalProcess monocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0042117 GO:0017189 biolink:BiologicalProcess N-terminal peptidyl-alanine acetylation The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase. RESID:AA0041 go-plus.json http://purl.obolibrary.org/obo/GO_0017189 CHEBI:137044 biolink:ChemicalSubstance N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137044 GO:0017188 biolink:MolecularActivity aspartate N-acetyltransferase activity Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+). Reactome:R-HSA-8954468|EC:2.3.1.17|MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R00487|RHEA:14165 go-plus.json L-aspartate N-acetyltransferase activity|aspartate acetyltransferase activity|acetyl-CoA:L-aspartate N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0017188 CHEBI:137043 biolink:ChemicalSubstance N-[(+)-7-isojasmonyl]-L-isoleucine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137043 CHEBI:137041 biolink:ChemicalSubstance quinine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137041 chebi_ph7_3 GO:0017185 biolink:BiologicalProcess peptidyl-lysine hydroxylation The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine. go-plus.json http://purl.obolibrary.org/obo/GO_0017185 GO:0017184 biolink:BiologicalProcess peptidyl-diphthamide catabolic process The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue. go-plus.json peptidyl-diphthamide degradation|peptidyl-diphthamide catabolism|peptidyl-diphthamide breakdown http://purl.obolibrary.org/obo/GO_0017184 CHEBI:137047 biolink:ChemicalSubstance 11,12-epoxy-(5Z,8Z,14Z)-icosatrienoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137047 GO:0017187 biolink:BiologicalProcess peptidyl-glutamic acid carboxylation The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase. RESID:AA0032 go-plus.json http://purl.obolibrary.org/obo/GO_0017187 CHEBI:137046 biolink:ChemicalSubstance 6beta,16alpha,17alpha-trihydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_137046 chebi_ph7_3 GO:0017186 biolink:BiologicalProcess peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase. RESID:AA0031 go-plus.json 2-pyrrolidone-5-carboxylic acid biosynthesis|2-pyrrolidone-5-carboxylic acid biosynthetic process|peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase http://purl.obolibrary.org/obo/GO_0017186 CHEBI:59908 biolink:ChemicalSubstance ecgoninium methyl ester(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59908 chebi_ph7_3 CHEBI:59907 biolink:ChemicalSubstance F420-0(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59907 chebi_ph7_3 CHEBI:59906 biolink:ChemicalSubstance 2-phosphonato-L-lactate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59906 chebi_ph7_3 CHEBI:59905 biolink:ChemicalSubstance dopaminium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59905 chebi_ph7_3 CHEBI:59904 biolink:ChemicalSubstance 7,8-didemethyl-8-hydroxy-5-deazariboflavin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59904 chebi_ph7_3 CHEBI:59903 biolink:ChemicalSubstance thermosperminium(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59903 chebi_ph7_3 GO:0140467 biolink:BiologicalProcess integrated stress response signaling The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery. Wikipedia:Integrated_stress_response go-plus.json ISR http://purl.obolibrary.org/obo/GO_0140467 CHEBI:35935 biolink:ChemicalSubstance pent-4-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35935 chebi_ph7_3 GO:0140466 biolink:BiologicalProcess iron-sulfur cluster export from the mitochondrion The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140466 GO:0140469 biolink:BiologicalProcess GCN2-mediated signaling A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation. go-plus.json regulation of eIF2 alpha phosphorylation by amino acid starvation|EIF2AK4-mediated signaling http://purl.obolibrary.org/obo/GO_0140469 GO:0140468 biolink:BiologicalProcess HRI-mediated signaling A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock. go-plus.json EIF2AK1-mediated signaling http://purl.obolibrary.org/obo/GO_0140468 CHEBI:35936 biolink:ChemicalSubstance pent-4-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35936 GO:0140461 biolink:BiologicalProcess obsolete subtelomeric heterochromatin organization OBSOLETE. The organization of chromatin into heterochromatin at the subtelomeric region of a chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0140461 GO:0140460 biolink:BiologicalProcess response to Gram-negative bacterium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium. go-plus.json http://purl.obolibrary.org/obo/GO_0140460 GO:0140463 biolink:MolecularActivity chromatin-protein adaptor The binding activity of a molecule that brings together a protein or a protein complex with a nucleosome, to establish or maintain the chromatin localization of the protein, or protein complex. go-plus.json protein-chromatin adaptor activity|chromatin adaptor|chromatin adaptor activity|chromatin recruitment|chromatin receptor http://purl.obolibrary.org/obo/GO_0140463 CHEBI:35931 biolink:ChemicalSubstance delta-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35931 GO:0140462 biolink:BiologicalProcess pericentric heterochromatin organization The organization of chromatin into heterochromatin at the pericentric region of a chromosome. go-plus.json http://purl.obolibrary.org/obo/GO_0140462 GO:0140464 biolink:BiologicalProcess silent mating-type cassette heterochromatin organization The organization of chromatin into heterochromatin at a silent mating-type cassette locus. go-plus.json http://purl.obolibrary.org/obo/GO_0140464 CHEBI:35932 biolink:ChemicalSubstance 3-methyl-2-oxovaleric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35932 CHEBI:60904 biolink:ChemicalSubstance 4-hydroxy-L-threonine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60904 chebi_ph7_3 CHEBI:60903 biolink:ChemicalSubstance N-(4-aminobenzoyl)-L-glutamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60903 chebi_ph7_3 CHEBI:60908 biolink:ChemicalSubstance (2R)-2-hydroxy-2-methylbutanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_60908 chebi_ph7_3 CHEBI:60907 biolink:ChemicalSubstance (S)-ethylmalonyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_60907 NCBITaxon:8509 biolink:OrganismalEntity Squamata go-plus.json squamates http://purl.obolibrary.org/obo/NCBITaxon_8509 CHEBI:60909 biolink:ChemicalSubstance (S)-ethylmalonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60909 chebi_ph7_3 NCBITaxon:8504 biolink:OrganismalEntity Lepidosauria go-plus.json Reptilia|lepidosaurs|reptiles|lizards http://purl.obolibrary.org/obo/NCBITaxon_8504 GO:0140456 biolink:BiologicalProcess initial meiotic spindle pole body separation The release of duplicated meiotic spindle pole bodies (SPBs). go-plus.json initial spindle pole body separation involved in meiosis I|meiotic spindle pole body duplication http://purl.obolibrary.org/obo/GO_0140456 GO:0140455 biolink:BiologicalProcess cytoplasm protein quality control The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. go-plus.json http://purl.obolibrary.org/obo/GO_0140455 CHEBI:11955 biolink:ChemicalSubstance 4-amino-3-hydroxybutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11955 GO:0140458 biolink:BiologicalProcess pre-transcriptional gene silencing by RNA Any gene inactivation (silencing) process mediated by small RNA molecules that occur before the trancription begins. go-plus.json http://purl.obolibrary.org/obo/GO_0140458 GO:0140457 biolink:MolecularActivity protein demethylase activity Catalysis of the removal of a methyl group from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140457 GO:0140459 biolink:BiologicalProcess response to Gram-positive bacterium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium. go-plus.json http://purl.obolibrary.org/obo/GO_0140459 NCBITaxon:42113 biolink:OrganismalEntity Clitellata go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_42113 GO:0140450 biolink:BiologicalProcess protein targeting to Golgi apparatus The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation). go-plus.json http://purl.obolibrary.org/obo/GO_0140450 CHEBI:35940 biolink:ChemicalSubstance protirelin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35940 chebi_ph7_3 CHEBI:35942 biolink:ChemicalSubstance neurotransmitter agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35942 GO:0140451 biolink:CellularComponent counting factor complex A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum. go-plus.json http://purl.obolibrary.org/obo/GO_0140451 CHEBI:35941 biolink:ChemicalSubstance serotonergic agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_35941 GO:0140454 biolink:BiologicalProcess protein aggregate center assembly The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. go-plus.json PAC assembly|protein aggregate center formation|protein aggregate centre assembly http://purl.obolibrary.org/obo/GO_0140454 CHEBI:11951 biolink:ChemicalSubstance 4-acetamidobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11951 chebi_ph7_3 CHEBI:60911 biolink:ChemicalSubstance racemate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60911 GO:0140453 biolink:CellularComponent protein aggregate center Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. go-plus.json PAC|protein aggregate centre http://purl.obolibrary.org/obo/GO_0140453 CHEBI:60913 biolink:ChemicalSubstance ganglioside GT1b go-plus.json http://purl.obolibrary.org/obo/CHEBI_60913 NCBITaxon:8511 biolink:OrganismalEntity Iguania go-plus.json Lacertilia|iguanian lizards http://purl.obolibrary.org/obo/NCBITaxon_8511 GO:0140489 biolink:MolecularActivity molecular template activity The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence. go-plus.json http://purl.obolibrary.org/obo/GO_0140489 GO:0140488 biolink:MolecularActivity heme receptor activity Binding specifically to heme to deliver it to a transport vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0140488 CHEBI:35915 biolink:ChemicalSubstance sterol ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_35915 chebi_ph7_3 CHEBI:11987 biolink:ChemicalSubstance 4-formylbenzenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11987 chebi_ph7_3 GO:0140481 biolink:MolecularActivity ABC-type iron-sulfur cluster transporter activity Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out). TC:3.A.1.210.1 go-plus.json ATPase-coupled Fe-S cluster transmembrane transporter activity|ATPase-coupled iron-sulfur cluster transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140481 GO:0140480 biolink:BiologicalProcess mitotic spindle pole body insertion into the nuclear envelope A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane. go-plus.json establishment of spindle pole body localization to nuclear envelope|establishment of spindle pole body localisation in nuclear envelope|establishment of spindle pole body localization in nuclear envelope http://purl.obolibrary.org/obo/GO_0140480 GO:0140483 biolink:MolecularActivity kinetochore adaptor activity The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way. go-plus.json inner kinetochore adaptor activity|outer kinetochore adaptor activity http://purl.obolibrary.org/obo/GO_0140483 GO:0140482 biolink:MolecularActivity iron sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of iron. go-plus.json http://purl.obolibrary.org/obo/GO_0140482 GO:0140485 biolink:MolecularActivity 5-aminolevulinic acid transmembrane transporter activity Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other. RHEA:64816 go-plus.json http://purl.obolibrary.org/obo/GO_0140485 CHEBI:11986 biolink:ChemicalSubstance 4-fluoro-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_11986 GO:0140484 biolink:BiologicalProcess 5-aminolevulinic acid import across plasma membrane The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140484 GO:0140487 biolink:MolecularActivity metal ion sequestering activity The selective interaction of a protein with a metal ion to prevent it from interacting with sensitive components of a biological system. go-plus.json http://purl.obolibrary.org/obo/GO_0140487 GO:0140486 biolink:MolecularActivity zinc ion sequestering activity The selective interaction of a protein with a zinc ion to prevent it from interacting with sensitive components of a biological system. go-plus.json http://purl.obolibrary.org/obo/GO_0140486 CHEBI:35910 biolink:ChemicalSubstance 2-oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35910 CHEBI:60924 biolink:ChemicalSubstance keratan sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60924 CHEBI:60926 biolink:ChemicalSubstance amino monosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60926 CHEBI:60929 biolink:ChemicalSubstance arbutin 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60929 chebi_ph7_3 CHEBI:35924 biolink:ChemicalSubstance peroxol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35924 chebi_ph7_3 CHEBI:35923 biolink:ChemicalSubstance hydroperoxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35923 GO:0140479 biolink:BiologicalProcess ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide. go-plus.json http://purl.obolibrary.org/obo/GO_0140479 GO:0140472 biolink:CellularComponent cell cortex of non-growing cell tip The region directly beneath the plasma membrane at the cell tip at which no growth takes place. go-plus.json http://purl.obolibrary.org/obo/GO_0140472 GO:0140471 biolink:BiologicalProcess positive regulation of transepithelial migration of symbiont in host Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host. go-plus.json positive regulation of transmigration of symbiont in host http://purl.obolibrary.org/obo/GO_0140471 GO:0140474 biolink:MolecularActivity mitochondrion-endoplasmic reticulum membrane tether activity The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion. go-plus.json endoplasmic reticulum-mitochondrion membrane adaptor activity|mitochondrion-endoplasmic reticulum membrane adaptor activity|ER-mitochondrion membrane adaptor activity|mitochondrion-ER membrane tether activity|mitochondrion-ER membrane adaptor activity|ER-mitochondrion membrane tether activity|endoplasmic reticulum-mitochondrion membrane tether activity http://purl.obolibrary.org/obo/GO_0140474 GO:0140473 biolink:MolecularActivity telomere-nuclear envelope anchor activity The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location. go-plus.json nuclear envelope-telomere anchor activity|telomere-nuclear envelope anchoring activity http://purl.obolibrary.org/obo/GO_0140473 CHEBI:60933 biolink:ChemicalSubstance (E)-4-(trimethylammonio)but-2-enoyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60933 chebi_ph7_3 GO:0140475 biolink:MolecularActivity spindle pole body anchor activity The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way. go-plus.json http://purl.obolibrary.org/obo/GO_0140475 CHEBI:60932 biolink:ChemicalSubstance (R)-carnitinyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60932 chebi_ph7_3 CHEBI:11972 biolink:ChemicalSubstance 4-carboxymethylenebut-2-en-4-olide go-plus.json http://purl.obolibrary.org/obo/CHEBI_11972 CHEBI:60935 biolink:ChemicalSubstance sinapate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_60935 chebi_ph7_3 CHEBI:60938 biolink:ChemicalSubstance glucuronoxylan go-plus.json http://purl.obolibrary.org/obo/CHEBI_60938 CHEBI:84904 biolink:ChemicalSubstance (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84904 chebi_ph7_3 GO:0140423 biolink:BiologicalProcess effector-mediated suppression of host pattern-triggered immunity signaling A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants. go-plus.json effector-mediated suppression of PTI signalling|effector-mediated suppression of host pattern recognition receptor signaling|effector-mediated suppression of host PRR signalling|effector-mediated suppression of pattern-triggered immunity signaling|effector-mediated suppression of host PRR signaling http://purl.obolibrary.org/obo/GO_0140423 GO:0140425 biolink:BiologicalProcess galactose import across plasma membrane The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140425 CHEBI:84900 biolink:ChemicalSubstance 12-deoxynogalonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84900 chebi_ph7_3 GO:0140426 biolink:BiologicalProcess PAMP-triggered immunity signalling pathway Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. go-plus.json PTI signalling|MAMP-triggered immunity signalling|pathogen-associated molecular pattern signalling http://purl.obolibrary.org/obo/GO_0140426 GO:0140429 biolink:BiologicalProcess positive regulation of mitotic sister chromatid biorientation Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. go-plus.json repair of mitotic merotelic kinetochore attachment defect|repair of mitotic merotelic kinetochore attachment defects|correction of syntelic kinetochore attachment, mitotic|correction of mono-orientation defects|repair of mitotic mono-orientation defect|repair of mitotic mono-orientation defects|correction of merotelic kinetochore attachment, mitotic http://purl.obolibrary.org/obo/GO_0140429 CHEBI:60940 biolink:ChemicalSubstance D-mannosyl-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60940 CHEBI:60941 biolink:ChemicalSubstance prenylcysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60941 GO:0140421 biolink:BiologicalProcess endocytic heme import into cell The directed movement into cell of externally available heme by receptor-mediated endocytosis. go-plus.json heme assimilation http://purl.obolibrary.org/obo/GO_0140421 GO:0140420 biolink:BiologicalProcess heme import into cell The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. go-plus.json heme assimilation http://purl.obolibrary.org/obo/GO_0140420 CHEBI:60943 biolink:ChemicalSubstance 5-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_60943 CHEBI:60948 biolink:ChemicalSubstance alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc go-plus.json http://purl.obolibrary.org/obo/CHEBI_60948 chebi_ph7_3 UBERON:0016398 biolink:AnatomicalEntity lymph node of lower limb A lymph node that is part of a hindlimb. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016398 GO:0140412 biolink:MolecularActivity zinc:bicarbonate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in). go-plus.json http://purl.obolibrary.org/obo/GO_0140412 CHEBI:35902 biolink:ChemicalSubstance oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35902 CHEBI:84913 biolink:ChemicalSubstance 3-amino-N-(trans-3-carbamoyloxirane-2-carbonyl)-L-alanine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84913 chebi_ph7_3 CHEBI:84912 biolink:ChemicalSubstance dapdiamide E zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84912 chebi_ph7_3 GO:0140414 biolink:MolecularActivity phosphopantetheine-dependent carrier activity Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate. go-plus.json carrier protein activity http://purl.obolibrary.org/obo/GO_0140414 CHEBI:35903 biolink:ChemicalSubstance oxo carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35903 GO:0140413 biolink:MolecularActivity zinc:bicarbonate:selenite symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out). go-plus.json http://purl.obolibrary.org/obo/GO_0140413 GO:0140416 biolink:MolecularActivity transcription regulator inhibitor activity A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification. go-plus.json DNA-binding transcription factor inhibitor activity http://purl.obolibrary.org/obo/GO_0140416 GO:0140415 biolink:BiologicalProcess effector-mediated modulation of host defenses by symbiont A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0140415 UBERON:0016399 biolink:AnatomicalEntity lymph node of upper limb A lymph node that is part of a forelimb. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016399 CHEBI:35908 biolink:ChemicalSubstance glutaramate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35908 chebi_ph7_3 GO:0140418 biolink:BiologicalProcess effector-mediated modulation of host process by symbiont A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json effector mediated modulation of host process by symbiont|effector-dependent modulation of host process by symbiont|effector triggered modulation of host process by symbiont http://purl.obolibrary.org/obo/GO_0140418 GO:0140417 biolink:MolecularActivity ATP-sensitive calcium-release channel activity Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0140417 CHEBI:35907 biolink:ChemicalSubstance glutarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35907 CHEBI:60951 biolink:ChemicalSubstance flavonoid phytoalexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60951 CHEBI:60952 biolink:ChemicalSubstance diterpene phytoalexin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60952 CHEBI:60955 biolink:ChemicalSubstance 9(S)-HPODE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60955 chebi_ph7_3 CHEBI:35900 biolink:ChemicalSubstance but-3-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35900 chebi_ph7_3 GO:0140410 biolink:MolecularActivity solute:bicarbonate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + HCO3-(out) = solute(in) + HCO3-(in). go-plus.json http://purl.obolibrary.org/obo/GO_0140410 CHEBI:60954 biolink:ChemicalSubstance 2-hydroxy-2-methylbutanenitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_60954 chebi_ph7_3 CHEBI:60957 biolink:ChemicalSubstance colneleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60957 chebi_ph7_3 CHEBI:60956 biolink:ChemicalSubstance colneleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60956 CHEBI:60959 biolink:ChemicalSubstance colnelenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60959 CHEBI:84925 biolink:ChemicalSubstance omega-hydroxyphytanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84925 CHEBI:11946 biolink:ChemicalSubstance 4-(trimethylammonio)but-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11946 chebi_ph7_3 GO:0140445 biolink:CellularComponent chromosome, telomeric repeat region A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop. go-plus.json http://purl.obolibrary.org/obo/GO_0140445 GO:0140444 biolink:MolecularActivity cytoskeleton-nuclear membrane anchor activity The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane. go-plus.json nuclear membrane-cytoskeleton anchor activity|cytoskeleton nuclear membrane anchor activity|cytoskeletal protein-nuclear membrane anchor activity|cytoskeletal protein-nuclear membrane adaptor activity http://purl.obolibrary.org/obo/GO_0140444 GO:0140447 biolink:BiologicalProcess cytokine precursor processing The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine. go-plus.json interleukin maturation|interleukin processing http://purl.obolibrary.org/obo/GO_0140447 CHEBI:11944 biolink:ChemicalSubstance 4-(hydroxymethyl)benzenesulfonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11944 chebi_ph7_3 GO:0140446 biolink:BiologicalProcess fumigermin biosynthetic process The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus. go-plus.json fumigermin synthesis|fumigermin formation|fumigermin biosynthesis|fumigermin anabolism http://purl.obolibrary.org/obo/GO_0140446 CHEBI:84921 biolink:ChemicalSubstance 7-hydroxylaurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84921 chebi_ph7_3 GO:0140449 biolink:MolecularActivity centromere-nuclear envelope anchor activity The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location. go-plus.json centromere nuclear envelope tether activity|centromere nuclear envelope anchor activity|nuclear envelope-centromere tether activity|centromere-inner nuclear envelope tether activity|nuclear envelope-centromere anchor activity|centromere-inner nuclear envelope anchor activity|chromosome, centromeric region-nuclear envelope anchor activity http://purl.obolibrary.org/obo/GO_0140449 GO:0140448 biolink:BiologicalProcess signaling receptor ligand precursor processing The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand. go-plus.json signal maturation|ligand maturation http://purl.obolibrary.org/obo/GO_0140448 CHEBI:60960 biolink:ChemicalSubstance colnelenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60960 chebi_ph7_3 CHEBI:60962 biolink:ChemicalSubstance (9S,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60962 chebi_ph7_3 CHEBI:60961 biolink:ChemicalSubstance (9S,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60961 GO:0140441 biolink:MolecularActivity protein-cysteine S-arachidonoyltransferase activity Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein]. RHEA:59748 go-plus.json http://purl.obolibrary.org/obo/GO_0140441 GO:0140440 biolink:MolecularActivity protein-cysteine S-oleoyltransferase activity Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein]. RHEA:59744 go-plus.json http://purl.obolibrary.org/obo/GO_0140440 CHEBI:60963 biolink:ChemicalSubstance colanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60963 GO:0140443 biolink:MolecularActivity mitochondrion-plasma membrane adaptor activity The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion. go-plus.json mitochondrion plasma membrane adaptor activity|mitochondrion plasma membrane tether activity|plasma membrane-mitochondrion adaptor activity|plasma membrane-mitochondrion tether activity http://purl.obolibrary.org/obo/GO_0140443 GO:0140442 biolink:MolecularActivity peroxide sensor activity Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0140442 CHEBI:60968 biolink:ChemicalSubstance presilphiperfolan-8beta-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_60968 chebi_ph7_3 CHEBI:84939 biolink:ChemicalSubstance omega-hydroxy-15-methylpalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84939 NCBITaxon:284591 biolink:OrganismalEntity Yarrowia lipolytica CLIB122 go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_284591 CHEBI:84936 biolink:ChemicalSubstance ethyl octadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84936 chebi_ph7_3 GO:0140434 biolink:BiologicalProcess positive regulation of protein localization to meiotic spindle pole body Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0140434 CHEBI:11935 biolink:ChemicalSubstance 4-(beta-D-glucosyloxy)benzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11935 chebi_ph7_3 GO:0140433 biolink:BiologicalProcess regulation of protein localization to meiotic spindle pole body Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0140433 CHEBI:84934 biolink:ChemicalSubstance ethyl palmitoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84934 chebi_ph7_3 CHEBI:84933 biolink:ChemicalSubstance N-acetyl-D-muramoyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84933 GO:0140435 biolink:BiologicalProcess negative regulation of protein localization to meiotic spindle pole body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body. go-plus.json http://purl.obolibrary.org/obo/GO_0140435 CHEBI:84932 biolink:ChemicalSubstance ethyl hexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84932 chebi_ph7_3 GO:0140438 biolink:BiologicalProcess protein stearoylation The covalent attachment of a stearoyl group to an amino acid in a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140438 GO:0140439 biolink:MolecularActivity protein-cysteine S-stearoyltransferase activity Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein]. RHEA:59740 go-plus.json http://purl.obolibrary.org/obo/GO_0140439 CHEBI:60971 biolink:ChemicalSubstance aminophospholipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60971 CHEBI:60973 biolink:ChemicalSubstance suberin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60973 GO:0140430 biolink:BiologicalProcess positive regulation of chromosome passenger complex localization to kinetochore Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore. go-plus.json http://purl.obolibrary.org/obo/GO_0140430 CHEBI:60974 biolink:ChemicalSubstance cyanoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60974 GO:0140432 biolink:MolecularActivity 5'-hydroxyl dinucleotide hydrolase Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140432 CHEBI:60977 biolink:ChemicalSubstance phenylalkylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60977 GO:0140431 biolink:MolecularActivity DNA-(abasic site) binding Binding to a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base. go-plus.json DNA-(apurinic site) binding|DNA-(apyrimidinic site) binding|DNA AP site binding|DNA-(apurinic site/apyrimidinic site) binding http://purl.obolibrary.org/obo/GO_0140431 CHEBI:60979 biolink:ChemicalSubstance alpha-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_60979 CHEBI:60978 biolink:ChemicalSubstance ketogluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60978 GO:0042082 biolink:BiologicalProcess GSI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage. go-plus.json GSI anchor formation|GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process|GSI anchor biosynthesis|GSI anchor anabolism|GSI anchor synthesis http://purl.obolibrary.org/obo/GO_0042082 GO:0032717 biolink:BiologicalProcess negative regulation of interleukin-8 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. go-plus.json negative regulation of interleukin-8 biosynthetic process|downregulation of interleukin-8 production|down regulation of interleukin-8 production|negative regulation of IL-8 production|inhibition of interleukin-8 production|down-regulation of interleukin-8 production|negative regulation of interleukin-8 secretion http://purl.obolibrary.org/obo/GO_0032717 CHEBI:21374 biolink:ChemicalSubstance L-prolinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_21374 GO:0042081 biolink:BiologicalProcess GSI anchor metabolic process The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane. go-plus.json GPI/GSI anchor metabolic process|GPI/GSI anchor metabolism|GSI anchor metabolism http://purl.obolibrary.org/obo/GO_0042081 GO:0032716 biolink:BiologicalProcess negative regulation of interleukin-7 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production. go-plus.json negative regulation of interleukin-7 biosynthetic process|downregulation of interleukin-7 production|down regulation of interleukin-7 production|inhibition of interleukin-7 production|negative regulation of IL-7 production|down-regulation of interleukin-7 production|negative regulation of interleukin-7 secretion http://purl.obolibrary.org/obo/GO_0032716 GO:0032715 biolink:BiologicalProcess negative regulation of interleukin-6 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. go-plus.json negative regulation of interleukin-6 secretion|negative regulation of interleukin-6 biosynthetic process|downregulation of interleukin-6 production|down regulation of interleukin-6 production|negative regulation of IL-6 production|inhibition of interleukin-6 production|down-regulation of interleukin-6 production http://purl.obolibrary.org/obo/GO_0032715 GO:0042084 biolink:MolecularActivity 5-methyltetrahydrofolate-dependent methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate. go-plus.json http://purl.obolibrary.org/obo/GO_0042084 CHEBI:21376 biolink:ChemicalSubstance rhamnonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21376 GO:0032714 biolink:BiologicalProcess negative regulation of interleukin-5 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production. go-plus.json negative regulation of interleukin-5 biosynthetic process|negative regulation of interleukin-5 secretion|downregulation of interleukin-5 production|down regulation of interleukin-5 production|inhibition of interleukin-5 production|negative regulation of IL-5 production|down-regulation of interleukin-5 production http://purl.obolibrary.org/obo/GO_0032714 GO:0042083 biolink:MolecularActivity 5,10-methylenetetrahydrofolate-dependent methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate. go-plus.json http://purl.obolibrary.org/obo/GO_0042083 GO:0032713 biolink:BiologicalProcess negative regulation of interleukin-4 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production. go-plus.json downregulation of interleukin-4 production|negative regulation of interleukin-4 secretion|down regulation of interleukin-4 production|negative regulation of IL-4 production|inhibition of interleukin-4 production|down-regulation of interleukin-4 production|negative regulation of interleukin-4 biosynthetic process http://purl.obolibrary.org/obo/GO_0032713 GO:0032712 biolink:BiologicalProcess negative regulation of interleukin-3 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production. go-plus.json down regulation of interleukin-3 production|inhibition of interleukin-3 production|negative regulation of IL-3 production|down-regulation of interleukin-3 production|negative regulation of interleukin-3 biosynthetic process|downregulation of interleukin-3 production http://purl.obolibrary.org/obo/GO_0032712 GO:0032711 biolink:BiologicalProcess negative regulation of interleukin-27 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production. go-plus.json inhibition of interleukin-27 production|negative regulation of interleukin-27 biosynthetic process|negative regulation of IL-27 production|down regulation of interleukin-27 production|downregulation of interleukin-27 production|down-regulation of interleukin-27 production http://purl.obolibrary.org/obo/GO_0032711 GO:0042080 biolink:BiologicalProcess obsolete GPI/GSI anchor biosynthetic process OBSOLETE. (Was not defined before being made obsolete). go-plus.json GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process|GPI/GSI anchor anabolism|GPI/GSI anchor synthesis|GPI/GSI anchor formation http://purl.obolibrary.org/obo/GO_0042080 GO:0032710 biolink:BiologicalProcess negative regulation of interleukin-26 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production. go-plus.json inhibition of interleukin-26 production|negative regulation of interleukin-26 biosynthetic process|negative regulation of IL-26 production|down regulation of interleukin-26 production|downregulation of interleukin-26 production|down-regulation of interleukin-26 production http://purl.obolibrary.org/obo/GO_0032710 GO:0042089 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042089 GO:0042086 biolink:MolecularActivity 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin. go-plus.json http://purl.obolibrary.org/obo/GO_0042086 GO:0042085 biolink:MolecularActivity 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0042085 GO:0032719 biolink:BiologicalProcess negative regulation of TRAIL production Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production. go-plus.json down-regulation of TRAIL production|negative regulation of TRAIL biosynthetic process|downregulation of TRAIL production|down regulation of TRAIL production|inhibition of TRAIL production http://purl.obolibrary.org/obo/GO_0032719 GO:0042088 biolink:BiologicalProcess T-helper 1 type immune response An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. go-plus.json Th1 immune response http://purl.obolibrary.org/obo/GO_0042088 GO:0032718 biolink:BiologicalProcess negative regulation of interleukin-9 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production. go-plus.json negative regulation of interleukin-9 biosynthetic process|downregulation of interleukin-9 production|down regulation of interleukin-9 production|inhibition of interleukin-9 production|negative regulation of IL-9 production|down-regulation of interleukin-9 production http://purl.obolibrary.org/obo/GO_0032718 GO:0042087 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042087 UBERON:0006960 biolink:AnatomicalEntity ovary stroma The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. go-plus.json ovary stroma|stroma ovarica|stroma ovarii|interstitial tissue of ovary|stroma of the ovary|ovarian stroma http://purl.obolibrary.org/obo/UBERON_0006960 CHEBI:3306 biolink:ChemicalSubstance calcitonin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3306 UBERON:0006966 biolink:AnatomicalEntity coronary capillary A capillary that is part of the coronary system. go-plus.json heart capillary http://purl.obolibrary.org/obo/UBERON_0006966 CHEBI:59988 biolink:ChemicalSubstance alpha-tyvelopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_59988 chebi_ph7_3 UBERON:0006965 biolink:AnatomicalEntity vascular cord The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006965 CHEBI:59985 biolink:ChemicalSubstance beta-D-glucosyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59985 chebi_ph7_3 GO:0032706 biolink:BiologicalProcess negative regulation of interleukin-22 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production. go-plus.json downregulation of interleukin-22 production|down-regulation of interleukin-22 production|inhibition of interleukin-22 production|negative regulation of interleukin-22 biosynthetic process|negative regulation of IL-22 production|down regulation of interleukin-22 production http://purl.obolibrary.org/obo/GO_0032706 GO:0042093 biolink:BiologicalProcess T-helper cell differentiation The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. go-plus.json helper T cell differentiation|T-helper cell development http://purl.obolibrary.org/obo/GO_0042093 GO:0032705 biolink:BiologicalProcess negative regulation of interleukin-21 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production. go-plus.json downregulation of interleukin-21 production|down-regulation of interleukin-21 production|negative regulation of interleukin-21 biosynthetic process|down regulation of interleukin-21 production http://purl.obolibrary.org/obo/GO_0032705 GO:0042092 biolink:BiologicalProcess type 2 immune response An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. go-plus.json T-helper 2 type immune response|Th2 immune response http://purl.obolibrary.org/obo/GO_0042092 GO:0032704 biolink:BiologicalProcess negative regulation of interleukin-20 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production. go-plus.json downregulation of interleukin-20 production|down-regulation of interleukin-20 production|inhibition of interleukin-20 production|negative regulation of interleukin-20 biosynthetic process|negative regulation of IL-20 production|down regulation of interleukin-20 production http://purl.obolibrary.org/obo/GO_0032704 GO:0042095 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042095 GO:0032703 biolink:BiologicalProcess negative regulation of interleukin-2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production. go-plus.json down-regulation of interleukin-2 production|negative regulation of interleukin-2 biosynthetic process|downregulation of interleukin-2 production|down regulation of interleukin-2 production|negative regulation of interleukin-2 secretion|negative regulation of IL-2 production|inhibition of interleukin-2 production http://purl.obolibrary.org/obo/GO_0032703 GO:0042094 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042094 GO:0032702 biolink:BiologicalProcess negative regulation of interleukin-19 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production. go-plus.json negative regulation of IL-19 production|down regulation of interleukin-19 production|downregulation of interleukin-19 production|down-regulation of interleukin-19 production|inhibition of interleukin-19 production|negative regulation of interleukin-19 biosynthetic process http://purl.obolibrary.org/obo/GO_0032702 GO:0032701 biolink:BiologicalProcess negative regulation of interleukin-18 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production. go-plus.json negative regulation of IL-18 production|down regulation of interleukin-18 production|downregulation of interleukin-18 production|negative regulation of interleukin-18 secretion|down-regulation of interleukin-18 production|inhibition of interleukin-18 production|negative regulation of interleukin-18 biosynthetic process http://purl.obolibrary.org/obo/GO_0032701 GO:0032700 biolink:BiologicalProcess negative regulation of interleukin-17 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. go-plus.json negative regulation of IL-17 production|down regulation of interleukin-17 production|negative regulation of CTLA-8 production|downregulation of interleukin-17 production|negative regulation of interleukin-17 secretion|negative regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion|inhibition of interleukin-17 production|negative regulation of interleukin-17 biosynthetic process http://purl.obolibrary.org/obo/GO_0032700 GO:0042091 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042091 UBERON:0006948 biolink:AnatomicalEntity efferent duct epithelium An epithelium that is part of a efferent duct. go-plus.json epithelium of efferent ductule of testis http://purl.obolibrary.org/obo/UBERON_0006948 UBERON:0006947 biolink:AnatomicalEntity male genital duct A duct or series of ducts that transports sperm from the gonad. In mammals this is from the seminiferous tubules through rete testis, vas efferentia, epididymis, vas deferens, ejeculatory duct to the urethra. go-plus.json sperm ducts|sperm duct http://purl.obolibrary.org/obo/UBERON_0006947 GO:0042090 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042090 GO:0042097 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042097 GO:0042096 biolink:MolecularActivity obsolete alpha-beta T cell receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json alpha-beta T cell receptor activity http://purl.obolibrary.org/obo/GO_0042096 GO:0032709 biolink:BiologicalProcess negative regulation of interleukin-25 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production. go-plus.json negative regulation of IL-25 production|down regulation of interleukin-25 production|downregulation of interleukin-25 production|negative regulation of interleukin-25 secretion|down-regulation of interleukin-25 production|inhibition of interleukin-25 production|negative regulation of interleukin-25 biosynthetic process http://purl.obolibrary.org/obo/GO_0032709 GO:0032708 biolink:BiologicalProcess negative regulation of interleukin-24 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production. go-plus.json negative regulation of IL-24 production|down regulation of interleukin-24 production|downregulation of interleukin-24 production|down-regulation of interleukin-24 production|inhibition of interleukin-24 production|negative regulation of interleukin-24 biosynthetic process http://purl.obolibrary.org/obo/GO_0032708 GO:0042099 biolink:MolecularActivity obsolete gamma-delta T cell receptor activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json gamma-delta T cell receptor activity http://purl.obolibrary.org/obo/GO_0042099 GO:0032707 biolink:BiologicalProcess negative regulation of interleukin-23 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production. go-plus.json down regulation of interleukin-23 production|downregulation of interleukin-23 production|down-regulation of interleukin-23 production|inhibition of interleukin-23 production|negative regulation of interleukin-23 biosynthetic process|negative regulation of IL-23 production http://purl.obolibrary.org/obo/GO_0032707 GO:0042098 biolink:BiologicalProcess T cell proliferation The expansion of a T cell population by cell division. Follows T cell activation. go-plus.json T lymphocyte proliferation|T-cell proliferation|T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0042098 CHEBI:59971 biolink:ChemicalSubstance GDP-D-glycero-alpha-D-manno-heptose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59971 chebi_ph7_3 UBERON:0006957 biolink:AnatomicalEntity submandibular gland primordium epithelium An epithelium that is part of a submandibular gland primordium. go-plus.json submaxillary gland primordium epithelium http://purl.obolibrary.org/obo/UBERON_0006957 CHEBI:59979 biolink:ChemicalSubstance 3',5'-di-O-methyltricetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59979 UBERON:0006955 biolink:AnatomicalEntity uterine epithelium An epithelium that is part of a uterus. go-plus.json uterus epithelium http://purl.obolibrary.org/obo/UBERON_0006955 NCBITaxon:2640012 biolink:OrganismalEntity unclassified Synechocystis go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2640012 CHEBI:59976 biolink:ChemicalSubstance 3'-O-methyltricetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59976 UBERON:0006953 biolink:AnatomicalEntity ejaculatory duct epithelium The ejaculatory duct epithelium is composed of cuboidal to columnar cells between or through which project the terminal parts of the ducts of the unicellular prostate glands. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006953 UBERON:0006938 biolink:AnatomicalEntity pinna surface epithelium An epithelium that is part of a pinna. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006938 UBERON:0006937 biolink:AnatomicalEntity inner ear epithelium the epithelial cell layer containing the sensory hair cells and their associated sensory nerve terminals go-plus.json http://purl.obolibrary.org/obo/UBERON_0006937 UBERON:0006936 biolink:AnatomicalEntity thymus subcapsular epithelium the epithelial cells lining the capsule and trabeculae of the thymus go-plus.json http://purl.obolibrary.org/obo/UBERON_0006936 CHEBI:59969 biolink:ChemicalSubstance GDP-D-glycero-alpha-D-manno-heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_59969 CHEBI:35992 biolink:ChemicalSubstance penams go-plus.json http://purl.obolibrary.org/obo/CHEBI_35992 CHEBI:35998 biolink:ChemicalSubstance tridecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35998 chebi_ph7_3 UBERON:0006946 biolink:AnatomicalEntity efferent duct The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis. go-plus.json seminal duct|vasa efferentia|efferent ductule|ductuli efferentes testis http://purl.obolibrary.org/obo/UBERON_0006946 CHEBI:59967 biolink:ChemicalSubstance ADP-D-glycero-beta-D-manno-heptose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59967 chebi_ph7_3 CHEBI:59966 biolink:ChemicalSubstance ADP-D-glycero-beta-D-manno-heptose go-plus.json http://purl.obolibrary.org/obo/CHEBI_59966 CHEBI:59964 biolink:ChemicalSubstance imidazolium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59964 CHEBI:35990 biolink:ChemicalSubstance bridged compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35990 CHEBI:59961 biolink:ChemicalSubstance alpha-selinene go-plus.json http://purl.obolibrary.org/obo/CHEBI_59961 chebi_ph7_3 CHEBI:21363 biolink:ChemicalSubstance L-methionine sulfone go-plus.json http://purl.obolibrary.org/obo/CHEBI_21363 UBERON:0006929 biolink:AnatomicalEntity glandular columnar epithelium Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0006929 CHEBI:59959 biolink:ChemicalSubstance (3R,6E)-nerolidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_59959 chebi_ph7_3 CHEBI:21368 biolink:ChemicalSubstance L-ornithine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_21368 CHEBI:59958 biolink:ChemicalSubstance (3S,6E)-nerolidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_59958 chebi_ph7_3 UBERON:0006925 biolink:AnatomicalEntity digestive system gland Any gland that is part of the digestive system. go-plus.json digestive gland http://purl.obolibrary.org/obo/UBERON_0006925 CHEBI:59957 biolink:ChemicalSubstance D-glycero-D-manno-heptose 1,7-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59957 chebi_ph7_3 UBERON:0006934 biolink:AnatomicalEntity sensory epithelium Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. go-plus.json neuroepithelium http://purl.obolibrary.org/obo/UBERON_0006934 CHEBI:59955 biolink:ChemicalSubstance D-glycero-D-manno-heptose 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59955 chebi_ph7_3 UBERON:0006932 biolink:AnatomicalEntity vestibular epithelium An epithelium that is part of a vestibular labyrinth. go-plus.json inner ear vestibular component epithelium|epithelium of vestibular labyrinth|vestibular sensory epithelium http://purl.obolibrary.org/obo/UBERON_0006932 CHEBI:59953 biolink:ChemicalSubstance thebaine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59953 chebi_ph7_3 UBERON:0006931 biolink:AnatomicalEntity stomach glandular region mucosa stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region. go-plus.json stomach glandular region glandular mucous membrane http://purl.obolibrary.org/obo/UBERON_0006931 UBERON:0006930 biolink:AnatomicalEntity glandular cuboidal epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0006930 CHEBI:59950 biolink:ChemicalSubstance neopinone(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59950 chebi_ph7_3 CHEBI:21332 biolink:ChemicalSubstance L-idarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_21332 chebi_ph7_3 CHEBI:21333 biolink:ChemicalSubstance L-idaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21333 CHEBI:21336 biolink:ChemicalSubstance L-idonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21336 CHEBI:59948 biolink:ChemicalSubstance columbianetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59948 chebi_ph7_3 CHEBI:59947 biolink:ChemicalSubstance (S)-2-ureidoglycine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59947 chebi_ph7_3 CHEBI:35979 biolink:ChemicalSubstance dioxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35979 CHEBI:35971 biolink:ChemicalSubstance 6-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35971 CHEBI:35970 biolink:ChemicalSubstance 4-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35970 CHEBI:35973 biolink:ChemicalSubstance 3-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35973 chebi_ph7_3 CHEBI:3347 biolink:ChemicalSubstance candesartan go-plus.json http://purl.obolibrary.org/obo/CHEBI_3347 CHEBI:35972 biolink:ChemicalSubstance dihydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35972 CHEBI:3349 biolink:ChemicalSubstance candicidin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_3349 CHEBI:35975 biolink:ChemicalSubstance 5-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35975 CHEBI:35974 biolink:ChemicalSubstance 4-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35974 CHEBI:35976 biolink:ChemicalSubstance 6-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35976 CHEBI:21337 biolink:ChemicalSubstance idonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21337 CHEBI:59945 biolink:ChemicalSubstance (S)-2-ureidoglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_59945 GO:0140499 biolink:BiologicalProcess negative regulation of mitotic spindle assembly checkpoint signaling Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0140499 GO:0140492 biolink:MolecularActivity metal-dependent deubiquitinase activity Catalysis of the metal-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin. go-plus.json metal-dependent ubiquitin-like hydrolase activity|metal-dependent ubiquitinyl-like hydrolase activity http://purl.obolibrary.org/obo/GO_0140492 GO:0140491 biolink:MolecularActivity ubiquitin-like hydrolase activity An activity that cleaves ubiquitin or ubiquitin-like proteins (ULP) from target proteins. go-plus.json ubiquitinyl-like hydrolase activity http://purl.obolibrary.org/obo/GO_0140491 GO:0140494 biolink:CellularComponent migrasome A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0140494 CHEBI:35984 biolink:ChemicalSubstance 7-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35984 GO:0140493 biolink:BiologicalProcess very long-chain fatty acid beta-oxidation A fatty acid beta-oxidation pathway acting on fatty acid which has a chain length greater than C22 in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). go-plus.json http://purl.obolibrary.org/obo/GO_0140493 CHEBI:35983 biolink:ChemicalSubstance 7-oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35983 CHEBI:35986 biolink:ChemicalSubstance nonan-1-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35986 chebi_ph7_3 GO:0140496 biolink:MolecularActivity gamma-tubulin complex binding Binding to a gamma-tubulin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140496 GO:0140495 biolink:BiologicalProcess migracytosis A cell migration-dependent mechanism for releasing cellular contents. go-plus.json http://purl.obolibrary.org/obo/GO_0140495 CHEBI:3359 biolink:ChemicalSubstance cannabidiolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_3359 GO:0140498 biolink:CellularComponent mannan polymerase I complex A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the priming and elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p and Van1p. go-plus.json http://purl.obolibrary.org/obo/GO_0140498 GO:0140497 biolink:CellularComponent mannan polymerase II complex A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p. go-plus.json http://purl.obolibrary.org/obo/GO_0140497 CHEBI:35987 biolink:ChemicalSubstance diamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35987 CHEBI:59930 biolink:ChemicalSubstance N-formylmaleamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59930 GO:0140490 biolink:MolecularActivity microtubule nucleator activity The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly. go-plus.json microtubule nucleation template activity http://purl.obolibrary.org/obo/GO_0140490 CHEBI:21314 biolink:ChemicalSubstance glutamyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21314 CHEBI:35958 biolink:ChemicalSubstance epsilon-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35958 NCBITaxon:1728959 biolink:OrganismalEntity Aurantioideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1728959 CHEBI:35951 biolink:ChemicalSubstance dioxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35951 CHEBI:35950 biolink:ChemicalSubstance 4-oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35950 CHEBI:35952 biolink:ChemicalSubstance 5-oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35952 CHEBI:59924 biolink:ChemicalSubstance 5,6,7,8-tetrahydrosarcinapterin(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59924 chebi_ph7_3 CHEBI:59923 biolink:ChemicalSubstance coenzyme alpha-F420-3(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59923 chebi_ph7_3 CHEBI:59922 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_59922 CHEBI:59920 biolink:ChemicalSubstance coenzyme F420-1(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59920 chebi_ph7_3 UBERON:0006984 biolink:AnatomicalEntity anatomical surface A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n go-plus.json http://purl.obolibrary.org/obo/UBERON_0006984 CHEBI:59918 biolink:ChemicalSubstance acyl monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59918 chebi_ph7_3 CHEBI:59917 biolink:ChemicalSubstance 4-O-phosphohygromycin B(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59917 chebi_ph7_3 CHEBI:59916 biolink:ChemicalSubstance methylmalonyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59916 chebi_ph7_3 CHEBI:59914 biolink:ChemicalSubstance thio fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59914 CHEBI:35969 biolink:ChemicalSubstance 3-hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35969 CHEBI:35960 biolink:ChemicalSubstance 6-oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35960 CHEBI:35962 biolink:ChemicalSubstance sorbic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35962 CHEBI:35964 biolink:ChemicalSubstance penta-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35964 CHEBI:59913 biolink:ChemicalSubstance thio-fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59913 CHEBI:59911 biolink:ChemicalSubstance N-formylmaleamate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59911 chebi_ph7_3 CHEBI:59910 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosaminium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59910 chebi_ph7_3 OBA:0000099 biolink:OntologyClass membrane potential The electric potential of a membrane. go-plus.json electric potential of membrane http://purl.obolibrary.org/obo/OBA_0000099 OBA:0000098 biolink:OntologyClass membrane lipid distribution The spatial pattern of a lipid when measured in membrane. go-plus.json membrane lipid spatial pattern http://purl.obolibrary.org/obo/OBA_0000098 OBA:0000093 biolink:OntologyClass mRNA stability The macromolecular stability of a mRNA. go-plus.json macromolecular stability of mRNA http://purl.obolibrary.org/obo/OBA_0000093 OBA:0000092 biolink:OntologyClass lysosomal membrane permeability The permeability of a lysosomal membrane. go-plus.json permeability of lysosomal membrane http://purl.obolibrary.org/obo/OBA_0000092 GO:0042244 biolink:BiologicalProcess spore wall assembly The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore. go-plus.json spore wall formation|spore coat biosynthetic process|spore coat biosynthesis http://purl.obolibrary.org/obo/GO_0042244 GO:0042243 biolink:BiologicalProcess asexual spore wall assembly The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species. go-plus.json asexual spore wall formation http://purl.obolibrary.org/obo/GO_0042243 GO:0042246 biolink:BiologicalProcess tissue regeneration The regrowth of lost or destroyed tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0042246 OBA:0000091 biolink:OntologyClass lysosomal lumen pH The acidity when measured in lysosomal lumen. go-plus.json http://purl.obolibrary.org/obo/OBA_0000091 OBA:0000090 biolink:OntologyClass lung blood pressure The pressure of a blood when measured in lung. go-plus.json lung blood pressure http://purl.obolibrary.org/obo/OBA_0000090 GO:0042245 biolink:BiologicalProcess RNA repair Any process that results in the repair of damaged RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0042245 GO:0042240 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042240 GO:0042242 biolink:MolecularActivity cobyrinic acid a,c-diamide synthase activity Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide. EC:6.3.5.11|RHEA:26289 go-plus.json cobyrinate a,c-diamide synthase activity|cobyrinate a c diamide synthase activity|CobB|cobyrinate a,c diamide synthase activity|cobyrinate a c-diamide synthase activity http://purl.obolibrary.org/obo/GO_0042242 GO:0042241 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042241 GO:0042248 biolink:BiologicalProcess maintenance of polarity of follicular epithelium The maintenance of an established polarized follicular epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0042248 GO:0042247 biolink:BiologicalProcess establishment of planar polarity of follicular epithelium Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates. go-plus.json http://purl.obolibrary.org/obo/GO_0042247 GO:0042249 biolink:BiologicalProcess establishment of planar polarity of embryonic epithelium Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates. go-plus.json http://purl.obolibrary.org/obo/GO_0042249 PATO:0000001 biolink:OntologyClass quality A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities go-plus.json http://purl.obolibrary.org/obo/PATO_0000001 OBA:0000088 biolink:OntologyClass liquid surface tension The surface tension of a liquid configuration. go-plus.json surface tension of liquid configuration http://purl.obolibrary.org/obo/OBA_0000088 OBA:0000084 biolink:OntologyClass imaginal disc-derived wing size The size of a imaginal disc-derived wing. go-plus.json size of imaginal disc-derived wing http://purl.obolibrary.org/obo/OBA_0000084 GO:0042255 biolink:BiologicalProcess ribosome assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. go-plus.json ribosomal subunit assembly http://purl.obolibrary.org/obo/GO_0042255 goslim_yeast GO:0042254 biolink:BiologicalProcess ribosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. go-plus.json ribosome biogenesis and assembly http://purl.obolibrary.org/obo/GO_0042254 goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl|goslim_candida GO:0042257 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042257 GO:0042256 biolink:BiologicalProcess mature ribosome assembly The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0042256 GO:0042251 biolink:BiologicalProcess maintenance of polarity of larval imaginal disc epithelium The maintenance of an established polarized larval imaginal disc epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0042251 GO:0042250 biolink:BiologicalProcess maintenance of polarity of embryonic epithelium The maintenance of an established polarized embryonic epithelial sheet. go-plus.json http://purl.obolibrary.org/obo/GO_0042250 GO:0042253 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042253 GO:0042252 biolink:BiologicalProcess establishment of planar polarity of larval imaginal disc epithelium Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates. go-plus.json http://purl.obolibrary.org/obo/GO_0042252 GO:0042259 biolink:BiologicalProcess peptidyl-L-beta-methylthioasparagine biosynthetic process from peptidyl-asparagine The modification of peptidyl-asparagine to form peptidyl-L-beta-methylthioasparagine, typical of bacterial ribosomal protein S12. RESID:AA0320 go-plus.json peptidyl-L-beta-methylthioasparagine anabolism from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine formation from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine synthesis from peptidyl-asparagine http://purl.obolibrary.org/obo/GO_0042259 GO:0042258 biolink:BiologicalProcess molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide. RESID:AA0319 go-plus.json http://purl.obolibrary.org/obo/GO_0042258 OBA:0000089 biolink:OntologyClass long-term neuronal synaptic plasticity go-plus.json http://purl.obolibrary.org/obo/OBA_0000089 OBA:0000074 biolink:OntologyClass heart contraction rate The rate of a heart contraction. go-plus.json rate of heart contraction http://purl.obolibrary.org/obo/OBA_0000074 GO:0042260 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042260 GO:0032899 biolink:BiologicalProcess regulation of neurotrophin production Any process that modulates the frequency, rate, or extent of production of a neurotrophin. go-plus.json http://purl.obolibrary.org/obo/GO_0032899 GO:0032898 biolink:BiologicalProcess neurotrophin production The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth. go-plus.json http://purl.obolibrary.org/obo/GO_0032898 GO:0032897 biolink:BiologicalProcess negative regulation of viral transcription Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription. go-plus.json down-regulation of viral transcription|inhibition of viral transcription|down regulation of viral transcription|downregulation of viral transcription http://purl.obolibrary.org/obo/GO_0032897 OBA:0000072 biolink:OntologyClass follicle cell microvillus length The microvillus length of a follicle cell. go-plus.json microvillus length of follicle cell http://purl.obolibrary.org/obo/OBA_0000072 GO:0042266 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042266 GO:0042265 biolink:BiologicalProcess peptidyl-asparagine hydroxylation The hydroxylation of peptidyl-asparagine to form peptidyl-hydroxyasparagine. go-plus.json peptidyl-aspartic acid/asparagine hydroxylation http://purl.obolibrary.org/obo/GO_0042265 GO:0042268 biolink:BiologicalProcess regulation of cytolysis Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0042268 GO:0042267 biolink:BiologicalProcess natural killer cell mediated cytotoxicity The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. go-plus.json natural killer cell mediated cell killing|NK cell mediated cell death|natural killer cell mediated cytolysis|natural killer cell mediated cell death|NK cell mediated cytolysis|killer activity|NK cell mediated cytotoxicity|natural killer-cell mediated cytolysis|NK cell mediated cell killing http://purl.obolibrary.org/obo/GO_0042267 GO:0042262 biolink:BiologicalProcess DNA protection Any process in which DNA is protected from damage by, for example, oxidative stress. go-plus.json http://purl.obolibrary.org/obo/GO_0042262 GO:0042261 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042261 GO:0042264 biolink:BiologicalProcess peptidyl-aspartic acid hydroxylation The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid. go-plus.json peptidyl-aspartic acid/asparagine hydroxylation http://purl.obolibrary.org/obo/GO_0042264 GO:0042263 biolink:MolecularActivity neuropeptide F receptor activity Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa. go-plus.json NPF receptor activity http://purl.obolibrary.org/obo/GO_0042263 CHEBI:137599 biolink:ChemicalSubstance long-chain 3-oxo-fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137599 GO:0042269 biolink:BiologicalProcess regulation of natural killer cell mediated cytotoxicity Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. go-plus.json regulation of NK cell mediated cell death|regulation of NK cell mediated cytolysis|regulation of natural killer cell mediated cell death|regulation of natural killer-cell mediated cytolysis|regulation of NK cell mediated cell killing|regulation of NK cell mediated cytotoxicity|regulation of natural killer cell mediated cell killing|regulation of natural killer cell mediated cytolysis http://purl.obolibrary.org/obo/GO_0042269 GO:0032896 biolink:MolecularActivity palmitoyl-CoA 9-desaturase activity Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O. go-plus.json palmitoyl-CoA delta9-desaturase acitivity http://purl.obolibrary.org/obo/GO_0032896 CHEBI:137594 biolink:ChemicalSubstance N-acetyl-alpha-D-muramate 1-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137594 chebi_ph7_3 CHEBI:137593 biolink:ChemicalSubstance (2E,4Z)-deca-2,4-dienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137593 chebi_ph7_3 GO:0032895 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032895 GO:0032894 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032894 GO:0032893 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032893 CHEBI:137598 biolink:ChemicalSubstance 4-aminosalicylate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137598 chebi_ph7_3 GO:0032892 biolink:BiologicalProcess positive regulation of organic acid transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of organic acid transport|upregulation of organic acid transport|stimulation of organic acid transport|up-regulation of organic acid transport|activation of organic acid transport http://purl.obolibrary.org/obo/GO_0032892 OBA:0000079 biolink:OntologyClass hormone levels The amount of a hormone. go-plus.json amount of hormone http://purl.obolibrary.org/obo/OBA_0000079 GO:0032891 biolink:BiologicalProcess negative regulation of organic acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down-regulation of organic acid transport|downregulation of organic acid transport|down regulation of organic acid transport|inhibition of organic acid transport http://purl.obolibrary.org/obo/GO_0032891 GO:0032890 biolink:BiologicalProcess regulation of organic acid transport Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032890 GO:0042271 biolink:BiologicalProcess susceptibility to natural killer cell mediated cytotoxicity The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity. go-plus.json susceptibility to NK cell mediated cytotoxicity|susceptibility to NK cell mediated cell killing|susceptibility to natural killer cell mediated cell killing|susceptibility to NK cell mediated cell death|susceptibility to NK cell mediated cytolysis|susceptibility to natural killer cell mediated cytolysis|susceptibility to natural killer cell mediated cell death http://purl.obolibrary.org/obo/GO_0042271 OBA:0000066 biolink:OntologyClass direction of cell growth The direction of a cell growth. go-plus.json direction of cell growth http://purl.obolibrary.org/obo/OBA_0000066 GO:0042270 biolink:BiologicalProcess protection from natural killer cell mediated cytotoxicity The process of protecting a cell from natural killer cell mediated cytotoxicity. go-plus.json protection from NK cell mediated cell death|protection from natural killer cell mediated cell death|protection from natural killer cell mediated cytolysis|protection from NK cell mediated cytolysis|protection from NK cell mediated cytotoxicity|protection from NK cell mediated cell killing|protection from natural killer cell mediated cell killing http://purl.obolibrary.org/obo/GO_0042270 GO:0032889 biolink:BiologicalProcess regulation of vacuole fusion, non-autophagic Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0032889 GO:0032888 biolink:BiologicalProcess regulation of mitotic spindle elongation Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0032888 GO:0032887 biolink:BiologicalProcess regulation of spindle elongation Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0032887 GO:0032886 biolink:BiologicalProcess regulation of microtubule-based process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0032886 OBA:0000061 biolink:OntologyClass circulating fibrinogen levels The amount of a fibrinogen complex. go-plus.json amount of fibrinogen complex http://purl.obolibrary.org/obo/OBA_0000061 GO:0042277 biolink:MolecularActivity peptide binding Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. go-plus.json http://purl.obolibrary.org/obo/GO_0042277 goslim_chembl|goslim_pir GO:0042276 biolink:BiologicalProcess error-prone translesion synthesis The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. go-plus.json mutagenic PRR|mutagenic postreplication DNA repair|error-prone postreplication DNA repair http://purl.obolibrary.org/obo/GO_0042276 GO:0042279 biolink:MolecularActivity nitrite reductase (cytochrome, ammonia-forming) activity Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+. EC:1.7.2.2|Wikipedia:Cytochrome_c_nitrite_reductase|MetaCyc:1.7.2.2-RXN|RHEA:13089 go-plus.json multiheme nitrite reductase activity|cytochrome c nitrite reductase activity|nitrite reductase (cytochrome; ammonia-forming)|cytochrome c552 activity|ammonia:ferricytochrome-c oxidoreductase activity http://purl.obolibrary.org/obo/GO_0042279 GO:0042278 biolink:BiologicalProcess purine nucleoside metabolic process The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json purine nucleoside metabolism|purine metabolic process|purine metabolism http://purl.obolibrary.org/obo/GO_0042278 GO:0042273 biolink:BiologicalProcess ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. go-plus.json ribosomal large subunit biogenesis and assembly http://purl.obolibrary.org/obo/GO_0042273 goslim_yeast GO:0042272 biolink:CellularComponent nuclear RNA export factor complex A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm. go-plus.json Mex67-Mtr2 complex|TAP-p15 complex|NXF1-NXT1 complex http://purl.obolibrary.org/obo/GO_0042272 GO:0042275 biolink:BiologicalProcess error-free postreplication DNA repair The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate. go-plus.json error-free PRR|error-free replication restart http://purl.obolibrary.org/obo/GO_0042275 GO:0042274 biolink:BiologicalProcess ribosomal small subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis. go-plus.json ribosomal small subunit biogenesis and assembly http://purl.obolibrary.org/obo/GO_0042274 goslim_yeast GO:0032885 biolink:BiologicalProcess regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. go-plus.json http://purl.obolibrary.org/obo/GO_0032885 GO:0032884 biolink:BiologicalProcess regulation of cell wall chitin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin. go-plus.json regulation of cell wall chitin biosynthesis|regulation of cell wall chitin anabolism|regulation of cell wall chitin synthesis|regulation of cell wall chitin formation http://purl.obolibrary.org/obo/GO_0032884 GO:0032883 biolink:BiologicalProcess regulation of chitin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin. go-plus.json regulation of chitin biosynthesis|regulation of chitin anabolism|regulation of chitin synthesis|regulation of chitin formation http://purl.obolibrary.org/obo/GO_0032883 GO:0032882 biolink:BiologicalProcess regulation of chitin metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin. go-plus.json regulation of chitin metabolism http://purl.obolibrary.org/obo/GO_0032882 GO:0032881 biolink:BiologicalProcess regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. go-plus.json http://purl.obolibrary.org/obo/GO_0032881 OBA:0000068 biolink:OntologyClass endosome size The size of a endosome. go-plus.json size of endosome http://purl.obolibrary.org/obo/OBA_0000068 GO:0032880 biolink:BiologicalProcess regulation of protein localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. go-plus.json regulation of protein localisation http://purl.obolibrary.org/obo/GO_0032880 goslim_chembl OBA:0000067 biolink:OntologyClass embryonic cell shape The shape of a embryonic cell. go-plus.json shape of embryonic cell http://purl.obolibrary.org/obo/OBA_0000067 GO:0042280 biolink:MolecularActivity obsolete cell surface antigen activity, host-interacting OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition. go-plus.json cell surface antigen activity, host-interacting http://purl.obolibrary.org/obo/GO_0042280 GO:0042282 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042282 GO:0042281 biolink:MolecularActivity dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. MetaCyc:RXN-5470|EC:2.4.1.267|RHEA:30635 go-plus.json dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0042281 GO:0032879 biolink:BiologicalProcess regulation of localization Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. go-plus.json regulation of localisation http://purl.obolibrary.org/obo/GO_0032879 GO:0032878 biolink:BiologicalProcess regulation of establishment or maintenance of cell polarity Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. go-plus.json http://purl.obolibrary.org/obo/GO_0032878 GO:0032877 biolink:BiologicalProcess positive regulation of DNA endoreduplication Any process that activates or increases the frequency, rate or extent of DNA endoreduplication. go-plus.json stimulation of DNA endoreduplication|up-regulation of DNA endoreduplication|positive regulation of DNA re-duplication|positive regulation of DNA endoreplication|upregulation of DNA endoreduplication|up regulation of DNA endoreduplication|activation of DNA endoreduplication http://purl.obolibrary.org/obo/GO_0032877 GO:0032876 biolink:BiologicalProcess negative regulation of DNA endoreduplication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication. go-plus.json down-regulation of DNA endoreduplication|negative regulation of DNA re-duplication|inhibition of DNA endoreduplication|negative regulation of DNA endoreplication|down regulation of DNA endoreduplication|downregulation of DNA endoreduplication http://purl.obolibrary.org/obo/GO_0032876 GO:0032875 biolink:BiologicalProcess regulation of DNA endoreduplication Any process that modulates the frequency, rate or extent of DNA endoreduplication. go-plus.json regulation of DNA endoreplication|regulation of DNA re-duplication http://purl.obolibrary.org/obo/GO_0032875 GO:0042288 biolink:MolecularActivity MHC class I protein binding Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. go-plus.json gamma-delta T cell receptor activity|major histocompatibility complex class I binding|alpha-beta T cell receptor activity|T cell receptor activity|major histocompatibility complex class I ligand http://purl.obolibrary.org/obo/GO_0042288 GO:0042287 biolink:MolecularActivity MHC protein binding Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. go-plus.json major histocompatibility complex binding|major histocompatibility complex ligand http://purl.obolibrary.org/obo/GO_0042287 GO:0042289 biolink:MolecularActivity MHC class II protein binding Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. go-plus.json major histocompatibility complex class II binding|major histocompatibility complex class II ligand http://purl.obolibrary.org/obo/GO_0042289 GO:0042284 biolink:MolecularActivity sphingolipid delta-4 desaturase activity Catalysis of the reaction: a dihydroceramide + 2 ferrocytochrome b5 + O2 + 2 H+ -> a sphingosine ceramide (aka (4E)-sphing-4-enine ceramide) + 2 ferricytochrome b5 + 2 H2O. Reactome:R-HSA-428259|RHEA:46544|EC:1.14.19.17 go-plus.json delta-4 sphingolipid desaturase activity http://purl.obolibrary.org/obo/GO_0042284 GO:0042283 biolink:MolecularActivity dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol. MetaCyc:RXN-5471|EC:2.4.1.265|RHEA:31307 go-plus.json dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0042283 GO:0042286 biolink:MolecularActivity glutamate-1-semialdehyde 2,1-aminomutase activity Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate. EC:5.4.3.8|MetaCyc:GSAAMINOTRANS-RXN|RHEA:14265|KEGG_REACTION:R02272 go-plus.json (S)-4-amino-5-oxopentanoate 4,5-aminomutase activity|glutamate-1-semialdehyde aminotransferase activity http://purl.obolibrary.org/obo/GO_0042286 GO:0042285 biolink:MolecularActivity xylosyltransferase activity Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0042285 GO:0032874 biolink:BiologicalProcess positive regulation of stress-activated MAPK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. go-plus.json positive regulation of stress-activated MAPKKK signaling pathway|positive regulation of stress-activated MAPK signaling pathway|upregulation of stress-activated MAPK cascade|up regulation of stress-activated MAPK cascade|activation of stress-activated MAPK cascade|positive regulation of stress-activated MAPKKK cascade|stimulation of stress-activated MAPK cascade|positive regulation of p38 MAPK signaling|positive regulation of stress-activated MAPK signalling pathway|positive regulation of stress-activated MAPKKK signalling pathway|positive regulation of p38 MAPK signalling|up-regulation of stress-activated MAPK cascade http://purl.obolibrary.org/obo/GO_0032874 CHEBI:137572 biolink:ChemicalSubstance Cer(d41:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137572 chebi_ph7_3 GO:0032873 biolink:BiologicalProcess negative regulation of stress-activated MAPK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. go-plus.json negative regulation of stress-activated MAPK signaling pathway|negative regulation of stress-activated MAPKKK signaling pathway|down regulation of stress-activated MAPK cascade|downregulation of stress-activated MAPK cascade|negative regulation of p38 MAPK signaling|negative regulation of stress-activated MAPKKK signalling pathway|negative regulation of stress-activated MAPK signalling pathway|negative regulation of stress-activated MAPKKK cascade|down-regulation of stress-activated MAPK cascade|inhibition of stress-activated MAPK cascade|negative regulation of p38 MAPK signalling http://purl.obolibrary.org/obo/GO_0032873 CHEBI:137570 biolink:ChemicalSubstance Cer(d38:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137570 chebi_ph7_3 GO:0032872 biolink:BiologicalProcess regulation of stress-activated MAPK cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. go-plus.json regulation of stress-activated MAPKKK cascade|regulation of p38 MAPK signalling|regulation of stress-activated MAPKKK signaling pathway|regulation of stress-activated MAPK signaling pathway|regulation of p38 MAPK signaling|regulation of stress-activated MAPKKK signalling pathway|regulation of stress-activated MAPK signalling pathway http://purl.obolibrary.org/obo/GO_0032872 GO:0032871 biolink:BiologicalProcess regulation of karyogamy Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0032871 GO:0032870 biolink:BiologicalProcess cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032870 CHEBI:137574 biolink:ChemicalSubstance Cer(d44:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137574 chebi_ph7_3 GO:0042291 biolink:MolecularActivity obsolete Hub1 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json Hub1 hydrolase activity http://purl.obolibrary.org/obo/GO_0042291 GO:0042290 biolink:MolecularActivity obsolete URM1 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json URM1 hydrolase activity http://purl.obolibrary.org/obo/GO_0042290 GO:0042293 biolink:MolecularActivity Hub1 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json http://purl.obolibrary.org/obo/GO_0042293 GO:0032869 biolink:BiologicalProcess cellular response to insulin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0032869 GO:0032868 biolink:BiologicalProcess response to insulin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. go-plus.json response to insulin stimulus http://purl.obolibrary.org/obo/GO_0032868 GO:0042292 biolink:MolecularActivity URM1 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json http://purl.obolibrary.org/obo/GO_0042292 GO:0032867 biolink:MolecularActivity L-arabinose:NADP reductase activity Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+. MetaCyc:RXN-8772|RHEA:25229|SABIO-RK:1858|KEGG_REACTION:R01759 go-plus.json arabinose reductase activity|arabinose:NADP reductase activity http://purl.obolibrary.org/obo/GO_0032867 GO:0032866 biolink:MolecularActivity D-xylose:NADP reductase activity Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+. MetaCyc:RXN-8773|RHEA:27445 go-plus.json xylose reductase activity|D-xylose reductase activity http://purl.obolibrary.org/obo/GO_0032866 GO:0032865 biolink:CellularComponent ERMES complex A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. go-plus.json mitochore|ER-mitochondria encounter structure|Mdm10/Mdm12/Mmm1 complex|MMM1 complex http://purl.obolibrary.org/obo/GO_0032865 GO:0032864 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032864 GO:0042299 biolink:MolecularActivity lupeol synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol. EC:5.4.99.41|MetaCyc:RXN-111|RHEA:31383 go-plus.json oxidosqualene:lupeol cyclase activity http://purl.obolibrary.org/obo/GO_0042299 GO:0042298 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042298 GO:0042295 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042295 GO:0042294 biolink:MolecularActivity URM1 transferase activity Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y --> Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0042294 GO:0042297 biolink:BiologicalProcess vocal learning A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others. Wikipedia:Vocal_learning go-plus.json http://purl.obolibrary.org/obo/GO_0042297 GO:0042296 biolink:MolecularActivity ISG15 transferase activity Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y --> Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages. Reactome:R-HSA-5653754 go-plus.json ISG15 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0042296 GO:0032863 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032863 CHEBI:137583 biolink:ChemicalSubstance 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137583 chebi_ph7_3 GO:0032862 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032862 CHEBI:137582 biolink:ChemicalSubstance 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-icosatetraenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137582 chebi_ph7_3 GO:0032861 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032861 CHEBI:137581 biolink:ChemicalSubstance 2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137581 chebi_ph7_3 GO:0032860 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032860 CHEBI:137580 biolink:ChemicalSubstance 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-icosatetraenoyl]-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_137580 chebi_ph7_3 CHEBI:137586 biolink:ChemicalSubstance alkyl,acylglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_137586 chebi_ph7_3 CHEBI:137585 biolink:ChemicalSubstance 2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137585 chebi_ph7_3 CHEBI:137584 biolink:ChemicalSubstance 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137584 chebi_ph7_3 GO:0032859 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032859 GO:0032858 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032858 GO:0032857 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032857 GO:0032856 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032856 GO:0032855 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032855 GO:0032854 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032854 GO:0032853 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032853 CHEBI:137558 biolink:ChemicalSubstance 2-O-[alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137558 CHEBI:137550 biolink:ChemicalSubstance N-(fatty acyl)-L-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137550 GO:0032852 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032852 GO:0032851 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032851 GO:0032850 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032850 CHEBI:3163 biolink:ChemicalSubstance bracteatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3163 chebi_ph7_3 CHEBI:3165 biolink:ChemicalSubstance bradykinin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3165 CHEBI:137553 biolink:ChemicalSubstance 2-O-[6-O-octanoyl-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glyceric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137553 GO:0032849 biolink:BiologicalProcess positive regulation of cellular pH reduction Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell. go-plus.json positive regulation of reduction of pH in cell|upregulation of cellular pH reduction|positive regulation of cell pH reduction|positive regulation of reduction of cellular pH|positive regulation of intracellular acidification|up regulation of cellular pH reduction|activation of cellular pH reduction|positive regulation of cellular acidification|stimulation of cellular pH reduction|positive regulation of intracellular pH reduction|up-regulation of cellular pH reduction http://purl.obolibrary.org/obo/GO_0032849 GO:0032848 biolink:BiologicalProcess negative regulation of cellular pH reduction Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell. go-plus.json negative regulation of reduction of pH in cell|down regulation of cellular pH reduction|negative regulation of reduction of cellular pH|downregulation of cellular pH reduction|negative regulation of cell pH reduction|negative regulation of cellular acidification|negative regulation of intracellular acidification|down-regulation of cellular pH reduction|negative regulation of intracellular pH reduction|inhibition of cellular pH reduction http://purl.obolibrary.org/obo/GO_0032848 GO:0032847 biolink:BiologicalProcess regulation of cellular pH reduction Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell. go-plus.json regulation of cell pH reduction|regulation of intracellular pH reduction|regulation of intracellular acidification|regulation of reduction of cellular pH|regulation of reduction of pH in cell|regulation of cellular acidification http://purl.obolibrary.org/obo/GO_0032847 GO:0032846 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032846 GO:0032845 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032845 GO:0032844 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032844 GO:0032843 biolink:MolecularActivity hydroperoxide reductase activity Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol. go-plus.json http://purl.obolibrary.org/obo/GO_0032843 GO:0032842 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032842 CHEBI:137569 biolink:ChemicalSubstance Cer(d34:1) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137569 chebi_ph7_3 CHEBI:3179 biolink:ChemicalSubstance bromobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_3179 chebi_ph7_3 CHEBI:137568 biolink:ChemicalSubstance Cer(d34:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137568 chebi_ph7_3 CHEBI:137567 biolink:ChemicalSubstance 11(S)-HETE(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137567 chebi_ph7_3 CHEBI:137566 biolink:ChemicalSubstance EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_137566 GO:0032841 biolink:MolecularActivity calcitonin binding Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid. go-plus.json http://purl.obolibrary.org/obo/GO_0032841 GO:0032840 biolink:MolecularActivity intramolecular proline-rich ligand binding Binding to a proline-rich region within the same polypeptide. go-plus.json intramolecular proline-rich region binding http://purl.obolibrary.org/obo/GO_0032840 CHEBI:137565 biolink:ChemicalSubstance (3E,7E)-dolabella-3,7-dien-18-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137565 chebi_ph7_3 CHEBI:137564 biolink:ChemicalSubstance (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137564 chebi_ph7_3 CHEBI:137563 biolink:ChemicalSubstance (1R,4R,5S)-(-)-guaia-6,10(14)-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137563 chebi_ph7_3 CHEBI:137562 biolink:ChemicalSubstance (+)-eremophilene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137562 chebi_ph7_3 OBO:GOCHE_48705 biolink:OntologyClass substance with agonist role go-plus.json http://purl.obolibrary.org/obo/GOCHE_48705 3_STAR CHEBI:80489 biolink:ChemicalSubstance desmethylxanthohumol go-plus.json http://purl.obolibrary.org/obo/CHEBI_80489 GO:0140706 biolink:BiologicalProcess protein-containing complex localization to centriolar satellite A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite. go-plus.json http://purl.obolibrary.org/obo/GO_0140706 GO:0042200 biolink:BiologicalProcess cyanuric acid catabolic process The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides. UM-BBD_pathwayID:cya go-plus.json cyanuric acid catabolism|cyanuric acid degradation|cyanuric acid breakdown http://purl.obolibrary.org/obo/GO_0042200 GO:0042202 biolink:BiologicalProcess N-cyclopropylmelamine catabolic process The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide. UM-BBD_pathwayID:cpm go-plus.json N-cyclopropylmelamine degradation|cyromazine catabolic process|N-cyclopropylmelamine catabolism|N-cyclopropylmelamine breakdown|cyromazine catabolism http://purl.obolibrary.org/obo/GO_0042202 GO:0140700 biolink:MolecularActivity 3',2'-cyclic GMP-AMP synthase activity Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP). go-plus.json 3',2'-cyclic GAMP synthase activity|3',2' cyclic-GMP-AMP synthase activity http://purl.obolibrary.org/obo/GO_0140700 GO:0042201 biolink:BiologicalProcess N-cyclopropylmelamine metabolic process The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide. go-plus.json cyromazine metabolism|cyromazine metabolic process|N-cyclopropylmelamine metabolism http://purl.obolibrary.org/obo/GO_0042201 GO:0140702 biolink:MolecularActivity cyclic GMP-AMP binding Binding to cyclic GMP-AMP (cGAMP) nucleotide. go-plus.json http://purl.obolibrary.org/obo/GO_0140702 gocheck_do_not_annotate GO:0140701 biolink:MolecularActivity 3',3'-cyclic GMP-AMP synthase activity Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP). RHEA:35647 go-plus.json 3',3'-cyclic GAMP synthase activity|3',3' cyclic-GMP-AMP synthase activity|3',3' cyclic-GAMP synthase activity http://purl.obolibrary.org/obo/GO_0140701 GO:0140704 biolink:MolecularActivity 3',2'-cyclic GMP-AMP binding Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages. go-plus.json 3',2'-cyclic GAMP binding|3',2'-cGAMP binding|3',2' cyclic-GMP-AMP binding http://purl.obolibrary.org/obo/GO_0140704 GO:0140703 biolink:MolecularActivity 3',3'-cyclic GMP-AMP binding Binding to 3',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 3',5' linkages. go-plus.json 3',3'-cyclic GAMP binding|3',3' cyclic-GMP-AMP binding|3',3'-cGMP-AMP binding|3',3'-cGAMP binding http://purl.obolibrary.org/obo/GO_0140703 GO:0042208 biolink:BiologicalProcess propylene catabolic process The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. UM-BBD_pathwayID:pro go-plus.json propylene degradation|propylene catabolism|propylene breakdown http://purl.obolibrary.org/obo/GO_0042208 GO:0042207 biolink:BiologicalProcess styrene catabolic process The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene. UM-BBD_pathwayID:sty go-plus.json styrene breakdown|styrene catabolism|styrene degradation http://purl.obolibrary.org/obo/GO_0042207 GO:0042209 biolink:BiologicalProcess orcinol catabolic process The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants. UM-BBD_pathwayID:orc go-plus.json orcinol breakdown|orcin catabolic process|orcinol catabolism|orcin catabolism|orcinol degradation http://purl.obolibrary.org/obo/GO_0042209 GO:0042204 biolink:BiologicalProcess s-triazine compound catabolic process The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms. UM-BBD_pathwayID:tria go-plus.json s-triazine compound degradation|s-triazine compound catabolism|s-triazine compound breakdown http://purl.obolibrary.org/obo/GO_0042204 GO:0042203 biolink:BiologicalProcess toluene catabolic process The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products. go-plus.json toluene degradation|toluene breakdown|toluene catabolism http://purl.obolibrary.org/obo/GO_0042203 GO:0042206 biolink:BiologicalProcess halogenated hydrocarbon catabolic process The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. go-plus.json halogenated hydrocarbon catabolism|halogenated hydrocarbon degradation|halogenated hydrocarbon breakdown http://purl.obolibrary.org/obo/GO_0042206 GO:0042205 biolink:BiologicalProcess chlorinated hydrocarbon catabolic process The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms. go-plus.json chlorinated hydrocarbon breakdown|chlorinated hydrocarbon catabolism|chlorinated hydrocarbon degradation http://purl.obolibrary.org/obo/GO_0042205 NCBITaxon:8825 biolink:OrganismalEntity Neognathae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_8825 GO:0042211 biolink:BiologicalProcess dimethylsilanediol catabolic process The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products. go-plus.json dimethylsilanediol degradation|dimethylsilanediol breakdown|dimethylsilanediol catabolism|catabolic process of DMSD|degradation of dimethylsilanediol|catabolism of DMSD http://purl.obolibrary.org/obo/GO_0042211 GO:0042210 biolink:BiologicalProcess octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter. UM-BBD_pathwayID:osi go-plus.json octamethylcyclotetrasiloxane degradation to dimethylsilanediol|octamethylcyclotetrasiloxane breakdown to dimethylsilanediol|catabolic process of octamethylcyclotetrasiloxane to DMSD|catabolism of octamethylcyclotetrasiloxane to DMSD http://purl.obolibrary.org/obo/GO_0042210 GO:0042213 biolink:BiologicalProcess m-cresol catabolic process The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol. MetaCyc:M-CRESOL-DEGRADATION-PWY|UM-BBD_pathwayID:mcr go-plus.json 3-hydroxytoluene catabolism|meta-cresol catabolism|m-cresol degradation|meta-cresol catabolic process|3-hydroxytoluene catabolic process|m-cresol breakdown|m-cresol catabolism http://purl.obolibrary.org/obo/GO_0042213 GO:0042212 biolink:BiologicalProcess cresol metabolic process The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote. go-plus.json cresol metabolism|hydroxytoluene metabolic process|hydroxytoluene metabolism http://purl.obolibrary.org/obo/GO_0042212 GO:0042219 biolink:BiologicalProcess cellular modified amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. go-plus.json cellular amino acid derivative breakdown|modified amino acid catabolic process|cellular amino acid derivative catabolic process|cellular modified amino acid catabolism|amino acid derivative catabolic process|cellular modified amino acid degradation|cellular modified amino acid breakdown|cellular amino acid derivative catabolism|cellular amino acid derivative degradation|modified amino acid catabolism http://purl.obolibrary.org/obo/GO_0042219 GO:0042218 biolink:BiologicalProcess 1-aminocyclopropane-1-carboxylate biosynthetic process The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. go-plus.json 1-aminocyclopropane-1-carboxylate biosynthesis|1-aminocyclopropane-1-carboxylate anabolism|1-aminocyclopropane-1-carboxylate synthesis|1-aminocyclopropane-1-carboxylate formation http://purl.obolibrary.org/obo/GO_0042218 GO:0042215 biolink:BiologicalProcess anaerobic phenol-containing compound metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen. UM-BBD_pathwayID:phe go-plus.json anaerobic phenol-containing compound metabolism http://purl.obolibrary.org/obo/GO_0042215 GO:0042214 biolink:BiologicalProcess terpene metabolic process The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups. go-plus.json terpene metabolism http://purl.obolibrary.org/obo/GO_0042214 GO:0042217 biolink:BiologicalProcess 1-aminocyclopropane-1-carboxylate catabolic process The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. go-plus.json 1-aminocyclopropane-1-carboxylate degradation|1-aminocyclopropane-1-carboxylate catabolism|1-aminocyclopropane-1-carboxylate breakdown http://purl.obolibrary.org/obo/GO_0042217 GO:0042216 biolink:BiologicalProcess phenanthrene catabolic process The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon. UM-BBD_pathwayID:phe go-plus.json phenanthrene breakdown|phenanthrene catabolism|phenanthrene degradation http://purl.obolibrary.org/obo/GO_0042216 GO:0042222 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042222 GO:0042221 biolink:BiologicalProcess response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. go-plus.json response to chemical stimulus|response to chemical substance http://purl.obolibrary.org/obo/GO_0042221 goslim_yeast|goslim_candida|gocheck_do_not_manually_annotate|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_aspergillus GO:0042224 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042224 GO:0042223 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042223 GO:0042220 biolink:BiologicalProcess response to cocaine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. go-plus.json http://purl.obolibrary.org/obo/GO_0042220 GO:0042229 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042229 GO:0042226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042226 GO:0042225 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042225 GO:0042228 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042228 GO:0042227 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042227 GO:0042233 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042233 GO:0042232 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042232 GO:0042235 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042235 GO:0042234 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042234 NCBITaxon:862507 biolink:OrganismalEntity Mus go-plus.json Mus http://purl.obolibrary.org/obo/NCBITaxon_862507 GO:0042231 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042231 GO:0042230 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042230 GO:0042237 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042237 GO:0042236 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042236 GO:0042239 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042239 GO:0042238 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042238 CHEBI:31459 biolink:ChemicalSubstance 3,7,12-trioxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31459 CHEBI:55429 biolink:ChemicalSubstance cephamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_55429 CHEBI:31457 biolink:ChemicalSubstance decanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_31457 chebi_ph7_3 GO:0150156 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150156 GO:0150155 biolink:BiologicalProcess interleukin-34 production The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0150155 gocheck_do_not_annotate GO:0150154 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150154 GO:0150153 biolink:BiologicalProcess positive regulation of interleukin-17A production Any process that activates or increases the frequency, rate or extent of interleukin-17A production. go-plus.json positive regulation of interleukin-17A biosynthetic process http://purl.obolibrary.org/obo/GO_0150153 GO:0150152 biolink:BiologicalProcess negative regulation of interleukin-17A production Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production. go-plus.json negative regulation of interleukin-17A biosynthetic process http://purl.obolibrary.org/obo/GO_0150152 GO:0150151 biolink:BiologicalProcess regulation of interleukin-17A production Any process that modulates the frequency, rate or extent of interleukin-17A production. go-plus.json regulation of interleukin-17A biosynthetic process http://purl.obolibrary.org/obo/GO_0150151 GO:0150150 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150150 UBERON:0006682 biolink:AnatomicalEntity hypoglossal canal The hypoglossal canal is a bony canal in the occipital bone of the skull. go-plus.json anterior condylar canal|hyperglossal canal|canalis nervi hypoglossi http://purl.obolibrary.org/obo/UBERON_0006682 GO:0150159 biolink:BiologicalProcess negative regulation of interleukin-34 production Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production. go-plus.json negative regulation of interleukin-34 biosynthetic process http://purl.obolibrary.org/obo/GO_0150159 GO:0150158 biolink:BiologicalProcess positive regulation of interleukin-34 production Any process that activates or increases the frequency, rate or extent of interleukin-34 production. go-plus.json positive regulation of interleukin-34 biosynthetic process http://purl.obolibrary.org/obo/GO_0150158 GO:0150157 biolink:BiologicalProcess regulation of interleukin-34 production Any process that modulates the frequency, rate or extent of interleukin-34 production. go-plus.json regulation of interleukin-34 biosynthetic process|interleukin-34 biosynthetic process http://purl.obolibrary.org/obo/GO_0150157 NCBITaxon:162425 biolink:OrganismalEntity Aspergillus nidulans go-plus.json Emericella nidulans|Aspergillus nidulellus http://purl.obolibrary.org/obo/NCBITaxon_162425 UBERON:0006686 biolink:AnatomicalEntity spinal vein A vein that is part of a vertebral column. go-plus.json spinal branch|vena spinalis http://purl.obolibrary.org/obo/UBERON_0006686 CHEBI:55415 biolink:ChemicalSubstance N-acyl-D-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55415 CHEBI:31469 biolink:ChemicalSubstance desmethyldescarbamoylnovobiocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31469 CHEBI:55417 biolink:ChemicalSubstance maleimides go-plus.json http://purl.obolibrary.org/obo/CHEBI_55417 GO:0150167 biolink:BiologicalProcess positive regulation of histone H3-K4 acetylation Any process that activates or increases the frequency, rate or extent of histone H3-K4 acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_0150167 GO:0150166 biolink:BiologicalProcess regulation of histone H3-K4 acetylation Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_0150166 GO:0150165 biolink:BiologicalProcess miRNA-mediated inhibition of transcription by RNA polymerase II Any process mediated by a microRNA (miRNA) that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0150165 GO:0150164 biolink:BiologicalProcess miRNA-mediated regulation of transcription by RNA polymerase II Any process mediated by a microRNA (miRNA) that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0150164 GO:0150163 biolink:BiologicalProcess miRNA-mediated activation of transcription by RNA polymerase II Any process mediated by a microRNA (miRNA) that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0150163 GO:0150162 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150162 GO:0150161 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150161 GO:0150160 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150160 UBERON:0006671 biolink:AnatomicalEntity orbital fat pad A fat pad that is part of a orbital region. go-plus.json orbital fat body|retrobulbar fat|orbital fat|intraorbital fat pad http://purl.obolibrary.org/obo/UBERON_0006671 UBERON:0006670 biolink:AnatomicalEntity central tendon of diaphragm the three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers go-plus.json centrum tendineum diaphragmatis|centrum tendineum|central tendon http://purl.obolibrary.org/obo/UBERON_0006670 GO:0150169 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150169 GO:0150168 biolink:BiologicalProcess negative regulation of histone H3-K4 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_0150168 CHEBI:31467 biolink:ChemicalSubstance descarbamoylnovobiocin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31467 CHEBI:55412 biolink:ChemicalSubstance N-acyl-L-homoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55412 CHEBI:55414 biolink:ChemicalSubstance N-acylhomoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55414 NCBITaxon:1307796 biolink:OrganismalEntity Chenopodioideae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1307796 UBERON:0006678 biolink:AnatomicalEntity foramen secundum A foramen in the septum secundum. go-plus.json ostium secundum|foramen secundum http://purl.obolibrary.org/obo/UBERON_0006678 CHEBI:31463 biolink:ChemicalSubstance delphinidin 3-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_31463 UBERON:0006677 biolink:AnatomicalEntity surface of epithelium An anatomical boundary that adjacent_to a epithelium. go-plus.json epithelium surface http://purl.obolibrary.org/obo/UBERON_0006677 CHEBI:55410 biolink:ChemicalSubstance anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) go-plus.json http://purl.obolibrary.org/obo/CHEBI_55410 UBERON:0006675 biolink:AnatomicalEntity venous valve A valve that is part of a vein. go-plus.json valve of vein http://purl.obolibrary.org/obo/UBERON_0006675 CHEBI:55409 biolink:ChemicalSubstance 6-iminocyclohexa-2,4-dienone go-plus.json http://purl.obolibrary.org/obo/CHEBI_55409 chebi_ph7_3 CHEBI:55404 biolink:ChemicalSubstance N-acetyl-D-galactosamine 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55404 CHEBI:55406 biolink:ChemicalSubstance beta-D-apiofuranosyl-(1->6)-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55406 chebi_ph7_3 GO:0150134 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150134 GO:0150133 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150133 GO:0150132 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150132 GO:0150131 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150131 GO:0150130 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150130 GO:0150139 biolink:BiologicalProcess positive regulation of interleukin-37 production Any process that activates or increases the frequency, rate or extent of interleukin-37 production. go-plus.json positive regulation of interleukin-37 biosynthetic process http://purl.obolibrary.org/obo/GO_0150139 UBERON:0006660 biolink:AnatomicalEntity muscular coat A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis. go-plus.json muscular layer|tunica muscularis|transverse muscular fibers|muscularis propria|tunica muscularis|muscularis externa|muscularis|muscularis layer|muscular coat|tunica externa http://purl.obolibrary.org/obo/UBERON_0006660 GO:0150138 biolink:BiologicalProcess negative regulation of interleukin-37 production Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production. go-plus.json negative regulation of interleukin-37 biosynthetic process http://purl.obolibrary.org/obo/GO_0150138 GO:0150137 biolink:BiologicalProcess interleukin-37 production The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json interleukin-37 biosynthetic process http://purl.obolibrary.org/obo/GO_0150137 gocheck_do_not_annotate GO:0150136 biolink:BiologicalProcess regulation of interleukin-37 production Any process that modulates the frequency, rate or extent of interleukin-37 production. go-plus.json regulation of interleukin-37 biosynthetic process http://purl.obolibrary.org/obo/GO_0150136 GO:0150135 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150135 CHEBI:55400 biolink:ChemicalSubstance 3-dehydropyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55400 CHEBI:31432 biolink:ChemicalSubstance corynebactin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31432 chebi_ph7_3 UBERON:0006668 biolink:AnatomicalEntity carotid canal On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]. go-plus.json canalis caroticus http://purl.obolibrary.org/obo/UBERON_0006668 CHEBI:55402 biolink:ChemicalSubstance 3-dehydro-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55402 chebi_ph7_3 GO:0150145 biolink:BiologicalProcess positive regulation of CD80 production Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process. go-plus.json positive regulation of CD80 biosynthetic process http://purl.obolibrary.org/obo/GO_0150145 GO:0150144 biolink:BiologicalProcess negative regulation of CD80 production Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process. go-plus.json negative regulation of CD80 biosynthetic process http://purl.obolibrary.org/obo/GO_0150144 GO:0150143 biolink:BiologicalProcess regulation of CD80 production Any process that modulates the frequency, rate or extent of CD80 biosynthetic process. go-plus.json regulation of CD80 biosynthetic process http://purl.obolibrary.org/obo/GO_0150143 GO:0150142 biolink:BiologicalProcess positive regulation of CD86 production Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process. go-plus.json positive regulation of CD86 biosynthetic process http://purl.obolibrary.org/obo/GO_0150142 GO:0150141 biolink:BiologicalProcess negative regulation of CD86 production Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process. go-plus.json negative regulation of CD86 biosynthetic process http://purl.obolibrary.org/obo/GO_0150141 GO:0150140 biolink:BiologicalProcess regulation of CD86 production Any process that modulates the frequency, rate or extent of CD86 biosynthetic process. go-plus.json regulation of CD86 biosynthetic process http://purl.obolibrary.org/obo/GO_0150140 UBERON:0006652 biolink:AnatomicalEntity muscular layer of vagina go-plus.json vaginal muscularis|tunica muscularis vaginae|muscular coat of vagina http://purl.obolibrary.org/obo/UBERON_0006652 GO:0150149 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150149 GO:0150148 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150148 GO:0150147 biolink:BiologicalProcess cell-cell junction disassembly The disaggregation of a cell-cell junction into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0150147 GO:0150146 biolink:BiologicalProcess cell junction disassembly The disaggregation of a cell junction into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0150146 CHEBI:31445 biolink:ChemicalSubstance cyclic ADP-ribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_31445 UBERON:0006658 biolink:AnatomicalEntity interphalangeal joint A joint that connects one phalanx to another along a proximodistal axis. go-plus.json inter-phalanx joint|inter-phalangeal joint http://purl.obolibrary.org/obo/UBERON_0006658 UBERON:0006657 biolink:AnatomicalEntity glenoid fossa Anatomical cavity for the proximal articular surface of the proximal limb or fin element with the scapulocoracoid or equivalent structure. go-plus.json glenoid cavity of scapula|cavitas glenoidalis|glenoid cavity|glenoid cavity|cavitas glenoidalis scapulae|glenoid facet|cavitus glenoidalis http://purl.obolibrary.org/obo/UBERON_0006657 UBERON:0006653 biolink:AnatomicalEntity glans clitoris Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]. go-plus.json clitoris glans|glans clitoris|glans clitoridis|glans of clitoris http://purl.obolibrary.org/obo/UBERON_0006653 GO:0150112 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150112 GO:0150111 biolink:BiologicalProcess regulation of transepithelial transport Any process that modulates the frequency, rate or extent of transepithelial transport. go-plus.json http://purl.obolibrary.org/obo/GO_0150111 GO:0150110 biolink:BiologicalProcess negative regulation of cholesterol esterification Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol esterification. go-plus.json http://purl.obolibrary.org/obo/GO_0150110 GO:0150119 biolink:BiologicalProcess negative regulation of protein localization to cell-cell junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. go-plus.json negative regulation of protein localisation to cell-cell junction http://purl.obolibrary.org/obo/GO_0150119 GO:0150118 biolink:BiologicalProcess negative regulation of cell-substrate junction organization Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization. go-plus.json http://purl.obolibrary.org/obo/GO_0150118 GO:0150117 biolink:BiologicalProcess positive regulation of cell-substrate junction organization Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization. go-plus.json http://purl.obolibrary.org/obo/GO_0150117 GO:0150116 biolink:BiologicalProcess regulation of cell-substrate junction organization Any process that modulates the frequency, rate or extent of cell-substrate junction organization. go-plus.json http://purl.obolibrary.org/obo/GO_0150116 GO:0150115 biolink:BiologicalProcess cell-substrate junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0150115 GO:0150114 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150114 GO:0150113 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150113 GO:0150123 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150123 GO:0150122 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150122 GO:0150121 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150121 GO:0150120 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150120 GO:0150129 biolink:BiologicalProcess positive regulation of interleukin-33 production Any process that activates or increases the frequency, rate or extent of interleukin-33 production. go-plus.json positive regulation of interleukin-33 biosynthetic process|positive regulation of interleukin-33 secretion http://purl.obolibrary.org/obo/GO_0150129 GO:0150128 biolink:BiologicalProcess negative regulation of interleukin-33 production Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production. go-plus.json negative regulation of interleukin-33 secretion|negative regulation of interleukin-33 biosynthetic process http://purl.obolibrary.org/obo/GO_0150128 GO:0150127 biolink:BiologicalProcess regulation of interleukin-33 production Any process that modulates the frequency, rate or extent of interleukin-33 production. go-plus.json regulation of interleukin-33 biosynthetic process|regulation of interleukin-33 secretion http://purl.obolibrary.org/obo/GO_0150127 GO:0150126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150126 GO:0150125 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150125 GO:0150124 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150124 NCBITaxon:162484 biolink:OrganismalEntity Pucciniomycetes go-plus.json Urediniomycetidae http://purl.obolibrary.org/obo/NCBITaxon_162484 CHEBI:31402 biolink:ChemicalSubstance cinnamyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31402 chebi_ph7_3 GO:0150101 biolink:BiologicalProcess regulation of microtubule anchoring at centrosome Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0150101 GO:0150100 biolink:MolecularActivity RNA binding involved in posttranscriptional gene silencing Any RNA binding that is involved in posttranscriptional gene silencing. go-plus.json RNA binding involved in quelling|RNA binding involved in post-transcriptional gene silencing|RNA binding involved in cosuppression|RNA binding involved in PTGS http://purl.obolibrary.org/obo/GO_0150100 UBERON:0006696 biolink:AnatomicalEntity mammillothalamic axonal tract A fiber pathway that originates from neurons in the posterior hypothalamic region and projects to various nuclei of the anterior nuclear group of the thalamus. It is a composite structure that consists of the mammillothalamic tract of the hypothalamus and the mammillothalamic tract of the thalamus (Carpenter-1983). (from Brain Info.org) go-plus.json thalamomammillary fasciculus|fasciculus mammillothalamicus|mammillo-thalamic fasciculus|mammillothalamic fasciculus|bundle of vicq d%e2%80%99azyr|mammillothalamic tract|mammillothalamic tract|bundle of vicq d%27azyr|mammillo-thalamic tract|fasciculus mammillothalamicus|vicq d'azyr's bundle|mamillo-thalamic tract http://purl.obolibrary.org/obo/UBERON_0006696 UBERON:0006695 biolink:AnatomicalEntity mammillary axonal complex The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006695 GO:0150107 biolink:BiologicalProcess positive regulation of protein localization to cell-cell junction Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. go-plus.json http://purl.obolibrary.org/obo/GO_0150107 UBERON:0006694 biolink:AnatomicalEntity cerebellum vasculature A vasculature that is part of a cerebellum. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006694 GO:0150106 biolink:BiologicalProcess regulation of protein localization to cell-cell junction Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. go-plus.json http://purl.obolibrary.org/obo/GO_0150106 UBERON:0006692 biolink:AnatomicalEntity vertebral canal A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes. go-plus.json neural canal|foramen vertebrale|vertebral canal|spinal cavity|spinal canal|c. vertebralis http://purl.obolibrary.org/obo/UBERON_0006692 GO:0150105 biolink:BiologicalProcess protein localization to cell-cell junction A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. go-plus.json http://purl.obolibrary.org/obo/GO_0150105 GO:0150104 biolink:BiologicalProcess transport across blood-brain barrier The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier. go-plus.json transport across blood brain barrier|transport across BBB http://purl.obolibrary.org/obo/GO_0150104 GO:0150103 biolink:BiologicalProcess reactive gliosis A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells. go-plus.json gliosis http://purl.obolibrary.org/obo/GO_0150103 GO:0150102 biolink:BiologicalProcess negative regulation of monocyte activation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation. go-plus.json repression of monocyte activation http://purl.obolibrary.org/obo/GO_0150102 UBERON:0006698 biolink:AnatomicalEntity mammillotegmental axonal tract The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons go-plus.json tractus hypothalamotegmentalis|tractus mammillotegmentalis|mammillotegmental tract of hypothalamus|mammillo-tegmental tract|mammillotegmental tract|tractus hypothalamicotegmentalis|medial tegmental tract|mammillotegmental fasciculus|MTG|mammillotegmental tract (Gudden)|fasciculus mamillotegmentalis|Gudden tract|tractus mamillo-tegmentalis|von Gudden's tract http://purl.obolibrary.org/obo/UBERON_0006698 UBERON:0006697 biolink:AnatomicalEntity mammillotectal axonal tract The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006697 GO:0032838 biolink:CellularComponent plasma membrane bounded cell projection cytoplasm All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. go-plus.json http://purl.obolibrary.org/obo/GO_0032838 GO:0032837 biolink:BiologicalProcess distributive segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally. go-plus.json http://purl.obolibrary.org/obo/GO_0032837 GO:0032836 biolink:BiologicalProcess glomerular basement membrane development The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. go-plus.json http://purl.obolibrary.org/obo/GO_0032836 GO:0032835 biolink:BiologicalProcess glomerulus development The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. go-plus.json glomerular development http://purl.obolibrary.org/obo/GO_0032835 GO:0032834 biolink:BiologicalProcess positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response. go-plus.json positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0032834 GO:0032833 biolink:BiologicalProcess negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response. go-plus.json negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0032833 GO:0032832 biolink:BiologicalProcess regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response. go-plus.json regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0032832 GO:0032831 biolink:BiologicalProcess positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. go-plus.json up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0032831 GO:0032839 biolink:CellularComponent dendrite cytoplasm All of the contents of a dendrite, excluding the surrounding plasma membrane. go-plus.json dendritic cytoplasm http://purl.obolibrary.org/obo/GO_0032839 GO:0032830 biolink:BiologicalProcess negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. go-plus.json negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation http://purl.obolibrary.org/obo/GO_0032830 OBA:0000138 biolink:OntologyClass spindle density The amount of a spindle. go-plus.json amount of spindle http://purl.obolibrary.org/obo/OBA_0000138 UBERON:0006603 biolink:AnatomicalEntity presumptive mesoderm Presumptive structure of the blastula that will develop into mesoderm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006603 OBA:0000139 biolink:OntologyClass synapse structure and activity The quality of a synapse. go-plus.json quality of synapse http://purl.obolibrary.org/obo/OBA_0000139 UBERON:0006601 biolink:AnatomicalEntity presumptive ectoderm Presumptive structure of the blastula that will develop into ectoderm. go-plus.json presumptive epidermis http://purl.obolibrary.org/obo/UBERON_0006601 OBA:0000134 biolink:OntologyClass resting membrane potential go-plus.json http://purl.obolibrary.org/obo/OBA_0000134 UBERON:0006600 biolink:AnatomicalEntity presumptive enteric nervous system go-plus.json future enteric nervous system http://purl.obolibrary.org/obo/UBERON_0006600 CHEBI:137652 biolink:ChemicalSubstance N-acetyl-L-alpha-phenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137652 OBA:0000136 biolink:OntologyClass short-term neuronal synaptic plasticity go-plus.json http://purl.obolibrary.org/obo/OBA_0000136 CHEBI:137650 biolink:ChemicalSubstance short-chain (3S)-hydroxy fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137650 GO:0032827 biolink:BiologicalProcess negative regulation of natural killer cell differentiation involved in immune response Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response. go-plus.json negative regulation of natural killer cell differentiation during immune response|down-regulation of natural killer cell differentiation during immune response|negative regulation of NK cell differentiation during immune response|inhibition of natural killer cell differentiation during immune response|downregulation of natural killer cell differentiation during immune response|down regulation of natural killer cell differentiation during immune response|negative regulation of natural killer cell development involved in immune response http://purl.obolibrary.org/obo/GO_0032827 GO:0032826 biolink:BiologicalProcess regulation of natural killer cell differentiation involved in immune response Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response. go-plus.json regulation of natural killer cell development involved in immune response|regulation of natural killer cell differentiation during immune response|regulation of NK cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0032826 GO:0032825 biolink:BiologicalProcess positive regulation of natural killer cell differentiation Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation. go-plus.json upregulation of natural killer cell differentiation|positive regulation of NK cell differentiation|up regulation of natural killer cell differentiation|positive regulation of natural killer cell development|activation of natural killer cell differentiation|stimulation of natural killer cell differentiation|up-regulation of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0032825 OBA:0000121 biolink:OntologyClass pH go-plus.json http://purl.obolibrary.org/obo/OBA_0000121 GO:0032824 biolink:BiologicalProcess negative regulation of natural killer cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation. go-plus.json down regulation of natural killer cell differentiation|downregulation of natural killer cell differentiation|negative regulation of NK cell differentiation|negative regulation of natural killer cell development|down-regulation of natural killer cell differentiation|inhibition of natural killer cell differentiation http://purl.obolibrary.org/obo/GO_0032824 GO:0032823 biolink:BiologicalProcess regulation of natural killer cell differentiation Any process that modulates the frequency, rate or extent of natural killer cell differentiation. go-plus.json regulation of NK cell differentiation|regulation of natural killer cell development http://purl.obolibrary.org/obo/GO_0032823 GO:0032822 biolink:BiologicalProcess positive regulation of natural killer cell proliferation involved in immune response Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response. go-plus.json activation of natural killer cell proliferation during immune response|up-regulation of natural killer cell proliferation during immune response|positive regulation of natural killer cell proliferation during immune response|up regulation of natural killer cell proliferation during immune response|positive regulation of NK cell proliferation during immune response|upregulation of natural killer cell proliferation during immune response|stimulation of natural killer cell proliferation during immune response http://purl.obolibrary.org/obo/GO_0032822 GO:0032821 biolink:BiologicalProcess negative regulation of natural killer cell proliferation involved in immune response Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response. go-plus.json negative regulation of natural killer cell proliferation during immune response|down-regulation of natural killer cell proliferation during immune response|negative regulation of NK cell proliferation during immune response|downregulation of natural killer cell proliferation during immune response|inhibition of natural killer cell proliferation during immune response|down regulation of natural killer cell proliferation during immune response http://purl.obolibrary.org/obo/GO_0032821 GO:0032820 biolink:BiologicalProcess regulation of natural killer cell proliferation involved in immune response Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response. go-plus.json regulation of natural killer cell proliferation during immune response|regulation of NK cell proliferation during immune response http://purl.obolibrary.org/obo/GO_0032820 GO:0032829 biolink:BiologicalProcess regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. go-plus.json regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0032829 GO:0032828 biolink:BiologicalProcess positive regulation of natural killer cell differentiation involved in immune response Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response. go-plus.json up-regulation of natural killer cell differentiation during immune response|positive regulation of natural killer cell differentiation during immune response|up regulation of natural killer cell differentiation during immune response|positive regulation of NK cell differentiation during immune response|positive regulation of natural killer cell development involved in immune response|upregulation of natural killer cell differentiation during immune response|stimulation of natural killer cell differentiation during immune response|activation of natural killer cell differentiation during immune response http://purl.obolibrary.org/obo/GO_0032828 CHEBI:137668 biolink:ChemicalSubstance beta-muricholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137668 chebi_ph7_3 CHEBI:137667 biolink:ChemicalSubstance 3-[beta-D-glucopyranosyl-(1->6)-beta-D-galactopyranosyl]-1,2-diacyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137667 chebi_ph7_3 CHEBI:55491 biolink:ChemicalSubstance glycerol 1-phosphodiester go-plus.json http://purl.obolibrary.org/obo/CHEBI_55491 CHEBI:55493 biolink:ChemicalSubstance 1-O-acylglycerophosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55493 CHEBI:137669 biolink:ChemicalSubstance S-[(Z)-N-hydroxy-2-phenylethanimidoyl]-L-cysteinylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137669 OBA:0000127 biolink:OntologyClass pronephric kidney size The size of a pronephros. go-plus.json size of pronephros http://purl.obolibrary.org/obo/OBA_0000127 OBA:0000129 biolink:OntologyClass rRNA stability The macromolecular stability of a rRNA. go-plus.json macromolecular stability of rRNA http://purl.obolibrary.org/obo/OBA_0000129 OBA:0000128 biolink:OntologyClass protein stability The macromolecular stability of a protein. go-plus.json macromolecular stability of protein http://purl.obolibrary.org/obo/OBA_0000128 CHEBI:137664 biolink:ChemicalSubstance allodeoxycholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137664 chebi_ph7_3 OBA:0000123 biolink:OntologyClass plasma membrane sterol distribution The spatial pattern of a sterol when measured in plasma membrane. go-plus.json plasma membrane sterol spatial pattern http://purl.obolibrary.org/obo/OBA_0000123 OBA:0000122 biolink:OntologyClass peroxisome size The size of a peroxisome. go-plus.json size of peroxisome http://purl.obolibrary.org/obo/OBA_0000122 CHEBI:137663 biolink:ChemicalSubstance allocholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137663 chebi_ph7_3 CHEBI:137662 biolink:ChemicalSubstance allodeoxycholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137662 chebi_ph7_3 CHEBI:137661 biolink:ChemicalSubstance allocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137661 chebi_ph7_3 OBA:0000124 biolink:OntologyClass post-lysosomal vacuole size The size of a post-lysosomal vacuole. go-plus.json size of post-lysosomal vacuole http://purl.obolibrary.org/obo/OBA_0000124 GO:0032816 biolink:BiologicalProcess positive regulation of natural killer cell activation Any process that activates or increases the frequency, rate or extent of natural killer cell activation. go-plus.json positive regulation of NK cell activation|upregulation of natural killer cell activation|stimulation of natural killer cell activation|up-regulation of natural killer cell activation|activation of natural killer cell activation|up regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0032816 GO:0032815 biolink:BiologicalProcess negative regulation of natural killer cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. go-plus.json downregulation of natural killer cell activation|down regulation of natural killer cell activation|inhibition of natural killer cell activation|down-regulation of natural killer cell activation|negative regulation of NK cell activation http://purl.obolibrary.org/obo/GO_0032815 GO:0032814 biolink:BiologicalProcess regulation of natural killer cell activation Any process that modulates the frequency, rate or extent of natural killer cell activation. go-plus.json regulation of NK cell activation http://purl.obolibrary.org/obo/GO_0032814 OBA:0000110 biolink:OntologyClass muscle filament sliding speed The speed of a muscle filament sliding. go-plus.json speed of muscle filament sliding http://purl.obolibrary.org/obo/OBA_0000110 GO:0032813 biolink:MolecularActivity tumor necrosis factor receptor superfamily binding Binding to a member of the tumor necrosis factor receptor superfamily. go-plus.json TNF receptor superfamily binding http://purl.obolibrary.org/obo/GO_0032813 GO:0032812 biolink:BiologicalProcess positive regulation of epinephrine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine. go-plus.json upregulation of epinephrine secretion|up regulation of epinephrine secretion|activation of epinephrine secretion|stimulation of epinephrine secretion|positive regulation of adrenaline secretion|up-regulation of epinephrine secretion http://purl.obolibrary.org/obo/GO_0032812 GO:0032811 biolink:BiologicalProcess negative regulation of epinephrine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine. go-plus.json down regulation of epinephrine secretion|downregulation of epinephrine secretion|down-regulation of epinephrine secretion|negative regulation of adrenaline secretion|inhibition of epinephrine secretion http://purl.obolibrary.org/obo/GO_0032811 GO:0032810 biolink:MolecularActivity sterol response element binding Binding to a sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism. go-plus.json SRE binding http://purl.obolibrary.org/obo/GO_0032810 GO:0032819 biolink:BiologicalProcess positive regulation of natural killer cell proliferation Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. go-plus.json up-regulation of natural killer cell proliferation|upregulation of natural killer cell proliferation|positive regulation of NK cell proliferation|up regulation of natural killer cell proliferation|activation of natural killer cell proliferation|stimulation of natural killer cell proliferation http://purl.obolibrary.org/obo/GO_0032819 GO:0032818 biolink:BiologicalProcess negative regulation of natural killer cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation. go-plus.json down-regulation of natural killer cell proliferation|inhibition of natural killer cell proliferation|down regulation of natural killer cell proliferation|downregulation of natural killer cell proliferation|negative regulation of NK cell proliferation http://purl.obolibrary.org/obo/GO_0032818 GO:0032817 biolink:BiologicalProcess regulation of natural killer cell proliferation Any process that modulates the frequency, rate or extent of natural killer cell proliferation. go-plus.json regulation of NK cell proliferation http://purl.obolibrary.org/obo/GO_0032817 CHEBI:137639 biolink:ChemicalSubstance long-chain (3S)-hydroxy fatty acyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137639 OBA:0000119 biolink:OntologyClass nucleosome density The amount of a nucleosome. go-plus.json amount of nucleosome http://purl.obolibrary.org/obo/OBA_0000119 OBA:0000116 biolink:OntologyClass neurotransmitter levels The amount of a neurotransmitter. go-plus.json amount of neurotransmitter http://purl.obolibrary.org/obo/OBA_0000116 OBA:0000117 biolink:OntologyClass nuclear size The size of a nucleus. go-plus.json size of nucleus http://purl.obolibrary.org/obo/OBA_0000117 OBA:0000112 biolink:OntologyClass myofibril number The amount of a myofibril. go-plus.json amount of myofibril http://purl.obolibrary.org/obo/OBA_0000112 CHEBI:55485 biolink:ChemicalSubstance dermatan 6'-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55485 CHEBI:55484 biolink:ChemicalSubstance alpha-phenylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55484 OBA:0000114 biolink:OntologyClass neuronal synaptic plasticity The synaptic plasticity of a neuron. go-plus.json synaptic plasticity of neuron http://purl.obolibrary.org/obo/OBA_0000114 OBA:0000113 biolink:OntologyClass myofibril size The size of a myofibril. go-plus.json size of myofibril http://purl.obolibrary.org/obo/OBA_0000113 GO:0032805 biolink:BiologicalProcess positive regulation of low-density lipoprotein particle receptor catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors. go-plus.json positive regulation of low-density lipoprotein receptor catabolic process|up regulation of low-density lipoprotein receptor catabolic process|upregulation of low-density lipoprotein receptor catabolic process|positive regulation of low-density lipoprotein receptor catabolism|stimulation of low-density lipoprotein receptor catabolic process|up-regulation of low-density lipoprotein receptor catabolic process|activation of low-density lipoprotein receptor catabolic process|positive regulation of low-density lipoprotein receptor degradation|positive regulation of low-density lipoprotein receptor breakdown http://purl.obolibrary.org/obo/GO_0032805 GO:0032804 biolink:BiologicalProcess negative regulation of low-density lipoprotein particle receptor catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors. go-plus.json downregulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolic process|down regulation of low-density lipoprotein receptor catabolic process|inhibition of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolism|negative regulation of low-density lipoprotein receptor degradation|negative regulation of low-density lipoprotein receptor breakdown|down-regulation of low-density lipoprotein receptor catabolic process http://purl.obolibrary.org/obo/GO_0032804 GO:0032803 biolink:BiologicalProcess regulation of low-density lipoprotein particle receptor catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors. go-plus.json regulation of LDLr catabolism|regulation of low-density lipoprotein receptor breakdown|regulation of low-density lipoprotein receptor catabolic process|regulation of low-density lipoprotein receptor catabolism|regulation of LDLr catabolic process|regulation of low-density lipoprotein receptor degradation http://purl.obolibrary.org/obo/GO_0032803 GO:0032802 biolink:BiologicalProcess low-density lipoprotein particle receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json low-density lipoprotein receptor catabolic process|LDL receptor degradation|low-density lipoprotein receptor degradation|low-density lipoprotein receptor catabolism|LDL receptor breakdown|low-density lipoprotein receptor breakdown|LDL receptor catabolic process|LDL receptor catabolism http://purl.obolibrary.org/obo/GO_0032802 GO:0032801 biolink:BiologicalProcess receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json receptor breakdown|receptor catabolism|receptor degradation http://purl.obolibrary.org/obo/GO_0032801 GO:0032800 biolink:BiologicalProcess obsolete receptor biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. go-plus.json receptor anabolism|receptor biosynthesis|receptor synthesis|receptor formation http://purl.obolibrary.org/obo/GO_0032800 GO:0032809 biolink:CellularComponent neuronal cell body membrane The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites. go-plus.json neuron cell body membrane|neuronal cell soma membrane http://purl.obolibrary.org/obo/GO_0032809 GO:0032808 biolink:BiologicalProcess lacrimal gland development The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. go-plus.json http://purl.obolibrary.org/obo/GO_0032808 GO:0032807 biolink:CellularComponent DNA ligase IV complex A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p. go-plus.json DNA ligase IV-XRCC4 complex http://purl.obolibrary.org/obo/GO_0032807 GO:0032806 biolink:CellularComponent carboxy-terminal domain protein kinase complex A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5. go-plus.json CTDK complex http://purl.obolibrary.org/obo/GO_0032806 CHEBI:137643 biolink:ChemicalSubstance (22E)-3-oxochola-4,22-dien-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137643 OBA:0000105 biolink:OntologyClass mitochondrial membrane potential The membrane potential of a mitochondrial membrane. go-plus.json membrane potential of mitochondrial membrane http://purl.obolibrary.org/obo/OBA_0000105 CHEBI:55478 biolink:ChemicalSubstance beta-GlcNAc-(1->4)-MurNAc-L-Ala-gamma-D-Glu-N(6)-(beta-D-Asp)-L-Lys-(D-Ala)2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_55478 OBA:0000104 biolink:OntologyClass mitochondrial membrane permeability The permeability of a mitochondrial membrane. go-plus.json permeability of mitochondrial membrane http://purl.obolibrary.org/obo/OBA_0000104 OBA:0000107 biolink:OntologyClass multivesicular body size The size of a multivesicular body. go-plus.json size of multivesicular body http://purl.obolibrary.org/obo/OBA_0000107 OBA:0000106 biolink:OntologyClass mitochondrial rRNA stability The macromolecular stability of a rRNA when measured in mitochondrion. go-plus.json mitochondrion rRNA macromolecular stability http://purl.obolibrary.org/obo/OBA_0000106 CHEBI:55479 biolink:ChemicalSubstance cis-3-hydroxy-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_55479 OBA:0000101 biolink:OntologyClass metanephric kidney size The size of a metanephros. go-plus.json size of metanephros http://purl.obolibrary.org/obo/OBA_0000101 CHEBI:55474 biolink:ChemicalSubstance N-acyl-L-homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_55474 chebi_ph7_3 OBA:0000103 biolink:OntologyClass mitochondrial mRNA stability The macromolecular stability of a mRNA when measured in mitochondrion. go-plus.json mitochondrion mRNA macromolecular stability http://purl.obolibrary.org/obo/OBA_0000103 CHEBI:55476 biolink:ChemicalSubstance N-formyl-D-kynurenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55476 OBA:0000102 biolink:OntologyClass microvillus length The length of a microvillus. go-plus.json length of microvillus http://purl.obolibrary.org/obo/OBA_0000102 GO:0150192 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150192 OBA:0000174 biolink:OntologyClass vascular permeability The permeability of a vessel. go-plus.json permeability of vessel http://purl.obolibrary.org/obo/OBA_0000174 GO:0150191 biolink:BiologicalProcess positive regulation of interleukin-32 production Any process that activates or increases the frequency, rate or extent of interleukin-32 production. go-plus.json positive regulation of interleukin-32 biosynthetic process|positive regulation of interleukin-32 secretion http://purl.obolibrary.org/obo/GO_0150191 OBA:0000173 biolink:OntologyClass urinary volume The volume of a urine. go-plus.json volume of urine http://purl.obolibrary.org/obo/OBA_0000173 GO:0150190 biolink:BiologicalProcess negative regulation of interleukin-32 production Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production. go-plus.json negative regulation of interleukin-32 secretion|negative regulation of interleukin-32 biosynthetic process http://purl.obolibrary.org/obo/GO_0150190 OBA:0000172 biolink:OntologyClass tube size The size of a tube. go-plus.json size of tube http://purl.obolibrary.org/obo/OBA_0000172 OBA:0000171 biolink:OntologyClass tube diameter The diameter of a tube. go-plus.json diameter of tube http://purl.obolibrary.org/obo/OBA_0000171 GO:0150195 biolink:BiologicalProcess transport across blood-cerebrospinal fluid barrier The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier. go-plus.json transport across BCSFB|transport across blood/cerebrospinal fluid barrier|transport across blood-CSF barrier|transport across blood/CSF barrier http://purl.obolibrary.org/obo/GO_0150195 GO:0150194 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150194 GO:0150193 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150193 CHEBI:55467 biolink:ChemicalSubstance dalpatein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_55467 chebi_ph7_3 UBERON:0006648 biolink:AnatomicalEntity adventitia of seminal vesicle An adventitia that is part of a seminal vesicle. go-plus.json adventitia of seminal gland|seminal vesicle adventitia|tunica adventitia glandulae vesiculosae|tunica adventitia (vesicula seminalis) http://purl.obolibrary.org/obo/UBERON_0006648 UBERON:0006647 biolink:AnatomicalEntity adventitia of ductus deferens An adventitia that is part of a vas deferens. go-plus.json tunica adventitia (ductus deferens)|adventitia of vas deferens|adventitia of ductus deferens|deferent ductal adventitia|adventitia of deferent duct|tunica adventitia ductus deferentis http://purl.obolibrary.org/obo/UBERON_0006647 CHEBI:55469 biolink:ChemicalSubstance N-acetyl-2-arylethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55469 chebi_ph7_3 UBERON:0006646 biolink:AnatomicalEntity muscle layer of epididymis A muscle layer that is part of a epididymis. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006646 UBERON:0006645 biolink:AnatomicalEntity adventitia of epididymis An adventitia that is part of a epididymis. go-plus.json epididymis adventitia http://purl.obolibrary.org/obo/UBERON_0006645 CHEBI:55465 biolink:ChemicalSubstance 7-hydroxyisoflavones go-plus.json http://purl.obolibrary.org/obo/CHEBI_55465 chebi_ph7_3 UBERON:0006642 biolink:AnatomicalEntity muscle layer of oviduct A muscle layer that is part of a fallopian tube. go-plus.json muscular coat of uterine tube|muscle layer of fallopian tube|uterine tubal muscularis|muscular layer of uterine tube|muscularis of uterine tube|tunica muscularis (Tuba uterina)|tunica muscularis tubae uterinae|muscle layer of uterine tube|muscle layer of oviduct http://purl.obolibrary.org/obo/UBERON_0006642 CHEBI:55464 biolink:ChemicalSubstance 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_55464 OBA:0000164 biolink:OntologyClass velocity of shortening of skeletal muscle modulating contraction The speed of a skeletal muscle contraction. go-plus.json the velocity of shortening of skeletal muscle modulating contraction|velocity of shortening of skeletal muscle|speed of skeletal muscle contraction http://purl.obolibrary.org/obo/OBA_0000164 OBA:0000161 biolink:OntologyClass force of heart contraction The force of a heart contraction. go-plus.json the force of heart contraction|force of heart contraction http://purl.obolibrary.org/obo/OBA_0000161 OBA:0000160 biolink:OntologyClass thalamus size The size of a dorsal plus ventral thalamus. go-plus.json size of dorsal plus ventral thalamus http://purl.obolibrary.org/obo/OBA_0000160 CHEBI:137626 biolink:ChemicalSubstance EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_137626 CHEBI:55456 biolink:ChemicalSubstance delphinidin 3,3',5-tri-O-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_55456 CHEBI:55455 biolink:ChemicalSubstance delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_55455 CHEBI:55458 biolink:ChemicalSubstance 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_55458 chebi_ph7_3 OBA:0000167 biolink:OntologyClass tracheal tube length The length of a respiratory tube. go-plus.json length of respiratory tube http://purl.obolibrary.org/obo/OBA_0000167 CHEBI:3230 biolink:ChemicalSubstance butachlor go-plus.json http://purl.obolibrary.org/obo/CHEBI_3230 chebi_ph7_3 OBA:0000166 biolink:OntologyClass tracheal tube diameter The diameter of a respiratory tube. go-plus.json diameter of respiratory tube http://purl.obolibrary.org/obo/OBA_0000166 CHEBI:55451 biolink:ChemicalSubstance lipoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_55451 OBA:0000169 biolink:OntologyClass translational accuracy The functionality of a translation. go-plus.json functionality of translation|translational fidelity http://purl.obolibrary.org/obo/OBA_0000169 UBERON:0006632 biolink:AnatomicalEntity musculo-phrenic artery An artery with its origin in the lateral terminal branch of the internal thoracic artery, with distribution to the diaphragm and the intercostal muscles, and with anastomoses to the branches of the pericardiacophrenic and inferior phrenic. go-plus.json musculophrenic artery http://purl.obolibrary.org/obo/UBERON_0006632 OBA:0000168 biolink:OntologyClass tracheal tube size The size of a respiratory tube. go-plus.json size of respiratory tube http://purl.obolibrary.org/obo/OBA_0000168 GO:0150170 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150170 UBERON:0006617 biolink:AnatomicalEntity left external ear An external ear that is in the left side of a multicellular organism. go-plus.json left auricular region http://purl.obolibrary.org/obo/UBERON_0006617 GO:0150178 biolink:BiologicalProcess regulation of phosphatidylserine metabolic process Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150178 GO:0150177 biolink:BiologicalProcess negative regulation of phosphatidylethanolamine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150177 GO:0150176 biolink:BiologicalProcess positive regulation of phosphatidylethanolamine metabolic process Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150176 GO:0150175 biolink:BiologicalProcess regulation of phosphatidylethanolamine metabolic process Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150175 GO:0150174 biolink:BiologicalProcess negative regulation of phosphatidylcholine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150174 GO:0150173 biolink:BiologicalProcess positive regulation of phosphatidylcholine metabolic process Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150173 GO:0150172 biolink:BiologicalProcess regulation of phosphatidylcholine metabolic process Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150172 GO:0150171 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150171 GO:0150179 biolink:BiologicalProcess positive regulation of phosphatidylserine metabolic process Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150179 OBA:0000141 biolink:OntologyClass synaptic plasticity go-plus.json http://purl.obolibrary.org/obo/OBA_0000141 GO:0150180 biolink:BiologicalProcess negative regulation of phosphatidylserine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_0150180 OBA:0000140 biolink:OntologyClass synaptic metaplasticity go-plus.json http://purl.obolibrary.org/obo/OBA_0000140 OBA:0000143 biolink:OntologyClass systemic arterial blood pressure The pressure of a blood when measured in systemic artery. go-plus.json systemic artery blood pressure http://purl.obolibrary.org/obo/OBA_0000143 CHEBI:55438 biolink:ChemicalSubstance Ile(5)-angiotensin II (1-7) go-plus.json http://purl.obolibrary.org/obo/CHEBI_55438 CHEBI:55437 biolink:ChemicalSubstance 2-demethylmenaquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_55437 chebi_ph7_3 UBERON:0006606 biolink:AnatomicalEntity mandibular symphysis A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]. go-plus.json inter-dentary joint|symphysis mandibulae|symphysis menti|mental symphysis|inter-mandibular joint|dentary symphysis http://purl.obolibrary.org/obo/UBERON_0006606 GO:0150189 biolink:BiologicalProcess regulation of interleukin-32 production Any process that modulates the frequency, rate or extent of interleukin-32 production. go-plus.json regulation of interleukin-32 secretion|regulation of interleukin-32 biosynthetic process http://purl.obolibrary.org/obo/GO_0150189 GO:0150188 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0150188 CHEBI:137600 biolink:ChemicalSubstance 2-hydroxy-7,8-dihydropteroate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137600 chebi_ph7_3 UBERON:0006616 biolink:AnatomicalEntity right external ear An external ear that is in the right side of a multicellular organism. go-plus.json right auricular region http://purl.obolibrary.org/obo/UBERON_0006616 CHEBI:31488 biolink:ChemicalSubstance N-acylsphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_31488 chebi_ph7_3 NCBITaxon:1307775 biolink:OrganismalEntity Anserineae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1307775 CHEBI:55436 biolink:ChemicalSubstance 2-arylethylamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55436 CHEBI:55435 biolink:ChemicalSubstance beta-Asp-Arg go-plus.json http://purl.obolibrary.org/obo/CHEBI_55435 CHEBI:55430 biolink:ChemicalSubstance 1-O-hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_55430 chebi_ph7_3 CHEBI:3211 biolink:ChemicalSubstance bulbocapnine go-plus.json http://purl.obolibrary.org/obo/CHEBI_3211 GO:0042365 biolink:BiologicalProcess water-soluble vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water. go-plus.json water-soluble vitamin catabolism|water-soluble vitamin degradation|water-soluble vitamin breakdown http://purl.obolibrary.org/obo/GO_0042365 GO:0042364 biolink:BiologicalProcess water-soluble vitamin biosynthetic process The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water. go-plus.json water-soluble vitamin anabolism|water-soluble vitamin synthesis|water-soluble vitamin formation|water-soluble vitamin biosynthesis http://purl.obolibrary.org/obo/GO_0042364 GO:0042367 biolink:BiologicalProcess biotin catabolic process The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid. go-plus.json vitamin B7 catabolism|vitamin B7 catabolic process|biotin catabolism|vitamin H catabolic process|biotin degradation|vitamin H catabolism|biotin breakdown http://purl.obolibrary.org/obo/GO_0042367 GO:0042366 biolink:BiologicalProcess cobalamin catabolic process The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. go-plus.json cobalamin catabolism|vitamin B12 catabolism|cobalamin degradation|cobalamin breakdown|vitamin B12 catabolic process http://purl.obolibrary.org/obo/GO_0042366 GO:0042361 biolink:BiologicalProcess menaquinone catabolic process The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2. go-plus.json menatetrenone catabolic process|menaquinone catabolism|vitamin K2 catabolism|menaquinone degradation|multiprenylmenaquinone catabolic process|multiprenylmenaquinone catabolism|menaquinone breakdown|vitamin K2 catabolic process|menatetrenone catabolism http://purl.obolibrary.org/obo/GO_0042361 GO:0042360 biolink:BiologicalProcess vitamin E metabolic process The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. go-plus.json tocopherol metabolism|alpha-tocopherol metabolic process|alpha-tocopherol metabolism|vitamin E metabolism|tocopherol metabolic process http://purl.obolibrary.org/obo/GO_0042360 GO:0042363 biolink:BiologicalProcess fat-soluble vitamin catabolic process The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. go-plus.json fat-soluble vitamin catabolism|fat-soluble vitamin degradation|fat-soluble vitamin breakdown http://purl.obolibrary.org/obo/GO_0042363 GO:0042362 biolink:BiologicalProcess fat-soluble vitamin biosynthetic process The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. go-plus.json fat-soluble vitamin synthesis|fat-soluble vitamin formation|fat-soluble vitamin biosynthesis|fat-soluble vitamin anabolism http://purl.obolibrary.org/obo/GO_0042362 GO:0042369 biolink:BiologicalProcess vitamin D catabolic process The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json ergocalciferol biosynthetic process|ergocalciferol biosynthesis|calciferol catabolic process|vitamin D degradation|vitamin D catabolism|calciferol catabolism|vitamin D breakdown|cholecalciferol biosynthetic process|cholecalciferol biosynthesis http://purl.obolibrary.org/obo/GO_0042369 GO:0042368 biolink:BiologicalProcess vitamin D biosynthetic process The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json vitamin D anabolism|vitamin D synthesis|vitamin D formation|ergocalciferol biosynthetic process|ergocalciferol biosynthesis|vitamin D biosynthesis|calciferol biosynthesis|calciferol biosynthetic process|cholecalciferol biosynthesis|cholecalciferol biosynthetic process http://purl.obolibrary.org/obo/GO_0042368 GO:0042370 biolink:BiologicalProcess thiamine diphosphate dephosphorylation The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. go-plus.json thiamin diphosphate dephosphorylation|TPP dephosphorylation http://purl.obolibrary.org/obo/GO_0042370 GO:0042376 biolink:BiologicalProcess phylloquinone catabolic process The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants. go-plus.json vitamin K1 catabolism|phytomenadione catabolic process|phytomenadione catabolism|phylloquinone degradation|vitamin K1 catabolic process|phylloquinone breakdown|phytonadione catabolic process|phytylmenaquinone catabolic process|phytylmenaquinone catabolism|phylloquinone catabolism|phytonadione catabolism http://purl.obolibrary.org/obo/GO_0042376 GO:0042375 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042375 GO:0042378 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042378 GO:0042377 biolink:BiologicalProcess vitamin K catabolic process The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. go-plus.json vitamin K catabolism|naphthoquinone catabolic process|vitamin K degradation|naphthoquinone catabolism|vitamin K breakdown http://purl.obolibrary.org/obo/GO_0042377 GO:0042372 biolink:BiologicalProcess phylloquinone biosynthetic process The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants. MetaCyc:PWY-5027 go-plus.json vitamin K1 biosynthetic process|vitamin K1 biosynthesis|phytomenadione biosynthesis|phytomenadione biosynthetic process|phylloquinone anabolism|phylloquinone synthesis|phytylmenaquinone biosynthesis|phytylmenaquinone biosynthetic process|phylloquinone formation|phylloquinone biosynthesis|phytonadione biosynthesis|phytonadione biosynthetic process http://purl.obolibrary.org/obo/GO_0042372 GO:0042371 biolink:BiologicalProcess vitamin K biosynthetic process The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. go-plus.json vitamin K anabolism|vitamin K synthesis|naphthoquinone metabolism|vitamin K biosynthesis|vitamin K formation|naphthoquinone metabolic process http://purl.obolibrary.org/obo/GO_0042371 GO:0042374 biolink:BiologicalProcess phylloquinone metabolic process The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1. go-plus.json phylloquinone metabolism|vitamin K1 metabolic process|phytonadione metabolism|vitamin K1 metabolism|phytonadione metabolic process|phytomenadione metabolism|phytylmenaquinone metabolic process|phytomenadione metabolic process|phytylmenaquinone metabolism http://purl.obolibrary.org/obo/GO_0042374 GO:0042373 biolink:BiologicalProcess vitamin K metabolic process The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule. go-plus.json naphthoquinone metabolism|vitamin K metabolism|naphthoquinone metabolic process http://purl.obolibrary.org/obo/GO_0042373 GO:0042379 biolink:MolecularActivity chemokine receptor binding Binding to a chemokine receptor. go-plus.json chemokine receptor ligand http://purl.obolibrary.org/obo/GO_0042379 GO:0042381 biolink:BiologicalProcess hemolymph coagulation Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response. go-plus.json hemolymph clotting http://purl.obolibrary.org/obo/GO_0042381 GO:0042380 biolink:MolecularActivity hydroxymethylbutenyl pyrophosphate reductase activity Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate. go-plus.json (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) http://purl.obolibrary.org/obo/GO_0042380 GO:0042387 biolink:BiologicalProcess plasmatocyte differentiation The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response. go-plus.json http://purl.obolibrary.org/obo/GO_0042387 GO:0042386 biolink:BiologicalProcess hemocyte differentiation The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. go-plus.json arthropod blood cell differentiation http://purl.obolibrary.org/obo/GO_0042386 GO:0042389 biolink:MolecularActivity omega-3 fatty acid desaturase activity Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain. go-plus.json http://purl.obolibrary.org/obo/GO_0042389 GO:0042388 biolink:BiologicalProcess gibberellic acid mediated signaling pathway, G-alpha-dependent A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors. go-plus.json gibberellic acid mediated signalling, G-alpha-dependent http://purl.obolibrary.org/obo/GO_0042388 GO:0042383 biolink:CellularComponent sarcolemma The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers. Wikipedia:Sarcolemma go-plus.json http://purl.obolibrary.org/obo/GO_0042383 GO:0042382 biolink:CellularComponent paraspeckles Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei. Wikipedia:Paraspeckle go-plus.json http://purl.obolibrary.org/obo/GO_0042382 GO:0042385 biolink:CellularComponent myosin III complex A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain. go-plus.json http://purl.obolibrary.org/obo/GO_0042385 GO:0042384 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042384 GO:0042390 biolink:BiologicalProcess gibberellic acid mediated signaling pathway, G-alpha-independent A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors. go-plus.json gibberellic acid mediated signalling, G-alpha-independent http://purl.obolibrary.org/obo/GO_0042390 GO:0042392 biolink:MolecularActivity sphingosine-1-phosphate phosphatase activity Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate. RHEA:27518|MetaCyc:RXN3DJ-25|Reactome:R-HSA-428701|Reactome:R-HSA-428696|Reactome:R-HSA-428690 go-plus.json SPP phosphatase activity|SPPase activity|sphingosine-1-phosphate phosphohydrolase activity http://purl.obolibrary.org/obo/GO_0042392 GO:0042391 biolink:BiologicalProcess regulation of membrane potential Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0042391 OBA:0000181 biolink:OntologyClass viral protein levels go-plus.json http://purl.obolibrary.org/obo/OBA_0000181 OBA:0000183 biolink:OntologyClass blood vessel diameter The diameter of a blood vessel. go-plus.json diameter of blood vessel http://purl.obolibrary.org/obo/OBA_0000183 GO:0042398 biolink:BiologicalProcess cellular modified amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents. go-plus.json cellular modified amino acid anabolism|cellular modified amino acid synthesis|cellular modified amino acid formation|cellular amino acid derivative anabolism|cellular modified amino acid biosynthesis|cellular amino acid derivative synthesis|amino acid derivative biosynthetic process|cellular amino acid derivative formation|cellular amino acid derivative biosynthetic process|cellular amino acid derivative biosynthesis http://purl.obolibrary.org/obo/GO_0042398 GO:0042397 biolink:BiologicalProcess phosphagen catabolic process The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. go-plus.json phosphagen catabolism|phosphagen degradation|phosphagen breakdown http://purl.obolibrary.org/obo/GO_0042397 GO:0042399 biolink:BiologicalProcess ectoine metabolic process The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. go-plus.json ectoine metabolism http://purl.obolibrary.org/obo/GO_0042399 GO:0042394 biolink:BiologicalProcess obsolete ecdysis, protein-based cuticle OBSOLETE. The shedding of the old protein-based cuticular fragments during the molting cycle. Examples of this process are found in invertebrates. go-plus.json ecdysis, protein-based cuticle http://purl.obolibrary.org/obo/GO_0042394 GO:0042393 biolink:MolecularActivity histone binding Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. go-plus.json histone-specific chaperone activity http://purl.obolibrary.org/obo/GO_0042393 goslim_chembl|goslim_yeast|goslim_drosophila|goslim_generic GO:0042396 biolink:BiologicalProcess phosphagen biosynthetic process The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. go-plus.json phosphagen synthesis|phosphagen formation|phosphagen biosynthesis|phosphagen anabolism http://purl.obolibrary.org/obo/GO_0042396 GO:0042395 biolink:BiologicalProcess ecdysis, collagen and cuticulin-based cuticle The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0042395 CHEBI:3015 biolink:ChemicalSubstance benomyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_3015 chebi_ph7_3 GO:0032999 biolink:CellularComponent Fc-alpha receptor I complex A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA. go-plus.json FcaRI complex|immunoglobulin A receptor complex|IgA receptor complex http://purl.obolibrary.org/obo/GO_0032999 GO:0032998 biolink:CellularComponent Fc-epsilon receptor I complex A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE. go-plus.json FceRI complex|immunoglobulin E receptor complex|IgE receptor complex http://purl.obolibrary.org/obo/GO_0032998 GO:0032997 biolink:CellularComponent Fc receptor complex A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin. go-plus.json FcR complex|immunoglobulin receptor complex|Fc-receptor complex http://purl.obolibrary.org/obo/GO_0032997 goslim_pir GO:0032996 biolink:CellularComponent Bcl3-Bcl10 complex A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus. go-plus.json http://purl.obolibrary.org/obo/GO_0032996 CHEBI:137699 biolink:ChemicalSubstance 15,17(3)-seco-F430-17(3)-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137699 GO:0032995 biolink:BiologicalProcess regulation of fungal-type cell wall biogenesis Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin. go-plus.json regulation of chitin- and beta-glucan-containing cell wall biogenesis http://purl.obolibrary.org/obo/GO_0032995 GO:0032994 biolink:CellularComponent protein-lipid complex A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other. go-plus.json http://purl.obolibrary.org/obo/GO_0032994 GO:0032993 biolink:CellularComponent protein-DNA complex A macromolecular complex containing both protein and DNA molecules. go-plus.json DNA-protein complex http://purl.obolibrary.org/obo/GO_0032993 goslim_pir GO:0032992 biolink:CellularComponent protein-carbohydrate complex A macromolecular complex containing separate protein and carbohydrate molecules. Separate in this context means not covalently bound to each other. go-plus.json http://purl.obolibrary.org/obo/GO_0032992 GO:0032991 biolink:CellularComponent protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. go-plus.json protein-protein complex|macromolecule complex|protein containing complex|protein complex|macromolecular complex http://purl.obolibrary.org/obo/GO_0032991 goslim_agr|goslim_pir|goslim_generic|goslim_flybase_ribbon|goslim_chembl GO:0032990 biolink:BiologicalProcess cell part morphogenesis The process in which the anatomical structures of a cell part are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0032990 CHEBI:137696 biolink:ChemicalSubstance nickel-sirohydrochlorin a,c-diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_137696 NCBITaxon:235883 biolink:OrganismalEntity Manihoteae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_235883 GO:0032989 biolink:BiologicalProcess cellular component morphogenesis The process in which cellular structures, including whole cells or cell parts, are generated and organized. go-plus.json cellular structure morphogenesis http://purl.obolibrary.org/obo/GO_0032989 goslim_pir GO:0032988 biolink:BiologicalProcess ribonucleoprotein complex disassembly The disaggregation of a protein-RNA complex into its constituent components. go-plus.json protein-RNA complex disassembly|RNA-protein complex disassembly|RNP complex disassembly http://purl.obolibrary.org/obo/GO_0032988 GO:0032987 biolink:BiologicalProcess protein-lipid complex disassembly The disaggregation of a protein-lipid complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0032987 GO:0032986 biolink:BiologicalProcess protein-DNA complex disassembly The disaggregation of a protein-DNA complex into its constituent components. go-plus.json DNA-protein complex disassembly http://purl.obolibrary.org/obo/GO_0032986 GO:0032985 biolink:BiologicalProcess protein-carbohydrate complex disassembly The disaggregation of a protein-carbohydrate complex into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0032985 NCBITaxon:284812 biolink:OrganismalEntity Schizosaccharomyces pombe 972h- go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_284812 NCBITaxon:284811 biolink:OrganismalEntity Eremothecium gossypii ATCC 10895 go-plus.json Ashbya gossypii ATCC 10895 http://purl.obolibrary.org/obo/NCBITaxon_284811 GO:0032984 biolink:BiologicalProcess protein-containing complex disassembly The disaggregation of a protein-containing macromolecular complex into its constituent components. go-plus.json cellular macromolecule complex disassembly|macromolecule complex disassembly|protein complex disassembly http://purl.obolibrary.org/obo/GO_0032984 GO:0032983 biolink:CellularComponent kainate selective glutamate receptor complex An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0032983 GO:0032982 biolink:CellularComponent myosin filament A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament. go-plus.json myosin thick filament|thick filament http://purl.obolibrary.org/obo/GO_0032982 GO:0032981 biolink:BiologicalProcess mitochondrial respiratory chain complex I assembly The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. go-plus.json mitochondrial complex I assembly|mitochondrial NADH dehydrogenase complex (ubiquinone) assembly http://purl.obolibrary.org/obo/GO_0032981 GO:0032980 biolink:BiologicalProcess keratinocyte activation A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. go-plus.json http://purl.obolibrary.org/obo/GO_0032980 GO:0032979 biolink:BiologicalProcess protein insertion into mitochondrial inner membrane from matrix The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix. go-plus.json protein insertion into mitochondrial membrane from inner side|insertion of proteins into the mitochondrial membrane from the inner side|protein insertion into mitochondrial inner membrane from matrix side http://purl.obolibrary.org/obo/GO_0032979 GO:0032978 biolink:BiologicalProcess protein insertion into membrane from inner side The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side. go-plus.json insertion of proteins into membrane from the inner side http://purl.obolibrary.org/obo/GO_0032978 GO:0032977 biolink:MolecularActivity membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane. Reactome:R-HSA-1299482|Reactome:R-HSA-1268025|Reactome:R-HSA-1307803 go-plus.json http://purl.obolibrary.org/obo/GO_0032977 GO:0032976 biolink:BiologicalProcess release of matrix enzymes from mitochondria The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process. go-plus.json release of aspartate aminotransferase from mitochondria|mAST release from mitochondria http://purl.obolibrary.org/obo/GO_0032976 GO:0032975 biolink:BiologicalProcess amino acid transmembrane import into vacuole The directed movement of amino acids into the vacuole across the vacuolar membrane. go-plus.json vacuolar amino acid import http://purl.obolibrary.org/obo/GO_0032975 GO:0032974 biolink:BiologicalProcess amino acid transmembrane export from vacuole The directed movement of amino acids out of the vacuole, across the vacuolar membrane. go-plus.json amino acid efflux from vacuole|vacuolar amino acid export http://purl.obolibrary.org/obo/GO_0032974 CHEBI:137679 biolink:ChemicalSubstance ursodeoxycholoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137679 chebi_ph7_3 CHEBI:137678 biolink:ChemicalSubstance nickel-sirohydrochlorin go-plus.json http://purl.obolibrary.org/obo/CHEBI_137678 CHEBI:137677 biolink:ChemicalSubstance glycolaldehyde triphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137677 CHEBI:137676 biolink:ChemicalSubstance Cys(IAN)-Gly go-plus.json http://purl.obolibrary.org/obo/CHEBI_137676 GO:0032973 biolink:BiologicalProcess amino acid export across plasma membrane The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json amino acid transmembrane export|amino acid efflux|amino acid export http://purl.obolibrary.org/obo/GO_0032973 GO:0032972 biolink:BiologicalProcess regulation of muscle filament sliding speed Any process that modulates the velocity of muscle filament sliding. go-plus.json http://purl.obolibrary.org/obo/GO_0032972 GO:0032971 biolink:BiologicalProcess regulation of muscle filament sliding Any process that modulates the frequency, rate or extent of muscle filament sliding. go-plus.json http://purl.obolibrary.org/obo/GO_0032971 GO:0032970 biolink:BiologicalProcess regulation of actin filament-based process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. go-plus.json http://purl.obolibrary.org/obo/GO_0032970 CHEBI:137675 biolink:ChemicalSubstance thiobenzaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_137675 chebi_ph7_3 CHEBI:137674 biolink:ChemicalSubstance benzyl thiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137674 chebi_ph7_3 CHEBI:137673 biolink:ChemicalSubstance 3-sulfinatopropionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137673 chebi_ph7_3 CHEBI:137672 biolink:ChemicalSubstance S-[(E)-N-hydroxy-2-(indol-3-yl)ethanimidoyl]-L-cysteinylglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137672 GO:0032969 biolink:CellularComponent endosomal scaffold complex A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling. go-plus.json MP1-p14 scaffolding complex|endosomal adaptor complex http://purl.obolibrary.org/obo/GO_0032969 GO:0032968 biolink:BiologicalProcess positive regulation of transcription elongation from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. go-plus.json positive regulation of gene-specific transcription elongation from RNA polymerase II promoter|positive regulation of RNA elongation from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0032968 GO:0032967 biolink:BiologicalProcess positive regulation of collagen biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. go-plus.json positive regulation of collagen synthesis|positive regulation of collagen formation|positive regulation of collagen biosynthesis|positive regulation of collagen anabolism http://purl.obolibrary.org/obo/GO_0032967 GO:0032966 biolink:BiologicalProcess negative regulation of collagen biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. go-plus.json negative regulation of collagen biosynthesis|negative regulation of collagen anabolism|negative regulation of collagen synthesis|negative regulation of collagen formation http://purl.obolibrary.org/obo/GO_0032966 GO:0032965 biolink:BiologicalProcess regulation of collagen biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. go-plus.json regulation of collagen anabolism|regulation of collagen synthesis|regulation of collagen formation|regulation of collagen biosynthesis http://purl.obolibrary.org/obo/GO_0032965 GO:0032964 biolink:BiologicalProcess collagen biosynthetic process The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). go-plus.json collagen anabolism|collagen biosynthesis|collagen synthesis|collagen formation http://purl.obolibrary.org/obo/GO_0032964 GO:0032963 biolink:BiologicalProcess collagen metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). go-plus.json collagen metabolism http://purl.obolibrary.org/obo/GO_0032963 CHEBI:55393 biolink:ChemicalSubstance (S)-piperazine-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55393 CHEBI:55392 biolink:ChemicalSubstance (S)-piperazine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55392 CHEBI:137688 biolink:ChemicalSubstance (25R)-26-hydroxycholestanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137688 chebi_ph7_3 CHEBI:137687 biolink:ChemicalSubstance (24S)-hydroxycholestanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137687 chebi_ph7_3 CHEBI:55391 biolink:ChemicalSubstance (S)-piperazine-2-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_55391 CHEBI:55390 biolink:ChemicalSubstance dicarbide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_55390 GO:0032962 biolink:BiologicalProcess positive regulation of inositol trisphosphate biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate. go-plus.json positive regulation of myo-inositol trisphosphate biosynthetic process|positive regulation of myo-inositol trisphosphate biosynthesis|positive regulation of IP3 biosynthesis|positive regulation of IP3 biosynthetic process|positive regulation of inositol trisphosphate anabolism|positive regulation of inositol trisphosphate synthesis|positive regulation of inositol trisphosphate formation|positive regulation of inositol trisphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0032962 GO:0032961 biolink:BiologicalProcess negative regulation of inositol trisphosphate biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate. go-plus.json negative regulation of myo-inositol trisphosphate biosynthesis|negative regulation of myo-inositol trisphosphate biosynthetic process|negative regulation of IP3 biosynthesis|negative regulation of IP3 biosynthetic process|negative regulation of inositol trisphosphate anabolism|negative regulation of inositol trisphosphate synthesis|negative regulation of inositol trisphosphate formation|negative regulation of inositol trisphosphate biosynthesis http://purl.obolibrary.org/obo/GO_0032961 GO:0032960 biolink:BiologicalProcess regulation of inositol trisphosphate biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate. go-plus.json regulation of IP3 biosynthetic process|regulation of IP3 biosynthesis|regulation of inositol trisphosphate anabolism|regulation of inositol trisphosphate biosynthesis|regulation of myo-inositol trisphosphate biosynthesis|regulation of inositol trisphosphate synthesis|regulation of myo-inositol trisphosphate biosynthetic process|regulation of inositol trisphosphate formation http://purl.obolibrary.org/obo/GO_0032960 CHEBI:55396 biolink:ChemicalSubstance 2-dehydropyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55396 CHEBI:55399 biolink:ChemicalSubstance L-aminoacyl-L-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55399 CHEBI:137684 biolink:ChemicalSubstance Papio hamadryas metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_137684 GO:0140629 biolink:MolecularActivity small conductance calcium-activated potassium channel inhibitor activity Binds to and stops, prevents, or reduces the activity of a small conductance calcium-activated potassium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0140629 GO:0140628 biolink:MolecularActivity outward rectifier potassium channel inhibitor activity Binds to and stops, prevents, or reduces the activity of an outwardly rectifying potassium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0140628 GO:0101020 biolink:MolecularActivity estrogen 16-alpha-hydroxylase activity Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O. go-plus.json oestrogen 16-alpha-hydroxylase activity http://purl.obolibrary.org/obo/GO_0101020 GO:0101021 biolink:MolecularActivity estrogen 2-hydroxylase activity Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O. go-plus.json oestrogen 2-hydroxylase activity http://purl.obolibrary.org/obo/GO_0101021 GO:0140621 biolink:CellularComponent type I pilus A short filamentous structure on the surface of a bacterial cell distinguished from other pili by their D-mannose-sensitive agglutinatination of erythrocytes. In E. coli, type I pili consist of a short tip fibrillum made up of the adhesin protein (FimH) and two minor subunits (FimG and FimF) that is joined to the pilus rod, a homopolymer of ~1000 FimA subunits. go-plus.json type 1 pilus|type I pili|type I fimbriae http://purl.obolibrary.org/obo/GO_0140621 GO:0101024 biolink:BiologicalProcess mitotic nuclear membrane organization A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis. go-plus.json nuclear membrane organization involved in mitotic nuclear division http://purl.obolibrary.org/obo/GO_0101024 GO:0140620 biolink:MolecularActivity DNA strand exchange inhibitor activity Binds to and stops, prevents or reduces a DNA strand exchange activity. go-plus.json http://purl.obolibrary.org/obo/GO_0140620 GO:0101023 biolink:BiologicalProcess vascular endothelial cell proliferation The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0101023 GO:0140623 biolink:BiologicalProcess type I pilus assembly The assembly from its constituent parts of a type I pilus. go-plus.json type I fimbrial biogenesis|T1P assembly|type 1 pilus biogenesis|type I fimbrium assembly|type I fimbrium biogenesis|type I fimbriae assembly|type I fimbria assembly|type I fimbriae biogenesis|type I fimbrial assembly|type I fimbria biogenesis http://purl.obolibrary.org/obo/GO_0140623 GO:0101026 biolink:BiologicalProcess mitotic nuclear membrane biogenesis A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division. go-plus.json nuclear membrane biogenesis involved in mitotic nuclear division http://purl.obolibrary.org/obo/GO_0101026 GO:0140622 biolink:CellularComponent ER-to-endosome phospholipid transfer complex Lipid transfer complex that is responsible for the non-vesicular transport of phospholipids, such as phosphatidylserine, from the endoplasmic reticulum to the endosome. It resides in the endosomal (acceptor) membrane and binds to specific lipids on the donor membrane at the ER-endosome contact site. go-plus.json http://purl.obolibrary.org/obo/GO_0140622 GO:0101025 biolink:BiologicalProcess nuclear membrane biogenesis The process in which a nuclear membrane is synthesized, aggregates, and bonds together. go-plus.json http://purl.obolibrary.org/obo/GO_0101025 GO:0140625 biolink:MolecularActivity opioid growth factor receptor activity Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes. go-plus.json met-enkephalin receptor activity|metenkefalin receptor activity|methionine enkephalin receptor activity http://purl.obolibrary.org/obo/GO_0140625 GO:0101028 biolink:BiologicalProcess positive regulation of liquid surface tension Any process that activates or increases the surface tension of a liquid. go-plus.json positive regulation of surface tension of a liquid http://purl.obolibrary.org/obo/GO_0101028 GO:0101027 biolink:BiologicalProcess optical nerve axon regeneration The regrowth of axons of the optical nerve following their loss or damage. go-plus.json http://purl.obolibrary.org/obo/GO_0101027 GO:0140624 biolink:BiologicalProcess EGAD pathway The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation. go-plus.json http://purl.obolibrary.org/obo/GO_0140624 GO:0140627 biolink:BiologicalProcess ubiquitin-dependent protein catabolic process via the C-end degron rule pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. go-plus.json DesCEND http://purl.obolibrary.org/obo/GO_0140627 GO:0101029 biolink:BiologicalProcess negative regulation of liquid surface tension Any process that prevents or reduces the surface tension of a liquid. go-plus.json negative regulation of surface tension of a liquid http://purl.obolibrary.org/obo/GO_0101029 GO:0140626 biolink:BiologicalProcess opioid growth factor receptor signaling pathway The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A). Wikipedia:OGFr|Wikipedia:Opioid_receptor go-plus.json http://purl.obolibrary.org/obo/GO_0140626 CHEBI:79352 biolink:ChemicalSubstance progoitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_79352 CHEBI:79350 biolink:ChemicalSubstance xi-progoitrin go-plus.json http://purl.obolibrary.org/obo/CHEBI_79350 GO:0140618 biolink:MolecularActivity ferric-chelate reductase (NADH) activity Catalysis of the reaction: 2 Fe3+-siderophore + NAD(+) + H(+) -> 2 Fe2+-siderophore + NADH. MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN|EC:1.16.1.7|RHEA:15061 go-plus.json NADH:Fe3+ oxidoreductase activity|iron chelate reductase activity|NADH:Fe(3+) oxidoreductase activity|ferric chelate reductase activity http://purl.obolibrary.org/obo/GO_0140618 GO:0140617 biolink:BiologicalProcess transvection An epigenetic regulation of transcription by physical interaction between a cis-acting element (enhancer, silencer) of one allele on one chromosome and the promoter of the corresponding allele on the homologous chromosome. Transvection can lead to either gene activation or repression. go-plus.json http://purl.obolibrary.org/obo/GO_0140617 GO:0140619 biolink:MolecularActivity DNA strand exchange activator activity Binds to and increases a DNA strand exchange activity. go-plus.json http://purl.obolibrary.org/obo/GO_0140619 GO:0101031 biolink:CellularComponent chaperone complex A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0101031 GO:0101030 biolink:BiologicalProcess tRNA-guanine transglycosylation The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0101030 OBO:GOCHE_24869 biolink:OntologyClass substance with ionophore role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24869 3_STAR GO:0140610 biolink:MolecularActivity RNA sequestering activity The selective interaction of a protein with a specific RNA molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140610 GO:0140612 biolink:MolecularActivity DNA damage sensor activity A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signalling response. go-plus.json http://purl.obolibrary.org/obo/GO_0140612 GO:0140614 biolink:BiologicalProcess 1,8-dihydroxynaphthalene-melanin biosynthetic process The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin. go-plus.json DHN-melanin biosynthesis http://purl.obolibrary.org/obo/GO_0140614 GO:0140613 biolink:MolecularActivity P-type manganese transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(in) = ADP + H+ + Mn2+(out) + phosphate. RHEA:66820 go-plus.json http://purl.obolibrary.org/obo/GO_0140613 CHEBI:80352 biolink:ChemicalSubstance go-plus.json http://purl.obolibrary.org/obo/CHEBI_80352 GO:0140616 biolink:MolecularActivity iodotyrosine deiodinase activity Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. RHEA:32479|EC:1.21.1.1 go-plus.json monoiodotyrosine deiodinase activity|iodotyrosine deiodinase activity|iodotyrosine deiodase activity|iodide peroxidase-tyrosine iodinase activity|tyrosine iodinase activity http://purl.obolibrary.org/obo/GO_0140616 GO:0140615 biolink:CellularComponent ATP-dependent citrate lyase complex A protein complex that catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA. go-plus.json citrate lyase complex|citrate synthase complex http://purl.obolibrary.org/obo/GO_0140615 CHEBI:79364 biolink:ChemicalSubstance indolylmethylglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79364 NCBITaxon:2233839 biolink:OrganismalEntity IRL clade go-plus.json inverted repeat loss clade|inverted repeat lacking clade|temperate herbaceous clade http://purl.obolibrary.org/obo/NCBITaxon_2233839 NCBITaxon:2233838 biolink:OrganismalEntity Hologalegina go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2233838 UBERON:5102544 biolink:AnatomicalEntity individual digit of digitopodial skeleton A subdivision of the skeleton of the autopod consisting of the phalanges of a single digit plus the associated metapodial element. go-plus.json digit skeleton|digit http://purl.obolibrary.org/obo/UBERON_5102544 OBO:GOCHE_24874 biolink:OntologyClass substance with iron ionophore role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24874 3_STAR GO:0140643 biolink:MolecularActivity hydroxymethylglutaryl-CoA reductase (NADH) activity Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) <=> 3-hydroxy-3-methylglutaryl-CoA + 2 NADH. KEGG_REACTION:R02081|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN|EC:1.1.1.88|RHEA:14833 go-plus.json beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity|HMG-CoA reductase activity|beta-hydroxy-beta-methylglutaryl CoA-reductase activity|hydroxymethylglutaryl coenzyme A reductase activity|3-hydroxy-3-methylglutaryl coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_0140643 GO:0140642 biolink:BiologicalProcess meiotic spindle formation (spindle phase two) The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase. go-plus.json http://purl.obolibrary.org/obo/GO_0140642 GO:0140645 biolink:BiologicalProcess neutrophic extracellular trap formation The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens. http://purl.obolibrary.org/obo/TXPO_0002149 go-plus.json NET formation http://purl.obolibrary.org/obo/GO_0140645 GO:0042301 biolink:MolecularActivity phosphate ion binding Binding to a phosphate ion. go-plus.json http://purl.obolibrary.org/obo/GO_0042301 GO:0042300 biolink:MolecularActivity beta-amyrin synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin. MetaCyc:RXN-7570|EC:5.4.99.- go-plus.json oxidosqualene:beta-amyrin cyclase activity http://purl.obolibrary.org/obo/GO_0042300 GO:0140644 biolink:CellularComponent neutrophil extracellular trap Extracellular microbicidal structure composed of nuclear chromatin, histones and granular antimicrobial proteins. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms. go-plus.json NET http://purl.obolibrary.org/obo/GO_0140644 GO:0140647 biolink:BiologicalProcess P450-containing electron transport chain A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways. Wikipedia:P450-containing_systems go-plus.json P450-containing system http://purl.obolibrary.org/obo/GO_0140647 GO:0140646 biolink:BiologicalProcess negative regulation of pre-B cell receptor expression Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells. go-plus.json http://purl.obolibrary.org/obo/GO_0140646 GO:0140649 biolink:BiologicalProcess cell-to-cell migration by invasive hypha The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction. go-plus.json invasive growth|plant tissue colonization|host tissue colonization|invasive hyphae formation http://purl.obolibrary.org/obo/GO_0140649 GO:0140648 biolink:BiologicalProcess positive regulation of cell cycle switching, mitotic to meiotic cell cycle Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division. go-plus.json http://purl.obolibrary.org/obo/GO_0140648 GO:0042307 biolink:BiologicalProcess positive regulation of protein import into nucleus Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. go-plus.json up regulation of protein import into nucleus|activation of protein import into nucleus|positive regulation of protein-nucleus import|stimulation of protein import into nucleus|positive regulation of protein import into cell nucleus|up-regulation of protein import into nucleus|positive regulation of protein transport from cytoplasm to nucleus|upregulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_0042307 GO:0042306 biolink:BiologicalProcess regulation of protein import into nucleus Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. go-plus.json regulation of protein-nucleus import|regulation of protein transport from cytoplasm to nucleus|regulation of protein import into cell nucleus http://purl.obolibrary.org/obo/GO_0042306 GO:0042309 biolink:BiologicalProcess homoiothermy Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment. go-plus.json ice nucleation activity|antifreeze activity|ice nucleation inhibitor activity http://purl.obolibrary.org/obo/GO_0042309 GO:0042308 biolink:BiologicalProcess negative regulation of protein import into nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. go-plus.json negative regulation of protein import into cell nucleus|down-regulation of protein import into nucleus|inhibition of protein import into nucleus|negative regulation of protein transport from cytoplasm to nucleus|down regulation of protein import into nucleus|downregulation of protein import into nucleus|negative regulation of protein-nucleus import http://purl.obolibrary.org/obo/GO_0042308 GO:0042303 biolink:BiologicalProcess molting cycle The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc. go-plus.json http://purl.obolibrary.org/obo/GO_0042303 goslim_pir|goslim_drosophila GO:0042302 biolink:MolecularActivity structural constituent of cuticle The action of a molecule that contributes to the structural integrity of a cuticle. go-plus.json http://purl.obolibrary.org/obo/GO_0042302 goslim_drosophila GO:0140641 biolink:BiologicalProcess mitotic spindle formation (spindle phase two) The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase. go-plus.json metaphase spindle stability|metaphase spindle stabilization http://purl.obolibrary.org/obo/GO_0140641 GO:0042305 biolink:BiologicalProcess specification of segmental identity, mandibular segment The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0042305 GO:0042304 biolink:BiologicalProcess regulation of fatty acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. go-plus.json regulation of fatty acid anabolism|regulation of fatty acid synthesis|regulation of fatty acid formation|regulation of fatty acid biosynthesis http://purl.obolibrary.org/obo/GO_0042304 GO:0140640 biolink:MolecularActivity catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0140640 GO:0140639 biolink:BiologicalProcess positive regulation of pyroptosis Any process that increases the frequency, rate or extent of pyroptosis. go-plus.json http://purl.obolibrary.org/obo/GO_0140639 NCBITaxon:235880 biolink:OrganismalEntity Acalypheae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_235880 GO:0042310 biolink:BiologicalProcess vasoconstriction A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure. Wikipedia:Vasoconstriction go-plus.json negative regulation of blood vessel size http://purl.obolibrary.org/obo/GO_0042310 GO:0140632 biolink:BiologicalProcess inflammasome complex assembly The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140632 GO:0140631 biolink:MolecularActivity aldehyde dehydrogenase (NAD+) inhibitor activity Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+). go-plus.json http://purl.obolibrary.org/obo/GO_0140631 GO:0042312 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042312 GO:0140634 biolink:CellularComponent CARD8 inflammasome complex An inflammasome complex that consists of CARD8 and CASP1. go-plus.json http://purl.obolibrary.org/obo/GO_0140634 GO:0042311 biolink:BiologicalProcess vasodilation An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure. Wikipedia:Vasodilation go-plus.json vasodilatation|positive regulation of blood vessel size http://purl.obolibrary.org/obo/GO_0042311 GO:0140633 biolink:BiologicalProcess CARD8 inflammasome complex assembly The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex. go-plus.json http://purl.obolibrary.org/obo/GO_0140633 GO:0140636 biolink:BiologicalProcess copper import into the mitochondrion The process in which copper is transported from the cytosol into the mitochondrial matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0140636 GO:0140635 biolink:BiologicalProcess neutrophil dispersal The movement of a neutrophil away from the site of wound or infection following its initial migration to the site. go-plus.json http://purl.obolibrary.org/obo/GO_0140635 GO:0140638 biolink:CellularComponent small ribosomal subunit processing complex A small heterodimeric protein complex that is required during early maturation of nascent 40S ribosomal subunits. The complex has endonuclease activity, it interacts with the small ribosomal subunit pre-rRNA and cleave it it to produce the mature 18S (or small ribosomal subunit) rRNA. In S. cerevisiae it is composed of Rcl1p and Bms1p. go-plus.json small ribosomal subunit maturation complex http://purl.obolibrary.org/obo/GO_0140638 GO:0042318 biolink:BiologicalProcess penicillin biosynthetic process The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json penicillin anabolism|penicillin biosynthesis|penicillin synthesis|penicillin formation http://purl.obolibrary.org/obo/GO_0042318 GO:0042317 biolink:BiologicalProcess penicillin catabolic process The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. go-plus.json penicillin degradation|penicillin breakdown|penicillin catabolism http://purl.obolibrary.org/obo/GO_0042317 CHEBI:79380 biolink:ChemicalSubstance (2E,4Z)-2-hydroxy-7-methyl-6-oxo-2,4-octadienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79380 chebi_ph7_3 GO:0042319 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042319 GO:0042314 biolink:MolecularActivity bacteriochlorophyll binding Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants. go-plus.json http://purl.obolibrary.org/obo/GO_0042314 GO:0042313 biolink:BiologicalProcess protein kinase C deactivation Any process resulting in the inhibition or termination of the activity of protein kinase C. go-plus.json PKC deactivation http://purl.obolibrary.org/obo/GO_0042313 GO:0140630 biolink:MolecularActivity all-trans-phytoene synthase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate -> all-trans-phytoene + 2 diphosphate. go-plus.json phytoene synthase activity http://purl.obolibrary.org/obo/GO_0140630 GO:0042316 biolink:BiologicalProcess penicillin metabolic process The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus. go-plus.json penicillin metabolism http://purl.obolibrary.org/obo/GO_0042316 GO:0042315 biolink:MolecularActivity obsolete cytosol nonspecific dipeptidase activity OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids. go-plus.json iminodipeptidase activity|glycyl-glycine dipeptidase activity|glycylleucine peptidase activity|L-prolylglycine dipeptidase activity|glycylleucine dipeptide hydrolase activity|diglycinase activity|Gly-Leu hydrolase activity|glycyl-leucine dipeptidase activity|N2-beta-alanylarginine dipeptidase activity|N(2)-beta-alanylarginine dipeptidase activity|prolyl dipeptidase activity|cytosol nonspecific dipeptidase activity|glycyl-L-leucine hydrolase activity|prolinase activity|human cytosolic non-specific dipeptidase activity|peptidase A activity|glycyl-L-leucine dipeptidase activity|Pro-X dipeptidase activity|glycyl-L-leucine peptidase activity|non-specific dipeptidase activity|L-amino-acyl-L-amino-acid hydrolase activity|cytosol non-specific dipeptidase activity|glycylleucine hydrolase activity|prolylglycine dipeptidase activity http://purl.obolibrary.org/obo/GO_0042315 CHEBI:79383 biolink:ChemicalSubstance 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79383 CHEBI:3095 biolink:ChemicalSubstance biguanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_3095 CHEBI:79389 biolink:ChemicalSubstance monovalent inorganic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_79389 CHEBI:79388 biolink:ChemicalSubstance divalent inorganic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_79388 CHEBI:79387 biolink:ChemicalSubstance trivalent inorganic anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_79387 NCBITaxon:2233855 biolink:OrganismalEntity indigoferoid/millettioid clade go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_2233855 CHEBI:3098 biolink:ChemicalSubstance bile acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_3098 GO:0042321 biolink:BiologicalProcess negative regulation of circadian sleep/wake cycle, sleep Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. go-plus.json down regulation of circadian sleep/wake cycle, sleep|downregulation of circadian sleep/wake cycle, sleep|down-regulation of circadian sleep/wake cycle, sleep|negative regulation of sleep|inhibition of circadian sleep/wake cycle, sleep http://purl.obolibrary.org/obo/GO_0042321 GO:0042320 biolink:BiologicalProcess regulation of circadian sleep/wake cycle, REM sleep Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep. go-plus.json regulation of REM sleep http://purl.obolibrary.org/obo/GO_0042320 GO:0042323 biolink:BiologicalProcess negative regulation of circadian sleep/wake cycle, non-REM sleep Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep. go-plus.json negative regulation of non-REM sleep|inhibition of circadian sleep/wake cycle, non-REM sleep|down regulation of circadian sleep/wake cycle, non-REM sleep|downregulation of circadian sleep/wake cycle, non-REM sleep|down-regulation of circadian sleep/wake cycle, non-REM sleep http://purl.obolibrary.org/obo/GO_0042323 GO:0042322 biolink:BiologicalProcess negative regulation of circadian sleep/wake cycle, REM sleep Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep. go-plus.json inhibition of circadian sleep/wake cycle, REM sleep|negative regulation of REM sleep|down regulation of circadian sleep/wake cycle, REM sleep|downregulation of circadian sleep/wake cycle, REM sleep|down-regulation of circadian sleep/wake cycle, REM sleep http://purl.obolibrary.org/obo/GO_0042322 GO:0042329 biolink:MolecularActivity structural constituent of collagen and cuticulin-based cuticle The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans. go-plus.json structural constituent of cuticle http://purl.obolibrary.org/obo/GO_0042329 CHEBI:79392 biolink:ChemicalSubstance EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_79392 GO:0042328 biolink:MolecularActivity heparan sulfate N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate. go-plus.json heparan sulphate N-acetylglucosaminyltransferase activity|heparin N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0042328 GO:0042325 biolink:BiologicalProcess regulation of phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0042325 GO:0042324 biolink:MolecularActivity hypocretin receptor binding Binding to a hypocretin receptor. go-plus.json orexin receptor ligand|hypocretin receptor ligand|orexin receptor binding http://purl.obolibrary.org/obo/GO_0042324 GO:0042327 biolink:BiologicalProcess positive regulation of phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. go-plus.json up regulation of phosphorylation|activation of phosphorylation|stimulation of phosphorylation|up-regulation of phosphorylation|upregulation of phosphorylation http://purl.obolibrary.org/obo/GO_0042327 GO:0042326 biolink:BiologicalProcess negative regulation of phosphorylation Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. go-plus.json down-regulation of phosphorylation|inhibition of phosphorylation|down regulation of phosphorylation|downregulation of phosphorylation http://purl.obolibrary.org/obo/GO_0042326 CHEBI:79394 biolink:ChemicalSubstance indolmycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_79394 PR:000016052 biolink:Protein antigen peptide transporter 2 A protein that is a translation product of the human TAP2 gene or a 1:1 ortholog thereof. go-plus.json histocompatibility antigen modifier 2|Ham-2|Y1|peptide transporter involved in antigen processing 2|really interesting new gene 11 protein|TAP2|ABCB3|APT2|RING11|PSF2|peptide transporter PSF2|PSF-2|peptide transporter TAP2|peptide supply factor 2|ATP-binding cassette sub-family B member 3|Ham2 http://purl.obolibrary.org/obo/PR_000016052 PR:000016051 biolink:Protein antigen peptide transporter 1 A protein that is a translation product of the human TAP1 gene or a 1:1 ortholog thereof. go-plus.json Ham1|histocompatibility antigen modifier 1|Y3|Ham-1|peptide transporter involved in antigen processing 1|TAP1|ABCB2|APT1|PSF1|really interesting new gene 4 protein|peptide transporter TAP1|PSF-1|peptide transporter PSF1|ATP-binding cassette sub-family B member 2|peptide supply factor 1|RING4 http://purl.obolibrary.org/obo/PR_000016051 PR:000016053 biolink:Protein tapasin A protein that is a translation product of the human TAPBP gene or a 1:1 ortholog thereof. go-plus.json NGS-17|TAPA|TPSN|TAP-associated protein|TPN|TAPBP|TAP-binding protein|NGS17 http://purl.obolibrary.org/obo/PR_000016053 GO:0042332 biolink:BiologicalProcess gravitaxis The directed movement of a motile cell or organism in response to gravity. go-plus.json gravitactic behaviour|taxis in response to gravitational stimulus|taxis in response to gravity|gravitactic behavior|geotactic behavior|geotactic behaviour|geotaxis http://purl.obolibrary.org/obo/GO_0042332 GO:0042331 biolink:BiologicalProcess phototaxis The directed movement of a motile cell or organism in response to light. Wikipedia:Phototaxis go-plus.json taxis in response to light|phototactic behavior|phototactic behaviour http://purl.obolibrary.org/obo/GO_0042331 GO:0042334 biolink:BiologicalProcess taxis to electron acceptor The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate. go-plus.json taxis in response to electron acceptor http://purl.obolibrary.org/obo/GO_0042334 GO:0042333 biolink:BiologicalProcess chemotaxis to oxidizable substrate The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose. go-plus.json taxis in response to oxidizable substrate http://purl.obolibrary.org/obo/GO_0042333 GO:0042330 biolink:BiologicalProcess taxis The directed movement of a motile cell or organism in response to an external stimulus. Wikipedia:Taxis go-plus.json directed movement in response to stimulus http://purl.obolibrary.org/obo/GO_0042330 GO:0042339 biolink:BiologicalProcess keratan sulfate metabolic process The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. go-plus.json keratan sulphate metabolic process|keratan sulfate metabolism|keratan sulphate metabolism http://purl.obolibrary.org/obo/GO_0042339 GO:0042336 biolink:BiologicalProcess obsolete cuticle development involved in protein-based cuticle molting cycle OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. Examples of this process are found in invertebrate species. go-plus.json cuticle anabolism during molting|cuticle biosynthetic process during molting|cuticle development involved in protein-based cuticle molting cycle|cuticle formation during molting|cuticle synthesis during molting http://purl.obolibrary.org/obo/GO_0042336 GO:0042335 biolink:BiologicalProcess cuticle development The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss. go-plus.json cuticle biosynthesis|cuticle biosynthetic process|cuticle anabolism|cuticle synthesis|cuticle formation http://purl.obolibrary.org/obo/GO_0042335 goslim_drosophila GO:0042338 biolink:BiologicalProcess cuticle development involved in collagen and cuticulin-based cuticle molting cycle Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans. go-plus.json cuticle anabolism during molting|collagen and cuticulin-based cuticle development during molting|cuticle biosynthetic process during molting|cuticle formation during molting|cuticle synthesis during molting http://purl.obolibrary.org/obo/GO_0042338 GO:0042337 biolink:BiologicalProcess cuticle development involved in chitin-based cuticle molting cycle The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster. go-plus.json cuticle anabolism during molting|cuticle biosynthetic process during molting|chitin-based cuticle development during molting|cuticle formation during molting|cuticle synthesis during molting http://purl.obolibrary.org/obo/GO_0042337 GO:0140609 biolink:BiologicalProcess phycocyanobilin biosynthetic process The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA). go-plus.json phycocyanobilin biosynthesis http://purl.obolibrary.org/obo/GO_0140609 GO:0140608 biolink:MolecularActivity cysteine-type endopeptidase activator activity Binds to and increases the activity of a cysteine-type endopeptidase. go-plus.json caspase activator activator activity http://purl.obolibrary.org/obo/GO_0140608 GO:0101002 biolink:CellularComponent ficolin-1-rich granule Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry. go-plus.json ficolin-1 rich granule|ficolin granule http://purl.obolibrary.org/obo/GO_0101002 GO:0042343 biolink:BiologicalProcess indole glucosinolate metabolic process The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan. go-plus.json indole glucosinolate metabolism http://purl.obolibrary.org/obo/GO_0042343 GO:0042342 biolink:BiologicalProcess cyanogenic glycoside catabolic process The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits. go-plus.json cyanogenic glycoside degradation|cyanogenic glycoside catabolism|cyanogenic glycoside breakdown http://purl.obolibrary.org/obo/GO_0042342 GO:0101004 biolink:CellularComponent cytolytic granule membrane The lipid bilayer surrounding the cytolytic granule. go-plus.json http://purl.obolibrary.org/obo/GO_0101004 GO:0042345 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042345 GO:0042344 biolink:BiologicalProcess indole glucosinolate catabolic process The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. go-plus.json indole glucosinolate catabolism|indole glucosinolate degradation|indole glucosinolate breakdown http://purl.obolibrary.org/obo/GO_0042344 GO:0101003 biolink:CellularComponent ficolin-1-rich granule membrane The lipid bilayer surrounding a ficolin-1-rich granule. go-plus.json http://purl.obolibrary.org/obo/GO_0101003 GO:0101006 biolink:MolecularActivity protein histidine phosphatase activity Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate. RHEA:47964|EC:3.9.1.3 go-plus.json phosphohistidine phosphatase activity http://purl.obolibrary.org/obo/GO_0101006 GO:0140603 biolink:MolecularActivity obsolete ATP hydrolysis activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. go-plus.json http://purl.obolibrary.org/obo/GO_0140603 GO:0101005 biolink:MolecularActivity deubiquitinase activity Catalysis of the hydrolysis of ubiquitin from proteins. Reactome:R-HSA-9674127 go-plus.json deubiquitinase activity|ubiquitinyl hydrolase activity http://purl.obolibrary.org/obo/GO_0101005 GO:0140602 biolink:CellularComponent nucleolar ring Ring-like structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress. go-plus.json NuRs http://purl.obolibrary.org/obo/GO_0140602 GO:0101008 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to increased salt OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0101008 GO:0140605 biolink:MolecularActivity proton motive force-driven motor activity A motor activity driven by an electrochemical proton gradient (proton-motive force). PMF-driven motors are used by bacterial flagella. go-plus.json proton motive force-driven motor activity http://purl.obolibrary.org/obo/GO_0140605 GO:0042341 biolink:BiologicalProcess cyanogenic glycoside metabolic process The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits. go-plus.json cyanogenic glycoside metabolism http://purl.obolibrary.org/obo/GO_0042341 GO:0101007 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter in response to salt stress OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0101007 GO:0140604 biolink:BiologicalProcess mycofactocin biosynthetic process The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA. go-plus.json http://purl.obolibrary.org/obo/GO_0140604 GO:0042340 biolink:BiologicalProcess keratan sulfate catabolic process The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. go-plus.json keratan sulfate catabolism|keratan sulphate catabolism|keratan sulphate catabolic process|keratan sulfate degradation|keratan sulfate breakdown http://purl.obolibrary.org/obo/GO_0042340 GO:0042347 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042347 GO:0042346 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042346 GO:0042349 biolink:MolecularActivity guiding stereospecific synthesis activity The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis. go-plus.json dirigent protein http://purl.obolibrary.org/obo/GO_0042349 GO:0042348 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042348 GO:0101011 biolink:MolecularActivity inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity Catalysis of the reaction: myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = myo-inositol hexakisphosphate + phosphate. go-plus.json inositol 1-pyrophosphate 2,3,4,5,6-pentakisphosphate 1-pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0101011 GO:0101010 biolink:BiologicalProcess pulmonary blood vessel remodeling The reorganization or renovation of existing pulmonary blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0101010 GO:0042354 biolink:BiologicalProcess L-fucose metabolic process The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants. go-plus.json L-fucose metabolism http://purl.obolibrary.org/obo/GO_0042354 GO:0101013 biolink:MolecularActivity mechanosensitive voltage-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json mechanically-modulated voltage-gated sodium channel activity http://purl.obolibrary.org/obo/GO_0101013 GO:0042353 biolink:BiologicalProcess fucose biosynthetic process The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose). go-plus.json fucose anabolism|fucose synthesis|fucose biosynthesis|fucose formation http://purl.obolibrary.org/obo/GO_0042353 GO:0101012 biolink:MolecularActivity inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity Catalysis of the reaction: myo-inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate + H2O = myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate. go-plus.json inositol 1,5-bispyrophosphate 2,3,4,6-tetrakisphosphate 1-pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0101012 GO:0042356 biolink:MolecularActivity GDP-4-dehydro-D-rhamnose reductase activity Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed. EC:1.1.1.187|MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN go-plus.json GDP-4-keto-D-rhamnose reductase activity|guanosine diphosphate-4-keto-D-rhamnose reductase activity|GDP-4-keto-6-deoxy-D-mannose reductase activity|GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity http://purl.obolibrary.org/obo/GO_0042356 GO:0101014 biolink:MolecularActivity [isocitrate dehydrogenase (NADP+)] phosphatase activity Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate. MetaCyc:ICITDEHASE-KIN-PHOSPHA go-plus.json isocitrate dehydrogenase kinase/phosphatase activity http://purl.obolibrary.org/obo/GO_0101014 GO:0042355 biolink:BiologicalProcess L-fucose catabolic process The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose). go-plus.json L-fucose degradation|L-fucose breakdown|L-fucose catabolism http://purl.obolibrary.org/obo/GO_0042355 GO:0042350 biolink:BiologicalProcess GDP-L-fucose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-L-fucose synthesis|GDP-L-fucose formation|GDP-L-fucose biosynthesis|GDP-L-fucose anabolism http://purl.obolibrary.org/obo/GO_0042350 GO:0101017 biolink:BiologicalProcess regulation of mitotic DNA replication initiation from late origin Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication. go-plus.json regulation of late replication origin firing http://purl.obolibrary.org/obo/GO_0101017 GO:0101016 biolink:MolecularActivity FMN-binding domain binding Binding to the FMN-binding domain of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0101016 GO:0042352 biolink:BiologicalProcess GDP-L-fucose salvage The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30). MetaCyc:PWY-6 go-plus.json GDP-L-fucose biosynthetic process, salvage pathway|GDP-L-fucose biosynthesis, salvage pathway http://purl.obolibrary.org/obo/GO_0042352 GO:0101019 biolink:CellularComponent nucleolar exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. go-plus.json http://purl.obolibrary.org/obo/GO_0101019 GO:0042351 biolink:BiologicalProcess 'de novo' GDP-L-fucose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271). MetaCyc:PWY-66 go-plus.json 'de novo' GDP-L-fucose biosynthesis|GDP-L-fucose biosynthetic process, de novo pathway|'de novo' GDP-L-fucose anabolism|GDP-L-fucose biosynthesis, de novo pathway|'de novo' GDP-L-fucose synthesis|'de novo' GDP-L-fucose formation http://purl.obolibrary.org/obo/GO_0042351 GO:0101018 biolink:BiologicalProcess negative regulation of mitotic DNA replication initiation from late origin Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication. go-plus.json negative regulation of late replication origin firing http://purl.obolibrary.org/obo/GO_0101018 GO:0042358 biolink:BiologicalProcess thiamine diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. go-plus.json thiamin diphosphate breakdown|thiamin diphosphate catabolic process|thiamin pyrophosphate catabolic process|TPP catabolism|thiamine pyrophosphate catabolism|thiamine diphosphate catabolism|thiamine pyrophosphate catabolic process|thiamin pyrophosphate catabolism|TPP catabolic process|thiamin diphosphate catabolism|thiamin diphosphate degradation http://purl.obolibrary.org/obo/GO_0042358 GO:0042357 biolink:BiologicalProcess thiamine diphosphate metabolic process The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. go-plus.json thiamine pyrophosphate metabolic process|TPP metabolic process|TPP metabolism|thiamine pyrophosphate metabolism|thiamine diphosphate metabolism|thiamin pyrophosphate metabolism|thiamin diphosphate metabolism|thiamin diphosphate metabolic process|thiamin pyrophosphate metabolic process http://purl.obolibrary.org/obo/GO_0042357 GO:0042359 biolink:BiologicalProcess vitamin D metabolic process The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). go-plus.json ergocalciferol metabolism|ergocalciferol metabolic process|vitamin D metabolism|calciferol metabolism|cholecalciferol metabolism|cholecalciferol metabolic process|calciferol metabolic process http://purl.obolibrary.org/obo/GO_0042359 OBO:GOCHE_24852 biolink:OntologyClass substance with insecticide role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24852 3_STAR GO:0150035 biolink:BiologicalProcess regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0150035 goslim_synapse GO:0150034 biolink:CellularComponent distal axon That part of an axon close to and including the growth cone or the axon terminus. go-plus.json distal part of the axon|distal part of axon http://purl.obolibrary.org/obo/GO_0150034 GO:0150033 biolink:BiologicalProcess negative regulation of protein localization to lysosome Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0150033 GO:0150032 biolink:BiologicalProcess positive regulation of protein localization to lysosome Any process that activates or increases the frequency, rate or extent of protein localization to lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0150032 GO:0150031 biolink:BiologicalProcess regulation of protein localization to lysosome Any process that modulates the frequency, rate or extent of protein localization to lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0150031 GO:0150038 biolink:BiologicalProcess postsynaptic dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels. go-plus.json http://purl.obolibrary.org/obo/GO_0150038 goslim_synapse GO:0150037 biolink:BiologicalProcess regulation of calcium-dependent activation of synaptic vesicle fusion Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0150037 goslim_synapse GO:0150036 biolink:BiologicalProcess regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0150036 goslim_synapse CHEBI:31334 biolink:ChemicalSubstance (E)-caffeyl alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_31334 chebi_ph7_3 GO:0140698 biolink:BiologicalProcess attachment of telomeric heterochromatin to nuclear envelope The process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation. go-plus.json attachment of telomeres to nuclear envelope|attachment of telomeric chromatin to nuclear envelope|heterochromatin organization http://purl.obolibrary.org/obo/GO_0140698 GO:0150045 biolink:BiologicalProcess regulation of synaptic signaling by nitric oxide Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide. go-plus.json http://purl.obolibrary.org/obo/GO_0150045 goslim_synapse GO:0150044 biolink:BiologicalProcess regulation of postsynaptic dense core vesicle exocytosis Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0150044 goslim_synapse GO:0150043 biolink:MolecularActivity structural constituent of synapse-associated extracellular matrix The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft. go-plus.json structural constituent of extra-synaptic extracellular matrix|synapse-associated extracellular matrix structural constituent|extra-synaptic extracellular matrix structural constituent http://purl.obolibrary.org/obo/GO_0150043 goslim_synapse GO:0140699 biolink:MolecularActivity cyclic GMP-AMP synthase activity Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP. go-plus.json cyclic-GMP-AMP synthase activity http://purl.obolibrary.org/obo/GO_0140699 gocheck_do_not_annotate CHEBI:137706 biolink:ChemicalSubstance 17-epiestriol 16-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137706 GO:0140690 biolink:CellularComponent dihydropyrimidine dehydrogenase (NAD+) complex A heteromultimeric complex capable of dihydropyrimidine dehydrogenase (NAD+); in E. coli, composed of PreA and PreT. MetaCyc:CPLX0-7788 go-plus.json http://purl.obolibrary.org/obo/GO_0140690 CHEBI:137701 biolink:ChemicalSubstance 17-epiestriol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137701 UBERON:0006794 biolink:AnatomicalEntity visual processing part of nervous system go-plus.json optic lobe http://purl.obolibrary.org/obo/UBERON_0006794 CHEBI:137700 biolink:ChemicalSubstance 3-carboxy-3-hydroxypropanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137700 GO:0140692 biolink:MolecularActivity very long-chain fatty acid omega-hydroxylase activity Catalysis of the reaction: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase]. go-plus.json http://purl.obolibrary.org/obo/GO_0140692 UBERON:0006793 biolink:AnatomicalEntity deep layer of superior colliculus The innermost layer of the superior colliculus. go-plus.json superior colliculus, deep layer http://purl.obolibrary.org/obo/UBERON_0006793 UBERON:0006792 biolink:AnatomicalEntity intermediate layer of superior colliculus A layer of superior colliculus that lies between the superficial layer and the deep layer. go-plus.json central zone|superior colliculus, intermediate layer|superior colliculus, central layer|central zone of the optic tectum http://purl.obolibrary.org/obo/UBERON_0006792 GO:0140691 biolink:MolecularActivity RNA folding chaperone Binding to an RNA or an RNA-containing complex to assist the folding process. go-plus.json http://purl.obolibrary.org/obo/GO_0140691 UBERON:0006791 biolink:AnatomicalEntity superficial layer of superior colliculus The outermost layer of the superior colliculus. go-plus.json superficial grey and white zones|superior colliculus, superficial layer|superficial gray and white zone|superficial grey and white zone http://purl.obolibrary.org/obo/UBERON_0006791 GO:0140694 biolink:BiologicalProcess non-membrane-bounded organelle assembly The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. go-plus.json non-membrane-enclosed organelle assembly|non-membrane-bounded organelle formation|non-membrane-bounded organelle assembly|non-membrane-enclosed organelle formation http://purl.obolibrary.org/obo/GO_0140694 GO:0140693 biolink:MolecularActivity molecular condensate scaffold activity Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate. go-plus.json http://purl.obolibrary.org/obo/GO_0140693 CHEBI:45979 biolink:ChemicalSubstance thiabendazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_45979 chebi_ph7_3 GO:0150048 biolink:CellularComponent cerebellar granule cell to Purkinje cell synapse A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum. go-plus.json cerebellar parallel fiber to Purkinje cell synapse http://purl.obolibrary.org/obo/GO_0150048 goslim_synapse GO:0140696 biolink:MolecularActivity (S)-2-hydroxyglutarate dehydrogenase activity Catalysis of the reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol. EC:1.1.5.13|RHEA:58664 go-plus.json L-2-hydroxyglutarate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0140696 GO:0150047 biolink:MolecularActivity G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. go-plus.json G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential http://purl.obolibrary.org/obo/GO_0150047 goslim_synapse CHEBI:137702 biolink:ChemicalSubstance 17-epiestriol 17-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137702 UBERON:0006799 biolink:AnatomicalEntity glandular epithelium An epithelium that is composed primarily of secretory cells. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006799 CHEBI:21990 biolink:ChemicalSubstance O(4')-glycosyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21990 CHEBI:21993 biolink:ChemicalSubstance O(4)-glycosyl-L-hydroxyproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_21993 GO:0150013 biolink:BiologicalProcess negative regulation of neuron projection arborization Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches. go-plus.json negative regulation of neuron projection branching|negative regulation of neurite branching|negative regulation of neurite arborization http://purl.obolibrary.org/obo/GO_0150013 GO:0150012 biolink:BiologicalProcess positive regulation of neuron projection arborization Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches. go-plus.json positive regulation of neurite branching|positive regulation of neurite arborization|positive regulation of neuron projection branching http://purl.obolibrary.org/obo/GO_0150012 GO:0150011 biolink:BiologicalProcess regulation of neuron projection arborization Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches. go-plus.json regulation of neurite arborization|regulation of neurite branching|regulation of neuron projection branching http://purl.obolibrary.org/obo/GO_0150011 NCBITaxon:42345 biolink:OrganismalEntity Phoenix dactylifera go-plus.json date palm http://purl.obolibrary.org/obo/NCBITaxon_42345 UBERON:0006783 biolink:AnatomicalEntity layer of superior colliculus The microstructure of the optic tectum / superior colliculus varies across species. As a general rule, there is always a clear distinction between superficial layers, which receive input primarily from the visual system and show primarily visual responses, and deeper layers, which receive many types of input and project to numerous motor-related brain areas. The distinction between these two zones is so clear and consistent that some anatomists have suggested that they should be considered separate brain structures. In mammals, neuroanatomists conventionally identify seven layers[WP]. go-plus.json cytoarchitectural part of superior colliculus|tectal layer|layer of optic tectum http://purl.obolibrary.org/obo/UBERON_0006783 GO:0150019 biolink:BiologicalProcess basal dendrite morphogenesis The process in which the anatomical structures of a basal dendrite are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0150019 GO:0150018 biolink:BiologicalProcess basal dendrite development The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0150018 GO:0150017 biolink:CellularComponent basal proximal dendrite Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma). go-plus.json http://purl.obolibrary.org/obo/GO_0150017 CHEBI:45969 biolink:ChemicalSubstance tricarballylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45969 CHEBI:70968 biolink:ChemicalSubstance 15-methylhexadecaphytosphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70968 GO:0150016 biolink:CellularComponent basal distal dendrite Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma). go-plus.json http://purl.obolibrary.org/obo/GO_0150016 GO:0150015 biolink:CellularComponent apical proximal dendrite The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma). go-plus.json http://purl.obolibrary.org/obo/GO_0150015 GO:0150014 biolink:CellularComponent apical distal dendrite Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma). go-plus.json http://purl.obolibrary.org/obo/GO_0150014 CHEBI:70964 biolink:ChemicalSubstance 8-hydroxy-dAMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_70964 CHEBI:70963 biolink:ChemicalSubstance 8-hydroxy-dADP go-plus.json http://purl.obolibrary.org/obo/CHEBI_70963 UBERON:0006786 biolink:AnatomicalEntity white matter of superior colliculus A central nervous system white matter layer that is part of a superior colliculus. go-plus.json white matter layer of superior colliculus|predominantly white regional part of superior colliculus http://purl.obolibrary.org/obo/UBERON_0006786 UBERON:0006785 biolink:AnatomicalEntity gray matter layer of superior colliculus A central nervous system gray matter layer that is part of a superior colliculus. go-plus.json gray matter of superior colliculus http://purl.obolibrary.org/obo/UBERON_0006785 CHEBI:79308 biolink:ChemicalSubstance 1-oleyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79308 GO:0150024 biolink:BiologicalProcess oxidised low-density lipoprotein particle clearance The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json oxidised LDL particle clearance|oxidized LDL particle clearance|oxidized low-density lipoprotein particle clearance|oxLDL particle clearance|ox-LDL particle clearance http://purl.obolibrary.org/obo/GO_0150024 GO:0150023 biolink:BiologicalProcess apical dendrite arborization The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches. go-plus.json http://purl.obolibrary.org/obo/GO_0150023 GO:0150022 biolink:BiologicalProcess apical dendrite development The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0150022 GO:0150021 biolink:BiologicalProcess apical dendrite morphogenesis The process in which the anatomical structures of an apical dendrite are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0150021 GO:0150020 biolink:BiologicalProcess basal dendrite arborization The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches. go-plus.json http://purl.obolibrary.org/obo/GO_0150020 CHEBI:45956 biolink:ChemicalSubstance tristearoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_45956 chebi_ph7_3 GO:0150025 biolink:MolecularActivity oxidised low-density lipoprotein particle receptor activity Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis. go-plus.json oxLDL particle receptor activity|ox-LDL particle receptor activity|ox-LDL receptor activity|oxLDL receptor activity|oxidised LDL particle receptor activity|oxidized low-density lipoprotein receptor activity|oxidized LDL receptor activity|oxidised low-density lipoprotein receptor activity|oxidized LDL particle receptor activity|oxidised LDL receptor activity|oxidized low-density lipoprotein particle receptor activity http://purl.obolibrary.org/obo/GO_0150025 CHEBI:70977 biolink:ChemicalSubstance alkane-alpha,omega-diammonium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70977 chebi_ph7_3 CHEBI:70975 biolink:ChemicalSubstance heparan sulfate alpha-D-glucosaminide 3-sulfate polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_70975 chebi_ph7_3 CHEBI:70974 biolink:ChemicalSubstance heparan sulfate N-acetyl-alpha-D-glucosaminide polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_70974 chebi_ph7_3 UBERON:0006777 biolink:AnatomicalEntity tectal plate embryologic structure that is formed by two longitudinal eminences, one on each alar plate of the midbrain. These eminences become the superior colliculus and inferior colliculus ( Carpenter-1983 )] go-plus.json quadrigeminal plate|lamina quadrigemina http://purl.obolibrary.org/obo/UBERON_0006777 CHEBI:79319 biolink:ChemicalSubstance gluconapin go-plus.json http://purl.obolibrary.org/obo/CHEBI_79319 CHEBI:80308 biolink:ChemicalSubstance Substance P go-plus.json http://purl.obolibrary.org/obo/CHEBI_80308 GO:0140665 biolink:MolecularActivity ATP-dependent H3-H4 histone complex loader activity Loading of a histone H3-H4 complex onto DNA, driven by ATP hydrolysis. go-plus.json H3-H4 histone complex loader activity|H3-H4 dimer loading activity|H3-H4 histone chaperone|histone H3-H4 dimer loading activity|histone chaperone http://purl.obolibrary.org/obo/GO_0140665 GO:0140664 biolink:MolecularActivity ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0140664 GO:0140667 biolink:BiologicalProcess regulation of oxytocin production Any process that modulates the frequency, rate, or extent of production of oxytocin. go-plus.json http://purl.obolibrary.org/obo/GO_0140667 GO:0140666 biolink:MolecularActivity annealing activity An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule. go-plus.json renaturation http://purl.obolibrary.org/obo/GO_0140666 GO:0140669 biolink:BiologicalProcess negative regulation of oxytocin production Any process that stops, prevents, or reduces the rate of production of oxytocin. go-plus.json http://purl.obolibrary.org/obo/GO_0140669 GO:0140668 biolink:BiologicalProcess positive regulation of oxytocin production Any process that activates or increases the frequency, rate or extent of production of oxytocin. go-plus.json http://purl.obolibrary.org/obo/GO_0140668 GO:0140661 biolink:MolecularActivity cytoskeletal motor inhibitor activity Binds to and stops, prevents, or reduces the activity of a motor protein. go-plus.json motor activity inhibitor activity http://purl.obolibrary.org/obo/GO_0140661 GO:0140660 biolink:MolecularActivity cytoskeletal motor activator activity Binds to and increases the activity of a motor protein. go-plus.json motor activity activator activity http://purl.obolibrary.org/obo/GO_0140660 GO:0140663 biolink:MolecularActivity ATP-dependent FeS chaperone activity Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0140663 CHEBI:70988 biolink:ChemicalSubstance N-monoacetylalkane-alpha,omega-diamine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70988 chebi_ph7_3 GO:0140662 biolink:MolecularActivity ATP-dependent protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0140662 CHEBI:21976 biolink:ChemicalSubstance o-succinylhomoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21976 CHEBI:79313 biolink:ChemicalSubstance glycosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79313 CHEBI:79312 biolink:ChemicalSubstance 18-hydroxyoleic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79312 CHEBI:21977 biolink:ChemicalSubstance O-(N-acetylglucosamine-1-phosphoryl)-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21977 CHEBI:70983 biolink:ChemicalSubstance 4-hydroxy-15-methylhexadecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70983 chebi_ph7_3 CHEBI:79316 biolink:ChemicalSubstance glucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79316 NCBITaxon:8782 biolink:OrganismalEntity Aves go-plus.json avian|birds|birds http://purl.obolibrary.org/obo/NCBITaxon_8782 CHEBI:79315 biolink:ChemicalSubstance alkenylglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79315 CHEBI:79314 biolink:ChemicalSubstance flame retardant go-plus.json http://purl.obolibrary.org/obo/CHEBI_79314 CHEBI:70980 biolink:ChemicalSubstance (R)-lactoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70980 chebi_ph7_3 CHEBI:70990 biolink:ChemicalSubstance 3-hydroxyadipyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70990 chebi_ph7_3 GO:0140654 biolink:BiologicalProcess tryprostatin A biosynthetic process The chemical reactions and pathways resulting in the formation of tryprostatin A. go-plus.json tryprostatin A anabolism|tryprostatin A biosynthesis|tryprostatin A synthesis|tryprostatin A formation http://purl.obolibrary.org/obo/GO_0140654 GO:0150002 biolink:CellularComponent distal dendrite The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma). go-plus.json http://purl.obolibrary.org/obo/GO_0150002 CHEBI:45931 biolink:ChemicalSubstance thiamine(1+) diphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_45931 GO:0140653 biolink:BiologicalProcess fumitremorgin C biosynthetic process The chemical reactions and pathways resulting in the formation of fumitremorgin C. go-plus.json fumitremorgin C anabolism|fumitremorgin C biosynthesis|fumitremorgin C synthesis|fumitremorgin C formation http://purl.obolibrary.org/obo/GO_0140653 GO:0150001 biolink:CellularComponent primary dendrite A dendrite emerging from the cell body (the soma) of a neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0150001 GO:0140656 biolink:MolecularActivity endodeoxyribonuclease activator activity Binds to and increases the activity of an endodeoxyribonuclease. go-plus.json http://purl.obolibrary.org/obo/GO_0140656 GO:0140655 biolink:BiologicalProcess mitochondrial proliferation The multiplication of mitochondria, resulting in the expansion of the number of mitochondria within a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0140655 GO:0140658 biolink:MolecularActivity ATP-dependent chromatin remodeler activity An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling. go-plus.json nucleosome-dependent ATPase activity|ATP hydrolysis-dependent chromatin remodeler activity|nucleosome-activated ATPase activity|ATPase-dependent chromatin remodeler activity http://purl.obolibrary.org/obo/GO_0140658 GO:0140657 biolink:MolecularActivity ATP-dependent activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. go-plus.json ATPase-dependent activity|ATP hydrolysis-dependent activity|ATPase activity, coupled http://purl.obolibrary.org/obo/GO_0140657 goslim_chembl|goslim_yeast|gocheck_do_not_annotate|goslim_drosophila|goslim_generic GO:0140659 biolink:MolecularActivity cytoskeletal motor regulator activity Binds to and modulates the activity of a motor protein. go-plus.json motor activity regulator activity http://purl.obolibrary.org/obo/GO_0140659 GO:0150008 biolink:BiologicalProcess bulk synaptic vesicle endocytosis Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse. go-plus.json bulk endocytosis|activity-dependent bulk endocytosis|ADBE|activity-dependent bulk synaptic vesicle endocytosis http://purl.obolibrary.org/obo/GO_0150008 GO:0150007 biolink:BiologicalProcess clathrin-dependent synaptic vesicle endocytosis Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds. go-plus.json http://purl.obolibrary.org/obo/GO_0150007 GO:0140650 biolink:BiologicalProcess radial glia-guided pyramidal neuron migration The radial migration of a pyramidal neuron along radial glial cells. go-plus.json radial glia-dependent neuronal migration http://purl.obolibrary.org/obo/GO_0140650 GO:0150006 biolink:CellularComponent urease activator complex A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function. go-plus.json http://purl.obolibrary.org/obo/GO_0150006 GO:0150005 biolink:CellularComponent enzyme activator complex A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active. go-plus.json http://purl.obolibrary.org/obo/GO_0150005 GO:0140652 biolink:BiologicalProcess pyripyropene A biosynthetic process The chemical reactions and pathways resulting in the formation of pyripyropene A. go-plus.json pyripyropene A anabolism|pyripyropene A synthesis|pyripyropene A formation|pyripyropene A biosynthesis http://purl.obolibrary.org/obo/GO_0140652 GO:0150004 biolink:CellularComponent dendritic spine origin The part of the dendritic spine neck where the spine arises from the dendritic shaft. go-plus.json http://purl.obolibrary.org/obo/GO_0150004 GO:0150003 biolink:BiologicalProcess regulation of spontaneous synaptic transmission Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0150003 GO:0140651 biolink:BiologicalProcess futile creatine cycle The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_0140651 CHEBI:70998 biolink:ChemicalSubstance G-protein-coupled receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_70998 CHEBI:79322 biolink:ChemicalSubstance thia-alkylglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79322 CHEBI:70995 biolink:ChemicalSubstance trans-13-methyltetradec-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_70995 chebi_ph7_3 CHEBI:70994 biolink:ChemicalSubstance hexacyclic triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70994 CHEBI:79327 biolink:ChemicalSubstance alkylglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79327 CHEBI:70991 biolink:ChemicalSubstance 15-methylhexadecasphing-4-enine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70991 chebi_ph7_3 GO:0140681 biolink:MolecularActivity histone H3-tri/dimethyl-lysine-36 demethylase activity Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. RHEA:60236|EC:1.14.11.69|MetaCyc: RXN-8660 go-plus.json histone H3K36me3 demethylase activity|histone H3K36me2 demethylase activity http://purl.obolibrary.org/obo/GO_0140681 GO:0140680 biolink:MolecularActivity histone H3-di/monomethyl-lysine-36 demethylase activity Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. MetaCyc: RXN-8661|RHEA:42032|EC:1.14.11.27 go-plus.json histone H3K36me demethylase activity|histone H3K36me2 demethylase activity http://purl.obolibrary.org/obo/GO_0140680 GO:0140683 biolink:MolecularActivity histone H3-di/monomethyl-lysine-9 demethylase activity Catalysis of the removal of a methyl group from a di or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. EC:1.14.11.65|RHEA:60188 go-plus.json histone H3K9me2 demethylase activity|histone H3K9me demethylase activity http://purl.obolibrary.org/obo/GO_0140683 GO:0140682 biolink:MolecularActivity histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction. EC:1.14.99.66|RHEA:60244 go-plus.json histone H3K4me demethylase activity|histone H3K4me2 demethylase activity http://purl.obolibrary.org/obo/GO_0140682 GO:0140685 biolink:MolecularActivity histone H3-di/monomethyl-lysine-9 FAD-dependent demethylase activity Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction. go-plus.json histone H3K9me2 demethylase activity|histone H3K9me demethylase activity http://purl.obolibrary.org/obo/GO_0140685 GO:0140684 biolink:MolecularActivity histone H3-tri/dimethyl-lysine-9 demethylase activity Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. EC:1.14.11.66|RHEA:60200 go-plus.json histone H3K9me3 demethylase activity|histone H3K9me2 demethylase activity http://purl.obolibrary.org/obo/GO_0140684 CHEBI:79333 biolink:ChemicalSubstance 3'-(D-alpha-aminoacyl)adenylyl zwitterionic group go-plus.json http://purl.obolibrary.org/obo/CHEBI_79333 chebi_ph7_3 CHEBI:79332 biolink:ChemicalSubstance 1-alkyl-2-acyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_79332 CHEBI:21958 biolink:ChemicalSubstance O-glycosyl-L-threonine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21958 CHEBI:21957 biolink:ChemicalSubstance O-glycosyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21957 CHEBI:79337 biolink:ChemicalSubstance 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_79337 GO:0140676 biolink:BiologicalProcess oscillatory cAMP signaling Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate. go-plus.json cAMP relay http://purl.obolibrary.org/obo/GO_0140676 GO:0140675 biolink:MolecularActivity ATP-dependent histone unloader activity Removing a histone or a histone complex from DNA. go-plus.json histone unloading activity|histone unloader activity http://purl.obolibrary.org/obo/GO_0140675 GO:0140678 biolink:MolecularActivity molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target. go-plus.json http://purl.obolibrary.org/obo/GO_0140678 GO:0140677 biolink:MolecularActivity molecular function activator activity A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target. go-plus.json http://purl.obolibrary.org/obo/GO_0140677 GO:0140679 biolink:MolecularActivity ABC-type sodium transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) -> ADP + phosphate + Na(out). TC:3.A.1.115.1|RHEA:14633|EC:7.2.2.4 go-plus.json http://purl.obolibrary.org/obo/GO_0140679 GO:0140670 biolink:MolecularActivity ATP-dependent cohesin unloading activity Facilitating a conformational change to unload a cohesin complex from sister chromatids, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0140670 GO:0140672 biolink:CellularComponent ATAC complex A chromatin remodelling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation. go-plus.json G-ATAC complex|Ada Two-A containing complex|ADA2A-containing complex|Ada-Two-A-containing complex|KAT2B-containing ATAC complex|KAT2A-containing ATAC complex|Ada two A containing complex http://purl.obolibrary.org/obo/GO_0140672 CHEBI:79342 biolink:ChemicalSubstance aralkylglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79342 GO:0140671 biolink:CellularComponent ADA complex A chromatin remodelling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and H2B. In budding yeast shares the histone acetylation (HAT) module of ADA2-GCN5-NGG1-SGF29 with the related SAGA complex. go-plus.json ADA HAT complex|Ada2/Gcn5/Ada3 transcription activator complex|ADA histone acetyltransferase complex|scADA http://purl.obolibrary.org/obo/GO_0140671 GO:0140674 biolink:MolecularActivity ATP-dependent histone loader activity Depositing a histone or a histone complex onto DNA. go-plus.json histone loading activity|histone loader activity http://purl.obolibrary.org/obo/GO_0140674 CHEBI:45912 biolink:ChemicalSubstance D-threonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_45912 chebi_ph7_3 GO:0140673 biolink:BiologicalProcess co-transcriptional chromatin reassembly The reestablishment of chromatin structure that was disrupted upon passage of RNA polymerase II during transcription elongation. This process prevents cryptic intragenic transcription initiation. go-plus.json euchromatin maintenance during transcription elongation|maintainance of chromatin integrity during transcription elongation by RNAPII|maintenance of transcriptionally active chromatin during transcription elongation|chromatin maintenance during transcription elongation http://purl.obolibrary.org/obo/GO_0140673 CHEBI:79346 biolink:ChemicalSubstance anionic ganglioside go-plus.json http://purl.obolibrary.org/obo/CHEBI_79346 CHEBI:21969 biolink:ChemicalSubstance O-phosphorylhomoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21969 CHEBI:21968 biolink:ChemicalSubstance O-phosphoamino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21968 CHEBI:79348 biolink:ChemicalSubstance hydroxy-alkenylglucosinolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79348 GO:0032959 biolink:BiologicalProcess inositol trisphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached. go-plus.json inositol trisphosphate synthesis|inositol trisphosphate formation|inositol trisphosphate biosynthesis|myo-inositol trisphosphate biosynthetic process|IP3 biosynthetic process|IP3 biosynthesis|inositol trisphosphate anabolism http://purl.obolibrary.org/obo/GO_0032959 GO:0032958 biolink:BiologicalProcess inositol phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. go-plus.json myo-inositol phosphate biosynthetic process|inositol phosphate anabolism|inositol phosphate synthesis|inositol phosphate formation|inositol phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0032958 GO:0032957 biolink:BiologicalProcess inositol trisphosphate metabolic process The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached. go-plus.json myo-inositol trisphosphate metabolic process|IP3 metabolic process|inositol trisphosphate metabolism|IP3 metabolism http://purl.obolibrary.org/obo/GO_0032957 GO:0032956 biolink:BiologicalProcess regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. go-plus.json regulation of actin cytoskeleton organization and biogenesis|regulation of actin cytoskeleton organisation http://purl.obolibrary.org/obo/GO_0032956 GO:0032955 biolink:BiologicalProcess regulation of division septum assembly Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. go-plus.json regulation of division septum formation http://purl.obolibrary.org/obo/GO_0032955 GO:0032954 biolink:BiologicalProcess regulation of cytokinetic process Any process that modulates the frequency, rate or extent of a cytokinetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0032954 GO:0032953 biolink:BiologicalProcess regulation of (1->3)-beta-D-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. go-plus.json regulation of 1,3-beta-glucan biosynthesis|regulation of 1,3-beta-glucan anabolism|regulation of 1,3-beta-glucan biosynthetic process|regulation of 1,3-beta-glucan synthesis|regulation of 1,3-beta-glucan formation http://purl.obolibrary.org/obo/GO_0032953 UBERON:0006717 biolink:AnatomicalEntity autopodial skeleton The collection of all skeletal elements in an autopodium region. go-plus.json skeleton of autopod|autopod skeleton|skeletal parts of autopod|autopodial skeleton|autopodium http://purl.obolibrary.org/obo/UBERON_0006717 UBERON:0006716 biolink:AnatomicalEntity mesopodium region The third segment of the limb, including either the wrist segment (carpus) or the ankle segment (tarsus) go-plus.json mesopodial limb segment|carpus/tarsus|mesopodial segment|mesopod http://purl.obolibrary.org/obo/UBERON_0006716 GO:0032952 biolink:BiologicalProcess regulation of (1->3)-beta-D-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans. go-plus.json regulation of 1,3-beta-glucan metabolism|regulation of (1->3)-beta-D-glucan metabolism|regulation of 1,3-beta-glucan metabolic process|regulation of 1,3-beta-D-glucan metabolic process http://purl.obolibrary.org/obo/GO_0032952 CHEBI:55380 biolink:ChemicalSubstance beta-hydroxy ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_55380 GO:0032951 biolink:BiologicalProcess regulation of beta-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans. go-plus.json regulation of beta-glucan biosynthesis|regulation of beta-glucan anabolism|regulation of beta-glucan synthesis|regulation of beta-glucan formation http://purl.obolibrary.org/obo/GO_0032951 GO:0032950 biolink:BiologicalProcess regulation of beta-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans. go-plus.json regulation of beta-glucan metabolism http://purl.obolibrary.org/obo/GO_0032950 UBERON:0006723 biolink:AnatomicalEntity cochlear modiolus the central cone shaped core of spongy bone about which turns the spiral canal go-plus.json modiolus cochleae|modiolus of cochlea|cochlea modiolus|modiolus|columella cochleae http://purl.obolibrary.org/obo/UBERON_0006723 GO:0032948 biolink:BiologicalProcess regulation of alpha-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans. go-plus.json regulation of alpha-glucan metabolism http://purl.obolibrary.org/obo/GO_0032948 GO:0032947 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032947 GO:0032946 biolink:BiologicalProcess positive regulation of mononuclear cell proliferation Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. go-plus.json up regulation of mononuclear cell proliferation|positive regulation of peripheral blood mononuclear cell proliferation|upregulation of mononuclear cell proliferation|positive regulation of PBMC proliferation|stimulation of mononuclear cell proliferation|up-regulation of mononuclear cell proliferation|activation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0032946 GO:0032945 biolink:BiologicalProcess negative regulation of mononuclear cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. go-plus.json negative regulation of peripheral blood mononuclear cell proliferation|negative regulation of PBMC proliferation http://purl.obolibrary.org/obo/GO_0032945 GO:0032944 biolink:BiologicalProcess regulation of mononuclear cell proliferation Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. go-plus.json regulation of peripheral blood mononuclear cell proliferation|regulation of PBMC proliferation http://purl.obolibrary.org/obo/GO_0032944 GO:0032943 biolink:BiologicalProcess mononuclear cell proliferation The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. go-plus.json peripheral blood mononuclear cell proliferation|PBMC proliferation http://purl.obolibrary.org/obo/GO_0032943 GO:0032942 biolink:MolecularActivity inositol tetrakisphosphate 2-kinase activity Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP. EC:2.7.1.- go-plus.json inositol 1,3,4,6-tetrakisphosphate 2-kinase activity|1D-myo-inositol-tetrakisphosphate 2-kinase activity|inositol-tetrakisphosphate 2-kinase activity http://purl.obolibrary.org/obo/GO_0032942 GO:0032941 biolink:BiologicalProcess secretion by tissue The controlled release of a substance by a tissue. go-plus.json tissue secretion|expulsion of gland contents http://purl.obolibrary.org/obo/GO_0032941 GO:0032949 biolink:BiologicalProcess regulation of alpha-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans. go-plus.json regulation of alpha-glucan biosynthesis|regulation of alpha-glucan anabolism|regulation of alpha-glucan synthesis|regulation of alpha-glucan formation http://purl.obolibrary.org/obo/GO_0032949 CHEBI:137789 biolink:ChemicalSubstance 7,12-dioxolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137789 chebi_ph7_3 CHEBI:55370 biolink:ChemicalSubstance imidazolidinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_55370 CHEBI:55373 biolink:ChemicalSubstance isoxazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_55373 GO:0032940 biolink:BiologicalProcess secretion by cell The controlled release of a substance by a cell. Wikipedia:Secretion go-plus.json cellular secretion http://purl.obolibrary.org/obo/GO_0032940 CHEBI:55377 biolink:ChemicalSubstance beta-hematin go-plus.json http://purl.obolibrary.org/obo/CHEBI_55377 chebi_ph7_3 CHEBI:55376 biolink:ChemicalSubstance ferriheme b(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_55376 chebi_ph7_3 GO:0150093 biolink:BiologicalProcess amyloid-beta clearance by transcytosis The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0150093 GO:0032937 biolink:CellularComponent SREBP-SCAP-Insig complex A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0032937 GO:0150092 biolink:BiologicalProcess regulation of synaptic scaling A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell. go-plus.json regulation of homeostatic synaptic scaling|homeostatic synaptic scaling http://purl.obolibrary.org/obo/GO_0150092 GO:0032936 biolink:CellularComponent SREBP-SCAP complex A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. go-plus.json Sre1-Scp1 complex http://purl.obolibrary.org/obo/GO_0032936 GO:0032935 biolink:MolecularActivity sterol sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of a sterol. go-plus.json sterol-sensing domain http://purl.obolibrary.org/obo/GO_0032935 GO:0150091 biolink:BiologicalProcess multiple spine synapse organization, multiple dendrites A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites. go-plus.json http://purl.obolibrary.org/obo/GO_0150091 GO:0150090 biolink:BiologicalProcess multiple spine synapse organization, single dendrite A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite. go-plus.json http://purl.obolibrary.org/obo/GO_0150090 GO:0032934 biolink:MolecularActivity sterol binding Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. go-plus.json sterol carrier activity http://purl.obolibrary.org/obo/GO_0032934 GO:0032933 biolink:BiologicalProcess SREBP signaling pathway A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription. go-plus.json SREBP signalling|sterol regulatory element binding protein target gene transcriptional activation|upregulation of sterol regulatory element binding protein target gene transcription|positive regulation of sterol regulatory element binding protein target gene transcription|positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response|up regulation of sterol regulatory element binding protein target gene transcription|sterol response element binding protein signaling pathway|activation of sterol regulatory element binding protein target gene transcription|positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway|positive regulation of transcription via sterol regulatory element binding|stimulation of sterol regulatory element binding protein target gene transcription|endoplasmic reticulum-nuclear sterol response pathway|SREBP-mediated signaling pathway|sterol depletion response, SREBP target gene transcriptional activation|ER-nuclear sterol response pathway|up-regulation of sterol regulatory element binding protein target gene transcription|SREBP target gene transcriptional activation|ER to nucleus sterol response pathway|SREBP-mediated signalling pathway|endoplasmic reticulum to nucleus sterol response pathway http://purl.obolibrary.org/obo/GO_0032933 GO:0032932 biolink:BiologicalProcess negative regulation of astral microtubule depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules. go-plus.json astral microtubule stabilization http://purl.obolibrary.org/obo/GO_0032932 GO:0032931 biolink:MolecularActivity histone acetyltransferase activity (H3-K56 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56). go-plus.json histone lysine N-acetyltransferase activity (H3-K56 specific) http://purl.obolibrary.org/obo/GO_0032931 GO:0032930 biolink:BiologicalProcess positive regulation of superoxide anion generation Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell. go-plus.json upregulation of superoxide release|stimulation of superoxide release|activation of superoxide release|positive regulation of superoxide release|up-regulation of superoxide release|up regulation of superoxide release http://purl.obolibrary.org/obo/GO_0032930 GO:0150099 biolink:BiologicalProcess neuron-glial cell signaling Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine. go-plus.json neurone-glia signaling|neuron-glia signaling|neuron-glial cell signalling|neurone-glial cell signalling|neurone-glial cell signaling|neuron-glia signalling|neurone-glia signalling http://purl.obolibrary.org/obo/GO_0150099 GO:0150098 biolink:BiologicalProcess glial cell-neuron signaling Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum. go-plus.json glial cell-neurone signalling|glial cell- neuron signalling|glial cell-neurone singaling|glia-neuron signaling|glia-neurone signaling|glia-neurone signalling|glia-neuron signalling http://purl.obolibrary.org/obo/GO_0150098 GO:0032939 biolink:BiologicalProcess positive regulation of translation in response to oxidative stress Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json up-regulation of translation in response to oxidative stress|upregulation of translation in response to oxidative stress|up regulation of translation in response to oxidative stress|activation of translation in response to oxidative stress|stimulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032939 GO:0150094 biolink:BiologicalProcess amyloid-beta clearance by cellular catabolic process The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation. go-plus.json amyloid-beta clearance by phagocytosis http://purl.obolibrary.org/obo/GO_0150094 GO:0032938 biolink:BiologicalProcess negative regulation of translation in response to oxidative stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. go-plus.json http://purl.obolibrary.org/obo/GO_0032938 CHEBI:55360 biolink:ChemicalSubstance beta-alaninamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_55360 CHEBI:55367 biolink:ChemicalSubstance deoxyribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_55367 CHEBI:55366 biolink:ChemicalSubstance ribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_55366 GO:0032926 biolink:BiologicalProcess negative regulation of activin receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway. go-plus.json down regulation of activin receptor signaling pathway|inhibition of activin receptor signaling pathway|negative regulation of activin signaling pathway|negative regulation of activin signalling pathway|down-regulation of activin receptor signaling pathway|negative regulation of activin receptor signalling pathway|downregulation of activin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0032926 GO:0032925 biolink:BiologicalProcess regulation of activin receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway. go-plus.json regulation of activin signaling pathway|regulation of activin receptor signalling pathway|regulation of activin signalling pathway http://purl.obolibrary.org/obo/GO_0032925 GO:0032924 biolink:BiologicalProcess activin receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json activin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0032924 GO:0032923 biolink:BiologicalProcess organic phosphonate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. go-plus.json organophosphonate biosynthetic process http://purl.obolibrary.org/obo/GO_0032923 GO:0032922 biolink:BiologicalProcess circadian regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours. go-plus.json diurnal variation of gene expression|circadian regulation of protein expression|diurnal variation of protein expression http://purl.obolibrary.org/obo/GO_0032922 GO:0032921 biolink:CellularComponent sarcosine oxidase complex A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0032921 GO:0032920 biolink:BiologicalProcess putrescine acetylation The modification of putrescine by addition of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0032920 GO:0032929 biolink:BiologicalProcess negative regulation of superoxide anion generation Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell. go-plus.json down-regulation of superoxide release|downregulation of superoxide release|down regulation of superoxide release|inhibition of superoxide release|negative regulation of superoxide release http://purl.obolibrary.org/obo/GO_0032929 GO:0032928 biolink:BiologicalProcess regulation of superoxide anion generation Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell. go-plus.json regulation of superoxide release http://purl.obolibrary.org/obo/GO_0032928 GO:0032927 biolink:BiologicalProcess positive regulation of activin receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway. go-plus.json upregulation of activin receptor signaling pathway|positive regulation of activin signaling pathway|stimulation of activin receptor signaling pathway|up-regulation of activin receptor signaling pathway|activation of activin receptor signaling pathway|positive regulation of activin signalling pathway|positive regulation of activin receptor signalling pathway|up regulation of activin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0032927 CHEBI:55357 biolink:ChemicalSubstance (R)-piperazine-2-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55357 CHEBI:55356 biolink:ChemicalSubstance (R)-piperazine-2-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_55356 CHEBI:55359 biolink:ChemicalSubstance (R)-N-tert-butylpiperazine-2-carboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_55359 CHEBI:55358 biolink:ChemicalSubstance (R)-piperazine-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55358 CHEBI:55353 biolink:ChemicalSubstance (2E)-but-2-ene-1,2,3-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55353 CHEBI:55355 biolink:ChemicalSubstance 7-chloro-D-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_55355 CHEBI:55354 biolink:ChemicalSubstance 7-chlorotryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_55354 GO:0032915 biolink:BiologicalProcess positive regulation of transforming growth factor beta2 production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2. go-plus.json up-regulation of transforming growth factor-beta2 production|positive regulation of transforming growth factor-beta2 production|upregulation of transforming growth factor-beta2 production|positive regulation of TGF-B2 production|positive regulation of TGFB2 production|up regulation of transforming growth factor-beta2 production|activation of transforming growth factor-beta2 production|stimulation of transforming growth factor-beta2 production http://purl.obolibrary.org/obo/GO_0032915 GO:0150071 biolink:BiologicalProcess negative regulation of arginase activity Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150071 GO:0150070 biolink:BiologicalProcess regulation of arginase activity Any process that modulates the frequency, rate or extent of arginase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150070 GO:0032914 biolink:BiologicalProcess positive regulation of transforming growth factor beta1 production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1. go-plus.json activation of transforming growth factor-beta1 production|upregulation of transforming growth factor-beta1 production|positive regulation of TGF-B1 production|positive regulation of TGFB1 production|up regulation of transforming growth factor-beta1 production|stimulation of transforming growth factor-beta1 production|up-regulation of transforming growth factor-beta1 production http://purl.obolibrary.org/obo/GO_0032914 GO:0032913 biolink:BiologicalProcess negative regulation of transforming growth factor beta3 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3. go-plus.json inhibition of transforming growth factor-beta3 production|negative regulation of transforming growth factor-beta3 production|down regulation of transforming growth factor-beta3 production|negative regulation of TGFB3 production|negative regulation of TGF-B3 production|downregulation of transforming growth factor-beta3 production|down-regulation of transforming growth factor-beta3 production http://purl.obolibrary.org/obo/GO_0032913 GO:0032912 biolink:BiologicalProcess negative regulation of transforming growth factor beta2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2. go-plus.json negative regulation of transforming growth factor-beta2 production|down regulation of transforming growth factor-beta2 production|negative regulation of TGFB2 production|negative regulation of TGF-B2 production|downregulation of transforming growth factor-beta2 production|down-regulation of transforming growth factor-beta2 production|inhibition of transforming growth factor-beta2 production http://purl.obolibrary.org/obo/GO_0032912 GO:0032911 biolink:BiologicalProcess negative regulation of transforming growth factor beta1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1. go-plus.json negative regulation of transforming growth factor-beta1 production|down regulation of transforming growth factor-beta1 production|negative regulation of TGFB1 production|negative regulation of TGF-B1 production|downregulation of transforming growth factor-beta1 production|down-regulation of transforming growth factor-beta1 production|inhibition of transforming growth factor-beta1 production http://purl.obolibrary.org/obo/GO_0032911 GO:0032910 biolink:BiologicalProcess regulation of transforming growth factor beta3 production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3. go-plus.json regulation of TGF-B3 production|regulation of TGFB3 production|regulation of transforming growth factor-beta3 production http://purl.obolibrary.org/obo/GO_0032910 GO:0150079 biolink:BiologicalProcess negative regulation of neuroinflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0150079 GO:0150078 biolink:BiologicalProcess positive regulation of neuroinflammatory response Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0150078 GO:0150077 biolink:BiologicalProcess regulation of neuroinflammatory response Any process that modulates the frequency, rate or extent of neuroinflammatory response. go-plus.json http://purl.obolibrary.org/obo/GO_0150077 GO:0150076 biolink:BiologicalProcess neuroinflammatory response The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. go-plus.json nerve tissue inflammatory response|nervous tissue inflammatory response|neural tissue inflammatory response http://purl.obolibrary.org/obo/GO_0150076 GO:0150075 biolink:BiologicalProcess negative regulation of protein-glutamine gamma-glutamyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150075 GO:0032919 biolink:BiologicalProcess spermine acetylation The modification of spermine by addition of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0032919 GO:0150074 biolink:BiologicalProcess positive regulation of protein-glutamine gamma-glutamyltransferase activity Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150074 GO:0032918 biolink:BiologicalProcess spermidine acetylation The modification of spermidine by addition of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0032918 GO:0150073 biolink:BiologicalProcess regulation of protein-glutamine gamma-glutamyltransferase activity Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150073 GO:0032917 biolink:BiologicalProcess polyamine acetylation The modification of polyamines by addition of acetyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0032917 GO:0150072 biolink:BiologicalProcess positive regulation of arginase activity Any process that activates or increases the frequency, rate or extent of arginase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150072 GO:0032916 biolink:BiologicalProcess positive regulation of transforming growth factor beta3 production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3. go-plus.json up-regulation of transforming growth factor-beta3 production|positive regulation of transforming growth factor-beta3 production|upregulation of transforming growth factor-beta3 production|positive regulation of TGF-B3 production|positive regulation of TGFB3 production|up regulation of transforming growth factor-beta3 production|activation of transforming growth factor-beta3 production|stimulation of transforming growth factor-beta3 production http://purl.obolibrary.org/obo/GO_0032916 UBERON:0006761 biolink:AnatomicalEntity corneo-scleral junction the edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm go-plus.json corneal limbus|corneal-scleral limbus|corneoscleral junction|sclerocorneal junction|limbus corneae|sclerocorneal limbus|limbus corneae|cornea limbus http://purl.obolibrary.org/obo/UBERON_0006761 CHEBI:137732 biolink:ChemicalSubstance 5-carboxy-dCMP(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137732 chebi_ph7_3 CHEBI:137731 biolink:ChemicalSubstance 5-formyl-dCMP(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137731 chebi_ph7_3 NCBITaxon:91347 biolink:OrganismalEntity Enterobacterales go-plus.json Enterobacteriaceae group|Enterobacteriales|Enterobacteriaceae and related endosymbionts|gamma-3 proteobacteria http://purl.obolibrary.org/obo/NCBITaxon_91347 UBERON:0006763 biolink:AnatomicalEntity epithelium of conjunctiva Layer of nonkeratinized squamous epithelium lining the conjunctiva, overlying scleral tissue go-plus.json conjunctiva epithelium|conjunctival epithelium http://purl.obolibrary.org/obo/UBERON_0006763 GO:0032904 biolink:BiologicalProcess negative regulation of nerve growth factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF). go-plus.json negative regulation of NGF production|down-regulation of nerve growth factor production|downregulation of nerve growth factor production|down regulation of nerve growth factor production|inhibition of nerve growth factor production http://purl.obolibrary.org/obo/GO_0032904 GO:0032903 biolink:BiologicalProcess regulation of nerve growth factor production Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF). go-plus.json regulation of beta-nerve growth factor production|regulation of NGF production http://purl.obolibrary.org/obo/GO_0032903 GO:0032902 biolink:BiologicalProcess nerve growth factor production The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. go-plus.json NGF production|beta-nerve growth factor production http://purl.obolibrary.org/obo/GO_0032902 GO:0032901 biolink:BiologicalProcess positive regulation of neurotrophin production Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin. go-plus.json up regulation of neurotrophin production|activation of neurotrophin production|stimulation of neurotrophin production|up-regulation of neurotrophin production|upregulation of neurotrophin production http://purl.obolibrary.org/obo/GO_0032901 GO:0032900 biolink:BiologicalProcess negative regulation of neurotrophin production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin. go-plus.json downregulation of neurotrophin production|down-regulation of neurotrophin production|inhibition of neurotrophin production|down regulation of neurotrophin production http://purl.obolibrary.org/obo/GO_0032900 GO:0150089 biolink:BiologicalProcess multiple spine synapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines. go-plus.json multi-synaptic organisation|multisynapse organisation|multisynaptic organisation|multiple spine synapse organisation|multi-synaptic organization|multi-synapse organisation|multisynapse organization|multisynaptic organization|multi-synapse organization http://purl.obolibrary.org/obo/GO_0150089 GO:0150088 biolink:CellularComponent multiple synapse bouton, contacting multiple dendrites A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites. go-plus.json MSB2|type 2 multisynaptic bouton|type 2 multi-synaptic bouton|type 2 multiple-synapse bouton|type 2 multi-synapse bouton|type 2 multisynapse bouton|type 2 multiple spine synapse bouton http://purl.obolibrary.org/obo/GO_0150088 GO:0150087 biolink:CellularComponent multiple synapse bouton, contacting single dendrite A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite. go-plus.json MSB1|type 1 multisynaptic bouton|type 1 multi-synaptic bouton|type 1 multi-synapse bouton|type 1 multiple-synapse bouton|type 1 multisynapse bouton|type 1 multiple spine synapse bouton http://purl.obolibrary.org/obo/GO_0150087 GO:0032909 biolink:BiologicalProcess regulation of transforming growth factor beta2 production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2. go-plus.json regulation of TGFB2 production|regulation of transforming growth factor-beta2 production|regulation of TGF-B2 production http://purl.obolibrary.org/obo/GO_0032909 GO:0150086 biolink:CellularComponent multiple synapse bouton A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites. go-plus.json multi-synaptic bouton|multiple-synapse bouton|MSB|multisynaptic bouton|multisynapse bouton|multi-synapse bouton|multiple synapse|multi-synapse|multiple spine synapse bouton|multisynapse http://purl.obolibrary.org/obo/GO_0150086 GO:0032908 biolink:BiologicalProcess regulation of transforming growth factor beta1 production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1. go-plus.json regulation of TGFB1 production|regulation of transforming growth factor-beta1 production|regulation of TGF-B1 production http://purl.obolibrary.org/obo/GO_0032908 GO:0032907 biolink:BiologicalProcess transforming growth factor beta3 production The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TGFB3 production|transforming growth factor-beta3 production|TGF-B3 production http://purl.obolibrary.org/obo/GO_0032907 GO:0032906 biolink:BiologicalProcess transforming growth factor beta2 production The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TGF-B2 production|TGFB2 production|transforming growth factor-beta2 production http://purl.obolibrary.org/obo/GO_0032906 GO:0032905 biolink:BiologicalProcess transforming growth factor beta1 production The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TGF-B1 production|TGFB1 production|transforming growth factor-beta1 production http://purl.obolibrary.org/obo/GO_0032905 CHEBI:137748 biolink:ChemicalSubstance UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137748 chebi_ph7_3 CHEBI:55335 biolink:ChemicalSubstance ternatin C5 go-plus.json http://purl.obolibrary.org/obo/CHEBI_55335 CHEBI:55334 biolink:ChemicalSubstance delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_55334 UBERON:0006757 biolink:AnatomicalEntity lateral lingual swelling During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line. go-plus.json tuberculum linguale laterale|lateral lingual prominence|tuberculum laterale|lateral swellings http://purl.obolibrary.org/obo/UBERON_0006757 CHEBI:55337 biolink:ChemicalSubstance all-trans-polyprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55337 CHEBI:55336 biolink:ChemicalSubstance delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_55336 UBERON:0006756 biolink:AnatomicalEntity median lingual swelling During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]. go-plus.json tuberculum linguale mediale|median lingual swelling|median tongue bud|tuberculum impar http://purl.obolibrary.org/obo/UBERON_0006756 CHEBI:55331 biolink:ChemicalSubstance 16-feruloyloxypalmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55331 chebi_ph7_3 CHEBI:3110 biolink:ChemicalSubstance biotinyl-5'-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_3110 CHEBI:137740 biolink:ChemicalSubstance UDP-3-O-[(3R)-hydroxyacyl]-alpha-D-glucosamine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137740 chebi_ph7_3 CHEBI:55330 biolink:ChemicalSubstance 16-feruloyloxypalmitic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55330 CHEBI:55333 biolink:ChemicalSubstance glycosylrhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55333 CHEBI:55332 biolink:ChemicalSubstance beta-D-galactosyl-(1->4)-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_55332 chebi_ph7_3 CHEBI:55328 biolink:ChemicalSubstance 16-hydroxyhexadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_55328 CHEBI:55327 biolink:ChemicalSubstance aci-nitroethane(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_55327 CHEBI:31359 biolink:ChemicalSubstance carminomycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31359 CHEBI:55329 biolink:ChemicalSubstance 16-hydroxyhexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_55329 chebi_ph7_3 GO:0150057 biolink:CellularComponent amylin receptor complex 2 A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM). go-plus.json AMY2 complex http://purl.obolibrary.org/obo/GO_0150057 GO:0150056 biolink:CellularComponent amylin receptor complex 1 A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM). go-plus.json AMY1 complex http://purl.obolibrary.org/obo/GO_0150056 GO:0150054 biolink:BiologicalProcess regulation of postsynaptic neurotransmitter receptor diffusion trapping Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping. go-plus.json http://purl.obolibrary.org/obo/GO_0150054 goslim_synapse GO:0150053 biolink:CellularComponent cerebellar climbing fiber to Purkinje cell synapse A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata. go-plus.json cerebellar climbing fibre to Purkinje cell synapse http://purl.obolibrary.org/obo/GO_0150053 goslim_synapse GO:0150052 biolink:BiologicalProcess regulation of postsynapse assembly Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0150052 goslim_synapse GO:0150051 biolink:CellularComponent postsynaptic Golgi apparatus The network of the Golgi apparatus structures located within the postsynapse. go-plus.json Golgi outpost http://purl.obolibrary.org/obo/GO_0150051 goslim_synapse GO:0150050 biolink:CellularComponent postsynaptic septin cytoskeleton The portion of the septin cytoskeleton contained within the postsynapse. go-plus.json http://purl.obolibrary.org/obo/GO_0150050 goslim_synapse GO:0150059 biolink:BiologicalProcess amylin receptor 1 signaling pathway A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM). go-plus.json AMY1 signaling pathway http://purl.obolibrary.org/obo/GO_0150059 GO:0150058 biolink:CellularComponent amylin receptor complex 3 A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signalling pathways. go-plus.json AMY3 complex http://purl.obolibrary.org/obo/GO_0150058 CHEBI:55324 biolink:ChemicalSubstance gastrointestinal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_55324 CHEBI:55323 biolink:ChemicalSubstance antidiarrhoeal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_55323 CHEBI:31355 biolink:ChemicalSubstance carboplatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31355 CHEBI:55322 biolink:ChemicalSubstance mu-opioid receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_55322 GO:0150060 biolink:BiologicalProcess amylin receptor 2 signaling pathway A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM). go-plus.json AMY2 signaling pathway http://purl.obolibrary.org/obo/GO_0150060 GO:0150068 biolink:BiologicalProcess positive regulation of tubulin deacetylase activity Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150068 GO:0150067 biolink:BiologicalProcess regulation of tubulin deacetylase activity Any process that modulates the frequency, rate or extent of tubulin deacetylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150067 GO:0150066 biolink:BiologicalProcess negative regulation of deacetylase activity Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150066 CHEBI:45996 biolink:ChemicalSubstance ribothymidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_45996 chebi_ph7_3 GO:0150065 biolink:BiologicalProcess regulation of deacetylase activity Any process that modulates the frequency, rate or extent of deacetylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150065 GO:0150064 biolink:BiologicalProcess vertebrate eye-specific patterning Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus. go-plus.json binocular vision development|eye-specific segregation|eye-specific patterning|vertebrate eye-specific segregation http://purl.obolibrary.org/obo/GO_0150064 GO:0150063 biolink:BiologicalProcess visual system development The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. go-plus.json visual pathway development|optic pathway development http://purl.obolibrary.org/obo/GO_0150063 GO:0150062 biolink:BiologicalProcess complement-mediated synapse pruning Synaptic pruning mediated by complement system signalling. go-plus.json synapse elimination|synapse clearance|synapse disassembly|synapse removal|complement-dependent synapse pruning http://purl.obolibrary.org/obo/GO_0150062 GO:0150061 biolink:BiologicalProcess amylin receptor 3 signaling pathway A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos. go-plus.json AMY3 signaling pathway http://purl.obolibrary.org/obo/GO_0150061 CHEBI:137723 biolink:ChemicalSubstance 16-epiestriol 16-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137723 CHEBI:137720 biolink:ChemicalSubstance 16-epiestriol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137720 CHEBI:137724 biolink:ChemicalSubstance 7-oxotaurolithocholate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137724 chebi_ph7_3 GO:0150069 biolink:BiologicalProcess negative regulation of tubulin deacetylase activity Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0150069 CHEBI:55310 biolink:ChemicalSubstance poly(2,5-ethylene furandicarboxylate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_55310 chebi_ph7_3 GO:0042480 biolink:BiologicalProcess negative regulation of eye photoreceptor cell development Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. go-plus.json downregulation of eye photoreceptor cell development|down regulation of eye photoreceptor cell development|inhibition of eye photoreceptor cell development|negative regulation of eye photoreceptor development|down-regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0042480 GO:0042486 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042486 GO:0042485 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042485 GO:0042488 biolink:BiologicalProcess positive regulation of odontogenesis of dentin-containing tooth Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. go-plus.json up regulation of odontogenesis|positive regulation of odontogenesis of dentine-containing teeth|activation of odontogenesis|positive regulation of odontogenesis of dentine-containing tooth|stimulation of odontogenesis|up-regulation of odontogenesis|upregulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042488 GO:0042487 biolink:BiologicalProcess regulation of odontogenesis of dentin-containing tooth Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. go-plus.json regulation of odontogenesis of dentine-containing teeth|regulation of odontogenesis of dentine-containing tooth http://purl.obolibrary.org/obo/GO_0042487 GO:0042482 biolink:BiologicalProcess positive regulation of odontogenesis Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. go-plus.json stimulation of odontogenesis|up-regulation of odontogenesis|positive regulation of odontogenesis of calcareous or chitinous tooth|upregulation of odontogenesis|positive regulation of tooth development|up regulation of odontogenesis|activation of odontogenesis http://purl.obolibrary.org/obo/GO_0042482 GO:0042481 biolink:BiologicalProcess regulation of odontogenesis Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. go-plus.json regulation of tooth development|regulation of odontogenesis of calcareous or chitinous tooth http://purl.obolibrary.org/obo/GO_0042481 GO:0042484 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042484 GO:0042483 biolink:BiologicalProcess negative regulation of odontogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. go-plus.json down-regulation of odontogenesis|negative regulation of odontogenesis of calcareous or chitinous tooth|inhibition of odontogenesis|down regulation of odontogenesis|negative regulation of tooth development|downregulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042483 GO:0042489 biolink:BiologicalProcess negative regulation of odontogenesis of dentin-containing tooth Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx. go-plus.json down regulation of odontogenesis|downregulation of odontogenesis|down-regulation of odontogenesis|negative regulation of odontogenesis|negative regulation of odontogenesis of dentine-containing teeth|negative regulation of odontogenesis of dentine-containing tooth|inhibition of odontogenesis http://purl.obolibrary.org/obo/GO_0042489 CHEBI:137373 biolink:ChemicalSubstance Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137373 chebi_ph7_3 CHEBI:137372 biolink:ChemicalSubstance pyridinium-3,5-bisthiocarboxylate mononucleotide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137372 chebi_ph7_3 CHEBI:137376 biolink:ChemicalSubstance long-chain fatty acyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_137376 GO:0042491 biolink:BiologicalProcess inner ear auditory receptor cell differentiation The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell. go-plus.json auditory receptor cell differentiation|auditory hair cell differentiation http://purl.obolibrary.org/obo/GO_0042491 GO:0042490 biolink:BiologicalProcess mechanoreceptor differentiation The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. go-plus.json http://purl.obolibrary.org/obo/GO_0042490 CHEBI:137391 biolink:ChemicalSubstance 18-hydroxyleukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137391 chebi_ph7_3 CHEBI:137390 biolink:ChemicalSubstance 19-hydroxyleukotriene B4(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137390 chebi_ph7_3 GO:0042497 biolink:MolecularActivity triacyl lipopeptide binding Binding to a lipopeptide containing a nonprotein moiety consisting of three acyl groups. go-plus.json triacylated lipopeptide binding|bacterial triacyl lipopeptide binding|bacterial triacyl lipoprotein binding http://purl.obolibrary.org/obo/GO_0042497 GO:0042496 biolink:BiologicalProcess detection of diacyl bacterial lipopeptide The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups. go-plus.json detection of diacylated bacterial lipoprotein|perception of diacylated bacterial lipoprotein|perception of diacylated bacterial lipopeptide http://purl.obolibrary.org/obo/GO_0042496 GO:0042499 biolink:MolecularActivity obsolete signal peptide peptidase activity OBSOLETE. Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein. go-plus.json signal peptide peptidase activity|SPP http://purl.obolibrary.org/obo/GO_0042499 GO:0042498 biolink:MolecularActivity diacyl lipopeptide binding Binding to a lipopeptide containing a nonprotein moiety consisting of two acyl groups. go-plus.json diacylated lipopeptide binding|bacterial diacyl lipoprotein binding|bacterial diacyl lipopeptide binding http://purl.obolibrary.org/obo/GO_0042498 GO:0042493 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042493 GO:0042492 biolink:BiologicalProcess gamma-delta T cell differentiation The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex. go-plus.json gamma-delta T-lymphocyte differentiation|gamma-delta T cell development|gamma-delta T lymphocyte differentiation|gamma-delta T-cell differentiation http://purl.obolibrary.org/obo/GO_0042492 GO:0042495 biolink:BiologicalProcess detection of triacyl bacterial lipopeptide The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups. go-plus.json perception of triacylated bacterial lipoprotein|perception of triacylated bacterial lipopeptide|detection of triacylated bacterial lipoprotein http://purl.obolibrary.org/obo/GO_0042495 GO:0042494 biolink:BiologicalProcess detection of bacterial lipoprotein The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs). go-plus.json perception of bacterial lipoprotein|perception of Lpp|detection of Lpp|perception of BLP|detection of BLP http://purl.obolibrary.org/obo/GO_0042494 CHEBI:137385 biolink:ChemicalSubstance (24S)-hydroxycholesterol 24-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137385 CHEBI:137389 biolink:ChemicalSubstance (24S)-hydroxycholesterol 3,24-disulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137389 CHEBI:137388 biolink:ChemicalSubstance (24S)-hydroxycholesterol 3-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137388 CHEBI:137387 biolink:ChemicalSubstance 4-O-methyl-dTMP(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137387 chebi_ph7_3 CHEBI:137386 biolink:ChemicalSubstance thymidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137386 chebi_ph7_3 BSPO:0000099 biolink:OntologyClass posterior_to x posterior_to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail. BSPO:0000099 go-plus.json caudal_to http://purl.obolibrary.org/obo/BSPO_0000099 BSPO:0000098 biolink:OntologyClass dorsal_to x dorsal_to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly). BSPO:0000098 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000098 CHEBI:137358 biolink:ChemicalSubstance 1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137358 chebi_ph7_3 CHEBI:137357 biolink:ChemicalSubstance S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137357 chebi_ph7_3 CHEBI:137351 biolink:ChemicalSubstance 5-hydroxymethyldeoxycytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137351 CHEBI:137356 biolink:ChemicalSubstance S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137356 chebi_ph7_3 CHEBI:137355 biolink:ChemicalSubstance 5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137355 chebi_ph7_3 BSPO:0000097 biolink:OntologyClass distal_to x distal_to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal). BSPO:0000097 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000097 CHEBI:137353 biolink:ChemicalSubstance pyridinium-3,5-biscarboxylate mononucleotide(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137353 chebi_ph7_3 BSPO:0000096 biolink:OntologyClass anterior_to x anterior_to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail: bearer BSPO:0000096 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000096 CHEBI:137370 biolink:ChemicalSubstance 20-hydroxyprostaglandin E2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137370 CHEBI:137336 biolink:ChemicalSubstance 8-amino-8-demethylriboflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_137336 CHEBI:137333 biolink:ChemicalSubstance anaerobilin go-plus.json http://purl.obolibrary.org/obo/CHEBI_137333 CHEBI:137340 biolink:ChemicalSubstance 8-demethyl-8-(methylamino)riboflavin go-plus.json http://purl.obolibrary.org/obo/CHEBI_137340 CHEBI:137345 biolink:ChemicalSubstance 13-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_137345 CHEBI:137344 biolink:ChemicalSubstance 7-HETE go-plus.json http://purl.obolibrary.org/obo/CHEBI_137344 CHEBI:137343 biolink:ChemicalSubstance (R)-2-(phosphonomethyl)malic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137343 CHEBI:137342 biolink:ChemicalSubstance 13-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137342 chebi_ph7_3 CHEBI:137310 biolink:ChemicalSubstance 3-(methylaminomethyl)indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_137310 CHEBI:137328 biolink:ChemicalSubstance epoxy(hydroxy)icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137328 chebi_ph7_3 CHEBI:137323 biolink:ChemicalSubstance O-(alpha-D-mannosyl)-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137323 chebi_ph7_3 CHEBI:137321 biolink:ChemicalSubstance O-(alpha-D-mannosyl)-L-serine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137321 chebi_ph7_3 CHEBI:137320 biolink:ChemicalSubstance (13S)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-icosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137320 chebi_ph7_3 NCBITaxon:451435 biolink:OrganismalEntity Chytridiomycetes go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_451435 GO:0042400 biolink:BiologicalProcess ectoine catabolic process The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. go-plus.json ectoine catabolism|ectoine breakdown|ectoine degradation http://purl.obolibrary.org/obo/GO_0042400 GO:0042406 biolink:CellularComponent extrinsic component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. go-plus.json extrinsic to ER membrane|extrinsic to endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0042406 GO:0042405 biolink:CellularComponent nuclear inclusion body An intranuclear focus at which aggregated proteins have been sequestered. go-plus.json http://purl.obolibrary.org/obo/GO_0042405 CHEBI:45906 biolink:ChemicalSubstance suramin go-plus.json http://purl.obolibrary.org/obo/CHEBI_45906 GO:0042408 biolink:MolecularActivity obsolete myrcene/(E)-beta-ocimene synthase activity OBSOLETE. Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes. EC:4.6.-.- go-plus.json myrcene/ocimene synthase activity|myrcene/(E)-beta-ocimene synthase activity http://purl.obolibrary.org/obo/GO_0042408 GO:0042407 biolink:BiologicalProcess cristae formation The assembly of cristae, the inwards folds of the inner mitochondrial membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0042407 GO:0042402 biolink:BiologicalProcess cellular biogenic amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. go-plus.json biogenic amine degradation|biogenic amine catabolism|biogenic amine breakdown http://purl.obolibrary.org/obo/GO_0042402 GO:0042401 biolink:BiologicalProcess cellular biogenic amine biosynthetic process The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. go-plus.json biogenic amine synthesis|biogenic amine formation|biogenic amine biosynthesis|biogenic amine anabolism http://purl.obolibrary.org/obo/GO_0042401 GO:0042404 biolink:BiologicalProcess thyroid hormone catabolic process The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. go-plus.json thyroid hormone degradation|thyroid hormone breakdown|thyroid hormone catabolism http://purl.obolibrary.org/obo/GO_0042404 GO:0042403 biolink:BiologicalProcess thyroid hormone metabolic process The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. go-plus.json thyroid hormone metabolism http://purl.obolibrary.org/obo/GO_0042403 GO:0042409 biolink:MolecularActivity caffeoyl-CoA O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA. EC:2.1.1.104|RHEA:16925|MetaCyc:CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN go-plus.json S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity|trans-caffeoyl-CoA 3-O-methyltransferase activity|caffeoyl-CoA 3-O-methyltransferase activity|caffeoyl coenzyme A methyltransferase activity http://purl.obolibrary.org/obo/GO_0042409 CHEBI:176910 biolink:ChemicalSubstance fatty acyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_176910 GO:0042411 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042411 GO:0042410 biolink:MolecularActivity 6-carboxyhexanoate-CoA ligase activity Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA. KEGG_REACTION:R03209|EC:6.2.1.14|MetaCyc:6-CARBOXYHEXANOATE--COA-LIGASE-RXN|RHEA:14781 go-plus.json pimeloyl-CoA synthetase activity|6-carboxyhexanoyl-CoA synthetase activity|6-carboxyhexanoate:CoA ligase (AMP-forming)|pimelyl-CoA synthetase activity http://purl.obolibrary.org/obo/GO_0042410 GO:0042417 biolink:BiologicalProcess dopamine metabolic process The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. go-plus.json dopamine metabolism http://purl.obolibrary.org/obo/GO_0042417 GO:0042416 biolink:BiologicalProcess dopamine biosynthetic process The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. go-plus.json dopamine anabolism|dopamine synthesis|dopamine formation|dopamine biosynthesis http://purl.obolibrary.org/obo/GO_0042416 GO:0042419 biolink:BiologicalProcess epinephrine catabolic process The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. go-plus.json epinephrine breakdown|adrenaline catabolic process|epinephrine catabolism|adrenaline catabolism|epinephrine degradation http://purl.obolibrary.org/obo/GO_0042419 GO:0042418 biolink:BiologicalProcess epinephrine biosynthetic process The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. go-plus.json epinephrine anabolism|epinephrine biosynthesis|adrenaline biosynthetic process|epinephrine synthesis|adrenaline biosynthesis|epinephrine formation http://purl.obolibrary.org/obo/GO_0042418 GO:0042413 biolink:BiologicalProcess carnitine catabolic process The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. go-plus.json carnitine catabolism|vitamin Bt catabolism|carnitine degradation|vitamin Bt catabolic process|carnitine breakdown http://purl.obolibrary.org/obo/GO_0042413 GO:0042412 biolink:BiologicalProcess taurine biosynthetic process The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. go-plus.json taurine biosynthesis|taurine anabolism|taurine synthesis|taurine formation http://purl.obolibrary.org/obo/GO_0042412 GO:0042415 biolink:BiologicalProcess norepinephrine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. go-plus.json noradrenaline metabolism|noradrenaline metabolic process|levarterenol metabolism|norepinephrine metabolism|levarterenol metabolic process http://purl.obolibrary.org/obo/GO_0042415 GO:0042414 biolink:BiologicalProcess epinephrine metabolic process The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. go-plus.json epinephrine metabolism|adrenaline metabolism|adrenaline metabolic process http://purl.obolibrary.org/obo/GO_0042414 CHEBI:79246 biolink:ChemicalSubstance 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_79246 CHEBI:21949 biolink:ChemicalSubstance O-butanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21949 chebi_ph7_3 PO:0006204 biolink:OntologyClass sporocyte A native plant cell (PO:0025606) which is diploid (2n), and undergoes meiosis (GO:0007126) to produce four haploid (1n) plant spores (PO:0025017). go-plus.json 胞子母細胞 (Japanese, exact)|esporocito (Spanish, exact)|meiocyte (exact)|spore mother cell (exact) http://purl.obolibrary.org/obo/PO_0006204 GO:0042420 biolink:BiologicalProcess dopamine catabolic process The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. go-plus.json dopamine catabolism|dopamine degradation|dopamine breakdown http://purl.obolibrary.org/obo/GO_0042420 GO:0042422 biolink:BiologicalProcess norepinephrine catabolic process The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. Wikipedia:Norepinephrine#Degradation go-plus.json norepinephrine catabolism|noradrenaline catabolism|levarterenol catabolic process|levarterenol catabolism|norepinephrine degradation|noradrenaline catabolic process|norepinephrine breakdown http://purl.obolibrary.org/obo/GO_0042422 GO:0042421 biolink:BiologicalProcess norepinephrine biosynthetic process The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. go-plus.json norepinephrine biosynthesis|norepinephrine anabolism|noradrenaline biosynthesis|noradrenaline biosynthetic process|norepinephrine synthesis|norepinephrine formation|levarterenol biosynthesis|levarterenol biosynthetic process http://purl.obolibrary.org/obo/GO_0042421 GO:0042428 biolink:BiologicalProcess serotonin metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. go-plus.json serotonin metabolism http://purl.obolibrary.org/obo/GO_0042428 GO:0042427 biolink:BiologicalProcess serotonin biosynthetic process The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. Wikipedia:Serotonin go-plus.json serotonin biosynthesis|serotonin anabolism|serotonin synthesis|serotonin formation http://purl.obolibrary.org/obo/GO_0042427 GO:0042429 biolink:BiologicalProcess serotonin catabolic process The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. go-plus.json serotonin breakdown|serotonin catabolism|serotonin degradation http://purl.obolibrary.org/obo/GO_0042429 GO:0042424 biolink:BiologicalProcess catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. go-plus.json catecholamine breakdown|catecholamine catabolism|catecholamine degradation http://purl.obolibrary.org/obo/GO_0042424 GO:0042423 biolink:BiologicalProcess catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. Wikipedia:Catecholamines go-plus.json catecholamine anabolism|catecholamine synthesis|catecholamine formation|catecholamine biosynthesis http://purl.obolibrary.org/obo/GO_0042423 GO:0042426 biolink:BiologicalProcess choline catabolic process The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. go-plus.json choline degradation|choline breakdown|choline catabolism http://purl.obolibrary.org/obo/GO_0042426 GO:0042425 biolink:BiologicalProcess choline biosynthetic process The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. MetaCyc:PWY-4762 go-plus.json choline anabolism|choline synthesis|choline formation|choline biosynthesis http://purl.obolibrary.org/obo/GO_0042425 PO:0006210 biolink:OntologyClass protoderm A portion of meristem tissue (PO:0009013) that is the outer layer of an apical meristem (PO:0020144), or the outer layer of a plant embryo proper (PO:0000001), and gives rise to a portion of epidermis (PO:0005679). go-plus.json protodermis (Spanish, exact)|dermatogen cell (related)|前表皮、原表皮 (Japanese, exact)|portion of protoderm tissue (exact) http://purl.obolibrary.org/obo/PO_0006210 CHEBI:21911 biolink:ChemicalSubstance N(alpha)-methyl-L-histidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_21911 NCBITaxon:451442 biolink:OrganismalEntity Rhizophydiales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_451442 GO:0042431 biolink:BiologicalProcess indole metabolic process The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). go-plus.json indole metabolism http://purl.obolibrary.org/obo/GO_0042431 GO:0042430 biolink:BiologicalProcess indole-containing compound metabolic process The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. go-plus.json indole derivative metabolism|ketole metabolic process|indole-containing compound metabolism|indole and derivative metabolic process|indole derivative metabolic process|indole and derivative metabolism|ketole metabolism http://purl.obolibrary.org/obo/GO_0042430 GO:0042433 biolink:BiologicalProcess indole catabolic process The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). go-plus.json indole degradation|indole breakdown|indole catabolism http://purl.obolibrary.org/obo/GO_0042433 GO:0042432 biolink:BiologicalProcess indole biosynthetic process The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). go-plus.json indole biosynthesis|indole anabolism|indole synthesis|indole formation http://purl.obolibrary.org/obo/GO_0042432 GO:0042439 biolink:BiologicalProcess ethanolamine-containing compound metabolic process The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it. go-plus.json ethanolamine and derivative metabolism|ethanolamine-containing compound metabolism|ethanolamine and derivative metabolic process http://purl.obolibrary.org/obo/GO_0042439 GO:0042438 biolink:BiologicalProcess melanin biosynthetic process The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. go-plus.json melanin formation|melanin biosynthesis|melanin anabolism|melanin synthesis http://purl.obolibrary.org/obo/GO_0042438 GO:0042435 biolink:BiologicalProcess indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. go-plus.json indole-containing compound biosynthesis|indole-containing compound anabolism|indole derivative biosynthesis|indole derivative biosynthetic process|indole-containing compound synthesis|indole-containing compound formation http://purl.obolibrary.org/obo/GO_0042435 GO:0042434 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042434 GO:0042437 biolink:BiologicalProcess indoleacetic acid catabolic process The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants. go-plus.json indole acetic acid catabolic process|indole acetic acid catabolism|indoleacetic acid degradation|indoleacetic acid breakdown|IAA catabolic process|indoleacetic acid catabolism http://purl.obolibrary.org/obo/GO_0042437 GO:0042436 biolink:BiologicalProcess indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. go-plus.json indole-containing compound catabolism|indole derivative catabolism|indole-containing compound degradation|indole derivative catabolic process|indole-containing compound breakdown http://purl.obolibrary.org/obo/GO_0042436 GO:0042442 biolink:BiologicalProcess melatonin catabolic process The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). go-plus.json melatonin catabolism|melatonin degradation|melatonin breakdown http://purl.obolibrary.org/obo/GO_0042442 GO:0042441 biolink:BiologicalProcess eye pigment metabolic process The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye. go-plus.json eye pigment metabolism http://purl.obolibrary.org/obo/GO_0042441 GO:0042444 biolink:BiologicalProcess phenylethylamine biosynthetic process The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds. go-plus.json phenylethylamine anabolism|phenylethylamine synthesis|phenylethylamine biosynthesis|phenylethylamine formation http://purl.obolibrary.org/obo/GO_0042444 GO:0042443 biolink:BiologicalProcess phenylethylamine metabolic process The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds. go-plus.json phenylethylamine metabolism http://purl.obolibrary.org/obo/GO_0042443 GO:0042440 biolink:BiologicalProcess pigment metabolic process The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin. go-plus.json pigment metabolism http://purl.obolibrary.org/obo/GO_0042440 goslim_pir GO:0042449 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042449 GO:0042446 biolink:BiologicalProcess hormone biosynthetic process The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. go-plus.json hormone anabolism|hormone synthesis|hormone formation|hormone biosynthesis http://purl.obolibrary.org/obo/GO_0042446 CHEBI:79276 biolink:ChemicalSubstance 1-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79276 GO:0042445 biolink:BiologicalProcess hormone metabolic process The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. go-plus.json hormone metabolism http://purl.obolibrary.org/obo/GO_0042445 goslim_pir CHEBI:221278 biolink:ChemicalSubstance (R)-nipecotic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_221278 GO:0042448 biolink:BiologicalProcess progesterone metabolic process The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. go-plus.json progesterone metabolism http://purl.obolibrary.org/obo/GO_0042448 CHEBI:79274 biolink:ChemicalSubstance 1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79274 GO:0042447 biolink:BiologicalProcess hormone catabolic process The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. go-plus.json hormone breakdown|hormone catabolism|hormone degradation http://purl.obolibrary.org/obo/GO_0042447 CHEBI:79277 biolink:ChemicalSubstance 1-palmityl-2-acetyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79277 PR:000016156 biolink:Protein telethonin A protein that is a translation product of the human TCAP gene or a 1:1 ortholog thereof. go-plus.json TCAP|titin cap protein http://purl.obolibrary.org/obo/PR_000016156 GO:0042453 biolink:BiologicalProcess deoxyguanosine metabolic process The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose. go-plus.json deoxyguanosine metabolism http://purl.obolibrary.org/obo/GO_0042453 GO:0042452 biolink:BiologicalProcess deoxyguanosine biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose. go-plus.json deoxyguanosine anabolism|deoxyguanosine synthesis|deoxyguanosine formation|deoxyguanosine biosynthesis http://purl.obolibrary.org/obo/GO_0042452 GO:0042455 biolink:BiologicalProcess ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json ribonucleoside anabolism|ribonucleoside synthesis|ribonucleoside formation|ribonucleoside biosynthesis http://purl.obolibrary.org/obo/GO_0042455 GO:0042454 biolink:BiologicalProcess ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json ribonucleoside degradation|ribonucleoside catabolism|ribonucleoside breakdown http://purl.obolibrary.org/obo/GO_0042454 GO:0042451 biolink:BiologicalProcess purine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json purine nucleoside formation|purine nucleoside biosynthesis|purine nucleoside anabolism|purine nucleoside synthesis http://purl.obolibrary.org/obo/GO_0042451 GO:0042450 biolink:BiologicalProcess arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine. go-plus.json arginine anabolism via ornithine|arginine synthesis via ornithine|arginine formation via ornithine http://purl.obolibrary.org/obo/GO_0042450 CHEBI:79283 biolink:ChemicalSubstance 1-hexadecyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79283 CHEBI:79280 biolink:ChemicalSubstance 1-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79280 GO:0042457 biolink:BiologicalProcess ethylene catabolic process The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. go-plus.json ethylene breakdown|ethene catabolism|ethene catabolic process|ethylene catabolism|ethylene degradation http://purl.obolibrary.org/obo/GO_0042457 GO:0042456 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042456 GO:0042459 biolink:BiologicalProcess octopine catabolic process to proline The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline. MetaCyc:OCTOPINEDEG-PWY go-plus.json octopine breakdown to proline|octopine degradation to proline http://purl.obolibrary.org/obo/GO_0042459 GO:0042458 biolink:BiologicalProcess nopaline catabolic process to proline The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline. MetaCyc:NOPALINEDEG-PWY go-plus.json nopaline degradation to proline|nopaline breakdown to proline http://purl.obolibrary.org/obo/GO_0042458 CHEBI:79284 biolink:ChemicalSubstance trehalulose go-plus.json http://purl.obolibrary.org/obo/CHEBI_79284 chebi_ph7_3 CHEBI:79289 biolink:ChemicalSubstance N(5)-phenyl-L-glutamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79289 GO:0042464 biolink:BiologicalProcess dosage compensation by hypoactivation of X chromosome Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans. go-plus.json http://purl.obolibrary.org/obo/GO_0042464 GO:0042463 biolink:BiologicalProcess ocellus photoreceptor cell development Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus. go-plus.json non-eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042463 GO:0042466 biolink:BiologicalProcess chemokinesis A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis). Wikipedia:Chemokinesis go-plus.json http://purl.obolibrary.org/obo/GO_0042466 GO:0042465 biolink:BiologicalProcess kinesis The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus. Wikipedia:Kinesis go-plus.json http://purl.obolibrary.org/obo/GO_0042465 GO:0042460 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042460 GO:0042462 biolink:BiologicalProcess eye photoreceptor cell development Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. go-plus.json http://purl.obolibrary.org/obo/GO_0042462 GO:0042461 biolink:BiologicalProcess photoreceptor cell development Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. go-plus.json photoreceptor morphogenesis http://purl.obolibrary.org/obo/GO_0042461 CHEBI:79293 biolink:ChemicalSubstance 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_79293 GO:0042468 biolink:BiologicalProcess klinokinesis The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered. go-plus.json http://purl.obolibrary.org/obo/GO_0042468 GO:0042467 biolink:BiologicalProcess orthokinesis The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased. go-plus.json http://purl.obolibrary.org/obo/GO_0042467 CHEBI:79297 biolink:ChemicalSubstance 2-deoxy-alpha-L-fucosylaclacinomycin S go-plus.json http://purl.obolibrary.org/obo/CHEBI_79297 GO:0042469 biolink:MolecularActivity versicolorin reductase activity Catalysis of the reduction of versicolorin A to sterigmatocystin. go-plus.json http://purl.obolibrary.org/obo/GO_0042469 CHEBI:137396 biolink:ChemicalSubstance 5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137396 CHEBI:137395 biolink:ChemicalSubstance pyridinium-3,5-biscarboxylic acid mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_137395 CHEBI:137399 biolink:ChemicalSubstance Ni(II)-pyridinium-3,5-bisthiocarboxylic acid mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_137399 CHEBI:137398 biolink:ChemicalSubstance pyridinium-3,5-bisthiocarboxylic acid mononucleotide go-plus.json http://purl.obolibrary.org/obo/CHEBI_137398 CHEBI:137397 biolink:ChemicalSubstance 1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137397 GO:0042475 biolink:BiologicalProcess odontogenesis of dentin-containing tooth The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. go-plus.json odontogeny|odontogenesis of dentine-containing teeth|odontogenesis of dentine-containing tooth|odontosis|tooth development http://purl.obolibrary.org/obo/GO_0042475 GO:0042474 biolink:BiologicalProcess middle ear morphogenesis The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). go-plus.json http://purl.obolibrary.org/obo/GO_0042474 GO:0042477 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042477 GO:0042476 biolink:BiologicalProcess odontogenesis The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. Wikipedia:Odontogenesis go-plus.json odontosis|tooth morphogenesis|tooth development|odontogenesis of calcareous or chitinous tooth|odontogeny http://purl.obolibrary.org/obo/GO_0042476 GO:0042471 biolink:BiologicalProcess ear morphogenesis The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. go-plus.json hearing organ morphogenesis http://purl.obolibrary.org/obo/GO_0042471 GO:0042470 biolink:CellularComponent melanosome A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. Wikipedia:Melanosome go-plus.json http://purl.obolibrary.org/obo/GO_0042470 GO:0042473 biolink:BiologicalProcess outer ear morphogenesis The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. go-plus.json http://purl.obolibrary.org/obo/GO_0042473 GO:0042472 biolink:BiologicalProcess inner ear morphogenesis The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. go-plus.json http://purl.obolibrary.org/obo/GO_0042472 GO:0042479 biolink:BiologicalProcess positive regulation of eye photoreceptor cell development Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. go-plus.json upregulation of eye photoreceptor cell development|stimulation of eye photoreceptor cell development|up-regulation of eye photoreceptor cell development|activation of eye photoreceptor cell development|positive regulation of eye photoreceptor development|up regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0042479 GO:0042478 biolink:BiologicalProcess regulation of eye photoreceptor cell development Any process that modulates the frequency, rate or extent of eye photoreceptor development. go-plus.json regulation of eye photoreceptor development http://purl.obolibrary.org/obo/GO_0042478 CHEBI:80291 biolink:ChemicalSubstance aliphatic nitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_80291 chebi_ph7_3 CHEBI:45863 biolink:ChemicalSubstance paclitaxel go-plus.json http://purl.obolibrary.org/obo/CHEBI_45863 chebi_ph7_3 CHEBI:70829 biolink:ChemicalSubstance 15-methylhexadecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70829 chebi_ph7_3 CHEBI:70828 biolink:ChemicalSubstance 3-dehydro-15-methylhexadecasphinganine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70828 chebi_ph7_3 CHEBI:70827 biolink:ChemicalSubstance isopentadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70827 chebi_ph7_3 UBERON:0006440 biolink:AnatomicalEntity os clitoris The ossified region of endochondral and membranous bone located in the clitoris of most mammals except humans; it is homologous to the penile bone (aka as baculum, penis bone or os penis) in male mammals go-plus.json clitoris bone|clitoral bone|os clitoridis|baubellum http://purl.obolibrary.org/obo/UBERON_0006440 CHEBI:70826 biolink:ChemicalSubstance isopentadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_70826 chebi_ph7_3 CHEBI:45869 biolink:ChemicalSubstance estriol 3-O-(beta-D-glucuronide) go-plus.json http://purl.obolibrary.org/obo/CHEBI_45869 CHEBI:45868 biolink:ChemicalSubstance dTDP-4-dehydro-beta-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_45868 NCBITaxon:186634 biolink:OrganismalEntity Otomorpha go-plus.json Otocephala|Ostarioclupeomorpha http://purl.obolibrary.org/obo/NCBITaxon_186634 CHEBI:70820 biolink:ChemicalSubstance cob(II)yrinic acid c monoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_70820 UBERON:0006444 biolink:AnatomicalEntity annulus fibrosus A ring of fibrous or fibrocartilaginous tissue (as of an intervertebral disk or surrounding an orifice of the heart). go-plus.json fibrocartilaginous ring|anulus|anulus fibrosus|fibrous ring 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12,13-epoxy-18-hydroxy-(9Z)-octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137469 chebi_ph7_3 CHEBI:137467 biolink:ChemicalSubstance 9,10-epoxy-18-hydroxy-(12Z)-octadecenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137467 chebi_ph7_3 CHEBI:137461 biolink:ChemicalSubstance (9S,10R)-epoxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137461 chebi_ph7_3 CHEBI:137460 biolink:ChemicalSubstance (9R,10S)-9,10-epoxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137460 chebi_ph7_3 CHEBI:137463 biolink:ChemicalSubstance 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137463 CHEBI:137449 biolink:ChemicalSubstance phosphatidic acid 30:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137449 CHEBI:70781 biolink:ChemicalSubstance PPAR modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_70781 CHEBI:70780 biolink:ChemicalSubstance 1-deoxy-11-oxopentalenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_70780 chebi_ph7_3 GO:0042521 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042521 GO:0042520 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042520 GO:0042527 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042527 GO:0042526 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042526 GO:0042529 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042529 GO:0042528 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042528 GO:0042523 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042523 GO:0042522 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042522 CHEBI:79110 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79110 GO:0042525 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042525 GO:0042524 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042524 CHEBI:70789 biolink:ChemicalSubstance pentalenolactone F(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70789 chebi_ph7_3 CHEBI:70788 biolink:ChemicalSubstance pentalenolactone E(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70788 chebi_ph7_3 CHEBI:70787 biolink:ChemicalSubstance pentalenolactone D(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70787 chebi_ph7_3 CHEBI:79113 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79113 CHEBI:70786 biolink:ChemicalSubstance C30 botryococcene go-plus.json http://purl.obolibrary.org/obo/CHEBI_70786 chebi_ph7_3 CHEBI:70785 biolink:ChemicalSubstance CDP-3,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70785 chebi_ph7_3 CHEBI:21815 biolink:ChemicalSubstance N2-acyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21815 CHEBI:70784 biolink:ChemicalSubstance CDP-alpha-D-abequose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70784 chebi_ph7_3 CHEBI:70783 biolink:ChemicalSubstance CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70783 chebi_ph7_3 CHEBI:70782 biolink:ChemicalSubstance PPARalpha agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_70782 CHEBI:21816 biolink:ChemicalSubstance N(2)-glutamino group go-plus.json http://purl.obolibrary.org/obo/CHEBI_21816 CHEBI:70792 biolink:ChemicalSubstance cobalt-precorrin-8(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70792 chebi_ph7_3 CHEBI:70791 biolink:ChemicalSubstance cobalt-precorrin-7(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70791 chebi_ph7_3 CHEBI:70790 biolink:ChemicalSubstance pentalenolactone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70790 chebi_ph7_3 GO:0150200 biolink:BiologicalProcess regulation of transport across blood-brain barrier Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0150200 GO:0042530 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042530 GO:0042532 biolink:BiologicalProcess negative regulation of tyrosine phosphorylation of STAT protein Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json down-regulation of tyrosine phosphorylation of Stat7 protein|negative regulation of tyrosine phosphorylation of Stat7 protein|down-regulation of tyrosine phosphorylation of Stat6 protein|inhibition of tyrosine phosphorylation of STAT protein|negative regulation of tyrosine phosphorylation of Stat6 protein|down-regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|down-regulation of tyrosine phosphorylation of Stat4 protein|negative regulation of tyrosine phosphorylation of Stat4 protein|down-regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of Stat1 protein|negative regulation of tyrosine phosphorylation of Stat1 protein|inhibition of tyrosine phosphorylation of Stat7 protein|inhibition of tyrosine phosphorylation of Stat6 protein|inhibition of tyrosine phosphorylation of Stat5 protein|inhibition of tyrosine phosphorylation of Stat4 protein|inhibition of tyrosine phosphorylation of Stat3 protein|inhibition of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of STAT protein|inhibition of tyrosine phosphorylation of Stat1 protein|down regulation of tyrosine phosphorylation of Stat7 protein|down regulation of tyrosine phosphorylation of Stat6 protein|down regulation of tyrosine phosphorylation of Stat5 protein|down regulation of tyrosine phosphorylation of Stat4 protein|downregulation of tyrosine phosphorylation of Stat7 protein|down regulation of tyrosine phosphorylation of Stat3 protein|down regulation of tyrosine phosphorylation of Stat2 protein|downregulation of tyrosine phosphorylation of Stat6 protein|downregulation of tyrosine phosphorylation of Stat5 protein|down regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat4 protein|downregulation of tyrosine phosphorylation of Stat3 protein|downregulation of tyrosine phosphorylation of STAT protein|downregulation of tyrosine phosphorylation of Stat2 protein|downregulation of tyrosine phosphorylation of Stat1 protein|down regulation of tyrosine phosphorylation of STAT protein http://purl.obolibrary.org/obo/GO_0042532 GO:0042531 biolink:BiologicalProcess positive regulation of tyrosine phosphorylation of STAT protein Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json activation of tyrosine phosphorylation of Stat7 protein|positive regulation of tyrosine phosphorylation of Stat2 protein|activation of tyrosine phosphorylation of Stat6 protein|positive regulation of tyrosine phosphorylation of Stat1 protein|activation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of Stat4 protein|stimulation of tyrosine phosphorylation of Stat7 protein|stimulation of tyrosine phosphorylation of Stat6 protein|activation of tyrosine phosphorylation of Stat3 protein|activation of tyrosine phosphorylation of Stat2 protein|stimulation of tyrosine phosphorylation of Stat5 protein|stimulation of tyrosine phosphorylation of Stat4 protein|activation of tyrosine phosphorylation of Stat1 protein|up-regulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat6 protein|stimulation of tyrosine phosphorylation of Stat3 protein|stimulation of tyrosine phosphorylation of Stat2 protein|up-regulation of tyrosine phosphorylation of Stat5 protein|stimulation of tyrosine phosphorylation of STAT protein|stimulation of tyrosine phosphorylation of Stat1 protein|up-regulation of tyrosine phosphorylation of Stat4 protein|up-regulation of tyrosine phosphorylation of Stat3 protein|up-regulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of STAT protein|up-regulation of tyrosine phosphorylation of Stat2 protein|up-regulation of tyrosine phosphorylation of Stat1 protein|upregulation of tyrosine phosphorylation of Stat7 protein|upregulation of tyrosine phosphorylation of Stat6 protein|upregulation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of Stat4 protein|upregulation of tyrosine phosphorylation of Stat3 protein|upregulation of tyrosine phosphorylation of Stat2 protein|upregulation of tyrosine phosphorylation of Stat1 protein|up regulation of tyrosine phosphorylation of STAT protein|up regulation of tyrosine phosphorylation of Stat7 protein|up regulation of tyrosine phosphorylation of Stat6 protein|positive regulation of tyrosine phosphorylation of Stat7 protein|up regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat4 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|up regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|up regulation of tyrosine phosphorylation of Stat2 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|up regulation of tyrosine phosphorylation of Stat1 protein http://purl.obolibrary.org/obo/GO_0042531 GO:0042538 biolink:BiologicalProcess hyperosmotic salinity response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json response to hyperosmotic salt stress|salt tolerance http://purl.obolibrary.org/obo/GO_0042538 GO:0042537 biolink:BiologicalProcess benzene-containing compound metabolic process The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives. go-plus.json benzene-containing compound metabolism|benzene and derivative metabolic process|benzene and derivative metabolism http://purl.obolibrary.org/obo/GO_0042537 GO:0042539 biolink:BiologicalProcess hypotonic salinity response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json response to hypotonic salt stress http://purl.obolibrary.org/obo/GO_0042539 GO:0042534 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042534 CHEBI:79122 biolink:ChemicalSubstance 2,7-dihydroxy-5-methyl-1-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79122 GO:0042533 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042533 GO:0042536 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042536 GO:0150202 biolink:BiologicalProcess negative regulation of transport across blood-brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0150202 GO:0150201 biolink:BiologicalProcess positive regulation of transport across blood-brain barrier Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier. go-plus.json http://purl.obolibrary.org/obo/GO_0150201 GO:0042535 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042535 PO:0006341 biolink:OntologyClass primary shoot system A shoot system (PO:0009006) that develops from an embryo shoot apical meristem (PO:0006362). go-plus.json 一次分げつ系 (Japanese, exact)|main stalk (related)|sistema axilar primario (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006341 CHEBI:70799 biolink:ChemicalSubstance CDP-alpha-D-abequose go-plus.json http://purl.obolibrary.org/obo/CHEBI_70799 CHEBI:79125 biolink:ChemicalSubstance 2-hydroxy-7-methoxy-5-methyl-1-naphthoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79125 CHEBI:70798 biolink:ChemicalSubstance 15-methylhexadecasphing-4-enine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70798 CHEBI:70797 biolink:ChemicalSubstance 1-deoxy-11-oxopentalenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70797 CHEBI:70796 biolink:ChemicalSubstance 1-deoxy-11beta-hydroxypentalenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70796 CHEBI:21826 biolink:ChemicalSubstance N(3')-acetylgentamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_21826 PO:0006343 biolink:OntologyClass axillary shoot system A shoot-borne shoot system (PO:0004545) that develops from an axillary bud (PO:0004709). go-plus.json 腋苗条系 (Japanese, exact)|sistema axilar del epiblasto (epiblastema) (Spanish, exact)|axillary branch (related)|Musa sucker (narrow) http://purl.obolibrary.org/obo/PO_0006343 CHEBI:70793 biolink:ChemicalSubstance cob(II)yrinate c monoamide(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70793 chebi_ph7_3 GO:0042541 biolink:BiologicalProcess hemoglobin biosynthetic process The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. go-plus.json hemoglobin anabolism|hemoglobin biosynthesis|hemoglobin synthesis|hemoglobin formation|haemoglobin biosynthetic process|haemoglobin biosynthesis http://purl.obolibrary.org/obo/GO_0042541 GO:0042540 biolink:BiologicalProcess hemoglobin catabolic process The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids. go-plus.json hemoglobin catabolism|hemoglobin hydrolysis|haemoglobin catabolic process|haemoglobin catabolism|hemoglobin degradation|hemoglobin breakdown|haemoglobin hydrolysis http://purl.obolibrary.org/obo/GO_0042540 GO:0042543 biolink:BiologicalProcess protein N-linked glycosylation via arginine The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine. RESID:AA0327 go-plus.json protein amino acid N-linked glycosylation via arginine http://purl.obolibrary.org/obo/GO_0042543 GO:0042542 biolink:BiologicalProcess response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0042542 GO:0042549 biolink:BiologicalProcess photosystem II stabilization The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0042549 GO:0042548 biolink:BiologicalProcess regulation of photosynthesis, light reaction Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0042548 GO:0042545 biolink:BiologicalProcess cell wall modification The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly. go-plus.json http://purl.obolibrary.org/obo/GO_0042545 GO:0042544 biolink:BiologicalProcess melibiose biosynthetic process The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. go-plus.json melibiose synthesis|melibiose formation|melibiose biosynthesis|melibiose anabolism http://purl.obolibrary.org/obo/GO_0042544 GO:0042547 biolink:BiologicalProcess cell wall modification involved in multidimensional cell growth The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth. go-plus.json cell wall modification during multidimensional cell growth|cell wall modification during cell expansion http://purl.obolibrary.org/obo/GO_0042547 GO:0042546 biolink:BiologicalProcess cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. go-plus.json cell wall assembly http://purl.obolibrary.org/obo/GO_0042546 GO:0042552 biolink:BiologicalProcess myelination The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. Wikipedia:Myelin go-plus.json myelinogenesis http://purl.obolibrary.org/obo/GO_0042552 GO:0042551 biolink:BiologicalProcess neuron maturation A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0042551 GO:0042554 biolink:BiologicalProcess superoxide anion generation The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways. go-plus.json superoxide release http://purl.obolibrary.org/obo/GO_0042554 GO:0042553 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042553 GO:0042550 biolink:BiologicalProcess photosystem I stabilization The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0042550 GO:0042559 biolink:BiologicalProcess pteridine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. go-plus.json pteridine-containing compound biosynthesis|pteridine-containing compound anabolism|pterin biosynthesis|pterin biosynthetic process|pteridine-containing compound synthesis|pteridine-containing compound formation|pteridine and derivative biosynthesis|pteridine and derivative biosynthetic process http://purl.obolibrary.org/obo/GO_0042559 goslim_pombe GO:0042556 biolink:MolecularActivity eukaryotic elongation factor-2 kinase regulator activity Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase. go-plus.json eEF-2 kinase regulator http://purl.obolibrary.org/obo/GO_0042556 GO:0042555 biolink:CellularComponent MCM complex A hexameric protein complex required for the initiation and regulation of DNA replication. go-plus.json mini-chromosome maintenance complex http://purl.obolibrary.org/obo/GO_0042555 GO:0042558 biolink:BiologicalProcess pteridine-containing compound metabolic process The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. go-plus.json pteridine-containing compound metabolism|pteridine and derivative metabolic process|pterin metabolic process|pterin metabolism|pteridine and derivative metabolism http://purl.obolibrary.org/obo/GO_0042558 GO:0042557 biolink:MolecularActivity eukaryotic elongation factor-2 kinase activator activity Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase. go-plus.json eEF-2 kinase activator http://purl.obolibrary.org/obo/GO_0042557 CHEBI:21806 biolink:ChemicalSubstance N(2),N(5)-diacyl-L-ornithine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21806 CHEBI:21805 biolink:ChemicalSubstance N(2')-acetylgentamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_21805 GO:0042563 biolink:CellularComponent obsolete importin alpha-subunit nuclear export complex OBSOLETE. A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to transport the importin alpha-subunit out of the nucleus through the nuclear pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042563 GO:0042562 biolink:MolecularActivity hormone binding Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0042562 goslim_chembl|goslim_pir GO:0042565 biolink:CellularComponent RNA nuclear export complex A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042565 GO:0042564 biolink:CellularComponent NLS-dependent protein nuclear import complex A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore. go-plus.json http://purl.obolibrary.org/obo/GO_0042564 GO:0042561 biolink:MolecularActivity alpha-amyrin synthase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin. MetaCyc:RXN-8434 go-plus.json http://purl.obolibrary.org/obo/GO_0042561 GO:0042560 biolink:BiologicalProcess pteridine-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. go-plus.json pteridine and derivative catabolism|pteridine-containing compound catabolism|pteridine-containing compound degradation|pteridine-containing compound breakdown|pterin catabolism|pterin catabolic process|pteridine and derivative catabolic process http://purl.obolibrary.org/obo/GO_0042560 GO:0042567 biolink:CellularComponent insulin-like growth factor ternary complex A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development. go-plus.json IGF ternary complex http://purl.obolibrary.org/obo/GO_0042567 GO:0042566 biolink:CellularComponent hydrogenosome A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation. Wikipedia:Hydrogenosome go-plus.json http://purl.obolibrary.org/obo/GO_0042566 goslim_pir GO:0042569 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042569 GO:0042568 biolink:CellularComponent insulin-like growth factor binary complex A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development. go-plus.json IGF binary complex http://purl.obolibrary.org/obo/GO_0042568 GO:0042574 biolink:BiologicalProcess retinal metabolic process The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A. go-plus.json retinal metabolism|retinaldehyde metabolic process|retinaldehyde metabolism http://purl.obolibrary.org/obo/GO_0042574 GO:0042573 biolink:BiologicalProcess retinoic acid metabolic process The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A. go-plus.json vitamin A1 acid metabolic process|retinoic acid metabolism|vitamin A1 acid metabolism http://purl.obolibrary.org/obo/GO_0042573 GO:0042576 biolink:MolecularActivity obsolete aspartyl aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate. go-plus.json aspartyl aminopeptidase activity http://purl.obolibrary.org/obo/GO_0042576 GO:0042575 biolink:CellularComponent DNA polymerase complex A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0042575 goslim_metagenomics|goslim_pir GO:0042570 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042570 GO:0042572 biolink:BiologicalProcess retinol metabolic process The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A. Wikipedia:Retinol go-plus.json vitamin A1 metabolic process|vitamin A1 alcohol metabolism|vitamin A1 alcohol metabolic process|vitamin A1 metabolism|retinol metabolism http://purl.obolibrary.org/obo/GO_0042572 GO:0042571 biolink:CellularComponent immunoglobulin complex, circulating An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component. Wikipedia:Antibody go-plus.json antibody http://purl.obolibrary.org/obo/GO_0042571 GO:0042578 biolink:MolecularActivity phosphoric ester hydrolase activity Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. go-plus.json http://purl.obolibrary.org/obo/GO_0042578 GO:0042577 biolink:MolecularActivity lipid phosphatase activity Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0042577 GO:0042579 biolink:CellularComponent microbody Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2). Wikipedia:Microbody go-plus.json http://purl.obolibrary.org/obo/GO_0042579 goslim_pir CHEBI:79169 biolink:ChemicalSubstance 15-hydroxypentadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79169 GO:0042585 biolink:CellularComponent germinal vesicle The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity. go-plus.json primary oocyte nucleus http://purl.obolibrary.org/obo/GO_0042585 GO:0042584 biolink:CellularComponent chromaffin granule membrane The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine. go-plus.json http://purl.obolibrary.org/obo/GO_0042584 GO:0042587 biolink:CellularComponent glycogen granule Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface. NIF_Subcellular:sao1081228141 go-plus.json glycogen particle http://purl.obolibrary.org/obo/GO_0042587 GO:0042586 biolink:MolecularActivity peptide deformylase activity Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide. EC:3.5.1.88|RHEA:24420|MetaCyc:3.5.1.88-RXN go-plus.json polypeptide deformylase activity|formyl-L-methionyl peptide amidohydrolase activity|PDF activity http://purl.obolibrary.org/obo/GO_0042586 GO:0042581 biolink:CellularComponent specific granule Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. Wikipedia:Specific_granule go-plus.json secondary granule http://purl.obolibrary.org/obo/GO_0042581 GO:0042580 biolink:CellularComponent mannosome A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0042580 GO:0042583 biolink:CellularComponent chromaffin granule Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine. go-plus.json http://purl.obolibrary.org/obo/GO_0042583 GO:0042582 biolink:CellularComponent azurophil granule Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. go-plus.json primary granule http://purl.obolibrary.org/obo/GO_0042582 CHEBI:79173 biolink:ChemicalSubstance dTDP-2-deoxy-beta-L-fucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_79173 CHEBI:79172 biolink:ChemicalSubstance 2-hydroxy-6-(2-oxidophenyl)-6-oxo-cis,cis-hexa-2,4-dienoate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79172 chebi_ph7_3 CHEBI:79171 biolink:ChemicalSubstance dTDP-beta-L-rhodosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79171 GO:0042589 biolink:CellularComponent zymogen granule membrane The lipid bilayer surrounding a zymogen granule. go-plus.json http://purl.obolibrary.org/obo/GO_0042589 CHEBI:79176 biolink:ChemicalSubstance aclacinomycin S go-plus.json http://purl.obolibrary.org/obo/CHEBI_79176 GO:0042588 biolink:CellularComponent zymogen granule A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0042588 CHEBI:79174 biolink:ChemicalSubstance 2,2',3-trihydroxydiphenyl ether(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79174 chebi_ph7_3 GO:0042590 biolink:BiologicalProcess antigen processing and presentation of exogenous peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. go-plus.json antigen presentation, exogenous antigen via MHC class I|cross-presentation|cross priming|cross presentation|antigen presentation, exogenous antigen via major histocompatibility complex class I|cross-priming|exogenous peptide antigen processing and presentation via MHC class I http://purl.obolibrary.org/obo/GO_0042590 GO:0042596 biolink:BiologicalProcess fear response The response of an organism to a perceived external threat. go-plus.json physiological fear response http://purl.obolibrary.org/obo/GO_0042596 GO:0042595 biolink:BiologicalProcess behavioral response to starvation Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment. go-plus.json behavioural response to starvation http://purl.obolibrary.org/obo/GO_0042595 GO:0042598 biolink:CellularComponent obsolete vesicular fraction OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized. go-plus.json vesicular fraction http://purl.obolibrary.org/obo/GO_0042598 GO:0042597 biolink:CellularComponent periplasmic space The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). go-plus.json periplasm http://purl.obolibrary.org/obo/GO_0042597 goslim_pir|goslim_metagenomics GO:0042592 biolink:BiologicalProcess homeostatic process Any biological process involved in the maintenance of an internal steady state. go-plus.json regulation of homeostatic process|activation of homeostatic process|positive regulation of homeostatic process|homeostasis|negative regulation of homeostatic process|inhibition of homeostatic process http://purl.obolibrary.org/obo/GO_0042592 goslim_generic|goslim_chembl|goslim_mouse|goslim_agr CHEBI:79191 biolink:ChemicalSubstance L-Cys(IAN) zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_79191 chebi_ph7_3 GO:0042591 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042591 GO:0042594 biolink:BiologicalProcess response to starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment. go-plus.json http://purl.obolibrary.org/obo/GO_0042594 goslim_yeast GO:0042593 biolink:BiologicalProcess glucose homeostasis Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0042593 CHEBI:79183 biolink:ChemicalSubstance 5,10-dihydro-9-dimethylallylphenazine-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79183 CHEBI:79182 biolink:ChemicalSubstance 18-hydroxyoctadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79182 CHEBI:79181 biolink:ChemicalSubstance 5,10-dihydrophenazine-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_79181 CHEBI:79188 biolink:ChemicalSubstance (3R)-3-ammonio-3-phenylpropanoyl-CoA(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79188 chebi_ph7_3 GO:0042599 biolink:CellularComponent lamellar body A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. NIF_Subcellular:sao1379604862 go-plus.json membrane-coating granule|keratinosome|lamellar granule|Odland body http://purl.obolibrary.org/obo/GO_0042599 CHEBI:79187 biolink:ChemicalSubstance pppGp(2'->5')A go-plus.json http://purl.obolibrary.org/obo/CHEBI_79187 CHEBI:79186 biolink:ChemicalSubstance 3'-N-debenzoyl-2'-deoxytaxol(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_79186 chebi_ph7_3 CHEBI:79185 biolink:ChemicalSubstance 4-O-dimethylallyl-L-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79185 PR:000016261 biolink:Protein serotransferrin A protein that is a translation product of the human TF gene or a 1:1 ortholog thereof. go-plus.json transferrin|Trf|beta-1 metal-binding globulin|siderophilin|TF http://purl.obolibrary.org/obo/PR_000016261 CHEBI:79189 biolink:ChemicalSubstance D-ribofuranose-2,5-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_79189 NCBITaxon:8976 biolink:OrganismalEntity Galliformes go-plus.json landfowls http://purl.obolibrary.org/obo/NCBITaxon_8976 CHEBI:45744 biolink:ChemicalSubstance N-acetyl-beta-neuraminic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45744 CHEBI:70709 biolink:ChemicalSubstance progesterone receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_70709 UBERON:0006563 biolink:AnatomicalEntity tunica media of pulmonary trunk Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0006563 UBERON:0006562 biolink:AnatomicalEntity pharynx The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. go-plus.json pharyngeal tube|anterior part of foregut http://purl.obolibrary.org/obo/UBERON_0006562 UBERON:0006561 biolink:AnatomicalEntity non-lymphatic part of lymphoid system An organ system subdivision that is the part of the lymphoid system that excludes the lymphatic vessels.. go-plus.json non-lymphatic lymphoid system http://purl.obolibrary.org/obo/UBERON_0006561 UBERON:0006569 biolink:AnatomicalEntity diencephalic nucleus A nucleus of brain that is part of a diencephalon. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006569 UBERON:0006568 biolink:AnatomicalEntity hypothalamic nucleus A nucleus of brain that is part of a hypothalamus. go-plus.json nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0006568 UBERON:0006567 biolink:AnatomicalEntity right ventricle myocardium A myocardium that is part of a right ventricle of a heart. go-plus.json myocardium of right ventricle|right ventricular myocardium http://purl.obolibrary.org/obo/UBERON_0006567 UBERON:0006566 biolink:AnatomicalEntity left ventricle myocardium A myocardium that is part of a left ventricle of a heart. go-plus.json myocardium of left ventricle|left ventricular myocardium http://purl.obolibrary.org/obo/UBERON_0006566 UBERON:0006565 biolink:AnatomicalEntity female urethral meatus A urethral meatus that is part of a female urethra[Automatically generated definition]. go-plus.json urethral meatus of clitoral urethra|distal urethral opening of female|external orifice of female urethra|female urethral meatus|external urethral orifice (female)|ostium urethrae externum (urethra feminina)|urethral opening of clitoral urethra http://purl.obolibrary.org/obo/UBERON_0006565 CHEBI:31107 biolink:ChemicalSubstance 3-amino-4,7-dihydroxycoumarin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31107 CHEBI:21787 biolink:ChemicalSubstance N-seryl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21787 UBERON:0006553 biolink:AnatomicalEntity renal duct A tube in the kidney that collect and transport urine. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006553 CHEBI:70716 biolink:ChemicalSubstance cis-tetradec-5-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70716 CHEBI:70712 biolink:ChemicalSubstance (5Z)-tetradecenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_70712 CHEBI:31104 biolink:ChemicalSubstance 3,5-dihydroxyphenylglyoxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31104 CHEBI:31103 biolink:ChemicalSubstance 3,5-dihydroxyphenylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_31103 UBERON:0006558 biolink:AnatomicalEntity lymphatic part of lymphoid system An organ system subdivision that is a network of vessels capable of removing accumulating protein and fluid from the interstitial space and returning it to the vascular space. In some species, this network is connected to the immune system via lymph nodes and lymphocyte-producing organs, with the whole being the lymphoid system. go-plus.json lymphatic system|lymporeticular system|lymphatic tree system http://purl.obolibrary.org/obo/UBERON_0006558 UBERON:0006555 biolink:AnatomicalEntity excretory tube A tube that is part of a excretory system. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006555 CHEBI:21752 biolink:ChemicalSubstance N-methyl-L-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21752 UBERON:0006542 biolink:AnatomicalEntity outer medulla outer stripe loop of Henle A loop of Henle that is part of a kidney outer medulla outer stripe. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006542 UBERON:0006541 biolink:AnatomicalEntity outer medulla inner stripe loop of Henle A loop of Henle that is part of a kidney outer medulla inner stripe. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006541 CHEBI:70728 biolink:ChemicalSubstance actin polymerisation inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_70728 CHEBI:70727 biolink:ChemicalSubstance topoisomerase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_70727 CHEBI:70726 biolink:ChemicalSubstance hesperadin go-plus.json http://purl.obolibrary.org/obo/CHEBI_70726 CHEBI:45725 biolink:ChemicalSubstance spermine(4+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_45725 chebi_ph7_3 CHEBI:70725 biolink:ChemicalSubstance adenosine A3 receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_70725 CHEBI:70724 biolink:ChemicalSubstance cell dedifferentiation agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_70724 CHEBI:70723 biolink:ChemicalSubstance reversine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70723 chebi_ph7_3 CHEBI:70722 biolink:ChemicalSubstance EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_70722 UBERON:0006544 biolink:AnatomicalEntity kidney vasculature A vasculature that is part of a kidney. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006544 CHEBI:21760 biolink:ChemicalSubstance N-methyl-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21760 CHEBI:21763 biolink:ChemicalSubstance N-methylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21763 UBERON:0006531 biolink:AnatomicalEntity oculomotor muscle The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006531 UBERON:0006530 biolink:AnatomicalEntity seminal fluid A substance formed from the secretion of one or more glands of the male genital tract in which sperm cells are suspended. go-plus.json seminal fluid|male genital secretion|male genital fluid|seminal plasma http://purl.obolibrary.org/obo/UBERON_0006530 CHEBI:45718 biolink:ChemicalSubstance 3,3,3-tetramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_45718 CHEBI:70738 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-mannosaminouronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70738 CHEBI:45713 biolink:ChemicalSubstance trans-resveratrol go-plus.json http://purl.obolibrary.org/obo/CHEBI_45713 chebi_ph7_3 UBERON:0006539 biolink:AnatomicalEntity mammary gland fluid/secretion A substance that is secreted by a mammary gland. The substance may differ depending on phase, with colostrum produced during pregancy/early lactation, and milk produced afterwards. go-plus.json lactiferous gland fluid|mammary gland secreted fluid|mammary gland fluid|lactiferous gland secretion|secretion of mammary gland|mammary gland secretion http://purl.obolibrary.org/obo/UBERON_0006539 UBERON:0006538 biolink:AnatomicalEntity respiratory system fluid/secretion A portion of organism substance that secreted_by a respiratory system. go-plus.json respiratory system secretion|respiratory system fluid http://purl.obolibrary.org/obo/UBERON_0006538 CHEBI:21766 biolink:ChemicalSubstance N-methylglycines go-plus.json http://purl.obolibrary.org/obo/CHEBI_21766 UBERON:0006537 biolink:AnatomicalEntity female reproductive gland secretion A portion of organism substance that is secreted by a female reproductive gland. go-plus.json female reproductive system secretion|female reproductive system fluid/secretion|female reproductive system fluid http://purl.obolibrary.org/obo/UBERON_0006537 UBERON:0006536 biolink:AnatomicalEntity male reproductive gland secretion A portion of organism substance that is secreted by a male reproductive gland. go-plus.json male reproductive system fluid/secretion|male reproductive system secretion|male reproductive system fluid http://purl.obolibrary.org/obo/UBERON_0006536 CHEBI:70731 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-mannosaminouronate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70731 chebi_ph7_3 UBERON:0006535 biolink:AnatomicalEntity skin secretion A portion of organism substance that secreted_by a zone of skin. go-plus.json skin fluid/secretion|skin substance|skin fluid http://purl.obolibrary.org/obo/UBERON_0006535 UBERON:0006534 biolink:AnatomicalEntity renal convoluted tubule Any region of a nephron tubule that is convoluted. Examples: distal convoluted tubule, proximal convoluted tuble. go-plus.json convoluted tubule|kidney convoluted tubule http://purl.obolibrary.org/obo/UBERON_0006534 UBERON:0006533 biolink:AnatomicalEntity rectus extraocular muscle go-plus.json http://purl.obolibrary.org/obo/UBERON_0006533 UBERON:0006532 biolink:AnatomicalEntity oblique extraocular muscle go-plus.json http://purl.obolibrary.org/obo/UBERON_0006532 CHEBI:21732 biolink:ChemicalSubstance N-glycyl-glycosylphosphatidylinositolethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21732 CHEBI:21731 biolink:ChemicalSubstance N-glycosyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_21731 CHEBI:70749 biolink:ChemicalSubstance O-hexanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70749 chebi_ph7_3 CHEBI:70744 biolink:ChemicalSubstance Gly-Pro go-plus.json http://purl.obolibrary.org/obo/CHEBI_70744 UBERON:0006596 biolink:AnatomicalEntity presumptive blood go-plus.json future blood http://purl.obolibrary.org/obo/UBERON_0006596 UBERON:0006595 biolink:AnatomicalEntity presumptive endoderm Presumptive structure of the blastula that will develop into endoderm. go-plus.json http://purl.obolibrary.org/obo/UBERON_0006595 CHEBI:70758 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alaninate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70758 chebi_ph7_3 CHEBI:70757 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70757 chebi_ph7_3 CHEBI:21745 biolink:ChemicalSubstance N-(long-chain-fatty-acyl)-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21745 CHEBI:70755 biolink:ChemicalSubstance methyltelluronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70755 UBERON:0006599 biolink:AnatomicalEntity presumptive hypochord Tissue is fated to develop into the hypochord. go-plus.json future hypochord http://purl.obolibrary.org/obo/UBERON_0006599 UBERON:0006598 biolink:AnatomicalEntity presumptive structure Portion of embryonic tissue determined by fate mapping to become a structure. go-plus.json future structure|presumptive structures http://purl.obolibrary.org/obo/UBERON_0006598 GO:0042505 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042505 UBERON:0006585 biolink:AnatomicalEntity vestibular organ An organ that is part of a vestibular system. go-plus.json balance organ http://purl.obolibrary.org/obo/UBERON_0006585 GO:0042504 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042504 GO:0042507 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042507 GO:0042506 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042506 GO:0042501 biolink:BiologicalProcess serine phosphorylation of STAT protein The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json serine phosphorylation of STAT3 protein http://purl.obolibrary.org/obo/GO_0042501 GO:0042500 biolink:MolecularActivity aspartic endopeptidase activity, intramembrane cleaving Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane. Reactome:R-HSA-8863101|EC:3.4.23.- go-plus.json http://purl.obolibrary.org/obo/GO_0042500 GO:0042503 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042503 CHEBI:70768 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70768 GO:0042502 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042502 CHEBI:70765 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70765 CHEBI:70764 biolink:ChemicalSubstance tritrans,heptacis-undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_70764 CHEBI:70763 biolink:ChemicalSubstance tritrans,heptacis-undecaprenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70763 chebi_ph7_3 GO:0042509 biolink:BiologicalProcess regulation of tyrosine phosphorylation of STAT protein Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json regulation of tyrosine phosphorylation of Stat7 protein|regulation of tyrosine phosphorylation of Stat6 protein|regulation of tyrosine phosphorylation of Stat5 protein|regulation of tyrosine phosphorylation of Stat4 protein|regulation of tyrosine phosphorylation of Stat3 protein|regulation of tyrosine phosphorylation of Stat2 protein|regulation of tyrosine phosphorylation of Stat1 protein http://purl.obolibrary.org/obo/GO_0042509 GO:0042508 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042508 CHEBI:70760 biolink:ChemicalSubstance all-trans-retinyl oleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_70760 chebi_ph7_3 CHEBI:70770 biolink:ChemicalSubstance Aurora kinase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_70770 CHEBI:79109 biolink:ChemicalSubstance 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79109 GO:0042510 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042510 GO:0042516 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042516 UBERON:0006574 biolink:AnatomicalEntity pectinate line The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line: go-plus.json linea pectinata canalis analis|pectinate line of anal canal|site of anal membrane|dentate line|Hilton's 'white line'|linea anocutanea|recto-anal junction http://purl.obolibrary.org/obo/UBERON_0006574 GO:0042515 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042515 GO:0042518 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042518 GO:0042517 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042517 UBERON:0006571 biolink:AnatomicalEntity trabecula carnea of left ventricle A trabecula carnea that is part of a heart left ventricle. go-plus.json trabeculae carneae (ventriculus sinister) http://purl.obolibrary.org/obo/UBERON_0006571 GO:0042512 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042512 GO:0042511 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042511 UBERON:0006570 biolink:AnatomicalEntity trabecula carnea of right ventricle A trabecula carnea that is part of a heart right ventricle. go-plus.json trabeculae carneae (ventriculus dexter) http://purl.obolibrary.org/obo/UBERON_0006570 GO:0042514 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042514 CHEBI:70779 biolink:ChemicalSubstance 1-deoxy-11beta-hydroxypentalenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_70779 chebi_ph7_3 GO:0042513 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042513 CHEBI:70778 biolink:ChemicalSubstance GW 7647 go-plus.json http://purl.obolibrary.org/obo/CHEBI_70778 CHEBI:79103 biolink:ChemicalSubstance 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79103 CHEBI:70776 biolink:ChemicalSubstance N-acyl-4-hydroxy-15-methylhexadecasphinganine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70776 chebi_ph7_3 CHEBI:79102 biolink:ChemicalSubstance 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_79102 CHEBI:70775 biolink:ChemicalSubstance N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70775 chebi_ph7_3 CHEBI:70774 biolink:ChemicalSubstance capsaicin receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_70774 GO:0042519 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0042519 CHEBI:70773 biolink:ChemicalSubstance capsazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_70773 chebi_ph7_3 CHEBI:70771 biolink:ChemicalSubstance 15-methylhexadecasphing-4-enine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_70771 chebi_ph7_3 OBA:0000011 biolink:OntologyClass actin filament length The length of a actin filament. go-plus.json length of actin filament http://purl.obolibrary.org/obo/OBA_0000011 CHEBI:137536 biolink:ChemicalSubstance (+)-corvol ether B go-plus.json http://purl.obolibrary.org/obo/CHEBI_137536 chebi_ph7_3 CHEBI:137535 biolink:ChemicalSubstance (+)-corvol ether A go-plus.json http://purl.obolibrary.org/obo/CHEBI_137535 chebi_ph7_3 CHEBI:137534 biolink:ChemicalSubstance 3-oxocholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137534 CHEBI:137533 biolink:ChemicalSubstance (-)-alpha-amorphene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137533 chebi_ph7_3 CHEBI:137539 biolink:ChemicalSubstance 3-oxocholan-24-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137539 CHEBI:137537 biolink:ChemicalSubstance 3-oxodeoxycholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137537 OBA:0000016 biolink:OntologyClass angiotensin levels in blood The amount of a angiotensin II when measured in blood. go-plus.json blood angiotensin II amount http://purl.obolibrary.org/obo/OBA_0000016 CHEBI:31178 biolink:ChemicalSubstance aklanonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31178 OBA:0000018 biolink:OntologyClass appetite The quality of a hunger motivation behavior. go-plus.json quality of hunger motivation behavior http://purl.obolibrary.org/obo/OBA_0000018 CHEBI:137532 biolink:ChemicalSubstance 3-oxochenodeoxycholoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137532 CHEBI:137531 biolink:ChemicalSubstance (3S)-(+)-asterisca-2(9),6-diene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137531 chebi_ph7_3 OBA:0000015 biolink:OntologyClass anatomical structure size The size of a anatomical structure. go-plus.json size of anatomical structure http://purl.obolibrary.org/obo/OBA_0000015 CHEBI:137530 biolink:ChemicalSubstance (2S,3R,6S,9S)-(-)-protoillud-7-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137530 chebi_ph7_3 CHEBI:137547 biolink:ChemicalSubstance (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137547 chebi_ph7_3 CHEBI:137546 biolink:ChemicalSubstance (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137546 chebi_ph7_3 CHEBI:137545 biolink:ChemicalSubstance pivaloyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_137545 CHEBI:31181 biolink:ChemicalSubstance aklavinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_31181 chebi_ph7_3 CHEBI:137544 biolink:ChemicalSubstance bis(hydroperoxy)icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137544 OBA:0000009 biolink:OntologyClass RNA stability The macromolecular stability of a RNA. go-plus.json macromolecular stability of RNA http://purl.obolibrary.org/obo/OBA_0000009 CHEBI:137548 biolink:ChemicalSubstance hydroperoxy(hydroxy)icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137548 OBA:0000006 biolink:OntologyClass Malpighian tubule diameter The diameter of a Malpighian tubule. go-plus.json diameter of Malpighian tubule http://purl.obolibrary.org/obo/OBA_0000006 OBA:0000007 biolink:OntologyClass Malpighian tubule size The size of a Malpighian tubule. go-plus.json size of Malpighian tubule http://purl.obolibrary.org/obo/OBA_0000007 CHEBI:137543 biolink:ChemicalSubstance (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137543 chebi_ph7_3 CHEBI:137542 biolink:ChemicalSubstance (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-icosatetraenoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_137542 chebi_ph7_3 OBA:0000001 biolink:OntologyClass biological attribute go-plus.json http://purl.obolibrary.org/obo/OBA_0000001 CHEBI:31186 biolink:ChemicalSubstance alfacalcidol go-plus.json http://purl.obolibrary.org/obo/CHEBI_31186 chebi_ph7_3 CHEBI:137541 biolink:ChemicalSubstance N-propanoyl-L-methionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_137541 CHEBI:137540 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-L-threonine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_137540 chebi_ph7_3 CHEBI:137514 biolink:ChemicalSubstance TRPA1 channel agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_137514 CHEBI:31157 biolink:ChemicalSubstance (+)-abscisic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_31157 chebi_ph7_3 CHEBI:45791 biolink:ChemicalSubstance triethylammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_45791 chebi_ph7_3 CHEBI:137525 biolink:ChemicalSubstance CDP-D-ribose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137525 chebi_ph7_3 CHEBI:137524 biolink:ChemicalSubstance CDP-D-ribulose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_137524 chebi_ph7_3 CHEBI:137523 biolink:ChemicalSubstance (-)-spiroviolene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137523 chebi_ph7_3 CHEBI:137522 biolink:ChemicalSubstance (+)-isoafricanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_137522 chebi_ph7_3 CHEBI:137529 biolink:ChemicalSubstance 20-hydroxyprostaglandin A1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137529 CHEBI:137528 biolink:ChemicalSubstance tsukubadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_137528 chebi_ph7_3 CHEBI:137526 biolink:ChemicalSubstance 20-hydroxyprostaglandin E1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_137526 OBA:0000052 biolink:OntologyClass cell shape The shape of a cell. go-plus.json shape of cell http://purl.obolibrary.org/obo/OBA_0000052 OBA:0000055 biolink:OntologyClass cell size The size of a cell. go-plus.json size of cell http://purl.obolibrary.org/obo/OBA_0000055 OBA:0000051 biolink:OntologyClass cell projection size The size of a cell projection. go-plus.json size of cell projection http://purl.obolibrary.org/obo/OBA_0000051 OBA:0000050 biolink:OntologyClass cell pH The pH of a cell. go-plus.json pH of cell http://purl.obolibrary.org/obo/OBA_0000050 UBERON:0006518 biolink:AnatomicalEntity right lung lobe A lobe of lung that is part of a right lung. go-plus.json lobe of right lung|lobe of the right lung http://purl.obolibrary.org/obo/UBERON_0006518 UBERON:0006526 biolink:AnatomicalEntity right lung alveolar system go-plus.json http://purl.obolibrary.org/obo/UBERON_0006526 UBERON:0006525 biolink:AnatomicalEntity left lung alveolar system go-plus.json http://purl.obolibrary.org/obo/UBERON_0006525 UBERON:0006524 biolink:AnatomicalEntity alveolar system System pertaining to a bronchus and alveoli. go-plus.json bronchoalveolar system|pulmonary alveolar system http://purl.obolibrary.org/obo/UBERON_0006524 OBA:0000057 biolink:OntologyClass cellular component size The size of a cellular_component. go-plus.json size of cellular_component http://purl.obolibrary.org/obo/OBA_0000057 OBA:0000056 biolink:OntologyClass cell volume The volume of a cell. go-plus.json volume of cell http://purl.obolibrary.org/obo/OBA_0000056 CHEBI:31132 biolink:ChemicalSubstance 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31132 OBA:0000058 biolink:OntologyClass cellular pH The acidity when measured in cell. go-plus.json http://purl.obolibrary.org/obo/OBA_0000058 BSPO:0000121 biolink:OntologyClass in_right_side_of X in_right_side_of Y <=> if Y is subdivided into left and right portions, X is part_of the right portion. BSPO:0000121 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000121 BSPO:0000120 biolink:OntologyClass in_left_side_of X in_left_side_of Y <=> if Y is subdivided into left and right portions, X is part_of the left portion. BSPO:0000120 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000120 BSPO:0000123 biolink:OntologyClass in_anterior_side_of X anterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the anterior portion. BSPO:0000123 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000123 BSPO:0000122 biolink:OntologyClass in_posterior_side_of X posterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the posterior portion. BSPO:0000122 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000122 BSPO:0000125 biolink:OntologyClass in_distal_side_of X distal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the distal portion. BSPO:0000125 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000125 BSPO:0000124 biolink:OntologyClass in_proximal_side_of X proximal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the proximal portion. BSPO:0000124 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000124 OBA:0000040 biolink:OntologyClass calcium ion concentration The concentration of of a calcium ion. go-plus.json concentration of of calcium ion http://purl.obolibrary.org/obo/OBA_0000040 BSPO:0000126 biolink:OntologyClass in_lateral_side_of X in_lateral_side_of Y <=> if X is in_left_side_of Y or X is in_right_side_of Y. X is often, but not always a paired structure BSPO:0000126 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000126 PATO:0000051 biolink:OntologyClass morphology A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. go-plus.json http://purl.obolibrary.org/obo/PATO_0000051 CHEBI:137502 biolink:ChemicalSubstance (S)-2,4-dihydroxy-3-oxobutanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_137502 PATO:0000052 biolink:OntologyClass shape A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). go-plus.json relational shape quality http://purl.obolibrary.org/obo/PATO_0000052 UBERON:0006514 biolink:AnatomicalEntity pallidum Part of what are called the basal ganglia of the brain which consist of the globus pallidus and the ventral pallidum. go-plus.json neuraxis pallidum|pallidum of neuraxis http://purl.obolibrary.org/obo/UBERON_0006514 OBA:0000046 biolink:OntologyClass cardiac muscle cell membrane potential The membrane potential of a cardiac muscle cell. go-plus.json membrane potential of cardiac muscle cell http://purl.obolibrary.org/obo/OBA_0000046 CHEBI:31144 biolink:ChemicalSubstance 8-demethyltetracenomycin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_31144 chebi_ph7_3 OBA:0000048 biolink:OntologyClass cell diameter The diameter of a cell. go-plus.json diameter of cell http://purl.obolibrary.org/obo/OBA_0000048 CHEBI:21794 biolink:ChemicalSubstance N-sulfoglucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21794 OBA:0000032 biolink:OntologyClass blood vessel size The size of a blood vessel. go-plus.json size of blood vessel http://purl.obolibrary.org/obo/OBA_0000032 CHEBI:31116 biolink:ChemicalSubstance 3-hexaprenyl-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31116 CHEBI:45764 biolink:ChemicalSubstance L-methionine (R)-S-oxide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_45764 chebi_ph7_3 NCBITaxon:91561 biolink:OrganismalEntity Artiodactyla go-plus.json even-toed ungulates|whales, hippos, ruminants, pigs, camels etc.|Cetartiodactyla http://purl.obolibrary.org/obo/NCBITaxon_91561 OBA:0000039 biolink:OntologyClass buoyancy go-plus.json http://purl.obolibrary.org/obo/OBA_0000039 CHEBI:31113 biolink:ChemicalSubstance 3-dimethylallyl-4-hydroxyphenylpyruvic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31113 CHEBI:31112 biolink:ChemicalSubstance 3-dimethylallyl-4-hydroxymandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31112 CHEBI:31111 biolink:ChemicalSubstance 3-dimethylallyl-4-hydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_31111 OBA:0000037 biolink:OntologyClass brood size go-plus.json http://purl.obolibrary.org/obo/OBA_0000037 OBA:0000036 biolink:OntologyClass body fluid levels The volume when measured in multicellular organism. go-plus.json http://purl.obolibrary.org/obo/OBA_0000036 OBA:0000022 biolink:OntologyClass autophagic vacuole size The size of a autophagosome. go-plus.json size of autophagosome http://purl.obolibrary.org/obo/OBA_0000022 BSPO:0000100 biolink:OntologyClass proximal_to x proximal_to y iff x is closer to the point of attachment with the body than y. BSPO:0000100 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000100 BSPO:0000102 biolink:OntologyClass ventral_to x ventral_to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly). BSPO:0000102 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000102 CHEBI:31128 biolink:ChemicalSubstance 4-hydroxyphenyl acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_31128 chebi_ph7_3 BSPO:0000107 biolink:OntologyClass deep_to BSPO:0000107 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000107 BSPO:0000108 biolink:OntologyClass superficial_to BSPO:0000108 go-plus.json http://purl.obolibrary.org/obo/BSPO_0000108 CHEBI:45757 biolink:ChemicalSubstance (5S)-5-(carboxymethyl)-L-proline go-plus.json http://purl.obolibrary.org/obo/CHEBI_45757 CHEBI:31121 biolink:ChemicalSubstance 4'''-demalonylsalvianin go-plus.json http://purl.obolibrary.org/obo/CHEBI_31121 OBA:0000023 biolink:OntologyClass axon diameter The diameter of a axon. go-plus.json diameter of axon http://purl.obolibrary.org/obo/OBA_0000023 UBERON:0002639 biolink:AnatomicalEntity midbrain reticular formation Part of the reticular formation located in the midbrain tegmentum go-plus.json tegmental reticular formation|formatio reticularis mesencephali|substantia reticularis mesencephali|formatio reticularis tegmenti mesencephali|formatio reticularis tegmentalis|reticular formation of midbrain|MBRF http://purl.obolibrary.org/obo/UBERON_0002639 CHEBI:84429 biolink:ChemicalSubstance 1-heptadecanoyl-2-stearoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84429 chebi_ph7_3 CHEBI:84428 biolink:ChemicalSubstance 1-heptadecanoyl-2-myristoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84428 chebi_ph7_3 CHEBI:84427 biolink:ChemicalSubstance 1-heptadecanoyl-2-lauroyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84427 chebi_ph7_3 CHEBI:84426 biolink:ChemicalSubstance FAHFA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84426 CHEBI:60461 biolink:ChemicalSubstance ditrans,polycis-dodecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60461 CHEBI:84425 biolink:ChemicalSubstance 9-PAHSA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84425 CHEBI:84424 biolink:ChemicalSubstance ubiquinol-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84424 chebi_ph7_3 CHEBI:60460 biolink:ChemicalSubstance ditrans,polycis-tridecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60460 CHEBI:60463 biolink:ChemicalSubstance 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60463 chebi_ph7_3 CHEBI:84423 biolink:ChemicalSubstance 3-demethylubiquinol-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84423 chebi_ph7_3 CHEBI:84422 biolink:ChemicalSubstance 3-demethylubiquinol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84422 chebi_ph7_3 CHEBI:60462 biolink:ChemicalSubstance ditrans,polycis-tetradecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60462 CHEBI:35498 biolink:ChemicalSubstance diuretic go-plus.json http://purl.obolibrary.org/obo/CHEBI_35498 PO:0006070 biolink:OntologyClass mesophyll The chloroplast-containing, photosynthetic parenchymatous tissue situated between the two epidermal layers of the leaf or leaf like organs. go-plus.json 葉肉 (Japanese, exact)|mesófilo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006070 CHEBI:60465 biolink:ChemicalSubstance alpha-L-galactose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60465 CHEBI:60464 biolink:ChemicalSubstance tri-trans,poly-cis-undecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60464 CHEBI:35497 biolink:ChemicalSubstance androgen antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_35497 CHEBI:60467 biolink:ChemicalSubstance D-alanyl-D-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60467 CHEBI:35499 biolink:ChemicalSubstance hallucinogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_35499 CHEBI:60466 biolink:ChemicalSubstance peptide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60466 chebi_ph7_3 CHEBI:60468 biolink:ChemicalSubstance ditrans,polycis-undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60468 CHEBI:35490 biolink:ChemicalSubstance trypanothione disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35490 UBERON:0002642 biolink:AnatomicalEntity cuneate fasciculus of medulla Part of cuneate fasciculus found in the medulla go-plus.json fasciculus cuneatus (myelencephali)|nucleus pulvinaris oromedialis (Hassler) http://purl.obolibrary.org/obo/UBERON_0002642 CHEBI:35492 biolink:ChemicalSubstance cystine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35492 chebi_ph7_3 CHEBI:35491 biolink:ChemicalSubstance L-cystine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35491 chebi_ph7_3 CHEBI:35494 biolink:ChemicalSubstance D-cystine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35494 CHEBI:35493 biolink:ChemicalSubstance antipyretic go-plus.json http://purl.obolibrary.org/obo/CHEBI_35493 CHEBI:35496 biolink:ChemicalSubstance fluorobenzenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_35496 PO:0006079 biolink:OntologyClass shoot system meristem A portion of meristem tissue (PO:0009013) that is part of a shoot system (PO:0009006). go-plus.json シュート分裂組織 (Japanese, exact)|meristema del epiblasto (epiblastema) (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006079 CHEBI:59466 biolink:ChemicalSubstance phosphatidylinositol mannoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_59466 CHEBI:60472 biolink:ChemicalSubstance 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60472 CHEBI:60471 biolink:ChemicalSubstance dUDP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60471 chebi_ph7_3 CHEBI:60473 biolink:ChemicalSubstance 5,10-methylenetetrahydrofolate polyglutamate macromolecule go-plus.json http://purl.obolibrary.org/obo/CHEBI_60473 chebi_ph7_3 CHEBI:84432 biolink:ChemicalSubstance ubiquinol-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84432 chebi_ph7_3 CHEBI:84431 biolink:ChemicalSubstance 3-demethylubiquinol-7 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84431 chebi_ph7_3 CHEBI:84430 biolink:ChemicalSubstance 1-heptadecanoyl-2-palmitoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84430 chebi_ph7_3 PO:0006063 biolink:OntologyClass plant ovary epidermis A portion of epidermis (PO:0005679) that is part of an plant ovary wall (PO:0005022). go-plus.json epidermis del ovario (Spanish, exact)|子房表皮 (Japanese, exact)|Poaceae ovary epidermis (narrow) http://purl.obolibrary.org/obo/PO_0006063 CHEBI:60479 biolink:ChemicalSubstance lysophosphatidylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60479 chebi_ph7_3 PO:0006060 biolink:OntologyClass filament epidermis A portion of stamen epidermis that is part of a filament. go-plus.json 花糸表皮 (Japanese, exact)|epidermis del filamento (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006060 UBERON:0002633 biolink:AnatomicalEntity motor nucleus of trigeminal nerve Nucleus located in the pontine tegmentum containing cells that give rise to motor innervation of the jaw through the trigeminal nerve. It receives both crossed and uncrossed fibers from the cerebral cortex (Heimer, L. The Human Brain and Spinal Cord, 2nd ed., 1996, pg 248). go-plus.json motor trigeminal nucleus|trigeminal V motor nucleus|motor nucleus of the trigeminal|motor nucleus of trigeminal nerve|nucleus motorius nervi trigemini|nucleus motorius nervi trigeminalis|trigeminal motor nuclei|nucleus motorius nervi trigemini|nV|motor nucleus of cranial nerve v|motor nucleus|motor nucleus of trigeminal|motor nucleus V|trigeminal motor nucleus|nucleus motorius trigeminalis|motor nucleus of the trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0002633 CHEBI:59458 biolink:ChemicalSubstance N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59458 chebi_ph7_3 CHEBI:59457 biolink:ChemicalSubstance 1-(5-phosphonato-beta-D-ribosyl)-5'-AMP(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59457 chebi_ph7_3 UBERON:0002618 biolink:AnatomicalEntity root of trochlear nerve go-plus.json trochlear nerve root|fibrae nervi trochlearis|central part of trochlear nerve|trochlear nerve/root|4nf|trochlear nerve tract|trochlear nerve fibers|trochlear nerve or its root http://purl.obolibrary.org/obo/UBERON_0002618 CHEBI:490095 biolink:ChemicalSubstance esculetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_490095 chebi_ph7_3 UBERON:0002613 biolink:AnatomicalEntity cerebellum globose nucleus The two or three small masses of gray matter that is located medial to the emboliform nucleus and lateral to the fastigial nucleus; it receives axons from the intermediate area of the cerebellar hemispheres and its afferents exit through the superior cerebellar peduncle. go-plus.json posterior interpositus nucleus|medial interpositus (globose) nucleus|nucleus globosus cerebelli|nucleus interpositus posterior|medial interpositus nucleus|posterior interposed nucleus|medial interposed nucleus|nucleus globosus|globose nucleus|nuclei globosi|nucleus interpositus posterior cerebelli http://purl.obolibrary.org/obo/UBERON_0002613 UBERON:0002616 biolink:AnatomicalEntity regional part of brain Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. go-plus.json anatomical structure of brain|neuroanatomical region|neuraxis segment|brain anatomical structure|brain biological structure|brain part|segment of brain|biological structure of brain http://purl.obolibrary.org/obo/UBERON_0002616 UBERON:0002615 biolink:AnatomicalEntity ventral tegmental decussation go-plus.json decussatio tegmenti ventralis|decussatio ventralis tegmenti|decussatio inferior (Forel)|inferior decussation (Forel's decussation)|ventral tegmental decussation (Forel)|decussation of forel|VTGX|decussatio tegmentalis anterior|ventral tegmental decussation of forel|anterior tegmental decussation http://purl.obolibrary.org/obo/UBERON_0002615 CHEBI:60481 biolink:ChemicalSubstance N',N'',N'''-triacetylfusarinine C go-plus.json http://purl.obolibrary.org/obo/CHEBI_60481 CHEBI:84447 biolink:ChemicalSubstance (5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84447 CHEBI:84446 biolink:ChemicalSubstance 3,4-dihydroxy-5-all-trans-heptaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84446 CHEBI:84445 biolink:ChemicalSubstance N-acylheptadecasphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84445 chebi_ph7_3 CHEBI:84443 biolink:ChemicalSubstance 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84443 chebi_ph7_3 CHEBI:60487 biolink:ChemicalSubstance adenosylcobinamide guanosyl diphosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60487 chebi_ph7_3 CHEBI:35476 biolink:ChemicalSubstance antipsychotic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35476 CHEBI:35475 biolink:ChemicalSubstance non-steroidal anti-inflammatory drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35475 CHEBI:84442 biolink:ChemicalSubstance 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84442 CHEBI:60486 biolink:ChemicalSubstance trehalose monomycolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60486 CHEBI:60489 biolink:ChemicalSubstance magnesium 13(1)-hydroxyprotoporphyrin 13-monomethyl ester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60489 chebi_ph7_3 CHEBI:60488 biolink:ChemicalSubstance cob(I)alamin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60488 chebi_ph7_3 CHEBI:35479 biolink:ChemicalSubstance alkali metal salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_35479 UBERON:0002623 biolink:AnatomicalEntity cerebral peduncle Synonym for macrodissected adult human tegmentum (Vicq d'Azyr, 1784; Swanson, 2000); pp. 555-556. Later used thus by for example His (1893b, p. 178), Herrick (1915, p. 160), Strong & Elwyn (1943, p. 17), Carpenter (1976, p. 367), Williams & Warwick (1980, p. 935). go-plus.json cerebral peduncle|CP|cerebal peduncle|pedunculi cerebri|pedunculus cerebri|pedunculus cerebri|cerebral peduncle (archaic)|peduncle of midbrain|tegmentum|pedunculus cerebralis http://purl.obolibrary.org/obo/UBERON_0002623 CHEBI:35470 biolink:ChemicalSubstance central nervous system drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35470 CHEBI:35472 biolink:ChemicalSubstance anti-inflammatory drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35472 CHEBI:35471 biolink:ChemicalSubstance psychotropic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35471 CHEBI:35474 biolink:ChemicalSubstance anxiolytic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35474 CHEBI:35473 biolink:ChemicalSubstance tranquilizing drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35473 PO:0006039 biolink:OntologyClass shoot-borne root epidermis A portion of root epidermis (PO:0006036) that is part of a shoot-borne root (PO:0000042). go-plus.json crown root epidermis (related)|不定根表皮 (Japanese, exact)|adventitious root epidermis (broad)|epidermis de la raíz adventicia (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006039 UBERON:0002602 biolink:AnatomicalEntity emboliform nucleus the small wedge shaped nucleus interposed between the dentate and fastigial nuclei; it receives axons from Purkinje cells of the intermediate area of the cerebral hemispheres and most of its efferent connections travel via the superior cerebellar peduncle go-plus.json cerebellar emboliform nucleus|anterior interpositus nucleus|nucleus emboliformis cerebelli|cerebellum emboliform nucleus|lateral interpositus nucleus|nucleus interpositus anterior cerebelli|embolus|lateral interpositus (emboliform) nucleus|anterior interposed nucleus|nucleus interpositus anterior|nucleus emboliformis http://purl.obolibrary.org/obo/UBERON_0002602 CHEBI:60490 biolink:ChemicalSubstance magnesium 13(1)-oxoprotoporphyrin 13-monomethyl ester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60490 chebi_ph7_3 CHEBI:60492 biolink:ChemicalSubstance magnesium protoporphyrin(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60492 chebi_ph7_3 CHEBI:60491 biolink:ChemicalSubstance magnesium protoporphyrin 13-monomethyl ester(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60491 chebi_ph7_3 CHEBI:60494 biolink:ChemicalSubstance 5-hydroxybenzimidazolylcob(I)amide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60494 chebi_ph7_3 CHEBI:60493 biolink:ChemicalSubstance adenosylcobalamin 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60493 chebi_ph7_3 CHEBI:84456 biolink:ChemicalSubstance 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84456 chebi_ph7_3 CHEBI:84455 biolink:ChemicalSubstance 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84455 CHEBI:35487 biolink:ChemicalSubstance EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35487 CHEBI:84454 biolink:ChemicalSubstance 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84454 chebi_ph7_3 CHEBI:35486 biolink:ChemicalSubstance maleate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_35486 CHEBI:84453 biolink:ChemicalSubstance 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84453 CHEBI:84452 biolink:ChemicalSubstance 3,4-dihydroxy-5-all-trans-octaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84452 chebi_ph7_3 CHEBI:35489 biolink:ChemicalSubstance organic disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35489 chebi_ph7_3 CHEBI:35488 biolink:ChemicalSubstance central nervous system depressant go-plus.json http://purl.obolibrary.org/obo/CHEBI_35488 CHEBI:84451 biolink:ChemicalSubstance 3,4-dihydroxy-5-all-trans-octaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84451 CHEBI:84450 biolink:ChemicalSubstance 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84450 chebi_ph7_3 PO:0006041 biolink:OntologyClass petal epidermis A portion of phyllome epidermis (PO:0025157) that is part of a petal (PO:0009032). go-plus.json 花弁表皮 (Japanese, exact)|epidermis del pétalo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006041 PO:0006040 biolink:OntologyClass sepal epidermis A portion of phyllome epidermis (PO:0025157) that is part of a sepal (PO:0009031). go-plus.json epidermis del sépalo (Spanish, exact)|がく片表皮 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006040 UBERON:0002610 biolink:AnatomicalEntity cochlear nuclear complex The cochlear nuclei consist of: (a) the dorsal cochlear nucleus, corresponding to the tuberculum acusticum on the dorso-lateral surface of the inferior peduncle; and (b) the ventral or accessory cochlear nucleus, placed between the two divisions of the nerve, on the ventral aspect of the inferior peduncle. [WP,unvetted]. go-plus.json nuclei cochleares|cochlear nuclei http://purl.obolibrary.org/obo/UBERON_0002610 PO:0006043 biolink:OntologyClass integument epidermis A portion of epidermis (PO:0005679) that is part of an integument (PO:0020021). go-plus.json epidermis del integumento (Spanish, exact)|Poaceae integument epidermis (narrow)|珠皮表皮 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006043 CHEBI:35481 biolink:ChemicalSubstance non-narcotic analgesic go-plus.json http://purl.obolibrary.org/obo/CHEBI_35481 CHEBI:35480 biolink:ChemicalSubstance analgesic go-plus.json http://purl.obolibrary.org/obo/CHEBI_35480 CHEBI:59436 biolink:ChemicalSubstance L-lactyl-2-diphospho-5'-guanosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_59436 PO:0006048 biolink:OntologyClass seed coat epidermis A portion of epidermis (PO:0005679) that is part of a seed coat (PO:0009088). go-plus.json 種子種皮表皮 (Japanese, exact)|epidermis de la cubierta de la semilla (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006048 CHEBI:59435 biolink:ChemicalSubstance L-lactyl-2-diphospho-5'-guanosine(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59435 chebi_ph7_3 CHEBI:35482 biolink:ChemicalSubstance opioid analgesic go-plus.json http://purl.obolibrary.org/obo/CHEBI_35482 CHEBI:35484 biolink:ChemicalSubstance phthalate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_35484 CHEBI:59433 biolink:ChemicalSubstance 2-phospho-L-lactate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59433 CHEBI:84468 biolink:ChemicalSubstance 12-PAHSA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84468 CHEBI:84467 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84467 chebi_ph7_3 CHEBI:84466 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84466 chebi_ph7_3 CHEBI:84465 biolink:ChemicalSubstance acyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84465 chebi_ph7_3 CHEBI:35453 biolink:ChemicalSubstance 5-dehydro-4-deoxy-D-glucarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35453 CHEBI:84462 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84462 chebi_ph7_3 CHEBI:84461 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84461 chebi_ph7_3 CHEBI:35457 biolink:ChemicalSubstance EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35457 GO:0061801 biolink:CellularComponent laminin-5B complex A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains. go-plus.json laminin 3B32 complex http://purl.obolibrary.org/obo/GO_0061801 GO:0061800 biolink:CellularComponent fibronectin fibril A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks. go-plus.json http://purl.obolibrary.org/obo/GO_0061800 GO:0061803 biolink:CellularComponent posterior cell cortex The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0061803 GO:0061802 biolink:CellularComponent anterior cell cortex The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis. go-plus.json http://purl.obolibrary.org/obo/GO_0061802 GO:0061805 biolink:BiologicalProcess mitotic spindle elongation (spindle phase three) The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B. go-plus.json mitotic spindle elongation during mitotic anaphase|mitotic anaphase spindle elongation|mitotic spindle elongation during anaphase http://purl.obolibrary.org/obo/GO_0061805 GO:0061804 biolink:BiologicalProcess mitotic spindle formation (spindle phase one) The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase. go-plus.json mitotic spindle elongation during mitotic prophase|mitotic spindle elongation during prophase|mitotic spindle elongation during prophase and prometaphase http://purl.obolibrary.org/obo/GO_0061804 GO:0061807 biolink:BiologicalProcess positive regulation of DNA recombination at centromere Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere. go-plus.json positive regulation of centromeric recombination http://purl.obolibrary.org/obo/GO_0061807 GO:0061806 biolink:BiologicalProcess regulation of DNA recombination at centromere Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA. go-plus.json regulation of centromeric recombination http://purl.obolibrary.org/obo/GO_0061806 UBERON:0002682 biolink:AnatomicalEntity abducens nucleus Nucleus located beneath the floor of the 4th ventricle in the pontine tegmentum, containing motor neurons innervating the lateral rectus muscle of the eye (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 533) go-plus.json abducens nerve nucleus|nucleus of abducens nerve (VI)|abducent nucleus|abducens VI nucleus|motor nucleus VI|sixth cranial nerve nucleus|abducens motor nuclei|nucleus nervi abducentis|nucleus abducens|abducens motor nucleus|nVI|abducens nucleus proper|nucleus nervi abducentis|nucleus of abducens nerve http://purl.obolibrary.org/obo/UBERON_0002682 GO:0061809 biolink:MolecularActivity NAD+ nucleotidase, cyclic ADP-ribose generating Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity. MetaCyc:NADNUCLEOSID-RXN|EC:3.2.2.6 go-plus.json http://purl.obolibrary.org/obo/GO_0061809 CHEBI:35452 biolink:ChemicalSubstance dTDP-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35452 GO:0061808 biolink:BiologicalProcess negative regulation of DNA recombination at centromere Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere. go-plus.json negative regulation of centromeric recombination http://purl.obolibrary.org/obo/GO_0061808 NCBITaxon:1783257 biolink:OrganismalEntity PVC group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1783257 NCBITaxon:85962 biolink:OrganismalEntity Helicobacter pylori 26695 go-plus.json Helicobacter pylori (strain 26695)|Helicobacter pylori ATCC 700392|Helicobacter pylori KE26695|Helicobacter pylori str. 26695|Helicobacter pylori strain 26695 http://purl.obolibrary.org/obo/NCBITaxon_85962 UBERON:0002668 biolink:AnatomicalEntity oculomotor nerve root Initial segment of the occulomotor nerve as it leaves the midbrain. go-plus.json oculomotor nerve fibers|oculomotor nerve tract|fibrae nervi oculomotorii|root of oculomotor nerve|central part of oculomotor nerve|3nf http://purl.obolibrary.org/obo/UBERON_0002668 CHEBI:59410 biolink:ChemicalSubstance 3-epi-6-deoxocathasterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_59410 chebi_ph7_3 CHEBI:35465 biolink:ChemicalSubstance (Z)-hexadec-7-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35465 CHEBI:35464 biolink:ChemicalSubstance (Z)-hexadec-11-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35464 CHEBI:84475 biolink:ChemicalSubstance 1-palmitoyl-sn-glycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84475 chebi_ph7_3 CHEBI:35467 biolink:ChemicalSubstance phosphorodiamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35467 CHEBI:84473 biolink:ChemicalSubstance 1-alkyl-2-methyl-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84473 chebi_ph7_3 CHEBI:35469 biolink:ChemicalSubstance antidepressant go-plus.json http://purl.obolibrary.org/obo/CHEBI_35469 CHEBI:84472 biolink:ChemicalSubstance 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84472 chebi_ph7_3 CHEBI:35468 biolink:ChemicalSubstance triazene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35468 chebi_ph7_3 CHEBI:84470 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84470 chebi_ph7_3 CHEBI:59418 biolink:ChemicalSubstance 15beta-hydroxyprogesterone go-plus.json http://purl.obolibrary.org/obo/CHEBI_59418 chebi_ph7_3 CHEBI:59414 biolink:ChemicalSubstance muramyl dipeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59414 CHEBI:59412 biolink:ChemicalSubstance amino tetrasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59412 UBERON:0002673 biolink:AnatomicalEntity vestibular nuclear complex Nuclear complex containing the vestibular nuclei. go-plus.json nuclei vestibulares|vestibular nuclei|vestibular nucleus|vestibular nuclei in medulla oblongata|nuclei vestibulares in medulla oblongata http://purl.obolibrary.org/obo/UBERON_0002673 CHEBI:59411 biolink:ChemicalSubstance (5alpha,22S,24R)-22-hydroxyergostan-3-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_59411 chebi_ph7_3 CHEBI:84489 biolink:ChemicalSubstance 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84489 chebi_ph7_3 CHEBI:35436 biolink:ChemicalSubstance D-glucoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_35436 chebi_ph7_3 GO:0061821 biolink:MolecularActivity telomeric D-loop binding Binding to a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus. go-plus.json telomeric Displacement-loop binding http://purl.obolibrary.org/obo/GO_0061821 CHEBI:84483 biolink:ChemicalSubstance 1-O-acyl-N-acetylsphingosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84483 chebi_ph7_3 GO:0061820 biolink:BiologicalProcess telomeric D-loop disassembly A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus. go-plus.json http://purl.obolibrary.org/obo/GO_0061820 GO:0061823 biolink:CellularComponent ring centriole A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum. go-plus.json http://purl.obolibrary.org/obo/GO_0061823 CHEBI:84481 biolink:ChemicalSubstance N,O-diacylethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84481 chebi_ph7_3 CHEBI:35438 biolink:ChemicalSubstance nickel coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_35438 GO:0061822 biolink:CellularComponent ciliary cap An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole. go-plus.json spermatid ciliary cap http://purl.obolibrary.org/obo/GO_0061822 GO:0061825 biolink:CellularComponent podosome core The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061825 GO:0061824 biolink:BiologicalProcess cytosolic ciliogenesis The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm. go-plus.json intracellular ciliogenesis http://purl.obolibrary.org/obo/GO_0061824 GO:0061827 biolink:CellularComponent sperm head The part of the late spermatid or spermatozoon that contains the nucleus and acrosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061827 GO:0061826 biolink:CellularComponent podosome ring The ring structure surrounding the podosome core, containing proteins such as vinculin and talin. go-plus.json http://purl.obolibrary.org/obo/GO_0061826 GO:0061829 biolink:CellularComponent basal tubulobulbar complex Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell. go-plus.json basal TBC http://purl.obolibrary.org/obo/GO_0061829 CHEBI:59403 biolink:ChemicalSubstance glutathione amide disulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59403 GO:0061828 biolink:CellularComponent apical tubulobulbar complex Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell. go-plus.json apical TBC http://purl.obolibrary.org/obo/GO_0061828 CHEBI:35443 biolink:ChemicalSubstance anthelminthic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35443 CHEBI:84497 biolink:ChemicalSubstance (omega-1)-hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84497 chebi_ph7_3 CHEBI:35442 biolink:ChemicalSubstance antiparasitic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35442 CHEBI:84496 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-heptaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84496 chebi_ph7_3 CHEBI:35444 biolink:ChemicalSubstance antinematodal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35444 GO:0061810 biolink:MolecularActivity NAD glycohydrolase activity Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate. EC:3.2.2.5|Reactome:R-HSA-9637699 go-plus.json http://purl.obolibrary.org/obo/GO_0061810 PO:0006085 biolink:OntologyClass root meristem A portion of meristem tissue (PO:0009013) that gives rise to a root (PO:0009005). go-plus.json meristema de la raíz (Spanish, exact)|meristematic zone (related)|根分裂組織 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006085 CHEBI:84494 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-heptaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84494 CHEBI:84493 biolink:ChemicalSubstance (omega-1)-ethyl fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84493 chebi_ph7_3 CHEBI:35446 biolink:ChemicalSubstance chlorobiphenyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_35446 GO:0061812 biolink:MolecularActivity cyclic ADP-ribose hydrolase Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR). go-plus.json http://purl.obolibrary.org/obo/GO_0061812 CHEBI:84492 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-hexaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84492 chebi_ph7_3 GO:0061811 biolink:MolecularActivity ADP-ribosyl cyclase activity Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide. go-plus.json http://purl.obolibrary.org/obo/GO_0061811 GO:0061814 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061814 PO:0006089 biolink:OntologyClass anther primordium A floral structure primordium (PO:0025477) that is committed to the development of an anther (PO:0009066). go-plus.json primordio de la antera (Spanish, exact)|portion of anther primordium tissue (exact)|葯原基(可視的） (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006089 CHEBI:84490 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84490 chebi_ph7_3 GO:0061813 biolink:MolecularActivity obsolete ARID domain binding OBSOLETE. Binding to a ARID domain. The AT-rich interaction domain (ARID) is an ~100-amino acid DNA-binding module found in a large number of eukaryotic transcription factors. go-plus.json http://purl.obolibrary.org/obo/GO_0061813 UBERON:0002653 biolink:AnatomicalEntity gracile fasciculus of medulla Part of gracile fasiculus located in the medulla go-plus.json medulla segment of fasciculus gracilis|fasciculus of goll|gracile fascicle (Goll)|Goll's tract|column of Goll|gracile fascicle of medulla|fasciculus gracilis (myelencephali)|fasciculus dorsolateralis gracilis (Golli)|gracile fascicle (Gall)|medulla segment of gracile fasciculus|gracile fasciculus of the medulla|tract of Gall http://purl.obolibrary.org/obo/UBERON_0002653 PO:0006088 biolink:OntologyClass primary sporogenous cell A native plant cell (PO:0025606) is formed by the division of the male archesporial initial. After several mitotic divisions these cells differentiate into pollen mother cells. go-plus.json célula esporógena primaria (Spanish, exact)|一次胞子形成細胞 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006088 GO:0061816 biolink:BiologicalProcess proteaphagy The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles. go-plus.json http://purl.obolibrary.org/obo/GO_0061816 GO:0061815 biolink:MolecularActivity deubiquitinase, acting on linear ubiquitin Catalysis of the hydrolysis of ubiquitin units from linear ubiquitin chains. go-plus.json Met1 linkage specific DUB|linear ubiquitin specific deubiquitinase activity|ubiquitinyl hydrolase activity, acting on linear ubiquitin http://purl.obolibrary.org/obo/GO_0061815 GO:0061818 biolink:BiologicalProcess tRNA folding The process of assisting in the folding of tRNAs into the correct tertiary structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061818 GO:0061817 biolink:BiologicalProcess endoplasmic reticulum-plasma membrane tethering The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers. go-plus.json ER-plasma membrane tethering http://purl.obolibrary.org/obo/GO_0061817 CHEBI:35441 biolink:ChemicalSubstance antiinfective agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35441 GO:0061819 biolink:BiologicalProcess telomeric DNA-containing double minutes formation A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase. go-plus.json TDMs formation http://purl.obolibrary.org/obo/GO_0061819 CHEBI:35440 biolink:ChemicalSubstance (1R,2S)-3-phenylcyclohexa-3,5-diene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35440 chebi_ph7_3 GO:0071198 biolink:CellularComponent Kv4.1-DPP6 channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1. CORUM:600 go-plus.json Kv4.1-DPPX channel complex http://purl.obolibrary.org/obo/GO_0071198 GO:0071197 biolink:CellularComponent Kv4.2-Kv4.3 channel complex A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3. CORUM:609 go-plus.json http://purl.obolibrary.org/obo/GO_0071197 GO:0071196 biolink:CellularComponent Kv4.3-KChIP1 channel complex A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3. CORUM:3091 go-plus.json http://purl.obolibrary.org/obo/GO_0071196 GO:0071195 biolink:CellularComponent Kv4.2-KChIP4 channel complex A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2. CORUM:3090 go-plus.json http://purl.obolibrary.org/obo/GO_0071195 GO:0071194 biolink:CellularComponent Kv4.2-KChIP3 channel complex A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2. CORUM:608 go-plus.json http://purl.obolibrary.org/obo/GO_0071194 GO:0071193 biolink:CellularComponent Kv4.2-KChIP2 channel complex A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2. CORUM:607 go-plus.json http://purl.obolibrary.org/obo/GO_0071193 GO:0071192 biolink:CellularComponent Kv4.2-KChIP1 channel complex A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2. CORUM:606 go-plus.json http://purl.obolibrary.org/obo/GO_0071192 GO:0071191 biolink:CellularComponent protocadherin-alpha-v7-protocadherin-gamma-b4 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdha7-Pcdhgb2 complex http://purl.obolibrary.org/obo/GO_0071191 GO:0071190 biolink:CellularComponent protocadherin-alpha-v7-protocadherin-gamma-b2 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdha7-Pcdhgb4 complex http://purl.obolibrary.org/obo/GO_0071190 PATO:0000411 biolink:OntologyClass circular A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center. go-plus.json round|rounded http://purl.obolibrary.org/obo/PATO_0000411 CHEBI:142567 biolink:ChemicalSubstance alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142567 chebi_ph7_3 CHEBI:142568 biolink:ChemicalSubstance beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142568 chebi_ph7_3 GO:0071199 biolink:CellularComponent Kv4.1-DPP10 channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1. CORUM:601 go-plus.json Kv4.1-DPPY channel complex http://purl.obolibrary.org/obo/GO_0071199 CHEBI:142554 biolink:ChemicalSubstance N(omega)-(ADP-D-ribosyl)-L-argininium(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_142554 chebi_ph7_3 CHEBI:60402 biolink:ChemicalSubstance Ins-1-P-Cer(d18:0/24:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60402 CHEBI:60405 biolink:ChemicalSubstance Ins-1-P-Cer(d18:0/26:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60405 CHEBI:60409 biolink:ChemicalSubstance Ins-1-P-Cer(d18:0/2-OH-26:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60409 CHEBI:142544 biolink:ChemicalSubstance tamsulosin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142544 chebi_ph7_3 CHEBI:142549 biolink:ChemicalSubstance ent-tamsulosin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142549 chebi_ph7_3 CHEBI:142548 biolink:ChemicalSubstance ent-tamsulosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_142548 CHEBI:60416 biolink:ChemicalSubstance Man-beta1-6-Ins-1-P-Cer(d18:0/24:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60416 CHEBI:142546 biolink:ChemicalSubstance 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_142546 NCBITaxon:1783272 biolink:OrganismalEntity Terrabacteria group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1783272 NCBITaxon:1783270 biolink:OrganismalEntity FCB group go-plus.json Fibrobacteres/Acidobacteria group|Fibrobacter/Acidobacteria group|Fibrobacteres-Chlorobi-Bacteroidetes superphylum http://purl.obolibrary.org/obo/NCBITaxon_1783270 NCBITaxon:1783275 biolink:OrganismalEntity TACK group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1783275 CHEBI:142533 biolink:ChemicalSubstance ->4)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142533 chebi_ph7_3 CHEBI:142532 biolink:ChemicalSubstance alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-beta-D-Glcp-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142532 CHEBI:60427 biolink:ChemicalSubstance dioleoyl phosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60427 UBERON:0002600 biolink:AnatomicalEntity limbic lobe Part of cerebral hemisphere located on the medial surface, forming a ring around the brain stem go-plus.json fornicate convolution|grande lobe limbique of Broca|fornicate gyrus|limbic lobe (carpenter)|fornicate lobe|gyrus fornicatus|lobus limbicus http://purl.obolibrary.org/obo/UBERON_0002600 PO:0006036 biolink:OntologyClass root epidermis A portion of epidermis (PO:0005679) that is part of a root (PO:0009005). go-plus.json epidermis de la raíz (Spanish, exact)|epiblem (related)|rhizodermis (related)|根表皮 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006036 PO:0006035 biolink:OntologyClass shoot system epidermis A portion of epidermis (PO:0005679) that is part of a shoot system (PO:0009006) and arises from the meristem L1 layer (PO:0009020). go-plus.json シュート表皮 (Japanese, exact)|epidermis del epiblasto (epiblastema) (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006035 CHEBI:142522 biolink:ChemicalSubstance beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-R group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142522 CHEBI:142521 biolink:ChemicalSubstance beta-D-GalpNAc-(1->4)-[alpha-Neup5Gc-(2->3)]-beta-D-Galp-(1->4)-R group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142521 CHEBI:60430 biolink:ChemicalSubstance 2-monolysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60430 CHEBI:60431 biolink:ChemicalSubstance 2,2'-dilysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60431 CHEBI:59497 biolink:ChemicalSubstance beta-D-galactofuranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_59497 chebi_ph7_3 CHEBI:142525 biolink:ChemicalSubstance 3-hydroxybutane-1,2,3-tricarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_142525 PO:0006023 biolink:OntologyClass bundle sheath A portion of ground tissue (PO:0025059) which comprises a layer or layers of cells surrounding the vascular bundles (PO:0005020) of leaves. It may consist of parenchyma (PO:0005421) or sclerenchyma (PO:0005427). go-plus.json 維管束鞘 (Japanese, exact)|vaina del haz (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006023 CHEBI:142510 biolink:ChemicalSubstance isonocardicin A zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142510 CHEBI:84404 biolink:ChemicalSubstance ceramide 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84404 chebi_ph7_3 CHEBI:84403 biolink:ChemicalSubstance phytoceramides go-plus.json http://purl.obolibrary.org/obo/CHEBI_84403 chebi_ph7_3 CHEBI:84400 biolink:ChemicalSubstance 1,1',2-trilinoleoyl-2'-palmitoyl cardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_84400 CHEBI:142518 biolink:ChemicalSubstance beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142518 chebi_ph7_3 CHEBI:142514 biolink:ChemicalSubstance ->8)-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142514 CHEBI:60449 biolink:ChemicalSubstance mannose-(1D-myo-inositol 1-phosphate)2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_60449 CHEBI:142513 biolink:ChemicalSubstance oxime anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142513 CHEBI:60448 biolink:ChemicalSubstance mannose-1D-myo-inositol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60448 PO:0006016 biolink:OntologyClass leaf epidermis A portion of phyllome epidermis (PO:0025157) that is part of a leaf (PO:0025034). go-plus.json phyllid epidermis (exact)|葉表皮 (Japanese, exact)|epidermis de la hoja (Spanish, exact)|foliage leaf epidermis (exact) http://purl.obolibrary.org/obo/PO_0006016 PO:0006015 biolink:OntologyClass female archesporial cell An archesporial cell (PO:0030056) that is part of a megasporangium (PO:0025201) and divides to give rise to a megasporocyte (PO:0000431). go-plus.json 雌胞原細胞 (Japanese, exact)|female archesporial initial (exact)|ovule archesporial cell (narrow)|célula femenina arquesporial (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006015 PO:0006014 biolink:OntologyClass male archesporial cell An archesporial cell (PO:0030056) that is part of a microsporangium (PO:0025202) and divides to gives rise to a microsporocyte (PO:0020047). go-plus.json male archesporial initial (exact)|雄性胞原細胞 (Japanese, exact)|anther archesporial cell (narrow)|célula masculina arquesporial (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006014 CHEBI:84417 biolink:ChemicalSubstance 1,2-di-palmitoleoyl-2-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84417 chebi_ph7_3 CHEBI:84414 biolink:ChemicalSubstance hexadecanoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_84414 CHEBI:84412 biolink:ChemicalSubstance tetradecanoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_84412 CHEBI:84411 biolink:ChemicalSubstance 3-dehydrosphingoid base(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84411 chebi_ph7_3 CHEBI:84410 biolink:ChemicalSubstance sphingoid base(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84410 chebi_ph7_3 CHEBI:60454 biolink:ChemicalSubstance Fe-coproporphyrin III go-plus.json http://purl.obolibrary.org/obo/CHEBI_60454 CHEBI:142508 biolink:ChemicalSubstance beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142508 chebi_ph7_3 CHEBI:59475 biolink:ChemicalSubstance 6-O-acyl-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_59475 CHEBI:60459 biolink:ChemicalSubstance trans,poly-cis-decaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60459 PO:0006001 biolink:OntologyClass phyllome A lateral plant organ (PO:0009008) produced by a shoot apical meristem (PO:0020148). go-plus.json filoma (Spanish, exact)|フィロム、葉(的）器官 (Japanese, exact) http://purl.obolibrary.org/obo/PO_0006001 PO:0006005 biolink:OntologyClass carpel anlagen A phyllome anlagen (PO:0025430) that will give rise to a carpel primordium (PO:0004703) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). go-plus.json 心皮原基 (Japanese, exact)|esbozo de carpelo (Spanish, exact) http://purl.obolibrary.org/obo/PO_0006005 GO:0046165 biolink:BiologicalProcess alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. go-plus.json alcohol anabolism|alcohol synthesis|alcohol formation|alcohol biosynthesis http://purl.obolibrary.org/obo/GO_0046165 GO:0071121 biolink:CellularComponent alpha9-beta1 integrin-VEGF-D complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D. go-plus.json ITGA9-ITGB1-FIGF complex http://purl.obolibrary.org/obo/GO_0071121 GO:0071120 biolink:CellularComponent alpha4-beta1 integrin-CD47 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47. go-plus.json ITGA4-ITGB1-CB47 complex http://purl.obolibrary.org/obo/GO_0071120 GO:0046164 biolink:BiologicalProcess alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. go-plus.json alcohol degradation|alcohol breakdown|alcohol catabolism http://purl.obolibrary.org/obo/GO_0046164 GO:0046163 biolink:BiologicalProcess heme C catabolic process The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f. go-plus.json heme C breakdown|heme C catabolism|haem C catabolism|haem C catabolic process|heme C degradation http://purl.obolibrary.org/obo/GO_0046163 GO:0046162 biolink:BiologicalProcess heme C metabolic process The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f. go-plus.json heme C metabolism|haem C metabolic process|haem C metabolism http://purl.obolibrary.org/obo/GO_0046162 GO:0046161 biolink:BiologicalProcess heme a catabolic process The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3. go-plus.json heme a catabolism|heme a breakdown|haem a catabolism|haem a catabolic process|heme a degradation http://purl.obolibrary.org/obo/GO_0046161 GO:1900239 biolink:BiologicalProcess regulation of phenotypic switching Any process that modulates the frequency, rate or extent of phenotypic switching. go-plus.json regulation of phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1900239 GO:1900238 biolink:BiologicalProcess regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway. go-plus.json regulation of metanephric mesenchyme chemotaxis by platelet-derived growth factor receptor-beta signaling pathway|regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway http://purl.obolibrary.org/obo/GO_1900238 GO:0046160 biolink:BiologicalProcess heme a metabolic process The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3. go-plus.json heme a metabolism|haem a metabolism|haem a metabolic process http://purl.obolibrary.org/obo/GO_0046160 GO:1900235 biolink:BiologicalProcess negative regulation of Kit signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway. go-plus.json negative regulation of Kit signalling pathway|down-regulation of Kit signaling pathway|down regulation of stem cell factor receptor signaling pathway|down-regulation of stem cell factor signaling pathway|negative regulation of stem cell factor signaling pathway|inhibition of Kit signaling pathway|downregulation of stem cell factor receptor signaling pathway|downregulation of stem cell factor signaling pathway|negative regulation of stem cell factor receptor signaling pathway|down-regulation of stem cell factor receptor signaling pathway|down regulation of stem cell factor signaling pathway|down regulation of Kit signaling pathway|downregulation of Kit signaling pathway|inhibition of stem cell factor signaling pathway|inhibition of stem cell factor receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900235 GO:1900234 biolink:BiologicalProcess regulation of Kit signaling pathway Any process that modulates the frequency, rate or extent of Kit signaling pathway. go-plus.json regulation of stem cell factor receptor signaling pathway|regulation of Kit signalling pathway|regulation of stem cell factor signaling pathway http://purl.obolibrary.org/obo/GO_1900234 GO:1900237 biolink:BiologicalProcess positive regulation of induction of conjugation with cellular fusion Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion. go-plus.json up regulation of induction of conjugation with cellular fusion|up-regulation of induction of conjugation with cellular fusion|upregulation of induction of conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_1900237 GO:1900236 biolink:BiologicalProcess positive regulation of Kit signaling pathway Any process that activates or increases the frequency, rate or extent of Kit signaling pathway. go-plus.json upregulation of stem cell factor receptor signaling pathway|activation of stem cell factor signaling pathway|positive regulation of Kit signalling pathway|up-regulation of Kit signaling pathway|positive regulation of stem cell factor signaling pathway|up regulation of stem cell factor receptor signaling pathway|up regulation of stem cell factor signaling pathway|positive regulation of stem cell factor receptor signaling pathway|upregulation of Kit signaling pathway|activation of stem cell factor receptor signaling pathway|upregulation of stem cell factor signaling pathway|up-regulation of stem cell factor receptor signaling pathway|up regulation of Kit signaling pathway|activation of Kit signaling pathway|up-regulation of stem cell factor signaling pathway http://purl.obolibrary.org/obo/GO_1900236 GO:0046169 biolink:BiologicalProcess methanol biosynthetic process The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent. go-plus.json methanol biosynthesis|methanol anabolism|methanol synthesis|methanol formation http://purl.obolibrary.org/obo/GO_0046169 GO:1900231 biolink:BiologicalProcess regulation of single-species biofilm formation on inanimate substrate Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate. go-plus.json http://purl.obolibrary.org/obo/GO_1900231 GO:0046168 biolink:BiologicalProcess glycerol-3-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol. go-plus.json glycerol-3-phosphate degradation|glycerol-3-phosphate breakdown|glycerol-3-phosphate catabolism http://purl.obolibrary.org/obo/GO_0046168 GO:1900230 biolink:BiologicalProcess positive regulation of single-species biofilm formation in or on host organism Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism. go-plus.json up-regulation of single-species biofilm formation in or on host organism|upregulation of single-species biofilm formation in or on host organism|up regulation of single-species biofilm formation in or on host organism|activation of single-species biofilm formation in or on host organism http://purl.obolibrary.org/obo/GO_1900230 GO:0046167 biolink:BiologicalProcess glycerol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol. go-plus.json glycerol-3-phosphate biosynthesis|glycerol-3-phosphate anabolism|glycerol-3-phosphate synthesis|glycerol-3-phosphate formation http://purl.obolibrary.org/obo/GO_0046167 GO:1900233 biolink:BiologicalProcess positive regulation of single-species biofilm formation on inanimate substrate Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate. go-plus.json upregulation of single-species biofilm formation on inanimate substrate|up regulation of single-species biofilm formation on inanimate substrate|activation of single-species biofilm formation on inanimate substrate|up-regulation of single-species biofilm formation on inanimate substrate http://purl.obolibrary.org/obo/GO_1900233 GO:0046166 biolink:BiologicalProcess glyceraldehyde-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis. go-plus.json glyceraldehyde-3-phosphate biosynthesis|glyceraldehyde 3-phosphate biosynthetic process|glyceraldehyde 3-phosphate biosynthesis|glyceraldehyde-3-phosphate anabolism|glyceraldehyde-3-phosphate synthesis|glyceraldehyde-3-phosphate formation http://purl.obolibrary.org/obo/GO_0046166 GO:1900232 biolink:BiologicalProcess negative regulation of single-species biofilm formation on inanimate substrate Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate. go-plus.json down regulation of single-species biofilm formation on inanimate substrate|downregulation of single-species biofilm formation on inanimate substrate|down-regulation of single-species biofilm formation on inanimate substrate|inhibition of single-species biofilm formation on inanimate substrate http://purl.obolibrary.org/obo/GO_1900232 GO:1900240 biolink:BiologicalProcess negative regulation of phenotypic switching Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching. go-plus.json negative regulation of phenotypic dimorphism|down-regulation of phenotypic dimorphism|down-regulation of phenotypic switching|downregulation of phenotypic switching|inhibition of phenotypic dimorphism|down regulation of phenotypic switching|inhibition of phenotypic switching|down regulation of phenotypic dimorphism|downregulation of phenotypic dimorphism http://purl.obolibrary.org/obo/GO_1900240 GO:0071129 biolink:CellularComponent alphaV-beta3 integrin-LPP3 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3. go-plus.json ITGAV-ITGB3-PPAP2B complex http://purl.obolibrary.org/obo/GO_0071129 GO:0071128 biolink:CellularComponent alpha5-beta1 integrin-osteopontin complex A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin. go-plus.json ITGA5-ITGB1-SPP1 complex http://purl.obolibrary.org/obo/GO_0071128 GO:0071127 biolink:CellularComponent alpha9-beta1 integrin-osteopontin complex A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin. go-plus.json ITGA9-ITGB1-SPP1 complex http://purl.obolibrary.org/obo/GO_0071127 GO:0071126 biolink:CellularComponent alphaV-beta6 integrin-osteopontin complex A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin. go-plus.json ITGAV-ITGB6-SPP1 complex http://purl.obolibrary.org/obo/GO_0071126 GO:0071125 biolink:CellularComponent alphaV-beta3 integrin-EGFR complex A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor. go-plus.json ITGAV-ITGB3-EGFR complex http://purl.obolibrary.org/obo/GO_0071125 GO:0071124 biolink:CellularComponent alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2. go-plus.json ITGA1-ITGB1-PTPN2 complex http://purl.obolibrary.org/obo/GO_0071124 GO:0071123 biolink:CellularComponent alpha9-beta1 integrin-VEGF-C complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C. go-plus.json ITGA9-ITGB1-VEGFC complex http://purl.obolibrary.org/obo/GO_0071123 GO:0071122 biolink:CellularComponent alpha9-beta1 integrin-VEGF-A complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A. go-plus.json ITGA9-ITGB1-VEGFA complex http://purl.obolibrary.org/obo/GO_0071122 GO:0046176 biolink:BiologicalProcess aldonic acid catabolic process The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group. go-plus.json aldonic acid catabolism|aldonic acid degradation|aldonic acid breakdown http://purl.obolibrary.org/obo/GO_0046176 GO:0071110 biolink:BiologicalProcess histone biotinylation The modification of a histone by the addition of a biotinyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0071110 GO:0046175 biolink:BiologicalProcess aldonic acid biosynthetic process The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group. go-plus.json aldonic acid anabolism|aldonic acid biosynthesis|aldonic acid synthesis|aldonic acid formation http://purl.obolibrary.org/obo/GO_0046175 GO:0046174 biolink:BiologicalProcess polyol catabolic process The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. go-plus.json polyol catabolism|polyhydric alcohol catabolic process|polyol degradation|polyol breakdown http://purl.obolibrary.org/obo/GO_0046174 GO:0046173 biolink:BiologicalProcess polyol biosynthetic process The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. go-plus.json polyol biosynthesis|polyol anabolism|polyol synthesis|polyol formation|polyhydric alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0046173 GO:0046172 biolink:BiologicalProcess octanol catabolic process The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH. go-plus.json octanol catabolism|octanol degradation|octanol breakdown http://purl.obolibrary.org/obo/GO_0046172 GO:1900249 biolink:BiologicalProcess positive regulation of cytoplasmic translational elongation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation. go-plus.json up regulation of cytoplasmic translational elongation|upregulation of cytoplasmic translational elongation|up-regulation of cytoplasmic translational elongation|activation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_1900249 GO:0046171 biolink:BiologicalProcess octanol biosynthetic process The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH. go-plus.json octanol biosynthesis|octanol anabolism|octanol synthesis|octanol formation http://purl.obolibrary.org/obo/GO_0046171 GO:0046170 biolink:BiologicalProcess methanol catabolic process The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent. go-plus.json methanol degradation|methanol catabolism|methanol breakdown http://purl.obolibrary.org/obo/GO_0046170 GO:1900246 biolink:BiologicalProcess positive regulation of RIG-I signaling pathway Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway. go-plus.json up-regulation of RIG-I signaling pathway|up regulation of DDX58 signaling pathway|positive regulation of DDX58 signaling pathway|activation of DDX58 signaling pathway|positive regulation of retinoic acid inducible gene I signaling pathway|upregulation of RIG-I signaling pathway|positive regulation of RIG-I signalling pathway|up regulation of retinoic acid inducible gene I signaling pathway|up-regulation of DDX58 signaling pathway|up regulation of RIG-I signaling pathway|upregulation of retinoic acid inducible gene I signaling pathway|activation of RIG-I signaling pathway|upregulation of DDX58 signaling pathway|up-regulation of retinoic acid inducible gene I signaling pathway|activation of retinoic acid inducible gene I signaling pathway http://purl.obolibrary.org/obo/GO_1900246 GO:1900245 biolink:BiologicalProcess positive regulation of MDA-5 signaling pathway Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway. go-plus.json upregulation of IFIH1 signaling pathway|upregulation of MDA-5 signaling pathway|up-regulation of melanoma differentiation-associated gene 5 signaling pathway|activation of melanoma differentiation-associated gene 5 signaling pathway|upregulation of MDA5 signaling pathway|up regulation of IFIH1 signaling pathway|activation of IFIH1 signaling pathway|positive regulation of IFIH1 signaling pathway|up regulation of MDA-5 signaling pathway|activation of MDA-5 signaling pathway|positive regulation of MDA-5 signalling pathway|positive regulation of melanoma differentiation-associated gene 5 signaling pathway|up-regulation of MDA5 signaling pathway|up regulation of melanoma differentiation-associated gene 5 signaling pathway|up-regulation of IFIH1 signaling pathway|activation of MDA5 signaling pathway|up-regulation of MDA-5 signaling pathway|upregulation of melanoma differentiation-associated gene 5 signaling pathway|positive regulation of MDA5 signaling pathway|up regulation of MDA5 signaling pathway http://purl.obolibrary.org/obo/GO_1900245 GO:1900248 biolink:BiologicalProcess negative regulation of cytoplasmic translational elongation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation. go-plus.json downregulation of cytoplasmic translational elongation|down regulation of cytoplasmic translational elongation|inhibition of cytoplasmic translational elongation|down-regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_1900248 GO:1900247 biolink:BiologicalProcess regulation of cytoplasmic translational elongation Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. go-plus.json http://purl.obolibrary.org/obo/GO_1900247 GO:1900242 biolink:BiologicalProcess regulation of synaptic vesicle endocytosis Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis. go-plus.json regulation of synaptic vesicle retrieval http://purl.obolibrary.org/obo/GO_1900242 goslim_synapse GO:0061791 biolink:MolecularActivity GTPase motor activity A motor activity driven by GTP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0061791 GO:0061790 biolink:BiologicalProcess dense core granule docking The initial attachment of a dense core granule membrane to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0061790 GO:0046179 biolink:BiologicalProcess keto-D-gluconate biosynthetic process The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose. go-plus.json keto-D-gluconate anabolism|keto-D-gluconate synthesis|keto-D-gluconate formation|keto-D-gluconate biosynthesis http://purl.obolibrary.org/obo/GO_0046179 GO:1900241 biolink:BiologicalProcess positive regulation of phenotypic switching Any process that activates or increases the frequency, rate or extent of phenotypic switching. go-plus.json activation of phenotypic dimorphism|up-regulation of phenotypic dimorphism|up regulation of phenotypic switching|upregulation of phenotypic dimorphism|upregulation of phenotypic switching|up regulation of phenotypic dimorphism|positive regulation of phenotypic dimorphism|activation of phenotypic switching|up-regulation of phenotypic switching http://purl.obolibrary.org/obo/GO_1900241 GO:1900244 biolink:BiologicalProcess positive regulation of synaptic vesicle endocytosis Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis. go-plus.json activation of synaptic vesicle endocytosis|up-regulation of synaptic vesicle retrieval|up regulation of synaptic vesicle endocytosis|activation of synaptic vesicle retrieval|positive regulation of synaptic vesicle retrieval|up regulation of synaptic vesicle retrieval|upregulation of synaptic vesicle endocytosis|up-regulation of synaptic vesicle endocytosis|upregulation of synaptic vesicle retrieval http://purl.obolibrary.org/obo/GO_1900244 GO:0061793 biolink:CellularComponent chromatin lock complex A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping. go-plus.json nucleosome bridging complex http://purl.obolibrary.org/obo/GO_0061793 GO:0046178 biolink:BiologicalProcess D-gluconate biosynthetic process The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose. go-plus.json D-gluconate synthesis|D-gluconate formation|D-gluconate biosynthesis|D-gluconate anabolism http://purl.obolibrary.org/obo/GO_0046178 GO:1900243 biolink:BiologicalProcess negative regulation of synaptic vesicle endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis. go-plus.json inhibition of synaptic vesicle retrieval|down-regulation of synaptic vesicle endocytosis|negative regulation of synaptic vesicle retrieval|down-regulation of synaptic vesicle retrieval|downregulation of synaptic vesicle endocytosis|down regulation of synaptic vesicle endocytosis|inhibition of synaptic vesicle endocytosis|downregulation of synaptic vesicle retrieval|down regulation of synaptic vesicle retrieval http://purl.obolibrary.org/obo/GO_1900243 GO:0046177 biolink:BiologicalProcess D-gluconate catabolic process The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose. MetaCyc:GLUCONSUPER-PWY go-plus.json D-gluconate degradation|D-gluconate breakdown|D-gluconate catabolism http://purl.obolibrary.org/obo/GO_0046177 GO:0061792 biolink:BiologicalProcess secretory granule maturation Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling. go-plus.json http://purl.obolibrary.org/obo/GO_0061792 GO:0061795 biolink:BiologicalProcess Golgi lumen acidification Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion. go-plus.json http://purl.obolibrary.org/obo/GO_0061795 GO:0061794 biolink:BiologicalProcess conidium development The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. go-plus.json http://purl.obolibrary.org/obo/GO_0061794 GO:0061797 biolink:MolecularActivity pH-gated chloride channel activity A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH. go-plus.json http://purl.obolibrary.org/obo/GO_0061797 GO:0061796 biolink:BiologicalProcess membrane addition at site of mitotic cytokinesis A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion. go-plus.json http://purl.obolibrary.org/obo/GO_0061796 GO:0061799 biolink:MolecularActivity cyclic pyranopterin monophosphate synthase activity Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate. MetaCyc:RXN-17809|RHEA:49580|EC:4.6.1.17 go-plus.json http://purl.obolibrary.org/obo/GO_0061799 GO:0061798 biolink:MolecularActivity GTP 3',8'-cyclase activity Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate. EC:4.1.99.22|MetaCyc:RXN-8340|RHEA:49576 go-plus.json http://purl.obolibrary.org/obo/GO_0061798 GO:0071119 biolink:CellularComponent alpha7-beta1 integrin-nicotinamide riboside kinase complex A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP). go-plus.json ITGA7-ITGB1-ITGB1BP3 complex http://purl.obolibrary.org/obo/GO_0071119 GO:0071118 biolink:CellularComponent alphaV-beta3 integrin-NOV complex A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV. go-plus.json ITGAV-ITGB3-FN-1-NOV complex http://purl.obolibrary.org/obo/GO_0071118 GO:0071117 biolink:CellularComponent alpha5-beta1 integrin-fibronectin-NOV complex A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV. go-plus.json ITGA5-ITGB1-FN-1-NOV complex http://purl.obolibrary.org/obo/GO_0071117 GO:0071116 biolink:CellularComponent alpha6-beta1 integrin-CYR61 complex A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis. go-plus.json ITGA6-ITGB1-CYR61 complex http://purl.obolibrary.org/obo/GO_0071116 GO:0071115 biolink:CellularComponent alpha5-beta1 integrin-endostatin complex A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen. go-plus.json ITGA5-ITGB1-CAL4A3 complex http://purl.obolibrary.org/obo/GO_0071115 GO:0071114 biolink:CellularComponent alphaV-beta3 integrin-tumstatin complex A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen. go-plus.json ITGAV-ITGB3-COL4A3 complex http://purl.obolibrary.org/obo/GO_0071114 GO:0071113 biolink:CellularComponent alphaIIb-beta3 integrin-ICAM-4 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4. go-plus.json ITGAIIb-ITGB3-ICAM4 complex http://purl.obolibrary.org/obo/GO_0071113 GO:0071112 biolink:CellularComponent alpha4-beta4 integrin-EMILIN-1 complex A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN). go-plus.json ITGA4-ITGB4-EMILIN1 complex http://purl.obolibrary.org/obo/GO_0071112 GO:0071111 biolink:MolecularActivity cyclic-guanylate-specific phosphodiesterase activity Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+). RHEA:24902|EC:3.1.4.52|MetaCyc:RXN0-4181|KEGG_REACTION:R08991 go-plus.json VieA|cyclic bis(3->5')diguanylate phosphodiesterase activity|c-di-GMP phosphodiesterase activity|PDEA1|phosphodiesterase A1 activity|c-di-GMP-specific phosphodiesterase activity http://purl.obolibrary.org/obo/GO_0071111 GO:0046187 biolink:BiologicalProcess acetaldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. go-plus.json acetaldehyde degradation|acetaldehyde breakdown|acetaldehyde catabolism http://purl.obolibrary.org/obo/GO_0046187 GO:0071143 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071143 GO:0071142 biolink:CellularComponent homomeric SMAD protein complex A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive. go-plus.json SMAD1 homotrimer complex|SMAD2 homotrimer complex|SMAD3 protein complex|SMAD3 homotrimer complex|SMAD2 protein complex|SMAD1 protein complex http://purl.obolibrary.org/obo/GO_0071142 GO:0046186 biolink:BiologicalProcess acetaldehyde biosynthetic process The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. go-plus.json acetaldehyde anabolism|acetaldehyde synthesis|acetaldehyde formation|acetaldehyde biosynthesis http://purl.obolibrary.org/obo/GO_0046186 GO:0046185 biolink:BiologicalProcess aldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. go-plus.json aldehyde catabolism|aldehyde degradation|aldehyde breakdown http://purl.obolibrary.org/obo/GO_0046185 GO:0071141 biolink:CellularComponent SMAD protein complex A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven. go-plus.json SMAD complex http://purl.obolibrary.org/obo/GO_0071141 GO:0046184 biolink:BiologicalProcess aldehyde biosynthetic process The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O. go-plus.json aldehyde anabolism|aldehyde synthesis|aldehyde formation|aldehyde biosynthesis http://purl.obolibrary.org/obo/GO_0046184 OBO:GOCHE_63046 biolink:OntologyClass substance with emulsifier role go-plus.json http://purl.obolibrary.org/obo/GOCHE_63046 3_STAR GO:0071140 biolink:BiologicalProcess resolution of mitotic recombination intermediates The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged. go-plus.json http://purl.obolibrary.org/obo/GO_0071140 GO:0046183 biolink:BiologicalProcess L-idonate catabolic process The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. go-plus.json L-idonate degradation|L-idonate breakdown|L-idonate catabolism http://purl.obolibrary.org/obo/GO_0046183 GO:0046182 biolink:BiologicalProcess L-idonate biosynthetic process The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. go-plus.json L-idonate biosynthesis|L-idonate anabolism|L-idonate synthesis|L-idonate formation http://purl.obolibrary.org/obo/GO_0046182 GO:0046181 biolink:BiologicalProcess ketogluconate catabolic process The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group. go-plus.json ketogluconate degradation|ketogluconate breakdown|ketogluconate catabolism http://purl.obolibrary.org/obo/GO_0046181 GO:0046180 biolink:BiologicalProcess ketogluconate biosynthetic process The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group. go-plus.json ketogluconate anabolism|ketogluconate biosynthesis|ketogluconate synthesis|ketogluconate formation http://purl.obolibrary.org/obo/GO_0046180 GO:1900257 biolink:BiologicalProcess negative regulation of beta1-adrenergic receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of beta1-adrenergic receptor activity. go-plus.json down-regulation of beta1-adrenergic receptor activity|downregulation of beta1 adrenoceptor|down regulation of beta1 adrenoceptor|downregulation of beta1-adrenergic receptor activity|down regulation of beta1-adrenergic receptor activity|inhibition of beta1-adrenergic receptor activity|inhibition of beta1 adrenoceptor|negative regulation of beta1 adrenoceptor|down-regulation of beta1 adrenoceptor http://purl.obolibrary.org/obo/GO_1900257 GO:1900256 biolink:BiologicalProcess regulation of beta1-adrenergic receptor activity Any process that modulates the frequency, rate or extent of beta1-adrenergic receptor activity. go-plus.json regulation of beta1 adrenoceptor http://purl.obolibrary.org/obo/GO_1900256 GO:1900259 biolink:BiologicalProcess regulation of RNA-directed 5'-3' RNA polymerase activity Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity. go-plus.json regulation of ribonucleic synthetase activity|regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|regulation of RNA-directed RNA polymerase activity|regulation of RNA synthetase activity|regulation of RNA-dependent RNA polymerase activity|regulation of RNA replicase activity|regulation of 3D polymerase activity|regulation of ribonucleic replicase activity|regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|regulation of RNA nucleotidyltransferase (RNA-directed) activity|regulation of phage f2 replicase|regulation of Q-beta replicase activity|regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|regulation of ribonucleic acid replicase activity|regulation of PB1 proteins|regulation of polymerase L|regulation of transcriptase|regulation of RDRP|regulation of PB2 proteins|regulation of RNA-dependent RNA replicase activity http://purl.obolibrary.org/obo/GO_1900259 GO:1900258 biolink:BiologicalProcess positive regulation of beta1-adrenergic receptor activity Any process that activates or increases the frequency, rate or extent of beta1-adrenergic receptor activity. go-plus.json positive regulation of beta1 adrenoceptor|up regulation of beta1 adrenoceptor|up regulation of beta1-adrenergic receptor activity|upregulation of beta1 adrenoceptor|upregulation of beta1-adrenergic receptor activity|up-regulation of beta1 adrenoceptor|up-regulation of beta1-adrenergic receptor activity|activation of beta1-adrenergic receptor activity|activation of beta1 adrenoceptor http://purl.obolibrary.org/obo/GO_1900258 GO:0046189 biolink:BiologicalProcess phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. go-plus.json phenol-containing compound anabolism|phenol-containing compound synthesis|phenol-containing compound formation|phenol-containing compound biosynthesis http://purl.obolibrary.org/obo/GO_0046189 GO:0046188 biolink:BiologicalProcess methane catabolic process The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. go-plus.json methane degradation|methane breakdown|methane catabolism http://purl.obolibrary.org/obo/GO_0046188 GO:1900260 biolink:BiologicalProcess negative regulation of RNA-directed 5'-3' RNA polymerase activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity. go-plus.json inhibition of ribonucleic replicase activity|downregulation of Q-beta replicase activity|inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity|inhibition of ribonucleic synthetase activity|downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|inhibition of RNA nucleotidyltransferase (RNA-directed) activity|down regulation of ribonucleic acid replicase activity|inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA-directed RNA polymerase activity|downregulation of PB1 proteins|downregulation of polymerase L|inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|downregulation of RDRP|downregulation of PB2 proteins|down regulation of transcriptase|negative regulation of RNA replicase activity|down-regulation of RNA replicase activity|downregulation of RNA-dependent RNA replicase activity|downregulation of ribonucleic acid replicase activity|inhibition of phage f2 replicase|down regulation of polymerase L|down-regulation of RNA-directed RNA polymerase activity|inhibition of RNA synthetase activity|down regulation of PB1 proteins|down regulation of PB2 proteins|down regulation of RDRP|downregulation of transcriptase|down regulation of ribonucleic synthetase activity|inhibition of RNA-dependent RNA polymerase activity|negative regulation of Q-beta replicase activity|down-regulation of Q-beta replicase activity|down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|down regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of RNA-dependent RNA replicase activity|negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down-regulation of 3D polymerase activity|negative regulation of 3D polymerase activity|negative regulation of ribonucleic replicase activity|downregulation of ribonucleic synthetase activity|down-regulation of ribonucleic replicase activity|negative regulation of RNA nucleotidyltransferase (RNA-directed) activity|down-regulation of RNA nucleotidyltransferase (RNA-directed) activity|downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|inhibition of polymerase L|downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of RNA synthetase activity|inhibition of PB1 proteins|inhibition of PB2 proteins|down regulation of RNA-dependent RNA polymerase activity|inhibition of RDRP|downregulation of RNA replicase activity|down-regulation of ribonucleic acid replicase activity|negative regulation of ribonucleic acid replicase activity|downregulation of RNA-directed RNA polymerase activity|inhibition of RNA-dependent RNA replicase activity|down-regulation of transcriptase|negative regulation of transcriptase|down-regulation of phage f2 replicase|downregulation of RNA synthetase activity|negative regulation of phage f2 replicase|downregulation of RNA-dependent RNA polymerase activity|down regulation of RNA replicase activity|downregulation of 3D polymerase activity|down regulation of RNA-directed RNA polymerase activity|down-regulation of ribonucleic synthetase activity|downregulation of ribonucleic replicase activity|inhibition of Q-beta replicase activity|negative regulation of ribonucleic synthetase activity|inhibition of RNA-directed RNA polymerase activity|negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|downregulation of RNA nucleotidyltransferase (RNA-directed) activity|inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity|downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of 3D polymerase activity|down regulation of ribonucleic replicase activity|inhibition of RNA replicase activity|negative regulation of PB1 proteins|down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down regulation of RNA nucleotidyltransferase (RNA-directed) activity|negative regulation of polymerase L|down-regulation of PB1 proteins|down-regulation of polymerase L|negative regulation of RNA synthetase activity|down-regulation of RNA synthetase activity|down-regulation of RDRP|negative regulation of PB2 proteins|downregulation of phage f2 replicase|inhibition of ribonucleic acid replicase activity|down-regulation of PB2 proteins|negative regulation of RDRP|negative regulation of RNA-dependent RNA polymerase activity|down-regulation of RNA-dependent RNA polymerase activity|down regulation of Q-beta replicase activity|down-regulation of RNA-dependent RNA replicase activity|inhibition of transcriptase|negative regulation of RNA-dependent RNA replicase activity|down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of phage f2 replicase|inhibition of 3D polymerase activity http://purl.obolibrary.org/obo/GO_1900260 GO:1900262 biolink:BiologicalProcess regulation of DNA-directed DNA polymerase activity Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity. go-plus.json regulation of eta DNA polymerase activity|regulation of DNA polymerase II|regulation of DNA polymerase alpha|regulation of deoxyribonucleic polymerase I|regulation of Taq DNA polymerase|regulation of DNA replicase activity|regulation of mu DNA polymerase activity|regulation of lambda DNA polymerase activity|regulation of nu DNA polymerase activity|regulation of DNA duplicase activity|regulation of kappa DNA polymerase activity|regulation of epsilon DNA polymerase activity|regulation of DNA polymerase V activity|regulation of sequenase|regulation of sigma DNA polymerase activity|regulation of DNA-dependent DNA polymerase activity|regulation of deoxyribonucleic acid duplicase activity|regulation of deoxyribonucleic duplicase activity|regulation of Tca DNA polymerase|regulation of DNA polymerase beta|regulation of zeta DNA polymerase activity|regulation of alpha DNA polymerase activity|regulation of theta DNA polymerase activity|regulation of Klenow fragment|regulation of gamma DNA-directed DNA polymerase activity|regulation of DNA polymerase III|regulation of DNA polymerase I|regulation of duplicase|regulation of DNA polymerase gamma|regulation of iota DNA polymerase activity|regulation of Taq Pol I|regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|regulation of delta DNA polymerase activity|regulation of beta DNA polymerase activity|regulation of DNA nucleotidyltransferase (DNA-directed) activity http://purl.obolibrary.org/obo/GO_1900262 GO:1900261 biolink:BiologicalProcess positive regulation of RNA-directed 5'-3' RNA polymerase activity Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity. go-plus.json positive regulation of PB2 proteins|positive regulation of RDRP|up-regulation of RNA replicase activity|upregulation of ribonucleic acid replicase activity|up regulation of polymerase L|up-regulation of RNA-directed RNA polymerase activity|upregulation of transcriptase|up regulation of PB1 proteins|up regulation of PB2 proteins|positive regulation of RNA-dependent RNA replicase activity|activation of RNA-directed RNA polymerase activity|up regulation of RDRP|upregulation of phage f2 replicase|up-regulation of RNA synthetase activity|up regulation of Q-beta replicase activity|up regulation of RNA-dependent RNA replicase activity|up-regulation of RNA-dependent RNA polymerase activity|up-regulation of 3D polymerase activity|up regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of Q-beta replicase activity|upregulation of ribonucleic synthetase activity|up-regulation of ribonucleic replicase activity|activation of RNA replicase activity|up-regulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|positive regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|positive regulation of RNA-directed RNA polymerase activity|up regulation of ribonucleic acid replicase activity|activation of Q-beta replicase activity|upregulation of PB1 proteins|positive regulation of RNA replicase activity|upregulation of polymerase L|activation of 3D polymerase activity|up regulation of transcriptase|upregulation of RDRP|activation of ribonucleic replicase activity|upregulation of PB2 proteins|positive regulation of ribonucleic acid replicase activity|up-regulation of phage f2 replicase|activation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of RNA synthetase activity|positive regulation of transcriptase|up regulation of RNA replicase activity|activation of RNA nucleotidyltransferase (RNA-directed) activity|activation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of RNA-dependent RNA polymerase activity|up regulation of RNA-directed RNA polymerase activity|upregulation of RNA-dependent RNA replicase activity|up regulation of ribonucleic synthetase activity|positive regulation of 3D polymerase activity|up-regulation of Q-beta replicase activity|up regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|activation of ribonucleic acid replicase activity|positive regulation of ribonucleic replicase activity|up regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of 3D polymerase activity|positive regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|activation of transcriptase|positive regulation of ribonucleic synthetase activity|activation of phage f2 replicase|up-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of RNA nucleotidyltransferase (RNA-directed) activity|up regulation of ribonucleic replicase activity|positive regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|up-regulation of PB1 proteins|positive regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up-regulation of polymerase L|up regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up regulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of PB2 proteins|up-regulation of RDRP|up regulation of RNA synthetase activity|up-regulation of ribonucleic acid replicase activity|up-regulation of RNA-dependent RNA replicase activity|up regulation of RNA-dependent RNA polymerase activity|upregulation of RNA replicase activity|activation of ribonucleic synthetase activity|positive regulation of phage f2 replicase|up-regulation of transcriptase|positive regulation of RNA synthetase activity|upregulation of RNA-directed RNA polymerase activity|activation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|positive regulation of RNA-dependent RNA polymerase activity|activation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of phage f2 replicase|upregulation of Q-beta replicase activity|activation of PB1 proteins|activation of polymerase L|activation of RDRP|activation of PB2 proteins|upregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of 3D polymerase activity|upregulation of ribonucleic replicase activity|up-regulation of ribonucleic synthetase activity|activation of RNA synthetase activity|activation of RNA-dependent RNA replicase activity|activation of RNA-dependent RNA polymerase activity|upregulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|upregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|positive regulation of polymerase L|up-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|positive regulation of PB1 proteins http://purl.obolibrary.org/obo/GO_1900261 GO:0046190 biolink:BiologicalProcess aerobic phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. go-plus.json aerobic phenol-containing compound biosynthesis|aerobic phenol-containing compound anabolism|aerobic phenol-containing compound synthesis|aerobic phenol-containing compound formation http://purl.obolibrary.org/obo/GO_0046190 GO:0071149 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071149 GO:0071148 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071148 GO:0071147 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071147 GO:0071146 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071146 GO:0071145 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071145 GO:0071144 biolink:CellularComponent heteromeric SMAD protein complex A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric. go-plus.json SMAD2-SMAD3-SMAD4 protein complex|SMAD3-SMAD4 protein complex|SMAD1-SMAD4 protein complex|SMAD2-SMAD4 protein complex http://purl.obolibrary.org/obo/GO_0071144 GO:0071132 biolink:CellularComponent alphaX-beta2 integrin-ICAM-4 complex A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4. go-plus.json ITGAX-ITGB2-ICAM4 complex http://purl.obolibrary.org/obo/GO_0071132 GO:0046198 biolink:BiologicalProcess obsolete cresol biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote. go-plus.json cresol anabolism|cresol biosynthetic process|cresol biosynthesis|cresol synthesis|cresol formation http://purl.obolibrary.org/obo/GO_0046198 GO:0071131 biolink:CellularComponent alphaV-beta3 integrin-laminin alpha-4 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4. go-plus.json ITGAV-ITGB3-LAMA4 complex http://purl.obolibrary.org/obo/GO_0071131 GO:0046197 biolink:BiologicalProcess orcinol biosynthetic process The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants. go-plus.json orcinol anabolism|orcinol synthesis|orcinol formation|orcinol biosynthesis http://purl.obolibrary.org/obo/GO_0046197 GO:0046196 biolink:BiologicalProcess 4-nitrophenol catabolic process The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion. go-plus.json 4-nitrophenol degradation|4-nitrophenol breakdown|4-nitrophenol catabolism http://purl.obolibrary.org/obo/GO_0046196 GO:0071130 biolink:CellularComponent alpha5-beta1 integrin-LPP3 complex A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3. go-plus.json ITGA5-ITGB1-PPAP2B complex http://purl.obolibrary.org/obo/GO_0071130 GO:0046195 biolink:BiologicalProcess obsolete 4-nitrophenol biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion. go-plus.json 4-nitrophenol anabolism|4-nitrophenol biosynthesis|4-nitrophenol biosynthetic process|4-nitrophenol synthesis|4-nitrophenol formation http://purl.obolibrary.org/obo/GO_0046195 GO:0046194 biolink:BiologicalProcess obsolete pentachlorophenol biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms. go-plus.json pentachlorophenol biosynthesis|pentachlorophenol biosynthetic process|pentachlorophenol anabolism|pentachlorophenol synthesis|pentachlorophenol formation http://purl.obolibrary.org/obo/GO_0046194 GO:0046193 biolink:BiologicalProcess anaerobic phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen. go-plus.json anaerobic phenol-containing compound breakdown|anaerobic phenol-containing compound catabolism|anaerobic phenol-containing compound degradation http://purl.obolibrary.org/obo/GO_0046193 GO:0046192 biolink:BiologicalProcess anaerobic phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen. go-plus.json anaerobic phenol-containing compound anabolism|anaerobic phenol-containing compound synthesis|anaerobic phenol-containing compound formation|anaerobic phenol-containing compound biosynthesis http://purl.obolibrary.org/obo/GO_0046192 GO:0046191 biolink:BiologicalProcess aerobic phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. go-plus.json aerobic phenol-containing compound catabolism|aerobic phenol-containing compound degradation|aerobic phenol-containing compound breakdown http://purl.obolibrary.org/obo/GO_0046191 GO:1900268 biolink:BiologicalProcess regulation of reverse transcription Any process that modulates the frequency, rate or extent of reverse transcription. go-plus.json http://purl.obolibrary.org/obo/GO_1900268 GO:1900267 biolink:BiologicalProcess positive regulation of substance P receptor binding Any process that activates or increases the frequency, rate or extent of substance P receptor binding. go-plus.json activation of substance P receptor binding|up-regulation of substance P receptor binding|activation of neurokinin-1 receptor binding|up regulation of substance P receptor ligand|up-regulation of neurokinin-1 receptor binding|positive regulation of substance P receptor ligand|up regulation of substance P receptor binding|activation of substance P receptor ligand|upregulation of neurokinin-1 receptor binding|up-regulation of substance P receptor ligand|upregulation of substance P receptor binding|up regulation of neurokinin-1 receptor binding|upregulation of substance P receptor ligand|positive regulation of neurokinin-1 receptor binding http://purl.obolibrary.org/obo/GO_1900267 GO:1900269 biolink:BiologicalProcess negative regulation of reverse transcription Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription. go-plus.json down regulation of reverse transcription|downregulation of reverse transcription|down-regulation of reverse transcription|inhibition of reverse transcription http://purl.obolibrary.org/obo/GO_1900269 GO:1900264 biolink:BiologicalProcess positive regulation of DNA-directed DNA polymerase activity Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity. go-plus.json up regulation of delta DNA polymerase activity|up-regulation of Tca DNA polymerase|up-regulation of sigma DNA polymerase activity|up regulation of mu DNA polymerase activity|up regulation of DNA replicase activity|upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of DNA duplicase activity|activation of alpha DNA polymerase activity|up regulation of nu DNA polymerase activity|activation of theta DNA polymerase activity|up-regulation of DNA-dependent DNA polymerase activity|up regulation of lambda DNA polymerase activity|positive regulation of Taq Pol I|activation of Klenow fragment|up regulation of DNA duplicase activity|up-regulation of DNA-directed DNA polymerase activity|upregulation of beta DNA polymerase activity|positive regulation of delta DNA polymerase activity|upregulation of kappa DNA polymerase activity|activation of DNA-directed DNA polymerase activity|upregulation of DNA nucleotidyltransferase (DNA-directed) activity|up-regulation of zeta DNA polymerase activity|upregulation of epsilon DNA polymerase activity|up-regulation of deoxyribonucleic duplicase activity|activation of duplicase|upregulation of DNA polymerase V activity|up-regulation of gamma DNA-directed DNA polymerase activity|up-regulation of DNA polymerase beta|activation of deoxyribonucleic acid duplicase activity|up-regulation of DNA polymerase III|up-regulation of DNA polymerase I|upregulation of sequenase|activation of Taq Pol I|activation of Tca DNA polymerase|up regulation of eta DNA polymerase activity|up regulation of DNA polymerase II|up-regulation of theta DNA polymerase activity|upregulation of DNA polymerase alpha|activation of delta DNA polymerase activity|up-regulation of DNA polymerase gamma|up-regulation of alpha DNA polymerase activity|up regulation of deoxyribonucleic polymerase I|up-regulation of Klenow fragment|positive regulation of eta DNA polymerase activity|up-regulation of iota DNA polymerase activity|upregulation of sigma DNA polymerase activity|positive regulation of DNA polymerase II|activation of zeta DNA polymerase activity|upregulation of Taq DNA polymerase|positive regulation of deoxyribonucleic polymerase I|up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|activation of gamma DNA-directed DNA polymerase activity|upregulation of DNA replicase activity|upregulation of mu DNA polymerase activity|up-regulation of duplicase|positive regulation of deoxyribonucleic acid duplicase activity|upregulation of DNA-dependent DNA polymerase activity|up-regulation of beta DNA polymerase activity|upregulation of lambda DNA polymerase activity|activation of DNA polymerase III|activation of DNA polymerase I|upregulation of nu DNA polymerase activity|positive regulation of Tca DNA polymerase|up-regulation of Taq Pol I|up-regulation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of deoxyribonucleic acid duplicase activity|upregulation of DNA duplicase activity|up regulation of kappa DNA polymerase activity|up regulation of Tca DNA polymerase|up-regulation of delta DNA polymerase activity|upregulation of DNA polymerase beta|activation of DNA polymerase gamma|upregulation of deoxyribonucleic duplicase activity|activation of eta DNA polymerase activity|activation of iota DNA polymerase activity|activation of deoxyribonucleic polymerase I|up regulation of DNA polymerase V activity|activation of DNA polymerase II|up regulation of epsilon DNA polymerase activity|positive regulation of zeta DNA polymerase activity|positive regulation of gamma DNA-directed DNA polymerase activity|up regulation of DNA-directed DNA polymerase activity|up regulation of sequenase|positive regulation of kappa DNA polymerase activity|activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up regulation of zeta DNA polymerase activity|positive regulation of DNA polymerase III|positive regulation of DNA polymerase I|positive regulation of epsilon DNA polymerase activity|positive regulation of DNA polymerase V activity|up-regulation of DNA polymerase alpha|upregulation of alpha DNA polymerase activity|upregulation of theta DNA polymerase activity|positive regulation of sequenase|up regulation of gamma DNA-directed DNA polymerase activity|upregulation of Klenow fragment|activation of beta DNA polymerase activity|activation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of DNA polymerase III|positive regulation of DNA polymerase gamma|up-regulation of Taq DNA polymerase|up regulation of DNA polymerase I|up regulation of sigma DNA polymerase activity|upregulation of duplicase|up-regulation of DNA replicase activity|up-regulation of eta DNA polymerase activity|positive regulation of iota DNA polymerase activity|up-regulation of mu DNA polymerase activity|up-regulation of deoxyribonucleic polymerase I|up-regulation of lambda DNA polymerase activity|up regulation of DNA-dependent DNA polymerase activity|up regulation of DNA polymerase gamma|up-regulation of nu DNA polymerase activity|up-regulation of DNA polymerase II|activation of kappa DNA polymerase activity|positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|upregulation of Taq Pol I|up regulation of iota DNA polymerase activity|up-regulation of DNA duplicase activity|activation of DNA polymerase V activity|activation of epsilon DNA polymerase activity|positive regulation of sigma DNA polymerase activity|upregulation of delta DNA polymerase activity|upregulation of deoxyribonucleic acid duplicase activity|positive regulation of beta DNA polymerase activity|activation of DNA polymerase alpha|activation of sequenase|up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of DNA-dependent DNA polymerase activity|positive regulation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of deoxyribonucleic duplicase activity|up regulation of DNA polymerase beta|upregulation of Tca DNA polymerase|activation of Taq DNA polymerase|up regulation of beta DNA polymerase activity|up regulation of DNA nucleotidyltransferase (DNA-directed) activity|positive regulation of DNA polymerase beta|positive regulation of deoxyribonucleic duplicase activity|upregulation of DNA-directed DNA polymerase activity|activation of mu DNA polymerase activity|activation of DNA replicase activity|upregulation of zeta DNA polymerase activity|up-regulation of kappa DNA polymerase activity|activation of sigma DNA polymerase activity|up regulation of alpha DNA polymerase activity|activation of nu DNA polymerase activity|activation of lambda DNA polymerase activity|up regulation of theta DNA polymerase activity|activation of DNA-dependent DNA polymerase activity|activation of DNA duplicase activity|up regulation of Klenow fragment|up-regulation of DNA polymerase V activity|positive regulation of DNA polymerase alpha|upregulation of gamma DNA-directed DNA polymerase activity|up-regulation of epsilon DNA polymerase activity|positive regulation of alpha DNA polymerase activity|upregulation of eta DNA polymerase activity|upregulation of DNA polymerase III|up-regulation of sequenase|positive regulation of theta DNA polymerase activity|upregulation of DNA polymerase I|upregulation of DNA polymerase II|up regulation of DNA polymerase alpha|up regulation of duplicase|positive regulation of Taq DNA polymerase|positive regulation of Klenow fragment|upregulation of deoxyribonucleic polymerase I|activation of deoxyribonucleic duplicase activity|positive regulation of DNA replicase activity|upregulation of DNA polymerase gamma|activation of DNA polymerase beta|positive regulation of mu DNA polymerase activity|up regulation of Taq Pol I|positive regulation of duplicase|upregulation of iota DNA polymerase activity|positive regulation of lambda DNA polymerase activity|up-regulation of deoxyribonucleic acid duplicase activity|positive regulation of nu DNA polymerase activity|up regulation of Taq DNA polymerase http://purl.obolibrary.org/obo/GO_1900264 GO:1900263 biolink:BiologicalProcess negative regulation of DNA-directed DNA polymerase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity. go-plus.json down regulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of Klenow fragment|negative regulation of Klenow fragment|downregulation of Taq DNA polymerase|inhibition of DNA polymerase gamma|inhibition of sequenase|downregulation of eta DNA polymerase activity|downregulation of mu DNA polymerase activity|inhibition of iota DNA polymerase activity|downregulation of nu DNA polymerase activity|down-regulation of duplicase|negative regulation of duplicase|downregulation of DNA polymerase II|downregulation of DNA replicase activity|downregulation of lambda DNA polymerase activity|downregulation of deoxyribonucleic polymerase I|down regulation of DNA polymerase alpha|inhibition of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of sigma DNA polymerase activity|down-regulation of Taq Pol I|negative regulation of Taq Pol I|down regulation of kappa DNA polymerase activity|inhibition of beta DNA polymerase activity|down-regulation of delta DNA polymerase activity|negative regulation of delta DNA polymerase activity|down regulation of Taq DNA polymerase|downregulation of DNA duplicase activity|down regulation of mu DNA polymerase activity|negative regulation of Tca DNA polymerase|negative regulation of deoxyribonucleic acid duplicase activity|down-regulation of deoxyribonucleic acid duplicase activity|down-regulation of Tca DNA polymerase|down regulation of epsilon DNA polymerase activity|down regulation of DNA polymerase V activity|inhibition of DNA-dependent DNA polymerase activity|inhibition of DNA nucleotidyltransferase (DNA-directed) activity|down regulation of nu DNA polymerase activity|down regulation of lambda DNA polymerase activity|down regulation of DNA replicase activity|down regulation of sequenase|inhibition of DNA polymerase beta|down-regulation of DNA-directed DNA polymerase activity|downregulation of kappa DNA polymerase activity|negative regulation of zeta DNA polymerase activity|inhibition of deoxyribonucleic duplicase activity|down regulation of DNA duplicase activity|down-regulation of zeta DNA polymerase activity|down-regulation of gamma DNA-directed DNA polymerase activity|inhibition of DNA polymerase alpha|negative regulation of gamma DNA-directed DNA polymerase activity|downregulation of DNA polymerase V activity|downregulation of epsilon DNA polymerase activity|down regulation of sigma DNA polymerase activity|inhibition of alpha DNA polymerase activity|down-regulation of DNA polymerase III|negative regulation of eta DNA polymerase activity|negative regulation of DNA polymerase I|inhibition of theta DNA polymerase activity|down-regulation of eta DNA polymerase activity|negative regulation of DNA polymerase III|down-regulation of DNA polymerase I|down-regulation of deoxyribonucleic polymerase I|down-regulation of DNA polymerase II|negative regulation of deoxyribonucleic polymerase I|inhibition of Klenow fragment|downregulation of sequenase|inhibition of Taq DNA polymerase|negative regulation of DNA polymerase II|inhibition of mu DNA polymerase activity|down regulation of DNA-dependent DNA polymerase activity|negative regulation of DNA polymerase gamma|down-regulation of DNA polymerase gamma|inhibition of DNA replicase activity|negative regulation of iota DNA polymerase activity|inhibition of lambda DNA polymerase activity|down-regulation of iota DNA polymerase activity|inhibition of nu DNA polymerase activity|downregulation of deoxyribonucleic acid duplicase activity|downregulation of sigma DNA polymerase activity|downregulation of Tca DNA polymerase|inhibition of duplicase|down regulation of DNA polymerase beta|down-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|negative regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of DNA duplicase activity|down regulation of deoxyribonucleic duplicase activity|inhibition of Taq Pol I|down-regulation of beta DNA polymerase activity|downregulation of DNA-dependent DNA polymerase activity|negative regulation of beta DNA polymerase activity|inhibition of delta DNA polymerase activity|down-regulation of kappa DNA polymerase activity|negative regulation of kappa DNA polymerase activity|down regulation of alpha DNA polymerase activity|downregulation of DNA-directed DNA polymerase activity|downregulation of zeta DNA polymerase activity|down regulation of theta DNA polymerase activity|downregulation of gamma DNA-directed DNA polymerase activity|down-regulation of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of DNA polymerase V activity|negative regulation of epsilon DNA polymerase activity|down regulation of Tca DNA polymerase|down-regulation of DNA polymerase V activity|down-regulation of epsilon DNA polymerase activity|down regulation of Klenow fragment|downregulation of DNA polymerase beta|down regulation of deoxyribonucleic acid duplicase activity|negative regulation of DNA nucleotidyltransferase (DNA-directed) activity|downregulation of DNA polymerase I|downregulation of DNA polymerase III|downregulation of deoxyribonucleic duplicase activity|down-regulation of sequenase|negative regulation of sequenase|down-regulation of DNA polymerase alpha|negative regulation of DNA polymerase alpha|down regulation of DNA-directed DNA polymerase activity|downregulation of DNA polymerase gamma|down regulation of zeta DNA polymerase activity|downregulation of alpha DNA polymerase activity|downregulation of theta DNA polymerase activity|down regulation of duplicase|down regulation of gamma DNA-directed DNA polymerase activity|inhibition of DNA-directed DNA polymerase activity|downregulation of iota DNA polymerase activity|down regulation of Taq Pol I|downregulation of Klenow fragment|inhibition of eta DNA polymerase activity|down regulation of delta DNA polymerase activity|down regulation of DNA polymerase III|down-regulation of sigma DNA polymerase activity|negative regulation of sigma DNA polymerase activity|down regulation of DNA polymerase I|negative regulation of Taq DNA polymerase|inhibition of DNA polymerase II|inhibition of deoxyribonucleic polymerase I|down-regulation of Taq DNA polymerase|negative regulation of mu DNA polymerase activity|down-regulation of mu DNA polymerase activity|downregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of Tca DNA polymerase|downregulation of beta DNA polymerase activity|inhibition of deoxyribonucleic acid duplicase activity|down-regulation of DNA-dependent DNA polymerase activity|down regulation of DNA polymerase gamma|down-regulation of lambda DNA polymerase activity|negative regulation of nu DNA polymerase activity|down-regulation of nu DNA polymerase activity|down-regulation of DNA replicase activity|downregulation of duplicase|negative regulation of DNA replicase activity|negative regulation of DNA-dependent DNA polymerase activity|negative regulation of lambda DNA polymerase activity|down regulation of iota DNA polymerase activity|downregulation of Taq Pol I|negative regulation of DNA duplicase activity|downregulation of delta DNA polymerase activity|negative regulation of DNA polymerase beta|down-regulation of DNA polymerase beta|downregulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of DNA duplicase activity|negative regulation of deoxyribonucleic duplicase activity|down-regulation of deoxyribonucleic duplicase activity|inhibition of zeta DNA polymerase activity|down regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of gamma DNA-directed DNA polymerase activity|down regulation of eta DNA polymerase activity|inhibition of kappa DNA polymerase activity|down regulation of beta DNA polymerase activity|negative regulation of theta DNA polymerase activity|inhibition of DNA polymerase III|down-regulation of alpha DNA polymerase activity|down regulation of DNA polymerase II|inhibition of DNA polymerase V activity|negative regulation of alpha DNA polymerase activity|inhibition of DNA polymerase I|down regulation of deoxyribonucleic polymerase I|inhibition of epsilon DNA polymerase activity|downregulation of DNA polymerase alpha|down-regulation of theta DNA polymerase activity http://purl.obolibrary.org/obo/GO_1900263 GO:1900266 biolink:BiologicalProcess negative regulation of substance P receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding. go-plus.json down regulation of substance P receptor ligand|down-regulation of neurokinin-1 receptor binding|negative regulation of neurokinin-1 receptor binding|downregulation of substance P receptor ligand|down-regulation of substance P receptor binding|inhibition of neurokinin-1 receptor binding|negative regulation of substance P receptor ligand|down-regulation of substance P receptor ligand|downregulation of substance P receptor binding|down regulation of substance P receptor binding|down regulation of neurokinin-1 receptor binding|inhibition of substance P receptor binding|downregulation of neurokinin-1 receptor binding|inhibition of substance P receptor ligand http://purl.obolibrary.org/obo/GO_1900266 GO:0046199 biolink:BiologicalProcess cresol catabolic process The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote. go-plus.json cresol degradation|cresol breakdown|cresol catabolism http://purl.obolibrary.org/obo/GO_0046199 GO:1900265 biolink:BiologicalProcess regulation of substance P receptor binding Any process that modulates the frequency, rate or extent of substance P receptor binding. go-plus.json regulation of substance P receptor ligand|regulation of neurokinin-1 receptor binding http://purl.obolibrary.org/obo/GO_1900265 GO:1900271 biolink:BiologicalProcess regulation of long-term synaptic potentiation Any process that modulates the frequency, rate or extent of long-term synaptic potentiation. go-plus.json regulation of LTP|regulation of long-term potentiation http://purl.obolibrary.org/obo/GO_1900271 GO:1900270 biolink:BiologicalProcess positive regulation of reverse transcription Any process that activates or increases the frequency, rate or extent of reverse transcription. go-plus.json up-regulation of reverse transcription|upregulation of reverse transcription|up regulation of reverse transcription|activation of reverse transcription http://purl.obolibrary.org/obo/GO_1900270 GO:1900273 biolink:BiologicalProcess positive regulation of long-term synaptic potentiation Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation. go-plus.json positive regulation of long-term potentiation|up regulation of long-term potentiation|up regulation of long-term synaptic potentiation|activation of long-term synaptic potentiation|up regulation of LTP|positive regulation of LTP|upregulation of long-term potentiation|activation of LTP|up-regulation of long-term synaptic potentiation|up-regulation of long-term potentiation|up-regulation of LTP|upregulation of long-term synaptic potentiation|activation of long-term potentiation|upregulation of LTP http://purl.obolibrary.org/obo/GO_1900273 GO:1900272 biolink:BiologicalProcess negative regulation of long-term synaptic potentiation Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation. go-plus.json downregulation of long-term synaptic potentiation|down regulation of LTP|downregulation of long-term potentiation|downregulation of LTP|down-regulation of long-term synaptic potentiation|down regulation of long-term potentiation|negative regulation of LTP|down-regulation of LTP|inhibition of long-term potentiation|inhibition of long-term synaptic potentiation|inhibition of LTP|negative regulation of long-term potentiation|down regulation of long-term synaptic potentiation|down-regulation of long-term potentiation http://purl.obolibrary.org/obo/GO_1900272 GO:0071139 biolink:BiologicalProcess resolution of recombination intermediates The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged. go-plus.json http://purl.obolibrary.org/obo/GO_0071139 GO:0071138 biolink:CellularComponent alpha5-beta5-fibronectin-SFRP2 complex A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2. go-plus.json ITGA5-ITGB5-FN-1-SFRP2 complex http://purl.obolibrary.org/obo/GO_0071138 GO:0071137 biolink:CellularComponent alphaV-beta3 integrin-CD98 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98. go-plus.json ITGAV-ITGB3-SLC3A2 complex http://purl.obolibrary.org/obo/GO_0071137 GO:0071136 biolink:CellularComponent alpha7-beta1 integrin-laminin alpha-2 complex A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2. go-plus.json ITGA7-ITGB1-LAMA2 complex http://purl.obolibrary.org/obo/GO_0071136 GO:0071135 biolink:CellularComponent alpha7-beta1 integrin-focal adhesion kinase complex A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase. go-plus.json ITGA7-ITGB1-PTK2 complex http://purl.obolibrary.org/obo/GO_0071135 GO:0071134 biolink:CellularComponent alpha9-beta1 integrin-thrombospondin-1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1. go-plus.json ITGA9-ITGB1-THBS1 complex http://purl.obolibrary.org/obo/GO_0071134 GO:0071133 biolink:CellularComponent alpha9-beta1 integrin-ADAM8 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8. go-plus.json ITGA9-ITGB1-ADAM8 complex http://purl.obolibrary.org/obo/GO_0071133 GO:0071165 biolink:BiologicalProcess GINS complex assembly The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks. go-plus.json http://purl.obolibrary.org/obo/GO_0071165 GO:0071164 biolink:MolecularActivity RNA trimethylguanosine synthase activity Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine. go-plus.json snRNA methyltransferase activity|cap hypermethylase activity|small nuclear RNA methyltransferase activity http://purl.obolibrary.org/obo/GO_0071164 GO:0071163 biolink:BiologicalProcess DNA replication preinitiation complex assembly The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity. go-plus.json pre-IC complex assembly|DNA replication preinitiation complex formation http://purl.obolibrary.org/obo/GO_0071163 GO:0071162 biolink:CellularComponent CMG complex A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. go-plus.json unwindosome http://purl.obolibrary.org/obo/GO_0071162 GO:0071161 biolink:MolecularActivity cyanophycin synthetase activity (L-arginine-adding) Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1. RHEA:23888|EC:6.3.2.30 go-plus.json http://purl.obolibrary.org/obo/GO_0071161 GO:0071160 biolink:MolecularActivity cyanophycin synthetase activity (L-aspartate-adding) Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp. EC:6.3.2.29|RHEA:13277 go-plus.json http://purl.obolibrary.org/obo/GO_0071160 GO:1900279 biolink:BiologicalProcess regulation of CD4-positive, alpha-beta T cell costimulation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. go-plus.json regulation of CD4-positive, alpha beta T cell costimulation http://purl.obolibrary.org/obo/GO_1900279 GO:1900278 biolink:BiologicalProcess positive regulation of proteinase activated receptor activity Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity. go-plus.json up regulation of proteinase activated receptor activity|upregulation of proteinase activated receptor activity|up-regulation of proteinase activated receptor activity|activation of proteinase activated receptor activity http://purl.obolibrary.org/obo/GO_1900278 GO:1900275 biolink:BiologicalProcess negative regulation of phospholipase C activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity. go-plus.json down regulation of lipophosphodiesterase C|negative regulation of phosphatidase C|down-regulation of phosphatidase C|down-regulation of phospholipase C activity|downregulation of lipophosphodiesterase C|down-regulation of lecithinase C activity|negative regulation of lecithinase C activity|downregulation of phospholipase C activity|inhibition of phosphatidase C|down-regulation of lipophosphodiesterase C|negative regulation of lipophosphodiesterase C|down regulation of phospholipase C activity|inhibition of phospholipase C activity|downregulation of lecithinase C activity|down regulation of phosphatidase C|down regulation of lecithinase C activity|downregulation of phosphatidase C|inhibition of lipophosphodiesterase C|inhibition of lecithinase C activity http://purl.obolibrary.org/obo/GO_1900275 GO:1900274 biolink:BiologicalProcess regulation of phospholipase C activity Any process that modulates the frequency, rate or extent of phospholipase C activity. go-plus.json regulation of lipophosphodiesterase C|regulation of lecithinase C activity|regulation of phosphatidase C http://purl.obolibrary.org/obo/GO_1900274 GO:1900277 biolink:BiologicalProcess negative regulation of proteinase activated receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity. go-plus.json down-regulation of proteinase activated receptor activity|downregulation of proteinase activated receptor activity|down regulation of proteinase activated receptor activity|inhibition of proteinase activated receptor activity http://purl.obolibrary.org/obo/GO_1900277 GO:1900276 biolink:BiologicalProcess regulation of proteinase activated receptor activity Any process that modulates the frequency, rate or extent of proteinase activated receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_1900276 GO:1900282 biolink:BiologicalProcess regulation of cellobiose catabolic process Any process that modulates the frequency, rate or extent of cellobiose catabolic process. go-plus.json regulation of cellobiose catabolism http://purl.obolibrary.org/obo/GO_1900282 GO:1900281 biolink:BiologicalProcess positive regulation of CD4-positive, alpha-beta T cell costimulation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. go-plus.json up-regulation of CD4-positive, alpha beta T cell costimulation|positive regulation of CD4-positive, alpha beta T cell costimulation|upregulation of CD4-positive, alpha beta T cell costimulation|up regulation of CD4-positive, alpha beta T cell costimulation|activation of CD4-positive, alpha beta T cell costimulation http://purl.obolibrary.org/obo/GO_1900281 GO:1900284 biolink:BiologicalProcess positive regulation of cellobiose catabolic process Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process. go-plus.json up regulation of cellobiose catabolic process|up-regulation of cellobiose catabolism|upregulation of cellobiose catabolic process|upregulation of cellobiose catabolism|up-regulation of cellobiose catabolic process|activation of cellobiose catabolic process|up regulation of cellobiose catabolism|activation of cellobiose catabolism|positive regulation of cellobiose catabolism http://purl.obolibrary.org/obo/GO_1900284 GO:1900283 biolink:BiologicalProcess negative regulation of cellobiose catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process. go-plus.json downregulation of cellobiose catabolic process|inhibition of cellobiose catabolism|down regulation of cellobiose catabolic process|inhibition of cellobiose catabolic process|down regulation of cellobiose catabolism|downregulation of cellobiose catabolism|down-regulation of cellobiose catabolic process|negative regulation of cellobiose catabolism|down-regulation of cellobiose catabolism http://purl.obolibrary.org/obo/GO_1900283 GO:1900280 biolink:BiologicalProcess negative regulation of CD4-positive, alpha-beta T cell costimulation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. go-plus.json inhibition of CD4-positive, alpha beta T cell costimulation|negative regulation of CD4-positive, alpha beta T cell costimulation|down regulation of CD4-positive, alpha beta T cell costimulation|downregulation of CD4-positive, alpha beta T cell costimulation|down-regulation of CD4-positive, alpha beta T cell costimulation http://purl.obolibrary.org/obo/GO_1900280 GO:0071169 biolink:BiologicalProcess establishment of protein localization to chromatin The directed movement of a protein to a part of a chromosome that is organized into chromatin. go-plus.json establishment of protein localisation to chromatin http://purl.obolibrary.org/obo/GO_0071169 GO:0071168 biolink:BiologicalProcess protein localization to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. go-plus.json protein localisation to chromatin http://purl.obolibrary.org/obo/GO_0071168 GO:0071167 biolink:BiologicalProcess obsolete ribonucleoprotein complex import into nucleus OBSOLETE. The directed movement of a ribonucleoprotein complex from the cytoplasm to the nucleus. go-plus.json RNP import into nucleus|ribonucleoprotein complex nucleus import|ribonucleoprotein complex transport from cytoplasm to nucleus|ribonucleoprotein import into nucleus|ribonucleoprotein complex targeting to nucleus|ribonucleoprotein complex import into cell nucleus http://purl.obolibrary.org/obo/GO_0071167 GO:0071166 biolink:BiologicalProcess ribonucleoprotein complex localization Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell. go-plus.json cellular ribonucleoprotein complex localization|establishment and maintenance of ribonucleoprotein complex localization|ribonucleoprotein complex localisation|RNP localization http://purl.obolibrary.org/obo/GO_0071166 GO:0071154 biolink:CellularComponent G-protein alpha(i)1-synembrin complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein. go-plus.json Ric-8A G(i) alpha-2 subunit complex|Ric-8A G(i) alpha-1 subunit complex http://purl.obolibrary.org/obo/GO_0071154 GO:0071153 biolink:CellularComponent G-protein alpha(o)-synembrin complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein. go-plus.json Ric-8A G(o) alpha-1 subunit complex|Ric-8A G(o) alpha-2 subunit complex http://purl.obolibrary.org/obo/GO_0071153 GO:0071152 biolink:CellularComponent G-protein alpha(q)-synembrin complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein. go-plus.json Ric-8A G(q) alpha subunit complex http://purl.obolibrary.org/obo/GO_0071152 GO:0071151 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071151 GO:0071150 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071150 UBERON:0036066 biolink:AnatomicalEntity inferior endocardial cushion The endocardial cushion that forms on the ventral surface of the AV canal. go-plus.json ventral endocardial cushion http://purl.obolibrary.org/obo/UBERON_0036066 GO:1900289 biolink:BiologicalProcess negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. go-plus.json inhibition of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|inhibition of coenzyme F420-dependent nitroimidazole catabolism|down regulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole breakdown|negative regulation of coenzyme F420-dependent nitroimidazole reduction|down-regulation of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|negative regulation of coenzyme F420-dependent nitroreductase activity|down regulation of coenzyme F420-dependent nitroimidazole catabolism|down-regulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|downregulation of coenzyme F420-dependent nitroimidazole catabolism|downregulation of coenzyme F420-dependent nitroimidazole reduction|down regulation of coenzyme F420-dependent nitroimidazole reduction|down-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|inhibition of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroreductase activity|down-regulation of coenzyme F420-dependent nitroimidazole catabolism|negative regulation of coenzyme F420-dependent nitroimidazole catabolism|negative regulation of coenzyme F420-dependent nitroimidazole breakdown|down-regulation of coenzyme F420-dependent nitroimidazole breakdown http://purl.obolibrary.org/obo/GO_1900289 UBERON:0036067 biolink:AnatomicalEntity superior endocardial cushion The endocardial cushion that forms on the dorsal surface of the AV canal. go-plus.json dorsal endocardial cushion http://purl.obolibrary.org/obo/UBERON_0036067 UBERON:0036069 biolink:AnatomicalEntity tracheoesophageal fold One of two longitudinal ridges that develop caudal to the pharynx and fuses to give rise to the tracheoesophageal septum. go-plus.json esophagotracheal fold http://purl.obolibrary.org/obo/UBERON_0036069 GO:1900286 biolink:BiologicalProcess negative regulation of cellotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport. go-plus.json down regulation of cellotriose transport|downregulation of cellotriose transport|down-regulation of cellotriose transport|inhibition of cellotriose transport http://purl.obolibrary.org/obo/GO_1900286 GO:1900285 biolink:BiologicalProcess regulation of cellotriose transport Any process that modulates the frequency, rate or extent of cellotriose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900285 GO:1900288 biolink:BiologicalProcess regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. go-plus.json regulation of coenzyme F420-dependent nitroreductase activity|regulation of coenzyme F420-dependent nitroimidazole breakdown|regulation of coenzyme F420-dependent nitroimidazole catabolism|regulation of coenzyme F420-dependent nitroimidazole reduction http://purl.obolibrary.org/obo/GO_1900288 GO:1900287 biolink:BiologicalProcess positive regulation of cellotriose transport Any process that activates or increases the frequency, rate or extent of cellotriose transport. go-plus.json upregulation of cellotriose transport|up regulation of cellotriose transport|activation of cellotriose transport|up-regulation of cellotriose transport http://purl.obolibrary.org/obo/GO_1900287 GO:1900293 biolink:BiologicalProcess positive regulation of galactotriose transport Any process that activates or increases the frequency, rate or extent of galactotriose transport. go-plus.json up-regulation of galactotriose transport|upregulation of galactotriose transport|up regulation of galactotriose transport|activation of galactotriose transport http://purl.obolibrary.org/obo/GO_1900293 GO:1900292 biolink:BiologicalProcess negative regulation of galactotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport. go-plus.json down-regulation of galactotriose transport|inhibition of galactotriose transport|down regulation of galactotriose transport|downregulation of galactotriose transport http://purl.obolibrary.org/obo/GO_1900292 GO:1900295 biolink:BiologicalProcess negative regulation of heptasaccharide transport Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport. go-plus.json down-regulation of heptasaccharide transport|inhibition of heptasaccharide transport|down regulation of heptasaccharide transport|downregulation of heptasaccharide transport http://purl.obolibrary.org/obo/GO_1900295 GO:1900294 biolink:BiologicalProcess regulation of heptasaccharide transport Any process that modulates the frequency, rate or extent of heptasaccharide transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900294 GO:1900291 biolink:BiologicalProcess regulation of galactotriose transport Any process that modulates the frequency, rate or extent of galactotriose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900291 GO:1900290 biolink:BiologicalProcess positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. go-plus.json up-regulation of coenzyme F420-dependent nitroreductase activity|up regulation of coenzyme F420-dependent nitroimidazole catabolism|activation of coenzyme F420-dependent nitroimidazole catabolism|up-regulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroimidazole breakdown|positive regulation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole reduction|upregulation of coenzyme F420-dependent nitroreductase activity|up-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|positive regulation of coenzyme F420-dependent nitroimidazole breakdown|up-regulation of coenzyme F420-dependent nitroimidazole catabolism|up regulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroimidazole reduction|up-regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|positive regulation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroreductase activity|positive regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|activation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process http://purl.obolibrary.org/obo/GO_1900290 GO:0071159 biolink:CellularComponent NF-kappaB complex A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. go-plus.json http://purl.obolibrary.org/obo/GO_0071159 GO:0071158 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071158 GO:0071157 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071157 GO:0071156 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071156 GO:0071155 biolink:CellularComponent G-protein alpha(13)-synembrin complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein. go-plus.json Ric-8A G alpha 13 subunit complex http://purl.obolibrary.org/obo/GO_0071155 GO:0071187 biolink:CellularComponent protocadherin-alpha-v4-protocadherin-gamma-b4 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdhga1-Pcdhgb4 complex http://purl.obolibrary.org/obo/GO_0071187 GO:0071186 biolink:CellularComponent protocadherin-alpha-v4-protocadherin-gamma-b2 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdhga1-Pcdhgb2 complex http://purl.obolibrary.org/obo/GO_0071186 UBERON:0036070 biolink:AnatomicalEntity tracheoesophageal septum The tracheoesophageal septum is formed from the tracheoesophageal folds which fuse in the midline to form a structure called tracheoesophageal septum. It divides the esophagus from the trachea. It divides the foregut tube into the laryngotracheal tube ventrally and esophagus dorsally. Developmental abnormalities can lead to a tracheoesophageal fistula. go-plus.json tracheoesophageal ridges|esophagotracheal septum http://purl.obolibrary.org/obo/UBERON_0036070 GO:0071185 biolink:CellularComponent protocadherin-alpha-v4-protocadherin-gamma-a3 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdhga1-Pcdhga3 complex http://purl.obolibrary.org/obo/GO_0071185 UBERON:0036073 biolink:AnatomicalEntity respiratory primordium mesenchyme go-plus.json respiratory primordium associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0036073 CHEBI:142590 biolink:ChemicalSubstance 3-aminoisobutanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142590 chebi_ph7_3 GO:0071184 biolink:CellularComponent protocadherin-alpha-v4-protocadherin-gamma-a1 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdhga1-Pcdha4 complex http://purl.obolibrary.org/obo/GO_0071184 UBERON:0036072 biolink:AnatomicalEntity respiratory primordium epithelium go-plus.json http://purl.obolibrary.org/obo/UBERON_0036072 GO:0071183 biolink:CellularComponent protocadherin-alpha-protocadherin-gamma complex A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0071183 GO:0071182 biolink:CellularComponent MAML3-RBP-Jkappa-ICN4 complex A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML3-RBP-Jkappa-Notch4 complex http://purl.obolibrary.org/obo/GO_0071182 GO:0071181 biolink:CellularComponent MAML3-RBP-Jkappa-ICN3 complex A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML3-RBP-Jkappa-Notch3 complex http://purl.obolibrary.org/obo/GO_0071181 GO:0071180 biolink:CellularComponent MAML3-RBP-Jkappa-ICN2 complex A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML3-RBP-Jkappa-Notch2 complex http://purl.obolibrary.org/obo/GO_0071180 GO:1900297 biolink:BiologicalProcess regulation of hexasaccharide transport Any process that modulates the frequency, rate or extent of hexasaccharide transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900297 GO:1900296 biolink:BiologicalProcess positive regulation of heptasaccharide transport Any process that activates or increases the frequency, rate or extent of heptasaccharide transport. go-plus.json up regulation of heptasaccharide transport|activation of heptasaccharide transport|up-regulation of heptasaccharide transport|upregulation of heptasaccharide transport http://purl.obolibrary.org/obo/GO_1900296 GO:1900299 biolink:BiologicalProcess positive regulation of hexasaccharide transport Any process that activates or increases the frequency, rate or extent of hexasaccharide transport. go-plus.json up-regulation of hexasaccharide transport|activation of hexasaccharide transport|up regulation of hexasaccharide transport|upregulation of hexasaccharide transport http://purl.obolibrary.org/obo/GO_1900299 CHEBI:142594 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142594 chebi_ph7_3 GO:1900298 biolink:BiologicalProcess negative regulation of hexasaccharide transport Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport. go-plus.json down-regulation of hexasaccharide transport|downregulation of hexasaccharide transport|down regulation of hexasaccharide transport|inhibition of hexasaccharide transport http://purl.obolibrary.org/obo/GO_1900298 GO:0071189 biolink:CellularComponent protocadherin-alpha-v7-protocadherin-gamma-a3 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdha7-Pcdhga3 complex http://purl.obolibrary.org/obo/GO_0071189 GO:0071188 biolink:CellularComponent protocadherin-alpha-v7-protocadherin-gamma-a1 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane. go-plus.json Pcdha7-Pcdhga1 complex http://purl.obolibrary.org/obo/GO_0071188 GO:0071176 biolink:CellularComponent MAML2-RBP-Jkappa-ICN2 complex A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML2-RBP-Jkappa-Notch2 complex http://purl.obolibrary.org/obo/GO_0071176 GO:0071175 biolink:CellularComponent MAML2-RBP-Jkappa-ICN1 complex A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML2-RBP-Jkappa-Notch1 complex http://purl.obolibrary.org/obo/GO_0071175 GO:0071174 biolink:BiologicalProcess mitotic spindle checkpoint signaling A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form. go-plus.json topoisomerase II checkpoint|signal transduction involved in mitotic spindle checkpoint|topo II checkpoint|mitotic cell cycle spindle checkpoint|mitotic spindle checkpoint|signal transduction involved in mitotic cell cycle spindle checkpoint http://purl.obolibrary.org/obo/GO_0071174 gocheck_do_not_manually_annotate GO:0071173 biolink:BiologicalProcess spindle assembly checkpoint signaling A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. go-plus.json SAC|spindle assembly checkpoint|signal transduction involved in spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_0071173 gocheck_do_not_manually_annotate GO:0071172 biolink:MolecularActivity dihydromonapterin reductase activity Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+. go-plus.json http://purl.obolibrary.org/obo/GO_0071172 GO:0071171 biolink:BiologicalProcess site-specific DNA replication termination at RTS1 barrier A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching. go-plus.json http://purl.obolibrary.org/obo/GO_0071171 GO:0071170 biolink:BiologicalProcess site-specific DNA replication termination A DNA replication termination process that takes place at a specific termination site. go-plus.json http://purl.obolibrary.org/obo/GO_0071170 CHEBI:142587 biolink:ChemicalSubstance N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_142587 chebi_ph7_3 CHEBI:142582 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142582 chebi_ph7_3 GO:0071179 biolink:CellularComponent MAML3-RBP-Jkappa-ICN1 complex A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML3-RBP-Jkappa-Notch1 complex http://purl.obolibrary.org/obo/GO_0071179 GO:0071178 biolink:CellularComponent MAML2-RBP-Jkappa-ICN4 complex A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML2-RBP-Jkappa-Notch4 complex http://purl.obolibrary.org/obo/GO_0071178 GO:0071177 biolink:CellularComponent MAML2-RBP-Jkappa-ICN3 complex A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. go-plus.json MAML2-RBP-Jkappa-Notch3 complex http://purl.obolibrary.org/obo/GO_0071177 SO:0001410 biolink:SequenceFeature experimental_feature A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer. go-plus.json analysis feature|experimental_output_artefact|experimental output artefact http://purl.obolibrary.org/obo/SO_0001410 SOFA CHEBI:35418 biolink:ChemicalSubstance N-acetylneuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35418 chebi_ph7_3 CHEBI:35417 biolink:ChemicalSubstance alpha-amino-acid residue radical go-plus.json http://purl.obolibrary.org/obo/CHEBI_35417 CHEBI:11449 biolink:ChemicalSubstance 2,5-didehydro-D-gluconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11449 chebi_ph7_3 CHEBI:35410 biolink:ChemicalSubstance primary diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35410 CHEBI:84387 biolink:ChemicalSubstance (1s,4s)-prephenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84387 GO:0061720 biolink:BiologicalProcess 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). go-plus.json http://purl.obolibrary.org/obo/GO_0061720 CHEBI:35412 biolink:ChemicalSubstance aminal go-plus.json http://purl.obolibrary.org/obo/CHEBI_35412 CHEBI:35411 biolink:ChemicalSubstance alkane-alpha,omega-diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35411 GO:0061722 biolink:BiologicalProcess sulphoglycolysis The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate. go-plus.json sulfoglycolysis http://purl.obolibrary.org/obo/GO_0061722 CHEBI:35414 biolink:ChemicalSubstance N-monoacetylalkane-alpha,omega-diamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35414 GO:0061721 biolink:BiologicalProcess 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-) The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-). MetaCyc:PWY-7446 go-plus.json http://purl.obolibrary.org/obo/GO_0061721 CHEBI:35416 biolink:ChemicalSubstance alpha-amino-acid residue anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35416 GO:0061724 biolink:BiologicalProcess lipophagy The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0061724 GO:0061723 biolink:BiologicalProcess glycophagy The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions. go-plus.json http://purl.obolibrary.org/obo/GO_0061723 CHEBI:35415 biolink:ChemicalSubstance alpha-amino-acid residue cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_35415 GO:0061726 biolink:BiologicalProcess mitochondrion disassembly The disaggregation of a mitochondrion into its constituent components. go-plus.json mitochondrion degradation http://purl.obolibrary.org/obo/GO_0061726 GO:0061725 biolink:BiologicalProcess cytosolic lipolysis The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases. go-plus.json http://purl.obolibrary.org/obo/GO_0061725 GO:0061728 biolink:BiologicalProcess GDP-mannose biosynthetic process from mannose The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose. go-plus.json http://purl.obolibrary.org/obo/GO_0061728 GO:0061727 biolink:BiologicalProcess methylglyoxal catabolic process to lactate The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate. go-plus.json http://purl.obolibrary.org/obo/GO_0061727 GO:0061729 biolink:BiologicalProcess GDP-mannose biosynthetic process from fructose-6-phosphate The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate. Reactome:R-HSA-446205 go-plus.json http://purl.obolibrary.org/obo/GO_0061729 CHEBI:35428 biolink:ChemicalSubstance ortho-fused bicyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_35428 CHEBI:11438 biolink:ChemicalSubstance 2,4-dichloro-cis,cis-muconate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_11438 chebi_ph7_3 CHEBI:84399 biolink:ChemicalSubstance 1,1',2-trilinoleoyl-2'-oleoyl cardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_84399 CHEBI:35421 biolink:ChemicalSubstance lithocholic acid sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35421 CHEBI:35420 biolink:ChemicalSubstance pregnenolone sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35420 CHEBI:84398 biolink:ChemicalSubstance tetralinoleoyl cardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_84398 CHEBI:35423 biolink:ChemicalSubstance L-arabinose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35423 GO:0061711 biolink:MolecularActivity N(6)-L-threonylcarbamoyladenine synthase activity Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA. RHEA:37059|Reactome:R-HSA-6784494|EC:2.3.1.234|MetaCyc:RXN-14570 go-plus.json http://purl.obolibrary.org/obo/GO_0061711 CHEBI:35425 biolink:ChemicalSubstance D-ribose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35425 GO:0061710 biolink:MolecularActivity L-threonylcarbamoyladenylate synthase Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O. RHEA:36407|EC:2.7.7.87|MetaCyc:RXN-14569 go-plus.json http://purl.obolibrary.org/obo/GO_0061710 GO:0061713 biolink:BiologicalProcess anterior neural tube closure The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline. go-plus.json http://purl.obolibrary.org/obo/GO_0061713 CHEBI:35427 biolink:ChemicalSubstance ortho-fused polycyclic hydrocarbon go-plus.json http://purl.obolibrary.org/obo/CHEBI_35427 GO:0061712 biolink:MolecularActivity tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine. EC:2.8.4.5|RHEA:37075|MetaCyc:RXN-14531 go-plus.json http://purl.obolibrary.org/obo/GO_0061712 CHEBI:35426 biolink:ChemicalSubstance ortho-fused bicyclic arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35426 GO:0061715 biolink:BiologicalProcess miRNA 2'-O-methylation The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0061715 GO:0061714 biolink:MolecularActivity folic acid receptor activity Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis. go-plus.json folate receptor activity http://purl.obolibrary.org/obo/GO_0061714 GO:0061717 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061717 GO:0061716 biolink:BiologicalProcess miRNA export from nucleus The directed movement of a processed miRNA from the nucleus to the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0061716 GO:0061719 biolink:BiologicalProcess glucose catabolic process to pyruvate utilizing ADP The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions. MetaCyc:P341-PWY go-plus.json http://purl.obolibrary.org/obo/GO_0061719 GO:0061718 biolink:BiologicalProcess glucose catabolic process to pyruvate The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate. go-plus.json glucose catabolism to pyruvate http://purl.obolibrary.org/obo/GO_0061718 GO:0046107 biolink:BiologicalProcess uracil biosynthetic process The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. go-plus.json uracil anabolism|uracil synthesis|uracil formation|uracil biosynthesis http://purl.obolibrary.org/obo/GO_0046107 GO:0046106 biolink:BiologicalProcess thymine biosynthetic process The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. go-plus.json thymine biosynthesis|thymine anabolism|thymine synthesis|thymine formation http://purl.obolibrary.org/obo/GO_0046106 GO:0046105 biolink:BiologicalProcess thymidine biosynthetic process The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. go-plus.json deoxyribosylthymine biosynthetic process|deoxyribosylthymine biosynthesis|thymidine anabolism|thymidine synthesis|thymidine biosynthesis|thymidine formation http://purl.obolibrary.org/obo/GO_0046105 GO:0046104 biolink:BiologicalProcess thymidine metabolic process The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. go-plus.json deoxyribosylthymine metabolism|thymidine metabolism|deoxyribosylthymine metabolic process http://purl.obolibrary.org/obo/GO_0046104 GO:0046103 biolink:BiologicalProcess inosine biosynthetic process The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. go-plus.json inosine biosynthesis|inosine anabolism|inosine synthesis|inosine formation http://purl.obolibrary.org/obo/GO_0046103 GO:0046102 biolink:BiologicalProcess inosine metabolic process The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. go-plus.json inosine metabolism http://purl.obolibrary.org/obo/GO_0046102 GO:0046101 biolink:BiologicalProcess hypoxanthine biosynthetic process The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate. go-plus.json hypoxanthine biosynthesis|hypoxanthine anabolism|hypoxanthine synthesis|hypoxanthine formation http://purl.obolibrary.org/obo/GO_0046101 GO:0046100 biolink:BiologicalProcess hypoxanthine metabolic process The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate. go-plus.json hypoxanthine metabolism http://purl.obolibrary.org/obo/GO_0046100 GO:0061740 biolink:BiologicalProcess protein targeting to lysosome involved in chaperone-mediated autophagy The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0061740 GO:0061742 biolink:CellularComponent chaperone-mediated autophagy translocation complex A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy. go-plus.json chaperone-mediated autophagy receptor complex|CMA translocation complex|CMA receptor complex http://purl.obolibrary.org/obo/GO_0061742 GO:0061741 biolink:BiologicalProcess obsolete chaperone-mediated protein transport involved in chaperone-mediated autophagy OBSOLETE. The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy. go-plus.json http://purl.obolibrary.org/obo/GO_0061741 GO:0061744 biolink:BiologicalProcess motor behavior The specific neuromuscular movement of a single organism in response to external or internal stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0061744 GO:0061743 biolink:BiologicalProcess motor learning Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience. go-plus.json http://purl.obolibrary.org/obo/GO_0061743 GO:0061746 biolink:MolecularActivity obsolete single-stranded DNA-dependent GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0061746 GO:0046109 biolink:BiologicalProcess uridine biosynthetic process The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. go-plus.json uridine biosynthesis|uridine anabolism|uridine synthesis|uridine formation http://purl.obolibrary.org/obo/GO_0046109 GO:0061745 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061745 GO:0046108 biolink:BiologicalProcess uridine metabolic process The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. go-plus.json uridine metabolism http://purl.obolibrary.org/obo/GO_0046108 GO:0061748 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061748 GO:0061747 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061747 GO:0061749 biolink:MolecularActivity forked DNA-dependent helicase activity Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0061749 GO:0046110 biolink:BiologicalProcess xanthine metabolic process The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids. go-plus.json xanthine metabolism http://purl.obolibrary.org/obo/GO_0046110 GO:0046118 biolink:BiologicalProcess 7-methylguanosine biosynthetic process The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA. go-plus.json 7-methylguanosine anabolism|7-methylguanosine synthesis|7-methylguanosine biosynthesis|7-methylguanosine formation http://purl.obolibrary.org/obo/GO_0046118 GO:0046117 biolink:BiologicalProcess queuosine catabolic process The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. go-plus.json queuosine degradation|queuosine breakdown|queuosine catabolism http://purl.obolibrary.org/obo/GO_0046117 CHEBI:35406 biolink:ChemicalSubstance oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35406 GO:0046116 biolink:BiologicalProcess queuosine metabolic process The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. go-plus.json queuosine metabolism http://purl.obolibrary.org/obo/GO_0046116 GO:0046115 biolink:BiologicalProcess guanosine catabolic process The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution. go-plus.json guanosine phosphorolysis|guanosine catabolism|guanosine degradation|guanosine breakdown http://purl.obolibrary.org/obo/GO_0046115 GO:0046114 biolink:BiologicalProcess guanosine biosynthetic process The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution. go-plus.json guanosine synthesis|guanosine formation|guanosine biosynthesis|guanosine anabolism http://purl.obolibrary.org/obo/GO_0046114 GO:0046113 biolink:BiologicalProcess nucleobase catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. go-plus.json nucleobase degradation|nucleobase breakdown|nucleobase catabolism http://purl.obolibrary.org/obo/GO_0046113 GO:0046112 biolink:BiologicalProcess nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. go-plus.json nucleobase anabolism|nucleobase biosynthesis|nucleobase synthesis|nucleobase formation http://purl.obolibrary.org/obo/GO_0046112 GO:0046111 biolink:BiologicalProcess xanthine biosynthetic process The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids. go-plus.json xanthine biosynthesis|xanthine anabolism|xanthine synthesis|xanthine formation http://purl.obolibrary.org/obo/GO_0046111 GO:0061731 biolink:MolecularActivity ribonucleoside-diphosphate reductase activity Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor. go-plus.json ribonucleoside 5'-diphosphate reductase activity|ribonucleotide diphosphate reductase activity|purine/pyrimidine nucleoside diphosphate reduction|nucleoside diphosphate reductase activity|class II ribonucleotide reductase activity|class I ribonucleotide reductase activity|class III ribonucleotide reductase activity|adenosylcobalamin-dependent ribonucleotide reductase activity|aerobic non-heme iron-dependent ribonucleotide reductase activity|anaerobic iron-sulfur-dependent ribonucleotide reductase activity|class II ribonucleoside-diphosphate reductase activity|ribonucleotide reductase activity|RNR http://purl.obolibrary.org/obo/GO_0061731 CHEBI:35401 biolink:ChemicalSubstance chromium oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35401 UBERON:0002691 biolink:AnatomicalEntity ventral tegmental area Unpaired midbrain region situated in the ventromedial portion of the reticular formation. The VTA is medial to the substantia nigra and ventral to the red nucleus, and extends caudally from the posterior hypothalamus in the diencephalon. The VTA contains dopamine neurons that project to various limbic and cortical areas and is a critical component of the brain's reward circuitry. go-plus.json ventromedial mesencephalic tegmentum|area tegmentalis ventralis|a10a|ventral tegmental nucleus (tsai)|VTA|ventral tegmental area of tsai|ventral tegmental area (Tsai)|area tegmentalis ventralis (Tsai)|tegmentum ventrale|ventral tegmental nucleus of tsai|ventral tegmental nucleus (Rioch)|ventral brain stem http://purl.obolibrary.org/obo/UBERON_0002691 GO:0061730 biolink:MolecularActivity C-rich strand telomeric DNA binding Binding to C-rich, single-stranded, telomere-associated DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0061730 CHEBI:35400 biolink:ChemicalSubstance meso-tartrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35400 GO:0061733 biolink:MolecularActivity peptide-lysine-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide. Reactome:R-HSA-6811508|Reactome:R-HSA-9626945|Reactome:R-HSA-8951966|Reactome:R-HSA-9617758|Reactome:R-HSA-9620515 go-plus.json http://purl.obolibrary.org/obo/GO_0061733 PR:000011459 biolink:Protein neurotrophin-3 A neurotrophin that is a translation product of the human NTF3 gene or a 1:1 ortholog thereof. go-plus.json NT-3|neurotrophic factor|nerve growth factor 2|Ntf-3|HDNF|NTF3|NGF-2 http://purl.obolibrary.org/obo/PR_000011459 CHEBI:35403 biolink:ChemicalSubstance chromium coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_35403 GO:0061732 biolink:BiologicalProcess mitochondrial acetyl-CoA biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA. Reactome:R-HSA-372342.1|Reactome:R-HSA-71397.1 go-plus.json http://purl.obolibrary.org/obo/GO_0061732 CHEBI:35402 biolink:ChemicalSubstance chromium oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35402 GO:0061735 biolink:BiologicalProcess DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule. go-plus.json dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0061735 CHEBI:35405 biolink:ChemicalSubstance transition element oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35405 GO:0061734 biolink:BiologicalProcess parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule. go-plus.json Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization http://purl.obolibrary.org/obo/GO_0061734 GO:0046119 biolink:BiologicalProcess 7-methylguanosine catabolic process The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA. go-plus.json 7-methylguanosine degradation|7-methylguanosine breakdown|7-methylguanosine catabolism http://purl.obolibrary.org/obo/GO_0046119 CHEBI:35404 biolink:ChemicalSubstance chromate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35404 chebi_ph7_3 GO:0061737 biolink:BiologicalProcess leukotriene signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0061737 GO:0061736 biolink:BiologicalProcess engulfment of target by autophagosome The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. go-plus.json http://purl.obolibrary.org/obo/GO_0061736 GO:0061739 biolink:BiologicalProcess protein lipidation involved in autophagosome assembly The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0061739 GO:0061738 biolink:BiologicalProcess late endosomal microautophagy The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment. go-plus.json http://purl.obolibrary.org/obo/GO_0061738 SO:0001412 biolink:SequenceFeature topologically_defined_region A DNA region within which self-interaction occurs more often than expected by chance because of DNA-looping. go-plus.json topologically defined region http://purl.obolibrary.org/obo/SO_0001412 SOFA NCBITaxon:71421 biolink:OrganismalEntity Haemophilus influenzae Rd KW20 go-plus.json Haemophilus influenzae KW20|Haemophilus influenzae Rd http://purl.obolibrary.org/obo/NCBITaxon_71421 SO:0001411 biolink:SequenceFeature biological_region A region defined by its disposition to be involved in a biological process. go-plus.json INSDC_misc_feature|INSDC_note:biological_region|biological region http://purl.obolibrary.org/obo/SO_0001411 SOFA GO:0046121 biolink:BiologicalProcess deoxyribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json deoxyribonucleoside catabolism|deoxyribonucleoside degradation|deoxyribonucleoside breakdown http://purl.obolibrary.org/obo/GO_0046121 UBERON:0012082 biolink:AnatomicalEntity bronchial lumen An anatomical cavity that is part of a bronchus. go-plus.json bronchial lumen|lumen of bronchus http://purl.obolibrary.org/obo/UBERON_0012082 UBERON:0012081 biolink:AnatomicalEntity patella pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a patella. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012081 GO:0046120 biolink:BiologicalProcess deoxyribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json deoxyribonucleoside anabolism|deoxyribonucleoside synthesis|deoxyribonucleoside formation|deoxyribonucleoside biosynthesis http://purl.obolibrary.org/obo/GO_0046120 UBERON:0012080 biolink:AnatomicalEntity patella cartilage element A cartilaginous condensation that has the potential to develop into a patella. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012080 UBERON:0012085 biolink:AnatomicalEntity lumen of tertiary bronchus An anatomical cavity that is part of a segmental bronchus. go-plus.json segmental bronchial lumen|lumen of segmental bronchus http://purl.obolibrary.org/obo/UBERON_0012085 UBERON:0012084 biolink:AnatomicalEntity lumen of secondary bronchus An anatomical cavity that is part of a lobar bronchus. go-plus.json lobar bronchial lumen|lumen of lobar bronchus|secondary bronchial lumen http://purl.obolibrary.org/obo/UBERON_0012084 GO:0046129 biolink:BiologicalProcess purine ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json purine ribonucleoside anabolism|purine ribonucleoside synthesis|purine ribonucleoside formation|purine ribonucleoside biosynthesis http://purl.obolibrary.org/obo/GO_0046129 GO:0046128 biolink:BiologicalProcess purine ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json purine ribonucleoside metabolism http://purl.obolibrary.org/obo/GO_0046128 GO:0046127 biolink:BiologicalProcess pyrimidine deoxyribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json pyrimidine deoxyribonucleoside degradation|pyrimidine deoxyribonucleoside breakdown|pyrimidine deoxyribonucleoside catabolism http://purl.obolibrary.org/obo/GO_0046127 GO:0046126 biolink:BiologicalProcess pyrimidine deoxyribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json pyrimidine deoxyribonucleoside anabolism|pyrimidine deoxyribonucleoside synthesis|pyrimidine deoxyribonucleoside biosynthesis|pyrimidine deoxyribonucleoside formation http://purl.obolibrary.org/obo/GO_0046126 GO:0046125 biolink:BiologicalProcess pyrimidine deoxyribonucleoside metabolic process The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json pyrimidine deoxyribonucleoside metabolism http://purl.obolibrary.org/obo/GO_0046125 GO:0046124 biolink:BiologicalProcess purine deoxyribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json purine deoxyribonucleoside degradation|purine deoxyribonucleoside breakdown|purine deoxyribonucleoside catabolism http://purl.obolibrary.org/obo/GO_0046124 GO:0061760 biolink:BiologicalProcess antifungal innate immune response An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. go-plus.json http://purl.obolibrary.org/obo/GO_0061760 GO:0046123 biolink:BiologicalProcess purine deoxyribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json purine deoxyribonucleoside biosynthesis|purine deoxyribonucleoside anabolism|purine deoxyribonucleoside synthesis|purine deoxyribonucleoside formation http://purl.obolibrary.org/obo/GO_0046123 CHEBI:11408 biolink:ChemicalSubstance 2,3,4,5-tetrahydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_11408 chebi_ph7_3 GO:0046122 biolink:BiologicalProcess purine deoxyribonucleoside metabolic process The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). go-plus.json purine deoxyribonucleoside metabolism http://purl.obolibrary.org/obo/GO_0046122 GO:0061762 biolink:BiologicalProcess CAMKK-AMPK signaling cascade A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity. go-plus.json stress-activated AMP-activated protein kinase signaling cascade http://purl.obolibrary.org/obo/GO_0061762 GO:0061761 biolink:MolecularActivity alpha-latrotoxin receptor binding Binding to an alpha-latrotoxin receptor. go-plus.json latrophilin binding|lasso receptor binding http://purl.obolibrary.org/obo/GO_0061761 GO:0061764 biolink:BiologicalProcess late endosome to lysosome transport via multivesicular body sorting pathway The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061764 GO:0061763 biolink:BiologicalProcess multivesicular body-lysosome fusion The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle. go-plus.json MVB-lysosome fusion|fusion of MVB to lysosome|fusion of multivesicular body to lysosome http://purl.obolibrary.org/obo/GO_0061763 GO:0061766 biolink:BiologicalProcess positive regulation of lung blood pressure The process that increases the force with which blood travels through the lungs. go-plus.json positive regulation of pulmonary blood pressure http://purl.obolibrary.org/obo/GO_0061766 GO:0061765 biolink:BiologicalProcess modulation by virus of host NIK/NF-kappaB signaling Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host. go-plus.json http://purl.obolibrary.org/obo/GO_0061765 GO:0061768 biolink:MolecularActivity magnesium:sodium antiporter activity Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0061768 GO:0061767 biolink:BiologicalProcess negative regulation of lung blood pressure The process that decreases the force with which blood travels through the lungs. go-plus.json negative regulation of pulmonary blood pressure http://purl.obolibrary.org/obo/GO_0061767 GO:0061769 biolink:MolecularActivity ribosylnicotinate kinase activity Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H(+) + nicotinate mononucleotide. Reactome:R-HSA-8869607|Reactome:R-HSA-8869606 go-plus.json http://purl.obolibrary.org/obo/GO_0061769 GO:0046132 biolink:BiologicalProcess pyrimidine ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json pyrimidine ribonucleoside biosynthesis|pyrimidine ribonucleoside formation|pyrimidine ribonucleoside anabolism|pyrimidine ribonucleoside synthesis http://purl.obolibrary.org/obo/GO_0046132 UBERON:0012071 biolink:AnatomicalEntity palate bone Any bone that is part of a palate. go-plus.json palatal bone http://purl.obolibrary.org/obo/UBERON_0012071 GO:1900209 biolink:BiologicalProcess negative regulation of cardiolipin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process. go-plus.json down regulation of cardiolipin metabolic process|down-regulation of diphosphatidylglycerol metabolism|negative regulation of diphosphatidylglycerol metabolism|inhibition of cardiolipin metabolism|downregulation of cardiolipin metabolic process|down-regulation of diphosphatidylglycerol metabolic process|negative regulation of diphosphatidylglycerol metabolic process|down-regulation of cardiolipin metabolic process|inhibition of diphosphatidylglycerol metabolism|downregulation of diphosphatidylglycerol metabolic process|down-regulation of cardiolipin metabolism|negative regulation of cardiolipin metabolism|down regulation of diphosphatidylglycerol metabolic process|inhibition of cardiolipin metabolic process|down regulation of diphosphatidylglycerol metabolism|downregulation of diphosphatidylglycerol metabolism|downregulation of cardiolipin metabolism|inhibition of diphosphatidylglycerol metabolic process|down regulation of cardiolipin metabolism http://purl.obolibrary.org/obo/GO_1900209 GO:0046131 biolink:BiologicalProcess pyrimidine ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json pyrimidine ribonucleoside metabolism http://purl.obolibrary.org/obo/GO_0046131 UBERON:0012070 biolink:AnatomicalEntity palatal tooth A tooth that is on the roof of the mouth. go-plus.json palatal teeth http://purl.obolibrary.org/obo/UBERON_0012070 GO:0046130 biolink:BiologicalProcess purine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json purine ribonucleoside catabolism|purine ribonucleoside degradation|purine ribonucleoside breakdown http://purl.obolibrary.org/obo/GO_0046130 GO:1900206 biolink:BiologicalProcess regulation of pronephric nephron tubule development Any process that modulates the frequency, rate or extent of pronephric nephron tubule development. go-plus.json http://purl.obolibrary.org/obo/GO_1900206 UBERON:0012075 biolink:AnatomicalEntity replacement bone Bone that forms as a replacement of another structural tissue. go-plus.json replacement bones http://purl.obolibrary.org/obo/UBERON_0012075 GO:1900205 biolink:BiologicalProcess apoptotic process involved in metanephric nephron tubule development Any apoptotic process that is involved in metanephric nephron tubule development. go-plus.json programmed cell death by apoptosis of metanephric nephron tubule development|apoptosis of metanephric nephron tubule development|signaling (initiator) caspase activity of metanephric nephron tubule development|type I programmed cell death of metanephric nephron tubule development|apoptotic cell death of metanephric nephron tubule development|apoptotic process of metanephric nephron tubule development|apoptotic programmed cell death of metanephric nephron tubule development|apoptotic program of metanephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900205 UBERON:0012074 biolink:AnatomicalEntity bony part of hard palate A subdivision of skeletal system that subdivision_of a hard palate. go-plus.json palatum osseum|hard palate skeleton|bony palate http://purl.obolibrary.org/obo/UBERON_0012074 GO:1900208 biolink:BiologicalProcess regulation of cardiolipin metabolic process Any process that modulates the frequency, rate or extent of cardiolipin metabolic process. go-plus.json regulation of diphosphatidylglycerol metabolic process|regulation of diphosphatidylglycerol metabolism|regulation of cardiolipin metabolism http://purl.obolibrary.org/obo/GO_1900208 UBERON:0012073 biolink:AnatomicalEntity tooth of palatine bone A tooth that is attached to a palatine bone. go-plus.json palatine tooth|palatine teeth http://purl.obolibrary.org/obo/UBERON_0012073 GO:1900207 biolink:BiologicalProcess negative regulation of pronephric nephron tubule development Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development. go-plus.json inhibition of pronephric nephron tubule development|down regulation of pronephric nephron tubule development|downregulation of pronephric nephron tubule development|down-regulation of pronephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900207 UBERON:0012072 biolink:AnatomicalEntity palatal part of dermatocranium go-plus.json palatal series|dermatocranium, palatal series http://purl.obolibrary.org/obo/UBERON_0012072 GO:1900202 biolink:BiologicalProcess obsolete negative regulation of spread of virus in host, cell to cell OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of spread of virus in host, cell to cell. go-plus.json inhibition of cell to cell spread of virus within host|inhibition of spread of virus within host, cell to cell|down regulation of spread of virus in host, cell to cell|inhibition of viral spread within host, cell to cell|downregulation of spread of virus in host, cell to cell|down regulation of spread of virus within host, cell to cell|downregulation of spread of virus within host, cell to cell|down-regulation of cell to cell spread of virus within host|negative regulation of cell to cell spread of virus within host|down-regulation of spread of virus in host, cell to cell|negative regulation of viral spread within host, cell to cell|down-regulation of viral spread within host, cell to cell|inhibition of spread of virus in host, cell to cell|down-regulation of spread of virus within host, cell to cell|negative regulation of spread of virus within host, cell to cell|downregulation of cell to cell spread of virus within host|down regulation of cell to cell spread of virus within host|downregulation of viral spread within host, cell to cell|down regulation of viral spread within host, cell to cell|negative regulation of spread of virus in host, cell to cell http://purl.obolibrary.org/obo/GO_1900202 GO:0046139 biolink:BiologicalProcess obsolete coenzyme and prosthetic group catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes and prosthetic groups. go-plus.json coenzyme and prosthetic group catabolism|coenzyme and prosthetic group degradation|coenzyme and prosthetic group breakdown|coenzyme and prosthetic group catabolic process http://purl.obolibrary.org/obo/GO_0046139 GO:1900201 biolink:BiologicalProcess obsolete regulation of spread of virus in host, cell to cell OBSOLETE. Any process that modulates the frequency, rate or extent of spread of virus in host, cell to cell. go-plus.json regulation of spread of virus within host, cell to cell|regulation of spread of virus in host, cell to cell|regulation of cell to cell spread of virus within host|regulation of viral spread within host, cell to cell http://purl.obolibrary.org/obo/GO_1900201 GO:0046138 biolink:BiologicalProcess obsolete coenzyme and prosthetic group biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes and prosthetic groups. go-plus.json coenzyme and prosthetic group synthesis|coenzyme and prosthetic group formation|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group biosynthesis|coenzyme and prosthetic group anabolism http://purl.obolibrary.org/obo/GO_0046138 GO:1900204 biolink:BiologicalProcess apoptotic process involved in metanephric collecting duct development Any apoptotic process that is involved in metanephric collecting duct development. go-plus.json type I programmed cell death of metanephric collecting duct development|apoptosis of metanephric collecting duct development|apoptotic programmed cell death of metanephric collecting duct development|apoptotic process of metanephric collecting duct development|apoptotic cell death of metanephric collecting duct development|programmed cell death by apoptosis of metanephric collecting duct development|signaling (initiator) caspase activity of metanephric collecting duct development|apoptotic program of metanephric collecting duct development http://purl.obolibrary.org/obo/GO_1900204 GO:0046137 biolink:BiologicalProcess negative regulation of vitamin metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json inhibition of vitamin metabolic process|down regulation of vitamin metabolic process|downregulation of vitamin metabolic process|down-regulation of vitamin metabolic process|negative regulation of vitamin metabolism http://purl.obolibrary.org/obo/GO_0046137 GO:1900203 biolink:BiologicalProcess obsolete positive regulation of spread of virus in host, cell to cell OBSOLETE. Any process that activates or increases the frequency, rate or extent of spread of virus in host, cell to cell. go-plus.json upregulation of viral spread within host, cell to cell|upregulation of spread of virus within host, cell to cell|up-regulation of cell to cell spread of virus within host|up regulation of spread of virus in host, cell to cell|up-regulation of viral spread within host, cell to cell|activation of spread of virus in host, cell to cell|activation of cell to cell spread of virus within host|up regulation of spread of virus within host, cell to cell|activation of viral spread within host, cell to cell|positive regulation of cell to cell spread of virus within host|positive regulation of spread of virus within host, cell to cell|up regulation of cell to cell spread of virus within host|positive regulation of viral spread within host, cell to cell|up-regulation of spread of virus in host, cell to cell|activation of spread of virus within host, cell to cell|up regulation of viral spread within host, cell to cell|up-regulation of spread of virus within host, cell to cell|positive regulation of spread of virus in host, cell to cell|upregulation of cell to cell spread of virus within host|upregulation of spread of virus in host, cell to cell http://purl.obolibrary.org/obo/GO_1900203 GO:0046136 biolink:BiologicalProcess positive regulation of vitamin metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. go-plus.json positive regulation of vitamin metabolism|up-regulation of vitamin metabolic process|upregulation of vitamin metabolic process|up regulation of vitamin metabolic process|activation of vitamin metabolic process|stimulation of vitamin metabolic process http://purl.obolibrary.org/obo/GO_0046136 GO:0046135 biolink:BiologicalProcess pyrimidine nucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json pyrimidine nucleoside degradation|pyrimidine nucleoside breakdown|pyrimidine nucleoside catabolism http://purl.obolibrary.org/obo/GO_0046135 GO:0046134 biolink:BiologicalProcess pyrimidine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). go-plus.json pyrimidine nucleoside anabolism|pyrimidine nucleoside synthesis|pyrimidine nucleoside formation|pyrimidine nucleoside biosynthesis http://purl.obolibrary.org/obo/GO_0046134 GO:1900200 biolink:BiologicalProcess mesenchymal cell apoptotic process involved in metanephros development Any mesenchymal cell apoptotic process that is involved in metanephros development. go-plus.json mesenchymal cell apoptosis involved in metanephros development http://purl.obolibrary.org/obo/GO_1900200 GO:0046133 biolink:BiologicalProcess pyrimidine ribonucleoside catabolic process The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. go-plus.json pyrimidine ribonucleoside degradation|pyrimidine ribonucleoside breakdown|pyrimidine ribonucleoside catabolism http://purl.obolibrary.org/obo/GO_0046133 GO:0061751 biolink:MolecularActivity neutral sphingomyelin phosphodiesterase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment. go-plus.json neutral SMase|neutral sphingomyelinase http://purl.obolibrary.org/obo/GO_0061751 GO:0061750 biolink:MolecularActivity acid sphingomyelin phosphodiesterase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment. go-plus.json acid SMase|acid sphingomyelinase http://purl.obolibrary.org/obo/GO_0061750 GO:0061753 biolink:BiologicalProcess substrate localization to autophagosome The localization process by which an autophagic substrate is delivered to a forming autophagosome. go-plus.json substrate sequestration to autophagosome|substrate sequestration to phagophore http://purl.obolibrary.org/obo/GO_0061753 GO:0061752 biolink:MolecularActivity telomeric repeat-containing RNA binding Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats. go-plus.json TERRA binding http://purl.obolibrary.org/obo/GO_0061752 GO:0061755 biolink:BiologicalProcess positive regulation of circulating fibrinogen levels Any process that increases the quantity of fibrinogen circulating in the bloodstream. go-plus.json http://purl.obolibrary.org/obo/GO_0061755 GO:0061754 biolink:BiologicalProcess negative regulation of circulating fibrinogen levels Any process that reduces the quantity of fibrinogen circulating in the bloodstream. go-plus.json http://purl.obolibrary.org/obo/GO_0061754 GO:0061757 biolink:BiologicalProcess leukocyte adhesion to arterial endothelial cell The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0061757 GO:0061756 biolink:BiologicalProcess leukocyte adhesion to vascular endothelial cell The attachment of a leukocyte to vascular endothelial cell via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0061756 GO:0061759 biolink:MolecularActivity alpha-ketoglutarate reductase activity Catalysis of the reaction: 2-oxoglutarate + reduced acceptor = (S)-2-hydroxyglutarate + acceptor. RHEA:21254 go-plus.json 2-oxoglutarate reductase activity|2-hydroxyglutarate dehydrogenase activity, reverse reaction|D-2HG reductase activity|2-ketoglutarate reductase activity http://purl.obolibrary.org/obo/GO_0061759 GO:0061758 biolink:MolecularActivity 2-hydroxyglutarate dehydrogenase activity, forward reaction Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor. RHEA:21253 go-plus.json alpha-ketoglutarate reductase activity, reverse reaction http://purl.obolibrary.org/obo/GO_0061758 GO:0046143 biolink:BiologicalProcess obsolete positive regulation of coenzyme and prosthetic group metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups. go-plus.json positive regulation of coenzyme and prosthetic group metabolic process http://purl.obolibrary.org/obo/GO_0046143 GO:0046142 biolink:BiologicalProcess obsolete negative regulation of coenzyme and prosthetic group metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups. go-plus.json negative regulation of coenzyme and prosthetic group metabolic process http://purl.obolibrary.org/obo/GO_0046142 GO:0046141 biolink:BiologicalProcess corrin catabolic process The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule. go-plus.json corrin degradation|corrin breakdown|corrin catabolism http://purl.obolibrary.org/obo/GO_0046141 GO:0046140 biolink:BiologicalProcess corrin biosynthetic process The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule. go-plus.json corrin biosynthesis|corrin anabolism|corrin synthesis|corrin formation http://purl.obolibrary.org/obo/GO_0046140 GO:1900217 biolink:BiologicalProcess regulation of apoptotic process involved in metanephric nephron tubule development Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. go-plus.json regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|regulation of type I programmed cell death of metanephric nephron tubule development|regulation of apoptotic cell death of metanephric nephron tubule development|regulation of apoptosis of metanephric nephron tubule development|regulation of apoptotic process of metanephric nephron tubule development|regulation of apoptotic programmed cell death of metanephric nephron tubule development|regulation of apoptotic program of metanephric nephron tubule development|regulation of programmed cell death by apoptosis of metanephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900217 GO:1900216 biolink:BiologicalProcess positive regulation of apoptotic process involved in metanephric collecting duct development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. go-plus.json up regulation of programmed cell death by apoptosis of metanephric collecting duct development|upregulation of apoptotic program of metanephric collecting duct development|activation of apoptotic process of metanephric collecting duct development|up regulation of apoptosis of metanephric collecting duct development|upregulation of apoptotic process involved in metanephric collecting duct development|positive regulation of programmed cell death by apoptosis of metanephric collecting duct development|positive regulation of apoptotic programmed cell death of metanephric collecting duct development|positive regulation of apoptotic process of metanephric collecting duct development|up-regulation of apoptotic cell death of metanephric collecting duct development|up regulation of signaling (initiator) caspase activity of metanephric collecting duct development|up regulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of type I programmed cell death of metanephric collecting duct development|up regulation of apoptotic process of metanephric collecting duct development|positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development|activation of programmed cell death by apoptosis of metanephric collecting duct development|up-regulation of apoptotic program of metanephric collecting duct development|upregulation of apoptosis of metanephric collecting duct development|up regulation of apoptotic process involved in metanephric collecting duct development|activation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of programmed cell death by apoptosis of metanephric collecting duct development|activation of apoptotic process involved in metanephric collecting duct development|upregulation of apoptotic cell death of metanephric collecting duct development|activation of apoptotic program of metanephric collecting duct development|up regulation of type I programmed cell death of metanephric collecting duct development|upregulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of apoptotic process of metanephric collecting duct development|up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|positive regulation of type I programmed cell death of metanephric collecting duct development|up-regulation of apoptosis of metanephric collecting duct development|positive regulation of apoptotic program of metanephric collecting duct development|up regulation of apoptotic program of metanephric collecting duct development|upregulation of programmed cell death by apoptosis of metanephric collecting duct development|activation of type I programmed cell death of metanephric collecting duct development|up regulation of apoptotic cell death of metanephric collecting duct development|up-regulation of apoptotic process involved in metanephric collecting duct development|up-regulation of apoptotic programmed cell death of metanephric collecting duct development|up-regulation of apoptotic process of metanephric collecting duct development|positive regulation of apoptotic cell death of metanephric collecting duct development|activation of apoptosis of metanephric collecting duct development|upregulation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of type I programmed cell death of metanephric collecting duct development|activation of apoptotic programmed cell death of metanephric collecting duct development|activation of apoptotic cell death of metanephric collecting duct development|positive regulation of apoptosis of metanephric collecting duct development http://purl.obolibrary.org/obo/GO_1900216 GO:1900219 biolink:BiologicalProcess positive regulation of apoptotic process involved in metanephric nephron tubule development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. go-plus.json up regulation of apoptotic cell death of metanephric nephron tubule development|activation of apoptotic process involved in metanephric nephron tubule development|upregulation of programmed cell death by apoptosis of metanephric nephron tubule development|upregulation of apoptosis of metanephric nephron tubule development|up-regulation of apoptotic program of metanephric nephron tubule development|upregulation of type I programmed cell death of metanephric nephron tubule development|upregulation of apoptotic process of metanephric nephron tubule development|upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development|upregulation of apoptotic programmed cell death of metanephric nephron tubule development|upregulation of apoptotic cell death of metanephric nephron tubule development|up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|up regulation of apoptotic process involved in metanephric nephron tubule development|up regulation of apoptosis of metanephric nephron tubule development|upregulation of apoptotic program of metanephric nephron tubule development|positive regulation of apoptosis of metanephric nephron tubule development|up-regulation of type I programmed cell death of metanephric nephron tubule development|up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of apoptotic process of metanephric nephron tubule development|activation of programmed cell death by apoptosis of metanephric nephron tubule development|up regulation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of apoptotic process of metanephric nephron tubule development|up-regulation of apoptotic cell death of metanephric nephron tubule development|activation of apoptosis of metanephric nephron tubule development|positive regulation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development|activation of signaling (initiator) caspase activity of metanephric nephron tubule development|upregulation of apoptotic process involved in metanephric nephron tubule development|activation of type I programmed cell death of metanephric nephron tubule development|up regulation of apoptotic program of metanephric nephron tubule development|activation of apoptotic process of metanephric nephron tubule development|up regulation of programmed cell death by apoptosis of metanephric nephron tubule development|up-regulation of apoptosis of metanephric nephron tubule development|positive regulation of apoptotic program of metanephric nephron tubule development|activation of apoptotic cell death of metanephric nephron tubule development|activation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of type I programmed cell death of metanephric nephron tubule development|positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of type I programmed cell death of metanephric nephron tubule development|up-regulation of apoptotic process of metanephric nephron tubule development|activation of apoptotic program of metanephric nephron tubule development|positive regulation of apoptotic cell death of metanephric nephron tubule development|up-regulation of apoptotic programmed cell death of metanephric nephron tubule development|up-regulation of apoptotic process involved in metanephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900219 GO:1900218 biolink:BiologicalProcess negative regulation of apoptotic process involved in metanephric nephron tubule development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. go-plus.json downregulation of apoptotic cell death of metanephric nephron tubule development|down regulation of type I programmed cell death of metanephric nephron tubule development|down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|inhibition of apoptotic process of metanephric nephron tubule development|inhibition of apoptotic programmed cell death of metanephric nephron tubule development|down regulation of apoptosis of metanephric nephron tubule development|inhibition of programmed cell death by apoptosis of metanephric nephron tubule development|down-regulation of apoptotic process involved in metanephric nephron tubule development|down regulation of apoptotic cell death of metanephric nephron tubule development|downregulation of apoptosis of metanephric nephron tubule development|inhibition of apoptotic program of metanephric nephron tubule development|inhibition of type I programmed cell death of metanephric nephron tubule development|inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development|down regulation of apoptotic process of metanephric nephron tubule development|down regulation of apoptotic programmed cell death of metanephric nephron tubule development|inhibition of apoptotic cell death of metanephric nephron tubule development|downregulation of apoptotic process of metanephric nephron tubule development|down regulation of apoptotic program of metanephric nephron tubule development|downregulation of apoptotic process involved in metanephric nephron tubule development|downregulation of apoptotic programmed cell death of metanephric nephron tubule development|negative regulation of apoptosis of metanephric nephron tubule development|down-regulation of apoptosis of metanephric nephron tubule development|down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development|down regulation of apoptotic process involved in metanephric nephron tubule development|downregulation of apoptotic program of metanephric nephron tubule development|inhibition of apoptotic process involved in metanephric nephron tubule development|down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|negative regulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of apoptotic process of metanephric nephron tubule development|negative regulation of apoptotic process of metanephric nephron tubule development|negative regulation of apoptotic programmed cell death of metanephric nephron tubule development|down-regulation of apoptotic programmed cell death of metanephric nephron tubule development|negative regulation of apoptotic cell death of metanephric nephron tubule development|down-regulation of apoptotic cell death of metanephric nephron tubule development|downregulation of programmed cell death by apoptosis of metanephric nephron tubule development|down-regulation of apoptotic program of metanephric nephron tubule development|negative regulation of apoptotic program of metanephric nephron tubule development|inhibition of apoptosis of metanephric nephron tubule development|downregulation of type I programmed cell death of metanephric nephron tubule development|down regulation of programmed cell death by apoptosis of metanephric nephron tubule development|downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development http://purl.obolibrary.org/obo/GO_1900218 GO:1900213 biolink:BiologicalProcess positive regulation of mesenchymal cell apoptotic process involved in metanephros development Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. go-plus.json up regulation of mesenchymal cell apoptosis involved in metanephros development|upregulation of mesenchymal cell apoptosis involved in metanephros development|positive regulation of mesenchymal cell apoptosis involved in metanephros development|up-regulation of mesenchymal cell apoptosis involved in metanephros development|activation of mesenchymal cell apoptosis involved in metanephros development http://purl.obolibrary.org/obo/GO_1900213 GO:1900212 biolink:BiologicalProcess negative regulation of mesenchymal cell apoptotic process involved in metanephros development Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. go-plus.json downregulation of mesenchymal cell apoptosis involved in metanephros development|negative regulation of mesenchymal cell apoptosis involved in metanephros development|down regulation of mesenchymal cell apoptosis involved in metanephros development|inhibition of mesenchymal cell apoptosis involved in metanephros development|down-regulation of mesenchymal cell apoptosis involved in metanephros development http://purl.obolibrary.org/obo/GO_1900212 GO:1900215 biolink:BiologicalProcess negative regulation of apoptotic process involved in metanephric collecting duct development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. go-plus.json down-regulation of apoptotic process of metanephric collecting duct development|negative regulation of apoptotic process of metanephric collecting duct development|downregulation of signaling (initiator) caspase activity of metanephric collecting duct development|inhibition of type I programmed cell death of metanephric collecting duct development|downregulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic program of metanephric collecting duct development|down regulation of apoptotic process involved in metanephric collecting duct development|down-regulation of programmed cell death by apoptosis of metanephric collecting duct development|negative regulation of programmed cell death by apoptosis of metanephric collecting duct development|downregulation of apoptotic process involved in metanephric collecting duct development|downregulation of apoptotic programmed cell death of metanephric collecting duct development|down regulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic cell death of metanephric collecting duct development|downregulation of apoptotic process of metanephric collecting duct development|down regulation of type I programmed cell death of metanephric collecting duct development|negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of apoptotic programmed cell death of metanephric collecting duct development|down regulation of apoptotic process of metanephric collecting duct development|downregulation of type I programmed cell death of metanephric collecting duct development|inhibition of apoptosis of metanephric collecting duct development|down regulation of apoptotic cell death of metanephric collecting duct development|negative regulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptotic process involved in metanephric collecting duct development|inhibition of programmed cell death by apoptosis of metanephric collecting duct development|inhibition of apoptotic programmed cell death of metanephric collecting duct development|downregulation of apoptotic cell death of metanephric collecting duct development|inhibition of apoptotic process of metanephric collecting duct development|down-regulation of type I programmed cell death of metanephric collecting duct development|negative regulation of type I programmed cell death of metanephric collecting duct development|inhibition of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of programmed cell death by apoptosis of metanephric collecting duct development|inhibition of apoptotic process involved in metanephric collecting duct development|downregulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptosis of metanephric collecting duct development|negative regulation of apoptosis of metanephric collecting duct development|downregulation of programmed cell death by apoptosis of metanephric collecting duct development|down regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of apoptotic program of metanephric collecting duct development|negative regulation of apoptotic cell death of metanephric collecting duct development|down-regulation of apoptotic cell death of metanephric collecting duct development|down-regulation of apoptotic programmed cell death of metanephric collecting duct development|negative regulation of apoptotic programmed cell death of metanephric collecting duct development http://purl.obolibrary.org/obo/GO_1900215 GO:0046149 biolink:BiologicalProcess pigment catabolic process The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. go-plus.json pigment degradation|pigment breakdown|pigment catabolism http://purl.obolibrary.org/obo/GO_0046149 GO:0046148 biolink:BiologicalProcess pigment biosynthetic process The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. go-plus.json pigment biosynthesis|pigment synthesis|pigment formation|pigment anabolism http://purl.obolibrary.org/obo/GO_0046148 GO:1900214 biolink:BiologicalProcess regulation of apoptotic process involved in metanephric collecting duct development Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. go-plus.json regulation of apoptosis of metanephric collecting duct development|regulation of apoptotic programmed cell death of metanephric collecting duct development|regulation of type I programmed cell death of metanephric collecting duct development|regulation of apoptotic process of metanephric collecting duct development|regulation of apoptotic cell death of metanephric collecting duct development|regulation of apoptotic program of metanephric collecting duct development|regulation of programmed cell death by apoptosis of metanephric collecting duct development|regulation of signaling (initiator) caspase activity of metanephric collecting duct development http://purl.obolibrary.org/obo/GO_1900214 GO:0046147 biolink:BiologicalProcess tetrahydrobiopterin catabolic process The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. go-plus.json 5,6,7,8-tetrahydrobiopterin catabolic process|tetrahydrobiopterin catabolism|tetrahydrobiopterin degradation|tetrahydrobiopterin breakdown http://purl.obolibrary.org/obo/GO_0046147 GO:0061780 biolink:BiologicalProcess mitotic cohesin loading The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0061780 GO:0046146 biolink:BiologicalProcess tetrahydrobiopterin metabolic process The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. go-plus.json tetrahydrobiopterin metabolism|5,6,7,8-tetrahydrobiopterin metabolic process http://purl.obolibrary.org/obo/GO_0046146 GO:1900211 biolink:BiologicalProcess regulation of mesenchymal cell apoptotic process involved in metanephros development Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. go-plus.json regulation of mesenchymal cell apoptosis involved in metanephros development http://purl.obolibrary.org/obo/GO_1900211 GO:0061782 biolink:BiologicalProcess vesicle fusion with vesicle Fusion of the membrane of a transport vesicle with a target membrane on another vesicle. go-plus.json vesicle to vesicle fusion|vesicle-vesicle fusion http://purl.obolibrary.org/obo/GO_0061782 GO:0046145 biolink:BiologicalProcess D-alanine family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids. go-plus.json D-alanine family amino acid anabolism|D-alanine family amino acid biosynthesis|D-alanine family amino acid synthesis|D-alanine family amino acid formation http://purl.obolibrary.org/obo/GO_0046145 GO:0046144 biolink:BiologicalProcess D-alanine family amino acid metabolic process The chemical reactions and pathways involving D-alanine and related amino acids. go-plus.json D-alanine family amino acid metabolism http://purl.obolibrary.org/obo/GO_0046144 GO:0061781 biolink:BiologicalProcess mitotic cohesin unloading Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle. go-plus.json http://purl.obolibrary.org/obo/GO_0061781 GO:1900210 biolink:BiologicalProcess positive regulation of cardiolipin metabolic process Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process. go-plus.json up regulation of diphosphatidylglycerol metabolism|positive regulation of diphosphatidylglycerol metabolism|upregulation of cardiolipin metabolic process|up-regulation of diphosphatidylglycerol metabolic process|upregulation of cardiolipin metabolism|activation of diphosphatidylglycerol metabolism|activation of diphosphatidylglycerol metabolic process|up regulation of cardiolipin metabolic process|up-regulation of diphosphatidylglycerol metabolism|up-regulation of cardiolipin metabolism|positive regulation of diphosphatidylglycerol metabolic process|activation of cardiolipin metabolic process|up regulation of diphosphatidylglycerol metabolic process|activation of cardiolipin metabolism|upregulation of diphosphatidylglycerol metabolism|positive regulation of cardiolipin metabolism|up-regulation of cardiolipin metabolic process|up regulation of cardiolipin metabolism|upregulation of diphosphatidylglycerol metabolic process http://purl.obolibrary.org/obo/GO_1900210 UBERON:0012069 biolink:AnatomicalEntity epithelium-associated lymphoid tissue go-plus.json http://purl.obolibrary.org/obo/UBERON_0012069 CHEBI:11421 biolink:ChemicalSubstance 2,3-dihydrodipicolinate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_11421 chebi_ph7_3 GO:0061784 biolink:MolecularActivity peptidoglycan N-acetylglucosaminidase activity Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0061784 GO:0061783 biolink:MolecularActivity peptidoglycan muralytic activity A catalytic activity that contributes to the degradation of peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0061783 GO:0061786 biolink:MolecularActivity peptidoglycan stem peptide endopeptidase activity A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0061786 GO:0061785 biolink:MolecularActivity peptidoglycan endopeptidase activity An endopeptidase activity that uses peptidoglycan as a substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0061785 GO:0061788 biolink:MolecularActivity EGF repeat binding Binding to Epidermal Growth Factor (EGF) repeats. go-plus.json Epidermal growth factor domain binding|Epidermal Growth Factor repeat binding http://purl.obolibrary.org/obo/GO_0061788 GO:0061787 biolink:MolecularActivity peptidoglycan cross-bridge peptide endopeptidase activity A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge. go-plus.json lysostaphin activity http://purl.obolibrary.org/obo/GO_0061787 CHEBI:11424 biolink:ChemicalSubstance 2,3-dihydroxy-3-methylbutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11424 chebi_ph7_3 GO:0071109 biolink:BiologicalProcess superior temporal gyrus development The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus. go-plus.json http://purl.obolibrary.org/obo/GO_0071109 GO:0071108 biolink:BiologicalProcess protein K48-linked deubiquitination A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0071108 GO:0061789 biolink:BiologicalProcess dense core granule priming A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking. go-plus.json LDCV priming|dense core vesicle priming|large dense-core vesicle priming http://purl.obolibrary.org/obo/GO_0061789 GO:0071107 biolink:BiologicalProcess response to parathyroid hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus. go-plus.json response to parathyroid hormone stimulus http://purl.obolibrary.org/obo/GO_0071107 GO:0071106 biolink:BiologicalProcess adenosine 3',5'-bisphosphate transmembrane transport The process in which adenosine 3',5'-bisphosphate is transported across a membrane. go-plus.json adenosine 3'-phosphate-5'-phosphate transmembrane transport|adenosine 3',5'-bisphosphate membrane transport|adenosine 3',5'-diphosphate transport http://purl.obolibrary.org/obo/GO_0071106 GO:0071105 biolink:BiologicalProcess response to interleukin-11 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus. go-plus.json response to IL-11 http://purl.obolibrary.org/obo/GO_0071105 GO:0071104 biolink:BiologicalProcess response to interleukin-9 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus. go-plus.json response to IL-9 http://purl.obolibrary.org/obo/GO_0071104 GO:0071103 biolink:BiologicalProcess DNA conformation change A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. go-plus.json DNA conformation modification http://purl.obolibrary.org/obo/GO_0071103 goslim_metagenomics GO:0071102 biolink:CellularComponent alpha4-beta1 integrin-paxillin complex A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin. go-plus.json ITGA4-ITGB1-PXN complex http://purl.obolibrary.org/obo/GO_0071102 GO:0071101 biolink:CellularComponent alpha4-beta1 integrin-JAM2 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2. go-plus.json ITGA4-ITGB1-JAM2 complex http://purl.obolibrary.org/obo/GO_0071101 GO:0071100 biolink:CellularComponent alphaV-beta8 integrin-MMP14-TGFbeta-1 complex A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1). go-plus.json ITGAV-ITGB8-MMP14-TGFB1 complex http://purl.obolibrary.org/obo/GO_0071100 GO:0046154 biolink:BiologicalProcess rhodopsin metabolic process The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas. go-plus.json rhodopsin metabolism http://purl.obolibrary.org/obo/GO_0046154 GO:0046153 biolink:BiologicalProcess ommochrome catabolic process The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye. go-plus.json ommochrome degradation|ommochrome breakdown|ommochrome catabolism http://purl.obolibrary.org/obo/GO_0046153 GO:0046152 biolink:BiologicalProcess ommochrome metabolic process The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye. go-plus.json ommochrome metabolism http://purl.obolibrary.org/obo/GO_0046152 GO:0046151 biolink:BiologicalProcess eye pigment catabolic process The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye. go-plus.json eye pigment degradation|eye pigment breakdown|eye pigment catabolism http://purl.obolibrary.org/obo/GO_0046151 GO:0046150 biolink:BiologicalProcess melanin catabolic process The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. go-plus.json melanin catabolism|melanin breakdown|melanin degradation http://purl.obolibrary.org/obo/GO_0046150 GO:1900228 biolink:BiologicalProcess regulation of single-species biofilm formation in or on host organism Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism. go-plus.json http://purl.obolibrary.org/obo/GO_1900228 GO:1900227 biolink:BiologicalProcess positive regulation of NLRP3 inflammasome complex assembly Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly. go-plus.json positive regulation of NLRP3 inflammasome activation|up-regulation of NALP3 inflammasome complex assembly|activation of NLRP3 inflammasome activation|up-regulation of NLRP3 inflammasome complex assembly|upregulation of NALP3 inflammasome complex assembly|up-regulation of NLRP3 inflammasome activation|upregulation of NLRP3 inflammasome complex assembly|upregulation of NLRP3 inflammasome activation|up regulation of NALP3 inflammasome complex assembly|positive regulation of NALP3 inflammasome complex assembly|up regulation of NLRP3 inflammasome complex assembly|activation of NLRP3 inflammasome complex assembly|activation of NALP3 inflammasome complex assembly|up regulation of NLRP3 inflammasome activation http://purl.obolibrary.org/obo/GO_1900227 GO:1900229 biolink:BiologicalProcess negative regulation of single-species biofilm formation in or on host organism Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism. go-plus.json down regulation of single-species biofilm formation in or on host organism|downregulation of single-species biofilm formation in or on host organism|down-regulation of single-species biofilm formation in or on host organism|inhibition of single-species biofilm formation in or on host organism http://purl.obolibrary.org/obo/GO_1900229 GO:1900224 biolink:BiologicalProcess positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry. go-plus.json upregulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|upregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|upregulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|activation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm http://purl.obolibrary.org/obo/GO_1900224 GO:1900223 biolink:BiologicalProcess positive regulation of amyloid-beta clearance Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance. go-plus.json up regulation of beta-amyloid clearance|upregulation of beta-amyloid clearance|positive regulation of beta-amyloid clearance|up-regulation of beta-amyloid clearance|activation of beta-amyloid clearance http://purl.obolibrary.org/obo/GO_1900223 GO:1900226 biolink:BiologicalProcess negative regulation of NLRP3 inflammasome complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly. go-plus.json down-regulation of NLRP3 inflammasome activation|negative regulation of NLRP3 inflammasome activation|inhibition of NLRP3 inflammasome complex assembly|inhibition of NALP3 inflammasome complex assembly|down regulation of NALP3 inflammasome complex assembly|inhibition of NLRP3 inflammasome activation|downregulation of NALP3 inflammasome complex assembly|down regulation of NLRP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome complex assembly|down regulation of NLRP3 inflammasome activation|negative regulation of NALP3 inflammasome complex assembly|down-regulation of NALP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome activation|down-regulation of NLRP3 inflammasome complex assembly http://purl.obolibrary.org/obo/GO_1900226 UBERON:0012054 biolink:AnatomicalEntity myocoele The cavity within a myotome go-plus.json http://purl.obolibrary.org/obo/UBERON_0012054 GO:1900225 biolink:BiologicalProcess regulation of NLRP3 inflammasome complex assembly Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly. go-plus.json regulation of NALP3 inflammasome complex assembly|regulation of NLRP3 inflammasome activation http://purl.obolibrary.org/obo/GO_1900225 GO:0046159 biolink:BiologicalProcess ocellus pigment catabolic process The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates. go-plus.json ocellus pigment degradation|ocellus pigment breakdown|ocellus pigment catabolism http://purl.obolibrary.org/obo/GO_0046159 GO:0046158 biolink:BiologicalProcess ocellus pigment metabolic process The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates. go-plus.json ocellus pigment metabolism http://purl.obolibrary.org/obo/GO_0046158 GO:1900220 biolink:BiologicalProcess semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis. go-plus.json semaphorin-plexin signalling pathway of bone trabecula morphogenesis|semaphorin-plexin signaling pathway of bone trabecula morphogenesis http://purl.obolibrary.org/obo/GO_1900220 GO:0046157 biolink:BiologicalProcess siroheme catabolic process The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings. go-plus.json siroheme degradation|siroheme breakdown|siroheme catabolism|sirohaem catabolism|sirohaem catabolic process http://purl.obolibrary.org/obo/GO_0046157 GO:0046156 biolink:BiologicalProcess siroheme metabolic process The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings. go-plus.json siroheme metabolism|sirohaem metabolic process|sirohaem metabolism http://purl.obolibrary.org/obo/GO_0046156 GO:1900222 biolink:BiologicalProcess negative regulation of amyloid-beta clearance Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance. go-plus.json down-regulation of beta-amyloid clearance|downregulation of beta-amyloid clearance|down regulation of beta-amyloid clearance|inhibition of beta-amyloid clearance|negative regulation of beta-amyloid clearance http://purl.obolibrary.org/obo/GO_1900222 GO:0061771 biolink:BiologicalProcess response to caloric restriction A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake. go-plus.json http://purl.obolibrary.org/obo/GO_0061771 GO:1900221 biolink:BiologicalProcess regulation of amyloid-beta clearance Any process that modulates the frequency, rate or extent of amyloid-beta clearance. go-plus.json regulation of beta-amyloid clearance http://purl.obolibrary.org/obo/GO_1900221 GO:0046155 biolink:BiologicalProcess rhodopsin catabolic process The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas. go-plus.json rhodopsin breakdown|rhodopsin catabolism|rhodopsin degradation http://purl.obolibrary.org/obo/GO_0046155 GO:0061770 biolink:MolecularActivity translation elongation factor binding Binding to a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation. go-plus.json http://purl.obolibrary.org/obo/GO_0061770 GO:0061773 biolink:CellularComponent eNoSc complex A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation. go-plus.json energy dependent nucleolar silencing complex http://purl.obolibrary.org/obo/GO_0061773 GO:0061772 biolink:BiologicalProcess xenobiotic transport across blood-nerve barrier The directed movement of a xenobiotic through the blood-nerve barrier. go-plus.json drug transport across blood-nerve barrier|drug transport across perineurial barrier http://purl.obolibrary.org/obo/GO_0061772 GO:0061775 biolink:MolecularActivity cohesin loading activity Facilitating a conformational change to load a cohesin complex around sister chromatids, driven by ATP hydrolysis. go-plus.json cohesin ATPase activity|ATP-dependent cohesin loading activity|cohesin loading ATPase http://purl.obolibrary.org/obo/GO_0061775 GO:0061774 biolink:BiologicalProcess cohesin unloading Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA. go-plus.json DNA exit from the cohesin ring http://purl.obolibrary.org/obo/GO_0061774 GO:0061777 biolink:MolecularActivity obsolete DNA clamp activity OBSOLETE. A DNA binding activity in which a protein complex interacts selectively and non-covalently with single DNA duplex to tightly encircle the DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0061777 GO:0061776 biolink:MolecularActivity topological DNA co-entrapment activity A DNA binding activity in which a protein complex interacts with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring. go-plus.json topological DNA entrapment activity http://purl.obolibrary.org/obo/GO_0061776 CHEBI:11412 biolink:ChemicalSubstance (2R,3S,4S)-leucocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_11412 chebi_ph7_3 GO:0061779 biolink:CellularComponent Tapasin-ERp57 complex Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role. go-plus.json http://purl.obolibrary.org/obo/GO_0061779 GO:0061778 biolink:MolecularActivity intracellular chloride channel activity Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. go-plus.json http://purl.obolibrary.org/obo/GO_0061778 CHEBI:74986 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74986 chebi_ph7_3 CHEBI:84305 biolink:ChemicalSubstance 2-carboxyhexacosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84305 CHEBI:84303 biolink:ChemicalSubstance 2-carboxytetracosanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84303 CHEBI:84302 biolink:ChemicalSubstance trilinoleoyl 2-monolysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_84302 CHEBI:60344 biolink:ChemicalSubstance ferroheme b(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60344 chebi_ph7_3 CHEBI:84300 biolink:ChemicalSubstance 1-myristoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84300 chebi_ph7_3 CHEBI:60345 biolink:ChemicalSubstance organic phosphoramidate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60345 CHEBI:35378 biolink:ChemicalSubstance glycosylfructose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35378 CHEBI:35371 biolink:ChemicalSubstance lipooligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35371 CHEBI:35373 biolink:ChemicalSubstance D-glucosaminide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35373 CHEBI:35372 biolink:ChemicalSubstance D-fuconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35372 chebi_ph7_3 CHEBI:35375 biolink:ChemicalSubstance alditol 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35375 CHEBI:59345 biolink:ChemicalSubstance 5,6,7,8-tetrahydrosarcinapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59345 CHEBI:35374 biolink:ChemicalSubstance D-mannose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35374 UBERON:0002749 biolink:AnatomicalEntity regional part of cerebellar cortex A regional part of brain that is part of a cerebellar cortex [Automatically generated definition]. go-plus.json cerebellar cortical segment|segment of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0002749 CHEBI:74997 biolink:ChemicalSubstance mannosyl diphosphorylinositol ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74997 chebi_ph7_3 CHEBI:84317 biolink:ChemicalSubstance 1-acyl-2-stearoyl-sn-glycero-3-phospho-(1D-myo-inositol) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84317 CHEBI:84315 biolink:ChemicalSubstance L-arginyl-L-alpha-amino acid(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84315 chebi_ph7_3 CHEBI:84312 biolink:ChemicalSubstance dodecanoyl-AMP go-plus.json http://purl.obolibrary.org/obo/CHEBI_84312 CHEBI:84311 biolink:ChemicalSubstance bacilysin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84311 chebi_ph7_3 CHEBI:84310 biolink:ChemicalSubstance anticapsin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84310 chebi_ph7_3 CHEBI:35387 biolink:ChemicalSubstance L-idarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35387 CHEBI:142607 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142607 chebi_ph7_3 CHEBI:35389 biolink:ChemicalSubstance altrarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35389 CHEBI:60356 biolink:ChemicalSubstance tetraoleyl cardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60356 NCBITaxon:71240 biolink:OrganismalEntity eudicotyledons go-plus.json Dicotyledoneae|dicots|eudicots|dicotyledons http://purl.obolibrary.org/obo/NCBITaxon_71240 CHEBI:59338 biolink:ChemicalSubstance methylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_59338 chebi_ph7_3 CHEBI:35381 biolink:ChemicalSubstance monosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35381 CHEBI:35384 biolink:ChemicalSubstance idarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35384 CHEBI:35386 biolink:ChemicalSubstance D-idarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35386 CHEBI:74994 biolink:ChemicalSubstance Man-1-6-Ins-1-P-Cer C(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74994 chebi_ph7_3 CHEBI:35385 biolink:ChemicalSubstance idarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35385 CHEBI:11392 biolink:ChemicalSubstance 2'-(5-triphosphoribosyl)-3'-dephospho-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_11392 CHEBI:50996 biolink:ChemicalSubstance tertiary amino compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_50996 CHEBI:50995 biolink:ChemicalSubstance secondary amino compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_50995 CHEBI:50994 biolink:ChemicalSubstance primary amino compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_50994 CHEBI:50998 biolink:ChemicalSubstance trans-2-enoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_50998 CHEBI:60362 biolink:ChemicalSubstance (KDO)3-lipid IVA go-plus.json http://purl.obolibrary.org/obo/CHEBI_60362 CHEBI:60364 biolink:ChemicalSubstance (KDO)-lipid IVA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60364 chebi_ph7_3 NCBITaxon:71275 biolink:OrganismalEntity rosids go-plus.json Rosidae http://purl.obolibrary.org/obo/NCBITaxon_71275 CHEBI:84322 biolink:ChemicalSubstance dapdiamide C zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84322 chebi_ph7_3 CHEBI:60365 biolink:ChemicalSubstance (KDO)2-lipid IVA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60365 chebi_ph7_3 CHEBI:84321 biolink:ChemicalSubstance dapdiamide B zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84321 chebi_ph7_3 NCBITaxon:71274 biolink:OrganismalEntity asterids go-plus.json Asteridae http://purl.obolibrary.org/obo/NCBITaxon_71274 CHEBI:84320 biolink:ChemicalSubstance dapdiamide A zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84320 chebi_ph7_3 CHEBI:60367 biolink:ChemicalSubstance (KDO)3-lipid IVA(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60367 chebi_ph7_3 CHEBI:35356 biolink:ChemicalSubstance dicarboximide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35356 chebi_ph7_3 CHEBI:35359 biolink:ChemicalSubstance carboxamidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35359 CHEBI:35358 biolink:ChemicalSubstance sulfonamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35358 chebi_ph7_3 CHEBI:60369 biolink:ChemicalSubstance trans,poly-cis-decaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60369 chebi_ph7_3 GO:0061900 biolink:BiologicalProcess glial cell activation A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0061900 GO:0061902 biolink:BiologicalProcess negative regulation of 1-phosphatidylinositol-3-kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061902 GO:0061901 biolink:BiologicalProcess regulation of 1-phosphatidylinositol-3-kinase activity Any process that modulates the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061901 GO:0061903 biolink:BiologicalProcess positive regulation of 1-phosphatidylinositol-3-kinase activity Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061903 UBERON:0002743 biolink:AnatomicalEntity basal forebrain A region of the brain consisting of ventral and rostral subcortical regions of the telencephalon, including among others, the basal ganglia, septal nuclei, amygdala, ventral pallidum, substantia innominata, and basal nucleus of Meynert. go-plus.json basal forebrain area|pars basalis telencephali http://purl.obolibrary.org/obo/UBERON_0002743 GO:0061906 biolink:BiologicalProcess autophagosome localization Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061906 CHEBI:59326 biolink:ChemicalSubstance prostaglandin carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59326 CHEBI:35350 biolink:ChemicalSubstance hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35350 CHEBI:35353 biolink:ChemicalSubstance isocyanide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35353 GO:0061908 biolink:CellularComponent phagophore A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle. go-plus.json isolation membrane http://purl.obolibrary.org/obo/GO_0061908 GO:0061907 biolink:BiologicalProcess negative regulation of AMPA receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061907 CHEBI:35352 biolink:ChemicalSubstance organonitrogen compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35352 UBERON:0002726 biolink:AnatomicalEntity cervical spinal cord A spinal cord segment that adjacent_to a cervical region. go-plus.json cervical segments of spinal cord [1-8]|pars cervicalis medullae spinalis|cervical segment of spinal cord|segmenta cervicalia medullae spinalis [1-8|cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0002726 CHEBI:60373 biolink:ChemicalSubstance lipid IVA oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60373 CHEBI:84335 biolink:ChemicalSubstance 2-hydroxymyristate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84335 chebi_ph7_3 CHEBI:60374 biolink:ChemicalSubstance 2-cis,6-cis-farnesyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60374 chebi_ph7_3 CHEBI:60377 biolink:ChemicalSubstance cytidine 5'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60377 chebi_ph7_3 CHEBI:35366 biolink:ChemicalSubstance fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35366 CHEBI:84331 biolink:ChemicalSubstance N(3)-fumaramoyl-(S)-2,3-diaminopropanoic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84331 chebi_ph7_3 CHEBI:35368 biolink:ChemicalSubstance hexasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35368 CHEBI:84330 biolink:ChemicalSubstance N(3)-fumaroyl-(S)-2,3-diaminopropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84330 chebi_ph7_3 CHEBI:35367 biolink:ChemicalSubstance thiocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35367 CHEBI:35369 biolink:ChemicalSubstance pentasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35369 UBERON:0002731 biolink:AnatomicalEntity vestibulocochlear nerve root Either of the two roots that come of the vestibulocochlear nerve go-plus.json vestibulocochlear nerve roots|statoacoustic nerve fibers|fibrae nervi statoacustici|vestibulocochlear nerve fibers|central part of vestibulocochlear nerve|root of vestibulocochlear nerve|vestibulocochlear nerve tract http://purl.obolibrary.org/obo/UBERON_0002731 CHEBI:50981 biolink:ChemicalSubstance secondary aliphatic amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50981 CHEBI:59314 biolink:ChemicalSubstance alpha-D-Galp-(1->4)-beta-D-Galp go-plus.json http://purl.obolibrary.org/obo/CHEBI_59314 chebi_ph7_3 CHEBI:50972 biolink:ChemicalSubstance 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50972 CHEBI:60384 biolink:ChemicalSubstance N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60384 chebi_ph7_3 UBERON:0012125 biolink:AnatomicalEntity dermatological-muscosal system Anatomical system that consists of the integumental system plus all mucosae and submucosae. go-plus.json dermatological system http://purl.obolibrary.org/obo/UBERON_0012125 CHEBI:84346 biolink:ChemicalSubstance cholesteryl all-cis-icosa-8,11,14-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84346 chebi_ph7_3 CHEBI:49983 biolink:ChemicalSubstance 3-aminoalaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49983 CHEBI:60386 biolink:ChemicalSubstance ditrans,polycis-dodecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60386 chebi_ph7_3 CHEBI:60385 biolink:ChemicalSubstance ditrans,polycis-tridecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60385 chebi_ph7_3 CHEBI:84345 biolink:ChemicalSubstance methyl nogalonate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84345 chebi_ph7_3 CHEBI:60388 biolink:ChemicalSubstance tri-trans,poly-cis-undecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60388 chebi_ph7_3 CHEBI:35333 biolink:ChemicalSubstance 4-(4-deoxy-D-gluc-4-enosyluronic acid)-D-galacturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35333 CHEBI:60387 biolink:ChemicalSubstance ditrans,polycis-tetradecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60387 chebi_ph7_3 CHEBI:84342 biolink:ChemicalSubstance nogalaviketone(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84342 chebi_ph7_3 CHEBI:84341 biolink:ChemicalSubstance cholesteryl linolenate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84341 chebi_ph7_3 CHEBI:60389 biolink:ChemicalSubstance alpha-L-galactose 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60389 chebi_ph7_3 GO:0061920 biolink:MolecularActivity protein propionyltransferase activity Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide. go-plus.json http://purl.obolibrary.org/obo/GO_0061920 CHEBI:35337 biolink:ChemicalSubstance central nervous system stimulant go-plus.json http://purl.obolibrary.org/obo/CHEBI_35337 CHEBI:11369 biolink:ChemicalSubstance 1L-myo-inositol 1,2,3,4,6-pentakisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11369 GO:0061922 biolink:MolecularActivity histone propionyltransferase activity Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone. go-plus.json http://purl.obolibrary.org/obo/GO_0061922 GO:0061921 biolink:BiologicalProcess peptidyl-lysine propionylation The propionylation of peptidyl-lysine. go-plus.json http://purl.obolibrary.org/obo/GO_0061921 CHEBI:35338 biolink:ChemicalSubstance amphetamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_35338 GO:0061924 biolink:BiologicalProcess regulation of formation of radial glial scaffolds Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells. go-plus.json regulation of radial glial scaffold formation|regulation of Bergmann fiber biosynthesis|regulation of Bergmann fiber formation http://purl.obolibrary.org/obo/GO_0061924 GO:0061923 biolink:MolecularActivity (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene. go-plus.json protoillud-7-ene synthase activity http://purl.obolibrary.org/obo/GO_0061923 GO:0061926 biolink:BiologicalProcess positive regulation of formation of radial glial scaffolds Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds. go-plus.json positive regulation of radial glial scaffold formation|positive regulation of Bergmann fiber formation|positive regulation of Bergmann fiber biosynthesis http://purl.obolibrary.org/obo/GO_0061926 GO:0061925 biolink:BiologicalProcess negative regulation of formation of radial glial scaffolds Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells. go-plus.json negative regulation of Bergmann fiber formation|negative regulation of radial glial scaffold formation|negative regulation of Bergmann fiber biosynthesis http://purl.obolibrary.org/obo/GO_0061925 GO:0061928 biolink:MolecularActivity glutathione specific gamma-glutamylcyclotransferase activity Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine. EC:4.3.2.7|RHEA:47724 go-plus.json http://purl.obolibrary.org/obo/GO_0061928 GO:0061927 biolink:CellularComponent TOC-TIC supercomplex I The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110. go-plus.json http://purl.obolibrary.org/obo/GO_0061927 CHEBI:35331 biolink:ChemicalSubstance rhodopin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35331 chebi_ph7_3 GO:0061929 biolink:MolecularActivity gamma-glutamylaminecyclotransferase activity Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline. EC:4.3.2.8|RHEA:16961 go-plus.json http://purl.obolibrary.org/obo/GO_0061929 CHEBI:35330 biolink:ChemicalSubstance spheroidene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35330 chebi_ph7_3 GO:0061909 biolink:BiologicalProcess autophagosome-lysosome fusion The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome. go-plus.json autophagosome-vacuole fusion|autophagosome fusion http://purl.obolibrary.org/obo/GO_0061909 CHEBI:50967 biolink:ChemicalSubstance non-covalently-bound molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_50967 CHEBI:60390 biolink:ChemicalSubstance D-alanyl-D-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60390 chebi_ph7_3 CHEBI:60392 biolink:ChemicalSubstance ditrans,polycis-undecaprenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60392 chebi_ph7_3 CHEBI:84359 biolink:ChemicalSubstance 3-hydroxy-2,4-dioxopentyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84359 chebi_ph7_3 CHEBI:84358 biolink:ChemicalSubstance L-dihydroanticapsin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84358 chebi_ph7_3 CHEBI:84355 biolink:ChemicalSubstance 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84355 chebi_ph7_3 CHEBI:35344 biolink:ChemicalSubstance 21-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35344 CHEBI:35343 biolink:ChemicalSubstance 17beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35343 CHEBI:84354 biolink:ChemicalSubstance (4R)-3,4-dihydro-4-hydroxyphenylpyruvate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84354 chebi_ph7_3 CHEBI:35346 biolink:ChemicalSubstance 11beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35346 chebi_ph7_3 CHEBI:35348 biolink:ChemicalSubstance 3beta-sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35348 chebi_ph7_3 CHEBI:35347 biolink:ChemicalSubstance 3alpha-sterol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35347 GO:0061911 biolink:BiologicalProcess amphisome-lysosome fusion The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome. go-plus.json http://purl.obolibrary.org/obo/GO_0061911 GO:0061910 biolink:BiologicalProcess autophagosome-endosome fusion The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome. go-plus.json http://purl.obolibrary.org/obo/GO_0061910 CHEBI:35349 biolink:ChemicalSubstance 7beta-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35349 chebi_ph7_3 GO:0061913 biolink:BiologicalProcess positive regulation of growth plate cartilage chondrocyte proliferation Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0061913 GO:0061912 biolink:BiologicalProcess selective autophagy The macroautophagy process in which specific structures are targeted by the autophagy process. go-plus.json http://purl.obolibrary.org/obo/GO_0061912 GO:0061915 biolink:BiologicalProcess actin fusion focus localization Any process in which an actin fusion focus are transported to, or maintained in, a specific location. The actin fusion focus is an aster-like, F-actin-containing structure at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. go-plus.json actin fusion focus localisation http://purl.obolibrary.org/obo/GO_0061915 GO:0061914 biolink:BiologicalProcess negative regulation of growth plate cartilage chondrocyte proliferation Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0061914 GO:0061917 biolink:CellularComponent leading edge of dendritic growth cone That part of the dendritic growth cone which represents the distal part of the structure. go-plus.json dendritic growth cone leading edge|distal tip of dendritic growth cone http://purl.obolibrary.org/obo/GO_0061917 CHEBI:35340 biolink:ChemicalSubstance methamphetamine hydrochloride go-plus.json http://purl.obolibrary.org/obo/CHEBI_35340 GO:0061916 biolink:CellularComponent leading edge of axonal growth cone That part of the axonal growth cone which represents the distal part of the structure. go-plus.json axonal growth cone leading edge|distal tip of axonal growth cone http://purl.obolibrary.org/obo/GO_0061916 GO:0061919 biolink:BiologicalProcess process utilizing autophagic mechanism A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0061919 gocheck_do_not_annotate CHEBI:35342 biolink:ChemicalSubstance 17alpha-hydroxy steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35342 CHEBI:35341 biolink:ChemicalSubstance steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35341 chebi_ph7_3 CHEBI:50956 biolink:ChemicalSubstance organoarsonic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_50956 CHEBI:50955 biolink:ChemicalSubstance arsonic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_50955 CHEBI:25998 biolink:ChemicalSubstance 3-phenyllactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25998 GO:0046305 biolink:BiologicalProcess alkanesulfonate biosynthetic process The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. go-plus.json alkanesulfonate formation|alkanesulfonate biosynthesis|alkanesulphonate biosynthesis|alkanesulphonate biosynthetic process|alkanesulfonate anabolism|alkanesulfonate synthesis http://purl.obolibrary.org/obo/GO_0046305 GO:0046304 biolink:BiologicalProcess 2-nitropropane catabolic process The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. go-plus.json 2-nitropropane degradation|2-nitropropane breakdown|2-nitropropane catabolism http://purl.obolibrary.org/obo/GO_0046304 CHEBI:35318 biolink:ChemicalSubstance glycosylmannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35318 GO:0046303 biolink:BiologicalProcess obsolete 2-nitropropane biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. go-plus.json 2-nitropropane synthesis|2-nitropropane formation|2-nitropropane biosynthetic process|2-nitropropane anabolism|2-nitropropane biosynthesis http://purl.obolibrary.org/obo/GO_0046303 GO:0046302 biolink:BiologicalProcess 2-chloro-N-isopropylacetanilide catabolic process The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants. go-plus.json 2-chloro-N-isopropylacetanilide degradation|2-chloro-N-isopropylacetanilide breakdown|2-chloro-N-isopropylacetanilide catabolism http://purl.obolibrary.org/obo/GO_0046302 GO:0046301 biolink:BiologicalProcess obsolete 2-chloro-N-isopropylacetanilide biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants. go-plus.json 2-chloro-N-isopropylacetanilide synthesis|2-chloro-N-isopropylacetanilide formation|2-chloro-N-isopropylacetanilide biosynthetic process|2-chloro-N-isopropylacetanilide anabolism|2-chloro-N-isopropylacetanilide biosynthesis http://purl.obolibrary.org/obo/GO_0046301 GO:0046300 biolink:BiologicalProcess 2,4-dichlorophenoxyacetic acid catabolic process The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. go-plus.json 2,4-dichlorophenoxyacetic acid degradation|2,4-dichlorophenoxyacetic acid breakdown|2,4-dichlorophenoxyacetic acid catabolism http://purl.obolibrary.org/obo/GO_0046300 CHEBI:25990 biolink:ChemicalSubstance phenylethanolamines go-plus.json http://purl.obolibrary.org/obo/CHEBI_25990 CHEBI:35311 biolink:ChemicalSubstance carotenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35311 CHEBI:35310 biolink:ChemicalSubstance carotenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_35310 CHEBI:35313 biolink:ChemicalSubstance hexoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_35313 GO:0061940 biolink:BiologicalProcess regulation of c-di-GMP signaling Any process that modulates the rate frequency or extent of c-di-GMP signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0061940 CHEBI:35312 biolink:ChemicalSubstance pentoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_35312 CHEBI:84363 biolink:ChemicalSubstance acarbose(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84363 chebi_ph7_3 GO:0046309 biolink:BiologicalProcess 1,3-dichloro-2-propanol biosynthetic process The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. go-plus.json 1,3-dichloro-2-propanol anabolism|1,3-dichloro-2-propanol synthesis|1,3-dichloro-2-propanol formation|1,3-dichloro-2-propanol biosynthesis http://purl.obolibrary.org/obo/GO_0046309 GO:0061942 biolink:BiologicalProcess negative regulation of c-di-GMP signaling Any process that decreases the rate, frequency or extent of c-di-GMP signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0061942 CHEBI:35315 biolink:ChemicalSubstance deoxy hexoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_35315 CHEBI:84362 biolink:ChemicalSubstance 2-epi-5-epi-valiolone 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84362 chebi_ph7_3 GO:0046308 biolink:BiologicalProcess Z-phenylacetaldoxime catabolic process The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds. go-plus.json Z-phenylacetaldoxime degradation|Z-phenylacetaldoxime breakdown|Z-phenylacetaldoxime catabolism http://purl.obolibrary.org/obo/GO_0046308 GO:0061941 biolink:BiologicalProcess positive regulation of c-di-GMP signaling Any process that increases the rate, frequency or extent of c-di-GMP signaling. go-plus.json http://purl.obolibrary.org/obo/GO_0061941 CHEBI:35314 biolink:ChemicalSubstance glycosiduronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35314 CHEBI:84361 biolink:ChemicalSubstance 5-epi-valiolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84361 chebi_ph7_3 GO:0046307 biolink:BiologicalProcess Z-phenylacetaldoxime biosynthetic process The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds. go-plus.json Z-phenylacetaldoxime anabolism|Z-phenylacetaldoxime synthesis|Z-phenylacetaldoxime formation|Z-phenylacetaldoxime biosynthesis http://purl.obolibrary.org/obo/GO_0046307 GO:0061944 biolink:BiologicalProcess negative regulation of protein K48-linked ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. go-plus.json http://purl.obolibrary.org/obo/GO_0061944 CHEBI:35317 biolink:ChemicalSubstance glycosylgalactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35317 GO:0046306 biolink:BiologicalProcess alkanesulfonate catabolic process The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. go-plus.json alkanesulfonate catabolism|alkanesulphonate catabolic process|alkanesulphonate catabolism|alkanesulfonate degradation|alkanesulfonate breakdown http://purl.obolibrary.org/obo/GO_0046306 UBERON:0002786 biolink:AnatomicalEntity root of abducens nerve Nerve fibers arising from motor neurons in the abducens nucleus that are contained within the pontine tegmentum go-plus.json root of abducens nerve|central part of abducens nerve|abducens nerve/root|abducens nerve fibers|fibrae nervi abducentis|abducens nerve root|abducens nerve tract http://purl.obolibrary.org/obo/UBERON_0002786 NCBITaxon:71239 biolink:OrganismalEntity Cucurbitales go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_71239 GO:0061945 biolink:BiologicalProcess regulation of protein K48-linked ubiquitination Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. go-plus.json http://purl.obolibrary.org/obo/GO_0061945 GO:0061948 biolink:BiologicalProcess premature acrosome loss The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents. go-plus.json spontaneous acrosome loss http://purl.obolibrary.org/obo/GO_0061948 UBERON:0002787 biolink:AnatomicalEntity decussation of trochlear nerve the crossing of the two trochlear nerves at their exit through the velum medullare anterius. go-plus.json decussation of the trochlear nerve|decussation of trochlear nerve fibers|trochlear nerve decussation|trochlear neural decussation|trochlear decussation|decussatio fibrarum nervorum trochlearium|decussation of trochlear nerve (IV)|decussatio nervorum trochlearium|decussatio trochlearis http://purl.obolibrary.org/obo/UBERON_0002787 GO:0061949 biolink:BiologicalProcess regulation of premature acrosome loss Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents. go-plus.json http://purl.obolibrary.org/obo/GO_0061949 UBERON:0002768 biolink:AnatomicalEntity vestibulospinal tract A long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord[GO]. go-plus.json tractus vestibulospinalis|vestibulo-spinal tracts|vestibulospinal pathway|vestibulo-spinal tract|vestibulospinal tracts http://purl.obolibrary.org/obo/UBERON_0002768 UBERON:0002769 biolink:AnatomicalEntity superior temporal gyrus Component of the temporal lobe, lateral aspect. The rostral boundary is the rostral extent of the ssuperior temporal sulcus. The caudal boundary is the cauday portion of the superior temporal gyrus (posterior to becoming continuous with the supramarginal gyrus). The medial boundary is the lateral fissure (and when present the supramarginal gyrus), and the lateral boundary is the superior temporal suclus (Christine Fennema-Notestine). go-plus.json gyrus temporalis superior|gyrus temporalis superior http://purl.obolibrary.org/obo/UBERON_0002769 GO:0046316 biolink:MolecularActivity gluconokinase activity Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+). KEGG_REACTION:R01737|EC:2.7.1.12|RHEA:19433|MetaCyc:GLUCONOKIN-RXN go-plus.json gluconate kinase activity|gluconokinase (phosphorylating)|ATP:D-gluconate 6-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0046316 CHEBI:50949 biolink:ChemicalSubstance serotonin uptake inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50949 GO:0046315 biolink:BiologicalProcess phosphocreatine catabolic process The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase. go-plus.json phosphocreatine catabolism|phosphocreatine degradation|phosphocreatine breakdown http://purl.obolibrary.org/obo/GO_0046315 CHEBI:35329 biolink:ChemicalSubstance carotenoid ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_35329 CHEBI:50948 biolink:ChemicalSubstance (2S,3S)-2-methylcitric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50948 GO:0046314 biolink:BiologicalProcess phosphocreatine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase. go-plus.json phosphocreatine biosynthesis|phosphocreatine anabolism|phosphocreatine synthesis|phosphocreatine formation http://purl.obolibrary.org/obo/GO_0046314 GO:0046313 biolink:BiologicalProcess phosphoarginine catabolic process The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine. go-plus.json phosphoarginine catabolism|phosphoarginine degradation|phosphoarginine breakdown http://purl.obolibrary.org/obo/GO_0046313 GO:0046312 biolink:BiologicalProcess phosphoarginine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine. go-plus.json phosphoarginine anabolism|phosphoarginine synthesis|phosphoarginine formation|phosphoarginine biosynthesis http://purl.obolibrary.org/obo/GO_0046312 GO:0046311 biolink:BiologicalProcess prenylcysteine biosynthetic process The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue. go-plus.json prenylcysteine biosynthesis|prenylcysteine anabolism|prenylcysteine synthesis|prenylcysteine formation http://purl.obolibrary.org/obo/GO_0046311 GO:0046310 biolink:BiologicalProcess 1,3-dichloro-2-propanol catabolic process The chemical reactions and pathways resulting in the breakdown of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. go-plus.json 1,3-dichloro-2-propanol degradation|1,3-dichloro-2-propanol catabolism|1,3-dichloro-2-propanol breakdown http://purl.obolibrary.org/obo/GO_0046310 CHEBI:35324 biolink:ChemicalSubstance hydrazinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35324 CHEBI:84374 biolink:ChemicalSubstance 3-ammonio-L-alanine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84374 CHEBI:35323 biolink:ChemicalSubstance N-substituted amine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35323 GO:0061931 biolink:BiologicalProcess positive regulation of erythrocyte enucleation Any process that increases the frequency, rate or extent of erythrocyte enucleation. go-plus.json http://purl.obolibrary.org/obo/GO_0061931 GO:0061930 biolink:BiologicalProcess regulation of erythrocyte enucleation Any process that modulates the frequency, rate or extent of erythrocyte enucleation. go-plus.json http://purl.obolibrary.org/obo/GO_0061930 GO:0046319 biolink:BiologicalProcess positive regulation of glucosylceramide biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide. go-plus.json up regulation of glucosylceramide biosynthetic process|activation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide biosynthesis|stimulation of glucosylceramide biosynthetic process|up-regulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide anabolism|upregulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide synthesis|positive regulation of glucosylceramide formation http://purl.obolibrary.org/obo/GO_0046319 CHEBI:35325 biolink:ChemicalSubstance hydrazinium(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35325 GO:0046318 biolink:BiologicalProcess negative regulation of glucosylceramide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide. go-plus.json downregulation of glucosylceramide biosynthetic process|down-regulation of glucosylceramide biosynthetic process|negative regulation of glucosylceramide biosynthesis|inhibition of glucosylceramide biosynthetic process|negative regulation of glucosylceramide anabolism|negative regulation of glucosylceramide synthesis|negative regulation of glucosylceramide formation|down regulation of glucosylceramide biosynthetic process http://purl.obolibrary.org/obo/GO_0046318 CHEBI:35328 biolink:ChemicalSubstance spirilloxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35328 chebi_ph7_3 GO:0046317 biolink:BiologicalProcess regulation of glucosylceramide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide. go-plus.json regulation of glucosylceramide synthesis|regulation of glucosylceramide formation|regulation of glucosylceramide anabolism|regulation of glucosylceramide biosynthesis http://purl.obolibrary.org/obo/GO_0046317 GO:0061932 biolink:BiologicalProcess negative regulation of erythrocyte enucleation Any process that decreases the frequency, rate or extent of erythrocyte enucleation. go-plus.json http://purl.obolibrary.org/obo/GO_0061932 GO:0061935 biolink:BiologicalProcess fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes. go-plus.json http://purl.obolibrary.org/obo/GO_0061935 GO:0061934 biolink:BiologicalProcess regulation of adenine biosynthetic process Any process that modulates the frequency, rate or extent of an adenine biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_0061934 GO:0061936 biolink:BiologicalProcess fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm. go-plus.json http://purl.obolibrary.org/obo/GO_0061936 UBERON:0002776 biolink:AnatomicalEntity ventral nuclear group Nuclei in the ventral part of the thalamus, involved in modulating activity of dorsal thalamic nuclei. go-plus.json ventral nuclear group of thalamus|ventral nuclei of thalamus|ventral dorsal thalamic nuclear group|ventral thalamus nucleus|ventral group of the dorsal thalamus|ventral nuclear group|ventral tier thalamic nuclei|nuclei ventrales thalami|ventral nuclear mass|VNG|ventral group of dorsal thalamus|dorsal thalamus, ventral group http://purl.obolibrary.org/obo/UBERON_0002776 GO:0061939 biolink:BiologicalProcess c-di-GMP signaling Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal. go-plus.json cyclic diguanylate signaling|cyclic di-GMP signaling|cyclic di-(3':5')-guanosine monophosphate signaling|3',5'-cyclic di-GMP signaling http://purl.obolibrary.org/obo/GO_0061939 UBERON:0002770 biolink:AnatomicalEntity posterior hypothalamic region The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat. go-plus.json posterior hypothalamus|mammillary level of hypothalamus|hypothalamus posterior|PHR|mammillary region|regio hypothalamica posterior http://purl.obolibrary.org/obo/UBERON_0002770 GO:0061938 biolink:BiologicalProcess protein localization to somatodendritic compartment A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. go-plus.json somatodendritic protein localization http://purl.obolibrary.org/obo/GO_0061938 CHEBI:74901 biolink:ChemicalSubstance 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74901 chebi_ph7_3 CHEBI:74900 biolink:ChemicalSubstance N(4)-acetylcytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74900 chebi_ph7_3 CHEBI:74903 biolink:ChemicalSubstance isocaproic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_74903 CHEBI:74902 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74902 chebi_ph7_3 CHEBI:74905 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74905 chebi_ph7_3 CHEBI:74904 biolink:ChemicalSubstance isocaproate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74904 chebi_ph7_3 CHEBI:74909 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74909 chebi_ph7_3 GO:1900198 biolink:BiologicalProcess positive regulation of penicillin biosynthetic process Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process. go-plus.json upregulation of penicillin synthesis|upregulation of penicillin formation|up regulation of penicillin biosynthesis|up regulation of penicillin biosynthetic process|up-regulation of penicillin anabolism|activation of penicillin biosynthetic process|positive regulation of penicillin biosynthesis|up-regulation of penicillin synthesis|activation of penicillin biosynthesis|activation of penicillin anabolism|up-regulation of penicillin formation|activation of penicillin synthesis|positive regulation of penicillin anabolism|up-regulation of penicillin biosynthesis|up-regulation of penicillin biosynthetic process|activation of penicillin formation|up regulation of penicillin anabolism|positive regulation of penicillin synthesis|up regulation of penicillin synthesis|positive regulation of penicillin formation|up regulation of penicillin formation|upregulation of penicillin biosynthetic process|upregulation of penicillin biosynthesis|upregulation of penicillin anabolism http://purl.obolibrary.org/obo/GO_1900198 GO:1900197 biolink:BiologicalProcess negative regulation of penicillin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process. go-plus.json inhibition of penicillin anabolism|down regulation of penicillin formation|downregulation of penicillin biosynthetic process|downregulation of penicillin biosynthesis|inhibition of penicillin synthesis|inhibition of penicillin formation|negative regulation of penicillin biosynthesis|down-regulation of penicillin biosynthesis|down-regulation of penicillin biosynthetic process|negative regulation of penicillin anabolism|down-regulation of penicillin anabolism|negative regulation of penicillin synthesis|down-regulation of penicillin synthesis|inhibition of penicillin biosynthetic process|negative regulation of penicillin formation|down-regulation of penicillin formation|downregulation of penicillin anabolism|inhibition of penicillin biosynthesis|down regulation of penicillin anabolism|downregulation of penicillin synthesis|downregulation of penicillin formation|down regulation of penicillin synthesis|down regulation of penicillin biosynthesis|down regulation of penicillin biosynthetic process http://purl.obolibrary.org/obo/GO_1900197 GO:1900199 biolink:BiologicalProcess positive regulation of protein export from nucleus during meiotic anaphase II Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II. go-plus.json positive regulation of protein export from nucleus involved in meiotic anaphase II http://purl.obolibrary.org/obo/GO_1900199 CHEBI:74917 biolink:ChemicalSubstance 1-acyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74917 chebi_ph7_3 CHEBI:74920 biolink:ChemicalSubstance 1-acyl-2-linoleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74920 chebi_ph7_3 CHEBI:74922 biolink:ChemicalSubstance 1-acyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74922 chebi_ph7_3 CHEBI:74925 biolink:ChemicalSubstance EC 3.4.23.46 (memapsin 2) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_74925 CHEBI:74924 biolink:ChemicalSubstance aclacinomycin N(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74924 CHEBI:74929 biolink:ChemicalSubstance aclacinomycin Y(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74929 CHEBI:74928 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74928 chebi_ph7_3 CHEBI:74930 biolink:ChemicalSubstance 1-oleoyl-2-myristoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74930 CHEBI:74931 biolink:ChemicalSubstance tetracenomycin F1(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74931 chebi_ph7_3 CHEBI:74934 biolink:ChemicalSubstance tetracenomycin D3(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74934 CHEBI:74933 biolink:ChemicalSubstance 1-(gamma-linolenoyl)-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74933 CHEBI:74936 biolink:ChemicalSubstance 1-(gamma-linolenoyl)-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74936 CHEBI:74938 biolink:ChemicalSubstance 1-arachidonoyl-sn-glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74938 chebi_ph7_3 CHEBI:74937 biolink:ChemicalSubstance 1-oleoyl-2-icosanoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74937 chebi_ph7_3 CHEBI:74939 biolink:ChemicalSubstance 1-icosanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74939 CHEBI:59399 biolink:ChemicalSubstance glutathione amide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59399 CHEBI:74941 biolink:ChemicalSubstance 1-arachidonoyl-2-oleoyl-sn-glycero-3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74941 chebi_ph7_3 CHEBI:74943 biolink:ChemicalSubstance 1-myristoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74943 CHEBI:74942 biolink:ChemicalSubstance 1-icosanoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74942 CHEBI:74945 biolink:ChemicalSubstance 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate(14-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74945 CHEBI:74946 biolink:ChemicalSubstance 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate(13-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74946 chebi_ph7_3 UBERON:0002714 biolink:AnatomicalEntity rubrospinal tract White matter tract arising in red nucleus and projecting to spinal cord ventral horn go-plus.json tractus rubrospinalis|Monakow's tract|rubrospinal tract (Monakow) http://purl.obolibrary.org/obo/UBERON_0002714 CHEBI:74949 biolink:ChemicalSubstance EC 3.1.27.3 (ribonuclease T1) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_74949 CHEBI:74948 biolink:ChemicalSubstance guanosine 2'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74948 CHEBI:60302 biolink:ChemicalSubstance L-thyroxine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60302 CHEBI:59386 biolink:ChemicalSubstance 2-O-(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_59386 CHEBI:60308 biolink:ChemicalSubstance 3,3',5-triiodo-L-thyroninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60308 UBERON:0002722 biolink:AnatomicalEntity trochlear nucleus Nucleus in the midbrain at the level of the inferior colliculus near the midline, containing the motor neurons giving rise to the trochlear nerve, innervating the contralateral superior oblique extraocular muscle of the eye (Brodal, Neurological Anatomy, 3rd ed, 1981, pg. 533). go-plus.json fourth cranial nerve nucleus|nucleus of trochlear nerve|nucleus nervi trochlearis|trochlear motor nucleus|nucleus nervi trochlearis|motor nucleus IV|trochlear IV nucleus|nIV http://purl.obolibrary.org/obo/UBERON_0002722 CHEBI:74951 biolink:ChemicalSubstance cysteamine S-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74951 UBERON:0002707 biolink:AnatomicalEntity corticospinal tract The corticospinal fibers that arise from the pyramidal cells within the cerebral cortex layer V of the precentral motor area, the premotor area and the postcentral gyrus, then descend into and through the medulla to form the lateral corticospinal tract and the anterior corticospinal tract. go-plus.json fibrae corticospinales|tractus pyramidalis|pyramid (Willis)|corticospinal fibers|tractus corticospinalis|tractus cortico-spinalis|pyramidal tract|fasciculus cerebro-spinalis|fasciculus pyramidalis http://purl.obolibrary.org/obo/UBERON_0002707 CHEBI:74956 biolink:ChemicalSubstance O(4)-phosphotyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74956 CHEBI:74955 biolink:ChemicalSubstance O(4)-phosphonatotyrosine(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74955 chebi_ph7_3 CHEBI:74958 biolink:ChemicalSubstance N-isovaleryl-L-homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_74958 chebi_ph7_3 UBERON:0002704 biolink:AnatomicalEntity metathalamus The metathalamus is a composite structure of the thalamus, consisting of the medial geniculate nucleus and the lateral geniculate nucleus. [WP,unvetted]. go-plus.json geniculate thalamic nuclear group (metathalamus)|MTh|geniculate group of dorsal thalamus|corpora geniculata|geniculate thalamic group|nuclei metathalami|geniculate group of the dorsal thalamus http://purl.obolibrary.org/obo/UBERON_0002704 CHEBI:74959 biolink:ChemicalSubstance O(4)-phospho-D-tyrosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74959 CHEBI:60311 biolink:ChemicalSubstance thyroid hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_60311 CHEBI:60312 biolink:ChemicalSubstance 2-amino-2-deoxy-D-galactopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_60312 CHEBI:60319 biolink:ChemicalSubstance 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60319 OBO:uberon/core#layer_part_of biolink:OntologyClass layer part of layer_part_of go-plus.json http://purl.obolibrary.org/obo/uberon/core#layer_part_of CHEBI:74950 biolink:ChemicalSubstance organic phosphorothioate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74950 CHEBI:74963 biolink:ChemicalSubstance 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74963 chebi_ph7_3 CHEBI:74965 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74965 chebi_ph7_3 CHEBI:74967 biolink:ChemicalSubstance 1-lauroyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74967 chebi_ph7_3 CHEBI:74966 biolink:ChemicalSubstance 1-lauroyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74966 chebi_ph7_3 CHEBI:74969 biolink:ChemicalSubstance mucilage go-plus.json http://purl.obolibrary.org/obo/CHEBI_74969 CHEBI:74968 biolink:ChemicalSubstance 1-icosanoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74968 chebi_ph7_3 CHEBI:35399 biolink:ChemicalSubstance D-tartrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35399 CHEBI:35398 biolink:ChemicalSubstance L-tartrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35398 CHEBI:142638 biolink:ChemicalSubstance nectriapyrones go-plus.json http://purl.obolibrary.org/obo/CHEBI_142638 CHEBI:59360 biolink:ChemicalSubstance hexacarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59360 CHEBI:60327 biolink:ChemicalSubstance ganglioside GM2 (18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60327 CHEBI:35391 biolink:ChemicalSubstance aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35391 chebi_ph7_3 CHEBI:35390 biolink:ChemicalSubstance galactarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35390 CHEBI:35392 biolink:ChemicalSubstance glucarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35392 CHEBI:74961 biolink:ChemicalSubstance raffinose family oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_74961 CHEBI:35397 biolink:ChemicalSubstance tartrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35397 CHEBI:74974 biolink:ChemicalSubstance N-(4-coumaroyl)-L-homoserine lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_74974 chebi_ph7_3 CHEBI:74975 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74975 chebi_ph7_3 CHEBI:74978 biolink:ChemicalSubstance ginsenoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_74978 CHEBI:74977 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74977 chebi_ph7_3 CHEBI:142622 biolink:ChemicalSubstance primary fatty alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_142622 chebi_ph7_3 CHEBI:142621 biolink:ChemicalSubstance medium-chain fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_142621 chebi_ph7_3 CHEBI:60331 biolink:ChemicalSubstance 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60331 chebi_ph7_3 CHEBI:60332 biolink:ChemicalSubstance alpha-D-mannose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60332 chebi_ph7_3 CHEBI:59354 biolink:ChemicalSubstance (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59354 CHEBI:59353 biolink:ChemicalSubstance (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59353 chebi_ph7_3 CHEBI:60334 biolink:ChemicalSubstance peptide anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60334 CHEBI:59352 biolink:ChemicalSubstance chromenemonocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59352 CHEBI:142626 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142626 chebi_ph7_3 CHEBI:59350 biolink:ChemicalSubstance 2-hydroxychromene-2-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59350 chebi_ph7_3 CHEBI:74970 biolink:ChemicalSubstance 1-icosanoyl-2-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74970 chebi_ph7_3 CHEBI:59359 biolink:ChemicalSubstance hexacarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59359 CHEBI:74972 biolink:ChemicalSubstance (11Z,14Z,17Z,20Z,23Z)-3-oxohexacosapentaenoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_74972 CHEBI:74971 biolink:ChemicalSubstance 1-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74971 chebi_ph7_3 CHEBI:59356 biolink:ChemicalSubstance 7-(3-methylbut-2-enyl)-L-tryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_59356 GO:0071242 biolink:BiologicalProcess cellular response to ammonium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. go-plus.json cellular response to ammonia http://purl.obolibrary.org/obo/GO_0071242 GO:0046286 biolink:BiologicalProcess flavonoid phytoalexin catabolic process The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection. go-plus.json flavonoid phytoalexin catabolism|flavonoid phytoalexin degradation|flavonoid phytoalexin breakdown http://purl.obolibrary.org/obo/GO_0046286 GO:0046285 biolink:BiologicalProcess flavonoid phytoalexin metabolic process The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection. go-plus.json flavonoid phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0046285 GO:0071241 biolink:BiologicalProcess cellular response to inorganic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071241 GO:0071240 biolink:BiologicalProcess cellular response to food Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat. go-plus.json http://purl.obolibrary.org/obo/GO_0071240 GO:0046284 biolink:BiologicalProcess anthocyanin-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins. go-plus.json anthocyanin degradation|anthocyanin catabolism|anthocyanin breakdown|anthocyanin catabolic process http://purl.obolibrary.org/obo/GO_0046284 GO:0046283 biolink:BiologicalProcess anthocyanin-containing compound metabolic process The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers. go-plus.json anthocyanin metabolic process|anthocyanin metabolism http://purl.obolibrary.org/obo/GO_0046283 GO:0046282 biolink:BiologicalProcess cinnamic acid ester catabolic process The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid. go-plus.json cinnamic acid ester catabolism|cinnamic acid ester degradation|cinnamic acid ester breakdown http://purl.obolibrary.org/obo/GO_0046282 GO:1900118 biolink:BiologicalProcess negative regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. go-plus.json downregulation of execution phase of apoptosis|down regulation of execution phase of apoptosis|inhibition of execution phase of apoptosis|down-regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900118 GO:1900117 biolink:BiologicalProcess regulation of execution phase of apoptosis Any process that modulates the frequency, rate or extent of execution phase of apoptosis. go-plus.json http://purl.obolibrary.org/obo/GO_1900117 GO:0046281 biolink:BiologicalProcess cinnamic acid catabolic process The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid. go-plus.json cinnamic acid catabolism|phenylacrylic acid catabolism|cinnamylic acid catabolic process|cinnamic acid degradation|cinnamic acid breakdown|cinnamylic acid catabolism|phenylacrylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046281 GO:0046280 biolink:BiologicalProcess chalcone catabolic process The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives. go-plus.json chalcone catabolism|chalcone degradation|chalcone breakdown http://purl.obolibrary.org/obo/GO_0046280 GO:1900119 biolink:BiologicalProcess positive regulation of execution phase of apoptosis Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. go-plus.json upregulation of execution phase of apoptosis|up-regulation of execution phase of apoptosis|activation of execution phase of apoptosis|up regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900119 GO:1900114 biolink:BiologicalProcess positive regulation of histone H3-K9 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation. go-plus.json upregulation of histone H3-K9 trimethylation|up-regulation of histone H3-K9 trimethylation|activation of histone H3-K9 trimethylation|up regulation of histone H3-K9 trimethylation http://purl.obolibrary.org/obo/GO_1900114 GO:1900113 biolink:BiologicalProcess negative regulation of histone H3-K9 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation. go-plus.json down regulation of histone H3-K9 trimethylation|inhibition of histone H3-K9 trimethylation|down-regulation of histone H3-K9 trimethylation|downregulation of histone H3-K9 trimethylation http://purl.obolibrary.org/obo/GO_1900113 GO:1900116 biolink:BiologicalProcess extracellular negative regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. go-plus.json inhibition of signal transduction in extracellular region|negative regulation of signalling pathway in extracellular region|negative regulation of signaling pathway in extracellular region|down regulation of signal transduction in extracellular region|extracellular inhibition of signaling pathway|downregulation of signal transduction in extracellular region|down-regulation of signal transduction in extracellular region http://purl.obolibrary.org/obo/GO_1900116 GO:1900115 biolink:BiologicalProcess extracellular regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. go-plus.json regulation of signaling pathway in extracellular region|regulation of signalling pathway in extracellular region http://purl.obolibrary.org/obo/GO_1900115 GO:1900110 biolink:BiologicalProcess negative regulation of histone H3-K9 dimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation. go-plus.json negative regulation of histone lysine H3 K9 dimethylation|down-regulation of histone lysine H3 K9 dimethylation|down-regulation of histone H3-K9 dimethylation|down regulation of histone H3 K9 dimethylation|downregulation of histone H3 K9 dimethylation|inhibition of histone H3-K9 dimethylation|downregulation of histone lysine H3 K9 dimethylation|down regulation of histone lysine H3 K9 dimethylation|negative regulation of histone H3 K9 dimethylation|down-regulation of histone H3 K9 dimethylation|inhibition of histone lysine H3 K9 dimethylation|down regulation of histone H3-K9 dimethylation|inhibition of histone H3 K9 dimethylation|downregulation of histone H3-K9 dimethylation http://purl.obolibrary.org/obo/GO_1900110 GO:0046289 biolink:BiologicalProcess isoflavonoid phytoalexin metabolic process The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection. go-plus.json isoflavonoid phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0046289 GO:0046288 biolink:BiologicalProcess isoflavonoid catabolic process The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids. go-plus.json isoflavonoid breakdown|isoflavonoid catabolism|isoflavonoid degradation http://purl.obolibrary.org/obo/GO_0046288 GO:1900112 biolink:BiologicalProcess regulation of histone H3-K9 trimethylation Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation. go-plus.json http://purl.obolibrary.org/obo/GO_1900112 GO:1900111 biolink:BiologicalProcess positive regulation of histone H3-K9 dimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation. go-plus.json upregulation of histone H3 K9 dimethylation|positive regulation of histone lysine H3 K9 dimethylation|up regulation of histone lysine H3 K9 dimethylation|up-regulation of histone H3-K9 dimethylation|up regulation of histone H3 K9 dimethylation|activation of histone H3 K9 dimethylation|positive regulation of histone H3 K9 dimethylation|upregulation of histone lysine H3 K9 dimethylation|upregulation of histone H3-K9 dimethylation|up-regulation of histone H3 K9 dimethylation|activation of histone lysine H3 K9 dimethylation|up-regulation of histone lysine H3 K9 dimethylation|up regulation of histone H3-K9 dimethylation|activation of histone H3-K9 dimethylation http://purl.obolibrary.org/obo/GO_1900111 GO:0046287 biolink:BiologicalProcess isoflavonoid metabolic process The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group. go-plus.json isoflavonoid metabolism http://purl.obolibrary.org/obo/GO_0046287 GO:0071249 biolink:BiologicalProcess cellular response to nitrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071249 GO:0071248 biolink:BiologicalProcess cellular response to metal ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. go-plus.json cellular response to heavy metal|cellular response to metal http://purl.obolibrary.org/obo/GO_0071248 GO:0071247 biolink:BiologicalProcess cellular response to chromate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071247 GO:0071246 biolink:BiologicalProcess cellular response to chlorate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071246 GO:0071245 biolink:BiologicalProcess cellular response to carbon monoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071245 GO:0071244 biolink:BiologicalProcess cellular response to carbon dioxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071244 GO:0071243 biolink:BiologicalProcess cellular response to arsenic-containing substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. go-plus.json cellular response to arsenic http://purl.obolibrary.org/obo/GO_0071243 GO:0046297 biolink:BiologicalProcess obsolete 2,4-dichlorobenzoate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). go-plus.json 2,4-dichlorobenzoate anabolism|2,4-dichlorobenzoate synthesis|2,4-dichlorobenzoate formation|2,4-dichlorobenzoate biosynthetic process|2,4-dichlorobenzoate biosynthesis http://purl.obolibrary.org/obo/GO_0046297 GO:0071231 biolink:BiologicalProcess cellular response to folic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus. go-plus.json response to vitamin B9|response to folate http://purl.obolibrary.org/obo/GO_0071231 GO:0071230 biolink:BiologicalProcess cellular response to amino acid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. go-plus.json cellular response to amino acid http://purl.obolibrary.org/obo/GO_0071230 GO:0046296 biolink:BiologicalProcess glycolate catabolic process The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid). go-plus.json glycolate degradation|glycolate catabolism|glycolate breakdown http://purl.obolibrary.org/obo/GO_0046296 GO:0046295 biolink:BiologicalProcess glycolate biosynthetic process The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid). go-plus.json glycolate synthesis|glycolate formation|glycolate biosynthesis|glycolate anabolism http://purl.obolibrary.org/obo/GO_0046295 GO:0046294 biolink:BiologicalProcess formaldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde. go-plus.json formaldehyde catabolism|methanal catabolism|formaldehyde degradation|formaldehyde breakdown|methanal catabolic process http://purl.obolibrary.org/obo/GO_0046294 GO:1900129 biolink:BiologicalProcess positive regulation of G-protein activated inward rectifier potassium channel activity Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity. go-plus.json upregulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G-protein activated inward rectifier potassium channel activity|up-regulation of G protein activated inward rectifier potassium channel activity|activation of G-protein activated inward rectifier potassium channel activity|upregulation of G-protein-enhanced inward rectifier potassium channel activity|positive regulation of G-protein enhanced inward rectifier potassium channel activity|upregulation of G-protein-activated inward rectifier potassium channel activity|up-regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G-protein enhanced inward rectifier potassium channel activity|activation of G protein enhanced inward rectifier potassium channel activity|upregulation of G protein activated inward rectifier potassium channel activity|up-regulation of G-protein-enhanced inward rectifier potassium channel activity|activation of G-protein-enhanced inward rectifier potassium channel activity|up regulation of G-protein-activated inward rectifier potassium channel activity|up-regulation of G-protein activated inward rectifier potassium channel activity|activation of G-protein-activated inward rectifier potassium channel activity|upregulation of G-protein enhanced inward rectifier potassium channel activity|positive regulation of G-protein-activated inward rectifier potassium channel activity|positive regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G protein activated inward rectifier potassium channel activity|activation of G protein activated inward rectifier potassium channel activity|positive regulation of G protein activated inward rectifier potassium channel activity|upregulation of G-protein activated inward rectifier potassium channel activity|positive regulation of G-protein-enhanced inward rectifier potassium channel activity|up regulation of G-protein-enhanced inward rectifier potassium channel activity|up-regulation of G-protein enhanced inward rectifier potassium channel activity|activation of G-protein enhanced inward rectifier potassium channel activity|up-regulation of G-protein-activated inward rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_1900129 GO:0046293 biolink:BiologicalProcess formaldehyde biosynthetic process The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde. go-plus.json formaldehyde anabolism|formaldehyde synthesis|formaldehyde formation|formaldehyde biosynthesis|methanal biosynthetic process|methanal biosynthesis http://purl.obolibrary.org/obo/GO_0046293 CHEBI:25901 biolink:ChemicalSubstance pentose go-plus.json http://purl.obolibrary.org/obo/CHEBI_25901 GO:1900128 biolink:BiologicalProcess regulation of G-protein activated inward rectifier potassium channel activity Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity. go-plus.json regulation of G-protein-enhanced inward rectifier potassium channel activity|regulation of G-protein-activated inward rectifier potassium channel activity|regulation of G-protein enhanced inward rectifier potassium channel activity|regulation of G protein activated inward rectifier potassium channel activity|regulation of G protein enhanced inward rectifier potassium channel activity http://purl.obolibrary.org/obo/GO_1900128 GO:0046292 biolink:BiologicalProcess formaldehyde metabolic process The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent. go-plus.json formaldehyde metabolism|methanal metabolic process|methanal metabolism http://purl.obolibrary.org/obo/GO_0046292 CHEBI:25900 biolink:ChemicalSubstance aldopentose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25900 GO:0046291 biolink:BiologicalProcess obsolete 6-hydroxycineole biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2. go-plus.json 6-endo-hydroxycineole biosynthesis|6-endo-hydroxycineole biosynthetic process|6-hydroxycineole anabolism|6-hydroxycineole synthesis|6-hydroxycineole formation|hydroxycineol biosynthesis|hydroxycineol biosynthetic process|6-hydroxycineole biosynthesis|6-hydroxycineole biosynthetic process http://purl.obolibrary.org/obo/GO_0046291 GO:0046290 biolink:BiologicalProcess isoflavonoid phytoalexin catabolic process The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection. go-plus.json isoflavonoid phytoalexin degradation|isoflavonoid phytoalexin breakdown|isoflavonoid phytoalexin catabolism http://purl.obolibrary.org/obo/GO_0046290 GO:1900125 biolink:BiologicalProcess regulation of hyaluronan biosynthetic process Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. go-plus.json regulation of hyaluronan biosynthesis|regulation of hyaluronan anabolism|regulation of hyaluronan synthesis|regulation of hyaluronan formation http://purl.obolibrary.org/obo/GO_1900125 GO:1900124 biolink:BiologicalProcess negative regulation of nodal receptor complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly. go-plus.json inhibition of ActRIIB.ALK4.EGF-CFC complex formation|down regulation of nodal receptor complex assembly|downregulation of nodal receptor complex assembly|down-regulation of nodal receptor complex formation|negative regulation of nodal receptor complex formation|down-regulation of nodal receptor complex assembly|down-regulation of ActRIIB.ALK4.EGF-CFC complex formation|negative regulation of ActRIIB.ALK4.EGF-CFC complex formation|downregulation of nodal receptor complex formation|inhibition of nodal receptor complex assembly|down regulation of nodal receptor complex formation|downregulation of ActRIIB.ALK4.EGF-CFC complex formation|inhibition of nodal receptor complex formation|down regulation of ActRIIB.ALK4.EGF-CFC complex formation http://purl.obolibrary.org/obo/GO_1900124 GO:1900127 biolink:BiologicalProcess positive regulation of hyaluronan biosynthetic process Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. go-plus.json upregulation of hyaluronan biosynthesis|upregulation of hyaluronan biosynthetic process|activation of hyaluronan synthesis|positive regulation of hyaluronan anabolism|activation of hyaluronan formation|up regulation of hyaluronan anabolism|positive regulation of hyaluronan synthesis|up regulation of hyaluronan synthesis|positive regulation of hyaluronan formation|up regulation of hyaluronan biosynthetic process|up regulation of hyaluronan biosynthesis|up regulation of hyaluronan formation|positive regulation of hyaluronan biosynthesis|activation of hyaluronan biosynthetic process|upregulation of hyaluronan anabolism|activation of hyaluronan biosynthesis|upregulation of hyaluronan synthesis|upregulation of hyaluronan formation|up-regulation of hyaluronan anabolism|up-regulation of hyaluronan biosynthesis|up-regulation of hyaluronan biosynthetic process|up-regulation of hyaluronan synthesis|activation of hyaluronan anabolism|up-regulation of hyaluronan formation http://purl.obolibrary.org/obo/GO_1900127 GO:1900126 biolink:BiologicalProcess negative regulation of hyaluronan biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. go-plus.json down-regulation of hyaluronan synthesis|negative regulation of hyaluronan synthesis|down regulation of hyaluronan biosynthetic process|down regulation of hyaluronan biosynthesis|negative regulation of hyaluronan formation|down-regulation of hyaluronan formation|downregulation of hyaluronan biosynthesis|downregulation of hyaluronan biosynthetic process|downregulation of hyaluronan anabolism|downregulation of hyaluronan synthesis|down regulation of hyaluronan anabolism|downregulation of hyaluronan formation|down regulation of hyaluronan synthesis|down-regulation of hyaluronan biosynthetic process|down-regulation of hyaluronan biosynthesis|negative regulation of hyaluronan biosynthesis|inhibition of hyaluronan anabolism|down regulation of hyaluronan formation|inhibition of hyaluronan synthesis|inhibition of hyaluronan biosynthetic process|inhibition of hyaluronan formation|inhibition of hyaluronan biosynthesis|negative regulation of hyaluronan anabolism|down-regulation of hyaluronan anabolism http://purl.obolibrary.org/obo/GO_1900126 GO:1900121 biolink:BiologicalProcess negative regulation of receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. go-plus.json downregulation of receptor binding|down regulation of receptor binding|inhibition of receptor binding|inhibition of receptor ligand|down regulation of receptor-associated protein activity|down-regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900121 GO:1900120 biolink:BiologicalProcess regulation of receptor binding Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor. go-plus.json regulation of receptor ligand http://purl.obolibrary.org/obo/GO_1900120 GO:0046299 biolink:BiologicalProcess obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. go-plus.json 2,4-dichlorophenoxyacetic acid anabolism|2,4-dichlorophenoxyacetic acid synthesis|2,4-dichlorophenoxyacetic acid formation|2,4-dichlorophenoxyacetic acid biosynthetic process|2,4-dichlorophenoxyacetic acid biosynthesis http://purl.obolibrary.org/obo/GO_0046299 GO:1900123 biolink:BiologicalProcess regulation of nodal receptor complex assembly Any process that modulates the frequency, rate or extent of nodal receptor complex assembly. go-plus.json regulation of nodal receptor complex formation|regulation of ActRIIB.ALK4.EGF-CFC complex formation http://purl.obolibrary.org/obo/GO_1900123 GO:0046298 biolink:BiologicalProcess 2,4-dichlorobenzoate catabolic process The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). go-plus.json 2,4-dichlorobenzoate degradation|2,4-dichlorobenzoate breakdown|2,4-dichlorobenzoate catabolism http://purl.obolibrary.org/obo/GO_0046298 GO:1900122 biolink:BiologicalProcess positive regulation of receptor binding Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor. go-plus.json upregulation of receptor binding|activation of receptor binding|up regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900122 GO:1900130 biolink:BiologicalProcess regulation of lipid binding Any process that modulates the frequency, rate or extent of lipid binding. go-plus.json http://purl.obolibrary.org/obo/GO_1900130 GO:0071239 biolink:BiologicalProcess cellular response to streptomycin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. go-plus.json http://purl.obolibrary.org/obo/GO_0071239 CHEBI:25905 biolink:ChemicalSubstance peptide hormone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25905 GO:0071238 biolink:BiologicalProcess cellular response to brefeldin A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071238 CHEBI:25903 biolink:ChemicalSubstance peptide antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_25903 GO:0071237 biolink:BiologicalProcess cellular response to bacteriocin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation. go-plus.json http://purl.obolibrary.org/obo/GO_0071237 GO:0071236 biolink:BiologicalProcess cellular response to antibiotic Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. go-plus.json http://purl.obolibrary.org/obo/GO_0071236 GO:0071235 biolink:BiologicalProcess cellular response to proline Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071235 CHEBI:25909 biolink:ChemicalSubstance peptidyl-1-thioglycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25909 GO:0071234 biolink:BiologicalProcess cellular response to phenylalanine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071234 GO:0071233 biolink:BiologicalProcess cellular response to leucine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071233 CHEBI:25907 biolink:ChemicalSubstance peptidyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_25907 GO:0071232 biolink:BiologicalProcess cellular response to histidine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071232 GO:0071264 biolink:BiologicalProcess positive regulation of translational initiation in response to starvation Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment. go-plus.json up regulation of translation initiation in response to starvation|positive regulation of translational initiation in response to nutrient starvation|upregulation of translation initiation in response to starvation|stimulation of translation initiation in response to starvation|up-regulation of translation initiation in response to starvation|activation of translation initiation in response to starvation http://purl.obolibrary.org/obo/GO_0071264 GO:0071263 biolink:BiologicalProcess negative regulation of translational initiation in response to starvation Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment. go-plus.json downregulation of translation initiation in response to starvation|down regulation of translation initiation in response to starvation|inhibition of translation initiation in response to starvation|negative regulation of translational initiation in response to nutrient starvation|down-regulation of translation initiation in response to starvation http://purl.obolibrary.org/obo/GO_0071263 GO:0071262 biolink:BiologicalProcess regulation of translational initiation in response to starvation Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment. go-plus.json regulation of translational initiation in response to nutrient starvation http://purl.obolibrary.org/obo/GO_0071262 GO:0071261 biolink:CellularComponent Ssh1 translocon complex A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences. go-plus.json Ssh1p-Sss1p-Sbh2p complex http://purl.obolibrary.org/obo/GO_0071261 GO:0071260 biolink:BiologicalProcess cellular response to mechanical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. go-plus.json cellular mechanical stimulus response http://purl.obolibrary.org/obo/GO_0071260 GO:1900139 biolink:BiologicalProcess negative regulation of arachidonic acid secretion Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion. go-plus.json downregulation of arachidonic acid secretion|down regulation of arachidonic acid secretion|inhibition of arachidonic acid secretion|down-regulation of arachidonic acid secretion http://purl.obolibrary.org/obo/GO_1900139 GO:1900136 biolink:BiologicalProcess regulation of chemokine activity Any process that modulates the frequency, rate or extent of chemokine activity. go-plus.json http://purl.obolibrary.org/obo/GO_1900136 GO:1900135 biolink:BiologicalProcess positive regulation of renin secretion into blood stream Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream. go-plus.json up-regulation of renin release into blood stream|up regulation of renin secretion into blood stream|activation of renin secretion into blood stream|upregulation of renin release into blood stream|up-regulation of renin secretion into blood stream|up regulation of renin release into blood stream|activation of renin release into blood stream|positive regulation of renin release into blood stream|upregulation of renin secretion into blood stream http://purl.obolibrary.org/obo/GO_1900135 GO:1900138 biolink:BiologicalProcess negative regulation of phospholipase A2 activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity. go-plus.json down regulation of phospholipase A2 activity|downregulation of lecithinase A activity|down regulation of phospholipase A|down regulation of cytosolic phospholipase A2 activity|downregulation of phospholipase A2 activity|down regulation of lecithinase A activity|inhibition of phosphatidase activity|downregulation of phospholipase A|downregulation of secreted phospholipase A2 activity|inhibition of lecithinase A activity|downregulation of cytosolic phospholipase A2 activity|negative regulation of phosphatidolipase activity|down-regulation of phosphatidolipase activity|down regulation of secreted phospholipase A2 activity|negative regulation of phosphatidylcholine 2-acylhydrolase activity|down-regulation of phosphatidylcholine 2-acylhydrolase activity|down-regulation of phospholipase A2 activity|negative regulation of cytosolic phospholipase A2 activity|down-regulation of phospholipase A|down-regulation of cytosolic phospholipase A2 activity|negative regulation of phospholipase A|down-regulation of phosphatidase activity|negative regulation of phosphatidase activity|inhibition of secreted phospholipase A2 activity|downregulation of phosphatidolipase activity|inhibition of phospholipase A2 activity|downregulation of phosphatidylcholine 2-acylhydrolase activity|down regulation of phosphatidolipase activity|down-regulation of lecithinase A activity|inhibition of phosphatidolipase activity|negative regulation of lecithinase A activity|down regulation of phosphatidylcholine 2-acylhydrolase activity|downregulation of phosphatidase activity|inhibition of phosphatidylcholine 2-acylhydrolase activity|inhibition of phospholipase A|inhibition of cytosolic phospholipase A2 activity|negative regulation of secreted phospholipase A2 activity|down-regulation of secreted phospholipase A2 activity|down regulation of phosphatidase activity http://purl.obolibrary.org/obo/GO_1900138 GO:1900137 biolink:BiologicalProcess negative regulation of chemokine activity Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity. go-plus.json down regulation of chemokine activity|inhibition of chemokine activity|down-regulation of chemokine activity|downregulation of chemokine activity http://purl.obolibrary.org/obo/GO_1900137 GO:1900132 biolink:BiologicalProcess positive regulation of lipid binding Any process that activates or increases the frequency, rate or extent of lipid binding. go-plus.json upregulation of lipid binding|up regulation of lipid binding|activation of lipid binding|up-regulation of lipid binding http://purl.obolibrary.org/obo/GO_1900132 GO:1900131 biolink:BiologicalProcess negative regulation of lipid binding Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. go-plus.json down regulation of lipid binding|downregulation of lipid binding|down-regulation of lipid binding|inhibition of lipid binding http://purl.obolibrary.org/obo/GO_1900131 GO:1900134 biolink:BiologicalProcess negative regulation of renin secretion into blood stream Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream. go-plus.json down-regulation of renin secretion into blood stream|down regulation of renin release into blood stream|inhibition of renin secretion into blood stream|downregulation of renin release into blood stream|down-regulation of renin release into blood stream|negative regulation of renin release into blood stream|down regulation of renin secretion into blood stream|downregulation of renin secretion into blood stream|inhibition of renin release into blood stream http://purl.obolibrary.org/obo/GO_1900134 GO:1900133 biolink:BiologicalProcess regulation of renin secretion into blood stream Any process that modulates the frequency, rate or extent of renin secretion into blood stream. go-plus.json regulation of renin release into blood stream http://purl.obolibrary.org/obo/GO_1900133 GO:1900141 biolink:BiologicalProcess regulation of oligodendrocyte apoptotic process Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process. go-plus.json regulation of oligodendrocyte apoptosis http://purl.obolibrary.org/obo/GO_1900141 GO:1900140 biolink:BiologicalProcess regulation of seedling development Any process that modulates the frequency, rate or extent of seedling development. go-plus.json http://purl.obolibrary.org/obo/GO_1900140 GO:0071269 biolink:BiologicalProcess L-homocysteine biosynthetic process The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid. go-plus.json L-homocysteine anabolism|L-homocysteine biosynthesis|L-homocysteine synthesis|L-homocysteine formation http://purl.obolibrary.org/obo/GO_0071269 GO:0071268 biolink:BiologicalProcess homocysteine biosynthetic process The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid. go-plus.json homocysteine anabolism|homocysteine biosynthesis|homocysteine synthesis|homocysteine formation http://purl.obolibrary.org/obo/GO_0071268 GO:0071267 biolink:BiologicalProcess L-methionine salvage Any process that generates L-methionine from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0071267 GO:0071266 biolink:BiologicalProcess 'de novo' L-methionine biosynthetic process The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components. go-plus.json 'de novo' L-methionine anabolism|'de novo' L-methionine synthesis|'de novo' L-methionine formation|'de novo' L-methionine biosynthesis http://purl.obolibrary.org/obo/GO_0071266 GO:0071265 biolink:BiologicalProcess L-methionine biosynthetic process The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid. go-plus.json L-methionine formation|L-methionine biosynthesis|L-methionine anabolism|L-methionine synthesis http://purl.obolibrary.org/obo/GO_0071265 GO:0071253 biolink:MolecularActivity connexin binding Binding to a connexin, any of a group of related proteins that assemble to form gap junctions. go-plus.json http://purl.obolibrary.org/obo/GO_0071253 GO:0071252 biolink:BiologicalProcess cellular response to sulfur dioxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071252 GO:0071251 biolink:BiologicalProcess cellular response to silicon dioxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus. go-plus.json cellular response to silox|cellular response to silica http://purl.obolibrary.org/obo/GO_0071251 GO:0071250 biolink:BiologicalProcess cellular response to nitrite Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071250 GO:1900147 biolink:BiologicalProcess regulation of Schwann cell migration Any process that modulates the frequency, rate or extent of Schwann cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_1900147 GO:1900146 biolink:BiologicalProcess negative regulation of nodal signaling pathway involved in determination of left/right asymmetry Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry. go-plus.json down-regulation of nodal signaling pathway involved in determination of left/right asymmetry|inhibition of nodal signaling pathway involved in determination of left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of left/right asymmetry|down regulation of nodal signaling pathway involved in determination of left/right asymmetry|downregulation of nodal signaling pathway involved in determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_1900146 GO:1900149 biolink:BiologicalProcess positive regulation of Schwann cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell migration. go-plus.json up-regulation of Schwann cell migration|activation of Schwann cell migration|up regulation of Schwann cell migration|upregulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1900149 GO:1900148 biolink:BiologicalProcess negative regulation of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. go-plus.json down-regulation of Schwann cell migration|downregulation of Schwann cell migration|down regulation of Schwann cell migration|inhibition of Schwann cell migration http://purl.obolibrary.org/obo/GO_1900148 GO:1900143 biolink:BiologicalProcess positive regulation of oligodendrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process. go-plus.json upregulation of oligodendrocyte apoptotic process|up regulation of oligodendrocyte apoptosis|positive regulation of oligodendrocyte apoptosis|up regulation of oligodendrocyte apoptotic process|activation of oligodendrocyte apoptosis|activation of oligodendrocyte apoptotic process|up-regulation of oligodendrocyte apoptosis|up-regulation of oligodendrocyte apoptotic process|upregulation of oligodendrocyte apoptosis http://purl.obolibrary.org/obo/GO_1900143 GO:1900142 biolink:BiologicalProcess negative regulation of oligodendrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process. go-plus.json downregulation of oligodendrocyte apoptosis|down regulation of oligodendrocyte apoptotic process|downregulation of oligodendrocyte apoptotic process|negative regulation of oligodendrocyte apoptosis|down-regulation of oligodendrocyte apoptosis|down-regulation of oligodendrocyte apoptotic process|inhibition of oligodendrocyte apoptosis|inhibition of oligodendrocyte apoptotic process|down regulation of oligodendrocyte apoptosis http://purl.obolibrary.org/obo/GO_1900142 GO:1900145 biolink:BiologicalProcess regulation of nodal signaling pathway involved in determination of left/right asymmetry Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry. go-plus.json regulation of nodal signalling pathway involved in determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_1900145 GO:1900144 biolink:BiologicalProcess positive regulation of BMP secretion Any process that activates or increases the frequency, rate or extent of BMP secretion. go-plus.json activation of bone morphogenetic protein secretion|upregulation of BMP protein secretion|upregulation of BMP secretion|positive regulation of bone morphogenetic protein secretion|up regulation of bone morphogenetic protein secretion|up regulation of BMP protein secretion|positive regulation of BMP protein secretion|activation of BMP protein secretion|up regulation of BMP secretion|activation of BMP secretion|upregulation of bone morphogenetic protein secretion|up-regulation of BMP protein secretion|up-regulation of BMP secretion|up-regulation of bone morphogenetic protein secretion http://purl.obolibrary.org/obo/GO_1900144 GO:1900150 biolink:BiologicalProcess regulation of defense response to fungus Any process that modulates the frequency, rate or extent of defense response to fungus. go-plus.json regulation of response to pathogenic fungus (incompatible interaction)|regulation of defense response to fungi, incompatible interaction|regulation of defence response to fungi|regulation of defense response to fungus, incompatible interaction|regulation of resistance response to pathogenic fungi|regulation of defence response to fungus|regulation of defense response to fungi|regulation of resistance response to pathogenic fungus http://purl.obolibrary.org/obo/GO_1900150 GO:1900152 biolink:BiologicalProcess negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. go-plus.json down-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down-regulation of mRNA catabolic process, deadenylation-dependent|down-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|downregulation of deadenylation-dependent mRNA decay|negative regulation of mRNA catabolic process, deadenylation-dependent|downregulation of mRNA breakdown, deadenylation-dependent decay|downregulation of mRNA catabolism, deadenylylation-dependent|down regulation of mRNA degradation, deadenylation-dependent decay|down regulation of deadenylation-dependent mRNA decay|inhibition of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down-regulation of mRNA catabolism, deadenylation-dependent|negative regulation of mRNA catabolism, deadenylation-dependent|down regulation of mRNA catabolism, deadenylylation-dependent|downregulation of mRNA degradation, deadenylation-dependent decay|down regulation of mRNA catabolic process, deadenylylation-dependent|inhibition of deadenylation-dependent mRNA decay|inhibition of mRNA catabolic process, deadenylation-dependent|inhibition of nuclear mRNA catabolic process, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylylation-dependent|downregulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA breakdown, deadenylation-dependent decay|negative regulation of mRNA breakdown, deadenylation-dependent decay|down-regulation of mRNA degradation, deadenylation-dependent decay|negative regulation of mRNA degradation, deadenylation-dependent decay|downregulation of mRNA catabolism, deadenylation-dependent|inhibition of mRNA breakdown, deadenylation-dependent decay|down regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|down regulation of mRNA catabolic process, deadenylation-dependent|down regulation of mRNA catabolism, deadenylation-dependent|negative regulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA catabolic process, deadenylylation-dependent|downregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylation-dependent|inhibition of mRNA degradation, deadenylation-dependent decay|down-regulation of deadenylation-dependent mRNA decay|negative regulation of deadenylation-dependent mRNA decay|downregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|downregulation of mRNA catabolic process, deadenylation-dependent|down-regulation of mRNA catabolism, deadenylylation-dependent|negative regulation of mRNA catabolism, deadenylylation-dependent|inhibition of mRNA catabolic process, deadenylylation-dependent|down regulation of mRNA breakdown, deadenylation-dependent decay http://purl.obolibrary.org/obo/GO_1900152 GO:1900151 biolink:BiologicalProcess regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. go-plus.json regulation of mRNA breakdown, deadenylation-dependent decay|regulation of deadenylation-dependent mRNA decay|regulation of mRNA catabolism, deadenylylation-dependent|regulation of mRNA degradation, deadenylation-dependent decay|regulation of mRNA catabolic process, deadenylylation-dependent|regulation of mRNA catabolism, deadenylation-dependent|regulation of mRNA catabolic process, deadenylation-dependent|regulation of nuclear mRNA catabolic process, deadenylation-dependent decay http://purl.obolibrary.org/obo/GO_1900151 GO:0071259 biolink:BiologicalProcess cellular response to magnetism Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus. go-plus.json cellular response to magnetic stimulus http://purl.obolibrary.org/obo/GO_0071259 GO:0071258 biolink:BiologicalProcess cellular response to gravity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. go-plus.json cellular response to gravitational stimulus http://purl.obolibrary.org/obo/GO_0071258 GO:0071257 biolink:BiologicalProcess cellular response to electrical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. go-plus.json cellular response to electricity http://purl.obolibrary.org/obo/GO_0071257 GO:0071256 biolink:CellularComponent translocon complex A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins. go-plus.json Sec complex-associated translocon complex http://purl.obolibrary.org/obo/GO_0071256 goslim_pir GO:0071255 biolink:BiologicalProcess Cvt vesicle assembly A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI). go-plus.json Cvt vesicle formation|cytoplasm to vacuole targeting vesicle assembly|cytoplasm-to-vacuole targetin vesicle assembly|Cvt vesicle biosynthesis http://purl.obolibrary.org/obo/GO_0071255 GO:0071254 biolink:CellularComponent cytoplasmic U snRNP body A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies. go-plus.json U-body|U body http://purl.obolibrary.org/obo/GO_0071254 GO:0071286 biolink:BiologicalProcess cellular response to magnesium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071286 GO:0071285 biolink:BiologicalProcess cellular response to lithium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071285 GO:0071284 biolink:BiologicalProcess cellular response to lead ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071284 GO:0071283 biolink:BiologicalProcess cellular response to iron(III) ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus. go-plus.json cellular response to iron(III) http://purl.obolibrary.org/obo/GO_0071283 GO:0071282 biolink:BiologicalProcess cellular response to iron(II) ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus. go-plus.json cellular response to iron(II) http://purl.obolibrary.org/obo/GO_0071282 GO:0071281 biolink:BiologicalProcess cellular response to iron ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. go-plus.json cellular response to iron http://purl.obolibrary.org/obo/GO_0071281 GO:0071280 biolink:BiologicalProcess cellular response to copper ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus. go-plus.json cellular response to copper http://purl.obolibrary.org/obo/GO_0071280 GO:1900158 biolink:BiologicalProcess negative regulation of bone mineralization involved in bone maturation Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. go-plus.json inhibition of bone mineralization involved in bone maturation|down regulation of bone mineralization involved in bone maturation|downregulation of bone mineralization involved in bone maturation|down-regulation of bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_1900158 GO:1900157 biolink:BiologicalProcess regulation of bone mineralization involved in bone maturation Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation. go-plus.json http://purl.obolibrary.org/obo/GO_1900157 GO:1900159 biolink:BiologicalProcess positive regulation of bone mineralization involved in bone maturation Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation. go-plus.json up-regulation of bone mineralization involved in bone maturation|upregulation of bone mineralization involved in bone maturation|up regulation of bone mineralization involved in bone maturation|activation of bone mineralization involved in bone maturation http://purl.obolibrary.org/obo/GO_1900159 GO:1900154 biolink:BiologicalProcess regulation of bone trabecula formation Any process that modulates the frequency, rate or extent of bone trabecula formation. go-plus.json regulation of skeletal trabecula biogenesis|regulation of bone trabeculation|regulation of bone trabecula biogenesis|regulation of skeletal trabeculation|regulation of skeletal trabecula formation http://purl.obolibrary.org/obo/GO_1900154 GO:1900153 biolink:BiologicalProcess positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. go-plus.json up regulation of deadenylation-dependent mRNA decay|positive regulation of mRNA catabolism, deadenylylation-dependent|upregulation of mRNA degradation, deadenylation-dependent decay|up regulation of mRNA catabolism, deadenylylation-dependent|up-regulation of mRNA catabolism, deadenylation-dependent|activation of mRNA catabolism, deadenylation-dependent|upregulation of mRNA catabolic process, deadenylylation-dependent|up regulation of mRNA breakdown, deadenylation-dependent decay|up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|positive regulation of mRNA breakdown, deadenylation-dependent decay|activation of mRNA breakdown, deadenylation-dependent decay|up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|upregulation of deadenylation-dependent mRNA decay|up-regulation of mRNA catabolic process, deadenylation-dependent|upregulation of mRNA catabolism, deadenylylation-dependent|up regulation of mRNA degradation, deadenylation-dependent decay|positive regulation of mRNA catabolism, deadenylation-dependent|positive regulation of mRNA degradation, deadenylation-dependent decay|activation of mRNA degradation, deadenylation-dependent decay|up regulation of mRNA catabolism, deadenylation-dependent|up regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylylation-dependent|positive regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of mRNA catabolic process, deadenylation-dependent|upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of deadenylation-dependent mRNA decay|activation of deadenylation-dependent mRNA decay|up-regulation of mRNA breakdown, deadenylation-dependent decay|up-regulation of mRNA catabolism, deadenylylation-dependent|activation of mRNA catabolism, deadenylylation-dependent|upregulation of mRNA catabolism, deadenylation-dependent|up-regulation of mRNA degradation, deadenylation-dependent decay|up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|up regulation of mRNA catabolic process, deadenylation-dependent|activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of mRNA breakdown, deadenylation-dependent decay|positive regulation of deadenylation-dependent mRNA decay|positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylation-dependent|positive regulation of mRNA catabolic process, deadenylation-dependent|activation of nuclear mRNA catabolic process, deadenylation-dependent decay http://purl.obolibrary.org/obo/GO_1900153 GO:1900156 biolink:BiologicalProcess positive regulation of bone trabecula formation Any process that activates or increases the frequency, rate or extent of bone trabecula formation. go-plus.json up-regulation of skeletal trabeculation|positive regulation of bone trabeculation|activation of skeletal trabeculation|up regulation of bone trabeculation|up regulation of skeletal trabecula biogenesis|upregulation of bone trabecula biogenesis|up-regulation of skeletal trabecula formation|positive regulation of skeletal trabecula biogenesis|activation of skeletal trabecula formation|up regulation of bone trabecula formation|activation of skeletal trabecula biogenesis|positive regulation of skeletal trabeculation|upregulation of bone trabeculation|up regulation of skeletal trabeculation|up regulation of bone trabecula biogenesis|positive regulation of skeletal trabecula formation|up-regulation of skeletal trabecula biogenesis|upregulation of bone trabecula formation|positive regulation of bone trabecula biogenesis|up regulation of skeletal trabecula formation|activation of bone trabecula biogenesis|up-regulation of bone trabeculation|activation of bone trabeculation|upregulation of skeletal trabeculation|up-regulation of bone trabecula formation|upregulation of skeletal trabecula biogenesis|activation of bone trabecula formation|upregulation of skeletal trabecula formation|up-regulation of bone trabecula biogenesis http://purl.obolibrary.org/obo/GO_1900156 GO:1900155 biolink:BiologicalProcess negative regulation of bone trabecula formation Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation. go-plus.json down regulation of skeletal trabecula biogenesis|negative regulation of bone trabeculation|down-regulation of bone trabeculation|down-regulation of bone trabecula formation|inhibition of bone trabecula biogenesis|downregulation of skeletal trabecula biogenesis|downregulation of bone trabeculation|down regulation of bone trabecula biogenesis|down-regulation of skeletal trabeculation|negative regulation of skeletal trabeculation|negative regulation of skeletal trabecula biogenesis|downregulation of bone trabecula formation|down-regulation of skeletal trabecula biogenesis|down regulation of bone trabeculation|downregulation of bone trabecula biogenesis|negative regulation of skeletal trabecula formation|inhibition of bone trabeculation|down-regulation of skeletal trabecula formation|down regulation of bone trabecula formation|inhibition of bone trabecula formation|downregulation of skeletal trabeculation|down-regulation of bone trabecula biogenesis|negative regulation of bone trabecula biogenesis|downregulation of skeletal trabecula formation|down regulation of skeletal trabeculation|inhibition of skeletal trabecula biogenesis|inhibition of skeletal trabeculation|down regulation of skeletal trabecula formation|inhibition of skeletal trabecula formation http://purl.obolibrary.org/obo/GO_1900155 GO:1900161 biolink:BiologicalProcess regulation of phospholipid scramblase activity Any process that modulates the frequency, rate or extent of phospholipid scramblase activity. go-plus.json http://purl.obolibrary.org/obo/GO_1900161 GO:1900160 biolink:BiologicalProcess plastid DNA packaging Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure. go-plus.json DNA organization in plastid|DNA organisation in plastid|plastidial DNA packaging http://purl.obolibrary.org/obo/GO_1900160 GO:1900163 biolink:BiologicalProcess positive regulation of phospholipid scramblase activity Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity. go-plus.json up-regulation of phospholipid scramblase activity|activation of phospholipid scramblase activity|up regulation of phospholipid scramblase activity|upregulation of phospholipid scramblase activity http://purl.obolibrary.org/obo/GO_1900163 GO:1900162 biolink:BiologicalProcess negative regulation of phospholipid scramblase activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity. go-plus.json down-regulation of phospholipid scramblase activity|downregulation of phospholipid scramblase activity|down regulation of phospholipid scramblase activity|inhibition of phospholipid scramblase activity http://purl.obolibrary.org/obo/GO_1900162 GO:0071289 biolink:BiologicalProcess cellular response to nickel ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus. go-plus.json cellular response to nickel http://purl.obolibrary.org/obo/GO_0071289 GO:0071288 biolink:BiologicalProcess cellular response to mercury ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus. go-plus.json cellular response to mercuric ion|cellular response to mercury http://purl.obolibrary.org/obo/GO_0071288 GO:0071287 biolink:BiologicalProcess cellular response to manganese ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. go-plus.json cellular response to manganese http://purl.obolibrary.org/obo/GO_0071287 GO:0071275 biolink:BiologicalProcess cellular response to aluminum ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus. go-plus.json cellular response to aluminium ion|cellular response to aluminum http://purl.obolibrary.org/obo/GO_0071275 GO:0071274 biolink:BiologicalProcess isoquinoline alkaloid catabolic process The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin. go-plus.json isoquinoline alkaloid catabolism|ipecac alkaloid catabolism|isoquinoline alkaloid degradation|isoquinoline alkaloid breakdown http://purl.obolibrary.org/obo/GO_0071274 GO:0071273 biolink:BiologicalProcess morphine catabolic process The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. UniPathway:Q02198 go-plus.json morphine degradation|morphine breakdown|morphine catabolism http://purl.obolibrary.org/obo/GO_0071273 OBO:GOCHE_38157 biolink:OntologyClass substance with iron chelator role go-plus.json http://purl.obolibrary.org/obo/GOCHE_38157 3_STAR GO:0071272 biolink:BiologicalProcess morphine metabolic process The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. Wikipedia:Morphine go-plus.json morphine metabolism http://purl.obolibrary.org/obo/GO_0071272 GO:0071271 biolink:BiologicalProcess 1-butanol biosynthetic process The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O. go-plus.json 1-butanol synthesis|1-butanol formation|1-butanol biosynthesis|butanol biosynthetic process|butan-1-ol biosynthetic process|1-butanol anabolism http://purl.obolibrary.org/obo/GO_0071271 GO:0071270 biolink:BiologicalProcess 1-butanol metabolic process The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O. go-plus.json butanol metabolic process|1-butanol metabolism|butan-1-ol metabolic process http://purl.obolibrary.org/obo/GO_0071270 UBERON:0036186 biolink:AnatomicalEntity fibroelastic connective tissue go-plus.json http://purl.obolibrary.org/obo/UBERON_0036186 GO:1900169 biolink:BiologicalProcess regulation of glucocorticoid mediated signaling pathway Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway. go-plus.json regulation of glucocorticoid mediated signalling http://purl.obolibrary.org/obo/GO_1900169 GO:1900168 biolink:BiologicalProcess positive regulation of glial cell-derived neurotrophic factor production Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production. go-plus.json positive regulation of glial cell-derived neurotrophic factor secretion|positive regulation of GDNF production|positive regulation of glial cell line-derived neurotrophic factor secretion|activation of glial cell line-derived neurotrophic factor secretion http://purl.obolibrary.org/obo/GO_1900168 GO:1900165 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900165 GO:1900164 biolink:BiologicalProcess nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves. go-plus.json nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|nodal signaling of determination of left/right asymmetry in lateral mesoderm|nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm http://purl.obolibrary.org/obo/GO_1900164 GO:1900167 biolink:BiologicalProcess negative regulation of glial cell-derived neurotrophic factor production Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production. go-plus.json inhibition of glial cell line-derived neurotrophic factor secretion|negative regulation of GDNF secretion|inhibition of GDNF secretion|negative regulation of glial cell line-derived neurotrophic factor secretion|negative regulation of glial cell-derived neurotrophic factor secretion http://purl.obolibrary.org/obo/GO_1900167 GO:1900166 biolink:BiologicalProcess regulation of glial cell-derived neurotrophic factor production Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production. go-plus.json regulation of glial cell-derived neurotrophic factor secretion|regulation of glial cell line-derived neurotrophic factor secretion|regulation of GDNF secretion http://purl.obolibrary.org/obo/GO_1900166 GO:1900172 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900172 GO:1900171 biolink:BiologicalProcess positive regulation of glucocorticoid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway. go-plus.json up-regulation of glucocorticoid mediated signalling|activation of glucocorticoid mediated signalling|up regulation of glucocorticoid mediated signaling pathway|activation of glucocorticoid mediated signaling pathway|positive regulation of glucocorticoid mediated signalling|up regulation of glucocorticoid mediated signalling|up-regulation of glucocorticoid mediated signaling pathway|upregulation of glucocorticoid mediated signalling|upregulation of glucocorticoid mediated signaling pathway http://purl.obolibrary.org/obo/GO_1900171 GO:1900174 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900174 GO:1900173 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900173 GO:1900170 biolink:BiologicalProcess negative regulation of glucocorticoid mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway. go-plus.json down regulation of glucocorticoid mediated signaling pathway|downregulation of glucocorticoid mediated signaling pathway|negative regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signaling pathway|downregulation of glucocorticoid mediated signalling|inhibition of glucocorticoid mediated signaling pathway|down regulation of glucocorticoid mediated signalling|inhibition of glucocorticoid mediated signalling http://purl.obolibrary.org/obo/GO_1900170 GO:0071279 biolink:BiologicalProcess cellular response to cobalt ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071279 GO:0071278 biolink:BiologicalProcess cellular response to cesium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus. go-plus.json cellular response to cesium http://purl.obolibrary.org/obo/GO_0071278 GO:0071277 biolink:BiologicalProcess cellular response to calcium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. go-plus.json cellular response to Ca2+ ion http://purl.obolibrary.org/obo/GO_0071277 GO:0071276 biolink:BiologicalProcess cellular response to cadmium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. go-plus.json cellular response to cadmium http://purl.obolibrary.org/obo/GO_0071276 OBO:GOCHE_38161 biolink:OntologyClass substance with chelator role go-plus.json http://purl.obolibrary.org/obo/GOCHE_38161 3_STAR GO:1900179 biolink:BiologicalProcess positive regulation of aflatoxin biosynthetic process Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process. go-plus.json positive regulation of aflatoxin synthesis|up regulation of aflatoxin formation|activation of aflatoxin formation|positive regulation of aflatoxin formation|positive regulation of aflatoxin biosynthesis|up regulation of aflatoxin biosynthesis|up regulation of aflatoxin biosynthetic process|up-regulation of aflatoxin anabolism|up-regulation of aflatoxin synthesis|up-regulation of aflatoxin formation|upregulation of aflatoxin anabolism|upregulation of aflatoxin biosynthesis|upregulation of aflatoxin biosynthetic process|upregulation of aflatoxin synthesis|upregulation of aflatoxin formation|activation of aflatoxin biosynthesis|up-regulation of aflatoxin biosynthetic process|up-regulation of aflatoxin biosynthesis|activation of aflatoxin biosynthetic process|up regulation of aflatoxin anabolism|activation of aflatoxin anabolism|positive regulation of aflatoxin anabolism|up regulation of aflatoxin synthesis|activation of aflatoxin synthesis http://purl.obolibrary.org/obo/GO_1900179 GO:1900176 biolink:BiologicalProcess negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm. go-plus.json down-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry http://purl.obolibrary.org/obo/GO_1900176 GO:1900175 biolink:BiologicalProcess regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm. go-plus.json regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry http://purl.obolibrary.org/obo/GO_1900175 GO:1900178 biolink:BiologicalProcess negative regulation of aflatoxin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process. go-plus.json down-regulation of aflatoxin synthesis|negative regulation of aflatoxin synthesis|down-regulation of aflatoxin formation|inhibition of aflatoxin anabolism|negative regulation of aflatoxin formation|downregulation of aflatoxin biosynthesis|downregulation of aflatoxin biosynthetic process|inhibition of aflatoxin synthesis|down regulation of aflatoxin biosynthetic process|down regulation of aflatoxin biosynthesis|inhibition of aflatoxin formation|inhibition of aflatoxin biosynthetic process|inhibition of aflatoxin biosynthesis|down regulation of aflatoxin anabolism|downregulation of aflatoxin anabolism|down regulation of aflatoxin synthesis|down regulation of aflatoxin formation|downregulation of aflatoxin synthesis|downregulation of aflatoxin formation|negative regulation of aflatoxin biosynthesis|down-regulation of aflatoxin anabolism|negative regulation of aflatoxin anabolism|down-regulation of aflatoxin biosynthetic process|down-regulation of aflatoxin biosynthesis http://purl.obolibrary.org/obo/GO_1900178 GO:1900177 biolink:BiologicalProcess regulation of aflatoxin biosynthetic process Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process. go-plus.json regulation of aflatoxin biosynthesis|regulation of aflatoxin anabolism|regulation of aflatoxin synthesis|regulation of aflatoxin formation http://purl.obolibrary.org/obo/GO_1900177 GO:1900183 biolink:BiologicalProcess regulation of xanthone-containing compound biosynthetic process Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process. go-plus.json regulation of xanthone-containing compound anabolism|regulation of xanthone-containing compound synthesis|regulation of xanthone-containing compound formation|regulation of xanthone-containing compound biosynthesis|regulation of xanthone biosynthesis|regulation of xanthone biosynthetic process http://purl.obolibrary.org/obo/GO_1900183 GO:1900182 biolink:BiologicalProcess positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. go-plus.json up-regulation of protein localisation to nucleus|up-regulation of protein localization in cell nucleus|activation of protein localization in cell nucleus|up regulation of protein localization in nucleus|upregulation of protein localization to nucleus|positive regulation of protein localization in nucleus|activation of protein localization in nucleus|upregulation of protein localisation to nucleus|up regulation of protein localization to nucleus|positive regulation of protein localization in cell nucleus|activation of protein localization to nucleus|up regulation of protein localization in cell nucleus|up-regulation of protein localization in nucleus|up regulation of protein localisation to nucleus|activation of protein localisation to nucleus|positive regulation of protein localisation to nucleus|upregulation of protein localization in cell nucleus|upregulation of protein localization in nucleus|up-regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1900182 GO:1900185 biolink:BiologicalProcess positive regulation of xanthone-containing compound biosynthetic process Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process. go-plus.json up regulation of xanthone-containing compound anabolism|activation of xanthone-containing compound formation|up regulation of xanthone biosynthesis|up regulation of xanthone biosynthetic process|positive regulation of xanthone-containing compound synthesis|positive regulation of xanthone biosynthesis|up-regulation of xanthone-containing compound biosynthetic process|positive regulation of xanthone biosynthetic process|up-regulation of xanthone-containing compound biosynthesis|up regulation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound formation|up regulation of xanthone-containing compound formation|activation of xanthone biosynthetic process|activation of xanthone biosynthesis|upregulation of xanthone-containing compound anabolism|upregulation of xanthone-containing compound biosynthetic process|upregulation of xanthone-containing compound biosynthesis|up-regulation of xanthone biosynthesis|up-regulation of xanthone biosynthetic process|upregulation of xanthone-containing compound synthesis|upregulation of xanthone-containing compound formation|up-regulation of xanthone-containing compound anabolism|up regulation of xanthone-containing compound biosynthesis|up regulation of xanthone-containing compound biosynthetic process|upregulation of xanthone biosynthetic process|upregulation of xanthone biosynthesis|up-regulation of xanthone-containing compound synthesis|activation of xanthone-containing compound biosynthetic process|positive regulation of xanthone-containing compound biosynthesis|activation of xanthone-containing compound anabolism|up-regulation of xanthone-containing compound formation|activation of xanthone-containing compound biosynthesis|activation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound anabolism http://purl.obolibrary.org/obo/GO_1900185 GO:1900184 biolink:BiologicalProcess negative regulation of xanthone-containing compound biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process. go-plus.json down-regulation of xanthone-containing compound formation|negative regulation of xanthone-containing compound formation|inhibition of xanthone-containing compound biosynthetic process|downregulation of xanthone-containing compound anabolism|negative regulation of xanthone biosynthesis|down-regulation of xanthone biosynthetic process|negative regulation of xanthone biosynthetic process|down-regulation of xanthone biosynthesis|downregulation of xanthone-containing compound synthesis|down regulation of xanthone-containing compound anabolism|inhibition of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound formation|down regulation of xanthone-containing compound synthesis|negative regulation of xanthones anabolism|inhibition of xanthone-containing compound anabolism|down regulation of xanthone-containing compound formation|down regulation of xanthone-containing compound biosynthesis|down regulation of xanthone-containing compound biosynthetic process|inhibition of xanthone biosynthetic process|inhibition of xanthone-containing compound synthesis|inhibition of xanthone biosynthesis|downregulation of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound biosynthetic process|inhibition of xanthone-containing compound formation|down regulation of xanthone biosynthetic process|down regulation of xanthone biosynthesis|down-regulation of xanthone-containing compound anabolism|negative regulation of xanthone-containing compound anabolism|negative regulation of xanthone-containing compound biosynthesis|down-regulation of xanthone-containing compound biosynthetic process|down-regulation of xanthone-containing compound biosynthesis|downregulation of xanthone biosynthetic process|downregulation of xanthone biosynthesis|down-regulation of xanthone-containing compound synthesis|negative regulation of xanthone-containing compound synthesis http://purl.obolibrary.org/obo/GO_1900184 GO:1900181 biolink:BiologicalProcess negative regulation of protein localization to nucleus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. go-plus.json inhibition of protein localisation to nucleus|down regulation of protein localization to nucleus|negative regulation of protein localization in cell nucleus|negative regulation of protein localization in nucleus|down-regulation of protein localization in nucleus|down-regulation of protein localization in cell nucleus|downregulation of protein localization to nucleus|down regulation of protein localisation to nucleus|inhibition of protein localization in nucleus|downregulation of protein localisation to nucleus|downregulation of protein localization in cell nucleus|down-regulation of protein localization to nucleus|down regulation of protein localization in cell nucleus|inhibition of protein localization in cell nucleus|negative regulation of protein localisation to nucleus|down-regulation of protein localisation to nucleus|inhibition of protein localization to nucleus|down regulation of protein localization in nucleus|downregulation of protein localization in nucleus http://purl.obolibrary.org/obo/GO_1900181 GO:1900180 biolink:BiologicalProcess regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of protein localization to nucleus. go-plus.json regulation of protein localisation to nucleus|regulation of protein localization in cell nucleus|regulation of protein localization in nucleus http://purl.obolibrary.org/obo/GO_1900180 GO:0071297 biolink:BiologicalProcess cellular response to cobalamin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus. go-plus.json cellular response to vitamin B12 http://purl.obolibrary.org/obo/GO_0071297 GO:0071296 biolink:BiologicalProcess cellular response to biotin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus. go-plus.json cellular response to vitamin B7|cellular response to vitamin H|cellular response to coenzyme R|cellular response to Bios IIB http://purl.obolibrary.org/obo/GO_0071296 GO:0071295 biolink:BiologicalProcess cellular response to vitamin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071295 GO:0071294 biolink:BiologicalProcess cellular response to zinc ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. go-plus.json cellular response to zinc http://purl.obolibrary.org/obo/GO_0071294 GO:0071293 biolink:BiologicalProcess cellular response to tellurium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus. go-plus.json cellular response to tellurium http://purl.obolibrary.org/obo/GO_0071293 GO:0071292 biolink:BiologicalProcess cellular response to silver ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071292 GO:0071291 biolink:BiologicalProcess cellular response to selenium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion. go-plus.json http://purl.obolibrary.org/obo/GO_0071291 GO:0071290 biolink:BiologicalProcess cellular response to platinum ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus. go-plus.json cellular response to platinum http://purl.obolibrary.org/obo/GO_0071290 GO:1900187 biolink:BiologicalProcess regulation of cell adhesion involved in single-species biofilm formation Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation. go-plus.json regulation of cell adhesion during single-species biofilm formation http://purl.obolibrary.org/obo/GO_1900187 GO:1900186 biolink:BiologicalProcess negative regulation of clathrin-dependent endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis. go-plus.json inhibition of clathrin coated pit-dependent endocytosis|down-regulation of clathrin-mediated endocytosis|downregulation of clathrin-dependent endocytosis|down regulation of clathrin coated pit-dependent endocytosis|down regulation of clathrin-dependent endocytosis|inhibition of clathrin-mediated endocytosis|downregulation of clathrin coated pit-dependent endocytosis|inhibition of clathrin-dependent endocytosis|negative regulation of clathrin-mediated endocytosis|negative regulation of clathrin coated pit-dependent endocytosis|down-regulation of clathrin coated pit-dependent endocytosis|down regulation of clathrin-mediated endocytosis|downregulation of clathrin-mediated endocytosis|negative regulation of clathrin-dependent endocytosis|down-regulation of clathrin-dependent endocytosis http://purl.obolibrary.org/obo/GO_1900186 GO:1900189 biolink:BiologicalProcess positive regulation of cell adhesion involved in single-species biofilm formation Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation. go-plus.json up regulation of cell adhesion during single-species biofilm formation|up-regulation of cell adhesion involved in single-species biofilm formation|positive regulation of cell adhesion during single-species biofilm formation|activation of cell adhesion involved in single-species biofilm formation|activation of cell adhesion during single-species biofilm formation|up-regulation of cell adhesion during single-species biofilm formation|up regulation of cell adhesion involved in single-species biofilm formation|upregulation of cell adhesion during single-species biofilm formation|upregulation of cell adhesion involved in single-species biofilm formation http://purl.obolibrary.org/obo/GO_1900189 GO:1900188 biolink:BiologicalProcess negative regulation of cell adhesion involved in single-species biofilm formation Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation. go-plus.json downregulation of cell adhesion during single-species biofilm formation|down-regulation of cell adhesion during single-species biofilm formation|negative regulation of cell adhesion during single-species biofilm formation|down-regulation of cell adhesion involved in single-species biofilm formation|downregulation of cell adhesion involved in single-species biofilm formation|inhibition of cell adhesion during single-species biofilm formation|down regulation of cell adhesion involved in single-species biofilm formation|inhibition of cell adhesion involved in single-species biofilm formation|down regulation of cell adhesion during single-species biofilm formation http://purl.obolibrary.org/obo/GO_1900188 GO:1900194 biolink:BiologicalProcess negative regulation of oocyte maturation Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. go-plus.json downregulation of oocyte maturation|down-regulation of oocyte maturation|inhibition of oocyte maturation|down regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_1900194 GO:1900193 biolink:BiologicalProcess regulation of oocyte maturation Any process that modulates the frequency, rate or extent of oocyte maturation. go-plus.json http://purl.obolibrary.org/obo/GO_1900193 GO:1900196 biolink:BiologicalProcess regulation of penicillin biosynthetic process Any process that modulates the frequency, rate or extent of penicillin biosynthetic process. go-plus.json regulation of penicillin anabolism|regulation of penicillin synthesis|regulation of penicillin formation|regulation of penicillin biosynthesis http://purl.obolibrary.org/obo/GO_1900196 GO:1900195 biolink:BiologicalProcess positive regulation of oocyte maturation Any process that activates or increases the frequency, rate or extent of oocyte maturation. go-plus.json up regulation of oocyte maturation|activation of oocyte maturation|up-regulation of oocyte maturation|upregulation of oocyte maturation http://purl.obolibrary.org/obo/GO_1900195 GO:1900190 biolink:BiologicalProcess regulation of single-species biofilm formation Any process that modulates the frequency, rate or extent of single-species biofilm formation. go-plus.json http://purl.obolibrary.org/obo/GO_1900190 GO:1900192 biolink:BiologicalProcess positive regulation of single-species biofilm formation Any process that activates or increases the frequency, rate or extent of single-species biofilm formation. go-plus.json up-regulation of single-species biofilm formation|activation of single-species biofilm formation|up regulation of single-species biofilm formation|upregulation of single-species biofilm formation http://purl.obolibrary.org/obo/GO_1900192 GO:1900191 biolink:BiologicalProcess negative regulation of single-species biofilm formation Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation. go-plus.json down-regulation of single-species biofilm formation|downregulation of single-species biofilm formation|down regulation of single-species biofilm formation|inhibition of single-species biofilm formation http://purl.obolibrary.org/obo/GO_1900191 GO:0071299 biolink:BiologicalProcess cellular response to vitamin A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus. go-plus.json cellular response to retinol http://purl.obolibrary.org/obo/GO_0071299 GO:0071298 biolink:BiologicalProcess cellular response to L-ascorbic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus. go-plus.json cellular response to vitamin C|cellular response to ascorbic acid|cellular response to L-ascorbate http://purl.obolibrary.org/obo/GO_0071298 CHEBI:25973 biolink:ChemicalSubstance phenylacetaldehydes go-plus.json http://purl.obolibrary.org/obo/CHEBI_25973 CHEBI:25978 biolink:ChemicalSubstance phenylacetic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_25978 CHEBI:50934 biolink:ChemicalSubstance N-acyl-Delta(8)-phytosphingenine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50934 chebi_ph7_3 GO:0046206 biolink:BiologicalProcess trypanothione metabolic process The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress. go-plus.json trypanothione metabolism http://purl.obolibrary.org/obo/GO_0046206 GO:0046205 biolink:BiologicalProcess nor-spermidine catabolic process The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. go-plus.json nor-spermidine catabolism|nor-spermidine degradation|nor-spermidine breakdown http://purl.obolibrary.org/obo/GO_0046205 GO:0046204 biolink:BiologicalProcess nor-spermidine metabolic process The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. go-plus.json nor-spermidine metabolism http://purl.obolibrary.org/obo/GO_0046204 GO:0046203 biolink:BiologicalProcess spermidine catabolic process The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. go-plus.json spermidine catabolism|spermidine degradation|spermidine breakdown http://purl.obolibrary.org/obo/GO_0046203 GO:0046202 biolink:BiologicalProcess cyanide biosynthetic process The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration. go-plus.json cyanide formation|cyanide biosynthesis|cyanide anabolism|cyanide synthesis http://purl.obolibrary.org/obo/GO_0046202 CHEBI:25970 biolink:ChemicalSubstance phenoxazine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25970 GO:0046201 biolink:BiologicalProcess cyanate biosynthetic process The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid. go-plus.json cyanate anabolism|cyanate synthesis|cyanate formation|cyanate biosynthesis http://purl.obolibrary.org/obo/GO_0046201 GO:0046200 biolink:BiologicalProcess obsolete m-cresol biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of m-cresol (3-hydroxytoluene), the meta-isoform of cresol. go-plus.json m-cresol biosynthetic process|m-cresol biosynthesis|m-cresol anabolism|m-cresol synthesis|m-cresol formation http://purl.obolibrary.org/obo/GO_0046200 UBERON:0012168 biolink:AnatomicalEntity umbilical cord blood blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. go-plus.json fetal blood|cord blood|umbilical cord blood http://purl.obolibrary.org/obo/UBERON_0012168 CHEBI:84266 biolink:ChemicalSubstance 1,2-ditetradecanoyl-sn-glycerol-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84266 CHEBI:11320 biolink:ChemicalSubstance 13-hydroxydocosanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11320 chebi_ph7_3 GO:0061841 biolink:CellularComponent high-affinity iron exporter complex A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment. go-plus.json high affinity iron exporter complex|FET5-FTH1 high-affinity iron exporter complex|FET5-FTH1 high affinity iron exporter complex http://purl.obolibrary.org/obo/GO_0061841 GO:0061840 biolink:MolecularActivity high-affinity ferrous iron transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json high affinity ferrous uptake transmembrane transporter activity|high-affinity ferrous iron uptake transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0061840 CHEBI:84264 biolink:ChemicalSubstance EC 3.5.1.19 (nicotinamidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_84264 GO:0061843 biolink:BiologicalProcess Sertoli cell barrier remodeling The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle. go-plus.json restructuring of SCB|blood testis barrier restructuring|restructuring of blood-testis barrier|restructuring of BTB|Sertoli cell barrier restructuring|SCB remodeling http://purl.obolibrary.org/obo/GO_0061843 CHEBI:84263 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84263 GO:0061842 biolink:BiologicalProcess microtubule organizing center localization Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell. go-plus.json microtubule organizing center polarity|MTOC localization|MTOC polarity http://purl.obolibrary.org/obo/GO_0061842 GO:0046209 biolink:BiologicalProcess nitric oxide metabolic process The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. go-plus.json nitric oxide metabolism http://purl.obolibrary.org/obo/GO_0046209 GO:0061845 biolink:CellularComponent neuron projection branch point The location where a secondary projection arises from a neuron projection. go-plus.json http://purl.obolibrary.org/obo/GO_0061845 GO:0046208 biolink:BiologicalProcess spermine catabolic process The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging. go-plus.json spermine catabolism|spermine degradation|spermine breakdown http://purl.obolibrary.org/obo/GO_0046208 GO:0046207 biolink:BiologicalProcess trypanothione catabolic process The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress. go-plus.json trypanothione catabolism|trypanothione degradation|trypanothione breakdown http://purl.obolibrary.org/obo/GO_0046207 GO:0061844 biolink:BiologicalProcess antimicrobial humoral immune response mediated by antimicrobial peptide An immune response against microbes mediated by anti-microbial peptides in body fluid. go-plus.json peptide-mediated antimicrobial humoral response|antimicrobial peptide-mediated antimicrobial humoral response http://purl.obolibrary.org/obo/GO_0061844 GO:0061847 biolink:BiologicalProcess response to cholecystokinin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061847 GO:0061846 biolink:CellularComponent dendritic spine cytoplasm The region of the neuronal cytoplasm located in dendritic spines. go-plus.json http://purl.obolibrary.org/obo/GO_0061846 GO:0061849 biolink:MolecularActivity telomeric G-quadruplex DNA binding Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. go-plus.json http://purl.obolibrary.org/obo/GO_0061849 CHEBI:25979 biolink:ChemicalSubstance phenylacetonitrile go-plus.json http://purl.obolibrary.org/obo/CHEBI_25979 chebi_ph7_3 GO:0061848 biolink:BiologicalProcess cellular response to cholecystokinin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0061848 CHEBI:25985 biolink:ChemicalSubstance phenylalanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_25985 CHEBI:50923 biolink:ChemicalSubstance 5-deoxy-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50923 UBERON:0012152 biolink:AnatomicalEntity skeleton of pedal digitopodium A subdivision of the pes skeleton consisting of both pedal acropodial skeleton and metatarsal skeleton, but excluding the tarsal skeleton. go-plus.json pedal digitopodium http://purl.obolibrary.org/obo/UBERON_0012152 UBERON:0012151 biolink:AnatomicalEntity skeleton of manual digitopodium A subdivision of the manus skeleton consisting of both manual acropodial skeleton and metacarpal skeleton, but excluding the carpal skeleton. go-plus.json manual digitopodium http://purl.obolibrary.org/obo/UBERON_0012151 UBERON:0012150 biolink:AnatomicalEntity skeleton of digitopodium A subdivision of the autopod skeleton consisting of both acropodial skeleon and metapodial skeleton, but excluding the mesopodial/basopodial skeleton. go-plus.json digitopodium|skeleton of digits http://purl.obolibrary.org/obo/UBERON_0012150 CHEBI:50920 biolink:ChemicalSubstance 2D-2,3,5/4,6-pentahydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_50920 chebi_ph7_3 GO:0046217 biolink:BiologicalProcess indole phytoalexin metabolic process The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response. go-plus.json indole phytoalexin metabolism http://purl.obolibrary.org/obo/GO_0046217 CHEBI:50927 biolink:ChemicalSubstance angiogenesis inducing agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50927 GO:0046216 biolink:BiologicalProcess indole phytoalexin catabolic process The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response. go-plus.json indole phytoalexin breakdown|indole phytoalexin catabolism|indole phytoalexin degradation http://purl.obolibrary.org/obo/GO_0046216 CHEBI:35307 biolink:ChemicalSubstance epoxycarotenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35307 CHEBI:50926 biolink:ChemicalSubstance angiogenesis modulating agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50926 GO:0046215 biolink:BiologicalProcess siderophore catabolic process The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. go-plus.json siderochrome catabolism|siderophore degradation|siderophore catabolism|siderophore breakdown http://purl.obolibrary.org/obo/GO_0046215 CHEBI:50925 biolink:ChemicalSubstance EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50925 UBERON:0036146 biolink:AnatomicalEntity cardiopharyngeal field An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. go-plus.json http://purl.obolibrary.org/obo/UBERON_0036146 GO:0046214 biolink:BiologicalProcess enterobactin catabolic process The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. go-plus.json enterobactin catabolism|enterobactin degradation|enterobactin breakdown http://purl.obolibrary.org/obo/GO_0046214 GO:0046213 biolink:BiologicalProcess methyl ethyl ketone catabolic process The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. go-plus.json methyl ethyl ketone degradation|methyl ethyl ketone breakdown|methyl ethyl ketone catabolism http://purl.obolibrary.org/obo/GO_0046213 GO:0046212 biolink:BiologicalProcess obsolete methyl ethyl ketone biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints. go-plus.json methyl ethyl ketone anabolism|methyl ethyl ketone synthesis|methyl ethyl ketone formation|methyl ethyl ketone biosynthesis|methyl ethyl ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0046212 GO:0046211 biolink:BiologicalProcess (+)-camphor biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone. go-plus.json (+)-camphor anabolism|(+)-camphor synthesis|(+)-camphor formation|(+)-camphor biosynthesis http://purl.obolibrary.org/obo/GO_0046211 GO:0046210 biolink:BiologicalProcess nitric oxide catabolic process The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. go-plus.json nitric oxide catabolism|nitric oxide degradation|nitric oxide breakdown http://purl.obolibrary.org/obo/GO_0046210 CHEBI:35300 biolink:ChemicalSubstance ortho- and peri-fused polycyclic arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35300 CHEBI:84276 biolink:ChemicalSubstance methyl phenyl(piperidin-2-yl)acetate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84276 GO:0061830 biolink:CellularComponent concave side of sperm head The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species. go-plus.json http://purl.obolibrary.org/obo/GO_0061830 CHEBI:84274 biolink:ChemicalSubstance (E)-dodec-2-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84274 chebi_ph7_3 GO:0061832 biolink:CellularComponent basal ectoplasmic specialization Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell. go-plus.json basal ES http://purl.obolibrary.org/obo/GO_0061832 GO:0061831 biolink:CellularComponent apical ectoplasmic specialization Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell. go-plus.json apical ES http://purl.obolibrary.org/obo/GO_0061831 GO:0061834 biolink:CellularComponent actin filament branch point The part of an actin filament where the structure forks. go-plus.json microfilament branch point http://purl.obolibrary.org/obo/GO_0061834 CHEBI:35306 biolink:ChemicalSubstance 9'-cis-neoxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35306 chebi_ph7_3 GO:0046219 biolink:BiologicalProcess indolalkylamine biosynthetic process The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. go-plus.json indolalkylamine anabolism|indolalkylamine synthesis|indolalkylamine biosynthesis|indolalkylamine formation http://purl.obolibrary.org/obo/GO_0046219 CHEBI:35305 biolink:ChemicalSubstance 9-cis-violaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35305 chebi_ph7_3 GO:0046218 biolink:BiologicalProcess indolalkylamine catabolic process The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. go-plus.json indolalkylamine degradation|indolalkylamine breakdown|indolalkylamine catabolism http://purl.obolibrary.org/obo/GO_0046218 GO:0061833 biolink:BiologicalProcess protein localization to tricellular tight junction A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction. go-plus.json http://purl.obolibrary.org/obo/GO_0061833 GO:0061836 biolink:CellularComponent intranuclear rod A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions. go-plus.json intranuclear actin rod http://purl.obolibrary.org/obo/GO_0061836 GO:0061835 biolink:CellularComponent ventral surface of cell The surface of a migrating cell that is in contact with the substratum or cell layer. go-plus.json http://purl.obolibrary.org/obo/GO_0061835 GO:0061838 biolink:CellularComponent CENP-T-W-S-X complex A histone-variant containing protein complex which forms a centromere specific nucleosomal structure, involved in centromeric chromatin organization. go-plus.json http://purl.obolibrary.org/obo/GO_0061838 GO:0061837 biolink:BiologicalProcess neuropeptide processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide. go-plus.json http://purl.obolibrary.org/obo/GO_0061837 GO:0061839 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061839 GO:0046220 biolink:BiologicalProcess pyridine biosynthetic process The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor. go-plus.json pyridine anabolism|pyridine biosynthesis|pyridine synthesis|pyridine formation http://purl.obolibrary.org/obo/GO_0046220 UBERON:0036150 biolink:AnatomicalEntity skin appendage follicle An organ subunit in the skin that gives rise to cutaneous appendage. go-plus.json cutaneous appendage follicle|skin follicle|follicle http://purl.obolibrary.org/obo/UBERON_0036150 CHEBI:50912 biolink:ChemicalSubstance cardiotoxic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50912 UBERON:0012141 biolink:AnatomicalEntity manual digitopodium region A digitopodium region that is part of a manus[Obol]. This includes the fingers and metacarpal region, but excludes the carpal region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012141 UBERON:0012140 biolink:AnatomicalEntity digitopodium region A segment of the autopod consisting of both acropodial region and metapodial region, but excluding the mesopodial/basopodial region. go-plus.json acropodium (Wagner) http://purl.obolibrary.org/obo/UBERON_0012140 CHEBI:50910 biolink:ChemicalSubstance neurotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50910 GO:0046228 biolink:BiologicalProcess 2,4,5-trichlorophenoxyacetic acid catabolic process The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide. go-plus.json 2,4,5-trichlorophenoxyacetic acid degradation|2,4,5-trichlorophenoxyacetic acid breakdown|2,4,5-trichlorophenoxyacetic acid catabolism http://purl.obolibrary.org/obo/GO_0046228 CHEBI:50916 biolink:ChemicalSubstance lipid kinase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50916 GO:0046227 biolink:BiologicalProcess obsolete 2,4,5-trichlorophenoxyacetic acid biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide. go-plus.json 2,4,5-trichlorophenoxyacetic acid biosynthesis|2,4,5-trichlorophenoxyacetic acid biosynthetic process|2,4,5-trichlorophenoxyacetic acid anabolism|2,4,5-trichlorophenoxyacetic acid synthesis|2,4,5-trichlorophenoxyacetic acid formation http://purl.obolibrary.org/obo/GO_0046227 GO:0046226 biolink:BiologicalProcess coumarin catabolic process The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids. go-plus.json coumarin catabolism|coumarin degradation|coumarin breakdown http://purl.obolibrary.org/obo/GO_0046226 CHEBI:50914 biolink:ChemicalSubstance EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50914 UBERON:0012142 biolink:AnatomicalEntity pedal digitopodium region A digitopodium region that is part of a pes[Obol]. This includes the toes and metatarsal region, but excludes the tarsals region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012142 GO:0046225 biolink:BiologicalProcess bacteriocin catabolic process The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. go-plus.json bacteriocin degradation|bacteriocin catabolism|bacteriocin breakdown http://purl.obolibrary.org/obo/GO_0046225 GO:0046224 biolink:BiologicalProcess bacteriocin metabolic process The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. go-plus.json bacteriocin metabolism http://purl.obolibrary.org/obo/GO_0046224 GO:0046223 biolink:BiologicalProcess aflatoxin catabolic process The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. go-plus.json aflatoxin degradation|aflatoxin breakdown|aflatoxin catabolism http://purl.obolibrary.org/obo/GO_0046223 CHEBI:50919 biolink:ChemicalSubstance antiemetic go-plus.json http://purl.obolibrary.org/obo/CHEBI_50919 GO:0046222 biolink:BiologicalProcess aflatoxin metabolic process The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. go-plus.json aflatoxin B metabolic process|aflatoxin B2 metabolic process|aflatoxin B1 metabolic process|aflatoxin metabolism|aflatoxin B1 metabolism|aflatoxin B2 metabolism http://purl.obolibrary.org/obo/GO_0046222 CHEBI:50918 biolink:ChemicalSubstance pyrroloquinoline go-plus.json http://purl.obolibrary.org/obo/CHEBI_50918 GO:0046221 biolink:BiologicalProcess pyridine catabolic process The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor. go-plus.json pyridine catabolism|pyridine degradation|pyridine breakdown http://purl.obolibrary.org/obo/GO_0046221 GO:0061860 biolink:MolecularActivity DNA clamp unloader activity Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0061860 GO:0061863 biolink:MolecularActivity microtubule plus end polymerase Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers. go-plus.json http://purl.obolibrary.org/obo/GO_0061863 GO:0061862 biolink:BiologicalProcess cellular response to differentiation-inducing factor 2 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus. go-plus.json cellular response to DIF2|cellular response to DIF-2|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one http://purl.obolibrary.org/obo/GO_0061862 UBERON:0012139 biolink:AnatomicalEntity segment of autopod go-plus.json http://purl.obolibrary.org/obo/UBERON_0012139 GO:0061865 biolink:BiologicalProcess polarized secretion of basement membrane proteins in epithelium The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium. go-plus.json http://purl.obolibrary.org/obo/GO_0061865 GO:0061864 biolink:BiologicalProcess basement membrane constituent secretion The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061864 GO:0061867 biolink:BiologicalProcess establishment of mitotic spindle asymmetry The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061867 GO:0061866 biolink:BiologicalProcess negative regulation of histone H3-S10 phosphorylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to histone H3 on a serine residue at position 10. go-plus.json http://purl.obolibrary.org/obo/GO_0061866 GO:0046229 biolink:BiologicalProcess obsolete 2-aminobenzenesulfonate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. go-plus.json 2-aminobenzenesulphonate biosynthetic process|2-aminobenzenesulphonate biosynthesis|2-aminobenzenesulfonate anabolism|2-aminobenzenesulfonate synthesis|2-aminobenzenesulfonate biosynthetic process|2-aminobenzenesulfonate biosynthesis|2-aminobenzenesulfonate formation http://purl.obolibrary.org/obo/GO_0046229 GO:0061869 biolink:BiologicalProcess regulation of hepatic stellate cell migration Any process that modulates the frequency, rate or extent of hepatic stellate cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0061869 GO:0061868 biolink:BiologicalProcess hepatic stellate cell migration The orderly movement of a hepatic stellate cell from one site to another. go-plus.json http://purl.obolibrary.org/obo/GO_0061868 GO:0046231 biolink:BiologicalProcess obsolete carbazole biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. go-plus.json carbazole anabolism|carbazole synthesis|carbazole formation|carbazole biosynthetic process|carbazole biosynthesis http://purl.obolibrary.org/obo/GO_0046231 GO:0046230 biolink:BiologicalProcess 2-aminobenzenesulfonate catabolic process The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. go-plus.json 2-aminobenzenesulfonate catabolism|2-aminobenzenesulphonate catabolic process|2-aminobenzenesulphonate catabolism|2-aminobenzenesulfonate degradation|2-aminobenzenesulfonate breakdown http://purl.obolibrary.org/obo/GO_0046230 CHEBI:25961 biolink:ChemicalSubstance phenanthrenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_25961 GO:0046239 biolink:BiologicalProcess phthalate catabolic process The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid. go-plus.json phthalate degradation|phthalate breakdown|phthalate catabolism http://purl.obolibrary.org/obo/GO_0046239 CHEBI:50905 biolink:ChemicalSubstance teratogenic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50905 GO:0046238 biolink:BiologicalProcess obsolete phthalate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of phthalate, any ester or salt of phthalic acid. go-plus.json phthalate anabolism|phthalate biosynthesis|phthalate biosynthetic process|phthalate synthesis|phthalate formation http://purl.obolibrary.org/obo/GO_0046238 CHEBI:50904 biolink:ChemicalSubstance allergen go-plus.json http://purl.obolibrary.org/obo/CHEBI_50904 GO:0046237 biolink:BiologicalProcess obsolete phenanthrene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of phenanthrene, a tricyclic aromatic hydrocarbon. go-plus.json phenanthrene anabolism|phenanthrene synthesis|phenanthrene biosynthesis|phenanthrene biosynthetic process|phenanthrene formation http://purl.obolibrary.org/obo/GO_0046237 CHEBI:50903 biolink:ChemicalSubstance carcinogenic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50903 GO:0046236 biolink:BiologicalProcess mandelate biosynthetic process The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic. go-plus.json mandelate anabolism|mandelate synthesis|mandelate formation|mandelate biosynthesis http://purl.obolibrary.org/obo/GO_0046236 CHEBI:50902 biolink:ChemicalSubstance genotoxin go-plus.json http://purl.obolibrary.org/obo/CHEBI_50902 GO:0046235 biolink:BiologicalProcess obsolete gallate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). go-plus.json gallic acid biosynthetic process|gallic acid biosynthesis|gallate biosynthesis|gallate anabolism|gallate synthesis|gallate formation http://purl.obolibrary.org/obo/GO_0046235 CHEBI:50909 biolink:ChemicalSubstance nephrotoxic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50909 GO:0046234 biolink:BiologicalProcess obsolete fluorene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents. go-plus.json fluorene biosynthetic process|fluorene biosynthesis|fluorene anabolism|fluorene synthesis|fluorene formation http://purl.obolibrary.org/obo/GO_0046234 CHEBI:50908 biolink:ChemicalSubstance hepatotoxic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50908 GO:0046233 biolink:BiologicalProcess obsolete 3-hydroxyphenylacetate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate. go-plus.json 3-hydroxyphenylacetate biosynthesis|3-hydroxyphenylacetate biosynthetic process|3-hydroxyphenylacetate anabolism|3-hydroxyphenylacetate synthesis|3-hydroxyphenylacetate formation http://purl.obolibrary.org/obo/GO_0046233 GO:0046232 biolink:BiologicalProcess carbazole catabolic process The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. go-plus.json carbazole breakdown|carbazole catabolism|carbazole degradation http://purl.obolibrary.org/obo/GO_0046232 CHEBI:50906 biolink:ChemicalSubstance role go-plus.json http://purl.obolibrary.org/obo/CHEBI_50906 GO:0061850 biolink:CellularComponent growth cone leading edge That part of the growth cone which represents the distal part of the structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061850 CHEBI:84299 biolink:ChemicalSubstance 1-myristoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84299 chebi_ph7_3 GO:0061852 biolink:CellularComponent retrograte transporter complex, Golgi to ER Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles. go-plus.json retrograte receptor complex, Golgi to ER|ERV41-ERV46 retrograde receptor complex|retrograte receptor complex, Golgi to endoplasmic reticulum|retrograte transporter complex, Golgi to endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0061852 GO:0061851 biolink:CellularComponent leading edge of lamellipodium That part of the lamellipodium which represents the distal part of the structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061851 GO:0061854 biolink:BiologicalProcess positive regulation of neuroblast migration Any process that activates or increases the frequency, rate or extent of neuroblast migration. go-plus.json http://purl.obolibrary.org/obo/GO_0061854 GO:0061853 biolink:BiologicalProcess regulation of neuroblast migration Any process that modulates the frequency, rate or extent of neuroblast migration. go-plus.json http://purl.obolibrary.org/obo/GO_0061853 GO:0061856 biolink:BiologicalProcess Golgi calcium ion transmembrane transport A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0061856 GO:0061855 biolink:BiologicalProcess negative regulation of neuroblast migration Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration. go-plus.json http://purl.obolibrary.org/obo/GO_0061855 GO:0061857 biolink:BiologicalProcess endoplasmic reticulum stress-induced pre-emptive quality control The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome. go-plus.json ER stress-indiced pre-emptive quality control|ER pQC http://purl.obolibrary.org/obo/GO_0061857 CHEBI:84291 biolink:ChemicalSubstance organic sulfur anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84291 GO:0046242 biolink:BiologicalProcess obsolete o-xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. go-plus.json o-xylene anabolism|ortho-xylene biosynthetic process|ortho-xylene biosynthesis|o-xylene synthesis|o-xylene formation|o-xylene biosynthesis|o-xylene biosynthetic process http://purl.obolibrary.org/obo/GO_0046242 GO:0046241 biolink:BiologicalProcess obsolete m-xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon. go-plus.json m-xylene anabolism|m-xylene synthesis|m-xylene formation|m-xylene biosynthetic process|m-xylene biosynthesis|meta-xylene biosynthesis|meta-xylene biosynthetic process http://purl.obolibrary.org/obo/GO_0046241 GO:0046240 biolink:BiologicalProcess obsolete xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. go-plus.json xylene anabolism|xylene synthesis|xylene formation|xylene biosynthesis|xylene biosynthetic process http://purl.obolibrary.org/obo/GO_0046240 CHEBI:49900 biolink:ChemicalSubstance arsenous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49900 GO:0046249 biolink:BiologicalProcess alpha-pinene catabolic process The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. go-plus.json alpha-pinene degradation|alpha-pinene catabolism|alpha-pinene breakdown http://purl.obolibrary.org/obo/GO_0046249 GO:0046248 biolink:BiologicalProcess alpha-pinene biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. go-plus.json alpha-pinene biosynthesis|alpha-pinene anabolism|alpha-pinene synthesis|alpha-pinene formation http://purl.obolibrary.org/obo/GO_0046248 GO:0046247 biolink:BiologicalProcess terpene catabolic process The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units. go-plus.json terpene degradation|terpene breakdown|terpene catabolism http://purl.obolibrary.org/obo/GO_0046247 GO:0046246 biolink:BiologicalProcess terpene biosynthetic process The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units. go-plus.json terpene anabolism|terpene synthesis|terpene biosynthesis|terpene formation http://purl.obolibrary.org/obo/GO_0046246 GO:0046245 biolink:BiologicalProcess obsolete styrene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene. go-plus.json styrene formation|styrene biosynthesis|styrene biosynthetic process|styrene anabolism|styrene synthesis http://purl.obolibrary.org/obo/GO_0046245 GO:0046244 biolink:BiologicalProcess salicylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. go-plus.json salicylic acid degradation|salicylic acid breakdown|salicylic acid catabolism http://purl.obolibrary.org/obo/GO_0046244 GO:0061881 biolink:BiologicalProcess positive regulation of anterograde axonal transport of mitochondrion Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. go-plus.json positive regulation of anterograde axon transport of mitochondria http://purl.obolibrary.org/obo/GO_0061881 GO:0046243 biolink:BiologicalProcess obsolete p-xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon. go-plus.json para-xylene biosynthetic process|para-xylene biosynthesis|p-xylene anabolism|p-xylene synthesis|p-xylene formation|p-xylene biosynthesis|p-xylene biosynthetic process http://purl.obolibrary.org/obo/GO_0046243 GO:0061880 biolink:BiologicalProcess regulation of anterograde axonal transport of mitochondrion Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. go-plus.json regulation of anterograde axon transport of mitochondria http://purl.obolibrary.org/obo/GO_0061880 GO:0061883 biolink:BiologicalProcess clathrin-dependent endocytosis involved in vitellogenesis A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition. go-plus.json clathrin-dependent endocytosis involved in yolk formation http://purl.obolibrary.org/obo/GO_0061883 GO:0061882 biolink:BiologicalProcess negative regulation of anterograde axonal transport of mitochondrion Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. go-plus.json negative regulation of anterograde axon transport of mitochondria http://purl.obolibrary.org/obo/GO_0061882 GO:0061885 biolink:BiologicalProcess positive regulation of mini excitatory postsynaptic potential Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0061885 GO:0061884 biolink:BiologicalProcess regulation of mini excitatory postsynaptic potential Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0061884 GO:0061887 biolink:BiologicalProcess obsolete reproduction of symbiont in host OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms, occurring within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0061887 GO:0061886 biolink:BiologicalProcess negative regulation of mini excitatory postsynaptic potential Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0061886 GO:0071209 biolink:MolecularActivity U7 snRNA binding Binding to a U7 small nuclear RNA (U7 snRNA). go-plus.json http://purl.obolibrary.org/obo/GO_0071209 GO:0061889 biolink:BiologicalProcess negative regulation of astrocyte activation Any process that decreases the frequency, rate or extent of astrocyte activation. go-plus.json http://purl.obolibrary.org/obo/GO_0061889 GO:0071208 biolink:MolecularActivity histone pre-mRNA DCP binding Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing. go-plus.json http://purl.obolibrary.org/obo/GO_0071208 GO:0061888 biolink:BiologicalProcess regulation of astrocyte activation Any process that modulates the frequency, rate or extent of astrocyte activation. go-plus.json http://purl.obolibrary.org/obo/GO_0061888 GO:0071207 biolink:MolecularActivity histone pre-mRNA stem-loop binding Binding to a conserved stem-loop structure found in histone pre-mRNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0071207 GO:0071206 biolink:BiologicalProcess establishment of protein localization to juxtaparanode region of axon The directed movement of a protein to the juxtaparanode region of an axon. go-plus.json establishment of protein localisation to juxtaparanode region of axon http://purl.obolibrary.org/obo/GO_0071206 GO:0071205 biolink:BiologicalProcess protein localization to juxtaparanode region of axon Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon. go-plus.json protein localisation to juxtaparanode region of axon http://purl.obolibrary.org/obo/GO_0071205 GO:0071204 biolink:CellularComponent histone pre-mRNA 3'end processing complex A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1. go-plus.json histone 3'end pre-mRNA complex http://purl.obolibrary.org/obo/GO_0071204 GO:0071203 biolink:CellularComponent WASH complex A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53. go-plus.json http://purl.obolibrary.org/obo/GO_0071203 CHEBI:25935 biolink:ChemicalSubstance hydroperoxyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_25935 GO:0071202 biolink:CellularComponent Kv4.3-DPP10 channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3. CORUM:598 go-plus.json Kv4.3-DPPY channel complex http://purl.obolibrary.org/obo/GO_0071202 GO:0071201 biolink:CellularComponent Kv4.3-DPP6 channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3. CORUM:599 go-plus.json Kv4.3-DPPX channel complex http://purl.obolibrary.org/obo/GO_0071201 GO:0071200 biolink:CellularComponent Kv4.2-DPP6 channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2. CORUM:603 go-plus.json Kv4.2-DPPX channel complex http://purl.obolibrary.org/obo/GO_0071200 GO:0046253 biolink:BiologicalProcess anaerobic toluene biosynthetic process The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen. go-plus.json anaerobic toluene anabolism|anaerobic toluene synthesis|anaerobic toluene formation|anaerobic toluene biosynthesis http://purl.obolibrary.org/obo/GO_0046253 CHEBI:25941 biolink:ChemicalSubstance peroxynitrite go-plus.json http://purl.obolibrary.org/obo/CHEBI_25941 chebi_ph7_3 CHEBI:25940 biolink:ChemicalSubstance peroxides go-plus.json http://purl.obolibrary.org/obo/CHEBI_25940 chebi_ph7_3 GO:0046252 biolink:BiologicalProcess toluene biosynthetic process The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products. go-plus.json toluene biosynthesis|toluene anabolism|toluene synthesis|toluene formation http://purl.obolibrary.org/obo/GO_0046252 GO:0046251 biolink:BiologicalProcess limonene catabolic process The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. go-plus.json limonene degradation|limonene breakdown|limonene catabolism http://purl.obolibrary.org/obo/GO_0046251 GO:0046250 biolink:BiologicalProcess limonene biosynthetic process The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. go-plus.json limonene biosynthesis|limonene formation|limonene anabolism|limonene synthesis http://purl.obolibrary.org/obo/GO_0046250 CHEBI:25944 biolink:ChemicalSubstance pesticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25944 UBERON:0012193 biolink:AnatomicalEntity phrenic vein The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012193 CHEBI:25942 biolink:ChemicalSubstance peroxynitrous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25942 GO:0046259 biolink:BiologicalProcess obsolete trinitrotoluene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. go-plus.json trinitrotoluene synthesis|trinitrotoluene biosynthesis|trinitrotoluene biosynthetic process|trinitrotoluene formation|trinitrotoluene anabolism http://purl.obolibrary.org/obo/GO_0046259 GO:0046258 biolink:BiologicalProcess anaerobic 2,4,6-trinitrotoluene catabolic process The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen. go-plus.json anaerobic 2,4,6-trinitrotoluene catabolism|anaerobic 2,4,6-trinitrotoluene degradation|anaerobic 2,4,6-trinitrotoluene breakdown http://purl.obolibrary.org/obo/GO_0046258 GO:0046257 biolink:BiologicalProcess obsolete anaerobic 2,4,6-trinitrotoluene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen. go-plus.json anaerobic 2,4,6-trinitrotoluene formation|anaerobic 2,4,6-trinitrotoluene biosynthesis|anaerobic 2,4,6-trinitrotoluene biosynthetic process|anaerobic 2,4,6-trinitrotoluene anabolism|anaerobic 2,4,6-trinitrotoluene synthesis http://purl.obolibrary.org/obo/GO_0046257 GO:0046256 biolink:BiologicalProcess 2,4,6-trinitrotoluene catabolic process The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. go-plus.json 2,4,6-trinitrotoluene catabolism|2,4,6-trinitrotoluene degradation|2,4,6-trinitrotoluene breakdown http://purl.obolibrary.org/obo/GO_0046256 GO:0046255 biolink:BiologicalProcess obsolete 2,4,6-trinitrotoluene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene. go-plus.json 2,4,6-trinitrotoluene anabolism|2,4,6-trinitrotoluene synthesis|2,4,6-trinitrotoluene formation|2,4,6-trinitrotoluene biosynthesis|2,4,6-trinitrotoluene biosynthetic process http://purl.obolibrary.org/obo/GO_0046255 GO:0061870 biolink:BiologicalProcess positive regulation of hepatic stellate cell migration Any process that increases the frequency, rate or extent of hepatic stellate cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0061870 GO:0046254 biolink:BiologicalProcess anaerobic toluene catabolic process The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen. MetaCyc:PWY-81 go-plus.json anaerobic toluene degradation|anaerobic toluene catabolism|anaerobic toluene breakdown http://purl.obolibrary.org/obo/GO_0046254 GO:0061872 biolink:BiologicalProcess hepatic stellate cell contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell. go-plus.json http://purl.obolibrary.org/obo/GO_0061872 GO:0061871 biolink:BiologicalProcess negative regulation of hepatic stellate cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration. go-plus.json http://purl.obolibrary.org/obo/GO_0061871 GO:0061874 biolink:BiologicalProcess positive regulation of hepatic stellate cell contraction Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0061874 GO:0061873 biolink:BiologicalProcess regulation of hepatic stellate cell contraction Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0061873 GO:0061875 biolink:BiologicalProcess negative regulation of hepatic stellate cell contraction Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction. go-plus.json http://purl.obolibrary.org/obo/GO_0061875 GO:0046264 biolink:BiologicalProcess obsolete thiocyanate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of thiocyanate, any anion or salt of thiocyanic acid. go-plus.json thiocyanate anabolism|thiocyanate synthesis|thiocyanate formation|thiocyanate biosynthesis|thiocyanate biosynthetic process http://purl.obolibrary.org/obo/GO_0046264 GO:0071220 biolink:BiologicalProcess cellular response to bacterial lipoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071220 GO:0046263 biolink:BiologicalProcess nitrotoluene catabolic process The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached. go-plus.json nitrotoluene catabolism|nitrotoluene degradation|nitrotoluene breakdown http://purl.obolibrary.org/obo/GO_0046263 UBERON:0012180 biolink:AnatomicalEntity head or neck skin A zone of skin that is part of a craniocervical region. go-plus.json http://purl.obolibrary.org/obo/UBERON_0012180 GO:0046262 biolink:BiologicalProcess obsolete nitrotoluene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached. go-plus.json nitrotoluene biosynthetic process|nitrotoluene biosynthesis|nitrotoluene anabolism|nitrotoluene synthesis|nitrotoluene formation http://purl.obolibrary.org/obo/GO_0046262 GO:0046261 biolink:BiologicalProcess obsolete 4-nitrotoluene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrotoluene, 1-methyl-4-nitrobenzene. go-plus.json 4-nitrotoluene synthesis|4-nitrotoluene formation|4-nitrotoluene anabolism|4NT biosynthetic process|4NT biosynthesis|4-nitrotoluene biosynthetic process|4-nitrotoluene biosynthesis http://purl.obolibrary.org/obo/GO_0046261 GO:0046260 biolink:BiologicalProcess trinitrotoluene catabolic process The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene. go-plus.json trinitrotoluene breakdown|trinitrotoluene catabolism|trinitrotoluene degradation http://purl.obolibrary.org/obo/GO_0046260 GO:0046269 biolink:BiologicalProcess toluene-4-sulfonate catabolic process The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule. go-plus.json toluene-4-sulphonate catabolism|toluene-4-sulfonate degradation|toluene-4-sulfonate breakdown|toluene-4-sulfonate catabolism|toluene-4-sulphonate catabolic process|4-toluenesulfonate catabolism|4-toluenesulfonate catabolic process http://purl.obolibrary.org/obo/GO_0046269 CHEBI:11305 biolink:ChemicalSubstance 10-hydroxycaprate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11305 chebi_ph7_3 GO:0046268 biolink:BiologicalProcess obsolete toluene-4-sulfonate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule. go-plus.json toluene-4-sulphonate biosynthesis|toluene-4-sulphonate biosynthetic process|toluene-4-sulfonate biosynthetic process|toluene-4-sulfonate biosynthesis|toluene-4-sulfonate anabolism|toluene-4-sulfonate synthesis|toluene-4-sulfonate formation|4-toluenesulfonate biosynthetic process|4-toluenesulfonate biosynthesis http://purl.obolibrary.org/obo/GO_0046268 GO:0046267 biolink:BiologicalProcess triethanolamine catabolic process The chemical reactions and pathways resulting in the breakdown of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent. go-plus.json triethanolamine degradation|triethanolamine breakdown|triethanolamine catabolism http://purl.obolibrary.org/obo/GO_0046267 GO:0046266 biolink:BiologicalProcess obsolete triethanolamine biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent. go-plus.json triethanolamine synthesis|triethanolamine biosynthesis|triethanolamine biosynthetic process|triethanolamine formation|triethanolamine anabolism http://purl.obolibrary.org/obo/GO_0046266 GO:0046265 biolink:BiologicalProcess thiocyanate catabolic process The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid. go-plus.json thiocyanate degradation|thiocyanate catabolism|thiocyanate breakdown http://purl.obolibrary.org/obo/GO_0046265 CHEBI:11302 biolink:ChemicalSubstance 10-desacetyltaxuyunnanin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_11302 chebi_ph7_3 GO:0071229 biolink:BiologicalProcess cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. go-plus.json cellular response to acid anion|cellular response to acid|cellular response to oxoanion http://purl.obolibrary.org/obo/GO_0071229 gocheck_do_not_manually_annotate GO:0071228 biolink:BiologicalProcess cellular response to tumor cell Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell. go-plus.json http://purl.obolibrary.org/obo/GO_0071228 GO:0071227 biolink:BiologicalProcess cellular response to molecule of oomycetes origin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin. go-plus.json cellular response to oomycetes associated molecule http://purl.obolibrary.org/obo/GO_0071227 CHEBI:25914 biolink:ChemicalSubstance peptidyl-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25914 GO:0071226 biolink:BiologicalProcess cellular response to molecule of fungal origin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide. go-plus.json cellular response to fungus associated molecule http://purl.obolibrary.org/obo/GO_0071226 GO:0071225 biolink:BiologicalProcess cellular response to muramyl dipeptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. go-plus.json http://purl.obolibrary.org/obo/GO_0071225 GO:0071224 biolink:BiologicalProcess cellular response to peptidoglycan Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. go-plus.json http://purl.obolibrary.org/obo/GO_0071224 GO:0071223 biolink:BiologicalProcess cellular response to lipoteichoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. go-plus.json cellular response to LTA http://purl.obolibrary.org/obo/GO_0071223 GO:0071222 biolink:BiologicalProcess cellular response to lipopolysaccharide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. go-plus.json cellular response to LPS|cellular response to endotoxin http://purl.obolibrary.org/obo/GO_0071222 GO:0071221 biolink:BiologicalProcess cellular response to bacterial lipopeptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071221 GO:0046275 biolink:BiologicalProcess flavonoid catabolic process The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton. go-plus.json flavonoid degradation|flavonoid breakdown|flavonoid catabolism http://purl.obolibrary.org/obo/GO_0046275 GO:0046274 biolink:BiologicalProcess lignin catabolic process The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units. go-plus.json lignin degradation|lignin breakdown|lignin catabolism http://purl.obolibrary.org/obo/GO_0046274 GO:0046273 biolink:BiologicalProcess lignan catabolic process The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist. go-plus.json lignan catabolism|lignan degradation|lignan breakdown http://purl.obolibrary.org/obo/GO_0046273 GO:0046272 biolink:BiologicalProcess stilbene catabolic process The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA. go-plus.json stilbene catabolism|stilbene degradation|stilbene breakdown http://purl.obolibrary.org/obo/GO_0046272 GO:0046271 biolink:BiologicalProcess phenylpropanoid catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid. go-plus.json phenylpropanoid degradation|phenylpropanoid catabolism|phenylpropanoid breakdown http://purl.obolibrary.org/obo/GO_0046271 GO:1900107 biolink:BiologicalProcess regulation of nodal signaling pathway Any process that modulates the frequency, rate or extent of nodal signaling pathway. go-plus.json regulation of nodal signalling pathway|regulation of nodal signaling http://purl.obolibrary.org/obo/GO_1900107 GO:1900106 biolink:BiologicalProcess positive regulation of hyaluranon cable assembly Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly. go-plus.json up regulation of HA cable assembly|upregulation of hyaluranon cable assembly|positive regulation of HA cable assembly|activation of HA cable assembly|up regulation of hyaluranon cable assembly|up-regulation of HA cable assembly|activation of hyaluranon cable assembly|upregulation of HA cable assembly|up-regulation of hyaluranon cable assembly http://purl.obolibrary.org/obo/GO_1900106 GO:0046270 biolink:BiologicalProcess obsolete 4-toluenecarboxylate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule. go-plus.json 4-toluenecarboxylate formation|4-toluenecarboxylate biosynthetic process|4-toluenecarboxylate biosynthesis|4-toluenecarboxylate anabolism|4-toluenecarboxylate synthesis http://purl.obolibrary.org/obo/GO_0046270 GO:1900109 biolink:BiologicalProcess regulation of histone H3-K9 dimethylation Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation. go-plus.json regulation of histone lysine H3 K9 dimethylation|regulation of histone H3 K9 dimethylation http://purl.obolibrary.org/obo/GO_1900109 UBERON:0012172 biolink:AnatomicalEntity stomach primordium A primordium that has the potential to develop into a stomach. go-plus.json stomach endoderm http://purl.obolibrary.org/obo/UBERON_0012172 CHEBI:25921 biolink:ChemicalSubstance peptidyl-glycine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25921 GO:1900108 biolink:BiologicalProcess negative regulation of nodal signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway. go-plus.json downregulation of nodal signaling pathway|down regulation of nodal signaling|down-regulation of nodal signaling pathway|downregulation of nodal signaling|inhibition of nodal signaling pathway|negative regulation of nodal signaling|down-regulation of nodal signaling|negative regulation of nodal signalling pathway|inhibition of nodal signaling|down regulation of nodal signaling pathway http://purl.obolibrary.org/obo/GO_1900108 CHEBI:25920 biolink:ChemicalSubstance peptidyl-glycine cholesteryl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_25920 GO:1900103 biolink:BiologicalProcess positive regulation of endoplasmic reticulum unfolded protein response Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response. go-plus.json activation of SREBP-mediated signalling pathway|up regulation of endoplasmic reticulum unfolded protein response|upregulation of erUPR|activation of endoplasmic reticulum unfolded protein response|up-regulation of ER unfolded protein response|up-regulation of SREBP-mediated signalling pathway|up regulation of erUPR|activation of ER unfolded protein response|positive regulation of erUPR|up-regulation of endoplasmic reticulum unfolded protein response|upregulation of SREBP-mediated signalling pathway|positive regulation of ER unfolded protein response|activation of erUPR|up regulation of ER unfolded protein response|upregulation of endoplasmic reticulum unfolded protein response|up-regulation of erUPR|up regulation of SREBP-mediated signalling pathway|positive regulation of SREBP-mediated signalling pathway|upregulation of ER unfolded protein response http://purl.obolibrary.org/obo/GO_1900103 GO:1900102 biolink:BiologicalProcess negative regulation of endoplasmic reticulum unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response. go-plus.json inhibition of ER unfolded protein response|down regulation of erUPR|down-regulation of endoplasmic reticulum unfolded protein response|downregulation of erUPR|inhibition of SREBP-mediated signalling pathway|negative regulation of ER unfolded protein response|down-regulation of ER unfolded protein response|inhibition of endoplasmic reticulum unfolded protein response|negative regulation of erUPR|down-regulation of erUPR|down regulation of SREBP-mediated signalling pathway|downregulation of ER unfolded protein response|downregulation of SREBP-mediated signalling pathway|down regulation of ER unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response|inhibition of erUPR|downregulation of endoplasmic reticulum unfolded protein response|down-regulation of SREBP-mediated signalling pathway|negative regulation of SREBP-mediated signalling pathway http://purl.obolibrary.org/obo/GO_1900102 GO:1900105 biolink:BiologicalProcess negative regulation of hyaluranon cable assembly Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly. go-plus.json downregulation of HA cable assembly|down regulation of hyaluranon cable assembly|down-regulation of HA cable assembly|negative regulation of HA cable assembly|downregulation of hyaluranon cable assembly|inhibition of HA cable assembly|down-regulation of hyaluranon cable assembly|down regulation of HA cable assembly|inhibition of hyaluranon cable assembly http://purl.obolibrary.org/obo/GO_1900105 GO:1900104 biolink:BiologicalProcess regulation of hyaluranon cable assembly Any process that modulates the frequency, rate or extent of hyaluranon cable assembly. go-plus.json regulation of HA cable assembly http://purl.obolibrary.org/obo/GO_1900104 UBERON:0012175 biolink:AnatomicalEntity acoustico-facial VII-VIII ganglion complex go-plus.json facio-acoustic ganglion complex|acousticofacial ganglion|facio-acoustic VII-VIII ganglion complex|facio-acoustic ganglion|facio-acoustic ganglion complex VII-VIII http://purl.obolibrary.org/obo/UBERON_0012175 GO:0046279 biolink:BiologicalProcess 3,4-dihydroxybenzoate biosynthetic process The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate. go-plus.json protocatechuate biosynthetic process|protocatechuate biosynthesis|protocatechuate anabolism|protocatechuate synthesis|protocatechuate formation http://purl.obolibrary.org/obo/GO_0046279 GO:0061890 biolink:BiologicalProcess positive regulation of astrocyte activation Any process that increases the frequency, rate or extent of astrocyte activation. go-plus.json http://purl.obolibrary.org/obo/GO_0061890 GO:0046278 biolink:BiologicalProcess 3,4-dihydroxybenzoate metabolic process The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid). go-plus.json protocatechuate metabolism|protocatechuate metabolic process http://purl.obolibrary.org/obo/GO_0046278 GO:1900101 biolink:BiologicalProcess regulation of endoplasmic reticulum unfolded protein response Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response. go-plus.json regulation of erUPR|regulation of SREBP-mediated signalling pathway|regulation of ER unfolded protein response http://purl.obolibrary.org/obo/GO_1900101 GO:0046277 biolink:BiologicalProcess methylgallate biosynthetic process The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid. go-plus.json methylgallate biosynthesis|methylgallate anabolism|methylgallate synthesis|methylgallate formation http://purl.obolibrary.org/obo/GO_0046277 GO:0046276 biolink:BiologicalProcess methylgallate catabolic process The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid. MetaCyc:METHYLGALLATE-DEGRADATION-PWY go-plus.json methylgallate degradation|methylgallate breakdown|methylgallate catabolism http://purl.obolibrary.org/obo/GO_0046276 GO:1900100 biolink:BiologicalProcess positive regulation of plasma cell differentiation Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. go-plus.json upregulation of plasma cell differentiation|activation of plasma cell development|up-regulation of plasma cell development|up regulation of plasma cell differentiation|activation of plasma cell differentiation|upregulation of plasma cell development|up-regulation of plasma cell differentiation|up regulation of plasma cell development|positive regulation of plasma cell development http://purl.obolibrary.org/obo/GO_1900100 GO:0061891 biolink:MolecularActivity calcium ion sensor activity Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+). go-plus.json http://purl.obolibrary.org/obo/GO_0061891 NCBITaxon:201174 biolink:OrganismalEntity Actinobacteria go-plus.json actinobacteria|Actinobacteriota|Actinobacteraeota http://purl.obolibrary.org/obo/NCBITaxon_201174 GO:0061896 biolink:MolecularActivity all-trans retinol 3,4-desaturase activity Catalysis of the reaction: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin]. RHEA:50292 go-plus.json http://purl.obolibrary.org/obo/GO_0061896 GO:0061898 biolink:MolecularActivity all-trans retinoic acid 3,4-desaturase activity Catalysis of the reaction: all-trans-retinoic acid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin]. go-plus.json http://purl.obolibrary.org/obo/GO_0061898 GO:0061897 biolink:MolecularActivity all-trans retinal 3,4-desaturase activity Catalysis of the reaction: all-trans-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin]. go-plus.json http://purl.obolibrary.org/obo/GO_0061897 GO:0071219 biolink:BiologicalProcess cellular response to molecule of bacterial origin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin. go-plus.json cellular response to bacteria associated molecule|cellular response to bacterium associated molecule|cellular response to bacterial associated molecule http://purl.obolibrary.org/obo/GO_0071219 GO:0071218 biolink:BiologicalProcess cellular response to misfolded protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071218 GO:0061899 biolink:MolecularActivity 11-cis-retinal 3,4-desaturase activity Catalysis of the reaction: 11-cis-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin]. go-plus.json http://purl.obolibrary.org/obo/GO_0061899 GO:0071217 biolink:BiologicalProcess cellular response to external biotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. go-plus.json http://purl.obolibrary.org/obo/GO_0071217 GO:0071216 biolink:BiologicalProcess cellular response to biotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. go-plus.json cellular response to biotic stress http://purl.obolibrary.org/obo/GO_0071216 gocheck_do_not_manually_annotate GO:0071215 biolink:BiologicalProcess cellular response to abscisic acid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071215 GO:0071214 biolink:BiologicalProcess cellular response to abiotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. go-plus.json cellular response to abiotic stress http://purl.obolibrary.org/obo/GO_0071214 gocheck_do_not_manually_annotate GO:0071213 biolink:BiologicalProcess cellular response to 1-aminocyclopropane-1-carboxylic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071213 GO:0071212 biolink:CellularComponent subsynaptic reticulum An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. go-plus.json SSR http://purl.obolibrary.org/obo/GO_0071212 GO:0071211 biolink:BiologicalProcess protein targeting to vacuole involved in autophagy The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm. go-plus.json protein targeting to autophagosome http://purl.obolibrary.org/obo/GO_0071211 GO:0071210 biolink:BiologicalProcess protein insertion into membrane raft The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. go-plus.json establishment of protein localization to membrane raft http://purl.obolibrary.org/obo/GO_0071210 CHEBI:74864 biolink:ChemicalSubstance ribose derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_74864 CHEBI:132924 biolink:ChemicalSubstance sulfoglycolithocholate anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_132924 CHEBI:35256 biolink:ChemicalSubstance nucleotide-glycopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35256 PR:000035716 biolink:Protein ubiquitin (RPS27A) A ubiquitin-40S ribosomal protein S27a that has been processed by proteolytic cleavage. This form is the N-terminal region consisting of the Ubiquitin (Pfam:PF00240) domain. Example: UniProtKB:P62979, 1-76. go-plus.json RPS27A/Clv:ubiq http://purl.obolibrary.org/obo/PR_000035716 CHEBI:35258 biolink:ChemicalSubstance glyco-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35258 CHEBI:35257 biolink:ChemicalSubstance UDP-glycopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35257 CHEBI:35259 biolink:ChemicalSubstance benzofurans go-plus.json http://purl.obolibrary.org/obo/CHEBI_35259 UBERON:0002401 biolink:AnatomicalEntity visceral pleura The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs. go-plus.json pleura visceralis (pulmonalis)|lung pleura|pulmonary pleura|lung mesothelium|pleura visceralis|pulmonary visceral pleura|pleura pulmonalis http://purl.obolibrary.org/obo/UBERON_0002401 UBERON:0002400 biolink:AnatomicalEntity parietal pleura The outer serous membrane of the pulmonary pleural. go-plus.json pleura parietalis http://purl.obolibrary.org/obo/UBERON_0002400 UBERON:0002402 biolink:AnatomicalEntity pleural cavity The fluid-filled cavity that lies between the visceral and parietal pleurae. go-plus.json cavitum pleurale|cavitas pleuralis|cavitum pleuralae http://purl.obolibrary.org/obo/UBERON_0002402 CHEBI:50893 biolink:ChemicalSubstance azaarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50893 CHEBI:35252 biolink:ChemicalSubstance dTDP-L-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35252 CHEBI:59226 biolink:ChemicalSubstance N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_59226 CHEBI:35251 biolink:ChemicalSubstance dTDP-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35251 CHEBI:35254 biolink:ChemicalSubstance dTDP-L-talose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35254 CHEBI:35253 biolink:ChemicalSubstance dTDP-talose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35253 CHEBI:50887 biolink:ChemicalSubstance haloarene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50887 CHEBI:132939 biolink:ChemicalSubstance ethylmalonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132939 chebi_ph7_3 CHEBI:132938 biolink:ChemicalSubstance ethylmalonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132938 CHEBI:35267 biolink:ChemicalSubstance quaternary ammonium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35267 chebi_ph7_3 CHEBI:35266 biolink:ChemicalSubstance L-2-succinylamino-6-oxoheptanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35266 CHEBI:35269 biolink:ChemicalSubstance N-glycosyl amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35269 CHEBI:59210 biolink:ChemicalSubstance alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-beta-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_59210 CHEBI:60239 biolink:ChemicalSubstance beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc go-plus.json http://purl.obolibrary.org/obo/CHEBI_60239 chebi_ph7_3 CHEBI:59216 biolink:ChemicalSubstance beta-D-Galp-(1->3)-beta-D-GlcpNAc-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp go-plus.json http://purl.obolibrary.org/obo/CHEBI_59216 chebi_ph7_3 CHEBI:35262 biolink:ChemicalSubstance UDP-amino sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_35262 CHEBI:35265 biolink:ChemicalSubstance N-phospho-D-lombricine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35265 CHEBI:132908 biolink:ChemicalSubstance 5(S)-hydroperoxy-18(R)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132908 CHEBI:132909 biolink:ChemicalSubstance 5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132909 CHEBI:84209 biolink:ChemicalSubstance L-selenocysteine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84209 CHEBI:84208 biolink:ChemicalSubstance selenocysteine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84208 CHEBI:84207 biolink:ChemicalSubstance 16-hydroxyhexadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84207 chebi_ph7_3 CHEBI:84206 biolink:ChemicalSubstance 5-formyl-2-furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84206 CHEBI:84205 biolink:ChemicalSubstance 15-hydroxypentadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84205 chebi_ph7_3 CHEBI:84204 biolink:ChemicalSubstance omega-hydroxy fatty acyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84204 chebi_ph7_3 CHEBI:60240 biolink:ChemicalSubstance divalent metal cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60240 chebi_ph7_3 CHEBI:132906 biolink:ChemicalSubstance (-)-Tau-muurolol go-plus.json http://purl.obolibrary.org/obo/CHEBI_132906 chebi_ph7_3 CHEBI:84203 biolink:ChemicalSubstance 15-hydroxypentadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84203 chebi_ph7_3 CHEBI:60242 biolink:ChemicalSubstance monovalent inorganic cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60242 chebi_ph7_3 CHEBI:49883 biolink:ChemicalSubstance tetra-mu3-sulfido-tetrairon go-plus.json http://purl.obolibrary.org/obo/CHEBI_49883 chebi_ph7_3 CHEBI:84202 biolink:ChemicalSubstance 12-hydroxyoctadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84202 chebi_ph7_3 CHEBI:60245 biolink:ChemicalSubstance inositol phosphoceramide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60245 CHEBI:84201 biolink:ChemicalSubstance 12-hydroxyoctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84201 chebi_ph7_3 CHEBI:35233 biolink:ChemicalSubstance tungsten coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_35233 CL:0002088 biolink:Cell interstitial cell of Cajal This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. go-plus.json intestinal pacemaker cell|ICC http://purl.obolibrary.org/obo/CL_0002088 CHEBI:35236 biolink:ChemicalSubstance D-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35236 chebi_ph7_3 CHEBI:60247 biolink:ChemicalSubstance silver ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60247 CHEBI:35235 biolink:ChemicalSubstance L-cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35235 chebi_ph7_3 CHEBI:60249 biolink:ChemicalSubstance lead ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60249 CHEBI:35238 biolink:ChemicalSubstance amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35238 CHEBI:60248 biolink:ChemicalSubstance nickel ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60248 CHEBI:35237 biolink:ChemicalSubstance cysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35237 chebi_ph7_3 CHEBI:35239 biolink:ChemicalSubstance ADP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_35239 CL:0002085 biolink:Cell tanycyte Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle. go-plus.json stretch cell http://purl.obolibrary.org/obo/CL_0002085 CHEBI:35230 biolink:ChemicalSubstance fossil fuel go-plus.json http://purl.obolibrary.org/obo/CHEBI_35230 CHEBI:50871 biolink:ChemicalSubstance valerate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_50871 chebi_ph7_3 CHEBI:74882 biolink:ChemicalSubstance 5-(carboxymethyl)uridine 5'-monophosphate(2-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74882 chebi_ph7_3 CL:0002087 biolink:Cell nongranular leukocyte A leukocyte that lacks granules. go-plus.json agranular leukocyte http://purl.obolibrary.org/obo/CL_0002087 CHEBI:59203 biolink:ChemicalSubstance straight-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59203 CL:0002086 biolink:Cell specialized cardiac myocyte A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. go-plus.json http://purl.obolibrary.org/obo/CL_0002086 CHEBI:59202 biolink:ChemicalSubstance straight-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59202 CHEBI:74897 biolink:ChemicalSubstance 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74897 chebi_ph7_3 CHEBI:50864 biolink:ChemicalSubstance insulin-sensitizing drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_50864 CHEBI:74896 biolink:ChemicalSubstance 3'-end ribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74896 chebi_ph7_3 CHEBI:74898 biolink:ChemicalSubstance 3'-end 2'-O-methylribonucleotide(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74898 chebi_ph7_3 CHEBI:60250 biolink:ChemicalSubstance selenium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60250 CHEBI:84217 biolink:ChemicalSubstance [5-(aminomethyl)-3-furyl]methyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84217 CHEBI:60252 biolink:ChemicalSubstance lead cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60252 CHEBI:60251 biolink:ChemicalSubstance guanidinium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60251 chebi_ph7_3 CHEBI:49870 biolink:ChemicalSubstance antimonous acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_49870 chebi_ph7_3 CHEBI:84215 biolink:ChemicalSubstance gamma-glutamyltyramine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84215 CHEBI:132917 biolink:ChemicalSubstance 2-isopropylmalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132917 CHEBI:60254 biolink:ChemicalSubstance (3R)-3-(tert-butylcarbamoyl)piperazin-1-ium go-plus.json http://purl.obolibrary.org/obo/CHEBI_60254 chebi_ph7_3 CHEBI:84214 biolink:ChemicalSubstance 9-decenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84214 chebi_ph7_3 CHEBI:60253 biolink:ChemicalSubstance silver cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60253 CHEBI:84213 biolink:ChemicalSubstance 4-(phosphooxymethyl)-2-furancarboxaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_84213 CHEBI:60256 biolink:ChemicalSubstance (4R)-N-(2,3-dihydroxytetracosanoyl)-4-hydroxysphinganine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60256 chebi_ph7_3 CHEBI:84212 biolink:ChemicalSubstance furan-2,5-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84212 CHEBI:35245 biolink:ChemicalSubstance GDP-galactose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35245 CHEBI:35244 biolink:ChemicalSubstance nucleotide-oligosaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35244 CHEBI:60255 biolink:ChemicalSubstance puromycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60255 chebi_ph7_3 CHEBI:84211 biolink:ChemicalSubstance 5-(dihydroxymethyl)-2-furoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84211 CHEBI:35247 biolink:ChemicalSubstance D-serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35247 chebi_ph7_3 CHEBI:60258 biolink:ChemicalSubstance EC 3.4.* (hydrolases acting on peptide bond) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_60258 CHEBI:60257 biolink:ChemicalSubstance N(omega)-methyl-L-arginine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60257 CHEBI:35248 biolink:ChemicalSubstance dTDP-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35248 CL:0002092 biolink:Cell bone marrow cell A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. go-plus.json http://purl.obolibrary.org/obo/CL_0002092 CHEBI:74890 biolink:ChemicalSubstance N(1)-methylpseudouridine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74890 chebi_ph7_3 CHEBI:35241 biolink:ChemicalSubstance nucleotide-carbohydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35241 CHEBI:50860 biolink:ChemicalSubstance organic molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_50860 CHEBI:74892 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74892 chebi_ph7_3 CHEBI:35240 biolink:ChemicalSubstance nucleotide-alditol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35240 CHEBI:35243 biolink:ChemicalSubstance serine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35243 chebi_ph7_3 CL:0002098 biolink:Cell regular cardiac myocyte A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval. go-plus.json regular cardiac muscle cell|regular cardiac muscle fiber http://purl.obolibrary.org/obo/CL_0002098 CHEBI:74894 biolink:ChemicalSubstance N(3)-methylcytidine 5'-monophosphate(1-) residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74894 chebi_ph7_3 CL:0002097 biolink:Cell cortical cell of adrenal gland A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol. go-plus.json adrenal cortex cell|adrenocortical cell http://purl.obolibrary.org/obo/CL_0002097 CHEBI:35242 biolink:ChemicalSubstance CDP-D-glucose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35242 CHEBI:25897 biolink:ChemicalSubstance pentenoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25897 CHEBI:50857 biolink:ChemicalSubstance anti-allergic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50857 UBERON:0002437 biolink:AnatomicalEntity cerebral hemisphere white matter White matter that is part of a cerebral hemisphere. go-plus.json cerebral white matter|region of cerebral white matter|substantia medullaris cerebri|cerebral hemisphere white matter|white matter structure of cerebral hemisphere|hemisphere white matter http://purl.obolibrary.org/obo/UBERON_0002437 CHEBI:25899 biolink:ChemicalSubstance pentitol go-plus.json http://purl.obolibrary.org/obo/CHEBI_25899 CHEBI:50855 biolink:ChemicalSubstance antiatherogenic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_50855 CHEBI:25898 biolink:ChemicalSubstance pentitol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25898 GO:0046404 biolink:MolecularActivity polydeoxyribonucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA. MetaCyc:POLYNUCLEOTIDE-5-HYDROXYL-KINASE-RXN|RHEA:15669|EC:2.7.1.78|KEGG_REACTION:R03840 go-plus.json ATP-dependent DNA 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity|ATP-dependent DNA kinase activity|ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity http://purl.obolibrary.org/obo/GO_0046404 GO:0046403 biolink:MolecularActivity polynucleotide 3'-phosphatase activity Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage. Reactome:R-HSA-5649705|EC:3.1.3.32|MetaCyc:POLYNUCLEOTIDE-3-PHOSPHATASE-RXN|RHEA:14113 go-plus.json polynucleotide 3'-phosphohydrolase activity|2'(3')-polynucleotidase activity|5'-polynucleotidekinase 3'-phosphatase activity|DNA 3'-phosphatase activity|deoxyribonucleate 3'-phosphatase activity http://purl.obolibrary.org/obo/GO_0046403 CHEBI:35219 biolink:ChemicalSubstance plant growth retardant go-plus.json http://purl.obolibrary.org/obo/CHEBI_35219 GO:0046402 biolink:BiologicalProcess O antigen metabolic process The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide. go-plus.json O antigen metabolism http://purl.obolibrary.org/obo/GO_0046402 CHEBI:60260 biolink:ChemicalSubstance 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60260 chebi_ph7_3 GO:0046401 biolink:BiologicalProcess lipopolysaccharide core region metabolic process The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains. go-plus.json lipopolysaccharide core region metabolism|LPS core region metabolic process http://purl.obolibrary.org/obo/GO_0046401 CHEBI:50858 biolink:ChemicalSubstance corticosteroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50858 GO:0046400 biolink:BiologicalProcess keto-3-deoxy-D-manno-octulosonic acid metabolic process The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria. go-plus.json KDO metabolic process|keto-3-deoxy-D-manno-octulosonic acid metabolism|KDO metabolism|ketodeoxyoctanoate metabolic process http://purl.obolibrary.org/obo/GO_0046400 CHEBI:25892 biolink:ChemicalSubstance pentanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25892 CHEBI:60267 biolink:ChemicalSubstance N(omega)-(ADP-D-ribosyl)-L-arginine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60267 chebi_ph7_3 CL:0002067 biolink:Cell type A enteroendocrine cell An enteroendocrine cell that produces glucagon. go-plus.json http://purl.obolibrary.org/obo/CL_0002067 GO:0046409 biolink:MolecularActivity p-coumarate 3-hydroxylase activity Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+. go-plus.json cytochrome P450 CYP98A3 http://purl.obolibrary.org/obo/GO_0046409 CL:0002068 biolink:Cell Purkinje myocyte Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. go-plus.json Purkinje cell fiber|Purkinje muscle cell|myocytus conducens cardiacus http://purl.obolibrary.org/obo/CL_0002068 CHEBI:35213 biolink:ChemicalSubstance cyclodepsipeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35213 CHEBI:60268 biolink:ChemicalSubstance phosphonatoformate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60268 GO:0046408 biolink:MolecularActivity chlorophyll synthetase activity Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate. KEGG_REACTION:R06284|MetaCyc:RXN1F-66|RHEA:17317|EC:2.5.1.62 go-plus.json chlorophyllide-a:phytyl-diphosphate phytyltransferase activity|chlorophyll synthase activity http://purl.obolibrary.org/obo/GO_0046408 GO:0046407 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046407 GO:0046406 biolink:MolecularActivity magnesium protoporphyrin IX methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester. MetaCyc:RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN|RHEA:17809|EC:2.1.1.11|KEGG_REACTION:R04237 go-plus.json Mg-protoporphyrin IX methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity|S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity|S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity|(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity|magnesium-protoporphyrin O-methyltransferase activity|S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity http://purl.obolibrary.org/obo/GO_0046406 CHEBI:35218 biolink:ChemicalSubstance anthocyanin cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_35218 GO:0046405 biolink:MolecularActivity glycerol dehydratase activity Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O. MetaCyc:GLYCEROL-DEHYDRATASE-RXN|EC:4.2.1.30|RHEA:19765 go-plus.json glycerol dehydrase activity|glycerol hydro-lyase (3-hydroxypropanal-forming)|glycerol hydro-lyase activity http://purl.obolibrary.org/obo/GO_0046405 CHEBI:35217 biolink:ChemicalSubstance alkaline earth coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_35217 UBERON:0002444 biolink:AnatomicalEntity lens fiber A region of the lens consisting of packed elongated enucleate cells packed with crystallin go-plus.json fibrae lentis|lens fibre|lens fibers set|lens fibers|lens fibres|set of lens fibers http://purl.obolibrary.org/obo/UBERON_0002444 UBERON:0002446 biolink:AnatomicalEntity patella A large sesamoid bone found in the distal femur/proximal tibial region of the hindlimb of tetrapods. The patella is the attachment site for proximal hindlimb tendons.[PHENOSCAPE:ad] go-plus.json knee cap|knee bone|patella http://purl.obolibrary.org/obo/UBERON_0002446 CL:0002060 biolink:Cell melanophage A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes. go-plus.json http://purl.obolibrary.org/obo/CL_0002060 CL:0002063 biolink:Cell type II pneumocyte A type II pneumocyte is a pneumocyte that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a type I pneumocyte. Thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli. go-plus.json great alveolar cell|type II alveolocyte|type 2 alveolar epithelial cell|type II alveolar cell|AT2|lung type 2 cell|granular pneumocyte|cuboidal type II cell|lung type II cell|TII|ATII|type 2 alveolocyte|type 2 pneumocyte|type II alveolar epithelial cell http://purl.obolibrary.org/obo/CL_0002063 CL:0002062 biolink:Cell type I pneumocyte A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange. go-plus.json type I alveolar epithelial cells|squamous alveolar cell|pulmonary alveolar type I cell|AT1|lung type 1 cells|membranous pneumocytes|ATI|type I alveolar cells|small alveolar cells|squamous alveolar lining cell|type 1 alveolar epithelial cells|type 1 pneumocyte http://purl.obolibrary.org/obo/CL_0002062 UBERON:0002443 biolink:AnatomicalEntity choroidal blood vessel A blood vessel that is part of a choroid [Automatically generated definition]. go-plus.json set of choroid blood vessels|blood vessel of posterior uvea|blood vessel of choroid coat|vasa sanguinea choroideae|choroid coat blood vessel|choroidea blood vessel|posterior uvea blood vessel|blood vessel of choroid|choroid blood vessels set|choroid blood vessel|blood vessel of choroidea|choroid blood vessels http://purl.obolibrary.org/obo/UBERON_0002443 UBERON:0002442 biolink:AnatomicalEntity axillary nerve trunk go-plus.json circumflex nerve trunk|trunk of right axillary nerve|right axillary neural trunk http://purl.obolibrary.org/obo/UBERON_0002442 CHEBI:50846 biolink:ChemicalSubstance immunomodulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50846 UBERON:0002427 biolink:AnatomicalEntity arm skin A zone of skin that is part of an arm [Automatically generated definition]. go-plus.json skin of arm|brachial region skin http://purl.obolibrary.org/obo/UBERON_0002427 UBERON:0002426 biolink:AnatomicalEntity chest muscle Any muscle organ that is part of a chest [Automatically generated definition]. go-plus.json muscle organ of anterolateral part of thorax|muscle organ of chest|muscle organ of front of thorax|anterolateral part of thorax muscle organ|anterior thoracic region muscle organ|muscle of thorax|muscle organ of anterior thoracic region|musculus thoracicus|front of thorax muscle organ|chest muscle organ|thoracic muscle http://purl.obolibrary.org/obo/UBERON_0002426 UBERON:0002429 biolink:AnatomicalEntity cervical lymph node Cervical lymph nodes are lymph nodes found in the neck. [WP,unvetted]. go-plus.json lymph node of neck http://purl.obolibrary.org/obo/UBERON_0002429 UBERON:0002428 biolink:AnatomicalEntity limb bone A bone that is part of a limb [Automatically generated definition]. go-plus.json bone of extremity|bone of limb|free limb bone http://purl.obolibrary.org/obo/UBERON_0002428 GO:0046415 biolink:BiologicalProcess urate metabolic process The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. go-plus.json urate metabolism http://purl.obolibrary.org/obo/GO_0046415 CHEBI:60270 biolink:ChemicalSubstance caesium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60270 GO:0046414 biolink:BiologicalProcess organomercury biosynthetic process The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom. go-plus.json organomercury anabolism|organomercury synthesis|organomercury formation|organomercury biosynthesis http://purl.obolibrary.org/obo/GO_0046414 GO:0046413 biolink:BiologicalProcess organomercury catabolic process The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom. go-plus.json organomercury degradation|organomercury catabolism|organomercury breakdown http://purl.obolibrary.org/obo/GO_0046413 CHEBI:60272 biolink:ChemicalSubstance aluminium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60272 CHEBI:50847 biolink:ChemicalSubstance immunological adjuvant go-plus.json http://purl.obolibrary.org/obo/CHEBI_50847 GO:0046412 biolink:BiologicalProcess phenylmercury acetate metabolic process The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group. go-plus.json phenylmercury acetate metabolism http://purl.obolibrary.org/obo/GO_0046412 CHEBI:60271 biolink:ChemicalSubstance tellurium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60271 GO:0046411 biolink:BiologicalProcess 2-keto-3-deoxygluconate transmembrane transport The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other. go-plus.json 2-keto-3-deoxygluconate transport http://purl.obolibrary.org/obo/GO_0046411 CHEBI:60274 biolink:ChemicalSubstance 1,2-dicaproyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60274 CHEBI:84238 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84238 GO:0046410 biolink:MolecularActivity obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity OBSOLETE. Catalysis of the reaction: 2-oxoglutarate + isochorismate = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2. go-plus.json 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity http://purl.obolibrary.org/obo/GO_0046410 CHEBI:60273 biolink:ChemicalSubstance 1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60273 CHEBI:35223 biolink:ChemicalSubstance catalyst go-plus.json http://purl.obolibrary.org/obo/CHEBI_35223 CL:0002078 biolink:Cell meso-epithelial cell Epithelial cell derived from mesoderm or mesenchyme. go-plus.json epithelial mesenchymal cell http://purl.obolibrary.org/obo/CL_0002078 CHEBI:84234 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84234 chebi_ph7_3 CL:0002077 biolink:Cell ecto-epithelial cell An epithelial cell derived from ectoderm. go-plus.json http://purl.obolibrary.org/obo/CL_0002077 CHEBI:35222 biolink:ChemicalSubstance inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35222 CHEBI:35225 biolink:ChemicalSubstance buffer go-plus.json http://purl.obolibrary.org/obo/CHEBI_35225 CHEBI:35224 biolink:ChemicalSubstance effector go-plus.json http://purl.obolibrary.org/obo/CHEBI_35224 GO:0046419 biolink:BiologicalProcess octopine metabolic process The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine. go-plus.json octopine metabolism http://purl.obolibrary.org/obo/GO_0046419 CHEBI:35227 biolink:ChemicalSubstance 4-nitrotoluene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35227 chebi_ph7_3 GO:0046418 biolink:BiologicalProcess nopaline metabolic process The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative. go-plus.json nopaline metabolism http://purl.obolibrary.org/obo/GO_0046418 GO:0046417 biolink:BiologicalProcess chorismate metabolic process The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid. go-plus.json chorismate metabolism http://purl.obolibrary.org/obo/GO_0046417 GO:0046416 biolink:BiologicalProcess D-amino acid metabolic process The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids. go-plus.json D-amino acid metabolism http://purl.obolibrary.org/obo/GO_0046416 CL:0002072 biolink:Cell nodal myocyte A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. go-plus.json P cell|myocytus nodalis|pacemaker cell|cardiac pacemaker cell http://purl.obolibrary.org/obo/CL_0002072 UBERON:0002435 biolink:AnatomicalEntity striatum A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]. go-plus.json dorsal striatum|corpus striatum (Zilles)|caudate putamen|striatum|striatum of neuraxis|neostriatum|striated nucleus|corpus striatum|neuraxis striatum|striate nucleus http://purl.obolibrary.org/obo/UBERON_0002435 CL:0002071 biolink:Cell enterocyte of epithelium of large intestine Columnar cell which populate the epithelium of large intestine and absorb water. This cell is the most numerous of the epithelial cell types in the large intestine; bear apical microvilli, contain secretory granules in their apical cytoplasm; secretion appears to be largely mucins, but is also rich in antibodies of the IgA type. go-plus.json columnar cell|vacuolar absorptive cell|columnar cell of the colon http://purl.obolibrary.org/obo/CL_0002071 CHEBI:11230 biolink:ChemicalSubstance 1-acylglycerophosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_11230 CHEBI:35221 biolink:ChemicalSubstance antimetabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_35221 CL:0002076 biolink:Cell endo-epithelial cell An epithelial cell derived from endoderm. go-plus.json http://purl.obolibrary.org/obo/CL_0002076 UBERON:0002419 biolink:AnatomicalEntity skin gland A gland that is part of a skin of body [Automatically generated definition]. go-plus.json skin glands set|skin glands|glandulae cutis|set of skin glands http://purl.obolibrary.org/obo/UBERON_0002419 CHEBI:50830 biolink:ChemicalSubstance fluorinated steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50830 CHEBI:25872 biolink:ChemicalSubstance pentacyclic triterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25872 UBERON:0002416 biolink:AnatomicalEntity integumental system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. go-plus.json body surface|integumentary system|surface|dermal system|organism surface|external covering of organism|integumentum commune http://purl.obolibrary.org/obo/UBERON_0002416 CHEBI:25879 biolink:ChemicalSubstance pentaerythritol tetranitrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25879 chebi_ph7_3 UBERON:0002415 biolink:AnatomicalEntity tail An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail go-plus.json caudal subdivision http://purl.obolibrary.org/obo/UBERON_0002415 CHEBI:25878 biolink:ChemicalSubstance pentaerythritol nitrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25878 UBERON:0002418 biolink:AnatomicalEntity cartilage tissue Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. go-plus.json cartilage tissue|cartilaginous tissue|chondrogenic tissue|cartilage|portion of cartilage tissue|cartilages http://purl.obolibrary.org/obo/UBERON_0002418 CHEBI:25876 biolink:ChemicalSubstance pentadienoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25876 UBERON:0002417 biolink:AnatomicalEntity abdominal segment of trunk The abdominal segment of the torso. go-plus.json lumbar region|lower body|abdomen/pelvis/perineum|lower trunk http://purl.obolibrary.org/obo/UBERON_0002417 GO:0046426 biolink:BiologicalProcess negative regulation of receptor signaling pathway via JAK-STAT Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT. go-plus.json negative regulation of STAT protein nuclear translocation|down-regulation of JAK-STAT cascade|downregulation of JAK-STAT cascade|down regulation of JAK-STAT cascade|inhibition of JAK-STAT cascade|negative regulation of STAT protein import into nucleus http://purl.obolibrary.org/obo/GO_0046426 GO:0046425 biolink:BiologicalProcess regulation of receptor signaling pathway via JAK-STAT Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT. go-plus.json regulation of STAT protein import into nucleus|regulation of STAT protein nuclear translocation|STAT protein import into nucleus http://purl.obolibrary.org/obo/GO_0046425 GO:0046424 biolink:MolecularActivity ferulate 5-hydroxylase activity Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+. MetaCyc:RXN-1121 go-plus.json http://purl.obolibrary.org/obo/GO_0046424 GO:0046423 biolink:MolecularActivity allene-oxide cyclase activity Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate. EC:5.3.99.6|KEGG_REACTION:R03402|RHEA:22592|MetaCyc:ALLENE-OXIDE-CYCLASE-RXN go-plus.json (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing) http://purl.obolibrary.org/obo/GO_0046423 GO:0046422 biolink:MolecularActivity violaxanthin de-epoxidase activity Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O. RHEA:32371|EC:1.23.5.1 go-plus.json VDE|violaxanthin:ascorbate oxidoreductase activity http://purl.obolibrary.org/obo/GO_0046422 GO:0046421 biolink:MolecularActivity methylisocitrate lyase activity Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate. KEGG_REACTION:R00409|RHEA:16809|MetaCyc:METHYLISOCITRATE-LYASE-RXN|EC:4.1.3.30 go-plus.json MICL|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)|2-methylisocitrate lyase activity|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity http://purl.obolibrary.org/obo/GO_0046421 GO:0046420 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046420 CHEBI:84247 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84247 CHEBI:84246 biolink:ChemicalSubstance 4-hydroxy-6-heptylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84246 chebi_ph7_3 CL:0002045 biolink:Cell Fraction A pre-pro B cell A pro-B cell that CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive. go-plus.json pre pro B cell|fraction A http://purl.obolibrary.org/obo/CL_0002045 CL:0002044 biolink:Cell Kit-positive, integrin beta7-high basophil mast progenitor cell A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002044 CHEBI:84244 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84244 CL:0002047 biolink:Cell Fraction B precursor B cell A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative. go-plus.json Fr. B|Fraction B http://purl.obolibrary.org/obo/CL_0002047 CL:0002049 biolink:Cell Fraction C precursor B cell A precursor B cell is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain. go-plus.json Fraction C http://purl.obolibrary.org/obo/CL_0002049 CHEBI:84241 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84241 GO:0046429 biolink:MolecularActivity 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin. MetaCyc:RXN0-882|RHEA:26119|EC:1.17.7.1|KEGG_REACTION:R08689 go-plus.json 1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity|1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity|(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity|(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase activity http://purl.obolibrary.org/obo/GO_0046429 CHEBI:84240 biolink:ChemicalSubstance 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84240 GO:0046428 biolink:MolecularActivity 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2. EC:2.5.1.74|MetaCyc:DMK-RXN|RHEA:30099 go-plus.json 1,4-Dihydroxy-2-naphtoate prenyltransferase activity http://purl.obolibrary.org/obo/GO_0046428 GO:0046427 biolink:BiologicalProcess positive regulation of receptor signaling pathway via JAK-STAT Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity. go-plus.json positive regulation of STAT protein nuclear translocation|up regulation of JAK-STAT cascade|upregulation of JAK-STAT cascade|stimulation of JAK-STAT cascade|activation of JAK-STAT cascade|up-regulation of JAK-STAT cascade|positive regulation of STAT protein import into nucleus http://purl.obolibrary.org/obo/GO_0046427 UBERON:0002423 biolink:AnatomicalEntity hepatobiliary system The part of the digestive system that contains the liver and the biliary system go-plus.json hepaticobiliary system|liver/biliary system|liver and biliary system http://purl.obolibrary.org/obo/UBERON_0002423 UBERON:0002422 biolink:AnatomicalEntity fourth ventricle Part of the ventricular system of the brain, forming a single large irregularly shaped cavity located on the midline of the rhombencephalon, between the medulla, pons and the isthmus ventrally and the cerebellum dorsally. It is continuous with the cerebral aqueduct anteriorally and the central canal of the spinal cord posteriorly. It communicates with the subarachnoid space through its lateral and median apertures. go-plus.json 4th ventricle|rhombencephalic vesicle|IVth ventricle|hindbrain ventricle|ventriculus quartus|ventricle of hindbrain|fourth ventricle proper|rhombencephalic ventricle|ventricle IV|ventricle of rhombencephalon http://purl.obolibrary.org/obo/UBERON_0002422 UBERON:0002425 biolink:AnatomicalEntity visceral serous pericardium Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]. go-plus.json serous visceral pericardium|epicardium|lamina visceralis pericardii serosi|visceral layer of serous pericardium|visceral lamina of serous pericardium|pericardium visceral mesothelium|visceral pericardium http://purl.obolibrary.org/obo/UBERON_0002425 UBERON:0002424 biolink:AnatomicalEntity oral epithelium An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues go-plus.json epithelium of mucosa of mouth|epithelium of oral mucosa http://purl.obolibrary.org/obo/UBERON_0002424 CL:0002041 biolink:Cell immature NK T cell stage III A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell. go-plus.json NKT.44+.NK1.1-.Th http://purl.obolibrary.org/obo/CL_0002041 CL:0002040 biolink:Cell immature NK T cell stage II A CD24-low, CD44-negative, NK1.1-negative NK T cell. go-plus.json NKT.44-NK1.1-.Th http://purl.obolibrary.org/obo/CL_0002040 UBERON:0002421 biolink:AnatomicalEntity hippocampal formation Hippocampus (proper) plus dentate gyrus and subiculum[definition derived from NIF comments and ontology alignment]. go-plus.json formatio hippocampi|archipallium|hippocampus|primal cortex|hippocampus (Crosby)|seahorse|major hippocampus http://purl.obolibrary.org/obo/UBERON_0002421 CL:0002043 biolink:Cell CD34-positive, CD38-negative multipotent progenitor cell A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002043 CL:0002042 biolink:Cell immature NK T cell stage IV A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell. go-plus.json NKT.44+.NK1.1-.Th http://purl.obolibrary.org/obo/CL_0002042 UBERON:0002420 biolink:AnatomicalEntity basal ganglion An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]. go-plus.json basal ganglion of telencephalon|basal nucleus|basal ganglia|nuclei basales http://purl.obolibrary.org/obo/UBERON_0002420 GO:1900507 biolink:BiologicalProcess negative regulation of iron-sulfur-molybdenum cofactor assembly Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly. go-plus.json inhibition of iron molybdenum cofactor biosynthesis|inhibition of iron molybdenum cofactor biosynthetic process|inhibition of FeMoco assembly|down regulation of FeMoco biosynthetic process|inhibition of iron molybdenum cofactor assembly|down regulation of iron molybdenum cofactor biosynthesis|down-regulation of iron-sulfur-molybdenum cofactor assembly|downregulation of FeMoco biosynthetic process|down regulation of iron molybdenum cofactor biosynthetic process|down regulation of FeMoco assembly|downregulation of iron molybdenum cofactor biosynthetic process|downregulation of iron molybdenum cofactor biosynthesis|downregulation of FeMoco assembly|down regulation of iron molybdenum cofactor assembly|negative regulation of FeMoco biosynthetic process|downregulation of iron-sulfur-molybdenum cofactor assembly|down-regulation of FeMoco biosynthetic process|downregulation of iron molybdenum cofactor assembly|negative regulation of iron molybdenum cofactor biosynthetic process|down-regulation of iron molybdenum cofactor biosynthesis|negative regulation of iron molybdenum cofactor biosynthesis|down-regulation of iron molybdenum cofactor biosynthetic process|down regulation of iron-sulfur-molybdenum cofactor assembly|inhibition of iron-sulfur-molybdenum cofactor assembly|down-regulation of FeMoco assembly|negative regulation of FeMoco assembly|negative regulation of iron molybdenum cofactor assembly|down-regulation of iron molybdenum cofactor assembly|inhibition of FeMoco biosynthetic process http://purl.obolibrary.org/obo/GO_1900507 UBERON:0002409 biolink:AnatomicalEntity pericardial fluid Transudate contained in the pericardial cavity.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0002409 GO:1900506 biolink:BiologicalProcess regulation of iron-sulfur-molybdenum cofactor assembly Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly. go-plus.json regulation of FeMoco biosynthetic process|regulation of iron molybdenum cofactor biosynthetic process|regulation of iron molybdenum cofactor biosynthesis|regulation of FeMoco assembly|regulation of iron molybdenum cofactor assembly http://purl.obolibrary.org/obo/GO_1900506 UBERON:0002408 biolink:AnatomicalEntity parietal serous pericardium Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac. go-plus.json lamina parietalis pericardii|parietal layer of serous pericardium|pericardial sac|parietal pericardium|lamina parietalis (pericardii serosum) http://purl.obolibrary.org/obo/UBERON_0002408 GO:1900509 biolink:BiologicalProcess regulation of pentose catabolic process to ethanol Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol. go-plus.json regulation of pentose catabolism to ethanol http://purl.obolibrary.org/obo/GO_1900509 GO:1900508 biolink:BiologicalProcess positive regulation of iron-sulfur-molybdenum cofactor assembly Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly. go-plus.json up-regulation of iron-sulfur-molybdenum cofactor assembly|upregulation of FeMoco biosynthetic process|activation of iron-sulfur-molybdenum cofactor assembly|up-regulation of iron molybdenum cofactor assembly|upregulation of iron molybdenum cofactor biosynthetic process|upregulation of iron molybdenum cofactor biosynthesis|upregulation of FeMoco assembly|up regulation of FeMoco biosynthetic process|upregulation of iron molybdenum cofactor assembly|positive regulation of FeMoco biosynthetic process|up regulation of iron-sulfur-molybdenum cofactor assembly|up regulation of iron molybdenum cofactor biosynthetic process|up regulation of iron molybdenum cofactor biosynthesis|positive regulation of iron molybdenum cofactor biosynthesis|up regulation of FeMoco assembly|positive regulation of iron molybdenum cofactor biosynthetic process|activation of FeMoco biosynthetic process|positive regulation of FeMoco assembly|up regulation of iron molybdenum cofactor assembly|activation of iron molybdenum cofactor biosynthesis|activation of iron molybdenum cofactor biosynthetic process|positive regulation of iron molybdenum cofactor assembly|up-regulation of FeMoco biosynthetic process|activation of FeMoco assembly|upregulation of iron-sulfur-molybdenum cofactor assembly|up-regulation of iron molybdenum cofactor biosynthetic process|up-regulation of iron molybdenum cofactor biosynthesis|activation of iron molybdenum cofactor assembly|up-regulation of FeMoco assembly http://purl.obolibrary.org/obo/GO_1900508 CHEBI:25883 biolink:ChemicalSubstance pentahydroxyflavone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25883 GO:1900503 biolink:BiologicalProcess regulation of cellulosome assembly Any process that modulates the frequency, rate or extent of cellulosome assembly. go-plus.json http://purl.obolibrary.org/obo/GO_1900503 UBERON:0002405 biolink:AnatomicalEntity immune system Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002405 GO:1900502 biolink:BiologicalProcess positive regulation of butyryl-CoA catabolic process to butyrate Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate. go-plus.json up regulation of butyryl-CoA catabolism to butyrate|up-regulation of butyryl-CoA catabolic process to butyrate|upregulation of butyryl-CoA catabolism to butyrate|upregulation of butyryl-CoA catabolic process to butyrate|up-regulation of butyryl-CoA catabolism to butyrate|up regulation of butyryl-CoA catabolic process to butyrate|activation of butyryl-CoA catabolism to butyrate|activation of butyryl-CoA catabolic process to butyrate|positive regulation of butyryl-CoA catabolism to butyrate http://purl.obolibrary.org/obo/GO_1900502 GO:1900505 biolink:BiologicalProcess positive regulation of cellulosome assembly Any process that activates or increases the frequency, rate or extent of cellulosome assembly. go-plus.json upregulation of cellulosome assembly|up-regulation of cellulosome assembly|activation of cellulosome assembly|up regulation of cellulosome assembly http://purl.obolibrary.org/obo/GO_1900505 UBERON:0002407 biolink:AnatomicalEntity pericardium The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002407 GO:1900504 biolink:BiologicalProcess negative regulation of cellulosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly. go-plus.json down regulation of cellulosome assembly|inhibition of cellulosome assembly|down-regulation of cellulosome assembly|downregulation of cellulosome assembly http://purl.obolibrary.org/obo/GO_1900504 UBERON:0002406 biolink:AnatomicalEntity pericardial sac a double-walled sac containing the heart and the roots of the great vessels. go-plus.json pericardium http://purl.obolibrary.org/obo/UBERON_0002406 GO:0046437 biolink:BiologicalProcess D-amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids. go-plus.json D-amino acid biosynthesis|D-amino acid anabolism|D-amino acid synthesis|D-amino acid formation http://purl.obolibrary.org/obo/GO_0046437 CHEBI:35209 biolink:ChemicalSubstance label go-plus.json http://purl.obolibrary.org/obo/CHEBI_35209 GO:0046436 biolink:BiologicalProcess D-alanine metabolic process The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid. go-plus.json D-alanine metabolism http://purl.obolibrary.org/obo/GO_0046436 CHEBI:60291 biolink:ChemicalSubstance L-alpha-phosphatidylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_60291 GO:0046435 biolink:BiologicalProcess 3-(3-hydroxy)phenylpropionate metabolic process The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate. go-plus.json 3-(3-hydroxy)phenylpropionate metabolism http://purl.obolibrary.org/obo/GO_0046435 GO:1900501 biolink:BiologicalProcess negative regulation of butyryl-CoA catabolic process to butyrate Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate. go-plus.json downregulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolic process to butyrate|down regulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolism to butyrate|down regulation of butyryl-CoA catabolic process to butyrate|downregulation of butyryl-CoA catabolic process to butyrate|down-regulation of butyryl-CoA catabolism to butyrate|negative regulation of butyryl-CoA catabolism to butyrate|down-regulation of butyryl-CoA catabolic process to butyrate http://purl.obolibrary.org/obo/GO_1900501 GO:0046434 biolink:BiologicalProcess organophosphate catabolic process The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound. go-plus.json organophosphate catabolism|organophosphate degradation|organophosphate breakdown http://purl.obolibrary.org/obo/GO_0046434 GO:1900500 biolink:BiologicalProcess regulation of butyryl-CoA catabolic process to butyrate Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate. go-plus.json regulation of butyryl-CoA catabolism to butyrate http://purl.obolibrary.org/obo/GO_1900500 GO:0046433 biolink:BiologicalProcess 2-aminoethylphosphonate metabolic process The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms. go-plus.json ciliatine metabolic process|2-phosphonoethylamine metabolic process|2-phosphonoethylamine metabolism|ciliatine metabolism|2-aminoethylphosphonate metabolism http://purl.obolibrary.org/obo/GO_0046433 CHEBI:84259 biolink:ChemicalSubstance iminoarginine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84259 CHEBI:25881 biolink:ChemicalSubstance pentahydroxycyclohexanone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25881 GO:0046432 biolink:BiologicalProcess 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A. go-plus.json 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolism http://purl.obolibrary.org/obo/GO_0046432 GO:0046431 biolink:BiologicalProcess (R)-4-hydroxymandelate metabolic process The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate). go-plus.json (R)-4-hydroxymandelate metabolism http://purl.obolibrary.org/obo/GO_0046431 GO:0046430 biolink:BiologicalProcess non-phosphorylated glucose metabolic process The chemical reactions and pathways involving non-phosphorylated forms of glucose. go-plus.json non-phosphorylated glucose metabolism http://purl.obolibrary.org/obo/GO_0046430 CHEBI:84257 biolink:ChemicalSubstance 3,6-anhydro-L-galactonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84257 CL:0002056 biolink:Cell Fraction F mature B cell A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002056 PR:000035726 biolink:Protein ubiquitin (UBB) A polyubiquitin-B that has been processed by proteolytic cleavage to produce a protein consisting of a Ubiquitin (Pfam:PF00240) domain. There are three copies of ubiquitin in polyubiquitin B. Example: UniProtKB:P0CG47, (1-76) or (77-152) or (153-228). go-plus.json UBB/Clv:ubiq http://purl.obolibrary.org/obo/PR_000035726 CHEBI:84255 biolink:ChemicalSubstance 4-hydroxy-5-methyl-6-heptadecylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84255 chebi_ph7_3 CHEBI:35203 biolink:ChemicalSubstance molybdopterins go-plus.json http://purl.obolibrary.org/obo/CHEBI_35203 CL:0002058 biolink:Cell Gr1-low non-classical monocyte A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002058 CHEBI:84253 biolink:ChemicalSubstance 4-hydroxy-5-methyl-6-pentadecylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84253 chebi_ph7_3 CHEBI:35202 biolink:ChemicalSubstance molybdenum coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_35202 PR:000035728 biolink:Protein ubiquitin A proteolytic cleavage product that gives rise to a protein that corresponds the stand-alone version of the Ubiquitin (Pfam:PF00240) domain. go-plus.json ubiquitin http://purl.obolibrary.org/obo/PR_000035728 CL:0002059 biolink:Cell CD8alpha-positive thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8alpha-positive. go-plus.json CD8alpha-alpha-positive thymic conventional dendritic cell|DC.8+.Th http://purl.obolibrary.org/obo/CL_0002059 CHEBI:84251 biolink:ChemicalSubstance 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84251 PR:000035722 biolink:Protein ubiquitin (UBA52) A ubiquitin-60S ribosomal protein L40 that has been processed by proteolytic cleavage. This form is the N-terminal region consisting of the Ubiquitin (Pfam:PF00240) domain. Example: UniProtKB:P62987, 1-76. go-plus.json UBA52/Clv:ubiq http://purl.obolibrary.org/obo/PR_000035722 CHEBI:35204 biolink:ChemicalSubstance tracer go-plus.json http://purl.obolibrary.org/obo/CHEBI_35204 GO:0046439 biolink:BiologicalProcess L-cysteine metabolic process The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid. go-plus.json L-cysteine metabolism http://purl.obolibrary.org/obo/GO_0046439 GO:0046438 biolink:BiologicalProcess D-cysteine metabolic process The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin. go-plus.json D-cysteine metabolism http://purl.obolibrary.org/obo/GO_0046438 UBERON:0002412 biolink:AnatomicalEntity vertebra The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. go-plus.json vertebrae|vertebra bone http://purl.obolibrary.org/obo/UBERON_0002412 UBERON:0002411 biolink:AnatomicalEntity clitoris the small, erectile body located at the anterior end of the vulva go-plus.json http://purl.obolibrary.org/obo/UBERON_0002411 CL:0002050 biolink:Cell Fraction C' precursor B cell A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive. go-plus.json Fraction C-prime|Fr. C' http://purl.obolibrary.org/obo/CL_0002050 PR:000035720 biolink:Protein ubiquitin (UBC) A polyubiquitin-C that has been processed by proteolytic cleavage to produce a protein consisting of a Ubiquitin (Pfam:PF00240) domain. There are nine copies of ubiquitin in polyubiquitin C. Example: UniProtKB:P0CG48, (1-76) or (77-152) or (153-228) or (229-304) or (305-380) or (381-456) or (457-532) or (533-608) or (609-684). go-plus.json UBC/Clv:ubiq http://purl.obolibrary.org/obo/PR_000035720 UBERON:0002413 biolink:AnatomicalEntity cervical vertebra A vertebra that is located in the cervical region of the vertebral column. go-plus.json vertebrae cervicales|cervical vertebrae http://purl.obolibrary.org/obo/UBERON_0002413 CL:0002052 biolink:Cell Fraction D precursor B cell A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive. go-plus.json Fr. D|Fraction D pre-B cell http://purl.obolibrary.org/obo/CL_0002052 UBERON:0002410 biolink:AnatomicalEntity autonomic nervous system The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]. go-plus.json peripheral autonomic nervous system|divisio autonomica systematis nervosi peripherici|visceral nervous system|autonomic division of peripheral nervous system|ANS|autonomic part of peripheral nervous system|pars autonomica systematis nervosi peripherici|divisio autonomica systematis nervosi peripherici http://purl.obolibrary.org/obo/UBERON_0002410 CL:0002054 biolink:Cell Fraction E immature B cell An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002054 CHEBI:59296 biolink:ChemicalSubstance alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_59296 chebi_ph7_3 CHEBI:59295 biolink:ChemicalSubstance beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_59295 chebi_ph7_3 CHEBI:59294 biolink:ChemicalSubstance alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-beta-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_59294 chebi_ph7_3 CHEBI:132988 biolink:ChemicalSubstance bradykinin(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132988 chebi_ph7_3 CHEBI:132987 biolink:ChemicalSubstance alliin zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_132987 chebi_ph7_3 CHEBI:132989 biolink:ChemicalSubstance O-acetylhomoserine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_132989 chebi_ph7_3 CHEBI:74819 biolink:ChemicalSubstance 2-methyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_74819 CHEBI:74818 biolink:ChemicalSubstance heteroaryl hydroxy compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_74818 CHEBI:132992 biolink:ChemicalSubstance radiosensitizing agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_132992 CHEBI:132966 biolink:ChemicalSubstance hippurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132966 CHEBI:59270 biolink:ChemicalSubstance 2-hydroxymyristic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59270 CHEBI:59266 biolink:ChemicalSubstance amino trisaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59266 CHEBI:132960 biolink:ChemicalSubstance 3-phosphoglycerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132960 CHEBI:35291 biolink:ChemicalSubstance all-trans-retinoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35291 chebi_ph7_3 CHEBI:35294 biolink:ChemicalSubstance carbopolycyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35294 CHEBI:35293 biolink:ChemicalSubstance fused compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35293 CHEBI:35296 biolink:ChemicalSubstance ortho-fused polycyclic arene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35296 CHEBI:35295 biolink:ChemicalSubstance homopolycyclic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35295 CHEBI:35297 biolink:ChemicalSubstance acene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35297 chebi_ph7_3 CHEBI:59268 biolink:ChemicalSubstance amino pentasaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59268 CHEBI:74831 biolink:ChemicalSubstance 1-linolenoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74831 CHEBI:74830 biolink:ChemicalSubstance 1-linoleoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74830 CHEBI:74833 biolink:ChemicalSubstance 1-linolenoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74833 CHEBI:74836 biolink:ChemicalSubstance 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74836 CHEBI:74839 biolink:ChemicalSubstance 1-oleoyl-2-stearoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74839 CHEBI:132977 biolink:ChemicalSubstance 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132977 chebi_ph7_3 CHEBI:132978 biolink:ChemicalSubstance 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132978 chebi_ph7_3 CHEBI:132970 biolink:ChemicalSubstance 5-ammoniolevulinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_132970 CHEBI:59252 biolink:ChemicalSubstance linear tetrapyrrole anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59252 CHEBI:59258 biolink:ChemicalSubstance N-hydroxy-alpha-amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59258 CHEBI:74841 biolink:ChemicalSubstance 1-heptadecanoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74841 GO:0022411 biolink:BiologicalProcess cellular component disassembly A cellular process that results in the breakdown of a cellular component. go-plus.json cellular component disassembly at cellular level|cell structure disassembly http://purl.obolibrary.org/obo/GO_0022411 goslim_pir GO:0022410 biolink:BiologicalProcess circadian sleep/wake cycle process A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. go-plus.json http://purl.obolibrary.org/obo/GO_0022410 CHEBI:74845 biolink:ChemicalSubstance 1-oleoyl-2-heptadecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74845 GO:0022413 biolink:BiologicalProcess reproductive process in single-celled organism A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism. go-plus.json http://purl.obolibrary.org/obo/GO_0022413 GO:0022412 biolink:BiologicalProcess cellular process involved in reproduction in multicellular organism A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. go-plus.json reproductive cellular process in multicellular organism http://purl.obolibrary.org/obo/GO_0022412 CHEBI:74847 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74847 CHEBI:132944 biolink:ChemicalSubstance octadec-9-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132944 chebi_ph7_3 CHEBI:74849 biolink:ChemicalSubstance 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74849 CHEBI:132943 biolink:ChemicalSubstance aspartate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132943 CHEBI:132946 biolink:ChemicalSubstance (R)-2-hydroxyglutaryl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_132946 chebi_ph7_3 CHEBI:132948 biolink:ChemicalSubstance pyridoxate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132948 CHEBI:60203 biolink:ChemicalSubstance D-glycero-alpha-D-manno-heptose 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60203 chebi_ph7_3 CHEBI:60202 biolink:ChemicalSubstance D-glycero-beta-D-manno-heptose 7-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60202 CHEBI:132940 biolink:ChemicalSubstance 1,3,7-trimethylurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132940 CHEBI:60205 biolink:ChemicalSubstance D-glycero-alpha-D-manno-heptose 1,7-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60205 CHEBI:59240 biolink:ChemicalSubstance phthiocerol A go-plus.json http://purl.obolibrary.org/obo/CHEBI_59240 chebi_ph7_3 CHEBI:60204 biolink:ChemicalSubstance D-glycero-beta-D-manno-heptose 7-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60204 chebi_ph7_3 CHEBI:132942 biolink:ChemicalSubstance quinolinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132942 CHEBI:60207 biolink:ChemicalSubstance D-glycero-alpha-D-manno-heptose 1,7-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60207 chebi_ph7_3 CHEBI:132941 biolink:ChemicalSubstance 2-hydroxyglutarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132941 CHEBI:60206 biolink:ChemicalSubstance D-glycero-beta-D-manno-heptose 1,7-bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60206 GO:0022415 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022415 GO:0022414 biolink:BiologicalProcess reproductive process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. go-plus.json single organism reproductive process http://purl.obolibrary.org/obo/GO_0022414 CHEBI:60208 biolink:ChemicalSubstance D-glycero-beta-D-manno-heptose 1,7-bisphosphate(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60208 chebi_ph7_3 GO:0022417 biolink:BiologicalProcess protein maturation by protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0022417 CHEBI:35272 biolink:ChemicalSubstance O-glycosyl amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35272 GO:0022416 biolink:BiologicalProcess chaeta development The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell. go-plus.json bristle development http://purl.obolibrary.org/obo/GO_0022416 CHEBI:35274 biolink:ChemicalSubstance ammonium ion derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_35274 CHEBI:35276 biolink:ChemicalSubstance ammonium compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35276 CHEBI:74840 biolink:ChemicalSubstance 1-heptadecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74840 CHEBI:35275 biolink:ChemicalSubstance S-glycosyl compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35275 CHEBI:74853 biolink:ChemicalSubstance 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74853 chebi_ph7_3 CHEBI:74852 biolink:ChemicalSubstance 1-oleoyl-2-pentadecanoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74852 GO:0022400 biolink:BiologicalProcess regulation of rhodopsin mediated signaling pathway Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling. go-plus.json regulation of rhodopsin mediated signalling http://purl.obolibrary.org/obo/GO_0022400 GO:0022402 biolink:BiologicalProcess cell cycle process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. go-plus.json http://purl.obolibrary.org/obo/GO_0022402 gocheck_do_not_annotate CHEBI:35290 biolink:ChemicalSubstance 1,2-dichlorobenzene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35290 chebi_ph7_3 GO:0022401 biolink:BiologicalProcess negative adaptation of signaling pathway The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. go-plus.json negative adaptation of signal transduction pathway|negative adaptation of signalling pathway http://purl.obolibrary.org/obo/GO_0022401 CHEBI:132955 biolink:ChemicalSubstance azelaate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132955 CHEBI:132954 biolink:ChemicalSubstance sebacate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132954 CHEBI:132957 biolink:ChemicalSubstance N-acetylmethioninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132957 chebi_ph7_3 CHEBI:132958 biolink:ChemicalSubstance N-acetylmethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_132958 CHEBI:35288 biolink:ChemicalSubstance all-trans-violaxanthin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35288 chebi_ph7_3 CHEBI:132951 biolink:ChemicalSubstance maleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132951 CHEBI:132950 biolink:ChemicalSubstance tartrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132950 CHEBI:60215 biolink:ChemicalSubstance W-molybdopterin cofactor go-plus.json http://purl.obolibrary.org/obo/CHEBI_60215 CHEBI:132953 biolink:ChemicalSubstance suberate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132953 CHEBI:132952 biolink:ChemicalSubstance oxalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_132952 GO:0022404 biolink:BiologicalProcess molting cycle process A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin. go-plus.json http://purl.obolibrary.org/obo/GO_0022404 CHEBI:35281 biolink:ChemicalSubstance onium betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35281 GO:0022403 biolink:BiologicalProcess cell cycle phase One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. go-plus.json http://purl.obolibrary.org/obo/GO_0022403 gocheck_do_not_annotate CHEBI:35280 biolink:ChemicalSubstance L-proline betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35280 chebi_ph7_3 GO:0022406 biolink:BiologicalProcess membrane docking The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. go-plus.json membrane docking http://purl.obolibrary.org/obo/GO_0022406 goslim_pir CHEBI:35282 biolink:ChemicalSubstance sulfonium betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35282 GO:0022405 biolink:BiologicalProcess hair cycle process A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0022405 GO:0022408 biolink:BiologicalProcess negative regulation of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. go-plus.json down-regulation of cell-cell adhesion|downregulation of cell-cell adhesion|down regulation of cell-cell adhesion|inhibition of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022408 CHEBI:59238 biolink:ChemicalSubstance cyclic fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59238 CHEBI:35285 biolink:ChemicalSubstance iminium betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35285 CHEBI:35284 biolink:ChemicalSubstance ammonium betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35284 GO:0022407 biolink:BiologicalProcess regulation of cell-cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. go-plus.json http://purl.obolibrary.org/obo/GO_0022407 CHEBI:59237 biolink:ChemicalSubstance phenolic phthiocerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_59237 chebi_ph7_3 CHEBI:35287 biolink:ChemicalSubstance acylcholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35287 chebi_ph7_3 CHEBI:74851 biolink:ChemicalSubstance 5-(2-methoxy-2-oxoethyl)uridine 5'-monophosphate residue(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74851 chebi_ph7_3 GO:0022409 biolink:BiologicalProcess positive regulation of cell-cell adhesion Any process that activates or increases the rate or extent of cell adhesion to another cell. go-plus.json activation of cell-cell adhesion|up regulation of cell-cell adhesion|upregulation of cell-cell adhesion|stimulation of cell-cell adhesion|up-regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022409 CHEBI:74850 biolink:ChemicalSubstance 1-stearoyl-sn-glycero-3-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74850 CHEBI:35286 biolink:ChemicalSubstance iminium ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35286 GO:0071363 biolink:BiologicalProcess cellular response to growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071363 GO:0071362 biolink:BiologicalProcess cellular response to ether Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071362 GO:0071361 biolink:BiologicalProcess cellular response to ethanol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071361 GO:0071360 biolink:BiologicalProcess cellular response to exogenous dsRNA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus. go-plus.json cellular response to viral dsRNA|cellular response to exogenous double-stranded RNA http://purl.obolibrary.org/obo/GO_0071360 GO:1900477 biolink:BiologicalProcess negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1900477 GO:1900476 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900476 GO:1900479 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900479 GO:1900478 biolink:BiologicalProcess obsolete positive regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of sulfate assimilation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json up-regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900478 GO:1900473 biolink:BiologicalProcess obsolete negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of phosphatidylcholine anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine formation by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900473 GO:1900472 biolink:BiologicalProcess obsolete positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of phosphatidylcholine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine biosynthesis by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900472 GO:1900475 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900475 GO:1900474 biolink:BiologicalProcess obsolete negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1900474 GO:1900480 biolink:BiologicalProcess regulation of diacylglycerol biosynthetic process Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process. go-plus.json regulation of diacylglycerol biosynthesis|regulation of diacylglycerol anabolism|regulation of diacylglycerol synthesis|regulation of diacylglycerol formation http://purl.obolibrary.org/obo/GO_1900480 GO:1900482 biolink:BiologicalProcess positive regulation of diacylglycerol biosynthetic process Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process. go-plus.json upregulation of diacylglycerol biosynthetic process|upregulation of diacylglycerol biosynthesis|activation of diacylglycerol anabolism|up-regulation of diacylglycerol formation|activation of diacylglycerol synthesis|positive regulation of diacylglycerol anabolism|up regulation of diacylglycerol anabolism|activation of diacylglycerol formation|up regulation of diacylglycerol biosynthetic process|positive regulation of diacylglycerol synthesis|up regulation of diacylglycerol biosynthesis|positive regulation of diacylglycerol biosynthesis|activation of diacylglycerol biosynthetic process|up regulation of diacylglycerol synthesis|positive regulation of diacylglycerol formation|up regulation of diacylglycerol formation|activation of diacylglycerol biosynthesis|upregulation of diacylglycerol anabolism|upregulation of diacylglycerol synthesis|up-regulation of diacylglycerol biosynthetic process|up-regulation of diacylglycerol biosynthesis|upregulation of diacylglycerol formation|up-regulation of diacylglycerol anabolism|up-regulation of diacylglycerol synthesis http://purl.obolibrary.org/obo/GO_1900482 GO:1900481 biolink:BiologicalProcess negative regulation of diacylglycerol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process. go-plus.json negative regulation of diacylglycerol anabolism|down-regulation of diacylglycerol anabolism|down regulation of diacylglycerol biosynthesis|down regulation of diacylglycerol biosynthetic process|negative regulation of diacylglycerol synthesis|down-regulation of diacylglycerol synthesis|downregulation of diacylglycerol biosynthetic process|downregulation of diacylglycerol biosynthesis|negative regulation of diacylglycerol formation|down-regulation of diacylglycerol formation|downregulation of diacylglycerol anabolism|downregulation of diacylglycerol synthesis|down regulation of diacylglycerol anabolism|down-regulation of diacylglycerol biosynthetic process|down-regulation of diacylglycerol biosynthesis|negative regulation of diacylglycerol biosynthesis|downregulation of diacylglycerol formation|down regulation of diacylglycerol synthesis|inhibition of diacylglycerol anabolism|down regulation of diacylglycerol formation|inhibition of diacylglycerol biosynthetic process|inhibition of diacylglycerol synthesis|inhibition of diacylglycerol biosynthesis|inhibition of diacylglycerol formation http://purl.obolibrary.org/obo/GO_1900481 GO:0071369 biolink:BiologicalProcess cellular response to ethylene stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus. go-plus.json cellular response to ethene stimulus http://purl.obolibrary.org/obo/GO_0071369 GO:0071368 biolink:BiologicalProcess cellular response to cytokinin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071368 GO:0071367 biolink:BiologicalProcess cellular response to brassinosteroid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071367 GO:0071366 biolink:BiologicalProcess cellular response to indolebutyric acid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus. go-plus.json cellular response to indole-3-butyric acid stimulus|cellular response to IBA stimulus http://purl.obolibrary.org/obo/GO_0071366 GO:0071365 biolink:BiologicalProcess cellular response to auxin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071365 GO:0071364 biolink:BiologicalProcess cellular response to epidermal growth factor stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. go-plus.json cellular response to EGF stimulus http://purl.obolibrary.org/obo/GO_0071364 GO:0071352 biolink:BiologicalProcess cellular response to interleukin-2 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus. go-plus.json cellular response to IL-2 http://purl.obolibrary.org/obo/GO_0071352 GO:0071351 biolink:BiologicalProcess cellular response to interleukin-18 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus. go-plus.json cellular response to IL-18 http://purl.obolibrary.org/obo/GO_0071351 GO:0071350 biolink:BiologicalProcess cellular response to interleukin-15 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus. go-plus.json cellular response to IL-15 http://purl.obolibrary.org/obo/GO_0071350 GO:1900488 biolink:BiologicalProcess negative regulation of [2Fe-2S] cluster assembly Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly. go-plus.json inhibition of 2Fe-2S cluster assembly|down-regulation of [2Fe-2S] cluster biosynthetic process|negative regulation of [2Fe-2S] cluster biosynthetic process|down-regulation of [2Fe-2S] cluster assembly|inhibition of [2Fe-2S] cluster assembly|inhibition of [2Fe-2S] cluster biosynthetic process|down regulation of 2Fe-2S cluster assembly|downregulation of 2Fe-2S cluster assembly|down regulation of [2Fe-2S] cluster biosynthetic process|down regulation of [2Fe-2S] cluster assembly|downregulation of [2Fe-2S] cluster biosynthetic process|downregulation of [2Fe-2S] cluster assembly|down-regulation of 2Fe-2S cluster assembly|negative regulation of 2Fe-2S cluster assembly http://purl.obolibrary.org/obo/GO_1900488 GO:1900487 biolink:BiologicalProcess regulation of [2Fe-2S] cluster assembly Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly. go-plus.json regulation of 2Fe-2S cluster assembly|regulation of [2Fe-2S] cluster biosynthetic process http://purl.obolibrary.org/obo/GO_1900487 GO:1900489 biolink:BiologicalProcess positive regulation of [2Fe-2S] cluster assembly Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly. go-plus.json positive regulation of [2Fe-2S] cluster biosynthetic process|activation of [2Fe-2S] cluster assembly|up-regulation of 2Fe-2S cluster assembly|activation of [2Fe-2S] cluster biosynthetic process|up-regulation of [2Fe-2S] cluster biosynthetic process|up-regulation of [2Fe-2S] cluster assembly|upregulation of 2Fe-2S cluster assembly|upregulation of [2Fe-2S] cluster biosynthetic process|upregulation of [2Fe-2S] cluster assembly|up regulation of 2Fe-2S cluster assembly|positive regulation of 2Fe-2S cluster assembly|activation of 2Fe-2S cluster assembly|up regulation of [2Fe-2S] cluster biosynthetic process|up regulation of [2Fe-2S] cluster assembly http://purl.obolibrary.org/obo/GO_1900489 GO:1900484 biolink:BiologicalProcess negative regulation of protein targeting to vacuolar membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane. go-plus.json downregulation of protein targeting to vacuolar membrane|down regulation of protein targeting to vacuolar membrane|inhibition of protein targeting to vacuolar membrane|down-regulation of protein targeting to vacuolar membrane http://purl.obolibrary.org/obo/GO_1900484 GO:1900483 biolink:BiologicalProcess regulation of protein targeting to vacuolar membrane Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_1900483 GO:1900486 biolink:BiologicalProcess positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway. go-plus.json upregulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up-regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up-regulation of isopentenyl diphosphate formation, mevalonate pathway|upregulation of isopentenyl diphosphate anabolism, mevalonate pathway|upregulation of Ac-MVA pathway|up-regulation of acetate-mevalonate pathway|up-regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|upregulation of isopentenyl diphosphate synthesis, mevalonate pathway|activation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|upregulation of isopentenyl diphosphate formation, mevalonate pathway|activation of acetate-mevalonate pathway|up regulation of isopentenyl diphosphate anabolism, mevalonate pathway|up-regulation of Ac-MVA pathway|positive regulation of isopentenyl diphosphate anabolism, mevalonate pathway|positive regulation of acetate-mevalonate pathway|up regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up regulation of acetate-mevalonate pathway|positive regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up regulation of isopentenyl diphosphate formation, mevalonate pathway|activation of isopentenyl diphosphate anabolism, mevalonate pathway|activation of Ac-MVA pathway|positive regulation of isopentenyl diphosphate formation, mevalonate pathway|activation of isopentenyl diphosphate synthesis, mevalonate pathway|positive regulation of Ac-MVA pathway|up-regulation of isopentenyl diphosphate anabolism, mevalonate pathway|up regulation of Ac-MVA pathway|activation of isopentenyl diphosphate formation, mevalonate pathway|upregulation of acetate-mevalonate pathway http://purl.obolibrary.org/obo/GO_1900486 GO:1900485 biolink:BiologicalProcess positive regulation of protein targeting to vacuolar membrane Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane. go-plus.json up regulation of protein targeting to vacuolar membrane|upregulation of protein targeting to vacuolar membrane|activation of protein targeting to vacuolar membrane|up-regulation of protein targeting to vacuolar membrane http://purl.obolibrary.org/obo/GO_1900485 GO:1900491 biolink:BiologicalProcess regulation of [4Fe-4S] cluster assembly Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly. go-plus.json regulation of [4Fe-4S] cluster biosynthetic process|regulation of 4Fe-4S cluster assembly http://purl.obolibrary.org/obo/GO_1900491 GO:1900490 biolink:BiologicalProcess positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity Any process that activates or increases the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity. go-plus.json upregulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|positive regulation of HMG-CoA reductase activity|up regulation of HMG-CoA reductase activity|upregulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up-regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|activation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|upregulation of HMG-CoA reductase activity|up-regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|activation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|up-regulation of HMG-CoA reductase activity|positive regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|activation of HMG-CoA reductase activity|up regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity http://purl.obolibrary.org/obo/GO_1900490 GO:1900493 biolink:BiologicalProcess positive regulation of [4Fe-4S] cluster assembly Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly. go-plus.json activation of 4Fe-4S cluster assembly|positive regulation of 4Fe-4S cluster assembly|upregulation of [4Fe-4S] cluster biosynthetic process|upregulation of [4Fe-4S] cluster assembly|up-regulation of 4Fe-4S cluster assembly|up regulation of [4Fe-4S] cluster biosynthetic process|up regulation of [4Fe-4S] cluster assembly|activation of [4Fe-4S] cluster assembly|positive regulation of [4Fe-4S] cluster biosynthetic process|activation of [4Fe-4S] cluster biosynthetic process|upregulation of 4Fe-4S cluster assembly|up-regulation of [4Fe-4S] cluster biosynthetic process|up-regulation of [4Fe-4S] cluster assembly|up regulation of 4Fe-4S cluster assembly http://purl.obolibrary.org/obo/GO_1900493 GO:1900492 biolink:BiologicalProcess negative regulation of [4Fe-4S] cluster assembly Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly. go-plus.json down-regulation of 4Fe-4S cluster assembly|negative regulation of 4Fe-4S cluster assembly|down regulation of [4Fe-4S] cluster biosynthetic process|down regulation of [4Fe-4S] cluster assembly|downregulation of [4Fe-4S] cluster biosynthetic process|inhibition of 4Fe-4S cluster assembly|downregulation of [4Fe-4S] cluster assembly|down-regulation of [4Fe-4S] cluster biosynthetic process|negative regulation of [4Fe-4S] cluster biosynthetic process|down-regulation of [4Fe-4S] cluster assembly|down regulation of 4Fe-4S cluster assembly|inhibition of [4Fe-4S] cluster assembly|downregulation of 4Fe-4S cluster assembly|inhibition of [4Fe-4S] cluster biosynthetic process http://purl.obolibrary.org/obo/GO_1900492 GO:0071359 biolink:BiologicalProcess cellular response to dsRNA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. go-plus.json cellular response to double-stranded RNA http://purl.obolibrary.org/obo/GO_0071359 GO:0071358 biolink:BiologicalProcess cellular response to type III interferon Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far. go-plus.json cellular response to type III IFN|cellular response to interferon-lambda http://purl.obolibrary.org/obo/GO_0071358 GO:0071357 biolink:BiologicalProcess cellular response to type I interferon Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. go-plus.json cellular response to type I IFN http://purl.obolibrary.org/obo/GO_0071357 GO:0071356 biolink:BiologicalProcess cellular response to tumor necrosis factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus. go-plus.json cellular response to TNF http://purl.obolibrary.org/obo/GO_0071356 GO:0071355 biolink:BiologicalProcess cellular response to interleukin-9 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus. go-plus.json cellular response to IL-9 http://purl.obolibrary.org/obo/GO_0071355 GO:0071354 biolink:BiologicalProcess cellular response to interleukin-6 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus. go-plus.json cellular response to IL-6 http://purl.obolibrary.org/obo/GO_0071354 GO:0071353 biolink:BiologicalProcess cellular response to interleukin-4 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus. go-plus.json cellular response to IL-4 http://purl.obolibrary.org/obo/GO_0071353 GO:0071385 biolink:BiologicalProcess cellular response to glucocorticoid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. go-plus.json http://purl.obolibrary.org/obo/GO_0071385 GO:0071384 biolink:BiologicalProcess cellular response to corticosteroid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. go-plus.json http://purl.obolibrary.org/obo/GO_0071384 GO:0071383 biolink:BiologicalProcess cellular response to steroid hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071383 GO:0071382 biolink:BiologicalProcess cellular response to prostaglandin I stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071382 GO:0071381 biolink:BiologicalProcess cellular response to prostaglandin F stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071381 GO:0071380 biolink:BiologicalProcess cellular response to prostaglandin E stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071380 GO:1900499 biolink:BiologicalProcess positive regulation of butyryl-CoA catabolic process to butanol Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol. go-plus.json activation of butyryl-CoA catabolic process to butanol|up-regulation of butyryl-CoA catabolic process to butanol|up regulation of butyryl-CoA catabolism to butanol|positive regulation of butyryl-CoA catabolism to butanol|activation of butyryl-CoA catabolism to butanol|up regulation of butyryl-CoA catabolic process to butanol|up-regulation of butyryl-CoA catabolism to butanol|upregulation of butyryl-CoA catabolic process to butanol|upregulation of butyryl-CoA catabolism to butanol http://purl.obolibrary.org/obo/GO_1900499 GO:1900498 biolink:BiologicalProcess negative regulation of butyryl-CoA catabolic process to butanol Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol. go-plus.json down regulation of butyryl-CoA catabolism to butanol|downregulation of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolic process to butanol|negative regulation of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolism to butanol|downregulation of butyryl-CoA catabolic process to butanol|down regulation of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolism to butanol http://purl.obolibrary.org/obo/GO_1900498 GO:1900495 biolink:BiologicalProcess negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA. go-plus.json down-regulation of butyryl-CoA biosynthesis from acetyl-CoA|down-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|negative regulation of butyryl-CoA biosynthesis from acetyl-CoA|downregulation of butyryl-CoA biosynthetic process from acetyl-CoA|downregulation of butyryl-CoA biosynthesis from acetyl-CoA|down regulation of butyryl-CoA biosynthetic process from acetyl-CoA|down regulation of butyryl-CoA biosynthesis from acetyl-CoA|inhibition of butyryl-CoA biosynthetic process from acetyl-CoA|inhibition of butyryl-CoA biosynthesis from acetyl-CoA http://purl.obolibrary.org/obo/GO_1900495 GO:1900494 biolink:BiologicalProcess regulation of butyryl-CoA biosynthetic process from acetyl-CoA Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA. go-plus.json regulation of butyryl-CoA biosynthesis from acetyl-CoA http://purl.obolibrary.org/obo/GO_1900494 GO:1900497 biolink:BiologicalProcess regulation of butyryl-CoA catabolic process to butanol Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol. go-plus.json regulation of butyryl-CoA catabolism to butanol http://purl.obolibrary.org/obo/GO_1900497 CHEBI:142396 biolink:ChemicalSubstance trans-feruloylacetyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_142396 GO:1900496 biolink:BiologicalProcess positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA. go-plus.json activation of butyryl-CoA biosynthesis from acetyl-CoA|positive regulation of butyryl-CoA biosynthesis from acetyl-CoA|up regulation of butyryl-CoA biosynthesis from acetyl-CoA|up regulation of butyryl-CoA biosynthetic process from acetyl-CoA|upregulation of butyryl-CoA biosynthetic process from acetyl-CoA|upregulation of butyryl-CoA biosynthesis from acetyl-CoA|up-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|up-regulation of butyryl-CoA biosynthesis from acetyl-CoA|activation of butyryl-CoA biosynthetic process from acetyl-CoA http://purl.obolibrary.org/obo/GO_1900496 GO:0071389 biolink:BiologicalProcess cellular response to mineralocorticoid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. go-plus.json http://purl.obolibrary.org/obo/GO_0071389 GO:0071388 biolink:BiologicalProcess cellular response to cortisone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues. go-plus.json http://purl.obolibrary.org/obo/GO_0071388 GO:0071387 biolink:BiologicalProcess cellular response to cortisol stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions. go-plus.json cellular response to hydrocortisone stimulus http://purl.obolibrary.org/obo/GO_0071387 GO:0071386 biolink:BiologicalProcess cellular response to corticosterone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses. go-plus.json http://purl.obolibrary.org/obo/GO_0071386 GO:0071374 biolink:BiologicalProcess cellular response to parathyroid hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071374 GO:0071373 biolink:BiologicalProcess cellular response to luteinizing hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071373 GO:0071372 biolink:BiologicalProcess cellular response to follicle-stimulating hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus. go-plus.json cellular response to follicle stimulating hormone stimulus|cellular response to FSH stimulus http://purl.obolibrary.org/obo/GO_0071372 GO:0071371 biolink:BiologicalProcess cellular response to gonadotropin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. go-plus.json cellular response to gonadotrophin stimulus http://purl.obolibrary.org/obo/GO_0071371 GO:0071370 biolink:BiologicalProcess cellular response to gibberellin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus. go-plus.json cellular response to gibberellic acid stimulus http://purl.obolibrary.org/obo/GO_0071370 CHEBI:142389 biolink:ChemicalSubstance trans-feruloylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142389 chebi_ph7_3 CHEBI:142384 biolink:ChemicalSubstance fatty acid 14:2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_142384 GO:0071379 biolink:BiologicalProcess cellular response to prostaglandin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071379 GO:0071378 biolink:BiologicalProcess cellular response to growth hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. go-plus.json http://purl.obolibrary.org/obo/GO_0071378 GO:0071377 biolink:BiologicalProcess cellular response to glucagon stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071377 GO:0071376 biolink:BiologicalProcess cellular response to corticotropin-releasing hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response. go-plus.json cellular response to corticotropin-releasing factor stimulus|cellular response to corticoliberin stimulus|cellular response to CRF stimulus|cellular response to CRH stimulus http://purl.obolibrary.org/obo/GO_0071376 GO:0071375 biolink:BiologicalProcess cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. go-plus.json cellular response to polypeptide hormone stimulus http://purl.obolibrary.org/obo/GO_0071375 CHEBI:142378 biolink:ChemicalSubstance ditrans,polycis-dodecaprenyl phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_142378 GO:0071396 biolink:BiologicalProcess cellular response to lipid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071396 CHEBI:142361 biolink:ChemicalSubstance purines 2'-deoxy-D-ribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_142361 chebi_ph7_3 GO:0071395 biolink:BiologicalProcess cellular response to jasmonic acid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071395 GO:0071394 biolink:BiologicalProcess cellular response to testosterone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071394 GO:0071393 biolink:BiologicalProcess cellular response to progesterone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071393 GO:0071392 biolink:BiologicalProcess cellular response to estradiol stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. go-plus.json cellular response to E2 stimulus http://purl.obolibrary.org/obo/GO_0071392 GO:0071391 biolink:BiologicalProcess cellular response to estrogen stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. go-plus.json cellular response to oestrogen stimulus http://purl.obolibrary.org/obo/GO_0071391 GO:0071390 biolink:BiologicalProcess cellular response to ecdysone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071390 GO:0071399 biolink:BiologicalProcess cellular response to linoleic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus. go-plus.json cellular response to linoleate http://purl.obolibrary.org/obo/GO_0071399 GO:0071398 biolink:BiologicalProcess cellular response to fatty acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071398 GO:0071397 biolink:BiologicalProcess cellular response to cholesterol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071397 CHEBI:142355 biolink:ChemicalSubstance purines D-ribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_142355 chebi_ph7_3 CHEBI:142345 biolink:ChemicalSubstance ditrans,polycis-dodecaprenyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142345 chebi_ph7_3 CHEBI:59198 biolink:ChemicalSubstance dichlorochromopyrrolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59198 chebi_ph7_3 CHEBI:59197 biolink:ChemicalSubstance pyrroledicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59197 CHEBI:59196 biolink:ChemicalSubstance dichlorochromopyrrolic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59196 CHEBI:59195 biolink:ChemicalSubstance 7-chloro-alpha,beta-didehydrotryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_59195 CHEBI:142348 biolink:ChemicalSubstance hexahydronaphthalenes go-plus.json http://purl.obolibrary.org/obo/CHEBI_142348 CHEBI:59194 biolink:ChemicalSubstance 2-iminio-3-(7-chloroindol-3-yl)propionate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59194 chebi_ph7_3 GO:0046327 biolink:BiologicalProcess glycerol biosynthetic process from pyruvate The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate. go-plus.json glycerol synthesis from pyruvate|glycerol formation from pyruvate|glyceroneogenesis|glycerol anabolism from pyruvate http://purl.obolibrary.org/obo/GO_0046327 GO:0046326 biolink:BiologicalProcess positive regulation of glucose import Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. go-plus.json upregulation of glucose import|stimulation of glucose import|up-regulation of glucose import|activation of glucose import|positive regulation of glucose uptake|up regulation of glucose import http://purl.obolibrary.org/obo/GO_0046326 GO:0046325 biolink:BiologicalProcess negative regulation of glucose import Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. go-plus.json downregulation of glucose import|down regulation of glucose import|inhibition of glucose import|negative regulation of glucose uptake|down-regulation of glucose import http://purl.obolibrary.org/obo/GO_0046325 GO:0046324 biolink:BiologicalProcess regulation of glucose import Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. go-plus.json regulation of glucose uptake http://purl.obolibrary.org/obo/GO_0046324 GO:0046323 biolink:BiologicalProcess glucose import The directed movement of the hexose monosaccharide glucose into a cell or organelle. Wikipedia:Glucose_uptake go-plus.json glucose uptake http://purl.obolibrary.org/obo/GO_0046323 CHEBI:60186 biolink:ChemicalSubstance EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_60186 GO:0046322 biolink:BiologicalProcess negative regulation of fatty acid oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation. go-plus.json downregulation of fatty acid oxidation|down regulation of fatty acid oxidation|inhibition of fatty acid oxidation|down-regulation of fatty acid oxidation http://purl.obolibrary.org/obo/GO_0046322 CHEBI:84149 biolink:ChemicalSubstance 4-hydroxy-6-undecylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84149 chebi_ph7_3 GO:0046321 biolink:BiologicalProcess positive regulation of fatty acid oxidation Any process that activates or increases the frequency, rate or extent of fatty acid oxidation. go-plus.json up regulation of fatty acid oxidation|upregulation of fatty acid oxidation|stimulation of fatty acid oxidation|up-regulation of fatty acid oxidation|activation of fatty acid oxidation http://purl.obolibrary.org/obo/GO_0046321 CHEBI:60187 biolink:ChemicalSubstance alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-Gal go-plus.json http://purl.obolibrary.org/obo/CHEBI_60187 chebi_ph7_3 GO:0046320 biolink:BiologicalProcess regulation of fatty acid oxidation Any process that modulates the frequency, rate or extent of fatty acid oxidation. go-plus.json http://purl.obolibrary.org/obo/GO_0046320 UBERON:0002481 biolink:AnatomicalEntity bone tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. go-plus.json portion of bone tissue|mineralized bone tissue|bone|calcium tissue|osteogenic tissue|osseous tissue http://purl.obolibrary.org/obo/UBERON_0002481 GO:0061960 biolink:BiologicalProcess regulation of heme oxygenase activity Any process that modulates the frequency, or rate of heme oxygenase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061960 CHEBI:84146 biolink:ChemicalSubstance 3beta-hydroxycholest-5-en-26-oate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84146 chebi_ph7_3 CHEBI:60189 biolink:ChemicalSubstance 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60189 chebi_ph7_3 CHEBI:84145 biolink:ChemicalSubstance 3beta-hydroxycholest-5-en-26-al go-plus.json http://purl.obolibrary.org/obo/CHEBI_84145 chebi_ph7_3 UBERON:0002483 biolink:AnatomicalEntity trabecular bone tissue bone tissue that has a lattice-like or spongy structure; it is highly vascular and contains intercommunicating spaces filled with bone marrow go-plus.json cancellous bone|trabecular bone|substantia spongiosa|substantia trabecularis ossium|cancellous bone tissue|cancellated bone|spongy bone|substantia spongiosa ossium|substantia trabecularis|trabecular substance|spongy bone tissue http://purl.obolibrary.org/obo/UBERON_0002483 GO:0061962 biolink:BiologicalProcess negative regulation of heme oxygenase activity Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061962 CHEBI:84144 biolink:ChemicalSubstance L-phenylalanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84144 UBERON:0002482 biolink:AnatomicalEntity lamellar bone Bone tissue that has a regular parallel alignment of collagen into sheets (lamellae) and is mechanically strong. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002482 CL:0002145 biolink:Cell ciliated columnar cell of tracheobronchial tree A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree. go-plus.json http://purl.obolibrary.org/obo/CL_0002145 GO:0061961 biolink:BiologicalProcess positive regulation of heme oxygenase activity Any process that activates or increases the frequency or rate of heme oxygenase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0061961 CHEBI:84143 biolink:ChemicalSubstance D-phenylalanine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84143 GO:0061964 biolink:BiologicalProcess negative regulation of entry into reproductive diapause Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0061964 CHEBI:84142 biolink:ChemicalSubstance 1D-myo-inositol 2-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84142 chebi_ph7_3 GO:0061963 biolink:BiologicalProcess regulation of entry into reproductive diapause Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0061963 CHEBI:84141 biolink:ChemicalSubstance 1D-myo-inositol 5-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84141 chebi_ph7_3 GO:0046329 biolink:BiologicalProcess negative regulation of JNK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade. go-plus.json down regulation of JNK cascade|downregulation of JNK cascade|down-regulation of JNK cascade|inhibition of JNK cascade http://purl.obolibrary.org/obo/GO_0046329 GO:0061966 biolink:BiologicalProcess establishment of left/right asymmetry The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0061966 CHEBI:84140 biolink:ChemicalSubstance myo-inositol monophosphate derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84140 GO:0061965 biolink:BiologicalProcess positive regulation of entry into reproductive diapause Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0061965 CL:0002149 biolink:Cell epithelial cell of uterus An epithelial cell of the uterus. go-plus.json http://purl.obolibrary.org/obo/CL_0002149 GO:0046328 biolink:BiologicalProcess regulation of JNK cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade. go-plus.json regulation of SAPK cascade http://purl.obolibrary.org/obo/GO_0046328 GO:0061968 biolink:BiologicalProcess maintenance of left/right asymmetry The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0061968 UBERON:0002489 biolink:AnatomicalEntity coronal suture the dense, fibrous connective tissue joint between the tetrapod parietal bones and the frontal bone go-plus.json frontoparietal suture|coronal suture of skull|fronto-parietal suture|sutura coronalis http://purl.obolibrary.org/obo/UBERON_0002489 GO:0061967 biolink:BiologicalProcess establishment of left sidedness The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side. go-plus.json http://purl.obolibrary.org/obo/GO_0061967 GO:0061969 biolink:BiologicalProcess maintenance of left sidedness The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0061969 CHEBI:25858 biolink:ChemicalSubstance 1,7-dimethylxanthine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25858 chebi_ph7_3 UBERON:0002485 biolink:AnatomicalEntity prostate duct The minute canals that pass the prostatic secretions to the urethra. go-plus.json duct of prostate|prostate gland duct|prostatic duct|duct of prostate gland|prostate duct http://purl.obolibrary.org/obo/UBERON_0002485 CL:0002140 biolink:Cell acinar cell of sebaceous gland A sebum secreting cell of the skin that secretes sebum into the hair follicles. go-plus.json sebocyte http://purl.obolibrary.org/obo/CL_0002140 SO:0001645 biolink:SequenceFeature genetic_marker A measurable sequence feature that varies within a population. go-plus.json genetic marker http://purl.obolibrary.org/obo/SO_0001645 GO:0046330 biolink:BiologicalProcess positive regulation of JNK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade. go-plus.json up-regulation of JNK cascade|upregulation of JNK cascade|up regulation of JNK cascade|activation of JNK cascade|stimulation of JNK cascade http://purl.obolibrary.org/obo/GO_0046330 GO:1900408 biolink:BiologicalProcess negative regulation of cellular response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress. go-plus.json downregulation of cellular response to oxidative stress|down regulation of adaptive response to oxidative stress|downregulation of adaptive response to oxidative stress|down-regulation of cellular response to oxidative stress|negative regulation of adaptive response to oxidative stress|down-regulation of adaptive response to oxidative stress|inhibition of cellular response to oxidative stress|inhibition of adaptive response to oxidative stress|down regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1900408 GO:1900407 biolink:BiologicalProcess regulation of cellular response to oxidative stress Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. go-plus.json regulation of adaptive response to oxidative stress http://purl.obolibrary.org/obo/GO_1900407 CHEBI:25863 biolink:ChemicalSubstance pelargonidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_25863 OBO:GOCHE_38231 biolink:OntologyClass substance with phytotoxin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_38231 3_STAR OBO:GOCHE_38234 biolink:OntologyClass substance with DNA polymerase inhibitor role go-plus.json http://purl.obolibrary.org/obo/GOCHE_38234 3_STAR GO:1900409 biolink:BiologicalProcess positive regulation of cellular response to oxidative stress Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress. go-plus.json upregulation of adaptive response to oxidative stress|up regulation of cellular response to oxidative stress|activation of cellular response to oxidative stress|up regulation of adaptive response to oxidative stress|positive regulation of adaptive response to oxidative stress|up-regulation of cellular response to oxidative stress|activation of adaptive response to oxidative stress|up-regulation of adaptive response to oxidative stress|upregulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1900409 GO:1900404 biolink:BiologicalProcess positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair. go-plus.json up regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|upregulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|stimulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|up-regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|activation of DNA repair by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900404 GO:1900403 biolink:BiologicalProcess obsolete negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cellular amino acid biosynthetic process. go-plus.json negative regulation of cellular amino acid biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid formation by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900403 CHEBI:60191 biolink:ChemicalSubstance rhamnogalacturonan II go-plus.json http://purl.obolibrary.org/obo/CHEBI_60191 GO:1900406 biolink:BiologicalProcess obsolete regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_1900406 CHEBI:60190 biolink:ChemicalSubstance homogalacturonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_60190 CHEBI:25865 biolink:ChemicalSubstance penicillanic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_25865 GO:1900405 biolink:BiologicalProcess obsolete regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cell separation after cytokinesis. go-plus.json regulation of cytokinetic cell separation by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900405 GO:0046338 biolink:BiologicalProcess phosphatidylethanolamine catabolic process The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. go-plus.json phosphatidylethanolamine degradation|phosphatidylethanolamine catabolism|phosphatidylethanolamine breakdown http://purl.obolibrary.org/obo/GO_0046338 GO:1900400 biolink:BiologicalProcess regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion import. go-plus.json regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter|regulation of iron import by regulation of transcription from RNA polymerase II promoter|regulation of iron ion import by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900400 CHEBI:60193 biolink:ChemicalSubstance queuosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60193 CHEBI:60192 biolink:ChemicalSubstance triacyl lipopeptide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60192 GO:0046337 biolink:BiologicalProcess phosphatidylethanolamine metabolic process The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes. go-plus.json phosphatidylethanolamine metabolism http://purl.obolibrary.org/obo/GO_0046337 GO:1900402 biolink:BiologicalProcess obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process. go-plus.json regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900402 GO:0046336 biolink:BiologicalProcess ethanolamine catabolic process The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). go-plus.json ethanolamine degradation|ethanolamine breakdown|ethanolamine catabolism http://purl.obolibrary.org/obo/GO_0046336 CHEBI:60195 biolink:ChemicalSubstance cyclic peptide cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60195 GO:0046335 biolink:BiologicalProcess ethanolamine biosynthetic process The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). go-plus.json ethanolamine biosynthesis|ethanolamine anabolism|ethanolamine synthesis|ethanolamine formation http://purl.obolibrary.org/obo/GO_0046335 GO:1900401 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900401 CHEBI:60194 biolink:ChemicalSubstance peptide cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60194 GO:0046334 biolink:BiologicalProcess octopamine catabolic process The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. go-plus.json octopamine degradation|octopamine breakdown|octopamine catabolism http://purl.obolibrary.org/obo/GO_0046334 CHEBI:60197 biolink:ChemicalSubstance bacteriochlorophyll c go-plus.json http://purl.obolibrary.org/obo/CHEBI_60197 GO:0046333 biolink:BiologicalProcess octopamine metabolic process The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. go-plus.json octopamine metabolism http://purl.obolibrary.org/obo/GO_0046333 CHEBI:60196 biolink:ChemicalSubstance O-phospho peptide cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60196 CHEBI:60199 biolink:ChemicalSubstance acyl monophosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60199 GO:0046332 biolink:MolecularActivity SMAD binding Binding to a SMAD signaling protein. go-plus.json http://purl.obolibrary.org/obo/GO_0046332 GO:0046331 biolink:BiologicalProcess lateral inhibition Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells. go-plus.json http://purl.obolibrary.org/obo/GO_0046331 UBERON:0002470 biolink:AnatomicalEntity autopod region Terminal segment of free limb, immediately distal to the zeugopod region. The fully developed autopod consists of the autopod skeleton plus associated structures such as integument, muscle tissue, vasculature etc. The autopod is divided into mesopodial, metapodiual, and acropodial segments. Examples: human hand, mouse paw, human foot go-plus.json distal segment of limb|distal segment of free limb|autopodial element|autopodial segment|autopod|autopodium|distal free limb segment|autopodium region|autopodial limb segment|paw/hand/foot/hoof|manus/pes|paw|pod http://purl.obolibrary.org/obo/UBERON_0002470 GO:0061951 biolink:BiologicalProcess establishment of protein localization to plasma membrane The directed movement of a protein to a specific location in a plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0061951 UBERON:0002472 biolink:AnatomicalEntity stylopod The proximal free limb segment. Includes as parts the stylopod skeleton. go-plus.json stylopodial limb segment|stylopodium|proximal free limb segment|proximal segment of free limb|propodium|proximal part of limb http://purl.obolibrary.org/obo/UBERON_0002472 UBERON:0002471 biolink:AnatomicalEntity zeugopod The middle free limb segment, between the autopod and stylopod segments. Includes as parts the zeugopodial skeleton. Examples: There are two types of zeugopod: forelimb zeugopod (aka forearm), hindlimb zeugopod (aka crus). go-plus.json zygopod|epipodium|zeugopod limb segment|middle segment of free limb|middle limb segment|middle part of limb|middle free limb segment|zeugopodium|zeugopodial limb segment|zygopodium http://purl.obolibrary.org/obo/UBERON_0002471 GO:0061950 biolink:BiologicalProcess negative regulation of premature acrosome loss Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents. go-plus.json negative regulation of spontaneous acrosome loss http://purl.obolibrary.org/obo/GO_0061950 CHEBI:84153 biolink:ChemicalSubstance 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84153 GO:0061953 biolink:MolecularActivity mRNA (adenine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0061953 CL:0002159 biolink:Cell general ecto-epithelial cell Epithelial cells derived from general body ectoderm and ectoderm placodes. go-plus.json http://purl.obolibrary.org/obo/CL_0002159 GO:0061952 biolink:BiologicalProcess midbody abscission The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells. go-plus.json cell separation during cytokinesis|cytokinetic abscission http://purl.obolibrary.org/obo/GO_0061952 GO:0061955 biolink:BiologicalProcess positive regulation of actin filament depolymerization involved in acrosome reaction Any process that increases the rate or exent of actin depolymerization as part of the acrosome reaction. This allows the acrosomal membrane and plasma membrane to fuse. go-plus.json http://purl.obolibrary.org/obo/GO_0061955 GO:0046339 biolink:BiologicalProcess diacylglycerol metabolic process The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. go-plus.json diacylglycerol metabolism|diglyceride metabolism http://purl.obolibrary.org/obo/GO_0046339 GO:0061954 biolink:BiologicalProcess positive regulation of actin filament polymerization involved in sperm capacitation Any process that icreases the rate or extent of actin polymerization as part of sperm capacitation. This process prevents a spontaneous acrosome reaction. go-plus.json http://purl.obolibrary.org/obo/GO_0061954 CHEBI:84150 biolink:ChemicalSubstance 4-hydroxy-6-(2-oxotridecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84150 chebi_ph7_3 UBERON:0002478 biolink:AnatomicalEntity orbitosphenoid the bone that is situated in the orbit on either side of the presphenoid; it generally forms a part of the sphenoid in the adult, and may be independent in the young go-plus.json lesser wing of sphenoid bone|lesser wing of sphenoidal bone|orbitosphenoids|ala minor (os sphenoidale)|orbitosphenoid bone|ala minor ossis sphenoidalis|alae parvae|ingrassia's process|lesser wing of sphenoid http://purl.obolibrary.org/obo/UBERON_0002478 GO:0061957 biolink:CellularComponent NVT complex A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1. go-plus.json http://purl.obolibrary.org/obo/GO_0061957 GO:0061956 biolink:BiologicalProcess penetration of cumulus oophorus The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm. go-plus.json penetration of cumulus mass|penetration of cumulus cells layer http://purl.obolibrary.org/obo/GO_0061956 GO:0061959 biolink:BiologicalProcess response to (R)-carnitine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus. go-plus.json response to L-carnitine http://purl.obolibrary.org/obo/GO_0061959 NCBITaxon:32033 biolink:OrganismalEntity Xanthomonadaceae go-plus.json Xanthomonas group|Lysobacteraceae http://purl.obolibrary.org/obo/NCBITaxon_32033 UBERON:0002473 biolink:AnatomicalEntity intercerebral commissure A commissure that connects the two cerebral hemispheres. Examples: anterior commissure, corpus callosum. go-plus.json inter-hemispheric commissure|commissure of cerebrum|interhemispheric commissure http://purl.obolibrary.org/obo/UBERON_0002473 CL:0002153 biolink:Cell corneocyte The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus. go-plus.json http://purl.obolibrary.org/obo/CL_0002153 GO:0046341 biolink:BiologicalProcess CDP-diacylglycerol metabolic process The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis. go-plus.json CDP-diacylglycerol metabolism http://purl.obolibrary.org/obo/GO_0046341 GO:1900419 biolink:BiologicalProcess regulation of cellular alcohol catabolic process Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process. go-plus.json http://purl.obolibrary.org/obo/GO_1900419 GO:0046340 biolink:BiologicalProcess diacylglycerol catabolic process The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. go-plus.json diglyceride catabolism|diacylglycerol catabolism|diacylglycerol degradation|diacylglycerol breakdown http://purl.obolibrary.org/obo/GO_0046340 GO:1900418 biolink:BiologicalProcess obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process. go-plus.json upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900418 CHEBI:25830 biolink:ChemicalSubstance p-quinones go-plus.json http://purl.obolibrary.org/obo/CHEBI_25830 GO:1900415 biolink:BiologicalProcess obsolete regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of fungal-type cell wall biogenesis. go-plus.json regulation of chitin- and beta-glucan-containing cell wall biogenesis by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900415 CHEBI:25835 biolink:ChemicalSubstance hexadecanoate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_25835 chebi_ph7_3 GO:1900414 biolink:BiologicalProcess obsolete regulation of cytokinesis by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_1900414 GO:1900417 biolink:BiologicalProcess obsolete negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of transmembrane transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900417 GO:1900416 biolink:BiologicalProcess obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of 4,6-pyruvylated galactose residue biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_1900416 GO:0046349 biolink:BiologicalProcess amino sugar biosynthetic process The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group. go-plus.json amino sugar synthesis|amino sugar formation|amino sugar biosynthesis|aminosaccharide biosynthesis|aminosaccharide biosynthetic process|amino sugar anabolism http://purl.obolibrary.org/obo/GO_0046349 GO:1900411 biolink:BiologicalProcess obsolete regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone acetylation. go-plus.json http://purl.obolibrary.org/obo/GO_1900411 CL:0002129 biolink:Cell regular atrial cardiac myocyte Regular cardiac myocyte of a cardiac atrium. go-plus.json atrial cardiac muscle cell|atrial myocyte|regular cardiac muscle cell of atrium|regular atrial cardiac muscle fiber http://purl.obolibrary.org/obo/CL_0002129 GO:1900410 biolink:BiologicalProcess obsolete regulation of histone modification by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone modification. go-plus.json http://purl.obolibrary.org/obo/GO_1900410 GO:0046348 biolink:BiologicalProcess amino sugar catabolic process The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group. go-plus.json amino sugar catabolism|aminosaccharide catabolic process|amino sugar degradation|amino sugar breakdown|aminosaccharide catabolism http://purl.obolibrary.org/obo/GO_0046348 GO:1900413 biolink:BiologicalProcess obsolete positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process. go-plus.json positive regulation of phospholipid biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phospholipid synthesis by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900413 GO:0046347 biolink:BiologicalProcess mannosamine biosynthetic process The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins. go-plus.json mannosamine anabolism|mannosamine synthesis|mannosamine biosynthesis|mannosamine formation http://purl.obolibrary.org/obo/GO_0046347 GO:0046346 biolink:BiologicalProcess mannosamine catabolic process The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins. go-plus.json mannosamine degradation|mannosamine breakdown|mannosamine catabolism http://purl.obolibrary.org/obo/GO_0046346 GO:1900412 biolink:BiologicalProcess obsolete regulation of histone methylation by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone methylation. go-plus.json http://purl.obolibrary.org/obo/GO_1900412 GO:0046345 biolink:BiologicalProcess abscisic acid catabolic process The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. go-plus.json abscisic acid breakdown|abscisic acid catabolism|abscisic acid degradation http://purl.obolibrary.org/obo/GO_0046345 GO:0046344 biolink:BiologicalProcess ecdysteroid catabolic process The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. go-plus.json ecdysteroid catabolism|ecdysteroid degradation|ecdysteroid breakdown http://purl.obolibrary.org/obo/GO_0046344 GO:0061980 biolink:MolecularActivity regulatory RNA binding Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0061980 GO:0046343 biolink:BiologicalProcess streptomycin metabolic process The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. go-plus.json streptomycin metabolism http://purl.obolibrary.org/obo/GO_0046343 GO:0046342 biolink:BiologicalProcess CDP-diacylglycerol catabolic process The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. go-plus.json CDP-diacylglycerol catabolism|CDP-diacylglycerol degradation|CDP-diacylglycerol breakdown http://purl.obolibrary.org/obo/GO_0046342 CHEBI:84169 biolink:ChemicalSubstance 4-hydroxy-6-heptadecylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84169 chebi_ph7_3 GO:0061982 biolink:BiologicalProcess meiosis I cell cycle process A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs. go-plus.json first meiotic cell division http://purl.obolibrary.org/obo/GO_0061982 CL:0002122 biolink:Cell B220-positive CD38-positive IgG-negative class switched memory B cell A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002122 CHEBI:84168 biolink:ChemicalSubstance 4-hydroxy-6-pentadecylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84168 chebi_ph7_3 CHEBI:11222 biolink:ChemicalSubstance 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_11222 chebi_ph7_3 CL:0002121 biolink:Cell CD24-negative CD38-negative IgG-negative class switched memory B cell A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002121 GO:0061981 biolink:MolecularActivity 3-hydroxykynureninase activity Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. RHEA:25143 go-plus.json http://purl.obolibrary.org/obo/GO_0061981 CHEBI:84167 biolink:ChemicalSubstance 2-methoxy-3-methyl-6-all-trans-polyprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84167 chebi_ph7_3 CL:0002124 biolink:Cell CD27-positive gamma-delta T cell A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. go-plus.json gd27-positive|gammadelta27-positive http://purl.obolibrary.org/obo/CL_0002124 CHEBI:84166 biolink:ChemicalSubstance 2-methoxy-6-all-trans-polyprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84166 chebi_ph7_3 GO:0061984 biolink:BiologicalProcess catabolite repression A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources. go-plus.json http://purl.obolibrary.org/obo/GO_0061984 UBERON:0002460 biolink:AnatomicalEntity vesical vein A tributary of the iliac vein that drains the urinary bladder. go-plus.json vesical veins set|vesical veins|venae vesicales http://purl.obolibrary.org/obo/UBERON_0002460 CL:0002123 biolink:Cell B220-low CD38-positive IgG-negative class switched memory B cell A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002123 GO:0061983 biolink:BiologicalProcess meiosis II cell cycle process A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. go-plus.json second meiotic division http://purl.obolibrary.org/obo/GO_0061983 GO:0061986 biolink:BiologicalProcess negative regulation of transcription by glucose Any process involving glucose that decreases the frequency, rate or extent or transcription. go-plus.json http://purl.obolibrary.org/obo/GO_0061986 GO:0071309 biolink:BiologicalProcess cellular response to phylloquinone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus. go-plus.json cellular response to vitamin K1 http://purl.obolibrary.org/obo/GO_0071309 CL:0002126 biolink:Cell CD25-positive, CD27-positive immature gamma-delta T cell A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). go-plus.json http://purl.obolibrary.org/obo/CL_0002126 GO:0071308 biolink:BiologicalProcess cellular response to menaquinone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus. go-plus.json cellular response to vitamin K2|cellular response to menatetrenone http://purl.obolibrary.org/obo/GO_0071308 GO:0061985 biolink:BiologicalProcess carbon catabolite repression A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources. go-plus.json http://purl.obolibrary.org/obo/GO_0061985 CL:0002125 biolink:Cell CD27-negative gamma-delta T cell A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion. go-plus.json gammadelta-17 cells http://purl.obolibrary.org/obo/CL_0002125 CHEBI:84163 biolink:ChemicalSubstance anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) betaine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84163 chebi_ph7_3 GO:0071307 biolink:BiologicalProcess cellular response to vitamin K Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071307 CHEBI:84162 biolink:ChemicalSubstance (2E,6E)-farnesoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84162 GO:0061988 biolink:BiologicalProcess karyosome formation The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061988 CL:0002127 biolink:Cell innate effector T cell A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation. go-plus.json http://purl.obolibrary.org/obo/CL_0002127 GO:0071306 biolink:BiologicalProcess cellular response to vitamin E Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus. go-plus.json cellular response to O-Acetyl-alpha-tocopherol|cellular response to DL-alpha-tocopherol acetate|cellular response to DL-alpha-tocopheryl acetate http://purl.obolibrary.org/obo/GO_0071306 GO:0061987 biolink:BiologicalProcess negative regulation of transcription from RNA polymerase II promoter by glucose Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_0061987 GO:0071305 biolink:BiologicalProcess cellular response to vitamin D Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus. go-plus.json cellular response to calciferol|cellular response to ergocalciferol|cellular response to cholecalciferol http://purl.obolibrary.org/obo/GO_0071305 SO:0001669 biolink:SequenceFeature RNApol_II_core_promoter The minimal portion of the promoter required to properly initiate transcription in RNA polymerase II transcribed genes. go-plus.json RNApol II core promoter http://purl.obolibrary.org/obo/SO_0001669 UBERON:0002466 biolink:AnatomicalEntity intestine secretion Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine. go-plus.json succus entericus|intestinal juice|intestinal secretion http://purl.obolibrary.org/obo/UBERON_0002466 GO:0071304 biolink:BiologicalProcess cellular response to vitamin B6 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0071304 GO:0061989 biolink:BiologicalProcess sperm karyosome formation The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome. go-plus.json http://purl.obolibrary.org/obo/GO_0061989 CHEBI:25838 biolink:ChemicalSubstance palmitoyl amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25838 UBERON:0002469 biolink:AnatomicalEntity esophagus mucosa A mucosa that is part of a esophagus [Automatically generated definition]. go-plus.json oesophagus mucosa|mucous membrane of esophagus|esophageal mucous membrane|mucosa of esophagus|esophageal mucosa|oesophagus mucous membrane|esophagus mucosa|tunica mucosa esophagi|oesophageal mucosa|lamina muscularis mucosae oesophageae|tunica mucosa oesophagi|tunica mucosa oesophageae|muscularis mucosae of oesophagus|esophagus mucous membrane|tunica mucosa oesophagi|mucosa of oesophagus|mucous membrane of oesophagus http://purl.obolibrary.org/obo/UBERON_0002469 GO:0071303 biolink:BiologicalProcess cellular response to vitamin B3 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus. go-plus.json cellular response to nicotinamide|cellular response to niacin http://purl.obolibrary.org/obo/GO_0071303 GO:0071302 biolink:BiologicalProcess cellular response to vitamin B2 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus. go-plus.json cellular response to riboflavin http://purl.obolibrary.org/obo/GO_0071302 CHEBI:49807 biolink:ChemicalSubstance lead(2+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49807 chebi_ph7_3 GO:0071301 biolink:BiologicalProcess cellular response to vitamin B1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus. go-plus.json cellular response to thiamin|cellular response to thiamine http://purl.obolibrary.org/obo/GO_0071301 GO:0071300 biolink:BiologicalProcess cellular response to retinoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. go-plus.json cellular response to vitamin A acid http://purl.obolibrary.org/obo/GO_0071300 UBERON:0002465 biolink:AnatomicalEntity lymphoid system The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system[WP]. go-plus.json lymphatic circulatory system|lymphatic system|lymphatic drainage system|systema lymphoideum http://purl.obolibrary.org/obo/UBERON_0002465 CL:0002120 biolink:Cell CD24-positive CD38-negative IgG-negative class switched memory B cell An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002120 UBERON:0002464 biolink:AnatomicalEntity nerve trunk go-plus.json trunk of nerve|trunk of peripheral nerve|peripheral nerve trunk http://purl.obolibrary.org/obo/UBERON_0002464 CHEBI:25842 biolink:ChemicalSubstance palmityl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_25842 chebi_ph7_3 GO:0046352 biolink:BiologicalProcess disaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units. go-plus.json disaccharide catabolism|disaccharide degradation|disaccharide breakdown http://purl.obolibrary.org/obo/GO_0046352 GO:0046351 biolink:BiologicalProcess disaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units. go-plus.json disaccharide formation|disaccharide biosynthesis|disaccharide anabolism|disaccharide synthesis http://purl.obolibrary.org/obo/GO_0046351 GO:1900429 biolink:BiologicalProcess negative regulation of filamentous growth of a population of unicellular organisms Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms. go-plus.json downregulation of filamentous growth of a population of unicellular organisms|down-regulation of filamentous growth of a population of unicellular organisms|inhibition of filamentous growth of a population of unicellular organisms|down regulation of filamentous growth of a population of unicellular organisms http://purl.obolibrary.org/obo/GO_1900429 CHEBI:25840 biolink:ChemicalSubstance palmitoyl-L-cysteine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25840 GO:0046350 biolink:BiologicalProcess galactosaminoglycan metabolic process The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose. go-plus.json galactosaminoglycan metabolism http://purl.obolibrary.org/obo/GO_0046350 GO:1900426 biolink:BiologicalProcess positive regulation of defense response to bacterium Any process that activates or increases the frequency, rate or extent of defense response to bacterium. go-plus.json upregulation of defence response to bacteria|up-regulation of defense response to bacterium|activation of resistance response to pathogenic bacterium|positive regulation of defense response to bacterium, incompatible interaction|up regulation of defence response to bacterium|positive regulation of defense response to bacteria|positive regulation of defence response to bacterium|upregulation of antibacterial peptide activity|up regulation of defense response to bacteria|upregulation of defense response to bacterium|up-regulation of defence response to bacteria|activation of defence response to bacterium|activation of resistance response to pathogenic bacteria|up-regulation of antibacterial peptide activity|activation of defence response to bacteria|up-regulation of defence response to bacterium|upregulation of defense response to bacteria|up regulation of defense response to bacterium|positive regulation of defence response to bacteria|activation of defense response to bacterium|activation of antibacterial peptide activity|up regulation of defence response to bacteria|upregulation of defence response to bacterium|up-regulation of defense response to bacteria|positive regulation of antibacterial peptide activity|up regulation of antibacterial peptide activity|activation of defense response to bacteria http://purl.obolibrary.org/obo/GO_1900426 GO:1900425 biolink:BiologicalProcess negative regulation of defense response to bacterium Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. go-plus.json inhibition of defense response to bacterium, incompatible interaction|inhibition of resistance response to pathogenic bacteria|inhibition of response to pathogenic bacteria (incompatible interaction)|down regulation of antibacterial peptide activity|inhibition of defence response to bacteria|negative regulation of defense response to bacterium, incompatible interaction|down-regulation of defence response to bacterium|negative regulation of defence response to bacterium|downregulation of defense response to bacteria|inhibition of antibacterial peptide activity|down regulation of defense response to bacterium|down regulation of defense response to bacteria|inhibition of resistance response to pathogenic bacterium|negative regulation of defence response to bacteria|down-regulation of defence response to bacteria|downregulation of defense response to bacterium|inhibition of defence response to pathogenic bacterium, incompatible interaction|inhibition of response to pathogenic bacterium (incompatible interaction)|inhibition of defense response to bacteria|inhibition of defence response to bacterium|down-regulation of antibacterial peptide activity|negative regulation of antibacterial peptide activity|downregulation of defence response to bacteria|down-regulation of defense response to bacterium|down regulation of defence response to bacterium|down regulation of defence response to bacteria|downregulation of defence response to bacterium|downregulation of antibacterial peptide activity|negative regulation of defense response to bacteria|down-regulation of defense response to bacteria|inhibition of defense response to bacterium|inhibition of defence response to pathogenic bacteria, incompatible interaction http://purl.obolibrary.org/obo/GO_1900425 CHEBI:25845 biolink:ChemicalSubstance pantetheines go-plus.json http://purl.obolibrary.org/obo/CHEBI_25845 UBERON:0002448 biolink:AnatomicalEntity fungiform papilla Any of the mushroom-shaped papillae, which have a single taste bud at the tip, located mostly on the dorsal anterior portion of the tongue go-plus.json fungiform papillae set|fungiform papillae|fungiform papilla of tongue|papillae fungiformes http://purl.obolibrary.org/obo/UBERON_0002448 GO:1900428 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms. go-plus.json http://purl.obolibrary.org/obo/GO_1900428 GO:1900427 biolink:BiologicalProcess obsolete regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress. go-plus.json regulation of adaptive response to oxidative stress by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900427 GO:1900422 biolink:BiologicalProcess obsolete positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of cellular alcohol catabolic process. go-plus.json up regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|activation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900422 GO:0046359 biolink:BiologicalProcess butyrate catabolic process The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid. go-plus.json butyrate breakdown|butyrate catabolism|butanoic acid catabolism|butanoic acid degradation|butanoic acid breakdown|butanoic acid catabolic process|butyrate degradation http://purl.obolibrary.org/obo/GO_0046359 GO:1900421 biolink:BiologicalProcess positive regulation of cellular alcohol catabolic process Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process. go-plus.json up regulation of cellular alcohol catabolic process|upregulation of cellular alcohol catabolic process|up-regulation of cellular alcohol catabolic process|activation of cellular alcohol catabolic process http://purl.obolibrary.org/obo/GO_1900421 PR:000021003 biolink:Protein urokinase-type plasminogen activator proteolytic cleavage product A urokinase-type plasminogen activator that has been processed by proteolytic cleavage. go-plus.json PLAU/ClvPrd http://purl.obolibrary.org/obo/PR_000021003 GO:1900424 biolink:BiologicalProcess regulation of defense response to bacterium Any process that modulates the frequency, rate or extent of defense response to bacterium. go-plus.json regulation of antibacterial peptide activity|regulation of defence response to pathogenic bacterium, incompatible interaction|regulation of defence response to pathogenic bacteria, incompatible interaction|regulation of defense response to bacteria|regulation of resistance response to pathogenic bacterium|regulation of resistance response to pathogenic bacteria|regulation of defence response to bacterium, incompatible interaction|regulation of defense response to bacterium, incompatible interaction|regulation of defence response to bacteria|regulation of defence response to bacterium http://purl.obolibrary.org/obo/GO_1900424 GO:0046358 biolink:BiologicalProcess butyrate biosynthetic process The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid. go-plus.json butanoic acid synthesis|butyrate biosynthesis|butanoic acid formation|butyrate anabolism|butyrate synthesis|butanoic acid biosynthetic process|butanoic acid biosynthesis|butyrate formation|butanoic acid anabolism http://purl.obolibrary.org/obo/GO_0046358 GO:1900423 biolink:BiologicalProcess obsolete positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching. go-plus.json up regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|activation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|stimulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|upregulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900423 GO:0046357 biolink:BiologicalProcess galactarate biosynthetic process The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid. go-plus.json galactarate synthesis|galactarate formation|D-galactarate biosynthesis|D-galactarate biosynthetic process|galactarate biosynthesis|D-galactarate anabolism|D-galactarate synthesis|D-galactarate formation|galactarate anabolism http://purl.obolibrary.org/obo/GO_0046357 GO:0046356 biolink:BiologicalProcess acetyl-CoA catabolic process The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. go-plus.json acetyl-CoA degradation|acetyl-CoA breakdown|acetyl-CoA catabolism http://purl.obolibrary.org/obo/GO_0046356 GO:0046355 biolink:BiologicalProcess mannan catabolic process The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose. go-plus.json mannan catabolism|mannan degradation|mannan breakdown http://purl.obolibrary.org/obo/GO_0046355 GO:0046354 biolink:BiologicalProcess mannan biosynthetic process The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose. go-plus.json mannan synthesis|mannan formation|mannan biosynthesis|mannan anabolism http://purl.obolibrary.org/obo/GO_0046354 GO:1900420 biolink:BiologicalProcess negative regulation of cellular alcohol catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process. go-plus.json down-regulation of cellular alcohol catabolic process|downregulation of cellular alcohol catabolic process|down regulation of cellular alcohol catabolic process|inhibition of cellular alcohol catabolic process http://purl.obolibrary.org/obo/GO_1900420 GO:0046353 biolink:MolecularActivity aminoglycoside 3-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring. EC:2.3.1.60|EC:2.3.1.81|MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN|MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN go-plus.json acetyl-CoA:gentamicin-C N3'-acetyltransferase activity|gentamycin acetyltransferase I|gentamicin-(3)-N-acetyltransferase activity|aminoglycoside acetyltransferase AAC(3)-1|gentamycin 3'-N-acetyltransferase activity|gentamicin acetyltransferase I activity|3-N-aminoglycoside acetyltransferase activity|3'-aminoglycoside acetyltransferase activity|acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity|aminoglycoside acetyltransferase AAC(3)-I activity|gentamicin 3'-N-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0046353 GO:0061971 biolink:BiologicalProcess replacement bone morphogenesis The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. go-plus.json http://purl.obolibrary.org/obo/GO_0061971 GO:0061970 biolink:BiologicalProcess maintenance of right sidedness The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves. go-plus.json http://purl.obolibrary.org/obo/GO_0061970 CL:0002132 biolink:Cell stromal cell of ovary A stomal cell of the ovary go-plus.json ovarian stromal cell http://purl.obolibrary.org/obo/CL_0002132 UBERON:0002450 biolink:AnatomicalEntity decidua The maternal uterine-derived portion of the placenta go-plus.json maternal decidual layer|maternal placenta|decidous membrane|extraembryonic part of placenta|maternal part of placenta|uterine decidua|placenta maternal decidual layer|endometrium|decidua basalis|extraembryonic placenta http://purl.obolibrary.org/obo/UBERON_0002450 GO:0061973 biolink:BiologicalProcess membrane bone morphogenesis The process in which bone which forms deep in the organism are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061973 CHEBI:84177 biolink:ChemicalSubstance 14-HPDHE go-plus.json http://purl.obolibrary.org/obo/CHEBI_84177 GO:0061972 biolink:BiologicalProcess dermal bone morphogenesis The process in which bone which forms superficially in the organism are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0061972 CHEBI:84176 biolink:ChemicalSubstance 12-methyloctadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84176 chebi_ph7_3 GO:0061975 biolink:BiologicalProcess articular cartilage development The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure. go-plus.json articular cartilage of joint development http://purl.obolibrary.org/obo/GO_0061975 CHEBI:84175 biolink:ChemicalSubstance 2-methylhexadecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84175 chebi_ph7_3 GO:0061974 biolink:BiologicalProcess perichondral bone morphogenesis The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone. go-plus.json http://purl.obolibrary.org/obo/GO_0061974 CHEBI:84174 biolink:ChemicalSubstance 12-HPE(8,10,14)TrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_84174 GO:0061977 biolink:BiologicalProcess hip joint articular cartilage development The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061977 CL:0002139 biolink:Cell endothelial cell of vascular tree An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. go-plus.json cubodial endothelial cell of vascular tree|vascular endothelial cell http://purl.obolibrary.org/obo/CL_0002139 CHEBI:84173 biolink:ChemicalSubstance 4-hydroxy-6-(2-oxohenicosyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84173 chebi_ph7_3 GO:0061976 biolink:BiologicalProcess temporomandibular joint articular cartilage development The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061976 CL:0002138 biolink:Cell endothelial cell of lymphatic vessel A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. go-plus.json LEC|lymphatic endothelial cell http://purl.obolibrary.org/obo/CL_0002138 CHEBI:84172 biolink:ChemicalSubstance 4-hydroxy-6-(2-oxononadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84172 chebi_ph7_3 GO:0061979 biolink:BiologicalProcess femoral head articular cartilage development The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061979 UBERON:0002456 biolink:AnatomicalEntity internal thoracic artery An artery that supplies the anterior chest wall and the breasts. It is a paired artery, with one running along each side of the sternum, to continue after its bifurcation as the superior epigastric and musculophrenic arteries. [WP,unvetted]. go-plus.json arteria thoracica interna|internal thoracic mammary artery|arteria mammaria interna|internal mammary artery|mammary artery http://purl.obolibrary.org/obo/UBERON_0002456 CHEBI:84171 biolink:ChemicalSubstance 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84171 chebi_ph7_3 GO:0061978 biolink:BiologicalProcess mandibular condyle articular cartilage development The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0061978 CHEBI:84170 biolink:ChemicalSubstance 4-hydroxy-6-nonadecylpyran-2-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_84170 chebi_ph7_3 UBERON:0002458 biolink:AnatomicalEntity spinal artery Arteries that supply the spinal cord. go-plus.json spinal arteries http://purl.obolibrary.org/obo/UBERON_0002458 CHEBI:25848 biolink:ChemicalSubstance pantothenic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_25848 UBERON:0002457 biolink:AnatomicalEntity intersomitic artery The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries go-plus.json intersegmental arteries|intersegmental artery http://purl.obolibrary.org/obo/UBERON_0002457 SO:0001659 biolink:SequenceFeature promoter_element An element that can exist within the promoter region of a gene. go-plus.json promoter element http://purl.obolibrary.org/obo/SO_0001659 SO:0001654 biolink:SequenceFeature nucleotide_to_protein_binding_site A binding site that, in the nucleotide molecule, interacts selectively and non-covalently with polypeptide residues. go-plus.json nucleotide to protein binding site http://purl.obolibrary.org/obo/SO_0001654 SOFA UBERON:0002451 biolink:AnatomicalEntity endometrial gland The mucous secreting gland associated with the mucuous membrane lining the uterus. go-plus.json glandulae uterinae|endometrial gland|endometrial mucuous gland|endometrium gland|glandulae uterinae|uterine gland http://purl.obolibrary.org/obo/UBERON_0002451 CL:0002131 biolink:Cell regular ventricular cardiac myocyte Regular cardiac myocyte of a cardiac ventricle. go-plus.json ventricular myocyte|regular ventricular cardiac muscle fiber|ventricular cardiac muscle cell|regular cardiac muscle cell of ventricle http://purl.obolibrary.org/obo/CL_0002131 GO:0046363 biolink:BiologicalProcess ribitol catabolic process The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. go-plus.json ribitol catabolism|ribitol degradation|ribitol breakdown http://purl.obolibrary.org/obo/GO_0046363 GO:0046362 biolink:BiologicalProcess ribitol biosynthetic process The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. go-plus.json ribitol formation|ribitol biosynthesis|ribitol anabolism|ribitol synthesis http://purl.obolibrary.org/obo/GO_0046362 GO:0046361 biolink:BiologicalProcess 2-oxobutyrate metabolic process The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2. go-plus.json alpha-ketobutyrate metabolic process|alpha-ketobutyrate metabolism|2-oxobutyrate metabolism http://purl.obolibrary.org/obo/GO_0046361 GO:0046360 biolink:BiologicalProcess 2-oxobutyrate biosynthetic process The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2. go-plus.json 2-oxobutyrate anabolism|2-oxobutyrate synthesis|2-oxobutyrate formation|alpha-ketobutyrate biosynthesis|alpha-ketobutyrate biosynthetic process|2-oxobutyrate biosynthesis http://purl.obolibrary.org/obo/GO_0046360 GO:1900437 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1900437 GO:1900436 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms in response to starvation Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json up regulation of filamentous growth of a population of unicellular organisms in response to starvation|activation of filamentous growth of a population of unicellular organisms in response to starvation|up-regulation of filamentous growth of a population of unicellular organisms in response to starvation|upregulation of filamentous growth of a population of unicellular organisms in response to starvation http://purl.obolibrary.org/obo/GO_1900436 CHEBI:25812 biolink:ChemicalSubstance ozone go-plus.json http://purl.obolibrary.org/obo/CHEBI_25812 chebi_ph7_3 GO:1900439 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus. go-plus.json upregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|activation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus http://purl.obolibrary.org/obo/GO_1900439 GO:1900438 biolink:BiologicalProcess negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus. go-plus.json down-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|inhibition of filamentous growth of a population of unicellular organisms in response to chemical stimulus http://purl.obolibrary.org/obo/GO_1900438 CHEBI:25810 biolink:ChemicalSubstance oxopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_25810 GO:1900433 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms in response to heat Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat. go-plus.json activation of filamentous growth of a population of unicellular organisms in response to heat|up-regulation of filamentous growth of a population of unicellular organisms in response to heat|upregulation of filamentous growth of a population of unicellular organisms in response to heat|up regulation of filamentous growth of a population of unicellular organisms in response to heat http://purl.obolibrary.org/obo/GO_1900433 CL:0002108 biolink:Cell CD38-negative IgG memory B cell A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002108 GO:1900432 biolink:BiologicalProcess negative regulation of filamentous growth of a population of unicellular organisms in response to heat Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat. go-plus.json down-regulation of filamentous growth of a population of unicellular organisms in response to heat|inhibition of filamentous growth of a population of unicellular organisms in response to heat|down regulation of filamentous growth of a population of unicellular organisms in response to heat|downregulation of filamentous growth of a population of unicellular organisms in response to heat http://purl.obolibrary.org/obo/GO_1900432 CL:0002107 biolink:Cell IgD-negative CD38-positive IgG memory B cell An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002107 GO:1900435 biolink:BiologicalProcess obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json down-regulation of filamentous growth of a population of unicellular organisms in response to starvation|inhibition of filamentous growth of a population of unicellular organisms in response to starvation|down regulation of filamentous growth of a population of unicellular organisms in response to starvation|downregulation of filamentous growth of a population of unicellular organisms in response to starvation http://purl.obolibrary.org/obo/GO_1900435 GO:0046369 biolink:BiologicalProcess galactose biosynthetic process The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose. go-plus.json galactose anabolism|galactose synthesis|galactose formation|galactose biosynthesis http://purl.obolibrary.org/obo/GO_0046369 GO:1900434 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms in response to starvation Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation. go-plus.json http://purl.obolibrary.org/obo/GO_1900434 CL:0002109 biolink:Cell B220-positive CD38-positive naive B cell A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. go-plus.json CD38+B220+ naive B cell|B220+CD38+ naive B-cell|CD38+B220+ naive B lymphocyte|B220-positive CD38-positive naive B lymphocyte|B220+CD38+ naive B-lymphocyte|B220+CD38+ naive B cell|B220-positive CD38-positive naive B-cell|CD38+B220+ naive B-cell|B220+CD38+ naive B lymphocyte|CD38+B220+ naive B-lymphocyte|B220-positive CD38-positive naive B-lymphocyte http://purl.obolibrary.org/obo/CL_0002109 GO:0046368 biolink:BiologicalProcess GDP-L-fucose metabolic process The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-L-fucose metabolism http://purl.obolibrary.org/obo/GO_0046368 GO:0046367 biolink:BiologicalProcess allose catabolic process The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. go-plus.json allose degradation|allose breakdown|allose catabolism http://purl.obolibrary.org/obo/GO_0046367 GO:0046366 biolink:BiologicalProcess allose biosynthetic process The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. go-plus.json allose anabolism|allose synthesis|allose formation|allose biosynthesis http://purl.obolibrary.org/obo/GO_0046366 GO:0046365 biolink:BiologicalProcess monosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. go-plus.json monosaccharide breakdown|monosaccharide catabolism|monosaccharide degradation http://purl.obolibrary.org/obo/GO_0046365 GO:1900431 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms in response to heat Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat. go-plus.json http://purl.obolibrary.org/obo/GO_1900431 GO:1900430 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms. go-plus.json upregulation of filamentous growth of a population of unicellular organisms|up regulation of filamentous growth of a population of unicellular organisms|activation of filamentous growth of a population of unicellular organisms|up-regulation of filamentous growth of a population of unicellular organisms http://purl.obolibrary.org/obo/GO_1900430 GO:0046364 biolink:BiologicalProcess monosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. go-plus.json monosaccharide anabolism|monosaccharide synthesis|monosaccharide formation|monosaccharide biosynthesis http://purl.obolibrary.org/obo/GO_0046364 CHEBI:84189 biolink:ChemicalSubstance L-threonine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84189 CL:0002102 biolink:Cell CD38-negative naive B cell A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. go-plus.json CD38- naive B-cell|CD38- naive B-lymphocyte|CD38-negative naive B lymphocyte|CD38- naive B cell|CD38- naive B lymphocyte|CD38-negative naive B-cell|CD38-negative naive B-lymphocyte http://purl.obolibrary.org/obo/CL_0002102 CL:0002101 biolink:Cell CD38-positive naive B cell A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. go-plus.json CD38-positive naive B-lymphocyte|CD38+ naive B-cell|CD38+ naive B-lymphocyte|CD38-positive naive B lymphocyte|CD38+ naive B cell|CD38+ naive B lymphocyte|CD38-positive naive B-cell http://purl.obolibrary.org/obo/CL_0002101 CHEBI:84187 biolink:ChemicalSubstance 2-epi-5-epi-valiolone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84187 chebi_ph7_3 CL:0002104 biolink:Cell IgG-negative double negative memory B cell An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative. go-plus.json IgG- double negative memory B cell|IgG-negative double negative memory B-lymphocyte|IgG- dn memory B cell|IgG- double negative memory B lymphocyte|IgG- dn memory B lymphocyte|IgG-negative dn memory B-cell|IgG-negative dn memory B-lymphocyte|IgG-negative double negative memory B lymphocyte|IgG- double negative memory B-cell|IgG- dn memory B-cell|IgG- double negative memory B-lymphocyte|IgG-negative dn memory B cell|IgG- dn memory B-lymphocyte|IgG-negative dn memory B lymphocyte|IgG-negative double negative memory B-cell http://purl.obolibrary.org/obo/CL_0002104 CHEBI:84186 biolink:ChemicalSubstance L-proline derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84186 CL:0002103 biolink:Cell IgG-positive double negative memory B cell An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative. go-plus.json IgG+ dn memory B cell|IgG+ double negative memory B cell|IgG+ dn memory B lymphocyte|IgG+ double negative memory B lymphocyte|IgG-positive double negative memory B lymphocyte|IgG-positive dn memory B-cell|IgG-positive dn memory B-lymphocyte|IgG+ dn memory B-cell|IgG+ double negative memory B-cell|IgG+ dn memory B-lymphocyte|IgG+ double negative memory B-lymphocyte|IgG-positive double negative memory B-cell|IgG-positive dn memory B cell|IgG-positive double negative memory B-lymphocyte|IgG-positive dn memory B lymphocyte http://purl.obolibrary.org/obo/CL_0002103 CHEBI:84185 biolink:ChemicalSubstance D-proline derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84185 GO:0071329 biolink:BiologicalProcess cellular response to sucrose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071329 CL:0002106 biolink:Cell IgD-positive CD38-positive IgG memory B cell An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002106 CHEBI:84184 biolink:ChemicalSubstance 3-methylundecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84184 chebi_ph7_3 GO:0071328 biolink:BiologicalProcess cellular response to maltose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071328 CL:0002105 biolink:Cell CD38-positive IgG memory B cell A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. go-plus.json CD38-positive IgG memory B lymphocyte|CD38+ IgG memory B-cell|CD38+ IgG memory B-lymphocyte|CD38-positive IgG memory B-cell|CD38-positive IgG memory B-lymphocyte|CD38+ IgG memory B cell|CD38+ IgG memory B lymphocyte http://purl.obolibrary.org/obo/CL_0002105 CHEBI:84183 biolink:ChemicalSubstance 3-methylundecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84183 chebi_ph7_3 CHEBI:84182 biolink:ChemicalSubstance 2-methylhexadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84182 chebi_ph7_3 GO:0071327 biolink:BiologicalProcess cellular response to trehalose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071327 GO:0071326 biolink:BiologicalProcess cellular response to monosaccharide stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071326 CHEBI:84181 biolink:ChemicalSubstance 12-methyloctadecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84181 chebi_ph7_3 GO:0071325 biolink:BiologicalProcess cellular response to mannitol stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071325 CHEBI:84180 biolink:ChemicalSubstance 10-HPO(6,8,12)TrE go-plus.json http://purl.obolibrary.org/obo/CHEBI_84180 GO:0071324 biolink:BiologicalProcess cellular response to disaccharide stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071324 GO:0071323 biolink:BiologicalProcess cellular response to chitin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071323 GO:0071322 biolink:BiologicalProcess cellular response to carbohydrate stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071322 GO:0071321 biolink:BiologicalProcess cellular response to cGMP Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus. go-plus.json cellular response to guanosine 3',5'-cyclophosphate|cellular response to 3',5'-cGMP|cellular response to cyclic GMP|cellular response to 3',5' cGMP http://purl.obolibrary.org/obo/GO_0071321 GO:0071320 biolink:BiologicalProcess cellular response to cAMP Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus. go-plus.json cellular response to 3',5'-cAMP|cellular response to adenosine 3',5'-cyclophosphate|cellular response to cyclic AMP|cellular response to 3',5' cAMP http://purl.obolibrary.org/obo/GO_0071320 SO:0001683 biolink:SequenceFeature sequence_motif A sequence motif is a nucleotide or amino-acid sequence pattern that may have biological significance. http://en.wikipedia.org/wiki/Sequence_motif go-plus.json sequence motif http://purl.obolibrary.org/obo/SO_0001683 SOFA GO:0046374 biolink:BiologicalProcess teichoic acid metabolic process The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues. go-plus.json teichoic acid metabolism http://purl.obolibrary.org/obo/GO_0046374 GO:0046373 biolink:BiologicalProcess L-arabinose metabolic process The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc. go-plus.json L-arabinose metabolism http://purl.obolibrary.org/obo/GO_0046373 GO:0046372 biolink:BiologicalProcess D-arabinose metabolic process The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides. go-plus.json D-arabinose metabolism http://purl.obolibrary.org/obo/GO_0046372 GO:0046371 biolink:BiologicalProcess dTDP-mannose metabolic process The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate. go-plus.json dTDP-mannose metabolism http://purl.obolibrary.org/obo/GO_0046371 GO:0046370 biolink:BiologicalProcess fructose biosynthetic process The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose. go-plus.json fructose biosynthesis|fructose anabolism|fructose synthesis|fructose formation http://purl.obolibrary.org/obo/GO_0046370 GO:1900448 biolink:BiologicalProcess obsolete regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1900448 GO:1900447 biolink:BiologicalProcess regulation of cell morphogenesis involved in phenotypic switching Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. go-plus.json regulation of cell shape and cell size of phenotypic switching|regulation of cell shape and cell size of phenotypic dimorphism|positive regulation of cell shape and cell size of phenotypic dimorphism|regulation of cell morphogenesis of phenotypic dimorphism|negative regulation of cell shape and cell size of phenotypic dimorphism|regulation of cell morphogenesis of phenotypic switching|negative regulation of cell shape and cell size of phenotypic switching|positive regulation of cell shape and cell size of phenotypic switching http://purl.obolibrary.org/obo/GO_1900447 CHEBI:25822 biolink:ChemicalSubstance p-cumate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25822 chebi_ph7_3 GO:1900449 biolink:BiologicalProcess regulation of glutamate receptor signaling pathway Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. go-plus.json regulation of glutamate signaling pathway|regulation of glutamate signalling pathway http://purl.obolibrary.org/obo/GO_1900449 GO:1900444 biolink:BiologicalProcess negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus. go-plus.json down-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|inhibition of filamentous growth of a population of unicellular organisms in response to biotic stimulus http://purl.obolibrary.org/obo/GO_1900444 CL:0002119 biolink:Cell CD38-positive IgG-negative class switched memory B cell A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002119 PR:000021066 biolink:Protein pancreatic prohormone proteolytic cleavage product A pancreatic prohormone that has been processed by proteolytic cleavage. go-plus.json PPY/ClvPrd http://purl.obolibrary.org/obo/PR_000021066 GO:1900443 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_1900443 CL:0002118 biolink:Cell CD38-negative IgG-negative class switched memory B cell A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002118 GO:1900446 biolink:BiologicalProcess obsolete negative regulation of tRNA transcription from RNA polymerase III promoter OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tRNA transcription from RNA polymerase III promoter. go-plus.json down-regulation of tRNA transcription from Pol III promoter|negative regulation of tRNA transcription from Pol III promoter|down-regulation of tRNA transcription from RNA polymerase III promoter|inhibition of tRNA transcription from RNA polymerase III promoter|downregulation of tRNA transcription from Pol III promoter|down regulation of tRNA transcription from Pol III promoter|down regulation of tRNA transcription from RNA polymerase III promoter|inhibition of tRNA transcription from Pol III promoter|downregulation of tRNA transcription from RNA polymerase III promoter http://purl.obolibrary.org/obo/GO_1900446 GO:1900445 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus. go-plus.json upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|activation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|up regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus http://purl.obolibrary.org/obo/GO_1900445 GO:0046379 biolink:BiologicalProcess extracellular polysaccharide metabolic process The chemical reactions and pathways involving polysaccharides used in extracellular structures. go-plus.json extracellular polysaccharide metabolism http://purl.obolibrary.org/obo/GO_0046379 GO:0046378 biolink:BiologicalProcess enterobacterial common antigen metabolic process The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria. go-plus.json enterobacterial common antigen metabolism http://purl.obolibrary.org/obo/GO_0046378 GO:1900440 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms in response to neutral pH Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH. go-plus.json http://purl.obolibrary.org/obo/GO_1900440 GO:0046377 biolink:BiologicalProcess colanic acid metabolic process The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues. go-plus.json colanic acid metabolism http://purl.obolibrary.org/obo/GO_0046377 GO:1900442 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH. go-plus.json upregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|up regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|activation of filamentous growth of a population of unicellular organisms in response to neutral pH|up-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH http://purl.obolibrary.org/obo/GO_1900442 GO:0046376 biolink:BiologicalProcess GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolism http://purl.obolibrary.org/obo/GO_0046376 GO:0061990 biolink:MolecularActivity beta-ketodecanoyl-[acyl-carrier-protein] synthase activity Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2. RHEA:42264|MetaCyc:RXN-13613 go-plus.json http://purl.obolibrary.org/obo/GO_0061990 GO:0046375 biolink:BiologicalProcess K antigen metabolic process The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens. go-plus.json K antigen metabolism http://purl.obolibrary.org/obo/GO_0046375 GO:1900441 biolink:BiologicalProcess negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH. go-plus.json down regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|downregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|down-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|inhibition of filamentous growth of a population of unicellular organisms in response to neutral pH http://purl.obolibrary.org/obo/GO_1900441 GO:0061993 biolink:CellularComponent calcium:proton antiporter complex A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in). go-plus.json CAX1-CAX3 complex|CAX3 homodimer|CAX1 homodimer http://purl.obolibrary.org/obo/GO_0061993 CL:0002111 biolink:Cell CD38-negative unswitched memory B cell An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. go-plus.json CD38- unswitched memory B-cell|CD38- unswitched memory B-lymphocyte|CD38-negative unswitched memory B lymphocyte|CD38- unswitched memory B cell|CD38- unswitched memory B lymphocyte|CD38-negative unswitched memory B-cell|CD38-negative unswitched memory B-lymphocyte http://purl.obolibrary.org/obo/CL_0002111 GO:0061992 biolink:BiologicalProcess obsolete ATP-dependent chaperone mediated protein folding OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and dependent on ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0061992 CL:0002110 biolink:Cell B220-low CD38-positive naive B cell A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. go-plus.json http://purl.obolibrary.org/obo/CL_0002110 GO:0061995 biolink:MolecularActivity ATP-dependent protein-DNA complex displacement activity An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis. go-plus.json ATP-dependent protein-nucleic acid complex displacement activity http://purl.obolibrary.org/obo/GO_0061995 CL:0002113 biolink:Cell B220-low CD38-negative unswitched memory B cell A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002113 CL:0002112 biolink:Cell B220-positive CD38-negative unswitched memory B cell A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002112 GO:0061994 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0061994 CHEBI:84198 biolink:ChemicalSubstance 3-hydroxytetradecanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84198 chebi_ph7_3 CL:0002115 biolink:Cell B220-positive CD38-positive unswitched memory B cell A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002115 CHEBI:84197 biolink:ChemicalSubstance 3-hydroxytetradecanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84197 chebi_ph7_3 GO:0071319 biolink:BiologicalProcess cellular response to benzoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071319 CL:0002114 biolink:Cell CD38-positive unswitched memory B cell A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. go-plus.json CD38-positive unswitched memory B-lymphocyte|CD38+ unswitched memory B-cell|CD38+ unswitched memory B-lymphocyte|CD38-positive unswitched memory B lymphocyte|CD38+ unswitched memory B cell|CD38+ unswitched memory B lymphocyte|CD38-positive unswitched memory B-cell http://purl.obolibrary.org/obo/CL_0002114 CHEBI:84196 biolink:ChemicalSubstance 3-hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84196 chebi_ph7_3 GO:0061999 biolink:BiologicalProcess regulation of cardiac endothelial to mesenchymal transition Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition. go-plus.json http://purl.obolibrary.org/obo/GO_0061999 CL:0002117 biolink:Cell IgG-negative class switched memory B cell A class switched memory B cell that lacks IgG on the cell surface. go-plus.json IgG- class switched memory B cell|IgG- class switched memory B lymphocyte|IgG-negative class switched memory B-cell|IgG-negative class switched memory B-lymphocyte|IgG- class switched memory B-cell|IgG- class switched memory B-lymphocyte|IgG-negative class switched memory B lymphocyte http://purl.obolibrary.org/obo/CL_0002117 GO:0071318 biolink:BiologicalProcess cellular response to ATP Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. go-plus.json cellular response to adenosine 5'-triphosphate|cellular response to adenosine triphosphate http://purl.obolibrary.org/obo/GO_0071318 CHEBI:84195 biolink:ChemicalSubstance isomyristoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84195 chebi_ph7_3 GO:0071317 biolink:BiologicalProcess cellular response to isoquinoline alkaloid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids. go-plus.json http://purl.obolibrary.org/obo/GO_0071317 CL:0002116 biolink:Cell B220-low CD38-positive unswitched memory B cell A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002116 CHEBI:84194 biolink:ChemicalSubstance hydroxytryptophan go-plus.json http://purl.obolibrary.org/obo/CHEBI_84194 CHEBI:84193 biolink:ChemicalSubstance isomyristate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84193 chebi_ph7_3 GO:0071316 biolink:BiologicalProcess cellular response to nicotine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071316 GO:0071315 biolink:BiologicalProcess cellular response to morphine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure. go-plus.json http://purl.obolibrary.org/obo/GO_0071315 GO:0071314 biolink:BiologicalProcess cellular response to cocaine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. go-plus.json http://purl.obolibrary.org/obo/GO_0071314 CHEBI:25826 biolink:ChemicalSubstance p-menthane go-plus.json http://purl.obolibrary.org/obo/CHEBI_25826 chebi_ph7_3 CHEBI:84191 biolink:ChemicalSubstance D-glucaro-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84191 GO:0071313 biolink:BiologicalProcess cellular response to caffeine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them. go-plus.json http://purl.obolibrary.org/obo/GO_0071313 CHEBI:84190 biolink:ChemicalSubstance D-galactaro-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84190 GO:0071312 biolink:BiologicalProcess cellular response to alkaloid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. go-plus.json http://purl.obolibrary.org/obo/GO_0071312 GO:0071311 biolink:BiologicalProcess cellular response to acetate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071311 GO:0071310 biolink:BiologicalProcess cellular response to organic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071310 GO:0071341 biolink:CellularComponent medial cortical node A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis. go-plus.json midsome|mid1p medial cortical dot http://purl.obolibrary.org/obo/GO_0071341 GO:0046385 biolink:BiologicalProcess deoxyribose phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. go-plus.json deoxyribose phosphate anabolism|deoxyribose phosphate synthesis|deoxyribose phosphate formation|deoxyribose phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0046385 GO:0046384 biolink:BiologicalProcess 2-deoxyribose 1-phosphate metabolic process The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose. go-plus.json 2-deoxyribose 1-phosphate metabolism|deoxyribose 1-phosphate metabolic process|deoxyribose 1-phosphate metabolism http://purl.obolibrary.org/obo/GO_0046384 GO:0071340 biolink:BiologicalProcess skeletal muscle acetylcholine-gated channel clustering The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals. go-plus.json skeletal muscle nicotinic acetylcholine receptor clustering|skeletal muscle AChR clustering http://purl.obolibrary.org/obo/GO_0071340 GO:0046383 biolink:BiologicalProcess dTDP-rhamnose metabolic process The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate. go-plus.json dTDP-rhamnose metabolism http://purl.obolibrary.org/obo/GO_0046383 GO:0046382 biolink:BiologicalProcess GDP-D-rhamnose metabolic process The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate. go-plus.json GDP-D-rhamnose metabolism http://purl.obolibrary.org/obo/GO_0046382 NCBITaxon:32064 biolink:OrganismalEntity Chloroflexales go-plus.json Chloroflexaceae group|Chloroflexus group http://purl.obolibrary.org/obo/NCBITaxon_32064 GO:1900459 biolink:BiologicalProcess positive regulation of brassinosteroid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway. go-plus.json upregulation of brassinosteroid mediated signalling|upregulation of brassinosteroid mediated signaling pathway|up regulation of brassinosteroid mediated signalling|positive regulation of brassinosteroid mediated signalling|up-regulation of brassinosteroid mediated signaling pathway|activation of brassinosteroid mediated signaling pathway|activation of brassinosteroid mediated signalling|up-regulation of brassinosteroid mediated signalling|up regulation of brassinosteroid mediated signaling pathway http://purl.obolibrary.org/obo/GO_1900459 GO:0046381 biolink:BiologicalProcess CMP-N-acetylneuraminate metabolic process The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate. go-plus.json CMP-N-acetylneuraminate metabolism http://purl.obolibrary.org/obo/GO_0046381 GO:0046380 biolink:BiologicalProcess N-acetylneuraminate biosynthetic process The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. go-plus.json N-acetylneuraminate synthesis|N-acetylneuraminate formation|N-acetylneuraminate biosynthesis|N-acetylneuraminate anabolism http://purl.obolibrary.org/obo/GO_0046380 GO:1900458 biolink:BiologicalProcess negative regulation of brassinosteroid mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway. go-plus.json down regulation of brassinosteroid mediated signaling pathway|down regulation of brassinosteroid mediated signalling|inhibition of brassinosteroid mediated signaling pathway|downregulation of brassinosteroid mediated signalling|down-regulation of brassinosteroid mediated signalling|negative regulation of brassinosteroid mediated signalling|down-regulation of brassinosteroid mediated signaling pathway|inhibition of brassinosteroid mediated signalling|downregulation of brassinosteroid mediated signaling pathway http://purl.obolibrary.org/obo/GO_1900458 NCBITaxon:32061 biolink:OrganismalEntity Chloroflexia go-plus.json Chloroflexi|Chloroflexus/Deinococcaceae group|Chloroflexus/Deinococcus group|Chloroflexaceae/Deinococcaceae group http://purl.obolibrary.org/obo/NCBITaxon_32061 GO:1900455 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900455 GO:1900454 biolink:BiologicalProcess positive regulation of long-term synaptic depression Any process that activates or increases the frequency, rate or extent of long term synaptic depression. go-plus.json up regulation of LTD|positive regulation of LTD|up-regulation of long term synaptic depression|upregulation of long term depression|activation of LTD|positive regulation of long term synaptic depression|up-regulation of LTD|upregulation of long term synaptic depression|up-regulation of long term depression|activation of long term depression|upregulation of LTD|up regulation of long term synaptic depression|positive regulation of long term depression|activation of long term synaptic depression|up regulation of long term depression http://purl.obolibrary.org/obo/GO_1900454 GO:1900457 biolink:BiologicalProcess regulation of brassinosteroid mediated signaling pathway Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway. go-plus.json regulation of brassinosteroid mediated signalling http://purl.obolibrary.org/obo/GO_1900457 GO:1900456 biolink:BiologicalProcess obsolete regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter|regulation of colony morphology by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900456 GO:1900451 biolink:BiologicalProcess positive regulation of glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. go-plus.json up-regulation of glutamate signaling pathway|positive regulation of glutamate signalling pathway|up regulation of glutamate signalling pathway|upregulation of glutamate signaling pathway|up regulation of glutamate receptor signaling pathway|upregulation of glutamate signalling pathway|up regulation of glutamate signaling pathway|positive regulation of glutamate signaling pathway|upregulation of glutamate receptor signaling pathway|up-regulation of glutamate signalling pathway|activation of glutamate signaling pathway|activation of glutamate signalling pathway|up-regulation of glutamate receptor signaling pathway|activation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900451 GO:0046389 biolink:BiologicalProcess deoxyribose 5-phosphate metabolic process The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose. go-plus.json deoxyribose 5-phosphate metabolism http://purl.obolibrary.org/obo/GO_0046389 GO:1900450 biolink:BiologicalProcess negative regulation of glutamate receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. go-plus.json inhibition of glutamate signaling pathway|down-regulation of glutamate receptor signaling pathway|downregulation of glutamate signalling pathway|down regulation of glutamate signalling pathway|down regulation of glutamate signaling pathway|downregulation of glutamate receptor signaling pathway|downregulation of glutamate signaling pathway|inhibition of glutamate signalling pathway|down regulation of glutamate receptor signaling pathway|inhibition of glutamate receptor signaling pathway|down-regulation of glutamate signaling pathway|negative regulation of glutamate signaling pathway|down-regulation of glutamate signalling pathway|negative regulation of glutamate signalling pathway http://purl.obolibrary.org/obo/GO_1900450 GO:0046388 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046388 GO:1900453 biolink:BiologicalProcess negative regulation of long-term synaptic depression Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression. go-plus.json down-regulation of long term synaptic depression|downregulation of long term depression|down regulation of long term depression|inhibition of long term synaptic depression|negative regulation of LTD|down-regulation of LTD|inhibition of long term depression|down regulation of long term synaptic depression|inhibition of LTD|negative regulation of long term synaptic depression|downregulation of long term synaptic depression|down-regulation of long term depression|negative regulation of long term depression|down regulation of LTD|downregulation of LTD http://purl.obolibrary.org/obo/GO_1900453 GO:0046387 biolink:BiologicalProcess deoxyribose 1,5-bisphosphate metabolic process The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose. go-plus.json deoxyribose 1,5-bisphosphate metabolism http://purl.obolibrary.org/obo/GO_0046387 GO:1900452 biolink:BiologicalProcess regulation of long-term synaptic depression Any process that modulates the frequency, rate or extent of long term synaptic depression. go-plus.json regulation of long term depression|regulation of long term synaptic depression|regulation of LTD http://purl.obolibrary.org/obo/GO_1900452 GO:0046386 biolink:BiologicalProcess deoxyribose phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. go-plus.json deoxyribose phosphate catabolism|deoxyribose phosphate degradation|deoxyribose phosphate breakdown http://purl.obolibrary.org/obo/GO_0046386 GO:1900460 biolink:BiologicalProcess obsolete negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of colony morphology by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900460 GO:0071349 biolink:BiologicalProcess cellular response to interleukin-12 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus. go-plus.json cellular response to IL-12 http://purl.obolibrary.org/obo/GO_0071349 GO:0071348 biolink:BiologicalProcess cellular response to interleukin-11 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus. go-plus.json cellular response to IL-11 http://purl.obolibrary.org/obo/GO_0071348 GO:0071347 biolink:BiologicalProcess cellular response to interleukin-1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. go-plus.json cellular response to IL-1 http://purl.obolibrary.org/obo/GO_0071347 GO:0071346 biolink:BiologicalProcess cellular response to interferon-gamma Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. go-plus.json cellular response to type II IFN|cellular response to type II interferon|cellular response to immune interferon|cellular response to gamma-interferon http://purl.obolibrary.org/obo/GO_0071346 GO:0071345 biolink:BiologicalProcess cellular response to cytokine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071345 GO:0071344 biolink:BiologicalProcess diphosphate metabolic process The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid. go-plus.json pyrophosphate metabolism http://purl.obolibrary.org/obo/GO_0071344 NCBITaxon:32066 biolink:OrganismalEntity Fusobacteria go-plus.json Fusobacteraeota|fusobacteria|Fusobacteriota http://purl.obolibrary.org/obo/NCBITaxon_32066 NCBITaxon:32069 biolink:OrganismalEntity Aquificales go-plus.json aquificales|Oxygen reducing bacteria|Oxygen-reducing bacteria|Obligately chemolithotrophic hydrogen bacteria|Hydrogenic oxygen reducing bacteria http://purl.obolibrary.org/obo/NCBITaxon_32069 GO:0071343 biolink:BiologicalProcess obsolete negative regulation of establishment of actomyosin contractile ring localization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location. go-plus.json negative regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|negative regulation of establishment of contractile ring localization involved in cell cycle cytokinesis|negative regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle|negative regulation of establishment of actomyosin contractile ring localization http://purl.obolibrary.org/obo/GO_0071343 GO:0071342 biolink:BiologicalProcess regulation of establishment of actomyosin contractile ring localization Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle. go-plus.json regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|regulation of establishment of contractile ring localization involved in cell cycle cytokinesis|regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle http://purl.obolibrary.org/obo/GO_0071342 GO:0046396 biolink:BiologicalProcess D-galacturonate metabolic process The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls. go-plus.json D-galacturonate metabolism http://purl.obolibrary.org/obo/GO_0046396 GO:0071330 biolink:BiologicalProcess cellular response to trehalose-6-phosphate stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071330 GO:0046395 biolink:BiologicalProcess carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. go-plus.json carboxylic acid degradation|carboxylic acid breakdown|carboxylic acid catabolism http://purl.obolibrary.org/obo/GO_0046395 GO:0046394 biolink:BiologicalProcess carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. go-plus.json carboxylic acid synthesis|carboxylic acid formation|carboxylic acid biosynthesis|carboxylic acid anabolism http://purl.obolibrary.org/obo/GO_0046394 GO:0046393 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046393 GO:0046392 biolink:BiologicalProcess galactarate catabolic process The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid. MetaCyc:GALACTARDEG-PWY go-plus.json galactarate catabolism|galactarate degradation|galactarate breakdown|D-galactarate degradation|D-galactarate breakdown|D-galactarate catabolism|D-galactarate catabolic process http://purl.obolibrary.org/obo/GO_0046392 GO:1900469 biolink:BiologicalProcess negative regulation of phosphatidylserine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process. go-plus.json inhibition of phosphatidylserine biosynthetic process|inhibition of phosphatidylserine formation|inhibition of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine anabolism|down-regulation of phosphatidylserine anabolism|negative regulation of phosphatidylserine synthesis|down-regulation of phosphatidylserine synthesis|down regulation of phosphatidylserine biosynthetic process|down regulation of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine formation|down-regulation of phosphatidylserine formation|downregulation of phosphatidylserine anabolism|downregulation of phosphatidylserine biosynthetic process|downregulation of phosphatidylserine biosynthesis|downregulation of phosphatidylserine synthesis|down regulation of phosphatidylserine anabolism|downregulation of phosphatidylserine formation|down regulation of phosphatidylserine synthesis|down-regulation of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine biosynthesis|down-regulation of phosphatidylserine biosynthetic process|inhibition of phosphatidylserine anabolism|down regulation of phosphatidylserine formation|inhibition of phosphatidylserine synthesis http://purl.obolibrary.org/obo/GO_1900469 CHEBI:25801 biolink:ChemicalSubstance oxoproline go-plus.json http://purl.obolibrary.org/obo/CHEBI_25801 GO:0046391 biolink:BiologicalProcess 5-phosphoribose 1-diphosphate metabolic process The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate. MetaCyc:PRPP-PWY go-plus.json PRPP metabolic process|5-phosphoribose 1-diphosphate metabolism http://purl.obolibrary.org/obo/GO_0046391 GO:0046390 biolink:BiologicalProcess ribose phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar. go-plus.json ribose phosphate anabolism|ribose phosphate synthesis|ribose phosphate formation|ribose phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0046390 GO:1900466 biolink:BiologicalProcess obsolete positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json upregulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|activation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900466 GO:1900465 biolink:BiologicalProcess obsolete negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cellular arginine catabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of arginine degradation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine breakdown by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine catabolism by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900465 GO:1900468 biolink:BiologicalProcess regulation of phosphatidylserine biosynthetic process Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process. go-plus.json regulation of phosphatidylserine biosynthesis|regulation of phosphatidylserine anabolism|regulation of phosphatidylserine synthesis|regulation of phosphatidylserine formation http://purl.obolibrary.org/obo/GO_1900468 GO:1900467 biolink:BiologicalProcess obsolete regulation of cellular potassium ion homeostasis OBSOLETE. Any process that modulates the frequency, rate or extent of cellular potassium ion homeostasis. go-plus.json regulation of cellular potassium ion homeostasis http://purl.obolibrary.org/obo/GO_1900467 GO:1900462 biolink:BiologicalProcess obsolete negative regulation of pseudohyphal growth by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1900462 GO:1900461 biolink:BiologicalProcess positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json http://purl.obolibrary.org/obo/GO_1900461 GO:0046399 biolink:BiologicalProcess glucuronate biosynthetic process The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid. go-plus.json glucuronate biosynthesis|glucuronate anabolism|glucuronate synthesis|glucuronate formation http://purl.obolibrary.org/obo/GO_0046399 GO:0046398 biolink:BiologicalProcess UDP-glucuronate metabolic process The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. go-plus.json UDP-glucuronate metabolism http://purl.obolibrary.org/obo/GO_0046398 GO:1900464 biolink:BiologicalProcess negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of cellular hyperosmotic salinity response by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of cellular response to hyperosmotic salt stress by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900464 GO:0046397 biolink:BiologicalProcess galacturonate catabolic process The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid. go-plus.json galacturonate degradation|galacturonate catabolism|galacturonate breakdown http://purl.obolibrary.org/obo/GO_0046397 GO:1900463 biolink:BiologicalProcess negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of cellular response to alkalinity by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of cellular response to basic pH by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular response to alkalinity by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900463 UBERON:0002492 biolink:AnatomicalEntity sagittal suture the dense, fibrous connective tissue joint between the tetrapod parietal bones go-plus.json sagittal suture of skull|sutura sagittalis http://purl.obolibrary.org/obo/UBERON_0002492 UBERON:0002491 biolink:AnatomicalEntity lambdoid suture the dense, fibrous connective tissue joint between the parietal bones and the occipital bone go-plus.json lambdoidal suture|sutura lambdoidea|lambdoid suture of skull http://purl.obolibrary.org/obo/UBERON_0002491 GO:1900471 biolink:BiologicalProcess obsolete negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of inositol biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of inositol anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900471 GO:1900470 biolink:BiologicalProcess positive regulation of phosphatidylserine biosynthetic process Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process. go-plus.json upregulation of phosphatidylserine anabolism|activation of phosphatidylserine biosynthesis|upregulation of phosphatidylserine synthesis|upregulation of phosphatidylserine formation|up-regulation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine biosynthetic process|up-regulation of phosphatidylserine anabolism|up-regulation of phosphatidylserine synthesis|activation of phosphatidylserine anabolism|up-regulation of phosphatidylserine formation|upregulation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine biosynthesis|activation of phosphatidylserine synthesis|positive regulation of phosphatidylserine anabolism|up regulation of phosphatidylserine anabolism|activation of phosphatidylserine formation|positive regulation of phosphatidylserine synthesis|up regulation of phosphatidylserine synthesis|positive regulation of phosphatidylserine formation|up regulation of phosphatidylserine biosynthesis|up regulation of phosphatidylserine biosynthetic process|up regulation of phosphatidylserine formation|positive regulation of phosphatidylserine biosynthesis|activation of phosphatidylserine biosynthetic process http://purl.obolibrary.org/obo/GO_1900470 UBERON:0002490 biolink:AnatomicalEntity frontal suture A suture that connects the two frontal bones of the skull. go-plus.json metopic suture|sutura metopica|median frontal suture|frontal suture of skull|sutura frontalis|sutura frontalis http://purl.obolibrary.org/obo/UBERON_0002490 GO:0071339 biolink:CellularComponent MLL1 complex A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5. go-plus.json http://purl.obolibrary.org/obo/GO_0071339 GO:0071338 biolink:BiologicalProcess positive regulation of hair follicle cell proliferation Any process that activates or increases the rate or extent of hair follicle cell proliferation. go-plus.json upregulation of hair follicle cell proliferation|stimulation of hair follicle cell proliferation|up-regulation of hair follicle cell proliferation|activation of hair follicle cell proliferation|up regulation of hair follicle cell proliferation http://purl.obolibrary.org/obo/GO_0071338 CHEBI:25806 biolink:ChemicalSubstance oxygen molecular entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_25806 GO:0071337 biolink:BiologicalProcess negative regulation of hair follicle cell proliferation Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation. go-plus.json inhibition of hair follicle cell proliferation|down-regulation of hair follicle cell proliferation|downregulation of hair follicle cell proliferation|down regulation of hair follicle cell proliferation http://purl.obolibrary.org/obo/GO_0071337 CHEBI:25805 biolink:ChemicalSubstance oxygen atom go-plus.json http://purl.obolibrary.org/obo/CHEBI_25805 chebi_ph7_3 GO:0071336 biolink:BiologicalProcess regulation of hair follicle cell proliferation Any process that modulates the frequency, rate or extent of hair follicle cell proliferation. go-plus.json http://purl.obolibrary.org/obo/GO_0071336 GO:0071335 biolink:BiologicalProcess hair follicle cell proliferation The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population. go-plus.json http://purl.obolibrary.org/obo/GO_0071335 GO:0071334 biolink:BiologicalProcess cellular response to rhamnose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus. go-plus.json cellular response to L-rhamnose stimulus http://purl.obolibrary.org/obo/GO_0071334 GO:0071333 biolink:BiologicalProcess cellular response to glucose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071333 UBERON:0002495 biolink:AnatomicalEntity long bone Long bone is a limb bone that is subcylindrical and has a shaft with periosteum separating the ends of the bones. Long bones are present only in the limbs[VSAO:wd]. go-plus.json os longum http://purl.obolibrary.org/obo/UBERON_0002495 UBERON:0002498 biolink:AnatomicalEntity deltopectoral crest a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches go-plus.json crista ventralis humeri|pectoral process|deltoid tuberosity|crista ventralis|deltoid crest|deltoid eminence|tuberositas deltoidea humeri|tuberositas deltoidea|deltoid process|tuberositas deltoidea (corpus humeri)|deltoid impression|deltoid tuberosity of humerus http://purl.obolibrary.org/obo/UBERON_0002498 GO:0071332 biolink:BiologicalProcess cellular response to fructose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071332 CHEBI:25807 biolink:ChemicalSubstance organooxygen heterocyclic antibiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_25807 UBERON:0002497 biolink:AnatomicalEntity acromion Region of the scapula where the latter meets with the clavicle: attachment point of the clavicle to the scapula in some taxa. go-plus.json acromion of the scapula|scapular acromion|acromion process|acromion of scapula http://purl.obolibrary.org/obo/UBERON_0002497 GO:0071331 biolink:BiologicalProcess cellular response to hexose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071331 UBERON:0002519 biolink:AnatomicalEntity otolithic part of statoconial membrane The layer of the statoconial membrane that is composed of otoliths go-plus.json membrana statoconiorum|otolith layer of statoconial membrane|otolithic membrane http://purl.obolibrary.org/obo/UBERON_0002519 CHEBI:50776 biolink:ChemicalSubstance 3-decaprenyl-4-hydroxy-5-methoxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50776 UBERON:0002518 biolink:AnatomicalEntity otolith organ the crystalline particles composed of calcium carbonate and a protein which adhere to the gelatinous membrane of the maculae of the utricle and saccule (otolithic membrane) go-plus.json otolith organs|saccule and utricle|utricle and saccule http://purl.obolibrary.org/obo/UBERON_0002518 CHEBI:50775 biolink:ChemicalSubstance 3-decaprenyl-4,5-dihydroxybenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50775 CHEBI:50774 biolink:ChemicalSubstance 2-decaprenyl-6-methoxyphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50774 chebi_ph7_3 CHEBI:74744 biolink:ChemicalSubstance N(6),N(6)-dimethyladenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74744 UBERON:0002514 biolink:AnatomicalEntity intramembranous bone Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. go-plus.json membrane bone|intramembranous bones http://purl.obolibrary.org/obo/UBERON_0002514 CHEBI:50779 biolink:ChemicalSubstance appetite enhancer go-plus.json http://purl.obolibrary.org/obo/CHEBI_50779 UBERON:0002517 biolink:AnatomicalEntity basicranium The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof. go-plus.json basis cranii|cranial base|base of cranium|base of skull http://purl.obolibrary.org/obo/UBERON_0002517 CHEBI:74748 biolink:ChemicalSubstance 2'-O-methylcytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74748 CHEBI:60102 biolink:ChemicalSubstance sulfurated eukaryotic molybdenum cofactor(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60102 CHEBI:35135 biolink:ChemicalSubstance iron-sulfur protein go-plus.json http://purl.obolibrary.org/obo/CHEBI_35135 CHEBI:35134 biolink:ChemicalSubstance metalloprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_35134 CHEBI:60101 biolink:ChemicalSubstance UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60101 chebi_ph7_3 CHEBI:60104 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_60104 CHEBI:35137 biolink:ChemicalSubstance hemoprotein go-plus.json http://purl.obolibrary.org/obo/CHEBI_35137 CHEBI:35136 biolink:ChemicalSubstance iron protein go-plus.json http://purl.obolibrary.org/obo/CHEBI_35136 CHEBI:35139 biolink:ChemicalSubstance uronic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35139 CHEBI:60106 biolink:ChemicalSubstance streptidine 6-phosphate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60106 chebi_ph7_3 CHEBI:35138 biolink:ChemicalSubstance aldotetrose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35138 CHEBI:60105 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl(1-) group go-plus.json http://purl.obolibrary.org/obo/CHEBI_60105 chebi_ph7_3 CHEBI:60108 biolink:ChemicalSubstance 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60108 chebi_ph7_3 CHEBI:60107 biolink:ChemicalSubstance N(5)-[(hydroxyamino)(imino)methyl]-L-ornithinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60107 chebi_ph7_3 UBERON:0002522 biolink:AnatomicalEntity tunica media The middle layer of an artery or vein. [WP,unvetted]. go-plus.json tunica media vasorum http://purl.obolibrary.org/obo/UBERON_0002522 UBERON:0002521 biolink:AnatomicalEntity elastic tissue Connective tissue composed of elastic fibers. go-plus.json elastic connective tissue|elastic fiber|textus connectivus elasticus http://purl.obolibrary.org/obo/UBERON_0002521 CHEBI:60109 biolink:ChemicalSubstance 3-[(5R,6S)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60109 chebi_ph7_3 CHEBI:59108 biolink:ChemicalSubstance N(4)-glycosylated L-asparagine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_59108 UBERON:0002523 biolink:AnatomicalEntity tunica intima The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. go-plus.json Bichat's tunic|intima|tunica intima vasorum http://purl.obolibrary.org/obo/UBERON_0002523 CHEBI:59107 biolink:ChemicalSubstance EC 3.4.24.* (metalloendopeptidase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_59107 CHEBI:35131 biolink:ChemicalSubstance aldose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35131 CHEBI:50770 biolink:ChemicalSubstance N,N-dihydroxypentahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50770 CHEBI:35133 biolink:ChemicalSubstance ketoheptose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35133 CHEBI:35132 biolink:ChemicalSubstance ketose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35132 CHEBI:50765 biolink:ChemicalSubstance N,N-dihydroxyhexahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50765 UBERON:0002507 biolink:AnatomicalEntity abdominal lymph node A lymph node that is part of an abdomen [Automatically generated definition]. go-plus.json parietal abdominal lymph node|abdomen lymph node|lymph node of abdomen http://purl.obolibrary.org/obo/UBERON_0002507 CHEBI:50764 biolink:ChemicalSubstance N-hydroxyhexahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50764 CHEBI:50763 biolink:ChemicalSubstance N-hydroxypentahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50763 UBERON:0002509 biolink:AnatomicalEntity mesenteric lymph node The lymph nodes located in the mesentery, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group. go-plus.json mesenteric node|nodi lymphoidei mesenterici http://purl.obolibrary.org/obo/UBERON_0002509 CHEBI:50762 biolink:ChemicalSubstance N-hydroxytetrahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50762 CHEBI:74755 biolink:ChemicalSubstance aclacinomycin T(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74755 CHEBI:50769 biolink:ChemicalSubstance N,N-dihydroxytetrahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50769 CHEBI:50768 biolink:ChemicalSubstance N,N-dihydroxytrihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50768 UBERON:0002506 biolink:AnatomicalEntity iris epithelium An epithelium that is part of a iris [Automatically generated definition]. go-plus.json epithelial tissue of iris|iris pigmented epithelium|epithelium of iris|epithelium pigmentosum iridis|epithelium pigmentosum (iris)|iris epithelial tissue|pigmented epithelium of iris|iris epithelium http://purl.obolibrary.org/obo/UBERON_0002506 CHEBI:50767 biolink:ChemicalSubstance N,N-dihydroxydihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50767 CHEBI:50766 biolink:ChemicalSubstance N,N-dihydroxy-alpha-amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50766 CHEBI:49770 biolink:ChemicalSubstance methyl red go-plus.json http://purl.obolibrary.org/obo/CHEBI_49770 CHEBI:60111 biolink:ChemicalSubstance N(5)-[amino(hydroxyimino)methyl]-L-ornithine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60111 CHEBI:60110 biolink:ChemicalSubstance 1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60110 chebi_ph7_3 CHEBI:35146 biolink:ChemicalSubstance (S)-3-methyl-2-oxovalerate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35146 chebi_ph7_3 CHEBI:60113 biolink:ChemicalSubstance (R)-nipecotamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60113 CHEBI:35145 biolink:ChemicalSubstance D-glucuronic acid 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35145 CHEBI:35148 biolink:ChemicalSubstance (6'S)-beta,epsilon-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35148 chebi_ph7_3 CHEBI:60115 biolink:ChemicalSubstance (S)-nipecotamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60115 CHEBI:60114 biolink:ChemicalSubstance alpha,alpha-trehalose-2-sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60114 CHEBI:35147 biolink:ChemicalSubstance (6'R)-beta,epsilon-carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35147 chebi_ph7_3 CHEBI:60117 biolink:ChemicalSubstance trehalose sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60117 CHEBI:60116 biolink:ChemicalSubstance nipecotamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60116 CHEBI:60119 biolink:ChemicalSubstance sphingosine 1-phosphate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60119 chebi_ph7_3 CHEBI:60118 biolink:ChemicalSubstance (R)-nipecotamide(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60118 chebi_ph7_3 UBERON:0002511 biolink:AnatomicalEntity trabecula carnea the supporting bundles of muscular fibers lining the walls of the ventricles of the heart go-plus.json trabeculae carneae cordis|ventricle trabecula carnea|heart trabecula|trabecula of heart|ventricular trabecula|columnae carneae|cardiac trabecula|trabeculae carneae http://purl.obolibrary.org/obo/UBERON_0002511 UBERON:0002513 biolink:AnatomicalEntity endochondral bone Replacement bone that forms within cartilage. go-plus.json cartilaginous bone|endochondral bones|ossified chondrogenic bone http://purl.obolibrary.org/obo/UBERON_0002513 CHEBI:50761 biolink:ChemicalSubstance N-hydroxytrihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50761 CHEBI:35142 biolink:ChemicalSubstance aldotriose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35142 CHEBI:11152 biolink:ChemicalSubstance 1,2-didecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_11152 chebi_ph7_3 CHEBI:50760 biolink:ChemicalSubstance N-hydroxy-alpha-amino-acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50760 CHEBI:74752 biolink:ChemicalSubstance thiophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_74752 chebi_ph7_3 CHEBI:35143 biolink:ChemicalSubstance hemoglobin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35143 CHEBI:50754 biolink:ChemicalSubstance cyclohexanecarboxylate ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_50754 CHEBI:25798 biolink:ChemicalSubstance oxopentanoates go-plus.json http://purl.obolibrary.org/obo/CHEBI_25798 CHEBI:50753 biolink:ChemicalSubstance isoflavonoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50753 CHEBI:74764 biolink:ChemicalSubstance Cys-tRNA(Sec) polyanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_74764 CHEBI:50751 biolink:ChemicalSubstance anti-estrogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_50751 CHEBI:74769 biolink:ChemicalSubstance 2-methyladenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74769 CHEBI:50758 biolink:ChemicalSubstance N-hydroxydihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50758 CHEBI:25799 biolink:ChemicalSubstance oxopentanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25799 GO:0046503 biolink:BiologicalProcess glycerolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone. go-plus.json glycerolipid catabolism|glycerolipid degradation|glycerolipid breakdown http://purl.obolibrary.org/obo/GO_0046503 GO:0046502 biolink:BiologicalProcess uroporphyrinogen III metabolic process The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds. go-plus.json uroporphyrinogen III metabolism http://purl.obolibrary.org/obo/GO_0046502 GO:0046501 biolink:BiologicalProcess protoporphyrinogen IX metabolic process The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation. go-plus.json protoporphyrinogen IX metabolism http://purl.obolibrary.org/obo/GO_0046501 GO:0046500 biolink:BiologicalProcess S-adenosylmethionine metabolic process The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. go-plus.json S-adenosyl methionine metabolic process|S-adenosylmethionine metabolism|SAM metabolic process|S-adenosyl methionine metabolism http://purl.obolibrary.org/obo/GO_0046500 CHEBI:50759 biolink:ChemicalSubstance N-formyl amino acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50759 CHEBI:60120 biolink:ChemicalSubstance (R)-nipecotic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60120 chebi_ph7_3 CHEBI:35113 biolink:ChemicalSubstance elemental mercury go-plus.json http://purl.obolibrary.org/obo/CHEBI_35113 GO:0046509 biolink:MolecularActivity 1,2-diacylglycerol 3-beta-galactosyltransferase activity Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP. EC:2.4.1.46|RHEA:14945|KEGG_REACTION:R02691|MetaCyc:2.4.1.46-RXN go-plus.json UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity|MGDG synthase activity|1-beta-MGDG activity|uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity|UDP galactose-1,2-diacylglycerol galactosyltransferase activity|UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity|UDP-galactose:diacylglycerol galactosyltransferase activity|1beta-MGDG|monogalactosyldiacylglycerol synthase activity|UDP-galactose-diacylglyceride galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0046509 CHEBI:35115 biolink:ChemicalSubstance elemental manganese go-plus.json http://purl.obolibrary.org/obo/CHEBI_35115 GO:0046508 biolink:MolecularActivity hydrolase activity, acting on carbon-sulfur bonds Catalysis of the hydrolysis of any carbon-sulfur bond, C-S. EC:3.13.-.- go-plus.json hydrolase activity, acting on carbon-sulphur bonds http://purl.obolibrary.org/obo/GO_0046508 CHEBI:35114 biolink:ChemicalSubstance 3-isopropylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35114 GO:0046507 biolink:MolecularActivity UDPsulfoquinovose synthase activity Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose. MetaCyc:RXN-1223|KEGG_REACTION:R05775|RHEA:13197|EC:3.13.1.1 go-plus.json UDPsulphoquinovose synthase activity|UDP-sulfoquinovose synthase activity|UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity|sulfite:UDP-glucose sulfotransferase activity http://purl.obolibrary.org/obo/GO_0046507 GO:0046506 biolink:BiologicalProcess sulfolipid biosynthetic process The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid. go-plus.json sulfolipid anabolism|sulfolipid biosynthesis|sulfolipid synthesis|sulfolipid formation|sulpholipid biosynthetic process|sulpholipid biosynthesis http://purl.obolibrary.org/obo/GO_0046506 GO:0046505 biolink:BiologicalProcess sulfolipid metabolic process The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid. go-plus.json sulfolipid metabolism|sulpholipid metabolism|sulpholipid metabolic process http://purl.obolibrary.org/obo/GO_0046505 CHEBI:60129 biolink:ChemicalSubstance (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60129 chebi_ph7_3 GO:0046504 biolink:BiologicalProcess glycerol ether biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. go-plus.json glycerol ether anabolism|glycerol ether synthesis|glycerol ether formation|glycerol ether biosynthesis http://purl.obolibrary.org/obo/GO_0046504 CHEBI:50750 biolink:ChemicalSubstance EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50750 CHEBI:74778 biolink:ChemicalSubstance N(4)-methylcytidine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74778 CHEBI:74777 biolink:ChemicalSubstance N(4)-methylcytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74777 CHEBI:50746 biolink:ChemicalSubstance N(6)-dihydrolipoyl-L-lysine residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_50746 CHEBI:50745 biolink:ChemicalSubstance progestogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_50745 GO:0046514 biolink:BiologicalProcess ceramide catabolic process The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid. go-plus.json ceramide catabolism|ceramide degradation|ceramide breakdown http://purl.obolibrary.org/obo/GO_0046514 GO:0046513 biolink:BiologicalProcess ceramide biosynthetic process The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid. go-plus.json ceramide anabolism|ceramide synthesis|ceramide formation|ceramide biosynthesis http://purl.obolibrary.org/obo/GO_0046513 GO:0046512 biolink:BiologicalProcess sphingosine biosynthetic process The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. go-plus.json sphingosine biosynthesis|sphingosine anabolism|sphingosine synthesis|sphingosine formation http://purl.obolibrary.org/obo/GO_0046512 CHEBI:50748 biolink:ChemicalSubstance antipsoriatic go-plus.json http://purl.obolibrary.org/obo/CHEBI_50748 GO:0046511 biolink:BiologicalProcess sphinganine biosynthetic process The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol. go-plus.json sphinganine anabolism|dihydrosphingosine biosynthetic process|dihydrosphingosine biosynthesis|sphinganine synthesis|sphinganine biosynthesis|sphinganine formation http://purl.obolibrary.org/obo/GO_0046511 GO:0046510 biolink:MolecularActivity UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP. MetaCyc:RXN-1224|RHEA:49468 go-plus.json UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity|sulfolipid synthase http://purl.obolibrary.org/obo/GO_0046510 CHEBI:60131 biolink:ChemicalSubstance (1S,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60131 chebi_ph7_3 CHEBI:49751 biolink:ChemicalSubstance D-monapterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_49751 chebi_ph7_3 GO:0046519 biolink:BiologicalProcess sphingoid metabolic process The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. go-plus.json sphingoid base metabolic process|sphingoid metabolism|sphingoid base metabolism http://purl.obolibrary.org/obo/GO_0046519 GO:0046518 biolink:BiologicalProcess octamethylcyclotetrasiloxane metabolic process The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom. go-plus.json octamethylcyclotetrasiloxane metabolism http://purl.obolibrary.org/obo/GO_0046518 CHEBI:35128 biolink:ChemicalSubstance (2S)-2-isopropylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35128 GO:0046517 biolink:BiologicalProcess octamethylcyclotetrasiloxane catabolic process The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom. go-plus.json octamethylcyclotetrasiloxane degradation|octamethylcyclotetrasiloxane breakdown|octamethylcyclotetrasiloxane catabolism http://purl.obolibrary.org/obo/GO_0046517 GO:0046516 biolink:BiologicalProcess hypusine metabolic process The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine. go-plus.json hypusine metabolism http://purl.obolibrary.org/obo/GO_0046516 GO:0046515 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046515 CHEBI:74770 biolink:ChemicalSubstance 2-methyladenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74770 CHEBI:74771 biolink:ChemicalSubstance N(3)-methyluridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74771 CHEBI:11173 biolink:ChemicalSubstance 1,4-dihydroxy-2-naphthoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11173 chebi_ph7_3 CHEBI:35121 biolink:ChemicalSubstance (2R,3S)-3-isopropylmalate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35121 chebi_ph7_3 CHEBI:74773 biolink:ChemicalSubstance N(3)-methyluridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74773 CHEBI:74787 biolink:ChemicalSubstance 8-methyladenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74787 CHEBI:74786 biolink:ChemicalSubstance N(2),N(2)-dimethylguanosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74786 CHEBI:74788 biolink:ChemicalSubstance 8-methyladenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74788 UBERON:0002559 biolink:AnatomicalEntity medullary reticular formation The reticular formation is a series of brain nuclei located in the medulla oblongata go-plus.json reticular formation of medulla|reticular formation of medulla oblongata|medulla oblonmgata reticular formation|reticular formation of metepencephalon|medullary reticular nucleus|bulbar reticular formation|formatio reticularis myelencephali|medulla oblongata reticular formation|rhombencephalic reticular formation|reticular formation|metepencephalon reticular formation|reticular formation of bulb|reticular formation of medulla oblonmgata|bulb reticular formation http://purl.obolibrary.org/obo/UBERON_0002559 CHEBI:49747 biolink:ChemicalSubstance methylmercury(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49747 UBERON:0002558 biolink:AnatomicalEntity organ cavity go-plus.json cavity of organ http://purl.obolibrary.org/obo/UBERON_0002558 CHEBI:50733 biolink:ChemicalSubstance nutraceutical go-plus.json http://purl.obolibrary.org/obo/CHEBI_50733 GO:0046525 biolink:MolecularActivity xylosylprotein 4-beta-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein. Reactome:R-HSA-1889981|Reactome:R-HSA-3560804|MetaCyc:2.4.1.133-RXN|RHEA:15297|EC:2.4.1.133 go-plus.json uridine diphosphogalactose-xylose galactosyltransferase activity|UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity|UDP-D-galactose:xylose galactosyltransferase activity|UDP-galactose:xylose galactosyltransferase activity|galactosyltransferase I activity|UDP-D-galactose:D-xylose galactosyltransferase activity|UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0046525 GO:0046524 biolink:MolecularActivity sucrose-phosphate synthase activity Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate. EC:2.4.1.14|MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN|RHEA:22172 go-plus.json UDPglucose-fructose-phosphate glucosyltransferase activity|SPS|sucrose phosphate synthetase activity|uridine diphosphoglucose-fructose phosphate glucosyltransferase activity|sucrose 6-phosphate synthase activity|sucrose phosphate-uridine diphosphate glucosyltransferase activity|sucrosephosphate-UDP glucosyltransferase activity|UDP-glucose-fructose-phosphate glucosyltransferase activity|UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity|UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity http://purl.obolibrary.org/obo/GO_0046524 GO:0046523 biolink:MolecularActivity S-methyl-5-thioribose-1-phosphate isomerase activity Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate. Reactome:R-HSA-1237096|EC:5.3.1.23|RHEA:19989|KEGG_REACTION:R04420|Reactome:R-HSA-1299507|MetaCyc:5.3.1.23-RXN go-plus.json S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|5-methylthioribose-1-phosphate isomerase activity|S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity|5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|methylthioribose 1-phosphate isomerase activity|MTR-1-P isomerase activity|1-phospho-5'-S-methylthioribose isomerase activity|1-PMTR isomerase activity http://purl.obolibrary.org/obo/GO_0046523 GO:0046522 biolink:MolecularActivity S-methyl-5-thioribose kinase activity Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+). MetaCyc:5-METHYLTHIORIBOSE-KINASE-RXN|RHEA:22312|KEGG_REACTION:R04143|EC:2.7.1.100 go-plus.json 5-methylthioribose kinase activity|ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity|5-methylthioribose kinase (phosphorylating)|ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity|methylthioribose kinase activity|MTR kinase activity http://purl.obolibrary.org/obo/GO_0046522 CHEBI:84107 biolink:ChemicalSubstance 1-O-(4-oxoretinoyl)-beta-D-glucuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84107 GO:0046521 biolink:BiologicalProcess sphingoid catabolic process The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. go-plus.json sphingoid breakdown|sphingoid catabolism|sphingoid degradation http://purl.obolibrary.org/obo/GO_0046521 GO:0046520 biolink:BiologicalProcess sphingoid biosynthetic process The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. go-plus.json sphingoid anabolism|sphingoid synthesis|sphingoid formation|sphingoid biosynthesis http://purl.obolibrary.org/obo/GO_0046520 CHEBI:84105 biolink:ChemicalSubstance ketoretinoic acid glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_84105 GO:0046529 biolink:BiologicalProcess imaginal disc fusion, thorax closure The joining of the parts of the wing imaginal discs, giving rise to the adult thorax. go-plus.json http://purl.obolibrary.org/obo/GO_0046529 GO:0046528 biolink:BiologicalProcess imaginal disc fusion The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0046528 GO:0046527 biolink:MolecularActivity glucosyltransferase activity Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. go-plus.json http://purl.obolibrary.org/obo/GO_0046527 GO:0046526 biolink:MolecularActivity D-xylulose reductase activity Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH. Reactome:R-HSA-5662471|RHEA:20433|KEGG_REACTION:R01896|EC:1.1.1.9|MetaCyc:D-XYLULOSE-REDUCTASE-RXN go-plus.json xylitol dehydrogenase activity http://purl.obolibrary.org/obo/GO_0046526 CHEBI:74781 biolink:ChemicalSubstance 5-carboxymethylaminomethyluridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74781 CHEBI:74783 biolink:ChemicalSubstance astringent go-plus.json http://purl.obolibrary.org/obo/CHEBI_74783 UBERON:0002561 biolink:AnatomicalEntity lumen of central nervous system The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube go-plus.json neuraxis lumen|neuraxis cavity|cavity of neuraxis|cavity of ventricular system of neuraxis http://purl.obolibrary.org/obo/UBERON_0002561 CHEBI:74782 biolink:ChemicalSubstance 5-carboxymethylaminomethyluridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74782 CHEBI:74785 biolink:ChemicalSubstance 5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74785 CHEBI:74784 biolink:ChemicalSubstance 5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74784 UBERON:0002548 biolink:AnatomicalEntity larva A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. go-plus.json veliger|planula|ammocoete|nymph|maggot|naiad|grub|glochidium|leptocephalus|trochophore|zoea|tadpole|caterpillar|wriggler|bipinnaria|larval organism http://purl.obolibrary.org/obo/UBERON_0002548 CHEBI:50725 biolink:ChemicalSubstance 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_50725 CHEBI:25789 biolink:ChemicalSubstance hexenedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25789 CHEBI:50723 biolink:ChemicalSubstance (Z)-phenylacetaldehyde oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_50723 chebi_ph7_3 UBERON:6003006 biolink:AnatomicalEntity adult segment Segment of the adult. go-plus.json http://purl.obolibrary.org/obo/UBERON_6003006 GO:0046536 biolink:CellularComponent dosage compensation complex A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes. go-plus.json http://purl.obolibrary.org/obo/GO_0046536 goslim_pir GO:0046535 biolink:BiologicalProcess detection of chemical stimulus involved in sensory perception of umami taste The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. go-plus.json umami taste detection|perception of umami taste, sensory transduction of chemical stimulus|perception of umami taste, detection of chemical stimulus|sensory transduction of umami taste|sensory detection of chemical stimulus during perception of umami taste|sensory detection of umami taste|sensory transduction of chemical stimulus during perception of umami taste http://purl.obolibrary.org/obo/GO_0046535 UBERON:6003005 biolink:AnatomicalEntity insect adult tagma Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004). go-plus.json http://purl.obolibrary.org/obo/UBERON_6003005 GO:0046534 biolink:BiologicalProcess positive regulation of photoreceptor cell differentiation Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. go-plus.json stimulation of photoreceptor cell differentiation|up-regulation of photoreceptor cell differentiation|activation of photoreceptor cell differentiation|up regulation of photoreceptor differentiation|positive regulation of photoreceptor differentiation|activation of photoreceptor differentiation|stimulation of photoreceptor differentiation|up regulation of photoreceptor cell differentiation|up-regulation of photoreceptor differentiation|upregulation of photoreceptor cell differentiation|upregulation of photoreceptor differentiation http://purl.obolibrary.org/obo/GO_0046534 CHEBI:60151 biolink:ChemicalSubstance oxidised LDL go-plus.json http://purl.obolibrary.org/obo/CHEBI_60151 CHEBI:50726 biolink:ChemicalSubstance CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_50726 CHEBI:84118 biolink:ChemicalSubstance ganglioside GM3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84118 GO:0046533 biolink:BiologicalProcess negative regulation of photoreceptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. go-plus.json down regulation of photoreceptor differentiation|downregulation of photoreceptor differentiation|down-regulation of photoreceptor cell differentiation|down-regulation of photoreceptor differentiation|negative regulation of photoreceptor differentiation|inhibition of photoreceptor differentiation|downregulation of photoreceptor cell differentiation|down regulation of photoreceptor cell differentiation|inhibition of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046533 GO:0046532 biolink:BiologicalProcess regulation of photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. go-plus.json regulation of photoreceptor differentiation http://purl.obolibrary.org/obo/GO_0046532 CHEBI:60152 biolink:ChemicalSubstance beta-D-Galp-(1->4)-D-GlcpNAc go-plus.json http://purl.obolibrary.org/obo/CHEBI_60152 chebi_ph7_3 GO:0046531 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046531 UBERON:6003009 biolink:AnatomicalEntity insect adult head segment Segment of the adult head. go-plus.json http://purl.obolibrary.org/obo/UBERON_6003009 CHEBI:25781 biolink:ChemicalSubstance hex-2-enedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25781 GO:0046530 biolink:BiologicalProcess photoreceptor cell differentiation The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0046530 UBERON:6003007 biolink:AnatomicalEntity insect adult head Head of the adult organism. go-plus.json http://purl.obolibrary.org/obo/UBERON_6003007 CHEBI:84114 biolink:ChemicalSubstance D-leucine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84114 CHEBI:84113 biolink:ChemicalSubstance D-isoleucine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84113 CHEBI:84111 biolink:ChemicalSubstance L-isoleucine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84111 CHEBI:60158 biolink:ChemicalSubstance (E)-4,8-dimethyl-1,3,7-nonatriene go-plus.json http://purl.obolibrary.org/obo/CHEBI_60158 chebi_ph7_3 CHEBI:35106 biolink:ChemicalSubstance nitrogen hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_35106 GO:0046539 biolink:MolecularActivity histamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+). RHEA:19301|MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R02155|EC:2.1.1.8|Reactome:R-HSA-175993 go-plus.json S-adenosylmethionine-histamine N-methyltransferase activity|S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity|imidazolemethyltransferase activity|histamine methyltransferase activity|histamine 1-methyltransferase activity|histamine-methylating enzyme http://purl.obolibrary.org/obo/GO_0046539 GO:0046538 biolink:MolecularActivity 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate. go-plus.json PGAM-d|glycerate phosphomutase (diphosphoglycerate cofactor) activity http://purl.obolibrary.org/obo/GO_0046538 GO:0046537 biolink:MolecularActivity 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate. go-plus.json PGAM-i http://purl.obolibrary.org/obo/GO_0046537 CHEBI:35107 biolink:ChemicalSubstance azane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35107 UBERON:0002553 biolink:AnatomicalEntity anatomical cavity Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. go-plus.json cavity http://purl.obolibrary.org/obo/UBERON_0002553 CHEBI:50710 biolink:ChemicalSubstance dihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50710 CHEBI:25754 biolink:ChemicalSubstance oxo carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25754 CHEBI:25753 biolink:ChemicalSubstance oxo-5beta-cholanic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_25753 UBERON:0002537 biolink:AnatomicalEntity hermaphrodite gonad A gonad with both testicular and ovarian aspects[WP]. go-plus.json glandula hermaphroditica|hermaphrodite genitalia|hermaphrodite gland|ovotestis http://purl.obolibrary.org/obo/UBERON_0002537 CHEBI:50714 biolink:ChemicalSubstance hexahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50714 CHEBI:50713 biolink:ChemicalSubstance pentahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50713 UBERON:0002536 biolink:AnatomicalEntity arthropod sensillum Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt] go-plus.json sensillum http://purl.obolibrary.org/obo/UBERON_0002536 CHEBI:50712 biolink:ChemicalSubstance tetrahomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50712 UBERON:0002539 biolink:AnatomicalEntity pharyngeal arch One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. go-plus.json pharyngeal arches|arcus pharyngei|visceral arch|branchial arch http://purl.obolibrary.org/obo/UBERON_0002539 UBERON:0002538 biolink:AnatomicalEntity hatching gland The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process[GO]. A transversely oriented set of cells located deep to the EVL on the pericardial membrane, especially prominent during pharyngula period because of the brightly refractile cytoplasmic granules (containing hatching enzymes) of the principal cells of the gland. go-plus.json hgg|frontal gland http://purl.obolibrary.org/obo/UBERON_0002538 CHEBI:50711 biolink:ChemicalSubstance trihomomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50711 GO:0046547 biolink:MolecularActivity trans-aconitate 3-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine. KEGG_REACTION:R05764|RHEA:22200|MetaCyc:2.1.1.145-RXN|EC:2.1.1.145 go-plus.json S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity http://purl.obolibrary.org/obo/GO_0046547 CHEBI:60160 biolink:ChemicalSubstance polyester polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_60160 GO:0046546 biolink:BiologicalProcess development of primary male sexual characteristics The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0046546 GO:0046545 biolink:BiologicalProcess development of primary female sexual characteristics The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0046545 GO:0046544 biolink:BiologicalProcess development of secondary male sexual characteristics The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0046544 CHEBI:84129 biolink:ChemicalSubstance L-valine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84129 CHEBI:50715 biolink:ChemicalSubstance methylnaphthalene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50715 GO:0046543 biolink:BiologicalProcess development of secondary female sexual characteristics The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion. go-plus.json http://purl.obolibrary.org/obo/GO_0046543 CHEBI:84128 biolink:ChemicalSubstance 2-carboxyacyl CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84128 chebi_ph7_3 CHEBI:25750 biolink:ChemicalSubstance oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_25750 chebi_ph7_3 CHEBI:60164 biolink:ChemicalSubstance ionic polymer go-plus.json http://purl.obolibrary.org/obo/CHEBI_60164 GO:0046542 biolink:BiologicalProcess obsolete alpha-factor export OBSOLETE. The directed movement of alpha-factor, one of the two yeast mating factors, out of a cell. go-plus.json alpha-factor export http://purl.obolibrary.org/obo/GO_0046542 CHEBI:84127 biolink:ChemicalSubstance 2-carboxyacyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84127 GO:0046541 biolink:BiologicalProcess saliva secretion The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin. Wikipedia:Salivation go-plus.json salivation http://purl.obolibrary.org/obo/GO_0046541 GO:0046540 biolink:CellularComponent U4/U6 x U5 tri-snRNP complex A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs. go-plus.json U4/U6.U5 snRNP complex http://purl.obolibrary.org/obo/GO_0046540 CHEBI:84124 biolink:ChemicalSubstance D-tyrosine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84124 CHEBI:84123 biolink:ChemicalSubstance advanced glycation end-product go-plus.json http://purl.obolibrary.org/obo/CHEBI_84123 GO:0071509 biolink:BiologicalProcess obsolete activation of MAPKK activity involved in conjugation with cellular fusion OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion. go-plus.json activation of MAP kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAPKK activity|conjugation with cellular fusion, activation of MAP kinase kinase activity|activation of MAPKK activity involved in mating response http://purl.obolibrary.org/obo/GO_0071509 CHEBI:84122 biolink:ChemicalSubstance D-methionine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84122 GO:0071508 biolink:BiologicalProcess obsolete activation of MAPK activity involved in conjugation with cellular fusion OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion. go-plus.json activation of MAPK activity involved in mating response|conjugation with cellular fusion, activation of MAPK activity http://purl.obolibrary.org/obo/GO_0071508 CHEBI:84121 biolink:ChemicalSubstance L-methionine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84121 CHEBI:60169 biolink:ChemicalSubstance phosphatidylinositol trisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60169 GO:0071507 biolink:BiologicalProcess pheromone response MAPK cascade A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion. go-plus.json MAPK signaling in response to pheromone|MAPKKK cascade involved in conjugation with cellular fusion|conjugation with cellular fusion, MAPKKK cascade|MAPKKK cascade involved in mating response|Fus3 signaling cascade|MAPK cascade involved in conjugation with cellular fusion|pheromone MAPK module http://purl.obolibrary.org/obo/GO_0071507 GO:0071506 biolink:BiologicalProcess cellular response to mycophenolic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus. go-plus.json cellular response to mycophenolate http://purl.obolibrary.org/obo/GO_0071506 GO:0046549 biolink:BiologicalProcess retinal cone cell development Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. go-plus.json http://purl.obolibrary.org/obo/GO_0046549 GO:0071505 biolink:BiologicalProcess response to mycophenolic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus. go-plus.json response to mycophenolate http://purl.obolibrary.org/obo/GO_0071505 GO:0046548 biolink:BiologicalProcess retinal rod cell development Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. go-plus.json http://purl.obolibrary.org/obo/GO_0046548 GO:0071504 biolink:BiologicalProcess cellular response to heparin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071504 UBERON:0002544 biolink:AnatomicalEntity digit A subdivision of the autopod that has as part a series of phalanges together with associated vasculature, musculature, integument and nerves. It is continuous with the metapodial subdivision of the autopod, but does not include the metapodials. In species such as humans, fully formed digits are distinct, whereas in other species the digits may be connected by interdigital webbing, or may be completely unseparated (for example, in cetaceans). go-plus.json digit (phalangeal portion) plus soft tissue|limb digit|acropodial unit http://purl.obolibrary.org/obo/UBERON_0002544 GO:0071503 biolink:BiologicalProcess response to heparin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071503 GO:0071502 biolink:BiologicalProcess cellular response to temperature stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. go-plus.json cellular response to thermal stimulus http://purl.obolibrary.org/obo/GO_0071502 UBERON:0002546 biolink:AnatomicalEntity cranial placode Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. go-plus.json ectodermal cranial placode|placode|ectodermal placode|cranial placodes http://purl.obolibrary.org/obo/UBERON_0002546 GO:0071501 biolink:BiologicalProcess cellular response to sterol depletion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. go-plus.json cellular sterol depletion response http://purl.obolibrary.org/obo/GO_0071501 GO:0071500 biolink:BiologicalProcess cellular response to nitrosative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. go-plus.json http://purl.obolibrary.org/obo/GO_0071500 UBERON:0002540 biolink:AnatomicalEntity lateral line system A line of sensory organs and associated structures along the sides of fish and amphibia that detect vibrations and pressure changes. go-plus.json lateral line organs|lateral line stitches|ll|lateral-line organs http://purl.obolibrary.org/obo/UBERON_0002540 UBERON:0002541 biolink:AnatomicalEntity germ ring The thickend rim of the blastoderm evident during late blastula and gastrula stages[FishBase]. Embryonic structure which is a uniform thickened annulus at the blastoderm margin, consisting of two layers in addition to the EVL, the epiblast and the hypoblast. The germ ring is formed by the involution of the blastoderm back upon itself[ZFA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0002541 GO:0046550 biolink:BiologicalProcess (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7. RESID:AA0328 go-plus.json (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine anabolism from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine synthesis from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine formation from asparagine http://purl.obolibrary.org/obo/GO_0046550 UBERON:0002529 biolink:AnatomicalEntity limb segment A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles. go-plus.json segment of limb|region of limb|subdivision of limb|limb region|extremity part|free limb segment http://purl.obolibrary.org/obo/UBERON_0002529 CHEBI:50703 biolink:ChemicalSubstance 8-(methylsulfanyl)octanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_50703 chebi_ph7_3 CHEBI:49713 biolink:ChemicalSubstance lithium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_49713 chebi_ph7_3 CHEBI:50702 biolink:ChemicalSubstance 7-(methylsulfanyl)heptanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_50702 chebi_ph7_3 CHEBI:50701 biolink:ChemicalSubstance 6-(methylsulfanyl)hexanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_50701 chebi_ph7_3 UBERON:0002527 biolink:AnatomicalEntity pancreatic lymph node A lymph node that is part of a pancreas [Automatically generated definition]. go-plus.json pyloric lymph node|aJCC level 19 node|pancreas lymph node|lymph node of pancreas|pancreatic node http://purl.obolibrary.org/obo/UBERON_0002527 CHEBI:50700 biolink:ChemicalSubstance 5-(methylsulfanyl)pentanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_50700 chebi_ph7_3 GO:0046558 biolink:MolecularActivity arabinan endo-1,5-alpha-L-arabinosidase activity Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans. MetaCyc:3.2.1.99-RXN|EC:3.2.1.99 go-plus.json endo-1,5-alpha-L-arabinanase activity|endo-alpha-1,5-arabanase activity|endo-arabanase activity|1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity http://purl.obolibrary.org/obo/GO_0046558 CHEBI:50707 biolink:ChemicalSubstance homomethionine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50707 GO:0046557 biolink:MolecularActivity glucan endo-1,6-beta-glucosidase activity Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans. MetaCyc:3.2.1.75-RXN|EC:3.2.1.75 go-plus.json beta-1,6-glucan 6-glucanohydrolase activity|beta-1->6-glucan hydrolase activity|1,6-beta-D-glucan glucanohydrolase activity|endo-(1->6)-beta-D-glucanase activity|endo-1,6-beta-D-glucanase activity|endo-(1,6)-beta-D-glucanase activity|endo-beta-1,6-glucanase activity|beta-1,6-glucanase-pustulanase activity|endo-1,6-beta-glucanase activity|beta-1,6-glucanase activity|beta-1,6-glucan hydrolase activity http://purl.obolibrary.org/obo/GO_0046557 GO:0046556 biolink:MolecularActivity alpha-L-arabinofuranosidase activity Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. EC:3.2.1.55|MetaCyc:3.2.1.55-RXN go-plus.json alpha-L-arabinosidase activity|alpha-arabinofuranosidase activity|alpha-arabinosidase activity|alpha-N-arabinofuranosidase activity|polysaccharide alpha-L-arabinofuranosidase activity|alpha-L-arabinofuranoside hydrolase activity|arabinofuranosidase activity|L-arabinosidase activity|arabinosidase activity|alpha-L-arabinanase activity|alpha-L-arabinofuranoside arabinofuranohydrolase activity http://purl.obolibrary.org/obo/GO_0046556 CHEBI:60173 biolink:ChemicalSubstance purine deoxyribonucleoside go-plus.json http://purl.obolibrary.org/obo/CHEBI_60173 GO:0046555 biolink:MolecularActivity acetylxylan esterase activity Catalysis of the deacetylation of xylans and xylo-oligosaccharides. MetaCyc:3.1.1.72-RXN|EC:3.1.1.72 go-plus.json http://purl.obolibrary.org/obo/GO_0046555 CHEBI:50704 biolink:ChemicalSubstance 9-(methylsulfanyl)nonanal oxime go-plus.json http://purl.obolibrary.org/obo/CHEBI_50704 chebi_ph7_3 CHEBI:84139 biolink:ChemicalSubstance myo-inositol phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84139 chebi_ph7_3 GO:0046554 biolink:MolecularActivity malate dehydrogenase (NADP+) activity Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+. RHEA:10824|EC:1.1.1.82|KEGG_REACTION:R00343|MetaCyc:MALATE-DEHYDROGENASE-NADP+-RXN go-plus.json malate NADP dehydrogenase activity|NADP-malate dehydrogenase activity|(S)-malate:NADP+ oxidoreductase activity|NADP-linked malate dehydrogenase activity|malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)|NADP malate dehydrogenase activity http://purl.obolibrary.org/obo/GO_0046554 CHEBI:60175 biolink:ChemicalSubstance 5-hydroxylysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60175 CHEBI:60174 biolink:ChemicalSubstance rhamnogalacturonan I go-plus.json http://purl.obolibrary.org/obo/CHEBI_60174 CHEBI:84138 biolink:ChemicalSubstance (3R)-3,6-diammoniohexanoate(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84138 chebi_ph7_3 GO:0046553 biolink:MolecularActivity D-malate dehydrogenase (decarboxylating) activity Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate. KEGG_REACTION:R00215|EC:1.1.1.83|RHEA:18365|MetaCyc:1.1.1.83-RXN go-plus.json D-malate dehydrogenase activity|D-malic enzyme|(R)-malate:NAD+ oxidoreductase (decarboxylating)|bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating) http://purl.obolibrary.org/obo/GO_0046553 GO:0046552 biolink:BiologicalProcess photoreceptor cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. go-plus.json http://purl.obolibrary.org/obo/GO_0046552 GO:0046551 biolink:BiologicalProcess retinal cone cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye. go-plus.json http://purl.obolibrary.org/obo/GO_0046551 CHEBI:84135 biolink:ChemicalSubstance L-serine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84135 CHEBI:84133 biolink:ChemicalSubstance D-serine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84133 GO:0046559 biolink:MolecularActivity alpha-glucuronidase activity Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate. RHEA:20005|MetaCyc:3.2.1.139-RXN|EC:3.2.1.139 go-plus.json alpha-glucosiduronase activity|alpha-D-glucosiduronate glucuronohydrolase activity http://purl.obolibrary.org/obo/GO_0046559 UBERON:0002533 biolink:AnatomicalEntity post-anal tail bud The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node. go-plus.json end bud|tail bud mesenchyme|tailbud|tail bud http://purl.obolibrary.org/obo/UBERON_0002533 UBERON:0002532 biolink:AnatomicalEntity epiblast (generic) In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA] go-plus.json epiblast|ectoblast|epiblastus|blastocyst|primitive ectoderm http://purl.obolibrary.org/obo/UBERON_0002532 UBERON:0002534 biolink:AnatomicalEntity paired fin Fin that is one of a pair located ventrally on the organism. go-plus.json pelvic/pectoral fin http://purl.obolibrary.org/obo/UBERON_0002534 UBERON:0002531 biolink:AnatomicalEntity paired fin bud An outgrowth on the lateral trunk of the embryo that develops into a paired fin. The fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. go-plus.json fin bud|fin buds http://purl.obolibrary.org/obo/UBERON_0002531 UBERON:0002530 biolink:AnatomicalEntity gland an organ that functions as a secretory or excretory organ go-plus.json glandula|glandular organ|Druese http://purl.obolibrary.org/obo/UBERON_0002530 CHEBI:59193 biolink:ChemicalSubstance 2-iminio-3-(indol-3-yl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59193 chebi_ph7_3 CHEBI:59174 biolink:ChemicalSubstance hapten go-plus.json http://purl.obolibrary.org/obo/CHEBI_59174 NCBITaxon:117565 biolink:OrganismalEntity Myxini go-plus.json fish|Hyperotreti|Agnatha|fishes http://purl.obolibrary.org/obo/NCBITaxon_117565 CHEBI:142439 biolink:ChemicalSubstance alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer go-plus.json http://purl.obolibrary.org/obo/CHEBI_142439 CHEBI:59163 biolink:ChemicalSubstance biomarker go-plus.json http://purl.obolibrary.org/obo/CHEBI_59163 CHEBI:35193 biolink:ChemicalSubstance tetraterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35193 CHEBI:35192 biolink:ChemicalSubstance sesterterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35192 CHEBI:35195 biolink:ChemicalSubstance surfactant go-plus.json http://purl.obolibrary.org/obo/CHEBI_35195 CHEBI:35194 biolink:ChemicalSubstance isoprene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35194 chebi_ph7_3 CHEBI:35196 biolink:ChemicalSubstance nitrogen oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35196 CHEBI:528881 biolink:ChemicalSubstance (9Z,12Z,15Z)-octadeca-9,12,15-trienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_528881 CHEBI:142422 biolink:ChemicalSubstance gamma-carboxy-L-glutamate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142422 NCBITaxon:117569 biolink:OrganismalEntity Hyperoartia go-plus.json fishes|Monorhina|fish|Cephalaspidomorphi|Agnatha http://purl.obolibrary.org/obo/NCBITaxon_117569 NCBITaxon:117571 biolink:OrganismalEntity Euteleostomi go-plus.json Osteichthyes|bony vertebrates http://purl.obolibrary.org/obo/NCBITaxon_117571 NCBITaxon:117570 biolink:OrganismalEntity Teleostomi go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_117570 CHEBI:142410 biolink:ChemicalSubstance guanosine 3'-diphosphate 5'-triphosphate hexaanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142410 chebi_ph7_3 CHEBI:35179 biolink:ChemicalSubstance 2-oxo monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35179 chebi_ph7_3 CHEBI:59140 biolink:ChemicalSubstance precorrin carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59140 CHEBI:35171 biolink:ChemicalSubstance elemental vanadium go-plus.json http://purl.obolibrary.org/obo/CHEBI_35171 CHEBI:35173 biolink:ChemicalSubstance 2-dehydro-3-deoxy-L-arabinonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35173 chebi_ph7_3 CHEBI:35172 biolink:ChemicalSubstance vanadium cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_35172 chebi_ph7_3 CHEBI:35175 biolink:ChemicalSubstance sulfate salt go-plus.json http://purl.obolibrary.org/obo/CHEBI_35175 CHEBI:35177 biolink:ChemicalSubstance 2-oxohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35177 chebi_ph7_3 CHEBI:35191 biolink:ChemicalSubstance triterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35191 CHEBI:35190 biolink:ChemicalSubstance diterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35190 CHEBI:142409 biolink:ChemicalSubstance S-alkyl-L-cysteine S-oxide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142409 chebi_ph7_3 CHEBI:35189 biolink:ChemicalSubstance sesquiterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35189 CHEBI:142408 biolink:ChemicalSubstance arylkylammonium go-plus.json http://purl.obolibrary.org/obo/CHEBI_142408 chebi_ph7_3 CHEBI:59132 biolink:ChemicalSubstance antigen go-plus.json http://purl.obolibrary.org/obo/CHEBI_59132 CHEBI:35181 biolink:ChemicalSubstance 4-amino-4-deoxychorismate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35181 CHEBI:35184 biolink:ChemicalSubstance gluconic acid phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35184 CHEBI:59139 biolink:ChemicalSubstance gibberellin carboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59139 CHEBI:35186 biolink:ChemicalSubstance terpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35186 CHEBI:59138 biolink:ChemicalSubstance (8S)-cinchonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_59138 CHEBI:59137 biolink:ChemicalSubstance (8xi)-cinchonan go-plus.json http://purl.obolibrary.org/obo/CHEBI_59137 CHEBI:35188 biolink:ChemicalSubstance hemiterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35188 CHEBI:35187 biolink:ChemicalSubstance monoterpene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35187 CHEBI:74721 biolink:ChemicalSubstance N(2)-methylguanosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74721 CHEBI:74720 biolink:ChemicalSubstance N(7)-methylguanosine 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74720 CHEBI:74722 biolink:ChemicalSubstance N(2)-methylguanosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74722 CHEBI:74725 biolink:ChemicalSubstance 5-methylcytidine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74725 CHEBI:74724 biolink:ChemicalSubstance 5-methylcytidine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74724 CHEBI:35157 biolink:ChemicalSubstance aldoheptose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35157 CHEBI:35159 biolink:ChemicalSubstance ribose monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35159 CHEBI:35158 biolink:ChemicalSubstance ribose bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35158 CHEBI:50793 biolink:ChemicalSubstance 2-methyl-3-oxosuccinic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50793 CHEBI:35155 biolink:ChemicalSubstance elemental calcium go-plus.json http://purl.obolibrary.org/obo/CHEBI_35155 CHEBI:50787 biolink:ChemicalSubstance L-erythro-3-methylmalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50787 CHEBI:74731 biolink:ChemicalSubstance N(3)-methylpseudouridine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74731 CHEBI:50786 biolink:ChemicalSubstance anabolic androgenic steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_50786 CHEBI:74736 biolink:ChemicalSubstance N(1)-methyladenosine 5'-monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_74736 CHEBI:74735 biolink:ChemicalSubstance N(1)-methyladenosine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74735 CHEBI:50789 biolink:ChemicalSubstance (3S)-3-hydroxy-L-asparagine go-plus.json http://purl.obolibrary.org/obo/CHEBI_50789 CHEBI:35168 biolink:ChemicalSubstance hydrogenvanadate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35168 CHEBI:35169 biolink:ChemicalSubstance dihydrogenvanadate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35169 chebi_ph7_3 CHEBI:35160 biolink:ChemicalSubstance phosphomethylribose go-plus.json http://purl.obolibrary.org/obo/CHEBI_35160 CHEBI:35162 biolink:ChemicalSubstance acyclic carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35162 CHEBI:35161 biolink:ChemicalSubstance deoxyketopentose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35161 CHEBI:50783 biolink:ChemicalSubstance ent-isokaurene go-plus.json http://purl.obolibrary.org/obo/CHEBI_50783 chebi_ph7_3 CHEBI:35164 biolink:ChemicalSubstance 2,4'-dihydroxyacetophenone go-plus.json http://purl.obolibrary.org/obo/CHEBI_35164 chebi_ph7_3 CHEBI:35163 biolink:ChemicalSubstance cyclic carotene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35163 CHEBI:35166 biolink:ChemicalSubstance vanadium coordination entity go-plus.json http://purl.obolibrary.org/obo/CHEBI_35166 CHEBI:50781 biolink:ChemicalSubstance EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_50781 CHEBI:74730 biolink:ChemicalSubstance N(3)-methylpseudouridine 5'-monophosphate residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_74730 CHEBI:50780 biolink:ChemicalSubstance appetite regulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_50780 GO:0071484 biolink:BiologicalProcess cellular response to light intensity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071484 GO:0071483 biolink:BiologicalProcess cellular response to blue light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. go-plus.json cellular response to blue light stimulus http://purl.obolibrary.org/obo/GO_0071483 GO:0071482 biolink:BiologicalProcess cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. go-plus.json http://purl.obolibrary.org/obo/GO_0071482 GO:0071481 biolink:BiologicalProcess cellular response to X-ray Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). go-plus.json cellular response to X-ray radiation stimulus http://purl.obolibrary.org/obo/GO_0071481 GO:0071480 biolink:BiologicalProcess cellular response to gamma radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. go-plus.json cellular response to gamma ray|cellular response to gamma-ray photon http://purl.obolibrary.org/obo/GO_0071480 GO:1900359 biolink:BiologicalProcess positive regulation of nigerotriose transport Any process that activates or increases the frequency, rate or extent of nigerotriose transport. go-plus.json up regulation of nigerotriose transport|upregulation of nigerotriose transport|up-regulation of nigerotriose transport|activation of nigerotriose transport http://purl.obolibrary.org/obo/GO_1900359 GO:1900356 biolink:BiologicalProcess positive regulation of methanofuran metabolic process Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process. go-plus.json upregulation of methanofuran metabolic process|up-regulation of methanofuran metabolism|up-regulation of methanofuran metabolic process|activation of methanofuran metabolic process|upregulation of methanofuran metabolism|up regulation of methanofuran metabolism|positive regulation of methanofuran metabolism|up regulation of methanofuran metabolic process|activation of methanofuran metabolism http://purl.obolibrary.org/obo/GO_1900356 GO:1900355 biolink:BiologicalProcess negative regulation of methanofuran metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process. go-plus.json inhibition of methanofuran metabolic process|inhibition of methanofuran metabolism|down regulation of methanofuran metabolism|down-regulation of methanofuran metabolic process|downregulation of methanofuran metabolism|downregulation of methanofuran metabolic process|down-regulation of methanofuran metabolism|negative regulation of methanofuran metabolism|down regulation of methanofuran metabolic process http://purl.obolibrary.org/obo/GO_1900355 GO:1900358 biolink:BiologicalProcess negative regulation of nigerotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport. go-plus.json downregulation of nigerotriose transport|down regulation of nigerotriose transport|inhibition of nigerotriose transport|down-regulation of nigerotriose transport http://purl.obolibrary.org/obo/GO_1900358 GO:1900357 biolink:BiologicalProcess regulation of nigerotriose transport Any process that modulates the frequency, rate or extent of nigerotriose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900357 GO:1900352 biolink:BiologicalProcess negative regulation of methanofuran biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process. go-plus.json inhibition of methanofuran biosynthesis|down regulation of methanofuran biosynthetic process|down regulation of methanofuran biosynthesis|downregulation of methanofuran biosynthetic process|downregulation of methanofuran biosynthesis|down-regulation of methanofuran biosynthesis|negative regulation of methanofuran biosynthesis|down-regulation of methanofuran biosynthetic process|inhibition of methanofuran biosynthetic process http://purl.obolibrary.org/obo/GO_1900352 GO:1900351 biolink:BiologicalProcess regulation of methanofuran biosynthetic process Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process. go-plus.json regulation of methanofuran biosynthesis http://purl.obolibrary.org/obo/GO_1900351 GO:1900354 biolink:BiologicalProcess regulation of methanofuran metabolic process Any process that modulates the frequency, rate or extent of methanofuran metabolic process. go-plus.json regulation of methanofuran metabolism http://purl.obolibrary.org/obo/GO_1900354 GO:1900353 biolink:BiologicalProcess positive regulation of methanofuran biosynthetic process Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process. go-plus.json up-regulation of methanofuran biosynthetic process|up-regulation of methanofuran biosynthesis|upregulation of methanofuran biosynthesis|upregulation of methanofuran biosynthetic process|up regulation of methanofuran biosynthesis|up regulation of methanofuran biosynthetic process|activation of methanofuran biosynthetic process|positive regulation of methanofuran biosynthesis|activation of methanofuran biosynthesis http://purl.obolibrary.org/obo/GO_1900353 GO:1900361 biolink:BiologicalProcess negative regulation of pentasaccharide transport Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport. go-plus.json downregulation of pentasaccharide transport|down-regulation of pentasaccharide transport|inhibition of pentasaccharide transport|down regulation of pentasaccharide transport http://purl.obolibrary.org/obo/GO_1900361 GO:1900360 biolink:BiologicalProcess regulation of pentasaccharide transport Any process that modulates the frequency, rate or extent of pentasaccharide transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900360 GO:0071489 biolink:BiologicalProcess cellular response to red or far red light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json http://purl.obolibrary.org/obo/GO_0071489 GO:0071488 biolink:BiologicalProcess cellular response to very low light intensity stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec. go-plus.json http://purl.obolibrary.org/obo/GO_0071488 GO:0071487 biolink:BiologicalProcess cellular response to low light intensity stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2. go-plus.json http://purl.obolibrary.org/obo/GO_0071487 GO:0071486 biolink:BiologicalProcess cellular response to high light intensity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071486 GO:0071485 biolink:BiologicalProcess cellular response to absence of light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli. go-plus.json cellular response to darkness http://purl.obolibrary.org/obo/GO_0071485 GO:0071473 biolink:BiologicalProcess cellular response to cation stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0071473 GO:0071472 biolink:BiologicalProcess cellular response to salt stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json cellular response to ionic osmotic stress|cellular salinity response http://purl.obolibrary.org/obo/GO_0071472 GO:0071471 biolink:BiologicalProcess cellular response to non-ionic osmotic stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment. go-plus.json http://purl.obolibrary.org/obo/GO_0071471 GO:0071470 biolink:BiologicalProcess cellular response to osmotic stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json cellular osmotic stress response|cellular osmotic response http://purl.obolibrary.org/obo/GO_0071470 GO:1900367 biolink:BiologicalProcess positive regulation of defense response to insect Any process that activates or increases the frequency, rate or extent of defense response to insect. go-plus.json upregulation of defense response to insect|positive regulation of physiological defense response to insect|up regulation of physiological defense response to insect|up-regulation of defense response to insect|activation of defense response to insect|upregulation of physiological defense response to insect|up regulation of defense response to insect|up-regulation of physiological defense response to insect|activation of physiological defense response to insect http://purl.obolibrary.org/obo/GO_1900367 GO:1900366 biolink:BiologicalProcess negative regulation of defense response to insect Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. go-plus.json negative regulation of physiological defense response to insect|down-regulation of physiological defense response to insect|susceptibility to insect|downregulation of physiological defense response to insect|down regulation of physiological defense response to insect|inhibition of physiological defense response to insect|down-regulation of defense response to insect|downregulation of defense response to insect|down regulation of defense response to insect|inhibition of defense response to insect http://purl.obolibrary.org/obo/GO_1900366 GO:1900369 biolink:BiologicalProcess negative regulation of RNA interference Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference. go-plus.json downregulation of posttranscriptional gene silencing by siRNA|down-regulation of RNA interference|downregulation of RNAi|down regulation of RNAi|down-regulation of posttranscriptional gene silencing by siRNA|negative regulation of posttranscriptional gene silencing by siRNA|downregulation of RNA interference|down regulation of RNA interference|inhibition of RNAi|inhibition of RNA interference|inhibition of posttranscriptional gene silencing by siRNA|negative regulation of RNAi|down-regulation of RNAi|down regulation of posttranscriptional gene silencing by siRNA http://purl.obolibrary.org/obo/GO_1900369 GO:1900368 biolink:BiologicalProcess regulation of RNA interference Any process that modulates the frequency, rate or extent of RNA interference. go-plus.json regulation of posttranscriptional gene silencing by siRNA|regulation of RNAi http://purl.obolibrary.org/obo/GO_1900368 GO:1900363 biolink:BiologicalProcess regulation of mRNA polyadenylation Any process that modulates the frequency, rate or extent of mRNA polyadenylation. go-plus.json regulation of cleavage and polyadenylylation specificity factor activity|regulation of mRNA polyadenylylation http://purl.obolibrary.org/obo/GO_1900363 GO:1900362 biolink:BiologicalProcess positive regulation of pentasaccharide transport Any process that activates or increases the frequency, rate or extent of pentasaccharide transport. go-plus.json up regulation of pentasaccharide transport|activation of pentasaccharide transport|up-regulation of pentasaccharide transport|upregulation of pentasaccharide transport http://purl.obolibrary.org/obo/GO_1900362 GO:1900365 biolink:BiologicalProcess positive regulation of mRNA polyadenylation Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation. go-plus.json up regulation of mRNA polyadenylation|positive regulation of cleavage and polyadenylylation specificity factor activity|up regulation of cleavage and polyadenylylation specificity factor activity|up-regulation of mRNA polyadenylylation|activation of mRNA polyadenylylation|upregulation of mRNA polyadenylation|upregulation of cleavage and polyadenylylation specificity factor activity|positive regulation of mRNA polyadenylylation|activation of mRNA polyadenylation|up regulation of mRNA polyadenylylation|up-regulation of mRNA polyadenylation|up-regulation of cleavage and polyadenylylation specificity factor activity|upregulation of mRNA polyadenylylation|activation of cleavage and polyadenylylation specificity factor activity http://purl.obolibrary.org/obo/GO_1900365 GO:1900364 biolink:BiologicalProcess negative regulation of mRNA polyadenylation Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation. go-plus.json down-regulation of cleavage and polyadenylylation specificity factor activity|negative regulation of cleavage and polyadenylylation specificity factor activity|downregulation of mRNA polyadenylation|down regulation of mRNA polyadenylation|downregulation of cleavage and polyadenylylation specificity factor activity|inhibition of mRNA polyadenylation|down regulation of cleavage and polyadenylylation specificity factor activity|negative regulation of mRNA polyadenylylation|down-regulation of mRNA polyadenylylation|inhibition of cleavage and polyadenylylation specificity factor activity|downregulation of mRNA polyadenylylation|down regulation of mRNA polyadenylylation|down-regulation of mRNA polyadenylation|inhibition of mRNA polyadenylylation http://purl.obolibrary.org/obo/GO_1900364 GO:1900370 biolink:BiologicalProcess positive regulation of RNA interference Any process that activates or increases the frequency, rate or extent of RNA interference. go-plus.json activation of RNAi|up-regulation of RNA interference|upregulation of posttranscriptional gene silencing by siRNA|activation of RNA interference|positive regulation of RNAi|up regulation of RNAi|up regulation of posttranscriptional gene silencing by siRNA|positive regulation of posttranscriptional gene silencing by siRNA|up regulation of RNA interference|upregulation of RNAi|activation of posttranscriptional gene silencing by siRNA|up-regulation of posttranscriptional gene silencing by siRNA|upregulation of RNA interference|up-regulation of RNAi http://purl.obolibrary.org/obo/GO_1900370 GO:1900372 biolink:BiologicalProcess negative regulation of purine nucleotide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes. go-plus.json inhibition of purine nucleotide synthesis|downregulation of purine nucleotide biosynthetic process|down regulation of purine nucleotide anabolism|inhibition of purine nucleotide formation|downregulation of purine nucleotide biosynthesis|downregulation of purine nucleotide anabolism|down regulation of purine nucleotide biosynthesis|down regulation of purine nucleotide synthesis|down regulation of purine nucleotide biosynthetic process|inhibition of purine nucleotide biosynthetic process|down regulation of purine nucleotide formation|downregulation of purine nucleotide synthesis|inhibition of purine nucleotide biosynthesis|downregulation of purine nucleotide formation|negative regulation of purine nucleotide anabolism|down-regulation of purine nucleotide anabolism|negative regulation of purine nucleotide synthesis|down-regulation of purine nucleotide synthesis|negative regulation of purine nucleotide formation|down-regulation of purine nucleotide formation|negative regulation of purine nucleotide biosynthesis|down-regulation of purine nucleotide biosynthesis|down-regulation of purine nucleotide biosynthetic process|inhibition of purine nucleotide anabolism http://purl.obolibrary.org/obo/GO_1900372 GO:1900371 biolink:BiologicalProcess regulation of purine nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes. go-plus.json regulation of purine nucleotide biosynthesis|regulation of purine nucleotide anabolism|regulation of purine nucleotide synthesis|regulation of purine nucleotide formation http://purl.obolibrary.org/obo/GO_1900371 GO:0071479 biolink:BiologicalProcess cellular response to ionizing radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. go-plus.json cellular response to ionising radiation|cellular response to ionizing radiation stimulus http://purl.obolibrary.org/obo/GO_0071479 GO:0071478 biolink:BiologicalProcess cellular response to radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. go-plus.json cellular response to electromagnetic radiation stimulus|cellular response to radiation stimulus http://purl.obolibrary.org/obo/GO_0071478 GO:0071477 biolink:BiologicalProcess cellular hypotonic salinity response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json cellular response to hypotonic salt stress http://purl.obolibrary.org/obo/GO_0071477 GO:0071476 biolink:BiologicalProcess cellular hypotonic response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell. go-plus.json cellular hypo-osmotic response http://purl.obolibrary.org/obo/GO_0071476 GO:0071475 biolink:BiologicalProcess cellular hyperosmotic salinity response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. go-plus.json cellular response to hyperosmotic salt stress http://purl.obolibrary.org/obo/GO_0071475 GO:0071474 biolink:BiologicalProcess cellular hyperosmotic response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. go-plus.json cellular hypertonic response|cellular response to hypertonicity|cellular HOG response http://purl.obolibrary.org/obo/GO_0071474 GO:1900378 biolink:BiologicalProcess positive regulation of secondary metabolite biosynthetic process Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process. go-plus.json up regulation of secondary metabolite biosynthesis|up regulation of secondary metabolite biosynthetic process|activation of secondary metabolite biosynthetic process|positive regulation of secondary metabolite biosynthesis|activation of secondary metabolite biosynthesis|up-regulation of secondary metabolite biosynthetic process|up-regulation of secondary metabolite biosynthesis|upregulation of secondary metabolite biosynthetic process|upregulation of secondary metabolite biosynthesis http://purl.obolibrary.org/obo/GO_1900378 GO:1900377 biolink:BiologicalProcess negative regulation of secondary metabolite biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process. go-plus.json downregulation of secondary metabolite biosynthesis|downregulation of secondary metabolite biosynthetic process|down-regulation of secondary metabolite biosynthetic process|down-regulation of secondary metabolite biosynthesis|negative regulation of secondary metabolite biosynthesis|inhibition of secondary metabolite biosynthetic process|inhibition of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_1900377 GO:1900379 biolink:BiologicalProcess regulation of asperthecin biosynthetic process Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process. go-plus.json regulation of asperthecin synthesis|regulation of asperthecin formation|regulation of asperthecin biosynthesis http://purl.obolibrary.org/obo/GO_1900379 GO:1900374 biolink:BiologicalProcess obsolete positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching. go-plus.json upregulation of mating type switching by regulation of transcription from RNA polymerase II promoter|stimulation of mating type switching by regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by regulation of transcription from RNA polymerase II promoter|activation of mating type switching by regulation of transcription from RNA polymerase II promoter|up regulation of mating type switching by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900374 GO:1900373 biolink:BiologicalProcess positive regulation of purine nucleotide biosynthetic process Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes. go-plus.json up-regulation of purine nucleotide formation|positive regulation of purine nucleotide biosynthesis|up regulation of purine nucleotide biosynthetic process|upregulation of purine nucleotide anabolism|up regulation of purine nucleotide biosynthesis|upregulation of purine nucleotide synthesis|upregulation of purine nucleotide formation|up regulation of purine nucleotide anabolism|upregulation of purine nucleotide biosynthetic process|upregulation of purine nucleotide biosynthesis|positive regulation of purine nucleotide anabolism|up regulation of purine nucleotide synthesis|positive regulation of purine nucleotide synthesis|up regulation of purine nucleotide formation|activation of purine nucleotide anabolism|activation of purine nucleotide biosynthetic process|up-regulation of purine nucleotide biosynthesis|up-regulation of purine nucleotide biosynthetic process|positive regulation of purine nucleotide formation|activation of purine nucleotide synthesis|up-regulation of purine nucleotide anabolism|activation of purine nucleotide formation|activation of purine nucleotide biosynthesis|up-regulation of purine nucleotide synthesis http://purl.obolibrary.org/obo/GO_1900373 GO:1900376 biolink:BiologicalProcess regulation of secondary metabolite biosynthetic process Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process. go-plus.json regulation of secondary metabolite biosynthesis http://purl.obolibrary.org/obo/GO_1900376 GO:1900375 biolink:BiologicalProcess obsolete positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of inositol biosynthetic process. go-plus.json activation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|activation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900375 GO:1900381 biolink:BiologicalProcess positive regulation of asperthecin biosynthetic process Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process. go-plus.json activation of asperthecin formation|up-regulation of asperthecin synthesis|up-regulation of asperthecin biosynthesis|up-regulation of asperthecin biosynthetic process|activation of asperthecin biosynthetic process|up-regulation of asperthecin formation|activation of asperthecin biosynthesis|upregulation of asperthecin synthesis|upregulation of asperthecin formation|positive regulation of asperthecin biosynthesis|up regulation of asperthecin biosynthesis|up regulation of asperthecin biosynthetic process|up regulation of asperthecin synthesis|positive regulation of asperthecin synthesis|up regulation of asperthecin formation|positive regulation of asperthecin formation|upregulation of asperthecin biosynthetic process|upregulation of asperthecin biosynthesis|activation of asperthecin synthesis http://purl.obolibrary.org/obo/GO_1900381 GO:1900380 biolink:BiologicalProcess negative regulation of asperthecin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process. go-plus.json down-regulation of asperthecin formation|negative regulation of asperthecin formation|inhibition of asperthecin biosynthesis|inhibition of asperthecin synthesis|inhibition of asperthecin formation|negative regulation of asperthecin biosynthesis|down-regulation of asperthecin biosynthesis|down-regulation of asperthecin biosynthetic process|down regulation of asperthecin synthesis|down regulation of asperthecin formation|downregulation of asperthecin synthesis|downregulation of asperthecin biosynthetic process|downregulation of asperthecin biosynthesis|downregulation of asperthecin formation|down regulation of asperthecin biosynthetic process|down regulation of asperthecin biosynthesis|inhibition of asperthecin biosynthetic process|down-regulation of asperthecin synthesis|negative regulation of asperthecin synthesis http://purl.obolibrary.org/obo/GO_1900380 GO:1900383 biolink:BiologicalProcess regulation of synaptic plasticity by receptor localization to synapse Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse. go-plus.json regulation of synaptic plasticity by receptor localisation to synapse http://purl.obolibrary.org/obo/GO_1900383 GO:1900382 biolink:BiologicalProcess obsolete regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of thiamine biosynthetic process. go-plus.json regulation of thiamine anabolism by regulation of transcription from RNA polymerase II promoter|regulation of thiamin biosynthetic process by regulation of transcription from RNA polymerase II promoter|regulation of thiamine biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of thiamine formation by regulation of transcription from RNA polymerase II promoter|regulation of thiamine synthesis by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900382 GO:0071495 biolink:BiologicalProcess cellular response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0071495 gocheck_do_not_manually_annotate GO:0071494 biolink:BiologicalProcess cellular response to UV-C Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. go-plus.json cellular response to UV-C radiation stimulus|cellular response to germicidal ultraviolet light stimulus|cellular response to shortwave ultraviolet light stimulus|cellular response to UVC light stimulus|cellular response to germicidal ultraviolet radiation stimulus|cellular response to shortwave ultraviolet radiation stimulus|cellular response to UVC radiation stimulus|cellular response to UV-C light stimulus http://purl.obolibrary.org/obo/GO_0071494 GO:0071493 biolink:BiologicalProcess cellular response to UV-B Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. go-plus.json cellular response to UV-B radiation stimulus|cellular response to medium wave ultraviolet radiation stimulus|cellular response to UVB light stimulus|cellular response to UVB radiation stimulus|cellular response to UV-B light stimulus|cellular response to medium wave ultraviolet light stimulus http://purl.obolibrary.org/obo/GO_0071493 GO:0071492 biolink:BiologicalProcess cellular response to UV-A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. go-plus.json cellular response to UV-A radiation stimulus|cellular response to UVA light stimulus|cellular response to UVA radiation stimulus|cellular response to UV-A light stimulus http://purl.obolibrary.org/obo/GO_0071492 GO:0071491 biolink:BiologicalProcess cellular response to red light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json cellular response to red light stimulus http://purl.obolibrary.org/obo/GO_0071491 GO:0071490 biolink:BiologicalProcess cellular response to far red light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. go-plus.json cellular response to far red light stimulus http://purl.obolibrary.org/obo/GO_0071490 GO:1900389 biolink:BiologicalProcess obsolete regulation of glucose import by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of glucose import. go-plus.json regulation of glucose uptake by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900389 CHEBI:225237 biolink:ChemicalSubstance 2-phenylethanaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_225237 chebi_ph7_3 GO:1900388 biolink:BiologicalProcess obsolete regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of vesicle-mediated transport. go-plus.json regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900388 CHEBI:225238 biolink:ChemicalSubstance benzylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_225238 chebi_ph7_3 GO:1900385 biolink:BiologicalProcess negative regulation of flavonol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process. go-plus.json down-regulation of flavonol biosynthetic process|inhibition of flavonol biosynthetic process|down regulation of flavonol biosynthetic process|downregulation of flavonol biosynthetic process http://purl.obolibrary.org/obo/GO_1900385 GO:1900384 biolink:BiologicalProcess regulation of flavonol biosynthetic process Any process that modulates the frequency, rate or extent of flavonol biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_1900384 GO:1900387 biolink:BiologicalProcess obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_1900387 GO:1900386 biolink:BiologicalProcess positive regulation of flavonol biosynthetic process Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process. go-plus.json up-regulation of flavonol biosynthetic process|upregulation of flavonol biosynthetic process|up regulation of flavonol biosynthetic process|activation of flavonol biosynthetic process http://purl.obolibrary.org/obo/GO_1900386 GO:1900392 biolink:BiologicalProcess obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900392 GO:1900391 biolink:BiologicalProcess obsolete regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cAMP-mediated signaling. go-plus.json regulation of cAMP-mediated signalling by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900391 GO:1900394 biolink:BiologicalProcess regulation of kojic acid biosynthetic process Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process. go-plus.json regulation of C6H6O4 formation|regulation of kojic acid synthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|regulation of kojic acid formation|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|regulation of kojic acid biosynthesis|regulation of C6H6O4 biosynthetic process|regulation of C6H6O4 biosynthesis|regulation of C6H6O4 anabolism|regulation of C6H6O4 synthesis|regulation of kojic acid anabolism http://purl.obolibrary.org/obo/GO_1900394 GO:1900393 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900393 GO:1900390 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900390 GO:0071499 biolink:BiologicalProcess cellular response to laminar fluid shear stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. go-plus.json http://purl.obolibrary.org/obo/GO_0071499 GO:0071498 biolink:BiologicalProcess cellular response to fluid shear stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. go-plus.json http://purl.obolibrary.org/obo/GO_0071498 GO:0071497 biolink:BiologicalProcess cellular response to freezing Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius. go-plus.json ice nucleation inhibitor activity|antifreeze activity http://purl.obolibrary.org/obo/GO_0071497 GO:0071496 biolink:BiologicalProcess cellular response to external stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071496 gocheck_do_not_manually_annotate CHEBI:142493 biolink:ChemicalSubstance (3S,4R,5R,6S)-1,3,4,5,6-pentachlorocyclohexene go-plus.json http://purl.obolibrary.org/obo/CHEBI_142493 chebi_ph7_3 GO:1900399 biolink:BiologicalProcess positive regulation of pyrimidine nucleotide biosynthetic process Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process. go-plus.json up-regulation of pyrimidine nucleotide synthesis|up-regulation of pyrimidine nucleotide formation|upregulation of pyrimidine nucleotide biosynthetic process|upregulation of pyrimidine nucleotide biosynthesis|upregulation of pyrimidine nucleotide anabolism|upregulation of pyrimidine nucleotide synthesis|upregulation of pyrimidine nucleotide formation|up-regulation of pyrimidine nucleotide biosynthetic process|activation of pyrimidine nucleotide biosynthetic process|up-regulation of pyrimidine nucleotide biosynthesis|up regulation of pyrimidine nucleotide anabolism|positive regulation of pyrimidine nucleotide anabolism|up regulation of pyrimidine nucleotide synthesis|activation of pyrimidine nucleotide biosynthesis|positive regulation of pyrimidine nucleotide synthesis|up regulation of pyrimidine nucleotide formation|activation of pyrimidine nucleotide anabolism|positive regulation of pyrimidine nucleotide formation|positive regulation of pyrimidine nucleotide biosynthesis|activation of pyrimidine nucleotide synthesis|up regulation of pyrimidine nucleotide biosynthesis|up regulation of pyrimidine nucleotide biosynthetic process|up-regulation of pyrimidine nucleotide anabolism|activation of pyrimidine nucleotide formation http://purl.obolibrary.org/obo/GO_1900399 GO:1900396 biolink:BiologicalProcess positive regulation of kojic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process. go-plus.json up regulation of kojic acid formation|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|upregulation of C6H6O4 synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of kojic acid anabolism|activation of C6H6O4 biosynthetic process|activation of C6H6O4 biosynthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of kojic acid biosynthesis|upregulation of kojic acid biosynthetic process|upregulation of C6H6O4 formation|upregulation of kojic acid synthesis|up-regulation of C6H6O4 anabolism|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|up-regulation of C6H6O4 biosynthetic process|up-regulation of C6H6O4 biosynthesis|upregulation of kojic acid formation|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up-regulation of kojic acid anabolism|up-regulation of C6H6O4 synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of C6H6O4 anabolism|up regulation of kojic acid biosynthetic process|up-regulation of C6H6O4 formation|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up regulation of kojic acid biosynthesis|up-regulation of kojic acid synthesis|positive regulation of kojic acid biosynthesis|activation of kojic acid biosynthetic process|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of kojic acid anabolism|activation of C6H6O4 synthesis|up-regulation of kojic acid formation|positive regulation of C6H6O4 anabolism|upregulation of C6H6O4 biosynthesis|upregulation of C6H6O4 biosynthetic process|up regulation of C6H6O4 anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|activation of C6H6O4 formation|activation of kojic acid biosynthesis|activation of kojic acid synthesis|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|positive regulation of kojic acid anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|positive regulation of C6H6O4 synthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up regulation of C6H6O4 synthesis|up regulation of kojic acid anabolism|activation of kojic acid formation|positive regulation of C6H6O4 formation|positive regulation of kojic acid synthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|up regulation of C6H6O4 formation|up-regulation of kojic acid biosynthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of kojic acid biosynthetic process|up regulation of C6H6O4 biosynthesis|up regulation of kojic acid synthesis|up regulation of C6H6O4 biosynthetic process|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|positive regulation of kojic acid formation|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of C6H6O4 anabolism|positive regulation of C6H6O4 biosynthesis|positive regulation of C6H6O4 biosynthetic process http://purl.obolibrary.org/obo/GO_1900396 GO:1900395 biolink:BiologicalProcess negative regulation of kojic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process. go-plus.json downregulation of kojic acid synthesis|down regulation of kojic acid anabolism|down regulation of C6H6O4 synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|inhibition of kojic acid biosynthesis|inhibition of C6H6O4 anabolism|down-regulation of C6H6O4 biosynthesis|down-regulation of C6H6O4 biosynthetic process|negative regulation of C6H6O4 biosynthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|downregulation of kojic acid formation|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down regulation of C6H6O4 formation|negative regulation of C6H6O4 biosynthetic process|down regulation of kojic acid synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|inhibition of C6H6O4 synthesis|inhibition of kojic acid anabolism|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down regulation of kojic acid formation|down regulation of kojic acid biosynthetic process|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|down regulation of kojic acid biosynthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|inhibition of C6H6O4 formation|inhibition of kojic acid synthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of kojic acid biosynthetic process|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|downregulation of kojic acid biosynthesis|inhibition of kojic acid formation|inhibition of C6H6O4 biosynthetic process|down-regulation of C6H6O4 anabolism|inhibition of C6H6O4 biosynthesis|negative regulation of C6H6O4 anabolism|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down-regulation of C6H6O4 synthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|negative regulation of C6H6O4 synthesis|negative regulation of kojic acid anabolism|down-regulation of kojic acid anabolism|down-regulation of kojic acid biosynthetic process|down-regulation of kojic acid biosynthesis|negative regulation of kojic acid biosynthesis|down-regulation of C6H6O4 formation|down regulation of C6H6O4 biosynthesis|negative regulation of C6H6O4 formation|down regulation of C6H6O4 biosynthetic process|down-regulation of kojic acid synthesis|negative regulation of kojic acid synthesis|downregulation of C6H6O4 anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of C6H6O4 biosynthetic process|downregulation of C6H6O4 biosynthesis|negative regulation of kojic acid formation|down-regulation of kojic acid formation|inhibition of kojic acid biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|downregulation of kojic acid anabolism|downregulation of C6H6O4 synthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of C6H6O4 anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|downregulation of C6H6O4 formation|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation http://purl.obolibrary.org/obo/GO_1900395 GO:1900398 biolink:BiologicalProcess negative regulation of pyrimidine nucleotide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process. go-plus.json inhibition of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide biosynthesis|down regulation of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide synthesis|down regulation of pyrimidine nucleotide anabolism|inhibition of pyrimidine nucleotide formation|inhibition of pyrimidine nucleotide biosynthesis|down regulation of pyrimidine nucleotide synthesis|downregulation of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide formation|downregulation of pyrimidine nucleotide synthesis|downregulation of pyrimidine nucleotide formation|down-regulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide biosynthetic process|down-regulation of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide synthesis|negative regulation of pyrimidine nucleotide synthesis|down-regulation of pyrimidine nucleotide formation|negative regulation of pyrimidine nucleotide formation|downregulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900398 GO:1900397 biolink:BiologicalProcess regulation of pyrimidine nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process. go-plus.json regulation of pyrimidine nucleotide biosynthesis|regulation of pyrimidine nucleotide anabolism|regulation of pyrimidine nucleotide synthesis|regulation of pyrimidine nucleotide formation http://purl.obolibrary.org/obo/GO_1900397 OIO:SynonymTypeProperty biolink:OntologyClass synonym_type_property go-plus.json http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty CHEBI:59087 biolink:ChemicalSubstance N-{alpha-Man-(1->3)-[alpha-Man-(1->3)-[alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNac}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_59087 chebi_ph7_3 CHEBI:59082 biolink:ChemicalSubstance N-{alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_59082 chebi_ph7_3 CHEBI:59080 biolink:ChemicalSubstance N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_59080 chebi_ph7_3 GO:0046440 biolink:BiologicalProcess L-lysine metabolic process The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid. go-plus.json L-lysine metabolism http://purl.obolibrary.org/obo/GO_0046440 CHEBI:60061 biolink:ChemicalSubstance cobalt-precorrin-4(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60061 chebi_ph7_3 GO:0046448 biolink:BiologicalProcess tropane alkaloid metabolic process The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system. go-plus.json tropane alkaloid metabolism http://purl.obolibrary.org/obo/GO_0046448 CHEBI:60060 biolink:ChemicalSubstance cobalt-precorrin-3(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60060 chebi_ph7_3 GO:0046447 biolink:BiologicalProcess terpenoid indole alkaloid metabolic process The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate). go-plus.json terpenoid indole alkaloid metabolism http://purl.obolibrary.org/obo/GO_0046447 GO:0046446 biolink:BiologicalProcess purine alkaloid metabolic process The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure. go-plus.json purine alkaloid metabolism http://purl.obolibrary.org/obo/GO_0046446 CHEBI:60063 biolink:ChemicalSubstance cobalt-precorrin-5B(8-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60063 chebi_ph7_3 GO:0046445 biolink:BiologicalProcess benzyl isoquinoline alkaloid metabolic process The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings. go-plus.json benzyl isoquinoline alkaloid metabolism http://purl.obolibrary.org/obo/GO_0046445 CHEBI:60062 biolink:ChemicalSubstance cobalt-precorrin-5A(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60062 chebi_ph7_3 GO:0046444 biolink:BiologicalProcess FMN metabolic process The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase. go-plus.json FMN metabolism http://purl.obolibrary.org/obo/GO_0046444 CHEBI:84029 biolink:ChemicalSubstance (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84029 chebi_ph7_3 CHEBI:60065 biolink:ChemicalSubstance alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60065 chebi_ph7_3 CHEBI:84028 biolink:ChemicalSubstance 12,13-DiHOME(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84028 chebi_ph7_3 GO:0046443 biolink:BiologicalProcess FAD metabolic process The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide. go-plus.json oxidized flavin adenine dinucleotide metabolic process|oxidized flavin adenine dinucleotide metabolism|oxidized flavin-adenine dinucleotide metabolism|oxidized flavin-adenine dinucleotide metabolic process|FAD metabolism http://purl.obolibrary.org/obo/GO_0046443 CHEBI:60064 biolink:ChemicalSubstance cobalt-precorrin-6A(7-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60064 chebi_ph7_3 CHEBI:84027 biolink:ChemicalSubstance 9,10-DiHOME(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84027 chebi_ph7_3 GO:0046442 biolink:BiologicalProcess aerobactin metabolic process The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid. go-plus.json aerobactin metabolism http://purl.obolibrary.org/obo/GO_0046442 CHEBI:84026 biolink:ChemicalSubstance vernolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84026 chebi_ph7_3 GO:0046441 biolink:BiologicalProcess D-lysine metabolic process The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid. go-plus.json D-lysine metabolism http://purl.obolibrary.org/obo/GO_0046441 CHEBI:84025 biolink:ChemicalSubstance 8,9-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84025 chebi_ph7_3 CHEBI:84024 biolink:ChemicalSubstance 14,15-EET(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84024 chebi_ph7_3 CL:0002022 biolink:Cell Ly-76 high positive erythrocyte An enucleate erythrocyte that is Lyg-76-high. go-plus.json http://purl.obolibrary.org/obo/CL_0002022 CHEBI:84023 biolink:ChemicalSubstance 9(10)-EpOME(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84023 chebi_ph7_3 GO:0071409 biolink:BiologicalProcess cellular response to cycloheximide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes. go-plus.json cellular response to actidione http://purl.obolibrary.org/obo/GO_0071409 CL:0002024 biolink:Cell Kit-positive megakaryocyte progenitor cell A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low. go-plus.json http://purl.obolibrary.org/obo/CL_0002024 GO:0071408 biolink:BiologicalProcess cellular response to cycloalkane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n. go-plus.json http://purl.obolibrary.org/obo/GO_0071408 CL:0002027 biolink:Cell CD9-positive, CD41-positive megakaryocyte cell A megakaryocyte cell with is CD9-positive and CD41-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002027 GO:0071407 biolink:BiologicalProcess cellular response to organic cyclic compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. go-plus.json cellular response to organic cyclic substance http://purl.obolibrary.org/obo/GO_0071407 GO:0071406 biolink:BiologicalProcess cellular response to methylmercury Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus. go-plus.json cellular response to MeHg+|cellular response to CH3-Hg+ http://purl.obolibrary.org/obo/GO_0071406 CL:0002029 biolink:Cell Fc-epsilon RIalpha-low mast cell progenitor A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low. go-plus.json http://purl.obolibrary.org/obo/CL_0002029 CL:0002028 biolink:Cell basophil mast progenitor cell A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa go-plus.json BMCP http://purl.obolibrary.org/obo/CL_0002028 GO:0071405 biolink:BiologicalProcess cellular response to methanol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071405 GO:0046449 biolink:BiologicalProcess creatinine metabolic process The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine. go-plus.json creatinine metabolism http://purl.obolibrary.org/obo/GO_0046449 GO:0071404 biolink:BiologicalProcess cellular response to low-density lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus. go-plus.json response to low density lipoprotein particle|response to low-density lipoprotein particle stimulus|response to low-density lipoprotein particle http://purl.obolibrary.org/obo/GO_0071404 GO:0071403 biolink:BiologicalProcess cellular response to high density lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus. go-plus.json response to high density lipoprotein particle stimulus|response to high density lipoprotein particle|cellular response to high-density lipoprotein particle stimulus http://purl.obolibrary.org/obo/GO_0071403 GO:0071402 biolink:BiologicalProcess cellular response to lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071402 CHEBI:49709 biolink:ChemicalSubstance chlorate go-plus.json http://purl.obolibrary.org/obo/CHEBI_49709 chebi_ph7_3 GO:0071401 biolink:BiologicalProcess cellular response to triglyceride Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus. go-plus.json cellular response to triacylglyceride|cellular response to triacylglycerol http://purl.obolibrary.org/obo/GO_0071401 GO:0071400 biolink:BiologicalProcess cellular response to oleic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus. go-plus.json cellular response to oleate http://purl.obolibrary.org/obo/GO_0071400 CL:0002021 biolink:Cell GlyA-positive erythrocyte An enucleate erythrocyte that is GlyA-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002021 CL:0002020 biolink:Cell GlyA-positive reticulocytes A reticulocyte that is GlyA-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002020 GO:0046451 biolink:BiologicalProcess diaminopimelate metabolic process The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls. go-plus.json diaminopimelate metabolism http://purl.obolibrary.org/obo/GO_0046451 GO:0046450 biolink:BiologicalProcess dethiobiotin metabolic process The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms. go-plus.json desthiobiotin metabolic process|dethiobiotin metabolism|desthiobiotin metabolism http://purl.obolibrary.org/obo/GO_0046450 CHEBI:25741 biolink:ChemicalSubstance oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25741 CHEBI:25747 biolink:ChemicalSubstance oxidized luciferins go-plus.json http://purl.obolibrary.org/obo/CHEBI_25747 GO:0046459 biolink:BiologicalProcess short-chain fatty acid metabolic process The chemical reactions and pathways involving fatty acids with a chain length of less than C6. go-plus.json short-chain fatty acid metabolism http://purl.obolibrary.org/obo/GO_0046459 GO:0046458 biolink:BiologicalProcess hexadecanal metabolic process The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde. go-plus.json hexadecanal metabolism http://purl.obolibrary.org/obo/GO_0046458 GO:0046457 biolink:BiologicalProcess prostanoid biosynthetic process The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure. Wikipedia:Prostanoid#Biosynthesis go-plus.json prostanoid anabolism|prostanoid synthesis|prostanoid formation|prostanoid biosynthesis http://purl.obolibrary.org/obo/GO_0046457 GO:0046456 biolink:BiologicalProcess icosanoid biosynthetic process The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. Wikipedia:Eicosanoid go-plus.json eoxin synthesis|eoxin biosynthesis|icosanoid anabolism|icosanoid synthesis|eicosanoid biosynthetic process|eicosanoid biosynthesis|icosanoid formation|icosanoid biosynthesis http://purl.obolibrary.org/obo/GO_0046456 CHEBI:60073 biolink:ChemicalSubstance N-acylneuraminate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60073 chebi_ph7_3 GO:0046455 biolink:BiologicalProcess organosilicon catabolic process The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon. go-plus.json organosilicon catabolism|organosilicone catabolism|organosilicon degradation|organosilicon breakdown|organosilicone catabolic process http://purl.obolibrary.org/obo/GO_0046455 CHEBI:60076 biolink:ChemicalSubstance 6-O-sinapoyl-D-glucono-1,5-lactone go-plus.json http://purl.obolibrary.org/obo/CHEBI_60076 chebi_ph7_3 GO:0046454 biolink:BiologicalProcess dimethylsilanediol metabolic process The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products. go-plus.json dimethylsilanediol metabolism http://purl.obolibrary.org/obo/GO_0046454 CHEBI:60078 biolink:ChemicalSubstance 4-O-feruloyl-D-quinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60078 chebi_ph7_3 GO:0046453 biolink:BiologicalProcess dipyrrin metabolic process The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group. go-plus.json dipyrrin metabolism http://purl.obolibrary.org/obo/GO_0046453 CHEBI:60077 biolink:ChemicalSubstance luteolin-7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] go-plus.json http://purl.obolibrary.org/obo/CHEBI_60077 GO:0046452 biolink:BiologicalProcess dihydrofolate metabolic process The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate. go-plus.json dihydrofolate reduction|dihydrofolate metabolism http://purl.obolibrary.org/obo/GO_0046452 CL:0002034 biolink:Cell long term hematopoietic stem cell A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. go-plus.json LT-HSC|LT stem cell http://purl.obolibrary.org/obo/CL_0002034 CL:0002033 biolink:Cell short term hematopoietic stem cell A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. go-plus.json ST stem cell|ST-HSC http://purl.obolibrary.org/obo/CL_0002033 CHEBI:60079 biolink:ChemicalSubstance alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60079 chebi_ph7_3 CL:0002036 biolink:Cell Slamf1-positive multipotent progenitor cell A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive. go-plus.json KSL cell http://purl.obolibrary.org/obo/CL_0002036 CL:0002035 biolink:Cell Slamf1-negative multipotent progenitor cell A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002035 CL:0002038 biolink:Cell T follicular helper cell A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. go-plus.json follicular T cell|Tfh|T(FH)|follicular helper T-cell|follicular T-cell|follicular B helper T cell|follicular helper T cell|follicular T-helper cell http://purl.obolibrary.org/obo/CL_0002038 CHEBI:84032 biolink:ChemicalSubstance (5Z,11Z,14Z)-8,9-dihydroxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84032 chebi_ph7_3 CL:0002037 biolink:Cell CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive. go-plus.json memory alpha beta IEL http://purl.obolibrary.org/obo/CL_0002037 CHEBI:84031 biolink:ChemicalSubstance (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84031 chebi_ph7_3 CL:0002039 biolink:Cell immature NK T cell stage I A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell. go-plus.json http://purl.obolibrary.org/obo/CL_0002039 NCBITaxon:71527 biolink:OrganismalEntity Tenebrionoidea go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_71527 CL:0002030 biolink:Cell Fc-epsilon RIalpha-high basophil progenitor cell A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high. go-plus.json http://purl.obolibrary.org/obo/CL_0002030 UBERON:0002597 biolink:AnatomicalEntity principal sensory nucleus of trigeminal nerve The principal sensory nucleus (or chief sensory nucleus of V) is a group of second order neurons which have cell bodies in the dorsal Pons. It receives information about discriminative sensation and light touch of the face as well as conscious proprioception of the jaw via first order neurons of CN V. Most of the sensory information crosses the midline and travels to the contralateral ventral posteriomedial (VPM) of the thalamus via the Ventral Trigeminothalamic Tract, but information of the oral cavity travels to the ipsilateral Ventral Posteriomedial (VPM) of the thalamus via the Dorsal Trigeminothalamic Tract. [WP,unvetted]. go-plus.json principal sensory nucleus of the trigeminal nerve|nucleus sensibilis superior nervi trigemini|main sensory nucleus|trigeminal V principal sensory nucleus|pontine nucleus|principal sensory nucleus of trigeminal nerve|principal sensory nucleus of the trigeminal|primary nucleus of the trigeminal nerve|trigeminal nerve superior sensory nucleus|main sensory nucleus of cranial nerve v|nucleus sensorius principalis nervi trigemini|trigeminal V chief sensory nucleus|principal sensory nucleus|pontine nucleus of the trigeminal nerve|nucleus pontinus nervi trigemini|chief sensory trigeminal nucleus|chief trigeminal sensory nucleus|nucleus sensorius superior nervi trigemini|principal sensory trigeminal nucleus|principal trigeminal nucleus|chief sensory nucleus|nucleus pontinus nervi trigeminalis|superior trigeminal nucleus|superior trigeminal sensory nucleus|nucleus principalis nervi trigemini http://purl.obolibrary.org/obo/UBERON_0002597 CL:0002032 biolink:Cell hematopoietic oligopotent progenitor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. go-plus.json http://purl.obolibrary.org/obo/CL_0002032 CL:0002031 biolink:Cell hematopoietic lineage restricted progenitor cell A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. go-plus.json http://purl.obolibrary.org/obo/CL_0002031 GO:0046462 biolink:BiologicalProcess monoacylglycerol metabolic process The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. go-plus.json monoacylglycerol metabolism|monoglyceride metabolic process|monoglyceride metabolism http://purl.obolibrary.org/obo/GO_0046462 CHEBI:25710 biolink:ChemicalSubstance organophosphorus compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25710 GO:0046461 biolink:BiologicalProcess neutral lipid catabolic process The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity. go-plus.json neutral lipid breakdown|neutral lipid degradation|neutral lipid catabolism http://purl.obolibrary.org/obo/GO_0046461 GO:0046460 biolink:BiologicalProcess neutral lipid biosynthetic process The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity. go-plus.json neutral lipid biosynthesis|neutral lipid anabolism|neutral lipid synthesis|neutral lipid formation http://purl.obolibrary.org/obo/GO_0046460 CHEBI:25713 biolink:ChemicalSubstance organosilicon compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25713 CHEBI:60081 biolink:ChemicalSubstance viomycin(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60081 chebi_ph7_3 CHEBI:25712 biolink:ChemicalSubstance organoselenium compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25712 CHEBI:25711 biolink:ChemicalSubstance organophosphorus insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25711 CHEBI:60080 biolink:ChemicalSubstance O-phosphoviomycin(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60080 chebi_ph7_3 CHEBI:60083 biolink:ChemicalSubstance galactitol 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60083 chebi_ph7_3 CL:0002009 biolink:Cell macrophage dendritic cell progenitor A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. go-plus.json MDP http://purl.obolibrary.org/obo/CL_0002009 GO:0046469 biolink:BiologicalProcess platelet activating factor metabolic process The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli. go-plus.json PAF metabolic process|PAF metabolism|platelet activating factor metabolism http://purl.obolibrary.org/obo/GO_0046469 CHEBI:60082 biolink:ChemicalSubstance vinca alkaloid cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60082 CL:0002008 biolink:Cell CD34-positive, CD38-positive eosinophil progenitor cell A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell. go-plus.json http://purl.obolibrary.org/obo/CL_0002008 GO:0046468 biolink:BiologicalProcess phosphatidyl-N-monomethylethanolamine metabolic process The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria. go-plus.json PMME metabolic process|PMME metabolism|phosphatidyl-N-monomethylethanolamine metabolism http://purl.obolibrary.org/obo/GO_0046468 CHEBI:60085 biolink:ChemicalSubstance phosphoethanolamine-Kdo2-lipid A(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60085 chebi_ph7_3 GO:0046467 biolink:BiologicalProcess membrane lipid biosynthetic process The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. go-plus.json membrane lipid anabolism|membrane lipid synthesis|membrane lipid formation|membrane lipid biosynthesis http://purl.obolibrary.org/obo/GO_0046467 CHEBI:60084 biolink:ChemicalSubstance D-glucitol 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60084 chebi_ph7_3 GO:0046466 biolink:BiologicalProcess membrane lipid catabolic process The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane. go-plus.json membrane lipid catabolism|membrane lipid peroxidation|membrane lipid degradation|membrane lipid breakdown http://purl.obolibrary.org/obo/GO_0046466 CHEBI:60087 biolink:ChemicalSubstance 3-(cis-5,6-dihydroxycyclohexa-1,3-dienyl)propanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60087 chebi_ph7_3 GO:0046465 biolink:BiologicalProcess dolichyl diphosphate metabolic process The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes. go-plus.json dolichyl diphosphate metabolism http://purl.obolibrary.org/obo/GO_0046465 CHEBI:60086 biolink:ChemicalSubstance lipid A oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60086 GO:0046464 biolink:BiologicalProcess acylglycerol catabolic process The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. go-plus.json acylglycerol degradation|acylglycerol breakdown|acylglycerol catabolism http://purl.obolibrary.org/obo/GO_0046464 GO:0046463 biolink:BiologicalProcess acylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. go-plus.json acylglycerol anabolism|acylglycerol synthesis|acylglycerol formation|acylglycerol biosynthesis http://purl.obolibrary.org/obo/GO_0046463 CL:0002001 biolink:Cell CD34-positive, CD38-positive granulocyte monocyte progenitor A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002001 CL:0002000 biolink:Cell Kit-positive erythroid progenitor cell An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative. go-plus.json c- Kit-positive erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0002000 CHEBI:84046 biolink:ChemicalSubstance pyoverdine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84046 CL:0002003 biolink:Cell CD34-positive, GlyA-negative erythroid progenitor cell An erythroid progenitor cell that is CD34-positive and is GlyA-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002003 CL:0002002 biolink:Cell Kit-positive granulocyte monocyte progenitor A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002002 CL:0002005 biolink:Cell CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002005 GO:0071429 biolink:BiologicalProcess snRNA-containing ribonucleoprotein complex export from nucleus The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm. go-plus.json snRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|snRNA-containing ribonucleoprotein complex nucleus export|snRNA-containing ribonucleoprotein complex export from cell nucleus|snRNA-containing RNP export from nucleus http://purl.obolibrary.org/obo/GO_0071429 CL:0002004 biolink:Cell CD34-negative, GlyA-negative proerythroblast A proerythoblast that is CD34-negative and GlyA-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002004 CHEBI:84042 biolink:ChemicalSubstance 2,3-dipalmitoyl-alpha,alpha-trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_84042 chebi_ph7_3 GO:0071428 biolink:BiologicalProcess rRNA-containing ribonucleoprotein complex export from nucleus The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm. go-plus.json rRNA-containing RNP export from nucleus|rRNA-containing ribonucleoprotein complex nucleus export|rRNA-containing ribonucleoprotein complex export from cell nucleus|rRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0071428 CL:0002007 biolink:Cell Kit-low, CD34-positive eosinophil progenitor cell A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell. go-plus.json http://purl.obolibrary.org/obo/CL_0002007 CHEBI:84041 biolink:ChemicalSubstance 2-O-palmitoyl-alpha,alpha-trehalose go-plus.json http://purl.obolibrary.org/obo/CHEBI_84041 chebi_ph7_3 GO:0071427 biolink:BiologicalProcess mRNA-containing ribonucleoprotein complex export from nucleus The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm. go-plus.json mRNA-containing ribonucleoprotein complex nucleus export|mRNA-containing ribonucleoprotein complex export from cell nucleus|mRNA-containing RNP export from nucleus|mRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0071427 CL:0002006 biolink:Cell Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low. go-plus.json http://purl.obolibrary.org/obo/CL_0002006 GO:0071426 biolink:BiologicalProcess ribonucleoprotein complex export from nucleus The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm. go-plus.json ribonucleoprotein complex transport from nucleus to cytoplasm|ribonucleoprotein complex export from cell nucleus|RNP export from nucleus|ribonucleoprotein complex nucleus export http://purl.obolibrary.org/obo/GO_0071426 CHEBI:25718 biolink:ChemicalSubstance ornithine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_25718 GO:0071425 biolink:BiologicalProcess hematopoietic stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. go-plus.json hemopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0071425 CHEBI:25717 biolink:ChemicalSubstance organotin compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25717 GO:0071424 biolink:MolecularActivity rRNA (cytosine-N4-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0071424 CHEBI:25716 biolink:ChemicalSubstance organothiophosphorus compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25716 GO:0071423 biolink:BiologicalProcess malate transmembrane transport A process in which a malate ion is transported across a membrane. go-plus.json transmembrane malate transport|malate membrane transport http://purl.obolibrary.org/obo/GO_0071423 CHEBI:25715 biolink:ChemicalSubstance organothiophosphate insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25715 GO:0071422 biolink:BiologicalProcess succinate transmembrane transport The process in which succinate is transported across a membrane. go-plus.json succinate membrane transport|transmembrane succinate transport http://purl.obolibrary.org/obo/GO_0071422 UBERON:0002583 biolink:AnatomicalEntity commissure of superior colliculus A commissure that is part of a superior colliculus [Automatically generated definition]. go-plus.json commissura colliculi superioris|commissure of the superior colliculus|intertectal commissure|commissure of optic tectum|superior colliculus commissure|optic tectum commissure|commissure of the superior colliculi|commissura colliculi superior|commissure of cranial colliculus|commissura colliculorum superiorum|commissura colliculorum cranialium|commissure of superior colliculi|commissure of anterior colliculus|anterior corpus quadrigeminum commissure|commissura colliculorum rostralium|commissure of anterior corpus quadrigeminum|cranial colliculus commissure|anterior colliculus commissure http://purl.obolibrary.org/obo/UBERON_0002583 GO:0071421 biolink:BiologicalProcess manganese ion transmembrane transport A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json transmembrane manganese transport|manganese ion membrane transport http://purl.obolibrary.org/obo/GO_0071421 GO:0071420 biolink:BiologicalProcess cellular response to histamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. go-plus.json cellular response to histamine stimulus http://purl.obolibrary.org/obo/GO_0071420 GO:1900309 biolink:BiologicalProcess regulation of maltoheptaose metabolic process Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process. go-plus.json regulation of maltoheptaose metabolism http://purl.obolibrary.org/obo/GO_1900309 GO:0046473 biolink:BiologicalProcess phosphatidic acid metabolic process The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. go-plus.json phosphatidic acid metabolism http://purl.obolibrary.org/obo/GO_0046473 GO:0046472 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046472 GO:1900308 biolink:BiologicalProcess positive regulation of maltoheptaose transport Any process that activates or increases the frequency, rate or extent of maltoheptaose transport. go-plus.json up regulation of maltoheptaose transport|activation of maltoheptaose transport|up-regulation of maltoheptaose transport|upregulation of maltoheptaose transport http://purl.obolibrary.org/obo/GO_1900308 GO:0046471 biolink:BiologicalProcess phosphatidylglycerol metabolic process The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes. go-plus.json phosphatidylglycerol metabolism http://purl.obolibrary.org/obo/GO_0046471 GO:0046470 biolink:BiologicalProcess phosphatidylcholine metabolic process The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes. go-plus.json phosphatidylcholine metabolism http://purl.obolibrary.org/obo/GO_0046470 CHEBI:60090 biolink:ChemicalSubstance 7-hydroxyflavon-3-olate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60090 chebi_ph7_3 GO:1900305 biolink:BiologicalProcess positive regulation of laminaritriose transport Any process that activates or increases the frequency, rate or extent of laminaritriose transport. go-plus.json up-regulation of laminaritriose transport|activation of laminaritriose transport|up regulation of laminaritriose transport|upregulation of laminaritriose transport http://purl.obolibrary.org/obo/GO_1900305 GO:1900304 biolink:BiologicalProcess negative regulation of laminaritriose transport Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport. go-plus.json down-regulation of laminaritriose transport|downregulation of laminaritriose transport|down regulation of laminaritriose transport|inhibition of laminaritriose transport http://purl.obolibrary.org/obo/GO_1900304 CHEBI:60092 biolink:ChemicalSubstance SL659 go-plus.json http://purl.obolibrary.org/obo/CHEBI_60092 chebi_ph7_3 GO:1900307 biolink:BiologicalProcess negative regulation of maltoheptaose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport. go-plus.json downregulation of maltoheptaose transport|down-regulation of maltoheptaose transport|inhibition of maltoheptaose transport|down regulation of maltoheptaose transport http://purl.obolibrary.org/obo/GO_1900307 CHEBI:60091 biolink:ChemicalSubstance alpha,alpha-trehalose-2-sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60091 chebi_ph7_3 GO:1900306 biolink:BiologicalProcess regulation of maltoheptaose transport Any process that modulates the frequency, rate or extent of maltoheptaose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900306 GO:1900301 biolink:BiologicalProcess negative regulation of laminarabiose transport Any process that stops, prevents or reduces the frequency, rate or extent of laminarabiose transport. go-plus.json down regulation of laminarabiose transport|downregulation of laminarabiose transport|down-regulation of laminarabiose transport|inhibition of laminarabiose transport http://purl.obolibrary.org/obo/GO_1900301 GO:1900300 biolink:BiologicalProcess regulation of laminarabiose transport Any process that modulates the frequency, rate or extent of laminarabiose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900300 CL:0002019 biolink:Cell Ly-76 high reticulocyte A reticulocyte that is Ly76-high and is Kit-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002019 GO:0046479 biolink:BiologicalProcess glycosphingolipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. go-plus.json glycosphingolipid degradation|glycosphingolipid catabolism|glycosphingolipid breakdown http://purl.obolibrary.org/obo/GO_0046479 GO:1900303 biolink:BiologicalProcess regulation of laminaritriose transport Any process that modulates the frequency, rate or extent of laminaritriose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900303 CHEBI:60096 biolink:ChemicalSubstance poly(glycerol phosphate) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60096 GO:1900302 biolink:BiologicalProcess positive regulation of laminarabiose transport Any process that activates or increases the frequency, rate or extent of laminarabiose transport. go-plus.json upregulation of laminarabiose transport|up regulation of laminarabiose transport|activation of laminarabiose transport|up-regulation of laminarabiose transport http://purl.obolibrary.org/obo/GO_1900302 GO:0046478 biolink:BiologicalProcess lactosylceramide metabolic process The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. go-plus.json lactosylceramide metabolism http://purl.obolibrary.org/obo/GO_0046478 GO:0046477 biolink:BiologicalProcess glycosylceramide catabolic process The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. go-plus.json glycosylceramide catabolism|glycosylceramide degradation|glycosylceramide breakdown http://purl.obolibrary.org/obo/GO_0046477 GO:0046476 biolink:BiologicalProcess glycosylceramide biosynthetic process The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. go-plus.json glycosylceramide synthesis|glycosylceramide formation|glycosylceramide biosynthesis|glycosylceramide anabolism http://purl.obolibrary.org/obo/GO_0046476 GO:0046475 biolink:BiologicalProcess glycerophospholipid catabolic process The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. go-plus.json glycerophospholipid breakdown|phosphoglyceride catabolism|phosphoglyceride catabolic process|glycerophospholipid degradation|glycerophospholipid catabolism http://purl.obolibrary.org/obo/GO_0046475 CHEBI:84059 biolink:ChemicalSubstance octyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84059 chebi_ph7_3 GO:0046474 biolink:BiologicalProcess glycerophospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. go-plus.json glycerophospholipid biosynthesis|glycerophospholipid anabolism|glycerophospholipid synthesis|phosphoglyceride biosynthesis|phosphoglyceride biosynthetic process|glycerophospholipid formation http://purl.obolibrary.org/obo/GO_0046474 CL:0002012 biolink:Cell Kit-low proerythroblast A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002012 CL:0002011 biolink:Cell Kit-positive macrophage dendritic cell progenitor A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative. go-plus.json murine MDP http://purl.obolibrary.org/obo/CL_0002011 CL:0002014 biolink:Cell Kit-negative, Ly-76 high basophilic erythroblast A basophilic erythroblast that is Lyg 76-high and is Kit-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002014 CHEBI:84055 biolink:ChemicalSubstance pentose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84055 CL:0002013 biolink:Cell GlyA-positive basophillic erythroblast A basophilic erythroblast that is GlyA-positive. go-plus.json http://purl.obolibrary.org/obo/CL_0002013 CL:0002016 biolink:Cell CD71-low, GlyA-positive polychromatic erythroblast A polychromatiic erythroblast that is Gly-A-positive and CD71-low. go-plus.json http://purl.obolibrary.org/obo/CL_0002016 GO:0071419 biolink:BiologicalProcess cellular response to amphetamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_0071419 CL:0002015 biolink:Cell Kit-negative, Ly-76 high polychromatophilic erythroblast A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative. go-plus.json late basophilic and polychromatophilic erythroblast http://purl.obolibrary.org/obo/CL_0002015 GO:0071418 biolink:BiologicalProcess cellular response to amine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. go-plus.json http://purl.obolibrary.org/obo/GO_0071418 GO:0071417 biolink:BiologicalProcess cellular response to organonitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. go-plus.json cellular response to organic nitrogen http://purl.obolibrary.org/obo/GO_0071417 CL:0002018 biolink:Cell CD71-negative, GlyA-positive orthochromatic erythroblast An erythroblast that is GlyA-positive and CD71-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002018 GO:0071416 biolink:BiologicalProcess cellular response to tropane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine. go-plus.json http://purl.obolibrary.org/obo/GO_0071416 CL:0002017 biolink:Cell Kit-negative, Ly-76 high orthochromatophilic erythroblasts An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative. go-plus.json http://purl.obolibrary.org/obo/CL_0002017 GO:0071415 biolink:BiologicalProcess cellular response to purine-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. go-plus.json cellular response to purine http://purl.obolibrary.org/obo/GO_0071415 GO:0071414 biolink:BiologicalProcess cellular response to methotrexate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. go-plus.json http://purl.obolibrary.org/obo/GO_0071414 CHEBI:25728 biolink:ChemicalSubstance osmolyte go-plus.json http://purl.obolibrary.org/obo/CHEBI_25728 GO:0071413 biolink:BiologicalProcess cellular response to hydroxyisoflavone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071413 GO:0071412 biolink:BiologicalProcess cellular response to genistein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071412 GO:0071411 biolink:BiologicalProcess cellular response to fluoxetine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071411 gocheck_do_not_manually_annotate GO:0071410 biolink:BiologicalProcess cellular response to cyclopentenone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0071410 CL:0002010 biolink:Cell pre-conventional dendritic cell A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. go-plus.json http://purl.obolibrary.org/obo/CL_0002010 GO:0046484 biolink:BiologicalProcess oxazole or thiazole metabolic process The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position. go-plus.json oxazole or thiazole metabolism http://purl.obolibrary.org/obo/GO_0046484 GO:0071440 biolink:BiologicalProcess regulation of histone H3-K14 acetylation Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone. go-plus.json regulation of histone H3 acetylation at K14|regulation of histone H3K14 acetylation http://purl.obolibrary.org/obo/GO_0071440 GO:1900319 biolink:BiologicalProcess negative regulation of methane biosynthetic process from dimethylamine Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine. go-plus.json inhibition of methane biosynthetic process from dimethylamine|down regulation of methane biosynthetic process from dimethylamine|downregulation of methane biosynthetic process from dimethylamine|down-regulation of methane biosynthetic process from dimethylamine http://purl.obolibrary.org/obo/GO_1900319 GO:0046483 biolink:BiologicalProcess heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). go-plus.json heterocycle metabolism http://purl.obolibrary.org/obo/GO_0046483 goslim_pir GO:0046482 biolink:BiologicalProcess para-aminobenzoic acid metabolic process The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins. go-plus.json para-aminobenzoic acid metabolism|PABA metabolic process|4-aminobenzoic acid metabolic process|vitamin Bx metabolic process|p-aminobenzoic acid metabolic process|vitamin Bx metabolism|p-aminobenzoic acid metabolism|4-aminobenzoic acid metabolism|PABA metabolism http://purl.obolibrary.org/obo/GO_0046482 GO:0046481 biolink:MolecularActivity digalactosyldiacylglycerol synthase activity Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP. KEGG_REACTION:R04469|RHEA:10520|Wikipedia:Digalactosyldiacylglycerol_synthase|EC:2.4.1.241|MetaCyc:RXN-1225 go-plus.json UDP-galactose-dependent digalactosyldiacylglycerol synthase activity|UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity|DGDG synthase activity|UDP-galactose-dependent DGDG synthase activity|UDP-galactose:MGDG galactosyltransferase activity|DGD2|DGD1 http://purl.obolibrary.org/obo/GO_0046481 GO:1900316 biolink:BiologicalProcess negative regulation of maltopentaose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport. go-plus.json inhibition of maltopentaose transport|down regulation of maltopentaose transport|downregulation of maltopentaose transport|down-regulation of maltopentaose transport http://purl.obolibrary.org/obo/GO_1900316 GO:0046480 biolink:MolecularActivity galactolipid galactosyltransferase activity Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol. RHEA:15921|EC:2.4.1.184|MetaCyc:RXN-1226 go-plus.json GGGT activity|digalactosyldiacylglycerol synthase activity|DGDG synthase activity|3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity|galactolipid:galactolipid galactosyltransferase activity|galactolipid-galactolipid galactosyltransferase activity|interlipid galactosyltransferase activity http://purl.obolibrary.org/obo/GO_0046480 GO:1900315 biolink:BiologicalProcess regulation of maltopentaose transport Any process that modulates the frequency, rate or extent of maltopentaose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900315 GO:1900318 biolink:BiologicalProcess regulation of methane biosynthetic process from dimethylamine Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_1900318 GO:1900317 biolink:BiologicalProcess positive regulation of maltopentaose transport Any process that activates or increases the frequency, rate or extent of maltopentaose transport. go-plus.json up-regulation of maltopentaose transport|upregulation of maltopentaose transport|up regulation of maltopentaose transport|activation of maltopentaose transport http://purl.obolibrary.org/obo/GO_1900317 GO:1900312 biolink:BiologicalProcess regulation of maltohexaose transport Any process that modulates the frequency, rate or extent of maltohexaose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900312 GO:1900311 biolink:BiologicalProcess positive regulation of maltoheptaose metabolic process Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process. go-plus.json up-regulation of maltoheptaose metabolic process|positive regulation of maltoheptaose metabolism|up regulation of maltoheptaose metabolism|upregulation of maltoheptaose metabolic process|upregulation of maltoheptaose metabolism|up regulation of maltoheptaose metabolic process|activation of maltoheptaose metabolic process|up-regulation of maltoheptaose metabolism|activation of maltoheptaose metabolism http://purl.obolibrary.org/obo/GO_1900311 GO:1900314 biolink:BiologicalProcess positive regulation of maltohexaose transport Any process that activates or increases the frequency, rate or extent of maltohexaose transport. go-plus.json up regulation of maltohexaose transport|upregulation of maltohexaose transport|up-regulation of maltohexaose transport|activation of maltohexaose transport http://purl.obolibrary.org/obo/GO_1900314 GO:0046489 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046489 GO:1900313 biolink:BiologicalProcess negative regulation of maltohexaose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport. go-plus.json down-regulation of maltohexaose transport|downregulation of maltohexaose transport|down regulation of maltohexaose transport|inhibition of maltohexaose transport http://purl.obolibrary.org/obo/GO_1900313 PR:000021195 biolink:Protein peptide YY proteolytic cleavage product A peptide YY that has been processed by proteolytic cleavage. go-plus.json PYY/ClvPrd http://purl.obolibrary.org/obo/PR_000021195 GO:0046488 biolink:BiologicalProcess phosphatidylinositol metabolic process The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. go-plus.json PtdIns metabolic process|phosphoinositide metabolism|phosphatidylinositol metabolism|phosphoinositide metabolic process|PtdIns metabolism http://purl.obolibrary.org/obo/GO_0046488 GO:0046487 biolink:BiologicalProcess glyoxylate metabolic process The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH. go-plus.json glyoxylate metabolism http://purl.obolibrary.org/obo/GO_0046487 GO:1900310 biolink:BiologicalProcess negative regulation of maltoheptaose metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process. go-plus.json inhibition of maltoheptaose metabolic process|negative regulation of maltoheptaose metabolism|down-regulation of maltoheptaose metabolism|downregulation of maltoheptaose metabolism|down regulation of maltoheptaose metabolism|down regulation of maltoheptaose metabolic process|inhibition of maltoheptaose metabolism|downregulation of maltoheptaose metabolic process|down-regulation of maltoheptaose metabolic process http://purl.obolibrary.org/obo/GO_1900310 GO:0046486 biolink:BiologicalProcess glycerolipid metabolic process The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis. go-plus.json glycerolipid metabolism http://purl.obolibrary.org/obo/GO_0046486 GO:0046485 biolink:BiologicalProcess ether lipid metabolic process The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol. Wikipedia:Ether_lipid go-plus.json ether lipid metabolism|plasmalogen metabolic process http://purl.obolibrary.org/obo/GO_0046485 CHEBI:84069 biolink:ChemicalSubstance pentanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_84069 chebi_ph7_3 CHEBI:84067 biolink:ChemicalSubstance tetradecanal go-plus.json http://purl.obolibrary.org/obo/CHEBI_84067 chebi_ph7_3 CHEBI:84066 biolink:ChemicalSubstance stearyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84066 chebi_ph7_3 CHEBI:84065 biolink:ChemicalSubstance arachidyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84065 chebi_ph7_3 CHEBI:84064 biolink:ChemicalSubstance myristyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84064 chebi_ph7_3 CHEBI:84063 biolink:ChemicalSubstance decyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84063 chebi_ph7_3 GO:0071449 biolink:BiologicalProcess cellular response to lipid hydroperoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids. go-plus.json cellular response to LHPO http://purl.obolibrary.org/obo/GO_0071449 CHEBI:84062 biolink:ChemicalSubstance nonyl palmitate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84062 chebi_ph7_3 GO:0071448 biolink:BiologicalProcess cellular response to alkyl hydroperoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0071448 GO:0071447 biolink:BiologicalProcess cellular response to hydroperoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH. go-plus.json http://purl.obolibrary.org/obo/GO_0071447 GO:0071446 biolink:BiologicalProcess cellular response to salicylic acid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus. go-plus.json cellular response to salicylate stimulus http://purl.obolibrary.org/obo/GO_0071446 GO:0071445 biolink:BiologicalProcess obsolete cellular response to protein stimulus OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. go-plus.json cellular response to protein stimulus http://purl.obolibrary.org/obo/GO_0071445 GO:0071444 biolink:BiologicalProcess cellular response to pheromone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. go-plus.json cellular pheromone response http://purl.obolibrary.org/obo/GO_0071444 GO:0071443 biolink:MolecularActivity tDNA binding Binding to DNA sequences encoding transfer RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0071443 GO:0071442 biolink:BiologicalProcess positive regulation of histone H3-K14 acetylation Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone. go-plus.json stimulation of histone H3-K14 acetylation|up-regulation of histone H3-K14 acetylation|positive regulation of histone H3K14 acetylation|activation of histone H3-K14 acetylation|up regulation of histone H3-K14 acetylation|positive regulation of histone H3 acetylation at K14|upregulation of histone H3-K14 acetylation http://purl.obolibrary.org/obo/GO_0071442 GO:0071441 biolink:BiologicalProcess negative regulation of histone H3-K14 acetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone. go-plus.json negative regulation of histone H3K14 acetylation|down-regulation of histone H3-K14 acetylation|downregulation of histone H3-K14 acetylation|negative regulation of histone H3 acetylation at K14|down regulation of histone H3-K14 acetylation|inhibition of histone H3-K14 acetylation http://purl.obolibrary.org/obo/GO_0071441 GO:0046495 biolink:BiologicalProcess nicotinamide riboside metabolic process The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. go-plus.json nicotinamide riboside metabolism|N-ribosylnicotinamide metabolic process http://purl.obolibrary.org/obo/GO_0046495 GO:0046494 biolink:BiologicalProcess rhizobactin 1021 metabolic process The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti. go-plus.json rhizobactin 1021 metabolism http://purl.obolibrary.org/obo/GO_0046494 GO:0046493 biolink:BiologicalProcess lipid A metabolic process The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. go-plus.json lipid A metabolism http://purl.obolibrary.org/obo/GO_0046493 GO:0046492 biolink:BiologicalProcess heme B metabolic process The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. go-plus.json protoheme metabolic process|heme B metabolism|protoheme metabolism|haem B metabolic process|haem B metabolism http://purl.obolibrary.org/obo/GO_0046492 GO:1900327 biolink:BiologicalProcess regulation of mannotriose transport Any process that modulates the frequency, rate or extent of mannotriose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900327 CHEBI:25703 biolink:ChemicalSubstance organic phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25703 GO:0046491 biolink:BiologicalProcess L-methylmalonyl-CoA metabolic process The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals. go-plus.json L-methylmalonyl-CoA metabolism http://purl.obolibrary.org/obo/GO_0046491 GO:1900326 biolink:BiologicalProcess positive regulation of maltotriulose transport Any process that activates or increases the frequency, rate or extent of maltotriulose transport. go-plus.json up regulation of maltotriulose transport|activation of maltotriulose transport|up-regulation of maltotriulose transport|upregulation of maltotriulose transport http://purl.obolibrary.org/obo/GO_1900326 GO:0046490 biolink:BiologicalProcess isopentenyl diphosphate metabolic process The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids. go-plus.json IPP metabolism|isopentenyl pyrophosphate metabolic process|isopentenyl pyrophosphate metabolism|isopentenyl diphosphate metabolism|IPP metabolic process http://purl.obolibrary.org/obo/GO_0046490 goslim_pir CHEBI:25702 biolink:ChemicalSubstance organic peroxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25702 GO:1900329 biolink:BiologicalProcess positive regulation of mannotriose transport Any process that activates or increases the frequency, rate or extent of mannotriose transport. go-plus.json up regulation of mannotriose transport|activation of mannotriose transport|up-regulation of mannotriose transport|upregulation of mannotriose transport http://purl.obolibrary.org/obo/GO_1900329 CHEBI:25701 biolink:ChemicalSubstance organic oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25701 GO:1900328 biolink:BiologicalProcess negative regulation of mannotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport. go-plus.json downregulation of mannotriose transport|down-regulation of mannotriose transport|inhibition of mannotriose transport|down regulation of mannotriose transport http://purl.obolibrary.org/obo/GO_1900328 GO:1900323 biolink:BiologicalProcess positive regulation of maltotetraose transport Any process that activates or increases the frequency, rate or extent of maltotetraose transport. go-plus.json upregulation of maltotetraose transport|up regulation of maltotetraose transport|activation of maltotetraose transport|up-regulation of maltotetraose transport http://purl.obolibrary.org/obo/GO_1900323 GO:1900322 biolink:BiologicalProcess negative regulation of maltotetraose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport. go-plus.json down regulation of maltotetraose transport|downregulation of maltotetraose transport|down-regulation of maltotetraose transport|inhibition of maltotetraose transport http://purl.obolibrary.org/obo/GO_1900322 GO:1900325 biolink:BiologicalProcess negative regulation of maltotriulose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport. go-plus.json down-regulation of maltotriulose transport|inhibition of maltotriulose transport|down regulation of maltotriulose transport|downregulation of maltotriulose transport http://purl.obolibrary.org/obo/GO_1900325 GO:1900324 biolink:BiologicalProcess regulation of maltotriulose transport Any process that modulates the frequency, rate or extent of maltotriulose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900324 GO:0046499 biolink:BiologicalProcess S-adenosylmethioninamine metabolic process The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt. go-plus.json S-adenosylmethioninamine metabolism http://purl.obolibrary.org/obo/GO_0046499 GO:0046498 biolink:BiologicalProcess S-adenosylhomocysteine metabolic process The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine. go-plus.json S-adenosylhomocysteine metabolism http://purl.obolibrary.org/obo/GO_0046498 GO:1900321 biolink:BiologicalProcess regulation of maltotetraose transport Any process that modulates the frequency, rate or extent of maltotetraose transport. go-plus.json http://purl.obolibrary.org/obo/GO_1900321 GO:0046497 biolink:BiologicalProcess nicotinate nucleotide metabolic process The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin). go-plus.json nicotinate nucleotide metabolism http://purl.obolibrary.org/obo/GO_0046497 GO:0046496 biolink:BiologicalProcess nicotinamide nucleotide metabolic process The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide. go-plus.json nicotinamide nucleotide metabolism http://purl.obolibrary.org/obo/GO_0046496 GO:1900320 biolink:BiologicalProcess positive regulation of methane biosynthetic process from dimethylamine Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine. go-plus.json activation of methane biosynthetic process from dimethylamine|up-regulation of methane biosynthetic process from dimethylamine|upregulation of methane biosynthetic process from dimethylamine|up regulation of methane biosynthetic process from dimethylamine http://purl.obolibrary.org/obo/GO_1900320 CHEBI:597326 biolink:ChemicalSubstance pyridoxal 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_597326 chebi_ph7_3 CHEBI:84076 biolink:ChemicalSubstance L-histidine derivative go-plus.json http://purl.obolibrary.org/obo/CHEBI_84076 GO:0071439 biolink:CellularComponent clathrin complex A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface. go-plus.json clathrin triskelion http://purl.obolibrary.org/obo/GO_0071439 GO:0071438 biolink:CellularComponent obsolete invadopodium membrane OBSOLETE. The portion of the plasma membrane surrounding an invadopodium. go-plus.json http://purl.obolibrary.org/obo/GO_0071438 GO:0071437 biolink:CellularComponent obsolete invadopodium OBSOLETE. A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0071437 CHEBI:25707 biolink:ChemicalSubstance organometallic compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25707 CHEBI:84072 biolink:ChemicalSubstance hexadecyl elaidate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84072 chebi_ph7_3 GO:0071436 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071436 CHEBI:25706 biolink:ChemicalSubstance organomercury compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_25706 GO:0071435 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071435 CHEBI:25705 biolink:ChemicalSubstance organochlorine insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25705 GO:0071434 biolink:BiologicalProcess cell chemotaxis to angiotensin The directed movement of a motile cell in response to the presence of angiotensin. go-plus.json angiotensin mediated chemotaxis|angiotensin-mediated cell chemotaxis http://purl.obolibrary.org/obo/GO_0071434 CHEBI:25704 biolink:ChemicalSubstance organic sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_25704 GO:0071433 biolink:BiologicalProcess cell wall repair A process of cell wall organization that results in the restoration of the cell wall following damage. go-plus.json http://purl.obolibrary.org/obo/GO_0071433 GO:0071432 biolink:BiologicalProcess peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion. go-plus.json alpha-factor maturation|a-factor processing (proteolytic)|mating-type peptide pheromone maturation involved in conjugation with cellular fusion|peptide mating pheromone processing involved in conjugation with cellular fusion|peptide mating pheromone formation involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0071432 GO:0071431 biolink:BiologicalProcess tRNA-containing ribonucleoprotein complex export from nucleus The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm. go-plus.json tRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|tRNA-containing RNP export from nucleus|tRNA-containing ribonucleoprotein complex nucleus export|tRNA-containing ribonucleoprotein complex export from cell nucleus http://purl.obolibrary.org/obo/GO_0071431 GO:0071430 biolink:BiologicalProcess pre-miRNA-containing ribonucleoprotein complex export from nucleus The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm. go-plus.json pre-microRNA-containing ribonucleoprotein complex export from nucleus|pre-microRNA-containing RNP export from nucleus|pre-microRNA-containing ribonucleoprotein complex nucleus export|pre-microRNA-containing ribonucleoprotein complex export from cell nucleus|pre-microRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0071430 CHEBI:25708 biolink:ChemicalSubstance organophosphate insecticide go-plus.json http://purl.obolibrary.org/obo/CHEBI_25708 GO:0071462 biolink:BiologicalProcess cellular response to water stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. go-plus.json http://purl.obolibrary.org/obo/GO_0071462 GO:0071461 biolink:BiologicalProcess cellular response to redox state Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. go-plus.json cellular redox signal response http://purl.obolibrary.org/obo/GO_0071461 GO:0071460 biolink:BiologicalProcess cellular response to cell-matrix adhesion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion. go-plus.json http://purl.obolibrary.org/obo/GO_0071460 GO:1900338 biolink:BiologicalProcess positive regulation of methane biosynthetic process from carbon monoxide Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide. go-plus.json up-regulation of methane biosynthetic process from carbon monoxide|upregulation of methane biosynthetic process from carbon monoxide|up regulation of methane biosynthetic process from carbon monoxide|activation of methane biosynthetic process from carbon monoxide http://purl.obolibrary.org/obo/GO_1900338 OIO:hasExactSynonym biolink:OntologyClass has_exact_synonym go-plus.json http://www.geneontology.org/formats/oboInOwl#hasExactSynonym GO:1900337 biolink:BiologicalProcess negative regulation of methane biosynthetic process from carbon monoxide Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide. go-plus.json inhibition of methane biosynthetic process from carbon monoxide|down regulation of methane biosynthetic process from carbon monoxide|downregulation of methane biosynthetic process from carbon monoxide|down-regulation of methane biosynthetic process from carbon monoxide http://purl.obolibrary.org/obo/GO_1900337 GO:1900339 biolink:BiologicalProcess regulation of methane biosynthetic process from formic acid Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1900339 GO:1900334 biolink:BiologicalProcess negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid. go-plus.json downregulation of methane biosynthetic process from 3-(methylthio)propionic acid|down regulation of methane biosynthetic process from 3-(methylthio)propionic acid|inhibition of methane biosynthetic process from 3-(methylthio)propionic acid|down-regulation of methane biosynthetic process from 3-(methylthio)propionic acid http://purl.obolibrary.org/obo/GO_1900334 GO:1900333 biolink:BiologicalProcess regulation of methane biosynthetic process from 3-(methylthio)propionic acid Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1900333 GO:1900336 biolink:BiologicalProcess regulation of methane biosynthetic process from carbon monoxide Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide. go-plus.json http://purl.obolibrary.org/obo/GO_1900336 GO:1900335 biolink:BiologicalProcess positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid. go-plus.json up regulation of methane biosynthetic process from 3-(methylthio)propionic acid|upregulation of methane biosynthetic process from 3-(methylthio)propionic acid|up-regulation of methane biosynthetic process from 3-(methylthio)propionic acid|activation of methane biosynthetic process from 3-(methylthio)propionic acid http://purl.obolibrary.org/obo/GO_1900335 GO:1900330 biolink:BiologicalProcess regulation of methane biosynthetic process from trimethylamine Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine. go-plus.json http://purl.obolibrary.org/obo/GO_1900330 GO:1900332 biolink:BiologicalProcess positive regulation of methane biosynthetic process from trimethylamine Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine. go-plus.json upregulation of methane biosynthetic process from trimethylamine|up-regulation of methane biosynthetic process from trimethylamine|activation of methane biosynthetic process from trimethylamine|up regulation of methane biosynthetic process from trimethylamine http://purl.obolibrary.org/obo/GO_1900332 GO:1900331 biolink:BiologicalProcess negative regulation of methane biosynthetic process from trimethylamine Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine. go-plus.json inhibition of methane biosynthetic process from trimethylamine|down-regulation of methane biosynthetic process from trimethylamine|downregulation of methane biosynthetic process from trimethylamine|down regulation of methane biosynthetic process from trimethylamine http://purl.obolibrary.org/obo/GO_1900331 CHEBI:84087 biolink:ChemicalSubstance human urinary metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_84087 GO:0071469 biolink:BiologicalProcess cellular response to alkaline pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json cellular response to alkalinity|cellular response to basic pH http://purl.obolibrary.org/obo/GO_0071469 GO:0071468 biolink:BiologicalProcess cellular response to acidic pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json cellular response to acidity http://purl.obolibrary.org/obo/GO_0071468 GO:0071467 biolink:BiologicalProcess cellular response to pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. go-plus.json http://purl.obolibrary.org/obo/GO_0071467 CHEBI:84080 biolink:ChemicalSubstance palmityl laurate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84080 chebi_ph7_3 GO:0071466 biolink:BiologicalProcess cellular response to xenobiotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json cellular response to drug http://purl.obolibrary.org/obo/GO_0071466 goslim_chembl GO:0071465 biolink:BiologicalProcess cellular response to desiccation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water. go-plus.json desiccation tolerance http://purl.obolibrary.org/obo/GO_0071465 GO:0071464 biolink:BiologicalProcess cellular response to hydrostatic pressure Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. go-plus.json cellular response to static fluid pressure|cellular response to biomechanical stress http://purl.obolibrary.org/obo/GO_0071464 GO:0071463 biolink:BiologicalProcess cellular response to humidity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere. go-plus.json http://purl.obolibrary.org/obo/GO_0071463 GO:0071451 biolink:BiologicalProcess cellular response to superoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. go-plus.json http://purl.obolibrary.org/obo/GO_0071451 GO:0071450 biolink:BiologicalProcess cellular response to oxygen radical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. go-plus.json http://purl.obolibrary.org/obo/GO_0071450 GO:1900349 biolink:BiologicalProcess negative regulation of methane biosynthetic process from methylamine Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine. go-plus.json down-regulation of methane biosynthetic process from methylamine|inhibition of methane biosynthetic process from methylamine|down regulation of methane biosynthetic process from methylamine|downregulation of methane biosynthetic process from methylamine http://purl.obolibrary.org/obo/GO_1900349 GO:1900348 biolink:BiologicalProcess regulation of methane biosynthetic process from methylamine Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine. go-plus.json http://purl.obolibrary.org/obo/GO_1900348 GO:1900345 biolink:BiologicalProcess regulation of methane biosynthetic process from methanethiol Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol. go-plus.json http://purl.obolibrary.org/obo/GO_1900345 GO:1900344 biolink:BiologicalProcess positive regulation of methane biosynthetic process from dimethyl sulfide Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide. go-plus.json upregulation of methane biosynthetic process from dimethyl sulfide|up-regulation of methane biosynthetic process from dimethyl sulfide|activation of methane biosynthetic process from dimethyl sulfide|up regulation of methane biosynthetic process from dimethyl sulfide http://purl.obolibrary.org/obo/GO_1900344 GO:1900347 biolink:BiologicalProcess positive regulation of methane biosynthetic process from methanethiol Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol. go-plus.json activation of methane biosynthetic process from methanethiol|up regulation of methane biosynthetic process from methanethiol|upregulation of methane biosynthetic process from methanethiol|up-regulation of methane biosynthetic process from methanethiol http://purl.obolibrary.org/obo/GO_1900347 GO:1900346 biolink:BiologicalProcess negative regulation of methane biosynthetic process from methanethiol Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol. go-plus.json down-regulation of methane biosynthetic process from methanethiol|downregulation of methane biosynthetic process from methanethiol|down regulation of methane biosynthetic process from methanethiol|inhibition of methane biosynthetic process from methanethiol http://purl.obolibrary.org/obo/GO_1900346 GO:1900341 biolink:BiologicalProcess positive regulation of methane biosynthetic process from formic acid Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid. go-plus.json upregulation of methane biosynthetic process from formic acid|up regulation of methane biosynthetic process from formic acid|activation of methane biosynthetic process from formic acid|up-regulation of methane biosynthetic process from formic acid http://purl.obolibrary.org/obo/GO_1900341 GO:1900340 biolink:BiologicalProcess negative regulation of methane biosynthetic process from formic acid Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid. go-plus.json down regulation of methane biosynthetic process from formic acid|downregulation of methane biosynthetic process from formic acid|down-regulation of methane biosynthetic process from formic acid|inhibition of methane biosynthetic process from formic acid http://purl.obolibrary.org/obo/GO_1900340 GO:1900343 biolink:BiologicalProcess negative regulation of methane biosynthetic process from dimethyl sulfide Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide. go-plus.json downregulation of methane biosynthetic process from dimethyl sulfide|down regulation of methane biosynthetic process from dimethyl sulfide|inhibition of methane biosynthetic process from dimethyl sulfide|down-regulation of methane biosynthetic process from dimethyl sulfide http://purl.obolibrary.org/obo/GO_1900343 GO:1900342 biolink:BiologicalProcess regulation of methane biosynthetic process from dimethyl sulfide Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide. go-plus.json http://purl.obolibrary.org/obo/GO_1900342 GO:1900350 biolink:BiologicalProcess positive regulation of methane biosynthetic process from methylamine Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine. go-plus.json up regulation of methane biosynthetic process from methylamine|activation of methane biosynthetic process from methylamine|up-regulation of methane biosynthetic process from methylamine|upregulation of methane biosynthetic process from methylamine http://purl.obolibrary.org/obo/GO_1900350 PR:000021170 biolink:Protein parathyroid hormone proteolytic cleavage product A parathyroid hormone that has been processed by proteolytic cleavage. go-plus.json PTH/ClvPrd http://purl.obolibrary.org/obo/PR_000021170 CHEBI:84095 biolink:ChemicalSubstance 2,6-dimethylheptanoyl carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84095 chebi_ph7_3 GO:0071459 biolink:BiologicalProcess protein localization to chromosome, centromeric region Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome. go-plus.json protein localisation to chromosome, centromeric region|protein localization to centromere|protein localization to chromosome, centric region http://purl.obolibrary.org/obo/GO_0071459 GO:0071458 biolink:CellularComponent integral component of cytoplasmic side of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane. go-plus.json integral to cytosolic side of ER membrane|integral to cytosolic leaflet of endoplasmic reticulum membrane|integral to cytosolic side of endoplasmic reticulum membrane|integral to ER membrane, cytosolic side http://purl.obolibrary.org/obo/GO_0071458 CHEBI:84092 biolink:ChemicalSubstance 4-(beta-D-glucopyranuronosyloxy)retinoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84092 GO:0071457 biolink:BiologicalProcess cellular response to ozone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071457 GO:0071456 biolink:BiologicalProcess cellular response to hypoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. go-plus.json cellular response to lowered oxygen tension|cellular response to hypoxic stress http://purl.obolibrary.org/obo/GO_0071456 GO:0071455 biolink:BiologicalProcess cellular response to hyperoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension. go-plus.json cellular response to increased oxygen tension|cellular response to hyperoxic stress http://purl.obolibrary.org/obo/GO_0071455 CHEBI:84090 biolink:ChemicalSubstance hydroxyretinoic glucuronide go-plus.json http://purl.obolibrary.org/obo/CHEBI_84090 GO:0071454 biolink:BiologicalProcess cellular response to anoxia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%. go-plus.json cellular response to anoxic stress|cellular response to anaerobic conditions http://purl.obolibrary.org/obo/GO_0071454 GO:0071453 biolink:BiologicalProcess cellular response to oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. go-plus.json cellular response to oxygen http://purl.obolibrary.org/obo/GO_0071453 GO:0071452 biolink:BiologicalProcess cellular response to singlet oxygen Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst. go-plus.json http://purl.obolibrary.org/obo/GO_0071452 GO:0046602 biolink:BiologicalProcess regulation of mitotic centrosome separation Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0046602 GO:0046601 biolink:BiologicalProcess positive regulation of centriole replication Any process that activates or increases the frequency, rate or extent of centriole replication. go-plus.json upregulation of centriole replication|up regulation of centriole replication|activation of centriole replication|stimulation of centriole replication|up-regulation of centriole replication http://purl.obolibrary.org/obo/GO_0046601 GO:0046600 biolink:BiologicalProcess negative regulation of centriole replication Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication. go-plus.json down regulation of centriole replication|downregulation of centriole replication|down-regulation of centriole replication|inhibition of centriole replication http://purl.obolibrary.org/obo/GO_0046600 GO:0046609 biolink:MolecularActivity obsolete voltage-gated sulfate antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential. go-plus.json prestin|voltage gated sulfate antiporter activity|voltage-sensitive sulphate antiporter activity|voltage-dependent sulfate antiporter activity|voltage-sensitive sulfate antiporter activity http://purl.obolibrary.org/obo/GO_0046609 GO:0046608 biolink:MolecularActivity carotenoid isomerase activity Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids. go-plus.json http://purl.obolibrary.org/obo/GO_0046608 GO:0046607 biolink:BiologicalProcess positive regulation of centrosome cycle Any process that activates or increases the frequency, rate or extent of the centrosome cycle. go-plus.json upregulation of centrosome cycle|stimulation of centrosome cycle|up-regulation of centrosome cycle|activation of centrosome cycle|up regulation of centrosome cycle http://purl.obolibrary.org/obo/GO_0046607 GO:0046606 biolink:BiologicalProcess negative regulation of centrosome cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle. go-plus.json down regulation of centrosome cycle|inhibition of centrosome cycle|down-regulation of centrosome cycle|downregulation of centrosome cycle http://purl.obolibrary.org/obo/GO_0046606 GO:0046605 biolink:BiologicalProcess regulation of centrosome cycle Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation. go-plus.json http://purl.obolibrary.org/obo/GO_0046605 GO:0046604 biolink:BiologicalProcess positive regulation of mitotic centrosome separation Any process that activates or increases the frequency, rate or extent of centrosome separation. go-plus.json up regulation of mitotic centrosome separation|activation of mitotic centrosome separation|stimulation of mitotic centrosome separation|up-regulation of mitotic centrosome separation|upregulation of mitotic centrosome separation http://purl.obolibrary.org/obo/GO_0046604 GO:0046603 biolink:BiologicalProcess negative regulation of mitotic centrosome separation Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation. go-plus.json down-regulation of mitotic centrosome separation|inhibition of mitotic centrosome separation|down regulation of mitotic centrosome separation|downregulation of mitotic centrosome separation http://purl.obolibrary.org/obo/GO_0046603 CHEBI:45296 biolink:ChemicalSubstance hexadecane go-plus.json http://purl.obolibrary.org/obo/CHEBI_45296 chebi_ph7_3 GO:0007009 biolink:BiologicalProcess plasma membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. go-plus.json plasma membrane organisation|plasma membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0007009 goslim_chembl|goslim_generic GO:0022620 biolink:BiologicalProcess vegetative cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube. go-plus.json tube cell differentiation http://purl.obolibrary.org/obo/GO_0022620 GO:0007008 biolink:BiologicalProcess outer mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane. go-plus.json outer mitochondrial membrane organisation|outer mitochondrial membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0007008 GO:0007007 biolink:BiologicalProcess inner mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane. go-plus.json inner mitochondrial membrane organisation|mitochondrial inner membrane organization|inner mitochondrial membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0007007 GO:0022622 biolink:BiologicalProcess root system development The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0022622 GO:0007006 biolink:BiologicalProcess mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. go-plus.json mitochondrial membrane organisation|mitochondrial membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0007006 GO:0022621 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022621 GO:0007005 biolink:BiologicalProcess mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. go-plus.json mitochondrion organization and biogenesis|mitochondria organization|mitochondrion organisation http://purl.obolibrary.org/obo/GO_0007005 goslim_chembl|goslim_yeast|goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe GO:0046613 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046613 GO:0007004 biolink:BiologicalProcess telomere maintenance via telomerase The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase. go-plus.json telomerase-dependent telomere maintenance http://purl.obolibrary.org/obo/GO_0007004 GO:0046612 biolink:CellularComponent lysosomal proton-transporting V-type ATPase, V1 domain The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane. go-plus.json lysosomal hydrogen ion-transporting ATPase V1 domain http://purl.obolibrary.org/obo/GO_0046612 CHEBI:127343 biolink:ChemicalSubstance 17-(4-hydroxyphenyl)heptadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_127343 GO:0007003 biolink:BiologicalProcess obsolete telomere binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json telomere binding http://purl.obolibrary.org/obo/GO_0007003 GO:0046611 biolink:CellularComponent lysosomal proton-transporting V-type ATPase complex A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen. go-plus.json lysosomal hydrogen-translocating V-type ATPase complex|lysosomal membrane hydrogen-transporting ATPase http://purl.obolibrary.org/obo/GO_0046611 GO:0007002 biolink:BiologicalProcess obsolete centromere binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json centromere binding http://purl.obolibrary.org/obo/GO_0007002 GO:0046610 biolink:CellularComponent lysosomal proton-transporting V-type ATPase, V0 domain The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane. go-plus.json lysosomal hydrogen ion-transporting ATPase V0 domain http://purl.obolibrary.org/obo/GO_0046610 GO:0007001 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007001 GO:0007000 biolink:BiologicalProcess nucleolus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. go-plus.json nucleolus organisation|nucleolus organization and biogenesis http://purl.obolibrary.org/obo/GO_0007000 GO:0046619 biolink:BiologicalProcess lens placode formation involved in camera-type eye formation Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles. go-plus.json optic placode formation involved in camera-type eye formation|optic placode formation involved in camera-style eye|optic placode formation in camera-type eye http://purl.obolibrary.org/obo/GO_0046619 GO:0046618 biolink:BiologicalProcess xenobiotic export The directed movement of a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. go-plus.json drug export http://purl.obolibrary.org/obo/GO_0046618 GO:0046617 biolink:BiologicalProcess obsolete nucleolar size increase (sensu Saccharomyces) OBSOLETE. The process of nucleolar expansion, as seen in Saccharomyces. go-plus.json nucleolar size increase (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0046617 CHEBI:142967 biolink:ChemicalSubstance D-histidine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142967 chebi_ph7_3 GO:0046616 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046616 GO:0046615 biolink:BiologicalProcess obsolete re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces) OBSOLETE. The resumption of the Saccharomyces mitotic cell division cycle by pheromone-arrested cells that have not mated. go-plus.json re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0046615 GO:0046614 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046614 GO:0022624 biolink:CellularComponent proteasome accessory complex A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex. go-plus.json http://purl.obolibrary.org/obo/GO_0022624 GO:0022623 biolink:CellularComponent proteasome-activating nucleotidase complex A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner. go-plus.json PAN http://purl.obolibrary.org/obo/GO_0022623 GO:0022626 biolink:CellularComponent cytosolic ribosome A ribosome located in the cytosol. go-plus.json 70S ribosome|80S ribosome http://purl.obolibrary.org/obo/GO_0022626 GO:0022625 biolink:CellularComponent cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol. go-plus.json prokaryotic large ribosomal subunit|60S ribosomal subunit|50S ribosomal subunit|eukaryotic ribosomal LSU http://purl.obolibrary.org/obo/GO_0022625 GO:0022628 biolink:CellularComponent chloroplast large ribosomal subunit The large subunit of a ribosome contained within a chloroplast. go-plus.json chloroplast ribosomal large subunit complex|chloroplast ribosomal LSU complex http://purl.obolibrary.org/obo/GO_0022628 GO:0022627 biolink:CellularComponent cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol. go-plus.json prokaryotic small ribosomal subunit|eukaryotic ribosomal SSU|40S ribosomal subunit|30S ribosomal subunit http://purl.obolibrary.org/obo/GO_0022627 GO:0022629 biolink:CellularComponent chloroplast small ribosomal subunit The small subunit of a ribosome contained within a chloroplast. go-plus.json chloroplast ribosomal SSU complex|chloroplast ribosomal small subunit complex http://purl.obolibrary.org/obo/GO_0022629 CHEBI:45285 biolink:ChemicalSubstance pyrazinecarboxamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_45285 chebi_ph7_3 GO:0022611 biolink:BiologicalProcess dormancy process A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated. go-plus.json multicellular organism dormancy process|spore dormancy process http://purl.obolibrary.org/obo/GO_0022611 GO:0022610 biolink:BiologicalProcess biological adhesion The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions. go-plus.json http://purl.obolibrary.org/obo/GO_0022610 goslim_pir GO:0046624 biolink:MolecularActivity sphingolipid transporter activity Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). Reactome:R-HSA-9695890 go-plus.json http://purl.obolibrary.org/obo/GO_0046624 GO:0046623 biolink:MolecularActivity sphingolipid floppase activity Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. go-plus.json sphingolipid floppase activity (cytosolic to exoplasmic leaftlet)|sphingolipid flippase activity|sphingolipid-translocating ATPase activity http://purl.obolibrary.org/obo/GO_0046623 GO:0046622 biolink:BiologicalProcess positive regulation of organ growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0046622 GO:0046621 biolink:BiologicalProcess negative regulation of organ growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0046621 GO:0046620 biolink:BiologicalProcess regulation of organ growth Any process that modulates the frequency, rate or extent of growth of an organ of an organism. go-plus.json http://purl.obolibrary.org/obo/GO_0046620 GO:0046629 biolink:BiologicalProcess gamma-delta T cell activation The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json gamma-delta T-cell activation|gamma-delta T lymphocyte activation|gamma-delta T-lymphocyte activation http://purl.obolibrary.org/obo/GO_0046629 GO:0046628 biolink:BiologicalProcess positive regulation of insulin receptor signaling pathway Any process that increases the frequency, rate or extent of insulin receptor signaling. go-plus.json upregulation of insulin receptor signaling pathway|stimulation of insulin receptor signaling pathway|positive regulation of insulin receptor signalling pathway|activation of insulin receptor signaling pathway|up-regulation of insulin receptor signaling pathway|up regulation of insulin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0046628 GO:0046627 biolink:BiologicalProcess negative regulation of insulin receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling. go-plus.json downregulation of insulin receptor signaling pathway|down regulation of insulin receptor signaling pathway|inhibition of insulin receptor signaling pathway|negative regulation of insulin receptor signalling pathway|down-regulation of insulin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0046627 GO:0046626 biolink:BiologicalProcess regulation of insulin receptor signaling pathway Any process that modulates the frequency, rate or extent of insulin receptor signaling. go-plus.json regulation of insulin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0046626 CHEBI:142954 biolink:ChemicalSubstance diacylglycerol 24:0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_142954 chebi_ph7_3 GO:0046625 biolink:MolecularActivity sphingolipid binding Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). go-plus.json http://purl.obolibrary.org/obo/GO_0046625 CHEBI:142953 biolink:ChemicalSubstance didodecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_142953 chebi_ph7_3 GO:0022613 biolink:BiologicalProcess ribonucleoprotein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. go-plus.json ribonucleoprotein complex biogenesis and assembly|RNA-protein complex biogenesis http://purl.obolibrary.org/obo/GO_0022613 GO:0022612 biolink:BiologicalProcess gland morphogenesis The process in which the anatomical structures of a gland are generated and organized. go-plus.json http://purl.obolibrary.org/obo/GO_0022612 GO:0022615 biolink:BiologicalProcess protein to membrane docking The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere. go-plus.json protein-membrane docking http://purl.obolibrary.org/obo/GO_0022615 GO:0022614 biolink:BiologicalProcess membrane to membrane docking The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere. go-plus.json membrane-membrane docking http://purl.obolibrary.org/obo/GO_0022614 GO:0022617 biolink:BiologicalProcess extracellular matrix disassembly A process that results in the breakdown of the extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/GO_0022617 GO:0022616 biolink:BiologicalProcess DNA strand elongation The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. go-plus.json http://purl.obolibrary.org/obo/GO_0022616 GO:0022619 biolink:BiologicalProcess generative cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte. go-plus.json http://purl.obolibrary.org/obo/GO_0022619 GO:0022618 biolink:BiologicalProcess ribonucleoprotein complex assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. go-plus.json RNP complex assembly|RNA-protein complex assembly|protein-RNA complex assembly http://purl.obolibrary.org/obo/GO_0022618 goslim_generic|goslim_chembl GO:1900705 biolink:BiologicalProcess negative regulation of siderophore biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process. go-plus.json down regulation of siderophore synthesis|inhibition of siderochrome biosynthesis|inhibition of siderochrome biosynthetic process|downregulation of siderophore anabolism|down-regulation of siderophore biosynthetic process, peptide modification|negative regulation of siderophore biosynthetic process, peptide modification|down regulation of siderophore formation|downregulation of siderophore synthesis|down-regulation of siderophore biosynthetic process|negative regulation of siderophore biosynthesis|down-regulation of siderophore biosynthesis|inhibition of siderophore biosynthetic process, peptide formation|down regulation of siderochrome biosynthesis|downregulation of siderophore formation|down regulation of siderochrome biosynthetic process|down-regulation of siderophore anabolism|negative regulation of siderophore anabolism|downregulation of siderophore biosynthetic process, peptide modification|downregulation of siderochrome biosynthetic process|downregulation of siderochrome biosynthesis|down-regulation of siderophore synthesis|negative regulation of siderophore synthesis|down regulation of siderophore biosynthetic process, peptide formation|downregulation of siderophore biosynthetic process|down regulation of siderophore biosynthetic process, peptide modification|downregulation of siderophore biosynthesis|down-regulation of siderophore formation|negative regulation of siderophore formation|downregulation of siderophore biosynthetic process, peptide formation|down regulation of siderophore biosynthesis|down regulation of siderophore biosynthetic process|negative regulation of siderochrome biosynthesis|inhibition of siderophore biosynthetic process|negative regulation of siderochrome biosynthetic process|down-regulation of siderochrome biosynthetic process|down-regulation of siderochrome biosynthesis|inhibition of siderophore biosynthetic process, peptide modification|inhibition of siderophore anabolism|inhibition of siderophore biosynthesis|inhibition of siderophore synthesis|negative regulation of siderophore biosynthetic process, peptide formation|down-regulation of siderophore biosynthetic process, peptide formation|down regulation of siderophore anabolism|inhibition of siderophore formation http://purl.obolibrary.org/obo/GO_1900705 GO:1900704 biolink:BiologicalProcess regulation of siderophore biosynthetic process Any process that modulates the frequency, rate or extent of siderophore biosynthetic process. go-plus.json regulation of siderophore synthesis|regulation of siderophore formation|regulation of siderochrome biosynthetic process|regulation of siderochrome biosynthesis|regulation of siderophore biosynthetic process, peptide modification|regulation of siderophore biosynthetic process, peptide formation|regulation of siderophore biosynthesis|regulation of siderophore anabolism http://purl.obolibrary.org/obo/GO_1900704 GO:1900707 biolink:BiologicalProcess regulation of tensidol A biosynthetic process Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process. go-plus.json regulation of tensidol A anabolism|regulation of tensidol A synthesis|regulation of tensidol A formation|regulation of tensidol A biosynthesis http://purl.obolibrary.org/obo/GO_1900707 GO:1900706 biolink:BiologicalProcess positive regulation of siderophore biosynthetic process Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process. go-plus.json activation of siderophore biosynthetic process|up-regulation of siderophore biosynthesis|up-regulation of siderophore biosynthetic process|activation of siderophore biosynthetic process, peptide modification|upregulation of siderophore formation|up-regulation of siderophore biosynthetic process, peptide formation|upregulation of siderochrome biosynthetic process|up regulation of siderophore anabolism|upregulation of siderochrome biosynthesis|activation of siderophore biosynthesis|positive regulation of siderophore biosynthetic process, peptide modification|positive regulation of siderophore anabolism|up regulation of siderophore biosynthetic process, peptide modification|up regulation of siderophore synthesis|positive regulation of siderophore synthesis|positive regulation of siderophore biosynthesis|upregulation of siderophore biosynthetic process, peptide formation|activation of siderophore anabolism|up regulation of siderophore formation|up regulation of siderophore biosynthetic process|up regulation of siderophore biosynthesis|positive regulation of siderophore formation|up regulation of siderochrome biosynthetic process|up regulation of siderochrome biosynthesis|activation of siderophore synthesis|positive regulation of siderochrome biosynthesis|positive regulation of siderochrome biosynthetic process|up-regulation of siderophore anabolism|upregulation of siderophore biosynthetic process, peptide modification|activation of siderophore formation|up regulation of siderophore biosynthetic process, peptide formation|activation of siderochrome biosynthetic process|up-regulation of siderophore synthesis|activation of siderochrome biosynthesis|upregulation of siderophore biosynthesis|upregulation of siderophore biosynthetic process|positive regulation of siderophore biosynthetic process, peptide formation|up-regulation of siderophore formation|upregulation of siderophore anabolism|up-regulation of siderophore biosynthetic process, peptide modification|up-regulation of siderochrome biosynthesis|activation of siderophore biosynthetic process, peptide formation|up-regulation of siderochrome biosynthetic process|upregulation of siderophore synthesis http://purl.obolibrary.org/obo/GO_1900706 GO:1900701 biolink:BiologicalProcess regulation of orcinol biosynthetic process Any process that modulates the frequency, rate or extent of orcinol biosynthetic process. go-plus.json regulation of orcinol anabolism|regulation of orcinol synthesis|regulation of orcinol formation|regulation of orcinol biosynthesis http://purl.obolibrary.org/obo/GO_1900701 GO:1900700 biolink:BiologicalProcess positive regulation of o-orsellinic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process. go-plus.json up-regulation of o-orsellinic acid formation|upregulation of o-orsellinic acid anabolism|upregulation of o-orsellinic acid synthesis|upregulation of o-orsellinic acid biosynthetic process|upregulation of o-orsellinic acid biosynthesis|upregulation of o-orsellinic acid formation|up regulation of o-orsellinic acid anabolism|positive regulation of o-orsellinic acid anabolism|up regulation of o-orsellinic acid synthesis|up-regulation of o-orsellinic acid biosynthetic process|up-regulation of o-orsellinic acid biosynthesis|positive regulation of o-orsellinic acid synthesis|activation of o-orsellinic acid biosynthetic process|activation of o-orsellinic acid anabolism|up regulation of o-orsellinic acid formation|positive regulation of o-orsellinic acid formation|activation of o-orsellinic acid synthesis|activation of o-orsellinic acid biosynthesis|up-regulation of o-orsellinic acid anabolism|activation of o-orsellinic acid formation|positive regulation of o-orsellinic acid biosynthesis|up-regulation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid biosynthetic process|up regulation of o-orsellinic acid biosynthesis http://purl.obolibrary.org/obo/GO_1900700 GO:1900703 biolink:BiologicalProcess positive regulation of orcinol biosynthetic process Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process. go-plus.json positive regulation of orcinol formation|upregulation of orcinol biosynthetic process|upregulation of orcinol biosynthesis|activation of orcinol synthesis|up-regulation of orcinol anabolism|activation of orcinol formation|up-regulation of orcinol synthesis|up-regulation of orcinol biosynthetic process|activation of orcinol biosynthetic process|up-regulation of orcinol biosynthesis|up-regulation of orcinol formation|upregulation of orcinol anabolism|activation of orcinol biosynthesis|upregulation of orcinol synthesis|upregulation of orcinol formation|positive regulation of orcinol biosynthesis|up regulation of orcinol anabolism|up regulation of orcinol biosynthesis|up regulation of orcinol biosynthetic process|positive regulation of orcinol anabolism|up regulation of orcinol synthesis|positive regulation of orcinol synthesis|activation of orcinol anabolism|up regulation of orcinol formation http://purl.obolibrary.org/obo/GO_1900703 GO:0022600 biolink:BiologicalProcess digestive system process A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0022600 GO:1900702 biolink:BiologicalProcess negative regulation of orcinol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process. go-plus.json inhibition of orcinol biosynthetic process|negative regulation of orcinol synthesis|down-regulation of orcinol synthesis|down-regulation of orcinol formation|negative regulation of orcinol formation|inhibition of orcinol biosynthesis|inhibition of orcinol anabolism|inhibition of orcinol synthesis|inhibition of orcinol formation|down regulation of orcinol anabolism|down-regulation of orcinol biosynthetic process|down-regulation of orcinol biosynthesis|negative regulation of orcinol biosynthesis|down regulation of orcinol synthesis|downregulation of orcinol anabolism|down regulation of orcinol formation|downregulation of orcinol synthesis|downregulation of orcinol biosynthesis|downregulation of orcinol biosynthetic process|downregulation of orcinol formation|down-regulation of orcinol anabolism|negative regulation of orcinol anabolism|down regulation of orcinol biosynthesis|down regulation of orcinol biosynthetic process http://purl.obolibrary.org/obo/GO_1900702 GO:0046635 biolink:BiologicalProcess positive regulation of alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation. go-plus.json positive regulation of alpha-beta T-lymphocyte activation|upregulation of alpha-beta T cell activation|positive regulation of alpha-beta T-cell activation|stimulation of alpha-beta T cell activation|up-regulation of alpha-beta T cell activation|activation of alpha-beta T cell activation|positive regulation of alpha-beta T lymphocyte activation|up regulation of alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046635 GO:0046634 biolink:BiologicalProcess regulation of alpha-beta T cell activation Any process that modulates the frequency, rate or extent of alpha-beta T cell activation. go-plus.json regulation of alpha-beta T-lymphocyte activation|regulation of alpha-beta T-cell activation|regulation of alpha-beta T lymphocyte activation http://purl.obolibrary.org/obo/GO_0046634 CHEBI:142940 biolink:ChemicalSubstance dihexadecanoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_142940 chebi_ph7_3 GO:0046633 biolink:BiologicalProcess alpha-beta T cell proliferation The expansion of an alpha-beta T cell population by cell division. go-plus.json alpha-beta T lymphocyte proliferation|alpha-beta T-cell proliferation|alpha-beta T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046633 GO:0046632 biolink:BiologicalProcess alpha-beta T cell differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex. go-plus.json alpha-beta T cell development|alpha-beta T lymphocyte differentiation|alpha-beta T-cell differentiation|alpha-beta T-lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0046632 GO:0046631 biolink:BiologicalProcess alpha-beta T cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. go-plus.json alpha-beta T lymphocyte activation|alpha-beta T-lymphocyte activation|alpha-beta T-cell activation http://purl.obolibrary.org/obo/GO_0046631 GO:0046630 biolink:BiologicalProcess gamma-delta T cell proliferation The expansion of a gamma-delta T cell population by cell division. go-plus.json gamma-delta T-cell proliferation|gamma-delta T-lymphocyte proliferation|gamma-delta T lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046630 GO:0022609 biolink:BiologicalProcess multicellular organism adhesion to substrate The attachment of a multicellular organism to a surface or material. go-plus.json http://purl.obolibrary.org/obo/GO_0022609 GO:0046639 biolink:BiologicalProcess negative regulation of alpha-beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation. go-plus.json negative regulation of alpha-beta T cell development|down-regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T lymphocyte differentiation|inhibition of alpha-beta T cell differentiation|negative regulation of alpha-beta T-cell differentiation|down regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T-lymphocyte differentiation|downregulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046639 GO:0046638 biolink:BiologicalProcess positive regulation of alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation. go-plus.json activation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell development|stimulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T lymphocyte differentiation|up-regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-cell differentiation|upregulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-lymphocyte differentiation|up regulation of alpha-beta T cell differentiation http://purl.obolibrary.org/obo/GO_0046638 GO:0046637 biolink:BiologicalProcess regulation of alpha-beta T cell differentiation Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation. go-plus.json regulation of alpha-beta T-cell differentiation|regulation of alpha-beta T-lymphocyte differentiation|regulation of alpha-beta T cell development|regulation of alpha-beta T lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0046637 GO:0046636 biolink:BiologicalProcess negative regulation of alpha-beta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation. go-plus.json down regulation of alpha-beta T cell activation|negative regulation of alpha-beta T-cell activation|inhibition of alpha-beta T cell activation|negative regulation of alpha-beta T lymphocyte activation|down-regulation of alpha-beta T cell activation|negative regulation of alpha-beta T-lymphocyte activation|downregulation of alpha-beta T cell activation http://purl.obolibrary.org/obo/GO_0046636 GO:0022602 biolink:BiologicalProcess ovulation cycle process A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. go-plus.json estrous cycle process|menstrual cycle process http://purl.obolibrary.org/obo/GO_0022602 GO:0022601 biolink:BiologicalProcess menstrual cycle phase The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur. go-plus.json http://purl.obolibrary.org/obo/GO_0022601 gocheck_do_not_annotate GO:0022604 biolink:BiologicalProcess regulation of cell morphogenesis Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. go-plus.json regulation of cell shape and cell size|negative regulation of cell shape and cell size|positive regulation of cell shape and cell size http://purl.obolibrary.org/obo/GO_0022604 GO:0022603 biolink:BiologicalProcess regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. go-plus.json regulation of morphogenesis http://purl.obolibrary.org/obo/GO_0022603 GO:1900709 biolink:BiologicalProcess positive regulation of tensidol A biosynthetic process Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process. go-plus.json up regulation of tensidol A synthesis|positive regulation of tensidol A formation|up-regulation of tensidol A biosynthetic process|up-regulation of tensidol A biosynthesis|up regulation of tensidol A formation|upregulation of tensidol A anabolism|upregulation of tensidol A synthesis|upregulation of tensidol A biosynthetic process|upregulation of tensidol A biosynthesis|upregulation of tensidol A formation|up-regulation of tensidol A anabolism|up-regulation of tensidol A synthesis|activation of tensidol A anabolism|up regulation of tensidol A biosynthetic process|up regulation of tensidol A biosynthesis|up-regulation of tensidol A formation|activation of tensidol A biosynthetic process|positive regulation of tensidol A biosynthesis|activation of tensidol A synthesis|positive regulation of tensidol A anabolism|up regulation of tensidol A anabolism|activation of tensidol A formation|activation of tensidol A biosynthesis|positive regulation of tensidol A synthesis http://purl.obolibrary.org/obo/GO_1900709 GO:0022606 biolink:BiologicalProcess establishment of proximal/distal cell polarity The specification and formation of the polarity of a cell along its proximal/distal axis. go-plus.json http://purl.obolibrary.org/obo/GO_0022606 GO:1900708 biolink:BiologicalProcess negative regulation of tensidol A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process. go-plus.json downregulation of tensidol A anabolism|inhibition of tensidol A biosynthetic process|down regulation of tensidol A anabolism|downregulation of tensidol A synthesis|downregulation of tensidol A formation|down regulation of tensidol A synthesis|inhibition of tensidol A biosynthesis|inhibition of tensidol A anabolism|down regulation of tensidol A formation|inhibition of tensidol A synthesis|down regulation of tensidol A biosynthesis|down regulation of tensidol A biosynthetic process|inhibition of tensidol A formation|downregulation of tensidol A biosynthetic process|downregulation of tensidol A biosynthesis|negative regulation of tensidol A anabolism|down-regulation of tensidol A anabolism|negative regulation of tensidol A synthesis|down-regulation of tensidol A synthesis|down-regulation of tensidol A biosynthetic process|down-regulation of tensidol A biosynthesis|negative regulation of tensidol A biosynthesis|negative regulation of tensidol A formation|down-regulation of tensidol A formation http://purl.obolibrary.org/obo/GO_1900708 GO:0022605 biolink:BiologicalProcess mammalian oogenesis stage A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. go-plus.json mammalian oogenesis process http://purl.obolibrary.org/obo/GO_0022605 GO:0022608 biolink:BiologicalProcess multicellular organism adhesion The attachment of a multicellular organism to a substrate or other organism. go-plus.json http://purl.obolibrary.org/obo/GO_0022608 GO:0022607 biolink:BiologicalProcess cellular component assembly The aggregation, arrangement and bonding together of a cellular component. go-plus.json cell structure assembly|cellular component assembly at cellular level http://purl.obolibrary.org/obo/GO_0022607 goslim_chembl|goslim_pir|goslim_generic GO:1900716 biolink:BiologicalProcess regulation of violaceol II biosynthetic process Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process. go-plus.json regulation of violaceol II biosynthesis|regulation of violaceol II anabolism|regulation of violaceol II synthesis|regulation of violaceol II formation http://purl.obolibrary.org/obo/GO_1900716 GO:1900715 biolink:BiologicalProcess positive regulation of violaceol I biosynthetic process Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process. go-plus.json up-regulation of violaceol I synthesis|up-regulation of violaceol I formation|upregulation of violaceol I anabolism|upregulation of violaceol I biosynthetic process|upregulation of violaceol I biosynthesis|upregulation of violaceol I synthesis|upregulation of violaceol I formation|up regulation of violaceol I anabolism|activation of violaceol I biosynthetic process|up-regulation of violaceol I biosynthesis|up-regulation of violaceol I biosynthetic process|positive regulation of violaceol I anabolism|up regulation of violaceol I synthesis|positive regulation of violaceol I synthesis|activation of violaceol I biosynthesis|up regulation of violaceol I formation|activation of violaceol I anabolism|positive regulation of violaceol I formation|activation of violaceol I synthesis|positive regulation of violaceol I biosynthesis|up-regulation of violaceol I anabolism|up regulation of violaceol I biosynthesis|up regulation of violaceol I biosynthetic process|activation of violaceol I formation http://purl.obolibrary.org/obo/GO_1900715 SO:0001055 biolink:SequenceFeature transcriptional_cis_regulatory_region A regulatory_region that modulates the transcription of a gene or genes. go-plus.json transcription-control region|transcriptional cis regulatory region|INSDC_qualifier:transcriptional_cis_regulatory_region|INSDC_feature:regulatory http://purl.obolibrary.org/obo/SO_0001055 SOFA GO:1900718 biolink:BiologicalProcess positive regulation of violaceol II biosynthetic process Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process. go-plus.json up-regulation of violaceol II synthesis|activation of violaceol II anabolism|up-regulation of violaceol II formation|up regulation of violaceol II biosynthesis|up regulation of violaceol II biosynthetic process|activation of violaceol II synthesis|activation of violaceol II biosynthetic process|positive regulation of violaceol II anabolism|positive regulation of violaceol II biosynthesis|up regulation of violaceol II anabolism|activation of violaceol II formation|positive regulation of violaceol II synthesis|activation of violaceol II biosynthesis|up regulation of violaceol II synthesis|positive regulation of violaceol II formation|up regulation of violaceol II formation|up-regulation of violaceol II biosynthetic process|up-regulation of violaceol II biosynthesis|upregulation of violaceol II anabolism|upregulation of violaceol II synthesis|upregulation of violaceol II formation|upregulation of violaceol II biosynthetic process|upregulation of violaceol II biosynthesis|up-regulation of violaceol II anabolism http://purl.obolibrary.org/obo/GO_1900718 GO:1900717 biolink:BiologicalProcess negative regulation of violaceol II biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process. go-plus.json downregulation of violaceol II biosynthetic process|downregulation of violaceol II biosynthesis|down-regulation of violaceol II anabolism|negative regulation of violaceol II anabolism|down-regulation of violaceol II synthesis|negative regulation of violaceol II synthesis|down-regulation of violaceol II formation|negative regulation of violaceol II formation|negative regulation of violaceol II biosynthesis|down-regulation of violaceol II biosynthesis|down-regulation of violaceol II biosynthetic process|downregulation of violaceol II anabolism|downregulation of violaceol II synthesis|down regulation of violaceol II anabolism|inhibition of violaceol II biosynthetic process|downregulation of violaceol II formation|down regulation of violaceol II synthesis|inhibition of violaceol II biosynthesis|down regulation of violaceol II formation|inhibition of violaceol II anabolism|inhibition of violaceol II synthesis|down regulation of violaceol II biosynthetic process|down regulation of violaceol II biosynthesis|inhibition of violaceol II formation http://purl.obolibrary.org/obo/GO_1900717 GO:1900712 biolink:BiologicalProcess positive regulation of tensidol B biosynthetic process Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process. go-plus.json activation of tensidol B anabolism|up-regulation of tensidol B formation|up regulation of tensidol B biosynthesis|up regulation of tensidol B biosynthetic process|activation of tensidol B synthesis|positive regulation of tensidol B anabolism|positive regulation of tensidol B biosynthesis|activation of tensidol B biosynthetic process|activation of tensidol B formation|up regulation of tensidol B anabolism|positive regulation of tensidol B synthesis|activation of tensidol B biosynthesis|up regulation of tensidol B synthesis|positive regulation of tensidol B formation|up regulation of tensidol B formation|up-regulation of tensidol B biosynthesis|up-regulation of tensidol B biosynthetic process|upregulation of tensidol B anabolism|upregulation of tensidol B synthesis|upregulation of tensidol B formation|upregulation of tensidol B biosynthesis|upregulation of tensidol B biosynthetic process|up-regulation of tensidol B anabolism|up-regulation of tensidol B synthesis http://purl.obolibrary.org/obo/GO_1900712 GO:1900711 biolink:BiologicalProcess negative regulation of tensidol B biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process. go-plus.json downregulation of tensidol B biosynthesis|downregulation of tensidol B biosynthetic process|negative regulation of tensidol B anabolism|down-regulation of tensidol B anabolism|negative regulation of tensidol B synthesis|down-regulation of tensidol B synthesis|negative regulation of tensidol B formation|down-regulation of tensidol B formation|down-regulation of tensidol B biosynthetic process|down-regulation of tensidol B biosynthesis|negative regulation of tensidol B biosynthesis|downregulation of tensidol B anabolism|down regulation of tensidol B anabolism|downregulation of tensidol B synthesis|inhibition of tensidol B biosynthetic process|downregulation of tensidol B formation|down regulation of tensidol B synthesis|inhibition of tensidol B anabolism|inhibition of tensidol B biosynthesis|down regulation of tensidol B formation|inhibition of tensidol B synthesis|down regulation of tensidol B biosynthetic process|inhibition of tensidol B formation|down regulation of tensidol B biosynthesis http://purl.obolibrary.org/obo/GO_1900711 GO:1900714 biolink:BiologicalProcess negative regulation of violaceol I biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process. go-plus.json downregulation of violaceol I biosynthetic process|downregulation of violaceol I biosynthesis|inhibition of violaceol I anabolism|down regulation of violaceol I biosynthesis|down regulation of violaceol I biosynthetic process|inhibition of violaceol I synthesis|inhibition of violaceol I biosynthetic process|inhibition of violaceol I formation|down regulation of violaceol I anabolism|inhibition of violaceol I biosynthesis|downregulation of violaceol I anabolism|down regulation of violaceol I synthesis|down regulation of violaceol I formation|downregulation of violaceol I synthesis|downregulation of violaceol I formation|negative regulation of violaceol I anabolism|down-regulation of violaceol I anabolism|down-regulation of violaceol I biosynthesis|down-regulation of violaceol I biosynthetic process|negative regulation of violaceol I biosynthesis|negative regulation of violaceol I synthesis|down-regulation of violaceol I synthesis|negative regulation of violaceol I formation|down-regulation of violaceol I formation http://purl.obolibrary.org/obo/GO_1900714 GO:1900713 biolink:BiologicalProcess regulation of violaceol I biosynthetic process Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process. go-plus.json regulation of violaceol I biosynthesis|regulation of violaceol I anabolism|regulation of violaceol I synthesis|regulation of violaceol I formation http://purl.obolibrary.org/obo/GO_1900713 OIO:hasSynonymType biolink:OntologyClass has_synonym_type go-plus.json http://www.geneontology.org/formats/oboInOwl#hasSynonymType GO:0046646 biolink:BiologicalProcess regulation of gamma-delta T cell proliferation Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation. go-plus.json regulation of gamma-delta T-cell proliferation|regulation of gamma-delta T-lymphocyte proliferation|regulation of gamma-delta T lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046646 GO:0046645 biolink:BiologicalProcess positive regulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation. go-plus.json positive regulation of gamma-delta T lymphocyte activation|up regulation of gamma-delta T cell activation|activation of gamma-delta T cell activation|stimulation of gamma-delta T cell activation|positive regulation of gamma-delta T-lymphocyte activation|up-regulation of gamma-delta T cell activation|positive regulation of gamma-delta T-cell activation|upregulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0046645 GO:1900710 biolink:BiologicalProcess regulation of tensidol B biosynthetic process Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process. go-plus.json regulation of tensidol B anabolism|regulation of tensidol B synthesis|regulation of tensidol B formation|regulation of tensidol B biosynthesis http://purl.obolibrary.org/obo/GO_1900710 GO:0046644 biolink:BiologicalProcess negative regulation of gamma-delta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation. go-plus.json downregulation of gamma-delta T cell activation|negative regulation of gamma-delta T lymphocyte activation|down-regulation of gamma-delta T cell activation|inhibition of gamma-delta T cell activation|negative regulation of gamma-delta T-lymphocyte activation|negative regulation of gamma-delta T-cell activation|down regulation of gamma-delta T cell activation http://purl.obolibrary.org/obo/GO_0046644 CHEBI:21291 biolink:ChemicalSubstance L-fuconate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21291 chebi_ph7_3 GO:0046643 biolink:BiologicalProcess regulation of gamma-delta T cell activation Any process that modulates the frequency, rate or extent of gamma-delta T cell activation. go-plus.json regulation of gamma-delta T-lymphocyte activation|regulation of gamma-delta T-cell activation|regulation of gamma-delta T lymphocyte activation http://purl.obolibrary.org/obo/GO_0046643 GO:0046642 biolink:BiologicalProcess negative regulation of alpha-beta T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation. go-plus.json downregulation of alpha-beta T cell proliferation|negative regulation of alpha-beta T-lymphocyte proliferation|down-regulation of alpha-beta T cell proliferation|negative regulation of alpha-beta T lymphocyte proliferation|inhibition of alpha-beta T cell proliferation|negative regulation of alpha-beta T-cell proliferation|down regulation of alpha-beta T cell proliferation http://purl.obolibrary.org/obo/GO_0046642 GO:0046641 biolink:BiologicalProcess positive regulation of alpha-beta T cell proliferation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation. go-plus.json up regulation of alpha-beta T cell proliferation|activation of alpha-beta T cell proliferation|stimulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T lymphocyte proliferation|up-regulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T-cell proliferation|upregulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046641 GO:0046640 biolink:BiologicalProcess regulation of alpha-beta T cell proliferation Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation. go-plus.json regulation of alpha-beta T lymphocyte proliferation|regulation of alpha-beta T-cell proliferation|regulation of alpha-beta T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046640 CHEBI:142938 biolink:ChemicalSubstance gentamycin 2''-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_142938 GO:0071609 biolink:BiologicalProcess chemokine (C-C motif) ligand 5 production The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json Regulated upon Activation, Normal T-cell Expressed, and Secreted production|CCL5 production|RANTES production http://purl.obolibrary.org/obo/GO_0071609 gocheck_do_not_annotate GO:0071608 biolink:BiologicalProcess macrophage inflammatory protein-1 alpha production The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json macrophage inflammatory protein production|chemokine (C-C motif) ligand 3 production|CCL3 production|MIP-1a production http://purl.obolibrary.org/obo/GO_0071608 gocheck_do_not_annotate GO:0071607 biolink:BiologicalProcess macrophage inflammatory protein-1 gamma production The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json chemokine (C-C motif) ligand 9 production|CCL9 production|MIP-1g production http://purl.obolibrary.org/obo/GO_0071607 gocheck_do_not_annotate GO:0071606 biolink:BiologicalProcess chemokine (C-C motif) ligand 4 production The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json macrophage inflammatory protein production|CCL4 production|MIP-1b production http://purl.obolibrary.org/obo/GO_0071606 gocheck_do_not_annotate GO:0071605 biolink:BiologicalProcess monocyte chemotactic protein-1 production The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CCL2 production|MCP-1 production http://purl.obolibrary.org/obo/GO_0071605 gocheck_do_not_annotate GO:0046649 biolink:BiologicalProcess lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. go-plus.json http://purl.obolibrary.org/obo/GO_0046649 CHEBI:166988 biolink:ChemicalSubstance glycerophosphoglycerophosphoglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_166988 GO:0071604 biolink:BiologicalProcess transforming growth factor beta production The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3. go-plus.json TGF-B production|transforming growth factor-beta production|TGFbeta production|transforming growth factor-beta secretion|TGFb production|TGF-beta production http://purl.obolibrary.org/obo/GO_0071604 GO:0046648 biolink:BiologicalProcess positive regulation of gamma-delta T cell proliferation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation. go-plus.json up regulation of gamma-delta T cell proliferation|positive regulation of gamma-delta T lymphocyte proliferation|upregulation of gamma-delta T cell proliferation|positive regulation of gamma-delta T-cell proliferation|stimulation of gamma-delta T cell proliferation|up-regulation of gamma-delta T cell proliferation|activation of gamma-delta T cell proliferation|positive regulation of gamma-delta T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046648 GO:0046647 biolink:BiologicalProcess negative regulation of gamma-delta T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation. go-plus.json down-regulation of gamma-delta T cell proliferation|negative regulation of gamma-delta T lymphocyte proliferation|downregulation of gamma-delta T cell proliferation|down regulation of gamma-delta T cell proliferation|inhibition of gamma-delta T cell proliferation|negative regulation of gamma-delta T-cell proliferation|negative regulation of gamma-delta T-lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0046647 GO:0071603 biolink:BiologicalProcess endothelial cell-cell adhesion The attachment of an endothelial cell to another endothelial cell via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0071603 GO:0071602 biolink:BiologicalProcess phytosphingosine biosynthetic process The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol. go-plus.json phytosphingosine biosynthesis|phytosphingosine anabolism|phytosphingosine synthesis|phytosphingosine formation http://purl.obolibrary.org/obo/GO_0071602 UBERON:0002203 biolink:AnatomicalEntity vasculature of eye Vasculature that is part of the eye region. go-plus.json eye vasculature|optic vasculature|eye vascular network|ocular blood vessel|ocular vasculature|vascular network of eye http://purl.obolibrary.org/obo/UBERON_0002203 UBERON:0002202 biolink:AnatomicalEntity submucosa of trachea A submucosa that is part of a trachea. go-plus.json submucous layer of trachea|tracheal submucosa|trachea submucosa|submucosa of windpipe|windpipe submucosa http://purl.obolibrary.org/obo/UBERON_0002202 GO:0071601 biolink:CellularComponent sphere organelle A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0071601 GO:0071600 biolink:BiologicalProcess otic vesicle morphogenesis The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. go-plus.json http://purl.obolibrary.org/obo/GO_0071600 UBERON:0002204 biolink:AnatomicalEntity musculoskeletal system Anatomical system that consists of the muscular and skeletal systems. go-plus.json musculo-skeletal system http://purl.obolibrary.org/obo/UBERON_0002204 GO:1900719 biolink:BiologicalProcess regulation of uterine smooth muscle relaxation Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation. go-plus.json regulation of smooth muscle relaxation of the uterus http://purl.obolibrary.org/obo/GO_1900719 UBERON:0002201 biolink:AnatomicalEntity vasculature of trunk A vasculature that is part of a trunk [Automatically generated definition]. go-plus.json vasculature of torso|torso vascular network|trunk vascular network|vascular network of trunk|vascular network of torso|trunk vasculature|torso vasculature http://purl.obolibrary.org/obo/UBERON_0002201 UBERON:0002200 biolink:AnatomicalEntity vasculature of head Vasculature that is part of a head [Automatically generated definition]. go-plus.json vasculature of adult head|head vascular network|adult head vascular network|adult head vasculature|vascular network of adult head|head vasculature|cranial vasculature|vascular network of head http://purl.obolibrary.org/obo/UBERON_0002200 GO:1900727 biolink:BiologicalProcess osmoregulated periplasmic glucan biosynthetic process The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan. go-plus.json osmoregulated periplasmic glucan anabolism|osmoregulated periplasmic glucan biosynthesis|osmoregulated periplasmic glucan synthesis|osmoregulated periplasmic glucan formation http://purl.obolibrary.org/obo/GO_1900727 GO:1900726 biolink:BiologicalProcess osmoregulated periplasmic glucan catabolic process The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan. go-plus.json osmoregulated periplasmic glucan catabolism|osmoregulated periplasmic glucan degradation|osmoregulated periplasmic glucan breakdown http://purl.obolibrary.org/obo/GO_1900726 GO:1900729 biolink:BiologicalProcess regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway. go-plus.json regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway|regulation of opioid receptor-mediated adenylate cyclase inhibition|regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|regulation of inhibition of adenylate cyclase activity by opioid receptor http://purl.obolibrary.org/obo/GO_1900729 GO:1900728 biolink:BiologicalProcess cardiac neural crest cell delamination involved in outflow tract morphogenesis Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis. go-plus.json http://purl.obolibrary.org/obo/GO_1900728 GO:1900723 biolink:BiologicalProcess negative regulation of protein adenylylation Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation. go-plus.json down regulation of protein adenylylation|downregulation of protein amino acid adenylylation|downregulation of protein adenylylation|down regulation of protein amino acid adenylylation|downregulation of protein AMPylation|inhibition of protein adenylation|down regulation of protein AMPylation|inhibition of protein amino acid adenylylation|down regulation of protein adenylation|down-regulation of protein adenylylation|inhibition of protein AMPylation|downregulation of protein adenylation|inhibition of protein adenylylation|down-regulation of protein amino acid adenylylation|negative regulation of protein amino acid adenylylation|down-regulation of protein adenylation|negative regulation of protein adenylation|down-regulation of protein AMPylation|negative regulation of protein AMPylation http://purl.obolibrary.org/obo/GO_1900723 GO:1900722 biolink:BiologicalProcess regulation of protein adenylylation Any process that modulates the frequency, rate or extent of protein adenylylation. go-plus.json regulation of protein amino acid adenylylation|regulation of protein AMPylation|regulation of protein adenylation http://purl.obolibrary.org/obo/GO_1900722 GO:1900725 biolink:BiologicalProcess osmoregulated periplasmic glucan metabolic process The chemical reactions and pathways involving osmoregulated periplasmic glucan. go-plus.json osmoregulated periplasmic glucan metabolism http://purl.obolibrary.org/obo/GO_1900725 GO:1900724 biolink:BiologicalProcess positive regulation of protein adenylylation Any process that activates or increases the frequency, rate or extent of protein adenylylation. go-plus.json positive regulation of protein AMPylation|up-regulation of protein adenylation|up regulation of protein AMPylation|up regulation of protein adenylylation|upregulation of protein amino acid adenylylation|activation of protein adenylylation|upregulation of protein adenylation|upregulation of protein AMPylation|up-regulation of protein amino acid adenylylation|up regulation of protein adenylation|up-regulation of protein adenylylation|up-regulation of protein AMPylation|positive regulation of protein adenylation|activation of protein amino acid adenylylation|activation of protein AMPylation|activation of protein adenylation|positive regulation of protein amino acid adenylylation|upregulation of protein adenylylation|up regulation of protein amino acid adenylylation http://purl.obolibrary.org/obo/GO_1900724 GO:0046657 biolink:BiologicalProcess folic acid catabolic process The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid. go-plus.json vitamin M catabolism|folic acid catabolism|folate catabolic process|vitamin B9 catabolism|folic acid degradation|vitamin B9 catabolic process|folic acid breakdown|folate catabolism|vitamin M catabolic process http://purl.obolibrary.org/obo/GO_0046657 GO:0046656 biolink:BiologicalProcess folic acid biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid. Wikipedia:Folic_acid|MetaCyc:FOLSYN-PWY go-plus.json folic acid synthesis|folic acid formation|vitamin M biosynthesis|vitamin M biosynthetic process|folic acid biosynthesis|vitamin B9 biosynthetic process|vitamin B9 biosynthesis|folate biosynthetic process|folate biosynthesis|folic acid anabolism http://purl.obolibrary.org/obo/GO_0046656 GO:1900721 biolink:BiologicalProcess positive regulation of uterine smooth muscle relaxation Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation. go-plus.json up-regulation of uterine smooth muscle relaxation|activation of uterine smooth muscle relaxation|upregulation of smooth muscle relaxation of the uterus|up-regulation of smooth muscle relaxation of the uterus|up regulation of uterine smooth muscle relaxation|activation of smooth muscle relaxation of the uterus|positive regulation of smooth muscle relaxation of the uterus|up regulation of smooth muscle relaxation of the uterus|upregulation of uterine smooth muscle relaxation http://purl.obolibrary.org/obo/GO_1900721 GO:0046655 biolink:BiologicalProcess folic acid metabolic process The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. go-plus.json folate metabolic process|vitamin M metabolism|folic acid metabolism|vitamin B9 metabolic process|vitamin B9 metabolism|vitamin M metabolic process|folate metabolism http://purl.obolibrary.org/obo/GO_0046655 GO:1900720 biolink:BiologicalProcess negative regulation of uterine smooth muscle relaxation Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation. go-plus.json inhibition of smooth muscle relaxation of the uterus|down-regulation of uterine smooth muscle relaxation|downregulation of uterine smooth muscle relaxation|negative regulation of smooth muscle relaxation of the uterus|down-regulation of smooth muscle relaxation of the uterus|down regulation of uterine smooth muscle relaxation|inhibition of uterine smooth muscle relaxation|downregulation of smooth muscle relaxation of the uterus|down regulation of smooth muscle relaxation of the uterus http://purl.obolibrary.org/obo/GO_1900720 GO:0046654 biolink:BiologicalProcess tetrahydrofolate biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. MetaCyc:FOLSYN-PWY go-plus.json tetrahydrofolate anabolism|tetrahydrofolate synthesis|tetrahydrofolate biosynthesis|tetrahydrofolate formation http://purl.obolibrary.org/obo/GO_0046654 GO:0046653 biolink:BiologicalProcess tetrahydrofolate metabolic process The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. go-plus.json tetrahydrofolate metabolism http://purl.obolibrary.org/obo/GO_0046653 CHEBI:45257 biolink:ChemicalSubstance ribostamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_45257 GO:0046652 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046652 GO:0046651 biolink:BiologicalProcess lymphocyte proliferation The expansion of a lymphocyte population by cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0046651 GO:0046650 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046650 CHEBI:59894 biolink:ChemicalSubstance (Z)-3-aminoacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59894 chebi_ph7_3 CHEBI:59893 biolink:ChemicalSubstance (Z)-3-aminoacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59893 CHEBI:59892 biolink:ChemicalSubstance (Z)-3-aminoperacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59892 chebi_ph7_3 CHEBI:59891 biolink:ChemicalSubstance ureidoacrylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59891 chebi_ph7_3 CHEBI:59890 biolink:ChemicalSubstance ureidoacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59890 CHEBI:142921 biolink:ChemicalSubstance 3-phenylprop-2-enal go-plus.json http://purl.obolibrary.org/obo/CHEBI_142921 chebi_ph7_3 GO:0046659 biolink:MolecularActivity digestive hormone activity The action characteristic of a hormone that takes part in the digestion process. go-plus.json secretin http://purl.obolibrary.org/obo/GO_0046659 GO:0046658 biolink:CellularComponent anchored component of plasma membrane The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. go-plus.json plasma membrane, GPI-anchored|anchored to plasma membrane http://purl.obolibrary.org/obo/GO_0046658 CHEBI:59899 biolink:ChemicalSubstance 3-nitropropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59899 chebi_ph7_3 CHEBI:59898 biolink:ChemicalSubstance 3-iodo-L-tyrosine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59898 chebi_ph7_3 CHEBI:59897 biolink:ChemicalSubstance EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_59897 CHEBI:59896 biolink:ChemicalSubstance glutathione amide disulfide dizwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59896 chebi_ph7_3 CHEBI:59895 biolink:ChemicalSubstance glutathione amide zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59895 chebi_ph7_3 GO:1900738 biolink:BiologicalProcess positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway. go-plus.json activation of phospholipase C-activating G-protein coupled receptor signaling pathway|up-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of phospholipase C-activating dopamine receptor signaling pathway|activation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|upregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of PLC-activating GPCR signaling pathway|activation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|positive regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|up-regulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of PLC-activating GPCR signaling pathway|up regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|upregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|activation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of phospholipase C-activating dopamine receptor signaling pathway|up regulation of PLC-activating GPCR signaling pathway|upregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of PLC-activating GPCR signaling pathway|up regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of PLC-activating GPCR signaling pathway http://purl.obolibrary.org/obo/GO_1900738 GO:0046660 biolink:BiologicalProcess female sex differentiation The establishment of the sex of a female organism by physical differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0046660 GO:1900737 biolink:BiologicalProcess negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway. go-plus.json negative regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|downregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|inhibition of phospholipase C-activating dopamine receptor signaling pathway|down-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of PLC-activating GPCR signaling pathway|inhibition of phospholipase C-activating G-protein coupled receptor signaling pathway|negative regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|inhibition of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|negative regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|downregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of PLC-activating GPCR signaling pathway|negative regulation of phospholipase C-activating dopamine receptor signaling pathway|down regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|down-regulation of phospholipase C-activating dopamine receptor signaling pathway|down regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of PLC-activating GPCR signaling pathway|down-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|down regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|inhibition of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of phospholipase C-activating dopamine receptor signaling pathway|inhibition of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of PLC-activating GPCR signaling pathway|negative regulation of PLC-activating GPCR signaling pathway|down regulation of phospholipase C-activating dopamine receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900737 CHEBI:45240 biolink:ChemicalSubstance 1,2-di-O-myristoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_45240 chebi_ph7_3 GO:1900739 biolink:BiologicalProcess regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway. go-plus.json regulation of protein insertion into mitochondrion membrane during induction of apoptosis|regulation of protein insertion into mitochondrial membrane during induction of apoptosis|regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis http://purl.obolibrary.org/obo/GO_1900739 GO:1900734 biolink:BiologicalProcess positive regulation of polyketide biosynthetic process Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process. go-plus.json upregulation of polyketide anabolism|upregulation of polyketide biosynthetic process|upregulation of polyketide biosynthesis|upregulation of polyketide synthesis|upregulation of polyketide formation|up-regulation of polyketide anabolism|up regulation of polyketide biosynthetic process|up regulation of polyketide biosynthesis|activation of polyketide biosynthetic process|positive regulation of polyketide biosynthesis|up-regulation of polyketide synthesis|activation of polyketide anabolism|up-regulation of polyketide formation|activation of polyketide biosynthesis|activation of polyketide synthesis|positive regulation of polyketide anabolism|up regulation of polyketide anabolism|activation of polyketide formation|up-regulation of polyketide biosynthesis|up-regulation of polyketide biosynthetic process|positive regulation of polyketide synthesis|up regulation of polyketide synthesis|positive regulation of polyketide formation|up regulation of polyketide formation http://purl.obolibrary.org/obo/GO_1900734 GO:1900733 biolink:BiologicalProcess negative regulation of polyketide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process. go-plus.json downregulation of polyketide formation|down regulation of polyketide synthesis|down regulation of polyketide biosynthesis|down regulation of polyketide biosynthetic process|down regulation of polyketide formation|inhibition of polyketide anabolism|downregulation of polyketide biosynthetic process|downregulation of polyketide biosynthesis|inhibition of polyketide synthesis|inhibition of polyketide formation|down-regulation of polyketide anabolism|negative regulation of polyketide biosynthesis|down-regulation of polyketide biosynthesis|negative regulation of polyketide anabolism|down-regulation of polyketide biosynthetic process|down-regulation of polyketide synthesis|negative regulation of polyketide synthesis|inhibition of polyketide biosynthetic process|down-regulation of polyketide formation|negative regulation of polyketide formation|downregulation of polyketide anabolism|inhibition of polyketide biosynthesis|down regulation of polyketide anabolism|downregulation of polyketide synthesis http://purl.obolibrary.org/obo/GO_1900733 GO:1900736 biolink:BiologicalProcess regulation of phospholipase C-activating G protein-coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway. go-plus.json regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|regulation of PLC-activating GPCR signaling pathway|regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|regulation of phospholipase C-activating dopamine receptor signaling pathway|regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating) http://purl.obolibrary.org/obo/GO_1900736 GO:1900735 biolink:BiologicalProcess positive regulation of flocculation Any process that activates or increases the frequency, rate or extent of flocculation. go-plus.json upregulation of flocculation|up-regulation of flocculation via cell wall protein-carbohydrate interaction|up-regulation of flocculation|activation of flocculation|upregulation of flocculation via cell wall protein-carbohydrate interaction|positive regulation of flocculation via cell wall protein-carbohydrate interaction|up regulation of flocculation|up regulation of flocculation via cell wall protein-carbohydrate interaction|activation of flocculation via cell wall protein-carbohydrate interaction http://purl.obolibrary.org/obo/GO_1900735 GO:1900730 biolink:BiologicalProcess negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway. go-plus.json negative regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway|negative regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|down-regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|inhibition of opioid receptor-mediated adenylate cyclase inhibition|downregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|down regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|inhibition of adenylate cyclase-inhibiting opioid receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900730 GO:0046668 biolink:BiologicalProcess regulation of retinal cell programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina. go-plus.json regulation of retinal programmed cell death http://purl.obolibrary.org/obo/GO_0046668 GO:0046667 biolink:BiologicalProcess compound eye retinal cell programmed cell death Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium. go-plus.json http://purl.obolibrary.org/obo/GO_0046667 GO:1900732 biolink:BiologicalProcess regulation of polyketide biosynthetic process Any process that modulates the frequency, rate or extent of polyketide biosynthetic process. go-plus.json regulation of polyketide synthesis|regulation of polyketide formation|regulation of polyketide biosynthesis|regulation of polyketide anabolism http://purl.obolibrary.org/obo/GO_1900732 GO:0046666 biolink:BiologicalProcess retinal cell programmed cell death Programmed cell death that occurs in the developing retina. go-plus.json programmed cell death, retinal cells|retinal programmed cell death|retina cell programmed cell death|programmed cell death, retina cells|retina programmed cell death http://purl.obolibrary.org/obo/GO_0046666 GO:1900731 biolink:BiologicalProcess positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway. go-plus.json activation of opioid receptor-mediated adenylate cyclase inhibition|up regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|upregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|activation of adenylate cyclase-inhibiting opioid receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900731 GO:0046665 biolink:BiologicalProcess amnioserosa maintenance Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. go-plus.json http://purl.obolibrary.org/obo/GO_0046665 GO:0046664 biolink:BiologicalProcess dorsal closure, amnioserosa morphology change The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0046664 GO:0046663 biolink:BiologicalProcess dorsal closure, leading edge cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure. go-plus.json http://purl.obolibrary.org/obo/GO_0046663 GO:0046662 biolink:BiologicalProcess regulation of oviposition Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium. go-plus.json regulation of post-mating oviposition http://purl.obolibrary.org/obo/GO_0046662 GO:0046661 biolink:BiologicalProcess male sex differentiation The establishment of the sex of a male organism by physical differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0046661 CHEBI:59881 biolink:ChemicalSubstance keto-D-fructuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59881 chebi_ph7_3 GO:0071629 biolink:BiologicalProcess cytoplasm protein quality control by the ubiquitin-proteasome system The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation. go-plus.json cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism|cytoplasm-associated proteasomal ubiquitin-dependent protein degradation|cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown|ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome http://purl.obolibrary.org/obo/GO_0071629 GO:0071628 biolink:CellularComponent intrinsic component of fungal-type vacuolar membrane The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0071628 GO:0071627 biolink:CellularComponent integral component of fungal-type vacuolar membrane The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. go-plus.json integral to fungal-type vacuolar membrane http://purl.obolibrary.org/obo/GO_0071627 GO:0071626 biolink:BiologicalProcess mastication The process of biting and mashing food with the teeth prior to swallowing. go-plus.json chewing http://purl.obolibrary.org/obo/GO_0071626 GO:0071625 biolink:BiologicalProcess vocalization behavior The behavior in which an organism produces sounds by a mechanism involving its respiratory system. go-plus.json vocalisation behaviour http://purl.obolibrary.org/obo/GO_0071625 GO:0046669 biolink:BiologicalProcess regulation of compound eye retinal cell programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. go-plus.json regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046669 GO:0071624 biolink:BiologicalProcess positive regulation of granulocyte chemotaxis Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071624 GO:0071623 biolink:BiologicalProcess negative regulation of granulocyte chemotaxis Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071623 GO:0071622 biolink:BiologicalProcess regulation of granulocyte chemotaxis Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071622 CHEBI:59889 biolink:ChemicalSubstance ureidoperacrylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59889 chebi_ph7_3 GO:0071621 biolink:BiologicalProcess granulocyte chemotaxis The movement of a granulocyte in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071621 CHEBI:59888 biolink:ChemicalSubstance gamma-aminobutyric acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59888 chebi_ph7_3 GO:0071620 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain serine 5 residues The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans). go-plus.json http://purl.obolibrary.org/obo/GO_0071620 CHEBI:59887 biolink:ChemicalSubstance 2-imino-3-(7-chloroindol-3-yl)propionate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59887 CHEBI:59885 biolink:ChemicalSubstance XTP(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59885 GO:0046671 biolink:BiologicalProcess negative regulation of retinal cell programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina. go-plus.json down regulation of retinal programmed cell death|downregulation of retinal programmed cell death|negative regulation of retinal programmed cell death|down-regulation of retinal programmed cell death|inhibition of retinal programmed cell death http://purl.obolibrary.org/obo/GO_0046671 SO:0001067 biolink:SequenceFeature polypeptide_motif A sequence motif is a short (up to 20 amino acids) region of biological interest. Such motifs, although they are too short to constitute functional domains, share sequence similarities and are conserved in different proteins. They display a common function (protein-binding, subcellular location etc.). go-plus.json polypeptide motif|motif http://purl.obolibrary.org/obo/SO_0001067 biosapiens GO:1900749 biolink:BiologicalProcess (R)-carnitine transport The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json Levocarnitine transport|Carnitor transport|Vitamin BT transport|L-Carnitine transport|Carnitine transport|C7H15NO3 transport|Carnicor transport|Carnitene transport|(3R)-3-hydroxy-4-(trimethylammonio)butanoate transport|(-)-Carnitine transport|(R)-Carnitine transport|(-)-L-Carnitine transport http://purl.obolibrary.org/obo/GO_1900749 GO:0046670 biolink:BiologicalProcess positive regulation of retinal cell programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina. go-plus.json positive regulation of retinal programmed cell death|up regulation of retinal programmed cell death|activation of retinal programmed cell death|stimulation of retinal programmed cell death|up-regulation of retinal programmed cell death|upregulation of retinal programmed cell death http://purl.obolibrary.org/obo/GO_0046670 GO:1900748 biolink:BiologicalProcess positive regulation of vascular endothelial growth factor signaling pathway Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway. go-plus.json up-regulation of vascular endothelial growth factor signalling pathway|positive regulation of VEGF-activated signaling pathway|up regulation of VEGF-activated signaling pathway|up-regulation of VEGF signaling|up regulation of vascular endothelial growth factor signaling pathway|upregulation of vascular endothelial growth factor signalling pathway|activation of VEGF signaling|upregulation of VEGF-activated signaling pathway|upregulation of vascular endothelial growth factor signaling pathway|positive regulation of VEGF signaling|up regulation of vascular endothelial growth factor signalling pathway|up regulation of VEGF signaling|positive regulation of vascular endothelial growth factor signalling pathway|up-regulation of VEGF-activated signaling pathway|up-regulation of vascular endothelial growth factor signaling pathway|activation of vascular endothelial growth factor signalling pathway|activation of vascular endothelial growth factor signaling pathway|upregulation of VEGF signaling|activation of VEGF-activated signaling pathway http://purl.obolibrary.org/obo/GO_1900748 CHEBI:45230 biolink:ChemicalSubstance (R)-dihydrolipoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45230 CHEBI:21285 biolink:ChemicalSubstance erythro-4-hydroxy-L-glutamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21285 CHEBI:21288 biolink:ChemicalSubstance L-erythrose go-plus.json http://purl.obolibrary.org/obo/CHEBI_21288 chebi_ph7_3 CHEBI:176338 biolink:ChemicalSubstance 2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosaminyl 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176338 GO:1900745 biolink:BiologicalProcess positive regulation of p38MAPK cascade Any process that activates or increases the frequency, rate or extent of p38MAPK cascade. go-plus.json up-regulation of p38MAPK cascade|up-regulation of p38 MAPK cascade|up regulation of p38 cascade|positive regulation of p38 cascade|activation of p38 MAPK cascade|activation of p38 cascade|upregulation of p38MAPK cascade|positive regulation of p38 MAPK cascade|up regulation of p38 MAPK cascade|up-regulation of p38 cascade|up regulation of p38MAPK cascade|activation of p38MAPK cascade|upregulation of p38 MAPK cascade|upregulation of p38 cascade http://purl.obolibrary.org/obo/GO_1900745 GO:1900744 biolink:BiologicalProcess regulation of p38MAPK cascade Any process that modulates the frequency, rate or extent of p38MAPK cascade. go-plus.json regulation of p38 MAPK cascade|regulation of p38 cascade http://purl.obolibrary.org/obo/GO_1900744 GO:1900747 biolink:BiologicalProcess negative regulation of vascular endothelial growth factor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway. go-plus.json down-regulation of VEGF-activated signaling pathway|negative regulation of VEGF-activated signaling pathway|inhibition of VEGF signaling|down-regulation of vascular endothelial growth factor signaling pathway|inhibition of vascular endothelial growth factor signalling pathway|downregulation of VEGF-activated signaling pathway|downregulation of vascular endothelial growth factor signaling pathway|down regulation of VEGF-activated signaling pathway|down regulation of vascular endothelial growth factor signalling pathway|down-regulation of VEGF signaling|negative regulation of VEGF signaling|down regulation of vascular endothelial growth factor signaling pathway|inhibition of vascular endothelial growth factor signaling pathway|downregulation of vascular endothelial growth factor signalling pathway|inhibition of VEGF-activated signaling pathway|downregulation of VEGF signaling|down-regulation of vascular endothelial growth factor signalling pathway|negative regulation of vascular endothelial growth factor signalling pathway|down regulation of VEGF signaling http://purl.obolibrary.org/obo/GO_1900747 GO:1900746 biolink:BiologicalProcess regulation of vascular endothelial growth factor signaling pathway Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway. go-plus.json regulation of VEGF-activated signaling pathway|regulation of vascular endothelial growth factor signalling pathway|regulation of VEGF signaling http://purl.obolibrary.org/obo/GO_1900746 GO:1900741 biolink:BiologicalProcess regulation of filamentous growth of a population of unicellular organisms in response to pH Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH. go-plus.json http://purl.obolibrary.org/obo/GO_1900741 GO:0046679 biolink:BiologicalProcess response to streptomycin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. go-plus.json streptomycin susceptibility/resistance http://purl.obolibrary.org/obo/GO_0046679 GO:1900740 biolink:BiologicalProcess positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway. go-plus.json upregulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up regulation of protein insertion into mitochondrial membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|positive regulation of protein insertion into mitochondrial membrane during induction of apoptosis|activation of protein insertion into mitochondrial membrane during induction of apoptosis|up regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|activation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|upregulation of protein insertion into mitochondrion membrane during induction of apoptosis|upregulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up-regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane during induction of apoptosis|activation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|upregulation of protein insertion into mitochondrial membrane during induction of apoptosis|positive regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|activation of protein insertion into mitochondrial membrane involved in induction of apoptosis|activation of protein insertion into mitochondrion membrane during induction of apoptosis http://purl.obolibrary.org/obo/GO_1900740 GO:0046678 biolink:BiologicalProcess response to bacteriocin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation. go-plus.json bacteriocin susceptibility/resistance http://purl.obolibrary.org/obo/GO_0046678 GO:1900743 biolink:BiologicalProcess positive regulation of filamentous growth of a population of unicellular organisms in response to pH Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH. go-plus.json up regulation of filamentous growth of a population of unicellular organisms in response to pH|activation of filamentous growth of a population of unicellular organisms in response to pH|up-regulation of filamentous growth of a population of unicellular organisms in response to pH|upregulation of filamentous growth of a population of unicellular organisms in response to pH http://purl.obolibrary.org/obo/GO_1900743 GO:0046677 biolink:BiologicalProcess response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. go-plus.json antibiotic susceptibility/resistance http://purl.obolibrary.org/obo/GO_0046677 goslim_chembl GO:1900742 biolink:BiologicalProcess negative regulation of filamentous growth of a population of unicellular organisms in response to pH Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH. go-plus.json downregulation of filamentous growth of a population of unicellular organisms in response to pH|down-regulation of filamentous growth of a population of unicellular organisms in response to pH|inhibition of filamentous growth of a population of unicellular organisms in response to pH|down regulation of filamentous growth of a population of unicellular organisms in response to pH http://purl.obolibrary.org/obo/GO_1900742 GO:0046676 biolink:BiologicalProcess negative regulation of insulin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. go-plus.json down regulation of insulin secretion|downregulation of insulin secretion|down-regulation of insulin secretion|inhibition of insulin secretion http://purl.obolibrary.org/obo/GO_0046676 GO:0046675 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046675 CHEBI:21282 biolink:ChemicalSubstance (3S,5S)-3,5-diaminohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21282 GO:0046674 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046674 GO:0046673 biolink:BiologicalProcess negative regulation of compound eye retinal cell programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. go-plus.json negative regulation of retina cell programmed cell death|downregulation of retinal cell programmed cell death|down regulation of retinal cell programmed cell death|inhibition of retinal cell programmed cell death|negative regulation of retinal cell programmed cell death|down-regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046673 GO:0046672 biolink:BiologicalProcess positive regulation of compound eye retinal cell programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. go-plus.json positive regulation of retinal cell programmed cell death|up regulation of retinal cell programmed cell death|upregulation of retinal cell programmed cell death|up-regulation of retinal cell programmed cell death|stimulation of retinal cell programmed cell death|activation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046672 CHEBI:59872 biolink:ChemicalSubstance heptaketide go-plus.json http://purl.obolibrary.org/obo/CHEBI_59872 CHEBI:59871 biolink:ChemicalSubstance D-alpha-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59871 chebi_ph7_3 GO:0071619 biolink:BiologicalProcess phosphorylation of RNA polymerase II C-terminal domain serine 2 residues The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans. go-plus.json http://purl.obolibrary.org/obo/GO_0071619 GO:0071618 biolink:MolecularActivity lysophosphatidylethanolamine acyltransferase activity Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine. go-plus.json http://purl.obolibrary.org/obo/GO_0071618 GO:0071617 biolink:MolecularActivity lysophospholipid acyltransferase activity Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid. go-plus.json http://purl.obolibrary.org/obo/GO_0071617 GO:0071616 biolink:BiologicalProcess acyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group. go-plus.json acyl-CoA anabolism|acyl-CoA synthesis|acyl-CoA biosynthesis|acyl-CoA formation http://purl.obolibrary.org/obo/GO_0071616 GO:0071615 biolink:BiologicalProcess obsolete oxidative deethylation OBSOLETE. The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate. go-plus.json http://purl.obolibrary.org/obo/GO_0071615 GO:0071614 biolink:MolecularActivity linoleic acid epoxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid. go-plus.json linoleic acid monooxygenase activity http://purl.obolibrary.org/obo/GO_0071614 GO:0071613 biolink:BiologicalProcess granzyme B production The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json http://purl.obolibrary.org/obo/GO_0071613 gocheck_do_not_annotate GO:0071612 biolink:BiologicalProcess IP-10 production The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CXCL10 production|chemokine (C-C motif) ligand 10 production http://purl.obolibrary.org/obo/GO_0071612 gocheck_do_not_annotate CHEBI:59879 biolink:ChemicalSubstance (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59879 chebi_ph7_3 GO:0071611 biolink:BiologicalProcess granulocyte colony-stimulating factor production The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json pluripoietin production|G-CSF production|filgrastim production|granulocyte colony stimulating factor production|CSF3 production|colony stimulating factor 3 (granulocyte) production|lenograstim production http://purl.obolibrary.org/obo/GO_0071611 gocheck_do_not_annotate GO:0071610 biolink:BiologicalProcess chemokine (C-C motif) ligand 1 production The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TCA-3 production|T cell activation 3 production|CCL1 production http://purl.obolibrary.org/obo/GO_0071610 gocheck_do_not_annotate CHEBI:59876 biolink:ChemicalSubstance N-acyl-D-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59876 chebi_ph7_3 CHEBI:59874 biolink:ChemicalSubstance N-acyl-L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59874 chebi_ph7_3 GO:0032039 biolink:CellularComponent integrator complex A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. go-plus.json http://purl.obolibrary.org/obo/GO_0032039 CHEBI:84824 biolink:ChemicalSubstance aromatic L-alpha-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84824 chebi_ph7_3 CHEBI:84822 biolink:ChemicalSubstance 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84822 chebi_ph7_3 GO:0007079 biolink:BiologicalProcess mitotic chromosome movement towards spindle pole The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis. go-plus.json mitotic chromosome movement to spindle pole|mitotic chromosome movement|sister chromosome movement towards spindle pole during mitosis|chromosome migration to spindle pole during mitosis|chromosome movement towards spindle pole during mitosis|mitotic sister chromosome movement towards spindle pole http://purl.obolibrary.org/obo/GO_0007079 GO:0007078 biolink:BiologicalProcess lamin depolymerization The cell cycle process in which lamin is depolymerized. go-plus.json http://purl.obolibrary.org/obo/GO_0007078 GO:0007077 biolink:BiologicalProcess mitotic nuclear membrane disassembly The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis. go-plus.json mitotic nuclear envelope catabolism|mitotic nuclear envelope breakdown|mitotic nuclear envelope degradation|local NEB|mitotic nuclear envelope disassembly|NEB|nuclear envelope breakdown http://purl.obolibrary.org/obo/GO_0007077 GO:0007076 biolink:BiologicalProcess mitotic chromosome condensation The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. go-plus.json http://purl.obolibrary.org/obo/GO_0007076 GO:0007075 biolink:BiologicalProcess positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. go-plus.json activation of transcription on exit from mitosis, from RNA polymerase III promoter|activation of transcription on exit from mitosis, from Pol III promoter http://purl.obolibrary.org/obo/GO_0007075 GO:0032030 biolink:MolecularActivity myosin I light chain binding Binding to a light chain of a myosin I complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032030 GO:0007085 biolink:BiologicalProcess obsolete nuclear membrane vesicle binding to chromatin OBSOLETE. (Was not defined before being made obsolete). go-plus.json nuclear membrane vesicle binding to chromatin http://purl.obolibrary.org/obo/GO_0007085 GO:0007084 biolink:BiologicalProcess mitotic nuclear membrane reassembly The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge. go-plus.json mitotic nuclear envelope reassembly|nuclear envelope repair|nuclear envelope resealing http://purl.obolibrary.org/obo/GO_0007084 CHEBI:60860 biolink:ChemicalSubstance 6-ammonio-5-oxocyclohex-2-ene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60860 chebi_ph7_3 CHEBI:60863 biolink:ChemicalSubstance (1S,6R)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60863 chebi_ph7_3 GO:0007083 biolink:BiologicalProcess mitotic chromosome decondensation The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells. go-plus.json http://purl.obolibrary.org/obo/GO_0007083 CHEBI:60862 biolink:ChemicalSubstance (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60862 chebi_ph7_3 GO:0007082 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007082 GO:0007081 biolink:BiologicalProcess obsolete mitotic sister-chromatid adhesion release OBSOLETE. (Was not defined before being made obsolete). go-plus.json mitotic sister-chromatid adhesion release http://purl.obolibrary.org/obo/GO_0007081 UBERON:8400021 biolink:AnatomicalEntity liver serosa Hepatic serous coat; peritoneal covering of the liver, enclosing almost all except for a triangular area on its posterior surface (the "bare area of the liver") and a smaller area where the liver and gallbladder are in direct contact. go-plus.json tunica serosa hepatis|serosa of liver http://purl.obolibrary.org/obo/UBERON_8400021 GO:0007080 biolink:BiologicalProcess mitotic metaphase plate congression The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis. go-plus.json http://purl.obolibrary.org/obo/GO_0007080 UBERON:8400023 biolink:AnatomicalEntity liver subserosa Subserosal tissue of liver. A zone of areolar connective tissue lying beneath the serous coat of the liver and distinguished with difficulty from the fibrous capsule of Glisson. go-plus.json tela subserosa hepatis|tela subserosa (hepar)|subserosal tissue of liver|subserous layer of liver|hepatic subserosa http://purl.obolibrary.org/obo/UBERON_8400023 GO:0032038 biolink:MolecularActivity myosin II heavy chain binding Binding to a heavy chain of a myosin II complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032038 CHEBI:60869 biolink:ChemicalSubstance (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60869 GO:0032037 biolink:MolecularActivity myosin I heavy chain binding Binding to a heavy chain of a myosin I complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032037 GO:0032036 biolink:MolecularActivity myosin heavy chain binding Binding to a heavy chain of a myosin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032036 GO:0032035 biolink:MolecularActivity myosin II tail binding Binding to the tail region of a myosin II heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032035 GO:0032034 biolink:MolecularActivity myosin II head/neck binding Binding to the head/neck region of a myosin II heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032034 GO:0032033 biolink:MolecularActivity myosin II light chain binding Binding to a light chain of a myosin II complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032033 GO:0032032 biolink:MolecularActivity myosin I tail binding Binding to the tail region of a myosin I heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032032 GO:0032031 biolink:MolecularActivity myosin I head/neck binding Binding to the head/neck region of a myosin I heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032031 SO:0001089 biolink:SequenceFeature post_translationally_modified_region A region where a transformation occurs in a protein after it has been synthesized. This which may regulate, stabilize, crosslink or introduce new chemical functionalities in the protein. http://en.wikipedia.org/wiki/Post_translational_modification go-plus.json post_translational_modification|modified residue|mod_res http://purl.obolibrary.org/obo/SO_0001089 biosapiens CHEBI:84839 biolink:ChemicalSubstance 1,2-di-[(9Z)-octadecenoyl]-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84839 GO:0032029 biolink:MolecularActivity myosin tail binding Binding to the tail region of a myosin heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032029 CHEBI:84838 biolink:ChemicalSubstance O-isobutyryl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84838 chebi_ph7_3 GO:0032028 biolink:MolecularActivity myosin head/neck binding Binding to the head/neck region of a myosin heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032028 CHEBI:84836 biolink:ChemicalSubstance 1,2-di-octadecenoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84836 chebi_ph7_3 CHEBI:84834 biolink:ChemicalSubstance O-hexanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84834 chebi_ph7_3 GO:0007089 biolink:BiologicalProcess traversing start control point of mitotic cell cycle A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity. go-plus.json http://purl.obolibrary.org/obo/GO_0007089 GO:0007088 biolink:BiologicalProcess regulation of mitotic nuclear division Any process that modulates the frequency, rate or extent of mitosis. go-plus.json regulation of mitosis http://purl.obolibrary.org/obo/GO_0007088 GO:0007087 biolink:BiologicalProcess mitotic nuclear pore complex reassembly The cell cycle process in which nuclear pore complexes reform during mitotic cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0007087 CHEBI:60870 biolink:ChemicalSubstance aza fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60870 GO:0007086 biolink:BiologicalProcess vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly. go-plus.json http://purl.obolibrary.org/obo/GO_0007086 GO:0007096 biolink:BiologicalProcess regulation of exit from mitosis Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity. go-plus.json http://purl.obolibrary.org/obo/GO_0007096 GO:0007095 biolink:BiologicalProcess mitotic G2 DNA damage checkpoint signaling A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. go-plus.json signal transduction involved in G2/M transition DNA damage checkpoint|inhibition of signal transduction involved in mitotic G2 DNA damage checkpoint|signal transduction involved in mitotic G2 DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|mitotic cell cycle G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|signal transduction involved in mitotic G2/M transition DNA damage checkpoint|signal transduction involved in G2 DNA damage checkpoint|mitotic G2 DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|negative regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|G2 DNA damage checkpoint|negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint http://purl.obolibrary.org/obo/GO_0007095 GO:0007094 biolink:BiologicalProcess mitotic spindle assembly checkpoint signaling A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint, that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. go-plus.json mitotic checkpoint|signaling cascade involved in SAC-independent checkpoint|signaling pathway involved in SAC-independent checkpoint|signalling pathway involved in Dma1-dependent checkpoint|mitotic spindle assembly checkpoint signaling|mitotic cell cycle spindle assembly checkpoint|signalling cascade involved in SAC-independent checkpoint|signalling pathway involved in SAC-independent checkpoint|SAC-independent checkpoint|signaling pathway involved in Dma1-dependent checkpoint|mitotic spindle assembly checkpoint signalling|signal transduction involved in SAC-independent checkpoint|signal transduction involved in mitotic spindle assembly checkpoint|signalling cascade involved in Dma1-dependent checkpoint|Dma1-dependent checkpoint|signaling cascade involved in Dma1-dependent checkpoint|signal transduction involved in mitotic cell cycle spindle assembly checkpoint|Mad2-dependent checkpoint|signal transduction involved in Dma1-dependent checkpoint|mitotic spindle assembly checkpoint http://purl.obolibrary.org/obo/GO_0007094 CHEBI:60874 biolink:ChemicalSubstance phenylacetylglycine(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60874 chebi_ph7_3 GO:0007093 biolink:BiologicalProcess mitotic cell cycle checkpoint signaling A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage. go-plus.json mitotic checkpoint|signal transduction involved in mitotic cell cycle checkpoint|signal transduction involved in mitotic cell cycle G1/S checkpoint|signal transduction involved in mitotic G2/M transition checkpoint|mitotic cell cycle checkpoint http://purl.obolibrary.org/obo/GO_0007093 gocheck_do_not_annotate CHEBI:60873 biolink:ChemicalSubstance 2',3'-cyclic UMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60873 chebi_ph7_3 GO:0007092 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007092 GO:0007091 biolink:BiologicalProcess metaphase/anaphase transition of mitotic cell cycle The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. go-plus.json mitotic metaphase/anaphase transition|metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process http://purl.obolibrary.org/obo/GO_0007091 CHEBI:60875 biolink:ChemicalSubstance 3'-CMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60875 chebi_ph7_3 GO:0007090 biolink:BiologicalProcess obsolete regulation of S phase of mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle. go-plus.json regulation of S-phase of mitotic cell cycle|regulation of S phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0007090 CHEBI:60878 biolink:ChemicalSubstance 3-geranyl-4-hydroxybenzoate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60878 chebi_ph7_3 CHEBI:60877 biolink:ChemicalSubstance 2',3'-cyclic CMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60877 chebi_ph7_3 GO:0032027 biolink:MolecularActivity myosin light chain binding Binding to a light chain of a myosin complex. go-plus.json http://purl.obolibrary.org/obo/GO_0032027 GO:0032026 biolink:BiologicalProcess response to magnesium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032026 CHEBI:60879 biolink:ChemicalSubstance 2',3'-cyclic AMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60879 chebi_ph7_3 GO:0032025 biolink:BiologicalProcess response to cobalt ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032025 GO:0032024 biolink:BiologicalProcess positive regulation of insulin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. go-plus.json upregulation of insulin secretion|up regulation of insulin secretion|activation of insulin secretion|stimulation of insulin secretion|up-regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0032024 GO:0032023 biolink:BiologicalProcess trypsinogen activation The proteolytic processing of trypsinogen to the active form, trypsin. go-plus.json cleavage of trypsinogen to trypsin http://purl.obolibrary.org/obo/GO_0032023 GO:0032022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032022 GO:0032021 biolink:CellularComponent NELF complex A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing. go-plus.json negative elongation factor complex http://purl.obolibrary.org/obo/GO_0032021 GO:0032020 biolink:BiologicalProcess ISG15-protein conjugation The covalent addition to a protein of ISG15, a ubiquitin-like protein. go-plus.json http://purl.obolibrary.org/obo/GO_0032020 CHEBI:11909 biolink:ChemicalSubstance 3beta-hydroxy-5alpha-pregnan-20-one go-plus.json http://purl.obolibrary.org/obo/CHEBI_11909 chebi_ph7_3 GO:0032019 biolink:CellularComponent mitochondrial cloud A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material. go-plus.json mitochondrial aggregate|Balbiani body http://purl.obolibrary.org/obo/GO_0032019 GO:0032018 biolink:MolecularActivity 2-methylbutanol:NADP oxidoreductase activity Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+. go-plus.json 2-methylbutanal reductase (NADP) activity|2-methylbutyraldehyde reductase (NADP) activity http://purl.obolibrary.org/obo/GO_0032018 GO:0032017 biolink:BiologicalProcess positive regulation of Ran protein signal transduction Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction. go-plus.json up regulation of Ran protein signal transduction|activation of Ran protein signal transduction|stimulation of Ran protein signal transduction|up-regulation of Ran protein signal transduction|upregulation of Ran protein signal transduction http://purl.obolibrary.org/obo/GO_0032017 CHEBI:84847 biolink:ChemicalSubstance 2,6-dimethylheptanoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84847 chebi_ph7_3 CHEBI:11901 biolink:ChemicalSubstance 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11901 chebi_ph7_3 GO:0007059 biolink:BiologicalProcess chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. Wikipedia:Chromosome_segregation go-plus.json chromosome division|chromosome transmission http://purl.obolibrary.org/obo/GO_0007059 goslim_chembl|goslim_yeast|goslim_pir|goslim_generic GO:0007058 biolink:BiologicalProcess spindle assembly involved in female meiosis II The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. go-plus.json female meiosis II spindle assembly http://purl.obolibrary.org/obo/GO_0007058 GO:0007057 biolink:BiologicalProcess spindle assembly involved in female meiosis I The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. go-plus.json female meiosis I spindle assembly http://purl.obolibrary.org/obo/GO_0007057 CHEBI:84843 biolink:ChemicalSubstance (R)-2,6-dimethylheptanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84843 chebi_ph7_3 GO:0007056 biolink:BiologicalProcess spindle assembly involved in female meiosis The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. go-plus.json female meiotic spindle assembly http://purl.obolibrary.org/obo/GO_0007056 CHEBI:84842 biolink:ChemicalSubstance (R)-3-hydroxybutyrylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84842 chebi_ph7_3 GO:0007055 biolink:BiologicalProcess spindle assembly involved in male meiosis II The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. go-plus.json male meiosis II spindle assembly http://purl.obolibrary.org/obo/GO_0007055 GO:0007054 biolink:BiologicalProcess spindle assembly involved in male meiosis I The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. go-plus.json male meiosis I spindle assembly http://purl.obolibrary.org/obo/GO_0007054 CHEBI:84841 biolink:ChemicalSubstance (R)-acetoacetylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84841 chebi_ph7_3 CHEBI:84840 biolink:ChemicalSubstance (R)-2-methylbutyrylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84840 chebi_ph7_3 GO:0007053 biolink:BiologicalProcess spindle assembly involved in male meiosis The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007053 CHEBI:60880 biolink:ChemicalSubstance 3'-AMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60880 chebi_ph7_3 GO:0007063 biolink:BiologicalProcess regulation of sister chromatid cohesion Any process that modulates the frequency, rate or extent of sister chromatid cohesion. go-plus.json http://purl.obolibrary.org/obo/GO_0007063 GO:0007062 biolink:BiologicalProcess sister chromatid cohesion The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other. go-plus.json sister chromatid alignment|coheson-mediated DNA tethering http://purl.obolibrary.org/obo/GO_0007062 CHEBI:60885 biolink:ChemicalSubstance (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60885 chebi_ph7_3 GO:0007061 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007061 GO:0007060 biolink:BiologicalProcess male meiosis chromosome segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male. go-plus.json http://purl.obolibrary.org/obo/GO_0007060 CHEBI:60887 biolink:ChemicalSubstance 3-hydroxy-D-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60887 CHEBI:60886 biolink:ChemicalSubstance (2E)-2-hydroxypenta-2,4-dienoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60886 chebi_ph7_3 GO:0032016 biolink:BiologicalProcess negative regulation of Ran protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction. go-plus.json down regulation of Ran protein signal transduction|downregulation of Ran protein signal transduction|down-regulation of Ran protein signal transduction|inhibition of Ran protein signal transduction http://purl.obolibrary.org/obo/GO_0032016 GO:0032015 biolink:BiologicalProcess regulation of Ran protein signal transduction Any process that modulates the frequency, rate or extent of Ran protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0032015 GO:0032014 biolink:BiologicalProcess positive regulation of ARF protein signal transduction Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction. go-plus.json upregulation of ARF protein signal transduction|up regulation of ARF protein signal transduction|activation of ARF protein signal transduction|stimulation of ARF protein signal transduction|up-regulation of ARF protein signal transduction http://purl.obolibrary.org/obo/GO_0032014 GO:0032013 biolink:BiologicalProcess negative regulation of ARF protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction. go-plus.json down regulation of ARF protein signal transduction|downregulation of ARF protein signal transduction|down-regulation of ARF protein signal transduction|inhibition of ARF protein signal transduction http://purl.obolibrary.org/obo/GO_0032013 GO:0032012 biolink:BiologicalProcess regulation of ARF protein signal transduction Any process that modulates the frequency, rate or extent of ARF protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0032012 GO:0032011 biolink:BiologicalProcess ARF protein signal transduction A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state. go-plus.json http://purl.obolibrary.org/obo/GO_0032011 GO:0032010 biolink:CellularComponent phagolysosome A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes. Wikipedia:Phagolysosome go-plus.json late phagocytic vesicle|late phagosome http://purl.obolibrary.org/obo/GO_0032010 GO:0032009 biolink:CellularComponent early phagosome A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis. go-plus.json early phagocytic vesicle http://purl.obolibrary.org/obo/GO_0032009 GO:0032008 biolink:BiologicalProcess positive regulation of TOR signaling Any process that activates or increases the frequency, rate or extent of TOR signaling. go-plus.json up-regulation of TOR signaling pathway|upregulation of TOR signaling pathway|positive regulation of target of rapamycin signaling pathway|positive regulation of TOR signalling pathway|up regulation of TOR signaling pathway|positive regulation of TOR signaling pathway|activation of TOR signaling pathway|positive regulation of target of rapamycin signalling pathway|stimulation of TOR signaling pathway|positive regulation of TOR signaling cascade http://purl.obolibrary.org/obo/GO_0032008 GO:0032007 biolink:BiologicalProcess negative regulation of TOR signaling Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling. go-plus.json negative regulation of TOR signaling cascade|inhibition of TOR signaling pathway|negative regulation of TOR signalling pathway|down regulation of TOR signaling pathway|negative regulation of target of rapamycin signaling pathway|downregulation of TOR signaling pathway|negative regulation of target of rapamycin signalling pathway|down-regulation of TOR signaling pathway|negative regulation of TOR signaling pathway http://purl.obolibrary.org/obo/GO_0032007 GO:0032006 biolink:BiologicalProcess regulation of TOR signaling Any process that modulates the frequency, rate or extent of TOR signaling. go-plus.json regulation of target of rapamycin signaling pathway|regulation of TOR signaling pathway|regulation of TOR signalling pathway|regulation of TOR signaling cascade|regulation of target of rapamycin signalling pathway http://purl.obolibrary.org/obo/GO_0032006 GO:0007069 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle. go-plus.json down-regulation of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from RNA polymerase I promoter, mitotic|inhibition of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from Pol I promoter during mitosis|mitotic repression of transcription from Pol I promoter|down regulation of transcription from RNA polymerase I promoter during mitosis|downregulation of transcription from RNA polymerase I promoter during mitosis http://purl.obolibrary.org/obo/GO_0007069 GO:0007068 biolink:BiologicalProcess obsolete negative regulation of transcription during mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle. go-plus.json mitotic repression of transcription|downregulation of transcription during mitosis|down regulation of transcription during mitosis|inhibition of transcription during mitosis|down-regulation of transcription during mitosis|negative regulation of transcription, mitotic http://purl.obolibrary.org/obo/GO_0007068 GO:0007067 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007067 CHEBI:84854 biolink:ChemicalSubstance 2-hydroxyheptadecanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84854 GO:0007066 biolink:BiologicalProcess female meiosis sister chromatid cohesion The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female. go-plus.json http://purl.obolibrary.org/obo/GO_0007066 GO:0007065 biolink:BiologicalProcess male meiosis sister chromatid cohesion The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male. go-plus.json http://purl.obolibrary.org/obo/GO_0007065 CHEBI:60892 biolink:ChemicalSubstance polyamino carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60892 GO:0007064 biolink:BiologicalProcess mitotic sister chromatid cohesion The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission. go-plus.json http://purl.obolibrary.org/obo/GO_0007064 CHEBI:60894 biolink:ChemicalSubstance (3S)-3-hydroxy-D-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60894 chebi_ph7_3 CHEBI:84850 biolink:ChemicalSubstance L-selenohomocysteine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84850 chebi_ph7_3 GO:0007074 biolink:BiologicalProcess positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. go-plus.json activation of transcription on exit from mitosis, from Pol II promoter|activation of transcription on exit from mitosis, from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_0007074 GO:0007073 biolink:BiologicalProcess positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. go-plus.json activation of transcription on exit from mitosis, from Pol I promoter|activation of transcription on exit from mitosis, from RNA polymerase I promoter http://purl.obolibrary.org/obo/GO_0007073 CHEBI:60893 biolink:ChemicalSubstance (3S)-3-hydroxy-D-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60893 GO:0007072 biolink:BiologicalProcess positive regulation of transcription involved in exit from mitosis Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. go-plus.json activation of transcription on exit from mitosis http://purl.obolibrary.org/obo/GO_0007072 GO:0007071 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle. go-plus.json down regulation of transcription from RNA polymerase III promoter during mitosis|downregulation of transcription from RNA polymerase III promoter during mitosis|down-regulation of transcription from RNA polymerase III promoter during mitosis|negative regulation of transcription from RNA polymerase III promoter, mitotic|inhibition of transcription from RNA polymerase III promoter during mitosis|negative regulation of transcription from Pol III promoter during mitosis|mitotic repression of transcription from Pol III promoter http://purl.obolibrary.org/obo/GO_0007071 CHEBI:60895 biolink:ChemicalSubstance D-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60895 GO:0007070 biolink:BiologicalProcess obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle. go-plus.json negative regulation of transcription from Pol II promoter during mitosis|down-regulation of transcription from RNA polymerase II promoter during mitosis|negative regulation of transcription from RNA polymerase II promoter, mitotic|mitotic repression of transcription from Pol II promoter|downregulation of transcription from RNA polymerase II promoter during mitosis|down regulation of transcription from RNA polymerase II promoter during mitosis|inhibition of transcription from RNA polymerase II promoter during mitosis http://purl.obolibrary.org/obo/GO_0007070 CHEBI:60898 biolink:ChemicalSubstance (3R)-3-hydroxy-D-aspartate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60898 chebi_ph7_3 CHEBI:60897 biolink:ChemicalSubstance (3R)-3-hydroxy-D-aspartic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60897 CHEBI:60899 biolink:ChemicalSubstance ubiquinol-0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_60899 chebi_ph7_3 GO:0032005 biolink:BiologicalProcess signal transduction involved in positive regulation of conjugation with cellular fusion The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. go-plus.json http://purl.obolibrary.org/obo/GO_0032005 GO:0032004 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032004 GO:0032003 biolink:MolecularActivity interleukin-28 receptor binding Binding to an interleukin-28 receptor. go-plus.json IL-28|interleukin-28 receptor ligand http://purl.obolibrary.org/obo/GO_0032003 GO:0032002 biolink:CellularComponent interleukin-28 receptor complex A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1). go-plus.json IL-28 receptor complex http://purl.obolibrary.org/obo/GO_0032002 GO:0032001 biolink:MolecularActivity 1,4-alpha-glucan 6-alpha-glucosyltransferase activity Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan. EC:2.4.1.24|MetaCyc:2.4.1.24-RXN go-plus.json 1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity|D-glucosyltransferase|oligoglucan-branching glycosyltransferase activity|T-enzyme http://purl.obolibrary.org/obo/GO_0032001 GO:0032000 biolink:BiologicalProcess positive regulation of fatty acid beta-oxidation Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation. go-plus.json up-regulation of fatty acid beta-oxidation|upregulation of fatty acid beta-oxidation|up regulation of fatty acid beta-oxidation|activation of fatty acid beta-oxidation|stimulation of fatty acid beta-oxidation http://purl.obolibrary.org/obo/GO_0032000 GO:0007039 biolink:BiologicalProcess protein catabolic process in the vacuole The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. go-plus.json vacuolar protein catabolism|vacuolar protein degradation|vacuolar protein breakdown|vacuolar protein catabolic process http://purl.obolibrary.org/obo/GO_0007039 GO:0007038 biolink:BiologicalProcess endocytosed protein transport to vacuole The directed movement of proteins imported into a cell by endocytosis to the vacuole. go-plus.json delivery of endocytosed proteins to the vacuole http://purl.obolibrary.org/obo/GO_0007038 GO:0007037 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007037 GO:0007036 biolink:BiologicalProcess vacuolar calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings. go-plus.json http://purl.obolibrary.org/obo/GO_0007036 CHEBI:84866 biolink:ChemicalSubstance (2S)-methylsuccinyl-CoA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84866 chebi_ph7_3 GO:0007035 biolink:BiologicalProcess vacuolar acidification Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion. go-plus.json http://purl.obolibrary.org/obo/GO_0007035 GO:0007034 biolink:BiologicalProcess vacuolar transport The directed movement of substances into, out of or within a vacuole. go-plus.json http://purl.obolibrary.org/obo/GO_0007034 goslim_generic|goslim_chembl GO:0007033 biolink:BiologicalProcess vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. go-plus.json vacuolar assembly|vacuole organization and biogenesis|vacuole organisation|vacuole biogenesis http://purl.obolibrary.org/obo/GO_0007033 goslim_yeast|goslim_pir GO:0007032 biolink:BiologicalProcess endosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. go-plus.json endosome organization and biogenesis|endosome organisation http://purl.obolibrary.org/obo/GO_0007032 goslim_pir GO:0007031 biolink:BiologicalProcess peroxisome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. go-plus.json peroxisome-assembly ATPase activity|peroxisome organization and biogenesis|peroxisome organisation http://purl.obolibrary.org/obo/GO_0007031 goslim_pombe|goslim_yeast|goslim_pir GO:0007041 biolink:BiologicalProcess lysosomal transport The directed movement of substances into, out of or within a lysosome. go-plus.json http://purl.obolibrary.org/obo/GO_0007041 GO:0007040 biolink:BiologicalProcess lysosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. go-plus.json lysosome organisation|lysosome organization and biogenesis http://purl.obolibrary.org/obo/GO_0007040 CHEBI:166904 biolink:ChemicalSubstance glycosyldiradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_166904 CHEBI:166903 biolink:ChemicalSubstance glycosylmonoradylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_166903 CHEBI:166902 biolink:ChemicalSubstance noradrenaline(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_166902 CHEBI:70231 biolink:ChemicalSubstance phenazine-1,6-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_70231 GO:0007049 biolink:BiologicalProcess cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. Wikipedia:Cell_cycle go-plus.json cell-division cycle http://purl.obolibrary.org/obo/GO_0007049 goslim_candida|goslim_agr|gocheck_do_not_manually_annotate|goslim_pir|goslim_plant|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl GO:0007048 biolink:BiologicalProcess obsolete oncogenesis OBSOLETE. (Was not defined before being made obsolete). go-plus.json oncogenesis http://purl.obolibrary.org/obo/GO_0007048 CHEBI:84879 biolink:ChemicalSubstance nitroxyl go-plus.json http://purl.obolibrary.org/obo/CHEBI_84879 chebi_ph7_3 GO:0007047 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007047 GO:0007046 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007046 GO:0007045 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007045 GO:0007044 biolink:BiologicalProcess cell-substrate junction assembly The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. go-plus.json cell-substrate adherens junction assembly http://purl.obolibrary.org/obo/GO_0007044 GO:0007043 biolink:BiologicalProcess cell-cell junction assembly The aggregation, arrangement and bonding together of a set of components to form a junction between cells. go-plus.json intercellular junction assembly http://purl.obolibrary.org/obo/GO_0007043 GO:0007042 biolink:BiologicalProcess lysosomal lumen acidification Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. go-plus.json lysosome pH reduction http://purl.obolibrary.org/obo/GO_0007042 GO:0007052 biolink:BiologicalProcess mitotic spindle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. go-plus.json mitotic spindle organization and biogenesis in nucleus|mitotic spindle organisation in nucleus|spindle organization and biogenesis during mitosis|mitotic spindle stabilization|mitotic spindle organisation|spindle organization and biogenesis in nucleus during mitosis|mitotic spindle organization and biogenesis|mitotic spindle organization and biogenesis in cell nucleus|mitotic spindle organization in nucleus http://purl.obolibrary.org/obo/GO_0007052 GO:0007051 biolink:BiologicalProcess spindle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. go-plus.json spindle stabilization|spindle organization and biogenesis|spindle organisation http://purl.obolibrary.org/obo/GO_0007051 GO:0007050 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007050 GO:0007019 biolink:BiologicalProcess microtubule depolymerization The removal of tubulin heterodimers from one or both ends of a microtubule. go-plus.json microtubule depolymerization during nuclear congression|microtubule shortening|microtubule catastrophe|microtubule disassembly http://purl.obolibrary.org/obo/GO_0007019 GO:0007018 biolink:BiologicalProcess microtubule-based movement A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. go-plus.json http://purl.obolibrary.org/obo/GO_0007018 GO:0007017 biolink:BiologicalProcess microtubule-based process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0007017 goslim_chembl GO:0007016 biolink:BiologicalProcess obsolete cytoskeletal anchoring at plasma membrane OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane. go-plus.json cytoskeletal anchoring activity http://purl.obolibrary.org/obo/GO_0007016 GO:0007015 biolink:BiologicalProcess actin filament organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. go-plus.json actin filament organisation|regulation of actin filament localization http://purl.obolibrary.org/obo/GO_0007015 GO:0007014 biolink:BiologicalProcess actin ubiquitination The modification of actin by addition of ubiquitin groups. go-plus.json indirect flight muscle actin ubiquitination http://purl.obolibrary.org/obo/GO_0007014 GO:0007013 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007013 GO:0007012 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007012 GO:0007011 biolink:BiologicalProcess obsolete regulation of cytoskeleton OBSOLETE. Any process that modulates the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton. go-plus.json regulation of cytoskeleton http://purl.obolibrary.org/obo/GO_0007011 CHEBI:84886 biolink:ChemicalSubstance GDP-alpha-D-mannuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84886 chebi_ph7_3 GO:0007010 biolink:BiologicalProcess cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. go-plus.json cytoskeletal regulator activity|cytoskeleton organisation|cytoskeletal organization and biogenesis|cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0007010 goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_aspergillus CHEBI:84881 biolink:ChemicalSubstance GDP-D-mannose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84881 chebi_ph7_3 CHEBI:84880 biolink:ChemicalSubstance GDP-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_84880 GO:0007029 biolink:BiologicalProcess endoplasmic reticulum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. go-plus.json ER organisation|endoplasmic reticulum organisation|endoplasmic reticulum morphology|endoplasmic reticulum organization and biogenesis|ER organization and biogenesis http://purl.obolibrary.org/obo/GO_0007029 goslim_pir GO:0007028 biolink:BiologicalProcess cytoplasm organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. go-plus.json cytoplasm organisation|cytoplasm organization and biogenesis http://purl.obolibrary.org/obo/GO_0007028 goslim_pir GO:0007027 biolink:BiologicalProcess negative regulation of axonemal microtubule depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme. go-plus.json axonemal microtubule stabilization|negative regulation of microtubule depolymerization in axoneme http://purl.obolibrary.org/obo/GO_0007027 GO:0007026 biolink:BiologicalProcess negative regulation of microtubule depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. go-plus.json microtubule stabilization|negative regulation of microtubule disassembly|negative regulation of microtubule catastrophe|down-regulation of microtubule depolymerization|downregulation of microtubule depolymerization|down regulation of microtubule depolymerization|inhibition of microtubule depolymerization|microtubule rescue http://purl.obolibrary.org/obo/GO_0007026 UBERON:8400024 biolink:AnatomicalEntity subcapsular region of liver Region of liver parenchyma immediately below the capsule. This region is frequently specified in pathology diagnoses. go-plus.json liver subcapsular tissue|liver subcapsular region|subcapsular tissue of liver http://purl.obolibrary.org/obo/UBERON_8400024 GO:0007025 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007025 GO:0007024 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007024 CHEBI:84898 biolink:ChemicalSubstance (R)-crotonylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84898 chebi_ph7_3 GO:0007023 biolink:BiologicalProcess post-chaperonin tubulin folding pathway Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors. go-plus.json http://purl.obolibrary.org/obo/GO_0007023 GO:0007022 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007022 CHEBI:84897 biolink:ChemicalSubstance nogalonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84897 chebi_ph7_3 GO:0007021 biolink:BiologicalProcess tubulin complex assembly The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer. go-plus.json tubulin assembly|tubulin-specific chaperone activity|tubulin folding http://purl.obolibrary.org/obo/GO_0007021 GO:0007020 biolink:BiologicalProcess microtubule nucleation The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). Wikipedia:Microtubule_nucleation go-plus.json http://purl.obolibrary.org/obo/GO_0007020 GO:0007030 biolink:BiologicalProcess Golgi organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. go-plus.json Golgi organisation|Golgi organization and biogenesis http://purl.obolibrary.org/obo/GO_0007030 goslim_pir CHEBI:35816 biolink:ChemicalSubstance leprostatic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35816 CHEBI:35818 biolink:ChemicalSubstance coccidiostat go-plus.json http://purl.obolibrary.org/obo/CHEBI_35818 CHEBI:35819 biolink:ChemicalSubstance branched-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35819 CHEBI:35810 biolink:ChemicalSubstance 3-carboxy-3-hydroxypentanedioate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35810 CHEBI:35812 biolink:ChemicalSubstance oxfendazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35812 chebi_ph7_3 CHEBI:35811 biolink:ChemicalSubstance 2-endo-hydroxy-1,8-cineole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35811 chebi_ph7_3 GO:0071594 biolink:BiologicalProcess thymocyte aggregation The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules. go-plus.json immature T cell aggregation|thymic lymphocyte aggregation|immature T-lymphocyte aggregation|immature T-cell aggregation|T cell precursor aggregation http://purl.obolibrary.org/obo/GO_0071594 GO:0071593 biolink:BiologicalProcess lymphocyte aggregation The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0071593 GO:0071592 biolink:BiologicalProcess nicotinic acid riboside biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid. go-plus.json nicotinic acid riboside synthesis|nicotinic acid riboside formation|D-ribosylnicotinic acid biosynthetic process|nicotinic acid riboside biosynthesis|nicotinic acid riboside anabolism http://purl.obolibrary.org/obo/GO_0071592 GO:0071591 biolink:BiologicalProcess nicotinic acid riboside metabolic process The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid. go-plus.json nicotinic acid riboside metabolism|D-ribosylnicotinic acid metabolic process http://purl.obolibrary.org/obo/GO_0071591 GO:0071590 biolink:BiologicalProcess nicotinamide riboside biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. go-plus.json nicotinamide riboside biosynthesis|N-ribosylnicotinamide biosynthetic process|nicotinamide riboside anabolism|nicotinamide riboside synthesis|nicotinamide riboside formation http://purl.obolibrary.org/obo/GO_0071590 CHEBI:35825 biolink:ChemicalSubstance mandelic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35825 CHEBI:35821 biolink:ChemicalSubstance anticholesteremic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35821 CHEBI:35820 biolink:ChemicalSubstance antiprotozoal drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35820 GO:0071599 biolink:BiologicalProcess otic vesicle development The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. go-plus.json http://purl.obolibrary.org/obo/GO_0071599 GO:0071598 biolink:CellularComponent neuronal ribonucleoprotein granule A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli. go-plus.json neuronal RNA granule|neuronal RNP granule http://purl.obolibrary.org/obo/GO_0071598 GO:0071597 biolink:CellularComponent cellular birth scar Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation. go-plus.json http://purl.obolibrary.org/obo/GO_0071597 GO:0071596 biolink:BiologicalProcess ubiquitin-dependent protein catabolic process via the N-end rule pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. go-plus.json ubiquitin-dependent protein catabolism via the N-end rule pathway|ubiquitin-dependent protein degradation via the N-end rule pathway|ubiquitin-dependent protein breakdown via the N-end rule pathway http://purl.obolibrary.org/obo/GO_0071596 GO:0071595 biolink:CellularComponent Nem1-Spo7 phosphatase complex A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p. go-plus.json http://purl.obolibrary.org/obo/GO_0071595 CHEBI:11867 biolink:ChemicalSubstance 3-oxo-5beta-cholanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11867 chebi_ph7_3 CHEBI:60801 biolink:ChemicalSubstance guanyl deoxyribonucleotide residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60801 CHEBI:60807 biolink:ChemicalSubstance anaesthesia adjuvant go-plus.json http://purl.obolibrary.org/obo/CHEBI_60807 CHEBI:60809 biolink:ChemicalSubstance adjuvant go-plus.json http://purl.obolibrary.org/obo/CHEBI_60809 CHEBI:35802 biolink:ChemicalSubstance 3-carboxy-2-(carboxymethyl)-2-hydroxypropanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35802 CHEBI:35804 biolink:ChemicalSubstance citrate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35804 CHEBI:35806 biolink:ChemicalSubstance 3,4-dicarboxy-3-hydroxybutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35806 CHEBI:35809 biolink:ChemicalSubstance 2-(carboxymethyl)-2-hydroxysuccinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35809 CHEBI:35808 biolink:ChemicalSubstance citrate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35808 UBERON:0002294 biolink:AnatomicalEntity biliary system Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree). go-plus.json biliary tract|biliary apparatus http://purl.obolibrary.org/obo/UBERON_0002294 UBERON:0002296 biolink:AnatomicalEntity dorsal mesentery The mesentery that originates from the dorsal side of the peritoneal cavity[ZFA]. go-plus.json mesenterium dorsale commune|dorsal mesogastrium http://purl.obolibrary.org/obo/UBERON_0002296 UBERON:0002290 biolink:AnatomicalEntity choroid plexus of fourth ventricle Choroid plexus of the fourth ventricle go-plus.json 4th ventricle choroid plexus|fourth ventricle choroid plexus|fourth ventricle chorioid plexus of cerebral hemisphere|choroid plexus fourth ventricle|chorioid plexus of cerebral hemisphere of fourth ventricle|chorioid plexus of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002290 CHEBI:35801 biolink:ChemicalSubstance nitroso group go-plus.json http://purl.obolibrary.org/obo/CHEBI_35801 chebi_ph7_3 UBERON:0002291 biolink:AnatomicalEntity central canal of spinal cord Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. go-plus.json central canal, spinal cord/medulla|central canal|canalis centralis|spinal cord central canal|central canal of spinal cord|ventricle of spinal cord http://purl.obolibrary.org/obo/UBERON_0002291 CHEBI:35800 biolink:ChemicalSubstance nitroso compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35800 CHEBI:11851 biolink:ChemicalSubstance 3-methyl-2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11851 chebi_ph7_3 CHEBI:60816 biolink:ChemicalSubstance immunogen go-plus.json http://purl.obolibrary.org/obo/CHEBI_60816 CHEBI:60815 biolink:ChemicalSubstance lysobisphosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60815 UBERON:0002298 biolink:AnatomicalEntity brainstem Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. go-plus.json lamina pallidi incompleta|brain stem|lamina medullaris incompleta pallidi|truncus encephali|lamella pallidi incompleta|accessory medullary lamina of pallidum|lamina medullaris accessoria|truncus encephalicus http://purl.obolibrary.org/obo/UBERON_0002298 CHEBI:60818 biolink:ChemicalSubstance 2,2'-lysobisphosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60818 CHEBI:60817 biolink:ChemicalSubstance 1,1'-lysobisphosphatidic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60817 UBERON:0002299 biolink:AnatomicalEntity alveolus of lung Spherical outcropping of the respiratory bronchioles and primary site of gas exchange with the blood. Alveoli are particular to mammalian lungs. Different structures are involved in gas exchange in other vertebrates[WP]. go-plus.json alveolus pulmonis|lung alveolus|pulmonary alveolus|alveoli|respiratory alveolus|alveolus|alveolus pulmonis|respiratory alveoli http://purl.obolibrary.org/obo/UBERON_0002299 CHEBI:60819 biolink:ChemicalSubstance diphenyl phthalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60819 chebi_ph7_3 CHEBI:11807 biolink:ChemicalSubstance 5-hydroxy-6-methylpyridine-3,4-dicarboxylate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11807 CHEBI:11805 biolink:ChemicalSubstance 3-hydroxyisobutyrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11805 chebi_ph7_3 CHEBI:60821 biolink:ChemicalSubstance streptothricin F go-plus.json http://purl.obolibrary.org/obo/CHEBI_60821 CHEBI:60820 biolink:ChemicalSubstance 1-C-(indol-3-yl)glycerol 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60820 chebi_ph7_3 CHEBI:60823 biolink:ChemicalSubstance streptothricin F acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60823 CHEBI:60822 biolink:ChemicalSubstance streptothricin F(3+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60822 chebi_ph7_3 CHEBI:60826 biolink:ChemicalSubstance streptothricin acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60826 CHEBI:60829 biolink:ChemicalSubstance streptothricin D(5+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60829 chebi_ph7_3 CHEBI:60828 biolink:ChemicalSubstance streptothricin D go-plus.json http://purl.obolibrary.org/obo/CHEBI_60828 NCBITaxon:46877 biolink:OrganismalEntity Drosophilini go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_46877 CHEBI:60830 biolink:ChemicalSubstance streptothricin D acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60830 CHEBI:60832 biolink:ChemicalSubstance tubulin modulator go-plus.json http://purl.obolibrary.org/obo/CHEBI_60832 CHEBI:60831 biolink:ChemicalSubstance epothilone go-plus.json http://purl.obolibrary.org/obo/CHEBI_60831 CHEBI:60833 biolink:ChemicalSubstance naptalam go-plus.json http://purl.obolibrary.org/obo/CHEBI_60833 CHEBI:60836 biolink:ChemicalSubstance phytochelatin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60836 CHEBI:60835 biolink:ChemicalSubstance leucoanthocyanidin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60835 chebi_ph7_3 CHEBI:60838 biolink:ChemicalSubstance streptothricin F acid (pH 7.3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60838 chebi_ph7_3 CHEBI:60837 biolink:ChemicalSubstance 2',3'-cyclic GMP(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60837 chebi_ph7_3 CHEBI:60839 biolink:ChemicalSubstance streptothricin D acid (pH 7.3) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60839 chebi_ph7_3 CHEBI:84805 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84805 CHEBI:60841 biolink:ChemicalSubstance 2,3-dihydro-3-hydroxyanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60841 CHEBI:60843 biolink:ChemicalSubstance (2R,3R)-2,3-dihydro-3-hydroxyanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60843 CHEBI:60844 biolink:ChemicalSubstance (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60844 CHEBI:60847 biolink:ChemicalSubstance 2,3-dihydro-3-hydroxyanthranilic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60847 chebi_ph7_3 CHEBI:60849 biolink:ChemicalSubstance (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60849 chebi_ph7_3 CHEBI:60848 biolink:ChemicalSubstance (2R,3R)-2,3-dihydro-3-hydroxyanthranilic acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60848 chebi_ph7_3 CHEBI:84818 biolink:ChemicalSubstance 1-octadecanoyl-2-octadecenoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84818 chebi_ph7_3 CHEBI:84815 biolink:ChemicalSubstance 1,2-di-octadecadienoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84815 chebi_ph7_3 CHEBI:11814 biolink:ChemicalSubstance 3-hydroxy-3-methylglutaryl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_11814 CHEBI:84813 biolink:ChemicalSubstance 4-oxo-L-proline zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_84813 chebi_ph7_3 CHEBI:11812 biolink:ChemicalSubstance 3-hydroxy-3-methyl-2-oxobutanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11812 chebi_ph7_3 CHEBI:60854 biolink:ChemicalSubstance 6-amino-5-oxocyclohex-2-ene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60854 CHEBI:60858 biolink:ChemicalSubstance (1S,6R)-6-amino-5-oxocyclohex-2-ene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60858 CHEBI:60857 biolink:ChemicalSubstance (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60857 GO:1900639 biolink:BiologicalProcess positive regulation of asperfuranone biosynthetic process Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process. go-plus.json up-regulation of asperfuranone synthesis|up-regulation of asperfuranone biosynthesis|up-regulation of asperfuranone biosynthetic process|activation of asperfuranone biosynthetic process|up-regulation of asperfuranone formation|upregulation of asperfuranone anabolism|activation of asperfuranone biosynthesis|upregulation of asperfuranone synthesis|positive regulation of asperfuranone biosynthesis|upregulation of asperfuranone formation|up regulation of asperfuranone biosynthesis|up regulation of asperfuranone biosynthetic process|up regulation of asperfuranone anabolism|positive regulation of asperfuranone anabolism|up regulation of asperfuranone synthesis|positive regulation of asperfuranone synthesis|activation of asperfuranone anabolism|up regulation of asperfuranone formation|upregulation of asperfuranone biosynthesis|upregulation of asperfuranone biosynthetic process|positive regulation of asperfuranone formation|activation of asperfuranone synthesis|up-regulation of asperfuranone anabolism|activation of asperfuranone formation http://purl.obolibrary.org/obo/GO_1900639 GO:0046561 biolink:MolecularActivity obsolete penicillopepsin activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving Gly20-Glu in the B chain of insulin. Clots milk, and activates trypsinogen. go-plus.json Penicillium janthinellum acid proteinase activity|Penicillium janthinellum aspartic protease activity|Penicillium aspartic proteinase activity|Penicillium cyclopium acid proteinase activity|Penicillium roqueforti acid proteinase activity|Penicillium caseicolum aspartic proteinase activity|peptidase A activity|Penicillium expansum aspartic proteinase activity|Penicillium citrinum aspartic proteinase activity|Penicillium citrinum acid proteinase activity|Penicillium expansum acid proteinase activity|acid protease A|penicillopepsin activity|Penicillium duponti aspartic proteinase activity|Penicillium janthinellum aspartic proteinase activity http://purl.obolibrary.org/obo/GO_0046561 UBERON:0016880 biolink:AnatomicalEntity future nervous system Primordium that develops into the nervous system go-plus.json presumptive nervous system http://purl.obolibrary.org/obo/UBERON_0016880 GO:1900638 biolink:BiologicalProcess negative regulation of asperfuranone biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process. go-plus.json inhibition of asperfuranone anabolism|inhibition of asperfuranone synthesis|negative regulation of asperfuranone biosynthesis|down-regulation of asperfuranone biosynthesis|down-regulation of asperfuranone biosynthetic process|inhibition of asperfuranone formation|down regulation of asperfuranone anabolism|down regulation of asperfuranone synthesis|downregulation of asperfuranone anabolism|down regulation of asperfuranone formation|downregulation of asperfuranone biosynthesis|downregulation of asperfuranone biosynthetic process|downregulation of asperfuranone synthesis|downregulation of asperfuranone formation|down regulation of asperfuranone biosynthesis|down regulation of asperfuranone biosynthetic process|down-regulation of asperfuranone anabolism|negative regulation of asperfuranone anabolism|inhibition of asperfuranone biosynthetic process|down-regulation of asperfuranone synthesis|negative regulation of asperfuranone synthesis|inhibition of asperfuranone biosynthesis|down-regulation of asperfuranone formation|negative regulation of asperfuranone formation http://purl.obolibrary.org/obo/GO_1900638 GO:0046560 biolink:MolecularActivity obsolete scytalidopepsin B activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, cleaving Phe24-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin. go-plus.json Scytalidium lignicolum aspartic proteinase B|Ganoderma lucidum carboxyl proteinase activity|Scytalidium aspartic proteinase B activity|SLB|Ganoderma lucidum aspartic proteinase activity|scytalidopepsin B activity http://purl.obolibrary.org/obo/GO_0046560 GO:1900635 biolink:BiologicalProcess heptadecane metabolic process The chemical reactions and pathways involving heptadecane. go-plus.json heptadecane metabolism http://purl.obolibrary.org/obo/GO_1900635 GO:1900634 biolink:BiologicalProcess pentadecane biosynthetic process The chemical reactions and pathways resulting in the formation of pentadecane. go-plus.json pentadecane formation|pentadecane anabolism|pentadecane synthesis|pentadecane biosynthesis http://purl.obolibrary.org/obo/GO_1900634 GO:1900637 biolink:BiologicalProcess regulation of asperfuranone biosynthetic process Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process. go-plus.json regulation of asperfuranone anabolism|regulation of asperfuranone synthesis|regulation of asperfuranone formation|regulation of asperfuranone biosynthesis http://purl.obolibrary.org/obo/GO_1900637 GO:1900636 biolink:BiologicalProcess heptadecane biosynthetic process The chemical reactions and pathways resulting in the formation of heptadecane. go-plus.json heptadecane anabolism|heptadecane synthesis|heptadecane formation|heptadecane biosynthesis http://purl.obolibrary.org/obo/GO_1900636 GO:0046569 biolink:MolecularActivity glyoxal oxidase activity Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2. go-plus.json GLOX http://purl.obolibrary.org/obo/GO_0046569 GO:1900631 biolink:BiologicalProcess tridecane metabolic process The chemical reactions and pathways involving tridecane. go-plus.json tridecane metabolism http://purl.obolibrary.org/obo/GO_1900631 UBERON:0016888 biolink:AnatomicalEntity transitional anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016888 GO:1900630 biolink:BiologicalProcess methanophenazine biosynthetic process The chemical reactions and pathways resulting in the formation of methanophenazine. go-plus.json methanophenazine anabolism|methanophenazine synthesis|methanophenazine formation|methanophenazine biosynthesis http://purl.obolibrary.org/obo/GO_1900630 GO:0046568 biolink:MolecularActivity 3-methylbutanol:NAD(P) oxidoreductase activity Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde. MetaCyc:1.1.1.265-RXN|EC:1.1.1.265 go-plus.json isoamyl alcohol oxidase activity|3-methylbutanal reductase [NAD(P)] activity|3-methylbutyraldehyde reductase activity http://purl.obolibrary.org/obo/GO_0046568 UBERON:0016887 biolink:AnatomicalEntity entire extraembryonic component The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. go-plus.json extra-embryonic component|extraembryonic component http://purl.obolibrary.org/obo/UBERON_0016887 GO:0046567 biolink:MolecularActivity aphidicolan-16 beta-ol synthase activity Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate. EC:4.2.3.42|KEGG_REACTION:R06313|RHEA:26213|MetaCyc:RXN-10631 go-plus.json 9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming) http://purl.obolibrary.org/obo/GO_0046567 GO:1900633 biolink:BiologicalProcess pentadecane metabolic process The chemical reactions and pathways involving pentadecane. go-plus.json pentadecane metabolism http://purl.obolibrary.org/obo/GO_1900633 GO:0046566 biolink:MolecularActivity DOPA dioxygenase activity Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid. MetaCyc:RXN-8460 go-plus.json dihydroxyphenylalanine dioxygenase activity http://purl.obolibrary.org/obo/GO_0046566 GO:1900632 biolink:BiologicalProcess tridecane biosynthetic process The chemical reactions and pathways resulting in the formation of tridecane. go-plus.json tridecane biosynthesis|tridecane anabolism|tridecane synthesis|tridecane formation http://purl.obolibrary.org/obo/GO_1900632 UBERON:0016884 biolink:AnatomicalEntity shoulder joint The joint that is formed by the union of the humerus, the scapula (or shoulder blade), and the clavicle (or collarbone). Commonly thought of as a single joint, the shoulder is actually made up of two separate joints - the glenohumeral and acromioclavicular joints go-plus.json joint of shoulder region http://purl.obolibrary.org/obo/UBERON_0016884 GO:0046565 biolink:MolecularActivity 3-dehydroshikimate dehydratase activity Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate. EC:4.2.1.118|MetaCyc:DHSHIKIMATE-DEHYDRO-RXN|RHEA:24848 go-plus.json http://purl.obolibrary.org/obo/GO_0046565 UBERON:2000001 biolink:AnatomicalEntity Kupffer's vesicle Small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. Kimmel et al, 1995. Kupffer's vesicle has been compared to the mouse embryonic node. Drummond et al, 2005. go-plus.json http://purl.obolibrary.org/obo/UBERON_2000001 GO:0046564 biolink:MolecularActivity oxalate decarboxylase activity Catalysis of the reaction: H(+) + oxalate = CO(2) + formate. EC:4.1.1.2|MetaCyc:OXALATE-DECARBOXYLASE-RXN|RHEA:16509|KEGG_REACTION:R00522 go-plus.json oxalate carboxy-lyase activity|oxalate carboxy-lyase (formate-forming) http://purl.obolibrary.org/obo/GO_0046564 UBERON:0016886 biolink:AnatomicalEntity muscle tissue of terminal part of digestive tract Any muscle tissue of the distalmost portion of the digestive tract. go-plus.json rectum muscle|rectum muscle structure http://purl.obolibrary.org/obo/UBERON_0016886 GO:0046563 biolink:MolecularActivity methanol oxidase activity Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde. MetaCyc:METHANOL-OXIDASE-RXN|EC:1.1.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0046563 GO:0046562 biolink:MolecularActivity glucose oxidase activity Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2. EC:1.1.3.4|MetaCyc:GLUCOSE-OXIDASE-RXN|RHEA:11428|KEGG_REACTION:R01522 go-plus.json D-glucose-1-oxidase activity|corylophyline|beta-D-glucose:oxygen 1-oxido-reductase activity|D-glucose oxidase activity|microcid|glucose oxyhydrase activity|deoxin-1|GOD activity|beta-D-glucose:oxygen 1-oxidoreductase activity|penatin|glucose aerodehydrogenase activity|beta-D-glucose oxidase activity|beta-D-glucose:quinone oxidoreductase activity http://purl.obolibrary.org/obo/GO_0046562 UBERON:0016885 biolink:AnatomicalEntity epithelium of terminal part of digestive tract Epithelium lining the distalmost portion of the digestive tract. go-plus.json rectum epithelium http://purl.obolibrary.org/obo/UBERON_0016885 UBERON:0002241 biolink:AnatomicalEntity chondrocranium Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]. go-plus.json neurocranium|calvarium http://purl.obolibrary.org/obo/UBERON_0002241 UBERON:0002240 biolink:AnatomicalEntity spinal cord Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO) go-plus.json SpC|spinal medulla|spinal cord structure|medulla spinalis|fissura cerebrocerebellaris|cerebrocerebellar fissure|fissura cerebro-cerebellaris|cerebro-cerebellar fissure http://purl.obolibrary.org/obo/UBERON_0002240 GO:0071529 biolink:BiologicalProcess cementum mineralization The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum. go-plus.json cementum formation http://purl.obolibrary.org/obo/GO_0071529 GO:0071528 biolink:BiologicalProcess tRNA re-export from nucleus The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export. go-plus.json tRNA reexport from nucleus http://purl.obolibrary.org/obo/GO_0071528 CHEBI:35897 biolink:ChemicalSubstance but-3-enoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35897 GO:0071527 biolink:BiologicalProcess semaphorin-plexin signaling pathway involved in outflow tract morphogenesis A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis. go-plus.json semaphorin-plexin signalling pathway involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0071527 GO:0071526 biolink:BiologicalProcess semaphorin-plexin signaling pathway A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand. go-plus.json semaphorin-plexin signalling pathway http://purl.obolibrary.org/obo/GO_0071526 CHEBI:35899 biolink:ChemicalSubstance crotonate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35899 chebi_ph7_3 GO:0071525 biolink:BiologicalProcess pyrrolysine metabolic process The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine. go-plus.json pyrrolysine metabolism|monomethylamine methyltransferase cofactor lysine adduct metabolic process http://purl.obolibrary.org/obo/GO_0071525 CHEBI:59869 biolink:ChemicalSubstance L-alpha-amino acid zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59869 chebi_ph7_3 GO:0071524 biolink:BiologicalProcess pyrrolysine biosynthetic process The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine. go-plus.json pyrrolysine anabolism|monomethylamine methyltransferase cofactor lysine adduct biosynthetic process|pyrrolysine synthesis|pyrrolysine formation|pyrrolysine biosynthesis http://purl.obolibrary.org/obo/GO_0071524 CHEBI:176343 biolink:ChemicalSubstance 2,3,2',3'-tetrakis[(3R)-3-hydroxyacyl]-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176343 GO:0071523 biolink:BiologicalProcess obsolete TIR domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0071523 GO:0071522 biolink:MolecularActivity ureidoglycine aminohydrolase activity Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3. EC:3.5.3.26|MetaCyc:URUR-RXN|RHEA:25241 go-plus.json http://purl.obolibrary.org/obo/GO_0071522 GO:0071521 biolink:CellularComponent Cdc42 GTPase complex A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway. go-plus.json Ras1-Scd1-Scd2-Cdc42-Shk1 complex http://purl.obolibrary.org/obo/GO_0071521 CHEBI:59864 biolink:ChemicalSubstance depigmentation drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_59864 GO:0071520 biolink:BiologicalProcess actomyosin contractile ring assembly actin filament bundle convergence A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring. go-plus.json actin filament bundle convergence involved in actomyosin contractile ring formation|actin filament bundle convergence involved in cytokinetic actomyosin contractile ring assembly http://purl.obolibrary.org/obo/GO_0071520 CHEBI:59863 biolink:ChemicalSubstance D-fructofuranuronate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59863 chebi_ph7_3 UBERON:0002244 biolink:AnatomicalEntity premaxilla One of the bones of the upper jaw situated between and in front of the maxillae[VHOG]. go-plus.json premaxillae|os incisivum|premaxilla bone|premaxillary|premaxillary bone|incisive bone http://purl.obolibrary.org/obo/UBERON_0002244 GO:0046572 biolink:MolecularActivity versicolorin B synthase activity Catalysis of the reaction: versiconal = versicolorin B + H2O. RHEA:33859|MetaCyc:RXN-9494|EC:4.2.1.143 go-plus.json http://purl.obolibrary.org/obo/GO_0046572 GO:1900649 biolink:BiologicalProcess regulation of dehydroaustinol biosynthetic process Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process. go-plus.json regulation of dehydroaustinol biosynthesis|regulation of dehydroaustinol anabolism|regulation of dehydroaustinol synthesis|regulation of dehydroaustinol formation http://purl.obolibrary.org/obo/GO_1900649 GO:0046571 biolink:MolecularActivity aspartate-2-keto-4-methylthiobutyrate transaminase activity Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate. go-plus.json http://purl.obolibrary.org/obo/GO_0046571 GO:0046570 biolink:MolecularActivity methylthioribulose 1-phosphate dehydratase activity Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O. Reactome:R-HSA-1237140|RHEA:15549|MetaCyc:R145-RXN|EC:4.2.1.109|KEGG_REACTION:R07392 go-plus.json 5-methylthioribulose-1-phosphate 4-dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity|methylthioribulose-1-phosphate dehydratase activity|1-PMT-ribulose dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming] http://purl.obolibrary.org/obo/GO_0046570 GO:1900646 biolink:BiologicalProcess regulation of chanoclavine-I aldehyde biosynthetic process Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process. go-plus.json regulation of chanoclavine-I aldehyde synthesis|regulation of chanoclavine-I aldehyde formation|regulation of chanoclavine-I aldehyde anabolism|regulation of chanoclavine-I aldehyde biosynthesis http://purl.obolibrary.org/obo/GO_1900646 GO:1900645 biolink:BiologicalProcess positive regulation of chanoclavine-I biosynthetic process Any process that activates or increases the frequency, rate or extent of chanoclavine-I biosynthetic process. go-plus.json up-regulation of chanoclavine-I anabolism|upregulation of chanoclavine-I biosynthetic process|upregulation of chanoclavine-I biosynthesis|up-regulation of chanoclavine-I synthesis|activation of chanoclavine-I anabolism|up-regulation of chanoclavine-I formation|activation of chanoclavine-I synthesis|up regulation of chanoclavine-I biosynthetic process|positive regulation of chanoclavine-I anabolism|up regulation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I anabolism|activation of chanoclavine-I formation|activation of chanoclavine-I biosynthetic process|positive regulation of chanoclavine-I biosynthesis|positive regulation of chanoclavine-I synthesis|up regulation of chanoclavine-I synthesis|positive regulation of chanoclavine-I formation|activation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I formation|upregulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I biosynthesis|up-regulation of chanoclavine-I biosynthetic process|upregulation of chanoclavine-I synthesis|upregulation of chanoclavine-I formation http://purl.obolibrary.org/obo/GO_1900645 UBERON:0002228 biolink:AnatomicalEntity rib An intersegmental rod-shaped bone that forms in the peritoneal membrane and attach to the vertebral parapophyses. go-plus.json ribs|dorsal rib|pleural rib http://purl.obolibrary.org/obo/UBERON_0002228 GO:1900648 biolink:BiologicalProcess positive regulation of chanoclavine-I aldehyde biosynthetic process Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process. go-plus.json upregulation of chanoclavine-I aldehyde biosynthetic process|up regulation of chanoclavine-I aldehyde anabolism|upregulation of chanoclavine-I aldehyde biosynthesis|positive regulation of chanoclavine-I aldehyde anabolism|up regulation of chanoclavine-I aldehyde synthesis|positive regulation of chanoclavine-I aldehyde synthesis|up regulation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde anabolism|up-regulation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde biosynthetic process|positive regulation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde biosynthetic process|activation of chanoclavine-I aldehyde synthesis|up-regulation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde synthesis|positive regulation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde formation|up regulation of chanoclavine-I aldehyde biosynthesis|upregulation of chanoclavine-I aldehyde anabolism|up regulation of chanoclavine-I aldehyde biosynthetic process|upregulation of chanoclavine-I aldehyde synthesis|upregulation of chanoclavine-I aldehyde formation http://purl.obolibrary.org/obo/GO_1900648 GO:1900647 biolink:BiologicalProcess negative regulation of chanoclavine-I aldehyde biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process. go-plus.json inhibition of chanoclavine-I aldehyde biosynthetic process|down regulation of chanoclavine-I aldehyde formation|downregulation of chanoclavine-I aldehyde synthesis|inhibition of chanoclavine-I aldehyde biosynthesis|downregulation of chanoclavine-I aldehyde formation|down-regulation of chanoclavine-I aldehyde anabolism|negative regulation of chanoclavine-I aldehyde anabolism|down-regulation of chanoclavine-I aldehyde synthesis|negative regulation of chanoclavine-I aldehyde synthesis|down-regulation of chanoclavine-I aldehyde formation|negative regulation of chanoclavine-I aldehyde formation|down-regulation of chanoclavine-I aldehyde biosynthesis|negative regulation of chanoclavine-I aldehyde biosynthesis|down-regulation of chanoclavine-I aldehyde biosynthetic process|inhibition of chanoclavine-I aldehyde anabolism|inhibition of chanoclavine-I aldehyde synthesis|inhibition of chanoclavine-I aldehyde formation|downregulation of chanoclavine-I aldehyde biosynthesis|down regulation of chanoclavine-I aldehyde anabolism|downregulation of chanoclavine-I aldehyde biosynthetic process|downregulation of chanoclavine-I aldehyde anabolism|down regulation of chanoclavine-I aldehyde biosynthesis|down regulation of chanoclavine-I aldehyde synthesis|down regulation of chanoclavine-I aldehyde biosynthetic process http://purl.obolibrary.org/obo/GO_1900647 GO:1900642 biolink:BiologicalProcess positive regulation of austinol biosynthetic process Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process. go-plus.json upregulation of austinol anabolism|up regulation of austinol biosynthesis|up regulation of austinol biosynthetic process|activation of austinol biosynthetic process|positive regulation of austinol biosynthesis|upregulation of austinol synthesis|activation of austinol biosynthesis|upregulation of austinol formation|up-regulation of austinol anabolism|up-regulation of austinol synthesis|up-regulation of austinol biosynthesis|up-regulation of austinol biosynthetic process|activation of austinol anabolism|up-regulation of austinol formation|activation of austinol synthesis|positive regulation of austinol anabolism|activation of austinol formation|upregulation of austinol biosynthetic process|up regulation of austinol anabolism|upregulation of austinol biosynthesis|positive regulation of austinol synthesis|up regulation of austinol synthesis|positive regulation of austinol formation|up regulation of austinol formation http://purl.obolibrary.org/obo/GO_1900642 GO:1900641 biolink:BiologicalProcess negative regulation of austinol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process. go-plus.json down regulation of austinol synthesis|inhibition of austinol anabolism|down regulation of austinol formation|negative regulation of austinol biosynthesis|down-regulation of austinol biosynthesis|down-regulation of austinol biosynthetic process|inhibition of austinol synthesis|inhibition of austinol formation|inhibition of austinol biosynthetic process|down-regulation of austinol anabolism|negative regulation of austinol anabolism|inhibition of austinol biosynthesis|down-regulation of austinol synthesis|negative regulation of austinol synthesis|down-regulation of austinol formation|negative regulation of austinol formation|down regulation of austinol biosynthetic process|down regulation of austinol biosynthesis|downregulation of austinol anabolism|downregulation of austinol synthesis|downregulation of austinol biosynthesis|down regulation of austinol anabolism|downregulation of austinol biosynthetic process|downregulation of austinol formation http://purl.obolibrary.org/obo/GO_1900641 GO:0046579 biolink:BiologicalProcess positive regulation of Ras protein signal transduction Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction. go-plus.json up-regulation of Ras protein signal transduction|upregulation of Ras protein signal transduction|up regulation of Ras protein signal transduction|activation of Ras protein signal transduction|stimulation of Ras protein signal transduction http://purl.obolibrary.org/obo/GO_0046579 GO:1900644 biolink:BiologicalProcess negative regulation of chanoclavine-I biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I biosynthetic process. go-plus.json inhibition of chanoclavine-I formation|down regulation of chanoclavine-I biosynthesis|down regulation of chanoclavine-I biosynthetic process|down-regulation of chanoclavine-I anabolism|negative regulation of chanoclavine-I anabolism|downregulation of chanoclavine-I biosynthesis|downregulation of chanoclavine-I biosynthetic process|down-regulation of chanoclavine-I synthesis|negative regulation of chanoclavine-I synthesis|down-regulation of chanoclavine-I formation|negative regulation of chanoclavine-I formation|downregulation of chanoclavine-I anabolism|negative regulation of chanoclavine-I biosynthesis|down-regulation of chanoclavine-I biosynthesis|down-regulation of chanoclavine-I biosynthetic process|down regulation of chanoclavine-I anabolism|downregulation of chanoclavine-I synthesis|downregulation of chanoclavine-I formation|inhibition of chanoclavine-I biosynthetic process|down regulation of chanoclavine-I synthesis|inhibition of chanoclavine-I anabolism|down regulation of chanoclavine-I formation|inhibition of chanoclavine-I biosynthesis|inhibition of chanoclavine-I synthesis http://purl.obolibrary.org/obo/GO_1900644 UBERON:0016879 biolink:AnatomicalEntity future central nervous system Primordium that develops into the central nervous system go-plus.json future CNS|presumptive central nervous system http://purl.obolibrary.org/obo/UBERON_0016879 GO:0046578 biolink:BiologicalProcess regulation of Ras protein signal transduction Any process that modulates the frequency, rate or extent of Ras protein signal transduction. go-plus.json http://purl.obolibrary.org/obo/GO_0046578 GO:0046577 biolink:MolecularActivity long-chain-alcohol oxidase activity Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O. RHEA:22756|EC:1.1.3.20|MetaCyc:LONG-CHAIN-ALCOHOL-OXIDASE-RXN go-plus.json fatty alcohol oxidase activity|long-chain fatty acid oxidase activity|fatty alcohol:oxygen oxidoreductase activity|long-chain fatty alcohol oxidase activity|long-chain-alcohol:oxygen oxidoreductase activity http://purl.obolibrary.org/obo/GO_0046577 GO:1900643 biolink:BiologicalProcess regulation of chanoclavine-I biosynthetic process Any process that modulates the frequency, rate or extent of chanoclavine-I biosynthetic process. go-plus.json regulation of chanoclavine-I biosynthesis|regulation of chanoclavine-I anabolism|regulation of chanoclavine-I synthesis|regulation of chanoclavine-I formation http://purl.obolibrary.org/obo/GO_1900643 GO:0046576 biolink:MolecularActivity rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue. go-plus.json rhamnogalacturonase B activity http://purl.obolibrary.org/obo/GO_0046576 CHEBI:21260 biolink:ChemicalSubstance cysteic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21260 GO:0046575 biolink:MolecularActivity rhamnogalacturonan acetylesterase activity Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan. go-plus.json http://purl.obolibrary.org/obo/GO_0046575 PR:000021260 biolink:Protein renin proteolytic cleavage product A renin that has been processed by proteolytic cleavage. go-plus.json REN/ClvPrd http://purl.obolibrary.org/obo/PR_000021260 CHEBI:45212 biolink:ChemicalSubstance diphosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_45212 GO:1900640 biolink:BiologicalProcess regulation of austinol biosynthetic process Any process that modulates the frequency, rate or extent of austinol biosynthetic process. go-plus.json regulation of austinol formation|regulation of austinol anabolism|regulation of austinol biosynthesis|regulation of austinol synthesis http://purl.obolibrary.org/obo/GO_1900640 GO:0046574 biolink:MolecularActivity glycuronidase activity Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid. go-plus.json glucuronyl hydrolase activity http://purl.obolibrary.org/obo/GO_0046574 GO:0046573 biolink:MolecularActivity lactonohydrolase activity Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group. go-plus.json http://purl.obolibrary.org/obo/GO_0046573 GO:0071519 biolink:BiologicalProcess actomyosin contractile ring actin filament bundle assembly A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis. go-plus.json actin filament bundle assembly involved in cytokinetic actomyosin contractile ring assembly|actin filament bundle assembly involved in actomyosin contractile ring formation http://purl.obolibrary.org/obo/GO_0071519 GO:0071518 biolink:MolecularActivity autoinducer-2 kinase activity Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP. MetaCyc:RXN0-5461|RHEA:15377 go-plus.json 4,5-dihydroxy-pentane-2,3-dione kinase activity http://purl.obolibrary.org/obo/GO_0071518 GO:0071517 biolink:BiologicalProcess maintenance of imprinting at mating-type locus Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication. go-plus.json mating type determination, maintenance of imprinting http://purl.obolibrary.org/obo/GO_0071517 GO:0071516 biolink:BiologicalProcess establishment of imprinting at mating-type locus The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication. go-plus.json mating type determination, establishment of imprinting http://purl.obolibrary.org/obo/GO_0071516 GO:0071515 biolink:BiologicalProcess genetic imprinting at mating-type locus A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication. go-plus.json mating type determination, imprinting http://purl.obolibrary.org/obo/GO_0071515 GO:0071514 biolink:BiologicalProcess genetic imprinting Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. go-plus.json DNA imprinting http://purl.obolibrary.org/obo/GO_0071514 GO:0071513 biolink:CellularComponent phosphopantothenoylcysteine decarboxylase complex A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. go-plus.json http://purl.obolibrary.org/obo/GO_0071513 GO:0071512 biolink:BiologicalProcess obsolete MAPK import into nucleus involved in conjugation with cellular fusion OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion. go-plus.json conjugation with cellular fusion, nuclear translocation of MAPK|MAPK import into nucleus involved in mating response|conjugation with cellular fusion, MAPK import into nucleus|nuclear translocation of MAPK involved in mating response|nuclear translocation of MAPK involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0071512 UBERON:0002237 biolink:AnatomicalEntity true rib A rib that is ventrally connected to the sternum. go-plus.json costae verae|costa vera http://purl.obolibrary.org/obo/UBERON_0002237 GO:0071511 biolink:BiologicalProcess obsolete inactivation of MAPK activity involved in conjugation with cellular fusion OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion. go-plus.json conjugation with cellular fusion, termination of MAPK activity|conjugation with cellular fusion, inactivation of MAPK activity|termination of MAPK activity during conjugation with cellular fusion|inactivation of MAPK activity involved in mating response http://purl.obolibrary.org/obo/GO_0071511 GO:0071510 biolink:BiologicalProcess obsolete activation of MAPKKK activity involved in conjugation with cellular fusion OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion. go-plus.json activation of MAP kinase kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAPKKK activity|activation of MAPKKK activity involved in mating response|conjugation with cellular fusion, activation of MAP kinase kinase kinase activity http://purl.obolibrary.org/obo/GO_0071510 UBERON:0002234 biolink:AnatomicalEntity proximal phalanx of manus A proximal phalanx that is part of a finger [Automatically generated definition]. go-plus.json proximal phalanx of manual digit|proximal phalanx of hand|phalanx proximalis manus|proximal phalanx of fore digit|proximal manual phalanx|proximal phalanx of finger|hand proximal phalanx http://purl.obolibrary.org/obo/UBERON_0002234 GO:0095500 biolink:BiologicalProcess acetylcholine receptor signaling pathway The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands. go-plus.json acetylcholine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0095500 GO:0046583 biolink:MolecularActivity cation efflux transmembrane transporter activity Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane. go-plus.json cation efflux permease activity http://purl.obolibrary.org/obo/GO_0046583 GO:0046582 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046582 GO:0046581 biolink:CellularComponent intercellular canaliculus An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates. go-plus.json http://purl.obolibrary.org/obo/GO_0046581 GO:0046580 biolink:BiologicalProcess negative regulation of Ras protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction. go-plus.json downregulation of Ras protein signal transduction|down-regulation of Ras protein signal transduction|inhibition of Ras protein signal transduction|down regulation of Ras protein signal transduction http://purl.obolibrary.org/obo/GO_0046580 GO:1900657 biolink:BiologicalProcess positive regulation of diorcinol biosynthetic process Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process. go-plus.json up-regulation of diorcinol synthesis|up-regulation of diorcinol formation|positive regulation of diorcinol biosynthesis|up regulation of diorcinol biosynthetic process|up regulation of diorcinol biosynthesis|upregulation of diorcinol anabolism|upregulation of diorcinol synthesis|upregulation of diorcinol formation|up regulation of diorcinol anabolism|upregulation of diorcinol biosynthetic process|upregulation of diorcinol biosynthesis|positive regulation of diorcinol anabolism|up regulation of diorcinol synthesis|positive regulation of diorcinol synthesis|up regulation of diorcinol formation|activation of diorcinol anabolism|up-regulation of diorcinol biosynthetic process|up-regulation of diorcinol biosynthesis|positive regulation of diorcinol formation|activation of diorcinol biosynthetic process|activation of diorcinol synthesis|up-regulation of diorcinol anabolism|activation of diorcinol formation|activation of diorcinol biosynthesis http://purl.obolibrary.org/obo/GO_1900657 GO:1900656 biolink:BiologicalProcess negative regulation of diorcinol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process. go-plus.json inhibition of diorcinol anabolism|inhibition of diorcinol synthesis|downregulation of diorcinol biosynthetic process|downregulation of diorcinol biosynthesis|inhibition of diorcinol formation|down regulation of diorcinol anabolism|down regulation of diorcinol biosynthetic process|downregulation of diorcinol anabolism|down regulation of diorcinol biosynthesis|down regulation of diorcinol synthesis|inhibition of diorcinol biosynthetic process|down regulation of diorcinol formation|downregulation of diorcinol synthesis|inhibition of diorcinol biosynthesis|downregulation of diorcinol formation|down-regulation of diorcinol anabolism|negative regulation of diorcinol anabolism|down-regulation of diorcinol synthesis|negative regulation of diorcinol synthesis|down-regulation of diorcinol formation|negative regulation of diorcinol formation|negative regulation of diorcinol biosynthesis|down-regulation of diorcinol biosynthesis|down-regulation of diorcinol biosynthetic process http://purl.obolibrary.org/obo/GO_1900656 UBERON:0002217 biolink:AnatomicalEntity synovial joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA] go-plus.json diarthrosis joint|diarthroses|diarthrosis|articulatio synoviale|diarthrodial joints http://purl.obolibrary.org/obo/UBERON_0002217 GO:1900659 biolink:BiologicalProcess negative regulation of emericellamide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process. go-plus.json downregulation of emericellamide formation|down regulation of emericellamide synthesis|down regulation of emericellamide formation|inhibition of emericellamide anabolism|inhibition of emericellamide synthesis|down-regulation of emericellamide biosynthetic process|negative regulation of emericellamide biosynthesis|down-regulation of emericellamide biosynthesis|inhibition of emericellamide formation|inhibition of emericellamide biosynthetic process|negative regulation of emericellamide anabolism|down-regulation of emericellamide anabolism|negative regulation of emericellamide synthesis|inhibition of emericellamide biosynthesis|down-regulation of emericellamide synthesis|negative regulation of emericellamide formation|down-regulation of emericellamide formation|downregulation of emericellamide anabolism|down regulation of emericellamide biosynthesis|down regulation of emericellamide biosynthetic process|down regulation of emericellamide anabolism|downregulation of emericellamide synthesis|downregulation of emericellamide biosynthesis|downregulation of emericellamide biosynthetic process http://purl.obolibrary.org/obo/GO_1900659 GO:1900658 biolink:BiologicalProcess regulation of emericellamide biosynthetic process Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process. go-plus.json regulation of emericellamide formation|regulation of emericellamide anabolism|regulation of emericellamide biosynthesis|regulation of emericellamide synthesis http://purl.obolibrary.org/obo/GO_1900658 CHEBI:59848 biolink:ChemicalSubstance thia fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59848 GO:1900653 biolink:BiologicalProcess negative regulation of demethylkotanin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process. go-plus.json down regulation of demethylkotanin anabolism|inhibition of demethylkotanin formation|down-regulation of demethylkotanin biosynthetic process|down-regulation of demethylkotanin biosynthesis|negative regulation of demethylkotanin biosynthesis|downregulation of demethylkotanin anabolism|down regulation of demethylkotanin synthesis|down regulation of demethylkotanin formation|downregulation of demethylkotanin synthesis|downregulation of demethylkotanin biosynthesis|downregulation of demethylkotanin biosynthetic process|downregulation of demethylkotanin formation|down-regulation of demethylkotanin anabolism|negative regulation of demethylkotanin anabolism|down regulation of demethylkotanin biosynthetic process|down regulation of demethylkotanin biosynthesis|inhibition of demethylkotanin biosynthetic process|down-regulation of demethylkotanin synthesis|negative regulation of demethylkotanin synthesis|down-regulation of demethylkotanin formation|negative regulation of demethylkotanin formation|inhibition of demethylkotanin biosynthesis|inhibition of demethylkotanin anabolism|inhibition of demethylkotanin synthesis http://purl.obolibrary.org/obo/GO_1900653 GO:1900652 biolink:BiologicalProcess regulation of demethylkotanin biosynthetic process Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process. go-plus.json regulation of demethylkotanin anabolism|regulation of demethylkotanin synthesis|regulation of demethylkotanin formation|regulation of demethylkotanin biosynthesis http://purl.obolibrary.org/obo/GO_1900652 GO:0046589 biolink:MolecularActivity ribonuclease T1 activity Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates. MetaCyc:3.1.27.3-RXN|EC:4.6.1.24 go-plus.json guanyloribonuclease activity|RNase T1 activity|ribonuclease F1|ribonuclease C2|ribonuclease SA|RNase T1|RNase N1 activity|guanyl-specific RNase activity|RNase N2 activity|ribonuclease N1|binase activity|ribonuclease N3|ribonuclease guaninenucleotido-2'-transferase (cyclizing)|RNase G|ribonuclease U1|Aspergillus oryzae ribonuclease activity|ribonuclease Ch|RNase Sa|RNase F1|ribonuclease PP1 http://purl.obolibrary.org/obo/GO_0046589 GO:1900655 biolink:BiologicalProcess regulation of diorcinol biosynthetic process Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process. go-plus.json regulation of diorcinol anabolism|regulation of diorcinol biosynthesis|regulation of diorcinol synthesis|regulation of diorcinol formation http://purl.obolibrary.org/obo/GO_1900655 GO:1900654 biolink:BiologicalProcess positive regulation of demethylkotanin biosynthetic process Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process. go-plus.json upregulation of demethylkotanin anabolism|activation of demethylkotanin biosynthesis|upregulation of demethylkotanin synthesis|upregulation of demethylkotanin formation|positive regulation of demethylkotanin biosynthesis|up regulation of demethylkotanin anabolism|up regulation of demethylkotanin biosynthesis|up regulation of demethylkotanin biosynthetic process|positive regulation of demethylkotanin anabolism|up regulation of demethylkotanin synthesis|positive regulation of demethylkotanin synthesis|up regulation of demethylkotanin formation|activation of demethylkotanin anabolism|positive regulation of demethylkotanin formation|upregulation of demethylkotanin biosynthetic process|upregulation of demethylkotanin biosynthesis|activation of demethylkotanin synthesis|up-regulation of demethylkotanin anabolism|activation of demethylkotanin formation|up-regulation of demethylkotanin synthesis|activation of demethylkotanin biosynthetic process|up-regulation of demethylkotanin biosynthesis|up-regulation of demethylkotanin biosynthetic process|up-regulation of demethylkotanin formation http://purl.obolibrary.org/obo/GO_1900654 GO:0046588 biolink:BiologicalProcess negative regulation of calcium-dependent cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion. go-plus.json down-regulation of calcium-dependent cell-cell adhesion|downregulation of calcium-dependent cell-cell adhesion|down regulation of calcium-dependent cell-cell adhesion|inhibition of calcium-dependent cell-cell adhesion http://purl.obolibrary.org/obo/GO_0046588 GO:0046587 biolink:BiologicalProcess positive regulation of calcium-dependent cell-cell adhesion Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion. go-plus.json up regulation of calcium-dependent cell-cell adhesion|upregulation of calcium-dependent cell-cell adhesion|stimulation of calcium-dependent cell-cell adhesion|up-regulation of calcium-dependent cell-cell adhesion|activation of calcium-dependent cell-cell adhesion http://purl.obolibrary.org/obo/GO_0046587 GO:0046586 biolink:BiologicalProcess regulation of calcium-dependent cell-cell adhesion Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0046586 GO:1900651 biolink:BiologicalProcess positive regulation of dehydroaustinol biosynthetic process Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process. go-plus.json activation of dehydroaustinol biosynthetic process|upregulation of dehydroaustinol formation|up regulation of dehydroaustinol anabolism|activation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol anabolism|up regulation of dehydroaustinol synthesis|positive regulation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol synthesis|up regulation of dehydroaustinol formation|activation of dehydroaustinol anabolism|up regulation of dehydroaustinol biosynthetic process|up regulation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol formation|activation of dehydroaustinol synthesis|up-regulation of dehydroaustinol anabolism|activation of dehydroaustinol formation|up-regulation of dehydroaustinol synthesis|upregulation of dehydroaustinol biosynthetic process|upregulation of dehydroaustinol biosynthesis|up-regulation of dehydroaustinol formation|upregulation of dehydroaustinol anabolism|upregulation of dehydroaustinol synthesis|up-regulation of dehydroaustinol biosynthetic process|up-regulation of dehydroaustinol biosynthesis http://purl.obolibrary.org/obo/GO_1900651 GO:0046585 biolink:BiologicalProcess enniatin biosynthetic process The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores. go-plus.json enniatin anabolism|enniatin biosynthesis|enniatin synthesis|enniatin formation http://purl.obolibrary.org/obo/GO_0046585 GO:1900650 biolink:BiologicalProcess negative regulation of dehydroaustinol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process. go-plus.json downregulation of dehydroaustinol anabolism|down regulation of dehydroaustinol synthesis|down regulation of dehydroaustinol formation|downregulation of dehydroaustinol synthesis|down-regulation of dehydroaustinol biosynthesis|down-regulation of dehydroaustinol biosynthetic process|negative regulation of dehydroaustinol biosynthesis|downregulation of dehydroaustinol formation|negative regulation of dehydroaustinol anabolism|down-regulation of dehydroaustinol anabolism|negative regulation of dehydroaustinol synthesis|down-regulation of dehydroaustinol synthesis|downregulation of dehydroaustinol biosynthesis|downregulation of dehydroaustinol biosynthetic process|negative regulation of dehydroaustinol formation|down-regulation of dehydroaustinol formation|down regulation of dehydroaustinol biosynthetic process|down regulation of dehydroaustinol biosynthesis|inhibition of dehydroaustinol biosynthetic process|inhibition of dehydroaustinol anabolism|inhibition of dehydroaustinol biosynthesis|inhibition of dehydroaustinol synthesis|inhibition of dehydroaustinol formation|down regulation of dehydroaustinol anabolism http://purl.obolibrary.org/obo/GO_1900650 GO:0046584 biolink:BiologicalProcess enniatin metabolic process The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores. go-plus.json enniatin metabolism http://purl.obolibrary.org/obo/GO_0046584 CHEBI:35871 biolink:ChemicalSubstance oxo monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35871 CHEBI:35873 biolink:ChemicalSubstance carboxylic anhydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_35873 CHEBI:35875 biolink:ChemicalSubstance imidazopyrimidine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35875 GO:0071549 biolink:BiologicalProcess cellular response to dexamethasone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071549 GO:0071548 biolink:BiologicalProcess response to dexamethasone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. go-plus.json response to dexamethasone stimulus http://purl.obolibrary.org/obo/GO_0071548 GO:0071547 biolink:CellularComponent piP-body A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0071547 CHEBI:21239 biolink:ChemicalSubstance arogenic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21239 UBERON:0002224 biolink:AnatomicalEntity thoracic cavity The part of the coelemic cavity lumen that is enclosed by the walls of the thorax. go-plus.json cavitas thoracis|cavity of thorax|pectoral cavity|cavity of chest|thoracic lumen|chest cavity|space of thoracic compartment http://purl.obolibrary.org/obo/UBERON_0002224 GO:0071546 biolink:CellularComponent pi-body A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes. go-plus.json intermitochondrial cement http://purl.obolibrary.org/obo/GO_0071546 GO:0071545 biolink:BiologicalProcess inositol phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. go-plus.json inositol phosphate degradation|inositol phosphate breakdown|inositol phosphate catabolism|myo-inositol phosphate catabolic process http://purl.obolibrary.org/obo/GO_0071545 CHEBI:59845 biolink:ChemicalSubstance 3-hydroxy fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59845 GO:0071544 biolink:BiologicalProcess diphosphoinositol polyphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. go-plus.json diphosphoinositol polyphosphate breakdown|diphosphoinositol polyphosphate catabolism|diphosphoinositol polyphosphate degradation http://purl.obolibrary.org/obo/GO_0071544 GO:0071543 biolink:BiologicalProcess diphosphoinositol polyphosphate metabolic process The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. go-plus.json diphosphoinositol polyphosphate metabolism http://purl.obolibrary.org/obo/GO_0071543 GO:0071542 biolink:BiologicalProcess dopaminergic neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. go-plus.json http://purl.obolibrary.org/obo/GO_0071542 GO:0071541 biolink:CellularComponent eukaryotic translation initiation factor 3 complex, eIF3m An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m. go-plus.json eIF3m-containing eukaryotic translation initiation factor 3 complex http://purl.obolibrary.org/obo/GO_0071541 UBERON:0002222 biolink:AnatomicalEntity perichondrium Fibrous connective tissue that surrounds cartilage. go-plus.json cartilage connective tissue|perichondral region of cartilage|perichondral region of cartilage element http://purl.obolibrary.org/obo/UBERON_0002222 GO:0071540 biolink:CellularComponent eukaryotic translation initiation factor 3 complex, eIF3e An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e. go-plus.json eIF3e-containing eukaryotic translation initiation factor 3 complex http://purl.obolibrary.org/obo/GO_0071540 GO:0046594 biolink:BiologicalProcess maintenance of pole plasm mRNA location The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster. go-plus.json maintenance of oocyte pole plasm mRNA localization|maintenance of pole plasm mRNA localization http://purl.obolibrary.org/obo/GO_0046594 GO:0046593 biolink:MolecularActivity mandelonitrile lyase activity Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde. MetaCyc:MANDELONITRILE-LYASE-RXN|EC:4.1.2.10|RHEA:18313 go-plus.json D-alpha-hydroxynitrile lyase activity|mandelonitrile benzaldehyde-lyase (cyanide-forming)|mandelonitrile benzaldehyde-lyase activity|hydroxynitrile lyase activity|D-oxynitrilase activity|(R)-oxynitrilase activity http://purl.obolibrary.org/obo/GO_0046593 GO:0046592 biolink:MolecularActivity polyamine oxidase activity Catalysis of the oxidative degradation or interconversion of polyamines. MetaCyc:POLYAMINE-OXIDASE-RXN go-plus.json 1-N-acetylspermidine:oxygen oxidoreductase (deaminating)|N1-acetylspermidine:oxygen oxidoreductase (deaminating) http://purl.obolibrary.org/obo/GO_0046592 GO:0046591 biolink:BiologicalProcess obsolete embryonic leg joint morphogenesis OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. go-plus.json embryonic leg joint morphogenesis http://purl.obolibrary.org/obo/GO_0046591 GO:1900668 biolink:BiologicalProcess negative regulation of endocrocin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process. go-plus.json downregulation of endocrocin biosynthesis|downregulation of endocrocin biosynthetic process|inhibition of endocrocin synthesis|inhibition of endocrocin formation|down-regulation of endocrocin biosynthesis|negative regulation of endocrocin biosynthesis|down-regulation of endocrocin anabolism|negative regulation of endocrocin anabolism|down-regulation of endocrocin biosynthetic process|negative regulation of endocrocin synthesis|down-regulation of endocrocin synthesis|down-regulation of endocrocin formation|inhibition of endocrocin biosynthetic process|negative regulation of endocrocin formation|downregulation of endocrocin anabolism|inhibition of endocrocin biosynthesis|down regulation of endocrocin anabolism|downregulation of endocrocin synthesis|downregulation of endocrocin formation|down regulation of endocrocin synthesis|down regulation of endocrocin biosynthesis|down regulation of endocrocin biosynthetic process|inhibition of endocrocin anabolism|down regulation of endocrocin formation http://purl.obolibrary.org/obo/GO_1900668 GO:0046590 biolink:BiologicalProcess obsolete embryonic leg morphogenesis OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands. go-plus.json embryonic leg morphogenesis http://purl.obolibrary.org/obo/GO_0046590 UBERON:0002206 biolink:AnatomicalEntity mammillary body One of two hemispherical bulges on the base of the posterior hypothalamus (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg 455). go-plus.json mammillary area|corpus mammillare|corpora mammillaria|corpus mamillare|corpus mamillare|corpora mamillaria|corpus mamillaris|MMB http://purl.obolibrary.org/obo/UBERON_0002206 GO:1900667 biolink:BiologicalProcess regulation of endocrocin biosynthetic process Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process. go-plus.json regulation of endocrocin anabolism|regulation of endocrocin synthesis|regulation of endocrocin formation|regulation of endocrocin biosynthesis http://purl.obolibrary.org/obo/GO_1900667 UBERON:0002209 biolink:AnatomicalEntity fibrous joint Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA] go-plus.json articulatio fibrosa|junctura fibrosa http://purl.obolibrary.org/obo/UBERON_0002209 GO:1900669 biolink:BiologicalProcess positive regulation of endocrocin biosynthetic process Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process. go-plus.json upregulation of endocrocin formation|up-regulation of endocrocin anabolism|up regulation of endocrocin biosynthetic process|up regulation of endocrocin biosynthesis|activation of endocrocin biosynthetic process|positive regulation of endocrocin biosynthesis|up-regulation of endocrocin synthesis|activation of endocrocin anabolism|up-regulation of endocrocin formation|activation of endocrocin biosynthesis|activation of endocrocin synthesis|positive regulation of endocrocin anabolism|up regulation of endocrocin anabolism|activation of endocrocin formation|up-regulation of endocrocin biosynthesis|up-regulation of endocrocin biosynthetic process|positive regulation of endocrocin synthesis|up regulation of endocrocin synthesis|positive regulation of endocrocin formation|up regulation of endocrocin formation|upregulation of endocrocin biosynthetic process|upregulation of endocrocin anabolism|upregulation of endocrocin biosynthesis|upregulation of endocrocin synthesis http://purl.obolibrary.org/obo/GO_1900669 GO:1900664 biolink:BiologicalProcess regulation of emodin biosynthetic process Any process that modulates the frequency, rate or extent of emodin biosynthetic process. go-plus.json regulation of emodin biosynthesis|regulation of emodin anabolism|regulation of emodin synthesis|regulation of emodin formation http://purl.obolibrary.org/obo/GO_1900664 UBERON:0016855 biolink:AnatomicalEntity ventral part of optic cup The ventral region of the optic cup that gives rise to the ventral part of the retina. go-plus.json ventral region of optic cup|ventral optic cup http://purl.obolibrary.org/obo/UBERON_0016855 RO:0004047 biolink:OntologyClass causally upstream of or within, positive effect RO:0004047 go-plus.json http://purl.obolibrary.org/obo/RO_0004047 GO:1900663 biolink:BiologicalProcess positive regulation of emericellamide A biosynthetic process Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process. go-plus.json up regulation of emericellamide A anabolism|activation of emericellamide A formation|positive regulation of emericellamide A synthesis|up regulation of emericellamide A synthesis|upregulation of emericellamide A biosynthesis|upregulation of emericellamide A biosynthetic process|positive regulation of emericellamide A formation|up regulation of emericellamide A formation|upregulation of emericellamide A anabolism|up regulation of emericellamide A biosynthesis|up regulation of emericellamide A biosynthetic process|upregulation of emericellamide A synthesis|positive regulation of emericellamide A biosynthesis|activation of emericellamide A biosynthetic process|upregulation of emericellamide A formation|up-regulation of emericellamide A anabolism|activation of emericellamide A biosynthesis|up-regulation of emericellamide A synthesis|activation of emericellamide A anabolism|up-regulation of emericellamide A formation|up-regulation of emericellamide A biosynthesis|up-regulation of emericellamide A biosynthetic process|activation of emericellamide A synthesis|positive regulation of emericellamide A anabolism http://purl.obolibrary.org/obo/GO_1900663 RO:0004046 biolink:OntologyClass causally upstream of or within, negative effect RO:0004046 go-plus.json http://purl.obolibrary.org/obo/RO_0004046 UBERON:0016854 biolink:AnatomicalEntity dorsal part of optic cup The dorsal region of the optic cup that gives rise to the dorsal part of the retina. go-plus.json dorsal region of optic cup|dorsal optic cup http://purl.obolibrary.org/obo/UBERON_0016854 GO:1900666 biolink:BiologicalProcess positive regulation of emodin biosynthetic process Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process. go-plus.json up-regulation of emodin synthesis|activation of emodin anabolism|up-regulation of emodin formation|activation of emodin synthesis|positive regulation of emodin anabolism|up regulation of emodin biosynthetic process|up regulation of emodin biosynthesis|up regulation of emodin anabolism|activation of emodin formation|activation of emodin biosynthetic process|positive regulation of emodin synthesis|positive regulation of emodin biosynthesis|up regulation of emodin synthesis|positive regulation of emodin formation|activation of emodin biosynthesis|up regulation of emodin formation|upregulation of emodin anabolism|up-regulation of emodin biosynthesis|up-regulation of emodin biosynthetic process|upregulation of emodin synthesis|upregulation of emodin formation|up-regulation of emodin anabolism|upregulation of emodin biosynthesis|upregulation of emodin biosynthetic process http://purl.obolibrary.org/obo/GO_1900666 GO:1900665 biolink:BiologicalProcess negative regulation of emodin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process. go-plus.json down regulation of emodin biosynthetic process|down regulation of emodin biosynthesis|negative regulation of emodin anabolism|down-regulation of emodin anabolism|downregulation of emodin biosynthesis|downregulation of emodin biosynthetic process|negative regulation of emodin synthesis|down-regulation of emodin synthesis|negative regulation of emodin formation|down-regulation of emodin formation|downregulation of emodin anabolism|down-regulation of emodin biosynthetic process|down-regulation of emodin biosynthesis|negative regulation of emodin biosynthesis|down regulation of emodin anabolism|downregulation of emodin synthesis|downregulation of emodin formation|down regulation of emodin synthesis|inhibition of emodin biosynthetic process|down regulation of emodin formation|inhibition of emodin anabolism|inhibition of emodin biosynthesis|inhibition of emodin synthesis|inhibition of emodin formation http://purl.obolibrary.org/obo/GO_1900665 GO:0046599 biolink:BiologicalProcess regulation of centriole replication Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole. go-plus.json http://purl.obolibrary.org/obo/GO_0046599 GO:1900660 biolink:BiologicalProcess positive regulation of emericellamide biosynthetic process Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process. go-plus.json up regulation of emericellamide anabolism|activation of emericellamide formation|positive regulation of emericellamide synthesis|upregulation of emericellamide biosynthesis|upregulation of emericellamide biosynthetic process|up regulation of emericellamide synthesis|positive regulation of emericellamide formation|up regulation of emericellamide formation|upregulation of emericellamide anabolism|up regulation of emericellamide biosynthesis|up regulation of emericellamide biosynthetic process|activation of emericellamide biosynthetic process|positive regulation of emericellamide biosynthesis|upregulation of emericellamide synthesis|upregulation of emericellamide formation|up-regulation of emericellamide anabolism|activation of emericellamide biosynthesis|up-regulation of emericellamide synthesis|up-regulation of emericellamide biosynthetic process|activation of emericellamide anabolism|up-regulation of emericellamide biosynthesis|up-regulation of emericellamide formation|activation of emericellamide synthesis|positive regulation of emericellamide anabolism http://purl.obolibrary.org/obo/GO_1900660 GO:0046598 biolink:BiologicalProcess positive regulation of viral entry into host cell Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell. go-plus.json positive regulation of viral penetration into host cell http://purl.obolibrary.org/obo/GO_0046598 GO:0046597 biolink:BiologicalProcess negative regulation of viral entry into host cell Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell. go-plus.json negative regulation of viral penetration into host cell http://purl.obolibrary.org/obo/GO_0046597 GO:1900662 biolink:BiologicalProcess negative regulation of emericellamide A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process. go-plus.json inhibition of emericellamide A biosynthesis|down-regulation of emericellamide A formation|negative regulation of emericellamide A formation|downregulation of emericellamide A anabolism|down regulation of emericellamide A biosynthesis|down regulation of emericellamide A anabolism|downregulation of emericellamide A synthesis|down regulation of emericellamide A biosynthetic process|downregulation of emericellamide A formation|downregulation of emericellamide A biosynthesis|downregulation of emericellamide A biosynthetic process|down regulation of emericellamide A synthesis|down regulation of emericellamide A formation|inhibition of emericellamide A anabolism|inhibition of emericellamide A synthesis|negative regulation of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthetic process|inhibition of emericellamide A formation|inhibition of emericellamide A biosynthetic process|down-regulation of emericellamide A anabolism|negative regulation of emericellamide A anabolism|down-regulation of emericellamide A synthesis|negative regulation of emericellamide A synthesis http://purl.obolibrary.org/obo/GO_1900662 GO:0046596 biolink:BiologicalProcess regulation of viral entry into host cell Any process that modulates the frequency, rate or extent of the viral entry into the host cell. go-plus.json viral escort protein|regulation of viral penetration into host cell http://purl.obolibrary.org/obo/GO_0046596 GO:0046595 biolink:BiologicalProcess establishment of pole plasm mRNA localization Any process that results in the directed movement of mRNA to the oocyte pole plasm. go-plus.json establishment of oocyte pole plasm mRNA localization|establishment of pole plasm mRNA localisation http://purl.obolibrary.org/obo/GO_0046595 GO:1900661 biolink:BiologicalProcess regulation of emericellamide A biosynthetic process Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process. go-plus.json regulation of emericellamide A anabolism|regulation of emericellamide A synthesis|regulation of emericellamide A biosynthesis|regulation of emericellamide A formation http://purl.obolibrary.org/obo/GO_1900661 GO:0071539 biolink:BiologicalProcess protein localization to centrosome A process in which a protein is transported to, or maintained at, the centrosome. go-plus.json protein localisation to centrosome http://purl.obolibrary.org/obo/GO_0071539 GO:0071538 biolink:BiologicalProcess obsolete SH2 domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction. go-plus.json http://purl.obolibrary.org/obo/GO_0071538 GO:0071537 biolink:BiologicalProcess obsolete C3HC4-type RING finger domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction. go-plus.json zinc finger C3HC4 type domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071537 GO:0071536 biolink:BiologicalProcess obsolete RING-like zinc finger domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction. go-plus.json RING-like domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071536 CHEBI:59836 biolink:ChemicalSubstance oxo fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59836 GO:0071535 biolink:MolecularActivity RING-like zinc finger domain binding Binding to a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain. go-plus.json http://purl.obolibrary.org/obo/GO_0071535 CHEBI:59835 biolink:ChemicalSubstance hydroxy fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59835 UBERON:0002213 biolink:AnatomicalEntity cartilaginous joint Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA] go-plus.json articulatio cartilaginea|junctura cartilaginea http://purl.obolibrary.org/obo/UBERON_0002213 GO:0071534 biolink:BiologicalProcess obsolete zf-TRAF domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction. go-plus.json zinc-finger-TRAF domain-mediated complex assembly|TRAF-type zinc finger domain-mediated complex assembly|zinc finger TRAF-type domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071534 UBERON:0002216 biolink:AnatomicalEntity symphysis Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA] go-plus.json secondary cartilaginous joint http://purl.obolibrary.org/obo/UBERON_0002216 GO:0071533 biolink:BiologicalProcess obsolete ankyrin repeat-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction. go-plus.json ANK repeat-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071533 UBERON:0002215 biolink:AnatomicalEntity synchondrosis Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA] go-plus.json epiphysial cartilage|primary cartilaginous joint|cartilago epiphysialis http://purl.obolibrary.org/obo/UBERON_0002215 GO:0071532 biolink:MolecularActivity ankyrin repeat binding Binding to an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure. go-plus.json ANK repeat binding http://purl.obolibrary.org/obo/GO_0071532 UBERON:0002210 biolink:AnatomicalEntity syndesmosis Fibrous joint in which the articulating bones or cartilages of the vertebral column and the limbs as well as articulating ossicles, are connected by skeletal ligaments or membranes. Examples: Intervertebral syndesmosis, inferior tibiofibular joint.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0002210 GO:0071531 biolink:BiologicalProcess obsolete Rel homology domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a Rel homology domain (RHD) interaction. go-plus.json RHD domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071531 GO:0071530 biolink:BiologicalProcess obsolete FHA domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction. go-plus.json forkhead-associated domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071530 CHEBI:35881 biolink:ChemicalSubstance pnictogen hydride go-plus.json http://purl.obolibrary.org/obo/CHEBI_35881 UBERON:0002211 biolink:AnatomicalEntity nerve root A continuation of the neuron projection bundle component of a nerve inside, crossing or immediately outside the central nervous system. go-plus.json radix nervi|initial segment of nerve http://purl.obolibrary.org/obo/UBERON_0002211 GO:0071561 biolink:CellularComponent nucleus-vacuole junction An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. go-plus.json nucleus-vacuole membrane contact site|NVJ|NV junction http://purl.obolibrary.org/obo/GO_0071561 GO:0071560 biolink:BiologicalProcess cellular response to transforming growth factor beta stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. go-plus.json cellular response to TGF-beta stimulus|cellular response to TGFbeta stimulus http://purl.obolibrary.org/obo/GO_0071560 GO:1900679 biolink:BiologicalProcess negative regulation of ferricrocin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process. go-plus.json inhibition of ferricrocin biosynthetic process|inhibition of ferricrocin biosynthetic process, peptide modification|down regulation of ferricrocin biosynthetic process, peptide formation|negative regulation of ferricrocin synthesis|down-regulation of ferricrocin synthesis|negative regulation of ferricrocin formation|down-regulation of ferricrocin formation|downregulation of ferricrocin biosynthetic process, peptide formation|inhibition of ferricrocin biosynthesis|inhibition of ferricrocin anabolism|negative regulation of ferricrocin biosynthetic process, peptide modification|inhibition of ferricrocin synthesis|down-regulation of ferricrocin biosynthetic process, peptide modification|down-regulation of ferricrocin biosynthetic process, peptide formation|negative regulation of ferricrocin biosynthetic process, peptide formation|down regulation of ferricrocin anabolism|inhibition of ferricrocin formation|down-regulation of ferricrocin biosynthesis|down-regulation of ferricrocin biosynthetic process|negative regulation of ferricrocin biosynthesis|down regulation of ferricrocin synthesis|downregulation of ferricrocin anabolism|downregulation of ferricrocin biosynthetic process, peptide modification|down regulation of ferricrocin formation|downregulation of ferricrocin synthesis|downregulation of ferricrocin biosynthesis|downregulation of ferricrocin biosynthetic process|inhibition of ferricrocin biosynthetic process, peptide formation|down regulation of ferricrocin biosynthetic process, peptide modification|downregulation of ferricrocin formation|negative regulation of ferricrocin anabolism|down-regulation of ferricrocin anabolism|down regulation of ferricrocin biosynthetic process|down regulation of ferricrocin biosynthesis http://purl.obolibrary.org/obo/GO_1900679 GO:1900678 biolink:BiologicalProcess regulation of ferricrocin biosynthetic process Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process. go-plus.json regulation of ferricrocin biosynthetic process, peptide formation|regulation of ferricrocin anabolism|regulation of ferricrocin synthesis|regulation of ferricrocin biosynthetic process, peptide modification|regulation of ferricrocin formation|regulation of ferricrocin biosynthesis http://purl.obolibrary.org/obo/GO_1900678 CHEBI:21212 biolink:ChemicalSubstance L-4'-bromophenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21212 CHEBI:59826 biolink:ChemicalSubstance progestin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59826 GO:1900675 biolink:BiologicalProcess regulation of F-9775B biosynthetic process Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process. go-plus.json regulation of F-9775B anabolism|regulation of F-9775B synthesis|regulation of F-9775B biosynthesis|regulation of F-9775B formation http://purl.obolibrary.org/obo/GO_1900675 RO:0004035 biolink:OntologyClass acts upstream of, negative effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative RO:0004035 go-plus.json http://purl.obolibrary.org/obo/RO_0004035 GO:1900674 biolink:BiologicalProcess olefin biosynthetic process The chemical reactions and pathways resulting in the formation of olefin. go-plus.json olefin anabolism|olefin synthesis|olefin formation|olefin biosynthesis http://purl.obolibrary.org/obo/GO_1900674 GO:1900677 biolink:BiologicalProcess positive regulation of F-9775B biosynthetic process Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process. go-plus.json upregulation of F-9775B anabolism|positive regulation of F-9775B biosynthesis|up regulation of F-9775B biosynthesis|up regulation of F-9775B biosynthetic process|upregulation of F-9775B synthesis|upregulation of F-9775B formation|up regulation of F-9775B anabolism|positive regulation of F-9775B anabolism|upregulation of F-9775B biosynthetic process|upregulation of F-9775B biosynthesis|up regulation of F-9775B synthesis|positive regulation of F-9775B synthesis|activation of F-9775B anabolism|up regulation of F-9775B formation|positive regulation of F-9775B formation|activation of F-9775B synthesis|up-regulation of F-9775B biosynthetic process|up-regulation of F-9775B biosynthesis|up-regulation of F-9775B anabolism|activation of F-9775B formation|activation of F-9775B biosynthetic process|up-regulation of F-9775B synthesis|activation of F-9775B biosynthesis|up-regulation of F-9775B formation http://purl.obolibrary.org/obo/GO_1900677 GO:1900676 biolink:BiologicalProcess negative regulation of F-9775B biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process. go-plus.json inhibition of F-9775B synthesis|down regulation of F-9775B anabolism|inhibition of F-9775B formation|downregulation of F-9775B biosynthetic process|downregulation of F-9775B anabolism|down regulation of F-9775B synthesis|downregulation of F-9775B biosynthesis|down regulation of F-9775B formation|downregulation of F-9775B synthesis|down regulation of F-9775B biosynthetic process|down regulation of F-9775B biosynthesis|inhibition of F-9775B biosynthetic process|downregulation of F-9775B formation|down-regulation of F-9775B anabolism|negative regulation of F-9775B anabolism|inhibition of F-9775B biosynthesis|down-regulation of F-9775B synthesis|negative regulation of F-9775B synthesis|down-regulation of F-9775B formation|negative regulation of F-9775B formation|inhibition of F-9775B anabolism|negative regulation of F-9775B biosynthesis|down-regulation of F-9775B biosynthesis|down-regulation of F-9775B biosynthetic process http://purl.obolibrary.org/obo/GO_1900676 GO:1900671 biolink:BiologicalProcess negative regulation of F-9775A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process. go-plus.json inhibition of F-9775A formation|down regulation of F-9775A anabolism|downregulation of F-9775A biosynthetic process|downregulation of F-9775A biosynthesis|down regulation of F-9775A synthesis|downregulation of F-9775A anabolism|down regulation of F-9775A biosynthetic process|down regulation of F-9775A biosynthesis|down regulation of F-9775A formation|inhibition of F-9775A biosynthetic process|downregulation of F-9775A synthesis|downregulation of F-9775A formation|inhibition of F-9775A biosynthesis|down-regulation of F-9775A anabolism|negative regulation of F-9775A anabolism|down-regulation of F-9775A synthesis|negative regulation of F-9775A synthesis|down-regulation of F-9775A formation|negative regulation of F-9775A formation|inhibition of F-9775A anabolism|down-regulation of F-9775A biosynthesis|negative regulation of F-9775A biosynthesis|down-regulation of F-9775A biosynthetic process|inhibition of F-9775A synthesis http://purl.obolibrary.org/obo/GO_1900671 RO:0004032 biolink:OntologyClass acts upstream of or within, positive effect RO:0004032 go-plus.json http://purl.obolibrary.org/obo/RO_0004032 GO:1900670 biolink:BiologicalProcess regulation of F-9775A biosynthetic process Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process. go-plus.json regulation of F-9775A anabolism|regulation of F-9775A biosynthesis|regulation of F-9775A synthesis|regulation of F-9775A formation http://purl.obolibrary.org/obo/GO_1900670 RO:0004031 biolink:OntologyClass enables subfunction Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. RO:0004031 go-plus.json http://purl.obolibrary.org/obo/RO_0004031 GO:1900673 biolink:BiologicalProcess olefin metabolic process The chemical reactions and pathways involving olefin. go-plus.json olefin metabolism http://purl.obolibrary.org/obo/GO_1900673 RO:0004034 biolink:OntologyClass acts upstream of, positive effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive RO:0004034 go-plus.json http://purl.obolibrary.org/obo/RO_0004034 GO:1900672 biolink:BiologicalProcess positive regulation of F-9775A biosynthetic process Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process. go-plus.json up regulation of F-9775A biosynthetic process|up regulation of F-9775A biosynthesis|upregulation of F-9775A synthesis|upregulation of F-9775A formation|up regulation of F-9775A anabolism|upregulation of F-9775A biosynthetic process|upregulation of F-9775A biosynthesis|positive regulation of F-9775A anabolism|up regulation of F-9775A synthesis|positive regulation of F-9775A synthesis|activation of F-9775A anabolism|up regulation of F-9775A formation|positive regulation of F-9775A formation|up-regulation of F-9775A biosynthesis|activation of F-9775A synthesis|activation of F-9775A biosynthetic process|up-regulation of F-9775A biosynthetic process|up-regulation of F-9775A anabolism|activation of F-9775A formation|activation of F-9775A biosynthesis|up-regulation of F-9775A synthesis|up-regulation of F-9775A formation|positive regulation of F-9775A biosynthesis|upregulation of F-9775A anabolism http://purl.obolibrary.org/obo/GO_1900672 RO:0004033 biolink:OntologyClass acts upstream of or within, negative effect RO:0004033 go-plus.json http://purl.obolibrary.org/obo/RO_0004033 CHEBI:35850 biolink:ChemicalSubstance sulfone go-plus.json http://purl.obolibrary.org/obo/CHEBI_35850 UBERON:0002285 biolink:AnatomicalEntity telencephalic ventricle A brain ventricle that is part of a telencephalon. In mammals and species with an evaginated telencephalon, this is one of a pair of lateral structures, one in each hemisphere go-plus.json forebrain ventricle|lateral ventricle of brain|telencephalic ventricles|tectal ventricle|telencephalic vesicle|telencephalic ventricle|telencephalon lateral ventricle|lateral ventricles|lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002285 GO:1900680 biolink:BiologicalProcess positive regulation of ferricrocin biosynthetic process Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process. go-plus.json up-regulation of ferricrocin biosynthetic process, peptide formation|positive regulation of ferricrocin biosynthesis|up regulation of ferricrocin anabolism|up regulation of ferricrocin biosynthesis|up regulation of ferricrocin biosynthetic process|positive regulation of ferricrocin anabolism|up regulation of ferricrocin synthesis|positive regulation of ferricrocin synthesis|upregulation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin formation|upregulation of ferricrocin biosynthetic process, peptide formation|activation of ferricrocin anabolism|positive regulation of ferricrocin formation|upregulation of ferricrocin biosynthesis|upregulation of ferricrocin biosynthetic process|activation of ferricrocin synthesis|up-regulation of ferricrocin anabolism|activation of ferricrocin formation|up-regulation of ferricrocin biosynthetic process, peptide modification|up-regulation of ferricrocin synthesis|up regulation of ferricrocin biosynthetic process, peptide formation|up-regulation of ferricrocin biosynthetic process|positive regulation of ferricrocin biosynthetic process, peptide formation|up-regulation of ferricrocin biosynthesis|up-regulation of ferricrocin formation|activation of ferricrocin biosynthetic process|activation of ferricrocin biosynthetic process, peptide modification|upregulation of ferricrocin anabolism|activation of ferricrocin biosynthetic process, peptide formation|activation of ferricrocin biosynthesis|upregulation of ferricrocin synthesis|positive regulation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin biosynthetic process, peptide modification|upregulation of ferricrocin formation http://purl.obolibrary.org/obo/GO_1900680 CHEBI:35856 biolink:ChemicalSubstance lipoxygenase inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35856 UBERON:0002280 biolink:AnatomicalEntity otolith Acellular structure composed of calcium carbonate located in the otolith organ. go-plus.json immature otolith|statoconium|statoconia|otoliths|otoconial crystal|otoconia|otoconium|statolith|immature otoliths http://purl.obolibrary.org/obo/UBERON_0002280 CHEBI:59825 biolink:ChemicalSubstance CMP-3-deoxy-alpha-D-manno-octulosonate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59825 chebi_ph7_3 GO:0071569 biolink:BiologicalProcess protein ufmylation Covalent attachment of the ubiquitin-like protein UFM1 to another protein. go-plus.json http://purl.obolibrary.org/obo/GO_0071569 CHEBI:21217 biolink:ChemicalSubstance L-alaninamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_21217 GO:0071568 biolink:MolecularActivity UFM1 transferase activity Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages. go-plus.json http://purl.obolibrary.org/obo/GO_0071568 GO:0071567 biolink:MolecularActivity UFM1 hydrolase activity Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates. go-plus.json http://purl.obolibrary.org/obo/GO_0071567 GO:0071566 biolink:MolecularActivity UFM1 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond. go-plus.json http://purl.obolibrary.org/obo/GO_0071566 GO:0071565 biolink:CellularComponent nBAF complex A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. go-plus.json http://purl.obolibrary.org/obo/GO_0071565 GO:0071564 biolink:CellularComponent npBAF complex A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. go-plus.json http://purl.obolibrary.org/obo/GO_0071564 UBERON:0002286 biolink:AnatomicalEntity third ventricle Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct. (Maryann Martone) go-plus.json ventriculus diencephali|ventriculus tertius cerebri|diencephalic ventricle|3rd ventricle|diencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0002286 GO:0071563 biolink:CellularComponent Myo2p-Vac17p-Vac8p transport complex A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p. go-plus.json http://purl.obolibrary.org/obo/GO_0071563 UBERON:0002288 biolink:AnatomicalEntity choroid plexus of third ventricle Part of choroid plexus contained in the third ventricle go-plus.json chorioid plexus of cerebral hemisphere of third ventricle|choroid plexus third ventricle|diencephalic choroid plexus|third ventricle choroid plexus|third ventricle chorioid plexus of cerebral hemisphere|3rd ventricle choroid plexus|chorioid plexus of third ventricle http://purl.obolibrary.org/obo/UBERON_0002288 GO:0071562 biolink:BiologicalProcess nucleus-vacuole junction assembly The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. go-plus.json NVJ formation|NV junction formation|nucleus-vacuole junction formation|NV junction assembly|NVJ assembly http://purl.obolibrary.org/obo/GO_0071562 GO:0071550 biolink:BiologicalProcess death-inducing signaling complex assembly A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway. go-plus.json DD-mediated complex assembly|DISC assembly|death domain-mediated complex assembly involved in extrinsic apoptotic pathway|death domain-mediated complex assembly|death-inducing signaling complex formation|death-inducing signalling complex assembly|DISC formation http://purl.obolibrary.org/obo/GO_0071550 GO:1900689 biolink:BiologicalProcess regulation of gliotoxin biosynthetic process Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process. go-plus.json regulation of gliotoxin synthesis|regulation of gliotoxin formation|regulation of gliotoxin biosynthesis|regulation of gliotoxin anabolism http://purl.obolibrary.org/obo/GO_1900689 CHEBI:59815 biolink:ChemicalSubstance 2,3,5,6-tetrachlorophenolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59815 chebi_ph7_3 GO:1900686 biolink:BiologicalProcess regulation of gerfelin biosynthetic process Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process. go-plus.json regulation of gerfelin anabolism|regulation of gerfelin synthesis|regulation of gerfelin formation|regulation of gerfelin biosynthesis http://purl.obolibrary.org/obo/GO_1900686 GO:1900685 biolink:BiologicalProcess positive regulation of fumonisin biosynthetic process Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process. go-plus.json upregulation of fumonisin anabolism|upregulation of fumonisin synthesis|upregulation of fumonisin formation|upregulation of fumonisin biosynthesis|upregulation of fumonisin biosynthetic process|up regulation of fumonisin anabolism|positive regulation of fumonisin anabolism|up regulation of fumonisin synthesis|positive regulation of fumonisin synthesis|up regulation of fumonisin formation|up-regulation of fumonisin biosynthesis|activation of fumonisin anabolism|up-regulation of fumonisin biosynthetic process|activation of fumonisin biosynthetic process|positive regulation of fumonisin formation|activation of fumonisin synthesis|up-regulation of fumonisin anabolism|activation of fumonisin biosynthesis|activation of fumonisin formation|up-regulation of fumonisin synthesis|positive regulation of fumonisin biosynthesis|up-regulation of fumonisin formation|up regulation of fumonisin biosynthesis|up regulation of fumonisin biosynthetic process http://purl.obolibrary.org/obo/GO_1900685 CHEBI:35868 biolink:ChemicalSubstance hydroxy monocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35868 GO:1900688 biolink:BiologicalProcess positive regulation of gerfelin biosynthetic process Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process. go-plus.json up-regulation of gerfelin synthesis|up regulation of gerfelin biosynthetic process|up regulation of gerfelin biosynthesis|activation of gerfelin anabolism|activation of gerfelin biosynthetic process|up-regulation of gerfelin formation|positive regulation of gerfelin biosynthesis|activation of gerfelin synthesis|positive regulation of gerfelin anabolism|activation of gerfelin biosynthesis|activation of gerfelin formation|up regulation of gerfelin anabolism|positive regulation of gerfelin synthesis|up regulation of gerfelin synthesis|positive regulation of gerfelin formation|up-regulation of gerfelin biosynthesis|up-regulation of gerfelin biosynthetic process|up regulation of gerfelin formation|upregulation of gerfelin anabolism|upregulation of gerfelin biosynthesis|upregulation of gerfelin synthesis|upregulation of gerfelin biosynthetic process|upregulation of gerfelin formation|up-regulation of gerfelin anabolism http://purl.obolibrary.org/obo/GO_1900688 GO:1900687 biolink:BiologicalProcess negative regulation of gerfelin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process. go-plus.json down-regulation of gerfelin anabolism|negative regulation of gerfelin anabolism|down-regulation of gerfelin biosynthesis|down-regulation of gerfelin biosynthetic process|down-regulation of gerfelin synthesis|negative regulation of gerfelin synthesis|negative regulation of gerfelin biosynthesis|down-regulation of gerfelin formation|negative regulation of gerfelin formation|downregulation of gerfelin anabolism|inhibition of gerfelin biosynthetic process|downregulation of gerfelin synthesis|down regulation of gerfelin anabolism|inhibition of gerfelin biosynthesis|downregulation of gerfelin formation|down regulation of gerfelin synthesis|inhibition of gerfelin anabolism|down regulation of gerfelin formation|down regulation of gerfelin biosynthesis|down regulation of gerfelin biosynthetic process|inhibition of gerfelin synthesis|inhibition of gerfelin formation|downregulation of gerfelin biosynthetic process|downregulation of gerfelin biosynthesis http://purl.obolibrary.org/obo/GO_1900687 GO:1900682 biolink:BiologicalProcess octadecene biosynthetic process The chemical reactions and pathways resulting in the formation of octadecene. go-plus.json octadecene anabolism|octadecene biosynthesis|octadecene synthesis|octadecene formation|1-octadecene biosynthetic process http://purl.obolibrary.org/obo/GO_1900682 GO:1900681 biolink:BiologicalProcess octadecene metabolic process The chemical reactions and pathways involving octadecene. go-plus.json octadecene metabolism http://purl.obolibrary.org/obo/GO_1900681 GO:1900684 biolink:BiologicalProcess negative regulation of fumonisin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process. go-plus.json inhibition of fumonisin synthesis|downregulation of fumonisin biosynthesis|downregulation of fumonisin biosynthetic process|inhibition of fumonisin formation|down regulation of fumonisin anabolism|down regulation of fumonisin biosynthesis|down regulation of fumonisin biosynthetic process|inhibition of fumonisin biosynthetic process|downregulation of fumonisin anabolism|down regulation of fumonisin synthesis|down regulation of fumonisin formation|downregulation of fumonisin synthesis|inhibition of fumonisin biosynthesis|downregulation of fumonisin formation|down-regulation of fumonisin anabolism|negative regulation of fumonisin anabolism|down-regulation of fumonisin synthesis|negative regulation of fumonisin synthesis|down-regulation of fumonisin formation|negative regulation of fumonisin formation|down-regulation of fumonisin biosynthetic process|down-regulation of fumonisin biosynthesis|negative regulation of fumonisin biosynthesis|inhibition of fumonisin anabolism http://purl.obolibrary.org/obo/GO_1900684 GO:1900683 biolink:BiologicalProcess regulation of fumonisin biosynthetic process Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process. go-plus.json regulation of fumonisin biosynthesis|regulation of fumonisin anabolism|regulation of fumonisin synthesis|regulation of fumonisin formation http://purl.obolibrary.org/obo/GO_1900683 UBERON:0002272 biolink:AnatomicalEntity medial zone of hypothalamus go-plus.json medial zone of the hypothalamus|hypothalamic medial zone behavioral control column|zona medialis hypothalamicae|hypothalamus medial zone http://purl.obolibrary.org/obo/UBERON_0002272 GO:1900691 biolink:BiologicalProcess positive regulation of gliotoxin biosynthetic process Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process. go-plus.json up-regulation of gliotoxin formation|upregulation of gliotoxin biosynthetic process|upregulation of gliotoxin biosynthesis|upregulation of gliotoxin anabolism|upregulation of gliotoxin synthesis|activation of gliotoxin biosynthetic process|up-regulation of gliotoxin biosynthetic process|upregulation of gliotoxin formation|up-regulation of gliotoxin biosynthesis|up regulation of gliotoxin anabolism|positive regulation of gliotoxin anabolism|activation of gliotoxin biosynthesis|up regulation of gliotoxin synthesis|positive regulation of gliotoxin synthesis|activation of gliotoxin anabolism|up regulation of gliotoxin formation|positive regulation of gliotoxin biosynthesis|positive regulation of gliotoxin formation|up regulation of gliotoxin biosynthetic process|up regulation of gliotoxin biosynthesis|activation of gliotoxin synthesis|up-regulation of gliotoxin anabolism|activation of gliotoxin formation|up-regulation of gliotoxin synthesis http://purl.obolibrary.org/obo/GO_1900691 GO:1900690 biolink:BiologicalProcess negative regulation of gliotoxin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process. go-plus.json inhibition of gliotoxin synthesis|inhibition of gliotoxin biosynthesis|down regulation of gliotoxin anabolism|inhibition of gliotoxin formation|downregulation of gliotoxin anabolism|down regulation of gliotoxin synthesis|down regulation of gliotoxin formation|downregulation of gliotoxin synthesis|negative regulation of gliotoxin biosynthesis|downregulation of gliotoxin formation|down-regulation of gliotoxin biosynthetic process|down-regulation of gliotoxin biosynthesis|down-regulation of gliotoxin anabolism|negative regulation of gliotoxin anabolism|down-regulation of gliotoxin synthesis|negative regulation of gliotoxin synthesis|downregulation of gliotoxin biosynthetic process|down-regulation of gliotoxin formation|negative regulation of gliotoxin formation|downregulation of gliotoxin biosynthesis|down regulation of gliotoxin biosynthetic process|down regulation of gliotoxin biosynthesis|inhibition of gliotoxin anabolism|inhibition of gliotoxin biosynthetic process http://purl.obolibrary.org/obo/GO_1900690 CHEBI:35862 biolink:ChemicalSubstance bacitracin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_35862 CHEBI:35865 biolink:ChemicalSubstance 5alpha-cholest-7-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35865 chebi_ph7_3 GO:0071559 biolink:BiologicalProcess response to transforming growth factor beta Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. go-plus.json response to TGF-beta stimulus|response to TGFbeta stimulus|response to transforming growth factor beta stimulus http://purl.obolibrary.org/obo/GO_0071559 GO:0071558 biolink:MolecularActivity histone H3-tri/di-methyl-lysine-27 demethylase activity Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. Reactome:R-HSA-5617887|EC:1.14.11.68|Reactome:R-HSA-3222593|Reactome:R-HSA-5617431|RHEA:60224 go-plus.json histone H3K27me2 demethylase activity|histone H3K27me3 demethylase activity|histone demethylase activity (H3-K27 specific) http://purl.obolibrary.org/obo/GO_0071558 CHEBI:59814 biolink:ChemicalSubstance L-alpha-amino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59814 GO:0071557 biolink:BiologicalProcess histone H3-K27 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone. go-plus.json H3K27 demethylation http://purl.obolibrary.org/obo/GO_0071557 GO:0071556 biolink:CellularComponent integral component of lumenal side of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane. go-plus.json integral to lumenal side of endoplasmic reticulum membrane|integral to lumenal leaflet of endoplasmic reticulum membrane|integral to ER membrane, lumenal side|integral to lumenal side of ER membrane http://purl.obolibrary.org/obo/GO_0071556 GO:0071555 biolink:BiologicalProcess cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. go-plus.json cell wall organization at cellular level|cellular cell wall organization|cell wall organization and biogenesis|cell wall organisation|cell wall organisation in other organism|cell wall organization in other organism|cellular cell wall organisation http://purl.obolibrary.org/obo/GO_0071555 goslim_candida|goslim_pir GO:0071554 biolink:BiologicalProcess cell wall organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall. go-plus.json cellular cell wall organisation or biogenesis|cell wall organization or biogenesis at cellular level|cellular cell wall organization or biogenesis|cell wall organisation or biogenesis http://purl.obolibrary.org/obo/GO_0071554 goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast GO:0071553 biolink:MolecularActivity G protein-coupled pyrimidinergic nucleotide receptor activity Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. go-plus.json pyrimidinergic nucleotide receptor activity, G-protein coupled|pyrimidinergic nucleotide receptor activity, G protein coupled|G-protein coupled pyrimidinergic nucleotide receptor activity|G protein coupled pyrimidinergic nucleotide receptor activity http://purl.obolibrary.org/obo/GO_0071553 UBERON:0002275 biolink:AnatomicalEntity reticular formation A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 ). go-plus.json brainstem reticular formation|reticular formation of the brainstem|reticular formation (classical)|brain stem reticular formation http://purl.obolibrary.org/obo/UBERON_0002275 GO:0071552 biolink:BiologicalProcess obsolete RIP homotypic interaction motif-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction. go-plus.json RHIM-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071552 GO:0071551 biolink:MolecularActivity RIP homotypic interaction motif binding Binding to a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases. go-plus.json RHIM binding http://purl.obolibrary.org/obo/GO_0071551 GO:0071583 biolink:BiologicalProcess negative regulation of zinc ion transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other. go-plus.json negative regulation of zinc ion membrane transport http://purl.obolibrary.org/obo/GO_0071583 GO:0071582 biolink:BiologicalProcess negative regulation of zinc ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0071582 CHEBI:59809 biolink:ChemicalSubstance docetaxel trihydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59809 GO:0071581 biolink:BiologicalProcess regulation of zinc ion transmembrane import Any process that modulates the frequency, rate or extent of zinc ion import. go-plus.json http://purl.obolibrary.org/obo/GO_0071581 GO:0071580 biolink:BiologicalProcess regulation of zinc ion transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other. go-plus.json regulation of zinc ion membrane transport http://purl.obolibrary.org/obo/GO_0071580 CHEBI:59807 biolink:ChemicalSubstance (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59807 chebi_ph7_3 CHEBI:59806 biolink:ChemicalSubstance (S)-nicotinium(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59806 chebi_ph7_3 GO:1900697 biolink:BiologicalProcess positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process. go-plus.json upregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|upregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|up-regulation of N',N'',N'''-triacetylfusarinine C synthesis|up-regulation of N',N'',N'''-triacetylfusarinine C formation|upregulation of N',N'',N'''-triacetylfusarinine C anabolism|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C biosynthetic process|upregulation of N',N'',N'''-triacetylfusarinine C synthesis|upregulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C biosynthesis|up regulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|up regulation of N',N'',N'''-triacetylfusarinine C synthesis|positive regulation of N',N'',N'''-triacetylfusarinine C synthesis|up regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C anabolism|up regulation of N',N'',N'''-triacetylfusarinine C formation|positive regulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C synthesis|up-regulation of N',N'',N'''-triacetylfusarinine C anabolism|activation of N',N'',N'''-triacetylfusarinine C formation http://purl.obolibrary.org/obo/GO_1900697 GO:1900696 biolink:BiologicalProcess negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process. go-plus.json inhibition of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C synthesis|down regulation of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C synthesis|downregulation of N',N'',N'''-triacetylfusarinine C anabolism|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|negative regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|down regulation of N',N'',N'''-triacetylfusarinine C formation|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|downregulation of N',N'',N'''-triacetylfusarinine C synthesis|downregulation of N',N'',N'''-triacetylfusarinine C formation|down-regulation of N',N'',N'''-triacetylfusarinine C anabolism|negative regulation of N',N'',N'''-triacetylfusarinine C anabolism|downregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|downregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|down-regulation of N',N'',N'''-triacetylfusarinine C synthesis|negative regulation of N',N'',N'''-triacetylfusarinine C synthesis|down-regulation of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|negative regulation of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C biosynthetic process http://purl.obolibrary.org/obo/GO_1900696 GO:1900699 biolink:BiologicalProcess negative regulation of o-orsellinic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process. go-plus.json down-regulation of o-orsellinic acid anabolism|negative regulation of o-orsellinic acid anabolism|down-regulation of o-orsellinic acid synthesis|negative regulation of o-orsellinic acid synthesis|negative regulation of o-orsellinic acid biosynthesis|down-regulation of o-orsellinic acid biosynthesis|down-regulation of o-orsellinic acid biosynthetic process|down-regulation of o-orsellinic acid formation|negative regulation of o-orsellinic acid formation|inhibition of o-orsellinic acid anabolism|downregulation of o-orsellinic acid biosynthesis|downregulation of o-orsellinic acid biosynthetic process|inhibition of o-orsellinic acid synthesis|down regulation of o-orsellinic acid anabolism|down regulation of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid biosynthesis|inhibition of o-orsellinic acid formation|inhibition of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid synthesis|downregulation of o-orsellinic acid anabolism|inhibition of o-orsellinic acid biosynthesis|down regulation of o-orsellinic acid formation|downregulation of o-orsellinic acid synthesis|downregulation of o-orsellinic acid formation http://purl.obolibrary.org/obo/GO_1900699 GO:1900698 biolink:BiologicalProcess regulation of o-orsellinic acid biosynthetic process Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process. go-plus.json regulation of o-orsellinic acid biosynthesis|regulation of o-orsellinic acid anabolism|regulation of o-orsellinic acid synthesis|regulation of o-orsellinic acid formation http://purl.obolibrary.org/obo/GO_1900698 GO:1900693 biolink:BiologicalProcess negative regulation of (+)-kotanin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process. go-plus.json inhibition of (+)-kotanin formation|down regulation of (+)-kotanin biosynthetic process|down regulation of (+)-kotanin anabolism|down regulation of (+)-kotanin biosynthesis|inhibition of (+)-kotanin biosynthetic process|downregulation of (+)-kotanin anabolism|down regulation of (+)-kotanin synthesis|inhibition of (+)-kotanin biosynthesis|down regulation of (+)-kotanin formation|downregulation of (+)-kotanin synthesis|downregulation of (+)-kotanin formation|down-regulation of (+)-kotanin anabolism|negative regulation of (+)-kotanin anabolism|down-regulation of (+)-kotanin synthesis|negative regulation of (+)-kotanin synthesis|negative regulation of (+)-kotanin biosynthesis|down-regulation of (+)-kotanin biosynthetic process|down-regulation of (+)-kotanin biosynthesis|down-regulation of (+)-kotanin formation|negative regulation of (+)-kotanin formation|inhibition of (+)-kotanin anabolism|downregulation of (+)-kotanin biosynthesis|downregulation of (+)-kotanin biosynthetic process|inhibition of (+)-kotanin synthesis http://purl.obolibrary.org/obo/GO_1900693 GO:1900692 biolink:BiologicalProcess regulation of (+)-kotanin biosynthetic process Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process. go-plus.json regulation of (+)-kotanin anabolism|regulation of (+)-kotanin synthesis|regulation of (+)-kotanin formation|regulation of (+)-kotanin biosynthesis http://purl.obolibrary.org/obo/GO_1900692 GO:1900695 biolink:BiologicalProcess regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process. go-plus.json regulation of N',N'',N'''-triacetylfusarinine C anabolism|regulation of N',N'',N'''-triacetylfusarinine C synthesis|regulation of N',N'',N'''-triacetylfusarinine C formation|regulation of N',N'',N'''-triacetylfusarinine C biosynthesis http://purl.obolibrary.org/obo/GO_1900695 GO:1900694 biolink:BiologicalProcess positive regulation of (+)-kotanin biosynthetic process Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process. go-plus.json upregulation of (+)-kotanin synthesis|upregulation of (+)-kotanin biosynthetic process|upregulation of (+)-kotanin biosynthesis|upregulation of (+)-kotanin formation|up regulation of (+)-kotanin anabolism|positive regulation of (+)-kotanin anabolism|up regulation of (+)-kotanin synthesis|up-regulation of (+)-kotanin biosynthetic process|up-regulation of (+)-kotanin biosynthesis|activation of (+)-kotanin biosynthetic process|positive regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin formation|activation of (+)-kotanin anabolism|positive regulation of (+)-kotanin formation|activation of (+)-kotanin synthesis|activation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin anabolism|activation of (+)-kotanin formation|positive regulation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin biosynthetic process|up regulation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin formation|upregulation of (+)-kotanin anabolism http://purl.obolibrary.org/obo/GO_1900694 UBERON:0002261 biolink:AnatomicalEntity dorsal root of spinal cord The dorsal roots contain afferent sensory axons. The dorsal roots of each side continue outwards, along the way forming a dorsal root ganglion (also called a spinal ganglion). go-plus.json dorsal roots|posterior root of spinal nerve|sensory root of spinal nerve|radix posterior nervi spinalis|dorsal spinal nerve root|radix sensoria (nervus spinalis)|radix posterior|radix dorsalis|radix posterior (nervus spinalis)|root sensoria nervi spinalis|root dorsali nervi spinalis|sensory spinal root|dorsal spinal root|dorsal root|dorsal root of spinal nerve http://purl.obolibrary.org/obo/UBERON_0002261 UBERON:0002263 biolink:AnatomicalEntity lentiform nucleus The lentiform nucleus or lenticular nucleus comprises the putamen and the globus pallidus within the basal ganglia. It is a large, cone-shaped mass of gray matter just lateral to the internal capsule. [WP,unvetted]. go-plus.json nucleus lentiformis|nucleus lenticularis|lenticular nucleus|nucleus lentiformis http://purl.obolibrary.org/obo/UBERON_0002263 RO:0004007 biolink:OntologyClass has primary input or output p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. RO:0004007 go-plus.json http://purl.obolibrary.org/obo/RO_0004007 RO:0004009 biolink:OntologyClass has primary input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. RO:0004009 go-plus.json http://purl.obolibrary.org/obo/RO_0004009 RO:0004008 biolink:OntologyClass has primary output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. RO:0004008 go-plus.json http://purl.obolibrary.org/obo/RO_0004008 UBERON:0002268 biolink:AnatomicalEntity olfactory organ An organ that houses olfactory neurons and is responsible for the sense of smell. Examples include the vertebrate nose and the Drosophila dorsal organ. go-plus.json olfactory neuroepithelium|primary olfactory organ|olfactory organ|main olfactory organ|olfactory sensory organ|organum olfactorium|organ olfactus|olfactory sense organ http://purl.obolibrary.org/obo/UBERON_0002268 GO:0071589 biolink:BiologicalProcess pyridine nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose. go-plus.json pyridine nucleoside anabolism|pyridine nucleoside synthesis|pyridine nucleoside formation|pyridine nucleoside biosynthesis http://purl.obolibrary.org/obo/GO_0071589 GO:0071588 biolink:BiologicalProcess hydrogen peroxide mediated signaling pathway A series of molecular signals mediated by the detection of hydrogen peroxide (H2O2). go-plus.json H2O2 mediated signaling pathway|hydrogen peroxide mediated signalling pathway http://purl.obolibrary.org/obo/GO_0071588 UBERON:0002265 biolink:AnatomicalEntity olfactory tract White matter tract that contains projections from the olfactory bulb to other parts of the brain go-plus.json tractus olfactorius|olfactory stalk|tractus olfactorium|olfactory peduncle|pedunclulus olfactorius http://purl.obolibrary.org/obo/UBERON_0002265 GO:0071587 biolink:BiologicalProcess CAAX-box protein modification The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0071587 GO:0071586 biolink:BiologicalProcess CAAX-box protein processing The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0071586 UBERON:0002264 biolink:AnatomicalEntity olfactory bulb A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes)[BTO]. go-plus.json bulbus olfactorius (Morgagni)|bulbus olfactorius|bulbus olfactorius|olfactory lobe|olfactory lobe (Barr & Kiernan) http://purl.obolibrary.org/obo/UBERON_0002264 GO:0071585 biolink:BiologicalProcess detoxification of cadmium ion Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion. go-plus.json http://purl.obolibrary.org/obo/GO_0071585 GO:0071584 biolink:BiologicalProcess negative regulation of zinc ion transmembrane import Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import. go-plus.json http://purl.obolibrary.org/obo/GO_0071584 GO:0071572 biolink:BiologicalProcess histone H3-K56 deacetylation The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone. go-plus.json http://purl.obolibrary.org/obo/GO_0071572 GO:0071571 biolink:BiologicalProcess obsolete LRR domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction. go-plus.json leucine-rich repeat domain-mediated complex assembly http://purl.obolibrary.org/obo/GO_0071571 GO:0071570 biolink:BiologicalProcess cement gland development The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed. go-plus.json http://purl.obolibrary.org/obo/GO_0071570 CHEBI:21203 biolink:ChemicalSubstance L-2-aminohexanoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21203 CHEBI:11893 biolink:ChemicalSubstance 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11893 chebi_ph7_3 CHEBI:11892 biolink:ChemicalSubstance N-carbamoyl-beta-alaninate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11892 chebi_ph7_3 CHEBI:35842 biolink:ChemicalSubstance antirheumatic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35842 UBERON:0002258 biolink:AnatomicalEntity dorsal funiculus of spinal cord the white substance of the spinal cord lying on either side between the posterior median sulcus and the dorsal root. go-plus.json posterior funiculus of spinal cord|posterior white column of spinal cord|funiculus posterior medullae spinalis|funiculus dorsalis|dorsal white column of spinal cord|posterior funiculus|dorsal funiculus|dorsal funiculus of spinal cord http://purl.obolibrary.org/obo/UBERON_0002258 UBERON:0002257 biolink:AnatomicalEntity ventral horn of spinal cord The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]. go-plus.json ventral region of spinal cord|spinal cord anterior horn|columna grisea anterior medullae spinalis|anterior grey column of spinal cord|ventral horn of the spinal cord|ventral spinal cord|anterior column|anterior column of the spinal cord|anterior gray horn of spinal cord|ventral gray column of spinal cord|ventral horn spinal cord|ventral grey horn|anterior horn|cornu anterius medullae spinalis|spinal cord ventral horn|ventral grey column of spinal cord|anterior horn (spinal cord)|ventral horns spinal cord|ventral gray matter of spinal cord|anterior gray column of spinal cord http://purl.obolibrary.org/obo/UBERON_0002257 GO:0071579 biolink:BiologicalProcess regulation of zinc ion transport Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0071579 GO:0071578 biolink:BiologicalProcess zinc ion import across plasma membrane The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json zinc import|zinc uptake|zinc ion transmembrane import|high-affinity zinc II ion transmembrane import|low-affinity zinc II ion transport|zinc II ion plasma membrane import|high-affinity zinc II ion transport|zinc II ion transmembrane import http://purl.obolibrary.org/obo/GO_0071578 CHEBI:21208 biolink:ChemicalSubstance L-3'-bromophenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21208 UBERON:0002259 biolink:AnatomicalEntity corpora quadrigemina Either of the two pairs of colliculi on the dorsal surface of the midbrain composed of white matter externally and gray matter within, the superior pair containing correlation centers for optic reflexes and the inferior pair containing correlation centers for auditory reflexes[BTO]. go-plus.json set of colliculi|corpora quadrigemina|colliculi|quadrigeminal body http://purl.obolibrary.org/obo/UBERON_0002259 GO:0071577 biolink:BiologicalProcess zinc ion transmembrane transport A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json zinc ion membrane transport|zinc II ion transmembrane transport|zinc transmembrane transport http://purl.obolibrary.org/obo/GO_0071577 GO:0071576 biolink:MolecularActivity tetrahydrodictyopterin binding Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one. go-plus.json DH4 binding|D-threo-tetrahydrobiopterin http://purl.obolibrary.org/obo/GO_0071576 GO:0071575 biolink:CellularComponent integral component of external side of plasma membrane The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane. go-plus.json integral to external leaflet of plasma membrane|integral to external side of plasma membrane http://purl.obolibrary.org/obo/GO_0071575 UBERON:0002256 biolink:AnatomicalEntity dorsal horn of spinal cord The pronounced, dorsolaterally oriented ridge of grey matter in each lateral half of the spinal cord[MP]. the dorsal (more towards the back) grey matter of the spinal cord. It receives several types of sensory information from the body, including light touch, proprioception, and vibration. This information is sent from receptors of the skin, bones, and joints through sensory neurons whose cell bodies lie in the dorsal root ganglion[WP]. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input[GO]. go-plus.json cornu dorsale|dorsal grey column of spinal cord|dorsal gray horn|posterior gray column of spinal cord|dorsal region of mature spinal cord|spinal cord posterior horn|dorsal gray matter of spinal cord|posterior grey column of spinal cord|cornu posterius medullae spinalis|spinal cord dorsal horns|dorsal grey horn|columna grisea posterior medullae spinalis|posterior gray horn of spinal cord|dorsal horn of the spinal cord|posterior horn of spinal cord|dorsal horn|dorsal region of spinal cord|dorsal gray column of spinal cord|spinal cord dorsal horn|dorsal horn spinal cord|dorsal spinal cord http://purl.obolibrary.org/obo/UBERON_0002256 GO:0071574 biolink:BiologicalProcess protein localization to medial cortex A process in which a protein is transported to, or maintained in, the medial cortex. go-plus.json protein localisation to medial cortex http://purl.obolibrary.org/obo/GO_0071574 GO:0071573 biolink:BiologicalProcess shelterin complex assembly The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. go-plus.json telosome assembly|Pot1-Tpz1 complex assembly|shelterin complex formation|Pot1 complex assembly http://purl.obolibrary.org/obo/GO_0071573 GO:0007119 biolink:BiologicalProcess budding cell isotropic bud growth Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding. go-plus.json isotropic bud growth http://purl.obolibrary.org/obo/GO_0007119 GO:0007118 biolink:BiologicalProcess budding cell apical bud growth Growth at the tip of a bud, in a cell that reproduces by budding. go-plus.json apical bud growth http://purl.obolibrary.org/obo/GO_0007118 GO:0007117 biolink:BiologicalProcess budding cell bud growth The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. go-plus.json bud growth http://purl.obolibrary.org/obo/GO_0007117 GO:0007116 biolink:BiologicalProcess regulation of cell budding Any process that modulates the frequency, rate or extent of the formation and growth of cell buds. go-plus.json regulation of budding http://purl.obolibrary.org/obo/GO_0007116 GO:0007115 biolink:BiologicalProcess obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces) OBSOLETE. (Was not defined before being made obsolete). go-plus.json bud site selection/establishment of cell polarity (sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007115 GO:0046723 biolink:BiologicalProcess malic acid secretion The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue. go-plus.json malate secretion|hydroxysuccinic acid secretion http://purl.obolibrary.org/obo/GO_0046723 GO:0007114 biolink:BiologicalProcess cell budding A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell. go-plus.json budding http://purl.obolibrary.org/obo/GO_0007114 goslim_yeast|goslim_candida GO:0046722 biolink:BiologicalProcess lactic acid secretion The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue. go-plus.json lactate secretion http://purl.obolibrary.org/obo/GO_0046722 GO:0007113 biolink:BiologicalProcess endomitotic cell cycle A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell. Wikipedia:Mitosis#Endomitosis go-plus.json endomitosis http://purl.obolibrary.org/obo/GO_0007113 GO:0046721 biolink:BiologicalProcess formic acid secretion The controlled release of formic acid, HCOOH, by a cell or a tissue. go-plus.json formate secretion http://purl.obolibrary.org/obo/GO_0046721 CHEBI:84789 biolink:ChemicalSubstance 1-palmitoyl-2-[(9Z,12Z,15Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84789 chebi_ph7_3 GO:0007112 biolink:BiologicalProcess male meiosis cytokinesis A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells. go-plus.json cytokinesis involved in male meiotic cell cycle|cytokinesis after male meiosis http://purl.obolibrary.org/obo/GO_0007112 GO:0046720 biolink:BiologicalProcess citric acid secretion The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue. go-plus.json citrate secretion http://purl.obolibrary.org/obo/GO_0046720 CHEBI:84788 biolink:ChemicalSubstance trans,trans-2,4-hexadienoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84788 chebi_ph7_3 GO:0007111 biolink:BiologicalProcess meiosis II cytokinesis A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells. go-plus.json cytokinesis after meiosis II http://purl.obolibrary.org/obo/GO_0007111 GO:0007110 biolink:BiologicalProcess meiosis I cytokinesis A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells. go-plus.json cytokinesis after meiosis I http://purl.obolibrary.org/obo/GO_0007110 CHEBI:84786 biolink:ChemicalSubstance 1-palmitoyl-2-[(6Z,9Z,12Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84786 chebi_ph7_3 GO:0046729 biolink:CellularComponent viral procapsid A stable empty viral capsid produced during the assembly of viruses. go-plus.json http://purl.obolibrary.org/obo/GO_0046729 GO:0046728 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046728 GO:0046727 biolink:CellularComponent capsomere Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses. Wikipedia:Capsomere go-plus.json capsomer http://purl.obolibrary.org/obo/GO_0046727 GO:0046726 biolink:BiologicalProcess positive regulation by virus of viral protein levels in host cell Any process where the infecting virus increases the levels of viral proteins in a cell. go-plus.json stimulation of viral protein levels in host cell|positive regulation of viral protein levels|up-regulation of viral protein levels in host cell|upregulation of viral protein levels in host cell|up regulation of viral protein levels in host cell|activation of viral protein levels in host cell http://purl.obolibrary.org/obo/GO_0046726 GO:0046725 biolink:BiologicalProcess negative regulation by virus of viral protein levels in host cell Any process where the infecting virus reduces the levels of viral proteins in a cell. go-plus.json negative regulation of viral protein levels|down-regulation of viral protein levels in host cell|inhibition of viral protein levels in host cell|down regulation of viral protein levels in host cell|downregulation of viral protein levels in host cell http://purl.obolibrary.org/obo/GO_0046725 GO:0046724 biolink:BiologicalProcess oxalic acid secretion The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue. go-plus.json oxalate secretion http://purl.obolibrary.org/obo/GO_0046724 GO:0007129 biolink:BiologicalProcess homologous chromosome pairing at meiosis The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete. Wikipedia:Synapsis go-plus.json chromosomal synapsis|homologous chromosome pairing at meiosis|chromosomal pairing|synapsis http://purl.obolibrary.org/obo/GO_0007129 GO:0007128 biolink:BiologicalProcess meiotic prophase I The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0007128 gocheck_do_not_annotate GO:0007127 biolink:BiologicalProcess meiosis I The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei. Wikipedia:Meiosis#Meiosis_I go-plus.json meiosis I nuclear division http://purl.obolibrary.org/obo/GO_0007127 GO:0007126 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007126 GO:0046734 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046734 GO:0046733 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046733 GO:0007125 biolink:BiologicalProcess obsolete invasive growth OBSOLETE. (Was not defined before being made obsolete). go-plus.json invasive growth http://purl.obolibrary.org/obo/GO_0007125 GO:0046732 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046732 GO:0007124 biolink:BiologicalProcess pseudohyphal growth The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0007124 goslim_yeast|goslim_candida GO:0046731 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046731 GO:0007123 biolink:BiologicalProcess obsolete bud scar accumulation OBSOLETE. (Was not defined before being made obsolete). go-plus.json bud scar accumulation http://purl.obolibrary.org/obo/GO_0007123 GO:0046730 biolink:BiologicalProcess induction by virus of host immune response The induction by a virus of an immune response in the host organism. go-plus.json passive induction of host innate immune response by virus|passive viral induction of innate immune response in host|passive induction of host cell-mediated immune response by virus|passive viral activation of humoral immune response in host|passive viral induction of host immune response|passive viral induction of cell-mediated immune response in host|passive induction of host immune response by virus|passive induction of innate immune response in host by virus|passive viral activation of innate immune response in host|passive activation of host immune response by virus|active viral induction of host immune response|passive induction of humoral immune response in host by virus|active induction of host immune response by virus|passive viral induction of humoral immune response in host|passive induction of host humoral immune response by virus|passive viral activation of cell-mediated immune response in host|passive induction of cell-mediated immune response in host by virus|activation of host immune response by virus http://purl.obolibrary.org/obo/GO_0046730 GO:0007122 biolink:BiologicalProcess obsolete loss of asymmetric budding OBSOLETE. (Was not defined before being made obsolete). go-plus.json loss of asymmetric budding http://purl.obolibrary.org/obo/GO_0007122 OBO:GOCHE_38632 biolink:OntologyClass substance with membrane transport modulator role go-plus.json http://purl.obolibrary.org/obo/GOCHE_38632 3_STAR GO:0007121 biolink:BiologicalProcess bipolar cellular bud site selection The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell. go-plus.json polar budding|bipolar budding|bipolar bud site selection http://purl.obolibrary.org/obo/GO_0007121 GO:0007120 biolink:BiologicalProcess axial cellular bud site selection The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell. go-plus.json axial budding|axial bud site selection http://purl.obolibrary.org/obo/GO_0007120 CHEBI:84793 biolink:ChemicalSubstance trans-dec-3-enoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84793 chebi_ph7_3 GO:0046739 biolink:BiologicalProcess transport of virus in multicellular host The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs). go-plus.json viral spread within multicellular host|spread of virus within multicellular host|spread of virus in multicellular host http://purl.obolibrary.org/obo/GO_0046739 GO:0046738 biolink:BiologicalProcess induction of innate immune response in host by virus The intentional, virally-encoded stimulation of an innate host defense response to viral infection. go-plus.json active viral induction of innate immune response in host|active induction of innate immune response in host by virus http://purl.obolibrary.org/obo/GO_0046738 CHEBI:84791 biolink:ChemicalSubstance (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84791 chebi_ph7_3 CHEBI:84790 biolink:ChemicalSubstance trans-3-hexenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84790 chebi_ph7_3 GO:0046737 biolink:BiologicalProcess induction of cell-mediated immune response in host by virus The intentional, virally-encoded stimulation of a cell-mediated host defense response to viral infection. go-plus.json active induction of cell-mediated immune response in host by virus|active viral induction of cell-mediated immune response in host http://purl.obolibrary.org/obo/GO_0046737 GO:0046736 biolink:BiologicalProcess induction of humoral immune response in host by virus The intentional, virally-encoded stimulation of a host humoral defense response to viral infection. go-plus.json active viral induction of humoral immune response in host|active induction of humoral immune response in host by virus http://purl.obolibrary.org/obo/GO_0046736 GO:0046735 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046735 GO:0046745 biolink:BiologicalProcess viral capsid secondary envelopment The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope. go-plus.json viral budding from plasma membrane by viral capsid re-envelopment|virus budding from ER membrane by viral capsid re-envelopment|plasma membrane viral budding during viral capsid re-envelopment|virus budding from nuclear membrane during viral capsid re-envelopment|virus budding from plasma membrane during viral capsid re-envelopment|virus budding from Golgi membrane during viral capsid re-envelopment|viral budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from outer nuclear membrane during viral capsid re-envelopment|inner nuclear membrane viral budding during viral capsid re-envelopment|virus budding from inner nuclear membrane during viral capsid re-envelopment|virus budding from Golgi membrane by viral capsid re-envelopment|virus budding from nuclear membrane by viral capsid re-envelopment|viral budding from ER membrane during viral capsid re-envelopment|virus budding from outer nuclear membrane by viral capsid re-envelopment|viral budding from nuclear membrane during viral capsid re-envelopment|viral budding from ER membrane by viral capsid re-envelopment|viral budding from Golgi membrane during viral capsid re-envelopment|viral budding from outer nuclear membrane during viral capsid re-envelopment|endoplasmic reticulum membrane viral budding during viral capsid re-envelopment|virus budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from ER membrane during viral capsid re-envelopment|ER membrane viral budding during viral capsid re-envelopment|viral budding from Golgi membrane by viral capsid re-envelopment|viral budding from nuclear membrane by viral capsid re-envelopment|viral budding from plasma membrane during viral capsid re-envelopment|viral capsid re-envelopment|outer nuclear membrane viral budding during viral capsid re-envelopment|nuclear membrane viral budding during viral capsid re-envelopment|viral budding from outer nuclear membrane by viral capsid re-envelopment|Golgi membrane viral budding during viral capsid re-envelopment|viral budding from inner nuclear membrane during viral capsid re-envelopment http://purl.obolibrary.org/obo/GO_0046745 GO:0046744 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046744 GO:0046743 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046743 GO:0046742 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046742 GO:0046741 biolink:BiologicalProcess transport of virus in host, tissue to tissue The transport of a virus between tissues in a multicellular organism. go-plus.json tissue to tissue spread of virus within host|viral spread within host, tissue to tissue|spread of virus within host, tissue to tissue|spread of virus in host, tissue to tissue http://purl.obolibrary.org/obo/GO_0046741 GO:0046740 biolink:BiologicalProcess transport of virus in host, cell to cell The transport of a virus between adjacent cells in a multicellular organism. VZ:1018 go-plus.json spread of virus in host, cell to cell|intercellular virus transport|cell to cell spread of virus within host|viral spread within host, cell to cell|spread of virus within host, cell to cell http://purl.obolibrary.org/obo/GO_0046740 GO:0071709 biolink:BiologicalProcess membrane assembly The aggregation, arrangement and bonding together of a set of components to form a membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0071709 GO:0071708 biolink:BiologicalProcess immunoglobulin light chain V-J recombination The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). go-plus.json immunoglobulin V-J joining|immunoglobulin V(D)J recombination|immunoglobulin V(D)J joining http://purl.obolibrary.org/obo/GO_0071708 GO:0071707 biolink:BiologicalProcess immunoglobulin heavy chain V-D-J recombination The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). go-plus.json immunoglobulin V(D)J recombination|immunoglobulin V-D-J joining|immunoglobulin V(D)J joining http://purl.obolibrary.org/obo/GO_0071707 GO:0071706 biolink:BiologicalProcess tumor necrosis factor superfamily cytokine production The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TNFSF cytokine production|TNF superfamily production http://purl.obolibrary.org/obo/GO_0071706 gocheck_do_not_annotate GO:0071705 biolink:BiologicalProcess nitrogen compound transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0071705 GO:0046749 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046749 GO:0071704 biolink:BiologicalProcess organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. go-plus.json organic molecular entity metabolism|organic substance metabolism|organic molecular entity metabolic process http://purl.obolibrary.org/obo/GO_0071704 GO:0046748 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046748 GO:0071703 biolink:BiologicalProcess detection of organic substance The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal. go-plus.json http://purl.obolibrary.org/obo/GO_0071703 GO:0046747 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046747 GO:0071702 biolink:BiologicalProcess organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. go-plus.json http://purl.obolibrary.org/obo/GO_0071702 GO:0046746 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046746 GO:0071701 biolink:BiologicalProcess regulation of MAPK export from nucleus Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm. go-plus.json regulation of MAPK export out of nucleus|regulation of cytoplasmic translocation of MAP kinase|regulation of cytoplasmic translocation of mitogen-activated protein kinase|regulation of MAPK export from cell nucleus|regulation of MAPK transport from nucleus to cytoplasm|regulation of MAPK-nucleus export http://purl.obolibrary.org/obo/GO_0071701 GO:0071700 biolink:BiologicalProcess olfactory placode maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0071700 GO:0007109 biolink:BiologicalProcess obsolete cytokinesis, completion of separation OBSOLETE. The process of finishing cell separation, which results in two physically separated cells. go-plus.json cytokinesis, completion of separation|completion of separation involved in cytokinesis http://purl.obolibrary.org/obo/GO_0007109 GO:0007108 biolink:BiologicalProcess obsolete cytokinesis, initiation of separation OBSOLETE. The process involved in starting cell separation. go-plus.json cytokinesis, initiation of separation|initiation of separation involved in cytokinesis http://purl.obolibrary.org/obo/GO_0007108 GO:0007107 biolink:BiologicalProcess membrane addition at site of cytokinesis Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion. go-plus.json cytokinesis, membrane recruitment/generation http://purl.obolibrary.org/obo/GO_0007107 GO:0007106 biolink:BiologicalProcess obsolete cytokinesis, protein recruitment OBSOLETE. (Was not defined before being made obsolete). go-plus.json cytokinesis, protein recruitment http://purl.obolibrary.org/obo/GO_0007106 GO:0007105 biolink:BiologicalProcess cytokinesis, site selection The process of marking the place where cytokinesis will occur. go-plus.json site selection involved in cytokinesis|site selection involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_0007105 GO:0007104 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007104 GO:0046756 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046756 GO:0046755 biolink:BiologicalProcess viral budding A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space. VZ:1947 go-plus.json virus budding|viral capsid envelopment|virion budding http://purl.obolibrary.org/obo/GO_0046755 GO:0007103 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007103 GO:0046754 biolink:BiologicalProcess viral exocytosis The exit of enveloped or unenveloped virion particles from the host cell by exocytosis, without causing cell lysis. go-plus.json http://purl.obolibrary.org/obo/GO_0046754 GO:0007102 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007102 GO:0046753 biolink:BiologicalProcess non-lytic viral release The exit of a viral particle from a cell that does not involve cell lysis. go-plus.json http://purl.obolibrary.org/obo/GO_0046753 GO:0007101 biolink:BiologicalProcess obsolete male meiosis centrosome cycle OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism. go-plus.json centrosome cycle involved in male meiotic cell cycle http://purl.obolibrary.org/obo/GO_0007101 GO:0046752 biolink:BiologicalProcess viral capsid precursor transport to host cell nucleus Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid. go-plus.json establishment and maintenance of viral capsid precursor localization in nucleus|localization of viral capsid precursors in nucleus|nuclear localization of viral capsid precursors|viral capsid precursor localization in host cell nucleus|viral capsid precursor localisation in host cell nucleus|viral capsid precursor localization to host cell nucleus http://purl.obolibrary.org/obo/GO_0046752 GO:0007100 biolink:BiologicalProcess mitotic centrosome separation Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle. go-plus.json http://purl.obolibrary.org/obo/GO_0007100 GO:0046751 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046751 GO:0046750 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046750 CHEBI:59793 biolink:ChemicalSubstance monothioacetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59793 chebi_ph7_3 CHEBI:59792 biolink:ChemicalSubstance thioacetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59792 CHEBI:59791 biolink:ChemicalSubstance gibberellin A3 O-beta-D-glucoside(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59791 chebi_ph7_3 GO:0046759 biolink:BiologicalProcess obsolete lytic virus budding from plasma membrane OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host nuclear membrane system, resulting in envelopment of the virus and cell lysis. go-plus.json lytic plasma membrane viral budding|lytic viral budding from plasma membrane|lytic virus budding from plasma membrane http://purl.obolibrary.org/obo/GO_0046759 GO:0046758 biolink:BiologicalProcess obsolete lytic virus budding from Golgi membrane OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host Golgi membrane system, resulting in envelopment of the virus and cell lysis. go-plus.json lytic Golgi membrane viral budding|lytic viral budding from Golgi membrane|lytic virus budding from Golgi membrane http://purl.obolibrary.org/obo/GO_0046758 GO:0046757 biolink:BiologicalProcess obsolete lytic virus budding from ER membrane OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host endoplasmic reticulum membrane system, resulting in envelopment of the virus and cell lysis. go-plus.json lytic virus budding from ER membrane|lytic ER membrane viral budding|lytic endoplasmic reticulum membrane viral budding|lytic viral budding from ER membrane http://purl.obolibrary.org/obo/GO_0046757 CHEBI:176429 biolink:ChemicalSubstance a (Kdo)2-lipid IVA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176429 CHEBI:176428 biolink:ChemicalSubstance a Kdo-lipid IVA(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176428 UBERON:0002316 biolink:AnatomicalEntity white matter Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system. go-plus.json white matter of neuraxis|white mater|CNS tracts and commissures|CNS white matter|substantia alba|CNS tract/commissure|neuronal white matter|white substance http://purl.obolibrary.org/obo/UBERON_0002316 UBERON:0002319 biolink:AnatomicalEntity mesangium The inner layer of the glomerulus, within the basement membrane surrounding the glomerular capillaries. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002319 UBERON:0002318 biolink:AnatomicalEntity white matter of spinal cord The regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. go-plus.json substantia alba medullae spinalis|white matter of neuraxis of spinal cord|white substance of spinal cord|spinal cord white substance|spinal cord white matter|spinal cord white matter of neuraxis http://purl.obolibrary.org/obo/UBERON_0002318 CL:2000078 biolink:Cell placental pericyte Any pericyte cell that is part of a placenta. go-plus.json http://purl.obolibrary.org/obo/CL_2000078 GO:0046767 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046767 GO:0046766 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046766 GO:0046765 biolink:BiologicalProcess viral budding from nuclear membrane A viral budding that starts with formation of a membrane curvature in the host nuclear membrane. go-plus.json virus budding from nuclear membrane during viral capsid envelopment|virus budding from nuclear membrane|nuclear membrane viral budding|nuclear membrane viral budding during viral capsid envelopment|viral budding from nuclear membrane by viral capsid envelopment|virus budding from nuclear membrane by viral capsid envelopment|viral budding from nuclear membrane during viral capsid envelopment http://purl.obolibrary.org/obo/GO_0046765 GO:0046764 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046764 CL:2000074 biolink:Cell splenocyte Any leukocyte that is part of a spleen. go-plus.json http://purl.obolibrary.org/obo/CL_2000074 GO:0046763 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046763 GO:0046762 biolink:BiologicalProcess viral budding from endoplasmic reticulum membrane A viral budding that starts with formation of a membrane curvature in the host ER membrane. go-plus.json viral budding from ER membrane|viral budding from ER membrane during viral capsid envelopment|virus budding from ER membrane by viral capsid envelopment|virus budding from ER membrane during viral capsid envelopment|virus budding from ER membrane|viral budding from ER membrane by viral capsid envelopment|ER membrane viral budding|ER membrane viral budding during viral capsid envelopment|endoplasmic reticulum membrane viral budding|endoplasmic reticulum membrane viral budding during viral capsid envelopment http://purl.obolibrary.org/obo/GO_0046762 GO:0046761 biolink:BiologicalProcess viral budding from plasma membrane A viral budding that starts with formation of a membrane curvature in the host plasma membrane. go-plus.json virus budding from plasma membrane during viral capsid envelopment|virus budding from plasma membrane|viral budding from plasma membrane by viral capsid envelopment|plasma membrane viral budding|plasma membrane viral budding during viral capsid envelopment|viral budding from plasma membrane during viral capsid envelopment|virus budding from plasma membrane by viral capsid envelopment http://purl.obolibrary.org/obo/GO_0046761 GO:0046760 biolink:BiologicalProcess viral budding from Golgi membrane A viral budding that starts with formation of a membrane curvature in the host Golgi membrane. go-plus.json virus budding from Golgi membrane during viral capsid envelopment|virus budding from Golgi membrane|Golgi membrane viral budding|viral budding from Golgi membrane by viral capsid envelopment|Golgi membrane viral budding during viral capsid envelopment|viral budding from Golgi membrane during viral capsid envelopment|virus budding from Golgi membrane by viral capsid envelopment http://purl.obolibrary.org/obo/GO_0046760 CL:2000075 biolink:Cell anterior visceral endoderm cell Any endodermal cell that is part of a anterior visceral endoderm. go-plus.json http://purl.obolibrary.org/obo/CL_2000075 CHEBI:59783 biolink:ChemicalSubstance 2-hydroxy-4-methylvaleric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59783 GO:0071729 biolink:BiologicalProcess beak morphogenesis The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. go-plus.json http://purl.obolibrary.org/obo/GO_0071729 GO:0071728 biolink:BiologicalProcess beak development The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. go-plus.json http://purl.obolibrary.org/obo/GO_0071728 GO:0071727 biolink:BiologicalProcess cellular response to triacyl bacterial lipopeptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus. go-plus.json cellular response to triacylated bacterial lipoprotein http://purl.obolibrary.org/obo/GO_0071727 CHEBI:59780 biolink:ChemicalSubstance cyclic hemiketal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59780 GO:0071726 biolink:BiologicalProcess cellular response to diacyl bacterial lipopeptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus. go-plus.json cellular response to diacylated bacterial lipoprotein http://purl.obolibrary.org/obo/GO_0071726 GO:0071725 biolink:BiologicalProcess response to triacyl bacterial lipopeptide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus. go-plus.json response to triacylated bacterial lipoprotein http://purl.obolibrary.org/obo/GO_0071725 GO:0046769 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046769 GO:0071724 biolink:BiologicalProcess response to diacyl bacterial lipopeptide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus. go-plus.json response to diacylated bacterial lipoprotein http://purl.obolibrary.org/obo/GO_0071724 GO:0046768 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046768 UBERON:0002324 biolink:AnatomicalEntity muscle of back Any muscle organ that is part of a back [Automatically generated definition]. go-plus.json back muscle organ|muscle organ of back|back muscle http://purl.obolibrary.org/obo/UBERON_0002324 GO:0071723 biolink:MolecularActivity lipopeptide binding Binding to a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids. go-plus.json bacterial lipoprotein binding|bacterial lipopeptide binding http://purl.obolibrary.org/obo/GO_0071723 UBERON:0002323 biolink:AnatomicalEntity coelemic cavity lumen The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities. go-plus.json space of body compartment|celom|ventral body cavity|coelomic cavity lumen|coelome|main body cavity|hemocoel|coelom|coelomic cavity|body cavity http://purl.obolibrary.org/obo/UBERON_0002323 GO:0071722 biolink:BiologicalProcess detoxification of arsenic-containing substance Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds. go-plus.json detoxification of arsenic http://purl.obolibrary.org/obo/GO_0071722 UBERON:0002326 biolink:AnatomicalEntity lamina propria of urethra A lamina propria that is part of a urethra [Automatically generated definition]. go-plus.json urethral lamina propria|urethra lamina propria mucosae|urethra lamina propria mucosa|urethra lamina propria|lamina propria mucosae of urethra|lamina propria mucosa of urethra http://purl.obolibrary.org/obo/UBERON_0002326 GO:0071721 biolink:BiologicalProcess sodium-independent thromboxane transport The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0071721 UBERON:0002325 biolink:AnatomicalEntity epithelium of urethra The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.. go-plus.json urethral epithelium|urethra epithelium|epithelial tissue of urethra|urethral seam|urethra epithelial tissue|urethral plate http://purl.obolibrary.org/obo/UBERON_0002325 CHEBI:59789 biolink:ChemicalSubstance S-adenosyl-L-methionine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59789 chebi_ph7_3 GO:0071720 biolink:BiologicalProcess sodium-independent prostaglandin transport The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0071720 UBERON:0002320 biolink:AnatomicalEntity glomerular mesangium A thin membrane which helps to support the capillary loops in a renal glomerulus. It is connective tissue composed of mesangial cells - myofibroblasts phenotypically related to vascular smooth muscle cells (muscle, smooth, vascular), phagocytes and the mesangial extracellular matrix. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002320 CHEBI:176425 biolink:ChemicalSubstance a lipid IVA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176425 CHEBI:59786 biolink:ChemicalSubstance thioaldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_59786 GO:0046770 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046770 GO:1900606 biolink:BiologicalProcess tensidol B metabolic process The chemical reactions and pathways involving tensidol B. go-plus.json tensidol B metabolism http://purl.obolibrary.org/obo/GO_1900606 GO:1900605 biolink:BiologicalProcess tensidol A biosynthetic process The chemical reactions and pathways resulting in the formation of tensidol A. go-plus.json tensidol A synthesis|tensidol A formation|tensidol A biosynthesis|tensidol A anabolism http://purl.obolibrary.org/obo/GO_1900605 GO:1900608 biolink:BiologicalProcess tensidol B biosynthetic process The chemical reactions and pathways resulting in the formation of tensidol B. go-plus.json tensidol B synthesis|tensidol B formation|tensidol B biosynthesis|tensidol B anabolism http://purl.obolibrary.org/obo/GO_1900608 CL:2000061 biolink:Cell placental amniotic mesenchymal stromal cell Any mesenchymal stem cell that is part of a placenta. go-plus.json http://purl.obolibrary.org/obo/CL_2000061 GO:1900607 biolink:BiologicalProcess tensidol B catabolic process The chemical reactions and pathways resulting in the breakdown of tensidol B. go-plus.json tensidol B catabolism|tensidol B degradation|tensidol B breakdown http://purl.obolibrary.org/obo/GO_1900607 CHEBI:21188 biolink:ChemicalSubstance L-2'-bromophenylalanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_21188 CL:2000060 biolink:Cell placental villous trophoblast A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua. go-plus.json vCTB|villous cytotrophoblast http://purl.obolibrary.org/obo/CL_2000060 GO:1900602 biolink:BiologicalProcess endocrocin biosynthetic process The chemical reactions and pathways resulting in the formation of endocrocin. go-plus.json endocrocin anabolism|endocrocin biosynthesis|endocrocin synthesis|endocrocin formation http://purl.obolibrary.org/obo/GO_1900602 GO:1900601 biolink:BiologicalProcess endocrocin catabolic process The chemical reactions and pathways resulting in the breakdown of endocrocin. go-plus.json endocrocin degradation|endocrocin breakdown|endocrocin catabolism http://purl.obolibrary.org/obo/GO_1900601 UBERON:0002305 biolink:AnatomicalEntity layer of hippocampus The layers of the laminar structure of the hippocampus. go-plus.json hippocampus layer|layer of cornu ammonis|cytoarchitectural fields of hippocampal formation|hippocampus proper layer http://purl.obolibrary.org/obo/UBERON_0002305 GO:1900604 biolink:BiologicalProcess tensidol A catabolic process The chemical reactions and pathways resulting in the breakdown of tensidol A. go-plus.json tensidol A catabolism|tensidol A degradation|tensidol A breakdown http://purl.obolibrary.org/obo/GO_1900604 UBERON:0002308 biolink:AnatomicalEntity nucleus of brain A neural nucleus that is part of the brain. go-plus.json brain nucleus|brain nuclei http://purl.obolibrary.org/obo/UBERON_0002308 UBERON:0002307 biolink:AnatomicalEntity choroid plexus of lateral ventricle Part of choroid plexus contained in the lateral ventricle go-plus.json lateral ventricle choroid plexus|lateral ventricle chorioid plexus of cerebral hemisphere|choroid plexus telencephalic ventricle|chorioid plexus of lateral ventricle|chorioid plexus of cerebral hemisphere of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002307 GO:1900603 biolink:BiologicalProcess tensidol A metabolic process The chemical reactions and pathways involving tensidol A. go-plus.json tensidol A metabolism http://purl.obolibrary.org/obo/GO_1900603 GO:0046778 biolink:BiologicalProcess modification by virus of host mRNA processing Any viral process that interferes with the processing of mRNA in the host cell. go-plus.json viral perturbation of host mRNA processing http://purl.obolibrary.org/obo/GO_0046778 CL:2000067 biolink:Cell cardiac atrium fibroblast Any fibroblast that is part of a cardiac atrium. go-plus.json http://purl.obolibrary.org/obo/CL_2000067 CL:2000066 biolink:Cell cardiac ventricle fibroblast Any fibroblast that is part of a cardiac ventricle. go-plus.json http://purl.obolibrary.org/obo/CL_2000066 GO:0046777 biolink:BiologicalProcess protein autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). Wikipedia:Autophosphorylation go-plus.json protein amino acid autophosphorylation http://purl.obolibrary.org/obo/GO_0046777 GO:1900600 biolink:BiologicalProcess endocrocin metabolic process The chemical reactions and pathways involving endocrocin. go-plus.json endocrocin metabolism http://purl.obolibrary.org/obo/GO_1900600 CL:2000069 biolink:Cell gallbladder fibroblast Any fibroblast that is part of a gallbladder. go-plus.json http://purl.obolibrary.org/obo/CL_2000069 GO:0046776 biolink:BiologicalProcess suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. VZ:819 go-plus.json inhibition of host MHC class I molecule presentation by virus|suppression by virus of host MHC class I cell surface presentation|major histocompatibility complex|suppression by virus of MHC class I cell surface presentation in host|negative regulation by virus of MHC class I cell surface presentation http://purl.obolibrary.org/obo/GO_0046776 GO:0046775 biolink:BiologicalProcess suppression by virus of host cytokine production Any viral process that results in the inhibition of host cell cytokine production. go-plus.json negative regulation by virus of host cytokine production http://purl.obolibrary.org/obo/GO_0046775 CL:2000068 biolink:Cell pericardium fibroblast Any fibroblast that is part of a pericardium. go-plus.json http://purl.obolibrary.org/obo/CL_2000068 GO:0046774 biolink:BiologicalProcess suppression by virus of host intracellular interferon activity Any viral process that results in the inhibition of interferon activity within the host cell. go-plus.json suppression by virus of intracellular interferon activity in host|negative regulation by virus of intracellular interferon activity http://purl.obolibrary.org/obo/GO_0046774 CL:2000063 biolink:Cell ovarian fibroblast Any fibroblast that is part of a female gonad. go-plus.json http://purl.obolibrary.org/obo/CL_2000063 GO:0046773 biolink:BiologicalProcess suppression by virus of host translation termination Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA. go-plus.json suppression by virus of host termination of protein biosynthetic process|viral inhibition of termination of host cell protein biosynthetic process|viral inhibition of termination of host cell protein biosynthesis|negative regulation by virus of host cell protein biosynthesis shutoff|negative regulation by virus of host cell protein biosynthetic process shutoff|viral inhibition of host cell protein biosynthetic process shutoff|viral inhibition of host cell protein biosynthesis shutoff|viral suppression of termination by host of host cell protein biosynthesis|viral suppression of termination by host of host cell protein biosynthetic process http://purl.obolibrary.org/obo/GO_0046773 GO:0046772 biolink:BiologicalProcess viral budding from outer nuclear membrane The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope. go-plus.json virus budding from outer nuclear membrane by viral capsid envelopment|viral budding from outer nuclear membrane during viral capsid envelopment|virus budding from outer nuclear membrane during viral capsid envelopment|outer nuclear membrane viral budding during viral capsid envelopment http://purl.obolibrary.org/obo/GO_0046772 GO:0046771 biolink:BiologicalProcess viral budding from inner nuclear membrane The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope. go-plus.json viral budding from inner nuclear membrane during viral capsid envelopment|virus budding from inner nuclear membrane during viral capsid envelopment|viral budding from inner nuclear membrane by viral capsid envelopment|inner nuclear membrane viral budding during viral capsid envelopment|virus budding from inner nuclear membrane by viral capsid envelopment http://purl.obolibrary.org/obo/GO_0046771 CHEBI:45133 biolink:ChemicalSubstance pivalic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45133 CL:2000064 biolink:Cell ovarian surface epithelial cell Any epithelial cell that is part of a female gonad. go-plus.json http://purl.obolibrary.org/obo/CL_2000064 CHEBI:59772 biolink:ChemicalSubstance hemiketal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59772 chebi_ph7_3 GO:0071719 biolink:BiologicalProcess sodium-independent leukotriene transport The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. go-plus.json http://purl.obolibrary.org/obo/GO_0071719 GO:0071718 biolink:BiologicalProcess sodium-independent icosanoid transport The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds. go-plus.json sodium-independent eicosanoid transport http://purl.obolibrary.org/obo/GO_0071718 GO:0071717 biolink:BiologicalProcess thromboxane transport The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels. go-plus.json http://purl.obolibrary.org/obo/GO_0071717 CHEBI:59770 biolink:ChemicalSubstance cyclic acetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59770 GO:0071716 biolink:BiologicalProcess leukotriene transport The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. go-plus.json http://purl.obolibrary.org/obo/GO_0071716 GO:0071715 biolink:BiologicalProcess icosanoid transport The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds. go-plus.json eicosanoid transport http://purl.obolibrary.org/obo/GO_0071715 GO:0071714 biolink:MolecularActivity icosanoid transmembrane transporter activity Enables the transfer of icosanoids from one side of a membrane to the other. go-plus.json eicosanoid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0071714 GO:0046779 biolink:BiologicalProcess obsolete suppression by virus of expression of host genes with introns OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed. go-plus.json negative regulation by virus of expression of host genes with introns|viral inhibition of expression of host genes with introns http://purl.obolibrary.org/obo/GO_0046779 GO:0071713 biolink:MolecularActivity para-aminobenzoyl-glutamate hydrolase activity Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate. go-plus.json http://purl.obolibrary.org/obo/GO_0071713 GO:0071712 biolink:BiologicalProcess ER-associated misfolded protein catabolic process The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. go-plus.json endoplasmic reticulum-associated misfolded protein catabolism|proteasomal protein catabolism of misfolded ER proteins|ER-associated misfolded protein catabolism|ER-associated misfolded protein degradation|ER-associated misfolded protein breakdown|endoplasmic reticulum-associated misfolded protein catabolic process http://purl.obolibrary.org/obo/GO_0071712 GO:0071711 biolink:BiologicalProcess basement membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. go-plus.json basement membrane organisation http://purl.obolibrary.org/obo/GO_0071711 CHEBI:176431 biolink:ChemicalSubstance an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176431 GO:0071710 biolink:BiologicalProcess membrane macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell. go-plus.json membrane macromolecule formation|membrane macromolecule biosynthesis|membrane macromolecule anabolism|membrane macromolecule synthesis http://purl.obolibrary.org/obo/GO_0071710 UBERON:0002315 biolink:AnatomicalEntity gray matter of spinal cord The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue. go-plus.json gray substance of spinal cord|spinal cord grey matter|spinal cord gray matter|gray matter of spinal cord|grey matter of spinal cord|spinal cord grey substance|substantia grisea medullae spinalis|grey substance of spinal cord http://purl.obolibrary.org/obo/UBERON_0002315 CHEBI:176430 biolink:ChemicalSubstance a (Kdo)2-(acyl)-lipid IVA(6-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_176430 CHEBI:59779 biolink:ChemicalSubstance cyclic ketal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59779 UBERON:0002314 biolink:AnatomicalEntity midbrain tectum Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei (MM). go-plus.json mesencephalic tectum|tectum mesencephalicum|tectum of midbrain|tectum mesencephali|neuraxis tectum|t. mesencephali|tectum http://purl.obolibrary.org/obo/UBERON_0002314 CHEBI:59777 biolink:ChemicalSubstance ketal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59777 GO:1900609 biolink:BiologicalProcess F-9775A metabolic process The chemical reactions and pathways involving F-9775A. go-plus.json F-9775A metabolism http://purl.obolibrary.org/obo/GO_1900609 CHEBI:59776 biolink:ChemicalSubstance D-glyceraldehyde 3-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59776 chebi_ph7_3 GO:1900617 biolink:BiologicalProcess emericellamide A biosynthetic process The chemical reactions and pathways resulting in the formation of emericellamide A. go-plus.json emericellamide A biosynthesis|emericellamide A anabolism|emericellamide A synthesis|emericellamide A formation http://purl.obolibrary.org/obo/GO_1900617 GO:0046781 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046781 CL:2000092 biolink:Cell hair follicular keratinocyte Any keratinocyte that is part of a hair follicle. go-plus.json http://purl.obolibrary.org/obo/CL_2000092 GO:0046780 biolink:BiologicalProcess suppression by virus of host mRNA splicing Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production. go-plus.json viral dispersion of host splicing factors|negative regulation by virus of host mRNA splicing|viral inhibition of host mRNA splicing|suppression by virus of host splicing factor activity http://purl.obolibrary.org/obo/GO_0046780 GO:1900616 biolink:BiologicalProcess emericellamide A catabolic process The chemical reactions and pathways resulting in the breakdown of emericellamide A. go-plus.json emericellamide A degradation|emericellamide A breakdown|emericellamide A catabolism http://purl.obolibrary.org/obo/GO_1900616 GO:1900619 biolink:BiologicalProcess acetate ester metabolic process The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid. go-plus.json acetate ester metabolism|acetyl ester metabolism|acetyl ester metabolic process http://purl.obolibrary.org/obo/GO_1900619 GO:1900618 biolink:BiologicalProcess regulation of shoot system morphogenesis Any process that modulates the frequency, rate or extent of shoot morphogenesis. go-plus.json regulation of shoot morphogenesis http://purl.obolibrary.org/obo/GO_1900618 CL:2000093 biolink:Cell bronchus fibroblast of lung Any fibroblast of lung that is part of a bronchus. go-plus.json http://purl.obolibrary.org/obo/CL_2000093 GO:1900613 biolink:BiologicalProcess F-9775B catabolic process The chemical reactions and pathways resulting in the breakdown of F-9775B. go-plus.json F-9775B catabolism|F-9775B degradation|F-9775B breakdown http://purl.obolibrary.org/obo/GO_1900613 GO:1900612 biolink:BiologicalProcess F-9775B metabolic process The chemical reactions and pathways involving F-9775B. go-plus.json F-9775B metabolism http://purl.obolibrary.org/obo/GO_1900612 GO:1900615 biolink:BiologicalProcess emericellamide A metabolic process The chemical reactions and pathways involving emericellamide A. go-plus.json emericellamide A metabolism http://purl.obolibrary.org/obo/GO_1900615 CL:2000090 biolink:Cell dentate gyrus of hippocampal formation stellate cell Any stellate cell that is part of a dentate gyrus of hippocampal formation. go-plus.json http://purl.obolibrary.org/obo/CL_2000090 GO:1900614 biolink:BiologicalProcess F-9775B biosynthetic process The chemical reactions and pathways resulting in the formation of F-9775B. go-plus.json F-9775B synthesis|F-9775B formation|F-9775B biosynthesis|F-9775B anabolism http://purl.obolibrary.org/obo/GO_1900614 CHEBI:45129 biolink:ChemicalSubstance methylphosphonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45129 GO:0046789 biolink:MolecularActivity host cell surface receptor binding Binding to a receptor on the host cell surface. go-plus.json cell surface antigen activity, host-interacting|cell surface receptor ligand http://purl.obolibrary.org/obo/GO_0046789 goslim_chembl GO:0046788 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046788 GO:1900611 biolink:BiologicalProcess F-9775A biosynthetic process The chemical reactions and pathways resulting in the formation of F-9775A. go-plus.json F-9775A synthesis|F-9775A formation|F-9775A biosynthesis|F-9775A anabolism http://purl.obolibrary.org/obo/GO_1900611 GO:0046787 biolink:BiologicalProcess viral DNA repair The process of restoring viral DNA after damage or errors in replication. go-plus.json http://purl.obolibrary.org/obo/GO_0046787 GO:1900610 biolink:BiologicalProcess F-9775A catabolic process The chemical reactions and pathways resulting in the breakdown of F-9775A. go-plus.json F-9775A catabolism|F-9775A degradation|F-9775A breakdown http://purl.obolibrary.org/obo/GO_1900610 GO:0046786 biolink:BiologicalProcess viral replication complex formation and maintenance The process of organizing and assembling viral replication proteins in preparation for viral replication. go-plus.json http://purl.obolibrary.org/obo/GO_0046786 CHEBI:45126 biolink:ChemicalSubstance 7-aminomethyl-7-deazaguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_45126 GO:0046785 biolink:BiologicalProcess microtubule polymerization The addition of tubulin heterodimers to one or both ends of a microtubule. go-plus.json microtubule assembly|microtubule formation http://purl.obolibrary.org/obo/GO_0046785 GO:0046784 biolink:BiologicalProcess viral mRNA export from host cell nucleus The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation. go-plus.json intronless viral mRNA export from host nucleus|intronless viral mRNA transport from nucleus to cytoplasm|intronless viral mRNA-nucleus export|intronless viral mRNA export out of nucleus|intronless viral mRNA export from host cell nucleus http://purl.obolibrary.org/obo/GO_0046784 GO:0046783 biolink:BiologicalProcess modification by virus of host polysomes Any viral process that interferes with and inhibits the assembly and function of polysomes. go-plus.json viral perturbation of polysomes http://purl.obolibrary.org/obo/GO_0046783 GO:0046782 biolink:BiologicalProcess regulation of viral transcription Any process that modulates the frequency, rate or extent of the transcription of the viral genome. go-plus.json http://purl.obolibrary.org/obo/GO_0046782 CL:2000097 biolink:Cell midbrain dopaminergic neuron Any dopaminergic neuron that is part of a midbrain. go-plus.json http://purl.obolibrary.org/obo/CL_2000097 CHEBI:35795 biolink:ChemicalSubstance polyprenylbenzoquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_35795 NCBITaxon:142796 biolink:OrganismalEntity Eumycetozoa go-plus.json Mycetozoa|Eumycetozoa Zopf, 1884|mycetozoans http://purl.obolibrary.org/obo/NCBITaxon_142796 CHEBI:35794 biolink:ChemicalSubstance tetrapyrrole fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35794 GO:0071749 biolink:CellularComponent polymeric IgA immunoglobulin complex A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json pIgA antibody|pIgA1 antibody|polymeric IgA1 antibody|polymeric IgA antibody http://purl.obolibrary.org/obo/GO_0071749 GO:0071748 biolink:CellularComponent monomeric IgA immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json monomeric IgA antibody|monomeric IgA1 antibody|monomeric IgA2 antibody http://purl.obolibrary.org/obo/GO_0071748 GO:0071747 biolink:CellularComponent IgA B cell receptor complex An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json membrane-bound IgA2|membrane-bound IgA1|membrane-bound IgA|surface IgA2|surface IgA1|surface IgA http://purl.obolibrary.org/obo/GO_0071747 GO:0071746 biolink:CellularComponent IgA immunoglobulin complex, circulating A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json IgA antibody|IgA1 antibody|IgA2 antibody http://purl.obolibrary.org/obo/GO_0071746 UBERON:0002302 biolink:AnatomicalEntity myocardium of atrium the atrial part of middle layer of the heart, comprised of involuntary muscle go-plus.json atrial myocardium|atrium cardiac muscle|atrium myocardium http://purl.obolibrary.org/obo/UBERON_0002302 GO:0071745 biolink:CellularComponent IgA immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json IgA1 antibody|IgA2 antibody http://purl.obolibrary.org/obo/GO_0071745 UBERON:0002301 biolink:AnatomicalEntity layer of neocortex One of the layers of the neocortex. go-plus.json lamina of neocortex|layer of neocortex|cerebral cortex layer|cortical layer|neocortex layer http://purl.obolibrary.org/obo/UBERON_0002301 GO:0071744 biolink:CellularComponent IgE B cell receptor complex An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json membrane-bound IgE|surface IgE http://purl.obolibrary.org/obo/GO_0071744 CHEBI:59769 biolink:ChemicalSubstance acetal go-plus.json http://purl.obolibrary.org/obo/CHEBI_59769 CHEBI:59768 biolink:ChemicalSubstance aliphatic aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_59768 UBERON:0002304 biolink:AnatomicalEntity layer of dentate gyrus One of the three layers of the dentate gyrus of the hippocampal formation. go-plus.json dentate gyrus layer|dentate gyrus cell layer http://purl.obolibrary.org/obo/UBERON_0002304 GO:0071743 biolink:CellularComponent IgE immunoglobulin complex, circulating A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json IgE antibody http://purl.obolibrary.org/obo/GO_0071743 UBERON:0002303 biolink:AnatomicalEntity juxtaglomerular apparatus An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. go-plus.json juxtaglomerular complex|complexus juxtaglomerularis http://purl.obolibrary.org/obo/UBERON_0002303 GO:0071742 biolink:CellularComponent IgE immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0071742 GO:0071741 biolink:CellularComponent IgD immunoglobulin complex, GPI-anchored A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells. go-plus.json GPI-anchored IgD http://purl.obolibrary.org/obo/GO_0071741 GO:0071740 biolink:CellularComponent IgD B cell receptor complex An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json membrane-bound IgD|surface IgD http://purl.obolibrary.org/obo/GO_0071740 CHEBI:35790 biolink:ChemicalSubstance oxazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35790 CHEBI:59765 biolink:ChemicalSubstance boric acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_59765 GO:1900628 biolink:BiologicalProcess positive regulation of arugosin biosynthetic process Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process. go-plus.json activation of arugosin anabolism|up-regulation of arugosin formation|activation of arugosin biosynthesis|activation of arugosin synthesis|positive regulation of arugosin anabolism|up regulation of arugosin anabolism|activation of arugosin formation|up-regulation of arugosin biosynthetic process|up-regulation of arugosin biosynthesis|positive regulation of arugosin synthesis|up regulation of arugosin synthesis|positive regulation of arugosin formation|up regulation of arugosin formation|upregulation of arugosin biosynthetic process|upregulation of arugosin anabolism|upregulation of arugosin biosynthesis|upregulation of arugosin synthesis|upregulation of arugosin formation|up-regulation of arugosin anabolism|up regulation of arugosin biosynthetic process|up regulation of arugosin biosynthesis|positive regulation of arugosin biosynthesis|activation of arugosin biosynthetic process|up-regulation of arugosin synthesis http://purl.obolibrary.org/obo/GO_1900628 GO:0046792 biolink:BiologicalProcess suppression by virus of host cell cycle arrest Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur. go-plus.json viral inhibition of cell cycle arrest|negative regulation by virus of cell cycle arrest http://purl.obolibrary.org/obo/GO_0046792 CHEBI:21165 biolink:ChemicalSubstance GDP-alpha-D-mannosylchitobiosyldiphosphodolichol go-plus.json http://purl.obolibrary.org/obo/CHEBI_21165 GO:1900627 biolink:BiologicalProcess negative regulation of arugosin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process. go-plus.json down-regulation of arugosin biosynthetic process|negative regulation of arugosin biosynthesis|down-regulation of arugosin anabolism|negative regulation of arugosin anabolism|down-regulation of arugosin biosynthesis|down-regulation of arugosin synthesis|negative regulation of arugosin synthesis|inhibition of arugosin biosynthetic process|down-regulation of arugosin formation|negative regulation of arugosin formation|downregulation of arugosin anabolism|inhibition of arugosin biosynthesis|down regulation of arugosin anabolism|downregulation of arugosin synthesis|downregulation of arugosin formation|down regulation of arugosin synthesis|down regulation of arugosin biosynthetic process|down regulation of arugosin biosynthesis|inhibition of arugosin anabolism|down regulation of arugosin formation|downregulation of arugosin biosynthetic process|downregulation of arugosin biosynthesis|inhibition of arugosin synthesis|inhibition of arugosin formation http://purl.obolibrary.org/obo/GO_1900627 GO:0046791 biolink:BiologicalProcess obsolete suppression by virus of host complement neutralization OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell. go-plus.json suppression by virus of host complement neutralization|negative regulation by virus of host complement neutralization http://purl.obolibrary.org/obo/GO_0046791 CHEBI:21167 biolink:ChemicalSubstance GDP-hexose go-plus.json http://purl.obolibrary.org/obo/CHEBI_21167 GO:0046790 biolink:MolecularActivity virion binding Binding to a virion, either by binding to components of the capsid or the viral envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0046790 GO:1900629 biolink:BiologicalProcess methanophenazine metabolic process The chemical reactions and pathways involving methanophenazine. go-plus.json methanophenazine metabolism http://purl.obolibrary.org/obo/GO_1900629 GO:1900624 biolink:BiologicalProcess negative regulation of monocyte aggregation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation. go-plus.json downregulation of monocyte aggregation|negative regulation of mononuclear phagocyte aggregation|down-regulation of mononuclear phagocyte aggregation|down regulation of monocyte aggregation|inhibition of monocyte aggregation|inhibition of mononuclear phagocyte aggregation|down regulation of mononuclear phagocyte aggregation|down-regulation of monocyte aggregation|downregulation of mononuclear phagocyte aggregation http://purl.obolibrary.org/obo/GO_1900624 CHEBI:21169 biolink:ChemicalSubstance GDP-sugar go-plus.json http://purl.obolibrary.org/obo/CHEBI_21169 GO:1900623 biolink:BiologicalProcess regulation of monocyte aggregation Any process that modulates the frequency, rate or extent of monocyte aggregation. go-plus.json regulation of mononuclear phagocyte aggregation http://purl.obolibrary.org/obo/GO_1900623 CHEBI:21168 biolink:ChemicalSubstance GDP-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_21168 GO:1900626 biolink:BiologicalProcess regulation of arugosin biosynthetic process Any process that modulates the frequency, rate or extent of arugosin biosynthetic process. go-plus.json regulation of arugosin anabolism|regulation of arugosin synthesis|regulation of arugosin formation|regulation of arugosin biosynthesis http://purl.obolibrary.org/obo/GO_1900626 GO:1900625 biolink:BiologicalProcess positive regulation of monocyte aggregation Any process that activates or increases the frequency, rate or extent of monocyte aggregation. go-plus.json activation of mononuclear phagocyte aggregation|upregulation of monocyte aggregation|up-regulation of mononuclear phagocyte aggregation|up-regulation of monocyte aggregation|activation of monocyte aggregation|upregulation of mononuclear phagocyte aggregation|up regulation of mononuclear phagocyte aggregation|up regulation of monocyte aggregation|positive regulation of mononuclear phagocyte aggregation http://purl.obolibrary.org/obo/GO_1900625 GO:1900620 biolink:BiologicalProcess acetate ester biosynthetic process The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid. go-plus.json acetate ester biosynthesis|acetyl ester biosynthesis|acetyl ester biosynthetic process|acetate ester anabolism|acetate ester synthesis|acetate ester formation http://purl.obolibrary.org/obo/GO_1900620 CL:2000089 biolink:Cell dentate gyrus of hippocampal formation granule cell The principal cell type of the dentate gyrus. go-plus.json http://purl.obolibrary.org/obo/CL_2000089 GO:0046799 biolink:BiologicalProcess recruitment of helicase-primase complex to DNA lesions The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair. go-plus.json http://purl.obolibrary.org/obo/GO_0046799 GO:1900622 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter. go-plus.json upregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcription activation|calcineurin-mediated activation of transcription|upregulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcriptional induction|up-regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of global transcription from Pol II promoter by calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling|positive regulation of transcription from Pol II promoter by calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1900622 GO:0046798 biolink:CellularComponent viral portal complex A multimeric ring of proteins through which the DNA enters and exits the viral capsid. go-plus.json http://purl.obolibrary.org/obo/GO_0046798 GO:1900621 biolink:BiologicalProcess obsolete regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling OBSOLETE. Calcium-mediated signaling that results in regulation of transcription from an RNA polymerase II promoter. go-plus.json regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling|regulation of transcription from Pol II promoter by calcium-mediated signaling|regulation of global transcription from Pol II promoter by calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling http://purl.obolibrary.org/obo/GO_1900621 GO:0046797 biolink:BiologicalProcess viral procapsid maturation The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure. UniProtKB-KW:KW-1273 go-plus.json capsid maturation|virion maturation|viral capsid maturation http://purl.obolibrary.org/obo/GO_0046797 CL:2000085 biolink:Cell mononuclear cell of umbilical cord Any mononuclear cell that is part of a umbilical cord. go-plus.json http://purl.obolibrary.org/obo/CL_2000085 GO:0046796 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046796 CHEBI:21161 biolink:ChemicalSubstance GDP-D-mannuronic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21161 GO:0046795 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046795 GO:0046794 biolink:BiologicalProcess transport of virus The directed movement of a virus, or part of a virus, into, out of, or within a host cell. go-plus.json virion transport|viral transport http://purl.obolibrary.org/obo/GO_0046794 goslim_pir GO:0046793 biolink:BiologicalProcess induction by virus of phosphorylation of host RNA polymerase II Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II. go-plus.json induction by virus of modification of host RNA polymerase II|virus-induced modification of host RNA polymerase II http://purl.obolibrary.org/obo/GO_0046793 UBERON:0016928 biolink:AnatomicalEntity metaphysis of fibula A metaphysis that is part of a fibula. go-plus.json fibular metaphysis|fibula metaphysis http://purl.obolibrary.org/obo/UBERON_0016928 GO:0071739 biolink:CellularComponent IgD immunoglobulin complex, circulating A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json IgD antibody http://purl.obolibrary.org/obo/GO_0071739 GO:0071738 biolink:CellularComponent IgD immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0071738 GO:0071737 biolink:CellularComponent IgG B cell receptor complex An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json membrane-bound IgG2c|surface IgG4|membrane-bound IgG2b|surface IgG3|membrane-bound IgG2a|surface IgG2|surface IgG1|surface IgG|membrane-bound IgG|surface IgG2c|membrane-bound IgG4|surface IgG2b|membrane-bound IgG3|surface IgG2a|membrane-bound IgG2|membrane-bound IgG1 http://purl.obolibrary.org/obo/GO_0071737 GO:0071736 biolink:CellularComponent IgG immunoglobulin complex, circulating A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json IgG1 antibody|IgG2 antibody|IgG antibody|IgG3 antibody|IgG4 antibody|IgG2a antibody|IgG2b antibody|IgG2c antibody http://purl.obolibrary.org/obo/GO_0071736 GO:0071735 biolink:CellularComponent IgG immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json IgG2c|IgG2b|IgG2a|IgG4|IgG3|IgG2|IgG1 http://purl.obolibrary.org/obo/GO_0071735 GO:0071734 biolink:MolecularActivity biotin-[pyruvate-carboxylase] ligase activity Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase). EC:6.3.4.- go-plus.json biotin-[pyruvate carboxylase] synthetase activity|biotin-pyruvate carboxylase synthetase activity|biotin:apo-pyruvate-carboxylase ligase|biotin-pyruvate-carboxylase ligase activity|biotin-[pyruvate carboxylase] ligase activity http://purl.obolibrary.org/obo/GO_0071734 GO:0071733 biolink:BiologicalProcess obsolete transcriptional activation by promoter-enhancer looping OBSOLETE. The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter. go-plus.json long-range enhancer-promoter communication http://purl.obolibrary.org/obo/GO_0071733 CHEBI:59758 biolink:ChemicalSubstance omega-amino fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59758 GO:0071732 biolink:BiologicalProcess cellular response to nitric oxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071732 GO:0071731 biolink:BiologicalProcess response to nitric oxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071731 GO:0071730 biolink:BiologicalProcess beak formation The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. go-plus.json http://purl.obolibrary.org/obo/GO_0071730 GO:0007199 biolink:BiologicalProcess G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP). go-plus.json G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|GPCR signaling pathway via activation of guanylate cyclase activity|GPCR signaling pathway via cGMP second messenger|G protein signalling, coupled to cGMP nucleotide second messenger|G-protein signaling, coupled to cGMP nucleotide second messenger|G-protein signalling, coupled to cGMP nucleotide second messenger|guanylate cyclase-activating G-protein coupled receptor signaling pathway|G protein signaling, coupled to cGMP nucleotide second messenger http://purl.obolibrary.org/obo/GO_0007199 GO:0007198 biolink:BiologicalProcess adenylate cyclase-inhibiting serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json inhibition of adenylate cyclase activity by serotonin receptor signaling pathway|serotonin receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylate cyclase inhibiting pathway http://purl.obolibrary.org/obo/GO_0007198 GO:0007197 biolink:BiologicalProcess adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway|muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway|muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007197 GO:0007196 biolink:BiologicalProcess adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein-coupled glutamate receptor signaling pathway|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signalling pathway|metabotropic glutamate receptor, adenylate cyclase inhibiting pathway http://purl.obolibrary.org/obo/GO_0007196 GO:0032151 biolink:CellularComponent mitotic septin complex A heterooligomeric septin complex that acts during mitotic cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0032151 GO:0032150 biolink:BiologicalProcess ubiquinone biosynthetic process from chorismate The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate. go-plus.json http://purl.obolibrary.org/obo/GO_0032150 GO:0032159 biolink:CellularComponent septin cap A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol. go-plus.json http://purl.obolibrary.org/obo/GO_0032159 GO:0032158 biolink:CellularComponent septin band A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously. go-plus.json http://purl.obolibrary.org/obo/GO_0032158 GO:0032157 biolink:CellularComponent prospore contractile ring A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis. go-plus.json meiotic contractile ring|cytokinetic ring|actomyosin ring http://purl.obolibrary.org/obo/GO_0032157 GO:0032156 biolink:CellularComponent septin cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes. go-plus.json http://purl.obolibrary.org/obo/GO_0032156 GO:0032155 biolink:CellularComponent obsolete cell division site part OBSOLETE. Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell. go-plus.json cell division plane part http://purl.obolibrary.org/obo/GO_0032155 gocheck_do_not_annotate GO:0032154 biolink:CellularComponent cleavage furrow The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm. Wikipedia:Cleavage_furrow go-plus.json http://purl.obolibrary.org/obo/GO_0032154 GO:0032153 biolink:CellularComponent cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles. go-plus.json cell division plane http://purl.obolibrary.org/obo/GO_0032153 goslim_pir GO:0032152 biolink:CellularComponent meiotic septin complex A heterooligomeric septin complex that acts during meiotic cell division. go-plus.json http://purl.obolibrary.org/obo/GO_0032152 GO:0032149 biolink:BiologicalProcess response to rhamnose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus. go-plus.json response to L-rhamnose stimulus|response to rhamnose stimulus http://purl.obolibrary.org/obo/GO_0032149 GO:0032140 biolink:MolecularActivity single adenine insertion binding Binding to a double-stranded DNA region containing a single adenine insertion or a deletion that results in an unpaired adenine. go-plus.json http://purl.obolibrary.org/obo/GO_0032140 GO:0032148 biolink:BiologicalProcess activation of protein kinase B activity Any process that initiates the activity of the inactive enzyme protein kinase B. go-plus.json protein kinase B activation http://purl.obolibrary.org/obo/GO_0032148 GO:0032147 biolink:BiologicalProcess activation of protein kinase activity Any process that initiates the activity of an inactive protein kinase. go-plus.json protein kinase activation http://purl.obolibrary.org/obo/GO_0032147 GO:0032146 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032146 GO:0032145 biolink:MolecularActivity succinate-semialdehyde dehydrogenase binding Binding to succinate-semialdehyde dehydrogenase. go-plus.json succinic semialdehyde dehydrogenase binding http://purl.obolibrary.org/obo/GO_0032145 GO:0032144 biolink:CellularComponent 4-aminobutyrate transaminase complex A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity. go-plus.json ABAT complex|GABA transaminase complex|GABA-T complex http://purl.obolibrary.org/obo/GO_0032144 GO:0032143 biolink:MolecularActivity single thymine insertion binding Binding to a double-stranded DNA region containing a single thymine insertion or a deletion that results in an unpaired thymine. go-plus.json http://purl.obolibrary.org/obo/GO_0032143 GO:0032142 biolink:MolecularActivity single guanine insertion binding Binding to a double-stranded DNA region containing a single guanine insertion or a deletion that results in an unpaired guanine. go-plus.json http://purl.obolibrary.org/obo/GO_0032142 GO:0032141 biolink:MolecularActivity single cytosine insertion binding Binding to a double-stranded DNA region containing a single cytosine insertion or a deletion that results in an unpaired cytosine. go-plus.json http://purl.obolibrary.org/obo/GO_0032141 CHEBI:84729 biolink:ChemicalSubstance hydroxyindoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_84729 GO:0032139 biolink:MolecularActivity dinucleotide insertion or deletion binding Binding to a double-stranded DNA region containing a dinucleotide insertion or deletion. go-plus.json dinucleotide insertion binding http://purl.obolibrary.org/obo/GO_0032139 GO:0032138 biolink:MolecularActivity single base insertion or deletion binding Binding to a double-stranded DNA region containing a single base insertion or deletion. go-plus.json single base insertion binding http://purl.obolibrary.org/obo/GO_0032138 CHEBI:84726 biolink:ChemicalSubstance UDP-N-acetyl-alpha-D-muramoyl-L-alanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84726 CHEBI:84725 biolink:ChemicalSubstance UDP-beta-L-rhamnose go-plus.json http://purl.obolibrary.org/obo/CHEBI_84725 GO:0007179 biolink:BiologicalProcess transforming growth factor beta receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json transforming growth factor beta receptor signalling pathway|TGFbeta receptor signaling pathway|TGF-beta receptor signalling pathway|TGF-beta receptor signaling pathway|TGFbeta receptor signalling pathway http://purl.obolibrary.org/obo/GO_0007179 GO:0007178 biolink:BiologicalProcess transmembrane receptor protein serine/threonine kinase signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json transmembrane receptor protein serine/threonine kinase signalling pathway http://purl.obolibrary.org/obo/GO_0007178 GO:0007177 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007177 GO:0007176 biolink:BiologicalProcess regulation of epidermal growth factor-activated receptor activity Any process that modulates the frequency, rate or extent of EGF-activated receptor activity. go-plus.json regulation of EGF receptor activity|regulation of epidermal growth factor receptor activity|regulation of EGFR activity http://purl.obolibrary.org/obo/GO_0007176 GO:0007175 biolink:BiologicalProcess negative regulation of epidermal growth factor-activated receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity. go-plus.json downregulation of epidermal growth factor receptor activity|negative regulation of epidermal growth factor receptor activity|negative regulation of EGFR activity|down-regulation of epidermal growth factor receptor activity|inhibition of epidermal growth factor receptor activity|negative regulation of EGF receptor activity|EGF receptor downregulation|down regulation of epidermal growth factor receptor activity http://purl.obolibrary.org/obo/GO_0007175 GO:0007174 biolink:BiologicalProcess epidermal growth factor catabolic process The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor. go-plus.json EGF receptor ligand processing|intracellular EGF processing|receptor-mediated EGF processing|epidermal growth factor breakdown|epidermal growth factor ligand processing|EGF catabolism|EGF breakdown|epidermal growth factor catabolism http://purl.obolibrary.org/obo/GO_0007174 GO:0007184 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007184 GO:0007183 biolink:BiologicalProcess SMAD protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. go-plus.json SMAD protein heteromerization http://purl.obolibrary.org/obo/GO_0007183 CHEBI:60761 biolink:ChemicalSubstance floxuridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60761 chebi_ph7_3 GO:0007182 biolink:BiologicalProcess common-partner SMAD protein phosphorylation The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus. go-plus.json common partner SMAD protein phosphorylation|common-mediator SMAD protein phosphorylation|co-SMAD protein phosphorylation|common mediator SMAD protein phosphorylation http://purl.obolibrary.org/obo/GO_0007182 GO:0007181 biolink:BiologicalProcess transforming growth factor beta receptor complex assembly The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex. go-plus.json TGF-beta:type II receptor:type I receptor complex assembly|TGF-beta receptor complex assembly|TGFbeta receptor complex assembly http://purl.obolibrary.org/obo/GO_0007181 GO:0007180 biolink:BiologicalProcess obsolete transforming growth factor beta ligand binding to type II receptor OBSOLETE. (Was not defined before being made obsolete). go-plus.json TGFbeta ligand binding to type II receptor|TGF-beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type II receptor http://purl.obolibrary.org/obo/GO_0007180 GO:0032137 biolink:MolecularActivity guanine/thymine mispair binding Binding to a double-stranded DNA region containing a G/T mispair. go-plus.json thymine/guanine mispair binding|G/T mispair binding|T/G mispair binding http://purl.obolibrary.org/obo/GO_0032137 GO:0032136 biolink:MolecularActivity adenine/cytosine mispair binding Binding to a double-stranded DNA region containing an A/C mispair. go-plus.json cytosine/adenine mispair binding|C/A mispair binding|A/C mispair binding http://purl.obolibrary.org/obo/GO_0032136 GO:0032135 biolink:MolecularActivity DNA insertion or deletion binding Binding to a double-stranded DNA region containing an insertion or a deletion. go-plus.json insertion binding|DNA insertion binding http://purl.obolibrary.org/obo/GO_0032135 GO:0032134 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032134 GO:0032133 biolink:CellularComponent chromosome passenger complex A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin. go-plus.json CPC|chromosomal passenger complex|CPC complex http://purl.obolibrary.org/obo/GO_0032133 GO:0032132 biolink:MolecularActivity O6-alkylguanine-DNA binding Binding to an O6-alkylguanine adduct in DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0032132 GO:0032131 biolink:MolecularActivity alkylated DNA binding Binding to an alkylated residue in DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0032131 GO:0032130 biolink:BiologicalProcess medial membrane band assembly The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring. go-plus.json medial membrane band formation http://purl.obolibrary.org/obo/GO_0032130 GO:0032129 biolink:MolecularActivity histone deacetylase activity (H3-K9 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein. go-plus.json http://purl.obolibrary.org/obo/GO_0032129 GO:0032128 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032128 GO:0032127 biolink:CellularComponent dense core granule membrane The lipid bilayer surrounding a dense core granule. go-plus.json dense core vesicle membrane http://purl.obolibrary.org/obo/GO_0032127 CHEBI:84735 biolink:ChemicalSubstance algal metabolite go-plus.json http://purl.obolibrary.org/obo/CHEBI_84735 GO:0007189 biolink:BiologicalProcess adenylate cyclase-activating G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP). go-plus.json G protein signalling, adenylate cyclase activating pathway|activation of adenylate cyclase activity by G-protein signaling pathway|GPCR signaling pathway via activation of adenylate cyclase activity|positive regulation of adenylate cyclase activity by G-protein signalling pathway|activation of adenylate cyclase activity involved in G-protein signaling|G protein signalling, adenylyl cyclase activating pathway|G protein signaling, adenylate cyclase activating pathway|G-protein signaling, adenylate cyclase activating pathway|G-protein signaling, adenylyl cyclase activating pathway|G-protein signalling, adenylate cyclase activating pathway|positive regulation of adenylate cyclase activity by G-protein signaling pathway|GPCR signaling pathway via activation of adenylate cyclase|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|G-protein signalling, adenylyl cyclase activating pathway|adenylate cyclase-activating GPCR signaling pathway|G protein signaling, adenylyl cyclase activating pathway http://purl.obolibrary.org/obo/GO_0007189 CHEBI:84734 biolink:ChemicalSubstance Fe(III)-complexed siderophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_84734 GO:0007188 biolink:BiologicalProcess adenylate cyclase-modulating G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP). go-plus.json GPCR signaling pathway via modulation of adenylate cyclase activity|G protein signalling, coupled to cAMP nucleotide second messenger|adenylate cyclase-modulating GPCR signaling pathway|G protein signalling, coupled to cyclic AMP nucleotide second messenger|G-protein signaling, coupled to cyclic AMP nucleotide second messenger|G-protein signaling, coupled to cAMP nucleotide second messenger|G-protein signalling, coupled to cAMP nucleotide second messenger|G protein signaling, coupled to cAMP nucleotide second messenger|G-protein signalling, coupled to cyclic AMP nucleotide second messenger|GPCR signaling pathway via cAMP second messenger|G protein signaling, coupled to cyclic AMP nucleotide second messenger http://purl.obolibrary.org/obo/GO_0007188 CHEBI:84733 biolink:ChemicalSubstance dihexosylceramide sulfate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84733 CHEBI:84732 biolink:ChemicalSubstance sulfohexosyl ceramide(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84732 GO:0007187 biolink:BiologicalProcess G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. go-plus.json G protein signalling, coupled to cyclic nucleotide second messenger|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|G-protein signaling, coupled to cyclic nucleotide second messenger|G-protein signalling, coupled to cyclic nucleotide second messenger|G protein signaling, coupled to cyclic nucleotide second messenger|GPCR signaling pathway via cyclic nucleotide second messenger http://purl.obolibrary.org/obo/GO_0007187 GO:0007186 biolink:BiologicalProcess G protein-coupled receptor signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane. go-plus.json G protein coupled receptor protein signalling pathway|dimeric G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway via GPCR dimer|G protein coupled receptor protein signaling pathway|G-protein coupled receptor protein signal transduction|G-protein coupled receptor protein signaling pathway|GPCR signalling pathway|G-protein coupled receptor signalling pathway|dimeric G-protein coupled receptor signalling pathway|G-protein-coupled receptor protein signalling pathway|GPCR signaling pathway http://purl.obolibrary.org/obo/GO_0007186 goslim_drosophila GO:0007185 biolink:BiologicalProcess transmembrane receptor protein tyrosine phosphatase signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json transmembrane receptor protein tyrosine phosphatase signalling pathway http://purl.obolibrary.org/obo/GO_0007185 GO:0007195 biolink:BiologicalProcess adenylate cyclase-inhibiting dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json dopamine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by dopamine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007195 GO:0007194 biolink:BiologicalProcess negative regulation of adenylate cyclase activity Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity. go-plus.json down-regulation of adenylate cyclase activity|downregulation of adenylate cyclase activity|down regulation of adenylate cyclase activity|inhibition of adenylate cyclase activity|adenylate cyclase inhibitor|negative regulation of adenylyl cyclase activity http://purl.obolibrary.org/obo/GO_0007194 GO:0007193 biolink:BiologicalProcess adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json G protein signalling, adenylate cyclase inhibiting pathway|GPCR signaling pathway via inhibition of adenylate cyclase activity|inhibition of adenylate cyclase activity by G-protein signaling pathway|G protein signalling, adenylyl cyclase inhibiting pathway|G protein signaling, adenylate cyclase inhibiting pathway|G-protein signaling, adenylyl cyclase inhibiting pathway|G-protein signaling, adenylate cyclase inhibiting pathway|G-protein signalling, adenylate cyclase inhibiting pathway|adenylate cyclase-inhibiting GPCR signaling pathway|G-protein signalling, adenylyl cyclase inhibiting pathway|G protein signaling, adenylyl cyclase inhibiting pathway http://purl.obolibrary.org/obo/GO_0007193 GO:0007192 biolink:BiologicalProcess adenylate cyclase-activating serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). go-plus.json serotonin receptor, adenylate cyclase activating pathway|activation of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylyl cyclase activating pathway http://purl.obolibrary.org/obo/GO_0007192 GO:0007191 biolink:BiologicalProcess adenylate cyclase-activating dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). go-plus.json activation of adenylate cyclase activity by dopamine receptor signalling pathway|dopamine receptor, adenylate cyclase activating pathway|activation of adenylate cyclase activity by dopamine receptor signaling pathway|dopamine receptor, adenylyl cyclase activating pathway http://purl.obolibrary.org/obo/GO_0007191 GO:0007190 biolink:BiologicalProcess activation of adenylate cyclase activity Any process that initiates the activity of the inactive enzyme adenylate cyclase. go-plus.json adenylate cyclase activation|adenylate cyclase activator|adenylyl cyclase activation http://purl.obolibrary.org/obo/GO_0007190 GO:0032126 biolink:CellularComponent eisosome A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization. Wikipedia:Eisosome go-plus.json http://purl.obolibrary.org/obo/GO_0032126 GO:0032125 biolink:BiologicalProcess micronucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus. go-plus.json micronucleus organisation|micronuclear organization|micronuclear organization and biogenesis http://purl.obolibrary.org/obo/GO_0032125 GO:0032124 biolink:BiologicalProcess macronucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus. go-plus.json macronuclear organization and biogenesis|macronuclear organization|macronucleus organisation http://purl.obolibrary.org/obo/GO_0032124 GO:0032123 biolink:CellularComponent deep fiber Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm. go-plus.json deep fibre http://purl.obolibrary.org/obo/GO_0032123 GO:0032122 biolink:BiologicalProcess oral apparatus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans. go-plus.json oral apparatus organisation|stomatogenesis|oral apparatus organization and biogenesis|oral apparatus morphogenesis http://purl.obolibrary.org/obo/GO_0032122 GO:0032121 biolink:BiologicalProcess meiotic attachment of telomeric heterochromatin to spindle pole body The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation. go-plus.json attachment of telomeric chromatin to spindle pole body|attachment of telomeres to spindle pole body http://purl.obolibrary.org/obo/GO_0032121 GO:0032120 biolink:BiologicalProcess ascospore-type prospore membrane formation The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed. go-plus.json FSM assembly|ascospore-type prospore membrane assembly|forespore membrane biosynthesis|prospore membrane biogenesis|forespore membrane formation|FSM formation|FSM biosynthesis http://purl.obolibrary.org/obo/GO_0032120 GO:0032119 biolink:BiologicalProcess sequestering of zinc ion The process of binding or confining zinc ions such that they are separated from other components of a biological system. go-plus.json http://purl.obolibrary.org/obo/GO_0032119 GO:0032118 biolink:BiologicalProcess horsetail-astral microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis. go-plus.json horsetail-astral microtubule organization and biogenesis|horsetail-astral microtubule array organization|horsetail-astral microtubule organisation http://purl.obolibrary.org/obo/GO_0032118 GO:0032117 biolink:CellularComponent horsetail-astral microtubule array An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement. go-plus.json HAA http://purl.obolibrary.org/obo/GO_0032117 GO:0032116 biolink:CellularComponent SMC loading complex A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved. go-plus.json chromatin loading complex|SCC2/SCC4 loading complex|cohesin loading complex http://purl.obolibrary.org/obo/GO_0032116 GO:0007159 biolink:BiologicalProcess leukocyte cell-cell adhesion The attachment of a leukocyte to another cell via adhesion molecules. go-plus.json leukocyte adhesion|leukocyte cell adhesion http://purl.obolibrary.org/obo/GO_0007159 GO:0007158 biolink:BiologicalProcess neuron cell-cell adhesion The attachment of a neuron to another cell via adhesion molecules. go-plus.json neuron adhesion|neuronal cell adhesion http://purl.obolibrary.org/obo/GO_0007158 GO:0007157 biolink:BiologicalProcess heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. go-plus.json agglutination http://purl.obolibrary.org/obo/GO_0007157 GO:0007156 biolink:BiologicalProcess homophilic cell adhesion via plasma membrane adhesion molecules The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. go-plus.json http://purl.obolibrary.org/obo/GO_0007156 CHEBI:84745 biolink:ChemicalSubstance amiloride(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84745 GO:0007155 biolink:BiologicalProcess cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. Wikipedia:Cell_adhesion go-plus.json single organism cell adhesion|cell adhesion molecule activity http://purl.obolibrary.org/obo/GO_0007155 goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl GO:0007154 biolink:BiologicalProcess cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Wikipedia:Cell_signaling go-plus.json http://purl.obolibrary.org/obo/GO_0007154 goslim_plant|goslim_pir GO:0007153 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007153 GO:0007152 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007152 CHEBI:60784 biolink:ChemicalSubstance 3'-UMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60784 chebi_ph7_3 GO:0007162 biolink:BiologicalProcess negative regulation of cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. go-plus.json cell adhesion receptor inhibitor activity|down-regulation of cell adhesion|inhibition of cell adhesion|down regulation of cell adhesion|downregulation of cell adhesion http://purl.obolibrary.org/obo/GO_0007162 GO:0007161 biolink:BiologicalProcess calcium-independent cell-matrix adhesion The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction. go-plus.json calcium-independent cell adhesion molecule activity http://purl.obolibrary.org/obo/GO_0007161 CHEBI:60783 biolink:ChemicalSubstance nucleoside analogue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60783 GO:0007160 biolink:BiologicalProcess cell-matrix adhesion The binding of a cell to the extracellular matrix via adhesion molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0007160 CHEBI:3900 biolink:ChemicalSubstance costunolide go-plus.json http://purl.obolibrary.org/obo/CHEBI_3900 chebi_ph7_3 GO:0032115 biolink:MolecularActivity sorbose reductase activity Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction. RHEA:14609|KEGG_REACTION:R07346|MetaCyc:1.1.1.289-RXN|EC:1.1.1.289 go-plus.json Sou1p|D-glucitol:NADP+ oxidoreductase activity http://purl.obolibrary.org/obo/GO_0032115 GO:0032114 biolink:BiologicalProcess regulation of glucose-6-phosphatase activity Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032114 GO:0032113 biolink:BiologicalProcess regulation of carbohydrate phosphatase activity Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate. go-plus.json http://purl.obolibrary.org/obo/GO_0032113 GO:0032112 biolink:BiologicalProcess negative regulation of protein histidine kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity. go-plus.json down-regulation of protein histidine kinase activity|inhibition of protein histidine kinase activity|protein histidine kinase inhibitor|down regulation of protein histidine kinase activity|downregulation of protein histidine kinase activity http://purl.obolibrary.org/obo/GO_0032112 GO:0032111 biolink:BiologicalProcess activation of protein histidine kinase activity Any process that initiates the activity of an inactive protein histidine kinase. go-plus.json protein histidine kinase activator http://purl.obolibrary.org/obo/GO_0032111 GO:0032110 biolink:BiologicalProcess regulation of protein histidine kinase activity Any process that modulates the frequency, rate or extent of protein histidine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0032110 GO:0032109 biolink:BiologicalProcess positive regulation of response to nutrient levels Any process that activates or increases the frequency, rate or extent of a response to nutrient levels. go-plus.json up regulation of response to nutrient levels|activation of response to nutrient levels|stimulation of response to nutrient levels|up-regulation of response to nutrient levels|upregulation of response to nutrient levels http://purl.obolibrary.org/obo/GO_0032109 GO:0032108 biolink:BiologicalProcess negative regulation of response to nutrient levels Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels. go-plus.json downregulation of response to nutrient levels|down-regulation of response to nutrient levels|inhibition of response to nutrient levels|down regulation of response to nutrient levels http://purl.obolibrary.org/obo/GO_0032108 GO:0032107 biolink:BiologicalProcess regulation of response to nutrient levels Any process that modulates the frequency, rate or extent of a response to nutrient levels. go-plus.json http://purl.obolibrary.org/obo/GO_0032107 GO:0032106 biolink:BiologicalProcess positive regulation of response to extracellular stimulus Any process that activates, maintains or increases the rate of a response to an extracellular stimulus. go-plus.json stimulation of response to extracellular stimulus|up-regulation of response to extracellular stimulus|activation of response to extracellular stimulus|up regulation of response to extracellular stimulus|upregulation of response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0032106 GO:0032105 biolink:BiologicalProcess negative regulation of response to extracellular stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus. go-plus.json down-regulation of response to extracellular stimulus|downregulation of response to extracellular stimulus|down regulation of response to extracellular stimulus|inhibition of response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0032105 GO:0007169 biolink:BiologicalProcess transmembrane receptor protein tyrosine kinase signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json transmembrane receptor protein tyrosine kinase signalling pathway http://purl.obolibrary.org/obo/GO_0007169 GO:0007168 biolink:BiologicalProcess receptor guanylyl cyclase signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json receptor guanylyl cyclase signalling pathway http://purl.obolibrary.org/obo/GO_0007168 GO:0007167 biolink:BiologicalProcess enzyme linked receptor protein signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json enzyme linked receptor protein signalling pathway http://purl.obolibrary.org/obo/GO_0007167 CHEBI:84756 biolink:ChemicalSubstance 2-deoxy-D-glucopyranose 6-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84756 GO:0007166 biolink:BiologicalProcess cell surface receptor signaling pathway A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json cell surface receptor linked signalling pathway|cell surface receptor linked signal transduction|cell surface receptor linked signaling pathway http://purl.obolibrary.org/obo/GO_0007166 goslim_drosophila CHEBI:84755 biolink:ChemicalSubstance 2-deoxy-D-glucopyranose go-plus.json http://purl.obolibrary.org/obo/CHEBI_84755 chebi_ph7_3 CHEBI:3918 biolink:ChemicalSubstance crocetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3918 GO:0007165 biolink:BiologicalProcess signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. Wikipedia:Signal_transduction go-plus.json signalling cascade|signal transduction by protein phosphorylation|signaling cascade|signal transduction by cis-phosphorylation|signal transduction by trans-phosphorylation|signal transduction by conformational transition|signalling pathway|signaling pathway http://purl.obolibrary.org/obo/GO_0007165 goslim_chembl|goslim_candida|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic GO:0007164 biolink:BiologicalProcess establishment of tissue polarity Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. go-plus.json http://purl.obolibrary.org/obo/GO_0007164 GO:0007163 biolink:BiologicalProcess establishment or maintenance of cell polarity Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. go-plus.json cell polarity|establishment and/or maintenance of cell polarity|establishment and/or maintenance of cell polarization http://purl.obolibrary.org/obo/GO_0007163 goslim_pombe GO:0007173 biolink:BiologicalProcess epidermal growth factor receptor signaling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json ERBB1 signaling pathway|EGF receptor signaling pathway|epidermal growth factor receptor signalling pathway|EGFR signaling pathway|receptor tyrosine-protein kinase erbB-1 signaling pathway|EGF receptor signalling pathway http://purl.obolibrary.org/obo/GO_0007173 GO:0007172 biolink:BiologicalProcess signal complex assembly The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. go-plus.json signal complex formation http://purl.obolibrary.org/obo/GO_0007172 GO:0007171 biolink:BiologicalProcess activation of transmembrane receptor protein tyrosine kinase activity Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. go-plus.json transmembrane receptor protein tyrosine kinase activation|transmembrane receptor protein tyrosine kinase dimerization http://purl.obolibrary.org/obo/GO_0007171 GO:0007170 biolink:BiologicalProcess obsolete transmembrane receptor protein tyrosine kinase ligand binding OBSOLETE. (Was not defined before being made obsolete). go-plus.json transmembrane receptor protein tyrosine kinase ligand binding http://purl.obolibrary.org/obo/GO_0007170 CHEBI:60798 biolink:ChemicalSubstance excitatory amino acid antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_60798 GO:0032104 biolink:BiologicalProcess regulation of response to extracellular stimulus Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032104 GO:0032103 biolink:BiologicalProcess positive regulation of response to external stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. go-plus.json stimulation of response to external stimulus|up-regulation of response to external stimulus|upregulation of response to external stimulus|up regulation of response to external stimulus|activation of response to external stimulus http://purl.obolibrary.org/obo/GO_0032103 gocheck_do_not_manually_annotate GO:0032102 biolink:BiologicalProcess negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. go-plus.json down-regulation of response to external stimulus|inhibition of response to external stimulus|down regulation of response to external stimulus|downregulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0032102 gocheck_do_not_manually_annotate GO:0032101 biolink:BiologicalProcess regulation of response to external stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032101 gocheck_do_not_manually_annotate GO:0032100 biolink:BiologicalProcess positive regulation of appetite Any process that increases appetite. go-plus.json positive regulation of hunger|up regulation of appetite|appetite stimulation|upregulation of appetite|stimulation of appetite|up-regulation of appetite|activation of appetite http://purl.obolibrary.org/obo/GO_0032100 GO:0007139 biolink:BiologicalProcess meiotic telophase II The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. go-plus.json http://purl.obolibrary.org/obo/GO_0007139 gocheck_do_not_annotate GO:0007138 biolink:BiologicalProcess meiotic anaphase II The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II. go-plus.json http://purl.obolibrary.org/obo/GO_0007138 gocheck_do_not_annotate GO:0046701 biolink:BiologicalProcess insecticide catabolic process The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects. go-plus.json insecticide degradation|insecticide breakdown|insecticide catabolism http://purl.obolibrary.org/obo/GO_0046701 GO:0007137 biolink:BiologicalProcess meiotic metaphase II The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II. go-plus.json http://purl.obolibrary.org/obo/GO_0007137 gocheck_do_not_annotate GO:0046700 biolink:BiologicalProcess heterocycle catabolic process The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). go-plus.json heterocycle degradation|heterocycle breakdown|heterocycle catabolism http://purl.obolibrary.org/obo/GO_0046700 GO:0007136 biolink:BiologicalProcess meiotic prophase II The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0007136 gocheck_do_not_annotate GO:0007135 biolink:BiologicalProcess meiosis II The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. Wikipedia:Meiosis#Meiosis_II go-plus.json meiosis II nuclear division http://purl.obolibrary.org/obo/GO_0007135 GO:0007134 biolink:BiologicalProcess meiotic telophase I The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. go-plus.json http://purl.obolibrary.org/obo/GO_0007134 gocheck_do_not_annotate GO:0007133 biolink:BiologicalProcess meiotic anaphase I The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0007133 gocheck_do_not_annotate GO:0007132 biolink:BiologicalProcess meiotic metaphase I The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I. go-plus.json http://purl.obolibrary.org/obo/GO_0007132 gocheck_do_not_annotate GO:0007131 biolink:BiologicalProcess reciprocal meiotic recombination The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity. go-plus.json gene conversion with reciprocal crossover|female meiotic recombination http://purl.obolibrary.org/obo/GO_0007131 GO:0007130 biolink:BiologicalProcess synaptonemal complex assembly The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination. go-plus.json synaptonemal complex formation http://purl.obolibrary.org/obo/GO_0007130 GO:0007140 biolink:BiologicalProcess male meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. go-plus.json male nuclear division|male meiosis http://purl.obolibrary.org/obo/GO_0007140 GO:0046709 biolink:BiologicalProcess IDP catabolic process The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate. go-plus.json IDP degradation|IDP catabolism|IDP breakdown http://purl.obolibrary.org/obo/GO_0046709 GO:0046708 biolink:BiologicalProcess IDP biosynthetic process The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate. go-plus.json IDP biosynthesis|IDP anabolism|IDP synthesis|IDP formation http://purl.obolibrary.org/obo/GO_0046708 CHEBI:84760 biolink:ChemicalSubstance 2-deoxy-D-glucopyranose 6-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84760 chebi_ph7_3 GO:0046707 biolink:BiologicalProcess IDP metabolic process The chemical reactions and pathways involving IDP, inosine 5'-diphosphate. go-plus.json IDP metabolism http://purl.obolibrary.org/obo/GO_0046707 GO:0046706 biolink:BiologicalProcess CDP catabolic process The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate. go-plus.json CDP catabolism|CDP degradation|CDP breakdown http://purl.obolibrary.org/obo/GO_0046706 GO:0046705 biolink:BiologicalProcess CDP biosynthetic process The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate. go-plus.json CDP synthesis|CDP formation|CDP biosynthesis|CDP anabolism http://purl.obolibrary.org/obo/GO_0046705 GO:0046704 biolink:BiologicalProcess CDP metabolic process The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate. go-plus.json CDP metabolism http://purl.obolibrary.org/obo/GO_0046704 GO:0046703 biolink:MolecularActivity natural killer cell lectin-like receptor binding Binding to a lectin-like natural killer cell receptor. go-plus.json NKG2D receptor binding|NK cell lectin-like receptor binding|KLRC4 receptor binding http://purl.obolibrary.org/obo/GO_0046703 GO:0046702 biolink:MolecularActivity galactoside 6-L-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside. go-plus.json http://purl.obolibrary.org/obo/GO_0046702 GO:0007149 biolink:BiologicalProcess obsolete colony morphology OBSOLETE. (Was not defined before being made obsolete). go-plus.json colony morphology http://purl.obolibrary.org/obo/GO_0007149 GO:0046712 biolink:BiologicalProcess GDP catabolic process The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate. go-plus.json GDP catabolism|GDP degradation|GDP breakdown http://purl.obolibrary.org/obo/GO_0046712 GO:0007148 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007148 GO:0046711 biolink:BiologicalProcess GDP biosynthetic process The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate. go-plus.json GDP anabolism|GDP synthesis|GDP formation|GDP biosynthesis http://purl.obolibrary.org/obo/GO_0046711 GO:0007147 biolink:BiologicalProcess female meiosis II The cell cycle process in which the second meiotic division occurs in the female germline. go-plus.json female meiosis II nuclear division http://purl.obolibrary.org/obo/GO_0007147 GO:0046710 biolink:BiologicalProcess GDP metabolic process The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate. go-plus.json GDP metabolism http://purl.obolibrary.org/obo/GO_0046710 GO:0007146 biolink:BiologicalProcess meiotic recombination nodule assembly During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0007146 GO:0007145 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007145 GO:0007144 biolink:BiologicalProcess female meiosis I The cell cycle process in which the first meiotic division occurs in the female germline. go-plus.json female meiosis I nuclear division http://purl.obolibrary.org/obo/GO_0007144 GO:0007143 biolink:BiologicalProcess female meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. go-plus.json female meiosis|female meiotic division http://purl.obolibrary.org/obo/GO_0007143 GO:0007142 biolink:BiologicalProcess male meiosis II A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline. go-plus.json male meiosis II nuclear division http://purl.obolibrary.org/obo/GO_0007142 GO:0007141 biolink:BiologicalProcess male meiosis I A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline. go-plus.json male meiosis I nuclear division http://purl.obolibrary.org/obo/GO_0007141 GO:0007151 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007151 GO:0046719 biolink:BiologicalProcess regulation by virus of viral protein levels in host cell Any virus-mediated process that modulates the levels of viral proteins in a cell. go-plus.json regulation of viral protein levels http://purl.obolibrary.org/obo/GO_0046719 GO:0007150 biolink:BiologicalProcess obsolete growth pattern OBSOLETE. A process whereby cells develop a specific morphology under a specific set of circumstances. go-plus.json growth pattern http://purl.obolibrary.org/obo/GO_0007150 GO:0046718 biolink:BiologicalProcess viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm. VZ:936 go-plus.json virion penetration into host cell|phage translocation|virus entry into host cell|entry of virus into host cell|viral penetration|virion penetration http://purl.obolibrary.org/obo/GO_0046718 goslim_metagenomics GO:0046717 biolink:BiologicalProcess acid secretion The controlled release of acid by a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0046717 GO:0046716 biolink:BiologicalProcess muscle cell cellular homeostasis The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. go-plus.json muscle homeostasis|muscle fiber maintenance http://purl.obolibrary.org/obo/GO_0046716 GO:0046715 biolink:MolecularActivity active borate transmembrane transporter activity Enables the transport of borate across a membrane against the concentration gradient. go-plus.json efflux-type boron transporter|efflux-type borate transporter|borate transmembrane transporter activity|borate uptake transmembrane transporter activity|boron uptake transmembrane transporter activity|boron transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046715 GO:0046714 biolink:MolecularActivity borate binding Binding to borate, the anion (BO3)3-. go-plus.json boron binding http://purl.obolibrary.org/obo/GO_0046714 GO:0046713 biolink:BiologicalProcess borate transport The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals. go-plus.json boron transport http://purl.obolibrary.org/obo/GO_0046713 GO:1900598 biolink:BiologicalProcess demethylkotanin catabolic process The chemical reactions and pathways resulting in the breakdown of demethylkotanin. go-plus.json demethylkotanin catabolism|demethylkotanin degradation|demethylkotanin breakdown http://purl.obolibrary.org/obo/GO_1900598 GO:1900597 biolink:BiologicalProcess demethylkotanin metabolic process The chemical reactions and pathways involving demethylkotanin. go-plus.json demethylkotanin metabolism http://purl.obolibrary.org/obo/GO_1900597 GO:1900599 biolink:BiologicalProcess demethylkotanin biosynthetic process The chemical reactions and pathways resulting in the formation of demethylkotanin. go-plus.json demethylkotanin biosynthesis|demethylkotanin anabolism|demethylkotanin synthesis|demethylkotanin formation http://purl.obolibrary.org/obo/GO_1900599 GO:1900594 biolink:BiologicalProcess (+)-kotanin metabolic process The chemical reactions and pathways involving (+)-kotanin. go-plus.json (+)-kotanin metabolism http://purl.obolibrary.org/obo/GO_1900594 GO:1900593 biolink:BiologicalProcess violaceol II biosynthetic process The chemical reactions and pathways resulting in the formation of violaceol II. go-plus.json violaceol II anabolism|violaceol II synthesis|violaceol II formation|violaceol II biosynthesis http://purl.obolibrary.org/obo/GO_1900593 GO:1900596 biolink:BiologicalProcess (+)-kotanin biosynthetic process The chemical reactions and pathways resulting in the formation of (+)-kotanin. go-plus.json (+)-kotanin synthesis|(+)-kotanin formation|(+)-kotanin anabolism|(+)-kotanin biosynthesis http://purl.obolibrary.org/obo/GO_1900596 GO:1900595 biolink:BiologicalProcess (+)-kotanin catabolic process The chemical reactions and pathways resulting in the breakdown of (+)-kotanin. go-plus.json (+)-kotanin degradation|(+)-kotanin breakdown|(+)-kotanin catabolism http://purl.obolibrary.org/obo/GO_1900595 CHEBI:3941 biolink:ChemicalSubstance cucurbitacin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_3941 chebi_ph7_3 CHEBI:35704 biolink:ChemicalSubstance N(2)-acetyl-L-lysine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35704 CHEBI:35703 biolink:ChemicalSubstance xenobiotic go-plus.json http://purl.obolibrary.org/obo/CHEBI_35703 CHEBI:35705 biolink:ChemicalSubstance immunosuppressive agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35705 CHEBI:35709 biolink:ChemicalSubstance thujane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35709 chebi_ph7_3 CHEBI:35701 biolink:ChemicalSubstance ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_35701 GO:0032096 biolink:BiologicalProcess negative regulation of response to food Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus. go-plus.json down regulation of response to food|inhibition of response to food|down-regulation of response to food|downregulation of response to food http://purl.obolibrary.org/obo/GO_0032096 GO:0032095 biolink:BiologicalProcess regulation of response to food Any process that modulates the frequency, rate or extent of a response to a food stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0032095 GO:0032094 biolink:BiologicalProcess response to food Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat. go-plus.json http://purl.obolibrary.org/obo/GO_0032094 GO:0032093 biolink:MolecularActivity SAM domain binding Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes. go-plus.json Sterile Alpha Motif domain binding http://purl.obolibrary.org/obo/GO_0032093 GO:0032092 biolink:BiologicalProcess positive regulation of protein binding Any process that activates or increases the frequency, rate or extent of protein binding. go-plus.json up regulation of protein binding|activation of protein binding|stimulation of protein binding|up-regulation of protein binding|upregulation of protein binding http://purl.obolibrary.org/obo/GO_0032092 GO:0032091 biolink:BiologicalProcess negative regulation of protein binding Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. go-plus.json downregulation of protein binding|down-regulation of protein binding|inhibition of protein binding|down regulation of protein binding http://purl.obolibrary.org/obo/GO_0032091 GO:0032090 biolink:MolecularActivity Pyrin domain binding Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain. go-plus.json PAAD domain binding|DAPIN domain binding http://purl.obolibrary.org/obo/GO_0032090 GO:0032099 biolink:BiologicalProcess negative regulation of appetite Any process that reduces appetite. go-plus.json appetite suppression|negative regulation of hunger|down-regulation of appetite|downregulation of appetite|down regulation of appetite|inhibition of appetite http://purl.obolibrary.org/obo/GO_0032099 GO:0032098 biolink:BiologicalProcess regulation of appetite Any process which modulates appetite, the desire or physical craving for food. go-plus.json regulation of hunger http://purl.obolibrary.org/obo/GO_0032098 GO:0032097 biolink:BiologicalProcess positive regulation of response to food Any process that activates, maintains, or increases the rate of a response to a food stimulus. go-plus.json upregulation of response to food|stimulation of response to food|up-regulation of response to food|activation of response to food|up regulation of response to food http://purl.obolibrary.org/obo/GO_0032097 GO:0032085 biolink:BiologicalProcess regulation of type II site-specific deoxyribonuclease activity Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity. go-plus.json regulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease regulator|type II restriction enzyme regulator http://purl.obolibrary.org/obo/GO_0032085 GO:0032084 biolink:BiologicalProcess regulation of type I site-specific deoxyribonuclease activity Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity. go-plus.json type I restriction endodeoxyribonuclease regulator|regulation of type I restriction endodeoxyribonuclease activity|type I restriction enzyme regulator http://purl.obolibrary.org/obo/GO_0032084 GO:0032083 biolink:BiologicalProcess negative regulation of type IV site-specific deoxyribonuclease activity Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity. go-plus.json downregulation of type IV restriction endodeoxyribonuclease activity|type IV restriction enzyme inhibitor|down regulation of type IV restriction endodeoxyribonuclease activity|inhibition of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease inhibitor|negative regulation of type IV restriction endodeoxyribonuclease activity|down-regulation of type IV restriction endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032083 GO:0032082 biolink:BiologicalProcess negative regulation of type III site-specific deoxyribonuclease activity Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity. go-plus.json down-regulation of type III restriction endodeoxyribonuclease activity|inhibition of type III restriction endodeoxyribonuclease activity|type III restriction enzyme inhibitor|down regulation of type III restriction endodeoxyribonuclease activity|type III restriction endodeoxyribonuclease inhibitor|negative regulation of type III restriction endodeoxyribonuclease activity|downregulation of type III restriction endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032082 GO:0032081 biolink:BiologicalProcess negative regulation of type II site-specific deoxyribonuclease activity Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity. go-plus.json down-regulation of type II restriction endodeoxyribonuclease activity|downregulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease inhibitor|type II restriction enzyme inhibitor|down regulation of type II restriction endodeoxyribonuclease activity|inhibition of type II restriction endodeoxyribonuclease activity|negative regulation of type II restriction endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032081 GO:0032080 biolink:BiologicalProcess negative regulation of type I site-specific deoxyribonuclease activity Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity. go-plus.json down-regulation of type I restriction endodeoxyribonuclease activity|inhibition of type I restriction endodeoxyribonuclease activity|type I restriction enzyme inhibitor|down regulation of type I restriction endodeoxyribonuclease activity|type I restriction endodeoxyribonuclease inhibitor|negative regulation of type I restriction endodeoxyribonuclease activity|downregulation of type I restriction endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032080 GO:0032089 biolink:MolecularActivity NACHT domain binding Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs. go-plus.json http://purl.obolibrary.org/obo/GO_0032089 GO:0032088 biolink:BiologicalProcess negative regulation of NF-kappaB transcription factor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. go-plus.json inhibition of NF-kappaB transcription factor|NF-kappaB inhibitor http://purl.obolibrary.org/obo/GO_0032088 GO:0032087 biolink:BiologicalProcess regulation of type IV site-specific deoxyribonuclease activity Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity. go-plus.json type IV restriction enzyme regulator|regulation of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease regulator http://purl.obolibrary.org/obo/GO_0032087 GO:0032086 biolink:BiologicalProcess regulation of type III site-specific deoxyribonuclease activity Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity. go-plus.json type III restriction endodeoxyribonuclease regulator|regulation of type III restriction endoribonuclease activity|type III restriction enzyme regulator http://purl.obolibrary.org/obo/GO_0032086 GO:0032074 biolink:BiologicalProcess negative regulation of nuclease activity Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids. go-plus.json down-regulation of nuclease activity|inhibition of nuclease activity|nuclease inhibitor|down regulation of nuclease activity|downregulation of nuclease activity http://purl.obolibrary.org/obo/GO_0032074 GO:0032073 biolink:BiologicalProcess negative regulation of restriction endodeoxyribonuclease activity Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. go-plus.json restriction enzyme inhibitor|down regulation of restriction endodeoxyribonuclease activity|inhibition of restriction endodeoxyribonuclease activity|restriction alleviation|restriction endodeoxyribonuclease inhibitor|down-regulation of restriction endodeoxyribonuclease activity|downregulation of restriction endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032073 GO:0032072 biolink:BiologicalProcess regulation of restriction endodeoxyribonuclease activity Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. go-plus.json http://purl.obolibrary.org/obo/GO_0032072 GO:0032071 biolink:BiologicalProcess regulation of endodeoxyribonuclease activity Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. go-plus.json endodeoxyribonuclease regulator http://purl.obolibrary.org/obo/GO_0032071 GO:0032070 biolink:BiologicalProcess regulation of deoxyribonuclease activity Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. go-plus.json deoxyribonuclease regulator|DNase regulator http://purl.obolibrary.org/obo/GO_0032070 GO:0032079 biolink:BiologicalProcess positive regulation of endodeoxyribonuclease activity Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. go-plus.json stimulation of endodeoxyribonuclease activity|up-regulation of endodeoxyribonuclease activity|activation of endodeoxyribonuclease activity|endodeoxyribonuclease activator|up regulation of endodeoxyribonuclease activity|upregulation of endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032079 GO:0032078 biolink:BiologicalProcess negative regulation of endodeoxyribonuclease activity Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. go-plus.json down-regulation of endodeoxyribonuclease activity|downregulation of endodeoxyribonuclease activity|down regulation of endodeoxyribonuclease activity|endodeoxyribonuclease inhibitor|inhibition of endodeoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032078 GO:0032077 biolink:BiologicalProcess positive regulation of deoxyribonuclease activity Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. go-plus.json DNase activator|up regulation of deoxyribonuclease activity|upregulation of deoxyribonuclease activity|stimulation of deoxyribonuclease activity|up-regulation of deoxyribonuclease activity|activation of deoxyribonuclease activity|deoxyribonuclease activator http://purl.obolibrary.org/obo/GO_0032077 GO:0032076 biolink:BiologicalProcess negative regulation of deoxyribonuclease activity Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. go-plus.json deoxyribonuclease inhibitor|downregulation of deoxyribonuclease activity|down regulation of deoxyribonuclease activity|DNase inhibitor|inhibition of deoxyribonuclease activity|down-regulation of deoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0032076 GO:0032075 biolink:BiologicalProcess positive regulation of nuclease activity Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. go-plus.json up regulation of nuclease activity|activation of nuclease activity|stimulation of nuclease activity|nuclease activator|up-regulation of nuclease activity|upregulation of nuclease activity http://purl.obolibrary.org/obo/GO_0032075 GO:0032063 biolink:BiologicalProcess negative regulation of translational initiation in response to osmotic stress Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json down regulation of translation initiation in response to osmotic stress|inhibition of translation initiation in response to osmotic stress|down-regulation of translation initiation in response to osmotic stress|downregulation of translation initiation in response to osmotic stress http://purl.obolibrary.org/obo/GO_0032063 GO:0032062 biolink:BiologicalProcess positive regulation of translation in response to osmotic stress Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json up regulation of translation in response to osmotic stress|activation of translation in response to osmotic stress|stimulation of translation in response to osmotic stress|up-regulation of translation in response to osmotic stress|upregulation of translation in response to osmotic stress http://purl.obolibrary.org/obo/GO_0032062 GO:0032061 biolink:BiologicalProcess negative regulation of translation in response to osmotic stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json downregulation of translation in response to osmotic stress|down-regulation of translation in response to osmotic stress|inhibition of translation in response to osmotic stress|down regulation of translation in response to osmotic stress http://purl.obolibrary.org/obo/GO_0032061 GO:0032060 biolink:BiologicalProcess bleb assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. go-plus.json plasma membrane blebbing|cell blebbing|plasma membrane bleb assembly|membrane blebbing|blebbing http://purl.obolibrary.org/obo/GO_0032060 GO:0032069 biolink:BiologicalProcess regulation of nuclease activity Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. go-plus.json nuclease regulator activity http://purl.obolibrary.org/obo/GO_0032069 GO:0032068 biolink:CellularComponent type IV site-specific deoxyribonuclease complex A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation. go-plus.json type IV restriction enzyme complex http://purl.obolibrary.org/obo/GO_0032068 GO:0032067 biolink:MolecularActivity type IV site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated). go-plus.json type IV restriction enzyme activity http://purl.obolibrary.org/obo/GO_0032067 GO:0032066 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032066 GO:0032065 biolink:BiologicalProcess maintenance of protein location in cell cortex A process in which a protein or protein complex is maintained in a specific location in the cell cortex. go-plus.json maintenance of protein location in cell cortex|cortical protein anchoring http://purl.obolibrary.org/obo/GO_0032065 CHEBI:3992 biolink:ChemicalSubstance cyclic ketone go-plus.json http://purl.obolibrary.org/obo/CHEBI_3992 GO:0032064 biolink:BiologicalProcess positive regulation of translational initiation in response to osmotic stress Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. go-plus.json upregulation of translation initiation in response to osmotic stress|stimulation of translation initiation in response to osmotic stress|up-regulation of translation initiation in response to osmotic stress|activation of translation initiation in response to osmotic stress|up regulation of translation initiation in response to osmotic stress http://purl.obolibrary.org/obo/GO_0032064 NCBITaxon:367110 biolink:OrganismalEntity Neurospora crassa OR74A go-plus.json Neurospora crassa 74-OR23-1V A|Neurospora crassa N150|Neurospora crassa FGSC 9013|Neurospora crassa 74-OR23-1VA|Neurospora crassa FGSC 2489 http://purl.obolibrary.org/obo/NCBITaxon_367110 GO:0007099 biolink:BiologicalProcess centriole replication The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0. go-plus.json ciliary basal body duplication|centriole duplication|microtubule basal body duplication http://purl.obolibrary.org/obo/GO_0007099 GO:0007098 biolink:BiologicalProcess centrosome cycle The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle. go-plus.json centrosome organization and biogenesis|centrosome organisation|centrosome organization http://purl.obolibrary.org/obo/GO_0007098 GO:0007097 biolink:BiologicalProcess nuclear migration The directed movement of the nucleus to a specific location within a cell. go-plus.json positioning of nucleus|establishment of localization of nucleus|nucleus positioning|nuclear movement|establishment of nucleus localisation|establishment of nucleus localization|establishment of position of nucleus|nucleus migration|establishment of cell nucleus localization|nuclear positioning http://purl.obolibrary.org/obo/GO_0007097 goslim_aspergillus GO:0032052 biolink:MolecularActivity bile acid binding Binding to a bile acid, a steroid carboxylic acids occurring in bile. go-plus.json http://purl.obolibrary.org/obo/GO_0032052 GO:0032051 biolink:MolecularActivity clathrin light chain binding Binding to a clathrin light chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032051 GO:0032050 biolink:MolecularActivity clathrin heavy chain binding Binding to a clathrin heavy chain. go-plus.json http://purl.obolibrary.org/obo/GO_0032050 CHEBI:3962 biolink:ChemicalSubstance curcumin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3962 chebi_ph7_3 CHEBI:60721 biolink:ChemicalSubstance all-trans-decaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60721 chebi_ph7_3 CHEBI:60724 biolink:ChemicalSubstance dipalmitoyl phosphatidylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_60724 GO:0032059 biolink:CellularComponent bleb A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. Wikipedia:Bleb_(cell_biology) go-plus.json plasma membrane bleb http://purl.obolibrary.org/obo/GO_0032059 goslim_pir GO:0032058 biolink:BiologicalProcess positive regulation of translational initiation in response to stress Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress. go-plus.json up regulation of translation initiation in response to stress|upregulation of translation initiation in response to stress|stimulation of translation initiation in response to stress|up-regulation of translation initiation in response to stress|activation of translation initiation in response to stress http://purl.obolibrary.org/obo/GO_0032058 GO:0032057 biolink:BiologicalProcess negative regulation of translational initiation in response to stress Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. go-plus.json down-regulation of translation initiation in response to stress|downregulation of translation initiation in response to stress|down regulation of translation initiation in response to stress|inhibition of translation initiation in response to stress http://purl.obolibrary.org/obo/GO_0032057 GO:0032056 biolink:BiologicalProcess positive regulation of translation in response to stress Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. go-plus.json upregulation of translation in response to stress|up regulation of translation in response to stress|activation of translation in response to stress|stimulation of translation in response to stress|up-regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0032056 GO:0032055 biolink:BiologicalProcess negative regulation of translation in response to stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress. go-plus.json down regulation of translation in response to stress|downregulation of translation in response to stress|down-regulation of translation in response to stress|inhibition of translation in response to stress http://purl.obolibrary.org/obo/GO_0032055 GO:0032054 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032054 GO:0032053 biolink:BiologicalProcess ciliary basal body organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum). go-plus.json microtubule basal body organisation|microtubule basal body organization|microtubule basal body organization and biogenesis http://purl.obolibrary.org/obo/GO_0032053 GO:0032041 biolink:MolecularActivity NAD-dependent histone deacetylase activity (H3-K14 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein. EC:3.5.1.98 go-plus.json http://purl.obolibrary.org/obo/GO_0032041 GO:0032040 biolink:CellularComponent small-subunit processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. go-plus.json small subunit processome|SSU processome http://purl.obolibrary.org/obo/GO_0032040 CHEBI:60732 biolink:ChemicalSubstance guanosine 3'-monophosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60732 chebi_ph7_3 CHEBI:3978 biolink:ChemicalSubstance cyanin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3978 GO:0032049 biolink:BiologicalProcess cardiolipin biosynthetic process The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. MetaCyc:PWY-5269 go-plus.json diphosphatidylglycerol biosynthesis|diphosphatidylglycerol biosynthetic process http://purl.obolibrary.org/obo/GO_0032049 GO:0032048 biolink:BiologicalProcess cardiolipin metabolic process The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. go-plus.json diphosphatidylglycerol metabolic process|diphosphatidylglycerol metabolism|cardiolipin metabolism http://purl.obolibrary.org/obo/GO_0032048 GO:0032047 biolink:CellularComponent mitosome A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria. Wikipedia:Mitosome go-plus.json crypton http://purl.obolibrary.org/obo/GO_0032047 GO:0032046 biolink:CellularComponent micropexophagy-specific membrane apparatus A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole. go-plus.json MIPA|micropexophagic apparatus http://purl.obolibrary.org/obo/GO_0032046 GO:0032045 biolink:CellularComponent guanyl-nucleotide exchange factor complex A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase. go-plus.json http://purl.obolibrary.org/obo/GO_0032045 GO:0032044 biolink:CellularComponent DSIF complex A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes. go-plus.json Spt5-Spt4 complex|Spt4-Spt5 complex|DRB sensitivity inducing factor complex|5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex http://purl.obolibrary.org/obo/GO_0032044 GO:0032043 biolink:BiologicalProcess mitochondrial DNA catabolic process The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA. go-plus.json mitochondrial DNA catabolism|mtDNA catabolic process|mitochondrial DNA degradation|mitochondrial DNA breakdown|mtDNA catabolism|mtDNA degradation|mtDNA breakdown http://purl.obolibrary.org/obo/GO_0032043 GO:0032042 biolink:BiologicalProcess mitochondrial DNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. go-plus.json mitochondrial DNA metabolism|mtDNA metabolism|mtDNA metabolic process http://purl.obolibrary.org/obo/GO_0032042 GO:1900518 biolink:BiologicalProcess regulation of response to pullulan Any process that modulates the frequency, rate or extent of response to pullulan. go-plus.json http://purl.obolibrary.org/obo/GO_1900518 GO:0046682 biolink:BiologicalProcess response to cyclodiene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring. go-plus.json cyclodiene susceptibility/resistance|cyclodiene resistance http://purl.obolibrary.org/obo/GO_0046682 GO:1900517 biolink:BiologicalProcess positive regulation of xylose catabolic process to ethanol Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol. go-plus.json positive regulation of xylose catabolism to ethanol|upregulation of xylose catabolic process to ethanol|up regulation of xylose catabolism to ethanol|up regulation of xylose catabolic process to ethanol|upregulation of xylose catabolism to ethanol|activation of xylose catabolic process to ethanol|up-regulation of xylose catabolism to ethanol|up-regulation of xylose catabolic process to ethanol|activation of xylose catabolism to ethanol http://purl.obolibrary.org/obo/GO_1900517 GO:0046681 biolink:BiologicalProcess response to carbamate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase. go-plus.json carbamate resistance|carbamate susceptibility/resistance http://purl.obolibrary.org/obo/GO_0046681 GO:0046680 biolink:BiologicalProcess response to DDT Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals. go-plus.json DDT susceptibility/resistance|DDT resistance http://purl.obolibrary.org/obo/GO_0046680 GO:1900519 biolink:BiologicalProcess negative regulation of response to pullulan Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan. go-plus.json down regulation of response to pullulan|inhibition of response to pullulan|down-regulation of response to pullulan|downregulation of response to pullulan http://purl.obolibrary.org/obo/GO_1900519 GO:1900514 biolink:BiologicalProcess positive regulation of starch utilization system complex assembly Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly. go-plus.json up regulation of SUS complex assembly|positive regulation of assembly of starch utilization system complex|up regulation of starch utilization system complex assembly|activation of assembly of starch utilization system complex|upregulation of SUS complex assembly|up-regulation of assembly of starch utilization system complex|upregulation of starch utilization system complex assembly|up-regulation of SUS complex assembly|upregulation of assembly of starch utilization system complex|up-regulation of starch utilization system complex assembly|activation of SUS complex assembly|activation of starch utilization system complex assembly|positive regulation of SUS complex assembly|up regulation of assembly of starch utilization system complex http://purl.obolibrary.org/obo/GO_1900514 GO:1900513 biolink:BiologicalProcess negative regulation of starch utilization system complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly. go-plus.json down-regulation of starch utilization system complex assembly|downregulation of SUS complex assembly|negative regulation of assembly of starch utilization system complex|down-regulation of assembly of starch utilization system complex|down regulation of SUS complex assembly|downregulation of starch utilization system complex assembly|down regulation of starch utilization system complex assembly|inhibition of SUS complex assembly|inhibition of starch utilization system complex assembly|inhibition of assembly of starch utilization system complex|down regulation of assembly of starch utilization system complex|negative regulation of SUS complex assembly|down-regulation of SUS complex assembly|downregulation of assembly of starch utilization system complex http://purl.obolibrary.org/obo/GO_1900513 GO:1900516 biolink:BiologicalProcess negative regulation of xylose catabolic process to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol. go-plus.json downregulation of xylose catabolism to ethanol|down regulation of xylose catabolic process to ethanol|downregulation of xylose catabolic process to ethanol|down regulation of xylose catabolism to ethanol|inhibition of xylose catabolism to ethanol|down-regulation of xylose catabolic process to ethanol|inhibition of xylose catabolic process to ethanol|down-regulation of xylose catabolism to ethanol|negative regulation of xylose catabolism to ethanol http://purl.obolibrary.org/obo/GO_1900516 GO:1900515 biolink:BiologicalProcess regulation of xylose catabolic process to ethanol Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol. go-plus.json regulation of xylose catabolism to ethanol http://purl.obolibrary.org/obo/GO_1900515 GO:1900510 biolink:BiologicalProcess negative regulation of pentose catabolic process to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol. go-plus.json down-regulation of pentose catabolic process to ethanol|negative regulation of pentose catabolism to ethanol|down-regulation of pentose catabolism to ethanol|downregulation of pentose catabolic process to ethanol|down regulation of pentose catabolic process to ethanol|inhibition of pentose catabolic process to ethanol|inhibition of pentose catabolism to ethanol|down regulation of pentose catabolism to ethanol|downregulation of pentose catabolism to ethanol http://purl.obolibrary.org/obo/GO_1900510 CL:2000034 biolink:Cell anterior lateral line neuromast hair cell Any neuromast hair cell that is part of a anterior lateral line. go-plus.json http://purl.obolibrary.org/obo/CL_2000034 GO:0046689 biolink:BiologicalProcess response to mercury ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus. go-plus.json response to mercuric ion|response to mercury|mercuric sensitivity/resistance http://purl.obolibrary.org/obo/GO_0046689 CL:2000033 biolink:Cell limb basal cell of epidermis Any basal cell of epidermis that is part of a limb. go-plus.json http://purl.obolibrary.org/obo/CL_2000033 GO:0046688 biolink:BiologicalProcess response to copper ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus. go-plus.json response to copper|copper sensitivity/resistance http://purl.obolibrary.org/obo/GO_0046688 GO:1900512 biolink:BiologicalProcess regulation of starch utilization system complex assembly Any process that modulates the frequency, rate or extent of starch utilization system complex assembly. go-plus.json regulation of SUS complex assembly|regulation of assembly of starch utilization system complex http://purl.obolibrary.org/obo/GO_1900512 UBERON:2000120 biolink:AnatomicalEntity lateral line ganglion Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate a lateral line. go-plus.json lateral line ganglia|LLG http://purl.obolibrary.org/obo/UBERON_2000120 CL:2000036 biolink:Cell anterior lateral line neuromast support cell Any neuromast support cell that is part of a anterior lateral line. go-plus.json http://purl.obolibrary.org/obo/CL_2000036 GO:1900511 biolink:BiologicalProcess positive regulation of pentose catabolic process to ethanol Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol. go-plus.json up regulation of pentose catabolism to ethanol|positive regulation of pentose catabolism to ethanol|activation of pentose catabolism to ethanol|up regulation of pentose catabolic process to ethanol|up-regulation of pentose catabolism to ethanol|upregulation of pentose catabolic process to ethanol|upregulation of pentose catabolism to ethanol|up-regulation of pentose catabolic process to ethanol|activation of pentose catabolic process to ethanol http://purl.obolibrary.org/obo/GO_1900511 CL:2000035 biolink:Cell anterior lateral line neuromast mantle cell Any neuromast mantle cell that is part of a anterior lateral line. go-plus.json http://purl.obolibrary.org/obo/CL_2000035 GO:0046687 biolink:BiologicalProcess response to chromate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus. go-plus.json chromate sensitivity/resistance http://purl.obolibrary.org/obo/GO_0046687 CL:2000030 biolink:Cell hypothalamus cell Any native cell that is part of a hypothalamus. go-plus.json http://purl.obolibrary.org/obo/CL_2000030 GO:0046686 biolink:BiologicalProcess response to cadmium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. go-plus.json response to cadmium|cadmium sensitivity/resistance http://purl.obolibrary.org/obo/GO_0046686 GO:0046685 biolink:BiologicalProcess response to arsenic-containing substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. go-plus.json response to arsenic|arsenate sensitivity/resistance http://purl.obolibrary.org/obo/GO_0046685 GO:0046684 biolink:BiologicalProcess response to pyrethroid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage. go-plus.json pyrethroid susceptibility/resistance|pyrethroid resistance http://purl.obolibrary.org/obo/GO_0046684 CL:2000032 biolink:Cell peripheral nervous system neuron Any neuron that is part of a peripheral nervous system. go-plus.json http://purl.obolibrary.org/obo/CL_2000032 CL:2000031 biolink:Cell lateral line ganglion neuron Any neuron that is part of a lateral line ganglion. go-plus.json http://purl.obolibrary.org/obo/CL_2000031 GO:0046683 biolink:BiologicalProcess response to organophosphorus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors. go-plus.json organophosphorus susceptibility/resistance|organophosphorus resistance http://purl.obolibrary.org/obo/GO_0046683 UBERON:0002360 biolink:AnatomicalEntity meninx Membrane organ that surrounds the brain and the spinal cord. go-plus.json meningeal layer|layer of meninges|meninx primitiva http://purl.obolibrary.org/obo/UBERON_0002360 CHEBI:59740 biolink:ChemicalSubstance nucleophilic reagent go-plus.json http://purl.obolibrary.org/obo/CHEBI_59740 UBERON:0002362 biolink:AnatomicalEntity arachnoid mater A think avascular meningeal layer, between the pia mater and the dural mater. It is separated from the pia mater by the subarachnoid space. go-plus.json arachnoid mater of neuraxis|arachnoidea mater|arachnoid|arachnoid membrane http://purl.obolibrary.org/obo/UBERON_0002362 UBERON:0002361 biolink:AnatomicalEntity pia mater The innermost layer of the leptomeninges, consisting of a delicate membrane closely covering the surface of the brain and spinal cord,and lying under the arachnoid membrane. The pia, unlike the arachnoid, extends into the sulci in gyrencephalic animals. go-plus.json pia mater of neuraxis|pial membrane|pia http://purl.obolibrary.org/obo/UBERON_0002361 CHEBI:35774 biolink:ChemicalSubstance CDP-glycerols go-plus.json http://purl.obolibrary.org/obo/CHEBI_35774 CL:2000038 biolink:Cell posterior lateral line neuromast mantle cell Any neuromast mantle cell that is part of a posterior lateral line. go-plus.json http://purl.obolibrary.org/obo/CL_2000038 CHEBI:35776 biolink:ChemicalSubstance arsenic oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35776 GO:0071649 biolink:BiologicalProcess regulation of chemokine (C-C motif) ligand 5 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. go-plus.json regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|regulation of CCL5 production|regulation of RANTES production http://purl.obolibrary.org/obo/GO_0071649 CL:2000037 biolink:Cell posterior lateral line neuromast hair cell Any neuromast hair cell that is part of a posterior lateral line. go-plus.json http://purl.obolibrary.org/obo/CL_2000037 GO:0071648 biolink:BiologicalProcess positive regulation of macrophage inflammatory protein-1 gamma production Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma. go-plus.json positive regulation of MIP-1g production|positive regulation of chemokine (C-C motif) ligand 9 production|positive regulation of CCL9 production http://purl.obolibrary.org/obo/GO_0071648 CHEBI:35779 biolink:ChemicalSubstance dicarboxylic acid diamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35779 GO:0071647 biolink:BiologicalProcess negative regulation of macrophage inflammatory protein-1 gamma production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma. go-plus.json negative regulation of CCL9 production|negative regulation of MIP-1g production|negative regulation of chemokine (C-C motif) ligand 9 production http://purl.obolibrary.org/obo/GO_0071647 CL:2000039 biolink:Cell posterior lateral line neuromast support cell Any neuromast support cell that is part of a posterior lateral line. go-plus.json http://purl.obolibrary.org/obo/CL_2000039 GO:0071646 biolink:BiologicalProcess regulation of macrophage inflammatory protein-1 gamma production Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma. go-plus.json regulation of chemokine (C-C motif) ligand 9 production|regulation of CCL9 production|regulation of MIP-1g production http://purl.obolibrary.org/obo/GO_0071646 UBERON:0002368 biolink:AnatomicalEntity endocrine gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. go-plus.json glandulae endocrinae|glandula endocrina|ductless gland|ductless gland http://purl.obolibrary.org/obo/UBERON_0002368 UBERON:0002367 biolink:AnatomicalEntity prostate gland The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. go-plus.json prostata|male prostate|prostate http://purl.obolibrary.org/obo/UBERON_0002367 GO:0071645 biolink:BiologicalProcess positive regulation of chemokine (C-C motif) ligand 4 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4. go-plus.json positive regulation of CCL4 production|positive regulation of MIP-1b production|positive regulation of macrophage inflammatory protein production http://purl.obolibrary.org/obo/GO_0071645 GO:0071644 biolink:BiologicalProcess negative regulation of chemokine (C-C motif) ligand 4 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4. go-plus.json negative regulation of macrophage inflammatory protein production|negative regulation of CCL4 production|negative regulation of MIP-1b production http://purl.obolibrary.org/obo/GO_0071644 GO:0071643 biolink:BiologicalProcess regulation of chemokine (C-C motif) ligand 4 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4. go-plus.json regulation of macrophage inflammatory protein production|regulation of CCL4 production|regulation of MIP-1b production http://purl.obolibrary.org/obo/GO_0071643 UBERON:0002369 biolink:AnatomicalEntity adrenal gland Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]. go-plus.json adrenal|glandula suprarenalis|interrenal gland|suprarenal gland|glandula suprarenalis|suprarenal capsule|epinephric gland|adrenal capsule|atrabiliary capsule|glandula adrenalis|epinephros|adrenal medulla cell http://purl.obolibrary.org/obo/UBERON_0002369 UBERON:0002364 biolink:AnatomicalEntity tympanic membrane A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted]. go-plus.json eardrum|ear drum|membranous wall of tympanic cavity|Rivinus' membrane|myrinx|paries membranaceus cavi tympani|lateral wall of tympanic cavity|tympanum http://purl.obolibrary.org/obo/UBERON_0002364 GO:0071642 biolink:BiologicalProcess positive regulation of macrophage inflammatory protein 1 alpha production Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. go-plus.json positive regulation of chemokine (C-C motif) ligand 3 production|positive regulation of CCL3 production|positive regulation of MIP-1a production|positive regulation of macrophage inflammatory protein production http://purl.obolibrary.org/obo/GO_0071642 UBERON:0002363 biolink:AnatomicalEntity dura mater Thick, fibrous meningeal covering surrounding the brain and spinal cord. It is the outermost of the three meningeal coverings. It consists of two layers: the periosteal dura linking the inner surface of the skull and the meningeal dura that lies above the arachnoid dural membrane. The meningeal layer draws away from the periosteal layer and certain locations to form the dural reflections. go-plus.json pachymeninges|dura|dura mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0002363 GO:0071641 biolink:BiologicalProcess negative regulation of macrophage inflammatory protein 1 alpha production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. go-plus.json negative regulation of chemokine (C-C motif) ligand 3 production|negative regulation of macrophage inflammatory protein production|negative regulation of CCL3 production|negative regulation of MIP-1a production http://purl.obolibrary.org/obo/GO_0071641 GO:0071640 biolink:BiologicalProcess regulation of macrophage inflammatory protein 1 alpha production Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. go-plus.json regulation of macrophage inflammatory protein production|regulation of chemokine (C-C motif) ligand 3 production|regulation of CCL3 production|regulation of MIP-1a production http://purl.obolibrary.org/obo/GO_0071640 CHEBI:35771 biolink:ChemicalSubstance glycerophosphoinositol phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35771 UBERON:0002365 biolink:AnatomicalEntity exocrine gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas go-plus.json glandula exocrina|ducted gland http://purl.obolibrary.org/obo/UBERON_0002365 GO:1900529 biolink:BiologicalProcess obsolete regulation of cell shape involved in cellular response to glucose starvation OBSOLETE. Any regulation of cell shape that is involved in cellular response to glucose starvation. go-plus.json regulation of cell shape involved in cellular response to glucose starvation http://purl.obolibrary.org/obo/GO_1900529 GO:0046693 biolink:BiologicalProcess sperm storage The retention of sperm by a female following mating. go-plus.json sequestration of sperm|sperm sequestering|sperm retention|storage of sperm|retention of sperm|sperm sequestration|sequestering of sperm http://purl.obolibrary.org/obo/GO_0046693 GO:1900528 biolink:BiologicalProcess obsolete regulation of cell shape involved in G1 to G0 transition OBSOLETE. Any regulation of cell shape that is involved in G1 to G0 transition. go-plus.json regulation of cell shape involved in establishment of cell quiescence|regulation of cell shape involved in cell cycle quiescence|regulation of cell shape involved in G1 to G0 transition|regulation of cell shape involved in stationary phase|regulation of cell shape involved in G1/G0 transition http://purl.obolibrary.org/obo/GO_1900528 GO:0046692 biolink:BiologicalProcess sperm competition Any process that contributes to the success of sperm fertilization in multiply-mated females. Wikipedia:Sperm_competition go-plus.json http://purl.obolibrary.org/obo/GO_0046692 GO:0046691 biolink:CellularComponent intracellular canaliculus An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates. go-plus.json canalicular membrane http://purl.obolibrary.org/obo/GO_0046691 GO:0046690 biolink:BiologicalProcess response to tellurium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus. go-plus.json tellurium sensitivity/resistance|response to tellurium http://purl.obolibrary.org/obo/GO_0046690 GO:1900525 biolink:BiologicalProcess obsolete positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json positive regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900525 GO:1900524 biolink:BiologicalProcess obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json up-regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|upregulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|up regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|activation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900524 UBERON:0002349 biolink:AnatomicalEntity myocardium the middle layer of the heart, comprised mainly of striated cardiac muscle fibers go-plus.json cardiac muscle|muscle of heart|heart myocardium|heart muscle http://purl.obolibrary.org/obo/UBERON_0002349 GO:1900527 biolink:BiologicalProcess obsolete regulation of nucleus size involved in G1 to G0 transition OBSOLETE. Any regulation of nucleus size that is involved in G1 to G0 transition. go-plus.json regulation of nucleus size involved in cell cycle quiescence|regulation of nuclear size involved in establishment of cell quiescence|regulation of nucleus size involved in stationary phase|regulation of nucleus size involved in G1 to G0 transition|regulation of nuclear size involved in G1 to G0 transition|regulation of nucleus size involved in G1/G0 transition|regulation of nuclear volume involved in stationary phase|regulation of nuclear volume involved in G1 to G0 transition|regulation of nuclear volume involved in G1/G0 transition|regulation of nuclear size involved in stationary phase|regulation of nuclear size involved in G1/G0 transition|regulation of nucleus size involved in establishment of cell quiescence|regulation of nuclear size involved in cell cycle quiescence|regulation of nuclear volume involved in establishment of cell quiescence|regulation of nuclear volume involved in cell cycle quiescence http://purl.obolibrary.org/obo/GO_1900527 CHEBI:59739 biolink:ChemicalSubstance electrophilic reagent go-plus.json http://purl.obolibrary.org/obo/CHEBI_59739 GO:1900526 biolink:BiologicalProcess obsolete negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. go-plus.json negative regulation of phosphatidylserine synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine anabolism by negative regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900526 GO:1900521 biolink:BiologicalProcess regulation of response to amylopectin Any process that modulates the frequency, rate or extent of response to amylopectin. go-plus.json http://purl.obolibrary.org/obo/GO_1900521 PR:000021385 biolink:Protein secretin proteolytic cleavage product A secretin that has been processed by proteolytic cleavage. go-plus.json SCT/ClvPrd http://purl.obolibrary.org/obo/PR_000021385 GO:1900520 biolink:BiologicalProcess positive regulation of response to pullulan Any process that activates or increases the frequency, rate or extent of response to pullulan. go-plus.json up regulation of response to pullulan|upregulation of response to pullulan|activation of response to pullulan|up-regulation of response to pullulan http://purl.obolibrary.org/obo/GO_1900520 CL:2000022 biolink:Cell cardiac septum cell Any native cell that is part of a cardiac septum. go-plus.json http://purl.obolibrary.org/obo/CL_2000022 GO:1900523 biolink:BiologicalProcess positive regulation of response to amylopectin Any process that activates or increases the frequency, rate or extent of response to amylopectin. go-plus.json upregulation of response to amylopectin|up regulation of response to amylopectin|activation of response to amylopectin|up-regulation of response to amylopectin http://purl.obolibrary.org/obo/GO_1900523 GO:0046699 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046699 CL:2000025 biolink:Cell spinal cord oligodendrocyte Any oligodendrocyte that is part of a spinal cord. go-plus.json http://purl.obolibrary.org/obo/CL_2000025 GO:0046698 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046698 GO:1900522 biolink:BiologicalProcess negative regulation of response to amylopectin Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin. go-plus.json down regulation of response to amylopectin|downregulation of response to amylopectin|down-regulation of response to amylopectin|inhibition of response to amylopectin http://purl.obolibrary.org/obo/GO_1900522 GO:0046697 biolink:BiologicalProcess decidualization The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta. Wikipedia:Decidualization go-plus.json decidual cell reaction http://purl.obolibrary.org/obo/GO_0046697 GO:0046696 biolink:CellularComponent lipopolysaccharide receptor complex A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens. go-plus.json LPS receptor complex http://purl.obolibrary.org/obo/GO_0046696 CL:2000021 biolink:Cell sebaceous gland cell Any native cell that is part of a sebaceous gland. go-plus.json http://purl.obolibrary.org/obo/CL_2000021 GO:0046695 biolink:CellularComponent SLIK (SAGA-like) complex A SAGA-type histone acetyltransferase complex that contains a smaller form of Spt7 (lacking the SPT8 binding region) than the fungal SAGA complex, and consequently lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction. go-plus.json SLIK/SALSA complex|SAGA (alt) complex|SALSA complex http://purl.obolibrary.org/obo/GO_0046695 CL:2000020 biolink:Cell inner cell mass cell Any native cell that is part of a inner cell mass. go-plus.json http://purl.obolibrary.org/obo/CL_2000020 GO:0046694 biolink:BiologicalProcess sperm incapacitation The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males. go-plus.json http://purl.obolibrary.org/obo/GO_0046694 CHEBI:35783 biolink:ChemicalSubstance bornane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35783 chebi_ph7_3 UBERON:0002351 biolink:AnatomicalEntity sinoatrial node The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]. go-plus.json node of Keith-Flack|Koch's node|cardiac pacemaker|sinus node|sinus node of Keith and Flack|sinu-atrial node|nodus sinuatrialis|sinoatrial node|nodus sinuatrialis|SA node|sinuatrial nodal muscle tissue|sinuatrial node|SA nodal muscle tissue http://purl.obolibrary.org/obo/UBERON_0002351 CHEBI:35786 biolink:ChemicalSubstance phosphosphingolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35786 UBERON:0002350 biolink:AnatomicalEntity conducting system of heart The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO] go-plus.json cardiac conducting system|impulse conducting system|cardiac conduction system|cardiac impulse conducting system|cardionector|central conduction system|heart conduction system|complexus stimulans cordis|systema conducente cordis http://purl.obolibrary.org/obo/UBERON_0002350 CHEBI:35785 biolink:ChemicalSubstance sphingoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35785 GO:0071639 biolink:BiologicalProcess positive regulation of monocyte chemotactic protein-1 production Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1. go-plus.json positive regulation of CCL2 production|positive regulation of MCP-1 production http://purl.obolibrary.org/obo/GO_0071639 CHEBI:35788 biolink:ChemicalSubstance seco-steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35788 GO:0071638 biolink:BiologicalProcess negative regulation of monocyte chemotactic protein-1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1. go-plus.json negative regulation of MCP-1 production|negative regulation of CCL2 production http://purl.obolibrary.org/obo/GO_0071638 GO:0071637 biolink:BiologicalProcess regulation of monocyte chemotactic protein-1 production Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1. go-plus.json regulation of CCL2 production|regulation of MCP-1 production http://purl.obolibrary.org/obo/GO_0071637 CL:2000029 biolink:Cell central nervous system neuron Any neuron that is part of a central nervous system. go-plus.json http://purl.obolibrary.org/obo/CL_2000029 GO:0071636 biolink:BiologicalProcess positive regulation of transforming growth factor beta production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta. go-plus.json positive regulation of TGFbeta production|positive regulation of TGF-beta production|positive regulation of TGFB production|positive regulation of TGF-B production|positive regulation of transforming growth factor-beta production|positive regulation of transforming growth factor-beta secretion http://purl.obolibrary.org/obo/GO_0071636 CHEBI:35789 biolink:ChemicalSubstance oxo steroid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35789 CL:2000028 biolink:Cell cerebellum glutamatergic neuron Any glutamatergic neuron that is part of a cerebellum. go-plus.json http://purl.obolibrary.org/obo/CL_2000028 UBERON:0002357 biolink:AnatomicalEntity serous pericardium Serous membrane which is divided into parietal and visceral serous pericardium. go-plus.json serous portion of pericardium|pericardium serosum http://purl.obolibrary.org/obo/UBERON_0002357 GO:0071635 biolink:BiologicalProcess negative regulation of transforming growth factor beta production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta. go-plus.json negative regulation of TGFbeta production|negative regulation of TGF-beta production|negative regulation of TGF-B production|negative regulation of TGFB production|negative regulation of transforming growth factor-beta production|negative regulation of transforming growth factor-beta secretion http://purl.obolibrary.org/obo/GO_0071635 CHEBI:59737 biolink:ChemicalSubstance nucleotide-sugar oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59737 GO:0071634 biolink:BiologicalProcess regulation of transforming growth factor beta production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta. go-plus.json regulation of transforming growth factor-beta production|regulation of TGF-beta production|regulation of TGFB production|regulation of TGFbeta production|regulation of transforming growth factor-beta secretion|regulation of TGF-B production http://purl.obolibrary.org/obo/GO_0071634 UBERON:0002359 biolink:AnatomicalEntity fibrous pericardium Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA] go-plus.json pericardium fibrosum|fibrous portion of pericardium http://purl.obolibrary.org/obo/UBERON_0002359 GO:0071633 biolink:MolecularActivity dihydroceramidase activity Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine. go-plus.json http://purl.obolibrary.org/obo/GO_0071633 UBERON:0002358 biolink:AnatomicalEntity peritoneum A serous membrane that lines the peritoneal cavity[VHOG,modified]. go-plus.json peritonaeum http://purl.obolibrary.org/obo/UBERON_0002358 GO:0071632 biolink:BiologicalProcess optomotor response Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish. Wikipedia:Optomotor_response go-plus.json http://purl.obolibrary.org/obo/GO_0071632 UBERON:0002353 biolink:AnatomicalEntity bundle of His A part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers[GO] go-plus.json AV bundle|AVB|atrio-ventricular bundle|fasciculus atrioventricularis|atrioventricular bundle|bundle of His|atrioventricular fasciculus|atrioventricular bundle muscle tissue|A-V bundle|His bundle http://purl.obolibrary.org/obo/UBERON_0002353 GO:0071631 biolink:BiologicalProcess mating pheromone secretion involved in positive regulation of conjugation with cellular fusion The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types. go-plus.json mating-type pheromone secretion involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0071631 CHEBI:11791 biolink:ChemicalSubstance 3-deoxy-D-manno-octulosonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_11791 CHEBI:35780 biolink:ChemicalSubstance phosphate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35780 GO:0071630 biolink:BiologicalProcess nuclear protein quality control by the ubiquitin-proteasome system The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation. go-plus.json nucleus-associated proteasomal ubiquitin-dependent protein breakdown|nucleus-associated proteasomal ubiquitin-dependent protein catabolism|nucleus-associated proteasomal ubiquitin-dependent protein degradation|ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome http://purl.obolibrary.org/obo/GO_0071630 UBERON:0002352 biolink:AnatomicalEntity atrioventricular node An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles. go-plus.json downstream pacemaker|AV node|atriovetricular node|Aschoff-Tawara node|atrio-ventricular node|nodus atrioventricularis|nodus atrioventricularis|atrioventricular nodal muscle tissue|AV nodal muscle tissue|A-V node|node of Tawara http://purl.obolibrary.org/obo/UBERON_0002352 CHEBI:35782 biolink:ChemicalSubstance diphosphate ion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35782 UBERON:0002355 biolink:AnatomicalEntity pelvic region of trunk The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs. go-plus.json pelvis region|pelvis|lesser pelvis|true pelvis|pelvic region http://purl.obolibrary.org/obo/UBERON_0002355 UBERON:0002354 biolink:AnatomicalEntity cardiac Purkinje fiber The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle go-plus.json cardiac Purkinje fiber|Purkinje fiber|heart Purkinje fiber|myofibra conducens cardiacus|subendocardial branch http://purl.obolibrary.org/obo/UBERON_0002354 GO:0071660 biolink:BiologicalProcess positive regulation of IP-10 production Any process that activates or increases the frequency, rate, or extent of production of IP-10. go-plus.json positive regulation of CXCL10 production|positive regulation of chemokine (C-C motif) ligand 10 production http://purl.obolibrary.org/obo/GO_0071660 GO:1900539 biolink:BiologicalProcess fumonisin metabolic process The chemical reactions and pathways involving fumonisin. go-plus.json fumonisin metabolism http://purl.obolibrary.org/obo/GO_1900539 UBERON:0002339 biolink:AnatomicalEntity epithelium of lobar bronchus The tissue made up of epithelial cells that lines the inside of the lobar bronchus. go-plus.json epithelial tissue of lobar bronchus|epithelial tissue of secondary bronchus|epithelium of secondary bronchus|lobar bronchus epithelial tissue|secondary bronchus epithelium|secondary bronchus epithelial tissue|lobar bronchus epithelium|lobar bronchial epithelium http://purl.obolibrary.org/obo/UBERON_0002339 GO:1900536 biolink:BiologicalProcess obsolete regulation of glucose homeostasis OBSOLETE. Any process that modulates the frequency, rate or extent of glucose homeostasis. go-plus.json regulation of glucose homeostasis http://purl.obolibrary.org/obo/GO_1900536 UBERON:0002338 biolink:AnatomicalEntity lamina propria of bronchus A lamina propria that is part of a bronchus [Automatically generated definition]. go-plus.json lamina propria mucosa of bronchi|lamina propria mucosa of bronchial trunk|lamina propria mucosa of bronchus|bronchi lamina propria mucosa|bronchial trunk lamina propria mucosa|bronchus lamina propria mucosa|lamina propria mucosae of bronchus|bronchial lamina propria|lamina propria of bronchi|lamina propria of bronchial trunk|lamina propria mucosae of bronchi|lamina propria mucosae of bronchial trunk|bronchus lamina propria mucosae|bronchial trunk lamina propria mucosae|bronchi lamina propria mucosae|bronchus lamina propria|bronchial trunk lamina propria|bronchi lamina propria http://purl.obolibrary.org/obo/UBERON_0002338 GO:1900535 biolink:BiologicalProcess palmitic acid biosynthetic process The chemical reactions and pathways resulting in the formation of palmitic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1900535 GO:1900538 biolink:BiologicalProcess obsolete positive regulation of glucose homeostasis OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose homeostasis. go-plus.json up-regulation of glucose homeostasis|positive regulation of glucose homeostasis|upregulation of glucose homeostasis|up regulation of glucose homeostasis|activation of glucose homeostasis http://purl.obolibrary.org/obo/GO_1900538 GO:1900537 biolink:BiologicalProcess obsolete negative regulation of glucose homeostasis OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose homeostasis. go-plus.json inhibition of glucose homeostasis|negative regulation of glucose homeostasis|down regulation of glucose homeostasis|downregulation of glucose homeostasis|down-regulation of glucose homeostasis http://purl.obolibrary.org/obo/GO_1900537 CHEBI:35759 biolink:ChemicalSubstance 1-monoglyceride go-plus.json http://purl.obolibrary.org/obo/CHEBI_35759 chebi_ph7_3 GO:1900532 biolink:BiologicalProcess obsolete negative regulation of cell proliferation involved in cellular hyperosmotic response OBSOLETE. Negative regulation of cell proliferation during cellular hyperosmotic response. go-plus.json down regulation of cell proliferation of cellular response to hypertonicity|inhibition of cell proliferation of cellular response to hypertonicity|down regulation of cell proliferation of cellular hyperosmotic response|inhibition of cell proliferation of cellular hyperosmotic response|downregulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation involved in cellular hyperosmotic response|down regulation of cell proliferation of cellular hypertonic response|inhibition of cell proliferation of cellular hypertonic response|down regulation of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular HOG response|negative regulation of cell proliferation of cellular response to hypertonicity|down-regulation of cell proliferation of cellular response to hypertonicity|negative regulation of cell proliferation of cellular hyperosmotic response|down-regulation of cell proliferation of cellular hyperosmotic response|negative regulation of cell proliferation of cellular HOG response|down-regulation of cell proliferation of cellular HOG response|down-regulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation of cellular hypertonic response|downregulation of cell proliferation of cellular response to hypertonicity|inhibition of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular hyperosmotic response http://purl.obolibrary.org/obo/GO_1900532 CL:2000056 biolink:Cell Meynert cell Any pyramidal cell that is part of a regional part of cerebral cortex. go-plus.json http://purl.obolibrary.org/obo/CL_2000056 GO:1900531 biolink:BiologicalProcess obsolete regulation of cell shape involved in cellular response to heat OBSOLETE. Any regulation of cell shape that is involved in cellular response to heat. go-plus.json regulation of cell shape involved in cellular response to heat|regulation of cell shape of cellular response to heat|regulation of cell shape of cellular response to heat stress http://purl.obolibrary.org/obo/GO_1900531 CL:2000055 biolink:Cell liver dendritic cell Any dendritic cell that is part of a liver. go-plus.json hepatic dendritic cell http://purl.obolibrary.org/obo/CL_2000055 GO:1900534 biolink:BiologicalProcess palmitic acid catabolic process The chemical reactions and pathways resulting in the breakdown of palmitic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1900534 GO:1900533 biolink:BiologicalProcess palmitic acid metabolic process The chemical reactions and pathways involving palmitic acid. go-plus.json http://purl.obolibrary.org/obo/GO_1900533 CL:2000052 biolink:Cell umbilical artery endothelial cell Any endothelial cell of artery that is part of a umbilical cord. go-plus.json http://purl.obolibrary.org/obo/CL_2000052 CL:2000051 biolink:Cell splenic fibroblast Any fibroblast that is part of a spleen. go-plus.json http://purl.obolibrary.org/obo/CL_2000051 GO:1900530 biolink:BiologicalProcess obsolete regulation of cell shape involved in cellular response to salt stress OBSOLETE. Any regulation of cell shape that is involved in cellular response to salt stress. go-plus.json regulation of cell shape of cellular response to ionic osmotic stress|regulation of cell shape of cellular response to salt stress|regulation of cell shape of cellular salinity response|regulation of cell shape involved in cellular response to salt stress http://purl.obolibrary.org/obo/GO_1900530 CL:2000053 biolink:Cell splenic endothelial cell Any endothelial cell that is part of a spleen. go-plus.json http://purl.obolibrary.org/obo/CL_2000053 CHEBI:35753 biolink:ChemicalSubstance tricarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35753 CHEBI:35755 biolink:ChemicalSubstance pentacarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35755 CHEBI:35754 biolink:ChemicalSubstance tetracarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35754 CHEBI:35757 biolink:ChemicalSubstance monocarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35757 chebi_ph7_3 GO:0071669 biolink:BiologicalProcess plant-type cell wall organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall. go-plus.json plant-type cell wall organization and biogenesis|plant-type cell wall organisation or biogenesis http://purl.obolibrary.org/obo/GO_0071669 UBERON:0002346 biolink:AnatomicalEntity neurectoderm Embryonic ectoderm that gives rise to nervous tissue. go-plus.json epithelium tubi neuralis; neuroectoderma|presumptive central nervous system|neuaral ectoderm|neural ectoderm|neuroectoderm|ventral neurogenic region http://purl.obolibrary.org/obo/UBERON_0002346 GO:0071668 biolink:BiologicalProcess plant-type cell wall assembly The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall. go-plus.json plant cell wall assembly http://purl.obolibrary.org/obo/GO_0071668 GO:0071667 biolink:MolecularActivity DNA/RNA hybrid binding Binding to a RNA/DNA hybrid. go-plus.json RNA/DNA hybrid binding http://purl.obolibrary.org/obo/GO_0071667 UBERON:0002348 biolink:AnatomicalEntity epicardium a region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. go-plus.json pericardium visceral mesothelium|visceral serous pericardium proper|heart epicardium|visceral serous pericardium of heart http://purl.obolibrary.org/obo/UBERON_0002348 GO:0071666 biolink:CellularComponent Slit-Robo signaling complex A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate. go-plus.json Slit-Robo signalling complex http://purl.obolibrary.org/obo/GO_0071666 CHEBI:59724 biolink:ChemicalSubstance ribonucleoside triphosphate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59724 GO:0071665 biolink:CellularComponent gamma-catenin-TCF7L2 complex A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. go-plus.json plakoglobin-TCF4 complex|gamma-catenin-TCF4 complex http://purl.obolibrary.org/obo/GO_0071665 UBERON:0002347 biolink:AnatomicalEntity thoracic vertebra A thoracic vertebra endochondral element that is composed primarily of a bone tissue. go-plus.json vertebra of thorax|thorax vertebra|vertebra thoracica|dorsal vertebra http://purl.obolibrary.org/obo/UBERON_0002347 GO:0071664 biolink:CellularComponent catenin-TCF7L2 complex A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. go-plus.json catenin-TCF4 complex http://purl.obolibrary.org/obo/GO_0071664 UBERON:0002342 biolink:AnatomicalEntity neural crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. go-plus.json crista neuralis|NC|neural crest material http://purl.obolibrary.org/obo/UBERON_0002342 UBERON:0002341 biolink:AnatomicalEntity epithelium of segmental bronchus An epithelium that is part of a segmental bronchus [Automatically generated definition]. go-plus.json segmental bronchus epithelial tissue|segmental bronchus epithelium|epithelium of tertiary bronchus|epithelial tissue of tertiary bronchus|segmental bronchial epithelium|tertiary bronchus epithelial tissue|tertiary bronchus epithelium|epithelial tissue of segmental bronchus http://purl.obolibrary.org/obo/UBERON_0002341 GO:0071663 biolink:BiologicalProcess positive regulation of granzyme B production Any process that activates or increases the frequency, rate, or extent of production of granzyme B. go-plus.json http://purl.obolibrary.org/obo/GO_0071663 GO:0071662 biolink:BiologicalProcess negative regulation of granzyme B production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B. go-plus.json http://purl.obolibrary.org/obo/GO_0071662 CHEBI:59720 biolink:ChemicalSubstance HPETE anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59720 chebi_ph7_3 GO:0071661 biolink:BiologicalProcess regulation of granzyme B production Any process that modulates the frequency, rate, or extent of production of granzyme B. go-plus.json http://purl.obolibrary.org/obo/GO_0071661 UBERON:0002343 biolink:AnatomicalEntity abdomen musculature Set of all muscles in abdomen. go-plus.json muscles of abdomen|musculature of abdomen|abdominal musculature|muscle group of abdomen|set of muscles of abdomen|musculature of abdominal wall http://purl.obolibrary.org/obo/UBERON_0002343 UBERON:0002328 biolink:AnatomicalEntity notochord A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. go-plus.json embryonic notocord|notochorda|notocord http://purl.obolibrary.org/obo/UBERON_0002328 GO:1900547 biolink:BiologicalProcess obsolete negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching. go-plus.json negative regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900547 GO:1900546 biolink:BiologicalProcess obsolete positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching. go-plus.json up regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|activation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|activation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|positive regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900546 UBERON:0002327 biolink:AnatomicalEntity trunk of intercostal nerve go-plus.json intercostal neural trunk|intercostal nerve trunk http://purl.obolibrary.org/obo/UBERON_0002327 GO:1900549 biolink:BiologicalProcess N',N'',N'''-triacetylfusarinine C metabolic process The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C. go-plus.json N',N'',N'''-triacetylfusarinine C metabolism http://purl.obolibrary.org/obo/GO_1900549 GO:1900548 biolink:BiologicalProcess heme B catabolic process The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. MetaCyc:PWY-5874 go-plus.json protoheme catabolic process|heme B degradation|heme B breakdown|heme B catabolism|protoheme degradation http://purl.obolibrary.org/obo/GO_1900548 UBERON:0002329 biolink:AnatomicalEntity somite Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. go-plus.json somites|epimere|epimere mesoderm|somitus|somitic mesoderm|mesodermal cluster|epithelial somite http://purl.obolibrary.org/obo/UBERON_0002329 GO:1900543 biolink:BiologicalProcess negative regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process. go-plus.json downregulation of purine metabolism|inhibition of purine metabolic process|down-regulation of purine nucleotide metabolic process|downregulation of purine nucleotide metabolism|negative regulation of purine metabolism|down regulation of purine nucleotide metabolism|down-regulation of purine metabolism|inhibition of purine nucleotide metabolism|inhibition of purine nucleotide metabolic process|negative regulation of purine metabolic process|down-regulation of purine metabolic process|inhibition of purine metabolism|downregulation of purine metabolic process|down regulation of purine nucleotide metabolic process|down regulation of purine metabolic process|downregulation of purine nucleotide metabolic process|negative regulation of purine nucleotide metabolism|down-regulation of purine nucleotide metabolism|down regulation of purine metabolism http://purl.obolibrary.org/obo/GO_1900543 GO:1900542 biolink:BiologicalProcess regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process. go-plus.json regulation of purine nucleotide metabolism|regulation of purine metabolic process|regulation of purine metabolism http://purl.obolibrary.org/obo/GO_1900542 GO:1900545 biolink:BiologicalProcess obsolete regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of phenotypic switching. go-plus.json regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter http://purl.obolibrary.org/obo/GO_1900545 CL:2000047 biolink:Cell brainstem motor neuron Any motor neuron that is part of a brainstem. go-plus.json http://purl.obolibrary.org/obo/CL_2000047 GO:1900544 biolink:BiologicalProcess positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process. go-plus.json up regulation of purine nucleotide metabolic process|activation of purine nucleotide metabolic process|positive regulation of purine nucleotide metabolism|up regulation of purine nucleotide metabolism|up regulation of purine metabolism|positive regulation of purine metabolism|up-regulation of purine metabolic process|activation of purine metabolism|up-regulation of purine nucleotide metabolic process|activation of purine metabolic process|upregulation of purine nucleotide metabolism|up-regulation of purine metabolism|positive regulation of purine metabolic process|up regulation of purine metabolic process|upregulation of purine nucleotide metabolic process|activation of purine nucleotide metabolism|up-regulation of purine nucleotide metabolism|upregulation of purine metabolism|upregulation of purine metabolic process http://purl.obolibrary.org/obo/GO_1900544 CL:2000046 biolink:Cell ventricular cardiac muscle cell Any cardiac muscle cell that is part of a cardiac ventricle. go-plus.json http://purl.obolibrary.org/obo/CL_2000046 GO:1900541 biolink:BiologicalProcess fumonisin biosynthetic process The chemical reactions and pathways resulting in the formation of fumonisin. go-plus.json fumonisin anabolism|fumonisin biosynthesis|fumonisin synthesis|fumonisin formation http://purl.obolibrary.org/obo/GO_1900541 CL:2000043 biolink:Cell brain pericyte Any pericyte cell that is part of a brain. go-plus.json http://purl.obolibrary.org/obo/CL_2000043 GO:1900540 biolink:BiologicalProcess fumonisin catabolic process The chemical reactions and pathways resulting in the breakdown of fumonisin. go-plus.json fumonisin breakdown|fumonisin degradation|fumonisin catabolism http://purl.obolibrary.org/obo/GO_1900540 CL:2000042 biolink:Cell embryonic fibroblast Any fibroblast that is part of a embryo. go-plus.json http://purl.obolibrary.org/obo/CL_2000042 CL:2000049 biolink:Cell primary motor cortex pyramidal cell Any pyramidal cell that is part of a primary motor cortex. go-plus.json http://purl.obolibrary.org/obo/CL_2000049 CHEBI:35766 biolink:ChemicalSubstance glycerophosphoserine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35766 GO:0071659 biolink:BiologicalProcess negative regulation of IP-10 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10. go-plus.json negative regulation of CXCL10 production|negative regulation of chemokine (C-C motif) ligand 10 production http://purl.obolibrary.org/obo/GO_0071659 GO:0071658 biolink:BiologicalProcess regulation of IP-10 production Any process that modulates the frequency, rate, or extent of production of IP-10. go-plus.json regulation of chemokine (C-C motif) ligand 10 production|regulation of CXCL10 production http://purl.obolibrary.org/obo/GO_0071658 GO:0071657 biolink:BiologicalProcess positive regulation of granulocyte colony-stimulating factor production Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor. go-plus.json positive regulation of colony stimulating factor 3 (granulocyte) production|positive regulation of lenograstim production|positive regulation of pluripoietin production|positive regulation of granulocyte colony stimulating factor production|positive regulation of filgrastim production|positive regulation of G-CSF production|positive regulation of CSF3 production http://purl.obolibrary.org/obo/GO_0071657 UBERON:0002335 biolink:AnatomicalEntity macula densa The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002335 GO:0071656 biolink:BiologicalProcess negative regulation of granulocyte colony-stimulating factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor. go-plus.json negative regulation of CSF3 production|negative regulation of colony stimulating factor 3 (granulocyte) production|negative regulation of lenograstim production|negative regulation of granulocyte colony stimulating factor production|negative regulation of pluripoietin production|negative regulation of filgrastim production|negative regulation of G-CSF production http://purl.obolibrary.org/obo/GO_0071656 UBERON:0002334 biolink:AnatomicalEntity submandibular duct the duct of the submadibular gland that opens at the sublingual papilla near the frenulum of the tongue go-plus.json ductus submandibularis|submandibular salivary duct|Wharton's duct|ductus submaxillaris|submaxillary duct|submaxillar gland duct http://purl.obolibrary.org/obo/UBERON_0002334 CHEBI:176497 biolink:ChemicalSubstance geroprotector go-plus.json http://purl.obolibrary.org/obo/CHEBI_176497 GO:0071655 biolink:BiologicalProcess regulation of granulocyte colony-stimulating factor production Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor. go-plus.json regulation of G-CSF production|regulation of pluripoietin production|regulation of filgrastim production|regulation of colony stimulating factor 3 (granulocyte) production|regulation of lenograstim production|regulation of CSF3 production|regulation of granulocyte colony stimulating factor production http://purl.obolibrary.org/obo/GO_0071655 UBERON:0002337 biolink:AnatomicalEntity endometrial stroma The layer of connective tissue comprised of the endometrial lining of the uterus which fluctuates in thickness throughout the menstrual cycle. go-plus.json stroma of endometrium|endometrium stroma http://purl.obolibrary.org/obo/UBERON_0002337 GO:0071654 biolink:BiologicalProcess positive regulation of chemokine (C-C motif) ligand 1 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1. go-plus.json positive regulation of TCA-3 production|positive regulation of CCL1 production|positive regulation of T cell activation 3 production http://purl.obolibrary.org/obo/GO_0071654 UBERON:0002336 biolink:AnatomicalEntity corpus callosum White matter structure containing massive numbers of commissural fibers connecting cortical areas in the two cerebral hemispheres.it is subdivided into a genu, a rostrum, a body, and a splenium. (MM) go-plus.json http://purl.obolibrary.org/obo/UBERON_0002336 UBERON:0002331 biolink:AnatomicalEntity umbilical cord The connecting cord from the developing embryo to the placenta. go-plus.json connecting stalk|yolk stalk|funiculus umbilicalis|funiculus umbilicalis|chorda umbilicalis|birth cord http://purl.obolibrary.org/obo/UBERON_0002331 GO:0071653 biolink:BiologicalProcess negative regulation of chemokine (C-C motif) ligand 1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1. go-plus.json negative regulation of T cell activation 3 production|negative regulation of CCL1 production|negative regulation of TCA-3 production http://purl.obolibrary.org/obo/GO_0071653 GO:0071652 biolink:BiologicalProcess regulation of chemokine (C-C motif) ligand 1 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1. go-plus.json regulation of TCA-3 production|regulation of T cell activation 3 production|regulation of CCL1 production http://purl.obolibrary.org/obo/GO_0071652 UBERON:0002330 biolink:AnatomicalEntity exocrine system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. go-plus.json exocrine glandular system http://purl.obolibrary.org/obo/UBERON_0002330 GO:0071651 biolink:BiologicalProcess positive regulation of chemokine (C-C motif) ligand 5 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. go-plus.json positive regulation of CCL5 production|positive regulation of RANTES production|positive regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production http://purl.obolibrary.org/obo/GO_0071651 UBERON:0002333 biolink:AnatomicalEntity pulmonary trunk An arterial trunk which is continuous with the heart and branches into the pulmonary arteries. go-plus.json main pulmonary artery|pulmonary artery (trunk)|trunk of pulmonary arterial tree http://purl.obolibrary.org/obo/UBERON_0002333 GO:0071650 biolink:BiologicalProcess negative regulation of chemokine (C-C motif) ligand 5 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. go-plus.json negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|negative regulation of CCL5 production|negative regulation of RANTES production http://purl.obolibrary.org/obo/GO_0071650 GO:0071682 biolink:CellularComponent endocytic vesicle lumen The volume enclosed by the membrane of an endocytic vesicle. go-plus.json http://purl.obolibrary.org/obo/GO_0071682 GO:0071681 biolink:BiologicalProcess cellular response to indole-3-methanol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. go-plus.json cellular response to indole-3-carbinol http://purl.obolibrary.org/obo/GO_0071681 GO:0071680 biolink:BiologicalProcess response to indole-3-methanol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. go-plus.json response to indole-3-carbinol http://purl.obolibrary.org/obo/GO_0071680 GO:1900558 biolink:BiologicalProcess austinol metabolic process The chemical reactions and pathways involving austinol. go-plus.json austinol metabolism http://purl.obolibrary.org/obo/GO_1900558 GO:1900557 biolink:BiologicalProcess emericellamide biosynthetic process The chemical reactions and pathways resulting in the formation of emericellamide. go-plus.json emericellamide biosynthesis|emericellamide anabolism|emericellamide synthesis|emericellamide formation http://purl.obolibrary.org/obo/GO_1900557 GO:1900559 biolink:BiologicalProcess austinol catabolic process The chemical reactions and pathways resulting in the breakdown of austinol. go-plus.json austinol breakdown|austinol catabolism|austinol degradation http://purl.obolibrary.org/obo/GO_1900559 CHEBI:35737 biolink:ChemicalSubstance monothiocarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35737 GO:1900554 biolink:BiologicalProcess asperfuranone biosynthetic process The chemical reactions and pathways resulting in the formation of asperfuranone. go-plus.json asperfuranone synthesis|asperfuranone formation|asperfuranone biosynthesis|asperfuranone anabolism http://purl.obolibrary.org/obo/GO_1900554 GO:1900553 biolink:BiologicalProcess asperfuranone catabolic process The chemical reactions and pathways resulting in the breakdown of asperfuranone. go-plus.json asperfuranone catabolism|asperfuranone degradation|asperfuranone breakdown http://purl.obolibrary.org/obo/GO_1900553 GO:1900556 biolink:BiologicalProcess emericellamide catabolic process The chemical reactions and pathways resulting in the breakdown of emericellamide. go-plus.json emericellamide degradation|emericellamide breakdown|emericellamide catabolism http://purl.obolibrary.org/obo/GO_1900556 GO:1900555 biolink:BiologicalProcess emericellamide metabolic process The chemical reactions and pathways involving emericellamide. go-plus.json emericellamide metabolism http://purl.obolibrary.org/obo/GO_1900555 GO:1900550 biolink:BiologicalProcess N',N'',N'''-triacetylfusarinine C catabolic process The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C. go-plus.json N',N'',N'''-triacetylfusarinine C degradation|N',N'',N'''-triacetylfusarinine C catabolism|N',N'',N'''-triacetylfusarinine C breakdown http://purl.obolibrary.org/obo/GO_1900550 GO:1900552 biolink:BiologicalProcess asperfuranone metabolic process The chemical reactions and pathways involving asperfuranone. go-plus.json asperfuranone metabolism http://purl.obolibrary.org/obo/GO_1900552 GO:1900551 biolink:BiologicalProcess N',N'',N'''-triacetylfusarinine C biosynthetic process The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C. go-plus.json N',N'',N'''-triacetylfusarinine C anabolism|N',N'',N'''-triacetylfusarinine C synthesis|N',N'',N'''-triacetylfusarinine C formation|N',N'',N'''-triacetylfusarinine C biosynthesis http://purl.obolibrary.org/obo/GO_1900551 CHEBI:35735 biolink:ChemicalSubstance dicarboxylic acid monoamide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35735 GO:0071689 biolink:BiologicalProcess muscle thin filament assembly The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0071689 GO:0071688 biolink:BiologicalProcess striated muscle myosin thick filament assembly The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0071688 GO:0071687 biolink:CellularComponent obsolete horsetail nucleus leading edge OBSOLETE. The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe. go-plus.json http://purl.obolibrary.org/obo/GO_0071687 GO:0071686 biolink:CellularComponent obsolete horsetail nucleus OBSOLETE. The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe. go-plus.json http://purl.obolibrary.org/obo/GO_0071686 GO:0071685 biolink:CellularComponent NADH dehydrogenase complex (plastoquinone) An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids. go-plus.json http://purl.obolibrary.org/obo/GO_0071685 GO:0071684 biolink:BiologicalProcess organism emergence from protective structure The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case. go-plus.json http://purl.obolibrary.org/obo/GO_0071684 GO:0071683 biolink:CellularComponent sensory dendrite A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron. go-plus.json http://purl.obolibrary.org/obo/GO_0071683 GO:0071671 biolink:BiologicalProcess regulation of smooth muscle cell chemotaxis Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_0071671 GO:0071670 biolink:BiologicalProcess smooth muscle cell chemotaxis The directed movement of a smooth muscle cell in response to an external stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071670 CHEBI:21101 biolink:ChemicalSubstance D-altraric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21101 CHEBI:21100 biolink:ChemicalSubstance D-altrarate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_21100 GO:1900569 biolink:BiologicalProcess chanoclavine-I aldehyde biosynthetic process The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. go-plus.json chanoclavine-I aldehyde anabolism|chanoclavine-I aldehyde synthesis|chanoclavine-I aldehyde biosynthesis|chanoclavine-I aldehyde formation http://purl.obolibrary.org/obo/GO_1900569 GO:1900568 biolink:BiologicalProcess chanoclavine-I aldehyde catabolic process The chemical reactions and pathways resulting in the breakdown of chanoclavine-I aldehyde. go-plus.json chanoclavine-I aldehyde degradation|chanoclavine-I aldehyde breakdown|chanoclavine-I aldehyde catabolism http://purl.obolibrary.org/obo/GO_1900568 GO:1900565 biolink:BiologicalProcess chanoclavine-I catabolic process The chemical reactions and pathways resulting in the breakdown of chanoclavine-I. go-plus.json chanoclavine-I breakdown|chanoclavine-I catabolism|chanoclavine-I degradation http://purl.obolibrary.org/obo/GO_1900565 CHEBI:35748 biolink:ChemicalSubstance fatty acid ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_35748 chebi_ph7_3 GO:1900564 biolink:BiologicalProcess chanoclavine-I metabolic process The chemical reactions and pathways involving chanoclavine-I. go-plus.json chanoclavine-I metabolism http://purl.obolibrary.org/obo/GO_1900564 GO:1900567 biolink:BiologicalProcess chanoclavine-I aldehyde metabolic process The chemical reactions and pathways involving chanoclavine-I aldehyde. go-plus.json chanoclavine-I aldehyde metabolism http://purl.obolibrary.org/obo/GO_1900567 GO:1900566 biolink:BiologicalProcess chanoclavine-I biosynthetic process The chemical reactions and pathways resulting in the formation of chanoclavine-I. go-plus.json chanoclavine-I anabolism|chanoclavine-I synthesis|chanoclavine-I formation|chanoclavine-I biosynthesis http://purl.obolibrary.org/obo/GO_1900566 GO:1900561 biolink:BiologicalProcess dehydroaustinol metabolic process The chemical reactions and pathways involving dehydroaustinol. go-plus.json dehydroaustinol metabolism http://purl.obolibrary.org/obo/GO_1900561 GO:1900560 biolink:BiologicalProcess austinol biosynthetic process The chemical reactions and pathways resulting in the formation of austinol. go-plus.json austinol biosynthesis|austinol anabolism|austinol synthesis|austinol formation http://purl.obolibrary.org/obo/GO_1900560 GO:1900563 biolink:BiologicalProcess dehydroaustinol biosynthetic process The chemical reactions and pathways resulting in the formation of dehydroaustinol. go-plus.json dehydroaustinol anabolism|dehydroaustinol synthesis|dehydroaustinol formation|dehydroaustinol biosynthesis http://purl.obolibrary.org/obo/GO_1900563 GO:1900562 biolink:BiologicalProcess dehydroaustinol catabolic process The chemical reactions and pathways resulting in the breakdown of dehydroaustinol. go-plus.json dehydroaustinol degradation|dehydroaustinol catabolism|dehydroaustinol breakdown http://purl.obolibrary.org/obo/GO_1900562 CHEBI:35740 biolink:ChemicalSubstance liposaccharide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35740 CHEBI:11750 biolink:ChemicalSubstance 3-sn-phosphatidyl-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_11750 CHEBI:35742 biolink:ChemicalSubstance tetracarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35742 GO:1900570 biolink:BiologicalProcess diorcinol metabolic process The chemical reactions and pathways involving diorcinol. go-plus.json diorcinol metabolism http://purl.obolibrary.org/obo/GO_1900570 UBERON:0002394 biolink:AnatomicalEntity bile duct Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine. go-plus.json gall duct|bile tube|hepatic duct|biliary duct http://purl.obolibrary.org/obo/UBERON_0002394 CHEBI:35741 biolink:ChemicalSubstance glycerolipid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35741 CHEBI:35744 biolink:ChemicalSubstance carbocyclic fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35744 CHEBI:35743 biolink:ChemicalSubstance pentacarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35743 UBERON:0002391 biolink:AnatomicalEntity lymph Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP]. go-plus.json lympha http://purl.obolibrary.org/obo/UBERON_0002391 CHEBI:35746 biolink:ChemicalSubstance fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_35746 chebi_ph7_3 UBERON:0002390 biolink:AnatomicalEntity hematopoietic system Anatomical system that is involved in the production of hematopoietic cells. go-plus.json haematological system|Blutbildungssystem|hemopoietic system|haematopoietic system|hematological system|organa haemopoietica|hematolymphoid system|haemopoietic system http://purl.obolibrary.org/obo/UBERON_0002390 GO:0071679 biolink:BiologicalProcess commissural neuron axon guidance The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues. go-plus.json commissural neuron axon pathfinding http://purl.obolibrary.org/obo/GO_0071679 GO:0071678 biolink:BiologicalProcess olfactory bulb axon guidance The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues. go-plus.json olfactory bulb axon pathfinding http://purl.obolibrary.org/obo/GO_0071678 GO:0071677 biolink:BiologicalProcess positive regulation of mononuclear cell migration Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. go-plus.json stimulation of mononuclear cell migration|up-regulation of mononuclear cell migration|activation of mononuclear cell migration|up regulation of mononuclear cell migration|upregulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071677 GO:0071676 biolink:BiologicalProcess negative regulation of mononuclear cell migration Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. go-plus.json down-regulation of mononuclear cell migration|downregulation of mononuclear cell migration|down regulation of mononuclear cell migration|inhibition of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071676 UBERON:0002397 biolink:AnatomicalEntity maxilla The bone which normally forms the lateral upper jaw in osteichthyans, including tetrapods. go-plus.json maxillae|maxillary bone|upper jaw bone http://purl.obolibrary.org/obo/UBERON_0002397 GO:0071675 biolink:BiologicalProcess regulation of mononuclear cell migration Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0071675 UBERON:0002396 biolink:AnatomicalEntity vomer the triangular flat bone of the nasal septum go-plus.json vomer bone|prevomer http://purl.obolibrary.org/obo/UBERON_0002396 GO:0071674 biolink:BiologicalProcess mononuclear cell migration The movement of a mononuclear cell within or between different tissues and organs of the body. go-plus.json http://purl.obolibrary.org/obo/GO_0071674 GO:0071673 biolink:BiologicalProcess positive regulation of smooth muscle cell chemotaxis Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis. go-plus.json stimulation of smooth muscle cell chemotaxis|up-regulation of smooth muscle cell chemotaxis|upregulation of smooth muscle cell chemotaxis|up regulation of smooth muscle cell chemotaxis|activation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071673 GO:0071672 biolink:BiologicalProcess negative regulation of smooth muscle cell chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis. go-plus.json down-regulation of smooth muscle cell chemotaxis|inhibition of smooth muscle cell chemotaxis|down regulation of smooth muscle cell chemotaxis|downregulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071672 UBERON:0002398 biolink:AnatomicalEntity manus distal segment of the fore limb, including carpal region, metacarpal region and digits. go-plus.json fore paw|hand region|forelimb autopod|forelimb autopodium|fore-paw|forefoot of quadruped|fore foot|forefeet|forefoot|forepaw|hand|terminal segment of free upper limb http://purl.obolibrary.org/obo/UBERON_0002398 GO:1900579 biolink:BiologicalProcess (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol. go-plus.json (17Z)-protosta-17(20),24-dien-3beta-ol metabolism http://purl.obolibrary.org/obo/GO_1900579 GO:1900576 biolink:BiologicalProcess gerfelin metabolic process The chemical reactions and pathways involving gerfelin. go-plus.json gerfelin metabolism http://purl.obolibrary.org/obo/GO_1900576 CHEBI:35715 biolink:ChemicalSubstance nitro compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35715 GO:1900575 biolink:BiologicalProcess emodin biosynthetic process The chemical reactions and pathways resulting in the formation of emodin. go-plus.json emodin formation|emodin biosynthesis|emodin anabolism|emodin synthesis http://purl.obolibrary.org/obo/GO_1900575 CHEBI:35714 biolink:ChemicalSubstance polycyclic olefin go-plus.json http://purl.obolibrary.org/obo/CHEBI_35714 GO:1900578 biolink:BiologicalProcess gerfelin biosynthetic process The chemical reactions and pathways resulting in the formation of gerfelin. go-plus.json gerfelin synthesis|gerfelin formation|gerfelin biosynthesis|gerfelin anabolism http://purl.obolibrary.org/obo/GO_1900578 CHEBI:35717 biolink:ChemicalSubstance sedative go-plus.json http://purl.obolibrary.org/obo/CHEBI_35717 CHEBI:35716 biolink:ChemicalSubstance C-nitro compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35716 GO:1900577 biolink:BiologicalProcess gerfelin catabolic process The chemical reactions and pathways resulting in the breakdown of gerfelin. go-plus.json gerfelin catabolism|gerfelin degradation|gerfelin breakdown http://purl.obolibrary.org/obo/GO_1900577 GO:1900572 biolink:BiologicalProcess diorcinol biosynthetic process The chemical reactions and pathways resulting in the formation of diorcinol. go-plus.json diorcinol synthesis|diorcinol biosynthesis|diorcinol formation|diorcinol anabolism http://purl.obolibrary.org/obo/GO_1900572 CHEBI:35719 biolink:ChemicalSubstance sulfamic acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_35719 GO:1900571 biolink:BiologicalProcess diorcinol catabolic process The chemical reactions and pathways resulting in the breakdown of diorcinol. go-plus.json diorcinol catabolism|diorcinol degradation|diorcinol breakdown http://purl.obolibrary.org/obo/GO_1900571 CHEBI:35718 biolink:ChemicalSubstance antifungal agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35718 GO:1900574 biolink:BiologicalProcess emodin catabolic process The chemical reactions and pathways resulting in the breakdown of emodin. go-plus.json emodin catabolism|emodin degradation|emodin breakdown http://purl.obolibrary.org/obo/GO_1900574 GO:1900573 biolink:BiologicalProcess emodin metabolic process The chemical reactions and pathways involving emodin. go-plus.json emodin metabolism http://purl.obolibrary.org/obo/GO_1900573 CL:2000019 biolink:Cell compound eye photoreceptor cell Any photoreceptor cell that is part of a compound eye. go-plus.json http://purl.obolibrary.org/obo/CL_2000019 GO:1900581 biolink:BiologicalProcess (17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol. go-plus.json (17Z)-protosta-17(20),24-dien-3beta-ol biosynthesis|(17Z)-protosta-17(20),24-dien-3beta-ol anabolism|(17Z)-protosta-17(20),24-dien-3beta-ol synthesis|(17Z)-protosta-17(20),24-dien-3beta-ol formation http://purl.obolibrary.org/obo/GO_1900581 UBERON:0002384 biolink:AnatomicalEntity connective tissue Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. go-plus.json Bindegewebe|portion of connective tissue|textus connectivus http://purl.obolibrary.org/obo/UBERON_0002384 GO:1900580 biolink:BiologicalProcess (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol. go-plus.json (17Z)-protosta-17(20),24-dien-3beta-ol degradation|(17Z)-protosta-17(20),24-dien-3beta-ol breakdown|(17Z)-protosta-17(20),24-dien-3beta-ol catabolism http://purl.obolibrary.org/obo/GO_1900580 CHEBI:35711 biolink:ChemicalSubstance ursane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35711 chebi_ph7_3 CHEBI:35710 biolink:ChemicalSubstance pinane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35710 chebi_ph7_3 CL:2000018 biolink:Cell endothelial cell of coronary artery Any endothelial cell of artery that is part of a coronary artery. go-plus.json http://purl.obolibrary.org/obo/CL_2000018 UBERON:0002380 biolink:AnatomicalEntity trapezius muscle A large superficial muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae and laterally to the spine of the scapula (shoulder blade). Its functions are to move the scapulae and support the arm. The trapezius has three functional regions: the superior region (descending part), which supports the weight of the arm; the intermediate region (transverse part), which retracts the scapulae; and the inferior region (ascending part), which medially rotates and depresses the scapulae. [WP,unvetted]. go-plus.json spinotrapezius|musculus trapezius|trapezius http://purl.obolibrary.org/obo/UBERON_0002380 CHEBI:35713 biolink:ChemicalSubstance polycyclic alkane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35713 UBERON:0002389 biolink:AnatomicalEntity manual digit A digit that is part of a manus (hand). go-plus.json hand digit|forelimb digit|fore digit|finger|manual digit (phalangeal portion) plus soft tissue|digit of hand|digitus manus|digit of manus http://purl.obolibrary.org/obo/UBERON_0002389 UBERON:0002386 biolink:AnatomicalEntity forelimb zeugopod The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants. go-plus.json zeugopod of brachial region|antebrachial region|arm zeugopod|middle limb segment of proximal segment of free upper limb|zeugopod of proximal segment of free upper limb|fore epipodium|intermediate segment of free upper limb|wing zeugopod|antibrachium|regio antebrachialis|arm middle limb segment|forelimb zygopod|zeugopod of forelimb|antebrachium|forelimb epipodium|middle limb segment of forelimb|brachial region middle limb segment|antebrachium|middle limb segment of arm|zeugopod of arm|forearm|lower segment of arm|brachial region zeugopod|lower arm|middle limb segment of brachial region|forelimb zeugopodium http://purl.obolibrary.org/obo/UBERON_0002386 UBERON:0002385 biolink:AnatomicalEntity muscle tissue Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. go-plus.json muscular tissue|portion of muscle tissue|textus muscularis http://purl.obolibrary.org/obo/UBERON_0002385 UBERON:0002387 biolink:AnatomicalEntity pes distal portion of the hind limb, including tarsal region, metatarsal region and digits. go-plus.json hind-paw|hindpaw|foot|terminal segment of free lower limb|hind limb autopodium|hindfoot|hindfeet|hind paw|hindlimb autopodium|hindlimb distal free limb segment|hindlimb autopod|pes|hind foot|hindfoot of quadruped http://purl.obolibrary.org/obo/UBERON_0002387 GO:0071693 biolink:BiologicalProcess protein transport within extracellular region The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0071693 GO:0071692 biolink:BiologicalProcess protein localization to extracellular region Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. go-plus.json protein localisation in extracellular region|protein localization in extracellular region http://purl.obolibrary.org/obo/GO_0071692 GO:0071691 biolink:BiologicalProcess cardiac muscle thin filament assembly The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0071691 GO:0071690 biolink:BiologicalProcess cardiac muscle myosin thick filament assembly The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle. go-plus.json http://purl.obolibrary.org/obo/GO_0071690 PR:000045358 biolink:Protein insulin family protein A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide. go-plus.json fam:INS http://purl.obolibrary.org/obo/PR_000045358 GO:1900587 biolink:BiologicalProcess arugosin biosynthetic process The chemical reactions and pathways resulting in the formation of arugosin. go-plus.json arugosin biosynthesis|arugosin synthesis|arugosin formation|arugosin anabolism http://purl.obolibrary.org/obo/GO_1900587 CHEBI:35725 biolink:ChemicalSubstance isopropyl ester go-plus.json http://purl.obolibrary.org/obo/CHEBI_35725 chebi_ph7_3 GO:1900586 biolink:BiologicalProcess arugosin catabolic process The chemical reactions and pathways resulting in the breakdown of arugosin. go-plus.json arugosin degradation|arugosin breakdown|arugosin catabolism http://purl.obolibrary.org/obo/GO_1900586 CL:2000000 biolink:Cell epidermal melanocyte Any melanocyte that is part of a epidermis. go-plus.json http://purl.obolibrary.org/obo/CL_2000000 GO:1900589 biolink:BiologicalProcess violaceol I catabolic process The chemical reactions and pathways resulting in the breakdown of violaceol I. go-plus.json violaceol I degradation|violaceol I breakdown|violaceol I catabolism http://purl.obolibrary.org/obo/GO_1900589 UBERON:2000175 biolink:AnatomicalEntity posterior lateral line nerve Cranial nerve which enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines. go-plus.json caudal lateral line nerve http://purl.obolibrary.org/obo/UBERON_2000175 GO:1900588 biolink:BiologicalProcess violaceol I metabolic process The chemical reactions and pathways involving violaceol I. go-plus.json violaceol I metabolism http://purl.obolibrary.org/obo/GO_1900588 CHEBI:35727 biolink:ChemicalSubstance triazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_35727 GO:1900583 biolink:BiologicalProcess o-orsellinic acid catabolic process The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid. go-plus.json o-orsellinic acid degradation|o-orsellinic acid breakdown|o-orsellinic acid catabolism http://purl.obolibrary.org/obo/GO_1900583 GO:1900582 biolink:BiologicalProcess o-orsellinic acid metabolic process The chemical reactions and pathways involving o-orsellinic acid. go-plus.json o-orsellinic acid metabolism http://purl.obolibrary.org/obo/GO_1900582 GO:1900585 biolink:BiologicalProcess arugosin metabolic process The chemical reactions and pathways involving arugosin. go-plus.json arugosin metabolism http://purl.obolibrary.org/obo/GO_1900585 GO:1900584 biolink:BiologicalProcess o-orsellinic acid biosynthetic process The chemical reactions and pathways resulting in the formation of o-orsellinic acid. go-plus.json o-orsellinic acid biosynthesis|o-orsellinic acid synthesis|o-orsellinic acid formation|o-orsellinic acid anabolism http://purl.obolibrary.org/obo/GO_1900584 GO:1900590 biolink:BiologicalProcess violaceol I biosynthetic process The chemical reactions and pathways resulting in the formation of violaceol I. go-plus.json violaceol I synthesis|violaceol I formation|violaceol I biosynthesis|violaceol I anabolism http://purl.obolibrary.org/obo/GO_1900590 UBERON:0002371 biolink:AnatomicalEntity bone marrow the soft tissue that fills the cavities of bones go-plus.json medulla ossea|medulla of bone|medullary bone|medulla ossium http://purl.obolibrary.org/obo/UBERON_0002371 UBERON:0002370 biolink:AnatomicalEntity thymus Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop. go-plus.json thymus gland|thymus organ http://purl.obolibrary.org/obo/UBERON_0002370 GO:1900592 biolink:BiologicalProcess violaceol II catabolic process The chemical reactions and pathways resulting in the breakdown of violaceol II. go-plus.json violaceol II catabolism|violaceol II degradation|violaceol II breakdown http://purl.obolibrary.org/obo/GO_1900592 GO:1900591 biolink:BiologicalProcess violaceol II metabolic process The chemical reactions and pathways involving violaceol II. go-plus.json violaceol II metabolism http://purl.obolibrary.org/obo/GO_1900591 CL:2000005 biolink:Cell brain macroglial cell Any macroglial cell that is part of a brain. go-plus.json http://purl.obolibrary.org/obo/CL_2000005 CHEBI:35722 biolink:ChemicalSubstance sulfated glycosaminoglycan go-plus.json http://purl.obolibrary.org/obo/CHEBI_35722 CHEBI:35721 biolink:ChemicalSubstance heparan sulfates go-plus.json http://purl.obolibrary.org/obo/CHEBI_35721 CL:2000004 biolink:Cell pituitary gland cell Any cell that is part of a pituitary gland. go-plus.json http://purl.obolibrary.org/obo/CL_2000004 CHEBI:35724 biolink:ChemicalSubstance carbohydrate sulfate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35724 UBERON:0002378 biolink:AnatomicalEntity muscle of abdomen Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis. go-plus.json abdomen muscle|abdominal muscle|muscle organ of abdomen|abdominal wall musculature|abdominal wall muscle|abdomen muscle organ http://purl.obolibrary.org/obo/UBERON_0002378 GO:0071699 biolink:BiologicalProcess olfactory placode morphogenesis The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0071699 GO:0071698 biolink:BiologicalProcess olfactory placode development The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. go-plus.json http://purl.obolibrary.org/obo/GO_0071698 GO:0071697 biolink:BiologicalProcess ectodermal placode morphogenesis The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0071697 UBERON:0002374 biolink:AnatomicalEntity metacarpal bone A bone that is part of the metacarpal skeleton. go-plus.json metacarpal http://purl.obolibrary.org/obo/UBERON_0002374 GO:0071696 biolink:BiologicalProcess ectodermal placode development The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. go-plus.json http://purl.obolibrary.org/obo/GO_0071696 GO:0071695 biolink:BiologicalProcess anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. go-plus.json http://purl.obolibrary.org/obo/GO_0071695 UBERON:0002377 biolink:AnatomicalEntity muscle of neck Any muscle that is part of the cervical (neck) region. go-plus.json muscle organ of neck|neck muscle organ|muscle organ of neck (volume)|neck (volume) muscle organ|neck muscle http://purl.obolibrary.org/obo/UBERON_0002377 GO:0071694 biolink:BiologicalProcess maintenance of protein location in extracellular region Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere. go-plus.json http://purl.obolibrary.org/obo/GO_0071694 UBERON:0002376 biolink:AnatomicalEntity cranial muscle Any skeletal muscle that is part of the head region. go-plus.json muscle organ of head|cephalic musculature|adult head muscle organ|head muscle organ|musculus caput|head muscles|muscle of head|cranial muscle|cephalic muscle|head muscle|muscle organ of adult head http://purl.obolibrary.org/obo/UBERON_0002376 CHEBI:21099 biolink:ChemicalSubstance D-tagaturonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21099 GO:1900914 biolink:BiologicalProcess regulation of octadecene biosynthetic process Any process that modulates the frequency, rate or extent of octadecene biosynthetic process. go-plus.json regulation of octadecene anabolism|regulation of octadecene synthesis|regulation of 1-octadecene biosynthetic process|regulation of octadecene formation|regulation of octadecene biosynthesis http://purl.obolibrary.org/obo/GO_1900914 GO:1900913 biolink:BiologicalProcess positive regulation of olefin biosynthetic process Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process. go-plus.json up regulation of olefin biosynthetic process|positive regulation of olefin anabolism|activation of olefin biosynthesis|activation of olefin biosynthetic process|up regulation of olefin anabolism|positive regulation of olefin synthesis|up regulation of olefin biosynthesis|up regulation of olefin synthesis|positive regulation of olefin biosynthesis|positive regulation of olefin formation|up regulation of olefin formation|upregulation of olefin anabolism|up-regulation of olefin biosynthetic process|upregulation of olefin synthesis|activation of olefin anabolism|up-regulation of olefin biosynthesis|upregulation of olefin formation|activation of olefin synthesis|up-regulation of olefin anabolism|upregulation of olefin biosynthetic process|activation of olefin formation|up-regulation of olefin synthesis|upregulation of olefin biosynthesis|up-regulation of olefin formation http://purl.obolibrary.org/obo/GO_1900913 GO:1900916 biolink:BiologicalProcess positive regulation of octadecene biosynthetic process Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process. go-plus.json up-regulation of octadecene anabolism|positive regulation of octadecene biosynthesis|activation of 1-octadecene biosynthetic process|up-regulation of octadecene synthesis|activation of octadecene anabolism|activation of octadecene biosynthesis|up-regulation of octadecene formation|up-regulation of octadecene biosynthetic process|up-regulation of 1-octadecene biosynthetic process|activation of octadecene synthesis|positive regulation of octadecene anabolism|up-regulation of octadecene biosynthesis|activation of octadecene formation|up regulation of octadecene anabolism|positive regulation of octadecene synthesis|upregulation of octadecene biosynthetic process|up regulation of octadecene synthesis|upregulation of 1-octadecene biosynthetic process|positive regulation of octadecene formation|up regulation of octadecene formation|upregulation of octadecene biosynthesis|upregulation of octadecene anabolism|up regulation of octadecene biosynthetic process|upregulation of octadecene synthesis|activation of octadecene biosynthetic process|up regulation of 1-octadecene biosynthetic process|positive regulation of 1-octadecene biosynthetic process|upregulation of octadecene formation|up regulation of octadecene biosynthesis http://purl.obolibrary.org/obo/GO_1900916 GO:0022871 biolink:MolecularActivity protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. EC:2.7.1.206|RHEA:49296 go-plus.json sorbose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022871 CHEBI:45064 biolink:ChemicalSubstance phosphite(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_45064 GO:1900915 biolink:BiologicalProcess negative regulation of octadecene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process. go-plus.json down-regulation of 1-octadecene biosynthetic process|negative regulation of 1-octadecene biosynthetic process|inhibition of 1-octadecene biosynthetic process|negative regulation of octadecene biosynthesis|down-regulation of octadecene biosynthesis|inhibition of octadecene biosynthetic process|down-regulation of octadecene anabolism|negative regulation of octadecene anabolism|inhibition of octadecene biosynthesis|down-regulation of octadecene synthesis|negative regulation of octadecene synthesis|down-regulation of octadecene formation|negative regulation of octadecene formation|downregulation of octadecene anabolism|inhibition of octadecene anabolism|down regulation of octadecene biosynthetic process|downregulation of octadecene synthesis|down regulation of octadecene anabolism|down regulation of 1-octadecene biosynthetic process|inhibition of octadecene synthesis|downregulation of octadecene formation|downregulation of octadecene biosynthetic process|downregulation of 1-octadecene biosynthetic process|down regulation of octadecene synthesis|down regulation of octadecene biosynthesis|inhibition of octadecene formation|down regulation of octadecene formation|downregulation of octadecene biosynthesis|down-regulation of octadecene biosynthetic process http://purl.obolibrary.org/obo/GO_1900915 GO:0022870 biolink:MolecularActivity protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json mannose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022870 GO:1900910 biolink:BiologicalProcess positive regulation of olefin metabolic process Any process that activates or increases the frequency, rate or extent of olefin metabolic process. go-plus.json activation of olefin metabolism|up-regulation of olefin metabolic process|activation of olefin metabolic process|up regulation of olefin metabolism|positive regulation of olefin metabolism|up regulation of olefin metabolic process|up-regulation of olefin metabolism|upregulation of olefin metabolic process|upregulation of olefin metabolism http://purl.obolibrary.org/obo/GO_1900910 GO:0022873 biolink:MolecularActivity protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json maltose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022873 GO:0022872 biolink:MolecularActivity protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json mannitol PTS transporter activity http://purl.obolibrary.org/obo/GO_0022872 GO:0007239 biolink:BiologicalProcess obsolete activation of Hog1 OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of Hog1 http://purl.obolibrary.org/obo/GO_0007239 GO:1900912 biolink:BiologicalProcess negative regulation of olefin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process. go-plus.json down-regulation of olefin synthesis|negative regulation of olefin synthesis|downregulation of olefin biosynthesis|down-regulation of olefin formation|negative regulation of olefin formation|down-regulation of olefin biosynthetic process|inhibition of olefin anabolism|downregulation of olefin anabolism|inhibition of olefin synthesis|downregulation of olefin synthesis|down regulation of olefin anabolism|down-regulation of olefin biosynthesis|negative regulation of olefin biosynthesis|inhibition of olefin biosynthesis|inhibition of olefin biosynthetic process|downregulation of olefin formation|inhibition of olefin formation|down regulation of olefin synthesis|down regulation of olefin formation|down regulation of olefin biosynthetic process|down-regulation of olefin anabolism|downregulation of olefin biosynthetic process|negative regulation of olefin anabolism|down regulation of olefin biosynthesis http://purl.obolibrary.org/obo/GO_1900912 GO:0022875 biolink:MolecularActivity protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json galactitol PTS transporter activity http://purl.obolibrary.org/obo/GO_0022875 GO:0007238 biolink:BiologicalProcess obsolete activation of Pbs2 OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of Pbs2 http://purl.obolibrary.org/obo/GO_0007238 GO:1900911 biolink:BiologicalProcess regulation of olefin biosynthetic process Any process that modulates the frequency, rate or extent of olefin biosynthetic process. go-plus.json regulation of olefin anabolism|regulation of olefin synthesis|regulation of olefin formation|regulation of olefin biosynthesis http://purl.obolibrary.org/obo/GO_1900911 GO:0022874 biolink:MolecularActivity protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json cellobiose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022874 GO:0007237 biolink:BiologicalProcess obsolete activation of Ssk2/Ssk22 proteins OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of Ssk2/Ssk22 proteins http://purl.obolibrary.org/obo/GO_0007237 GO:0007236 biolink:BiologicalProcess obsolete activation of Ssk1 protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of Ssk1 protein http://purl.obolibrary.org/obo/GO_0007236 GO:0046844 biolink:BiologicalProcess chorion micropyle formation Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization. go-plus.json http://purl.obolibrary.org/obo/GO_0046844 GO:0046843 biolink:BiologicalProcess dorsal appendage formation Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration. go-plus.json http://purl.obolibrary.org/obo/GO_0046843 GO:0007235 biolink:BiologicalProcess obsolete activation of Ypd1 protein OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of Ypd1 protein http://purl.obolibrary.org/obo/GO_0007235 GO:0046842 biolink:BiologicalProcess trisporic acid biosynthetic process The chemical reactions and pathways resulting in the formation of trisporic acid. go-plus.json trisporic acid anabolism|trisporic acid synthesis|trisporic acid formation|trisporic acid biosynthesis http://purl.obolibrary.org/obo/GO_0046842 GO:0007234 biolink:BiologicalProcess osmosensory signaling via phosphorelay pathway A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system. go-plus.json signal transduction during osmotic stress via two-component system|osmolarity sensing via two-component system|osmosensory signalling pathway via two-component system|osmolarity signalling pathway via two-component system|osmosensory signaling pathway via two-component system|osmolarity signaling pathway via two-component system http://purl.obolibrary.org/obo/GO_0007234 GO:0046841 biolink:BiologicalProcess trisporic acid metabolic process The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota. go-plus.json trisporic acid metabolism http://purl.obolibrary.org/obo/GO_0046841 GO:0007233 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007233 GO:0007232 biolink:BiologicalProcess osmosensory signaling pathway via Sho1 osmosensor A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system. go-plus.json osmosensory signalling pathway via Sho1 osmosensor|signal transduction during osmotic stress via Sho1 osmosensor http://purl.obolibrary.org/obo/GO_0007232 GO:0046840 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046840 GO:0007231 biolink:BiologicalProcess osmosensory signaling pathway The series of molecular signals initiated in response to osmotic change. go-plus.json osmolarity sensing signalling pathway|osmolarity sensing signaling pathway|osmosensory signal transduction|osmolarity sensing|signal transduction during osmotic stress|osmosensory signalling pathway http://purl.obolibrary.org/obo/GO_0007231 CHEBI:84666 biolink:ChemicalSubstance (25S)-3-oxocholest-4-en-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84666 GO:0007230 biolink:BiologicalProcess obsolete calcium-o-sensing receptor pathway OBSOLETE. (Was not defined before being made obsolete). go-plus.json calcium-o-sensing receptor pathway http://purl.obolibrary.org/obo/GO_0007230 CHEBI:84665 biolink:ChemicalSubstance triacylglycerol 50:1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84665 chebi_ph7_3 GO:0071808 biolink:CellularComponent satellite fibril An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section). go-plus.json http://purl.obolibrary.org/obo/GO_0071808 GO:0071807 biolink:BiologicalProcess replication fork arrest involved in DNA replication termination A replication fork arrest process that contributes to the termination of DNA replication. go-plus.json http://purl.obolibrary.org/obo/GO_0071807 GO:0071806 biolink:BiologicalProcess protein transmembrane transport The process in which a protein is transported across a membrane. go-plus.json protein membrane transport http://purl.obolibrary.org/obo/GO_0071806 goslim_drosophila GO:0046849 biolink:BiologicalProcess bone remodeling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. Wikipedia:Bone_remodeling go-plus.json bone remodelling http://purl.obolibrary.org/obo/GO_0046849 GO:0071805 biolink:BiologicalProcess potassium ion transmembrane transport A process in which a potassium ion is transported from one side of a membrane to the other. go-plus.json high-affinity potassium ion import|high affinity potassium ion uptake|high affinity potassium ion import|high-affinity potassium ion uptake|potassium ion membrane transport http://purl.obolibrary.org/obo/GO_0071805 GO:0071804 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071804 GO:0046848 biolink:MolecularActivity hydroxyapatite binding Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin. go-plus.json hydroxylapatite binding http://purl.obolibrary.org/obo/GO_0046848 GO:0071803 biolink:BiologicalProcess positive regulation of podosome assembly Any process that activates or increases the rate or extent of podosome assembly. go-plus.json upregulation of podosome assembly|up regulation of podosome assembly|activation of podosome assembly|stimulation of podosome assembly|up-regulation of podosome assembly http://purl.obolibrary.org/obo/GO_0071803 GO:0046847 biolink:BiologicalProcess filopodium assembly The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. go-plus.json filopodia biosynthesis|filopodia formation|filopodium formation http://purl.obolibrary.org/obo/GO_0046847 GO:0071802 biolink:BiologicalProcess negative regulation of podosome assembly Any process that stops, prevents or reduces the rate or extent of podosome assembly. go-plus.json down regulation of podosome assembly|downregulation of podosome assembly|down-regulation of podosome assembly|inhibition of podosome assembly http://purl.obolibrary.org/obo/GO_0071802 GO:0046846 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046846 CHEBI:142734 biolink:ChemicalSubstance N-acyl hemiaminal go-plus.json http://purl.obolibrary.org/obo/CHEBI_142734 chebi_ph7_3 GO:0046845 biolink:BiologicalProcess branched duct epithelial cell fate determination, open tracheal system Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode. go-plus.json branch cell fate determination http://purl.obolibrary.org/obo/GO_0046845 GO:0071801 biolink:BiologicalProcess regulation of podosome assembly Any process that modulates the frequency, rate or extent of podosome assembly. go-plus.json http://purl.obolibrary.org/obo/GO_0071801 GO:0071800 biolink:BiologicalProcess podosome assembly The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell. go-plus.json http://purl.obolibrary.org/obo/GO_0071800 GO:0022877 biolink:MolecularActivity protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json fructose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022877 GO:0022876 biolink:MolecularActivity protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json galactosamine PTS transporter activity http://purl.obolibrary.org/obo/GO_0022876 GO:0022879 biolink:MolecularActivity protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json trehalose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022879 GO:0022878 biolink:MolecularActivity protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. MetaCyc:SUCROSEPHOSPHO-RXN|RHEA:49236 go-plus.json sucrose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022878 GO:1900918 biolink:BiologicalProcess negative regulation of octadecene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process. go-plus.json downregulation of octadecene metabolic process|down regulation of octadecene metabolic process|inhibition of octadecene metabolic process|down-regulation of octadecene metabolism|negative regulation of octadecene metabolism|inhibition of octadecene metabolism|down-regulation of octadecene metabolic process|down regulation of octadecene metabolism|downregulation of octadecene metabolism http://purl.obolibrary.org/obo/GO_1900918 GO:1900917 biolink:BiologicalProcess regulation of octadecene metabolic process Any process that modulates the frequency, rate or extent of octadecene metabolic process. go-plus.json regulation of octadecene metabolism http://purl.obolibrary.org/obo/GO_1900917 GO:1900919 biolink:BiologicalProcess positive regulation of octadecene metabolic process Any process that activates or increases the frequency, rate or extent of octadecene metabolic process. go-plus.json activation of octadecene metabolism|up regulation of octadecene metabolism|positive regulation of octadecene metabolism|upregulation of octadecene metabolic process|up-regulation of octadecene metabolism|up-regulation of octadecene metabolic process|activation of octadecene metabolic process|upregulation of octadecene metabolism|up regulation of octadecene metabolic process http://purl.obolibrary.org/obo/GO_1900919 GO:1900925 biolink:BiologicalProcess positive regulation of glycine import across plasma membrane Any process that activates or increases the frequency, rate or extent of glycine import. go-plus.json up-regulation of glycine import|activation of glycine import|positive regulation of glycine import|up regulation of glycine import|upregulation of glycine import http://purl.obolibrary.org/obo/GO_1900925 GO:1900924 biolink:BiologicalProcess negative regulation of glycine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell. go-plus.json negative regulation of glycine import|down-regulation of glycine import|downregulation of glycine import|down regulation of glycine import|inhibition of glycine import http://purl.obolibrary.org/obo/GO_1900924 GO:1900927 biolink:BiologicalProcess negative regulation of L-threonine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell. go-plus.json downregulation of L-threonine import|down regulation of L-threonine import|inhibition of L-threonine import|downregulation of L-threonine uptake|inhibition of L-threonine uptake|down regulation of L-threonine uptake|down-regulation of L-threonine import|negative regulation of L-threonine uptake|down-regulation of L-threonine uptake http://purl.obolibrary.org/obo/GO_1900927 CHEBI:70031 biolink:ChemicalSubstance 2'-hydroxygenistein go-plus.json http://purl.obolibrary.org/obo/CHEBI_70031 GO:1900926 biolink:BiologicalProcess regulation of L-threonine import across plasma membrane Any process that modulates the frequency, rate or extent of L-threonine import into cell. go-plus.json regulation of L-threonine uptake|regulation of L-threonine import http://purl.obolibrary.org/obo/GO_1900926 GO:1900921 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900921 GO:1900920 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900920 GO:1900923 biolink:BiologicalProcess regulation of glycine import across plasma membrane Any process that modulates the frequency, rate or extent of glycine import into a cell. go-plus.json regulation of glycine import http://purl.obolibrary.org/obo/GO_1900923 GO:0007249 biolink:BiologicalProcess I-kappaB kinase/NF-kappaB signaling The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. go-plus.json NF-kappaB cascade|I-kappaB kinase/NF-kappaB signal transduction|I-kappaB kinase/NF-kappaB cascade|p50-dependent NF-kappaB signaling|canonical NF-kappaB signaling cascade|activation of the inhibitor of kappa kinase http://purl.obolibrary.org/obo/GO_0007249 CHEBI:69042 biolink:ChemicalSubstance 7-demethylsuberosin go-plus.json http://purl.obolibrary.org/obo/CHEBI_69042 chebi_ph7_3 GO:0007248 biolink:BiologicalProcess obsolete nuclear translocation of MAPK (mating sensu Saccharomyces) OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces. go-plus.json nuclear translocation of MAPK (mating sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007248 SO:0001240 biolink:SequenceFeature TSS_region The region of a gene from the 5' most TSS to the 3' TSS. go-plus.json TSS region http://purl.obolibrary.org/obo/SO_0001240 GO:1900922 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900922 GO:0007247 biolink:BiologicalProcess obsolete activation of MAPK (mating sensu Saccharomyces) OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. go-plus.json activation of MAPK (mating sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007247 GO:0046855 biolink:BiologicalProcess inositol phosphate dephosphorylation The process of removing a phosphate group from any mono- or polyphosphorylated inositol. go-plus.json myo-inositol phosphate dephosphorylation http://purl.obolibrary.org/obo/GO_0046855 GO:0007246 biolink:BiologicalProcess obsolete activation of MAPKK (mating sensu Saccharomyces) OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces. go-plus.json activation of MAPKK (mating sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007246 GO:0046854 biolink:BiologicalProcess phosphatidylinositol phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. go-plus.json PIP biosynthesis|phosphatidylinositol phosphate phosphorylation|phosphatidylinositol phosphate biosynthetic process|phosphoinositide phosphorylation|phosphatidylinositol phosphorylation|PtdInsP biosynthesis|phosphatidylinositol phosphate biosynthesis http://purl.obolibrary.org/obo/GO_0046854 GO:0007245 biolink:BiologicalProcess obsolete activation of MAPKKK (mating sensu Saccharomyces) OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. go-plus.json activation of MAPKKK (mating sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007245 GO:0046853 biolink:BiologicalProcess obsolete inositol or phosphatidylinositol phosphorylation OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms. go-plus.json myo-inositol and derivative phosphorylation|myo-inositol or phosphatidyl-myo-inositol phosphorylation|inositol and derivative phosphorylation|inositol or phosphatidylinositol phosphorylation http://purl.obolibrary.org/obo/GO_0046853 GO:0007244 biolink:BiologicalProcess obsolete MAPKKK cascade (mating sensu Saccharomyces) OBSOLETE. MAPKKK cascade involved in transduction of mating pheromone signal, as described in Saccharomyces. go-plus.json MAPKKK cascade (mating sensu Saccharomyces) http://purl.obolibrary.org/obo/GO_0007244 GO:0046852 biolink:BiologicalProcess positive regulation of bone remodeling Any process that activates or increases the frequency, rate or extent of bone remodeling. go-plus.json upregulation of bone remodeling|up regulation of bone remodeling|activation of bone remodeling|stimulation of bone remodeling|up-regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046852 GO:0046851 biolink:BiologicalProcess negative regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. go-plus.json down regulation of bone remodeling|downregulation of bone remodeling|down-regulation of bone remodeling|inhibition of bone remodeling http://purl.obolibrary.org/obo/GO_0046851 GO:0007243 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007243 GO:0046850 biolink:BiologicalProcess regulation of bone remodeling Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. go-plus.json http://purl.obolibrary.org/obo/GO_0046850 GO:0007242 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007242 GO:0007241 biolink:BiologicalProcess obsolete inactivation of Hog1 OBSOLETE. (Was not defined before being made obsolete). go-plus.json inactivation of Hog1 http://purl.obolibrary.org/obo/GO_0007241 GO:0007240 biolink:BiologicalProcess obsolete nuclear translocation of Hog1 OBSOLETE. (Was not defined before being made obsolete). go-plus.json nuclear translocation of Hog1 http://purl.obolibrary.org/obo/GO_0007240 CHEBI:84675 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84675 GO:0007250 biolink:BiologicalProcess activation of NF-kappaB-inducing kinase activity The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues. go-plus.json positive regulation of NF-kappaB-inducing kinase activity|activation of NIK activity http://purl.obolibrary.org/obo/GO_0007250 CHEBI:59696 biolink:ChemicalSubstance steroid sulfate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59696 CHEBI:84672 biolink:ChemicalSubstance phosphatidylethanol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84672 chebi_ph7_3 GO:0046859 biolink:CellularComponent hydrogenosomal membrane The lipid bilayer surrounding a hydrogenosome. go-plus.json hydrogenosome membrane http://purl.obolibrary.org/obo/GO_0046859 GO:0046858 biolink:CellularComponent chlorosome A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate. Wikipedia:Chlorosome go-plus.json http://purl.obolibrary.org/obo/GO_0046858 GO:0046857 biolink:MolecularActivity oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP. EC:1.7.1.- go-plus.json http://purl.obolibrary.org/obo/GO_0046857 GO:0046856 biolink:BiologicalProcess phosphatidylinositol dephosphorylation The process of removing one or more phosphate groups from a phosphatidylinositol. go-plus.json PIP catabolism|phosphatidylinositol phosphate dephosphorylation|PtdInsP catabolism|PtdInsP dephosphorylation|phosphatidylinositol phosphate catabolic process|phosphoinositide dephosphorylation http://purl.obolibrary.org/obo/GO_0046856 GO:0022866 biolink:MolecularActivity obsolete transmembrane 1-electron transfer carrier OBSOLETE. Enables transfer of one electron across a membrane. go-plus.json transmembrane one-electron transfer carrier http://purl.obolibrary.org/obo/GO_0022866 GO:0022865 biolink:MolecularActivity obsolete transmembrane electron transfer carrier OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics. TC:5 go-plus.json http://purl.obolibrary.org/obo/GO_0022865 GO:0022867 biolink:MolecularActivity obsolete transmembrane 2-electron transfer carrier OBSOLETE. Enables transfer of two electrons across a membrane. go-plus.json transmembrane two-electron transfer carrier http://purl.obolibrary.org/obo/GO_0022867 GO:1900929 biolink:BiologicalProcess regulation of L-tyrosine import across plasma membrane Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell. go-plus.json regulation of L-tyrosine uptake|regulation of L-tyrosine import http://purl.obolibrary.org/obo/GO_1900929 SO:0001236 biolink:SequenceFeature base A base is a sequence feature that corresponds to a single unit of a nucleotide polymer. http://en.wikipedia.org/wiki/Nucleobase go-plus.json http://purl.obolibrary.org/obo/SO_0001236 SOFA GO:1900928 biolink:BiologicalProcess positive regulation of L-threonine import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-threonine import into cell. go-plus.json positive regulation of L-threonine uptake|up regulation of L-threonine uptake|upregulation of L-threonine import|upregulation of L-threonine uptake|up-regulation of L-threonine import|activation of L-threonine import|activation of L-threonine uptake|positive regulation of L-threonine import|up-regulation of L-threonine uptake|up regulation of L-threonine import http://purl.obolibrary.org/obo/GO_1900928 GO:0022869 biolink:MolecularActivity protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json lactose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022869 CHEBI:59699 biolink:ChemicalSubstance N,N-dihydroxy-alpha-amino-acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59699 CHEBI:59698 biolink:ChemicalSubstance phosphoric acids go-plus.json http://purl.obolibrary.org/obo/CHEBI_59698 GO:1900936 biolink:BiologicalProcess negative regulation of nonadec-1-ene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process. go-plus.json inhibition of nonadec-1-ene anabolism|inhibition of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene biosynthetic process|negative regulation of nonadec-1-ene biosynthesis|down-regulation of nonadec-1-ene biosynthesis|inhibition of nonadec-1-ene formation|down regulation of nonadec-1-ene anabolism|downregulation of nonadec-1-ene anabolism|down regulation of nonadec-1-ene synthesis|down regulation of nonadec-1-ene formation|downregulation of nonadec-1-ene biosynthesis|downregulation of nonadec-1-ene biosynthetic process|downregulation of nonadec-1-ene synthesis|downregulation of nonadec-1-ene formation|down regulation of nonadec-1-ene biosynthesis|down regulation of nonadec-1-ene biosynthetic process|negative regulation of nonadec-1-ene anabolism|down-regulation of nonadec-1-ene anabolism|inhibition of nonadec-1-ene biosynthetic process|negative regulation of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene synthesis|inhibition of nonadec-1-ene biosynthesis|negative regulation of nonadec-1-ene formation|down-regulation of nonadec-1-ene formation http://purl.obolibrary.org/obo/GO_1900936 CHEBI:21077 biolink:ChemicalSubstance D-ribonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21077 GO:1900935 biolink:BiologicalProcess regulation of nonadec-1-ene biosynthetic process Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process. go-plus.json regulation of nonadec-1-ene anabolism|regulation of nonadec-1-ene synthesis|regulation of nonadec-1-ene formation|regulation of nonadec-1-ene biosynthesis http://purl.obolibrary.org/obo/GO_1900935 GO:1900938 biolink:BiologicalProcess regulation of (Z)-nonadeca-1,14-diene metabolic process Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process. go-plus.json regulation of (Z)-nonadeca-1,14-diene metabolism http://purl.obolibrary.org/obo/GO_1900938 GO:1900937 biolink:BiologicalProcess positive regulation of nonadec-1-ene biosynthetic process Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process. go-plus.json activation of nonadec-1-ene biosynthetic process|up-regulation of nonadec-1-ene formation|upregulation of nonadec-1-ene anabolism|activation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene synthesis|positive regulation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene formation|up regulation of nonadec-1-ene biosynthesis|up regulation of nonadec-1-ene biosynthetic process|up regulation of nonadec-1-ene anabolism|positive regulation of nonadec-1-ene anabolism|up regulation of nonadec-1-ene synthesis|positive regulation of nonadec-1-ene synthesis|up regulation of nonadec-1-ene formation|activation of nonadec-1-ene anabolism|upregulation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene biosynthetic process|positive regulation of nonadec-1-ene formation|activation of nonadec-1-ene synthesis|up-regulation of nonadec-1-ene anabolism|activation of nonadec-1-ene formation|up-regulation of nonadec-1-ene biosynthetic process|up-regulation of nonadec-1-ene biosynthesis|up-regulation of nonadec-1-ene synthesis http://purl.obolibrary.org/obo/GO_1900937 GO:0007219 biolink:BiologicalProcess Notch signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Wikipedia:Notch_signaling_pathway go-plus.json Notch receptor signaling pathway|Notch receptor signalling pathway|N signalling pathway|Notch-receptor signalling pathway|Notch-receptor signaling pathway|N signaling pathway|Notch signalling pathway http://purl.obolibrary.org/obo/GO_0007219 GO:1900932 biolink:BiologicalProcess regulation of nonadec-1-ene metabolic process Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process. go-plus.json regulation of nonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900932 GO:0007218 biolink:BiologicalProcess neuropeptide signaling pathway The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor. go-plus.json neuropeptide signalling pathway http://purl.obolibrary.org/obo/GO_0007218 GO:0022851 biolink:MolecularActivity GABA-gated chloride ion channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0022851 GO:1900931 biolink:BiologicalProcess positive regulation of L-tyrosine import across plasma membrane Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell. go-plus.json up-regulation of L-tyrosine uptake|upregulation of L-tyrosine import|positive regulation of L-tyrosine import|upregulation of L-tyrosine uptake|up regulation of L-tyrosine import|activation of L-tyrosine import|activation of L-tyrosine uptake|up regulation of L-tyrosine uptake|positive regulation of L-tyrosine uptake|up-regulation of L-tyrosine import http://purl.obolibrary.org/obo/GO_1900931 GO:0007217 biolink:BiologicalProcess tachykinin receptor signaling pathway The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor. go-plus.json tachykinin signalling pathway http://purl.obolibrary.org/obo/GO_0007217 GO:0022850 biolink:MolecularActivity serotonin-gated cation-selective channel activity Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts. Reactome:R-HSA-9648983|Reactome:R-HSA-975311 go-plus.json 5-hydroxytryptamine-gated receptor-channel|serotonin-activated cation-selective channel activity|serotonin-gated cation channel activity http://purl.obolibrary.org/obo/GO_0022850 GO:1900934 biolink:BiologicalProcess positive regulation of nonadec-1-ene metabolic process Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process. go-plus.json up-regulation of nonadec-1-ene metabolism|up regulation of nonadec-1-ene metabolic process|activation of nonadec-1-ene metabolic process|activation of nonadec-1-ene metabolism|positive regulation of nonadec-1-ene metabolism|up regulation of nonadec-1-ene metabolism|up-regulation of nonadec-1-ene metabolic process|upregulation of nonadec-1-ene metabolism|upregulation of nonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900934 GO:0007216 biolink:BiologicalProcess G protein-coupled glutamate receptor signaling pathway A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json metabotropic glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor signalling pathway http://purl.obolibrary.org/obo/GO_0007216 GO:0022853 biolink:MolecularActivity active ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction. go-plus.json http://purl.obolibrary.org/obo/GO_0022853 GO:0022852 biolink:MolecularActivity glycine-gated chloride ion channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0022852 GO:0007215 biolink:BiologicalProcess glutamate receptor signaling pathway A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json glutamate signalling pathway|glutamate signaling pathway http://purl.obolibrary.org/obo/GO_0007215 GO:1900933 biolink:BiologicalProcess negative regulation of nonadec-1-ene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process. go-plus.json down-regulation of nonadec-1-ene metabolism|down-regulation of nonadec-1-ene metabolic process|negative regulation of nonadec-1-ene metabolism|inhibition of nonadec-1-ene metabolic process|downregulation of nonadec-1-ene metabolism|down regulation of nonadec-1-ene metabolism|down regulation of nonadec-1-ene metabolic process|inhibition of nonadec-1-ene metabolism|downregulation of nonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900933 GO:0007214 biolink:BiologicalProcess gamma-aminobutyric acid signaling pathway The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor. go-plus.json 4-aminobutyrate signalling pathway|gamma-aminobutyric acid signalling pathway|4-aminobutyrate signaling pathway|GABA signaling pathway|4-aminobutanoate signalling pathway|4-aminobutanoate signaling pathway|GABA signalling pathway http://purl.obolibrary.org/obo/GO_0007214 GO:0046866 biolink:BiologicalProcess tetraterpenoid transport The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units. go-plus.json http://purl.obolibrary.org/obo/GO_0046866 GO:0007213 biolink:BiologicalProcess G protein-coupled acetylcholine receptor signaling pathway Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription. go-plus.json G-protein coupled acetylcholine receptor signaling pathway|acetylcholine receptor signalling, muscarinic pathway|muscarinic acetylcholine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007213 GO:0046865 biolink:BiologicalProcess terpenoid transport The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups. go-plus.json http://purl.obolibrary.org/obo/GO_0046865 GO:1900930 biolink:BiologicalProcess negative regulation of L-tyrosine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell. go-plus.json down regulation of L-tyrosine import|inhibition of L-tyrosine uptake|downregulation of L-tyrosine import|down regulation of L-tyrosine uptake|negative regulation of L-tyrosine import|downregulation of L-tyrosine uptake|down-regulation of L-tyrosine import|inhibition of L-tyrosine import|down-regulation of L-tyrosine uptake|negative regulation of L-tyrosine uptake http://purl.obolibrary.org/obo/GO_1900930 GO:0046864 biolink:BiologicalProcess isoprenoid transport The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. go-plus.json http://purl.obolibrary.org/obo/GO_0046864 goslim_pir GO:0007212 biolink:BiologicalProcess dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. go-plus.json dopamine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0007212 GO:0046863 biolink:MolecularActivity ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate. go-plus.json rubisco activator|ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity|ribulose-bisphosphate carboxylase activase activity|rubisco activase activity http://purl.obolibrary.org/obo/GO_0046863 GO:0007211 biolink:BiologicalProcess octopamine or tyramine signaling pathway The series of molecular signals generated as a consequence of octopamine or tyramine binding to a cell surface receptor. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters. go-plus.json octopamine/tyramine signaling pathway|octopamine or tyramine signalling pathway http://purl.obolibrary.org/obo/GO_0007211 CHEBI:45049 biolink:ChemicalSubstance 2-amino-9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol go-plus.json http://purl.obolibrary.org/obo/CHEBI_45049 GO:0046862 biolink:CellularComponent chromoplast membrane Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope. go-plus.json http://purl.obolibrary.org/obo/GO_0046862 GO:0007210 biolink:BiologicalProcess serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. go-plus.json serotonin receptor signalling pathway http://purl.obolibrary.org/obo/GO_0007210 GO:0046861 biolink:CellularComponent glyoxysomal membrane The lipid bilayer surrounding a glyoxysome. go-plus.json glyoxysome membrane http://purl.obolibrary.org/obo/GO_0046861 CHEBI:84688 biolink:ChemicalSubstance Fe(III)-complexed hydroxamate siderophore go-plus.json http://purl.obolibrary.org/obo/CHEBI_84688 GO:0046860 biolink:CellularComponent glycosome membrane The lipid bilayer surrounding a glycosome. go-plus.json http://purl.obolibrary.org/obo/GO_0046860 CHEBI:59685 biolink:ChemicalSubstance edaxadiene go-plus.json http://purl.obolibrary.org/obo/CHEBI_59685 chebi_ph7_3 GO:0071829 biolink:BiologicalProcess plasma lipoprotein particle disassembly The disaggregation of a plasma lipoprotein particle into its constituent components. go-plus.json http://purl.obolibrary.org/obo/GO_0071829 GO:0071828 biolink:BiologicalProcess apolipoprotein E recycling The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle. go-plus.json APOE recycling http://purl.obolibrary.org/obo/GO_0071828 CHEBI:59683 biolink:ChemicalSubstance antipruritic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_59683 GO:0071827 biolink:BiologicalProcess plasma lipoprotein particle organization A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. go-plus.json plasma lipoprotein particle organisation http://purl.obolibrary.org/obo/GO_0071827 GO:0071826 biolink:BiologicalProcess ribonucleoprotein complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. go-plus.json protein-RNA complex subunit organization|RNA-protein complex subunit organization|ribonucleoprotein complex subunit organisation http://purl.obolibrary.org/obo/GO_0071826 GO:0046869 biolink:BiologicalProcess iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide. RESID:AA0331 go-plus.json iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato diiron disulphide http://purl.obolibrary.org/obo/GO_0046869 GO:0071825 biolink:BiologicalProcess protein-lipid complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex. go-plus.json protein-lipid complex subunit organisation http://purl.obolibrary.org/obo/GO_0071825 GO:0046868 biolink:CellularComponent mesosome An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins. Wikipedia:Mesosome go-plus.json http://purl.obolibrary.org/obo/GO_0046868 GO:0071824 biolink:BiologicalProcess protein-DNA complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex. go-plus.json protein-DNA complex subunit organisation|DNA-protein complex subunit organization http://purl.obolibrary.org/obo/GO_0071824 GO:0046867 biolink:BiologicalProcess carotenoid transport The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. go-plus.json http://purl.obolibrary.org/obo/GO_0046867 GO:0071823 biolink:BiologicalProcess protein-carbohydrate complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex. go-plus.json protein-carbohydrate complex subunit organisation http://purl.obolibrary.org/obo/GO_0071823 OBO:GOCHE_24127 biolink:OntologyClass substance with fungicide role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24127 3_STAR GO:0022855 biolink:MolecularActivity protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json glucose PTS transporter activity http://purl.obolibrary.org/obo/GO_0022855 GO:0071822 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071822 GO:0022854 biolink:MolecularActivity obsolete active large uncharged polar molecule transmembrane transporter activity OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction. go-plus.json active large uncharged polar molecule transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022854 GO:0071821 biolink:CellularComponent FANCM-MHF complex A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes. go-plus.json http://purl.obolibrary.org/obo/GO_0071821 GO:0022857 biolink:MolecularActivity transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. Reactome:R-HSA-5638209|Reactome:R-HSA-429036|Reactome:R-HSA-1236947|Reactome:R-HSA-6784436|Reactome:R-HSA-5671707|Reactome:R-HSA-6784434 go-plus.json substrate-specific transmembrane transporter activity|uptake transmembrane transporter activity|substrate-specific transporter activity|uptake permease activity http://purl.obolibrary.org/obo/GO_0022857 goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast GO:0071820 biolink:MolecularActivity N-box binding Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. go-plus.json N-box promoter binding|N box binding http://purl.obolibrary.org/obo/GO_0071820 GO:0022856 biolink:MolecularActivity protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json sorbitol PTS transporter activity http://purl.obolibrary.org/obo/GO_0022856 GO:0022859 biolink:MolecularActivity dephosphorylation-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0022859 GO:0022858 biolink:MolecularActivity alanine transmembrane transporter activity Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0022858 GO:1900939 biolink:BiologicalProcess negative regulation of (Z)-nonadeca-1,14-diene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process. go-plus.json down regulation of (Z)-nonadeca-1,14-diene metabolism|inhibition of (Z)-nonadeca-1,14-diene metabolic process|inhibition of (Z)-nonadeca-1,14-diene metabolism|down regulation of (Z)-nonadeca-1,14-diene metabolic process|negative regulation of (Z)-nonadeca-1,14-diene metabolism|down-regulation of (Z)-nonadeca-1,14-diene metabolism|downregulation of (Z)-nonadeca-1,14-diene metabolic process|downregulation of (Z)-nonadeca-1,14-diene metabolism|down-regulation of (Z)-nonadeca-1,14-diene metabolic process http://purl.obolibrary.org/obo/GO_1900939 CHEBI:59687 biolink:ChemicalSubstance halimane go-plus.json http://purl.obolibrary.org/obo/CHEBI_59687 chebi_ph7_3 CHEBI:59686 biolink:ChemicalSubstance halimane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59686 GO:1900947 biolink:BiologicalProcess regulation of isoprene biosynthetic process Any process that modulates the frequency, rate or extent of isoprene biosynthetic process. go-plus.json regulation of hemiterpene biosynthetic process|regulation of hemiterpene biosynthesis|regulation of 2-methyl-1,3-butadiene biosynthetic process|regulation of 2-methyl-1,3-butadiene biosynthesis http://purl.obolibrary.org/obo/GO_1900947 GO:1900946 biolink:BiologicalProcess positive regulation of isoprene metabolic process Any process that activates or increases the frequency, rate or extent of isoprene metabolic process. go-plus.json activation of hemiterpene metabolic process|up-regulation of isoprene metabolic process|positive regulation of hemiterpene metabolic process|activation of isoprene metabolic process|up regulation of isoprene metabolism|positive regulation of isoprene metabolism|activation of isoprene metabolism|up-regulation of hemiterpene metabolism|activation of hemiterpene metabolism|up-regulation of 2-methyl-1,3-butadiene metabolic process|activation of 2-methyl-1,3-butadiene metabolic process|up-regulation of 2-methyl-1,3-butadiene metabolism|up-regulation of hemiterpene metabolic process|up regulation of isoprene metabolic process|positive regulation of hemiterpene metabolism|up-regulation of isoprene metabolism|up regulation of hemiterpene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolic process|upregulation of 2-methyl-1,3-butadiene metabolism|up regulation of 2-methyl-1,3-butadiene metabolic process|upregulation of hemiterpene metabolic process|upregulation of isoprene metabolic process|upregulation of isoprene metabolism|upregulation of hemiterpene metabolism|up regulation of 2-methyl-1,3-butadiene metabolism|upregulation of 2-methyl-1,3-butadiene metabolic process|activation of 2-methyl-1,3-butadiene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolism|up regulation of hemiterpene metabolic process http://purl.obolibrary.org/obo/GO_1900946 GO:1900949 biolink:BiologicalProcess positive regulation of isoprene biosynthetic process Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process. go-plus.json up-regulation of hemiterpene biosynthesis|activation of isoprene biosynthetic process|up-regulation of hemiterpene biosynthetic process|activation of hemiterpene biosynthesis|activation of hemiterpene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthesis|positive regulation of hemiterpene biosynthesis|up-regulation of isoprene biosynthetic process|positive regulation of hemiterpene biosynthetic process|up regulation of hemiterpene biosynthesis|up regulation of hemiterpene biosynthetic process|upregulation of 2-methyl-1,3-butadiene biosynthesis|upregulation of 2-methyl-1,3-butadiene biosynthetic process|upregulation of isoprene biosynthetic process|upregulation of hemiterpene biosynthetic process|upregulation of hemiterpene biosynthesis|up regulation of 2-methyl-1,3-butadiene biosynthetic process|up regulation of 2-methyl-1,3-butadiene biosynthesis|positive regulation of 2-methyl-1,3-butadiene biosynthetic process|positive regulation of 2-methyl-1,3-butadiene biosynthesis|activation of 2-methyl-1,3-butadiene biosynthetic process|activation of 2-methyl-1,3-butadiene biosynthesis|up regulation of isoprene biosynthetic process http://purl.obolibrary.org/obo/GO_1900949 GO:1900948 biolink:BiologicalProcess negative regulation of isoprene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process. go-plus.json down-regulation of isoprene biosynthetic process|inhibition of 2-methyl-1,3-butadiene biosynthesis|inhibition of 2-methyl-1,3-butadiene biosynthetic process|negative regulation of hemiterpene biosynthesis|down-regulation of hemiterpene biosynthesis|negative regulation of hemiterpene biosynthetic process|down-regulation of hemiterpene biosynthetic process|inhibition of isoprene biosynthetic process|downregulation of hemiterpene biosynthetic process|downregulation of hemiterpene biosynthesis|down regulation of 2-methyl-1,3-butadiene biosynthetic process|down regulation of 2-methyl-1,3-butadiene biosynthesis|down regulation of hemiterpene biosynthetic process|down regulation of hemiterpene biosynthesis|inhibition of hemiterpene biosynthesis|downregulation of 2-methyl-1,3-butadiene biosynthetic process|downregulation of 2-methyl-1,3-butadiene biosynthesis|inhibition of hemiterpene biosynthetic process|down regulation of isoprene biosynthetic process|downregulation of isoprene biosynthetic process|negative regulation of 2-methyl-1,3-butadiene biosynthesis|negative regulation of 2-methyl-1,3-butadiene biosynthetic process|down-regulation of 2-methyl-1,3-butadiene biosynthesis|down-regulation of 2-methyl-1,3-butadiene biosynthetic process http://purl.obolibrary.org/obo/GO_1900948 GO:1900943 biolink:BiologicalProcess positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process. go-plus.json up-regulation of (Z)-nonadeca-1,14-diene synthesis|positive regulation of (Z)-nonadeca-1,14-diene biosynthesis|up-regulation of (Z)-nonadeca-1,14-diene formation|up regulation of (Z)-nonadeca-1,14-diene biosynthetic process|up regulation of (Z)-nonadeca-1,14-diene biosynthesis|upregulation of (Z)-nonadeca-1,14-diene anabolism|upregulation of (Z)-nonadeca-1,14-diene synthesis|upregulation of (Z)-nonadeca-1,14-diene formation|upregulation of (Z)-nonadeca-1,14-diene biosynthetic process|upregulation of (Z)-nonadeca-1,14-diene biosynthesis|up regulation of (Z)-nonadeca-1,14-diene anabolism|activation of (Z)-nonadeca-1,14-diene anabolism|positive regulation of (Z)-nonadeca-1,14-diene anabolism|up regulation of (Z)-nonadeca-1,14-diene synthesis|activation of (Z)-nonadeca-1,14-diene synthesis|positive regulation of (Z)-nonadeca-1,14-diene synthesis|up regulation of (Z)-nonadeca-1,14-diene formation|up-regulation of (Z)-nonadeca-1,14-diene biosynthesis|activation of (Z)-nonadeca-1,14-diene biosynthetic process|activation of (Z)-nonadeca-1,14-diene biosynthesis|up-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|activation of (Z)-nonadeca-1,14-diene formation|positive regulation of (Z)-nonadeca-1,14-diene formation|up-regulation of (Z)-nonadeca-1,14-diene anabolism http://purl.obolibrary.org/obo/GO_1900943 GO:0022840 biolink:MolecularActivity leak channel activity Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state. go-plus.json http://purl.obolibrary.org/obo/GO_0022840 GO:0007229 biolink:BiologicalProcess integrin-mediated signaling pathway A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json integrin-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0007229 GO:1900942 biolink:BiologicalProcess negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process. go-plus.json inhibition of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene biosynthetic process|downregulation of (Z)-nonadeca-1,14-diene biosynthesis|down regulation of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene biosynthetic process|down regulation of (Z)-nonadeca-1,14-diene biosynthesis|inhibition of (Z)-nonadeca-1,14-diene biosynthetic process|inhibition of (Z)-nonadeca-1,14-diene biosynthesis|downregulation of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene synthesis|down regulation of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene synthesis|downregulation of (Z)-nonadeca-1,14-diene formation|negative regulation of (Z)-nonadeca-1,14-diene anabolism|down-regulation of (Z)-nonadeca-1,14-diene anabolism|negative regulation of (Z)-nonadeca-1,14-diene synthesis|down-regulation of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene anabolism|negative regulation of (Z)-nonadeca-1,14-diene formation|down-regulation of (Z)-nonadeca-1,14-diene formation|negative regulation of (Z)-nonadeca-1,14-diene biosynthesis|down-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|down-regulation of (Z)-nonadeca-1,14-diene biosynthesis http://purl.obolibrary.org/obo/GO_1900942 GO:0007228 biolink:BiologicalProcess positive regulation of hh target transcription factor activity Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited. go-plus.json positive regulation of hedgehog target transcription factor|activation of hh target transcription factor http://purl.obolibrary.org/obo/GO_0007228 GO:1900945 biolink:BiologicalProcess negative regulation of isoprene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process. go-plus.json down-regulation of 2-methyl-1,3-butadiene metabolism|negative regulation of 2-methyl-1,3-butadiene metabolism|down-regulation of hemiterpene metabolic process|negative regulation of hemiterpene metabolic process|down-regulation of isoprene metabolic process|negative regulation of isoprene metabolism|down-regulation of isoprene metabolism|inhibition of 2-methyl-1,3-butadiene metabolism|down-regulation of hemiterpene metabolism|negative regulation of hemiterpene metabolism|inhibition of hemiterpene metabolic process|down-regulation of 2-methyl-1,3-butadiene metabolic process|negative regulation of 2-methyl-1,3-butadiene metabolic process|inhibition of isoprene metabolism|downregulation of isoprene metabolic process|downregulation of hemiterpene metabolism|down regulation of 2-methyl-1,3-butadiene metabolism|down regulation of isoprene metabolic process|downregulation of 2-methyl-1,3-butadiene metabolic process|inhibition of isoprene metabolic process|down regulation of hemiterpene metabolism|down regulation of hemiterpene metabolic process|downregulation of 2-methyl-1,3-butadiene metabolism|inhibition of hemiterpene metabolism|down regulation of isoprene metabolism|down regulation of 2-methyl-1,3-butadiene metabolic process|downregulation of hemiterpene metabolic process|inhibition of 2-methyl-1,3-butadiene metabolic process|downregulation of isoprene metabolism http://purl.obolibrary.org/obo/GO_1900945 GO:0022842 biolink:MolecularActivity narrow pore channel activity Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated. go-plus.json http://purl.obolibrary.org/obo/GO_0022842 SO:0001263 biolink:SequenceFeature ncRNA_gene A gene that encodes a non-coding RNA. go-plus.json non-coding RNA gene|ncRNA gene http://purl.obolibrary.org/obo/SO_0001263 Alliance_of_Genome_Resources GO:0007227 biolink:BiologicalProcess signal transduction downstream of smoothened The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway. go-plus.json http://purl.obolibrary.org/obo/GO_0007227 GO:1900944 biolink:BiologicalProcess regulation of isoprene metabolic process Any process that modulates the frequency, rate or extent of isoprene metabolic process. go-plus.json regulation of hemiterpene metabolism|regulation of 2-methyl-1,3-butadiene metabolism|regulation of 2-methyl-1,3-butadiene metabolic process|regulation of hemiterpene metabolic process|regulation of isoprene metabolism http://purl.obolibrary.org/obo/GO_1900944 GO:0022841 biolink:MolecularActivity potassium ion leak channel activity Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state. go-plus.json http://purl.obolibrary.org/obo/GO_0022841 GO:0007226 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007226 GO:0007225 biolink:BiologicalProcess patched ligand maturation The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups. go-plus.json hh protein processing|patched ligand processing|Hedgehog protein processing http://purl.obolibrary.org/obo/GO_0007225 CHEBI:21080 biolink:ChemicalSubstance ribose diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21080 GO:0046877 biolink:BiologicalProcess regulation of saliva secretion Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0046877 GO:0046876 biolink:MolecularActivity 3,4-didehydroretinal binding Binding to 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod). go-plus.json opsin|red-sensitive opsin|long-wave-sensitive opsin|short-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|violet-sensitive opsin|blue-sensitive opsin http://purl.obolibrary.org/obo/GO_0046876 GO:0007224 biolink:BiologicalProcess smoothened signaling pathway A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. Wikipedia:Hedgehog_signaling_pathway go-plus.json smoothened signalling pathway|hh signalling pathway|Sonic hedgehog signaling pathway|hh signaling pathway|Shh signaling pathway|hedgehog signaling pathway http://purl.obolibrary.org/obo/GO_0007224 GO:0046875 biolink:MolecularActivity ephrin receptor binding Binding to an ephrin receptor. go-plus.json GPI-linked ephrin|transmembrane ephrin|Eph receptor binding|ephrin http://purl.obolibrary.org/obo/GO_0046875 GO:1900941 biolink:BiologicalProcess regulation of (Z)-nonadeca-1,14-diene biosynthetic process Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process. go-plus.json regulation of (Z)-nonadeca-1,14-diene biosynthesis|regulation of (Z)-nonadeca-1,14-diene anabolism|regulation of (Z)-nonadeca-1,14-diene synthesis|regulation of (Z)-nonadeca-1,14-diene formation http://purl.obolibrary.org/obo/GO_1900941 GO:0007223 biolink:BiologicalProcess Wnt signaling pathway, calcium modulating pathway The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). go-plus.json non-canonical Wnt signaling pathway|Wnt receptor signaling pathway, calcium modulating pathway|Wnt-activated signaling pathway, calcium modulating pathway|frizzled-2 signaling pathway|frizzled-2 signalling pathway http://purl.obolibrary.org/obo/GO_0007223 GO:1900940 biolink:BiologicalProcess positive regulation of (Z)-nonadeca-1,14-diene metabolic process Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process. go-plus.json up regulation of (Z)-nonadeca-1,14-diene metabolic process|positive regulation of (Z)-nonadeca-1,14-diene metabolism|activation of (Z)-nonadeca-1,14-diene metabolic process|up regulation of (Z)-nonadeca-1,14-diene metabolism|upregulation of (Z)-nonadeca-1,14-diene metabolism|up-regulation of (Z)-nonadeca-1,14-diene metabolic process|up-regulation of (Z)-nonadeca-1,14-diene metabolism|upregulation of (Z)-nonadeca-1,14-diene metabolic process|activation of (Z)-nonadeca-1,14-diene metabolism http://purl.obolibrary.org/obo/GO_1900940 GO:0046874 biolink:BiologicalProcess quinolinate metabolic process The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. go-plus.json quinolinate metabolism http://purl.obolibrary.org/obo/GO_0046874 GO:0007222 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007222 GO:0007221 biolink:BiologicalProcess positive regulation of transcription of Notch receptor target The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain. go-plus.json N receptor target transcription factor activation|Notch receptor target transcription factor activation http://purl.obolibrary.org/obo/GO_0007221 GO:0046873 biolink:MolecularActivity metal ion transmembrane transporter activity Enables the transfer of metal ions from one side of a membrane to the other. go-plus.json high affinity metal ion uptake transporter activity|heavy metal-exporting ATPase activity|heavy metal ion transporter activity|low affinity metal ion uptake transporter activity|heavy metal ion porter activity|heavy metal ion:hydrogen symporter activity http://purl.obolibrary.org/obo/GO_0046873 GO:0046872 biolink:MolecularActivity metal ion binding Binding to a metal ion. go-plus.json heavy metal binding|metal binding http://purl.obolibrary.org/obo/GO_0046872 goslim_flybase_ribbon|goslim_agr|goslim_drosophila|goslim_metagenomics GO:0007220 biolink:BiologicalProcess Notch receptor processing The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor. go-plus.json N receptor processing http://purl.obolibrary.org/obo/GO_0007220 GO:0046871 biolink:MolecularActivity N-acetylgalactosamine binding Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine. go-plus.json N-acetylgalactosamine lectin http://purl.obolibrary.org/obo/GO_0046871 GO:0071809 biolink:BiologicalProcess regulation of fever generation by regulation of prostaglandin biosynthesis Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. go-plus.json http://purl.obolibrary.org/obo/GO_0071809 GO:0046870 biolink:MolecularActivity cadmium ion binding Binding to a cadmium ion (Cd). go-plus.json Cd ion binding|cadmium binding|copper/cadmium binding http://purl.obolibrary.org/obo/GO_0046870 GO:0071819 biolink:CellularComponent DUBm complex A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p. go-plus.json deubiquitinating module|SAGA DUBm complex|deubiquitination module http://purl.obolibrary.org/obo/GO_0071819 GO:0071818 biolink:CellularComponent BAT3 complex A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A. go-plus.json BAG6-UBL4A-TRC35 complex|BAT3-TRC35-UBL4A complex|Bag6 complex http://purl.obolibrary.org/obo/GO_0071818 GO:0071817 biolink:CellularComponent MMXD complex A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation. go-plus.json MMS19-MIP18-XPD complex http://purl.obolibrary.org/obo/GO_0071817 GO:0071816 biolink:BiologicalProcess tail-anchored membrane protein insertion into ER membrane A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region. go-plus.json protein insertion of tail-anchored membrane proteins into ER membrane|type II transmembrane protein insertion into ER membrane|tail-anchored membrane protein insertion into endoplasmic reticulum membrane http://purl.obolibrary.org/obo/GO_0071816 GO:0071815 biolink:MolecularActivity intermediate-density lipoprotein particle binding Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. go-plus.json IDL binding|intermediate-density lipoprotein binding http://purl.obolibrary.org/obo/GO_0071815 GO:0071814 biolink:MolecularActivity protein-lipid complex binding Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules. go-plus.json http://purl.obolibrary.org/obo/GO_0071814 GO:0071813 biolink:MolecularActivity lipoprotein particle binding Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. go-plus.json plasma lipoprotein binding|lipoprotein binding|plasma lipoprotein particle binding http://purl.obolibrary.org/obo/GO_0071813 GO:0046879 biolink:BiologicalProcess hormone secretion The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. go-plus.json http://purl.obolibrary.org/obo/GO_0046879 GO:0046878 biolink:BiologicalProcess positive regulation of saliva secretion Any process that activates or increases the frequency, rate or extent of the regulated release of saliva. go-plus.json upregulation of saliva secretion|stimulation of saliva secretion|up-regulation of saliva secretion|activation of saliva secretion|up regulation of saliva secretion http://purl.obolibrary.org/obo/GO_0046878 GO:0071812 biolink:BiologicalProcess positive regulation of fever generation by positive regulation of prostaglandin secretion Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0071812 GO:0071811 biolink:BiologicalProcess positive regulation of fever generation by positive regulation of prostaglandin biosynthesis Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. go-plus.json http://purl.obolibrary.org/obo/GO_0071811 GO:0022844 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022844 GO:0071810 biolink:BiologicalProcess regulation of fever generation by regulation of prostaglandin secretion Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0071810 GO:0022843 biolink:MolecularActivity voltage-gated cation channel activity Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Reactome:R-HSA-6788999|Reactome:R-HSA-2534378 go-plus.json http://purl.obolibrary.org/obo/GO_0022843 GO:0022848 biolink:MolecularActivity acetylcholine-gated cation-selective channel activity Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine. go-plus.json nicotinergic acetylcholine receptor activity|ionotropic acetylcholine receptor activity|acetylcholine-activated cation-selective channel activity|nicotinic acetylcholine-activated cation-selective channel activity|acetylcholine-gated cation channel activity|nAChR http://purl.obolibrary.org/obo/GO_0022848 GO:0022849 biolink:MolecularActivity glutamate-gated calcium ion channel activity Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0022849 GO:1900958 biolink:BiologicalProcess positive regulation of 17-methylnonadec-1-ene biosynthetic process Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process. go-plus.json up-regulation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene synthesis|up regulation of 17-methylnonadec-1-ene synthesis|positive regulation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene formation|upregulation of 17-methylnonadec-1-ene biosynthesis|upregulation of 17-methylnonadec-1-ene biosynthetic process|upregulation of 17-methylnonadec-1-ene anabolism|upregulation of 17-methylnonadec-1-ene synthesis|upregulation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene biosynthesis|up regulation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene synthesis|activation of 17-methylnonadec-1-ene anabolism|activation of 17-methylnonadec-1-ene biosynthesis|up-regulation of 17-methylnonadec-1-ene formation|activation of 17-methylnonadec-1-ene synthesis|positive regulation of 17-methylnonadec-1-ene anabolism http://purl.obolibrary.org/obo/GO_1900958 GO:0046880 biolink:BiologicalProcess regulation of follicle-stimulating hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone. go-plus.json regulation of FSH secretion|regulation of follicle stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0046880 GO:1900957 biolink:BiologicalProcess negative regulation of 17-methylnonadec-1-ene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process. go-plus.json negative regulation of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene formation|downregulation of 17-methylnonadec-1-ene anabolism|inhibition of 17-methylnonadec-1-ene biosynthesis|down regulation of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene synthesis|downregulation of 17-methylnonadec-1-ene formation|down regulation of 17-methylnonadec-1-ene biosynthetic process|down regulation of 17-methylnonadec-1-ene biosynthesis|down regulation of 17-methylnonadec-1-ene synthesis|down regulation of 17-methylnonadec-1-ene formation|inhibition of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene biosynthesis|downregulation of 17-methylnonadec-1-ene biosynthetic process|inhibition of 17-methylnonadec-1-ene synthesis|inhibition of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene biosynthetic process|negative regulation of 17-methylnonadec-1-ene biosynthesis|down-regulation of 17-methylnonadec-1-ene biosynthesis|negative regulation of 17-methylnonadec-1-ene anabolism|down-regulation of 17-methylnonadec-1-ene anabolism|negative regulation of 17-methylnonadec-1-ene synthesis|down-regulation of 17-methylnonadec-1-ene synthesis|inhibition of 17-methylnonadec-1-ene biosynthetic process http://purl.obolibrary.org/obo/GO_1900957 CHEBI:45021 biolink:ChemicalSubstance palmitoyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_45021 chebi_ph7_3 CHEBI:21054 biolink:ChemicalSubstance mannonic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21054 GO:1900959 biolink:BiologicalProcess regulation of 17-methylnonadec-1-ene metabolic process Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process. go-plus.json regulation of 17-methylnonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900959 GO:1900954 biolink:BiologicalProcess negative regulation of 18-methylnonadec-1-ene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process. go-plus.json inhibition of 18-methylnonadec-1-ene metabolism|down-regulation of 18-methylnonadec-1-ene metabolic process|down regulation of 18-methylnonadec-1-ene metabolism|downregulation of 18-methylnonadec-1-ene metabolism|downregulation of 18-methylnonadec-1-ene metabolic process|down regulation of 18-methylnonadec-1-ene metabolic process|down-regulation of 18-methylnonadec-1-ene metabolism|negative regulation of 18-methylnonadec-1-ene metabolism|inhibition of 18-methylnonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900954 GO:1900953 biolink:BiologicalProcess regulation of 18-methylnonadec-1-ene metabolic process Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process. go-plus.json regulation of 18-methylnonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900953 GO:1900956 biolink:BiologicalProcess regulation of 17-methylnonadec-1-ene biosynthetic process Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process. go-plus.json regulation of 17-methylnonadec-1-ene anabolism|regulation of 17-methylnonadec-1-ene synthesis|regulation of 17-methylnonadec-1-ene formation|regulation of 17-methylnonadec-1-ene biosynthesis http://purl.obolibrary.org/obo/GO_1900956 GO:0022831 biolink:MolecularActivity narrow pore, gated channel activity Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus. Wikipedia:Ion_channels go-plus.json ion channels http://purl.obolibrary.org/obo/GO_0022831 GO:1900955 biolink:BiologicalProcess positive regulation of 18-methylnonadec-1-ene metabolic process Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process. go-plus.json up-regulation of 18-methylnonadec-1-ene metabolism|up-regulation of 18-methylnonadec-1-ene metabolic process|activation of 18-methylnonadec-1-ene metabolic process|upregulation of 18-methylnonadec-1-ene metabolism|up regulation of 18-methylnonadec-1-ene metabolic process|up regulation of 18-methylnonadec-1-ene metabolism|positive regulation of 18-methylnonadec-1-ene metabolism|activation of 18-methylnonadec-1-ene metabolism|upregulation of 18-methylnonadec-1-ene metabolic process http://purl.obolibrary.org/obo/GO_1900955 GO:0046888 biolink:BiologicalProcess negative regulation of hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. go-plus.json down regulation of hormone secretion|downregulation of hormone secretion|down-regulation of hormone secretion|inhibition of hormone secretion http://purl.obolibrary.org/obo/GO_0046888 GO:1900950 biolink:BiologicalProcess regulation of 18-methylnonadec-1-ene biosynthetic process Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process. go-plus.json regulation of 18-methylnonadec-1-ene anabolism|regulation of 18-methylnonadec-1-ene synthesis|regulation of 18-methylnonadec-1-ene formation|regulation of 18-methylnonadec-1-ene biosynthesis http://purl.obolibrary.org/obo/GO_1900950 GO:0046887 biolink:BiologicalProcess positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. go-plus.json up regulation of hormone secretion|activation of hormone secretion|stimulation of hormone secretion|up-regulation of hormone secretion|upregulation of hormone secretion http://purl.obolibrary.org/obo/GO_0046887 GO:1900952 biolink:BiologicalProcess positive regulation of 18-methylnonadec-1-ene biosynthetic process Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process. go-plus.json up regulation of 18-methylnonadec-1-ene synthesis|positive regulation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene formation|upregulation of 18-methylnonadec-1-ene biosynthetic process|upregulation of 18-methylnonadec-1-ene anabolism|upregulation of 18-methylnonadec-1-ene biosynthesis|upregulation of 18-methylnonadec-1-ene synthesis|upregulation of 18-methylnonadec-1-ene formation|up-regulation of 18-methylnonadec-1-ene anabolism|up regulation of 18-methylnonadec-1-ene biosynthesis|up regulation of 18-methylnonadec-1-ene biosynthetic process|positive regulation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene synthesis|activation of 18-methylnonadec-1-ene anabolism|up-regulation of 18-methylnonadec-1-ene formation|activation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene synthesis|positive regulation of 18-methylnonadec-1-ene anabolism|activation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene anabolism|up-regulation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene biosynthesis|positive regulation of 18-methylnonadec-1-ene synthesis http://purl.obolibrary.org/obo/GO_1900952 GO:0046886 biolink:BiologicalProcess positive regulation of hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. go-plus.json positive regulation of hormone biosynthesis|positive regulation of hormone anabolism|up regulation of hormone biosynthetic process|positive regulation of hormone synthesis|positive regulation of hormone formation|upregulation of hormone biosynthetic process|stimulation of hormone biosynthetic process|up-regulation of hormone biosynthetic process|activation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0046886 GO:1900951 biolink:BiologicalProcess negative regulation of 18-methylnonadec-1-ene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process. go-plus.json downregulation of 18-methylnonadec-1-ene anabolism|inhibition of 18-methylnonadec-1-ene biosynthesis|down regulation of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene synthesis|downregulation of 18-methylnonadec-1-ene formation|down regulation of 18-methylnonadec-1-ene synthesis|down regulation of 18-methylnonadec-1-ene biosynthesis|down regulation of 18-methylnonadec-1-ene biosynthetic process|down regulation of 18-methylnonadec-1-ene formation|inhibition of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene biosynthetic process|downregulation of 18-methylnonadec-1-ene biosynthesis|inhibition of 18-methylnonadec-1-ene synthesis|inhibition of 18-methylnonadec-1-ene formation|down-regulation of 18-methylnonadec-1-ene biosynthetic process|down-regulation of 18-methylnonadec-1-ene anabolism|negative regulation of 18-methylnonadec-1-ene anabolism|down-regulation of 18-methylnonadec-1-ene biosynthesis|negative regulation of 18-methylnonadec-1-ene biosynthesis|down-regulation of 18-methylnonadec-1-ene synthesis|negative regulation of 18-methylnonadec-1-ene synthesis|inhibition of 18-methylnonadec-1-ene biosynthetic process|negative regulation of 18-methylnonadec-1-ene formation|down-regulation of 18-methylnonadec-1-ene formation http://purl.obolibrary.org/obo/GO_1900951 GO:0046885 biolink:BiologicalProcess regulation of hormone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. go-plus.json regulation of hormone anabolism|regulation of hormone synthesis|regulation of hormone formation|regulation of hormone biosynthesis http://purl.obolibrary.org/obo/GO_0046885 GO:0046884 biolink:BiologicalProcess follicle-stimulating hormone secretion The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. go-plus.json follitropin secretion|FSH secretion|follicle stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0046884 GO:0046883 biolink:BiologicalProcess regulation of hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0046883 GO:0046882 biolink:BiologicalProcess negative regulation of follicle-stimulating hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone. go-plus.json down-regulation of follicle-stimulating hormone secretion|downregulation of follicle-stimulating hormone secretion|down regulation of follicle-stimulating hormone secretion|inhibition of follicle-stimulating hormone secretion|negative regulation of follicle stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0046882 GO:0046881 biolink:BiologicalProcess positive regulation of follicle-stimulating hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone. go-plus.json stimulation of follicle-stimulating hormone secretion|positive regulation of follicle stimulating hormone secretion|activation of follicle-stimulating hormone secretion|up-regulation of follicle-stimulating hormone secretion|up regulation of follicle-stimulating hormone secretion|upregulation of follicle-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0046881 CHEBI:35695 biolink:ChemicalSubstance dicarboxylic acid monoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35695 UBERON:2000315 biolink:AnatomicalEntity asteriscus go-plus.json lagenar otolith|lagenolith http://purl.obolibrary.org/obo/UBERON_2000315 GO:0071849 biolink:BiologicalProcess obsolete G1 cell cycle arrest in response to nitrogen starvation OBSOLETE. The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen. go-plus.json http://purl.obolibrary.org/obo/GO_0071849 CHEBI:35697 biolink:ChemicalSubstance trans-cinnamic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35697 GO:0071848 biolink:BiologicalProcess positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade. go-plus.json positive regulation of ERK1 and ERK2 cascade via RANKL-mediated signaling|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalling http://purl.obolibrary.org/obo/GO_0071848 GO:0071847 biolink:BiologicalProcess TNFSF11-mediated signaling pathway A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json RANKL-mediated signaling pathway|TNFSF11-mediated signalling pathway|tumor necrosis factor superfamily member 11-mediated signaling pathway|receptor activator of nuclear factor kappa-B ligand signaling pathway|TNF-related activation-induced cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0071847 GO:0071846 biolink:BiologicalProcess actin filament debranching An actin filament severing process that results in the removal of actin filament branches specifically at the branch points. go-plus.json http://purl.obolibrary.org/obo/GO_0071846 GO:0046889 biolink:BiologicalProcess positive regulation of lipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. go-plus.json positive regulation of lipogenesis|positive regulation of lipid synthesis|positive regulation of lipid formation|stimulation of lipid biosynthetic process|up-regulation of lipid biosynthetic process|activation of lipid biosynthetic process|positive regulation of lipid biosynthesis|up regulation of lipid biosynthetic process|positive regulation of lipid anabolism|upregulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0046889 GO:0071845 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071845 GO:0022833 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022833 GO:0071844 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071844 CHEBI:69080 biolink:ChemicalSubstance methyl linoleate go-plus.json http://purl.obolibrary.org/obo/CHEBI_69080 chebi_ph7_3 GO:0022832 biolink:MolecularActivity voltage-gated channel activity Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. go-plus.json http://purl.obolibrary.org/obo/GO_0022832 GO:0071843 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071843 GO:0022835 biolink:MolecularActivity transmitter-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. go-plus.json neurotransmitter-gated channel activity|extracellular substance gated channel activity http://purl.obolibrary.org/obo/GO_0022835 CHEBI:35690 biolink:ChemicalSubstance cyclobutane-1,1-dicarboxylate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35690 chebi_ph7_3 GO:0071842 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071842 GO:0022834 biolink:MolecularActivity ligand-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0022834 GO:0071841 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071841 CHEBI:69081 biolink:ChemicalSubstance 1-monopalmitoylglycerol go-plus.json http://purl.obolibrary.org/obo/CHEBI_69081 chebi_ph7_3 GO:0071840 biolink:BiologicalProcess cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. go-plus.json cellular component organisation or biogenesis|cellular component organisation or biogenesis at cellular level|cellular component organization or biogenesis at cellular level http://purl.obolibrary.org/obo/GO_0071840 goslim_metagenomics|goslim_flybase_ribbon CHEBI:35692 biolink:ChemicalSubstance dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35692 GO:0022836 biolink:MolecularActivity gated channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0022836 CHEBI:35691 biolink:ChemicalSubstance cyclobutane-1,1-dicarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35691 GO:0022839 biolink:MolecularActivity ion gated channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0022839 CHEBI:35694 biolink:ChemicalSubstance cyclobutane-1,1-dicarboxylate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_35694 GO:0022838 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022838 CHEBI:35693 biolink:ChemicalSubstance dicarboxylic acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35693 GO:1900969 biolink:BiologicalProcess negative regulation of sarcinapterin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process. go-plus.json down-regulation of sarcinapterin metabolic process|negative regulation of sarcinapterin metabolism|down-regulation of sarcinapterin metabolism|inhibition of sarcinapterin metabolic process|downregulation of sarcinapterin metabolism|down regulation of sarcinapterin metabolism|down regulation of sarcinapterin metabolic process|downregulation of sarcinapterin metabolic process|inhibition of sarcinapterin metabolism http://purl.obolibrary.org/obo/GO_1900969 GO:0046891 biolink:BiologicalProcess peptidyl-cysteine S-carbamoylation The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine. RESID:AA0332 go-plus.json http://purl.obolibrary.org/obo/GO_0046891 GO:0046890 biolink:BiologicalProcess regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. go-plus.json regulation of lipid anabolism|regulation of lipogenesis|regulation of lipid biosynthesis|regulation of lipid synthesis|regulation of lipid formation http://purl.obolibrary.org/obo/GO_0046890 GO:1900968 biolink:BiologicalProcess regulation of sarcinapterin metabolic process Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process. go-plus.json regulation of sarcinapterin metabolism http://purl.obolibrary.org/obo/GO_1900968 GO:0007209 biolink:BiologicalProcess phospholipase C-activating tachykinin receptor signaling pathway The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json activation of phospholipase C activity by tachykinin receptor signaling pathway|activation of phospholipase C activity by tachykinin receptor signalling pathway|tachykinin receptor, phospholipase C activating pathway http://purl.obolibrary.org/obo/GO_0007209 GO:0007208 biolink:BiologicalProcess phospholipase C-activating serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json activation of phospholipase C activity by serotonin receptor signalling pathway|serotonin receptor, phospholipase C activating pathway|activation of phospholipase C activity by serotonin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007208 GO:0007207 biolink:BiologicalProcess phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json muscarinic acetylcholine receptor, phospholipase C activating pathway|activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway|activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway|phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway|muscarinic receptor signaling pathway via activation of PLC|activation of phospholipase C activity by muscarinic acetylcholine receptor signalling pathway http://purl.obolibrary.org/obo/GO_0007207 GO:1900965 biolink:BiologicalProcess regulation of methanophenazine metabolic process Any process that modulates the frequency, rate or extent of methanophenazine metabolic process. go-plus.json regulation of methanophenazine metabolism http://purl.obolibrary.org/obo/GO_1900965 GO:1900964 biolink:BiologicalProcess positive regulation of methanophenazine biosynthetic process Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process. go-plus.json up-regulation of methanophenazine biosynthesis|up-regulation of methanophenazine biosynthetic process|upregulation of methanophenazine anabolism|upregulation of methanophenazine synthesis|upregulation of methanophenazine formation|upregulation of methanophenazine biosynthesis|upregulation of methanophenazine biosynthetic process|up-regulation of methanophenazine anabolism|up-regulation of methanophenazine synthesis|activation of methanophenazine anabolism|up-regulation of methanophenazine formation|up regulation of methanophenazine biosynthesis|up regulation of methanophenazine biosynthetic process|activation of methanophenazine synthesis|positive regulation of methanophenazine anabolism|activation of methanophenazine biosynthetic process|positive regulation of methanophenazine biosynthesis|activation of methanophenazine formation|up regulation of methanophenazine anabolism|positive regulation of methanophenazine synthesis|activation of methanophenazine biosynthesis|up regulation of methanophenazine synthesis|positive regulation of methanophenazine formation|up regulation of methanophenazine formation http://purl.obolibrary.org/obo/GO_1900964 GO:0007206 biolink:BiologicalProcess phospholipase C-activating G protein-coupled glutamate receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json phospholipase C-activating G-protein coupled glutamate receptor signaling pathway|activation of phospholipase C activity by metabotropic glutamate receptor signalling pathway|activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor, phospholipase C activating pathway|activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007206 GO:1900967 biolink:BiologicalProcess positive regulation of methanophenazine metabolic process Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process. go-plus.json activation of methanophenazine metabolism|up-regulation of methanophenazine metabolic process|activation of methanophenazine metabolic process|up-regulation of methanophenazine metabolism|up regulation of methanophenazine metabolic process|upregulation of methanophenazine metabolism|upregulation of methanophenazine metabolic process|up regulation of methanophenazine metabolism|positive regulation of methanophenazine metabolism http://purl.obolibrary.org/obo/GO_1900967 GO:0007205 biolink:BiologicalProcess protein kinase C-activating G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG). go-plus.json activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway|activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007205 GO:0022820 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022820 GO:0007204 biolink:BiologicalProcess positive regulation of cytosolic calcium ion concentration Any process that increases the concentration of calcium ions in the cytosol. go-plus.json cytoplasmic calcium ion concentration elevation|elevation of cytoplasmic calcium ion concentration|cytosolic calcium ion concentration elevation|elevation of cytosolic calcium ion concentration|elevation of calcium ion concentration in cytoplasm|elevation of calcium ion concentration in cytosol http://purl.obolibrary.org/obo/GO_0007204 GO:1900966 biolink:BiologicalProcess negative regulation of methanophenazine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process. go-plus.json down-regulation of methanophenazine metabolic process|inhibition of methanophenazine metabolism|downregulation of methanophenazine metabolic process|down regulation of methanophenazine metabolism|down regulation of methanophenazine metabolic process|downregulation of methanophenazine metabolism|inhibition of methanophenazine metabolic process|down-regulation of methanophenazine metabolism|negative regulation of methanophenazine metabolism http://purl.obolibrary.org/obo/GO_1900966 GO:1900961 biolink:BiologicalProcess positive regulation of 17-methylnonadec-1-ene metabolic process Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process. go-plus.json up regulation of 17-methylnonadec-1-ene metabolic process|up regulation of 17-methylnonadec-1-ene metabolism|positive regulation of 17-methylnonadec-1-ene metabolism|activation of 17-methylnonadec-1-ene metabolism|upregulation of 17-methylnonadec-1-ene metabolic process|up-regulation of 17-methylnonadec-1-ene metabolism|up-regulation of 17-methylnonadec-1-ene metabolic process|activation of 17-methylnonadec-1-ene metabolic process|upregulation of 17-methylnonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900961 GO:0007203 biolink:BiologicalProcess obsolete phosphatidylinositol-4,5-bisphosphate hydrolysis OBSOLETE. (Was not defined before being made obsolete). go-plus.json phosphatidylinositol-4,5-bisphosphate hydrolysis http://purl.obolibrary.org/obo/GO_0007203 GO:0046899 biolink:MolecularActivity nucleoside triphosphate adenylate kinase activity Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP. RHEA:13749|Reactome:R-HSA-1008248|EC:2.7.4.10|MetaCyc:2.7.4.10-RXN go-plus.json guanosine triphosphate-adenylate kinase|nucleoside triphosphate-adenosine monophosphate transphosphorylase activity|isozyme 3 of adenylate kinase activity|GTP:AMP phosphotransferase|nucleoside-triphosphate-adenylate kinase activity|nucleoside-triphosphate:AMP phosphotransferase activity http://purl.obolibrary.org/obo/GO_0046899 GO:1900960 biolink:BiologicalProcess negative regulation of 17-methylnonadec-1-ene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process. go-plus.json downregulation of 17-methylnonadec-1-ene metabolic process|negative regulation of 17-methylnonadec-1-ene metabolism|down-regulation of 17-methylnonadec-1-ene metabolism|down regulation of 17-methylnonadec-1-ene metabolic process|inhibition of 17-methylnonadec-1-ene metabolic process|inhibition of 17-methylnonadec-1-ene metabolism|down regulation of 17-methylnonadec-1-ene metabolism|down-regulation of 17-methylnonadec-1-ene metabolic process|downregulation of 17-methylnonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900960 GO:0046898 biolink:BiologicalProcess response to cycloheximide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes. go-plus.json response to actidione http://purl.obolibrary.org/obo/GO_0046898 GO:0007202 biolink:BiologicalProcess activation of phospholipase C activity The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand. go-plus.json phospholipase C activation http://purl.obolibrary.org/obo/GO_0007202 GO:1900963 biolink:BiologicalProcess negative regulation of methanophenazine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process. go-plus.json inhibition of methanophenazine biosynthetic process|downregulation of methanophenazine formation|down regulation of methanophenazine synthesis|inhibition of methanophenazine anabolism|down regulation of methanophenazine formation|inhibition of methanophenazine biosynthesis|inhibition of methanophenazine synthesis|down regulation of methanophenazine biosynthetic process|inhibition of methanophenazine formation|down regulation of methanophenazine biosynthesis|downregulation of methanophenazine biosynthesis|downregulation of methanophenazine biosynthetic process|down-regulation of methanophenazine anabolism|negative regulation of methanophenazine anabolism|down-regulation of methanophenazine synthesis|negative regulation of methanophenazine synthesis|down-regulation of methanophenazine formation|negative regulation of methanophenazine formation|down-regulation of methanophenazine biosynthesis|down-regulation of methanophenazine biosynthetic process|negative regulation of methanophenazine biosynthesis|downregulation of methanophenazine anabolism|down regulation of methanophenazine anabolism|downregulation of methanophenazine synthesis http://purl.obolibrary.org/obo/GO_1900963 GO:0046897 biolink:BiologicalProcess N-terminal peptidyl-tyrosine methylation The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine. RESID:AA0338 go-plus.json http://purl.obolibrary.org/obo/GO_0046897 GO:0007201 biolink:BiologicalProcess obsolete G-protein dissociation OBSOLETE. (Was not defined before being made obsolete). go-plus.json G-protein dissociation http://purl.obolibrary.org/obo/GO_0007201 CHEBI:21060 biolink:ChemicalSubstance mannose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21060 GO:1900962 biolink:BiologicalProcess regulation of methanophenazine biosynthetic process Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process. go-plus.json regulation of methanophenazine synthesis|regulation of methanophenazine formation|regulation of methanophenazine biosynthesis|regulation of methanophenazine anabolism http://purl.obolibrary.org/obo/GO_1900962 GO:0007200 biolink:BiologicalProcess phospholipase C-activating G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json G-protein coupled receptor signaling pathway coupled to IP3 second messenger|G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|phospholipase C-activating dopamine receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|PLC-activating GPCR signaling pathway http://purl.obolibrary.org/obo/GO_0007200 GO:0046896 biolink:BiologicalProcess N-terminal peptidyl-leucine methylation The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine. RESID:AA0337 go-plus.json http://purl.obolibrary.org/obo/GO_0046896 GO:0046895 biolink:BiologicalProcess N-terminal peptidyl-isoleucine methylation The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine. RESID:AA0336 go-plus.json http://purl.obolibrary.org/obo/GO_0046895 GO:0046894 biolink:BiologicalProcess obsolete enzyme active site formation via S-amidino-L-cysteine OBSOLETE. Active site formation via the transient amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine. go-plus.json http://purl.obolibrary.org/obo/GO_0046894 GO:0046893 biolink:BiologicalProcess iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase. RESID:AA0334 go-plus.json http://purl.obolibrary.org/obo/GO_0046893 CHEBI:45013 biolink:ChemicalSubstance 2-phospho-L-lactic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_45013 GO:0046892 biolink:BiologicalProcess peptidyl-S-carbamoyl-L-cysteine dehydration The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine. RESID:AA0333 go-plus.json formation of peptidyl-serine thiocyanate ester|formation of peptidyl-S-cyanocysteine http://purl.obolibrary.org/obo/GO_0046892 GO:0140096 biolink:MolecularActivity catalytic activity, acting on a protein Catalytic activity that acts to modify a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140096 GO:0022829 biolink:MolecularActivity wide pore channel activity Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts. go-plus.json non-gated, wide pore channel activity|gap junction activity http://purl.obolibrary.org/obo/GO_0022829 CHEBI:59651 biolink:ChemicalSubstance arseno-mycothiol go-plus.json http://purl.obolibrary.org/obo/CHEBI_59651 GO:0071839 biolink:BiologicalProcess apoptotic process in bone marrow cell The apoptotic process in cells in the bone marrow. go-plus.json programmed cell death, bone marrow cells|killing of bone marrow cells|apoptotic process in bone marrow cell|programmed cell death of bone marrow cells by apoptosis|apoptosis in bone marrow|bone marrow cell apoptosis|bone marrow cell programmed cell death by apoptosis http://purl.obolibrary.org/obo/GO_0071839 GO:0140098 biolink:MolecularActivity catalytic activity, acting on RNA Catalytic activity that acts to modify RNA, driven by ATP hydrolysis. go-plus.json http://purl.obolibrary.org/obo/GO_0140098 CHEBI:59650 biolink:ChemicalSubstance amino fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59650 GO:0071838 biolink:BiologicalProcess cell proliferation in bone marrow The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow. go-plus.json bone marrow cell proliferation http://purl.obolibrary.org/obo/GO_0071838 GO:0140097 biolink:MolecularActivity catalytic activity, acting on DNA Catalytic activity that acts to modify DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140097 GO:0071837 biolink:MolecularActivity HMG box domain binding Binding to an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. go-plus.json http://purl.obolibrary.org/obo/GO_0071837 GO:0071836 biolink:BiologicalProcess nectar secretion The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins. go-plus.json nectar production http://purl.obolibrary.org/obo/GO_0071836 GO:0071835 biolink:BiologicalProcess mating pheromone secretion involved in regulation of conjugation The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms. go-plus.json mating-type pheromone secretion involved in conjugation http://purl.obolibrary.org/obo/GO_0071835 GO:0071834 biolink:BiologicalProcess mating pheromone secretion The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction. go-plus.json mating-type pheromone secretion http://purl.obolibrary.org/obo/GO_0071834 GO:0071833 biolink:BiologicalProcess peptide pheromone export involved in positive regulation of conjugation with cellular fusion The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types. go-plus.json http://purl.obolibrary.org/obo/GO_0071833 GO:0071832 biolink:BiologicalProcess peptide pheromone export involved in regulation of conjugation The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms. go-plus.json http://purl.obolibrary.org/obo/GO_0071832 GO:0022821 biolink:MolecularActivity potassium ion antiporter activity Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. go-plus.json http://purl.obolibrary.org/obo/GO_0022821 GO:0071831 biolink:BiologicalProcess intermediate-density lipoprotein particle clearance The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json IDL clearance http://purl.obolibrary.org/obo/GO_0071831 GO:0140090 biolink:MolecularActivity membrane curvature sensor activity Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0140090 GO:0022824 biolink:MolecularActivity transmitter-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. go-plus.json ionotropic neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0022824 GO:0071830 biolink:BiologicalProcess triglyceride-rich lipoprotein particle clearance The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0071830 GO:0140092 biolink:CellularComponent bBAF complex A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180. go-plus.json brain-specific BAF complex|brain-specific SWI/SNF complex http://purl.obolibrary.org/obo/GO_0140092 GO:0140091 biolink:CellularComponent mBAF complex A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof. go-plus.json muscle-type BAF complex|muscle-type SWI/SNF complex|muscle-specific BAF complex|muscle-specific SWI/SNF complex http://purl.obolibrary.org/obo/GO_0140091 GO:0022825 biolink:MolecularActivity obsolete copper-exporting ATPase activity OBSOLETE. (Was not defined before being made obsolete). go-plus.json copper-exporting ATPase activity http://purl.obolibrary.org/obo/GO_0022825 CHEBI:59655 biolink:ChemicalSubstance arseno-mycothiol(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59655 chebi_ph7_3 GO:0022828 biolink:MolecularActivity phosphorylation-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts. go-plus.json http://purl.obolibrary.org/obo/GO_0022828 GO:0140093 biolink:CellularComponent esBAF complex An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C. go-plus.json embryonic stem cell-specific BAF complex|embryonic stem cell-specific SWI/SNF complex http://purl.obolibrary.org/obo/GO_0140093 CHEBI:59653 biolink:ChemicalSubstance arseno-mycothiol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59653 GO:1900979 biolink:BiologicalProcess positive regulation of tatiopterin metabolic process Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process. go-plus.json activation of tatiopterin metabolism|up-regulation of tatiopterin metabolic process|positive regulation of tatiopterin metabolism|up regulation of tatiopterin metabolism|upregulation of tatiopterin metabolic process|upregulation of tatiopterin metabolism|up regulation of tatiopterin metabolic process|activation of tatiopterin metabolic process|up-regulation of tatiopterin metabolism http://purl.obolibrary.org/obo/GO_1900979 GO:1900976 biolink:BiologicalProcess positive regulation of tatiopterin biosynthetic process Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process. go-plus.json upregulation of tatiopterin formation|positive regulation of tatiopterin biosynthesis|up regulation of tatiopterin anabolism|positive regulation of tatiopterin anabolism|up regulation of tatiopterin biosynthesis|up regulation of tatiopterin biosynthetic process|up regulation of tatiopterin synthesis|positive regulation of tatiopterin synthesis|activation of tatiopterin anabolism|up regulation of tatiopterin formation|positive regulation of tatiopterin formation|activation of tatiopterin synthesis|upregulation of tatiopterin biosynthetic process|upregulation of tatiopterin biosynthesis|up-regulation of tatiopterin anabolism|activation of tatiopterin formation|up-regulation of tatiopterin synthesis|up-regulation of tatiopterin formation|up-regulation of tatiopterin biosynthetic process|up-regulation of tatiopterin biosynthesis|activation of tatiopterin biosynthetic process|upregulation of tatiopterin anabolism|upregulation of tatiopterin synthesis|activation of tatiopterin biosynthesis http://purl.obolibrary.org/obo/GO_1900976 CHEBI:21037 biolink:ChemicalSubstance aldohexose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21037 GO:1900975 biolink:BiologicalProcess negative regulation of tatiopterin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process. go-plus.json negative regulation of tatiopterin biosynthesis|down-regulation of tatiopterin biosynthetic process|down-regulation of tatiopterin biosynthesis|down regulation of tatiopterin synthesis|downregulation of tatiopterin anabolism|down regulation of tatiopterin formation|downregulation of tatiopterin synthesis|downregulation of tatiopterin formation|downregulation of tatiopterin biosynthesis|downregulation of tatiopterin biosynthetic process|down-regulation of tatiopterin anabolism|negative regulation of tatiopterin anabolism|down regulation of tatiopterin biosynthesis|down regulation of tatiopterin biosynthetic process|inhibition of tatiopterin biosynthetic process|down-regulation of tatiopterin synthesis|negative regulation of tatiopterin synthesis|down-regulation of tatiopterin formation|negative regulation of tatiopterin formation|inhibition of tatiopterin biosynthesis|inhibition of tatiopterin anabolism|inhibition of tatiopterin synthesis|down regulation of tatiopterin anabolism|inhibition of tatiopterin formation http://purl.obolibrary.org/obo/GO_1900975 GO:1900978 biolink:BiologicalProcess negative regulation of tatiopterin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process. go-plus.json down-regulation of tatiopterin metabolic process|down-regulation of tatiopterin metabolism|negative regulation of tatiopterin metabolism|inhibition of tatiopterin metabolic process|downregulation of tatiopterin metabolism|down regulation of tatiopterin metabolism|down regulation of tatiopterin metabolic process|downregulation of tatiopterin metabolic process|inhibition of tatiopterin metabolism http://purl.obolibrary.org/obo/GO_1900978 GO:1900977 biolink:BiologicalProcess regulation of tatiopterin metabolic process Any process that modulates the frequency, rate or extent of tatiopterin metabolic process. go-plus.json regulation of tatiopterin metabolism http://purl.obolibrary.org/obo/GO_1900977 GO:1900972 biolink:BiologicalProcess negative regulation of sarcinapterin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process. go-plus.json inhibition of sarcinapterin biosynthesis|inhibition of sarcinapterin anabolism|inhibition of sarcinapterin synthesis|inhibition of sarcinapterin formation|down regulation of sarcinapterin anabolism|down-regulation of sarcinapterin biosynthetic process|down-regulation of sarcinapterin biosynthesis|negative regulation of sarcinapterin biosynthesis|downregulation of sarcinapterin anabolism|down regulation of sarcinapterin synthesis|down regulation of sarcinapterin formation|downregulation of sarcinapterin synthesis|downregulation of sarcinapterin formation|downregulation of sarcinapterin biosynthesis|downregulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin anabolism|down-regulation of sarcinapterin anabolism|down regulation of sarcinapterin biosynthesis|down regulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin synthesis|down-regulation of sarcinapterin synthesis|inhibition of sarcinapterin biosynthetic process|negative regulation of sarcinapterin formation|down-regulation of sarcinapterin formation http://purl.obolibrary.org/obo/GO_1900972 GO:1900971 biolink:BiologicalProcess regulation of sarcinapterin biosynthetic process Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process. go-plus.json regulation of sarcinapterin anabolism|regulation of sarcinapterin synthesis|regulation of sarcinapterin formation|regulation of sarcinapterin biosynthesis http://purl.obolibrary.org/obo/GO_1900971 GO:1900974 biolink:BiologicalProcess regulation of tatiopterin biosynthetic process Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process. go-plus.json regulation of tatiopterin synthesis|regulation of tatiopterin formation|regulation of tatiopterin biosynthesis|regulation of tatiopterin anabolism http://purl.obolibrary.org/obo/GO_1900974 GO:1900973 biolink:BiologicalProcess positive regulation of sarcinapterin biosynthetic process Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process. go-plus.json up-regulation of sarcinapterin anabolism|activation of sarcinapterin formation|up-regulation of sarcinapterin synthesis|up-regulation of sarcinapterin formation|activation of sarcinapterin biosynthetic process|up-regulation of sarcinapterin biosynthetic process|up-regulation of sarcinapterin biosynthesis|upregulation of sarcinapterin anabolism|upregulation of sarcinapterin synthesis|activation of sarcinapterin biosynthesis|upregulation of sarcinapterin formation|up regulation of sarcinapterin anabolism|positive regulation of sarcinapterin biosynthesis|up regulation of sarcinapterin biosynthesis|positive regulation of sarcinapterin anabolism|up regulation of sarcinapterin biosynthetic process|up regulation of sarcinapterin synthesis|positive regulation of sarcinapterin synthesis|up regulation of sarcinapterin formation|activation of sarcinapterin anabolism|positive regulation of sarcinapterin formation|activation of sarcinapterin synthesis|upregulation of sarcinapterin biosynthesis|upregulation of sarcinapterin biosynthetic process http://purl.obolibrary.org/obo/GO_1900973 GO:1900970 biolink:BiologicalProcess positive regulation of sarcinapterin metabolic process Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process. go-plus.json upregulation of sarcinapterin metabolism|up regulation of sarcinapterin metabolic process|activation of sarcinapterin metabolic process|up-regulation of sarcinapterin metabolism|activation of sarcinapterin metabolism|up-regulation of sarcinapterin metabolic process|positive regulation of sarcinapterin metabolism|up regulation of sarcinapterin metabolism|upregulation of sarcinapterin metabolic process http://purl.obolibrary.org/obo/GO_1900970 GO:0022819 biolink:MolecularActivity potassium ion uniporter activity Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged. go-plus.json http://purl.obolibrary.org/obo/GO_0022819 CHEBI:35674 biolink:ChemicalSubstance antihypertensive agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35674 CHEBI:35673 biolink:ChemicalSubstance abietane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35673 chebi_ph7_3 GO:0022818 biolink:MolecularActivity sodium ion uniporter activity Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged. go-plus.json http://purl.obolibrary.org/obo/GO_0022818 CHEBI:59640 biolink:ChemicalSubstance N-acetylglucosamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_59640 CHEBI:35676 biolink:ChemicalSubstance benzazepine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35676 GO:0071869 biolink:BiologicalProcess response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. go-plus.json response to catecholamine stimulus http://purl.obolibrary.org/obo/GO_0071869 GO:0071868 biolink:BiologicalProcess cellular response to monoamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. go-plus.json http://purl.obolibrary.org/obo/GO_0071868 GO:0071867 biolink:BiologicalProcess response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. go-plus.json response to monoamine stimulus http://purl.obolibrary.org/obo/GO_0071867 CHEBI:35679 biolink:ChemicalSubstance antilipemic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35679 GO:0071866 biolink:BiologicalProcess negative regulation of apoptotic process in bone marrow cell Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow. go-plus.json negative regulation of bone marrow cell programmed cell death by apoptosis|negative regulation of apoptosis in bone marrow|negative regulation of bone marrow cell apoptosis|negative regulation of apoptotic process in bone marrow|down-regulation of apoptosis in bone marrow|negative regulation of programmed cell death, bone marrow cells|downregulation of apoptosis in bone marrow|down regulation of apoptosis in bone marrow|negative regulation of killing of bone marrow cells|inhibition of apoptosis in bone marrow|negative regulation of programmed cell death of bone marrow cells by apoptosis http://purl.obolibrary.org/obo/GO_0071866 GO:0071865 biolink:BiologicalProcess regulation of apoptotic process in bone marrow cell Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow. go-plus.json regulation of apoptosis in bone marrow|regulation of apoptotic process in bone marrow http://purl.obolibrary.org/obo/GO_0071865 GO:0022810 biolink:MolecularActivity membrane potential driven uniporter activity Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged. go-plus.json porter http://purl.obolibrary.org/obo/GO_0022810 CHEBI:59648 biolink:ChemicalSubstance precursor Z(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59648 chebi_ph7_3 GO:0071864 biolink:BiologicalProcess positive regulation of cell proliferation in bone marrow A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow. go-plus.json stimulation of cell proliferation in bone marrow|up-regulation of cell proliferation in bone marrow|positive regulation of bone marrow cell proliferation|upregulation of cell proliferation in bone marrow|up regulation of cell proliferation in bone marrow|activation of cell proliferation in bone marrow http://purl.obolibrary.org/obo/GO_0071864 CHEBI:59647 biolink:ChemicalSubstance EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_59647 GO:0071863 biolink:BiologicalProcess regulation of cell proliferation in bone marrow A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow. go-plus.json regulation of bone marrow cell proliferation http://purl.obolibrary.org/obo/GO_0071863 GO:0022815 biolink:MolecularActivity obsolete large uncharged polar molecule transmembrane transporter activity OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other. go-plus.json large uncharged polar molecule transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022815 GO:0071862 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071862 GO:0071861 biolink:MolecularActivity tachykinin receptor binding Binding to a tachykinin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071861 GO:0022814 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022814 CHEBI:59644 biolink:ChemicalSubstance oxo fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59644 GO:0071860 biolink:MolecularActivity proctolin receptor binding Binding to a proctolin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071860 GO:0022817 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022817 CHEBI:59643 biolink:ChemicalSubstance thia fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59643 GO:0022816 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022816 GO:1900987 biolink:BiologicalProcess ajmaline catabolic process The chemical reactions and pathways resulting in the breakdown of ajmaline. go-plus.json ajmaline breakdown|ajmaline catabolism|ajmaline degradation http://purl.obolibrary.org/obo/GO_1900987 GO:1900986 biolink:BiologicalProcess ajmaline metabolic process The chemical reactions and pathways involving ajmaline. go-plus.json ajmaline metabolism http://purl.obolibrary.org/obo/GO_1900986 GO:1900989 biolink:BiologicalProcess scopolamine metabolic process The chemical reactions and pathways involving scopolamine. go-plus.json scopolamine metabolism http://purl.obolibrary.org/obo/GO_1900989 GO:1900988 biolink:BiologicalProcess ajmaline biosynthetic process The chemical reactions and pathways resulting in the formation of ajmaline. go-plus.json ajmaline anabolism|ajmaline synthesis|ajmaline formation|ajmaline biosynthesis http://purl.obolibrary.org/obo/GO_1900988 GO:1900983 biolink:BiologicalProcess vindoline metabolic process The chemical reactions and pathways involving vindoline. go-plus.json vindoline metabolism http://purl.obolibrary.org/obo/GO_1900983 GO:1900982 biolink:BiologicalProcess positive regulation of phenazine biosynthetic process Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process. go-plus.json activation of dibenzo-p-diazine biosynthesis|up-regulation of dibenzopyrazine biosynthetic process|up-regulation of dibenzopyrazine biosynthesis|activation of dibenzo-p-diazine biosynthetic process|up-regulation of azophenylene biosynthesis|up-regulation of azophenylene biosynthetic process|positive regulation of dibenzo-p-diazine biosynthetic process|positive regulation of dibenzo-p-diazine biosynthesis|activation of dibenzopyrazine biosynthetic process|activation of dibenzopyrazine biosynthesis|up regulation of dibenzo-p-diazine biosynthesis|up regulation of dibenzo-p-diazine biosynthetic process|up regulation of acridizine biosynthesis|up-regulation of phenazine biosynthetic process|up regulation of acridizine biosynthetic process|activation of phenazine biosynthetic process|positive regulation of acridizine biosynthetic process|positive regulation of acridizine biosynthesis|positive regulation of dibenzopyrazine biosynthesis|positive regulation of dibenzopyrazine biosynthetic process|upregulation of azophenylene biosynthesis|upregulation of azophenylene biosynthetic process|up regulation of dibenzopyrazine biosynthetic process|up regulation of dibenzopyrazine biosynthesis|activation of acridizine biosynthesis|activation of acridizine biosynthetic process|upregulation of dibenzo-p-diazine biosynthesis|upregulation of dibenzo-p-diazine biosynthetic process|up-regulation of acridizine biosynthesis|up-regulation of acridizine biosynthetic process|up regulation of phenazine biosynthetic process|up regulation of azophenylene biosynthesis|up regulation of azophenylene biosynthetic process|upregulation of dibenzopyrazine biosynthetic process|upregulation of dibenzopyrazine biosynthesis|positive regulation of azophenylene biosynthetic process|positive regulation of azophenylene biosynthesis|up-regulation of dibenzo-p-diazine biosynthetic process|up-regulation of dibenzo-p-diazine biosynthesis|activation of azophenylene biosynthesis|activation of azophenylene biosynthetic process|upregulation of acridizine biosynthetic process|upregulation of acridizine biosynthesis|upregulation of phenazine biosynthetic process http://purl.obolibrary.org/obo/GO_1900982 GO:1900985 biolink:BiologicalProcess vindoline biosynthetic process The chemical reactions and pathways resulting in the formation of vindoline. go-plus.json vindoline anabolism|vindoline biosynthesis|vindoline synthesis|vindoline formation http://purl.obolibrary.org/obo/GO_1900985 GO:1900984 biolink:BiologicalProcess vindoline catabolic process The chemical reactions and pathways resulting in the breakdown of vindoline. go-plus.json vindoline degradation|vindoline breakdown|vindoline catabolism http://purl.obolibrary.org/obo/GO_1900984 NCBITaxon:911341 biolink:OrganismalEntity Heliantheae alliance go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_911341 CHEBI:21040 biolink:ChemicalSubstance D-idarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_21040 chebi_ph7_3 GO:1900981 biolink:BiologicalProcess negative regulation of phenazine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process. go-plus.json negative regulation of dibenzo-p-diazine biosynthesis|down regulation of acridizine biosynthetic process|negative regulation of dibenzo-p-diazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthesis|down regulation of acridizine biosynthesis|downregulation of acridizine biosynthesis|downregulation of acridizine biosynthetic process|down-regulation of dibenzopyrazine biosynthetic process|down-regulation of dibenzopyrazine biosynthesis|negative regulation of dibenzopyrazine biosynthetic process|negative regulation of dibenzopyrazine biosynthesis|inhibition of azophenylene biosynthetic process|inhibition of azophenylene biosynthesis|downregulation of dibenzo-p-diazine biosynthesis|downregulation of dibenzo-p-diazine biosynthetic process|negative regulation of acridizine biosynthesis|down-regulation of acridizine biosynthesis|down regulation of dibenzo-p-diazine biosynthetic process|negative regulation of acridizine biosynthetic process|down-regulation of acridizine biosynthetic process|down regulation of dibenzo-p-diazine biosynthesis|down-regulation of phenazine biosynthetic process|down regulation of azophenylene biosynthesis|down regulation of azophenylene biosynthetic process|downregulation of dibenzopyrazine biosynthesis|downregulation of dibenzopyrazine biosynthetic process|downregulation of azophenylene biosynthesis|downregulation of azophenylene biosynthetic process|down regulation of dibenzopyrazine biosynthetic process|down regulation of dibenzopyrazine biosynthesis|inhibition of dibenzo-p-diazine biosynthesis|inhibition of dibenzo-p-diazine biosynthetic process|downregulation of phenazine biosynthetic process|inhibition of acridizine biosynthesis|inhibition of acridizine biosynthetic process|inhibition of dibenzopyrazine biosynthesis|inhibition of dibenzopyrazine biosynthetic process|down-regulation of azophenylene biosynthetic process|negative regulation of azophenylene biosynthesis|down regulation of phenazine biosynthetic process|negative regulation of azophenylene biosynthetic process|down-regulation of azophenylene biosynthesis|inhibition of phenazine biosynthetic process http://purl.obolibrary.org/obo/GO_1900981 GO:1900980 biolink:BiologicalProcess regulation of phenazine biosynthetic process Any process that modulates the frequency, rate or extent of phenazine biosynthetic process. go-plus.json regulation of acridizine biosynthetic process|regulation of acridizine biosynthesis|regulation of dibenzo-p-diazine biosynthesis|regulation of dibenzo-p-diazine biosynthetic process|regulation of azophenylene biosynthetic process|regulation of azophenylene biosynthesis|regulation of dibenzopyrazine biosynthetic process|regulation of dibenzopyrazine biosynthesis http://purl.obolibrary.org/obo/GO_1900980 CHEBI:21041 biolink:ChemicalSubstance D-idaric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_21041 CHEBI:35684 biolink:ChemicalSubstance antiplatyhelmintic drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35684 GO:0022809 biolink:MolecularActivity mobile ion carrier activity Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane. go-plus.json ionophore http://purl.obolibrary.org/obo/GO_0022809 GO:0071859 biolink:MolecularActivity neuropeptide F receptor binding Binding to a neuropeptide F receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071859 CHEBI:35689 biolink:ChemicalSubstance tetrazoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_35689 GO:0071858 biolink:MolecularActivity corazonin receptor binding Binding to a corazonin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071858 CHEBI:35688 biolink:ChemicalSubstance benzimidazolecarboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35688 GO:0071857 biolink:MolecularActivity beta-endorphin receptor binding Binding to a beta-endorphin receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071857 GO:0071856 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071856 GO:0071855 biolink:MolecularActivity neuropeptide receptor binding Binding to a neuropeptide receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071855 GO:0071854 biolink:BiologicalProcess cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0071854 GO:0071853 biolink:BiologicalProcess fungal-type cell wall disassembly A cellular process that results in the breakdown of a fungal-type cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0071853 GO:0071852 biolink:BiologicalProcess fungal-type cell wall organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall. go-plus.json fungal-type cell wall organisation or biogenesis|fungal-type cell wall organization and biogenesis http://purl.obolibrary.org/obo/GO_0071852 CHEBI:59635 biolink:ChemicalSubstance organophosphonate oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59635 GO:0071851 biolink:BiologicalProcess obsolete mitotic G1 cell cycle arrest in response to nitrogen starvation OBSOLETE. The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen. go-plus.json G1 mitotic cell cycle arrest in response to nitrogen starvation http://purl.obolibrary.org/obo/GO_0071851 GO:0022804 biolink:MolecularActivity active transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. go-plus.json carrier activity|active carrier activity|permease activity|pump activity http://purl.obolibrary.org/obo/GO_0022804 CHEBI:35681 biolink:ChemicalSubstance secondary alcohol go-plus.json http://purl.obolibrary.org/obo/CHEBI_35681 chebi_ph7_3 GO:0022803 biolink:MolecularActivity passive transmembrane transporter activity Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged. Reactome:R-HSA-429767|Wikipedia:Facilitated_diffusion go-plus.json porters|uniporter activity z|facilitated diffusion http://purl.obolibrary.org/obo/GO_0022803 CHEBI:59633 biolink:ChemicalSubstance mycothiol S-conjugate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59633 chebi_ph7_3 GO:0071850 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071850 CHEBI:35680 biolink:ChemicalSubstance abietate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35680 chebi_ph7_3 CHEBI:35683 biolink:ChemicalSubstance aryl sulfide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35683 GO:0032272 biolink:BiologicalProcess negative regulation of protein polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. go-plus.json inhibition of protein polymerization|down-regulation of protein polymerization|downregulation of protein polymerization|down regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032272 GO:0032271 biolink:BiologicalProcess regulation of protein polymerization Any process that modulates the frequency, rate or extent of the process of creating protein polymers. go-plus.json regulation of protein polymerisation http://purl.obolibrary.org/obo/GO_0032271 GO:0032270 biolink:BiologicalProcess positive regulation of cellular protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. go-plus.json positive regulation of cellular protein metabolism|upregulation of cellular protein metabolic process|stimulation of cellular protein metabolic process|up-regulation of cellular protein metabolic process|activation of cellular protein metabolic process|up regulation of cellular protein metabolic process http://purl.obolibrary.org/obo/GO_0032270 CHEBI:60625 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60625 chebi_ph7_3 CHEBI:60627 biolink:ChemicalSubstance N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60627 chebi_ph7_3 GO:0032279 biolink:CellularComponent asymmetric synapse A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory. go-plus.json Gray's type I synapse http://purl.obolibrary.org/obo/GO_0032279 GO:0032278 biolink:BiologicalProcess positive regulation of gonadotropin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin. go-plus.json positive regulation of gonadotrophin secretion|up regulation of gonadotropin secretion|upregulation of gonadotropin secretion|stimulation of gonadotropin secretion|activation of gonadotropin secretion|up-regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0032278 CHEBI:60628 biolink:ChemicalSubstance N(4)-{alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->6)]-alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60628 chebi_ph7_3 GO:0032277 biolink:BiologicalProcess negative regulation of gonadotropin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin. go-plus.json down-regulation of gonadotropin secretion|negative regulation of gonadotrophin secretion|downregulation of gonadotropin secretion|down regulation of gonadotropin secretion|inhibition of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0032277 GO:0032276 biolink:BiologicalProcess regulation of gonadotropin secretion Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin. go-plus.json regulation of gonadotrophin secretion http://purl.obolibrary.org/obo/GO_0032276 GO:0032275 biolink:BiologicalProcess luteinizing hormone secretion The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. go-plus.json http://purl.obolibrary.org/obo/GO_0032275 GO:0032274 biolink:BiologicalProcess gonadotropin secretion The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. go-plus.json gonadotrophin secretion http://purl.obolibrary.org/obo/GO_0032274 GO:0032273 biolink:BiologicalProcess positive regulation of protein polymerization Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. go-plus.json upregulation of protein polymerization|stimulation of protein polymerization|up-regulation of protein polymerization|activation of protein polymerization|up regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032273 NCBITaxon:431838 biolink:OrganismalEntity Intramacronucleata go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_431838 GO:0032261 biolink:BiologicalProcess purine nucleotide salvage Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032261 GO:0032260 biolink:BiologicalProcess response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen. go-plus.json response to jasmonic acid stimulus during jasmonic acid and ethylene-dependent systemic resistance http://purl.obolibrary.org/obo/GO_0032260 GO:0032269 biolink:BiologicalProcess negative regulation of cellular protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. go-plus.json down-regulation of cellular protein metabolic process|downregulation of cellular protein metabolic process|down regulation of cellular protein metabolic process|inhibition of cellular protein metabolic process|negative regulation of cellular protein metabolism http://purl.obolibrary.org/obo/GO_0032269 CHEBI:60637 biolink:ChemicalSubstance N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60637 chebi_ph7_3 GO:0032268 biolink:BiologicalProcess regulation of cellular protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. go-plus.json regulation of cellular protein metabolism http://purl.obolibrary.org/obo/GO_0032268 GO:0032267 biolink:MolecularActivity tRNA(Ile)-lysidine synthase activity Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine. EC:6.3.4.- go-plus.json tRNA(Ile)-lysidine synthetase activity|tRNA(Ile)-2-lysyl-cytidine synthase activity http://purl.obolibrary.org/obo/GO_0032267 GO:0032266 biolink:MolecularActivity phosphatidylinositol-3-phosphate binding Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position. go-plus.json phosphatidylinositol 3-phosphate binding|PtdIns-3-P binding http://purl.obolibrary.org/obo/GO_0032266 GO:0032265 biolink:BiologicalProcess XMP salvage Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032265 GO:0032264 biolink:BiologicalProcess IMP salvage Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032264 GO:0032263 biolink:BiologicalProcess GMP salvage Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032263 GO:0032262 biolink:BiologicalProcess pyrimidine nucleotide salvage Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032262 GO:0032259 biolink:BiologicalProcess methylation The process in which a methyl group is covalently attached to a molecule. Wikipedia:Methylation go-plus.json http://purl.obolibrary.org/obo/GO_0032259 goslim_chembl CHEBI:142797 biolink:ChemicalSubstance TMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142797 chebi_ph7_3 CHEBI:84603 biolink:ChemicalSubstance all-trans-tridecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84603 chebi_ph7_3 CHEBI:142796 biolink:ChemicalSubstance 5-methyl-CMP(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142796 chebi_ph7_3 CHEBI:84602 biolink:ChemicalSubstance all-trans-dodecaprenyl diphosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84602 chebi_ph7_3 GO:0007299 biolink:BiologicalProcess ovarian follicle cell-cell adhesion The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster. go-plus.json ovarian follicle cell adhesion|follicle cell adhesion http://purl.obolibrary.org/obo/GO_0007299 GO:0007298 biolink:BiologicalProcess border follicle cell migration The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster. go-plus.json border cell migration http://purl.obolibrary.org/obo/GO_0007298 CHEBI:84601 biolink:ChemicalSubstance 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydroinden-4-yl]propanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84601 GO:0007297 biolink:BiologicalProcess ovarian follicle cell migration The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster. go-plus.json follicle cell migration http://purl.obolibrary.org/obo/GO_0007297 CHEBI:84600 biolink:ChemicalSubstance all-trans-tridecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84600 GO:0007296 biolink:BiologicalProcess vitellogenesis The production of yolk. Yolk is a mixture of materials used for embryonic nutrition. Wikipedia:Vitellogenesis go-plus.json yolk production|yolk formation http://purl.obolibrary.org/obo/GO_0007296 GO:0007295 biolink:BiologicalProcess growth of a germarium-derived egg chamber Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster. go-plus.json egg chamber growth http://purl.obolibrary.org/obo/GO_0007295 GO:0032250 biolink:BiologicalProcess negative regulation of adenosine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json downregulation of adenosine transport|down-regulation of adenosine transport|inhibition of adenosine transport|down regulation of adenosine transport http://purl.obolibrary.org/obo/GO_0032250 CHEBI:60643 biolink:ChemicalSubstance NMDA receptor antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_60643 CHEBI:60645 biolink:ChemicalSubstance 2-hydroxy-3-methylbutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60645 GO:0032258 biolink:BiologicalProcess cytoplasm to vacuole transport by the Cvt pathway A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast. go-plus.json cytoplasm-to-vacuole targeting|cytoplasm to vacuole targeting|protein localization by the Cvt pathway http://purl.obolibrary.org/obo/GO_0032258 GO:0032257 biolink:BiologicalProcess maintenance of dense core granule location Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of dense core vesicle location|maintenance of dense core granule localization http://purl.obolibrary.org/obo/GO_0032257 GO:0032256 biolink:BiologicalProcess establishment of dense core granule localization The directed movement of a dense core granule to a specific location. go-plus.json establishment of dense core granule localisation|establishment of dense core vesicle localization http://purl.obolibrary.org/obo/GO_0032256 GO:0032255 biolink:BiologicalProcess maintenance of secretory granule location Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere. go-plus.json maintenance of secretory granule localization http://purl.obolibrary.org/obo/GO_0032255 GO:0032254 biolink:BiologicalProcess establishment of secretory granule localization The directed movement of a secretory granule to a specific location. go-plus.json establishment of secretory granule localisation http://purl.obolibrary.org/obo/GO_0032254 GO:0032253 biolink:BiologicalProcess dense core granule localization Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell. go-plus.json dense core granule localisation|dense core vesicle localization|dense core granule clustering http://purl.obolibrary.org/obo/GO_0032253 GO:0032252 biolink:BiologicalProcess secretory granule localization Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. go-plus.json secretory granule clustering|secretory granule localisation http://purl.obolibrary.org/obo/GO_0032252 GO:0032251 biolink:BiologicalProcess positive regulation of adenosine transport Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of adenosine transport|activation of adenosine transport|stimulation of adenosine transport|up-regulation of adenosine transport|upregulation of adenosine transport http://purl.obolibrary.org/obo/GO_0032251 GO:0032249 biolink:BiologicalProcess regulation of adenosine transport Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032249 CHEBI:84618 biolink:ChemicalSubstance 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84618 GO:0032248 biolink:BiologicalProcess positive regulation of purine nucleoside transport Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json upregulation of purine nucleoside transport|up regulation of purine nucleoside transport|activation of purine nucleoside transport|stimulation of purine nucleoside transport|up-regulation of purine nucleoside transport http://purl.obolibrary.org/obo/GO_0032248 CHEBI:84617 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84617 CHEBI:84616 biolink:ChemicalSubstance 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84616 CHEBI:60651 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60651 chebi_ph7_3 CHEBI:60653 biolink:ChemicalSubstance 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60653 CHEBI:60656 biolink:ChemicalSubstance 5-methoxy-2-methyl-3-octaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_60656 chebi_ph7_3 CHEBI:60655 biolink:ChemicalSubstance 6-methoxy-2-octaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_60655 chebi_ph7_3 CHEBI:60657 biolink:ChemicalSubstance 1,2-di-O-arachidonoyl-sn-glycero-3-phosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60657 chebi_ph7_3 GO:0032247 biolink:BiologicalProcess negative regulation of purine nucleoside transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down regulation of purine nucleoside transport|downregulation of purine nucleoside transport|down-regulation of purine nucleoside transport|inhibition of purine nucleoside transport http://purl.obolibrary.org/obo/GO_0032247 GO:0032246 biolink:BiologicalProcess regulation of pyrimidine nucleoside transport Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032246 GO:0032245 biolink:BiologicalProcess regulation of purine nucleoside transport Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032245 GO:0032244 biolink:BiologicalProcess positive regulation of nucleoside transport Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up regulation of nucleoside transport|upregulation of nucleoside transport|stimulation of nucleoside transport|up-regulation of nucleoside transport|activation of nucleoside transport http://purl.obolibrary.org/obo/GO_0032244 GO:0032243 biolink:BiologicalProcess negative regulation of nucleoside transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down-regulation of nucleoside transport|downregulation of nucleoside transport|down regulation of nucleoside transport|inhibition of nucleoside transport http://purl.obolibrary.org/obo/GO_0032243 GO:0032242 biolink:BiologicalProcess regulation of nucleoside transport Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032242 GO:0032241 biolink:BiologicalProcess positive regulation of nucleobase-containing compound transport Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|activation of nucleobase, nucleoside, nucleotide and nucleic acid transport|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport http://purl.obolibrary.org/obo/GO_0032241 GO:0032240 biolink:BiologicalProcess negative regulation of nucleobase-containing compound transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport http://purl.obolibrary.org/obo/GO_0032240 GO:0032239 biolink:BiologicalProcess regulation of nucleobase-containing compound transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport http://purl.obolibrary.org/obo/GO_0032239 GO:0032238 biolink:BiologicalProcess adenosine transport The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032238 GO:0032237 biolink:BiologicalProcess activation of store-operated calcium channel activity A process that initiates the activity of an inactive store-operated calcium channel. go-plus.json http://purl.obolibrary.org/obo/GO_0032237 GO:0046800 biolink:BiologicalProcess obsolete enhancement of virulence OBSOLETE. Any process that activates or increases the severity of viral infection and subsequent disease. go-plus.json enhancement of virulence http://purl.obolibrary.org/obo/GO_0046800 GO:0007279 biolink:BiologicalProcess pole cell formation Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells. go-plus.json http://purl.obolibrary.org/obo/GO_0007279 GO:0007278 biolink:BiologicalProcess pole cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0007278 GO:0007277 biolink:BiologicalProcess pole cell development The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure. go-plus.json http://purl.obolibrary.org/obo/GO_0007277 GO:0007276 biolink:BiologicalProcess gamete generation The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. go-plus.json gametogenesis http://purl.obolibrary.org/obo/GO_0007276 GO:0007275 biolink:BiologicalProcess multicellular organism development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). go-plus.json http://purl.obolibrary.org/obo/GO_0007275 goslim_chembl|gocheck_do_not_annotate|goslim_plant GO:0007274 biolink:BiologicalProcess neuromuscular synaptic transmission The process of synaptic transmission from a neuron to a muscle, across a synapse. go-plus.json http://purl.obolibrary.org/obo/GO_0007274 GO:0007273 biolink:BiologicalProcess obsolete regulation of synapse OBSOLETE. (Was not defined before being made obsolete). go-plus.json regulation of synapse http://purl.obolibrary.org/obo/GO_0007273 GO:0007283 biolink:BiologicalProcess spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. Wikipedia:Spermatogenesis go-plus.json generation of spermatozoa http://purl.obolibrary.org/obo/GO_0007283 GO:0046808 biolink:CellularComponent obsolete assemblon OBSOLETE. Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously. go-plus.json http://purl.obolibrary.org/obo/GO_0046808 GO:0007282 biolink:BiologicalProcess cystoblast division Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells. go-plus.json cystoblast cell division http://purl.obolibrary.org/obo/GO_0007282 GO:0046807 biolink:BiologicalProcess viral scaffold assembly and maintenance The assembly and maintenance of the viral scaffold around which the viral capsid is constructed. go-plus.json http://purl.obolibrary.org/obo/GO_0046807 GO:0007281 biolink:BiologicalProcess germ cell development The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. go-plus.json primordial germ cell development|germ-cell development http://purl.obolibrary.org/obo/GO_0007281 GO:0046806 biolink:CellularComponent viral scaffold A complex of proteins that form a scaffold around which the viral capsid is constructed. go-plus.json http://purl.obolibrary.org/obo/GO_0046806 GO:0007280 biolink:BiologicalProcess pole cell migration The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form. go-plus.json http://purl.obolibrary.org/obo/GO_0007280 GO:0046805 biolink:BiologicalProcess protein-heme linkage via 1'-L-histidine The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine). RESID:AA0329 go-plus.json protein-haem linkage via 1'-L-histidine http://purl.obolibrary.org/obo/GO_0046805 GO:0046804 biolink:BiologicalProcess peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine. RESID:AA0330 go-plus.json peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulphoxide http://purl.obolibrary.org/obo/GO_0046804 GO:0046803 biolink:BiologicalProcess obsolete reduction of virulence OBSOLETE. Any process that stops, prevents or reduces the severity of viral infection and subsequent disease. go-plus.json reduction of virulence http://purl.obolibrary.org/obo/GO_0046803 GO:0046802 biolink:BiologicalProcess exit of virus from host cell nucleus by nuclear egress The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm. VZ:1952 go-plus.json capsid egress|nuclear egress|egress of viral procapsid from host cell nucleus|nuclear egress of viral procapsid http://purl.obolibrary.org/obo/GO_0046802 GO:0046801 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046801 GO:0032236 biolink:BiologicalProcess obsolete positive regulation of calcium ion transport via store-operated calcium channel activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel. go-plus.json up regulation of calcium ion transport via store-operated calcium channel|positive regulation of calcium ion transport via store-operated calcium channel activity|upregulation of calcium ion transport via store-operated calcium channel|positive regulation of store-operated calcium channel activity|stimulation of calcium ion transport via store-operated calcium channel|up-regulation of calcium ion transport via store-operated calcium channel|activation of calcium ion transport via store-operated calcium channel|positive regulation of calcium transport via store-operated calcium channel http://purl.obolibrary.org/obo/GO_0032236 GO:0032235 biolink:BiologicalProcess obsolete negative regulation of calcium ion transport via store-operated calcium channel activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel. go-plus.json downregulation of calcium ion transport via store-operated calcium channel|negative regulation of calcium ion transport via store-operated calcium channel activity|down regulation of calcium ion transport via store-operated calcium channel|inhibition of calcium ion transport via store-operated calcium channel|negative regulation of calcium transport via store-operated calcium channel|negative regulation of store-operated calcium channel activity|down-regulation of calcium ion transport via store-operated calcium channel http://purl.obolibrary.org/obo/GO_0032235 GO:0032234 biolink:BiologicalProcess obsolete regulation of calcium ion transport via store-operated calcium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel. go-plus.json regulation of calcium transport via store-operated calcium channel|regulation of store-operated calcium channel activity|regulation of calcium ion transport via store-operated calcium channel activity http://purl.obolibrary.org/obo/GO_0032234 GO:0032233 biolink:BiologicalProcess positive regulation of actin filament bundle assembly Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. go-plus.json upregulation of actin filament bundle formation|up regulation of actin filament bundle formation|activation of actin filament bundle formation|stimulation of actin filament bundle formation|up-regulation of actin filament bundle formation http://purl.obolibrary.org/obo/GO_0032233 GO:0032232 biolink:BiologicalProcess negative regulation of actin filament bundle assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. go-plus.json down regulation of actin filament bundle formation|downregulation of actin filament bundle formation|down-regulation of actin filament bundle formation|inhibition of actin filament bundle formation http://purl.obolibrary.org/obo/GO_0032232 GO:0032231 biolink:BiologicalProcess regulation of actin filament bundle assembly Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. go-plus.json regulation of actin filament bundle formation|regulation of actin cable assembly http://purl.obolibrary.org/obo/GO_0032231 GO:0032230 biolink:BiologicalProcess positive regulation of synaptic transmission, GABAergic Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). go-plus.json upregulation of synaptic transmission, GABAergic|stimulation of synaptic transmission, GABAergic|up-regulation of synaptic transmission, GABAergic|activation of synaptic transmission, GABAergic|up regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0032230 GO:0046809 biolink:CellularComponent replication compartment Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously. go-plus.json RC http://purl.obolibrary.org/obo/GO_0046809 GO:0032229 biolink:BiologicalProcess negative regulation of synaptic transmission, GABAergic Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). go-plus.json down-regulation of synaptic transmission, GABAergic|downregulation of synaptic transmission, GABAergic|down regulation of synaptic transmission, GABAergic|inhibition of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0032229 GO:0032228 biolink:BiologicalProcess regulation of synaptic transmission, GABAergic Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). go-plus.json http://purl.obolibrary.org/obo/GO_0032228 GO:0032227 biolink:BiologicalProcess negative regulation of synaptic transmission, dopaminergic Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. go-plus.json inhibition of synaptic transmission, dopaminergic|down regulation of synaptic transmission, dopaminergic|downregulation of synaptic transmission, dopaminergic|down-regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0032227 GO:0032226 biolink:BiologicalProcess positive regulation of synaptic transmission, dopaminergic Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. go-plus.json up-regulation of synaptic transmission, dopaminergic|upregulation of synaptic transmission, dopaminergic|up regulation of synaptic transmission, dopaminergic|activation of synaptic transmission, dopaminergic|stimulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0032226 GO:0046811 biolink:MolecularActivity histone deacetylase inhibitor activity Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes. go-plus.json http://purl.obolibrary.org/obo/GO_0046811 GO:0046810 biolink:MolecularActivity host cell extracellular matrix binding Binding to the extracellular matrix of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0046810 GO:0007289 biolink:BiologicalProcess spermatid nucleus differentiation The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization. go-plus.json spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_0007289 GO:0007288 biolink:BiologicalProcess sperm axoneme assembly The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. go-plus.json http://purl.obolibrary.org/obo/GO_0007288 GO:0007287 biolink:BiologicalProcess Nebenkern assembly Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern. go-plus.json Nebenkern assembly|Nebenkern formation http://purl.obolibrary.org/obo/GO_0007287 CHEBI:84634 biolink:ChemicalSubstance O-tetradecanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84634 chebi_ph7_3 GO:0007286 biolink:BiologicalProcess spermatid development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. Wikipedia:Spermiogenesis go-plus.json spermatid cell development|spermiogenesis http://purl.obolibrary.org/obo/GO_0007286 GO:0007285 biolink:BiologicalProcess primary spermatocyte growth The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis. go-plus.json http://purl.obolibrary.org/obo/GO_0007285 GO:0007284 biolink:BiologicalProcess spermatogonial cell division The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes). go-plus.json spermatogonium division http://purl.obolibrary.org/obo/GO_0007284 GO:0046819 biolink:BiologicalProcess protein secretion by the type V secretion system The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway. go-plus.json autotransporter system|type V protein secretion system|protein secretion by the autotransporter system|protein secretion by the type V protein secretion system http://purl.obolibrary.org/obo/GO_0046819 GO:0007294 biolink:BiologicalProcess germarium-derived oocyte fate determination The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster. go-plus.json maintenance of oocyte identity|oocyte cell fate determination http://purl.obolibrary.org/obo/GO_0007294 GO:0046818 biolink:CellularComponent dense nuclear body A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously. go-plus.json http://purl.obolibrary.org/obo/GO_0046818 GO:0007293 biolink:BiologicalProcess germarium-derived egg chamber formation Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007293 GO:0046817 biolink:MolecularActivity chemokine receptor antagonist activity Interacts with chemokine receptors to reduce the action of a chemokine. go-plus.json http://purl.obolibrary.org/obo/GO_0046817 GO:0007292 biolink:BiologicalProcess female gamete generation Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. go-plus.json http://purl.obolibrary.org/obo/GO_0007292 GO:0046816 biolink:CellularComponent virion transport vesicle A vesicle used to transport the partial or complete virion between cellular compartments. go-plus.json http://purl.obolibrary.org/obo/GO_0046816 GO:0007291 biolink:BiologicalProcess sperm individualization The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0007291 GO:0046815 biolink:BiologicalProcess genome retention in viral capsid Any process in which the viral genome is retained within the capsid during genome cleavage and packaging. go-plus.json http://purl.obolibrary.org/obo/GO_0046815 GO:0007290 biolink:BiologicalProcess spermatid nucleus elongation The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation. go-plus.json spermatid nuclear elongation http://purl.obolibrary.org/obo/GO_0007290 GO:0046814 biolink:BiologicalProcess coreceptor-mediated virion attachment to host cell The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface. go-plus.json virion attachment, binding of host cell surface coreceptor http://purl.obolibrary.org/obo/GO_0046814 GO:0046813 biolink:BiologicalProcess receptor-mediated virion attachment to host cell The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface. go-plus.json virion attachment, binding of host cell surface receptor http://purl.obolibrary.org/obo/GO_0046813 CHEBI:142767 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-yl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_142767 GO:0046812 biolink:MolecularActivity host cell surface binding Binding to the surface of a host cell. go-plus.json http://purl.obolibrary.org/obo/GO_0046812 goslim_pir GO:0032225 biolink:BiologicalProcess regulation of synaptic transmission, dopaminergic Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. go-plus.json http://purl.obolibrary.org/obo/GO_0032225 NCBITaxon:1508594 biolink:OrganismalEntity Chloroflexineae go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_1508594 GO:0032224 biolink:BiologicalProcess positive regulation of synaptic transmission, cholinergic Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. go-plus.json upregulation of synaptic transmission, cholinergic|stimulation of synaptic transmission, cholinergic|up-regulation of synaptic transmission, cholinergic|activation of synaptic transmission, cholinergic|up regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032224 GO:0032223 biolink:BiologicalProcess negative regulation of synaptic transmission, cholinergic Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. go-plus.json down regulation of synaptic transmission, cholinergic|inhibition of synaptic transmission, cholinergic|down-regulation of synaptic transmission, cholinergic|downregulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032223 GO:0032222 biolink:BiologicalProcess regulation of synaptic transmission, cholinergic Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. go-plus.json http://purl.obolibrary.org/obo/GO_0032222 GO:0032221 biolink:CellularComponent Rpd3S/Clr6-CII complex A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species). go-plus.json Rpd3S complex|Clr6S complex|Clr6 histone deacetylase complex II|Rpd3C(S)|Clr6 histone deacetylase complex II'|Clr6-CII http://purl.obolibrary.org/obo/GO_0032221 GO:0032220 biolink:BiologicalProcess plasma membrane fusion involved in cytogamy The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy. go-plus.json plasma membrane fusion during cytogamy|plasma membrane organization involved in conjugation with cellular fusion http://purl.obolibrary.org/obo/GO_0032220 GO:0022891 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022891 GO:0022890 biolink:MolecularActivity inorganic cation transmembrane transporter activity Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage. go-plus.json trivalent inorganic cation transmembrane transporter activity|divalent inorganic cation transmembrane transporter activity|monovalent inorganic cation transmembrane transporter activity|di-, tri-valent inorganic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022890 GO:0022893 biolink:MolecularActivity low-affinity tryptophan transmembrane transporter activity Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. go-plus.json low-affinity tryptophan permease activity http://purl.obolibrary.org/obo/GO_0022893 GO:0032219 biolink:BiologicalProcess cell wall macromolecule catabolic process involved in cytogamy The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy. go-plus.json cell wall macromolecule catabolic process during cytogamy http://purl.obolibrary.org/obo/GO_0032219 GO:0022892 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022892 GO:0032218 biolink:BiologicalProcess riboflavin transport The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins. go-plus.json http://purl.obolibrary.org/obo/GO_0032218 GO:0022895 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0022895 GO:0032217 biolink:MolecularActivity riboflavin transmembrane transporter activity Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins. RHEA:35015|Reactome:R-HSA-3165230 go-plus.json riboflavin transporter activity http://purl.obolibrary.org/obo/GO_0032217 GO:0022894 biolink:MolecularActivity Intermediate conductance calcium-activated potassium channel activity Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. go-plus.json intermdiate conductance KCa channels|IK KCa channels|IK calcium-activated potassium channel activity http://purl.obolibrary.org/obo/GO_0022894 GO:0032216 biolink:MolecularActivity glucosaminyl-phosphatidylinositol O-acyltransferase activity Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA. go-plus.json glucosaminyl-phosphotidylinositol O-acyltransferase activity|GPI-inositol acyltransferase http://purl.obolibrary.org/obo/GO_0032216 GO:0022897 biolink:MolecularActivity proton-dependent peptide secondary active transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement. go-plus.json hydrogen/oligopeptide symporter http://purl.obolibrary.org/obo/GO_0022897 GO:0032215 biolink:BiologicalProcess positive regulation of telomere maintenance via semi-conservative replication Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA. go-plus.json up regulation of telomere maintenance via semi-conservative replication|upregulation of telomere maintenance via semi-conservative replication|stimulation of telomere maintenance via semi-conservative replication|activation of telomere maintenance via semi-conservative replication|up-regulation of telomere maintenance via semi-conservative replication http://purl.obolibrary.org/obo/GO_0032215 GO:0007259 biolink:BiologicalProcess receptor signaling pathway via JAK-STAT Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins. Wikipedia:JAK-STAT_signaling_pathway go-plus.json JAK-STAT signal transduction|JAK-STAT cascade http://purl.obolibrary.org/obo/GO_0007259 CHEBI:84649 biolink:ChemicalSubstance O-[(5Z)-tetradecenoyl]-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84649 chebi_ph7_3 GO:0046822 biolink:BiologicalProcess regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. go-plus.json http://purl.obolibrary.org/obo/GO_0046822 GO:0007258 biolink:BiologicalProcess JUN phosphorylation The process of introducing a phosphate group into a JUN protein. go-plus.json http://purl.obolibrary.org/obo/GO_0007258 GO:0046821 biolink:CellularComponent extrachromosomal DNA DNA structures that are not part of a chromosome. Wikipedia:Extrachromosomal_DNA go-plus.json http://purl.obolibrary.org/obo/GO_0046821 GO:0007257 biolink:BiologicalProcess obsolete activation of JUN kinase activity OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase (JNK). go-plus.json activation of SAPK activity http://purl.obolibrary.org/obo/GO_0007257 GO:0007256 biolink:BiologicalProcess obsolete activation of JNKK activity OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress. go-plus.json positive regulation of JUNKK activity|activation of JUN kinase kinase activity http://purl.obolibrary.org/obo/GO_0007256 GO:0046820 biolink:MolecularActivity 4-amino-4-deoxychorismate synthase activity Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate. EC:2.6.1.85|RHEA:11672|MetaCyc:PABASYN-RXN|KEGG_REACTION:R01716 go-plus.json chorismate:L-glutamine amido-ligase activity|p-aminobenzoate synthetase|para-aminobenzoic acid synthase activity|PabB activity|ADC synthase activity|aminodeoxychorismate synthase activity|para-aminobenzoic acid (PABA) synthase http://purl.obolibrary.org/obo/GO_0046820 CHEBI:84647 biolink:ChemicalSubstance O-[(9Z)-tetradecenoyl]-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84647 chebi_ph7_3 GO:0007255 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007255 CHEBI:84645 biolink:ChemicalSubstance (R)-icosanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84645 chebi_ph7_3 GO:0007254 biolink:BiologicalProcess JNK cascade An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. go-plus.json MAPK10 cascade|JNK3 cascade|JNK2 cascade|JNK1 cascade|MAPK9 cascade|MAPK8 cascade|SAPK cascade|stress-activated protein kinase cascade|c-Jun N-terminal kinase cascade http://purl.obolibrary.org/obo/GO_0007254 GO:0007253 biolink:BiologicalProcess cytoplasmic sequestering of NF-kappaB The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. go-plus.json cytoplasmic storage of NF-kappaB|cytoplasmic retention of NF-kappaB|maintenance of NF-kappaB location in cytoplasm|cytoplasmic NF-kappaB retention|cytoplasmic NF-kappaB storage|cytoplasmic sequestration of NF-kappaB|cytoplasmic NF-kappaB sequestration http://purl.obolibrary.org/obo/GO_0007253 CHEBI:84644 biolink:ChemicalSubstance O-octadecanoyl-L-carnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84644 chebi_ph7_3 GO:0007252 biolink:BiologicalProcess I-kappaB phosphorylation The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. go-plus.json IkappaB phosphorylation|IKB phosphorylation|inhibitor of NF-kappaB phosphorylation|inhibitor of kappaB phosphorylation http://purl.obolibrary.org/obo/GO_0007252 GO:0007251 biolink:BiologicalProcess obsolete activation of the inhibitor of kappa kinase OBSOLETE. (Was not defined before being made obsolete). go-plus.json activation of the inhibitor of kappa kinase http://purl.obolibrary.org/obo/GO_0007251 GO:0007261 biolink:BiologicalProcess obsolete JAK-induced STAT protein dimerization OBSOLETE. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases. go-plus.json JAK-induced STAT protein dimerization http://purl.obolibrary.org/obo/GO_0007261 GO:0007260 biolink:BiologicalProcess tyrosine phosphorylation of STAT protein The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. go-plus.json tyrosine phosphorylation of Stat7 protein|tyrosine phosphorylation of Stat6 protein|tyrosine phosphorylation of Stat5 protein|tyrosine phosphorylation of Stat4 protein|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat2 protein|tyrosine phosphorylation of Stat1 protein http://purl.obolibrary.org/obo/GO_0007260 GO:0046829 biolink:BiologicalProcess negative regulation of RNA import into nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus. go-plus.json down-regulation of RNA import into nucleus|negative regulation of RNA import into cell nucleus|inhibition of RNA import into nucleus|negative regulation of RNA transport from cytoplasm to nucleus|down regulation of RNA import into nucleus|downregulation of RNA import into nucleus|negative regulation of RNA-nucleus import http://purl.obolibrary.org/obo/GO_0046829 GO:0046828 biolink:BiologicalProcess regulation of RNA import into nucleus Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus. go-plus.json regulation of RNA transport from cytoplasm to nucleus|regulation of RNA-nucleus import|regulation of RNA import into cell nucleus http://purl.obolibrary.org/obo/GO_0046828 CHEBI:60687 biolink:ChemicalSubstance cembrane diterpenoid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60687 GO:0046827 biolink:BiologicalProcess positive regulation of protein export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. go-plus.json positive regulation of protein export from cell nucleus|up regulation of protein export from nucleus|activation of protein export from nucleus|positive regulation of protein export out of nucleus|stimulation of protein export from nucleus|up-regulation of protein export from nucleus|positive regulation of protein-nucleus export|positive regulation of protein transport from nucleus to cytoplasm|upregulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046827 GO:0046826 biolink:BiologicalProcess negative regulation of protein export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm. go-plus.json down-regulation of protein export from nucleus|negative regulation of protein export out of nucleus|negative regulation of protein-nucleus export|inhibition of protein export from nucleus|down regulation of protein export from nucleus|negative regulation of protein transport from nucleus to cytoplasm|negative regulation of protein export from cell nucleus|downregulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046826 CHEBI:60689 biolink:ChemicalSubstance cembrane go-plus.json http://purl.obolibrary.org/obo/CHEBI_60689 chebi_ph7_3 GO:0046825 biolink:BiologicalProcess regulation of protein export from nucleus Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. go-plus.json regulation of protein export from cell nucleus|regulation of protein transport from nucleus to cytoplasm|regulation of protein-nucleus export|regulation of protein export out of nucleus http://purl.obolibrary.org/obo/GO_0046825 GO:0046824 biolink:BiologicalProcess positive regulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. go-plus.json up-regulation of nucleocytoplasmic transport|upregulation of nucleocytoplasmic transport|up regulation of nucleocytoplasmic transport|activation of nucleocytoplasmic transport|stimulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046824 GO:0046823 biolink:BiologicalProcess negative regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. go-plus.json inhibition of nucleocytoplasmic transport|down regulation of nucleocytoplasmic transport|downregulation of nucleocytoplasmic transport|down-regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046823 GO:0032214 biolink:BiologicalProcess negative regulation of telomere maintenance via semi-conservative replication Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA. go-plus.json downregulation of telomere maintenance via semi-conservative replication|down regulation of telomere maintenance via semi-conservative replication|inhibition of telomere maintenance via semi-conservative replication|down-regulation of telomere maintenance via semi-conservative replication http://purl.obolibrary.org/obo/GO_0032214 GO:0032213 biolink:BiologicalProcess regulation of telomere maintenance via semi-conservative replication Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0032213 GO:0022898 biolink:BiologicalProcess regulation of transmembrane transporter activity Any process that modulates the frequency, rate or extent of transmembrane transporter activity. go-plus.json http://purl.obolibrary.org/obo/GO_0022898 GO:0032212 biolink:BiologicalProcess positive regulation of telomere maintenance via telomerase Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase. go-plus.json up-regulation of telomere maintenance via telomerase activity|up regulation of telomere maintenance via telomerase activity|activation of telomere maintenance via telomerase|stimulation of telomere maintenance via telomerase|upregulation of telomere maintenance via telomerase activity http://purl.obolibrary.org/obo/GO_0032212 GO:0032211 biolink:BiologicalProcess negative regulation of telomere maintenance via telomerase Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. go-plus.json inhibition of telomere maintenance via telomerase|down-regulation of telomere maintenance via telomerase activity|downregulation of telomere maintenance via telomerase activity|down regulation of telomere maintenance via telomerase activity http://purl.obolibrary.org/obo/GO_0032211 GO:0032210 biolink:BiologicalProcess regulation of telomere maintenance via telomerase Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase. go-plus.json http://purl.obolibrary.org/obo/GO_0032210 GO:1900903 biolink:BiologicalProcess negative regulation of hexadecanal biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process. go-plus.json inhibition of hexadecanal synthesis|negative regulation of hexadecanal formation|down-regulation of hexadecanal formation|inhibition of hexadecanal formation|down regulation of palmitaldehyde biosynthesis|down regulation of palmitaldehyde biosynthetic process|downregulation of palmitaldehyde biosynthetic process|downregulation of palmitaldehyde biosynthesis|down regulation of hexadecanal anabolism|down-regulation of hexadecanal biosynthetic process|down regulation of hexadecanal synthesis|downregulation of hexadecanal anabolism|down-regulation of hexadecanal biosynthesis|negative regulation of hexadecanal biosynthesis|down regulation of hexadecanal formation|negative regulation of palmitaldehyde biosynthesis|negative regulation of palmitaldehyde biosynthetic process|down-regulation of palmitaldehyde biosynthetic process|down-regulation of palmitaldehyde biosynthesis|downregulation of hexadecanal synthesis|downregulation of hexadecanal biosynthetic process|inhibition of palmitaldehyde biosynthesis|inhibition of palmitaldehyde biosynthetic process|downregulation of hexadecanal formation|negative regulation of hexadecanal anabolism|down-regulation of hexadecanal anabolism|down regulation of hexadecanal biosynthetic process|downregulation of hexadecanal biosynthesis|inhibition of hexadecanal biosynthetic process|inhibition of hexadecanal biosynthesis|inhibition of hexadecanal anabolism|negative regulation of hexadecanal synthesis|down-regulation of hexadecanal synthesis|down regulation of hexadecanal biosynthesis http://purl.obolibrary.org/obo/GO_1900903 GO:0022880 biolink:MolecularActivity protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json N-acetylglucosamine PTS transporter activity http://purl.obolibrary.org/obo/GO_0022880 GO:1900902 biolink:BiologicalProcess regulation of hexadecanal biosynthetic process Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process. go-plus.json regulation of palmitaldehyde biosynthetic process|regulation of palmitaldehyde biosynthesis|regulation of hexadecanal anabolism|regulation of hexadecanal synthesis|regulation of hexadecanal formation|regulation of hexadecanal biosynthesis http://purl.obolibrary.org/obo/GO_1900902 GO:0032209 biolink:BiologicalProcess positive regulation of telomere maintenance via recombination Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length. go-plus.json stimulation of telomere maintenance via recombination|up-regulation of telomere maintenance via recombination|activation of telomere maintenance via recombination|up regulation of telomere maintenance via recombination|upregulation of telomere maintenance via recombination http://purl.obolibrary.org/obo/GO_0032209 GO:1900905 biolink:BiologicalProcess regulation of hexadecanal metabolic process Any process that modulates the frequency, rate or extent of hexadecanal metabolic process. go-plus.json regulation of hexadecanal metabolism http://purl.obolibrary.org/obo/GO_1900905 GO:0022882 biolink:MolecularActivity protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json beta-glucoside PTS transporter activity http://purl.obolibrary.org/obo/GO_0022882 CHEBI:45075 biolink:ChemicalSubstance 7-cyano-7-deazaguanine go-plus.json http://purl.obolibrary.org/obo/CHEBI_45075 chebi_ph7_3 GO:0022881 biolink:MolecularActivity protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. go-plus.json N-acetylgalactosamine PTS transporter activity http://purl.obolibrary.org/obo/GO_0022881 GO:1900904 biolink:BiologicalProcess positive regulation of hexadecanal biosynthetic process Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process. go-plus.json up-regulation of hexadecanal anabolism|upregulation of hexadecanal biosynthesis|up-regulation of hexadecanal synthesis|upregulation of palmitaldehyde biosynthesis|upregulation of palmitaldehyde biosynthetic process|activation of hexadecanal biosynthetic process|up-regulation of hexadecanal biosynthetic process|activation of hexadecanal biosynthesis|up-regulation of hexadecanal formation|upregulation of hexadecanal anabolism|activation of palmitaldehyde biosynthesis|up-regulation of hexadecanal biosynthesis|upregulation of hexadecanal synthesis|up regulation of palmitaldehyde biosynthetic process|up regulation of palmitaldehyde biosynthesis|activation of hexadecanal anabolism|upregulation of hexadecanal formation|positive regulation of palmitaldehyde biosynthetic process|positive regulation of palmitaldehyde biosynthesis|up regulation of hexadecanal biosynthetic process|activation of hexadecanal synthesis|up regulation of hexadecanal anabolism|positive regulation of hexadecanal anabolism|positive regulation of hexadecanal biosynthesis|activation of palmitaldehyde biosynthetic process|activation of hexadecanal formation|up regulation of hexadecanal biosynthesis|up regulation of hexadecanal synthesis|positive regulation of hexadecanal synthesis|up regulation of hexadecanal formation|up-regulation of palmitaldehyde biosynthesis|up-regulation of palmitaldehyde biosynthetic process|positive regulation of hexadecanal formation|upregulation of hexadecanal biosynthetic process http://purl.obolibrary.org/obo/GO_1900904 GO:0032208 biolink:BiologicalProcess negative regulation of telomere maintenance via recombination Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length. go-plus.json down-regulation of telomere maintenance via recombination|downregulation of telomere maintenance via recombination|down regulation of telomere maintenance via recombination|inhibition of telomere maintenance via recombination http://purl.obolibrary.org/obo/GO_0032208 GO:0022884 biolink:MolecularActivity macromolecule transmembrane transporter activity Enables the transfer of a macromolecule from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0022884 GO:0032207 biolink:BiologicalProcess regulation of telomere maintenance via recombination Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length. go-plus.json http://purl.obolibrary.org/obo/GO_0032207 GO:0032206 biolink:BiologicalProcess positive regulation of telomere maintenance Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. go-plus.json upregulation of telomere maintenance|stimulation of telomere maintenance|up-regulation of telomere maintenance|activation of telomere maintenance|up regulation of telomere maintenance http://purl.obolibrary.org/obo/GO_0032206 GO:0022883 biolink:MolecularActivity zinc efflux transmembrane transporter activity Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane. go-plus.json zinc efflux permease activity http://purl.obolibrary.org/obo/GO_0022883 GO:0032205 biolink:BiologicalProcess negative regulation of telomere maintenance Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. go-plus.json inhibition of telomere maintenance|down-regulation of telomere maintenance|downregulation of telomere maintenance|down regulation of telomere maintenance http://purl.obolibrary.org/obo/GO_0032205 GO:1900901 biolink:BiologicalProcess positive regulation of heptadecane metabolic process Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process. go-plus.json up regulation of heptadecane metabolic process|activation of heptadecane metabolic process|upregulation of heptadecane metabolism|activation of heptadecane metabolism|up-regulation of heptadecane metabolic process|up-regulation of heptadecane metabolism|upregulation of heptadecane metabolic process|positive regulation of heptadecane metabolism|up regulation of heptadecane metabolism http://purl.obolibrary.org/obo/GO_1900901 GO:0022886 biolink:MolecularActivity channel-forming ionophore activity Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive. go-plus.json ionophore activity http://purl.obolibrary.org/obo/GO_0022886 GO:1900900 biolink:BiologicalProcess negative regulation of heptadecane metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process. go-plus.json down regulation of heptadecane metabolism|down-regulation of heptadecane metabolic process|inhibition of heptadecane metabolic process|negative regulation of heptadecane metabolism|down-regulation of heptadecane metabolism|down regulation of heptadecane metabolic process|downregulation of heptadecane metabolic process|inhibition of heptadecane metabolism|downregulation of heptadecane metabolism http://purl.obolibrary.org/obo/GO_1900900 GO:0022885 biolink:MolecularActivity bacteriocin transmembrane transporter activity Enables the transfer of a bacteriocin from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0022885 GO:0032204 biolink:BiologicalProcess regulation of telomere maintenance Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. go-plus.json http://purl.obolibrary.org/obo/GO_0032204 GO:0007269 biolink:BiologicalProcess neurotransmitter secretion The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. go-plus.json neurotransmitter secretory pathway|neurotransmitter release http://purl.obolibrary.org/obo/GO_0007269 goslim_synapse GO:0046833 biolink:BiologicalProcess positive regulation of RNA export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm. go-plus.json positive regulation of RNA transport from nucleus to cytoplasm|upregulation of RNA export from nucleus|up regulation of RNA export from nucleus|positive regulation of RNA export from cell nucleus|activation of RNA export from nucleus|positive regulation of RNA export out of nucleus|stimulation of RNA export from nucleus|up-regulation of RNA export from nucleus|positive regulation of RNA-nucleus export http://purl.obolibrary.org/obo/GO_0046833 GO:0007268 biolink:BiologicalProcess chemical synaptic transmission The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. Wikipedia:Neurotransmission go-plus.json neurotransmission|synaptic transmission|signal transmission across a synapse http://purl.obolibrary.org/obo/GO_0007268 goslim_synapse GO:0046832 biolink:BiologicalProcess negative regulation of RNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm. go-plus.json down regulation of RNA export from nucleus|negative regulation of RNA transport from nucleus to cytoplasm|downregulation of RNA export from nucleus|negative regulation of RNA export from cell nucleus|down-regulation of RNA export from nucleus|negative regulation of RNA export out of nucleus|inhibition of RNA export from nucleus|negative regulation of RNA-nucleus export http://purl.obolibrary.org/obo/GO_0046832 CHEBI:60690 biolink:ChemicalSubstance nitrogen-containing fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60690 GO:0007267 biolink:BiologicalProcess cell-cell signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. go-plus.json cell-cell signalling http://purl.obolibrary.org/obo/GO_0007267 goslim_plant|goslim_generic|goslim_chembl GO:0046831 biolink:BiologicalProcess regulation of RNA export from nucleus Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm. go-plus.json regulation of RNA-nucleus export|regulation of RNA export out of nucleus|regulation of RNA export from cell nucleus|regulation of RNA transport from nucleus to cytoplasm http://purl.obolibrary.org/obo/GO_0046831 GO:0007266 biolink:BiologicalProcess Rho protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. go-plus.json Rho mediated signal transduction http://purl.obolibrary.org/obo/GO_0007266 GO:0046830 biolink:BiologicalProcess positive regulation of RNA import into nucleus Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus. go-plus.json up regulation of RNA import into nucleus|activation of RNA import into nucleus|stimulation of RNA import into nucleus|positive regulation of RNA-nucleus import|positive regulation of RNA import into cell nucleus|up-regulation of RNA import into nucleus|positive regulation of RNA transport from cytoplasm to nucleus|upregulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046830 GO:0007265 biolink:BiologicalProcess Ras protein signal transduction A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state. go-plus.json Ras mediated signal transduction http://purl.obolibrary.org/obo/GO_0007265 CHEBI:84656 biolink:ChemicalSubstance alpha-Neu5Ac-(2->3)-beta-D-Gal(1->3)beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer(d18:1/18:0) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84656 GO:0007264 biolink:BiologicalProcess small GTPase mediated signal transduction Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. go-plus.json small GTPase-mediated signal transduction http://purl.obolibrary.org/obo/GO_0007264 CHEBI:60691 biolink:ChemicalSubstance aza fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60691 GO:0007263 biolink:BiologicalProcess nitric oxide mediated signal transduction Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms. go-plus.json NO-mediated signal transduction|NO mediated signal transduction|nitric oxide-mediated signal transduction|nitric oxide signaling http://purl.obolibrary.org/obo/GO_0007263 CHEBI:84654 biolink:ChemicalSubstance (R)-4,8-dimethylnonanoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84654 chebi_ph7_3 GO:0007262 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007262 GO:0007272 biolink:BiologicalProcess ensheathment of neurons The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. go-plus.json ionic insulation of neurons by glial cells http://purl.obolibrary.org/obo/GO_0007272 GO:0007271 biolink:BiologicalProcess synaptic transmission, cholinergic The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. go-plus.json cholinergic synaptic transmission http://purl.obolibrary.org/obo/GO_0007271 CHEBI:84651 biolink:ChemicalSubstance (R)-oleoylcarnitine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84651 chebi_ph7_3 CHEBI:84650 biolink:ChemicalSubstance (5Z)-tetradecenoyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84650 chebi_ph7_3 GO:0007270 biolink:BiologicalProcess neuron-neuron synaptic transmission The process of synaptic transmission from a neuron to another neuron across a synapse. go-plus.json nerve-nerve synaptic transmission http://purl.obolibrary.org/obo/GO_0007270 GO:0046839 biolink:BiologicalProcess phospholipid dephosphorylation The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. go-plus.json http://purl.obolibrary.org/obo/GO_0046839 GO:0046838 biolink:BiologicalProcess phosphorylated carbohydrate dephosphorylation The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound based on the general formula Cx(H2O)y with a phosphate group attached to it. go-plus.json http://purl.obolibrary.org/obo/GO_0046838 GO:0046837 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046837 GO:0046836 biolink:BiologicalProcess glycolipid transport The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0046836 GO:0046835 biolink:BiologicalProcess carbohydrate phosphorylation The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y. go-plus.json http://purl.obolibrary.org/obo/GO_0046835 GO:0046834 biolink:BiologicalProcess lipid phosphorylation The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. go-plus.json http://purl.obolibrary.org/obo/GO_0046834 GO:0032203 biolink:BiologicalProcess telomere formation via telomerase A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme. go-plus.json http://purl.obolibrary.org/obo/GO_0032203 GO:0032202 biolink:BiologicalProcess telomere assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins. go-plus.json telomere formation http://purl.obolibrary.org/obo/GO_0032202 GO:0032201 biolink:BiologicalProcess telomere maintenance via semi-conservative replication The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication. go-plus.json telomeric replication fork progression|equal telomere replication|telomeric fork progression http://purl.obolibrary.org/obo/GO_0032201 GO:0032200 biolink:BiologicalProcess telomere organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins. go-plus.json organization of chromosome, telomeric region|telomere organisation|chromosome organization, telomeric|telomere organization and biogenesis http://purl.obolibrary.org/obo/GO_0032200 goslim_pombe|goslim_yeast GO:0022889 biolink:MolecularActivity serine transmembrane transporter activity Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0022889 GO:1900907 biolink:BiologicalProcess positive regulation of hexadecanal metabolic process Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process. go-plus.json up regulation of hexadecanal metabolic process|upregulation of hexadecanal metabolism|activation of hexadecanal metabolic process|activation of hexadecanal metabolism|up-regulation of hexadecanal metabolism|up-regulation of hexadecanal metabolic process|positive regulation of hexadecanal metabolism|upregulation of hexadecanal metabolic process|up regulation of hexadecanal metabolism http://purl.obolibrary.org/obo/GO_1900907 GO:1900906 biolink:BiologicalProcess negative regulation of hexadecanal metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process. go-plus.json downregulation of hexadecanal metabolic process|down regulation of hexadecanal metabolism|inhibition of hexadecanal metabolism|down-regulation of hexadecanal metabolic process|inhibition of hexadecanal metabolic process|negative regulation of hexadecanal metabolism|down-regulation of hexadecanal metabolism|downregulation of hexadecanal metabolism|down regulation of hexadecanal metabolic process http://purl.obolibrary.org/obo/GO_1900906 GO:1900909 biolink:BiologicalProcess negative regulation of olefin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process. go-plus.json down-regulation of olefin metabolic process|down-regulation of olefin metabolism|negative regulation of olefin metabolism|downregulation of olefin metabolic process|down regulation of olefin metabolic process|inhibition of olefin metabolism|inhibition of olefin metabolic process|down regulation of olefin metabolism|downregulation of olefin metabolism http://purl.obolibrary.org/obo/GO_1900909 GO:1900908 biolink:BiologicalProcess regulation of olefin metabolic process Any process that modulates the frequency, rate or extent of olefin metabolic process. go-plus.json regulation of olefin metabolism http://purl.obolibrary.org/obo/GO_1900908 GO:0140104 biolink:MolecularActivity molecular carrier activity Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location. go-plus.json http://purl.obolibrary.org/obo/GO_0140104 gocheck_do_not_annotate GO:0140103 biolink:MolecularActivity catalytic activity, acting on a glycoprotein Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein. go-plus.json http://purl.obolibrary.org/obo/GO_0140103 CHEBI:3828 biolink:ChemicalSubstance (R)-columbianetin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3828 chebi_ph7_3 GO:0140105 biolink:BiologicalProcess interleukin-10-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-10 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. go-plus.json IL-10-mediated signaling pathway|interleukin-10-mediated signalling pathway http://purl.obolibrary.org/obo/GO_0140105 GO:0140108 biolink:MolecularActivity high-affinity glucose transmembrane transporter activity Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json http://purl.obolibrary.org/obo/GO_0140108 GO:0140107 biolink:MolecularActivity high-affinity potassium ion transmembrane transporter activity Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. go-plus.json http://purl.obolibrary.org/obo/GO_0140107 UBERON:0002085 biolink:AnatomicalEntity interatrial septum A cardiac septum that divides the left and right atria of the heart. go-plus.json interatrial septal wall|atrial septum|atrium septum http://purl.obolibrary.org/obo/UBERON_0002085 UBERON:0002084 biolink:AnatomicalEntity heart left ventricle A cardiac ventricle that is in the left side of the heart. go-plus.json left ventricle|left cardiac ventricle|ventriculus sinister cordis|left ventricle of heart|cardiac left ventricle http://purl.obolibrary.org/obo/UBERON_0002084 UBERON:0002087 biolink:AnatomicalEntity atrioventricular canal The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP]. go-plus.json canalis atrioventricularis|atrio-ventricular canal|atrial canal|AV canal|AVC|ependymal canal http://purl.obolibrary.org/obo/UBERON_0002087 UBERON:0002086 biolink:AnatomicalEntity sinoatrial valve A valve at the opening of the sinus venosus into the primordial atrium[TFD,modified] go-plus.json sinoatrial valves|sinuatrial valve http://purl.obolibrary.org/obo/UBERON_0002086 UBERON:0002081 biolink:AnatomicalEntity cardiac atrium Cardiac chamber in which blood enters the heart. go-plus.json atria|cardiac atria|atrial tissue|atrium|heart atrium|atrium of heart http://purl.obolibrary.org/obo/UBERON_0002081 UBERON:0002080 biolink:AnatomicalEntity heart right ventricle A cardiac ventricle that is in the right side of the heart. go-plus.json ventriculus dexter|right ventricle of heart|right ventricle|cardiac right ventricle|right cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0002080 GO:0140102 biolink:MolecularActivity catalytic activity, acting on a rRNA Catalytic activity that acts to modify a ribosomal RNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140102 UBERON:0002082 biolink:AnatomicalEntity cardiac ventricle Cardiac chamber through which blood leaves the heart. go-plus.json heart ventricle|ventricle of heart|ventricle|lower chamber of heart http://purl.obolibrary.org/obo/UBERON_0002082 GO:0140101 biolink:MolecularActivity catalytic activity, acting on a tRNA Catalytic activity that acts to modify a tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0140101 UBERON:0002089 biolink:AnatomicalEntity thoracodorsal vein companion vein of the thoracodorsal artery, draining the apical part of the latissimus dorsi and merging with the circumflex scapular vein to form a subscapular vein go-plus.json http://purl.obolibrary.org/obo/UBERON_0002089 NCBITaxon:32443 biolink:OrganismalEntity Teleostei go-plus.json teleost fishes http://purl.obolibrary.org/obo/NCBITaxon_32443 UBERON:0002074 biolink:AnatomicalEntity hair shaft The main part of the hair which is composed of trichocytes and is divided into the cortex and medulla. go-plus.json shaft of hair|scapus pili http://purl.obolibrary.org/obo/UBERON_0002074 UBERON:0002073 biolink:AnatomicalEntity hair follicle A tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open[GO]. go-plus.json folliculus pili http://purl.obolibrary.org/obo/UBERON_0002073 UBERON:0002076 biolink:AnatomicalEntity cuticle of hair smooth and glossy outer protective cell layer of hair shaft go-plus.json hair cuticle http://purl.obolibrary.org/obo/UBERON_0002076 CHEBI:3830 biolink:ChemicalSubstance camphene go-plus.json http://purl.obolibrary.org/obo/CHEBI_3830 chebi_ph7_3 UBERON:0002075 biolink:AnatomicalEntity viscus An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. go-plus.json viscera|visceral organ|visceral tissue|visceral organ system|splanchnic tissue http://purl.obolibrary.org/obo/UBERON_0002075 UBERON:0002072 biolink:AnatomicalEntity hypodermis Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. go-plus.json hypoderm|sub-tegumental tissue|subcutaneous tissue|vertebrate hypodermis|subcutis|tela subcutanea|subtegumental tissue|superficial fascia http://purl.obolibrary.org/obo/UBERON_0002072 UBERON:0002078 biolink:AnatomicalEntity right cardiac atrium A cardiac atrium that is in the left side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve. go-plus.json cardiac right atrium|right cardiac atrium|atrium dextrum|right atrium|heart right atrium|right atrium of heart http://purl.obolibrary.org/obo/UBERON_0002078 UBERON:0002077 biolink:AnatomicalEntity cortex of hair A cortex that is part of a hair [Automatically generated definition]. go-plus.json coat/hair cortex|cortex of coat/hair|hair cortex|coat hair cortex|cortex of coat hair http://purl.obolibrary.org/obo/UBERON_0002077 UBERON:0002079 biolink:AnatomicalEntity left cardiac atrium A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve. go-plus.json left atrium of heart|heart left atrium|left cardiac atrium|left atrium|atrium sinistrum|cardiac left atrium http://purl.obolibrary.org/obo/UBERON_0002079 GO:0140125 biolink:BiologicalProcess thiamine import across plasma membrane The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140125 UBERON:0002063 biolink:AnatomicalEntity sinus venosus The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. go-plus.json inflow tract|venosus|sinus venarum|venarum sinus|sinus venosus cordis|venarum http://purl.obolibrary.org/obo/UBERON_0002063 UBERON:0002062 biolink:AnatomicalEntity endocardial cushion The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. go-plus.json endocardial cushions|cardiac cushion|atrioventricular cushion|AV cushion|endocardial cushion tissue|atrioventricular canal cushion http://purl.obolibrary.org/obo/UBERON_0002062 GO:0140122 biolink:BiologicalProcess regulation of Lewy body formation Any process that modulates the frequency, rate or extent of Lewy body formation. go-plus.json http://purl.obolibrary.org/obo/GO_0140122 GO:0140121 biolink:BiologicalProcess Lewy body formation The aggregation, arrangement and bonding together of a set of components to form a Lewy body. go-plus.json http://purl.obolibrary.org/obo/GO_0140121 GO:0140124 biolink:BiologicalProcess positive regulation of Lewy body formation Any process that activates or increases the frequency, rate or extent of Lewy body formation. go-plus.json http://purl.obolibrary.org/obo/GO_0140124 UBERON:0002061 biolink:AnatomicalEntity truncus arteriosus The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002061 UBERON:0002060 biolink:AnatomicalEntity femoral artery The femoral artery is a large artery in the muscles of the thigh. It is a continuation of external iliac artery where it enters the femoral triangle at the mid inguinal point behind the inguinal ligament. It leaves femoral triangle through apex beneath the sartorius muscle. It enters the popliteal fossa by passing through the 5th osseo-aponeurotic(adductor hiatus) opening of adductor magnus where it becomes the Popliteal Artery. [WP,unvetted]. go-plus.json arteria femoralis http://purl.obolibrary.org/obo/UBERON_0002060 GO:0140123 biolink:BiologicalProcess negative regulation of Lewy body formation Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation. go-plus.json http://purl.obolibrary.org/obo/GO_0140123 UBERON:0002067 biolink:AnatomicalEntity dermis The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. go-plus.json vertebrate dermis|corium|cutis http://purl.obolibrary.org/obo/UBERON_0002067 GO:0140115 biolink:BiologicalProcess export across plasma membrane The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json efflux http://purl.obolibrary.org/obo/GO_0140115 GO:0140114 biolink:BiologicalProcess cellular detoxification of fluoride Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. go-plus.json http://purl.obolibrary.org/obo/GO_0140114 CHEBI:11614 biolink:ChemicalSubstance 2-methylbut-2-enoyl-coenzyme A go-plus.json http://purl.obolibrary.org/obo/CHEBI_11614 GO:0140116 biolink:BiologicalProcess fluoride export across plasma membrane The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json http://purl.obolibrary.org/obo/GO_0140116 OBO:uberon/core#extends_fibers_into biolink:OntologyClass extends_fibers_into extends_fibers_into go-plus.json http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into UBERON:0002052 biolink:AnatomicalEntity adrenal gland capsule the thick capsule of dense irregular connective tissue that surrounds each adrenal gland and contains scattered elastic fibers; the capsule contains a rich plexus of blood vessels (mainly small arteries) and numerous nerve fibers; some blood vessels and nerves enter the substance of the gland in the trabeculae that extend inward from the capsule and then leave the trabeculae to enter the cortex. go-plus.json adrenal capsule|capsule of adrenal gland http://purl.obolibrary.org/obo/UBERON_0002052 UBERON:0002051 biolink:AnatomicalEntity epithelium of bronchiole An epithelium that is part of a bronchiole [Automatically generated definition]. go-plus.json epithelial tissue of bronchiole|bronchiolar epithelium|epithelial tissue of lobular bronchiole|epithelium of lobular bronchiole|bronchiole epithelial tissue|lobular bronchiole epithelium|lobular bronchiole epithelial tissue|bronchiole epithelium http://purl.obolibrary.org/obo/UBERON_0002051 GO:0140111 biolink:MolecularActivity [choline trimethylamine-lyase]-activating enzyme activity Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM). MetaCyc:RXN-16470 go-plus.json http://purl.obolibrary.org/obo/GO_0140111 GO:0140110 biolink:MolecularActivity transcription regulator activity A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons. go-plus.json http://purl.obolibrary.org/obo/GO_0140110 gocheck_do_not_annotate|goslim_plant|goslim_flybase_ribbon GO:0140113 biolink:BiologicalProcess extracellular microvesicle biogenesis The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding. go-plus.json extracellular microvesicle assembly http://purl.obolibrary.org/obo/GO_0140113 UBERON:0002050 biolink:AnatomicalEntity embryonic structure Anatomical structure that is part of an embryo. go-plus.json embryonale Struktur|embryonic structures|embryonic anatomical structure|developing structure|developing embryonic structure http://purl.obolibrary.org/obo/UBERON_0002050 GO:0140112 biolink:BiologicalProcess extracellular vesicle biogenesis The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content. go-plus.json extracellular vesicle assembly http://purl.obolibrary.org/obo/GO_0140112 UBERON:0002059 biolink:AnatomicalEntity submandibular ganglion the ganglion associated with the lingual nerve that provides postsynaptic fibers to the submandibular and sublingual glands go-plus.json maxillary ganglion|submaxillary ganglion|ganglion submandibulare|Blandin`s ganglion|mandibular ganglion|lingual ganglion http://purl.obolibrary.org/obo/UBERON_0002059 UBERON:0002056 biolink:AnatomicalEntity inferior suprarenal artery Each renal artery gives off some small inferior suprarenal branches to the suprarenal gland, the ureter, and the surrounding cellular tissue and muscles. [WP,unvetted]. go-plus.json arteria suprarenalis inferior http://purl.obolibrary.org/obo/UBERON_0002056 UBERON:0002057 biolink:AnatomicalEntity phrenic artery An artery that supplies the diaphragm go-plus.json http://purl.obolibrary.org/obo/UBERON_0002057 GO:0032195 biolink:CellularComponent post-lysosomal vacuole A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis. go-plus.json post-lysosome http://purl.obolibrary.org/obo/GO_0032195 GO:0032194 biolink:BiologicalProcess ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate. go-plus.json http://purl.obolibrary.org/obo/GO_0032194 GO:0032193 biolink:BiologicalProcess ubiquinone biosynthetic process via 2-polyprenylphenol The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol. go-plus.json http://purl.obolibrary.org/obo/GO_0032193 GO:0032192 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032192 GO:0032191 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032191 GO:0032190 biolink:MolecularActivity acrosin binding Binding to acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities. go-plus.json acrosin light chain binding|acrosin heavy chain binding http://purl.obolibrary.org/obo/GO_0032190 OBO:uberon/core#sexually_homologous_to biolink:OntologyClass sexually_homologous_to sexually_homologous_to go-plus.json http://purl.obolibrary.org/obo/uberon/core#sexually_homologous_to GO:0032199 biolink:BiologicalProcess reverse transcription involved in RNA-mediated transposition The synthesis of DNA from an RNA transposon intermediate. go-plus.json reverse transcription during retrotransposition http://purl.obolibrary.org/obo/GO_0032199 GO:0032198 biolink:BiologicalProcess MITE transposition Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs). go-plus.json Class III transposition http://purl.obolibrary.org/obo/GO_0032198 GO:0032197 biolink:BiologicalProcess transposition, RNA-mediated Any process involved in a type of transpositional recombination which occurs via an RNA intermediate. Wikipedia:Transposon##Class_I:_Retrotransposons go-plus.json Tf transposition|Ty3 element transposition|Ty2 element transposition|Ty1 element transposition|retrotransposon transposition|Ty element transposition|RNA-mediated transposition|retrotransposition|Class I transposition http://purl.obolibrary.org/obo/GO_0032197 GO:0032196 biolink:BiologicalProcess transposition Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. Wikipedia:Transposon go-plus.json http://purl.obolibrary.org/obo/GO_0032196 goslim_pir|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_candida|goslim_yeast GO:0032184 biolink:MolecularActivity SUMO polymer binding Binding to a polymer of the small ubiquitin-like protein SUMO. go-plus.json Smt3 polymer binding http://purl.obolibrary.org/obo/GO_0032184 GO:0032183 biolink:MolecularActivity SUMO binding Binding to the small ubiquitin-like protein SUMO. go-plus.json Smt3 monomer binding|Smt3 binding http://purl.obolibrary.org/obo/GO_0032183 GO:0032182 biolink:MolecularActivity ubiquitin-like protein binding Binding to a small conjugating protein such as ubiquitin or a ubiquitin-like protein. go-plus.json small conjugating protein binding http://purl.obolibrary.org/obo/GO_0032182 goslim_chembl|goslim_yeast|goslim_generic GO:0032181 biolink:MolecularActivity dinucleotide repeat insertion binding Binding to a double-stranded DNA region containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats. go-plus.json http://purl.obolibrary.org/obo/GO_0032181 GO:0032180 biolink:BiologicalProcess ubiquinone biosynthetic process from tyrosine The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate. go-plus.json http://purl.obolibrary.org/obo/GO_0032180 GO:0032189 biolink:BiologicalProcess maintenance of actomyosin contractile ring localization Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere. go-plus.json maintenance of contractile ring localization involved in cytokinesis during cell cycle|maintenance of contractile ring localisation involved in cell cycle cytokinesis|maintenance of contractile ring localization involved in cell cycle cytokinesis|cytokinetic ring anchoring http://purl.obolibrary.org/obo/GO_0032189 GO:0032188 biolink:BiologicalProcess establishment of actomyosin contractile ring localization The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis. go-plus.json establishment of contractile ring localisation involved in cell cycle cytokinesis|establishment of contractile ring localization involved in cytokinesis during cell cycle|establishment of contractile ring localization involved in cell cycle cytokinesis|actomyosin ring positioning|cytokinesis site selection by contractile ring positioning|contractile ring positioning http://purl.obolibrary.org/obo/GO_0032188 GO:0032187 biolink:BiologicalProcess actomyosin contractile ring localization The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle. go-plus.json contractile ring localisation involved in cell cycle cytokinesis|contractile ring localization involved in cell cycle cytokinesis http://purl.obolibrary.org/obo/GO_0032187 GO:0032186 biolink:BiologicalProcess cellular bud neck septin ring organization Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck. go-plus.json cellular bud neck septin ring organisation http://purl.obolibrary.org/obo/GO_0032186 GO:0032185 biolink:BiologicalProcess septin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins. go-plus.json septin cytoskeleton organisation|septin cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/GO_0032185 GO:0032173 biolink:CellularComponent septin collar A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell. go-plus.json septin hourglass http://purl.obolibrary.org/obo/GO_0032173 GO:0032172 biolink:CellularComponent germ tube septin ring A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0032172 GO:0032171 biolink:CellularComponent germ tube septin cap A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol. go-plus.json http://purl.obolibrary.org/obo/GO_0032171 GO:0032170 biolink:CellularComponent pseudohyphal septin ring A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0032170 CHEBI:60601 biolink:ChemicalSubstance delta-opioid agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_60601 GO:0032179 biolink:CellularComponent germ tube The slender tubular outgrowth first produced by most spores in germination. Wikipedia:Germ_tube go-plus.json http://purl.obolibrary.org/obo/GO_0032179 goslim_pir CHEBI:60606 biolink:ChemicalSubstance opioid receptor agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_60606 GO:0032178 biolink:CellularComponent medial membrane band A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum. go-plus.json sterol-rich membrane band http://purl.obolibrary.org/obo/GO_0032178 GO:0032177 biolink:CellularComponent cellular bud neck split septin rings Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated. go-plus.json http://purl.obolibrary.org/obo/GO_0032177 GO:0032176 biolink:CellularComponent split septin rings A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well. go-plus.json http://purl.obolibrary.org/obo/GO_0032176 GO:0032175 biolink:CellularComponent mating projection septin ring A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip. go-plus.json http://purl.obolibrary.org/obo/GO_0032175 GO:0032174 biolink:CellularComponent cellular bud neck septin collar A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck. go-plus.json http://purl.obolibrary.org/obo/GO_0032174 UBERON:0002090 biolink:AnatomicalEntity postcranial axial skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. go-plus.json axial skeleton|post-cranial axial skeleton http://purl.obolibrary.org/obo/UBERON_0002090 GO:0032162 biolink:CellularComponent mating projection septin band A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection). go-plus.json http://purl.obolibrary.org/obo/GO_0032162 GO:0032161 biolink:CellularComponent cleavage apparatus septin structure Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis. go-plus.json http://purl.obolibrary.org/obo/GO_0032161 UBERON:0002095 biolink:AnatomicalEntity mesentery Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon. go-plus.json mesentery (generic)|generic mesentery http://purl.obolibrary.org/obo/UBERON_0002095 GO:0032160 biolink:CellularComponent septin filament array Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans. go-plus.json septin bar http://purl.obolibrary.org/obo/GO_0032160 UBERON:0002097 biolink:AnatomicalEntity skin of body The organ covering the body that consists of the dermis and epidermis. go-plus.json integument|integumental organ|pelt|skin|skin organ|entire skin|entire integument http://purl.obolibrary.org/obo/UBERON_0002097 UBERON:0002092 biolink:AnatomicalEntity brain dura mater The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer. go-plus.json dura mater encephali|dura mater of brain|cranial dura mater|dura mater cranialis http://purl.obolibrary.org/obo/UBERON_0002092 UBERON:0002091 biolink:AnatomicalEntity appendicular skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. go-plus.json entire appendicular skeleton|appendicular skeleton|skeleton appendiculare|paired fin skeleton http://purl.obolibrary.org/obo/UBERON_0002091 UBERON:0002094 biolink:AnatomicalEntity interventricular septum Cardiac septum which separates the right ventricle from the left ventricle.[FMA] go-plus.json heart ventricular septum|intraventricular septum|septum inferius|s. interventriculare cordis|interventriculare cordis|ventricle septum|septum membranaceum|heart interventricular septum|interventricular septum of heart|ventricular septum http://purl.obolibrary.org/obo/UBERON_0002094 UBERON:0002093 biolink:AnatomicalEntity spinal dura mater A dura mater that is part of a spinal cord [Automatically generated definition]. go-plus.json dura mater of neuraxis of spinal cord|spinal cord dura mater|dura mater of spinal cord|spinal cord dura mater of neuraxis http://purl.obolibrary.org/obo/UBERON_0002093 CHEBI:60615 biolink:ChemicalSubstance N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue go-plus.json http://purl.obolibrary.org/obo/CHEBI_60615 chebi_ph7_3 GO:0032169 biolink:CellularComponent prospore septin ring A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0032169 GO:0032168 biolink:CellularComponent hyphal septin ring A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0032168 GO:0032167 biolink:CellularComponent obsolete septin patch OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis. go-plus.json septin patch http://purl.obolibrary.org/obo/GO_0032167 GO:0032166 biolink:CellularComponent chlamydospore septin filament array Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation. go-plus.json http://purl.obolibrary.org/obo/GO_0032166 UBERON:0002099 biolink:AnatomicalEntity cardiac septum The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles. go-plus.json heart septum|cardiac septa|spiral septa|heart septa|septum of heart http://purl.obolibrary.org/obo/UBERON_0002099 GO:0032165 biolink:CellularComponent prospore septin filament array Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation. go-plus.json http://purl.obolibrary.org/obo/GO_0032165 GO:0032164 biolink:CellularComponent hyphal septin cap A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol. go-plus.json http://purl.obolibrary.org/obo/GO_0032164 GO:0032163 biolink:CellularComponent hyphal septin band A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously. go-plus.json http://purl.obolibrary.org/obo/GO_0032163 CHEBI:21010 biolink:ChemicalSubstance D-glucosyl-D-mannose go-plus.json http://purl.obolibrary.org/obo/CHEBI_21010 GO:1900877 biolink:BiologicalProcess nonadec-1-ene biosynthetic process The chemical reactions and pathways resulting in the formation of nonadec-1-ene. go-plus.json nonadec-1-ene formation|nonadec-1-ene biosynthesis|nonadec-1-ene anabolism|nonadec-1-ene synthesis http://purl.obolibrary.org/obo/GO_1900877 GO:1900876 biolink:BiologicalProcess nonadec-1-ene metabolic process The chemical reactions and pathways involving nonadec-1-ene. go-plus.json nonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900876 GO:1900879 biolink:BiologicalProcess (Z)-nonadeca-1,14-diene biosynthetic process The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene. go-plus.json (Z)-nonadeca-1,14-diene anabolism|(Z)-nonadeca-1,14-diene synthesis|(Z)-nonadeca-1,14-diene biosynthesis|(Z)-nonadeca-1,14-diene formation http://purl.obolibrary.org/obo/GO_1900879 GO:1900878 biolink:BiologicalProcess (Z)-nonadeca-1,14-diene metabolic process The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene. go-plus.json (Z)-nonadeca-1,14-diene metabolism http://purl.obolibrary.org/obo/GO_1900878 GO:1900873 biolink:BiologicalProcess pentadec-1-ene biosynthetic process The chemical reactions and pathways resulting in the formation of pentadec-1-ene. go-plus.json pentadec-1-ene anabolism|pentadec-1-ene synthesis|pentadec-1-ene formation|pentadec-1-ene biosynthesis http://purl.obolibrary.org/obo/GO_1900873 GO:1900872 biolink:BiologicalProcess pentadec-1-ene metabolic process The chemical reactions and pathways involving pentadec-1-ene. go-plus.json pentadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900872 GO:1900875 biolink:BiologicalProcess heptadec-1-ene biosynthetic process The chemical reactions and pathways resulting in the formation of heptadec-1-ene. go-plus.json heptadec-1-ene anabolism|heptadec-1-ene synthesis|heptadec-1-ene formation|heptadec-1-ene biosynthesis http://purl.obolibrary.org/obo/GO_1900875 GO:1900874 biolink:BiologicalProcess heptadec-1-ene metabolic process The chemical reactions and pathways involving heptadec-1-ene. go-plus.json heptadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900874 GO:1900871 biolink:BiologicalProcess chloroplast mRNA modification The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically. go-plus.json chloroplast mRNA editing|mRNA editing in chloroplast http://purl.obolibrary.org/obo/GO_1900871 GO:1900870 biolink:BiologicalProcess tatiopterin biosynthetic process The chemical reactions and pathways resulting in the formation of tatiopterin. go-plus.json tatiopterin biosynthesis|tatiopterin anabolism|tatiopterin synthesis|tatiopterin formation http://purl.obolibrary.org/obo/GO_1900870 CHEBI:11684 biolink:ChemicalSubstance 3,3',5'-triiodo-L-thyronine go-plus.json http://purl.obolibrary.org/obo/CHEBI_11684 UBERON:2000238 biolink:AnatomicalEntity olfactory tract linking bulb to ipsilateral ventral telencephalon go-plus.json http://purl.obolibrary.org/obo/UBERON_2000238 GO:0071769 biolink:BiologicalProcess mycolate cell wall layer assembly The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer. MetaCyc:PWY-6397 go-plus.json mycolate cell wall layer biogenesis http://purl.obolibrary.org/obo/GO_0071769 GO:0071768 biolink:BiologicalProcess mycolic acid biosynthetic process The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain. MetaCyc:PWYG-321 go-plus.json mycolic acid formation|mycolic acid biosynthesis|mycolate biosynthetic process|mycolic acid anabolism|mycolic acid synthesis http://purl.obolibrary.org/obo/GO_0071768 GO:0071767 biolink:BiologicalProcess mycolic acid metabolic process The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain. go-plus.json mycolate metabolic process|mycolic acid metabolism http://purl.obolibrary.org/obo/GO_0071767 UBERON:0002005 biolink:AnatomicalEntity enteric nervous system The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation[GO]. go-plus.json enteric PNS|PNS - enteric http://purl.obolibrary.org/obo/UBERON_0002005 GO:0071766 biolink:BiologicalProcess Actinobacterium-type cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface. go-plus.json http://purl.obolibrary.org/obo/GO_0071766 GO:0071765 biolink:BiologicalProcess nuclear inner membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane. go-plus.json nuclear inner membrane organization and biogenesis|nuclear inner membrane organisation http://purl.obolibrary.org/obo/GO_0071765 UBERON:0002007 biolink:AnatomicalEntity medulla of lymph node The mdeullary portion of the lymph node, which contains large blood vessels, sinuses and medullary cords that contain antibody-secreting plasma cells. go-plus.json medulla nodi lymphoidei|lymph node medulla http://purl.obolibrary.org/obo/UBERON_0002007 GO:0071764 biolink:BiologicalProcess nuclear outer membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. go-plus.json nuclear outer membrane organisation|nuclear outer membrane organization and biogenesis http://purl.obolibrary.org/obo/GO_0071764 UBERON:0002006 biolink:AnatomicalEntity cortex of lymph node Peripheral portion of the lymph node, underneath the capsule[WP]. go-plus.json lymph node cortex|cortex nodi lymphoidei http://purl.obolibrary.org/obo/UBERON_0002006 GO:0071763 biolink:BiologicalProcess nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. go-plus.json nuclear membrane organization and biogenesis|nuclear membrane organisation http://purl.obolibrary.org/obo/GO_0071763 UBERON:0002001 biolink:AnatomicalEntity joint of rib Any joint that connects a rib to another structure (or another rib). Examples: costochondral, costovertebral, interchondral, sternocostal joints. go-plus.json rib joint http://purl.obolibrary.org/obo/UBERON_0002001 GO:0071762 biolink:CellularComponent heavy chain immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains. go-plus.json IgNAR antibody|HCab|Ig NAR immunoglobulin complex|IgNAR immunoglobulin complex http://purl.obolibrary.org/obo/GO_0071762 GO:0071761 biolink:CellularComponent IgZ immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish. go-plus.json IgT immunoglobulin complex|IgT antibody|IgZ antibody http://purl.obolibrary.org/obo/GO_0071761 GO:0071760 biolink:CellularComponent IgY immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0071760 GO:1900888 biolink:BiologicalProcess negative regulation of pentadecane biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process. go-plus.json down regulation of pentadecane biosynthetic process|downregulation of pentadecane biosynthesis|inhibition of pentadecane biosynthetic process|inhibition of pentadecane biosynthesis|down regulation of pentadecane anabolism|inhibition of pentadecane formation|down regulation of pentadecane biosynthesis|downregulation of pentadecane anabolism|down regulation of pentadecane synthesis|down regulation of pentadecane formation|downregulation of pentadecane synthesis|downregulation of pentadecane formation|negative regulation of pentadecane anabolism|down-regulation of pentadecane anabolism|down-regulation of pentadecane biosynthetic process|negative regulation of pentadecane synthesis|down-regulation of pentadecane synthesis|inhibition of pentadecane synthesis|negative regulation of pentadecane formation|down-regulation of pentadecane formation|down-regulation of pentadecane biosynthesis|negative regulation of pentadecane biosynthesis|inhibition of pentadecane anabolism|downregulation of pentadecane biosynthetic process http://purl.obolibrary.org/obo/GO_1900888 GO:1900887 biolink:BiologicalProcess regulation of pentadecane biosynthetic process Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process. go-plus.json regulation of pentadecane anabolism|regulation of pentadecane synthesis|regulation of pentadecane formation|regulation of pentadecane biosynthesis http://purl.obolibrary.org/obo/GO_1900887 GO:1900889 biolink:BiologicalProcess positive regulation of pentadecane biosynthetic process Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process. go-plus.json upregulation of pentadecane anabolism|upregulation of pentadecane biosynthetic process|upregulation of pentadecane synthesis|activation of pentadecane anabolism|upregulation of pentadecane formation|upregulation of pentadecane biosynthesis|up regulation of pentadecane anabolism|activation of pentadecane synthesis|activation of pentadecane biosynthetic process|up-regulation of pentadecane biosynthetic process|positive regulation of pentadecane anabolism|activation of pentadecane biosynthesis|activation of pentadecane formation|up regulation of pentadecane synthesis|positive regulation of pentadecane synthesis|up regulation of pentadecane formation|up-regulation of pentadecane biosynthesis|positive regulation of pentadecane formation|up-regulation of pentadecane anabolism|up regulation of pentadecane biosynthetic process|up-regulation of pentadecane synthesis|positive regulation of pentadecane biosynthesis|up regulation of pentadecane biosynthesis|up-regulation of pentadecane formation http://purl.obolibrary.org/obo/GO_1900889 GO:1900884 biolink:BiologicalProcess regulation of tridecane biosynthetic process Any process that modulates the frequency, rate or extent of tridecane biosynthetic process. go-plus.json regulation of tridecane formation|regulation of tridecane biosynthesis|regulation of tridecane anabolism|regulation of tridecane synthesis http://purl.obolibrary.org/obo/GO_1900884 GO:1900883 biolink:BiologicalProcess 17-methylnonadec-1-ene biosynthetic process The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene. go-plus.json 17-methylnonadec-1-ene anabolism|17-methylnonadec-1-ene biosynthesis|17-methylnonadec-1-ene synthesis|17-methylnonadec-1-ene formation http://purl.obolibrary.org/obo/GO_1900883 GO:1900886 biolink:BiologicalProcess positive regulation of tridecane biosynthetic process Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process. go-plus.json activation of tridecane anabolism|positive regulation of tridecane anabolism|up regulation of tridecane synthesis|activation of tridecane synthesis|positive regulation of tridecane synthesis|up regulation of tridecane formation|upregulation of tridecane biosynthesis|upregulation of tridecane biosynthetic process|activation of tridecane formation|positive regulation of tridecane formation|up-regulation of tridecane anabolism|up-regulation of tridecane synthesis|up-regulation of tridecane biosynthesis|up-regulation of tridecane biosynthetic process|activation of tridecane biosynthesis|activation of tridecane biosynthetic process|up-regulation of tridecane formation|upregulation of tridecane anabolism|upregulation of tridecane synthesis|positive regulation of tridecane biosynthesis|upregulation of tridecane formation|up regulation of tridecane biosynthesis|up regulation of tridecane biosynthetic process|up regulation of tridecane anabolism http://purl.obolibrary.org/obo/GO_1900886 GO:1900885 biolink:BiologicalProcess negative regulation of tridecane biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process. go-plus.json downregulation of tridecane synthesis|downregulation of tridecane biosynthetic process|downregulation of tridecane biosynthesis|downregulation of tridecane formation|down regulation of tridecane biosynthesis|down regulation of tridecane biosynthetic process|negative regulation of tridecane anabolism|down-regulation of tridecane anabolism|inhibition of tridecane biosynthetic process|inhibition of tridecane biosynthesis|negative regulation of tridecane synthesis|down-regulation of tridecane synthesis|negative regulation of tridecane formation|down-regulation of tridecane formation|inhibition of tridecane anabolism|inhibition of tridecane synthesis|inhibition of tridecane formation|down-regulation of tridecane biosynthetic process|down-regulation of tridecane biosynthesis|negative regulation of tridecane biosynthesis|down regulation of tridecane anabolism|downregulation of tridecane anabolism|down regulation of tridecane synthesis|down regulation of tridecane formation http://purl.obolibrary.org/obo/GO_1900885 GO:1900880 biolink:BiologicalProcess 18-methylnonadec-1-ene metabolic process The chemical reactions and pathways involving 18-methylnonadec-1-ene. go-plus.json 18-methylnonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900880 GO:1900882 biolink:BiologicalProcess 17-methylnonadec-1-ene metabolic process The chemical reactions and pathways involving 17-methylnonadec-1-ene. go-plus.json 17-methylnonadec-1-ene metabolism http://purl.obolibrary.org/obo/GO_1900882 GO:1900881 biolink:BiologicalProcess 18-methylnonadec-1-ene biosynthetic process The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene. go-plus.json 18-methylnonadec-1-ene anabolism|18-methylnonadec-1-ene biosynthesis|18-methylnonadec-1-ene synthesis|18-methylnonadec-1-ene formation http://purl.obolibrary.org/obo/GO_1900881 CHEBI:35663 biolink:ChemicalSubstance carane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35663 chebi_ph7_3 CHEBI:35662 biolink:ChemicalSubstance terpenoid fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35662 CHEBI:35664 biolink:ChemicalSubstance EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35664 CHEBI:35666 biolink:ChemicalSubstance thiopurine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35666 UBERON:2000228 biolink:AnatomicalEntity lateral line primordium go-plus.json lateral line primordia|llp http://purl.obolibrary.org/obo/UBERON_2000228 GO:0071759 biolink:CellularComponent IgX immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0071759 GO:0071758 biolink:CellularComponent IgW immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0071758 GO:0071757 biolink:CellularComponent hexameric IgM immunoglobulin complex A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide. go-plus.json hexameric IgM antibody http://purl.obolibrary.org/obo/GO_0071757 GO:0071756 biolink:CellularComponent pentameric IgM immunoglobulin complex A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide. go-plus.json pentameric IgM antibody http://purl.obolibrary.org/obo/GO_0071756 GO:0071755 biolink:CellularComponent IgM B cell receptor complex An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. go-plus.json membrane-bound IgM|surface IgM http://purl.obolibrary.org/obo/GO_0071755 GO:0071754 biolink:CellularComponent IgM immunoglobulin complex, circulating A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph. go-plus.json IgM antibody http://purl.obolibrary.org/obo/GO_0071754 GO:0071753 biolink:CellularComponent IgM immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json http://purl.obolibrary.org/obo/GO_0071753 GO:0071752 biolink:CellularComponent secretory dimeric IgA immunoglobulin complex A dimeric form of secretory IgA immunoglobulin complex. go-plus.json secretory dimeric IgA1 antibody|secretory dimeric IgA antibody http://purl.obolibrary.org/obo/GO_0071752 GO:0071751 biolink:CellularComponent secretory IgA immunoglobulin complex A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component. go-plus.json secretory IgA antibody|sIgA antibody|sIgA1 antibody http://purl.obolibrary.org/obo/GO_0071751 CHEBI:35661 biolink:ChemicalSubstance car-3-ene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35661 chebi_ph7_3 GO:0071750 biolink:CellularComponent dimeric IgA immunoglobulin complex A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. go-plus.json dimeric IgA antibody|dimeric IgA1 antibody http://purl.obolibrary.org/obo/GO_0071750 CHEBI:35660 biolink:ChemicalSubstance HIV protease inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35660 GO:0071781 biolink:CellularComponent endoplasmic reticulum cisternal network A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells. go-plus.json ER cisternal network http://purl.obolibrary.org/obo/GO_0071781 GO:0071780 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071780 GO:1900899 biolink:BiologicalProcess regulation of heptadecane metabolic process Any process that modulates the frequency, rate or extent of heptadecane metabolic process. go-plus.json regulation of heptadecane metabolism http://purl.obolibrary.org/obo/GO_1900899 GO:1900898 biolink:BiologicalProcess positive regulation of heptadecane biosynthetic process Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process. go-plus.json positive regulation of heptadecane anabolism|up regulation of heptadecane biosynthetic process|activation of heptadecane formation|up regulation of heptadecane synthesis|positive regulation of heptadecane biosynthesis|positive regulation of heptadecane synthesis|up regulation of heptadecane formation|up regulation of heptadecane biosynthesis|positive regulation of heptadecane formation|upregulation of heptadecane biosynthetic process|up-regulation of heptadecane anabolism|up-regulation of heptadecane synthesis|upregulation of heptadecane biosynthesis|up-regulation of heptadecane formation|up-regulation of heptadecane biosynthetic process|upregulation of heptadecane anabolism|activation of heptadecane biosynthetic process|activation of heptadecane biosynthesis|upregulation of heptadecane synthesis|up-regulation of heptadecane biosynthesis|upregulation of heptadecane formation|activation of heptadecane anabolism|up regulation of heptadecane anabolism|activation of heptadecane synthesis http://purl.obolibrary.org/obo/GO_1900898 GO:1900895 biolink:BiologicalProcess positive regulation of tridecane metabolic process Any process that activates or increases the frequency, rate or extent of tridecane metabolic process. go-plus.json activation of tridecane metabolism|up regulation of tridecane metabolic process|activation of tridecane metabolic process|up-regulation of tridecane metabolism|up-regulation of tridecane metabolic process|positive regulation of tridecane metabolism|up regulation of tridecane metabolism|upregulation of tridecane metabolic process|upregulation of tridecane metabolism http://purl.obolibrary.org/obo/GO_1900895 GO:1900894 biolink:BiologicalProcess negative regulation of tridecane metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process. go-plus.json down-regulation of tridecane metabolic process|negative regulation of tridecane metabolism|down-regulation of tridecane metabolism|inhibition of tridecane metabolic process|downregulation of tridecane metabolism|inhibition of tridecane metabolism|down regulation of tridecane metabolism|down regulation of tridecane metabolic process|downregulation of tridecane metabolic process http://purl.obolibrary.org/obo/GO_1900894 GO:1900897 biolink:BiologicalProcess negative regulation of heptadecane biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process. go-plus.json negative regulation of heptadecane biosynthesis|down-regulation of heptadecane biosynthesis|downregulation of heptadecane formation|downregulation of heptadecane biosynthetic process|down-regulation of heptadecane anabolism|negative regulation of heptadecane anabolism|inhibition of heptadecane anabolism|down regulation of heptadecane biosynthetic process|down-regulation of heptadecane synthesis|negative regulation of heptadecane synthesis|downregulation of heptadecane biosynthesis|inhibition of heptadecane synthesis|inhibition of heptadecane biosynthetic process|inhibition of heptadecane biosynthesis|down-regulation of heptadecane formation|negative regulation of heptadecane formation|down regulation of heptadecane biosynthesis|inhibition of heptadecane formation|down regulation of heptadecane anabolism|downregulation of heptadecane anabolism|down regulation of heptadecane synthesis|down-regulation of heptadecane biosynthetic process|down regulation of heptadecane formation|downregulation of heptadecane synthesis http://purl.obolibrary.org/obo/GO_1900897 GO:1900896 biolink:BiologicalProcess regulation of heptadecane biosynthetic process Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process. go-plus.json regulation of heptadecane biosynthesis|regulation of heptadecane anabolism|regulation of heptadecane synthesis|regulation of heptadecane formation http://purl.obolibrary.org/obo/GO_1900896 GO:1900891 biolink:BiologicalProcess negative regulation of pentadecane metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process. go-plus.json downregulation of pentadecane metabolic process|negative regulation of pentadecane metabolism|down-regulation of pentadecane metabolism|down-regulation of pentadecane metabolic process|downregulation of pentadecane metabolism|inhibition of pentadecane metabolism|inhibition of pentadecane metabolic process|down regulation of pentadecane metabolism|down regulation of pentadecane metabolic process http://purl.obolibrary.org/obo/GO_1900891 GO:1900890 biolink:BiologicalProcess regulation of pentadecane metabolic process Any process that modulates the frequency, rate or extent of pentadecane metabolic process. go-plus.json regulation of pentadecane metabolism http://purl.obolibrary.org/obo/GO_1900890 GO:1900893 biolink:BiologicalProcess regulation of tridecane metabolic process Any process that modulates the frequency, rate or extent of tridecane metabolic process. go-plus.json regulation of tridecane metabolism http://purl.obolibrary.org/obo/GO_1900893 GO:1900892 biolink:BiologicalProcess positive regulation of pentadecane metabolic process Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process. go-plus.json up-regulation of pentadecane metabolism|up regulation of pentadecane metabolic process|activation of pentadecane metabolic process|positive regulation of pentadecane metabolism|up regulation of pentadecane metabolism|up-regulation of pentadecane metabolic process|upregulation of pentadecane metabolism|activation of pentadecane metabolism|upregulation of pentadecane metabolic process http://purl.obolibrary.org/obo/GO_1900892 GO:0071789 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071789 GO:0071788 biolink:BiologicalProcess endoplasmic reticulum tubular network maintenance The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. go-plus.json ER tubular network maintenance http://purl.obolibrary.org/obo/GO_0071788 GO:0071787 biolink:BiologicalProcess endoplasmic reticulum tubular network formation The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. go-plus.json ER tubular network formation|endoplasmic reticulum tubular network assembly|ER tubular network assembly http://purl.obolibrary.org/obo/GO_0071787 GO:0071786 biolink:BiologicalProcess endoplasmic reticulum tubular network organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. go-plus.json ER tubular network organisation|endoplasmic reticulum tubular network organisation|ER tubular network organization http://purl.obolibrary.org/obo/GO_0071786 GO:0071785 biolink:BiologicalProcess endoplasmic reticulum cisternal network maintenance The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. go-plus.json ER cisternal network maintenance http://purl.obolibrary.org/obo/GO_0071785 GO:0071784 biolink:BiologicalProcess endoplasmic reticulum cisternal network assembly The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. go-plus.json endoplasmic reticulum cisternal network formation|ER cisternal network formation|ER cisternal network assembly http://purl.obolibrary.org/obo/GO_0071784 GO:0071783 biolink:BiologicalProcess endoplasmic reticulum cisternal network organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. go-plus.json ER cisternal network organisation|endoplasmic reticulum cisternal network organisation|ER cisternal network organization http://purl.obolibrary.org/obo/GO_0071783 GO:0071782 biolink:CellularComponent endoplasmic reticulum tubular network A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section. go-plus.json ER tubular network http://purl.obolibrary.org/obo/GO_0071782 GO:0071770 biolink:BiologicalProcess DIM/DIP cell wall layer assembly The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall. go-plus.json DIM cell wall layer assembly|DIM/DIP cell wall layer biogenesis|PDIM cell wall layer assembly http://purl.obolibrary.org/obo/GO_0071770 CHEBI:21006 biolink:ChemicalSubstance D-glucose monophosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21006 CHEBI:21005 biolink:ChemicalSubstance D-glucose bisphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21005 CHEBI:35649 biolink:ChemicalSubstance morphinan go-plus.json http://purl.obolibrary.org/obo/CHEBI_35649 UBERON:0016612 biolink:AnatomicalEntity auditory hillocks, pharyngeal arch 2 derived A collection of protruberances derived from pharyngeal arch 2 that develop into the concha, antihelix and antitragus. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016612 UBERON:0016611 biolink:AnatomicalEntity auditory hillocks, pharyngeal arch 1 derived A collection of protruberances derived from pharyngeal arch 1 that develop into the tragus, crus of the helix, and helix. go-plus.json http://purl.obolibrary.org/obo/UBERON_0016611 GO:0140195 biolink:BiologicalProcess positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process. go-plus.json http://purl.obolibrary.org/obo/GO_0140195 CHEBI:35640 biolink:ChemicalSubstance adrenergic uptake inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35640 GO:0140194 biolink:BiologicalProcess negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process. go-plus.json http://purl.obolibrary.org/obo/GO_0140194 CHEBI:35643 biolink:ChemicalSubstance aporphine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35643 GO:0140196 biolink:BiologicalProcess positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process. go-plus.json http://purl.obolibrary.org/obo/GO_0140196 GO:0140199 biolink:BiologicalProcess negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process. go-plus.json http://purl.obolibrary.org/obo/GO_0140199 GO:0071779 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071779 GO:0071778 biolink:CellularComponent obsolete WINAC complex OBSOLETE. A SWI/SNF-type complex that directly interacts with the vitamin D receptor (VDR) through the Williams syndrome transcription factor (WSTF), and mediates the recruitment of unliganded VDR to VDR target sites in promoters. The WINAC complex contains at least 13 subunits, including WSTF, several SWI/SNF components, and DNA replication-related factors. go-plus.json WINAC complex http://purl.obolibrary.org/obo/GO_0071778 CHEBI:21008 biolink:ChemicalSubstance glucose phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_21008 GO:0071777 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071777 GO:0071776 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071776 GO:0071775 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071775 GO:0071774 biolink:BiologicalProcess response to fibroblast growth factor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus. go-plus.json response to fibroblast growth factor stimulus|response to FGF stimulus http://purl.obolibrary.org/obo/GO_0071774 GO:0071773 biolink:BiologicalProcess cellular response to BMP stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. go-plus.json cellular response to bone morphogenetic protein stimulus http://purl.obolibrary.org/obo/GO_0071773 GO:0140193 biolink:BiologicalProcess regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process. go-plus.json http://purl.obolibrary.org/obo/GO_0140193 GO:0071772 biolink:BiologicalProcess response to BMP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. go-plus.json response to BMP stimulus|response to bone morphogenetic protein stimulus http://purl.obolibrary.org/obo/GO_0071772 GO:0071771 biolink:MolecularActivity aldehyde decarbonylase activity Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO. go-plus.json decarbonylase activity http://purl.obolibrary.org/obo/GO_0071771 CHEBI:3892 biolink:ChemicalSubstance corticotropin go-plus.json http://purl.obolibrary.org/obo/CHEBI_3892 GO:0140192 biolink:BiologicalProcess regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process. go-plus.json http://purl.obolibrary.org/obo/GO_0140192 CHEBI:35616 biolink:ChemicalSubstance trans-anethole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35616 chebi_ph7_3 GO:0140147 biolink:BiologicalProcess zinc ion export from vacuole The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140147 CHEBI:35615 biolink:ChemicalSubstance tropane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35615 CHEBI:35618 biolink:ChemicalSubstance aromatic ether go-plus.json http://purl.obolibrary.org/obo/CHEBI_35618 CHEBI:35617 biolink:ChemicalSubstance flavouring agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35617 CHEBI:35619 biolink:ChemicalSubstance L-alpha-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35619 OBO:GOCHE_24020 biolink:OntologyClass substance with fat-soluble vitamin role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24020 3_STAR GO:0140140 biolink:BiologicalProcess mitochondrial guanine nucleotide transmembrane transport The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0140140 CHEBI:11641 biolink:ChemicalSubstance 2-oxopent-4-enoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11641 chebi_ph7_3 UBERON:0002040 biolink:AnatomicalEntity bronchial artery A systemic artery that supplies the lung with with oxygenated blood. go-plus.json rami bronchiales partis thoracicae aortae|bronchial arterial tree|arteriae bronchiales http://purl.obolibrary.org/obo/UBERON_0002040 UBERON:0002043 biolink:AnatomicalEntity dorsal raphe nucleus A large raphe nucleus extending from the anterior part of the pons through the mesencephalon; its neurons are serotoninergic[NIF]. The dorsal raphe nucleus is a part of the raphe nucleus and consists of rostral and caudal subdivisions. The rostral aspect of the dorsal raphe is further divided into interfascicular, ventral, ventrolateral and dorsal subnuclei. The projections of the dorsal raphe have been found to vary topographically, and thus the subnuclei differ in their projections. An increased number of cells in the lateral aspects of the dorsal raphe is characteristic of humans and other primates. [WP,unvetted]. go-plus.json DR|nucleus dorsalis raphes|nucleus raphes posterior|nucleus raphes dorsalis|nucleus raphes posterior|dorsal nucleus of the raphe|dorsal raphe|DRN|dorsal raphé|cell group b7|posterior raphe nucleus|inferior raphe nucleus|posterior raphe nucleus|nucleus raphe dorsalis|nucleus raphe posterior|dorsal nucleus raphe http://purl.obolibrary.org/obo/UBERON_0002043 GO:0140142 biolink:MolecularActivity nucleocytoplasmic carrier activity Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein. go-plus.json miRNA transporter activity|nucleocytoplasmic importin/exportin activity|pre-miRNA transporter activity http://purl.obolibrary.org/obo/GO_0140142 gocheck_do_not_annotate CHEBI:35610 biolink:ChemicalSubstance antineoplastic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35610 UBERON:0002042 biolink:AnatomicalEntity lymphatic vessel endothelium An endothelium that is part of a lymphatic vessel [Automatically generated definition]. go-plus.json endothelium of lymph vessel|lymphatic endothelium|lymph vessel endothelium|endothelium of lymphatic vessel|lymphatic vessel endothelium http://purl.obolibrary.org/obo/UBERON_0002042 GO:0140141 biolink:BiologicalProcess mitochondrial potassium ion transmembrane transport The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0140141 GO:0140146 biolink:BiologicalProcess calcium ion import into vacuole The directed movement of calcium cations into the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140146 GO:0140145 biolink:BiologicalProcess copper ion export from vacuole The directed movement of copper ions out of the vacuole across the vacuolar membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0140145 UBERON:0002049 biolink:AnatomicalEntity vasculature An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. go-plus.json vascular network http://purl.obolibrary.org/obo/UBERON_0002049 OBO:GOCHE_24028 biolink:OntologyClass substance with iron(3+) chelator role go-plus.json http://purl.obolibrary.org/obo/GOCHE_24028 1_STAR UBERON:0002048 biolink:AnatomicalEntity lung Respiration organ that develops as an outpocketing of the esophagus. go-plus.json pulmo http://purl.obolibrary.org/obo/UBERON_0002048 UBERON:0002047 biolink:AnatomicalEntity pontine raphe nucleus The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. go-plus.json raphe pontis nucleus|raphe (mediana pontina)|nucleus raphe pontis|raphe pontis|raphe of pons|nucleus raphes pontis http://purl.obolibrary.org/obo/UBERON_0002047 UBERON:0002046 biolink:AnatomicalEntity thyroid gland A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]. go-plus.json thyroid|glandula thyroidea http://purl.obolibrary.org/obo/UBERON_0002046 GO:0071792 biolink:BiologicalProcess bacillithiol metabolic process The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species. go-plus.json bacillithiol metabolism http://purl.obolibrary.org/obo/GO_0071792 GO:0071791 biolink:MolecularActivity chemokine (C-C motif) ligand 5 binding Binding to chemokine (C-C motif) ligand 5. go-plus.json RANTES binding|Regulated upon Activation, Normal T-cell Expressed, and Secreted binding|CCL5 binding http://purl.obolibrary.org/obo/GO_0071791 GO:0071790 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071790 CHEBI:35627 biolink:ChemicalSubstance beta-lactam go-plus.json http://purl.obolibrary.org/obo/CHEBI_35627 chebi_ph7_3 UBERON:0002030 biolink:AnatomicalEntity nipple Projection of skin containing the outlets for 15-20 lactiferous ducts arranged cylindrically around the tip. go-plus.json papillary part of breast|papilla of breast|thele|teat|thelium|papilla mammaria|papilla mammae http://purl.obolibrary.org/obo/UBERON_0002030 GO:0140131 biolink:BiologicalProcess positive regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis. go-plus.json http://purl.obolibrary.org/obo/GO_0140131 CHEBI:35621 biolink:ChemicalSubstance alpha-aminobutyric acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35621 UBERON:0002031 biolink:AnatomicalEntity epithelium of bronchus An epithelium that is part of a bronchus [Automatically generated definition]. go-plus.json bronchial trunk epithelium|bronchi epithelium|bronchial epithelium|epithelial tissue of bronchus|epithelium of bronchi|epithelium of bronchial trunk|epithelial tissue of bronchi|epithelial tissue of bronchial trunk|bronchi epithelial tissue|bronchial trunk epithelial tissue|bronchus epithelial tissue|bronchus epithelium http://purl.obolibrary.org/obo/UBERON_0002031 CHEBI:35620 biolink:ChemicalSubstance vasodilator agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35620 GO:0140133 biolink:BiologicalProcess suppression by symbiont of host cytokine production Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. go-plus.json negative regulation by symbiont of host cytokine production|suppression by symbiont of host cytokine secretion http://purl.obolibrary.org/obo/GO_0140133 CHEBI:35623 biolink:ChemicalSubstance anticonvulsant go-plus.json http://purl.obolibrary.org/obo/CHEBI_35623 GO:0140132 biolink:MolecularActivity iron-sulfur cluster carrier activity Binding to an iron-sulfur cluster and delivering it to an acceptor molecule. go-plus.json http://purl.obolibrary.org/obo/GO_0140132 CHEBI:35622 biolink:ChemicalSubstance thiazolidines go-plus.json http://purl.obolibrary.org/obo/CHEBI_35622 GO:0140135 biolink:MolecularActivity mechanosensitive cation channel activity Enables the transmembrane transfer of a cation by a channel that opens in response to a mechanical stress. go-plus.json mechanically-gated cation channel activity http://purl.obolibrary.org/obo/GO_0140135 CHEBI:35625 biolink:ChemicalSubstance EC 3.5.2.6 (beta-lactamase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35625 CHEBI:35624 biolink:ChemicalSubstance azaspiro compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35624 UBERON:0002038 biolink:AnatomicalEntity substantia nigra Predominantly gray matter midbrain structure lying dorsal to the crus cerebri and ventral to the midbrain tegmentum. It is divided into a dorsal, cellularly compact region known as the pars compacta and a more ventrally located, containing more loosely packed cells, the pars reticulata. The most lateral region of the reticulata is identified as the pars lateralis (MM). go-plus.json nucleus pigmentosus subthalamo-peduncularis|SN|Soemmering's substance|substancia nigra|substantia nigra (Soemmerringi)|nucleus of basis pedunculi http://purl.obolibrary.org/obo/UBERON_0002038 UBERON:0002037 biolink:AnatomicalEntity cerebellum Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]. go-plus.json corpus cerebelli|parencephalon|infratentorial region|epencephalon-1 http://purl.obolibrary.org/obo/UBERON_0002037 GO:0071799 biolink:BiologicalProcess cellular response to prostaglandin D stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0071799 GO:0071798 biolink:BiologicalProcess response to prostaglandin D Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus. go-plus.json response to prostaglandin D stimulus http://purl.obolibrary.org/obo/GO_0071798 GO:0071797 biolink:CellularComponent LUBAC complex A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex. go-plus.json http://purl.obolibrary.org/obo/GO_0071797 GO:0071796 biolink:MolecularActivity K6-linked polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0071796 GO:0071795 biolink:MolecularActivity K11-linked polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0071795 UBERON:0002033 biolink:AnatomicalEntity arrector muscle of hair A tiny smooth muscle that connects the hair follicle with the dermis. go-plus.json pilomotor muscle|arrector pili muscle|arrector pilli muscle|arrector pilli|erector pili|arrector pilorum|erectores pilorum|arrector pili smooth muscle|arectores pilorum|arrector pili|arrector pilorum muscle of hair http://purl.obolibrary.org/obo/UBERON_0002033 GO:0071794 biolink:MolecularActivity CAP-Gly domain binding Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets. go-plus.json http://purl.obolibrary.org/obo/GO_0071794 UBERON:0002036 biolink:AnatomicalEntity striated muscle tissue Muscle tissue that contains fibers that are divided by transverse bands into striations. go-plus.json striated muscle http://purl.obolibrary.org/obo/UBERON_0002036 GO:0071793 biolink:BiologicalProcess bacillithiol biosynthetic process The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species. go-plus.json bacillithiol anabolism|bacillithiol synthesis|bacillithiol formation|bacillithiol biosynthesis http://purl.obolibrary.org/obo/GO_0071793 UBERON:0002019 biolink:AnatomicalEntity accessory XI nerve A cranial nerve that originates from neurons in the medulla and in the cervical spinal cord. go-plus.json nervus accessorius [XI]|eleventh cranial nerve|accessory nerve [XI]|Willis' nerve|spinal accessory nerve tree|pars spinalis nervus accessorius|cranial nerve XI|CN-XI|spinal part of accessory nerve|accessory XI nerve|spinal accessory nerve|cervical accessory nerve|radix spinalis nervus accessorius|accessory spinal nerve|accessory XI|accessory nerve http://purl.obolibrary.org/obo/UBERON_0002019 GO:0140161 biolink:MolecularActivity monocarboxylate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in). go-plus.json http://purl.obolibrary.org/obo/GO_0140161 GO:0140164 biolink:MolecularActivity Golgi transport complex binding Binding to a Golgi transport complex, a multisubunit tethering complex of the CATCHR family. go-plus.json COG complex binding http://purl.obolibrary.org/obo/GO_0140164 UBERON:0002020 biolink:AnatomicalEntity gray matter A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. go-plus.json grey matter|neuronal grey matter|grey matter of neuraxis|gray matter|gray matter of neuraxis|substantia grisea|grey substance|grisea|gray mater http://purl.obolibrary.org/obo/UBERON_0002020 UBERON:0002029 biolink:AnatomicalEntity epithelium of gall bladder The simple columnar epithelial lining of the gall bladder. go-plus.json gall bladder epithelial tissue|biliary epithelium|gallbladder epithelium|epithelium of gallbladder|epithelial tissue of gallbladder|gallbladder epithelial tissue|epithelial tissue of gall bladder|gall bladder epithelium http://purl.obolibrary.org/obo/UBERON_0002029 UBERON:0002028 biolink:AnatomicalEntity hindbrain The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. go-plus.json rhombencephalon http://purl.obolibrary.org/obo/UBERON_0002028 GO:0140160 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140160 UBERON:0002008 biolink:AnatomicalEntity cardiac nerve plexus A plexus of nerves situated at the base of the heart that innervate the heart. go-plus.json autonomic plexus of heart|plexus cardiacus|heart autonomic nerve plexus|cardiac plexus|autonomic nerve plexus of heart|heart autonomic plexus http://purl.obolibrary.org/obo/UBERON_0002008 GO:0140159 biolink:BiologicalProcess borate export across plasma membrane The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json http://purl.obolibrary.org/obo/GO_0140159 CHEBI:35605 biolink:ChemicalSubstance carbon oxoacid go-plus.json http://purl.obolibrary.org/obo/CHEBI_35605 CHEBI:35604 biolink:ChemicalSubstance carbon oxoanion go-plus.json http://purl.obolibrary.org/obo/CHEBI_35604 CHEBI:35608 biolink:ChemicalSubstance EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35608 CHEBI:35601 biolink:ChemicalSubstance 2H-chromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35601 chebi_ph7_3 CHEBI:11656 biolink:ChemicalSubstance 2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_11656 CHEBI:35603 biolink:ChemicalSubstance 4H-chromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35603 chebi_ph7_3 GO:0140157 biolink:BiologicalProcess ammonium import across plasma membrane The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140157 CHEBI:35602 biolink:ChemicalSubstance chromene go-plus.json http://purl.obolibrary.org/obo/CHEBI_35602 UBERON:0002016 biolink:AnatomicalEntity pulmonary vein Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]. go-plus.json venae pulmonales|pulmonary venous tree organ part http://purl.obolibrary.org/obo/UBERON_0002016 SO:0001217 biolink:SequenceFeature protein_coding_gene A gene that codes for an RNA that can be translated into a protein. go-plus.json protein coding gene http://purl.obolibrary.org/obo/SO_0001217 Alliance_of_Genome_Resources UBERON:0002015 biolink:AnatomicalEntity kidney capsule the tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage go-plus.json capsula fibrosa renis|renal capsule|capsule of kidney|fibrous capsule of kidney http://purl.obolibrary.org/obo/UBERON_0002015 UBERON:0002017 biolink:AnatomicalEntity portal vein A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]. go-plus.json portal venous tree organ part http://purl.obolibrary.org/obo/UBERON_0002017 UBERON:0002012 biolink:AnatomicalEntity pulmonary artery An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. go-plus.json arteria pulmonalis|truncus pulmonalis|pulmonary arterial tree organ part|pulmonary arterial tree|pulmonary arterial subtree http://purl.obolibrary.org/obo/UBERON_0002012 UBERON:0002011 biolink:AnatomicalEntity thoracodorsal artery The thoracodorsal artery is a branch of the subscapular artery. It travels inferiorly with the thoracodorsal nerve and supplies the latissimus dorsi. [WP,unvetted]. go-plus.json arteria thoracodorsalis http://purl.obolibrary.org/obo/UBERON_0002011 GO:0032319 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032319 GO:0032318 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032318 GO:0032317 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032317 GO:0032316 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032316 GO:0032315 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032315 GO:0007359 biolink:BiologicalProcess posterior abdomen determination The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes. go-plus.json http://purl.obolibrary.org/obo/GO_0007359 GO:0007358 biolink:BiologicalProcess establishment of central gap gene boundaries Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel. go-plus.json http://purl.obolibrary.org/obo/GO_0007358 GO:0032314 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032314 GO:0046965 biolink:MolecularActivity retinoid X receptor binding Binding to a retinoid X receptor. go-plus.json RXR binding http://purl.obolibrary.org/obo/GO_0046965 GO:0007357 biolink:BiologicalProcess obsolete positive regulation of central gap gene transcription OBSOLETE. The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products. go-plus.json up regulation of central gap gene transcription|upregulation of central gap gene transcription|stimulation of central gap gene transcription|activation of central gap gene transcription|up-regulation of central gap gene transcription|activation of central gap gene http://purl.obolibrary.org/obo/GO_0007357 OBO:GOCHE_38867 biolink:OntologyClass substance with anaesthetic role go-plus.json http://purl.obolibrary.org/obo/GOCHE_38867 3_STAR CHEBI:142853 biolink:ChemicalSubstance (2R)-glufosinate go-plus.json http://purl.obolibrary.org/obo/CHEBI_142853 GO:0007356 biolink:BiologicalProcess thorax and anterior abdomen determination Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product. go-plus.json http://purl.obolibrary.org/obo/GO_0007356 GO:0046964 biolink:MolecularActivity 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other. Reactome:R-HSA-741449 go-plus.json 3'-phosphoadenosine 5'-phosphosulphate transporter activity|adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity|PAPS transporter activity http://purl.obolibrary.org/obo/GO_0046964 CHEBI:142852 biolink:ChemicalSubstance glufosinate-P go-plus.json http://purl.obolibrary.org/obo/CHEBI_142852 CHEBI:84548 biolink:ChemicalSubstance 2-demethylmenaquinol-11 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84548 chebi_ph7_3 GO:0046963 biolink:BiologicalProcess 3'-phosphoadenosine 5'-phosphosulfate transport The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json PAPS transport|adenosine 3'-phosphate 5'-phosphosulfate transport|3'-phosphoadenosine 5'-phosphosulphate transport http://purl.obolibrary.org/obo/GO_0046963 GO:0007355 biolink:BiologicalProcess anterior region determination Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product. go-plus.json http://purl.obolibrary.org/obo/GO_0007355 CHEBI:142851 biolink:ChemicalSubstance 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_142851 GO:0046962 biolink:MolecularActivity sodium-transporting ATPase activity, rotational mechanism Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out), by a rotational mechanism. RHEA:58156|RHEA:58157|MetaCyc:3.6.3.15-RXN|EC:7.2.2.1 go-plus.json vacuolar-type Na+-translocating ATPase|sodium-translocating F-type ATPase activity|sodium-transporting two-sector ATPase activity|Na+-translocating F1Fo-ATPase|ATP phosphohydrolase (Na+-transporting) activity|vacuolar-type Na+-ATPase|Na(+)-transporting two-sector ATPase activity|ATP synthase, sodium ion specific activity|sodium transporting ATPase activity, rotational mechanism|Na+-transporting two-sector ATPase|sodium-translocating V-type ATPase activity|Na(+)-translocating ATPase activity|Na+-translocating ATPase activity http://purl.obolibrary.org/obo/GO_0046962 CHEBI:84547 biolink:ChemicalSubstance menaquinol-11 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84547 chebi_ph7_3 GO:0007354 biolink:BiologicalProcess zygotic determination of anterior/posterior axis, embryo The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade. go-plus.json http://purl.obolibrary.org/obo/GO_0007354 GO:0046961 biolink:MolecularActivity proton-transporting ATPase activity, rotational mechanism Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism. MetaCyc:ATPSYN-RXN|RHEA:57721|EC:7.1.2.2 go-plus.json FoF1-ATPase|hydrogen ion translocating F-type ATPase activity|hydrogen ion transporting ATPase activity, rotational mechanism|F0F1-ATPase|F1-ATPase|F(1)-ATPase activity|mitochondrial ATPase activity|hydrogen ion transporting two-sector ATPase activity|F(o)F(1)-ATPase activity|F(0)F(1)-ATPase activity|hydrogen ion translocating V-type ATPase activity|H(+)-transporting ATP synthase activity|H+-transporting ATPase activity|chloroplast ATPase activity|ATP phosphohydrolase (H+-transporting) activity|ATP synthase activity|hydrogen ion translocating A-type ATPase activity http://purl.obolibrary.org/obo/GO_0046961 CHEBI:84546 biolink:ChemicalSubstance 2-demethylmenaquinol-10 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84546 chebi_ph7_3 GO:0007353 biolink:BiologicalProcess obsolete ventral/lateral system OBSOLETE. (Was not defined before being made obsolete). go-plus.json ventral/lateral system http://purl.obolibrary.org/obo/GO_0007353 GO:0046960 biolink:BiologicalProcess sensitization An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched. Wikipedia:Sensitization go-plus.json http://purl.obolibrary.org/obo/GO_0046960 GO:0007352 biolink:BiologicalProcess zygotic specification of dorsal/ventral axis The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote. go-plus.json zygotic determination of dorsal-ventral axis|zygotic determination of dorsal/ventral axis|zygotic determination of dorsoventral axis http://purl.obolibrary.org/obo/GO_0007352 CHEBI:60584 biolink:ChemicalSubstance bicozamycin go-plus.json http://purl.obolibrary.org/obo/CHEBI_60584 chebi_ph7_3 CHEBI:84544 biolink:ChemicalSubstance menaquinol-10 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84544 chebi_ph7_3 GO:0007351 biolink:BiologicalProcess tripartite regional subdivision Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions. go-plus.json http://purl.obolibrary.org/obo/GO_0007351 GO:0071919 biolink:BiologicalProcess G-quadruplex DNA formation A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature. go-plus.json G quartet DNA formation|G quadruplex DNA formation|G-quartet DNA formation http://purl.obolibrary.org/obo/GO_0071919 GO:0007350 biolink:BiologicalProcess blastoderm segmentation The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0007350 CHEBI:84543 biolink:ChemicalSubstance 1-oleoyl-2-linoleyl-sn-glycero-3-phosphoethanolamine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84543 GO:0071929 biolink:BiologicalProcess alpha-tubulin acetylation The addition of an acetyl group to the lysine 40 residue of alpha-tubulin. go-plus.json http://purl.obolibrary.org/obo/GO_0071929 GO:0007360 biolink:BiologicalProcess obsolete positive regulation of posterior gap gene transcription OBSOLETE. The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene. go-plus.json upregulation of posterior gap gene transcription|stimulation of posterior gap gene transcription|up-regulation of posterior gap gene transcription|activation of posterior gap gene transcription|activation of posterior gap gene|knirps activation|up regulation of posterior gap gene transcription http://purl.obolibrary.org/obo/GO_0007360 CHEBI:84542 biolink:ChemicalSubstance 2-demethylmenaquinol-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84542 chebi_ph7_3 CHEBI:166828 biolink:ChemicalSubstance Saccharolipids go-plus.json http://purl.obolibrary.org/obo/CHEBI_166828 GO:0071928 biolink:BiologicalProcess tyramine signaling pathway The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor. go-plus.json tyramine signalling pathway http://purl.obolibrary.org/obo/GO_0071928 CHEBI:84541 biolink:ChemicalSubstance menaquinol-9 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84541 chebi_ph7_3 CHEBI:60585 biolink:ChemicalSubstance 3,6-diamino-10-methylacridinium go-plus.json http://purl.obolibrary.org/obo/CHEBI_60585 chebi_ph7_3 CHEBI:84540 biolink:ChemicalSubstance dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84540 chebi_ph7_3 CHEBI:142859 biolink:ChemicalSubstance glufosinate-P zwitterion(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142859 chebi_ph7_3 GO:0071927 biolink:BiologicalProcess octopamine signaling pathway The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor. go-plus.json octopamine signalling pathway http://purl.obolibrary.org/obo/GO_0071927 GO:0071926 biolink:BiologicalProcess endocannabinoid signaling pathway The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol. go-plus.json endocannabinoid signalling pathway http://purl.obolibrary.org/obo/GO_0071926 CHEBI:142858 biolink:ChemicalSubstance (2R)-glufosinate zwitterion(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142858 chebi_ph7_3 CHEBI:166829 biolink:ChemicalSubstance ochratoxin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_166829 chebi_ph7_3 GO:0046969 biolink:MolecularActivity NAD-dependent histone deacetylase activity (H3-K9 specific) Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein. Reactome:R-HSA-9604829 go-plus.json http://purl.obolibrary.org/obo/GO_0046969 GO:0071925 biolink:BiologicalProcess thymic stromal lymphopoietin production The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json TSLP production http://purl.obolibrary.org/obo/GO_0071925 gocheck_do_not_annotate GO:0071924 biolink:BiologicalProcess chemokine (C-C motif) ligand 22 production The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json CCL22 production|CCL-22 production|C-C motif chemokine 22 production http://purl.obolibrary.org/obo/GO_0071924 gocheck_do_not_annotate CHEBI:142856 biolink:ChemicalSubstance glufosinate-P zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142856 GO:0046968 biolink:BiologicalProcess peptide antigen transport The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. go-plus.json http://purl.obolibrary.org/obo/GO_0046968 GO:0071923 biolink:BiologicalProcess negative regulation of cohesin loading Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin. go-plus.json negative regulation of cohesin localisation to chromatin|negative regulation of cohesin localization to chromatin|negative regulation of cohesin association with chromatin http://purl.obolibrary.org/obo/GO_0071923 GO:0046967 biolink:BiologicalProcess cytosol to endoplasmic reticulum transport The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell. go-plus.json cytosol to ER transport|cytosol to endoplasmic reticulum transport http://purl.obolibrary.org/obo/GO_0046967 GO:0071922 biolink:BiologicalProcess regulation of cohesin loading Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin. go-plus.json regulation of cohesin association with chromatin|regulation of cohesin localisation to chromatin|regulation of cohesin localization to chromatin http://purl.obolibrary.org/obo/GO_0071922 GO:0046966 biolink:MolecularActivity thyroid hormone receptor binding Binding to a thyroid hormone receptor. go-plus.json ligand-dependent thyroid hormone receptor interactor activity http://purl.obolibrary.org/obo/GO_0046966 CHEBI:142854 biolink:ChemicalSubstance (2R)-glufosinate zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_142854 GO:0071921 biolink:BiologicalProcess cohesin loading The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA. go-plus.json cohesin localisation to chromatin|cohesin localization to chromatin|cohesin association with chromatin http://purl.obolibrary.org/obo/GO_0071921 GO:0032313 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032313 GO:0071920 biolink:CellularComponent cleavage body A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing. go-plus.json http://purl.obolibrary.org/obo/GO_0071920 GO:0032312 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032312 GO:0032311 biolink:CellularComponent angiogenin-PRI complex A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis. go-plus.json angiogenin-placental ribonuclease inhibitor complex http://purl.obolibrary.org/obo/GO_0032311 GO:0032310 biolink:BiologicalProcess prostaglandin secretion The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue. go-plus.json prostacyclin secretion http://purl.obolibrary.org/obo/GO_0032310 GO:1900804 biolink:BiologicalProcess brevianamide F catabolic process The chemical reactions and pathways resulting in the breakdown of brevianamide F. go-plus.json cyclo-L-Trp-L-Pro breakdown|L-prolyl-L-tryptophan anhydride degradation|tryptophan-proline diketopiperazine catabolic process|cyclo-L-Trp-L-Pro catabolic process|L-prolyl-L-tryptophan anhydride breakdown|L-tryptophyl-L-proline cyclic anhydride degradation|cyclo-(Trp-Pro) catabolism|L-prolyl-L-tryptophan anhydride catabolic process|L-tryptophyl-L-proline cyclic anhydride breakdown|cyclo-(Trp-Pro) degradation|L-tryptophyl-L-proline cyclic anhydride catabolism|brevianamide F catabolism|L-tryptophyl-L-proline cyclic anhydride catabolic process|cyclo-(Trp-Pro) breakdown|L-prolyl-L-tryptophan anhydride catabolism|cyclo-L-tryptophanyl-L-proline degradation|cyclo-(Trp-Pro) catabolic process|cyclo-L-Trp-L-Pro catabolism|tryptophan-proline diketopiperazine catabolism|cyclo-L-tryptophanyl-L-proline breakdown|tryptophan-proline diketopiperazine degradation|brevianamide F degradation|cyclo-L-Trp-L-Pro degradation|cyclo-L-tryptophanyl-L-proline catabolism|cyclo-L-tryptophanyl-L-proline catabolic process|brevianamide F breakdown|tryptophan-proline diketopiperazine breakdown http://purl.obolibrary.org/obo/GO_1900804 GO:1900803 biolink:BiologicalProcess brevianamide F metabolic process The chemical reactions and pathways involving brevianamide F. go-plus.json L-prolyl-L-tryptophan anhydride metabolic process|cyclo-L-tryptophanyl-L-proline metabolism|L-tryptophyl-L-proline cyclic anhydride metabolic process|cyclo-(Trp-Pro) metabolism|L-tryptophyl-L-proline cyclic anhydride metabolism|brevianamide F metabolism|cyclo-L-tryptophanyl-L-proline metabolic process|L-prolyl-L-tryptophan anhydride metabolism|tryptophan-proline diketopiperazine metabolic process|cyclo-L-Trp-L-Pro metabolic process|cyclo-L-Trp-L-Pro metabolism|tryptophan-proline diketopiperazine metabolism http://purl.obolibrary.org/obo/GO_1900803 GO:0032309 biolink:BiologicalProcess icosanoid secretion The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue. go-plus.json eicosanoid secretion http://purl.obolibrary.org/obo/GO_0032309 GO:0032308 biolink:BiologicalProcess positive regulation of prostaglandin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell. go-plus.json up-regulation of prostaglandin secretion|positive regulation of prostacyclin secretion|upregulation of prostaglandin secretion|up regulation of prostaglandin secretion|activation of prostaglandin secretion|stimulation of prostaglandin secretion http://purl.obolibrary.org/obo/GO_0032308 GO:1900806 biolink:BiologicalProcess ergot alkaloid catabolic process The chemical reactions and pathways resulting in the breakdown of ergot alkaloid. go-plus.json ergot alkaloids breakdown|ergot alkaloid catabolism|ergot alkaloids catabolic process|ergot alkaloid degradation|ergot alkaloid breakdown|ergot alkaloids catabolism|ergot alkaloids degradation http://purl.obolibrary.org/obo/GO_1900806 GO:0032307 biolink:BiologicalProcess negative regulation of prostaglandin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell. go-plus.json inhibition of prostaglandin secretion|negative regulation of prostacyclin secretion|down regulation of prostaglandin secretion|downregulation of prostaglandin secretion|down-regulation of prostaglandin secretion http://purl.obolibrary.org/obo/GO_0032307 GO:1900805 biolink:BiologicalProcess brevianamide F biosynthetic process The chemical reactions and pathways resulting in the formation of brevianamide F. go-plus.json cyclo-L-tryptophanyl-L-proline biosynthesis|cyclo-(Trp-Pro) formation|cyclo-L-tryptophanyl-L-proline biosynthetic process|cyclo-L-tryptophanyl-L-proline anabolism|cyclo-L-tryptophanyl-L-proline synthesis|tryptophan-proline diketopiperazine anabolism|brevianamide F anabolism|cyclo-L-Trp-L-Pro anabolism|cyclo-L-tryptophanyl-L-proline formation|cyclo-(Trp-Pro) biosynthesis|cyclo-(Trp-Pro) biosynthetic process|tryptophan-proline diketopiperazine synthesis|brevianamide F synthesis|cyclo-L-Trp-L-Pro synthesis|C16H17N3O2 anabolism|L-prolyl-L-tryptophan anhydride anabolism|tryptophan-proline diketopiperazine formation|brevianamide F formation|L-tryptophyl-L-proline cyclic anhydride biosynthetic process|cyclo-L-Trp-L-Pro formation|L-tryptophyl-L-proline cyclic anhydride biosynthesis|C16H17N3O2 synthesis|brevianamide F biosynthesis|L-prolyl-L-tryptophan anhydride synthesis|L-tryptophyl-L-proline cyclic anhydride anabolism|C16H17N3O2 formation|L-prolyl-L-tryptophan anhydride formation|L-prolyl-L-tryptophan anhydride biosynthesis|C16H17N3O2 biosynthetic process|C16H17N3O2 biosynthesis|L-prolyl-L-tryptophan anhydride biosynthetic process|L-tryptophyl-L-proline cyclic anhydride synthesis|cyclo-(Trp-Pro) anabolism|cyclo-L-Trp-L-Pro biosynthetic process|cyclo-L-Trp-L-Pro biosynthesis|L-tryptophyl-L-proline cyclic anhydride formation|tryptophan-proline diketopiperazine biosynthetic process|tryptophan-proline diketopiperazine biosynthesis|cyclo-(Trp-Pro) synthesis http://purl.obolibrary.org/obo/GO_1900805 GO:1900800 biolink:BiologicalProcess cspyrone B1 metabolic process The chemical reactions and pathways involving cspyrone B1. go-plus.json cspyrone B1 metabolism http://purl.obolibrary.org/obo/GO_1900800 GO:0032306 biolink:BiologicalProcess regulation of prostaglandin secretion Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell. go-plus.json regulation of prostacyclin secretion http://purl.obolibrary.org/obo/GO_0032306 GO:0032305 biolink:BiologicalProcess positive regulation of icosanoid secretion Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell. go-plus.json up-regulation of icosanoid secretion|positive regulation of eicosanoid secretion|upregulation of icosanoid secretion|up regulation of icosanoid secretion|activation of icosanoid secretion|stimulation of icosanoid secretion http://purl.obolibrary.org/obo/GO_0032305 GO:0032304 biolink:BiologicalProcess negative regulation of icosanoid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell. go-plus.json inhibition of icosanoid secretion|negative regulation of eicosanoid secretion|down regulation of icosanoid secretion|downregulation of icosanoid secretion|down-regulation of icosanoid secretion http://purl.obolibrary.org/obo/GO_0032304 GO:1900802 biolink:BiologicalProcess cspyrone B1 biosynthetic process The chemical reactions and pathways resulting in the formation of cspyrone B1. go-plus.json cspyrone B1 biosynthesis|cspyrone B1 anabolism|cspyrone B1 synthesis|cspyrone B1 formation http://purl.obolibrary.org/obo/GO_1900802 GO:1900801 biolink:BiologicalProcess cspyrone B1 catabolic process The chemical reactions and pathways resulting in the breakdown of cspyrone B1. go-plus.json cspyrone B1 catabolism|cspyrone B1 degradation|cspyrone B1 breakdown http://purl.obolibrary.org/obo/GO_1900801 GO:0007369 biolink:BiologicalProcess gastrulation A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. Wikipedia:Gastrulation go-plus.json http://purl.obolibrary.org/obo/GO_0007369 goslim_drosophila GO:0032303 biolink:BiologicalProcess regulation of icosanoid secretion Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell. go-plus.json regulation of eicosanoid secretion http://purl.obolibrary.org/obo/GO_0032303 GO:0007368 biolink:BiologicalProcess determination of left/right symmetry The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. go-plus.json determination of left/right asymmetry http://purl.obolibrary.org/obo/GO_0007368 GO:0046976 biolink:MolecularActivity histone methyltransferase activity (H3-K27 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein. Reactome:R-HSA-3240295 go-plus.json histone methylase activity (H3-K27 specific)|histone lysine N-methyltransferase activity (H3-K27 specific) http://purl.obolibrary.org/obo/GO_0046976 CHEBI:142842 biolink:ChemicalSubstance andrastin A go-plus.json http://purl.obolibrary.org/obo/CHEBI_142842 CHEBI:166831 biolink:ChemicalSubstance copper chelator go-plus.json http://purl.obolibrary.org/obo/CHEBI_166831 GO:0046975 biolink:MolecularActivity histone methyltransferase activity (H3-K36 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein. go-plus.json histone methylase activity (H3-K36 specific)|histone lysine N-methyltransferase activity (H3-K36 specific) http://purl.obolibrary.org/obo/GO_0046975 GO:0007367 biolink:BiologicalProcess segment polarity determination Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products. go-plus.json http://purl.obolibrary.org/obo/GO_0007367 GO:0046974 biolink:MolecularActivity histone methyltransferase activity (H3-K9 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein. Reactome:R-HSA-427527|Reactome:R-HSA-427336 go-plus.json histone lysine N-methyltransferase activity (H3-K9 specific)|histone methylase activity (H3-K9 specific) http://purl.obolibrary.org/obo/GO_0046974 GO:0007366 biolink:BiologicalProcess periodic partitioning by pair rule gene Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities. go-plus.json http://purl.obolibrary.org/obo/GO_0007366 CHEBI:84559 biolink:ChemicalSubstance 2,4-dinitroanisole go-plus.json http://purl.obolibrary.org/obo/CHEBI_84559 chebi_ph7_3 GO:0046973 biolink:MolecularActivity obsolete histone lysine N-methyltransferase activity (H3-K24 specific) OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein. go-plus.json histone lysine N-methyltransferase activity (H3-K24 specific) http://purl.obolibrary.org/obo/GO_0046973 GO:0007365 biolink:BiologicalProcess periodic partitioning The regionalization process that divides the spatial regions of an embryo into serially repeated regions. go-plus.json http://purl.obolibrary.org/obo/GO_0007365 GO:0007364 biolink:BiologicalProcess establishment of terminal gap gene boundary Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes. go-plus.json http://purl.obolibrary.org/obo/GO_0007364 GO:0046972 biolink:MolecularActivity histone acetyltransferase activity (H4-K16 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4. go-plus.json histone lysine acetyltransferase activity (H4-K16 specific) http://purl.obolibrary.org/obo/GO_0046972 GO:0007363 biolink:BiologicalProcess obsolete positive regulation of terminal gap gene transcription OBSOLETE. The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes. go-plus.json up regulation of terminal gap gene transcription|activation of terminal gap gene transcription|activation of terminal gap gene|stimulation of terminal gap gene transcription|up-regulation of terminal gap gene transcription|upregulation of terminal gap gene transcription http://purl.obolibrary.org/obo/GO_0007363 GO:0046971 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046971 GO:0071909 biolink:BiologicalProcess determination of stomach left/right asymmetry Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0071909 GO:0046970 biolink:MolecularActivity NAD-dependent histone deacetylase activity (H4-K16 specific) Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein. go-plus.json http://purl.obolibrary.org/obo/GO_0046970 GO:0007362 biolink:BiologicalProcess terminal region determination Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products. go-plus.json http://purl.obolibrary.org/obo/GO_0007362 GO:0071908 biolink:BiologicalProcess determination of intestine left/right asymmetry Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0071908 CHEBI:84554 biolink:ChemicalSubstance 3,5-dihydroxyphenylacetyl-CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84554 chebi_ph7_3 GO:0007361 biolink:BiologicalProcess establishment of posterior gap gene boundaries Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps. go-plus.json http://purl.obolibrary.org/obo/GO_0007361 GO:0007371 biolink:BiologicalProcess ventral midline determination The regionalization process in which the area where the ventral midline will form is specified. go-plus.json determination of posterior border of ventral midline|determination of anterior border of ventral midline http://purl.obolibrary.org/obo/GO_0007371 GO:0071918 biolink:BiologicalProcess urea transmembrane transport The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. go-plus.json urea membrane transport http://purl.obolibrary.org/obo/GO_0071918 CHEBI:84553 biolink:ChemicalSubstance 2-demethylmenaquinol-13 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84553 chebi_ph7_3 GO:0007370 biolink:BiologicalProcess ventral furrow formation Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0007370 GO:0071917 biolink:MolecularActivity triose-phosphate transmembrane transporter activity Enables the transfer of a triose phosphate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0071917 CHEBI:84552 biolink:ChemicalSubstance menaquinol-13 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84552 chebi_ph7_3 CHEBI:60599 biolink:ChemicalSubstance mu-opioid agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_60599 GO:0071916 biolink:MolecularActivity dipeptide transmembrane transporter activity Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond. go-plus.json dipeptide transporter activity http://purl.obolibrary.org/obo/GO_0071916 CHEBI:84551 biolink:ChemicalSubstance 2-demethylmenaquinol-12 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84551 chebi_ph7_3 CHEBI:59573 biolink:ChemicalSubstance (1->2)-beta-D-mannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_59573 chebi_ph7_3 GO:0071915 biolink:BiologicalProcess protein-lysine lysylation The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P). go-plus.json protein amino acid lysylation http://purl.obolibrary.org/obo/GO_0071915 CHEBI:60598 biolink:ChemicalSubstance opioid agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_60598 CHEBI:84550 biolink:ChemicalSubstance menaquinol-12 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84550 chebi_ph7_3 GO:0071914 biolink:CellularComponent prominosome An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known. go-plus.json prominin-containing extracellular membrane vesicle http://purl.obolibrary.org/obo/GO_0071914 GO:0046979 biolink:MolecularActivity TAP2 binding Binding to the TAP2 subunit of TAP (transporter associated with antigen processing) protein. go-plus.json http://purl.obolibrary.org/obo/GO_0046979 GO:0071913 biolink:MolecularActivity citrate secondary active transmembrane transporter activity Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. go-plus.json citrate carrier activity http://purl.obolibrary.org/obo/GO_0071913 GO:0046978 biolink:MolecularActivity TAP1 binding Binding to the TAP1 subunit of TAP (transporter associated with antigen processing) protein. go-plus.json http://purl.obolibrary.org/obo/GO_0046978 GO:0071912 biolink:BiologicalProcess asynchronous neurotransmitter secretion Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion. go-plus.json http://purl.obolibrary.org/obo/GO_0071912 GO:0071911 biolink:BiologicalProcess synchronous neurotransmitter secretion Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion. go-plus.json http://purl.obolibrary.org/obo/GO_0071911 GO:0046977 biolink:MolecularActivity TAP binding Binding to TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2. go-plus.json http://purl.obolibrary.org/obo/GO_0046977 GO:0071910 biolink:BiologicalProcess determination of liver left/right asymmetry Determination of the asymmetric location of the liver with respect to the left and right halves of the organism. go-plus.json http://purl.obolibrary.org/obo/GO_0071910 GO:0032302 biolink:CellularComponent MutSbeta complex A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3. go-plus.json MSH2/MSH3 complex|MMR complex http://purl.obolibrary.org/obo/GO_0032302 GO:0032301 biolink:CellularComponent MutSalpha complex A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6. go-plus.json MSH2/MSH6 complex|MMR complex http://purl.obolibrary.org/obo/GO_0032301 GO:0032300 biolink:CellularComponent mismatch repair complex Any complex formed of proteins that act in mismatch repair. go-plus.json http://purl.obolibrary.org/obo/GO_0032300 goslim_pir GO:1900808 biolink:BiologicalProcess fumigaclavine C catabolic process The chemical reactions and pathways resulting in the breakdown of fumigaclavine C. go-plus.json fumigaclavine C catabolism|fumigaclavine C degradation|fumigaclavine C breakdown http://purl.obolibrary.org/obo/GO_1900808 GO:1900807 biolink:BiologicalProcess fumigaclavine C metabolic process The chemical reactions and pathways involving fumigaclavine C. go-plus.json fumigaclavine C metabolism http://purl.obolibrary.org/obo/GO_1900807 GO:1900809 biolink:BiologicalProcess fumigaclavine C biosynthetic process The chemical reactions and pathways resulting in the formation of fumigaclavine C. go-plus.json fumigaclavine C formation|fumigaclavine C biosynthesis|fumigaclavine C anabolism|fumigaclavine C synthesis http://purl.obolibrary.org/obo/GO_1900809 GO:1900815 biolink:BiologicalProcess monodictyphenone biosynthetic process The chemical reactions and pathways resulting in the formation of monodictyphenone. go-plus.json monodictyphenone anabolism|monodictyphenone synthesis|monodictyphenone formation|monodictyphenone biosynthesis http://purl.obolibrary.org/obo/GO_1900815 GO:1900814 biolink:BiologicalProcess monodictyphenone catabolic process The chemical reactions and pathways resulting in the breakdown of monodictyphenone. go-plus.json monodictyphenone degradation|monodictyphenone catabolism|monodictyphenone breakdown http://purl.obolibrary.org/obo/GO_1900814 GO:1900817 biolink:BiologicalProcess ochratoxin A catabolic process The chemical reactions and pathways resulting in the breakdown of ochratoxin A. go-plus.json Ochratoxin A catabolic process|ochratoxin A catabolism|Ochratoxin A catabolism|Ochratoxin A degradation|ochratoxin A degradation|Ochratoxin A breakdown|ochratoxin A breakdown http://purl.obolibrary.org/obo/GO_1900817 GO:1900816 biolink:BiologicalProcess ochratoxin A metabolic process The chemical reactions and pathways involving ochratoxin A. go-plus.json Ochratoxin A metabolism|Ochratoxin A metabolic process http://purl.obolibrary.org/obo/GO_1900816 GO:1900811 biolink:BiologicalProcess helvolic acid catabolic process The chemical reactions and pathways resulting in the breakdown of helvolic acid. go-plus.json Fumigacin catabolic process|helvolic acid catabolism|Fumigacin catabolism|helvolic acid degradation|Fumigacin degradation|helvolic acid breakdown|Fumigacin breakdown http://purl.obolibrary.org/obo/GO_1900811 GO:0007339 biolink:BiologicalProcess binding of sperm to zona pellucida The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place. go-plus.json ZPG binding http://purl.obolibrary.org/obo/GO_0007339 GO:0007338 biolink:BiologicalProcess single fertilization The union of male and female gametes to form a zygote. go-plus.json zygote biosynthesis|zygote formation http://purl.obolibrary.org/obo/GO_0007338 GO:1900810 biolink:BiologicalProcess helvolic acid metabolic process The chemical reactions and pathways involving helvolic acid. go-plus.json helvolic acid metabolism|Fumigacin metabolism|Fumigacin metabolic process http://purl.obolibrary.org/obo/GO_1900810 GO:1900813 biolink:BiologicalProcess monodictyphenone metabolic process The chemical reactions and pathways involving monodictyphenone. go-plus.json monodictyphenone metabolism http://purl.obolibrary.org/obo/GO_1900813 GO:0007337 biolink:BiologicalProcess obsolete unilateral process OBSOLETE. (Was not defined before being made obsolete). go-plus.json unilateral process http://purl.obolibrary.org/obo/GO_0007337 GO:1900812 biolink:BiologicalProcess helvolic acid biosynthetic process The chemical reactions and pathways resulting in the formation of helvolic acid. go-plus.json helvolic acid anabolism|Fumigacin anabolism|helvolic acid synthesis|Fumigacin synthesis|helvolic acid formation|Fumigacin formation|helvolic acid biosynthesis|Fumigacin biosynthetic process|Fumigacin biosynthesis http://purl.obolibrary.org/obo/GO_1900812 GO:0007336 biolink:BiologicalProcess obsolete bilateral process OBSOLETE. (Was not defined before being made obsolete). go-plus.json bilateral process http://purl.obolibrary.org/obo/GO_0007336 GO:0046987 biolink:MolecularActivity N-acetyllactosamine beta-1,3-glucuronosyltransferase activity Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine). go-plus.json galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity http://purl.obolibrary.org/obo/GO_0046987 GO:0007335 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007335 GO:0046986 biolink:BiologicalProcess negative regulation of hemoglobin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. go-plus.json negative regulation of haemoglobin biosynthetic process|negative regulation of haemoglobin biosynthesis|down regulation of hemoglobin biosynthetic process|downregulation of hemoglobin biosynthetic process|negative regulation of hemoglobin biosynthesis|negative regulation of hemoglobin anabolism|down-regulation of hemoglobin biosynthetic process|negative regulation of hemoglobin synthesis|negative regulation of hemoglobin formation|inhibition of hemoglobin biosynthetic process http://purl.obolibrary.org/obo/GO_0046986 GO:0007334 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007334 GO:0046985 biolink:BiologicalProcess positive regulation of hemoglobin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. go-plus.json positive regulation of haemoglobin biosynthesis|positive regulation of haemoglobin biosynthetic process|up regulation of hemoglobin biosynthetic process|activation of hemoglobin biosynthetic process|positive regulation of hemoglobin biosynthesis|stimulation of hemoglobin biosynthetic process|positive regulation of hemoglobin anabolism|up-regulation of hemoglobin biosynthetic process|positive regulation of hemoglobin synthesis|positive regulation of hemoglobin formation|upregulation of hemoglobin biosynthetic process http://purl.obolibrary.org/obo/GO_0046985 GO:0007333 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007333 GO:0046984 biolink:BiologicalProcess regulation of hemoglobin biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. go-plus.json regulation of hemoglobin biosynthesis|regulation of haemoglobin biosynthesis|regulation of haemoglobin biosynthetic process|regulation of hemoglobin anabolism|regulation of hemoglobin synthesis|regulation of hemoglobin formation http://purl.obolibrary.org/obo/GO_0046984 GO:0007332 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007332 GO:0007331 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007331 GO:0046983 biolink:MolecularActivity protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. go-plus.json http://purl.obolibrary.org/obo/GO_0046983 GO:0046982 biolink:MolecularActivity protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer. go-plus.json http://purl.obolibrary.org/obo/GO_0046982 goslim_chembl GO:0007330 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007330 GO:0046981 biolink:MolecularActivity beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids. go-plus.json UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity http://purl.obolibrary.org/obo/GO_0046981 GO:0046980 biolink:MolecularActivity tapasin binding Binding to tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules. go-plus.json TAPBP binding|TAP binding protein binding http://purl.obolibrary.org/obo/GO_0046980 CHEBI:59564 biolink:ChemicalSubstance thermospermine go-plus.json http://purl.obolibrary.org/obo/CHEBI_59564 CHEBI:142839 biolink:ChemicalSubstance enolate go-plus.json http://purl.obolibrary.org/obo/CHEBI_142839 CHEBI:35596 biolink:ChemicalSubstance (+)-pulegone go-plus.json http://purl.obolibrary.org/obo/CHEBI_35596 chebi_ph7_3 GO:0071949 biolink:MolecularActivity FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json oxidized flavin adenine dinucleotide binding|oxidized flavine-adenine dinucleotide binding http://purl.obolibrary.org/obo/GO_0071949 CHEBI:59562 biolink:ChemicalSubstance 5-hydroxyisouric acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59562 chebi_ph7_3 GO:0071948 biolink:BiologicalProcess activation-induced B cell apoptotic process B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death. go-plus.json activated B cell apoptosis|activation-induced cell death of B lymphocytes|activation-induced B cell apoptosis|activation-induced B-cell apoptosis|antigen-driven apoptosis|activation-induced cell death of B cells|activation-induced cell death of B-lymphocytes|AICD|activation-induced cell death of B-cells http://purl.obolibrary.org/obo/GO_0071948 CHEBI:84561 biolink:ChemicalSubstance 2,4-dinitrophenol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84561 chebi_ph7_3 CHEBI:59561 biolink:ChemicalSubstance diamino acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59561 CHEBI:59560 biolink:ChemicalSubstance sapropterin go-plus.json http://purl.obolibrary.org/obo/CHEBI_59560 chebi_ph7_3 GO:0071947 biolink:BiologicalProcess protein deubiquitination involved in ubiquitin-dependent protein catabolic process The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism. go-plus.json http://purl.obolibrary.org/obo/GO_0071947 GO:0071946 biolink:BiologicalProcess cis-acting DNA replication termination A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing. go-plus.json cis acting DNA replication termination http://purl.obolibrary.org/obo/GO_0071946 GO:0071945 biolink:BiologicalProcess regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein. go-plus.json regulation of flagellar cell motility by regulation of motor speed|regulation of bacterial-type flagellar cell motility by regulation of motor speed|regulation of bacterial-type flagellum cell motility by regulation of motor speed http://purl.obolibrary.org/obo/GO_0071945 GO:0046989 biolink:MolecularActivity galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids. go-plus.json http://purl.obolibrary.org/obo/GO_0046989 GO:0071944 biolink:CellularComponent cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. go-plus.json http://purl.obolibrary.org/obo/GO_0071944 goslim_flybase_ribbon GO:0046988 biolink:MolecularActivity asioloorosomucoid beta-1,3-glucuronosyltransferase activity Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid. go-plus.json http://purl.obolibrary.org/obo/GO_0046988 GO:0071943 biolink:CellularComponent Myc-Max complex A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max. go-plus.json http://purl.obolibrary.org/obo/GO_0071943 GO:0071942 biolink:CellularComponent XPC complex A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2. go-plus.json http://purl.obolibrary.org/obo/GO_0071942 GO:0071941 biolink:BiologicalProcess nitrogen cycle metabolic process A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization. Wikipedia:Nitrogen_cycle go-plus.json http://purl.obolibrary.org/obo/GO_0071941 goslim_generic|goslim_pombe|goslim_chembl GO:0071940 biolink:BiologicalProcess fungal-type cell wall assembly The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall. go-plus.json fungal-type cell wall formation http://purl.obolibrary.org/obo/GO_0071940 GO:1900819 biolink:BiologicalProcess orlandin metabolic process The chemical reactions and pathways involving orlandin. go-plus.json orlandin metabolism http://purl.obolibrary.org/obo/GO_1900819 CHEBI:35593 biolink:ChemicalSubstance 4H-pyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_35593 chebi_ph7_3 GO:1900818 biolink:BiologicalProcess ochratoxin A biosynthetic process The chemical reactions and pathways resulting in the formation of ochratoxin A. go-plus.json Ochratoxin A anabolism|Ochratoxin A synthesis|Ochratoxin A formation|Ochratoxin A biosynthesis|Ochratoxin A biosynthetic process http://purl.obolibrary.org/obo/GO_1900818 CHEBI:35592 biolink:ChemicalSubstance 2H-pyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_35592 chebi_ph7_3 CHEBI:35594 biolink:ChemicalSubstance pyran go-plus.json http://purl.obolibrary.org/obo/CHEBI_35594 GO:0046990 biolink:MolecularActivity N-hydroxyarylamine O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine. EC:2.3.1.118|MetaCyc:2.3.1.118-RXN|RHEA:20277 go-plus.json N-hydroxy-2-aminofluorene-O-acetyltransferase activity|acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity|arylhydroxamate N,O-acetyltransferase activity http://purl.obolibrary.org/obo/GO_0046990 GO:1900826 biolink:BiologicalProcess negative regulation of membrane depolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. go-plus.json down regulation of membrane depolarization during cardiac muscle cell action potential|downregulation of membrane depolarization during cardiac muscle cell action potential|down-regulation of membrane depolarization during of cardiac muscle cell action potential|inhibition of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1900826 GO:1900825 biolink:BiologicalProcess regulation of membrane depolarization during cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. go-plus.json http://purl.obolibrary.org/obo/GO_1900825 GO:1900828 biolink:BiologicalProcess D-tyrosine metabolic process The chemical reactions and pathways involving D-tyrosine. go-plus.json D-tyrosine metabolism http://purl.obolibrary.org/obo/GO_1900828 GO:1900827 biolink:BiologicalProcess positive regulation of membrane depolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. go-plus.json up regulation of membrane depolarization during cardiac muscle cell action potential|activation of membrane depolarization during cardiac muscle cell action potential|up-regulation of membrane depolarization during cardiac muscle cell action potential|upregulation of membrane depolarization during cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_1900827 GO:1900822 biolink:BiologicalProcess regulation of ergot alkaloid biosynthetic process Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process. go-plus.json regulation of ergot alkaloid synthesis|regulation of ergot alkaloid formation|regulation of ergot alkaloid biosynthesis|regulation of ergot alkaloid anabolism http://purl.obolibrary.org/obo/GO_1900822 GO:0007349 biolink:BiologicalProcess cellularization The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development. go-plus.json http://purl.obolibrary.org/obo/GO_0007349 GO:1900821 biolink:BiologicalProcess orlandin biosynthetic process The chemical reactions and pathways resulting in the formation of orlandin. go-plus.json orlandin synthesis|orlandin formation|orlandin biosynthesis|orlandin anabolism http://purl.obolibrary.org/obo/GO_1900821 GO:1900824 biolink:BiologicalProcess positive regulation of ergot alkaloid biosynthetic process Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process. go-plus.json positive regulation of ergot alkaloid formation|up regulation of ergot alkaloid formation|up-regulation of ergot alkaloid biosynthetic process|up-regulation of ergot alkaloid biosynthesis|upregulation of ergot alkaloid anabolism|upregulation of ergot alkaloid synthesis|upregulation of ergot alkaloid formation|upregulation of ergot alkaloid biosynthesis|upregulation of ergot alkaloid biosynthetic process|up-regulation of ergot alkaloid anabolism|up-regulation of ergot alkaloid synthesis|activation of ergot alkaloid anabolism|up-regulation of ergot alkaloid formation|up regulation of ergot alkaloid biosynthetic process|up regulation of ergot alkaloid biosynthesis|activation of ergot alkaloid synthesis|activation of ergot alkaloid biosynthetic process|positive regulation of ergot alkaloid anabolism|positive regulation of ergot alkaloid biosynthesis|activation of ergot alkaloid formation|up regulation of ergot alkaloid anabolism|positive regulation of ergot alkaloid synthesis|activation of ergot alkaloid biosynthesis|up regulation of ergot alkaloid synthesis http://purl.obolibrary.org/obo/GO_1900824 GO:0007348 biolink:BiologicalProcess regulation of syncytial blastoderm mitotic cell cycle A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle. go-plus.json syncytial blastoderm cell cycle modulation|modulation of syncytial blastoderm cell cycle progression|regulation of syncytial blastoderm cell cycle|regulation of syncytial blastoderm cell cycle progression|syncytial blastoderm cell cycle regulation|regulation of progression through syncytial blastoderm mitotic cell cycle|syncytial blastoderm cell cycle regulator http://purl.obolibrary.org/obo/GO_0007348 GO:0007347 biolink:BiologicalProcess regulation of preblastoderm mitotic cell cycle A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle. go-plus.json regulation of preblastoderm mitotic cell cycle progression|preblastoderm mitotic cell cycle modulation|modulation of preblastoderm mitotic cell cycle progression|regulation of progression through preblastoderm mitotic cell cycle|preblastoderm mitotic cell cycle regulator|preblastoderm mitotic cell cycle regulation http://purl.obolibrary.org/obo/GO_0007347 GO:1900823 biolink:BiologicalProcess negative regulation of ergot alkaloid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process. go-plus.json downregulation of ergot alkaloid synthesis|down regulation of ergot alkaloid anabolism|inhibition of ergot alkaloid biosynthetic process|downregulation of ergot alkaloid formation|down regulation of ergot alkaloid synthesis|inhibition of ergot alkaloid anabolism|inhibition of ergot alkaloid biosynthesis|down regulation of ergot alkaloid formation|inhibition of ergot alkaloid synthesis|inhibition of ergot alkaloid formation|down regulation of ergot alkaloid biosynthetic process|down regulation of ergot alkaloid biosynthesis|downregulation of ergot alkaloid biosynthetic process|downregulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid anabolism|negative regulation of ergot alkaloid anabolism|down-regulation of ergot alkaloid synthesis|negative regulation of ergot alkaloid synthesis|down-regulation of ergot alkaloid formation|negative regulation of ergot alkaloid formation|down-regulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid biosynthetic process|negative regulation of ergot alkaloid biosynthesis|downregulation of ergot alkaloid anabolism http://purl.obolibrary.org/obo/GO_1900823 GO:0007346 biolink:BiologicalProcess regulation of mitotic cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle. go-plus.json mitotic cell cycle modulation|regulation of mitotic cell cycle progression|mitotic cell cycle regulation|modulation of mitotic cell cycle progression|regulation of progression through mitotic cell cycle|mitotic cell cycle regulator http://purl.obolibrary.org/obo/GO_0007346 GO:0046998 biolink:MolecularActivity (S)-usnate reductase activity Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH. KEGG_REACTION:R07345|MetaCyc:1.1.1.199-RXN|EC:1.1.1.199|RHEA:21876 go-plus.json L-usnic acid dehydrogenase activity|reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming) http://purl.obolibrary.org/obo/GO_0046998 GO:0007345 biolink:BiologicalProcess obsolete embryogenesis and morphogenesis OBSOLETE. Formation and development of an embryo and its organized structures. go-plus.json embryogenesis and morphogenesis http://purl.obolibrary.org/obo/GO_0007345 GO:0046997 biolink:MolecularActivity oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin. EC:1.5.8.- go-plus.json http://purl.obolibrary.org/obo/GO_0046997 GO:0007344 biolink:BiologicalProcess pronuclear fusion The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome. go-plus.json http://purl.obolibrary.org/obo/GO_0007344 GO:0046996 biolink:MolecularActivity obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated. EC:1.14.21.- go-plus.json oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated http://purl.obolibrary.org/obo/GO_0046996 GO:1900820 biolink:BiologicalProcess orlandin catabolic process The chemical reactions and pathways resulting in the breakdown of orlandin. go-plus.json orlandin catabolism|orlandin degradation|orlandin breakdown http://purl.obolibrary.org/obo/GO_1900820 GO:0046995 biolink:MolecularActivity oxidoreductase activity, acting on hydrogen as donor, with other known acceptors Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound. EC:1.12.98.- go-plus.json http://purl.obolibrary.org/obo/GO_0046995 GO:0007343 biolink:BiologicalProcess egg activation The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. Wikipedia:Egg_activation go-plus.json http://purl.obolibrary.org/obo/GO_0007343 GO:0046994 biolink:MolecularActivity oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound. EC:1.12.5.- go-plus.json http://purl.obolibrary.org/obo/GO_0046994 CHEBI:84579 biolink:ChemicalSubstance 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydroinden-4-yl]propanoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84579 GO:0007342 biolink:BiologicalProcess fusion of sperm to egg plasma membrane involved in single fertilization The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head. go-plus.json sperm-oocyte fusion http://purl.obolibrary.org/obo/GO_0007342 GO:0046993 biolink:MolecularActivity oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen. EC:1.21.3.- go-plus.json http://purl.obolibrary.org/obo/GO_0046993 GO:0007341 biolink:BiologicalProcess penetration of zona pellucida The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm. go-plus.json http://purl.obolibrary.org/obo/GO_0007341 GO:0046992 biolink:MolecularActivity oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y. EC:1.21.-.- go-plus.json oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors http://purl.obolibrary.org/obo/GO_0046992 GO:0007340 biolink:BiologicalProcess acrosome reaction The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida. Wikipedia:Acrosome_reaction go-plus.json http://purl.obolibrary.org/obo/GO_0007340 CHEBI:84576 biolink:ChemicalSubstance (25S)-3beta-hydroxy-5-cholesten-26-oyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84576 GO:0046991 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046991 GO:0071939 biolink:BiologicalProcess vitamin A import The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid. go-plus.json vitamin A uptake http://purl.obolibrary.org/obo/GO_0071939 GO:0071938 biolink:BiologicalProcess vitamin A transport The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid. go-plus.json vitamin A uptake and transport http://purl.obolibrary.org/obo/GO_0071938 CHEBI:84572 biolink:ChemicalSubstance 27-O-demethylrifamycin SV(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84572 chebi_ph7_3 GO:0071937 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071937 CHEBI:84571 biolink:ChemicalSubstance rifamycin SV(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84571 chebi_ph7_3 GO:0071936 biolink:MolecularActivity coreceptor activity involved in Wnt signaling pathway In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway. go-plus.json coreceptor activity involved in Wnt receptor signalling pathway|Wnt co-receptor activity|coreceptor activity involved in Wnt-activated signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway http://purl.obolibrary.org/obo/GO_0071936 CHEBI:142823 biolink:ChemicalSubstance andrastin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142823 chebi_ph7_3 CHEBI:166856 biolink:ChemicalSubstance hydroxytrimethylaminium go-plus.json http://purl.obolibrary.org/obo/CHEBI_166856 GO:0071935 biolink:BiologicalProcess octopamine signaling pathway involved in response to food The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus. go-plus.json octopamine signalling pathway involved in response to food http://purl.obolibrary.org/obo/GO_0071935 CHEBI:142822 biolink:ChemicalSubstance andrastin B(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142822 chebi_ph7_3 GO:0071934 biolink:BiologicalProcess thiamine transmembrane transport The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. go-plus.json thiamin transmembrane transport|vitamin B1 transmembrane transport|thiamine membrane transport http://purl.obolibrary.org/obo/GO_0071934 CHEBI:142821 biolink:ChemicalSubstance andrastin C(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142821 chebi_ph7_3 GO:0046999 biolink:BiologicalProcess regulation of conjugation Any process that modulates the rate or frequency of conjugation, the union or introduction of genetic information from compatible mating types that results in a genetically different individual. go-plus.json http://purl.obolibrary.org/obo/GO_0046999 GO:0071933 biolink:MolecularActivity Arp2/3 complex binding Binding to an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5). go-plus.json http://purl.obolibrary.org/obo/GO_0071933 GO:0071932 biolink:BiologicalProcess replication fork reversal Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved. go-plus.json http://purl.obolibrary.org/obo/GO_0071932 GO:0071931 biolink:BiologicalProcess positive regulation of transcription involved in G1/S transition of mitotic cell cycle Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle. go-plus.json positive regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0071931 GO:0071930 biolink:BiologicalProcess negative regulation of transcription involved in G1/S transition of mitotic cell cycle Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle. go-plus.json negative regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0071930 CHEBI:59558 biolink:ChemicalSubstance medium-chain fatty acid anion go-plus.json http://purl.obolibrary.org/obo/CHEBI_59558 chebi_ph7_3 GO:1900829 biolink:BiologicalProcess D-tyrosine catabolic process The chemical reactions and pathways resulting in the breakdown of D-tyrosine. go-plus.json D-tyrosine degradation|D-tyrosine breakdown|D-tyrosine catabolism http://purl.obolibrary.org/obo/GO_1900829 CHEBI:59554 biolink:ChemicalSubstance medium-chain fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59554 GO:1900837 biolink:BiologicalProcess regulation of fumigaclavine C biosynthetic process Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process. go-plus.json regulation of fumigaclavine C anabolism|regulation of fumigaclavine C synthesis|regulation of fumigaclavine C biosynthesis|regulation of fumigaclavine C formation http://purl.obolibrary.org/obo/GO_1900837 GO:1900836 biolink:BiologicalProcess positive regulation of emericellin biosynthetic process Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_1900836 GO:0007319 biolink:BiologicalProcess negative regulation of oskar mRNA translation Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein. go-plus.json down regulation of oskar mRNA translation|inhibition of oskar mRNA translation|down-regulation of oskar mRNA translation|downregulation of oskar mRNA translation http://purl.obolibrary.org/obo/GO_0007319 GO:1900839 biolink:BiologicalProcess positive regulation of fumigaclavine C biosynthetic process Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process. go-plus.json upregulation of fumigaclavine C biosynthetic process|up-regulation of fumigaclavine C biosynthetic process|up regulation of fumigaclavine C biosynthetic process http://purl.obolibrary.org/obo/GO_1900839 GO:1900838 biolink:BiologicalProcess negative regulation of fumigaclavine C biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process. go-plus.json inhibition of fumigaclavine C biosynthetic process http://purl.obolibrary.org/obo/GO_1900838 GO:0007318 biolink:BiologicalProcess pole plasm protein localization Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. go-plus.json establishment and maintenance of pole plasm protein localization|oocyte pole plasm protein localization|pole plasm protein localisation http://purl.obolibrary.org/obo/GO_0007318 GO:0007317 biolink:BiologicalProcess regulation of pole plasm oskar mRNA localization Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. go-plus.json regulation of oocyte pole plasm oskar mRNA localization|regulation of pole plasm oskar mRNA localisation http://purl.obolibrary.org/obo/GO_0007317 GO:1900833 biolink:BiologicalProcess D-leucine biosynthetic process The chemical reactions and pathways resulting in the formation of D-leucine. go-plus.json D-leucine anabolism|D-leucine synthesis|D-leucine formation|D-leucine biosynthesis http://purl.obolibrary.org/obo/GO_1900833 GO:1900832 biolink:BiologicalProcess D-leucine catabolic process The chemical reactions and pathways resulting in the breakdown of D-leucine. go-plus.json D-leucine degradation|D-leucine breakdown|D-leucine catabolism http://purl.obolibrary.org/obo/GO_1900832 GO:0007316 biolink:BiologicalProcess pole plasm RNA localization Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. go-plus.json pole plasm RNA localisation|establishment and maintenance of pole plasm RNA localization|oocyte pole plasm RNA localization http://purl.obolibrary.org/obo/GO_0007316 GO:1900835 biolink:BiologicalProcess negative regulation of emericellin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process. go-plus.json down-regulation of emericellin biosynthetic process|downregulation of emericellin biosynthetic process|down regulation of emericellin biosynthetic process http://purl.obolibrary.org/obo/GO_1900835 GO:0007315 biolink:BiologicalProcess pole plasm assembly Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster. go-plus.json http://purl.obolibrary.org/obo/GO_0007315 GO:1900834 biolink:BiologicalProcess regulation of emericellin biosynthetic process Any process that modulates the frequency, rate or extent of emericellin biosynthetic process. go-plus.json regulation of emericellin formation|regulation of Variecoxanthone B formation|regulation of emericellin biosynthesis|regulation of emericellin anabolism|regulation of Variecoxanthone B anabolism|regulation of Variecoxanthone B biosynthesis|regulation of Variecoxanthone B biosynthetic process|regulation of emericellin synthesis|regulation of Variecoxanthone B synthesis http://purl.obolibrary.org/obo/GO_1900834 GO:0007314 biolink:BiologicalProcess oocyte anterior/posterior axis specification Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster. go-plus.json oocyte anterior/posterior axis determination http://purl.obolibrary.org/obo/GO_0007314 GO:0007313 biolink:BiologicalProcess maternal specification of dorsal/ventral axis, oocyte, soma encoded Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster. go-plus.json maternal determination of dorsal/ventral axis, oocyte, soma encoded|maternal specification of dorsoventral axis, oocyte, soma encoded|maternal specification of dorsal-ventral axis, oocyte, soma encoded http://purl.obolibrary.org/obo/GO_0007313 GO:0007312 biolink:BiologicalProcess oocyte nucleus migration involved in oocyte dorsal/ventral axis specification The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster. go-plus.json establishment of oocyte nucleus localization during oocyte axis determination|oocyte nucleus migration during oocyte axis specification|oocyte axis determination, oocyte nucleus migration|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification|establishment of localization of oocyte nucleus during oocyte axis determination|oocyte axis determination, positioning of nucleus|oocyte axis determination, establishment of localization of nucleus|establishment of oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|establishment of oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte axis determination, oocyte nuclear migration|oocyte axis determination, establishment of position of nucleus|oocyte axis determination, establishment of oocyte nucleus localization|nucleus positioning in oocyte during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|oocyte nuclear migration during oocyte axis determination|oocyte nucleus migration during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsoventral axis specification|oocyte nucleus positioning during oocyte axis determination http://purl.obolibrary.org/obo/GO_0007312 GO:0007311 biolink:BiologicalProcess maternal specification of dorsal/ventral axis, oocyte, germ-line encoded Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster. go-plus.json maternal determination of dorsal/ventral axis, oocyte, germ-line encoded|maternal specification of dorsal-ventral axis, oocyte, germ-line encoded|maternal specification of dorsoventral axis, oocyte, germ-line encoded http://purl.obolibrary.org/obo/GO_0007311 GO:1900831 biolink:BiologicalProcess D-leucine metabolic process The chemical reactions and pathways involving D-leucine. go-plus.json D-leucine metabolism http://purl.obolibrary.org/obo/GO_1900831 GO:1900830 biolink:BiologicalProcess obsolete D-tyrosine biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of D-tyrosine. go-plus.json D-tyrosine biosynthesis|D-tyrosine anabolism|D-tyrosine synthesis|D-tyrosine formation http://purl.obolibrary.org/obo/GO_1900830 GO:0007310 biolink:BiologicalProcess oocyte dorsal/ventral axis specification The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster. go-plus.json oocyte dorsal-ventral axis specification|oocyte dorsoventral axis specification|oocyte dorsal/ventral axis determination http://purl.obolibrary.org/obo/GO_0007310 CHEBI:84589 biolink:ChemicalSubstance mitomycin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84589 chebi_ph7_3 UBERON:2000440 biolink:AnatomicalEntity superior raphe nucleus go-plus.json anterior raphe nucleus http://purl.obolibrary.org/obo/UBERON_2000440 CHEBI:84588 biolink:ChemicalSubstance trans-2,3-unsaturated fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_84588 chebi_ph7_3 CHEBI:84587 biolink:ChemicalSubstance 2,3-saturated fatty aldehyde go-plus.json http://purl.obolibrary.org/obo/CHEBI_84587 chebi_ph7_3 CHEBI:59541 biolink:ChemicalSubstance coenzyme gamma-F420-2(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59541 CHEBI:84584 biolink:ChemicalSubstance 3-oxodotriacontanoyl-CoA go-plus.json http://purl.obolibrary.org/obo/CHEBI_84584 GO:0071969 biolink:BiologicalProcess fungal-type cell wall (1->3)-beta-D-glucan metabolic process The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi. go-plus.json fungal-type cell wall beta-1,3 glucan metabolism|fungal-type cell wall 1,3-beta-glucan metabolism|fungal-type cell wall beta-1,3 glucan metabolic process|fungal-type cell wall 1,3-beta-D-glucan metabolic process http://purl.obolibrary.org/obo/GO_0071969 CHEBI:35579 biolink:ChemicalSubstance 3H-indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35579 chebi_ph7_3 GO:0071968 biolink:MolecularActivity lipid A-core heptosyltransferase activity Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+. MetaCyc:RXN0-5127|RHEA:30019 go-plus.json http://purl.obolibrary.org/obo/GO_0071968 CHEBI:84581 biolink:ChemicalSubstance 1,2,2'-trilinoleoyl-,1'-monolysocardiolipin go-plus.json http://purl.obolibrary.org/obo/CHEBI_84581 GO:0071967 biolink:MolecularActivity lipopolysaccharide core heptosyltransferase activity Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+. MetaCyc:RXN0-5122|RHEA:29923 go-plus.json LPS core heptosyltransferase activity http://purl.obolibrary.org/obo/GO_0071967 CHEBI:84580 biolink:ChemicalSubstance dinitroanisoles go-plus.json http://purl.obolibrary.org/obo/CHEBI_84580 GO:0071966 biolink:BiologicalProcess fungal-type cell wall polysaccharide metabolic process The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall. go-plus.json http://purl.obolibrary.org/obo/GO_0071966 GO:0071965 biolink:BiologicalProcess multicellular organismal locomotion Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another. go-plus.json http://purl.obolibrary.org/obo/GO_0071965 GO:0071964 biolink:BiologicalProcess establishment of cell polarity regulating cell shape Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0071964 CHEBI:59549 biolink:ChemicalSubstance essential fatty acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_59549 GO:0071963 biolink:BiologicalProcess establishment or maintenance of cell polarity regulating cell shape Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0071963 GO:0071962 biolink:BiologicalProcess mitotic sister chromatid cohesion, centromeric The cell cycle process in which centromeres of sister chromatids are joined during mitosis. go-plus.json centromeric mitotic sister chromatin cohesion|sister chromatid cohesion at centromere at mitosis|mitotic sister chromatid cohesion at centromere http://purl.obolibrary.org/obo/GO_0071962 GO:0071961 biolink:BiologicalProcess mitotic sister chromatid cohesion, arms The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis. go-plus.json mitotic sister chromatid cohesion along arms|sister chromatid cohesion along arms at mitosis http://purl.obolibrary.org/obo/GO_0071961 CHEBI:35571 biolink:ChemicalSubstance mancude organic heterocyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35571 CHEBI:59546 biolink:ChemicalSubstance 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_59546 CHEBI:59545 biolink:ChemicalSubstance 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59545 chebi_ph7_3 GO:0071960 biolink:BiologicalProcess maintenance of mitotic sister chromatid cohesion, centromeric The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. go-plus.json maintenance of sister chromatin cohesion at centromere at mitosis|maintenance of centromeric mitotic sister chromatin cohesion|maintenance of mitotic sister chromatin cohesion at centromere http://purl.obolibrary.org/obo/GO_0071960 CHEBI:35570 biolink:ChemicalSubstance mancude organic heterobicyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35570 CHEBI:59544 biolink:ChemicalSubstance phosphoantigen go-plus.json http://purl.obolibrary.org/obo/CHEBI_59544 CHEBI:35573 biolink:ChemicalSubstance organic mancude parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35573 CHEBI:59543 biolink:ChemicalSubstance coenzyme F420-1(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59543 GO:1900848 biolink:BiologicalProcess positive regulation of naphtho-gamma-pyrone biosynthetic process Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process. go-plus.json up-regulation of naphtho-gamma-pyrone biosynthetic process|upregulation of naphtho-gamma-pyrone biosynthetic process|up regulation of naphtho-gamma-pyrone biosynthetic process|activation of naphtho-gamma-pyrone biosynthetic process http://purl.obolibrary.org/obo/GO_1900848 GO:1900847 biolink:BiologicalProcess negative regulation of naphtho-gamma-pyrone biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process. go-plus.json inhibition of naphtho-gamma-pyrone biosynthetic process|down regulation of naphtho-gamma-pyrone biosynthetic process|downregulation of naphtho-gamma-pyrone biosynthetic process|down-regulation of naphtho-gamma-pyrone biosynthetic process http://purl.obolibrary.org/obo/GO_1900847 GO:0007329 biolink:BiologicalProcess positive regulation of transcription from RNA polymerase II promoter by pheromones Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter. go-plus.json up-regulation of transcription from RNA polymerase II promoter by pheromones|positive regulation of transcription from Pol II promoter by pheromones|upregulation of transcription from RNA polymerase II promoter by pheromones|up regulation of transcription from RNA polymerase II promoter by pheromones|activation of transcription from RNA polymerase II promoter by pheromones|stimulation of transcription from RNA polymerase II promoter by pheromones http://purl.obolibrary.org/obo/GO_0007329 GO:1900849 biolink:BiologicalProcess regulation of pseurotin A biosynthetic process Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process. go-plus.json regulation of Pseurotin anabolism|regulation of pseurotin A formation|regulation of Pseurotin synthesis|regulation of Pseurotin formation|regulation of pseurotin A biosynthesis|regulation of Pseurotin biosynthesis|regulation of Pseurotin biosynthetic process|regulation of pseurotin A anabolism|regulation of pseurotin A synthesis http://purl.obolibrary.org/obo/GO_1900849 GO:1900844 biolink:BiologicalProcess negative regulation of monodictyphenone biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process. go-plus.json down regulation of monodictyphenone biosynthetic process|downregulation of monodictyphenone biosynthetic process|down-regulation of monodictyphenone biosynthetic process http://purl.obolibrary.org/obo/GO_1900844 GO:0007328 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007328 GO:1900843 biolink:BiologicalProcess regulation of monodictyphenone biosynthetic process Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process. go-plus.json regulation of monodictyphenone biosynthesis|regulation of monodictyphenone anabolism|regulation of monodictyphenone synthesis|regulation of monodictyphenone formation http://purl.obolibrary.org/obo/GO_1900843 GO:0007327 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007327 GO:1900846 biolink:BiologicalProcess regulation of naphtho-gamma-pyrone biosynthetic process Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process. go-plus.json regulation of naphtho-gamma-pyrone synthesis|regulation of naphtho-gamma-pyrones biosynthesis|regulation of naphtho-gamma-pyrones biosynthetic process|regulation of naphtho-gamma-pyrone formation|regulation of naphtho-gamma-pyrone biosynthesis|regulation of naphtho-gamma-pyrones anabolism|regulation of naphtho-gamma-pyrones synthesis|regulation of naphtho-gamma-pyrones formation|regulation of naphtho-gamma-pyrone anabolism http://purl.obolibrary.org/obo/GO_1900846 GO:0007326 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007326 GO:1900845 biolink:BiologicalProcess positive regulation of monodictyphenone biosynthetic process Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process. go-plus.json upregulation of monodictyphenone biosynthetic process http://purl.obolibrary.org/obo/GO_1900845 GO:0007325 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007325 GO:1900840 biolink:BiologicalProcess regulation of helvolic acid biosynthetic process Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_1900840 GO:0007324 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007324 GO:0007323 biolink:BiologicalProcess peptide pheromone maturation The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae. go-plus.json pheromone processing http://purl.obolibrary.org/obo/GO_0007323 GO:1900842 biolink:BiologicalProcess positive regulation of helvolic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process. go-plus.json up regulation of helvolic acid biosynthetic process|upregulation of helvolic acid biosynthetic process|up-regulation of helvolic acid biosynthetic process http://purl.obolibrary.org/obo/GO_1900842 GO:0007322 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007322 GO:1900841 biolink:BiologicalProcess negative regulation of helvolic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process. go-plus.json downregulation of helvolic acid biosynthetic process|down regulation of helvolic acid biosynthetic process|down-regulation of helvolic acid biosynthetic process http://purl.obolibrary.org/obo/GO_1900841 GO:0007321 biolink:BiologicalProcess sperm displacement The physical displacement of sperm stored from previous mating encounters. go-plus.json http://purl.obolibrary.org/obo/GO_0007321 GO:0007320 biolink:BiologicalProcess insemination The introduction of semen or sperm into the genital tract of a female. Wikipedia:Insemination go-plus.json http://purl.obolibrary.org/obo/GO_0007320 CHEBI:84599 biolink:ChemicalSubstance all-trans-dodecaprenyl diphosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84599 CHEBI:35586 biolink:ChemicalSubstance 1H-purine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35586 CHEBI:59531 biolink:ChemicalSubstance F420-0(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59531 CHEBI:11596 biolink:ChemicalSubstance 2-hydroxyglutarate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_11596 chebi_ph7_3 UBERON:2000425 biolink:AnatomicalEntity anterior lateral line nerve Cranial nerve which enters the brain between cranial nerves VI and VII; contains afferents and sensory efferents to the anterior lateral line ganglia. go-plus.json rostral lateral line nerve http://purl.obolibrary.org/obo/UBERON_2000425 CHEBI:35588 biolink:ChemicalSubstance 3H-purine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35588 CHEBI:142803 biolink:ChemicalSubstance 2,3-cis-enoyl CoA(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_142803 chebi_ph7_3 GO:0071959 biolink:BiologicalProcess maintenance of mitotic sister chromatid cohesion, arms The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. go-plus.json maintenance of sister chromatin cohesion along arms at mitosis|maintenance of mitotic sister chromatin cohesion along arms http://purl.obolibrary.org/obo/GO_0071959 CHEBI:11594 biolink:ChemicalSubstance 2-coumarate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11594 chebi_ph7_3 GO:0071958 biolink:CellularComponent new mitotic spindle pole body The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize. go-plus.json new SPB http://purl.obolibrary.org/obo/GO_0071958 CHEBI:35589 biolink:ChemicalSubstance 9H-purine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35589 chebi_ph7_3 GO:0071957 biolink:CellularComponent old mitotic spindle pole body The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis. go-plus.json old SPB http://purl.obolibrary.org/obo/GO_0071957 CHEBI:84592 biolink:ChemicalSubstance 7-demethylmitomycin A(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84592 GO:0071956 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071956 CHEBI:84591 biolink:ChemicalSubstance 7-demethylmitomycin B(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84591 GO:0071955 biolink:BiologicalProcess recycling endosome to Golgi transport The directed movement of substances from recycling endosomes to the Golgi. go-plus.json http://purl.obolibrary.org/obo/GO_0071955 CHEBI:84590 biolink:ChemicalSubstance mitomycin B(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84590 chebi_ph7_3 GO:0071954 biolink:BiologicalProcess chemokine (C-C motif) ligand 11 production The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. go-plus.json C-C motif chemokine 11 production|CCL-11 production|eotaxin-1 production|CCL11 production|eotaxin production http://purl.obolibrary.org/obo/GO_0071954 gocheck_do_not_annotate CHEBI:59539 biolink:ChemicalSubstance coenzyme alpha-F420-3(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59539 GO:0071953 biolink:CellularComponent elastic fiber An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. go-plus.json elastic fibre|elastin fiber http://purl.obolibrary.org/obo/GO_0071953 GO:0071952 biolink:BiologicalProcess conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA. go-plus.json http://purl.obolibrary.org/obo/GO_0071952 CHEBI:35580 biolink:ChemicalSubstance N-oxide go-plus.json http://purl.obolibrary.org/obo/CHEBI_35580 CHEBI:59537 biolink:ChemicalSubstance coenzyme alpha-F420-3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_59537 GO:0071951 biolink:BiologicalProcess conversion of methionyl-tRNA to N-formyl-methionyl-tRNA The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet). go-plus.json http://purl.obolibrary.org/obo/GO_0071951 CHEBI:59536 biolink:ChemicalSubstance coenzyme F420-1 go-plus.json http://purl.obolibrary.org/obo/CHEBI_59536 GO:0071950 biolink:MolecularActivity FADH2 binding Binding to the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. go-plus.json reduced flavine-adenine dinucleotide binding|reduced flavin adenine dinucleotide binding http://purl.obolibrary.org/obo/GO_0071950 CHEBI:59535 biolink:ChemicalSubstance pyrimidoquinolines go-plus.json http://purl.obolibrary.org/obo/CHEBI_59535 CHEBI:35581 biolink:ChemicalSubstance indole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35581 CHEBI:35584 biolink:ChemicalSubstance purine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35584 CHEBI:59532 biolink:ChemicalSubstance F420-0 go-plus.json http://purl.obolibrary.org/obo/CHEBI_59532 GO:1900859 biolink:BiologicalProcess negative regulation of brevianamide F biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of brevianamide F biosynthetic process. go-plus.json down regulation of brevianamide F biosynthetic process|downregulation of brevianamide F biosynthetic process|down-regulation of brevianamide F biosynthetic process http://purl.obolibrary.org/obo/GO_1900859 GO:1900858 biolink:BiologicalProcess regulation of brevianamide F biosynthetic process Any process that modulates the frequency, rate or extent of brevianamide F biosynthetic process. go-plus.json regulation of brevianamide F synthesis|regulation of brevianamide F formation|regulation of brevianamide F biosynthesis|regulation of brevianamide F anabolism http://purl.obolibrary.org/obo/GO_1900858 GO:1900855 biolink:BiologicalProcess regulation of fumitremorgin B biosynthetic process Any process that modulates the frequency, rate or extent of fumitremorgin B biosynthetic process. go-plus.json regulation of Lanosulin synthesis|regulation of Lanosulin formation|regulation of fumitremorgin B biosynthesis|regulation of Lanosulin biosynthetic process|regulation of Lanosulin biosynthesis|regulation of fumitremorgin B anabolism|regulation of fumitremorgin B synthesis|regulation of Lanosulin anabolism|regulation of fumitremorgin B formation http://purl.obolibrary.org/obo/GO_1900855 GO:1900854 biolink:BiologicalProcess positive regulation of terrequinone A biosynthetic process Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process. go-plus.json upregulation of terrequinone A biosynthetic process|up regulation of terrequinone A biosynthetic process|up-regulation of terrequinone A biosynthetic process http://purl.obolibrary.org/obo/GO_1900854 GO:1900857 biolink:BiologicalProcess positive regulation of fumitremorgin B biosynthetic process Any process that activates or increases the frequency, rate or extent of fumitremorgin B biosynthetic process. go-plus.json up-regulation of fumitremorgin B biosynthetic process|up regulation of fumitremorgin B biosynthetic process|upregulation of fumitremorgin B biosynthetic process http://purl.obolibrary.org/obo/GO_1900857 GO:1900856 biolink:BiologicalProcess negative regulation of fumitremorgin B biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process. go-plus.json down-regulation of fumitremorgin B biosynthetic process|downregulation of fumitremorgin B biosynthetic process|down regulation of fumitremorgin B biosynthetic process http://purl.obolibrary.org/obo/GO_1900856 GO:1900851 biolink:BiologicalProcess positive regulation of pseurotin A biosynthetic process Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process. go-plus.json upregulation of pseurotin A biosynthetic process|up-regulation of pseurotin A biosynthetic process|up regulation of pseurotin A biosynthetic process http://purl.obolibrary.org/obo/GO_1900851 GO:1900850 biolink:BiologicalProcess negative regulation of pseurotin A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process. go-plus.json down regulation of pseurotin A biosynthetic process|down-regulation of pseurotin A biosynthetic process|downregulation of pseurotin A biosynthetic process http://purl.obolibrary.org/obo/GO_1900850 GO:1900853 biolink:BiologicalProcess negative regulation of terrequinone A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of terrequinone A biosynthetic process. go-plus.json down regulation of terrequinone A biosynthetic process|downregulation of terrequinone A biosynthetic process|down-regulation of terrequinone A biosynthetic process http://purl.obolibrary.org/obo/GO_1900853 GO:1900852 biolink:BiologicalProcess regulation of terrequinone A biosynthetic process Any process that modulates the frequency, rate or extent of terrequinone A biosynthetic process. go-plus.json regulation of terrequinone A synthesis|regulation of terrequinone A biosynthesis|regulation of terrequinone A formation|regulation of terrequinone A anabolism http://purl.obolibrary.org/obo/GO_1900852 CHEBI:35552 biolink:ChemicalSubstance heterocyclic organic fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35552 CHEBI:35555 biolink:ChemicalSubstance mancude organic heteromonocyclic parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35555 CHEBI:35554 biolink:ChemicalSubstance cardiovascular drug go-plus.json http://purl.obolibrary.org/obo/CHEBI_35554 CHEBI:35557 biolink:ChemicalSubstance 3H-pyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35557 CHEBI:35556 biolink:ChemicalSubstance pyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35556 GO:0071989 biolink:BiologicalProcess establishment of protein localization to spindle pole body The directed movement of a protein to a specific location at the spindle pole body. go-plus.json establishment of protein localisation to spindle pole body http://purl.obolibrary.org/obo/GO_0071989 CHEBI:35559 biolink:ChemicalSubstance furan go-plus.json http://purl.obolibrary.org/obo/CHEBI_35559 chebi_ph7_3 GO:0071988 biolink:BiologicalProcess protein localization to spindle pole body A process in which a protein is transported to, or maintained at, the spindle pole body. go-plus.json protein localisation to spindle pole body http://purl.obolibrary.org/obo/GO_0071988 CHEBI:35558 biolink:ChemicalSubstance 2H-pyrrole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35558 GO:0071987 biolink:MolecularActivity WD40-repeat domain binding Binding to a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain. go-plus.json WD domain binding|beta-transducin repeat domain binding http://purl.obolibrary.org/obo/GO_0071987 GO:0071986 biolink:CellularComponent Ragulator complex A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signalling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified). go-plus.json Rag GEF|MAPKSP1/ROBLD3/C11orf59 complex|EGO complex|GTPase-containing complex for Gap1p sorting in the endosome|EGO-GSE complex|GSE complex http://purl.obolibrary.org/obo/GO_0071986 GO:0071985 biolink:BiologicalProcess multivesicular body sorting pathway A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded. go-plus.json http://purl.obolibrary.org/obo/GO_0071985 GO:0071984 biolink:BiologicalProcess maintenance of reproductive diapause The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0071984 GO:0071983 biolink:BiologicalProcess exit from reproductive diapause The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. go-plus.json http://purl.obolibrary.org/obo/GO_0071983 CHEBI:59524 biolink:ChemicalSubstance lipoarabinomannan go-plus.json http://purl.obolibrary.org/obo/CHEBI_59524 GO:0071982 biolink:BiologicalProcess maintenance of diapause The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation. go-plus.json http://purl.obolibrary.org/obo/GO_0071982 NCBITaxon:8089 biolink:OrganismalEntity Oryzias go-plus.json Xenopoecilus http://purl.obolibrary.org/obo/NCBITaxon_8089 NCBITaxon:8088 biolink:OrganismalEntity Oryziinae go-plus.json ricefishes|Oryziatinae|medakas http://purl.obolibrary.org/obo/NCBITaxon_8088 GO:0071981 biolink:BiologicalProcess exit from diapause The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation. go-plus.json http://purl.obolibrary.org/obo/GO_0071981 GO:0071980 biolink:BiologicalProcess cell surface adhesin-mediated gliding motility Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0071980 CHEBI:35550 biolink:ChemicalSubstance 1H-1,2,4-triazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35550 chebi_ph7_3 GO:1900869 biolink:BiologicalProcess tatiopterin metabolic process The chemical reactions and pathways involving tatiopterin. go-plus.json tatiopterin metabolism http://purl.obolibrary.org/obo/GO_1900869 GO:0007309 biolink:BiologicalProcess oocyte axis specification The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster. go-plus.json oocyte axis determination http://purl.obolibrary.org/obo/GO_0007309 GO:0007308 biolink:BiologicalProcess oocyte construction The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. go-plus.json oocyte arrangement http://purl.obolibrary.org/obo/GO_0007308 GO:0007307 biolink:BiologicalProcess eggshell chorion gene amplification Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster. go-plus.json http://purl.obolibrary.org/obo/GO_0007307 GO:1900866 biolink:BiologicalProcess glycolate transport The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_1900866 GO:0007306 biolink:BiologicalProcess eggshell chorion assembly Construction of the chorion portion of the eggshell, which comprises the channels for gas exchange in an insect eggshell. go-plus.json eggshell chorion formation|insect chorion formation http://purl.obolibrary.org/obo/GO_0007306 GO:1900865 biolink:BiologicalProcess chloroplast RNA modification Any RNA modification that takes place in chloroplast. go-plus.json RNA editing in chloroplast http://purl.obolibrary.org/obo/GO_1900865 GO:0007305 biolink:BiologicalProcess vitelline membrane formation involved in chorion-containing eggshell formation Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. go-plus.json vitelline membrane formation in chorion-containing eggshell http://purl.obolibrary.org/obo/GO_0007305 GO:0007304 biolink:BiologicalProcess chorion-containing eggshell formation The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. go-plus.json eggshell formation http://purl.obolibrary.org/obo/GO_0007304 GO:1900868 biolink:BiologicalProcess sarcinapterin biosynthetic process The chemical reactions and pathways resulting in the formation of sarcinapterin. go-plus.json sarcinapterin formation|sarcinapterin biosynthesis|sarcinapterin anabolism|sarcinapterin synthesis http://purl.obolibrary.org/obo/GO_1900868 GO:0007303 biolink:BiologicalProcess cytoplasmic transport, nurse cell to oocyte The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0007303 GO:1900867 biolink:BiologicalProcess sarcinapterin metabolic process The chemical reactions and pathways involving sarcinapterin. go-plus.json sarcinapterin metabolism http://purl.obolibrary.org/obo/GO_1900867 GO:1900862 biolink:BiologicalProcess negative regulation of cordyol C biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process. go-plus.json down regulation of cordyol C biosynthetic process|down-regulation of cordyol C biosynthetic process|downregulation of cordyol C biosynthetic process http://purl.obolibrary.org/obo/GO_1900862 GO:0007302 biolink:BiologicalProcess nurse cell nucleus anchoring Attachment of the nurse cell nucleus to the plasma membrane. go-plus.json http://purl.obolibrary.org/obo/GO_0007302 GO:0007301 biolink:BiologicalProcess female germline ring canal formation Assembly of the intercellular bridges that connect the germ-line cells of a female cyst. go-plus.json ovarian ring canal formation|nurse cell ring canal formation http://purl.obolibrary.org/obo/GO_0007301 GO:1900861 biolink:BiologicalProcess regulation of cordyol C biosynthetic process Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process. go-plus.json http://purl.obolibrary.org/obo/GO_1900861 GO:0007300 biolink:BiologicalProcess ovarian nurse cell to oocyte transport Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster. go-plus.json nurse cell to oocyte transport http://purl.obolibrary.org/obo/GO_0007300 GO:1900864 biolink:BiologicalProcess mitochondrial RNA modification Any RNA modification that takes place in mitochondrion. go-plus.json mitochondrial RNA editing http://purl.obolibrary.org/obo/GO_1900864 GO:1900863 biolink:BiologicalProcess positive regulation of cordyol C biosynthetic process Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process. go-plus.json upregulation of cordyol C biosynthetic process|up-regulation of cordyol C biosynthetic process|activation of cordyol C biosynthetic process|up regulation of cordyol C biosynthetic process http://purl.obolibrary.org/obo/GO_1900863 GO:1900860 biolink:BiologicalProcess positive regulation of brevianamide F biosynthetic process Any process that activates or increases the frequency, rate or extent of brevianamide F biosynthetic process. go-plus.json up-regulation of brevianamide F biosynthetic process|upregulation of brevianamide F biosynthetic process|up regulation of brevianamide F biosynthetic process http://purl.obolibrary.org/obo/GO_1900860 CHEBI:35568 biolink:ChemicalSubstance mancude ring go-plus.json http://purl.obolibrary.org/obo/CHEBI_35568 GO:0071979 biolink:BiologicalProcess cytoskeleton-mediated cell swimming Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium. go-plus.json cytoskeleton-mediated swimming motility http://purl.obolibrary.org/obo/GO_0071979 GO:0071978 biolink:BiologicalProcess bacterial-type flagellum-dependent swarming motility Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria. go-plus.json bacterial-type flagellar swarming motility|bacterial-type flagellum-mediated cell swarming http://purl.obolibrary.org/obo/GO_0071978 NCBITaxon:8090 biolink:OrganismalEntity Oryzias latipes go-plus.json medaka|Poecilia latipes|Japanese medaka|Japanese rice fish http://purl.obolibrary.org/obo/NCBITaxon_8090 GO:0071977 biolink:BiologicalProcess bacterial-type flagellum-dependent swimming motility Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium. go-plus.json bacterial-type flagellum-mediated cell swimming|bacterial-type flagellar swimming motility http://purl.obolibrary.org/obo/GO_0071977 CHEBI:35569 biolink:ChemicalSubstance alpha-adrenergic agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_35569 GO:0071976 biolink:BiologicalProcess cell gliding Cell motility that results in the smooth movement of a cell along a solid surface. go-plus.json cell gliding motility http://purl.obolibrary.org/obo/GO_0071976 CHEBI:59517 biolink:ChemicalSubstance DNA synthesis inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_59517 GO:0071975 biolink:BiologicalProcess cell swimming Cell motility that results in the smooth movement of a cell through a liquid medium. go-plus.json cell swimming motility http://purl.obolibrary.org/obo/GO_0071975 GO:0071974 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071974 GO:0071973 biolink:BiologicalProcess bacterial-type flagellum-dependent cell motility Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. go-plus.json bacterial-type flagellar cell motility|flagellin-based flagellar cell motility http://purl.obolibrary.org/obo/GO_0071973 goslim_metagenomics GO:0071972 biolink:MolecularActivity peptidoglycan L,D-transpeptidase activity Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine. MetaCyc:RXN-11349 go-plus.json http://purl.obolibrary.org/obo/GO_0071972 CHEBI:35560 biolink:ChemicalSubstance 1,2,4-triazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35560 CHEBI:59513 biolink:ChemicalSubstance monodehydro-L-ascorbate(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59513 chebi_ph7_3 GO:0071971 biolink:BiologicalProcess extracellular exosome assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. go-plus.json extracellular vesicular exosome assembly http://purl.obolibrary.org/obo/GO_0071971 GO:0071970 biolink:BiologicalProcess fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls. go-plus.json fungal-type cell wall 1,3-beta-glucan formation|fungal-type cell wall 1,3-beta-glucan biosynthesis|fungal-type cell wall beta-1,3-glucan anabolism|fungal-type cell wall 1,3-beta-D-glucan biosynthetic process|fungal-type cell wall beta-1,3-glucan synthesis|fungal-type cell wall beta-1,3-glucan formation|fungal-type cell wall beta-1,3-glucan biosynthetic process|fungal-type cell wall beta-1,3-glucan biosynthesis|fungal-type cell wall 1,3-beta-glucan anabolism|fungal-type cell wall 1,3-beta-glucan synthesis http://purl.obolibrary.org/obo/GO_0071970 CHEBI:35561 biolink:ChemicalSubstance 3H-1,2,4-triazole go-plus.json http://purl.obolibrary.org/obo/CHEBI_35561 chebi_ph7_3 GO:0032393 biolink:MolecularActivity MHC class I receptor activity Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules. go-plus.json gamma-delta T cell receptor activity|alpha-beta T cell receptor activity|T cell receptor activity http://purl.obolibrary.org/obo/GO_0032393 GO:0032392 biolink:BiologicalProcess DNA geometric change The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases. go-plus.json http://purl.obolibrary.org/obo/GO_0032392 goslim_pir GO:0032391 biolink:CellularComponent photoreceptor connecting cilium The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone. go-plus.json photoreceptor cilium http://purl.obolibrary.org/obo/GO_0032391 GO:0032390 biolink:CellularComponent MutLbeta complex A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1. go-plus.json MLH1/PMS1 complex|MMR complex http://purl.obolibrary.org/obo/GO_0032390 GO:0032399 biolink:MolecularActivity HECT domain binding Binding to a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0032399 GO:0032398 biolink:CellularComponent MHC class Ib protein complex A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. go-plus.json http://purl.obolibrary.org/obo/GO_0032398 GO:0032397 biolink:MolecularActivity activating MHC class I receptor activity Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0032397 GO:0032396 biolink:MolecularActivity inhibitory MHC class I receptor activity Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte. go-plus.json http://purl.obolibrary.org/obo/GO_0032396 GO:0032395 biolink:MolecularActivity MHC class II receptor activity Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. go-plus.json gamma-delta T cell receptor activity|alpha-beta T cell receptor activity|T cell receptor activity http://purl.obolibrary.org/obo/GO_0032395 GO:0032394 biolink:MolecularActivity MHC class Ib receptor activity Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. go-plus.json gamma-delta T cell receptor activity|alpha-beta T cell receptor activity|T cell receptor activity http://purl.obolibrary.org/obo/GO_0032394 GO:0032382 biolink:BiologicalProcess positive regulation of intracellular sterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells. go-plus.json up regulation of intracellular sterol transport|upregulation of intracellular sterol transport|stimulation of intracellular sterol transport|up-regulation of intracellular sterol transport|activation of intracellular sterol transport http://purl.obolibrary.org/obo/GO_0032382 GO:0032381 biolink:BiologicalProcess negative regulation of intracellular sterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells. go-plus.json downregulation of intracellular sterol transport|down regulation of intracellular sterol transport|inhibition of intracellular sterol transport|down-regulation of intracellular sterol transport http://purl.obolibrary.org/obo/GO_0032381 GO:0032380 biolink:BiologicalProcess regulation of intracellular sterol transport Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032380 GO:0032389 biolink:CellularComponent MutLalpha complex A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2. go-plus.json MutL-alpha complex|MMR complex|MLH1/PMS2 complex http://purl.obolibrary.org/obo/GO_0032389 GO:0032388 biolink:BiologicalProcess positive regulation of intracellular transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. go-plus.json upregulation of intracellular transport|up regulation of intracellular transport|activation of intracellular transport|stimulation of intracellular transport|up-regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0032388 GO:0032387 biolink:BiologicalProcess negative regulation of intracellular transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. go-plus.json down regulation of intracellular transport|downregulation of intracellular transport|down-regulation of intracellular transport|inhibition of intracellular transport http://purl.obolibrary.org/obo/GO_0032387 GO:0032386 biolink:BiologicalProcess regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032386 GO:0032385 biolink:BiologicalProcess positive regulation of intracellular cholesterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells. go-plus.json up regulation of intracellular cholesterol transport|activation of intracellular cholesterol transport|stimulation of intracellular cholesterol transport|up-regulation of intracellular cholesterol transport|upregulation of intracellular cholesterol transport http://purl.obolibrary.org/obo/GO_0032385 GO:0032384 biolink:BiologicalProcess negative regulation of intracellular cholesterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells. go-plus.json down-regulation of intracellular cholesterol transport|inhibition of intracellular cholesterol transport|down regulation of intracellular cholesterol transport|downregulation of intracellular cholesterol transport http://purl.obolibrary.org/obo/GO_0032384 GO:0032383 biolink:BiologicalProcess regulation of intracellular cholesterol transport Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032383 GO:0046907 biolink:BiologicalProcess intracellular transport The directed movement of substances within a cell. go-plus.json single organism intracellular transport|single-organism intracellular transport http://purl.obolibrary.org/obo/GO_0046907 CHEBI:60520 biolink:ChemicalSubstance 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60520 chebi_ph7_3 GO:0032371 biolink:BiologicalProcess regulation of sterol transport Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032371 GO:0032370 biolink:BiologicalProcess positive regulation of lipid transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up-regulation of lipid transport|upregulation of lipid transport|up regulation of lipid transport|activation of lipid transport|stimulation of lipid transport http://purl.obolibrary.org/obo/GO_0032370 GO:0046906 biolink:MolecularActivity tetrapyrrole binding Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position. go-plus.json porphyrin binding http://purl.obolibrary.org/obo/GO_0046906 goslim_pir|goslim_metagenomics GO:0046905 biolink:MolecularActivity 15-cis-phytoene synthase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate. RHEA:34479 go-plus.json phytoene synthase activity http://purl.obolibrary.org/obo/GO_0046905 CHEBI:60522 biolink:ChemicalSubstance phosphatidylglycerol phosphate(3-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60522 chebi_ph7_3 GO:0046904 biolink:MolecularActivity calcium oxalate binding Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi. go-plus.json http://purl.obolibrary.org/obo/GO_0046904 CHEBI:60521 biolink:ChemicalSubstance indole alkaloid cation go-plus.json http://purl.obolibrary.org/obo/CHEBI_60521 GO:0046903 biolink:BiologicalProcess secretion The controlled release of a substance by a cell or a tissue. go-plus.json http://purl.obolibrary.org/obo/GO_0046903 goslim_pir CHEBI:60524 biolink:ChemicalSubstance 3-O-L-alanyl-1-O-phosphatidylglycerol zwitterion go-plus.json http://purl.obolibrary.org/obo/CHEBI_60524 chebi_ph7_3 GO:0046902 biolink:BiologicalProcess regulation of mitochondrial membrane permeability Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. go-plus.json regulation of transport across mitochondrial membrane|regulation of mitochondrial envelope permeability http://purl.obolibrary.org/obo/GO_0046902 CHEBI:60523 biolink:ChemicalSubstance phosphatidylglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60523 chebi_ph7_3 GO:0046901 biolink:BiologicalProcess tetrahydrofolylpolyglutamate biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues. go-plus.json THF polyglutamylation|tetrahydrofolate polyglutamylation|tetrahydrofolyl-[Glu](n) biosynthesis|tetrahydrofolyl-[Glu](n) biosynthetic process|tetrahydrofolylpolyglutamate anabolism|folic acid-containing compound polyglutamylation|tetrahydrofolylpolyglutamate synthesis|tetrahydrofolylpolyglutamate formation|tetrahydrofolylpolyglutamate biosynthesis http://purl.obolibrary.org/obo/GO_0046901 GO:0046900 biolink:BiologicalProcess tetrahydrofolylpolyglutamate metabolic process The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues. go-plus.json tetrahydrofolylpolyglutamate metabolism|tetrahydrofolyl-[Glu](n) metabolism|tetrahydrofolyl-[Glu](n) metabolic process http://purl.obolibrary.org/obo/GO_0046900 GO:0032379 biolink:BiologicalProcess positive regulation of intracellular lipid transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. go-plus.json up-regulation of intracellular lipid transport|upregulation of intracellular lipid transport|up regulation of intracellular lipid transport|activation of intracellular lipid transport|stimulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032379 GO:0032378 biolink:BiologicalProcess negative regulation of intracellular lipid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. go-plus.json inhibition of intracellular lipid transport|down regulation of intracellular lipid transport|downregulation of intracellular lipid transport|down-regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032378 GO:0032377 biolink:BiologicalProcess regulation of intracellular lipid transport Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032377 GO:0032376 biolink:BiologicalProcess positive regulation of cholesterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json up-regulation of cholesterol transport|upregulation of cholesterol transport|up regulation of cholesterol transport|activation of cholesterol transport|stimulation of cholesterol transport http://purl.obolibrary.org/obo/GO_0032376 CHEBI:60529 biolink:ChemicalSubstance ergoline alkaloid go-plus.json http://purl.obolibrary.org/obo/CHEBI_60529 GO:0032375 biolink:BiologicalProcess negative regulation of cholesterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down-regulation of cholesterol transport|inhibition of cholesterol transport|down regulation of cholesterol transport|downregulation of cholesterol transport http://purl.obolibrary.org/obo/GO_0032375 GO:0032374 biolink:BiologicalProcess regulation of cholesterol transport Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032374 GO:0032373 biolink:BiologicalProcess positive regulation of sterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json activation of sterol transport|up regulation of sterol transport|upregulation of sterol transport|stimulation of sterol transport|up-regulation of sterol transport http://purl.obolibrary.org/obo/GO_0032373 GO:0046909 biolink:BiologicalProcess obsolete intermembrane transport OBSOLETE. The directed movement of substances between any membrane of a cell, including the plasma membrane and its regions. go-plus.json http://purl.obolibrary.org/obo/GO_0046909 GO:0046908 biolink:BiologicalProcess obsolete negative regulation of crystal formation OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the spontaneous (nonenzymatic) formation of crystals in a solution, for example, calcium oxalate crystals in urine. go-plus.json negative regulation of crystal formation|negative regulation of mineralization http://purl.obolibrary.org/obo/GO_0046908 GO:0032372 biolink:BiologicalProcess negative regulation of sterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down-regulation of sterol transport|downregulation of sterol transport|down regulation of sterol transport|inhibition of sterol transport http://purl.obolibrary.org/obo/GO_0032372 GO:0032369 biolink:BiologicalProcess negative regulation of lipid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json down regulation of lipid transport|downregulation of lipid transport|down-regulation of lipid transport|inhibition of lipid transport http://purl.obolibrary.org/obo/GO_0032369 GO:0046910 biolink:MolecularActivity pectinesterase inhibitor activity Binds to and stops, prevents or reduces the activity of pectinesterase. go-plus.json http://purl.obolibrary.org/obo/GO_0046910 GO:0046918 biolink:BiologicalProcess N-terminal peptidyl-glycine N-palmitoylation The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine. RESID:AA0339 go-plus.json http://purl.obolibrary.org/obo/GO_0046918 GO:0032360 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032360 CHEBI:60531 biolink:ChemicalSubstance flavin(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60531 chebi_ph7_3 GO:0046917 biolink:MolecularActivity triphosphoribosyl-dephospho-CoA synthase activity Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine. MetaCyc:2.7.8.25-RXN|EC:2.4.2.52|RHEA:15117 go-plus.json 2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity|CitG activity|ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity|ATP:dephospho-CoA 5-triphosphoribosyl transferase activity http://purl.obolibrary.org/obo/GO_0046917 CHEBI:60530 biolink:ChemicalSubstance ferroheme o(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60530 chebi_ph7_3 GO:0046916 biolink:BiologicalProcess cellular transition metal ion homeostasis Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. go-plus.json http://purl.obolibrary.org/obo/GO_0046916 GO:0046915 biolink:MolecularActivity transition metal ion transmembrane transporter activity Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. go-plus.json http://purl.obolibrary.org/obo/GO_0046915 GO:0046914 biolink:MolecularActivity transition metal ion binding Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. go-plus.json http://purl.obolibrary.org/obo/GO_0046914 GO:0046913 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046913 GO:0046912 biolink:MolecularActivity acyltransferase, acyl groups converted into alkyl on transfer Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer. EC:2.3.3.- go-plus.json transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer http://purl.obolibrary.org/obo/GO_0046912 GO:0046911 biolink:MolecularActivity metal chelating activity The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring. go-plus.json metal chelation|heavy metal chelation http://purl.obolibrary.org/obo/GO_0046911 GO:0032368 biolink:BiologicalProcess regulation of lipid transport Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032368 GO:0032367 biolink:BiologicalProcess intracellular cholesterol transport The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032367 GO:0032366 biolink:BiologicalProcess intracellular sterol transport The directed movement of sterols within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032366 GO:0032365 biolink:BiologicalProcess intracellular lipid transport The directed movement of lipids within cells. go-plus.json http://purl.obolibrary.org/obo/GO_0032365 GO:0032364 biolink:BiologicalProcess oxygen homeostasis A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell. go-plus.json http://purl.obolibrary.org/obo/GO_0032364 GO:0032363 biolink:BiologicalProcess FMN catabolic process The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase. go-plus.json http://purl.obolibrary.org/obo/GO_0032363 GO:0032362 biolink:BiologicalProcess obsolete FAD catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide. go-plus.json FAD breakdown|FAD catabolism|oxidized flavin adenine dinucleotide catabolic process|FAD degradation http://purl.obolibrary.org/obo/GO_0032362 GO:0032361 biolink:BiologicalProcess pyridoxal phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6. go-plus.json http://purl.obolibrary.org/obo/GO_0032361 GO:0046919 biolink:MolecularActivity pyruvyltransferase activity Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another. go-plus.json http://purl.obolibrary.org/obo/GO_0046919 CHEBI:84509 biolink:ChemicalSubstance 2-all-trans-heptaprenylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84509 chebi_ph7_3 GO:0032359 biolink:BiologicalProcess provirus excision The molecular events that lead to the excision of a viral genome from the host genome. go-plus.json prophage excision http://purl.obolibrary.org/obo/GO_0032359 GO:0032358 biolink:MolecularActivity oxidized pyrimidine DNA binding Binding to a DNA region containing an oxidized pyrimidine residue. go-plus.json oxidized pyrimidine base DNA binding|oxidised pyrimidine DNA binding|oxidized pyrimidine nucleobase DNA binding http://purl.obolibrary.org/obo/GO_0032358 GO:0046921 biolink:MolecularActivity alpha-(1->6)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage. go-plus.json alpha(1,6)-fucosyltransferase activity|alpha-1,6-fucosyltransferase activity|alpha-(1,6)-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0046921 GO:0046920 biolink:MolecularActivity alpha-(1->3)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage. Reactome:R-HSA-9605644|Reactome:R-HSA-9605609|Reactome:R-HSA-9605682|Reactome:R-HSA-9603984 go-plus.json alpha(1,3)-fucosyltransferase activity|alpha-(1,3)-fucosyltransferase activity|alpha-1,3-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0046920 GO:0007399 biolink:BiologicalProcess nervous system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. go-plus.json pan-neural process http://purl.obolibrary.org/obo/GO_0007399 goslim_drosophila GO:0007398 biolink:BiologicalProcess ectoderm development The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. go-plus.json http://purl.obolibrary.org/obo/GO_0007398 CHEBI:84503 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-decaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84503 chebi_ph7_3 CHEBI:84502 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-nonaprenylbenzoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_84502 chebi_ph7_3 GO:0007397 biolink:BiologicalProcess obsolete histogenesis and organogenesis OBSOLETE. The generation of organized tissues or of whole organs. go-plus.json histogenesis and organogenesis http://purl.obolibrary.org/obo/GO_0007397 GO:0007396 biolink:BiologicalProcess suture of dorsal opening Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole. go-plus.json http://purl.obolibrary.org/obo/GO_0007396 CHEBI:84501 biolink:ChemicalSubstance 4-hydroxy-3-all-trans-nonaprenylbenzoic acid go-plus.json http://purl.obolibrary.org/obo/CHEBI_84501 GO:0007395 biolink:BiologicalProcess dorsal closure, spreading of leading edge cells Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa. go-plus.json http://purl.obolibrary.org/obo/GO_0007395 CHEBI:60540 biolink:ChemicalSubstance coenzyme F430(5-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60540 chebi_ph7_3 GO:0007394 biolink:BiologicalProcess dorsal closure, elongation of leading edge cells The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis. go-plus.json http://purl.obolibrary.org/obo/GO_0007394 GO:0046929 biolink:BiologicalProcess negative regulation of neurotransmitter secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. go-plus.json down-regulation of neurotransmitter secretion|downregulation of neurotransmitter secretion|conotoxin activity|down regulation of neurotransmitter secretion|inhibition of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0046929 GO:0046928 biolink:BiologicalProcess regulation of neurotransmitter secretion Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0046928 GO:0046927 biolink:BiologicalProcess peptidyl-threonine racemization The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine. go-plus.json http://purl.obolibrary.org/obo/GO_0046927 GO:0046926 biolink:BiologicalProcess peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine. RESID:AA0342 go-plus.json http://purl.obolibrary.org/obo/GO_0046926 GO:0046925 biolink:BiologicalProcess peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine. RESID:AA0341 go-plus.json http://purl.obolibrary.org/obo/GO_0046925 GO:0046924 biolink:BiologicalProcess peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine. RESID:AA0340 go-plus.json http://purl.obolibrary.org/obo/GO_0046924 OIO:inSubset biolink:OntologyClass in_subset go-plus.json http://www.geneontology.org/formats/oboInOwl#inSubset GO:0046923 biolink:MolecularActivity ER retention sequence binding Binding to an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER. go-plus.json endoplasmic reticulum retention sequence binding http://purl.obolibrary.org/obo/GO_0046923 GO:0046922 biolink:MolecularActivity peptide-O-fucosyltransferase activity Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor. MetaCyc:2.4.1.221-RXN|EC:2.4.1.221|Reactome:R-HSA-5173192|Reactome:R-HSA-1912349 go-plus.json GDP-fucose protein O-fucosyltransferase activity|GDP-L-fucose:polypeptide fucosyltransferase activity|GDP-fucose:polypeptide fucosyltransferase activity|GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity http://purl.obolibrary.org/obo/GO_0046922 GO:0032357 biolink:MolecularActivity oxidized purine DNA binding Binding to a DNA region containing an oxidized purine residue. go-plus.json oxidized purine base DNA binding|oxidized purine nucleobase DNA binding|oxidised purine DNA binding http://purl.obolibrary.org/obo/GO_0032357 GO:0032356 biolink:MolecularActivity oxidized DNA binding Binding to a DNA region containing an oxidized residue. go-plus.json oxidised DNA binding http://purl.obolibrary.org/obo/GO_0032356 CHEBI:60549 biolink:ChemicalSubstance ferroheme d1(4-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_60549 chebi_ph7_3 GO:0032355 biolink:BiologicalProcess response to estradiol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. go-plus.json response to estradiol stimulus|response to E2 stimulus http://purl.obolibrary.org/obo/GO_0032355 GO:0032354 biolink:BiologicalProcess response to follicle-stimulating hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus. go-plus.json response to follicle-stimulating hormone stimulus|response to FSH stimulus|response to follicle stimulating hormone stimulus http://purl.obolibrary.org/obo/GO_0032354 GO:0032353 biolink:BiologicalProcess negative regulation of hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. go-plus.json down regulation of hormone biosynthetic process|inhibition of hormone biosynthetic process|down-regulation of hormone biosynthetic process|downregulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0032353 GO:0032352 biolink:BiologicalProcess positive regulation of hormone metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. go-plus.json upregulation of hormone metabolic process|up regulation of hormone metabolic process|activation of hormone metabolic process|stimulation of hormone metabolic process|up-regulation of hormone metabolic process|positive regulation of hormone metabolism http://purl.obolibrary.org/obo/GO_0032352 GO:0032351 biolink:BiologicalProcess negative regulation of hormone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. go-plus.json down regulation of hormone metabolic process|downregulation of hormone metabolic process|down-regulation of hormone metabolic process|negative regulation of hormone metabolism|inhibition of hormone metabolic process http://purl.obolibrary.org/obo/GO_0032351 GO:0032350 biolink:BiologicalProcess regulation of hormone metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. go-plus.json regulation of hormone metabolism http://purl.obolibrary.org/obo/GO_0032350 GO:0032349 biolink:BiologicalProcess positive regulation of aldosterone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. go-plus.json activation of aldosterone biosynthetic process|up-regulation of aldosterone biosynthetic process|up regulation of aldosterone biosynthetic process|upregulation of aldosterone biosynthetic process|stimulation of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0032349 GO:0032348 biolink:BiologicalProcess negative regulation of aldosterone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. go-plus.json down-regulation of aldosterone biosynthetic process|downregulation of aldosterone biosynthetic process|down regulation of aldosterone biosynthetic process|inhibition of aldosterone biosynthetic process http://purl.obolibrary.org/obo/GO_0032348 GO:0032347 biolink:BiologicalProcess regulation of aldosterone biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. go-plus.json http://purl.obolibrary.org/obo/GO_0032347 CHEBI:84518 biolink:ChemicalSubstance 3-(all-trans-decaprenyl)benzene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84518 chebi_ph7_3 GO:0046932 biolink:MolecularActivity sodium-transporting ATP synthase activity, rotational mechanism Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism. EC:7.2.2.1|RHEA:58158|TC:3.A.2.1.2|MetaCyc:3.6.3.15-RXN|RHEA:58156 go-plus.json sodium-translocating F-type ATPase activity|sodium-transporting two-sector ATPase activity http://purl.obolibrary.org/obo/GO_0046932 CHEBI:84517 biolink:ChemicalSubstance 3-(all-trans-nonaprenyl)benzene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84517 chebi_ph7_3 GO:0046931 biolink:BiologicalProcess pore complex assembly The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases. go-plus.json pore complex biogenesis|pore-forming toxin activity|pore formation|pore biosynthesis http://purl.obolibrary.org/obo/GO_0046931 CHEBI:84516 biolink:ChemicalSubstance 3-(all-trans-heptaprenyl)benzene-1,2-diol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84516 chebi_ph7_3 GO:0046930 biolink:CellularComponent pore complex A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids. go-plus.json channel-forming toxin activity|pore|pore-forming toxin activity http://purl.obolibrary.org/obo/GO_0046930 CHEBI:84515 biolink:ChemicalSubstance sn-glycero-3-phosphoglycerol(1-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84515 chebi_ph7_3 PR:000006013 biolink:Protein catenin delta-2 A protein that is a translation product of the human CTNND2 gene or a 1:1 ortholog thereof. go-plus.json CTNND2|NPRAP|delta-catenin|GT24|neural plakophilin-related ARM-repeat protein|neurojungin|Catnd2 http://purl.obolibrary.org/obo/PR_000006013 CHEBI:84513 biolink:ChemicalSubstance 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_84513 CHEBI:84511 biolink:ChemicalSubstance 2-all-trans-decaprenylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84511 chebi_ph7_3 CHEBI:142880 biolink:ChemicalSubstance 7,2'-dihydroxy-4'-methoxyisoflavanol go-plus.json http://purl.obolibrary.org/obo/CHEBI_142880 chebi_ph7_3 CHEBI:84510 biolink:ChemicalSubstance 2-all-trans-nonaprenylphenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84510 chebi_ph7_3 GO:0046939 biolink:BiologicalProcess nucleotide phosphorylation The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside. go-plus.json http://purl.obolibrary.org/obo/GO_0046939 GO:0046938 biolink:BiologicalProcess phytochelatin biosynthetic process The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11. go-plus.json phytochelatin anabolism|phytochelatin synthesis|phytochelatin formation|phytochelatin biosynthesis|cadystin biosynthetic process http://purl.obolibrary.org/obo/GO_0046938 GO:0046937 biolink:BiologicalProcess phytochelatin metabolic process The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11. go-plus.json cadystin metabolism|phytochelatin metabolism|cadystin metabolic process http://purl.obolibrary.org/obo/GO_0046937 GO:0046936 biolink:MolecularActivity 2'-deoxyadenosine deaminase activity Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3. MetaCyc:ADDALT-RXN|RHEA:28190 go-plus.json deoxyadenosine deaminase reaction http://purl.obolibrary.org/obo/GO_0046936 GO:0046935 biolink:MolecularActivity 1-phosphatidylinositol-3-kinase regulator activity Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity. go-plus.json 1-phosphatidylinositol 3-kinase regulator activity|phosphatidylinositol 3-kinase, class I, regulator activity http://purl.obolibrary.org/obo/GO_0046935 GO:0046934 biolink:MolecularActivity phosphatidylinositol-4,5-bisphosphate 3-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+). Reactome:R-HSA-5654697|Reactome:R-HSA-2394007|Reactome:R-HSA-5654709|Reactome:R-HSA-9665407|Reactome:R-HSA-2316434|Reactome:R-HSA-1676048|Reactome:R-HSA-389158|Reactome:R-HSA-177939|Reactome:R-HSA-202365|Reactome:R-HSA-5654692|Reactome:R-HSA-9021627|Reactome:R-HSA-5654717|Reactome:R-HSA-5654705|Reactome:R-HSA-5637801|Reactome:R-HSA-5654714|Reactome:R-HSA-2424480|Reactome:R-HSA-2730870|Reactome:R-HSA-2029271|KEGG_REACTION:R04545|Reactome:R-HSA-5654701|Reactome:R-HSA-1839091|Reactome:R-HSA-5655235|Reactome:R-HSA-198266|MetaCyc:2.7.1.153-RXN|Reactome:R-HSA-1226014|Reactome:R-HSA-5655323|Reactome:R-HSA-9603445|Reactome:R-HSA-5655289|Reactome:R-HSA-5218819|Reactome:R-HSA-1306979|RHEA:21292|EC:2.7.1.153|Reactome:R-HSA-8853323|Reactome:R-HSA-5654690|Reactome:R-HSA-2076220|Reactome:R-HSA-1250462|Reactome:R-HSA-186800|Reactome:R-HSA-392300|Reactome:R-HSA-9664940|Reactome:R-HSA-8852019|Reactome:R-HSA-1306957|Reactome:R-HSA-1839107|Reactome:R-HSA-437162|Reactome:R-HSA-5655290|Reactome:R-HSA-1250370|Reactome:R-HSA-9664664|Reactome:R-HSA-9672177|Reactome:R-HSA-9672162 go-plus.json phosphatidylinositol 3-kinase, class I, catalyst activity|ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity|type I phosphoinositide 3-kinase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase activity, class II http://purl.obolibrary.org/obo/GO_0046934 GO:0046933 biolink:MolecularActivity proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out). RHEA:57720|EC:7.1.2.2|TC:3.A.2.1.1|Reactome:R-HSA-164832|MetaCyc:ATPSYN-RXN go-plus.json hydrogen ion transporting two-sector ATPase activity|H+-transporting ATP synthase activity|hydrogen ion transporting ATP synthase activity, rotational mechanism|hydrogen ion translocating F-type ATPase activity http://purl.obolibrary.org/obo/GO_0046933 GO:0032346 biolink:BiologicalProcess positive regulation of aldosterone metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. go-plus.json up regulation of aldosterone metabolic process|activation of aldosterone metabolic process|stimulation of aldosterone metabolic process|positive regulation of aldosterone metabolism|up-regulation of aldosterone metabolic process|upregulation of aldosterone metabolic process http://purl.obolibrary.org/obo/GO_0032346 GO:0032345 biolink:BiologicalProcess negative regulation of aldosterone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. go-plus.json down-regulation of aldosterone metabolic process|negative regulation of aldosterone metabolism|inhibition of aldosterone metabolic process|down regulation of aldosterone metabolic process|downregulation of aldosterone metabolic process http://purl.obolibrary.org/obo/GO_0032345 GO:0032344 biolink:BiologicalProcess regulation of aldosterone metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. go-plus.json regulation of aldosterone metabolism http://purl.obolibrary.org/obo/GO_0032344 GO:0032343 biolink:BiologicalProcess aldosterone catabolic process The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. go-plus.json http://purl.obolibrary.org/obo/GO_0032343 GO:0032342 biolink:BiologicalProcess aldosterone biosynthetic process The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. go-plus.json http://purl.obolibrary.org/obo/GO_0032342 GO:0032341 biolink:BiologicalProcess aldosterone metabolic process The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. go-plus.json aldosterone metabolism http://purl.obolibrary.org/obo/GO_0032341 GO:0032340 biolink:BiologicalProcess positive regulation of inhibin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell. go-plus.json upregulation of inhibin secretion|up regulation of inhibin secretion|activation of inhibin secretion|stimulation of inhibin secretion|up-regulation of inhibin secretion http://purl.obolibrary.org/obo/GO_0032340 GO:0032339 biolink:BiologicalProcess negative regulation of inhibin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell. go-plus.json down-regulation of inhibin secretion|inhibition of inhibin secretion|down regulation of inhibin secretion|downregulation of inhibin secretion http://purl.obolibrary.org/obo/GO_0032339 GO:0032338 biolink:BiologicalProcess regulation of inhibin secretion Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0032338 GO:0032337 biolink:BiologicalProcess positive regulation of activin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell. go-plus.json stimulation of activin secretion|up-regulation of activin secretion|upregulation of activin secretion|up regulation of activin secretion|activation of activin secretion http://purl.obolibrary.org/obo/GO_0032337 GO:0032336 biolink:BiologicalProcess negative regulation of activin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell. go-plus.json down-regulation of activin secretion|inhibition of activin secretion|down regulation of activin secretion|downregulation of activin secretion http://purl.obolibrary.org/obo/GO_0032336 CHEBI:84529 biolink:ChemicalSubstance 2-methoxy-6-all-trans-nonaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84529 chebi_ph7_3 GO:0046943 biolink:MolecularActivity carboxylic acid transmembrane transporter activity Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). Reactome:R-HSA-390347 go-plus.json http://purl.obolibrary.org/obo/GO_0046943 GO:0007379 biolink:BiologicalProcess segment specification The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes. go-plus.json http://purl.obolibrary.org/obo/GO_0007379 CHEBI:84528 biolink:ChemicalSubstance 2-methoxy-6-all-trans-heptaprenylhydroquinonel go-plus.json http://purl.obolibrary.org/obo/CHEBI_84528 chebi_ph7_3 GO:0007378 biolink:BiologicalProcess amnioserosa formation Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift. go-plus.json http://purl.obolibrary.org/obo/GO_0007378 GO:0046942 biolink:BiologicalProcess carboxylic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). go-plus.json http://purl.obolibrary.org/obo/GO_0046942 GO:0007377 biolink:BiologicalProcess germ-band extension Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further. go-plus.json http://purl.obolibrary.org/obo/GO_0007377 GO:0046941 biolink:MolecularActivity azetidine-2-carboxylic acid acetyltransferase activity Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0046941 GO:0007376 biolink:BiologicalProcess cephalic furrow formation Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome. go-plus.json http://purl.obolibrary.org/obo/GO_0007376 GO:0046940 biolink:BiologicalProcess nucleoside monophosphate phosphorylation The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside. go-plus.json http://purl.obolibrary.org/obo/GO_0046940 GO:0007375 biolink:BiologicalProcess anterior midgut invagination Internalization of the anterior midgut into the interior of the embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0007375 GO:0007374 biolink:BiologicalProcess posterior midgut invagination Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior. go-plus.json http://purl.obolibrary.org/obo/GO_0007374 CHEBI:84522 biolink:ChemicalSubstance 2-methoxy-6-(all-trans-nonaprenyl)phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84522 chebi_ph7_3 GO:0007373 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007373 CHEBI:60562 biolink:ChemicalSubstance ferroheme c go-plus.json http://purl.obolibrary.org/obo/CHEBI_60562 CHEBI:84521 biolink:ChemicalSubstance 2-methoxy-6-(all-trans-heptaprenyl)phenol go-plus.json http://purl.obolibrary.org/obo/CHEBI_84521 chebi_ph7_3 GO:0007372 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0007372 GO:0071907 biolink:BiologicalProcess determination of digestive tract left/right asymmetry Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed. go-plus.json determination of gut left/right asymmetry|determination of left/right asymmetry of the digestive tract http://purl.obolibrary.org/obo/GO_0071907 GO:0007382 biolink:BiologicalProcess specification of segmental identity, maxillary segment The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0007382 GO:0071906 biolink:MolecularActivity CRD domain binding Binding to a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins. go-plus.json context dependent regulatory domain binding http://purl.obolibrary.org/obo/GO_0071906 GO:0007381 biolink:BiologicalProcess specification of segmental identity, labial segment The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0007381 GO:0071905 biolink:BiologicalProcess protein N-linked glucosylation via asparagine A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue. RESID:AA0421 go-plus.json protein amino acid N-linked glucosylation via asparagine http://purl.obolibrary.org/obo/GO_0071905 GO:0007380 biolink:BiologicalProcess specification of segmental identity, head The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0007380 GO:0046949 biolink:BiologicalProcess fatty-acyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. go-plus.json fatty-acyl-CoA anabolism|fatty acyl CoA biosynthetic process|fatty-acyl-CoA biosynthesis|fatty-acyl-CoA synthesis|fatty-acyl-CoA formation http://purl.obolibrary.org/obo/GO_0046949 GO:0071904 biolink:BiologicalProcess protein N-linked N-acetylgalactosaminylation via asparagine A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue. RESID:AA0420 go-plus.json protein amino acid N-linked N-acetylgalactosaminylation via asparagine http://purl.obolibrary.org/obo/GO_0071904 GO:0046948 biolink:BiologicalProcess hydroxylysine catabolic process The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. go-plus.json hydroxylysine catabolism|hydroxylysine degradation|hydroxylysine breakdown http://purl.obolibrary.org/obo/GO_0046948 GO:0071903 biolink:BiologicalProcess protein N-linked N-acetylglucosaminylation via asparagine A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue. RESID:AA0151 go-plus.json protein amino acid N-linked N-acetylglucosaminylation via asparagine http://purl.obolibrary.org/obo/GO_0071903 CHEBI:60568 biolink:ChemicalSubstance 1,2-dioleoyl-sn-glycero-3-phospho-L-serine go-plus.json http://purl.obolibrary.org/obo/CHEBI_60568 GO:0046947 biolink:BiologicalProcess hydroxylysine biosynthetic process The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. go-plus.json hydroxylysine anabolism|hydroxylysine biosynthesis|hydroxylysine synthesis|hydroxylysine formation http://purl.obolibrary.org/obo/GO_0046947 GO:0071902 biolink:BiologicalProcess positive regulation of protein serine/threonine kinase activity Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0071902 GO:0046946 biolink:BiologicalProcess hydroxylysine metabolic process The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases. go-plus.json hydroxylysine metabolism http://purl.obolibrary.org/obo/GO_0046946 GO:0071901 biolink:BiologicalProcess negative regulation of protein serine/threonine kinase activity Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0071901 GO:0046945 biolink:BiologicalProcess N-terminal peptidyl-alanine N-carbamoylation The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine. RESID:AA0343 go-plus.json N-terminal peptidyl-alanine N-carbamylation http://purl.obolibrary.org/obo/GO_0046945 GO:0071900 biolink:BiologicalProcess regulation of protein serine/threonine kinase activity Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0071900 GO:0046944 biolink:BiologicalProcess protein carbamoylation The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2. go-plus.json protein amino acid carbamoylation http://purl.obolibrary.org/obo/GO_0046944 GO:0032335 biolink:BiologicalProcess regulation of activin secretion Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell. go-plus.json http://purl.obolibrary.org/obo/GO_0032335 GO:0032334 biolink:BiologicalProcess inhibin secretion The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0032334 GO:0032333 biolink:BiologicalProcess activin secretion The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone. go-plus.json http://purl.obolibrary.org/obo/GO_0032333 GO:0032332 biolink:BiologicalProcess positive regulation of chondrocyte differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. go-plus.json upregulation of chondrocyte differentiation|up regulation of chondrocyte differentiation|activation of chondrocyte differentiation|stimulation of chondrocyte differentiation|up-regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0032332 GO:0032331 biolink:BiologicalProcess negative regulation of chondrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. go-plus.json down regulation of chondrocyte differentiation|downregulation of chondrocyte differentiation|down-regulation of chondrocyte differentiation|inhibition of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0032331 GO:0032330 biolink:BiologicalProcess regulation of chondrocyte differentiation Any process that modulates the frequency, rate or extent of chondrocyte differentiation. go-plus.json http://purl.obolibrary.org/obo/GO_0032330 GO:0032329 biolink:BiologicalProcess serine transport The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json serine import http://purl.obolibrary.org/obo/GO_0032329 GO:0032328 biolink:BiologicalProcess alanine transport The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json http://purl.obolibrary.org/obo/GO_0032328 GO:0032327 biolink:BiologicalProcess W-molybdopterin cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands. go-plus.json W-molybdopterin cofactor catabolism|W-molybdopterin cofactor degradation|Moco catabolic process|W-molybdopterin cofactor breakdown|Moco catabolism http://purl.obolibrary.org/obo/GO_0032327 GO:0032326 biolink:BiologicalProcess Mo-molybdopterin cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. go-plus.json Mo-molybdopterin cofactor breakdown|Moco catabolic process|Mo-molybdopterin cofactor catabolism|Mo-molybdopterin cofactor degradation|Moco catabolism http://purl.obolibrary.org/obo/GO_0032326 GO:0032325 biolink:BiologicalProcess molybdopterin cofactor catabolic process The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. go-plus.json http://purl.obolibrary.org/obo/GO_0032325 GO:0046954 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046954 CHEBI:84539 biolink:ChemicalSubstance 2-demethylmenaquinol-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84539 chebi_ph7_3 GO:0007389 biolink:BiologicalProcess pattern specification process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. go-plus.json pattern formation|pattern biosynthesis http://purl.obolibrary.org/obo/GO_0007389 goslim_drosophila GO:0046953 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046953 GO:0046952 biolink:BiologicalProcess ketone body catabolic process The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA. MetaCyc:PWY66-368|Reactome:R-HSA-77108 go-plus.json utilization of ketone bodies|ketolysis|ketone body degradation|ketone body breakdown|ketone body catabolism http://purl.obolibrary.org/obo/GO_0046952 CHEBI:142862 biolink:ChemicalSubstance andrastin B go-plus.json http://purl.obolibrary.org/obo/CHEBI_142862 GO:0007388 biolink:BiologicalProcess posterior compartment specification The process involved in the specification of cell identity in the posterior compartments of the segmented embryo. go-plus.json http://purl.obolibrary.org/obo/GO_0007388 CHEBI:84537 biolink:ChemicalSubstance dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_84537 chebi_ph7_3 GO:0046951 biolink:BiologicalProcess ketone body biosynthetic process The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA. go-plus.json ketone body anabolism|ketone body synthesis|ketone body formation|ketone body biosynthesis http://purl.obolibrary.org/obo/GO_0046951 GO:0007387 biolink:BiologicalProcess anterior compartment pattern formation The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo. go-plus.json anterior compartment pattern specification http://purl.obolibrary.org/obo/GO_0007387 CHEBI:84536 biolink:ChemicalSubstance menaquinol-6 go-plus.json http://purl.obolibrary.org/obo/CHEBI_84536 chebi_ph7_3 GO:0007386 biolink:BiologicalProcess compartment pattern specification The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation. go-plus.json compartment specification http://purl.obolibrary.org/obo/GO_0007386 GO:0046950 biolink:BiologicalProcess cellular ketone body metabolic process The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism. go-plus.json cellular ketone body metabolism http://purl.obolibrary.org/obo/GO_0046950 goslim_pir GO:0007385 biolink:BiologicalProcess specification of segmental identity, abdomen The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0007385 GO:0007384 biolink:BiologicalProcess specification of segmental identity, thorax The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0007384 GO:0007383 biolink:BiologicalProcess specification of segmental identity, antennal segment The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. go-plus.json http://purl.obolibrary.org/obo/GO_0007383 GO:0007393 biolink:BiologicalProcess dorsal closure, leading edge cell fate determination The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed. go-plus.json http://purl.obolibrary.org/obo/GO_0007393 CHEBI:84531 biolink:ChemicalSubstance 2-methoxy-3-methyl-6-all-trans-nonaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84531 chebi_ph7_3 CHEBI:60575 biolink:ChemicalSubstance phenoxy herbicide go-plus.json http://purl.obolibrary.org/obo/CHEBI_60575 GO:0007392 biolink:BiologicalProcess initiation of dorsal closure Events that occur at the start of dorsal closure. go-plus.json http://purl.obolibrary.org/obo/GO_0007392 CHEBI:84530 biolink:ChemicalSubstance 6-methoxy-3-methyl-2-all-trans-heptaprenylhydroquinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_84530 chebi_ph7_3 GO:0007391 biolink:BiologicalProcess dorsal closure The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally. go-plus.json http://purl.obolibrary.org/obo/GO_0007391 CHEBI:59595 biolink:ChemicalSubstance arabinofuranosyl group go-plus.json http://purl.obolibrary.org/obo/CHEBI_59595 GO:0046959 biolink:BiologicalProcess habituation A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented. Wikipedia:Habituation go-plus.json http://purl.obolibrary.org/obo/GO_0046959 GO:0007390 biolink:BiologicalProcess germ-band shortening The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo. go-plus.json germ-band retraction http://purl.obolibrary.org/obo/GO_0007390 GO:0046958 biolink:BiologicalProcess nonassociative learning A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment. go-plus.json unconditional response http://purl.obolibrary.org/obo/GO_0046958 CHEBI:60579 biolink:ChemicalSubstance calcium oxalate go-plus.json http://purl.obolibrary.org/obo/CHEBI_60579 GO:0046957 biolink:BiologicalProcess negative phototaxis The directed movement of a cell or organism away from a source of light. go-plus.json negative phototactic behavior|negative taxis in response to light|negative phototactic behaviour http://purl.obolibrary.org/obo/GO_0046957 CHEBI:142867 biolink:ChemicalSubstance andrastin C go-plus.json http://purl.obolibrary.org/obo/CHEBI_142867 GO:0046956 biolink:BiologicalProcess positive phototaxis The directed movement of a cell or organism towards a source of light. go-plus.json positive phototactic behavior|positive taxis in response to light|positive phototactic behaviour http://purl.obolibrary.org/obo/GO_0046956 GO:0046955 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0046955 GO:0032324 biolink:BiologicalProcess molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. MetaCyc:Molybdenum-Cofactor-Biosynthesis go-plus.json molybdopterin cofactor biosynthesis|molybdopterin cofactor anabolism|molybdopterin cofactor synthesis|molybdopterin cofactor formation http://purl.obolibrary.org/obo/GO_0032324 GO:0032323 biolink:BiologicalProcess lipoate catabolic process The chemical reactions and pathways resulting in the breakdown of lipoate. go-plus.json lipoic acid degradation|lipoic acid breakdown|lipoic acid catabolism http://purl.obolibrary.org/obo/GO_0032323 GO:0032322 biolink:BiologicalProcess ubiquinone catabolic process The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme. go-plus.json ubiquinone catabolism|ubiquinone degradation|ubiquinone breakdown http://purl.obolibrary.org/obo/GO_0032322 GO:0032321 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032321 GO:0032320 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0032320 UBERON:0002195 biolink:AnatomicalEntity trabecula of lymph node Membranous process coming from capsule of lymph node[WP]. go-plus.json lymph node trabecula|lymph node trabeculum http://purl.obolibrary.org/obo/UBERON_0002195 UBERON:0002194 biolink:AnatomicalEntity capsule of lymph node Capsule surrounding lymph node composed of connective tissue with some plain muscle fibers. go-plus.json capsula nodi lymphoidei|lymph node capsule http://purl.obolibrary.org/obo/UBERON_0002194 UBERON:0002196 biolink:AnatomicalEntity adenohypophysis The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates several physiological processes including stress, growth, and reproduction[WP]. The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin[ZFA]. go-plus.json anterior lobe of pituitary gland|AHP|anterior pituitary|anterior lobe of the pituitary|lobus anterior (glandula pituitaria)|lobus anterior|pituitary glandanterior lobe|anterior hypophysis|lobus anterior hypophysis|pituitary anterior lobe|anterior lobe of pituitary|cranial lobe|anterior pituitary gland|anterior lobe (hypophysis)|pituitary gland, anterior lobe|anterior lobe of hypophysis|rostral lobe http://purl.obolibrary.org/obo/UBERON_0002196 UBERON:0002191 biolink:AnatomicalEntity subiculum Part of the hippocampal formation that is bounded by the entorhinal cortex and area CA1. It is characterized on the CA1 border by an abrupt widening of the pyramidal cell layer. A molecular layer is present that is continuous with that of CA1, although the stratum radiatum is no longer present. The stratum oriens is also not present. adapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 468) go-plus.json gyrus parahippocampalis|subiculum cornu ammonis|subiculum hippocampi|subicular cortex http://purl.obolibrary.org/obo/UBERON_0002191 UBERON:0002190 biolink:AnatomicalEntity subcutaneous adipose tissue A portion of adipose tissue that is part of the hypodermis, beneath the dermis. go-plus.json panniculus adiposus (tela subcutanea)|fatty layer of subcutaneous tissue|subcutaneous fat|fatty layer of superficial fascia|panniculus adiposus telae subcutaneae|panniculus adiposus|subcutaneous fat layer|hypodermis fat layer http://purl.obolibrary.org/obo/UBERON_0002190 UBERON:0002193 biolink:AnatomicalEntity hemolymphoid system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. go-plus.json hematolymphoid system|lymphomyeloid complex|haemolymphoid system http://purl.obolibrary.org/obo/UBERON_0002193 UBERON:0002199 biolink:AnatomicalEntity integument The dermis, epidermis and hypodermis. go-plus.json dermoid system|integumentum commune|skin|skin plus hypodermis|tegument|dermis plus epidermis plus hypodermis|the integument|vertebrate integument|dermal system|skin and subcutaneous tissue http://purl.obolibrary.org/obo/UBERON_0002199 UBERON:0002198 biolink:AnatomicalEntity neurohypophysis The posterior part of the pituitary gland that secretes hormones involved in blood pressure regulation such as oxytocin and antidiuretic hormon. go-plus.json lobus nervosus|infundibular process|pituitary gland, neural lobe|lobus posterior|posterior lobe of hypophysis|pituitary gland neural lobe|lobus posterior (glandula pituitaria)|posterior lobe of pituitary|neural lobe of pituitary|neuro hypophysis|pituitary gland, posterior lobe|lobus posterior hypophysis|posterior pituitary gland|NHP|lobus nervosus neurohypophysis|neural lobe|neurohypophysis|posterior lobe of pituitary gland|neural lobe of pituitary gland|posterior pituitary http://purl.obolibrary.org/obo/UBERON_0002198 PATO:0000947 biolink:OntologyClass elliptic A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section. go-plus.json ellipsoid|ovoid|ellipse-shaped|oval|elliptical http://purl.obolibrary.org/obo/PATO_0000947 GO:0140007 biolink:CellularComponent KICSTOR complex A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2. go-plus.json http://purl.obolibrary.org/obo/GO_0140007 GO:0140009 biolink:BiologicalProcess L-aspartate import across plasma membrane The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol. go-plus.json http://purl.obolibrary.org/obo/GO_0140009 UBERON:0002184 biolink:AnatomicalEntity segmental bronchus The tertiary bronchi (also known as the segmental bronchi) arise from the secondary bronchi. The respiratory epithelium lining their lumen is surrounded by a layer of smooth muscle. This layer is composed of two ribbons of smooth muscle that spiral in opposite directions. The smooth muscle layer is surrounded by irregular plates of hyaline cartilage which help maintain the patency of the airway. Each of the tertiary bronchi serves a specific bronchopulmonary segment. There are 10 tertiary bronchi in the right lung, and eight in the left. The tertiary bronchi get smaller and divide into primary bronchioles. [WP,unvetted]. go-plus.json tertiary bronchus http://purl.obolibrary.org/obo/UBERON_0002184 UBERON:0002183 biolink:AnatomicalEntity lobar bronchus The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi[GO]. go-plus.json bronchi lobaris|secondary bronchi|lobar bronchi|secondary bronchus http://purl.obolibrary.org/obo/UBERON_0002183 UBERON:0002186 biolink:AnatomicalEntity bronchiole the conducting airway of the lungs found terminal to the bronchi; these structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching go-plus.json lobular bronchiole|bronchiolus|bronchioli http://purl.obolibrary.org/obo/UBERON_0002186 UBERON:0002185 biolink:AnatomicalEntity bronchus the upper conducting airways of the lung; these airways arise from the terminus of the trachea go-plus.json bronchial tissue|bronchi|bronchial trunk http://purl.obolibrary.org/obo/UBERON_0002185 CHEBI:11502 biolink:ChemicalSubstance 2-acylglycerophosphocholine go-plus.json http://purl.obolibrary.org/obo/CHEBI_11502 UBERON:0002187 biolink:AnatomicalEntity terminal bronchiole the last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls go-plus.json bronchioli terminalis|terminal bronchiole tube|bronchiolus terminalis http://purl.obolibrary.org/obo/UBERON_0002187 NCBITaxon:32351 biolink:OrganismalEntity melanogaster subgroup go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_32351 GO:0032294 biolink:BiologicalProcess peripheral nervous system non-myelinated axon ensheathment The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons. go-plus.json ensheathment of non-myelinated axons in peripheral nervous system http://purl.obolibrary.org/obo/GO_0032294 GO:0032293 biolink:BiologicalProcess non-myelinated axon ensheathment in central nervous system The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system. go-plus.json ensheathment of non-myelinated axons in central nervous system http://purl.obolibrary.org/obo/GO_0032293 GO:0032292 biolink:BiologicalProcess peripheral nervous system axon ensheathment The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. go-plus.json ensheathment of axons in peripheral nervous system http://purl.obolibrary.org/obo/GO_0032292 GO:0032291 biolink:BiologicalProcess axon ensheathment in central nervous system The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. go-plus.json ensheathment of axons in central nervous system http://purl.obolibrary.org/obo/GO_0032291 GO:0032290 biolink:BiologicalProcess peripheral nervous system myelin formation The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. go-plus.json myelin formation in peripheral nervous system http://purl.obolibrary.org/obo/GO_0032290 NCBITaxon:32346 biolink:OrganismalEntity melanogaster group go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_32346 GO:0032299 biolink:CellularComponent ribonuclease H2 complex A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p. go-plus.json RNase H2 complex http://purl.obolibrary.org/obo/GO_0032299 GO:0032298 biolink:BiologicalProcess positive regulation of DNA-dependent DNA replication initiation Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication. go-plus.json stimulation of DNA replication initiation|activation of DNA replication initiation|up-regulation of DNA replication initiation|negative regulation of DNA replication initiation|up regulation of DNA replication initiation|upregulation of DNA replication initiation http://purl.obolibrary.org/obo/GO_0032298 GO:0032297 biolink:BiologicalProcess negative regulation of DNA-dependent DNA replication initiation Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication. go-plus.json negative regulation of DNA replication initiation|down-regulation of DNA replication initiation|downregulation of DNA replication initiation|down regulation of DNA replication initiation|inhibition of DNA replication initiation http://purl.obolibrary.org/obo/GO_0032297 NCBITaxon:32341 biolink:OrganismalEntity Sophophora go-plus.json http://purl.obolibrary.org/obo/NCBITaxon_32341 GO:0032296 biolink:MolecularActivity double-stranded RNA-specific ribonuclease activity Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules. go-plus.json double-stranded RNA-specific RNase activity|dsRNA-specific ribonuclease activity|dsRNA-specific RNase activity http://purl.obolibrary.org/obo/GO_0032296 GO:0032295 biolink:BiologicalProcess ensheathment of neuronal cell bodies The process in which satellite glial cells isolate neuronal cell bodies. go-plus.json http://purl.obolibrary.org/obo/GO_0032295 GO:0032283 biolink:CellularComponent plastid acetate CoA-transferase complex An acetate CoA-transferase complex located in the stroma of a plastid. go-plus.json http://purl.obolibrary.org/obo/GO_0032283 GO:0032282 biolink:CellularComponent plastid acetyl-CoA carboxylase complex An acetyl-CoA carboxylase complex located in the stroma of a plastid. go-plus.json plastid ACCase complex http://purl.obolibrary.org/obo/GO_0032282 GO:0032281 biolink:CellularComponent AMPA glutamate receptor complex An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. go-plus.json alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|AMPA-selective glutamate receptor complex|AMPA receptor http://purl.obolibrary.org/obo/GO_0032281 GO:0032280 biolink:CellularComponent symmetric synapse A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory. go-plus.json Gray's type II synapse http://purl.obolibrary.org/obo/GO_0032280 GO:0032289 biolink:BiologicalProcess central nervous system myelin formation The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. go-plus.json myelin formation in central nervous system http://purl.obolibrary.org/obo/GO_0032289 GO:0032288 biolink:BiologicalProcess myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. go-plus.json myelin formation http://purl.obolibrary.org/obo/GO_0032288 GO:0032287 biolink:BiologicalProcess peripheral nervous system myelin maintenance The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state. go-plus.json myelin maintenance in peripheral nervous system http://purl.obolibrary.org/obo/GO_0032287 GO:0032286 biolink:BiologicalProcess central nervous system myelin maintenance The process in which the structure and material content of mature central nervous system myelin is kept in a functional state. go-plus.json myelin maintenance in central nervous system http://purl.obolibrary.org/obo/GO_0032286 GO:0032285 biolink:BiologicalProcess non-myelinated axon ensheathment The process in which a non-myelinating glial cell membrane closes around an axon. go-plus.json ensheathment of non-myelinated axons http://purl.obolibrary.org/obo/GO_0032285 GO:0032284 biolink:CellularComponent plastid biotin carboxylase complex A biotin carboxylase complex located in the stroma of a plastid. go-plus.json http://purl.obolibrary.org/obo/GO_0032284 GO:0071880 biolink:BiologicalProcess adenylate cyclase-activating adrenergic receptor signaling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). go-plus.json activation of adenylate cyclase activity by adrenergic receptor signaling pathway|adrenergic receptor, adenylate cyclase activating pathway|adrenergic receptor, adenylyl cyclase activating pathway|activation of adenylate cyclase activity by adrenergic receptor signalling pathway http://purl.obolibrary.org/obo/GO_0071880 GO:1900759 biolink:BiologicalProcess positive regulation of D-amino-acid oxidase activity Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity. go-plus.json up-regulation of new yellow enzyme|activation of D-amino-acid:oxygen oxidoreductase (deaminating)|up regulation of L-amino acid:O2 oxidoreductase activity|positive regulation of L-amino acid:O2 oxidoreductase activity|upregulation of D-amino-acid oxidase activity|positive regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|activation of L-amino acid:O2 oxidoreductase activity|up regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|upregulation of new yellow enzyme|up-regulation of L-amino acid:O2 oxidoreductase activity|up regulation of D-amino-acid oxidase activity|activation of D-amino-acid oxidase activity|upregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up regulation of new yellow enzyme|positive regulation of new yellow enzyme|upregulation of L-amino acid:O2 oxidoreductase activity|activation of new yellow enzyme|up-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up-regulation of D-amino-acid oxidase activity http://purl.obolibrary.org/obo/GO_1900759 GO:1900756 biolink:BiologicalProcess protein processing in phagocytic vesicle Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation. go-plus.json peptidolysis during protein maturation in phagocytic vesicle|peptidolysis during protein maturation in phagosome|protein processing in phagosome|protein maturation by peptide bond hydrolysis in phagosome|protein maturation by peptide bond cleavage in phagocytic vesicle|protein maturation by proteolysis in phagocytic vesicle|protein maturation by peptide bond cleavage in phagosome|protein maturation by peptide bond hydrolysis in phagocytic vesicle|protein maturation by proteolysis in phagosome http://purl.obolibrary.org/obo/GO_1900756 UBERON:0002119 biolink:AnatomicalEntity left ovary An ovary that is part of a left side of organism [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002119 GO:1900755 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_1900755 UBERON:0002118 biolink:AnatomicalEntity right ovary An ovary that is part of a right side of organism [Automatically generated definition]. go-plus.json http://purl.obolibrary.org/obo/UBERON_0002118 GO:1900758 biolink:BiologicalProcess negative regulation of D-amino-acid oxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity. go-plus.json negative regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|inhibition of new yellow enzyme|negative regulation of L-amino acid:O2 oxidoreductase activity|down-regulation of L-amino acid:O2 oxidoreductase activity|down regulation of D-amino-acid oxidase activity|downregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down regulation of new yellow enzyme|downregulation of D-amino-acid oxidase activity|down regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|downregulation of new yellow enzyme|inhibition of L-amino acid:O2 oxidoreductase activity|down-regulation of D-amino-acid oxidase activity|inhibition of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of new yellow enzyme|negative regulation of new yellow enzyme|down regulation of L-amino acid:O2 oxidoreductase activity|inhibition of D-amino-acid oxidase activity|downregulation of L-amino acid:O2 oxidoreductase activity http://purl.obolibrary.org/obo/GO_1900758 GO:1900757 biolink:BiologicalProcess regulation of D-amino-acid oxidase activity Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity. go-plus.json regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|regulation of new yellow enzyme|regulation of L-amino acid:O2 oxidoreductase activity http://purl.obolibrary.org/obo/GO_1900757 GO:1900752 biolink:BiologicalProcess malonic acid transport The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json HOOC-CH2-COOH transport|propanedioic acid transport|H2malo transport|C3H4O4 transport http://purl.obolibrary.org/obo/GO_1900752 GO:1900751 biolink:BiologicalProcess 4-(trimethylammonio)butanoate transport The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json butyrobetaine transport|gamma-butyrobetaine transport|C7H15NO2 transport|gamma-Butyrobetain transport|deoxycarnitine transport|Actinine transport|4-butyrobetaine transport|4-(N-trimethylamino)butyrate transport http://purl.obolibrary.org/obo/GO_1900751 GO:1900754 biolink:BiologicalProcess 4-hydroxyphenylacetate transport The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json 4-hydroxybenzeneacetate transport|2-(4-hydroxyphenyl)ethanoate transport|(4-hydroxyphenyl)acetate transport|(p-hydroxyphenyl)acetate transport http://purl.obolibrary.org/obo/GO_1900754 GO:1900753 biolink:BiologicalProcess doxorubicin transport The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. go-plus.json 14-hydroxydaunorubicine transport|Adriamycin transport|(8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione transport|doxorubicinum transport|(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|14-hydroxydaunomycin transport|doxorubicine transport http://purl.obolibrary.org/obo/GO_1900753 GO:1900750 biolink:MolecularActivity oligopeptide binding Binding to an oligopeptide. go-plus.json oligopeptides binding|Oligopeptid binding|oligopeptido binding http://purl.obolibrary.org/obo/GO_1900750 GO:0140062 biolink:MolecularActivity 5-formylcytosine dioxygenase activity Catalysis of the reaction: 5-formylcytosine+ 2-oxoglutarate + O2 = 5-carboxylcytosine + succinate + CO2. go-plus.json 5fC dioxygenase http://purl.obolibrary.org/obo/GO_0140062 CHEBI:35530 biolink:ChemicalSubstance beta-adrenergic antagonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_35530 CHEBI:11563 biolink:ChemicalSubstance 2-deoxy-alpha-D-ribose 1-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11563 GO:0140065 biolink:MolecularActivity peptide butyryltransferase activity Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide. go-plus.json protein butyryltransferase activity http://purl.obolibrary.org/obo/GO_0140065 UBERON:0002120 biolink:AnatomicalEntity pronephros In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. go-plus.json pronephron|pronephric kidney|archinephron|embryonic kidney http://purl.obolibrary.org/obo/UBERON_0002120 GO:0140064 biolink:MolecularActivity peptide crotonyltransferase activity Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide. go-plus.json protein crotonyltransferase activity http://purl.obolibrary.org/obo/GO_0140064 CHEBI:11561 biolink:ChemicalSubstance 2-dehydropantoate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11561 chebi_ph7_3 GO:0140067 biolink:BiologicalProcess peptidyl-lysine butyrylation The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid. go-plus.json http://purl.obolibrary.org/obo/GO_0140067 CHEBI:3789 biolink:ChemicalSubstance cobalt-precorrin-6B go-plus.json http://purl.obolibrary.org/obo/CHEBI_3789 GO:0140066 biolink:BiologicalProcess peptidyl-lysine crotonylation The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid. go-plus.json http://purl.obolibrary.org/obo/GO_0140066 GO:0140069 biolink:MolecularActivity histone butyryltransferase activity Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone. go-plus.json http://purl.obolibrary.org/obo/GO_0140069 GO:0140068 biolink:MolecularActivity histone crotonyltransferase activity Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone. go-plus.json http://purl.obolibrary.org/obo/GO_0140068 GO:0071889 biolink:MolecularActivity 14-3-3 protein binding Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins. go-plus.json http://purl.obolibrary.org/obo/GO_0071889 GO:0071888 biolink:BiologicalProcess macrophage apoptotic process Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues. go-plus.json activation-induced cell death|AICD|macrophage apoptosis http://purl.obolibrary.org/obo/GO_0071888 UBERON:0002126 biolink:AnatomicalEntity solitary tract nuclear complex The solitary tract and nucleus are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves. [WP,unvetted]. go-plus.json nucleus tractus solitarii|solitary nuclei|nuclei of solitary tract http://purl.obolibrary.org/obo/UBERON_0002126 CHEBI:59505 biolink:ChemicalSubstance 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate(2-) go-plus.json http://purl.obolibrary.org/obo/CHEBI_59505 chebi_ph7_3 GO:0071887 biolink:BiologicalProcess leukocyte apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. go-plus.json leukocyte apoptosis http://purl.obolibrary.org/obo/GO_0071887 UBERON:0002125 biolink:AnatomicalEntity thymus lobule A lobule that is part of a thymus. Divided into an outer cortex and inner medulla and separated from each other by connective tissue septa, but with the medullary tissue continuous from lobule to lobule.[ncit,modified]. go-plus.json thymic lobule|thymus lobule|lobule of thymus http://purl.obolibrary.org/obo/UBERON_0002125 UBERON:0002128 biolink:AnatomicalEntity superior olivary complex A a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. go-plus.json superior olivary nucleus|regio olivaris superioris|superior olive|superior olivary nucleus (Barr & Kiernan)|superior olivary nuclei|nucleus olivaris superior http://purl.obolibrary.org/obo/UBERON_0002128 GO:0071886 biolink:MolecularActivity 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding Binding to the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug. go-plus.json 4-iodo-2,5-dimethoxyphenylisopropylamine binding|1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane binding|(+/-)2-(4-iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine binding http://purl.obolibrary.org/obo/GO_0071886 UBERON:0002127 biolink:AnatomicalEntity inferior olivary complex largest nucleus situated in the olivary body, part of the medulla oblongata. It is closely associated with the cerebellum, but its specific function is voluntary body movements. go-plus.json caudal olivary nuclei|inferior olive|oliva|inferior olivary nuclei|inferior olivary nuclear complex|nuclei olivares inferiores|inferior olivary complex (Vieussens)|regio olivaris inferior|nuclei olivares caudales|nucleus olivaris caudalis|inferior olivary nucleus|nucleus olivaris inferior|complexus olivaris inferior|complexus olivaris inferior; nuclei olivares inferiores http://purl.obolibrary.org/obo/UBERON_0002127 GO:0071885 biolink:MolecularActivity N-terminal protein N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser. go-plus.json X-Pro-Lys N-terminal methyltransferase http://purl.obolibrary.org/obo/GO_0071885 UBERON:0002122 biolink:AnatomicalEntity capsule of thymus The fibrous connective tissue surrounding the thymus. go-plus.json thymus capsule|thymic capsule http://purl.obolibrary.org/obo/UBERON_0002122 GO:0071884 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0071884 GO:0071883 biolink:BiologicalProcess MAPK-activating adrenergic receptor signaling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade. go-plus.json activation of MAPK activity by adrenergic receptor signaling pathway|activation of MAP kinase activity by adrenergic receptor signalling pathway|activation of MAPK activity by adrenergic receptor signalling pathway|activation of MAP kinase activity by adrenergic receptor signaling pathway http://purl.obolibrary.org/obo/GO_0071883 UBERON:0002124 biolink:AnatomicalEntity medulla of thymus Medullary portion of thymus. The reticulum is coarser than in the cortex, the lymphoid cells are relatively fewer in number, and there are found peculiar nest-like bodies, the concentric corpuscles of Hassall. These concentric corpuscles are composed of a central mass, consisting of one or more granular cells, and of a capsule formed of epithelioid cells. They are the remains of the epithelial tubes, which grow out from the third branchial pouches of the embryo to form the thymus. Each follicle is surrounded by a vascular plexus, from which vessels pass into the interior, and radiate from the periphery toward the center, forming a second zone just within the margin of the medullary portion. In the center of the medullary portion there are very few vessels, and they are of minute size. go-plus.json medulla of thymus gland|thymus gland medulla|thymus medulla http://purl.obolibrary.org/obo/UBERON_0002124 GO:0071882 biolink:BiologicalProcess phospholipase C-activating adrenergic receptor signaling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). go-plus.json adrenergic receptor, phospholipase C activating pathway|activation of phospholipase C activity by adrenergic receptor signalling pathway|activation of phospholipase C activity by adrenergic receptor signaling pathway http://purl.obolibrary.org/obo/GO_0071882 GO:0140061 biolink:MolecularActivity 5-hydroxymethylcytosine dioxygenase activity Catalysis of the reaction: 5-hydroxymethylcytosine + 2-oxoglutarate + O2 = 5-formylcytosine + succinate + CO2. go-plus.json 5hmC dioxygenase http://purl.obolibrary.org/obo/GO_0140061 UBERON:0002123 biolink:AnatomicalEntity cortex of thymus the outer part of a thymus lobule that surrounds the medulla and is composed of closely packed lymphocytes go-plus.json thymus cortex|thymic cortex http://purl.obolibrary.org/obo/UBERON_0002123 GO:0071881 biolink:BiologicalProcess adenylate cyclase-inhibiting adrenergic receptor signaling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). go-plus.json adrenergic receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway|inhibition of adenylate cyclase activity by adrenergic receptor signalling pathway|adrenergic receptor, adenylate cyclase inhibiting pathway http://purl.obolibrary.org/obo/GO_0071881 GO:0140060 biolink:BiologicalProcess axon arborization The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches. go-plus.json http://purl.obolibrary.org/obo/GO_0140060 GO:1900767 biolink:BiologicalProcess fonsecin metabolic process The chemical reactions and pathways involving fonsecin. go-plus.json fonsecin metabolism http://purl.obolibrary.org/obo/GO_1900767 UBERON:0002108 biolink:AnatomicalEntity small intestine Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]. go-plus.json intestinum tenue|anterior intestine|small bowel|small intestine|mid intestine http://purl.obolibrary.org/obo/UBERON_0002108 GO:1900766 biolink:BiologicalProcess emericellin biosynthetic process The chemical reactions and pathways resulting in the formation of emericellin. go-plus.json emericellin synthesis|Variecoxanthone B synthesis|emericellin formation|Variecoxanthone B formation|Variecoxanthone B biosynthesis|Variecoxanthone B biosynthetic process|emericellin anabolism|Variecoxanthone B anabolism|emericellin biosynthesis http://purl.obolibrary.org/obo/GO_1900766 UBERON:0002107 biolink:AnatomicalEntity liver An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. go-plus.json jecur|iecur http://purl.obolibrary.org/obo/UBERON_0002107 GO:1900769 biolink:BiologicalProcess fonsecin biosynthetic process The chemical reactions and pathways resulting in the formation of fonsecin. go-plus.json fonsecin anabolism|fonsecin synthesis|fonsecin formation|fonsecin biosynthesis http://purl.obolibrary.org/obo/GO_1900769 UBERON:0002109 biolink:AnatomicalEntity pair of nares Pair of nostrils. go-plus.json nostrils|set of nares|nares set|nares|pair of nostrils http://purl.obolibrary.org/obo/UBERON_0002109 GO:1900768 biolink:BiologicalProcess fonsecin catabolic process The chemical reactions and pathways resulting in the breakdown of fonsecin. go-plus.json fonsecin catabolism|fonsecin degradation|fonsecin breakdown http://purl.obolibrary.org/obo/GO_1900768 GO:1900763 biolink:BiologicalProcess averantin biosynthetic process The chemical reactions and pathways resulting in the formation of averantin. go-plus.json averantin biosynthesis|averantin anabolism|averantin synthesis|averantin formation http://purl.obolibrary.org/obo/GO_1900763 GO:1900762 biolink:BiologicalProcess averantin catabolic process The chemical reactions and pathways resulting in the breakdown of averantin. go-plus.json averantin breakdown|averantin catabolism|averantin degradation http://purl.obolibrary.org/obo/GO_1900762 GO:0140059 biolink:BiologicalProcess dendrite arborization The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches. go-plus.json http://purl.obolibrary.org/obo/GO_0140059 GO:1900765 biolink:BiologicalProcess emericellin catabolic process The chemical reactions and pathways resulting in the breakdown of emericellin. go-plus.json Variecoxanthone B catabolism|emericellin degradation|Variecoxanthone B degradation|emericellin breakdown|Variecoxanthone B breakdown|Variecoxanthone B catabolic process|emericellin catabolism http://purl.obolibrary.org/obo/GO_1900765 GO:1900764 biolink:BiologicalProcess emericellin metabolic process The chemical reactions and pathways involving emericellin. go-plus.json emericellin metabolism|Variecoxanthone B metabolism|Variecoxanthone B metabolic process http://purl.obolibrary.org/obo/GO_1900764 GO:1900761 biolink:BiologicalProcess averantin metabolic process The chemical reactions and pathways involving averantin. go-plus.json averantin metabolism http://purl.obolibrary.org/obo/GO_1900761 GO:1900760 biolink:BiologicalProcess negative regulation of sterigmatocystin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process. go-plus.json down-regulation of sterigmatocystin anabolism|negative regulation of sterigmatocystin anabolism|inhibition of sterigmatocystin biosynthesis|down-regulation of sterigmatocystin synthesis|negative regulation of sterigmatocystin synthesis|negative regulation of sterigmatocystin formation|down-regulation of sterigmatocystin formation|down regulation of sterigmatocystin biosynthesis|downregulation of sterigmatocystin anabolism|down regulation of sterigmatocystin biosynthetic process|downregulation of sterigmatocystin biosynthesis|down regulation of sterigmatocystin anabolism|downregulation of sterigmatocystin biosynthetic process|downregulation of sterigmatocystin synthesis|downregulation of sterigmatocystin formation|down regulation of sterigmatocystin synthesis|down regulation of sterigmatocystin formation|inhibition of sterigmatocystin anabolism|down-regulation of sterigmatocystin biosynthesis|negative regulation of sterigmatocystin biosynthesis|down-regulation of sterigmatocystin biosynthetic process|inhibition of sterigmatocystin synthesis|inhibition of sterigmatocystin formation|inhibition of sterigmatocystin biosynthetic process http://purl.obolibrary.org/obo/GO_1900760 GO:0140052 biolink:BiologicalProcess cellular response to oxidised low-density lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus. go-plus.json cellular response to oxidised LDL particle stimulus|cellular response to oxLDL particle stimulus|cellular response to ox-LDL particle stimulus|cellular response to oxidized low-density lipoprotein particle stimulus|cellular response to oxidized LDL particle stimulus http://purl.obolibrary.org/obo/GO_0140052 GO:0140051 biolink:BiologicalProcess positive regulation of endocardial cushion to mesenchymal transition Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition. go-plus.json http://purl.obolibrary.org/obo/GO_0140051 CHEBI:3795 biolink:ChemicalSubstance cobalt-precorrin-8 go-plus.json http://purl.obolibrary.org/obo/CHEBI_3795 CHEBI:35544 biolink:ChemicalSubstance EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor go-plus.json http://purl.obolibrary.org/obo/CHEBI_35544 GO:0140053 biolink:BiologicalProcess mitochondrial gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. go-plus.json http://purl.obolibrary.org/obo/GO_0140053 goslim_pombe GO:0140056 biolink:BiologicalProcess organelle localization by membrane tethering The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. go-plus.json http://purl.obolibrary.org/obo/GO_0140056 goslim_pombe CHEBI:35545 biolink:ChemicalSubstance bipyridine go-plus.json http://purl.obolibrary.org/obo/CHEBI_35545 GO:0140058 biolink:BiologicalProcess neuron projection arborization The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites. go-plus.json branching morphogenesis of a neurite|neurite branching|branching morphogenesis of a neuron projection|neuron projection branching|neurite arborization http://purl.obolibrary.org/obo/GO_0140058 GO:0071879 biolink:BiologicalProcess positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. go-plus.json positive regulation of adrenergic receptor signaling pathway|positive regulation of adrenergic receptor signalling pathway http://purl.obolibrary.org/obo/GO_0071879 GO:0071878 biolink:BiologicalProcess negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. go-plus.json negative regulation of adrenergic receptor signaling pathway|negative regulation of adrenergic receptor signalling pathway http://purl.obolibrary.org/obo/GO_0071878 GO:0140057 biolink:BiologicalProcess vacuole-mitochondria membrane tethering The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. go-plus.json http://purl.obolibrary.org/obo/GO_0140057 GO:0071877 biolink:BiologicalProcess regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. go-plus.json regulation of adrenergic receptor signalling pathway|regulation of adrenergic receptor signaling pathway http://purl.obolibrary.org/obo/GO_0071877 GO:0071876 biolink:BiologicalProcess obsolete initiation of adrenergic receptor signal transduction OBSOLETE. A process of signal initiation in which epinephrine or norepinephrine causes activation of an adrenergic receptor. go-plus.json initiation of adrenergic receptor signal transduction http://purl.obolibrary.org/obo/GO_0071876 UBERON:0002114 biolink:AnatomicalEntity duodenum The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one). go-plus.json upper intestine|proximal intestine http://purl.obolibrary.org/obo/UBERON_0002114 GO:0071875 biolink:BiologicalProcess adrenergic receptor signaling pathway A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. go-plus.json adrenergic receptor signalling pathway|adrenoceptor signaling pathway http://purl.obolibrary.org/obo/GO_0071875 CHEBI:3790 biolink:ChemicalSubstance cobalt-precorrin-2 go-plus.json http://purl.obolibrary.org/obo/CHEBI_3790 GO:0022900 biolink:BiologicalProcess electron transport chain A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors. Wikipedia:Electron_transport_chain go-plus.json http://purl.obolibrary.org/obo/GO_0022900 goslim_pir GO:0071874 biolink:BiologicalProcess cellular response to norepinephrine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. go-plus.json cellular response to noradrenaline stimulus http://purl.obolibrary.org/obo/GO_0071874 UBERON:0002111 biolink:AnatomicalEntity artery smooth muscle tissue A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]. go-plus.json artery smooth muscle|arterial smooth muscle|artery smooth muscle tissue|arterial smooth muscle cell|smooth muscle of artery http://purl.obolibrary.org/obo/UBERON_0002111 GO:0071873 biolink:BiologicalProcess response to norepinephrine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. go-plus.json response to norepinephrine stimulus|response to noradrenaline stimulus http://purl.obolibrary.org/obo/GO_0071873 CHEBI:3792 biolink:ChemicalSubstance cobalt-precorrin-4 go-plus.json http://purl.obolibrary.org/obo/CHEBI_3792 UBERON:0002110 biolink:AnatomicalEntity gall bladder An organ that aids digestion and stores bile produced by the liver[WP]. go-plus.json gallbladder|gall bladder|vesica biliaris|vesica fellea http://purl.obolibrary.org/obo/UBERON_0002110 GO:0071872 biolink:BiologicalProcess cellular response to epinephrine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. go-plus.json cellular response to adrenaline stimulus http://purl.obolibrary.org/obo/GO_0071872 CHEBI:3791 biolink:ChemicalSubstance cobalt-precorrin-3 go-plus.json http://purl.obolibrary.org/obo/CHEBI_3791 GO:0071871 biolink:BiologicalProcess response to epinephrine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. go-plus.json response to adrenaline stimulus|response to epinephrine stimulus http://purl.obolibrary.org/obo/GO_0071871 GO:0140050 biolink:BiologicalProcess negative regulation of endocardial cushion to mesenchymal transition Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition. go-plus.json http://purl.obolibrary.org/obo/GO_0140050 UBERON:0002113 biolink:AnatomicalEntity kidney A paired organ of the urinary tract which has the production of urine as its primary function. go-plus.json reniculate kidney http://purl.obolibrary.org/obo/UBERON_0002113 CHEBI:3794 biolink:ChemicalSubstance cobalt-precorrin-6A go-plus.json http://purl.obolibrary.org/obo/CHEBI_3794 UBERON:0002112 biolink:AnatomicalEntity smooth muscle of esophagus A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]. go-plus.json non-striated muscle of gullet|non-striated muscle of esophagus|involuntary muscle of oesophagus|oesophagus smooth muscle|smooth muscle of gullet|oesophagus involuntary muscle|smooth muscle tissue of gullet|esophagus smooth muscle tissue|gullet smooth muscle tissue|gullet non-striated muscle|esophagus non-striated muscle|gullet smooth muscle|esophagus smooth muscle|non-striated muscle of oesophagus|involuntary muscle of esophagus|involuntary muscle of gullet|smooth muscle of oesophagus|esophagus involuntary muscle|smooth muscle tissue of oesophagus|gullet involuntary muscle|oesophagus non-striated muscle|esophageal smooth muscle|oesophagus smooth muscle tissue|smooth muscle tissue of esophagus http://purl.obolibrary.org/obo/UBERON_0002112 GO:0071870 biolink:BiologicalProcess cellular response to catecholamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. go-plus.json http://purl.obolibrary.org/obo/GO_0071870 GO:0022904 biolink:BiologicalProcess respiratory electron transport chain A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. Wikipedia:Electron_transfer go-plus.json oxidized glutathione reduction|protein-disulfide reduction|6-phosphofructokinase reduction|electron transfer|other pathways of electron transport|dihydrolipoamide reduction|dihydrobiopterin reduction|dihydropteridine reduction|dihydrolipoylprotein reduction http://purl.obolibrary.org/obo/GO_0022904 GO:1900778 biolink:BiologicalProcess fumiquinazoline A biosynthetic process The chemical reactions and pathways resulting in the formation of fumiquinazoline A. go-plus.json fumiquinazoline A biosynthesis|fumiquinazoline A anabolism|fumiquinazoline A synthesis|fumiquinazoline A formation http://purl.obolibrary.org/obo/GO_1900778 GO:1900777 biolink:BiologicalProcess fumiquinazoline A catabolic process The chemical reactions and pathways resulting in the breakdown of fumiquinazoline A. go-plus.json fumiquinazoline A degradation|fumiquinazoline A catabolism|fumiquinazoline A breakdown http://purl.obolibrary.org/obo/GO_1900777 GO:1900779 biolink:BiologicalProcess fumiquinazoline C metabolic process The chemical reactions and pathways involving fumiquinazoline C. go-plus.json fumiquinazoline C metabolism http://purl.obolibrary.org/obo/GO_1900779 GO:1900774 biolink:BiologicalProcess fumiquinazoline catabolic process The chemical reactions and pathways resulting in the breakdown of fumiquinazoline. go-plus.json fumiquinazoline degradation|fumiquinazolines breakdown|fumiquinazoline catabolism|fumiquinazoline breakdown|fumiquinazolines catabolic process|fumiquinazolines catabolism|fumiquinazolines degradation http://purl.obolibrary.org/obo/GO_1900774 CHEBI:35517 biolink:ChemicalSubstance 5beta-cholestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35517 chebi_ph7_3 GO:1900773 biolink:BiologicalProcess fumiquinazoline metabolic process The chemical reactions and pathways involving fumiquinazoline. go-plus.json fumiquinazolines metabolic process|fumiquinazoline metabolism|fumiquinazolines metabolism http://purl.obolibrary.org/obo/GO_1900773 CHEBI:35516 biolink:ChemicalSubstance cholestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35516 chebi_ph7_3 CHEBI:35519 biolink:ChemicalSubstance cholane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35519 chebi_ph7_3 GO:1900776 biolink:BiologicalProcess fumiquinazoline A metabolic process The chemical reactions and pathways involving fumiquinazoline A. go-plus.json fumiquinazoline A metabolism http://purl.obolibrary.org/obo/GO_1900776 CHEBI:35518 biolink:ChemicalSubstance campestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35518 chebi_ph7_3 GO:1900775 biolink:BiologicalProcess fumiquinazoline biosynthetic process The chemical reactions and pathways resulting in the formation of fumiquinazoline. go-plus.json fumiquinazoline biosynthesis|fumiquinazolines anabolism|fumiquinazoline anabolism|fumiquinazolines synthesis|fumiquinazolines biosynthesis|fumiquinazolines biosynthetic process|fumiquinazoline synthesis|fumiquinazolines formation|fumiquinazoline formation http://purl.obolibrary.org/obo/GO_1900775 GO:1900770 biolink:BiologicalProcess fumitremorgin B metabolic process The chemical reactions and pathways involving fumitremorgin B. go-plus.json Lanosulin metabolic process|fumitremorgin B metabolism|Lanosulin metabolism http://purl.obolibrary.org/obo/GO_1900770 GO:1900772 biolink:BiologicalProcess fumitremorgin B biosynthetic process The chemical reactions and pathways resulting in the formation of fumitremorgin B. go-plus.json fumitremorgin B anabolism|fumitremorgin B biosynthesis|Lanosulin biosynthesis|fumitremorgin B synthesis|Lanosulin biosynthetic process|Lanosulin anabolism|fumitremorgin B formation|Lanosulin synthesis|Lanosulin formation http://purl.obolibrary.org/obo/GO_1900772 GO:1900771 biolink:BiologicalProcess fumitremorgin B catabolic process The chemical reactions and pathways resulting in the breakdown of fumitremorgin B. go-plus.json fumitremorgin B breakdown|Lanosulin degradation|Lanosulin breakdown|fumitremorgin B catabolism|Lanosulin catabolic process|Lanosulin catabolism|fumitremorgin B degradation http://purl.obolibrary.org/obo/GO_1900771 GO:0140084 biolink:BiologicalProcess sexual macrocyst formation The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum. go-plus.json macrocyst formation|sexual fusion http://purl.obolibrary.org/obo/GO_0140084 CHEBI:35512 biolink:ChemicalSubstance ergostane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35512 chebi_ph7_3 CHEBI:3766 biolink:ChemicalSubstance clozapine go-plus.json http://purl.obolibrary.org/obo/CHEBI_3766 CHEBI:35515 biolink:ChemicalSubstance 5alpha-cholestane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35515 chebi_ph7_3 UBERON:0002104 biolink:AnatomicalEntity visual system The sensory system subserving the sense of vision. go-plus.json visual organ system|photosensory system http://purl.obolibrary.org/obo/UBERON_0002104 UBERON:0002103 biolink:AnatomicalEntity hindlimb A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts. go-plus.json inferior member|free part of lower limb|membrum inferius|hind limb|pelvic appendage|membrum inferius|lower extremity|lower limb|hindlimb|hind-limb|free lower limb http://purl.obolibrary.org/obo/UBERON_0002103 UBERON:0002106 biolink:AnatomicalEntity spleen the organ that functions to filter blood and to store red corpuscles and platelets go-plus.json lien http://purl.obolibrary.org/obo/UBERON_0002106 UBERON:0002105 biolink:AnatomicalEntity vestibulo-auditory system Sensory system responsible for the perception of spatial orientation and auditory stimuli. go-plus.json vestibuloauditory system|auditory system|vestibuloauditory system|auditory/vestibular system|auditory organ system http://purl.obolibrary.org/obo/UBERON_0002105 UBERON:0002100 biolink:AnatomicalEntity trunk Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. go-plus.json Rumpf|torso|thoracolumbar region|trunk region http://purl.obolibrary.org/obo/UBERON_0002100 GO:0140081 biolink:MolecularActivity glycosylated region protein binding Binding to a glycosylated region of a protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140081 GO:0140080 biolink:MolecularActivity class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH. go-plus.json endonuclease IV|endonuclease III http://purl.obolibrary.org/obo/GO_0140080 UBERON:0002102 biolink:AnatomicalEntity forelimb A (free) limb that is connected to a pectoral girdle. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pectoral girdle and its parts. go-plus.json pectoral limb|anteriormost limb|upper extremity|fore limb|upper limb|membrum superius|forelimb|foreleg|pectoral flipper|superior member|free upper limb|free part of upper limb http://purl.obolibrary.org/obo/UBERON_0002102 GO:0140083 biolink:MolecularActivity ATP-dependent protein-DNA unloading activity Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction. go-plus.json protein-DNA unloading ATPase activity http://purl.obolibrary.org/obo/GO_0140083 UBERON:0002101 biolink:AnatomicalEntity limb A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts. go-plus.json limb sensu Vertebrata|flipper|extremity|extremities|pentadactyl limb|free limb|tetrapod limb http://purl.obolibrary.org/obo/UBERON_0002101 GO:0140082 biolink:MolecularActivity SUMO-ubiquitin ligase activity Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. go-plus.json http://purl.obolibrary.org/obo/GO_0140082 GO:0071891 biolink:BiologicalProcess N-terminal peptidyl-proline dimethylation involved in translation An N-terminal peptidyl-proline dimethylation process that contributes to translation. go-plus.json http://purl.obolibrary.org/obo/GO_0071891 GO:0071890 biolink:MolecularActivity bicarbonate binding Binding to bicarbonate ions (CHO3-). go-plus.json CHO3- ion binding binding|hydrogencarbonate binding http://purl.obolibrary.org/obo/GO_0071890 GO:1900789 biolink:BiologicalProcess pseurotin A catabolic process The chemical reactions and pathways resulting in the breakdown of pseurotin A. go-plus.json pseurotin A breakdown|Pseurotin degradation|Pseurotin breakdown|pseurotin A catabolism|Pseurotin catabolic process|Pseurotin catabolism|pseurotin A degradation http://purl.obolibrary.org/obo/GO_1900789 GO:1900788 biolink:BiologicalProcess pseurotin A metabolic process The chemical reactions and pathways involving pseurotin A. go-plus.json Pseurotin metabolic process|pseurotin A metabolism|Pseurotin metabolism http://purl.obolibrary.org/obo/GO_1900788 GO:1900785 biolink:BiologicalProcess naphtho-gamma-pyrone metabolic process The chemical reactions and pathways involving naphtho-gamma-pyrone. go-plus.json naphtho-gamma-pyrone metabolism|naphtho-gamma-pyrones metabolic process|naphtho-gamma-pyrones metabolism http://purl.obolibrary.org/obo/GO_1900785 GO:1900784 biolink:BiologicalProcess fumiquinazoline F biosynthetic process The chemical reactions and pathways resulting in the formation of fumiquinazoline F. go-plus.json fumiquinazoline F anabolism|fumiquinazoline F biosynthesis|fumiquinazoline F synthesis|fumiquinazoline F formation http://purl.obolibrary.org/obo/GO_1900784 GO:1900787 biolink:BiologicalProcess naphtho-gamma-pyrone biosynthetic process The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone. go-plus.json naphtho-gamma-pyrone biosynthesis|naphtho-gamma-pyrones anabolism|naphtho-gamma-pyrones synthesis|naphtho-gamma-pyrones formation|naphtho-gamma-pyrone anabolism|naphtho-gamma-pyrones biosynthesis|naphtho-gamma-pyrone synthesis|naphtho-gamma-pyrones biosynthetic process|naphtho-gamma-pyrone formation http://purl.obolibrary.org/obo/GO_1900787 GO:1900786 biolink:BiologicalProcess naphtho-gamma-pyrone catabolic process The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone. go-plus.json naphtho-gamma-pyrones catabolic process|naphtho-gamma-pyrone degradation|naphtho-gamma-pyrone breakdown|naphtho-gamma-pyrones catabolism|naphtho-gamma-pyrones degradation|naphtho-gamma-pyrones breakdown|naphtho-gamma-pyrone catabolism http://purl.obolibrary.org/obo/GO_1900786 GO:1900781 biolink:BiologicalProcess fumiquinazoline C biosynthetic process The chemical reactions and pathways resulting in the formation of fumiquinazoline C. go-plus.json fumiquinazoline C biosynthesis|fumiquinazoline C anabolism|fumiquinazoline C synthesis|fumiquinazoline C formation http://purl.obolibrary.org/obo/GO_1900781 GO:1900780 biolink:BiologicalProcess fumiquinazoline C catabolic process The chemical reactions and pathways resulting in the breakdown of fumiquinazoline C. go-plus.json fumiquinazoline C degradation|fumiquinazoline C breakdown|fumiquinazoline C catabolism http://purl.obolibrary.org/obo/GO_1900780 GO:1900783 biolink:BiologicalProcess fumiquinazoline F catabolic process The chemical reactions and pathways resulting in the breakdown of fumiquinazoline F. go-plus.json fumiquinazoline F degradation|fumiquinazoline F breakdown|fumiquinazoline F catabolism http://purl.obolibrary.org/obo/GO_1900783 GO:1900782 biolink:BiologicalProcess fumiquinazoline F metabolic process The chemical reactions and pathways involving fumiquinazoline F. go-plus.json fumiquinazoline F metabolism http://purl.obolibrary.org/obo/GO_1900782 GO:0140074 biolink:BiologicalProcess cardiac endothelial to mesenchymal transition A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes. go-plus.json EndMT|EndoMT http://purl.obolibrary.org/obo/GO_0140074 GO:1900790 biolink:BiologicalProcess pseurotin A biosynthetic process The chemical reactions and pathways resulting in the formation of pseurotin A. go-plus.json Pseurotin formation|pseurotin A biosynthesis|pseurotin A anabolism|Pseurotin biosynthesis|pseurotin A synthesis|Pseurotin biosynthetic process|Pseurotin anabolism|pseurotin A formation|Pseurotin synthesis http://purl.obolibrary.org/obo/GO_1900790 GO:0140076 biolink:BiologicalProcess negative regulation of lipoprotein transport Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0140076 CHEBI:35522 biolink:ChemicalSubstance beta-adrenergic agonist go-plus.json http://purl.obolibrary.org/obo/CHEBI_35522 GO:0140075 biolink:BiologicalProcess regulation of lipoprotein transport Any process that controls lipoprotein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0140075 CHEBI:35524 biolink:ChemicalSubstance sympathomimetic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35524 GO:0140078 biolink:MolecularActivity class I DNA-(apurinic or apyrimidinic site) endonuclease activity Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate. MetaCyc:4.2.99.18-RXN|EC:4.2.99.18 go-plus.json DNA-(apurinic or apyrimidinic site) lyase activity|class I DNA-(apurinic or apyrimidinic site) lyase activity|AP endonuclease class I activity|AP site-DNA 5'-phosphomonoester-lyase activity|DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity http://purl.obolibrary.org/obo/GO_0140078 GO:0140077 biolink:BiologicalProcess positive regulation of lipoprotein transport Any process that activates or increases the rate or extent of lipoprotein transport. go-plus.json http://purl.obolibrary.org/obo/GO_0140077 CHEBI:35523 biolink:ChemicalSubstance bronchodilator agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35523 CHEBI:35526 biolink:ChemicalSubstance hypoglycemic agent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35526 GO:0140079 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140079 GO:0071899 biolink:BiologicalProcess obsolete negative regulation of estrogen receptor binding OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071899 GO:0071898 biolink:BiologicalProcess obsolete regulation of estrogen receptor binding OBSOLETE. Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor. go-plus.json http://purl.obolibrary.org/obo/GO_0071898 GO:0071897 biolink:BiologicalProcess DNA biosynthetic process The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. go-plus.json DNA biosynthesis|DNA anabolism|DNA synthesis|DNA formation http://purl.obolibrary.org/obo/GO_0071897 GO:0071896 biolink:BiologicalProcess protein localization to adherens junction Any process in which a protein is transported to, and/or maintained at the adherens junction. go-plus.json protein localization in cell-cell adherens junction|protein localisation to adherens junction|protein localisation in cell-cell adherens junction|protein localization to cell-cell adherens junction|protein localization in adherens junction|protein localisation to cell-cell adherens junction|protein localisation in adherens junction http://purl.obolibrary.org/obo/GO_0071896 GO:0071895 biolink:BiologicalProcess odontoblast differentiation The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. go-plus.json http://purl.obolibrary.org/obo/GO_0071895 GO:0071894 biolink:BiologicalProcess histone H2B conserved C-terminal lysine ubiquitination A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals. go-plus.json budding yeast H2B K123 ubiquitination|mammalian H2B K120 ubiquitination|fission yeast H2B K119 ubiquitination http://purl.obolibrary.org/obo/GO_0071894 GO:0071893 biolink:BiologicalProcess BMP signaling pathway involved in nephric duct formation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation. go-plus.json BMP signalling pathway involved in nephric duct formation http://purl.obolibrary.org/obo/GO_0071893 GO:0071892 biolink:BiologicalProcess thrombocyte activation A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals. go-plus.json blood coagulation, thrombocyte activation http://purl.obolibrary.org/obo/GO_0071892 GO:1900799 biolink:BiologicalProcess cordyol C biosynthetic process The chemical reactions and pathways resulting in the formation of cordyol C. go-plus.json cordyol C anabolism|cordyol C biosynthesis|cordyol C synthesis|cordyol C formation http://purl.obolibrary.org/obo/GO_1900799 GO:0140027 biolink:BiologicalProcess establishment of contractile vacuole localization The directed movement of the contractile vacuole to a specific location. go-plus.json http://purl.obolibrary.org/obo/GO_0140027 GO:1900796 biolink:BiologicalProcess terrequinone A biosynthetic process The chemical reactions and pathways resulting in the formation of terrequinone A. go-plus.json terrequinone A biosynthesis|terrequinone A anabolism|terrequinone A synthesis|terrequinone A formation http://purl.obolibrary.org/obo/GO_1900796 GO:0140026 biolink:BiologicalProcess contractile vacuole dissociation from plasma membrane The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network. go-plus.json contractile vacuole detethering from plasma membrane http://purl.obolibrary.org/obo/GO_0140026 GO:1900795 biolink:BiologicalProcess terrequinone A catabolic process The chemical reactions and pathways resulting in the breakdown of terrequinone A. go-plus.json terrequinone A degradation|terrequinone A breakdown|terrequinone A catabolism http://purl.obolibrary.org/obo/GO_1900795 GO:1900798 biolink:BiologicalProcess cordyol C catabolic process The chemical reactions and pathways resulting in the breakdown of cordyol C. go-plus.json cordyol C catabolism|cordyol C degradation|cordyol C breakdown http://purl.obolibrary.org/obo/GO_1900798 GO:0140029 biolink:BiologicalProcess exocytic process The cellular processes that contribute to exocytosis. go-plus.json http://purl.obolibrary.org/obo/GO_0140029 gocheck_do_not_annotate GO:0140028 biolink:BiologicalProcess pore formation during contractile vacuole discharge The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes. go-plus.json http://purl.obolibrary.org/obo/GO_0140028 GO:1900797 biolink:BiologicalProcess cordyol C metabolic process The chemical reactions and pathways involving cordyol C. go-plus.json cordyol C metabolism http://purl.obolibrary.org/obo/GO_1900797 GO:1900792 biolink:BiologicalProcess shamixanthone catabolic process The chemical reactions and pathways resulting in the breakdown of shamixanthone. go-plus.json shamixanthone breakdown|shamixanthone degradation|shamixanthone catabolism http://purl.obolibrary.org/obo/GO_1900792 GO:1900791 biolink:BiologicalProcess shamixanthone metabolic process The chemical reactions and pathways involving shamixanthone. go-plus.json shamixanthone metabolism http://purl.obolibrary.org/obo/GO_1900791 GO:1900794 biolink:BiologicalProcess terrequinone A metabolic process The chemical reactions and pathways involving terrequinone A. go-plus.json terrequinone A metabolism http://purl.obolibrary.org/obo/GO_1900794 GO:1900793 biolink:BiologicalProcess shamixanthone biosynthetic process The chemical reactions and pathways resulting in the formation of shamixanthone. go-plus.json shamixanthone biosynthesis|shamixanthone anabolism|shamixanthone synthesis|shamixanthone formation http://purl.obolibrary.org/obo/GO_1900793 GO:0140021 biolink:BiologicalProcess mitochondrial ADP transmembrane transport The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion. go-plus.json http://purl.obolibrary.org/obo/GO_0140021 UBERON:0002164 biolink:AnatomicalEntity tectobulbar tract A long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. go-plus.json tecto-bulbar tract|tractus tectobulbaris http://purl.obolibrary.org/obo/UBERON_0002164 GO:0140020 biolink:CellularComponent DNA methyltransferase complex A protein complex that possesses DNA methyltransferase activity. go-plus.json http://purl.obolibrary.org/obo/GO_0140020 GO:0140023 biolink:BiologicalProcess tRNA adenosine deamination to inosine The removal of an amine group from an adenosine to produce inosine within a tRNA molecule. go-plus.json A-to-I tRNA editing http://purl.obolibrary.org/obo/GO_0140023 GO:0140022 biolink:CellularComponent cnida A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria. go-plus.json cnidae (plural) http://purl.obolibrary.org/obo/GO_0140022 GO:0140025 biolink:BiologicalProcess contractile vacuole tethering involved in discharge The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. go-plus.json contractile vacuole tethering to plasma membrane http://purl.obolibrary.org/obo/GO_0140025 GO:0140024 biolink:BiologicalProcess plus-end-directed endosome transport along mitotic spindle midzone microtubule The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination. go-plus.json http://purl.obolibrary.org/obo/GO_0140024 UBERON:0002169 biolink:AnatomicalEntity alveolar sac The small terminal dilation of the alveolar ducts around which the alveoli form pocket-like clusters go-plus.json sacculus alveolaris|air sac|pulmonary alveolar sac http://purl.obolibrary.org/obo/UBERON_0002169 UBERON:0002166 biolink:AnatomicalEntity endocardium of atrium Endocardium that is part of the atrium. go-plus.json endocardium of atrium of heart|atrial endocardium|Cardiac atria endocardium|atrium endocardial tissue|endocardium of cardiac atrium|endocardium of Cardiac atria|cardiac atrium endocardium|endocardium of heart atrium|atrium endocardium|heart atrium endocardium|atrium of heart endocardium http://purl.obolibrary.org/obo/UBERON_0002166 UBERON:0002165 biolink:AnatomicalEntity endocardium The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. go-plus.json endocardial tissue|heart endocardial tissue|heart endocardium|endocardial lining http://purl.obolibrary.org/obo/UBERON_0002165 UBERON:0002168 biolink:AnatomicalEntity left lung Lung which consists of the left upper lobe and left lower lobe.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0002168 UBERON:0002167 biolink:AnatomicalEntity right lung Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA] go-plus.json http://purl.obolibrary.org/obo/UBERON_0002167 CHEBI:35506 biolink:ChemicalSubstance alkaloid fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35506 GO:0140016 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140016 CHEBI:35505 biolink:ChemicalSubstance hydrate go-plus.json http://purl.obolibrary.org/obo/CHEBI_35505 CHEBI:35508 biolink:ChemicalSubstance steroid fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35508 GO:0140018 biolink:BiologicalProcess regulation of cytoplasmic translational fidelity Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code. go-plus.json http://purl.obolibrary.org/obo/GO_0140018 CHEBI:11515 biolink:ChemicalSubstance 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate go-plus.json http://purl.obolibrary.org/obo/CHEBI_11515 CHEBI:35507 biolink:ChemicalSubstance natural product fundamental parent go-plus.json http://purl.obolibrary.org/obo/CHEBI_35507 CHEBI:35509 biolink:ChemicalSubstance androstane go-plus.json http://purl.obolibrary.org/obo/CHEBI_35509 chebi_ph7_3 UBERON:0002153 biolink:AnatomicalEntity fastigial nucleus the most medial of the cerebellar nuclei; it receives its afferent input from Purkinje cells of the flocculonodular lobe and the vermis, and most of its efferent connections travel via the inferior cerebellar peduncle to the vestibular nuclei and to the medullary reticular formation go-plus.json nucleus fastigii|fastigial cerebellar nucleus|fasciculosus thalamic nucleus|nucleus fastigii cerebelli|medial cerebellar nucleus|medial (fastigial) nucleus|nucleus (motorius) tecti cerebelli|medial nucleus of cerebellum|nucleus fastigiatus|nucleus fastigius cerebelli|roof nucleus-1|nucleus fastigii http://purl.obolibrary.org/obo/UBERON_0002153 GO:0140010 biolink:MolecularActivity D-aspartate transmembrane transporter activity Enables the transfer of D-aspartate from one side of a membrane to the other. go-plus.json http://purl.obolibrary.org/obo/GO_0140010 CHEBI:35500 biolink:ChemicalSubstance 1,4-benzodiazepinone go-plus.json http://purl.obolibrary.org/obo/CHEBI_35500 GO:0140014 biolink:BiologicalProcess mitotic nuclear division A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. go-plus.json mitosis http://purl.obolibrary.org/obo/GO_0140014 goslim_generic|goslim_chembl CHEBI:35504 biolink:ChemicalSubstance addition compound go-plus.json http://purl.obolibrary.org/obo/CHEBI_35504 GO:0140013 biolink:BiologicalProcess meiotic nuclear division One of the two nuclear divisions that occur as part of the meiotic cell cycle. go-plus.json meiosis http://purl.obolibrary.org/obo/GO_0140013 UBERON:0002154 biolink:AnatomicalEntity lateral reticular nucleus A nucleus of the lateral medullary nuclear complex. go-plus.json lateral reticular nucleus (medulla)|lateral reticular nuclei|nucleus reticularis lateralis medullae oblongatae http://purl.obolibrary.org/obo/UBERON_0002154 GO:0140049 biolink:BiologicalProcess regulation of endocardial cushion to mesenchymal transition Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition. go-plus.json http://purl.obolibrary.org/obo/GO_0140049 GO:0140048 biolink:BiologicalProcess manganese ion export across plasma membrane The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region. go-plus.json manganese ion export from cell http://purl.obolibrary.org/obo/GO_0140048 GO:0140041 biolink:BiologicalProcess cellular detoxification of methylglyoxal Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. go-plus.json http://purl.obolibrary.org/obo/GO_0140041 GO:0140040 biolink:BiologicalProcess mitochondrial polycistronic RNA processing The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs. go-plus.json http://purl.obolibrary.org/obo/GO_0140040 GO:0140043 biolink:BiologicalProcess lipid droplet localization to prospore membrane leading edge Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge. go-plus.json adiposome localization to forespore membrane leading edge|lipid particle localization to forespore membrane leading edge|adiposome localization to FSM membrane leading edge|lipid body localization to forespore membrane leading edge|lipid particle localization to FSM membrane leading edge|lipid body localization to FSM membrane leading edge|adiposome localization to ascospore-type prospore membrane leading edge|lipid particle localization to ascospore-type prospore membrane leading edge|lipid body localization to ascospore-type prospore membrane leading edge http://purl.obolibrary.org/obo/GO_0140043 UBERON:0002142 biolink:AnatomicalEntity pedunculopontine tegmental nucleus The pedunculopontine nucleus (PPN) (or pedunculopontine tegmental nucleus, PPTN) is located in the brainstem, caudal to the substantia nigra and adjacent to the superior cerebellar peduncle. It is composed by a wide variety of neurochemical cell types, including cholinergic, glutamatergic and GABAergic cells. In the classical sense, the PPN is considered to be one of the main components of the reticular activating system. [WP,unvetted]. go-plus.json nucleus pedunculopontinus|peduncular pontine nucleus|pedunculopontine nucleus|PPTg|nucleus tegmenti pedunculopontinus http://purl.obolibrary.org/obo/UBERON_0002142 GO:0140042 biolink:BiologicalProcess lipid droplet formation A process that results in the assembly, arrangement of constituent parts of a lipid droplet. go-plus.json lipid body formation|adiposome formation|lipid particle formation http://purl.obolibrary.org/obo/GO_0140042 GO:0140045 biolink:OntologyClass go-plus.json http://purl.obolibrary.org/obo/GO_0140045 UBERON:0002148 biolink:AnatomicalEntity locus ceruleus The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. go-plus.json loci coeruleus|nucleus caeruleus|substantia ferruginea|locus coeruleus|nucleus pigmentosus pontis|blue nucleus|locus cinereus|nucleus loci caerulei|locus coeruleus (Vicq d'Azyr)|nucleus of locus caeruleus|caerulean nucleus|locus coeruleu|locus caeruleus http://purl.obolibrary.org/obo/UBERON_0002148 UBERON:0002149 biolink:AnatomicalEntity superior salivatory nucleus Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). go-plus.json nucleus salivatorius superior|nucleus salivatorius rostralis|nucleus salivarius superior|nucleus salivatorius cranialis|superior salivary nucleus http://purl.obolibrary.org/obo/UBERON_0002149 UBERON:0002146 biolink:AnatomicalEntity pulmonary valve the semilunar valve of the heart that lies between the right ventricle and the pulmonary artery. go-plus.json pulmonic valve|valva trunci pulmonalis http://purl.obolibrary.org/obo/UBERON_0002146 UBERON:0002129 biolink:AnatomicalEntity cerebellar cortex The superficial gray matter of the cerebellum. It consists of three main layers, the molecular layer, the Purkinje cell layer and the granule cell layer. go-plus.json cortex of cerebellar hemisphere|cortex cerebellaris|cortex cerebelli http://purl.obolibrary.org/obo/UBERON_0002129 GO:0140037 biolink:MolecularActivity sumo-dependent protein binding Binding to a protein upon sumoylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140037 GO:0140039 biolink:BiologicalProcess cell-cell adhesion in response to extracellular stimulus The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus. go-plus.json http://purl.obolibrary.org/obo/GO_0140039 GO:0140030 biolink:MolecularActivity modification-dependent protein binding Binding to a protein upon post-translation modification of the target protein. go-plus.json modified protein binding http://purl.obolibrary.org/obo/GO_0140030 GO:0140032 biolink:MolecularActivity glycosylation-dependent protein binding Binding to a protein upon glycosylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140032 UBERON:0002130 biolink:AnatomicalEntity cerebellar nuclear complex The gray matter nuclei located in the center of the cerebellum, embedded in the white matter, which receive inhibitory (GABAergic) inputs from Purkinje cells in the cerebellar cortex and excitatory (glutamatergic) inputs from mossy fiber pathways; all output fibers of the cerebellum originate from the these nuclei[MP] go-plus.json intrinsic nuclei of cerebellum|roof nuclei-2|nuclei cerebelli|nuclei cerebelli|central nuclei|nuclei cerebellares|nuclei cerebellaris|deep cerebellar nuclei|deep cerebellar nuclear complex|intracerebellar nuclei|cerebellar nuclei http://purl.obolibrary.org/obo/UBERON_0002130 GO:0140031 biolink:MolecularActivity phosphorylation-dependent protein binding Binding to a protein upon phosphorylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140031 GO:0140034 biolink:MolecularActivity methylation-dependent protein binding Binding to a protein upon methylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140034 GO:0140033 biolink:MolecularActivity acetylation-dependent protein binding Binding to a protein upon acetylation of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140033 GO:0140036 biolink:MolecularActivity ubiquitin-dependent protein binding Binding to a protein upon ubiquitination of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140036 GO:0140035 biolink:MolecularActivity ubiquitination-like modification-dependent protein binding Binding to a protein upon modification by a ubiquitin-like protein of the target protein. go-plus.json http://purl.obolibrary.org/obo/GO_0140035 UBERON:0002137 biolink:AnatomicalEntity aortic valve Cardiac valve which has as its parts the anterior, right posterior and left posterior cusps, attached to the fibrous ring of aortic valve.[FMA] go-plus.json valva aortae http://purl.obolibrary.org/obo/UBERON_0002137 UBERON:0002133 biolink:AnatomicalEntity atrioventricular valve A cardial valve in the atrioventricular region that separates the atrium from the ventricle and prevent backflow from the ventricles into the atria during systole. go-plus.json AV valve|atrio-ventricular valve http://purl.obolibrary.org/obo/UBERON_0002133 UBERON:0002132 biolink:AnatomicalEntity dentate nucleus the largest and most lateral of the deep cerebellum nuclei; it receives axons of Purkinje cells in the lateral cerebellar hemisphere (neocerebellum) and receives its afferents from the premotor cortex and the supplementary motor cortex through the pontocerebellar system, and its efferents project through the superior cerebellar peduncle and is a major source of its fibers go-plus.json lateral cerebellar nucleus|lateral nucleus of cerebellum|nucleus lateralis cerebelli|nucleus dentatus|dentatothalamocortical fibers|dentate nucleus|dentate nucleus (Vicq d'Azyr)|dentate cerebellar nucleus|nucleus dentatus cerebelli http://purl.obolibrary.org/obo/UBERON_0002132 UBERON:0002135 biolink:AnatomicalEntity mitral valve An atrioventricular valve that is part of the outflow part of the left atrium. go-plus.json valva atrioventricularis sinistra|left atrioventricular valve|valva mitralis|bicuspid valve http://purl.obolibrary.org/obo/UBERON_0002135 UBERON:0002134 biolink:AnatomicalEntity tricuspid valve An atrioventricular valve that is part of the outflow part of the right atrium. go-plus.json valvula tricuspidalis|valva atrioventricularis dextra|right atrioventricular valve http://purl.obolibrary.org/obo/UBERON_0002134 PATO:0002236 biolink:NamedThing Graph CARO:0001001 biolink:NamedThing Graph CL:0000881 biolink:NamedThing Graph PATO:0002299 biolink:NamedThing Graph UBERON:0002027 biolink:NamedThing Graph PATO:0002462 biolink:NamedThing Graph CL:0000353 biolink:NamedThing Graph PATO:0000963 biolink:NamedThing Graph PATO:0002444 biolink:NamedThing Graph UBERON:0002025 biolink:NamedThing Graph PATO:0000608 biolink:NamedThing Graph PATO:0000964 biolink:NamedThing Graph PATO:0001171 biolink:NamedThing Graph PATO:0001987 biolink:NamedThing Graph MOD:00696 biolink:NamedThing Graph CL:0000508 biolink:NamedThing Graph UBERON:0002227 biolink:NamedThing Graph ENVO:00002030 biolink:NamedThing Graph PATO:0001185 biolink:NamedThing Graph PATO:0001190 biolink:NamedThing Graph PATO:0000407 biolink:NamedThing Graph UBERON:0008925 biolink:NamedThing Graph UBERON:0008926 biolink:NamedThing Graph PATO:0002519 biolink:NamedThing Graph CL:0007002 biolink:NamedThing Graph PATO:0000998 biolink:NamedThing Graph UBERON:0001384 biolink:NamedThing Graph UBERON:0010005 biolink:NamedThing Graph CL:0007001 biolink:NamedThing Graph PATO:0001548 biolink:NamedThing Graph PR:000015557 biolink:NamedThing Graph CL:0000335 biolink:NamedThing Graph CL:0000118 biolink:NamedThing Graph CL:0000555 biolink:NamedThing Graph PATO:0001735 biolink:NamedThing Graph UBERON:0002313 biolink:NamedThing Graph CL:0002082 biolink:NamedThing Graph CL:0002083 biolink:NamedThing Graph PATO:0001544 biolink:NamedThing Graph CL:1000309 biolink:NamedThing Graph PATO:0001297 biolink:NamedThing Graph UBERON:0005751 biolink:NamedThing Graph CHEBI:3311 biolink:NamedThing Graph CL:0000354 biolink:NamedThing Graph CL:0002173 biolink:NamedThing Graph CL:0002220 biolink:NamedThing Graph CL:1000303 biolink:NamedThing Graph PR:000007499 biolink:NamedThing Graph PR:000014841 biolink:NamedThing Graph PATO:0001547 biolink:NamedThing Graph CL:0000313 biolink:NamedThing Graph PATO:0010001 biolink:NamedThing Graph CL:0000352 biolink:NamedThing Graph PATO:0002422 biolink:NamedThing Graph PATO:0000610 biolink:NamedThing Graph CL:1000306 biolink:NamedThing Graph CL:0002073 biolink:NamedThing Graph CL:0002074 biolink:NamedThing Graph IDO:0000404 biolink:NamedThing Graph PATO:0002255 biolink:NamedThing Graph PATO:0002507 biolink:NamedThing Graph PR:000028527 biolink:NamedThing Graph PATO:0002468 biolink:NamedThing Graph BFO:0000024 biolink:NamedThing Graph ENVO:01000048 biolink:NamedThing Graph NBO:0000347 biolink:NamedThing Graph ENVO:00000446 biolink:NamedThing Graph CL:0002169 biolink:NamedThing Graph ENVO:00000447 biolink:NamedThing Graph CHEBI:22868 biolink:NamedThing Graph owl:Thing biolink:NamedThing Graph CL:0002199 biolink:NamedThing Graph UBERON:0005376 biolink:NamedThing Graph CL:0000652 biolink:NamedThing Graph CL:0002166 biolink:NamedThing Graph CL:0002258 biolink:NamedThing Graph OBI:0100026 biolink:NamedThing Graph PATO:0002045 biolink:NamedThing Graph CL:0005009 biolink:NamedThing Graph CL:0002312 biolink:NamedThing Graph CL:0002095 biolink:NamedThing Graph PR:000007636 biolink:NamedThing Graph PATO:0001748 biolink:NamedThing Graph CL:0002294 biolink:NamedThing Graph CL:0000432 biolink:NamedThing Graph CL:0000347 biolink:NamedThing Graph CL:0000446 biolink:NamedThing Graph CL:0000853 biolink:NamedThing Graph PATO:0002198 biolink:NamedThing Graph UBERON:0002512 biolink:NamedThing Graph CL:0000745 biolink:NamedThing Graph ENVO:00000568 biolink:NamedThing Graph NBO:0000412 biolink:NamedThing Graph CL:0002064 biolink:NamedThing Graph NBO:0000073 biolink:NamedThing Graph PATO:0001993 biolink:NamedThing Graph CHEBI:36277 biolink:NamedThing Graph CL:0000642 biolink:NamedThing Graph CL:0000214 biolink:NamedThing Graph PATO:0001187 biolink:NamedThing Graph PATO:0001690 biolink:NamedThing Graph